A0A096MNY1_PAPAN Loading...

Granzyme A

AlphaFold DB , UniProt , Accession A0A096MNY1, Species PAPAN (Papio anubis, Olive baboon), Gene GZMA, Length 262 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M41.4Very low46.6Very low244 Ų244168.7 Ų168.7100%1.20285%0.851SS**  0115.60-78.2173.6-104.200107.9
2R41.6Very low47Very low241 Ų241167 Ų16791%0.90985%0.845SS**  trans-60133175.6-85.4167.7163166-6.2109.1
3N38.3Very low47.7Very low146 Ų146162.4 Ų162.478%0.78184%0.838SS**  trans-139.9117.1154.7-129.91.3000109.9
4S46.1Very low48.2Very low100 Ų100159.1 Ų159.170%0.69983%0.828SS**  trans-94.1106-166.1-42.50000108.9R6S4-R6 PolarHBondContact O-N 3.46Å
5Y47.2Very low48.7Very low205 Ų205155.3 Ų155.380%0.80481%0.814SS**  trans-84106.3169.2-80.4-84.8000109.3F7Y5-F7 PolarHBondContact O-N 2.91Å
6R46.4Very low49.2Very low235 Ų235152.5 Ų152.589%0.88781%0.805SS**  trans-71.4110.6170.4-70.6-178175.1-172.3-1.5108.4S4 L8S4-R6 PolarHBondContact O-N 3.46Å; R6-L8 PolarHBondContact O-N 3.44Å
7F45.3Very low49.2Very low203 Ų203153.8 Ų153.889%0.8980%0.803SS**  trans-77.4109.7164.3-88.7-91.6000108.6Y5 A9Y5-F7 PolarHBondContact O-N 2.91Å; F7-A9 PolarHBondContact O-N 3.34Å
8L49.7Very low49.1Very low171 Ų171153.5 Ų153.590%0.89580%0.801SS**  trans-7698.6164.3-90.3138.7000107.7R6 S10R6-L8 PolarHBondContact O-N 3.44Å; L8-S10 PolarHBondContact O-N 2.96Å
9A49.7Very low49Very low96 Ų96151.3 Ų151.379%0.79380%0.795SS**  trans-75.2103.6169.100000108.7F7 S11F7-A9 PolarHBondContact O-N 3.34Å; A9-S11 PolarHBondContact O-N 3.12Å
10S51.5Low49Very low102 Ų102151.6 Ų151.671%0.71380%0.796SS**  trans-76.2101.4168.9168.90000108.9L8 L12L8-S10 PolarHBondContact O-N 2.96Å; S10-L12 PolarHBondContact O-N 3.14Å
11S55.3Low49.2Very low113 Ų113150.7 Ų150.779%0.7979%0.791SS**  trans-80.5100.5169.551.80000109.9A9 S13A9-S11 PolarHBondContact O-N 3.12Å; S11-S13 PolarHBondContact O-N 3.22Å; S11-S13 VanDerWaalsContact O-N 3.14Å
12L51.4Low49.4Very low148 Ų148144.1 Ų144.178%0.77577%0.766SS**  trans-71.4103.4161.4-103.187.6000107.8S10 V14S10-L12 PolarHBondContact O-N 3.14Å; L12-V14 PolarHBondContact O-N 3.39Å; L12-V14 VanDerWaalsContact O-N 3.17Å
13S55.8Low49.5Very low107 Ų107140.6 Ų140.675%0.74876%0.76SS**  trans-74.2100.7169.5-160.10000108.4S11 V15S11-S13 PolarHBondContact O-N 3.22Å; S11-S13 VanDerWaalsContact O-N 3.14Å; S13-V15 PolarHBondContact O-N 2.82Å; S13-V15 VanDerWaalsContact O-N 3.16Å
14V55.5Low49.7Very low117 Ų117140.6 Ų140.671%0.70976%0.76SS**  trans-76.997.9171.3-178.90000107.2L12 V16L12-V14 PolarHBondContact O-N 3.39Å; L12-V14 VanDerWaalsContact O-N 3.17Å; V14-V16 HydrophobicContact CG1-CG2 4.1Å; V14-V16 PolarHBondContact O-N 3.28Å; V14-V16 VanDerWaalsContact O-N 3.08Å
15V56.2Low49.5Very low102 Ų102140.7 Ų140.762%0.61876%0.756SS**  trans-74.996.3170.5-175.90000107.3S13 F17S13-V15 PolarHBondContact O-N 2.82Å; S13-V15 VanDerWaalsContact O-N 3.16Å; V15-F17 HydrophobicContact CG1-CD2 3.79Å; V15-F17 HydrophobicContact CG1-CE2 3.81Å; V15-F17 PolarHBondContact O-N 3.1Å
16V55.3Low49.1Very low110 Ų110135.5 Ų135.567%0.66775%0.749SS**  trans-71.496.9167-179.30000106.7V14 L18V14-V16 HydrophobicContact CG1-CG2 4.1Å; V14-V16 PolarHBondContact O-N 3.28Å; V14-V16 VanDerWaalsContact O-N 3.08Å; V16-L18 VanDerWaalsContact C-N 3.26Å; V16-L18 HydrophobicContact CG1-CG 4.46Å; V16-L18 PolarHBondContact O-N 2.66Å
17F50Low48.8Very low175 Ų175130.5 Ų130.577%0.76874%0.735SS**  trans-66.495.7161.5-92.9-88000106.9V15 V19V15-F17 HydrophobicContact CG1-CD2 3.79Å; V15-F17 HydrophobicContact CG1-CE2 3.81Å; V15-F17 PolarHBondContact O-N 3.1Å; F17-V19 PolarHBondContact O-N 2.97Å
18L47.8Very low48.6Very low148 Ų148121.8 Ų121.878%0.77570%0.697SS**  trans-61.491.7157.3-87.5154.7000106V16 L20V16-L18 VanDerWaalsContact C-N 3.26Å; V16-L18 HydrophobicContact CG1-CG 4.46Å; V16-L18 PolarHBondContact O-N 2.66Å; L18-L20 PolarHBondContact O-N 3.24Å
19V47.3Very low48.9Very low112 Ų112113.7 Ų113.768%0.67966%0.655SS**  trans-63.493.3163.2-178.70000104.7F17 I21F17-V19 PolarHBondContact O-N 2.97Å; V19-I21 HydrophobicContact CG1-CG1 3.97Å; V19-I21 PolarHBondContact O-N 2.78Å
20L49.1Very low50Low157 Ų157110 Ų11082%0.82262%0.622SS**  trans-62.889.2159-78.1159.1000104.8L18 P22L18-L20 PolarHBondContact O-N 3.24Å; L20-P22 WeakPolarHBondContact O-CD 3.47Å; L20-P22 VanDerWaalsContact O-N 3.16Å
21I52.9Low51.4Low133 Ų133105.9 Ų105.968%0.68260%0.595SS**  trans-60.6113.2159.1-55.4177.6000103V19 E23V19-I21 HydrophobicContact CG1-CG1 3.97Å; V19-I21 PolarHBondContact O-N 2.78Å; I21-E23 PolarHBondContact O-N 3.46Å
22P44.7Very low52.9Low105 Ų105100.6 Ų100.668%0.68256%0.559SS**  trans-61.8112.5166.726.1-25.7000104.5L20 D24L20-P22 WeakPolarHBondContact O-CD 3.47Å; L20-P22 VanDerWaalsContact O-N 3.16Å; P22-D24 VanDerWaalsContact C-N 3.27Å; P22-D24 PolarHBondContact O-N 3.28Å
23E45Very low54.8Low167 Ų16798.7 Ų98.778%0.7855%0.549SS*.  trans-57.7106.5160.4-74.9-167.7161.700104.8I21 V25I21-E23 PolarHBondContact O-N 3.46Å; E23-V25 HydrophobicContact CB-CG2 4.23Å; E23-V25 WeakPolarHBondContact O-CG2 3.49Å; E23-V25 PolarHBondContact O-N 2.87Å
24D42.1Very low56.7Low147 Ų14798 Ų9879%0.78653%0.534SS*.  trans-59.789.4164.3-107.9-25.1000105.8P22 C26P22-D24 VanDerWaalsContact C-N 3.27Å; P22-D24 PolarHBondContact O-N 3.28Å; D24-C26 PolarHBondContact O-N 3.16Å
25V41.7Very low58.7Low102 Ų10293 Ų9362%0.61850%0.504SS*.  trans-7678.3173.9-172.30000106.9E23 E27E23-V25 HydrophobicContact CB-CG2 4.23Å; E23-V25 WeakPolarHBondContact O-CG2 3.49Å; E23-V25 PolarHBondContact O-N 2.87Å; V25-E27 HydrophobicContact CG1-CB 4.37Å; V25-E27 HydrophobicContact CG1-CG 3.99Å; V25-E27 PolarHBondContact O-N 3.42Å
26C39.3Very low60.7Low95 Ų9593.2 Ų93.264%0.64251%0.505SS*.  trans-8285.1166.1-67.70000108.6D24D24-C26 PolarHBondContact O-N 3.16Å
27E39.8Very low62.7Low130 Ų13091.3 Ų91.361%0.60750%0.495SS*.  trans-111.5141.1173-78.5-168.7173.700112.4V25 I156V25-E27 HydrophobicContact CG1-CB 4.37Å; V25-E27 HydrophobicContact CG1-CG 3.99Å; V25-E27 PolarHBondContact O-N 3.42Å; E27-I156 WeakPolarHBondContact O-CD1 3.28Å
28E40.3Very low65Low20 Ų2084.3 Ų84.39%0.09347%0.465CS..  cis159.4149.2-22.3-99.3-163.3146.400107.2I30 G31 G32 N33 I156E28-I30 PolarHBondContact O-N 3.39Å; E28-I30 VanDerWaalsContact O-N 3.11Å; E28-G31 WeakPolarHBondContact OE2-CA 3.31Å; E28-G32 CarbonylContact C-O 3.58Å; E28-G32 WeakPolarHBondContact CA-O 3.31Å; E28-G32 WeakPolarHBondContact CB-O 3.13Å; E28-G32 VanDerWaalsContact CD-O 3.3Å; E28-G32 VanDerWaalsContact CG-C 3.42Å; E28-G32 WeakPolarHBondContact CG-O 3.41Å; E28-G32 WeakPolarHBondContact OE1-CA 3.28Å; E28-G32 PolarHBondContact OE2-N 3.32Å; E28-N33 WeakPolarHBondContact OE1-CA 3.48Å; E28-N33 PolarHBondContact OE1-N 3.24Å; E28-N33 VanDerWaalsContact OE1-N 3.14Å; E28-N33 PolarHBondContact OE1-ND2 3.29Å; E28-N33 PolarHBondContact OE1-OD1 3.39Å; E28-I156 VanDerWaalsContact C-CB 3.48Å; E28-I156 CarbonylContact O-C 3.49Å; E28-I156 WeakPolarHBondContact O-CA 3.16Å; E28-I156 WeakPolarHBondContact O-CB 3.48Å; E28-I156 VanDerWaalsContact O-CG2 3.26Å; E28-I156 WeakPolarHBondContact O-CG2 3.11Å
29I55.8Low67.4Low1 Ų179.2 Ų79.21%0.00544%0.442CS..BIsolated β-bridgetrans-50127.8155.4-86.8-86.7000103.6G31 G32 R167 V169 D206 D211I29-G31 CarbonylContact O-C 3.44Å; I29-G31 PolarHBondContact O-N 2.85Å; I29-G32 PolarHBondContact N-O 3.14Å; I29-G32 VanDerWaalsContact N-O 3.11Å; I29-G32 VanDerWaalsContact O-CA 3.32Å; I29-G32 WeakPolarHBondContact O-CA 3.4Å; I29-G32 PolarHBondContact O-N 3.16Å; I29-R167 HydrophobicContact CB-CB 3.97Å; I29-R167 HydrophobicContact CG1-CB 3.4Å; I29-R167 HydrophobicContact CG1-CG 4.24Å; I29-R167 VanDerWaalsContact N-CD 3.32Å; I29-V169 HydrophobicContact CG2-CB 3.94Å; I29-V169 HydrophobicContact CG2-CG1 3.67Å; I29-D206 WeakPolarHBondContact CG2-O 3.27Å; I29-D211 VanDerWaalsContact CD1-OD1 3.25Å; I29-D211 WeakPolarHBondContact CD1-OD1 3.37Å; I29-D211 WeakPolarHBondContact CD1-OD2 3.43Å
30I73.5Confident69.9Low20 Ų2077.1 Ų77.110%0.10342%0.422CS..THydrogen-bonded Turntrans-40.6105.9-157.5-57.4-166.8000112.2E28 G204 K205 D206 C234E28-I30 PolarHBondContact O-N 3.39Å; E28-I30 VanDerWaalsContact O-N 3.11Å; I30-G204 CarbonylContact C-O 3.59Å; I30-K205 WeakPolarHBondContact O-CA 3.45Å; I30-D206 PolarHBondContact O-N 2.77Å; I30-D206 VanDerWaalsContact O-N 3.09Å; I30-C234 VanDerWaalsContact CD1-C 3.5Å; I30-C234 HydrophobicContact CD1-CB 3.27Å; I30-C234 WeakPolarHBondContact CD1-O 3.36Å; I30-C234 HydrophobicContact CG1-CB 4.35Å
31G79.9Confident72.2Confident15 Ų1571 Ų7116%0.15539%0.391CS..THydrogen-bonded Turntrans7520.9-176.100000118.9E28 I29 V169 G204E28-G31 WeakPolarHBondContact OE2-CA 3.31Å; I29-G31 CarbonylContact O-C 3.44Å; I29-G31 PolarHBondContact O-N 2.85Å; G31-V169 WeakPolarHBondContact O-CG2 3.2Å; G31-G204 WeakPolarHBondContact CA-O 3.34Å; G31-G204 PolarHBondContact N-O 2.77Å
32G86.8Confident74.4Confident2 Ų265.9 Ų65.92%0.02136%0.364CS..BIsolated β-bridgetrans-137.8143.4-177.500000116.5E28 I29 R167 E168E28-G32 CarbonylContact C-O 3.58Å; E28-G32 WeakPolarHBondContact CA-O 3.31Å; E28-G32 WeakPolarHBondContact CB-O 3.13Å; E28-G32 VanDerWaalsContact CD-O 3.3Å; E28-G32 VanDerWaalsContact CG-C 3.42Å; E28-G32 WeakPolarHBondContact CG-O 3.41Å; E28-G32 WeakPolarHBondContact OE1-CA 3.28Å; E28-G32 PolarHBondContact OE2-N 3.32Å; I29-G32 PolarHBondContact N-O 3.14Å; I29-G32 VanDerWaalsContact N-O 3.11Å; I29-G32 VanDerWaalsContact O-CA 3.32Å; I29-G32 WeakPolarHBondContact O-CA 3.4Å; I29-G32 PolarHBondContact O-N 3.16Å; G32-R167 PolarHBondContact O-NE 3.25Å; G32-R167 VanDerWaalsContact O-NE 3.1Å; G32-E168 CarbonylContact C-O 3.38Å; G32-E168 VanDerWaalsContact C-O 3.25Å; G32-E168 WeakPolarHBondContact CA-O 3.42Å
33N91.9Very high77Confident107 Ų10761.1 Ų61.157%0.57233%0.332SS*.EExtended strand (participates in β ladder)trans-86.6160.7-165.3-71.8-101.5000113.5E28 V35 R167 E168E28-N33 WeakPolarHBondContact OE1-CA 3.48Å; E28-N33 PolarHBondContact OE1-N 3.24Å; E28-N33 VanDerWaalsContact OE1-N 3.14Å; E28-N33 PolarHBondContact OE1-ND2 3.29Å; E28-N33 PolarHBondContact OE1-OD1 3.39Å; N33-V35 PolarHBondContact O-N 3.37Å; N33-R167 CarbonylContact O-C 3.58Å; N33-R167 WeakPolarHBondContact O-CA 3.42Å; N33-R167 VanDerWaalsContact O-CB 3.31Å; N33-R167 WeakPolarHBondContact O-CB 3.23Å; N33-E168 PolarHBondContact N-O 3.11Å; N33-E168 PolarHBondContact O-N 2.86Å
34E95.4Very high79.6Confident92 Ų9253.2 Ų53.243%0.4330%0.295SS..EExtended strand (participates in β ladder)trans-61.2131.9165.4179.1167.3159.200109.6H83 T165 R167E34-H83 IonicContact OE1-CD2 2.79Å; E34-H83 IonicContact OE1-CE1 3.26Å; E34-H83 IonicContact OE1-NE2 3.52Å; E34-H83 PolarHBondContact OE1-NE2 2.93Å; E34-T165 VanDerWaalsContact CD-OG1 3.25Å; E34-T165 PolarHBondContact OE2-OG1 2.76Å; E34-R167 VanDerWaalsContact N-CZ 3.27Å; E34-R167 VanDerWaalsContact N-NH2 3.17Å
35V96.9Very high82.3Confident12 Ų1246.2 Ų46.27%0.07326%0.258CS..PPolyproline II helixtrans-79.9154.9176.3-570000110.2N33 H83 L166 E168N33-V35 PolarHBondContact O-N 3.37Å; V35-H83 PolarHBondContact O-CE1 2.95Å; V35-L166 HydrophobicContact CG2-CB 3.9Å; V35-L166 HydrophobicContact CG2-CD2 3.78Å; V35-L166 HydrophobicContact CG2-CG 3.7Å; V35-L166 WeakPolarHBondContact CG2-O 3.4Å; V35-L166 PolarHBondContact N-O 3.27Å; V35-L166 VanDerWaalsContact N-O 3.08Å; V35-E168 HydrophobicContact CG1-CB 3.43Å; V35-E168 VanDerWaalsContact CG1-CB 3.43Å
36T98.3Very high85Confident107 Ų10741.4 Ų41.466%0.65623%0.229SC*.PPolyproline II helixtrans-54.7132.5166.6-53.60000109.2H38 S39T36-H38 PolarHBondContact O-N 3.09Å; T36-S39 WeakPolarHBondContact O-CB 3.47Å; T36-S39 PolarHBondContact O-N 2.69Å; T36-S39 PolarHBondContact O-OG 2.99Å
37P98.5Very high87.7Confident70 Ų7038.8 Ų38.846%0.45521%0.212SC..THydrogen-bonded Turntrans-48.7130.3-177.2-30.434000113.1S39 H83P37-S39 PolarHBondContact O-N 3.02Å; P37-S39 VanDerWaalsContact O-N 3.1Å; P37-H83 HydrophobicContact CB-CB 4.13Å
38H98.3Very high90.2Very high28 Ų2833.3 Ų33.313%0.1319%0.187CC..THydrogen-bonded Turntrans59.914.9180-40.8-72.3000115.7T36 R40 G81 E89 Y129T36-H38 PolarHBondContact O-N 3.09Å; H38-R40 PolarHBondContact O-N 2.74Å; H38-G81 PolarHBondContact CE1-O 3.09Å; H38-G81 PolarHBondContact ND1-O 2.8Å; H38-E89 IonicContact CE1-OE2 3.76Å; H38-Y129 HydrophobicContact CB-CD1 3.6Å; H38-Y129 HydrophobicContact CB-CE1 4.43Å; H38-Y129 HydrophobicContact CB-CG 4.32Å; H38-Y129 AromaticContact CG-CD1 3.96Å
39S98.6Very high92.3Very high42 Ų4237.4 Ų37.429%0.29421%0.205SC..SBendtrans-74.3-3.2177.466.10000114.4T36 P37 P41T36-S39 WeakPolarHBondContact O-CB 3.47Å; T36-S39 PolarHBondContact O-N 2.69Å; T36-S39 PolarHBondContact O-OG 2.99Å; P37-S39 PolarHBondContact O-N 3.02Å; P37-S39 VanDerWaalsContact O-N 3.1Å; S39-P41 WeakPolarHBondContact O-CD 3.4Å
40R98.8Very high93.3Very high68 Ų6840.1 Ų40.126%0.25723%0.234SC..SBendtrans-124.166.2172.6-58.7-64.4-179.1-83.1-4.9110H38 Y42 M43 L166 E168H38-R40 PolarHBondContact O-N 2.74Å; R40-Y42 WeakPolarHBondContact CD-OH 3.22Å; R40-Y42 PolarHBondContact O-N 3.26Å; R40-M43 HydrophobicContact CB-CG 3.71Å; R40-M43 WeakPolarHBondContact O-CB 3.38Å; R40-M43 WeakPolarHBondContact O-CG 3.3Å; R40-M43 PolarHBondContact O-N 2.97Å; R40-L166 HydrophobicContact CB-CD2 3.99Å; R40-L166 HydrophobicContact CG-CD2 4.47Å; R40-E168 IonicContact CZ-OE1 3.63Å; R40-E168 IonicContact CZ-OE2 3.39Å; R40-E168 IonicContact NE-OE1 3.71Å; R40-E168 IonicContact NE-OE2 2.69Å; R40-E168 PolarHBondContact NE-OE2 2.76Å; R40-E168 VanDerWaalsContact NH2-CD 3.32Å; R40-E168 IonicContact NH2-OE1 2.68Å; R40-E168 PolarHBondContact NH2-OE1 3.3Å; R40-E168 IonicContact NH2-OE2 2.71Å; R40-E168 PolarHBondContact NH2-OE2 2.71Å
41P98.8Very high93.4Very high27 Ų2747.9 Ų47.918%0.17527%0.267CS..THydrogen-bonded Turntrans-68.7-4.8-166.524.9-32.8000115.2S39 Y129 V130 T131S39-P41 WeakPolarHBondContact O-CD 3.4Å; P41-Y129 WeakPolarHBondContact CA-O 3.33Å; P41-Y129 VanDerWaalsContact CB-O 3.28Å; P41-Y129 WeakPolarHBondContact CB-O 3.5Å; P41-V130 CarbonylContact O-C 3.54Å; P41-V130 VanDerWaalsContact O-CA 3.31Å; P41-V130 WeakPolarHBondContact O-CA 3.3Å; P41-T131 HydrophobicContact CB-CG2 3.85Å; P41-T131 HydrophobicContact CG-CG2 3.74Å; P41-T131 VanDerWaalsContact CG-OG1 3.31Å; P41-T131 WeakPolarHBondContact CG-OG1 3.11Å; P41-T131 PolarHBondContact O-N 3.3Å
42Y98.9Very high93.8Very high27 Ų2750.9 Ų50.911%0.10628%0.282CS..THydrogen-bonded Turntrans-90.4-9.7173.453.6-100.3000114.3R40 L58 T131 L133 P215 L217R40-Y42 WeakPolarHBondContact CD-OH 3.22Å; R40-Y42 PolarHBondContact O-N 3.26Å; Y42-L58 PolarHBondContact O-N 3.2Å; Y42-T131 VanDerWaalsContact CA-O 3.27Å; Y42-T131 WeakPolarHBondContact CA-O 3.27Å; Y42-T131 WeakPolarHBondContact CB-O 3.37Å; Y42-T131 PolarHBondContact N-OG1 2.81Å; Y42-L133 HydrophobicContact CD1-CD1 4.19Å; Y42-L133 HydrophobicContact CD2-CB 4.23Å; Y42-L133 HydrophobicContact CD2-CD1 4.48Å; Y42-L133 HydrophobicContact CD2-CD2 3.88Å; Y42-L133 HydrophobicContact CD2-CG 4.44Å; Y42-L133 HydrophobicContact CE1-CD1 4.38Å; Y42-L133 HydrophobicContact CE2-CD2 4.18Å; Y42-L133 HydrophobicContact CG-CB 3.88Å; Y42-L133 HydrophobicContact CG-CD1 4.23Å; Y42-L133 HydrophobicContact CG-CD2 4.31Å; Y42-L133 HydrophobicContact CG-CG 4.38Å; Y42-P215 HydrophobicContact CD2-CG 4.11Å; Y42-P215 HydrophobicContact CE2-CG 3.82Å; Y42-L217 HydrophobicContact CE1-CD1 4.33Å; Y42-L217 HydrophobicContact CE2-CD1 4.5Å; Y42-L217 WeakPolarHBondContact OH-CD1 3.46Å
43M98.9Very high94.2Very high5 Ų551.2 Ų51.23%0.02528%0.283CS..EExtended strand (participates in β ladder)trans-67.7139.5-178.5-73.7-61.4-62.500110.8R40 A55 A151 W153 L166 P215R40-M43 HydrophobicContact CB-CG 3.71Å; R40-M43 WeakPolarHBondContact O-CB 3.38Å; R40-M43 WeakPolarHBondContact O-CG 3.3Å; R40-M43 PolarHBondContact O-N 2.97Å; M43-A55 HydrophobicContact CE-CB 4.15Å; M43-A151 HydrophobicContact CE-CB 4.27Å; M43-A151 WeakPolarHBondContact CE-O 2.99Å; M43-A151 HydrophobicContact CG-CB 4.48Å; M43-A151 HydrophobicContact SD-CB 4.17Å; M43-W153 HydrophobicContact CB-CH2 3.92Å; M43-W153 HydrophobicContact CB-CZ3 4.26Å; M43-W153 HydrophobicContact CE-CZ3 4.01Å; M43-L166 HydrophobicContact CB-CD2 4.22Å; M43-L166 HydrophobicContact CE-CD1 4.23Å; M43-L166 HydrophobicContact CG-CD1 4.49Å; M43-L166 HydrophobicContact CG-CD2 4.07Å; M43-P215 HydrophobicContact SD-CG 3.67Å
44V98.9Very high94.5Very high0 Ų046.4 Ų46.40%026%0.258CS..EExtended strand (participates in β ladder)trans-119.6126.1177.5-176.60000108.5L46 A55 G56 L58 V64 V78 L80V44-L46 HydrophobicContact CG1-CD2 3.89Å; V44-A55 CarbonylContact O-C 3.35Å; V44-A55 VanDerWaalsContact O-CA 3.26Å; V44-A55 WeakPolarHBondContact O-CA 3.33Å; V44-G56 WeakPolarHBondContact CB-O 3.36Å; V44-G56 PolarHBondContact N-O 3.34Å; V44-G56 PolarHBondContact O-N 2.93Å; V44-L58 HydrophobicContact CG2-CB 4.05Å; V44-V64 HydrophobicContact CB-CG1 4.15Å; V44-V64 HydrophobicContact CG1-CG1 3.99Å; V44-V64 HydrophobicContact CG1-CG2 4.22Å; V44-V64 HydrophobicContact CG2-CG1 4.02Å; V44-V64 HydrophobicContact CG2-CG2 4.06Å; V44-V78 HydrophobicContact CG1-CG1 3.52Å; V44-L80 HydrophobicContact CB-CD2 4.21Å; V44-L80 HydrophobicContact CG1-CD2 3.93Å; V44-L80 HydrophobicContact CG2-CD2 3.54Å
45L98.7Very high94.7Very high0 Ų042 Ų420%024%0.237CC..EExtended strand (participates in β ladder)trans-91.3121.6168.7170.464.6000108.7I53 I79 I85 W153L45-I53 HydrophobicContact CD1-CB 4.18Å; L45-I53 HydrophobicContact CD1-CD1 4.35Å; L45-I53 HydrophobicContact CD1-CG2 4.3Å; L45-I79 HydrophobicContact CB-CB 4.21Å; L45-I79 HydrophobicContact CD2-CD1 4.06Å; L45-I79 HydrophobicContact CG-CD1 4.45Å; L45-I79 PolarHBondContact N-O 2.93Å; L45-I79 PolarHBondContact O-N 3Å; L45-I85 HydrophobicContact CD1-CG1 4.49Å; L45-I85 HydrophobicContact CD2-CB 4.39Å; L45-I85 HydrophobicContact CD2-CG1 3.91Å; L45-I85 HydrophobicContact CD2-CG2 4.36Å; L45-W153 HydrophobicContact CB-CD2 4.46Å; L45-W153 HydrophobicContact CB-CE3 4.06Å; L45-W153 HydrophobicContact CB-CH2 3.98Å; L45-W153 HydrophobicContact CB-CZ2 4.38Å; L45-W153 HydrophobicContact CB-CZ3 3.8Å; L45-W153 HydrophobicContact CD1-CD2 4.12Å; L45-W153 HydrophobicContact CD1-CE3 3.98Å; L45-W153 HydrophobicContact CD1-CG 4.37Å
46L98.5Very high94.7Very high1 Ų141.4 Ų41.41%0.00523%0.234CC..EExtended strand (participates in β ladder)trans-98.2105.2171.2-57.2-179.2000108.5V44 L48 I53 C54 T66 V78 L118V44-L46 HydrophobicContact CG1-CD2 3.89Å; L46-L48 HydrophobicContact CB-CD2 4.06Å; L46-L48 HydrophobicContact CB-CG 4.49Å; L46-L48 PolarHBondContact O-N 3.29Å; L46-I53 CarbonylContact O-C 3.58Å; L46-I53 WeakPolarHBondContact O-CA 3.37Å; L46-C54 WeakPolarHBondContact CA-O 3.49Å; L46-C54 HydrophobicContact CB-CB 3.98Å; L46-C54 WeakPolarHBondContact CB-O 3.49Å; L46-C54 HydrophobicContact CD1-CB 3.92Å; L46-C54 HydrophobicContact CG-CB 4.41Å; L46-C54 PolarHBondContact N-O 2.83Å; L46-C54 PolarHBondContact O-N 3.42Å; L46-T66 HydrophobicContact CD1-CG2 3.94Å; L46-T66 VanDerWaalsContact CD1-OG1 3.28Å; L46-T66 WeakPolarHBondContact CD1-OG1 3.17Å; L46-V78 HydrophobicContact CD2-CB 4.33Å; L46-V78 HydrophobicContact CD2-CG1 4.31Å; L46-V78 HydrophobicContact CD2-CG2 3.78Å; L46-L118 HydrophobicContact CD1-CD1 4.21Å; L46-L118 HydrophobicContact CD2-CD1 3.9Å
47S96.3Very high94.8Very high41 Ų4136.3 Ų36.329%0.28720%0.203SC..EExtended strand (participates in β ladder)trans-85.6108172.9177.90000108.8S76 Q77S47-S76 CarbonylContact O-C 3.25Å; S47-S76 VanDerWaalsContact O-CA 3.23Å; S47-S76 WeakPolarHBondContact O-CA 3.3Å; S47-Q77 PolarHBondContact N-O 2.93Å; S47-Q77 PolarHBondContact O-N 2.85Å
48L92.8Very high94.8Very high15 Ų1533 Ų338%0.07918%0.181CC..  trans-101176.1-175.5-49.3179.5000111.4L46 T52 C54 C70 L72L46-L48 HydrophobicContact CB-CD2 4.06Å; L46-L48 HydrophobicContact CB-CG 4.49Å; L46-L48 PolarHBondContact O-N 3.29Å; L48-T52 CarbonylContact C-O 3.51Å; L48-T52 WeakPolarHBondContact CA-O 3.49Å; L48-T52 VanDerWaalsContact CB-O 3.27Å; L48-T52 WeakPolarHBondContact CB-O 3.39Å; L48-T52 HydrophobicContact CD1-CG2 4.31Å; L48-T52 PolarHBondContact N-O 3.08Å; L48-C54 HydrophobicContact CD1-CB 4.14Å; L48-C70 HydrophobicContact CD1-CB 4.4Å; L48-L72 HydrophobicContact CD2-CD1 4.07Å; L48-L72 HydrophobicContact CD2-CG 3.77Å
49H83.3Confident94.8Very high105 Ų10532.4 Ų32.449%0.48618%0.179SC..G310 helixtrans-60.3147.6176.6-175.7-114.3000112.6K51 T52 D73 R75H49-K51 VanDerWaalsContact C-N 3.34Å; H49-K51 PolarHBondContact O-N 2.89Å; H49-T52 PolarHBondContact O-N 3.17Å; H49-T52 PolarHBondContact O-OG1 2.83Å; H49-D73 WeakPolarHBondContact CB-OD2 3.44Å; H49-D73 IonicContact CD2-OD2 3.4Å; H49-D73 IonicContact CG-OD2 3.95Å; H49-R75 PolarHBondContact CD2-NH2 3.15Å; H49-R75 PolarHBondContact NE2-NH2 3.31Å
50G76.9Confident94.8Very high58 Ų5831.5 Ų31.560%0.59817%0.174SC*.G310 helixtrans7322.1171.700000114.9T52G50-T52 PolarHBondContact O-N 2.85Å
51K76.3Confident94.8Very high183 Ų18331.7 Ų31.780%0.79618%0.178SC*.G310 helixtrans64.116-172.7-51.2179.1178-1790113.8H49 Q162H49-K51 VanDerWaalsContact C-N 3.34Å; H49-K51 PolarHBondContact O-N 2.89Å; K51-Q162 PolarHBondContact O-NE2 3.22Å; K51-Q162 PolarHBondContact O-OE1 3.2Å
52T88.2Confident94.8Very high78 Ų7832.1 Ų32.148%0.47918%0.178SC..  trans-73.6144.7166.8-55.50000108.7L48 H49 G50L48-T52 CarbonylContact C-O 3.51Å; L48-T52 WeakPolarHBondContact CA-O 3.49Å; L48-T52 VanDerWaalsContact CB-O 3.27Å; L48-T52 WeakPolarHBondContact CB-O 3.39Å; L48-T52 HydrophobicContact CD1-CG2 4.31Å; L48-T52 PolarHBondContact N-O 3.08Å; H49-T52 PolarHBondContact O-N 3.17Å; H49-T52 PolarHBondContact O-OG1 2.83Å; G50-T52 PolarHBondContact O-N 2.85Å
53I95.3Very high94.8Very high9 Ų930.9 Ų30.95%0.04617%0.173CC..EExtended strand (participates in β ladder)trans-127.7156.7173.767.3179.7000109.7L45 L46 I85 W153 Q162 G210L45-I53 HydrophobicContact CD1-CB 4.18Å; L45-I53 HydrophobicContact CD1-CD1 4.35Å; L45-I53 HydrophobicContact CD1-CG2 4.3Å; L46-I53 CarbonylContact O-C 3.58Å; L46-I53 WeakPolarHBondContact O-CA 3.37Å; I53-I85 HydrophobicContact CD1-CD1 3.95Å; I53-W153 HydrophobicContact CD1-CB 3.68Å; I53-W153 WeakPolarHBondContact CD1-O 3.34Å; I53-Q162 HydrophobicContact CD1-CB 4Å; I53-Q162 HydrophobicContact CD1-CG 3.77Å; I53-Q162 HydrophobicContact CG1-CG 4.09Å; I53-G210 WeakPolarHBondContact O-CA 3.22Å
54C98.3Very high94.8Very high6 Ų630.7 Ų30.74%0.04117%0.172CC..EExtended strand (participates in β ladder)trans-131.5173.5161.9-84.50000108.3L46 L48 C70 G210 S212L46-C54 WeakPolarHBondContact CA-O 3.49Å; L46-C54 HydrophobicContact CB-CB 3.98Å; L46-C54 WeakPolarHBondContact CB-O 3.49Å; L46-C54 HydrophobicContact CD1-CB 3.92Å; L46-C54 HydrophobicContact CG-CB 4.41Å; L46-C54 PolarHBondContact N-O 2.83Å; L46-C54 PolarHBondContact O-N 3.42Å; L48-C54 HydrophobicContact CD1-CB 4.14Å; C54-C70 HydrophobicContact CB-CB 3.77Å; C54-C70 WeakPolarHBondContact CB-SG 3.15Å; C54-C70 WeakPolarHBondContact SG-CB 3.34Å; C54-C70 CovalentContact SG-SG 2.04Å; C54-C70 PolarHBondContact SG-SG 3.25Å; C54-G210 CarbonylContact C-O 3.59Å; C54-G210 WeakPolarHBondContact CA-O 3.46Å; C54-S212 WeakPolarHBondContact CB-O 3.17Å
55A98.6Very high94.8Very high0 Ų030.7 Ų30.70%017%0.172CC..EExtended strand (participates in β ladder)trans-111.6175.2170.300000111.4M43 V44 T66 S212 G213M43-A55 HydrophobicContact CE-CB 4.15Å; V44-A55 CarbonylContact O-C 3.35Å; V44-A55 VanDerWaalsContact O-CA 3.26Å; V44-A55 WeakPolarHBondContact O-CA 3.33Å; A55-T66 PolarHBondContact O-OG1 3.08Å; A55-S212 PolarHBondContact N-O 2.79Å; A55-G213 CarbonylContact O-C 3.16Å; A55-G213 WeakPolarHBondContact O-CA 3.43Å
56G98.8Very high94.8Very high0 Ų030.7 Ų30.70%017%0.172CC..EExtended strand (participates in β ladder)trans-165.4176.2174.500000111.6V44 L65 G213V44-G56 WeakPolarHBondContact CB-O 3.36Å; V44-G56 PolarHBondContact N-O 3.34Å; V44-G56 PolarHBondContact O-N 2.93Å; G56-L65 CarbonylContact C-O 3.44Å; G56-L65 WeakPolarHBondContact CA-O 3.26Å; G56-G213 WeakPolarHBondContact CA-O 3.31Å
57A98.9Very high94.8Very high0 Ų030.6 Ų30.60%017%0.172CC..EExtended strand (participates in β ladder)trans-120.8132.4171.500000110.5I59 V64 L65 L133 P215 F222A57-I59 HydrophobicContact CB-CG2 4.23Å; A57-I59 PolarHBondContact O-N 3.32Å; A57-V64 CarbonylContact O-C 3.5Å; A57-V64 WeakPolarHBondContact O-CA 3.2Å; A57-L65 PolarHBondContact N-O 2.96Å; A57-L65 PolarHBondContact O-N 2.57Å; A57-L133 HydrophobicContact CB-CB 4.48Å; A57-L133 HydrophobicContact CB-CD2 3.91Å; A57-P215 HydrophobicContact CB-CB 4.11Å; A57-P215 HydrophobicContact CB-CG 4.06Å; A57-F222 HydrophobicContact CB-CE1 3.77Å; A57-F222 HydrophobicContact CB-CZ 3.85Å
58L98.9Very high95Very high1 Ų129 Ų291%0.00516%0.162CC..EExtended strand (participates in β ladder)trans-74.7112.1169.3-171.272000108.4Y42 V44 A60 V64 L80 L120 A124 I126 V130 I132 L133Y42-L58 PolarHBondContact O-N 3.2Å; V44-L58 HydrophobicContact CG2-CB 4.05Å; L58-A60 WeakPolarHBondContact CD1-O 3.22Å; L58-A60 WeakPolarHBondContact CG-O 3.39Å; L58-V64 HydrophobicContact CD1-CG2 3.95Å; L58-L80 HydrophobicContact CD1-CD1 4.24Å; L58-L80 HydrophobicContact CD1-CD2 4.14Å; L58-L80 HydrophobicContact CD2-CD1 4.27Å; L58-L120 HydrophobicContact CD1-CD1 4.38Å; L58-A124 HydrophobicContact CD2-CB 4.11Å; L58-I126 HydrophobicContact CD2-CD1 4.04Å; L58-V130 HydrophobicContact CD2-CG1 3.76Å; L58-I132 HydrophobicContact CD2-CG1 4.46Å; L58-I132 CarbonylContact O-C 3.51Å; L58-I132 WeakPolarHBondContact O-CA 3.04Å; L58-L133 PolarHBondContact O-N 3.11Å
59I98.9Very high95.2Very high15 Ų1530.8 Ų30.88%0.07717%0.169CC..EExtended strand (participates in β ladder)trans-109.4-11.4-175.161.6159.1000113.4A57 W63 L65 L117 I132 L135 F222 I254 I258A57-I59 HydrophobicContact CB-CG2 4.23Å; A57-I59 PolarHBondContact O-N 3.32Å; I59-W63 HydrophobicContact CG1-CB 3.98Å; I59-W63 WeakPolarHBondContact CG1-O 3.35Å; I59-W63 PolarHBondContact N-O 2.97Å; I59-L65 HydrophobicContact CD1-CB 4.08Å; I59-L65 HydrophobicContact CG1-CB 4.34Å; I59-L65 HydrophobicContact CG2-CB 3.99Å; I59-L117 HydrophobicContact CD1-CD2 3.53Å; I59-L117 HydrophobicContact CG1-CD2 4.48Å; I59-I132 VanDerWaalsContact O-CG2 3.26Å; I59-I132 WeakPolarHBondContact O-CG2 3.32Å; I59-L135 HydrophobicContact CD1-CD2 4.49Å; I59-L135 HydrophobicContact CG2-CD2 4.28Å; I59-F222 HydrophobicContact CG2-CE1 3.9Å; I59-I254 HydrophobicContact CD1-CG2 3.75Å; I59-I258 HydrophobicContact CD1-CD1 3.82Å
60A98.6Very high95.8Very high23 Ų2325.9 Ų25.919%0.1915%0.147CC..EExtended strand (participates in β ladder)trans-153.7172.1162.600000108.6L58 D62 W63L58-A60 WeakPolarHBondContact CD1-O 3.22Å; L58-A60 WeakPolarHBondContact CG-O 3.39Å; A60-D62 PolarHBondContact O-N 2.67Å; A60-D62 VanDerWaalsContact O-N 3.09Å; A60-W63 HydrophobicContact CB-CB 3.93Å; A60-W63 HydrophobicContact CB-CG 4.29Å; A60-W63 PolarHBondContact N-O 2.63Å; A60-W63 PolarHBondContact O-N 2.9Å; A60-W63 VanDerWaalsContact O-N 3.13Å
61E98.6Very high96.7Very high72 Ų7229.1 Ų29.134%0.33615%0.15SC..THydrogen-bonded Turntrans-54.9-33.4-175.7-61.1179.7154.400113.2K123 A124 I126 I132E61-K123 HydrophobicContact CB-CB 4.01Å; E61-K123 HydrophobicContact CB-CD 4.44Å; E61-K123 HydrophobicContact CB-CG 4.01Å; E61-K123 VanDerWaalsContact OE2-CD 3.3Å; E61-K123 WeakPolarHBondContact OE2-CD 3.46Å; E61-K123 WeakPolarHBondContact OE2-CE 3.32Å; E61-K123 IonicContact OE2-NZ 2.74Å; E61-K123 PolarHBondContact OE2-NZ 3.13Å; E61-A124 VanDerWaalsContact O-CB 3.22Å; E61-A124 WeakPolarHBondContact O-CB 3.44Å; E61-A124 PolarHBondContact O-N 2.78Å; E61-I126 HydrophobicContact CG-CD1 4.32Å; E61-I126 HydrophobicContact CG-CG1 4.01Å; E61-I132 HydrophobicContact CG-CD1 4.07Å
62D98.6Very high97.6Very high35 Ų3521.8 Ų21.819%0.18712%0.12CC..THydrogen-bonded Turntrans-119.517.9179.963.6-41.2000113.2A60 Q119 L120 K123A60-D62 PolarHBondContact O-N 2.67Å; A60-D62 VanDerWaalsContact O-N 3.09Å; D62-Q119 CarbonylContact O-C 3.56Å; D62-Q119 WeakPolarHBondContact O-CA 3.08Å; D62-L120 HydrophobicContact CB-CB 4.37Å; D62-L120 PolarHBondContact O-N 2.98Å; D62-K123 HydrophobicContact CB-CG 4.07Å
63W98.9Very high97.8Very high2 Ų220.8 Ų20.81%0.00811%0.111CC..EExtended strand (participates in β ladder)trans-130.9124.9-178.1-68.486.9000113.3I59 A60 F101 L117 L118 Q119 T257 I258 A261I59-W63 HydrophobicContact CG1-CB 3.98Å; I59-W63 WeakPolarHBondContact CG1-O 3.35Å; I59-W63 PolarHBondContact N-O 2.97Å; A60-W63 HydrophobicContact CB-CB 3.93Å; A60-W63 HydrophobicContact CB-CG 4.29Å; A60-W63 PolarHBondContact N-O 2.63Å; A60-W63 PolarHBondContact O-N 2.9Å; A60-W63 VanDerWaalsContact O-N 3.13Å; W63-F101 AromaticContact CH2-CD2 3.93Å; W63-F101 HydrophobicContact CH2-CD2 3.93Å; W63-F101 AromaticContact CH2-CE2 3.58Å; W63-F101 HydrophobicContact CH2-CE2 3.58Å; W63-F101 HydrophobicContact CH2-CZ 4.08Å; W63-F101 AromaticContact CZ3-CD2 3.73Å; W63-F101 HydrophobicContact CZ3-CD2 3.73Å; W63-F101 AromaticContact CZ3-CE2 3.85Å; W63-F101 HydrophobicContact CZ3-CE2 3.85Å; W63-F101 HydrophobicContact CZ3-CG 4.49Å; W63-L117 HydrophobicContact CE3-CB 3.98Å; W63-L117 HydrophobicContact CE3-CD1 4.36Å; W63-L117 HydrophobicContact CE3-CD2 4.32Å; W63-L117 HydrophobicContact CE3-CG 4.47Å; W63-L117 HydrophobicContact CZ3-CB 3.91Å; W63-L117 HydrophobicContact CZ3-CD1 4.28Å; W63-L118 WeakPolarHBondContact CA-O 3.17Å; W63-Q119 HydrophobicContact CD2-CB 4.49Å; W63-Q119 HydrophobicContact CE3-CB 4.22Å; W63-Q119 HydrophobicContact CH2-CB 3.79Å; W63-Q119 HydrophobicContact CH2-CG 4.1Å; W63-Q119 HydrophobicContact CZ2-CB 4.02Å; W63-Q119 HydrophobicContact CZ2-CG 3.82Å; W63-Q119 HydrophobicContact CZ3-CB 3.89Å; W63-T257 HydrophobicContact CH2-CG2 4.2Å; W63-T257 HydrophobicContact CZ3-CG2 4.16Å; W63-I258 HydrophobicContact CD2-CG1 3.77Å; W63-I258 HydrophobicContact CE3-CG1 4.08Å; W63-I258 HydrophobicContact CG-CD1 4.36Å; W63-I258 HydrophobicContact CG-CG1 4.02Å; W63-A261 HydrophobicContact CH2-CB 3.64Å; W63-A261 HydrophobicContact CZ2-CB 3.59Å
64V98.9Very high97.5Very high0 Ų030.9 Ų30.90%016%0.155CC..EExtended strand (participates in β ladder)trans-111.9134.7171.8176.10000109.8V44 A57 L58 V78 L117 L118 L120V44-V64 HydrophobicContact CB-CG1 4.15Å; V44-V64 HydrophobicContact CG1-CG1 3.99Å; V44-V64 HydrophobicContact CG1-CG2 4.22Å; V44-V64 HydrophobicContact CG2-CG1 4.02Å; V44-V64 HydrophobicContact CG2-CG2 4.06Å; A57-V64 CarbonylContact O-C 3.5Å; A57-V64 WeakPolarHBondContact O-CA 3.2Å; L58-V64 HydrophobicContact CD1-CG2 3.95Å; V64-V78 HydrophobicContact CG2-CG1 3.99Å; V64-L117 CarbonylContact O-C 3.56Å; V64-L117 WeakPolarHBondContact O-CA 3.33Å; V64-L118 HydrophobicContact CB-CB 4.23Å; V64-L118 HydrophobicContact CB-CD1 4.46Å; V64-L118 HydrophobicContact CG1-CD1 4.37Å; V64-L118 PolarHBondContact N-O 2.86Å; V64-L118 PolarHBondContact O-N 2.78Å; V64-L120 HydrophobicContact CG2-CD1 4.24Å; V64-L120 HydrophobicContact CG2-CD2 4.16Å; V64-L120 HydrophobicContact CG2-CG 4.46Å
65L98.9Very high97.1Very high0 Ų038.9 Ų38.90%018%0.184CC..EExtended strand (participates in β ladder)trans-99.6131.4167.8-175.963.8000109.6G56 A57 I59 L115 L117 F222 V225 L246 W253 I254G56-L65 CarbonylContact C-O 3.44Å; G56-L65 WeakPolarHBondContact CA-O 3.26Å; A57-L65 PolarHBondContact N-O 2.96Å; A57-L65 PolarHBondContact O-N 2.57Å; I59-L65 HydrophobicContact CD1-CB 4.08Å; I59-L65 HydrophobicContact CG1-CB 4.34Å; I59-L65 HydrophobicContact CG2-CB 3.99Å; L65-L115 HydrophobicContact CD1-CD2 4.31Å; L65-L117 HydrophobicContact CB-CD2 4.17Å; L65-L117 HydrophobicContact CD1-CD2 3.78Å; L65-L117 HydrophobicContact CD1-CG 4.2Å; L65-F222 HydrophobicContact CD2-CE1 4.04Å; L65-F222 HydrophobicContact CD2-CZ 3.86Å; L65-V225 HydrophobicContact CD2-CG2 3.89Å; L65-V225 HydrophobicContact CG-CG2 4.16Å; L65-L246 HydrophobicContact CD2-CD2 4.02Å; L65-W253 HydrophobicContact CD1-CZ3 4.43Å; L65-I254 HydrophobicContact CD1-CD1 4.23Å; L65-I254 HydrophobicContact CD1-CG1 4.42Å; L65-I254 HydrophobicContact CD2-CD1 3.86Å
66T98.9Very high97Very high0 Ų039.5 Ų39.50%019%0.189CC..EExtended strand (participates in β ladder)trans-147.9-173.5179.1-172.30000110L46 A55 K116 L118L46-T66 HydrophobicContact CD1-CG2 3.94Å; L46-T66 VanDerWaalsContact CD1-OG1 3.28Å; L46-T66 WeakPolarHBondContact CD1-OG1 3.17Å; A55-T66 PolarHBondContact O-OG1 3.08Å; T66-K116 HydrophobicContact CG2-CB 4.25Å; T66-K116 PolarHBondContact N-O 2.94Å; T66-K116 PolarHBondContact O-N 2.78Å; T66-L118 HydrophobicContact CG2-CD1 3.97Å; T66-L118 HydrophobicContact CG2-CD2 4.45Å; T66-L118 HydrophobicContact CG2-CG 4.02Å
67A98.8Very high96.8Very high0 Ų043.3 Ų43.30%021%0.207CC..  trans-82.9148.4175.400000111.6C70A67-C70 WeakPolarHBondContact O-CB 3.02Å; A67-C70 PolarHBondContact O-N 2.85Å
68A98.6Very high96.8Very high8 Ų843.3 Ų43.37%0.06621%0.207CC..THydrogen-bonded Turntrans-67.7-36.9179.500000112.4C70 Y106 D114 K116A68-C70 PolarHBondContact O-N 3.05Å; A68-Y106 HydrophobicContact CB-CD1 3.5Å; A68-Y106 VanDerWaalsContact CB-CD1 3.5Å; A68-Y106 HydrophobicContact CB-CD2 4.15Å; A68-Y106 HydrophobicContact CB-CE1 3.79Å; A68-Y106 HydrophobicContact CB-CE2 4.4Å; A68-Y106 HydrophobicContact CB-CG 3.69Å; A68-D114 WeakPolarHBondContact CA-OD1 3.24Å; A68-D114 WeakPolarHBondContact CB-OD1 3.38Å; A68-D114 PolarHBondContact N-OD1 3.43Å; A68-K116 HydrophobicContact CB-CB 4.32Å; A68-K116 PolarHBondContact O-NZ 2.84Å
69H97.5Very high96.8Very high51 Ų5144 Ų4424%0.23621%0.21CC..THydrogen-bonded Turntrans-69.4-11.2179.876.6-97.3000114.4N71 D114 S212 S227H69-N71 PolarHBondContact O-N 3.17Å; H69-N71 PolarHBondContact O-ND2 3.33Å; H69-D114 IonicContact CE1-OD2 3.98Å; H69-D114 PolarHBondContact CE1-OD2 3.02Å; H69-D114 IonicContact CG-OD1 3.77Å; H69-D114 IonicContact CG-OD2 3.8Å; H69-D114 PolarHBondContact N-OD1 3.44Å; H69-D114 VanDerWaalsContact ND1-CG 3.33Å; H69-D114 IonicContact ND1-OD1 3.72Å; H69-D114 PolarHBondContact ND1-OD1 3.5Å; H69-D114 IonicContact ND1-OD2 2.77Å; H69-D114 PolarHBondContact ND1-OD2 2.64Å; H69-S212 VanDerWaalsContact CE1-CB 3.47Å; H69-S212 WeakPolarHBondContact CE1-CB 3.29Å; H69-S212 PolarHBondContact CE1-OG 2.89Å; H69-S212 WeakPolarHBondContact NE2-CB 3.49Å; H69-S212 PolarHBondContact NE2-OG 3.42Å; H69-S227 PolarHBondContact CE1-O 3.2Å
70C97.3Very high96.8Very high2 Ų243.3 Ų43.31%0.01421%0.207CC..  trans-7196.7172.8-69.20000109.5L48 C54 A67 A68 L72 K116L48-C70 HydrophobicContact CD1-CB 4.4Å; C54-C70 HydrophobicContact CB-CB 3.77Å; C54-C70 WeakPolarHBondContact CB-SG 3.15Å; C54-C70 WeakPolarHBondContact SG-CB 3.34Å; C54-C70 CovalentContact SG-SG 2.04Å; C54-C70 PolarHBondContact SG-SG 3.25Å; A67-C70 WeakPolarHBondContact O-CB 3.02Å; A67-C70 PolarHBondContact O-N 2.85Å; A68-C70 PolarHBondContact O-N 3.05Å; C70-L72 WeakPolarHBondContact O-CD1 3.45Å; C70-L72 PolarHBondContact O-N 2.9Å; C70-K116 WeakPolarHBondContact O-CE 3.23Å; C70-K116 PolarHBondContact O-NZ 2.99Å
71N95.1Very high96.8Very high127 Ų12742.5 Ų42.568%0.67920%0.2SC*.  trans-81.5118.1-174.8-63.3-56.5000111.5H69H69-N71 PolarHBondContact O-N 3.17Å; H69-N71 PolarHBondContact O-ND2 3.33Å
72L94.8Very high96.8Very high28 Ų2839.3 Ų39.315%0.14719%0.186CC..  trans-94151175.2-72.875.8000110.3L48 C70 V97 L118L48-L72 HydrophobicContact CD2-CD1 4.07Å; L48-L72 HydrophobicContact CD2-CG 3.77Å; C70-L72 WeakPolarHBondContact O-CD1 3.45Å; C70-L72 PolarHBondContact O-N 2.9Å; L72-V97 HydrophobicContact CD2-CB 4.39Å; L72-V97 HydrophobicContact CD2-CG2 3.56Å; L72-L118 HydrophobicContact CD1-CD2 4.3Å; L72-L118 HydrophobicContact CD2-CD1 3.98Å; L72-L118 HydrophobicContact CD2-CD2 4.1Å
73D92.3Very high96.8Very high57 Ų5738 Ų3831%0.30518%0.179SC..  trans-126.2180169.979.8-12.4000110.5H49 R75 S76H49-D73 WeakPolarHBondContact CB-OD2 3.44Å; H49-D73 IonicContact CD2-OD2 3.4Å; H49-D73 IonicContact CG-OD2 3.95Å; D73-R75 PolarHBondContact O-N 3.44Å; D73-R75 WeakPolarHBondContact OD1-CA 3.48Å; D73-R75 PolarHBondContact OD1-N 2.75Å; D73-R75 IonicContact OD2-NE 2.9Å; D73-R75 IonicContact OD2-NH2 3.92Å; D73-S76 PolarHBondContact N-OG 3.13Å; D73-S76 VanDerWaalsContact O-CB 3.31Å; D73-S76 WeakPolarHBondContact O-CB 3.13Å; D73-S76 PolarHBondContact O-N 2.87Å; D73-S76 PolarHBondContact O-OG 2.83Å; D73-S76 PolarHBondContact OD1-N 3.27Å; D73-S76 PolarHBondContact OD1-OG 3.39Å
74K88.8Confident96.8Very high221 Ų22137.9 Ų37.996%0.96118%0.179SC*.THydrogen-bonded Turntrans-61.9-16.2180-64.6-175.2-179.8-179.90114.4
75R90.4Very high96.6Very high174 Ų17440.1 Ų40.166%0.65719%0.19SC*.THydrogen-bonded Turntrans-99.4-7.3179.7-68.9-179.5-71-169.7-6.9112.4H49 D73H49-R75 PolarHBondContact CD2-NH2 3.15Å; H49-R75 PolarHBondContact NE2-NH2 3.31Å; D73-R75 PolarHBondContact O-N 3.44Å; D73-R75 WeakPolarHBondContact OD1-CA 3.48Å; D73-R75 PolarHBondContact OD1-N 2.75Å; D73-R75 IonicContact OD2-NE 2.9Å; D73-R75 IonicContact OD2-NH2 3.92Å
76S95.4Very high96.4Very high14 Ų1445.4 Ų45.410%0.09822%0.222CC..  trans-67.5143.2-178.3-60.80000110.9S47 D73S47-S76 CarbonylContact O-C 3.25Å; S47-S76 VanDerWaalsContact O-CA 3.23Å; S47-S76 WeakPolarHBondContact O-CA 3.3Å; D73-S76 PolarHBondContact N-OG 3.13Å; D73-S76 VanDerWaalsContact O-CB 3.31Å; D73-S76 WeakPolarHBondContact O-CB 3.13Å; D73-S76 PolarHBondContact O-N 2.87Å; D73-S76 PolarHBondContact O-OG 2.83Å; D73-S76 PolarHBondContact OD1-N 3.27Å; D73-S76 PolarHBondContact OD1-OG 3.39Å
77Q96.6Very high96.3Very high80 Ų8053.7 Ų53.737%0.37425%0.254SS..EExtended strand (participates in β ladder)trans-122.8140.7-178-64.9-177.7-20.800110.4S47 I79 I94S47-Q77 PolarHBondContact N-O 2.93Å; S47-Q77 PolarHBondContact O-N 2.85Å; Q77-I79 HydrophobicContact CB-CD1 4.44Å; Q77-I79 HydrophobicContact CB-CG1 4.11Å; Q77-I94 HydrophobicContact CB-CG2 4.2Å; Q77-I94 HydrophobicContact CG-CG2 4.15Å
78V98.5Very high96.2Very high0 Ų063.8 Ų63.80%030%0.298CS..EExtended strand (participates in β ladder)trans-100.3113.6169.4176.10000107.1V44 L46 V64 L80 M95 V97 L118 L120V44-V78 HydrophobicContact CG1-CG1 3.52Å; L46-V78 HydrophobicContact CD2-CB 4.33Å; L46-V78 HydrophobicContact CD2-CG1 4.31Å; L46-V78 HydrophobicContact CD2-CG2 3.78Å; V64-V78 HydrophobicContact CG2-CG1 3.99Å; V78-L80 HydrophobicContact CG1-CD2 4.22Å; V78-M95 HydrophobicContact CB-CB 4.09Å; V78-M95 HydrophobicContact CG1-CB 4.34Å; V78-M95 PolarHBondContact N-O 3.05Å; V78-M95 PolarHBondContact O-N 2.88Å; V78-V97 HydrophobicContact CG2-CG2 3.54Å; V78-L118 HydrophobicContact CG2-CD1 4.27Å; V78-L120 HydrophobicContact CB-CD2 4.17Å; V78-L120 HydrophobicContact CG1-CD2 3.92Å; V78-L120 HydrophobicContact CG2-CD2 4.01Å
79I98.7Very high96.2Very high14 Ų1465 Ų657%0.07230%0.302CS..EExtended strand (participates in β ladder)trans-113.6114.2-173.8-50.8172.9000108.7L45 Q77 A82 K92L45-I79 HydrophobicContact CB-CB 4.21Å; L45-I79 HydrophobicContact CD2-CD1 4.06Å; L45-I79 HydrophobicContact CG-CD1 4.45Å; L45-I79 PolarHBondContact N-O 2.93Å; L45-I79 PolarHBondContact O-N 3Å; Q77-I79 HydrophobicContact CB-CD1 4.44Å; Q77-I79 HydrophobicContact CB-CG1 4.11Å; I79-A82 HydrophobicContact CG2-CB 4Å; I79-K92 HydrophobicContact CG2-CB 4.39Å; I79-K92 HydrophobicContact CG2-CD 4.08Å; I79-K92 HydrophobicContact CG2-CG 3.96Å
80L98.9Very high96.2Very high2 Ų271.6 Ų71.61%0.0133%0.333CS..EExtended strand (participates in β ladder)trans-97.7154.8176.7-48174.8000110.1V44 L58 V78 A82 K92 Q93 M95 A124 V130V44-L80 HydrophobicContact CB-CD2 4.21Å; V44-L80 HydrophobicContact CG1-CD2 3.93Å; V44-L80 HydrophobicContact CG2-CD2 3.54Å; L58-L80 HydrophobicContact CD1-CD1 4.24Å; L58-L80 HydrophobicContact CD1-CD2 4.14Å; L58-L80 HydrophobicContact CD2-CD1 4.27Å; V78-L80 HydrophobicContact CG1-CD2 4.22Å; L80-A82 PolarHBondContact O-N 3.47Å; L80-K92 VanDerWaalsContact O-CA 3.3Å; L80-K92 WeakPolarHBondContact O-CA 3.35Å; L80-Q93 HydrophobicContact CB-CB 4.23Å; L80-Q93 PolarHBondContact N-O 2.76Å; L80-Q93 PolarHBondContact O-N 3Å; L80-M95 HydrophobicContact CD1-CG 3.89Å; L80-M95 HydrophobicContact CG-CG 4.2Å; L80-A124 HydrophobicContact CD1-CB 3.4Å; L80-V130 HydrophobicContact CB-CG1 4.04Å; L80-V130 HydrophobicContact CB-CG2 4.02Å; L80-V130 HydrophobicContact CD1-CG1 4.03Å
81G98.6Very high96.2Very high5 Ų573.9 Ų73.95%0.05234%0.343CS..SBendtrans68.412.7173.900000114.7H38 Y129H38-G81 PolarHBondContact CE1-O 3.09Å; H38-G81 PolarHBondContact ND1-O 2.8Å; G81-Y129 WeakPolarHBondContact CA-O 3.32Å
82A98.6Very high96.4Very high6 Ų669.8 Ų69.85%0.0532%0.319CS..  trans-75.7144.5177.100000111.8I79 L80 E89 K92 W153I79-A82 HydrophobicContact CG2-CB 4Å; L80-A82 PolarHBondContact O-N 3.47Å; A82-E89 WeakPolarHBondContact CA-OE2 3.35Å; A82-K92 HydrophobicContact CB-CD 4.39Å; A82-K92 HydrophobicContact CB-CG 4.05Å; A82-W153 HydrophobicContact CB-CZ2 4.16Å; A82-W153 WeakPolarHBondContact O-CZ2 3.44Å
83H98.5Very high96.6Very high6 Ų669.8 Ų69.83%0.02832%0.319CS..SBendtrans-110.8-53.6158.4179.662.6000110.7E34 V35 P37 E89 W153 T165 L166E34-H83 IonicContact OE1-CD2 2.79Å; E34-H83 IonicContact OE1-CE1 3.26Å; E34-H83 IonicContact OE1-NE2 3.52Å; E34-H83 PolarHBondContact OE1-NE2 2.93Å; V35-H83 PolarHBondContact O-CE1 2.95Å; P37-H83 HydrophobicContact CB-CB 4.13Å; H83-E89 WeakPolarHBondContact CB-OE1 3.23Å; H83-E89 PolarHBondContact N-OE2 2.97Å; H83-W153 PolarHBondContact O-NE1 2.87Å; H83-T165 CarbonylContact O-C 3.5Å; H83-T165 WeakPolarHBondContact O-CA 3.44Å; H83-L166 PolarHBondContact O-N 2.86Å
84S97.8Very high96.9Very high1 Ų172 Ų721%0.00733%0.33CS..BIsolated β-bridgetrans-93.4143.2173.81650000111.3T86 R87 E89 K92 D164S84-T86 PolarHBondContact OG-N 2.83Å; S84-R87 WeakPolarHBondContact OG-CB 3.33Å; S84-R87 VanDerWaalsContact OG-CG 3.32Å; S84-R87 WeakPolarHBondContact OG-CG 3.38Å; S84-R87 PolarHBondContact OG-N 2.76Å; S84-E89 WeakPolarHBondContact CB-OE1 3.13Å; S84-E89 PolarHBondContact N-OE1 2.61Å; S84-K92 WeakPolarHBondContact O-CE 3.08Å; S84-K92 PolarHBondContact O-NZ 3.03Å; S84-D164 CarbonylContact C-O 3.41Å; S84-D164 WeakPolarHBondContact CA-O 3.37Å; S84-D164 WeakPolarHBondContact CB-OD2 3.49Å; S84-D164 VanDerWaalsContact OG-CG 3.31Å; S84-D164 PolarHBondContact OG-OD1 3.06Å; S84-D164 PolarHBondContact OG-OD2 3.44Å
85I95.1Very high97.3Very high47 Ų4762.3 Ų62.324%0.24129%0.288CS..SBendtrans-67.5-52.2171.6-62176.9000109.3L45 I53 K92 W153 S163 D164L45-I85 HydrophobicContact CD1-CG1 4.49Å; L45-I85 HydrophobicContact CD2-CB 4.39Å; L45-I85 HydrophobicContact CD2-CG1 3.91Å; L45-I85 HydrophobicContact CD2-CG2 4.36Å; I53-I85 HydrophobicContact CD1-CD1 3.95Å; I85-K92 PolarHBondContact O-NZ 2.68Å; I85-W153 HydrophobicContact CD1-CB 4.01Å; I85-W153 HydrophobicContact CD1-CG 4.28Å; I85-W153 HydrophobicContact CG1-CB 4.39Å; I85-W153 HydrophobicContact CG1-CG 4.12Å; I85-S163 VanDerWaalsContact CD1-O 3.28Å; I85-S163 WeakPolarHBondContact CD1-O 3.26Å; I85-D164 PolarHBondContact N-O 3.38Å; I85-D164 PolarHBondContact N-OD1 2.69Å
86T94.6Very high97.7Very high110 Ų11062.9 Ų62.968%0.67529%0.29SS*.SBendtrans-86.9-30.8-167.358.60000114.3S84 D164S84-T86 PolarHBondContact OG-N 2.83Å; T86-D164 VanDerWaalsContact CB-OD1 3.28Å; T86-D164 WeakPolarHBondContact CB-OD1 2.88Å; T86-D164 VanDerWaalsContact CG2-OD1 3.23Å; T86-D164 WeakPolarHBondContact CG2-OD1 2.83Å; T86-D164 PolarHBondContact N-OD1 3.14Å; T86-D164 PolarHBondContact OG1-OD1 2.87Å
87R96.6Very high97.8Very high174 Ų17464 Ų6466%0.65730%0.296SS*.SBendtrans-71145.9-178.4-64.9177.664.4-175.4-2.1111.1S84 K92S84-R87 WeakPolarHBondContact OG-CB 3.33Å; S84-R87 VanDerWaalsContact OG-CG 3.32Å; S84-R87 WeakPolarHBondContact OG-CG 3.38Å; S84-R87 PolarHBondContact OG-N 2.76Å; R87-K92 PolarHBondContact O-NZ 3.46Å
88K96.9Very high97.8Very high212 Ų21266.8 Ų66.892%0.92231%0.307SS*.  trans-78.1122.3167.8-64.8-176.7-178.31790108.2
89E98.3Very high97.8Very high33 Ų3372.2 Ų72.215%0.15433%0.331CS..  trans-124.8136-179.5-66.2171.7163.500107.1H38 A82 H83 S84 E91 K92H38-E89 IonicContact CE1-OE2 3.76Å; A82-E89 WeakPolarHBondContact CA-OE2 3.35Å; H83-E89 WeakPolarHBondContact CB-OE1 3.23Å; H83-E89 PolarHBondContact N-OE2 2.97Å; S84-E89 WeakPolarHBondContact CB-OE1 3.13Å; S84-E89 PolarHBondContact N-OE1 2.61Å; E89-E91 PolarHBondContact O-N 2.89Å; E89-K92 HydrophobicContact CB-CD 4.16Å; E89-K92 HydrophobicContact CB-CG 4.03Å; E89-K92 PolarHBondContact O-N 3.1Å; E89-K92 WeakPolarHBondContact OE2-CE 3.35Å
90Q98.1Very high97.7Very high190 Ų19075.1 Ų75.189%0.88834%0.344SS*.THydrogen-bonded Turntrans-72.2-21-178.6-67.6-175.3-24.100111.6K92Q90-K92 VanDerWaalsContact C-N 3.31Å
91E98.4Very high97.7Very high51 Ų5176.8 Ų76.824%0.23835%0.351CS..THydrogen-bonded Turntrans-74.1-21.8-179.9-62.973.6-161.600112.5E89 Q93 Y129E89-E91 PolarHBondContact O-N 2.89Å; E91-Q93 PolarHBondContact O-N 3.11Å; E91-Y129 HydrophobicContact CB-CD2 4.04Å; E91-Y129 HydrophobicContact CB-CG 4.13Å; E91-Y129 HydrophobicContact CG-CD1 4.23Å; E91-Y129 HydrophobicContact CG-CD2 3.35Å; E91-Y129 HydrophobicContact CG-CE1 4.49Å; E91-Y129 HydrophobicContact CG-CE2 3.66Å; E91-Y129 HydrophobicContact CG-CG 3.64Å
92K98.7Very high97.7Very high40 Ų4079.9 Ų79.917%0.17437%0.37CS..  trans-65.2131.6-177.5-82.8177179.2178.20111.8I79 L80 A82 S84 I85 R87 E89 Q90I79-K92 HydrophobicContact CG2-CB 4.39Å; I79-K92 HydrophobicContact CG2-CD 4.08Å; I79-K92 HydrophobicContact CG2-CG 3.96Å; L80-K92 VanDerWaalsContact O-CA 3.3Å; L80-K92 WeakPolarHBondContact O-CA 3.35Å; A82-K92 HydrophobicContact CB-CD 4.39Å; A82-K92 HydrophobicContact CB-CG 4.05Å; S84-K92 WeakPolarHBondContact O-CE 3.08Å; S84-K92 PolarHBondContact O-NZ 3.03Å; I85-K92 PolarHBondContact O-NZ 2.68Å; R87-K92 PolarHBondContact O-NZ 3.46Å; E89-K92 HydrophobicContact CB-CD 4.16Å; E89-K92 HydrophobicContact CB-CG 4.03Å; E89-K92 PolarHBondContact O-N 3.1Å; E89-K92 WeakPolarHBondContact OE2-CE 3.35Å; Q90-K92 VanDerWaalsContact C-N 3.31Å
93Q98.7Very high97.7Very high29 Ų2980.7 Ų80.714%0.13637%0.372CS..EExtended strand (participates in β ladder)trans-115.4112.4167-56.317935.500108.5L80 E91 M95 K125 N127 V130L80-Q93 HydrophobicContact CB-CB 4.23Å; L80-Q93 PolarHBondContact N-O 2.76Å; L80-Q93 PolarHBondContact O-N 3Å; E91-Q93 PolarHBondContact O-N 3.11Å; Q93-M95 HydrophobicContact CB-SD 4.28Å; Q93-K125 PolarHBondContact NE2-O 2.89Å; Q93-N127 PolarHBondContact NE2-ND2 2.75Å; Q93-V130 HydrophobicContact CG-CG2 4.49Å
94I98.3Very high97.7Very high104 Ų10485.3 Ų85.353%0.53340%0.403SS..EExtended strand (participates in β ladder)trans-92.1111.5179.3-56.1176.3000108.2Q77Q77-I94 HydrophobicContact CB-CG2 4.2Å; Q77-I94 HydrophobicContact CG-CG2 4.15Å
95M98.3Very high97.7Very high16 Ų1689.4 Ų89.48%0.07943%0.43CS..EExtended strand (participates in β ladder)trans-110.9155.9-174.3-50.3-65.6-75.700110.3V78 L80 Q93 L120 E122V78-M95 HydrophobicContact CB-CB 4.09Å; V78-M95 HydrophobicContact CG1-CB 4.34Å; V78-M95 PolarHBondContact N-O 3.05Å; V78-M95 PolarHBondContact O-N 2.88Å; L80-M95 HydrophobicContact CD1-CG 3.89Å; L80-M95 HydrophobicContact CG-CG 4.2Å; Q93-M95 HydrophobicContact CB-SD 4.28Å; M95-L120 HydrophobicContact CB-CD1 4.18Å; M95-L120 HydrophobicContact CB-CD2 4.4Å; M95-L120 HydrophobicContact CE-CB 4.48Å; M95-L120 HydrophobicContact CE-CD1 4.09Å; M95-L120 HydrophobicContact CG-CD1 4.22Å; M95-E122 HydrophobicContact CE-CB 4.15Å; M95-E122 WeakPolarHBondContact CE-O 3.46Å
96R97.4Very high97.9Very high187 Ų18789.8 Ų89.871%0.70643%0.429SS*.  trans-109.6151.8172.1-66.2-174.2177.4109.6-1.4110.4L120 T121R96-L120 WeakPolarHBondContact O-CA 3.4Å; R96-T121 HydrophobicContact CB-CG2 3.93Å; R96-T121 PolarHBondContact O-N 3.23Å; R96-T121 PolarHBondContact O-OG1 3.48Å
97V97.9Very high98Very high38 Ų3887.6 Ų87.623%0.2341%0.413CS..EExtended strand (participates in β ladder)trans-84125.5173.4179.40000109.3L72 V78 E100 L118L72-V97 HydrophobicContact CD2-CB 4.39Å; L72-V97 HydrophobicContact CD2-CG2 3.56Å; V78-V97 HydrophobicContact CG2-CG2 3.54Å; V97-E100 HydrophobicContact CG1-CG 3.91Å; V97-L118 HydrophobicContact CG1-CB 4.3Å; V97-L118 HydrophobicContact CG1-CD2 4.35Å; V97-L118 HydrophobicContact CG2-CB 4.16Å; V97-L118 HydrophobicContact CG2-CD1 4.17Å; V97-L118 HydrophobicContact CG2-CD2 4.48Å
98K96.9Very high98Very high137 Ų13783.3 Ų83.360%0.59641%0.408SS*.EExtended strand (participates in β ladder)trans-78.8-46.4171-178.9-179.8176.2-174.40110.8Q119 T121K98-Q119 WeakPolarHBondContact CB-O 3.42Å; K98-Q119 HydrophobicContact CD-CG 4.41Å; K98-Q119 PolarHBondContact N-O 2.88Å; K98-T121 HydrophobicContact CB-CG2 3.95Å
99K97.8Very high97.9Very high114 Ų11477.2 Ų77.250%0.49640%0.397SS..EExtended strand (participates in β ladder)trans-154.8141.8-176.9-172.1167.7174.2-176.90111.3F101 Q119K99-F101 HydrophobicContact CB-CD2 4.48Å; K99-F101 HydrophobicContact CB-CE2 3.77Å; K99-F101 HydrophobicContact CB-CZ 4.27Å; K99-F101 HydrophobicContact CD-CE1 4.06Å; K99-F101 HydrophobicContact CD-CE2 3.86Å; K99-F101 HydrophobicContact CD-CZ 3.48Å; K99-F101 VanDerWaalsContact CD-CZ 3.48Å; K99-F101 HydrophobicContact CG-CD2 4.2Å; K99-F101 HydrophobicContact CG-CE1 4.47Å; K99-F101 HydrophobicContact CG-CE2 3.64Å; K99-F101 HydrophobicContact CG-CZ 3.81Å; K99-Q119 PolarHBondContact N-O 2.89Å; K99-Q119 PolarHBondContact O-N 3.46Å
100E98.4Very high97.9Very high75 Ų7578.1 Ų78.135%0.3541%0.405SS..EExtended strand (participates in β ladder)trans-98.3139.4173.4-65.5-173.9-124.900110.4V97 K116 L118V97-E100 HydrophobicContact CG1-CG 3.91Å; E100-K116 HydrophobicContact CB-CD 4.24Å; E100-K116 WeakPolarHBondContact OE2-CD 3.48Å; E100-K116 WeakPolarHBondContact OE2-CE 3.28Å; E100-K116 IonicContact OE2-NZ 3.9Å; E100-K116 PolarHBondContact OE2-NZ 2.92Å; E100-L118 HydrophobicContact CB-CD2 4.47Å; E100-L118 HydrophobicContact CG-CD2 3.79Å
101F98.6Very high97.8Very high38 Ų3871.6 Ų71.617%0.16737%0.374CS..EExtended strand (participates in β ladder)trans-129.879.6176.5-62.3-96.6000108.1W63 K99 K116 L117 Q119 W253 T257 A261W63-F101 AromaticContact CH2-CD2 3.93Å; W63-F101 HydrophobicContact CH2-CD2 3.93Å; W63-F101 AromaticContact CH2-CE2 3.58Å; W63-F101 HydrophobicContact CH2-CE2 3.58Å; W63-F101 HydrophobicContact CH2-CZ 4.08Å; W63-F101 AromaticContact CZ3-CD2 3.73Å; W63-F101 HydrophobicContact CZ3-CD2 3.73Å; W63-F101 AromaticContact CZ3-CE2 3.85Å; W63-F101 HydrophobicContact CZ3-CE2 3.85Å; W63-F101 HydrophobicContact CZ3-CG 4.49Å; K99-F101 HydrophobicContact CB-CD2 4.48Å; K99-F101 HydrophobicContact CB-CE2 3.77Å; K99-F101 HydrophobicContact CB-CZ 4.27Å; K99-F101 HydrophobicContact CD-CE1 4.06Å; K99-F101 HydrophobicContact CD-CE2 3.86Å; K99-F101 HydrophobicContact CD-CZ 3.48Å; K99-F101 VanDerWaalsContact CD-CZ 3.48Å; K99-F101 HydrophobicContact CG-CD2 4.2Å; K99-F101 HydrophobicContact CG-CE1 4.47Å; K99-F101 HydrophobicContact CG-CE2 3.64Å; K99-F101 HydrophobicContact CG-CZ 3.81Å; F101-K116 WeakPolarHBondContact O-CA 3.28Å; F101-L117 HydrophobicContact CB-CB 4.05Å; F101-L117 PolarHBondContact N-O 2.04Å; F101-L117 PolarHBondContact O-N 2.91Å; F101-Q119 HydrophobicContact CD2-CB 4.5Å; F101-Q119 HydrophobicContact CE2-CB 3.89Å; F101-W253 VanDerWaalsContact O-CZ2 3.27Å; F101-W253 WeakPolarHBondContact O-CZ2 3.28Å; F101-T257 HydrophobicContact CB-CG2 3.91Å; F101-T257 HydrophobicContact CD1-CG2 3.66Å; F101-T257 HydrophobicContact CD2-CG2 4.38Å; F101-T257 HydrophobicContact CE1-CG2 4.19Å; F101-T257 HydrophobicContact CG-CG2 3.75Å; F101-A261 HydrophobicContact CZ-CB 3.94Å
102P98.5Very high97.8Very high69 Ų6971.6 Ų71.645%0.44837%0.374SS..EExtended strand (participates in β ladder)trans-62147.4169.627.9-33.7000109.6P104 K116P102-P104 WeakPolarHBondContact O-CD 3.42Å; P102-K116 HydrophobicContact CB-CD 4.33Å
103Y98.6Very high97.8Very high24 Ų2469.7 Ų69.79%0.09437%0.366CS..  trans-58.5124.3173.6179.7-118.2000109.1C105 Y106 G113 L115 K249 Y250 W253Y103-C105 HydrophobicContact CD1-CB 4.17Å; Y103-C105 HydrophobicContact CE1-CB 3.54Å; Y103-C105 PolarHBondContact O-N 2.86Å; Y103-Y106 WeakPolarHBondContact O-CB 3.13Å; Y103-Y106 PolarHBondContact O-N 2.79Å; Y103-G113 WeakPolarHBondContact CB-O 3.03Å; Y103-G113 WeakPolarHBondContact CD1-O 3.26Å; Y103-L115 WeakPolarHBondContact CB-O 3.39Å; Y103-L115 PolarHBondContact N-O 3.45Å; Y103-K249 WeakPolarHBondContact OH-CD 3.22Å; Y103-K249 VanDerWaalsContact OH-CE 3.32Å; Y103-K249 WeakPolarHBondContact OH-CE 3.48Å; Y103-Y250 HydrophobicContact CD1-CD1 4.37Å; Y103-Y250 AromaticContact CD1-CE1 3.87Å; Y103-Y250 HydrophobicContact CD1-CE1 3.87Å; Y103-Y250 HydrophobicContact CD2-CD1 4.25Å; Y103-Y250 HydrophobicContact CE1-CD1 4.09Å; Y103-Y250 AromaticContact CE1-CE1 3.47Å; Y103-Y250 HydrophobicContact CE1-CE1 3.47Å; Y103-Y250 VanDerWaalsContact CE1-CE1 3.47Å; Y103-Y250 AromaticContact CE2-CD1 3.98Å; Y103-Y250 HydrophobicContact CE2-CD1 3.98Å; Y103-Y250 HydrophobicContact CE2-CE1 4.21Å; Y103-Y250 HydrophobicContact CG-CD1 4.44Å; Y103-Y250 HydrophobicContact CG-CE1 4.37Å; Y103-Y250 AromaticContact CZ-CD1 3.88Å; Y103-Y250 AromaticContact CZ-CE1 3.66Å; Y103-W253 HydrophobicContact CD2-CB 4.24Å; Y103-W253 AromaticContact CD2-CD1 3.9Å; Y103-W253 AromaticContact CD2-CD2 3.53Å; Y103-W253 HydrophobicContact CD2-CD2 3.53Å; Y103-W253 AromaticContact CD2-CE2 3.83Å; Y103-W253 AromaticContact CD2-CE3 3.92Å; Y103-W253 HydrophobicContact CD2-CE3 3.92Å; Y103-W253 AromaticContact CD2-CG 3.61Å; Y103-W253 HydrophobicContact CD2-CG 3.61Å; Y103-W253 HydrophobicContact CD2-CZ2 4.48Å; Y103-W253 HydrophobicContact CE2-CB 4.02Å; Y103-W253 HydrophobicContact CE2-CD2 4.22Å; Y103-W253 AromaticContact CE2-CG 3.84Å; Y103-W253 HydrophobicContact CE2-CG 3.84Å
104P98Very high97.8Very high103 Ų10368.3 Ų68.367%0.66936%0.359SS*.THydrogen-bonded Turntrans-61.1-21.9-170.8-27.834.8000115P102P102-P104 WeakPolarHBondContact O-CD 3.42Å
105C98Very high97.8Very high86 Ų8663.3 Ų63.358%0.58133%0.334SS*.THydrogen-bonded Turntrans-111.327.5178.8-49.10000111.8Y103 D107Y103-C105 HydrophobicContact CD1-CB 4.17Å; Y103-C105 HydrophobicContact CE1-CB 3.54Å; Y103-C105 PolarHBondContact O-N 2.86Å; C105-D107 PolarHBondContact O-N 3.29Å
106Y98.3Very high97.9Very high56 Ų5662.9 Ų62.922%0.2233%0.332CS..  trans-63.9124.8168.2167.4-127.9000109.5A68 Y103 P108 E112 D114A68-Y106 HydrophobicContact CB-CD1 3.5Å; A68-Y106 VanDerWaalsContact CB-CD1 3.5Å; A68-Y106 HydrophobicContact CB-CD2 4.15Å; A68-Y106 HydrophobicContact CB-CE1 3.79Å; A68-Y106 HydrophobicContact CB-CE2 4.4Å; A68-Y106 HydrophobicContact CB-CG 3.69Å; Y103-Y106 WeakPolarHBondContact O-CB 3.13Å; Y103-Y106 PolarHBondContact O-N 2.79Å; Y106-P108 HydrophobicContact CE1-CB 4Å; Y106-P108 WeakPolarHBondContact OH-CA 3.5Å; Y106-E112 WeakPolarHBondContact CA-O 2.91Å; Y106-D114 VanDerWaalsContact CD2-CA 3.43Å; Y106-D114 HydrophobicContact CD2-CB 3.87Å; Y106-D114 HydrophobicContact CE2-CB 3.61Å
107D98.1Very high97.9Very high63 Ų6354 Ų5434%0.33730%0.298SS..BIsolated β-bridgetrans-108.1109.7173.7176.84000109.9C105 A109 T110 H111 E112C105-D107 PolarHBondContact O-N 3.29Å; D107-A109 PolarHBondContact O-N 3.15Å; D107-A109 WeakPolarHBondContact OD1-CB 3.32Å; D107-A109 PolarHBondContact OD1-N 3.29Å; D107-T110 WeakPolarHBondContact CB-OG1 3.46Å; D107-T110 PolarHBondContact O-N 3.06Å; D107-T110 WeakPolarHBondContact OD2-CG2 3.04Å; D107-T110 PolarHBondContact OD2-OG1 2.97Å; D107-H111 WeakPolarHBondContact O-CA 3.31Å; D107-H111 PolarHBondContact O-N 3.38Å; D107-E112 HydrophobicContact CB-CB 4.39Å; D107-E112 PolarHBondContact N-O 3.45Å; D107-E112 PolarHBondContact O-N 3.46Å
108P96.4Very high98Very high85 Ų8552.2 Ų52.255%0.55229%0.287SS*.THydrogen-bonded Turntrans-70.2-16.9-179.329.3-35.3000114.1Y106Y106-P108 HydrophobicContact CE1-CB 4Å; Y106-P108 WeakPolarHBondContact OH-CA 3.5Å
109A95.3Very high98.1Very high84 Ų8446.3 Ų46.369%0.69426%0.262SS*.THydrogen-bonded Turntrans-78.6-35.1178.300000111.9D107D107-A109 PolarHBondContact O-N 3.15Å; D107-A109 WeakPolarHBondContact OD1-CB 3.32Å; D107-A109 PolarHBondContact OD1-N 3.29Å
110T96.6Very high98.1Very high52 Ų5241 Ų4132%0.31924%0.239SC..THydrogen-bonded Turntrans-105.8-10.2-178.359.60000113.4D107 E112D107-T110 WeakPolarHBondContact CB-OG1 3.46Å; D107-T110 PolarHBondContact O-N 3.06Å; D107-T110 WeakPolarHBondContact OD2-CG2 3.04Å; D107-T110 PolarHBondContact OD2-OG1 2.97Å; T110-E112 PolarHBondContact O-N 3.32Å; T110-E112 WeakPolarHBondContact OG1-CB 3.32Å; T110-E112 PolarHBondContact OG1-N 3.26Å
111H97.3Very high98.1Very high53 Ų5340.8 Ų40.825%0.24524%0.243CC..THydrogen-bonded Turntrans61.912.4-168.1-56.5-83.8000114.3D107 G113 D114 M195 F228 I244D107-H111 WeakPolarHBondContact O-CA 3.31Å; D107-H111 PolarHBondContact O-N 3.38Å; H111-G113 PolarHBondContact O-N 2.97Å; H111-D114 WeakPolarHBondContact O-CB 3.18Å; H111-D114 PolarHBondContact O-N 3.07Å; H111-M195 VanDerWaalsContact C-CE 3.5Å; H111-M195 WeakPolarHBondContact O-CE 3.31Å; H111-F228 HydrophobicContact CB-CD1 3.52Å; H111-F228 HydrophobicContact CB-CE1 3.63Å; H111-F228 HydrophobicContact CB-CG 4.47Å; H111-F228 AromaticContact CD2-CD1 3.83Å; H111-F228 AromaticContact CD2-CG 4Å; H111-F228 AromaticContact CG-CD1 3.61Å; H111-I244 WeakPolarHBondContact O-CD1 3.43Å
112E98.2Very high98Very high50 Ų5045.7 Ų45.723%0.23427%0.266CS..BIsolated β-bridgetrans-62.8126.8177.7-176.886.8-158.100110.3Y106 D107 T110 D114 N194 M195 K249Y106-E112 WeakPolarHBondContact CA-O 2.91Å; D107-E112 HydrophobicContact CB-CB 4.39Å; D107-E112 PolarHBondContact N-O 3.45Å; D107-E112 PolarHBondContact O-N 3.46Å; T110-E112 PolarHBondContact O-N 3.32Å; T110-E112 WeakPolarHBondContact OG1-CB 3.32Å; T110-E112 PolarHBondContact OG1-N 3.26Å; E112-D114 VanDerWaalsContact C-N 3.32Å; E112-D114 PolarHBondContact O-N 2.92Å; E112-N194 VanDerWaalsContact OE1-CB 3.31Å; E112-N194 WeakPolarHBondContact OE1-CB 3.19Å; E112-N194 PolarHBondContact OE1-ND2 3.13Å; E112-M195 VanDerWaalsContact CA-CE 3.42Å; E112-M195 HydrophobicContact CB-CE 4.12Å; E112-K249 IonicContact OE1-NZ 3.55Å
113G98.3Very high98Very high0 Ų048.4 Ų48.40%027%0.271CS..THydrogen-bonded Turntrans66.929.6177.100000114.8Y103 H111 L115 Y250Y103-G113 WeakPolarHBondContact CB-O 3.03Å; Y103-G113 WeakPolarHBondContact CD1-O 3.26Å; H111-G113 PolarHBondContact O-N 2.97Å; G113-L115 PolarHBondContact O-N 3.18Å; G113-Y250 WeakPolarHBondContact CA-OH 3.43Å; G113-Y250 PolarHBondContact N-OH 3.22Å
114D98.8Very high98Very high0 Ų047.5 Ų47.50%027%0.269CS..  trans-64.573.2174.9-176.423.8000112.9A68 H69 Y106 H111 E112 S227 I244A68-D114 WeakPolarHBondContact CA-OD1 3.24Å; A68-D114 WeakPolarHBondContact CB-OD1 3.38Å; A68-D114 PolarHBondContact N-OD1 3.43Å; H69-D114 IonicContact CE1-OD2 3.98Å; H69-D114 PolarHBondContact CE1-OD2 3.02Å; H69-D114 IonicContact CG-OD1 3.77Å; H69-D114 IonicContact CG-OD2 3.8Å; H69-D114 PolarHBondContact N-OD1 3.44Å; H69-D114 VanDerWaalsContact ND1-CG 3.33Å; H69-D114 IonicContact ND1-OD1 3.72Å; H69-D114 PolarHBondContact ND1-OD1 3.5Å; H69-D114 IonicContact ND1-OD2 2.77Å; H69-D114 PolarHBondContact ND1-OD2 2.64Å; Y106-D114 VanDerWaalsContact CD2-CA 3.43Å; Y106-D114 HydrophobicContact CD2-CB 3.87Å; Y106-D114 HydrophobicContact CE2-CB 3.61Å; H111-D114 WeakPolarHBondContact O-CB 3.18Å; H111-D114 PolarHBondContact O-N 3.07Å; E112-D114 VanDerWaalsContact C-N 3.32Å; E112-D114 PolarHBondContact O-N 2.92Å; D114-S227 WeakPolarHBondContact CB-OG 3.41Å; D114-S227 WeakPolarHBondContact OD2-CB 3.37Å; D114-S227 PolarHBondContact OD2-OG 3.03Å; D114-I244 HydrophobicContact CB-CD1 3.96Å; D114-I244 HydrophobicContact CB-CG1 3.91Å
115L98.9Very high98.1Very high0 Ų050.4 Ų50.40%027%0.271CS..  trans-136141.5-177.1-69.5172.6000110L65 Y103 G113 V225 I244 Y250 W253L65-L115 HydrophobicContact CD1-CD2 4.31Å; Y103-L115 WeakPolarHBondContact CB-O 3.39Å; Y103-L115 PolarHBondContact N-O 3.45Å; G113-L115 PolarHBondContact O-N 3.18Å; L115-V225 HydrophobicContact CD2-CB 3.62Å; L115-V225 HydrophobicContact CD2-CG1 4.03Å; L115-V225 HydrophobicContact CD2-CG2 3.53Å; L115-I244 HydrophobicContact CD1-CG2 3.77Å; L115-I244 HydrophobicContact CD2-CB 4.15Å; L115-I244 HydrophobicContact CD2-CG2 4.27Å; L115-I244 HydrophobicContact CG-CB 4.19Å; L115-I244 HydrophobicContact CG-CG1 4.49Å; L115-I244 HydrophobicContact CG-CG2 3.85Å; L115-Y250 HydrophobicContact CD1-CD1 3.59Å; L115-Y250 HydrophobicContact CD1-CD2 4.12Å; L115-Y250 HydrophobicContact CD1-CE1 4.17Å; L115-Y250 HydrophobicContact CD1-CG 3.55Å; L115-W253 HydrophobicContact CB-CH2 4.39Å; L115-W253 HydrophobicContact CB-CZ3 3.96Å
116K98.9Very high98.1Very high7 Ų749.9 Ų49.93%0.0326%0.261CS..EExtended strand (participates in β ladder)trans-144.4136.2173.9174.2163.163.8177.80111T66 A68 C70 E100 F101 P102 L118T66-K116 HydrophobicContact CG2-CB 4.25Å; T66-K116 PolarHBondContact N-O 2.94Å; T66-K116 PolarHBondContact O-N 2.78Å; A68-K116 HydrophobicContact CB-CB 4.32Å; A68-K116 PolarHBondContact O-NZ 2.84Å; C70-K116 WeakPolarHBondContact O-CE 3.23Å; C70-K116 PolarHBondContact O-NZ 2.99Å; E100-K116 HydrophobicContact CB-CD 4.24Å; E100-K116 WeakPolarHBondContact OE2-CD 3.48Å; E100-K116 WeakPolarHBondContact OE2-CE 3.28Å; E100-K116 IonicContact OE2-NZ 3.9Å; E100-K116 PolarHBondContact OE2-NZ 2.92Å; F101-K116 WeakPolarHBondContact O-CA 3.28Å; P102-K116 HydrophobicContact CB-CD 4.33Å; K116-L118 HydrophobicContact CD-CD2 4.1Å; K116-L118 HydrophobicContact CG-CD2 3.98Å
117L98.9Very high98.1Very high0 Ų050.3 Ų50.30%027%0.267CS..EExtended strand (participates in β ladder)trans-96137169.1-75.1171.7000109.8I59 W63 V64 L65 F101 W253 I254 T257 I258I59-L117 HydrophobicContact CD1-CD2 3.53Å; I59-L117 HydrophobicContact CG1-CD2 4.48Å; W63-L117 HydrophobicContact CE3-CB 3.98Å; W63-L117 HydrophobicContact CE3-CD1 4.36Å; W63-L117 HydrophobicContact CE3-CD2 4.32Å; W63-L117 HydrophobicContact CE3-CG 4.47Å; W63-L117 HydrophobicContact CZ3-CB 3.91Å; W63-L117 HydrophobicContact CZ3-CD1 4.28Å; V64-L117 CarbonylContact O-C 3.56Å; V64-L117 WeakPolarHBondContact O-CA 3.33Å; L65-L117 HydrophobicContact CB-CD2 4.17Å; L65-L117 HydrophobicContact CD1-CD2 3.78Å; L65-L117 HydrophobicContact CD1-CG 4.2Å; F101-L117 HydrophobicContact CB-CB 4.05Å; F101-L117 PolarHBondContact N-O 2.04Å; F101-L117 PolarHBondContact O-N 2.91Å; L117-W253 HydrophobicContact CB-CH2 4.25Å; L117-W253 HydrophobicContact CD1-CH2 3.97Å; L117-W253 HydrophobicContact CD1-CZ2 4.22Å; L117-W253 HydrophobicContact CD1-CZ3 4.26Å; L117-W253 HydrophobicContact CG-CH2 3.73Å; L117-W253 HydrophobicContact CG-CZ2 4.35Å; L117-W253 HydrophobicContact CG-CZ3 4.13Å; L117-I254 HydrophobicContact CD1-CB 4.43Å; L117-I254 HydrophobicContact CD1-CG1 4.45Å; L117-I254 HydrophobicContact CD1-CG2 4.25Å; L117-I254 HydrophobicContact CD2-CG2 4.3Å; L117-T257 HydrophobicContact CD1-CG2 3.71Å; L117-I258 HydrophobicContact CD1-CG1 4.42Å
118L98.8Very high98.1Very high0 Ų055.2 Ų55.20%029%0.286CS..EExtended strand (participates in β ladder)trans-112.7116.4172-49.8176.2000107.8L46 W63 V64 T66 L72 V78 V97 E100 K116L46-L118 HydrophobicContact CD1-CD1 4.21Å; L46-L118 HydrophobicContact CD2-CD1 3.9Å; W63-L118 WeakPolarHBondContact CA-O 3.17Å; V64-L118 HydrophobicContact CB-CB 4.23Å; V64-L118 HydrophobicContact CB-CD1 4.46Å; V64-L118 HydrophobicContact CG1-CD1 4.37Å; V64-L118 PolarHBondContact N-O 2.86Å; V64-L118 PolarHBondContact O-N 2.78Å; T66-L118 HydrophobicContact CG2-CD1 3.97Å; T66-L118 HydrophobicContact CG2-CD2 4.45Å; T66-L118 HydrophobicContact CG2-CG 4.02Å; L72-L118 HydrophobicContact CD1-CD2 4.3Å; L72-L118 HydrophobicContact CD2-CD1 3.98Å; L72-L118 HydrophobicContact CD2-CD2 4.1Å; V78-L118 HydrophobicContact CG2-CD1 4.27Å; V97-L118 HydrophobicContact CG1-CB 4.3Å; V97-L118 HydrophobicContact CG1-CD2 4.35Å; V97-L118 HydrophobicContact CG2-CB 4.16Å; V97-L118 HydrophobicContact CG2-CD1 4.17Å; V97-L118 HydrophobicContact CG2-CD2 4.48Å; E100-L118 HydrophobicContact CB-CD2 4.47Å; E100-L118 HydrophobicContact CG-CD2 3.79Å; K116-L118 HydrophobicContact CD-CD2 4.1Å; K116-L118 HydrophobicContact CG-CD2 3.98Å
119Q98.6Very high98.2Very high13 Ų1354.9 Ų54.96%0.06127%0.274CS..EExtended strand (participates in β ladder)trans-83.6125.9167.9-172.5178.837.500108.2D62 W63 K98 K99 F101D62-Q119 CarbonylContact O-C 3.56Å; D62-Q119 WeakPolarHBondContact O-CA 3.08Å; W63-Q119 HydrophobicContact CD2-CB 4.49Å; W63-Q119 HydrophobicContact CE3-CB 4.22Å; W63-Q119 HydrophobicContact CH2-CB 3.79Å; W63-Q119 HydrophobicContact CH2-CG 4.1Å; W63-Q119 HydrophobicContact CZ2-CB 4.02Å; W63-Q119 HydrophobicContact CZ2-CG 3.82Å; W63-Q119 HydrophobicContact CZ3-CB 3.89Å; K98-Q119 WeakPolarHBondContact CB-O 3.42Å; K98-Q119 HydrophobicContact CD-CG 4.41Å; K98-Q119 PolarHBondContact N-O 2.88Å; K99-Q119 PolarHBondContact N-O 2.89Å; K99-Q119 PolarHBondContact O-N 3.46Å; F101-Q119 HydrophobicContact CD2-CB 4.5Å; F101-Q119 HydrophobicContact CE2-CB 3.89Å
120L98.6Very high98.4Very high3 Ų350.9 Ų50.92%0.01624%0.241CC..EExtended strand (participates in β ladder)trans-81.6155.2180-53.3-176.3000111L58 D62 V64 V78 M95 R96 E122L58-L120 HydrophobicContact CD1-CD1 4.38Å; D62-L120 HydrophobicContact CB-CB 4.37Å; D62-L120 PolarHBondContact O-N 2.98Å; V64-L120 HydrophobicContact CG2-CD1 4.24Å; V64-L120 HydrophobicContact CG2-CD2 4.16Å; V64-L120 HydrophobicContact CG2-CG 4.46Å; V78-L120 HydrophobicContact CB-CD2 4.17Å; V78-L120 HydrophobicContact CG1-CD2 3.92Å; V78-L120 HydrophobicContact CG2-CD2 4.01Å; M95-L120 HydrophobicContact CB-CD1 4.18Å; M95-L120 HydrophobicContact CB-CD2 4.4Å; M95-L120 HydrophobicContact CE-CB 4.48Å; M95-L120 HydrophobicContact CE-CD1 4.09Å; M95-L120 HydrophobicContact CG-CD1 4.22Å; R96-L120 WeakPolarHBondContact O-CA 3.4Å; L120-E122 VanDerWaalsContact C-N 3.25Å; L120-E122 WeakPolarHBondContact CB-O 3.24Å; L120-E122 PolarHBondContact O-N 2.88Å
121T97.4Very high98.5Very high71 Ų7150.4 Ų50.444%0.43624%0.238SC..SBendtrans-67.6-29.3176.251.90000112.8R96 K98R96-T121 HydrophobicContact CB-CG2 3.93Å; R96-T121 PolarHBondContact O-N 3.23Å; R96-T121 PolarHBondContact O-OG1 3.48Å; K98-T121 HydrophobicContact CB-CG2 3.95Å
122E97.8Very high98.6Very high140 Ų14050.2 Ų50.265%0.65424%0.238SC*.SBendtrans-139.1161.3-178.6-63179.9-174.300109.2M95 L120M95-E122 HydrophobicContact CE-CB 4.15Å; M95-E122 WeakPolarHBondContact CE-O 3.46Å; L120-E122 VanDerWaalsContact C-N 3.25Å; L120-E122 WeakPolarHBondContact CB-O 3.24Å; L120-E122 PolarHBondContact O-N 2.88Å
123K98.6Very high98.6Very high127 Ų12748.6 Ų48.655%0.55223%0.231SC*.  trans-76.7137.2174.3-73.1174.3160.2-139.30110.9E61 D62E61-K123 HydrophobicContact CB-CB 4.01Å; E61-K123 HydrophobicContact CB-CD 4.44Å; E61-K123 HydrophobicContact CB-CG 4.01Å; E61-K123 VanDerWaalsContact OE2-CD 3.3Å; E61-K123 WeakPolarHBondContact OE2-CD 3.46Å; E61-K123 WeakPolarHBondContact OE2-CE 3.32Å; E61-K123 IonicContact OE2-NZ 2.74Å; E61-K123 PolarHBondContact OE2-NZ 3.13Å; D62-K123 HydrophobicContact CB-CG 4.07Å
124A98.7Very high98.6Very high5 Ų555.6 Ų55.64%0.04126%0.264CS..  trans-63.8141.8169.900000110.9L58 E61 L80 I126 V130L58-A124 HydrophobicContact CD2-CB 4.11Å; E61-A124 VanDerWaalsContact O-CB 3.22Å; E61-A124 WeakPolarHBondContact O-CB 3.44Å; E61-A124 PolarHBondContact O-N 2.78Å; L80-A124 HydrophobicContact CD1-CB 3.4Å; A124-I126 HydrophobicContact CB-CD1 4.36Å; A124-I126 PolarHBondContact O-N 2.89Å; A124-V130 HydrophobicContact CB-CG1 4.23Å
125K98.8Very high98.6Very high164 Ų16457.8 Ų57.871%0.71328%0.275SS*.  trans-81.896.7172.6-62.6179.8-177177.20108.9Q93 N127Q93-K125 PolarHBondContact NE2-O 2.89Å; K125-N127 PolarHBondContact O-N 2.84Å; K125-N127 PolarHBondContact O-ND2 2.9Å
126I98.8Very high98.6Very high74 Ų7458.4 Ų58.438%0.37928%0.279SS..  trans-62.5129.6-179.8-55.6-53.5000110.4L58 E61 A124 V130 I132L58-I126 HydrophobicContact CD2-CD1 4.04Å; E61-I126 HydrophobicContact CG-CD1 4.32Å; E61-I126 HydrophobicContact CG-CG1 4.01Å; A124-I126 HydrophobicContact CB-CD1 4.36Å; A124-I126 PolarHBondContact O-N 2.89Å; I126-V130 WeakPolarHBondContact CA-O 3.41Å; I126-V130 HydrophobicContact CD1-CG1 4.4Å; I126-V130 WeakPolarHBondContact CG2-O 3.22Å; I126-I132 HydrophobicContact CD1-CD1 4.22Å; I126-I132 HydrophobicContact CD1-CG1 4.02Å; I126-I132 HydrophobicContact CG1-CD1 4.5Å
127N98.6Very high98.3Very high66 Ų6668.3 Ų68.335%0.35332%0.322SS..BIsolated β-bridgetrans-157.1-169.5-179.865.647.8000110.5Q93 K125 Y129 V130Q93-N127 PolarHBondContact NE2-ND2 2.75Å; K125-N127 PolarHBondContact O-N 2.84Å; K125-N127 PolarHBondContact O-ND2 2.9Å; N127-Y129 PolarHBondContact O-N 3.32Å; N127-Y129 VanDerWaalsContact O-N 3.14Å; N127-Y129 WeakPolarHBondContact OD1-CA 3.24Å; N127-Y129 WeakPolarHBondContact OD1-CB 3.28Å; N127-Y129 PolarHBondContact OD1-N 2.92Å; N127-V130 PolarHBondContact N-O 2.8Å; N127-V130 CarbonylContact O-C 3.44Å; N127-V130 PolarHBondContact O-N 2.54Å; N127-V130 PolarHBondContact OD1-N 2.91Å; N127-V130 VanDerWaalsContact OD1-N 3.12Å
128K98.6Very high98.1Very high166 Ų16675 Ų7572%0.72235%0.351SS*.THydrogen-bonded Turntrans-56.9-28.2180-176.9-179.7173.6-171.60114
129Y98.7Very high98Very high78 Ų7876 Ų7631%0.30636%0.362SS..THydrogen-bonded Turntrans-106.8-10.8-173.1-45.1-62000113.2H38 P41 G81 E91 N127H38-Y129 HydrophobicContact CB-CD1 3.6Å; H38-Y129 HydrophobicContact CB-CE1 4.43Å; H38-Y129 HydrophobicContact CB-CG 4.32Å; H38-Y129 AromaticContact CG-CD1 3.96Å; P41-Y129 WeakPolarHBondContact CA-O 3.33Å; P41-Y129 VanDerWaalsContact CB-O 3.28Å; P41-Y129 WeakPolarHBondContact CB-O 3.5Å; G81-Y129 WeakPolarHBondContact CA-O 3.32Å; E91-Y129 HydrophobicContact CB-CD2 4.04Å; E91-Y129 HydrophobicContact CB-CG 4.13Å; E91-Y129 HydrophobicContact CG-CD1 4.23Å; E91-Y129 HydrophobicContact CG-CD2 3.35Å; E91-Y129 HydrophobicContact CG-CE1 4.49Å; E91-Y129 HydrophobicContact CG-CE2 3.66Å; E91-Y129 HydrophobicContact CG-CG 3.64Å; N127-Y129 PolarHBondContact O-N 3.32Å; N127-Y129 VanDerWaalsContact O-N 3.14Å; N127-Y129 WeakPolarHBondContact OD1-CA 3.24Å; N127-Y129 WeakPolarHBondContact OD1-CB 3.28Å; N127-Y129 PolarHBondContact OD1-N 2.92Å
130V98.9Very high97.9Very high0 Ų079.2 Ų79.20%038%0.379CS..BIsolated β-bridgetrans-133.2107.5178-1790000109.1P41 L58 L80 Q93 A124 I126 N127P41-V130 CarbonylContact O-C 3.54Å; P41-V130 VanDerWaalsContact O-CA 3.31Å; P41-V130 WeakPolarHBondContact O-CA 3.3Å; L58-V130 HydrophobicContact CD2-CG1 3.76Å; L80-V130 HydrophobicContact CB-CG1 4.04Å; L80-V130 HydrophobicContact CB-CG2 4.02Å; L80-V130 HydrophobicContact CD1-CG1 4.03Å; Q93-V130 HydrophobicContact CG-CG2 4.49Å; A124-V130 HydrophobicContact CB-CG1 4.23Å; I126-V130 WeakPolarHBondContact CA-O 3.41Å; I126-V130 HydrophobicContact CD1-CG1 4.4Å; I126-V130 WeakPolarHBondContact CG2-O 3.22Å; N127-V130 PolarHBondContact N-O 2.8Å; N127-V130 CarbonylContact O-C 3.44Å; N127-V130 PolarHBondContact O-N 2.54Å; N127-V130 PolarHBondContact OD1-N 2.91Å; N127-V130 VanDerWaalsContact OD1-N 3.12Å
131T98.9Very high97.9Very high41 Ų4182.7 Ų82.725%0.25240%0.398SS..  trans-130.9159.2-176.663.40000112P41 Y42P41-T131 HydrophobicContact CB-CG2 3.85Å; P41-T131 HydrophobicContact CG-CG2 3.74Å; P41-T131 VanDerWaalsContact CG-OG1 3.31Å; P41-T131 WeakPolarHBondContact CG-OG1 3.11Å; P41-T131 PolarHBondContact O-N 3.3Å; Y42-T131 VanDerWaalsContact CA-O 3.27Å; Y42-T131 WeakPolarHBondContact CA-O 3.27Å; Y42-T131 WeakPolarHBondContact CB-O 3.37Å; Y42-T131 PolarHBondContact N-OG1 2.81Å
132I98.9Very high97.9Very high50 Ų5079.9 Ų79.926%0.25638%0.38SS..PPolyproline II helixtrans-86.6124.6175.3-67.2163.6000110.7L58 I59 E61 I126 H134L58-I132 HydrophobicContact CD2-CG1 4.46Å; L58-I132 CarbonylContact O-C 3.51Å; L58-I132 WeakPolarHBondContact O-CA 3.04Å; I59-I132 VanDerWaalsContact O-CG2 3.26Å; I59-I132 WeakPolarHBondContact O-CG2 3.32Å; E61-I132 HydrophobicContact CG-CD1 4.07Å; I126-I132 HydrophobicContact CD1-CD1 4.22Å; I126-I132 HydrophobicContact CD1-CG1 4.02Å; I126-I132 HydrophobicContact CG1-CD1 4.5Å; I132-H134 PolarHBondContact O-ND1 2.79Å; I132-H134 VanDerWaalsContact O-ND1 3.09Å
133L98.8Very high98Very high16 Ų1680.9 Ų80.98%0.08438%0.383CS..PPolyproline II helixtrans-80.7122.3166.7-175.663000109.8Y42 A57 L58 P215 L217 F222Y42-L133 HydrophobicContact CD1-CD1 4.19Å; Y42-L133 HydrophobicContact CD2-CB 4.23Å; Y42-L133 HydrophobicContact CD2-CD1 4.48Å; Y42-L133 HydrophobicContact CD2-CD2 3.88Å; Y42-L133 HydrophobicContact CD2-CG 4.44Å; Y42-L133 HydrophobicContact CE1-CD1 4.38Å; Y42-L133 HydrophobicContact CE2-CD2 4.18Å; Y42-L133 HydrophobicContact CG-CB 3.88Å; Y42-L133 HydrophobicContact CG-CD1 4.23Å; Y42-L133 HydrophobicContact CG-CD2 4.31Å; Y42-L133 HydrophobicContact CG-CG 4.38Å; A57-L133 HydrophobicContact CB-CB 4.48Å; A57-L133 HydrophobicContact CB-CD2 3.91Å; L58-L133 PolarHBondContact O-N 3.11Å; L133-P215 HydrophobicContact CD2-CB 3.64Å; L133-P215 HydrophobicContact CD2-CG 4.04Å; L133-L217 HydrophobicContact CD1-CD1 4.36Å; L133-L217 HydrophobicContact CD1-CD2 4.15Å; L133-L217 HydrophobicContact CD2-CD2 3.86Å; L133-F222 HydrophobicContact CD1-CB 4.38Å; L133-F222 HydrophobicContact CD2-CB 3.91Å; L133-F222 HydrophobicContact CD2-CD1 3.34Å; L133-F222 HydrophobicContact CD2-CD2 4.11Å; L133-F222 HydrophobicContact CD2-CE1 3.74Å; L133-F222 HydrophobicContact CD2-CE2 4.45Å; L133-F222 HydrophobicContact CD2-CG 3.54Å; L133-F222 HydrophobicContact CD2-CZ 4.28Å; L133-F222 HydrophobicContact CG-CB 4.02Å; L133-F222 HydrophobicContact CG-CD1 3.66Å; L133-F222 HydrophobicContact CG-CE1 4.34Å; L133-F222 HydrophobicContact CG-CG 4.04Å
134H98.6Very high97.9Very high147 Ų14777.6 Ų77.668%0.68137%0.374SS*.PPolyproline II helixtrans-78.5136.5-174.9-67.151.1000110.8I132I132-H134 PolarHBondContact O-ND1 2.79Å; I132-H134 VanDerWaalsContact O-ND1 3.09Å
135L98.6Very high97.9Very high45 Ų4580 Ų8024%0.23640%0.399CS..PPolyproline II helixtrans-62.7147.7170.3-64.7173.6000110.5I59 F222 L246 L251 I254 I255I59-L135 HydrophobicContact CD1-CD2 4.49Å; I59-L135 HydrophobicContact CG2-CD2 4.28Å; L135-F222 HydrophobicContact CD2-CD1 4.5Å; L135-L246 HydrophobicContact CD2-CD1 4.44Å; L135-L251 HydrophobicContact CB-CD2 4.2Å; L135-L251 HydrophobicContact CD2-CD2 4.35Å; L135-I254 HydrophobicContact CD1-CB 4.44Å; L135-I254 HydrophobicContact CD1-CG2 3.58Å; L135-I254 HydrophobicContact CD2-CD1 4.22Å; L135-I254 HydrophobicContact CD2-CG2 4.42Å; L135-I255 HydrophobicContact CD1-CG1 4.45Å
136P97.5Very high97.9Very high13 Ų1373.4 Ų73.48%0.08437%0.373CS..PPolyproline II helixtrans-64.8141.2176.728.7-35.6000110.7K138 V221 F222 L246 L251P136-K138 PolarHBondContact O-N 2.8Å; P136-V221 HydrophobicContact CB-CG1 3.92Å; P136-F222 VanDerWaalsContact CD-O 3.28Å; P136-F222 WeakPolarHBondContact CD-O 3.43Å; P136-F222 VanDerWaalsContact CG-O 3.24Å; P136-F222 WeakPolarHBondContact CG-O 3.35Å; P136-L246 HydrophobicContact CG-CB 3.98Å; P136-L246 HydrophobicContact CG-CD1 4.12Å; P136-L251 HydrophobicContact CG-CD1 4.02Å; P136-L251 HydrophobicContact CG-CD2 3.84Å; P136-L251 HydrophobicContact CG-CG 4.49Å
137K93.8Very high97.9Very high215 Ų21575.9 Ų75.994%0.93539%0.385SS*.SBendtrans-63.9-28.3179-66-175.7179.5179.80113
138K95.1Very high97.9Very high140 Ų14072.8 Ų72.861%0.60937%0.368SS*.SBendtrans-135.8140.8179.2-64.1-177.4-179.1-179.20108.7P136 D140P136-K138 PolarHBondContact O-N 2.8Å; K138-D140 WeakPolarHBondContact CB-OD2 3.39Å; K138-D140 PolarHBondContact O-N 3.31Å
139G95.8Very high97.9Very high22 Ų2267.5 Ų67.523%0.22735%0.346CS..  trans-84.950.5174.700000112.4L246G139-L246 WeakPolarHBondContact CA-O 3.18Å
140D96.8Very high97.9Very high81 Ų8164 Ų6443%0.43333%0.332SS..PPolyproline II helixtrans-73.6143.3178-53.3-38.8000110K138 R223K138-D140 WeakPolarHBondContact CB-OD2 3.39Å; K138-D140 PolarHBondContact O-N 3.31Å; D140-R223 PolarHBondContact O-NH1 3.22Å; D140-R223 VanDerWaalsContact O-NH1 3.15Å
141D98.1Very high97.8Very high76 Ų7664 Ų6441%0.40633%0.333SS..PPolyproline II helixtrans-63.6158.2170.8-161.112000111R176 V196 L245D141-R176 VanDerWaalsContact CG-NH2 3.34Å; D141-R176 IonicContact OD1-CZ 3.85Å; D141-R176 IonicContact OD1-NH2 3.25Å; D141-R176 PolarHBondContact OD1-NH2 2.83Å; D141-R176 IonicContact OD2-CZ 2.76Å; D141-R176 IonicContact OD2-NH1 3.75Å; D141-R176 PolarHBondContact OD2-NH1 3.26Å; D141-R176 IonicContact OD2-NH2 3.61Å; D141-R176 PolarHBondContact OD2-NH2 2.92Å; D141-R176 VanDerWaalsContact OD2-NH2 3.08Å; D141-V196 WeakPolarHBondContact OD1-CG1 3.13Å; D141-L245 HydrophobicContact CB-CD2 4.31Å
142V98.2Very high97.8Very high11 Ų1162.1 Ų62.17%0.06732%0.321CS..PPolyproline II helixtrans-100.5127.6-179.5-162.60000109.4T146 I173 C218 R223 L245V142-T146 HydrophobicContact CG1-CG2 3.8Å; V142-I173 HydrophobicContact CB-CD1 4.03Å; V142-I173 HydrophobicContact CB-CG1 4.02Å; V142-I173 HydrophobicContact CG1-CD1 4.08Å; V142-I173 HydrophobicContact CG1-CG1 3.66Å; V142-C218 HydrophobicContact CG1-CB 4.14Å; V142-R223 HydrophobicContact CG2-CB 3.76Å; V142-R223 HydrophobicContact CG2-CG 3.73Å; V142-L245 HydrophobicContact CG2-CD1 4.21Å
143K98.4Very high97.7Very high162 Ų16259.8 Ų59.870%0.70431%0.309SS*.PPolyproline II helixtrans-63.8136.8-177.9-171.4-177.3175.3-177.60110.6T146K143-T146 VanDerWaalsContact O-CB 3.22Å; K143-T146 WeakPolarHBondContact O-CB 3.44Å; K143-T146 PolarHBondContact O-N 2.98Å; K143-T146 VanDerWaalsContact O-N 3.12Å; K143-T146 PolarHBondContact O-OG1 2.95Å
144P98.6Very high97.3Very high57 Ų5759 Ų5937%0.3731%0.305SS..THydrogen-bonded Turntrans-52.6141.7169.5-26.135.3000112.3T146 D175P144-T146 VanDerWaalsContact C-N 3.3Å; P144-D175 HydrophobicContact CB-CB 3.99Å; P144-D175 HydrophobicContact CG-CB 3.87Å; P144-D175 WeakPolarHBondContact CG-OD2 3.12Å
145G98.2Very high96.9Very high55 Ų5555.6 Ų55.657%0.56729%0.286SS*.THydrogen-bonded Turntrans84.5-5.8-17400000114.8M147 T172 I173G145-M147 PolarHBondContact O-N 3.46Å; G145-T172 VanDerWaalsContact CA-CG2 3.45Å; G145-I173 PolarHBondContact N-O 3.25Å
146T98.6Very high96Very high26 Ų2655.3 Ų55.316%0.1628%0.284CS..  trans-67.8130.2174.6-57.30000110V142 K143 P144 T172 I173 C218V142-T146 HydrophobicContact CG1-CG2 3.8Å; K143-T146 VanDerWaalsContact O-CB 3.22Å; K143-T146 WeakPolarHBondContact O-CB 3.44Å; K143-T146 PolarHBondContact O-N 2.98Å; K143-T146 VanDerWaalsContact O-N 3.12Å; K143-T146 PolarHBondContact O-OG1 2.95Å; P144-T146 VanDerWaalsContact C-N 3.3Å; T146-T172 WeakPolarHBondContact O-CA 3.36Å; T146-I173 PolarHBondContact O-N 2.97Å; T146-C218 HydrophobicContact CG2-CB 4.06Å
147M98.2Very high94.9Very high127 Ų12758.8 Ų58.863%0.62630%0.299SS*.EExtended strand (participates in β ladder)trans-75.3137.5172.2-67.1-169.2-62.200110.9G145G145-M147 PolarHBondContact O-N 3.46Å
148C98.6Very high93.8Very high0 Ų051.4 Ų51.40%027%0.27CS..EExtended strand (participates in β ladder)trans-138.1165.8178.9-51.60000110.2N170 I171 I173 L216 L217 C218C148-N170 WeakPolarHBondContact O-CA 3.21Å; C148-I171 HydrophobicContact CB-CG1 4.27Å; C148-I171 PolarHBondContact N-O 2.89Å; C148-I171 PolarHBondContact O-N 2.92Å; C148-I171 VanDerWaalsContact O-O 3.07Å; C148-I173 VanDerWaalsContact SG-CG1 3.6Å; C148-L216 HydrophobicContact CB-CD1 3.64Å; C148-L216 HydrophobicContact CB-CG 4.24Å; C148-L217 CarbonylContact C-O 3.58Å; C148-L217 WeakPolarHBondContact CA-O 3.34Å; C148-L217 WeakPolarHBondContact CB-O 3.47Å; C148-C218 HydrophobicContact CB-CB 4.01Å; C148-C218 WeakPolarHBondContact CB-SG 3.37Å; C148-C218 WeakPolarHBondContact SG-CB 3.29Å; C148-C218 CovalentContact SG-SG 2.04Å; C148-C218 PolarHBondContact SG-SG 3.35Å
149Q98.3Very high92.4Very high56 Ų5649.9 Ų49.926%0.26228%0.277SS..EExtended strand (participates in β ladder)trans-124.4145.5172.7-62.497.8-0.700110.4E168 V169 N170 L217Q149-E168 HydrophobicContact CB-CG 3.92Å; Q149-E168 HydrophobicContact CG-CG 4.32Å; Q149-V169 WeakPolarHBondContact CA-O 3.41Å; Q149-N170 VanDerWaalsContact CG-OD1 3.23Å; Q149-N170 WeakPolarHBondContact CG-OD1 3.46Å; Q149-N170 PolarHBondContact NE2-OD1 2.87Å; Q149-L217 PolarHBondContact N-O 2.8Å; Q149-L217 PolarHBondContact O-N 3.46Å; Q149-L217 PolarHBondContact OE1-O 2.89Å
150V98.2Very high91.3Very high3 Ų349.4 Ų49.42%0.01827%0.271CS..EExtended strand (participates in β ladder)trans-131.7135165.662.90000107.9E168 V169 I171 S214 Y243V150-E168 WeakPolarHBondContact O-CA 3.17Å; V150-V169 HydrophobicContact CG1-CG1 3.46Å; V150-V169 VanDerWaalsContact CG1-CG1 3.46Å; V150-V169 PolarHBondContact N-O 3.04Å; V150-V169 PolarHBondContact O-N 2.85Å; V150-I171 HydrophobicContact CB-CD1 4.31Å; V150-I171 HydrophobicContact CG1-CD1 3.78Å; V150-S214 WeakPolarHBondContact CG2-OG 3.4Å; V150-Y243 HydrophobicContact CB-CE1 4.33Å; V150-Y243 HydrophobicContact CG2-CE1 4.11Å
151A98.1Very high90.4Very high2 Ų250.1 Ų50.12%0.01728%0.283CS..EExtended strand (participates in β ladder)trans-117.5150.5178.900000110.8M43 L166 R167 E168 S214M43-A151 HydrophobicContact CE-CB 4.27Å; M43-A151 WeakPolarHBondContact CE-O 2.99Å; M43-A151 HydrophobicContact CG-CB 4.48Å; M43-A151 HydrophobicContact SD-CB 4.17Å; A151-L166 HydrophobicContact CB-CD1 4.14Å; A151-R167 CarbonylContact C-O 3.59Å; A151-R167 WeakPolarHBondContact CA-O 3.39Å; A151-R167 WeakPolarHBondContact CB-O 3.42Å; A151-E168 HydrophobicContact CB-CB 4.05Å; A151-E168 HydrophobicContact CB-CG 4.3Å; A151-S214 WeakPolarHBondContact O-CB 3.47Å; A151-S214 PolarHBondContact O-OG 2Å
152G97.6Very high89.7Confident0 Ų049.8 Ų49.80%028%0.279CS..EExtended strand (participates in β ladder)trans177.3-177.5176.600000113.8R167 D211G152-R167 PolarHBondContact N-O 3.13Å; G152-R167 PolarHBondContact O-N 3.47Å; G152-D211 VanDerWaalsContact CA-OD1 3.24Å; G152-D211 WeakPolarHBondContact CA-OD1 3.44Å
153W97.1Very high89.4Confident2 Ų249.7 Ų49.71%0.00828%0.278CS..SBendtrans-111.611.8-179.6-66.4-90.6000111.7M43 L45 I53 A82 H83 I85 Q162 S163 L166 D211M43-W153 HydrophobicContact CB-CH2 3.92Å; M43-W153 HydrophobicContact CB-CZ3 4.26Å; M43-W153 HydrophobicContact CE-CZ3 4.01Å; L45-W153 HydrophobicContact CB-CD2 4.46Å; L45-W153 HydrophobicContact CB-CE3 4.06Å; L45-W153 HydrophobicContact CB-CH2 3.98Å; L45-W153 HydrophobicContact CB-CZ2 4.38Å; L45-W153 HydrophobicContact CB-CZ3 3.8Å; L45-W153 HydrophobicContact CD1-CD2 4.12Å; L45-W153 HydrophobicContact CD1-CE3 3.98Å; L45-W153 HydrophobicContact CD1-CG 4.37Å; I53-W153 HydrophobicContact CD1-CB 3.68Å; I53-W153 WeakPolarHBondContact CD1-O 3.34Å; A82-W153 HydrophobicContact CB-CZ2 4.16Å; A82-W153 WeakPolarHBondContact O-CZ2 3.44Å; H83-W153 PolarHBondContact O-NE1 2.87Å; I85-W153 HydrophobicContact CD1-CB 4.01Å; I85-W153 HydrophobicContact CD1-CG 4.28Å; I85-W153 HydrophobicContact CG1-CB 4.39Å; I85-W153 HydrophobicContact CG1-CG 4.12Å; W153-Q162 WeakPolarHBondContact O-CB 3.23Å; W153-S163 PolarHBondContact O-N 3.44Å; W153-L166 HydrophobicContact CD2-CB 4.48Å; W153-L166 HydrophobicContact CD2-CD1 3.89Å; W153-L166 HydrophobicContact CE3-CD1 3.93Å; W153-L166 HydrophobicContact CH2-CD1 3.82Å; W153-L166 HydrophobicContact CH2-CD2 4.25Å; W153-L166 HydrophobicContact CH2-CG 4.44Å; W153-L166 HydrophobicContact CZ2-CB 3.76Å; W153-L166 HydrophobicContact CZ2-CD1 3.77Å; W153-L166 HydrophobicContact CZ2-CD2 4.09Å; W153-L166 HydrophobicContact CZ2-CG 4.08Å; W153-L166 HydrophobicContact CZ3-CD1 3.89Å; W153-D211 PolarHBondContact N-OD1 2.92Å
154G92.1Very high89.2Confident0 Ų044.6 Ų44.60%026%0.259CS..  trans-61.5-179.5179.900000113.6S163 D209 D211G154-S163 PolarHBondContact O-N 2.87Å; G154-S163 VanDerWaalsContact O-N 3.13Å; G154-D209 CarbonylContact C-O 3.43Å; G154-D209 WeakPolarHBondContact CA-O 3.01Å; G154-D211 VanDerWaalsContact CA-OD1 3.28Å; G154-D211 WeakPolarHBondContact CA-OD1 3.29Å; G154-D211 PolarHBondContact N-OD1 3Å
155R88.4Confident89.1Confident74 Ų7443 Ų4328%0.27925%0.248SC..BIsolated β-bridgetrans-61.3140.7-179.5-73.1-172178.9148.111.3112A160 C208 D209R155-A160 HydrophobicContact CB-CB 4.49Å; R155-A160 VanDerWaalsContact CD-O 3.22Å; R155-A160 WeakPolarHBondContact CD-O 3.39Å; R155-A160 WeakPolarHBondContact CG-O 3.34Å; R155-A160 PolarHBondContact NE-O 3.03Å; R155-A160 VanDerWaalsContact NE-O 3.13Å; R155-C208 HydrophobicContact CB-CB 4.33Å; R155-D209 HydrophobicContact CG-CB 4.21Å; R155-D209 IonicContact CZ-OD2 3.34Å; R155-D209 PolarHBondContact N-O 3.28Å; R155-D209 IonicContact NH1-OD2 3.62Å; R155-D209 PolarHBondContact NH1-OD2 3.36Å; R155-D209 IonicContact NH2-OD2 2.74Å
156I81Confident89.1Confident39 Ų3940.5 Ų40.520%0.222%0.222CC..SBendtrans-89.3-17.1179.956.9167.1000114.3E27 E28 A160E27-I156 WeakPolarHBondContact O-CD1 3.28Å; E28-I156 VanDerWaalsContact C-CB 3.48Å; E28-I156 CarbonylContact O-C 3.49Å; E28-I156 WeakPolarHBondContact O-CA 3.16Å; E28-I156 WeakPolarHBondContact O-CB 3.48Å; E28-I156 VanDerWaalsContact O-CG2 3.26Å; E28-I156 WeakPolarHBondContact O-CG2 3.11Å; I156-A160 HydrophobicContact CD1-CB 4.48Å; I156-A160 HydrophobicContact CG1-CB 3.5Å
157H74.3Confident89Confident86 Ų8640.7 Ų40.740%0.39822%0.219SC..SBendtrans-157.5163.9168.956.7-93.6000108.1S159 A160H157-S159 PolarHBondContact CD2-OG 2.93Å; H157-S159 PolarHBondContact NE2-OG 3.05Å; H157-S159 PolarHBondContact O-N 3.29Å; H157-A160 HydrophobicContact CB-CB 4.45Å; H157-A160 PolarHBondContact CD2-N 3.11Å; H157-A160 WeakPolarHBondContact CE1-CB 3.44Å; H157-A160 WeakPolarHBondContact ND1-CB 3.1Å; H157-A160 VanDerWaalsContact NE2-CA 3.29Å; H157-A160 WeakPolarHBondContact NE2-CA 3.47Å; H157-A160 WeakPolarHBondContact NE2-CB 3.22Å; H157-A160 PolarHBondContact NE2-N 3.08Å; H157-A160 VanDerWaalsContact O-CB 3.24Å; H157-A160 WeakPolarHBondContact O-CB 3.25Å; H157-A160 PolarHBondContact O-N 2.98Å
158N69.9Low89Confident60 Ų6036 Ų3632%0.32120%0.196SC..THydrogen-bonded Turntrans-59.8-26.7-171.2-73.4-57.9000114.1N232 R233 C234N158-N232 PolarHBondContact OD1-O 3.14Å; N158-R233 PolarHBondContact OD1-N 2.93Å; N158-C234 PolarHBondContact ND2-O 3.3Å; N158-C234 VanDerWaalsContact ND2-O 3.14Å; N158-C234 PolarHBondContact OD1-N 3.26Å
159S66.5Low88.9Confident109 Ų10936.1 Ų36.176%0.76220%0.196SC*.THydrogen-bonded Turntrans-98.45.6174.7570000115.1H157H157-S159 PolarHBondContact CD2-OG 2.93Å; H157-S159 PolarHBondContact NE2-OG 3.05Å; H157-S159 PolarHBondContact O-N 3.29Å
160A71.4Confident88.8Confident11 Ų1137.7 Ų37.79%0.09121%0.207CC..PPolyproline II helixtrans-81.9161.3-173.500000113.4R155 I156 H157R155-A160 HydrophobicContact CB-CB 4.49Å; R155-A160 VanDerWaalsContact CD-O 3.22Å; R155-A160 WeakPolarHBondContact CD-O 3.39Å; R155-A160 WeakPolarHBondContact CG-O 3.34Å; R155-A160 PolarHBondContact NE-O 3.03Å; R155-A160 VanDerWaalsContact NE-O 3.13Å; I156-A160 HydrophobicContact CD1-CB 4.48Å; I156-A160 HydrophobicContact CG1-CB 3.5Å; H157-A160 HydrophobicContact CB-CB 4.45Å; H157-A160 PolarHBondContact CD2-N 3.11Å; H157-A160 WeakPolarHBondContact CE1-CB 3.44Å; H157-A160 WeakPolarHBondContact ND1-CB 3.1Å; H157-A160 VanDerWaalsContact NE2-CA 3.29Å; H157-A160 WeakPolarHBondContact NE2-CA 3.47Å; H157-A160 WeakPolarHBondContact NE2-CB 3.22Å; H157-A160 PolarHBondContact NE2-N 3.08Å; H157-A160 VanDerWaalsContact O-CB 3.24Å; H157-A160 WeakPolarHBondContact O-CB 3.25Å; H157-A160 PolarHBondContact O-N 2.98Å
161S78.1Confident88.8Confident97 Ų9737.6 Ų37.668%0.67821%0.206SC*.PPolyproline II helixtrans-69.8166.3151.358.60000111.3
162Q84.4Confident88.8Confident69 Ų6940.2 Ų40.232%0.32222%0.222SC..BIsolated β-bridgetrans-56.1152.8168.2-66.5143.2-6.700110.8K51 I53 W153K51-Q162 PolarHBondContact O-NE2 3.22Å; K51-Q162 PolarHBondContact O-OE1 3.2Å; I53-Q162 HydrophobicContact CD1-CB 4Å; I53-Q162 HydrophobicContact CD1-CG 3.77Å; I53-Q162 HydrophobicContact CG1-CG 4.09Å; W153-Q162 WeakPolarHBondContact O-CB 3.23Å
163S91.9Very high88.9Confident9 Ų940.5 Ų40.56%0.06322%0.224CC..PPolyproline II helixtrans-71.7131.6171.8-173.40000110I85 W153 G154 T165 R167I85-S163 VanDerWaalsContact CD1-O 3.28Å; I85-S163 WeakPolarHBondContact CD1-O 3.26Å; W153-S163 PolarHBondContact O-N 3.44Å; G154-S163 PolarHBondContact O-N 2.87Å; G154-S163 VanDerWaalsContact O-N 3.13Å; S163-T165 WeakPolarHBondContact CB-O 3.42Å; S163-T165 PolarHBondContact OG-N 3.12Å; S163-T165 PolarHBondContact OG-O 2.9Å; S163-R167 WeakPolarHBondContact OG-CD 3.5Å
164D94Very high88.9Confident54 Ų5440.9 Ų40.929%0.28923%0.226SC..SBendtrans-68.9-39.5171.6-178.970.8000111.1S84 I85 T86S84-D164 CarbonylContact C-O 3.41Å; S84-D164 WeakPolarHBondContact CA-O 3.37Å; S84-D164 WeakPolarHBondContact CB-OD2 3.49Å; S84-D164 VanDerWaalsContact OG-CG 3.31Å; S84-D164 PolarHBondContact OG-OD1 3.06Å; S84-D164 PolarHBondContact OG-OD2 3.44Å; I85-D164 PolarHBondContact N-O 3.38Å; I85-D164 PolarHBondContact N-OD1 2.69Å; T86-D164 VanDerWaalsContact CB-OD1 3.28Å; T86-D164 WeakPolarHBondContact CB-OD1 2.88Å; T86-D164 VanDerWaalsContact CG2-OD1 3.23Å; T86-D164 WeakPolarHBondContact CG2-OD1 2.83Å; T86-D164 PolarHBondContact N-OD1 3.14Å; T86-D164 PolarHBondContact OG1-OD1 2.87Å
165T96.7Very high89.2Confident25 Ų2543.6 Ų43.615%0.15324%0.24CC..BIsolated β-bridgetrans-95.8152.9-179.7520000111.9E34 H83 S163 R167E34-T165 VanDerWaalsContact CD-OG1 3.25Å; E34-T165 PolarHBondContact OE2-OG1 2.76Å; H83-T165 CarbonylContact O-C 3.5Å; H83-T165 WeakPolarHBondContact O-CA 3.44Å; S163-T165 WeakPolarHBondContact CB-O 3.42Å; S163-T165 PolarHBondContact OG-N 3.12Å; S163-T165 PolarHBondContact OG-O 2.9Å; T165-R167 WeakPolarHBondContact O-CG 3.38Å
166L97.9Very high89.7Confident1 Ų141.6 Ų41.61%0.00523%0.233CC..  trans-67.1135.2174.4-178.961.4000109.6V35 R40 M43 H83 A151 W153V35-L166 HydrophobicContact CG2-CB 3.9Å; V35-L166 HydrophobicContact CG2-CD2 3.78Å; V35-L166 HydrophobicContact CG2-CG 3.7Å; V35-L166 WeakPolarHBondContact CG2-O 3.4Å; V35-L166 PolarHBondContact N-O 3.27Å; V35-L166 VanDerWaalsContact N-O 3.08Å; R40-L166 HydrophobicContact CB-CD2 3.99Å; R40-L166 HydrophobicContact CG-CD2 4.47Å; M43-L166 HydrophobicContact CB-CD2 4.22Å; M43-L166 HydrophobicContact CE-CD1 4.23Å; M43-L166 HydrophobicContact CG-CD1 4.49Å; M43-L166 HydrophobicContact CG-CD2 4.07Å; H83-L166 PolarHBondContact O-N 2.86Å; A151-L166 HydrophobicContact CB-CD1 4.14Å; W153-L166 HydrophobicContact CD2-CB 4.48Å; W153-L166 HydrophobicContact CD2-CD1 3.89Å; W153-L166 HydrophobicContact CE3-CD1 3.93Å; W153-L166 HydrophobicContact CH2-CD1 3.82Å; W153-L166 HydrophobicContact CH2-CD2 4.25Å; W153-L166 HydrophobicContact CH2-CG 4.44Å; W153-L166 HydrophobicContact CZ2-CB 3.76Å; W153-L166 HydrophobicContact CZ2-CD1 3.77Å; W153-L166 HydrophobicContact CZ2-CD2 4.09Å; W153-L166 HydrophobicContact CZ2-CG 4.08Å; W153-L166 HydrophobicContact CZ3-CD1 3.89Å
167R96.9Very high90.6Very high30 Ų3048 Ų4811%0.11326%0.259CS..EExtended strand (participates in β ladder)trans-132.7162.8-179.9-54.3-169.576.293.1-4.1110.5I29 G32 N33 E34 A151 G152 S163 T165I29-R167 HydrophobicContact CB-CB 3.97Å; I29-R167 HydrophobicContact CG1-CB 3.4Å; I29-R167 HydrophobicContact CG1-CG 4.24Å; I29-R167 VanDerWaalsContact N-CD 3.32Å; G32-R167 PolarHBondContact O-NE 3.25Å; G32-R167 VanDerWaalsContact O-NE 3.1Å; N33-R167 CarbonylContact O-C 3.58Å; N33-R167 WeakPolarHBondContact O-CA 3.42Å; N33-R167 VanDerWaalsContact O-CB 3.31Å; N33-R167 WeakPolarHBondContact O-CB 3.23Å; E34-R167 VanDerWaalsContact N-CZ 3.27Å; E34-R167 VanDerWaalsContact N-NH2 3.17Å; A151-R167 CarbonylContact C-O 3.59Å; A151-R167 WeakPolarHBondContact CA-O 3.39Å; A151-R167 WeakPolarHBondContact CB-O 3.42Å; G152-R167 PolarHBondContact N-O 3.13Å; G152-R167 PolarHBondContact O-N 3.47Å; S163-R167 WeakPolarHBondContact OG-CD 3.5Å; T165-R167 WeakPolarHBondContact O-CG 3.38Å
168E97.4Very high91.7Very high30 Ų3047 Ų4714%0.1426%0.256CS..EExtended strand (participates in β ladder)trans-141140.8-179.9-179.5174.994.200111.4G32 N33 V35 R40 Q149 V150 A151G32-E168 CarbonylContact C-O 3.38Å; G32-E168 VanDerWaalsContact C-O 3.25Å; G32-E168 WeakPolarHBondContact CA-O 3.42Å; N33-E168 PolarHBondContact N-O 3.11Å; N33-E168 PolarHBondContact O-N 2.86Å; V35-E168 HydrophobicContact CG1-CB 3.43Å; V35-E168 VanDerWaalsContact CG1-CB 3.43Å; R40-E168 IonicContact CZ-OE1 3.63Å; R40-E168 IonicContact CZ-OE2 3.39Å; R40-E168 IonicContact NE-OE1 3.71Å; R40-E168 IonicContact NE-OE2 2.69Å; R40-E168 PolarHBondContact NE-OE2 2.76Å; R40-E168 VanDerWaalsContact NH2-CD 3.32Å; R40-E168 IonicContact NH2-OE1 2.68Å; R40-E168 PolarHBondContact NH2-OE1 3.3Å; R40-E168 IonicContact NH2-OE2 2.71Å; R40-E168 PolarHBondContact NH2-OE2 2.71Å; Q149-E168 HydrophobicContact CB-CG 3.92Å; Q149-E168 HydrophobicContact CG-CG 4.32Å; V150-E168 WeakPolarHBondContact O-CA 3.17Å; A151-E168 HydrophobicContact CB-CB 4.05Å; A151-E168 HydrophobicContact CB-CG 4.3Å
169V96.1Very high93Very high1 Ų144.1 Ų44.11%0.00624%0.24CC..EExtended strand (participates in β ladder)trans-121.1138.7174.8620000111.2I29 G31 Q149 V150 I171 K205I29-V169 HydrophobicContact CG2-CB 3.94Å; I29-V169 HydrophobicContact CG2-CG1 3.67Å; G31-V169 WeakPolarHBondContact O-CG2 3.2Å; Q149-V169 WeakPolarHBondContact CA-O 3.41Å; V150-V169 HydrophobicContact CG1-CG1 3.46Å; V150-V169 VanDerWaalsContact CG1-CG1 3.46Å; V150-V169 PolarHBondContact N-O 3.04Å; V150-V169 PolarHBondContact O-N 2.85Å; V169-I171 HydrophobicContact CG1-CG2 4.06Å; V169-I171 HydrophobicContact CG2-CG2 4.1Å; V169-K205 HydrophobicContact CG2-CB 3.84Å; V169-K205 HydrophobicContact CG2-CD 4.27Å; V169-K205 HydrophobicContact CG2-CG 4.09Å
170N97.1Very high94.6Very high89 Ų8939.5 Ų39.548%0.47621%0.207SC..EExtended strand (participates in β ladder)trans-83.3121.9168.5-70.3-53.4000109.7C148 Q149 K205C148-N170 WeakPolarHBondContact O-CA 3.21Å; Q149-N170 VanDerWaalsContact CG-OD1 3.23Å; Q149-N170 WeakPolarHBondContact CG-OD1 3.46Å; Q149-N170 PolarHBondContact NE2-OD1 2.87Å; N170-K205 WeakPolarHBondContact O-CD 3.31Å
171I97.9Very high95.8Very high2 Ų241 Ų411%0.0121%0.214CC..EExtended strand (participates in β ladder)trans-127.7163.3179.654.7-177.6000110.5C148 V150 V169 A198 K205 L216 Y243C148-I171 HydrophobicContact CB-CG1 4.27Å; C148-I171 PolarHBondContact N-O 2.89Å; C148-I171 PolarHBondContact O-N 2.92Å; C148-I171 VanDerWaalsContact O-O 3.07Å; V150-I171 HydrophobicContact CB-CD1 4.31Å; V150-I171 HydrophobicContact CG1-CD1 3.78Å; V169-I171 HydrophobicContact CG1-CG2 4.06Å; V169-I171 HydrophobicContact CG2-CG2 4.1Å; I171-A198 HydrophobicContact CB-CB 4.39Å; I171-A198 HydrophobicContact CD1-CB 3.61Å; I171-A198 HydrophobicContact CG1-CB 3.98Å; I171-K205 HydrophobicContact CG2-CB 4.15Å; I171-L216 HydrophobicContact CD1-CD1 3.77Å; I171-L216 HydrophobicContact CG1-CD1 4.3Å; I171-Y243 HydrophobicContact CD1-CE2 4.17Å; I171-Y243 WeakPolarHBondContact CD1-OH 3.46Å
172T98.3Very high96.8Very high56 Ų5641.4 Ų41.434%0.34421%0.214SC..EExtended strand (participates in β ladder)trans-121.1138.5-178.5-58.30000110G145 T146 I174 A198 G199G145-T172 VanDerWaalsContact CA-CG2 3.45Å; T146-T172 WeakPolarHBondContact O-CA 3.36Å; T172-I174 PolarHBondContact O-N 2.94Å; T172-A198 VanDerWaalsContact O-CA 3.27Å; T172-A198 WeakPolarHBondContact O-CA 3.03Å; T172-G199 PolarHBondContact N-O 3.3Å; T172-G199 PolarHBondContact O-N 2.86Å
173I98.8Very high97.4Very high7 Ų746.1 Ų46.14%0.03623%0.233CC..EExtended strand (participates in β ladder)trans-62125.8174.2-61-73.4000109.5V142 G145 T146 C148 V196 C197 A198 L216V142-I173 HydrophobicContact CB-CD1 4.03Å; V142-I173 HydrophobicContact CB-CG1 4.02Å; V142-I173 HydrophobicContact CG1-CD1 4.08Å; V142-I173 HydrophobicContact CG1-CG1 3.66Å; G145-I173 PolarHBondContact N-O 3.25Å; T146-I173 PolarHBondContact O-N 2.97Å; C148-I173 VanDerWaalsContact SG-CG1 3.6Å; I173-V196 HydrophobicContact CD1-CB 4.3Å; I173-V196 HydrophobicContact CD1-CG2 4.28Å; I173-C197 WeakPolarHBondContact CA-O 2.97Å; I173-A198 HydrophobicContact CD1-CB 4.13Å; I173-L216 HydrophobicContact CD1-CD2 4.26Å
174I98.6Very high97.7Very high10 Ų1046.6 Ų46.65%0.05124%0.235CC..EExtended strand (participates in β ladder)trans-95.9139.6175.7-65.9168000108.3T172 R176 I178 C197 L201 P240T172-I174 PolarHBondContact O-N 2.94Å; I174-R176 PolarHBondContact O-N 2.91Å; I174-I178 HydrophobicContact CG2-CB 3.99Å; I174-I178 HydrophobicContact CG2-CG2 3.82Å; I174-C197 HydrophobicContact CB-CB 4.14Å; I174-C197 PolarHBondContact N-O 3.33Å; I174-L201 HydrophobicContact CD1-CD2 4.2Å; I174-L201 HydrophobicContact CG1-CD2 4.12Å; I174-L201 HydrophobicContact CG2-CD2 4.33Å; I174-P240 HydrophobicContact CD1-CB 3.52Å; I174-P240 HydrophobicContact CD1-CG 3.81Å
175D98.5Very high97.8Very high56 Ų5644.6 Ų44.630%0.29922%0.223SC..PPolyproline II helixtrans-57.7132.9177.8-173.5-77.1000110.8P144 K177 I178 C179P144-D175 HydrophobicContact CB-CB 3.99Å; P144-D175 HydrophobicContact CG-CB 3.87Å; P144-D175 WeakPolarHBondContact CG-OD2 3.12Å; D175-K177 PolarHBondContact O-N 3Å; D175-K177 WeakPolarHBondContact OD1-CA 3.44Å; D175-K177 WeakPolarHBondContact OD1-CB 3.28Å; D175-K177 WeakPolarHBondContact OD1-CG 3.42Å; D175-K177 PolarHBondContact OD1-N 2.81Å; D175-I178 HydrophobicContact CB-CB 4.36Å; D175-I178 HydrophobicContact CB-CD1 3.9Å; D175-I178 HydrophobicContact CB-CG1 4.02Å; D175-I178 WeakPolarHBondContact O-CA 3.49Å; D175-I178 WeakPolarHBondContact O-CB 3.09Å; D175-I178 PolarHBondContact O-N 2.82Å; D175-C179 PolarHBondContact O-N 2.82Å
176R98.5Very high97.9Very high33 Ų3347.8 Ų47.813%0.12524%0.239CC..Hα-helixtrans-61.6-29.1-175.7-168.2177.1-70.4103.81.7112.8D141 I174 C179 N180 I191 G192 M193 M195D141-R176 VanDerWaalsContact CG-NH2 3.34Å; D141-R176 IonicContact OD1-CZ 3.85Å; D141-R176 IonicContact OD1-NH2 3.25Å; D141-R176 PolarHBondContact OD1-NH2 2.83Å; D141-R176 IonicContact OD2-CZ 2.76Å; D141-R176 IonicContact OD2-NH1 3.75Å; D141-R176 PolarHBondContact OD2-NH1 3.26Å; D141-R176 IonicContact OD2-NH2 3.61Å; D141-R176 PolarHBondContact OD2-NH2 2.92Å; D141-R176 VanDerWaalsContact OD2-NH2 3.08Å; I174-R176 PolarHBondContact O-N 2.91Å; R176-C179 PolarHBondContact O-N 2.7Å; R176-N180 PolarHBondContact O-N 2.87Å; R176-N180 PolarHBondContact O-ND2 2.93Å; R176-I191 WeakPolarHBondContact CD-O 2.97Å; R176-I191 HydrophobicContact CG-CB 4.39Å; R176-I191 HydrophobicContact CG-CG2 4.12Å; R176-I191 VanDerWaalsContact CG-O 3.28Å; R176-I191 WeakPolarHBondContact CG-O 3.39Å; R176-G192 VanDerWaalsContact CD-O 3.3Å; R176-G192 WeakPolarHBondContact CD-O 3.48Å; R176-G192 PolarHBondContact NE-O 3.01Å; R176-M193 VanDerWaalsContact CD-CE 3.46Å; R176-M195 VanDerWaalsContact CZ-O 3.29Å; R176-M195 PolarHBondContact NE-O 3.29Å; R176-M195 PolarHBondContact NH2-O 3.36Å
177K98.4Very high97.9Very high173 Ų17354 Ų5475%0.75227%0.266SS*.Hα-helixtrans-69-41.4173.6-59.7178.4178.8178.30111.1D175 C179 N180 D181D175-K177 PolarHBondContact O-N 3Å; D175-K177 WeakPolarHBondContact OD1-CA 3.44Å; D175-K177 WeakPolarHBondContact OD1-CB 3.28Å; D175-K177 WeakPolarHBondContact OD1-CG 3.42Å; D175-K177 PolarHBondContact OD1-N 2.81Å; K177-C179 VanDerWaalsContact C-N 3.29Å; K177-N180 PolarHBondContact O-N 2.85Å; K177-D181 PolarHBondContact O-N 3.42Å
178I98.1Very high97.8Very high65 Ų6559 Ų5933%0.33330%0.295SS..Hα-helixtrans-60.2-46.1172.9-64.4175000109.1I174 D175 N180 D181 H184I174-I178 HydrophobicContact CG2-CB 3.99Å; I174-I178 HydrophobicContact CG2-CG2 3.82Å; D175-I178 HydrophobicContact CB-CB 4.36Å; D175-I178 HydrophobicContact CB-CD1 3.9Å; D175-I178 HydrophobicContact CB-CG1 4.02Å; D175-I178 WeakPolarHBondContact O-CA 3.49Å; D175-I178 WeakPolarHBondContact O-CB 3.09Å; D175-I178 PolarHBondContact O-N 2.82Å; I178-N180 PolarHBondContact O-N 3.16Å; I178-N180 VanDerWaalsContact O-N 3.15Å; I178-D181 WeakPolarHBondContact O-CB 3.27Å; I178-D181 PolarHBondContact O-N 3.01Å; I178-H184 WeakPolarHBondContact CG2-CE1 3.48Å; I178-H184 PolarHBondContact O-ND1 2.76Å; I178-H184 VanDerWaalsContact O-ND1 3.1Å
179C98.1Very high97.8Very high0 Ų058.9 Ų58.90%030%0.297CS..Hα-helixtrans-60.9-28.9-178.5-136.40000113.9D175 R176 K177 H184 Y185 I191 C197D175-C179 PolarHBondContact O-N 2.82Å; R176-C179 PolarHBondContact O-N 2.7Å; K177-C179 VanDerWaalsContact C-N 3.29Å; C179-H184 VanDerWaalsContact O-CB 3.24Å; C179-H184 WeakPolarHBondContact O-CB 3.44Å; C179-Y185 WeakPolarHBondContact O-CB 3.27Å; C179-Y185 WeakPolarHBondContact O-CD2 3.4Å; C179-Y185 PolarHBondContact O-N 3.25Å; C179-I191 HydrophobicContact CB-CG1 4.29Å; C179-C197 HydrophobicContact CB-CB 3.85Å; C179-C197 WeakPolarHBondContact CB-SG 3.49Å; C179-C197 WeakPolarHBondContact SG-CB 3.47Å; C179-C197 CovalentContact SG-SG 2Å; C179-C197 PolarHBondContact SG-SG 3.41Å
180N98.6Very high97.9Very high12 Ų1262.7 Ų62.76%0.06432%0.32CS..THydrogen-bonded Turntrans-91.6-1.4175.6-75.7-73.1000114.1R176 K177 I178 N186 F187 I191R176-N180 PolarHBondContact O-N 2.87Å; R176-N180 PolarHBondContact O-ND2 2.93Å; K177-N180 PolarHBondContact O-N 2.85Å; I178-N180 PolarHBondContact O-N 3.16Å; I178-N180 VanDerWaalsContact O-N 3.15Å; N180-N186 WeakPolarHBondContact O-CA 3.48Å; N180-F187 HydrophobicContact CB-CD1 4.12Å; N180-F187 HydrophobicContact CB-CE1 3.89Å; N180-F187 HydrophobicContact CB-CE2 4.36Å; N180-F187 HydrophobicContact CB-CG 4.46Å; N180-F187 HydrophobicContact CB-CZ 4.02Å; N180-F187 VanDerWaalsContact O-CD2 3.28Å; N180-F187 WeakPolarHBondContact O-CD2 3.27Å; N180-F187 VanDerWaalsContact O-CE2 3.27Å; N180-F187 WeakPolarHBondContact O-CE2 3.42Å; N180-F187 PolarHBondContact O-N 3.14Å; N180-I191 PolarHBondContact ND2-O 3.09Å; N180-I191 PolarHBondContact OD1-N 2.9Å
181D98.1Very high98Very high43 Ų4358.5 Ų58.523%0.2330%0.298CS..SBendtrans-70.4168.5-176.386.314.6000112.5K177 I178 K183 H184 N186K177-D181 PolarHBondContact O-N 3.42Å; I178-D181 WeakPolarHBondContact O-CB 3.27Å; I178-D181 PolarHBondContact O-N 3.01Å; D181-K183 PolarHBondContact O-N 3.14Å; D181-K183 VanDerWaalsContact O-N 3.15Å; D181-K183 WeakPolarHBondContact OD1-CA 3.45Å; D181-K183 WeakPolarHBondContact OD1-CB 3.25Å; D181-K183 PolarHBondContact OD1-N 3.36Å; D181-H184 VanDerWaalsContact CG-ND1 3.26Å; D181-H184 PolarHBondContact O-N 2.84Å; D181-H184 VanDerWaalsContact O-N 3.08Å; D181-H184 IonicContact OD1-CE1 3.4Å; D181-H184 IonicContact OD1-CG 3.35Å; D181-H184 PolarHBondContact OD1-N 3.32Å; D181-H184 IonicContact OD1-ND1 2.77Å; D181-H184 PolarHBondContact OD1-ND1 3.47Å; D181-H184 IonicContact OD2-CE1 3.64Å; D181-H184 IonicContact OD2-ND1 3.08Å; D181-H184 PolarHBondContact OD2-ND1 2.68Å; D181-N186 VanDerWaalsContact O-CA 3.27Å; D181-N186 WeakPolarHBondContact O-CA 3.28Å; D181-N186 PolarHBondContact O-N 2.04Å
182P98.1Very high98Very high105 Ų10559.2 Ų59.268%0.68231%0.306SS*.THydrogen-bonded Turntrans-62.1-19.4-179.1-26.536.6000116
183K97Very high97.9Very high167 Ų16762.8 Ų62.873%0.72632%0.32SS*.THydrogen-bonded Turntrans-87-18.4178.1-61.9-179.2-179.9178.70111.9D181 G238D181-K183 PolarHBondContact O-N 3.14Å; D181-K183 VanDerWaalsContact O-N 3.15Å; D181-K183 WeakPolarHBondContact OD1-CA 3.45Å; D181-K183 WeakPolarHBondContact OD1-CB 3.25Å; D181-K183 PolarHBondContact OD1-N 3.36Å; K183-G238 WeakPolarHBondContact O-CA 3.19Å
184H97.7Very high97.9Very high20 Ų2064 Ų649%0.09333%0.327CS..THydrogen-bonded Turntrans-108.6-122.3-179-59.380.9000111.5I178 C179 D181 N186 R230 P237 G238I178-H184 WeakPolarHBondContact CG2-CE1 3.48Å; I178-H184 PolarHBondContact O-ND1 2.76Å; I178-H184 VanDerWaalsContact O-ND1 3.1Å; C179-H184 VanDerWaalsContact O-CB 3.24Å; C179-H184 WeakPolarHBondContact O-CB 3.44Å; D181-H184 VanDerWaalsContact CG-ND1 3.26Å; D181-H184 PolarHBondContact O-N 2.84Å; D181-H184 VanDerWaalsContact O-N 3.08Å; D181-H184 IonicContact OD1-CE1 3.4Å; D181-H184 IonicContact OD1-CG 3.35Å; D181-H184 PolarHBondContact OD1-N 3.32Å; D181-H184 IonicContact OD1-ND1 2.77Å; D181-H184 PolarHBondContact OD1-ND1 3.47Å; D181-H184 IonicContact OD2-CE1 3.64Å; D181-H184 IonicContact OD2-ND1 3.08Å; D181-H184 PolarHBondContact OD2-ND1 2.68Å; H184-N186 VanDerWaalsContact C-N 3.29Å; H184-N186 PolarHBondContact O-N 2.89Å; H184-R230 PolarHBondContact O-NH2 3.38Å; H184-P237 PolarHBondContact CD2-O 2.04Å; H184-P237 PolarHBondContact NE2-O 2.83Å; H184-G238 CarbonylContact C-O 3.47Å; H184-G238 VanDerWaalsContact CA-O 3.22Å; H184-G238 WeakPolarHBondContact CA-O 3.33Å
185Y97.6Very high97.9Very high12 Ų1263.5 Ų63.55%0.04732%0.324CS..THydrogen-bonded Turntrans-75.6-15.7-177.8-72-76.4000113.7C179 F187 N188 I191 F228 R230 P240 V242C179-Y185 WeakPolarHBondContact O-CB 3.27Å; C179-Y185 WeakPolarHBondContact O-CD2 3.4Å; C179-Y185 PolarHBondContact O-N 3.25Å; Y185-F187 PolarHBondContact O-N 2.89Å; Y185-N188 CarbonylContact O-C 3.46Å; Y185-N188 WeakPolarHBondContact O-CA 3.43Å; Y185-N188 PolarHBondContact O-N 3.11Å; Y185-N188 VanDerWaalsContact O-O 3.11Å; Y185-I191 HydrophobicContact CD2-CD1 3.87Å; Y185-I191 HydrophobicContact CD2-CG1 3.86Å; Y185-I191 HydrophobicContact CE2-CD1 4.24Å; Y185-I191 HydrophobicContact CG-CD1 4.1Å; Y185-I191 HydrophobicContact CG-CG1 4.28Å; Y185-F228 HydrophobicContact CD1-CE2 4.38Å; Y185-F228 HydrophobicContact CE1-CD2 4.35Å; Y185-F228 AromaticContact CE1-CE2 3.7Å; Y185-F228 HydrophobicContact CE1-CE2 3.7Å; Y185-F228 AromaticContact CZ-CE2 3.93Å; Y185-R230 HydrophobicContact CE1-CG 4.32Å; Y185-P240 HydrophobicContact CE2-CG 4.37Å; Y185-P240 PolarHBondContact OH-O 3.17Å; Y185-V242 HydrophobicContact CD2-CG2 4.5Å; Y185-V242 HydrophobicContact CE2-CG2 3.59Å; Y185-V242 WeakPolarHBondContact OH-CG2 3.3Å
186N98.2Very high97.9Very high91 Ų9161 Ų6149%0.48731%0.311SS..THydrogen-bonded Turntrans48.147.3178.5-170.635.9000112.8N180 D181 H184 N188N180-N186 WeakPolarHBondContact O-CA 3.48Å; D181-N186 VanDerWaalsContact O-CA 3.27Å; D181-N186 WeakPolarHBondContact O-CA 3.28Å; D181-N186 PolarHBondContact O-N 2.04Å; H184-N186 VanDerWaalsContact C-N 3.29Å; H184-N186 PolarHBondContact O-N 2.89Å; N186-N188 PolarHBondContact O-N 2.82Å; N186-N188 VanDerWaalsContact O-N 3.07Å
187F97.6Very high97.9Very high131 Ų13159.5 Ų59.558%0.57531%0.306SS*.THydrogen-bonded Turntrans5620.8-175.7-59.6-88.5000115N180 Y185 P189 V190N180-F187 HydrophobicContact CB-CD1 4.12Å; N180-F187 HydrophobicContact CB-CE1 3.89Å; N180-F187 HydrophobicContact CB-CE2 4.36Å; N180-F187 HydrophobicContact CB-CG 4.46Å; N180-F187 HydrophobicContact CB-CZ 4.02Å; N180-F187 VanDerWaalsContact O-CD2 3.28Å; N180-F187 WeakPolarHBondContact O-CD2 3.27Å; N180-F187 VanDerWaalsContact O-CE2 3.27Å; N180-F187 WeakPolarHBondContact O-CE2 3.42Å; N180-F187 PolarHBondContact O-N 3.14Å; Y185-F187 PolarHBondContact O-N 2.89Å; F187-P189 VanDerWaalsContact C-C 3.45Å; F187-P189 CarbonylContact C-O 3.53Å; F187-P189 CarbonylContact O-C 3.6Å; F187-V190 HydrophobicContact CB-CG2 4.06Å; F187-V190 HydrophobicContact CD1-CG1 4.46Å; F187-V190 HydrophobicContact CD1-CG2 4.32Å; F187-V190 VanDerWaalsContact O-CG2 3.29Å; F187-V190 WeakPolarHBondContact O-CG2 3.38Å; F187-V190 PolarHBondContact O-N 3.35Å
188N96.1Very high97.9Very high135 Ų13551.3 Ų51.372%0.72227%0.27SS*.SBendtrans-139.393.8179.3-171.617.3000112.9Y185 N186Y185-N188 CarbonylContact O-C 3.46Å; Y185-N188 WeakPolarHBondContact O-CA 3.43Å; Y185-N188 PolarHBondContact O-N 3.11Å; Y185-N188 VanDerWaalsContact O-O 3.11Å; N186-N188 PolarHBondContact O-N 2.82Å; N186-N188 VanDerWaalsContact O-N 3.07Å
189P96.6Very high97.9Very high29 Ų2948.3 Ų48.319%0.18826%0.255CS..SBendcis-70.3164.1-831.4-36.3000112F187 I191 F228F187-P189 VanDerWaalsContact C-C 3.45Å; F187-P189 CarbonylContact C-O 3.53Å; F187-P189 CarbonylContact O-C 3.6Å; P189-I191 PolarHBondContact O-N 2.93Å; P189-F228 HydrophobicContact CG-CE1 4.49Å; P189-F228 HydrophobicContact CG-CE2 3.59Å; P189-F228 HydrophobicContact CG-CZ 3.48Å; P189-F228 VanDerWaalsContact CG-CZ 3.48Å
190V98.3Very high97.6Very high80 Ų8049.8 Ų49.849%0.48527%0.265SS..  trans-73.4125.6172.2-179.40000109.4F187 G192F187-V190 HydrophobicContact CB-CG2 4.06Å; F187-V190 HydrophobicContact CD1-CG1 4.46Å; F187-V190 HydrophobicContact CD1-CG2 4.32Å; F187-V190 VanDerWaalsContact O-CG2 3.29Å; F187-V190 WeakPolarHBondContact O-CG2 3.38Å; F187-V190 PolarHBondContact O-N 3.35Å; V190-G192 PolarHBondContact O-N 3.05Å
191I98.5Very high97.2Very high2 Ų254.9 Ų54.91%0.0129%0.292CS..  trans-85.297.8173.3-46.7-52.6000108.8R176 C179 N180 Y185 P189 M195 F228 V242R176-I191 WeakPolarHBondContact CD-O 2.97Å; R176-I191 HydrophobicContact CG-CB 4.39Å; R176-I191 HydrophobicContact CG-CG2 4.12Å; R176-I191 VanDerWaalsContact CG-O 3.28Å; R176-I191 WeakPolarHBondContact CG-O 3.39Å; C179-I191 HydrophobicContact CB-CG1 4.29Å; N180-I191 PolarHBondContact ND2-O 3.09Å; N180-I191 PolarHBondContact OD1-N 2.9Å; Y185-I191 HydrophobicContact CD2-CD1 3.87Å; Y185-I191 HydrophobicContact CD2-CG1 3.86Å; Y185-I191 HydrophobicContact CE2-CD1 4.24Å; Y185-I191 HydrophobicContact CG-CD1 4.1Å; Y185-I191 HydrophobicContact CG-CG1 4.28Å; P189-I191 PolarHBondContact O-N 2.93Å; I191-M195 HydrophobicContact CG2-CB 3.76Å; I191-F228 HydrophobicContact CD1-CE2 4.43Å; I191-F228 HydrophobicContact CD1-CZ 3.78Å; I191-V242 HydrophobicContact CD1-CG1 4.24Å; I191-V242 HydrophobicContact CD1-CG2 3.8Å
192G97.6Very high96.8Very high17 Ų1764.2 Ų64.218%0.17532%0.324CS..  trans-80.9-179.9-176.400000114.9R176 V190 N194 M195R176-G192 VanDerWaalsContact CD-O 3.3Å; R176-G192 WeakPolarHBondContact CD-O 3.48Å; R176-G192 PolarHBondContact NE-O 3.01Å; V190-G192 PolarHBondContact O-N 3.05Å; G192-N194 PolarHBondContact O-N 3.07Å; G192-N194 VanDerWaalsContact O-N 3.15Å; G192-M195 PolarHBondContact O-N 2.93Å; G192-M195 VanDerWaalsContact O-N 3.08Å; G192-M195 VanDerWaalsContact O-O 3.14Å
193M97.9Very high96.4Very high131 Ų13159.7 Ų59.765%0.64530%0.296SS*.THydrogen-bonded Turntrans-65.4-15.5-179.4-66.7-61.8117.700114.2R176 M195 L245R176-M193 VanDerWaalsContact CD-CE 3.46Å; M193-M195 VanDerWaalsContact C-N 3.34Å; M193-L245 WeakPolarHBondContact O-CD2 3.22Å
194N98.1Very high96Very high32 Ų3253.7 Ų53.717%0.17128%0.282CS..THydrogen-bonded Turntrans-93.86.4177.7-74.7-42.8000112.8E112 G192 L245 S247 K249 Y250E112-N194 VanDerWaalsContact OE1-CB 3.31Å; E112-N194 WeakPolarHBondContact OE1-CB 3.19Å; E112-N194 PolarHBondContact OE1-ND2 3.13Å; G192-N194 PolarHBondContact O-N 3.07Å; G192-N194 VanDerWaalsContact O-N 3.15Å; N194-L245 WeakPolarHBondContact O-CB 3.29Å; N194-L245 PolarHBondContact O-N 2.9Å; N194-S247 PolarHBondContact OD1-OG 3.41Å; N194-S247 VanDerWaalsContact OD1-OG 3.12Å; N194-K249 PolarHBondContact ND2-NZ 3.1Å; N194-Y250 HydrophobicContact CB-CE2 3.69Å; N194-Y250 WeakPolarHBondContact CB-OH 3.21Å
195M98.8Very high95.7Very high0 Ų057 Ų570%030%0.296CS..EExtended strand (participates in β ladder)trans-128.3151.6178.5-62.7178.1-172.800110H111 E112 R176 I191 G192 M193 F228 V242 Y243 I244H111-M195 VanDerWaalsContact C-CE 3.5Å; H111-M195 WeakPolarHBondContact O-CE 3.31Å; E112-M195 VanDerWaalsContact CA-CE 3.42Å; E112-M195 HydrophobicContact CB-CE 4.12Å; R176-M195 VanDerWaalsContact CZ-O 3.29Å; R176-M195 PolarHBondContact NE-O 3.29Å; R176-M195 PolarHBondContact NH2-O 3.36Å; I191-M195 HydrophobicContact CG2-CB 3.76Å; G192-M195 PolarHBondContact O-N 2.93Å; G192-M195 VanDerWaalsContact O-N 3.08Å; G192-M195 VanDerWaalsContact O-O 3.14Å; M193-M195 VanDerWaalsContact C-N 3.34Å; M195-F228 HydrophobicContact SD-CE1 4.24Å; M195-V242 HydrophobicContact CB-CG1 3.97Å; M195-V242 HydrophobicContact CG-CG1 4.23Å; M195-V242 HydrophobicContact SD-CG1 3.91Å; M195-Y243 CarbonylContact C-O 3.46Å; M195-Y243 VanDerWaalsContact CA-O 3.29Å; M195-Y243 WeakPolarHBondContact CA-O 3.28Å; M195-I244 HydrophobicContact CE-CD1 4.39Å; M195-I244 HydrophobicContact CG-CD1 4.17Å
196V98.8Very high95.4Very high4 Ų456.5 Ų56.52%0.02429%0.294CS..EExtended strand (participates in β ladder)trans-126.7148168.8-66.60000109.6D141 I173 L216 V242 Y243 L245D141-V196 WeakPolarHBondContact OD1-CG1 3.13Å; I173-V196 HydrophobicContact CD1-CB 4.3Å; I173-V196 HydrophobicContact CD1-CG2 4.28Å; V196-L216 HydrophobicContact CG2-CD2 3.88Å; V196-V242 WeakPolarHBondContact O-CA 3.38Å; V196-Y243 PolarHBondContact N-O 3.44Å; V196-Y243 PolarHBondContact O-N 3.31Å; V196-L245 HydrophobicContact CG1-CB 4.32Å; V196-L245 HydrophobicContact CG1-CD1 3.95Å
197C98.6Very high95Very high1 Ų152.5 Ų52.51%0.00727%0.273CS..EExtended strand (participates in β ladder)trans-101138.6169.9-66.50000109.9I173 I174 C179 P240 G241I173-C197 WeakPolarHBondContact CA-O 2.97Å; I174-C197 HydrophobicContact CB-CB 4.14Å; I174-C197 PolarHBondContact N-O 3.33Å; C179-C197 HydrophobicContact CB-CB 3.85Å; C179-C197 WeakPolarHBondContact CB-SG 3.49Å; C179-C197 WeakPolarHBondContact SG-CB 3.47Å; C179-C197 CovalentContact SG-SG 2Å; C179-C197 PolarHBondContact SG-SG 3.41Å; C197-P240 HydrophobicContact CB-CG 4.23Å; C197-G241 WeakPolarHBondContact CA-O 3.17Å
198A98.4Very high94.8Very high0 Ų046.8 Ų46.80%025%0.249CC..EExtended strand (participates in β ladder)trans-143.8141.7173.700000110.9I171 T172 I173 L216 G241 Y243I171-A198 HydrophobicContact CB-CB 4.39Å; I171-A198 HydrophobicContact CD1-CB 3.61Å; I171-A198 HydrophobicContact CG1-CB 3.98Å; T172-A198 VanDerWaalsContact O-CA 3.27Å; T172-A198 WeakPolarHBondContact O-CA 3.03Å; I173-A198 HydrophobicContact CD1-CB 4.13Å; A198-L216 HydrophobicContact CB-CD1 4.49Å; A198-G241 PolarHBondContact N-O 3.44Å; A198-G241 PolarHBondContact O-N 2.96Å; A198-Y243 HydrophobicContact CB-CD2 4.15Å; A198-Y243 HydrophobicContact CB-CE2 3.72Å
199G96.4Very high94.5Very high2 Ų243.4 Ų43.42%0.02123%0.231CC..EExtended strand (participates in β ladder)trans173.8-146.3179.500000110.7T172 K205T172-G199 PolarHBondContact N-O 3.3Å; T172-G199 PolarHBondContact O-N 2.86Å; G199-K205 WeakPolarHBondContact CA-O 3.17Å
200S93.6Very high94.3Very high32 Ų3242.4 Ų42.422%0.22423%0.226CC..  trans-121.2132170.6163.90000109.2R202 G203S200-R202 PolarHBondContact O-N 3.19Å; S200-R202 VanDerWaalsContact O-N 3.14Å; S200-R202 PolarHBondContact OG-N 3.37Å; S200-R202 VanDerWaalsContact OG-N 3.16Å; S200-G203 WeakPolarHBondContact CB-O 3.1Å; S200-G203 WeakPolarHBondContact O-CA 2.95Å; S200-G203 PolarHBondContact O-N 3.07Å; S200-G203 PolarHBondContact OG-N 3.12Å; S200-G203 PolarHBondContact OG-O 3.22Å
201L88.8Confident94.3Very high118 Ų11838.6 Ų38.662%0.61820%0.203SC*.THydrogen-bonded Turntrans-61.4-20173.2-69.1175.8000112.7I174I174-L201 HydrophobicContact CD1-CD2 4.2Å; I174-L201 HydrophobicContact CG1-CD2 4.12Å; I174-L201 HydrophobicContact CG2-CD2 4.33Å
202R90.7Very high94.3Very high240 Ų24039.4 Ų39.491%0.90621%0.209SC*.THydrogen-bonded Turntrans-92.3-0.8174.2-62-177.7-177.91790.6112.8S200S200-R202 PolarHBondContact O-N 3.19Å; S200-R202 VanDerWaalsContact O-N 3.14Å; S200-R202 PolarHBondContact OG-N 3.37Å; S200-R202 VanDerWaalsContact OG-N 3.16Å
203G90.3Very high94.3Very high10 Ų1038.6 Ų38.610%0.10320%0.2CC..SBendtrans73.2-168.6-169.800000112.6S200 K205 G235S200-G203 WeakPolarHBondContact CB-O 3.1Å; S200-G203 WeakPolarHBondContact O-CA 2.95Å; S200-G203 PolarHBondContact O-N 3.07Å; S200-G203 PolarHBondContact OG-N 3.12Å; S200-G203 PolarHBondContact OG-O 3.22Å; G203-K205 PolarHBondContact O-N 2.78Å; G203-G235 CarbonylContact C-O 3.56Å; G203-G235 WeakPolarHBondContact CA-O 3.05Å
204G87.8Confident94.4Very high40 Ų4032.3 Ų32.341%0.41217%0.17SC..SBendtrans73.24.2175.100000115.2I30 G31 G235I30-G204 CarbonylContact C-O 3.59Å; G31-G204 WeakPolarHBondContact CA-O 3.34Å; G31-G204 PolarHBondContact N-O 2.77Å; G204-G235 PolarHBondContact N-O 3.08Å
205K90.2Very high94.4Very high90 Ų9030.9 Ų30.939%0.39116%0.162SC..  trans-137.6111.6175.7-64.6-169175.7-172.60111.3I30 V169 N170 I171 G199 G203I30-K205 WeakPolarHBondContact O-CA 3.45Å; V169-K205 HydrophobicContact CG2-CB 3.84Å; V169-K205 HydrophobicContact CG2-CD 4.27Å; V169-K205 HydrophobicContact CG2-CG 4.09Å; N170-K205 WeakPolarHBondContact O-CD 3.31Å; I171-K205 HydrophobicContact CG2-CB 4.15Å; G199-K205 WeakPolarHBondContact CA-O 3.17Å; G203-K205 PolarHBondContact O-N 2.78Å
206D92.3Very high94.4Very high2 Ų230.9 Ų30.91%0.01116%0.162CC..  trans-163.8160.8-175.3-157.13.5000113.1I29 I30 G235 G241I29-D206 WeakPolarHBondContact CG2-O 3.27Å; I30-D206 PolarHBondContact O-N 2.77Å; I30-D206 VanDerWaalsContact O-N 3.09Å; D206-G235 VanDerWaalsContact CB-N 3.3Å; D206-G235 PolarHBondContact OD2-N 2.99Å; D206-G241 VanDerWaalsContact OD1-CA 3.31Å; D206-G241 WeakPolarHBondContact OD1-CA 3.36Å; D206-G241 PolarHBondContact OD1-N 2.97Å; D206-G241 VanDerWaalsContact OD1-N 3.14Å
207S90.9Very high94.4Very high7 Ų731.3 Ų31.35%0.04916%0.164CC..  trans-73.3159.4157.457.80000110.5Y243S207-Y243 PolarHBondContact OG-OH 2.85Å
208C92.6Very high94.4Very high10 Ų1031.4 Ų31.47%0.06817%0.165CC..  trans-143.1-174.7177.8-159.40000113.8R155 G210 D211 C234R155-C208 HydrophobicContact CB-CB 4.33Å; C208-G210 PolarHBondContact O-N 3.08Å; C208-G210 VanDerWaalsContact O-N 3.11Å; C208-D211 PolarHBondContact N-OD2 2.89Å; C208-D211 WeakPolarHBondContact O-CB 3.42Å; C208-D211 PolarHBondContact O-N 2.86Å; C208-C234 WeakPolarHBondContact CA-SG 3.42Å; C208-C234 HydrophobicContact CB-CB 3.58Å; C208-C234 WeakPolarHBondContact CB-SG 3.24Å; C208-C234 WeakPolarHBondContact SG-CB 3.43Å; C208-C234 CovalentContact SG-SG 2.04Å; C208-C234 PolarHBondContact SG-SG 3.15Å
209D90.3Very high94.3Very high64 Ų6437.6 Ų37.634%0.34220%0.198SC..THydrogen-bonded Turntrans-47.7118.5176.2-70.7-16.6000110.6G154 R155G154-D209 CarbonylContact C-O 3.43Å; G154-D209 WeakPolarHBondContact CA-O 3.01Å; R155-D209 HydrophobicContact CG-CB 4.21Å; R155-D209 IonicContact CZ-OD2 3.34Å; R155-D209 PolarHBondContact N-O 3.28Å; R155-D209 IonicContact NH1-OD2 3.62Å; R155-D209 PolarHBondContact NH1-OD2 3.36Å; R155-D209 IonicContact NH2-OD2 2.74Å
210G92.7Very high94.2Very high9 Ų940.2 Ų40.29%0.09323%0.225CC..THydrogen-bonded Turntrans106.4-17.4-176.200000114.8I53 C54 C208I53-G210 WeakPolarHBondContact O-CA 3.22Å; C54-G210 CarbonylContact C-O 3.59Å; C54-G210 WeakPolarHBondContact CA-O 3.46Å; C208-G210 PolarHBondContact O-N 3.08Å; C208-G210 VanDerWaalsContact O-N 3.11Å
211D96.9Very high94.4Very high0 Ų041.2 Ų41.20%023%0.229CC..  trans-88.9-5.5176.1-59.2-42000113.4I29 G152 W153 G154 C208 G213 S214 T226I29-D211 VanDerWaalsContact CD1-OD1 3.25Å; I29-D211 WeakPolarHBondContact CD1-OD1 3.37Å; I29-D211 WeakPolarHBondContact CD1-OD2 3.43Å; G152-D211 VanDerWaalsContact CA-OD1 3.24Å; G152-D211 WeakPolarHBondContact CA-OD1 3.44Å; W153-D211 PolarHBondContact N-OD1 2.92Å; G154-D211 VanDerWaalsContact CA-OD1 3.28Å; G154-D211 WeakPolarHBondContact CA-OD1 3.29Å; G154-D211 PolarHBondContact N-OD1 3Å; C208-D211 PolarHBondContact N-OD2 2.89Å; C208-D211 WeakPolarHBondContact O-CB 3.42Å; C208-D211 PolarHBondContact O-N 2.86Å; D211-G213 PolarHBondContact O-N 3.39Å; D211-S214 WeakPolarHBondContact O-CB 3.22Å; D211-S214 PolarHBondContact O-N 2.8Å; D211-T226 HydrophobicContact CB-CG2 4.44Å; D211-T226 WeakPolarHBondContact O-CB 3.47Å
212S98.1Very high94.9Very high18 Ų1835.6 Ų35.613%0.12620%0.2CC..THydrogen-bonded Turntrans-48.1131.9174.7-67.60000111.7C54 A55 H69 S214C54-S212 WeakPolarHBondContact CB-O 3.17Å; A55-S212 PolarHBondContact N-O 2.79Å; H69-S212 VanDerWaalsContact CE1-CB 3.47Å; H69-S212 WeakPolarHBondContact CE1-CB 3.29Å; H69-S212 PolarHBondContact CE1-OG 2.89Å; H69-S212 WeakPolarHBondContact NE2-CB 3.49Å; H69-S212 PolarHBondContact NE2-OG 3.42Å; S212-S214 VanDerWaalsContact C-N 3.3Å
213G98.8Very high95.3Very high0 Ų026.6 Ų26.60%017%0.166CC..THydrogen-bonded Turntrans84.8-7.7-175.100000115.3A55 G56 D211 T226A55-G213 CarbonylContact O-C 3.16Å; A55-G213 WeakPolarHBondContact O-CA 3.43Å; G56-G213 WeakPolarHBondContact CA-O 3.31Å; D211-G213 PolarHBondContact O-N 3.39Å; G213-T226 PolarHBondContact N-O 2.95Å
214S98.8Very high95.7Very high0 Ų026.1 Ų26.10%016%0.161CC..  trans-63144.9177.2178.20000112.5V150 A151 D211 S212 V225 T226V150-S214 WeakPolarHBondContact CG2-OG 3.4Å; A151-S214 WeakPolarHBondContact O-CB 3.47Å; A151-S214 PolarHBondContact O-OG 2Å; D211-S214 WeakPolarHBondContact O-CB 3.22Å; D211-S214 PolarHBondContact O-N 2.8Å; S212-S214 VanDerWaalsContact C-N 3.3Å; S214-V225 WeakPolarHBondContact O-CA 3.32Å; S214-T226 PolarHBondContact O-N 2.75Å; S214-T226 PolarHBondContact O-OG1 2.98Å; S214-T226 VanDerWaalsContact O-OG1 3.13Å
215P98.9Very high96.2Very high2 Ų224.2 Ų24.21%0.01314%0.141CC..EExtended strand (participates in β ladder)trans-72.7127.117330.1-35.9000113.1Y42 M43 A57 L133 L217 F222Y42-P215 HydrophobicContact CD2-CG 4.11Å; Y42-P215 HydrophobicContact CE2-CG 3.82Å; M43-P215 HydrophobicContact SD-CG 3.67Å; A57-P215 HydrophobicContact CB-CB 4.11Å; A57-P215 HydrophobicContact CB-CG 4.06Å; L133-P215 HydrophobicContact CD2-CB 3.64Å; L133-P215 HydrophobicContact CD2-CG 4.04Å; P215-L217 HydrophobicContact CB-CD2 4.16Å; P215-F222 HydrophobicContact CB-CD2 3.7Å; P215-F222 HydrophobicContact CB-CE1 4.43Å; P215-F222 HydrophobicContact CB-CE2 3.32Å; P215-F222 HydrophobicContact CB-CG 4.43Å; P215-F222 HydrophobicContact CB-CZ 3.72Å
216L98.9Very high96.6Very high0 Ų020.1 Ų20.10%012%0.124CC..EExtended strand (participates in β ladder)trans-81.9114.7163.5-179.469.8000109.6C148 I171 I173 V196 A198 R223 G224 Y243C148-L216 HydrophobicContact CB-CD1 3.64Å; C148-L216 HydrophobicContact CB-CG 4.24Å; I171-L216 HydrophobicContact CD1-CD1 3.77Å; I171-L216 HydrophobicContact CG1-CD1 4.3Å; I173-L216 HydrophobicContact CD1-CD2 4.26Å; V196-L216 HydrophobicContact CG2-CD2 3.88Å; A198-L216 HydrophobicContact CB-CD1 4.49Å; L216-R223 PolarHBondContact O-N 3.25Å; L216-G224 WeakPolarHBondContact CB-O 3.35Å; L216-G224 PolarHBondContact N-O 3.41Å; L216-G224 PolarHBondContact O-N 3.47Å; L216-Y243 HydrophobicContact CB-CD1 3.66Å; L216-Y243 HydrophobicContact CB-CE1 4.09Å; L216-Y243 HydrophobicContact CB-CG 4.24Å; L216-Y243 HydrophobicContact CD1-CD1 4.2Å; L216-Y243 HydrophobicContact CD1-CE1 3.96Å; L216-Y243 HydrophobicContact CD2-CD1 4.07Å; L216-Y243 HydrophobicContact CD2-CD2 4.1Å; L216-Y243 HydrophobicContact CD2-CG 3.8Å; L216-Y243 HydrophobicContact CG-CD1 4.19Å; L216-Y243 HydrophobicContact CG-CE1 4.44Å; L216-Y243 HydrophobicContact CG-CG 4.43Å
217L98.8Very high96.9Very high13 Ų1320.2 Ų20.27%0.06813%0.125CC..EExtended strand (participates in β ladder)trans-101.7124.1175.2-62.9-149.3000110.7Y42 L133 C148 Q149 P215 V221 F222Y42-L217 HydrophobicContact CE1-CD1 4.33Å; Y42-L217 HydrophobicContact CE2-CD1 4.5Å; Y42-L217 WeakPolarHBondContact OH-CD1 3.46Å; L133-L217 HydrophobicContact CD1-CD1 4.36Å; L133-L217 HydrophobicContact CD1-CD2 4.15Å; L133-L217 HydrophobicContact CD2-CD2 3.86Å; C148-L217 CarbonylContact C-O 3.58Å; C148-L217 WeakPolarHBondContact CA-O 3.34Å; C148-L217 WeakPolarHBondContact CB-O 3.47Å; Q149-L217 PolarHBondContact N-O 2.8Å; Q149-L217 PolarHBondContact O-N 3.46Å; Q149-L217 PolarHBondContact OE1-O 2.89Å; P215-L217 HydrophobicContact CB-CD2 4.16Å; L217-V221 CarbonylContact C-O 3.46Å; L217-V221 WeakPolarHBondContact CA-O 3.4Å; L217-F222 HydrophobicContact CD2-CB 3.93Å; L217-F222 HydrophobicContact CD2-CD2 4.24Å; L217-F222 HydrophobicContact CD2-CG 4.31Å
218C98.6Very high97.3Very high3 Ų321 Ų212%0.0213%0.127CC..EExtended strand (participates in β ladder)trans-119.9122.2174.2-55.80000109.1V142 T146 C148 G220 V221 R223V142-C218 HydrophobicContact CG1-CB 4.14Å; T146-C218 HydrophobicContact CG2-CB 4.06Å; C148-C218 HydrophobicContact CB-CB 4.01Å; C148-C218 WeakPolarHBondContact CB-SG 3.37Å; C148-C218 WeakPolarHBondContact SG-CB 3.29Å; C148-C218 CovalentContact SG-SG 2.04Å; C148-C218 PolarHBondContact SG-SG 3.35Å; C218-G220 PolarHBondContact O-N 2.61Å; C218-V221 PolarHBondContact N-O 3.26Å; C218-V221 PolarHBondContact O-N 2.97Å; C218-R223 HydrophobicContact CB-CB 4.42Å; C218-R223 HydrophobicContact CB-CG 3.84Å
219N95.5Very high97.4Very high130 Ų13022.1 Ų22.170%0.69514%0.14SC*.THydrogen-bonded Turntrans49.740.1-171.3-59.1-34.3000112.6V221N219-V221 PolarHBondContact O-N 2.68Å
220G95.3Very high97.5Very high56 Ų5622.6 Ų22.658%0.57714%0.137SC*.THydrogen-bonded Turntrans73.63.6-178.300000115.7C218C218-G220 PolarHBondContact O-N 2.61Å
221V98.4Very high97.3Very high53 Ų5330.6 Ų30.632%0.32117%0.169SC..EExtended strand (participates in β ladder)trans-100.8133.9178-178.30000110P136 L217 C218 N219 R223P136-V221 HydrophobicContact CB-CG1 3.92Å; L217-V221 CarbonylContact C-O 3.46Å; L217-V221 WeakPolarHBondContact CA-O 3.4Å; C218-V221 PolarHBondContact N-O 3.26Å; C218-V221 PolarHBondContact O-N 2.97Å; N219-V221 PolarHBondContact O-N 2.68Å; V221-R223 HydrophobicContact CB-CG 4.46Å; V221-R223 HydrophobicContact CG1-CG 4.38Å; V221-R223 PolarHBondContact O-N 2.77Å; V221-R223 VanDerWaalsContact O-N 3.15Å
222F98.7Very high96.7Very high1 Ų134.7 Ų34.70%0.00419%0.191CC..EExtended strand (participates in β ladder)trans-67.5108.4172.9-170.2-175.1000110A57 I59 L65 L133 L135 P136 P215 L217 G224 V225 L246A57-F222 HydrophobicContact CB-CE1 3.77Å; A57-F222 HydrophobicContact CB-CZ 3.85Å; I59-F222 HydrophobicContact CG2-CE1 3.9Å; L65-F222 HydrophobicContact CD2-CE1 4.04Å; L65-F222 HydrophobicContact CD2-CZ 3.86Å; L133-F222 HydrophobicContact CD1-CB 4.38Å; L133-F222 HydrophobicContact CD2-CB 3.91Å; L133-F222 HydrophobicContact CD2-CD1 3.34Å; L133-F222 HydrophobicContact CD2-CD2 4.11Å; L133-F222 HydrophobicContact CD2-CE1 3.74Å; L133-F222 HydrophobicContact CD2-CE2 4.45Å; L133-F222 HydrophobicContact CD2-CG 3.54Å; L133-F222 HydrophobicContact CD2-CZ 4.28Å; L133-F222 HydrophobicContact CG-CB 4.02Å; L133-F222 HydrophobicContact CG-CD1 3.66Å; L133-F222 HydrophobicContact CG-CE1 4.34Å; L133-F222 HydrophobicContact CG-CG 4.04Å; L135-F222 HydrophobicContact CD2-CD1 4.5Å; P136-F222 VanDerWaalsContact CD-O 3.28Å; P136-F222 WeakPolarHBondContact CD-O 3.43Å; P136-F222 VanDerWaalsContact CG-O 3.24Å; P136-F222 WeakPolarHBondContact CG-O 3.35Å; P215-F222 HydrophobicContact CB-CD2 3.7Å; P215-F222 HydrophobicContact CB-CE1 4.43Å; P215-F222 HydrophobicContact CB-CE2 3.32Å; P215-F222 HydrophobicContact CB-CG 4.43Å; P215-F222 HydrophobicContact CB-CZ 3.72Å; L217-F222 HydrophobicContact CD2-CB 3.93Å; L217-F222 HydrophobicContact CD2-CD2 4.24Å; L217-F222 HydrophobicContact CD2-CG 4.31Å; F222-G224 WeakPolarHBondContact CE2-O 2.89Å; F222-V225 HydrophobicContact CE2-CG2 4.03Å; F222-V225 HydrophobicContact CZ-CG2 4.02Å; F222-L246 HydrophobicContact CB-CD1 4.44Å; F222-L246 HydrophobicContact CD1-CD1 3.94Å; F222-L246 HydrophobicContact CD2-CD1 3.71Å; F222-L246 HydrophobicContact CE1-CD1 4.13Å; F222-L246 HydrophobicContact CE2-CD1 3.87Å; F222-L246 HydrophobicContact CG-CD1 3.74Å; F222-L246 HydrophobicContact CZ-CD1 4.1Å
223R98.8Very high96.4Very high51 Ų5140.4 Ų40.419%0.19221%0.21CC..EExtended strand (participates in β ladder)trans-111.4-26.3-172.7-72.3-58.7-175165.5-3.9114.5D140 V142 L216 C218 V221 L246D140-R223 PolarHBondContact O-NH1 3.22Å; D140-R223 VanDerWaalsContact O-NH1 3.15Å; V142-R223 HydrophobicContact CG2-CB 3.76Å; V142-R223 HydrophobicContact CG2-CG 3.73Å; L216-R223 PolarHBondContact O-N 3.25Å; C218-R223 HydrophobicContact CB-CB 4.42Å; C218-R223 HydrophobicContact CB-CG 3.84Å; V221-R223 HydrophobicContact CB-CG 4.46Å; V221-R223 HydrophobicContact CG1-CG 4.38Å; V221-R223 PolarHBondContact O-N 2.77Å; V221-R223 VanDerWaalsContact O-N 3.15Å; R223-L246 PolarHBondContact O-N 3.36Å
224G98.8Very high96Very high0 Ų040.9 Ų40.90%021%0.213CC..EExtended strand (participates in β ladder)trans-163.2172.3-179.400000113.5L216 F222 I244L216-G224 WeakPolarHBondContact CB-O 3.35Å; L216-G224 PolarHBondContact N-O 3.41Å; L216-G224 PolarHBondContact O-N 3.47Å; F222-G224 WeakPolarHBondContact CE2-O 2.89Å; G224-I244 CarbonylContact C-O 3.43Å; G224-I244 WeakPolarHBondContact CA-O 3.4Å
225V98.9Very high95.6Very high0 Ų041.4 Ų41.40%022%0.219CC..EExtended strand (participates in β ladder)trans-119.9129.1-178.6177.10000109L65 L115 S214 F222 S227 Y243 I244 L246L65-V225 HydrophobicContact CD2-CG2 3.89Å; L65-V225 HydrophobicContact CG-CG2 4.16Å; L115-V225 HydrophobicContact CD2-CB 3.62Å; L115-V225 HydrophobicContact CD2-CG1 4.03Å; L115-V225 HydrophobicContact CD2-CG2 3.53Å; S214-V225 WeakPolarHBondContact O-CA 3.32Å; F222-V225 HydrophobicContact CE2-CG2 4.03Å; F222-V225 HydrophobicContact CZ-CG2 4.02Å; V225-S227 PolarHBondContact O-N 3.15Å; V225-Y243 CarbonylContact O-C 3.47Å; V225-Y243 WeakPolarHBondContact O-CA 3.33Å; V225-I244 PolarHBondContact N-O 3.31Å; V225-I244 PolarHBondContact O-N 3.5Å; V225-L246 HydrophobicContact CG2-CD2 4.19Å
226T98.8Very high95.3Very high4 Ų443.4 Ų43.43%0.02523%0.229CC..EExtended strand (participates in β ladder)trans-57.2127.5179.5-53.30000110.9D211 G213 S214 Y243D211-T226 HydrophobicContact CB-CG2 4.44Å; D211-T226 WeakPolarHBondContact O-CB 3.47Å; G213-T226 PolarHBondContact N-O 2.95Å; S214-T226 PolarHBondContact O-N 2.75Å; S214-T226 PolarHBondContact O-OG1 2.98Å; S214-T226 VanDerWaalsContact O-OG1 3.13Å; T226-Y243 HydrophobicContact CG2-CE1 4.2Å; T226-Y243 VanDerWaalsContact OG1-CE1 3.25Å; T226-Y243 WeakPolarHBondContact OG1-CE1 3.45Å
227S98.5Very high95Very high3 Ų346.1 Ų46.12%0.02125%0.247CC..EExtended strand (participates in β ladder)trans-120.1-66-177.2-1790000112.1H69 D114 V225 V242H69-S227 PolarHBondContact CE1-O 3.2Å; D114-S227 WeakPolarHBondContact CB-OG 3.41Å; D114-S227 WeakPolarHBondContact OD2-CB 3.37Å; D114-S227 PolarHBondContact OD2-OG 3.03Å; V225-S227 PolarHBondContact O-N 3.15Å; S227-V242 PolarHBondContact N-O 3.1Å
228F97.8Very high94.9Very high25 Ų2545.9 Ų45.911%0.1125%0.248CC..EExtended strand (participates in β ladder)trans-151167.1-175.172.2-86.2000113.2H111 Y185 P189 I191 M195 V242H111-F228 HydrophobicContact CB-CD1 3.52Å; H111-F228 HydrophobicContact CB-CE1 3.63Å; H111-F228 HydrophobicContact CB-CG 4.47Å; H111-F228 AromaticContact CD2-CD1 3.83Å; H111-F228 AromaticContact CD2-CG 4Å; H111-F228 AromaticContact CG-CD1 3.61Å; Y185-F228 HydrophobicContact CD1-CE2 4.38Å; Y185-F228 HydrophobicContact CE1-CD2 4.35Å; Y185-F228 AromaticContact CE1-CE2 3.7Å; Y185-F228 HydrophobicContact CE1-CE2 3.7Å; Y185-F228 AromaticContact CZ-CE2 3.93Å; P189-F228 HydrophobicContact CG-CE1 4.49Å; P189-F228 HydrophobicContact CG-CE2 3.59Å; P189-F228 HydrophobicContact CG-CZ 3.48Å; P189-F228 VanDerWaalsContact CG-CZ 3.48Å; I191-F228 HydrophobicContact CD1-CE2 4.43Å; I191-F228 HydrophobicContact CD1-CZ 3.78Å; M195-F228 HydrophobicContact SD-CE1 4.24Å; F228-V242 HydrophobicContact CD1-CB 3.93Å; F228-V242 HydrophobicContact CD1-CG1 4.11Å; F228-V242 HydrophobicContact CD2-CB 4.37Å; F228-V242 HydrophobicContact CD2-CG2 4.36Å; F228-V242 HydrophobicContact CE1-CB 3.61Å; F228-V242 HydrophobicContact CE1-CG1 3.43Å; F228-V242 VanDerWaalsContact CE1-CG1 3.43Å; F228-V242 HydrophobicContact CE1-CG2 4.12Å; F228-V242 HydrophobicContact CE2-CB 4.08Å; F228-V242 HydrophobicContact CE2-CG2 3.78Å; F228-V242 HydrophobicContact CG-CB 4.3Å; F228-V242 HydrophobicContact CZ-CB 3.69Å; F228-V242 HydrophobicContact CZ-CG1 3.71Å; F228-V242 HydrophobicContact CZ-CG2 3.65Å; F228-V242 PolarHBondContact N-O 3.25Å; F228-V242 PolarHBondContact O-N 3.15Å
229G95.2Very high94.7Very high32 Ų3245.8 Ų45.833%0.3325%0.247SC..  trans-144.1-172.3170.100000109.4K231G229-K231 PolarHBondContact O-N 3.42Å
230R92.3Very high94.8Very high75 Ų7539.8 Ų39.828%0.28322%0.215SC..SBendtrans-70125.9169.2-78.8-175.5174.1-175.6-1.2109.9H184 Y185 N232 R233 D236 G238H184-R230 PolarHBondContact O-NH2 3.38Å; Y185-R230 HydrophobicContact CE1-CG 4.32Å; R230-N232 PolarHBondContact O-N 3.03Å; R230-R233 HydrophobicContact CB-CB 3.89Å; R230-R233 CarbonylContact O-C 3.46Å; R230-R233 PolarHBondContact O-N 3.17Å; R230-D236 IonicContact NH1-OD2 3.87Å; R230-G238 PolarHBondContact NE-O 2.86Å; R230-G238 PolarHBondContact NH2-O 3Å
231K88.3Confident95Very high176 Ų17637.1 Ų37.177%0.76519%0.187SC*.THydrogen-bonded Turntrans-52127.3-179-175.7177.3-179.11780111.7G229 R233G229-K231 PolarHBondContact O-N 3.42Å; K231-R233 PolarHBondContact O-N 2.99Å
232N85.6Confident95Very high87 Ų8734.6 Ų34.647%0.46517%0.172SC..THydrogen-bonded Turntrans55.723.8-179.1-55.6-27.3000114.5N158 R230N158-N232 PolarHBondContact OD1-O 3.14Å; R230-N232 PolarHBondContact O-N 3.03Å
233R90.8Very high95Very high137 Ų13734.5 Ų34.552%0.51717%0.172SC..  trans-138.135.4-179.2-62.2-169.8-176.2-162.52.6111.4N158 R230 K231 G235 D236N158-R233 PolarHBondContact OD1-N 2.93Å; R230-R233 HydrophobicContact CB-CB 3.89Å; R230-R233 CarbonylContact O-C 3.46Å; R230-R233 PolarHBondContact O-N 3.17Å; K231-R233 PolarHBondContact O-N 2.99Å; R233-G235 PolarHBondContact O-N 2.77Å; R233-D236 HydrophobicContact CB-CB 3.93Å; R233-D236 IonicContact NH1-OD2 3.81Å; R233-D236 WeakPolarHBondContact O-CB 3.36Å; R233-D236 PolarHBondContact O-N 3.2Å
234C90.8Very high95Very high11 Ų1132.1 Ų32.17%0.07416%0.163CC..THydrogen-bonded Turntrans-54.3136.1171.7-53.10000108.7I30 N158 C208 D236I30-C234 VanDerWaalsContact CD1-C 3.5Å; I30-C234 HydrophobicContact CD1-CB 3.27Å; I30-C234 WeakPolarHBondContact CD1-O 3.36Å; I30-C234 HydrophobicContact CG1-CB 4.35Å; N158-C234 PolarHBondContact ND2-O 3.3Å; N158-C234 VanDerWaalsContact ND2-O 3.14Å; N158-C234 PolarHBondContact OD1-N 3.26Å; C208-C234 WeakPolarHBondContact CA-SG 3.42Å; C208-C234 HydrophobicContact CB-CB 3.58Å; C208-C234 WeakPolarHBondContact CB-SG 3.24Å; C208-C234 WeakPolarHBondContact SG-CB 3.43Å; C208-C234 CovalentContact SG-SG 2.04Å; C208-C234 PolarHBondContact SG-SG 3.15Å; C234-D236 VanDerWaalsContact C-N 3.28Å; C234-D236 PolarHBondContact O-N 3.03Å
235G89.5Confident95Very high11 Ų1132.3 Ų32.311%0.11316%0.164CC..THydrogen-bonded Turntrans78.5-0.1-176.600000115.8G203 G204 D206 R233G203-G235 CarbonylContact C-O 3.56Å; G203-G235 WeakPolarHBondContact CA-O 3.05Å; G204-G235 PolarHBondContact N-O 3.08Å; D206-G235 VanDerWaalsContact CB-N 3.3Å; D206-G235 PolarHBondContact OD2-N 2.99Å; R233-G235 PolarHBondContact O-N 2.77Å
236D93.6Very high95Very high44 Ų4432.4 Ų32.424%0.23516%0.164CC..  trans-67.9125169.3-179.3-23.3000109.2R230 R233 C234 G238 G239R230-D236 IonicContact NH1-OD2 3.87Å; R233-D236 HydrophobicContact CB-CB 3.93Å; R233-D236 IonicContact NH1-OD2 3.81Å; R233-D236 WeakPolarHBondContact O-CB 3.36Å; R233-D236 PolarHBondContact O-N 3.2Å; C234-D236 VanDerWaalsContact C-N 3.28Å; C234-D236 PolarHBondContact O-N 3.03Å; D236-G238 PolarHBondContact O-N 2.83Å; D236-G238 VanDerWaalsContact O-N 3.15Å; D236-G238 WeakPolarHBondContact OD1-CA 3.14Å; D236-G238 PolarHBondContact OD1-N 3.29Å; D236-G239 CarbonylContact O-C 3.6Å; D236-G239 PolarHBondContact O-N 3.04Å
237P93.1Very high95Very high57 Ų5732.8 Ų32.837%0.3717%0.167SC..THydrogen-bonded Turntrans-59.3-27179.523.5-32.7000113.3H184 G239H184-P237 PolarHBondContact CD2-O 2.04Å; H184-P237 PolarHBondContact NE2-O 2.83Å; P237-G239 PolarHBondContact O-N 3.19Å
238G95.1Very high95Very high8 Ų840.4 Ų40.48%0.08220%0.2CC..THydrogen-bonded Turntrans-79.41175.600000114.3K183 H184 R230 D236K183-G238 WeakPolarHBondContact O-CA 3.19Å; H184-G238 CarbonylContact C-O 3.47Å; H184-G238 VanDerWaalsContact CA-O 3.22Å; H184-G238 WeakPolarHBondContact CA-O 3.33Å; R230-G238 PolarHBondContact NE-O 2.86Å; R230-G238 PolarHBondContact NH2-O 3Å; D236-G238 PolarHBondContact O-N 2.83Å; D236-G238 VanDerWaalsContact O-N 3.15Å; D236-G238 WeakPolarHBondContact OD1-CA 3.14Å; D236-G238 PolarHBondContact OD1-N 3.29Å
239G95.9Very high95Very high0 Ų043.2 Ų43.20%021%0.212CC..SBendtrans-147.158.8179.700000112.9D236 P237D236-G239 CarbonylContact O-C 3.6Å; D236-G239 PolarHBondContact O-N 3.04Å; P237-G239 PolarHBondContact O-N 3.19Å
240P97.4Very high95.1Very high4 Ų441.7 Ų41.73%0.02620%0.197CC..  trans-61.7146.3-179.229.3-36.5000111I174 Y185 C197 V242I174-P240 HydrophobicContact CD1-CB 3.52Å; I174-P240 HydrophobicContact CD1-CG 3.81Å; Y185-P240 HydrophobicContact CE2-CG 4.37Å; Y185-P240 PolarHBondContact OH-O 3.17Å; C197-P240 HydrophobicContact CB-CG 4.23Å; P240-V242 PolarHBondContact O-N 3.42Å
241G98.1Very high95.4Very high0 Ų038.8 Ų38.80%019%0.187CC..EExtended strand (participates in β ladder)trans-51137.7177.300000113.5C197 A198 D206 Y243C197-G241 WeakPolarHBondContact CA-O 3.17Å; A198-G241 PolarHBondContact N-O 3.44Å; A198-G241 PolarHBondContact O-N 2.96Å; D206-G241 VanDerWaalsContact OD1-CA 3.31Å; D206-G241 WeakPolarHBondContact OD1-CA 3.36Å; D206-G241 PolarHBondContact OD1-N 2.97Å; D206-G241 VanDerWaalsContact OD1-N 3.14Å; G241-Y243 WeakPolarHBondContact O-CD2 3.02Å; G241-Y243 VanDerWaalsContact O-CE2 3.27Å; G241-Y243 WeakPolarHBondContact O-CE2 3.36Å
242V98.8Very high95.9Very high0 Ų033.7 Ų33.70%017%0.173CC..EExtended strand (participates in β ladder)trans-110.3132.2179.1-178.30000109.6Y185 I191 M195 V196 S227 F228 P240Y185-V242 HydrophobicContact CD2-CG2 4.5Å; Y185-V242 HydrophobicContact CE2-CG2 3.59Å; Y185-V242 WeakPolarHBondContact OH-CG2 3.3Å; I191-V242 HydrophobicContact CD1-CG1 4.24Å; I191-V242 HydrophobicContact CD1-CG2 3.8Å; M195-V242 HydrophobicContact CB-CG1 3.97Å; M195-V242 HydrophobicContact CG-CG1 4.23Å; M195-V242 HydrophobicContact SD-CG1 3.91Å; V196-V242 WeakPolarHBondContact O-CA 3.38Å; S227-V242 PolarHBondContact N-O 3.1Å; F228-V242 HydrophobicContact CD1-CB 3.93Å; F228-V242 HydrophobicContact CD1-CG1 4.11Å; F228-V242 HydrophobicContact CD2-CB 4.37Å; F228-V242 HydrophobicContact CD2-CG2 4.36Å; F228-V242 HydrophobicContact CE1-CB 3.61Å; F228-V242 HydrophobicContact CE1-CG1 3.43Å; F228-V242 VanDerWaalsContact CE1-CG1 3.43Å; F228-V242 HydrophobicContact CE1-CG2 4.12Å; F228-V242 HydrophobicContact CE2-CB 4.08Å; F228-V242 HydrophobicContact CE2-CG2 3.78Å; F228-V242 HydrophobicContact CG-CB 4.3Å; F228-V242 HydrophobicContact CZ-CB 3.69Å; F228-V242 HydrophobicContact CZ-CG1 3.71Å; F228-V242 HydrophobicContact CZ-CG2 3.65Å; F228-V242 PolarHBondContact N-O 3.25Å; F228-V242 PolarHBondContact O-N 3.15Å; P240-V242 PolarHBondContact O-N 3.42Å
243Y98.9Very high96.5Very high0 Ų030.4 Ų30.40%015%0.154CC..EExtended strand (participates in β ladder)trans-124.3138.8-175.8-53.5-104.1000109.2V150 I171 M195 V196 A198 S207 L216 V225 T226 G241 L245V150-Y243 HydrophobicContact CB-CE1 4.33Å; V150-Y243 HydrophobicContact CG2-CE1 4.11Å; I171-Y243 HydrophobicContact CD1-CE2 4.17Å; I171-Y243 WeakPolarHBondContact CD1-OH 3.46Å; M195-Y243 CarbonylContact C-O 3.46Å; M195-Y243 VanDerWaalsContact CA-O 3.29Å; M195-Y243 WeakPolarHBondContact CA-O 3.28Å; V196-Y243 PolarHBondContact N-O 3.44Å; V196-Y243 PolarHBondContact O-N 3.31Å; A198-Y243 HydrophobicContact CB-CD2 4.15Å; A198-Y243 HydrophobicContact CB-CE2 3.72Å; S207-Y243 PolarHBondContact OG-OH 2.85Å; L216-Y243 HydrophobicContact CB-CD1 3.66Å; L216-Y243 HydrophobicContact CB-CE1 4.09Å; L216-Y243 HydrophobicContact CB-CG 4.24Å; L216-Y243 HydrophobicContact CD1-CD1 4.2Å; L216-Y243 HydrophobicContact CD1-CE1 3.96Å; L216-Y243 HydrophobicContact CD2-CD1 4.07Å; L216-Y243 HydrophobicContact CD2-CD2 4.1Å; L216-Y243 HydrophobicContact CD2-CG 3.8Å; L216-Y243 HydrophobicContact CG-CD1 4.19Å; L216-Y243 HydrophobicContact CG-CE1 4.44Å; L216-Y243 HydrophobicContact CG-CG 4.43Å; V225-Y243 CarbonylContact O-C 3.47Å; V225-Y243 WeakPolarHBondContact O-CA 3.33Å; T226-Y243 HydrophobicContact CG2-CE1 4.2Å; T226-Y243 VanDerWaalsContact OG1-CE1 3.25Å; T226-Y243 WeakPolarHBondContact OG1-CE1 3.45Å; G241-Y243 WeakPolarHBondContact O-CD2 3.02Å; G241-Y243 VanDerWaalsContact O-CE2 3.27Å; G241-Y243 WeakPolarHBondContact O-CE2 3.36Å; Y243-L245 PolarHBondContact O-N 2.98Å
244I98.9Very high96.9Very high0 Ų023.9 Ų23.90%013%0.129CC..EExtended strand (participates in β ladder)trans-72.6116.6172.4-49.7-51.4000107.8H111 D114 L115 M195 G224 V225 L246 Y250H111-I244 WeakPolarHBondContact O-CD1 3.43Å; D114-I244 HydrophobicContact CB-CD1 3.96Å; D114-I244 HydrophobicContact CB-CG1 3.91Å; L115-I244 HydrophobicContact CD1-CG2 3.77Å; L115-I244 HydrophobicContact CD2-CB 4.15Å; L115-I244 HydrophobicContact CD2-CG2 4.27Å; L115-I244 HydrophobicContact CG-CB 4.19Å; L115-I244 HydrophobicContact CG-CG1 4.49Å; L115-I244 HydrophobicContact CG-CG2 3.85Å; M195-I244 HydrophobicContact CE-CD1 4.39Å; M195-I244 HydrophobicContact CG-CD1 4.17Å; G224-I244 CarbonylContact C-O 3.43Å; G224-I244 WeakPolarHBondContact CA-O 3.4Å; V225-I244 PolarHBondContact N-O 3.31Å; V225-I244 PolarHBondContact O-N 3.5Å; I244-L246 PolarHBondContact O-N 3.44Å; I244-Y250 HydrophobicContact CG2-CD2 4.11Å; I244-Y250 HydrophobicContact CG2-CE2 3.65Å
245L98.9Very high97.2Very high5 Ų527 Ų273%0.02615%0.145CC..EExtended strand (participates in β ladder)trans-64.3132.6177.5178.768.3000108.8D141 V142 M193 N194 V196 Y243 S247 Y250D141-L245 HydrophobicContact CB-CD2 4.31Å; V142-L245 HydrophobicContact CG2-CD1 4.21Å; M193-L245 WeakPolarHBondContact O-CD2 3.22Å; N194-L245 WeakPolarHBondContact O-CB 3.29Å; N194-L245 PolarHBondContact O-N 2.9Å; V196-L245 HydrophobicContact CG1-CB 4.32Å; V196-L245 HydrophobicContact CG1-CD1 3.95Å; Y243-L245 PolarHBondContact O-N 2.98Å; L245-S247 PolarHBondContact O-N 3.28Å; L245-Y250 WeakPolarHBondContact O-CD2 3.24Å
246L98.8Very high97.6Very high2 Ų232.8 Ų32.81%0.0117%0.17CC..  trans-73.863.7170.5-65.1-176.2000110.7L65 L135 P136 G139 F222 R223 V225 I244 L251 I254L65-L246 HydrophobicContact CD2-CD2 4.02Å; L135-L246 HydrophobicContact CD2-CD1 4.44Å; P136-L246 HydrophobicContact CG-CB 3.98Å; P136-L246 HydrophobicContact CG-CD1 4.12Å; G139-L246 WeakPolarHBondContact CA-O 3.18Å; F222-L246 HydrophobicContact CB-CD1 4.44Å; F222-L246 HydrophobicContact CD1-CD1 3.94Å; F222-L246 HydrophobicContact CD2-CD1 3.71Å; F222-L246 HydrophobicContact CE1-CD1 4.13Å; F222-L246 HydrophobicContact CE2-CD1 3.87Å; F222-L246 HydrophobicContact CG-CD1 3.74Å; F222-L246 HydrophobicContact CZ-CD1 4.1Å; R223-L246 PolarHBondContact O-N 3.36Å; V225-L246 HydrophobicContact CG2-CD2 4.19Å; I244-L246 PolarHBondContact O-N 3.44Å; L246-L251 HydrophobicContact CB-CD2 4.13Å; L246-L251 HydrophobicContact CB-CG 4.46Å; L246-L251 WeakPolarHBondContact O-CD1 3.33Å; L246-I254 HydrophobicContact CD2-CD1 4.13Å
247S98.6Very high97.8Very high12 Ų1231.6 Ų31.68%0.08416%0.164CC..  trans-69167.1-179.978.40000111.5N194 L245 K249 Y250 L251N194-S247 PolarHBondContact OD1-OG 3.41Å; N194-S247 VanDerWaalsContact OD1-OG 3.12Å; L245-S247 PolarHBondContact O-N 3.28Å; S247-K249 PolarHBondContact O-N 3.34Å; S247-K249 VanDerWaalsContact O-N 3.11Å; S247-Y250 PolarHBondContact O-N 2.74Å; S247-Y250 VanDerWaalsContact OG-CD2 3.29Å; S247-Y250 WeakPolarHBondContact OG-CD2 3.42Å; S247-L251 WeakPolarHBondContact O-CG 3.49Å; S247-L251 PolarHBondContact O-N 2.98Å
248K98.1Very high98Very high163 Ų16330.5 Ų30.571%0.70916%0.155SC*.Hα-helixtrans-52.5-36.4177.4-174.4179.9178.9-177.20112.4S252K248-S252 WeakPolarHBondContact O-CB 3.35Å; K248-S252 PolarHBondContact O-N 3.36Å; K248-S252 VanDerWaalsContact O-N 3.08Å; K248-S252 PolarHBondContact O-OG 3.45Å
249K97.9Very high97.9Very high84 Ų8437.6 Ų37.637%0.36518%0.184SC..Hα-helixtrans-59.4-51.6177.2-176-17674.3178.70111.2Y103 E112 N194 S247 W253Y103-K249 WeakPolarHBondContact OH-CD 3.22Å; Y103-K249 VanDerWaalsContact OH-CE 3.32Å; Y103-K249 WeakPolarHBondContact OH-CE 3.48Å; E112-K249 IonicContact OE1-NZ 3.55Å; N194-K249 PolarHBondContact ND2-NZ 3.1Å; S247-K249 PolarHBondContact O-N 3.34Å; S247-K249 VanDerWaalsContact O-N 3.11Å; K249-W253 PolarHBondContact O-N 3.32Å
250Y98.7Very high97.4Very high0 Ų040.8 Ų40.80%022%0.217CC..Hα-helixtrans-75.5-36.2-176.4-58.2-60.6000112.8Y103 G113 L115 N194 I244 L245 S247 S252 W253 I254Y103-Y250 HydrophobicContact CD1-CD1 4.37Å; Y103-Y250 AromaticContact CD1-CE1 3.87Å; Y103-Y250 HydrophobicContact CD1-CE1 3.87Å; Y103-Y250 HydrophobicContact CD2-CD1 4.25Å; Y103-Y250 HydrophobicContact CE1-CD1 4.09Å; Y103-Y250 AromaticContact CE1-CE1 3.47Å; Y103-Y250 HydrophobicContact CE1-CE1 3.47Å; Y103-Y250 VanDerWaalsContact CE1-CE1 3.47Å; Y103-Y250 AromaticContact CE2-CD1 3.98Å; Y103-Y250 HydrophobicContact CE2-CD1 3.98Å; Y103-Y250 HydrophobicContact CE2-CE1 4.21Å; Y103-Y250 HydrophobicContact CG-CD1 4.44Å; Y103-Y250 HydrophobicContact CG-CE1 4.37Å; Y103-Y250 AromaticContact CZ-CD1 3.88Å; Y103-Y250 AromaticContact CZ-CE1 3.66Å; G113-Y250 WeakPolarHBondContact CA-OH 3.43Å; G113-Y250 PolarHBondContact N-OH 3.22Å; L115-Y250 HydrophobicContact CD1-CD1 3.59Å; L115-Y250 HydrophobicContact CD1-CD2 4.12Å; L115-Y250 HydrophobicContact CD1-CE1 4.17Å; L115-Y250 HydrophobicContact CD1-CG 3.55Å; N194-Y250 HydrophobicContact CB-CE2 3.69Å; N194-Y250 WeakPolarHBondContact CB-OH 3.21Å; I244-Y250 HydrophobicContact CG2-CD2 4.11Å; I244-Y250 HydrophobicContact CG2-CE2 3.65Å; L245-Y250 WeakPolarHBondContact O-CD2 3.24Å; S247-Y250 PolarHBondContact O-N 2.74Å; S247-Y250 VanDerWaalsContact OG-CD2 3.29Å; S247-Y250 WeakPolarHBondContact OG-CD2 3.42Å; Y250-S252 VanDerWaalsContact C-N 3.32Å; Y250-S252 PolarHBondContact O-N 2.83Å; Y250-W253 PolarHBondContact O-N 2.79Å; Y250-I254 VanDerWaalsContact O-CG1 3.28Å; Y250-I254 WeakPolarHBondContact O-CG1 3.41Å; Y250-I254 PolarHBondContact O-N 3.03Å
251L98.6Very high96.1Very high14 Ų1441.9 Ų41.97%0.07323%0.226CC..Hα-helixtrans-59.7-43.8173.4-67.6173.6000111.6L135 P136 L246 S247 W253 I254 I255L135-L251 HydrophobicContact CB-CD2 4.2Å; L135-L251 HydrophobicContact CD2-CD2 4.35Å; P136-L251 HydrophobicContact CG-CD1 4.02Å; P136-L251 HydrophobicContact CG-CD2 3.84Å; P136-L251 HydrophobicContact CG-CG 4.49Å; L246-L251 HydrophobicContact CB-CD2 4.13Å; L246-L251 HydrophobicContact CB-CG 4.46Å; L246-L251 WeakPolarHBondContact O-CD1 3.33Å; S247-L251 WeakPolarHBondContact O-CG 3.49Å; S247-L251 PolarHBondContact O-N 2.98Å; L251-W253 VanDerWaalsContact C-N 3.33Å; L251-W253 PolarHBondContact O-N 3.08Å; L251-I254 PolarHBondContact O-N 2.99Å; L251-I255 WeakPolarHBondContact O-CB 3.29Å; L251-I255 WeakPolarHBondContact O-CD1 3.36Å; L251-I255 VanDerWaalsContact O-CG1 3.24Å; L251-I255 WeakPolarHBondContact O-CG1 3.33Å; L251-I255 PolarHBondContact O-N 3.19Å
252S98Very high94Very high68 Ų6850.1 Ų50.148%0.47628%0.276SS..Hα-helixtrans-59.1-44.5174.9-670000111.9K248 Y250 M256K248-S252 WeakPolarHBondContact O-CB 3.35Å; K248-S252 PolarHBondContact O-N 3.36Å; K248-S252 VanDerWaalsContact O-N 3.08Å; K248-S252 PolarHBondContact O-OG 3.45Å; Y250-S252 VanDerWaalsContact C-N 3.32Å; Y250-S252 PolarHBondContact O-N 2.83Å; S252-M256 WeakPolarHBondContact O-CB 3.27Å; S252-M256 PolarHBondContact O-N 2.94Å
253W98.6Very high93.8Very high19 Ų1952.6 Ų52.67%0.07229%0.29CS..Hα-helixtrans-60.9-49.8175.6166.774.2000111.8L65 F101 Y103 L115 L117 K249 Y250 L251 I255 M256 T257L65-W253 HydrophobicContact CD1-CZ3 4.43Å; F101-W253 VanDerWaalsContact O-CZ2 3.27Å; F101-W253 WeakPolarHBondContact O-CZ2 3.28Å; Y103-W253 HydrophobicContact CD2-CB 4.24Å; Y103-W253 AromaticContact CD2-CD1 3.9Å; Y103-W253 AromaticContact CD2-CD2 3.53Å; Y103-W253 HydrophobicContact CD2-CD2 3.53Å; Y103-W253 AromaticContact CD2-CE2 3.83Å; Y103-W253 AromaticContact CD2-CE3 3.92Å; Y103-W253 HydrophobicContact CD2-CE3 3.92Å; Y103-W253 AromaticContact CD2-CG 3.61Å; Y103-W253 HydrophobicContact CD2-CG 3.61Å; Y103-W253 HydrophobicContact CD2-CZ2 4.48Å; Y103-W253 HydrophobicContact CE2-CB 4.02Å; Y103-W253 HydrophobicContact CE2-CD2 4.22Å; Y103-W253 AromaticContact CE2-CG 3.84Å; Y103-W253 HydrophobicContact CE2-CG 3.84Å; L115-W253 HydrophobicContact CB-CH2 4.39Å; L115-W253 HydrophobicContact CB-CZ3 3.96Å; L117-W253 HydrophobicContact CB-CH2 4.25Å; L117-W253 HydrophobicContact CD1-CH2 3.97Å; L117-W253 HydrophobicContact CD1-CZ2 4.22Å; L117-W253 HydrophobicContact CD1-CZ3 4.26Å; L117-W253 HydrophobicContact CG-CH2 3.73Å; L117-W253 HydrophobicContact CG-CZ2 4.35Å; L117-W253 HydrophobicContact CG-CZ3 4.13Å; K249-W253 PolarHBondContact O-N 3.32Å; Y250-W253 PolarHBondContact O-N 2.79Å; L251-W253 VanDerWaalsContact C-N 3.33Å; L251-W253 PolarHBondContact O-N 3.08Å; W253-I255 PolarHBondContact O-N 3.37Å; W253-M256 PolarHBondContact O-N 3.38Å; W253-T257 PolarHBondContact NE1-OG1 3.21Å; W253-T257 WeakPolarHBondContact O-CB 3.32Å; W253-T257 PolarHBondContact O-N 2.75Å; W253-T257 PolarHBondContact O-OG1 3.15Å; W253-T257 VanDerWaalsContact O-OG1 3.11Å
254I98.7Very high93.5Very high0 Ų055.4 Ų55.40%031%0.305CS..Hα-helixtrans-56-51.4-180-67.9162.7000110.5I59 L65 L117 L135 L246 Y250 L251 M256 T257 I258I59-I254 HydrophobicContact CD1-CG2 3.75Å; L65-I254 HydrophobicContact CD1-CD1 4.23Å; L65-I254 HydrophobicContact CD1-CG1 4.42Å; L65-I254 HydrophobicContact CD2-CD1 3.86Å; L117-I254 HydrophobicContact CD1-CB 4.43Å; L117-I254 HydrophobicContact CD1-CG1 4.45Å; L117-I254 HydrophobicContact CD1-CG2 4.25Å; L117-I254 HydrophobicContact CD2-CG2 4.3Å; L135-I254 HydrophobicContact CD1-CB 4.44Å; L135-I254 HydrophobicContact CD1-CG2 3.58Å; L135-I254 HydrophobicContact CD2-CD1 4.22Å; L135-I254 HydrophobicContact CD2-CG2 4.42Å; L246-I254 HydrophobicContact CD2-CD1 4.13Å; Y250-I254 VanDerWaalsContact O-CG1 3.28Å; Y250-I254 WeakPolarHBondContact O-CG1 3.41Å; Y250-I254 PolarHBondContact O-N 3.03Å; L251-I254 PolarHBondContact O-N 2.99Å; I254-M256 PolarHBondContact O-N 3.47Å; I254-T257 PolarHBondContact O-N 2.76Å; I254-I258 HydrophobicContact CG2-CD1 3.79Å; I254-I258 WeakPolarHBondContact O-CG1 3.27Å; I254-I258 PolarHBondContact O-N 2.96Å
255I97.9Very high93.2Very high77 Ų7758.4 Ų58.440%0.39532%0.322SS..Hα-helixtrans-64-42-177.3-66.1165.1000111L135 L251 W253 K259L135-I255 HydrophobicContact CD1-CG1 4.45Å; L251-I255 WeakPolarHBondContact O-CB 3.29Å; L251-I255 WeakPolarHBondContact O-CD1 3.36Å; L251-I255 VanDerWaalsContact O-CG1 3.24Å; L251-I255 WeakPolarHBondContact O-CG1 3.33Å; L251-I255 PolarHBondContact O-N 3.19Å; W253-I255 PolarHBondContact O-N 3.37Å; I255-K259 HydrophobicContact CG2-CD 4.07Å; I255-K259 WeakPolarHBondContact O-CB 3.39Å; I255-K259 VanDerWaalsContact O-CG 3.32Å; I255-K259 WeakPolarHBondContact O-CG 3.45Å; I255-K259 PolarHBondContact O-N 3.29Å
256M97.6Very high92.9Very high131 Ų13161.6 Ų61.665%0.64534%0.339SS*.Hα-helixtrans-66.8-42179.4-174.2178.57800111.7S252 W253 I254 K259 G260S252-M256 WeakPolarHBondContact O-CB 3.27Å; S252-M256 PolarHBondContact O-N 2.94Å; W253-M256 PolarHBondContact O-N 3.38Å; I254-M256 PolarHBondContact O-N 3.47Å; M256-K259 PolarHBondContact O-N 3.42Å; M256-G260 PolarHBondContact O-N 3.07Å
257T98.1Very high92.5Very high19 Ų1965.3 Ų65.312%0.11736%0.36CS..Hα-helixtrans-63.9-45.3177.6-65.40000111.7W63 F101 L117 W253 I254 K259 G260 A261W63-T257 HydrophobicContact CH2-CG2 4.2Å; W63-T257 HydrophobicContact CZ3-CG2 4.16Å; F101-T257 HydrophobicContact CB-CG2 3.91Å; F101-T257 HydrophobicContact CD1-CG2 3.66Å; F101-T257 HydrophobicContact CD2-CG2 4.38Å; F101-T257 HydrophobicContact CE1-CG2 4.19Å; F101-T257 HydrophobicContact CG-CG2 3.75Å; L117-T257 HydrophobicContact CD1-CG2 3.71Å; W253-T257 PolarHBondContact NE1-OG1 3.21Å; W253-T257 WeakPolarHBondContact O-CB 3.32Å; W253-T257 PolarHBondContact O-N 2.75Å; W253-T257 PolarHBondContact O-OG1 3.15Å; W253-T257 VanDerWaalsContact O-OG1 3.11Å; I254-T257 PolarHBondContact O-N 2.76Å; T257-K259 PolarHBondContact O-N 2.83Å; T257-G260 PolarHBondContact O-N 2.89Å; T257-A261 VanDerWaalsContact O-CB 3.3Å; T257-A261 WeakPolarHBondContact O-CB 3.38Å; T257-A261 PolarHBondContact O-N 2.68Å
258I96.6Very high92.1Very high35 Ų3568.9 Ų68.918%0.17938%0.378CS..Hα-helixtrans-61.6-46.4177.5-67.2169.8000110.4I59 W63 L117 I254I59-I258 HydrophobicContact CD1-CD1 3.82Å; W63-I258 HydrophobicContact CD2-CG1 3.77Å; W63-I258 HydrophobicContact CE3-CG1 4.08Å; W63-I258 HydrophobicContact CG-CD1 4.36Å; W63-I258 HydrophobicContact CG-CG1 4.02Å; L117-I258 HydrophobicContact CD1-CG1 4.42Å; I254-I258 HydrophobicContact CG2-CD1 3.79Å; I254-I258 WeakPolarHBondContact O-CG1 3.27Å; I254-I258 PolarHBondContact O-N 2.96Å
259K93.1Very high91.7Very high156 Ų15662.1 Ų62.168%0.67836%0.355SS*.Hα-helixtrans-66.6-36.6-179.8-73.9179.3179.2-176.20113.7I255 M256 T257I255-K259 HydrophobicContact CG2-CD 4.07Å; I255-K259 WeakPolarHBondContact O-CB 3.39Å; I255-K259 VanDerWaalsContact O-CG 3.32Å; I255-K259 WeakPolarHBondContact O-CG 3.45Å; I255-K259 PolarHBondContact O-N 3.29Å; M256-K259 PolarHBondContact O-N 3.42Å; T257-K259 PolarHBondContact O-N 2.83Å
260G84.6Confident91.2Very high68 Ų6860.5 Ų60.570%0.70135%0.354SS*.Hα-helixtrans-84.8-7.2-176.500000114.9M256 T257M256-G260 PolarHBondContact O-N 3.07Å; T257-G260 PolarHBondContact O-N 2.89Å
261A71.4Confident90.6Very high27 Ų2765.5 Ų65.522%0.22338%0.383CS..THydrogen-bonded Turntrans-100.4-2.4177.200000113.4W63 F101 T257W63-A261 HydrophobicContact CH2-CB 3.64Å; W63-A261 HydrophobicContact CZ2-CB 3.59Å; F101-A261 HydrophobicContact CZ-CB 3.94Å; T257-A261 VanDerWaalsContact O-CB 3.3Å; T257-A261 WeakPolarHBondContact O-CB 3.38Å; T257-A261 PolarHBondContact O-N 2.68Å
262V53.7Low89.8Confident172 Ų17270.2 Ų70.2100%1.04241%0.412SS*.  trans-83.90168.4178.90000109.4

Retrieved 262 of 262 residues in 187.4 ms (Link to these results)