A0A096MKY8_PAPAN Loading...

Monocarboxylate transporter 2

Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate. Dimerization is functionally required and both subunits work cooperatively in transporting substrate.

AlphaFold DB , UniProt , Accession A0A096MKY8, Species PAPAN (Papio anubis, Olive baboon), Gene SLC16A7, Length 478 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.9	Very low	45	Very low	188 Å²	188	115.5 Å²	115.5	93%	0.926	68%	0.679	S	S	*	*				0	135.2	0	-72	177.6	177.9	0	0	108.7
2	P	36.3	Very low	46.3	Very low	80 Å²	80	113.8 Å²	113.8	52%	0.519	67%	0.674	S	S	.	*	P	Polyproline II helix	trans	-60.3	148.5	163.2	27.4	-31.2	0	0	0	108.9	M4 M363	P2-M4 PolarHBondContact O-N 3.43Å; P2-M363 HydrophobicContact CG-CE 4.43Å
3	P	34.1	Very low	48.1	Very low	123 Å²	123	107.2 Å²	107.2	80%	0.799	64%	0.636	S	S	*	*	P	Polyproline II helix	trans	-57.5	133.6	175.3	23	-30.4	0	0	0	109.1
4	M	43.8	Very low	49.8	Very low	129 Å²	129	104.9 Å²	104.9	64%	0.635	63%	0.625	S	S	*	*	P	Polyproline II helix	trans	-56.8	134.7	174.5	-75.7	-168.7	-76.5	0	0	108.5	P2 S6	P2-M4 PolarHBondContact O-N 3.43Å; M4-S6 PolarHBondContact O-N 2.59Å
5	P	43.2	Very low	51.3	Low	79 Å²	79	99.9 Å²	99.9	51%	0.513	59%	0.594	S	S	.	*	P	Polyproline II helix	trans	-46.8	127.7	162.1	-23.9	32.4	0	0	0	108.8	T7 Y140	P5-T7 PolarHBondContact O-N 2.98Å; P5-Y140 WeakPolarHBondContact CD-OH 3.06Å; P5-Y140 VanDerWaalsContact CG-OH 3.28Å; P5-Y140 WeakPolarHBondContact CG-OH 3.33Å
6	S	46.8	Very low	53.1	Low	123 Å²	123	94.7 Å²	94.7	86%	0.86	57%	0.567	S	S	*	*	S	Bend	trans	-64	-6.4	-176	45.4	0	0	0	0	113.7	M4	M4-S6 PolarHBondContact O-N 2.59Å
7	T	45.6	Very low	55.1	Low	105 Å²	105	92.7 Å²	92.7	64%	0.644	57%	0.571	S	S	*	*	S	Bend	trans	-122.8	117.8	177.3	43.4	0	0	0	0	110.8	P5	P5-T7 PolarHBondContact O-N 2.98Å
8	P	44.6	Very low	56.9	Low	97 Å²	97	92.7 Å²	92.7	63%	0.63	56%	0.559	S	S	*	*			trans	-63.9	148.5	170.8	25.2	-30.3	0	0	0	110.2
9	P	55.1	Low	58.5	Low	50 Å²	50	87.8 Å²	87.8	33%	0.325	53%	0.529	S	S	.	.			trans	-59.2	149	175.8	23.9	-31.6	0	0	0	110.7	H11	P9-H11 CarbonylContact O-C 3.56Å; P9-H11 PolarHBondContact O-N 2.78Å
10	P	46.8	Very low	60.2	Low	129 Å²	129	88.8 Å²	88.8	84%	0.838	52%	0.523	S	S	*	.	S	Bend	trans	-57.9	-17.9	-173.8	18.1	-30.1	0	0	0	114.7
11	H	59	Low	61.8	Low	168 Å²	168	87.3 Å²	87.3	78%	0.778	52%	0.515	S	S	*	.	S	Bend	trans	-124	103.7	160	-67.5	-63.3	0	0	0	108.7	P9	P9-H11 CarbonylContact O-C 3.56Å; P9-H11 PolarHBondContact O-N 2.78Å
12	P	60.3	Low	64.2	Low	95 Å²	95	78.3 Å²	78.3	62%	0.617	47%	0.471	S	S	*	.			trans	-65.5	134.9	177	25.9	-31.4	0	0	0	108.9
13	P	70.3	Confident	66.9	Low	28 Å²	28	74.6 Å²	74.6	18%	0.182	45%	0.447	C	S	.	.			trans	-63.8	151.8	175.1	25.2	-29.2	0	0	0	110	D15 K137 Y140	P13-D15 PolarHBondContact O-N 3.28Å; P13-K137 VanDerWaalsContact CB-O 3.31Å; P13-K137 WeakPolarHBondContact CB-O 3.41Å; P13-Y140 HydrophobicContact CG-CG 4.42Å
14	P	70.9	Confident	69.7	Low	75 Å²	75	70.5 Å²	70.5	49%	0.487	43%	0.427	S	S	.	.			trans	-63.4	-19.2	-168.5	22	-32.2	0	0	0	114.2	G16 Y138 L198	P14-G16 PolarHBondContact O-N 3.33Å; P14-Y138 HydrophobicContact CG-CD1 4.07Å; P14-L198 HydrophobicContact CG-CD1 4.11Å; P14-L198 HydrophobicContact CG-CD2 4.24Å
15	D	73.4	Confident	72	Confident	30 Å²	30	64.4 Å²	64.4	16%	0.16	40%	0.397	C	S	.	.	S	Bend	trans	49.4	29.7	175.4	-91	-32.2	0	0	0	113.5	P13 Y138 F139 Y140 R141	P13-D15 PolarHBondContact O-N 3.28Å; D15-Y138 PolarHBondContact N-O 3.3Å; D15-F139 WeakPolarHBondContact OD1-CA 3.32Å; D15-Y140 PolarHBondContact OD1-N 3.36Å; D15-R141 PolarHBondContact OD1-N 3.15Å; D15-R141 WeakPolarHBondContact OD2-CB 3.29Å; D15-R141 PolarHBondContact OD2-N 3.01Å; D15-R141 VanDerWaalsContact OD2-N 3.08Å
16	G	79	Confident	74.4	Confident	16 Å²	16	60.7 Å²	60.7	17%	0.165	37%	0.372	C	S	.	.	S	Bend	trans	170.7	-168.2	-173.8	0	0	0	0	0	113.8	P14 W18 G19	P14-G16 PolarHBondContact O-N 3.33Å; G16-W18 PolarHBondContact O-N 3.13Å; G16-G19 PolarHBondContact O-N 2.62Å
17	G	87.3	Confident	76.6	Confident	61 Å²	61	57 Å²	57	63%	0.629	34%	0.341	S	S	*	.	T	Hydrogen-bonded Turn	trans	61	-125.9	178.2	0	0	0	0	0	113.2	G19 W20	G17-G19 PolarHBondContact O-N 3.22Å; G17-W20 PolarHBondContact O-N 2.88Å; G17-W20 VanDerWaalsContact O-N 3.08Å
18	W	88.6	Confident	78.9	Confident	93 Å²	93	54.7 Å²	54.7	35%	0.352	32%	0.324	S	S	.	.	H	α-helix	trans	-58.3	-19.4	178.5	-161.8	-93.6	0	0	0	113.4	G16 W20 V21 V22 Y138 L194	G16-W18 PolarHBondContact O-N 3.13Å; W18-W20 PolarHBondContact O-N 3.07Å; W18-V21 HydrophobicContact CD2-CB 4.3Å; W18-V21 HydrophobicContact CD2-CG2 4.39Å; W18-V21 HydrophobicContact CE3-CG2 4.28Å; W18-V21 HydrophobicContact CH2-CG1 4.44Å; W18-V21 HydrophobicContact CZ2-CG1 4.09Å; W18-V21 WeakPolarHBondContact O-CB 3Å; W18-V21 PolarHBondContact O-N 3.16Å; W18-V21 VanDerWaalsContact O-N 3.13Å; W18-V22 WeakPolarHBondContact O-CG2 3.39Å; W18-V22 PolarHBondContact O-N 3.33Å; W18-Y138 HydrophobicContact CB-CE1 4.31Å; W18-L194 HydrophobicContact CZ2-CD2 4.24Å; W18-L194 PolarHBondContact NE1-O 3.15Å
19	G	87.1	Confident	81.2	Confident	0 Å²	0	50 Å²	50	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-55.4	-36.8	172.9	0	0	0	0	0	113.1	G16 G17 V22 V23 F139	G16-G19 PolarHBondContact O-N 2.62Å; G17-G19 PolarHBondContact O-N 3.22Å; G19-V22 WeakPolarHBondContact O-CB 3.48Å; G19-V22 PolarHBondContact O-N 3.06Å; G19-V23 WeakPolarHBondContact O-CG2 3.48Å; G19-V23 PolarHBondContact O-N 2.98Å; G19-F139 VanDerWaalsContact C-CZ 3.44Å; G19-F139 WeakPolarHBondContact O-CE2 3.32Å
20	W	91.9	Very high	83	Confident	106 Å²	106	47.7 Å²	47.7	40%	0.402	28%	0.279	S	S	.	.	H	α-helix	trans	-71.3	-33.2	178.3	-67	113.4	0	0	0	112.9	G17 W18 V22 V23 G24 F139 K142 L149	G17-W20 PolarHBondContact O-N 2.88Å; G17-W20 VanDerWaalsContact O-N 3.08Å; W18-W20 PolarHBondContact O-N 3.07Å; W20-V22 VanDerWaalsContact C-N 3.32Å; W20-V23 HydrophobicContact CE3-CG2 4.48Å; W20-V23 PolarHBondContact O-N 3.13Å; W20-G24 PolarHBondContact O-N 3.5Å; W20-F139 HydrophobicContact CD2-CZ 4.11Å; W20-F139 HydrophobicContact CE3-CZ 4.4Å; W20-F139 HydrophobicContact CG-CZ 4.43Å; W20-F139 HydrophobicContact CZ2-CE1 4.33Å; W20-K142 HydrophobicContact CZ2-CD 4.26Å; W20-L149 HydrophobicContact CZ3-CD2 4.4Å
21	V	93.1	Very high	85.2	Confident	58 Å²	58	41.5 Å²	41.5	35%	0.352	24%	0.239	S	C	.	.	H	α-helix	trans	-63.7	-41.9	171	-177.6	0	0	0	0	110.1	W18 V23 G24 A25 L194	W18-V21 HydrophobicContact CD2-CB 4.3Å; W18-V21 HydrophobicContact CD2-CG2 4.39Å; W18-V21 HydrophobicContact CE3-CG2 4.28Å; W18-V21 HydrophobicContact CH2-CG1 4.44Å; W18-V21 HydrophobicContact CZ2-CG1 4.09Å; W18-V21 WeakPolarHBondContact O-CB 3Å; W18-V21 PolarHBondContact O-N 3.16Å; W18-V21 VanDerWaalsContact O-N 3.13Å; V21-V23 VanDerWaalsContact C-N 3.3Å; V21-V23 PolarHBondContact O-N 3.26Å; V21-G24 PolarHBondContact O-N 2.9Å; V21-A25 PolarHBondContact O-N 3.42Å; V21-L194 HydrophobicContact CG1-CB 4.32Å; V21-L194 HydrophobicContact CG1-CD1 4.27Å; V21-L194 HydrophobicContact CG1-CD2 4.23Å
22	V	91.5	Very high	86.8	Confident	0 Å²	0	34.1 Å²	34.1	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-64	-35.2	175	173.8	0	0	0	0	111.7	W18 G19 W20 A25 A26 I134 Y138	W18-V22 WeakPolarHBondContact O-CG2 3.39Å; W18-V22 PolarHBondContact O-N 3.33Å; G19-V22 WeakPolarHBondContact O-CB 3.48Å; G19-V22 PolarHBondContact O-N 3.06Å; W20-V22 VanDerWaalsContact C-N 3.32Å; V22-A25 PolarHBondContact O-N 3.27Å; V22-A26 VanDerWaalsContact O-CB 3.3Å; V22-A26 WeakPolarHBondContact O-CB 3.3Å; V22-A26 PolarHBondContact O-N 2.96Å; V22-I134 HydrophobicContact CG1-CB 4.33Å; V22-I134 HydrophobicContact CG1-CD1 4.1Å; V22-I134 HydrophobicContact CG1-CG1 4.01Å; V22-I134 HydrophobicContact CG1-CG2 3.5Å; V22-Y138 HydrophobicContact CG1-CD2 4.35Å; V22-Y138 HydrophobicContact CG2-CD2 4.37Å; V22-Y138 HydrophobicContact CG2-CE1 4.18Å; V22-Y138 HydrophobicContact CG2-CE2 3.98Å
23	V	92.3	Very high	88.3	Confident	2 Å²	2	29.6 Å²	29.6	1%	0.012	18%	0.175	C	C	.	.	H	α-helix	trans	-65.8	-41.9	173.4	173.4	0	0	0	0	111.2	G19 W20 V21 A26 F27 I135 F139 A146 L149 A150	G19-V23 WeakPolarHBondContact O-CG2 3.48Å; G19-V23 PolarHBondContact O-N 2.98Å; W20-V23 HydrophobicContact CE3-CG2 4.48Å; W20-V23 PolarHBondContact O-N 3.13Å; V21-V23 VanDerWaalsContact C-N 3.3Å; V21-V23 PolarHBondContact O-N 3.26Å; V23-A26 PolarHBondContact O-N 3.31Å; V23-F27 WeakPolarHBondContact O-CB 3.14Å; V23-F27 PolarHBondContact O-N 2.88Å; V23-I135 HydrophobicContact CG2-CG1 4.48Å; V23-F139 HydrophobicContact CG2-CD2 4.31Å; V23-F139 HydrophobicContact CG2-CE2 3.54Å; V23-F139 HydrophobicContact CG2-CZ 4.17Å; V23-A146 HydrophobicContact CG2-CB 3.76Å; V23-L149 HydrophobicContact CG1-CB 4.05Å; V23-L149 HydrophobicContact CG1-CD2 3.78Å; V23-L149 HydrophobicContact CG1-CG 4.02Å; V23-A150 HydrophobicContact CG1-CB 4.5Å
24	G	93.1	Very high	89.3	Confident	37 Å²	37	30.2 Å²	30.2	38%	0.381	17%	0.174	S	C	.	.	H	α-helix	trans	-61.8	-41	173.2	0	0	0	0	0	112.8	W20 V21 F27 I28	W20-G24 PolarHBondContact O-N 3.5Å; V21-G24 PolarHBondContact O-N 2.9Å; G24-F27 WeakPolarHBondContact O-CB 3.4Å; G24-F27 PolarHBondContact O-N 3.16Å; G24-I28 PolarHBondContact O-N 3.4Å
25	A	93.1	Very high	90.4	Very high	1 Å²	1	26.6 Å²	26.6	1%	0.008	15%	0.151	C	C	.	.	H	α-helix	trans	-63.5	-44.5	173	0	0	0	0	0	112.2	V21 V22 F27 I28 S29 A191 L194 M195	V21-A25 PolarHBondContact O-N 3.42Å; V22-A25 PolarHBondContact O-N 3.27Å; A25-F27 VanDerWaalsContact C-N 3.31Å; A25-F27 PolarHBondContact O-N 3.45Å; A25-I28 PolarHBondContact O-N 3.39Å; A25-S29 PolarHBondContact O-N 2.89Å; A25-S29 PolarHBondContact O-OG 3.27Å; A25-A191 HydrophobicContact CB-CB 4.12Å; A25-A191 VanDerWaalsContact CB-O 3.31Å; A25-A191 WeakPolarHBondContact CB-O 3.36Å; A25-L194 HydrophobicContact CB-CB 4.01Å; A25-L194 HydrophobicContact CB-CD1 4.25Å; A25-M195 HydrophobicContact CB-CE 4.16Å; A25-M195 HydrophobicContact CB-CG 4.34Å
26	A	91.9	Very high	91.4	Very high	0 Å²	0	25.2 Å²	25.2	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-65.7	-33.8	177.2	0	0	0	0	0	112.3	V22 V23 I28 S29 I30 A131 I135 A150 M195	V22-A26 VanDerWaalsContact O-CB 3.3Å; V22-A26 WeakPolarHBondContact O-CB 3.3Å; V22-A26 PolarHBondContact O-N 2.96Å; V23-A26 PolarHBondContact O-N 3.31Å; A26-I28 VanDerWaalsContact C-N 3.3Å; A26-I28 PolarHBondContact O-N 2.88Å; A26-S29 PolarHBondContact O-N 3.23Å; A26-I30 WeakPolarHBondContact O-CB 3.49Å; A26-I30 WeakPolarHBondContact O-CG1 3.46Å; A26-I30 PolarHBondContact O-N 3.03Å; A26-A131 HydrophobicContact CB-CB 3.96Å; A26-I135 HydrophobicContact CB-CD1 3.52Å; A26-I135 HydrophobicContact CB-CG1 4Å; A26-A150 HydrophobicContact CB-CB 4.05Å; A26-M195 HydrophobicContact CB-CE 4.09Å
27	F	94	Very high	92	Very high	45 Å²	45	24.5 Å²	24.5	20%	0.197	14%	0.136	C	C	.	.	H	α-helix	trans	-56.8	-45.3	172.4	-178.6	-82.5	0	0	0	111.2	V23 G24 A25 G31 L149 G153 V156 F157	V23-F27 WeakPolarHBondContact O-CB 3.14Å; V23-F27 PolarHBondContact O-N 2.88Å; G24-F27 WeakPolarHBondContact O-CB 3.4Å; G24-F27 PolarHBondContact O-N 3.16Å; A25-F27 VanDerWaalsContact C-N 3.31Å; A25-F27 PolarHBondContact O-N 3.45Å; F27-G31 WeakPolarHBondContact O-CA 3.16Å; F27-G31 PolarHBondContact O-N 3.31Å; F27-L149 WeakPolarHBondContact CD2-O 3.35Å; F27-G153 VanDerWaalsContact CE2-N 3.26Å; F27-V156 HydrophobicContact CE1-CG1 4.47Å; F27-V156 HydrophobicContact CZ-CB 4.02Å; F27-V156 HydrophobicContact CZ-CG1 4.24Å; F27-V156 HydrophobicContact CZ-CG2 3.98Å; F27-F157 AromaticContact CD1-CE2 3.97Å; F27-F157 HydrophobicContact CD1-CE2 3.97Å; F27-F157 HydrophobicContact CE1-CD2 4.18Å; F27-F157 AromaticContact CE1-CE2 3.78Å; F27-F157 HydrophobicContact CE1-CE2 3.78Å
28	I	93.9	Very high	92.3	Very high	57 Å²	57	22 Å²	22	29%	0.292	11%	0.108	S	C	.	.	H	α-helix	trans	-67	-49.8	177.3	-63.1	169	0	0	0	110.7	G24 A25 A26 G31 F32 F157 A191	G24-I28 PolarHBondContact O-N 3.4Å; A25-I28 PolarHBondContact O-N 3.39Å; A26-I28 VanDerWaalsContact C-N 3.3Å; A26-I28 PolarHBondContact O-N 2.88Å; I28-G31 PolarHBondContact O-N 2.86Å; I28-F32 HydrophobicContact CG2-CD2 3.72Å; I28-F32 HydrophobicContact CG2-CE2 3.72Å; I28-F32 WeakPolarHBondContact O-CD2 3.35Å; I28-F32 PolarHBondContact O-N 3.22Å; I28-F157 HydrophobicContact CB-CZ 4.36Å; I28-F157 HydrophobicContact CG1-CZ 4.24Å; I28-F157 HydrophobicContact CG2-CZ 4.16Å; I28-A191 HydrophobicContact CB-CB 4.24Å; I28-A191 HydrophobicContact CG2-CB 4.25Å
29	S	93.3	Very high	92.5	Very high	0 Å²	0	17.6 Å²	17.6	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-61.7	-47	-178.9	-62.4	0	0	0	0	112.5	A25 A26 S33	A25-S29 PolarHBondContact O-N 2.89Å; A25-S29 PolarHBondContact O-OG 3.27Å; A26-S29 PolarHBondContact O-N 3.23Å; S29-S33 WeakPolarHBondContact O-CB 3.48Å; S29-S33 PolarHBondContact O-N 3.25Å; S29-S33 PolarHBondContact O-OG 3.09Å; S29-S33 VanDerWaalsContact O-OG 3.08Å
30	I	91.6	Very high	92.7	Very high	0 Å²	0	17.7 Å²	17.7	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-68.5	-38.6	178	-64.2	177.2	0	0	0	110.5	A26 S33 Y34 L128 A131 L132 A150 M151	A26-I30 WeakPolarHBondContact O-CB 3.49Å; A26-I30 WeakPolarHBondContact O-CG1 3.46Å; A26-I30 PolarHBondContact O-N 3.03Å; I30-S33 PolarHBondContact O-N 2.87Å; I30-Y34 HydrophobicContact CG2-CD2 3.74Å; I30-Y34 HydrophobicContact CG2-CE2 4.07Å; I30-Y34 PolarHBondContact O-N 3.38Å; I30-Y34 VanDerWaalsContact O-N 3.08Å; I30-L128 HydrophobicContact CB-CD1 4.46Å; I30-L128 HydrophobicContact CG1-CD1 3.95Å; I30-L128 HydrophobicContact CG2-CD1 4.3Å; I30-A131 HydrophobicContact CD1-CB 4.41Å; I30-A131 HydrophobicContact CG1-CB 4.06Å; I30-L132 HydrophobicContact CD1-CD2 3.82Å; I30-L132 HydrophobicContact CD1-CG 4.3Å; I30-A150 HydrophobicContact CD1-CB 3.83Å; I30-M151 HydrophobicContact CG2-CE 4.07Å
31	G	92.9	Very high	92.6	Very high	0 Å²	0	12.6 Å²	12.6	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-52.9	-59.9	174.4	0	0	0	0	0	111.5	F27 I28 S33 A35	F27-G31 WeakPolarHBondContact O-CA 3.16Å; F27-G31 PolarHBondContact O-N 3.31Å; I28-G31 PolarHBondContact O-N 2.86Å; G31-S33 PolarHBondContact O-N 3.31Å; G31-A35 WeakPolarHBondContact O-CB 3.46Å; G31-A35 PolarHBondContact O-N 3Å
32	F	92.8	Very high	92.5	Very high	12 Å²	12	10 Å²	10	5%	0.053	6%	0.056	C	C	.	.	H	α-helix	trans	-59.6	-47.5	176.7	-81.1	-64	0	0	0	112.6	I28 Y34 F36 F157 L184 L185	I28-F32 HydrophobicContact CG2-CD2 3.72Å; I28-F32 HydrophobicContact CG2-CE2 3.72Å; I28-F32 WeakPolarHBondContact O-CD2 3.35Å; I28-F32 PolarHBondContact O-N 3.22Å; F32-Y34 PolarHBondContact O-N 3.43Å; F32-F36 WeakPolarHBondContact O-CB 3.22Å; F32-F36 PolarHBondContact O-N 2.82Å; F32-F157 AromaticContact CD1-CD1 4Å; F32-F157 HydrophobicContact CD1-CD1 4Å; F32-F157 HydrophobicContact CD1-CE1 4.14Å; F32-F157 HydrophobicContact CD2-CD1 4.22Å; F32-F157 AromaticContact CD2-CE1 3.69Å; F32-F157 HydrophobicContact CD2-CE1 3.69Å; F32-F157 HydrophobicContact CD2-CZ 4.42Å; F32-F157 AromaticContact CE1-CD1 3.99Å; F32-F157 HydrophobicContact CE1-CD1 3.99Å; F32-F157 AromaticContact CE1-CE1 3.89Å; F32-F157 HydrophobicContact CE1-CE1 3.89Å; F32-F157 HydrophobicContact CE2-CD1 4.24Å; F32-F157 AromaticContact CE2-CE1 3.42Å; F32-F157 HydrophobicContact CE2-CE1 3.42Å; F32-F157 VanDerWaalsContact CE2-CE1 3.42Å; F32-F157 HydrophobicContact CE2-CZ 4.19Å; F32-F157 HydrophobicContact CG-CD1 4.12Å; F32-F157 HydrophobicContact CG-CE1 4.05Å; F32-F157 HydrophobicContact CZ-CD1 4.13Å; F32-F157 AromaticContact CZ-CE1 3.53Å; F32-F157 HydrophobicContact CZ-CE1 3.53Å; F32-L184 HydrophobicContact CE1-CB 4.17Å; F32-L184 HydrophobicContact CZ-CB 4.11Å; F32-L184 WeakPolarHBondContact CZ-O 3.33Å; F32-L185 HydrophobicContact CB-CD2 3.97Å; F32-L185 HydrophobicContact CD1-CD2 3.72Å; F32-L185 HydrophobicContact CE1-CD2 4.41Å; F32-L185 HydrophobicContact CG-CD2 3.98Å
33	S	93	Very high	92.5	Very high	0 Å²	0	10 Å²	10	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-58.1	-42.9	-176.9	-67.9	0	0	0	0	113.9	S29 I30 G31 P37 L124	S29-S33 WeakPolarHBondContact O-CB 3.48Å; S29-S33 PolarHBondContact O-N 3.25Å; S29-S33 PolarHBondContact O-OG 3.09Å; S29-S33 VanDerWaalsContact O-OG 3.08Å; I30-S33 PolarHBondContact O-N 2.87Å; G31-S33 PolarHBondContact O-N 3.31Å; S33-P37 VanDerWaalsContact O-CD 3.28Å; S33-P37 WeakPolarHBondContact O-CD 3.49Å; S33-L124 PolarHBondContact OG-O 3.15Å
34	Y	91.3	Very high	92.3	Very high	41 Å²	41	10.1 Å²	10.1	16%	0.161	6%	0.056	C	C	.	.	H	α-helix	trans	-89.5	-31.6	-179.2	-79.1	-68.6	0	0	0	114.5	I30 F32 M69 Y70 L128 M151 S154	I30-Y34 HydrophobicContact CG2-CD2 3.74Å; I30-Y34 HydrophobicContact CG2-CE2 4.07Å; I30-Y34 PolarHBondContact O-N 3.38Å; I30-Y34 VanDerWaalsContact O-N 3.08Å; F32-Y34 PolarHBondContact O-N 3.43Å; Y34-M69 HydrophobicContact CD1-CE 3.97Å; Y34-M69 HydrophobicContact CE1-CE 3.97Å; Y34-Y70 HydrophobicContact CE1-CE1 4.38Å; Y34-L128 HydrophobicContact CD2-CD1 4.18Å; Y34-L128 HydrophobicContact CE2-CD1 3.56Å; Y34-L128 HydrophobicContact CE2-CD2 3.93Å; Y34-L128 HydrophobicContact CE2-CG 4.42Å; Y34-M151 HydrophobicContact CD2-CE 4.22Å; Y34-M151 HydrophobicContact CE2-CE 3.58Å; Y34-S154 VanDerWaalsContact CB-OG 3.22Å; Y34-S154 WeakPolarHBondContact CB-OG 3.4Å
35	A	93.7	Very high	92.1	Very high	0 Å²	0	11 Å²	11	0%	0	5%	0.05	C	C	.	.	H	α-helix	trans	-79.2	-39.7	-177.6	0	0	0	0	0	112.2	G31 K38 A39 F157 L158	G31-A35 WeakPolarHBondContact O-CB 3.46Å; G31-A35 PolarHBondContact O-N 3Å; A35-K38 PolarHBondContact O-N 3.35Å; A35-K38 VanDerWaalsContact O-N 3.11Å; A35-A39 WeakPolarHBondContact O-CB 3.43Å; A35-A39 PolarHBondContact O-N 3.02Å; A35-F157 HydrophobicContact CB-CB 3.67Å; A35-L158 HydrophobicContact CB-CB 3.88Å
36	F	94	Very high	91.8	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-57.2	-46.9	-171.2	-168.6	-95.3	0	0	0	113	F32 K38 A39 V40 M65 M100 T120 L124 L161 L181 L185	F32-F36 WeakPolarHBondContact O-CB 3.22Å; F32-F36 PolarHBondContact O-N 2.82Å; F36-K38 PolarHBondContact O-N 2.94Å; F36-A39 PolarHBondContact O-N 3.12Å; F36-A39 VanDerWaalsContact O-N 3.16Å; F36-V40 HydrophobicContact CD1-CG2 3.84Å; F36-V40 HydrophobicContact CD2-CG2 4.49Å; F36-V40 HydrophobicContact CE1-CG2 3.46Å; F36-V40 VanDerWaalsContact CE1-CG2 3.46Å; F36-V40 HydrophobicContact CE2-CG2 4.15Å; F36-V40 HydrophobicContact CG-CG2 4.33Å; F36-V40 HydrophobicContact CZ-CG2 3.61Å; F36-V40 VanDerWaalsContact O-CG2 3.32Å; F36-V40 WeakPolarHBondContact O-CG2 3.39Å; F36-V40 PolarHBondContact O-N 2.96Å; F36-M65 HydrophobicContact CD1-SD 3.92Å; F36-M65 HydrophobicContact CE1-SD 4.3Å; F36-M100 HydrophobicContact CE1-CE 4.39Å; F36-M100 HydrophobicContact CE1-SD 3.73Å; F36-M100 HydrophobicContact CZ-CE 3.74Å; F36-M100 HydrophobicContact CZ-CG 4.2Å; F36-M100 HydrophobicContact CZ-SD 3.54Å; F36-M100 VanDerWaalsContact CZ-SD 3.54Å; F36-T120 HydrophobicContact CD1-CG2 4.49Å; F36-T120 HydrophobicContact CE1-CG2 4.14Å; F36-L124 HydrophobicContact CB-CD1 4.4Å; F36-L124 HydrophobicContact CD1-CD1 4.35Å; F36-L161 HydrophobicContact CD2-CD2 3.99Å; F36-L181 HydrophobicContact CE2-CB 4.03Å; F36-L181 HydrophobicContact CE2-CD1 4.09Å; F36-L181 HydrophobicContact CE2-CD2 4.19Å; F36-L181 HydrophobicContact CE2-CG 4.33Å; F36-L181 HydrophobicContact CZ-CB 4.32Å; F36-L181 HydrophobicContact CZ-CD1 4.32Å; F36-L185 HydrophobicContact CD1-CD1 4.37Å; F36-L185 HydrophobicContact CD2-CD1 4.07Å; F36-L185 HydrophobicContact CD2-CD2 4.05Å; F36-L185 HydrophobicContact CD2-CG 4.25Å; F36-L185 HydrophobicContact CE1-CD1 3.99Å; F36-L185 HydrophobicContact CE2-CD1 3.69Å; F36-L185 HydrophobicContact CE2-CD2 4.43Å; F36-L185 HydrophobicContact CE2-CG 4.13Å; F36-L185 HydrophobicContact CG-CD1 4.41Å; F36-L185 HydrophobicContact CG-CD2 4.31Å; F36-L185 HydrophobicContact CZ-CD1 3.65Å
37	P	92.6	Very high	91.7	Very high	1 Å²	1	11.7 Å²	11.7	1%	0.006	5%	0.053	C	C	.	.	H	α-helix	trans	-63.1	-29.5	-179.7	-23.5	35.5	0	0	0	114.7	S33 T41 M65 L66 L124	S33-P37 VanDerWaalsContact O-CD 3.28Å; S33-P37 WeakPolarHBondContact O-CD 3.49Å; P37-T41 WeakPolarHBondContact O-CG2 3.4Å; P37-M65 VanDerWaalsContact CA-CE 3.45Å; P37-M65 HydrophobicContact CB-CE 3.7Å; P37-M65 HydrophobicContact CB-CG 4.27Å; P37-M65 HydrophobicContact CB-SD 4.04Å; P37-M65 HydrophobicContact CG-CE 4.24Å; P37-M65 HydrophobicContact CG-CG 4.02Å; P37-M65 HydrophobicContact CG-SD 3.9Å; P37-L66 HydrophobicContact CB-CD1 3.31Å; P37-L66 HydrophobicContact CB-CG 4.17Å; P37-L66 HydrophobicContact CG-CD1 4.16Å; P37-L124 HydrophobicContact CG-CD1 3.96Å
38	K	91.9	Very high	91.5	Very high	10 Å²	10	11 Å²	11	4%	0.043	5%	0.05	C	C	.	.	H	α-helix	trans	-81.7	-35.5	177.3	-61.1	163.2	-172.3	-80.8	0	111.2	A35 F36 T41 L158 I265 F351	A35-K38 PolarHBondContact O-N 3.35Å; A35-K38 VanDerWaalsContact O-N 3.11Å; F36-K38 PolarHBondContact O-N 2.94Å; K38-T41 WeakPolarHBondContact O-CG2 3.46Å; K38-T41 PolarHBondContact O-N 3.29Å; K38-T41 PolarHBondContact O-OG1 3.41Å; K38-L158 HydrophobicContact CB-CD1 3.75Å; K38-L158 HydrophobicContact CB-CD2 4.26Å; K38-L158 HydrophobicContact CD-CD2 3.81Å; K38-I265 HydrophobicContact CD-CD1 3.78Å; K38-I265 HydrophobicContact CG-CD1 4.2Å; K38-F351 VanDerWaalsContact NZ-CZ 3.26Å
39	A	93	Very high	91.3	Very high	0 Å²	0	15 Å²	15	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-75.1	-27.5	-179.6	0	0	0	0	0	112.7	A35 F36 T41 V42 L158 L161 N165	A35-A39 WeakPolarHBondContact O-CB 3.43Å; A35-A39 PolarHBondContact O-N 3.02Å; F36-A39 PolarHBondContact O-N 3.12Å; F36-A39 VanDerWaalsContact O-N 3.16Å; A39-T41 PolarHBondContact O-N 3.32Å; A39-V42 WeakPolarHBondContact O-CG2 3.26Å; A39-V42 PolarHBondContact O-N 3.45Å; A39-L158 HydrophobicContact CB-CD1 4.08Å; A39-L161 HydrophobicContact CB-CB 4.06Å; A39-L161 HydrophobicContact CB-CD2 3.63Å; A39-L161 HydrophobicContact CB-CG 3.74Å; A39-N165 PolarHBondContact O-ND2 3.37Å
40	V	91.1	Very high	91.1	Very high	1 Å²	1	19 Å²	19	1%	0.006	9%	0.088	C	C	.	.	G	3₁₀ helix	trans	-68.1	-19.3	175.7	170.7	0	0	0	0	112	F36 V42 F43 F44 V116	F36-V40 HydrophobicContact CD1-CG2 3.84Å; F36-V40 HydrophobicContact CD2-CG2 4.49Å; F36-V40 HydrophobicContact CE1-CG2 3.46Å; F36-V40 VanDerWaalsContact CE1-CG2 3.46Å; F36-V40 HydrophobicContact CE2-CG2 4.15Å; F36-V40 HydrophobicContact CG-CG2 4.33Å; F36-V40 HydrophobicContact CZ-CG2 3.61Å; F36-V40 VanDerWaalsContact O-CG2 3.32Å; F36-V40 WeakPolarHBondContact O-CG2 3.39Å; F36-V40 PolarHBondContact O-N 2.96Å; V40-V42 PolarHBondContact O-N 3Å; V40-V42 VanDerWaalsContact O-N 3.15Å; V40-F43 HydrophobicContact CG1-CD2 4.37Å; V40-F43 WeakPolarHBondContact O-CD2 3.25Å; V40-F43 PolarHBondContact O-N 2.82Å; V40-F43 VanDerWaalsContact O-N 3.11Å; V40-F44 HydrophobicContact CG1-CE1 3.93Å; V40-V116 HydrophobicContact CG1-CG1 4.44Å
41	T	90.6	Very high	91.1	Very high	0 Å²	0	21.1 Å²	21.1	0%	0	10%	0.098	C	C	.	.	G	3₁₀ helix	trans	-67.7	-15.9	179.8	75.1	0	0	0	0	113.2	P37 K38 A39 F43 F44 I266	P37-T41 WeakPolarHBondContact O-CG2 3.4Å; K38-T41 WeakPolarHBondContact O-CG2 3.46Å; K38-T41 PolarHBondContact O-N 3.29Å; K38-T41 PolarHBondContact O-OG1 3.41Å; A39-T41 PolarHBondContact O-N 3.32Å; T41-F43 PolarHBondContact O-N 3.04Å; T41-F44 HydrophobicContact CG2-CD2 4.01Å; T41-F44 HydrophobicContact CG2-CE2 3.63Å; T41-F44 HydrophobicContact CG2-CZ 4.04Å; T41-F44 VanDerWaalsContact O-CB 3.25Å; T41-F44 WeakPolarHBondContact O-CB 3.39Å; T41-F44 PolarHBondContact O-N 3.25Å; T41-F44 VanDerWaalsContact O-N 3.1Å; T41-I266 WeakPolarHBondContact CB-O 3.42Å; T41-I266 HydrophobicContact CG2-CB 4.22Å; T41-I266 HydrophobicContact CG2-CG1 4.17Å; T41-I266 HydrophobicContact CG2-CG2 3.9Å; T41-I266 PolarHBondContact OG1-O 3.18Å
42	V	91.3	Very high	91	Very high	2 Å²	2	29.2 Å²	29.2	1%	0.012	14%	0.135	C	C	.	.	G	3₁₀ helix	trans	-59.4	-32.2	172.5	176.3	0	0	0	0	111.8	A39 V40 A162 Q166 K273 A283 L286	A39-V42 WeakPolarHBondContact O-CG2 3.26Å; A39-V42 PolarHBondContact O-N 3.45Å; V40-V42 PolarHBondContact O-N 3Å; V40-V42 VanDerWaalsContact O-N 3.15Å; V42-A162 HydrophobicContact CG2-CB 4.46Å; V42-Q166 HydrophobicContact CG1-CB 4.04Å; V42-K273 PolarHBondContact O-NZ 3.41Å; V42-A283 HydrophobicContact CG1-CB 4.43Å; V42-A283 HydrophobicContact CG2-CB 4.39Å; V42-L286 HydrophobicContact CG2-CD1 3.97Å
43	F	91	Very high	91	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	14%	0.139	C	C	.	.	G	3₁₀ helix	trans	-83.2	-7.7	178.6	-56.7	-75.9	0	0	0	113.8	V40 T41 E46 I47 N165 F169 W174 F178 L181	V40-F43 HydrophobicContact CG1-CD2 4.37Å; V40-F43 WeakPolarHBondContact O-CD2 3.25Å; V40-F43 PolarHBondContact O-N 2.82Å; V40-F43 VanDerWaalsContact O-N 3.11Å; T41-F43 PolarHBondContact O-N 3.04Å; F43-E46 PolarHBondContact O-N 3.48Å; F43-I47 HydrophobicContact CB-CD1 3.98Å; F43-I47 HydrophobicContact CB-CG1 4.47Å; F43-I47 WeakPolarHBondContact O-CB 3.47Å; F43-I47 VanDerWaalsContact O-CG1 3.26Å; F43-I47 WeakPolarHBondContact O-CG1 3.42Å; F43-I47 PolarHBondContact O-N 3.35Å; F43-N165 HydrophobicContact CE2-CB 3.83Å; F43-N165 HydrophobicContact CZ-CB 3.7Å; F43-F169 HydrophobicContact CD1-CB 4.01Å; F43-F169 AromaticContact CD1-CD2 3.65Å; F43-F169 HydrophobicContact CD1-CD2 3.65Å; F43-F169 HydrophobicContact CD1-CG 4.09Å; F43-F169 HydrophobicContact CE1-CB 3.68Å; F43-F169 HydrophobicContact CE1-CD2 4.01Å; F43-F169 HydrophobicContact CE1-CG 4.23Å; F43-W174 HydrophobicContact CD1-CB 4.5Å; F43-F178 AromaticContact CD2-CE1 3.9Å; F43-F178 HydrophobicContact CD2-CE1 3.9Å; F43-F178 HydrophobicContact CE2-CE1 4.08Å; F43-F178 HydrophobicContact CG-CE1 4.31Å; F43-L181 HydrophobicContact CE2-CD1 3.89Å; F43-L181 HydrophobicContact CZ-CD1 4.08Å
44	F	88.3	Confident	91	Very high	5 Å²	5	32.5 Å²	32.5	2%	0.022	16%	0.156	C	C	.	.	H	α-helix	trans	-66.7	-42	-167.7	-79.2	3.3	0	0	0	112.7	V40 T41 E46 I47 Q48 I58 I61 S62 I266 P270	V40-F44 HydrophobicContact CG1-CE1 3.93Å; T41-F44 HydrophobicContact CG2-CD2 4.01Å; T41-F44 HydrophobicContact CG2-CE2 3.63Å; T41-F44 HydrophobicContact CG2-CZ 4.04Å; T41-F44 VanDerWaalsContact O-CB 3.25Å; T41-F44 WeakPolarHBondContact O-CB 3.39Å; T41-F44 PolarHBondContact O-N 3.25Å; T41-F44 VanDerWaalsContact O-N 3.1Å; F44-E46 VanDerWaalsContact C-N 3.28Å; F44-E46 PolarHBondContact O-N 3.17Å; F44-I47 PolarHBondContact O-N 2.79Å; F44-Q48 WeakPolarHBondContact O-CB 3.46Å; F44-Q48 PolarHBondContact O-N 2.92Å; F44-I58 HydrophobicContact CB-CG2 3.45Å; F44-I58 VanDerWaalsContact CB-CG2 3.45Å; F44-I58 HydrophobicContact CD1-CG2 3.64Å; F44-I58 HydrophobicContact CD2-CG2 3.56Å; F44-I58 HydrophobicContact CE1-CG2 4.18Å; F44-I58 HydrophobicContact CE2-CG2 4.11Å; F44-I58 HydrophobicContact CG-CG2 3.27Å; F44-I58 HydrophobicContact CZ-CG2 4.39Å; F44-I58 WeakPolarHBondContact O-CD1 3.2Å; F44-I61 HydrophobicContact CE1-CB 4.34Å; F44-I61 HydrophobicContact CE1-CG2 4.44Å; F44-I61 HydrophobicContact CZ-CB 4.21Å; F44-S62 WeakPolarHBondContact CE2-OG 3.25Å; F44-I266 HydrophobicContact CD2-CG2 4.29Å; F44-I266 HydrophobicContact CE2-CG2 3.94Å; F44-P270 HydrophobicContact CB-CG 4.43Å
45	K	88	Confident	91	Very high	56 Å²	56	32.7 Å²	32.7	24%	0.243	16%	0.157	C	C	.	.	H	α-helix	trans	-62.9	-38.3	-179.7	-174.4	171.8	179.5	169.2	0	111.3	Q48 Q49 K273	K45-Q48 WeakPolarHBondContact O-CB 3.22Å; K45-Q48 PolarHBondContact O-N 3.07Å; K45-Q49 PolarHBondContact O-N 3.36Å; K45-K273 HydrophobicContact CB-CD 4.27Å; K45-K273 HydrophobicContact CD-CB 3.43Å; K45-K273 VanDerWaalsContact CD-CB 3.43Å; K45-K273 HydrophobicContact CD-CD 3.88Å; K45-K273 HydrophobicContact CD-CG 4.28Å; K45-K273 PolarHBondContact NZ-O 3.45Å
46	E	88.1	Confident	91	Very high	14 Å²	14	33.6 Å²	33.6	7%	0.065	16%	0.163	C	C	.	.	H	α-helix	trans	-78.9	-38.4	-178	-60.5	89.8	171.6	0	0	112	F43 F44 Q48 Q49 I50 F169 K273	F43-E46 PolarHBondContact O-N 3.48Å; F44-E46 VanDerWaalsContact C-N 3.28Å; F44-E46 PolarHBondContact O-N 3.17Å; E46-Q48 PolarHBondContact O-N 2.88Å; E46-Q49 PolarHBondContact O-N 3.38Å; E46-I50 VanDerWaalsContact O-CG1 3.26Å; E46-I50 WeakPolarHBondContact O-CG1 3.49Å; E46-I50 PolarHBondContact O-N 2.85Å; E46-F169 HydrophobicContact CB-CE1 4.09Å; E46-F169 HydrophobicContact CB-CE2 3.88Å; E46-F169 HydrophobicContact CB-CZ 3.4Å; E46-F169 VanDerWaalsContact CB-CZ 3.4Å; E46-F169 HydrophobicContact CG-CD1 4.48Å; E46-F169 HydrophobicContact CG-CE1 3.54Å; E46-F169 HydrophobicContact CG-CE2 4.25Å; E46-F169 HydrophobicContact CG-CZ 3.4Å; E46-F169 VanDerWaalsContact CG-CZ 3.4Å; E46-K273 IonicContact OE1-NZ 2.63Å; E46-K273 PolarHBondContact OE1-NZ 3.11Å; E46-K273 IonicContact OE2-NZ 3.53Å
47	I	89.4	Confident	90.9	Very high	2 Å²	2	37.2 Å²	37.2	1%	0.01	18%	0.18	C	C	.	.	H	α-helix	trans	-58.5	-38.2	170	-72	174.3	0	0	0	110.1	F43 F44 Q49 I50 F51 L112 F178	F43-I47 HydrophobicContact CB-CD1 3.98Å; F43-I47 HydrophobicContact CB-CG1 4.47Å; F43-I47 WeakPolarHBondContact O-CB 3.47Å; F43-I47 VanDerWaalsContact O-CG1 3.26Å; F43-I47 WeakPolarHBondContact O-CG1 3.42Å; F43-I47 PolarHBondContact O-N 3.35Å; F44-I47 PolarHBondContact O-N 2.79Å; I47-Q49 PolarHBondContact O-N 3.05Å; I47-I50 PolarHBondContact O-N 3.32Å; I47-F51 HydrophobicContact CG2-CD2 3.73Å; I47-F51 HydrophobicContact CG2-CE2 4.13Å; I47-F51 WeakPolarHBondContact O-CD2 3.35Å; I47-F51 PolarHBondContact O-N 2.75Å; I47-L112 HydrophobicContact CG2-CD1 4.14Å; I47-F178 HydrophobicContact CD1-CE2 4.46Å; I47-F178 HydrophobicContact CD1-CZ 4.02Å
48	Q	89.4	Confident	90.9	Very high	29 Å²	29	37.3 Å²	37.3	14%	0.136	18%	0.181	C	C	.	.	H	α-helix	trans	-58.4	-47.9	174.2	-160.6	169.6	-1.4	0	0	113	F44 K45 E46 I50 H52 T53 Y55 I58	F44-Q48 WeakPolarHBondContact O-CB 3.46Å; F44-Q48 PolarHBondContact O-N 2.92Å; K45-Q48 WeakPolarHBondContact O-CB 3.22Å; K45-Q48 PolarHBondContact O-N 3.07Å; E46-Q48 PolarHBondContact O-N 2.88Å; Q48-I50 VanDerWaalsContact C-N 3.34Å; Q48-H52 VanDerWaalsContact O-CA 3.27Å; Q48-H52 WeakPolarHBondContact O-CA 3.48Å; Q48-H52 PolarHBondContact O-N 3.25Å; Q48-T53 WeakPolarHBondContact CG-O 3.3Å; Q48-T53 PolarHBondContact NE2-O 3.38Å; Q48-T53 PolarHBondContact O-N 3.37Å; Q48-Y55 VanDerWaalsContact NE2-CD1 3.31Å; Q48-Y55 VanDerWaalsContact NE2-CE1 3.34Å; Q48-I58 HydrophobicContact CB-CD1 3.09Å; Q48-I58 HydrophobicContact CG-CD1 3.38Å
49	Q	89.1	Confident	91	Very high	141 Å²	141	36.9 Å²	36.9	66%	0.659	18%	0.178	S	C	*	.	H	α-helix	trans	-68.9	-36.3	-177	-169.7	173.5	-8.6	0	0	111.5	K45 E46 I47 H52	K45-Q49 PolarHBondContact O-N 3.36Å; E46-Q49 PolarHBondContact O-N 3.38Å; I47-Q49 PolarHBondContact O-N 3.05Å; Q49-H52 PolarHBondContact O-CE1 3.04Å
50	I	90.4	Very high	91.2	Very high	84 Å²	84	40.6 Å²	40.6	43%	0.431	19%	0.193	S	C	.	.	H	α-helix	trans	-72.6	-42.6	-179.9	-68.6	168.6	0	0	0	111.9	E46 I47 Q48	E46-I50 VanDerWaalsContact O-CG1 3.26Å; E46-I50 WeakPolarHBondContact O-CG1 3.49Å; E46-I50 PolarHBondContact O-N 2.85Å; I47-I50 PolarHBondContact O-N 3.32Å; Q48-I50 VanDerWaalsContact C-N 3.34Å
51	F	91.5	Very high	91.3	Very high	46 Å²	46	40.7 Å²	40.7	20%	0.202	19%	0.193	C	C	.	.	H	α-helix	trans	-95.8	0.1	-177.2	-67.4	-68.8	0	0	0	113.8	I47 T53 S107 V109 L112 W174	I47-F51 HydrophobicContact CG2-CD2 3.73Å; I47-F51 HydrophobicContact CG2-CE2 4.13Å; I47-F51 WeakPolarHBondContact O-CD2 3.35Å; I47-F51 PolarHBondContact O-N 2.75Å; F51-T53 VanDerWaalsContact C-N 3.28Å; F51-T53 HydrophobicContact CB-CG2 4.01Å; F51-T53 PolarHBondContact O-N 3.13Å; F51-S107 VanDerWaalsContact CE1-O 3.29Å; F51-S107 WeakPolarHBondContact CE1-O 3.37Å; F51-V109 HydrophobicContact CB-CG2 3.65Å; F51-V109 HydrophobicContact CD1-CG2 4.39Å; F51-V109 HydrophobicContact CD2-CG2 3.99Å; F51-V109 HydrophobicContact CG-CG2 3.76Å; F51-L112 HydrophobicContact CE2-CD1 4.02Å; F51-W174 HydrophobicContact CE2-CH2 4.08Å; F51-W174 AromaticContact CE2-CZ2 3.95Å; F51-W174 HydrophobicContact CE2-CZ2 3.95Å; F51-W174 AromaticContact CZ-CH2 3.82Å; F51-W174 HydrophobicContact CZ-CH2 3.82Å; F51-W174 AromaticContact CZ-CZ2 3.74Å; F51-W174 HydrophobicContact CZ-CZ2 3.74Å
52	H	90.9	Very high	91.4	Very high	170 Å²	170	40.7 Å²	40.7	79%	0.787	19%	0.193	S	C	*	.	T	Hydrogen-bonded Turn	trans	51	44.9	-177.5	-59.4	-67.3	0	0	0	113.4	Q48 Q49	Q48-H52 VanDerWaalsContact O-CA 3.27Å; Q48-H52 WeakPolarHBondContact O-CA 3.48Å; Q48-H52 PolarHBondContact O-N 3.25Å; Q49-H52 PolarHBondContact O-CE1 3.04Å
53	T	92.1	Very high	91.6	Very high	22 Å²	22	40.6 Å²	40.6	14%	0.135	19%	0.193	C	C	.	.			trans	-102.3	169	-177.1	50.7	0	0	0	0	113.2	Q48 F51 E57 V109	Q48-T53 WeakPolarHBondContact CG-O 3.3Å; Q48-T53 PolarHBondContact NE2-O 3.38Å; Q48-T53 PolarHBondContact O-N 3.37Å; F51-T53 VanDerWaalsContact C-N 3.28Å; F51-T53 HydrophobicContact CB-CG2 4.01Å; F51-T53 PolarHBondContact O-N 3.13Å; T53-E57 WeakPolarHBondContact CA-OE2 3.45Å; T53-E57 VanDerWaalsContact CB-OE2 3.26Å; T53-E57 WeakPolarHBondContact CB-OE2 3.41Å; T53-V109 HydrophobicContact CG2-CB 4.49Å; T53-V109 HydrophobicContact CG2-CG2 3.66Å
54	T	93.3	Very high	91.9	Very high	58 Å²	58	42.1 Å²	42.1	36%	0.356	20%	0.2	S	C	.	.			trans	-83.1	161.1	177.5	59.1	0	0	0	0	112.1	S56 E57 I58 D398	T54-S56 VanDerWaalsContact C-N 3.27Å; T54-S56 PolarHBondContact O-N 3.37Å; T54-E57 PolarHBondContact N-OE2 3.15Å; T54-E57 PolarHBondContact O-N 3.47Å; T54-E57 VanDerWaalsContact OG1-CD 3.28Å; T54-E57 WeakPolarHBondContact OG1-CG 3.41Å; T54-E57 PolarHBondContact OG1-N 3.29Å; T54-E57 PolarHBondContact OG1-OE2 2.99Å; T54-I58 PolarHBondContact O-N 3.2Å; T54-D398 WeakPolarHBondContact CB-OD1 3.17Å
55	Y	90.7	Very high	92.2	Very high	46 Å²	46	41.9 Å²	41.9	18%	0.18	20%	0.199	C	C	.	.	H	α-helix	trans	-61.4	-37.7	175.1	-65.8	-67.6	0	0	0	111.5	Q48 I58 A59 V397 D398 Y403	Q48-Y55 VanDerWaalsContact NE2-CD1 3.31Å; Q48-Y55 VanDerWaalsContact NE2-CE1 3.34Å; Y55-I58 PolarHBondContact O-N 3.48Å; Y55-A59 WeakPolarHBondContact O-CB 3.4Å; Y55-A59 PolarHBondContact O-N 2.85Å; Y55-V397 HydrophobicContact CD2-CB 4.15Å; Y55-V397 HydrophobicContact CD2-CG1 3.69Å; Y55-V397 HydrophobicContact CE2-CG1 3.85Å; Y55-V397 HydrophobicContact CG-CG1 4.3Å; Y55-D398 VanDerWaalsContact CB-OD1 3.31Å; Y55-D398 WeakPolarHBondContact CB-OD1 3.4Å; Y55-D398 WeakPolarHBondContact CD2-OD1 3.25Å; Y55-D398 PolarHBondContact N-OD1 3.31Å; Y55-D398 PolarHBondContact N-OD2 2.79Å; Y55-Y403 VanDerWaalsContact CD1-OH 3.29Å; Y55-Y403 WeakPolarHBondContact CD1-OH 3.35Å; Y55-Y403 HydrophobicContact CE1-CE2 4.34Å; Y55-Y403 AromaticContact CE1-CZ 3.84Å; Y55-Y403 WeakPolarHBondContact CE1-OH 3.32Å
56	S	93.6	Very high	92.5	Very high	19 Å²	19	39.6 Å²	39.6	13%	0.133	19%	0.19	C	C	.	.	H	α-helix	trans	-58.3	-47.7	173.9	173.9	0	0	0	0	112.3	T54 I58 A59 W60 P391 D398	T54-S56 VanDerWaalsContact C-N 3.27Å; T54-S56 PolarHBondContact O-N 3.37Å; S56-I58 VanDerWaalsContact C-N 3.33Å; S56-I58 PolarHBondContact O-N 3.34Å; S56-A59 PolarHBondContact O-N 3.49Å; S56-W60 PolarHBondContact O-N 3.29Å; S56-P391 PolarHBondContact OG-O 3.48Å; S56-D398 WeakPolarHBondContact CB-OD2 3.4Å; S56-D398 PolarHBondContact N-OD2 2.81Å
57	E	93.5	Very high	92.9	Very high	75 Å²	75	39 Å²	39	35%	0.35	19%	0.188	S	C	.	.	H	α-helix	trans	-59.6	-44.2	179.8	-77.4	168.1	141.4	0	0	111.4	T53 T54 A59 W60 Y113	T53-E57 WeakPolarHBondContact CA-OE2 3.45Å; T53-E57 VanDerWaalsContact CB-OE2 3.26Å; T53-E57 WeakPolarHBondContact CB-OE2 3.41Å; T54-E57 PolarHBondContact N-OE2 3.15Å; T54-E57 PolarHBondContact O-N 3.47Å; T54-E57 VanDerWaalsContact OG1-CD 3.28Å; T54-E57 WeakPolarHBondContact OG1-CG 3.41Å; T54-E57 PolarHBondContact OG1-N 3.29Å; T54-E57 PolarHBondContact OG1-OE2 2.99Å; E57-A59 PolarHBondContact O-N 3.25Å; E57-W60 WeakPolarHBondContact O-CB 3.31Å; E57-W60 PolarHBondContact O-N 3.42Å; E57-Y113 WeakPolarHBondContact CA-OH 3.47Å; E57-Y113 WeakPolarHBondContact CB-OH 3.44Å; E57-Y113 VanDerWaalsContact O-CE1 3.23Å; E57-Y113 WeakPolarHBondContact O-CE1 3.31Å; E57-Y113 PolarHBondContact O-OH 3.35Å
58	I	92.5	Very high	93.2	Very high	4 Å²	4	40 Å²	40	2%	0.021	19%	0.194	C	C	.	.	H	α-helix	trans	-72	-35.6	-177.8	-65.4	171.7	0	0	0	112.1	F44 Q48 T54 Y55 S56 W60 I61	F44-I58 HydrophobicContact CB-CG2 3.45Å; F44-I58 VanDerWaalsContact CB-CG2 3.45Å; F44-I58 HydrophobicContact CD1-CG2 3.64Å; F44-I58 HydrophobicContact CD2-CG2 3.56Å; F44-I58 HydrophobicContact CE1-CG2 4.18Å; F44-I58 HydrophobicContact CE2-CG2 4.11Å; F44-I58 HydrophobicContact CG-CG2 3.27Å; F44-I58 HydrophobicContact CZ-CG2 4.39Å; F44-I58 WeakPolarHBondContact O-CD1 3.2Å; Q48-I58 HydrophobicContact CB-CD1 3.09Å; Q48-I58 HydrophobicContact CG-CD1 3.38Å; T54-I58 PolarHBondContact O-N 3.2Å; Y55-I58 PolarHBondContact O-N 3.48Å; S56-I58 VanDerWaalsContact C-N 3.33Å; S56-I58 PolarHBondContact O-N 3.34Å; I58-W60 PolarHBondContact O-N 2.98Å; I58-I61 HydrophobicContact CG2-CD1 4.5Å; I58-I61 WeakPolarHBondContact O-CB 3.44Å; I58-I61 WeakPolarHBondContact O-CG1 3.48Å; I58-I61 PolarHBondContact O-N 3.25Å
59	A	93.8	Very high	93.4	Very high	0 Å²	0	38.9 Å²	38.9	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-58.9	-31.4	176	0	0	0	0	0	112.6	Y55 S56 E57 I61 S62 S63 F267 P390 P391	Y55-A59 WeakPolarHBondContact O-CB 3.4Å; Y55-A59 PolarHBondContact O-N 2.85Å; S56-A59 PolarHBondContact O-N 3.49Å; E57-A59 PolarHBondContact O-N 3.25Å; A59-I61 PolarHBondContact O-N 3.4Å; A59-S62 PolarHBondContact O-N 3.01Å; A59-S62 PolarHBondContact O-OG 3.09Å; A59-S63 WeakPolarHBondContact O-CB 3.48Å; A59-S63 PolarHBondContact O-N 3.23Å; A59-S63 PolarHBondContact O-OG 3.21Å; A59-F267 HydrophobicContact CB-CE1 4.39Å; A59-F267 HydrophobicContact CB-CE2 4.31Å; A59-F267 HydrophobicContact CB-CZ 3.63Å; A59-P390 HydrophobicContact CB-CB 4.05Å; A59-P391 HydrophobicContact CB-CG 4.46Å
60	W	95.6	Very high	93.5	Very high	78 Å²	78	33.6 Å²	33.6	30%	0.295	16%	0.163	S	C	.	.	H	α-helix	trans	-56.7	-33.2	174.1	-79.6	106.1	0	0	0	112.7	S56 E57 I58 S63 I64 Y113 L387 L388 P391	S56-W60 PolarHBondContact O-N 3.29Å; E57-W60 WeakPolarHBondContact O-CB 3.31Å; E57-W60 PolarHBondContact O-N 3.42Å; I58-W60 PolarHBondContact O-N 2.98Å; W60-S63 PolarHBondContact O-N 2.91Å; W60-I64 HydrophobicContact CB-CD1 4.19Å; W60-I64 HydrophobicContact CE3-CD1 4.17Å; W60-I64 HydrophobicContact CE3-CG1 4.01Å; W60-I64 VanDerWaalsContact O-CB 3.28Å; W60-I64 WeakPolarHBondContact O-CB 3.21Å; W60-I64 WeakPolarHBondContact O-CD1 3.42Å; W60-I64 WeakPolarHBondContact O-CG1 3.45Å; W60-I64 PolarHBondContact O-N 3.46Å; W60-Y113 HydrophobicContact CB-CD1 4.17Å; W60-Y113 HydrophobicContact CB-CE1 3.58Å; W60-L387 HydrophobicContact CE3-CD1 4.07Å; W60-L387 HydrophobicContact CZ3-CD1 3.71Å; W60-L387 HydrophobicContact CZ3-CD2 4.44Å; W60-L387 HydrophobicContact CZ3-CG 3.79Å; W60-L388 HydrophobicContact CH2-CD2 4.04Å; W60-P391 HydrophobicContact CB-CG 4.46Å; W60-P391 HydrophobicContact CD2-CB 3.93Å; W60-P391 HydrophobicContact CD2-CG 3.48Å; W60-P391 VanDerWaalsContact CD2-CG 3.48Å; W60-P391 HydrophobicContact CE3-CG 3.9Å; W60-P391 HydrophobicContact CG-CB 4.13Å; W60-P391 HydrophobicContact CG-CG 3.75Å; W60-P391 HydrophobicContact CH2-CG 4.47Å; W60-P391 HydrophobicContact CZ2-CB 3.93Å; W60-P391 HydrophobicContact CZ2-CG 4.11Å; W60-P391 HydrophobicContact CZ3-CG 4.38Å
61	I	94.4	Very high	93.5	Very high	3 Å²	3	31.3 Å²	31.3	2%	0.015	16%	0.157	C	C	.	.	H	α-helix	trans	-59.4	-54.9	179.1	-56.2	173.5	0	0	0	110.2	F44 I58 A59 M65 L112 Y113 V116	F44-I61 HydrophobicContact CE1-CB 4.34Å; F44-I61 HydrophobicContact CE1-CG2 4.44Å; F44-I61 HydrophobicContact CZ-CB 4.21Å; I58-I61 HydrophobicContact CG2-CD1 4.5Å; I58-I61 WeakPolarHBondContact O-CB 3.44Å; I58-I61 WeakPolarHBondContact O-CG1 3.48Å; I58-I61 PolarHBondContact O-N 3.25Å; A59-I61 PolarHBondContact O-N 3.4Å; I61-M65 WeakPolarHBondContact O-CB 3.26Å; I61-M65 PolarHBondContact O-N 3.03Å; I61-M65 VanDerWaalsContact O-N 3.15Å; I61-L112 HydrophobicContact CD1-CB 4.15Å; I61-L112 HydrophobicContact CD1-CD1 4.29Å; I61-Y113 HydrophobicContact CG1-CD1 3.66Å; I61-Y113 HydrophobicContact CG1-CE1 3.64Å; I61-V116 HydrophobicContact CG2-CB 3.92Å; I61-V116 HydrophobicContact CG2-CG1 3.73Å
62	S	92.8	Very high	93.4	Very high	0 Å²	0	29.2 Å²	29.2	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-66.2	-39.5	178.2	52.7	0	0	0	0	112.4	F44 A59 M65 L66	F44-S62 WeakPolarHBondContact CE2-OG 3.25Å; A59-S62 PolarHBondContact O-N 3.01Å; A59-S62 PolarHBondContact O-OG 3.09Å; S62-M65 WeakPolarHBondContact O-CB 3.48Å; S62-M65 PolarHBondContact O-N 3.25Å; S62-L66 WeakPolarHBondContact O-CD1 3.46Å; S62-L66 PolarHBondContact O-N 3.37Å
63	S	95.3	Very high	93.2	Very high	1 Å²	1	21.5 Å²	21.5	1%	0.007	12%	0.115	C	C	.	.	H	α-helix	trans	-66.1	-44.7	-178.7	-82.7	0	0	0	0	113.1	A59 W60 M65 L66 A67 V386 L387 P390 P391	A59-S63 WeakPolarHBondContact O-CB 3.48Å; A59-S63 PolarHBondContact O-N 3.23Å; A59-S63 PolarHBondContact O-OG 3.21Å; W60-S63 PolarHBondContact O-N 2.91Å; S63-M65 VanDerWaalsContact C-N 3.29Å; S63-M65 PolarHBondContact O-N 3.43Å; S63-L66 PolarHBondContact O-N 3.41Å; S63-A67 WeakPolarHBondContact O-CB 3.38Å; S63-A67 PolarHBondContact O-N 3.33Å; S63-V386 PolarHBondContact OG-O 2.82Å; S63-L387 VanDerWaalsContact CB-O 3.28Å; S63-L387 WeakPolarHBondContact CB-O 3.43Å; S63-L387 PolarHBondContact OG-O 2.65Å; S63-P390 VanDerWaalsContact OG-CB 3.28Å; S63-P390 WeakPolarHBondContact OG-CB 3.26Å; S63-P390 WeakPolarHBondContact OG-CD 3.5Å; S63-P390 WeakPolarHBondContact OG-CG 3.49Å; S63-P391 VanDerWaalsContact OG-CD 3.27Å; S63-P391 WeakPolarHBondContact OG-CD 3.43Å
64	I	96.4	Very high	92.9	Very high	31 Å²	31	21.9 Å²	21.9	16%	0.159	12%	0.117	C	C	.	.	H	α-helix	trans	-61.5	-43.3	174.4	-65.8	164.8	0	0	0	109.1	W60 A67 V68 Y113 F118 L387	W60-I64 HydrophobicContact CB-CD1 4.19Å; W60-I64 HydrophobicContact CE3-CD1 4.17Å; W60-I64 HydrophobicContact CE3-CG1 4.01Å; W60-I64 VanDerWaalsContact O-CB 3.28Å; W60-I64 WeakPolarHBondContact O-CB 3.21Å; W60-I64 WeakPolarHBondContact O-CD1 3.42Å; W60-I64 WeakPolarHBondContact O-CG1 3.45Å; W60-I64 PolarHBondContact O-N 3.46Å; I64-A67 PolarHBondContact O-N 2.99Å; I64-V68 HydrophobicContact CG2-CG2 4.01Å; I64-V68 WeakPolarHBondContact O-CB 2.87Å; I64-V68 WeakPolarHBondContact O-CG2 3.29Å; I64-V68 PolarHBondContact O-N 2.8Å; I64-Y113 HydrophobicContact CD1-CD1 4.17Å; I64-Y113 HydrophobicContact CD1-CG 4Å; I64-F118 HydrophobicContact CG2-CB 4.47Å; I64-L387 HydrophobicContact CB-CD1 4.43Å; I64-L387 HydrophobicContact CG1-CD1 3.79Å
65	M	95.9	Very high	92.7	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-60	-49.8	178.6	-174.6	170.7	27.1	0	0	112.8	F36 P37 I61 S62 S63 M69 V116 G117 L124	F36-M65 HydrophobicContact CD1-SD 3.92Å; F36-M65 HydrophobicContact CE1-SD 4.3Å; P37-M65 VanDerWaalsContact CA-CE 3.45Å; P37-M65 HydrophobicContact CB-CE 3.7Å; P37-M65 HydrophobicContact CB-CG 4.27Å; P37-M65 HydrophobicContact CB-SD 4.04Å; P37-M65 HydrophobicContact CG-CE 4.24Å; P37-M65 HydrophobicContact CG-CG 4.02Å; P37-M65 HydrophobicContact CG-SD 3.9Å; I61-M65 WeakPolarHBondContact O-CB 3.26Å; I61-M65 PolarHBondContact O-N 3.03Å; I61-M65 VanDerWaalsContact O-N 3.15Å; S62-M65 WeakPolarHBondContact O-CB 3.48Å; S62-M65 PolarHBondContact O-N 3.25Å; S63-M65 VanDerWaalsContact C-N 3.29Å; S63-M65 PolarHBondContact O-N 3.43Å; M65-M69 VanDerWaalsContact O-CB 3.32Å; M65-M69 WeakPolarHBondContact O-CB 3.38Å; M65-M69 PolarHBondContact O-N 3.26Å; M65-V116 HydrophobicContact CE-CG1 4.13Å; M65-V116 HydrophobicContact SD-CG1 4.42Å; M65-G117 WeakPolarHBondContact CA-O 3.22Å; M65-L124 HydrophobicContact CG-CD1 4.27Å; M65-L124 HydrophobicContact SD-CD1 4.11Å
66	L	94	Very high	92.6	Very high	8 Å²	8	21.2 Å²	21.2	4%	0.042	11%	0.114	C	C	.	.	H	α-helix	trans	-65.7	-43.3	176.3	-85.4	86.9	0	0	0	111.7	P37 S62 S63 M69 Y70 F262 V386	P37-L66 HydrophobicContact CB-CD1 3.31Å; P37-L66 HydrophobicContact CB-CG 4.17Å; P37-L66 HydrophobicContact CG-CD1 4.16Å; S62-L66 WeakPolarHBondContact O-CD1 3.46Å; S62-L66 PolarHBondContact O-N 3.37Å; S63-L66 PolarHBondContact O-N 3.41Å; L66-M69 WeakPolarHBondContact O-CB 3.35Å; L66-M69 PolarHBondContact O-N 3.27Å; L66-Y70 WeakPolarHBondContact O-CD1 3.35Å; L66-Y70 PolarHBondContact O-N 2.87Å; L66-F262 HydrophobicContact CD2-CD1 3.8Å; L66-F262 HydrophobicContact CD2-CD2 4.15Å; L66-F262 HydrophobicContact CD2-CE1 3.81Å; L66-F262 HydrophobicContact CD2-CE2 4.12Å; L66-F262 HydrophobicContact CD2-CG 3.98Å; L66-F262 HydrophobicContact CD2-CZ 3.98Å; L66-V386 HydrophobicContact CB-CG1 3.52Å; L66-V386 HydrophobicContact CD2-CG1 4.06Å; L66-V386 HydrophobicContact CG-CG1 4.44Å
67	A	95.4	Very high	92.2	Very high	3 Å²	3	21.7 Å²	21.7	3%	0.025	12%	0.117	C	C	.	.	H	α-helix	trans	-60.6	-48.5	-178.9	0	0	0	0	0	111.4	S63 I64 M69 Y70 A71 C383 L387	S63-A67 WeakPolarHBondContact O-CB 3.38Å; S63-A67 PolarHBondContact O-N 3.33Å; I64-A67 PolarHBondContact O-N 2.99Å; A67-M69 VanDerWaalsContact C-N 3.31Å; A67-M69 PolarHBondContact O-N 3.32Å; A67-Y70 PolarHBondContact O-N 3.33Å; A67-A71 VanDerWaalsContact O-CB 3.31Å; A67-A71 WeakPolarHBondContact O-CB 3.13Å; A67-A71 PolarHBondContact O-N 2.63Å; A67-C383 PolarHBondContact O-SG 3.46Å; A67-C383 VanDerWaalsContact O-SG 3.36Å; A67-L387 HydrophobicContact CB-CB 3.77Å; A67-L387 HydrophobicContact CB-CD1 3.81Å; A67-L387 HydrophobicContact CB-CG 4.29Å
68	V	95.9	Very high	91.7	Very high	23 Å²	23	21.4 Å²	21.4	14%	0.139	12%	0.12	C	C	.	.	H	α-helix	trans	-64.8	-37.3	176.5	176.7	0	0	0	0	110.8	I64 Y70 G72 F118 L122	I64-V68 HydrophobicContact CG2-CG2 4.01Å; I64-V68 WeakPolarHBondContact O-CB 2.87Å; I64-V68 WeakPolarHBondContact O-CG2 3.29Å; I64-V68 PolarHBondContact O-N 2.8Å; V68-Y70 VanDerWaalsContact C-N 3.33Å; V68-Y70 PolarHBondContact O-N 3.37Å; V68-G72 WeakPolarHBondContact O-CA 3.21Å; V68-G72 PolarHBondContact O-N 3.45Å; V68-F118 HydrophobicContact CG1-CD2 4.26Å; V68-F118 HydrophobicContact CG2-CD2 3.75Å; V68-F118 HydrophobicContact CG2-CE2 4.39Å; V68-L122 HydrophobicContact CG1-CB 3.91Å
69	M	94.3	Very high	91.4	Very high	5 Å²	5	23.7 Å²	23.7	3%	0.025	13%	0.132	C	C	.	.	H	α-helix	trans	-59.2	-44	174.2	-175.1	-178.8	71.4	0	0	112	Y34 M65 L66 A67 L124 A125 L128	Y34-M69 HydrophobicContact CD1-CE 3.97Å; Y34-M69 HydrophobicContact CE1-CE 3.97Å; M65-M69 VanDerWaalsContact O-CB 3.32Å; M65-M69 WeakPolarHBondContact O-CB 3.38Å; M65-M69 PolarHBondContact O-N 3.26Å; L66-M69 WeakPolarHBondContact O-CB 3.35Å; L66-M69 PolarHBondContact O-N 3.27Å; A67-M69 VanDerWaalsContact C-N 3.31Å; A67-M69 PolarHBondContact O-N 3.32Å; M69-L124 HydrophobicContact CG-CB 4.21Å; M69-L124 HydrophobicContact SD-CB 4.11Å; M69-A125 WeakPolarHBondContact O-CB 3.31Å; M69-L128 HydrophobicContact CE-CD2 4.44Å; M69-L128 HydrophobicContact CG-CD2 4.33Å; M69-L128 HydrophobicContact SD-CD2 4.18Å
70	Y	91.1	Very high	91	Very high	29 Å²	29	23.8 Å²	23.8	11%	0.114	13%	0.133	C	C	.	.	H	α-helix	trans	-74.4	-45.7	-178.4	-81.9	50.7	0	0	0	111.7	Y34 L66 A67 V68 G72 G73	Y34-Y70 HydrophobicContact CE1-CE1 4.38Å; L66-Y70 WeakPolarHBondContact O-CD1 3.35Å; L66-Y70 PolarHBondContact O-N 2.87Å; A67-Y70 PolarHBondContact O-N 3.33Å; V68-Y70 VanDerWaalsContact C-N 3.33Å; V68-Y70 PolarHBondContact O-N 3.37Å; Y70-G72 PolarHBondContact O-N 3.06Å; Y70-G73 PolarHBondContact O-N 3.17Å
71	A	91	Very high	90.3	Very high	37 Å²	37	23.9 Å²	23.9	31%	0.306	14%	0.139	S	C	.	.	H	α-helix	trans	-65.6	-28.2	176.4	0	0	0	0	0	112.7	A67 G73 P74 C383	A67-A71 VanDerWaalsContact O-CB 3.31Å; A67-A71 WeakPolarHBondContact O-CB 3.13Å; A67-A71 PolarHBondContact O-N 2.63Å; A71-G73 VanDerWaalsContact C-N 3.25Å; A71-G73 PolarHBondContact O-N 2.97Å; A71-P74 WeakPolarHBondContact O-CD 3.35Å; A71-C383 HydrophobicContact CB-CB 4.43Å
72	G	89.1	Confident	89.9	Confident	2 Å²	2	30.8 Å²	30.8	2%	0.021	17%	0.169	C	C	.	.	H	α-helix	trans	-71.5	-13.7	176.7	0	0	0	0	0	114.3	V68 Y70 I75 S76	V68-G72 WeakPolarHBondContact O-CA 3.21Å; V68-G72 PolarHBondContact O-N 3.45Å; Y70-G72 PolarHBondContact O-N 3.06Å; G72-I75 PolarHBondContact O-N 3.37Å; G72-S76 VanDerWaalsContact O-CB 3.26Å; G72-S76 WeakPolarHBondContact O-CB 3.32Å; G72-S76 PolarHBondContact O-N 3.42Å
73	G	87.1	Confident	89.5	Confident	8 Å²	8	37.3 Å²	37.3	8%	0.082	20%	0.195	C	C	.	.	H	α-helix	trans	-56.7	-56	-178.2	0	0	0	0	0	114.2	Y70 A71 I75 S76 S77	Y70-G73 PolarHBondContact O-N 3.17Å; A71-G73 VanDerWaalsContact C-N 3.25Å; A71-G73 PolarHBondContact O-N 2.97Å; G73-I75 VanDerWaalsContact C-N 3.33Å; G73-I75 PolarHBondContact O-N 3.41Å; G73-S76 PolarHBondContact O-N 3.43Å; G73-S77 PolarHBondContact O-N 3.18Å
74	P	84.9	Confident	89.1	Confident	30 Å²	30	38.6 Å²	38.6	20%	0.195	21%	0.208	C	C	.	.	H	α-helix	trans	-60.4	-39.1	176.4	-25.2	34	0	0	0	113.5	A71 S77 V78 V380	A71-P74 WeakPolarHBondContact O-CD 3.35Å; P74-S77 WeakPolarHBondContact O-CB 3.28Å; P74-S77 PolarHBondContact O-N 2.87Å; P74-V78 WeakPolarHBondContact O-CG2 3.45Å; P74-V78 PolarHBondContact O-N 3.06Å; P74-V380 HydrophobicContact CG-CG2 3.57Å
75	I	88.8	Confident	88.6	Confident	89 Å²	89	37.6 Å²	37.6	46%	0.456	20%	0.203	S	C	.	.	H	α-helix	trans	-61.1	-52.2	177	-63.8	168.6	0	0	0	109	G72 G73 S77 V78 L79 F126	G72-I75 PolarHBondContact O-N 3.37Å; G73-I75 VanDerWaalsContact C-N 3.33Å; G73-I75 PolarHBondContact O-N 3.41Å; I75-S77 VanDerWaalsContact C-N 3.29Å; I75-S77 PolarHBondContact O-N 3.08Å; I75-V78 PolarHBondContact O-N 3.12Å; I75-V78 VanDerWaalsContact O-N 3.11Å; I75-L79 HydrophobicContact CG2-CD1 3.67Å; I75-L79 WeakPolarHBondContact O-CD1 3.16Å; I75-L79 PolarHBondContact O-N 3.28Å; I75-F126 HydrophobicContact CG2-CE1 4.13Å; I75-F126 HydrophobicContact CG2-CZ 4.34Å
76	S	89.3	Confident	88.4	Confident	0 Å²	0	43 Å²	43	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-56.3	-42.1	176.8	-167.6	0	0	0	0	112	G72 G73 V78 L79 V80 A125 Q129	G72-S76 VanDerWaalsContact O-CB 3.26Å; G72-S76 WeakPolarHBondContact O-CB 3.32Å; G72-S76 PolarHBondContact O-N 3.42Å; G73-S76 PolarHBondContact O-N 3.43Å; S76-V78 PolarHBondContact O-N 3.5Å; S76-L79 PolarHBondContact O-N 3.35Å; S76-V80 WeakPolarHBondContact O-CB 3.44Å; S76-V80 VanDerWaalsContact O-CG2 3.26Å; S76-V80 WeakPolarHBondContact O-CG2 3.11Å; S76-V80 PolarHBondContact O-N 3.22Å; S76-A125 PolarHBondContact OG-O 3.25Å; S76-Q129 WeakPolarHBondContact OG-CB 3.48Å
77	S	84.4	Confident	88.3	Confident	29 Å²	29	46 Å²	46	20%	0.203	24%	0.244	C	C	.	.	H	α-helix	trans	-59.7	-44.1	175.8	-176.4	0	0	0	0	112.8	G73 P74 I75 V80 N81	G73-S77 PolarHBondContact O-N 3.18Å; P74-S77 WeakPolarHBondContact O-CB 3.28Å; P74-S77 PolarHBondContact O-N 2.87Å; I75-S77 VanDerWaalsContact C-N 3.29Å; I75-S77 PolarHBondContact O-N 3.08Å; S77-V80 PolarHBondContact O-N 2.9Å; S77-N81 VanDerWaalsContact O-CG 3.29Å; S77-N81 PolarHBondContact O-N 3.29Å; S77-N81 PolarHBondContact O-ND2 3.35Å; S77-N81 VanDerWaalsContact O-ND2 3.13Å
78	V	84.1	Confident	88.2	Confident	70 Å²	70	46.1 Å²	46.1	42%	0.424	24%	0.244	S	C	.	.	H	α-helix	trans	-64.1	-42	175.7	174.4	0	0	0	0	111.2	P74 I75 S76 N81 K82 Y236	P74-V78 WeakPolarHBondContact O-CG2 3.45Å; P74-V78 PolarHBondContact O-N 3.06Å; I75-V78 PolarHBondContact O-N 3.12Å; I75-V78 VanDerWaalsContact O-N 3.11Å; S76-V78 PolarHBondContact O-N 3.5Å; V78-N81 PolarHBondContact O-N 3.04Å; V78-K82 PolarHBondContact O-N 3.03Å; V78-Y236 HydrophobicContact CG2-CD2 4.28Å; V78-Y236 HydrophobicContact CG2-CE2 4.35Å
79	L	86.3	Confident	88.2	Confident	51 Å²	51	45 Å²	45	27%	0.267	24%	0.238	S	C	.	.	H	α-helix	trans	-63.7	-44.7	177.1	-86.8	80.6	0	0	0	111.7	I75 S76 N81 K82 Y83 V88 F126	I75-L79 HydrophobicContact CG2-CD1 3.67Å; I75-L79 WeakPolarHBondContact O-CD1 3.16Å; I75-L79 PolarHBondContact O-N 3.28Å; S76-L79 PolarHBondContact O-N 3.35Å; L79-N81 VanDerWaalsContact C-N 3.28Å; L79-N81 PolarHBondContact O-N 2.62Å; L79-K82 PolarHBondContact O-N 3.33Å; L79-K82 VanDerWaalsContact O-N 3.08Å; L79-Y83 PolarHBondContact O-N 3.27Å; L79-V88 HydrophobicContact CB-CG2 3.9Å; L79-F126 HydrophobicContact CD2-CE2 4.34Å; L79-F126 HydrophobicContact CD2-CZ 4.09Å
80	V	84.4	Confident	88.2	Confident	3 Å²	3	47.3 Å²	47.3	2%	0.018	25%	0.249	C	C	.	.	H	α-helix	trans	-61	-38.7	177.6	169.4	0	0	0	0	111.5	S76 S77 K82 G84 S85 V88 P130 T133	S76-V80 WeakPolarHBondContact O-CB 3.44Å; S76-V80 VanDerWaalsContact O-CG2 3.26Å; S76-V80 WeakPolarHBondContact O-CG2 3.11Å; S76-V80 PolarHBondContact O-N 3.22Å; S77-V80 PolarHBondContact O-N 2.9Å; V80-K82 VanDerWaalsContact C-N 3.28Å; V80-K82 PolarHBondContact O-N 3.38Å; V80-G84 CarbonylContact O-C 3.38Å; V80-G84 WeakPolarHBondContact O-CA 3.23Å; V80-G84 PolarHBondContact O-N 3.12Å; V80-S85 WeakPolarHBondContact CG1-OG 3.28Å; V80-V88 HydrophobicContact CG2-CB 4.09Å; V80-V88 HydrophobicContact CG2-CG1 4.11Å; V80-V88 HydrophobicContact CG2-CG2 4.04Å; V80-P130 HydrophobicContact CG2-CB 3.6Å; V80-P130 HydrophobicContact CG2-CG 3.46Å; V80-P130 VanDerWaalsContact CG2-CG 3.46Å; V80-T133 HydrophobicContact CG1-CG2 4.13Å
81	N	82	Confident	88.4	Confident	79 Å²	79	48.3 Å²	48.3	42%	0.422	26%	0.263	S	S	.	.	H	α-helix	trans	-68.4	-28.3	177.1	-73	-32	0	0	0	112.8	S77 V78 L79	S77-N81 VanDerWaalsContact O-CG 3.29Å; S77-N81 PolarHBondContact O-N 3.29Å; S77-N81 PolarHBondContact O-ND2 3.35Å; S77-N81 VanDerWaalsContact O-ND2 3.13Å; V78-N81 PolarHBondContact O-N 3.04Å; L79-N81 VanDerWaalsContact C-N 3.28Å; L79-N81 PolarHBondContact O-N 2.62Å
82	K	84.6	Confident	88.6	Confident	148 Å²	148	46.5 Å²	46.5	64%	0.643	25%	0.249	S	C	*	.	H	α-helix	trans	-89.2	-43.6	-179.5	-169.7	179.9	178.3	-161.9	0	113.1	V78 L79 V80	V78-K82 PolarHBondContact O-N 3.03Å; L79-K82 PolarHBondContact O-N 3.33Å; L79-K82 VanDerWaalsContact O-N 3.08Å; V80-K82 VanDerWaalsContact C-N 3.28Å; V80-K82 PolarHBondContact O-N 3.38Å
83	Y	85.9	Confident	88.9	Confident	138 Å²	138	46.4 Å²	46.4	54%	0.541	25%	0.248	S	C	.	.	H	α-helix	trans	-113	-6.9	-170.2	-59.2	-63.3	0	0	0	113.8	L79 P87	L79-Y83 PolarHBondContact O-N 3.27Å; Y83-P87 WeakPolarHBondContact O-CG 3.42Å
84	G	85.8	Confident	89.4	Confident	27 Å²	27	50.7 Å²	50.7	28%	0.278	27%	0.268	S	S	.	.			trans	86.5	167.5	-174.9	0	0	0	0	0	113.3	V80 V88	V80-G84 CarbonylContact O-C 3.38Å; V80-G84 WeakPolarHBondContact O-CA 3.23Å; V80-G84 PolarHBondContact O-N 3.12Å; G84-V88 VanDerWaalsContact O-CG2 3.3Å; G84-V88 WeakPolarHBondContact O-CG2 3.47Å
85	S	86.9	Confident	89.9	Confident	10 Å²	10	51.4 Å²	51.4	7%	0.07	27%	0.27	C	S	.	.	H	α-helix	trans	-70.5	-41.7	-176	-58.9	0	0	0	0	113.1	V80 V88 V89	V80-S85 WeakPolarHBondContact CG1-OG 3.28Å; S85-V88 PolarHBondContact O-N 3.23Å; S85-V89 WeakPolarHBondContact O-CG2 3.21Å; S85-V89 PolarHBondContact O-N 3.42Å; S85-V89 VanDerWaalsContact O-N 3.15Å
86	R	91.1	Very high	90.3	Very high	115 Å²	115	47.1 Å²	47.1	43%	0.434	25%	0.248	S	C	.	.	H	α-helix	trans	-61.2	-50.7	-173	173.2	173.9	-178.9	-169.5	4.3	113.9	V88 V89 I90 G192	R86-V88 VanDerWaalsContact C-N 3.28Å; R86-V88 PolarHBondContact O-N 3.26Å; R86-V89 PolarHBondContact O-N 2.9Å; R86-I90 HydrophobicContact CG-CD1 3.89Å; R86-I90 WeakPolarHBondContact O-CG1 3.46Å; R86-I90 PolarHBondContact O-N 3.38Å; R86-I90 VanDerWaalsContact O-N 3.13Å; R86-G192 WeakPolarHBondContact CG-O 3.36Å
87	P	92.3	Very high	90.6	Very high	71 Å²	71	48.2 Å²	48.2	46%	0.461	26%	0.256	S	S	.	.	H	α-helix	trans	-64.1	-33.5	179.4	-23.7	36.3	0	0	0	113	Y83 I90 A91	Y83-P87 WeakPolarHBondContact O-CG 3.42Å; P87-I90 PolarHBondContact O-N 3.42Å; P87-A91 WeakPolarHBondContact O-CB 3.45Å; P87-A91 PolarHBondContact O-N 3.22Å
88	V	94.1	Very high	91.2	Very high	5 Å²	5	51.3 Å²	51.3	3%	0.03	27%	0.269	C	S	.	.	H	α-helix	trans	-68.4	-43.2	-179.3	-179.4	0	0	0	0	111.2	L79 V80 G84 S85 R86 A91 G92 F126 P130	L79-V88 HydrophobicContact CB-CG2 3.9Å; V80-V88 HydrophobicContact CG2-CB 4.09Å; V80-V88 HydrophobicContact CG2-CG1 4.11Å; V80-V88 HydrophobicContact CG2-CG2 4.04Å; G84-V88 VanDerWaalsContact O-CG2 3.3Å; G84-V88 WeakPolarHBondContact O-CG2 3.47Å; S85-V88 PolarHBondContact O-N 3.23Å; R86-V88 VanDerWaalsContact C-N 3.28Å; R86-V88 PolarHBondContact O-N 3.26Å; V88-A91 PolarHBondContact O-N 3.43Å; V88-G92 PolarHBondContact O-N 3.34Å; V88-F126 HydrophobicContact CG1-CB 4Å; V88-F126 HydrophobicContact CG1-CD1 4.45Å; V88-F126 HydrophobicContact CG1-CG 4.15Å; V88-P130 HydrophobicContact CB-CG 4.08Å; V88-P130 HydrophobicContact CG1-CG 3.71Å
89	V	93.9	Very high	91.8	Very high	0 Å²	0	48 Å²	48	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-66.5	-41.2	176	-179.6	0	0	0	0	111.2	S85 R86 A91 G92 G93 N127 P130 A188 M195	S85-V89 WeakPolarHBondContact O-CG2 3.21Å; S85-V89 PolarHBondContact O-N 3.42Å; S85-V89 VanDerWaalsContact O-N 3.15Å; R86-V89 PolarHBondContact O-N 2.9Å; V89-A91 PolarHBondContact O-N 2.84Å; V89-G92 PolarHBondContact O-N 3.3Å; V89-G93 PolarHBondContact O-N 2.97Å; V89-N127 WeakPolarHBondContact CG1-OD1 3.45Å; V89-N127 PolarHBondContact O-OD1 3.49Å; V89-P130 HydrophobicContact CG2-CB 3.55Å; V89-P130 HydrophobicContact CG2-CG 3.75Å; V89-A188 WeakPolarHBondContact CG1-O 3.36Å; V89-M195 HydrophobicContact CG2-SD 3.9Å
90	I	94.9	Very high	92.3	Very high	53 Å²	53	45.5 Å²	45.5	27%	0.272	24%	0.236	S	C	.	.	H	α-helix	trans	-62.3	-45.4	176.8	-67	169.1	0	0	0	110.7	R86 P87 G92 G93 L94 C189	R86-I90 HydrophobicContact CG-CD1 3.89Å; R86-I90 WeakPolarHBondContact O-CG1 3.46Å; R86-I90 PolarHBondContact O-N 3.38Å; R86-I90 VanDerWaalsContact O-N 3.13Å; P87-I90 PolarHBondContact O-N 3.42Å; I90-G92 VanDerWaalsContact C-N 3.31Å; I90-G92 PolarHBondContact O-N 3.03Å; I90-G93 PolarHBondContact O-N 3.47Å; I90-L94 HydrophobicContact CG2-CD1 4.18Å; I90-L94 WeakPolarHBondContact O-CG 2.97Å; I90-L94 PolarHBondContact O-N 3.31Å; I90-C189 HydrophobicContact CG2-CB 4.5Å; I90-C189 PolarHBondContact O-SG 2.89Å
91	A	95.5	Very high	92.9	Very high	49 Å²	49	47.6 Å²	47.6	41%	0.405	25%	0.249	S	C	.	.	H	α-helix	trans	-62	-39	175	0	0	0	0	0	111.9	P87 V88 V89 L94 L95	P87-A91 WeakPolarHBondContact O-CB 3.45Å; P87-A91 PolarHBondContact O-N 3.22Å; V88-A91 PolarHBondContact O-N 3.43Å; V89-A91 PolarHBondContact O-N 2.84Å; A91-L94 PolarHBondContact O-N 3.45Å; A91-L95 VanDerWaalsContact O-CB 3.28Å; A91-L95 WeakPolarHBondContact O-CB 3.26Å; A91-L95 PolarHBondContact O-N 3.48Å
92	G	95.4	Very high	93.6	Very high	0 Å²	0	47.5 Å²	47.5	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-60.9	-48.8	175.4	0	0	0	0	0	113	V88 V89 I90 L95 C96 G123	V88-G92 PolarHBondContact O-N 3.34Å; V89-G92 PolarHBondContact O-N 3.3Å; I90-G92 VanDerWaalsContact C-N 3.31Å; I90-G92 PolarHBondContact O-N 3.03Å; G92-L95 PolarHBondContact O-N 3.19Å; G92-C96 PolarHBondContact O-N 3.47Å; G92-C96 PolarHBondContact O-SG 2.97Å; G92-G123 WeakPolarHBondContact O-CA 3.41Å
93	G	95.6	Very high	94.1	Very high	0 Å²	0	40.4 Å²	40.4	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-62.3	-41.3	176.1	0	0	0	0	0	113.6	V89 I90 L95 C96 C97 N127	V89-G93 PolarHBondContact O-N 2.97Å; I90-G93 PolarHBondContact O-N 3.47Å; G93-L95 VanDerWaalsContact C-N 3.34Å; G93-L95 PolarHBondContact O-N 3.16Å; G93-C96 PolarHBondContact O-N 2.95Å; G93-C97 WeakPolarHBondContact O-CB 3.37Å; G93-C97 PolarHBondContact O-N 2.71Å; G93-N127 PolarHBondContact N-OD1 2.92Å
94	L	96.7	Very high	94.5	Very high	98 Å²	98	34.1 Å²	34.1	51%	0.513	19%	0.193	S	C	.	.	H	α-helix	trans	-62.7	-41.5	173.8	-72.6	170.8	0	0	0	111.7	I90 A91 C97 L98 L186	I90-L94 HydrophobicContact CG2-CD1 4.18Å; I90-L94 WeakPolarHBondContact O-CG 2.97Å; I90-L94 PolarHBondContact O-N 3.31Å; A91-L94 PolarHBondContact O-N 3.45Å; L94-C97 PolarHBondContact O-N 3.45Å; L94-L98 WeakPolarHBondContact O-CB 3.43Å; L94-L98 PolarHBondContact O-N 2.82Å; L94-L186 HydrophobicContact CD2-CD1 3.74Å; L94-L186 HydrophobicContact CG-CD1 4.48Å
95	L	96.7	Very high	95	Very high	44 Å²	44	40 Å²	40	23%	0.23	21%	0.211	C	C	.	.	H	α-helix	trans	-66.6	-41.3	178.8	-167.5	66.3	0	0	0	111.6	A91 G92 G93 L98 G99 I119 L122	A91-L95 VanDerWaalsContact O-CB 3.28Å; A91-L95 WeakPolarHBondContact O-CB 3.26Å; A91-L95 PolarHBondContact O-N 3.48Å; G92-L95 PolarHBondContact O-N 3.19Å; G93-L95 VanDerWaalsContact C-N 3.34Å; G93-L95 PolarHBondContact O-N 3.16Å; L95-L98 PolarHBondContact O-N 3.32Å; L95-G99 PolarHBondContact O-N 3.31Å; L95-I119 HydrophobicContact CD1-CG2 3.75Å; L95-I119 HydrophobicContact CG-CG2 3.88Å; L95-I119 WeakPolarHBondContact O-CG2 3.37Å; L95-L122 HydrophobicContact CD2-CB 3.96Å; L95-L122 HydrophobicContact CD2-CD2 3.95Å; L95-L122 HydrophobicContact CD2-CG 3.92Å
96	C	96.3	Very high	95.3	Very high	0 Å²	0	39.6 Å²	39.6	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-60.7	-47.6	172.2	-71.7	0	0	0	0	112.2	G92 G93 L98 G99 M100 T120 G123 L124 L185	G92-C96 PolarHBondContact O-N 3.47Å; G92-C96 PolarHBondContact O-SG 2.97Å; G93-C96 PolarHBondContact O-N 2.95Å; C96-L98 PolarHBondContact O-N 3.17Å; C96-G99 PolarHBondContact O-N 2.93Å; C96-M100 WeakPolarHBondContact O-CG 3.32Å; C96-M100 PolarHBondContact O-N 3.32Å; C96-T120 HydrophobicContact CB-CG2 4.33Å; C96-T120 PolarHBondContact SG-O 3.08Å; C96-G123 WeakPolarHBondContact SG-CA 3.47Å; C96-L124 PolarHBondContact SG-N 3.34Å; C96-L185 HydrophobicContact CB-CB 3.93Å; C96-L185 HydrophobicContact CB-CD1 4.02Å; C96-L185 HydrophobicContact CB-CG 4.43Å
97	C	96.6	Very high	95.2	Very high	23 Å²	23	38.3 Å²	38.3	16%	0.155	22%	0.217	C	C	.	.	H	α-helix	trans	-59.5	-47.3	177.4	-177.5	0	0	0	0	111.1	G93 L94 G99 M100 V101 L186	G93-C97 WeakPolarHBondContact O-CB 3.37Å; G93-C97 PolarHBondContact O-N 2.71Å; L94-C97 PolarHBondContact O-N 3.45Å; C97-G99 PolarHBondContact O-N 2.99Å; C97-M100 PolarHBondContact O-N 2.84Å; C97-V101 WeakPolarHBondContact O-CB 3.47Å; C97-V101 VanDerWaalsContact O-CG2 3.25Å; C97-V101 WeakPolarHBondContact O-CG2 2.85Å; C97-V101 PolarHBondContact O-N 3.29Å; C97-L186 HydrophobicContact CB-CB 4.13Å; C97-L186 HydrophobicContact CB-CD1 3.88Å
98	L	96.9	Very high	95.2	Very high	93 Å²	93	36.7 Å²	36.7	49%	0.487	21%	0.208	S	C	.	.	H	α-helix	trans	-60.8	-44.5	177.7	-178.9	62.1	0	0	0	111.6	L94 L95 C96 M100 V101 L102	L94-L98 WeakPolarHBondContact O-CB 3.43Å; L94-L98 PolarHBondContact O-N 2.82Å; L95-L98 PolarHBondContact O-N 3.32Å; C96-L98 PolarHBondContact O-N 3.17Å; L98-M100 VanDerWaalsContact C-N 3.35Å; L98-M100 PolarHBondContact O-N 2.9Å; L98-V101 PolarHBondContact O-N 3.11Å; L98-L102 HydrophobicContact CD1-CD1 4.03Å; L98-L102 HydrophobicContact CD1-CG 4.07Å; L98-L102 HydrophobicContact CG-CD1 3.92Å; L98-L102 HydrophobicContact CG-CG 4.38Å; L98-L102 WeakPolarHBondContact O-CB 3.38Å; L98-L102 VanDerWaalsContact O-CG 3.24Å; L98-L102 WeakPolarHBondContact O-CG 3.33Å; L98-L102 PolarHBondContact O-N 3.34Å
99	G	96.9	Very high	95.1	Very high	0 Å²	0	37.2 Å²	37.2	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-57.7	-45.3	176.5	0	0	0	0	0	112.4	L95 C96 C97 A103 T115	L95-G99 PolarHBondContact O-N 3.31Å; C96-G99 PolarHBondContact O-N 2.93Å; C97-G99 PolarHBondContact O-N 2.99Å; G99-A103 WeakPolarHBondContact O-CB 3.45Å; G99-A103 PolarHBondContact O-N 2.74Å; G99-T115 WeakPolarHBondContact O-CB 3.33Å
100	M	96	Very high	95	Very high	0 Å²	0	42.8 Å²	42.8	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-71.2	-38.9	179	-67.1	-50.5	-59	0	0	113.7	F36 C96 C97 L98 A103 S104 V116 T120 F178 L181 L185	F36-M100 HydrophobicContact CE1-CE 4.39Å; F36-M100 HydrophobicContact CE1-SD 3.73Å; F36-M100 HydrophobicContact CZ-CE 3.74Å; F36-M100 HydrophobicContact CZ-CG 4.2Å; F36-M100 HydrophobicContact CZ-SD 3.54Å; F36-M100 VanDerWaalsContact CZ-SD 3.54Å; C96-M100 WeakPolarHBondContact O-CG 3.32Å; C96-M100 PolarHBondContact O-N 3.32Å; C97-M100 PolarHBondContact O-N 2.84Å; L98-M100 VanDerWaalsContact C-N 3.35Å; L98-M100 PolarHBondContact O-N 2.9Å; M100-A103 WeakPolarHBondContact O-CB 3.23Å; M100-A103 PolarHBondContact O-N 3.37Å; M100-S104 PolarHBondContact O-N 2.69Å; M100-S104 VanDerWaalsContact O-N 3.09Å; M100-V116 HydrophobicContact SD-CG2 4.48Å; M100-T120 HydrophobicContact CG-CG2 4.43Å; M100-T120 HydrophobicContact SD-CG2 4.18Å; M100-F178 WeakPolarHBondContact CB-O 3.44Å; M100-F178 HydrophobicContact CE-CB 3.67Å; M100-F178 HydrophobicContact CE-CD1 3.36Å; M100-F178 HydrophobicContact CE-CD2 4.29Å; M100-F178 HydrophobicContact CE-CE1 4.02Å; M100-F178 HydrophobicContact CE-CG 3.51Å; M100-L181 HydrophobicContact CE-CB 4.22Å; M100-L185 HydrophobicContact CG-CD1 3.66Å; M100-L185 HydrophobicContact SD-CD1 4.48Å
101	V	96.6	Very high	95	Very high	47 Å²	47	43.9 Å²	43.9	29%	0.285	24%	0.243	S	C	.	.	H	α-helix	trans	-63.5	-46.2	175.2	171.8	0	0	0	0	110.1	C97 L98 A103 S104 F105 L179	C97-V101 WeakPolarHBondContact O-CB 3.47Å; C97-V101 VanDerWaalsContact O-CG2 3.25Å; C97-V101 WeakPolarHBondContact O-CG2 2.85Å; C97-V101 PolarHBondContact O-N 3.29Å; L98-V101 PolarHBondContact O-N 3.11Å; V101-A103 VanDerWaalsContact C-N 3.3Å; V101-A103 PolarHBondContact O-N 3Å; V101-S104 WeakPolarHBondContact O-CB 3.49Å; V101-S104 PolarHBondContact O-N 3.45Å; V101-S104 VanDerWaalsContact O-N 3.16Å; V101-F105 HydrophobicContact CG1-CE2 4.04Å; V101-F105 WeakPolarHBondContact O-CD2 3.26Å; V101-L179 HydrophobicContact CB-CD2 4.36Å; V101-L179 HydrophobicContact CG1-CD2 4.08Å; V101-L179 HydrophobicContact CG2-CD2 4.1Å
102	L	96.2	Very high	95	Very high	76 Å²	76	41.6 Å²	41.6	40%	0.398	23%	0.225	S	C	.	.	H	α-helix	trans	-61.9	-39.2	175.3	-70.1	173.7	0	0	0	111.7	L98 S104 F105 S106 T115 I119	L98-L102 HydrophobicContact CD1-CD1 4.03Å; L98-L102 HydrophobicContact CD1-CG 4.07Å; L98-L102 HydrophobicContact CG-CD1 3.92Å; L98-L102 HydrophobicContact CG-CG 4.38Å; L98-L102 WeakPolarHBondContact O-CB 3.38Å; L98-L102 VanDerWaalsContact O-CG 3.24Å; L98-L102 WeakPolarHBondContact O-CG 3.33Å; L98-L102 PolarHBondContact O-N 3.34Å; L102-S104 VanDerWaalsContact C-N 3.25Å; L102-S104 PolarHBondContact O-N 2.96Å; L102-F105 PolarHBondContact O-N 2.97Å; L102-F105 VanDerWaalsContact O-N 3.11Å; L102-S106 PolarHBondContact O-N 3.16Å; L102-T115 HydrophobicContact CB-CG2 3.62Å; L102-I119 HydrophobicContact CD1-CD1 4.32Å
103	A	95.4	Very high	95	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-60.6	-33.4	175.8	0	0	0	0	0	112.7	G99 M100 V101 F105 S106 L112 V116 F178	G99-A103 WeakPolarHBondContact O-CB 3.45Å; G99-A103 PolarHBondContact O-N 2.74Å; M100-A103 WeakPolarHBondContact O-CB 3.23Å; M100-A103 PolarHBondContact O-N 3.37Å; V101-A103 VanDerWaalsContact C-N 3.3Å; V101-A103 PolarHBondContact O-N 3Å; A103-F105 PolarHBondContact O-N 2.89Å; A103-S106 WeakPolarHBondContact O-CB 3.11Å; A103-S106 PolarHBondContact O-N 2.68Å; A103-S106 VanDerWaalsContact O-N 3.12Å; A103-S106 PolarHBondContact O-OG 3.41Å; A103-L112 HydrophobicContact CB-CD2 4.03Å; A103-V116 HydrophobicContact CB-CG2 3.39Å; A103-F178 HydrophobicContact CB-CD2 3.85Å; A103-F178 HydrophobicContact CB-CE2 4.36Å
104	S	95.8	Very high	95	Very high	6 Å²	6	48.7 Å²	48.7	4%	0.042	26%	0.259	C	S	.	.	H	α-helix	trans	-64.5	-25.2	176.2	179.6	0	0	0	0	113.8	M100 V101 L102 K175 L179	M100-S104 PolarHBondContact O-N 2.69Å; M100-S104 VanDerWaalsContact O-N 3.09Å; V101-S104 WeakPolarHBondContact O-CB 3.49Å; V101-S104 PolarHBondContact O-N 3.45Å; V101-S104 VanDerWaalsContact O-N 3.16Å; L102-S104 VanDerWaalsContact C-N 3.25Å; L102-S104 PolarHBondContact O-N 2.96Å; S104-K175 WeakPolarHBondContact CB-O 3.44Å; S104-K175 VanDerWaalsContact O-CD 3.3Å; S104-K175 WeakPolarHBondContact O-CD 3.47Å; S104-K175 VanDerWaalsContact O-CG 3.31Å; S104-K175 WeakPolarHBondContact O-CG 3.23Å; S104-K175 PolarHBondContact OG-O 3.19Å; S104-L179 WeakPolarHBondContact OG-CG 3.25Å
105	F	94.5	Very high	95	Very high	149 Å²	149	44.7 Å²	44.7	65%	0.654	24%	0.239	S	C	*	.	T	Hydrogen-bonded Turn	trans	-95	-0.4	177.5	-63.5	-77	0	0	0	112.5	V101 L102 A103	V101-F105 HydrophobicContact CG1-CE2 4.04Å; V101-F105 WeakPolarHBondContact O-CD2 3.26Å; L102-F105 PolarHBondContact O-N 2.97Å; L102-F105 VanDerWaalsContact O-N 3.11Å; A103-F105 PolarHBondContact O-N 2.89Å
106	S	93.4	Very high	95	Very high	2 Å²	2	42.7 Å²	42.7	1%	0.014	23%	0.228	C	C	.	.			trans	-66.4	145	-178.3	65	0	0	0	0	112.3	L102 A103 E111 L112 W174	L102-S106 PolarHBondContact O-N 3.16Å; A103-S106 WeakPolarHBondContact O-CB 3.11Å; A103-S106 PolarHBondContact O-N 2.68Å; A103-S106 VanDerWaalsContact O-N 3.12Å; A103-S106 PolarHBondContact O-OG 3.41Å; S106-E111 VanDerWaalsContact CA-OE2 3.23Å; S106-E111 WeakPolarHBondContact CA-OE2 3.25Å; S106-L112 WeakPolarHBondContact OG-CD2 3.46Å; S106-L112 WeakPolarHBondContact OG-CG 3.45Å; S106-W174 WeakPolarHBondContact O-CH2 3.29Å
107	S	90.6	Very high	94.9	Very high	88 Å²	88	42.7 Å²	42.7	62%	0.615	23%	0.228	S	C	*	.			trans	-123.3	-3.3	179.5	63	0	0	0	0	112.5	F51 E111	F51-S107 VanDerWaalsContact CE1-O 3.29Å; F51-S107 WeakPolarHBondContact CE1-O 3.37Å; S107-E111 PolarHBondContact N-OE2 3.36Å; S107-E111 PolarHBondContact OG-OE2 3Å
108	S	91.6	Very high	94.9	Very high	38 Å²	38	46.8 Å²	46.8	27%	0.266	24%	0.243	S	C	.	.	S	Bend	trans	-138.7	155.7	176.2	71.1	0	0	0	0	112.1	I110 E111 L112	S108-I110 VanDerWaalsContact C-N 3.26Å; S108-I110 PolarHBondContact O-N 2.9Å; S108-E111 PolarHBondContact N-OE2 2.98Å; S108-E111 WeakPolarHBondContact O-CB 3.35Å; S108-E111 PolarHBondContact O-N 3.31Å; S108-E111 VanDerWaalsContact OG-CG 3.3Å; S108-E111 WeakPolarHBondContact OG-CG 3.31Å; S108-E111 PolarHBondContact OG-N 3.3Å; S108-L112 PolarHBondContact O-N 3.45Å
109	V	91.2	Very high	94.9	Very high	16 Å²	16	44.2 Å²	44.2	10%	0.097	23%	0.23	C	C	.	.	H	α-helix	trans	-67.6	-29.1	176.9	-178.4	0	0	0	0	111.9	F51 T53 E111 L112 Y113	F51-V109 HydrophobicContact CB-CG2 3.65Å; F51-V109 HydrophobicContact CD1-CG2 4.39Å; F51-V109 HydrophobicContact CD2-CG2 3.99Å; F51-V109 HydrophobicContact CG-CG2 3.76Å; T53-V109 HydrophobicContact CG2-CB 4.49Å; T53-V109 HydrophobicContact CG2-CG2 3.66Å; V109-E111 VanDerWaalsContact C-N 3.34Å; V109-E111 PolarHBondContact O-N 3.11Å; V109-L112 WeakPolarHBondContact O-CA 3.3Å; V109-L112 WeakPolarHBondContact O-CB 3.33Å; V109-L112 PolarHBondContact O-N 2.98Å; V109-L112 VanDerWaalsContact O-N 3.11Å; V109-Y113 HydrophobicContact CG1-CD1 4.33Å; V109-Y113 HydrophobicContact CG1-CE1 3.58Å; V109-Y113 HydrophobicContact CG1-CE2 4.33Å; V109-Y113 PolarHBondContact O-N 2.91Å
110	I	92.8	Very high	95	Very high	117 Å²	117	44.2 Å²	44.2	60%	0.6	23%	0.23	S	C	*	.	H	α-helix	trans	-64.8	-40.9	175.6	-60	173.1	0	0	0	110.7	S108 L112 Y113 L114	S108-I110 VanDerWaalsContact C-N 3.26Å; S108-I110 PolarHBondContact O-N 2.9Å; I110-L112 VanDerWaalsContact C-N 3.27Å; I110-L112 PolarHBondContact O-N 3.4Å; I110-Y113 WeakPolarHBondContact O-CB 3.46Å; I110-Y113 PolarHBondContact O-N 2.78Å; I110-L114 PolarHBondContact O-N 3.1Å
111	E	95	Very high	95	Very high	75 Å²	75	44.2 Å²	44.2	35%	0.35	23%	0.23	S	C	.	.	H	α-helix	trans	-61.5	-36.6	172.6	-73.3	167.1	-177.5	0	0	111.5	S106 S107 S108 V109 L114 T115	S106-E111 VanDerWaalsContact CA-OE2 3.23Å; S106-E111 WeakPolarHBondContact CA-OE2 3.25Å; S107-E111 PolarHBondContact N-OE2 3.36Å; S107-E111 PolarHBondContact OG-OE2 3Å; S108-E111 PolarHBondContact N-OE2 2.98Å; S108-E111 WeakPolarHBondContact O-CB 3.35Å; S108-E111 PolarHBondContact O-N 3.31Å; S108-E111 VanDerWaalsContact OG-CG 3.3Å; S108-E111 WeakPolarHBondContact OG-CG 3.31Å; S108-E111 PolarHBondContact OG-N 3.3Å; V109-E111 VanDerWaalsContact C-N 3.34Å; V109-E111 PolarHBondContact O-N 3.11Å; E111-L114 PolarHBondContact O-N 3.15Å; E111-T115 WeakPolarHBondContact O-CB 3.37Å; E111-T115 VanDerWaalsContact O-CG2 3.32Å; E111-T115 WeakPolarHBondContact O-CG2 3.26Å; E111-T115 PolarHBondContact O-N 3.1Å; E111-T115 PolarHBondContact O-OG1 3.14Å
112	L	94.8	Very high	95	Very high	2 Å²	2	43.8 Å²	43.8	1%	0.01	23%	0.226	C	C	.	.	H	α-helix	trans	-66.4	-36.3	174.4	-69.4	174.7	0	0	0	112.7	I47 F51 I61 A103 S106 S108 V109 I110 L114 T115 V116 G117 W174 F178	I47-L112 HydrophobicContact CG2-CD1 4.14Å; F51-L112 HydrophobicContact CE2-CD1 4.02Å; I61-L112 HydrophobicContact CD1-CB 4.15Å; I61-L112 HydrophobicContact CD1-CD1 4.29Å; A103-L112 HydrophobicContact CB-CD2 4.03Å; S106-L112 WeakPolarHBondContact OG-CD2 3.46Å; S106-L112 WeakPolarHBondContact OG-CG 3.45Å; S108-L112 PolarHBondContact O-N 3.45Å; V109-L112 WeakPolarHBondContact O-CA 3.3Å; V109-L112 WeakPolarHBondContact O-CB 3.33Å; V109-L112 PolarHBondContact O-N 2.98Å; V109-L112 VanDerWaalsContact O-N 3.11Å; I110-L112 VanDerWaalsContact C-N 3.27Å; I110-L112 PolarHBondContact O-N 3.4Å; L112-L114 VanDerWaalsContact C-N 3.31Å; L112-L114 PolarHBondContact O-N 3.19Å; L112-T115 WeakPolarHBondContact CA-OG1 3.41Å; L112-V116 HydrophobicContact CD2-CG2 3.92Å; L112-V116 WeakPolarHBondContact O-CB 3.42Å; L112-V116 PolarHBondContact O-N 3.35Å; L112-G117 PolarHBondContact O-N 3.28Å; L112-G117 VanDerWaalsContact O-N 3.16Å; L112-W174 HydrophobicContact CD2-CZ3 4.4Å; L112-F178 HydrophobicContact CD2-CE2 4.07Å
113	Y	95.7	Very high	95	Very high	45 Å²	45	40.2 Å²	40.2	18%	0.176	21%	0.207	C	C	.	.	I	π-helix	trans	-60.8	-41.5	172.7	-61.6	-24.2	0	0	0	111.9	E57 W60 I61 I64 V109 I110 G117 F118	E57-Y113 WeakPolarHBondContact CA-OH 3.47Å; E57-Y113 WeakPolarHBondContact CB-OH 3.44Å; E57-Y113 VanDerWaalsContact O-CE1 3.23Å; E57-Y113 WeakPolarHBondContact O-CE1 3.31Å; E57-Y113 PolarHBondContact O-OH 3.35Å; W60-Y113 HydrophobicContact CB-CD1 4.17Å; W60-Y113 HydrophobicContact CB-CE1 3.58Å; I61-Y113 HydrophobicContact CG1-CD1 3.66Å; I61-Y113 HydrophobicContact CG1-CE1 3.64Å; I64-Y113 HydrophobicContact CD1-CD1 4.17Å; I64-Y113 HydrophobicContact CD1-CG 4Å; V109-Y113 HydrophobicContact CG1-CD1 4.33Å; V109-Y113 HydrophobicContact CG1-CE1 3.58Å; V109-Y113 HydrophobicContact CG1-CE2 4.33Å; V109-Y113 PolarHBondContact O-N 2.91Å; I110-Y113 WeakPolarHBondContact O-CB 3.46Å; I110-Y113 PolarHBondContact O-N 2.78Å; Y113-G117 CarbonylContact O-C 3.56Å; Y113-G117 WeakPolarHBondContact O-CA 3.27Å; Y113-G117 PolarHBondContact O-N 3.31Å; Y113-F118 PolarHBondContact O-N 3.21Å
114	L	96.4	Very high	95	Very high	104 Å²	104	40.2 Å²	40.2	55%	0.545	21%	0.207	S	C	.	.	I	π-helix	trans	-73	-43.7	179.9	-65.5	175.9	0	0	0	111.8	I110 E111 L112 F118 I119	I110-L114 PolarHBondContact O-N 3.1Å; E111-L114 PolarHBondContact O-N 3.15Å; L112-L114 VanDerWaalsContact C-N 3.31Å; L112-L114 PolarHBondContact O-N 3.19Å; L114-F118 WeakPolarHBondContact O-CB 3.39Å; L114-F118 PolarHBondContact O-N 2.97Å; L114-I119 WeakPolarHBondContact O-CG1 3.43Å; L114-I119 PolarHBondContact O-N 2.94Å
115	T	96.6	Very high	94.9	Very high	14 Å²	14	40 Å²	40	9%	0.086	21%	0.205	C	C	.	.	I	π-helix	trans	-81.7	-61.4	-173.7	54.4	0	0	0	0	112.8	G99 L102 E111 L112 I119 T120	G99-T115 WeakPolarHBondContact O-CB 3.33Å; L102-T115 HydrophobicContact CB-CG2 3.62Å; E111-T115 WeakPolarHBondContact O-CB 3.37Å; E111-T115 VanDerWaalsContact O-CG2 3.32Å; E111-T115 WeakPolarHBondContact O-CG2 3.26Å; E111-T115 PolarHBondContact O-N 3.1Å; E111-T115 PolarHBondContact O-OG1 3.14Å; L112-T115 WeakPolarHBondContact CA-OG1 3.41Å; T115-I119 WeakPolarHBondContact O-CB 3.25Å; T115-T120 PolarHBondContact O-N 2.99Å; T115-T120 PolarHBondContact O-OG1 3.3Å
116	V	95.4	Very high	94.9	Very high	2 Å²	2	34 Å²	34	1%	0.012	18%	0.179	C	C	.	.	I	π-helix	trans	-76	-40.8	-179.6	-176.5	0	0	0	0	111	V40 I61 M65 M100 A103 L112 T120 F178	V40-V116 HydrophobicContact CG1-CG1 4.44Å; I61-V116 HydrophobicContact CG2-CB 3.92Å; I61-V116 HydrophobicContact CG2-CG1 3.73Å; M65-V116 HydrophobicContact CE-CG1 4.13Å; M65-V116 HydrophobicContact SD-CG1 4.42Å; M100-V116 HydrophobicContact SD-CG2 4.48Å; A103-V116 HydrophobicContact CB-CG2 3.39Å; L112-V116 HydrophobicContact CD2-CG2 3.92Å; L112-V116 WeakPolarHBondContact O-CB 3.42Å; L112-V116 PolarHBondContact O-N 3.35Å; V116-T120 WeakPolarHBondContact O-CB 3.37Å; V116-F178 HydrophobicContact CG2-CE2 4.36Å
117	G	95.1	Very high	95	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	18%	0.179	C	C	.	.	I	π-helix	trans	-69.6	-73.2	178.2	0	0	0	0	0	112	M65 L112 Y113 G121	M65-G117 WeakPolarHBondContact CA-O 3.22Å; L112-G117 PolarHBondContact O-N 3.28Å; L112-G117 VanDerWaalsContact O-N 3.16Å; Y113-G117 CarbonylContact O-C 3.56Å; Y113-G117 WeakPolarHBondContact O-CA 3.27Å; Y113-G117 PolarHBondContact O-N 3.31Å; G117-G121 WeakPolarHBondContact O-CA 3.44Å; G117-G121 PolarHBondContact O-N 3.22Å; G117-G121 VanDerWaalsContact O-N 3.11Å
118	F	96.8	Very high	95	Very high	108 Å²	108	30.4 Å²	30.4	47%	0.474	15%	0.153	S	C	.	.	I	π-helix	trans	-77.2	-56.4	-168.1	-176.9	-95.8	0	0	0	113.9	I64 V68 Y113 L114 G121 L122	I64-F118 HydrophobicContact CG2-CB 4.47Å; V68-F118 HydrophobicContact CG1-CD2 4.26Å; V68-F118 HydrophobicContact CG2-CD2 3.75Å; V68-F118 HydrophobicContact CG2-CE2 4.39Å; Y113-F118 PolarHBondContact O-N 3.21Å; L114-F118 WeakPolarHBondContact O-CB 3.39Å; L114-F118 PolarHBondContact O-N 2.97Å; F118-G121 PolarHBondContact O-N 3.22Å; F118-L122 WeakPolarHBondContact O-CB 3.4Å; F118-L122 PolarHBondContact O-N 2.97Å
119	I	97.3	Very high	94.8	Very high	39 Å²	39	30.8 Å²	30.8	20%	0.2	15%	0.15	C	C	.	.	I	π-helix	trans	-63.3	-51.6	-175.2	-67.9	170.9	0	0	0	110.3	L95 L102 L114 T115 L122 G123	L95-I119 HydrophobicContact CD1-CG2 3.75Å; L95-I119 HydrophobicContact CG-CG2 3.88Å; L95-I119 WeakPolarHBondContact O-CG2 3.37Å; L102-I119 HydrophobicContact CD1-CD1 4.32Å; L114-I119 WeakPolarHBondContact O-CG1 3.43Å; L114-I119 PolarHBondContact O-N 2.94Å; T115-I119 WeakPolarHBondContact O-CB 3.25Å; I119-L122 PolarHBondContact O-N 3.45Å; I119-G123 PolarHBondContact O-N 3.49Å; I119-G123 VanDerWaalsContact O-N 3.1Å
120	T	97.1	Very high	94.7	Very high	0 Å²	0	30 Å²	30	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-66.8	-41.4	-179.7	-51.3	0	0	0	0	111.1	F36 C96 M100 T115 V116 L122 G123 L124 L185	F36-T120 HydrophobicContact CD1-CG2 4.49Å; F36-T120 HydrophobicContact CE1-CG2 4.14Å; C96-T120 HydrophobicContact CB-CG2 4.33Å; C96-T120 PolarHBondContact SG-O 3.08Å; M100-T120 HydrophobicContact CG-CG2 4.43Å; M100-T120 HydrophobicContact SD-CG2 4.18Å; T115-T120 PolarHBondContact O-N 2.99Å; T115-T120 PolarHBondContact O-OG1 3.3Å; V116-T120 WeakPolarHBondContact O-CB 3.37Å; T120-L122 VanDerWaalsContact C-N 3.35Å; T120-L122 PolarHBondContact O-N 3.34Å; T120-G123 PolarHBondContact O-N 3.24Å; T120-G123 VanDerWaalsContact O-N 3.16Å; T120-L124 HydrophobicContact CG2-CG 4.48Å; T120-L124 WeakPolarHBondContact O-CG 3.37Å; T120-L124 PolarHBondContact O-N 3.12Å; T120-L185 HydrophobicContact CG2-CD1 4.21Å
121	G	96.4	Very high	94.6	Very high	0 Å²	0	24.4 Å²	24.4	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-58.6	-40.9	175.3	0	0	0	0	0	113.7	G117 F118 L124 A125	G117-G121 WeakPolarHBondContact O-CA 3.44Å; G117-G121 PolarHBondContact O-N 3.22Å; G117-G121 VanDerWaalsContact O-N 3.11Å; F118-G121 PolarHBondContact O-N 3.22Å; G121-L124 PolarHBondContact O-N 3.35Å; G121-A125 PolarHBondContact O-N 3.06Å
122	L	96.3	Very high	94.1	Very high	39 Å²	39	23.2 Å²	23.2	20%	0.204	11%	0.113	C	C	.	.	H	α-helix	trans	-66.3	-40.3	175.9	-174.3	62.8	0	0	0	111.4	V68 L95 F118 I119 T120 L124 A125 F126	V68-L122 HydrophobicContact CG1-CB 3.91Å; L95-L122 HydrophobicContact CD2-CB 3.96Å; L95-L122 HydrophobicContact CD2-CD2 3.95Å; L95-L122 HydrophobicContact CD2-CG 3.92Å; F118-L122 WeakPolarHBondContact O-CB 3.4Å; F118-L122 PolarHBondContact O-N 2.97Å; I119-L122 PolarHBondContact O-N 3.45Å; T120-L122 VanDerWaalsContact C-N 3.35Å; T120-L122 PolarHBondContact O-N 3.34Å; L122-L124 VanDerWaalsContact C-N 3.34Å; L122-L124 PolarHBondContact O-N 3.42Å; L122-A125 WeakPolarHBondContact O-CB 3.04Å; L122-A125 PolarHBondContact O-N 3.46Å; L122-F126 HydrophobicContact CD1-CE1 3.87Å; L122-F126 HydrophobicContact CD1-CE2 4.5Å; L122-F126 HydrophobicContact CD1-CZ 3.84Å; L122-F126 HydrophobicContact CD2-CZ 4.41Å; L122-F126 HydrophobicContact CG-CE1 4.38Å; L122-F126 HydrophobicContact CG-CE2 4.19Å; L122-F126 HydrophobicContact CG-CZ 4.01Å; L122-F126 WeakPolarHBondContact O-CG 3.45Å; L122-F126 PolarHBondContact O-N 3.25Å; L122-F126 VanDerWaalsContact O-N 3.09Å
123	G	96.4	Very high	93.6	Very high	0 Å²	0	24.7 Å²	24.7	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-62	-41.1	174.1	0	0	0	0	0	112.3	G92 C96 I119 T120 A125 F126 N127	G92-G123 WeakPolarHBondContact O-CA 3.41Å; C96-G123 WeakPolarHBondContact SG-CA 3.47Å; I119-G123 PolarHBondContact O-N 3.49Å; I119-G123 VanDerWaalsContact O-N 3.1Å; T120-G123 PolarHBondContact O-N 3.24Å; T120-G123 VanDerWaalsContact O-N 3.16Å; G123-A125 VanDerWaalsContact C-N 3.33Å; G123-A125 PolarHBondContact O-N 2.77Å; G123-F126 CarbonylContact O-C 3.52Å; G123-F126 PolarHBondContact O-N 3.34Å; G123-F126 VanDerWaalsContact O-N 3.14Å; G123-N127 PolarHBondContact O-N 2.89Å; G123-N127 PolarHBondContact O-ND2 2.84Å
124	L	95.7	Very high	93.1	Very high	0 Å²	0	22.6 Å²	22.6	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-64.6	-35.1	175.9	-68.3	-177.8	0	0	0	112.1	S33 F36 P37 M65 M69 C96 T120 G121 L122 F126 N127 L128 L185	S33-L124 PolarHBondContact OG-O 3.15Å; F36-L124 HydrophobicContact CB-CD1 4.4Å; F36-L124 HydrophobicContact CD1-CD1 4.35Å; P37-L124 HydrophobicContact CG-CD1 3.96Å; M65-L124 HydrophobicContact CG-CD1 4.27Å; M65-L124 HydrophobicContact SD-CD1 4.11Å; M69-L124 HydrophobicContact CG-CB 4.21Å; M69-L124 HydrophobicContact SD-CB 4.11Å; C96-L124 PolarHBondContact SG-N 3.34Å; T120-L124 HydrophobicContact CG2-CG 4.48Å; T120-L124 WeakPolarHBondContact O-CG 3.37Å; T120-L124 PolarHBondContact O-N 3.12Å; G121-L124 PolarHBondContact O-N 3.35Å; L122-L124 VanDerWaalsContact C-N 3.34Å; L122-L124 PolarHBondContact O-N 3.42Å; L124-F126 VanDerWaalsContact C-N 3.34Å; L124-N127 PolarHBondContact O-N 3.13Å; L124-L128 WeakPolarHBondContact O-CB 3.27Å; L124-L128 PolarHBondContact O-N 3.01Å; L124-L185 HydrophobicContact CD2-CD2 4.09Å
125	A	94.6	Very high	92.5	Very high	1 Å²	1	17.7 Å²	17.7	1%	0.008	9%	0.088	C	C	.	.	H	α-helix	trans	-63.9	-40	172.2	0	0	0	0	0	112.2	M69 S76 G121 L122 G123 N127 L128 Q129	M69-A125 WeakPolarHBondContact O-CB 3.31Å; S76-A125 PolarHBondContact OG-O 3.25Å; G121-A125 PolarHBondContact O-N 3.06Å; L122-A125 WeakPolarHBondContact O-CB 3.04Å; L122-A125 PolarHBondContact O-N 3.46Å; G123-A125 VanDerWaalsContact C-N 3.33Å; G123-A125 PolarHBondContact O-N 2.77Å; A125-N127 VanDerWaalsContact C-N 3.26Å; A125-N127 PolarHBondContact O-N 3.07Å; A125-L128 PolarHBondContact O-N 3.29Å; A125-Q129 PolarHBondContact O-N 3.05Å
126	F	94.6	Very high	91.7	Very high	23 Å²	23	18 Å²	18	10%	0.101	10%	0.095	C	C	.	.	H	α-helix	trans	-72.3	-18.7	177.2	-69.4	-1.3	0	0	0	112.8	I75 L79 V88 L122 G123 L124 P130	I75-F126 HydrophobicContact CG2-CE1 4.13Å; I75-F126 HydrophobicContact CG2-CZ 4.34Å; L79-F126 HydrophobicContact CD2-CE2 4.34Å; L79-F126 HydrophobicContact CD2-CZ 4.09Å; V88-F126 HydrophobicContact CG1-CB 4Å; V88-F126 HydrophobicContact CG1-CD1 4.45Å; V88-F126 HydrophobicContact CG1-CG 4.15Å; L122-F126 HydrophobicContact CD1-CE1 3.87Å; L122-F126 HydrophobicContact CD1-CE2 4.5Å; L122-F126 HydrophobicContact CD1-CZ 3.84Å; L122-F126 HydrophobicContact CD2-CZ 4.41Å; L122-F126 HydrophobicContact CG-CE1 4.38Å; L122-F126 HydrophobicContact CG-CE2 4.19Å; L122-F126 HydrophobicContact CG-CZ 4.01Å; L122-F126 WeakPolarHBondContact O-CG 3.45Å; L122-F126 PolarHBondContact O-N 3.25Å; L122-F126 VanDerWaalsContact O-N 3.09Å; G123-F126 CarbonylContact O-C 3.52Å; G123-F126 PolarHBondContact O-N 3.34Å; G123-F126 VanDerWaalsContact O-N 3.14Å; L124-F126 VanDerWaalsContact C-N 3.34Å; F126-P130 WeakPolarHBondContact O-CD 3.47Å; F126-P130 WeakPolarHBondContact O-CG 3.46Å
127	N	93.9	Very high	91.1	Very high	1 Å²	1	23.1 Å²	23.1	1%	0.005	12%	0.117	C	C	.	.	H	α-helix	trans	-84.5	-42.7	169.1	-73.7	-33.3	0	0	0	112.5	V89 G93 G123 L124 A125 A131	V89-N127 WeakPolarHBondContact CG1-OD1 3.45Å; V89-N127 PolarHBondContact O-OD1 3.49Å; G93-N127 PolarHBondContact N-OD1 2.92Å; G123-N127 PolarHBondContact O-N 2.89Å; G123-N127 PolarHBondContact O-ND2 2.84Å; L124-N127 PolarHBondContact O-N 3.13Å; A125-N127 VanDerWaalsContact C-N 3.26Å; A125-N127 PolarHBondContact O-N 3.07Å; N127-A131 WeakPolarHBondContact O-CB 3.35Å
128	L	91.1	Very high	90.5	Very high	14 Å²	14	23.5 Å²	23.5	7%	0.073	12%	0.118	C	C	.	.	H	α-helix	trans	-69.1	-54.7	-172.7	176	56.9	0	0	0	113.2	I30 Y34 M69 L124 A125 A131 L132	I30-L128 HydrophobicContact CB-CD1 4.46Å; I30-L128 HydrophobicContact CG1-CD1 3.95Å; I30-L128 HydrophobicContact CG2-CD1 4.3Å; Y34-L128 HydrophobicContact CD2-CD1 4.18Å; Y34-L128 HydrophobicContact CE2-CD1 3.56Å; Y34-L128 HydrophobicContact CE2-CD2 3.93Å; Y34-L128 HydrophobicContact CE2-CG 4.42Å; M69-L128 HydrophobicContact CE-CD2 4.44Å; M69-L128 HydrophobicContact CG-CD2 4.33Å; M69-L128 HydrophobicContact SD-CD2 4.18Å; L124-L128 WeakPolarHBondContact O-CB 3.27Å; L124-L128 PolarHBondContact O-N 3.01Å; A125-L128 PolarHBondContact O-N 3.29Å; L128-A131 WeakPolarHBondContact O-CB 3.49Å; L128-A131 PolarHBondContact O-N 3.32Å; L128-L132 HydrophobicContact CD1-CD1 4.18Å; L128-L132 HydrophobicContact CD1-CG 4.5Å; L128-L132 HydrophobicContact CG-CD1 4.5Å; L128-L132 PolarHBondContact O-N 2.93Å
129	Q	87.9	Confident	89.7	Confident	46 Å²	46	18.4 Å²	18.4	22%	0.215	10%	0.096	C	C	.	.	H	α-helix	trans	-66.8	-41.6	-170.6	-175.6	65.7	44.7	0	0	113.7	S76 A125 A131 L132 T133	S76-Q129 WeakPolarHBondContact OG-CB 3.48Å; A125-Q129 PolarHBondContact O-N 3.05Å; Q129-A131 VanDerWaalsContact C-N 3.31Å; Q129-A131 PolarHBondContact O-N 2.86Å; Q129-L132 PolarHBondContact O-N 3.49Å; Q129-T133 PolarHBondContact O-N 2.67Å; Q129-T133 VanDerWaalsContact O-N 3.09Å; Q129-T133 PolarHBondContact O-OG1 2.77Å
130	P	88.9	Confident	88.6	Confident	0 Å²	0	20.9 Å²	20.9	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-68.6	-31.5	178.4	-16	30.3	0	0	0	112.4	V80 V88 V89 F126 T133 I134	V80-P130 HydrophobicContact CG2-CB 3.6Å; V80-P130 HydrophobicContact CG2-CG 3.46Å; V80-P130 VanDerWaalsContact CG2-CG 3.46Å; V88-P130 HydrophobicContact CB-CG 4.08Å; V88-P130 HydrophobicContact CG1-CG 3.71Å; V89-P130 HydrophobicContact CG2-CB 3.55Å; V89-P130 HydrophobicContact CG2-CG 3.75Å; F126-P130 WeakPolarHBondContact O-CD 3.47Å; F126-P130 WeakPolarHBondContact O-CG 3.46Å; P130-T133 PolarHBondContact O-N 3.39Å; P130-I134 WeakPolarHBondContact O-CG2 3.35Å; P130-I134 PolarHBondContact O-N 3.37Å
131	A	89.8	Confident	87.5	Confident	0 Å²	0	29.6 Å²	29.6	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-60.2	-47	175.5	0	0	0	0	0	111.6	A26 I30 N127 L128 Q129 T133 I134 I135 M195	A26-A131 HydrophobicContact CB-CB 3.96Å; I30-A131 HydrophobicContact CD1-CB 4.41Å; I30-A131 HydrophobicContact CG1-CB 4.06Å; N127-A131 WeakPolarHBondContact O-CB 3.35Å; L128-A131 WeakPolarHBondContact O-CB 3.49Å; L128-A131 PolarHBondContact O-N 3.32Å; Q129-A131 VanDerWaalsContact C-N 3.31Å; Q129-A131 PolarHBondContact O-N 2.86Å; A131-T133 VanDerWaalsContact C-N 3.34Å; A131-T133 PolarHBondContact O-N 3.33Å; A131-I134 WeakPolarHBondContact O-CG2 3.34Å; A131-I135 WeakPolarHBondContact O-CG1 3.4Å; A131-I135 PolarHBondContact O-N 3.29Å; A131-M195 HydrophobicContact CB-CE 3.68Å
132	L	85.2	Confident	86.5	Confident	50 Å²	50	34.2 Å²	34.2	26%	0.262	16%	0.156	S	C	.	.	H	α-helix	trans	-64.3	-39.1	174.8	-68.5	173.1	0	0	0	112.3	I30 L128 Q129 G136	I30-L132 HydrophobicContact CD1-CD2 3.82Å; I30-L132 HydrophobicContact CD1-CG 4.3Å; L128-L132 HydrophobicContact CD1-CD1 4.18Å; L128-L132 HydrophobicContact CD1-CG 4.5Å; L128-L132 HydrophobicContact CG-CD1 4.5Å; L128-L132 PolarHBondContact O-N 2.93Å; Q129-L132 PolarHBondContact O-N 3.49Å; L132-G136 PolarHBondContact O-N 3.34Å
133	T	84.1	Confident	85.5	Confident	32 Å²	32	37.7 Å²	37.7	20%	0.196	17%	0.166	C	C	.	.	H	α-helix	trans	-67.8	-41.5	-178.2	-55.6	0	0	0	0	111.6	V80 Q129 P130 A131 G136 K137	V80-T133 HydrophobicContact CG1-CG2 4.13Å; Q129-T133 PolarHBondContact O-N 2.67Å; Q129-T133 VanDerWaalsContact O-N 3.09Å; Q129-T133 PolarHBondContact O-OG1 2.77Å; P130-T133 PolarHBondContact O-N 3.39Å; A131-T133 VanDerWaalsContact C-N 3.34Å; A131-T133 PolarHBondContact O-N 3.33Å; T133-G136 PolarHBondContact O-N 3.11Å; T133-K137 PolarHBondContact O-N 2.97Å
134	I	85.3	Confident	84.4	Confident	2 Å²	2	41.5 Å²	41.5	1%	0.01	19%	0.191	C	C	.	.	H	α-helix	trans	-73	-37.1	-177.3	-162.4	170.1	0	0	0	112.1	V22 P130 A131 G136 K137 Y138 M195	V22-I134 HydrophobicContact CG1-CB 4.33Å; V22-I134 HydrophobicContact CG1-CD1 4.1Å; V22-I134 HydrophobicContact CG1-CG1 4.01Å; V22-I134 HydrophobicContact CG1-CG2 3.5Å; P130-I134 WeakPolarHBondContact O-CG2 3.35Å; P130-I134 PolarHBondContact O-N 3.37Å; A131-I134 WeakPolarHBondContact O-CG2 3.34Å; I134-G136 VanDerWaalsContact C-N 3.25Å; I134-G136 PolarHBondContact O-N 3.04Å; I134-K137 WeakPolarHBondContact O-CB 3.14Å; I134-K137 PolarHBondContact O-N 3.08Å; I134-Y138 HydrophobicContact CD1-CD2 4.39Å; I134-Y138 HydrophobicContact CD1-CE2 3.87Å; I134-Y138 HydrophobicContact CG1-CD2 3.7Å; I134-Y138 HydrophobicContact CG1-CE2 3.66Å; I134-Y138 WeakPolarHBondContact O-CD2 3.49Å; I134-Y138 PolarHBondContact O-N 3.06Å; I134-M195 VanDerWaalsContact CD1-C 3.47Å; I134-M195 HydrophobicContact CD1-CB 3.45Å; I134-M195 VanDerWaalsContact CD1-CB 3.45Å; I134-M195 HydrophobicContact CD1-CG 4.09Å; I134-M195 HydrophobicContact CG2-CE 4.3Å; I134-M195 HydrophobicContact CG2-CG 4.16Å; I134-M195 HydrophobicContact CG2-SD 3.82Å
135	I	84.8	Confident	83.6	Confident	0 Å²	0	47.7 Å²	47.7	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-56.4	-45.1	172.3	-67.8	165.5	0	0	0	110.1	V23 A26 A131 K137 Y138 F139 A146 N147 A150	V23-I135 HydrophobicContact CG2-CG1 4.48Å; A26-I135 HydrophobicContact CB-CD1 3.52Å; A26-I135 HydrophobicContact CB-CG1 4Å; A131-I135 WeakPolarHBondContact O-CG1 3.4Å; A131-I135 PolarHBondContact O-N 3.29Å; I135-K137 PolarHBondContact O-N 3.36Å; I135-Y138 PolarHBondContact O-N 3.26Å; I135-F139 HydrophobicContact CG2-CD2 4.26Å; I135-F139 PolarHBondContact O-N 3.31Å; I135-A146 HydrophobicContact CG2-CB 3.63Å; I135-N147 VanDerWaalsContact CG2-OD1 3.28Å; I135-N147 WeakPolarHBondContact CG2-OD1 3.39Å; I135-A150 HydrophobicContact CD1-CB 3.5Å
136	G	78.9	Confident	83.1	Confident	22 Å²	22	47.7 Å²	47.7	23%	0.227	22%	0.222	C	C	.	.	H	α-helix	trans	-64.8	-18	177.7	0	0	0	0	0	114.9	L132 T133 I134	L132-G136 PolarHBondContact O-N 3.34Å; T133-G136 PolarHBondContact O-N 3.11Å; I134-G136 VanDerWaalsContact C-N 3.25Å; I134-G136 PolarHBondContact O-N 3.04Å
137	K	82.8	Confident	82.6	Confident	109 Å²	109	48.7 Å²	48.7	47%	0.474	23%	0.228	S	C	.	.	H	α-helix	trans	-88.9	-31.7	173.3	-70.5	179.5	178.6	178.8	0	112.7	P13 T133 I134 I135	P13-K137 VanDerWaalsContact CB-O 3.31Å; P13-K137 WeakPolarHBondContact CB-O 3.41Å; T133-K137 PolarHBondContact O-N 2.97Å; I134-K137 WeakPolarHBondContact O-CB 3.14Å; I134-K137 PolarHBondContact O-N 3.08Å; I135-K137 PolarHBondContact O-N 3.36Å
138	Y	83.6	Confident	82	Confident	7 Å²	7	50.6 Å²	50.6	3%	0.027	25%	0.248	C	C	.	.	H	α-helix	trans	-83.8	-29.1	-179.4	-89.8	-97.8	0	0	0	113.8	P14 D15 W18 V22 I134 I135 R196 L198	P14-Y138 HydrophobicContact CG-CD1 4.07Å; D15-Y138 PolarHBondContact N-O 3.3Å; W18-Y138 HydrophobicContact CB-CE1 4.31Å; V22-Y138 HydrophobicContact CG1-CD2 4.35Å; V22-Y138 HydrophobicContact CG2-CD2 4.37Å; V22-Y138 HydrophobicContact CG2-CE1 4.18Å; V22-Y138 HydrophobicContact CG2-CE2 3.98Å; I134-Y138 HydrophobicContact CD1-CD2 4.39Å; I134-Y138 HydrophobicContact CD1-CE2 3.87Å; I134-Y138 HydrophobicContact CG1-CD2 3.7Å; I134-Y138 HydrophobicContact CG1-CE2 3.66Å; I134-Y138 WeakPolarHBondContact O-CD2 3.49Å; I134-Y138 PolarHBondContact O-N 3.06Å; I135-Y138 PolarHBondContact O-N 3.26Å; Y138-R196 VanDerWaalsContact CE2-O 3.28Å; Y138-R196 WeakPolarHBondContact CE2-O 3.29Å; Y138-R196 PolarHBondContact OH-O 3.44Å; Y138-L198 HydrophobicContact CD1-CD1 3.79Å; Y138-L198 HydrophobicContact CD1-CD2 4.29Å; Y138-L198 HydrophobicContact CD1-CG 4.27Å; Y138-L198 HydrophobicContact CD2-CD1 3.6Å; Y138-L198 HydrophobicContact CD2-CG 4.04Å; Y138-L198 HydrophobicContact CE1-CD1 3.9Å; Y138-L198 HydrophobicContact CE1-CD2 3.65Å; Y138-L198 HydrophobicContact CE1-CG 3.85Å; Y138-L198 HydrophobicContact CE2-CD1 3.71Å; Y138-L198 HydrophobicContact CE2-CD2 4.27Å; Y138-L198 HydrophobicContact CE2-CG 3.58Å; Y138-L198 HydrophobicContact CG-CD1 3.66Å; Y138-L198 HydrophobicContact CG-CG 4.38Å; Y138-L198 VanDerWaalsContact CZ-CG 3.48Å
139	F	79.8	Confident	81.8	Confident	1 Å²	1	54.1 Å²	54.1	0%	0.004	27%	0.266	C	S	.	.			trans	-124.6	133.3	-176.6	-63.8	-81.9	0	0	0	111.7	D15 G19 W20 V23 I135 K142 R143 A146	D15-F139 WeakPolarHBondContact OD1-CA 3.32Å; G19-F139 VanDerWaalsContact C-CZ 3.44Å; G19-F139 WeakPolarHBondContact O-CE2 3.32Å; W20-F139 HydrophobicContact CD2-CZ 4.11Å; W20-F139 HydrophobicContact CE3-CZ 4.4Å; W20-F139 HydrophobicContact CG-CZ 4.43Å; W20-F139 HydrophobicContact CZ2-CE1 4.33Å; V23-F139 HydrophobicContact CG2-CD2 4.31Å; V23-F139 HydrophobicContact CG2-CE2 3.54Å; V23-F139 HydrophobicContact CG2-CZ 4.17Å; I135-F139 HydrophobicContact CG2-CD2 4.26Å; I135-F139 PolarHBondContact O-N 3.31Å; F139-K142 HydrophobicContact CD1-CB 3.93Å; F139-R143 HydrophobicContact CB-CB 4.16Å; F139-A146 HydrophobicContact CB-CB 4.41Å; F139-A146 HydrophobicContact CD2-CB 3.66Å; F139-A146 HydrophobicContact CE2-CB 4.01Å; F139-A146 HydrophobicContact CG-CB 3.97Å
140	Y	74	Confident	81.9	Confident	92 Å²	92	51.9 Å²	51.9	36%	0.361	26%	0.256	S	S	.	.	S	Bend	trans	-114.1	-59.3	170.6	-172.3	-103.8	0	0	0	110.4	P5 P13 D15	P5-Y140 WeakPolarHBondContact CD-OH 3.06Å; P5-Y140 VanDerWaalsContact CG-OH 3.28Å; P5-Y140 WeakPolarHBondContact CG-OH 3.33Å; P13-Y140 HydrophobicContact CG-CG 4.42Å; D15-Y140 PolarHBondContact OD1-N 3.36Å
141	R	72.9	Confident	81.8	Confident	183 Å²	183	53.9 Å²	53.9	69%	0.691	27%	0.266	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.1	-42.1	-179.8	-68.5	-177.7	171.7	175.9	-0.6	112.2	D15 R143	D15-R141 PolarHBondContact OD1-N 3.15Å; D15-R141 WeakPolarHBondContact OD2-CB 3.29Å; D15-R141 PolarHBondContact OD2-N 3.01Å; D15-R141 VanDerWaalsContact OD2-N 3.08Å; R141-R143 VanDerWaalsContact C-N 3.35Å
142	K	76.4	Confident	81.6	Confident	96 Å²	96	54.8 Å²	54.8	42%	0.417	27%	0.274	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94.1	13.5	-177.6	-61.7	178.2	-177.9	170.8	0	113.5	W20 F139 M145 A146	W20-K142 HydrophobicContact CZ2-CD 4.26Å; F139-K142 HydrophobicContact CD1-CB 3.93Å; K142-M145 PolarHBondContact O-N 3.26Å; K142-A146 PolarHBondContact O-N 3.04Å
143	R	74.6	Confident	81.8	Confident	112 Å²	112	52.4 Å²	52.4	42%	0.423	26%	0.261	S	S	.	.	H	α-helix	trans	-57.8	-42.2	-176.1	-171.2	177.9	177.4	-177.1	0.7	114.2	F139 R141 M145 A146 N147	F139-R143 HydrophobicContact CB-CB 4.16Å; R141-R143 VanDerWaalsContact C-N 3.35Å; R143-M145 VanDerWaalsContact C-N 3.34Å; R143-M145 PolarHBondContact O-N 3.31Å; R143-A146 PolarHBondContact O-N 3.39Å; R143-N147 WeakPolarHBondContact O-CB 3.36Å; R143-N147 PolarHBondContact O-N 3.22Å
144	P	73.4	Confident	82.2	Confident	81 Å²	81	51.1 Å²	51.1	53%	0.526	25%	0.253	S	S	.	.	H	α-helix	trans	-62	-40.9	177.3	-23.4	35.2	0	0	0	112.5	G148	P144-G148 PolarHBondContact O-N 3.46Å
145	M	79.8	Confident	82.5	Confident	130 Å²	130	51 Å²	51	64%	0.64	25%	0.253	S	S	*	.	H	α-helix	trans	-65.6	-44.8	176.6	-64.7	-179.1	69.8	0	0	111.6	K142 R143 G148 L149	K142-M145 PolarHBondContact O-N 3.26Å; R143-M145 VanDerWaalsContact C-N 3.34Å; R143-M145 PolarHBondContact O-N 3.31Å; M145-G148 PolarHBondContact O-N 2.91Å; M145-L149 WeakPolarHBondContact O-CB 3.4Å; M145-L149 PolarHBondContact O-N 2.85Å
146	A	82.8	Confident	82.9	Confident	0 Å²	0	52.8 Å²	52.8	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-63.2	-44	179.1	0	0	0	0	0	112.4	V23 I135 F139 K142 R143 A150	V23-A146 HydrophobicContact CG2-CB 3.76Å; I135-A146 HydrophobicContact CG2-CB 3.63Å; F139-A146 HydrophobicContact CB-CB 4.41Å; F139-A146 HydrophobicContact CD2-CB 3.66Å; F139-A146 HydrophobicContact CE2-CB 4.01Å; F139-A146 HydrophobicContact CG-CB 3.97Å; K142-A146 PolarHBondContact O-N 3.04Å; R143-A146 PolarHBondContact O-N 3.39Å; A146-A150 WeakPolarHBondContact O-CB 3.38Å; A146-A150 PolarHBondContact O-N 3.42Å
147	N	84	Confident	83.7	Confident	45 Å²	45	53.7 Å²	53.7	24%	0.241	26%	0.261	C	S	.	.	H	α-helix	trans	-63.9	-45.2	173.7	-81.7	-12.9	0	0	0	111.6	I135 R143 L149 A150 M151	I135-N147 VanDerWaalsContact CG2-OD1 3.28Å; I135-N147 WeakPolarHBondContact CG2-OD1 3.39Å; R143-N147 WeakPolarHBondContact O-CB 3.36Å; R143-N147 PolarHBondContact O-N 3.22Å; N147-L149 PolarHBondContact O-N 2.95Å; N147-A150 PolarHBondContact O-N 2.95Å; N147-M151 WeakPolarHBondContact O-CB 3.43Å; N147-M151 WeakPolarHBondContact O-CG 3.2Å; N147-M151 PolarHBondContact O-N 2.92Å
148	G	81.8	Confident	84.2	Confident	41 Å²	41	48.8 Å²	48.8	42%	0.423	24%	0.24	S	C	.	.	H	α-helix	trans	-58	-47	178.2	0	0	0	0	0	112.1	P144 M145 M151 A152	P144-G148 PolarHBondContact O-N 3.46Å; M145-G148 PolarHBondContact O-N 2.91Å; G148-M151 PolarHBondContact O-N 3.29Å; G148-A152 PolarHBondContact O-N 3.49Å
149	L	88.1	Confident	84.6	Confident	87 Å²	87	49.7 Å²	49.7	46%	0.455	25%	0.248	S	C	.	.	H	α-helix	trans	-62.1	-48	176.9	-172.2	59.4	0	0	0	111.2	W20 V23 F27 M145 N147 M151 A152	W20-L149 HydrophobicContact CZ3-CD2 4.4Å; V23-L149 HydrophobicContact CG1-CB 4.05Å; V23-L149 HydrophobicContact CG1-CD2 3.78Å; V23-L149 HydrophobicContact CG1-CG 4.02Å; F27-L149 WeakPolarHBondContact CD2-O 3.35Å; M145-L149 WeakPolarHBondContact O-CB 3.4Å; M145-L149 PolarHBondContact O-N 2.85Å; N147-L149 PolarHBondContact O-N 2.95Å; L149-M151 VanDerWaalsContact C-N 3.33Å; L149-M151 PolarHBondContact O-N 3.32Å; L149-A152 WeakPolarHBondContact O-CB 3.29Å; L149-A152 PolarHBondContact O-N 3.45Å
150	A	89	Confident	85.3	Confident	0 Å²	0	53.1 Å²	53.1	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-63.5	-37.1	179.6	0	0	0	0	0	112.9	V23 A26 I30 I135 A146 N147 G153	V23-A150 HydrophobicContact CG1-CB 4.5Å; A26-A150 HydrophobicContact CB-CB 4.05Å; I30-A150 HydrophobicContact CD1-CB 3.83Å; I135-A150 HydrophobicContact CD1-CB 3.5Å; A146-A150 WeakPolarHBondContact O-CB 3.38Å; A146-A150 PolarHBondContact O-N 3.42Å; N147-A150 PolarHBondContact O-N 2.95Å; A150-G153 PolarHBondContact O-N 3.35Å
151	M	86.6	Confident	86.3	Confident	41 Å²	41	49.1 Å²	49.1	20%	0.202	26%	0.257	C	S	.	.	H	α-helix	trans	-72	-27.7	176.7	-65.4	-128.1	77.3	0	0	113.3	I30 Y34 N147 G148 L149 G153 S154	I30-M151 HydrophobicContact CG2-CE 4.07Å; Y34-M151 HydrophobicContact CD2-CE 4.22Å; Y34-M151 HydrophobicContact CE2-CE 3.58Å; N147-M151 WeakPolarHBondContact O-CB 3.43Å; N147-M151 WeakPolarHBondContact O-CG 3.2Å; N147-M151 PolarHBondContact O-N 2.92Å; G148-M151 PolarHBondContact O-N 3.29Å; L149-M151 VanDerWaalsContact C-N 3.33Å; L149-M151 PolarHBondContact O-N 3.32Å; M151-G153 PolarHBondContact O-N 3.01Å; M151-S154 PolarHBondContact O-N 3.21Å
152	A	86.6	Confident	87.2	Confident	20 Å²	20	40.4 Å²	40.4	17%	0.165	22%	0.224	C	C	.	.	H	α-helix	trans	-64.6	-14.7	172.9	0	0	0	0	0	112.8	G148 L149 S154 P155 V156	G148-A152 PolarHBondContact O-N 3.49Å; L149-A152 WeakPolarHBondContact O-CB 3.29Å; L149-A152 PolarHBondContact O-N 3.45Å; A152-S154 VanDerWaalsContact C-N 3.26Å; A152-S154 PolarHBondContact O-N 2.88Å; A152-P155 WeakPolarHBondContact O-CD 3.48Å; A152-P155 VanDerWaalsContact O-CG 3.28Å; A152-P155 WeakPolarHBondContact O-CG 3.49Å; A152-V156 WeakPolarHBondContact O-CG2 3.32Å
153	G	89.3	Confident	88	Confident	0 Å²	0	37 Å²	37	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-62.7	-31	172	0	0	0	0	0	113.8	F27 A150 M151 V156 F157	F27-G153 VanDerWaalsContact CE2-N 3.26Å; A150-G153 PolarHBondContact O-N 3.35Å; M151-G153 PolarHBondContact O-N 3.01Å; G153-V156 PolarHBondContact O-N 2.94Å; G153-F157 WeakPolarHBondContact O-CB 3.35Å; G153-F157 VanDerWaalsContact O-CD2 3.28Å; G153-F157 WeakPolarHBondContact O-CD2 3.02Å; G153-F157 PolarHBondContact O-N 3.39Å
154	S	91.3	Very high	88.9	Confident	4 Å²	4	35.5 Å²	35.5	3%	0.028	21%	0.208	C	C	.	.	H	α-helix	trans	-58.4	-54.9	179.1	171.2	0	0	0	0	113.4	Y34 M151 A152 L158	Y34-S154 VanDerWaalsContact CB-OG 3.22Å; Y34-S154 WeakPolarHBondContact CB-OG 3.4Å; M151-S154 PolarHBondContact O-N 3.21Å; A152-S154 VanDerWaalsContact C-N 3.26Å; A152-S154 PolarHBondContact O-N 2.88Å; S154-L158 WeakPolarHBondContact O-CB 3.37Å; S154-L158 PolarHBondContact O-N 3.16Å
155	P	91.9	Very high	89.9	Confident	1 Å²	1	31.7 Å²	31.7	1%	0.006	18%	0.183	C	C	.	.	H	α-helix	trans	-66.3	-36	178.4	20.2	-30.8	0	0	0	113.2	A152 L158 S159 A290 D293 M294	A152-P155 WeakPolarHBondContact O-CD 3.48Å; A152-P155 VanDerWaalsContact O-CG 3.28Å; A152-P155 WeakPolarHBondContact O-CG 3.49Å; P155-L158 PolarHBondContact O-N 3.21Å; P155-S159 WeakPolarHBondContact O-CB 3.41Å; P155-S159 PolarHBondContact O-N 3.49Å; P155-S159 PolarHBondContact O-OG 3.3Å; P155-A290 HydrophobicContact CB-CB 4.33Å; P155-A290 WeakPolarHBondContact CB-O 3.5Å; P155-A290 WeakPolarHBondContact O-CB 3.25Å; P155-D293 HydrophobicContact CB-CB 4.48Å; P155-M294 HydrophobicContact CB-CB 3.98Å; P155-M294 HydrophobicContact CG-CB 3.98Å; P155-M294 HydrophobicContact CG-CG 4.2Å
156	V	93.4	Very high	90.5	Very high	37 Å²	37	25.5 Å²	25.5	22%	0.224	15%	0.152	C	C	.	.	H	α-helix	trans	-59.9	-51.4	176.9	174.8	0	0	0	0	110.8	F27 A152 G153 L158 S159 S160 M294	F27-V156 HydrophobicContact CE1-CG1 4.47Å; F27-V156 HydrophobicContact CZ-CB 4.02Å; F27-V156 HydrophobicContact CZ-CG1 4.24Å; F27-V156 HydrophobicContact CZ-CG2 3.98Å; A152-V156 WeakPolarHBondContact O-CG2 3.32Å; G153-V156 PolarHBondContact O-N 2.94Å; V156-L158 VanDerWaalsContact C-N 3.33Å; V156-L158 PolarHBondContact O-N 3.43Å; V156-S159 PolarHBondContact O-N 2.97Å; V156-S159 PolarHBondContact O-OG 3.28Å; V156-S160 PolarHBondContact O-N 3.06Å; V156-S160 VanDerWaalsContact O-N 3.13Å; V156-S160 PolarHBondContact O-OG 3.48Å; V156-M294 HydrophobicContact CG2-CE 3.08Å; V156-M294 HydrophobicContact CG2-CG 4.47Å; V156-M294 HydrophobicContact CG2-SD 3.55Å; V156-M294 VanDerWaalsContact CG2-SD 3.55Å
157	F	94.7	Very high	91.1	Very high	41 Å²	41	31.2 Å²	31.2	18%	0.18	18%	0.175	C	C	.	.	H	α-helix	trans	-62.7	-40.9	178.5	-87.4	-107.9	0	0	0	111.3	F27 I28 F32 A35 G153 S159 S160 L161	F27-F157 AromaticContact CD1-CE2 3.97Å; F27-F157 HydrophobicContact CD1-CE2 3.97Å; F27-F157 HydrophobicContact CE1-CD2 4.18Å; F27-F157 AromaticContact CE1-CE2 3.78Å; F27-F157 HydrophobicContact CE1-CE2 3.78Å; I28-F157 HydrophobicContact CB-CZ 4.36Å; I28-F157 HydrophobicContact CG1-CZ 4.24Å; I28-F157 HydrophobicContact CG2-CZ 4.16Å; F32-F157 AromaticContact CD1-CD1 4Å; F32-F157 HydrophobicContact CD1-CD1 4Å; F32-F157 HydrophobicContact CD1-CE1 4.14Å; F32-F157 HydrophobicContact CD2-CD1 4.22Å; F32-F157 AromaticContact CD2-CE1 3.69Å; F32-F157 HydrophobicContact CD2-CE1 3.69Å; F32-F157 HydrophobicContact CD2-CZ 4.42Å; F32-F157 AromaticContact CE1-CD1 3.99Å; F32-F157 HydrophobicContact CE1-CD1 3.99Å; F32-F157 AromaticContact CE1-CE1 3.89Å; F32-F157 HydrophobicContact CE1-CE1 3.89Å; F32-F157 HydrophobicContact CE2-CD1 4.24Å; F32-F157 AromaticContact CE2-CE1 3.42Å; F32-F157 HydrophobicContact CE2-CE1 3.42Å; F32-F157 VanDerWaalsContact CE2-CE1 3.42Å; F32-F157 HydrophobicContact CE2-CZ 4.19Å; F32-F157 HydrophobicContact CG-CD1 4.12Å; F32-F157 HydrophobicContact CG-CE1 4.05Å; F32-F157 HydrophobicContact CZ-CD1 4.13Å; F32-F157 AromaticContact CZ-CE1 3.53Å; F32-F157 HydrophobicContact CZ-CE1 3.53Å; A35-F157 HydrophobicContact CB-CB 3.67Å; G153-F157 WeakPolarHBondContact O-CB 3.35Å; G153-F157 VanDerWaalsContact O-CD2 3.28Å; G153-F157 WeakPolarHBondContact O-CD2 3.02Å; G153-F157 PolarHBondContact O-N 3.39Å; F157-S159 PolarHBondContact O-N 3.32Å; F157-S160 PolarHBondContact O-N 3.35Å; F157-L161 WeakPolarHBondContact O-CA 3.38Å; F157-L161 WeakPolarHBondContact O-CB 3.05Å; F157-L161 PolarHBondContact O-N 3.31Å
158	L	93.5	Very high	91.6	Very high	6 Å²	6	29.3 Å²	29.3	3%	0.031	17%	0.165	C	C	.	.	H	α-helix	trans	-62.9	-43.7	178	-177.7	57.3	0	0	0	112.1	A35 K38 A39 S154 P155 V156 S160 L161 A162 A290	A35-L158 HydrophobicContact CB-CB 3.88Å; K38-L158 HydrophobicContact CB-CD1 3.75Å; K38-L158 HydrophobicContact CB-CD2 4.26Å; K38-L158 HydrophobicContact CD-CD2 3.81Å; A39-L158 HydrophobicContact CB-CD1 4.08Å; S154-L158 WeakPolarHBondContact O-CB 3.37Å; S154-L158 PolarHBondContact O-N 3.16Å; P155-L158 PolarHBondContact O-N 3.21Å; V156-L158 VanDerWaalsContact C-N 3.33Å; V156-L158 PolarHBondContact O-N 3.43Å; L158-S160 VanDerWaalsContact C-N 3.29Å; L158-S160 PolarHBondContact O-N 3.22Å; L158-L161 PolarHBondContact O-N 2.93Å; L158-A162 WeakPolarHBondContact O-CB 3.41Å; L158-A162 PolarHBondContact O-N 3.4Å; L158-A162 VanDerWaalsContact O-N 3.09Å; L158-A290 HydrophobicContact CB-CB 3.93Å; L158-A290 HydrophobicContact CD2-CB 3.94Å; L158-A290 HydrophobicContact CG-CB 3.91Å
159	S	93.6	Very high	92	Very high	26 Å²	26	28.9 Å²	28.9	18%	0.182	15%	0.151	C	C	.	.	H	α-helix	trans	-64.3	-31.8	179.6	70.1	0	0	0	0	113.9	P155 V156 F157 P163 S287	P155-S159 WeakPolarHBondContact O-CB 3.41Å; P155-S159 PolarHBondContact O-N 3.49Å; P155-S159 PolarHBondContact O-OG 3.3Å; V156-S159 PolarHBondContact O-N 2.97Å; V156-S159 PolarHBondContact O-OG 3.28Å; F157-S159 PolarHBondContact O-N 3.32Å; S159-P163 VanDerWaalsContact O-CD 3.25Å; S159-P163 WeakPolarHBondContact O-CD 3.16Å; S159-P163 WeakPolarHBondContact O-CG 3.37Å; S159-S287 PolarHBondContact O-OG 3.09Å
160	S	94.1	Very high	92.2	Very high	73 Å²	73	28.3 Å²	28.3	51%	0.51	15%	0.149	S	C	.	.	H	α-helix	trans	-87.7	-39.4	178.2	-57.1	0	0	0	0	111.7	V156 F157 L158 P163 F164	V156-S160 PolarHBondContact O-N 3.06Å; V156-S160 VanDerWaalsContact O-N 3.13Å; V156-S160 PolarHBondContact O-OG 3.48Å; F157-S160 PolarHBondContact O-N 3.35Å; L158-S160 VanDerWaalsContact C-N 3.29Å; L158-S160 PolarHBondContact O-N 3.22Å; S160-P163 WeakPolarHBondContact O-CD 3.21Å; S160-P163 WeakPolarHBondContact O-CG 3.46Å; S160-F164 WeakPolarHBondContact O-CB 3.13Å; S160-F164 PolarHBondContact O-N 3.17Å
161	L	93.8	Very high	92.5	Very high	8 Å²	8	31.8 Å²	31.8	4%	0.042	17%	0.17	C	C	.	.	H	α-helix	trans	-75.5	-32.7	-172.3	-168.3	64.1	0	0	0	112.4	F36 A39 F157 L158 F164 N165 L181 L184	F36-L161 HydrophobicContact CD2-CD2 3.99Å; A39-L161 HydrophobicContact CB-CB 4.06Å; A39-L161 HydrophobicContact CB-CD2 3.63Å; A39-L161 HydrophobicContact CB-CG 3.74Å; F157-L161 WeakPolarHBondContact O-CA 3.38Å; F157-L161 WeakPolarHBondContact O-CB 3.05Å; F157-L161 PolarHBondContact O-N 3.31Å; L158-L161 PolarHBondContact O-N 2.93Å; L161-F164 HydrophobicContact CD1-CD1 4.2Å; L161-N165 WeakPolarHBondContact CD1-OD1 3.25Å; L161-N165 WeakPolarHBondContact O-CB 3.28Å; L161-N165 PolarHBondContact O-N 3.2Å; L161-N165 PolarHBondContact O-OD1 3.12Å; L161-L181 HydrophobicContact CD1-CD2 3.83Å; L161-L184 HydrophobicContact CD1-CD2 4.45Å
162	A	92.6	Very high	92.8	Very high	0 Å²	0	35.5 Å²	35.5	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-59.9	-54.6	178	0	0	0	0	0	113.5	V42 L158 N165 Q166 L286	V42-A162 HydrophobicContact CG2-CB 4.46Å; L158-A162 WeakPolarHBondContact O-CB 3.41Å; L158-A162 PolarHBondContact O-N 3.4Å; L158-A162 VanDerWaalsContact O-N 3.09Å; A162-N165 PolarHBondContact O-N 3.11Å; A162-Q166 PolarHBondContact O-N 3.33Å; A162-L286 HydrophobicContact CB-CB 4.09Å; A162-L286 HydrophobicContact CB-CD1 4.44Å
163	P	93.1	Very high	93.1	Very high	24 Å²	24	35.9 Å²	35.9	16%	0.156	19%	0.191	C	C	.	.	H	α-helix	trans	-70.6	-33.5	178.1	26.7	-34	0	0	0	111.7	S159 S160 N165 Q166 Y167 F284 S287	S159-P163 VanDerWaalsContact O-CD 3.25Å; S159-P163 WeakPolarHBondContact O-CD 3.16Å; S159-P163 WeakPolarHBondContact O-CG 3.37Å; S160-P163 WeakPolarHBondContact O-CD 3.21Å; S160-P163 WeakPolarHBondContact O-CG 3.46Å; P163-N165 VanDerWaalsContact C-N 3.33Å; P163-N165 PolarHBondContact O-N 2.63Å; P163-Q166 PolarHBondContact O-N 2.94Å; P163-Y167 PolarHBondContact O-N 2.84Å; P163-F284 HydrophobicContact CB-CE1 4.14Å; P163-F284 HydrophobicContact CB-CZ 4.29Å; P163-F284 HydrophobicContact CG-CE1 4.48Å; P163-S287 VanDerWaalsContact CD-OG 3.31Å; P163-S287 WeakPolarHBondContact CD-OG 3.33Å
164	F	94.5	Very high	93.2	Very high	81 Å²	81	36.9 Å²	36.9	36%	0.355	20%	0.195	S	C	.	.	H	α-helix	trans	-63.1	-39.3	174.6	-176.3	-112.8	0	0	0	112.2	S160 L161 Y167 L168 L184	S160-F164 WeakPolarHBondContact O-CB 3.13Å; S160-F164 PolarHBondContact O-N 3.17Å; L161-F164 HydrophobicContact CD1-CD1 4.2Å; F164-Y167 PolarHBondContact O-N 2.71Å; F164-L168 HydrophobicContact CD1-CD1 3.58Å; F164-L168 HydrophobicContact CD1-CG 4.3Å; F164-L168 HydrophobicContact CE1-CD1 3.33Å; F164-L168 HydrophobicContact CE1-CD2 4.47Å; F164-L168 HydrophobicContact CE1-CG 4.01Å; F164-L168 HydrophobicContact CE2-CG 4.43Å; F164-L168 HydrophobicContact CG-CD1 4.35Å; F164-L168 HydrophobicContact CZ-CD1 3.88Å; F164-L168 HydrophobicContact CZ-CD2 4.21Å; F164-L168 HydrophobicContact CZ-CG 4.07Å; F164-L168 WeakPolarHBondContact O-CB 3.35Å; F164-L168 WeakPolarHBondContact O-CG 3.13Å; F164-L168 PolarHBondContact O-N 3.26Å; F164-L184 HydrophobicContact CD1-CD2 4.45Å; F164-L184 HydrophobicContact CE1-CD2 3.88Å
165	N	93.9	Very high	93.3	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-63.7	-40.8	174.7	-77.4	0.4	0	0	0	111.9	A39 F43 L161 A162 P163 Y167 L168 F169 L181	A39-N165 PolarHBondContact O-ND2 3.37Å; F43-N165 HydrophobicContact CE2-CB 3.83Å; F43-N165 HydrophobicContact CZ-CB 3.7Å; L161-N165 WeakPolarHBondContact CD1-OD1 3.25Å; L161-N165 WeakPolarHBondContact O-CB 3.28Å; L161-N165 PolarHBondContact O-N 3.2Å; L161-N165 PolarHBondContact O-OD1 3.12Å; A162-N165 PolarHBondContact O-N 3.11Å; P163-N165 VanDerWaalsContact C-N 3.33Å; P163-N165 PolarHBondContact O-N 2.63Å; N165-Y167 VanDerWaalsContact C-N 3.35Å; N165-L168 PolarHBondContact O-N 3.05Å; N165-F169 WeakPolarHBondContact O-CB 3.36Å; N165-F169 PolarHBondContact O-N 3.32Å; N165-L181 WeakPolarHBondContact OD1-CD2 3.29Å
166	Q	92.3	Very high	93.4	Very high	0 Å²	0	42.2 Å²	42.2	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-64.8	-40.4	175.1	-169.3	62.9	58.1	0	0	111.5	V42 A162 P163 F169 N170 E279 Y280 A283	V42-Q166 HydrophobicContact CG1-CB 4.04Å; A162-Q166 PolarHBondContact O-N 3.33Å; P163-Q166 PolarHBondContact O-N 2.94Å; Q166-F169 WeakPolarHBondContact O-CB 3.22Å; Q166-F169 PolarHBondContact O-N 3.29Å; Q166-N170 PolarHBondContact NE2-OD1 2.93Å; Q166-N170 PolarHBondContact O-N 3.38Å; Q166-N170 PolarHBondContact O-OD1 3.11Å; Q166-E279 HydrophobicContact CG-CB 4.19Å; Q166-E279 PolarHBondContact NE2-OE2 2.97Å; Q166-Y280 HydrophobicContact CB-CD1 4.45Å; Q166-Y280 HydrophobicContact CB-CE1 4.42Å; Q166-Y280 HydrophobicContact CG-CD1 4.19Å; Q166-Y280 HydrophobicContact CG-CD2 4.41Å; Q166-Y280 HydrophobicContact CG-CE1 4.3Å; Q166-Y280 HydrophobicContact CG-CG 4.26Å; Q166-A283 HydrophobicContact CB-CB 4.09Å
167	Y	94.6	Very high	93.5	Very high	121 Å²	121	40.4 Å²	40.4	48%	0.475	21%	0.212	S	C	.	.	H	α-helix	trans	-62.2	-45.7	174.6	174.6	-98	0	0	0	112.9	P163 F164 N165 F169 N170 T171 Y280	P163-Y167 PolarHBondContact O-N 2.84Å; F164-Y167 PolarHBondContact O-N 2.71Å; N165-Y167 VanDerWaalsContact C-N 3.35Å; Y167-F169 VanDerWaalsContact C-N 3.3Å; Y167-F169 PolarHBondContact O-N 3.26Å; Y167-N170 PolarHBondContact O-N 3.46Å; Y167-T171 WeakPolarHBondContact O-CB 3.36Å; Y167-T171 PolarHBondContact O-N 3.28Å; Y167-T171 VanDerWaalsContact O-N 3.16Å; Y167-T171 PolarHBondContact O-OG1 3.42Å; Y167-Y280 WeakPolarHBondContact CA-OH 3.28Å
168	L	94.3	Very high	93.6	Very high	4 Å²	4	38.6 Å²	38.6	2%	0.021	20%	0.204	C	C	.	.	H	α-helix	trans	-59.1	-43.4	175	-77.6	166.6	0	0	0	111.3	F164 N165 T171 F172 S177 I180 L181	F164-L168 HydrophobicContact CD1-CD1 3.58Å; F164-L168 HydrophobicContact CD1-CG 4.3Å; F164-L168 HydrophobicContact CE1-CD1 3.33Å; F164-L168 HydrophobicContact CE1-CD2 4.47Å; F164-L168 HydrophobicContact CE1-CG 4.01Å; F164-L168 HydrophobicContact CE2-CG 4.43Å; F164-L168 HydrophobicContact CG-CD1 4.35Å; F164-L168 HydrophobicContact CZ-CD1 3.88Å; F164-L168 HydrophobicContact CZ-CD2 4.21Å; F164-L168 HydrophobicContact CZ-CG 4.07Å; F164-L168 WeakPolarHBondContact O-CB 3.35Å; F164-L168 WeakPolarHBondContact O-CG 3.13Å; F164-L168 PolarHBondContact O-N 3.26Å; N165-L168 PolarHBondContact O-N 3.05Å; L168-T171 PolarHBondContact O-N 3.4Å; L168-F172 HydrophobicContact CD2-CD2 4.09Å; L168-F172 HydrophobicContact CD2-CE2 4.37Å; L168-F172 PolarHBondContact O-N 2.78Å; L168-S177 WeakPolarHBondContact CB-OG 3.32Å; L168-S177 PolarHBondContact O-OG 2.77Å; L168-I180 HydrophobicContact CD1-CG2 4.32Å; L168-I180 HydrophobicContact CD2-CB 4.06Å; L168-I180 HydrophobicContact CD2-CD1 3.46Å; L168-I180 VanDerWaalsContact CD2-CD1 3.46Å; L168-I180 HydrophobicContact CD2-CG1 4.34Å; L168-I180 HydrophobicContact CD2-CG2 3.79Å; L168-L181 HydrophobicContact CD1-CD2 4.25Å; L168-L181 HydrophobicContact CD1-CG 4.37Å
169	F	91.6	Very high	93.7	Very high	32 Å²	32	41.8 Å²	41.8	14%	0.14	22%	0.221	C	C	.	.	H	α-helix	trans	-59.3	-51.4	178.4	-177	-106.8	0	0	0	111.4	F43 E46 N165 Q166 Y167 T171 G173 W174 S177	F43-F169 HydrophobicContact CD1-CB 4.01Å; F43-F169 AromaticContact CD1-CD2 3.65Å; F43-F169 HydrophobicContact CD1-CD2 3.65Å; F43-F169 HydrophobicContact CD1-CG 4.09Å; F43-F169 HydrophobicContact CE1-CB 3.68Å; F43-F169 HydrophobicContact CE1-CD2 4.01Å; F43-F169 HydrophobicContact CE1-CG 4.23Å; E46-F169 HydrophobicContact CB-CE1 4.09Å; E46-F169 HydrophobicContact CB-CE2 3.88Å; E46-F169 HydrophobicContact CB-CZ 3.4Å; E46-F169 VanDerWaalsContact CB-CZ 3.4Å; E46-F169 HydrophobicContact CG-CD1 4.48Å; E46-F169 HydrophobicContact CG-CE1 3.54Å; E46-F169 HydrophobicContact CG-CE2 4.25Å; E46-F169 HydrophobicContact CG-CZ 3.4Å; E46-F169 VanDerWaalsContact CG-CZ 3.4Å; N165-F169 WeakPolarHBondContact O-CB 3.36Å; N165-F169 PolarHBondContact O-N 3.32Å; Q166-F169 WeakPolarHBondContact O-CB 3.22Å; Q166-F169 PolarHBondContact O-N 3.29Å; Y167-F169 VanDerWaalsContact C-N 3.3Å; Y167-F169 PolarHBondContact O-N 3.26Å; F169-T171 PolarHBondContact O-N 3.4Å; F169-G173 WeakPolarHBondContact O-CA 3.49Å; F169-G173 PolarHBondContact O-N 3.47Å; F169-W174 HydrophobicContact CD2-CB 4.06Å; F169-W174 HydrophobicContact CE2-CB 3.95Å; F169-S177 WeakPolarHBondContact CA-OG 3.48Å; F169-S177 PolarHBondContact N-OG 3.38Å
170	N	91.8	Very high	93.8	Very high	76 Å²	76	42.9 Å²	42.9	41%	0.406	22%	0.224	S	C	.	.	H	α-helix	trans	-66.8	-27.3	-175.4	-69.3	17.1	0	0	0	112.5	Q166 Y167 E279 Y280	Q166-N170 PolarHBondContact NE2-OD1 2.93Å; Q166-N170 PolarHBondContact O-N 3.38Å; Q166-N170 PolarHBondContact O-OD1 3.11Å; Y167-N170 PolarHBondContact O-N 3.46Å; N170-E279 PolarHBondContact OD1-OE2 3.29Å; N170-Y280 WeakPolarHBondContact ND2-CE2 3.36Å
171	T	94.8	Very high	93.8	Very high	72 Å²	72	39.4 Å²	39.4	44%	0.442	20%	0.2	S	C	.	.	H	α-helix	trans	-92.1	-41.5	-176.3	-48.7	0	0	0	0	112.8	Y167 L168 F169	Y167-T171 WeakPolarHBondContact O-CB 3.36Å; Y167-T171 PolarHBondContact O-N 3.28Å; Y167-T171 VanDerWaalsContact O-N 3.16Å; Y167-T171 PolarHBondContact O-OG1 3.42Å; L168-T171 PolarHBondContact O-N 3.4Å; F169-T171 PolarHBondContact O-N 3.4Å
172	F	93.3	Very high	93.9	Very high	119 Å²	119	39 Å²	39	52%	0.522	20%	0.198	S	C	.	.	H	α-helix	trans	-120.8	-2.7	-169.5	-57.8	-75.3	0	0	0	113.9	L168 I180	L168-F172 HydrophobicContact CD2-CD2 4.09Å; L168-F172 HydrophobicContact CD2-CE2 4.37Å; L168-F172 PolarHBondContact O-N 2.78Å; F172-I180 HydrophobicContact CD2-CD1 3.92Å; F172-I180 HydrophobicContact CE2-CD1 4.12Å; F172-I180 HydrophobicContact CG-CD1 4.3Å
173	G	92.9	Very high	93.9	Very high	28 Å²	28	42 Å²	42	29%	0.289	22%	0.219	S	C	.	.	H	α-helix	trans	68.9	177	-170	0	0	0	0	0	112.9	F169 K175 S177	F169-G173 WeakPolarHBondContact O-CA 3.49Å; F169-G173 PolarHBondContact O-N 3.47Å; G173-K175 PolarHBondContact O-N 3.08Å; G173-S177 VanDerWaalsContact O-CB 3.3Å; G173-S177 WeakPolarHBondContact O-CB 3.4Å; G173-S177 PolarHBondContact O-N 2.95Å; G173-S177 PolarHBondContact O-OG 3.06Å
174	W	91.3	Very high	93.9	Very high	22 Å²	22	42.7 Å²	42.7	8%	0.083	22%	0.221	C	C	.	.	H	α-helix	trans	-66.7	-36.2	-176.7	66.2	-88.4	0	0	0	113.4	F43 F51 S106 L112 F169 S177 F178	F43-W174 HydrophobicContact CD1-CB 4.5Å; F51-W174 HydrophobicContact CE2-CH2 4.08Å; F51-W174 AromaticContact CE2-CZ2 3.95Å; F51-W174 HydrophobicContact CE2-CZ2 3.95Å; F51-W174 AromaticContact CZ-CH2 3.82Å; F51-W174 HydrophobicContact CZ-CH2 3.82Å; F51-W174 AromaticContact CZ-CZ2 3.74Å; F51-W174 HydrophobicContact CZ-CZ2 3.74Å; S106-W174 WeakPolarHBondContact O-CH2 3.29Å; L112-W174 HydrophobicContact CD2-CZ3 4.4Å; F169-W174 HydrophobicContact CD2-CB 4.06Å; F169-W174 HydrophobicContact CE2-CB 3.95Å; W174-S177 WeakPolarHBondContact O-CB 3.3Å; W174-S177 PolarHBondContact O-N 3.43Å; W174-F178 AromaticContact CE3-CD2 3.79Å; W174-F178 HydrophobicContact CE3-CD2 3.79Å; W174-F178 AromaticContact CE3-CE2 3.64Å; W174-F178 HydrophobicContact CE3-CE2 3.64Å; W174-F178 HydrophobicContact CE3-CZ 4.5Å; W174-F178 HydrophobicContact CZ3-CD2 4.12Å; W174-F178 HydrophobicContact CZ3-CE2 4.03Å; W174-F178 WeakPolarHBondContact O-CG 3.25Å; W174-F178 PolarHBondContact O-N 3.45Å
175	K	93.4	Very high	93.8	Very high	96 Å²	96	38.9 Å²	38.9	42%	0.417	20%	0.204	S	C	.	.	H	α-helix	trans	-63.6	-53.6	177.9	-66.3	-172.8	174.2	-175.5	0	111.4	S104 G173 S177 F178 L179	S104-K175 WeakPolarHBondContact CB-O 3.44Å; S104-K175 VanDerWaalsContact O-CD 3.3Å; S104-K175 WeakPolarHBondContact O-CD 3.47Å; S104-K175 VanDerWaalsContact O-CG 3.31Å; S104-K175 WeakPolarHBondContact O-CG 3.23Å; S104-K175 PolarHBondContact OG-O 3.19Å; G173-K175 PolarHBondContact O-N 3.08Å; K175-S177 VanDerWaalsContact C-N 3.28Å; K175-S177 PolarHBondContact O-N 2.97Å; K175-F178 PolarHBondContact O-N 3.01Å; K175-F178 VanDerWaalsContact O-N 3.16Å; K175-L179 PolarHBondContact O-N 2.81Å
176	G	94.4	Very high	93.8	Very high	20 Å²	20	41.9 Å²	41.9	21%	0.206	22%	0.22	C	C	.	.	H	α-helix	trans	-60.4	-38.1	176	0	0	0	0	0	112.6	F178 L179 I180	G176-F178 PolarHBondContact O-N 3.21Å; G176-L179 PolarHBondContact O-N 3.26Å; G176-I180 WeakPolarHBondContact O-CG1 3.48Å; G176-I180 PolarHBondContact O-N 3.2Å; G176-I180 VanDerWaalsContact O-N 3.12Å
177	S	95.6	Very high	93.7	Very high	0 Å²	0	46.1 Å²	46.1	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-59	-45.6	174.2	-60.4	0	0	0	0	112.2	L168 F169 G173 W174 K175 L179 I180 L181	L168-S177 WeakPolarHBondContact CB-OG 3.32Å; L168-S177 PolarHBondContact O-OG 2.77Å; F169-S177 WeakPolarHBondContact CA-OG 3.48Å; F169-S177 PolarHBondContact N-OG 3.38Å; G173-S177 VanDerWaalsContact O-CB 3.3Å; G173-S177 WeakPolarHBondContact O-CB 3.4Å; G173-S177 PolarHBondContact O-N 2.95Å; G173-S177 PolarHBondContact O-OG 3.06Å; W174-S177 WeakPolarHBondContact O-CB 3.3Å; W174-S177 PolarHBondContact O-N 3.43Å; K175-S177 VanDerWaalsContact C-N 3.28Å; K175-S177 PolarHBondContact O-N 2.97Å; S177-L179 PolarHBondContact O-N 2.88Å; S177-I180 PolarHBondContact O-N 3.37Å; S177-L181 WeakPolarHBondContact O-CB 3.37Å; S177-L181 VanDerWaalsContact O-CG 3.26Å; S177-L181 WeakPolarHBondContact O-CG 3.48Å; S177-L181 PolarHBondContact O-N 3.44Å
178	F	95.4	Very high	93.4	Very high	2 Å²	2	40.4 Å²	40.4	1%	0.009	22%	0.22	C	C	.	.	H	α-helix	trans	-65.2	-37.1	179.4	-72.8	-7.7	0	0	0	112.9	F43 I47 M100 A103 L112 V116 W174 K175 G176 L181 G182	F43-F178 AromaticContact CD2-CE1 3.9Å; F43-F178 HydrophobicContact CD2-CE1 3.9Å; F43-F178 HydrophobicContact CE2-CE1 4.08Å; F43-F178 HydrophobicContact CG-CE1 4.31Å; I47-F178 HydrophobicContact CD1-CE2 4.46Å; I47-F178 HydrophobicContact CD1-CZ 4.02Å; M100-F178 WeakPolarHBondContact CB-O 3.44Å; M100-F178 HydrophobicContact CE-CB 3.67Å; M100-F178 HydrophobicContact CE-CD1 3.36Å; M100-F178 HydrophobicContact CE-CD2 4.29Å; M100-F178 HydrophobicContact CE-CE1 4.02Å; M100-F178 HydrophobicContact CE-CG 3.51Å; A103-F178 HydrophobicContact CB-CD2 3.85Å; A103-F178 HydrophobicContact CB-CE2 4.36Å; L112-F178 HydrophobicContact CD2-CE2 4.07Å; V116-F178 HydrophobicContact CG2-CE2 4.36Å; W174-F178 AromaticContact CE3-CD2 3.79Å; W174-F178 HydrophobicContact CE3-CD2 3.79Å; W174-F178 AromaticContact CE3-CE2 3.64Å; W174-F178 HydrophobicContact CE3-CE2 3.64Å; W174-F178 HydrophobicContact CE3-CZ 4.5Å; W174-F178 HydrophobicContact CZ3-CD2 4.12Å; W174-F178 HydrophobicContact CZ3-CE2 4.03Å; W174-F178 WeakPolarHBondContact O-CG 3.25Å; W174-F178 PolarHBondContact O-N 3.45Å; K175-F178 PolarHBondContact O-N 3.01Å; K175-F178 VanDerWaalsContact O-N 3.16Å; G176-F178 PolarHBondContact O-N 3.21Å; F178-L181 HydrophobicContact CD1-CD1 4.3Å; F178-L181 PolarHBondContact O-N 3.4Å; F178-G182 PolarHBondContact O-N 3.23Å
179	L	95.6	Very high	93.2	Very high	73 Å²	73	41.1 Å²	41.1	38%	0.382	23%	0.226	S	C	.	.	H	α-helix	trans	-60.1	-47.6	171.9	-75.6	165.6	0	0	0	111.9	V101 S104 K175 G176 S177 G182 S183	V101-L179 HydrophobicContact CB-CD2 4.36Å; V101-L179 HydrophobicContact CG1-CD2 4.08Å; V101-L179 HydrophobicContact CG2-CD2 4.1Å; S104-L179 WeakPolarHBondContact OG-CG 3.25Å; K175-L179 PolarHBondContact O-N 2.81Å; G176-L179 PolarHBondContact O-N 3.26Å; S177-L179 PolarHBondContact O-N 2.88Å; L179-G182 PolarHBondContact O-N 3.49Å; L179-S183 PolarHBondContact O-N 2.91Å
180	I	96.3	Very high	93.2	Very high	49 Å²	49	43.7 Å²	43.7	25%	0.251	24%	0.244	S	C	.	.	H	α-helix	trans	-64.7	-44.7	179.3	-66.1	167.4	0	0	0	110.1	L168 F172 G176 S177 G182 S183 L184	L168-I180 HydrophobicContact CD1-CG2 4.32Å; L168-I180 HydrophobicContact CD2-CB 4.06Å; L168-I180 HydrophobicContact CD2-CD1 3.46Å; L168-I180 VanDerWaalsContact CD2-CD1 3.46Å; L168-I180 HydrophobicContact CD2-CG1 4.34Å; L168-I180 HydrophobicContact CD2-CG2 3.79Å; F172-I180 HydrophobicContact CD2-CD1 3.92Å; F172-I180 HydrophobicContact CE2-CD1 4.12Å; F172-I180 HydrophobicContact CG-CD1 4.3Å; G176-I180 WeakPolarHBondContact O-CG1 3.48Å; G176-I180 PolarHBondContact O-N 3.2Å; G176-I180 VanDerWaalsContact O-N 3.12Å; S177-I180 PolarHBondContact O-N 3.37Å; I180-G182 VanDerWaalsContact C-N 3.27Å; I180-G182 PolarHBondContact O-N 3.26Å; I180-S183 WeakPolarHBondContact O-CB 3.5Å; I180-S183 PolarHBondContact O-N 2.92Å; I180-S183 PolarHBondContact O-OG 2.78Å; I180-L184 HydrophobicContact CG2-CD1 3.74Å; I180-L184 WeakPolarHBondContact O-CD1 3.41Å; I180-L184 PolarHBondContact O-N 2.88Å
181	L	94.7	Very high	93	Very high	1 Å²	1	40.2 Å²	40.2	1%	0.005	23%	0.225	C	C	.	.	H	α-helix	trans	-62.1	-33.3	176.2	-72.3	176.6	0	0	0	113.1	F36 F43 M100 L161 N165 L168 S177 F178 S183 L184 L185	F36-L181 HydrophobicContact CE2-CB 4.03Å; F36-L181 HydrophobicContact CE2-CD1 4.09Å; F36-L181 HydrophobicContact CE2-CD2 4.19Å; F36-L181 HydrophobicContact CE2-CG 4.33Å; F36-L181 HydrophobicContact CZ-CB 4.32Å; F36-L181 HydrophobicContact CZ-CD1 4.32Å; F43-L181 HydrophobicContact CE2-CD1 3.89Å; F43-L181 HydrophobicContact CZ-CD1 4.08Å; M100-L181 HydrophobicContact CE-CB 4.22Å; L161-L181 HydrophobicContact CD1-CD2 3.83Å; N165-L181 WeakPolarHBondContact OD1-CD2 3.29Å; L168-L181 HydrophobicContact CD1-CD2 4.25Å; L168-L181 HydrophobicContact CD1-CG 4.37Å; S177-L181 WeakPolarHBondContact O-CB 3.37Å; S177-L181 VanDerWaalsContact O-CG 3.26Å; S177-L181 WeakPolarHBondContact O-CG 3.48Å; S177-L181 PolarHBondContact O-N 3.44Å; F178-L181 HydrophobicContact CD1-CD1 4.3Å; F178-L181 PolarHBondContact O-N 3.4Å; L181-S183 VanDerWaalsContact C-N 3.33Å; L181-S183 PolarHBondContact O-N 2.88Å; L181-L184 PolarHBondContact O-N 3.4Å; L181-L185 WeakPolarHBondContact O-CG 3.37Å; L181-L185 PolarHBondContact O-N 3.45Å
182	G	94.5	Very high	92.6	Very high	0 Å²	0	36.8 Å²	36.8	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-58.7	-43.8	170.4	0	0	0	0	0	112.2	F178 L179 I180 L185 L186	F178-G182 PolarHBondContact O-N 3.23Å; L179-G182 PolarHBondContact O-N 3.49Å; I180-G182 VanDerWaalsContact C-N 3.27Å; I180-G182 PolarHBondContact O-N 3.26Å; G182-L185 PolarHBondContact O-N 3.28Å; G182-L186 PolarHBondContact O-N 3.44Å
183	S	93.6	Very high	92.4	Very high	63 Å²	63	33.1 Å²	33.1	44%	0.441	19%	0.193	S	C	.	.	H	α-helix	trans	-66.3	-37.6	175.8	77.8	0	0	0	0	112.9	L179 I180 L181 L186 N187	L179-S183 PolarHBondContact O-N 2.91Å; I180-S183 WeakPolarHBondContact O-CB 3.5Å; I180-S183 PolarHBondContact O-N 2.92Å; I180-S183 PolarHBondContact O-OG 2.78Å; L181-S183 VanDerWaalsContact C-N 3.33Å; L181-S183 PolarHBondContact O-N 2.88Å; S183-L186 WeakPolarHBondContact O-CB 3.25Å; S183-L186 PolarHBondContact O-N 3.33Å; S183-N187 PolarHBondContact O-N 3.33Å
184	L	92.9	Very high	92.3	Very high	38 Å²	38	34.5 Å²	34.5	20%	0.199	19%	0.194	C	C	.	.	H	α-helix	trans	-64.2	-43.5	174.1	-88	77.1	0	0	0	111.2	F32 L161 F164 I180 L181 L186 N187	F32-L184 HydrophobicContact CE1-CB 4.17Å; F32-L184 HydrophobicContact CZ-CB 4.11Å; F32-L184 WeakPolarHBondContact CZ-O 3.33Å; L161-L184 HydrophobicContact CD1-CD2 4.45Å; F164-L184 HydrophobicContact CD1-CD2 4.45Å; F164-L184 HydrophobicContact CE1-CD2 3.88Å; I180-L184 HydrophobicContact CG2-CD1 3.74Å; I180-L184 WeakPolarHBondContact O-CD1 3.41Å; I180-L184 PolarHBondContact O-N 2.88Å; L181-L184 PolarHBondContact O-N 3.4Å; L184-L186 VanDerWaalsContact C-N 3.27Å; L184-L186 PolarHBondContact O-N 3.26Å; L184-N187 VanDerWaalsContact O-CB 3.29Å; L184-N187 WeakPolarHBondContact O-CB 3.05Å; L184-N187 PolarHBondContact O-N 2.83Å; L184-N187 VanDerWaalsContact O-N 3.15Å
185	L	92.6	Very high	92.1	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-66.9	-28.8	176.5	-73.6	170.3	0	0	0	112.3	F32 F36 C96 M100 T120 L124 L181 G182 N187 A188	F32-L185 HydrophobicContact CB-CD2 3.97Å; F32-L185 HydrophobicContact CD1-CD2 3.72Å; F32-L185 HydrophobicContact CE1-CD2 4.41Å; F32-L185 HydrophobicContact CG-CD2 3.98Å; F36-L185 HydrophobicContact CD1-CD1 4.37Å; F36-L185 HydrophobicContact CD2-CD1 4.07Å; F36-L185 HydrophobicContact CD2-CD2 4.05Å; F36-L185 HydrophobicContact CD2-CG 4.25Å; F36-L185 HydrophobicContact CE1-CD1 3.99Å; F36-L185 HydrophobicContact CE2-CD1 3.69Å; F36-L185 HydrophobicContact CE2-CD2 4.43Å; F36-L185 HydrophobicContact CE2-CG 4.13Å; F36-L185 HydrophobicContact CG-CD1 4.41Å; F36-L185 HydrophobicContact CG-CD2 4.31Å; F36-L185 HydrophobicContact CZ-CD1 3.65Å; C96-L185 HydrophobicContact CB-CB 3.93Å; C96-L185 HydrophobicContact CB-CD1 4.02Å; C96-L185 HydrophobicContact CB-CG 4.43Å; M100-L185 HydrophobicContact CG-CD1 3.66Å; M100-L185 HydrophobicContact SD-CD1 4.48Å; T120-L185 HydrophobicContact CG2-CD1 4.21Å; L124-L185 HydrophobicContact CD2-CD2 4.09Å; L181-L185 WeakPolarHBondContact O-CG 3.37Å; L181-L185 PolarHBondContact O-N 3.45Å; G182-L185 PolarHBondContact O-N 3.28Å; L185-N187 PolarHBondContact O-N 2.84Å; L185-A188 WeakPolarHBondContact O-CB 3.46Å; L185-A188 PolarHBondContact O-N 3.48Å
186	L	93.9	Very high	91.7	Very high	63 Å²	63	35.3 Å²	35.3	33%	0.33	19%	0.194	S	C	.	.	H	α-helix	trans	-63.9	-25.6	173.7	-167.5	67.1	0	0	0	112.3	L94 C97 G182 S183 L184 A188 C189	L94-L186 HydrophobicContact CD2-CD1 3.74Å; L94-L186 HydrophobicContact CG-CD1 4.48Å; C97-L186 HydrophobicContact CB-CB 4.13Å; C97-L186 HydrophobicContact CB-CD1 3.88Å; G182-L186 PolarHBondContact O-N 3.44Å; S183-L186 WeakPolarHBondContact O-CB 3.25Å; S183-L186 PolarHBondContact O-N 3.33Å; L184-L186 VanDerWaalsContact C-N 3.27Å; L184-L186 PolarHBondContact O-N 3.26Å; L186-A188 PolarHBondContact O-N 3.49Å; L186-A188 VanDerWaalsContact O-N 3.11Å; L186-C189 WeakPolarHBondContact O-CB 3.5Å; L186-C189 PolarHBondContact O-N 3.36Å
187	N	91.3	Very high	90.9	Very high	90 Å²	90	39.1 Å²	39.1	48%	0.481	22%	0.215	S	C	.	.	H	α-helix	trans	-61.9	-16.7	170.9	-71	-36.3	0	0	0	112.8	S183 L184 L185 C189 V190 A191	S183-N187 PolarHBondContact O-N 3.33Å; L184-N187 VanDerWaalsContact O-CB 3.29Å; L184-N187 WeakPolarHBondContact O-CB 3.05Å; L184-N187 PolarHBondContact O-N 2.83Å; L184-N187 VanDerWaalsContact O-N 3.15Å; L185-N187 PolarHBondContact O-N 2.84Å; N187-C189 PolarHBondContact O-N 3.38Å; N187-V190 WeakPolarHBondContact O-CB 3.23Å; N187-V190 PolarHBondContact O-N 2.87Å; N187-A191 PolarHBondContact O-N 3.31Å; N187-A191 VanDerWaalsContact O-N 3.08Å
188	A	86.9	Confident	89.8	Confident	0 Å²	0	43 Å²	43	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-60.5	-28.8	168.2	0	0	0	0	0	112.3	V89 L185 L186 V190 A191 G192	V89-A188 WeakPolarHBondContact CG1-O 3.36Å; L185-A188 WeakPolarHBondContact O-CB 3.46Å; L185-A188 PolarHBondContact O-N 3.48Å; L186-A188 PolarHBondContact O-N 3.49Å; L186-A188 VanDerWaalsContact O-N 3.11Å; A188-V190 VanDerWaalsContact C-N 3.34Å; A188-A191 PolarHBondContact O-N 3.35Å; A188-G192 PolarHBondContact O-N 2.99Å
189	C	90.4	Very high	88.1	Confident	20 Å²	20	45.7 Å²	45.7	14%	0.135	26%	0.264	C	S	.	.	H	α-helix	trans	-65	-38.3	172.5	-60.5	0	0	0	0	111.7	I90 L186 N187 G192 S193	I90-C189 HydrophobicContact CG2-CB 4.5Å; I90-C189 PolarHBondContact O-SG 2.89Å; L186-C189 WeakPolarHBondContact O-CB 3.5Å; L186-C189 PolarHBondContact O-N 3.36Å; N187-C189 PolarHBondContact O-N 3.38Å; C189-G192 CarbonylContact O-C 3.56Å; C189-G192 PolarHBondContact O-N 3.2Å; C189-S193 PolarHBondContact O-N 2.91Å
190	V	90.9	Very high	85.7	Confident	86 Å²	86	48.5 Å²	48.5	52%	0.521	29%	0.287	S	S	.	.	H	α-helix	trans	-64.7	-46.5	175.1	-178.3	0	0	0	0	109.7	N187 A188 G192 S193 L194	N187-V190 WeakPolarHBondContact O-CB 3.23Å; N187-V190 PolarHBondContact O-N 2.87Å; A188-V190 VanDerWaalsContact C-N 3.34Å; V190-G192 VanDerWaalsContact C-N 3.31Å; V190-G192 PolarHBondContact O-N 3.48Å; V190-S193 WeakPolarHBondContact O-CB 3.44Å; V190-S193 PolarHBondContact O-N 3Å; V190-S193 VanDerWaalsContact O-N 3.08Å; V190-S193 PolarHBondContact O-OG 3.37Å; V190-L194 PolarHBondContact O-N 3.28Å
191	A	88.1	Confident	82.9	Confident	2 Å²	2	50.1 Å²	50.1	2%	0.017	30%	0.302	C	S	.	.	H	α-helix	trans	-56.4	-44.9	172.1	0	0	0	0	0	111.6	A25 I28 N187 A188 S193 L194	A25-A191 HydrophobicContact CB-CB 4.12Å; A25-A191 VanDerWaalsContact CB-O 3.31Å; A25-A191 WeakPolarHBondContact CB-O 3.36Å; I28-A191 HydrophobicContact CB-CB 4.24Å; I28-A191 HydrophobicContact CG2-CB 4.25Å; N187-A191 PolarHBondContact O-N 3.31Å; N187-A191 VanDerWaalsContact O-N 3.08Å; A188-A191 PolarHBondContact O-N 3.35Å; A191-S193 VanDerWaalsContact C-N 3.29Å; A191-S193 PolarHBondContact O-N 3.35Å; A191-L194 WeakPolarHBondContact O-CB 3.44Å; A191-L194 PolarHBondContact O-N 3.24Å
192	G	86.6	Confident	80.4	Confident	0 Å²	0	59.2 Å²	59.2	0%	0	35%	0.345	C	S	.	.	H	α-helix	trans	-61	-32.9	175.2	0	0	0	0	0	114.1	R86 A188 C189 V190 L194 M195	R86-G192 WeakPolarHBondContact CG-O 3.36Å; A188-G192 PolarHBondContact O-N 2.99Å; C189-G192 CarbonylContact O-C 3.56Å; C189-G192 PolarHBondContact O-N 3.2Å; V190-G192 VanDerWaalsContact C-N 3.31Å; V190-G192 PolarHBondContact O-N 3.48Å; G192-L194 VanDerWaalsContact C-N 3.26Å; G192-L194 PolarHBondContact O-N 2.97Å; G192-M195 WeakPolarHBondContact O-CB 3.48Å; G192-M195 PolarHBondContact O-N 3.27Å
193	S	90	Very high	77.6	Confident	42 Å²	42	64.2 Å²	64.2	29%	0.294	38%	0.375	S	S	.	.	H	α-helix	trans	-66.2	-29.1	177.8	81.4	0	0	0	0	113.1	C189 V190 A191 M195	C189-S193 PolarHBondContact O-N 2.91Å; V190-S193 WeakPolarHBondContact O-CB 3.44Å; V190-S193 PolarHBondContact O-N 3Å; V190-S193 VanDerWaalsContact O-N 3.08Å; V190-S193 PolarHBondContact O-OG 3.37Å; A191-S193 VanDerWaalsContact C-N 3.29Å; A191-S193 PolarHBondContact O-N 3.35Å; S193-M195 VanDerWaalsContact C-N 3.3Å
194	L	90.4	Very high	74.7	Confident	57 Å²	57	66.5 Å²	66.5	30%	0.298	39%	0.387	S	S	.	.	H	α-helix	trans	-76.9	-17.7	178	-62	173	0	0	0	112.7	W18 V21 A25 V190 A191 G192 R196	W18-L194 HydrophobicContact CZ2-CD2 4.24Å; W18-L194 PolarHBondContact NE1-O 3.15Å; V21-L194 HydrophobicContact CG1-CB 4.32Å; V21-L194 HydrophobicContact CG1-CD1 4.27Å; V21-L194 HydrophobicContact CG1-CD2 4.23Å; A25-L194 HydrophobicContact CB-CB 4.01Å; A25-L194 HydrophobicContact CB-CD1 4.25Å; V190-L194 PolarHBondContact O-N 3.28Å; A191-L194 WeakPolarHBondContact O-CB 3.44Å; A191-L194 PolarHBondContact O-N 3.24Å; G192-L194 VanDerWaalsContact C-N 3.26Å; G192-L194 PolarHBondContact O-N 2.97Å; L194-R196 VanDerWaalsContact C-N 3.26Å; L194-R196 PolarHBondContact O-N 3.14Å
195	M	87.4	Confident	71.6	Confident	1 Å²	1	70 Å²	70	1%	0.005	41%	0.414	C	S	.	.			trans	-76.4	68	-179.9	-68.7	-169.3	179.9	0	0	112.3	A25 A26 V89 A131 I134 G192 S193	A25-M195 HydrophobicContact CB-CE 4.16Å; A25-M195 HydrophobicContact CB-CG 4.34Å; A26-M195 HydrophobicContact CB-CE 4.09Å; V89-M195 HydrophobicContact CG2-SD 3.9Å; A131-M195 HydrophobicContact CB-CE 3.68Å; I134-M195 VanDerWaalsContact CD1-C 3.47Å; I134-M195 HydrophobicContact CD1-CB 3.45Å; I134-M195 VanDerWaalsContact CD1-CB 3.45Å; I134-M195 HydrophobicContact CD1-CG 4.09Å; I134-M195 HydrophobicContact CG2-CE 4.3Å; I134-M195 HydrophobicContact CG2-CG 4.16Å; I134-M195 HydrophobicContact CG2-SD 3.82Å; G192-M195 WeakPolarHBondContact O-CB 3.48Å; G192-M195 PolarHBondContact O-N 3.27Å; S193-M195 VanDerWaalsContact C-N 3.3Å
196	R	84.5	Confident	68.6	Low	134 Å²	134	78.6 Å²	78.6	51%	0.506	45%	0.452	S	S	.	.			trans	-66.5	130.5	-178.6	-67.3	-177.5	-177.5	-174.7	1.6	111.4	Y138 L194 L198	Y138-R196 VanDerWaalsContact CE2-O 3.28Å; Y138-R196 WeakPolarHBondContact CE2-O 3.29Å; Y138-R196 PolarHBondContact OH-O 3.44Å; L194-R196 VanDerWaalsContact C-N 3.26Å; L194-R196 PolarHBondContact O-N 3.14Å; R196-L198 PolarHBondContact O-N 3.48Å
197	P	77.4	Confident	65.5	Low	100 Å²	100	79.6 Å²	79.6	65%	0.649	46%	0.464	S	S	*	.			trans	-67	131.8	172.7	27.7	-32.1	0	0	0	110.2	G199	P197-G199 PolarHBondContact O-N 2.85Å
198	L	72.3	Confident	62.5	Low	83 Å²	83	84.5 Å²	84.5	44%	0.435	48%	0.481	S	S	.	.			trans	-80.8	114.8	171.9	-70.9	170.1	0	0	0	109.5	P14 Y138 R196	P14-L198 HydrophobicContact CG-CD1 4.11Å; P14-L198 HydrophobicContact CG-CD2 4.24Å; Y138-L198 HydrophobicContact CD1-CD1 3.79Å; Y138-L198 HydrophobicContact CD1-CD2 4.29Å; Y138-L198 HydrophobicContact CD1-CG 4.27Å; Y138-L198 HydrophobicContact CD2-CD1 3.6Å; Y138-L198 HydrophobicContact CD2-CG 4.04Å; Y138-L198 HydrophobicContact CE1-CD1 3.9Å; Y138-L198 HydrophobicContact CE1-CD2 3.65Å; Y138-L198 HydrophobicContact CE1-CG 3.85Å; Y138-L198 HydrophobicContact CE2-CD1 3.71Å; Y138-L198 HydrophobicContact CE2-CD2 4.27Å; Y138-L198 HydrophobicContact CE2-CG 3.58Å; Y138-L198 HydrophobicContact CG-CD1 3.66Å; Y138-L198 HydrophobicContact CG-CG 4.38Å; Y138-L198 VanDerWaalsContact CZ-CG 3.48Å; R196-L198 PolarHBondContact O-N 3.48Å
199	G	59.6	Low	59.6	Low	58 Å²	58	90.6 Å²	90.6	60%	0.598	51%	0.514	S	S	*	.	S	Bend	trans	66.8	169.1	168	0	0	0	0	0	115.5	P197 S201	P197-G199 PolarHBondContact O-N 2.85Å; G199-S201 PolarHBondContact O-N 3.06Å
200	P	44.8	Very low	56.7	Low	132 Å²	132	99 Å²	99	86%	0.857	55%	0.548	S	S	*	.	S	Bend	trans	-59.8	129.1	-174.8	24.5	-30.9	0	0	0	109.4	Q202	P200-Q202 PolarHBondContact O-N 3.08Å
201	S	39	Very low	53.5	Low	82 Å²	82	100.3 Å²	100.3	57%	0.573	56%	0.556	S	S	*	*			trans	-36.5	131.8	171.8	-172.3	0	0	0	0	109.9	G199 T203	G199-S201 PolarHBondContact O-N 3.06Å; S201-T203 PolarHBondContact O-N 3.04Å; S201-T203 PolarHBondContact O-OG1 3.4Å; S201-T203 VanDerWaalsContact O-OG1 3.11Å; S201-T203 PolarHBondContact OG-N 3.13Å
202	Q	41.1	Very low	50.6	Low	193 Å²	193	106 Å²	106	90%	0.902	59%	0.591	S	S	*	*			trans	-66.9	47.7	159.7	-71.3	-170.2	0.5	0	0	110.5	P200 T204	P200-Q202 PolarHBondContact O-N 3.08Å; Q202-T204 VanDerWaalsContact C-N 3.31Å; Q202-T204 PolarHBondContact O-N 3.23Å
203	T	35.8	Very low	47.6	Very low	104 Å²	104	111.3 Å²	111.3	64%	0.638	62%	0.623	S	S	*	*			trans	-59	101.8	151.7	31.1	0	0	0	0	106.6	S201	S201-T203 PolarHBondContact O-N 3.04Å; S201-T203 PolarHBondContact O-OG1 3.4Å; S201-T203 VanDerWaalsContact O-OG1 3.11Å; S201-T203 PolarHBondContact OG-N 3.13Å
204	T	33.8	Very low	44.7	Very low	111 Å²	111	115 Å²	115	68%	0.681	64%	0.644	S	S	*	*			trans	58.2	91.2	166.9	50.7	0	0	0	0	115.6	Q202 K206	Q202-T204 VanDerWaalsContact C-N 3.31Å; Q202-T204 PolarHBondContact O-N 3.23Å; T204-K206 PolarHBondContact O-N 3Å
205	S	26.6	Very low	41.7	Very low	112 Å²	112	120.8 Å²	120.8	78%	0.783	67%	0.67	S	S	*	*				-61.3	86.9	128.5	176.9	0	0	0	0	106.4	S207	S205-S207 PolarHBondContact O-N 2.92Å; S205-S207 PolarHBondContact OG-N 3.25Å
206	K	30.1	Very low	38.9	Very low	180 Å²	180	128 Å²	128	78%	0.783	71%	0.708	S	S	*	*			trans	-58.6	96.1	139.5	-81.2	-178.2	179	177	0	103.2	T204 K208	T204-K206 PolarHBondContact O-N 3Å; K206-K208 PolarHBondContact O-N 3.27Å
207	S	28	Very low	36.6	Very low	84 Å²	84	129.5 Å²	129.5	59%	0.587	73%	0.726	S	S	*	*			trans	-47.6	104.8	151.8	-179.1	0	0	0	0	104.2	S205 N209	S205-S207 PolarHBondContact O-N 2.92Å; S205-S207 PolarHBondContact OG-N 3.25Å; S207-N209 PolarHBondContact O-N 3.02Å
208	K	28.1	Very low	34.6	Very low	193 Å²	193	129.6 Å²	129.6	84%	0.839	73%	0.729	S	S	*	*			trans	-55.9	95	154.7	-84.8	-179.7	174.3	178.8	0	102.7	K206 K210	K206-K208 PolarHBondContact O-N 3.27Å; K208-K210 PolarHBondContact O-N 3.18Å
209	N	27.8	Very low	32.7	Very low	129 Å²	129	129.9 Å²	129.9	69%	0.69	75%	0.752	S	S	*	*			trans	-52.4	96.3	151	-80.2	-0.2	0	0	0	103.6	S207 T211	S207-N209 PolarHBondContact O-N 3.02Å; N209-T211 PolarHBondContact O-N 3.44Å
210	K	28.1	Very low	31.2	Very low	195 Å²	195	135 Å²	135	85%	0.848	76%	0.761	S	S	*	*			trans	-58	99	143.9	-91.6	-175.4	171.1	-176.5	0	103.3	K208 V212	K208-K210 PolarHBondContact O-N 3.18Å; K210-V212 PolarHBondContact O-N 2.94Å
211	T	25	Very low	30.5	Very low	114 Å²	114	138.8 Å²	138.8	70%	0.699	76%	0.764	S	S	*	*			trans	-46.5	97.7	159.1	-17.3	0	0	0	0	105.5	N209 T213	N209-T211 PolarHBondContact O-N 3.44Å; T211-T213 HydrophobicContact CG2-CG2 4.12Å; T211-T213 PolarHBondContact O-N 3.37Å
212	V	26.9	Very low	30	Very low	122 Å²	122	143.9 Å²	143.9	74%	0.739	78%	0.776	S	S	*	*			trans	-76.2	96.7	148.8	178.5	0	0	0	0	102.4	K210 T214	K210-V212 PolarHBondContact O-N 2.94Å; V212-T214 PolarHBondContact O-N 3.22Å
213	T	24.2	Very low	29.7	Very low	111 Å²	111	142.2 Å²	142.2	68%	0.681	77%	0.771	S	S	*	*			trans	-63.7	93.2	161.1	37.5	0	0	0	0	106.4	T211	T211-T213 HydrophobicContact CG2-CG2 4.12Å; T211-T213 PolarHBondContact O-N 3.37Å
214	T	27.1	Very low	29.6	Very low	119 Å²	119	146.1 Å²	146.1	73%	0.73	78%	0.779	S	S	*	*			trans	-86.9	103.5	145.2	-10.8	0	0	0	0	104.5	V212 D216	V212-T214 PolarHBondContact O-N 3.22Å; T214-D216 PolarHBondContact O-N 3.18Å
215	E	28.3	Very low	29.7	Very low	179 Å²	179	146.4 Å²	146.4	84%	0.836	78%	0.783	S	S	*	*			trans	-63.9	121.1	161.8	-70.8	179.3	158.3	0	0	106.7
216	D	28.6	Very low	30.3	Very low	152 Å²	152	151 Å²	151	81%	0.813	79%	0.789	S	S	*	*			trans	-131.5	130.3	155.8	-96.9	-29.8	0	0	0	107.5	T214 S218	T214-D216 PolarHBondContact O-N 3.18Å; D216-S218 PolarHBondContact O-N 3.42Å
217	D	35.5	Very low	30.7	Very low	167 Å²	167	151.8 Å²	151.8	89%	0.893	79%	0.792	S	S	*	*			trans	-79.7	100.2	-165.2	-163.2	14.7	0	0	0	110.3
218	S	35	Very low	31.3	Very low	102 Å²	102	151.3 Å²	151.3	71%	0.713	79%	0.789	S	S	*	*			trans	-175.9	101.6	159.1	33.4	0	0	0	0	110.4	D216 Q220	D216-S218 PolarHBondContact O-N 3.42Å; S218-Q220 PolarHBondContact O-N 2.64Å
219	G	33.5	Very low	32.5	Very low	89 Å²	89	147.6 Å²	147.6	92%	0.918	78%	0.782	S	S	*	*			trans	-63.8	80.3	-176.1	0	0	0	0	0	115.6
220	Q	28.9	Very low	33	Very low	166 Å²	166	150.9 Å²	150.9	78%	0.776	79%	0.785	S	S	*	*			trans	-119.4	112.5	164.5	-74.8	-171.2	-6.2	0	0	112.2	S218 K222	S218-Q220 PolarHBondContact O-N 2.64Å; Q220-K222 PolarHBondContact O-N 3.08Å
221	K	29.3	Very low	33.8	Very low	211 Å²	211	143.8 Å²	143.8	92%	0.917	77%	0.768	S	S	*	*			trans	-63.8	97.8	169.9	-80.8	178.3	177.1	172	0	110.3	I223	K221-I223 PolarHBondContact O-N 3Å
222	K	29	Very low	35.1	Very low	189 Å²	189	145.5 Å²	145.5	82%	0.822	77%	0.766	S	S	*	*			trans	-79.4	104.4	164	-77.7	-174.4	-180	174	0	110.4	Q220 K224	Q220-K222 PolarHBondContact O-N 3.08Å; K222-K224 PolarHBondContact O-N 3.38Å
223	I	33.3	Very low	36.4	Very low	157 Å²	157	143 Å²	143	81%	0.805	75%	0.751	S	S	*	*			trans	-62.1	115.1	167.3	-61.5	170.8	0	0	0	107.9	K221	K221-I223 PolarHBondContact O-N 3Å
224	K	34	Very low	37.7	Very low	187 Å²	187	142.4 Å²	142.4	81%	0.813	74%	0.743	S	S	*	*	P	Polyproline II helix	trans	-70.5	124.7	173.6	-71.3	-177.9	-180	175.3	0	108.9	K222 K226	K222-K224 PolarHBondContact O-N 3.38Å; K224-K226 PolarHBondContact O-N 3.2Å
225	P	36.6	Very low	39.1	Very low	116 Å²	116	144.7 Å²	144.7	75%	0.753	74%	0.743	S	S	*	*	P	Polyproline II helix	trans	-67.3	136	-178.7	25.8	-31.7	0	0	0	110.6	K227	P225-K227 PolarHBondContact O-N 3.27Å; P225-K227 VanDerWaalsContact O-N 3.16Å
226	K	38.5	Very low	40.4	Very low	209 Å²	209	140.9 Å²	140.9	91%	0.909	72%	0.722	S	S	*	*	P	Polyproline II helix	trans	-54.3	118	169.7	-79.3	177.8	175.3	175	0	108.2	K224 S228	K224-K226 PolarHBondContact O-N 3.2Å; K226-S228 PolarHBondContact O-N 2.84Å
227	K	38.2	Very low	42.2	Very low	196 Å²	196	134.9 Å²	134.9	85%	0.852	69%	0.69	S	S	*	*			trans	-61.9	110.6	179.9	-71.2	-176.6	177.5	-177.8	0	109.8	P225	P225-K227 PolarHBondContact O-N 3.27Å; P225-K227 VanDerWaalsContact O-N 3.16Å
228	S	41.5	Very low	44.1	Very low	74 Å²	74	129.2 Å²	129.2	52%	0.517	66%	0.659	S	S	.	*			trans	-52.2	143.9	173.2	174.8	0	0	0	0	111.5	K226 W230 G231	K226-S228 PolarHBondContact O-N 2.84Å; S228-W230 PolarHBondContact O-N 2.79Å; S228-G231 PolarHBondContact O-N 3.34Å
229	T	52.3	Low	46.2	Very low	115 Å²	115	128.9 Å²	128.9	71%	0.706	65%	0.645	S	S	*	*	H	α-helix	trans	-49.1	-31.6	176.8	-39	0	0	0	0	112.2	G231 K232 V233	T229-G231 PolarHBondContact O-N 3.4Å; T229-K232 PolarHBondContact O-N 3.02Å; T229-V233 PolarHBondContact O-N 3.27Å
230	W	39.2	Very low	48.6	Very low	198 Å²	198	126.9 Å²	126.9	75%	0.75	62%	0.617	S	S	*	*	H	α-helix	trans	-62	-33.4	173.7	-86.5	79.7	0	0	0	114.7	S228 K232 V233 N234	S228-W230 PolarHBondContact O-N 2.79Å; W230-K232 PolarHBondContact O-N 3.23Å; W230-V233 PolarHBondContact O-N 2.82Å; W230-N234 WeakPolarHBondContact O-CB 3.18Å; W230-N234 PolarHBondContact O-N 3.37Å
231	G	44.8	Very low	51.3	Low	47 Å²	47	119.1 Å²	119.1	49%	0.485	58%	0.581	S	S	.	*	H	α-helix	trans	-69.7	-20.2	176.9	0	0	0	0	0	113.7	S228 T229	S228-G231 PolarHBondContact O-N 3.34Å; T229-G231 PolarHBondContact O-N 3.4Å
232	K	51.4	Low	54.1	Low	149 Å²	149	112.8 Å²	112.8	65%	0.648	55%	0.553	S	S	*	*	H	α-helix	trans	-81	-39.3	171.5	-71.3	178.1	-178.6	170.6	0	111.3	T229 W230 K235 Y236	T229-K232 PolarHBondContact O-N 3.02Å; W230-K232 PolarHBondContact O-N 3.23Å; K232-K235 WeakPolarHBondContact O-CB 3.32Å; K232-K235 PolarHBondContact O-N 3.45Å; K232-Y236 WeakPolarHBondContact O-CD2 3.3Å
233	V	54.9	Low	56.9	Low	70 Å²	70	112.7 Å²	112.7	42%	0.424	55%	0.553	S	S	.	*	H	α-helix	trans	-64.7	-42.5	175.1	-180	0	0	0	0	110.8	T229 W230 K235 Y236 L237	T229-V233 PolarHBondContact O-N 3.27Å; W230-V233 PolarHBondContact O-N 2.82Å; V233-K235 PolarHBondContact O-N 2.88Å; V233-K235 VanDerWaalsContact O-N 3.14Å; V233-Y236 PolarHBondContact O-N 3.26Å; V233-L237 HydrophobicContact CG1-CD1 4.12Å; V233-L237 PolarHBondContact O-N 3.32Å
234	N	52.1	Low	59.5	Low	98 Å²	98	109.1 Å²	109.1	52%	0.524	53%	0.533	S	S	.	.	H	α-helix	trans	-64.2	-16.5	176.1	-159.5	39.5	0	0	0	113.8	W230	W230-N234 WeakPolarHBondContact O-CB 3.18Å; W230-N234 PolarHBondContact O-N 3.37Å
235	K	55.9	Low	62.1	Low	168 Å²	168	106.9 Å²	106.9	73%	0.73	52%	0.519	S	S	*	.	H	α-helix	trans	-78.7	-26.1	172.2	-169.5	180	176.2	-174.1	0	112.2	K232 V233	K232-K235 WeakPolarHBondContact O-CB 3.32Å; K232-K235 PolarHBondContact O-N 3.45Å; V233-K235 PolarHBondContact O-N 2.88Å; V233-K235 VanDerWaalsContact O-N 3.14Å
236	Y	56.3	Low	64.7	Low	98 Å²	98	101.4 Å²	101.4	38%	0.384	48%	0.484	S	S	.	.	H	α-helix	trans	-100.9	-30.6	-177.5	-65.6	-70.1	0	0	0	112.8	V78 K232 V233 S373	V78-Y236 HydrophobicContact CG2-CD2 4.28Å; V78-Y236 HydrophobicContact CG2-CE2 4.35Å; K232-Y236 WeakPolarHBondContact O-CD2 3.3Å; V233-Y236 PolarHBondContact O-N 3.26Å; Y236-S373 PolarHBondContact O-OG 3.4Å
237	L	66.9	Low	67.3	Low	27 Å²	27	91.4 Å²	91.4	14%	0.141	44%	0.44	C	S	.	.	S	Bend	trans	-112.4	95.5	174.6	-62.7	176.2	0	0	0	108.8	V233 F239 L377	V233-L237 HydrophobicContact CG1-CD1 4.12Å; V233-L237 PolarHBondContact O-N 3.32Å; L237-F239 HydrophobicContact CB-CD2 4.39Å; L237-F239 HydrophobicContact CB-CE2 3.85Å; L237-F239 HydrophobicContact CB-CZ 4.23Å; L237-F239 HydrophobicContact CD1-CZ 4.47Å; L237-F239 WeakPolarHBondContact O-CD2 3.48Å; L237-F239 PolarHBondContact O-N 2.9Å; L237-L377 HydrophobicContact CB-CD1 3.69Å; L237-L377 HydrophobicContact CD2-CD1 3.73Å; L237-L377 HydrophobicContact CG-CD1 4.15Å
238	D	73.8	Confident	69.9	Low	47 Å²	47	85.7 Å²	85.7	25%	0.251	42%	0.419	S	S	.	.			trans	-77.2	87.2	178.3	-175.7	2.1	0	0	0	109.4	S240 L241 S373	D238-S240 PolarHBondContact O-N 3.36Å; D238-S240 WeakPolarHBondContact OD1-CB 3.38Å; D238-S240 PolarHBondContact OD1-N 2.92Å; D238-S240 VanDerWaalsContact OD1-N 3.08Å; D238-S240 PolarHBondContact OD1-OG 2.83Å; D238-S240 PolarHBondContact OD2-OG 3.46Å; D238-S240 VanDerWaalsContact OD2-OG 3.14Å; D238-L241 HydrophobicContact CB-CD1 4.39Å; D238-L241 WeakPolarHBondContact O-CB 3.21Å; D238-L241 WeakPolarHBondContact O-CG 3.26Å; D238-L241 PolarHBondContact O-N 3.38Å; D238-S373 WeakPolarHBondContact CB-OG 3.32Å; D238-S373 PolarHBondContact N-OG 2.96Å
239	F	80.1	Confident	72.4	Confident	96 Å²	96	83.6 Å²	83.6	42%	0.421	40%	0.401	S	S	.	.	G	3₁₀ helix	trans	-60.7	-10.3	177.4	-69.8	-85.9	0	0	0	113.3	L237 L241 F242 L377	L237-F239 HydrophobicContact CB-CD2 4.39Å; L237-F239 HydrophobicContact CB-CE2 3.85Å; L237-F239 HydrophobicContact CB-CZ 4.23Å; L237-F239 HydrophobicContact CD1-CZ 4.47Å; L237-F239 WeakPolarHBondContact O-CD2 3.48Å; L237-F239 PolarHBondContact O-N 2.9Å; F239-L241 PolarHBondContact O-N 3.41Å; F239-F242 HydrophobicContact CB-CD2 4.35Å; F239-F242 AromaticContact CD1-CD2 3.82Å; F239-F242 HydrophobicContact CD1-CD2 3.82Å; F239-F242 AromaticContact CD1-CE2 3.6Å; F239-F242 HydrophobicContact CD1-CE2 3.6Å; F239-F242 HydrophobicContact CE1-CE2 4.08Å; F239-F242 WeakPolarHBondContact O-CB 3.12Å; F239-F242 PolarHBondContact O-N 3.48Å; F239-F242 VanDerWaalsContact O-N 3.13Å; F239-L377 HydrophobicContact CE1-CD1 4.39Å
240	S	83.8	Confident	74.5	Confident	47 Å²	47	78.2 Å²	78.2	33%	0.329	37%	0.368	S	S	.	.	G	3₁₀ helix	trans	-63.5	-20.3	171.7	81.1	0	0	0	0	112.8	D238 F242 K243	D238-S240 PolarHBondContact O-N 3.36Å; D238-S240 WeakPolarHBondContact OD1-CB 3.38Å; D238-S240 PolarHBondContact OD1-N 2.92Å; D238-S240 VanDerWaalsContact OD1-N 3.08Å; D238-S240 PolarHBondContact OD1-OG 2.83Å; D238-S240 PolarHBondContact OD2-OG 3.46Å; D238-S240 VanDerWaalsContact OD2-OG 3.14Å; S240-F242 PolarHBondContact O-N 3.41Å; S240-K243 WeakPolarHBondContact O-CB 3.33Å; S240-K243 PolarHBondContact O-N 3.5Å
241	L	85.1	Confident	77.1	Confident	3 Å²	3	69.5 Å²	69.5	2%	0.016	34%	0.336	C	S	.	.	G	3₁₀ helix	trans	-60.6	-27.3	173.3	-73.6	165	0	0	0	112.7	D238 F239 K243 H244 F247 V366 R370 A374 L377	D238-L241 HydrophobicContact CB-CD1 4.39Å; D238-L241 WeakPolarHBondContact O-CB 3.21Å; D238-L241 WeakPolarHBondContact O-CG 3.26Å; D238-L241 PolarHBondContact O-N 3.38Å; F239-L241 PolarHBondContact O-N 3.41Å; L241-K243 PolarHBondContact O-N 2.95Å; L241-K243 VanDerWaalsContact O-N 3.08Å; L241-H244 WeakPolarHBondContact O-CB 3.46Å; L241-H244 PolarHBondContact O-N 2.89Å; L241-F247 HydrophobicContact CB-CD1 4.01Å; L241-F247 HydrophobicContact CB-CE1 4Å; L241-F247 HydrophobicContact CB-CG 4.47Å; L241-F247 HydrophobicContact CB-CZ 4.44Å; L241-F247 VanDerWaalsContact O-CD1 3.28Å; L241-F247 WeakPolarHBondContact O-CD1 3.43Å; L241-V366 HydrophobicContact CD2-CG1 3.61Å; L241-V366 HydrophobicContact CD2-CG2 4.17Å; L241-R370 HydrophobicContact CD2-CB 4.39Å; L241-A374 HydrophobicContact CD1-CB 3.74Å; L241-L377 HydrophobicContact CB-CD2 4.19Å; L241-L377 HydrophobicContact CD1-CD2 4.46Å
242	F	88.9	Confident	79.6	Confident	78 Å²	78	69.2 Å²	69.2	34%	0.342	33%	0.327	S	S	.	.	G	3₁₀ helix	trans	-69.7	0.1	173.6	-70.1	-69	0	0	0	114.1	F239 S240 F247 L248 L251 L377	F239-F242 HydrophobicContact CB-CD2 4.35Å; F239-F242 AromaticContact CD1-CD2 3.82Å; F239-F242 HydrophobicContact CD1-CD2 3.82Å; F239-F242 AromaticContact CD1-CE2 3.6Å; F239-F242 HydrophobicContact CD1-CE2 3.6Å; F239-F242 HydrophobicContact CE1-CE2 4.08Å; F239-F242 WeakPolarHBondContact O-CB 3.12Å; F239-F242 PolarHBondContact O-N 3.48Å; F239-F242 VanDerWaalsContact O-N 3.13Å; S240-F242 PolarHBondContact O-N 3.41Å; F242-F247 HydrophobicContact CD1-CE1 4.37Å; F242-F247 HydrophobicContact CE1-CE1 4.38Å; F242-L248 VanDerWaalsContact C-CD1 3.45Å; F242-L248 WeakPolarHBondContact O-CD1 3.37Å; F242-L251 HydrophobicContact CD1-CD2 4.36Å; F242-L251 HydrophobicContact CE1-CD2 3.54Å; F242-L251 HydrophobicContact CZ-CD2 4.35Å; F242-L377 HydrophobicContact CD2-CD2 3.86Å; F242-L377 HydrophobicContact CE1-CD2 4.36Å; F242-L377 HydrophobicContact CE2-CD1 4.26Å; F242-L377 HydrophobicContact CE2-CD2 3.33Å; F242-L377 HydrophobicContact CE2-CG 3.84Å; F242-L377 HydrophobicContact CZ-CD2 3.62Å; F242-L377 HydrophobicContact CZ-CG 3.93Å
243	K	86.3	Confident	81.7	Confident	187 Å²	187	62.1 Å²	62.1	81%	0.813	30%	0.296	S	S	*	.	G	3₁₀ helix	trans	-97	-10.6	168.7	-61.4	-177.4	177.5	-177	0	112.6	S240 L241 R245	S240-K243 WeakPolarHBondContact O-CB 3.33Å; S240-K243 PolarHBondContact O-N 3.5Å; L241-K243 PolarHBondContact O-N 2.95Å; L241-K243 VanDerWaalsContact O-N 3.08Å; K243-R245 PolarHBondContact O-N 3.48Å
244	H	88.4	Confident	83.6	Confident	82 Å²	82	58.8 Å²	58.8	38%	0.38	28%	0.275	S	S	.	.			trans	-85.8	112.2	-176.4	-171.5	-96.5	0	0	0	111	L241 G246 F247 L248 L365	L241-H244 WeakPolarHBondContact O-CB 3.46Å; L241-H244 PolarHBondContact O-N 2.89Å; H244-G246 PolarHBondContact O-N 3.45Å; H244-F247 HydrophobicContact CB-CB 3.96Å; H244-F247 PolarHBondContact ND1-N 2.92Å; H244-F247 WeakPolarHBondContact O-CB 3.41Å; H244-F247 PolarHBondContact O-N 3.47Å; H244-L248 VanDerWaalsContact O-CD1 3.22Å; H244-L248 WeakPolarHBondContact O-CD1 3.3Å; H244-L248 PolarHBondContact O-N 3.08Å; H244-L248 VanDerWaalsContact O-N 3.1Å; H244-L365 PolarHBondContact CE1-O 3.28Å; H244-L365 VanDerWaalsContact CE1-O 3.24Å
245	R	89.9	Confident	85.7	Confident	139 Å²	139	56.3 Å²	56.3	53%	0.525	26%	0.264	S	S	.	.	H	α-helix	trans	-53.1	-48.6	-174.3	-63	-180	-175.8	156.3	2.2	113.2	K243 F247 L248 I249 E435	K243-R245 PolarHBondContact O-N 3.48Å; R245-F247 VanDerWaalsContact C-N 3.27Å; R245-F247 PolarHBondContact O-N 3.38Å; R245-L248 PolarHBondContact O-N 2.86Å; R245-I249 WeakPolarHBondContact O-CG1 3.48Å; R245-I249 PolarHBondContact O-N 3.41Å; R245-I249 VanDerWaalsContact O-N 3.15Å; R245-E435 IonicContact CZ-OE1 3.79Å; R245-E435 IonicContact NH1-OE1 2.77Å; R245-E435 PolarHBondContact NH1-OE1 2.91Å
246	G	89.9	Confident	87.7	Confident	1 Å²	1	51.3 Å²	51.3	1%	0.01	25%	0.245	C	C	.	.	H	α-helix	trans	-64.2	-31.4	179.4	0	0	0	0	0	113.3	H244 Y250	H244-G246 PolarHBondContact O-N 3.45Å; G246-Y250 WeakPolarHBondContact O-CB 3.16Å; G246-Y250 PolarHBondContact O-N 3.31Å; G246-Y250 VanDerWaalsContact O-N 3.12Å
247	F	92.6	Very high	89.6	Confident	0 Å²	0	46.7 Å²	46.7	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-72.4	-38.7	177.2	177.5	-101.3	0	0	0	111.3	L241 F242 H244 R245 Y250 L251 L362 V366 A374 L377 V378	L241-F247 HydrophobicContact CB-CD1 4.01Å; L241-F247 HydrophobicContact CB-CE1 4Å; L241-F247 HydrophobicContact CB-CG 4.47Å; L241-F247 HydrophobicContact CB-CZ 4.44Å; L241-F247 VanDerWaalsContact O-CD1 3.28Å; L241-F247 WeakPolarHBondContact O-CD1 3.43Å; F242-F247 HydrophobicContact CD1-CE1 4.37Å; F242-F247 HydrophobicContact CE1-CE1 4.38Å; H244-F247 HydrophobicContact CB-CB 3.96Å; H244-F247 PolarHBondContact ND1-N 2.92Å; H244-F247 WeakPolarHBondContact O-CB 3.41Å; H244-F247 PolarHBondContact O-N 3.47Å; R245-F247 VanDerWaalsContact C-N 3.27Å; R245-F247 PolarHBondContact O-N 3.38Å; F247-Y250 PolarHBondContact O-N 2.87Å; F247-L251 HydrophobicContact CE1-CD2 4.11Å; F247-L251 HydrophobicContact CZ-CD2 4.45Å; F247-L251 VanDerWaalsContact O-CB 3.25Å; F247-L251 WeakPolarHBondContact O-CB 3.27Å; F247-L251 PolarHBondContact O-N 3.16Å; F247-L362 HydrophobicContact CD2-CD1 3.97Å; F247-L362 HydrophobicContact CE2-CD1 3.98Å; F247-V366 HydrophobicContact CB-CG2 4.45Å; F247-V366 HydrophobicContact CD2-CG2 3.78Å; F247-V366 HydrophobicContact CG-CG2 4.47Å; F247-A374 HydrophobicContact CE2-CB 4Å; F247-L377 HydrophobicContact CE1-CD2 3.98Å; F247-L377 HydrophobicContact CZ-CB 4.31Å; F247-L377 HydrophobicContact CZ-CD2 4Å; F247-V378 HydrophobicContact CE2-CG2 3.57Å; F247-V378 HydrophobicContact CZ-CG2 3.83Å
248	L	94.1	Very high	91	Very high	76 Å²	76	45.6 Å²	45.6	40%	0.398	22%	0.22	S	C	.	.	H	α-helix	trans	-65.5	-42	176.8	-89.9	77.8	0	0	0	112.5	F242 H244 R245 L251 S252	F242-L248 VanDerWaalsContact C-CD1 3.45Å; F242-L248 WeakPolarHBondContact O-CD1 3.37Å; H244-L248 VanDerWaalsContact O-CD1 3.22Å; H244-L248 WeakPolarHBondContact O-CD1 3.3Å; H244-L248 PolarHBondContact O-N 3.08Å; H244-L248 VanDerWaalsContact O-N 3.1Å; R245-L248 PolarHBondContact O-N 2.86Å; L248-L251 PolarHBondContact O-N 3.4Å; L248-S252 WeakPolarHBondContact O-CB 3.34Å; L248-S252 PolarHBondContact O-N 2.89Å; L248-S252 PolarHBondContact O-OG 3.35Å
249	I	94.4	Very high	92	Very high	29 Å²	29	46 Å²	46	15%	0.149	22%	0.223	C	C	.	.	H	α-helix	trans	-62.6	-47.2	177.1	-66.3	166.8	0	0	0	109.7	R245 S252 G253 L421 N428	R245-I249 WeakPolarHBondContact O-CG1 3.48Å; R245-I249 PolarHBondContact O-N 3.41Å; R245-I249 VanDerWaalsContact O-N 3.15Å; I249-S252 PolarHBondContact O-OG 2.89Å; I249-G253 PolarHBondContact O-N 3.44Å; I249-L421 HydrophobicContact CG2-CD2 4.41Å; I249-L421 WeakPolarHBondContact O-CD2 3.45Å; I249-N428 HydrophobicContact CD1-CB 3.96Å
250	Y	94.9	Very high	92.7	Very high	3 Å²	3	41.5 Å²	41.5	1%	0.012	20%	0.203	C	C	.	.	H	α-helix	trans	-58.4	-50.1	175.2	175.4	-90.6	0	0	0	112.1	G246 F247 G253 N254 F317 L358 T361 L362 L365 V378	G246-Y250 WeakPolarHBondContact O-CB 3.16Å; G246-Y250 PolarHBondContact O-N 3.31Å; G246-Y250 VanDerWaalsContact O-N 3.12Å; F247-Y250 PolarHBondContact O-N 2.87Å; Y250-G253 PolarHBondContact O-N 3.03Å; Y250-N254 WeakPolarHBondContact CE1-ND2 3.47Å; Y250-N254 WeakPolarHBondContact O-CB 3.44Å; Y250-N254 PolarHBondContact O-N 3.08Å; Y250-N254 PolarHBondContact O-OD1 3.2Å; Y250-N254 PolarHBondContact OH-ND2 3.49Å; Y250-N254 VanDerWaalsContact OH-ND2 3.09Å; Y250-F317 HydrophobicContact CD2-CE1 4.38Å; Y250-F317 AromaticContact CE2-CE1 3.99Å; Y250-F317 HydrophobicContact CE2-CE1 3.99Å; Y250-F317 HydrophobicContact CE2-CZ 4.41Å; Y250-L358 WeakPolarHBondContact OH-CD1 3.2Å; Y250-L358 WeakPolarHBondContact OH-CG 3.28Å; Y250-L358 PolarHBondContact OH-O 2.84Å; Y250-L358 VanDerWaalsContact OH-O 3.13Å; Y250-T361 HydrophobicContact CD2-CG2 4.11Å; Y250-T361 HydrophobicContact CE2-CG2 4.16Å; Y250-L362 HydrophobicContact CD1-CD1 4.01Å; Y250-L362 HydrophobicContact CE1-CB 4.21Å; Y250-L362 HydrophobicContact CE1-CD1 3.81Å; Y250-L362 HydrophobicContact CE1-CD2 4.47Å; Y250-L362 HydrophobicContact CE1-CG 4.38Å; Y250-L362 HydrophobicContact CE2-CB 4.46Å; Y250-L365 HydrophobicContact CD2-CD1 3.86Å; Y250-L365 HydrophobicContact CG-CD1 3.93Å; Y250-V378 HydrophobicContact CE1-CG1 4.36Å; Y250-V378 HydrophobicContact CE1-CG2 4.16Å
251	L	95.1	Very high	93.2	Very high	14 Å²	14	39.5 Å²	39.5	7%	0.073	19%	0.188	C	C	.	.	H	α-helix	trans	-63.4	-45.9	-177.9	-175.6	67.3	0	0	0	112.1	F242 F247 L248 G253 N254 V255 V378 V381	F242-L251 HydrophobicContact CD1-CD2 4.36Å; F242-L251 HydrophobicContact CE1-CD2 3.54Å; F242-L251 HydrophobicContact CZ-CD2 4.35Å; F247-L251 HydrophobicContact CE1-CD2 4.11Å; F247-L251 HydrophobicContact CZ-CD2 4.45Å; F247-L251 VanDerWaalsContact O-CB 3.25Å; F247-L251 WeakPolarHBondContact O-CB 3.27Å; F247-L251 PolarHBondContact O-N 3.16Å; L248-L251 PolarHBondContact O-N 3.4Å; L251-G253 PolarHBondContact O-N 2.92Å; L251-N254 PolarHBondContact O-N 3.04Å; L251-V255 VanDerWaalsContact O-CG2 3.28Å; L251-V255 WeakPolarHBondContact O-CG2 3.31Å; L251-V255 PolarHBondContact O-N 3.45Å; L251-V378 HydrophobicContact CD1-CB 4.43Å; L251-V378 HydrophobicContact CD1-CG2 4.01Å; L251-V381 HydrophobicContact CD1-CB 4.02Å; L251-V381 HydrophobicContact CD1-CG1 3.96Å; L251-V381 HydrophobicContact CD2-CG1 4.37Å; L251-V381 HydrophobicContact CD2-CG2 4.47Å; L251-V381 HydrophobicContact CG-CG1 4.27Å
252	S	96	Very high	93.6	Very high	41 Å²	41	39.7 Å²	39.7	29%	0.287	19%	0.189	S	C	.	.	H	α-helix	trans	-62.6	-42.3	178.4	55	0	0	0	0	112.2	L248 I249 V255 I256 W420	L248-S252 WeakPolarHBondContact O-CB 3.34Å; L248-S252 PolarHBondContact O-N 2.89Å; L248-S252 PolarHBondContact O-OG 3.35Å; I249-S252 PolarHBondContact O-OG 2.89Å; S252-V255 PolarHBondContact O-N 2.97Å; S252-I256 WeakPolarHBondContact O-CG1 3.37Å; S252-I256 PolarHBondContact O-N 3.01Å; S252-W420 PolarHBondContact OG-NE1 3.01Å
253	G	96.2	Very high	93.8	Very high	0 Å²	0	36 Å²	36	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-66.2	-41.4	175.9	0	0	0	0	0	113.4	I249 Y250 L251 V255 I256 M257	I249-G253 PolarHBondContact O-N 3.44Å; Y250-G253 PolarHBondContact O-N 3.03Å; L251-G253 PolarHBondContact O-N 2.92Å; G253-V255 VanDerWaalsContact C-N 3.34Å; G253-V255 PolarHBondContact O-N 3.31Å; G253-I256 PolarHBondContact O-N 2.89Å; G253-M257 WeakPolarHBondContact O-CB 3.3Å; G253-M257 PolarHBondContact O-N 2.91Å
254	N	95.5	Very high	94.3	Very high	0 Å²	0	27.1 Å²	27.1	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-61.3	-42.8	174.7	-81	15.7	0	0	0	111.9	Y250 L251 I256 M257 F258 L358 E382	Y250-N254 WeakPolarHBondContact CE1-ND2 3.47Å; Y250-N254 WeakPolarHBondContact O-CB 3.44Å; Y250-N254 PolarHBondContact O-N 3.08Å; Y250-N254 PolarHBondContact O-OD1 3.2Å; Y250-N254 PolarHBondContact OH-ND2 3.49Å; Y250-N254 VanDerWaalsContact OH-ND2 3.09Å; L251-N254 PolarHBondContact O-N 3.04Å; N254-I256 VanDerWaalsContact C-N 3.32Å; N254-I256 PolarHBondContact O-N 2.73Å; N254-M257 PolarHBondContact O-N 3.48Å; N254-F258 HydrophobicContact CB-CD2 4.11Å; N254-F258 HydrophobicContact CB-CE2 4.18Å; N254-F258 WeakPolarHBondContact O-CB 3.31Å; N254-F258 WeakPolarHBondContact O-CD2 3.49Å; N254-F258 PolarHBondContact O-N 2.9Å; N254-L358 WeakPolarHBondContact ND2-CD1 3.47Å; N254-E382 PolarHBondContact ND2-OE1 3.19Å
255	V	96.3	Very high	94.6	Very high	46 Å²	46	23.3 Å²	23.3	28%	0.279	12%	0.116	S	C	.	.	H	α-helix	trans	-57.9	-44.8	177.6	164.8	0	0	0	0	111.6	L251 S252 G253 V381 P385	L251-V255 VanDerWaalsContact O-CG2 3.28Å; L251-V255 WeakPolarHBondContact O-CG2 3.31Å; L251-V255 PolarHBondContact O-N 3.45Å; S252-V255 PolarHBondContact O-N 2.97Å; G253-V255 VanDerWaalsContact C-N 3.34Å; G253-V255 PolarHBondContact O-N 3.31Å; V255-V381 HydrophobicContact CG2-CG1 3.56Å; V255-P385 HydrophobicContact CB-CG 4.21Å; V255-P385 HydrophobicContact CG1-CG 3.71Å; V255-P385 HydrophobicContact CG2-CG 4.42Å; V255-P385 WeakPolarHBondContact O-CB 3.43Å; V255-P385 VanDerWaalsContact O-CG 3.29Å; V255-P385 WeakPolarHBondContact O-CG 3.47Å
256	I	96.8	Very high	94.7	Very high	64 Å²	64	16.8 Å²	16.8	33%	0.328	9%	0.092	S	C	.	.	H	α-helix	trans	-66.8	-45.8	177.1	-58.6	165.2	0	0	0	110.1	S252 G253 N254 F258 L259 I413 A417 W420	S252-I256 WeakPolarHBondContact O-CG1 3.37Å; S252-I256 PolarHBondContact O-N 3.01Å; G253-I256 PolarHBondContact O-N 2.89Å; N254-I256 VanDerWaalsContact C-N 3.32Å; N254-I256 PolarHBondContact O-N 2.73Å; I256-F258 PolarHBondContact O-N 2.69Å; I256-L259 WeakPolarHBondContact O-CB 3.4Å; I256-L259 PolarHBondContact O-N 2.81Å; I256-I413 HydrophobicContact CG2-CG2 4.18Å; I256-I413 WeakPolarHBondContact O-CG2 3.38Å; I256-A417 HydrophobicContact CB-CB 3.99Å; I256-A417 HydrophobicContact CG2-CB 3.82Å; I256-W420 HydrophobicContact CD1-CG 4.36Å
257	M	96.6	Very high	94.9	Very high	0 Å²	0	17 Å²	17	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-59	-50.3	-179.8	-178.8	-165.5	71.2	0	0	111.8	G253 N254 L259 G260 F261 I321 V354 A417	G253-M257 WeakPolarHBondContact O-CB 3.3Å; G253-M257 PolarHBondContact O-N 2.91Å; N254-M257 PolarHBondContact O-N 3.48Å; M257-L259 PolarHBondContact O-N 3.03Å; M257-L259 VanDerWaalsContact O-N 3.15Å; M257-G260 PolarHBondContact O-N 2.92Å; M257-F261 HydrophobicContact CG-CB 4.45Å; M257-F261 HydrophobicContact CG-CD2 4.41Å; M257-F261 WeakPolarHBondContact O-CB 3.42Å; M257-F261 PolarHBondContact O-N 3.07Å; M257-I321 HydrophobicContact CG-CG2 4.04Å; M257-I321 HydrophobicContact SD-CD1 3.61Å; M257-I321 HydrophobicContact SD-CG1 3.72Å; M257-I321 HydrophobicContact SD-CG2 4.07Å; M257-V354 HydrophobicContact CE-CG1 4.42Å; M257-V354 HydrophobicContact SD-CG1 4.08Å; M257-A417 HydrophobicContact CB-CB 3.78Å
258	F	95.6	Very high	95	Very high	4 Å²	4	17 Å²	17	2%	0.018	9%	0.093	C	C	.	.	H	α-helix	trans	-65	-19.9	-174.2	-83.8	-65.5	0	0	0	113.8	N254 I256 G260 F261 F262 L358 E382 P385 V386	N254-F258 HydrophobicContact CB-CD2 4.11Å; N254-F258 HydrophobicContact CB-CE2 4.18Å; N254-F258 WeakPolarHBondContact O-CB 3.31Å; N254-F258 WeakPolarHBondContact O-CD2 3.49Å; N254-F258 PolarHBondContact O-N 2.9Å; I256-F258 PolarHBondContact O-N 2.69Å; F258-G260 VanDerWaalsContact C-N 3.29Å; F258-G260 PolarHBondContact O-N 3.1Å; F258-F261 HydrophobicContact CD1-CB 4.28Å; F258-F261 AromaticContact CD1-CD1 3.99Å; F258-F261 HydrophobicContact CD1-CD1 3.99Å; F258-F261 HydrophobicContact CD1-CG 4.49Å; F258-F261 AromaticContact CE1-CD1 3.83Å; F258-F261 HydrophobicContact CE1-CD1 3.83Å; F258-F261 HydrophobicContact CE1-CE1 4.28Å; F258-F262 AromaticContact CD1-CD2 3.93Å; F258-F262 HydrophobicContact CD1-CD2 3.93Å; F258-F262 AromaticContact CD1-CE2 3.38Å; F258-F262 HydrophobicContact CD1-CE2 3.38Å; F258-F262 HydrophobicContact CD1-CZ 4.24Å; F258-F262 HydrophobicContact CE1-CD2 4.42Å; F258-F262 AromaticContact CE1-CE2 3.5Å; F258-F262 HydrophobicContact CE1-CE2 3.5Å; F258-F262 VanDerWaalsContact CE1-CE2 3.5Å; F258-F262 AromaticContact CE1-CZ 3.9Å; F258-F262 HydrophobicContact CE1-CZ 3.9Å; F258-L358 HydrophobicContact CZ-CD2 4.24Å; F258-E382 HydrophobicContact CD2-CB 4.3Å; F258-E382 HydrophobicContact CD2-CG 3.68Å; F258-E382 HydrophobicContact CE2-CG 3.89Å; F258-E382 WeakPolarHBondContact CE2-OE1 3.48Å; F258-P385 HydrophobicContact CB-CB 3.95Å; F258-V386 HydrophobicContact CB-CG2 4.16Å; F258-V386 HydrophobicContact CD1-CG2 4.11Å; F258-V386 HydrophobicContact CG-CG2 4.32Å
259	L	95.3	Very high	94.9	Very high	57 Å²	57	13.4 Å²	13.4	30%	0.298	7%	0.074	S	C	.	.	H	α-helix	trans	-62.8	-35.4	173	-166.6	70.8	0	0	0	112	I256 M257 P385 L388 G389 I413	I256-L259 WeakPolarHBondContact O-CB 3.4Å; I256-L259 PolarHBondContact O-N 2.81Å; M257-L259 PolarHBondContact O-N 3.03Å; M257-L259 VanDerWaalsContact O-N 3.15Å; L259-P385 HydrophobicContact CB-CB 4.27Å; L259-P385 HydrophobicContact CD1-CB 4.41Å; L259-L388 HydrophobicContact CD1-CB 4.44Å; L259-G389 WeakPolarHBondContact O-CA 3.22Å; L259-I413 HydrophobicContact CB-CG2 4.33Å; L259-I413 HydrophobicContact CD2-CD1 4.33Å
260	G	94.2	Very high	94.8	Very high	0 Å²	0	12.3 Å²	12.3	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-109.1	-2.5	-180	0	0	0	0	0	115.1	M257 F258 P264	M257-G260 PolarHBondContact O-N 2.92Å; F258-G260 VanDerWaalsContact C-N 3.29Å; F258-G260 PolarHBondContact O-N 3.1Å; G260-P264 WeakPolarHBondContact O-CD 3.41Å
261	F	94.6	Very high	94.7	Very high	5 Å²	5	12.3 Å²	12.3	2%	0.022	7%	0.069	C	C	.	.	H	α-helix	trans	-80.4	-38.8	-169.7	-171.5	-113.7	0	0	0	114.2	M257 F258 N324 F351 V354	M257-F261 HydrophobicContact CG-CB 4.45Å; M257-F261 HydrophobicContact CG-CD2 4.41Å; M257-F261 WeakPolarHBondContact O-CB 3.42Å; M257-F261 PolarHBondContact O-N 3.07Å; F258-F261 HydrophobicContact CD1-CB 4.28Å; F258-F261 AromaticContact CD1-CD1 3.99Å; F258-F261 HydrophobicContact CD1-CD1 3.99Å; F258-F261 HydrophobicContact CD1-CG 4.49Å; F258-F261 AromaticContact CE1-CD1 3.83Å; F258-F261 HydrophobicContact CE1-CD1 3.83Å; F258-F261 HydrophobicContact CE1-CE1 4.28Å; F261-N324 WeakPolarHBondContact CE2-ND2 3.22Å; F261-F351 HydrophobicContact CD1-CE2 4.17Å; F261-F351 AromaticContact CE1-CD2 3.83Å; F261-F351 HydrophobicContact CE1-CD2 3.83Å; F261-F351 AromaticContact CE1-CE2 3.31Å; F261-F351 HydrophobicContact CE1-CE2 3.31Å; F261-F351 HydrophobicContact CE1-CZ 4.02Å; F261-F351 HydrophobicContact CE2-CD2 4.2Å; F261-F351 HydrophobicContact CE2-CE2 4.49Å; F261-F351 AromaticContact CZ-CD2 3.49Å; F261-F351 HydrophobicContact CZ-CD2 3.49Å; F261-F351 VanDerWaalsContact CZ-CD2 3.49Å; F261-F351 AromaticContact CZ-CE2 3.5Å; F261-F351 HydrophobicContact CZ-CE2 3.5Å; F261-F351 HydrophobicContact CZ-CG 4.33Å; F261-F351 HydrophobicContact CZ-CZ 4.34Å; F261-V354 HydrophobicContact CE2-CB 4.22Å; F261-V354 HydrophobicContact CE2-CG1 3.96Å; F261-V354 HydrophobicContact CE2-CG2 4.41Å; F261-V354 HydrophobicContact CZ-CB 4.18Å; F261-V354 HydrophobicContact CZ-CG1 3.87Å
262	F	93.2	Very high	94.6	Very high	8 Å²	8	11.6 Å²	11.6	4%	0.035	7%	0.065	C	C	.	.	S	Bend	trans	-93.3	-23.5	-174.6	-73.6	-67.9	0	0	0	114.3	L66 F258 I265 I266 F351 V386 P390	L66-F262 HydrophobicContact CD2-CD1 3.8Å; L66-F262 HydrophobicContact CD2-CD2 4.15Å; L66-F262 HydrophobicContact CD2-CE1 3.81Å; L66-F262 HydrophobicContact CD2-CE2 4.12Å; L66-F262 HydrophobicContact CD2-CG 3.98Å; L66-F262 HydrophobicContact CD2-CZ 3.98Å; F258-F262 AromaticContact CD1-CD2 3.93Å; F258-F262 HydrophobicContact CD1-CD2 3.93Å; F258-F262 AromaticContact CD1-CE2 3.38Å; F258-F262 HydrophobicContact CD1-CE2 3.38Å; F258-F262 HydrophobicContact CD1-CZ 4.24Å; F258-F262 HydrophobicContact CE1-CD2 4.42Å; F258-F262 AromaticContact CE1-CE2 3.5Å; F258-F262 HydrophobicContact CE1-CE2 3.5Å; F258-F262 VanDerWaalsContact CE1-CE2 3.5Å; F258-F262 AromaticContact CE1-CZ 3.9Å; F258-F262 HydrophobicContact CE1-CZ 3.9Å; F262-I265 HydrophobicContact CD1-CG2 4.28Å; F262-I265 WeakPolarHBondContact O-CG2 3.46Å; F262-I265 PolarHBondContact O-N 2.97Å; F262-I266 HydrophobicContact CB-CD1 4.17Å; F262-I266 WeakPolarHBondContact O-CD1 3.22Å; F262-I266 WeakPolarHBondContact O-CG1 3.17Å; F262-I266 PolarHBondContact O-N 2.95Å; F262-I266 VanDerWaalsContact O-N 3.1Å; F262-F351 HydrophobicContact CE1-CE2 4.36Å; F262-F351 HydrophobicContact CE1-CZ 4.37Å; F262-V386 HydrophobicContact CD2-CG1 4.17Å; F262-V386 HydrophobicContact CD2-CG2 3.82Å; F262-V386 HydrophobicContact CE2-CG1 4.36Å; F262-V386 HydrophobicContact CE2-CG2 3.7Å; F262-P390 HydrophobicContact CB-CG 4.46Å
263	A	94.9	Very high	94.4	Very high	0 Å²	0	10.2 Å²	10.2	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-59.8	-45.9	-179.1	0	0	0	0	0	112.8	I265 I266 F267 P390 A393 M406	A263-I265 VanDerWaalsContact C-N 3.33Å; A263-I265 PolarHBondContact O-N 2.87Å; A263-I266 PolarHBondContact O-N 3.28Å; A263-I266 VanDerWaalsContact O-N 3.14Å; A263-F267 HydrophobicContact CB-CD2 4.29Å; A263-F267 HydrophobicContact CB-CE2 4.47Å; A263-F267 VanDerWaalsContact O-CD2 3.32Å; A263-F267 WeakPolarHBondContact O-CD2 3.07Å; A263-F267 PolarHBondContact O-N 3.3Å; A263-P390 HydrophobicContact CB-CB 4.38Å; A263-P390 HydrophobicContact CB-CG 4.41Å; A263-A393 HydrophobicContact CB-CB 3.49Å; A263-A393 VanDerWaalsContact CB-CB 3.49Å; A263-M406 HydrophobicContact CB-SD 4.45Å
264	P	95.9	Very high	94	Very high	0 Å²	0	13.8 Å²	13.8	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-56.5	-39.3	177.3	-32	40.4	0	0	0	114.7	G260 L268 H328 F347 Y407 C410	G260-P264 WeakPolarHBondContact O-CD 3.41Å; P264-L268 WeakPolarHBondContact O-CB 3.16Å; P264-L268 PolarHBondContact O-N 2.91Å; P264-H328 WeakPolarHBondContact CB-CE1 3.42Å; P264-F347 HydrophobicContact CB-CE1 4.33Å; P264-F347 HydrophobicContact CB-CZ 4.28Å; P264-Y407 HydrophobicContact CB-CD1 4.05Å; P264-Y407 HydrophobicContact CB-CE1 3.66Å; P264-Y407 HydrophobicContact CG-CD1 4.36Å; P264-Y407 HydrophobicContact CG-CE1 4.41Å; P264-Y407 PolarHBondContact O-OH 3.47Å; P264-C410 HydrophobicContact CG-CB 3.74Å
265	I	94	Very high	93.8	Very high	2 Å²	2	16.8 Å²	16.8	1%	0.01	9%	0.087	C	C	.	.	H	α-helix	trans	-75	-35.3	178.1	-174.8	165.7	0	0	0	112.1	K38 F262 A263 L286 M289 F347	K38-I265 HydrophobicContact CD-CD1 3.78Å; K38-I265 HydrophobicContact CG-CD1 4.2Å; F262-I265 HydrophobicContact CD1-CG2 4.28Å; F262-I265 WeakPolarHBondContact O-CG2 3.46Å; F262-I265 PolarHBondContact O-N 2.97Å; A263-I265 VanDerWaalsContact C-N 3.33Å; A263-I265 PolarHBondContact O-N 2.87Å; I265-L286 HydrophobicContact CG1-CD2 4.01Å; I265-M289 HydrophobicContact CB-CE 4.48Å; I265-M289 HydrophobicContact CD1-CE 4.11Å; I265-M289 HydrophobicContact CD1-SD 3.46Å; I265-M289 WeakPolarHBondContact CD1-SD 3.33Å; I265-M289 HydrophobicContact CG1-CE 3.92Å; I265-M289 HydrophobicContact CG1-SD 3.96Å; I265-F347 HydrophobicContact CB-CE1 3.74Å; I265-F347 HydrophobicContact CB-CZ 3.77Å; I265-F347 HydrophobicContact CG1-CE1 4.4Å
266	I	93.4	Very high	93.5	Very high	3 Å²	3	17.9 Å²	17.9	2%	0.015	11%	0.107	C	C	.	.	H	α-helix	trans	-66.2	-44.1	178.8	-73.8	162.6	0	0	0	110.5	T41 F44 F262 A263 P390	T41-I266 WeakPolarHBondContact CB-O 3.42Å; T41-I266 HydrophobicContact CG2-CB 4.22Å; T41-I266 HydrophobicContact CG2-CG1 4.17Å; T41-I266 HydrophobicContact CG2-CG2 3.9Å; T41-I266 PolarHBondContact OG1-O 3.18Å; F44-I266 HydrophobicContact CD2-CG2 4.29Å; F44-I266 HydrophobicContact CE2-CG2 3.94Å; F262-I266 HydrophobicContact CB-CD1 4.17Å; F262-I266 WeakPolarHBondContact O-CD1 3.22Å; F262-I266 WeakPolarHBondContact O-CG1 3.17Å; F262-I266 PolarHBondContact O-N 2.95Å; F262-I266 VanDerWaalsContact O-N 3.1Å; A263-I266 PolarHBondContact O-N 3.28Å; A263-I266 VanDerWaalsContact O-N 3.14Å; I266-P390 HydrophobicContact CD1-CB 3.85Å; I266-P390 HydrophobicContact CD1-CG 3.48Å; I266-P390 VanDerWaalsContact CD1-CG 3.48Å
267	F	94.4	Very high	93.4	Very high	5 Å²	5	16 Å²	16	2%	0.022	10%	0.098	C	C	.	.	S	Bend	trans	-88.3	1.3	-176.6	-70.6	-64.6	0	0	0	114.7	A59 A263 P270 Y271 P390 A393 Y403 M406	A59-F267 HydrophobicContact CB-CE1 4.39Å; A59-F267 HydrophobicContact CB-CE2 4.31Å; A59-F267 HydrophobicContact CB-CZ 3.63Å; A263-F267 HydrophobicContact CB-CD2 4.29Å; A263-F267 HydrophobicContact CB-CE2 4.47Å; A263-F267 VanDerWaalsContact O-CD2 3.32Å; A263-F267 WeakPolarHBondContact O-CD2 3.07Å; A263-F267 PolarHBondContact O-N 3.3Å; F267-P270 WeakPolarHBondContact O-CD 3.43Å; F267-Y271 WeakPolarHBondContact O-CB 3.37Å; F267-Y271 PolarHBondContact O-N 3.47Å; F267-P390 WeakPolarHBondContact CE2-O 3.21Å; F267-A393 HydrophobicContact CE2-CB 4.24Å; F267-Y403 HydrophobicContact CB-CD1 4.3Å; F267-Y403 HydrophobicContact CB-CE1 4.01Å; F267-Y403 AromaticContact CD1-CE1 3.89Å; F267-Y403 HydrophobicContact CD1-CE1 3.89Å; F267-Y403 HydrophobicContact CG-CE1 4.17Å; F267-M406 HydrophobicContact CB-CE 3.63Å; F267-M406 HydrophobicContact CD2-CE 3.98Å; F267-M406 HydrophobicContact CD2-SD 4.28Å; F267-M406 HydrophobicContact CG-CE 4.08Å
268	L	94.3	Very high	93.2	Very high	0 Å²	0	20.1 Å²	20.1	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-61.1	-49.3	-178.6	-177.4	56	0	0	0	113.2	P264 Y271 A272 L285 L286 M289 Y343 Y407	P264-L268 WeakPolarHBondContact O-CB 3.16Å; P264-L268 PolarHBondContact O-N 2.91Å; L268-Y271 PolarHBondContact O-N 2.92Å; L268-A272 PolarHBondContact O-N 3.46Å; L268-L285 HydrophobicContact CD2-CB 4.2Å; L268-L285 HydrophobicContact CG-CB 4.41Å; L268-L286 HydrophobicContact CB-CD2 4.3Å; L268-L286 HydrophobicContact CD2-CD2 4.18Å; L268-M289 HydrophobicContact CD2-CE 3.31Å; L268-Y343 HydrophobicContact CD1-CD1 4.12Å; L268-Y343 HydrophobicContact CD1-CE1 3.76Å; L268-Y407 WeakPolarHBondContact CA-OH 3.36Å
269	A	92.1	Very high	93	Very high	1 Å²	1	23.5 Å²	23.5	1%	0.008	14%	0.136	C	C	.	.	H	α-helix	trans	-67.5	-46.9	179	0	0	0	0	0	112.2	Y271 A272 K273 L286	A269-Y271 VanDerWaalsContact C-N 3.31Å; A269-Y271 PolarHBondContact O-N 3.28Å; A269-A272 PolarHBondContact O-N 3.15Å; A269-K273 WeakPolarHBondContact O-CG 3.48Å; A269-K273 PolarHBondContact O-N 3.29Å; A269-L286 HydrophobicContact CB-CD1 4.05Å
270	P	91.3	Very high	92.8	Very high	5 Å²	5	24.6 Å²	24.6	3%	0.032	14%	0.136	C	C	.	.	H	α-helix	trans	-54.9	-42.4	171.6	-28.7	35	0	0	0	113.9	F44 F267 K273 D274 Y403	F44-P270 HydrophobicContact CB-CG 4.43Å; F267-P270 WeakPolarHBondContact O-CD 3.43Å; P270-K273 PolarHBondContact O-N 2.96Å; P270-D274 WeakPolarHBondContact O-CB 3.34Å; P270-D274 PolarHBondContact O-N 3.31Å; P270-Y403 WeakPolarHBondContact CB-OH 3.39Å
271	Y	92.5	Very high	92.8	Very high	3 Å²	3	25.8 Å²	25.8	1%	0.012	15%	0.145	C	C	.	.	H	α-helix	trans	-62.7	-45.7	178.4	176.3	-127.5	0	0	0	112.7	F267 L268 A269 K273 D274 Q275 L340 Y403 Y407	F267-Y271 WeakPolarHBondContact O-CB 3.37Å; F267-Y271 PolarHBondContact O-N 3.47Å; L268-Y271 PolarHBondContact O-N 2.92Å; A269-Y271 VanDerWaalsContact C-N 3.31Å; A269-Y271 PolarHBondContact O-N 3.28Å; Y271-K273 PolarHBondContact O-N 3.2Å; Y271-D274 WeakPolarHBondContact O-CB 3.49Å; Y271-D274 PolarHBondContact O-N 3.3Å; Y271-D274 VanDerWaalsContact O-N 3.17Å; Y271-Q275 HydrophobicContact CE2-CG 4.2Å; Y271-Q275 VanDerWaalsContact CZ-NE2 3.26Å; Y271-Q275 PolarHBondContact O-N 3.49Å; Y271-Q275 PolarHBondContact OH-NE2 3.2Å; Y271-L340 HydrophobicContact CD1-CD2 4.14Å; Y271-L340 HydrophobicContact CE1-CD2 3.81Å; Y271-Y403 HydrophobicContact CD2-CD1 4.29Å; Y271-Y403 AromaticContact CD2-CD2 3.79Å; Y271-Y403 HydrophobicContact CD2-CD2 3.79Å; Y271-Y403 AromaticContact CD2-CG 3.54Å; Y271-Y403 HydrophobicContact CD2-CG 3.54Å; Y271-Y403 HydrophobicContact CE2-CG 4.3Å; Y271-Y403 HydrophobicContact CG-CG 4.23Å; Y271-Y407 AromaticContact CD1-CE2 3.62Å; Y271-Y407 HydrophobicContact CD1-CE2 3.62Å; Y271-Y407 HydrophobicContact CD2-CE2 4.32Å; Y271-Y407 HydrophobicContact CE1-CD2 4.49Å; Y271-Y407 AromaticContact CE1-CE2 3.95Å; Y271-Y407 HydrophobicContact CE1-CE2 3.95Å; Y271-Y407 AromaticContact CG-CE2 3.8Å; Y271-Y407 HydrophobicContact CG-CE2 3.8Å
272	A	93.1	Very high	92.7	Very high	0 Å²	0	25.5 Å²	25.5	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-62.1	-44	176.3	0	0	0	0	0	111.5	L268 A269 D274 Q275 G276 I277 A282 L285 L340	L268-A272 PolarHBondContact O-N 3.46Å; A269-A272 PolarHBondContact O-N 3.15Å; A272-D274 VanDerWaalsContact C-N 3.26Å; A272-D274 PolarHBondContact O-N 3.16Å; A272-Q275 PolarHBondContact O-N 3.29Å; A272-G276 PolarHBondContact O-N 2.86Å; A272-I277 HydrophobicContact CB-CB 4.41Å; A272-I277 HydrophobicContact CB-CD1 4.08Å; A272-I277 VanDerWaalsContact O-CB 3.32Å; A272-I277 WeakPolarHBondContact O-CB 3.4Å; A272-I277 PolarHBondContact O-N 3.19Å; A272-I277 VanDerWaalsContact O-N 3.13Å; A272-A282 HydrophobicContact CB-CB 3.77Å; A272-L285 HydrophobicContact CB-CD1 3.62Å; A272-L340 HydrophobicContact CB-CD1 4.22Å
273	K	91.4	Very high	92.6	Very high	12 Å²	12	25.1 Å²	25.1	5%	0.052	14%	0.142	C	C	.	.	H	α-helix	trans	-62.8	-33.6	175.5	-68.2	-179	-179.1	-176.6	0	111.8	V42 K45 E46 A269 P270 Y271 G276 E279 A282	V42-K273 PolarHBondContact O-NZ 3.41Å; K45-K273 HydrophobicContact CB-CD 4.27Å; K45-K273 HydrophobicContact CD-CB 3.43Å; K45-K273 VanDerWaalsContact CD-CB 3.43Å; K45-K273 HydrophobicContact CD-CD 3.88Å; K45-K273 HydrophobicContact CD-CG 4.28Å; K45-K273 PolarHBondContact NZ-O 3.45Å; E46-K273 IonicContact OE1-NZ 2.63Å; E46-K273 PolarHBondContact OE1-NZ 3.11Å; E46-K273 IonicContact OE2-NZ 3.53Å; A269-K273 WeakPolarHBondContact O-CG 3.48Å; A269-K273 PolarHBondContact O-N 3.29Å; P270-K273 PolarHBondContact O-N 2.96Å; Y271-K273 PolarHBondContact O-N 3.2Å; K273-G276 PolarHBondContact O-N 3.46Å; K273-E279 HydrophobicContact CD-CG 4.46Å; K273-A282 HydrophobicContact CG-CB 3.78Å
274	D	89.6	Confident	92.7	Very high	74 Å²	74	29.6 Å²	29.6	40%	0.396	16%	0.162	S	C	.	.	H	α-helix	trans	-68.7	-35.3	177.3	-168.9	61.8	0	0	0	112.5	P270 Y271 A272 G276 Y403	P270-D274 WeakPolarHBondContact O-CB 3.34Å; P270-D274 PolarHBondContact O-N 3.31Å; Y271-D274 WeakPolarHBondContact O-CB 3.49Å; Y271-D274 PolarHBondContact O-N 3.3Å; Y271-D274 VanDerWaalsContact O-N 3.17Å; A272-D274 VanDerWaalsContact C-N 3.26Å; A272-D274 PolarHBondContact O-N 3.16Å; D274-G276 PolarHBondContact O-N 3.3Å; D274-G276 VanDerWaalsContact O-N 3.16Å; D274-Y403 HydrophobicContact CB-CD2 4.28Å; D274-Y403 HydrophobicContact CB-CE2 3.85Å
275	Q	90.4	Very high	92.7	Very high	63 Å²	63	29.6 Å²	29.6	29%	0.294	16%	0.162	S	C	.	.	T	Hydrogen-bonded Turn	trans	-71.8	1	170.6	-68.6	-168.6	-22.2	0	0	114.2	Y271 A272 A334	Y271-Q275 HydrophobicContact CE2-CG 4.2Å; Y271-Q275 VanDerWaalsContact CZ-NE2 3.26Å; Y271-Q275 PolarHBondContact O-N 3.49Å; Y271-Q275 PolarHBondContact OH-NE2 3.2Å; A272-Q275 PolarHBondContact O-N 3.29Å; Q275-A334 PolarHBondContact NE2-O 3.41Å
276	G	90.3	Very high	92.7	Very high	69 Å²	69	29.5 Å²	29.5	71%	0.711	16%	0.161	S	C	*	.	T	Hydrogen-bonded Turn	trans	83.7	14.2	179.5	0	0	0	0	0	114.8	A272 K273 D274	A272-G276 PolarHBondContact O-N 2.86Å; K273-G276 PolarHBondContact O-N 3.46Å; D274-G276 PolarHBondContact O-N 3.3Å; D274-G276 VanDerWaalsContact O-N 3.16Å
277	I	93.9	Very high	92.8	Very high	25 Å²	25	30 Å²	30	13%	0.128	16%	0.164	C	C	.	.			trans	-73.3	143.6	172.3	-65.2	158.7	0	0	0	109.4	A272 Y337 L340	A272-I277 HydrophobicContact CB-CB 4.41Å; A272-I277 HydrophobicContact CB-CD1 4.08Å; A272-I277 VanDerWaalsContact O-CB 3.32Å; A272-I277 WeakPolarHBondContact O-CB 3.4Å; A272-I277 PolarHBondContact O-N 3.19Å; A272-I277 VanDerWaalsContact O-N 3.13Å; I277-Y337 HydrophobicContact CD1-CD2 4.14Å; I277-Y337 HydrophobicContact CG2-CD2 3.83Å; I277-Y337 HydrophobicContact CG2-CE2 4.22Å; I277-L340 HydrophobicContact CD1-CD1 3.32Å
278	D	93.6	Very high	92.9	Very high	87 Å²	87	32 Å²	32	47%	0.465	18%	0.175	S	C	.	.			trans	-61.2	151	179.2	71.3	-86.2	0	0	0	112.4	Y280 S281 A282	D278-Y280 VanDerWaalsContact C-N 3.3Å; D278-Y280 PolarHBondContact O-N 3.24Å; D278-Y280 PolarHBondContact OD2-N 3.34Å; D278-S281 VanDerWaalsContact CG-CB 3.4Å; D278-S281 PolarHBondContact O-N 3.25Å; D278-S281 WeakPolarHBondContact OD1-CB 3.34Å; D278-S281 PolarHBondContact OD1-OG 3.38Å; D278-S281 VanDerWaalsContact OD2-CB 3.29Å; D278-S281 WeakPolarHBondContact OD2-CB 3.43Å; D278-S281 PolarHBondContact OD2-N 3.07Å; D278-S281 PolarHBondContact OD2-OG 3.24Å; D278-A282 WeakPolarHBondContact O-CB 3.24Å; D278-A282 PolarHBondContact O-N 3.49Å
279	E	90.1	Very high	92.9	Very high	75 Å²	75	32.1 Å²	32.1	35%	0.35	18%	0.176	S	C	.	.	H	α-helix	trans	-63.2	-35.3	-170.3	-58.6	175	169.7	0	0	113.1	Q166 N170 K273 A283	Q166-E279 HydrophobicContact CG-CB 4.19Å; Q166-E279 PolarHBondContact NE2-OE2 2.97Å; N170-E279 PolarHBondContact OD1-OE2 3.29Å; K273-E279 HydrophobicContact CD-CG 4.46Å; E279-A283 PolarHBondContact O-N 2.83Å; E279-A283 VanDerWaalsContact O-N 3.15Å
280	Y	92.1	Very high	93.1	Very high	79 Å²	79	32.1 Å²	32.1	31%	0.31	18%	0.176	S	C	.	.	H	α-helix	trans	-70	-48.5	177.3	-84.4	-82	0	0	0	111	Q166 Y167 N170 D278 A282 A283 F284	Q166-Y280 HydrophobicContact CB-CD1 4.45Å; Q166-Y280 HydrophobicContact CB-CE1 4.42Å; Q166-Y280 HydrophobicContact CG-CD1 4.19Å; Q166-Y280 HydrophobicContact CG-CD2 4.41Å; Q166-Y280 HydrophobicContact CG-CE1 4.3Å; Q166-Y280 HydrophobicContact CG-CG 4.26Å; Y167-Y280 WeakPolarHBondContact CA-OH 3.28Å; N170-Y280 WeakPolarHBondContact ND2-CE2 3.36Å; D278-Y280 VanDerWaalsContact C-N 3.3Å; D278-Y280 PolarHBondContact O-N 3.24Å; D278-Y280 PolarHBondContact OD2-N 3.34Å; Y280-A282 VanDerWaalsContact C-N 3.27Å; Y280-A282 PolarHBondContact O-N 3.44Å; Y280-A283 WeakPolarHBondContact O-CB 3.45Å; Y280-A283 PolarHBondContact O-N 3.37Å; Y280-A283 VanDerWaalsContact O-N 3.09Å; Y280-F284 WeakPolarHBondContact O-CD2 3.32Å; Y280-F284 PolarHBondContact O-N 2.98Å
281	S	92.9	Very high	93.3	Very high	25 Å²	25	37.4 Å²	37.4	18%	0.175	20%	0.198	C	C	.	.	H	α-helix	trans	-59.2	-38.2	176.5	-68.1	0	0	0	0	112.2	D278 F284 L285 Y337	D278-S281 VanDerWaalsContact CG-CB 3.4Å; D278-S281 PolarHBondContact O-N 3.25Å; D278-S281 WeakPolarHBondContact OD1-CB 3.34Å; D278-S281 PolarHBondContact OD1-OG 3.38Å; D278-S281 VanDerWaalsContact OD2-CB 3.29Å; D278-S281 WeakPolarHBondContact OD2-CB 3.43Å; D278-S281 PolarHBondContact OD2-N 3.07Å; D278-S281 PolarHBondContact OD2-OG 3.24Å; S281-F284 PolarHBondContact O-N 3.23Å; S281-L285 PolarHBondContact O-N 3.15Å; S281-Y337 PolarHBondContact O-OH 3.17Å
282	A	93.1	Very high	93.4	Very high	0 Å²	0	38.8 Å²	38.8	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-62.1	-43.2	173.4	0	0	0	0	0	112.1	A272 K273 D278 Y280 F284 L285	A272-A282 HydrophobicContact CB-CB 3.77Å; K273-A282 HydrophobicContact CG-CB 3.78Å; D278-A282 WeakPolarHBondContact O-CB 3.24Å; D278-A282 PolarHBondContact O-N 3.49Å; Y280-A282 VanDerWaalsContact C-N 3.27Å; Y280-A282 PolarHBondContact O-N 3.44Å; A282-F284 VanDerWaalsContact C-N 3.33Å; A282-L285 WeakPolarHBondContact O-CB 3.48Å; A282-L285 PolarHBondContact O-N 3.05Å
283	A	92.1	Very high	93.5	Very high	0 Å²	0	39.1 Å²	39.1	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-66.9	-33.3	174.3	0	0	0	0	0	112.6	V42 Q166 E279 Y280 L285 L286 S287	V42-A283 HydrophobicContact CG1-CB 4.43Å; V42-A283 HydrophobicContact CG2-CB 4.39Å; Q166-A283 HydrophobicContact CB-CB 4.09Å; E279-A283 PolarHBondContact O-N 2.83Å; E279-A283 VanDerWaalsContact O-N 3.15Å; Y280-A283 WeakPolarHBondContact O-CB 3.45Å; Y280-A283 PolarHBondContact O-N 3.37Å; Y280-A283 VanDerWaalsContact O-N 3.09Å; A283-L285 VanDerWaalsContact C-N 3.28Å; A283-L285 PolarHBondContact O-N 3.45Å; A283-L286 PolarHBondContact O-N 2.91Å; A283-S287 PolarHBondContact O-N 3.33Å; A283-S287 PolarHBondContact O-OG 3.04Å
284	F	95.3	Very high	93.4	Very high	94 Å²	94	41.3 Å²	41.3	41%	0.412	22%	0.22	S	C	.	.	H	α-helix	trans	-64.8	-27.7	175	-79.9	-65.1	0	0	0	112.9	P163 Y280 S281 A282 L286 S287 I288	P163-F284 HydrophobicContact CB-CE1 4.14Å; P163-F284 HydrophobicContact CB-CZ 4.29Å; P163-F284 HydrophobicContact CG-CE1 4.48Å; Y280-F284 WeakPolarHBondContact O-CD2 3.32Å; Y280-F284 PolarHBondContact O-N 2.98Å; S281-F284 PolarHBondContact O-N 3.23Å; A282-F284 VanDerWaalsContact C-N 3.33Å; F284-L286 VanDerWaalsContact C-N 3.35Å; F284-L286 PolarHBondContact O-N 3.32Å; F284-S287 CarbonylContact O-C 3.15Å; F284-S287 WeakPolarHBondContact O-CA 3.37Å; F284-S287 VanDerWaalsContact O-CB 3.31Å; F284-S287 WeakPolarHBondContact O-CB 3.25Å; F284-S287 PolarHBondContact O-N 2.92Å; F284-I288 WeakPolarHBondContact O-CG1 3.39Å; F284-I288 PolarHBondContact O-N 3.04Å
285	L	96	Very high	93.5	Very high	0 Å²	0	43.5 Å²	43.5	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-60.3	-42.8	174.8	-67	172.9	0	0	0	112.4	L268 A272 S281 A282 A283 S287 I288 M289 Y337 L340 V341 A344	L268-L285 HydrophobicContact CD2-CB 4.2Å; L268-L285 HydrophobicContact CG-CB 4.41Å; A272-L285 HydrophobicContact CB-CD1 3.62Å; S281-L285 PolarHBondContact O-N 3.15Å; A282-L285 WeakPolarHBondContact O-CB 3.48Å; A282-L285 PolarHBondContact O-N 3.05Å; A283-L285 VanDerWaalsContact C-N 3.28Å; A283-L285 PolarHBondContact O-N 3.45Å; L285-S287 PolarHBondContact O-N 2.79Å; L285-I288 PolarHBondContact O-N 3.36Å; L285-M289 WeakPolarHBondContact O-CB 3.36Å; L285-M289 PolarHBondContact O-N 2.96Å; L285-Y337 HydrophobicContact CD2-CE2 3.89Å; L285-Y337 HydrophobicContact CG-CE2 4.07Å; L285-L340 HydrophobicContact CD1-CB 4.06Å; L285-L340 HydrophobicContact CD1-CD1 4.22Å; L285-L340 HydrophobicContact CD2-CB 4.07Å; L285-V341 HydrophobicContact CD2-CB 4.47Å; L285-V341 HydrophobicContact CD2-CG2 3.76Å; L285-A344 HydrophobicContact CD2-CB 4.35Å
286	L	94.4	Very high	93.6	Very high	0 Å²	0	40.8 Å²	40.8	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-62.4	-33.8	173.4	-70.8	172.4	0	0	0	111.4	V42 A162 I265 L268 A269 A283 F284 M289 A290	V42-L286 HydrophobicContact CG2-CD1 3.97Å; A162-L286 HydrophobicContact CB-CB 4.09Å; A162-L286 HydrophobicContact CB-CD1 4.44Å; I265-L286 HydrophobicContact CG1-CD2 4.01Å; L268-L286 HydrophobicContact CB-CD2 4.3Å; L268-L286 HydrophobicContact CD2-CD2 4.18Å; A269-L286 HydrophobicContact CB-CD1 4.05Å; A283-L286 PolarHBondContact O-N 2.91Å; F284-L286 VanDerWaalsContact C-N 3.35Å; F284-L286 PolarHBondContact O-N 3.32Å; L286-M289 HydrophobicContact CD2-CE 4.21Å; L286-A290 VanDerWaalsContact O-CB 3.29Å; L286-A290 WeakPolarHBondContact O-CB 3.1Å; L286-A290 PolarHBondContact O-N 2.63Å
287	S	95.6	Very high	93.6	Very high	12 Å²	12	39.1 Å²	39.1	8%	0.084	19%	0.187	C	C	.	.	H	α-helix	trans	-72.6	-43	179.6	-51.4	0	0	0	0	112.6	S159 P163 A283 F284 L285 A290 F291	S159-S287 PolarHBondContact O-OG 3.09Å; P163-S287 VanDerWaalsContact CD-OG 3.31Å; P163-S287 WeakPolarHBondContact CD-OG 3.33Å; A283-S287 PolarHBondContact O-N 3.33Å; A283-S287 PolarHBondContact O-OG 3.04Å; F284-S287 CarbonylContact O-C 3.15Å; F284-S287 WeakPolarHBondContact O-CA 3.37Å; F284-S287 VanDerWaalsContact O-CB 3.31Å; F284-S287 WeakPolarHBondContact O-CB 3.25Å; F284-S287 PolarHBondContact O-N 2.92Å; L285-S287 PolarHBondContact O-N 2.79Å; S287-A290 PolarHBondContact O-N 2.88Å; S287-F291 WeakPolarHBondContact O-CB 3.16Å; S287-F291 PolarHBondContact O-N 3.07Å
288	I	96.2	Very high	93.3	Very high	47 Å²	47	41.5 Å²	41.5	24%	0.241	20%	0.204	C	C	.	.	H	α-helix	trans	-61	-47.9	174.9	-67.7	164.8	0	0	0	109.6	F284 L285 A290 F291 V292 V341 A344 I345	F284-I288 WeakPolarHBondContact O-CG1 3.39Å; F284-I288 PolarHBondContact O-N 3.04Å; L285-I288 PolarHBondContact O-N 3.36Å; I288-A290 VanDerWaalsContact C-N 3.33Å; I288-A290 PolarHBondContact O-N 3.33Å; I288-F291 PolarHBondContact O-N 2.99Å; I288-V292 WeakPolarHBondContact O-CG2 3.48Å; I288-V292 PolarHBondContact O-N 3.37Å; I288-V341 HydrophobicContact CD1-CG1 4.14Å; I288-V341 HydrophobicContact CD1-CG2 4.02Å; I288-A344 HydrophobicContact CG2-CB 4.35Å; I288-I345 HydrophobicContact CG2-CG1 3.84Å
289	M	95.8	Very high	93.2	Very high	3 Å²	3	40.3 Å²	40.3	2%	0.015	20%	0.203	C	C	.	.	H	α-helix	trans	-56.2	-48	175.5	-177.1	-153.8	-54.6	0	0	111.4	I265 L268 L285 L286 F291 V292 D293 A344 F347 G348	I265-M289 HydrophobicContact CB-CE 4.48Å; I265-M289 HydrophobicContact CD1-CE 4.11Å; I265-M289 HydrophobicContact CD1-SD 3.46Å; I265-M289 WeakPolarHBondContact CD1-SD 3.33Å; I265-M289 HydrophobicContact CG1-CE 3.92Å; I265-M289 HydrophobicContact CG1-SD 3.96Å; L268-M289 HydrophobicContact CD2-CE 3.31Å; L285-M289 WeakPolarHBondContact O-CB 3.36Å; L285-M289 PolarHBondContact O-N 2.96Å; L286-M289 HydrophobicContact CD2-CE 4.21Å; M289-F291 PolarHBondContact O-N 3.45Å; M289-V292 PolarHBondContact O-N 2.9Å; M289-D293 WeakPolarHBondContact O-CB 3.3Å; M289-D293 PolarHBondContact O-N 2.85Å; M289-A344 WeakPolarHBondContact CA-O 3.48Å; M289-A344 HydrophobicContact CB-CB 4.39Å; M289-F347 HydrophobicContact CE-CD1 3.27Å; M289-F347 HydrophobicContact CE-CE1 3.38Å; M289-F347 HydrophobicContact CE-CG 4.27Å; M289-F347 HydrophobicContact CE-CZ 4.43Å; M289-F347 HydrophobicContact CG-CD1 4.43Å; M289-F347 HydrophobicContact SD-CD1 3.87Å; M289-F347 HydrophobicContact SD-CE1 3.86Å; M289-F347 HydrophobicContact SD-CG 4.44Å; M289-F347 HydrophobicContact SD-CZ 4.42Å; M289-G348 VanDerWaalsContact CG-CA 3.5Å
290	A	95.1	Very high	93.3	Very high	1 Å²	1	37.3 Å²	37.3	1%	0.008	19%	0.189	C	C	.	.	H	α-helix	trans	-64.5	-39.2	-179.7	0	0	0	0	0	112.3	P155 L158 L286 S287 I288 D293 M294	P155-A290 HydrophobicContact CB-CB 4.33Å; P155-A290 WeakPolarHBondContact CB-O 3.5Å; P155-A290 WeakPolarHBondContact O-CB 3.25Å; L158-A290 HydrophobicContact CB-CB 3.93Å; L158-A290 HydrophobicContact CD2-CB 3.94Å; L158-A290 HydrophobicContact CG-CB 3.91Å; L286-A290 VanDerWaalsContact O-CB 3.29Å; L286-A290 WeakPolarHBondContact O-CB 3.1Å; L286-A290 PolarHBondContact O-N 2.63Å; S287-A290 PolarHBondContact O-N 2.88Å; I288-A290 VanDerWaalsContact C-N 3.33Å; I288-A290 PolarHBondContact O-N 3.33Å; A290-D293 WeakPolarHBondContact O-CB 3.43Å; A290-D293 PolarHBondContact O-N 3.33Å; A290-M294 PolarHBondContact O-N 3.19Å
291	F	94.9	Very high	93	Very high	117 Å²	117	34 Å²	34	51%	0.513	18%	0.18	S	C	.	.	H	α-helix	trans	-63.2	-45.1	175.8	-171.1	-98.3	0	0	0	111.2	S287 I288 M289 M294 F295	S287-F291 WeakPolarHBondContact O-CB 3.16Å; S287-F291 PolarHBondContact O-N 3.07Å; I288-F291 PolarHBondContact O-N 2.99Å; M289-F291 PolarHBondContact O-N 3.45Å; F291-M294 VanDerWaalsContact O-CB 3.23Å; F291-M294 WeakPolarHBondContact O-CB 3.34Å; F291-M294 PolarHBondContact O-N 3.37Å; F291-F295 HydrophobicContact CD1-CD2 4.27Å; F291-F295 HydrophobicContact CD1-CE2 4.01Å; F291-F295 HydrophobicContact CD2-CE2 4.18Å; F291-F295 HydrophobicContact CE1-CD2 4.08Å; F291-F295 AromaticContact CE1-CE2 3.53Å; F291-F295 HydrophobicContact CE1-CE2 3.53Å; F291-F295 HydrophobicContact CE1-CZ 4.48Å; F291-F295 AromaticContact CE2-CE2 3.73Å; F291-F295 HydrophobicContact CE2-CE2 3.73Å; F291-F295 HydrophobicContact CE2-CZ 4.38Å; F291-F295 HydrophobicContact CG-CE2 4.33Å; F291-F295 HydrophobicContact CZ-CD2 4.37Å; F291-F295 AromaticContact CZ-CE2 3.39Å; F291-F295 HydrophobicContact CZ-CE2 3.39Å; F291-F295 HydrophobicContact CZ-CZ 4.03Å; F291-F295 VanDerWaalsContact O-CD2 3.25Å; F291-F295 WeakPolarHBondContact O-CD2 3.27Å
292	V	96.3	Very high	92.8	Very high	32 Å²	32	39.3 Å²	39.3	19%	0.194	21%	0.205	C	C	.	.	H	α-helix	trans	-64	-43.6	175.8	177.4	0	0	0	0	111.3	I288 M289 M294 F295 A296 I345 L349	I288-V292 WeakPolarHBondContact O-CG2 3.48Å; I288-V292 PolarHBondContact O-N 3.37Å; M289-V292 PolarHBondContact O-N 2.9Å; V292-M294 VanDerWaalsContact C-N 3.25Å; V292-M294 PolarHBondContact O-N 2.93Å; V292-F295 PolarHBondContact O-N 3.06Å; V292-A296 VanDerWaalsContact O-CB 3.25Å; V292-A296 WeakPolarHBondContact O-CB 3.41Å; V292-A296 PolarHBondContact O-N 2.88Å; V292-I345 HydrophobicContact CG1-CG2 4.47Å; V292-I345 WeakPolarHBondContact CG1-O 3.44Å; V292-I345 HydrophobicContact CG2-CB 4.34Å; V292-I345 HydrophobicContact CG2-CG1 4.14Å; V292-I345 HydrophobicContact CG2-CG2 4.16Å; V292-L349 HydrophobicContact CG1-CB 4.17Å
293	D	93.7	Very high	92.7	Very high	7 Å²	7	43.2 Å²	43.2	4%	0.037	23%	0.225	C	C	.	.	H	α-helix	trans	-55.6	-40	175	179	30.8	0	0	0	112	P155 M289 A290 F295 A296 R297 G352	P155-D293 HydrophobicContact CB-CB 4.48Å; M289-D293 WeakPolarHBondContact O-CB 3.3Å; M289-D293 PolarHBondContact O-N 2.85Å; A290-D293 WeakPolarHBondContact O-CB 3.43Å; A290-D293 PolarHBondContact O-N 3.33Å; D293-F295 VanDerWaalsContact C-N 3.31Å; D293-F295 PolarHBondContact O-N 2.63Å; D293-A296 PolarHBondContact O-N 3.22Å; D293-R297 VanDerWaalsContact CG-NE 3.28Å; D293-R297 WeakPolarHBondContact O-CG 3.38Å; D293-R297 PolarHBondContact O-N 3.32Å; D293-R297 WeakPolarHBondContact OD1-CD 3.1Å; D293-R297 VanDerWaalsContact OD1-CG 3.26Å; D293-R297 WeakPolarHBondContact OD1-CG 3.35Å; D293-R297 IonicContact OD1-CZ 2.74Å; D293-R297 IonicContact OD1-NE 3.67Å; D293-R297 PolarHBondContact OD1-NE 3.46Å; D293-R297 IonicContact OD1-NH2 2.69Å; D293-R297 IonicContact OD2-CZ 3.11Å; D293-R297 VanDerWaalsContact OD2-CZ 3.28Å; D293-R297 IonicContact OD2-NE 2.97Å; D293-R297 PolarHBondContact OD2-NE 2.95Å; D293-R297 VanDerWaalsContact OD2-NE 3.11Å; D293-R297 IonicContact OD2-NH2 3.28Å; D293-R297 PolarHBondContact OD2-NH2 3.08Å; D293-G352 WeakPolarHBondContact OD1-CA 3.28Å; D293-G352 PolarHBondContact OD1-N 3.34Å
294	M	91.1	Very high	92.5	Very high	58 Å²	58	43.2 Å²	43.2	29%	0.286	23%	0.225	S	C	.	.	H	α-helix	trans	-55.7	-42.3	177.2	-167.2	178.6	-174.9	0	0	113.1	P155 V156 A290 F291 V292 P298	P155-M294 HydrophobicContact CB-CB 3.98Å; P155-M294 HydrophobicContact CG-CB 3.98Å; P155-M294 HydrophobicContact CG-CG 4.2Å; V156-M294 HydrophobicContact CG2-CE 3.08Å; V156-M294 HydrophobicContact CG2-CG 4.47Å; V156-M294 HydrophobicContact CG2-SD 3.55Å; V156-M294 VanDerWaalsContact CG2-SD 3.55Å; A290-M294 PolarHBondContact O-N 3.19Å; F291-M294 VanDerWaalsContact O-CB 3.23Å; F291-M294 WeakPolarHBondContact O-CB 3.34Å; F291-M294 PolarHBondContact O-N 3.37Å; V292-M294 VanDerWaalsContact C-N 3.25Å; V292-M294 PolarHBondContact O-N 2.93Å; M294-P298 WeakPolarHBondContact O-CD 3.43Å
295	F	91.7	Very high	92	Very high	119 Å²	119	42 Å²	42	52%	0.522	22%	0.223	S	C	.	.	H	α-helix	trans	-88	-30.2	178.3	-65.9	-79.7	0	0	0	112.7	F291 V292 D293 S299	F291-F295 HydrophobicContact CD1-CD2 4.27Å; F291-F295 HydrophobicContact CD1-CE2 4.01Å; F291-F295 HydrophobicContact CD2-CE2 4.18Å; F291-F295 HydrophobicContact CE1-CD2 4.08Å; F291-F295 AromaticContact CE1-CE2 3.53Å; F291-F295 HydrophobicContact CE1-CE2 3.53Å; F291-F295 HydrophobicContact CE1-CZ 4.48Å; F291-F295 AromaticContact CE2-CE2 3.73Å; F291-F295 HydrophobicContact CE2-CE2 3.73Å; F291-F295 HydrophobicContact CE2-CZ 4.38Å; F291-F295 HydrophobicContact CG-CE2 4.33Å; F291-F295 HydrophobicContact CZ-CD2 4.37Å; F291-F295 AromaticContact CZ-CE2 3.39Å; F291-F295 HydrophobicContact CZ-CE2 3.39Å; F291-F295 HydrophobicContact CZ-CZ 4.03Å; F291-F295 VanDerWaalsContact O-CD2 3.25Å; F291-F295 WeakPolarHBondContact O-CD2 3.27Å; V292-F295 PolarHBondContact O-N 3.06Å; D293-F295 VanDerWaalsContact C-N 3.31Å; D293-F295 PolarHBondContact O-N 2.63Å; F295-S299 WeakPolarHBondContact O-CB 3.11Å; F295-S299 PolarHBondContact O-N 3.2Å; F295-S299 PolarHBondContact O-OG 3.18Å
296	A	92.3	Very high	91.7	Very high	6 Å²	6	44.4 Å²	44.4	5%	0.05	24%	0.24	C	C	.	.	H	α-helix	trans	-63.5	-44.1	177.9	0	0	0	0	0	111.3	V292 D293 S299 V300 L349	V292-A296 VanDerWaalsContact O-CB 3.25Å; V292-A296 WeakPolarHBondContact O-CB 3.41Å; V292-A296 PolarHBondContact O-N 2.88Å; D293-A296 PolarHBondContact O-N 3.22Å; A296-S299 PolarHBondContact O-N 2.98Å; A296-V300 VanDerWaalsContact O-CB 3.32Å; A296-V300 WeakPolarHBondContact O-CB 3.2Å; A296-V300 VanDerWaalsContact O-CG2 3.23Å; A296-V300 WeakPolarHBondContact O-CG2 3.28Å; A296-V300 PolarHBondContact O-N 2.88Å; A296-L349 HydrophobicContact CB-CD1 3.79Å
297	R	88.9	Confident	91.2	Very high	34 Å²	34	53.2 Å²	53.2	13%	0.128	28%	0.278	C	S	.	.	H	α-helix	trans	-59.3	-54.6	-174.1	-71.5	176.1	-168.9	-155.4	10.1	113.9	D293 S299 G301 S356	D293-R297 VanDerWaalsContact CG-NE 3.28Å; D293-R297 WeakPolarHBondContact O-CG 3.38Å; D293-R297 PolarHBondContact O-N 3.32Å; D293-R297 WeakPolarHBondContact OD1-CD 3.1Å; D293-R297 VanDerWaalsContact OD1-CG 3.26Å; D293-R297 WeakPolarHBondContact OD1-CG 3.35Å; D293-R297 IonicContact OD1-CZ 2.74Å; D293-R297 IonicContact OD1-NE 3.67Å; D293-R297 PolarHBondContact OD1-NE 3.46Å; D293-R297 IonicContact OD1-NH2 2.69Å; D293-R297 IonicContact OD2-CZ 3.11Å; D293-R297 VanDerWaalsContact OD2-CZ 3.28Å; D293-R297 IonicContact OD2-NE 2.97Å; D293-R297 PolarHBondContact OD2-NE 2.95Å; D293-R297 VanDerWaalsContact OD2-NE 3.11Å; D293-R297 IonicContact OD2-NH2 3.28Å; D293-R297 PolarHBondContact OD2-NH2 3.08Å; R297-S299 VanDerWaalsContact C-N 3.33Å; R297-S299 PolarHBondContact O-N 2.77Å; R297-G301 PolarHBondContact O-N 3.28Å; R297-S356 WeakPolarHBondContact CA-OG 3.16Å; R297-S356 VanDerWaalsContact CB-OG 3.25Å; R297-S356 WeakPolarHBondContact CB-OG 3.31Å; R297-S356 WeakPolarHBondContact CG-OG 3.05Å; R297-S356 PolarHBondContact O-OG 3.09Å
298	P	88.4	Confident	90.9	Very high	75 Å²	75	60.1 Å²	60.1	49%	0.487	31%	0.309	S	S	.	.	H	α-helix	trans	-63.8	-41.4	178.8	-20.3	34.1	0	0	0	111.6	M294 G301 L302	M294-P298 WeakPolarHBondContact O-CD 3.43Å; P298-G301 PolarHBondContact O-N 3.13Å; P298-L302 WeakPolarHBondContact O-CG 3.33Å; P298-L302 PolarHBondContact O-N 3.44Å
299	S	90.7	Very high	90.6	Very high	63 Å²	63	60 Å²	60	44%	0.441	31%	0.308	S	S	.	.	H	α-helix	trans	-60.5	-49.2	-178.9	-56.4	0	0	0	0	111.6	F295 A296 R297 L302 I303	F295-S299 WeakPolarHBondContact O-CB 3.11Å; F295-S299 PolarHBondContact O-N 3.2Å; F295-S299 PolarHBondContact O-OG 3.18Å; A296-S299 PolarHBondContact O-N 2.98Å; R297-S299 VanDerWaalsContact C-N 3.33Å; R297-S299 PolarHBondContact O-N 2.77Å; S299-L302 PolarHBondContact O-N 3.15Å; S299-I303 VanDerWaalsContact O-CG1 3.28Å; S299-I303 WeakPolarHBondContact O-CG1 3.38Å; S299-I303 PolarHBondContact O-N 3.48Å
300	V	91.8	Very high	90.2	Very high	11 Å²	11	62.4 Å²	62.4	7%	0.067	32%	0.317	C	S	.	.	H	α-helix	trans	-69.7	-36.3	179.3	175.2	0	0	0	0	111.5	A296 L302 I303 A304 F316 S353 V357	A296-V300 VanDerWaalsContact O-CB 3.32Å; A296-V300 WeakPolarHBondContact O-CB 3.2Å; A296-V300 VanDerWaalsContact O-CG2 3.23Å; A296-V300 WeakPolarHBondContact O-CG2 3.28Å; A296-V300 PolarHBondContact O-N 2.88Å; V300-L302 VanDerWaalsContact C-N 3.34Å; V300-L302 PolarHBondContact O-N 3.36Å; V300-I303 PolarHBondContact O-N 3.41Å; V300-A304 WeakPolarHBondContact O-CB 3.43Å; V300-A304 PolarHBondContact O-N 3.2Å; V300-F316 HydrophobicContact CG1-CE1 3.65Å; V300-F316 HydrophobicContact CG1-CZ 3.74Å; V300-S353 WeakPolarHBondContact CG2-OG 3.47Å; V300-V357 HydrophobicContact CG1-CG2 3.96Å
301	G	87.1	Confident	89.8	Confident	11 Å²	11	66.4 Å²	66.4	11%	0.113	34%	0.343	C	S	.	.	H	α-helix	trans	-60.6	-40.3	172.3	0	0	0	0	0	113	R297 P298 A304 N305	R297-G301 PolarHBondContact O-N 3.28Å; P298-G301 PolarHBondContact O-N 3.13Å; G301-A304 PolarHBondContact O-N 3.48Å; G301-N305 PolarHBondContact O-N 3.45Å; G301-N305 PolarHBondContact O-ND2 3.33Å
302	L	87.8	Confident	89.6	Confident	135 Å²	135	69 Å²	69	71%	0.707	35%	0.349	S	S	*	.	H	α-helix	trans	-65.6	-43.2	174.3	-70.7	172.3	0	0	0	111.5	P298 S299 V300 N305 S306	P298-L302 WeakPolarHBondContact O-CG 3.33Å; P298-L302 PolarHBondContact O-N 3.44Å; S299-L302 PolarHBondContact O-N 3.15Å; V300-L302 VanDerWaalsContact C-N 3.34Å; V300-L302 PolarHBondContact O-N 3.36Å; L302-N305 PolarHBondContact O-N 2.92Å; L302-S306 PolarHBondContact O-N 3.43Å
303	I	91.3	Very high	89.4	Confident	82 Å²	82	67.5 Å²	67.5	42%	0.421	34%	0.34	S	S	.	.	H	α-helix	trans	-59.7	-47.4	175.8	-67.8	165.8	0	0	0	110.5	S299 V300 N305 S306 I309 F316	S299-I303 VanDerWaalsContact O-CG1 3.28Å; S299-I303 WeakPolarHBondContact O-CG1 3.38Å; S299-I303 PolarHBondContact O-N 3.48Å; V300-I303 PolarHBondContact O-N 3.41Å; I303-N305 PolarHBondContact O-N 3.05Å; I303-S306 WeakPolarHBondContact O-CB 3.35Å; I303-S306 PolarHBondContact O-N 3.29Å; I303-I309 HydrophobicContact CG2-CD1 3.32Å; I303-I309 WeakPolarHBondContact O-CD1 3.41Å; I303-F316 HydrophobicContact CG2-CE2 4.33Å; I303-F316 HydrophobicContact CG2-CZ 4.04Å
304	A	88.4	Confident	89.3	Confident	0 Å²	0	67.6 Å²	67.6	0%	0	34%	0.341	C	S	.	.	H	α-helix	trans	-60.5	-28.5	179.1	0	0	0	0	0	113.3	V300 G301 R310 I313 F316 V357	V300-A304 WeakPolarHBondContact O-CB 3.43Å; V300-A304 PolarHBondContact O-N 3.2Å; G301-A304 PolarHBondContact O-N 3.48Å; A304-R310 WeakPolarHBondContact O-CA 3.47Å; A304-R310 PolarHBondContact O-N 3.47Å; A304-I313 HydrophobicContact CB-CD1 4.22Å; A304-F316 HydrophobicContact CB-CD1 4.13Å; A304-F316 HydrophobicContact CB-CE1 3.99Å; A304-V357 HydrophobicContact CB-CG2 4.2Å
305	N	85.3	Confident	89.5	Confident	70 Å²	70	68.2 Å²	68.2	37%	0.374	34%	0.34	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.9	-3.1	178.5	-78.4	-62.5	0	0	0	114.4	G301 L302 I303 R310 E360	G301-N305 PolarHBondContact O-N 3.45Å; G301-N305 PolarHBondContact O-ND2 3.33Å; L302-N305 PolarHBondContact O-N 2.92Å; I303-N305 PolarHBondContact O-N 3.05Å; N305-R310 PolarHBondContact OD1-NH1 3.45Å; N305-E360 PolarHBondContact ND2-OE1 3.05Å; N305-E360 PolarHBondContact ND2-OE2 3.05Å
306	S	88.2	Confident	89.6	Confident	50 Å²	50	64.6 Å²	64.6	35%	0.35	32%	0.324	S	S	.	.	S	Bend	trans	-63.4	148.4	175.3	-179.9	0	0	0	0	112.3	L302 I303 H308 I309 R310	L302-S306 PolarHBondContact O-N 3.43Å; I303-S306 WeakPolarHBondContact O-CB 3.35Å; I303-S306 PolarHBondContact O-N 3.29Å; S306-H308 PolarHBondContact O-N 3.25Å; S306-H308 VanDerWaalsContact O-N 3.07Å; S306-I309 PolarHBondContact O-N 3.35Å; S306-I309 VanDerWaalsContact O-N 3.1Å; S306-R310 WeakPolarHBondContact O-CB 3.27Å; S306-R310 PolarHBondContact O-N 3.47Å
307	K	85	Confident	89.8	Confident	184 Å²	184	64.3 Å²	64.3	80%	0.8	32%	0.322	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.4	-31	-177.6	-172.3	178.5	179.1	-177.5	0	113.4	P311	K307-P311 VanDerWaalsContact O-CD 3.25Å; K307-P311 WeakPolarHBondContact O-CD 3.16Å
308	H	88.3	Confident	90.1	Very high	157 Å²	157	62.7 Å²	62.7	73%	0.727	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.5	-33.4	-178.4	-61.3	-72.2	0	0	0	113.2	S306	S306-H308 PolarHBondContact O-N 3.25Å; S306-H308 VanDerWaalsContact O-N 3.07Å
309	I	90.1	Very high	90.5	Very high	46 Å²	46	65.5 Å²	65.5	24%	0.236	32%	0.321	C	S	.	.	T	Hydrogen-bonded Turn	trans	-93	-37.4	-172.8	-62	175	0	0	0	110.7	I303 S306 P311 R312 I313 F316	I303-I309 HydrophobicContact CG2-CD1 3.32Å; I303-I309 WeakPolarHBondContact O-CD1 3.41Å; S306-I309 PolarHBondContact O-N 3.35Å; S306-I309 VanDerWaalsContact O-N 3.1Å; I309-P311 VanDerWaalsContact C-CD 3.48Å; I309-R312 CarbonylContact O-C 3.56Å; I309-R312 WeakPolarHBondContact O-CA 3.43Å; I309-R312 PolarHBondContact O-N 3.46Å; I309-I313 PolarHBondContact O-N 3.04Å; I309-F316 HydrophobicContact CG2-CB 3.83Å; I309-F316 HydrophobicContact CG2-CD1 4.14Å; I309-F316 HydrophobicContact CG2-CD2 4.22Å; I309-F316 HydrophobicContact CG2-CG 3.8Å
310	R	87.6	Confident	90.8	Very high	52 Å²	52	62.8 Å²	62.8	20%	0.196	30%	0.302	C	S	.	.	G	3₁₀ helix	trans	-52	-44.9	-176.8	-172.8	71.7	-171	-170	17.6	114.1	A304 N305 S306 R312 I313 E360 D364	A304-R310 WeakPolarHBondContact O-CA 3.47Å; A304-R310 PolarHBondContact O-N 3.47Å; N305-R310 PolarHBondContact OD1-NH1 3.45Å; S306-R310 WeakPolarHBondContact O-CB 3.27Å; S306-R310 PolarHBondContact O-N 3.47Å; R310-R312 PolarHBondContact O-N 3.46Å; R310-R312 VanDerWaalsContact O-N 3.14Å; R310-I313 PolarHBondContact O-N 3.28Å; R310-E360 IonicContact NH1-OE2 3.95Å; R310-E360 PolarHBondContact NH1-OE2 3.22Å; R310-D364 IonicContact NH2-OD1 3.64Å
311	P	87.6	Confident	91	Very high	85 Å²	85	62.2 Å²	62.2	55%	0.552	30%	0.298	S	S	*	.	G	3₁₀ helix	trans	-65	-17.2	178.4	-20.8	34.2	0	0	0	114.1	K307 I309 Y429	K307-P311 VanDerWaalsContact O-CD 3.25Å; K307-P311 WeakPolarHBondContact O-CD 3.16Å; I309-P311 VanDerWaalsContact C-CD 3.48Å; P311-Y429 PolarHBondContact O-OH 2.98Å
312	R	90.4	Very high	91.6	Very high	172 Å²	172	63.9 Å²	63.9	65%	0.649	30%	0.304	S	S	*	.	G	3₁₀ helix	trans	-126	26.8	-175.2	-70.3	-168.4	-175.6	-176.3	3.6	111.8	I309 R310 Q314 Y315 F316	I309-R312 CarbonylContact O-C 3.56Å; I309-R312 WeakPolarHBondContact O-CA 3.43Å; I309-R312 PolarHBondContact O-N 3.46Å; R310-R312 PolarHBondContact O-N 3.46Å; R310-R312 VanDerWaalsContact O-N 3.14Å; R312-Q314 PolarHBondContact O-N 2.92Å; R312-Q314 VanDerWaalsContact O-N 3.09Å; R312-Y315 HydrophobicContact CB-CD2 4.01Å; R312-Y315 HydrophobicContact CG-CD2 4.24Å; R312-Y315 PolarHBondContact O-N 3.2Å; R312-F316 PolarHBondContact O-N 2.87Å
313	I	90.9	Very high	92	Very high	0 Å²	0	60.3 Å²	60.3	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-56.7	-30.9	-175.3	-167.2	168.6	0	0	0	112.7	A304 I309 R310 Y315 F316 F317 V357 E360 D364	A304-I313 HydrophobicContact CB-CD1 4.22Å; I309-I313 PolarHBondContact O-N 3.04Å; R310-I313 PolarHBondContact O-N 3.28Å; I313-Y315 VanDerWaalsContact C-N 3.33Å; I313-Y315 PolarHBondContact O-N 3.26Å; I313-F316 WeakPolarHBondContact O-CB 3.34Å; I313-F316 PolarHBondContact O-N 2.93Å; I313-F317 PolarHBondContact O-N 3.45Å; I313-V357 HydrophobicContact CD1-CG1 4.31Å; I313-V357 HydrophobicContact CG1-CG1 3.88Å; I313-E360 HydrophobicContact CD1-CB 3.77Å; I313-D364 HydrophobicContact CG2-CB 4.13Å
314	Q	92.8	Very high	92.3	Very high	10 Å²	10	56.4 Å²	56.4	5%	0.047	26%	0.263	C	S	.	.	H	α-helix	trans	-64.6	-34.7	178.5	-65.4	147	24.4	0	0	112.5	R312 S318 T361 D364 L365 N425 Y429	R312-Q314 PolarHBondContact O-N 2.92Å; R312-Q314 VanDerWaalsContact O-N 3.09Å; Q314-S318 PolarHBondContact O-N 3.29Å; Q314-S318 PolarHBondContact O-OG 3.3Å; Q314-S318 VanDerWaalsContact O-OG 3.1Å; Q314-T361 HydrophobicContact CB-CG2 4.41Å; Q314-T361 HydrophobicContact CG-CG2 3.74Å; Q314-D364 PolarHBondContact NE2-OD2 2.89Å; Q314-L365 HydrophobicContact CG-CD2 4.32Å; Q314-L365 HydrophobicContact CG-CG 4.43Å; Q314-N425 PolarHBondContact O-ND2 2.91Å; Q314-Y429 HydrophobicContact CB-CE2 4.26Å; Q314-Y429 PolarHBondContact OE1-OH 3.27Å
315	Y	94.4	Very high	92.7	Very high	71 Å²	71	56.4 Å²	56.4	28%	0.278	26%	0.263	S	S	.	.	H	α-helix	trans	-74	-38.4	173	-67.3	-65.6	0	0	0	111.8	R312 I313 F317 S318 F319 L422 N425 A426 Y429	R312-Y315 HydrophobicContact CB-CD2 4.01Å; R312-Y315 HydrophobicContact CG-CD2 4.24Å; R312-Y315 PolarHBondContact O-N 3.2Å; I313-Y315 VanDerWaalsContact C-N 3.33Å; I313-Y315 PolarHBondContact O-N 3.26Å; Y315-F317 VanDerWaalsContact C-N 3.29Å; Y315-F317 PolarHBondContact O-N 2.94Å; Y315-S318 PolarHBondContact O-N 3.43Å; Y315-F319 PolarHBondContact O-N 3.04Å; Y315-L422 HydrophobicContact CD1-CD2 3.98Å; Y315-N425 HydrophobicContact CE1-CB 4.36Å; Y315-A426 HydrophobicContact CE1-CB 4.38Å; Y315-A426 WeakPolarHBondContact OH-CA 3.2Å; Y315-Y429 HydrophobicContact CD2-CD2 4.33Å; Y315-Y429 AromaticContact CD2-CE2 3.82Å; Y315-Y429 HydrophobicContact CD2-CE2 3.82Å; Y315-Y429 HydrophobicContact CE1-CD2 4.47Å; Y315-Y429 AromaticContact CE2-CD2 3.39Å; Y315-Y429 HydrophobicContact CE2-CD2 3.39Å; Y315-Y429 AromaticContact CE2-CE2 3.3Å; Y315-Y429 HydrophobicContact CE2-CE2 3.3Å; Y315-Y429 HydrophobicContact CE2-CG 4.32Å; Y315-Y429 AromaticContact CZ-CD2 3.48Å; Y315-Y429 VanDerWaalsContact CZ-CD2 3.48Å; Y315-Y429 AromaticContact CZ-CE2 3.8Å; Y315-Y429 VanDerWaalsContact OH-CD2 3.32Å; Y315-Y429 WeakPolarHBondContact OH-CD2 3.33Å
316	F	95.2	Very high	93.3	Very high	42 Å²	42	56 Å²	56	18%	0.184	26%	0.262	C	S	.	.	H	α-helix	trans	-61.3	-40.5	175	-177.5	-113.6	0	0	0	111.4	V300 I303 A304 I309 R312 I313 F319 A320 V357	V300-F316 HydrophobicContact CG1-CE1 3.65Å; V300-F316 HydrophobicContact CG1-CZ 3.74Å; I303-F316 HydrophobicContact CG2-CE2 4.33Å; I303-F316 HydrophobicContact CG2-CZ 4.04Å; A304-F316 HydrophobicContact CB-CD1 4.13Å; A304-F316 HydrophobicContact CB-CE1 3.99Å; I309-F316 HydrophobicContact CG2-CB 3.83Å; I309-F316 HydrophobicContact CG2-CD1 4.14Å; I309-F316 HydrophobicContact CG2-CD2 4.22Å; I309-F316 HydrophobicContact CG2-CG 3.8Å; R312-F316 PolarHBondContact O-N 2.87Å; I313-F316 WeakPolarHBondContact O-CB 3.34Å; I313-F316 PolarHBondContact O-N 2.93Å; F316-F319 PolarHBondContact O-N 3.2Å; F316-A320 PolarHBondContact O-N 3.26Å; F316-V357 HydrophobicContact CD1-CG1 4.2Å; F316-V357 HydrophobicContact CD1-CG2 3.84Å; F316-V357 HydrophobicContact CE1-CG2 3.64Å
317	F	95.4	Very high	93.7	Very high	1 Å²	1	54.1 Å²	54.1	0%	0.004	25%	0.249	C	C	.	.	H	α-helix	trans	-58.5	-49.5	172.4	-176.7	-123.9	0	0	0	112	Y250 I313 Y315 F319 A320 I321 V354 V357 L358 T361 L421	Y250-F317 HydrophobicContact CD2-CE1 4.38Å; Y250-F317 AromaticContact CE2-CE1 3.99Å; Y250-F317 HydrophobicContact CE2-CE1 3.99Å; Y250-F317 HydrophobicContact CE2-CZ 4.41Å; I313-F317 PolarHBondContact O-N 3.45Å; Y315-F317 VanDerWaalsContact C-N 3.29Å; Y315-F317 PolarHBondContact O-N 2.94Å; F317-F319 VanDerWaalsContact C-N 3.3Å; F317-F319 PolarHBondContact O-N 3.14Å; F317-A320 WeakPolarHBondContact O-CB 3.3Å; F317-A320 PolarHBondContact O-N 3.32Å; F317-I321 HydrophobicContact CD1-CD1 3.94Å; F317-I321 HydrophobicContact CD2-CD1 4.39Å; F317-I321 HydrophobicContact CE1-CD1 3.55Å; F317-I321 HydrophobicContact CE2-CD1 4.03Å; F317-I321 HydrophobicContact CE2-CG1 4.33Å; F317-I321 HydrophobicContact CG-CD1 4.35Å; F317-I321 HydrophobicContact CZ-CD1 3.6Å; F317-I321 HydrophobicContact CZ-CG1 4.34Å; F317-I321 WeakPolarHBondContact O-CG1 3.46Å; F317-I321 PolarHBondContact O-N 3.09Å; F317-V354 HydrophobicContact CE2-CG1 4.07Å; F317-V357 HydrophobicContact CB-CG1 3.74Å; F317-V357 HydrophobicContact CD2-CB 4.04Å; F317-V357 HydrophobicContact CD2-CG1 3.92Å; F317-V357 HydrophobicContact CG-CG1 4.24Å; F317-L358 HydrophobicContact CE2-CB 4.19Å; F317-L358 HydrophobicContact CE2-CD1 3.95Å; F317-L358 HydrophobicContact CZ-CD1 3.55Å; F317-T361 HydrophobicContact CB-CG2 4.49Å; F317-T361 HydrophobicContact CD1-CG2 4.34Å; F317-L421 HydrophobicContact CD1-CD1 4.32Å; F317-L421 HydrophobicContact CE1-CD1 3.98Å
318	S	96.3	Very high	94.2	Very high	0 Å²	0	45.4 Å²	45.4	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-64	-35.1	178.2	-50.3	0	0	0	0	112.9	Q314 Y315 I321 M322 L421 L422	Q314-S318 PolarHBondContact O-N 3.29Å; Q314-S318 PolarHBondContact O-OG 3.3Å; Q314-S318 VanDerWaalsContact O-OG 3.1Å; Y315-S318 PolarHBondContact O-N 3.43Å; S318-I321 PolarHBondContact O-N 3.1Å; S318-M322 WeakPolarHBondContact O-CB 3.34Å; S318-M322 PolarHBondContact O-N 3.35Å; S318-L421 WeakPolarHBondContact OG-CB 3.4Å; S318-L422 VanDerWaalsContact CB-CD2 3.43Å
319	F	96.2	Very high	94.6	Very high	134 Å²	134	41.1 Å²	41.1	59%	0.588	19%	0.194	S	C	*	.	H	α-helix	trans	-64.4	-42	173.2	177.5	-98.2	0	0	0	112.1	Y315 F316 F317 I321 M322 F323	Y315-F319 PolarHBondContact O-N 3.04Å; F316-F319 PolarHBondContact O-N 3.2Å; F317-F319 VanDerWaalsContact C-N 3.3Å; F317-F319 PolarHBondContact O-N 3.14Å; F319-I321 VanDerWaalsContact C-N 3.32Å; F319-I321 PolarHBondContact O-N 3.38Å; F319-M322 WeakPolarHBondContact O-CB 3.43Å; F319-M322 PolarHBondContact O-N 2.94Å; F319-F323 WeakPolarHBondContact O-CB 3.37Å; F319-F323 PolarHBondContact O-N 3.45Å
320	A	96.6	Very high	94.8	Very high	5 Å²	5	43.7 Å²	43.7	4%	0.041	21%	0.207	C	C	.	.	H	α-helix	trans	-61.5	-40.2	175.6	0	0	0	0	0	112.1	F316 F317 N324 V354	F316-A320 PolarHBondContact O-N 3.26Å; F317-A320 WeakPolarHBondContact O-CB 3.3Å; F317-A320 PolarHBondContact O-N 3.32Å; A320-N324 PolarHBondContact O-N 3.49Å; A320-N324 VanDerWaalsContact O-N 3.08Å; A320-V354 HydrophobicContact CB-CG2 4.07Å
321	I	97.4	Very high	95.1	Very high	0 Å²	0	41.2 Å²	41.2	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-66.3	-44.2	175.1	-60.7	168.6	0	0	0	110.7	M257 F317 S318 F319 F323 N324 G325 V354 V414 L421	M257-I321 HydrophobicContact CG-CG2 4.04Å; M257-I321 HydrophobicContact SD-CD1 3.61Å; M257-I321 HydrophobicContact SD-CG1 3.72Å; M257-I321 HydrophobicContact SD-CG2 4.07Å; F317-I321 HydrophobicContact CD1-CD1 3.94Å; F317-I321 HydrophobicContact CD2-CD1 4.39Å; F317-I321 HydrophobicContact CE1-CD1 3.55Å; F317-I321 HydrophobicContact CE2-CD1 4.03Å; F317-I321 HydrophobicContact CE2-CG1 4.33Å; F317-I321 HydrophobicContact CG-CD1 4.35Å; F317-I321 HydrophobicContact CZ-CD1 3.6Å; F317-I321 HydrophobicContact CZ-CG1 4.34Å; F317-I321 WeakPolarHBondContact O-CG1 3.46Å; F317-I321 PolarHBondContact O-N 3.09Å; S318-I321 PolarHBondContact O-N 3.1Å; F319-I321 VanDerWaalsContact C-N 3.32Å; F319-I321 PolarHBondContact O-N 3.38Å; I321-F323 PolarHBondContact O-N 3.22Å; I321-N324 PolarHBondContact O-N 3.47Å; I321-G325 PolarHBondContact O-N 2.93Å; I321-V354 HydrophobicContact CG1-CG1 4.38Å; I321-V354 HydrophobicContact CG1-CG2 3.94Å; I321-V414 HydrophobicContact CG2-CG1 3.63Å; I321-V414 WeakPolarHBondContact O-CG1 3.36Å; I321-L421 HydrophobicContact CD1-CD1 3.48Å; I321-L421 VanDerWaalsContact CD1-CD1 3.48Å
322	M	97.7	Very high	95.4	Very high	46 Å²	46	38.1 Å²	38.1	23%	0.227	18%	0.178	C	C	.	.	H	α-helix	trans	-57.9	-49.6	176.9	179.9	68.2	80.1	0	0	111	S318 F319 N324 G325 V326 V415 S418 V419 L422	S318-M322 WeakPolarHBondContact O-CB 3.34Å; S318-M322 PolarHBondContact O-N 3.35Å; F319-M322 WeakPolarHBondContact O-CB 3.43Å; F319-M322 PolarHBondContact O-N 2.94Å; M322-N324 VanDerWaalsContact C-N 3.3Å; M322-N324 PolarHBondContact O-N 3.43Å; M322-G325 PolarHBondContact O-N 3.21Å; M322-V326 HydrophobicContact CG-CG2 4.49Å; M322-V326 WeakPolarHBondContact O-CG2 3.42Å; M322-V326 PolarHBondContact O-N 2.95Å; M322-V326 HydrophobicContact SD-CG2 4.36Å; M322-V415 HydrophobicContact CE-CG1 4.35Å; M322-V415 HydrophobicContact SD-CB 4.36Å; M322-V415 HydrophobicContact SD-CG1 3.79Å; M322-V415 HydrophobicContact SD-CG2 4.09Å; M322-S418 WeakPolarHBondContact CE-OG 3.28Å; M322-S418 PolarHBondContact SD-OG 3.01Å; M322-S418 VanDerWaalsContact SD-OG 3.38Å; M322-V419 HydrophobicContact CE-CG2 3.68Å; M322-L422 HydrophobicContact CE-CD1 4.39Å
323	F	97.6	Very high	95.4	Very high	60 Å²	60	36.2 Å²	36.2	26%	0.263	18%	0.18	S	C	.	.	H	α-helix	trans	-55	-46.7	176.4	170.2	-100.6	0	0	0	111.3	F319 I321 V326 C327 F346 L349	F319-F323 WeakPolarHBondContact O-CB 3.37Å; F319-F323 PolarHBondContact O-N 3.45Å; I321-F323 PolarHBondContact O-N 3.22Å; F323-V326 PolarHBondContact O-N 2.94Å; F323-C327 PolarHBondContact O-N 2.96Å; F323-C327 PolarHBondContact O-SG 3.19Å; F323-F346 WeakPolarHBondContact CE1-O 3.47Å; F323-F346 HydrophobicContact CE2-CD1 4.44Å; F323-F346 HydrophobicContact CZ-CB 4.25Å; F323-F346 AromaticContact CZ-CD1 3.96Å; F323-F346 HydrophobicContact CZ-CD1 3.96Å; F323-L349 HydrophobicContact CE1-CB 4.39Å; F323-L349 HydrophobicContact CE1-CD2 4.31Å; F323-L349 HydrophobicContact CE1-CG 4.31Å; F323-L349 HydrophobicContact CZ-CD2 4.12Å
324	N	97.1	Very high	95.4	Very high	0 Å²	0	36.5 Å²	36.5	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-64.2	-42.6	178	-168.9	37.6	0	0	0	112.8	F261 A320 I321 M322 V326 C327 H328 F347	F261-N324 WeakPolarHBondContact CE2-ND2 3.22Å; A320-N324 PolarHBondContact O-N 3.49Å; A320-N324 VanDerWaalsContact O-N 3.08Å; I321-N324 PolarHBondContact O-N 3.47Å; M322-N324 VanDerWaalsContact C-N 3.3Å; M322-N324 PolarHBondContact O-N 3.43Å; N324-V326 PolarHBondContact O-N 3.11Å; N324-C327 WeakPolarHBondContact O-CB 3.43Å; N324-C327 PolarHBondContact O-N 2.79Å; N324-H328 PolarHBondContact ND2-NE2 3.43Å; N324-H328 PolarHBondContact O-CD2 2.94Å; N324-H328 PolarHBondContact O-N 3.13Å; N324-H328 VanDerWaalsContact O-N 3.08Å; N324-F347 WeakPolarHBondContact OD1-CD2 3.42Å
325	G	97.3	Very high	95	Very high	0 Å²	0	43 Å²	43	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-62.5	-41.9	177	0	0	0	0	0	112.8	I321 M322 H328 L329 G411	I321-G325 PolarHBondContact O-N 2.93Å; M322-G325 PolarHBondContact O-N 3.21Å; G325-H328 PolarHBondContact O-N 3.09Å; G325-L329 WeakPolarHBondContact O-CG 3.37Å; G325-L329 PolarHBondContact O-N 3.38Å; G325-G411 WeakPolarHBondContact O-CA 3.33Å
326	V	97.6	Very high	94.8	Very high	61 Å²	61	45 Å²	45	37%	0.37	23%	0.228	S	C	.	.	H	α-helix	trans	-63.7	-40.7	173.8	173.9	0	0	0	0	111	M322 F323 N324 H328 L329 L330 V415	M322-V326 HydrophobicContact CG-CG2 4.49Å; M322-V326 WeakPolarHBondContact O-CG2 3.42Å; M322-V326 PolarHBondContact O-N 2.95Å; M322-V326 HydrophobicContact SD-CG2 4.36Å; F323-V326 PolarHBondContact O-N 2.94Å; N324-V326 PolarHBondContact O-N 3.11Å; V326-H328 VanDerWaalsContact C-N 3.28Å; V326-H328 PolarHBondContact O-N 2.85Å; V326-L329 PolarHBondContact O-N 3.14Å; V326-L329 VanDerWaalsContact O-N 3.13Å; V326-L330 HydrophobicContact CG1-CD1 4.03Å; V326-L330 HydrophobicContact CG1-CG 4.38Å; V326-L330 WeakPolarHBondContact O-CG 3.41Å; V326-L330 PolarHBondContact O-N 3.36Å; V326-L330 VanDerWaalsContact O-N 3.08Å; V326-V415 HydrophobicContact CG2-CG2 4.28Å
327	C	96.6	Very high	94.7	Very high	11 Å²	11	46.7 Å²	46.7	7%	0.074	23%	0.234	C	C	.	.	H	α-helix	trans	-57.4	-41.7	174.3	-67.1	0	0	0	0	111.9	F323 N324 L330 C331 Y343	F323-C327 PolarHBondContact O-N 2.96Å; F323-C327 PolarHBondContact O-SG 3.19Å; N324-C327 WeakPolarHBondContact O-CB 3.43Å; N324-C327 PolarHBondContact O-N 2.79Å; C327-L330 PolarHBondContact O-N 3.46Å; C327-C331 PolarHBondContact O-N 2.89Å; C327-Y343 WeakPolarHBondContact O-CE2 3.44Å
328	H	96.2	Very high	94.7	Very high	0 Å²	0	51.5 Å²	51.5	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-65.3	-38.7	175.4	-65.6	-36.4	0	0	0	113.2	P264 N324 G325 V326 L330 C331 Y343 F347	P264-H328 WeakPolarHBondContact CB-CE1 3.42Å; N324-H328 PolarHBondContact ND2-NE2 3.43Å; N324-H328 PolarHBondContact O-CD2 2.94Å; N324-H328 PolarHBondContact O-N 3.13Å; N324-H328 VanDerWaalsContact O-N 3.08Å; G325-H328 PolarHBondContact O-N 3.09Å; V326-H328 VanDerWaalsContact C-N 3.28Å; V326-H328 PolarHBondContact O-N 2.85Å; H328-L330 PolarHBondContact O-N 2.84Å; H328-C331 WeakPolarHBondContact O-CB 3.28Å; H328-C331 PolarHBondContact O-N 2.85Å; H328-Y343 PolarHBondContact ND1-OH 3.22Å; H328-F347 AromaticContact CE1-CD2 3.51Å; H328-F347 AromaticContact CE1-CE2 3.27Å; H328-F347 WeakPolarHBondContact CE1-CE2 3.39Å; H328-F347 AromaticContact CE1-CZ 3.54Å; H328-F347 AromaticContact NE2-CE2 3.7Å
329	L	96.2	Very high	94.6	Very high	68 Å²	68	53 Å²	53	36%	0.356	27%	0.274	S	S	.	.	H	α-helix	trans	-65.2	-26.9	175.9	-69.7	176.3	0	0	0	113.1	G325 V326 P332 M408 V415	G325-L329 WeakPolarHBondContact O-CG 3.37Å; G325-L329 PolarHBondContact O-N 3.38Å; V326-L329 PolarHBondContact O-N 3.14Å; V326-L329 VanDerWaalsContact O-N 3.13Å; L329-P332 WeakPolarHBondContact O-CD 3.38Å; L329-M408 WeakPolarHBondContact CD2-O 3.38Å; L329-V415 HydrophobicContact CD1-CG2 4.05Å
330	L	94.3	Very high	94.6	Very high	99 Å²	99	46.7 Å²	46.7	52%	0.518	25%	0.246	S	C	.	.	H	α-helix	trans	-86.8	-16.7	178.5	-64.2	174.7	0	0	0	113.2	V326 C327 H328 P332 L333	V326-L330 HydrophobicContact CG1-CD1 4.03Å; V326-L330 HydrophobicContact CG1-CG 4.38Å; V326-L330 WeakPolarHBondContact O-CG 3.41Å; V326-L330 PolarHBondContact O-N 3.36Å; V326-L330 VanDerWaalsContact O-N 3.08Å; C327-L330 PolarHBondContact O-N 3.46Å; H328-L330 PolarHBondContact O-N 2.84Å; L330-P332 VanDerWaalsContact C-CD 3.42Å; L330-L333 HydrophobicContact CD2-CD1 4.01Å; L330-L333 WeakPolarHBondContact O-CB 3.45Å; L330-L333 PolarHBondContact O-N 3.36Å; L330-L333 VanDerWaalsContact O-N 3.12Å
331	C	94.1	Very high	94.6	Very high	1 Å²	1	47.9 Å²	47.9	1%	0.007	25%	0.253	C	S	.	.	G	3₁₀ helix	trans	-54.1	-40.6	179.1	-170.7	0	0	0	0	114.4	C327 H328 L333 A334 Y343 Y407	C327-C331 PolarHBondContact O-N 2.89Å; H328-C331 WeakPolarHBondContact O-CB 3.28Å; H328-C331 PolarHBondContact O-N 2.85Å; C331-L333 PolarHBondContact O-N 2.99Å; C331-A334 VanDerWaalsContact O-CB 3.26Å; C331-A334 WeakPolarHBondContact O-CB 3.44Å; C331-A334 PolarHBondContact O-N 3.15Å; C331-Y343 HydrophobicContact CB-CD2 3.77Å; C331-Y343 HydrophobicContact CB-CE2 3.57Å; C331-Y343 HydrophobicContact CB-CG 4.37Å; C331-Y407 HydrophobicContact CB-CD1 3.99Å; C331-Y407 HydrophobicContact CB-CE1 4.47Å; C331-Y407 HydrophobicContact CB-CG 4.08Å
332	P	92.9	Very high	94.6	Very high	19 Å²	19	52.4 Å²	52.4	12%	0.123	28%	0.277	C	S	.	.	G	3₁₀ helix	trans	-57.6	-20.4	177.5	-29.4	38.3	0	0	0	115.6	L329 L330 A334 K404 M408	L329-P332 WeakPolarHBondContact O-CD 3.38Å; L330-P332 VanDerWaalsContact C-CD 3.42Å; P332-A334 VanDerWaalsContact C-N 3.27Å; P332-K404 HydrophobicContact CB-CB 3.99Å; P332-K404 HydrophobicContact CB-CD 4.39Å; P332-K404 HydrophobicContact CB-CG 3.83Å; P332-K404 HydrophobicContact CG-CB 4.28Å; P332-M408 HydrophobicContact CG-CG 3.87Å
333	L	91.8	Very high	94.5	Very high	133 Å²	133	50.9 Å²	50.9	70%	0.696	27%	0.269	S	S	*	.	G	3₁₀ helix	trans	-78.3	-13.6	176.5	-63	167.9	0	0	0	112.2	L330 C331 Q335	L330-L333 HydrophobicContact CD2-CD1 4.01Å; L330-L333 WeakPolarHBondContact O-CB 3.45Å; L330-L333 PolarHBondContact O-N 3.36Å; L330-L333 VanDerWaalsContact O-N 3.12Å; C331-L333 PolarHBondContact O-N 2.99Å; L333-Q335 PolarHBondContact O-N 3.09Å
334	A	89.5	Confident	94.5	Very high	6 Å²	6	48 Å²	48	5%	0.05	26%	0.256	C	S	.	.			trans	-80.7	109.8	178.8	0	0	0	0	0	110.6	Q275 C331 P332 S339 L340	Q275-A334 PolarHBondContact NE2-O 3.41Å; C331-A334 VanDerWaalsContact O-CB 3.26Å; C331-A334 WeakPolarHBondContact O-CB 3.44Å; C331-A334 PolarHBondContact O-N 3.15Å; P332-A334 VanDerWaalsContact C-N 3.27Å; A334-S339 WeakPolarHBondContact CA-OG 3.05Å; A334-S339 VanDerWaalsContact CB-OG 3.3Å; A334-S339 WeakPolarHBondContact CB-OG 3.28Å; A334-L340 HydrophobicContact CB-CD2 3.84Å; A334-L340 HydrophobicContact CB-CG 4.11Å
335	Q	84.3	Confident	94.5	Very high	145 Å²	145	51 Å²	51	68%	0.678	27%	0.272	S	S	*	.			trans	-111	-22.9	179.6	-62.2	-175.8	1.3	0	0	112.7	L333 S339	L333-Q335 PolarHBondContact O-N 3.09Å; Q335-S339 PolarHBondContact N-OG 3.48Å; Q335-S339 VanDerWaalsContact N-OG 3.15Å
336	D	91.4	Very high	94.5	Very high	115 Å²	115	56.1 Å²	56.1	62%	0.615	29%	0.294	S	S	*	.	S	Bend	trans	-109.3	156.4	-179.1	-57.8	-52.6	0	0	0	111.5	T338 S339 L340	D336-T338 VanDerWaalsContact C-N 3.28Å; D336-T338 PolarHBondContact O-N 3.41Å; D336-S339 PolarHBondContact N-OG 3.05Å; D336-S339 PolarHBondContact O-N 3.27Å; D336-S339 PolarHBondContact O-OG 2.85Å; D336-L340 PolarHBondContact O-N 3.49Å; D336-L340 VanDerWaalsContact O-N 3.07Å
337	Y	93.3	Very high	94.5	Very high	77 Å²	77	53.2 Å²	53.2	30%	0.302	28%	0.276	S	S	.	.	H	α-helix	trans	-53	-44.1	176.9	-177	-112.4	0	0	0	112.8	I277 S281 L285 S339 L340 V341	I277-Y337 HydrophobicContact CD1-CD2 4.14Å; I277-Y337 HydrophobicContact CG2-CD2 3.83Å; I277-Y337 HydrophobicContact CG2-CE2 4.22Å; S281-Y337 PolarHBondContact O-OH 3.17Å; L285-Y337 HydrophobicContact CD2-CE2 3.89Å; L285-Y337 HydrophobicContact CG-CE2 4.07Å; Y337-S339 VanDerWaalsContact C-N 3.29Å; Y337-S339 PolarHBondContact O-N 3.1Å; Y337-L340 PolarHBondContact O-N 3.47Å; Y337-L340 VanDerWaalsContact O-N 3.13Å; Y337-V341 HydrophobicContact CD1-CG2 4.08Å; Y337-V341 HydrophobicContact CE1-CG2 3.68Å; Y337-V341 HydrophobicContact CE2-CG2 4.18Å; Y337-V341 WeakPolarHBondContact O-CG2 3.4Å; Y337-V341 PolarHBondContact O-N 2.92Å
338	T	94.8	Very high	94.5	Very high	101 Å²	101	52.7 Å²	52.7	62%	0.62	27%	0.273	S	S	*	.	H	α-helix	trans	-59	-40	177.6	-52.6	0	0	0	0	112.2	D336 V341 L342	D336-T338 VanDerWaalsContact C-N 3.28Å; D336-T338 PolarHBondContact O-N 3.41Å; T338-V341 PolarHBondContact O-N 3.27Å; T338-L342 WeakPolarHBondContact O-CG 3.1Å; T338-L342 PolarHBondContact O-N 2.96Å
339	S	94.9	Very high	94.5	Very high	33 Å²	33	55.8 Å²	55.8	23%	0.231	29%	0.289	C	S	.	.	H	α-helix	trans	-69.2	-35.1	177.9	67.4	0	0	0	0	112.2	A334 Q335 D336 Y337 L342 Y343	A334-S339 WeakPolarHBondContact CA-OG 3.05Å; A334-S339 VanDerWaalsContact CB-OG 3.3Å; A334-S339 WeakPolarHBondContact CB-OG 3.28Å; Q335-S339 PolarHBondContact N-OG 3.48Å; Q335-S339 VanDerWaalsContact N-OG 3.15Å; D336-S339 PolarHBondContact N-OG 3.05Å; D336-S339 PolarHBondContact O-N 3.27Å; D336-S339 PolarHBondContact O-OG 2.85Å; Y337-S339 VanDerWaalsContact C-N 3.29Å; Y337-S339 PolarHBondContact O-N 3.1Å; S339-L342 PolarHBondContact O-N 3.47Å; S339-Y343 PolarHBondContact O-N 3.22Å
340	L	95.2	Very high	94.5	Very high	0 Å²	0	52.5 Å²	52.5	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-69.8	-34.1	172	-75.2	174.4	0	0	0	113	Y271 A272 I277 L285 A334 D336 Y337 Y343 A344	Y271-L340 HydrophobicContact CD1-CD2 4.14Å; Y271-L340 HydrophobicContact CE1-CD2 3.81Å; A272-L340 HydrophobicContact CB-CD1 4.22Å; I277-L340 HydrophobicContact CD1-CD1 3.32Å; L285-L340 HydrophobicContact CD1-CB 4.06Å; L285-L340 HydrophobicContact CD1-CD1 4.22Å; L285-L340 HydrophobicContact CD2-CB 4.07Å; A334-L340 HydrophobicContact CB-CD2 3.84Å; A334-L340 HydrophobicContact CB-CG 4.11Å; D336-L340 PolarHBondContact O-N 3.49Å; D336-L340 VanDerWaalsContact O-N 3.07Å; Y337-L340 PolarHBondContact O-N 3.47Å; Y337-L340 VanDerWaalsContact O-N 3.13Å; L340-Y343 WeakPolarHBondContact O-CB 3.4Å; L340-Y343 PolarHBondContact O-N 3.38Å; L340-A344 WeakPolarHBondContact O-CB 3.35Å; L340-A344 PolarHBondContact O-N 3.38Å
341	V	96.9	Very high	94.5	Very high	31 Å²	31	48.4 Å²	48.4	19%	0.188	25%	0.25	C	C	.	.	H	α-helix	trans	-63.1	-45.8	171.9	169	0	0	0	0	110.4	L285 I288 Y337 T338 Y343 A344 I345	L285-V341 HydrophobicContact CD2-CB 4.47Å; L285-V341 HydrophobicContact CD2-CG2 3.76Å; I288-V341 HydrophobicContact CD1-CG1 4.14Å; I288-V341 HydrophobicContact CD1-CG2 4.02Å; Y337-V341 HydrophobicContact CD1-CG2 4.08Å; Y337-V341 HydrophobicContact CE1-CG2 3.68Å; Y337-V341 HydrophobicContact CE2-CG2 4.18Å; Y337-V341 WeakPolarHBondContact O-CG2 3.4Å; Y337-V341 PolarHBondContact O-N 2.92Å; T338-V341 PolarHBondContact O-N 3.27Å; V341-Y343 VanDerWaalsContact C-N 3.33Å; V341-Y343 PolarHBondContact O-N 3.4Å; V341-A344 PolarHBondContact O-N 2.9Å; V341-I345 HydrophobicContact CG1-CD1 4.16Å; V341-I345 WeakPolarHBondContact O-CG1 3.32Å; V341-I345 PolarHBondContact O-N 3.33Å
342	L	96.9	Very high	94.4	Very high	95 Å²	95	48.3 Å²	48.3	50%	0.497	25%	0.249	S	C	.	.	H	α-helix	trans	-60	-43.4	174.5	-72	174.3	0	0	0	111.7	T338 S339 I345 F346	T338-L342 WeakPolarHBondContact O-CG 3.1Å; T338-L342 PolarHBondContact O-N 2.96Å; S339-L342 PolarHBondContact O-N 3.47Å; L342-I345 PolarHBondContact O-N 3.49Å; L342-F346 VanDerWaalsContact O-CD2 3.22Å; L342-F346 WeakPolarHBondContact O-CD2 3.4Å; L342-F346 PolarHBondContact O-N 2.83Å; L342-F346 VanDerWaalsContact O-N 3.12Å
343	Y	96.7	Very high	94.5	Very high	14 Å²	14	48 Å²	48	6%	0.055	25%	0.248	C	C	.	.	H	α-helix	trans	-58.7	-46.7	172.7	166.5	-102.1	0	0	0	111.9	L268 C327 H328 C331 S339 L340 V341 I345 F346 F347 Y407	L268-Y343 HydrophobicContact CD1-CD1 4.12Å; L268-Y343 HydrophobicContact CD1-CE1 3.76Å; C327-Y343 WeakPolarHBondContact O-CE2 3.44Å; H328-Y343 PolarHBondContact ND1-OH 3.22Å; C331-Y343 HydrophobicContact CB-CD2 3.77Å; C331-Y343 HydrophobicContact CB-CE2 3.57Å; C331-Y343 HydrophobicContact CB-CG 4.37Å; S339-Y343 PolarHBondContact O-N 3.22Å; L340-Y343 WeakPolarHBondContact O-CB 3.4Å; L340-Y343 PolarHBondContact O-N 3.38Å; V341-Y343 VanDerWaalsContact C-N 3.33Å; V341-Y343 PolarHBondContact O-N 3.4Å; Y343-I345 VanDerWaalsContact C-N 3.27Å; Y343-I345 PolarHBondContact O-N 2.97Å; Y343-F346 PolarHBondContact O-N 3.08Å; Y343-F347 HydrophobicContact CE1-CB 4.42Å; Y343-F347 HydrophobicContact CE1-CD1 4.04Å; Y343-F347 HydrophobicContact CE2-CB 4.23Å; Y343-F347 AromaticContact CZ-CD1 3.88Å; Y343-F347 VanDerWaalsContact O-CB 3.25Å; Y343-F347 WeakPolarHBondContact O-CB 3.48Å; Y343-F347 PolarHBondContact O-N 3.45Å; Y343-Y407 WeakPolarHBondContact OH-CE1 3.31Å
344	A	96.5	Very high	94.7	Very high	0 Å²	0	41.8 Å²	41.8	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-61	-35.8	179.5	0	0	0	0	0	112.4	L285 I288 M289 L340 V341 G348	L285-A344 HydrophobicContact CD2-CB 4.35Å; I288-A344 HydrophobicContact CG2-CB 4.35Å; M289-A344 WeakPolarHBondContact CA-O 3.48Å; M289-A344 HydrophobicContact CB-CB 4.39Å; L340-A344 WeakPolarHBondContact O-CB 3.35Å; L340-A344 PolarHBondContact O-N 3.38Å; V341-A344 PolarHBondContact O-N 2.9Å; A344-G348 PolarHBondContact O-N 3.41Å
345	I	97.6	Very high	94.7	Very high	63 Å²	63	42.9 Å²	42.9	32%	0.323	22%	0.222	S	C	.	.	H	α-helix	trans	-64.7	-53.2	174.7	-67.7	165.4	0	0	0	110.7	I288 V292 V341 L342 Y343 F347 G348 L349	I288-I345 HydrophobicContact CG2-CG1 3.84Å; V292-I345 HydrophobicContact CG1-CG2 4.47Å; V292-I345 WeakPolarHBondContact CG1-O 3.44Å; V292-I345 HydrophobicContact CG2-CB 4.34Å; V292-I345 HydrophobicContact CG2-CG1 4.14Å; V292-I345 HydrophobicContact CG2-CG2 4.16Å; V341-I345 HydrophobicContact CG1-CD1 4.16Å; V341-I345 WeakPolarHBondContact O-CG1 3.32Å; V341-I345 PolarHBondContact O-N 3.33Å; L342-I345 PolarHBondContact O-N 3.49Å; Y343-I345 VanDerWaalsContact C-N 3.27Å; Y343-I345 PolarHBondContact O-N 2.97Å; I345-F347 VanDerWaalsContact C-N 3.33Å; I345-F347 PolarHBondContact O-N 2.94Å; I345-G348 PolarHBondContact O-N 3.39Å; I345-L349 PolarHBondContact O-N 3.47Å
346	F	97.4	Very high	94.9	Very high	106 Å²	106	37.1 Å²	37.1	47%	0.465	20%	0.198	S	C	.	.	H	α-helix	trans	-65.7	-38.2	-179.5	-73.3	-60.3	0	0	0	112.3	F323 L342 Y343 L349 G350	F323-F346 WeakPolarHBondContact CE1-O 3.47Å; F323-F346 HydrophobicContact CE2-CD1 4.44Å; F323-F346 HydrophobicContact CZ-CB 4.25Å; F323-F346 AromaticContact CZ-CD1 3.96Å; F323-F346 HydrophobicContact CZ-CD1 3.96Å; L342-F346 VanDerWaalsContact O-CD2 3.22Å; L342-F346 WeakPolarHBondContact O-CD2 3.4Å; L342-F346 PolarHBondContact O-N 2.83Å; L342-F346 VanDerWaalsContact O-N 3.12Å; Y343-F346 PolarHBondContact O-N 3.08Å; F346-L349 PolarHBondContact O-N 2.94Å; F346-G350 PolarHBondContact O-N 3.5Å
347	F	96.7	Very high	94.9	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-64.7	-43	174.6	-177.5	-157.7	0	0	0	111.4	P264 I265 M289 N324 H328 Y343 I345 L349 G350 F351	P264-F347 HydrophobicContact CB-CE1 4.33Å; P264-F347 HydrophobicContact CB-CZ 4.28Å; I265-F347 HydrophobicContact CB-CE1 3.74Å; I265-F347 HydrophobicContact CB-CZ 3.77Å; I265-F347 HydrophobicContact CG1-CE1 4.4Å; M289-F347 HydrophobicContact CE-CD1 3.27Å; M289-F347 HydrophobicContact CE-CE1 3.38Å; M289-F347 HydrophobicContact CE-CG 4.27Å; M289-F347 HydrophobicContact CE-CZ 4.43Å; M289-F347 HydrophobicContact CG-CD1 4.43Å; M289-F347 HydrophobicContact SD-CD1 3.87Å; M289-F347 HydrophobicContact SD-CE1 3.86Å; M289-F347 HydrophobicContact SD-CG 4.44Å; M289-F347 HydrophobicContact SD-CZ 4.42Å; N324-F347 WeakPolarHBondContact OD1-CD2 3.42Å; H328-F347 AromaticContact CE1-CD2 3.51Å; H328-F347 AromaticContact CE1-CE2 3.27Å; H328-F347 WeakPolarHBondContact CE1-CE2 3.39Å; H328-F347 AromaticContact CE1-CZ 3.54Å; H328-F347 AromaticContact NE2-CE2 3.7Å; Y343-F347 HydrophobicContact CE1-CB 4.42Å; Y343-F347 HydrophobicContact CE1-CD1 4.04Å; Y343-F347 HydrophobicContact CE2-CB 4.23Å; Y343-F347 AromaticContact CZ-CD1 3.88Å; Y343-F347 VanDerWaalsContact O-CB 3.25Å; Y343-F347 WeakPolarHBondContact O-CB 3.48Å; Y343-F347 PolarHBondContact O-N 3.45Å; I345-F347 VanDerWaalsContact C-N 3.33Å; I345-F347 PolarHBondContact O-N 2.94Å; F347-L349 VanDerWaalsContact C-N 3.33Å; F347-L349 PolarHBondContact O-N 2.83Å; F347-G350 PolarHBondContact O-N 3.45Å; F347-F351 HydrophobicContact CD2-CB 4.31Å; F347-F351 HydrophobicContact CE2-CB 4.13Å; F347-F351 HydrophobicContact CE2-CD2 4.07Å; F347-F351 HydrophobicContact CZ-CD2 4.38Å; F347-F351 VanDerWaalsContact O-CB 3.25Å; F347-F351 WeakPolarHBondContact O-CB 3.34Å; F347-F351 PolarHBondContact O-N 2.91Å
348	G	96.4	Very high	94.8	Very high	0 Å²	0	28.8 Å²	28.8	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-59.2	-42.6	174.5	0	0	0	0	0	112.7	M289 A344 I345 G352	M289-G348 VanDerWaalsContact CG-CA 3.5Å; A344-G348 PolarHBondContact O-N 3.41Å; I345-G348 PolarHBondContact O-N 3.39Å; G348-G352 PolarHBondContact O-N 3.27Å
349	L	96.8	Very high	94.4	Very high	65 Å²	65	26.9 Å²	26.9	34%	0.34	14%	0.142	S	C	.	.	H	α-helix	trans	-62.1	-45	174.3	-178.4	65.3	0	0	0	111.8	V292 A296 F323 I345 F346 F347 S353	V292-L349 HydrophobicContact CG1-CB 4.17Å; A296-L349 HydrophobicContact CB-CD1 3.79Å; F323-L349 HydrophobicContact CE1-CB 4.39Å; F323-L349 HydrophobicContact CE1-CD2 4.31Å; F323-L349 HydrophobicContact CE1-CG 4.31Å; F323-L349 HydrophobicContact CZ-CD2 4.12Å; I345-L349 PolarHBondContact O-N 3.47Å; F346-L349 PolarHBondContact O-N 2.94Å; F347-L349 VanDerWaalsContact C-N 3.33Å; F347-L349 PolarHBondContact O-N 2.83Å; L349-S353 WeakPolarHBondContact O-CB 3.4Å; L349-S353 PolarHBondContact O-N 3.44Å; L349-S353 PolarHBondContact O-OG 2.92Å
350	G	96.3	Very high	94	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-66.9	-46.2	179.6	0	0	0	0	0	112.4	F346 F347 G352 S353 V354	F346-G350 PolarHBondContact O-N 3.5Å; F347-G350 PolarHBondContact O-N 3.45Å; G350-G352 PolarHBondContact O-N 2.99Å; G350-S353 WeakPolarHBondContact O-CB 3.32Å; G350-S353 PolarHBondContact O-N 3.34Å; G350-V354 WeakPolarHBondContact O-CG2 3.33Å; G350-V354 PolarHBondContact O-N 3.34Å
351	F	94.6	Very high	93.7	Very high	12 Å²	12	27.6 Å²	27.6	5%	0.053	14%	0.142	C	C	.	.	H	α-helix	trans	-60.5	-44.9	177.4	-169.4	-87.7	0	0	0	111.6	K38 F261 F262 F347 S355	K38-F351 VanDerWaalsContact NZ-CZ 3.26Å; F261-F351 HydrophobicContact CD1-CE2 4.17Å; F261-F351 AromaticContact CE1-CD2 3.83Å; F261-F351 HydrophobicContact CE1-CD2 3.83Å; F261-F351 AromaticContact CE1-CE2 3.31Å; F261-F351 HydrophobicContact CE1-CE2 3.31Å; F261-F351 HydrophobicContact CE1-CZ 4.02Å; F261-F351 HydrophobicContact CE2-CD2 4.2Å; F261-F351 HydrophobicContact CE2-CE2 4.49Å; F261-F351 AromaticContact CZ-CD2 3.49Å; F261-F351 HydrophobicContact CZ-CD2 3.49Å; F261-F351 VanDerWaalsContact CZ-CD2 3.49Å; F261-F351 AromaticContact CZ-CE2 3.5Å; F261-F351 HydrophobicContact CZ-CE2 3.5Å; F261-F351 HydrophobicContact CZ-CG 4.33Å; F261-F351 HydrophobicContact CZ-CZ 4.34Å; F262-F351 HydrophobicContact CE1-CE2 4.36Å; F262-F351 HydrophobicContact CE1-CZ 4.37Å; F347-F351 HydrophobicContact CD2-CB 4.31Å; F347-F351 HydrophobicContact CE2-CB 4.13Å; F347-F351 HydrophobicContact CE2-CD2 4.07Å; F347-F351 HydrophobicContact CZ-CD2 4.38Å; F347-F351 VanDerWaalsContact O-CB 3.25Å; F347-F351 WeakPolarHBondContact O-CB 3.34Å; F347-F351 PolarHBondContact O-N 2.91Å; F351-S355 WeakPolarHBondContact CE1-OG 3.5Å; F351-S355 VanDerWaalsContact O-CB 3.25Å; F351-S355 WeakPolarHBondContact O-CB 3.22Å; F351-S355 PolarHBondContact O-N 3.03Å; F351-S355 PolarHBondContact O-OG 3.39Å
352	G	92.5	Very high	93.4	Very high	0 Å²	0	26.1 Å²	26.1	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-67.5	-35.9	176.3	0	0	0	0	0	113.8	D293 G348 G350 S356	D293-G352 WeakPolarHBondContact OD1-CA 3.28Å; D293-G352 PolarHBondContact OD1-N 3.34Å; G348-G352 PolarHBondContact O-N 3.27Å; G350-G352 PolarHBondContact O-N 2.99Å; G352-S356 WeakPolarHBondContact O-CB 3.49Å; G352-S356 PolarHBondContact O-N 3.3Å; G352-S356 PolarHBondContact O-OG 2.9Å
353	S	94.5	Very high	92.8	Very high	13 Å²	13	24 Å²	24	9%	0.091	12%	0.121	C	C	.	.	H	α-helix	trans	-62.5	-51.5	174.4	-60.7	0	0	0	0	111.6	V300 L349 G350 S356 V357	V300-S353 WeakPolarHBondContact CG2-OG 3.47Å; L349-S353 WeakPolarHBondContact O-CB 3.4Å; L349-S353 PolarHBondContact O-N 3.44Å; L349-S353 PolarHBondContact O-OG 2.92Å; G350-S353 WeakPolarHBondContact O-CB 3.32Å; G350-S353 PolarHBondContact O-N 3.34Å; S353-S356 PolarHBondContact O-N 2.89Å; S353-V357 VanDerWaalsContact O-CG2 3.3Å; S353-V357 WeakPolarHBondContact O-CG2 3.32Å; S353-V357 PolarHBondContact O-N 3.34Å
354	V	95.1	Very high	92.3	Very high	2 Å²	2	26.6 Å²	26.6	1%	0.012	14%	0.136	C	C	.	.	H	α-helix	trans	-61.7	-48.3	178.4	173.9	0	0	0	0	110.5	M257 F261 F317 A320 I321 G350 S356 V357 L358	M257-V354 HydrophobicContact CE-CG1 4.42Å; M257-V354 HydrophobicContact SD-CG1 4.08Å; F261-V354 HydrophobicContact CE2-CB 4.22Å; F261-V354 HydrophobicContact CE2-CG1 3.96Å; F261-V354 HydrophobicContact CE2-CG2 4.41Å; F261-V354 HydrophobicContact CZ-CB 4.18Å; F261-V354 HydrophobicContact CZ-CG1 3.87Å; F317-V354 HydrophobicContact CE2-CG1 4.07Å; A320-V354 HydrophobicContact CB-CG2 4.07Å; I321-V354 HydrophobicContact CG1-CG1 4.38Å; I321-V354 HydrophobicContact CG1-CG2 3.94Å; G350-V354 WeakPolarHBondContact O-CG2 3.33Å; G350-V354 PolarHBondContact O-N 3.34Å; V354-S356 VanDerWaalsContact C-N 3.29Å; V354-S356 PolarHBondContact O-N 2.81Å; V354-V357 PolarHBondContact O-N 3.31Å; V354-L358 WeakPolarHBondContact O-CB 3.46Å; V354-L358 PolarHBondContact O-N 3.4Å
355	S	90.1	Very high	91.8	Very high	29 Å²	29	27.4 Å²	27.4	20%	0.203	14%	0.14	C	C	.	.	H	α-helix	trans	-61.3	-35.7	-177	-62.1	0	0	0	0	113.2	F351	F351-S355 WeakPolarHBondContact CE1-OG 3.5Å; F351-S355 VanDerWaalsContact O-CB 3.25Å; F351-S355 WeakPolarHBondContact O-CB 3.22Å; F351-S355 PolarHBondContact O-N 3.03Å; F351-S355 PolarHBondContact O-OG 3.39Å
356	S	88.4	Confident	91.3	Very high	24 Å²	24	25.4 Å²	25.4	17%	0.168	13%	0.131	C	C	.	.	H	α-helix	trans	-72.8	-41.1	179.8	-56.9	0	0	0	0	112.2	R297 G352 S353 V354	R297-S356 WeakPolarHBondContact CA-OG 3.16Å; R297-S356 VanDerWaalsContact CB-OG 3.25Å; R297-S356 WeakPolarHBondContact CB-OG 3.31Å; R297-S356 WeakPolarHBondContact CG-OG 3.05Å; R297-S356 PolarHBondContact O-OG 3.09Å; G352-S356 WeakPolarHBondContact O-CB 3.49Å; G352-S356 PolarHBondContact O-N 3.3Å; G352-S356 PolarHBondContact O-OG 2.9Å; S353-S356 PolarHBondContact O-N 2.89Å; V354-S356 VanDerWaalsContact C-N 3.29Å; V354-S356 PolarHBondContact O-N 2.81Å
357	V	91.4	Very high	90.4	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-87.9	-18.9	-171.7	-175.8	0	0	0	0	112.2	V300 A304 I313 F316 F317 S353 V354 E360 T361	V300-V357 HydrophobicContact CG1-CG2 3.96Å; A304-V357 HydrophobicContact CB-CG2 4.2Å; I313-V357 HydrophobicContact CD1-CG1 4.31Å; I313-V357 HydrophobicContact CG1-CG1 3.88Å; F316-V357 HydrophobicContact CD1-CG1 4.2Å; F316-V357 HydrophobicContact CD1-CG2 3.84Å; F316-V357 HydrophobicContact CE1-CG2 3.64Å; F317-V357 HydrophobicContact CB-CG1 3.74Å; F317-V357 HydrophobicContact CD2-CB 4.04Å; F317-V357 HydrophobicContact CD2-CG1 3.92Å; F317-V357 HydrophobicContact CG-CG1 4.24Å; S353-V357 VanDerWaalsContact O-CG2 3.3Å; S353-V357 WeakPolarHBondContact O-CG2 3.32Å; S353-V357 PolarHBondContact O-N 3.34Å; V354-V357 PolarHBondContact O-N 3.31Å; V357-E360 PolarHBondContact O-N 3.46Å; V357-T361 WeakPolarHBondContact CG1-OG1 3.19Å; V357-T361 WeakPolarHBondContact O-CB 3.21Å; V357-T361 PolarHBondContact O-N 3.38Å; V357-T361 PolarHBondContact O-OG1 2.82Å
358	L	92.1	Very high	89.3	Confident	16 Å²	16	24.3 Å²	24.3	8%	0.084	14%	0.144	C	C	.	.	H	α-helix	trans	-50.6	-61.9	179.9	-174.9	73.1	0	0	0	112.3	Y250 N254 F258 F317 V354 T361 L362	Y250-L358 WeakPolarHBondContact OH-CD1 3.2Å; Y250-L358 WeakPolarHBondContact OH-CG 3.28Å; Y250-L358 PolarHBondContact OH-O 2.84Å; Y250-L358 VanDerWaalsContact OH-O 3.13Å; N254-L358 WeakPolarHBondContact ND2-CD1 3.47Å; F258-L358 HydrophobicContact CZ-CD2 4.24Å; F317-L358 HydrophobicContact CE2-CB 4.19Å; F317-L358 HydrophobicContact CE2-CD1 3.95Å; F317-L358 HydrophobicContact CZ-CD1 3.55Å; V354-L358 WeakPolarHBondContact O-CB 3.46Å; V354-L358 PolarHBondContact O-N 3.4Å; L358-T361 PolarHBondContact O-N 3.36Å; L358-L362 PolarHBondContact O-N 3.33Å
359	F	85.6	Confident	88.1	Confident	62 Å²	62	30.3 Å²	30.3	27%	0.272	18%	0.183	S	C	.	.	H	α-helix	trans	-74.5	-27.5	-177.6	-67.5	-60.3	0	0	0	113.2	M363 F371 V375	F359-M363 VanDerWaalsContact O-CB 3.31Å; F359-M363 WeakPolarHBondContact O-CB 3.11Å; F359-M363 PolarHBondContact O-N 2.91Å; F359-F371 HydrophobicContact CB-CZ 4.21Å; F359-F371 HydrophobicContact CD1-CZ 4.41Å; F359-F371 WeakPolarHBondContact O-CE2 3.15Å; F359-V375 HydrophobicContact CD1-CG2 4.19Å; F359-V375 HydrophobicContact CE1-CG1 4.18Å; F359-V375 HydrophobicContact CE1-CG2 4.32Å
360	E	85.8	Confident	87.3	Confident	47 Å²	47	33 Å²	33	22%	0.22	19%	0.188	C	C	.	.	H	α-helix	trans	-66.5	-40.9	174.5	-71.5	-156.6	-178	0	0	112	N305 R310 I313 V357 M363 D364	N305-E360 PolarHBondContact ND2-OE1 3.05Å; N305-E360 PolarHBondContact ND2-OE2 3.05Å; R310-E360 IonicContact NH1-OE2 3.95Å; R310-E360 PolarHBondContact NH1-OE2 3.22Å; I313-E360 HydrophobicContact CD1-CB 3.77Å; V357-E360 PolarHBondContact O-N 3.46Å; E360-M363 PolarHBondContact O-N 2.98Å; E360-D364 WeakPolarHBondContact O-CB 3.42Å; E360-D364 PolarHBondContact O-N 3.34Å
361	T	90.6	Very high	86.3	Confident	1 Å²	1	35.5 Å²	35.5	1%	0.006	20%	0.199	C	C	.	.	H	α-helix	trans	-65.6	-43	176.8	-57.6	0	0	0	0	110.7	Y250 Q314 F317 V357 L358 M363 D364 L365	Y250-T361 HydrophobicContact CD2-CG2 4.11Å; Y250-T361 HydrophobicContact CE2-CG2 4.16Å; Q314-T361 HydrophobicContact CB-CG2 4.41Å; Q314-T361 HydrophobicContact CG-CG2 3.74Å; F317-T361 HydrophobicContact CB-CG2 4.49Å; F317-T361 HydrophobicContact CD1-CG2 4.34Å; V357-T361 WeakPolarHBondContact CG1-OG1 3.19Å; V357-T361 WeakPolarHBondContact O-CB 3.21Å; V357-T361 PolarHBondContact O-N 3.38Å; V357-T361 PolarHBondContact O-OG1 2.82Å; L358-T361 PolarHBondContact O-N 3.36Å; T361-M363 VanDerWaalsContact C-N 3.34Å; T361-M363 PolarHBondContact O-N 3.23Å; T361-D364 PolarHBondContact O-N 3Å; T361-L365 HydrophobicContact CG2-CD1 4.05Å; T361-L365 WeakPolarHBondContact O-CB 3.46Å; T361-L365 WeakPolarHBondContact O-CG 3.48Å; T361-L365 PolarHBondContact O-N 2.83Å
362	L	89.4	Confident	85.3	Confident	0 Å²	0	39.4 Å²	39.4	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-61.6	-42.1	174.8	-177.9	60.1	0	0	0	112.2	F247 Y250 L358 D364 L365 V366 F371 A374 V375 V378	F247-L362 HydrophobicContact CD2-CD1 3.97Å; F247-L362 HydrophobicContact CE2-CD1 3.98Å; Y250-L362 HydrophobicContact CD1-CD1 4.01Å; Y250-L362 HydrophobicContact CE1-CB 4.21Å; Y250-L362 HydrophobicContact CE1-CD1 3.81Å; Y250-L362 HydrophobicContact CE1-CD2 4.47Å; Y250-L362 HydrophobicContact CE1-CG 4.38Å; Y250-L362 HydrophobicContact CE2-CB 4.46Å; L358-L362 PolarHBondContact O-N 3.33Å; L362-D364 VanDerWaalsContact C-N 3.34Å; L362-L365 PolarHBondContact O-N 3.14Å; L362-V366 HydrophobicContact CD1-CG2 3.9Å; L362-V366 WeakPolarHBondContact O-CB 3.36Å; L362-V366 PolarHBondContact O-N 3.38Å; L362-F371 HydrophobicContact CB-CE2 4.26Å; L362-F371 HydrophobicContact CD2-CE2 4.2Å; L362-F371 HydrophobicContact CG-CD2 4.33Å; L362-F371 HydrophobicContact CG-CE2 4.14Å; L362-A374 HydrophobicContact CD1-CB 4.16Å; L362-A374 HydrophobicContact CD2-CB 4.46Å; L362-A374 HydrophobicContact CG-CB 4.48Å; L362-V375 HydrophobicContact CD2-CG2 3.76Å; L362-V378 HydrophobicContact CD1-CG2 4.34Å; L362-V378 HydrophobicContact CD2-CG2 4.21Å
363	M	83.8	Confident	84.7	Confident	50 Å²	50	40.3 Å²	40.3	25%	0.246	23%	0.234	C	C	.	.	H	α-helix	trans	-63.8	-38.5	177	-176.6	67.1	172.3	0	0	112.2	P2 F359 E360 T361 G367 A368 F371	P2-M363 HydrophobicContact CG-CE 4.43Å; F359-M363 VanDerWaalsContact O-CB 3.31Å; F359-M363 WeakPolarHBondContact O-CB 3.11Å; F359-M363 PolarHBondContact O-N 2.91Å; E360-M363 PolarHBondContact O-N 2.98Å; T361-M363 VanDerWaalsContact C-N 3.34Å; T361-M363 PolarHBondContact O-N 3.23Å; M363-G367 WeakPolarHBondContact O-CA 3.34Å; M363-G367 PolarHBondContact O-N 3.29Å; M363-A368 HydrophobicContact CE-CB 3.41Å; M363-A368 VanDerWaalsContact CE-CB 3.41Å; M363-A368 HydrophobicContact SD-CB 4.47Å; M363-F371 HydrophobicContact CB-CD2 3.77Å; M363-F371 HydrophobicContact CB-CE2 3.72Å; M363-F371 HydrophobicContact CG-CD2 4.29Å; M363-F371 HydrophobicContact SD-CB 3.63Å; M363-F371 HydrophobicContact SD-CD1 4.12Å; M363-F371 HydrophobicContact SD-CD2 3.58Å; M363-F371 VanDerWaalsContact SD-CD2 3.58Å; M363-F371 HydrophobicContact SD-CE2 4.25Å; M363-F371 HydrophobicContact SD-CG 3.49Å; M363-F371 WeakPolarHBondContact SD-CG 3.22Å
364	D	87.2	Confident	84.3	Confident	68 Å²	68	39.7 Å²	39.7	36%	0.364	23%	0.23	S	C	.	.	H	α-helix	trans	-68.9	-38.5	176.9	-164.6	72.4	0	0	0	112.2	R310 I313 Q314 E360 T361 L362	R310-D364 IonicContact NH2-OD1 3.64Å; I313-D364 HydrophobicContact CG2-CB 4.13Å; Q314-D364 PolarHBondContact NE2-OD2 2.89Å; E360-D364 WeakPolarHBondContact O-CB 3.42Å; E360-D364 PolarHBondContact O-N 3.34Å; T361-D364 PolarHBondContact O-N 3Å; L362-D364 VanDerWaalsContact C-N 3.34Å
365	L	86.8	Confident	83.7	Confident	18 Å²	18	41 Å²	41	9%	0.094	24%	0.238	C	C	.	.	H	α-helix	trans	-72.8	-42.2	179.9	-75.5	169.4	0	0	0	113.7	H244 Y250 Q314 T361 L362	H244-L365 PolarHBondContact CE1-O 3.28Å; H244-L365 VanDerWaalsContact CE1-O 3.24Å; Y250-L365 HydrophobicContact CD2-CD1 3.86Å; Y250-L365 HydrophobicContact CG-CD1 3.93Å; Q314-L365 HydrophobicContact CG-CD2 4.32Å; Q314-L365 HydrophobicContact CG-CG 4.43Å; T361-L365 HydrophobicContact CG2-CD1 4.05Å; T361-L365 WeakPolarHBondContact O-CB 3.46Å; T361-L365 WeakPolarHBondContact O-CG 3.48Å; T361-L365 PolarHBondContact O-N 2.83Å; L362-L365 PolarHBondContact O-N 3.14Å
366	V	86	Confident	83.4	Confident	21 Å²	21	40.2 Å²	40.2	13%	0.127	24%	0.235	C	C	.	.	H	α-helix	trans	-100.8	-25.4	-171.4	174.4	0	0	0	0	112.5	L241 F247 L362 R370 A374	L241-V366 HydrophobicContact CD2-CG1 3.61Å; L241-V366 HydrophobicContact CD2-CG2 4.17Å; F247-V366 HydrophobicContact CB-CG2 4.45Å; F247-V366 HydrophobicContact CD2-CG2 3.78Å; F247-V366 HydrophobicContact CG-CG2 4.47Å; L362-V366 HydrophobicContact CD1-CG2 3.9Å; L362-V366 WeakPolarHBondContact O-CB 3.36Å; L362-V366 PolarHBondContact O-N 3.38Å; V366-R370 HydrophobicContact CG1-CB 3.42Å; V366-R370 VanDerWaalsContact CG1-CB 3.42Å; V366-A374 HydrophobicContact CB-CB 4.33Å; V366-A374 HydrophobicContact CG1-CB 3.93Å; V366-A374 HydrophobicContact CG2-CB 4.03Å
367	G	79	Confident	83.4	Confident	26 Å²	26	39.4 Å²	39.4	27%	0.268	23%	0.229	S	C	.	.			trans	79.6	162.6	-175.5	0	0	0	0	0	114	M363 P369 R370 F371	M363-G367 WeakPolarHBondContact O-CA 3.34Å; M363-G367 PolarHBondContact O-N 3.29Å; G367-P369 VanDerWaalsContact C-CD 3.45Å; G367-R370 PolarHBondContact O-N 3.28Å; G367-F371 PolarHBondContact O-N 3.28Å; G367-F371 VanDerWaalsContact O-N 3.16Å
368	A	72.9	Confident	83.3	Confident	57 Å²	57	39.5 Å²	39.5	47%	0.471	23%	0.229	S	C	.	.	T	Hydrogen-bonded Turn	trans	-53.4	-45.6	-175.7	0	0	0	0	0	116.6	M363 R370 F371	M363-A368 HydrophobicContact CE-CB 3.41Å; M363-A368 VanDerWaalsContact CE-CB 3.41Å; M363-A368 HydrophobicContact SD-CB 4.47Å; A368-R370 VanDerWaalsContact C-N 3.31Å; A368-R370 PolarHBondContact O-N 3.4Å; A368-F371 PolarHBondContact O-N 3.45Å
369	P	72.4	Confident	83.1	Confident	126 Å²	126	39.7 Å²	39.7	82%	0.818	23%	0.231	S	C	*	.	T	Hydrogen-bonded Turn	trans	-69.9	-28.7	-171.4	26.2	-33.9	0	0	0	113.1	G367	G367-P369 VanDerWaalsContact C-CD 3.45Å
370	R	78.8	Confident	83.2	Confident	120 Å²	120	39.9 Å²	39.9	45%	0.453	24%	0.237	S	C	.	.	T	Hydrogen-bonded Turn	trans	-102.8	-5.2	-177.6	-67.3	-176.9	-176.3	-173.1	-1	113.5	L241 V366 G367 A368 S372 S373 A374	L241-R370 HydrophobicContact CD2-CB 4.39Å; V366-R370 HydrophobicContact CG1-CB 3.42Å; V366-R370 VanDerWaalsContact CG1-CB 3.42Å; G367-R370 PolarHBondContact O-N 3.28Å; A368-R370 VanDerWaalsContact C-N 3.31Å; A368-R370 PolarHBondContact O-N 3.4Å; R370-S372 PolarHBondContact O-N 3.27Å; R370-S373 PolarHBondContact O-N 2.95Å; R370-S373 VanDerWaalsContact O-N 3.16Å; R370-A374 PolarHBondContact O-N 3.34Å
371	F	76.4	Confident	83.5	Confident	53 Å²	53	40.2 Å²	40.2	23%	0.232	24%	0.242	C	C	.	.	H	α-helix	trans	-54.8	-48	-175.8	-179.5	-107.4	0	0	0	113.7	F359 L362 M363 G367 A368 S373 A374 V375	F359-F371 HydrophobicContact CB-CZ 4.21Å; F359-F371 HydrophobicContact CD1-CZ 4.41Å; F359-F371 WeakPolarHBondContact O-CE2 3.15Å; L362-F371 HydrophobicContact CB-CE2 4.26Å; L362-F371 HydrophobicContact CD2-CE2 4.2Å; L362-F371 HydrophobicContact CG-CD2 4.33Å; L362-F371 HydrophobicContact CG-CE2 4.14Å; M363-F371 HydrophobicContact CB-CD2 3.77Å; M363-F371 HydrophobicContact CB-CE2 3.72Å; M363-F371 HydrophobicContact CG-CD2 4.29Å; M363-F371 HydrophobicContact SD-CB 3.63Å; M363-F371 HydrophobicContact SD-CD1 4.12Å; M363-F371 HydrophobicContact SD-CD2 3.58Å; M363-F371 VanDerWaalsContact SD-CD2 3.58Å; M363-F371 HydrophobicContact SD-CE2 4.25Å; M363-F371 HydrophobicContact SD-CG 3.49Å; M363-F371 WeakPolarHBondContact SD-CG 3.22Å; G367-F371 PolarHBondContact O-N 3.28Å; G367-F371 VanDerWaalsContact O-N 3.16Å; A368-F371 PolarHBondContact O-N 3.45Å; F371-S373 VanDerWaalsContact C-N 3.25Å; F371-S373 PolarHBondContact O-N 2.83Å; F371-A374 PolarHBondContact O-N 3.25Å; F371-V375 HydrophobicContact CD1-CG2 4.22Å; F371-V375 HydrophobicContact CD2-CG2 4.22Å; F371-V375 HydrophobicContact CE1-CG2 3.79Å; F371-V375 HydrophobicContact CE2-CG2 3.8Å; F371-V375 HydrophobicContact CG-CG2 4.42Å; F371-V375 HydrophobicContact CZ-CG2 3.57Å; F371-V375 WeakPolarHBondContact O-CG2 3.36Å; F371-V375 PolarHBondContact O-N 3.23Å
372	S	72.9	Confident	83.6	Confident	95 Å²	95	40.3 Å²	40.3	66%	0.664	24%	0.243	S	C	*	.	H	α-helix	trans	-62.3	-33.6	-178.3	-174.7	0	0	0	0	112.9	R370 G376	R370-S372 PolarHBondContact O-N 3.27Å; S372-G376 PolarHBondContact O-N 2.85Å
373	S	80.2	Confident	83.7	Confident	18 Å²	18	41.4 Å²	41.4	13%	0.126	25%	0.25	C	C	.	.	H	α-helix	trans	-76.7	-39.3	177.8	-165.1	0	0	0	0	110.9	Y236 D238 R370 F371 G376 L377	Y236-S373 PolarHBondContact O-OG 3.4Å; D238-S373 WeakPolarHBondContact CB-OG 3.32Å; D238-S373 PolarHBondContact N-OG 2.96Å; R370-S373 PolarHBondContact O-N 2.95Å; R370-S373 VanDerWaalsContact O-N 3.16Å; F371-S373 VanDerWaalsContact C-N 3.25Å; F371-S373 PolarHBondContact O-N 2.83Å; S373-G376 PolarHBondContact O-N 3.24Å; S373-L377 PolarHBondContact O-N 3.43Å
374	A	84.9	Confident	84.2	Confident	0 Å²	0	40.6 Å²	40.6	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-62.2	-43.4	175.8	0	0	0	0	0	112.7	L241 F247 L362 V366 R370 F371 G376 L377 V378	L241-A374 HydrophobicContact CD1-CB 3.74Å; F247-A374 HydrophobicContact CE2-CB 4Å; L362-A374 HydrophobicContact CD1-CB 4.16Å; L362-A374 HydrophobicContact CD2-CB 4.46Å; L362-A374 HydrophobicContact CG-CB 4.48Å; V366-A374 HydrophobicContact CB-CB 4.33Å; V366-A374 HydrophobicContact CG1-CB 3.93Å; V366-A374 HydrophobicContact CG2-CB 4.03Å; R370-A374 PolarHBondContact O-N 3.34Å; F371-A374 PolarHBondContact O-N 3.25Å; A374-G376 VanDerWaalsContact C-N 3.33Å; A374-G376 PolarHBondContact O-N 3.47Å; A374-L377 PolarHBondContact O-N 3.43Å; A374-V378 WeakPolarHBondContact O-CB 3.39Å; A374-V378 WeakPolarHBondContact O-CG2 3.18Å; A374-V378 PolarHBondContact O-N 3.47Å
375	V	84.1	Confident	84.6	Confident	29 Å²	29	38 Å²	38	18%	0.176	24%	0.242	C	C	.	.	H	α-helix	trans	-57.1	-48.2	174.4	171.5	0	0	0	0	110.4	F359 L362 F371 L377 V378 T379	F359-V375 HydrophobicContact CD1-CG2 4.19Å; F359-V375 HydrophobicContact CE1-CG1 4.18Å; F359-V375 HydrophobicContact CE1-CG2 4.32Å; L362-V375 HydrophobicContact CD2-CG2 3.76Å; F371-V375 HydrophobicContact CD1-CG2 4.22Å; F371-V375 HydrophobicContact CD2-CG2 4.22Å; F371-V375 HydrophobicContact CE1-CG2 3.79Å; F371-V375 HydrophobicContact CE2-CG2 3.8Å; F371-V375 HydrophobicContact CG-CG2 4.42Å; F371-V375 HydrophobicContact CZ-CG2 3.57Å; F371-V375 WeakPolarHBondContact O-CG2 3.36Å; F371-V375 PolarHBondContact O-N 3.23Å; V375-L377 VanDerWaalsContact C-N 3.34Å; V375-L377 PolarHBondContact O-N 3.09Å; V375-V378 PolarHBondContact O-N 3.45Å; V375-T379 HydrophobicContact CG1-CG2 4.24Å; V375-T379 WeakPolarHBondContact O-CG2 3.39Å; V375-T379 PolarHBondContact O-N 2.81Å; V375-T379 PolarHBondContact O-OG1 2.88Å; V375-T379 VanDerWaalsContact O-OG1 3.05Å
376	G	83.3	Confident	85	Confident	14 Å²	14	37.2 Å²	37.2	14%	0.144	24%	0.238	C	C	.	.	H	α-helix	trans	-61.7	-39.2	179.3	0	0	0	0	0	113.6	S372 S373 A374 T379 V380	S372-G376 PolarHBondContact O-N 2.85Å; S373-G376 PolarHBondContact O-N 3.24Å; A374-G376 VanDerWaalsContact C-N 3.33Å; A374-G376 PolarHBondContact O-N 3.47Å; G376-T379 PolarHBondContact O-OG1 3.33Å; G376-T379 VanDerWaalsContact O-OG1 3.05Å; G376-V380 VanDerWaalsContact O-CG2 3.25Å; G376-V380 WeakPolarHBondContact O-CG2 3.14Å; G376-V380 PolarHBondContact O-N 2.92Å
377	L	87.1	Confident	85.4	Confident	7 Å²	7	38.7 Å²	38.7	4%	0.037	24%	0.244	C	C	.	.	H	α-helix	trans	-66.1	-46.1	176.3	-137.3	71.1	0	0	0	111.1	L237 F239 L241 F242 F247 S373 A374 V375 V380 V381	L237-L377 HydrophobicContact CB-CD1 3.69Å; L237-L377 HydrophobicContact CD2-CD1 3.73Å; L237-L377 HydrophobicContact CG-CD1 4.15Å; F239-L377 HydrophobicContact CE1-CD1 4.39Å; L241-L377 HydrophobicContact CB-CD2 4.19Å; L241-L377 HydrophobicContact CD1-CD2 4.46Å; F242-L377 HydrophobicContact CD2-CD2 3.86Å; F242-L377 HydrophobicContact CE1-CD2 4.36Å; F242-L377 HydrophobicContact CE2-CD1 4.26Å; F242-L377 HydrophobicContact CE2-CD2 3.33Å; F242-L377 HydrophobicContact CE2-CG 3.84Å; F242-L377 HydrophobicContact CZ-CD2 3.62Å; F242-L377 HydrophobicContact CZ-CG 3.93Å; F247-L377 HydrophobicContact CE1-CD2 3.98Å; F247-L377 HydrophobicContact CZ-CB 4.31Å; F247-L377 HydrophobicContact CZ-CD2 4Å; S373-L377 PolarHBondContact O-N 3.43Å; A374-L377 PolarHBondContact O-N 3.43Å; V375-L377 VanDerWaalsContact C-N 3.34Å; V375-L377 PolarHBondContact O-N 3.09Å; L377-V380 PolarHBondContact O-N 3.48Å; L377-V381 WeakPolarHBondContact O-CG2 3.41Å; L377-V381 PolarHBondContact O-N 3.45Å; L377-V381 VanDerWaalsContact O-N 3.17Å
378	V	90.1	Very high	86.2	Confident	1 Å²	1	41.2 Å²	41.2	1%	0.006	25%	0.251	C	S	.	.	H	α-helix	trans	-61.1	-50.6	179.1	167.9	0	0	0	0	110.5	F247 Y250 L251 L362 A374 V375 V380 V381 E382	F247-V378 HydrophobicContact CE2-CG2 3.57Å; F247-V378 HydrophobicContact CZ-CG2 3.83Å; Y250-V378 HydrophobicContact CE1-CG1 4.36Å; Y250-V378 HydrophobicContact CE1-CG2 4.16Å; L251-V378 HydrophobicContact CD1-CB 4.43Å; L251-V378 HydrophobicContact CD1-CG2 4.01Å; L362-V378 HydrophobicContact CD1-CG2 4.34Å; L362-V378 HydrophobicContact CD2-CG2 4.21Å; A374-V378 WeakPolarHBondContact O-CB 3.39Å; A374-V378 WeakPolarHBondContact O-CG2 3.18Å; A374-V378 PolarHBondContact O-N 3.47Å; V375-V378 PolarHBondContact O-N 3.45Å; V378-V380 VanDerWaalsContact C-N 3.29Å; V378-V380 PolarHBondContact O-N 3.5Å; V378-V381 PolarHBondContact O-N 3.07Å; V378-V381 VanDerWaalsContact O-N 3.14Å; V378-E382 HydrophobicContact CG1-CG 4.03Å; V378-E382 WeakPolarHBondContact CG1-OE1 3.48Å; V378-E382 WeakPolarHBondContact O-CB 3.37Å; V378-E382 VanDerWaalsContact O-CG 3.25Å; V378-E382 WeakPolarHBondContact O-CG 3.49Å; V378-E382 PolarHBondContact O-N 2.97Å
379	T	87.8	Confident	87.3	Confident	21 Å²	21	38.6 Å²	38.6	13%	0.129	23%	0.23	C	C	.	.	H	α-helix	trans	-62.7	-34	-178.1	52.2	0	0	0	0	113.2	V375 G376 C383	V375-T379 HydrophobicContact CG1-CG2 4.24Å; V375-T379 WeakPolarHBondContact O-CG2 3.39Å; V375-T379 PolarHBondContact O-N 2.81Å; V375-T379 PolarHBondContact O-OG1 2.88Å; V375-T379 VanDerWaalsContact O-OG1 3.05Å; G376-T379 PolarHBondContact O-OG1 3.33Å; G376-T379 VanDerWaalsContact O-OG1 3.05Å; T379-C383 PolarHBondContact O-N 3Å
380	V	88.6	Confident	88.4	Confident	66 Å²	66	32.7 Å²	32.7	40%	0.4	19%	0.191	S	C	.	.	H	α-helix	trans	-69.2	-42.1	176.4	170	0	0	0	0	111	P74 G376 L377 V378 C383	P74-V380 HydrophobicContact CG-CG2 3.57Å; G376-V380 VanDerWaalsContact O-CG2 3.25Å; G376-V380 WeakPolarHBondContact O-CG2 3.14Å; G376-V380 PolarHBondContact O-N 2.92Å; L377-V380 PolarHBondContact O-N 3.48Å; V378-V380 VanDerWaalsContact C-N 3.29Å; V378-V380 PolarHBondContact O-N 3.5Å; V380-C383 WeakPolarHBondContact O-CB 3.26Å; V380-C383 PolarHBondContact O-N 3.23Å
381	V	91.6	Very high	89.2	Confident	54 Å²	54	27.1 Å²	27.1	33%	0.327	17%	0.171	S	C	.	.	H	α-helix	trans	-72.3	-37.8	179.3	175.3	0	0	0	0	111.2	L251 V255 L377 V378 C383 G384 P385	L251-V381 HydrophobicContact CD1-CB 4.02Å; L251-V381 HydrophobicContact CD1-CG1 3.96Å; L251-V381 HydrophobicContact CD2-CG1 4.37Å; L251-V381 HydrophobicContact CD2-CG2 4.47Å; L251-V381 HydrophobicContact CG-CG1 4.27Å; V255-V381 HydrophobicContact CG2-CG1 3.56Å; L377-V381 WeakPolarHBondContact O-CG2 3.41Å; L377-V381 PolarHBondContact O-N 3.45Å; L377-V381 VanDerWaalsContact O-N 3.17Å; V378-V381 PolarHBondContact O-N 3.07Å; V378-V381 VanDerWaalsContact O-N 3.14Å; V381-C383 PolarHBondContact O-N 2.94Å; V381-G384 PolarHBondContact O-N 3.22Å; V381-P385 WeakPolarHBondContact O-CD 3.29Å
382	E	91.4	Very high	90.2	Very high	3 Å²	3	29.3 Å²	29.3	1%	0.014	18%	0.184	C	C	.	.	H	α-helix	trans	-64.2	-21.3	175.8	-73.4	174.9	174.5	0	0	112.9	N254 F258 V378 G384 P385 V386	N254-E382 PolarHBondContact ND2-OE1 3.19Å; F258-E382 HydrophobicContact CD2-CB 4.3Å; F258-E382 HydrophobicContact CD2-CG 3.68Å; F258-E382 HydrophobicContact CE2-CG 3.89Å; F258-E382 WeakPolarHBondContact CE2-OE1 3.48Å; V378-E382 HydrophobicContact CG1-CG 4.03Å; V378-E382 WeakPolarHBondContact CG1-OE1 3.48Å; V378-E382 WeakPolarHBondContact O-CB 3.37Å; V378-E382 VanDerWaalsContact O-CG 3.25Å; V378-E382 WeakPolarHBondContact O-CG 3.49Å; V378-E382 PolarHBondContact O-N 2.97Å; E382-G384 VanDerWaalsContact C-N 3.26Å; E382-G384 PolarHBondContact O-N 3.19Å; E382-P385 WeakPolarHBondContact O-CD 3.39Å; E382-V386 WeakPolarHBondContact O-CB 3.31Å; E382-V386 WeakPolarHBondContact O-CG2 3.31Å; E382-V386 PolarHBondContact O-N 2.89Å
383	C	91.9	Very high	91.2	Very high	22 Å²	22	25.2 Å²	25.2	15%	0.149	16%	0.157	C	C	.	.	H	α-helix	trans	-56.1	-37.6	175.1	-179.2	0	0	0	0	113	A67 A71 T379 V380 V381 L387	A67-C383 PolarHBondContact O-SG 3.46Å; A67-C383 VanDerWaalsContact O-SG 3.36Å; A71-C383 HydrophobicContact CB-CB 4.43Å; T379-C383 PolarHBondContact O-N 3Å; V380-C383 WeakPolarHBondContact O-CB 3.26Å; V380-C383 PolarHBondContact O-N 3.23Å; V381-C383 PolarHBondContact O-N 2.94Å; C383-L387 VanDerWaalsContact O-CB 3.22Å; C383-L387 WeakPolarHBondContact O-CB 3.46Å; C383-L387 PolarHBondContact O-N 3.05Å
384	G	94.6	Very high	91.9	Very high	34 Å²	34	24.4 Å²	24.4	35%	0.351	15%	0.151	S	C	.	.	H	α-helix	trans	-62.6	-57.6	-178.1	0	0	0	0	0	112.5	V381 E382 V386 L387 L388	V381-G384 PolarHBondContact O-N 3.22Å; E382-G384 VanDerWaalsContact C-N 3.26Å; E382-G384 PolarHBondContact O-N 3.19Å; G384-V386 VanDerWaalsContact C-N 3.33Å; G384-V386 PolarHBondContact O-N 3.45Å; G384-L387 PolarHBondContact O-N 3.38Å; G384-L388 WeakPolarHBondContact O-CG 3.26Å; G384-L388 PolarHBondContact O-N 3.43Å; G384-L388 VanDerWaalsContact O-N 3.08Å
385	P	95.6	Very high	92.4	Very high	14 Å²	14	29.9 Å²	29.9	9%	0.091	17%	0.174	C	C	.	.	H	α-helix	trans	-59.4	-39.1	176	-27.3	35.3	0	0	0	113.9	V255 F258 L259 V381 E382 L387 L388 G389	V255-P385 HydrophobicContact CB-CG 4.21Å; V255-P385 HydrophobicContact CG1-CG 3.71Å; V255-P385 HydrophobicContact CG2-CG 4.42Å; V255-P385 WeakPolarHBondContact O-CB 3.43Å; V255-P385 VanDerWaalsContact O-CG 3.29Å; V255-P385 WeakPolarHBondContact O-CG 3.47Å; F258-P385 HydrophobicContact CB-CB 3.95Å; L259-P385 HydrophobicContact CB-CB 4.27Å; L259-P385 HydrophobicContact CD1-CB 4.41Å; V381-P385 WeakPolarHBondContact O-CD 3.29Å; E382-P385 WeakPolarHBondContact O-CD 3.39Å; P385-L387 VanDerWaalsContact C-N 3.33Å; P385-L387 PolarHBondContact O-N 3.37Å; P385-L388 PolarHBondContact O-N 2.99Å; P385-G389 WeakPolarHBondContact O-CA 3.47Å; P385-G389 PolarHBondContact O-N 3.13Å
386	V	94.4	Very high	92.9	Very high	1 Å²	1	31.1 Å²	31.1	1%	0.006	18%	0.18	C	C	.	.	H	α-helix	trans	-67.1	-35.7	179	174.3	0	0	0	0	111.9	S63 L66 F258 F262 E382 G384 P390	S63-V386 PolarHBondContact OG-O 2.82Å; L66-V386 HydrophobicContact CB-CG1 3.52Å; L66-V386 HydrophobicContact CD2-CG1 4.06Å; L66-V386 HydrophobicContact CG-CG1 4.44Å; F258-V386 HydrophobicContact CB-CG2 4.16Å; F258-V386 HydrophobicContact CD1-CG2 4.11Å; F258-V386 HydrophobicContact CG-CG2 4.32Å; F262-V386 HydrophobicContact CD2-CG1 4.17Å; F262-V386 HydrophobicContact CD2-CG2 3.82Å; F262-V386 HydrophobicContact CE2-CG1 4.36Å; F262-V386 HydrophobicContact CE2-CG2 3.7Å; E382-V386 WeakPolarHBondContact O-CB 3.31Å; E382-V386 WeakPolarHBondContact O-CG2 3.31Å; E382-V386 PolarHBondContact O-N 2.89Å; G384-V386 VanDerWaalsContact C-N 3.33Å; G384-V386 PolarHBondContact O-N 3.45Å; V386-P390 WeakPolarHBondContact O-CD 3.4Å
387	L	96.1	Very high	93.4	Very high	51 Å²	51	30.5 Å²	30.5	27%	0.267	17%	0.173	S	C	.	.	H	α-helix	trans	-68.3	-43	175.6	-176.7	61.6	0	0	0	111.9	W60 S63 I64 A67 C383 G384 P385 P391	W60-L387 HydrophobicContact CE3-CD1 4.07Å; W60-L387 HydrophobicContact CZ3-CD1 3.71Å; W60-L387 HydrophobicContact CZ3-CD2 4.44Å; W60-L387 HydrophobicContact CZ3-CG 3.79Å; S63-L387 VanDerWaalsContact CB-O 3.28Å; S63-L387 WeakPolarHBondContact CB-O 3.43Å; S63-L387 PolarHBondContact OG-O 2.65Å; I64-L387 HydrophobicContact CB-CD1 4.43Å; I64-L387 HydrophobicContact CG1-CD1 3.79Å; A67-L387 HydrophobicContact CB-CB 3.77Å; A67-L387 HydrophobicContact CB-CD1 3.81Å; A67-L387 HydrophobicContact CB-CG 4.29Å; C383-L387 VanDerWaalsContact O-CB 3.22Å; C383-L387 WeakPolarHBondContact O-CB 3.46Å; C383-L387 PolarHBondContact O-N 3.05Å; G384-L387 PolarHBondContact O-N 3.38Å; P385-L387 VanDerWaalsContact C-N 3.33Å; P385-L387 PolarHBondContact O-N 3.37Å; L387-P391 WeakPolarHBondContact O-CD 3.47Å; L387-P391 WeakPolarHBondContact O-CG 3.48Å
388	L	96	Very high	93.7	Very high	80 Å²	80	32.8 Å²	32.8	42%	0.419	19%	0.186	S	C	.	.	H	α-helix	trans	-88.8	-28.4	-173.1	-64.7	175.6	0	0	0	114.1	W60 L259 G384 P385 P391 L392	W60-L388 HydrophobicContact CH2-CD2 4.04Å; L259-L388 HydrophobicContact CD1-CB 4.44Å; G384-L388 WeakPolarHBondContact O-CG 3.26Å; G384-L388 PolarHBondContact O-N 3.43Å; G384-L388 VanDerWaalsContact O-N 3.08Å; P385-L388 PolarHBondContact O-N 2.99Å; L388-P391 WeakPolarHBondContact O-CD 3.39Å; L388-L392 HydrophobicContact CB-CD1 4.08Å; L388-L392 WeakPolarHBondContact O-CB 3.3Å; L388-L392 WeakPolarHBondContact O-CG 3.32Å; L388-L392 PolarHBondContact O-N 2.85Å
389	G	95.5	Very high	93.9	Very high	2 Å²	2	38.9 Å²	38.9	2%	0.021	22%	0.217	C	C	.	.	H	α-helix	trans	-57.4	-62.3	-171.3	0	0	0	0	0	113.4	L259 P385 L392 A393	L259-G389 WeakPolarHBondContact O-CA 3.22Å; P385-G389 WeakPolarHBondContact O-CA 3.47Å; P385-G389 PolarHBondContact O-N 3.13Å; G389-L392 PolarHBondContact O-N 3.44Å; G389-A393 VanDerWaalsContact O-CB 3.3Å; G389-A393 WeakPolarHBondContact O-CB 3.35Å; G389-A393 PolarHBondContact O-N 3.21Å
390	P	95.3	Very high	94.2	Very high	1 Å²	1	40.6 Å²	40.6	1%	0.006	23%	0.227	C	C	.	.	H	α-helix	trans	-60.6	-41.5	-179.7	-22.4	32.8	0	0	0	115.1	A59 S63 F262 A263 I266 F267 V386 A393 G394	A59-P390 HydrophobicContact CB-CB 4.05Å; S63-P390 VanDerWaalsContact OG-CB 3.28Å; S63-P390 WeakPolarHBondContact OG-CB 3.26Å; S63-P390 WeakPolarHBondContact OG-CD 3.5Å; S63-P390 WeakPolarHBondContact OG-CG 3.49Å; F262-P390 HydrophobicContact CB-CG 4.46Å; A263-P390 HydrophobicContact CB-CB 4.38Å; A263-P390 HydrophobicContact CB-CG 4.41Å; I266-P390 HydrophobicContact CD1-CB 3.85Å; I266-P390 HydrophobicContact CD1-CG 3.48Å; I266-P390 VanDerWaalsContact CD1-CG 3.48Å; F267-P390 WeakPolarHBondContact CE2-O 3.21Å; V386-P390 WeakPolarHBondContact O-CD 3.4Å; P390-A393 PolarHBondContact O-N 3Å; P390-G394 PolarHBondContact O-N 3.35Å
391	P	96.1	Very high	94.2	Very high	4 Å²	4	40.3 Å²	40.3	3%	0.026	24%	0.238	C	C	.	.	H	α-helix	trans	-64	-41	174.7	-26.7	35.4	0	0	0	113.5	S56 A59 W60 S63 L387 L388 A393 G394 K395	S56-P391 PolarHBondContact OG-O 3.48Å; A59-P391 HydrophobicContact CB-CG 4.46Å; W60-P391 HydrophobicContact CB-CG 4.46Å; W60-P391 HydrophobicContact CD2-CB 3.93Å; W60-P391 HydrophobicContact CD2-CG 3.48Å; W60-P391 VanDerWaalsContact CD2-CG 3.48Å; W60-P391 HydrophobicContact CE3-CG 3.9Å; W60-P391 HydrophobicContact CG-CB 4.13Å; W60-P391 HydrophobicContact CG-CG 3.75Å; W60-P391 HydrophobicContact CH2-CG 4.47Å; W60-P391 HydrophobicContact CZ2-CB 3.93Å; W60-P391 HydrophobicContact CZ2-CG 4.11Å; W60-P391 HydrophobicContact CZ3-CG 4.38Å; S63-P391 VanDerWaalsContact OG-CD 3.27Å; S63-P391 WeakPolarHBondContact OG-CD 3.43Å; L387-P391 WeakPolarHBondContact O-CD 3.47Å; L387-P391 WeakPolarHBondContact O-CG 3.48Å; L388-P391 WeakPolarHBondContact O-CD 3.39Å; P391-A393 VanDerWaalsContact C-N 3.33Å; P391-G394 PolarHBondContact O-N 3.32Å; P391-K395 WeakPolarHBondContact O-CB 3.47Å; P391-K395 PolarHBondContact O-N 3.31Å
392	L	96	Very high	94.1	Very high	98 Å²	98	39.7 Å²	39.7	51%	0.513	23%	0.232	S	C	.	.	H	α-helix	trans	-65.3	-39.4	175.3	-70.3	174	0	0	0	111.6	L388 G389 K395 L396	L388-L392 HydrophobicContact CB-CD1 4.08Å; L388-L392 WeakPolarHBondContact O-CB 3.3Å; L388-L392 WeakPolarHBondContact O-CG 3.32Å; L388-L392 PolarHBondContact O-N 2.85Å; G389-L392 PolarHBondContact O-N 3.44Å; L392-K395 PolarHBondContact O-N 3.16Å; L392-L396 PolarHBondContact O-N 3.46Å; L392-L396 VanDerWaalsContact O-N 3.14Å
393	A	95.1	Very high	94.2	Very high	10 Å²	10	39.6 Å²	39.6	8%	0.083	23%	0.232	C	C	.	.	H	α-helix	trans	-64.9	-43.4	174.4	0	0	0	0	0	111.9	A263 F267 G389 P390 P391 L396 V397 M406	A263-A393 HydrophobicContact CB-CB 3.49Å; A263-A393 VanDerWaalsContact CB-CB 3.49Å; F267-A393 HydrophobicContact CE2-CB 4.24Å; G389-A393 VanDerWaalsContact O-CB 3.3Å; G389-A393 WeakPolarHBondContact O-CB 3.35Å; G389-A393 PolarHBondContact O-N 3.21Å; P390-A393 PolarHBondContact O-N 3Å; P391-A393 VanDerWaalsContact C-N 3.33Å; A393-L396 WeakPolarHBondContact O-CB 3.43Å; A393-L396 PolarHBondContact O-N 3.05Å; A393-V397 PolarHBondContact O-N 3.11Å; A393-M406 HydrophobicContact CB-CG 3.72Å; A393-M406 HydrophobicContact CB-SD 4.3Å; A393-M406 WeakPolarHBondContact O-CG 3.12Å
394	G	94.1	Very high	94.2	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-63	-42.7	175	0	0	0	0	0	112.2	P390 P391 L396 V397 D398	P390-G394 PolarHBondContact O-N 3.35Å; P391-G394 PolarHBondContact O-N 3.32Å; G394-L396 PolarHBondContact O-N 2.9Å; G394-V397 CarbonylContact O-C 3.59Å; G394-V397 WeakPolarHBondContact O-CA 3.48Å; G394-V397 WeakPolarHBondContact O-CB 3.32Å; G394-V397 PolarHBondContact O-N 3.19Å; G394-D398 PolarHBondContact O-N 3.27Å
395	K	95.6	Very high	94.2	Very high	115 Å²	115	46.6 Å²	46.6	50%	0.5	25%	0.248	S	C	.	.	H	α-helix	trans	-59.8	-34.6	175.2	-173.9	177.4	-179.2	178.9	0	112.2	P391 L392 V397 D398 I399	P391-K395 WeakPolarHBondContact O-CB 3.47Å; P391-K395 PolarHBondContact O-N 3.31Å; L392-K395 PolarHBondContact O-N 3.16Å; K395-V397 VanDerWaalsContact C-N 3.32Å; K395-D398 WeakPolarHBondContact CA-OD2 3.46Å; K395-D398 PolarHBondContact O-N 3.16Å; K395-I399 HydrophobicContact CG-CD1 4.03Å; K395-I399 VanDerWaalsContact O-CG1 3.31Å; K395-I399 WeakPolarHBondContact O-CG1 2.95Å; K395-I399 PolarHBondContact O-N 3.35Å
396	L	95.3	Very high	94.2	Very high	56 Å²	56	46 Å²	46	29%	0.293	24%	0.244	S	C	.	.	H	α-helix	trans	-65.1	-38.9	174.5	-173.7	60.9	0	0	0	111.3	L392 A393 G394 T400 A409	L392-L396 PolarHBondContact O-N 3.46Å; L392-L396 VanDerWaalsContact O-N 3.14Å; A393-L396 WeakPolarHBondContact O-CB 3.43Å; A393-L396 PolarHBondContact O-N 3.05Å; G394-L396 PolarHBondContact O-N 2.9Å; L396-T400 HydrophobicContact CD1-CG2 4.07Å; L396-T400 WeakPolarHBondContact O-CB 3.25Å; L396-T400 WeakPolarHBondContact O-CG2 3.35Å; L396-T400 PolarHBondContact O-N 3.27Å; L396-T400 PolarHBondContact O-OG1 3.44Å; L396-A409 HydrophobicContact CD2-CB 3.64Å
397	V	93.3	Very high	94.3	Very high	1 Å²	1	45.9 Å²	45.9	1%	0.006	24%	0.243	C	C	.	.	H	α-helix	trans	-65.9	-43	172.3	-173.6	0	0	0	0	110.8	Y55 A393 G394 K395 I399 T400 G401 Y403 M406	Y55-V397 HydrophobicContact CD2-CB 4.15Å; Y55-V397 HydrophobicContact CD2-CG1 3.69Å; Y55-V397 HydrophobicContact CE2-CG1 3.85Å; Y55-V397 HydrophobicContact CG-CG1 4.3Å; A393-V397 PolarHBondContact O-N 3.11Å; G394-V397 CarbonylContact O-C 3.59Å; G394-V397 WeakPolarHBondContact O-CA 3.48Å; G394-V397 WeakPolarHBondContact O-CB 3.32Å; G394-V397 PolarHBondContact O-N 3.19Å; K395-V397 VanDerWaalsContact C-N 3.32Å; V397-I399 VanDerWaalsContact C-N 3.27Å; V397-I399 PolarHBondContact O-N 3.01Å; V397-T400 PolarHBondContact O-N 3.44Å; V397-G401 WeakPolarHBondContact O-CA 3.34Å; V397-G401 PolarHBondContact O-N 3.01Å; V397-Y403 HydrophobicContact CG1-CD1 4.23Å; V397-Y403 HydrophobicContact CG1-CD2 4.09Å; V397-Y403 HydrophobicContact CG1-CE1 4.26Å; V397-Y403 HydrophobicContact CG1-CE2 4.1Å; V397-Y403 HydrophobicContact CG1-CG 4.16Å; V397-Y403 HydrophobicContact CG2-CD1 3.93Å; V397-Y403 HydrophobicContact CG2-CE1 4.29Å; V397-Y403 HydrophobicContact CG2-CG 4.36Å; V397-M406 HydrophobicContact CG2-CB 3.47Å; V397-M406 VanDerWaalsContact CG2-CB 3.47Å; V397-M406 HydrophobicContact CG2-CG 3.89Å
398	D	92.9	Very high	94.3	Very high	55 Å²	55	48 Å²	48	29%	0.294	25%	0.253	S	S	.	.	H	α-helix	trans	-58.7	-37.9	178.7	-65.7	-45.4	0	0	0	112.7	T54 Y55 S56 G394 K395	T54-D398 WeakPolarHBondContact CB-OD1 3.17Å; Y55-D398 VanDerWaalsContact CB-OD1 3.31Å; Y55-D398 WeakPolarHBondContact CB-OD1 3.4Å; Y55-D398 WeakPolarHBondContact CD2-OD1 3.25Å; Y55-D398 PolarHBondContact N-OD1 3.31Å; Y55-D398 PolarHBondContact N-OD2 2.79Å; S56-D398 WeakPolarHBondContact CB-OD2 3.4Å; S56-D398 PolarHBondContact N-OD2 2.81Å; G394-D398 PolarHBondContact O-N 3.27Å; K395-D398 WeakPolarHBondContact CA-OD2 3.46Å; K395-D398 PolarHBondContact O-N 3.16Å
399	I	94.6	Very high	94.4	Very high	128 Å²	128	45.9 Å²	45.9	66%	0.656	25%	0.247	S	C	*	.	H	α-helix	trans	-80	-41	-179.3	-65.4	166.2	0	0	0	111.7	K395 V397	K395-I399 HydrophobicContact CG-CD1 4.03Å; K395-I399 VanDerWaalsContact O-CG1 3.31Å; K395-I399 WeakPolarHBondContact O-CG1 2.95Å; K395-I399 PolarHBondContact O-N 3.35Å; V397-I399 VanDerWaalsContact C-N 3.27Å; V397-I399 PolarHBondContact O-N 3.01Å
400	T	93.7	Very high	94.4	Very high	57 Å²	57	46 Å²	46	35%	0.35	25%	0.248	S	C	.	.	H	α-helix	trans	-89.7	-23.3	-172.8	58.1	0	0	0	0	113.5	L396 V397 D402 Y405	L396-T400 HydrophobicContact CD1-CG2 4.07Å; L396-T400 WeakPolarHBondContact O-CB 3.25Å; L396-T400 WeakPolarHBondContact O-CG2 3.35Å; L396-T400 PolarHBondContact O-N 3.27Å; L396-T400 PolarHBondContact O-OG1 3.44Å; V397-T400 PolarHBondContact O-N 3.44Å; T400-D402 PolarHBondContact O-N 3.24Å; T400-D402 PolarHBondContact OG1-O 2.9Å; T400-Y405 HydrophobicContact CG2-CD2 3.99Å; T400-Y405 HydrophobicContact CG2-CG 4.28Å
401	G	88.9	Confident	94.5	Very high	60 Å²	60	46 Å²	46	62%	0.619	25%	0.247	S	C	*	.	S	Bend	trans	75.6	-1.3	-174.3	0	0	0	0	0	115.1	V397	V397-G401 WeakPolarHBondContact O-CA 3.34Å; V397-G401 PolarHBondContact O-N 3.01Å
402	D	90.5	Very high	94.6	Very high	41 Å²	41	48.3 Å²	48.3	22%	0.219	27%	0.267	C	S	.	.			trans	-134.3	128.7	-177.4	-165.9	-26.5	0	0	0	111.6	T400 K404 Y405	T400-D402 PolarHBondContact O-N 3.24Å; T400-D402 PolarHBondContact OG1-O 2.9Å; D402-K404 PolarHBondContact O-N 3.17Å; D402-K404 WeakPolarHBondContact OD1-CB 3.14Å; D402-K404 WeakPolarHBondContact OD1-CG 3.35Å; D402-K404 PolarHBondContact OD1-N 3.1Å; D402-K404 WeakPolarHBondContact OD2-CD 3.33Å; D402-K404 WeakPolarHBondContact OD2-CE 3.28Å; D402-K404 IonicContact OD2-NZ 2.85Å; D402-K404 PolarHBondContact OD2-NZ 3.25Å; D402-Y405 HydrophobicContact CB-CD2 4.15Å; D402-Y405 HydrophobicContact CB-CE2 4.26Å; D402-Y405 PolarHBondContact O-N 3.23Å
403	Y	92.4	Very high	94.7	Very high	2 Å²	2	46.2 Å²	46.2	1%	0.008	26%	0.256	C	S	.	.	H	α-helix	trans	-61.2	-22.2	175.6	-75.6	-89.8	0	0	0	113.9	Y55 F267 P270 Y271 D274 V397 Y405 M406 Y407	Y55-Y403 VanDerWaalsContact CD1-OH 3.29Å; Y55-Y403 WeakPolarHBondContact CD1-OH 3.35Å; Y55-Y403 HydrophobicContact CE1-CE2 4.34Å; Y55-Y403 AromaticContact CE1-CZ 3.84Å; Y55-Y403 WeakPolarHBondContact CE1-OH 3.32Å; F267-Y403 HydrophobicContact CB-CD1 4.3Å; F267-Y403 HydrophobicContact CB-CE1 4.01Å; F267-Y403 AromaticContact CD1-CE1 3.89Å; F267-Y403 HydrophobicContact CD1-CE1 3.89Å; F267-Y403 HydrophobicContact CG-CE1 4.17Å; P270-Y403 WeakPolarHBondContact CB-OH 3.39Å; Y271-Y403 HydrophobicContact CD2-CD1 4.29Å; Y271-Y403 AromaticContact CD2-CD2 3.79Å; Y271-Y403 HydrophobicContact CD2-CD2 3.79Å; Y271-Y403 AromaticContact CD2-CG 3.54Å; Y271-Y403 HydrophobicContact CD2-CG 3.54Å; Y271-Y403 HydrophobicContact CE2-CG 4.3Å; Y271-Y403 HydrophobicContact CG-CG 4.23Å; D274-Y403 HydrophobicContact CB-CD2 4.28Å; D274-Y403 HydrophobicContact CB-CE2 3.85Å; V397-Y403 HydrophobicContact CG1-CD1 4.23Å; V397-Y403 HydrophobicContact CG1-CD2 4.09Å; V397-Y403 HydrophobicContact CG1-CE1 4.26Å; V397-Y403 HydrophobicContact CG1-CE2 4.1Å; V397-Y403 HydrophobicContact CG1-CG 4.16Å; V397-Y403 HydrophobicContact CG2-CD1 3.93Å; V397-Y403 HydrophobicContact CG2-CE1 4.29Å; V397-Y403 HydrophobicContact CG2-CG 4.36Å; Y403-Y405 VanDerWaalsContact C-N 3.29Å; Y403-Y405 PolarHBondContact O-N 3.28Å; Y403-M406 HydrophobicContact CD1-CE 3.82Å; Y403-M406 WeakPolarHBondContact O-CA 3.35Å; Y403-M406 WeakPolarHBondContact O-CB 3.21Å; Y403-M406 PolarHBondContact O-N 3.34Å; Y403-Y407 WeakPolarHBondContact O-CD2 3.19Å; Y403-Y407 PolarHBondContact O-N 3.43Å
404	K	92.8	Very high	94.8	Very high	74 Å²	74	45.8 Å²	45.8	32%	0.322	25%	0.252	S	S	.	.	H	α-helix	trans	-54.9	-45.1	179.4	-69.7	174.3	-160.8	137.4	0	111.9	P332 D402 M406 Y407 M408	P332-K404 HydrophobicContact CB-CB 3.99Å; P332-K404 HydrophobicContact CB-CD 4.39Å; P332-K404 HydrophobicContact CB-CG 3.83Å; P332-K404 HydrophobicContact CG-CB 4.28Å; D402-K404 PolarHBondContact O-N 3.17Å; D402-K404 WeakPolarHBondContact OD1-CB 3.14Å; D402-K404 WeakPolarHBondContact OD1-CG 3.35Å; D402-K404 PolarHBondContact OD1-N 3.1Å; D402-K404 WeakPolarHBondContact OD2-CD 3.33Å; D402-K404 WeakPolarHBondContact OD2-CE 3.28Å; D402-K404 IonicContact OD2-NZ 2.85Å; D402-K404 PolarHBondContact OD2-NZ 3.25Å; K404-M406 VanDerWaalsContact C-N 3.28Å; K404-M406 PolarHBondContact O-N 3.12Å; K404-Y407 PolarHBondContact O-N 3Å; K404-M408 VanDerWaalsContact O-CG 3.29Å; K404-M408 WeakPolarHBondContact O-CG 3.28Å; K404-M408 PolarHBondContact O-N 3.1Å
405	Y	94.4	Very high	95	Very high	129 Å²	129	47.2 Å²	47.2	51%	0.506	26%	0.261	S	S	.	.	H	α-helix	trans	-65.7	-33.2	179.2	-62	-68.3	0	0	0	112.2	T400 D402 Y403 A409	T400-Y405 HydrophobicContact CG2-CD2 3.99Å; T400-Y405 HydrophobicContact CG2-CG 4.28Å; D402-Y405 HydrophobicContact CB-CD2 4.15Å; D402-Y405 HydrophobicContact CB-CE2 4.26Å; D402-Y405 PolarHBondContact O-N 3.23Å; Y403-Y405 VanDerWaalsContact C-N 3.29Å; Y403-Y405 PolarHBondContact O-N 3.28Å; Y405-A409 WeakPolarHBondContact O-CB 3.32Å; Y405-A409 PolarHBondContact O-N 3Å
406	M	95.8	Very high	95.1	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-64.9	-47.8	173.8	180	-79	-66.3	0	0	111.9	A263 F267 A393 V397 Y403 K404 M408 A409 C410	A263-M406 HydrophobicContact CB-SD 4.45Å; F267-M406 HydrophobicContact CB-CE 3.63Å; F267-M406 HydrophobicContact CD2-CE 3.98Å; F267-M406 HydrophobicContact CD2-SD 4.28Å; F267-M406 HydrophobicContact CG-CE 4.08Å; A393-M406 HydrophobicContact CB-CG 3.72Å; A393-M406 HydrophobicContact CB-SD 4.3Å; A393-M406 WeakPolarHBondContact O-CG 3.12Å; V397-M406 HydrophobicContact CG2-CB 3.47Å; V397-M406 VanDerWaalsContact CG2-CB 3.47Å; V397-M406 HydrophobicContact CG2-CG 3.89Å; Y403-M406 HydrophobicContact CD1-CE 3.82Å; Y403-M406 WeakPolarHBondContact O-CA 3.35Å; Y403-M406 WeakPolarHBondContact O-CB 3.21Å; Y403-M406 PolarHBondContact O-N 3.34Å; K404-M406 VanDerWaalsContact C-N 3.28Å; K404-M406 PolarHBondContact O-N 3.12Å; M406-M408 PolarHBondContact O-N 3.34Å; M406-A409 PolarHBondContact O-N 3.29Å; M406-C410 WeakPolarHBondContact O-CB 3.45Å; M406-C410 PolarHBondContact O-N 2.93Å; M406-C410 PolarHBondContact O-SG 3.35Å
407	Y	96.1	Very high	95.2	Very high	0 Å²	0	41.6 Å²	41.6	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-64.5	-39	176.2	-79.5	-74.8	0	0	0	112.4	P264 L268 Y271 C331 Y343 Y403 K404 G411	P264-Y407 HydrophobicContact CB-CD1 4.05Å; P264-Y407 HydrophobicContact CB-CE1 3.66Å; P264-Y407 HydrophobicContact CG-CD1 4.36Å; P264-Y407 HydrophobicContact CG-CE1 4.41Å; P264-Y407 PolarHBondContact O-OH 3.47Å; L268-Y407 WeakPolarHBondContact CA-OH 3.36Å; Y271-Y407 AromaticContact CD1-CE2 3.62Å; Y271-Y407 HydrophobicContact CD1-CE2 3.62Å; Y271-Y407 HydrophobicContact CD2-CE2 4.32Å; Y271-Y407 HydrophobicContact CE1-CD2 4.49Å; Y271-Y407 AromaticContact CE1-CE2 3.95Å; Y271-Y407 HydrophobicContact CE1-CE2 3.95Å; Y271-Y407 AromaticContact CG-CE2 3.8Å; Y271-Y407 HydrophobicContact CG-CE2 3.8Å; C331-Y407 HydrophobicContact CB-CD1 3.99Å; C331-Y407 HydrophobicContact CB-CE1 4.47Å; C331-Y407 HydrophobicContact CB-CG 4.08Å; Y343-Y407 WeakPolarHBondContact OH-CE1 3.31Å; Y403-Y407 WeakPolarHBondContact O-CD2 3.19Å; Y403-Y407 PolarHBondContact O-N 3.43Å; K404-Y407 PolarHBondContact O-N 3Å; Y407-G411 PolarHBondContact O-N 3.11Å
408	M	96.4	Very high	95.4	Very high	95 Å²	95	41.6 Å²	41.6	47%	0.468	24%	0.243	S	C	.	.	H	α-helix	trans	-62	-46.6	174.7	-71.5	-179.9	74.4	0	0	111.8	L329 P332 K404 M406 G411 A412	L329-M408 WeakPolarHBondContact CD2-O 3.38Å; P332-M408 HydrophobicContact CG-CG 3.87Å; K404-M408 VanDerWaalsContact O-CG 3.29Å; K404-M408 WeakPolarHBondContact O-CG 3.28Å; K404-M408 PolarHBondContact O-N 3.1Å; M406-M408 PolarHBondContact O-N 3.34Å; M408-G411 PolarHBondContact O-N 2.91Å; M408-A412 VanDerWaalsContact O-CB 3.27Å; M408-A412 WeakPolarHBondContact O-CB 3.44Å; M408-A412 PolarHBondContact O-N 3.35Å
409	A	97	Very high	95.7	Very high	36 Å²	36	41.8 Å²	41.8	30%	0.298	25%	0.246	S	C	.	.	H	α-helix	trans	-64.5	-45.7	178.2	0	0	0	0	0	111.9	L396 Y405 M406 A412 I413	L396-A409 HydrophobicContact CD2-CB 3.64Å; Y405-A409 WeakPolarHBondContact O-CB 3.32Å; Y405-A409 PolarHBondContact O-N 3Å; M406-A409 PolarHBondContact O-N 3.29Å; A409-A412 PolarHBondContact O-N 3.33Å; A409-I413 VanDerWaalsContact O-CG1 3.3Å; A409-I413 WeakPolarHBondContact O-CG1 3.49Å; A409-I413 PolarHBondContact O-N 3.36Å
410	C	97	Very high	95.8	Very high	5 Å²	5	41.3 Å²	41.3	3%	0.034	24%	0.237	C	C	.	.	H	α-helix	trans	-61.8	-46.2	177	-67.7	0	0	0	0	111.4	P264 M406 A412 I413 V414	P264-C410 HydrophobicContact CG-CB 3.74Å; M406-C410 WeakPolarHBondContact O-CB 3.45Å; M406-C410 PolarHBondContact O-N 2.93Å; M406-C410 PolarHBondContact O-SG 3.35Å; C410-A412 PolarHBondContact O-N 3.11Å; C410-I413 PolarHBondContact O-N 3.04Å; C410-V414 VanDerWaalsContact O-CG2 3.27Å; C410-V414 WeakPolarHBondContact O-CG2 3.25Å; C410-V414 PolarHBondContact O-N 2.9Å
411	G	97.2	Very high	95.8	Very high	0 Å²	0	38.7 Å²	38.7	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-60.6	-44.1	176.2	0	0	0	0	0	112.6	G325 Y407 M408 I413 V414 V415	G325-G411 WeakPolarHBondContact O-CA 3.33Å; Y407-G411 PolarHBondContact O-N 3.11Å; M408-G411 PolarHBondContact O-N 2.91Å; G411-I413 PolarHBondContact O-N 3.15Å; G411-V414 PolarHBondContact O-N 2.95Å; G411-V415 WeakPolarHBondContact O-CB 3.26Å; G411-V415 WeakPolarHBondContact O-CG2 3.43Å; G411-V415 PolarHBondContact O-N 2.72Å
412	A	97.9	Very high	96.1	Very high	52 Å²	52	38.5 Å²	38.5	43%	0.43	21%	0.205	S	C	.	.	H	α-helix	trans	-62.3	-42.5	177.2	0	0	0	0	0	112.4	M408 A409 C410 V415 A416	M408-A412 VanDerWaalsContact O-CB 3.27Å; M408-A412 WeakPolarHBondContact O-CB 3.44Å; M408-A412 PolarHBondContact O-N 3.35Å; A409-A412 PolarHBondContact O-N 3.33Å; C410-A412 PolarHBondContact O-N 3.11Å; A412-V415 PolarHBondContact O-N 3.18Å; A412-A416 VanDerWaalsContact O-CB 3.3Å; A412-A416 WeakPolarHBondContact O-CB 3.02Å; A412-A416 PolarHBondContact O-N 3.08Å
413	I	97.7	Very high	96.3	Very high	55 Å²	55	41 Å²	41	28%	0.282	22%	0.217	S	C	.	.	H	α-helix	trans	-63.5	-44.3	176.3	-70.7	166.6	0	0	0	111	I256 L259 A409 C410 G411 A416 A417	I256-I413 HydrophobicContact CG2-CG2 4.18Å; I256-I413 WeakPolarHBondContact O-CG2 3.38Å; L259-I413 HydrophobicContact CB-CG2 4.33Å; L259-I413 HydrophobicContact CD2-CD1 4.33Å; A409-I413 VanDerWaalsContact O-CG1 3.3Å; A409-I413 WeakPolarHBondContact O-CG1 3.49Å; A409-I413 PolarHBondContact O-N 3.36Å; C410-I413 PolarHBondContact O-N 3.04Å; G411-I413 PolarHBondContact O-N 3.15Å; I413-A416 PolarHBondContact O-N 2.84Å; I413-A417 WeakPolarHBondContact O-CB 3.25Å; I413-A417 PolarHBondContact O-N 2.79Å
414	V	97.9	Very high	96.3	Very high	0 Å²	0	41.2 Å²	41.2	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-66.7	-40.8	179.3	174.7	0	0	0	0	111.1	I321 C410 G411 A417 S418	I321-V414 HydrophobicContact CG2-CG1 3.63Å; I321-V414 WeakPolarHBondContact O-CG1 3.36Å; C410-V414 VanDerWaalsContact O-CG2 3.27Å; C410-V414 WeakPolarHBondContact O-CG2 3.25Å; C410-V414 PolarHBondContact O-N 2.9Å; G411-V414 PolarHBondContact O-N 2.95Å; V414-A417 PolarHBondContact O-N 2.92Å; V414-S418 PolarHBondContact O-N 3.05Å
415	V	98.1	Very high	96.2	Very high	31 Å²	31	37.9 Å²	37.9	19%	0.188	21%	0.206	C	C	.	.	H	α-helix	trans	-62.9	-45.7	172.7	168.6	0	0	0	0	110.7	M322 V326 L329 G411 A412 A417 S418 V419	M322-V415 HydrophobicContact CE-CG1 4.35Å; M322-V415 HydrophobicContact SD-CB 4.36Å; M322-V415 HydrophobicContact SD-CG1 3.79Å; M322-V415 HydrophobicContact SD-CG2 4.09Å; V326-V415 HydrophobicContact CG2-CG2 4.28Å; L329-V415 HydrophobicContact CD1-CG2 4.05Å; G411-V415 WeakPolarHBondContact O-CB 3.26Å; G411-V415 WeakPolarHBondContact O-CG2 3.43Å; G411-V415 PolarHBondContact O-N 2.72Å; A412-V415 PolarHBondContact O-N 3.18Å; V415-A417 VanDerWaalsContact C-N 3.31Å; V415-A417 PolarHBondContact O-N 2.96Å; V415-S418 WeakPolarHBondContact O-CB 3.28Å; V415-S418 PolarHBondContact O-N 3.22Å; V415-S418 VanDerWaalsContact O-N 3.07Å; V415-S418 PolarHBondContact O-OG 3.34Å; V415-V419 HydrophobicContact CG1-CG2 4.46Å; V415-V419 WeakPolarHBondContact O-CG2 3.35Å; V415-V419 PolarHBondContact O-N 3.11Å
416	A	98	Very high	96.1	Very high	53 Å²	53	33.1 Å²	33.1	44%	0.438	19%	0.193	S	C	.	.	H	α-helix	trans	-59.1	-42	176.6	0	0	0	0	0	112	A412 I413 S418 V419 W420	A412-A416 VanDerWaalsContact O-CB 3.3Å; A412-A416 WeakPolarHBondContact O-CB 3.02Å; A412-A416 PolarHBondContact O-N 3.08Å; I413-A416 PolarHBondContact O-N 2.84Å; A416-S418 VanDerWaalsContact C-N 3.32Å; A416-S418 PolarHBondContact O-N 3Å; A416-V419 PolarHBondContact O-N 3.48Å; A416-W420 WeakPolarHBondContact O-CB 3.39Å; A416-W420 PolarHBondContact O-N 2.97Å
417	A	97.5	Very high	95.8	Very high	0 Å²	0	37.5 Å²	37.5	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-61.2	-40.5	174	0	0	0	0	0	112.2	I256 M257 I413 V414 V415 W420 L421	I256-A417 HydrophobicContact CB-CB 3.99Å; I256-A417 HydrophobicContact CG2-CB 3.82Å; M257-A417 HydrophobicContact CB-CB 3.78Å; I413-A417 WeakPolarHBondContact O-CB 3.25Å; I413-A417 PolarHBondContact O-N 2.79Å; V414-A417 PolarHBondContact O-N 2.92Å; V415-A417 VanDerWaalsContact C-N 3.31Å; V415-A417 PolarHBondContact O-N 2.96Å; A417-W420 PolarHBondContact O-N 3.08Å; A417-L421 WeakPolarHBondContact O-CB 3.43Å; A417-L421 WeakPolarHBondContact O-CG 3.12Å; A417-L421 PolarHBondContact O-N 3.27Å
418	S	97.5	Very high	95.5	Very high	0 Å²	0	38 Å²	38	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-65.6	-42.9	177.6	77.5	0	0	0	0	112.4	M322 V414 V415 A416 L421 L422	M322-S418 WeakPolarHBondContact CE-OG 3.28Å; M322-S418 PolarHBondContact SD-OG 3.01Å; M322-S418 VanDerWaalsContact SD-OG 3.38Å; V414-S418 PolarHBondContact O-N 3.05Å; V415-S418 WeakPolarHBondContact O-CB 3.28Å; V415-S418 PolarHBondContact O-N 3.22Å; V415-S418 VanDerWaalsContact O-N 3.07Å; V415-S418 PolarHBondContact O-OG 3.34Å; A416-S418 VanDerWaalsContact C-N 3.32Å; A416-S418 PolarHBondContact O-N 3Å; S418-L421 PolarHBondContact O-N 3.04Å; S418-L422 WeakPolarHBondContact O-CG 3.38Å; S418-L422 PolarHBondContact O-N 2.92Å
419	V	97.4	Very high	95.2	Very high	59 Å²	59	35.9 Å²	35.9	36%	0.358	21%	0.206	S	C	.	.	H	α-helix	trans	-64.3	-43.5	176.1	174.9	0	0	0	0	110.3	M322 V415 A416 L421 L422 I423	M322-V419 HydrophobicContact CE-CG2 3.68Å; V415-V419 HydrophobicContact CG1-CG2 4.46Å; V415-V419 WeakPolarHBondContact O-CG2 3.35Å; V415-V419 PolarHBondContact O-N 3.11Å; A416-V419 PolarHBondContact O-N 3.48Å; V419-L421 PolarHBondContact O-N 3.13Å; V419-L422 PolarHBondContact O-N 3.43Å; V419-I423 HydrophobicContact CG1-CD1 3.67Å; V419-I423 HydrophobicContact CG1-CG1 4.33Å; V419-I423 VanDerWaalsContact O-CG1 3.31Å; V419-I423 WeakPolarHBondContact O-CG1 3.4Å; V419-I423 PolarHBondContact O-N 2.9Å
420	W	96.9	Very high	94.8	Very high	119 Å²	119	43.7 Å²	43.7	45%	0.451	23%	0.227	S	C	.	.	H	α-helix	trans	-57.3	-48	174.5	173.9	-105.6	0	0	0	112	S252 I256 A416 A417 I423 G424	S252-W420 PolarHBondContact OG-NE1 3.01Å; I256-W420 HydrophobicContact CD1-CG 4.36Å; A416-W420 WeakPolarHBondContact O-CB 3.39Å; A416-W420 PolarHBondContact O-N 2.97Å; A417-W420 PolarHBondContact O-N 3.08Å; W420-I423 PolarHBondContact O-N 3.14Å; W420-G424 PolarHBondContact O-N 3.01Å
421	L	95.3	Very high	94.4	Very high	1 Å²	1	46.8 Å²	46.8	1%	0.005	24%	0.243	C	C	.	.	H	α-helix	trans	-65.2	-39.3	177.5	-74.7	171.4	0	0	0	112.2	I249 F317 S318 I321 A417 S418 V419 N425	I249-L421 HydrophobicContact CG2-CD2 4.41Å; I249-L421 WeakPolarHBondContact O-CD2 3.45Å; F317-L421 HydrophobicContact CD1-CD1 4.32Å; F317-L421 HydrophobicContact CE1-CD1 3.98Å; S318-L421 WeakPolarHBondContact OG-CB 3.4Å; I321-L421 HydrophobicContact CD1-CD1 3.48Å; I321-L421 VanDerWaalsContact CD1-CD1 3.48Å; A417-L421 WeakPolarHBondContact O-CB 3.43Å; A417-L421 WeakPolarHBondContact O-CG 3.12Å; A417-L421 PolarHBondContact O-N 3.27Å; S418-L421 PolarHBondContact O-N 3.04Å; V419-L421 PolarHBondContact O-N 3.13Å; L421-N425 WeakPolarHBondContact O-CB 3.38Å; L421-N425 PolarHBondContact O-N 2.79Å; L421-N425 PolarHBondContact O-ND2 2.77Å
422	L	94.9	Very high	93.9	Very high	57 Å²	57	49.4 Å²	49.4	30%	0.298	26%	0.257	S	S	.	.	H	α-helix	trans	-60.7	-50.1	175.6	-77.1	172.9	0	0	0	111.6	Y315 S318 M322 S418 V419 A426	Y315-L422 HydrophobicContact CD1-CD2 3.98Å; S318-L422 VanDerWaalsContact CB-CD2 3.43Å; M322-L422 HydrophobicContact CE-CD1 4.39Å; S418-L422 WeakPolarHBondContact O-CG 3.38Å; S418-L422 PolarHBondContact O-N 2.92Å; V419-L422 PolarHBondContact O-N 3.43Å; L422-A426 VanDerWaalsContact O-CB 3.26Å; L422-A426 WeakPolarHBondContact O-CB 3.46Å; L422-A426 PolarHBondContact O-N 2.94Å
423	I	94.4	Very high	93.4	Very high	93 Å²	93	49.2 Å²	49.2	48%	0.477	26%	0.255	S	S	.	.	H	α-helix	trans	-65.3	-48.6	-179.7	-65.9	170.6	0	0	0	110	V419 W420 N425 A426 I427	V419-I423 HydrophobicContact CG1-CD1 3.67Å; V419-I423 HydrophobicContact CG1-CG1 4.33Å; V419-I423 VanDerWaalsContact O-CG1 3.31Å; V419-I423 WeakPolarHBondContact O-CG1 3.4Å; V419-I423 PolarHBondContact O-N 2.9Å; W420-I423 PolarHBondContact O-N 3.14Å; I423-N425 PolarHBondContact O-N 3.39Å; I423-A426 PolarHBondContact O-N 2.86Å; I423-I427 HydrophobicContact CG2-CD1 3.86Å; I423-I427 WeakPolarHBondContact O-CG1 3.15Å; I423-I427 PolarHBondContact O-N 3.23Å
424	G	92	Very high	93	Very high	7 Å²	7	52.8 Å²	52.8	7%	0.072	27%	0.269	C	S	.	.	H	α-helix	trans	-58.6	-47.6	178.9	0	0	0	0	0	112	W420 A426 I427 N428	W420-G424 PolarHBondContact O-N 3.01Å; G424-A426 PolarHBondContact O-N 2.98Å; G424-I427 PolarHBondContact O-N 3.33Å; G424-N428 WeakPolarHBondContact O-CB 3.32Å; G424-N428 PolarHBondContact O-N 3.22Å
425	N	91.8	Very high	92.5	Very high	3 Å²	3	56.2 Å²	56.2	2%	0.016	29%	0.285	C	S	.	.	H	α-helix	trans	-65.2	-39	176.9	-70.4	-30.4	0	0	0	111.5	Q314 Y315 L421 I423 I427 N428 Y429	Q314-N425 PolarHBondContact O-ND2 2.91Å; Y315-N425 HydrophobicContact CE1-CB 4.36Å; L421-N425 WeakPolarHBondContact O-CB 3.38Å; L421-N425 PolarHBondContact O-N 2.79Å; L421-N425 PolarHBondContact O-ND2 2.77Å; I423-N425 PolarHBondContact O-N 3.39Å; N425-I427 PolarHBondContact O-N 2.94Å; N425-N428 PolarHBondContact O-N 2.89Å; N425-Y429 HydrophobicContact CB-CD2 4.48Å; N425-Y429 WeakPolarHBondContact O-CD2 3.22Å; N425-Y429 PolarHBondContact O-N 3.14Å
426	A	90.6	Very high	92	Very high	29 Å²	29	62.9 Å²	62.9	24%	0.24	31%	0.307	C	S	.	.	H	α-helix	trans	-61.2	-42.8	175	0	0	0	0	0	113	Y315 L422 I423 G424 R430	Y315-A426 HydrophobicContact CE1-CB 4.38Å; Y315-A426 WeakPolarHBondContact OH-CA 3.2Å; L422-A426 VanDerWaalsContact O-CB 3.26Å; L422-A426 WeakPolarHBondContact O-CB 3.46Å; L422-A426 PolarHBondContact O-N 2.94Å; I423-A426 PolarHBondContact O-N 2.86Å; G424-A426 PolarHBondContact O-N 2.98Å; A426-R430 VanDerWaalsContact O-CG 3.32Å; A426-R430 WeakPolarHBondContact O-CG 3.39Å; A426-R430 PolarHBondContact O-N 3.43Å; A426-R430 VanDerWaalsContact O-N 3.09Å
427	I	90.4	Very high	91.6	Very high	92 Å²	92	67.8 Å²	67.8	47%	0.472	32%	0.318	S	S	.	.	H	α-helix	trans	-63.2	-46.6	174	-65.9	166.7	0	0	0	109.9	I423 G424 N425 Y429 R430 L431	I423-I427 HydrophobicContact CG2-CD1 3.86Å; I423-I427 WeakPolarHBondContact O-CG1 3.15Å; I423-I427 PolarHBondContact O-N 3.23Å; G424-I427 PolarHBondContact O-N 3.33Å; N425-I427 PolarHBondContact O-N 2.94Å; I427-Y429 PolarHBondContact O-N 2.93Å; I427-R430 PolarHBondContact O-N 3.44Å; I427-L431 HydrophobicContact CG2-CD1 3.9Å; I427-L431 HydrophobicContact CG2-CG 4.35Å; I427-L431 WeakPolarHBondContact O-CG 3.34Å; I427-L431 PolarHBondContact O-N 3.08Å
428	N	90.5	Very high	91.2	Very high	12 Å²	12	72 Å²	72	6%	0.064	34%	0.337	C	S	.	.	H	α-helix	trans	-60.2	-45.5	-179.9	-170.7	47.5	0	0	0	112.1	I249 G424 N425 R430 L431 L432	I249-N428 HydrophobicContact CD1-CB 3.96Å; G424-N428 WeakPolarHBondContact O-CB 3.32Å; G424-N428 PolarHBondContact O-N 3.22Å; N425-N428 PolarHBondContact O-N 2.89Å; N428-R430 PolarHBondContact O-N 2.58Å; N428-L431 PolarHBondContact O-N 3.14Å; N428-L432 WeakPolarHBondContact O-CB 3.38Å; N428-L432 VanDerWaalsContact O-CG 3.26Å; N428-L432 WeakPolarHBondContact O-CG 3.49Å; N428-L432 PolarHBondContact O-N 2.74Å
429	Y	88.8	Confident	90.7	Very high	50 Å²	50	77.6 Å²	77.6	20%	0.196	36%	0.364	C	S	.	.	H	α-helix	trans	-63.4	-39.4	176.3	-82.5	-66.8	0	0	0	112.6	P311 Q314 Y315 N425 I427 A433	P311-Y429 PolarHBondContact O-OH 2.98Å; Q314-Y429 HydrophobicContact CB-CE2 4.26Å; Q314-Y429 PolarHBondContact OE1-OH 3.27Å; Y315-Y429 HydrophobicContact CD2-CD2 4.33Å; Y315-Y429 AromaticContact CD2-CE2 3.82Å; Y315-Y429 HydrophobicContact CD2-CE2 3.82Å; Y315-Y429 HydrophobicContact CE1-CD2 4.47Å; Y315-Y429 AromaticContact CE2-CD2 3.39Å; Y315-Y429 HydrophobicContact CE2-CD2 3.39Å; Y315-Y429 AromaticContact CE2-CE2 3.3Å; Y315-Y429 HydrophobicContact CE2-CE2 3.3Å; Y315-Y429 HydrophobicContact CE2-CG 4.32Å; Y315-Y429 AromaticContact CZ-CD2 3.48Å; Y315-Y429 VanDerWaalsContact CZ-CD2 3.48Å; Y315-Y429 AromaticContact CZ-CE2 3.8Å; Y315-Y429 VanDerWaalsContact OH-CD2 3.32Å; Y315-Y429 WeakPolarHBondContact OH-CD2 3.33Å; N425-Y429 HydrophobicContact CB-CD2 4.48Å; N425-Y429 WeakPolarHBondContact O-CD2 3.22Å; N425-Y429 PolarHBondContact O-N 3.14Å; I427-Y429 PolarHBondContact O-N 2.93Å; Y429-A433 WeakPolarHBondContact O-CB 3.46Å; Y429-A433 PolarHBondContact O-N 3.18Å
430	R	89.4	Confident	90.1	Very high	200 Å²	200	77.8 Å²	77.8	76%	0.755	37%	0.368	S	S	*	.	H	α-helix	trans	-64.2	-44.1	175.8	-75.1	177.8	-179.4	-168.2	1.7	111.8	A426 I427 N428 A433 K434	A426-R430 VanDerWaalsContact O-CG 3.32Å; A426-R430 WeakPolarHBondContact O-CG 3.39Å; A426-R430 PolarHBondContact O-N 3.43Å; A426-R430 VanDerWaalsContact O-N 3.09Å; I427-R430 PolarHBondContact O-N 3.44Å; N428-R430 PolarHBondContact O-N 2.58Å; R430-A433 PolarHBondContact O-N 3.36Å; R430-K434 PolarHBondContact O-N 3.39Å
431	L	87.5	Confident	89.6	Confident	69 Å²	69	74.6 Å²	74.6	36%	0.361	37%	0.367	S	S	.	.	H	α-helix	trans	-64.5	-45.7	177	-70.1	174.1	0	0	0	111.5	I427 N428 A433 K434 E435	I427-L431 HydrophobicContact CG2-CD1 3.9Å; I427-L431 HydrophobicContact CG2-CG 4.35Å; I427-L431 WeakPolarHBondContact O-CG 3.34Å; I427-L431 PolarHBondContact O-N 3.08Å; N428-L431 PolarHBondContact O-N 3.14Å; L431-A433 VanDerWaalsContact C-N 3.28Å; L431-A433 PolarHBondContact O-N 2.96Å; L431-K434 WeakPolarHBondContact O-CB 3.49Å; L431-K434 PolarHBondContact O-N 3.45Å; L431-K434 VanDerWaalsContact O-N 3.11Å; L431-E435 WeakPolarHBondContact O-CG 3.23Å; L431-E435 PolarHBondContact O-N 2.99Å
432	L	87.1	Confident	89.1	Confident	56 Å²	56	83 Å²	83	29%	0.293	40%	0.398	S	S	.	.	H	α-helix	trans	-61.1	-37.1	175.8	-73.6	169.7	0	0	0	112.2	N428 R436	N428-L432 WeakPolarHBondContact O-CB 3.38Å; N428-L432 VanDerWaalsContact O-CG 3.26Å; N428-L432 WeakPolarHBondContact O-CG 3.49Å; N428-L432 PolarHBondContact O-N 2.74Å; L432-R436 VanDerWaalsContact O-CG 3.32Å; L432-R436 WeakPolarHBondContact O-CG 3.41Å; L432-R436 PolarHBondContact O-N 2.96Å
433	A	87.2	Confident	88.6	Confident	48 Å²	48	87.4 Å²	87.4	40%	0.397	42%	0.415	S	S	.	.	H	α-helix	trans	-66.5	-39.7	174.8	0	0	0	0	0	111.8	Y429 R430 L431 K437	Y429-A433 WeakPolarHBondContact O-CB 3.46Å; Y429-A433 PolarHBondContact O-N 3.18Å; R430-A433 PolarHBondContact O-N 3.36Å; L431-A433 VanDerWaalsContact C-N 3.28Å; L431-A433 PolarHBondContact O-N 2.96Å; A433-K437 WeakPolarHBondContact O-CG 3.41Å; A433-K437 PolarHBondContact O-N 3.34Å; A433-K437 VanDerWaalsContact O-N 3.1Å
434	K	89.2	Confident	88.1	Confident	130 Å²	130	87 Å²	87	57%	0.565	42%	0.417	S	S	*	.	H	α-helix	trans	-63.9	-47.6	175.3	-168.8	-177.6	178.4	-174.5	0	111.5	R430 L431 R436 K437 E438	R430-K434 PolarHBondContact O-N 3.39Å; L431-K434 WeakPolarHBondContact O-CB 3.49Å; L431-K434 PolarHBondContact O-N 3.45Å; L431-K434 VanDerWaalsContact O-N 3.11Å; K434-R436 VanDerWaalsContact C-N 3.33Å; K434-R436 PolarHBondContact O-N 3.42Å; K434-K437 WeakPolarHBondContact O-CB 3.39Å; K434-K437 PolarHBondContact O-N 2.84Å; K434-K437 VanDerWaalsContact O-N 3.14Å; K434-E438 VanDerWaalsContact CE-OE1 3.23Å; K434-E438 WeakPolarHBondContact CE-OE1 3.16Å; K434-E438 WeakPolarHBondContact O-CG 3.43Å; K434-E438 PolarHBondContact O-N 3.18Å
435	E	88.6	Confident	87.7	Confident	71 Å²	71	90.4 Å²	90.4	33%	0.332	44%	0.436	S	S	.	.	H	α-helix	trans	-60.8	-39.9	177.9	-71.6	173	-177	0	0	112	R245 L431 E438 Q439	R245-E435 IonicContact CZ-OE1 3.79Å; R245-E435 IonicContact NH1-OE1 2.77Å; R245-E435 PolarHBondContact NH1-OE1 2.91Å; L431-E435 WeakPolarHBondContact O-CG 3.23Å; L431-E435 PolarHBondContact O-N 2.99Å; E435-E438 PolarHBondContact O-N 2.92Å; E435-Q439 WeakPolarHBondContact O-CB 3.31Å; E435-Q439 VanDerWaalsContact O-CG 3.31Å; E435-Q439 WeakPolarHBondContact O-CG 3.46Å; E435-Q439 PolarHBondContact O-N 2.88Å
436	R	87.4	Confident	87.2	Confident	172 Å²	172	98.6 Å²	98.6	65%	0.649	47%	0.467	S	S	*	.	H	α-helix	trans	-63.1	-43.6	174.1	-74.7	-178.5	-144.3	-156.7	4.5	112.2	L432 K434 Q439 S440	L432-R436 VanDerWaalsContact O-CG 3.32Å; L432-R436 WeakPolarHBondContact O-CG 3.41Å; L432-R436 PolarHBondContact O-N 2.96Å; K434-R436 VanDerWaalsContact C-N 3.33Å; K434-R436 PolarHBondContact O-N 3.42Å; R436-Q439 PolarHBondContact O-N 3.37Å; R436-S440 PolarHBondContact O-N 2.98Å; R436-S440 PolarHBondContact O-OG 2.81Å; R436-S440 VanDerWaalsContact O-OG 3.11Å
437	K	89.2	Confident	86.6	Confident	156 Å²	156	103.2 Å²	103.2	68%	0.678	48%	0.484	S	S	*	.	H	α-helix	trans	-61.9	-43.5	176.8	-74.8	-178.2	179.1	-171.5	0	111.7	A433 K434 S440 A441	A433-K437 WeakPolarHBondContact O-CG 3.41Å; A433-K437 PolarHBondContact O-N 3.34Å; A433-K437 VanDerWaalsContact O-N 3.1Å; K434-K437 WeakPolarHBondContact O-CB 3.39Å; K434-K437 PolarHBondContact O-N 2.84Å; K434-K437 VanDerWaalsContact O-N 3.14Å; K437-S440 WeakPolarHBondContact CA-OG 3.43Å; K437-S440 PolarHBondContact O-N 2.94Å; K437-S440 PolarHBondContact O-OG 3.47Å; K437-A441 WeakPolarHBondContact O-CB 3.11Å; K437-A441 PolarHBondContact O-N 3.05Å
438	E	89.3	Confident	85.9	Confident	87 Å²	87	102.1 Å²	102.1	41%	0.407	48%	0.484	S	S	.	.	H	α-helix	trans	-64.9	-39.4	176.8	-71.6	174.4	-170.3	0	0	112.1	K434 E435 A441 R442	K434-E438 VanDerWaalsContact CE-OE1 3.23Å; K434-E438 WeakPolarHBondContact CE-OE1 3.16Å; K434-E438 WeakPolarHBondContact O-CG 3.43Å; K434-E438 PolarHBondContact O-N 3.18Å; E435-E438 PolarHBondContact O-N 2.92Å; E438-A441 PolarHBondContact O-N 3.24Å; E438-R442 WeakPolarHBondContact O-CB 3.5Å; E438-R442 WeakPolarHBondContact O-CG 3.4Å; E438-R442 PolarHBondContact O-N 2.93Å
439	Q	86.1	Confident	85.3	Confident	119 Å²	119	106.6 Å²	106.6	56%	0.556	51%	0.505	S	S	*	.	H	α-helix	trans	-67.1	-41.4	175	-74.6	179.2	7.4	0	0	112.5	E435 R436 A441 R442 K443	E435-Q439 WeakPolarHBondContact O-CB 3.31Å; E435-Q439 VanDerWaalsContact O-CG 3.31Å; E435-Q439 WeakPolarHBondContact O-CG 3.46Å; E435-Q439 PolarHBondContact O-N 2.88Å; R436-Q439 PolarHBondContact O-N 3.37Å; Q439-A441 VanDerWaalsContact C-N 3.34Å; Q439-R442 PolarHBondContact O-N 3.38Å; Q439-K443 WeakPolarHBondContact O-CG 3.35Å; Q439-K443 PolarHBondContact O-N 3.26Å
440	S	85.2	Confident	84.7	Confident	62 Å²	62	113.7 Å²	113.7	43%	0.434	53%	0.531	S	S	.	.	H	α-helix	trans	-64.5	-39.9	174.1	50.6	0	0	0	0	111.7	R436 K437 K443 T444	R436-S440 PolarHBondContact O-N 2.98Å; R436-S440 PolarHBondContact O-OG 2.81Å; R436-S440 VanDerWaalsContact O-OG 3.11Å; K437-S440 WeakPolarHBondContact CA-OG 3.43Å; K437-S440 PolarHBondContact O-N 2.94Å; K437-S440 PolarHBondContact O-OG 3.47Å; S440-K443 PolarHBondContact O-N 3.19Å; S440-T444 WeakPolarHBondContact O-CB 3.47Å; S440-T444 PolarHBondContact O-N 3.48Å; S440-T444 PolarHBondContact O-OG1 3.16Å
441	A	86.3	Confident	83.9	Confident	52 Å²	52	109.1 Å²	109.1	43%	0.43	52%	0.521	S	S	.	.	H	α-helix	trans	-61.6	-49.7	175.1	0	0	0	0	0	110.9	K437 E438 Q439 K443 T444 T445	K437-A441 WeakPolarHBondContact O-CB 3.11Å; K437-A441 PolarHBondContact O-N 3.05Å; E438-A441 PolarHBondContact O-N 3.24Å; Q439-A441 VanDerWaalsContact C-N 3.34Å; A441-K443 VanDerWaalsContact C-N 3.32Å; A441-K443 PolarHBondContact O-N 3.07Å; A441-T444 PolarHBondContact O-N 2.77Å; A441-T445 PolarHBondContact O-N 3.46Å; A441-T445 PolarHBondContact O-OG1 3.42Å
442	R	85.4	Confident	83.1	Confident	177 Å²	177	109.1 Å²	109.1	67%	0.668	53%	0.527	S	S	*	.	H	α-helix	trans	-59.8	-37.4	176.6	-75	178.2	-179.3	-176.4	1.9	113.5	E438 Q439 R446	E438-R442 WeakPolarHBondContact O-CB 3.5Å; E438-R442 WeakPolarHBondContact O-CG 3.4Å; E438-R442 PolarHBondContact O-N 2.93Å; Q439-R442 PolarHBondContact O-N 3.38Å; R442-R446 WeakPolarHBondContact O-CB 3.44Å; R442-R446 WeakPolarHBondContact O-CG 3.36Å; R442-R446 PolarHBondContact O-N 3.44Å; R442-R446 VanDerWaalsContact O-N 3.07Å
443	K	83.8	Confident	82.4	Confident	151 Å²	151	113.5 Å²	113.5	66%	0.657	54%	0.543	S	S	*	.	H	α-helix	trans	-65.7	-47	175	-78.6	-177.6	178	-175.2	0	111.2	Q439 S440 A441 T445 R446 E447	Q439-K443 WeakPolarHBondContact O-CG 3.35Å; Q439-K443 PolarHBondContact O-N 3.26Å; S440-K443 PolarHBondContact O-N 3.19Å; A441-K443 VanDerWaalsContact C-N 3.32Å; A441-K443 PolarHBondContact O-N 3.07Å; K443-T445 PolarHBondContact O-N 2.92Å; K443-R446 PolarHBondContact O-N 2.92Å; K443-E447 WeakPolarHBondContact O-CB 3.45Å; K443-E447 PolarHBondContact O-N 3.05Å
444	T	83.6	Confident	81.5	Confident	83 Å²	83	114 Å²	114	51%	0.509	54%	0.544	S	S	.	.	H	α-helix	trans	-60.9	-45.3	178.1	-48.2	0	0	0	0	110.8	S440 A441 R446 E447 S448	S440-T444 WeakPolarHBondContact O-CB 3.47Å; S440-T444 PolarHBondContact O-N 3.48Å; S440-T444 PolarHBondContact O-OG1 3.16Å; A441-T444 PolarHBondContact O-N 2.77Å; T444-R446 PolarHBondContact O-N 2.78Å; T444-E447 PolarHBondContact O-N 3.03Å; T444-S448 PolarHBondContact O-N 3.14Å; T444-S448 PolarHBondContact O-OG 2.93Å
445	T	84.1	Confident	80.2	Confident	79 Å²	79	114.5 Å²	114.5	49%	0.485	55%	0.546	S	S	.	.	H	α-helix	trans	-60.2	-45.6	175.9	-51.3	0	0	0	0	112	A441 K443 E447 S448 E449	A441-T445 PolarHBondContact O-N 3.46Å; A441-T445 PolarHBondContact O-OG1 3.42Å; K443-T445 PolarHBondContact O-N 2.92Å; T445-E447 VanDerWaalsContact C-N 3.31Å; T445-E447 PolarHBondContact O-N 3.38Å; T445-S448 PolarHBondContact O-N 2.89Å; T445-E449 WeakPolarHBondContact O-CG 3.45Å; T445-E449 PolarHBondContact O-N 2.91Å
446	R	80.7	Confident	78.8	Confident	176 Å²	176	117.4 Å²	117.4	66%	0.664	56%	0.56	S	S	*	*	H	α-helix	trans	-64.5	-33.8	177.2	-78.4	179	175.3	-173.6	-1.6	113.1	R442 K443 T444 R450	R442-R446 WeakPolarHBondContact O-CB 3.44Å; R442-R446 WeakPolarHBondContact O-CG 3.36Å; R442-R446 PolarHBondContact O-N 3.44Å; R442-R446 VanDerWaalsContact O-N 3.07Å; K443-R446 PolarHBondContact O-N 2.92Å; T444-R446 PolarHBondContact O-N 2.78Å; R446-R450 WeakPolarHBondContact O-CG 3.34Å; R446-R450 PolarHBondContact O-N 2.87Å; R446-R450 VanDerWaalsContact O-N 3.1Å
447	E	79.3	Confident	77.3	Confident	125 Å²	125	113 Å²	113	58%	0.584	56%	0.555	S	S	*	*	H	α-helix	trans	-71.8	-43.4	177.3	-165.1	166.8	-166.6	0	0	110.9	K443 T444 T445 E449 R450 L451	K443-E447 WeakPolarHBondContact O-CB 3.45Å; K443-E447 PolarHBondContact O-N 3.05Å; T444-E447 PolarHBondContact O-N 3.03Å; T445-E447 VanDerWaalsContact C-N 3.31Å; T445-E447 PolarHBondContact O-N 3.38Å; E447-E449 PolarHBondContact O-N 3.38Å; E447-R450 PolarHBondContact O-N 3.5Å; E447-L451 HydrophobicContact CG-CD1 4.39Å; E447-L451 WeakPolarHBondContact O-CG 3.39Å; E447-L451 PolarHBondContact O-N 3.1Å
448	S	76.4	Confident	75.8	Confident	69 Å²	69	111.3 Å²	111.3	48%	0.483	55%	0.55	S	S	.	.	H	α-helix	trans	-60.8	-41.3	171.9	-62.9	0	0	0	0	112.9	T444 T445 R450 L451 S452	T444-S448 PolarHBondContact O-N 3.14Å; T444-S448 PolarHBondContact O-OG 2.93Å; T445-S448 PolarHBondContact O-N 2.89Å; S448-R450 VanDerWaalsContact C-N 3.34Å; S448-R450 PolarHBondContact O-N 3.29Å; S448-L451 PolarHBondContact O-N 3.11Å; S448-S452 PolarHBondContact O-N 2.95Å; S448-S452 PolarHBondContact O-OG 3.39Å
449	E	77.8	Confident	74.2	Confident	107 Å²	107	112.3 Å²	112.3	50%	0.5	56%	0.558	S	S	.	*	H	α-helix	trans	-65.8	-33.1	174.6	-78	177.3	-179.9	0	0	113.1	T445 E447 S452 K453	T445-E449 WeakPolarHBondContact O-CG 3.45Å; T445-E449 PolarHBondContact O-N 2.91Å; E447-E449 PolarHBondContact O-N 3.38Å; E449-S452 PolarHBondContact O-OG 3.45Å; E449-S452 VanDerWaalsContact O-OG 3.05Å; E449-K453 WeakPolarHBondContact O-CB 3.42Å; E449-K453 WeakPolarHBondContact O-CG 3.44Å; E449-K453 PolarHBondContact O-N 3.47Å; E449-K453 VanDerWaalsContact O-N 3.14Å
450	R	74.6	Confident	72.8	Confident	199 Å²	199	110.3 Å²	110.3	75%	0.751	55%	0.554	S	S	*	*	H	α-helix	trans	-70.7	-42.3	174	-78.6	178.2	-178.9	-161.6	-1.7	111.4	R446 E447 S448 K453 S454	R446-R450 WeakPolarHBondContact O-CG 3.34Å; R446-R450 PolarHBondContact O-N 2.87Å; R446-R450 VanDerWaalsContact O-N 3.1Å; E447-R450 PolarHBondContact O-N 3.5Å; S448-R450 VanDerWaalsContact C-N 3.34Å; S448-R450 PolarHBondContact O-N 3.29Å; R450-K453 PolarHBondContact O-N 2.94Å; R450-S454 WeakPolarHBondContact O-CB 3.46Å; R450-S454 PolarHBondContact O-N 2.65Å
451	L	73.1	Confident	71.1	Confident	104 Å²	104	113.2 Å²	113.2	55%	0.545	56%	0.564	S	S	.	*	H	α-helix	trans	-64.6	-40.3	176.7	-75.9	160	0	0	0	111.9	E447 S448 S454 K455	E447-L451 HydrophobicContact CG-CD1 4.39Å; E447-L451 WeakPolarHBondContact O-CG 3.39Å; E447-L451 PolarHBondContact O-N 3.1Å; S448-L451 PolarHBondContact O-N 3.11Å; L451-S454 PolarHBondContact O-N 3.43Å; L451-K455 PolarHBondContact O-N 3.42Å
452	S	71.8	Confident	69.5	Low	68 Å²	68	115 Å²	115	48%	0.476	57%	0.57	S	S	.	*	H	α-helix	trans	-67.3	-40.9	176.5	67.9	0	0	0	0	112.3	S448 E449 K455 H456	S448-S452 PolarHBondContact O-N 2.95Å; S448-S452 PolarHBondContact O-OG 3.39Å; E449-S452 PolarHBondContact O-OG 3.45Å; E449-S452 VanDerWaalsContact O-OG 3.05Å; S452-K455 PolarHBondContact O-N 2.95Å; S452-H456 WeakPolarHBondContact O-CB 3.39Å; S452-H456 PolarHBondContact O-N 3.28Å
453	K	72	Confident	67.9	Low	148 Å²	148	115.3 Å²	115.3	64%	0.643	58%	0.576	S	S	*	*	H	α-helix	trans	-64.5	-38.2	172.7	-76.8	-179.8	178	-179.4	0	112.5	E449 R450 H456 S457	E449-K453 WeakPolarHBondContact O-CB 3.42Å; E449-K453 WeakPolarHBondContact O-CG 3.44Å; E449-K453 PolarHBondContact O-N 3.47Å; E449-K453 VanDerWaalsContact O-N 3.14Å; R450-K453 PolarHBondContact O-N 2.94Å; K453-H456 PolarHBondContact O-N 2.98Å; K453-S457 WeakPolarHBondContact O-CB 3.47Å; K453-S457 PolarHBondContact O-N 3.04Å; K453-S457 PolarHBondContact O-OG 2.95Å
454	S	66.9	Low	66.4	Low	60 Å²	60	113.7 Å²	113.7	42%	0.42	58%	0.578	S	S	.	*	H	α-helix	trans	-62.7	-48.2	175.2	-166.4	0	0	0	0	111.5	R450 L451 H456 S457 E458	R450-S454 WeakPolarHBondContact O-CB 3.46Å; R450-S454 PolarHBondContact O-N 2.65Å; L451-S454 PolarHBondContact O-N 3.43Å; S454-H456 VanDerWaalsContact C-N 3.33Å; S454-H456 PolarHBondContact O-N 3.37Å; S454-S457 WeakPolarHBondContact O-CB 3.43Å; S454-S457 PolarHBondContact O-N 3.23Å; S454-S457 VanDerWaalsContact O-N 3.11Å; S454-E458 PolarHBondContact O-N 3.4Å
455	K	63.6	Low	64.8	Low	139 Å²	139	113.6 Å²	113.6	60%	0.604	58%	0.581	S	S	*	*	H	α-helix	trans	-60.9	-41.5	175.8	-77.2	-175.3	173.4	-173.1	0	112.4	L451 S452 S457 E458 D459	L451-K455 PolarHBondContact O-N 3.42Å; S452-K455 PolarHBondContact O-N 2.95Å; K455-S457 VanDerWaalsContact C-N 3.27Å; K455-S457 PolarHBondContact O-N 3.33Å; K455-E458 PolarHBondContact O-N 3.18Å; K455-D459 WeakPolarHBondContact O-CB 3.41Å; K455-D459 PolarHBondContact O-N 3.42Å
456	H	58.2	Low	62.9	Low	132 Å²	132	116 Å²	116	61%	0.611	59%	0.591	S	S	*	*	H	α-helix	trans	-65	-32.8	176	-159	55.3	0	0	0	112.3	S452 K453 S454 V460	S452-H456 WeakPolarHBondContact O-CB 3.39Å; S452-H456 PolarHBondContact O-N 3.28Å; K453-H456 PolarHBondContact O-N 2.98Å; S454-H456 VanDerWaalsContact C-N 3.33Å; S454-H456 PolarHBondContact O-N 3.37Å; H456-V460 WeakPolarHBondContact O-CB 3.35Å; H456-V460 WeakPolarHBondContact O-CG2 3.44Å; H456-V460 PolarHBondContact O-N 3.47Å; H456-V460 VanDerWaalsContact O-N 3.12Å
457	S	57.1	Low	61.2	Low	79 Å²	79	113 Å²	113	55%	0.552	59%	0.594	S	S	*	*	H	α-helix	trans	-70.9	-40.3	175.2	-49.5	0	0	0	0	111.8	K453 S454 K455 N461	K453-S457 WeakPolarHBondContact O-CB 3.47Å; K453-S457 PolarHBondContact O-N 3.04Å; K453-S457 PolarHBondContact O-OG 2.95Å; S454-S457 WeakPolarHBondContact O-CB 3.43Å; S454-S457 PolarHBondContact O-N 3.23Å; S454-S457 VanDerWaalsContact O-N 3.11Å; K455-S457 VanDerWaalsContact C-N 3.27Å; K455-S457 PolarHBondContact O-N 3.33Å; S457-N461 PolarHBondContact O-N 2.93Å; S457-N461 VanDerWaalsContact O-N 3.12Å
458	E	57	Low	59.6	Low	122 Å²	122	112.9 Å²	112.9	57%	0.57	61%	0.605	S	S	*	*	H	α-helix	trans	-66.1	-45.2	174.4	-76.1	176.8	159.5	0	0	111.8	S454 K455 V460 N461 V462	S454-E458 PolarHBondContact O-N 3.4Å; K455-E458 PolarHBondContact O-N 3.18Å; E458-V460 VanDerWaalsContact C-N 3.31Å; E458-V460 PolarHBondContact O-N 3.48Å; E458-N461 PolarHBondContact O-N 3.48Å; E458-N461 VanDerWaalsContact O-N 3.12Å; E458-V462 WeakPolarHBondContact O-CG2 3.15Å; E458-V462 PolarHBondContact O-N 3.12Å
459	D	55.3	Low	58.1	Low	107 Å²	107	115.1 Å²	115.1	57%	0.572	62%	0.62	S	S	*	*	H	α-helix	trans	-62.7	-35.9	177.7	-78.9	-26	0	0	0	112.6	K455 K463	K455-D459 WeakPolarHBondContact O-CB 3.41Å; K455-D459 PolarHBondContact O-N 3.42Å; D459-K463 PolarHBondContact O-N 3.41Å
460	V	55.8	Low	56.3	Low	78 Å²	78	116.7 Å²	116.7	47%	0.473	64%	0.637	S	S	.	*	H	α-helix	trans	-68.6	-38.8	174.1	170.2	0	0	0	0	111	H456 E458 K463 V464	H456-V460 WeakPolarHBondContact O-CB 3.35Å; H456-V460 WeakPolarHBondContact O-CG2 3.44Å; H456-V460 PolarHBondContact O-N 3.47Å; H456-V460 VanDerWaalsContact O-N 3.12Å; E458-V460 VanDerWaalsContact C-N 3.31Å; E458-V460 PolarHBondContact O-N 3.48Å; V460-K463 PolarHBondContact O-N 3Å; V460-V464 VanDerWaalsContact O-CG2 3.23Å; V460-V464 WeakPolarHBondContact O-CG2 3.23Å; V460-V464 PolarHBondContact O-N 3.33Å
461	N	50.5	Low	54.7	Low	122 Å²	122	113.6 Å²	113.6	65%	0.652	64%	0.64	S	S	*	*	H	α-helix	trans	-70	-36.9	178.9	-129.2	9.8	0	0	0	112.3	S457 E458 V464 S465	S457-N461 PolarHBondContact O-N 2.93Å; S457-N461 VanDerWaalsContact O-N 3.12Å; E458-N461 PolarHBondContact O-N 3.48Å; E458-N461 VanDerWaalsContact O-N 3.12Å; N461-V464 PolarHBondContact O-N 3.37Å; N461-S465 PolarHBondContact O-N 3.12Å; N461-S465 PolarHBondContact O-OG 3.33Å
462	V	53.6	Low	53	Low	91 Å²	91	113.8 Å²	113.8	55%	0.552	65%	0.65	S	S	*	*	H	α-helix	trans	-67.4	-35.1	175.2	173.7	0	0	0	0	111.7	E458 V464 S465	E458-V462 WeakPolarHBondContact O-CG2 3.15Å; E458-V462 PolarHBondContact O-N 3.12Å; V462-V464 VanDerWaalsContact C-N 3.33Å; V462-V464 PolarHBondContact O-N 3.38Å; V462-S465 PolarHBondContact O-N 3.12Å; V462-S465 PolarHBondContact O-OG 2.82Å
463	K	50.7	Low	51.5	Low	183 Å²	183	119.6 Å²	119.6	80%	0.796	67%	0.67	S	S	*	*	H	α-helix	trans	-70	-25.5	176.3	-104.8	178.6	176.1	178.3	0	114.1	D459 V460	D459-K463 PolarHBondContact O-N 3.41Å; V460-K463 PolarHBondContact O-N 3Å
464	V	53.3	Low	49.7	Very low	116 Å²	116	124.4 Å²	124.4	70%	0.703	68%	0.684	S	S	*	*	H	α-helix	trans	-82.7	-20.4	179.6	177.3	0	0	0	0	111.6	V460 N461 V462	V460-V464 VanDerWaalsContact O-CG2 3.23Å; V460-V464 WeakPolarHBondContact O-CG2 3.23Å; V460-V464 PolarHBondContact O-N 3.33Å; N461-V464 PolarHBondContact O-N 3.37Å; V462-V464 VanDerWaalsContact C-N 3.33Å; V462-V464 PolarHBondContact O-N 3.38Å
465	S	48.1	Very low	48.4	Very low	82 Å²	82	129.9 Å²	129.9	57%	0.573	70%	0.703	S	S	*	*	S	Bend	trans	-88.2	-1.9	-177.5	50.3	0	0	0	0	116.5	N461 V462	N461-S465 PolarHBondContact O-N 3.12Å; N461-S465 PolarHBondContact O-OG 3.33Å; V462-S465 PolarHBondContact O-N 3.12Å; V462-S465 PolarHBondContact O-OG 2.82Å
466	N	45.4	Very low	47.1	Very low	130 Å²	130	130 Å²	130	70%	0.695	72%	0.716	S	S	*	*	P	Polyproline II helix	trans	-95.3	117	175.9	-82.1	-5.1	0	0	0	111
467	P	45.4	Very low	46.1	Very low	111 Å²	111	131 Å²	131	72%	0.721	73%	0.725	S	S	*	*	P	Polyproline II helix	trans	-77.6	160.3	176.2	32.6	-32.4	0	0	0	111.4
468	P	45.2	Very low	45.1	Very low	124 Å²	124	138.7 Å²	138.7	81%	0.805	76%	0.758	S	S	*	*	P	Polyproline II helix	trans	-70.8	139.3	-179.8	-4.3	20.1	0	0	0	111.2
469	S	44	Very low	44.5	Very low	116 Å²	116	139.6 Å²	139.6	81%	0.811	77%	0.767	S	S	*	*	P	Polyproline II helix	trans	-61.6	128.3	173.8	51.3	0	0	0	0	112.2	T471	S469-T471 PolarHBondContact O-N 3.46Å
470	V	41.6	Very low	43.9	Very low	140 Å²	140	141.3 Å²	141.3	85%	0.848	78%	0.778	S	S	*	*	P	Polyproline II helix	trans	-63.9	120.2	172.9	177.7	0	0	0	0	110.5
471	T	39.7	Very low	43.3	Very low	133 Å²	133	144.8 Å²	144.8	82%	0.816	80%	0.795	S	S	*	*	P	Polyproline II helix	trans	-73.9	122.6	163.7	29.7	0	0	0	0	109.8	S469	S469-T471 PolarHBondContact O-N 3.46Å
472	S	37.6	Very low	42.8	Very low	109 Å²	109	146.1 Å²	146.1	76%	0.762	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-80.5	124.2	177.2	71.7	0	0	0	0	111.6
473	E	39.6	Very low	42.2	Very low	190 Å²	190	149.6 Å²	149.6	89%	0.888	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-64.2	140	157.2	-73.9	172.1	148.8	0	0	109.8
474	R	35.9	Very low	41.6	Very low	248 Å²	248	147.3 Å²	147.3	94%	0.936	82%	0.82	S	S	*	*			trans	-134.2	101.1	163.7	-141.3	-178.9	-168.1	-175	2.8	107.9
475	E	38.3	Very low	40.8	Very low	175 Å²	175	149.6 Å²	149.6	82%	0.818	83%	0.829	S	S	*	*			trans	-64.2	142.3	163.6	-69.6	177.5	138.1	0	0	110.3
476	T	37.4	Very low	40.2	Very low	143 Å²	143	154.8 Å²	154.8	88%	0.877	85%	0.848	S	S	*	*			trans	-152.4	127	138.9	31.8	0	0	0	0	110.1
477	N	37	Very low	39.8	Very low	151 Å²	151	156.8 Å²	156.8	81%	0.807	86%	0.861	S	S	*	*			trans	-58.9	144.2	173.9	-64.3	-54.1	0	0	0	114
478	I	35.4	Very low	39.2	Very low	242 Å²	242	161 Å²	161	100%	1.241	87%	0.874	S	S	*	*				-169.8	0	106.2	-84.4	164.3	0	0	0	107.7

Retrieved 478 of 478 residues in 387.4 ms (Link to these results)

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