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Delta(14)-sterol reductase TM7SF2

Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis.

AlphaFold DB , UniProt , Accession A0A096MLS2, Species PAPAN (Papio anubis, Olive baboon), Gene TM7SF2, Length 418 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M34.3Very low51Low241 Ų241116.8 Ų116.8100%1.18769%0.689SS**  0113.40-78.7173.6-14200107
2A30.5Very low54Low94 Ų94109.4 Ų109.478%0.77764%0.643SS**PPolyproline II helixtrans-62.3135.316900000107.9
3P33.4Very low56.7Low107 Ų107104.3 Ų104.370%0.69561%0.608SS**PPolyproline II helixtrans-59.7144.4174.325.6-31.3000108.8E5P3-E5 PolarHBondContact O-N 2.76Å; P3-E5 VanDerWaalsContact O-N 3.12Å
4P35.9Very low59Low129 Ų129101.9 Ų101.984%0.83862%0.616SS**PPolyproline II helixtrans-58.9120.6177.624.4-31.4000108.5G6P4-G6 PolarHBondContact O-N 2.8Å
5E42.8Very low61.2Low140 Ų14095.5 Ų95.565%0.65458%0.58SS**  trans-65109.8173.7-65.4-167.9166.400107.9P3 R8P3-E5 PolarHBondContact O-N 2.76Å; P3-E5 VanDerWaalsContact O-N 3.12Å; E5-R8 IonicContact OE1-CZ 2.71Å; E5-R8 IonicContact OE1-NE 3.06Å; E5-R8 IonicContact OE1-NH2 3.52Å; E5-R8 PolarHBondContact OE1-NH2 3.42Å; E5-R8 IonicContact OE2-CZ 3.11Å; E5-R8 IonicContact OE2-NE 3.64Å; E5-R8 PolarHBondContact OE2-NE 2.81Å; E5-R8 IonicContact OE2-NH2 2.64Å; E5-R8 PolarHBondContact OE2-NH2 3.25Å
6G46.5Very low63.3Low50 Ų5092 Ų9252%0.51556%0.559SS.*  trans-55.9161165.600000110.3P4 R8P4-G6 PolarHBondContact O-N 2.8Å; G6-R8 PolarHBondContact O-N 3.07Å
7P47.7Very low65.1Low140 Ų14095.5 Ų95.591%0.90957%0.573SS**  trans-54.6111.8-179.721.1-30.6000109.9A9P7-A9 PolarHBondContact O-N 3.3Å
8R59.6Low66.8Low164 Ų16491.2 Ų91.262%0.61955%0.552SS**PPolyproline II helixtrans-60.8130.5178.5-66.9-178.8-176.9-168.3-4.7108.4E5 G6E5-R8 IonicContact OE1-CZ 2.71Å; E5-R8 IonicContact OE1-NE 3.06Å; E5-R8 IonicContact OE1-NH2 3.52Å; E5-R8 PolarHBondContact OE1-NH2 3.42Å; E5-R8 IonicContact OE2-CZ 3.11Å; E5-R8 IonicContact OE2-NE 3.64Å; E5-R8 PolarHBondContact OE2-NE 2.81Å; E5-R8 IonicContact OE2-NH2 2.64Å; E5-R8 PolarHBondContact OE2-NH2 3.25Å; G6-R8 PolarHBondContact O-N 3.07Å
9A67.1Low68.3Low45 Ų4586.4 Ų86.437%0.37252%0.523SS..PPolyproline II helixtrans-55.8142.5176.900000110.1P7 L11P7-A9 PolarHBondContact O-N 3.3Å; A9-L11 PolarHBondContact O-N 3.02Å
10P77.9Confident69.6Low80 Ų8083.8 Ų83.852%0.51951%0.511SS..PPolyproline II helixtrans-60.1133.8178.225.6-33.1000109.7
11L85.8Confident70.9Confident95 Ų9581.9 Ų81.950%0.49750%0.504SS..PPolyproline II helixtrans-67135.3177.8-62.4172.2000110.1A9 Y171A9-L11 PolarHBondContact O-N 3.02Å; L11-Y171 HydrophobicContact CD2-CD1 4.2Å; L11-Y171 HydrophobicContact CD2-CE1 3.67Å; L11-Y171 HydrophobicContact CD2-CE2 4.31Å
12E86.6Confident73.9Confident28 Ų2872.6 Ų72.613%0.13146%0.459CS..  trans-106.5175.7179-61.4-174.6149.300109.8G14 G15 Y171 R389E12-G14 PolarHBondContact O-N 3.1Å; E12-G15 PolarHBondContact O-N 3.13Å; E12-Y171 PolarHBondContact N-OH 2.96Å; E12-Y171 WeakPolarHBondContact O-CE2 3.36Å; E12-R389 IonicContact OE1-CZ 3.87Å; E12-R389 IonicContact OE1-NE 3.85Å; E12-R389 PolarHBondContact OE1-NE 3.37Å; E12-R389 IonicContact OE1-NH2 3.75Å; E12-R389 PolarHBondContact OE1-NH2 2.96Å; E12-R389 IonicContact OE2-CZ 3.79Å; E12-R389 IonicContact OE2-NE 3.28Å; E12-R389 PolarHBondContact OE2-NE 3.09Å; E12-R389 IonicContact OE2-NH2 2.85Å; E12-R389 PolarHBondContact OE2-NH2 3.36Å
13F88.8Confident77Confident43 Ų4369.2 Ų69.219%0.18943%0.427CS..THydrogen-bonded Turntrans54.132.1174.5-54.2-81.6000114.7G15 G18 A19 L22 F174 L175 M258 H385F13-G15 VanDerWaalsContact C-N 3.26Å; F13-G15 PolarHBondContact O-N 2.91Å; F13-G18 CarbonylContact O-C 3.45Å; F13-G18 WeakPolarHBondContact O-CA 3.38Å; F13-A19 PolarHBondContact O-N 2.84Å; F13-L22 HydrophobicContact CB-CD1 4.01Å; F13-L22 HydrophobicContact CD1-CD1 4.11Å; F13-L22 HydrophobicContact CG-CD1 4.46Å; F13-F174 HydrophobicContact CB-CE1 4.27Å; F13-F174 HydrophobicContact CD1-CE1 4.39Å; F13-F174 HydrophobicContact CD2-CE1 4.26Å; F13-F174 HydrophobicContact CG-CE1 4.04Å; F13-L175 HydrophobicContact CD2-CD2 3.81Å; F13-L175 HydrophobicContact CE2-CD2 3.64Å; F13-M258 HydrophobicContact CD1-SD 4.37Å; F13-M258 HydrophobicContact CD2-SD 4.4Å; F13-M258 HydrophobicContact CE1-SD 3.69Å; F13-M258 HydrophobicContact CE2-CE 4.29Å; F13-M258 HydrophobicContact CE2-SD 3.75Å; F13-M258 HydrophobicContact CZ-CE 4.05Å; F13-M258 HydrophobicContact CZ-SD 3.33Å; F13-M258 WeakPolarHBondContact CZ-SD 3.27Å; F13-H385 AromaticContact CE1-CE1 3.59Å; F13-H385 AromaticContact CZ-CE1 3.78Å
14G89.4Confident80Confident70 Ų7070.1 Ų70.172%0.72243%0.426SS*.THydrogen-bonded Turntrans71.318.2-177.500000114.4E12 G18E12-G14 PolarHBondContact O-N 3.1Å; G14-G18 PolarHBondContact O-N 3.13Å
15G92.6Very high82.8Confident7 Ų768.7 Ų68.77%0.07241%0.41CS..Hα-helixtrans66.6-157.5-178.900000113E12 F13 L17 G18 A19 Y171E12-G15 PolarHBondContact O-N 3.13Å; F13-G15 VanDerWaalsContact C-N 3.26Å; F13-G15 PolarHBondContact O-N 2.91Å; G15-L17 VanDerWaalsContact C-N 3.32Å; G15-L17 PolarHBondContact O-N 2.78Å; G15-G18 PolarHBondContact O-N 3.16Å; G15-A19 WeakPolarHBondContact O-CB 3.41Å; G15-A19 PolarHBondContact O-N 3.06Å; G15-Y171 VanDerWaalsContact C-CD2 3.49Å
16P93.9Very high85.4Confident39 Ų3963.6 Ų63.625%0.25339%0.388SS..Hα-helixtrans-56.9-39.1-175.2-29.835.8000114.9A20 N168P16-A20 VanDerWaalsContact O-CB 3.28Å; P16-A20 WeakPolarHBondContact O-CB 3.45Å; P16-A20 PolarHBondContact O-N 2.98Å; P16-N168 HydrophobicContact CB-CB 4.42Å; P16-N168 HydrophobicContact CG-CB 3.94Å
17L94.8Very high87.8Confident151 Ų15161.9 Ų61.979%0.79137%0.367SS*.Hα-helixtrans-68.8-43179.5-68.4176.7000111.7G15 A20 A21G15-L17 VanDerWaalsContact C-N 3.32Å; G15-L17 PolarHBondContact O-N 2.78Å; L17-A20 PolarHBondContact O-N 2.85Å; L17-A21 WeakPolarHBondContact O-CB 3.37Å; L17-A21 PolarHBondContact O-N 3.1Å
18G94.8Very high90Very high19 Ų1957.9 Ų57.920%0.19635%0.346CS..Hα-helixtrans-67.3-41.8176.800000112.1F13 G14 G15 A20 A21 L22F13-G18 CarbonylContact O-C 3.45Å; F13-G18 WeakPolarHBondContact O-CA 3.38Å; G14-G18 PolarHBondContact O-N 3.13Å; G15-G18 PolarHBondContact O-N 3.16Å; G18-A20 PolarHBondContact O-N 3.5Å; G18-A21 PolarHBondContact O-N 3.18Å; G18-L22 WeakPolarHBondContact O-CB 3.31Å; G18-L22 VanDerWaalsContact O-CG 3.27Å; G18-L22 WeakPolarHBondContact O-CG 3.29Å; G18-L22 PolarHBondContact O-N 3.36Å
19A94.9Very high91.8Very high0 Ų052.2 Ų52.20%033%0.33CS..Hα-helixtrans-58.3-46.1171.900000112.1F13 G15 A21 L22 L23 Y171 F174F13-A19 PolarHBondContact O-N 2.84Å; G15-A19 WeakPolarHBondContact O-CB 3.41Å; G15-A19 PolarHBondContact O-N 3.06Å; A19-A21 VanDerWaalsContact C-N 3.34Å; A19-A21 PolarHBondContact O-N 3.48Å; A19-L22 PolarHBondContact O-N 3.35Å; A19-L23 WeakPolarHBondContact O-CG 3.25Å; A19-L23 PolarHBondContact O-N 3.27Å; A19-Y171 HydrophobicContact CB-CD2 3.78Å; A19-Y171 HydrophobicContact CB-CE2 4.49Å; A19-F174 HydrophobicContact CB-CB 3.88Å; A19-F174 HydrophobicContact CB-CD1 3.79Å; A19-F174 HydrophobicContact CB-CG 3.82Å
20A95.7Very high93.2Very high34 Ų3450.1 Ų50.128%0.28131%0.312SS..Hα-helixtrans-60.7-41.8176.500000112.4P16 L17 G18 I170P16-A20 VanDerWaalsContact O-CB 3.28Å; P16-A20 WeakPolarHBondContact O-CB 3.45Å; P16-A20 PolarHBondContact O-N 2.98Å; L17-A20 PolarHBondContact O-N 2.85Å; G18-A20 PolarHBondContact O-N 3.5Å; A20-I170 HydrophobicContact CB-CG2 3.87Å
21A96.8Very high94Very high44 Ų4448 Ų4836%0.36430%0.295SS..Hα-helixtrans-64.4-43.5175.500000111.4L17 G18 A19 L23 L24 L25L17-A21 WeakPolarHBondContact O-CB 3.37Å; L17-A21 PolarHBondContact O-N 3.1Å; G18-A21 PolarHBondContact O-N 3.18Å; A19-A21 VanDerWaalsContact C-N 3.34Å; A19-A21 PolarHBondContact O-N 3.48Å; A21-L23 VanDerWaalsContact C-N 3.32Å; A21-L23 PolarHBondContact O-N 3.26Å; A21-L24 PolarHBondContact O-N 3.41Å; A21-L24 VanDerWaalsContact O-N 3.1Å; A21-L25 HydrophobicContact CB-CD1 4.15Å; A21-L25 WeakPolarHBondContact O-CB 3.32Å; A21-L25 VanDerWaalsContact O-CG 3.3Å; A21-L25 WeakPolarHBondContact O-CG 3.48Å; A21-L25 PolarHBondContact O-N 3.21Å
22L96.1Very high94.5Very high46 Ų4645.2 Ų45.224%0.24128%0.279CS..Hα-helixtrans-65.8-30.6-179.6-71.7171.2000113.2F13 G18 A19 L24 L26 F174F13-L22 HydrophobicContact CB-CD1 4.01Å; F13-L22 HydrophobicContact CD1-CD1 4.11Å; F13-L22 HydrophobicContact CG-CD1 4.46Å; G18-L22 WeakPolarHBondContact O-CB 3.31Å; G18-L22 VanDerWaalsContact O-CG 3.27Å; G18-L22 WeakPolarHBondContact O-CG 3.29Å; G18-L22 PolarHBondContact O-N 3.36Å; A19-L22 PolarHBondContact O-N 3.35Å; L22-L24 PolarHBondContact O-N 3.5Å; L22-L26 HydrophobicContact CB-CD1 4.24Å; L22-L26 HydrophobicContact CB-CG 4.42Å; L22-L26 HydrophobicContact CD2-CD2 4.5Å; L22-L26 HydrophobicContact CD2-CG 4.26Å; L22-L26 VanDerWaalsContact O-CB 3.32Å; L22-L26 WeakPolarHBondContact O-CB 3.37Å; L22-L26 WeakPolarHBondContact O-CG 3.27Å; L22-L26 PolarHBondContact O-N 3.4Å; L22-L26 VanDerWaalsContact O-N 3.07Å; L22-F174 HydrophobicContact CB-CE2 3.7Å; L22-F174 HydrophobicContact CB-CZ 3.82Å; L22-F174 HydrophobicContact CD1-CE1 4.29Å; L22-F174 HydrophobicContact CD1-CZ 3.8Å; L22-F174 HydrophobicContact CG-CZ 4.47Å
23L96.5Very high94.9Very high22 Ų2244 Ų4412%0.11527%0.274CS..Hα-helixtrans-55.5-30.4171.6-73.4174.5000112.8A19 A21 P27 F142 I170 F173 F174 F257A19-L23 WeakPolarHBondContact O-CG 3.25Å; A19-L23 PolarHBondContact O-N 3.27Å; A21-L23 VanDerWaalsContact C-N 3.32Å; A21-L23 PolarHBondContact O-N 3.26Å; L23-P27 VanDerWaalsContact O-CD 3.3Å; L23-P27 WeakPolarHBondContact O-CD 3.38Å; L23-P27 WeakPolarHBondContact O-CG 3.06Å; L23-F142 HydrophobicContact CD2-CE1 4.44Å; L23-I170 HydrophobicContact CD1-CG2 3.87Å; L23-F173 HydrophobicContact CD1-CD1 4.27Å; L23-F173 HydrophobicContact CD2-CD1 4Å; L23-F173 HydrophobicContact CD2-CE1 3.79Å; L23-F174 HydrophobicContact CD2-CD2 3.8Å; L23-F174 HydrophobicContact CG-CD2 4.05Å; L23-F257 HydrophobicContact CD2-CB 3.92Å; L23-F257 HydrophobicContact CD2-CD1 3.28Å; L23-F257 HydrophobicContact CD2-CD2 4.24Å; L23-F257 HydrophobicContact CD2-CE1 3.75Å; L23-F257 HydrophobicContact CD2-CG 3.54Å; L23-F257 HydrophobicContact CD2-CZ 4.41Å
24L95.6Very high95.2Very high127 Ų12742 Ų4267%0.66527%0.265SS*.Hα-helixtrans-99.2-43.9-180-57.8178.6000111.9A21 L22 L26 P27 A28A21-L24 PolarHBondContact O-N 3.41Å; A21-L24 VanDerWaalsContact O-N 3.1Å; L22-L24 PolarHBondContact O-N 3.5Å; L24-L26 PolarHBondContact O-N 3.03Å; L24-P27 WeakPolarHBondContact O-CD 3.31Å; L24-A28 VanDerWaalsContact O-CB 3.24Å; L24-A28 WeakPolarHBondContact O-CB 3.22Å; L24-A28 PolarHBondContact O-N 2.87Å
25L95.6Very high95.4Very high98 Ų9840.2 Ų40.251%0.51324%0.239SC..Hα-helixtrans-67-36.2-174.8-70.5175.1000112.6A21 T29A21-L25 HydrophobicContact CB-CD1 4.15Å; A21-L25 WeakPolarHBondContact O-CB 3.32Å; A21-L25 VanDerWaalsContact O-CG 3.3Å; A21-L25 WeakPolarHBondContact O-CG 3.48Å; A21-L25 PolarHBondContact O-N 3.21Å; L25-T29 VanDerWaalsContact O-CB 3.25Å; L25-T29 WeakPolarHBondContact O-CB 3.31Å; L25-T29 PolarHBondContact O-N 2.89Å; L25-T29 PolarHBondContact O-OG1 2.92Å
26L96.4Very high95.4Very high34 Ų3440 Ų4018%0.17824%0.237CC..Hα-helixtrans-66-54.2-179.9-69.3172.8000111.6L22 L24 A28 T29 M30 F174 F261 W266L22-L26 HydrophobicContact CB-CD1 4.24Å; L22-L26 HydrophobicContact CB-CG 4.42Å; L22-L26 HydrophobicContact CD2-CD2 4.5Å; L22-L26 HydrophobicContact CD2-CG 4.26Å; L22-L26 VanDerWaalsContact O-CB 3.32Å; L22-L26 WeakPolarHBondContact O-CB 3.37Å; L22-L26 WeakPolarHBondContact O-CG 3.27Å; L22-L26 PolarHBondContact O-N 3.4Å; L22-L26 VanDerWaalsContact O-N 3.07Å; L24-L26 PolarHBondContact O-N 3.03Å; L26-A28 PolarHBondContact O-N 2.84Å; L26-T29 PolarHBondContact O-N 3.12Å; L26-M30 PolarHBondContact O-N 3.4Å; L26-F174 HydrophobicContact CD1-CE2 4.28Å; L26-F261 HydrophobicContact CB-CD1 4.14Å; L26-F261 HydrophobicContact CB-CE1 3.75Å; L26-W266 HydrophobicContact CD2-CH2 4.47Å; L26-W266 HydrophobicContact CD2-CZ3 4.25Å; L26-W266 WeakPolarHBondContact O-CZ3 3.42Å
27P97.1Very high95.3Very high13 Ų1338.2 Ų38.28%0.08423%0.225CC..Hα-helixtrans-56-47.3171.6-26.634.6000113.2L23 L24 T29 M30 F31 T138 F142 F257 F261L23-P27 VanDerWaalsContact O-CD 3.3Å; L23-P27 WeakPolarHBondContact O-CD 3.38Å; L23-P27 WeakPolarHBondContact O-CG 3.06Å; L24-P27 WeakPolarHBondContact O-CD 3.31Å; P27-T29 VanDerWaalsContact C-N 3.3Å; P27-T29 PolarHBondContact O-N 3.04Å; P27-M30 PolarHBondContact O-N 2.72Å; P27-F31 HydrophobicContact CB-CE2 4.37Å; P27-F31 WeakPolarHBondContact O-CD2 3.33Å; P27-F31 PolarHBondContact O-N 3.37Å; P27-T138 HydrophobicContact CB-CG2 4.07Å; P27-T138 HydrophobicContact CG-CG2 4.18Å; P27-F142 HydrophobicContact CG-CE2 4.32Å; P27-F142 HydrophobicContact CG-CZ 4.49Å; P27-F257 HydrophobicContact CG-CZ 4.09Å; P27-F261 HydrophobicContact CB-CE2 4.26Å; P27-F261 HydrophobicContact CB-CZ 4.22Å; P27-F261 HydrophobicContact CG-CD2 4.45Å; P27-F261 HydrophobicContact CG-CE2 3.89Å; P27-F261 HydrophobicContact CG-CZ 3.97Å
28A95.2Very high95Very high57 Ų5735.6 Ų35.647%0.47121%0.205SC..Hα-helixtrans-59.4-41.7-178.500000112.2L24 L26 F31 H32L24-A28 VanDerWaalsContact O-CB 3.24Å; L24-A28 WeakPolarHBondContact O-CB 3.22Å; L24-A28 PolarHBondContact O-N 2.87Å; L26-A28 PolarHBondContact O-N 2.84Å; A28-F31 PolarHBondContact O-N 2.93Å; A28-H32 VanDerWaalsContact O-CB 3.3Å; A28-H32 WeakPolarHBondContact O-CB 3.42Å; A28-H32 PolarHBondContact O-N 2.8Å
29T95.8Very high94.5Very high45 Ų4536 Ų3628%0.27620%0.204SC..Hα-helixtrans-64.9-45.2176.8-580000111L25 L26 P27 F31 H32 L33 W266 F374L25-T29 VanDerWaalsContact O-CB 3.25Å; L25-T29 WeakPolarHBondContact O-CB 3.31Å; L25-T29 PolarHBondContact O-N 2.89Å; L25-T29 PolarHBondContact O-OG1 2.92Å; L26-T29 PolarHBondContact O-N 3.12Å; P27-T29 VanDerWaalsContact C-N 3.3Å; P27-T29 PolarHBondContact O-N 3.04Å; T29-F31 PolarHBondContact O-N 3.46Å; T29-H32 WeakPolarHBondContact O-CB 3.15Å; T29-H32 PolarHBondContact O-N 3.33Å; T29-L33 HydrophobicContact CG2-CD1 4.11Å; T29-L33 HydrophobicContact CG2-CG 4.43Å; T29-L33 VanDerWaalsContact O-CG 3.25Å; T29-L33 WeakPolarHBondContact O-CG 3.47Å; T29-L33 PolarHBondContact O-N 3.19Å; T29-W266 HydrophobicContact CG2-CH2 3.87Å; T29-W266 HydrophobicContact CG2-CZ3 4.2Å; T29-F374 HydrophobicContact CG2-CE2 4.21Å; T29-F374 HydrophobicContact CG2-CZ 3.88Å
30M96.9Very high93.9Very high0 Ų039 Ų390%024%0.235CC..Hα-helixtrans-58.2-49.1176.7-178.6-175.269.500111.4L26 P27 H32 L33 L34 A134 T138 F261 A265 W266 F269 T270L26-M30 PolarHBondContact O-N 3.4Å; P27-M30 PolarHBondContact O-N 2.72Å; M30-H32 VanDerWaalsContact C-N 3.34Å; M30-H32 PolarHBondContact O-N 2.95Å; M30-L33 PolarHBondContact O-N 3.4Å; M30-L34 HydrophobicContact CG-CD1 4.46Å; M30-L34 WeakPolarHBondContact O-CG 3.41Å; M30-L34 PolarHBondContact O-N 3.29Å; M30-A134 HydrophobicContact CE-CB 3.94Å; M30-T138 VanDerWaalsContact CE-OG1 3.23Å; M30-T138 WeakPolarHBondContact CE-OG1 3.42Å; M30-F261 HydrophobicContact CB-CZ 4.42Å; M30-F261 HydrophobicContact CE-CE2 4.07Å; M30-F261 HydrophobicContact CE-CZ 3.97Å; M30-F261 HydrophobicContact SD-CE2 4.48Å; M30-F261 HydrophobicContact SD-CZ 4.01Å; M30-A265 HydrophobicContact CE-CB 4.34Å; M30-A265 HydrophobicContact SD-CB 4.04Å; M30-W266 HydrophobicContact CB-CE3 4.12Å; M30-W266 HydrophobicContact CB-CZ3 4.22Å; M30-F269 HydrophobicContact CG-CB 4.16Å; M30-F269 HydrophobicContact SD-CB 3.86Å; M30-F269 HydrophobicContact SD-CD2 4.12Å; M30-F269 HydrophobicContact SD-CG 4.37Å; M30-T270 HydrophobicContact CB-CG2 4.11Å; M30-T270 HydrophobicContact CG-CG2 3.78Å
31F95.4Very high93.4Very high35 Ų3540.6 Ų40.615%0.15424%0.243CC..Hα-helixtrans-63.2-40.2177.6-74-64.7000112.4P27 A28 T29 L33 L34 L35 L131 A134 F135 T138P27-F31 HydrophobicContact CB-CE2 4.37Å; P27-F31 WeakPolarHBondContact O-CD2 3.33Å; P27-F31 PolarHBondContact O-N 3.37Å; A28-F31 PolarHBondContact O-N 2.93Å; T29-F31 PolarHBondContact O-N 3.46Å; F31-L33 VanDerWaalsContact C-N 3.34Å; F31-L33 PolarHBondContact O-N 3.24Å; F31-L34 PolarHBondContact O-N 2.88Å; F31-L35 WeakPolarHBondContact O-CB 3.36Å; F31-L35 VanDerWaalsContact O-CG 3.25Å; F31-L35 WeakPolarHBondContact O-CG 3.37Å; F31-L35 PolarHBondContact O-N 3Å; F31-L131 HydrophobicContact CD1-CD1 3.66Å; F31-L131 HydrophobicContact CE1-CD1 4.11Å; F31-A134 HydrophobicContact CE1-CB 4Å; F31-A134 HydrophobicContact CZ-CB 4.47Å; F31-F135 HydrophobicContact CE1-CB 4.22Å; F31-F135 HydrophobicContact CZ-CB 4.15Å; F31-F135 HydrophobicContact CZ-CD2 4.22Å; F31-T138 HydrophobicContact CE2-CG2 4.49Å
32H94.9Very high93Very high37 Ų3738.6 Ų38.617%0.17123%0.226CC..Hα-helixtrans-57.4-46.5174.1174.966.3000111.7A28 T29 M30 L34 L35 A36 L44 G46A28-H32 VanDerWaalsContact O-CB 3.3Å; A28-H32 WeakPolarHBondContact O-CB 3.42Å; A28-H32 PolarHBondContact O-N 2.8Å; T29-H32 WeakPolarHBondContact O-CB 3.15Å; T29-H32 PolarHBondContact O-N 3.33Å; M30-H32 VanDerWaalsContact C-N 3.34Å; M30-H32 PolarHBondContact O-N 2.95Å; H32-L34 PolarHBondContact O-N 3.13Å; H32-L35 PolarHBondContact O-N 3.22Å; H32-A36 VanDerWaalsContact O-CB 3.23Å; H32-A36 WeakPolarHBondContact O-CB 3.38Å; H32-A36 PolarHBondContact O-N 3.25Å; H32-L44 PolarHBondContact NE2-O 3.41Å; H32-G46 PolarHBondContact CE1-O 3.49Å
33L95.7Very high92.6Very high2 Ų245 Ų451%0.0125%0.247CC..Hα-helixtrans-63-43.1178.6-65.8167.4000112.2T29 M30 F31 L35 A36 A37 L44 T270 L273 L371 F374T29-L33 HydrophobicContact CG2-CD1 4.11Å; T29-L33 HydrophobicContact CG2-CG 4.43Å; T29-L33 VanDerWaalsContact O-CG 3.25Å; T29-L33 WeakPolarHBondContact O-CG 3.47Å; T29-L33 PolarHBondContact O-N 3.19Å; M30-L33 PolarHBondContact O-N 3.4Å; F31-L33 VanDerWaalsContact C-N 3.34Å; F31-L33 PolarHBondContact O-N 3.24Å; L33-L35 PolarHBondContact O-N 3.46Å; L33-A36 PolarHBondContact O-N 3.1Å; L33-A37 WeakPolarHBondContact O-CB 3.33Å; L33-A37 PolarHBondContact O-N 3.16Å; L33-L44 HydrophobicContact CD2-CD1 3.65Å; L33-T270 HydrophobicContact CD1-CG2 4.02Å; L33-L273 HydrophobicContact CB-CD1 4.37Å; L33-L273 HydrophobicContact CD2-CD2 4.14Å; L33-L371 HydrophobicContact CD2-CD1 3.63Å; L33-F374 HydrophobicContact CD1-CD1 3.51Å; L33-F374 HydrophobicContact CD1-CE1 3.31Å; L33-F374 HydrophobicContact CD1-CE2 4.41Å; L33-F374 HydrophobicContact CD1-CG 4.18Å; L33-F374 HydrophobicContact CD1-CZ 3.8Å; L33-F374 HydrophobicContact CD2-CB 4.22Å; L33-F374 HydrophobicContact CD2-CD1 3.97Å; L33-F374 HydrophobicContact CD2-CD2 4.13Å; L33-F374 HydrophobicContact CD2-CE1 4.43Å; L33-F374 HydrophobicContact CD2-CG 3.81Å; L33-F374 HydrophobicContact CG-CD1 4.4Å; L33-F374 HydrophobicContact CG-CE1 4.47Å
34L94.7Very high92.3Very high3 Ų345.1 Ų45.12%0.01625%0.248CC..Hα-helixtrans-61.6-43.1176.4-68177.5000111.7M30 F31 H32 R38 L131 A134 F269M30-L34 HydrophobicContact CG-CD1 4.46Å; M30-L34 WeakPolarHBondContact O-CG 3.41Å; M30-L34 PolarHBondContact O-N 3.29Å; F31-L34 PolarHBondContact O-N 2.88Å; H32-L34 PolarHBondContact O-N 3.13Å; L34-R38 VanDerWaalsContact O-CG 3.3Å; L34-R38 WeakPolarHBondContact O-CG 3.29Å; L34-R38 PolarHBondContact O-N 3.26Å; L34-L131 HydrophobicContact CD1-CD1 4.48Å; L34-A134 HydrophobicContact CD1-CB 3.46Å; L34-A134 VanDerWaalsContact CD1-CB 3.46Å; L34-F269 HydrophobicContact CD1-CB 4.38Å; L34-F269 HydrophobicContact CD2-CB 4.27Å
35L93.7Very high91.9Very high31 Ų3145.6 Ų45.616%0.16225%0.25CS..Hα-helixtrans-68.9-41.4177.1-67.6171.8000111.5F31 H32 L33 R38 S39 P48 P52 L131F31-L35 WeakPolarHBondContact O-CB 3.36Å; F31-L35 VanDerWaalsContact O-CG 3.25Å; F31-L35 WeakPolarHBondContact O-CG 3.37Å; F31-L35 PolarHBondContact O-N 3Å; H32-L35 PolarHBondContact O-N 3.22Å; L33-L35 PolarHBondContact O-N 3.46Å; L35-R38 PolarHBondContact O-N 2.91Å; L35-S39 WeakPolarHBondContact O-CB 3.38Å; L35-S39 PolarHBondContact O-N 2.75Å; L35-P48 HydrophobicContact CB-CB 4.32Å; L35-P48 HydrophobicContact CD1-CB 4.17Å; L35-P48 HydrophobicContact CD1-CG 4.43Å; L35-P52 HydrophobicContact CD1-CG 4.19Å; L35-P52 HydrophobicContact CD2-CG 4.11Å; L35-L131 HydrophobicContact CD2-CD1 4.4Å; L35-L131 HydrophobicContact CD2-CD2 4.12Å
36A93.4Very high91.3Very high4 Ų443.3 Ų43.33%0.03325%0.25CS..Hα-helixtrans-61.7-44.6177.600000111.1H32 L33 R38 S39 A42 L371H32-A36 VanDerWaalsContact O-CB 3.23Å; H32-A36 WeakPolarHBondContact O-CB 3.38Å; H32-A36 PolarHBondContact O-N 3.25Å; L33-A36 PolarHBondContact O-N 3.1Å; A36-R38 VanDerWaalsContact C-N 3.27Å; A36-R38 PolarHBondContact O-N 3.08Å; A36-S39 WeakPolarHBondContact O-CB 3.32Å; A36-S39 PolarHBondContact O-N 3.4Å; A36-S39 VanDerWaalsContact O-N 3.08Å; A36-S39 PolarHBondContact O-OG 3.32Å; A36-A42 WeakPolarHBondContact O-CA 3.26Å; A36-L371 HydrophobicContact CB-CD1 4Å; A36-L371 HydrophobicContact CB-CD2 3.96Å
37A91.9Very high90.4Very high1 Ų147.5 Ų47.51%0.00828%0.279CS..Hα-helixtrans-63.4-33.4178.500000112.7L33 L273 Q276 L371L33-A37 WeakPolarHBondContact O-CB 3.33Å; L33-A37 PolarHBondContact O-N 3.16Å; A37-L273 HydrophobicContact CB-CD1 3.79Å; A37-Q276 HydrophobicContact CB-CB 4.13Å; A37-L371 HydrophobicContact CB-CD2 4.17Å
38R88.2Confident89.5Confident95 Ų9548.7 Ų48.736%0.35829%0.287SS..Hα-helixtrans-78-20.5175.1-67.7175.673.1122.510.3113.4L34 L35 A36 E128L34-R38 VanDerWaalsContact O-CG 3.3Å; L34-R38 WeakPolarHBondContact O-CG 3.29Å; L34-R38 PolarHBondContact O-N 3.26Å; L35-R38 PolarHBondContact O-N 2.91Å; A36-R38 VanDerWaalsContact C-N 3.27Å; A36-R38 PolarHBondContact O-N 3.08Å; R38-E128 IonicContact CZ-OE2 3.36Å; R38-E128 PolarHBondContact NH1-O 3.38Å; R38-E128 IonicContact NH2-OE2 3.28Å; R38-E128 PolarHBondContact NH2-OE2 2.67Å
39S85Confident88.4Confident27 Ų2750.6 Ų50.619%0.18930%0.303CS..SBendtrans-78147.5-178.679.30000112.1L35 A36 A42 H281L35-S39 WeakPolarHBondContact O-CB 3.38Å; L35-S39 PolarHBondContact O-N 2.75Å; A36-S39 WeakPolarHBondContact O-CB 3.32Å; A36-S39 PolarHBondContact O-N 3.4Å; A36-S39 VanDerWaalsContact O-N 3.08Å; A36-S39 PolarHBondContact O-OG 3.32Å; S39-A42 PolarHBondContact O-N 3.36Å; S39-A42 PolarHBondContact OG-N 3.03Å; S39-H281 PolarHBondContact O-CE1 2.91Å; S39-H281 PolarHBondContact O-NE2 2.68Å
40G81.4Confident87.5Confident63 Ų6352.6 Ų52.665%0.64932%0.319SS*.SBendtrans-59.5-40.4173.800000114.2H281G40-H281 PolarHBondContact O-CE1 2.97Å
41P84.3Confident86.8Confident69 Ų6959.4 Ų59.445%0.44835%0.354SS..SBendtrans-75-20.8178.8-24.436.7000115.9R43P41-R43 HydrophobicContact CB-CG 3.89Å; P41-R43 PolarHBondContact O-N 3.04Å; P41-R43 VanDerWaalsContact O-N 3.14Å
42A88.8Confident86.3Confident1 Ų159.5 Ų59.51%0.00836%0.359CS..  trans45.344.3-17700000114.6A36 S39 F277 L371A36-A42 WeakPolarHBondContact O-CA 3.26Å; S39-A42 PolarHBondContact O-N 3.36Å; S39-A42 PolarHBondContact OG-N 3.03Å; A42-F277 HydrophobicContact CB-CD2 4.07Å; A42-F277 HydrophobicContact CB-CE2 3.77Å; A42-L371 HydrophobicContact CB-CD2 3.97Å; A42-L371 WeakPolarHBondContact O-CB 3.21Å
43R87.8Confident85.8Confident182 Ų18260.1 Ų60.169%0.68738%0.375SS*.  trans-80.2125.3-178.4-67.2178-176.5-177.51.1110.4P41P41-R43 HydrophobicContact CB-CG 3.89Å; P41-R43 PolarHBondContact O-N 3.04Å; P41-R43 VanDerWaalsContact O-N 3.14Å
44L90.1Very high85.3Confident23 Ų2366.7 Ų66.712%0.1241%0.41CS..SBendtrans-71.3-42.4171.9179.560.7000111.5H32 L33 L370 L371 F374H32-L44 PolarHBondContact NE2-O 3.41Å; L33-L44 HydrophobicContact CD2-CD1 3.65Å; L44-L370 HydrophobicContact CB-CB 4.45Å; L44-L370 HydrophobicContact CD2-CB 4.44Å; L44-L370 HydrophobicContact CD2-CD2 3.85Å; L44-L370 HydrophobicContact CD2-CG 3.77Å; L44-L371 HydrophobicContact CB-CB 4.48Å; L44-L371 HydrophobicContact CD1-CD1 3.97Å; L44-F374 HydrophobicContact CD1-CB 3.98Å; L44-F374 HydrophobicContact CD1-CD2 3.78Å; L44-F374 HydrophobicContact CD1-CG 4.15Å; L44-F374 HydrophobicContact CD2-CB 4.3Å; L44-F374 HydrophobicContact CD2-CD2 4.39Å
45L88.5Confident84.9Confident138 Ų13875.6 Ų75.672%0.72345%0.451SS*.SBendtrans-98.7141.6-176.7-58.1178.2000111.1
46G82.1Confident84.6Confident49 Ų4976.3 Ų76.351%0.50546%0.462SS..SBendtrans101.2169.2-179.300000113.2H32H32-G46 PolarHBondContact CE1-O 3.49Å
47P78.4Confident84.4Confident122 Ų12277.5 Ų77.579%0.79247%0.467SS*.  trans-67.5151.8-18028.8-34.5000111.4
48P77.5Confident84.4Confident39 Ų3982.9 Ų82.925%0.25349%0.487SS..  trans-61148.9171.627.6-34.1000110L35 S50 L51L35-P48 HydrophobicContact CB-CB 4.32Å; L35-P48 HydrophobicContact CD1-CB 4.17Å; L35-P48 HydrophobicContact CD1-CG 4.43Å; P48-S50 PolarHBondContact O-N 2.94Å; P48-S50 VanDerWaalsContact O-N 3.17Å; P48-L51 HydrophobicContact CG-CD2 3.81Å
49A72.8Confident84.7Confident97 Ų9779.7 Ų79.780%0.80248%0.479SS*.SBendtrans-59-30.8-177.700000113.1
50S76.6Confident85.1Confident87 Ų8782.8 Ų82.861%0.60850%0.499SS*.SBendtrans-153.5141174.257.80000109.8P48P48-S50 PolarHBondContact O-N 2.94Å; P48-S50 VanDerWaalsContact O-N 3.17Å
51L82.8Confident85.8Confident142 Ų14289 Ų8974%0.74350%0.503SS*.PPolyproline II helixtrans-79.2132.3168.9-67175000109.5P48P48-L51 HydrophobicContact CG-CD2 3.81Å
52P84.6Confident86.3Confident38 Ų3885.7 Ų85.725%0.24748%0.481CS..PPolyproline II helixtrans-66.2140.9176.928-34.3000110.5L35 A56 L57 L131L35-P52 HydrophobicContact CD1-CG 4.19Å; L35-P52 HydrophobicContact CD2-CG 4.11Å; P52-A56 HydrophobicContact CB-CB 3.9Å; P52-L57 HydrophobicContact CB-CD2 4.33Å; P52-L57 HydrophobicContact CB-CG 4.42Å; P52-L57 HydrophobicContact CG-CD2 3.78Å; P52-L57 HydrophobicContact CG-CG 4.16Å; P52-L131 HydrophobicContact CB-CD2 3.98Å; P52-L131 HydrophobicContact CG-CD2 4.14Å
53G84.8Confident86.7Confident50 Ų5088.3 Ų88.352%0.51550%0.495SS..PPolyproline II helixtrans-66.8162.9166.500000111.6E55 A56 L57G53-E55 PolarHBondContact O-N 3.45Å; G53-E55 VanDerWaalsContact O-N 3.15Å; G53-A56 WeakPolarHBondContact O-CB 3.45Å; G53-A56 PolarHBondContact O-N 3.46Å; G53-L57 PolarHBondContact O-N 3.03Å
54L84.2Confident87.1Confident140 Ų14085.5 Ų85.573%0.73349%0.493SS*.Hα-helixtrans-56.1-32.5179.5-70.2173.8000113A56 L57 W58L54-A56 PolarHBondContact O-N 3.25Å; L54-L57 PolarHBondContact O-N 2.88Å; L54-L57 VanDerWaalsContact O-N 3.09Å; L54-W58 PolarHBondContact O-N 3.36Å
55E85.8Confident87.4Confident189 Ų18988.6 Ų88.688%0.88351%0.509SS*.Hα-helixtrans-63.6-27.8177.2-60.1-177.1175.400113.3G53G53-E55 PolarHBondContact O-N 3.45Å; G53-E55 VanDerWaalsContact O-N 3.15Å
56A87.3Confident87.9Confident47 Ų4782.6 Ų82.639%0.38848%0.477SS..Hα-helixtrans-83.7-21175.600000112.5P52 G53 L54 L131P52-A56 HydrophobicContact CB-CB 3.9Å; G53-A56 WeakPolarHBondContact O-CB 3.45Å; G53-A56 PolarHBondContact O-N 3.46Å; L54-A56 PolarHBondContact O-N 3.25Å; A56-L131 HydrophobicContact CB-CD2 4.42Å
57L90.3Very high88.6Confident28 Ų2884.8 Ų84.815%0.14748%0.477CS..Hα-helixtrans-90-25.2177.8-63.9179.2000112.7P52 G53 L54 L131 P132 F135P52-L57 HydrophobicContact CB-CD2 4.33Å; P52-L57 HydrophobicContact CB-CG 4.42Å; P52-L57 HydrophobicContact CG-CD2 3.78Å; P52-L57 HydrophobicContact CG-CG 4.16Å; G53-L57 PolarHBondContact O-N 3.03Å; L54-L57 PolarHBondContact O-N 2.88Å; L54-L57 VanDerWaalsContact O-N 3.09Å; L57-L131 HydrophobicContact CD2-CD1 3.95Å; L57-L131 HydrophobicContact CD2-CD2 3.99Å; L57-L131 HydrophobicContact CD2-CG 3.82Å; L57-P132 WeakPolarHBondContact O-CA 3.44Å; L57-P132 WeakPolarHBondContact O-CB 3.3Å; L57-F135 HydrophobicContact CB-CB 4.46Å; L57-F135 HydrophobicContact CB-CD2 4.13Å; L57-F135 HydrophobicContact CB-CG 4.11Å; L57-F135 HydrophobicContact CD1-CD2 4.4Å; L57-F135 HydrophobicContact CD1-CE2 4.48Å; L57-F135 VanDerWaalsContact O-CB 3.26Å; L57-F135 WeakPolarHBondContact O-CB 3.35Å; L57-F135 WeakPolarHBondContact O-CD1 3.33Å; L57-F135 WeakPolarHBondContact O-CG 3.34Å
58W92.4Very high89.5Confident115 Ų11581.8 Ų81.844%0.43646%0.462SS..  trans-116.6132.2-175-176.5-104.5000112.5L54 L63 F135 V136 L139L54-W58 PolarHBondContact O-N 3.36Å; W58-L63 HydrophobicContact CH2-CD2 4.03Å; W58-L63 HydrophobicContact CZ2-CD2 4.27Å; W58-F135 AromaticContact CE3-CD1 3.98Å; W58-F135 HydrophobicContact CE3-CD1 3.98Å; W58-F135 AromaticContact CE3-CE1 3.85Å; W58-F135 HydrophobicContact CE3-CE1 3.85Å; W58-F135 HydrophobicContact CZ3-CE1 4.37Å; W58-V136 HydrophobicContact CE3-CG2 4.44Å; W58-V136 HydrophobicContact CZ3-CG2 4.14Å; W58-L139 HydrophobicContact CZ3-CD2 4.37Å
59S93.1Very high90.5Very high27 Ų2781.3 Ų81.319%0.18946%0.455CS..  trans-147.7126.1171.1-179.10000110.4R61 A62 L63S59-R61 PolarHBondContact O-N 3.48Å; S59-R61 PolarHBondContact OG-N 3.25Å; S59-A62 WeakPolarHBondContact O-CB 3.34Å; S59-A62 PolarHBondContact O-N 3.02Å; S59-L63 PolarHBondContact O-N 2.82Å; S59-L63 VanDerWaalsContact O-N 3.08Å
60P94.5Very high91.6Very high92 Ų9278.3 Ų78.360%0.59743%0.425SS*.Hα-helixtrans-56.6-32.1172.5-25.934.5000112.8L63 L64P60-L63 PolarHBondContact O-N 3.15Å; P60-L64 PolarHBondContact O-N 3.1Å
61R94.5Very high92.6Very high193 Ų19376.1 Ų76.173%0.72842%0.417SS*.Hα-helixtrans-66.8-40.7175.2-63.6-178.2-178.6171.90.3111.4S59 L63 L64 L65 M129S59-R61 PolarHBondContact O-N 3.48Å; S59-R61 PolarHBondContact OG-N 3.25Å; R61-L63 VanDerWaalsContact C-N 3.35Å; R61-L64 PolarHBondContact O-N 2.79Å; R61-L65 WeakPolarHBondContact O-CB 3.42Å; R61-L65 VanDerWaalsContact O-CG 3.29Å; R61-L65 WeakPolarHBondContact O-CG 3.47Å; R61-L65 PolarHBondContact O-N 2.89Å; R61-M129 HydrophobicContact CB-CE 3.76Å
62A96Very high93.3Very high0 Ų072 Ų720%040%0.395CS..Hα-helixtrans-64.6-41.2176.600000111.2S59 L65 W66 M129 P132 L133 V136S59-A62 WeakPolarHBondContact O-CB 3.34Å; S59-A62 PolarHBondContact O-N 3.02Å; A62-L65 PolarHBondContact O-N 3.43Å; A62-W66 VanDerWaalsContact O-CB 3.27Å; A62-W66 WeakPolarHBondContact O-CB 3.46Å; A62-W66 PolarHBondContact O-N 3.38Å; A62-M129 HydrophobicContact CB-CE 3.81Å; A62-P132 HydrophobicContact CB-CB 3.89Å; A62-P132 HydrophobicContact CB-CG 4.28Å; A62-L133 HydrophobicContact CB-CD2 3.98Å; A62-L133 HydrophobicContact CB-CG 4.15Å; A62-L133 WeakPolarHBondContact O-CD2 3.27Å; A62-V136 HydrophobicContact CB-CG2 4.47Å
63L96.6Very high93.9Very high57 Ų5770.2 Ų70.230%0.29838%0.383SS..Hα-helixtrans-60.1-48173.9177.962.1000111.9W58 S59 P60 R61 L65 W66 L67 V136W58-L63 HydrophobicContact CH2-CD2 4.03Å; W58-L63 HydrophobicContact CZ2-CD2 4.27Å; S59-L63 PolarHBondContact O-N 2.82Å; S59-L63 VanDerWaalsContact O-N 3.08Å; P60-L63 PolarHBondContact O-N 3.15Å; R61-L63 VanDerWaalsContact C-N 3.35Å; L63-L65 PolarHBondContact O-N 2.89Å; L63-W66 PolarHBondContact O-N 2.8Å; L63-L67 HydrophobicContact CD1-CD1 3.98Å; L63-L67 HydrophobicContact CD1-CG 4.06Å; L63-L67 HydrophobicContact CG-CD1 4.05Å; L63-L67 HydrophobicContact CG-CG 4.48Å; L63-L67 WeakPolarHBondContact O-CG 3.46Å; L63-L67 PolarHBondContact O-N 2.97Å; L63-V136 HydrophobicContact CB-CG2 4.32Å; L63-V136 HydrophobicContact CD1-CG1 3.73Å
64L97Very high94.5Very high123 Ų12368.9 Ų68.964%0.64437%0.368SS*.Hα-helixtrans-61.5-45.2178.7-178.863.5000111.9P60 R61 W66 L67 A68P60-L64 PolarHBondContact O-N 3.1Å; R61-L64 PolarHBondContact O-N 2.79Å; L64-W66 VanDerWaalsContact C-N 3.34Å; L64-W66 PolarHBondContact O-N 3.3Å; L64-L67 PolarHBondContact O-N 2.94Å; L64-A68 VanDerWaalsContact O-CB 3.27Å; L64-A68 WeakPolarHBondContact O-CB 3.35Å; L64-A68 PolarHBondContact O-N 3.03Å
65L96.3Very high95Very high88 Ų8865 Ų6546%0.46136%0.355SS..Hα-helixtrans-62.1-42.2177.2-73.6174.6000111.8R61 A62 L63 A68 W69 M129 L133R61-L65 WeakPolarHBondContact O-CB 3.42Å; R61-L65 VanDerWaalsContact O-CG 3.29Å; R61-L65 WeakPolarHBondContact O-CG 3.47Å; R61-L65 PolarHBondContact O-N 2.89Å; A62-L65 PolarHBondContact O-N 3.43Å; L63-L65 PolarHBondContact O-N 2.89Å; L65-A68 PolarHBondContact O-N 3.09Å; L65-W69 VanDerWaalsContact O-CB 3.29Å; L65-W69 WeakPolarHBondContact O-CB 3.25Å; L65-W69 PolarHBondContact O-N 3.08Å; L65-M129 HydrophobicContact CD1-CE 3.69Å; L65-M129 HydrophobicContact CD1-SD 3.84Å; L65-L133 HydrophobicContact CB-CD2 4.3Å
66W97.6Very high95.4Very high11 Ų1156.6 Ų56.64%0.04232%0.317CS..Hα-helixtrans-63.5-45.8177.1177.9-106.6000112.3A62 L63 L64 W69 L70 L133 V136 A137 T140 I264A62-W66 VanDerWaalsContact O-CB 3.27Å; A62-W66 WeakPolarHBondContact O-CB 3.46Å; A62-W66 PolarHBondContact O-N 3.38Å; L63-W66 PolarHBondContact O-N 2.8Å; L64-W66 VanDerWaalsContact C-N 3.34Å; L64-W66 PolarHBondContact O-N 3.3Å; W66-W69 WeakPolarHBondContact O-CB 3.39Å; W66-W69 PolarHBondContact O-N 3.29Å; W66-L70 HydrophobicContact CD2-CG 4.44Å; W66-L70 HydrophobicContact CH2-CD2 4.38Å; W66-L70 HydrophobicContact CZ2-CD1 4.04Å; W66-L70 HydrophobicContact CZ2-CD2 4.01Å; W66-L70 HydrophobicContact CZ2-CG 4.17Å; W66-L70 WeakPolarHBondContact O-CG 3.43Å; W66-L70 PolarHBondContact O-N 3.33Å; W66-L133 HydrophobicContact CB-CD2 4.34Å; W66-V136 HydrophobicContact CB-CG1 3.79Å; W66-V136 VanDerWaalsContact CD1-CG1 3.41Å; W66-V136 HydrophobicContact CG-CG1 3.64Å; W66-A137 HydrophobicContact CD2-CB 4.43Å; W66-A137 HydrophobicContact CE3-CB 4.31Å; W66-A137 HydrophobicContact CH2-CB 3.65Å; W66-A137 HydrophobicContact CZ2-CB 3.76Å; W66-A137 HydrophobicContact CZ3-CB 3.93Å; W66-T140 HydrophobicContact CZ2-CG2 4.47Å; W66-T140 PolarHBondContact NE1-OG1 2.87Å; W66-I264 HydrophobicContact CH2-CB 4.02Å; W66-I264 HydrophobicContact CH2-CG1 4.37Å; W66-I264 VanDerWaalsContact CH2-O 3.32Å; W66-I264 WeakPolarHBondContact CH2-O 3.25Å; W66-I264 HydrophobicContact CZ2-CB 4.18Å; W66-I264 HydrophobicContact CZ2-CD1 4.27Å; W66-I264 HydrophobicContact CZ2-CG1 4.2Å
67L97.7Very high95.7Very high96 Ų9654.4 Ų54.450%0.50330%0.298SS..Hα-helixtrans-65.5-40.2176.7-68.4175.7000111.8L63 L64 W69 L70 G71L63-L67 HydrophobicContact CD1-CD1 3.98Å; L63-L67 HydrophobicContact CD1-CG 4.06Å; L63-L67 HydrophobicContact CG-CD1 4.05Å; L63-L67 HydrophobicContact CG-CG 4.48Å; L63-L67 WeakPolarHBondContact O-CG 3.46Å; L63-L67 PolarHBondContact O-N 2.97Å; L64-L67 PolarHBondContact O-N 2.94Å; L67-W69 VanDerWaalsContact C-N 3.32Å; L67-W69 PolarHBondContact O-N 3.49Å; L67-L70 PolarHBondContact O-N 3.48Å; L67-G71 PolarHBondContact O-N 2.93Å
68A97.1Very high95.7Very high58 Ų5856.3 Ų56.348%0.47931%0.308SS..Hα-helixtrans-62.8-40174.200000111.5L64 L65 G71 L72L64-A68 VanDerWaalsContact O-CB 3.27Å; L64-A68 WeakPolarHBondContact O-CB 3.35Å; L64-A68 PolarHBondContact O-N 3.03Å; L65-A68 PolarHBondContact O-N 3.09Å; A68-G71 PolarHBondContact O-N 2.74Å; A68-L72 VanDerWaalsContact O-CB 3.29Å; A68-L72 WeakPolarHBondContact O-CB 3.49Å; A68-L72 PolarHBondContact O-N 2.85Å
69W97.7Very high95.6Very high29 Ų2953.8 Ų53.811%0.1130%0.303CS..Hα-helixtrans-62.5-51.4175.3175-113.7000112.2L65 W66 L67 G71 L72 Q73 T109 P196 I199 G200 L203L65-W69 VanDerWaalsContact O-CB 3.29Å; L65-W69 WeakPolarHBondContact O-CB 3.25Å; L65-W69 PolarHBondContact O-N 3.08Å; W66-W69 WeakPolarHBondContact O-CB 3.39Å; W66-W69 PolarHBondContact O-N 3.29Å; L67-W69 VanDerWaalsContact C-N 3.32Å; L67-W69 PolarHBondContact O-N 3.49Å; W69-G71 VanDerWaalsContact C-N 3.32Å; W69-G71 PolarHBondContact O-N 3.1Å; W69-L72 HydrophobicContact CE3-CD2 4.49Å; W69-L72 HydrophobicContact CZ3-CD2 4.46Å; W69-L72 PolarHBondContact O-N 3.3Å; W69-Q73 HydrophobicContact CD2-CG 4.12Å; W69-Q73 HydrophobicContact CE3-CG 4.39Å; W69-Q73 HydrophobicContact CH2-CG 4.03Å; W69-Q73 HydrophobicContact CZ2-CG 3.67Å; W69-Q73 HydrophobicContact CZ3-CG 4.36Å; W69-Q73 VanDerWaalsContact CZ3-NE2 3.3Å; W69-Q73 WeakPolarHBondContact O-CG 3.38Å; W69-Q73 PolarHBondContact O-N 3.32Å; W69-T109 HydrophobicContact CH2-CG2 3.88Å; W69-T109 HydrophobicContact CZ3-CG2 3.69Å; W69-P196 PolarHBondContact NE1-O 3.24Å; W69-P196 VanDerWaalsContact NE1-O 3.09Å; W69-I199 HydrophobicContact CH2-CB 4.15Å; W69-I199 HydrophobicContact CH2-CG2 3.72Å; W69-I199 HydrophobicContact CZ2-CB 4.14Å; W69-I199 HydrophobicContact CZ2-CG2 4.23Å; W69-G200 VanDerWaalsContact CZ2-CA 3.44Å; W69-G200 VanDerWaalsContact CZ2-N 3.33Å; W69-L203 HydrophobicContact CE3-CD2 3.93Å; W69-L203 HydrophobicContact CH2-CD2 4.13Å; W69-L203 HydrophobicContact CZ3-CD2 3.64Å
70L97.7Very high94.6Very high35 Ų3558 Ų5818%0.18333%0.33CS..Hα-helixtrans-60.4-43.1176.6-70.9-176.8000111.6W66 L67 Q73 A74 T140 P196W66-L70 HydrophobicContact CD2-CG 4.44Å; W66-L70 HydrophobicContact CH2-CD2 4.38Å; W66-L70 HydrophobicContact CZ2-CD1 4.04Å; W66-L70 HydrophobicContact CZ2-CD2 4.01Å; W66-L70 HydrophobicContact CZ2-CG 4.17Å; W66-L70 WeakPolarHBondContact O-CG 3.43Å; W66-L70 PolarHBondContact O-N 3.33Å; L67-L70 PolarHBondContact O-N 3.48Å; L70-Q73 PolarHBondContact O-N 3.41Å; L70-A74 VanDerWaalsContact O-CB 3.23Å; L70-A74 WeakPolarHBondContact O-CB 3.3Å; L70-A74 PolarHBondContact O-N 3.03Å; L70-T140 HydrophobicContact CD1-CG2 4.19Å; L70-P196 HydrophobicContact CD2-CB 3.64Å; L70-P196 HydrophobicContact CD2-CG 4.25Å
71G97.3Very high93.3Very high41 Ų4157.6 Ų57.642%0.42333%0.334SS..Hα-helixtrans-62.3-43.9177.100000112.7L67 A68 W69 A74 A75L67-G71 PolarHBondContact O-N 2.93Å; A68-G71 PolarHBondContact O-N 2.74Å; W69-G71 VanDerWaalsContact C-N 3.32Å; W69-G71 PolarHBondContact O-N 3.1Å; G71-A74 PolarHBondContact O-N 2.91Å; G71-A75 WeakPolarHBondContact O-CB 3.25Å; G71-A75 PolarHBondContact O-N 3.25Å
72L97.2Very high92.4Very high55 Ų5552 Ų5229%0.28831%0.313SS..Hα-helixtrans-60.9-51.3175.2174.462.6000111A68 W69 A74 A75 L76 L112A68-L72 VanDerWaalsContact O-CB 3.29Å; A68-L72 WeakPolarHBondContact O-CB 3.49Å; A68-L72 PolarHBondContact O-N 2.85Å; W69-L72 HydrophobicContact CE3-CD2 4.49Å; W69-L72 HydrophobicContact CZ3-CD2 4.46Å; W69-L72 PolarHBondContact O-N 3.3Å; L72-A74 VanDerWaalsContact C-N 3.32Å; L72-A74 PolarHBondContact O-N 3.5Å; L72-A75 PolarHBondContact O-N 3.48Å; L72-L76 HydrophobicContact CD1-CD1 4.18Å; L72-L76 HydrophobicContact CD1-CG 4.21Å; L72-L76 HydrophobicContact CG-CD1 4.19Å; L72-L76 WeakPolarHBondContact O-CG 3.29Å; L72-L76 PolarHBondContact O-N 3.35Å; L72-L112 HydrophobicContact CD1-CD1 3.79Å
73Q97.3Very high92Very high0 Ų057.8 Ų57.80%034%0.338CS..Hα-helixtrans-63.8-38.6-179.4-68.2-53.3-40.800111.8W69 L70 L76 Y77 T109 F191 R195W69-Q73 HydrophobicContact CD2-CG 4.12Å; W69-Q73 HydrophobicContact CE3-CG 4.39Å; W69-Q73 HydrophobicContact CH2-CG 4.03Å; W69-Q73 HydrophobicContact CZ2-CG 3.67Å; W69-Q73 HydrophobicContact CZ3-CG 4.36Å; W69-Q73 VanDerWaalsContact CZ3-NE2 3.3Å; W69-Q73 WeakPolarHBondContact O-CG 3.38Å; W69-Q73 PolarHBondContact O-N 3.32Å; L70-Q73 PolarHBondContact O-N 3.41Å; Q73-L76 PolarHBondContact O-N 2.93Å; Q73-Y77 WeakPolarHBondContact O-CB 3.17Å; Q73-Y77 PolarHBondContact O-N 3.45Å; Q73-T109 PolarHBondContact NE2-OG1 3.37Å; Q73-F191 HydrophobicContact CB-CE2 4.03Å; Q73-F191 HydrophobicContact CB-CZ 3.96Å; Q73-R195 HydrophobicContact CB-CB 4.26Å
74A96.1Very high91.7Very high23 Ų2358.8 Ų58.819%0.1935%0.346CS..Hα-helixtrans-64-43.117400000111.6L70 G71 L72 L76 Y77 L78 F186 F191L70-A74 VanDerWaalsContact O-CB 3.23Å; L70-A74 WeakPolarHBondContact O-CB 3.3Å; L70-A74 PolarHBondContact O-N 3.03Å; G71-A74 PolarHBondContact O-N 2.91Å; L72-A74 VanDerWaalsContact C-N 3.32Å; L72-A74 PolarHBondContact O-N 3.5Å; A74-L76 PolarHBondContact O-N 3.31Å; A74-Y77 WeakPolarHBondContact O-CB 3.27Å; A74-Y77 PolarHBondContact O-N 3.28Å; A74-L78 VanDerWaalsContact O-CG 3.23Å; A74-L78 WeakPolarHBondContact O-CG 3.28Å; A74-L78 PolarHBondContact O-N 2.87Å; A74-L78 VanDerWaalsContact O-N 3.08Å; A74-F186 HydrophobicContact CB-CE2 4.09Å; A74-F186 HydrophobicContact CB-CZ 4.43Å; A74-F191 HydrophobicContact CB-CE2 4.29Å; A74-F191 HydrophobicContact CB-CZ 4.12Å
75A95.4Very high91.4Very high57 Ų5753.4 Ų53.447%0.47132%0.32SS..Hα-helixtrans-61.4-43.9175.800000111.7G71 L72 L78 L79G71-A75 WeakPolarHBondContact O-CB 3.25Å; G71-A75 PolarHBondContact O-N 3.25Å; L72-A75 PolarHBondContact O-N 3.48Å; A75-L78 PolarHBondContact O-N 3.04Å; A75-L79 PolarHBondContact O-N 3.49Å
76L94.8Very high91.1Very high14 Ų1454.4 Ų54.47%0.07332%0.322CS..Hα-helixtrans-63.8-40.1175.9-67.4176.9000112L72 Q73 A74 L78 L79 N101 A105 L108 T109L72-L76 HydrophobicContact CD1-CD1 4.18Å; L72-L76 HydrophobicContact CD1-CG 4.21Å; L72-L76 HydrophobicContact CG-CD1 4.19Å; L72-L76 WeakPolarHBondContact O-CG 3.29Å; L72-L76 PolarHBondContact O-N 3.35Å; Q73-L76 PolarHBondContact O-N 2.93Å; A74-L76 PolarHBondContact O-N 3.31Å; L76-L78 PolarHBondContact O-N 3.38Å; L76-L79 HydrophobicContact CB-CD1 4.46Å; L76-L79 HydrophobicContact CD2-CD1 3.76Å; L76-L79 WeakPolarHBondContact O-CB 3.31Å; L76-L79 WeakPolarHBondContact O-CG 3.35Å; L76-L79 PolarHBondContact O-N 3.32Å; L76-N101 PolarHBondContact O-ND2 2.77Å; L76-A105 HydrophobicContact CB-CB 4.01Å; L76-A105 HydrophobicContact CD1-CB 4.16Å; L76-L108 HydrophobicContact CD2-CB 4.09Å; L76-L108 HydrophobicContact CD2-CD1 3.9Å; L76-T109 WeakPolarHBondContact CD1-OG1 3.27Å
77Y93.1Very high90.8Very high1 Ų154 Ų540%0.00432%0.321CS..Hα-helixtrans-59.5-34.9174.5179.2-95000112.3Q73 A74 P99 F186 Y190 F191 R195Q73-Y77 WeakPolarHBondContact O-CB 3.17Å; Q73-Y77 PolarHBondContact O-N 3.45Å; A74-Y77 WeakPolarHBondContact O-CB 3.27Å; A74-Y77 PolarHBondContact O-N 3.28Å; Y77-P99 HydrophobicContact CD2-CG 4.02Å; Y77-P99 HydrophobicContact CE1-CG 3.89Å; Y77-P99 HydrophobicContact CE2-CG 3.34Å; Y77-P99 VanDerWaalsContact OH-CD 3.28Å; Y77-P99 WeakPolarHBondContact OH-CD 3.06Å; Y77-P99 VanDerWaalsContact OH-CG 3.3Å; Y77-P99 WeakPolarHBondContact OH-CG 3.4Å; Y77-F186 AromaticContact CD1-CD2 3.83Å; Y77-F186 HydrophobicContact CD1-CD2 3.83Å; Y77-F186 AromaticContact CD1-CE2 3.69Å; Y77-F186 HydrophobicContact CD1-CE2 3.69Å; Y77-F186 HydrophobicContact CD1-CZ 4.3Å; Y77-F186 AromaticContact CE1-CD2 3.96Å; Y77-F186 HydrophobicContact CE1-CD2 3.96Å; Y77-F186 HydrophobicContact CE1-CE2 4.17Å; Y77-F186 HydrophobicContact CE1-CG 4.21Å; Y77-F186 HydrophobicContact CG-CE2 4.44Å; Y77-Y190 AromaticContact CE2-CD1 3.72Å; Y77-Y190 HydrophobicContact CE2-CD1 3.72Å; Y77-Y190 AromaticContact CE2-CE1 3.9Å; Y77-Y190 HydrophobicContact CE2-CE1 3.9Å; Y77-F191 HydrophobicContact CD1-CD2 4.46Å; Y77-F191 AromaticContact CD2-CD2 3.97Å; Y77-F191 HydrophobicContact CD2-CD2 3.97Å; Y77-F191 HydrophobicContact CE2-CB 4.46Å; Y77-F191 AromaticContact CG-CD2 3.87Å; Y77-F191 HydrophobicContact CG-CD2 3.87Å; Y77-R195 HydrophobicContact CD2-CG 4.37Å
78L91.3Very high90.3Very high68 Ų6852.7 Ų52.736%0.35631%0.313SS..THydrogen-bonded Turntrans-86.3-1.3-177.2-61170.7000114.6A74 A75 L76 R82 F185 F186A74-L78 VanDerWaalsContact O-CG 3.23Å; A74-L78 WeakPolarHBondContact O-CG 3.28Å; A74-L78 PolarHBondContact O-N 2.87Å; A74-L78 VanDerWaalsContact O-N 3.08Å; A75-L78 PolarHBondContact O-N 3.04Å; L76-L78 PolarHBondContact O-N 3.38Å; L78-R82 VanDerWaalsContact C-NH1 3.32Å; L78-R82 PolarHBondContact O-NH1 3.45Å; L78-F185 HydrophobicContact CD2-CD2 3.76Å; L78-F185 HydrophobicContact CD2-CE2 3.24Å; L78-F185 HydrophobicContact CD2-CZ 4.21Å; L78-F185 HydrophobicContact CG-CE2 4.47Å; L78-F186 HydrophobicContact CD1-CD2 4.48Å; L78-F186 HydrophobicContact CD2-CD2 3.87Å; L78-F186 HydrophobicContact CD2-CE2 4.49Å; L78-F186 HydrophobicContact CG-CD2 4.37Å
79L88.3Confident89.7Confident61 Ų6154 Ų5432%0.31931%0.309SS..  trans-54.4136.4-179.5-75.1171000112.8A75 L76 R82 L108A75-L79 PolarHBondContact O-N 3.49Å; L76-L79 HydrophobicContact CB-CD1 4.46Å; L76-L79 HydrophobicContact CD2-CD1 3.76Å; L76-L79 WeakPolarHBondContact O-CB 3.31Å; L76-L79 WeakPolarHBondContact O-CG 3.35Å; L76-L79 PolarHBondContact O-N 3.32Å; L79-R82 VanDerWaalsContact O-CD 3.3Å; L79-R82 WeakPolarHBondContact O-CD 3.2Å; L79-R82 PolarHBondContact O-NH1 2.91Å; L79-L108 HydrophobicContact CD1-CD1 3.8Å
80P73.1Confident89.2Confident117 Ų11754.8 Ų54.876%0.7632%0.315SS*.SBendtrans-76.9-27.7-171.227.1-33.7000114.8R82P80-R82 PolarHBondContact O-N 2.97Å
81A66.3Low88.3Confident83 Ų8360.4 Ų60.469%0.68634%0.34SS*.SBendtrans-83.874.6-177.900000111.7
82R77Confident87.5Confident75 Ų7562.6 Ų62.628%0.28334%0.342SS..  trans-136.5146.2-171.161.4-178.2-176.6-122.37.1113.9L78 L79 P80 V84 P99 N101L78-R82 VanDerWaalsContact C-NH1 3.32Å; L78-R82 PolarHBondContact O-NH1 3.45Å; L79-R82 VanDerWaalsContact O-CD 3.3Å; L79-R82 WeakPolarHBondContact O-CD 3.2Å; L79-R82 PolarHBondContact O-NH1 2.91Å; P80-R82 PolarHBondContact O-N 2.97Å; R82-V84 HydrophobicContact CG-CG2 4.39Å; R82-P99 HydrophobicContact CG-CB 4.47Å; R82-N101 HydrophobicContact CB-CB 4.23Å
83K86.8Confident87Confident121 Ų12167.1 Ų67.153%0.52636%0.36SS..EExtended strand (participates in β ladder)trans-68.3142162180-177.9170.8-165.20108I100 E242K83-I100 HydrophobicContact CB-CB 4.24Å; K83-I100 HydrophobicContact CG-CB 4.44Å; K83-I100 PolarHBondContact O-N 2.86Å; K83-E242 IonicContact NZ-OE2 3.15Å; K83-E242 PolarHBondContact NZ-OE2 3.46Å
84V90.3Very high86.5Confident78 Ų7869.2 Ų69.247%0.47337%0.374SS..EExtended strand (participates in β ladder)trans-116.6131.7173.4179.50000108R82 R97 Y98R82-V84 HydrophobicContact CG-CG2 4.39Å; V84-R97 HydrophobicContact CG1-CB 3.85Å; V84-R97 HydrophobicContact CG1-CG 4.3Å; V84-Y98 WeakPolarHBondContact CA-O 3.43Å
85A90.7Very high86.3Confident10 Ų1073.3 Ų73.38%0.08339%0.385CS..EExtended strand (participates in β ladder)trans-116.2155.4173.200000110.8Y98 I100 E242 L245A85-Y98 PolarHBondContact N-O 3.33Å; A85-Y98 PolarHBondContact O-N 3.41Å; A85-I100 HydrophobicContact CB-CD1 3.84Å; A85-I100 HydrophobicContact CB-CG1 3.63Å; A85-E242 HydrophobicContact CB-CG 3.86Å; A85-L245 HydrophobicContact CB-CD1 4.05Å
86E91.3Very high86.2Confident109 Ų10972.3 Ų72.351%0.50937%0.371SS..EExtended strand (participates in β ladder)trans-95136.6175.1-60.8-166.1151.700110.2R95 R97E86-R95 HydrophobicContact CB-CB 4.49Å; E86-R97 HydrophobicContact CG-CG 4.47Å; E86-R97 IonicContact OE1-NE 2.82Å; E86-R97 IonicContact OE1-NH2 3.74Å
87G89.7Confident86.1Confident3 Ų379.5 Ų79.53%0.03140%0.397CS..EExtended strand (participates in β ladder)trans-73.4-173173.500000113R95 L96G87-R95 PolarHBondContact O-NH1 3.3Å; G87-R95 VanDerWaalsContact O-NH1 3.09Å; G87-L96 PolarHBondContact N-O 2.91Å
88Q87.1Confident86Confident68 Ų6879.6 Ų79.632%0.31840%0.398SS..EExtended strand (participates in β ladder)trans-66.4156.1170.4-67.3-59.3-60.600111.5L90 T251Q88-L90 PolarHBondContact O-N 2.83Å; Q88-T251 HydrophobicContact CB-CG2 4.15Å; Q88-T251 HydrophobicContact CG-CG2 3.77Å
89E86.4Confident86.1Confident87 Ų8776.7 Ų76.741%0.40738%0.383SS..EExtended strand (participates in β ladder)trans-66.4126.8173.1-169.7173.9120.500109.7K93 R95E89-K93 HydrophobicContact CG-CD 4.23Å; E89-K93 WeakPolarHBondContact OE1-CD 3.45Å; E89-K93 IonicContact OE1-NZ 2.78Å; E89-K93 PolarHBondContact OE1-NZ 2.85Å; E89-R95 IonicContact OE2-NH2 2.94Å; E89-R95 PolarHBondContact OE2-NH2 3.19Å
90L85.3Confident86.3Confident44 Ų4474.9 Ų74.923%0.2337%0.373CS..PPolyproline II helixtrans-81.7172.8175.2-61.5-177.4000111Q88 D92 K93 S94 L96 L179Q88-L90 PolarHBondContact O-N 2.83Å; L90-D92 WeakPolarHBondContact CB-OD1 3.26Å; L90-D92 PolarHBondContact O-N 2.87Å; L90-K93 PolarHBondContact O-N 3.46Å; L90-S94 PolarHBondContact N-O 3.07Å; L90-L96 HydrophobicContact CD1-CD1 3.9Å; L90-L96 HydrophobicContact CD1-CD2 4.43Å; L90-L96 HydrophobicContact CD1-CG 3.86Å; L90-L179 HydrophobicContact CD2-CD2 4.12Å
91E79.8Confident87.3Confident153 Ų15369.5 Ų69.572%0.71534%0.338SS*.THydrogen-bonded Turntrans-59-33.1179.1-64.1-168.6165.400112.7K93E91-K93 PolarHBondContact O-N 3.09Å
92D81.3Confident88.7Confident88 Ų8865.5 Ų65.547%0.47131%0.306SS..THydrogen-bonded Turntrans-80.29.5176.971.8-6.2000114L90 S94L90-D92 WeakPolarHBondContact CB-OD1 3.26Å; L90-D92 PolarHBondContact O-N 2.87Å; D92-S94 VanDerWaalsContact CG-OG 3.27Å; D92-S94 PolarHBondContact O-N 3.1Å; D92-S94 VanDerWaalsContact O-N 3.15Å; D92-S94 WeakPolarHBondContact OD1-CB 3.24Å; D92-S94 PolarHBondContact OD1-N 3.14Å; D92-S94 PolarHBondContact OD1-OG 3.35Å; D92-S94 PolarHBondContact OD2-OG 2.85Å
93K85.3Confident89.5Confident150 Ų15065.3 Ų65.365%0.65231%0.307SS*.SBendtrans66.81.6-176.6-54.3-58-169.7-176.80115.4E89 L90 E91E89-K93 HydrophobicContact CG-CD 4.23Å; E89-K93 WeakPolarHBondContact OE1-CD 3.45Å; E89-K93 IonicContact OE1-NZ 2.78Å; E89-K93 PolarHBondContact OE1-NZ 2.85Å; L90-K93 PolarHBondContact O-N 3.46Å; E91-K93 PolarHBondContact O-N 3.09Å
94S87.9Confident89.9Confident43 Ų4364 Ų6430%0.30130%0.303SS..  trans-76.5161.2174.978.10000111.5L90 D92L90-S94 PolarHBondContact N-O 3.07Å; D92-S94 VanDerWaalsContact CG-OG 3.27Å; D92-S94 PolarHBondContact O-N 3.1Å; D92-S94 VanDerWaalsContact O-N 3.15Å; D92-S94 WeakPolarHBondContact OD1-CB 3.24Å; D92-S94 PolarHBondContact OD1-N 3.14Å; D92-S94 PolarHBondContact OD1-OG 3.35Å; D92-S94 PolarHBondContact OD2-OG 2.85Å
95R91.6Very high90.2Very high109 Ų10960.3 Ų60.341%0.41128%0.28SS..EExtended strand (participates in β ladder)trans-126.3126.1172.6-70.8-179.8-177.9-95.2-2.1109.5E86 G87 E89E86-R95 HydrophobicContact CB-CB 4.49Å; G87-R95 PolarHBondContact O-NH1 3.3Å; G87-R95 VanDerWaalsContact O-NH1 3.09Å; E89-R95 IonicContact OE2-NH2 2.94Å; E89-R95 PolarHBondContact OE2-NH2 3.19Å
96L92.3Very high90.5Very high36 Ų3660.7 Ų60.719%0.18828%0.281CS..EExtended strand (participates in β ladder)trans-78.6142.7176.1-65.7175.4000110.6G87 L90 Y98 N180G87-L96 PolarHBondContact N-O 2.91Å; L90-L96 HydrophobicContact CD1-CD1 3.9Å; L90-L96 HydrophobicContact CD1-CD2 4.43Å; L90-L96 HydrophobicContact CD1-CG 3.86Å; L96-Y98 HydrophobicContact CB-CD2 4.45Å; L96-Y98 HydrophobicContact CB-CE2 3.61Å; L96-Y98 WeakPolarHBondContact O-CD2 3.26Å; L96-N180 HydrophobicContact CD1-CB 3.77Å
97R92.6Very high90.7Very high165 Ų16558.5 Ų58.562%0.62328%0.275SS*.EExtended strand (participates in β ladder)trans-97.9139.5176.3-68.6-178.7176.3175.30.7110.5V84 E86 R182V84-R97 HydrophobicContact CG1-CB 3.85Å; V84-R97 HydrophobicContact CG1-CG 4.3Å; E86-R97 HydrophobicContact CG-CG 4.47Å; E86-R97 IonicContact OE1-NE 2.82Å; E86-R97 IonicContact OE1-NH2 3.74Å; R97-R182 PolarHBondContact O-NH1 3.43Å; R97-R182 VanDerWaalsContact O-NH1 3.12Å
98Y92.8Very high91.1Very high4 Ų461.5 Ų61.52%0.01629%0.29CS..EExtended strand (participates in β ladder)trans-130.1134.6-175.4-65.5-93000111.7V84 A85 L96 R182 D187 Y190 L245V84-Y98 WeakPolarHBondContact CA-O 3.43Å; A85-Y98 PolarHBondContact N-O 3.33Å; A85-Y98 PolarHBondContact O-N 3.41Å; L96-Y98 HydrophobicContact CB-CD2 4.45Å; L96-Y98 HydrophobicContact CB-CE2 3.61Å; L96-Y98 WeakPolarHBondContact O-CD2 3.26Å; Y98-R182 PolarHBondContact OH-NH2 3.44Å; Y98-D187 HydrophobicContact CE1-CB 4.18Å; Y98-D187 WeakPolarHBondContact CE1-OD2 3.1Å; Y98-Y190 AromaticContact CD1-CD1 3.66Å; Y98-Y190 HydrophobicContact CD1-CD1 3.66Å; Y98-Y190 AromaticContact CD1-CD2 3.91Å; Y98-Y190 HydrophobicContact CD1-CD2 3.91Å; Y98-Y190 HydrophobicContact CD1-CE1 4.06Å; Y98-Y190 HydrophobicContact CD1-CE2 4.27Å; Y98-Y190 AromaticContact CD1-CG 3.56Å; Y98-Y190 HydrophobicContact CD1-CG 3.56Å; Y98-Y190 HydrophobicContact CE1-CD1 4.38Å; Y98-Y190 HydrophobicContact CE1-CD2 4.21Å; Y98-Y190 AromaticContact CE1-CG 3.89Å; Y98-Y190 HydrophobicContact CE1-CG 3.89Å; Y98-L245 HydrophobicContact CD1-CD2 3.68Å; Y98-L245 HydrophobicContact CD2-CD1 3.92Å; Y98-L245 HydrophobicContact CD2-CD2 3.6Å; Y98-L245 HydrophobicContact CD2-CG 4.39Å; Y98-L245 HydrophobicContact CE1-CD2 3.93Å; Y98-L245 HydrophobicContact CE2-CD2 3.89Å; Y98-L245 HydrophobicContact CG-CD1 4.15Å; Y98-L245 HydrophobicContact CG-CD2 3.48Å; Y98-L245 VanDerWaalsContact CG-CD2 3.48Å; Y98-L245 HydrophobicContact CG-CG 4.48Å
99P92.6Very high91.5Very high7 Ų758.5 Ų58.55%0.04528%0.276CS..EExtended strand (participates in β ladder)trans-74.3123.7173.132-34.6000111.2Y77 R82 Y190Y77-P99 HydrophobicContact CD2-CG 4.02Å; Y77-P99 HydrophobicContact CE1-CG 3.89Å; Y77-P99 HydrophobicContact CE2-CG 3.34Å; Y77-P99 VanDerWaalsContact OH-CD 3.28Å; Y77-P99 WeakPolarHBondContact OH-CD 3.06Å; Y77-P99 VanDerWaalsContact OH-CG 3.3Å; Y77-P99 WeakPolarHBondContact OH-CG 3.4Å; R82-P99 HydrophobicContact CG-CB 4.47Å; P99-Y190 HydrophobicContact CG-CE1 4.46Å; P99-Y190 PolarHBondContact O-OH 2.62Å
100I93.1Very high92Very high22 Ų2257 Ų5711%0.11328%0.279CS..EExtended strand (participates in β ladder)trans-103.388.7177.9-47.8-55.3000108.5K83 A85 Y190 E241 L245K83-I100 HydrophobicContact CB-CB 4.24Å; K83-I100 HydrophobicContact CG-CB 4.44Å; K83-I100 PolarHBondContact O-N 2.86Å; A85-I100 HydrophobicContact CB-CD1 3.84Å; A85-I100 HydrophobicContact CB-CG1 3.63Å; I100-Y190 VanDerWaalsContact CD1-OH 3.24Å; I100-Y190 WeakPolarHBondContact CD1-OH 3.07Å; I100-E241 WeakPolarHBondContact CA-OE2 3.42Å; I100-E241 HydrophobicContact CD1-CG 4.13Å; I100-E241 HydrophobicContact CG2-CB 4.24Å; I100-E241 HydrophobicContact CG2-CG 4.14Å; I100-E241 WeakPolarHBondContact CG2-OE2 3.27Å; I100-L245 HydrophobicContact CD1-CD1 4.36Å
101N94.3Very high92.6Very high4 Ų459.8 Ų59.82%0.02129%0.293CS..  trans-145.318.4-178.672-17.3000113.3L76 R82 F103 Q104 A105 R195 E241L76-N101 PolarHBondContact O-ND2 2.77Å; R82-N101 HydrophobicContact CB-CB 4.23Å; N101-F103 PolarHBondContact O-N 3.24Å; N101-Q104 WeakPolarHBondContact O-CB 3.46Å; N101-Q104 PolarHBondContact O-N 2.74Å; N101-A105 PolarHBondContact O-N 2.93Å; N101-R195 PolarHBondContact OD1-NH2 2.66Å; N101-E241 PolarHBondContact N-OE2 3.2Å
102G94.4Very high93.4Very high0 Ų056.6 Ų56.60%028%0.281CS..Hα-helixtrans-60.7-44.5-176.400000113.1Q104 A105 L106 E241G102-Q104 VanDerWaalsContact C-N 3.34Å; G102-Q104 PolarHBondContact O-N 2.71Å; G102-A105 WeakPolarHBondContact O-CB 3.3Å; G102-A105 PolarHBondContact O-N 3.21Å; G102-L106 PolarHBondContact O-N 3.09Å; G102-E241 WeakPolarHBondContact CA-OE2 3.41Å; G102-E241 PolarHBondContact N-OE2 3.14Å
103F94.9Very high94.1Very high70 Ų7053.4 Ų53.431%0.30726%0.264SS..Hα-helixtrans-65.6-37.9177.4-168.1-96.1000112.3N101 A105 L106 V107 L238 W239N101-F103 PolarHBondContact O-N 3.24Å; F103-A105 VanDerWaalsContact C-N 3.33Å; F103-A105 PolarHBondContact O-N 2.99Å; F103-L106 WeakPolarHBondContact O-CB 3.31Å; F103-L106 PolarHBondContact O-N 3.1Å; F103-V107 HydrophobicContact CD1-CG2 4.12Å; F103-V107 HydrophobicContact CE1-CG2 3.79Å; F103-V107 HydrophobicContact CZ-CG2 4.35Å; F103-V107 WeakPolarHBondContact O-CG2 3.45Å; F103-V107 PolarHBondContact O-N 3.46Å; F103-L238 HydrophobicContact CB-CB 4.33Å; F103-L238 HydrophobicContact CD2-CB 4.49Å; F103-W239 HydrophobicContact CB-CE3 4.34Å; F103-W239 AromaticContact CD1-CE3 3.6Å; F103-W239 HydrophobicContact CD1-CE3 3.6Å; F103-W239 AromaticContact CD1-CZ3 3.67Å; F103-W239 HydrophobicContact CD1-CZ3 3.67Å; F103-W239 HydrophobicContact CD2-CB 4.25Å; F103-W239 AromaticContact CD2-CE3 3.79Å; F103-W239 HydrophobicContact CD2-CE3 3.79Å; F103-W239 AromaticContact CE1-CE3 3.73Å; F103-W239 HydrophobicContact CE1-CE3 3.73Å; F103-W239 AromaticContact CE1-CZ3 3.6Å; F103-W239 HydrophobicContact CE1-CZ3 3.6Å; F103-W239 AromaticContact CE2-CE3 3.9Å; F103-W239 HydrophobicContact CE2-CE3 3.9Å; F103-W239 AromaticContact CG-CE3 3.63Å; F103-W239 HydrophobicContact CG-CE3 3.63Å; F103-W239 HydrophobicContact CG-CZ3 4.19Å; F103-W239 AromaticContact CZ-CE3 3.87Å; F103-W239 HydrophobicContact CZ-CE3 3.87Å; F103-W239 HydrophobicContact CZ-CZ3 4.07Å
104Q94.8Very high94.6Very high94 Ų9448.2 Ų48.244%0.43925%0.254SS..Hα-helixtrans-63.2-41.5173.9-63.7175.8-2.900110.9N101 G102 L106 V107 L108N101-Q104 WeakPolarHBondContact O-CB 3.46Å; N101-Q104 PolarHBondContact O-N 2.74Å; G102-Q104 VanDerWaalsContact C-N 3.34Å; G102-Q104 PolarHBondContact O-N 2.71Å; Q104-L106 VanDerWaalsContact C-N 3.33Å; Q104-L106 PolarHBondContact O-N 3.46Å; Q104-V107 PolarHBondContact O-N 3.22Å; Q104-L108 WeakPolarHBondContact O-CB 3.21Å; Q104-L108 VanDerWaalsContact O-CG 3.32Å; Q104-L108 WeakPolarHBondContact O-CG 3.34Å; Q104-L108 PolarHBondContact O-N 3.41Å
105A95.8Very high95Very high1 Ų151.6 Ų51.61%0.00827%0.268CS..Hα-helixtrans-61.5-39.8175.600000112.1L76 N101 G102 F103 T109 I199L76-A105 HydrophobicContact CB-CB 4.01Å; L76-A105 HydrophobicContact CD1-CB 4.16Å; N101-A105 PolarHBondContact O-N 2.93Å; G102-A105 WeakPolarHBondContact O-CB 3.3Å; G102-A105 PolarHBondContact O-N 3.21Å; F103-A105 VanDerWaalsContact C-N 3.33Å; F103-A105 PolarHBondContact O-N 2.99Å; A105-T109 WeakPolarHBondContact O-CB 3.36Å; A105-T109 PolarHBondContact O-N 3.21Å; A105-T109 PolarHBondContact O-OG1 3.2Å; A105-I199 HydrophobicContact CB-CD1 4.05Å
106L97.1Very high95.2Very high17 Ų1747.4 Ų47.49%0.08926%0.258CS..Hα-helixtrans-60.6-50173.3175.665.6000111.6G102 F103 Q104 T109 A110 I199 V202 L231 L238G102-L106 PolarHBondContact O-N 3.09Å; F103-L106 WeakPolarHBondContact O-CB 3.31Å; F103-L106 PolarHBondContact O-N 3.1Å; Q104-L106 VanDerWaalsContact C-N 3.33Å; Q104-L106 PolarHBondContact O-N 3.46Å; L106-T109 PolarHBondContact O-N 3.37Å; L106-A110 WeakPolarHBondContact O-CB 3.4Å; L106-A110 PolarHBondContact O-N 3.03Å; L106-I199 HydrophobicContact CB-CD1 4.48Å; L106-I199 HydrophobicContact CD1-CG2 3.92Å; L106-V202 HydrophobicContact CD1-CG1 4.28Å; L106-L231 HydrophobicContact CD2-CD1 4.47Å; L106-L238 HydrophobicContact CB-CD1 3.81Å; L106-L238 HydrophobicContact CD2-CD1 4Å; L106-L238 HydrophobicContact CG-CD1 4.37Å
107V96.6Very high95.3Very high63 Ų6348.7 Ų48.738%0.38227%0.268SS..Hα-helixtrans-62.6-47.6-179.7173.30000111.3F103 Q104 T109 A110 L111F103-V107 HydrophobicContact CD1-CG2 4.12Å; F103-V107 HydrophobicContact CE1-CG2 3.79Å; F103-V107 HydrophobicContact CZ-CG2 4.35Å; F103-V107 WeakPolarHBondContact O-CG2 3.45Å; F103-V107 PolarHBondContact O-N 3.46Å; Q104-V107 PolarHBondContact O-N 3.22Å; V107-T109 VanDerWaalsContact C-N 3.32Å; V107-T109 PolarHBondContact O-N 3.09Å; V107-A110 PolarHBondContact O-N 3.22Å; V107-L111 HydrophobicContact CG1-CD1 4.07Å; V107-L111 HydrophobicContact CG1-CG 4.42Å; V107-L111 WeakPolarHBondContact O-CG 3.33Å; V107-L111 PolarHBondContact O-N 3.48Å
108L96.6Very high95.3Very high66 Ų6645.6 Ų45.635%0.34627%0.271SS..Hα-helixtrans-63.1-39.9178.2-70.2174.4000111.6L76 L79 Q104 L111 L112L76-L108 HydrophobicContact CD2-CB 4.09Å; L76-L108 HydrophobicContact CD2-CD1 3.9Å; L79-L108 HydrophobicContact CD1-CD1 3.8Å; Q104-L108 WeakPolarHBondContact O-CB 3.21Å; Q104-L108 VanDerWaalsContact O-CG 3.32Å; Q104-L108 WeakPolarHBondContact O-CG 3.34Å; Q104-L108 PolarHBondContact O-N 3.41Å; L108-L111 PolarHBondContact O-N 3.34Å; L108-L112 WeakPolarHBondContact O-CB 3.26Å; L108-L112 VanDerWaalsContact O-CG 3.25Å; L108-L112 WeakPolarHBondContact O-CG 3.36Å; L108-L112 PolarHBondContact O-N 2.96Å
109T97.1Very high95.4Very high5 Ų549.7 Ų49.73%0.03131%0.306CS..Hα-helixtrans-60.9-47.3173.7-600000110.7W69 Q73 L76 A105 L106 V107 L111 L112 V113 I199W69-T109 HydrophobicContact CH2-CG2 3.88Å; W69-T109 HydrophobicContact CZ3-CG2 3.69Å; Q73-T109 PolarHBondContact NE2-OG1 3.37Å; L76-T109 WeakPolarHBondContact CD1-OG1 3.27Å; A105-T109 WeakPolarHBondContact O-CB 3.36Å; A105-T109 PolarHBondContact O-N 3.21Å; A105-T109 PolarHBondContact O-OG1 3.2Å; L106-T109 PolarHBondContact O-N 3.37Å; V107-T109 VanDerWaalsContact C-N 3.32Å; V107-T109 PolarHBondContact O-N 3.09Å; T109-L111 VanDerWaalsContact C-N 3.34Å; T109-L111 PolarHBondContact O-N 3.44Å; T109-L112 PolarHBondContact O-N 2.94Å; T109-V113 HydrophobicContact CG2-CG2 4.39Å; T109-V113 WeakPolarHBondContact O-CG2 3.4Å; T109-V113 PolarHBondContact O-N 3.29Å; T109-I199 HydrophobicContact CG2-CG2 4.07Å
110A96.6Very high95.5Very high57 Ų5752.2 Ų52.247%0.47133%0.333SS..Hα-helixtrans-61.4-41.1178.500000112.2L106 V107 V113 G114L106-A110 WeakPolarHBondContact O-CB 3.4Å; L106-A110 PolarHBondContact O-N 3.03Å; V107-A110 PolarHBondContact O-N 3.22Å; A110-V113 PolarHBondContact O-N 3.49Å; A110-G114 PolarHBondContact O-N 2.99Å
111L96.9Very high95.5Very high101 Ų10155.3 Ų55.353%0.52935%0.349SS..Hα-helixtrans-63.6-46.1175-70.7172.6000111.8V107 L108 T109 V113 G114 L115V107-L111 HydrophobicContact CG1-CD1 4.07Å; V107-L111 HydrophobicContact CG1-CG 4.42Å; V107-L111 WeakPolarHBondContact O-CG 3.33Å; V107-L111 PolarHBondContact O-N 3.48Å; L108-L111 PolarHBondContact O-N 3.34Å; T109-L111 VanDerWaalsContact C-N 3.34Å; T109-L111 PolarHBondContact O-N 3.44Å; L111-V113 PolarHBondContact O-N 3.49Å; L111-G114 PolarHBondContact O-N 3.24Å; L111-L115 WeakPolarHBondContact O-CB 3.37Å; L111-L115 VanDerWaalsContact O-CG 3.29Å; L111-L115 WeakPolarHBondContact O-CG 3.22Å; L111-L115 PolarHBondContact O-N 3.03Å
112L96.7Very high95.5Very high87 Ų8759.3 Ų59.346%0.45538%0.376SS..Hα-helixtrans-63-41.4178.3-72.8172000111.9L72 L108 T109 G116L72-L112 HydrophobicContact CD1-CD1 3.79Å; L108-L112 WeakPolarHBondContact O-CB 3.26Å; L108-L112 VanDerWaalsContact O-CG 3.25Å; L108-L112 WeakPolarHBondContact O-CG 3.36Å; L108-L112 PolarHBondContact O-N 2.96Å; T109-L112 PolarHBondContact O-N 2.94Å; L112-G116 PolarHBondContact O-N 3.31Å
113V96Very high95.5Very high20 Ų2060 Ų6012%0.12138%0.379CS..Hα-helixtrans-67.5-42.8175.4173.80000110.8T109 A110 L111 G116 V117 L123 L203 L206T109-V113 HydrophobicContact CG2-CG2 4.39Å; T109-V113 WeakPolarHBondContact O-CG2 3.4Å; T109-V113 PolarHBondContact O-N 3.29Å; A110-V113 PolarHBondContact O-N 3.49Å; L111-V113 PolarHBondContact O-N 3.49Å; V113-G116 CarbonylContact O-C 3.3Å; V113-G116 PolarHBondContact O-N 3.08Å; V113-V117 HydrophobicContact CG1-CG2 4.38Å; V113-V117 WeakPolarHBondContact O-CG2 3.49Å; V113-V117 PolarHBondContact O-N 3.46Å; V113-L123 HydrophobicContact CG1-CD1 4.25Å; V113-L123 HydrophobicContact CG1-CD2 3.85Å; V113-L203 HydrophobicContact CG1-CD1 4.07Å; V113-L203 HydrophobicContact CG2-CD1 3.88Å; V113-L206 HydrophobicContact CG1-CD2 4.42Å
114G95.5Very high95.4Very high42 Ų4256.7 Ų56.743%0.43337%0.365SS..Hα-helixtrans-60.8-44.4176.100000112.8A110 L111 V117 S118A110-G114 PolarHBondContact O-N 2.99Å; L111-G114 PolarHBondContact O-N 3.24Å; G114-V117 PolarHBondContact O-N 3.41Å; G114-S118 PolarHBondContact O-N 2.78Å
115L96.3Very high95.4Very high114 Ų11454.4 Ų54.460%0.59736%0.362SS*.Hα-helixtrans-61.4-45.2172.4-73172.9000111.1L111 V117 S118 A119L111-L115 WeakPolarHBondContact O-CB 3.37Å; L111-L115 VanDerWaalsContact O-CG 3.29Å; L111-L115 WeakPolarHBondContact O-CG 3.22Å; L111-L115 PolarHBondContact O-N 3.03Å; L115-V117 PolarHBondContact O-N 3.23Å; L115-S118 WeakPolarHBondContact CA-OG 3.37Å; L115-S118 PolarHBondContact O-N 3.26Å; L115-S118 PolarHBondContact O-OG 2.97Å; L115-A119 WeakPolarHBondContact O-CB 3.41Å; L115-A119 PolarHBondContact O-N 3.01Å
116G95.4Very high95.4Very high20 Ų2056 Ų5621%0.20637%0.37CS..Hα-helixtrans-55.8-48.8174.700000111.9L112 V113 S118 A119 G120 L121L112-G116 PolarHBondContact O-N 3.31Å; V113-G116 CarbonylContact O-C 3.3Å; V113-G116 PolarHBondContact O-N 3.08Å; G116-S118 VanDerWaalsContact C-N 3.35Å; G116-S118 PolarHBondContact O-N 3.1Å; G116-A119 CarbonylContact O-C 3.52Å; G116-A119 WeakPolarHBondContact O-CA 3.3Å; G116-A119 PolarHBondContact O-N 3.28Å; G116-A119 VanDerWaalsContact O-N 3.07Å; G116-G120 PolarHBondContact O-N 3.41Å; G116-G120 VanDerWaalsContact O-N 3.14Å; G116-L121 WeakPolarHBondContact O-CB 3.48Å; G116-L121 PolarHBondContact O-N 3.02Å
117V94.4Very high95.4Very high64 Ų6455.5 Ų55.539%0.38837%0.368SS..Hα-helixtrans-61.5-43.1177.9171.10000110.9V113 G114 L115 A119 G120 L123V113-V117 HydrophobicContact CG1-CG2 4.38Å; V113-V117 WeakPolarHBondContact O-CG2 3.49Å; V113-V117 PolarHBondContact O-N 3.46Å; G114-V117 PolarHBondContact O-N 3.41Å; L115-V117 PolarHBondContact O-N 3.23Å; V117-A119 PolarHBondContact O-N 3.41Å; V117-G120 PolarHBondContact O-N 2.83Å; V117-L123 HydrophobicContact CG2-CB 3.84Å; V117-L123 HydrophobicContact CG2-CD2 4.07Å
118S93.7Very high95.2Very high100 Ų10056.3 Ų56.370%0.69937%0.367SS*.Hα-helixtrans-63.2-27175.375.20000113.3G114 L115 G116 G120G114-S118 PolarHBondContact O-N 2.78Å; L115-S118 WeakPolarHBondContact CA-OG 3.37Å; L115-S118 PolarHBondContact O-N 3.26Å; L115-S118 PolarHBondContact O-OG 2.97Å; G116-S118 VanDerWaalsContact C-N 3.35Å; G116-S118 PolarHBondContact O-N 3.1Å; S118-G120 VanDerWaalsContact C-N 3.35Å
119A95.7Very high95.1Very high89 Ų8955 Ų5574%0.73636%0.36SS*.THydrogen-bonded Turntrans-89.77174.600000113.6L115 G116 V117L115-A119 WeakPolarHBondContact O-CB 3.41Å; L115-A119 PolarHBondContact O-N 3.01Å; G116-A119 CarbonylContact O-C 3.52Å; G116-A119 WeakPolarHBondContact O-CA 3.3Å; G116-A119 PolarHBondContact O-N 3.28Å; G116-A119 VanDerWaalsContact O-N 3.07Å; V117-A119 PolarHBondContact O-N 3.41Å
120G92.9Very high95.1Very high60 Ų6055 Ų5562%0.61936%0.36SS*.THydrogen-bonded Turntrans95.115.7175.900000115.9G116 V117 S118 P122G116-G120 PolarHBondContact O-N 3.41Å; G116-G120 VanDerWaalsContact O-N 3.14Å; V117-G120 PolarHBondContact O-N 2.83Å; S118-G120 VanDerWaalsContact C-N 3.35Å; G120-P122 WeakPolarHBondContact O-CD 3.32Å
121L93.2Very high95Very high87 Ų8752.8 Ų52.846%0.45534%0.34SS..  trans-62.9120.6172-17774000110.2G116 L123G116-L121 WeakPolarHBondContact O-CB 3.48Å; G116-L121 PolarHBondContact O-N 3.02Å; L121-L123 VanDerWaalsContact C-N 3.26Å; L121-L123 PolarHBondContact O-N 3.2Å
122P94Very high95Very high89 Ų8948.5 Ų48.558%0.57832%0.318SS*.  trans-80.570.9-176.533.6-36.3000111.1G120 G124 A125G120-P122 WeakPolarHBondContact O-CD 3.32Å; P122-G124 PolarHBondContact O-N 3.5Å; P122-A125 HydrophobicContact CB-CB 4.26Å; P122-A125 VanDerWaalsContact O-CB 3.29Å; P122-A125 WeakPolarHBondContact O-CB 3.49Å; P122-A125 PolarHBondContact O-N 3.09Å
123L95.1Very high95.1Very high14 Ų1445 Ų457%0.07330%0.3CS..G310 helixtrans-58.2-35.7-177-174.763.3000112.4V113 V117 L121 A125 L126 L203 L206 A207 V210V113-L123 HydrophobicContact CG1-CD1 4.25Å; V113-L123 HydrophobicContact CG1-CD2 3.85Å; V117-L123 HydrophobicContact CG2-CB 3.84Å; V117-L123 HydrophobicContact CG2-CD2 4.07Å; L121-L123 VanDerWaalsContact C-N 3.26Å; L121-L123 PolarHBondContact O-N 3.2Å; L123-A125 PolarHBondContact O-N 2.85Å; L123-A125 VanDerWaalsContact O-N 3.11Å; L123-L126 WeakPolarHBondContact O-CB 3.27Å; L123-L126 PolarHBondContact O-N 2.97Å; L123-L126 VanDerWaalsContact O-N 3.09Å; L123-L203 HydrophobicContact CD1-CD1 4.02Å; L123-L206 HydrophobicContact CD2-CD2 3.95Å; L123-L206 HydrophobicContact CD2-CG 3.91Å; L123-A207 HydrophobicContact CD1-CB 3.94Å; L123-A207 HydrophobicContact CG-CB 3.92Å; L123-V210 HydrophobicContact CD2-CG2 4.26Å
124G93.7Very high95.2Very high0 Ų044 Ų440%029%0.294CS..G310 helixtrans-65-7.817500000115.2P122 P127 K211P122-G124 PolarHBondContact O-N 3.5Å; G124-P127 WeakPolarHBondContact O-CD 3.46Å; G124-K211 WeakPolarHBondContact O-CD 3.44Å; G124-K211 WeakPolarHBondContact O-CE 3.33Å
125A94.9Very high95.2Very high46 Ų4645 Ų4538%0.3829%0.287SS..G310 helixtrans-82.3-20.217200000113.1P122 L123 E128P122-A125 HydrophobicContact CB-CB 4.26Å; P122-A125 VanDerWaalsContact O-CB 3.29Å; P122-A125 WeakPolarHBondContact O-CB 3.49Å; P122-A125 PolarHBondContact O-N 3.09Å; L123-A125 PolarHBondContact O-N 2.85Å; L123-A125 VanDerWaalsContact O-N 3.11Å; A125-E128 PolarHBondContact O-N 3.29Å
126L95.8Very high95.3Very high34 Ų3439.7 Ų39.718%0.17826%0.259CS..G310 helixtrans-59.4-39.5-176.9-173.8152000113.9L123 E128 M129 L130 L133 I204 A207L123-L126 WeakPolarHBondContact O-CB 3.27Å; L123-L126 PolarHBondContact O-N 2.97Å; L123-L126 VanDerWaalsContact O-N 3.09Å; L126-E128 PolarHBondContact O-N 2.87Å; L126-E128 VanDerWaalsContact O-N 3.15Å; L126-M129 WeakPolarHBondContact O-CA 3.3Å; L126-M129 PolarHBondContact O-N 3.41Å; L126-L130 HydrophobicContact CD2-CD2 3.87Å; L126-L130 PolarHBondContact O-N 2.92Å; L126-L133 HydrophobicContact CG-CD1 4.35Å; L126-I204 HydrophobicContact CD2-CG1 4.11Å; L126-A207 HydrophobicContact CB-CB 3.93Å; L126-A207 HydrophobicContact CD2-CB 3.94Å; L126-A207 HydrophobicContact CG-CB 4.35Å
127P95.6Very high95.5Very high7 Ų738.7 Ų38.75%0.04525%0.249CC..G310 helixtrans-54.2-32.9176.4-32.640.9000114.6G124 M129 L130 A207 L208 K211 L279G124-P127 WeakPolarHBondContact O-CD 3.46Å; P127-M129 VanDerWaalsContact C-N 3.26Å; P127-M129 PolarHBondContact O-N 3.4Å; P127-L130 HydrophobicContact CB-CD1 4.49Å; P127-L130 WeakPolarHBondContact O-CG 3.33Å; P127-L130 PolarHBondContact O-N 3.39Å; P127-A207 HydrophobicContact CG-CB 4.31Å; P127-L208 HydrophobicContact CB-CD2 3.75Å; P127-L208 HydrophobicContact CG-CD2 3.79Å; P127-L208 HydrophobicContact CG-CG 4.16Å; P127-K211 HydrophobicContact CG-CB 3.91Å; P127-K211 HydrophobicContact CG-CG 4.24Å; P127-L279 HydrophobicContact CB-CD2 4.27Å
128E93.2Very high95.6Very high80 Ų8036.2 Ų36.237%0.37423%0.234SC..G310 helixtrans-72.1-24.4178.6-65.5-56.8151.800112.3R38 A125 L126 R280R38-E128 IonicContact CZ-OE2 3.36Å; R38-E128 PolarHBondContact NH1-O 3.38Å; R38-E128 IonicContact NH2-OE2 3.28Å; R38-E128 PolarHBondContact NH2-OE2 2.67Å; A125-E128 PolarHBondContact O-N 3.29Å; L126-E128 PolarHBondContact O-N 2.87Å; L126-E128 VanDerWaalsContact O-N 3.15Å; E128-R280 IonicContact OE1-NH2 2.81Å; E128-R280 PolarHBondContact OE1-NH2 3.28Å; E128-R280 IonicContact OE2-NH2 2.69Å
129M95.1Very high95.8Very high38 Ų3834.8 Ų34.819%0.18722%0.218CC..G310 helixtrans-91.92.8178.1-60.8-174.164.800113.9R61 A62 L65 L126 P127 L131 P132 L133R61-M129 HydrophobicContact CB-CE 3.76Å; A62-M129 HydrophobicContact CB-CE 3.81Å; L65-M129 HydrophobicContact CD1-CE 3.69Å; L65-M129 HydrophobicContact CD1-SD 3.84Å; L126-M129 WeakPolarHBondContact O-CA 3.3Å; L126-M129 PolarHBondContact O-N 3.41Å; P127-M129 VanDerWaalsContact C-N 3.26Å; P127-M129 PolarHBondContact O-N 3.4Å; M129-L131 VanDerWaalsContact C-N 3.29Å; M129-L131 PolarHBondContact O-N 2.99Å; M129-P132 HydrophobicContact CB-CG 4.38Å; M129-P132 WeakPolarHBondContact O-CD 3.25Å; M129-P132 VanDerWaalsContact O-CG 3.27Å; M129-P132 WeakPolarHBondContact O-CG 3.5Å; M129-L133 HydrophobicContact CB-CD1 4.04Å; M129-L133 HydrophobicContact CB-CG 4.33Å; M129-L133 VanDerWaalsContact O-CB 3.29Å; M129-L133 WeakPolarHBondContact O-CB 3.44Å; M129-L133 WeakPolarHBondContact O-CD1 3.14Å; M129-L133 WeakPolarHBondContact O-CG 3.5Å; M129-L133 PolarHBondContact O-N 2.89Å
130L95.9Very high95.9Very high7 Ų732 Ų324%0.03719%0.192CC..Hα-helixtrans-59.2-39.3-177.4-72175.1000113.2L126 P127 L133 A134 I204 L208 F269 Q276L126-L130 HydrophobicContact CD2-CD2 3.87Å; L126-L130 PolarHBondContact O-N 2.92Å; P127-L130 HydrophobicContact CB-CD1 4.49Å; P127-L130 WeakPolarHBondContact O-CG 3.33Å; P127-L130 PolarHBondContact O-N 3.39Å; L130-L133 PolarHBondContact O-N 3.42Å; L130-A134 VanDerWaalsContact O-CB 3.26Å; L130-A134 WeakPolarHBondContact O-CB 3.36Å; L130-A134 PolarHBondContact O-N 2.86Å; L130-I204 HydrophobicContact CD1-CG2 4.34Å; L130-I204 HydrophobicContact CD2-CB 4.48Å; L130-I204 HydrophobicContact CD2-CD1 3.99Å; L130-I204 HydrophobicContact CD2-CG1 3.92Å; L130-I204 HydrophobicContact CD2-CG2 3.78Å; L130-L208 HydrophobicContact CD1-CD2 4.37Å; L130-F269 HydrophobicContact CD2-CD1 4.21Å; L130-F269 HydrophobicContact CD2-CE1 4.04Å; L130-Q276 HydrophobicContact CD1-CG 4.09Å
131L95.6Very high96.2Very high9 Ų929.2 Ų29.25%0.04716%0.163CC..Hα-helixtrans-64.4-52.7179.4-175.566.8000112.2F31 L34 L35 P52 A56 L57 M129 L133 A134 F135F31-L131 HydrophobicContact CD1-CD1 3.66Å; F31-L131 HydrophobicContact CE1-CD1 4.11Å; L34-L131 HydrophobicContact CD1-CD1 4.48Å; L35-L131 HydrophobicContact CD2-CD1 4.4Å; L35-L131 HydrophobicContact CD2-CD2 4.12Å; P52-L131 HydrophobicContact CB-CD2 3.98Å; P52-L131 HydrophobicContact CG-CD2 4.14Å; A56-L131 HydrophobicContact CB-CD2 4.42Å; L57-L131 HydrophobicContact CD2-CD1 3.95Å; L57-L131 HydrophobicContact CD2-CD2 3.99Å; L57-L131 HydrophobicContact CD2-CG 3.82Å; M129-L131 VanDerWaalsContact C-N 3.29Å; M129-L131 PolarHBondContact O-N 2.99Å; L131-L133 VanDerWaalsContact C-N 3.34Å; L131-L133 PolarHBondContact O-N 2.76Å; L131-A134 PolarHBondContact O-N 3.47Å; L131-F135 PolarHBondContact O-N 2.93Å
132P96.9Very high96.4Very high12 Ų1228.2 Ų28.28%0.07816%0.155CC..Hα-helixtrans-68-29.8175.724.4-33.4000113.8L57 A62 M129 F135 V136L57-P132 WeakPolarHBondContact O-CA 3.44Å; L57-P132 WeakPolarHBondContact O-CB 3.3Å; A62-P132 HydrophobicContact CB-CB 3.89Å; A62-P132 HydrophobicContact CB-CG 4.28Å; M129-P132 HydrophobicContact CB-CG 4.38Å; M129-P132 WeakPolarHBondContact O-CD 3.25Å; M129-P132 VanDerWaalsContact O-CG 3.27Å; M129-P132 WeakPolarHBondContact O-CG 3.5Å; P132-F135 PolarHBondContact O-N 3.48Å; P132-V136 WeakPolarHBondContact O-CG2 3.13Å; P132-V136 PolarHBondContact O-N 2.94Å
133L97.8Very high96.6Very high13 Ų1328.9 Ų28.97%0.06815%0.153CC..Hα-helixtrans-65-43.7172.2-74.9168.2000111.7A62 L65 W66 L126 M129 L130 L131 F135 V136 A137 F269A62-L133 HydrophobicContact CB-CD2 3.98Å; A62-L133 HydrophobicContact CB-CG 4.15Å; A62-L133 WeakPolarHBondContact O-CD2 3.27Å; L65-L133 HydrophobicContact CB-CD2 4.3Å; W66-L133 HydrophobicContact CB-CD2 4.34Å; L126-L133 HydrophobicContact CG-CD1 4.35Å; M129-L133 HydrophobicContact CB-CD1 4.04Å; M129-L133 HydrophobicContact CB-CG 4.33Å; M129-L133 VanDerWaalsContact O-CB 3.29Å; M129-L133 WeakPolarHBondContact O-CB 3.44Å; M129-L133 WeakPolarHBondContact O-CD1 3.14Å; M129-L133 WeakPolarHBondContact O-CG 3.5Å; M129-L133 PolarHBondContact O-N 2.89Å; L130-L133 PolarHBondContact O-N 3.42Å; L131-L133 VanDerWaalsContact C-N 3.34Å; L131-L133 PolarHBondContact O-N 2.76Å; L133-F135 VanDerWaalsContact C-N 3.28Å; L133-F135 PolarHBondContact O-N 3.07Å; L133-V136 PolarHBondContact O-N 2.63Å; L133-A137 WeakPolarHBondContact O-CB 3.26Å; L133-A137 PolarHBondContact O-N 3.12Å; L133-F269 HydrophobicContact CB-CE1 3.96Å; L133-F269 HydrophobicContact CB-CZ 3.87Å
134A97.7Very high96.7Very high0 Ų030 Ų300%016%0.157CC..Hα-helixtrans-63-36175.800000112M30 F31 L34 L130 L131 T138 F269M30-A134 HydrophobicContact CE-CB 3.94Å; F31-A134 HydrophobicContact CE1-CB 4Å; F31-A134 HydrophobicContact CZ-CB 4.47Å; L34-A134 HydrophobicContact CD1-CB 3.46Å; L34-A134 VanDerWaalsContact CD1-CB 3.46Å; L130-A134 VanDerWaalsContact O-CB 3.26Å; L130-A134 WeakPolarHBondContact O-CB 3.36Å; L130-A134 PolarHBondContact O-N 2.86Å; L131-A134 PolarHBondContact O-N 3.47Å; A134-T138 WeakPolarHBondContact O-CB 3.38Å; A134-T138 PolarHBondContact O-N 3Å; A134-T138 PolarHBondContact O-OG1 3.22Å; A134-F269 HydrophobicContact CB-CB 4.48Å; A134-F269 HydrophobicContact CB-CD1 3.88Å; A134-F269 HydrophobicContact CB-CD2 3.81Å; A134-F269 HydrophobicContact CB-CE1 4.06Å; A134-F269 HydrophobicContact CB-CE2 4.07Å; A134-F269 HydrophobicContact CB-CG 3.79Å; A134-F269 HydrophobicContact CB-CZ 4.18Å
135F97.3Very high96.9Very high62 Ų6230.1 Ų30.127%0.27216%0.157SC..Hα-helixtrans-63.3-49.7172.2-173.5-98.7000112.6F31 L57 W58 L131 P132 L133 A137 T138 L139F31-F135 HydrophobicContact CE1-CB 4.22Å; F31-F135 HydrophobicContact CZ-CB 4.15Å; F31-F135 HydrophobicContact CZ-CD2 4.22Å; L57-F135 HydrophobicContact CB-CB 4.46Å; L57-F135 HydrophobicContact CB-CD2 4.13Å; L57-F135 HydrophobicContact CB-CG 4.11Å; L57-F135 HydrophobicContact CD1-CD2 4.4Å; L57-F135 HydrophobicContact CD1-CE2 4.48Å; L57-F135 VanDerWaalsContact O-CB 3.26Å; L57-F135 WeakPolarHBondContact O-CB 3.35Å; L57-F135 WeakPolarHBondContact O-CD1 3.33Å; L57-F135 WeakPolarHBondContact O-CG 3.34Å; W58-F135 AromaticContact CE3-CD1 3.98Å; W58-F135 HydrophobicContact CE3-CD1 3.98Å; W58-F135 AromaticContact CE3-CE1 3.85Å; W58-F135 HydrophobicContact CE3-CE1 3.85Å; W58-F135 HydrophobicContact CZ3-CE1 4.37Å; L131-F135 PolarHBondContact O-N 2.93Å; P132-F135 PolarHBondContact O-N 3.48Å; L133-F135 VanDerWaalsContact C-N 3.28Å; L133-F135 PolarHBondContact O-N 3.07Å; F135-A137 VanDerWaalsContact C-N 3.33Å; F135-A137 PolarHBondContact O-N 3.07Å; F135-T138 WeakPolarHBondContact O-CB 3.29Å; F135-T138 PolarHBondContact O-N 3.36Å; F135-L139 PolarHBondContact O-N 3.04Å
136V97.9Very high97Very high2 Ų232.5 Ų32.51%0.01216%0.163CC..Hα-helixtrans-62.2-40.9176.3174.10000111.5W58 A62 L63 W66 P132 L133 L139 T140W58-V136 HydrophobicContact CE3-CG2 4.44Å; W58-V136 HydrophobicContact CZ3-CG2 4.14Å; A62-V136 HydrophobicContact CB-CG2 4.47Å; L63-V136 HydrophobicContact CB-CG2 4.32Å; L63-V136 HydrophobicContact CD1-CG1 3.73Å; W66-V136 HydrophobicContact CB-CG1 3.79Å; W66-V136 VanDerWaalsContact CD1-CG1 3.41Å; W66-V136 HydrophobicContact CG-CG1 3.64Å; P132-V136 WeakPolarHBondContact O-CG2 3.13Å; P132-V136 PolarHBondContact O-N 2.94Å; L133-V136 PolarHBondContact O-N 2.63Å; V136-L139 PolarHBondContact O-N 3.11Å; V136-T140 WeakPolarHBondContact O-CB 3.4Å; V136-T140 PolarHBondContact O-N 3.25Å; V136-T140 PolarHBondContact O-OG1 2.96Å
137A98.1Very high97.1Very high0 Ų035.2 Ų35.20%017%0.174CC..Hα-helixtrans-64.2-41.117700000111.9W66 L133 F135 T140 A141 A265 F269W66-A137 HydrophobicContact CD2-CB 4.43Å; W66-A137 HydrophobicContact CE3-CB 4.31Å; W66-A137 HydrophobicContact CH2-CB 3.65Å; W66-A137 HydrophobicContact CZ2-CB 3.76Å; W66-A137 HydrophobicContact CZ3-CB 3.93Å; L133-A137 WeakPolarHBondContact O-CB 3.26Å; L133-A137 PolarHBondContact O-N 3.12Å; F135-A137 VanDerWaalsContact C-N 3.33Å; F135-A137 PolarHBondContact O-N 3.07Å; A137-T140 WeakPolarHBondContact O-CB 3.49Å; A137-T140 PolarHBondContact O-N 2.89Å; A137-A141 PolarHBondContact O-N 2.82Å; A137-A265 HydrophobicContact CB-CB 4.05Å; A137-F269 HydrophobicContact CB-CE2 3.68Å; A137-F269 HydrophobicContact CB-CZ 4.41Å
138T98.1Very high97.1Very high11 Ų1135.2 Ų35.27%0.06717%0.173CC..Hα-helixtrans-61.6-48.5174.1-58.40000111.3P27 M30 F31 A134 F135 T140 A141 F142 F261P27-T138 HydrophobicContact CB-CG2 4.07Å; P27-T138 HydrophobicContact CG-CG2 4.18Å; M30-T138 VanDerWaalsContact CE-OG1 3.23Å; M30-T138 WeakPolarHBondContact CE-OG1 3.42Å; F31-T138 HydrophobicContact CE2-CG2 4.49Å; A134-T138 WeakPolarHBondContact O-CB 3.38Å; A134-T138 PolarHBondContact O-N 3Å; A134-T138 PolarHBondContact O-OG1 3.22Å; F135-T138 WeakPolarHBondContact O-CB 3.29Å; F135-T138 PolarHBondContact O-N 3.36Å; T138-T140 VanDerWaalsContact C-N 3.29Å; T138-T140 PolarHBondContact O-N 3.4Å; T138-A141 WeakPolarHBondContact O-CB 3.41Å; T138-A141 PolarHBondContact O-N 3.45Å; T138-A141 VanDerWaalsContact O-N 3.14Å; T138-F142 HydrophobicContact CG2-CD2 3.97Å; T138-F142 HydrophobicContact CG2-CE2 3.81Å; T138-F142 WeakPolarHBondContact O-CD2 3.34Å; T138-F142 PolarHBondContact O-N 2.72Å; T138-F261 HydrophobicContact CG2-CD2 4.37Å; T138-F261 HydrophobicContact CG2-CE2 3.95Å
139L97.6Very high97.3Very high71 Ų7133.6 Ų33.637%0.37216%0.164SC..Hα-helixtrans-60.8-41.8177-17961.6000111.2W58 F135 V136 A141 F142 I143W58-L139 HydrophobicContact CZ3-CD2 4.37Å; F135-L139 PolarHBondContact O-N 3.04Å; V136-L139 PolarHBondContact O-N 3.11Å; L139-A141 VanDerWaalsContact C-N 3.33Å; L139-A141 PolarHBondContact O-N 3.27Å; L139-F142 PolarHBondContact O-N 2.83Å; L139-I143 HydrophobicContact CD1-CD1 3.95Å; L139-I143 HydrophobicContact CD1-CG1 4.23Å; L139-I143 HydrophobicContact CD2-CD1 4.39Å; L139-I143 HydrophobicContact CG-CD1 3.77Å; L139-I143 HydrophobicContact CG-CG1 4.42Å; L139-I143 WeakPolarHBondContact O-CG1 3.46Å; L139-I143 PolarHBondContact O-N 2.84Å
140T97.8Very high97.3Very high31 Ų3137.4 Ų37.419%0.1918%0.183CC..Hα-helixtrans-59.1-44.6174.4-57.60000110.8W66 L70 V136 A137 T138 F142 I143 F144 I264W66-T140 HydrophobicContact CZ2-CG2 4.47Å; W66-T140 PolarHBondContact NE1-OG1 2.87Å; L70-T140 HydrophobicContact CD1-CG2 4.19Å; V136-T140 WeakPolarHBondContact O-CB 3.4Å; V136-T140 PolarHBondContact O-N 3.25Å; V136-T140 PolarHBondContact O-OG1 2.96Å; A137-T140 WeakPolarHBondContact O-CB 3.49Å; A137-T140 PolarHBondContact O-N 2.89Å; T138-T140 VanDerWaalsContact C-N 3.29Å; T138-T140 PolarHBondContact O-N 3.4Å; T140-F142 PolarHBondContact O-N 2.91Å; T140-I143 PolarHBondContact O-N 2.69Å; T140-F144 WeakPolarHBondContact O-CB 3.26Å; T140-F144 PolarHBondContact O-N 2.98Å; T140-I264 HydrophobicContact CG2-CD1 4.05Å
141A98.2Very high97.2Very high0 Ų039.3 Ų39.30%019%0.191CC..Hα-helixtrans-61.1-43.3178.300000111.6A137 T138 L139 S145 F257 F261 I264A137-A141 PolarHBondContact O-N 2.82Å; T138-A141 WeakPolarHBondContact O-CB 3.41Å; T138-A141 PolarHBondContact O-N 3.45Å; T138-A141 VanDerWaalsContact O-N 3.14Å; L139-A141 VanDerWaalsContact C-N 3.33Å; L139-A141 PolarHBondContact O-N 3.27Å; A141-S145 WeakPolarHBondContact O-CB 3.45Å; A141-S145 PolarHBondContact O-N 3.37Å; A141-S145 PolarHBondContact O-OG 3.49Å; A141-F257 HydrophobicContact CB-CE2 4.29Å; A141-F261 HydrophobicContact CB-CB 3.92Å; A141-F261 HydrophobicContact CB-CD2 4.1Å; A141-I264 HydrophobicContact CB-CD1 3.81Å; A141-I264 HydrophobicContact CB-CG1 4.23Å
142F98.2Very high97.2Very high66 Ų6639 Ų3929%0.28919%0.19SC..Hα-helixtrans-62.8-51.8175.4-83.9-70.2000112.6L23 P27 T138 L139 T140 F144 S145 L146 F173 F257L23-F142 HydrophobicContact CD2-CE1 4.44Å; P27-F142 HydrophobicContact CG-CE2 4.32Å; P27-F142 HydrophobicContact CG-CZ 4.49Å; T138-F142 HydrophobicContact CG2-CD2 3.97Å; T138-F142 HydrophobicContact CG2-CE2 3.81Å; T138-F142 WeakPolarHBondContact O-CD2 3.34Å; T138-F142 PolarHBondContact O-N 2.72Å; L139-F142 PolarHBondContact O-N 2.83Å; T140-F142 PolarHBondContact O-N 2.91Å; F142-F144 VanDerWaalsContact C-N 3.31Å; F142-F144 PolarHBondContact O-N 3.15Å; F142-S145 PolarHBondContact O-N 3.01Å; F142-L146 WeakPolarHBondContact O-CB 3.26Å; F142-L146 PolarHBondContact O-N 2.97Å; F142-F173 HydrophobicContact CD1-CE1 4.43Å; F142-F173 HydrophobicContact CD1-CZ 4.26Å; F142-F257 AromaticContact CD1-CD2 3.79Å; F142-F257 HydrophobicContact CD1-CD2 3.79Å; F142-F257 AromaticContact CD1-CE2 3.54Å; F142-F257 HydrophobicContact CD1-CE2 3.54Å; F142-F257 HydrophobicContact CD1-CZ 4.44Å; F142-F257 AromaticContact CD2-CE2 3.71Å; F142-F257 HydrophobicContact CD2-CE2 3.71Å; F142-F257 HydrophobicContact CD2-CZ 4.38Å; F142-F257 AromaticContact CE1-CD2 3.87Å; F142-F257 HydrophobicContact CE1-CD2 3.87Å; F142-F257 AromaticContact CE1-CE2 3.41Å; F142-F257 HydrophobicContact CE1-CE2 3.41Å; F142-F257 VanDerWaalsContact CE1-CE2 3.41Å; F142-F257 AromaticContact CE1-CZ 3.88Å; F142-F257 HydrophobicContact CE1-CZ 3.88Å; F142-F257 AromaticContact CE2-CE2 3.58Å; F142-F257 HydrophobicContact CE2-CE2 3.58Å; F142-F257 AromaticContact CE2-CZ 3.81Å; F142-F257 HydrophobicContact CE2-CZ 3.81Å; F142-F257 HydrophobicContact CG-CD2 4.19Å; F142-F257 AromaticContact CG-CE2 3.68Å; F142-F257 HydrophobicContact CG-CE2 3.68Å; F142-F257 HydrophobicContact CZ-CD2 4.33Å; F142-F257 AromaticContact CZ-CE2 3.42Å; F142-F257 HydrophobicContact CZ-CE2 3.42Å; F142-F257 VanDerWaalsContact CZ-CE2 3.42Å; F142-F257 AromaticContact CZ-CZ 3.52Å; F142-F257 HydrophobicContact CZ-CZ 3.52Å
143I98Very high96.9Very high104 Ų10443.1 Ų43.153%0.53321%0.208SC..Hα-helixtrans-60.8-44.8-179.6-68.2170.7000110.3L139 T140 L146 F147L139-I143 HydrophobicContact CD1-CD1 3.95Å; L139-I143 HydrophobicContact CD1-CG1 4.23Å; L139-I143 HydrophobicContact CD2-CD1 4.39Å; L139-I143 HydrophobicContact CG-CD1 3.77Å; L139-I143 HydrophobicContact CG-CG1 4.42Å; L139-I143 WeakPolarHBondContact O-CG1 3.46Å; L139-I143 PolarHBondContact O-N 2.84Å; T140-I143 PolarHBondContact O-N 2.69Å; I143-L146 WeakPolarHBondContact O-CB 3.24Å; I143-L146 PolarHBondContact O-N 3.11Å; I143-F147 PolarHBondContact O-N 2.97Å
144F97.1Very high96.6Very high38 Ų3848.7 Ų48.717%0.16724%0.242CC..Hα-helixtrans-67.6-41.2-178.5-173.6-138.2000111.9T140 F142 L146 F147 L148 F188 F255 A260T140-F144 WeakPolarHBondContact O-CB 3.26Å; T140-F144 PolarHBondContact O-N 2.98Å; F142-F144 VanDerWaalsContact C-N 3.31Å; F142-F144 PolarHBondContact O-N 3.15Å; F144-L146 VanDerWaalsContact C-N 3.31Å; F144-L146 PolarHBondContact O-N 3Å; F144-F147 HydrophobicContact CD2-CD1 4.04Å; F144-F147 HydrophobicContact CE2-CD1 4.07Å; F144-F147 HydrophobicContact CE2-CE1 4.46Å; F144-F147 WeakPolarHBondContact O-CB 3.37Å; F144-F147 PolarHBondContact O-N 3.42Å; F144-L148 HydrophobicContact CD1-CD1 4.16Å; F144-L148 HydrophobicContact CD2-CG 4.41Å; F144-L148 HydrophobicContact CE1-CD1 4.09Å; F144-L148 HydrophobicContact CE2-CD1 4.45Å; F144-L148 HydrophobicContact CE2-CD2 4.27Å; F144-L148 HydrophobicContact CE2-CG 4.28Å; F144-L148 HydrophobicContact CG-CD1 4.42Å; F144-L148 HydrophobicContact CZ-CD1 4.23Å; F144-L148 HydrophobicContact CZ-CD2 4.37Å; F144-L148 HydrophobicContact CZ-CG 4.48Å; F144-L148 VanDerWaalsContact O-CG 3.28Å; F144-L148 WeakPolarHBondContact O-CG 3.11Å; F144-L148 PolarHBondContact O-N 3.3Å; F144-F188 HydrophobicContact CE1-CB 4.42Å; F144-F188 AromaticContact CE2-CD1 3.95Å; F144-F188 HydrophobicContact CE2-CD1 3.95Å; F144-F188 HydrophobicContact CE2-CE1 4.14Å; F144-F188 HydrophobicContact CE2-CG 4.17Å; F144-F188 HydrophobicContact CZ-CB 3.73Å; F144-F188 AromaticContact CZ-CD1 3.49Å; F144-F188 HydrophobicContact CZ-CD1 3.49Å; F144-F188 VanDerWaalsContact CZ-CD1 3.49Å; F144-F188 HydrophobicContact CZ-CD2 4.36Å; F144-F188 HydrophobicContact CZ-CE1 4.14Å; F144-F188 AromaticContact CZ-CG 3.62Å; F144-F188 HydrophobicContact CZ-CG 3.62Å; F144-F255 HydrophobicContact CD1-CE1 4.43Å; F144-F255 AromaticContact CE1-CE1 3.6Å; F144-F255 HydrophobicContact CE1-CE1 3.6Å; F144-F255 HydrophobicContact CE1-CZ 4.12Å; F144-F255 HydrophobicContact CZ-CE1 4.15Å; F144-A260 HydrophobicContact CD1-CB 4.37Å
145S97.8Very high96.2Very high1 Ų149.5 Ų49.51%0.00725%0.249CC..Hα-helixtrans-65-35.4175.2-55.90000112.3A141 F142 L148 Y149 F257A141-S145 WeakPolarHBondContact O-CB 3.45Å; A141-S145 PolarHBondContact O-N 3.37Å; A141-S145 PolarHBondContact O-OG 3.49Å; F142-S145 PolarHBondContact O-N 3.01Å; S145-L148 PolarHBondContact O-N 3.48Å; S145-Y149 WeakPolarHBondContact O-CB 3.5Å; S145-Y149 PolarHBondContact O-N 3.23Å; S145-F257 WeakPolarHBondContact OG-CA 3.5Å; S145-F257 PolarHBondContact OG-N 3.24Å
146L97.6Very high95.9Very high96 Ų9650.4 Ų50.450%0.50326%0.261SS..Hα-helixtrans-63.9-45.5172.5179.462.6000110.8F142 I143 F144 L148 Y149 M150 F173F142-L146 WeakPolarHBondContact O-CB 3.26Å; F142-L146 PolarHBondContact O-N 2.97Å; I143-L146 WeakPolarHBondContact O-CB 3.24Å; I143-L146 PolarHBondContact O-N 3.11Å; F144-L146 VanDerWaalsContact C-N 3.31Å; F144-L146 PolarHBondContact O-N 3Å; L146-L148 VanDerWaalsContact C-N 3.34Å; L146-L148 PolarHBondContact O-N 3.4Å; L146-Y149 PolarHBondContact O-N 3.01Å; L146-M150 HydrophobicContact CD1-CG 4.32Å; L146-M150 VanDerWaalsContact O-CG 3.29Å; L146-M150 WeakPolarHBondContact O-CG 3.43Å; L146-M150 PolarHBondContact O-N 3.21Å; L146-F173 HydrophobicContact CB-CE2 4.21Å
147F97.3Very high95.3Very high92 Ų9256.4 Ų56.440%0.40430%0.297SS..Hα-helixtrans-56.8-47.2173.8165.7-99.2000111.8I143 F144 Y149 M150 K151 I183 F188I143-F147 PolarHBondContact O-N 2.97Å; F144-F147 HydrophobicContact CD2-CD1 4.04Å; F144-F147 HydrophobicContact CE2-CD1 4.07Å; F144-F147 HydrophobicContact CE2-CE1 4.46Å; F144-F147 WeakPolarHBondContact O-CB 3.37Å; F144-F147 PolarHBondContact O-N 3.42Å; F147-Y149 PolarHBondContact O-N 3.26Å; F147-M150 PolarHBondContact O-N 3.25Å; F147-K151 HydrophobicContact CE1-CD 4.47Å; F147-K151 HydrophobicContact CZ-CD 4.42Å; F147-K151 WeakPolarHBondContact O-CB 3.41Å; F147-K151 PolarHBondContact O-N 3.41Å; F147-I183 HydrophobicContact CZ-CD1 4.22Å; F147-F188 HydrophobicContact CE1-CE2 4.1Å; F147-F188 HydrophobicContact CE1-CZ 4.32Å
148L96.6Very high94.8Very high6 Ų659.2 Ų59.23%0.03132%0.317CS..Hα-helixtrans-62.6-42.3178.3-66.7169.2000112F144 S145 L146 M150 K151 A152 P181 F188 F255F144-L148 HydrophobicContact CD1-CD1 4.16Å; F144-L148 HydrophobicContact CD2-CG 4.41Å; F144-L148 HydrophobicContact CE1-CD1 4.09Å; F144-L148 HydrophobicContact CE2-CD1 4.45Å; F144-L148 HydrophobicContact CE2-CD2 4.27Å; F144-L148 HydrophobicContact CE2-CG 4.28Å; F144-L148 HydrophobicContact CG-CD1 4.42Å; F144-L148 HydrophobicContact CZ-CD1 4.23Å; F144-L148 HydrophobicContact CZ-CD2 4.37Å; F144-L148 HydrophobicContact CZ-CG 4.48Å; F144-L148 VanDerWaalsContact O-CG 3.28Å; F144-L148 WeakPolarHBondContact O-CG 3.11Å; F144-L148 PolarHBondContact O-N 3.3Å; S145-L148 PolarHBondContact O-N 3.48Å; L146-L148 VanDerWaalsContact C-N 3.34Å; L146-L148 PolarHBondContact O-N 3.4Å; L148-M150 PolarHBondContact O-N 2.98Å; L148-K151 PolarHBondContact O-N 3.07Å; L148-A152 WeakPolarHBondContact O-CB 3.17Å; L148-A152 PolarHBondContact O-N 2.98Å; L148-P181 HydrophobicContact CD2-CB 3.72Å; L148-P181 HydrophobicContact CD2-CG 3.76Å; L148-F188 HydrophobicContact CD2-CD2 4.02Å; L148-F255 HydrophobicContact CD1-CD1 3.34Å; L148-F255 HydrophobicContact CD1-CE1 3.57Å; L148-F255 HydrophobicContact CD1-CG 4.27Å; L148-F255 HydrophobicContact CD2-CD1 4.31Å; L148-F255 HydrophobicContact CG-CD1 4.46Å
149Y96.3Very high94.3Very high47 Ų4760 Ų6018%0.18432%0.324CS..Hα-helixtrans-63.1-40.8176.9-175.5-92.2000112.4S145 L146 F147 Q153 D172 F173 R177S145-Y149 WeakPolarHBondContact O-CB 3.5Å; S145-Y149 PolarHBondContact O-N 3.23Å; L146-Y149 PolarHBondContact O-N 3.01Å; F147-Y149 PolarHBondContact O-N 3.26Å; Y149-Q153 PolarHBondContact O-NE2 3.37Å; Y149-Q153 VanDerWaalsContact O-NE2 3.09Å; Y149-D172 HydrophobicContact CE2-CB 3.94Å; Y149-F173 HydrophobicContact CD2-CB 4Å; Y149-F173 HydrophobicContact CE2-CB 4.3Å; Y149-F173 HydrophobicContact CG-CD2 4.31Å; Y149-R177 HydrophobicContact CD2-CG 4.13Å; Y149-R177 HydrophobicContact CE2-CG 4.14Å
150M95.6Very high94Very high117 Ų11757.8 Ų57.858%0.57631%0.313SS*.Hα-helixtrans-69.8-42.6175.7-67.9-57-65.800111.8L146 F147 L148 A152 Q153L146-M150 HydrophobicContact CD1-CG 4.32Å; L146-M150 VanDerWaalsContact O-CG 3.29Å; L146-M150 WeakPolarHBondContact O-CG 3.43Å; L146-M150 PolarHBondContact O-N 3.21Å; F147-M150 PolarHBondContact O-N 3.25Å; L148-M150 PolarHBondContact O-N 2.98Å; M150-A152 VanDerWaalsContact C-N 3.27Å; M150-A152 PolarHBondContact O-N 2.82Å; M150-Q153 WeakPolarHBondContact O-CB 3.43Å; M150-Q153 WeakPolarHBondContact O-CG 3.46Å; M150-Q153 PolarHBondContact O-N 3.37Å; M150-Q153 VanDerWaalsContact O-N 3.17Å
151K94.9Very high93.7Very high48 Ų4856.3 Ų56.321%0.20930%0.304CS..Hα-helixtrans-59.4-39.4175.6-175.9-165.1169.3-59.30111.4F147 L148 Q153 V154 E178 R182F147-K151 HydrophobicContact CE1-CD 4.47Å; F147-K151 HydrophobicContact CZ-CD 4.42Å; F147-K151 WeakPolarHBondContact O-CB 3.41Å; F147-K151 PolarHBondContact O-N 3.41Å; L148-K151 PolarHBondContact O-N 3.07Å; K151-Q153 PolarHBondContact O-N 2.87Å; K151-Q153 VanDerWaalsContact O-N 3.14Å; K151-V154 WeakPolarHBondContact O-CG2 3.42Å; K151-V154 PolarHBondContact O-N 2.87Å; K151-E178 IonicContact NZ-OE1 3.92Å; K151-E178 PolarHBondContact NZ-OE1 3.41Å; K151-E178 IonicContact NZ-OE2 2.96Å; K151-E178 PolarHBondContact NZ-OE2 3.31Å; K151-R182 VanDerWaalsContact CE-O 3.25Å; K151-R182 WeakPolarHBondContact CE-O 3.45Å
152A94Very high93.1Very high3 Ų359.2 Ų59.23%0.02532%0.323CS..G310 helixtrans-66.8-12.6-179.200000114.1L148 M150 V154 A155 R177 E178L148-A152 WeakPolarHBondContact O-CB 3.17Å; L148-A152 PolarHBondContact O-N 2.98Å; M150-A152 VanDerWaalsContact C-N 3.27Å; M150-A152 PolarHBondContact O-N 2.82Å; A152-V154 PolarHBondContact O-N 2.83Å; A152-A155 PolarHBondContact O-N 3.29Å; A152-R177 HydrophobicContact CB-CB 3.5Å; A152-R177 HydrophobicContact CB-CG 4.37Å; A152-E178 HydrophobicContact CB-CB 4.23Å
153Q91Very high92.4Very high98 Ų9857.3 Ų57.346%0.45832%0.322SS..G310 helixtrans-68.5-25175.6-55.8-55-37.300112.7Y149 M150 K151Y149-Q153 PolarHBondContact O-NE2 3.37Å; Y149-Q153 VanDerWaalsContact O-NE2 3.09Å; M150-Q153 WeakPolarHBondContact O-CB 3.43Å; M150-Q153 WeakPolarHBondContact O-CG 3.46Å; M150-Q153 PolarHBondContact O-N 3.37Å; M150-Q153 VanDerWaalsContact O-N 3.17Å; K151-Q153 PolarHBondContact O-N 2.87Å; K151-Q153 VanDerWaalsContact O-N 3.14Å
154V92.1Very high91.8Very high129 Ų12952.4 Ų52.478%0.78230%0.296SS*.G310 helixtrans-106.24.8177.6-60.60000112.7K151 A152K151-V154 WeakPolarHBondContact O-CG2 3.42Å; K151-V154 PolarHBondContact O-N 2.87Å; A152-V154 PolarHBondContact O-N 2.83Å
155A89.9Confident91.5Very high18 Ų1854.8 Ų54.815%0.14931%0.31CS..SBendtrans-74.6144.3178.600000111A152 L160A152-A155 PolarHBondContact O-N 3.29Å; A155-L160 HydrophobicContact CB-CD2 4.27Å
156P89.4Confident91.1Very high81 Ų8155.9 Ų55.953%0.52632%0.318SS..  trans-65.5150.6173.928.8-33.9000110.4S158 A159P156-S158 PolarHBondContact O-N 3.25Å; P156-A159 HydrophobicContact CG-CB 3.87Å; P156-A159 WeakPolarHBondContact O-CB 3.49Å; P156-A159 PolarHBondContact O-N 3.31Å
157V86.8Confident90.7Very high127 Ų12754.5 Ų54.577%0.7733%0.327SS*.G310 helixtrans-57.7-34.5-178-179.20000112A159 L160V157-A159 PolarHBondContact O-N 3.38Å; V157-L160 WeakPolarHBondContact O-CB 3.34Å; V157-L160 PolarHBondContact O-N 2.89Å; V157-L160 VanDerWaalsContact O-N 3.14Å
158S86.8Confident90.5Very high59 Ų5952.6 Ų52.641%0.41332%0.321SS..G310 helixtrans-65.9-16.617757.50000114.6P156P156-S158 PolarHBondContact O-N 3.25Å
159A88.1Confident90.4Very high27 Ų2756 Ų5622%0.22334%0.343CS..G310 helixtrans-95.6-2.9177.100000112.8P156 V157 L179P156-A159 HydrophobicContact CG-CB 3.87Å; P156-A159 WeakPolarHBondContact O-CB 3.49Å; P156-A159 PolarHBondContact O-N 3.31Å; V157-A159 PolarHBondContact O-N 3.38Å; A159-L179 PolarHBondContact O-N 2.77Å
160L91.4Very high90.4Very high26 Ų2657.8 Ų57.814%0.13636%0.355CS..BIsolated β-bridgetrans-81.1141.9-179.1-59.2-179.6000111.1A155 V157 I165 R177A155-L160 HydrophobicContact CB-CD2 4.27Å; V157-L160 WeakPolarHBondContact O-CB 3.34Å; V157-L160 PolarHBondContact O-N 2.89Å; V157-L160 VanDerWaalsContact O-N 3.14Å; L160-I165 HydrophobicContact CB-CG2 3.95Å; L160-I165 HydrophobicContact CD1-CG2 3.84Å; L160-I165 HydrophobicContact CG-CG2 4.47Å; L160-R177 CarbonylContact C-O 3.6Å; L160-R177 VanDerWaalsContact CA-O 3.27Å; L160-R177 WeakPolarHBondContact CA-O 3.42Å; L160-R177 HydrophobicContact CD2-CB 4.41Å
161A90.3Very high90.4Very high0 Ų052.3 Ų52.30%033%0.328CS..  trans-77.5137.8174.100000110.1G163 G164 R177 L179A161-G163 PolarHBondContact O-N 3.34Å; A161-G164 PolarHBondContact O-N 2.81Å; A161-R177 PolarHBondContact N-O 3.06Å; A161-L179 HydrophobicContact CB-CB 4.24Å; A161-L179 HydrophobicContact CB-CD1 4.06Å
162P85.8Confident90.4Very high61 Ų6150.2 Ų50.240%0.39632%0.319SS..G310 helixtrans-57.3-33.3179.3-26.934.5000114.1G164 I165P162-G164 VanDerWaalsContact C-N 3.35Å; P162-I165 WeakPolarHBondContact O-CG1 3.43Å
163G84.5Confident90.5Very high26 Ų2651.7 Ų51.727%0.26833%0.325SS..G310 helixtrans-76.8-18.3176.200000114.3A161 Y171 L175A161-G163 PolarHBondContact O-N 3.34Å; G163-Y171 WeakPolarHBondContact O-CE1 3.34Å; G163-L175 WeakPolarHBondContact O-CD1 3.47Å
164G85.6Confident90.8Very high0 Ų047 Ų470%030%0.303CS..G310 helixtrans-95.712.8-173.300000115.1A161 P162 D172 G176 R177A161-G164 PolarHBondContact O-N 2.81Å; P162-G164 VanDerWaalsContact C-N 3.35Å; G164-D172 VanDerWaalsContact O-CG 3.24Å; G164-G176 VanDerWaalsContact CA-O 3.27Å; G164-G176 WeakPolarHBondContact CA-O 3.33Å; G164-R177 WeakPolarHBondContact O-CG 3.36Å; G164-R177 PolarHBondContact O-NH1 3.33Å
165I90Very high90.9Very high89 Ų8941.1 Ų41.146%0.45627%0.267SS..  trans-120.837.6-177.456.1168.9000111.8L160 P162 G167L160-I165 HydrophobicContact CB-CG2 3.95Å; L160-I165 HydrophobicContact CD1-CG2 3.84Å; L160-I165 HydrophobicContact CG-CG2 4.47Å; P162-I165 WeakPolarHBondContact O-CG1 3.43Å; I165-G167 VanDerWaalsContact C-N 3.28Å; I165-G167 PolarHBondContact O-N 3.36Å
166S89.3Confident91.2Very high24 Ų2440.4 Ų40.417%0.16826%0.262CS..SBendtrans-72-21.6-175.973.20000113.9N168 Y171 D172S166-N168 VanDerWaalsContact C-N 3.28Å; S166-N168 PolarHBondContact OG-N 2.88Å; S166-N168 VanDerWaalsContact OG-N 3.12Å; S166-Y171 VanDerWaalsContact OG-CD1 3.26Å; S166-Y171 WeakPolarHBondContact OG-CD1 3.42Å; S166-D172 VanDerWaalsContact CB-OD1 3.27Å; S166-D172 WeakPolarHBondContact CB-OD1 3.36Å; S166-D172 PolarHBondContact N-OD1 3.04Å; S166-D172 PolarHBondContact OG-OD1 2.94Å
167G88.4Confident91.5Very high67 Ų6738.7 Ų38.769%0.69125%0.245SC*.SBendtrans83.9-3-172.700000113.9I165 D172I165-G167 VanDerWaalsContact C-N 3.28Å; I165-G167 PolarHBondContact O-N 3.36Å; G167-D172 PolarHBondContact N-OD2 3.46Å
168N93.8Very high91.8Very high51 Ų5133.5 Ų33.527%0.27321%0.212SC..  trans-99.3117.8171.8-176.5-71.4000110.3P16 S166 I170 Y171 D172P16-N168 HydrophobicContact CB-CB 4.42Å; P16-N168 HydrophobicContact CG-CB 3.94Å; S166-N168 VanDerWaalsContact C-N 3.28Å; S166-N168 PolarHBondContact OG-N 2.88Å; S166-N168 VanDerWaalsContact OG-N 3.12Å; N168-I170 VanDerWaalsContact C-N 3.32Å; N168-I170 PolarHBondContact O-N 2.87Å; N168-I170 WeakPolarHBondContact OD1-CB 3.5Å; N168-I170 PolarHBondContact OD1-N 2.99Å; N168-Y171 PolarHBondContact O-N 3.29Å; N168-Y171 PolarHBondContact OD1-N 3.07Å; N168-Y171 VanDerWaalsContact OD1-N 3.1Å; N168-D172 WeakPolarHBondContact O-CB 3.29Å; N168-D172 PolarHBondContact O-N 3.41Å
169P94.3Very high92.1Very high78 Ų7831.8 Ų31.851%0.50620%0.198SC..Hα-helixtrans-59.1-36.7-175.9-27.935.5000114.9F173P169-F173 WeakPolarHBondContact O-CB 3.24Å; P169-F173 PolarHBondContact O-N 3.1Å
170I95.6Very high92.4Very high84 Ų8431.2 Ų31.243%0.43119%0.191SC..Hα-helixtrans-69.9-44.1-178.7-61.6172.1000110A20 L23 N168 F173 F174A20-I170 HydrophobicContact CB-CG2 3.87Å; L23-I170 HydrophobicContact CD1-CG2 3.87Å; N168-I170 VanDerWaalsContact C-N 3.32Å; N168-I170 PolarHBondContact O-N 2.87Å; N168-I170 WeakPolarHBondContact OD1-CB 3.5Å; N168-I170 PolarHBondContact OD1-N 2.99Å; I170-F173 PolarHBondContact O-N 3.43Å; I170-F174 WeakPolarHBondContact O-CB 3.42Å; I170-F174 PolarHBondContact O-N 3.23Å
171Y96Very high92.6Very high3 Ų330 Ų301%0.01219%0.185CC..Hα-helixtrans-66.5-45.2178.2-173.2-93.9000111.9L11 E12 G15 A19 G163 S166 N168 F173 F174 L175L11-Y171 HydrophobicContact CD2-CD1 4.2Å; L11-Y171 HydrophobicContact CD2-CE1 3.67Å; L11-Y171 HydrophobicContact CD2-CE2 4.31Å; E12-Y171 PolarHBondContact N-OH 2.96Å; E12-Y171 WeakPolarHBondContact O-CE2 3.36Å; G15-Y171 VanDerWaalsContact C-CD2 3.49Å; A19-Y171 HydrophobicContact CB-CD2 3.78Å; A19-Y171 HydrophobicContact CB-CE2 4.49Å; G163-Y171 WeakPolarHBondContact O-CE1 3.34Å; S166-Y171 VanDerWaalsContact OG-CD1 3.26Å; S166-Y171 WeakPolarHBondContact OG-CD1 3.42Å; N168-Y171 PolarHBondContact O-N 3.29Å; N168-Y171 PolarHBondContact OD1-N 3.07Å; N168-Y171 VanDerWaalsContact OD1-N 3.1Å; Y171-F173 VanDerWaalsContact C-N 3.31Å; Y171-F173 PolarHBondContact O-N 2.88Å; Y171-F174 WeakPolarHBondContact O-CB 3.19Å; Y171-F174 PolarHBondContact O-N 3.39Å; Y171-F174 VanDerWaalsContact O-N 3.14Å; Y171-L175 HydrophobicContact CD1-CD1 4.31Å; Y171-L175 HydrophobicContact CE1-CD1 3.43Å; Y171-L175 VanDerWaalsContact CE1-CD1 3.43Å; Y171-L175 HydrophobicContact CE1-CG 4.16Å; Y171-L175 HydrophobicContact CE2-CD1 4.35Å; Y171-L175 VanDerWaalsContact CZ-CD1 3.44Å; Y171-L175 PolarHBondContact O-N 2.82Å; Y171-L175 VanDerWaalsContact OH-CD1 3.27Å; Y171-L175 WeakPolarHBondContact OH-CD1 3.35Å
172D95.4Very high92.8Very high3 Ų332.1 Ų32.12%0.01619%0.193CC..Hα-helixtrans-68.1-29.9178.7-71.9-2.2000112.1Y149 G164 S166 G167 N168 G176 R177Y149-D172 HydrophobicContact CE2-CB 3.94Å; G164-D172 VanDerWaalsContact O-CG 3.24Å; S166-D172 VanDerWaalsContact CB-OD1 3.27Å; S166-D172 WeakPolarHBondContact CB-OD1 3.36Å; S166-D172 PolarHBondContact N-OD1 3.04Å; S166-D172 PolarHBondContact OG-OD1 2.94Å; G167-D172 PolarHBondContact N-OD2 3.46Å; N168-D172 WeakPolarHBondContact O-CB 3.29Å; N168-D172 PolarHBondContact O-N 3.41Å; D172-G176 CarbonylContact O-C 3.57Å; D172-G176 WeakPolarHBondContact O-CA 3.02Å; D172-G176 PolarHBondContact O-N 2.97Å; D172-R177 HydrophobicContact CB-CG 3.9Å; D172-R177 IonicContact OD2-NH1 3.81Å; D172-R177 PolarHBondContact OD2-NH1 2.91Å
173F96.8Very high93Very high34 Ų3433.3 Ų33.315%0.14920%0.195CC..Hα-helixtrans-67.5-41.9169.2173.9-91.4000111.9L23 F142 L146 Y149 P169 I170 Y171 F257L23-F173 HydrophobicContact CD1-CD1 4.27Å; L23-F173 HydrophobicContact CD2-CD1 4Å; L23-F173 HydrophobicContact CD2-CE1 3.79Å; F142-F173 HydrophobicContact CD1-CE1 4.43Å; F142-F173 HydrophobicContact CD1-CZ 4.26Å; L146-F173 HydrophobicContact CB-CE2 4.21Å; Y149-F173 HydrophobicContact CD2-CB 4Å; Y149-F173 HydrophobicContact CE2-CB 4.3Å; Y149-F173 HydrophobicContact CG-CD2 4.31Å; P169-F173 WeakPolarHBondContact O-CB 3.24Å; P169-F173 PolarHBondContact O-N 3.1Å; I170-F173 PolarHBondContact O-N 3.43Å; Y171-F173 VanDerWaalsContact C-N 3.31Å; Y171-F173 PolarHBondContact O-N 2.88Å; F173-F257 HydrophobicContact CD1-CB 4.11Å; F173-F257 HydrophobicContact CE1-CB 3.65Å; F173-F257 HydrophobicContact CE1-CD2 4.21Å; F173-F257 HydrophobicContact CE1-CG 4.11Å; F173-F257 HydrophobicContact CZ-CB 4.26Å; F173-F257 HydrophobicContact CZ-CD2 4.48Å; F173-F257 PolarHBondContact O-N 3.44Å
174F96.8Very high93.2Very high1 Ų137.5 Ų37.50%0.00422%0.219CC..Hα-helixtrans-66.7-53.3179.9179.4-99.5000112.1F13 A19 L22 L23 L26 I170 Y171 G256 F257 M258F13-F174 HydrophobicContact CB-CE1 4.27Å; F13-F174 HydrophobicContact CD1-CE1 4.39Å; F13-F174 HydrophobicContact CD2-CE1 4.26Å; F13-F174 HydrophobicContact CG-CE1 4.04Å; A19-F174 HydrophobicContact CB-CB 3.88Å; A19-F174 HydrophobicContact CB-CD1 3.79Å; A19-F174 HydrophobicContact CB-CG 3.82Å; L22-F174 HydrophobicContact CB-CE2 3.7Å; L22-F174 HydrophobicContact CB-CZ 3.82Å; L22-F174 HydrophobicContact CD1-CE1 4.29Å; L22-F174 HydrophobicContact CD1-CZ 3.8Å; L22-F174 HydrophobicContact CG-CZ 4.47Å; L23-F174 HydrophobicContact CD2-CD2 3.8Å; L23-F174 HydrophobicContact CG-CD2 4.05Å; L26-F174 HydrophobicContact CD1-CE2 4.28Å; I170-F174 WeakPolarHBondContact O-CB 3.42Å; I170-F174 PolarHBondContact O-N 3.23Å; Y171-F174 WeakPolarHBondContact O-CB 3.19Å; Y171-F174 PolarHBondContact O-N 3.39Å; Y171-F174 VanDerWaalsContact O-N 3.14Å; F174-G256 CarbonylContact O-C 3.57Å; F174-F257 HydrophobicContact CD2-CD1 4.19Å; F174-F257 HydrophobicContact CE2-CD1 4.39Å; F174-F257 PolarHBondContact O-N 3.47Å; F174-F257 VanDerWaalsContact O-N 3.16Å; F174-M258 HydrophobicContact CD1-CB 4.19Å; F174-M258 HydrophobicContact CD2-CB 4.28Å; F174-M258 HydrophobicContact CE1-CB 3.81Å; F174-M258 HydrophobicContact CE1-CG 3.93Å; F174-M258 HydrophobicContact CE1-SD 3.71Å; F174-M258 HydrophobicContact CE2-CB 3.91Å; F174-M258 HydrophobicContact CE2-CG 4.3Å; F174-M258 HydrophobicContact CG-CB 4.42Å; F174-M258 HydrophobicContact CZ-CB 3.65Å; F174-M258 HydrophobicContact CZ-CG 3.66Å; F174-M258 HydrophobicContact CZ-SD 3.97Å; F174-M258 VanDerWaalsContact O-CB 3.32Å; F174-M258 WeakPolarHBondContact O-CB 3.34Å; F174-M258 PolarHBondContact O-N 3.42Å
175L94.9Very high93.2Very high5 Ų543.2 Ų43.23%0.02624%0.244CC..Hα-helixtrans-75.3-34.7179-79-168.9000113.2F13 G163 Y171 G254 G256 M258F13-L175 HydrophobicContact CD2-CD2 3.81Å; F13-L175 HydrophobicContact CE2-CD2 3.64Å; G163-L175 WeakPolarHBondContact O-CD1 3.47Å; Y171-L175 HydrophobicContact CD1-CD1 4.31Å; Y171-L175 HydrophobicContact CE1-CD1 3.43Å; Y171-L175 VanDerWaalsContact CE1-CD1 3.43Å; Y171-L175 HydrophobicContact CE1-CG 4.16Å; Y171-L175 HydrophobicContact CE2-CD1 4.35Å; Y171-L175 VanDerWaalsContact CZ-CD1 3.44Å; Y171-L175 PolarHBondContact O-N 2.82Å; Y171-L175 VanDerWaalsContact OH-CD1 3.27Å; Y171-L175 WeakPolarHBondContact OH-CD1 3.35Å; L175-G254 CarbonylContact O-C 3.38Å; L175-G256 PolarHBondContact O-N 3.42Å; L175-M258 HydrophobicContact CD2-CE 3.91Å; L175-M258 HydrophobicContact CD2-SD 4.11Å
176G95.9Very high93.4Very high3 Ų340.4 Ų40.43%0.03123%0.229CC..  trans93.2136.6-173.100000112.4G164 D172 G254G164-G176 VanDerWaalsContact CA-O 3.27Å; G164-G176 WeakPolarHBondContact CA-O 3.33Å; D172-G176 CarbonylContact O-C 3.57Å; D172-G176 WeakPolarHBondContact O-CA 3.02Å; D172-G176 PolarHBondContact O-N 2.97Å; G176-G254 WeakPolarHBondContact O-CA 3.5Å
177R94.4Very high93.7Very high44 Ų4439.3 Ų39.317%0.16622%0.221CC..SBendtrans-85.6-43.8-175.5-65.8-176.657.276.80.9113.1Y149 A152 L160 A161 G164 D172Y149-R177 HydrophobicContact CD2-CG 4.13Å; Y149-R177 HydrophobicContact CE2-CG 4.14Å; A152-R177 HydrophobicContact CB-CB 3.5Å; A152-R177 HydrophobicContact CB-CG 4.37Å; L160-R177 CarbonylContact C-O 3.6Å; L160-R177 VanDerWaalsContact CA-O 3.27Å; L160-R177 WeakPolarHBondContact CA-O 3.42Å; L160-R177 HydrophobicContact CD2-CB 4.41Å; A161-R177 PolarHBondContact N-O 3.06Å; G164-R177 WeakPolarHBondContact O-CG 3.36Å; G164-R177 PolarHBondContact O-NH1 3.33Å; D172-R177 HydrophobicContact CB-CG 3.9Å; D172-R177 IonicContact OD2-NH1 3.81Å; D172-R177 PolarHBondContact OD2-NH1 2.91Å
178E94.6Very high94Very high18 Ų1837.4 Ų37.48%0.08419%0.194CC..BIsolated β-bridgetrans-86.5135.2-178.4-167.4171.4173.900109.9K151 A152 P181 F255K151-E178 IonicContact NZ-OE1 3.92Å; K151-E178 PolarHBondContact NZ-OE1 3.41Å; K151-E178 IonicContact NZ-OE2 2.96Å; K151-E178 PolarHBondContact NZ-OE2 3.31Å; A152-E178 HydrophobicContact CB-CB 4.23Å; E178-P181 HydrophobicContact CB-CB 4.22Å; E178-P181 VanDerWaalsContact CD-CA 3.44Å; E178-P181 HydrophobicContact CG-CB 4.06Å; E178-P181 WeakPolarHBondContact OE1-CA 3.2Å; E178-F255 PolarHBondContact O-N 2.69Å
179L93.2Very high94.1Very high23 Ų2335 Ų3512%0.1218%0.181CC..SBendtrans-67.5-58.4179.9-175.768.4000110L90 A159 A161 K189 D253L90-L179 HydrophobicContact CD2-CD2 4.12Å; A159-L179 PolarHBondContact O-N 2.77Å; A161-L179 HydrophobicContact CB-CB 4.24Å; A161-L179 HydrophobicContact CB-CD1 4.06Å; L179-K189 WeakPolarHBondContact O-CE 3.45Å; L179-K189 PolarHBondContact O-NZ 2.65Å; L179-D253 WeakPolarHBondContact CD1-O 3.32Å
180N93.8Very high94.1Very high16 Ų1631.3 Ų31.39%0.08616%0.157CC..SBendtrans-127.678.1-178.3-65.6-58000110.4L96 R182 I250L96-N180 HydrophobicContact CD1-CB 3.77Å; N180-R182 PolarHBondContact O-N 2.98Å; N180-I250 PolarHBondContact OD1-O 2.93Å
181P94.9Very high94.2Very high1 Ų127.9 Ų27.91%0.00614%0.139CC..  trans-65.4125.1-175.925.7-32.9000111.8L148 E178 F188 F255L148-P181 HydrophobicContact CD2-CB 3.72Å; L148-P181 HydrophobicContact CD2-CG 3.76Å; E178-P181 HydrophobicContact CB-CB 4.22Å; E178-P181 VanDerWaalsContact CD-CA 3.44Å; E178-P181 HydrophobicContact CG-CB 4.06Å; E178-P181 WeakPolarHBondContact OE1-CA 3.2Å; P181-F188 HydrophobicContact CB-CD2 4.26Å; P181-F188 HydrophobicContact CG-CB 4.41Å; P181-F188 VanDerWaalsContact O-CD2 3.27Å; P181-F188 WeakPolarHBondContact O-CD2 3.39Å; P181-F188 PolarHBondContact O-N 2.76Å; P181-F255 HydrophobicContact CG-CB 3.72Å; P181-F255 HydrophobicContact CG-CD1 3.73Å; P181-F255 HydrophobicContact CG-CG 4.18Å
182R93.9Very high94.2Very high43 Ų4328 Ų2816%0.16214%0.14CC..EExtended strand (participates in β ladder)trans-128.6149.4-175.5-74.8172.8179.4-129-6.3113.3R97 Y98 K151 N180 F186 D187R97-R182 PolarHBondContact O-NH1 3.43Å; R97-R182 VanDerWaalsContact O-NH1 3.12Å; Y98-R182 PolarHBondContact OH-NH2 3.44Å; K151-R182 VanDerWaalsContact CE-O 3.25Å; K151-R182 WeakPolarHBondContact CE-O 3.45Å; N180-R182 PolarHBondContact O-N 2.98Å; R182-F186 WeakPolarHBondContact CA-O 3.45Å; R182-D187 HydrophobicContact CG-CB 3.95Å; R182-D187 IonicContact CZ-OD2 3Å; R182-D187 IonicContact NE-OD2 3.09Å; R182-D187 PolarHBondContact NE-OD2 3.31Å; R182-D187 IonicContact NH2-OD2 2.75Å; R182-D187 PolarHBondContact NH2-OD2 2.84Å
183I91.9Very high94.1Very high87 Ų8729.2 Ų29.245%0.44615%0.145SC..EExtended strand (participates in β ladder)trans-120.3116.6156.7-62.7179.3000106.9F147 F185 F186 F188F147-I183 HydrophobicContact CZ-CD1 4.22Å; I183-F185 PolarHBondContact O-N 3.05Å; I183-F186 PolarHBondContact N-O 3.4Å; I183-F186 VanDerWaalsContact N-O 3.09Å; I183-F186 WeakPolarHBondContact O-CB 3.39Å; I183-F186 PolarHBondContact O-N 3.38Å; I183-F188 HydrophobicContact CB-CZ 4.37Å; I183-F188 HydrophobicContact CD1-CE2 3.97Å; I183-F188 HydrophobicContact CD1-CZ 3.62Å; I183-F188 HydrophobicContact CG1-CE2 3.75Å; I183-F188 HydrophobicContact CG1-CZ 3.8Å
184C88Confident93.8Very high114 Ų11427.6 Ų27.677%0.7714%0.139SC*.THydrogen-bonded Turntrans53.2-112.3-173.3-57.70000111.4
185F85.9Confident93.7Very high120 Ų12027.6 Ų27.653%0.52614%0.138SC..THydrogen-bonded Turntrans-101.20.7179.450.6-86.3000113.5L78 I183L78-F185 HydrophobicContact CD2-CD2 3.76Å; L78-F185 HydrophobicContact CD2-CE2 3.24Å; L78-F185 HydrophobicContact CD2-CZ 4.21Å; L78-F185 HydrophobicContact CG-CE2 4.47Å; I183-F185 PolarHBondContact O-N 3.05Å
186F93.2Very high93.8Very high30 Ų3027.4 Ų27.413%0.13214%0.137CC..EExtended strand (participates in β ladder)trans-87113.8177.8-160.5-70.9000109.8A74 Y77 L78 R182 I183 F188 F191A74-F186 HydrophobicContact CB-CE2 4.09Å; A74-F186 HydrophobicContact CB-CZ 4.43Å; Y77-F186 AromaticContact CD1-CD2 3.83Å; Y77-F186 HydrophobicContact CD1-CD2 3.83Å; Y77-F186 AromaticContact CD1-CE2 3.69Å; Y77-F186 HydrophobicContact CD1-CE2 3.69Å; Y77-F186 HydrophobicContact CD1-CZ 4.3Å; Y77-F186 AromaticContact CE1-CD2 3.96Å; Y77-F186 HydrophobicContact CE1-CD2 3.96Å; Y77-F186 HydrophobicContact CE1-CE2 4.17Å; Y77-F186 HydrophobicContact CE1-CG 4.21Å; Y77-F186 HydrophobicContact CG-CE2 4.44Å; L78-F186 HydrophobicContact CD1-CD2 4.48Å; L78-F186 HydrophobicContact CD2-CD2 3.87Å; L78-F186 HydrophobicContact CD2-CE2 4.49Å; L78-F186 HydrophobicContact CG-CD2 4.37Å; R182-F186 WeakPolarHBondContact CA-O 3.45Å; I183-F186 PolarHBondContact N-O 3.4Å; I183-F186 VanDerWaalsContact N-O 3.09Å; I183-F186 WeakPolarHBondContact O-CB 3.39Å; I183-F186 PolarHBondContact O-N 3.38Å; F186-F188 AromaticContact CD1-CD1 3.58Å; F186-F188 HydrophobicContact CD1-CD1 3.58Å; F186-F188 AromaticContact CD1-CE1 3.77Å; F186-F188 HydrophobicContact CD1-CE1 3.77Å; F186-F188 HydrophobicContact CD1-CG 4.3Å; F186-F188 AromaticContact CE1-CD1 3.58Å; F186-F188 HydrophobicContact CE1-CD1 3.58Å; F186-F188 AromaticContact CE1-CE1 3.98Å; F186-F188 HydrophobicContact CE1-CE1 3.98Å; F186-F191 HydrophobicContact CD1-CB 4.45Å; F186-F191 HydrophobicContact CE1-CB 3.51Å; F186-F191 AromaticContact CE1-CD1 3.71Å; F186-F191 HydrophobicContact CE1-CD1 3.71Å; F186-F191 HydrophobicContact CE1-CD2 4.2Å; F186-F191 HydrophobicContact CE1-CE1 4.48Å; F186-F191 AromaticContact CE1-CG 3.53Å; F186-F191 HydrophobicContact CE1-CG 3.53Å; F186-F191 HydrophobicContact CE2-CD2 4.26Å; F186-F191 HydrophobicContact CE2-CG 4.39Å; F186-F191 HydrophobicContact CZ-CB 3.74Å; F186-F191 AromaticContact CZ-CD1 3.53Å; F186-F191 HydrophobicContact CZ-CD1 3.53Å; F186-F191 AromaticContact CZ-CD2 3.51Å; F186-F191 HydrophobicContact CZ-CD2 3.51Å; F186-F191 AromaticContact CZ-CE1 3.94Å; F186-F191 HydrophobicContact CZ-CE1 3.94Å; F186-F191 AromaticContact CZ-CE2 3.94Å; F186-F191 HydrophobicContact CZ-CE2 3.94Å; F186-F191 AromaticContact CZ-CG 3.28Å; F186-F191 HydrophobicContact CZ-CG 3.28Å; F186-F191 HydrophobicContact CZ-CZ 4.13Å
187D95.3Very high93.8Very high0 Ų027.3 Ų27.30%014%0.136CC..EExtended strand (participates in β ladder)trans-98.1112.9174.3-171.8-59.9000108.8Y98 R182 K189 Y190 F191Y98-D187 HydrophobicContact CE1-CB 4.18Å; Y98-D187 WeakPolarHBondContact CE1-OD2 3.1Å; R182-D187 HydrophobicContact CG-CB 3.95Å; R182-D187 IonicContact CZ-OD2 3Å; R182-D187 IonicContact NE-OD2 3.09Å; R182-D187 PolarHBondContact NE-OD2 3.31Å; R182-D187 IonicContact NH2-OD2 2.75Å; R182-D187 PolarHBondContact NH2-OD2 2.84Å; D187-K189 PolarHBondContact OD1-N 2.71Å; D187-Y190 WeakPolarHBondContact OD1-CB 3.27Å; D187-Y190 PolarHBondContact OD1-N 3.21Å; D187-F191 WeakPolarHBondContact O-CB 3.48Å; D187-F191 PolarHBondContact O-N 3.23Å
188F95.9Very high93.9Very high27 Ų2726.2 Ų26.212%0.11813%0.134CC..Hα-helixtrans-68.2-40.1-172.6-71-57.8000112.8F144 F147 L148 P181 I183 F186 C192 F255F144-F188 HydrophobicContact CE1-CB 4.42Å; F144-F188 AromaticContact CE2-CD1 3.95Å; F144-F188 HydrophobicContact CE2-CD1 3.95Å; F144-F188 HydrophobicContact CE2-CE1 4.14Å; F144-F188 HydrophobicContact CE2-CG 4.17Å; F144-F188 HydrophobicContact CZ-CB 3.73Å; F144-F188 AromaticContact CZ-CD1 3.49Å; F144-F188 HydrophobicContact CZ-CD1 3.49Å; F144-F188 VanDerWaalsContact CZ-CD1 3.49Å; F144-F188 HydrophobicContact CZ-CD2 4.36Å; F144-F188 HydrophobicContact CZ-CE1 4.14Å; F144-F188 AromaticContact CZ-CG 3.62Å; F144-F188 HydrophobicContact CZ-CG 3.62Å; F147-F188 HydrophobicContact CE1-CE2 4.1Å; F147-F188 HydrophobicContact CE1-CZ 4.32Å; L148-F188 HydrophobicContact CD2-CD2 4.02Å; P181-F188 HydrophobicContact CB-CD2 4.26Å; P181-F188 HydrophobicContact CG-CB 4.41Å; P181-F188 VanDerWaalsContact O-CD2 3.27Å; P181-F188 WeakPolarHBondContact O-CD2 3.39Å; P181-F188 PolarHBondContact O-N 2.76Å; I183-F188 HydrophobicContact CB-CZ 4.37Å; I183-F188 HydrophobicContact CD1-CE2 3.97Å; I183-F188 HydrophobicContact CD1-CZ 3.62Å; I183-F188 HydrophobicContact CG1-CE2 3.75Å; I183-F188 HydrophobicContact CG1-CZ 3.8Å; F186-F188 AromaticContact CD1-CD1 3.58Å; F186-F188 HydrophobicContact CD1-CD1 3.58Å; F186-F188 AromaticContact CD1-CE1 3.77Å; F186-F188 HydrophobicContact CD1-CE1 3.77Å; F186-F188 HydrophobicContact CD1-CG 4.3Å; F186-F188 AromaticContact CE1-CD1 3.58Å; F186-F188 HydrophobicContact CE1-CD1 3.58Å; F186-F188 AromaticContact CE1-CE1 3.98Å; F186-F188 HydrophobicContact CE1-CE1 3.98Å; F188-C192 WeakPolarHBondContact O-CB 3.33Å; F188-C192 PolarHBondContact O-N 3.45Å; F188-C192 PolarHBondContact O-SG 2.98Å; F188-C192 VanDerWaalsContact O-SG 3.39Å; F188-F255 HydrophobicContact CB-CD1 4.12Å; F188-F255 HydrophobicContact CB-CE1 3.84Å
189K95.4Very high94.1Very high1 Ų125.5 Ų25.50%0.00413%0.131CC..Hα-helixtrans-63.1-55.5179.8-178.3-166.4-70.8178.50109.9L179 D187 F191 C192 E193 D249 I250 D253 F255 L259L179-K189 WeakPolarHBondContact O-CE 3.45Å; L179-K189 PolarHBondContact O-NZ 2.65Å; D187-K189 PolarHBondContact OD1-N 2.71Å; K189-F191 VanDerWaalsContact C-N 3.28Å; K189-F191 PolarHBondContact O-N 2.64Å; K189-C192 PolarHBondContact O-N 2.81Å; K189-E193 WeakPolarHBondContact O-CB 3.42Å; K189-E193 PolarHBondContact O-N 2.87Å; K189-D249 VanDerWaalsContact CD-O 3.27Å; K189-D249 WeakPolarHBondContact CD-O 3.41Å; K189-D249 WeakPolarHBondContact CE-O 3.32Å; K189-D249 PolarHBondContact NZ-O 2.88Å; K189-I250 HydrophobicContact CD-CD1 3.72Å; K189-I250 HydrophobicContact CG-CD1 4.11Å; K189-I250 PolarHBondContact NZ-O 3.27Å; K189-D253 WeakPolarHBondContact CE-O 3.28Å; K189-D253 PolarHBondContact NZ-O 3.21Å; K189-F255 HydrophobicContact CB-CB 3.99Å; K189-F255 HydrophobicContact CB-CD1 4.1Å; K189-F255 HydrophobicContact CB-CD2 3.71Å; K189-F255 HydrophobicContact CB-CE2 4.2Å; K189-F255 HydrophobicContact CB-CG 3.67Å; K189-F255 HydrophobicContact CG-CB 4.27Å; K189-F255 HydrophobicContact CG-CD2 3.59Å; K189-F255 HydrophobicContact CG-CE2 4.13Å; K189-F255 HydrophobicContact CG-CG 4.01Å; K189-L259 HydrophobicContact CD-CD1 4.49Å
190Y95.1Very high94.3Very high0 Ų024.7 Ų24.70%013%0.128CC..Hα-helixtrans-61.8-36.7-178.8179.6-105.7000112.8Y77 Y98 P99 I100 D187 L194 E241 L245 I250Y77-Y190 AromaticContact CE2-CD1 3.72Å; Y77-Y190 HydrophobicContact CE2-CD1 3.72Å; Y77-Y190 AromaticContact CE2-CE1 3.9Å; Y77-Y190 HydrophobicContact CE2-CE1 3.9Å; Y98-Y190 AromaticContact CD1-CD1 3.66Å; Y98-Y190 HydrophobicContact CD1-CD1 3.66Å; Y98-Y190 AromaticContact CD1-CD2 3.91Å; Y98-Y190 HydrophobicContact CD1-CD2 3.91Å; Y98-Y190 HydrophobicContact CD1-CE1 4.06Å; Y98-Y190 HydrophobicContact CD1-CE2 4.27Å; Y98-Y190 AromaticContact CD1-CG 3.56Å; Y98-Y190 HydrophobicContact CD1-CG 3.56Å; Y98-Y190 HydrophobicContact CE1-CD1 4.38Å; Y98-Y190 HydrophobicContact CE1-CD2 4.21Å; Y98-Y190 AromaticContact CE1-CG 3.89Å; Y98-Y190 HydrophobicContact CE1-CG 3.89Å; P99-Y190 HydrophobicContact CG-CE1 4.46Å; P99-Y190 PolarHBondContact O-OH 2.62Å; I100-Y190 VanDerWaalsContact CD1-OH 3.24Å; I100-Y190 WeakPolarHBondContact CD1-OH 3.07Å; D187-Y190 WeakPolarHBondContact OD1-CB 3.27Å; D187-Y190 PolarHBondContact OD1-N 3.21Å; Y190-L194 HydrophobicContact CD2-CD1 4.33Å; Y190-L194 HydrophobicContact CE2-CD1 3.76Å; Y190-E241 HydrophobicContact CE2-CG 4.49Å; Y190-E241 WeakPolarHBondContact OH-CG 3.32Å; Y190-E241 PolarHBondContact OH-OE1 2.74Å; Y190-L245 HydrophobicContact CD2-CD2 3.72Å; Y190-L245 HydrophobicContact CE2-CD2 3.45Å; Y190-L245 VanDerWaalsContact CE2-CD2 3.45Å; Y190-L245 HydrophobicContact CE2-CG 4.33Å; Y190-I250 HydrophobicContact CD2-CD1 4.21Å
191F96.1Very high94.5Very high12 Ų1223.9 Ų23.95%0.05312%0.124CC..Hα-helixtrans-62-52.7173.5170.8-104.9000111.7Q73 A74 Y77 F186 D187 K189 R195 P196Q73-F191 HydrophobicContact CB-CE2 4.03Å; Q73-F191 HydrophobicContact CB-CZ 3.96Å; A74-F191 HydrophobicContact CB-CE2 4.29Å; A74-F191 HydrophobicContact CB-CZ 4.12Å; Y77-F191 HydrophobicContact CD1-CD2 4.46Å; Y77-F191 AromaticContact CD2-CD2 3.97Å; Y77-F191 HydrophobicContact CD2-CD2 3.97Å; Y77-F191 HydrophobicContact CE2-CB 4.46Å; Y77-F191 AromaticContact CG-CD2 3.87Å; Y77-F191 HydrophobicContact CG-CD2 3.87Å; F186-F191 HydrophobicContact CD1-CB 4.45Å; F186-F191 HydrophobicContact CE1-CB 3.51Å; F186-F191 AromaticContact CE1-CD1 3.71Å; F186-F191 HydrophobicContact CE1-CD1 3.71Å; F186-F191 HydrophobicContact CE1-CD2 4.2Å; F186-F191 HydrophobicContact CE1-CE1 4.48Å; F186-F191 AromaticContact CE1-CG 3.53Å; F186-F191 HydrophobicContact CE1-CG 3.53Å; F186-F191 HydrophobicContact CE2-CD2 4.26Å; F186-F191 HydrophobicContact CE2-CG 4.39Å; F186-F191 HydrophobicContact CZ-CB 3.74Å; F186-F191 AromaticContact CZ-CD1 3.53Å; F186-F191 HydrophobicContact CZ-CD1 3.53Å; F186-F191 AromaticContact CZ-CD2 3.51Å; F186-F191 HydrophobicContact CZ-CD2 3.51Å; F186-F191 AromaticContact CZ-CE1 3.94Å; F186-F191 HydrophobicContact CZ-CE1 3.94Å; F186-F191 AromaticContact CZ-CE2 3.94Å; F186-F191 HydrophobicContact CZ-CE2 3.94Å; F186-F191 AromaticContact CZ-CG 3.28Å; F186-F191 HydrophobicContact CZ-CG 3.28Å; F186-F191 HydrophobicContact CZ-CZ 4.13Å; D187-F191 WeakPolarHBondContact O-CB 3.48Å; D187-F191 PolarHBondContact O-N 3.23Å; K189-F191 VanDerWaalsContact C-N 3.28Å; K189-F191 PolarHBondContact O-N 2.64Å; F191-R195 HydrophobicContact CD2-CB 3.89Å; F191-R195 HydrophobicContact CD2-CG 3.83Å; F191-R195 HydrophobicContact CE2-CB 3.75Å; F191-R195 HydrophobicContact CE2-CG 4.07Å; F191-R195 HydrophobicContact CZ-CB 4.44Å; F191-R195 VanDerWaalsContact O-CB 3.31Å; F191-R195 WeakPolarHBondContact O-CB 3.32Å; F191-R195 PolarHBondContact O-N 3.04Å; F191-P196 HydrophobicContact CE1-CG 4.03Å; F191-P196 HydrophobicContact CZ-CG 4.37Å; F191-P196 WeakPolarHBondContact O-CD 3.35Å
192C96.5Very high94.7Very high5 Ų525 Ų253%0.03413%0.13CC..Hα-helixtrans-63.2-45.5-176.5-77.60000112.4F188 K189 L194 F255 D263 I264F188-C192 WeakPolarHBondContact O-CB 3.33Å; F188-C192 PolarHBondContact O-N 3.45Å; F188-C192 PolarHBondContact O-SG 2.98Å; F188-C192 VanDerWaalsContact O-SG 3.39Å; K189-C192 PolarHBondContact O-N 2.81Å; C192-L194 PolarHBondContact O-N 3.12Å; C192-L194 VanDerWaalsContact O-N 3.16Å; C192-F255 HydrophobicContact CB-CE2 4.25Å; C192-F255 HydrophobicContact CB-CZ 3.67Å; C192-D263 HydrophobicContact CB-CB 3.96Å; C192-I264 HydrophobicContact CB-CG2 4.12Å
193E93.9Very high94.9Very high29 Ų2924.2 Ų24.214%0.13613%0.129CC..Hα-helixtrans-55.4-35.7-176.9-171.2175-173.200112.5K189 I250 D263K189-E193 WeakPolarHBondContact O-CB 3.42Å; K189-E193 PolarHBondContact O-N 2.87Å; E193-I250 WeakPolarHBondContact OE2-CD1 3.26Å; E193-I250 WeakPolarHBondContact OE2-CG1 3.08Å; E193-D263 PolarHBondContact N-OD2 3.12Å
194L90.8Very high95.2Very high1 Ų120.6 Ų20.61%0.00511%0.111CC..Hα-helixtrans-111.1-36.9-172.2-78.7172.4000115.6Y190 C192 L198 L238 E241 I244Y190-L194 HydrophobicContact CD2-CD1 4.33Å; Y190-L194 HydrophobicContact CE2-CD1 3.76Å; C192-L194 PolarHBondContact O-N 3.12Å; C192-L194 VanDerWaalsContact O-N 3.16Å; L194-L198 HydrophobicContact CD2-CD1 3.71Å; L194-L238 HydrophobicContact CB-CD2 4.25Å; L194-L238 HydrophobicContact CD2-CD2 3.85Å; L194-E241 HydrophobicContact CD1-CG 3.73Å; L194-I244 HydrophobicContact CD1-CD1 3.77Å; L194-I244 HydrophobicContact CD2-CD1 3.16Å; L194-I244 HydrophobicContact CG-CD1 3.77Å
195R94.6Very high95.7Very high0 Ų015.3 Ų15.30%08%0.075CC..Iπ-helixtrans-90.9-77.5-164.4-56.6-65.4-169.4-81.6-4.5112.2Q73 Y77 N101 F191 G197 I199 E241Q73-R195 HydrophobicContact CB-CB 4.26Å; Y77-R195 HydrophobicContact CD2-CG 4.37Å; N101-R195 PolarHBondContact OD1-NH2 2.66Å; F191-R195 HydrophobicContact CD2-CB 3.89Å; F191-R195 HydrophobicContact CD2-CG 3.83Å; F191-R195 HydrophobicContact CE2-CB 3.75Å; F191-R195 HydrophobicContact CE2-CG 4.07Å; F191-R195 HydrophobicContact CZ-CB 4.44Å; F191-R195 VanDerWaalsContact O-CB 3.31Å; F191-R195 WeakPolarHBondContact O-CB 3.32Å; F191-R195 PolarHBondContact O-N 3.04Å; R195-G197 VanDerWaalsContact C-N 3.26Å; R195-G197 PolarHBondContact O-N 3.1Å; R195-I199 VanDerWaalsContact O-CB 3.28Å; R195-I199 WeakPolarHBondContact O-CB 3.14Å; R195-I199 WeakPolarHBondContact O-CG1 3.25Å; R195-I199 PolarHBondContact O-N 3.07Å; R195-E241 IonicContact CZ-OE1 2.86Å; R195-E241 IonicContact NH1-OE1 3.95Å; R195-E241 PolarHBondContact NH1-OE1 2.86Å; R195-E241 IonicContact NH2-OE1 2.73Å; R195-E241 PolarHBondContact NH2-OE1 2.82Å; R195-E241 IonicContact NH2-OE2 2.74Å
196P96.2Very high96.3Very high1 Ų112.8 Ų12.81%0.0067%0.066CC..Iπ-helixtrans-66.6-29-171.831.2-37.7000112.9W69 L70 F191 G200 I264W69-P196 PolarHBondContact NE1-O 3.24Å; W69-P196 VanDerWaalsContact NE1-O 3.09Å; L70-P196 HydrophobicContact CD2-CB 3.64Å; L70-P196 HydrophobicContact CD2-CG 4.25Å; F191-P196 HydrophobicContact CE1-CG 4.03Å; F191-P196 HydrophobicContact CZ-CG 4.37Å; F191-P196 WeakPolarHBondContact O-CD 3.35Å; P196-G200 WeakPolarHBondContact O-CA 3.35Å; P196-G200 PolarHBondContact O-N 3.44Å; P196-I264 HydrophobicContact CG-CG2 4.09Å
197G95.7Very high96.5Very high1 Ų111.4 Ų11.41%0.016%0.06CC..Iπ-helixtrans-75.4-70179.400000113.4R195 G200 W201 D263R195-G197 VanDerWaalsContact C-N 3.26Å; R195-G197 PolarHBondContact O-N 3.1Å; G197-G200 PolarHBondContact O-N 2.94Å; G197-W201 PolarHBondContact O-N 2.83Å; G197-D263 WeakPolarHBondContact CA-O 3.16Å
198L97.3Very high96.7Very high22 Ų2211.5 Ų11.512%0.1156%0.061CC..Iπ-helixtrans-66.4-42.1-174.1-64.2177.2000113.4L194 G200 W201 V202 V234 V267L194-L198 HydrophobicContact CD2-CD1 3.71Å; L198-G200 VanDerWaalsContact C-N 3.27Å; L198-G200 PolarHBondContact O-N 3.43Å; L198-W201 HydrophobicContact CD2-CE3 4.09Å; L198-W201 HydrophobicContact CD2-CZ3 4.37Å; L198-W201 WeakPolarHBondContact O-CB 3.46Å; L198-W201 PolarHBondContact O-N 3.49Å; L198-V202 PolarHBondContact O-N 3.26Å; L198-V234 HydrophobicContact CB-CG1 3.98Å; L198-V234 HydrophobicContact CB-CG2 4.38Å; L198-V234 HydrophobicContact CD2-CG2 4.42Å; L198-V267 HydrophobicContact CD2-CG1 3.89Å
199I98.2Very high96.7Very high2 Ų210.9 Ų10.91%0.016%0.059CC..Iπ-helixtrans-69.6-33.6176.2-52.9176.9000109.6W69 A105 L106 T109 R195 W201 V202 L203 L238W69-I199 HydrophobicContact CH2-CB 4.15Å; W69-I199 HydrophobicContact CH2-CG2 3.72Å; W69-I199 HydrophobicContact CZ2-CB 4.14Å; W69-I199 HydrophobicContact CZ2-CG2 4.23Å; A105-I199 HydrophobicContact CB-CD1 4.05Å; L106-I199 HydrophobicContact CB-CD1 4.48Å; L106-I199 HydrophobicContact CD1-CG2 3.92Å; T109-I199 HydrophobicContact CG2-CG2 4.07Å; R195-I199 VanDerWaalsContact O-CB 3.28Å; R195-I199 WeakPolarHBondContact O-CB 3.14Å; R195-I199 WeakPolarHBondContact O-CG1 3.25Å; R195-I199 PolarHBondContact O-N 3.07Å; I199-W201 VanDerWaalsContact C-N 3.35Å; I199-V202 PolarHBondContact O-N 3.43Å; I199-L203 PolarHBondContact O-N 3.36Å; I199-L238 HydrophobicContact CD1-CD1 4.26Å; I199-L238 HydrophobicContact CG1-CD1 3.85Å
200G97.9Very high96.8Very high6 Ų612.7 Ų12.76%0.0627%0.07CC..Hα-helixtrans-65-39175.900000112.2W69 P196 G197 L198 V202 L203 I204W69-G200 VanDerWaalsContact CZ2-CA 3.44Å; W69-G200 VanDerWaalsContact CZ2-N 3.33Å; P196-G200 WeakPolarHBondContact O-CA 3.35Å; P196-G200 PolarHBondContact O-N 3.44Å; G197-G200 PolarHBondContact O-N 2.94Å; L198-G200 VanDerWaalsContact C-N 3.27Å; L198-G200 PolarHBondContact O-N 3.43Å; G200-V202 PolarHBondContact O-N 2.88Å; G200-L203 PolarHBondContact O-N 3.18Å; G200-I204 WeakPolarHBondContact O-CG1 3.33Å; G200-I204 PolarHBondContact O-N 3.35Å
201W98.4Very high96.9Very high0 Ų014.6 Ų14.60%08%0.078CC..Hα-helixtrans-57.2-48.7172.7174.624.8000111.8G197 L198 I199 L203 I204 N205 Q230 Y233 V234 P268 Y271 W361G197-W201 PolarHBondContact O-N 2.83Å; L198-W201 HydrophobicContact CD2-CE3 4.09Å; L198-W201 HydrophobicContact CD2-CZ3 4.37Å; L198-W201 WeakPolarHBondContact O-CB 3.46Å; L198-W201 PolarHBondContact O-N 3.49Å; I199-W201 VanDerWaalsContact C-N 3.35Å; W201-L203 VanDerWaalsContact C-N 3.32Å; W201-L203 PolarHBondContact O-N 2.87Å; W201-I204 PolarHBondContact O-N 3.12Å; W201-N205 PolarHBondContact NE1-ND2 3.01Å; W201-N205 WeakPolarHBondContact O-CB 3.27Å; W201-N205 PolarHBondContact O-N 3.32Å; W201-Q230 HydrophobicContact CH2-CB 4.02Å; W201-Q230 HydrophobicContact CH2-CG 4.1Å; W201-Q230 HydrophobicContact CZ2-CB 3.51Å; W201-Q230 HydrophobicContact CZ2-CG 3.43Å; W201-Q230 VanDerWaalsContact CZ2-CG 3.43Å; W201-Q230 VanDerWaalsContact NE1-OE1 3.11Å; W201-Y233 HydrophobicContact CH2-CD1 4.16Å; W201-Y233 AromaticContact CZ3-CD1 3.92Å; W201-Y233 HydrophobicContact CZ3-CD1 3.92Å; W201-Y233 HydrophobicContact CZ3-CE1 4.4Å; W201-V234 HydrophobicContact CD2-CG2 4.17Å; W201-V234 HydrophobicContact CE3-CG2 3.24Å; W201-V234 HydrophobicContact CH2-CG2 4.34Å; W201-V234 HydrophobicContact CZ3-CG2 3.34Å; W201-P268 HydrophobicContact CB-CB 4.42Å; W201-Y271 VanDerWaalsContact CE2-CB 3.48Å; W201-Y271 HydrophobicContact CE3-CD2 4.25Å; W201-Y271 AromaticContact CH2-CD2 4Å; W201-Y271 HydrophobicContact CH2-CD2 4Å; W201-Y271 HydrophobicContact CZ2-CD2 4.22Å; W201-Y271 HydrophobicContact CZ2-CG 4.48Å; W201-Y271 HydrophobicContact CZ3-CD2 4Å; W201-Y271 PolarHBondContact NE1-O 3.49Å; W201-Y271 VanDerWaalsContact NE1-O 3.08Å; W201-W361 HydrophobicContact CH2-CE3 4.5Å; W201-W361 AromaticContact CH2-CH2 3.97Å; W201-W361 HydrophobicContact CH2-CH2 3.97Å; W201-W361 AromaticContact CH2-CZ3 3.7Å; W201-W361 HydrophobicContact CH2-CZ3 3.7Å; W201-W361 HydrophobicContact CZ2-CZ3 4.12Å
202V98.4Very high97Very high23 Ų2314 Ų1414%0.1398%0.075CC..Hα-helixtrans-60.6-41.6176.3173.70000111.5L106 L198 I199 G200 N205 L206 L231 V234L106-V202 HydrophobicContact CD1-CG1 4.28Å; L198-V202 PolarHBondContact O-N 3.26Å; I199-V202 PolarHBondContact O-N 3.43Å; G200-V202 PolarHBondContact O-N 2.88Å; V202-N205 WeakPolarHBondContact O-CB 3.45Å; V202-N205 PolarHBondContact O-N 3.37Å; V202-L206 WeakPolarHBondContact O-CB 3.45Å; V202-L206 PolarHBondContact O-N 2.98Å; V202-L231 HydrophobicContact CG1-CD1 3.72Å; V202-L231 HydrophobicContact CG2-CD1 4.18Å; V202-V234 HydrophobicContact CG2-CB 3.71Å; V202-V234 HydrophobicContact CG2-CG1 3.66Å; V202-V234 HydrophobicContact CG2-CG2 3.84Å
203L98.1Very high97Very high27 Ų2715.1 Ų15.114%0.1419%0.085CC..Hα-helixtrans-63.9-43.7178.3179.660.4000112.3W69 V113 L123 I199 G200 W201 N205 L206 A207W69-L203 HydrophobicContact CE3-CD2 3.93Å; W69-L203 HydrophobicContact CH2-CD2 4.13Å; W69-L203 HydrophobicContact CZ3-CD2 3.64Å; V113-L203 HydrophobicContact CG1-CD1 4.07Å; V113-L203 HydrophobicContact CG2-CD1 3.88Å; L123-L203 HydrophobicContact CD1-CD1 4.02Å; I199-L203 PolarHBondContact O-N 3.36Å; G200-L203 PolarHBondContact O-N 3.18Å; W201-L203 VanDerWaalsContact C-N 3.32Å; W201-L203 PolarHBondContact O-N 2.87Å; L203-N205 VanDerWaalsContact C-N 3.34Å; L203-L206 PolarHBondContact O-N 3.47Å; L203-A207 WeakPolarHBondContact O-CB 3.42Å; L203-A207 PolarHBondContact O-N 2.81Å
204I98.4Very high97.1Very high12 Ų1218.8 Ų18.86%0.06210%0.102CC..Hα-helixtrans-61.1-45.9176.4-71.7168.9000110.2L126 L130 G200 W201 L206 A207 L208 P268 F269L126-I204 HydrophobicContact CD2-CG1 4.11Å; L130-I204 HydrophobicContact CD1-CG2 4.34Å; L130-I204 HydrophobicContact CD2-CB 4.48Å; L130-I204 HydrophobicContact CD2-CD1 3.99Å; L130-I204 HydrophobicContact CD2-CG1 3.92Å; L130-I204 HydrophobicContact CD2-CG2 3.78Å; G200-I204 WeakPolarHBondContact O-CG1 3.33Å; G200-I204 PolarHBondContact O-N 3.35Å; W201-I204 PolarHBondContact O-N 3.12Å; I204-L206 PolarHBondContact O-N 2.81Å; I204-A207 WeakPolarHBondContact O-CB 2.91Å; I204-A207 PolarHBondContact O-N 2.69Å; I204-L208 HydrophobicContact CG2-CD1 3.75Å; I204-L208 HydrophobicContact CG2-CG 4.41Å; I204-L208 VanDerWaalsContact O-CG 3.31Å; I204-L208 WeakPolarHBondContact O-CG 3.49Å; I204-L208 PolarHBondContact O-N 3.36Å; I204-P268 HydrophobicContact CD1-CB 3.81Å; I204-F269 HydrophobicContact CD1-CD1 4.02Å; I204-F269 HydrophobicContact CD1-CE1 3.88Å; I204-F269 HydrophobicContact CD1-CZ 4.48Å
205N98.4Very high97.3Very high3 Ų323.7 Ų23.72%0.01613%0.128CC..Hα-helixtrans-57.9-48.9176.4-85-8.2000112.2W201 V202 L203 A207 L208 L209 N227 Q230 S272W201-N205 PolarHBondContact NE1-ND2 3.01Å; W201-N205 WeakPolarHBondContact O-CB 3.27Å; W201-N205 PolarHBondContact O-N 3.32Å; V202-N205 WeakPolarHBondContact O-CB 3.45Å; V202-N205 PolarHBondContact O-N 3.37Å; L203-N205 VanDerWaalsContact C-N 3.34Å; N205-A207 VanDerWaalsContact C-N 3.28Å; N205-A207 PolarHBondContact O-N 3.01Å; N205-L208 WeakPolarHBondContact O-CB 3.49Å; N205-L208 PolarHBondContact O-N 3.12Å; N205-L208 VanDerWaalsContact O-N 3.12Å; N205-L209 PolarHBondContact O-N 3.05Å; N205-N227 WeakPolarHBondContact CB-OD1 3.45Å; N205-N227 PolarHBondContact O-OD1 3.21Å; N205-Q230 PolarHBondContact ND2-OE1 3.24Å; N205-S272 VanDerWaalsContact OD1-CB 3.27Å; N205-S272 WeakPolarHBondContact OD1-CB 3.27Å
206L98Very high97.3Very high67 Ų6728.5 Ų28.535%0.35115%0.146SC..Hα-helixtrans-58.3-42176.5-179.862.9000111.5V113 L123 V202 L203 I204 L208 L209 V210V113-L206 HydrophobicContact CG1-CD2 4.42Å; L123-L206 HydrophobicContact CD2-CD2 3.95Å; L123-L206 HydrophobicContact CD2-CG 3.91Å; V202-L206 WeakPolarHBondContact O-CB 3.45Å; V202-L206 PolarHBondContact O-N 2.98Å; L203-L206 PolarHBondContact O-N 3.47Å; I204-L206 PolarHBondContact O-N 2.81Å; L206-L208 PolarHBondContact O-N 2.93Å; L206-L209 PolarHBondContact O-N 3.12Å; L206-V210 HydrophobicContact CD1-CG2 4.47Å; L206-V210 WeakPolarHBondContact O-CG2 3.05Å; L206-V210 PolarHBondContact O-N 3.3Å
207A98.2Very high97.2Very high0 Ų031.9 Ų31.90%018%0.181CC..Hα-helixtrans-65.1-37.7177.300000112.9L123 L126 P127 L203 I204 N205 K211L123-A207 HydrophobicContact CD1-CB 3.94Å; L123-A207 HydrophobicContact CG-CB 3.92Å; L126-A207 HydrophobicContact CB-CB 3.93Å; L126-A207 HydrophobicContact CD2-CB 3.94Å; L126-A207 HydrophobicContact CG-CB 4.35Å; P127-A207 HydrophobicContact CG-CB 4.31Å; L203-A207 WeakPolarHBondContact O-CB 3.42Å; L203-A207 PolarHBondContact O-N 2.81Å; I204-A207 WeakPolarHBondContact O-CB 2.91Å; I204-A207 PolarHBondContact O-N 2.69Å; N205-A207 VanDerWaalsContact C-N 3.28Å; N205-A207 PolarHBondContact O-N 3.01Å; A207-K211 VanDerWaalsContact O-CB 3.29Å; A207-K211 WeakPolarHBondContact O-CB 3.4Å; A207-K211 PolarHBondContact O-N 3.05Å
208L98.2Very high97.2Very high2 Ų235.5 Ų35.51%0.0121%0.206CC..Hα-helixtrans-66-40.1173.6-70.1161.8000111.8P127 L130 I204 N205 L206 K211 E212 A275 Q276 L279P127-L208 HydrophobicContact CB-CD2 3.75Å; P127-L208 HydrophobicContact CG-CD2 3.79Å; P127-L208 HydrophobicContact CG-CG 4.16Å; L130-L208 HydrophobicContact CD1-CD2 4.37Å; I204-L208 HydrophobicContact CG2-CD1 3.75Å; I204-L208 HydrophobicContact CG2-CG 4.41Å; I204-L208 VanDerWaalsContact O-CG 3.31Å; I204-L208 WeakPolarHBondContact O-CG 3.49Å; I204-L208 PolarHBondContact O-N 3.36Å; N205-L208 WeakPolarHBondContact O-CB 3.49Å; N205-L208 PolarHBondContact O-N 3.12Å; N205-L208 VanDerWaalsContact O-N 3.12Å; L206-L208 PolarHBondContact O-N 2.93Å; L208-K211 PolarHBondContact O-N 2.91Å; L208-E212 PolarHBondContact O-N 3.28Å; L208-A275 HydrophobicContact CB-CB 4.18Å; L208-A275 HydrophobicContact CD1-CB 3.69Å; L208-Q276 HydrophobicContact CD1-CB 4.44Å; L208-Q276 HydrophobicContact CD1-CG 3.58Å; L208-Q276 HydrophobicContact CD2-CG 4.14Å; L208-L279 HydrophobicContact CD2-CD2 3.75Å
209L97.7Very high97.1Very high14 Ų1435.5 Ų35.57%0.07321%0.208CC..Hα-helixtrans-64.2-46.6175.7-178149.3000111.6N205 L206 K211 E212 A213 P219 M223 W224 N227N205-L209 PolarHBondContact O-N 3.05Å; L206-L209 PolarHBondContact O-N 3.12Å; L209-K211 VanDerWaalsContact C-N 3.32Å; L209-K211 PolarHBondContact O-N 3.33Å; L209-E212 PolarHBondContact O-N 2.69Å; L209-A213 PolarHBondContact O-N 3.32Å; L209-P219 HydrophobicContact CD2-CB 4.37Å; L209-P219 HydrophobicContact CD2-CG 3.7Å; L209-P219 HydrophobicContact CG-CB 4Å; L209-P219 HydrophobicContact CG-CG 3.9Å; L209-M223 HydrophobicContact CB-CG 4.1Å; L209-M223 HydrophobicContact CD1-CG 4.31Å; L209-M223 HydrophobicContact CG-CG 4.15Å; L209-W224 HydrophobicContact CD1-CD2 4.09Å; L209-W224 HydrophobicContact CD1-CE3 3.73Å; L209-W224 HydrophobicContact CD1-CH2 4.23Å; L209-W224 HydrophobicContact CD1-CZ3 3.81Å; L209-W224 HydrophobicContact CD2-CH2 4.17Å; L209-W224 HydrophobicContact CD2-CZ2 4.39Å; L209-N227 HydrophobicContact CD1-CB 3.87Å
210V97.3Very high97Very high39 Ų3937 Ų3724%0.23622%0.218CC..Hα-helixtrans-61.6-42.6174.91700000110.5L123 L206 E212 A213 E214L123-V210 HydrophobicContact CD2-CG2 4.26Å; L206-V210 HydrophobicContact CD1-CG2 4.47Å; L206-V210 WeakPolarHBondContact O-CG2 3.05Å; L206-V210 PolarHBondContact O-N 3.3Å; V210-E212 VanDerWaalsContact C-N 3.33Å; V210-E212 PolarHBondContact O-N 2.83Å; V210-A213 WeakPolarHBondContact O-CB 3.41Å; V210-A213 PolarHBondContact O-N 3.48Å; V210-A213 VanDerWaalsContact O-N 3.13Å; V210-E214 HydrophobicContact CG1-CG 4.48Å; V210-E214 WeakPolarHBondContact O-CG 3.43Å; V210-E214 PolarHBondContact O-N 3.3Å
211K97.4Very high97Very high40 Ų4039.7 Ų39.717%0.17423%0.231CC..Hα-helixtrans-63-39.3177.8-17347.3158.9-166.40112.7G124 P127 A207 L208 L209 A213 E214 L215 L279G124-K211 WeakPolarHBondContact O-CD 3.44Å; G124-K211 WeakPolarHBondContact O-CE 3.33Å; P127-K211 HydrophobicContact CG-CB 3.91Å; P127-K211 HydrophobicContact CG-CG 4.24Å; A207-K211 VanDerWaalsContact O-CB 3.29Å; A207-K211 WeakPolarHBondContact O-CB 3.4Å; A207-K211 PolarHBondContact O-N 3.05Å; L208-K211 PolarHBondContact O-N 2.91Å; L209-K211 VanDerWaalsContact C-N 3.32Å; L209-K211 PolarHBondContact O-N 3.33Å; K211-A213 VanDerWaalsContact C-N 3.34Å; K211-E214 VanDerWaalsContact CD-OE2 3.29Å; K211-E214 WeakPolarHBondContact CD-OE2 3.48Å; K211-E214 IonicContact NZ-OE2 2.93Å; K211-E214 PolarHBondContact NZ-OE2 3.44Å; K211-E214 VanDerWaalsContact NZ-OE2 3.09Å; K211-E214 PolarHBondContact O-N 3.11Å; K211-L215 HydrophobicContact CD-CD1 4.43Å; K211-L215 HydrophobicContact CD-CG 4.34Å; K211-L215 HydrophobicContact CG-CD1 4.35Å; K211-L215 VanDerWaalsContact O-CG 3.31Å; K211-L215 WeakPolarHBondContact O-CG 3.28Å; K211-L215 PolarHBondContact O-N 3.49Å; K211-L215 VanDerWaalsContact O-N 3.13Å; K211-L279 HydrophobicContact CB-CD1 4.19Å; K211-L279 HydrophobicContact CB-CD2 4.38Å; K211-L279 HydrophobicContact CG-CD1 4.03Å; K211-L279 HydrophobicContact CG-CD2 3.95Å
212E97Very high97Very high0 Ų039.7 Ų39.70%023%0.231CC..Hα-helixtrans-62.4-43.4172.8176.2164.3-103.600111.6L208 L209 V210 E214 L215 R216 S220 M223 L279L208-E212 PolarHBondContact O-N 3.28Å; L209-E212 PolarHBondContact O-N 2.69Å; V210-E212 VanDerWaalsContact C-N 3.33Å; V210-E212 PolarHBondContact O-N 2.83Å; E212-E214 VanDerWaalsContact C-N 3.34Å; E212-E214 PolarHBondContact O-N 3.17Å; E212-L215 PolarHBondContact O-N 2.92Å; E212-R216 WeakPolarHBondContact O-CB 3.3Å; E212-R216 PolarHBondContact O-N 3.01Å; E212-R216 IonicContact OE1-CZ 3.55Å; E212-R216 IonicContact OE1-NH1 2.93Å; E212-R216 PolarHBondContact OE1-NH1 3.01Å; E212-S220 WeakPolarHBondContact OE2-CB 3.3Å; E212-S220 PolarHBondContact OE2-N 2.89Å; E212-S220 PolarHBondContact OE2-OG 3.01Å; E212-M223 HydrophobicContact CB-CE 4.07Å; E212-M223 WeakPolarHBondContact OE2-CB 3.45Å; E212-M223 WeakPolarHBondContact OE2-CG 3.32Å; E212-L279 HydrophobicContact CB-CD1 3.79Å
213A96.5Very high97Very high28 Ų2838.6 Ų38.623%0.23122%0.224CC..Hα-helixtrans-59.7-42.6176.400000112.3L209 V210 K211 L215 R216 G217 P219L209-A213 PolarHBondContact O-N 3.32Å; V210-A213 WeakPolarHBondContact O-CB 3.41Å; V210-A213 PolarHBondContact O-N 3.48Å; V210-A213 VanDerWaalsContact O-N 3.13Å; K211-A213 VanDerWaalsContact C-N 3.34Å; A213-L215 VanDerWaalsContact C-N 3.33Å; A213-L215 PolarHBondContact O-N 2.85Å; A213-R216 PolarHBondContact O-N 3.06Å; A213-G217 CarbonylContact O-C 3.38Å; A213-G217 WeakPolarHBondContact O-CA 3.44Å; A213-G217 PolarHBondContact O-N 3.47Å; A213-P219 HydrophobicContact CB-CG 3.95Å
214E95.9Very high97Very high106 Ų10644 Ų4450%0.49524%0.243SC..Hα-helixtrans-60.7-40.7175.7-71.9173.3-178.200112.3V210 K211 E212V210-E214 HydrophobicContact CG1-CG 4.48Å; V210-E214 WeakPolarHBondContact O-CG 3.43Å; V210-E214 PolarHBondContact O-N 3.3Å; K211-E214 VanDerWaalsContact CD-OE2 3.29Å; K211-E214 WeakPolarHBondContact CD-OE2 3.48Å; K211-E214 IonicContact NZ-OE2 2.93Å; K211-E214 PolarHBondContact NZ-OE2 3.44Å; K211-E214 VanDerWaalsContact NZ-OE2 3.09Å; K211-E214 PolarHBondContact O-N 3.11Å; E212-E214 VanDerWaalsContact C-N 3.34Å; E212-E214 PolarHBondContact O-N 3.17Å
215L95.7Very high97Very high104 Ų10444.4 Ų44.455%0.54525%0.245SC..Hα-helixtrans-77.8-28.1-177-68.7174.4000113.2K211 E212 A213 L279K211-L215 HydrophobicContact CD-CD1 4.43Å; K211-L215 HydrophobicContact CD-CG 4.34Å; K211-L215 HydrophobicContact CG-CD1 4.35Å; K211-L215 VanDerWaalsContact O-CG 3.31Å; K211-L215 WeakPolarHBondContact O-CG 3.28Å; K211-L215 PolarHBondContact O-N 3.49Å; K211-L215 VanDerWaalsContact O-N 3.13Å; E212-L215 PolarHBondContact O-N 2.92Å; A213-L215 VanDerWaalsContact C-N 3.33Å; A213-L215 PolarHBondContact O-N 2.85Å; L215-L279 HydrophobicContact CD1-CD1 4.04Å
216R94.5Very high97Very high101 Ų10144.2 Ų44.238%0.38124%0.244SC..Hα-helixtrans-126.62.8-166.9-57.4-175.9177.399.515.8114.2E212 A213 S218 L279E212-R216 WeakPolarHBondContact O-CB 3.3Å; E212-R216 PolarHBondContact O-N 3.01Å; E212-R216 IonicContact OE1-CZ 3.55Å; E212-R216 IonicContact OE1-NH1 2.93Å; E212-R216 PolarHBondContact OE1-NH1 3.01Å; A213-R216 PolarHBondContact O-N 3.06Å; R216-S218 PolarHBondContact O-N 2.86Å; R216-S218 VanDerWaalsContact O-N 3.14Å; R216-L279 PolarHBondContact NH1-O 3.08Å; R216-L279 VanDerWaalsContact NH1-O 3.11Å; R216-L279 PolarHBondContact NH2-O 2.84Å
217G94.8Very high97Very high73 Ų7341.8 Ų41.875%0.75323%0.232SC*.SBendtrans77.9-24-175.400000114.7A213A213-G217 CarbonylContact O-C 3.38Å; A213-G217 WeakPolarHBondContact O-CA 3.44Å; A213-G217 PolarHBondContact O-N 3.47Å
218S94.3Very high97Very high76 Ų7643.5 Ų43.553%0.53125%0.249SC..SBendtrans-157153173.760.40000111.5R216R216-S218 PolarHBondContact O-N 2.86Å; R216-S218 VanDerWaalsContact O-N 3.14Å
219P95.7Very high97Very high23 Ų2344.4 Ų44.415%0.14925%0.253CS..  trans-68.5143.3172.3-11.824.8000111.9L209 A213 M223 W224L209-P219 HydrophobicContact CD2-CB 4.37Å; L209-P219 HydrophobicContact CD2-CG 3.7Å; L209-P219 HydrophobicContact CG-CB 4Å; L209-P219 HydrophobicContact CG-CG 3.9Å; A213-P219 HydrophobicContact CB-CG 3.95Å; P219-M223 HydrophobicContact CB-CB 4.48Å; P219-M223 HydrophobicContact CB-CG 4.45Å; P219-W224 HydrophobicContact CG-CZ2 3.88Å
220S97Very high97.1Very high32 Ų3243.7 Ų43.722%0.22425%0.249CC..  trans-67155.9174.5650000111.5E212 A222 M223 W224E212-S220 WeakPolarHBondContact OE2-CB 3.3Å; E212-S220 PolarHBondContact OE2-N 2.89Å; E212-S220 PolarHBondContact OE2-OG 3.01Å; S220-A222 PolarHBondContact O-N 2.6Å; S220-M223 PolarHBondContact O-N 3.14Å; S220-M223 VanDerWaalsContact O-N 3.14Å; S220-M223 WeakPolarHBondContact OG-CB 3.46Å; S220-M223 PolarHBondContact OG-N 2.75Å; S220-W224 PolarHBondContact O-N 2.95Å
221L97.4Very high97.1Very high63 Ų6345.8 Ų45.833%0.3326%0.259SS..Hα-helixtrans-57.6-39.1174.5-178.859.6000111.5M223 W224 L225 L285 L287 A290L221-M223 PolarHBondContact O-N 3.16Å; L221-W224 PolarHBondContact O-N 2.65Å; L221-L225 HydrophobicContact CD1-CG 4.46Å; L221-L225 WeakPolarHBondContact O-CG 3.21Å; L221-L225 PolarHBondContact O-N 3.32Å; L221-L285 HydrophobicContact CD2-CD2 4.42Å; L221-L285 HydrophobicContact CD2-CG 4.47Å; L221-L285 HydrophobicContact CG-CD2 4.22Å; L221-L287 HydrophobicContact CD2-CD2 3.99Å; L221-A290 HydrophobicContact CD2-CB 3.62Å; L221-A290 HydrophobicContact CG-CB 4.31Å
222A97.8Very high97.2Very high1 Ų147.6 Ų47.61%0.00827%0.27CS..Hα-helixtrans-60.3-44176.900000112.1S220 L225 V226 L278 L285 P364S220-A222 PolarHBondContact O-N 2.6Å; A222-L225 PolarHBondContact O-N 2.82Å; A222-V226 WeakPolarHBondContact O-CG2 3.4Å; A222-V226 PolarHBondContact O-N 3.23Å; A222-L278 HydrophobicContact CB-CD1 3.9Å; A222-L278 HydrophobicContact CB-CD2 3.87Å; A222-L285 HydrophobicContact CB-CB 4.43Å; A222-L285 HydrophobicContact CB-CD2 4.13Å; A222-P364 HydrophobicContact CB-CB 3.9Å; A222-P364 WeakPolarHBondContact CB-O 3.26Å
223M97.9Very high97.2Very high0 Ų049.4 Ų49.40%028%0.277CS..Hα-helixtrans-63.8-42.7177.6-173.96776.700111.9L209 E212 P219 S220 L221 L225 V226 N227 A275 L278 L279L209-M223 HydrophobicContact CB-CG 4.1Å; L209-M223 HydrophobicContact CD1-CG 4.31Å; L209-M223 HydrophobicContact CG-CG 4.15Å; E212-M223 HydrophobicContact CB-CE 4.07Å; E212-M223 WeakPolarHBondContact OE2-CB 3.45Å; E212-M223 WeakPolarHBondContact OE2-CG 3.32Å; P219-M223 HydrophobicContact CB-CB 4.48Å; P219-M223 HydrophobicContact CB-CG 4.45Å; S220-M223 PolarHBondContact O-N 3.14Å; S220-M223 VanDerWaalsContact O-N 3.14Å; S220-M223 WeakPolarHBondContact OG-CB 3.46Å; S220-M223 PolarHBondContact OG-N 2.75Å; L221-M223 PolarHBondContact O-N 3.16Å; M223-L225 PolarHBondContact O-N 2.99Å; M223-V226 PolarHBondContact O-N 2.74Å; M223-N227 WeakPolarHBondContact O-CB 3.49Å; M223-N227 PolarHBondContact O-N 2.94Å; M223-N227 PolarHBondContact O-ND2 2.84Å; M223-N227 PolarHBondContact SD-ND2 2.88Å; M223-N227 VanDerWaalsContact SD-ND2 3.37Å; M223-A275 WeakPolarHBondContact CE-O 3.27Å; M223-A275 HydrophobicContact SD-CB 3.86Å; M223-L278 HydrophobicContact CE-CB 3.7Å; M223-L279 HydrophobicContact CE-CB 4.4Å
224W97.8Very high97.3Very high139 Ų13948.1 Ų48.153%0.52727%0.266SS..Hα-helixtrans-58.9-45.3174.5-82.5116000112.5L209 P219 S220 L221 G228L209-W224 HydrophobicContact CD1-CD2 4.09Å; L209-W224 HydrophobicContact CD1-CE3 3.73Å; L209-W224 HydrophobicContact CD1-CH2 4.23Å; L209-W224 HydrophobicContact CD1-CZ3 3.81Å; L209-W224 HydrophobicContact CD2-CH2 4.17Å; L209-W224 HydrophobicContact CD2-CZ2 4.39Å; P219-W224 HydrophobicContact CG-CZ2 3.88Å; S220-W224 PolarHBondContact O-N 2.95Å; L221-W224 PolarHBondContact O-N 2.65Å; W224-G228 PolarHBondContact O-N 3.18Å
225L98.4Very high97.4Very high21 Ų2143.6 Ų43.611%0.1125%0.248CC..Hα-helixtrans-63.1-49.6179-68.8-176000111.9L221 A222 M223 N227 G228 F229 L285 A290 C294 P364L221-L225 HydrophobicContact CD1-CG 4.46Å; L221-L225 WeakPolarHBondContact O-CG 3.21Å; L221-L225 PolarHBondContact O-N 3.32Å; A222-L225 PolarHBondContact O-N 2.82Å; M223-L225 PolarHBondContact O-N 2.99Å; L225-N227 PolarHBondContact O-N 3.21Å; L225-G228 PolarHBondContact O-N 3.46Å; L225-F229 HydrophobicContact CB-CD2 4.43Å; L225-F229 HydrophobicContact CB-CE2 3.88Å; L225-F229 HydrophobicContact CB-CZ 4.06Å; L225-F229 HydrophobicContact CD1-CZ 4.5Å; L225-F229 HydrophobicContact CD2-CE1 4.29Å; L225-F229 HydrophobicContact CD2-CZ 3.92Å; L225-F229 HydrophobicContact CG-CZ 4.37Å; L225-F229 WeakPolarHBondContact O-CB 3.29Å; L225-F229 VanDerWaalsContact O-CD2 3.24Å; L225-F229 WeakPolarHBondContact O-CD2 3.43Å; L225-F229 WeakPolarHBondContact O-CG 3.4Å; L225-F229 PolarHBondContact O-N 3.29Å; L225-L285 HydrophobicContact CD1-CD2 3.62Å; L225-A290 HydrophobicContact CD1-CB 3.96Å; L225-C294 VanDerWaalsContact CD2-SG 3.57Å; L225-P364 HydrophobicContact CB-CG 4.2Å
226V98.5Very high97.4Very high0 Ų039.2 Ų39.20%023%0.225CC..Hα-helixtrans-57.4-50.3178.5171.70000110.7A222 M223 G228 Q230 Q274 A275 L278 P364A222-V226 WeakPolarHBondContact O-CG2 3.4Å; A222-V226 PolarHBondContact O-N 3.23Å; M223-V226 PolarHBondContact O-N 2.74Å; V226-G228 PolarHBondContact O-N 3.44Å; V226-Q230 WeakPolarHBondContact O-CB 3.25Å; V226-Q230 VanDerWaalsContact O-CG 3.25Å; V226-Q230 WeakPolarHBondContact O-CG 3.2Å; V226-Q230 PolarHBondContact O-N 3.34Å; V226-Q230 VanDerWaalsContact O-N 3.08Å; V226-Q274 HydrophobicContact CG1-CB 3.76Å; V226-Q274 HydrophobicContact CG2-CB 4.13Å; V226-A275 HydrophobicContact CG1-CB 4.25Å; V226-L278 HydrophobicContact CB-CD1 4.45Å; V226-L278 HydrophobicContact CG2-CD1 3.79Å; V226-P364 HydrophobicContact CG2-CB 3.83Å; V226-P364 HydrophobicContact CG2-CG 3.95Å
227N98.6Very high97.5Very high16 Ų1635.4 Ų35.49%0.08622%0.216CC..Hα-helixtrans-62.2-44.3180-83.2-104.9000111.7N205 L209 M223 L225 L231N205-N227 WeakPolarHBondContact CB-OD1 3.45Å; N205-N227 PolarHBondContact O-OD1 3.21Å; L209-N227 HydrophobicContact CD1-CB 3.87Å; M223-N227 WeakPolarHBondContact O-CB 3.49Å; M223-N227 PolarHBondContact O-N 2.94Å; M223-N227 PolarHBondContact O-ND2 2.84Å; M223-N227 PolarHBondContact SD-ND2 2.88Å; M223-N227 VanDerWaalsContact SD-ND2 3.37Å; L225-N227 PolarHBondContact O-N 3.21Å; N227-L231 WeakPolarHBondContact O-CB 3.42Å; N227-L231 PolarHBondContact O-N 2.78Å
228G98.6Very high97.5Very high36 Ų3632 Ų3237%0.37118%0.18SC..Hα-helixtrans-65.6-45.2-179.300000113W224 L225 V226 L232W224-G228 PolarHBondContact O-N 3.18Å; L225-G228 PolarHBondContact O-N 3.46Å; V226-G228 PolarHBondContact O-N 3.44Å; G228-L232 WeakPolarHBondContact O-CB 3.46Å; G228-L232 PolarHBondContact O-N 2.9Å
229F98.6Very high97.6Very high20 Ų2036.4 Ų36.49%0.08819%0.185CC..Hα-helixtrans-65.1-44.6178.7-60.5-25.5000112L225 L232 Y233 I293 N297 W361L225-F229 HydrophobicContact CB-CD2 4.43Å; L225-F229 HydrophobicContact CB-CE2 3.88Å; L225-F229 HydrophobicContact CB-CZ 4.06Å; L225-F229 HydrophobicContact CD1-CZ 4.5Å; L225-F229 HydrophobicContact CD2-CE1 4.29Å; L225-F229 HydrophobicContact CD2-CZ 3.92Å; L225-F229 HydrophobicContact CG-CZ 4.37Å; L225-F229 WeakPolarHBondContact O-CB 3.29Å; L225-F229 VanDerWaalsContact O-CD2 3.24Å; L225-F229 WeakPolarHBondContact O-CD2 3.43Å; L225-F229 WeakPolarHBondContact O-CG 3.4Å; L225-F229 PolarHBondContact O-N 3.29Å; F229-L232 WeakPolarHBondContact O-CB 3.27Å; F229-L232 PolarHBondContact O-N 3.05Å; F229-Y233 PolarHBondContact O-N 2.89Å; F229-I293 HydrophobicContact CE2-CG2 3.7Å; F229-I293 HydrophobicContact CZ-CG2 4.13Å; F229-N297 HydrophobicContact CD1-CB 4.17Å; F229-N297 WeakPolarHBondContact CD1-ND2 3.49Å; F229-N297 HydrophobicContact CD2-CB 4.39Å; F229-N297 HydrophobicContact CE1-CB 4Å; F229-N297 HydrophobicContact CE2-CB 4.23Å; F229-N297 HydrophobicContact CG-CB 4.37Å; F229-N297 HydrophobicContact CZ-CB 4.03Å; F229-W361 VanDerWaalsContact CB-CD1 3.5Å; F229-W361 HydrophobicContact CB-CG 4.46Å; F229-W361 AromaticContact CD2-CD1 3.91Å
230Q98.6Very high97.4Very high0 Ų038.1 Ų38.10%019%0.191CC..Hα-helixtrans-70.2-36.7-179.6-66.4-177.1-11.200111.5W201 N205 V226 Y233 V234 Y271 W361W201-Q230 HydrophobicContact CH2-CB 4.02Å; W201-Q230 HydrophobicContact CH2-CG 4.1Å; W201-Q230 HydrophobicContact CZ2-CB 3.51Å; W201-Q230 HydrophobicContact CZ2-CG 3.43Å; W201-Q230 VanDerWaalsContact CZ2-CG 3.43Å; W201-Q230 VanDerWaalsContact NE1-OE1 3.11Å; N205-Q230 PolarHBondContact ND2-OE1 3.24Å; V226-Q230 WeakPolarHBondContact O-CB 3.25Å; V226-Q230 VanDerWaalsContact O-CG 3.25Å; V226-Q230 WeakPolarHBondContact O-CG 3.2Å; V226-Q230 PolarHBondContact O-N 3.34Å; V226-Q230 VanDerWaalsContact O-N 3.08Å; Q230-Y233 PolarHBondContact O-N 3.5Å; Q230-V234 WeakPolarHBondContact O-CG2 3.26Å; Q230-V234 PolarHBondContact O-N 3.46Å; Q230-Y271 PolarHBondContact NE2-O 3.29Å; Q230-Y271 VanDerWaalsContact NE2-O 3.11Å; Q230-Y271 PolarHBondContact OE1-O 3.21Å; Q230-W361 HydrophobicContact CG-CD2 3.98Å; Q230-W361 HydrophobicContact CG-CE3 4.03Å; Q230-W361 HydrophobicContact CG-CG 4.28Å
231L98.5Very high97.2Very high83 Ų8336.7 Ų36.744%0.43518%0.181SC..Hα-helixtrans-62.7-43.3171.5175.562.1000111.9L106 V202 N227 Y233 V234 G235L106-L231 HydrophobicContact CD2-CD1 4.47Å; V202-L231 HydrophobicContact CG1-CD1 3.72Å; V202-L231 HydrophobicContact CG2-CD1 4.18Å; N227-L231 WeakPolarHBondContact O-CB 3.42Å; N227-L231 PolarHBondContact O-N 2.78Å; L231-Y233 VanDerWaalsContact C-N 3.31Å; L231-Y233 PolarHBondContact O-N 2.92Å; L231-V234 PolarHBondContact O-N 2.82Å; L231-G235 PolarHBondContact O-N 2.85Å
232L98.2Very high96.9Very high78 Ų7836.3 Ų36.341%0.40818%0.177SC..Hα-helixtrans-58.6-45.9176.1176.765.4000110.7G228 F229 G235 D236 Y301G228-L232 WeakPolarHBondContact O-CB 3.46Å; G228-L232 PolarHBondContact O-N 2.9Å; F229-L232 WeakPolarHBondContact O-CB 3.27Å; F229-L232 PolarHBondContact O-N 3.05Å; L232-G235 PolarHBondContact O-N 2.8Å; L232-D236 WeakPolarHBondContact O-CB 3.44Å; L232-D236 PolarHBondContact O-N 2.98Å; L232-Y301 HydrophobicContact CD2-CD2 4.39Å; L232-Y301 HydrophobicContact CD2-CG 4.48Å; L232-Y301 HydrophobicContact CG-CE2 4.46Å
233Y98Very high96.5Very high38 Ų3837.6 Ų37.615%0.14919%0.188CC..Hα-helixtrans-61.4-48.8178.8-177.1-89.8000112.3W201 F229 Q230 L231 D236 A237 F304 D354 M357 W361W201-Y233 HydrophobicContact CH2-CD1 4.16Å; W201-Y233 AromaticContact CZ3-CD1 3.92Å; W201-Y233 HydrophobicContact CZ3-CD1 3.92Å; W201-Y233 HydrophobicContact CZ3-CE1 4.4Å; F229-Y233 PolarHBondContact O-N 2.89Å; Q230-Y233 PolarHBondContact O-N 3.5Å; L231-Y233 VanDerWaalsContact C-N 3.31Å; L231-Y233 PolarHBondContact O-N 2.92Å; Y233-D236 PolarHBondContact O-N 3.22Å; Y233-A237 PolarHBondContact O-N 3.44Å; Y233-F304 HydrophobicContact CE2-CZ 4.38Å; Y233-D354 WeakPolarHBondContact CE2-OD1 3.24Å; Y233-M357 HydrophobicContact CD2-CE 3.86Å; Y233-M357 HydrophobicContact CD2-SD 4.32Å; Y233-M357 HydrophobicContact CE2-CE 3.92Å; Y233-W361 AromaticContact CD1-CH2 3.91Å; Y233-W361 HydrophobicContact CD1-CH2 3.91Å; Y233-W361 HydrophobicContact CD1-CZ2 4.46Å; Y233-W361 AromaticContact CD2-CH2 3.72Å; Y233-W361 HydrophobicContact CD2-CH2 3.72Å; Y233-W361 AromaticContact CD2-CZ2 3.68Å; Y233-W361 HydrophobicContact CD2-CZ2 3.68Å; Y233-W361 HydrophobicContact CE1-CH2 4.33Å; Y233-W361 HydrophobicContact CE2-CH2 4.15Å; Y233-W361 HydrophobicContact CE2-CZ2 4.44Å; Y233-W361 AromaticContact CG-CH2 3.58Å; Y233-W361 HydrophobicContact CG-CH2 3.58Å; Y233-W361 AromaticContact CG-CZ2 3.7Å; Y233-W361 HydrophobicContact CG-CZ2 3.7Å
234V98.1Very high96.2Very high0 Ų038.7 Ų38.70%019%0.194CC..Hα-helixtrans-65.5-43.6178.21720000111.6L198 W201 V202 Q230 L231 D236 A237 L238L198-V234 HydrophobicContact CB-CG1 3.98Å; L198-V234 HydrophobicContact CB-CG2 4.38Å; L198-V234 HydrophobicContact CD2-CG2 4.42Å; W201-V234 HydrophobicContact CD2-CG2 4.17Å; W201-V234 HydrophobicContact CE3-CG2 3.24Å; W201-V234 HydrophobicContact CH2-CG2 4.34Å; W201-V234 HydrophobicContact CZ3-CG2 3.34Å; V202-V234 HydrophobicContact CG2-CB 3.71Å; V202-V234 HydrophobicContact CG2-CG1 3.66Å; V202-V234 HydrophobicContact CG2-CG2 3.84Å; Q230-V234 WeakPolarHBondContact O-CG2 3.26Å; Q230-V234 PolarHBondContact O-N 3.46Å; L231-V234 PolarHBondContact O-N 2.82Å; V234-D236 VanDerWaalsContact C-N 3.31Å; V234-D236 PolarHBondContact O-N 3.04Å; V234-A237 PolarHBondContact O-N 3.45Å; V234-L238 HydrophobicContact CG1-CD1 3.77Å; V234-L238 HydrophobicContact CG1-CG 4.34Å; V234-L238 WeakPolarHBondContact O-CB 3.27Å; V234-L238 WeakPolarHBondContact O-CG 3.34Å; V234-L238 PolarHBondContact O-N 3.43Å
235G97.8Very high95.9Very high11 Ų1132.2 Ų32.211%0.11317%0.169CC..Hα-helixtrans-60-42.9176.900000111.8L231 L232 L238 W239L231-G235 PolarHBondContact O-N 2.85Å; L232-G235 PolarHBondContact O-N 2.8Å; G235-L238 PolarHBondContact O-N 3.04Å; G235-W239 VanDerWaalsContact O-CB 3.26Å; G235-W239 WeakPolarHBondContact O-CB 3.47Å; G235-W239 PolarHBondContact O-N 3.09Å
236D96.8Very high95.4Very high12 Ų1233.3 Ų33.36%0.06418%0.177CC..Hα-helixtrans-65.2-40.5177.1176.378.9000112.6L232 Y233 V234 W239 H240 Y301 R305L232-D236 WeakPolarHBondContact O-CB 3.44Å; L232-D236 PolarHBondContact O-N 2.98Å; Y233-D236 PolarHBondContact O-N 3.22Å; V234-D236 VanDerWaalsContact C-N 3.31Å; V234-D236 PolarHBondContact O-N 3.04Å; D236-W239 PolarHBondContact O-N 3.33Å; D236-H240 WeakPolarHBondContact O-CB 3.32Å; D236-H240 PolarHBondContact O-N 3.07Å; D236-H240 PolarHBondContact O-ND1 3.16Å; D236-H240 IonicContact OD1-CE1 3.81Å; D236-H240 IonicContact OD1-ND1 3.23Å; D236-H240 PolarHBondContact OD1-ND1 2.82Å; D236-Y301 HydrophobicContact CB-CE2 4.11Å; D236-Y301 PolarHBondContact OD1-OH 3.39Å; D236-R305 IonicContact OD1-CZ 3.56Å; D236-R305 VanDerWaalsContact OD1-CZ 3.28Å; D236-R305 IonicContact OD1-NE 3.34Å; D236-R305 PolarHBondContact OD1-NE 3.44Å; D236-R305 IonicContact OD1-NH2 2.99Å; D236-R305 PolarHBondContact OD1-NH2 3.16Å; D236-R305 VanDerWaalsContact OD1-NH2 3.12Å; D236-R305 IonicContact OD2-CZ 3.93Å; D236-R305 IonicContact OD2-NE 3.6Å; D236-R305 PolarHBondContact OD2-NE 3.17Å; D236-R305 IonicContact OD2-NH2 2.93Å; D236-R305 PolarHBondContact OD2-NH2 2.91Å
237A95.3Very high94.9Very high22 Ų2234.9 Ų34.918%0.18219%0.187CC..Hα-helixtrans-63.2-45.4174.100000112Y233 V234 H240 E241Y233-A237 PolarHBondContact O-N 3.44Å; V234-A237 PolarHBondContact O-N 3.45Å; A237-H240 CarbonylContact O-C 3.55Å; A237-H240 VanDerWaalsContact O-C 3.3Å; A237-H240 PolarHBondContact O-N 3.41Å; A237-E241 WeakPolarHBondContact O-CA 3.09Å; A237-E241 PolarHBondContact O-N 2.86Å
238L96Very high94.4Very high2 Ų234.8 Ų34.81%0.0119%0.186CC..Hα-helixtrans-72.8-28.8179.1-67.5172.4000113F103 L106 L194 I199 V234 G235 E241F103-L238 HydrophobicContact CB-CB 4.33Å; F103-L238 HydrophobicContact CD2-CB 4.49Å; L106-L238 HydrophobicContact CB-CD1 3.81Å; L106-L238 HydrophobicContact CD2-CD1 4Å; L106-L238 HydrophobicContact CG-CD1 4.37Å; L194-L238 HydrophobicContact CB-CD2 4.25Å; L194-L238 HydrophobicContact CD2-CD2 3.85Å; I199-L238 HydrophobicContact CD1-CD1 4.26Å; I199-L238 HydrophobicContact CG1-CD1 3.85Å; V234-L238 HydrophobicContact CG1-CD1 3.77Å; V234-L238 HydrophobicContact CG1-CG 4.34Å; V234-L238 WeakPolarHBondContact O-CB 3.27Å; V234-L238 WeakPolarHBondContact O-CG 3.34Å; V234-L238 PolarHBondContact O-N 3.43Å; G235-L238 PolarHBondContact O-N 3.04Å; L238-E241 VanDerWaalsContact O-CB 3.29Å; L238-E241 WeakPolarHBondContact O-CB 3.14Å
239W94.9Very high93.9Very high167 Ų16734.1 Ų34.163%0.63317%0.174SC*.Hα-helixtrans-69.7-38.3172.7-170.5-89.9000111.6F103 G235 D236 E241F103-W239 HydrophobicContact CB-CE3 4.34Å; F103-W239 AromaticContact CD1-CE3 3.6Å; F103-W239 HydrophobicContact CD1-CE3 3.6Å; F103-W239 AromaticContact CD1-CZ3 3.67Å; F103-W239 HydrophobicContact CD1-CZ3 3.67Å; F103-W239 HydrophobicContact CD2-CB 4.25Å; F103-W239 AromaticContact CD2-CE3 3.79Å; F103-W239 HydrophobicContact CD2-CE3 3.79Å; F103-W239 AromaticContact CE1-CE3 3.73Å; F103-W239 HydrophobicContact CE1-CE3 3.73Å; F103-W239 AromaticContact CE1-CZ3 3.6Å; F103-W239 HydrophobicContact CE1-CZ3 3.6Å; F103-W239 AromaticContact CE2-CE3 3.9Å; F103-W239 HydrophobicContact CE2-CE3 3.9Å; F103-W239 AromaticContact CG-CE3 3.63Å; F103-W239 HydrophobicContact CG-CE3 3.63Å; F103-W239 HydrophobicContact CG-CZ3 4.19Å; F103-W239 AromaticContact CZ-CE3 3.87Å; F103-W239 HydrophobicContact CZ-CE3 3.87Å; F103-W239 HydrophobicContact CZ-CZ3 4.07Å; G235-W239 VanDerWaalsContact O-CB 3.26Å; G235-W239 WeakPolarHBondContact O-CB 3.47Å; G235-W239 PolarHBondContact O-N 3.09Å; D236-W239 PolarHBondContact O-N 3.33Å; W239-E241 VanDerWaalsContact C-N 3.33Å
240H93.1Very high93.6Very high60 Ų6033.3 Ų33.328%0.27817%0.17SC..THydrogen-bonded Turntrans-98.829.1177.2-60.491.5000112.8D236 A237 E242 A243 R305D236-H240 WeakPolarHBondContact O-CB 3.32Å; D236-H240 PolarHBondContact O-N 3.07Å; D236-H240 PolarHBondContact O-ND1 3.16Å; D236-H240 IonicContact OD1-CE1 3.81Å; D236-H240 IonicContact OD1-ND1 3.23Å; D236-H240 PolarHBondContact OD1-ND1 2.82Å; A237-H240 CarbonylContact O-C 3.55Å; A237-H240 VanDerWaalsContact O-C 3.3Å; A237-H240 PolarHBondContact O-N 3.41Å; H240-E242 PolarHBondContact O-N 3.33Å; H240-E242 VanDerWaalsContact O-N 3.07Å; H240-A243 VanDerWaalsContact O-CB 3.25Å; H240-A243 WeakPolarHBondContact O-CB 2.97Å; H240-A243 PolarHBondContact O-N 3.32Å; H240-R305 PolarHBondContact CD2-NH1 2.8Å; H240-R305 PolarHBondContact CE1-NH1 2.89Å; H240-R305 PolarHBondContact ND1-NH1 3.46Å; H240-R305 PolarHBondContact ND1-NH2 3.14Å; H240-R305 PolarHBondContact NE2-NH1 3.24Å
241E93.3Very high93.1Very high2 Ų234.9 Ų34.91%0.00918%0.18CC..G310 helixtrans-49.8-38.1-175.4164.6174.7-148.300113.3I100 N101 G102 Y190 L194 R195 A237 L238 W239 A243 I244I100-E241 WeakPolarHBondContact CA-OE2 3.42Å; I100-E241 HydrophobicContact CD1-CG 4.13Å; I100-E241 HydrophobicContact CG2-CB 4.24Å; I100-E241 HydrophobicContact CG2-CG 4.14Å; I100-E241 WeakPolarHBondContact CG2-OE2 3.27Å; N101-E241 PolarHBondContact N-OE2 3.2Å; G102-E241 WeakPolarHBondContact CA-OE2 3.41Å; G102-E241 PolarHBondContact N-OE2 3.14Å; Y190-E241 HydrophobicContact CE2-CG 4.49Å; Y190-E241 WeakPolarHBondContact OH-CG 3.32Å; Y190-E241 PolarHBondContact OH-OE1 2.74Å; L194-E241 HydrophobicContact CD1-CG 3.73Å; R195-E241 IonicContact CZ-OE1 2.86Å; R195-E241 IonicContact NH1-OE1 3.95Å; R195-E241 PolarHBondContact NH1-OE1 2.86Å; R195-E241 IonicContact NH2-OE1 2.73Å; R195-E241 PolarHBondContact NH2-OE1 2.82Å; R195-E241 IonicContact NH2-OE2 2.74Å; A237-E241 WeakPolarHBondContact O-CA 3.09Å; A237-E241 PolarHBondContact O-N 2.86Å; L238-E241 VanDerWaalsContact O-CB 3.29Å; L238-E241 WeakPolarHBondContact O-CB 3.14Å; W239-E241 VanDerWaalsContact C-N 3.33Å; E241-A243 PolarHBondContact O-N 3.13Å; E241-A243 VanDerWaalsContact O-N 3.11Å; E241-I244 WeakPolarHBondContact O-CB 3.27Å; E241-I244 PolarHBondContact O-N 3.2Å
242E91.2Very high92.5Very high54 Ų5434.9 Ų34.925%0.25218%0.178SC..G310 helixtrans-58.1-28178.3-166.4-173.1130.200113.2K83 A85 H240 I244 L245 K316K83-E242 IonicContact NZ-OE2 3.15Å; K83-E242 PolarHBondContact NZ-OE2 3.46Å; A85-E242 HydrophobicContact CB-CG 3.86Å; H240-E242 PolarHBondContact O-N 3.33Å; H240-E242 VanDerWaalsContact O-N 3.07Å; E242-I244 PolarHBondContact O-N 3.05Å; E242-L245 PolarHBondContact O-N 3.26Å; E242-K316 VanDerWaalsContact OE1-CE 3.3Å; E242-K316 WeakPolarHBondContact OE1-CE 3.19Å; E242-K316 IonicContact OE1-NZ 2.97Å; E242-K316 PolarHBondContact OE1-NZ 2.62Å; E242-K316 IonicContact OE2-NZ 3.79Å
243A89.3Confident92.2Very high28 Ų2831.8 Ų31.823%0.23116%0.162CC..G310 helixtrans-68-24.5178.500000112.7H240 E241 L245 T246H240-A243 VanDerWaalsContact O-CB 3.25Å; H240-A243 WeakPolarHBondContact O-CB 2.97Å; H240-A243 PolarHBondContact O-N 3.32Å; E241-A243 PolarHBondContact O-N 3.13Å; E241-A243 VanDerWaalsContact O-N 3.11Å; A243-L245 VanDerWaalsContact C-N 3.25Å; A243-L245 PolarHBondContact O-N 3.39Å; A243-T246 PolarHBondContact O-N 2.98Å; A243-T246 PolarHBondContact O-OG1 3.43Å
244I90.4Very high92Very high23 Ų2330.2 Ų30.212%0.11816%0.156CC..G310 helixtrans-68.6-27.7-179.1-66.2168.3000111.2L194 E241 E242 T246 T247 I250L194-I244 HydrophobicContact CD1-CD1 3.77Å; L194-I244 HydrophobicContact CD2-CD1 3.16Å; L194-I244 HydrophobicContact CG-CD1 3.77Å; E241-I244 WeakPolarHBondContact O-CB 3.27Å; E241-I244 PolarHBondContact O-N 3.2Å; E242-I244 PolarHBondContact O-N 3.05Å; I244-T246 PolarHBondContact O-N 3.5Å; I244-T247 HydrophobicContact CB-CG2 4.49Å; I244-T247 HydrophobicContact CG2-CG2 4.41Å; I244-T247 WeakPolarHBondContact O-CB 3.48Å; I244-T247 WeakPolarHBondContact O-CG2 3.48Å; I244-T247 PolarHBondContact O-N 3.08Å; I244-T247 PolarHBondContact O-OG1 2.61Å; I244-I250 HydrophobicContact CG2-CG1 4.15Å; I244-I250 WeakPolarHBondContact O-CG1 3.34Å
245L91.6Very high91.9Very high3 Ų330.3 Ų30.32%0.01616%0.157CC..G310 helixtrans-62.3-4.6174.8-57.7-179.8000114.2A85 Y98 I100 Y190 E242 A243A85-L245 HydrophobicContact CB-CD1 4.05Å; Y98-L245 HydrophobicContact CD1-CD2 3.68Å; Y98-L245 HydrophobicContact CD2-CD1 3.92Å; Y98-L245 HydrophobicContact CD2-CD2 3.6Å; Y98-L245 HydrophobicContact CD2-CG 4.39Å; Y98-L245 HydrophobicContact CE1-CD2 3.93Å; Y98-L245 HydrophobicContact CE2-CD2 3.89Å; Y98-L245 HydrophobicContact CG-CD1 4.15Å; Y98-L245 HydrophobicContact CG-CD2 3.48Å; Y98-L245 VanDerWaalsContact CG-CD2 3.48Å; Y98-L245 HydrophobicContact CG-CG 4.48Å; I100-L245 HydrophobicContact CD1-CD1 4.36Å; Y190-L245 HydrophobicContact CD2-CD2 3.72Å; Y190-L245 HydrophobicContact CE2-CD2 3.45Å; Y190-L245 VanDerWaalsContact CE2-CD2 3.45Å; Y190-L245 HydrophobicContact CE2-CG 4.33Å; E242-L245 PolarHBondContact O-N 3.26Å; A243-L245 VanDerWaalsContact C-N 3.25Å; A243-L245 PolarHBondContact O-N 3.39Å
246T88.2Confident91.9Very high45 Ų4529.9 Ų29.928%0.27615%0.153SC..G310 helixtrans-114.76177.472.90000113.6A243 I244A243-T246 PolarHBondContact O-N 2.98Å; A243-T246 PolarHBondContact O-OG1 3.43Å; I244-T246 PolarHBondContact O-N 3.5Å
247T88.8Confident91.9Very high33 Ų3329.3 Ų29.320%0.20215%0.15CC..SBendtrans-77.9156.1177.964.40000110.9I244 D249 I250 T251I244-T247 HydrophobicContact CB-CG2 4.49Å; I244-T247 HydrophobicContact CG2-CG2 4.41Å; I244-T247 WeakPolarHBondContact O-CB 3.48Å; I244-T247 WeakPolarHBondContact O-CG2 3.48Å; I244-T247 PolarHBondContact O-N 3.08Å; I244-T247 PolarHBondContact O-OG1 2.61Å; T247-D249 PolarHBondContact O-N 3.44Å; T247-I250 PolarHBondContact O-N 3.18Å; T247-T251 PolarHBondContact O-N 2.81Å; T247-T251 PolarHBondContact O-OG1 2.93Å; T247-T251 VanDerWaalsContact O-OG1 3.1Å
248M87.1Confident92Very high13 Ų1329.6 Ų29.66%0.06415%0.147CC..Hα-helixtrans-56.1-37.4175.7-173.5179.4-68.900112I250 T251 H252 D253 R389 D390M248-I250 VanDerWaalsContact C-N 3.34Å; M248-I250 PolarHBondContact O-N 3.38Å; M248-T251 PolarHBondContact O-N 3.37Å; M248-H252 HydrophobicContact CG-CB 4.17Å; M248-H252 PolarHBondContact O-N 3.45Å; M248-D253 PolarHBondContact O-N 2.95Å; M248-D253 VanDerWaalsContact O-N 3.07Å; M248-R389 HydrophobicContact CE-CB 4.12Å; M248-R389 HydrophobicContact SD-CB 4.22Å; M248-R389 VanDerWaalsContact SD-CZ 3.56Å; M248-R389 PolarHBondContact SD-NH1 3.36Å; M248-D390 HydrophobicContact CE-CB 3.86Å
249D88.9Confident92Very high22 Ų2230.2 Ų30.212%0.11815%0.151CC..Hα-helixtrans-62-42.6-178.7-50.3-47.9000110.7K189 T247 L259 R386K189-D249 VanDerWaalsContact CD-O 3.27Å; K189-D249 WeakPolarHBondContact CD-O 3.41Å; K189-D249 WeakPolarHBondContact CE-O 3.32Å; K189-D249 PolarHBondContact NZ-O 2.88Å; T247-D249 PolarHBondContact O-N 3.44Å; D249-L259 HydrophobicContact CB-CD1 4.41Å; D249-R386 IonicContact OD1-CZ 3.42Å; D249-R386 IonicContact OD1-NH1 3.51Å; D249-R386 PolarHBondContact OD1-NH1 3.29Å; D249-R386 IonicContact OD1-NH2 2.63Å; D249-R386 IonicContact OD2-CZ 3.28Å; D249-R386 VanDerWaalsContact OD2-CZ 3.28Å; D249-R386 IonicContact OD2-NH1 3.47Å; D249-R386 PolarHBondContact OD2-NH1 3.45Å; D249-R386 IonicContact OD2-NH2 3.12Å; D249-R386 PolarHBondContact OD2-NH2 3.14Å
250I90.9Very high92.1Very high4 Ų422.3 Ų22.32%0.02112%0.121CC..Hα-helixtrans-75-45.5175.8-65.1-61.1000112.6N180 K189 Y190 E193 I244 T247 M248N180-I250 PolarHBondContact OD1-O 2.93Å; K189-I250 HydrophobicContact CD-CD1 3.72Å; K189-I250 HydrophobicContact CG-CD1 4.11Å; K189-I250 PolarHBondContact NZ-O 3.27Å; Y190-I250 HydrophobicContact CD2-CD1 4.21Å; E193-I250 WeakPolarHBondContact OE2-CD1 3.26Å; E193-I250 WeakPolarHBondContact OE2-CG1 3.08Å; I244-I250 HydrophobicContact CG2-CG1 4.15Å; I244-I250 WeakPolarHBondContact O-CG1 3.34Å; T247-I250 PolarHBondContact O-N 3.18Å; M248-I250 VanDerWaalsContact C-N 3.34Å; M248-I250 PolarHBondContact O-N 3.38Å
251T89.6Confident92.4Very high33 Ų3319.5 Ų19.520%0.20211%0.108CC..Hα-helixtrans-92.1-20.6-165.265.60000114.9Q88 T247 M248Q88-T251 HydrophobicContact CB-CG2 4.15Å; Q88-T251 HydrophobicContact CG-CG2 3.77Å; T247-T251 PolarHBondContact O-N 2.81Å; T247-T251 PolarHBondContact O-OG1 2.93Å; T247-T251 VanDerWaalsContact O-OG1 3.1Å; M248-T251 PolarHBondContact O-N 3.37Å
252H86.1Confident92.6Very high83 Ų8320.3 Ų20.338%0.38412%0.116SC..THydrogen-bonded Turntrans-128.6-41.8-172-70.4-57.8000113.8M248M248-H252 HydrophobicContact CG-CB 4.17Å; M248-H252 PolarHBondContact O-N 3.45Å
253D90.7Very high92.9Very high13 Ų1318.7 Ų18.77%0.0711%0.109CC..SBendtrans-81.4140.6-173.2-68.7-10.4000111.1L179 K189 M248 L259 R389L179-D253 WeakPolarHBondContact CD1-O 3.32Å; K189-D253 WeakPolarHBondContact CE-O 3.28Å; K189-D253 PolarHBondContact NZ-O 3.21Å; M248-D253 PolarHBondContact O-N 2.95Å; M248-D253 VanDerWaalsContact O-N 3.07Å; D253-L259 HydrophobicContact CB-CD1 4.26Å; D253-R389 IonicContact OD1-CZ 3.94Å; D253-R389 IonicContact OD1-NH1 3.74Å; D253-R389 IonicContact OD1-NH2 3.06Å; D253-R389 PolarHBondContact OD1-NH2 2.96Å; D253-R389 IonicContact OD2-CZ 2.72Å; D253-R389 IonicContact OD2-NH1 2.81Å; D253-R389 PolarHBondContact OD2-NH1 3.09Å; D253-R389 IonicContact OD2-NH2 2.77Å; D253-R389 PolarHBondContact OD2-NH2 3.11Å
254G93.9Very high93.2Very high4 Ų417.5 Ų17.54%0.04110%0.099CC..  trans-68.1164.1171.700000111.4L175 G176 L259L175-G254 CarbonylContact O-C 3.38Å; G176-G254 WeakPolarHBondContact O-CA 3.5Å; G254-L259 VanDerWaalsContact O-CD1 3.28Å; G254-L259 WeakPolarHBondContact O-CD1 3.38Å
255F96.5Very high93.6Very high3 Ų316.4 Ų16.41%0.0139%0.094CC..  trans-102.591.4173.3-165.5-124.6000111.2F144 L148 E178 P181 F188 K189 C192 L259 A260F144-F255 HydrophobicContact CD1-CE1 4.43Å; F144-F255 AromaticContact CE1-CE1 3.6Å; F144-F255 HydrophobicContact CE1-CE1 3.6Å; F144-F255 HydrophobicContact CE1-CZ 4.12Å; F144-F255 HydrophobicContact CZ-CE1 4.15Å; L148-F255 HydrophobicContact CD1-CD1 3.34Å; L148-F255 HydrophobicContact CD1-CE1 3.57Å; L148-F255 HydrophobicContact CD1-CG 4.27Å; L148-F255 HydrophobicContact CD2-CD1 4.31Å; L148-F255 HydrophobicContact CG-CD1 4.46Å; E178-F255 PolarHBondContact O-N 2.69Å; P181-F255 HydrophobicContact CG-CB 3.72Å; P181-F255 HydrophobicContact CG-CD1 3.73Å; P181-F255 HydrophobicContact CG-CG 4.18Å; F188-F255 HydrophobicContact CB-CD1 4.12Å; F188-F255 HydrophobicContact CB-CE1 3.84Å; K189-F255 HydrophobicContact CB-CB 3.99Å; K189-F255 HydrophobicContact CB-CD1 4.1Å; K189-F255 HydrophobicContact CB-CD2 3.71Å; K189-F255 HydrophobicContact CB-CE2 4.2Å; K189-F255 HydrophobicContact CB-CG 3.67Å; K189-F255 HydrophobicContact CG-CB 4.27Å; K189-F255 HydrophobicContact CG-CD2 3.59Å; K189-F255 HydrophobicContact CG-CE2 4.13Å; K189-F255 HydrophobicContact CG-CG 4.01Å; C192-F255 HydrophobicContact CB-CE2 4.25Å; C192-F255 HydrophobicContact CB-CZ 3.67Å; F255-L259 HydrophobicContact CD2-CB 3.6Å; F255-L259 HydrophobicContact CD2-CD1 4.14Å; F255-L259 HydrophobicContact CE2-CB 3.76Å; F255-A260 HydrophobicContact CE2-CB 4.33Å; F255-A260 HydrophobicContact CZ-CB 4.05Å
256G96.7Very high93.9Very high2 Ų216.8 Ų16.82%0.02110%0.095CC..SBendtrans-122-160.7176.700000112.2F174 L175 M258 L259 A260F174-G256 CarbonylContact O-C 3.57Å; L175-G256 PolarHBondContact O-N 3.42Å; G256-M258 VanDerWaalsContact C-N 3.27Å; G256-M258 PolarHBondContact O-N 3.35Å; G256-L259 PolarHBondContact O-N 3.44Å; G256-A260 VanDerWaalsContact O-CB 3.31Å; G256-A260 WeakPolarHBondContact O-CB 3.48Å; G256-A260 PolarHBondContact O-N 2.94Å
257F97.9Very high94.3Very high0 Ų015.5 Ų15.50%09%0.087CC..Hα-helixtrans-56.2-39.9-177.2178.9-88.5000113.6L23 P27 A141 F142 S145 F173 F174 L259 A260 F261L23-F257 HydrophobicContact CD2-CB 3.92Å; L23-F257 HydrophobicContact CD2-CD1 3.28Å; L23-F257 HydrophobicContact CD2-CD2 4.24Å; L23-F257 HydrophobicContact CD2-CE1 3.75Å; L23-F257 HydrophobicContact CD2-CG 3.54Å; L23-F257 HydrophobicContact CD2-CZ 4.41Å; P27-F257 HydrophobicContact CG-CZ 4.09Å; A141-F257 HydrophobicContact CB-CE2 4.29Å; F142-F257 AromaticContact CD1-CD2 3.79Å; F142-F257 HydrophobicContact CD1-CD2 3.79Å; F142-F257 AromaticContact CD1-CE2 3.54Å; F142-F257 HydrophobicContact CD1-CE2 3.54Å; F142-F257 HydrophobicContact CD1-CZ 4.44Å; F142-F257 AromaticContact CD2-CE2 3.71Å; F142-F257 HydrophobicContact CD2-CE2 3.71Å; F142-F257 HydrophobicContact CD2-CZ 4.38Å; F142-F257 AromaticContact CE1-CD2 3.87Å; F142-F257 HydrophobicContact CE1-CD2 3.87Å; F142-F257 AromaticContact CE1-CE2 3.41Å; F142-F257 HydrophobicContact CE1-CE2 3.41Å; F142-F257 VanDerWaalsContact CE1-CE2 3.41Å; F142-F257 AromaticContact CE1-CZ 3.88Å; F142-F257 HydrophobicContact CE1-CZ 3.88Å; F142-F257 AromaticContact CE2-CE2 3.58Å; F142-F257 HydrophobicContact CE2-CE2 3.58Å; F142-F257 AromaticContact CE2-CZ 3.81Å; F142-F257 HydrophobicContact CE2-CZ 3.81Å; F142-F257 HydrophobicContact CG-CD2 4.19Å; F142-F257 AromaticContact CG-CE2 3.68Å; F142-F257 HydrophobicContact CG-CE2 3.68Å; F142-F257 HydrophobicContact CZ-CD2 4.33Å; F142-F257 AromaticContact CZ-CE2 3.42Å; F142-F257 HydrophobicContact CZ-CE2 3.42Å; F142-F257 VanDerWaalsContact CZ-CE2 3.42Å; F142-F257 AromaticContact CZ-CZ 3.52Å; F142-F257 HydrophobicContact CZ-CZ 3.52Å; S145-F257 WeakPolarHBondContact OG-CA 3.5Å; S145-F257 PolarHBondContact OG-N 3.24Å; F173-F257 HydrophobicContact CD1-CB 4.11Å; F173-F257 HydrophobicContact CE1-CB 3.65Å; F173-F257 HydrophobicContact CE1-CD2 4.21Å; F173-F257 HydrophobicContact CE1-CG 4.11Å; F173-F257 HydrophobicContact CZ-CB 4.26Å; F173-F257 HydrophobicContact CZ-CD2 4.48Å; F173-F257 PolarHBondContact O-N 3.44Å; F174-F257 HydrophobicContact CD2-CD1 4.19Å; F174-F257 HydrophobicContact CE2-CD1 4.39Å; F174-F257 PolarHBondContact O-N 3.47Å; F174-F257 VanDerWaalsContact O-N 3.16Å; F257-L259 PolarHBondContact O-N 3.36Å; F257-A260 PolarHBondContact O-N 3.33Å; F257-F261 HydrophobicContact CD1-CB 4.13Å; F257-F261 HydrophobicContact CD2-CB 4.34Å; F257-F261 HydrophobicContact CE1-CB 3.8Å; F257-F261 HydrophobicContact CE1-CD1 4.38Å; F257-F261 HydrophobicContact CE1-CD2 4.48Å; F257-F261 AromaticContact CE1-CG 3.96Å; F257-F261 HydrophobicContact CE1-CG 3.96Å; F257-F261 HydrophobicContact CE2-CB 3.99Å; F257-F261 HydrophobicContact CE2-CD2 4.27Å; F257-F261 HydrophobicContact CE2-CG 4.34Å; F257-F261 HydrophobicContact CG-CB 4.42Å; F257-F261 HydrophobicContact CZ-CB 3.73Å; F257-F261 HydrophobicContact CZ-CD1 4.47Å; F257-F261 AromaticContact CZ-CD2 3.81Å; F257-F261 HydrophobicContact CZ-CD2 3.81Å; F257-F261 AromaticContact CZ-CG 3.73Å; F257-F261 HydrophobicContact CZ-CG 3.73Å; F257-F261 WeakPolarHBondContact O-CB 3.28Å; F257-F261 PolarHBondContact O-N 2.95Å
258M96.6Very high94.7Very high27 Ų2714.1 Ų14.113%0.1338%0.078CC..Hα-helixtrans-55.6-53.3-178.2-177.2-173.771.400112F13 F174 L175 G256 G262F13-M258 HydrophobicContact CD1-SD 4.37Å; F13-M258 HydrophobicContact CD2-SD 4.4Å; F13-M258 HydrophobicContact CE1-SD 3.69Å; F13-M258 HydrophobicContact CE2-CE 4.29Å; F13-M258 HydrophobicContact CE2-SD 3.75Å; F13-M258 HydrophobicContact CZ-CE 4.05Å; F13-M258 HydrophobicContact CZ-SD 3.33Å; F13-M258 WeakPolarHBondContact CZ-SD 3.27Å; F174-M258 HydrophobicContact CD1-CB 4.19Å; F174-M258 HydrophobicContact CD2-CB 4.28Å; F174-M258 HydrophobicContact CE1-CB 3.81Å; F174-M258 HydrophobicContact CE1-CG 3.93Å; F174-M258 HydrophobicContact CE1-SD 3.71Å; F174-M258 HydrophobicContact CE2-CB 3.91Å; F174-M258 HydrophobicContact CE2-CG 4.3Å; F174-M258 HydrophobicContact CG-CB 4.42Å; F174-M258 HydrophobicContact CZ-CB 3.65Å; F174-M258 HydrophobicContact CZ-CG 3.66Å; F174-M258 HydrophobicContact CZ-SD 3.97Å; F174-M258 VanDerWaalsContact O-CB 3.32Å; F174-M258 WeakPolarHBondContact O-CB 3.34Å; F174-M258 PolarHBondContact O-N 3.42Å; L175-M258 HydrophobicContact CD2-CE 3.91Å; L175-M258 HydrophobicContact CD2-SD 4.11Å; G256-M258 VanDerWaalsContact C-N 3.27Å; G256-M258 PolarHBondContact O-N 3.35Å; M258-G262 WeakPolarHBondContact O-CA 3.19Å; M258-G262 PolarHBondContact O-N 2.81Å
259L96.4Very high95.3Very high16 Ų1613.8 Ų13.88%0.0848%0.077CC..Hα-helixtrans-74.2-44.7179.4-69.2-173.6000111.1K189 D249 D253 G254 F255 G256 F257 F261 G262 D263K189-L259 HydrophobicContact CD-CD1 4.49Å; D249-L259 HydrophobicContact CB-CD1 4.41Å; D253-L259 HydrophobicContact CB-CD1 4.26Å; G254-L259 VanDerWaalsContact O-CD1 3.28Å; G254-L259 WeakPolarHBondContact O-CD1 3.38Å; F255-L259 HydrophobicContact CD2-CB 3.6Å; F255-L259 HydrophobicContact CD2-CD1 4.14Å; F255-L259 HydrophobicContact CE2-CB 3.76Å; G256-L259 PolarHBondContact O-N 3.44Å; F257-L259 PolarHBondContact O-N 3.36Å; L259-F261 PolarHBondContact O-N 3.05Å; L259-G262 PolarHBondContact O-N 2.93Å; L259-D263 VanDerWaalsContact O-CB 3.32Å; L259-D263 WeakPolarHBondContact O-CB 3.31Å; L259-D263 PolarHBondContact O-N 3.5Å
260A97.7Very high95.7Very high0 Ų012.9 Ų12.90%07%0.072CC..Hα-helixtrans-58.4-46.818000000112.3F144 F255 G256 F257 I264F144-A260 HydrophobicContact CD1-CB 4.37Å; F255-A260 HydrophobicContact CE2-CB 4.33Å; F255-A260 HydrophobicContact CZ-CB 4.05Å; G256-A260 VanDerWaalsContact O-CB 3.31Å; G256-A260 WeakPolarHBondContact O-CB 3.48Å; G256-A260 PolarHBondContact O-N 2.94Å; F257-A260 PolarHBondContact O-N 3.33Å; A260-I264 WeakPolarHBondContact O-CG1 3.19Å; A260-I264 PolarHBondContact O-N 3.33Å; A260-I264 VanDerWaalsContact O-N 3.13Å
261F98.4Very high96Very high2 Ų213.7 Ų13.71%0.0098%0.075CC..Hα-helixtrans-68.5-42.3175.2179-95.7000111.8L26 P27 M30 T138 A141 F257 L259 D263 A265 W266L26-F261 HydrophobicContact CB-CD1 4.14Å; L26-F261 HydrophobicContact CB-CE1 3.75Å; P27-F261 HydrophobicContact CB-CE2 4.26Å; P27-F261 HydrophobicContact CB-CZ 4.22Å; P27-F261 HydrophobicContact CG-CD2 4.45Å; P27-F261 HydrophobicContact CG-CE2 3.89Å; P27-F261 HydrophobicContact CG-CZ 3.97Å; M30-F261 HydrophobicContact CB-CZ 4.42Å; M30-F261 HydrophobicContact CE-CE2 4.07Å; M30-F261 HydrophobicContact CE-CZ 3.97Å; M30-F261 HydrophobicContact SD-CE2 4.48Å; M30-F261 HydrophobicContact SD-CZ 4.01Å; T138-F261 HydrophobicContact CG2-CD2 4.37Å; T138-F261 HydrophobicContact CG2-CE2 3.95Å; A141-F261 HydrophobicContact CB-CB 3.92Å; A141-F261 HydrophobicContact CB-CD2 4.1Å; F257-F261 HydrophobicContact CD1-CB 4.13Å; F257-F261 HydrophobicContact CD2-CB 4.34Å; F257-F261 HydrophobicContact CE1-CB 3.8Å; F257-F261 HydrophobicContact CE1-CD1 4.38Å; F257-F261 HydrophobicContact CE1-CD2 4.48Å; F257-F261 AromaticContact CE1-CG 3.96Å; F257-F261 HydrophobicContact CE1-CG 3.96Å; F257-F261 HydrophobicContact CE2-CB 3.99Å; F257-F261 HydrophobicContact CE2-CD2 4.27Å; F257-F261 HydrophobicContact CE2-CG 4.34Å; F257-F261 HydrophobicContact CG-CB 4.42Å; F257-F261 HydrophobicContact CZ-CB 3.73Å; F257-F261 HydrophobicContact CZ-CD1 4.47Å; F257-F261 AromaticContact CZ-CD2 3.81Å; F257-F261 HydrophobicContact CZ-CD2 3.81Å; F257-F261 AromaticContact CZ-CG 3.73Å; F257-F261 HydrophobicContact CZ-CG 3.73Å; F257-F261 WeakPolarHBondContact O-CB 3.28Å; F257-F261 PolarHBondContact O-N 2.95Å; L259-F261 PolarHBondContact O-N 3.05Å; F261-D263 VanDerWaalsContact C-N 3.33Å; F261-D263 PolarHBondContact O-N 3.38Å; F261-A265 HydrophobicContact CD2-CB 3.78Å; F261-A265 HydrophobicContact CE2-CB 3.65Å; F261-A265 HydrophobicContact CG-CB 4.42Å; F261-A265 HydrophobicContact CZ-CB 4.21Å; F261-A265 WeakPolarHBondContact O-CA 3.27Å; F261-A265 WeakPolarHBondContact O-CB 3.34Å; F261-A265 PolarHBondContact O-N 3.38Å; F261-W266 HydrophobicContact CD1-CB 4.31Å; F261-W266 HydrophobicContact CE1-CB 4.06Å; F261-W266 AromaticContact CE1-CE3 3.95Å; F261-W266 HydrophobicContact CE1-CE3 3.95Å; F261-W266 PolarHBondContact O-N 3Å
262G97.2Very high96.4Very high18 Ų1812.1 Ų12.119%0.1867%0.065CC..Iπ-helixtrans-51.3-52.9174.900000112M258 L259 W266 V267M258-G262 WeakPolarHBondContact O-CA 3.19Å; M258-G262 PolarHBondContact O-N 2.81Å; L259-G262 PolarHBondContact O-N 2.93Å; G262-W266 WeakPolarHBondContact O-CB 3.25Å; G262-W266 PolarHBondContact O-N 3.42Å; G262-V267 VanDerWaalsContact O-CG2 3.32Å; G262-V267 WeakPolarHBondContact O-CG2 3.34Å; G262-V267 PolarHBondContact O-N 3.02Å
263D97.3Very high97Very high20 Ų208.2 Ų8.211%0.1075%0.047CC..Iπ-helixtrans-71.2-52.3-174-66.4-22.5000112.5C192 E193 G197 L259 F261C192-D263 HydrophobicContact CB-CB 3.96Å; E193-D263 PolarHBondContact N-OD2 3.12Å; G197-D263 WeakPolarHBondContact CA-O 3.16Å; L259-D263 VanDerWaalsContact O-CB 3.32Å; L259-D263 WeakPolarHBondContact O-CB 3.31Å; L259-D263 PolarHBondContact O-N 3.5Å; F261-D263 VanDerWaalsContact C-N 3.33Å; F261-D263 PolarHBondContact O-N 3.38Å
264I96.6Very high97.3Very high4 Ų47.6 Ų7.62%0.0214%0.044CC..Iπ-helixtrans-90.6-21.8-167.882.3-169.2000113.4W66 T140 A141 C192 P196 A260 P268W66-I264 HydrophobicContact CH2-CB 4.02Å; W66-I264 HydrophobicContact CH2-CG1 4.37Å; W66-I264 VanDerWaalsContact CH2-O 3.32Å; W66-I264 WeakPolarHBondContact CH2-O 3.25Å; W66-I264 HydrophobicContact CZ2-CB 4.18Å; W66-I264 HydrophobicContact CZ2-CD1 4.27Å; W66-I264 HydrophobicContact CZ2-CG1 4.2Å; T140-I264 HydrophobicContact CG2-CD1 4.05Å; A141-I264 HydrophobicContact CB-CD1 3.81Å; A141-I264 HydrophobicContact CB-CG1 4.23Å; C192-I264 HydrophobicContact CB-CG2 4.12Å; P196-I264 HydrophobicContact CG-CG2 4.09Å; A260-I264 WeakPolarHBondContact O-CG1 3.19Å; A260-I264 PolarHBondContact O-N 3.33Å; A260-I264 VanDerWaalsContact O-N 3.13Å; I264-P268 WeakPolarHBondContact O-CG 3.34Å
265A97.9Very high97.5Very high0 Ų07.4 Ų7.40%04%0.042CC..Iπ-helixtrans-118.1-59.4-177.800000111.5M30 A137 F261 V267 P268 F269M30-A265 HydrophobicContact CE-CB 4.34Å; M30-A265 HydrophobicContact SD-CB 4.04Å; A137-A265 HydrophobicContact CB-CB 4.05Å; F261-A265 HydrophobicContact CD2-CB 3.78Å; F261-A265 HydrophobicContact CE2-CB 3.65Å; F261-A265 HydrophobicContact CG-CB 4.42Å; F261-A265 HydrophobicContact CZ-CB 4.21Å; F261-A265 WeakPolarHBondContact O-CA 3.27Å; F261-A265 WeakPolarHBondContact O-CB 3.34Å; F261-A265 PolarHBondContact O-N 3.38Å; A265-V267 PolarHBondContact O-N 3.22Å; A265-P268 WeakPolarHBondContact O-CD 3.44Å; A265-P268 WeakPolarHBondContact O-CG 3.35Å; A265-F269 HydrophobicContact CB-CD2 4.49Å; A265-F269 WeakPolarHBondContact O-CB 3.23Å; A265-F269 WeakPolarHBondContact O-CD2 3.21Å; A265-F269 PolarHBondContact O-N 3.5Å
266W98.3Very high97.6Very high11 Ų117.8 Ų7.84%0.0424%0.044CC..Iπ-helixtrans-58.9-53.6-171.9-177.3-93.9000112.6L26 T29 M30 F261 G262 T270 Y271 F374 Y378L26-W266 HydrophobicContact CD2-CH2 4.47Å; L26-W266 HydrophobicContact CD2-CZ3 4.25Å; L26-W266 WeakPolarHBondContact O-CZ3 3.42Å; T29-W266 HydrophobicContact CG2-CH2 3.87Å; T29-W266 HydrophobicContact CG2-CZ3 4.2Å; M30-W266 HydrophobicContact CB-CE3 4.12Å; M30-W266 HydrophobicContact CB-CZ3 4.22Å; F261-W266 HydrophobicContact CD1-CB 4.31Å; F261-W266 HydrophobicContact CE1-CB 4.06Å; F261-W266 AromaticContact CE1-CE3 3.95Å; F261-W266 HydrophobicContact CE1-CE3 3.95Å; F261-W266 PolarHBondContact O-N 3Å; G262-W266 WeakPolarHBondContact O-CB 3.25Å; G262-W266 PolarHBondContact O-N 3.42Å; W266-T270 HydrophobicContact CD2-CG2 3.85Å; W266-T270 HydrophobicContact CE3-CG2 3.88Å; W266-T270 HydrophobicContact CG-CG2 4.35Å; W266-T270 HydrophobicContact CH2-CG2 4.49Å; W266-T270 HydrophobicContact CZ2-CG2 4.44Å; W266-T270 HydrophobicContact CZ3-CG2 4.21Å; W266-T270 PolarHBondContact NE1-OG1 3.39Å; W266-T270 VanDerWaalsContact O-CB 3.29Å; W266-T270 WeakPolarHBondContact O-CB 3.41Å; W266-T270 WeakPolarHBondContact O-CG2 3.4Å; W266-T270 PolarHBondContact O-N 3.29Å; W266-T270 PolarHBondContact O-OG1 3.32Å; W266-Y271 AromaticContact CD1-CE1 3.95Å; W266-Y271 AromaticContact NE1-CE1 3.9Å; W266-F374 HydrophobicContact CH2-CE1 4.13Å; W266-F374 AromaticContact CH2-CZ 3.92Å; W266-F374 HydrophobicContact CH2-CZ 3.92Å; W266-F374 AromaticContact CZ2-CE1 3.91Å; W266-F374 HydrophobicContact CZ2-CE1 3.91Å; W266-F374 HydrophobicContact CZ2-CZ 4Å; W266-Y378 AromaticContact CE2-CE2 3.98Å; W266-Y378 AromaticContact CE2-CZ 3.75Å; W266-Y378 HydrophobicContact CZ2-CD1 4.32Å; W266-Y378 AromaticContact CZ2-CD2 3.8Å; W266-Y378 HydrophobicContact CZ2-CD2 3.8Å; W266-Y378 HydrophobicContact CZ2-CE1 4.22Å; W266-Y378 AromaticContact CZ2-CE2 3.67Å; W266-Y378 HydrophobicContact CZ2-CE2 3.67Å; W266-Y378 HydrophobicContact CZ2-CG 4.12Å; W266-Y378 AromaticContact CZ2-CZ 3.89Å; W266-Y378 AromaticContact NE1-CE1 3.31Å; W266-Y378 VanDerWaalsContact NE1-CE1 3.31Å; W266-Y378 AromaticContact NE1-CE2 3.9Å; W266-Y378 AromaticContact NE1-CZ 3.18Å; W266-Y378 PolarHBondContact NE1-OH 2.75Å; W266-Y378 VanDerWaalsContact NE1-OH 3.16Å
267V97.4Very high97.6Very high18 Ų187.7 Ų7.711%0.1094%0.043CC..Hα-helixtrans-54.7-61.4-178.8167.20000112.3L198 G262 A265 F269 Y271L198-V267 HydrophobicContact CD2-CG1 3.89Å; G262-V267 VanDerWaalsContact O-CG2 3.32Å; G262-V267 WeakPolarHBondContact O-CG2 3.34Å; G262-V267 PolarHBondContact O-N 3.02Å; A265-V267 PolarHBondContact O-N 3.22Å; V267-F269 PolarHBondContact O-N 3.31Å; V267-Y271 HydrophobicContact CG1-CD2 4.1Å; V267-Y271 HydrophobicContact CG1-CE2 4.38Å; V267-Y271 HydrophobicContact CG1-CG 4.44Å; V267-Y271 HydrophobicContact CG2-CE1 4.46Å; V267-Y271 HydrophobicContact CG2-CE2 4.19Å; V267-Y271 WeakPolarHBondContact O-CB 3.4Å; V267-Y271 PolarHBondContact O-N 2.85Å
268P97.3Very high97.5Very high3 Ų37.7 Ų7.72%0.0194%0.043CC..Hα-helixtrans-63.3-38.1-174.522-32.8000113.9W201 I204 I264 A265 S272W201-P268 HydrophobicContact CB-CB 4.42Å; I204-P268 HydrophobicContact CD1-CB 3.81Å; I264-P268 WeakPolarHBondContact O-CG 3.34Å; A265-P268 WeakPolarHBondContact O-CD 3.44Å; A265-P268 WeakPolarHBondContact O-CG 3.35Å; P268-S272 WeakPolarHBondContact O-CB 3.49Å; P268-S272 PolarHBondContact O-OG 3.24Å
269F98.1Very high97.5Very high7 Ų76.8 Ų6.83%0.0314%0.038CC..Hα-helixtrans-88.1-26.1-173.4-63.9-66.4000113.9M30 L34 L130 L133 A134 A137 I204 A265 V267 Q276M30-F269 HydrophobicContact CG-CB 4.16Å; M30-F269 HydrophobicContact SD-CB 3.86Å; M30-F269 HydrophobicContact SD-CD2 4.12Å; M30-F269 HydrophobicContact SD-CG 4.37Å; L34-F269 HydrophobicContact CD1-CB 4.38Å; L34-F269 HydrophobicContact CD2-CB 4.27Å; L130-F269 HydrophobicContact CD2-CD1 4.21Å; L130-F269 HydrophobicContact CD2-CE1 4.04Å; L133-F269 HydrophobicContact CB-CE1 3.96Å; L133-F269 HydrophobicContact CB-CZ 3.87Å; A134-F269 HydrophobicContact CB-CB 4.48Å; A134-F269 HydrophobicContact CB-CD1 3.88Å; A134-F269 HydrophobicContact CB-CD2 3.81Å; A134-F269 HydrophobicContact CB-CE1 4.06Å; A134-F269 HydrophobicContact CB-CE2 4.07Å; A134-F269 HydrophobicContact CB-CG 3.79Å; A134-F269 HydrophobicContact CB-CZ 4.18Å; A137-F269 HydrophobicContact CB-CE2 3.68Å; A137-F269 HydrophobicContact CB-CZ 4.41Å; I204-F269 HydrophobicContact CD1-CD1 4.02Å; I204-F269 HydrophobicContact CD1-CE1 3.88Å; I204-F269 HydrophobicContact CD1-CZ 4.48Å; A265-F269 HydrophobicContact CB-CD2 4.49Å; A265-F269 WeakPolarHBondContact O-CB 3.23Å; A265-F269 WeakPolarHBondContact O-CD2 3.21Å; A265-F269 PolarHBondContact O-N 3.5Å; V267-F269 PolarHBondContact O-N 3.31Å; F269-Q276 PolarHBondContact O-NE2 2.93Å
270T97.8Very high97.3Very high3 Ų311.7 Ų11.72%0.0186%0.056CC..Hα-helixtrans-98.7-29177.670.70000113.2M30 L33 W266 S272 L273M30-T270 HydrophobicContact CB-CG2 4.11Å; M30-T270 HydrophobicContact CG-CG2 3.78Å; L33-T270 HydrophobicContact CD1-CG2 4.02Å; W266-T270 HydrophobicContact CD2-CG2 3.85Å; W266-T270 HydrophobicContact CE3-CG2 3.88Å; W266-T270 HydrophobicContact CG-CG2 4.35Å; W266-T270 HydrophobicContact CH2-CG2 4.49Å; W266-T270 HydrophobicContact CZ2-CG2 4.44Å; W266-T270 HydrophobicContact CZ3-CG2 4.21Å; W266-T270 PolarHBondContact NE1-OG1 3.39Å; W266-T270 VanDerWaalsContact O-CB 3.29Å; W266-T270 WeakPolarHBondContact O-CB 3.41Å; W266-T270 WeakPolarHBondContact O-CG2 3.4Å; W266-T270 PolarHBondContact O-N 3.29Å; W266-T270 PolarHBondContact O-OG1 3.32Å; T270-S272 VanDerWaalsContact C-N 3.31Å; T270-S272 PolarHBondContact O-N 3.38Å; T270-L273 WeakPolarHBondContact O-CB 3.29Å; T270-L273 PolarHBondContact O-N 3.27Å
271Y97.8Very high97.1Very high20 Ų2012.8 Ų12.88%0.0786%0.061CC..Hα-helixtrans-81.4-15.7-178.9-67.419000112.1W201 Q230 W266 V267 Q274 Y375 Y378W201-Y271 VanDerWaalsContact CE2-CB 3.48Å; W201-Y271 HydrophobicContact CE3-CD2 4.25Å; W201-Y271 AromaticContact CH2-CD2 4Å; W201-Y271 HydrophobicContact CH2-CD2 4Å; W201-Y271 HydrophobicContact CZ2-CD2 4.22Å; W201-Y271 HydrophobicContact CZ2-CG 4.48Å; W201-Y271 HydrophobicContact CZ3-CD2 4Å; W201-Y271 PolarHBondContact NE1-O 3.49Å; W201-Y271 VanDerWaalsContact NE1-O 3.08Å; Q230-Y271 PolarHBondContact NE2-O 3.29Å; Q230-Y271 VanDerWaalsContact NE2-O 3.11Å; Q230-Y271 PolarHBondContact OE1-O 3.21Å; W266-Y271 AromaticContact CD1-CE1 3.95Å; W266-Y271 AromaticContact NE1-CE1 3.9Å; V267-Y271 HydrophobicContact CG1-CD2 4.1Å; V267-Y271 HydrophobicContact CG1-CE2 4.38Å; V267-Y271 HydrophobicContact CG1-CG 4.44Å; V267-Y271 HydrophobicContact CG2-CE1 4.46Å; V267-Y271 HydrophobicContact CG2-CE2 4.19Å; V267-Y271 WeakPolarHBondContact O-CB 3.4Å; V267-Y271 PolarHBondContact O-N 2.85Å; Y271-Q274 PolarHBondContact O-OE1 3.32Å; Y271-Q274 VanDerWaalsContact O-OE1 3.05Å; Y271-Y375 AromaticContact CD1-CD2 3.82Å; Y271-Y375 HydrophobicContact CD1-CD2 3.82Å; Y271-Y375 AromaticContact CD1-CE2 3.68Å; Y271-Y375 HydrophobicContact CD1-CE2 3.68Å; Y271-Y375 AromaticContact CD2-CE2 3.77Å; Y271-Y375 HydrophobicContact CD2-CE2 3.77Å; Y271-Y375 AromaticContact CE1-CD2 3.98Å; Y271-Y375 HydrophobicContact CE1-CD2 3.98Å; Y271-Y375 AromaticContact CE1-CE2 3.61Å; Y271-Y375 HydrophobicContact CE1-CE2 3.61Å; Y271-Y375 AromaticContact CE2-CE2 3.69Å; Y271-Y375 HydrophobicContact CE2-CE2 3.69Å; Y271-Y375 HydrophobicContact CG-CD2 4.15Å; Y271-Y375 AromaticContact CG-CE2 3.77Å; Y271-Y375 HydrophobicContact CG-CE2 3.77Å; Y271-Y375 AromaticContact CZ-CE2 3.61Å; Y271-Y378 HydrophobicContact CE1-CE1 4.09Å
272S97.9Very high96.8Very high0 Ų016.1 Ų16.10%08%0.083CC..THydrogen-bonded Turntrans-83.14.2169.355.30000113.3N205 P268 T270 Q274 A275 Q276N205-S272 VanDerWaalsContact OD1-CB 3.27Å; N205-S272 WeakPolarHBondContact OD1-CB 3.27Å; P268-S272 WeakPolarHBondContact O-CB 3.49Å; P268-S272 PolarHBondContact O-OG 3.24Å; T270-S272 VanDerWaalsContact C-N 3.31Å; T270-S272 PolarHBondContact O-N 3.38Å; S272-Q274 VanDerWaalsContact C-N 3.27Å; S272-Q274 PolarHBondContact O-N 2.96Å; S272-A275 PolarHBondContact O-N 3.21Å; S272-A275 VanDerWaalsContact O-N 3.13Å; S272-Q276 WeakPolarHBondContact O-CG 3.46Å; S272-Q276 PolarHBondContact O-N 2.73Å; S272-Q276 PolarHBondContact OG-NE2 2.97Å
273L97.9Very high96.5Very high1 Ų117.3 Ų17.31%0.0058%0.083CC..Hα-helixtrans-57.8-35.8-172.6-178.664000113.3L33 A37 T270 Q276 F277 L371 F374L33-L273 HydrophobicContact CB-CD1 4.37Å; L33-L273 HydrophobicContact CD2-CD2 4.14Å; A37-L273 HydrophobicContact CB-CD1 3.79Å; T270-L273 WeakPolarHBondContact O-CB 3.29Å; T270-L273 PolarHBondContact O-N 3.27Å; L273-Q276 PolarHBondContact O-N 3.03Å; L273-F277 VanDerWaalsContact O-CB 3.28Å; L273-F277 WeakPolarHBondContact O-CB 3.48Å; L273-F277 PolarHBondContact O-N 3.07Å; L273-L371 HydrophobicContact CD1-CD1 4.31Å; L273-L371 HydrophobicContact CD1-CD2 4.42Å; L273-L371 HydrophobicContact CD1-CG 4.23Å; L273-L371 HydrophobicContact CD2-CD1 4.11Å; L273-L371 HydrophobicContact CD2-CG 4.25Å; L273-L371 VanDerWaalsContact CD2-O 3.29Å; L273-L371 WeakPolarHBondContact CD2-O 3.49Å; L273-L371 HydrophobicContact CG-CG 4.47Å; L273-F374 HydrophobicContact CD2-CB 4.16Å; L273-F374 HydrophobicContact CD2-CD1 4.44Å
274Q98.1Very high96.3Very high0 Ų022.4 Ų22.40%012%0.118CC..Hα-helixtrans-64.9-45.1178.4-63.484.4-3.800111.3V226 Y271 S272 F277 L278 P372V226-Q274 HydrophobicContact CG1-CB 3.76Å; V226-Q274 HydrophobicContact CG2-CB 4.13Å; Y271-Q274 PolarHBondContact O-OE1 3.32Å; Y271-Q274 VanDerWaalsContact O-OE1 3.05Å; S272-Q274 VanDerWaalsContact C-N 3.27Å; S272-Q274 PolarHBondContact O-N 2.96Å; Q274-F277 PolarHBondContact O-N 3.19Å; Q274-L278 WeakPolarHBondContact O-CG 3.28Å; Q274-L278 PolarHBondContact O-N 2.97Å; Q274-P372 HydrophobicContact CG-CB 4.3Å; Q274-P372 PolarHBondContact NE2-O 3.46Å
275A98.1Very high96.2Very high0 Ų023.9 Ų23.90%013%0.125CC..Hα-helixtrans-66.9-39.9175.100000111.4L208 M223 V226 S272 F277 L278 L279L208-A275 HydrophobicContact CB-CB 4.18Å; L208-A275 HydrophobicContact CD1-CB 3.69Å; M223-A275 WeakPolarHBondContact CE-O 3.27Å; M223-A275 HydrophobicContact SD-CB 3.86Å; V226-A275 HydrophobicContact CG1-CB 4.25Å; S272-A275 PolarHBondContact O-N 3.21Å; S272-A275 VanDerWaalsContact O-N 3.13Å; A275-F277 VanDerWaalsContact C-N 3.33Å; A275-F277 PolarHBondContact O-N 3.39Å; A275-L278 PolarHBondContact O-N 3.43Å; A275-L279 PolarHBondContact O-N 3.39Å; A275-L279 VanDerWaalsContact O-N 3.13Å
276Q97.4Very high96.1Very high12 Ų1226 Ų266%0.05615%0.147CC..Hα-helixtrans-60.8-43175-68.3178.955.800111.7A37 L130 L208 F269 S272 L273A37-Q276 HydrophobicContact CB-CB 4.13Å; L130-Q276 HydrophobicContact CD1-CG 4.09Å; L208-Q276 HydrophobicContact CD1-CB 4.44Å; L208-Q276 HydrophobicContact CD1-CG 3.58Å; L208-Q276 HydrophobicContact CD2-CG 4.14Å; F269-Q276 PolarHBondContact O-NE2 2.93Å; S272-Q276 WeakPolarHBondContact O-CG 3.46Å; S272-Q276 PolarHBondContact O-N 2.73Å; S272-Q276 PolarHBondContact OG-NE2 2.97Å; L273-Q276 PolarHBondContact O-N 3.03Å
277F97.2Very high96Very high0 Ų031.4 Ų31.40%018%0.176CC..Hα-helixtrans-63.2-51.2176.8174.1-93.8000111.4A42 L273 Q274 A275 L279 R280 H281 Q283 C365 H369 L371 P372A42-F277 HydrophobicContact CB-CD2 4.07Å; A42-F277 HydrophobicContact CB-CE2 3.77Å; L273-F277 VanDerWaalsContact O-CB 3.28Å; L273-F277 WeakPolarHBondContact O-CB 3.48Å; L273-F277 PolarHBondContact O-N 3.07Å; Q274-F277 PolarHBondContact O-N 3.19Å; A275-F277 VanDerWaalsContact C-N 3.33Å; A275-F277 PolarHBondContact O-N 3.39Å; F277-L279 PolarHBondContact O-N 3.29Å; F277-R280 PolarHBondContact O-N 2.85Å; F277-H281 HydrophobicContact CD1-CB 4.15Å; F277-H281 HydrophobicContact CD2-CB 4.14Å; F277-H281 AromaticContact CD2-CD2 3.45Å; F277-H281 VanDerWaalsContact CD2-CD2 3.45Å; F277-H281 WeakPolarHBondContact CD2-CD2 3.42Å; F277-H281 AromaticContact CD2-CG 3.96Å; F277-H281 HydrophobicContact CE1-CB 3.7Å; F277-H281 HydrophobicContact CE2-CB 3.7Å; F277-H281 AromaticContact CE2-CD2 3.49Å; F277-H281 VanDerWaalsContact CE2-CD2 3.49Å; F277-H281 WeakPolarHBondContact CE2-CD2 3.49Å; F277-H281 AromaticContact CE2-CG 3.57Å; F277-H281 HydrophobicContact CG-CB 4.34Å; F277-H281 HydrophobicContact CZ-CB 3.45Å; F277-H281 VanDerWaalsContact CZ-CB 3.45Å; F277-H281 AromaticContact CZ-CG 3.86Å; F277-H281 WeakPolarHBondContact O-CB 3.45Å; F277-H281 PolarHBondContact O-CD2 2.89Å; F277-H281 PolarHBondContact O-N 2.9Å; F277-Q283 HydrophobicContact CE1-CG 4.28Å; F277-C365 HydrophobicContact CD1-CB 3.69Å; F277-C365 HydrophobicContact CE1-CB 3.81Å; F277-C365 WeakPolarHBondContact CE1-O 3.44Å; F277-H369 HydrophobicContact CE2-CB 3.79Å; F277-H369 AromaticContact CE2-CD2 3.88Å; F277-H369 AromaticContact CE2-CG 3.73Å; F277-H369 HydrophobicContact CZ-CB 3.86Å; F277-H369 AromaticContact CZ-CD2 3.51Å; F277-H369 AromaticContact CZ-CG 3.77Å; F277-L371 HydrophobicContact CD2-CD2 4.37Å; F277-P372 HydrophobicContact CB-CG 4.21Å; F277-P372 HydrophobicContact CD1-CG 3.64Å; F277-P372 HydrophobicContact CD2-CG 3.92Å; F277-P372 HydrophobicContact CE1-CG 3.93Å; F277-P372 HydrophobicContact CE2-CG 4.19Å; F277-P372 HydrophobicContact CG-CG 3.64Å; F277-P372 HydrophobicContact CZ-CG 4.19Å
278L96.9Very high95.9Very high0 Ų035.8 Ų35.80%021%0.205CC..Hα-helixtrans-58.9-33.5-178.8-74172.7000112.9A222 M223 V226 Q274 A275 R280 Q283A222-L278 HydrophobicContact CB-CD1 3.9Å; A222-L278 HydrophobicContact CB-CD2 3.87Å; M223-L278 HydrophobicContact CE-CB 3.7Å; V226-L278 HydrophobicContact CB-CD1 4.45Å; V226-L278 HydrophobicContact CG2-CD1 3.79Å; Q274-L278 WeakPolarHBondContact O-CG 3.28Å; Q274-L278 PolarHBondContact O-N 2.97Å; A275-L278 PolarHBondContact O-N 3.43Å; L278-R280 PolarHBondContact O-N 3.49Å; L278-Q283 HydrophobicContact CD2-CB 4.18Å; L278-Q283 HydrophobicContact CD2-CG 3.89Å
279L95.6Very high95.9Very high8 Ų841.2 Ų41.24%0.04223%0.231CC..Hα-helixtrans-58.8-36.4177.7-175.864.8000112.2P127 L208 K211 E212 L215 R216 M223 A275 F277P127-L279 HydrophobicContact CB-CD2 4.27Å; L208-L279 HydrophobicContact CD2-CD2 3.75Å; K211-L279 HydrophobicContact CB-CD1 4.19Å; K211-L279 HydrophobicContact CB-CD2 4.38Å; K211-L279 HydrophobicContact CG-CD1 4.03Å; K211-L279 HydrophobicContact CG-CD2 3.95Å; E212-L279 HydrophobicContact CB-CD1 3.79Å; L215-L279 HydrophobicContact CD1-CD1 4.04Å; R216-L279 PolarHBondContact NH1-O 3.08Å; R216-L279 VanDerWaalsContact NH1-O 3.11Å; R216-L279 PolarHBondContact NH2-O 2.84Å; M223-L279 HydrophobicContact CE-CB 4.4Å; A275-L279 PolarHBondContact O-N 3.39Å; A275-L279 VanDerWaalsContact O-N 3.13Å; F277-L279 PolarHBondContact O-N 3.29Å
280R92.9Very high95.9Very high118 Ų11841.1 Ų41.145%0.44523%0.232SC..Hα-helixtrans-102.4-22.8-177.8-63.5-68.7-179.1157.3-3.9113.4E128 F277 L278 P282E128-R280 IonicContact OE1-NH2 2.81Å; E128-R280 PolarHBondContact OE1-NH2 3.28Å; E128-R280 IonicContact OE2-NH2 2.69Å; F277-R280 PolarHBondContact O-N 2.85Å; L278-R280 PolarHBondContact O-N 3.49Å; R280-P282 WeakPolarHBondContact O-CD 3.45Å
281H93.1Very high95.9Very high24 Ų2444.8 Ų44.811%0.11126%0.258CS..SBendtrans-124.774.4-176.1-57.4-71000110.8S39 G40 F277 Q283S39-H281 PolarHBondContact O-CE1 2.91Å; S39-H281 PolarHBondContact O-NE2 2.68Å; G40-H281 PolarHBondContact O-CE1 2.97Å; F277-H281 HydrophobicContact CD1-CB 4.15Å; F277-H281 HydrophobicContact CD2-CB 4.14Å; F277-H281 AromaticContact CD2-CD2 3.45Å; F277-H281 VanDerWaalsContact CD2-CD2 3.45Å; F277-H281 WeakPolarHBondContact CD2-CD2 3.42Å; F277-H281 AromaticContact CD2-CG 3.96Å; F277-H281 HydrophobicContact CE1-CB 3.7Å; F277-H281 HydrophobicContact CE2-CB 3.7Å; F277-H281 AromaticContact CE2-CD2 3.49Å; F277-H281 VanDerWaalsContact CE2-CD2 3.49Å; F277-H281 WeakPolarHBondContact CE2-CD2 3.49Å; F277-H281 AromaticContact CE2-CG 3.57Å; F277-H281 HydrophobicContact CG-CB 4.34Å; F277-H281 HydrophobicContact CZ-CB 3.45Å; F277-H281 VanDerWaalsContact CZ-CB 3.45Å; F277-H281 AromaticContact CZ-CG 3.86Å; F277-H281 WeakPolarHBondContact O-CB 3.45Å; F277-H281 PolarHBondContact O-CD2 2.89Å; F277-H281 PolarHBondContact O-N 2.9Å; H281-Q283 WeakPolarHBondContact O-CG 3.41Å; H281-Q283 PolarHBondContact O-N 2.88Å; H281-Q283 PolarHBondContact O-NE2 3.28Å; H281-Q283 VanDerWaalsContact O-NE2 3.09Å
282P91.4Very high95.9Very high72 Ų7246 Ų4647%0.46827%0.272SS..  trans-57.3130.9-178.9-23.834.6000111.4R280R280-P282 WeakPolarHBondContact O-CD 3.45Å
283Q92.3Very high96Very high42 Ų4246.1 Ų46.120%0.19627%0.272CS..  trans-112129.4178.8-60.4-59.1-47.200110.1F277 L278 H281 L285 C365F277-Q283 HydrophobicContact CE1-CG 4.28Å; L278-Q283 HydrophobicContact CD2-CB 4.18Å; L278-Q283 HydrophobicContact CD2-CG 3.89Å; H281-Q283 WeakPolarHBondContact O-CG 3.41Å; H281-Q283 PolarHBondContact O-N 2.88Å; H281-Q283 PolarHBondContact O-NE2 3.28Å; H281-Q283 VanDerWaalsContact O-NE2 3.09Å; Q283-L285 PolarHBondContact O-N 3.41Å; Q283-C365 WeakPolarHBondContact CG-O 3.28Å
284P91.3Very high96Very high128 Ų12848.3 Ų48.383%0.83129%0.288SS*.  trans-69.7121.8171.229.1-31.8000108.9
285L95Very high96Very high34 Ų3453.5 Ų53.518%0.17831%0.314CS..  trans-125.3108.2177.1-173.365.9000110.2L221 A222 L225 Q283 M289 A290 I293L221-L285 HydrophobicContact CD2-CD2 4.42Å; L221-L285 HydrophobicContact CD2-CG 4.47Å; L221-L285 HydrophobicContact CG-CD2 4.22Å; A222-L285 HydrophobicContact CB-CB 4.43Å; A222-L285 HydrophobicContact CB-CD2 4.13Å; L225-L285 HydrophobicContact CD1-CD2 3.62Å; Q283-L285 PolarHBondContact O-N 3.41Å; L285-M289 HydrophobicContact CD1-CB 3.87Å; L285-M289 HydrophobicContact CD1-CG 3.67Å; L285-A290 HydrophobicContact CD2-CB 4.05Å; L285-A290 HydrophobicContact CG-CB 4.16Å; L285-I293 HydrophobicContact CD1-CD1 3.99Å
286G95.3Very high96Very high44 Ų4456 Ų5645%0.45433%0.328SS..  trans-77.4153.9174.200000112.2P288 M289 A290G286-P288 VanDerWaalsContact C-CD 3.47Å; G286-M289 PolarHBondContact O-N 3.08Å; G286-A290 PolarHBondContact O-N 3.48Å
287L96.3Very high96.1Very high126 Ų12655.9 Ų55.966%0.6633%0.327SS*.Hα-helixtrans-53.7-42-179.5-65.8175.2000114.2L221 M289 A290 S291L221-L287 HydrophobicContact CD2-CD2 3.99Å; L287-M289 PolarHBondContact O-N 2.84Å; L287-A290 WeakPolarHBondContact O-CB 3.25Å; L287-A290 PolarHBondContact O-N 3.36Å; L287-S291 PolarHBondContact O-N 3.09Å; L287-S291 PolarHBondContact O-OG 2.92Å; L287-S291 VanDerWaalsContact O-OG 3.09Å
288P96.9Very high96.1Very high109 Ų10958.3 Ų58.371%0.70835%0.347SS*.Hα-helixtrans-61-42.8179.5-25.235.6000113.2G286 S291 A292G286-P288 VanDerWaalsContact C-CD 3.47Å; P288-S291 PolarHBondContact O-N 3.07Å; P288-A292 PolarHBondContact O-N 2.84Å; P288-A292 VanDerWaalsContact O-N 3.09Å
289M96.8Very high96.2Very high117 Ų11762 Ų6258%0.57637%0.366SS*.Hα-helixtrans-68.6-41.8177.1-173.362.971.800110.8L285 G286 L287 S291 A292 I293L285-M289 HydrophobicContact CD1-CB 3.87Å; L285-M289 HydrophobicContact CD1-CG 3.67Å; G286-M289 PolarHBondContact O-N 3.08Å; L287-M289 PolarHBondContact O-N 2.84Å; M289-S291 VanDerWaalsContact C-N 3.32Å; M289-S291 PolarHBondContact O-N 3.29Å; M289-A292 PolarHBondContact O-N 2.69Å; M289-I293 HydrophobicContact CG-CD1 4.07Å; M289-I293 VanDerWaalsContact O-CG1 3.29Å; M289-I293 WeakPolarHBondContact O-CG1 3.45Å; M289-I293 PolarHBondContact O-N 3.25Å
290A97.8Very high96.4Very high6 Ų661.6 Ų61.65%0.0536%0.364CS..Hα-helixtrans-57.6-44.117400000112L221 L225 L285 G286 L287 A292 I293 C294L221-A290 HydrophobicContact CD2-CB 3.62Å; L221-A290 HydrophobicContact CG-CB 4.31Å; L225-A290 HydrophobicContact CD1-CB 3.96Å; L285-A290 HydrophobicContact CD2-CB 4.05Å; L285-A290 HydrophobicContact CG-CB 4.16Å; G286-A290 PolarHBondContact O-N 3.48Å; L287-A290 WeakPolarHBondContact O-CB 3.25Å; L287-A290 PolarHBondContact O-N 3.36Å; A290-A292 PolarHBondContact O-N 2.89Å; A290-I293 PolarHBondContact O-N 3.46Å; A290-C294 WeakPolarHBondContact O-CB 3.32Å; A290-C294 PolarHBondContact O-N 3.4Å; A290-C294 PolarHBondContact O-SG 3.27Å
291S98.1Very high96.6Very high79 Ų7958.8 Ų58.855%0.55235%0.354SS*.Hα-helixtrans-61.8-41.9176.2-62.70000112.4L287 P288 M289 C294 L295L287-S291 PolarHBondContact O-N 3.09Å; L287-S291 PolarHBondContact O-OG 2.92Å; L287-S291 VanDerWaalsContact O-OG 3.09Å; P288-S291 PolarHBondContact O-N 3.07Å; M289-S291 VanDerWaalsContact C-N 3.32Å; M289-S291 PolarHBondContact O-N 3.29Å; S291-C294 PolarHBondContact O-N 3.33Å; S291-L295 PolarHBondContact O-N 3.18Å
292A98.3Very high96.9Very high45 Ų4565 Ų6537%0.37238%0.378SS..Hα-helixtrans-62.8-44.4175.200000111.7P288 M289 A290 C294 L295 I296P288-A292 PolarHBondContact O-N 2.84Å; P288-A292 VanDerWaalsContact O-N 3.09Å; M289-A292 PolarHBondContact O-N 2.69Å; A290-A292 PolarHBondContact O-N 2.89Å; A292-C294 PolarHBondContact O-N 3.23Å; A292-L295 WeakPolarHBondContact O-CB 3.25Å; A292-L295 PolarHBondContact O-N 2.91Å; A292-I296 WeakPolarHBondContact O-CG1 3.44Å; A292-I296 PolarHBondContact O-N 3.21Å
293I98.5Very high97.2Very high3 Ų362.6 Ų62.62%0.01536%0.36CS..Hα-helixtrans-61.9-44.6176.4-65.3167.5000110.9F229 L285 M289 A290 L295 I296 N297 A360 L363 P364F229-I293 HydrophobicContact CE2-CG2 3.7Å; F229-I293 HydrophobicContact CZ-CG2 4.13Å; L285-I293 HydrophobicContact CD1-CD1 3.99Å; M289-I293 HydrophobicContact CG-CD1 4.07Å; M289-I293 VanDerWaalsContact O-CG1 3.29Å; M289-I293 WeakPolarHBondContact O-CG1 3.45Å; M289-I293 PolarHBondContact O-N 3.25Å; A290-I293 PolarHBondContact O-N 3.46Å; I293-L295 VanDerWaalsContact C-N 3.29Å; I293-L295 PolarHBondContact O-N 3.37Å; I293-I296 PolarHBondContact O-N 3.07Å; I293-N297 PolarHBondContact O-N 2.95Å; I293-A360 HydrophobicContact CG2-CB 4.43Å; I293-A360 WeakPolarHBondContact CG2-O 3.33Å; I293-L363 HydrophobicContact CD1-CB 3.77Å; I293-L363 HydrophobicContact CG1-CB 3.79Å; I293-L363 HydrophobicContact CG1-CD1 4.13Å; I293-L363 HydrophobicContact CG2-CB 4.36Å; I293-P364 HydrophobicContact CD1-CG 4.34Å; I293-P364 HydrophobicContact CG2-CG 4.16Å
294C98.6Very high97.4Very high48 Ų4861.6 Ų61.632%0.32436%0.355SS..Hα-helixtrans-58.6-40.8174.9-73.10000112L225 A290 S291 A292 N297 A298L225-C294 VanDerWaalsContact CD2-SG 3.57Å; A290-C294 WeakPolarHBondContact O-CB 3.32Å; A290-C294 PolarHBondContact O-N 3.4Å; A290-C294 PolarHBondContact O-SG 3.27Å; S291-C294 PolarHBondContact O-N 3.33Å; A292-C294 PolarHBondContact O-N 3.23Å; C294-N297 PolarHBondContact O-N 2.91Å; C294-A298 VanDerWaalsContact O-CB 3.31Å; C294-A298 WeakPolarHBondContact O-CB 3.48Å; C294-A298 PolarHBondContact O-N 3.22Å
295L98.6Very high97.6Very high108 Ų10857 Ų5757%0.56532%0.321SS*.Hα-helixtrans-63.9-44.3175.9179.962.2000111.5S291 A292 I293 N297 A298 I299S291-L295 PolarHBondContact O-N 3.18Å; A292-L295 WeakPolarHBondContact O-CB 3.25Å; A292-L295 PolarHBondContact O-N 2.91Å; I293-L295 VanDerWaalsContact C-N 3.29Å; I293-L295 PolarHBondContact O-N 3.37Å; L295-N297 PolarHBondContact O-N 2.82Å; L295-A298 PolarHBondContact O-N 3.06Å; L295-I299 HydrophobicContact CD1-CD1 4.16Å; L295-I299 HydrophobicContact CD1-CG1 4.33Å; L295-I299 HydrophobicContact CG-CD1 3.97Å; L295-I299 VanDerWaalsContact O-CG1 3.29Å; L295-I299 WeakPolarHBondContact O-CG1 3.47Å; L295-I299 PolarHBondContact O-N 3.01Å
296I98.6Very high97.7Very high54 Ų5456.2 Ų56.228%0.27732%0.322SS..Hα-helixtrans-59.1-48.1175.6-64.1166.4000110A292 I293 A298 I299 G300 I356 A360 L363A292-I296 WeakPolarHBondContact O-CG1 3.44Å; A292-I296 PolarHBondContact O-N 3.21Å; I293-I296 PolarHBondContact O-N 3.07Å; I296-A298 VanDerWaalsContact C-N 3.34Å; I296-A298 PolarHBondContact O-N 3.1Å; I296-I299 PolarHBondContact O-N 3.48Å; I296-G300 PolarHBondContact O-N 2.92Å; I296-I356 HydrophobicContact CG2-CG2 3.68Å; I296-I356 VanDerWaalsContact O-CG2 3.26Å; I296-I356 WeakPolarHBondContact O-CG2 3.41Å; I296-A360 HydrophobicContact CB-CB 4.33Å; I296-A360 HydrophobicContact CG2-CB 3.97Å; I296-L363 HydrophobicContact CD1-CD1 3.74Å
297N98.5Very high97.7Very high8 Ų854.1 Ų54.14%0.04330%0.301CS..Hα-helixtrans-60.5-43.2177.4-172.473.1000111.8F229 I293 C294 L295 I299 G300 Y301 A360 W361F229-N297 HydrophobicContact CD1-CB 4.17Å; F229-N297 WeakPolarHBondContact CD1-ND2 3.49Å; F229-N297 HydrophobicContact CD2-CB 4.39Å; F229-N297 HydrophobicContact CE1-CB 4Å; F229-N297 HydrophobicContact CE2-CB 4.23Å; F229-N297 HydrophobicContact CG-CB 4.37Å; F229-N297 HydrophobicContact CZ-CB 4.03Å; I293-N297 PolarHBondContact O-N 2.95Å; C294-N297 PolarHBondContact O-N 2.91Å; L295-N297 PolarHBondContact O-N 2.82Å; N297-I299 PolarHBondContact O-N 3.03Å; N297-G300 PolarHBondContact O-N 2.56Å; N297-Y301 WeakPolarHBondContact O-CB 3.44Å; N297-Y301 PolarHBondContact O-N 3.18Å; N297-A360 HydrophobicContact CB-CB 3.68Å; N297-W361 PolarHBondContact OD1-NE1 3.03Å
298A98.5Very high97.7Very high51 Ų5149 Ų4942%0.42127%0.274SS..Hα-helixtrans-63.6-40.5178.900000112.3C294 L295 I296 Y302C294-A298 VanDerWaalsContact O-CB 3.31Å; C294-A298 WeakPolarHBondContact O-CB 3.48Å; C294-A298 PolarHBondContact O-N 3.22Å; L295-A298 PolarHBondContact O-N 3.06Å; I296-A298 VanDerWaalsContact C-N 3.34Å; I296-A298 PolarHBondContact O-N 3.1Å; A298-Y302 VanDerWaalsContact O-CB 3.27Å; A298-Y302 WeakPolarHBondContact O-CB 3.41Å; A298-Y302 PolarHBondContact O-N 3.25Å
299I98.5Very high97.5Very high78 Ų7845.9 Ų45.940%0.425%0.254SS..Hα-helixtrans-62.7-48.8174.3-69.3165.2000110.2L295 I296 N297 Y301 Y302 I303L295-I299 HydrophobicContact CD1-CD1 4.16Å; L295-I299 HydrophobicContact CD1-CG1 4.33Å; L295-I299 HydrophobicContact CG-CD1 3.97Å; L295-I299 VanDerWaalsContact O-CG1 3.29Å; L295-I299 WeakPolarHBondContact O-CG1 3.47Å; L295-I299 PolarHBondContact O-N 3.01Å; I296-I299 PolarHBondContact O-N 3.48Å; N297-I299 PolarHBondContact O-N 3.03Å; I299-Y301 PolarHBondContact O-N 3.26Å; I299-Y302 PolarHBondContact O-N 3.42Å; I299-I303 HydrophobicContact CG2-CD1 3.92Å; I299-I303 WeakPolarHBondContact O-CG1 3.39Å; I299-I303 PolarHBondContact O-N 3.26Å
300G98.3Very high97.4Very high0 Ų041.7 Ų41.70%023%0.234CC..Hα-helixtrans-58-47.6177.800000112.1I296 N297 Y302 I303 F304 G353I296-G300 PolarHBondContact O-N 2.92Å; N297-G300 PolarHBondContact O-N 2.56Å; G300-Y302 PolarHBondContact O-N 2.75Å; G300-I303 PolarHBondContact O-N 3.13Å; G300-F304 WeakPolarHBondContact O-CB 3.37Å; G300-F304 PolarHBondContact O-N 2.84Å; G300-G353 WeakPolarHBondContact CA-O 3.46Å; G300-G353 VanDerWaalsContact O-CA 3.27Å; G300-G353 WeakPolarHBondContact O-CA 3.41Å
301Y98.3Very high97.1Very high59 Ų5943.1 Ų43.123%0.23124%0.238CC..Hα-helixtrans-62.7-43177.2-177.3-103.9000112.4L232 D236 N297 I299 I303 F304 R305 M357L232-Y301 HydrophobicContact CD2-CD2 4.39Å; L232-Y301 HydrophobicContact CD2-CG 4.48Å; L232-Y301 HydrophobicContact CG-CE2 4.46Å; D236-Y301 HydrophobicContact CB-CE2 4.11Å; D236-Y301 PolarHBondContact OD1-OH 3.39Å; N297-Y301 WeakPolarHBondContact O-CB 3.44Å; N297-Y301 PolarHBondContact O-N 3.18Å; I299-Y301 PolarHBondContact O-N 3.26Å; Y301-I303 PolarHBondContact O-N 3.42Å; Y301-F304 PolarHBondContact O-N 3.37Å; Y301-R305 HydrophobicContact CE1-CB 4.2Å; Y301-R305 HydrophobicContact CE1-CG 4.35Å; Y301-R305 HydrophobicContact CE2-CB 4.22Å; Y301-R305 VanDerWaalsContact O-CB 3.26Å; Y301-R305 WeakPolarHBondContact O-CB 3.29Å; Y301-R305 PolarHBondContact O-N 3.12Å; Y301-M357 HydrophobicContact CD2-SD 4.09Å
302Y98.2Very high96.7Very high155 Ų15540.8 Ų40.861%0.60822%0.22SC*.Hα-helixtrans-59.6-45.6178176-106.4000111.8A298 I299 G300 G306 W342A298-Y302 VanDerWaalsContact O-CB 3.27Å; A298-Y302 WeakPolarHBondContact O-CB 3.41Å; A298-Y302 PolarHBondContact O-N 3.25Å; I299-Y302 PolarHBondContact O-N 3.42Å; G300-Y302 PolarHBondContact O-N 2.75Å; Y302-G306 WeakPolarHBondContact O-CA 3.44Å; Y302-G306 PolarHBondContact O-N 3.11Å; Y302-W342 AromaticContact CD1-CH2 3.94Å; Y302-W342 HydrophobicContact CD1-CH2 3.94Å; Y302-W342 HydrophobicContact CD1-CZ2 4.07Å; Y302-W342 AromaticContact CE1-CH2 3.57Å; Y302-W342 HydrophobicContact CE1-CH2 3.57Å; Y302-W342 AromaticContact CE1-CZ2 3.51Å; Y302-W342 HydrophobicContact CE1-CZ2 3.51Å; Y302-W342 AromaticContact CZ-CZ2 4Å
303I98.1Very high96.4Very high20 Ų2039.9 Ų39.910%0.10321%0.21CC..Hα-helixtrans-64.5-50.3176.4-63.8168000110I299 G300 Y301 A307 W342 P349 I356I299-I303 HydrophobicContact CG2-CD1 3.92Å; I299-I303 WeakPolarHBondContact O-CG1 3.39Å; I299-I303 PolarHBondContact O-N 3.26Å; G300-I303 PolarHBondContact O-N 3.13Å; Y301-I303 PolarHBondContact O-N 3.42Å; I303-A307 WeakPolarHBondContact O-CB 3.49Å; I303-A307 PolarHBondContact O-N 3.45Å; I303-W342 HydrophobicContact CB-CZ3 4.38Å; I303-W342 HydrophobicContact CG1-CH2 4.02Å; I303-W342 HydrophobicContact CG1-CZ3 3.9Å; I303-W342 HydrophobicContact CG2-CE3 4.31Å; I303-W342 HydrophobicContact CG2-CZ3 4.18Å; I303-P349 VanDerWaalsContact CG2-O 3.25Å; I303-P349 WeakPolarHBondContact CG2-O 3.47Å; I303-I356 HydrophobicContact CD1-CD1 3.9Å
304F97.3Very high96.1Very high21 Ų2140.7 Ų40.79%0.09221%0.213CC..Hα-helixtrans-58.2-54.6-178171.6-97.9000112.3Y233 G300 Y301 N308 N350 D354 M357Y233-F304 HydrophobicContact CE2-CZ 4.38Å; G300-F304 WeakPolarHBondContact O-CB 3.37Å; G300-F304 PolarHBondContact O-N 2.84Å; Y301-F304 PolarHBondContact O-N 3.37Å; F304-N308 VanDerWaalsContact CE2-ND2 3.3Å; F304-N308 WeakPolarHBondContact CE2-ND2 3.18Å; F304-N308 WeakPolarHBondContact CZ-ND2 3.44Å; F304-N308 WeakPolarHBondContact O-CB 3.1Å; F304-N308 PolarHBondContact O-N 2.95Å; F304-N308 VanDerWaalsContact O-N 3.1Å; F304-N308 PolarHBondContact O-ND2 2.91Å; F304-N308 VanDerWaalsContact O-ND2 3.09Å; F304-N350 HydrophobicContact CD2-CB 4.22Å; F304-N350 WeakPolarHBondContact CD2-O 3.3Å; F304-D354 HydrophobicContact CD2-CB 4.48Å; F304-D354 VanDerWaalsContact CD2-CG 3.45Å; F304-D354 WeakPolarHBondContact CD2-OD1 3.14Å; F304-D354 WeakPolarHBondContact CE2-OD1 3.08Å; F304-D354 VanDerWaalsContact CE2-OD2 3.3Å; F304-D354 WeakPolarHBondContact CE2-OD2 3.5Å; F304-M357 HydrophobicContact CB-CE 3.75Å; F304-M357 HydrophobicContact CD1-CE 4.04Å; F304-M357 HydrophobicContact CD2-CE 4.14Å; F304-M357 HydrophobicContact CG-CE 3.72Å
305R96.2Very high95.5Very high31 Ų3145.3 Ų45.312%0.11722%0.224CC..Hα-helixtrans-71.2-39.9-177.817847.455.6-162.1-3.3110.9D236 H240 Y301 N308 S309D236-R305 IonicContact OD1-CZ 3.56Å; D236-R305 VanDerWaalsContact OD1-CZ 3.28Å; D236-R305 IonicContact OD1-NE 3.34Å; D236-R305 PolarHBondContact OD1-NE 3.44Å; D236-R305 IonicContact OD1-NH2 2.99Å; D236-R305 PolarHBondContact OD1-NH2 3.16Å; D236-R305 VanDerWaalsContact OD1-NH2 3.12Å; D236-R305 IonicContact OD2-CZ 3.93Å; D236-R305 IonicContact OD2-NE 3.6Å; D236-R305 PolarHBondContact OD2-NE 3.17Å; D236-R305 IonicContact OD2-NH2 2.93Å; D236-R305 PolarHBondContact OD2-NH2 2.91Å; H240-R305 PolarHBondContact CD2-NH1 2.8Å; H240-R305 PolarHBondContact CE1-NH1 2.89Å; H240-R305 PolarHBondContact ND1-NH1 3.46Å; H240-R305 PolarHBondContact ND1-NH2 3.14Å; H240-R305 PolarHBondContact NE2-NH1 3.24Å; Y301-R305 HydrophobicContact CE1-CB 4.2Å; Y301-R305 HydrophobicContact CE1-CG 4.35Å; Y301-R305 HydrophobicContact CE2-CB 4.22Å; Y301-R305 VanDerWaalsContact O-CB 3.26Å; Y301-R305 WeakPolarHBondContact O-CB 3.29Å; Y301-R305 PolarHBondContact O-N 3.12Å; R305-N308 PolarHBondContact O-N 2.86Å; R305-S309 WeakPolarHBondContact CD-OG 3.5Å; R305-S309 VanDerWaalsContact O-CB 3.24Å; R305-S309 WeakPolarHBondContact O-CB 3.31Å; R305-S309 PolarHBondContact O-N 2.9Å; R305-S309 PolarHBondContact O-OG 2.88Å; R305-S309 VanDerWaalsContact O-OG 3.07Å
306G96.4Very high94.9Very high19 Ų1947 Ų4720%0.19623%0.226CC..Hα-helixtrans-57.8-50.5175.600000112.3Y302 Q310Y302-G306 WeakPolarHBondContact O-CA 3.44Å; Y302-G306 PolarHBondContact O-N 3.11Å; G306-Q310 WeakPolarHBondContact O-CB 3.47Å; G306-Q310 PolarHBondContact O-N 3.04Å
307A96Very high94.5Very high0 Ų048 Ų480%023%0.232CC..Hα-helixtrans-61.6-47.217800000112.9I303 Q310 K311 W342 W343 P349 N350I303-A307 WeakPolarHBondContact O-CB 3.49Å; I303-A307 PolarHBondContact O-N 3.45Å; A307-Q310 PolarHBondContact O-N 3.21Å; A307-K311 PolarHBondContact O-N 3.42Å; A307-W342 HydrophobicContact CB-CB 3.96Å; A307-W342 HydrophobicContact CB-CG 4.1Å; A307-W343 HydrophobicContact CB-CZ2 4.49Å; A307-W343 PolarHBondContact O-NE1 3.22Å; A307-W343 VanDerWaalsContact O-NE1 3.08Å; A307-P349 HydrophobicContact CB-CB 3.99Å; A307-P349 HydrophobicContact CB-CG 3.67Å; A307-N350 HydrophobicContact CB-CB 4.26Å
308N94.6Very high94Very high18 Ų1850.7 Ų50.710%0.09625%0.251CS..Hα-helixtrans-66.5-43-179.9-82.9-50.1000112.1F304 R305 Q310 K311 N312F304-N308 VanDerWaalsContact CE2-ND2 3.3Å; F304-N308 WeakPolarHBondContact CE2-ND2 3.18Å; F304-N308 WeakPolarHBondContact CZ-ND2 3.44Å; F304-N308 WeakPolarHBondContact O-CB 3.1Å; F304-N308 PolarHBondContact O-N 2.95Å; F304-N308 VanDerWaalsContact O-N 3.1Å; F304-N308 PolarHBondContact O-ND2 2.91Å; F304-N308 VanDerWaalsContact O-ND2 3.09Å; R305-N308 PolarHBondContact O-N 2.86Å; N308-Q310 VanDerWaalsContact C-N 3.35Å; N308-Q310 PolarHBondContact O-N 3.44Å; N308-K311 PolarHBondContact O-N 3.31Å; N308-K311 PolarHBondContact OD1-NZ 3Å; N308-K311 VanDerWaalsContact OD1-NZ 3.14Å; N308-N312 VanDerWaalsContact O-CB 3.26Å; N308-N312 WeakPolarHBondContact O-CB 3.37Å; N308-N312 PolarHBondContact O-N 3.43Å; N308-N312 PolarHBondContact O-ND2 2.92Å
309S93.6Very high93.6Very high43 Ų4352.9 Ų52.930%0.30126%0.263SS..Hα-helixtrans-62.7-41.2175.4-69.30000111.8R305 N312 T313R305-S309 WeakPolarHBondContact CD-OG 3.5Å; R305-S309 VanDerWaalsContact O-CB 3.24Å; R305-S309 WeakPolarHBondContact O-CB 3.31Å; R305-S309 PolarHBondContact O-N 2.9Å; R305-S309 PolarHBondContact O-OG 2.88Å; R305-S309 VanDerWaalsContact O-OG 3.07Å; S309-N312 PolarHBondContact O-N 3.14Å; S309-T313 WeakPolarHBondContact O-CB 3.32Å; S309-T313 PolarHBondContact O-N 2.88Å; S309-T313 PolarHBondContact O-OG1 2.7Å
310Q95.1Very high93.3Very high30 Ų3050.4 Ų50.414%0.1425%0.25CS..Hα-helixtrans-60-48.6175.4-175.4173.566.600111.6G306 A307 N308 F314 V323 L326 L338G306-Q310 WeakPolarHBondContact O-CB 3.47Å; G306-Q310 PolarHBondContact O-N 3.04Å; A307-Q310 PolarHBondContact O-N 3.21Å; N308-Q310 VanDerWaalsContact C-N 3.35Å; N308-Q310 PolarHBondContact O-N 3.44Å; Q310-F314 VanDerWaalsContact O-CB 3.26Å; Q310-F314 WeakPolarHBondContact O-CB 3.38Å; Q310-F314 PolarHBondContact O-N 2.97Å; Q310-V323 HydrophobicContact CG-CG1 4.3Å; Q310-L326 HydrophobicContact CG-CD1 3.74Å; Q310-L338 HydrophobicContact CG-CD1 4.36Å
311K92Very high93.1Very high35 Ų3556.1 Ų56.115%0.15229%0.288CS..Hα-helixtrans-60.8-45.6176177.8-178.262.8-170.10112.1A307 N308 F314 R315 W343A307-K311 PolarHBondContact O-N 3.42Å; N308-K311 PolarHBondContact O-N 3.31Å; N308-K311 PolarHBondContact OD1-NZ 3Å; N308-K311 VanDerWaalsContact OD1-NZ 3.14Å; K311-F314 PolarHBondContact O-N 2.92Å; K311-R315 WeakPolarHBondContact O-CB 3.09Å; K311-R315 WeakPolarHBondContact O-CG 3.43Å; K311-R315 PolarHBondContact O-N 3.3Å; K311-W343 HydrophobicContact CB-CZ2 3.67Å; K311-W343 HydrophobicContact CD-CH2 3.81Å; K311-W343 HydrophobicContact CD-CZ2 3.6Å; K311-W343 HydrophobicContact CG-CZ2 4.11Å
312N89.4Confident92.7Very high30 Ų3061.9 Ų61.916%0.1631%0.309CS..Hα-helixtrans-68.6-45-175.8-71.1-13000111.7N308 S309 F314 R315 K316N308-N312 VanDerWaalsContact O-CB 3.26Å; N308-N312 WeakPolarHBondContact O-CB 3.37Å; N308-N312 PolarHBondContact O-N 3.43Å; N308-N312 PolarHBondContact O-ND2 2.92Å; S309-N312 PolarHBondContact O-N 3.14Å; N312-F314 VanDerWaalsContact C-N 3.35Å; N312-R315 PolarHBondContact O-N 3.24Å; N312-K316 WeakPolarHBondContact O-CB 3.48Å; N312-K316 WeakPolarHBondContact O-CG 3.21Å; N312-K316 PolarHBondContact O-N 3.13Å
313T91.6Very high92.5Very high27 Ų2754.7 Ų54.717%0.16628%0.281CS..Hα-helixtrans-60-46.7174.2-62.50000110.5S309 R315 K316 N317 D320 V323S309-T313 WeakPolarHBondContact O-CB 3.32Å; S309-T313 PolarHBondContact O-N 2.88Å; S309-T313 PolarHBondContact O-OG1 2.7Å; T313-R315 PolarHBondContact O-N 3.03Å; T313-K316 PolarHBondContact O-N 2.94Å; T313-N317 CarbonylContact O-C 3.54Å; T313-N317 PolarHBondContact O-N 3.37Å; T313-D320 HydrophobicContact CG2-CB 3.77Å; T313-V323 HydrophobicContact CG2-CG1 4Å; T313-V323 HydrophobicContact CG2-CG2 4.1Å
314F92.2Very high92.1Very high19 Ų1956.6 Ų56.68%0.08330%0.3CS..Hα-helixtrans-60.3-43.7178178-102.8000113.3Q310 K311 N312 K316 P318 V323 T328 K336 L338Q310-F314 VanDerWaalsContact O-CB 3.26Å; Q310-F314 WeakPolarHBondContact O-CB 3.38Å; Q310-F314 PolarHBondContact O-N 2.97Å; K311-F314 PolarHBondContact O-N 2.92Å; N312-F314 VanDerWaalsContact C-N 3.35Å; F314-K316 VanDerWaalsContact C-N 3.34Å; F314-K316 PolarHBondContact O-N 3.39Å; F314-P318 HydrophobicContact CD2-CB 4.42Å; F314-P318 HydrophobicContact CE2-CB 4.28Å; F314-P318 WeakPolarHBondContact O-CD 3.44Å; F314-P318 VanDerWaalsContact O-CG 3.31Å; F314-P318 WeakPolarHBondContact O-CG 3.37Å; F314-V323 HydrophobicContact CB-CB 4.35Å; F314-V323 HydrophobicContact CB-CG1 4.38Å; F314-V323 HydrophobicContact CB-CG2 4.31Å; F314-V323 HydrophobicContact CD2-CB 4.41Å; F314-V323 HydrophobicContact CD2-CG2 4.32Å; F314-T328 HydrophobicContact CE2-CG2 3.64Å; F314-T328 HydrophobicContact CZ-CG2 3.58Å; F314-K336 HydrophobicContact CE1-CB 4.24Å; F314-K336 WeakPolarHBondContact CE1-O 3.31Å; F314-K336 HydrophobicContact CZ-CB 3.68Å; F314-L338 HydrophobicContact CB-CD1 3.81Å; F314-L338 HydrophobicContact CB-CD2 4.44Å; F314-L338 HydrophobicContact CB-CG 4.37Å; F314-L338 HydrophobicContact CD1-CD1 3.83Å; F314-L338 HydrophobicContact CD1-CD2 4.15Å; F314-L338 HydrophobicContact CD1-CG 3.68Å; F314-L338 HydrophobicContact CD2-CD1 4.44Å; F314-L338 HydrophobicContact CD2-CD2 3.64Å; F314-L338 HydrophobicContact CD2-CG 4.12Å; F314-L338 HydrophobicContact CE1-CD2 4.27Å; F314-L338 HydrophobicContact CE1-CG 3.87Å; F314-L338 HydrophobicContact CE2-CD2 3.77Å; F314-L338 HydrophobicContact CE2-CG 4.29Å; F314-L338 HydrophobicContact CG-CD1 3.77Å; F314-L338 HydrophobicContact CG-CD2 3.81Å; F314-L338 HydrophobicContact CG-CG 3.79Å; F314-L338 HydrophobicContact CZ-CD2 4.07Å; F314-L338 HydrophobicContact CZ-CG 4.16Å
315R85.9Confident91.8Very high146 Ų14659.3 Ų59.355%0.55133%0.333SS*.Hα-helixtrans-68.1-32.2178.4-74.5178.2176.3-175.5-2113K311 N312 T313K311-R315 WeakPolarHBondContact O-CB 3.09Å; K311-R315 WeakPolarHBondContact O-CG 3.43Å; K311-R315 PolarHBondContact O-N 3.3Å; N312-R315 PolarHBondContact O-N 3.24Å; T313-R315 PolarHBondContact O-N 3.03Å
316K86Confident91.7Very high142 Ų14259.5 Ų59.562%0.61734%0.337SS*.Hα-helixtrans-81.9-45-179.9-74-176.9173.3-165.90112.6E242 N312 T313 F314E242-K316 VanDerWaalsContact OE1-CE 3.3Å; E242-K316 WeakPolarHBondContact OE1-CE 3.19Å; E242-K316 IonicContact OE1-NZ 2.97Å; E242-K316 PolarHBondContact OE1-NZ 2.62Å; E242-K316 IonicContact OE2-NZ 3.79Å; N312-K316 WeakPolarHBondContact O-CB 3.48Å; N312-K316 WeakPolarHBondContact O-CG 3.21Å; N312-K316 PolarHBondContact O-N 3.13Å; T313-K316 PolarHBondContact O-N 2.94Å; F314-K316 VanDerWaalsContact C-N 3.34Å; F314-K316 PolarHBondContact O-N 3.39Å
317N89Confident91.7Very high75 Ų7564.3 Ų64.340%0.40135%0.354SS..  trans-146.592.3-179.3-177.58.6000110.2T313 S319 D320T313-N317 CarbonylContact O-C 3.54Å; T313-N317 PolarHBondContact O-N 3.37Å; N317-S319 PolarHBondContact O-N 2.87Å; N317-S319 VanDerWaalsContact O-N 3.13Å; N317-S319 PolarHBondContact OD1-N 3.49Å; N317-S319 VanDerWaalsContact OD1-N 3.13Å; N317-D320 HydrophobicContact CB-CB 4.29Å; N317-D320 WeakPolarHBondContact O-CB 3.38Å; N317-D320 PolarHBondContact O-N 3.3Å; N317-D320 VanDerWaalsContact O-N 3.1Å
318P88.3Confident91.6Very high66 Ų6666.4 Ų66.443%0.42937%0.367SS..THydrogen-bonded Turntrans-60.6-20.4177.2-22.131.1000114.3F314F314-P318 HydrophobicContact CD2-CB 4.42Å; F314-P318 HydrophobicContact CE2-CB 4.28Å; F314-P318 WeakPolarHBondContact O-CD 3.44Å; F314-P318 VanDerWaalsContact O-CG 3.31Å; F314-P318 WeakPolarHBondContact O-CG 3.37Å
319S90.4Very high91.7Very high97 Ų9766.4 Ų66.468%0.67837%0.367SS*.THydrogen-bonded Turntrans-89.70.7179.8-53.90000113.3N317N317-S319 PolarHBondContact O-N 2.87Å; N317-S319 VanDerWaalsContact O-N 3.13Å; N317-S319 PolarHBondContact OD1-N 3.49Å; N317-S319 VanDerWaalsContact OD1-N 3.13Å
320D92.6Very high91.6Very high25 Ų2568.6 Ų68.613%0.13438%0.382CS..SBendtrans-61.6130.3176.2-176.2-58.7000109.8T313 N317 R322 V323 A324T313-D320 HydrophobicContact CG2-CB 3.77Å; N317-D320 HydrophobicContact CB-CB 4.29Å; N317-D320 WeakPolarHBondContact O-CB 3.38Å; N317-D320 PolarHBondContact O-N 3.3Å; N317-D320 VanDerWaalsContact O-N 3.1Å; D320-R322 PolarHBondContact O-N 3.03Å; D320-R322 VanDerWaalsContact OD1-CB 3.27Å; D320-R322 WeakPolarHBondContact OD1-CB 3.37Å; D320-R322 WeakPolarHBondContact OD1-CG 3.42Å; D320-R322 IonicContact OD1-CZ 2.74Å; D320-R322 PolarHBondContact OD1-N 3.48Å; D320-R322 IonicContact OD1-NE 3.92Å; D320-R322 PolarHBondContact OD1-NE 2.91Å; D320-R322 IonicContact OD1-NH2 3.17Å; D320-R322 IonicContact OD2-CZ 2.78Å; D320-R322 IonicContact OD2-NE 3.76Å; D320-R322 PolarHBondContact OD2-NE 2.9Å; D320-R322 IonicContact OD2-NH2 2.92Å; D320-R322 PolarHBondContact OD2-NH2 3.5Å; D320-V323 HydrophobicContact CB-CG2 4.06Å; D320-V323 WeakPolarHBondContact O-CG2 3.5Å; D320-V323 PolarHBondContact O-N 2.8Å; D320-A324 WeakPolarHBondContact O-CB 3.46Å; D320-A324 PolarHBondContact O-N 2.91Å
321P92.9Very high91.5Very high121 Ų12167.8 Ų67.879%0.78638%0.379SS*.Hα-helixtrans-53.4-27.2-176-28.434.9000114.6V323P321-V323 PolarHBondContact O-N 3.13Å
322R91.6Very high91.2Very high180 Ų18071.5 Ų71.568%0.67942%0.416SS*.Hα-helixtrans-69.6-20179.1-62.9173.5-70.8-179.7-2.7113.6D320D320-R322 PolarHBondContact O-N 3.03Å; D320-R322 VanDerWaalsContact OD1-CB 3.27Å; D320-R322 WeakPolarHBondContact OD1-CB 3.37Å; D320-R322 WeakPolarHBondContact OD1-CG 3.42Å; D320-R322 IonicContact OD1-CZ 2.74Å; D320-R322 PolarHBondContact OD1-N 3.48Å; D320-R322 IonicContact OD1-NE 3.92Å; D320-R322 PolarHBondContact OD1-NE 2.91Å; D320-R322 IonicContact OD1-NH2 3.17Å; D320-R322 IonicContact OD2-CZ 2.78Å; D320-R322 IonicContact OD2-NE 3.76Å; D320-R322 PolarHBondContact OD2-NE 2.9Å; D320-R322 IonicContact OD2-NH2 2.92Å; D320-R322 PolarHBondContact OD2-NH2 3.5Å
323V93.4Very high90.9Very high4 Ų473.2 Ų73.22%0.02443%0.428CS..Hα-helixtrans-129.5-12.7-176.3-59.80000113.5Q310 T313 F314 D320 P321 G325 L326Q310-V323 HydrophobicContact CG-CG1 4.3Å; T313-V323 HydrophobicContact CG2-CG1 4Å; T313-V323 HydrophobicContact CG2-CG2 4.1Å; F314-V323 HydrophobicContact CB-CB 4.35Å; F314-V323 HydrophobicContact CB-CG1 4.38Å; F314-V323 HydrophobicContact CB-CG2 4.31Å; F314-V323 HydrophobicContact CD2-CB 4.41Å; F314-V323 HydrophobicContact CD2-CG2 4.32Å; D320-V323 HydrophobicContact CB-CG2 4.06Å; D320-V323 WeakPolarHBondContact O-CG2 3.5Å; D320-V323 PolarHBondContact O-N 2.8Å; P321-V323 PolarHBondContact O-N 3.13Å; V323-G325 PolarHBondContact O-N 2.92Å; V323-L326 HydrophobicContact CB-CD1 3.83Å; V323-L326 HydrophobicContact CB-CG 4.49Å; V323-L326 HydrophobicContact CG1-CD1 3.97Å; V323-L326 VanDerWaalsContact O-CB 3.27Å; V323-L326 WeakPolarHBondContact O-CB 3.37Å; V323-L326 WeakPolarHBondContact O-CG 3.28Å; V323-L326 PolarHBondContact O-N 3.21Å
324A89.6Confident90.5Very high60 Ų6075.4 Ų75.450%0.49646%0.456SS..Hα-helixtrans-61.3-31-17700000113.5D320 L326D320-A324 WeakPolarHBondContact O-CB 3.46Å; D320-A324 PolarHBondContact O-N 2.91Å; A324-L326 VanDerWaalsContact C-N 3.3Å
325G91.3Very high90.2Very high77 Ų7780.2 Ų80.279%0.79447%0.473SS*.THydrogen-bonded Turntrans-82.1-0.4176.200000114.8V323V323-G325 PolarHBondContact O-N 2.92Å
326L93.9Very high90.4Very high36 Ų3678.6 Ų78.619%0.18847%0.47CS..SBendtrans-78.7134.8-179.8-62.5175.6000110.8Q310 V323 A324 L338 S340Q310-L326 HydrophobicContact CG-CD1 3.74Å; V323-L326 HydrophobicContact CB-CD1 3.83Å; V323-L326 HydrophobicContact CB-CG 4.49Å; V323-L326 HydrophobicContact CG1-CD1 3.97Å; V323-L326 VanDerWaalsContact O-CB 3.27Å; V323-L326 WeakPolarHBondContact O-CB 3.37Å; V323-L326 WeakPolarHBondContact O-CG 3.28Å; V323-L326 PolarHBondContact O-N 3.21Å; A324-L326 VanDerWaalsContact C-N 3.3Å; L326-L338 HydrophobicContact CB-CD2 3.81Å; L326-L338 HydrophobicContact CD1-CD2 3.74Å; L326-L338 HydrophobicContact CG-CD2 4.44Å; L326-S340 WeakPolarHBondContact CA-OG 3.35Å; L326-S340 WeakPolarHBondContact CB-OG 3.23Å
327E95.5Very high90.7Very high119 Ų11972.8 Ų72.856%0.55645%0.446SS*.  trans-63.5141170.8-62.7-170.8-174.800111.4V339 S340 R408E327-V339 HydrophobicContact CB-CG2 3.76Å; E327-V339 PolarHBondContact O-N 3.44Å; E327-S340 PolarHBondContact N-OG 2.97Å; E327-S340 PolarHBondContact O-OG 3.32Å; E327-R408 IonicContact OE2-NH1 3.71Å
328T95.5Very high91Very high44 Ų4469.9 Ų69.927%0.2743%0.43SS..EExtended strand (participates in β ladder)trans-138.7156.5-179.458.80000112.4F314 K336 L337 L338F314-T328 HydrophobicContact CE2-CG2 3.64Å; F314-T328 HydrophobicContact CZ-CG2 3.58Å; T328-K336 HydrophobicContact CG2-CB 4.41Å; T328-L337 CarbonylContact C-O 3.33Å; T328-L337 WeakPolarHBondContact CA-O 3.34Å; T328-L337 VanDerWaalsContact CB-O 3.29Å; T328-L337 WeakPolarHBondContact CB-O 3.29Å; T328-L338 HydrophobicContact CG2-CD2 4.02Å
329I94.8Very high91.3Very high19 Ų1967.2 Ų67.210%0.09741%0.413CS..EExtended strand (participates in β ladder)trans-106.7124.7166.8-63.8169.3000108.2K336 L337 V339 A401 E404I329-K336 CarbonylContact O-C 3.12Å; I329-K336 WeakPolarHBondContact O-CA 3.22Å; I329-L337 HydrophobicContact CB-CB 4.41Å; I329-L337 PolarHBondContact N-O 3.17Å; I329-L337 PolarHBondContact O-N 3.42Å; I329-V339 HydrophobicContact CB-CG1 4.32Å; I329-V339 HydrophobicContact CD1-CG1 3.54Å; I329-V339 HydrophobicContact CG1-CG1 3.6Å; I329-V339 HydrophobicContact CG1-CG2 4.46Å; I329-A401 HydrophobicContact CG2-CB 3.87Å; I329-E404 HydrophobicContact CD1-CB 4.17Å; I329-E404 HydrophobicContact CD1-CG 3.73Å
330S93Very high91.5Very high88 Ų8863.8 Ų63.862%0.61539%0.388SS*.EExtended strand (participates in β ladder)trans-73.5136.3171.5-65.60000110.3
331T91.7Very high91.6Very high13 Ų1364.7 Ų64.78%0.0840%0.404CS..  trans-107.6157.617873.60000110.9T333 G334 R335 L337 Y398 A401T331-T333 PolarHBondContact O-N 2.91Å; T331-T333 VanDerWaalsContact O-N 3.12Å; T331-T333 PolarHBondContact OG1-N 3.38Å; T331-T333 PolarHBondContact OG1-OG1 3.49Å; T331-G334 PolarHBondContact O-N 3.09Å; T331-R335 WeakPolarHBondContact CB-O 3.33Å; T331-R335 WeakPolarHBondContact CG2-O 3.44Å; T331-R335 PolarHBondContact N-O 2.96Å; T331-R335 PolarHBondContact OG1-N 2.93Å; T331-R335 PolarHBondContact OG1-O 3.37Å; T331-L337 HydrophobicContact CG2-CD1 3.91Å; T331-L337 HydrophobicContact CG2-CD2 4.3Å; T331-L337 HydrophobicContact CG2-CG 3.68Å; T331-Y398 HydrophobicContact CG2-CD1 3.62Å; T331-Y398 HydrophobicContact CG2-CE1 4.17Å; T331-Y398 HydrophobicContact CG2-CG 4.08Å; T331-A401 HydrophobicContact CG2-CB 3.96Å
332A86.6Confident91.7Very high113 Ų11361.6 Ų61.693%0.93438%0.377SS*.THydrogen-bonded Turntrans-60.1-19.8173.100000113.5G334A332-G334 PolarHBondContact O-N 3.23Å
333T83.2Confident91.9Very high67 Ų6754.1 Ų54.141%0.41135%0.349SS..THydrogen-bonded Turntrans-77.7-0.3176.271.40000113.6T331 R335 K397 Y398T331-T333 PolarHBondContact O-N 2.91Å; T331-T333 VanDerWaalsContact O-N 3.12Å; T331-T333 PolarHBondContact OG1-N 3.38Å; T331-T333 PolarHBondContact OG1-OG1 3.49Å; T333-R335 PolarHBondContact O-N 3.14Å; T333-R335 PolarHBondContact OG1-N 3.37Å; T333-K397 HydrophobicContact CG2-CG 4.45Å; T333-Y398 HydrophobicContact CG2-CD1 4.09Å; T333-Y398 HydrophobicContact CG2-CE1 4.26Å
334G83.8Confident92Very high72 Ų7255 Ų5574%0.74236%0.359SS*.SBendtrans77.3-7.2-172.800000114.1T331 A332T331-G334 PolarHBondContact O-N 3.09Å; A332-G334 PolarHBondContact O-N 3.23Å
335R85.5Confident92.2Very high120 Ų12056 Ų5645%0.45335%0.354SS..  trans-81158.9171.8-60.9-172.1179.8-161.9-0.7111.1T331 T333T331-R335 WeakPolarHBondContact CB-O 3.33Å; T331-R335 WeakPolarHBondContact CG2-O 3.44Å; T331-R335 PolarHBondContact N-O 2.96Å; T331-R335 PolarHBondContact OG1-N 2.93Å; T331-R335 PolarHBondContact OG1-O 3.37Å; T333-R335 PolarHBondContact O-N 3.14Å; T333-R335 PolarHBondContact OG1-N 3.37Å
336K90.2Very high92.5Very high113 Ų11352.3 Ų52.349%0.49132%0.316SS..EExtended strand (participates in β ladder)trans-114.2143.9175.4-68.7-178.6180-175.30110.5F314 T328 I329F314-K336 HydrophobicContact CE1-CB 4.24Å; F314-K336 WeakPolarHBondContact CE1-O 3.31Å; F314-K336 HydrophobicContact CZ-CB 3.68Å; T328-K336 HydrophobicContact CG2-CB 4.41Å; I329-K336 CarbonylContact O-C 3.12Å; I329-K336 WeakPolarHBondContact O-CA 3.22Å
337L92.7Very high92.6Very high20 Ų2051.2 Ų51.211%0.10531%0.31CS..EExtended strand (participates in β ladder)trans-102.8131.4174.3-57.7176.1000109T328 I329 T331 Y398 W402T328-L337 CarbonylContact C-O 3.33Å; T328-L337 WeakPolarHBondContact CA-O 3.34Å; T328-L337 VanDerWaalsContact CB-O 3.29Å; T328-L337 WeakPolarHBondContact CB-O 3.29Å; I329-L337 HydrophobicContact CB-CB 4.41Å; I329-L337 PolarHBondContact N-O 3.17Å; I329-L337 PolarHBondContact O-N 3.42Å; T331-L337 HydrophobicContact CG2-CD1 3.91Å; T331-L337 HydrophobicContact CG2-CD2 4.3Å; T331-L337 HydrophobicContact CG2-CG 3.68Å; L337-Y398 HydrophobicContact CD1-CD2 4.41Å; L337-Y398 HydrophobicContact CD2-CD2 4.08Å; L337-Y398 HydrophobicContact CD2-CE2 3.86Å; L337-W402 HydrophobicContact CD1-CE3 3.93Å; L337-W402 HydrophobicContact CD1-CZ3 4.47Å
338L93.8Very high92.6Very high13 Ų1345.8 Ų45.87%0.06828%0.284CS..EExtended strand (participates in β ladder)trans-74.8129.9173.8-76.5170.8000109.7Q310 F314 L326 T328 W343 Y405Q310-L338 HydrophobicContact CG-CD1 4.36Å; F314-L338 HydrophobicContact CB-CD1 3.81Å; F314-L338 HydrophobicContact CB-CD2 4.44Å; F314-L338 HydrophobicContact CB-CG 4.37Å; F314-L338 HydrophobicContact CD1-CD1 3.83Å; F314-L338 HydrophobicContact CD1-CD2 4.15Å; F314-L338 HydrophobicContact CD1-CG 3.68Å; F314-L338 HydrophobicContact CD2-CD1 4.44Å; F314-L338 HydrophobicContact CD2-CD2 3.64Å; F314-L338 HydrophobicContact CD2-CG 4.12Å; F314-L338 HydrophobicContact CE1-CD2 4.27Å; F314-L338 HydrophobicContact CE1-CG 3.87Å; F314-L338 HydrophobicContact CE2-CD2 3.77Å; F314-L338 HydrophobicContact CE2-CG 4.29Å; F314-L338 HydrophobicContact CG-CD1 3.77Å; F314-L338 HydrophobicContact CG-CD2 3.81Å; F314-L338 HydrophobicContact CG-CG 3.79Å; F314-L338 HydrophobicContact CZ-CD2 4.07Å; F314-L338 HydrophobicContact CZ-CG 4.16Å; L326-L338 HydrophobicContact CB-CD2 3.81Å; L326-L338 HydrophobicContact CD1-CD2 3.74Å; L326-L338 HydrophobicContact CG-CD2 4.44Å; T328-L338 HydrophobicContact CG2-CD2 4.02Å; L338-W343 HydrophobicContact CB-CB 3.94Å; L338-W343 HydrophobicContact CB-CG 4.26Å; L338-W343 HydrophobicContact CD1-CG 4.43Å; L338-Y405 WeakPolarHBondContact O-CE2 3.33Å
339V95.3Very high92.7Very high11 Ų1143.7 Ų43.77%0.06727%0.272CS..  trans-126.713.6-179-48.80000113.5E327 I329 G344 Y405E327-V339 HydrophobicContact CB-CG2 3.76Å; E327-V339 PolarHBondContact O-N 3.44Å; I329-V339 HydrophobicContact CB-CG1 4.32Å; I329-V339 HydrophobicContact CD1-CG1 3.54Å; I329-V339 HydrophobicContact CG1-CG1 3.6Å; I329-V339 HydrophobicContact CG1-CG2 4.46Å; V339-G344 VanDerWaalsContact O-CA 3.25Å; V339-G344 WeakPolarHBondContact O-CA 3.46Å; V339-Y405 HydrophobicContact CB-CD2 4.15Å; V339-Y405 HydrophobicContact CB-CE2 4.28Å; V339-Y405 HydrophobicContact CG1-CD2 3.39Å; V339-Y405 HydrophobicContact CG1-CE2 3.83Å; V339-Y405 HydrophobicContact CG1-CG 4.49Å
340S94.5Very high92.7Very high24 Ų2443.4 Ų43.417%0.16827%0.27CS..SBendtrans-139.6175.7178.861.50000110.2L326 E327 G344L326-S340 WeakPolarHBondContact CA-OG 3.35Å; L326-S340 WeakPolarHBondContact CB-OG 3.23Å; E327-S340 PolarHBondContact N-OG 2.97Å; E327-S340 PolarHBondContact O-OG 3.32Å; S340-G344 PolarHBondContact O-N 3.34Å
341G94.6Very high92.9Very high45 Ų4540.2 Ų40.246%0.46425%0.245SC..THydrogen-bonded Turntrans66.6-139.8-17100000111.1W343 G344 M345G341-W343 VanDerWaalsContact C-N 3.29Å; G341-W343 PolarHBondContact O-N 2.93Å; G341-G344 PolarHBondContact O-N 3.44Å; G341-M345 PolarHBondContact O-N 3.46Å
342W96.1Very high93.2Very high56 Ų5640.7 Ų40.721%0.21225%0.247CC..Hα-helixtrans-61.4-40.9178.6-64.9111000112Y302 I303 A307 G344 M345 P349Y302-W342 AromaticContact CD1-CH2 3.94Å; Y302-W342 HydrophobicContact CD1-CH2 3.94Å; Y302-W342 HydrophobicContact CD1-CZ2 4.07Å; Y302-W342 AromaticContact CE1-CH2 3.57Å; Y302-W342 HydrophobicContact CE1-CH2 3.57Å; Y302-W342 AromaticContact CE1-CZ2 3.51Å; Y302-W342 HydrophobicContact CE1-CZ2 3.51Å; Y302-W342 AromaticContact CZ-CZ2 4Å; I303-W342 HydrophobicContact CB-CZ3 4.38Å; I303-W342 HydrophobicContact CG1-CH2 4.02Å; I303-W342 HydrophobicContact CG1-CZ3 3.9Å; I303-W342 HydrophobicContact CG2-CE3 4.31Å; I303-W342 HydrophobicContact CG2-CZ3 4.18Å; A307-W342 HydrophobicContact CB-CB 3.96Å; A307-W342 HydrophobicContact CB-CG 4.1Å; W342-G344 PolarHBondContact O-N 2.81Å; W342-M345 HydrophobicContact CE3-CE 4.09Å; W342-M345 HydrophobicContact CZ3-CE 4.24Å; W342-M345 PolarHBondContact O-N 3.3Å; W342-P349 HydrophobicContact CB-CB 3.98Å; W342-P349 HydrophobicContact CB-CG 3.76Å
343W96.1Very high93.7Very high22 Ų2235.3 Ų35.38%0.08320%0.202CC..Hα-helixtrans-77.3-6.2-178.2-57.889.5000113.3A307 K311 L338 G341 R347 P349 N350 Y405A307-W343 HydrophobicContact CB-CZ2 4.49Å; A307-W343 PolarHBondContact O-NE1 3.22Å; A307-W343 VanDerWaalsContact O-NE1 3.08Å; K311-W343 HydrophobicContact CB-CZ2 3.67Å; K311-W343 HydrophobicContact CD-CH2 3.81Å; K311-W343 HydrophobicContact CD-CZ2 3.6Å; K311-W343 HydrophobicContact CG-CZ2 4.11Å; L338-W343 HydrophobicContact CB-CB 3.94Å; L338-W343 HydrophobicContact CB-CG 4.26Å; L338-W343 HydrophobicContact CD1-CG 4.43Å; G341-W343 VanDerWaalsContact C-N 3.29Å; G341-W343 PolarHBondContact O-N 2.93Å; W343-R347 WeakPolarHBondContact CZ3-O 3.43Å; W343-P349 HydrophobicContact CD2-CG 4.12Å; W343-P349 HydrophobicContact CE3-CG 4.32Å; W343-P349 HydrophobicContact CG-CG 4.48Å; W343-P349 HydrophobicContact CZ2-CG 4.46Å; W343-N350 WeakPolarHBondContact CH2-OD1 3.3Å; W343-Y405 PolarHBondContact O-OH 3.15Å; W343-Y405 VanDerWaalsContact O-OH 3.1Å
344G94.7Very high94.3Very high24 Ų2432.7 Ų32.725%0.24719%0.186CC..Hα-helixtrans-91.7-18.9169.100000114V339 S340 G341 W342V339-G344 VanDerWaalsContact O-CA 3.25Å; V339-G344 WeakPolarHBondContact O-CA 3.46Å; S340-G344 PolarHBondContact O-N 3.34Å; G341-G344 PolarHBondContact O-N 3.44Å; W342-G344 PolarHBondContact O-N 2.81Å
345M93.9Very high95Very high79 Ų7930.4 Ų30.439%0.38916%0.156SC..Hα-helixtrans-81.6-46.6-178.7-175.7177.967.300111.6G341 W342G341-M345 PolarHBondContact O-N 3.46Å; W342-M345 HydrophobicContact CE3-CE 4.09Å; W342-M345 HydrophobicContact CZ3-CE 4.24Å; W342-M345 PolarHBondContact O-N 3.3Å
346V96.3Very high95.6Very high0 Ų026.6 Ų26.60%014%0.144CC..  trans-146.9158.6175-64.10000108.2H348 P349 V409 Y411 P415V346-H348 VanDerWaalsContact C-N 3.33Å; V346-H348 PolarHBondContact O-N 3.2Å; V346-P349 HydrophobicContact CG2-CB 3.76Å; V346-P349 HydrophobicContact CG2-CG 4.47Å; V346-P349 WeakPolarHBondContact O-CD 3.43Å; V346-V409 VanDerWaalsContact C-CG1 3.46Å; V346-Y411 CarbonylContact C-O 3.44Å; V346-Y411 WeakPolarHBondContact CA-O 3.43Å; V346-P415 HydrophobicContact CG1-CB 3.79Å; V346-P415 HydrophobicContact CG1-CG 4.28Å
347R96.1Very high96Very high13 Ų1321.3 Ų21.35%0.04912%0.122CC..SBendtrans-70.6-27.6-178.6-63.3-160.5-71.2-93.612.5113.5W343 E391 Y405 V409 P410 Y411 R412W343-R347 WeakPolarHBondContact CZ3-O 3.43Å; R347-E391 IonicContact CZ-OE2 3.78Å; R347-E391 IonicContact NE-OE2 2.72Å; R347-E391 PolarHBondContact NE-OE2 3.48Å; R347-E391 IonicContact NH2-OE1 3.48Å; R347-E391 IonicContact NH2-OE2 3.76Å; R347-E391 PolarHBondContact NH2-OE2 2.87Å; R347-Y405 HydrophobicContact CB-CE1 4.12Å; R347-Y405 HydrophobicContact CG-CD1 4.37Å; R347-Y405 HydrophobicContact CG-CE1 3.65Å; R347-V409 HydrophobicContact CG-CB 4.11Å; R347-V409 HydrophobicContact CG-CG1 3.82Å; R347-V409 WeakPolarHBondContact CG-O 3.29Å; R347-V409 PolarHBondContact NH1-O 2.89Å; R347-P410 PolarHBondContact NH1-O 3.42Å; R347-Y411 PolarHBondContact N-O 3.31Å; R347-R412 PolarHBondContact N-O 2.93Å; R347-R412 VanDerWaalsContact NH2-CG 3.27Å
348H96.1Very high96.3Very high6 Ų620.4 Ų20.43%0.02812%0.117CC..  trans-13067.9179.7-65.9-79.4000113V346 N350 Y351 L352 E387 D390 R412 I413V346-H348 VanDerWaalsContact C-N 3.33Å; V346-H348 PolarHBondContact O-N 3.2Å; H348-N350 PolarHBondContact O-N 3.2Å; H348-Y351 HydrophobicContact CB-CD2 3.37Å; H348-Y351 HydrophobicContact CB-CE2 3.95Å; H348-Y351 HydrophobicContact CB-CG 3.76Å; H348-Y351 AromaticContact CE1-CE2 3.96Å; H348-Y351 AromaticContact CG-CD2 3.57Å; H348-Y351 AromaticContact CG-CE2 3.6Å; H348-Y351 AromaticContact ND1-CD2 3.78Å; H348-Y351 AromaticContact ND1-CE2 3.37Å; H348-Y351 WeakPolarHBondContact ND1-CE2 3.3Å; H348-Y351 AromaticContact ND1-CZ 3.79Å; H348-Y351 WeakPolarHBondContact O-CB 3.23Å; H348-Y351 PolarHBondContact O-N 2.87Å; H348-Y351 VanDerWaalsContact O-N 3.1Å; H348-L352 PolarHBondContact O-N 3.41Å; H348-E387 WeakPolarHBondContact CD2-CG 3.47Å; H348-D390 IonicContact CE1-OD2 3.21Å; H348-D390 PolarHBondContact CE1-OD2 3.45Å; H348-D390 VanDerWaalsContact CE1-OD2 3.23Å; H348-D390 IonicContact NE2-OD2 3.66Å; H348-R412 WeakPolarHBondContact CB-O 3.29Å; H348-R412 PolarHBondContact N-O 3.48Å; H348-I413 HydrophobicContact CB-CG1 4.32Å
349P97Very high96.5Very high0 Ų022.7 Ų22.70%013%0.129CC..Hα-helixtrans-65.6-29.3-17927.1-34.7000112.1I303 A307 W342 W343 V346 Y351 L352 G353I303-P349 VanDerWaalsContact CG2-O 3.25Å; I303-P349 WeakPolarHBondContact CG2-O 3.47Å; A307-P349 HydrophobicContact CB-CB 3.99Å; A307-P349 HydrophobicContact CB-CG 3.67Å; W342-P349 HydrophobicContact CB-CB 3.98Å; W342-P349 HydrophobicContact CB-CG 3.76Å; W343-P349 HydrophobicContact CD2-CG 4.12Å; W343-P349 HydrophobicContact CE3-CG 4.32Å; W343-P349 HydrophobicContact CG-CG 4.48Å; W343-P349 HydrophobicContact CZ2-CG 4.46Å; V346-P349 HydrophobicContact CG2-CB 3.76Å; V346-P349 HydrophobicContact CG2-CG 4.47Å; V346-P349 WeakPolarHBondContact O-CD 3.43Å; P349-Y351 VanDerWaalsContact C-N 3.34Å; P349-Y351 PolarHBondContact O-N 2.86Å; P349-L352 WeakPolarHBondContact O-CB 3.25Å; P349-L352 PolarHBondContact O-N 3.43Å; P349-G353 PolarHBondContact O-N 2.92Å; P349-G353 VanDerWaalsContact O-N 3.08Å
350N95.8Very high96.6Very high12 Ų1222.1 Ų22.16%0.06413%0.125CC..Hα-helixtrans-62.3-40.4173.359.6-53.8000111.9F304 A307 W343 H348 L352 G353 D354F304-N350 HydrophobicContact CD2-CB 4.22Å; F304-N350 WeakPolarHBondContact CD2-O 3.3Å; A307-N350 HydrophobicContact CB-CB 4.26Å; W343-N350 WeakPolarHBondContact CH2-OD1 3.3Å; H348-N350 PolarHBondContact O-N 3.2Å; N350-L352 VanDerWaalsContact C-N 3.31Å; N350-L352 PolarHBondContact O-N 2.69Å; N350-G353 PolarHBondContact O-N 3.1Å; N350-D354 WeakPolarHBondContact O-CB 3.39Å; N350-D354 PolarHBondContact O-N 3.14Å
351Y97Very high96.8Very high22 Ų2221.1 Ų21.19%0.08612%0.118CC..Hα-helixtrans-66-35.5176.8-64-9.5000111.7H348 P349 D354 L355 L383 E387 I413H348-Y351 HydrophobicContact CB-CD2 3.37Å; H348-Y351 HydrophobicContact CB-CE2 3.95Å; H348-Y351 HydrophobicContact CB-CG 3.76Å; H348-Y351 AromaticContact CE1-CE2 3.96Å; H348-Y351 AromaticContact CG-CD2 3.57Å; H348-Y351 AromaticContact CG-CE2 3.6Å; H348-Y351 AromaticContact ND1-CD2 3.78Å; H348-Y351 AromaticContact ND1-CE2 3.37Å; H348-Y351 WeakPolarHBondContact ND1-CE2 3.3Å; H348-Y351 AromaticContact ND1-CZ 3.79Å; H348-Y351 WeakPolarHBondContact O-CB 3.23Å; H348-Y351 PolarHBondContact O-N 2.87Å; H348-Y351 VanDerWaalsContact O-N 3.1Å; P349-Y351 VanDerWaalsContact C-N 3.34Å; P349-Y351 PolarHBondContact O-N 2.86Å; Y351-D354 WeakPolarHBondContact O-CB 3.42Å; Y351-D354 PolarHBondContact O-N 2.85Å; Y351-L355 WeakPolarHBondContact O-CG 3.39Å; Y351-L355 PolarHBondContact O-N 3.14Å; Y351-L383 HydrophobicContact CD1-CD2 3.68Å; Y351-L383 HydrophobicContact CD2-CB 4.46Å; Y351-L383 HydrophobicContact CD2-CD2 4.24Å; Y351-L383 HydrophobicContact CE1-CD2 4Å; Y351-L383 HydrophobicContact CG-CD1 4.46Å; Y351-L383 HydrophobicContact CG-CD2 3.84Å; Y351-L383 HydrophobicContact CG-CG 4.5Å; Y351-E387 HydrophobicContact CD2-CB 4.39Å; Y351-E387 HydrophobicContact CE2-CB 4.14Å; Y351-I413 HydrophobicContact CD2-CD1 4.29Å; Y351-I413 HydrophobicContact CD2-CG1 4.43Å
352L97.4Very high96.9Very high23 Ų2319 Ų1912%0.1210%0.096CC..Hα-helixtrans-61.7-48.2172.9178.262.5000111.8H348 P349 N350 D354 L355 I356 I413 V414H348-L352 PolarHBondContact O-N 3.41Å; P349-L352 WeakPolarHBondContact O-CB 3.25Å; P349-L352 PolarHBondContact O-N 3.43Å; N350-L352 VanDerWaalsContact C-N 3.31Å; N350-L352 PolarHBondContact O-N 2.69Å; L352-D354 VanDerWaalsContact C-N 3.29Å; L352-D354 PolarHBondContact O-N 2.94Å; L352-L355 PolarHBondContact O-N 3.21Å; L352-I356 HydrophobicContact CD1-CD1 4.26Å; L352-I356 HydrophobicContact CG-CD1 4.12Å; L352-I356 WeakPolarHBondContact O-CG1 3.3Å; L352-I356 PolarHBondContact O-N 3.42Å; L352-I356 VanDerWaalsContact O-N 3.08Å; L352-I413 HydrophobicContact CB-CG2 4.34Å; L352-V414 HydrophobicContact CD1-CG2 4.29Å
353G97.6Very high97Very high0 Ų018.3 Ų18.30%010%0.096CC..Hα-helixtrans-59.2-41.617700000112.5G300 P349 N350 I356 M357G300-G353 WeakPolarHBondContact CA-O 3.46Å; G300-G353 VanDerWaalsContact O-CA 3.27Å; G300-G353 WeakPolarHBondContact O-CA 3.41Å; P349-G353 PolarHBondContact O-N 2.92Å; P349-G353 VanDerWaalsContact O-N 3.08Å; N350-G353 PolarHBondContact O-N 3.1Å; G353-I356 PolarHBondContact O-N 2.69Å; G353-M357 WeakPolarHBondContact O-CG 3.23Å; G353-M357 PolarHBondContact O-N 3.44Å
354D96.7Very high97.1Very high11 Ų1117.3 Ų17.36%0.0599%0.092CC..Hα-helixtrans-58.3-45.4174.1-91.3-21.8000113Y233 F304 N350 Y351 L352 I356 M357 A358 F379 L383Y233-D354 WeakPolarHBondContact CE2-OD1 3.24Å; F304-D354 HydrophobicContact CD2-CB 4.48Å; F304-D354 VanDerWaalsContact CD2-CG 3.45Å; F304-D354 WeakPolarHBondContact CD2-OD1 3.14Å; F304-D354 WeakPolarHBondContact CE2-OD1 3.08Å; F304-D354 VanDerWaalsContact CE2-OD2 3.3Å; F304-D354 WeakPolarHBondContact CE2-OD2 3.5Å; N350-D354 WeakPolarHBondContact O-CB 3.39Å; N350-D354 PolarHBondContact O-N 3.14Å; Y351-D354 WeakPolarHBondContact O-CB 3.42Å; Y351-D354 PolarHBondContact O-N 2.85Å; L352-D354 VanDerWaalsContact C-N 3.29Å; L352-D354 PolarHBondContact O-N 2.94Å; D354-I356 PolarHBondContact O-N 2.86Å; D354-M357 PolarHBondContact O-N 3.18Å; D354-M357 WeakPolarHBondContact OD1-CE 3.5Å; D354-A358 WeakPolarHBondContact O-CB 3.36Å; D354-A358 PolarHBondContact O-N 3.44Å; D354-F379 HydrophobicContact CB-CE1 3.8Å; D354-F379 HydrophobicContact CB-CZ 4.46Å; D354-L383 HydrophobicContact CB-CD1 4.25Å
355L97.8Very high97.3Very high24 Ų2416.1 Ų16.113%0.1268%0.081CC..Hα-helixtrans-65.8-37.5177-70.4178.1000113Y351 L352 A358 L359 L376 F379 T380 L383 I413Y351-L355 WeakPolarHBondContact O-CG 3.39Å; Y351-L355 PolarHBondContact O-N 3.14Å; L352-L355 PolarHBondContact O-N 3.21Å; L355-A358 PolarHBondContact O-N 3.08Å; L355-L359 PolarHBondContact O-N 3Å; L355-L376 HydrophobicContact CD2-CD1 4.31Å; L355-F379 HydrophobicContact CD2-CD1 4.37Å; L355-T380 VanDerWaalsContact CD2-OG1 3.27Å; L355-T380 WeakPolarHBondContact CD2-OG1 3.36Å; L355-L383 HydrophobicContact CD2-CD1 3.79Å; L355-L383 HydrophobicContact CG-CD1 3.84Å; L355-I413 HydrophobicContact CD1-CG2 4.11Å
356I98.3Very high97.3Very high40 Ų4013.3 Ų13.321%0.2057%0.072CC..Hα-helixtrans-65.7-42.2176.3-65.9167.7000110.3I296 I303 L352 G353 D354 L359 A360I296-I356 HydrophobicContact CG2-CG2 3.68Å; I296-I356 VanDerWaalsContact O-CG2 3.26Å; I296-I356 WeakPolarHBondContact O-CG2 3.41Å; I303-I356 HydrophobicContact CD1-CD1 3.9Å; L352-I356 HydrophobicContact CD1-CD1 4.26Å; L352-I356 HydrophobicContact CG-CD1 4.12Å; L352-I356 WeakPolarHBondContact O-CG1 3.3Å; L352-I356 PolarHBondContact O-N 3.42Å; L352-I356 VanDerWaalsContact O-N 3.08Å; G353-I356 PolarHBondContact O-N 2.69Å; D354-I356 PolarHBondContact O-N 2.86Å; I356-L359 PolarHBondContact O-N 3.1Å; I356-A360 PolarHBondContact O-N 3.39Å
357M98.4Very high97.2Very high3 Ų319.3 Ų19.32%0.01511%0.108CC..Hα-helixtrans-63.7-45.1173.5-70.9-173-6500111.3Y233 Y301 F304 G353 D354 L359 A360 W361Y233-M357 HydrophobicContact CD2-CE 3.86Å; Y233-M357 HydrophobicContact CD2-SD 4.32Å; Y233-M357 HydrophobicContact CE2-CE 3.92Å; Y301-M357 HydrophobicContact CD2-SD 4.09Å; F304-M357 HydrophobicContact CB-CE 3.75Å; F304-M357 HydrophobicContact CD1-CE 4.04Å; F304-M357 HydrophobicContact CD2-CE 4.14Å; F304-M357 HydrophobicContact CG-CE 3.72Å; G353-M357 WeakPolarHBondContact O-CG 3.23Å; G353-M357 PolarHBondContact O-N 3.44Å; D354-M357 PolarHBondContact O-N 3.18Å; D354-M357 WeakPolarHBondContact OD1-CE 3.5Å; M357-L359 VanDerWaalsContact C-N 3.26Å; M357-L359 PolarHBondContact O-N 3.35Å; M357-A360 CarbonylContact O-C 3.37Å; M357-A360 WeakPolarHBondContact O-CA 3.15Å; M357-A360 WeakPolarHBondContact O-CB 3.31Å; M357-A360 PolarHBondContact O-N 3.35Å; M357-W361 HydrophobicContact CB-CZ2 3.97Å; M357-W361 PolarHBondContact O-N 2.79Å; M357-W361 PolarHBondContact O-NE1 3.49Å
358A97.9Very high97Very high0 Ų022.6 Ų22.60%013%0.133CC..Hα-helixtrans-56.3-39.6177.400000113D354 L355 S362 Y375 L376 F379D354-A358 WeakPolarHBondContact O-CB 3.36Å; D354-A358 PolarHBondContact O-N 3.44Å; L355-A358 PolarHBondContact O-N 3.08Å; A358-S362 PolarHBondContact O-N 3.31Å; A358-S362 PolarHBondContact O-OG 2.95Å; A358-Y375 HydrophobicContact CB-CD1 3.74Å; A358-Y375 HydrophobicContact CB-CE1 3.37Å; A358-L376 HydrophobicContact CB-CD1 3.87Å; A358-F379 HydrophobicContact CB-CD1 4.28Å
359L98.3Very high96.9Very high61 Ų6124.8 Ų24.832%0.31914%0.143SC..Hα-helixtrans-64.1-49.7171.8175.862.2000110.8L355 I356 M357 W361 S362 L363 Y373 L376L355-L359 PolarHBondContact O-N 3Å; I356-L359 PolarHBondContact O-N 3.1Å; M357-L359 VanDerWaalsContact C-N 3.26Å; M357-L359 PolarHBondContact O-N 3.35Å; L359-W361 PolarHBondContact O-N 3.28Å; L359-S362 PolarHBondContact O-N 3.28Å; L359-L363 HydrophobicContact CD1-CD1 4.45Å; L359-L363 HydrophobicContact CD1-CD2 4.25Å; L359-L363 HydrophobicContact CD1-CG 4.14Å; L359-L363 HydrophobicContact CG-CD1 4.12Å; L359-L363 HydrophobicContact CG-CG 4.29Å; L359-L363 WeakPolarHBondContact O-CG 3.39Å; L359-L363 PolarHBondContact O-N 2.89Å; L359-Y373 HydrophobicContact CD1-CE1 4.21Å; L359-L376 HydrophobicContact CB-CD1 4.37Å; L359-L376 HydrophobicContact CB-CD2 4.16Å; L359-L376 HydrophobicContact CD1-CD2 3.85Å
360A98.3Very high96.8Very high0 Ų029.1 Ų29.10%017%0.166CC..Hα-helixtrans-60.5-29.4-179.700000113.7I293 I296 N297 I356 M357 S362 P364I293-A360 HydrophobicContact CG2-CB 4.43Å; I293-A360 WeakPolarHBondContact CG2-O 3.33Å; I296-A360 HydrophobicContact CB-CB 4.33Å; I296-A360 HydrophobicContact CG2-CB 3.97Å; N297-A360 HydrophobicContact CB-CB 3.68Å; I356-A360 PolarHBondContact O-N 3.39Å; M357-A360 CarbonylContact O-C 3.37Å; M357-A360 WeakPolarHBondContact O-CA 3.15Å; M357-A360 WeakPolarHBondContact O-CB 3.31Å; M357-A360 PolarHBondContact O-N 3.35Å; A360-S362 VanDerWaalsContact C-N 3.31Å; A360-P364 WeakPolarHBondContact O-CD 3.36Å
361W98.1Very high96.8Very high2 Ų228.5 Ų28.51%0.00816%0.163CC..Hα-helixtrans-73.1-26.6175.5-55.6-8.1000112.4W201 F229 Q230 Y233 N297 M357 L359 Y375W201-W361 HydrophobicContact CH2-CE3 4.5Å; W201-W361 AromaticContact CH2-CH2 3.97Å; W201-W361 HydrophobicContact CH2-CH2 3.97Å; W201-W361 AromaticContact CH2-CZ3 3.7Å; W201-W361 HydrophobicContact CH2-CZ3 3.7Å; W201-W361 HydrophobicContact CZ2-CZ3 4.12Å; F229-W361 VanDerWaalsContact CB-CD1 3.5Å; F229-W361 HydrophobicContact CB-CG 4.46Å; F229-W361 AromaticContact CD2-CD1 3.91Å; Q230-W361 HydrophobicContact CG-CD2 3.98Å; Q230-W361 HydrophobicContact CG-CE3 4.03Å; Q230-W361 HydrophobicContact CG-CG 4.28Å; Y233-W361 AromaticContact CD1-CH2 3.91Å; Y233-W361 HydrophobicContact CD1-CH2 3.91Å; Y233-W361 HydrophobicContact CD1-CZ2 4.46Å; Y233-W361 AromaticContact CD2-CH2 3.72Å; Y233-W361 HydrophobicContact CD2-CH2 3.72Å; Y233-W361 AromaticContact CD2-CZ2 3.68Å; Y233-W361 HydrophobicContact CD2-CZ2 3.68Å; Y233-W361 HydrophobicContact CE1-CH2 4.33Å; Y233-W361 HydrophobicContact CE2-CH2 4.15Å; Y233-W361 HydrophobicContact CE2-CZ2 4.44Å; Y233-W361 AromaticContact CG-CH2 3.58Å; Y233-W361 HydrophobicContact CG-CH2 3.58Å; Y233-W361 AromaticContact CG-CZ2 3.7Å; Y233-W361 HydrophobicContact CG-CZ2 3.7Å; N297-W361 PolarHBondContact OD1-NE1 3.03Å; M357-W361 HydrophobicContact CB-CZ2 3.97Å; M357-W361 PolarHBondContact O-N 2.79Å; M357-W361 PolarHBondContact O-NE1 3.49Å; L359-W361 PolarHBondContact O-N 3.28Å; W361-Y375 HydrophobicContact CE3-CD1 4.14Å; W361-Y375 AromaticContact CE3-CE1 3.49Å; W361-Y375 HydrophobicContact CE3-CE1 3.49Å; W361-Y375 VanDerWaalsContact CE3-CE1 3.49Å; W361-Y375 AromaticContact CE3-CZ 3.98Å; W361-Y375 AromaticContact CZ3-CE1 3.51Å; W361-Y375 HydrophobicContact CZ3-CE1 3.51Å; W361-Y375 AromaticContact CZ3-CZ 3.53Å; W361-Y375 VanDerWaalsContact CZ3-OH 3.26Å; W361-Y375 WeakPolarHBondContact CZ3-OH 3.42Å
362S98.1Very high96.7Very high0 Ų027.5 Ų27.50%016%0.159CC..Hα-helixtrans-89.4-31-176.9-52.10000112.6A358 L359 A360 P364 C365 P372A358-S362 PolarHBondContact O-N 3.31Å; A358-S362 PolarHBondContact O-OG 2.95Å; L359-S362 PolarHBondContact O-N 3.28Å; A360-S362 VanDerWaalsContact C-N 3.31Å; S362-P364 VanDerWaalsContact C-CD 3.45Å; S362-C365 VanDerWaalsContact O-CB 3.27Å; S362-C365 WeakPolarHBondContact O-CB 3.29Å; S362-C365 PolarHBondContact O-N 3.34Å; S362-P372 PolarHBondContact OG-O 3.49Å
363L98.1Very high96.7Very high42 Ų4227.7 Ų27.722%0.2216%0.158CC..G310 helixtrans-57.4-35.7-179-72.1171.9000115.4I293 I296 L359 C365 G366I293-L363 HydrophobicContact CD1-CB 3.77Å; I293-L363 HydrophobicContact CG1-CB 3.79Å; I293-L363 HydrophobicContact CG1-CD1 4.13Å; I293-L363 HydrophobicContact CG2-CB 4.36Å; I296-L363 HydrophobicContact CD1-CD1 3.74Å; L359-L363 HydrophobicContact CD1-CD1 4.45Å; L359-L363 HydrophobicContact CD1-CD2 4.25Å; L359-L363 HydrophobicContact CD1-CG 4.14Å; L359-L363 HydrophobicContact CG-CD1 4.12Å; L359-L363 HydrophobicContact CG-CG 4.29Å; L359-L363 WeakPolarHBondContact O-CG 3.39Å; L359-L363 PolarHBondContact O-N 2.89Å; L363-C365 PolarHBondContact O-N 3.05Å; L363-C365 VanDerWaalsContact O-N 3.12Å; L363-G366 PolarHBondContact O-N 3.46Å
364P98.1Very high96.7Very high1 Ų129.2 Ų29.21%0.00617%0.165CC..G310 helixtrans-58.4-22.6173.7-27.335.3000113.8A222 L225 V226 I293 A360 S362 G366A222-P364 HydrophobicContact CB-CB 3.9Å; A222-P364 WeakPolarHBondContact CB-O 3.26Å; L225-P364 HydrophobicContact CB-CG 4.2Å; V226-P364 HydrophobicContact CG2-CB 3.83Å; V226-P364 HydrophobicContact CG2-CG 3.95Å; I293-P364 HydrophobicContact CD1-CG 4.34Å; I293-P364 HydrophobicContact CG2-CG 4.16Å; A360-P364 WeakPolarHBondContact O-CD 3.36Å; S362-P364 VanDerWaalsContact C-CD 3.45Å; P364-G366 PolarHBondContact O-N 3.25Å
365C97.1Very high96.6Very high0 Ų028.8 Ų28.80%016%0.162CC..G310 helixtrans-81.36.4176.8-54.90000113.7F277 Q283 S362 L363 P372F277-C365 HydrophobicContact CD1-CB 3.69Å; F277-C365 HydrophobicContact CE1-CB 3.81Å; F277-C365 WeakPolarHBondContact CE1-O 3.44Å; Q283-C365 WeakPolarHBondContact CG-O 3.28Å; S362-C365 VanDerWaalsContact O-CB 3.27Å; S362-C365 WeakPolarHBondContact O-CB 3.29Å; S362-C365 PolarHBondContact O-N 3.34Å; L363-C365 PolarHBondContact O-N 3.05Å; L363-C365 VanDerWaalsContact O-N 3.12Å; C365-P372 HydrophobicContact CB-CB 3.54Å; C365-P372 HydrophobicContact CB-CG 3.49Å; C365-P372 VanDerWaalsContact CB-CG 3.49Å
366G95.3Very high96.6Very high20 Ų2029.2 Ų29.221%0.20617%0.165CC..  trans73.2-171.1-177.500000112.3L363 P364 Y373L363-G366 PolarHBondContact O-N 3.46Å; P364-G366 PolarHBondContact O-N 3.25Å; G366-Y373 WeakPolarHBondContact O-CE2 3.45Å; G366-Y373 PolarHBondContact O-OH 2.94Å
367V94.3Very high96.5Very high126 Ų12631.9 Ų31.976%0.76418%0.179SC*.SBendtrans-119.74.6-176.3-630000113.1
368S91.1Very high96.4Very high82 Ų8234.3 Ų34.357%0.57319%0.188SC*.SBendtrans-76.8-25.3-177.846.80000113.4
369H93.3Very high96.2Very high52 Ų5235 Ų3524%0.24119%0.191CC..  trans-122.3137.1-179-63.6-91.6000111.2F277 P372 Y373F277-H369 HydrophobicContact CE2-CB 3.79Å; F277-H369 AromaticContact CE2-CD2 3.88Å; F277-H369 AromaticContact CE2-CG 3.73Å; F277-H369 HydrophobicContact CZ-CB 3.86Å; F277-H369 AromaticContact CZ-CD2 3.51Å; F277-H369 AromaticContact CZ-CG 3.77Å; H369-P372 WeakPolarHBondContact O-CD 3.33Å; H369-Y373 WeakPolarHBondContact O-CD2 3.29Å
370L95.1Very high96.1Very high90 Ų9034.5 Ų34.547%0.47119%0.191SC..SBendtrans-79-20.5175.8-17062.3000112.7L44 Y373 F374 L377L44-L370 HydrophobicContact CB-CB 4.45Å; L44-L370 HydrophobicContact CD2-CB 4.44Å; L44-L370 HydrophobicContact CD2-CD2 3.85Å; L44-L370 HydrophobicContact CD2-CG 3.77Å; L370-Y373 WeakPolarHBondContact O-CB 3.34Å; L370-Y373 PolarHBondContact O-N 3.26Å; L370-F374 PolarHBondContact O-N 3.19Å; L370-L377 HydrophobicContact CD1-CD1 4.28Å
371L95.6Very high96Very high0 Ų037.6 Ų37.60%022%0.216CC..G310 helixtrans-55-48.2-174.2178.768.2000113.6L33 A36 A37 A42 L44 L273 F277 Y373 F374L33-L371 HydrophobicContact CD2-CD1 3.63Å; A36-L371 HydrophobicContact CB-CD1 4Å; A36-L371 HydrophobicContact CB-CD2 3.96Å; A37-L371 HydrophobicContact CB-CD2 4.17Å; A42-L371 HydrophobicContact CB-CD2 3.97Å; A42-L371 WeakPolarHBondContact O-CB 3.21Å; L44-L371 HydrophobicContact CB-CB 4.48Å; L44-L371 HydrophobicContact CD1-CD1 3.97Å; L273-L371 HydrophobicContact CD1-CD1 4.31Å; L273-L371 HydrophobicContact CD1-CD2 4.42Å; L273-L371 HydrophobicContact CD1-CG 4.23Å; L273-L371 HydrophobicContact CD2-CD1 4.11Å; L273-L371 HydrophobicContact CD2-CG 4.25Å; L273-L371 VanDerWaalsContact CD2-O 3.29Å; L273-L371 WeakPolarHBondContact CD2-O 3.49Å; L273-L371 HydrophobicContact CG-CG 4.47Å; F277-L371 HydrophobicContact CD2-CD2 4.37Å; L371-Y373 PolarHBondContact O-N 2.89Å; L371-F374 WeakPolarHBondContact O-CB 3.18Å; L371-F374 PolarHBondContact O-N 3.06Å
372P96.4Very high95.8Very high0 Ų040.3 Ų40.30%023%0.23CC..G310 helixtrans-62.7-26.2177.8-22.435.3000113.9Q274 F277 S362 C365 H369 F374Q274-P372 HydrophobicContact CG-CB 4.3Å; Q274-P372 PolarHBondContact NE2-O 3.46Å; F277-P372 HydrophobicContact CB-CG 4.21Å; F277-P372 HydrophobicContact CD1-CG 3.64Å; F277-P372 HydrophobicContact CD2-CG 3.92Å; F277-P372 HydrophobicContact CE1-CG 3.93Å; F277-P372 HydrophobicContact CE2-CG 4.19Å; F277-P372 HydrophobicContact CG-CG 3.64Å; F277-P372 HydrophobicContact CZ-CG 4.19Å; S362-P372 PolarHBondContact OG-O 3.49Å; C365-P372 HydrophobicContact CB-CB 3.54Å; C365-P372 HydrophobicContact CB-CG 3.49Å; C365-P372 VanDerWaalsContact CB-CG 3.49Å; H369-P372 WeakPolarHBondContact O-CD 3.33Å; P372-F374 VanDerWaalsContact C-N 3.3Å
373Y97.3Very high95.6Very high28 Ų2840.6 Ų40.611%0.1123%0.232CC..G310 helixtrans-83.1-4.7178.6-63.3-93.8000113L359 G366 H369 L370 L371 Y375 L376 L377L359-Y373 HydrophobicContact CD1-CE1 4.21Å; G366-Y373 WeakPolarHBondContact O-CE2 3.45Å; G366-Y373 PolarHBondContact O-OH 2.94Å; H369-Y373 WeakPolarHBondContact O-CD2 3.29Å; L370-Y373 WeakPolarHBondContact O-CB 3.34Å; L370-Y373 PolarHBondContact O-N 3.26Å; L371-Y373 PolarHBondContact O-N 2.89Å; Y373-Y375 PolarHBondContact O-N 3.46Å; Y373-L376 HydrophobicContact CD1-CD2 4.43Å; Y373-L376 PolarHBondContact O-N 3.47Å; Y373-L376 VanDerWaalsContact O-N 3.1Å; Y373-L377 WeakPolarHBondContact O-CG 3.34Å; Y373-L377 PolarHBondContact O-N 2.97Å
374F97.1Very high95.5Very high31 Ų3141.1 Ų41.114%0.13624%0.237CC..Hα-helixtrans-51.7-42.3171.7172.6-95.7000111.1T29 L33 L44 W266 L273 L370 L371 P372 L376 L377 Y378T29-F374 HydrophobicContact CG2-CE2 4.21Å; T29-F374 HydrophobicContact CG2-CZ 3.88Å; L33-F374 HydrophobicContact CD1-CD1 3.51Å; L33-F374 HydrophobicContact CD1-CE1 3.31Å; L33-F374 HydrophobicContact CD1-CE2 4.41Å; L33-F374 HydrophobicContact CD1-CG 4.18Å; L33-F374 HydrophobicContact CD1-CZ 3.8Å; L33-F374 HydrophobicContact CD2-CB 4.22Å; L33-F374 HydrophobicContact CD2-CD1 3.97Å; L33-F374 HydrophobicContact CD2-CD2 4.13Å; L33-F374 HydrophobicContact CD2-CE1 4.43Å; L33-F374 HydrophobicContact CD2-CG 3.81Å; L33-F374 HydrophobicContact CG-CD1 4.4Å; L33-F374 HydrophobicContact CG-CE1 4.47Å; L44-F374 HydrophobicContact CD1-CB 3.98Å; L44-F374 HydrophobicContact CD1-CD2 3.78Å; L44-F374 HydrophobicContact CD1-CG 4.15Å; L44-F374 HydrophobicContact CD2-CB 4.3Å; L44-F374 HydrophobicContact CD2-CD2 4.39Å; W266-F374 HydrophobicContact CH2-CE1 4.13Å; W266-F374 AromaticContact CH2-CZ 3.92Å; W266-F374 HydrophobicContact CH2-CZ 3.92Å; W266-F374 AromaticContact CZ2-CE1 3.91Å; W266-F374 HydrophobicContact CZ2-CE1 3.91Å; W266-F374 HydrophobicContact CZ2-CZ 4Å; L273-F374 HydrophobicContact CD2-CB 4.16Å; L273-F374 HydrophobicContact CD2-CD1 4.44Å; L370-F374 PolarHBondContact O-N 3.19Å; L371-F374 WeakPolarHBondContact O-CB 3.18Å; L371-F374 PolarHBondContact O-N 3.06Å; P372-F374 VanDerWaalsContact C-N 3.3Å; F374-L376 PolarHBondContact O-N 3.34Å; F374-L377 PolarHBondContact O-N 3.34Å; F374-Y378 HydrophobicContact CE1-CG 4.3Å; F374-Y378 HydrophobicContact CZ-CG 4.38Å; F374-Y378 VanDerWaalsContact O-CB 3.25Å; F374-Y378 WeakPolarHBondContact O-CB 3.41Å; F374-Y378 PolarHBondContact O-N 3.06Å
375Y95.6Very high95.2Very high3 Ų344.3 Ų44.31%0.01225%0.251CS..Hα-helixtrans-56-50.1177.3177.3-103.8000111.8Y271 A358 W361 Y373 L377 Y378 F379Y271-Y375 AromaticContact CD1-CD2 3.82Å; Y271-Y375 HydrophobicContact CD1-CD2 3.82Å; Y271-Y375 AromaticContact CD1-CE2 3.68Å; Y271-Y375 HydrophobicContact CD1-CE2 3.68Å; Y271-Y375 AromaticContact CD2-CE2 3.77Å; Y271-Y375 HydrophobicContact CD2-CE2 3.77Å; Y271-Y375 AromaticContact CE1-CD2 3.98Å; Y271-Y375 HydrophobicContact CE1-CD2 3.98Å; Y271-Y375 AromaticContact CE1-CE2 3.61Å; Y271-Y375 HydrophobicContact CE1-CE2 3.61Å; Y271-Y375 AromaticContact CE2-CE2 3.69Å; Y271-Y375 HydrophobicContact CE2-CE2 3.69Å; Y271-Y375 HydrophobicContact CG-CD2 4.15Å; Y271-Y375 AromaticContact CG-CE2 3.77Å; Y271-Y375 HydrophobicContact CG-CE2 3.77Å; Y271-Y375 AromaticContact CZ-CE2 3.61Å; A358-Y375 HydrophobicContact CB-CD1 3.74Å; A358-Y375 HydrophobicContact CB-CE1 3.37Å; W361-Y375 HydrophobicContact CE3-CD1 4.14Å; W361-Y375 AromaticContact CE3-CE1 3.49Å; W361-Y375 HydrophobicContact CE3-CE1 3.49Å; W361-Y375 VanDerWaalsContact CE3-CE1 3.49Å; W361-Y375 AromaticContact CE3-CZ 3.98Å; W361-Y375 AromaticContact CZ3-CE1 3.51Å; W361-Y375 HydrophobicContact CZ3-CE1 3.51Å; W361-Y375 AromaticContact CZ3-CZ 3.53Å; W361-Y375 VanDerWaalsContact CZ3-OH 3.26Å; W361-Y375 WeakPolarHBondContact CZ3-OH 3.42Å; Y373-Y375 PolarHBondContact O-N 3.46Å; Y375-L377 PolarHBondContact O-N 2.87Å; Y375-Y378 PolarHBondContact O-N 3.47Å; Y375-F379 HydrophobicContact CE1-CD1 4.4Å; Y375-F379 HydrophobicContact CE2-CB 4.49Å; Y375-F379 HydrophobicContact CE2-CG 4.47Å; Y375-F379 WeakPolarHBondContact O-CB 3.27Å; Y375-F379 PolarHBondContact O-N 2.72Å
376L96.8Very high95Very high33 Ų3346.6 Ų46.617%0.17326%0.26CS..Hα-helixtrans-59.7-45.3178.4176.263.6000111.8L355 A358 L359 Y373 F374 T380L355-L376 HydrophobicContact CD2-CD1 4.31Å; A358-L376 HydrophobicContact CB-CD1 3.87Å; L359-L376 HydrophobicContact CB-CD1 4.37Å; L359-L376 HydrophobicContact CB-CD2 4.16Å; L359-L376 HydrophobicContact CD1-CD2 3.85Å; Y373-L376 HydrophobicContact CD1-CD2 4.43Å; Y373-L376 PolarHBondContact O-N 3.47Å; Y373-L376 VanDerWaalsContact O-N 3.1Å; F374-L376 PolarHBondContact O-N 3.34Å; L376-T380 WeakPolarHBondContact O-CB 3.04Å; L376-T380 PolarHBondContact O-N 3.46Å; L376-T380 PolarHBondContact O-OG1 3.4Å
377L96.6Very high94.9Very high95 Ų9545.6 Ų45.650%0.49725%0.25SS..Hα-helixtrans-65.3-50-179.4-64175.2000111.7L370 Y373 F374 Y375 T380 A381L370-L377 HydrophobicContact CD1-CD1 4.28Å; Y373-L377 WeakPolarHBondContact O-CG 3.34Å; Y373-L377 PolarHBondContact O-N 2.97Å; F374-L377 PolarHBondContact O-N 3.34Å; Y375-L377 PolarHBondContact O-N 2.87Å; L377-T380 PolarHBondContact O-N 3.13Å; L377-A381 PolarHBondContact O-N 3.43Å; L377-A381 VanDerWaalsContact O-N 3.12Å
378Y95.3Very high94.9Very high55 Ų5541.1 Ų41.122%0.21623%0.226CC..Hα-helixtrans-58.8-48.7176.2158.4-102.8000111.2W266 Y271 F374 Y375 T380 A381 L382W266-Y378 AromaticContact CE2-CE2 3.98Å; W266-Y378 AromaticContact CE2-CZ 3.75Å; W266-Y378 HydrophobicContact CZ2-CD1 4.32Å; W266-Y378 AromaticContact CZ2-CD2 3.8Å; W266-Y378 HydrophobicContact CZ2-CD2 3.8Å; W266-Y378 HydrophobicContact CZ2-CE1 4.22Å; W266-Y378 AromaticContact CZ2-CE2 3.67Å; W266-Y378 HydrophobicContact CZ2-CE2 3.67Å; W266-Y378 HydrophobicContact CZ2-CG 4.12Å; W266-Y378 AromaticContact CZ2-CZ 3.89Å; W266-Y378 AromaticContact NE1-CE1 3.31Å; W266-Y378 VanDerWaalsContact NE1-CE1 3.31Å; W266-Y378 AromaticContact NE1-CE2 3.9Å; W266-Y378 AromaticContact NE1-CZ 3.18Å; W266-Y378 PolarHBondContact NE1-OH 2.75Å; W266-Y378 VanDerWaalsContact NE1-OH 3.16Å; Y271-Y378 HydrophobicContact CE1-CE1 4.09Å; F374-Y378 HydrophobicContact CE1-CG 4.3Å; F374-Y378 HydrophobicContact CZ-CG 4.38Å; F374-Y378 VanDerWaalsContact O-CB 3.25Å; F374-Y378 WeakPolarHBondContact O-CB 3.41Å; F374-Y378 PolarHBondContact O-N 3.06Å; Y375-Y378 PolarHBondContact O-N 3.47Å; Y378-T380 VanDerWaalsContact C-N 3.32Å; Y378-T380 PolarHBondContact O-N 3.45Å; Y378-A381 PolarHBondContact O-N 3.47Å; Y378-L382 HydrophobicContact CE1-CD2 4.34Å; Y378-L382 WeakPolarHBondContact O-CB 3.29Å; Y378-L382 PolarHBondContact O-N 2.86Å
379F94.4Very high94.8Very high14 Ų1437.8 Ų37.86%0.06120%0.201CC..Hα-helixtrans-68.4-34-175.6-160.9-128.6000111.5D354 L355 A358 Y375 L382 L383D354-F379 HydrophobicContact CB-CE1 3.8Å; D354-F379 HydrophobicContact CB-CZ 4.46Å; L355-F379 HydrophobicContact CD2-CD1 4.37Å; A358-F379 HydrophobicContact CB-CD1 4.28Å; Y375-F379 HydrophobicContact CE1-CD1 4.4Å; Y375-F379 HydrophobicContact CE2-CB 4.49Å; Y375-F379 HydrophobicContact CE2-CG 4.47Å; Y375-F379 WeakPolarHBondContact O-CB 3.27Å; Y375-F379 PolarHBondContact O-N 2.72Å; F379-L382 HydrophobicContact CD2-CD2 3.9Å; F379-L382 HydrophobicContact CE2-CD2 4.07Å; F379-L382 PolarHBondContact O-N 3.33Å; F379-L383 HydrophobicContact CD1-CD1 3.89Å; F379-L383 HydrophobicContact CD1-CG 4.46Å; F379-L383 HydrophobicContact CE1-CD1 3.86Å; F379-L383 HydrophobicContact CE1-CG 4.45Å; F379-L383 HydrophobicContact CG-CD1 4.44Å; F379-L383 HydrophobicContact CZ-CD1 4.31Å; F379-L383 HydrophobicContact CZ-CD2 4.41Å; F379-L383 HydrophobicContact CZ-CG 4.48Å; F379-L383 WeakPolarHBondContact O-CB 3.35Å; F379-L383 VanDerWaalsContact O-CG 3.26Å; F379-L383 WeakPolarHBondContact O-CG 3.29Å; F379-L383 PolarHBondContact O-N 3.41Å
380T96.5Very high94.7Very high51 Ų5137.3 Ų37.331%0.31320%0.2SC..Hα-helixtrans-60.1-49.4169.8-55.70000111.6L355 L376 L377 Y378 L382 L383 V384L355-T380 VanDerWaalsContact CD2-OG1 3.27Å; L355-T380 WeakPolarHBondContact CD2-OG1 3.36Å; L376-T380 WeakPolarHBondContact O-CB 3.04Å; L376-T380 PolarHBondContact O-N 3.46Å; L376-T380 PolarHBondContact O-OG1 3.4Å; L377-T380 PolarHBondContact O-N 3.13Å; Y378-T380 VanDerWaalsContact C-N 3.32Å; Y378-T380 PolarHBondContact O-N 3.45Å; T380-L382 VanDerWaalsContact C-N 3.31Å; T380-L382 PolarHBondContact O-N 3.41Å; T380-L383 PolarHBondContact O-N 3.42Å; T380-V384 WeakPolarHBondContact O-CG2 3.47Å; T380-V384 PolarHBondContact O-N 3.28Å
381A95.8Very high94.6Very high64 Ų6434.3 Ų34.353%0.52918%0.184SC..Hα-helixtrans-61.3-41177.400000112L377 Y378 H385L377-A381 PolarHBondContact O-N 3.43Å; L377-A381 VanDerWaalsContact O-N 3.12Å; Y378-A381 PolarHBondContact O-N 3.47Å; A381-H385 WeakPolarHBondContact O-CB 3.37Å; A381-H385 PolarHBondContact O-N 3.28Å
382L93.4Very high94.4Very high59 Ų5939.1 Ų39.131%0.30920%0.202SC..Hα-helixtrans-61.1-47.7175.9-177.171.4000111.6Y378 F379 T380 H385 R386Y378-L382 HydrophobicContact CE1-CD2 4.34Å; Y378-L382 WeakPolarHBondContact O-CB 3.29Å; Y378-L382 PolarHBondContact O-N 2.86Å; F379-L382 HydrophobicContact CD2-CD2 3.9Å; F379-L382 HydrophobicContact CE2-CD2 4.07Å; F379-L382 PolarHBondContact O-N 3.33Å; T380-L382 VanDerWaalsContact C-N 3.31Å; T380-L382 PolarHBondContact O-N 3.41Å; L382-H385 PolarHBondContact O-N 3.33Å; L382-R386 VanDerWaalsContact O-CB 3.26Å; L382-R386 WeakPolarHBondContact O-CB 3.1Å; L382-R386 PolarHBondContact O-N 3.44Å
383L94.7Very high93.9Very high6 Ų641.2 Ų41.23%0.03121%0.212CC..Hα-helixtrans-68.8-37.9-177.9-70.5177.3000112.4Y351 D354 L355 F379 T380 R386 E387Y351-L383 HydrophobicContact CD1-CD2 3.68Å; Y351-L383 HydrophobicContact CD2-CB 4.46Å; Y351-L383 HydrophobicContact CD2-CD2 4.24Å; Y351-L383 HydrophobicContact CE1-CD2 4Å; Y351-L383 HydrophobicContact CG-CD1 4.46Å; Y351-L383 HydrophobicContact CG-CD2 3.84Å; Y351-L383 HydrophobicContact CG-CG 4.5Å; D354-L383 HydrophobicContact CB-CD1 4.25Å; L355-L383 HydrophobicContact CD2-CD1 3.79Å; L355-L383 HydrophobicContact CG-CD1 3.84Å; F379-L383 HydrophobicContact CD1-CD1 3.89Å; F379-L383 HydrophobicContact CD1-CG 4.46Å; F379-L383 HydrophobicContact CE1-CD1 3.86Å; F379-L383 HydrophobicContact CE1-CG 4.45Å; F379-L383 HydrophobicContact CG-CD1 4.44Å; F379-L383 HydrophobicContact CZ-CD1 4.31Å; F379-L383 HydrophobicContact CZ-CD2 4.41Å; F379-L383 HydrophobicContact CZ-CG 4.48Å; F379-L383 WeakPolarHBondContact O-CB 3.35Å; F379-L383 VanDerWaalsContact O-CG 3.26Å; F379-L383 WeakPolarHBondContact O-CG 3.29Å; F379-L383 PolarHBondContact O-N 3.41Å; T380-L383 PolarHBondContact O-N 3.42Å; L383-R386 PolarHBondContact O-N 3.05Å; L383-E387 VanDerWaalsContact O-CB 3.27Å; L383-E387 WeakPolarHBondContact O-CB 3.49Å; L383-E387 PolarHBondContact O-N 3.46Å
384V95.2Very high93.7Very high54 Ų5440.6 Ų40.633%0.32721%0.212SC..Hα-helixtrans-63.6-45173.1170.70000110.8T380 R386 E387 A388 I413 Y418T380-V384 WeakPolarHBondContact O-CG2 3.47Å; T380-V384 PolarHBondContact O-N 3.28Å; V384-R386 PolarHBondContact O-N 2.85Å; V384-E387 PolarHBondContact O-N 2.91Å; V384-A388 WeakPolarHBondContact O-CB 3.42Å; V384-A388 PolarHBondContact O-N 3.37Å; V384-I413 HydrophobicContact CG2-CD1 4.27Å; V384-Y418 HydrophobicContact CG2-CE1 4.46Å
385H92.5Very high93.4Very high67 Ų6742.7 Ų42.731%0.3122%0.224SC..Hα-helixtrans-62.7-43.1175.5-178.9-105.3000111.7F13 A381 L382 A388 R389F13-H385 AromaticContact CE1-CE1 3.59Å; F13-H385 AromaticContact CZ-CE1 3.78Å; A381-H385 WeakPolarHBondContact O-CB 3.37Å; A381-H385 PolarHBondContact O-N 3.28Å; L382-H385 PolarHBondContact O-N 3.33Å; H385-A388 PolarHBondContact O-N 2.9Å; H385-R389 WeakPolarHBondContact O-CG 3.45Å; H385-R389 PolarHBondContact O-N 2.87Å; H385-R389 VanDerWaalsContact O-N 3.11Å
386R92.6Very high93.2Very high48 Ų4849.7 Ų49.718%0.18126%0.256CS..Hα-helixtrans-65.2-42.2179.2-169.5176.1-177.4113-5.9111.9D249 L382 L383 V384 R389 D390D249-R386 IonicContact OD1-CZ 3.42Å; D249-R386 IonicContact OD1-NH1 3.51Å; D249-R386 PolarHBondContact OD1-NH1 3.29Å; D249-R386 IonicContact OD1-NH2 2.63Å; D249-R386 IonicContact OD2-CZ 3.28Å; D249-R386 VanDerWaalsContact OD2-CZ 3.28Å; D249-R386 IonicContact OD2-NH1 3.47Å; D249-R386 PolarHBondContact OD2-NH1 3.45Å; D249-R386 IonicContact OD2-NH2 3.12Å; D249-R386 PolarHBondContact OD2-NH2 3.14Å; L382-R386 VanDerWaalsContact O-CB 3.26Å; L382-R386 WeakPolarHBondContact O-CB 3.1Å; L382-R386 PolarHBondContact O-N 3.44Å; L383-R386 PolarHBondContact O-N 3.05Å; V384-R386 PolarHBondContact O-N 2.85Å; R386-R389 PolarHBondContact O-N 3.42Å; R386-D390 PolarHBondContact O-N 3.09Å
387E94.3Very high92.8Very high0 Ų052.6 Ų52.60%027%0.268CS..Hα-helixtrans-59.9-48.1173.5179-85.8151.800111.1H348 Y351 L383 V384 R389 D390 E391 R412 I413 Y418H348-E387 WeakPolarHBondContact CD2-CG 3.47Å; Y351-E387 HydrophobicContact CD2-CB 4.39Å; Y351-E387 HydrophobicContact CE2-CB 4.14Å; L383-E387 VanDerWaalsContact O-CB 3.27Å; L383-E387 WeakPolarHBondContact O-CB 3.49Å; L383-E387 PolarHBondContact O-N 3.46Å; V384-E387 PolarHBondContact O-N 2.91Å; E387-R389 PolarHBondContact O-N 3.42Å; E387-D390 PolarHBondContact O-N 2.89Å; E387-D390 VanDerWaalsContact O-N 3.1Å; E387-E391 VanDerWaalsContact O-CB 3.31Å; E387-E391 WeakPolarHBondContact O-CB 3.27Å; E387-E391 PolarHBondContact O-N 2.89Å; E387-R412 HydrophobicContact CG-CB 4.22Å; E387-R412 WeakPolarHBondContact OE1-CD 3.27Å; E387-R412 VanDerWaalsContact OE1-CG 3.25Å; E387-R412 WeakPolarHBondContact OE1-CG 3.44Å; E387-R412 IonicContact OE1-CZ 2.86Å; E387-R412 IonicContact OE1-NE 3.4Å; E387-R412 IonicContact OE1-NH1 2.71Å; E387-R412 PolarHBondContact OE1-NH1 2.87Å; E387-R412 IonicContact OE2-CZ 3.44Å; E387-R412 IonicContact OE2-NH1 2.77Å; E387-R412 PolarHBondContact OE2-NH1 3.37Å; E387-I413 HydrophobicContact CB-CD1 4.27Å; E387-I413 HydrophobicContact CG-CG1 4.43Å; E387-Y418 PolarHBondContact OE2-OH 2.99Å
388A92.4Very high92.7Very high32 Ų3249.5 Ų49.526%0.26425%0.25SC..Hα-helixtrans-62.5-27.8178.700000113.5V384 H385 R392V384-A388 WeakPolarHBondContact O-CB 3.42Å; V384-A388 PolarHBondContact O-N 3.37Å; H385-A388 PolarHBondContact O-N 2.9Å; A388-R392 WeakPolarHBondContact O-CG 3.33Å; A388-R392 PolarHBondContact O-N 3.43Å; A388-R392 PolarHBondContact O-NE 2.96Å; A388-R392 VanDerWaalsContact O-NE 3.1Å
389R90.9Very high92.6Very high11 Ų1148.2 Ų48.24%0.04225%0.253CS..Hα-helixtrans-72.7-48.7171.1-68.2174.173.3-149.51.6111.3E12 M248 D253 H385 R386 E387 E391 R392 Q393E12-R389 IonicContact OE1-CZ 3.87Å; E12-R389 IonicContact OE1-NE 3.85Å; E12-R389 PolarHBondContact OE1-NE 3.37Å; E12-R389 IonicContact OE1-NH2 3.75Å; E12-R389 PolarHBondContact OE1-NH2 2.96Å; E12-R389 IonicContact OE2-CZ 3.79Å; E12-R389 IonicContact OE2-NE 3.28Å; E12-R389 PolarHBondContact OE2-NE 3.09Å; E12-R389 IonicContact OE2-NH2 2.85Å; E12-R389 PolarHBondContact OE2-NH2 3.36Å; M248-R389 HydrophobicContact CE-CB 4.12Å; M248-R389 HydrophobicContact SD-CB 4.22Å; M248-R389 VanDerWaalsContact SD-CZ 3.56Å; M248-R389 PolarHBondContact SD-NH1 3.36Å; D253-R389 IonicContact OD1-CZ 3.94Å; D253-R389 IonicContact OD1-NH1 3.74Å; D253-R389 IonicContact OD1-NH2 3.06Å; D253-R389 PolarHBondContact OD1-NH2 2.96Å; D253-R389 IonicContact OD2-CZ 2.72Å; D253-R389 IonicContact OD2-NH1 2.81Å; D253-R389 PolarHBondContact OD2-NH1 3.09Å; D253-R389 IonicContact OD2-NH2 2.77Å; D253-R389 PolarHBondContact OD2-NH2 3.11Å; H385-R389 WeakPolarHBondContact O-CG 3.45Å; H385-R389 PolarHBondContact O-N 2.87Å; H385-R389 VanDerWaalsContact O-N 3.11Å; R386-R389 PolarHBondContact O-N 3.42Å; E387-R389 PolarHBondContact O-N 3.42Å; R389-E391 VanDerWaalsContact C-N 3.3Å; R389-E391 PolarHBondContact O-N 3.18Å; R389-R392 PolarHBondContact O-N 2.97Å; R389-Q393 WeakPolarHBondContact O-CG 3.18Å; R389-Q393 PolarHBondContact O-N 3.33Å
390D90.8Very high92.6Very high42 Ų4254.2 Ų54.223%0.22529%0.285CS..Hα-helixtrans-61.8-39.6179.9-16656.2000111.6M248 H348 R386 E387 R392 Q393 C394M248-D390 HydrophobicContact CE-CB 3.86Å; H348-D390 IonicContact CE1-OD2 3.21Å; H348-D390 PolarHBondContact CE1-OD2 3.45Å; H348-D390 VanDerWaalsContact CE1-OD2 3.23Å; H348-D390 IonicContact NE2-OD2 3.66Å; R386-D390 PolarHBondContact O-N 3.09Å; E387-D390 PolarHBondContact O-N 2.89Å; E387-D390 VanDerWaalsContact O-N 3.1Å; D390-R392 PolarHBondContact O-N 3.45Å; D390-Q393 PolarHBondContact O-N 2.75Å; D390-C394 VanDerWaalsContact O-CB 3.28Å; D390-C394 WeakPolarHBondContact O-CB 3.29Å; D390-C394 PolarHBondContact O-N 2.8Å; D390-C394 PolarHBondContact O-SG 3.23Å; D390-C394 VanDerWaalsContact O-SG 3.33Å
391E92.3Very high92.6Very high28 Ų2852.5 Ų52.513%0.13128%0.276CS..Hα-helixtrans-58.6-46.3175.2-177.471.1-142.900111.5R347 E387 R389 C394 L395 W402 C406R347-E391 IonicContact CZ-OE2 3.78Å; R347-E391 IonicContact NE-OE2 2.72Å; R347-E391 PolarHBondContact NE-OE2 3.48Å; R347-E391 IonicContact NH2-OE1 3.48Å; R347-E391 IonicContact NH2-OE2 3.76Å; R347-E391 PolarHBondContact NH2-OE2 2.87Å; E387-E391 VanDerWaalsContact O-CB 3.31Å; E387-E391 WeakPolarHBondContact O-CB 3.27Å; E387-E391 PolarHBondContact O-N 2.89Å; R389-E391 VanDerWaalsContact C-N 3.3Å; R389-E391 PolarHBondContact O-N 3.18Å; E391-C394 PolarHBondContact O-N 2.84Å; E391-L395 VanDerWaalsContact O-CB 3.3Å; E391-L395 WeakPolarHBondContact O-CB 3.26Å; E391-L395 PolarHBondContact O-N 2.86Å; E391-W402 VanDerWaalsContact CD-NE1 3.31Å; E391-W402 PolarHBondContact OE1-NE1 3.07Å; E391-C406 PolarHBondContact OE1-SG 2.91Å
392R91Very high92.6Very high101 Ų10150 Ų5038%0.38125%0.253SS..Hα-helixtrans-64.3-43.3176.5-74.7-179.1-71.3165.22111.8A388 R389 D390 L395 Q396A388-R392 WeakPolarHBondContact O-CG 3.33Å; A388-R392 PolarHBondContact O-N 3.43Å; A388-R392 PolarHBondContact O-NE 2.96Å; A388-R392 VanDerWaalsContact O-NE 3.1Å; R389-R392 PolarHBondContact O-N 2.97Å; D390-R392 PolarHBondContact O-N 3.45Å; R392-L395 PolarHBondContact O-N 2.85Å; R392-Q396 VanDerWaalsContact O-CG 3.3Å; R392-Q396 WeakPolarHBondContact O-CG 3.48Å; R392-Q396 PolarHBondContact O-N 3.49Å
393Q87.6Confident92.7Very high44 Ų4452.5 Ų52.521%0.20626%0.263CS..Hα-helixtrans-66.2-43.7178.7-69.8178.58.900111.6R389 D390 Q396 K397R389-Q393 WeakPolarHBondContact O-CG 3.18Å; R389-Q393 PolarHBondContact O-N 3.33Å; D390-Q393 PolarHBondContact O-N 2.75Å; Q393-Q396 PolarHBondContact O-N 3.26Å; Q393-K397 VanDerWaalsContact O-CB 3.22Å; Q393-K397 WeakPolarHBondContact O-CB 3.21Å; Q393-K397 PolarHBondContact O-N 3.43Å
394C91.3Very high92.8Very high15 Ų1554.7 Ų54.710%0.10127%0.273CS..Hα-helixtrans-66.2-38.1177.8-74.30000111.9D390 E391 K397 Y398 W402D390-C394 VanDerWaalsContact O-CB 3.28Å; D390-C394 WeakPolarHBondContact O-CB 3.29Å; D390-C394 PolarHBondContact O-N 2.8Å; D390-C394 PolarHBondContact O-SG 3.23Å; D390-C394 VanDerWaalsContact O-SG 3.33Å; E391-C394 PolarHBondContact O-N 2.84Å; C394-K397 PolarHBondContact O-N 3.32Å; C394-Y398 HydrophobicContact CB-CD2 4.12Å; C394-Y398 HydrophobicContact CB-CE2 4.39Å; C394-Y398 WeakPolarHBondContact O-CB 3.36Å; C394-Y398 WeakPolarHBondContact O-CD2 3.47Å; C394-Y398 PolarHBondContact O-N 2.94Å; C394-W402 HydrophobicContact CB-CD2 3.47Å; C394-W402 VanDerWaalsContact CB-CD2 3.47Å; C394-W402 VanDerWaalsContact CB-CE2 3.47Å; C394-W402 HydrophobicContact CB-CE3 3.6Å; C394-W402 HydrophobicContact CB-CG 4.13Å; C394-W402 HydrophobicContact CB-CH2 3.72Å; C394-W402 HydrophobicContact CB-CZ2 3.62Å; C394-W402 HydrophobicContact CB-CZ3 3.71Å
395L92.6Very high92.9Very high75 Ų7552.6 Ų52.639%0.39326%0.259SS..Hα-helixtrans-63.4-46.1173.8-178.662.2000111.8E391 R392 K397 G399 Q403E391-L395 VanDerWaalsContact O-CB 3.3Å; E391-L395 WeakPolarHBondContact O-CB 3.26Å; E391-L395 PolarHBondContact O-N 2.86Å; R392-L395 PolarHBondContact O-N 2.85Å; L395-K397 VanDerWaalsContact C-N 3.29Å; L395-K397 PolarHBondContact O-N 2.93Å; L395-G399 VanDerWaalsContact O-CA 3.29Å; L395-G399 WeakPolarHBondContact O-CA 3.37Å; L395-G399 PolarHBondContact O-N 3.47Å; L395-Q403 HydrophobicContact CD1-CG 3.87Å
396Q89.9Confident93.1Very high149 Ų14950.6 Ų50.670%0.69625%0.253SS*.Hα-helixtrans-61.6-38.3176.1-73.6173.3-300112R392 Q393R392-Q396 VanDerWaalsContact O-CG 3.3Å; R392-Q396 WeakPolarHBondContact O-CG 3.48Å; R392-Q396 PolarHBondContact O-N 3.49Å; Q393-Q396 PolarHBondContact O-N 3.26Å
397K89.7Confident93.3Very high95 Ų9556.3 Ų56.341%0.41327%0.274SS..Hα-helixtrans-80.2-40.3-175.2-175.2173.2-178.8168.20114.1T333 Q393 C394 L395T333-K397 HydrophobicContact CG2-CG 4.45Å; Q393-K397 VanDerWaalsContact O-CB 3.22Å; Q393-K397 WeakPolarHBondContact O-CB 3.21Å; Q393-K397 PolarHBondContact O-N 3.43Å; C394-K397 PolarHBondContact O-N 3.32Å; L395-K397 VanDerWaalsContact C-N 3.29Å; L395-K397 PolarHBondContact O-N 2.93Å
398Y92.8Very high93.4Very high30 Ų3061.7 Ų61.712%0.11830%0.295CS..Hα-helixtrans-113.9-10.8-170.9-53.5-60.5000113.8T331 T333 L337 C394 L400 A401 W402T331-Y398 HydrophobicContact CG2-CD1 3.62Å; T331-Y398 HydrophobicContact CG2-CE1 4.17Å; T331-Y398 HydrophobicContact CG2-CG 4.08Å; T333-Y398 HydrophobicContact CG2-CD1 4.09Å; T333-Y398 HydrophobicContact CG2-CE1 4.26Å; L337-Y398 HydrophobicContact CD1-CD2 4.41Å; L337-Y398 HydrophobicContact CD2-CD2 4.08Å; L337-Y398 HydrophobicContact CD2-CE2 3.86Å; C394-Y398 HydrophobicContact CB-CD2 4.12Å; C394-Y398 HydrophobicContact CB-CE2 4.39Å; C394-Y398 WeakPolarHBondContact O-CB 3.36Å; C394-Y398 WeakPolarHBondContact O-CD2 3.47Å; C394-Y398 PolarHBondContact O-N 2.94Å; Y398-L400 PolarHBondContact O-N 2.83Å; Y398-A401 PolarHBondContact O-N 3.14Å; Y398-A401 VanDerWaalsContact O-N 3.16Å; Y398-W402 HydrophobicContact CD2-CE3 4.27Å
399G93.8Very high93.6Very high28 Ų2860.2 Ų60.229%0.28928%0.282SS..THydrogen-bonded Turntrans53.7-122.3172.700000113.3L395 A401 W402 Q403L395-G399 VanDerWaalsContact O-CA 3.29Å; L395-G399 WeakPolarHBondContact O-CA 3.37Å; L395-G399 PolarHBondContact O-N 3.47Å; G399-A401 PolarHBondContact O-N 2.92Å; G399-W402 WeakPolarHBondContact O-CB 3.21Å; G399-W402 PolarHBondContact O-N 3.4Å; G399-Q403 PolarHBondContact O-N 3.48Å; G399-Q403 VanDerWaalsContact O-N 3.13Å
400L95Very high93.8Very high140 Ų14063 Ų6373%0.73330%0.302SS*.Hα-helixtrans-56.5-35-178.6-64.8177000113.4Y398 W402 Q403 E404Y398-L400 PolarHBondContact O-N 2.83Å; L400-W402 VanDerWaalsContact C-N 3.28Å; L400-W402 PolarHBondContact O-N 3Å; L400-Q403 PolarHBondContact O-N 3.27Å; L400-E404 PolarHBondContact O-N 2.86Å
401A95.4Very high94.1Very high14 Ų1464.5 Ų64.512%0.11631%0.305CS..Hα-helixtrans-65.9-3417800000111.7I329 T331 Y398 G399 Y405I329-A401 HydrophobicContact CG2-CB 3.87Å; T331-A401 HydrophobicContact CG2-CB 3.96Å; Y398-A401 PolarHBondContact O-N 3.14Å; Y398-A401 VanDerWaalsContact O-N 3.16Å; G399-A401 PolarHBondContact O-N 2.92Å; A401-Y405 PolarHBondContact O-N 3.26Å
402W96.5Very high94.2Very high13 Ų1366.7 Ų66.75%0.04931%0.312CS..Hα-helixtrans-71.8-38.7174-170.8-108.3000112.3L337 E391 C394 Y398 G399 L400 E404 Y405 C406L337-W402 HydrophobicContact CD1-CE3 3.93Å; L337-W402 HydrophobicContact CD1-CZ3 4.47Å; E391-W402 VanDerWaalsContact CD-NE1 3.31Å; E391-W402 PolarHBondContact OE1-NE1 3.07Å; C394-W402 HydrophobicContact CB-CD2 3.47Å; C394-W402 VanDerWaalsContact CB-CD2 3.47Å; C394-W402 VanDerWaalsContact CB-CE2 3.47Å; C394-W402 HydrophobicContact CB-CE3 3.6Å; C394-W402 HydrophobicContact CB-CG 4.13Å; C394-W402 HydrophobicContact CB-CH2 3.72Å; C394-W402 HydrophobicContact CB-CZ2 3.62Å; C394-W402 HydrophobicContact CB-CZ3 3.71Å; Y398-W402 HydrophobicContact CD2-CE3 4.27Å; G399-W402 WeakPolarHBondContact O-CB 3.21Å; G399-W402 PolarHBondContact O-N 3.4Å; L400-W402 VanDerWaalsContact C-N 3.28Å; L400-W402 PolarHBondContact O-N 3Å; W402-E404 VanDerWaalsContact C-N 3.33Å; W402-E404 PolarHBondContact O-N 3.17Å; W402-Y405 HydrophobicContact CD2-CD1 4.19Å; W402-Y405 AromaticContact CE3-CD1 3.62Å; W402-Y405 HydrophobicContact CE3-CD1 3.62Å; W402-Y405 HydrophobicContact CE3-CE1 4.33Å; W402-Y405 HydrophobicContact CE3-CG 4.38Å; W402-Y405 AromaticContact CH2-CD1 3.61Å; W402-Y405 HydrophobicContact CH2-CD1 3.61Å; W402-Y405 AromaticContact CH2-CE1 3.56Å; W402-Y405 HydrophobicContact CH2-CE1 3.56Å; W402-Y405 HydrophobicContact CZ2-CD1 4.14Å; W402-Y405 HydrophobicContact CZ2-CE1 4.33Å; W402-Y405 AromaticContact CZ3-CD1 3.31Å; W402-Y405 HydrophobicContact CZ3-CD1 3.31Å; W402-Y405 AromaticContact CZ3-CE1 3.55Å; W402-Y405 HydrophobicContact CZ3-CE1 3.55Å; W402-Y405 HydrophobicContact CZ3-CG 4.35Å; W402-Y405 WeakPolarHBondContact O-CB 3.43Å; W402-Y405 PolarHBondContact O-N 2.92Å; W402-C406 PolarHBondContact NE1-SG 3.07Å; W402-C406 VanDerWaalsContact NE1-SG 3.4Å; W402-C406 PolarHBondContact O-N 3.3Å; W402-C406 PolarHBondContact O-SG 3.4Å
403Q96.3Very high94.5Very high110 Ų11062 Ų6251%0.51430%0.295SS..Hα-helixtrans-62-42.7175.5-67.1178.4-6.900111.5L395 G399 L400 Y405 C406 R407L395-Q403 HydrophobicContact CD1-CG 3.87Å; G399-Q403 PolarHBondContact O-N 3.48Å; G399-Q403 VanDerWaalsContact O-N 3.13Å; L400-Q403 PolarHBondContact O-N 3.27Å; Q403-Y405 VanDerWaalsContact C-N 3.33Å; Q403-Y405 PolarHBondContact O-N 3.22Å; Q403-C406 PolarHBondContact O-N 3.38Å; Q403-R407 PolarHBondContact O-N 3.46Å
404E96.5Very high94.8Very high53 Ų5362 Ų6225%0.24830%0.297CS..Hα-helixtrans-64.1-38.7173.7176.358.5-170.100111.8I329 L400 W402 R407 R408I329-E404 HydrophobicContact CD1-CB 4.17Å; I329-E404 HydrophobicContact CD1-CG 3.73Å; L400-E404 PolarHBondContact O-N 2.86Å; W402-E404 VanDerWaalsContact C-N 3.33Å; W402-E404 PolarHBondContact O-N 3.17Å; E404-R407 PolarHBondContact O-N 2.96Å; E404-R407 IonicContact OE1-CZ 3.7Å; E404-R407 IonicContact OE1-NE 3.38Å; E404-R407 IonicContact OE1-NH2 2.8Å; E404-R407 PolarHBondContact OE1-NH2 2.84Å; E404-R407 IonicContact OE2-CZ 3.48Å; E404-R407 IonicContact OE2-NE 3.07Å; E404-R407 PolarHBondContact OE2-NE 2.93Å; E404-R407 IonicContact OE2-NH2 3.3Å; E404-R407 PolarHBondContact OE2-NH2 2.93Å; E404-R408 PolarHBondContact O-N 3.38Å; E404-R408 VanDerWaalsContact O-N 3.1Å; E404-R408 IonicContact OE1-CZ 2.69Å; E404-R408 IonicContact OE1-NE 2.76Å; E404-R408 PolarHBondContact OE1-NE 3.08Å; E404-R408 IonicContact OE1-NH2 2.83Å; E404-R408 PolarHBondContact OE1-NH2 2.93Å
405Y96.8Very high94.8Very high9 Ų962.9 Ų62.94%0.03530%0.303CS..Hα-helixtrans-59-48172.9178.2-121.8000111.7L338 V339 W343 R347 A401 W402 Q403 R407 R408 V409L338-Y405 WeakPolarHBondContact O-CE2 3.33Å; V339-Y405 HydrophobicContact CB-CD2 4.15Å; V339-Y405 HydrophobicContact CB-CE2 4.28Å; V339-Y405 HydrophobicContact CG1-CD2 3.39Å; V339-Y405 HydrophobicContact CG1-CE2 3.83Å; V339-Y405 HydrophobicContact CG1-CG 4.49Å; W343-Y405 PolarHBondContact O-OH 3.15Å; W343-Y405 VanDerWaalsContact O-OH 3.1Å; R347-Y405 HydrophobicContact CB-CE1 4.12Å; R347-Y405 HydrophobicContact CG-CD1 4.37Å; R347-Y405 HydrophobicContact CG-CE1 3.65Å; A401-Y405 PolarHBondContact O-N 3.26Å; W402-Y405 HydrophobicContact CD2-CD1 4.19Å; W402-Y405 AromaticContact CE3-CD1 3.62Å; W402-Y405 HydrophobicContact CE3-CD1 3.62Å; W402-Y405 HydrophobicContact CE3-CE1 4.33Å; W402-Y405 HydrophobicContact CE3-CG 4.38Å; W402-Y405 AromaticContact CH2-CD1 3.61Å; W402-Y405 HydrophobicContact CH2-CD1 3.61Å; W402-Y405 AromaticContact CH2-CE1 3.56Å; W402-Y405 HydrophobicContact CH2-CE1 3.56Å; W402-Y405 HydrophobicContact CZ2-CD1 4.14Å; W402-Y405 HydrophobicContact CZ2-CE1 4.33Å; W402-Y405 AromaticContact CZ3-CD1 3.31Å; W402-Y405 HydrophobicContact CZ3-CD1 3.31Å; W402-Y405 AromaticContact CZ3-CE1 3.55Å; W402-Y405 HydrophobicContact CZ3-CE1 3.55Å; W402-Y405 HydrophobicContact CZ3-CG 4.35Å; W402-Y405 WeakPolarHBondContact O-CB 3.43Å; W402-Y405 PolarHBondContact O-N 2.92Å; Q403-Y405 VanDerWaalsContact C-N 3.33Å; Q403-Y405 PolarHBondContact O-N 3.22Å; Y405-R407 VanDerWaalsContact C-N 3.27Å; Y405-R407 PolarHBondContact O-N 2.99Å; Y405-R408 PolarHBondContact O-N 3.4Å; Y405-R408 VanDerWaalsContact O-N 3.16Å; Y405-V409 HydrophobicContact CD2-CB 4.49Å; Y405-V409 HydrophobicContact CD2-CG2 4.05Å; Y405-V409 HydrophobicContact CE2-CB 4.15Å; Y405-V409 HydrophobicContact CE2-CG2 3.71Å; Y405-V409 PolarHBondContact O-N 3.44Å
406C96.3Very high94.8Very high26 Ų2668.4 Ų68.418%0.17632%0.32CS..Hα-helixtrans-63.1-32.5178-64.80000112.7E391 W402 Q403 V409 P410E391-C406 PolarHBondContact OE1-SG 2.91Å; W402-C406 PolarHBondContact NE1-SG 3.07Å; W402-C406 VanDerWaalsContact NE1-SG 3.4Å; W402-C406 PolarHBondContact O-N 3.3Å; W402-C406 PolarHBondContact O-SG 3.4Å; Q403-C406 PolarHBondContact O-N 3.38Å; C406-V409 CarbonylContact O-C 3.48Å; C406-P410 VanDerWaalsContact O-CA 3.31Å; C406-P410 WeakPolarHBondContact O-CA 3.41Å
407R96.5Very high94.9Very high167 Ų16768 Ų6863%0.6332%0.321SS*.Hα-helixtrans-67.6-38.8175.2-167.4-171.368.380.93112Q403 E404 Y405Q403-R407 PolarHBondContact O-N 3.46Å; E404-R407 PolarHBondContact O-N 2.96Å; E404-R407 IonicContact OE1-CZ 3.7Å; E404-R407 IonicContact OE1-NE 3.38Å; E404-R407 IonicContact OE1-NH2 2.8Å; E404-R407 PolarHBondContact OE1-NH2 2.84Å; E404-R407 IonicContact OE2-CZ 3.48Å; E404-R407 IonicContact OE2-NE 3.07Å; E404-R407 PolarHBondContact OE2-NE 2.93Å; E404-R407 IonicContact OE2-NH2 3.3Å; E404-R407 PolarHBondContact OE2-NH2 2.93Å; Y405-R407 VanDerWaalsContact C-N 3.27Å; Y405-R407 PolarHBondContact O-N 2.99Å
408R96.4Very high95Very high114 Ų11467.6 Ų67.643%0.4332%0.317SS..Hα-helixtrans-77.8-37.4178.4-67.3-171.6-169.5-157.22.4112.8E327 E404 Y405 P410E327-R408 IonicContact OE2-NH1 3.71Å; E404-R408 PolarHBondContact O-N 3.38Å; E404-R408 VanDerWaalsContact O-N 3.1Å; E404-R408 IonicContact OE1-CZ 2.69Å; E404-R408 IonicContact OE1-NE 2.76Å; E404-R408 PolarHBondContact OE1-NE 3.08Å; E404-R408 IonicContact OE1-NH2 2.83Å; E404-R408 PolarHBondContact OE1-NH2 2.93Å; Y405-R408 PolarHBondContact O-N 3.4Å; Y405-R408 VanDerWaalsContact O-N 3.16Å; R408-P410 VanDerWaalsContact O-CD 3.31Å; R408-P410 WeakPolarHBondContact O-CD 3.49Å
409V96.9Very high95.1Very high1 Ų169.5 Ų69.51%0.00633%0.327CS..  trans-120.678.6-176.6-168.70000108V346 R347 Y405 C406 Y411V346-V409 VanDerWaalsContact C-CG1 3.46Å; R347-V409 HydrophobicContact CG-CB 4.11Å; R347-V409 HydrophobicContact CG-CG1 3.82Å; R347-V409 WeakPolarHBondContact CG-O 3.29Å; R347-V409 PolarHBondContact NH1-O 2.89Å; Y405-V409 HydrophobicContact CD2-CB 4.49Å; Y405-V409 HydrophobicContact CD2-CG2 4.05Å; Y405-V409 HydrophobicContact CE2-CB 4.15Å; Y405-V409 HydrophobicContact CE2-CG2 3.71Å; Y405-V409 PolarHBondContact O-N 3.44Å; C406-V409 CarbonylContact O-C 3.48Å; V409-Y411 VanDerWaalsContact C-N 3.35Å; V409-Y411 PolarHBondContact O-N 3.49Å
410P95.5Very high95.2Very high70 Ų7071.6 Ų71.646%0.45533%0.33SS..  trans-69.4-33.1-170.826.4-34.6000112.8R347 C406 R408R347-P410 PolarHBondContact NH1-O 3.42Å; C406-P410 VanDerWaalsContact O-CA 3.31Å; C406-P410 WeakPolarHBondContact O-CA 3.41Å; R408-P410 VanDerWaalsContact O-CD 3.31Å; R408-P410 WeakPolarHBondContact O-CD 3.49Å
411Y97.1Very high95.2Very high73 Ų7367.8 Ų67.829%0.28631%0.307SS..  trans-80.7135.9-176.6-52.7-60.3000112V346 R347 V409 Y416 Y418V346-Y411 CarbonylContact C-O 3.44Å; V346-Y411 WeakPolarHBondContact CA-O 3.43Å; R347-Y411 PolarHBondContact N-O 3.31Å; V409-Y411 VanDerWaalsContact C-N 3.35Å; V409-Y411 PolarHBondContact O-N 3.49Å; Y411-Y416 VanDerWaalsContact CD1-N 3.32Å; Y411-Y416 AromaticContact CE2-CD1 3.78Å; Y411-Y416 HydrophobicContact CE2-CD1 3.78Å; Y411-Y416 AromaticContact CE2-CE1 3.95Å; Y411-Y416 HydrophobicContact CE2-CE1 3.95Å; Y411-Y416 HydrophobicContact CE2-CG 4.29Å; Y411-Y416 AromaticContact CZ-CD1 3.62Å; Y411-Y416 WeakPolarHBondContact OH-CD1 3.33Å; Y411-Y418 WeakPolarHBondContact CA-O 3.38Å
412R95.4Very high95.2Very high73 Ų7371 Ų7128%0.27532%0.318SS..SBendtrans-85.8-56.9-174.5-67166.2176.5-127.27.9111.6R347 H348 E387 Y418R347-R412 PolarHBondContact N-O 2.93Å; R347-R412 VanDerWaalsContact NH2-CG 3.27Å; H348-R412 WeakPolarHBondContact CB-O 3.29Å; H348-R412 PolarHBondContact N-O 3.48Å; E387-R412 HydrophobicContact CG-CB 4.22Å; E387-R412 WeakPolarHBondContact OE1-CD 3.27Å; E387-R412 VanDerWaalsContact OE1-CG 3.25Å; E387-R412 WeakPolarHBondContact OE1-CG 3.44Å; E387-R412 IonicContact OE1-CZ 2.86Å; E387-R412 IonicContact OE1-NE 3.4Å; E387-R412 IonicContact OE1-NH1 2.71Å; E387-R412 PolarHBondContact OE1-NH1 2.87Å; E387-R412 IonicContact OE2-CZ 3.44Å; E387-R412 IonicContact OE2-NH1 2.77Å; E387-R412 PolarHBondContact OE2-NH1 3.37Å; R412-Y418 HydrophobicContact CB-CD1 3.75Å; R412-Y418 HydrophobicContact CB-CE1 3.62Å; R412-Y418 WeakPolarHBondContact CB-O 3.49Å; R412-Y418 VanDerWaalsContact CD-CE1 3.46Å; R412-Y418 WeakPolarHBondContact CD-OH 3.35Å; R412-Y418 HydrophobicContact CG-CE1 4.2Å; R412-Y418 VanDerWaalsContact N-C 3.3Å; R412-Y418 PolarHBondContact N-O 3.4Å; R412-Y418 PolarHBondContact N-OXT 3.32Å; R412-Y418 VanDerWaalsContact N-OXT 3.09Å; R412-Y418 PolarHBondContact NH1-OH 3.19Å
413I95.4Very high95.1Very high4 Ų474.6 Ų74.62%0.02134%0.335CS..SBendtrans-126.5-51.4-174.7-57.1176.9000110.4H348 Y351 L352 L355 V384 E387 Y418H348-I413 HydrophobicContact CB-CG1 4.32Å; Y351-I413 HydrophobicContact CD2-CD1 4.29Å; Y351-I413 HydrophobicContact CD2-CG1 4.43Å; L352-I413 HydrophobicContact CB-CG2 4.34Å; L355-I413 HydrophobicContact CD1-CG2 4.11Å; V384-I413 HydrophobicContact CG2-CD1 4.27Å; E387-I413 HydrophobicContact CB-CD1 4.27Å; E387-I413 HydrophobicContact CG-CG1 4.43Å; I413-Y418 HydrophobicContact CB-CD1 4.25Å; I413-Y418 HydrophobicContact CD1-CD1 4.36Å; I413-Y418 HydrophobicContact CD1-CE1 4.14Å; I413-Y418 HydrophobicContact CG1-CD1 4.22Å; I413-Y418 HydrophobicContact CG1-CE1 4.25Å; I413-Y418 PolarHBondContact N-OXT 2.97Å
414V94.3Very high95.1Very high43 Ų4372.3 Ų72.326%0.26132%0.323SS..SBendtrans-109.5115.5-172.6-173.70000108.5L352 Y416 I417 Y418L352-V414 HydrophobicContact CD1-CG2 4.29Å; V414-Y416 PolarHBondContact O-N 3Å; V414-I417 HydrophobicContact CB-CB 4.07Å; V414-I417 HydrophobicContact CG1-CB 3.88Å; V414-I417 HydrophobicContact CG1-CD1 3.71Å; V414-I417 HydrophobicContact CG1-CG1 4.12Å; V414-I417 PolarHBondContact O-N 3.45Å; V414-I417 VanDerWaalsContact O-N 3.1Å; V414-Y418 PolarHBondContact N-OXT 3.15Å; V414-Y418 PolarHBondContact O-N 2.94Å
415P91.3Very high95Very high34 Ų3473.6 Ų73.622%0.22133%0.329CS..THydrogen-bonded Turntrans-59.2137.7-175.526.7-34.1000109.9V346 I417V346-P415 HydrophobicContact CG1-CB 3.79Å; V346-P415 HydrophobicContact CG1-CG 4.28Å; P415-I417 PolarHBondContact O-N 3.09Å; P415-I417 VanDerWaalsContact O-N 3.15Å
416Y92.4Very high94.8Very high190 Ų19078.6 Ų78.675%0.74535%0.351SS*.THydrogen-bonded Turntrans65.65.1-179.3-47.3-77.6000116.2Y411 V414Y411-Y416 VanDerWaalsContact CD1-N 3.32Å; Y411-Y416 AromaticContact CE2-CD1 3.78Å; Y411-Y416 HydrophobicContact CE2-CD1 3.78Å; Y411-Y416 AromaticContact CE2-CE1 3.95Å; Y411-Y416 HydrophobicContact CE2-CE1 3.95Å; Y411-Y416 HydrophobicContact CE2-CG 4.29Å; Y411-Y416 AromaticContact CZ-CD1 3.62Å; Y411-Y416 WeakPolarHBondContact OH-CD1 3.33Å; V414-Y416 PolarHBondContact O-N 3Å
417I93.6Very high94.7Very high141 Ų14183 Ų8372%0.72337%0.366SS*.THydrogen-bonded Turntrans-124.4-55.7-178.8-63.2175.9000111.7V414 P415V414-I417 HydrophobicContact CB-CB 4.07Å; V414-I417 HydrophobicContact CG1-CB 3.88Å; V414-I417 HydrophobicContact CG1-CD1 3.71Å; V414-I417 HydrophobicContact CG1-CG1 4.12Å; V414-I417 PolarHBondContact O-N 3.45Å; V414-I417 VanDerWaalsContact O-N 3.1Å; P415-I417 PolarHBondContact O-N 3.09Å; P415-I417 VanDerWaalsContact O-N 3.15Å
418Y91.8Very high94.5Very high86 Ų8675.4 Ų75.434%0.33734%0.342SS..  trans-146.50-176.4178-98.1000110V384 E387 Y411 R412 I413 V414V384-Y418 HydrophobicContact CG2-CE1 4.46Å; E387-Y418 PolarHBondContact OE2-OH 2.99Å; Y411-Y418 WeakPolarHBondContact CA-O 3.38Å; R412-Y418 HydrophobicContact CB-CD1 3.75Å; R412-Y418 HydrophobicContact CB-CE1 3.62Å; R412-Y418 WeakPolarHBondContact CB-O 3.49Å; R412-Y418 VanDerWaalsContact CD-CE1 3.46Å; R412-Y418 WeakPolarHBondContact CD-OH 3.35Å; R412-Y418 HydrophobicContact CG-CE1 4.2Å; R412-Y418 VanDerWaalsContact N-C 3.3Å; R412-Y418 PolarHBondContact N-O 3.4Å; R412-Y418 PolarHBondContact N-OXT 3.32Å; R412-Y418 VanDerWaalsContact N-OXT 3.09Å; R412-Y418 PolarHBondContact NH1-OH 3.19Å; I413-Y418 HydrophobicContact CB-CD1 4.25Å; I413-Y418 HydrophobicContact CD1-CD1 4.36Å; I413-Y418 HydrophobicContact CD1-CE1 4.14Å; I413-Y418 HydrophobicContact CG1-CD1 4.22Å; I413-Y418 HydrophobicContact CG1-CE1 4.25Å; I413-Y418 PolarHBondContact N-OXT 2.97Å; V414-Y418 PolarHBondContact N-OXT 3.15Å; V414-Y418 PolarHBondContact O-N 2.94Å

Retrieved 418 of 418 residues in 400.3 ms (Link to these results)

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