A0A096MR14_PAPAN Loading...

Presenilin

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins. The holoprotein functions as a calcium-leak channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is involved in calcium homeostasis. Is a regulator of mitochondrion-endoplasmic reticulum membrane tethering and modulates calcium ions shuttling between ER and mitochondria. Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

AlphaFold DB , UniProt , Accession A0A096MR14, Species PAPAN (Papio anubis, Olive baboon), Gene PSEN2, Length 481 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.4	Very low	41.7	Very low	163 Å²	163	131.4 Å²	131.4	80%	0.803	62%	0.616	S	S	*	*				0	-51.4	0	-153.2	170.3	-169.7	0	0	111.7	A3 R4 I5 I153	M1-A3 VanDerWaalsContact C-N 3.32Å; M1-A3 PolarHBondContact O-N 3.38Å; M1-R4 WeakPolarHBondContact O-CA 3.15Å; M1-R4 WeakPolarHBondContact O-CB 3.31Å; M1-R4 PolarHBondContact O-N 2.93Å; M1-I5 HydrophobicContact CG-CD1 4.3Å; M1-I5 PolarHBondContact O-N 3.21Å; M1-I153 HydrophobicContact SD-CD1 3.94Å
2	L	29.4	Very low	41.5	Very low	141 Å²	141	125.4 Å²	125.4	74%	0.738	60%	0.598	S	S	*	*	H	α-helix	trans	-51	-45.1	172	-129.7	84.9	0	0	0	113.5	R4 I5 V6	L2-R4 PolarHBondContact O-N 3.13Å; L2-I5 PolarHBondContact O-N 3.49Å; L2-V6 WeakPolarHBondContact O-CB 3.25Å; L2-V6 VanDerWaalsContact O-CG2 3.28Å; L2-V6 WeakPolarHBondContact O-CG2 3.39Å; L2-V6 PolarHBondContact O-N 3.4Å
3	A	30.6	Very low	41.5	Very low	60 Å²	60	126.8 Å²	126.8	50%	0.496	61%	0.61	S	S	.	*	H	α-helix	trans	-68.3	-17.4	176.9	0	0	0	0	0	114.6	M1 R7	M1-A3 VanDerWaalsContact C-N 3.32Å; M1-A3 PolarHBondContact O-N 3.38Å; A3-R7 WeakPolarHBondContact O-CB 3.47Å; A3-R7 WeakPolarHBondContact O-CG 3.44Å; A3-R7 PolarHBondContact O-N 3.16Å; A3-R7 PolarHBondContact O-NE 3.04Å
4	R	39.8	Very low	41.6	Very low	190 Å²	190	128.4 Å²	128.4	72%	0.717	62%	0.616	S	S	*	*	H	α-helix	trans	-87.6	-34.9	172.9	-72.9	-174.5	175	179.9	-1.9	110.7	M1 L2 R7 F8	M1-R4 WeakPolarHBondContact O-CA 3.15Å; M1-R4 WeakPolarHBondContact O-CB 3.31Å; M1-R4 PolarHBondContact O-N 2.93Å; L2-R4 PolarHBondContact O-N 3.13Å; R4-R7 PolarHBondContact O-N 3.14Å; R4-F8 WeakPolarHBondContact O-CB 3.25Å; R4-F8 PolarHBondContact O-N 2.87Å
5	I	40.1	Very low	41.5	Very low	94 Å²	94	129.3 Å²	129.3	48%	0.482	63%	0.625	S	S	.	*	H	α-helix	trans	-68.8	-43.3	173.3	-65.7	166.6	0	0	0	110.8	M1 L2 R7 F8 A9	M1-I5 HydrophobicContact CG-CD1 4.3Å; M1-I5 PolarHBondContact O-N 3.21Å; L2-I5 PolarHBondContact O-N 3.49Å; I5-R7 VanDerWaalsContact C-N 3.33Å; I5-R7 PolarHBondContact O-N 3.36Å; I5-F8 PolarHBondContact O-N 3.35Å; I5-A9 WeakPolarHBondContact O-CB 3.33Å; I5-A9 PolarHBondContact O-N 3.3Å
6	V	49.5	Very low	41.1	Very low	82 Å²	82	131.8 Å²	131.8	50%	0.497	63%	0.632	S	S	.	*	H	α-helix	trans	-65.4	-36.1	173.7	173.3	0	0	0	0	111.4	L2 R10	L2-V6 WeakPolarHBondContact O-CB 3.25Å; L2-V6 VanDerWaalsContact O-CG2 3.28Å; L2-V6 WeakPolarHBondContact O-CG2 3.39Å; L2-V6 PolarHBondContact O-N 3.4Å; V6-R10 VanDerWaalsContact O-CB 3.31Å; V6-R10 WeakPolarHBondContact O-CB 3.33Å; V6-R10 PolarHBondContact O-N 3.16Å
7	R	44.3	Very low	40.6	Very low	159 Å²	159	130.6 Å²	130.6	60%	0.6	64%	0.637	S	S	*	*	H	α-helix	trans	-69.7	-34.2	173	-89	-177.2	-78.1	174.3	-12.9	112.9	A3 R4 I5 R11	A3-R7 WeakPolarHBondContact O-CB 3.47Å; A3-R7 WeakPolarHBondContact O-CG 3.44Å; A3-R7 PolarHBondContact O-N 3.16Å; A3-R7 PolarHBondContact O-NE 3.04Å; R4-R7 PolarHBondContact O-N 3.14Å; I5-R7 VanDerWaalsContact C-N 3.33Å; I5-R7 PolarHBondContact O-N 3.36Å; R7-R11 WeakPolarHBondContact O-CB 3.28Å; R7-R11 PolarHBondContact O-N 2.98Å
8	F	52.3	Low	40.8	Very low	145 Å²	145	129.3 Å²	129.3	64%	0.636	65%	0.651	S	S	*	*	H	α-helix	trans	-69.3	-45.6	174.5	-174.4	-101.7	0	0	0	110.8	R4 I5 R10 R11 C12	R4-F8 WeakPolarHBondContact O-CB 3.25Å; R4-F8 PolarHBondContact O-N 2.87Å; I5-F8 PolarHBondContact O-N 3.35Å; F8-R10 VanDerWaalsContact C-N 3.34Å; F8-R10 PolarHBondContact O-N 3.04Å; F8-R11 PolarHBondContact O-N 3.41Å; F8-R11 VanDerWaalsContact O-N 3.16Å; F8-C12 PolarHBondContact O-N 2.86Å; F8-C12 PolarHBondContact O-SG 2.92Å; F8-C12 VanDerWaalsContact O-SG 3.33Å
9	A	41.1	Very low	40.3	Very low	56 Å²	56	134.9 Å²	134.9	46%	0.463	66%	0.664	S	S	.	*	H	α-helix	trans	-60.6	-40.1	173.5	0	0	0	0	0	112.5	I5 C12 L13	I5-A9 WeakPolarHBondContact O-CB 3.33Å; I5-A9 PolarHBondContact O-N 3.3Å; A9-C12 PolarHBondContact O-N 3.21Å; A9-L13 PolarHBondContact O-N 2.84Å
10	R	47.8	Very low	39.9	Very low	171 Å²	171	135.9 Å²	135.9	65%	0.645	67%	0.672	S	S	*	*	H	α-helix	trans	-65.6	-39.5	174.1	-170	179.6	-78	-174.2	-5.9	112.1	V6 F8 L13 E14	V6-R10 VanDerWaalsContact O-CB 3.31Å; V6-R10 WeakPolarHBondContact O-CB 3.33Å; V6-R10 PolarHBondContact O-N 3.16Å; F8-R10 VanDerWaalsContact C-N 3.34Å; F8-R10 PolarHBondContact O-N 3.04Å; R10-L13 PolarHBondContact O-N 2.84Å; R10-E14 PolarHBondContact O-N 3.37Å; R10-E14 VanDerWaalsContact O-N 3.16Å
11	R	45.5	Very low	39.6	Very low	184 Å²	184	135.6 Å²	135.6	69%	0.694	68%	0.68	S	S	*	*	H	α-helix	trans	-66.1	-36.1	173	-99.1	-176.8	-179.4	-173.4	-1.1	113.2	R7 F8 L13 E14 L15	R7-R11 WeakPolarHBondContact O-CB 3.28Å; R7-R11 PolarHBondContact O-N 2.98Å; F8-R11 PolarHBondContact O-N 3.41Å; F8-R11 VanDerWaalsContact O-N 3.16Å; R11-L13 VanDerWaalsContact C-N 3.32Å; R11-E14 PolarHBondContact O-N 3.43Å; R11-L15 WeakPolarHBondContact O-CD1 3.45Å; R11-L15 PolarHBondContact O-N 3.42Å
12	C	39.4	Very low	39.1	Very low	60 Å²	60	132.1 Å²	132.1	41%	0.405	68%	0.677	S	S	.	*	H	α-helix	trans	-68.2	-32	174.4	-69.2	0	0	0	0	112.1	F8 A9 L15	F8-C12 PolarHBondContact O-N 2.86Å; F8-C12 PolarHBondContact O-SG 2.92Å; F8-C12 VanDerWaalsContact O-SG 3.33Å; A9-C12 PolarHBondContact O-N 3.21Å; C12-L15 PolarHBondContact O-N 3.02Å
13	L	40.9	Very low	39.2	Very low	144 Å²	144	131.4 Å²	131.4	75%	0.754	68%	0.683	S	S	*	*	H	α-helix	trans	-70.7	-32.9	174.5	-132	88.1	0	0	0	112.6	A9 R10 R11 L15	A9-L13 PolarHBondContact O-N 2.84Å; R10-L13 PolarHBondContact O-N 2.84Å; R11-L13 VanDerWaalsContact C-N 3.32Å; L13-L15 VanDerWaalsContact C-N 3.31Å
14	E	43.3	Very low	39.1	Very low	148 Å²	148	135.5 Å²	135.5	69%	0.692	70%	0.701	S	S	*	*	H	α-helix	trans	-77.5	-12.3	177.6	-73.3	177.7	-173.3	0	0	113.7	R10 R11 F16	R10-E14 PolarHBondContact O-N 3.37Å; R10-E14 VanDerWaalsContact O-N 3.16Å; R11-E14 PolarHBondContact O-N 3.43Å; E14-F16 VanDerWaalsContact C-N 3.31Å
15	L	39.5	Very low	38.5	Very low	143 Å²	143	133.8 Å²	133.8	75%	0.749	71%	0.706	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.4	-1.5	175.1	-105.8	109.3	0	0	0	114.1	R11 C12 L13 P17	R11-L15 WeakPolarHBondContact O-CD1 3.45Å; R11-L15 PolarHBondContact O-N 3.42Å; C12-L15 PolarHBondContact O-N 3.02Å; L13-L15 VanDerWaalsContact C-N 3.31Å; L15-P17 WeakPolarHBondContact O-CD 3.24Å
16	F	35.4	Very low	37.9	Very low	169 Å²	169	139.3 Å²	139.3	74%	0.741	73%	0.727	S	S	*	*	S	Bend	trans	-93.9	99.6	168.3	-84.1	-87.1	0	0	0	109.6	E14 A18	E14-F16 VanDerWaalsContact C-N 3.31Å; F16-A18 PolarHBondContact O-N 2.97Å; F16-A18 VanDerWaalsContact O-N 3.13Å
17	P	32.7	Very low	36.7	Very low	111 Å²	111	139 Å²	139	72%	0.721	74%	0.741	S	S	*	*			trans	-67.9	114.1	166.6	27.6	-29.9	0	0	0	107.9	L15 R19	L15-P17 WeakPolarHBondContact O-CD 3.24Å; P17-R19 PolarHBondContact O-N 3.36Å
18	A	43.5	Very low	36	Very low	108 Å²	108	138 Å²	138	89%	0.893	75%	0.752	S	S	*	*			trans	-57.7	102.5	162.2	0	0	0	0	0	107.9	F16	F16-A18 PolarHBondContact O-N 2.97Å; F16-A18 VanDerWaalsContact O-N 3.13Å
19	R	32.9	Very low	34.8	Very low	236 Å²	236	136.9 Å²	136.9	89%	0.891	76%	0.763	S	S	*	*			trans	-116	114.8	170.2	-133.8	179.1	-174.5	-173.8	0.5	108.2	P17	P17-R19 PolarHBondContact O-N 3.36Å
20	N	30.8	Very low	34	Very low	153 Å²	153	138 Å²	138	82%	0.818	78%	0.779	S	S	*	*			trans	-50.6	152	173.1	-81.8	-18.2	0	0	0	112	A22	N20-A22 PolarHBondContact O-N 3.22Å
21	P	35.2	Very low	33	Very low	130 Å²	130	133.7 Å²	133.7	84%	0.844	79%	0.789	S	S	*	*			trans	-72.8	124.4	-174.5	30.7	-32.7	0	0	0	109.9
22	A	28	Very low	32	Very low	90 Å²	90	137.3 Å²	137.3	74%	0.744	80%	0.802	S	S	*	*			trans	-107.1	124	160.7	0	0	0	0	0	107.7	N20	N20-A22 PolarHBondContact O-N 3.22Å
23	C	31.2	Very low	31.3	Very low	127 Å²	127	139.6 Å²	139.6	86%	0.858	83%	0.826	S	S	*	*			trans	-46.9	137.1	173.1	-61.4	0	0	0	0	112.2
24	V	28.7	Very low	30.5	Very low	145 Å²	145	140.7 Å²	140.7	88%	0.879	83%	0.829	S	S	*	*			trans	-135.2	123.9	157	-179	0	0	0	0	108.2
25	D	26.3	Very low	29.6	Very low	155 Å²	155	140.2 Å²	140.2	83%	0.829	83%	0.83	S	S	*	*			trans	-63.8	151.6	-172.5	-78.1	-54	0	0	0	115.2
26	F	27.4	Very low	28.8	Very low	209 Å²	209	139.1 Å²	139.1	92%	0.917	83%	0.83	S	S	*	*			trans	-67.3	119.7	168.8	-112.9	-101.6	0	0	0	110.8
27	G	25.6	Very low	28.1	Very low	77 Å²	77	139.5 Å²	139.5	79%	0.794	83%	0.832	S	S	*	*			trans	-111.7	105.5	168.6	0	0	0	0	0	110.8
28	T	28.8	Very low	27.7	Very low	136 Å²	136	143.5 Å²	143.5	83%	0.834	84%	0.843	S	S	*	*			trans	-68.4	132.9	171.2	36.5	0	0	0	0	111.6
29	S	26.3	Very low	26.8	Very low	123 Å²	123	142.3 Å²	142.3	86%	0.86	83%	0.833	S	S	*	*			trans	-158.1	121.7	147.6	-170.8	0	0	0	0	110.7
30	G	25.3	Very low	26.3	Very low	78 Å²	78	136.5 Å²	136.5	80%	0.804	83%	0.829	S	S	*	*			trans	-75.9	165.1	-178.5	0	0	0	0	0	114.5
31	G	25.6	Very low	26.1	Very low	82 Å²	82	136.2 Å²	136.2	85%	0.845	83%	0.827	S	S	*	*			trans	-172.3	84.3	171.5	0	0	0	0	0	110.3
32	R	25.6	Very low	25.7	Very low	259 Å²	259	135.8 Å²	135.8	98%	0.977	83%	0.827	S	S	*	*			trans	-68.6	130.8	165	-101.6	174	160.6	173.3	-6.1	108.9
33	A	24.6	Very low	25.7	Very low	108 Å²	108	141 Å²	141	89%	0.893	84%	0.836	S	S	*	*			trans	-142	134.4	151.4	0	0	0	0	0	109.1
34	M	24.2	Very low	25.5	Very low	168 Å²	168	143.8 Å²	143.8	83%	0.828	84%	0.837	S	S	*	*			trans	-116.7	135.1	-164.9	177.6	178.6	174.8	0	0	108.5
35	L	23.2	Very low	25.5	Very low	138 Å²	138	146 Å²	146	72%	0.723	84%	0.837	S	S	*	*			trans	44.2	134.3	151.9	-75	153.9	0	0	0	120.5
36	T	22.6	Very low	25.4	Very low	120 Å²	120	144.6 Å²	144.6	74%	0.736	83%	0.834	S	S	*	*				172	126.8	100.5	-61.3	0	0	0	0	112.3
37	F	22.2	Very low	25.4	Very low	177 Å²	177	140.2 Å²	140.2	78%	0.776	83%	0.828	S	S	*	*			trans	45.6	124.1	149.8	-94.9	-113.7	0	0	0	123
38	M	23.7	Very low	25.4	Very low	194 Å²	194	143.9 Å²	143.9	96%	0.956	83%	0.83	S	S	*	*				-157.5	135.4	104.9	-87.4	-132.5	135.1	0	0	110.6
39	A	24.1	Very low	25.5	Very low	83 Å²	83	145.1 Å²	145.1	69%	0.686	83%	0.826	S	S	*	*			trans	-104.3	153.2	-175.6	0	0	0	0	0	111.4
40	S	23.3	Very low	25.7	Very low	115 Å²	115	149.8 Å²	149.8	80%	0.804	83%	0.825	S	S	*	*			trans	177.8	95.2	140.4	-151.1	0	0	0	0	107.1
41	D	26.4	Very low	25.9	Very low	147 Å²	147	151.9 Å²	151.9	79%	0.786	82%	0.822	S	S	*	*				68.9	110.4	91.2	-85.3	-6.9	0	0	0	115.1
42	S	26.5	Very low	26	Very low	120 Å²	120	153.8 Å²	153.8	84%	0.839	82%	0.822	S	S	*	*			trans	-170.6	80.8	146	-67.9	0	0	0	0	109.8
43	E	28.6	Very low	26.3	Very low	200 Å²	200	148.8 Å²	148.8	94%	0.935	81%	0.814	S	S	*	*			trans	40.6	111.3	141.8	-55.9	-179.9	129.7	0	0	121
44	E	26.3	Very low	26.5	Very low	186 Å²	186	152.8 Å²	152.8	87%	0.869	82%	0.817	S	S	*	*			trans	-87.5	138.7	156.6	-65.9	177.7	136.9	0	0	109.6
45	E	27.9	Very low	26.6	Very low	190 Å²	190	150.5 Å²	150.5	89%	0.888	82%	0.817	S	S	*	*			trans	-120.4	115.1	155.6	-88.4	-162.8	152.1	0	0	110.8
46	V	24.5	Very low	26.9	Very low	126 Å²	126	149 Å²	149	76%	0.764	82%	0.824	S	S	*	*			trans	-79.8	132.2	167.7	169.3	0	0	0	0	108
47	C	27.4	Very low	27.2	Very low	118 Å²	118	152.4 Å²	152.4	80%	0.797	83%	0.832	S	S	*	*			trans	-129.4	110.3	168	-79.6	0	0	0	0	109.6
48	D	26.8	Very low	27.4	Very low	154 Å²	154	149 Å²	149	82%	0.824	83%	0.83	S	S	*	*			trans	-130.4	143.9	161.8	-113.9	-32	0	0	0	110.9
49	E	29.4	Very low	27.7	Very low	162 Å²	162	145.9 Å²	145.9	76%	0.757	82%	0.824	S	S	*	*			trans	62.9	107.6	165.4	-73.2	-165.9	106.1	0	0	123.9
50	R	31.2	Very low	27.9	Very low	220 Å²	220	148.1 Å²	148.1	83%	0.83	83%	0.83	S	S	*	*				63.5	118.6	113.2	-132.7	-167.6	169.4	122.8	-2	120.5
51	T	29.4	Very low	28.2	Very low	123 Å²	123	148.6 Å²	148.6	76%	0.755	83%	0.83	S	S	*	*			trans	87.4	102.2	146	-16.1	0	0	0	0	119.2
52	S	28.8	Very low	28.2	Very low	121 Å²	121	153.3 Å²	153.3	85%	0.846	84%	0.837	S	S	*	*			trans	-162.4	125.1	137.7	175.9	0	0	0	0	110.7
53	L	30.2	Very low	27.9	Very low	155 Å²	155	153 Å²	153	81%	0.812	84%	0.835	S	S	*	*			trans	-54.5	142.7	176	-76.9	141.8	0	0	0	113.8
54	M	29.9	Very low	27.7	Very low	192 Å²	192	149.9 Å²	149.9	95%	0.946	83%	0.834	S	S	*	*			trans	-162.5	135	134.9	-109.9	175.6	160	0	0	112.3
55	S	26.7	Very low	27.7	Very low	119 Å²	119	150 Å²	150	83%	0.832	83%	0.834	S	S	*	*			trans	-65.3	147.5	-173	-50.5	0	0	0	0	114.7
56	A	29.5	Very low	27.7	Very low	106 Å²	106	150.2 Å²	150.2	88%	0.876	84%	0.835	S	S	*	*			trans	-129.9	112.2	157.4	0	0	0	0	0	109.1
57	E	27.3	Very low	27.8	Very low	193 Å²	193	147.6 Å²	147.6	90%	0.902	83%	0.834	S	S	*	*			trans	-83.9	140.8	-178.8	-163.9	156.8	107.3	0	0	110.4
58	S	26.9	Very low	27.7	Very low	105 Å²	105	153.4 Å²	153.4	73%	0.734	84%	0.839	S	S	*	*			trans	-128.3	155.3	169.6	66	0	0	0	0	109.4
59	P	30.8	Very low	27.6	Very low	128 Å²	128	155.2 Å²	155.2	83%	0.831	84%	0.842	S	S	*	*	P	Polyproline II helix	trans	-89.7	148.4	-131.5	32.5	-35.4	0	0	0	115.9
60	T	28.1	Very low	27.4	Very low	130 Å²	130	151.1 Å²	151.1	80%	0.798	84%	0.844	S	S	*	*	P	Polyproline II helix	trans	-82.7	152.9	171.8	39.8	0	0	0	0	114.1
61	P	30	Very low	27.8	Very low	126 Å²	126	146 Å²	146	82%	0.818	84%	0.839	S	S	*	*	P	Polyproline II helix	trans	-81.7	144.5	-179.3	34.1	-32.6	0	0	0	112
62	R	25.3	Very low	27.8	Very low	245 Å²	245	148.2 Å²	148.2	93%	0.925	84%	0.841	S	S	*	*	P	Polyproline II helix	trans	-93.3	129.2	173.6	-91.7	-173.3	172	174.4	-1.4	111.6
63	S	21.7	Very low	27.8	Very low	114 Å²	114	149.6 Å²	149.6	80%	0.797	84%	0.839	S	S	*	*	P	Polyproline II helix	trans	-72.3	131.8	160.2	54.3	0	0	0	0	111.4
64	C	24.1	Very low	27.6	Very low	134 Å²	134	145.6 Å²	145.6	91%	0.905	84%	0.835	S	S	*	*			trans	-130.1	121.3	156.7	-91	0	0	0	0	107.9
65	Q	26.8	Very low	27.6	Very low	189 Å²	189	144.9 Å²	144.9	88%	0.883	83%	0.829	S	S	*	*			trans	-101.5	119.7	174.7	-177.2	177.8	22.2	0	0	107.4
66	E	26.5	Very low	27.5	Very low	195 Å²	195	145.9 Å²	145.9	91%	0.911	83%	0.825	S	S	*	*			trans	-147.8	114.4	166.3	-156	91.1	-166.5	0	0	110.7
67	G	26	Very low	27.4	Very low	71 Å²	71	148.4 Å²	148.4	73%	0.732	82%	0.822	S	S	*	*			trans	19.7	120.9	156.9	0	0	0	0	0	125.4
68	R	25.5	Very low	27.4	Very low	240 Å²	240	143.1 Å²	143.1	91%	0.906	81%	0.811	S	S	*	*				83.1	109.2	114.2	-149	-176.5	-157.6	-170.1	5.3	120.8
69	Q	25.6	Very low	27.3	Very low	191 Å²	191	145.7 Å²	145.7	89%	0.893	81%	0.812	S	S	*	*				172	131.7	121.5	-92.1	167.9	26.8	0	0	110.5
70	G	24.9	Very low	27	Very low	76 Å²	76	151.7 Å²	151.7	78%	0.784	82%	0.818	S	S	*	*			trans	-95.3	-150	-179	0	0	0	0	0	113.8
71	P	40.3	Very low	26.8	Very low	114 Å²	114	156.2 Å²	156.2	74%	0.74	82%	0.82	S	S	*	*			cis	-129.7	-162.8	-23.1	30.8	-6.8	0	0	0	113.3
72	E	28.6	Very low	26.5	Very low	168 Å²	168	155.1 Å²	155.1	79%	0.785	82%	0.816	S	S	*	*			trans	90.6	131.1	162	-58	179.3	157.6	0	0	115.8
73	D	28.2	Very low	26.5	Very low	151 Å²	151	152.1 Å²	152.1	81%	0.807	81%	0.813	S	S	*	*			cis	-166.6	161	9.5	-87.8	-31.1	0	0	0	110.5
74	G	27.9	Very low	26.7	Very low	70 Å²	70	154.4 Å²	154.4	72%	0.722	81%	0.811	S	S	*	*			trans	103.2	84.2	134.2	0	0	0	0	0	121.9
75	E	28.1	Very low	26.7	Very low	178 Å²	178	156.3 Å²	156.3	83%	0.832	81%	0.812	S	S	*	*				35.8	122	127.2	-77.8	178.4	111.6	0	0	124.4
76	N	24.9	Very low	26.9	Very low	139 Å²	139	155.6 Å²	155.6	74%	0.743	81%	0.809	S	S	*	*				55.2	129.1	111.5	-107.3	-25.9	0	0	0	121.9
77	I	27.1	Very low	27.1	Very low	159 Å²	159	155 Å²	155	82%	0.815	81%	0.805	S	S	*	*				141.8	135	129.4	-74.7	153.2	0	0	0	114.8
78	A	28.1	Very low	27.1	Very low	82 Å²	82	159.1 Å²	159.1	68%	0.678	81%	0.811	S	S	*	*			trans	-72.6	-179.9	-179.1	0	0	0	0	0	115.3
79	Q	24.8	Very low	27.2	Very low	159 Å²	159	151 Å²	151	74%	0.743	80%	0.803	S	S	*	*			trans	91	112.3	139.9	-163.7	173.2	-0.3	0	0	116.6
80	W	24.4	Very low	27.4	Very low	255 Å²	255	151.6 Å²	151.6	97%	0.966	81%	0.805	S	S	*	*				-154.6	135.1	128.3	-82.5	106.8	0	0	0	110.6
81	R	24.5	Very low	27.7	Very low	224 Å²	224	157.5 Å²	157.5	85%	0.845	81%	0.812	S	S	*	*			trans	-119.4	159.9	179.3	-173.9	-176.2	-159.5	144.8	4.8	107.5
82	S	23.6	Very low	27.3	Very low	104 Å²	104	158.6 Å²	158.6	73%	0.727	81%	0.812	S	S	*	*			trans	91.8	136.2	167.6	-49.1	0	0	0	0	113.6
83	Q	24.2	Very low	27.8	Very low	182 Å²	182	155.9 Å²	155.9	85%	0.85	81%	0.809	S	S	*	*			cis	-166.4	156.5	44.8	-163.3	154.7	0.1	0	0	112.4
84	E	26.9	Very low	28	Very low	162 Å²	162	155.4 Å²	155.4	76%	0.757	81%	0.806	S	S	*	*			trans	-67.1	160	-178.5	-66.1	152.4	130.2	0	0	115.2
85	N	23.9	Very low	28.2	Very low	173 Å²	173	162.6 Å²	162.6	93%	0.925	81%	0.811	S	S	*	*			trans	-155.9	119.2	142	-95.3	-21.8	0	0	0	109.3
86	E	31.3	Very low	28.4	Very low	175 Å²	175	164.7 Å²	164.7	82%	0.818	81%	0.813	S	S	*	*			trans	-91.4	144.5	162.6	-76.8	173.2	101.7	0	0	109.2
87	E	29.4	Very low	28.8	Very low	181 Å²	181	162.7 Å²	162.7	85%	0.846	81%	0.806	S	S	*	*				172.3	117.7	128.7	-92.9	178.5	168.9	0	0	111.6
88	D	26.6	Very low	29.1	Very low	158 Å²	158	161 Å²	161	85%	0.845	81%	0.807	S	S	*	*			trans	55.1	116.3	141.6	-61.8	-20.8	0	0	0	124.4
89	G	27.2	Very low	29.4	Very low	71 Å²	71	162.5 Å²	162.5	73%	0.732	81%	0.812	S	S	*	*				100	97.4	113	0	0	0	0	0	119.2
90	E	30.1	Very low	29.8	Very low	203 Å²	203	158.1 Å²	158.1	95%	0.949	81%	0.81	S	S	*	*				-177.1	125	124.7	-101.8	177.8	144.3	0	0	109.4
91	E	32.6	Very low	30.5	Very low	200 Å²	200	151.9 Å²	151.9	94%	0.935	80%	0.8	S	S	*	*			trans	-75.9	123.1	178	-65.2	175.2	146.2	0	0	110.2
92	D	30.6	Very low	31.3	Very low	137 Å²	137	147.5 Å²	147.5	73%	0.733	80%	0.8	S	S	*	*			trans	-117.5	114	167.8	-168.3	10	0	0	0	108.6	D94	D92-D94 PolarHBondContact O-N 3.29Å
93	P	39.9	Very low	32.4	Very low	110 Å²	110	146.4 Å²	146.4	71%	0.714	81%	0.805	S	S	*	*			trans	-91.4	22.3	-169.1	35.9	-34.3	0	0	0	115.1
94	D	32.1	Very low	33.2	Very low	141 Å²	141	143.5 Å²	143.5	75%	0.754	79%	0.786	S	S	*	*			trans	-129.5	41.1	-177.7	-78.4	-36	0	0	0	114.9	D92	D92-D94 PolarHBondContact O-N 3.29Å
95	R	32.2	Very low	34.3	Very low	221 Å²	221	139.5 Å²	139.5	83%	0.834	78%	0.775	S	S	*	*			trans	-110	73.3	165.6	-154.2	171.7	-178.4	170.3	-1.6	111	V97	R95-V97 HydrophobicContact CG-CG2 3.99Å; R95-V97 PolarHBondContact O-N 3.05Å
96	Y	32.2	Very low	35.6	Very low	223 Å²	223	137 Å²	137	88%	0.875	77%	0.767	S	S	*	*			trans	-64.3	85.3	158.9	-94.9	-91.3	0	0	0	108.6	C98	Y96-C98 PolarHBondContact O-N 2.89Å
97	V	32.7	Very low	36.8	Very low	97 Å²	97	130.5 Å²	130.5	59%	0.588	75%	0.748	S	S	*	*			trans	-65.7	108.4	156.9	179.8	0	0	0	0	105.1	R95 S99	R95-V97 HydrophobicContact CG-CG2 3.99Å; R95-V97 PolarHBondContact O-N 3.05Å; V97-S99 VanDerWaalsContact C-N 3.33Å; V97-S99 PolarHBondContact O-N 3.19Å
98	C	34.8	Very low	38	Very low	123 Å²	123	124.9 Å²	124.9	83%	0.831	72%	0.723	S	S	*	*			trans	-53.9	104.8	162	-93.3	0	0	0	0	107.1	Y96 G100	Y96-C98 PolarHBondContact O-N 2.89Å; C98-G100 PolarHBondContact O-N 3.1Å
99	S	33.7	Very low	39.4	Very low	113 Å²	113	122.9 Å²	122.9	79%	0.79	71%	0.709	S	S	*	*			trans	-56.5	114.2	167.8	-71.4	0	0	0	0	107.5	V97 V101	V97-S99 VanDerWaalsContact C-N 3.33Å; V97-S99 PolarHBondContact O-N 3.19Å; S99-V101 PolarHBondContact O-N 3.1Å
100	G	33.8	Very low	41.1	Very low	67 Å²	67	126.1 Å²	126.1	69%	0.691	71%	0.705	S	S	*	*	P	Polyproline II helix	trans	-54.1	132.9	173.7	0	0	0	0	0	110.3	C98	C98-G100 PolarHBondContact O-N 3.1Å
101	V	38	Very low	42.6	Very low	125 Å²	125	122.9 Å²	122.9	76%	0.758	69%	0.69	S	S	*	*	P	Polyproline II helix	trans	-57	126.8	164.1	176.4	0	0	0	0	107.6	S99 G103	S99-V101 PolarHBondContact O-N 3.1Å; V101-G103 PolarHBondContact O-N 3.24Å
102	P	41.2	Very low	43.8	Very low	132 Å²	132	115.5 Å²	115.5	86%	0.857	66%	0.657	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72	116.5	179.3	8.6	1.6	0	0	0	109.1
103	G	46.6	Very low	45.4	Very low	80 Å²	80	113.6 Å²	113.6	83%	0.825	65%	0.65	S	S	*	*	T	Hydrogen-bonded Turn	trans	127.1	3.6	168.6	0	0	0	0	0	117.2	V101	V101-G103 PolarHBondContact O-N 3.24Å
104	R	42.5	Very low	46.8	Very low	121 Å²	121	114.5 Å²	114.5	46%	0.457	65%	0.648	S	S	.	*			trans	-97	123.4	176.1	-163.2	167.4	-119.4	177.1	-2.5	110.6	L108	R104-L108 HydrophobicContact CG-CB 4.35Å; R104-L108 HydrophobicContact CG-CD2 4.3Å
105	P	48.1	Very low	48.6	Very low	79 Å²	79	115.2 Å²	115.2	51%	0.513	65%	0.645	S	S	.	*			trans	-63.5	135.3	176.4	23.4	-29.6	0	0	0	109.4	G107 L108	P105-G107 PolarHBondContact O-N 3.34Å; P105-L108 HydrophobicContact CG-CB 4.23Å; P105-L108 HydrophobicContact CG-CD1 4.49Å; P105-L108 PolarHBondContact O-N 2.92Å
106	P	52.3	Low	50.1	Low	119 Å²	119	108.4 Å²	108.4	77%	0.773	62%	0.619	S	S	*	*	T	Hydrogen-bonded Turn	trans	-61.9	-8	-173	21.3	-31.8	0	0	0	115
107	G	55.5	Low	52	Low	40 Å²	40	99.4 Å²	99.4	41%	0.412	59%	0.594	S	S	.	*	T	Hydrogen-bonded Turn	trans	-86.7	-17.5	174.2	0	0	0	0	0	115.2	P105 E111	P105-G107 PolarHBondContact O-N 3.34Å; G107-E111 WeakPolarHBondContact O-CB 3.42Å; G107-E111 PolarHBondContact O-N 3.36Å
108	L	55.2	Low	54.2	Low	63 Å²	63	97.2 Å²	97.2	33%	0.33	59%	0.586	S	S	.	*	H	α-helix	trans	-77.9	-28.3	-170.9	-163.9	135.4	0	0	0	112.8	R104 P105 L112	R104-L108 HydrophobicContact CG-CB 4.35Å; R104-L108 HydrophobicContact CG-CD2 4.3Å; P105-L108 HydrophobicContact CG-CB 4.23Å; P105-L108 HydrophobicContact CG-CD1 4.49Å; P105-L108 PolarHBondContact O-N 2.92Å; L108-L112 HydrophobicContact CD2-CD1 3.56Å; L108-L112 HydrophobicContact CD2-CG 4.32Å; L108-L112 HydrophobicContact CG-CD1 4.49Å; L108-L112 VanDerWaalsContact O-CB 3.31Å; L108-L112 WeakPolarHBondContact O-CB 3.27Å; L108-L112 WeakPolarHBondContact O-CD1 3.38Å; L108-L112 WeakPolarHBondContact O-CG 3.25Å; L108-L112 PolarHBondContact O-N 3.22Å
109	E	56.7	Low	56.2	Low	116 Å²	116	95.5 Å²	95.5	54%	0.542	57%	0.565	S	S	.	*	H	α-helix	trans	-74.2	-39.1	175	-65.3	-177.5	172.4	0	0	111.8	L112 T113	E109-L112 PolarHBondContact O-N 2.83Å; E109-T113 VanDerWaalsContact O-CG2 3.31Å; E109-T113 WeakPolarHBondContact O-CG2 3.27Å; E109-T113 PolarHBondContact O-N 3.46Å; E109-T113 PolarHBondContact O-OG1 3.28Å; E109-T113 VanDerWaalsContact O-OG1 3.05Å
110	E	62.2	Low	58.1	Low	138 Å²	138	92 Å²	92	65%	0.645	54%	0.536	S	S	*	.	H	α-helix	trans	-66.2	-40.3	172	-68.3	-174.1	165.8	0	0	111.6	T113 L114	E110-T113 WeakPolarHBondContact CA-OG1 3.18Å; E110-T113 PolarHBondContact O-N 3.49Å; E110-T113 PolarHBondContact O-OG1 3Å; E110-L114 WeakPolarHBondContact O-CB 3.13Å; E110-L114 PolarHBondContact O-N 2.94Å; E110-L114 VanDerWaalsContact O-N 3.08Å
111	E	61.4	Low	60.4	Low	136 Å²	136	90.7 Å²	90.7	64%	0.636	52%	0.515	S	S	*	.	H	α-helix	trans	-66.7	-38.3	177	-165.4	178.4	174.5	0	0	112.2	G107 K115	G107-E111 WeakPolarHBondContact O-CB 3.42Å; G107-E111 PolarHBondContact O-N 3.36Å; E111-K115 VanDerWaalsContact O-CB 3.31Å; E111-K115 WeakPolarHBondContact O-CB 3.35Å; E111-K115 PolarHBondContact O-N 3.34Å
112	L	57.7	Low	62.5	Low	45 Å²	45	89.8 Å²	89.8	24%	0.236	50%	0.504	C	S	.	.	H	α-helix	trans	-65.2	-50	174.4	-80.7	166.1	0	0	0	111.5	L108 E109 L114 K115 Y116	L108-L112 HydrophobicContact CD2-CD1 3.56Å; L108-L112 HydrophobicContact CD2-CG 4.32Å; L108-L112 HydrophobicContact CG-CD1 4.49Å; L108-L112 VanDerWaalsContact O-CB 3.31Å; L108-L112 WeakPolarHBondContact O-CB 3.27Å; L108-L112 WeakPolarHBondContact O-CD1 3.38Å; L108-L112 WeakPolarHBondContact O-CG 3.25Å; L108-L112 PolarHBondContact O-N 3.22Å; E109-L112 PolarHBondContact O-N 2.83Å; L112-L114 VanDerWaalsContact C-N 3.3Å; L112-L114 PolarHBondContact O-N 2.78Å; L112-K115 PolarHBondContact O-N 2.83Å; L112-K115 VanDerWaalsContact O-N 3.1Å; L112-Y116 VanDerWaalsContact C-CD2 3.49Å; L112-Y116 HydrophobicContact CB-CD2 4.2Å; L112-Y116 HydrophobicContact CB-CE2 3.83Å; L112-Y116 HydrophobicContact CD2-CE2 3.63Å; L112-Y116 HydrophobicContact CG-CE2 4.3Å; L112-Y116 WeakPolarHBondContact O-CD2 3.3Å; L112-Y116 PolarHBondContact O-N 3.33Å
113	T	65.4	Low	64.6	Low	96 Å²	96	86.8 Å²	86.8	59%	0.589	48%	0.48	S	S	*	.	H	α-helix	trans	-60.4	-37.7	179.4	52.6	0	0	0	0	112.7	E109 E110 G117	E109-T113 VanDerWaalsContact O-CG2 3.31Å; E109-T113 WeakPolarHBondContact O-CG2 3.27Å; E109-T113 PolarHBondContact O-N 3.46Å; E109-T113 PolarHBondContact O-OG1 3.28Å; E109-T113 VanDerWaalsContact O-OG1 3.05Å; E110-T113 WeakPolarHBondContact CA-OG1 3.18Å; E110-T113 PolarHBondContact O-N 3.49Å; E110-T113 PolarHBondContact O-OG1 3Å; T113-G117 PolarHBondContact O-N 3.49Å
114	L	67.8	Low	66.4	Low	130 Å²	130	83 Å²	83	68%	0.681	44%	0.441	S	S	*	.	H	α-helix	trans	-65.2	-44.4	171.9	-91.7	158.1	0	0	0	112.7	E110 L112 G117 A118	E110-L114 WeakPolarHBondContact O-CB 3.13Å; E110-L114 PolarHBondContact O-N 2.94Å; E110-L114 VanDerWaalsContact O-N 3.08Å; L112-L114 VanDerWaalsContact C-N 3.3Å; L112-L114 PolarHBondContact O-N 2.78Å; L114-G117 PolarHBondContact O-N 3.03Å; L114-A118 WeakPolarHBondContact O-CB 3.33Å; L114-A118 PolarHBondContact O-N 3.46Å
115	K	69.8	Low	68.6	Low	156 Å²	156	78.9 Å²	78.9	68%	0.678	43%	0.426	S	S	*	.	H	α-helix	trans	-66	-40.8	-179.5	-168.4	174.5	-178.7	-177.8	0	112	E111 L112 A118 K119	E111-K115 VanDerWaalsContact O-CB 3.31Å; E111-K115 WeakPolarHBondContact O-CB 3.35Å; E111-K115 PolarHBondContact O-N 3.34Å; L112-K115 PolarHBondContact O-N 2.83Å; L112-K115 VanDerWaalsContact O-N 3.1Å; K115-A118 PolarHBondContact O-N 3.15Å; K115-K119 WeakPolarHBondContact O-CB 3.37Å; K115-K119 PolarHBondContact O-N 2.91Å
116	Y	64.8	Low	70.7	Confident	77 Å²	77	79 Å²	79	30%	0.302	43%	0.425	S	S	.	.	H	α-helix	trans	-66.9	-43.8	174	-66.6	-60.6	0	0	0	111.4	L112 A118 K119 H120 E389	L112-Y116 VanDerWaalsContact C-CD2 3.49Å; L112-Y116 HydrophobicContact CB-CD2 4.2Å; L112-Y116 HydrophobicContact CB-CE2 3.83Å; L112-Y116 HydrophobicContact CD2-CE2 3.63Å; L112-Y116 HydrophobicContact CG-CE2 4.3Å; L112-Y116 WeakPolarHBondContact O-CD2 3.3Å; L112-Y116 PolarHBondContact O-N 3.33Å; Y116-A118 VanDerWaalsContact C-N 3.32Å; Y116-A118 PolarHBondContact O-N 2.86Å; Y116-K119 PolarHBondContact O-N 2.87Å; Y116-H120 PolarHBondContact O-CD2 3.33Å; Y116-H120 PolarHBondContact O-N 3.48Å; Y116-E389 HydrophobicContact CE1-CG 4.47Å
117	G	72.3	Confident	72.5	Confident	34 Å²	34	73.6 Å²	73.6	35%	0.351	39%	0.39	S	S	.	.	H	α-helix	trans	-54.1	-47.8	173	0	0	0	0	0	112.2	T113 L114 H120 V121	T113-G117 PolarHBondContact O-N 3.49Å; L114-G117 PolarHBondContact O-N 3.03Å; G117-H120 PolarHBondContact O-N 2.99Å; G117-V121 WeakPolarHBondContact O-CB 3.08Å; G117-V121 WeakPolarHBondContact O-CG2 3.14Å; G117-V121 PolarHBondContact O-N 3.2Å
118	A	77.8	Confident	74.3	Confident	51 Å²	51	71.8 Å²	71.8	42%	0.421	37%	0.371	S	S	.	.	H	α-helix	trans	-64.5	-42.5	178	0	0	0	0	0	113	L114 K115 Y116 V121 I122	L114-A118 WeakPolarHBondContact O-CB 3.33Å; L114-A118 PolarHBondContact O-N 3.46Å; K115-A118 PolarHBondContact O-N 3.15Å; Y116-A118 VanDerWaalsContact C-N 3.32Å; Y116-A118 PolarHBondContact O-N 2.86Å; A118-V121 PolarHBondContact O-N 2.93Å; A118-I122 VanDerWaalsContact O-CG1 3.3Å; A118-I122 WeakPolarHBondContact O-CG1 3.17Å; A118-I122 PolarHBondContact O-N 2.91Å
119	K	76.9	Confident	76.2	Confident	88 Å²	88	70.1 Å²	70.1	38%	0.383	36%	0.364	S	S	.	.	H	α-helix	trans	-60.6	-45.8	176.2	-175.1	179.2	174.3	-176.5	0	111.1	K115 Y116 I122 M123 E389	K115-K119 WeakPolarHBondContact O-CB 3.37Å; K115-K119 PolarHBondContact O-N 2.91Å; Y116-K119 PolarHBondContact O-N 2.87Å; K119-I122 PolarHBondContact O-N 3.24Å; K119-M123 HydrophobicContact CD-CE 4.32Å; K119-M123 HydrophobicContact CG-CE 3.98Å; K119-M123 HydrophobicContact CG-SD 4.39Å; K119-M123 VanDerWaalsContact O-CG 3.3Å; K119-M123 WeakPolarHBondContact O-CG 3.35Å; K119-M123 PolarHBondContact O-N 3.28Å; K119-E389 IonicContact NZ-OE1 3.55Å; K119-E389 PolarHBondContact NZ-OE1 3.48Å
120	H	74.3	Confident	78	Confident	38 Å²	38	68.6 Å²	68.6	18%	0.176	36%	0.359	C	S	.	.	H	α-helix	trans	-64.2	-39.5	176.7	-71.8	-60.5	0	0	0	112.7	Y116 G117 M123 L124 V393	Y116-H120 PolarHBondContact O-CD2 3.33Å; Y116-H120 PolarHBondContact O-N 3.48Å; G117-H120 PolarHBondContact O-N 2.99Å; H120-M123 PolarHBondContact O-N 2.81Å; H120-L124 PolarHBondContact O-N 2.82Å; H120-V393 HydrophobicContact CB-CG2 4.11Å
121	V	81.4	Confident	79.7	Confident	40 Å²	40	62 Å²	62	24%	0.242	33%	0.328	C	S	.	.	H	α-helix	trans	-60.6	-50.6	174.7	173	0	0	0	0	109.9	G117 A118 M123 L124 F125 L436	G117-V121 WeakPolarHBondContact O-CB 3.08Å; G117-V121 WeakPolarHBondContact O-CG2 3.14Å; G117-V121 PolarHBondContact O-N 3.2Å; A118-V121 PolarHBondContact O-N 2.93Å; V121-M123 VanDerWaalsContact C-N 3.32Å; V121-M123 PolarHBondContact O-N 3.41Å; V121-L124 PolarHBondContact O-N 3.25Å; V121-F125 HydrophobicContact CG1-CD2 3.69Å; V121-F125 HydrophobicContact CG1-CE2 3.54Å; V121-F125 HydrophobicContact CG1-CZ 4.34Å; V121-F125 WeakPolarHBondContact O-CD2 3.49Å; V121-F125 PolarHBondContact O-N 2.99Å; V121-L436 HydrophobicContact CB-CD1 4.13Å; V121-L436 HydrophobicContact CG1-CD1 4.03Å; V121-L436 HydrophobicContact CG2-CD1 3.67Å
122	I	83.5	Confident	81.3	Confident	106 Å²	106	55.6 Å²	55.6	54%	0.544	30%	0.298	S	S	.	.	H	α-helix	trans	-60.5	-41.9	-179.5	-67.3	166.1	0	0	0	111.2	A118 K119 L124 F125 V126	A118-I122 VanDerWaalsContact O-CG1 3.3Å; A118-I122 WeakPolarHBondContact O-CG1 3.17Å; A118-I122 PolarHBondContact O-N 2.91Å; K119-I122 PolarHBondContact O-N 3.24Å; I122-L124 PolarHBondContact O-N 2.92Å; I122-F125 PolarHBondContact O-N 3.44Å; I122-F125 VanDerWaalsContact O-N 3.11Å; I122-V126 HydrophobicContact CG2-CG2 4.08Å; I122-V126 WeakPolarHBondContact O-CG2 3.45Å; I122-V126 PolarHBondContact O-N 2.87Å
123	M	83.5	Confident	83.1	Confident	69 Å²	69	58.2 Å²	58.2	34%	0.34	31%	0.311	S	S	.	.	H	α-helix	trans	-60.9	-24.2	177.1	-75.2	178.7	170.8	0	0	113.9	K119 H120 V121 P127	K119-M123 HydrophobicContact CD-CE 4.32Å; K119-M123 HydrophobicContact CG-CE 3.98Å; K119-M123 HydrophobicContact CG-SD 4.39Å; K119-M123 VanDerWaalsContact O-CG 3.3Å; K119-M123 WeakPolarHBondContact O-CG 3.35Å; K119-M123 PolarHBondContact O-N 3.28Å; H120-M123 PolarHBondContact O-N 2.81Å; V121-M123 VanDerWaalsContact C-N 3.32Å; V121-M123 PolarHBondContact O-N 3.41Å; M123-P127 WeakPolarHBondContact O-CD 3.48Å; M123-P127 WeakPolarHBondContact O-CG 3.38Å
124	L	84.3	Confident	84.6	Confident	1 Å²	1	55.3 Å²	55.3	1%	0.005	29%	0.293	C	S	.	.	H	α-helix	trans	-87.9	-35.4	172.4	-67.5	178.5	0	0	0	112.8	H120 V121 I122 P127 V128 V393 L395 L436	H120-L124 PolarHBondContact O-N 2.82Å; V121-L124 PolarHBondContact O-N 3.25Å; I122-L124 PolarHBondContact O-N 2.92Å; L124-P127 WeakPolarHBondContact O-CD 3.47Å; L124-P127 WeakPolarHBondContact O-CG 3.31Å; L124-V128 VanDerWaalsContact O-CG2 3.23Å; L124-V128 WeakPolarHBondContact O-CG2 3.35Å; L124-V393 HydrophobicContact CD1-CB 3.91Å; L124-V393 HydrophobicContact CD1-CG1 3.48Å; L124-V393 VanDerWaalsContact CD1-CG1 3.48Å; L124-V393 HydrophobicContact CD2-CB 4.28Å; L124-V393 HydrophobicContact CD2-CG1 4.23Å; L124-V393 HydrophobicContact CG-CB 4.32Å; L124-V393 HydrophobicContact CG-CG1 4.3Å; L124-L395 HydrophobicContact CD2-CB 4.13Å; L124-L436 HydrophobicContact CD1-CD1 4.07Å; L124-L436 HydrophobicContact CD1-CD2 3.87Å
125	F	89.4	Confident	86	Confident	35 Å²	35	49.1 Å²	49.1	15%	0.154	26%	0.261	C	S	.	.	H	α-helix	trans	-68.6	-44.6	-177.6	-89.5	-120.9	0	0	0	112.6	V121 I122 V128 T129 L429 L432 C433 L436	V121-F125 HydrophobicContact CG1-CD2 3.69Å; V121-F125 HydrophobicContact CG1-CE2 3.54Å; V121-F125 HydrophobicContact CG1-CZ 4.34Å; V121-F125 WeakPolarHBondContact O-CD2 3.49Å; V121-F125 PolarHBondContact O-N 2.99Å; I122-F125 PolarHBondContact O-N 3.44Å; I122-F125 VanDerWaalsContact O-N 3.11Å; F125-V128 PolarHBondContact O-N 3.3Å; F125-T129 WeakPolarHBondContact O-CB 3.35Å; F125-T129 VanDerWaalsContact O-CG2 3.28Å; F125-T129 WeakPolarHBondContact O-CG2 3.42Å; F125-T129 PolarHBondContact O-N 2.85Å; F125-T129 PolarHBondContact O-OG1 3.05Å; F125-L429 HydrophobicContact CD1-CD2 3.79Å; F125-L429 HydrophobicContact CE1-CB 3.85Å; F125-L429 HydrophobicContact CE1-CD2 3.84Å; F125-L429 HydrophobicContact CE1-CG 4.29Å; F125-L429 VanDerWaalsContact CZ-O 3.28Å; F125-L429 WeakPolarHBondContact CZ-O 3.49Å; F125-L432 HydrophobicContact CD2-CD2 3.88Å; F125-L432 HydrophobicContact CE2-CB 4.23Å; F125-L432 HydrophobicContact CE2-CD2 3.31Å; F125-L432 HydrophobicContact CE2-CG 4.24Å; F125-L432 HydrophobicContact CZ-CB 4.12Å; F125-L432 HydrophobicContact CZ-CD2 4.08Å; F125-C433 HydrophobicContact CZ-CB 4.15Å; F125-C433 WeakPolarHBondContact CZ-SG 3.27Å; F125-L436 HydrophobicContact CE2-CD1 4.23Å
126	V	91.5	Very high	87.2	Confident	82 Å²	82	42.4 Å²	42.4	50%	0.497	23%	0.233	S	C	.	.	H	α-helix	trans	-55.4	-53.5	-178.2	173	0	0	0	0	112.9	I122 V128 T129 L130	I122-V126 HydrophobicContact CG2-CG2 4.08Å; I122-V126 WeakPolarHBondContact O-CG2 3.45Å; I122-V126 PolarHBondContact O-N 2.87Å; V126-V128 PolarHBondContact O-N 2.82Å; V126-T129 WeakPolarHBondContact CA-OG1 3.45Å; V126-T129 PolarHBondContact O-N 3.08Å; V126-T129 PolarHBondContact O-OG1 3.09Å; V126-L130 WeakPolarHBondContact O-CB 3.39Å; V126-L130 PolarHBondContact O-N 2.91Å
127	P	91.8	Very high	88.6	Confident	5 Å²	5	41.2 Å²	41.2	3%	0.032	24%	0.239	C	C	.	.	H	α-helix	trans	-68.9	-33.6	-178.5	30.6	-40.1	0	0	0	112.6	M123 L124 C131 I266 Y327 F400	M123-P127 WeakPolarHBondContact O-CD 3.48Å; M123-P127 WeakPolarHBondContact O-CG 3.38Å; L124-P127 WeakPolarHBondContact O-CD 3.47Å; L124-P127 WeakPolarHBondContact O-CG 3.31Å; P127-C131 WeakPolarHBondContact O-CB 3.23Å; P127-C131 PolarHBondContact O-N 3.33Å; P127-I266 HydrophobicContact CB-CD1 3.65Å; P127-I266 HydrophobicContact CB-CG1 4.06Å; P127-Y327 HydrophobicContact CB-CE1 4.25Å; P127-Y327 HydrophobicContact CB-CE2 3.98Å; P127-Y327 WeakPolarHBondContact CB-OH 3.45Å; P127-Y327 HydrophobicContact CG-CE1 3.74Å; P127-Y327 HydrophobicContact CG-CE2 4.38Å; P127-Y327 WeakPolarHBondContact CG-OH 3.39Å; P127-F400 HydrophobicContact CB-CE1 3.89Å; P127-F400 HydrophobicContact CB-CZ 4.37Å; P127-F400 HydrophobicContact CG-CE1 4.18Å; P127-F400 HydrophobicContact CG-CZ 4.28Å
128	V	92.9	Very high	89.7	Confident	1 Å²	1	39.8 Å²	39.8	1%	0.006	22%	0.223	C	C	.	.	H	α-helix	trans	-67.8	-45.5	177.7	171.6	0	0	0	0	110.8	L124 F125 V126 C131 M132 L395 F400 Y403 L432	L124-V128 VanDerWaalsContact O-CG2 3.23Å; L124-V128 WeakPolarHBondContact O-CG2 3.35Å; F125-V128 PolarHBondContact O-N 3.3Å; V126-V128 PolarHBondContact O-N 2.82Å; V128-C131 WeakPolarHBondContact O-CB 3.22Å; V128-C131 PolarHBondContact O-N 3.39Å; V128-M132 HydrophobicContact CG1-CE 3.79Å; V128-M132 WeakPolarHBondContact O-CG 3.25Å; V128-M132 PolarHBondContact O-N 2.94Å; V128-L395 HydrophobicContact CG2-CD2 4.04Å; V128-F400 HydrophobicContact CB-CE1 4.27Å; V128-F400 HydrophobicContact CG2-CD1 3.85Å; V128-F400 HydrophobicContact CG2-CE1 3.45Å; V128-F400 VanDerWaalsContact CG2-CE1 3.45Å; V128-F400 HydrophobicContact CG2-CE2 4.22Å; V128-F400 HydrophobicContact CG2-CG 4.38Å; V128-F400 HydrophobicContact CG2-CZ 3.66Å; V128-Y403 HydrophobicContact CG1-CD2 3.82Å; V128-Y403 HydrophobicContact CG1-CE2 4.48Å; V128-L432 HydrophobicContact CG1-CD1 4.33Å; V128-L432 HydrophobicContact CG2-CD1 4.35Å
129	T	94.7	Very high	90.5	Very high	29 Å²	29	37.6 Å²	37.6	18%	0.178	21%	0.205	C	C	.	.	H	α-helix	trans	-63.4	-43.7	175.9	51.3	0	0	0	0	111.9	F125 V126 C131 M132 I133 F425 L429	F125-T129 WeakPolarHBondContact O-CB 3.35Å; F125-T129 VanDerWaalsContact O-CG2 3.28Å; F125-T129 WeakPolarHBondContact O-CG2 3.42Å; F125-T129 PolarHBondContact O-N 2.85Å; F125-T129 PolarHBondContact O-OG1 3.05Å; V126-T129 WeakPolarHBondContact CA-OG1 3.45Å; V126-T129 PolarHBondContact O-N 3.08Å; V126-T129 PolarHBondContact O-OG1 3.09Å; T129-C131 VanDerWaalsContact C-N 3.34Å; T129-C131 PolarHBondContact O-N 3.39Å; T129-M132 HydrophobicContact CG2-CE 4.25Å; T129-M132 PolarHBondContact O-N 3.19Å; T129-I133 VanDerWaalsContact O-CG1 3.25Å; T129-I133 WeakPolarHBondContact O-CG1 3.4Å; T129-I133 PolarHBondContact O-N 2.96Å; T129-F425 HydrophobicContact CG2-CE2 4.13Å; T129-F425 HydrophobicContact CG2-CZ 3.67Å; T129-L429 HydrophobicContact CG2-CD1 3.9Å; T129-L429 HydrophobicContact CG2-CD2 3.64Å; T129-L429 HydrophobicContact CG2-CG 4.36Å
130	L	95.3	Very high	91.2	Very high	84 Å²	84	36.5 Å²	36.5	44%	0.44	20%	0.2	S	C	.	.	H	α-helix	trans	-59.2	-45.5	176.1	-163.1	156.4	0	0	0	111.2	V126 M132 I133 V134 I266	V126-L130 WeakPolarHBondContact O-CB 3.39Å; V126-L130 PolarHBondContact O-N 2.91Å; L130-M132 PolarHBondContact O-N 2.89Å; L130-I133 PolarHBondContact O-N 2.71Å; L130-V134 HydrophobicContact CD2-CG2 3.91Å; L130-V134 WeakPolarHBondContact O-CG2 3.13Å; L130-V134 PolarHBondContact O-N 3.06Å; L130-I266 HydrophobicContact CD2-CG2 3.69Å
131	C	96	Very high	92.1	Very high	0 Å²	0	36.7 Å²	36.7	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-57	-49.1	175.6	-171.3	0	0	0	0	112.2	P127 V128 T129 I133 V134 V135 I266 S269 F400 S404	P127-C131 WeakPolarHBondContact O-CB 3.23Å; P127-C131 PolarHBondContact O-N 3.33Å; V128-C131 WeakPolarHBondContact O-CB 3.22Å; V128-C131 PolarHBondContact O-N 3.39Å; T129-C131 VanDerWaalsContact C-N 3.34Å; T129-C131 PolarHBondContact O-N 3.39Å; C131-I133 PolarHBondContact O-N 3.42Å; C131-V134 PolarHBondContact O-N 2.87Å; C131-V135 WeakPolarHBondContact O-CG2 3.35Å; C131-V135 PolarHBondContact O-N 3.5Å; C131-V135 VanDerWaalsContact O-N 3.12Å; C131-I266 HydrophobicContact CB-CG2 3.76Å; C131-S269 PolarHBondContact SG-OG 3.28Å; C131-F400 HydrophobicContact CB-CD1 4.19Å; C131-S404 PolarHBondContact SG-OG 3.35Å
132	M	95.8	Very high	92.6	Very high	0 Å²	0	34.8 Å²	34.8	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-61.9	-42.3	178.5	-72.1	-172.2	-68.1	0	0	111.9	V128 T129 L130 V135 V136 V407 F425 I428 L429	V128-M132 HydrophobicContact CG1-CE 3.79Å; V128-M132 WeakPolarHBondContact O-CG 3.25Å; V128-M132 PolarHBondContact O-N 2.94Å; T129-M132 HydrophobicContact CG2-CE 4.25Å; T129-M132 PolarHBondContact O-N 3.19Å; L130-M132 PolarHBondContact O-N 2.89Å; M132-V135 PolarHBondContact O-N 3.39Å; M132-V136 VanDerWaalsContact O-CG2 3.31Å; M132-V136 WeakPolarHBondContact O-CG2 3.37Å; M132-V136 PolarHBondContact O-N 3.43Å; M132-V407 HydrophobicContact CB-CG1 3.98Å; M132-V407 HydrophobicContact CG-CG1 3.87Å; M132-V407 HydrophobicContact SD-CG1 4.23Å; M132-F425 HydrophobicContact CB-CD2 4.17Å; M132-F425 HydrophobicContact CB-CE2 4.16Å; M132-F425 HydrophobicContact CE-CD2 3.71Å; M132-F425 HydrophobicContact CE-CE2 3.59Å; M132-F425 HydrophobicContact CE-CZ 4.42Å; M132-F425 HydrophobicContact SD-CD2 4.05Å; M132-F425 HydrophobicContact SD-CE2 4.44Å; M132-I428 HydrophobicContact SD-CD1 4.03Å; M132-I428 HydrophobicContact SD-CG2 4.21Å; M132-L429 HydrophobicContact CE-CD2 3.97Å; M132-L429 HydrophobicContact CE-CG 4.49Å
133	I	96.4	Very high	92.8	Very high	101 Å²	101	39.7 Å²	39.7	52%	0.518	21%	0.205	S	C	.	.	H	α-helix	trans	-61.5	-46.9	177.6	-70.3	164.8	0	0	0	110.8	T129 L130 C131 V135 V136 A137	T129-I133 VanDerWaalsContact O-CG1 3.25Å; T129-I133 WeakPolarHBondContact O-CG1 3.4Å; T129-I133 PolarHBondContact O-N 2.96Å; L130-I133 PolarHBondContact O-N 2.71Å; C131-I133 PolarHBondContact O-N 3.42Å; I133-V135 VanDerWaalsContact C-N 3.29Å; I133-V135 PolarHBondContact O-N 2.98Å; I133-V136 PolarHBondContact O-N 3.39Å; I133-A137 WeakPolarHBondContact O-CB 3.23Å; I133-A137 PolarHBondContact O-N 2.93Å
134	V	96.7	Very high	93.2	Very high	35 Å²	35	38.5 Å²	38.5	21%	0.212	20%	0.199	C	C	.	.	H	α-helix	trans	-58	-43.1	177.9	169.8	0	0	0	0	111.2	L130 C131 T138 M267 A270	L130-V134 HydrophobicContact CD2-CG2 3.91Å; L130-V134 WeakPolarHBondContact O-CG2 3.13Å; L130-V134 PolarHBondContact O-N 3.06Å; C131-V134 PolarHBondContact O-N 2.87Å; V134-T138 WeakPolarHBondContact O-CB 3.3Å; V134-T138 PolarHBondContact O-N 2.88Å; V134-T138 PolarHBondContact O-OG1 2.96Å; V134-M267 HydrophobicContact CG1-SD 4.43Å; V134-A270 HydrophobicContact CB-CB 4.46Å; V134-A270 HydrophobicContact CG1-CB 3.91Å
135	V	96.9	Very high	93.4	Very high	0 Å²	0	39.2 Å²	39.2	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-69.1	-47.7	179.6	172.2	0	0	0	0	111.4	C131 M132 I133 A137 T138 I139 A270 A273 L274 I277	C131-V135 WeakPolarHBondContact O-CG2 3.35Å; C131-V135 PolarHBondContact O-N 3.5Å; C131-V135 VanDerWaalsContact O-N 3.12Å; M132-V135 PolarHBondContact O-N 3.39Å; I133-V135 VanDerWaalsContact C-N 3.29Å; I133-V135 PolarHBondContact O-N 2.98Å; V135-A137 PolarHBondContact O-N 3.05Å; V135-T138 PolarHBondContact O-N 3Å; V135-I139 HydrophobicContact CG1-CG1 4.35Å; V135-I139 VanDerWaalsContact O-CG1 3.31Å; V135-I139 WeakPolarHBondContact O-CG1 3.47Å; V135-I139 PolarHBondContact O-N 3.46Å; V135-A270 HydrophobicContact CG2-CB 3.64Å; V135-A273 HydrophobicContact CG2-CB 4.12Å; V135-L274 HydrophobicContact CG1-CD2 4.22Å; V135-L274 HydrophobicContact CG2-CG 4.48Å; V135-I277 HydrophobicContact CG1-CD1 3.69Å
136	V	95.3	Very high	93.4	Very high	14 Å²	14	40.4 Å²	40.4	9%	0.085	21%	0.212	C	C	.	.	H	α-helix	trans	-61.1	-46.5	177.8	172.2	0	0	0	0	111.1	M132 I133 T138 I139 K140 V407 A411 W418 T421	M132-V136 VanDerWaalsContact O-CG2 3.31Å; M132-V136 WeakPolarHBondContact O-CG2 3.37Å; M132-V136 PolarHBondContact O-N 3.43Å; I133-V136 PolarHBondContact O-N 3.39Å; V136-T138 VanDerWaalsContact C-N 3.3Å; V136-T138 PolarHBondContact O-N 3.39Å; V136-I139 PolarHBondContact O-N 3.4Å; V136-K140 HydrophobicContact CG1-CG 4.41Å; V136-K140 WeakPolarHBondContact O-CG 3.49Å; V136-K140 PolarHBondContact O-N 3.04Å; V136-V407 HydrophobicContact CG2-CB 4.42Å; V136-V407 HydrophobicContact CG2-CG1 3.99Å; V136-V407 HydrophobicContact CG2-CG2 3.7Å; V136-A411 HydrophobicContact CG1-CB 4.23Å; V136-A411 HydrophobicContact CG2-CB 4.41Å; V136-W418 HydrophobicContact CG1-CZ3 4.09Å; V136-T421 HydrophobicContact CG1-CG2 4Å; V136-T421 HydrophobicContact CG2-CG2 3.9Å
137	A	94.8	Very high	93.1	Very high	52 Å²	52	42 Å²	42	43%	0.43	21%	0.214	S	C	.	.	H	α-helix	trans	-57.9	-44.2	177.3	0	0	0	0	0	111.2	I133 V135 K140 S141	I133-A137 WeakPolarHBondContact O-CB 3.23Å; I133-A137 PolarHBondContact O-N 2.93Å; V135-A137 PolarHBondContact O-N 3.05Å; A137-K140 PolarHBondContact O-N 3.38Å; A137-S141 WeakPolarHBondContact O-CB 3.46Å; A137-S141 PolarHBondContact O-N 3.27Å; A137-S141 PolarHBondContact O-OG 2.94Å
138	T	95.3	Very high	92.3	Very high	5 Å²	5	48.6 Å²	48.6	3%	0.031	24%	0.242	C	C	.	.	H	α-helix	trans	-64.9	-45	177.2	-60	0	0	0	0	112.3	V134 V135 V136 K140 S141 V142 Y145 Y220 L274	V134-T138 WeakPolarHBondContact O-CB 3.3Å; V134-T138 PolarHBondContact O-N 2.88Å; V134-T138 PolarHBondContact O-OG1 2.96Å; V135-T138 PolarHBondContact O-N 3Å; V136-T138 VanDerWaalsContact C-N 3.3Å; V136-T138 PolarHBondContact O-N 3.39Å; T138-K140 VanDerWaalsContact C-N 3.25Å; T138-K140 PolarHBondContact O-N 3.12Å; T138-S141 PolarHBondContact O-N 3.43Å; T138-S141 PolarHBondContact O-OG 2.9Å; T138-V142 HydrophobicContact CG2-CB 4.35Å; T138-V142 HydrophobicContact CG2-CG2 4.31Å; T138-V142 WeakPolarHBondContact O-CB 3.2Å; T138-V142 PolarHBondContact O-N 3.25Å; T138-Y145 HydrophobicContact CG2-CD2 3.89Å; T138-Y145 HydrophobicContact CG2-CE2 3.81Å; T138-Y220 HydrophobicContact CG2-CD2 4.35Å; T138-Y220 HydrophobicContact CG2-CE2 3.63Å; T138-Y220 PolarHBondContact OG1-OH 3.17Å; T138-L274 HydrophobicContact CG2-CD1 3.73Å; T138-L274 HydrophobicContact CG2-CD2 3.7Å; T138-L274 HydrophobicContact CG2-CG 4.39Å
139	I	93.9	Very high	90.8	Very high	5 Å²	5	52.6 Å²	52.6	3%	0.026	26%	0.263	C	S	.	.	H	α-helix	trans	-62	-36.5	179.1	-70.1	-57.6	0	0	0	111.3	V135 V136 Y145 T146 L274 I277 A411 A412	V135-I139 HydrophobicContact CG1-CG1 4.35Å; V135-I139 VanDerWaalsContact O-CG1 3.31Å; V135-I139 WeakPolarHBondContact O-CG1 3.47Å; V135-I139 PolarHBondContact O-N 3.46Å; V136-I139 PolarHBondContact O-N 3.4Å; I139-Y145 HydrophobicContact CD1-CG 4.29Å; I139-T146 HydrophobicContact CG2-CG2 4Å; I139-L274 HydrophobicContact CD1-CD2 3.69Å; I139-L274 HydrophobicContact CG1-CD2 4.05Å; I139-I277 HydrophobicContact CD1-CB 4.27Å; I139-I277 HydrophobicContact CD1-CD1 4.01Å; I139-I277 HydrophobicContact CD1-CG2 3.59Å; I139-I277 HydrophobicContact CG1-CD1 4.12Å; I139-A411 HydrophobicContact CG2-CB 4.01Å; I139-A412 HydrophobicContact CG2-CB 3.72Å
140	K	91.4	Very high	89.2	Confident	65 Å²	65	54.6 Å²	54.6	28%	0.283	29%	0.29	S	S	.	.	H	α-helix	trans	-76.8	-35.4	178	-67.1	-63.2	-168.9	-171.9	0	112.9	V136 A137 T138 A411 G416 W418	V136-K140 HydrophobicContact CG1-CG 4.41Å; V136-K140 WeakPolarHBondContact O-CG 3.49Å; V136-K140 PolarHBondContact O-N 3.04Å; A137-K140 PolarHBondContact O-N 3.38Å; T138-K140 VanDerWaalsContact C-N 3.25Å; T138-K140 PolarHBondContact O-N 3.12Å; K140-A411 PolarHBondContact NZ-O 3.05Å; K140-G416 VanDerWaalsContact NZ-C 3.27Å; K140-G416 VanDerWaalsContact NZ-CA 3.31Å; K140-G416 PolarHBondContact NZ-O 2.83Å; K140-W418 HydrophobicContact CD-CZ2 4.46Å; K140-W418 HydrophobicContact CG-CH2 3.98Å; K140-W418 HydrophobicContact CG-CZ2 4.23Å
141	S	92.5	Very high	87.7	Confident	42 Å²	42	57 Å²	57	29%	0.294	30%	0.299	S	S	.	.	H	α-helix	trans	-84.1	-39.6	-178.2	64.2	0	0	0	0	113	A137 T138 T227	A137-S141 WeakPolarHBondContact O-CB 3.46Å; A137-S141 PolarHBondContact O-N 3.27Å; A137-S141 PolarHBondContact O-OG 2.94Å; T138-S141 PolarHBondContact O-N 3.43Å; T138-S141 PolarHBondContact O-OG 2.9Å; S141-T227 WeakPolarHBondContact O-CG2 3.39Å
142	V	93.5	Very high	86.5	Confident	0 Å²	0	59 Å²	59	0%	0	31%	0.309	C	S	.	.			trans	-108.2	105	-171.3	-178.3	0	0	0	0	111.5	T138 F144 Y145 E223 V224	T138-V142 HydrophobicContact CG2-CB 4.35Å; T138-V142 HydrophobicContact CG2-CG2 4.31Å; T138-V142 WeakPolarHBondContact O-CB 3.2Å; T138-V142 PolarHBondContact O-N 3.25Å; V142-F144 HydrophobicContact CG1-CB 3.96Å; V142-F144 PolarHBondContact O-N 3.25Å; V142-Y145 HydrophobicContact CB-CD2 4Å; V142-Y145 HydrophobicContact CB-CE2 4.36Å; V142-Y145 HydrophobicContact CG1-CD2 3.74Å; V142-Y145 HydrophobicContact CG1-CE2 3.92Å; V142-Y145 PolarHBondContact O-N 3.37Å; V142-E223 HydrophobicContact CG1-CB 3.86Å; V142-V224 HydrophobicContact CG2-CG2 3.99Å
143	R	87.9	Confident	85.5	Confident	208 Å²	208	65.6 Å²	65.6	79%	0.785	34%	0.343	S	S	*	.	G	3₁₀ helix	trans	-64	-21.9	-178.3	-73.1	-170.2	160.1	-167.7	-5.5	115	Y145 T146 E147	R143-Y145 PolarHBondContact O-N 2.94Å; R143-T146 PolarHBondContact O-N 2.84Å; R143-T146 VanDerWaalsContact O-N 3.1Å; R143-T146 PolarHBondContact O-OG1 2.94Å; R143-E147 PolarHBondContact O-N 3.36Å
144	F	90.8	Very high	84.3	Confident	45 Å²	45	64.3 Å²	64.3	20%	0.197	33%	0.332	C	S	.	.	G	3₁₀ helix	trans	-55.4	-36.6	178.9	176.4	-97.9	0	0	0	112.8	V142 T146 E223 K278	V142-F144 HydrophobicContact CG1-CB 3.96Å; V142-F144 PolarHBondContact O-N 3.25Å; F144-T146 VanDerWaalsContact C-N 3.32Å; F144-T146 PolarHBondContact O-N 3.42Å; F144-E223 HydrophobicContact CB-CB 4.23Å; F144-E223 HydrophobicContact CB-CG 3.97Å; F144-E223 WeakPolarHBondContact CB-OE2 3.27Å; F144-E223 HydrophobicContact CD1-CG 3.72Å; F144-E223 HydrophobicContact CD2-CG 4.09Å; F144-E223 WeakPolarHBondContact CD2-OE2 3.45Å; F144-E223 HydrophobicContact CE1-CG 4.18Å; F144-E223 HydrophobicContact CG-CB 4.43Å; F144-E223 HydrophobicContact CG-CG 3.65Å; F144-K278 HydrophobicContact CD1-CD 3.94Å; F144-K278 HydrophobicContact CE1-CD 3.72Å; F144-K278 VanDerWaalsContact CE1-CE 3.44Å; F144-K278 HydrophobicContact CE1-CG 4.23Å; F144-K278 HydrophobicContact CZ-CD 4.25Å; F144-K278 VanDerWaalsContact CZ-CE 3.46Å; F144-K278 WeakPolarHBondContact O-CD 3.4Å; F144-K278 WeakPolarHBondContact O-CE 3.32Å; F144-K278 PolarHBondContact O-NZ 2.81Å
145	Y	89.8	Confident	83.6	Confident	16 Å²	16	63 Å²	63	6%	0.063	32%	0.324	C	S	.	.	G	3₁₀ helix	trans	-75.9	-18.1	-177.6	-68.7	-76.5	0	0	0	114	T138 I139 V142 R143 Y220 L274 K278	T138-Y145 HydrophobicContact CG2-CD2 3.89Å; T138-Y145 HydrophobicContact CG2-CE2 3.81Å; I139-Y145 HydrophobicContact CD1-CG 4.29Å; V142-Y145 HydrophobicContact CB-CD2 4Å; V142-Y145 HydrophobicContact CB-CE2 4.36Å; V142-Y145 HydrophobicContact CG1-CD2 3.74Å; V142-Y145 HydrophobicContact CG1-CE2 3.92Å; V142-Y145 PolarHBondContact O-N 3.37Å; R143-Y145 PolarHBondContact O-N 2.94Å; Y145-Y220 HydrophobicContact CE2-CD2 4.35Å; Y145-L274 HydrophobicContact CD1-CB 3.98Å; Y145-L274 HydrophobicContact CD1-CD2 4.22Å; Y145-L274 HydrophobicContact CD2-CD2 4.39Å; Y145-L274 HydrophobicContact CE1-CB 3.66Å; Y145-L274 HydrophobicContact CE1-CD2 4.45Å; Y145-L274 HydrophobicContact CE1-CG 4.45Å; Y145-L274 HydrophobicContact CG-CD2 4.2Å; Y145-K278 HydrophobicContact CD1-CB 4.07Å; Y145-K278 HydrophobicContact CD1-CD 4.43Å
146	T	87.7	Confident	83	Confident	60 Å²	60	65.8 Å²	65.8	37%	0.368	34%	0.342	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.5	-16.5	177.2	60.7	0	0	0	0	112.7	I139 R143 F144 A412	I139-T146 HydrophobicContact CG2-CG2 4Å; R143-T146 PolarHBondContact O-N 2.84Å; R143-T146 VanDerWaalsContact O-N 3.1Å; R143-T146 PolarHBondContact O-OG1 2.94Å; F144-T146 VanDerWaalsContact C-N 3.32Å; F144-T146 PolarHBondContact O-N 3.42Å; T146-A412 HydrophobicContact CG2-CB 3.98Å
147	E	85.6	Confident	82.4	Confident	116 Å²	116	69.1 Å²	69.1	54%	0.542	36%	0.356	S	S	.	.	S	Bend	trans	-73.8	133.2	-179.8	-164.3	175	-165.3	0	0	112.6	R143 N149 K278	R143-E147 PolarHBondContact O-N 3.36Å; E147-N149 PolarHBondContact O-N 3.04Å; E147-K278 PolarHBondContact O-NZ 3.33Å
148	K	76.1	Confident	81.8	Confident	143 Å²	143	69.8 Å²	69.8	62%	0.622	35%	0.354	S	S	*	.			trans	-89.7	98.1	-178.4	-62.4	-179.8	-176.7	178.4	0	110.5	G150 E282	K148-G150 PolarHBondContact O-N 2.59Å; K148-E282 WeakPolarHBondContact CE-OE1 3.29Å; K148-E282 IonicContact NZ-OE1 3.75Å; K148-E282 PolarHBondContact NZ-OE1 2.84Å; K148-E282 IonicContact NZ-OE2 3.37Å; K148-E282 PolarHBondContact NZ-OE2 3.48Å
149	N	61.3	Low	81	Confident	85 Å²	85	70.3 Å²	70.3	46%	0.455	36%	0.356	S	S	.	.			trans	-96.4	91.1	-178.8	-67.6	-10	0	0	0	111.5	E147 K278	E147-N149 PolarHBondContact O-N 3.04Å; N149-K278 PolarHBondContact ND2-NZ 2.96Å
150	G	60.2	Low	80.3	Confident	71 Å²	71	76.9 Å²	76.9	73%	0.732	39%	0.391	S	S	*	.	S	Bend	trans	58.5	-178.9	162.7	0	0	0	0	0	117	K148	K148-G150 PolarHBondContact O-N 2.59Å
151	Q	63.5	Low	79.9	Confident	135 Å²	135	75 Å²	75	63%	0.631	39%	0.386	S	S	*	.			trans	-78.8	123.7	-179.7	-168.9	170.4	-0.9	0	0	110.8	P156 T158	Q151-P156 PolarHBondContact NE2-O 3.47Å; Q151-T158 HydrophobicContact CG-CG2 4.48Å
152	L	72.1	Confident	79.3	Confident	40 Å²	40	79.7 Å²	79.7	21%	0.209	42%	0.415	C	S	.	.			trans	-91	145.8	-179.1	-62.9	153.5	0	0	0	110.2	Y154 T155 Y279	L152-Y154 HydrophobicContact CB-CD2 4.43Å; L152-Y154 HydrophobicContact CB-CE1 4.07Å; L152-Y154 HydrophobicContact CB-CE2 3.87Å; L152-Y154 HydrophobicContact CD1-CE2 4.13Å; L152-Y154 WeakPolarHBondContact CD1-OH 3.24Å; L152-Y154 WeakPolarHBondContact CD2-OH 3.26Å; L152-Y154 PolarHBondContact O-N 2.83Å; L152-Y154 VanDerWaalsContact O-N 3.13Å; L152-T155 CarbonylContact O-C 3.47Å; L152-T155 PolarHBondContact O-N 3.32Å; L152-T155 PolarHBondContact O-OG1 3.27Å; L152-Y279 HydrophobicContact CD1-CD1 4.37Å; L152-Y279 WeakPolarHBondContact CD1-O 3.42Å; L152-Y279 HydrophobicContact CD2-CD1 3.83Å; L152-Y279 HydrophobicContact CD2-CE1 4.31Å
153	I	73.2	Confident	79.2	Confident	139 Å²	139	82.1 Å²	82.1	71%	0.713	43%	0.432	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.4	-30.5	-172.3	-66.4	171.5	0	0	0	112.6	M1	M1-I153 HydrophobicContact SD-CD1 3.94Å
154	Y	72.1	Confident	79.2	Confident	74 Å²	74	77.2 Å²	77.2	29%	0.29	43%	0.425	S	S	.	.	T	Hydrogen-bonded Turn	trans	-92.6	-1.7	-178.9	46.2	-93.9	0	0	0	113.8	L152 P156 M178 Y279	L152-Y154 HydrophobicContact CB-CD2 4.43Å; L152-Y154 HydrophobicContact CB-CE1 4.07Å; L152-Y154 HydrophobicContact CB-CE2 3.87Å; L152-Y154 HydrophobicContact CD1-CE2 4.13Å; L152-Y154 WeakPolarHBondContact CD1-OH 3.24Å; L152-Y154 WeakPolarHBondContact CD2-OH 3.26Å; L152-Y154 PolarHBondContact O-N 2.83Å; L152-Y154 VanDerWaalsContact O-N 3.13Å; Y154-P156 WeakPolarHBondContact O-CD 3.46Å; Y154-M178 HydrophobicContact CD2-CE 4.05Å; Y154-M178 HydrophobicContact CD2-CG 4.42Å; Y154-M178 HydrophobicContact CD2-SD 3.49Å; Y154-M178 WeakPolarHBondContact CD2-SD 3.48Å; Y154-M178 HydrophobicContact CE2-CE 4.44Å; Y154-M178 HydrophobicContact CE2-SD 4.42Å; Y154-M178 HydrophobicContact CG-SD 3.82Å; Y154-Y279 WeakPolarHBondContact CE2-O 3.35Å; Y154-Y279 WeakPolarHBondContact OH-CB 3.38Å; Y154-Y279 WeakPolarHBondContact OH-CD1 3.38Å; Y154-Y279 VanDerWaalsContact OH-CG 3.28Å; Y154-Y279 PolarHBondContact OH-O 3.03Å
155	T	82	Confident	79.2	Confident	9 Å²	9	77.7 Å²	77.7	6%	0.055	44%	0.442	C	S	.	.			trans	-122	76	171.4	58	0	0	0	0	109.4	L152 F157 N174 P281	L152-T155 CarbonylContact O-C 3.47Å; L152-T155 PolarHBondContact O-N 3.32Å; L152-T155 PolarHBondContact O-OG1 3.27Å; T155-F157 PolarHBondContact O-N 2.98Å; T155-N174 HydrophobicContact CG2-CB 4.32Å; T155-P281 HydrophobicContact CG2-CG 3.97Å
156	P	83.6	Confident	79.1	Confident	57 Å²	57	81.7 Å²	81.7	37%	0.37	46%	0.461	S	S	.	.			trans	-67.8	-23.8	-176.5	27.5	-34.6	0	0	0	112.8	Q151 Y154 N174 I177	Q151-P156 PolarHBondContact NE2-O 3.47Å; Y154-P156 WeakPolarHBondContact O-CD 3.46Å; P156-N174 WeakPolarHBondContact CD-OD1 3.46Å; P156-I177 HydrophobicContact CG-CD1 3.68Å
157	F	84	Confident	79.2	Confident	85 Å²	85	82 Å²	82	37%	0.373	46%	0.456	S	S	.	.	S	Bend	trans	-96.1	125.9	179.5	-56	-74.4	0	0	0	110.6	T155 N170 L173 N174 I177	T155-F157 PolarHBondContact O-N 2.98Å; F157-N170 HydrophobicContact CB-CB 3.86Å; F157-L173 HydrophobicContact CD2-CB 3.7Å; F157-L173 HydrophobicContact CD2-CD1 4.2Å; F157-L173 HydrophobicContact CE1-CD1 4.45Å; F157-L173 HydrophobicContact CE2-CB 3.83Å; F157-L173 HydrophobicContact CE2-CD1 3.99Å; F157-L173 HydrophobicContact CZ-CD1 4.12Å; F157-N174 WeakPolarHBondContact CB-OD1 3.41Å; F157-N174 PolarHBondContact N-OD1 3.5Å; F157-N174 VanDerWaalsContact N-OD1 3.08Å; F157-N174 PolarHBondContact O-ND2 2.95Å; F157-I177 HydrophobicContact CD2-CD1 4.5Å; F157-I177 HydrophobicContact CE2-CD1 4.08Å
158	T	82.3	Confident	79.5	Confident	66 Å²	66	80.4 Å²	80.4	41%	0.405	45%	0.451	S	S	.	.			trans	-80.7	142	178.5	51.7	0	0	0	0	111.3	Q151 N170	Q151-T158 HydrophobicContact CG-CG2 4.48Å; T158-N170 PolarHBondContact O-ND2 2.93Å
159	E	78.1	Confident	80.2	Confident	15 Å²	15	78.3 Å²	78.3	7%	0.07	45%	0.446	C	S	.	.	S	Bend	trans	-87.9	-5.3	177.2	-66	-176.8	177.2	0	0	113.3	T161 R167 S171 P281 W283 S284	E159-T161 PolarHBondContact O-N 2.78Å; E159-R167 HydrophobicContact CB-CG 4.21Å; E159-R167 WeakPolarHBondContact O-CD 3.42Å; E159-R167 WeakPolarHBondContact O-CG 3.46Å; E159-R167 PolarHBondContact O-NE 2.98Å; E159-S171 WeakPolarHBondContact OE1-CB 3.44Å; E159-P281 VanDerWaalsContact CD-CB 3.43Å; E159-P281 HydrophobicContact CG-CB 4.3Å; E159-P281 WeakPolarHBondContact OE1-CB 3.34Å; E159-P281 WeakPolarHBondContact OE2-CB 3.45Å; E159-W283 WeakPolarHBondContact OE2-CB 3.5Å; E159-W283 PolarHBondContact OE2-N 2.97Å; E159-S284 VanDerWaalsContact OE1-CB 3.26Å; E159-S284 WeakPolarHBondContact OE1-CB 3.4Å; E159-S284 PolarHBondContact OE1-N 3.36Å; E159-S284 PolarHBondContact OE1-OG 3.36Å
160	D	78.5	Confident	81.6	Confident	143 Å²	143	75 Å²	75	77%	0.765	43%	0.428	S	S	*	.			trans	-79.9	54.1	-179.7	-55.7	-41.3	0	0	0	111.5
161	T	83.5	Confident	83.1	Confident	26 Å²	26	71.7 Å²	71.7	16%	0.16	39%	0.394	C	S	.	.			trans	-108.5	142.2	177.2	56.5	0	0	0	0	111.2	E159 S163 Q166 R167	E159-T161 PolarHBondContact O-N 2.78Å; T161-S163 VanDerWaalsContact C-N 3.26Å; T161-S163 PolarHBondContact O-N 3.44Å; T161-Q166 HydrophobicContact CG2-CG 4.27Å; T161-R167 WeakPolarHBondContact OG1-CA 3.45Å; T161-R167 PolarHBondContact OG1-N 3.04Å
162	P	80.4	Confident	84.5	Confident	140 Å²	140	67.9 Å²	67.9	91%	0.909	38%	0.379	S	S	*	.	S	Bend	trans	-69.6	-19.3	-175.2	27.7	-35.4	0	0	0	114
163	S	90.7	Very high	85.4	Confident	51 Å²	51	69 Å²	69	36%	0.357	39%	0.385	S	S	.	.	S	Bend	trans	-99.3	130.9	179.4	60.4	0	0	0	0	111.6	T161 G165 Q166 R167	T161-S163 VanDerWaalsContact C-N 3.26Å; T161-S163 PolarHBondContact O-N 3.44Å; S163-G165 VanDerWaalsContact C-N 3.31Å; S163-G165 PolarHBondContact O-N 3.03Å; S163-Q166 PolarHBondContact O-N 3.31Å; S163-Q166 WeakPolarHBondContact OG-CB 3.38Å; S163-Q166 PolarHBondContact OG-OE1 3.26Å; S163-R167 WeakPolarHBondContact O-CB 3.22Å; S163-R167 PolarHBondContact O-N 3.41Å
164	V	88.6	Confident	86.2	Confident	106 Å²	106	62.4 Å²	62.4	64%	0.642	35%	0.352	S	S	*	.	H	α-helix	trans	-61.6	-40	179.8	-179.7	0	0	0	0	111.4	Q166 R167 L168	V164-Q166 PolarHBondContact O-N 3.27Å; V164-R167 PolarHBondContact O-N 3.4Å; V164-L168 WeakPolarHBondContact O-CB 3.06Å; V164-L168 PolarHBondContact O-N 3.4Å
165	G	89.1	Confident	87.1	Confident	54 Å²	54	59 Å²	59	56%	0.557	34%	0.339	S	S	*	.	H	α-helix	trans	-63.7	-40.5	178.9	0	0	0	0	0	113.1	S163 L168 L169	S163-G165 VanDerWaalsContact C-N 3.31Å; S163-G165 PolarHBondContact O-N 3.03Å; G165-L168 PolarHBondContact O-N 3.49Å; G165-L169 WeakPolarHBondContact O-CB 3.38Å; G165-L169 PolarHBondContact O-N 3.1Å
166	Q	88.6	Confident	87.5	Confident	100 Å²	100	63.6 Å²	63.6	47%	0.467	36%	0.362	S	S	.	.	H	α-helix	trans	-72.4	-36.6	176.9	-165.6	173.6	-1.7	0	0	111.3	T161 S163 V164 L168 L169 N170	T161-Q166 HydrophobicContact CG2-CG 4.27Å; S163-Q166 PolarHBondContact O-N 3.31Å; S163-Q166 WeakPolarHBondContact OG-CB 3.38Å; S163-Q166 PolarHBondContact OG-OE1 3.26Å; V164-Q166 PolarHBondContact O-N 3.27Å; Q166-L168 VanDerWaalsContact C-N 3.35Å; Q166-L169 PolarHBondContact O-N 3.01Å; Q166-N170 VanDerWaalsContact O-CB 3.29Å; Q166-N170 WeakPolarHBondContact O-CB 3.4Å; Q166-N170 PolarHBondContact O-N 2.94Å; Q166-N170 PolarHBondContact O-OD1 3.29Å
167	R	89.9	Confident	87.9	Confident	67 Å²	67	63.8 Å²	63.8	25%	0.253	36%	0.359	S	S	.	.	H	α-helix	trans	-59.8	-46.4	172.7	-174.4	170.7	-170.3	-168.9	-0.5	111.3	E159 T161 S163 V164 N170 S171 E282 W283	E159-R167 HydrophobicContact CB-CG 4.21Å; E159-R167 WeakPolarHBondContact O-CD 3.42Å; E159-R167 WeakPolarHBondContact O-CG 3.46Å; E159-R167 PolarHBondContact O-NE 2.98Å; T161-R167 WeakPolarHBondContact OG1-CA 3.45Å; T161-R167 PolarHBondContact OG1-N 3.04Å; S163-R167 WeakPolarHBondContact O-CB 3.22Å; S163-R167 PolarHBondContact O-N 3.41Å; V164-R167 PolarHBondContact O-N 3.4Å; R167-N170 PolarHBondContact O-N 3.23Å; R167-S171 WeakPolarHBondContact O-CB 3.48Å; R167-S171 PolarHBondContact O-N 3.25Å; R167-S171 PolarHBondContact O-OG 3.49Å; R167-E282 IonicContact NH2-OE2 2.7Å; R167-W283 HydrophobicContact CG-CG 4.32Å; R167-W283 VanDerWaalsContact NE-NE1 3.12Å
168	L	90.9	Very high	88.1	Confident	82 Å²	82	61 Å²	61	43%	0.429	35%	0.348	S	S	.	.	H	α-helix	trans	-61.9	-50.1	176.2	-176	66.4	0	0	0	110.9	V164 G165 Q166 N170 S171 V172 W283	V164-L168 WeakPolarHBondContact O-CB 3.06Å; V164-L168 PolarHBondContact O-N 3.4Å; G165-L168 PolarHBondContact O-N 3.49Å; Q166-L168 VanDerWaalsContact C-N 3.35Å; L168-N170 VanDerWaalsContact C-N 3.35Å; L168-N170 PolarHBondContact O-N 3.39Å; L168-S171 WeakPolarHBondContact CA-OG 3.27Å; L168-S171 PolarHBondContact O-N 2.95Å; L168-S171 PolarHBondContact O-OG 3Å; L168-V172 HydrophobicContact CD1-CG2 4.43Å; L168-V172 HydrophobicContact CG-CG2 4.45Å; L168-V172 VanDerWaalsContact O-CG2 3.32Å; L168-V172 WeakPolarHBondContact O-CG2 3.31Å; L168-V172 PolarHBondContact O-N 2.89Å; L168-W283 HydrophobicContact CD1-CE3 4.3Å; L168-W283 HydrophobicContact CD1-CZ3 4.41Å
169	L	91.7	Very high	88.5	Confident	100 Å²	100	59.2 Å²	59.2	52%	0.524	34%	0.335	S	S	.	.	H	α-helix	trans	-59.4	-44.8	179.9	-175.2	147.1	0	0	0	111.8	G165 Q166 S171 V172 L173	G165-L169 WeakPolarHBondContact O-CB 3.38Å; G165-L169 PolarHBondContact O-N 3.1Å; Q166-L169 PolarHBondContact O-N 3.01Å; L169-S171 PolarHBondContact O-N 3.35Å; L169-V172 PolarHBondContact O-N 3.19Å; L169-L173 HydrophobicContact CD2-CD1 3.56Å; L169-L173 HydrophobicContact CD2-CG 4.21Å; L169-L173 WeakPolarHBondContact O-CG 3.29Å; L169-L173 PolarHBondContact O-N 3.48Å
170	N	90.6	Very high	89.1	Confident	16 Å²	16	61.3 Å²	61.3	9%	0.086	35%	0.352	C	S	.	.	H	α-helix	trans	-62	-42.9	176.4	-71.4	-3.3	0	0	0	111.6	F157 T158 Q166 R167 L168 L173 N174	F157-N170 HydrophobicContact CB-CB 3.86Å; T158-N170 PolarHBondContact O-ND2 2.93Å; Q166-N170 VanDerWaalsContact O-CB 3.29Å; Q166-N170 WeakPolarHBondContact O-CB 3.4Å; Q166-N170 PolarHBondContact O-N 2.94Å; Q166-N170 PolarHBondContact O-OD1 3.29Å; R167-N170 PolarHBondContact O-N 3.23Å; L168-N170 VanDerWaalsContact C-N 3.35Å; L168-N170 PolarHBondContact O-N 3.39Å; N170-L173 PolarHBondContact O-N 2.9Å; N170-N174 PolarHBondContact O-N 2.65Å; N170-N174 PolarHBondContact O-ND2 3.34Å
171	S	91	Very high	89.7	Confident	0 Å²	0	58.1 Å²	58.1	0%	0	34%	0.338	C	S	.	.	H	α-helix	trans	-64.4	-40.8	177.4	72.9	0	0	0	0	112	E159 R167 L168 L169 N174 T175	E159-S171 WeakPolarHBondContact OE1-CB 3.44Å; R167-S171 WeakPolarHBondContact O-CB 3.48Å; R167-S171 PolarHBondContact O-N 3.25Å; R167-S171 PolarHBondContact O-OG 3.49Å; L168-S171 WeakPolarHBondContact CA-OG 3.27Å; L168-S171 PolarHBondContact O-N 2.95Å; L168-S171 PolarHBondContact O-OG 3Å; L169-S171 PolarHBondContact O-N 3.35Å; S171-N174 PolarHBondContact O-N 3.25Å; S171-T175 WeakPolarHBondContact O-CB 3.46Å; S171-T175 PolarHBondContact O-N 3.26Å; S171-T175 PolarHBondContact O-OG1 2.99Å
172	V	93	Very high	89.9	Confident	55 Å²	55	59.8 Å²	59.8	33%	0.333	35%	0.345	S	S	.	.	H	α-helix	trans	-64.3	-43.8	175.9	170.5	0	0	0	0	110.6	L168 L169 T175 L176 V287	L168-V172 HydrophobicContact CD1-CG2 4.43Å; L168-V172 HydrophobicContact CG-CG2 4.45Å; L168-V172 VanDerWaalsContact O-CG2 3.32Å; L168-V172 WeakPolarHBondContact O-CG2 3.31Å; L168-V172 PolarHBondContact O-N 2.89Å; L169-V172 PolarHBondContact O-N 3.19Å; V172-T175 PolarHBondContact O-N 2.84Å; V172-L176 HydrophobicContact CG1-CD1 4.15Å; V172-L176 HydrophobicContact CG1-CG 4.41Å; V172-L176 WeakPolarHBondContact O-CB 3.31Å; V172-L176 WeakPolarHBondContact O-CG 3.48Å; V172-L176 PolarHBondContact O-N 3.28Å; V172-V287 HydrophobicContact CG2-CG1 4.13Å
173	L	91.3	Very high	90.3	Very high	64 Å²	64	54.8 Å²	54.8	34%	0.335	31%	0.311	S	S	.	.	H	α-helix	trans	-62.4	-44	177.1	-72	176.4	0	0	0	112	F157 L169 N170 L176 I177	F157-L173 HydrophobicContact CD2-CB 3.7Å; F157-L173 HydrophobicContact CD2-CD1 4.2Å; F157-L173 HydrophobicContact CE1-CD1 4.45Å; F157-L173 HydrophobicContact CE2-CB 3.83Å; F157-L173 HydrophobicContact CE2-CD1 3.99Å; F157-L173 HydrophobicContact CZ-CD1 4.12Å; L169-L173 HydrophobicContact CD2-CD1 3.56Å; L169-L173 HydrophobicContact CD2-CG 4.21Å; L169-L173 WeakPolarHBondContact O-CG 3.29Å; L169-L173 PolarHBondContact O-N 3.48Å; N170-L173 PolarHBondContact O-N 2.9Å; L173-L176 PolarHBondContact O-N 2.84Å; L173-I177 WeakPolarHBondContact O-CG1 3.2Å; L173-I177 PolarHBondContact O-N 2.94Å; L173-I177 VanDerWaalsContact O-N 3.09Å
174	N	90.3	Very high	90.3	Very high	1 Å²	1	56.4 Å²	56.4	1%	0.005	32%	0.319	C	S	.	.	H	α-helix	trans	-60.2	-46.1	174.2	-73.7	-25	0	0	0	111.7	T155 P156 F157 N170 S171 L176 I177 M178	T155-N174 HydrophobicContact CG2-CB 4.32Å; P156-N174 WeakPolarHBondContact CD-OD1 3.46Å; F157-N174 WeakPolarHBondContact CB-OD1 3.41Å; F157-N174 PolarHBondContact N-OD1 3.5Å; F157-N174 VanDerWaalsContact N-OD1 3.08Å; F157-N174 PolarHBondContact O-ND2 2.95Å; N170-N174 PolarHBondContact O-N 2.65Å; N170-N174 PolarHBondContact O-ND2 3.34Å; S171-N174 PolarHBondContact O-N 3.25Å; N174-L176 VanDerWaalsContact C-N 3.34Å; N174-L176 PolarHBondContact O-N 3.28Å; N174-I177 PolarHBondContact O-N 2.99Å; N174-M178 PolarHBondContact O-N 3.22Å
175	T	90.4	Very high	90.3	Very high	3 Å²	3	56 Å²	56	2%	0.018	31%	0.311	C	S	.	.	H	α-helix	trans	-60.7	-42.5	177.4	-66.1	0	0	0	0	111.6	S171 V172 I177 M178 I179 S284 V287 I288 A291	S171-T175 WeakPolarHBondContact O-CB 3.46Å; S171-T175 PolarHBondContact O-N 3.26Å; S171-T175 PolarHBondContact O-OG1 2.99Å; V172-T175 PolarHBondContact O-N 2.84Å; T175-I177 PolarHBondContact O-N 3.47Å; T175-M178 PolarHBondContact O-N 2.94Å; T175-I179 HydrophobicContact CG2-CD1 3.59Å; T175-I179 HydrophobicContact CG2-CG1 4.23Å; T175-I179 WeakPolarHBondContact O-CB 3.24Å; T175-I179 WeakPolarHBondContact O-CG1 3Å; T175-I179 PolarHBondContact O-N 3.34Å; T175-S284 PolarHBondContact OG1-O 3.36Å; T175-S284 VanDerWaalsContact OG1-O 3.12Å; T175-V287 HydrophobicContact CG2-CB 4.37Å; T175-V287 HydrophobicContact CG2-CG1 3.8Å; T175-I288 HydrophobicContact CG2-CB 4.27Å; T175-I288 HydrophobicContact CG2-CG1 3.5Å; T175-I288 VanDerWaalsContact CG2-CG1 3.5Å; T175-A291 HydrophobicContact CG2-CB 4.18Å
176	L	91.6	Very high	90.2	Very high	104 Å²	104	55.4 Å²	55.4	55%	0.545	30%	0.297	S	S	.	.	H	α-helix	trans	-61.4	-42.6	176.6	-76.2	173.9	0	0	0	112	V172 L173 N174 S180	V172-L176 HydrophobicContact CG1-CD1 4.15Å; V172-L176 HydrophobicContact CG1-CG 4.41Å; V172-L176 WeakPolarHBondContact O-CB 3.31Å; V172-L176 WeakPolarHBondContact O-CG 3.48Å; V172-L176 PolarHBondContact O-N 3.28Å; L173-L176 PolarHBondContact O-N 2.84Å; N174-L176 VanDerWaalsContact C-N 3.34Å; N174-L176 PolarHBondContact O-N 3.28Å; L176-S180 VanDerWaalsContact O-CB 3.28Å; L176-S180 WeakPolarHBondContact O-CB 3.3Å; L176-S180 PolarHBondContact O-N 3.47Å; L176-S180 PolarHBondContact O-OG 3.02Å
177	I	91.2	Very high	90.1	Very high	61 Å²	61	54.6 Å²	54.6	31%	0.313	30%	0.295	S	S	.	.	H	α-helix	trans	-61.7	-49.2	175.6	-66	164.8	0	0	0	110.1	P156 F157 L173 N174 T175 S180 V181	P156-I177 HydrophobicContact CG-CD1 3.68Å; F157-I177 HydrophobicContact CD2-CD1 4.5Å; F157-I177 HydrophobicContact CE2-CD1 4.08Å; L173-I177 WeakPolarHBondContact O-CG1 3.2Å; L173-I177 PolarHBondContact O-N 2.94Å; L173-I177 VanDerWaalsContact O-N 3.09Å; N174-I177 PolarHBondContact O-N 2.99Å; T175-I177 PolarHBondContact O-N 3.47Å; I177-S180 PolarHBondContact O-N 3.28Å; I177-S180 PolarHBondContact O-OG 3.3Å; I177-V181 PolarHBondContact O-N 2.85Å; I177-V181 VanDerWaalsContact O-N 3.14Å
178	M	88.7	Confident	90.1	Very high	28 Å²	28	55.6 Å²	55.6	14%	0.138	30%	0.301	C	S	.	.	H	α-helix	trans	-61.4	-46.6	179.5	-79.1	-71.6	-78.9	0	0	112.8	Y154 N174 T175 S180 V181 I182 L280 I288	Y154-M178 HydrophobicContact CD2-CE 4.05Å; Y154-M178 HydrophobicContact CD2-CG 4.42Å; Y154-M178 HydrophobicContact CD2-SD 3.49Å; Y154-M178 WeakPolarHBondContact CD2-SD 3.48Å; Y154-M178 HydrophobicContact CE2-CE 4.44Å; Y154-M178 HydrophobicContact CE2-SD 4.42Å; Y154-M178 HydrophobicContact CG-SD 3.82Å; N174-M178 PolarHBondContact O-N 3.22Å; T175-M178 PolarHBondContact O-N 2.94Å; M178-S180 VanDerWaalsContact C-N 3.32Å; M178-S180 PolarHBondContact O-N 3.26Å; M178-V181 PolarHBondContact O-N 3.48Å; M178-I182 WeakPolarHBondContact O-CG1 3.46Å; M178-I182 PolarHBondContact O-N 3.36Å; M178-I182 VanDerWaalsContact O-N 3.1Å; M178-L280 HydrophobicContact CE-CD2 3.85Å; M178-I288 HydrophobicContact CB-CD1 3.76Å; M178-I288 HydrophobicContact CE-CD1 4.46Å; M178-I288 HydrophobicContact CG-CD1 4.2Å
179	I	90.2	Very high	89.8	Confident	27 Å²	27	54 Å²	54	14%	0.138	29%	0.293	C	S	.	.	H	α-helix	trans	-63.2	-40.4	176.9	-73.1	175.4	0	0	0	110.7	T175 V181 I182 V183 A291 I292	T175-I179 HydrophobicContact CG2-CD1 3.59Å; T175-I179 HydrophobicContact CG2-CG1 4.23Å; T175-I179 WeakPolarHBondContact O-CB 3.24Å; T175-I179 WeakPolarHBondContact O-CG1 3Å; T175-I179 PolarHBondContact O-N 3.34Å; I179-V181 VanDerWaalsContact C-N 3.26Å; I179-V181 PolarHBondContact O-N 3.17Å; I179-I182 PolarHBondContact O-N 3.04Å; I179-I182 VanDerWaalsContact O-N 3.14Å; I179-V183 HydrophobicContact CG2-CG2 4.04Å; I179-V183 VanDerWaalsContact O-CG2 3.29Å; I179-V183 WeakPolarHBondContact O-CG2 3.37Å; I179-V183 PolarHBondContact O-N 3.27Å; I179-A291 HydrophobicContact CD1-CB 3.25Å; I179-I292 HydrophobicContact CD1-CG1 4.46Å; I179-I292 HydrophobicContact CG1-CG1 4.43Å
180	S	90.3	Very high	89.4	Confident	60 Å²	60	49.7 Å²	49.7	42%	0.42	27%	0.271	S	S	.	.	H	α-helix	trans	-58.4	-39.6	176.7	77.9	0	0	0	0	112	L176 I177 M178 V183 V184	L176-S180 VanDerWaalsContact O-CB 3.28Å; L176-S180 WeakPolarHBondContact O-CB 3.3Å; L176-S180 PolarHBondContact O-N 3.47Å; L176-S180 PolarHBondContact O-OG 3.02Å; I177-S180 PolarHBondContact O-N 3.28Å; I177-S180 PolarHBondContact O-OG 3.3Å; M178-S180 VanDerWaalsContact C-N 3.32Å; M178-S180 PolarHBondContact O-N 3.26Å; S180-V183 PolarHBondContact O-N 2.91Å; S180-V184 WeakPolarHBondContact O-CB 3.43Å; S180-V184 VanDerWaalsContact O-CG2 3.23Å; S180-V184 WeakPolarHBondContact O-CG2 3.33Å; S180-V184 PolarHBondContact O-N 3.24Å
181	V	90.6	Very high	89.2	Confident	76 Å²	76	51.8 Å²	51.8	46%	0.461	28%	0.284	S	S	.	.	H	α-helix	trans	-65.9	-44.6	175.9	174.5	0	0	0	0	110.8	I177 M178 I179 V183 V184 M185	I177-V181 PolarHBondContact O-N 2.85Å; I177-V181 VanDerWaalsContact O-N 3.14Å; M178-V181 PolarHBondContact O-N 3.48Å; I179-V181 VanDerWaalsContact C-N 3.26Å; I179-V181 PolarHBondContact O-N 3.17Å; V181-V183 PolarHBondContact O-N 3.12Å; V181-V184 PolarHBondContact O-N 2.78Å; V181-M185 HydrophobicContact CG1-CG 4.35Å; V181-M185 WeakPolarHBondContact O-CB 3.33Å; V181-M185 VanDerWaalsContact O-CG 3.23Å; V181-M185 WeakPolarHBondContact O-CG 3.19Å; V181-M185 PolarHBondContact O-N 3.49Å
182	I	88.7	Confident	89	Confident	60 Å²	60	53 Å²	53	31%	0.308	29%	0.291	S	S	.	.	H	α-helix	trans	-58.9	-48.3	176.6	-65.1	169.7	0	0	0	110	M178 I179 V184 M185 T186 I292	M178-I182 WeakPolarHBondContact O-CG1 3.46Å; M178-I182 PolarHBondContact O-N 3.36Å; M178-I182 VanDerWaalsContact O-N 3.1Å; I179-I182 PolarHBondContact O-N 3.04Å; I179-I182 VanDerWaalsContact O-N 3.14Å; I182-V184 PolarHBondContact O-N 3.37Å; I182-M185 PolarHBondContact O-N 3.26Å; I182-T186 HydrophobicContact CG2-CG2 4.4Å; I182-T186 WeakPolarHBondContact O-CG2 3.23Å; I182-T186 PolarHBondContact O-N 3.19Å; I182-T186 PolarHBondContact O-OG1 2.85Å; I182-I292 HydrophobicContact CD1-CD1 4.2Å
183	V	88.8	Confident	88.4	Confident	35 Å²	35	51 Å²	51	21%	0.212	28%	0.277	C	S	.	.	H	α-helix	trans	-63	-42.3	179.5	173.6	0	0	0	0	112	I179 S180 V181 M185 T186 I187 Y295	I179-V183 HydrophobicContact CG2-CG2 4.04Å; I179-V183 VanDerWaalsContact O-CG2 3.29Å; I179-V183 WeakPolarHBondContact O-CG2 3.37Å; I179-V183 PolarHBondContact O-N 3.27Å; S180-V183 PolarHBondContact O-N 2.91Å; V181-V183 PolarHBondContact O-N 3.12Å; V183-M185 VanDerWaalsContact C-N 3.34Å; V183-T186 WeakPolarHBondContact CA-OG1 3.31Å; V183-T186 PolarHBondContact O-N 2.94Å; V183-T186 PolarHBondContact O-OG1 3.36Å; V183-I187 HydrophobicContact CG1-CD1 3.78Å; V183-I187 HydrophobicContact CG1-CG1 4.45Å; V183-I187 WeakPolarHBondContact O-CB 3.44Å; V183-I187 VanDerWaalsContact O-CG1 3.24Å; V183-I187 WeakPolarHBondContact O-CG1 3.45Å; V183-I187 PolarHBondContact O-N 2.88Å; V183-Y295 HydrophobicContact CG2-CD2 4.21Å; V183-Y295 HydrophobicContact CG2-CE2 3.6Å
184	V	91.2	Very high	88.1	Confident	86 Å²	86	54.9 Å²	54.9	52%	0.521	29%	0.291	S	S	.	.	H	α-helix	trans	-64.5	-41.7	176.8	169	0	0	0	0	110.8	S180 V181 I182 I187 F188	S180-V184 WeakPolarHBondContact O-CB 3.43Å; S180-V184 VanDerWaalsContact O-CG2 3.23Å; S180-V184 WeakPolarHBondContact O-CG2 3.33Å; S180-V184 PolarHBondContact O-N 3.24Å; V181-V184 PolarHBondContact O-N 2.78Å; I182-V184 PolarHBondContact O-N 3.37Å; V184-I187 PolarHBondContact O-N 3.3Å; V184-F188 VanDerWaalsContact O-CB 3.31Å; V184-F188 WeakPolarHBondContact O-CB 2.97Å; V184-F188 PolarHBondContact O-N 3.07Å
185	M	87.8	Confident	87.9	Confident	97 Å²	97	63.1 Å²	63.1	48%	0.478	32%	0.324	S	S	.	.	H	α-helix	trans	-66.8	-38.2	177.1	-68.3	-64.4	137.3	0	0	112.3	V181 I182 V183 F188 L189	V181-M185 HydrophobicContact CG1-CG 4.35Å; V181-M185 WeakPolarHBondContact O-CB 3.33Å; V181-M185 VanDerWaalsContact O-CG 3.23Å; V181-M185 WeakPolarHBondContact O-CG 3.19Å; V181-M185 PolarHBondContact O-N 3.49Å; I182-M185 PolarHBondContact O-N 3.26Å; V183-M185 VanDerWaalsContact C-N 3.34Å; M185-F188 PolarHBondContact O-N 3.26Å; M185-L189 PolarHBondContact O-N 3.37Å
186	T	88.1	Confident	87.5	Confident	41 Å²	41	70.6 Å²	70.6	25%	0.252	35%	0.351	S	S	.	.	H	α-helix	trans	-66.6	-44.5	175.6	57.4	0	0	0	0	111.2	I182 V183 F188 L189 V190	I182-T186 HydrophobicContact CG2-CG2 4.4Å; I182-T186 WeakPolarHBondContact O-CG2 3.23Å; I182-T186 PolarHBondContact O-N 3.19Å; I182-T186 PolarHBondContact O-OG1 2.85Å; V183-T186 WeakPolarHBondContact CA-OG1 3.31Å; V183-T186 PolarHBondContact O-N 2.94Å; V183-T186 PolarHBondContact O-OG1 3.36Å; T186-F188 VanDerWaalsContact C-N 3.32Å; T186-F188 PolarHBondContact O-N 3.48Å; T186-L189 PolarHBondContact O-N 2.88Å; T186-V190 WeakPolarHBondContact O-CG2 3.36Å; T186-V190 PolarHBondContact O-N 3.01Å
187	I	86.8	Confident	87.1	Confident	83 Å²	83	68 Å²	68	43%	0.426	34%	0.342	S	S	.	.	H	α-helix	trans	-60.3	-43.9	174.5	-67.1	166.7	0	0	0	110.5	V183 V184 L189 V190 V191	V183-I187 HydrophobicContact CG1-CD1 3.78Å; V183-I187 HydrophobicContact CG1-CG1 4.45Å; V183-I187 WeakPolarHBondContact O-CB 3.44Å; V183-I187 VanDerWaalsContact O-CG1 3.24Å; V183-I187 WeakPolarHBondContact O-CG1 3.45Å; V183-I187 PolarHBondContact O-N 2.88Å; V184-I187 PolarHBondContact O-N 3.3Å; I187-L189 VanDerWaalsContact C-N 3.33Å; I187-L189 PolarHBondContact O-N 3.44Å; I187-V190 PolarHBondContact O-N 3.21Å; I187-V191 HydrophobicContact CG2-CG2 4.08Å; I187-V191 WeakPolarHBondContact O-CB 3.33Å; I187-V191 WeakPolarHBondContact O-CG2 3.28Å; I187-V191 PolarHBondContact O-N 3.14Å
188	F	89.3	Confident	86.6	Confident	88 Å²	88	68.5 Å²	68.5	39%	0.386	34%	0.34	S	S	.	.	H	α-helix	trans	-58.7	-43.7	177.4	178.8	-108.2	0	0	0	112.2	V184 M185 T186 V191 L192 F200 W204	V184-F188 VanDerWaalsContact O-CB 3.31Å; V184-F188 WeakPolarHBondContact O-CB 2.97Å; V184-F188 PolarHBondContact O-N 3.07Å; M185-F188 PolarHBondContact O-N 3.26Å; T186-F188 VanDerWaalsContact C-N 3.32Å; T186-F188 PolarHBondContact O-N 3.48Å; F188-V191 PolarHBondContact O-N 3.1Å; F188-L192 HydrophobicContact CD1-CD1 3.78Å; F188-L192 HydrophobicContact CE1-CD1 3.34Å; F188-L192 HydrophobicContact CE1-CG 4.36Å; F188-L192 HydrophobicContact CE2-CD1 4.18Å; F188-L192 HydrophobicContact CE2-CG 4.38Å; F188-L192 HydrophobicContact CG-CD1 4.37Å; F188-L192 HydrophobicContact CZ-CD1 3.57Å; F188-L192 HydrophobicContact CZ-CG 4.21Å; F188-L192 WeakPolarHBondContact O-CG 3.23Å; F188-L192 PolarHBondContact O-N 3.48Å; F188-F200 HydrophobicContact CE1-CE1 4.15Å; F188-F200 HydrophobicContact CZ-CE1 4.23Å; F188-W204 HydrophobicContact CE1-CH2 4.35Å; F188-W204 HydrophobicContact CE1-CZ3 4.08Å
189	L	84.6	Confident	86.6	Confident	48 Å²	48	76.5 Å²	76.5	25%	0.251	37%	0.374	S	S	.	.	H	α-helix	trans	-62.6	-46.8	174.7	-169.4	160.8	0	0	0	111.5	M185 T186 I187 V191 L192 Y193 L310	M185-L189 PolarHBondContact O-N 3.37Å; T186-L189 PolarHBondContact O-N 2.88Å; I187-L189 VanDerWaalsContact C-N 3.33Å; I187-L189 PolarHBondContact O-N 3.44Å; L189-V191 VanDerWaalsContact C-N 3.29Å; L189-V191 PolarHBondContact O-N 3.39Å; L189-L192 PolarHBondContact O-N 3.39Å; L189-Y193 WeakPolarHBondContact O-CB 3.44Å; L189-Y193 PolarHBondContact O-N 3.41Å; L189-L310 HydrophobicContact CD2-CD1 4.21Å; L189-L310 HydrophobicContact CD2-CD2 4.39Å
190	V	83.7	Confident	86.5	Confident	11 Å²	11	79.8 Å²	79.8	7%	0.067	39%	0.387	C	S	.	.	H	α-helix	trans	-59.1	-42.5	177.6	177.5	0	0	0	0	111.1	T186 I187 Y193 K194 P306 M309 L310	T186-V190 WeakPolarHBondContact O-CG2 3.36Å; T186-V190 PolarHBondContact O-N 3.01Å; I187-V190 PolarHBondContact O-N 3.21Å; V190-Y193 WeakPolarHBondContact O-CB 3.35Å; V190-Y193 PolarHBondContact O-N 3.47Å; V190-K194 WeakPolarHBondContact O-CB 3.4Å; V190-K194 PolarHBondContact O-N 2.96Å; V190-P306 HydrophobicContact CG2-CB 3.83Å; V190-M309 HydrophobicContact CG1-CE 3.56Å; V190-M309 HydrophobicContact CG1-SD 4.24Å; V190-L310 HydrophobicContact CB-CG 4.45Å; V190-L310 HydrophobicContact CG1-CG 4.45Å; V190-L310 HydrophobicContact CG2-CD1 3.51Å; V190-L310 HydrophobicContact CG2-CD2 4.31Å; V190-L310 HydrophobicContact CG2-CG 3.75Å
191	V	86.5	Confident	86.3	Confident	59 Å²	59	77.2 Å²	77.2	36%	0.358	37%	0.369	S	S	.	.	H	α-helix	trans	-65.3	-46.3	179.1	169	0	0	0	0	110.8	I187 F188 L189 Y193 K194 Y195	I187-V191 HydrophobicContact CG2-CG2 4.08Å; I187-V191 WeakPolarHBondContact O-CB 3.33Å; I187-V191 WeakPolarHBondContact O-CG2 3.28Å; I187-V191 PolarHBondContact O-N 3.14Å; F188-V191 PolarHBondContact O-N 3.1Å; L189-V191 VanDerWaalsContact C-N 3.29Å; L189-V191 PolarHBondContact O-N 3.39Å; V191-Y193 VanDerWaalsContact C-N 3.27Å; V191-Y193 PolarHBondContact O-N 2.87Å; V191-K194 PolarHBondContact O-N 3.24Å; V191-Y195 HydrophobicContact CG1-CD2 3.5Å; V191-Y195 HydrophobicContact CG1-CE2 3.34Å; V191-Y195 WeakPolarHBondContact O-CD2 3.08Å; V191-Y195 PolarHBondContact O-N 2.92Å
192	L	86	Confident	85.9	Confident	27 Å²	27	78.5 Å²	78.5	14%	0.141	37%	0.369	C	S	.	.	H	α-helix	trans	-59.9	-39	174.5	-76.1	167.8	0	0	0	112.5	F188 L189 Y195 R196 C197 F200 I201	F188-L192 HydrophobicContact CD1-CD1 3.78Å; F188-L192 HydrophobicContact CE1-CD1 3.34Å; F188-L192 HydrophobicContact CE1-CG 4.36Å; F188-L192 HydrophobicContact CE2-CD1 4.18Å; F188-L192 HydrophobicContact CE2-CG 4.38Å; F188-L192 HydrophobicContact CG-CD1 4.37Å; F188-L192 HydrophobicContact CZ-CD1 3.57Å; F188-L192 HydrophobicContact CZ-CG 4.21Å; F188-L192 WeakPolarHBondContact O-CG 3.23Å; F188-L192 PolarHBondContact O-N 3.48Å; L189-L192 PolarHBondContact O-N 3.39Å; L192-Y195 PolarHBondContact O-N 3.08Å; L192-R196 PolarHBondContact O-N 3.22Å; L192-C197 HydrophobicContact CD2-CB 3.98Å; L192-C197 PolarHBondContact O-N 3.38Å; L192-C197 VanDerWaalsContact O-N 3.1Å; L192-F200 HydrophobicContact CD1-CD1 3.53Å; L192-F200 HydrophobicContact CD1-CE1 3.5Å; L192-F200 VanDerWaalsContact CD1-CE1 3.5Å; L192-F200 HydrophobicContact CD2-CD1 3.92Å; L192-F200 HydrophobicContact CD2-CE1 4.33Å; L192-F200 HydrophobicContact CG-CD1 4.34Å; L192-I201 HydrophobicContact CB-CD1 4.19Å; L192-I201 HydrophobicContact CB-CG1 4.03Å
193	Y	81.5	Confident	85.9	Confident	12 Å²	12	77.2 Å²	77.2	5%	0.047	37%	0.371	C	S	.	.	H	α-helix	trans	-63.8	-44.5	175.8	-173.2	-100.3	0	0	0	111	L189 V190 V191 Y195 R196 Y198 I201 L310 T313 F322	L189-Y193 WeakPolarHBondContact O-CB 3.44Å; L189-Y193 PolarHBondContact O-N 3.41Å; V190-Y193 WeakPolarHBondContact O-CB 3.35Å; V190-Y193 PolarHBondContact O-N 3.47Å; V191-Y193 VanDerWaalsContact C-N 3.27Å; V191-Y193 PolarHBondContact O-N 2.87Å; Y193-Y195 VanDerWaalsContact C-N 3.34Å; Y193-Y195 PolarHBondContact O-N 2.89Å; Y193-R196 PolarHBondContact O-N 3.01Å; Y193-R196 VanDerWaalsContact O-N 3.1Å; Y193-Y198 HydrophobicContact CE2-CE1 4.17Å; Y193-I201 HydrophobicContact CD2-CD1 4.13Å; Y193-L310 HydrophobicContact CD1-CD2 3.6Å; Y193-L310 HydrophobicContact CD2-CD2 4.49Å; Y193-L310 HydrophobicContact CE1-CD2 4.2Å; Y193-L310 HydrophobicContact CG-CD2 3.76Å; Y193-T313 HydrophobicContact CD1-CG2 4.43Å; Y193-T313 HydrophobicContact CE1-CG2 3.7Å; Y193-F322 HydrophobicContact CD2-CE2 4.17Å; Y193-F322 HydrophobicContact CD2-CZ 4.1Å; Y193-F322 HydrophobicContact CE2-CE2 4.23Å; Y193-F322 HydrophobicContact CE2-CZ 4.19Å
194	K	83.3	Confident	85.9	Confident	146 Å²	146	81.3 Å²	81.3	64%	0.635	38%	0.383	S	S	*	.	H	α-helix	trans	-62.1	-39.1	175.5	-169.6	173.5	-176.2	169.1	0	112.7	V190 V191 R196 M309	V190-K194 WeakPolarHBondContact O-CB 3.4Å; V190-K194 PolarHBondContact O-N 2.96Å; V191-K194 PolarHBondContact O-N 3.24Å; K194-R196 PolarHBondContact O-N 3.08Å; K194-M309 HydrophobicContact CB-CE 4.44Å; K194-M309 HydrophobicContact CD-CE 4.03Å
195	Y	86.1	Confident	85.6	Confident	174 Å²	174	78.3 Å²	78.3	68%	0.682	36%	0.364	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.1	7.1	176.6	-73.1	-62.1	0	0	0	114.3	V191 L192 Y193 C197	V191-Y195 HydrophobicContact CG1-CD2 3.5Å; V191-Y195 HydrophobicContact CG1-CE2 3.34Å; V191-Y195 WeakPolarHBondContact O-CD2 3.08Å; V191-Y195 PolarHBondContact O-N 2.92Å; L192-Y195 PolarHBondContact O-N 3.08Å; Y193-Y195 VanDerWaalsContact C-N 3.34Å; Y193-Y195 PolarHBondContact O-N 2.89Å; Y195-C197 PolarHBondContact O-N 3Å
196	R	82.7	Confident	85.7	Confident	160 Å²	160	76.1 Å²	76.1	60%	0.604	35%	0.353	S	S	*	.	T	Hydrogen-bonded Turn	trans	55.6	30.8	-179.9	-64.1	-173	171.7	-179.8	-1.7	113.3	L192 Y193 K194 Y198	L192-R196 PolarHBondContact O-N 3.22Å; Y193-R196 PolarHBondContact O-N 3.01Å; Y193-R196 VanDerWaalsContact O-N 3.1Å; K194-R196 PolarHBondContact O-N 3.08Å; R196-Y198 HydrophobicContact CB-CD2 4.07Å; R196-Y198 HydrophobicContact CB-CE2 3.66Å; R196-Y198 HydrophobicContact CG-CE2 3.88Å; R196-Y198 VanDerWaalsContact O-CD2 3.27Å; R196-Y198 WeakPolarHBondContact O-CD2 3.36Å; R196-Y198 PolarHBondContact O-N 2.71Å
197	C	83.4	Confident	85.8	Confident	50 Å²	50	79.9 Å²	79.9	34%	0.338	37%	0.37	S	S	.	.			trans	-78.7	50	177.2	-62.5	0	0	0	0	112.1	L192 Y195 K199 F200 I201	L192-C197 HydrophobicContact CD2-CB 3.98Å; L192-C197 PolarHBondContact O-N 3.38Å; L192-C197 VanDerWaalsContact O-N 3.1Å; Y195-C197 PolarHBondContact O-N 3Å; C197-K199 VanDerWaalsContact C-N 3.3Å; C197-K199 PolarHBondContact O-N 2.92Å; C197-F200 HydrophobicContact CB-CB 4.21Å; C197-F200 WeakPolarHBondContact O-CB 3.5Å; C197-F200 PolarHBondContact O-N 2.72Å; C197-I201 PolarHBondContact O-N 2.87Å
198	Y	81.5	Confident	86	Confident	70 Å²	70	78.8 Å²	78.8	28%	0.275	37%	0.369	S	S	.	.	H	α-helix	trans	-57.3	-38.7	-172.2	-64.1	-76.8	0	0	0	113.6	Y193 R196 F200 I201 H202 R317 E319	Y193-Y198 HydrophobicContact CE2-CE1 4.17Å; R196-Y198 HydrophobicContact CB-CD2 4.07Å; R196-Y198 HydrophobicContact CB-CE2 3.66Å; R196-Y198 HydrophobicContact CG-CE2 3.88Å; R196-Y198 VanDerWaalsContact O-CD2 3.27Å; R196-Y198 WeakPolarHBondContact O-CD2 3.36Å; R196-Y198 PolarHBondContact O-N 2.71Å; Y198-F200 VanDerWaalsContact C-N 3.27Å; Y198-F200 PolarHBondContact O-N 3.46Å; Y198-I201 PolarHBondContact O-N 3.34Å; Y198-H202 VanDerWaalsContact O-CB 3.24Å; Y198-H202 WeakPolarHBondContact O-CB 3.44Å; Y198-H202 PolarHBondContact O-N 3.2Å; Y198-R317 PolarHBondContact OH-NH1 3.45Å; Y198-E319 WeakPolarHBondContact CE1-OE2 3.47Å; Y198-E319 PolarHBondContact OH-OE1 3.42Å; Y198-E319 VanDerWaalsContact OH-OE1 3.05Å; Y198-E319 PolarHBondContact OH-OE2 2.96Å; Y198-E319 VanDerWaalsContact OH-OE2 3.08Å
199	K	87.1	Confident	86	Confident	197 Å²	197	75 Å²	75	86%	0.857	35%	0.354	S	S	*	.	H	α-helix	trans	-60	-39	176.1	-69.7	-177	175.7	169.8	0	112.2	C197 G203	C197-K199 VanDerWaalsContact C-N 3.3Å; C197-K199 PolarHBondContact O-N 2.92Å; K199-G203 PolarHBondContact O-N 2.95Å
200	F	88.7	Confident	86.4	Confident	96 Å²	96	76.1 Å²	76.1	42%	0.421	36%	0.36	S	S	.	.	H	α-helix	trans	-72.4	-43.8	178.2	-174.1	-90.3	0	0	0	111.2	F188 L192 C197 Y198 G203 W204	F188-F200 HydrophobicContact CE1-CE1 4.15Å; F188-F200 HydrophobicContact CZ-CE1 4.23Å; L192-F200 HydrophobicContact CD1-CD1 3.53Å; L192-F200 HydrophobicContact CD1-CE1 3.5Å; L192-F200 VanDerWaalsContact CD1-CE1 3.5Å; L192-F200 HydrophobicContact CD2-CD1 3.92Å; L192-F200 HydrophobicContact CD2-CE1 4.33Å; L192-F200 HydrophobicContact CG-CD1 4.34Å; C197-F200 HydrophobicContact CB-CB 4.21Å; C197-F200 WeakPolarHBondContact O-CB 3.5Å; C197-F200 PolarHBondContact O-N 2.72Å; Y198-F200 VanDerWaalsContact C-N 3.27Å; Y198-F200 PolarHBondContact O-N 3.46Å; F200-G203 PolarHBondContact O-N 2.94Å; F200-W204 HydrophobicContact CE1-CD2 4.46Å; F200-W204 AromaticContact CE1-CE3 3.62Å; F200-W204 HydrophobicContact CE1-CE3 3.62Å; F200-W204 HydrophobicContact CE1-CZ3 4.24Å; F200-W204 AromaticContact CZ-CE3 3.66Å; F200-W204 HydrophobicContact CZ-CE3 3.66Å; F200-W204 HydrophobicContact CZ-CZ3 4.08Å; F200-W204 VanDerWaalsContact O-CB 3.23Å; F200-W204 WeakPolarHBondContact O-CB 3.41Å; F200-W204 PolarHBondContact O-N 3.36Å
201	I	86.1	Confident	86.7	Confident	5 Å²	5	80 Å²	80	3%	0.026	38%	0.378	C	S	.	.	H	α-helix	trans	-62.3	-47.8	178.4	-60.4	168.5	0	0	0	110.5	L192 Y193 C197 Y198 W204 L205 F322	L192-I201 HydrophobicContact CB-CD1 4.19Å; L192-I201 HydrophobicContact CB-CG1 4.03Å; Y193-I201 HydrophobicContact CD2-CD1 4.13Å; C197-I201 PolarHBondContact O-N 2.87Å; Y198-I201 PolarHBondContact O-N 3.34Å; I201-W204 PolarHBondContact O-N 3.48Å; I201-L205 HydrophobicContact CG2-CD1 4.13Å; I201-L205 HydrophobicContact CG2-CG 4.37Å; I201-L205 WeakPolarHBondContact O-CB 3.49Å; I201-L205 WeakPolarHBondContact O-CG 3.39Å; I201-L205 PolarHBondContact O-N 2.92Å; I201-F322 HydrophobicContact CB-CZ 4.48Å; I201-F322 HydrophobicContact CG2-CD1 4.47Å; I201-F322 HydrophobicContact CG2-CE1 3.6Å; I201-F322 HydrophobicContact CG2-CE2 4.19Å; I201-F322 HydrophobicContact CG2-CZ 3.45Å; I201-F322 VanDerWaalsContact CG2-CZ 3.45Å
202	H	83	Confident	86.9	Confident	103 Å²	103	78 Å²	78	48%	0.477	37%	0.365	S	S	.	.	H	α-helix	trans	-62.7	-45.3	179.1	-167.1	-85.5	0	0	0	111.6	Y198 L205 I206	Y198-H202 VanDerWaalsContact O-CB 3.24Å; Y198-H202 WeakPolarHBondContact O-CB 3.44Å; Y198-H202 PolarHBondContact O-N 3.2Å; H202-L205 PolarHBondContact O-N 3.43Å; H202-I206 WeakPolarHBondContact CE1-CD1 3.23Å; H202-I206 VanDerWaalsContact ND1-CD1 3.31Å; H202-I206 WeakPolarHBondContact ND1-CD1 3.38Å; H202-I206 WeakPolarHBondContact O-CB 3.42Å; H202-I206 WeakPolarHBondContact O-CG1 3.49Å; H202-I206 PolarHBondContact O-N 2.89Å
203	G	88.8	Confident	87.2	Confident	33 Å²	33	76.7 Å²	76.7	34%	0.34	36%	0.358	S	S	.	.	H	α-helix	trans	-62.2	-42	175	0	0	0	0	0	112.9	K199 F200 M207	K199-G203 PolarHBondContact O-N 2.95Å; F200-G203 PolarHBondContact O-N 2.94Å; G203-M207 WeakPolarHBondContact O-CB 3.26Å; G203-M207 VanDerWaalsContact O-CG 3.25Å; G203-M207 WeakPolarHBondContact O-CG 3.29Å; G203-M207 PolarHBondContact O-N 2.86Å
204	W	88.4	Confident	87.9	Confident	121 Å²	121	78 Å²	78	46%	0.458	37%	0.365	S	S	.	.	H	α-helix	trans	-63.2	-47.5	176.4	-179.3	-67.8	0	0	0	111.7	F188 F200 I201 M207 S208	F188-W204 HydrophobicContact CE1-CH2 4.35Å; F188-W204 HydrophobicContact CE1-CZ3 4.08Å; F200-W204 HydrophobicContact CE1-CD2 4.46Å; F200-W204 AromaticContact CE1-CE3 3.62Å; F200-W204 HydrophobicContact CE1-CE3 3.62Å; F200-W204 HydrophobicContact CE1-CZ3 4.24Å; F200-W204 AromaticContact CZ-CE3 3.66Å; F200-W204 HydrophobicContact CZ-CE3 3.66Å; F200-W204 HydrophobicContact CZ-CZ3 4.08Å; F200-W204 VanDerWaalsContact O-CB 3.23Å; F200-W204 WeakPolarHBondContact O-CB 3.41Å; F200-W204 PolarHBondContact O-N 3.36Å; I201-W204 PolarHBondContact O-N 3.48Å; W204-M207 PolarHBondContact O-N 3.48Å; W204-S208 WeakPolarHBondContact O-CB 3.24Å; W204-S208 PolarHBondContact O-N 2.99Å
205	L	85.1	Confident	88.4	Confident	24 Å²	24	74.8 Å²	74.8	13%	0.126	35%	0.354	C	S	.	.	H	α-helix	trans	-63.8	-41.4	179.6	-74.4	-176.6	0	0	0	112	I201 H202 S208 S209 F322 L325	I201-L205 HydrophobicContact CG2-CD1 4.13Å; I201-L205 HydrophobicContact CG2-CG 4.37Å; I201-L205 WeakPolarHBondContact O-CB 3.49Å; I201-L205 WeakPolarHBondContact O-CG 3.39Å; I201-L205 PolarHBondContact O-N 2.92Å; H202-L205 PolarHBondContact O-N 3.43Å; L205-S208 PolarHBondContact O-N 2.95Å; L205-S209 WeakPolarHBondContact O-CB 3.45Å; L205-S209 PolarHBondContact O-N 2.96Å; L205-S209 PolarHBondContact O-OG 3.21Å; L205-F322 HydrophobicContact CD1-CB 3.87Å; L205-F322 HydrophobicContact CD1-CD1 3.43Å; L205-F322 VanDerWaalsContact CD1-CD1 3.43Å; L205-F322 HydrophobicContact CD1-CD2 4.29Å; L205-F322 HydrophobicContact CD1-CE1 4.04Å; L205-F322 HydrophobicContact CD1-CG 3.59Å; L205-L325 HydrophobicContact CD1-CD1 4.31Å; L205-L325 HydrophobicContact CD2-CD1 4.26Å
206	I	89.9	Confident	88.7	Confident	50 Å²	50	68 Å²	68	26%	0.256	33%	0.328	S	S	.	.	H	α-helix	trans	-61.7	-45.7	172.6	-74.1	177.6	0	0	0	110.9	H202 S208 S209 L210 M249 H253	H202-I206 WeakPolarHBondContact CE1-CD1 3.23Å; H202-I206 VanDerWaalsContact ND1-CD1 3.31Å; H202-I206 WeakPolarHBondContact ND1-CD1 3.38Å; H202-I206 WeakPolarHBondContact O-CB 3.42Å; H202-I206 WeakPolarHBondContact O-CG1 3.49Å; H202-I206 PolarHBondContact O-N 2.89Å; I206-S208 VanDerWaalsContact C-N 3.35Å; I206-S208 PolarHBondContact O-N 3.41Å; I206-S209 WeakPolarHBondContact CA-OG 3.48Å; I206-S209 PolarHBondContact O-N 3.42Å; I206-S209 PolarHBondContact O-OG 3.39Å; I206-L210 WeakPolarHBondContact O-CB 3.45Å; I206-L210 PolarHBondContact O-N 2.97Å; I206-M249 HydrophobicContact CB-CE 4.45Å; I206-M249 HydrophobicContact CG2-CE 3.82Å; I206-H253 VanDerWaalsContact CG1-CD2 3.42Å; I206-H253 WeakPolarHBondContact CG1-CD2 3.19Å
207	M	90.5	Very high	89.3	Confident	121 Å²	121	60.6 Å²	60.6	60%	0.596	30%	0.301	S	S	*	.	H	α-helix	trans	-65.3	-39.6	179.4	-77.1	-61.8	-59.3	0	0	112.2	G203 W204 M211	G203-M207 WeakPolarHBondContact O-CB 3.26Å; G203-M207 VanDerWaalsContact O-CG 3.25Å; G203-M207 WeakPolarHBondContact O-CG 3.29Å; G203-M207 PolarHBondContact O-N 2.86Å; W204-M207 PolarHBondContact O-N 3.48Å; M207-M211 WeakPolarHBondContact O-CB 3.41Å; M207-M211 PolarHBondContact O-N 3.11Å
208	S	89.5	Confident	89.8	Confident	59 Å²	59	63.5 Å²	63.5	41%	0.413	31%	0.305	S	S	.	.	H	α-helix	trans	-64.8	-46.8	177.7	-173.4	0	0	0	0	111.4	W204 L205 I206 M211 L212	W204-S208 WeakPolarHBondContact O-CB 3.24Å; W204-S208 PolarHBondContact O-N 2.99Å; L205-S208 PolarHBondContact O-N 2.95Å; I206-S208 VanDerWaalsContact C-N 3.35Å; I206-S208 PolarHBondContact O-N 3.41Å; S208-M211 PolarHBondContact O-N 3.46Å; S208-L212 VanDerWaalsContact O-CB 3.29Å; S208-L212 WeakPolarHBondContact O-CB 3.38Å; S208-L212 PolarHBondContact O-N 3.2Å
209	S	89.2	Confident	90.4	Very high	10 Å²	10	62.6 Å²	62.6	7%	0.07	31%	0.305	C	S	.	.	H	α-helix	trans	-68.4	-39.2	178.4	52.7	0	0	0	0	112.5	L205 I206 L212 L213 M249 H253	L205-S209 WeakPolarHBondContact O-CB 3.45Å; L205-S209 PolarHBondContact O-N 2.96Å; L205-S209 PolarHBondContact O-OG 3.21Å; I206-S209 WeakPolarHBondContact CA-OG 3.48Å; I206-S209 PolarHBondContact O-N 3.42Å; I206-S209 PolarHBondContact O-OG 3.39Å; S209-L212 PolarHBondContact O-N 3.48Å; S209-L213 WeakPolarHBondContact O-CB 3.43Å; S209-L213 PolarHBondContact O-N 3.1Å; S209-M249 WeakPolarHBondContact OG-CE 3.39Å; S209-H253 PolarHBondContact OG-CE1 2.91Å; S209-H253 PolarHBondContact OG-NE2 3.28Å
210	L	92.6	Very high	90.8	Very high	71 Å²	71	55.6 Å²	55.6	37%	0.372	27%	0.273	S	S	.	.	H	α-helix	trans	-61.7	-49.4	173.7	-173	163	0	0	0	110.5	I206 L212 L213 F214 M249	I206-L210 WeakPolarHBondContact O-CB 3.45Å; I206-L210 PolarHBondContact O-N 2.97Å; L210-L212 PolarHBondContact O-N 3.1Å; L210-L213 PolarHBondContact O-N 3.45Å; L210-F214 HydrophobicContact CD2-CD2 4.03Å; L210-F214 HydrophobicContact CG-CD2 3.86Å; L210-F214 HydrophobicContact CG-CE2 4.02Å; L210-F214 WeakPolarHBondContact O-CB 3.31Å; L210-F214 VanDerWaalsContact O-CD2 3.3Å; L210-F214 WeakPolarHBondContact O-CD2 3.43Å; L210-F214 PolarHBondContact O-N 2.88Å; L210-M249 HydrophobicContact CB-CE 4.17Å; L210-M249 HydrophobicContact CB-SD 4.02Å
211	M	91.2	Very high	91.1	Very high	93 Å²	93	52.8 Å²	52.8	46%	0.458	26%	0.263	S	S	.	.	H	α-helix	trans	-57.1	-44.6	176.7	-168.7	-161	80.3	0	0	110.3	M207 S208 L215 F216	M207-M211 WeakPolarHBondContact O-CB 3.41Å; M207-M211 PolarHBondContact O-N 3.11Å; S208-M211 PolarHBondContact O-N 3.46Å; M211-L215 HydrophobicContact CG-CB 4.43Å; M211-L215 HydrophobicContact CG-CD2 4.2Å; M211-L215 WeakPolarHBondContact O-CA 3.34Å; M211-L215 WeakPolarHBondContact O-CB 3.4Å; M211-L215 PolarHBondContact O-N 2.96Å; M211-F216 HydrophobicContact CE-CE2 3.81Å; M211-F216 HydrophobicContact CE-CZ 4.19Å
212	L	90.5	Very high	91.5	Very high	15 Å²	15	53.4 Å²	53.4	8%	0.079	27%	0.27	C	S	.	.	I	π-helix	trans	-65.1	-52.6	-177.4	-168.9	170.9	0	0	0	111.8	S208 S209 L210 F216 I268 L271 M272	S208-L212 VanDerWaalsContact O-CB 3.29Å; S208-L212 WeakPolarHBondContact O-CB 3.38Å; S208-L212 PolarHBondContact O-N 3.2Å; S209-L212 PolarHBondContact O-N 3.48Å; L210-L212 PolarHBondContact O-N 3.1Å; L212-F216 HydrophobicContact CB-CD2 4.22Å; L212-F216 HydrophobicContact CG-CD2 3.95Å; L212-F216 HydrophobicContact CG-CE2 4.45Å; L212-F216 WeakPolarHBondContact O-CB 3.47Å; L212-F216 PolarHBondContact O-N 3.44Å; L212-I268 HydrophobicContact CD1-CG2 3.78Å; L212-I268 HydrophobicContact CD2-CB 4.25Å; L212-I268 HydrophobicContact CD2-CG1 3.94Å; L212-I268 HydrophobicContact CD2-CG2 3.98Å; L212-L271 HydrophobicContact CD2-CB 4.31Å; L212-L271 HydrophobicContact CD2-CD1 4.34Å; L212-M272 HydrophobicContact CD1-CG 3.55Å; L212-M272 HydrophobicContact CD1-SD 3.45Å; L212-M272 WeakPolarHBondContact CD1-SD 3.46Å; L212-M272 HydrophobicContact CG-CG 4.27Å; L212-M272 HydrophobicContact CG-SD 3.96Å
213	L	92.4	Very high	92	Very high	0 Å²	0	49.7 Å²	49.7	0%	0	25%	0.253	C	S	.	.	I	π-helix	trans	-67.4	-35.9	-177.5	-80.8	176	0	0	0	113.7	S209 L210 T217 F244 M249 I252 Y264 I268	S209-L213 WeakPolarHBondContact O-CB 3.43Å; S209-L213 PolarHBondContact O-N 3.1Å; L210-L213 PolarHBondContact O-N 3.45Å; L213-T217 WeakPolarHBondContact O-CB 3.38Å; L213-T217 PolarHBondContact O-OG1 3.38Å; L213-F244 HydrophobicContact CD2-CE1 3.75Å; L213-F244 HydrophobicContact CD2-CZ 4.34Å; L213-M249 HydrophobicContact CD1-CG 4.3Å; L213-M249 HydrophobicContact CD1-SD 4Å; L213-I252 HydrophobicContact CD1-CD1 3.89Å; L213-Y264 HydrophobicContact CD2-CD1 4.24Å; L213-I268 HydrophobicContact CD1-CD1 4.19Å; L213-I268 HydrophobicContact CD2-CD1 3.86Å; L213-I268 HydrophobicContact CD2-CG1 3.66Å; L213-I268 HydrophobicContact CG-CD1 3.9Å; L213-I268 HydrophobicContact CG-CG1 4.15Å
214	F	95.4	Very high	92.3	Very high	41 Å²	41	49.7 Å²	49.7	18%	0.18	25%	0.246	C	C	.	.	I	π-helix	trans	-87.4	-51	-179.5	-73.9	-97.6	0	0	0	111.8	L210 Y218 V241 W242 G245 M249	L210-F214 HydrophobicContact CD2-CD2 4.03Å; L210-F214 HydrophobicContact CG-CD2 3.86Å; L210-F214 HydrophobicContact CG-CE2 4.02Å; L210-F214 WeakPolarHBondContact O-CB 3.31Å; L210-F214 VanDerWaalsContact O-CD2 3.3Å; L210-F214 WeakPolarHBondContact O-CD2 3.43Å; L210-F214 PolarHBondContact O-N 2.88Å; F214-Y218 VanDerWaalsContact O-CB 3.24Å; F214-Y218 WeakPolarHBondContact O-CB 3.33Å; F214-Y218 PolarHBondContact O-N 3.24Å; F214-V241 HydrophobicContact CD1-CG1 4.25Å; F214-W242 AromaticContact CE1-CE3 3.87Å; F214-W242 HydrophobicContact CE1-CE3 3.87Å; F214-W242 HydrophobicContact CE1-CZ3 4.34Å; F214-G245 VanDerWaalsContact CE2-C 3.49Å; F214-M249 HydrophobicContact CE2-CG 3.96Å
215	L	93.4	Very high	92.6	Very high	78 Å²	78	45.4 Å²	45.4	41%	0.408	23%	0.232	S	C	.	.	I	π-helix	trans	-72.7	-49.5	-172.8	-175.5	66.4	0	0	0	112.2	M211 Y218 I219	M211-L215 HydrophobicContact CG-CB 4.43Å; M211-L215 HydrophobicContact CG-CD2 4.2Å; M211-L215 WeakPolarHBondContact O-CA 3.34Å; M211-L215 WeakPolarHBondContact O-CB 3.4Å; M211-L215 PolarHBondContact O-N 2.96Å; L215-Y218 PolarHBondContact O-N 3.22Å; L215-I219 HydrophobicContact CD1-CD1 4.41Å; L215-I219 HydrophobicContact CG-CD1 4.14Å; L215-I219 WeakPolarHBondContact O-CG1 3.44Å; L215-I219 PolarHBondContact O-N 3.42Å
216	F	93.6	Very high	93	Very high	31 Å²	31	50.8 Å²	50.8	14%	0.136	26%	0.255	C	S	.	.	I	π-helix	trans	-72.4	-32.9	-177.3	-67.2	-61.1	0	0	0	111.9	M211 L212 I219 Y220 V275	M211-F216 HydrophobicContact CE-CE2 3.81Å; M211-F216 HydrophobicContact CE-CZ 4.19Å; L212-F216 HydrophobicContact CB-CD2 4.22Å; L212-F216 HydrophobicContact CG-CD2 3.95Å; L212-F216 HydrophobicContact CG-CE2 4.45Å; L212-F216 WeakPolarHBondContact O-CB 3.47Å; L212-F216 PolarHBondContact O-N 3.44Å; F216-I219 HydrophobicContact CD1-CD1 4.33Å; F216-I219 PolarHBondContact O-N 2.93Å; F216-Y220 WeakPolarHBondContact O-CB 3.27Å; F216-Y220 PolarHBondContact O-N 3.43Å; F216-V275 HydrophobicContact CD1-CG2 3.47Å; F216-V275 VanDerWaalsContact CD1-CG2 3.47Å; F216-V275 HydrophobicContact CD2-CG2 4.22Å; F216-V275 HydrophobicContact CE1-CG1 4.33Å; F216-V275 HydrophobicContact CE1-CG2 3.4Å; F216-V275 HydrophobicContact CE2-CG2 4.19Å; F216-V275 HydrophobicContact CG-CG2 3.91Å; F216-V275 HydrophobicContact CZ-CG1 4.23Å; F216-V275 HydrophobicContact CZ-CG2 3.79Å
217	T	94.8	Very high	93.2	Very high	5 Å²	5	51.3 Å²	51.3	3%	0.031	26%	0.26	C	S	.	.	H	α-helix	trans	-65	-41.7	172.1	-55.2	0	0	0	0	111.7	L213 I219 Y220 L221 F244	L213-T217 WeakPolarHBondContact O-CB 3.38Å; L213-T217 PolarHBondContact O-OG1 3.38Å; T217-I219 PolarHBondContact O-N 3.35Å; T217-Y220 PolarHBondContact O-N 3.35Å; T217-L221 HydrophobicContact CG2-CD1 3.39Å; T217-L221 WeakPolarHBondContact O-CD1 3.49Å; T217-L221 PolarHBondContact O-N 2.89Å; T217-F244 HydrophobicContact CG2-CD1 3.56Å; T217-F244 HydrophobicContact CG2-CE1 3.77Å; T217-F244 HydrophobicContact CG2-CG 4.26Å; T217-F244 VanDerWaalsContact OG1-CE1 3.3Å; T217-F244 WeakPolarHBondContact OG1-CE1 3.47Å
218	Y	95.2	Very high	93.4	Very high	111 Å²	111	52.6 Å²	52.6	44%	0.435	26%	0.259	S	S	.	.	H	α-helix	trans	-58.3	-46.7	173.3	169.2	-97.6	0	0	0	111.9	F214 L215 G222 L237	F214-Y218 VanDerWaalsContact O-CB 3.24Å; F214-Y218 WeakPolarHBondContact O-CB 3.33Å; F214-Y218 PolarHBondContact O-N 3.24Å; L215-Y218 PolarHBondContact O-N 3.22Å; Y218-G222 PolarHBondContact O-N 3.06Å; Y218-L237 HydrophobicContact CD2-CD2 4.02Å; Y218-L237 HydrophobicContact CD2-CG 4.41Å; Y218-L237 HydrophobicContact CE2-CD2 3.63Å; Y218-L237 HydrophobicContact CE2-CG 4.43Å
219	I	93.4	Very high	93.6	Very high	51 Å²	51	56.9 Å²	56.9	26%	0.262	28%	0.277	S	S	.	.	H	α-helix	trans	-63.1	-45.6	176.5	-64.2	165.8	0	0	0	110.2	L215 F216 T217 G222 E223	L215-I219 HydrophobicContact CD1-CD1 4.41Å; L215-I219 HydrophobicContact CG-CD1 4.14Å; L215-I219 WeakPolarHBondContact O-CG1 3.44Å; L215-I219 PolarHBondContact O-N 3.42Å; F216-I219 HydrophobicContact CD1-CD1 4.33Å; F216-I219 PolarHBondContact O-N 2.93Å; T217-I219 PolarHBondContact O-N 3.35Å; I219-G222 PolarHBondContact O-N 2.85Å; I219-E223 HydrophobicContact CG2-CG 4.45Å; I219-E223 WeakPolarHBondContact O-CG 3.48Å; I219-E223 PolarHBondContact O-N 2.83Å
220	Y	95	Very high	93.9	Very high	49 Å²	49	60.2 Å²	60.2	19%	0.192	30%	0.297	C	S	.	.	H	α-helix	trans	-59.3	-54.5	-179.9	173.3	-100.6	0	0	0	112	T138 Y145 F216 T217 G222 E223 V224 L271 L274	T138-Y220 HydrophobicContact CG2-CD2 4.35Å; T138-Y220 HydrophobicContact CG2-CE2 3.63Å; T138-Y220 PolarHBondContact OG1-OH 3.17Å; Y145-Y220 HydrophobicContact CE2-CD2 4.35Å; F216-Y220 WeakPolarHBondContact O-CB 3.27Å; F216-Y220 PolarHBondContact O-N 3.43Å; T217-Y220 PolarHBondContact O-N 3.35Å; Y220-G222 VanDerWaalsContact C-N 3.27Å; Y220-G222 PolarHBondContact O-N 3.34Å; Y220-E223 PolarHBondContact O-N 3.16Å; Y220-V224 HydrophobicContact CD1-CG2 4.36Å; Y220-V224 HydrophobicContact CD2-CG2 4.37Å; Y220-V224 HydrophobicContact CE1-CG2 4.01Å; Y220-V224 HydrophobicContact CE2-CG2 4.03Å; Y220-V224 VanDerWaalsContact O-CG2 3.29Å; Y220-V224 WeakPolarHBondContact O-CG2 3.31Å; Y220-V224 PolarHBondContact O-N 3.03Å; Y220-L271 HydrophobicContact CD2-CD2 4.24Å; Y220-L271 HydrophobicContact CG-CD2 3.98Å; Y220-L274 HydrophobicContact CD2-CD1 4.15Å; Y220-L274 HydrophobicContact CE2-CD1 4.14Å
221	L	94.9	Very high	93.9	Very high	38 Å²	38	62 Å²	62	20%	0.199	32%	0.322	C	S	.	.	H	α-helix	trans	-59.1	-40.1	176	-91.8	110	0	0	0	111.4	T217 E223 V224 L225 L237 T240 V241	T217-L221 HydrophobicContact CG2-CD1 3.39Å; T217-L221 WeakPolarHBondContact O-CD1 3.49Å; T217-L221 PolarHBondContact O-N 2.89Å; L221-E223 PolarHBondContact O-N 2.98Å; L221-V224 PolarHBondContact O-N 3.2Å; L221-L225 WeakPolarHBondContact O-CB 3.36Å; L221-L225 WeakPolarHBondContact O-CG 3.38Å; L221-L225 PolarHBondContact O-N 3.35Å; L221-L237 HydrophobicContact CB-CD1 3.92Å; L221-L237 HydrophobicContact CD2-CD1 4.17Å; L221-T240 HydrophobicContact CD2-CG2 4.06Å; L221-V241 HydrophobicContact CD1-CG2 4.46Å
222	G	93.7	Very high	94	Very high	18 Å²	18	61.2 Å²	61.2	19%	0.186	32%	0.318	C	S	.	.	H	α-helix	trans	-58.7	-44.7	176.5	0	0	0	0	0	113.1	Y218 I219 Y220 K226	Y218-G222 PolarHBondContact O-N 3.06Å; I219-G222 PolarHBondContact O-N 2.85Å; Y220-G222 VanDerWaalsContact C-N 3.27Å; Y220-G222 PolarHBondContact O-N 3.34Å; G222-K226 VanDerWaalsContact O-CG 3.26Å; G222-K226 WeakPolarHBondContact O-CG 3.47Å; G222-K226 PolarHBondContact O-N 3.19Å; G222-K226 VanDerWaalsContact O-N 3.08Å
223	E	94.3	Very high	94.3	Very high	25 Å²	25	64.3 Å²	64.3	12%	0.117	34%	0.335	C	S	.	.	H	α-helix	trans	-73.6	-33.8	178.1	-64.6	-54.3	137.4	0	0	112.8	V142 F144 I219 Y220 L221 K226 T227	V142-E223 HydrophobicContact CG1-CB 3.86Å; F144-E223 HydrophobicContact CB-CB 4.23Å; F144-E223 HydrophobicContact CB-CG 3.97Å; F144-E223 WeakPolarHBondContact CB-OE2 3.27Å; F144-E223 HydrophobicContact CD1-CG 3.72Å; F144-E223 HydrophobicContact CD2-CG 4.09Å; F144-E223 WeakPolarHBondContact CD2-OE2 3.45Å; F144-E223 HydrophobicContact CE1-CG 4.18Å; F144-E223 HydrophobicContact CG-CB 4.43Å; F144-E223 HydrophobicContact CG-CG 3.65Å; I219-E223 HydrophobicContact CG2-CG 4.45Å; I219-E223 WeakPolarHBondContact O-CG 3.48Å; I219-E223 PolarHBondContact O-N 2.83Å; Y220-E223 PolarHBondContact O-N 3.16Å; L221-E223 PolarHBondContact O-N 2.98Å; E223-K226 IonicContact OE1-NZ 2.71Å; E223-K226 PolarHBondContact OE1-NZ 2.81Å; E223-K226 IonicContact OE2-NZ 3.88Å; E223-T227 WeakPolarHBondContact O-CB 3.49Å; E223-T227 PolarHBondContact O-N 3.01Å; E223-T227 PolarHBondContact O-OG1 3.36Å
224	V	94.8	Very high	94.4	Very high	32 Å²	32	73.2 Å²	73.2	19%	0.194	37%	0.37	C	S	.	.	H	α-helix	trans	-61.2	-51.2	171.5	168.5	0	0	0	0	110.1	V142 Y220 L221 K226 T227 Y228	V142-V224 HydrophobicContact CG2-CG2 3.99Å; Y220-V224 HydrophobicContact CD1-CG2 4.36Å; Y220-V224 HydrophobicContact CD2-CG2 4.37Å; Y220-V224 HydrophobicContact CE1-CG2 4.01Å; Y220-V224 HydrophobicContact CE2-CG2 4.03Å; Y220-V224 VanDerWaalsContact O-CG2 3.29Å; Y220-V224 WeakPolarHBondContact O-CG2 3.31Å; Y220-V224 PolarHBondContact O-N 3.03Å; L221-V224 PolarHBondContact O-N 3.2Å; V224-K226 VanDerWaalsContact C-N 3.33Å; V224-K226 PolarHBondContact O-N 3.39Å; V224-T227 PolarHBondContact O-N 3.13Å; V224-T227 VanDerWaalsContact O-N 3.07Å; V224-Y228 HydrophobicContact CG1-CD2 3.72Å; V224-Y228 HydrophobicContact CG1-CE2 3.87Å; V224-Y228 VanDerWaalsContact O-CD2 3.24Å; V224-Y228 WeakPolarHBondContact O-CD2 3.42Å; V224-Y228 PolarHBondContact O-N 2.83Å
225	L	94.8	Very high	94.4	Very high	31 Å²	31	75.6 Å²	75.6	16%	0.162	39%	0.39	C	S	.	.	H	α-helix	trans	-60.4	-41.1	179.5	-71	167.7	0	0	0	112.3	L221 T227 N229 V230 M232 L237	L221-L225 WeakPolarHBondContact O-CB 3.36Å; L221-L225 WeakPolarHBondContact O-CG 3.38Å; L221-L225 PolarHBondContact O-N 3.35Å; L225-T227 VanDerWaalsContact C-N 3.34Å; L225-N229 WeakPolarHBondContact O-CA 3.43Å; L225-N229 PolarHBondContact O-N 3.37Å; L225-V230 HydrophobicContact CD2-CB 4.1Å; L225-V230 HydrophobicContact CD2-CG1 4.17Å; L225-V230 PolarHBondContact O-N 2.98Å; L225-M232 HydrophobicContact CD1-CB 3.86Å; L225-M232 HydrophobicContact CD1-CG 4.47Å; L225-M232 HydrophobicContact CD1-SD 3.96Å; L225-M232 HydrophobicContact CD2-CB 4.08Å; L225-M232 HydrophobicContact CD2-CE 4.06Å; L225-M232 HydrophobicContact CD2-SD 4.4Å; L225-L237 HydrophobicContact CD1-CD1 4.04Å
226	K	93.6	Very high	94.5	Very high	138 Å²	138	74.6 Å²	74.6	60%	0.6	39%	0.387	S	S	*	.	H	α-helix	trans	-61.7	-41.5	173.3	-74.2	172.6	-169.8	170.7	0	112.2	G222 E223 V224 N229	G222-K226 VanDerWaalsContact O-CG 3.26Å; G222-K226 WeakPolarHBondContact O-CG 3.47Å; G222-K226 PolarHBondContact O-N 3.19Å; G222-K226 VanDerWaalsContact O-N 3.08Å; E223-K226 IonicContact OE1-NZ 2.71Å; E223-K226 PolarHBondContact OE1-NZ 2.81Å; E223-K226 IonicContact OE2-NZ 3.88Å; V224-K226 VanDerWaalsContact C-N 3.33Å; V224-K226 PolarHBondContact O-N 3.39Å; K226-N229 PolarHBondContact O-N 3.22Å
227	T	93.9	Very high	94.6	Very high	60 Å²	60	73.9 Å²	73.9	37%	0.368	38%	0.384	S	S	.	.	H	α-helix	trans	-69.4	-41.7	-177.6	-54.7	0	0	0	0	111.7	S141 E223 V224 L225 N229	S141-T227 WeakPolarHBondContact O-CG2 3.39Å; E223-T227 WeakPolarHBondContact O-CB 3.49Å; E223-T227 PolarHBondContact O-N 3.01Å; E223-T227 PolarHBondContact O-OG1 3.36Å; V224-T227 PolarHBondContact O-N 3.13Å; V224-T227 VanDerWaalsContact O-N 3.07Å; L225-T227 VanDerWaalsContact C-N 3.34Å; T227-N229 PolarHBondContact O-N 3.46Å
228	Y	94.5	Very high	94.6	Very high	148 Å²	148	79 Å²	79	58%	0.58	41%	0.411	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81	0.7	175	-69	-74.3	0	0	0	113.5	V224 V230	V224-Y228 HydrophobicContact CG1-CD2 3.72Å; V224-Y228 HydrophobicContact CG1-CE2 3.87Å; V224-Y228 VanDerWaalsContact O-CD2 3.24Å; V224-Y228 WeakPolarHBondContact O-CD2 3.42Å; V224-Y228 PolarHBondContact O-N 2.83Å; Y228-V230 PolarHBondContact O-N 3.29Å
229	N	95.4	Very high	94.7	Very high	149 Å²	149	78.9 Å²	78.9	80%	0.797	42%	0.417	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.6	38.3	-178.3	-164.5	38.8	0	0	0	113.3	L225 K226 T227	L225-N229 WeakPolarHBondContact O-CA 3.43Å; L225-N229 PolarHBondContact O-N 3.37Å; K226-N229 PolarHBondContact O-N 3.22Å; T227-N229 PolarHBondContact O-N 3.46Å
230	V	94.9	Very high	94.8	Very high	81 Å²	81	79.3 Å²	79.3	49%	0.491	42%	0.422	S	S	.	.			trans	-97.1	119.7	178.8	177.5	0	0	0	0	109.1	L225 Y228 M232	L225-V230 HydrophobicContact CD2-CB 4.1Å; L225-V230 HydrophobicContact CD2-CG1 4.17Å; L225-V230 PolarHBondContact O-N 2.98Å; Y228-V230 PolarHBondContact O-N 3.29Å; V230-M232 PolarHBondContact O-N 2.85Å
231	A	92.6	Very high	94.9	Very high	108 Å²	108	77.4 Å²	77.4	89%	0.893	42%	0.416	S	S	*	.			trans	-78.5	105.8	173.9	0	0	0	0	0	109.9
232	M	93.3	Very high	95	Very high	77 Å²	77	83.2 Å²	83.2	38%	0.379	44%	0.435	S	S	.	.			trans	-109.7	137.3	171.3	-174.2	176.1	-76.6	0	0	109.5	L225 V230 T236 L237	L225-M232 HydrophobicContact CD1-CB 3.86Å; L225-M232 HydrophobicContact CD1-CG 4.47Å; L225-M232 HydrophobicContact CD1-SD 3.96Å; L225-M232 HydrophobicContact CD2-CB 4.08Å; L225-M232 HydrophobicContact CD2-CE 4.06Å; L225-M232 HydrophobicContact CD2-SD 4.4Å; V230-M232 PolarHBondContact O-N 2.85Å; M232-T236 HydrophobicContact CE-CG2 4.36Å; M232-T236 HydrophobicContact CG-CG2 4.03Å; M232-T236 HydrophobicContact SD-CG2 3.96Å; M232-L237 HydrophobicContact SD-CB 4.28Å; M232-L237 HydrophobicContact SD-CD1 4.38Å
233	D	95.5	Very high	95.1	Very high	80 Å²	80	86.5 Å²	86.5	43%	0.428	45%	0.448	S	S	.	.			trans	-74.2	153.1	177.8	63.6	-69.4	0	0	0	112	P235 T236 L237	D233-P235 VanDerWaalsContact OD2-CD 3.25Å; D233-P235 WeakPolarHBondContact OD2-CD 3.39Å; D233-T236 PolarHBondContact O-N 3.31Å; D233-T236 VanDerWaalsContact OD1-CB 3.23Å; D233-T236 WeakPolarHBondContact OD1-CB 3.11Å; D233-T236 PolarHBondContact OD1-OG1 3.48Å; D233-T236 PolarHBondContact OD2-N 2.65Å; D233-T236 PolarHBondContact OD2-OG1 3.28Å; D233-L237 PolarHBondContact O-N 3.43Å
234	Y	94.6	Very high	95.2	Very high	186 Å²	186	87.6 Å²	87.6	73%	0.729	45%	0.453	S	S	*	.	H	α-helix	trans	-60.9	-40.1	-179.5	-65.7	-72	0	0	0	114.3	L237 L238	Y234-L237 PolarHBondContact O-N 3.47Å; Y234-L238 VanDerWaalsContact O-CB 3.27Å; Y234-L238 WeakPolarHBondContact O-CB 3.25Å; Y234-L238 PolarHBondContact O-N 3.09Å
235	P	96.4	Very high	95.3	Very high	92 Å²	92	86.1 Å²	86.1	60%	0.597	44%	0.444	S	S	*	.	H	α-helix	trans	-57.8	-48.5	174.4	-26	33.8	0	0	0	113.4	D233 L238 L239	D233-P235 VanDerWaalsContact OD2-CD 3.25Å; D233-P235 WeakPolarHBondContact OD2-CD 3.39Å; P235-L238 PolarHBondContact O-N 3.35Å; P235-L239 WeakPolarHBondContact O-CB 3.32Å; P235-L239 PolarHBondContact O-N 3.14Å
236	T	95.8	Very high	95.3	Very high	57 Å²	57	86 Å²	86	35%	0.35	45%	0.448	S	S	.	.	H	α-helix	trans	-60.3	-48.2	176.4	-59.1	0	0	0	0	111.2	M232 D233 L238 L239 T240	M232-T236 HydrophobicContact CE-CG2 4.36Å; M232-T236 HydrophobicContact CG-CG2 4.03Å; M232-T236 HydrophobicContact SD-CG2 3.96Å; D233-T236 PolarHBondContact O-N 3.31Å; D233-T236 VanDerWaalsContact OD1-CB 3.23Å; D233-T236 WeakPolarHBondContact OD1-CB 3.11Å; D233-T236 PolarHBondContact OD1-OG1 3.48Å; D233-T236 PolarHBondContact OD2-N 2.65Å; D233-T236 PolarHBondContact OD2-OG1 3.28Å; T236-L238 VanDerWaalsContact C-N 3.34Å; T236-L238 PolarHBondContact O-N 2.88Å; T236-L239 PolarHBondContact O-N 3.01Å; T236-T240 PolarHBondContact O-N 2.76Å; T236-T240 PolarHBondContact O-OG1 2.97Å; T236-T240 VanDerWaalsContact O-OG1 3.05Å
237	L	95.1	Very high	95.4	Very high	15 Å²	15	82.3 Å²	82.3	8%	0.079	44%	0.436	C	S	.	.	H	α-helix	trans	-59.3	-44.4	178.3	-178.6	66.1	0	0	0	112.1	Y218 L221 L225 M232 D233 Y234 T240 V241	Y218-L237 HydrophobicContact CD2-CD2 4.02Å; Y218-L237 HydrophobicContact CD2-CG 4.41Å; Y218-L237 HydrophobicContact CE2-CD2 3.63Å; Y218-L237 HydrophobicContact CE2-CG 4.43Å; L221-L237 HydrophobicContact CB-CD1 3.92Å; L221-L237 HydrophobicContact CD2-CD1 4.17Å; L225-L237 HydrophobicContact CD1-CD1 4.04Å; M232-L237 HydrophobicContact SD-CB 4.28Å; M232-L237 HydrophobicContact SD-CD1 4.38Å; D233-L237 PolarHBondContact O-N 3.43Å; Y234-L237 PolarHBondContact O-N 3.47Å; L237-T240 PolarHBondContact O-N 3.39Å; L237-V241 HydrophobicContact CD1-CG2 4.31Å; L237-V241 WeakPolarHBondContact O-CB 3.2Å; L237-V241 VanDerWaalsContact O-CG2 3.3Å; L237-V241 WeakPolarHBondContact O-CG2 3.08Å; L237-V241 PolarHBondContact O-N 3.07Å
238	L	95.5	Very high	95.4	Very high	114 Å²	114	79.5 Å²	79.5	60%	0.597	42%	0.419	S	S	*	.	H	α-helix	trans	-64	-42.5	178.4	-178.1	65.3	0	0	0	111.2	Y234 P235 T236 W242	Y234-L238 VanDerWaalsContact O-CB 3.27Å; Y234-L238 WeakPolarHBondContact O-CB 3.25Å; Y234-L238 PolarHBondContact O-N 3.09Å; P235-L238 PolarHBondContact O-N 3.35Å; T236-L238 VanDerWaalsContact C-N 3.34Å; T236-L238 PolarHBondContact O-N 2.88Å; L238-W242 WeakPolarHBondContact O-CB 3.27Å; L238-W242 PolarHBondContact O-N 2.99Å
239	L	96.9	Very high	95.3	Very high	108 Å²	108	73.7 Å²	73.7	57%	0.565	40%	0.398	S	S	*	.	H	α-helix	trans	-63.6	-43.8	176.8	-175.2	66	0	0	0	111	P235 T236 W242 N243	P235-L239 WeakPolarHBondContact O-CB 3.32Å; P235-L239 PolarHBondContact O-N 3.14Å; T236-L239 PolarHBondContact O-N 3.01Å; L239-W242 PolarHBondContact O-N 3.42Å; L239-N243 PolarHBondContact O-N 3.5Å; L239-N243 PolarHBondContact O-ND2 3.2Å
240	T	95.9	Very high	95.1	Very high	59 Å²	59	70.2 Å²	70.2	36%	0.362	38%	0.381	S	S	.	.	H	α-helix	trans	-62.1	-49.1	176.9	-60	0	0	0	0	111.5	L221 T236 L237 W242 N243 F244	L221-T240 HydrophobicContact CD2-CG2 4.06Å; T236-T240 PolarHBondContact O-N 2.76Å; T236-T240 PolarHBondContact O-OG1 2.97Å; T236-T240 VanDerWaalsContact O-OG1 3.05Å; L237-T240 PolarHBondContact O-N 3.39Å; T240-W242 VanDerWaalsContact C-N 3.32Å; T240-W242 PolarHBondContact O-N 3.25Å; T240-N243 PolarHBondContact O-N 2.8Å; T240-F244 WeakPolarHBondContact O-CB 3.11Å; T240-F244 PolarHBondContact O-N 3.41Å
241	V	96.6	Very high	94.8	Very high	9 Å²	9	66.5 Å²	66.5	6%	0.055	36%	0.359	C	S	.	.	H	α-helix	trans	-64.8	-38.1	178.5	173	0	0	0	0	111.2	F214 L221 L237 G245	F214-V241 HydrophobicContact CD1-CG1 4.25Å; L221-V241 HydrophobicContact CD1-CG2 4.46Å; L237-V241 HydrophobicContact CD1-CG2 4.31Å; L237-V241 WeakPolarHBondContact O-CB 3.2Å; L237-V241 VanDerWaalsContact O-CG2 3.3Å; L237-V241 WeakPolarHBondContact O-CG2 3.08Å; L237-V241 PolarHBondContact O-N 3.07Å; V241-G245 PolarHBondContact O-N 3.18Å
242	W	96.6	Very high	94.6	Very high	161 Å²	161	61.6 Å²	61.6	61%	0.61	32%	0.318	S	S	*	.	H	α-helix	trans	-63.3	-47.8	176.5	179.3	-94.2	0	0	0	112	F214 L238 L239 T240 G245 A246	F214-W242 AromaticContact CE1-CE3 3.87Å; F214-W242 HydrophobicContact CE1-CE3 3.87Å; F214-W242 HydrophobicContact CE1-CZ3 4.34Å; L238-W242 WeakPolarHBondContact O-CB 3.27Å; L238-W242 PolarHBondContact O-N 2.99Å; L239-W242 PolarHBondContact O-N 3.42Å; T240-W242 VanDerWaalsContact C-N 3.32Å; T240-W242 PolarHBondContact O-N 3.25Å; W242-G245 PolarHBondContact O-N 2.96Å; W242-A246 WeakPolarHBondContact O-CB 3.42Å; W242-A246 PolarHBondContact O-N 3.12Å
243	N	96.6	Very high	94.3	Very high	86 Å²	86	60.2 Å²	60.2	46%	0.46	31%	0.31	S	S	.	.	H	α-helix	trans	-61.1	-48.7	177.6	-80.7	-75.3	0	0	0	111.3	L239 T240 V247	L239-N243 PolarHBondContact O-N 3.5Å; L239-N243 PolarHBondContact O-ND2 3.2Å; T240-N243 PolarHBondContact O-N 2.8Å; N243-V247 VanDerWaalsContact O-CB 3.29Å; N243-V247 WeakPolarHBondContact O-CB 3.37Å; N243-V247 WeakPolarHBondContact O-CG2 3.29Å; N243-V247 PolarHBondContact O-N 2.65Å
244	F	96.4	Very high	93.9	Very high	49 Å²	49	65.8 Å²	65.8	22%	0.215	33%	0.326	C	S	.	.	H	α-helix	trans	-61.2	-48.2	177.8	179.9	-93.6	0	0	0	112.2	L213 T217 T240 G248 Y264 M267	L213-F244 HydrophobicContact CD2-CE1 3.75Å; L213-F244 HydrophobicContact CD2-CZ 4.34Å; T217-F244 HydrophobicContact CG2-CD1 3.56Å; T217-F244 HydrophobicContact CG2-CE1 3.77Å; T217-F244 HydrophobicContact CG2-CG 4.26Å; T217-F244 VanDerWaalsContact OG1-CE1 3.3Å; T217-F244 WeakPolarHBondContact OG1-CE1 3.47Å; T240-F244 WeakPolarHBondContact O-CB 3.11Å; T240-F244 PolarHBondContact O-N 3.41Å; F244-G248 PolarHBondContact O-N 3.49Å; F244-Y264 HydrophobicContact CD1-CE1 4.39Å; F244-Y264 AromaticContact CD2-CE1 3.79Å; F244-Y264 HydrophobicContact CD2-CE1 3.79Å; F244-Y264 HydrophobicContact CE1-CE1 4.2Å; F244-Y264 HydrophobicContact CE2-CD1 4.17Å; F244-Y264 AromaticContact CE2-CE1 3.55Å; F244-Y264 HydrophobicContact CE2-CE1 3.55Å; F244-Y264 HydrophobicContact CG-CE1 4.22Å; F244-Y264 HydrophobicContact CZ-CD1 4.06Å; F244-Y264 AromaticContact CZ-CE1 3.78Å; F244-Y264 HydrophobicContact CZ-CE1 3.78Å; F244-Y264 WeakPolarHBondContact O-CE1 3.49Å; F244-Y264 PolarHBondContact O-OH 3.32Å; F244-M267 HydrophobicContact CZ-CB 4.31Å
245	G	95.8	Very high	93.3	Very high	0 Å²	0	65.4 Å²	65.4	0%	0	33%	0.328	C	S	.	.	H	α-helix	trans	-67.2	-45.1	-178.2	0	0	0	0	0	112.9	F214 V241 W242 G248 M249	F214-G245 VanDerWaalsContact CE2-C 3.49Å; V241-G245 PolarHBondContact O-N 3.18Å; W242-G245 PolarHBondContact O-N 2.96Å; G245-G248 PolarHBondContact O-N 3.2Å; G245-M249 WeakPolarHBondContact O-CB 3.45Å; G245-M249 VanDerWaalsContact O-CG 3.26Å; G245-M249 WeakPolarHBondContact O-CG 3.47Å; G245-M249 PolarHBondContact O-N 3.47Å
246	A	95.3	Very high	92.6	Very high	30 Å²	30	61.6 Å²	61.6	25%	0.248	31%	0.305	C	S	.	.	H	α-helix	trans	-67	-46.3	-179.3	0	0	0	0	0	111.6	W242 G248 M249 V250	W242-A246 WeakPolarHBondContact O-CB 3.42Å; W242-A246 PolarHBondContact O-N 3.12Å; A246-G248 VanDerWaalsContact C-N 3.34Å; A246-G248 PolarHBondContact O-N 3.44Å; A246-M249 PolarHBondContact O-N 3.37Å; A246-V250 WeakPolarHBondContact O-CG2 3.36Å; A246-V250 PolarHBondContact O-N 3.01Å
247	V	95.5	Very high	92.3	Very high	60 Å²	60	62.3 Å²	62.3	36%	0.364	31%	0.311	S	S	.	.	H	α-helix	trans	-63.1	-42.7	176.1	176	0	0	0	0	110.1	N243 M249 V250 C251 L260 Y264	N243-V247 VanDerWaalsContact O-CB 3.29Å; N243-V247 WeakPolarHBondContact O-CB 3.37Å; N243-V247 WeakPolarHBondContact O-CG2 3.29Å; N243-V247 PolarHBondContact O-N 2.65Å; V247-M249 PolarHBondContact O-N 3.43Å; V247-V250 PolarHBondContact O-N 3.34Å; V247-C251 WeakPolarHBondContact O-CB 3.04Å; V247-C251 PolarHBondContact O-N 3.28Å; V247-C251 PolarHBondContact O-SG 3.31Å; V247-L260 HydrophobicContact CG1-CD2 4.04Å; V247-Y264 HydrophobicContact CB-CE2 4.5Å; V247-Y264 WeakPolarHBondContact CB-OH 3.37Å; V247-Y264 HydrophobicContact CG1-CE2 3.8Å; V247-Y264 WeakPolarHBondContact CG1-OH 3.28Å
248	G	93.4	Very high	91.8	Very high	0 Å²	0	63.2 Å²	63.2	0%	0	32%	0.316	C	S	.	.	H	α-helix	trans	-59.4	-42.8	174.9	0	0	0	0	0	113.3	F244 G245 A246 V250 C251 I252 Y264	F244-G248 PolarHBondContact O-N 3.49Å; G245-G248 PolarHBondContact O-N 3.2Å; A246-G248 VanDerWaalsContact C-N 3.34Å; A246-G248 PolarHBondContact O-N 3.44Å; G248-V250 PolarHBondContact O-N 3.41Å; G248-C251 PolarHBondContact O-N 2.92Å; G248-I252 WeakPolarHBondContact O-CB 3.23Å; G248-I252 WeakPolarHBondContact O-CD1 3.37Å; G248-I252 WeakPolarHBondContact O-CG1 3.38Å; G248-I252 PolarHBondContact O-N 2.69Å; G248-Y264 VanDerWaalsContact CA-CD1 3.5Å
249	M	92.3	Very high	91.5	Very high	27 Å²	27	63.2 Å²	63.2	13%	0.133	32%	0.32	C	S	.	.	H	α-helix	trans	-63.5	-41.8	176.4	-73.6	-55.4	-61.6	0	0	112.4	I206 S209 L210 L213 F214 G245 A246 V247 H253	I206-M249 HydrophobicContact CB-CE 4.45Å; I206-M249 HydrophobicContact CG2-CE 3.82Å; S209-M249 WeakPolarHBondContact OG-CE 3.39Å; L210-M249 HydrophobicContact CB-CE 4.17Å; L210-M249 HydrophobicContact CB-SD 4.02Å; L213-M249 HydrophobicContact CD1-CG 4.3Å; L213-M249 HydrophobicContact CD1-SD 4Å; F214-M249 HydrophobicContact CE2-CG 3.96Å; G245-M249 WeakPolarHBondContact O-CB 3.45Å; G245-M249 VanDerWaalsContact O-CG 3.26Å; G245-M249 WeakPolarHBondContact O-CG 3.47Å; G245-M249 PolarHBondContact O-N 3.47Å; A246-M249 PolarHBondContact O-N 3.37Å; V247-M249 PolarHBondContact O-N 3.43Å; M249-H253 PolarHBondContact O-N 3.36Å
250	V	91.8	Very high	91.2	Very high	75 Å²	75	61.2 Å²	61.2	46%	0.455	31%	0.309	S	S	.	.	H	α-helix	trans	-64.5	-46.4	175.1	173.9	0	0	0	0	110.5	A246 V247 G248 I252 W254	A246-V250 WeakPolarHBondContact O-CG2 3.36Å; A246-V250 PolarHBondContact O-N 3.01Å; V247-V250 PolarHBondContact O-N 3.34Å; G248-V250 PolarHBondContact O-N 3.41Å; V250-I252 VanDerWaalsContact C-N 3.31Å; V250-I252 PolarHBondContact O-N 3.47Å; V250-W254 HydrophobicContact CG1-CB 4.06Å; V250-W254 CarbonylContact O-C 3.17Å; V250-W254 WeakPolarHBondContact O-CA 3.24Å; V250-W254 WeakPolarHBondContact O-CB 3.31Å; V250-W254 PolarHBondContact O-N 2.83Å; V250-W254 VanDerWaalsContact O-O 3.04Å
251	C	89.7	Confident	90.9	Very high	4 Å²	4	60.2 Å²	60.2	3%	0.027	30%	0.301	C	S	.	.	H	α-helix	trans	-66	-29.1	-179.3	-68	0	0	0	0	114.1	V247 G248 L260 Q261 Y264	V247-C251 WeakPolarHBondContact O-CB 3.04Å; V247-C251 PolarHBondContact O-N 3.28Å; V247-C251 PolarHBondContact O-SG 3.31Å; G248-C251 PolarHBondContact O-N 2.92Å; C251-L260 WeakPolarHBondContact SG-CD2 3.38Å; C251-Q261 WeakPolarHBondContact O-CG 3.42Å; C251-Y264 HydrophobicContact CB-CD2 3.99Å; C251-Y264 HydrophobicContact CB-CE2 4.45Å
252	I	88.4	Confident	90.6	Very high	4 Å²	4	61.7 Å²	61.7	2%	0.021	31%	0.307	C	S	.	.	H	α-helix	trans	-90.3	-42	-176.9	-64	164.7	0	0	0	112.2	L213 G248 V250 I268 P323 A324	L213-I252 HydrophobicContact CD1-CD1 3.89Å; G248-I252 WeakPolarHBondContact O-CB 3.23Å; G248-I252 WeakPolarHBondContact O-CD1 3.37Å; G248-I252 WeakPolarHBondContact O-CG1 3.38Å; G248-I252 PolarHBondContact O-N 2.69Å; V250-I252 VanDerWaalsContact C-N 3.31Å; V250-I252 PolarHBondContact O-N 3.47Å; I252-I268 HydrophobicContact CD1-CD1 3.26Å; I252-P323 WeakPolarHBondContact O-CB 3.35Å; I252-A324 HydrophobicContact CG2-CB 3.64Å
253	H	86.7	Confident	90.4	Very high	49 Å²	49	56.1 Å²	56.1	23%	0.227	30%	0.295	C	S	.	.	H	α-helix	trans	-105.6	-13.7	-173.5	-62.1	82.3	0	0	0	113.3	I206 S209 M249	I206-H253 VanDerWaalsContact CG1-CD2 3.42Å; I206-H253 WeakPolarHBondContact CG1-CD2 3.19Å; S209-H253 PolarHBondContact OG-CE1 2.91Å; S209-H253 PolarHBondContact OG-NE2 3.28Å; M249-H253 PolarHBondContact O-N 3.36Å
254	W	86	Confident	90.3	Very high	197 Å²	197	53.1 Å²	53.1	75%	0.746	28%	0.278	S	S	*	.	S	Bend	trans	-120.2	-179.7	177.2	-151	-91.9	0	0	0	110.2	V250 G256	V250-W254 HydrophobicContact CG1-CB 4.06Å; V250-W254 CarbonylContact O-C 3.17Å; V250-W254 WeakPolarHBondContact O-CA 3.24Å; V250-W254 WeakPolarHBondContact O-CB 3.31Å; V250-W254 PolarHBondContact O-N 2.83Å; V250-W254 VanDerWaalsContact O-O 3.04Å; W254-G256 PolarHBondContact O-N 3.17Å
255	K	82.6	Confident	90	Very high	178 Å²	178	50.9 Å²	50.9	77%	0.774	27%	0.268	S	S	*	.			trans	-65.7	124.5	171.4	-74.1	-171.9	165.8	77.2	0	110.2
256	G	81.9	Confident	89.9	Confident	12 Å²	12	51.5 Å²	51.5	12%	0.124	27%	0.271	C	S	.	.			trans	-146.8	166.4	173.1	0	0	0	0	0	111.6	W254 W333	W254-G256 PolarHBondContact O-N 3.17Å; G256-W333 WeakPolarHBondContact O-CH2 3.36Å
257	P	89.6	Confident	89.9	Confident	72 Å²	72	52.5 Å²	52.5	47%	0.468	27%	0.271	S	S	.	.			trans	-66.9	134.6	177.1	21.5	-24.7	0	0	0	111.1	V259 L260 Q261	P257-V259 PolarHBondContact O-N 3.11Å; P257-L260 HydrophobicContact CB-CB 4.43Å; P257-L260 HydrophobicContact CG-CB 3.76Å; P257-L260 HydrophobicContact CG-CD2 3.98Å; P257-L260 WeakPolarHBondContact O-CB 3.46Å; P257-L260 PolarHBondContact O-N 2.66Å; P257-Q261 PolarHBondContact O-N 3.5Å
258	L	83.9	Confident	89.8	Confident	34 Å²	34	50.5 Å²	50.5	18%	0.178	26%	0.258	C	S	.	.	H	α-helix	trans	-55	-45.8	-172.8	-69.9	168.1	0	0	0	113.5	L260 Q261 Q262 M331 W333	L258-L260 VanDerWaalsContact C-N 3.26Å; L258-L260 PolarHBondContact O-N 3.32Å; L258-Q261 PolarHBondContact O-N 3.42Å; L258-Q262 WeakPolarHBondContact O-CG 3.47Å; L258-Q262 PolarHBondContact O-N 2.73Å; L258-M331 VanDerWaalsContact CD1-CA 3.5Å; L258-M331 HydrophobicContact CD1-CB 3.97Å; L258-M331 HydrophobicContact CD1-CG 4.18Å; L258-W333 HydrophobicContact CD1-CG 4.46Å; L258-W333 VanDerWaalsContact CD1-NE1 3.35Å; L258-W333 HydrophobicContact CG-CZ2 4.41Å
259	V	89.1	Confident	89.8	Confident	114 Å²	114	50.5 Å²	50.5	69%	0.691	26%	0.259	S	S	*	.	H	α-helix	trans	-61	-38.9	179.5	178.9	0	0	0	0	111	P257 Q262 A263	P257-V259 PolarHBondContact O-N 3.11Å; V259-Q262 PolarHBondContact O-N 3.05Å; V259-A263 WeakPolarHBondContact O-CB 3.12Å; V259-A263 PolarHBondContact O-N 2.79Å
260	L	90.7	Very high	90	Very high	65 Å²	65	49.3 Å²	49.3	34%	0.34	25%	0.253	S	S	.	.	H	α-helix	trans	-71.3	-41.2	178.5	-169.9	59.3	0	0	0	111.1	V247 C251 P257 L258 Q262 A263 Y264	V247-L260 HydrophobicContact CG1-CD2 4.04Å; C251-L260 WeakPolarHBondContact SG-CD2 3.38Å; P257-L260 HydrophobicContact CB-CB 4.43Å; P257-L260 HydrophobicContact CG-CB 3.76Å; P257-L260 HydrophobicContact CG-CD2 3.98Å; P257-L260 WeakPolarHBondContact O-CB 3.46Å; P257-L260 PolarHBondContact O-N 2.66Å; L258-L260 VanDerWaalsContact C-N 3.26Å; L258-L260 PolarHBondContact O-N 3.32Å; L260-Q262 VanDerWaalsContact C-N 3.34Å; L260-Q262 PolarHBondContact O-N 3.44Å; L260-A263 PolarHBondContact O-N 2.96Å; L260-Y264 HydrophobicContact CD1-CD2 4.12Å; L260-Y264 HydrophobicContact CD1-CE2 3.72Å; L260-Y264 HydrophobicContact CD2-CE2 4.33Å; L260-Y264 HydrophobicContact CG-CD2 3.95Å; L260-Y264 HydrophobicContact CG-CE2 3.75Å; L260-Y264 VanDerWaalsContact O-CD2 3.23Å; L260-Y264 WeakPolarHBondContact O-CD2 3.36Å; L260-Y264 PolarHBondContact O-N 3.34Å
261	Q	90.3	Very high	90.1	Very high	39 Å²	39	45.9 Å²	45.9	18%	0.182	23%	0.232	C	C	.	.	H	α-helix	trans	-58.4	-46.1	172.5	-177.4	-179.7	-17.6	0	0	111	C251 P257 L258 A263 Y264 L265	C251-Q261 WeakPolarHBondContact O-CG 3.42Å; P257-Q261 PolarHBondContact O-N 3.5Å; L258-Q261 PolarHBondContact O-N 3.42Å; Q261-A263 PolarHBondContact O-N 2.82Å; Q261-Y264 PolarHBondContact O-N 3.13Å; Q261-L265 HydrophobicContact CG-CD1 4.27Å; Q261-L265 VanDerWaalsContact O-CG 3.28Å; Q261-L265 WeakPolarHBondContact O-CG 3.3Å; Q261-L265 PolarHBondContact O-N 3.37Å
262	Q	90.8	Very high	90.3	Very high	40 Å²	40	47.9 Å²	47.9	19%	0.187	24%	0.241	C	C	.	.	H	α-helix	trans	-59.8	-44.3	175.4	-72	175.8	-14.2	0	0	111.8	L258 V259 L260 Y264 L265 I266 Y327 S328	L258-Q262 WeakPolarHBondContact O-CG 3.47Å; L258-Q262 PolarHBondContact O-N 2.73Å; V259-Q262 PolarHBondContact O-N 3.05Å; L260-Q262 VanDerWaalsContact C-N 3.34Å; L260-Q262 PolarHBondContact O-N 3.44Å; Q262-Y264 PolarHBondContact O-N 2.92Å; Q262-L265 PolarHBondContact O-N 3.24Å; Q262-I266 VanDerWaalsContact O-CG1 3.27Å; Q262-I266 WeakPolarHBondContact O-CG1 3.44Å; Q262-I266 PolarHBondContact O-N 3.35Å; Q262-Y327 HydrophobicContact CB-CE2 3.8Å; Q262-Y327 VanDerWaalsContact CD-OH 3.27Å; Q262-Y327 HydrophobicContact CG-CE2 3.64Å; Q262-S328 PolarHBondContact NE2-O 3.2Å
263	A	92.6	Very high	90.6	Very high	44 Å²	44	47.7 Å²	47.7	36%	0.364	24%	0.24	S	C	.	.	H	α-helix	trans	-60.3	-44	175.7	0	0	0	0	0	112.2	V259 L260 Q261 I266 M267	V259-A263 WeakPolarHBondContact O-CB 3.12Å; V259-A263 PolarHBondContact O-N 2.79Å; L260-A263 PolarHBondContact O-N 2.96Å; Q261-A263 PolarHBondContact O-N 2.82Å; A263-I266 PolarHBondContact O-N 3.28Å; A263-M267 WeakPolarHBondContact O-CG 3.49Å; A263-M267 PolarHBondContact O-N 2.93Å
264	Y	93.6	Very high	90.9	Very high	22 Å²	22	45.5 Å²	45.5	9%	0.086	23%	0.23	C	C	.	.	H	α-helix	trans	-65	-39.1	175.2	-84.8	-71.9	0	0	0	112.6	L213 F244 V247 G248 C251 L260 Q261 Q262 I266 M267 I268	L213-Y264 HydrophobicContact CD2-CD1 4.24Å; F244-Y264 HydrophobicContact CD1-CE1 4.39Å; F244-Y264 AromaticContact CD2-CE1 3.79Å; F244-Y264 HydrophobicContact CD2-CE1 3.79Å; F244-Y264 HydrophobicContact CE1-CE1 4.2Å; F244-Y264 HydrophobicContact CE2-CD1 4.17Å; F244-Y264 AromaticContact CE2-CE1 3.55Å; F244-Y264 HydrophobicContact CE2-CE1 3.55Å; F244-Y264 HydrophobicContact CG-CE1 4.22Å; F244-Y264 HydrophobicContact CZ-CD1 4.06Å; F244-Y264 AromaticContact CZ-CE1 3.78Å; F244-Y264 HydrophobicContact CZ-CE1 3.78Å; F244-Y264 WeakPolarHBondContact O-CE1 3.49Å; F244-Y264 PolarHBondContact O-OH 3.32Å; V247-Y264 HydrophobicContact CB-CE2 4.5Å; V247-Y264 WeakPolarHBondContact CB-OH 3.37Å; V247-Y264 HydrophobicContact CG1-CE2 3.8Å; V247-Y264 WeakPolarHBondContact CG1-OH 3.28Å; G248-Y264 VanDerWaalsContact CA-CD1 3.5Å; C251-Y264 HydrophobicContact CB-CD2 3.99Å; C251-Y264 HydrophobicContact CB-CE2 4.45Å; L260-Y264 HydrophobicContact CD1-CD2 4.12Å; L260-Y264 HydrophobicContact CD1-CE2 3.72Å; L260-Y264 HydrophobicContact CD2-CE2 4.33Å; L260-Y264 HydrophobicContact CG-CD2 3.95Å; L260-Y264 HydrophobicContact CG-CE2 3.75Å; L260-Y264 VanDerWaalsContact O-CD2 3.23Å; L260-Y264 WeakPolarHBondContact O-CD2 3.36Å; L260-Y264 PolarHBondContact O-N 3.34Å; Q261-Y264 PolarHBondContact O-N 3.13Å; Q262-Y264 PolarHBondContact O-N 2.92Å; Y264-I266 VanDerWaalsContact C-N 3.35Å; Y264-M267 PolarHBondContact O-N 3.43Å; Y264-I268 WeakPolarHBondContact O-CB 3.35Å; Y264-I268 VanDerWaalsContact O-CG1 3.31Å; Y264-I268 WeakPolarHBondContact O-CG1 3.26Å; Y264-I268 PolarHBondContact O-N 3.08Å
265	L	91.4	Very high	91.2	Very high	3 Å²	3	37.3 Å²	37.3	2%	0.016	20%	0.202	C	C	.	.	H	α-helix	trans	-62.8	-41.6	175.7	-71.7	175.1	0	0	0	111.7	Q261 Q262 I268 S269 Y327 L397	Q261-L265 HydrophobicContact CG-CD1 4.27Å; Q261-L265 VanDerWaalsContact O-CG 3.28Å; Q261-L265 WeakPolarHBondContact O-CG 3.3Å; Q261-L265 PolarHBondContact O-N 3.37Å; Q262-L265 PolarHBondContact O-N 3.24Å; L265-I268 PolarHBondContact O-N 3.46Å; L265-S269 PolarHBondContact O-N 2.8Å; L265-S269 PolarHBondContact O-OG 2.75Å; L265-S269 VanDerWaalsContact O-OG 3.11Å; L265-Y327 HydrophobicContact CB-CD2 4.33Å; L265-Y327 HydrophobicContact CD1-CD2 4.12Å; L265-L397 HydrophobicContact CB-CD2 3.96Å; L265-L397 HydrophobicContact CD1-CD2 4.49Å; L265-L397 HydrophobicContact CD2-CD1 3.72Å; L265-L397 HydrophobicContact CD2-CD2 4Å; L265-L397 HydrophobicContact CD2-CG 4.48Å; L265-L397 HydrophobicContact CG-CD2 4.37Å
266	I	93.6	Very high	91.7	Very high	12 Å²	12	30.9 Å²	30.9	6%	0.062	17%	0.174	C	C	.	.	H	α-helix	trans	-64.3	-41.3	174.2	-64.7	161.6	0	0	0	111.2	P127 L130 C131 Q262 A263 Y264 S269 A270	P127-I266 HydrophobicContact CB-CD1 3.65Å; P127-I266 HydrophobicContact CB-CG1 4.06Å; L130-I266 HydrophobicContact CD2-CG2 3.69Å; C131-I266 HydrophobicContact CB-CG2 3.76Å; Q262-I266 VanDerWaalsContact O-CG1 3.27Å; Q262-I266 WeakPolarHBondContact O-CG1 3.44Å; Q262-I266 PolarHBondContact O-N 3.35Å; A263-I266 PolarHBondContact O-N 3.28Å; Y264-I266 VanDerWaalsContact C-N 3.35Å; I266-S269 WeakPolarHBondContact CA-OG 3.01Å; I266-S269 PolarHBondContact O-N 3.08Å; I266-S269 PolarHBondContact O-OG 3.43Å; I266-A270 WeakPolarHBondContact O-CB 3.12Å; I266-A270 PolarHBondContact O-N 3.3Å
267	M	94.1	Very high	92.1	Very high	51 Å²	51	30.5 Å²	30.5	25%	0.251	17%	0.169	S	C	.	.	H	α-helix	trans	-66.4	-39.3	176.5	-73.7	-59.4	-62.4	0	0	112.3	V134 F244 A263 Y264 A270 L271	V134-M267 HydrophobicContact CG1-SD 4.43Å; F244-M267 HydrophobicContact CZ-CB 4.31Å; A263-M267 WeakPolarHBondContact O-CG 3.49Å; A263-M267 PolarHBondContact O-N 2.93Å; Y264-M267 PolarHBondContact O-N 3.43Å; M267-A270 PolarHBondContact O-N 2.9Å; M267-L271 WeakPolarHBondContact O-CB 3.21Å; M267-L271 VanDerWaalsContact O-CG 3.31Å; M267-L271 WeakPolarHBondContact O-CG 3.47Å; M267-L271 PolarHBondContact O-N 3.46Å
268	I	93.3	Very high	92.2	Very high	18 Å²	18	28.1 Å²	28.1	9%	0.092	15%	0.152	C	C	.	.	H	α-helix	trans	-64.3	-45	176.2	-75.9	-178.8	0	0	0	111.1	L212 L213 I252 Y264 L265 A270 L271 M272	L212-I268 HydrophobicContact CD1-CG2 3.78Å; L212-I268 HydrophobicContact CD2-CB 4.25Å; L212-I268 HydrophobicContact CD2-CG1 3.94Å; L212-I268 HydrophobicContact CD2-CG2 3.98Å; L213-I268 HydrophobicContact CD1-CD1 4.19Å; L213-I268 HydrophobicContact CD2-CD1 3.86Å; L213-I268 HydrophobicContact CD2-CG1 3.66Å; L213-I268 HydrophobicContact CG-CD1 3.9Å; L213-I268 HydrophobicContact CG-CG1 4.15Å; I252-I268 HydrophobicContact CD1-CD1 3.26Å; Y264-I268 WeakPolarHBondContact O-CB 3.35Å; Y264-I268 VanDerWaalsContact O-CG1 3.31Å; Y264-I268 WeakPolarHBondContact O-CG1 3.26Å; Y264-I268 PolarHBondContact O-N 3.08Å; L265-I268 PolarHBondContact O-N 3.46Å; I268-A270 VanDerWaalsContact C-N 3.34Å; I268-L271 PolarHBondContact O-N 3.22Å; I268-M272 WeakPolarHBondContact O-CB 3.22Å; I268-M272 WeakPolarHBondContact O-CG 3.2Å; I268-M272 PolarHBondContact O-N 3.22Å
269	S	94.1	Very high	92.4	Very high	1 Å²	1	30.7 Å²	30.7	1%	0.007	16%	0.159	C	C	.	.	H	α-helix	trans	-64.8	-39.7	177.5	54.1	0	0	0	0	111.4	C131 L265 I266 M272 A273	C131-S269 PolarHBondContact SG-OG 3.28Å; L265-S269 PolarHBondContact O-N 2.8Å; L265-S269 PolarHBondContact O-OG 2.75Å; L265-S269 VanDerWaalsContact O-OG 3.11Å; I266-S269 WeakPolarHBondContact CA-OG 3.01Å; I266-S269 PolarHBondContact O-N 3.08Å; I266-S269 PolarHBondContact O-OG 3.43Å; S269-M272 PolarHBondContact O-N 3.36Å; S269-A273 WeakPolarHBondContact O-CB 3.49Å; S269-A273 PolarHBondContact O-N 3.31Å
270	A	95.8	Very high	92.2	Very high	1 Å²	1	25.7 Å²	25.7	1%	0.008	13%	0.129	C	C	.	.	H	α-helix	trans	-62.1	-48.3	173.9	0	0	0	0	0	112.4	V134 V135 I266 M267 I268 M272 A273 L274	V134-A270 HydrophobicContact CB-CB 4.46Å; V134-A270 HydrophobicContact CG1-CB 3.91Å; V135-A270 HydrophobicContact CG2-CB 3.64Å; I266-A270 WeakPolarHBondContact O-CB 3.12Å; I266-A270 PolarHBondContact O-N 3.3Å; M267-A270 PolarHBondContact O-N 2.9Å; I268-A270 VanDerWaalsContact C-N 3.34Å; A270-M272 VanDerWaalsContact C-N 3.34Å; A270-M272 PolarHBondContact O-N 3.48Å; A270-A273 PolarHBondContact O-N 3.41Å; A270-L274 VanDerWaalsContact O-CG 3.31Å; A270-L274 WeakPolarHBondContact O-CG 3.05Å; A270-L274 PolarHBondContact O-N 2.97Å
271	L	94.5	Very high	92	Very high	4 Å²	4	24.2 Å²	24.2	2%	0.021	12%	0.123	C	C	.	.	H	α-helix	trans	-60.6	-42.1	176.8	-74.4	170.6	0	0	0	111.6	L212 Y220 M267 I268 L274 V275	L212-L271 HydrophobicContact CD2-CB 4.31Å; L212-L271 HydrophobicContact CD2-CD1 4.34Å; Y220-L271 HydrophobicContact CD2-CD2 4.24Å; Y220-L271 HydrophobicContact CG-CD2 3.98Å; M267-L271 WeakPolarHBondContact O-CB 3.21Å; M267-L271 VanDerWaalsContact O-CG 3.31Å; M267-L271 WeakPolarHBondContact O-CG 3.47Å; M267-L271 PolarHBondContact O-N 3.46Å; I268-L271 PolarHBondContact O-N 3.22Å; L271-L274 PolarHBondContact O-N 2.84Å; L271-V275 VanDerWaalsContact O-CG2 3.27Å; L271-V275 WeakPolarHBondContact O-CG2 3.16Å; L271-V275 PolarHBondContact O-N 2.86Å
272	M	93.4	Very high	91.8	Very high	46 Å²	46	25 Å²	25	23%	0.227	13%	0.127	C	C	.	.	H	α-helix	trans	-64.7	-39.8	175.4	-76.4	-59.9	-61.7	0	0	112.7	L212 I268 S269 A270 V275 F276 I401	L212-M272 HydrophobicContact CD1-CG 3.55Å; L212-M272 HydrophobicContact CD1-SD 3.45Å; L212-M272 WeakPolarHBondContact CD1-SD 3.46Å; L212-M272 HydrophobicContact CG-CG 4.27Å; L212-M272 HydrophobicContact CG-SD 3.96Å; I268-M272 WeakPolarHBondContact O-CB 3.22Å; I268-M272 WeakPolarHBondContact O-CG 3.2Å; I268-M272 PolarHBondContact O-N 3.22Å; S269-M272 PolarHBondContact O-N 3.36Å; A270-M272 VanDerWaalsContact C-N 3.34Å; A270-M272 PolarHBondContact O-N 3.48Å; M272-V275 WeakPolarHBondContact O-CB 2.96Å; M272-V275 PolarHBondContact O-N 2.79Å; M272-F276 HydrophobicContact CE-CE2 4.26Å; M272-F276 VanDerWaalsContact O-CD2 3.27Å; M272-F276 WeakPolarHBondContact O-CD2 3.22Å; M272-F276 PolarHBondContact O-N 3.25Å; M272-I401 HydrophobicContact CB-CD1 3.9Å; M272-I401 HydrophobicContact CB-CG1 4.02Å; M272-I401 HydrophobicContact CB-CG2 4.25Å; M272-I401 HydrophobicContact CG-CD1 4.35Å
273	A	95.3	Very high	91.7	Very high	0 Å²	0	27.2 Å²	27.2	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-63.5	-43.2	175	0	0	0	0	0	111.5	V135 S269 A270 V275 F276 I277 I401 S404 V405	V135-A273 HydrophobicContact CG2-CB 4.12Å; S269-A273 WeakPolarHBondContact O-CB 3.49Å; S269-A273 PolarHBondContact O-N 3.31Å; A270-A273 PolarHBondContact O-N 3.41Å; A273-V275 VanDerWaalsContact C-N 3.33Å; A273-V275 PolarHBondContact O-N 3.24Å; A273-F276 WeakPolarHBondContact O-CB 3.26Å; A273-F276 PolarHBondContact O-N 3Å; A273-F276 VanDerWaalsContact O-N 3.17Å; A273-I277 WeakPolarHBondContact O-CD1 3.42Å; A273-I277 VanDerWaalsContact O-CG1 3.26Å; A273-I277 WeakPolarHBondContact O-CG1 3.47Å; A273-I277 PolarHBondContact O-N 3.5Å; A273-I401 HydrophobicContact CB-CG2 4.43Å; A273-S404 VanDerWaalsContact CB-CB 3.5Å; A273-V405 HydrophobicContact CB-CG2 3.84Å
274	L	93.9	Very high	91.6	Very high	2 Å²	2	25.2 Å²	25.2	1%	0.01	12%	0.117	C	C	.	.	H	α-helix	trans	-61.9	-39.3	175.5	-71.2	170.2	0	0	0	112.4	V135 T138 I139 Y145 Y220 A270 L271 I277 K278	V135-L274 HydrophobicContact CG1-CD2 4.22Å; V135-L274 HydrophobicContact CG2-CG 4.48Å; T138-L274 HydrophobicContact CG2-CD1 3.73Å; T138-L274 HydrophobicContact CG2-CD2 3.7Å; T138-L274 HydrophobicContact CG2-CG 4.39Å; I139-L274 HydrophobicContact CD1-CD2 3.69Å; I139-L274 HydrophobicContact CG1-CD2 4.05Å; Y145-L274 HydrophobicContact CD1-CB 3.98Å; Y145-L274 HydrophobicContact CD1-CD2 4.22Å; Y145-L274 HydrophobicContact CD2-CD2 4.39Å; Y145-L274 HydrophobicContact CE1-CB 3.66Å; Y145-L274 HydrophobicContact CE1-CD2 4.45Å; Y145-L274 HydrophobicContact CE1-CG 4.45Å; Y145-L274 HydrophobicContact CG-CD2 4.2Å; Y220-L274 HydrophobicContact CD2-CD1 4.15Å; Y220-L274 HydrophobicContact CE2-CD1 4.14Å; A270-L274 VanDerWaalsContact O-CG 3.31Å; A270-L274 WeakPolarHBondContact O-CG 3.05Å; A270-L274 PolarHBondContact O-N 2.97Å; L271-L274 PolarHBondContact O-N 2.84Å; L274-I277 PolarHBondContact O-N 3.35Å; L274-K278 WeakPolarHBondContact O-CB 3.4Å; L274-K278 PolarHBondContact O-N 2.98Å
275	V	92.1	Very high	91.5	Very high	25 Å²	25	24.1 Å²	24.1	15%	0.152	11%	0.112	C	C	.	.	H	α-helix	trans	-58.5	-51.5	171.4	167	0	0	0	0	109.7	F216 L271 M272 A273 I277 K278 Y279	F216-V275 HydrophobicContact CD1-CG2 3.47Å; F216-V275 VanDerWaalsContact CD1-CG2 3.47Å; F216-V275 HydrophobicContact CD2-CG2 4.22Å; F216-V275 HydrophobicContact CE1-CG1 4.33Å; F216-V275 HydrophobicContact CE1-CG2 3.4Å; F216-V275 HydrophobicContact CE2-CG2 4.19Å; F216-V275 HydrophobicContact CG-CG2 3.91Å; F216-V275 HydrophobicContact CZ-CG1 4.23Å; F216-V275 HydrophobicContact CZ-CG2 3.79Å; L271-V275 VanDerWaalsContact O-CG2 3.27Å; L271-V275 WeakPolarHBondContact O-CG2 3.16Å; L271-V275 PolarHBondContact O-N 2.86Å; M272-V275 WeakPolarHBondContact O-CB 2.96Å; M272-V275 PolarHBondContact O-N 2.79Å; A273-V275 VanDerWaalsContact C-N 3.33Å; A273-V275 PolarHBondContact O-N 3.24Å; V275-I277 VanDerWaalsContact C-N 3.32Å; V275-I277 PolarHBondContact O-N 3.01Å; V275-K278 PolarHBondContact O-N 3.4Å; V275-Y279 HydrophobicContact CB-CD2 4.33Å; V275-Y279 HydrophobicContact CG1-CD2 3.58Å; V275-Y279 HydrophobicContact CG1-CE2 3.91Å; V275-Y279 VanDerWaalsContact O-CB 3.25Å; V275-Y279 WeakPolarHBondContact O-CB 3.43Å; V275-Y279 WeakPolarHBondContact O-CD2 3.11Å; V275-Y279 PolarHBondContact O-N 3.39Å
276	F	91.8	Very high	91.5	Very high	43 Å²	43	25.1 Å²	25.1	19%	0.189	12%	0.116	C	C	.	.	H	α-helix	trans	-59.1	-40.7	176	-82.5	-61.1	0	0	0	112.9	M272 A273 Y279 L280 I401 V405	M272-F276 HydrophobicContact CE-CE2 4.26Å; M272-F276 VanDerWaalsContact O-CD2 3.27Å; M272-F276 WeakPolarHBondContact O-CD2 3.22Å; M272-F276 PolarHBondContact O-N 3.25Å; A273-F276 WeakPolarHBondContact O-CB 3.26Å; A273-F276 PolarHBondContact O-N 3Å; A273-F276 VanDerWaalsContact O-N 3.17Å; F276-Y279 PolarHBondContact O-N 2.91Å; F276-L280 HydrophobicContact CB-CD1 4.12Å; F276-L280 HydrophobicContact CD1-CD1 3.76Å; F276-L280 HydrophobicContact CD1-CG 4.22Å; F276-L280 HydrophobicContact CG-CD1 4.36Å; F276-L280 WeakPolarHBondContact O-CB 3.43Å; F276-L280 VanDerWaalsContact O-CG 3.22Å; F276-L280 WeakPolarHBondContact O-CG 3.48Å; F276-L280 PolarHBondContact O-N 3.39Å; F276-I401 HydrophobicContact CD2-CG2 3.73Å; F276-I401 HydrophobicContact CE2-CG2 3.87Å; F276-V405 HydrophobicContact CB-CG1 4.47Å; F276-V405 HydrophobicContact CB-CG2 3.59Å; F276-V405 HydrophobicContact CD2-CG2 4.18Å; F276-V405 HydrophobicContact CG-CG2 4.22Å
277	I	91.8	Very high	91.5	Very high	5 Å²	5	26.3 Å²	26.3	3%	0.026	12%	0.124	C	C	.	.	H	α-helix	trans	-64.5	-43.4	179.1	-67.4	159.5	0	0	0	111.2	V135 I139 A273 L274 V275 Y279 K409	V135-I277 HydrophobicContact CG1-CD1 3.69Å; I139-I277 HydrophobicContact CD1-CB 4.27Å; I139-I277 HydrophobicContact CD1-CD1 4.01Å; I139-I277 HydrophobicContact CD1-CG2 3.59Å; I139-I277 HydrophobicContact CG1-CD1 4.12Å; A273-I277 WeakPolarHBondContact O-CD1 3.42Å; A273-I277 VanDerWaalsContact O-CG1 3.26Å; A273-I277 WeakPolarHBondContact O-CG1 3.47Å; A273-I277 PolarHBondContact O-N 3.5Å; L274-I277 PolarHBondContact O-N 3.35Å; V275-I277 VanDerWaalsContact C-N 3.32Å; V275-I277 PolarHBondContact O-N 3.01Å; I277-Y279 VanDerWaalsContact C-N 3.35Å; I277-Y279 PolarHBondContact O-N 2.94Å; I277-K409 HydrophobicContact CG1-CD 4.35Å; I277-K409 HydrophobicContact CG1-CG 4.27Å; I277-K409 HydrophobicContact CG2-CD 4.14Å; I277-K409 PolarHBondContact O-NZ 3.04Å
278	K	90.4	Very high	91.4	Very high	22 Å²	22	24 Å²	24	10%	0.096	11%	0.113	C	C	.	.	H	α-helix	trans	-64.6	-39.4	178.5	-176	70.6	-175.4	102.6	0	112.7	F144 Y145 E147 N149 L274 V275	F144-K278 HydrophobicContact CD1-CD 3.94Å; F144-K278 HydrophobicContact CE1-CD 3.72Å; F144-K278 VanDerWaalsContact CE1-CE 3.44Å; F144-K278 HydrophobicContact CE1-CG 4.23Å; F144-K278 HydrophobicContact CZ-CD 4.25Å; F144-K278 VanDerWaalsContact CZ-CE 3.46Å; F144-K278 WeakPolarHBondContact O-CD 3.4Å; F144-K278 WeakPolarHBondContact O-CE 3.32Å; F144-K278 PolarHBondContact O-NZ 2.81Å; Y145-K278 HydrophobicContact CD1-CB 4.07Å; Y145-K278 HydrophobicContact CD1-CD 4.43Å; E147-K278 PolarHBondContact O-NZ 3.33Å; N149-K278 PolarHBondContact ND2-NZ 2.96Å; L274-K278 WeakPolarHBondContact O-CB 3.4Å; L274-K278 PolarHBondContact O-N 2.98Å; V275-K278 PolarHBondContact O-N 3.4Å
279	Y	87.9	Confident	91.4	Very high	87 Å²	87	23.3 Å²	23.3	34%	0.341	11%	0.109	S	C	.	.	H	α-helix	trans	-102.8	-6.8	-164.7	-75.7	-49.7	0	0	0	114.2	L152 Y154 V275 F276 I277	L152-Y279 HydrophobicContact CD1-CD1 4.37Å; L152-Y279 WeakPolarHBondContact CD1-O 3.42Å; L152-Y279 HydrophobicContact CD2-CD1 3.83Å; L152-Y279 HydrophobicContact CD2-CE1 4.31Å; Y154-Y279 WeakPolarHBondContact CE2-O 3.35Å; Y154-Y279 WeakPolarHBondContact OH-CB 3.38Å; Y154-Y279 WeakPolarHBondContact OH-CD1 3.38Å; Y154-Y279 VanDerWaalsContact OH-CG 3.28Å; Y154-Y279 PolarHBondContact OH-O 3.03Å; V275-Y279 HydrophobicContact CB-CD2 4.33Å; V275-Y279 HydrophobicContact CG1-CD2 3.58Å; V275-Y279 HydrophobicContact CG1-CE2 3.91Å; V275-Y279 VanDerWaalsContact O-CB 3.25Å; V275-Y279 WeakPolarHBondContact O-CB 3.43Å; V275-Y279 WeakPolarHBondContact O-CD2 3.11Å; V275-Y279 PolarHBondContact O-N 3.39Å; F276-Y279 PolarHBondContact O-N 2.91Å; I277-Y279 VanDerWaalsContact C-N 3.35Å; I277-Y279 PolarHBondContact O-N 2.94Å
280	L	85.4	Confident	91.3	Very high	10 Å²	10	24.3 Å²	24.3	5%	0.052	12%	0.119	C	C	.	.	S	Bend	trans	-101.9	129.2	175.2	-67.6	176.2	0	0	0	111.3	M178 F276 A285 I288 K409	M178-L280 HydrophobicContact CE-CD2 3.85Å; F276-L280 HydrophobicContact CB-CD1 4.12Å; F276-L280 HydrophobicContact CD1-CD1 3.76Å; F276-L280 HydrophobicContact CD1-CG 4.22Å; F276-L280 HydrophobicContact CG-CD1 4.36Å; F276-L280 WeakPolarHBondContact O-CB 3.43Å; F276-L280 VanDerWaalsContact O-CG 3.22Å; F276-L280 WeakPolarHBondContact O-CG 3.48Å; F276-L280 PolarHBondContact O-N 3.39Å; L280-A285 HydrophobicContact CB-CB 3.95Å; L280-A285 HydrophobicContact CD1-CB 4.28Å; L280-I288 HydrophobicContact CD1-CD1 4.34Å; L280-I288 HydrophobicContact CD1-CG2 4.34Å; L280-I288 HydrophobicContact CD2-CD1 3.73Å; L280-K409 PolarHBondContact O-NZ 2.9Å
281	P	87	Confident	91.2	Very high	33 Å²	33	25.9 Å²	25.9	21%	0.214	13%	0.132	C	C	.	.			trans	-56.1	159.4	164.4	-23.6	34.3	0	0	0	112.1	T155 E159 A285	T155-P281 HydrophobicContact CG2-CG 3.97Å; E159-P281 VanDerWaalsContact CD-CB 3.43Å; E159-P281 HydrophobicContact CG-CB 4.3Å; E159-P281 WeakPolarHBondContact OE1-CB 3.34Å; E159-P281 WeakPolarHBondContact OE2-CB 3.45Å; P281-A285 VanDerWaalsContact O-CB 3.22Å; P281-A285 WeakPolarHBondContact O-CB 3.33Å; P281-A285 PolarHBondContact O-N 3.38Å
282	E	85	Confident	91	Very high	56 Å²	56	26.4 Å²	26.4	26%	0.262	14%	0.135	S	C	.	.	H	α-helix	trans	-62.6	-53.1	-173.3	-72.3	169.6	-178.8	0	0	112.7	K148 R167 A285 W286	K148-E282 WeakPolarHBondContact CE-OE1 3.29Å; K148-E282 IonicContact NZ-OE1 3.75Å; K148-E282 PolarHBondContact NZ-OE1 2.84Å; K148-E282 IonicContact NZ-OE2 3.37Å; K148-E282 PolarHBondContact NZ-OE2 3.48Å; R167-E282 IonicContact NH2-OE2 2.7Å; E282-A285 PolarHBondContact O-N 3.26Å; E282-W286 PolarHBondContact O-N 3.02Å; E282-W286 PolarHBondContact O-NE1 3.41Å
283	W	88.4	Confident	90.8	Very high	87 Å²	87	24.5 Å²	24.5	33%	0.33	13%	0.126	S	C	.	.	H	α-helix	trans	-71.4	-43.8	-177.4	-75	70.1	0	0	0	111.3	E159 R167 L168 A285 W286 V287	E159-W283 WeakPolarHBondContact OE2-CB 3.5Å; E159-W283 PolarHBondContact OE2-N 2.97Å; R167-W283 HydrophobicContact CG-CG 4.32Å; R167-W283 VanDerWaalsContact NE-NE1 3.12Å; L168-W283 HydrophobicContact CD1-CE3 4.3Å; L168-W283 HydrophobicContact CD1-CZ3 4.41Å; W283-A285 PolarHBondContact O-N 2.96Å; W283-W286 PolarHBondContact O-N 2.99Å; W283-W286 VanDerWaalsContact O-N 3.14Å; W283-V287 WeakPolarHBondContact O-CG2 3.49Å; W283-V287 PolarHBondContact O-N 3.26Å
284	S	90.9	Very high	90.6	Very high	1 Å²	1	28.7 Å²	28.7	1%	0.007	15%	0.152	C	C	.	.	H	α-helix	trans	-56.3	-36.1	177	-63.2	0	0	0	0	111.5	E159 T175 I288	E159-S284 VanDerWaalsContact OE1-CB 3.26Å; E159-S284 WeakPolarHBondContact OE1-CB 3.4Å; E159-S284 PolarHBondContact OE1-N 3.36Å; E159-S284 PolarHBondContact OE1-OG 3.36Å; T175-S284 PolarHBondContact OG1-O 3.36Å; T175-S284 VanDerWaalsContact OG1-O 3.12Å; S284-I288 VanDerWaalsContact O-CB 3.22Å; S284-I288 WeakPolarHBondContact O-CB 3.28Å; S284-I288 PolarHBondContact O-N 2.89Å
285	A	90.8	Very high	90.3	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-64.2	-48	176.8	0	0	0	0	0	112.5	L280 P281 E282 W283 V287 I288 L289 K409	L280-A285 HydrophobicContact CB-CB 3.95Å; L280-A285 HydrophobicContact CD1-CB 4.28Å; P281-A285 VanDerWaalsContact O-CB 3.22Å; P281-A285 WeakPolarHBondContact O-CB 3.33Å; P281-A285 PolarHBondContact O-N 3.38Å; E282-A285 PolarHBondContact O-N 3.26Å; W283-A285 PolarHBondContact O-N 2.96Å; A285-V287 VanDerWaalsContact C-N 3.35Å; A285-V287 PolarHBondContact O-N 3.22Å; A285-I288 PolarHBondContact O-N 3.1Å; A285-L289 WeakPolarHBondContact O-CG 3.35Å; A285-L289 PolarHBondContact O-N 3.36Å; A285-K409 HydrophobicContact CB-CD 4.35Å; A285-K409 HydrophobicContact CB-CG 4.34Å
286	W	92.4	Very high	90	Very high	23 Å²	23	31.5 Å²	31.5	9%	0.087	16%	0.162	C	C	.	.	H	α-helix	trans	-63	-42.4	177.7	-61.3	118.1	0	0	0	111.7	E282 W283 L289 G290 L406 K409 L457 Y460 F461	E282-W286 PolarHBondContact O-N 3.02Å; E282-W286 PolarHBondContact O-NE1 3.41Å; W283-W286 PolarHBondContact O-N 2.99Å; W283-W286 VanDerWaalsContact O-N 3.14Å; W286-L289 HydrophobicContact CE3-CD1 4.12Å; W286-L289 HydrophobicContact CZ3-CD1 4.3Å; W286-L289 PolarHBondContact O-N 3.32Å; W286-G290 PolarHBondContact O-N 3.29Å; W286-G290 VanDerWaalsContact O-N 3.13Å; W286-L406 HydrophobicContact CZ3-CG 4.28Å; W286-K409 HydrophobicContact CH2-CB 3.96Å; W286-K409 HydrophobicContact CZ2-CB 3.94Å; W286-L457 HydrophobicContact CE3-CD2 3.44Å; W286-L457 VanDerWaalsContact CE3-CD2 3.44Å; W286-L457 HydrophobicContact CZ3-CD2 3.9Å; W286-Y460 HydrophobicContact CD2-CD1 4.41Å; W286-Y460 HydrophobicContact CD2-CE1 4.21Å; W286-Y460 AromaticContact CE2-CE1 3.59Å; W286-Y460 AromaticContact CE2-CZ 3.78Å; W286-Y460 HydrophobicContact CE3-CD1 4.27Å; W286-Y460 HydrophobicContact CE3-CE1 4.49Å; W286-Y460 AromaticContact CH2-CD1 3.67Å; W286-Y460 HydrophobicContact CH2-CD1 3.67Å; W286-Y460 AromaticContact CH2-CD2 3.46Å; W286-Y460 HydrophobicContact CH2-CD2 3.46Å; W286-Y460 VanDerWaalsContact CH2-CD2 3.46Å; W286-Y460 AromaticContact CH2-CE1 3.67Å; W286-Y460 HydrophobicContact CH2-CE1 3.67Å; W286-Y460 AromaticContact CH2-CE2 3.46Å; W286-Y460 HydrophobicContact CH2-CE2 3.46Å; W286-Y460 VanDerWaalsContact CH2-CE2 3.46Å; W286-Y460 AromaticContact CH2-CG 3.57Å; W286-Y460 HydrophobicContact CH2-CG 3.57Å; W286-Y460 AromaticContact CH2-CZ 3.56Å; W286-Y460 AromaticContact CZ2-CD1 3.85Å; W286-Y460 HydrophobicContact CZ2-CD1 3.85Å; W286-Y460 AromaticContact CZ2-CD2 3.97Å; W286-Y460 HydrophobicContact CZ2-CD2 3.97Å; W286-Y460 AromaticContact CZ2-CE1 3.33Å; W286-Y460 HydrophobicContact CZ2-CE1 3.33Å; W286-Y460 AromaticContact CZ2-CE2 3.47Å; W286-Y460 HydrophobicContact CZ2-CE2 3.47Å; W286-Y460 VanDerWaalsContact CZ2-CE2 3.47Å; W286-Y460 HydrophobicContact CZ2-CG 4.14Å; W286-Y460 AromaticContact CZ2-CZ 3.11Å; W286-Y460 WeakPolarHBondContact CZ2-OH 3.14Å; W286-Y460 AromaticContact CZ3-CD1 3.88Å; W286-Y460 HydrophobicContact CZ3-CD1 3.88Å; W286-Y460 HydrophobicContact CZ3-CD2 4.2Å; W286-Y460 HydrophobicContact CZ3-CE1 4.23Å; W286-Y460 AromaticContact CZ3-CG 3.87Å; W286-Y460 HydrophobicContact CZ3-CG 3.87Å; W286-F461 HydrophobicContact CB-CZ 4.3Å; W286-F461 HydrophobicContact CD2-CZ 4.4Å; W286-F461 HydrophobicContact CG-CZ 4.16Å
287	V	93.3	Very high	89.6	Confident	37 Å²	37	32.7 Å²	32.7	22%	0.224	17%	0.17	C	C	.	.	H	α-helix	trans	-66.4	-39.1	176.5	-176.9	0	0	0	0	110.8	V172 T175 W283 A285 G290 A291	V172-V287 HydrophobicContact CG2-CG1 4.13Å; T175-V287 HydrophobicContact CG2-CB 4.37Å; T175-V287 HydrophobicContact CG2-CG1 3.8Å; W283-V287 WeakPolarHBondContact O-CG2 3.49Å; W283-V287 PolarHBondContact O-N 3.26Å; A285-V287 VanDerWaalsContact C-N 3.35Å; A285-V287 PolarHBondContact O-N 3.22Å; V287-G290 PolarHBondContact O-N 2.91Å; V287-A291 VanDerWaalsContact O-CB 3.22Å; V287-A291 WeakPolarHBondContact O-CB 3.34Å; V287-A291 PolarHBondContact O-N 3.26Å
288	I	92.8	Very high	89.3	Confident	4 Å²	4	36 Å²	36	2%	0.021	19%	0.191	C	C	.	.	H	α-helix	trans	-61.2	-46.1	174.7	-96.7	176.7	0	0	0	111.4	T175 M178 L280 S284 A285 G290 A291 I292	T175-I288 HydrophobicContact CG2-CB 4.27Å; T175-I288 HydrophobicContact CG2-CG1 3.5Å; T175-I288 VanDerWaalsContact CG2-CG1 3.5Å; M178-I288 HydrophobicContact CB-CD1 3.76Å; M178-I288 HydrophobicContact CE-CD1 4.46Å; M178-I288 HydrophobicContact CG-CD1 4.2Å; L280-I288 HydrophobicContact CD1-CD1 4.34Å; L280-I288 HydrophobicContact CD1-CG2 4.34Å; L280-I288 HydrophobicContact CD2-CD1 3.73Å; S284-I288 VanDerWaalsContact O-CB 3.22Å; S284-I288 WeakPolarHBondContact O-CB 3.28Å; S284-I288 PolarHBondContact O-N 2.89Å; A285-I288 PolarHBondContact O-N 3.1Å; I288-G290 VanDerWaalsContact C-N 3.34Å; I288-G290 PolarHBondContact O-N 3.46Å; I288-A291 PolarHBondContact O-N 3.05Å; I288-I292 HydrophobicContact CG2-CD1 3.82Å; I288-I292 WeakPolarHBondContact O-CB 3.25Å; I288-I292 VanDerWaalsContact O-CG1 3.32Å; I288-I292 WeakPolarHBondContact O-CG1 3.31Å; I288-I292 PolarHBondContact O-N 2.89Å
289	L	92.8	Very high	88.8	Confident	2 Å²	2	35.2 Å²	35.2	1%	0.01	19%	0.188	C	C	.	.	H	α-helix	trans	-61.3	-45.2	-179.3	-73.1	170.5	0	0	0	110.8	A285 W286 S293 F402 V405 L406 I453 L457	A285-L289 WeakPolarHBondContact O-CG 3.35Å; A285-L289 PolarHBondContact O-N 3.36Å; W286-L289 HydrophobicContact CE3-CD1 4.12Å; W286-L289 HydrophobicContact CZ3-CD1 4.3Å; W286-L289 PolarHBondContact O-N 3.32Å; L289-S293 PolarHBondContact O-N 2.85Å; L289-S293 VanDerWaalsContact O-N 3.13Å; L289-S293 PolarHBondContact O-OG 3.06Å; L289-F402 HydrophobicContact CD2-CB 4.33Å; L289-F402 HydrophobicContact CD2-CD1 4Å; L289-V405 HydrophobicContact CD1-CG1 4.35Å; L289-V405 HydrophobicContact CD2-CB 4.36Å; L289-V405 HydrophobicContact CD2-CG1 4.07Å; L289-V405 HydrophobicContact CG-CG1 4.47Å; L289-L406 HydrophobicContact CD1-CB 4Å; L289-L406 HydrophobicContact CD1-CG 4.22Å; L289-I453 HydrophobicContact CB-CG2 4.32Å; L289-L457 HydrophobicContact CB-CD2 4.5Å
290	G	92.8	Very high	88.3	Confident	22 Å²	22	32.9 Å²	32.9	23%	0.227	18%	0.182	C	C	.	.	H	α-helix	trans	-67.7	-35	176	0	0	0	0	0	113.8	W286 V287 I288 S293 V294	W286-G290 PolarHBondContact O-N 3.29Å; W286-G290 VanDerWaalsContact O-N 3.13Å; V287-G290 PolarHBondContact O-N 2.91Å; I288-G290 VanDerWaalsContact C-N 3.34Å; I288-G290 PolarHBondContact O-N 3.46Å; G290-S293 PolarHBondContact O-OG 3.11Å; G290-V294 WeakPolarHBondContact O-CG2 3.36Å; G290-V294 PolarHBondContact O-N 2.99Å
291	A	92.3	Very high	87.9	Confident	34 Å²	34	36.8 Å²	36.8	28%	0.281	20%	0.203	S	C	.	.	H	α-helix	trans	-78.5	-33.3	-179.8	0	0	0	0	0	112.5	T175 I179 V287 I288 V294 Y295	T175-A291 HydrophobicContact CG2-CB 4.18Å; I179-A291 HydrophobicContact CD1-CB 3.25Å; V287-A291 VanDerWaalsContact O-CB 3.22Å; V287-A291 WeakPolarHBondContact O-CB 3.34Å; V287-A291 PolarHBondContact O-N 3.26Å; I288-A291 PolarHBondContact O-N 3.05Å; A291-V294 PolarHBondContact O-N 3.2Å; A291-Y295 WeakPolarHBondContact O-CB 3.19Å; A291-Y295 PolarHBondContact O-N 2.99Å
292	I	89.9	Confident	87.4	Confident	15 Å²	15	37.9 Å²	37.9	8%	0.077	21%	0.211	C	C	.	.	H	α-helix	trans	-69.4	-37.7	173.8	-70.4	177.1	0	0	0	111	I179 I182 I288 V294 Y295 D296 F402 L449	I179-I292 HydrophobicContact CD1-CG1 4.46Å; I179-I292 HydrophobicContact CG1-CG1 4.43Å; I182-I292 HydrophobicContact CD1-CD1 4.2Å; I288-I292 HydrophobicContact CG2-CD1 3.82Å; I288-I292 WeakPolarHBondContact O-CB 3.25Å; I288-I292 VanDerWaalsContact O-CG1 3.32Å; I288-I292 WeakPolarHBondContact O-CG1 3.31Å; I288-I292 PolarHBondContact O-N 2.89Å; I292-V294 VanDerWaalsContact C-N 3.34Å; I292-V294 PolarHBondContact O-N 2.87Å; I292-Y295 PolarHBondContact O-N 2.82Å; I292-D296 WeakPolarHBondContact O-CB 3.4Å; I292-D296 PolarHBondContact O-N 3.48Å; I292-F402 HydrophobicContact CD1-CD1 4.43Å; I292-F402 HydrophobicContact CD1-CE1 3.45Å; I292-F402 VanDerWaalsContact CD1-CE1 3.45Å; I292-F402 HydrophobicContact CD1-CZ 3.59Å; I292-F402 HydrophobicContact CG2-CD2 4.33Å; I292-F402 HydrophobicContact CG2-CE1 4.19Å; I292-F402 HydrophobicContact CG2-CE2 3.87Å; I292-F402 HydrophobicContact CG2-CZ 3.8Å; I292-L449 HydrophobicContact CG2-CD1 4.43Å
293	S	90.8	Very high	86.7	Confident	7 Å²	7	40.2 Å²	40.2	5%	0.049	23%	0.231	C	C	.	.	H	α-helix	trans	-61.2	-42	174	60.3	0	0	0	0	112.8	L289 G290 L297 L449	L289-S293 PolarHBondContact O-N 2.85Å; L289-S293 VanDerWaalsContact O-N 3.13Å; L289-S293 PolarHBondContact O-OG 3.06Å; G290-S293 PolarHBondContact O-OG 3.11Å; S293-L297 PolarHBondContact O-N 3.44Å; S293-L449 VanDerWaalsContact CA-CD2 3.5Å
294	V	89.6	Confident	86.1	Confident	88 Å²	88	45.7 Å²	45.7	53%	0.533	26%	0.257	S	S	.	.	H	α-helix	trans	-66.5	-42.1	173.5	175.7	0	0	0	0	111.1	G290 A291 I292 D296 L297 V298	G290-V294 WeakPolarHBondContact O-CG2 3.36Å; G290-V294 PolarHBondContact O-N 2.99Å; A291-V294 PolarHBondContact O-N 3.2Å; I292-V294 VanDerWaalsContact C-N 3.34Å; I292-V294 PolarHBondContact O-N 2.87Å; V294-D296 PolarHBondContact O-N 3.28Å; V294-L297 WeakPolarHBondContact O-CB 3.4Å; V294-L297 PolarHBondContact O-N 3.35Å; V294-V298 HydrophobicContact CG1-CG2 4.47Å; V294-V298 WeakPolarHBondContact O-CG2 3.15Å; V294-V298 PolarHBondContact O-N 3.31Å
295	Y	88.3	Confident	85.3	Confident	57 Å²	57	45.8 Å²	45.8	22%	0.224	26%	0.258	C	S	.	.	H	α-helix	trans	-61.3	-44.4	178.2	175.7	-99.2	0	0	0	112.4	V183 A291 I292 L297 V298 A299 L307	V183-Y295 HydrophobicContact CG2-CD2 4.21Å; V183-Y295 HydrophobicContact CG2-CE2 3.6Å; A291-Y295 WeakPolarHBondContact O-CB 3.19Å; A291-Y295 PolarHBondContact O-N 2.99Å; I292-Y295 PolarHBondContact O-N 2.82Å; Y295-L297 VanDerWaalsContact C-N 3.34Å; Y295-L297 PolarHBondContact O-N 2.95Å; Y295-V298 PolarHBondContact O-N 2.93Å; Y295-A299 HydrophobicContact CE1-CB 4.19Å; Y295-A299 VanDerWaalsContact O-CB 3.23Å; Y295-A299 WeakPolarHBondContact O-CB 3.3Å; Y295-A299 PolarHBondContact O-N 3.36Å; Y295-L307 HydrophobicContact CE1-CD1 4.47Å
296	D	86.3	Confident	84.4	Confident	28 Å²	28	47.2 Å²	47.2	15%	0.15	27%	0.268	C	S	.	.	H	α-helix	trans	-61.4	-43.3	178.3	-171.5	55.2	0	0	0	111.2	I292 V294 V298 A299 V300 P447	I292-D296 WeakPolarHBondContact O-CB 3.4Å; I292-D296 PolarHBondContact O-N 3.48Å; V294-D296 PolarHBondContact O-N 3.28Å; D296-V298 PolarHBondContact O-N 3.06Å; D296-A299 PolarHBondContact O-N 3.35Å; D296-V300 WeakPolarHBondContact O-CB 3.35Å; D296-V300 WeakPolarHBondContact O-CG2 3.31Å; D296-V300 PolarHBondContact O-N 2.99Å; D296-P447 WeakPolarHBondContact OD2-CB 3.49Å
297	L	83.4	Confident	83.3	Confident	68 Å²	68	49.2 Å²	49.2	36%	0.356	28%	0.279	S	S	.	.	H	α-helix	trans	-57.2	-47.4	173.9	-172.9	67.6	0	0	0	112.3	S293 V294 Y295 L301 P447 P450	S293-L297 PolarHBondContact O-N 3.44Å; V294-L297 WeakPolarHBondContact O-CB 3.4Å; V294-L297 PolarHBondContact O-N 3.35Å; Y295-L297 VanDerWaalsContact C-N 3.34Å; Y295-L297 PolarHBondContact O-N 2.95Å; L297-L301 HydrophobicContact CD1-CD1 3.46Å; L297-L301 VanDerWaalsContact CD1-CD1 3.46Å; L297-L301 HydrophobicContact CD1-CG 4.11Å; L297-L301 HydrophobicContact CG-CD1 3.88Å; L297-L301 VanDerWaalsContact O-CB 3.28Å; L297-L301 WeakPolarHBondContact O-CB 3.5Å; L297-L301 WeakPolarHBondContact O-CG 3.41Å; L297-L301 PolarHBondContact O-N 2.98Å; L297-P447 HydrophobicContact CD1-CG 3.74Å; L297-P450 HydrophobicContact CB-CG 4.41Å; L297-P450 HydrophobicContact CD1-CG 4.3Å
298	V	84.8	Confident	82.2	Confident	76 Å²	76	52 Å²	52	46%	0.461	29%	0.286	S	S	.	.	H	α-helix	trans	-68	-42.8	179.3	173.1	0	0	0	0	111.1	V294 Y295 D296 V300 C302	V294-V298 HydrophobicContact CG1-CG2 4.47Å; V294-V298 WeakPolarHBondContact O-CG2 3.15Å; V294-V298 PolarHBondContact O-N 3.31Å; Y295-V298 PolarHBondContact O-N 2.93Å; D296-V298 PolarHBondContact O-N 3.06Å; V298-V300 VanDerWaalsContact C-N 3.3Å; V298-V300 PolarHBondContact O-N 3.41Å; V298-C302 WeakPolarHBondContact O-CB 3.28Å; V298-C302 PolarHBondContact O-N 3.22Å; V298-C302 PolarHBondContact O-SG 3Å
299	A	80.6	Confident	81	Confident	4 Å²	4	54.9 Å²	54.9	3%	0.033	30%	0.3	C	S	.	.	H	α-helix	trans	-70.9	-24.3	-176.3	0	0	0	0	0	113.5	Y295 D296 G305 L307	Y295-A299 HydrophobicContact CE1-CB 4.19Å; Y295-A299 VanDerWaalsContact O-CB 3.23Å; Y295-A299 WeakPolarHBondContact O-CB 3.3Å; Y295-A299 PolarHBondContact O-N 3.36Å; D296-A299 PolarHBondContact O-N 3.35Å; A299-G305 WeakPolarHBondContact O-CA 2.87Å; A299-L307 HydrophobicContact CB-CB 4.44Å; A299-L307 HydrophobicContact CB-CD1 3.71Å
300	V	76.3	Confident	80	Confident	38 Å²	38	56.6 Å²	56.6	23%	0.23	31%	0.309	C	S	.	.	H	α-helix	trans	-90.1	-45.7	175.1	175.3	0	0	0	0	111.8	D296 V298 P447	D296-V300 WeakPolarHBondContact O-CB 3.35Å; D296-V300 WeakPolarHBondContact O-CG2 3.31Å; D296-V300 PolarHBondContact O-N 2.99Å; V298-V300 VanDerWaalsContact C-N 3.3Å; V298-V300 PolarHBondContact O-N 3.41Å; V300-P447 HydrophobicContact CB-CB 4.36Å; V300-P447 HydrophobicContact CB-CG 4.29Å; V300-P447 HydrophobicContact CG1-CG 4.41Å; V300-P447 HydrophobicContact CG2-CB 4.21Å
301	L	77.4	Confident	78.8	Confident	92 Å²	92	59 Å²	59	48%	0.482	32%	0.32	S	S	.	.	H	α-helix	trans	-76.5	-30.3	-175.9	-66.9	-179.1	0	0	0	113.3	L297	L297-L301 HydrophobicContact CD1-CD1 3.46Å; L297-L301 VanDerWaalsContact CD1-CD1 3.46Å; L297-L301 HydrophobicContact CD1-CG 4.11Å; L297-L301 HydrophobicContact CG-CD1 3.88Å; L297-L301 VanDerWaalsContact O-CB 3.28Å; L297-L301 WeakPolarHBondContact O-CB 3.5Å; L297-L301 WeakPolarHBondContact O-CG 3.41Å; L297-L301 PolarHBondContact O-N 2.98Å
302	C	76.6	Confident	77.8	Confident	56 Å²	56	60.9 Å²	60.9	38%	0.378	32%	0.322	S	S	.	.	S	Bend	trans	-73.7	133.1	180	-68	0	0	0	0	111.7	V298 K304 G305	V298-C302 WeakPolarHBondContact O-CB 3.28Å; V298-C302 PolarHBondContact O-N 3.22Å; V298-C302 PolarHBondContact O-SG 3Å; C302-K304 PolarHBondContact O-N 3.45Å; C302-G305 PolarHBondContact O-N 2.89Å
303	P	70.6	Confident	76.5	Confident	106 Å²	106	61.3 Å²	61.3	69%	0.688	33%	0.326	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.9	-7.3	-177.5	27.2	-35.7	0	0	0	114.5
304	K	74.9	Confident	75.1	Confident	201 Å²	201	61.4 Å²	61.4	87%	0.874	33%	0.327	S	S	*	.	T	Hydrogen-bonded Turn	trans	-117.2	20.1	174.8	-66.4	-177.9	177.1	169.3	0	112.4	C302	C302-K304 PolarHBondContact O-N 3.45Å
305	G	75.6	Confident	73.7	Confident	4 Å²	4	63.6 Å²	63.6	4%	0.041	33%	0.331	C	S	.	.			trans	-67	139	179.1	0	0	0	0	0	112	A299 C302 L307 R308 M309	A299-G305 WeakPolarHBondContact O-CA 2.87Å; C302-G305 PolarHBondContact O-N 2.89Å; G305-L307 VanDerWaalsContact C-N 3.3Å; G305-L307 PolarHBondContact O-N 3.1Å; G305-R308 PolarHBondContact O-N 3.42Å; G305-M309 WeakPolarHBondContact O-CB 3.31Å; G305-M309 PolarHBondContact O-N 2.86Å
306	P	71.8	Confident	72.5	Confident	30 Å²	30	68 Å²	68	20%	0.195	35%	0.354	C	S	.	.	H	α-helix	trans	-63.2	-36.5	-179.3	22.9	-31.6	0	0	0	112.6	V190 L310	V190-P306 HydrophobicContact CG2-CB 3.83Å; P306-L310 WeakPolarHBondContact O-CG 3.42Å; P306-L310 PolarHBondContact O-N 3.03Å; P306-L310 VanDerWaalsContact O-N 3.08Å
307	L	68.1	Low	71.1	Confident	64 Å²	64	70.8 Å²	70.8	34%	0.335	36%	0.362	S	S	.	.	H	α-helix	trans	-68.3	-46.5	177.1	-82	152.8	0	0	0	111.2	Y295 A299 G305 M309 L310 V311	Y295-L307 HydrophobicContact CE1-CD1 4.47Å; A299-L307 HydrophobicContact CB-CB 4.44Å; A299-L307 HydrophobicContact CB-CD1 3.71Å; G305-L307 VanDerWaalsContact C-N 3.3Å; G305-L307 PolarHBondContact O-N 3.1Å; L307-M309 PolarHBondContact O-N 3.33Å; L307-L310 WeakPolarHBondContact O-CB 3.33Å; L307-L310 PolarHBondContact O-N 3.34Å; L307-V311 WeakPolarHBondContact O-CG2 3.41Å; L307-V311 PolarHBondContact O-N 3.49Å
308	R	71.4	Confident	69.6	Low	96 Å²	96	74.8 Å²	74.8	36%	0.362	38%	0.384	S	S	.	.	H	α-helix	trans	-61.1	-42.8	175.2	-174.5	171.1	175.6	164.6	2	112.3	G305 L310 V311 E312	G305-R308 PolarHBondContact O-N 3.42Å; R308-L310 VanDerWaalsContact C-N 3.32Å; R308-L310 PolarHBondContact O-N 2.87Å; R308-V311 PolarHBondContact O-N 3.48Å; R308-E312 HydrophobicContact CG-CG 4.27Å; R308-E312 WeakPolarHBondContact CG-OE1 3.5Å; R308-E312 IonicContact CZ-OE1 2.96Å; R308-E312 IonicContact NE-OE1 3.62Å; R308-E312 PolarHBondContact NE-OE1 3.37Å; R308-E312 IonicContact NH2-OE1 3.33Å; R308-E312 PolarHBondContact NH2-OE1 2.95Å; R308-E312 WeakPolarHBondContact O-CB 3.36Å; R308-E312 WeakPolarHBondContact O-CG 3.19Å; R308-E312 PolarHBondContact O-N 3.25Å
309	M	68	Low	68.3	Low	64 Å²	64	74.5 Å²	74.5	32%	0.315	38%	0.378	S	S	.	.	H	α-helix	trans	-61.7	-39.3	176.2	-170.4	-173.7	122.6	0	0	112	V190 K194 G305 L307 T313	V190-M309 HydrophobicContact CG1-CE 3.56Å; V190-M309 HydrophobicContact CG1-SD 4.24Å; K194-M309 HydrophobicContact CB-CE 4.44Å; K194-M309 HydrophobicContact CD-CE 4.03Å; G305-M309 WeakPolarHBondContact O-CB 3.31Å; G305-M309 PolarHBondContact O-N 2.86Å; L307-M309 PolarHBondContact O-N 3.33Å; M309-T313 VanDerWaalsContact O-CB 3.24Å; M309-T313 WeakPolarHBondContact O-CB 3.31Å; M309-T313 PolarHBondContact O-N 3.37Å; M309-T313 PolarHBondContact O-OG1 3.4Å
310	L	70.1	Confident	67.1	Low	39 Å²	39	80.1 Å²	80.1	20%	0.204	41%	0.414	C	S	.	.	H	α-helix	trans	-64.5	-44.2	174.6	-81.6	170.3	0	0	0	112.1	L189 V190 Y193 P306 L307 R308 A314	L189-L310 HydrophobicContact CD2-CD1 4.21Å; L189-L310 HydrophobicContact CD2-CD2 4.39Å; V190-L310 HydrophobicContact CB-CG 4.45Å; V190-L310 HydrophobicContact CG1-CG 4.45Å; V190-L310 HydrophobicContact CG2-CD1 3.51Å; V190-L310 HydrophobicContact CG2-CD2 4.31Å; V190-L310 HydrophobicContact CG2-CG 3.75Å; Y193-L310 HydrophobicContact CD1-CD2 3.6Å; Y193-L310 HydrophobicContact CD2-CD2 4.49Å; Y193-L310 HydrophobicContact CE1-CD2 4.2Å; Y193-L310 HydrophobicContact CG-CD2 3.76Å; P306-L310 WeakPolarHBondContact O-CG 3.42Å; P306-L310 PolarHBondContact O-N 3.03Å; P306-L310 VanDerWaalsContact O-N 3.08Å; L307-L310 WeakPolarHBondContact O-CB 3.33Å; L307-L310 PolarHBondContact O-N 3.34Å; R308-L310 VanDerWaalsContact C-N 3.32Å; R308-L310 PolarHBondContact O-N 2.87Å; L310-A314 VanDerWaalsContact O-CB 3.27Å; L310-A314 WeakPolarHBondContact O-CB 3.01Å; L310-A314 PolarHBondContact O-N 2.75Å
311	V	68.6	Low	66.3	Low	73 Å²	73	81.9 Å²	81.9	44%	0.442	42%	0.421	S	S	.	.	H	α-helix	trans	-65.3	-49.3	179.8	174	0	0	0	0	110.9	L307 R308 T313 A314 Q315	L307-V311 WeakPolarHBondContact O-CG2 3.41Å; L307-V311 PolarHBondContact O-N 3.49Å; R308-V311 PolarHBondContact O-N 3.48Å; V311-T313 PolarHBondContact O-N 2.97Å; V311-A314 PolarHBondContact O-N 3Å; V311-Q315 HydrophobicContact CG1-CG 4.5Å; V311-Q315 WeakPolarHBondContact O-CB 3.48Å; V311-Q315 WeakPolarHBondContact O-CG 3.31Å; V311-Q315 PolarHBondContact O-N 3.05Å
312	E	71.6	Confident	65.6	Low	72 Å²	72	79.5 Å²	79.5	34%	0.336	41%	0.407	S	S	.	.	H	α-helix	trans	-61.9	-45.4	179.1	-71.6	172.9	174.9	0	0	110.9	R308 A314 Q315 E316	R308-E312 HydrophobicContact CG-CG 4.27Å; R308-E312 WeakPolarHBondContact CG-OE1 3.5Å; R308-E312 IonicContact CZ-OE1 2.96Å; R308-E312 IonicContact NE-OE1 3.62Å; R308-E312 PolarHBondContact NE-OE1 3.37Å; R308-E312 IonicContact NH2-OE1 3.33Å; R308-E312 PolarHBondContact NH2-OE1 2.95Å; R308-E312 WeakPolarHBondContact O-CB 3.36Å; R308-E312 WeakPolarHBondContact O-CG 3.19Å; R308-E312 PolarHBondContact O-N 3.25Å; E312-A314 VanDerWaalsContact C-N 3.31Å; E312-A314 PolarHBondContact O-N 3.34Å; E312-Q315 PolarHBondContact O-N 2.86Å; E312-E316 WeakPolarHBondContact O-CB 3.23Å; E312-E316 VanDerWaalsContact O-CG 3.31Å; E312-E316 WeakPolarHBondContact O-CG 3.07Å; E312-E316 PolarHBondContact O-N 3.12Å
313	T	62.3	Low	64.7	Low	24 Å²	24	80.1 Å²	80.1	15%	0.147	41%	0.411	C	S	.	.	H	α-helix	trans	-67.8	-29.4	179.1	-49.8	0	0	0	0	112.6	Y193 M309 V311 R317	Y193-T313 HydrophobicContact CD1-CG2 4.43Å; Y193-T313 HydrophobicContact CE1-CG2 3.7Å; M309-T313 VanDerWaalsContact O-CB 3.24Å; M309-T313 WeakPolarHBondContact O-CB 3.31Å; M309-T313 PolarHBondContact O-N 3.37Å; M309-T313 PolarHBondContact O-OG1 3.4Å; V311-T313 PolarHBondContact O-N 2.97Å; T313-R317 WeakPolarHBondContact O-CG 3.29Å
314	A	60.7	Low	64.2	Low	10 Å²	10	76.2 Å²	76.2	8%	0.083	39%	0.387	C	S	.	.	H	α-helix	trans	-74.1	-39.8	174.6	0	0	0	0	0	111.7	L310 V311 E312 R317 N318 I321	L310-A314 VanDerWaalsContact O-CB 3.27Å; L310-A314 WeakPolarHBondContact O-CB 3.01Å; L310-A314 PolarHBondContact O-N 2.75Å; V311-A314 PolarHBondContact O-N 3Å; E312-A314 VanDerWaalsContact C-N 3.31Å; E312-A314 PolarHBondContact O-N 3.34Å; A314-R317 PolarHBondContact O-N 3.31Å; A314-N318 PolarHBondContact O-N 2.68Å; A314-I321 HydrophobicContact CB-CG1 4.21Å
315	Q	61.1	Low	63.9	Low	133 Å²	133	70.4 Å²	70.4	62%	0.621	37%	0.365	S	S	*	.	H	α-helix	trans	-66.2	-40.6	175.7	-73.4	178.8	-37.4	0	0	112.2	V311 E312 R317	V311-Q315 HydrophobicContact CG1-CG 4.5Å; V311-Q315 WeakPolarHBondContact O-CB 3.48Å; V311-Q315 WeakPolarHBondContact O-CG 3.31Å; V311-Q315 PolarHBondContact O-N 3.05Å; E312-Q315 PolarHBondContact O-N 2.86Å; Q315-R317 PolarHBondContact O-N 2.98Å
316	E	63.5	Low	63.9	Low	149 Å²	149	72.3 Å²	72.3	70%	0.696	37%	0.374	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.2	-24.1	175.5	-76.9	174.7	-175.4	0	0	113.5	E312	E312-E316 WeakPolarHBondContact O-CB 3.23Å; E312-E316 VanDerWaalsContact O-CG 3.31Å; E312-E316 WeakPolarHBondContact O-CG 3.07Å; E312-E316 PolarHBondContact O-N 3.12Å
317	R	55.2	Low	64	Low	87 Å²	87	71.2 Å²	71.2	33%	0.328	37%	0.366	S	S	.	.	T	Hydrogen-bonded Turn	trans	-108.9	-2.1	-172.3	-65.5	-168.7	-175.1	-169.8	10.3	115	Y198 T313 A314 Q315 E319	Y198-R317 PolarHBondContact OH-NH1 3.45Å; T313-R317 WeakPolarHBondContact O-CG 3.29Å; A314-R317 PolarHBondContact O-N 3.31Å; Q315-R317 PolarHBondContact O-N 2.98Å; R317-E319 HydrophobicContact CB-CG 4.18Å; R317-E319 PolarHBondContact O-N 3.5Å; R317-E319 VanDerWaalsContact O-N 3.09Å
318	N	53.1	Low	64.3	Low	152 Å²	152	69.8 Å²	69.8	81%	0.813	36%	0.361	S	S	*	.	T	Hydrogen-bonded Turn	trans	49.8	31	-176.1	-69.2	-57.9	0	0	0	113.4	A314	A314-N318 PolarHBondContact O-N 2.68Å
319	E	56.8	Low	63.6	Low	71 Å²	71	65.8 Å²	65.8	33%	0.332	35%	0.348	S	S	.	.	P	Polyproline II helix	trans	-88.4	133.7	177.1	-73.1	174.9	-164.3	0	0	109.2	Y198 R317 I321	Y198-E319 WeakPolarHBondContact CE1-OE2 3.47Å; Y198-E319 PolarHBondContact OH-OE1 3.42Å; Y198-E319 VanDerWaalsContact OH-OE1 3.05Å; Y198-E319 PolarHBondContact OH-OE2 2.96Å; Y198-E319 VanDerWaalsContact OH-OE2 3.08Å; R317-E319 HydrophobicContact CB-CG 4.18Å; R317-E319 PolarHBondContact O-N 3.5Å; R317-E319 VanDerWaalsContact O-N 3.09Å; E319-I321 PolarHBondContact O-N 3.14Å; E319-I321 VanDerWaalsContact O-N 3.1Å
320	P	55.1	Low	62.9	Low	122 Å²	122	63.3 Å²	63.3	79%	0.792	34%	0.338	S	S	*	.	P	Polyproline II helix	trans	-61.5	118.7	177.7	24.8	-32.4	0	0	0	109.3	F322	P320-F322 PolarHBondContact O-N 3.27Å
321	I	60.4	Low	61.6	Low	75 Å²	75	68.2 Å²	68.2	39%	0.385	36%	0.361	S	S	.	.	P	Polyproline II helix	trans	-59	139.5	180	-51.3	168.5	0	0	0	109.1	A314 E319 P323 I326	A314-I321 HydrophobicContact CB-CG1 4.21Å; E319-I321 PolarHBondContact O-N 3.14Å; E319-I321 VanDerWaalsContact O-N 3.1Å; I321-P323 WeakPolarHBondContact O-CD 3.46Å; I321-P323 VanDerWaalsContact O-N 3.13Å; I321-I326 HydrophobicContact CB-CD1 3.89Å; I321-I326 HydrophobicContact CD1-CD1 4.01Å; I321-I326 HydrophobicContact CG2-CD1 3.34Å; I321-I326 HydrophobicContact CG2-CG1 4.23Å
322	F	62.8	Low	60.1	Low	42 Å²	42	69.1 Å²	69.1	18%	0.184	37%	0.367	C	S	.	.			trans	-43.1	115	-171.7	-62.5	-69.2	0	0	0	113.1	Y193 I201 L205 P320 A324 L325	Y193-F322 HydrophobicContact CD2-CE2 4.17Å; Y193-F322 HydrophobicContact CD2-CZ 4.1Å; Y193-F322 HydrophobicContact CE2-CE2 4.23Å; Y193-F322 HydrophobicContact CE2-CZ 4.19Å; I201-F322 HydrophobicContact CB-CZ 4.48Å; I201-F322 HydrophobicContact CG2-CD1 4.47Å; I201-F322 HydrophobicContact CG2-CE1 3.6Å; I201-F322 HydrophobicContact CG2-CE2 4.19Å; I201-F322 HydrophobicContact CG2-CZ 3.45Å; I201-F322 VanDerWaalsContact CG2-CZ 3.45Å; L205-F322 HydrophobicContact CD1-CB 3.87Å; L205-F322 HydrophobicContact CD1-CD1 3.43Å; L205-F322 VanDerWaalsContact CD1-CD1 3.43Å; L205-F322 HydrophobicContact CD1-CD2 4.29Å; L205-F322 HydrophobicContact CD1-CE1 4.04Å; L205-F322 HydrophobicContact CD1-CG 3.59Å; P320-F322 PolarHBondContact O-N 3.27Å; F322-A324 PolarHBondContact O-N 3.2Å; F322-L325 HydrophobicContact CB-CB 4.38Å; F322-L325 HydrophobicContact CB-CD1 3.89Å; F322-L325 HydrophobicContact CB-CG 4.49Å; F322-L325 HydrophobicContact CD2-CD1 4.11Å; F322-L325 HydrophobicContact CG-CD1 4.29Å; F322-L325 PolarHBondContact O-N 3.49Å
323	P	56.5	Low	58.2	Low	69 Å²	69	71.9 Å²	71.9	45%	0.448	37%	0.374	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.5	-26.8	-174.3	-27.6	34	0	0	0	114.6	I252 I321 L325	I252-P323 WeakPolarHBondContact O-CB 3.35Å; I321-P323 WeakPolarHBondContact O-CD 3.46Å; I321-P323 VanDerWaalsContact O-N 3.13Å; P323-L325 VanDerWaalsContact C-N 3.33Å; P323-L325 PolarHBondContact O-N 2.95Å
324	A	60.4	Low	56.7	Low	24 Å²	24	77 Å²	77	20%	0.198	41%	0.406	C	S	.	.	T	Hydrogen-bonded Turn	trans	-81.8	-3.9	-178.7	0	0	0	0	0	114.6	I252 F322 L397	I252-A324 HydrophobicContact CG2-CB 3.64Å; F322-A324 PolarHBondContact O-N 3.2Å; A324-L397 WeakPolarHBondContact O-CD1 3.26Å
325	L	68.4	Low	55.5	Low	79 Å²	79	81.5 Å²	81.5	41%	0.414	43%	0.432	S	S	.	.	T	Hydrogen-bonded Turn	trans	-114.1	-17.7	-174.2	-80.5	163.2	0	0	0	113.9	L205 F322 P323 L397	L205-L325 HydrophobicContact CD1-CD1 4.31Å; L205-L325 HydrophobicContact CD2-CD1 4.26Å; F322-L325 HydrophobicContact CB-CB 4.38Å; F322-L325 HydrophobicContact CB-CD1 3.89Å; F322-L325 HydrophobicContact CB-CG 4.49Å; F322-L325 HydrophobicContact CD2-CD1 4.11Å; F322-L325 HydrophobicContact CG-CD1 4.29Å; F322-L325 PolarHBondContact O-N 3.49Å; P323-L325 VanDerWaalsContact C-N 3.33Å; P323-L325 PolarHBondContact O-N 2.95Å; L325-L397 WeakPolarHBondContact O-CG 3.28Å; L325-L397 PolarHBondContact O-N 3.39Å
326	I	75.9	Confident	54.2	Low	43 Å²	43	78.5 Å²	78.5	22%	0.221	44%	0.437	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.7	133.5	-175.2	-62.4	-174.5	0	0	0	110	I321 K394	I321-I326 HydrophobicContact CB-CD1 3.89Å; I321-I326 HydrophobicContact CD1-CD1 4.01Å; I321-I326 HydrophobicContact CG2-CD1 3.34Å; I321-I326 HydrophobicContact CG2-CG1 4.23Å; I326-K394 HydrophobicContact CG2-CB 3.69Å; I326-K394 HydrophobicContact CG2-CD 4.2Å; I326-K394 HydrophobicContact CG2-CG 4.08Å
327	Y	75.2	Confident	52.6	Low	7 Å²	7	80.1 Å²	80.1	3%	0.027	45%	0.447	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82	120.9	167.2	-176.7	-92.5	0	0	0	109.7	P127 Q262 L265 K394 L395 F400	P127-Y327 HydrophobicContact CB-CE1 4.25Å; P127-Y327 HydrophobicContact CB-CE2 3.98Å; P127-Y327 WeakPolarHBondContact CB-OH 3.45Å; P127-Y327 HydrophobicContact CG-CE1 3.74Å; P127-Y327 HydrophobicContact CG-CE2 4.38Å; P127-Y327 WeakPolarHBondContact CG-OH 3.39Å; Q262-Y327 HydrophobicContact CB-CE2 3.8Å; Q262-Y327 VanDerWaalsContact CD-OH 3.27Å; Q262-Y327 HydrophobicContact CG-CE2 3.64Å; L265-Y327 HydrophobicContact CB-CD2 4.33Å; L265-Y327 HydrophobicContact CD1-CD2 4.12Å; Y327-K394 WeakPolarHBondContact O-CA 3.22Å; Y327-L395 WeakPolarHBondContact CB-O 3.44Å; Y327-L395 PolarHBondContact N-O 3.03Å; Y327-L395 PolarHBondContact O-N 3.46Å; Y327-F400 HydrophobicContact CD1-CE2 4.37Å; Y327-F400 AromaticContact CD1-CZ 3.89Å; Y327-F400 HydrophobicContact CD1-CZ 3.89Å; Y327-F400 HydrophobicContact CD2-CZ 4.04Å; Y327-F400 HydrophobicContact CE1-CZ 4.39Å; Y327-F400 AromaticContact CG-CE2 4Å; Y327-F400 HydrophobicContact CG-CE2 4Å; Y327-F400 AromaticContact CG-CZ 3.71Å; Y327-F400 HydrophobicContact CG-CZ 3.71Å
328	S	73.9	Confident	51.4	Low	34 Å²	34	80.3 Å²	80.3	24%	0.238	47%	0.467	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.3	120.4	173.4	-169.1	0	0	0	0	110	Q262	Q262-S328 PolarHBondContact NE2-O 3.2Å
329	S	56	Low	50.2	Low	12 Å²	12	81.9 Å²	81.9	8%	0.084	47%	0.466	C	S	.	.			trans	-85.1	-25.2	-179.9	60.4	0	0	0	0	113.8	V393	S329-V393 PolarHBondContact OG-N 2.92Å; S329-V393 PolarHBondContact OG-O 3.32Å
330	A	53.6	Low	48.9	Very low	12 Å²	12	86 Å²	86	10%	0.099	49%	0.49	C	S	.	.	S	Bend	trans	-93.5	154.8	-179.4	0	0	0	0	0	114.7	V332 E390 G392	A330-V332 PolarHBondContact O-N 3.1Å; A330-V332 VanDerWaalsContact O-N 3.07Å; A330-E390 WeakPolarHBondContact CB-O 3.46Å; A330-G392 VanDerWaalsContact CB-N 3.34Å
331	M	41.8	Very low	47.6	Very low	142 Å²	142	85 Å²	85	70%	0.7	48%	0.477	S	S	*	.			trans	-70.1	91.9	178.3	-59.1	178.4	-173.1	0	0	111.1	L258 W333	L258-M331 VanDerWaalsContact CD1-CA 3.5Å; L258-M331 HydrophobicContact CD1-CB 3.97Å; L258-M331 HydrophobicContact CD1-CG 4.18Å; M331-W333 PolarHBondContact O-N 2.92Å
332	V	38.7	Very low	46.2	Very low	92 Å²	92	87.6 Å²	87.6	56%	0.558	50%	0.499	S	S	*	.			trans	-87.8	90.4	164.4	177.7	0	0	0	0	107.7	A330	A330-V332 PolarHBondContact O-N 3.1Å; A330-V332 VanDerWaalsContact O-N 3.07Å
333	W	30.1	Very low	44.7	Very low	130 Å²	130	90.3 Å²	90.3	49%	0.492	52%	0.524	S	S	.	.			trans	-120.7	83.3	158.3	-70.5	113	0	0	0	109.1	G256 L258 M331 V335	G256-W333 WeakPolarHBondContact O-CH2 3.36Å; L258-W333 HydrophobicContact CD1-CG 4.46Å; L258-W333 VanDerWaalsContact CD1-NE1 3.35Å; L258-W333 HydrophobicContact CG-CZ2 4.41Å; M331-W333 PolarHBondContact O-N 2.92Å; W333-V335 HydrophobicContact CB-CG2 4.45Å; W333-V335 HydrophobicContact CD2-CG2 4.45Å; W333-V335 HydrophobicContact CE3-CG2 3.7Å; W333-V335 HydrophobicContact CZ3-CG2 4.36Å; W333-V335 PolarHBondContact O-N 2.53Å
334	T	31.9	Very low	43.6	Very low	132 Å²	132	91.9 Å²	91.9	81%	0.81	54%	0.536	S	S	*	.			trans	-75.2	66.3	151.3	50.2	0	0	0	0	108.5
335	V	34.3	Very low	42.1	Very low	105 Å²	105	100.6 Å²	100.6	64%	0.636	57%	0.573	S	S	*	*			trans	-84.3	111.1	156.9	175	0	0	0	0	104.9	W333 M337	W333-V335 HydrophobicContact CB-CG2 4.45Å; W333-V335 HydrophobicContact CD2-CG2 4.45Å; W333-V335 HydrophobicContact CE3-CG2 3.7Å; W333-V335 HydrophobicContact CZ3-CG2 4.36Å; W333-V335 PolarHBondContact O-N 2.53Å; V335-M337 PolarHBondContact O-N 2.69Å
336	G	35.1	Very low	40.2	Very low	70 Å²	70	100.1 Å²	100.1	72%	0.722	59%	0.587	S	S	*	*			trans	-50.7	107.9	178.7	0	0	0	0	0	111.5	A338	G336-A338 PolarHBondContact O-N 2.76Å
337	M	28.7	Very low	38	Very low	183 Å²	183	102.9 Å²	102.9	90%	0.901	62%	0.616	S	S	*	*			trans	-68.9	111.6	146.6	-87.6	-77.3	145.4	0	0	105.9	V335 K339	V335-M337 PolarHBondContact O-N 2.69Å; M337-K339 PolarHBondContact O-N 3.36Å; M337-K339 VanDerWaalsContact O-N 3.15Å
338	A	30.8	Very low	35.8	Very low	90 Å²	90	111.2 Å²	111.2	74%	0.744	66%	0.66	S	S	*	*			trans	-51.9	118.1	179.7	0	0	0	0	0	109.9	G336 L340	G336-A338 PolarHBondContact O-N 2.76Å; A338-L340 PolarHBondContact O-N 3.38Å
339	K	28.5	Very low	33.6	Very low	185 Å²	185	118.2 Å²	118.2	80%	0.804	69%	0.689	S	S	*	*			trans	-65.6	103.3	159.7	-152	170.3	-170.9	160.6	0	105.9	M337 D341	M337-K339 PolarHBondContact O-N 3.36Å; M337-K339 VanDerWaalsContact O-N 3.15Å; K339-D341 VanDerWaalsContact C-N 3.34Å; K339-D341 PolarHBondContact O-N 3.02Å; K339-D341 VanDerWaalsContact O-N 3.14Å
340	L	29.3	Very low	32.2	Very low	158 Å²	158	125.4 Å²	125.4	83%	0.827	73%	0.726	S	S	*	*			trans	-70.4	99.4	162.5	-115.2	142.4	0	0	0	105.2	A338 P342	A338-L340 PolarHBondContact O-N 3.38Å; L340-P342 VanDerWaalsContact O-CD 3.25Å; L340-P342 WeakPolarHBondContact O-CD 3.37Å
341	D	26.4	Very low	30.9	Very low	100 Å²	100	130.6 Å²	130.6	54%	0.535	76%	0.758	S	S	.	*			trans	-70.5	115.9	167.3	-76	-35.6	0	0	0	108.3	K339 S343	K339-D341 VanDerWaalsContact C-N 3.34Å; K339-D341 PolarHBondContact O-N 3.02Å; K339-D341 VanDerWaalsContact O-N 3.14Å; D341-S343 VanDerWaalsContact C-N 3.26Å; D341-S343 PolarHBondContact O-N 2.81Å
342	P	32.8	Very low	30.1	Very low	130 Å²	130	133.4 Å²	133.4	84%	0.844	76%	0.763	S	S	*	*			trans	-89.1	69.3	166.5	30.2	-16.8	0	0	0	108	L340	L340-P342 VanDerWaalsContact O-CD 3.25Å; L340-P342 WeakPolarHBondContact O-CD 3.37Å
343	S	31	Very low	29.6	Very low	100 Å²	100	133.7 Å²	133.7	70%	0.699	76%	0.761	S	S	*	*			trans	-148.2	22.1	178.7	65.5	0	0	0	0	114.9	D341	D341-S343 VanDerWaalsContact C-N 3.26Å; D341-S343 PolarHBondContact O-N 2.81Å
344	S	32.8	Very low	30.1	Very low	102 Å²	102	132.2 Å²	132.2	71%	0.713	77%	0.768	S	S	*	*			trans	-135.9	55.8	175.1	36.3	0	0	0	0	113
345	Q	29.5	Very low	29.8	Very low	207 Å²	207	134.8 Å²	134.8	97%	0.967	77%	0.771	S	S	*	*			trans	-126.4	73.9	152.9	-75.4	-173.7	0.1	0	0	109
346	G	27.5	Very low	29.4	Very low	69 Å²	69	136.5 Å²	136.5	71%	0.711	77%	0.774	S	S	*	*			trans	-141.8	122.7	168.5	0	0	0	0	0	108.7
347	A	29.7	Very low	29.1	Very low	100 Å²	100	141 Å²	141	83%	0.826	78%	0.776	S	S	*	*			trans	76.4	86.2	168.7	0	0	0	0	0	117.7
348	L	29.7	Very low	29	Very low	182 Å²	182	139.6 Å²	139.6	95%	0.953	77%	0.768	S	S	*	*			trans	-125.5	116.1	135.7	-114.3	167.6	0	0	0	108.7
349	Q	28.3	Very low	28.7	Very low	182 Å²	182	141.3 Å²	141.3	85%	0.85	76%	0.764	S	S	*	*			trans	-80.6	140.2	-174.5	-127.3	151.2	-3.3	0	0	110.5
350	L	25.6	Very low	28.6	Very low	162 Å²	162	135.3 Å²	135.3	85%	0.848	75%	0.746	S	S	*	*			trans	-56	162.6	175.1	-85.3	163.6	0	0	0	114.4
351	P	26.7	Very low	28.7	Very low	121 Å²	121	137.9 Å²	137.9	79%	0.786	75%	0.746	S	S	*	*				-137.1	130.5	105.8	16.2	5.3	0	0	0	116.1
352	Y	25.4	Very low	28.6	Very low	201 Å²	201	140.2 Å²	140.2	79%	0.788	76%	0.758	S	S	*	*			trans	19.1	139.8	135.8	-134.6	-127.3	0	0	0	118.9
353	D	27.2	Very low	28.4	Very low	99 Å²	99	138.5 Å²	138.5	53%	0.529	75%	0.749	S	S	.	*			cis	-179	-163.5	21.6	-153.5	22	0	0	0	109
354	P	40.6	Very low	28.3	Very low	98 Å²	98	143.2 Å²	143.2	64%	0.636	76%	0.757	S	S	*	*				-115.4	167	-79.3	33.9	-15.9	0	0	0	113.7
355	E	25.9	Very low	27.9	Very low	187 Å²	187	141.8 Å²	141.8	87%	0.874	76%	0.759	S	S	*	*			trans	161.4	137.6	155.4	-94.6	165.3	-178.2	0	0	106.8
356	M	26.7	Very low	27.8	Very low	141 Å²	141	141.3 Å²	141.3	70%	0.695	76%	0.757	S	S	*	*			cis	-179.5	145.3	-7.8	173.3	175.7	-74.5	0	0	104.3
357	E	27.7	Very low	28.2	Very low	164 Å²	164	143.4 Å²	143.4	77%	0.766	76%	0.758	S	S	*	*			trans	67	150.5	161.8	-74.9	162.4	-165.5	0	0	119.4
358	E	26.1	Very low	28	Very low	154 Å²	154	143.1 Å²	143.1	72%	0.72	75%	0.75	S	S	*	*			cis	-174.9	153.3	-27.1	-140.1	-179.6	-177.7	0	0	104
359	D	25.4	Very low	28.1	Very low	125 Å²	125	144.4 Å²	144.4	67%	0.668	74%	0.744	S	S	*	*			trans	69.9	144.8	153.9	-64.9	-13.2	0	0	0	121.3
360	S	26.8	Very low	28.2	Very low	60 Å²	60	141.4 Å²	141.4	42%	0.42	74%	0.74	S	S	.	*			cis	165.1	143.4	-15.2	53.5	0	0	0	0	109.6
361	Y	30.2	Very low	28.5	Very low	211 Å²	211	143.2 Å²	143.2	83%	0.827	74%	0.744	S	S	*	*			trans	57.9	152.3	161.7	-6.7	-80.4	0	0	0	119.5
362	D	25.8	Very low	28.7	Very low	150 Å²	150	143.5 Å²	143.5	80%	0.802	74%	0.744	S	S	*	*			cis	178.5	146.4	-24	-169.2	8.2	0	0	0	104.5
363	S	28	Very low	28.9	Very low	93 Å²	93	143.1 Å²	143.1	65%	0.65	75%	0.746	S	S	*	*			trans	163.6	111	151.2	179	0	0	0	0	113.9
364	F	28.4	Very low	29.2	Very low	199 Å²	199	146.5 Å²	146.5	87%	0.873	76%	0.759	S	S	*	*			trans	37.1	126.9	141.2	-65	-95.7	0	0	0	119.2
365	G	25.6	Very low	28.9	Very low	73 Å²	73	146.4 Å²	146.4	75%	0.753	76%	0.758	S	S	*	*			cis	129.6	112.5	15	0	0	0	0	0	109.8
366	E	27	Very low	29.3	Very low	196 Å²	196	143 Å²	143	92%	0.916	75%	0.753	S	S	*	*			trans	-159.2	145.8	151.6	-95.3	-143.1	116.8	0	0	111.7
367	P	35.1	Very low	30.1	Very low	113 Å²	113	144.7 Å²	144.7	73%	0.734	76%	0.764	S	S	*	*			trans	-110.1	145.1	-175.1	38	-26.9	0	0	0	114
368	S	26.5	Very low	30.6	Very low	95 Å²	95	142.7 Å²	142.7	66%	0.664	76%	0.763	S	S	*	*			trans	-163.5	125.5	156.4	-1	0	0	0	0	113.4
369	Y	30.7	Very low	30.9	Very low	208 Å²	208	138.8 Å²	138.8	82%	0.816	76%	0.763	S	S	*	*			trans	-3	157.7	163.7	37.2	-98.1	0	0	0	123.6
370	P	31.6	Very low	31.3	Very low	120 Å²	120	141.6 Å²	141.6	78%	0.779	77%	0.766	S	S	*	*	P	Polyproline II helix	trans	-82.3	126.7	-169.1	33.1	-32	0	0	0	112.9
371	E	30.6	Very low	31.9	Very low	200 Å²	200	143.9 Å²	143.9	94%	0.935	78%	0.779	S	S	*	*	P	Polyproline II helix	trans	-79.8	132.5	165.7	-101.6	179	138.3	0	0	110.9
372	V	32.2	Very low	32.2	Very low	127 Å²	127	135.4 Å²	135.4	77%	0.77	76%	0.756	S	S	*	*	P	Polyproline II helix	trans	-69.2	135.2	-175.7	171.1	0	0	0	0	110	E374	V372-E374 PolarHBondContact O-N 3.01Å; V372-E374 VanDerWaalsContact O-N 3.12Å
373	F	29.3	Very low	32.8	Very low	192 Å²	192	135 Å²	135	84%	0.842	75%	0.749	S	S	*	*			trans	-70.2	99	172	-166.3	-91.8	0	0	0	109.5
374	E	32.1	Very low	33.3	Very low	170 Å²	170	138.2 Å²	138.2	79%	0.794	75%	0.754	S	S	*	*			trans	-84.7	130.2	164.9	-77.1	-174	142.3	0	0	109.8	V372	V372-E374 PolarHBondContact O-N 3.01Å; V372-E374 VanDerWaalsContact O-N 3.12Å
375	P	35.8	Very low	33.8	Very low	96 Å²	96	132.3 Å²	132.3	62%	0.623	73%	0.731	S	S	*	*			trans	-72	146	171.5	30	-31.3	0	0	0	110	L377	P375-L377 PolarHBondContact O-N 3.12Å; P375-L377 VanDerWaalsContact O-N 3.12Å
376	P	33.7	Very low	34.6	Very low	117 Å²	117	134.8 Å²	134.8	76%	0.76	72%	0.723	S	S	*	*			trans	-69	114.5	176.2	-1.9	15.4	0	0	0	109.8	T378	P376-T378 PolarHBondContact O-N 3.26Å
377	L	43.7	Very low	35.2	Very low	176 Å²	176	132.3 Å²	132.3	92%	0.921	71%	0.712	S	S	*	*			trans	-72.9	93.4	158.8	-81.8	167.6	0	0	0	108.3	P375	P375-L377 PolarHBondContact O-N 3.12Å; P375-L377 VanDerWaalsContact O-N 3.12Å
378	T	37.8	Very low	35.5	Very low	122 Å²	122	133.4 Å²	133.4	75%	0.748	71%	0.707	S	S	*	*			trans	-123.8	93.5	163.5	29.3	0	0	0	0	108.9	P376	P376-T378 PolarHBondContact O-N 3.26Å
379	G	32.2	Very low	36.2	Very low	71 Å²	71	132.3 Å²	132.3	73%	0.732	69%	0.691	S	S	*	*			trans	-146.4	75.1	163.4	0	0	0	0	0	106.5	P381	G379-P381 WeakPolarHBondContact O-CD 3.29Å
380	Y	34.3	Very low	36.9	Very low	185 Å²	185	128.1 Å²	128.1	73%	0.725	68%	0.679	S	S	*	*			trans	-71.1	124.6	167.9	-85.6	-87.4	0	0	0	107.3	G382	Y380-G382 PolarHBondContact O-N 2.88Å
381	P	39.4	Very low	37.9	Very low	108 Å²	108	132.1 Å²	132.1	70%	0.701	68%	0.678	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.4	21.5	174	30.8	-33.6	0	0	0	112.7	G379	G379-P381 WeakPolarHBondContact O-CD 3.29Å
382	G	36.6	Very low	39.1	Very low	32 Å²	32	123.2 Å²	123.2	33%	0.33	64%	0.641	S	S	.	*	T	Hydrogen-bonded Turn	trans	-88.7	-29	177.3	0	0	0	0	0	113.2	Y380 L385 E386	Y380-G382 PolarHBondContact O-N 2.88Å; G382-L385 PolarHBondContact O-N 3.46Å; G382-E386 WeakPolarHBondContact O-CG 3.14Å; G382-E386 PolarHBondContact O-N 3.48Å; G382-E386 VanDerWaalsContact O-N 3.1Å
383	E	38.5	Very low	40.8	Very low	142 Å²	142	119.7 Å²	119.7	66%	0.664	62%	0.619	S	S	*	*	H	α-helix	trans	-72	-35.8	-174.7	-66.6	-175.9	154.4	0	0	112.3	L385 E386 E387	E383-L385 VanDerWaalsContact C-N 3.33Å; E383-L385 PolarHBondContact O-N 3.47Å; E383-E386 PolarHBondContact O-N 3.32Å; E383-E387 WeakPolarHBondContact O-CG 3.42Å; E383-E387 PolarHBondContact O-N 3.13Å
384	E	38.1	Very low	42.9	Very low	160 Å²	160	116.7 Å²	116.7	75%	0.748	61%	0.606	S	S	*	*	H	α-helix	trans	-72.7	-24.7	177	-64.1	-175	168.9	0	0	113.1
385	L	39.4	Very low	45.1	Very low	76 Å²	76	109.3 Å²	109.3	40%	0.398	57%	0.572	S	S	.	*	H	α-helix	trans	-83.8	-30.3	176.3	-76.9	167.2	0	0	0	112.3	G382 E383 E388 E389	G382-L385 PolarHBondContact O-N 3.46Å; E383-L385 VanDerWaalsContact C-N 3.33Å; E383-L385 PolarHBondContact O-N 3.47Å; L385-E388 PolarHBondContact O-N 3.13Å; L385-E389 PolarHBondContact O-N 2.85Å
386	E	41.4	Very low	47.3	Very low	125 Å²	125	106.1 Å²	106.1	58%	0.584	56%	0.557	S	S	*	*	H	α-helix	trans	-69.6	-33.2	171.6	-74.5	179.9	-179.6	0	0	111.6	G382 E383 E388 E389 E390	G382-E386 WeakPolarHBondContact O-CG 3.14Å; G382-E386 PolarHBondContact O-N 3.48Å; G382-E386 VanDerWaalsContact O-N 3.1Å; E383-E386 PolarHBondContact O-N 3.32Å; E386-E388 PolarHBondContact O-N 2.78Å; E386-E389 WeakPolarHBondContact O-CA 3.36Å; E386-E389 VanDerWaalsContact O-CB 3.31Å; E386-E389 WeakPolarHBondContact O-CB 3.46Å; E386-E389 PolarHBondContact O-N 3.31Å; E386-E389 VanDerWaalsContact O-N 3.1Å; E386-E390 PolarHBondContact O-N 2.9Å
387	E	40.1	Very low	49.7	Very low	144 Å²	144	101.2 Å²	101.2	67%	0.673	52%	0.524	S	S	*	.	H	α-helix	trans	-66.1	-32.6	174.1	-75.4	-172.5	176.2	0	0	113.4	E383	E383-E387 WeakPolarHBondContact O-CG 3.42Å; E383-E387 PolarHBondContact O-N 3.13Å
388	E	40.7	Very low	51.7	Low	135 Å²	135	94.1 Å²	94.1	63%	0.631	49%	0.494	S	S	*	.	H	α-helix	trans	-73.3	-30.4	169.5	-77.6	-156.3	145.5	0	0	112.3	L385 E386 E390 R391	L385-E388 PolarHBondContact O-N 3.13Å; E386-E388 PolarHBondContact O-N 2.78Å; E388-E390 PolarHBondContact O-N 3.12Å; E388-R391 PolarHBondContact O-N 2.94Å; E388-R391 VanDerWaalsContact O-N 3.16Å
389	E	41.1	Very low	54.1	Low	72 Å²	72	89.3 Å²	89.3	34%	0.336	46%	0.463	S	S	.	.	H	α-helix	trans	-63.2	-25.5	174.7	-161.3	173.3	-178.4	0	0	112.2	Y116 K119 L385 E386	Y116-E389 HydrophobicContact CE1-CG 4.47Å; K119-E389 IonicContact NZ-OE1 3.55Å; K119-E389 PolarHBondContact NZ-OE1 3.48Å; L385-E389 PolarHBondContact O-N 2.85Å; E386-E389 WeakPolarHBondContact O-CA 3.36Å; E386-E389 VanDerWaalsContact O-CB 3.31Å; E386-E389 WeakPolarHBondContact O-CB 3.46Å; E386-E389 PolarHBondContact O-N 3.31Å; E386-E389 VanDerWaalsContact O-N 3.1Å
390	E	46.8	Very low	56.9	Low	120 Å²	120	86 Å²	86	56%	0.561	43%	0.429	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.8	-11.5	176.6	-69.4	-165	158.6	0	0	114.9	A330 E386 E388 G392	A330-E390 WeakPolarHBondContact CB-O 3.46Å; E386-E390 PolarHBondContact O-N 2.9Å; E388-E390 PolarHBondContact O-N 3.12Å; E390-G392 PolarHBondContact O-N 3.37Å
391	R	51.1	Low	59.8	Low	204 Å²	204	78.3 Å²	78.3	77%	0.77	40%	0.4	S	S	*	.			trans	-77.9	69	175.3	-89.7	-175.6	172.6	177.2	1.8	111.4	E388	E388-R391 PolarHBondContact O-N 2.94Å; E388-R391 VanDerWaalsContact O-N 3.16Å
392	G	56.8	Low	62.4	Low	14 Å²	14	74.6 Å²	74.6	14%	0.144	37%	0.373	C	S	.	.	P	Polyproline II helix	trans	-57.2	140.9	173.8	0	0	0	0	0	113.5	A330 E390 K394	A330-G392 VanDerWaalsContact CB-N 3.34Å; E390-G392 PolarHBondContact O-N 3.37Å; G392-K394 PolarHBondContact O-N 3.35Å
393	V	66.9	Low	65.2	Low	52 Å²	52	73.1 Å²	73.1	32%	0.315	36%	0.357	S	S	.	.	P	Polyproline II helix	trans	-67.1	124.9	171.6	-176.1	0	0	0	0	108.8	H120 L124 S329	H120-V393 HydrophobicContact CB-CG2 4.11Å; L124-V393 HydrophobicContact CD1-CB 3.91Å; L124-V393 HydrophobicContact CD1-CG1 3.48Å; L124-V393 VanDerWaalsContact CD1-CG1 3.48Å; L124-V393 HydrophobicContact CD2-CB 4.28Å; L124-V393 HydrophobicContact CD2-CG1 4.23Å; L124-V393 HydrophobicContact CG-CB 4.32Å; L124-V393 HydrophobicContact CG-CG1 4.3Å; S329-V393 PolarHBondContact OG-N 2.92Å; S329-V393 PolarHBondContact OG-O 3.32Å
394	K	75.3	Confident	67.9	Low	129 Å²	129	66.4 Å²	66.4	56%	0.561	33%	0.326	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-96.3	132.1	176.5	-70.1	177.4	-175.7	176.3	0	109	I326 Y327 G392	I326-K394 HydrophobicContact CG2-CB 3.69Å; I326-K394 HydrophobicContact CG2-CD 4.2Å; I326-K394 HydrophobicContact CG2-CG 4.08Å; Y327-K394 WeakPolarHBondContact O-CA 3.22Å; G392-K394 PolarHBondContact O-N 3.35Å
395	L	78.3	Confident	70.7	Confident	15 Å²	15	58.9 Å²	58.9	8%	0.079	29%	0.291	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.3	141.8	177.4	-166.3	66.5	0	0	0	109.7	L124 V128 Y327 D399 F400 A448	L124-L395 HydrophobicContact CD2-CB 4.13Å; V128-L395 HydrophobicContact CG2-CD2 4.04Å; Y327-L395 WeakPolarHBondContact CB-O 3.44Å; Y327-L395 PolarHBondContact N-O 3.03Å; Y327-L395 PolarHBondContact O-N 3.46Å; L395-D399 HydrophobicContact CD1-CB 4.47Å; L395-D399 WeakPolarHBondContact CD1-OD2 3.22Å; L395-D399 HydrophobicContact CD2-CB 4.44Å; L395-D399 HydrophobicContact CG-CB 4.25Å; L395-F400 HydrophobicContact CB-CE2 4.05Å; L395-F400 HydrophobicContact CD2-CD2 4.23Å; L395-F400 HydrophobicContact CD2-CE2 3.59Å; L395-F400 HydrophobicContact CD2-CZ 4.11Å; L395-F400 HydrophobicContact CG-CE2 3.98Å; L395-A448 HydrophobicContact CD1-CB 4.27Å
396	G	81.4	Confident	73.3	Confident	30 Å²	30	55.3 Å²	55.3	31%	0.309	27%	0.272	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-69.4	137.5	178.5	0	0	0	0	0	110.5	G398 D399 F400	G396-G398 PolarHBondContact O-N 2.95Å; G396-D399 WeakPolarHBondContact O-CB 3.39Å; G396-D399 PolarHBondContact O-N 3.5Å; G396-D399 VanDerWaalsContact O-N 3.08Å; G396-F400 WeakPolarHBondContact O-CD2 3.37Å
397	L	83.1	Confident	75.9	Confident	13 Å²	13	49.4 Å²	49.4	7%	0.068	25%	0.245	C	C	.	.	H	α-helix	trans	-62	-24.6	174.6	-67.4	171.3	0	0	0	112.6	L265 A324 L325 D399 F400 I401	L265-L397 HydrophobicContact CB-CD2 3.96Å; L265-L397 HydrophobicContact CD1-CD2 4.49Å; L265-L397 HydrophobicContact CD2-CD1 3.72Å; L265-L397 HydrophobicContact CD2-CD2 4Å; L265-L397 HydrophobicContact CD2-CG 4.48Å; L265-L397 HydrophobicContact CG-CD2 4.37Å; A324-L397 WeakPolarHBondContact O-CD1 3.26Å; L325-L397 WeakPolarHBondContact O-CG 3.28Å; L325-L397 PolarHBondContact O-N 3.39Å; L397-D399 VanDerWaalsContact C-N 3.25Å; L397-D399 PolarHBondContact O-N 2.87Å; L397-F400 PolarHBondContact O-N 3.48Å; L397-I401 WeakPolarHBondContact O-CG1 3.45Å; L397-I401 PolarHBondContact O-N 3.17Å
398	G	85.4	Confident	78.4	Confident	28 Å²	28	42.5 Å²	42.5	29%	0.289	21%	0.213	S	C	.	.	H	α-helix	trans	-55.1	-41.5	172.6	0	0	0	0	0	112.3	G396 F400 I401 F402	G396-G398 PolarHBondContact O-N 2.95Å; G398-F400 PolarHBondContact O-N 3.4Å; G398-I401 WeakPolarHBondContact O-CB 3.37Å; G398-I401 PolarHBondContact O-N 2.86Å; G398-I401 VanDerWaalsContact O-N 3.13Å; G398-F402 WeakPolarHBondContact O-CD2 3.48Å; G398-F402 PolarHBondContact O-N 3.48Å
399	D	88.8	Confident	80.9	Confident	21 Å²	21	36.9 Å²	36.9	11%	0.112	19%	0.186	C	C	.	.	H	α-helix	trans	-61.9	-46.3	-178	-58.5	-17.1	0	0	0	110.6	L395 G396 L397 I401 F402 Y403	L395-D399 HydrophobicContact CD1-CB 4.47Å; L395-D399 WeakPolarHBondContact CD1-OD2 3.22Å; L395-D399 HydrophobicContact CD2-CB 4.44Å; L395-D399 HydrophobicContact CG-CB 4.25Å; G396-D399 WeakPolarHBondContact O-CB 3.39Å; G396-D399 PolarHBondContact O-N 3.5Å; G396-D399 VanDerWaalsContact O-N 3.08Å; L397-D399 VanDerWaalsContact C-N 3.25Å; L397-D399 PolarHBondContact O-N 2.87Å; D399-I401 VanDerWaalsContact C-N 3.29Å; D399-I401 PolarHBondContact O-N 3Å; D399-F402 PolarHBondContact O-N 3.03Å; D399-Y403 HydrophobicContact CB-CD2 4.37Å; D399-Y403 HydrophobicContact CB-CE2 3.71Å; D399-Y403 WeakPolarHBondContact O-CB 3.38Å; D399-Y403 WeakPolarHBondContact O-CD2 3.35Å; D399-Y403 PolarHBondContact O-N 2.85Å
400	F	91.8	Very high	83.3	Confident	1 Å²	1	33.7 Å²	33.7	0%	0.004	17%	0.172	C	C	.	.	H	α-helix	trans	-56.8	-43.9	175	-70	-107.2	0	0	0	112	P127 V128 C131 Y327 L395 G396 L397 G398 S404	P127-F400 HydrophobicContact CB-CE1 3.89Å; P127-F400 HydrophobicContact CB-CZ 4.37Å; P127-F400 HydrophobicContact CG-CE1 4.18Å; P127-F400 HydrophobicContact CG-CZ 4.28Å; V128-F400 HydrophobicContact CB-CE1 4.27Å; V128-F400 HydrophobicContact CG2-CD1 3.85Å; V128-F400 HydrophobicContact CG2-CE1 3.45Å; V128-F400 VanDerWaalsContact CG2-CE1 3.45Å; V128-F400 HydrophobicContact CG2-CE2 4.22Å; V128-F400 HydrophobicContact CG2-CG 4.38Å; V128-F400 HydrophobicContact CG2-CZ 3.66Å; C131-F400 HydrophobicContact CB-CD1 4.19Å; Y327-F400 HydrophobicContact CD1-CE2 4.37Å; Y327-F400 AromaticContact CD1-CZ 3.89Å; Y327-F400 HydrophobicContact CD1-CZ 3.89Å; Y327-F400 HydrophobicContact CD2-CZ 4.04Å; Y327-F400 HydrophobicContact CE1-CZ 4.39Å; Y327-F400 AromaticContact CG-CE2 4Å; Y327-F400 HydrophobicContact CG-CE2 4Å; Y327-F400 AromaticContact CG-CZ 3.71Å; Y327-F400 HydrophobicContact CG-CZ 3.71Å; L395-F400 HydrophobicContact CB-CE2 4.05Å; L395-F400 HydrophobicContact CD2-CD2 4.23Å; L395-F400 HydrophobicContact CD2-CE2 3.59Å; L395-F400 HydrophobicContact CD2-CZ 4.11Å; L395-F400 HydrophobicContact CG-CE2 3.98Å; G396-F400 WeakPolarHBondContact O-CD2 3.37Å; L397-F400 PolarHBondContact O-N 3.48Å; G398-F400 PolarHBondContact O-N 3.4Å; F400-S404 WeakPolarHBondContact O-CB 3.29Å; F400-S404 PolarHBondContact O-N 2.96Å; F400-S404 PolarHBondContact O-OG 2.93Å
401	I	94	Very high	85.5	Confident	24 Å²	24	28.1 Å²	28.1	12%	0.123	15%	0.147	C	C	.	.	H	α-helix	trans	-63.9	-50.3	-179.4	-64	164.4	0	0	0	109.4	M272 A273 F276 L397 G398 D399 S404 V405	M272-I401 HydrophobicContact CB-CD1 3.9Å; M272-I401 HydrophobicContact CB-CG1 4.02Å; M272-I401 HydrophobicContact CB-CG2 4.25Å; M272-I401 HydrophobicContact CG-CD1 4.35Å; A273-I401 HydrophobicContact CB-CG2 4.43Å; F276-I401 HydrophobicContact CD2-CG2 3.73Å; F276-I401 HydrophobicContact CE2-CG2 3.87Å; L397-I401 WeakPolarHBondContact O-CG1 3.45Å; L397-I401 PolarHBondContact O-N 3.17Å; G398-I401 WeakPolarHBondContact O-CB 3.37Å; G398-I401 PolarHBondContact O-N 2.86Å; G398-I401 VanDerWaalsContact O-N 3.13Å; D399-I401 VanDerWaalsContact C-N 3.29Å; D399-I401 PolarHBondContact O-N 3Å; I401-S404 PolarHBondContact O-N 3.09Å; I401-V405 HydrophobicContact CG2-CG2 4.27Å; I401-V405 VanDerWaalsContact O-CG2 3.26Å; I401-V405 WeakPolarHBondContact O-CG2 3.34Å; I401-V405 PolarHBondContact O-N 2.99Å
402	F	94.6	Very high	87.2	Confident	30 Å²	30	19.7 Å²	19.7	13%	0.132	12%	0.12	C	C	.	.	H	α-helix	trans	-70.6	-36.7	-175.6	-66.3	-61.4	0	0	0	113.3	L289 I292 G398 D399 S404 V405 L406 L449 I453	L289-F402 HydrophobicContact CD2-CB 4.33Å; L289-F402 HydrophobicContact CD2-CD1 4Å; I292-F402 HydrophobicContact CD1-CD1 4.43Å; I292-F402 HydrophobicContact CD1-CE1 3.45Å; I292-F402 VanDerWaalsContact CD1-CE1 3.45Å; I292-F402 HydrophobicContact CD1-CZ 3.59Å; I292-F402 HydrophobicContact CG2-CD2 4.33Å; I292-F402 HydrophobicContact CG2-CE1 4.19Å; I292-F402 HydrophobicContact CG2-CE2 3.87Å; I292-F402 HydrophobicContact CG2-CZ 3.8Å; G398-F402 WeakPolarHBondContact O-CD2 3.48Å; G398-F402 PolarHBondContact O-N 3.48Å; D399-F402 PolarHBondContact O-N 3.03Å; F402-S404 VanDerWaalsContact C-N 3.3Å; F402-S404 PolarHBondContact O-N 3.1Å; F402-V405 PolarHBondContact O-N 3.03Å; F402-L406 PolarHBondContact O-N 3.32Å; F402-L449 HydrophobicContact CB-CD1 4.4Å; F402-L449 HydrophobicContact CD2-CD1 3.47Å; F402-L449 VanDerWaalsContact CD2-CD1 3.47Å; F402-L449 HydrophobicContact CE2-CD1 4.12Å; F402-L449 HydrophobicContact CG-CD1 4.23Å; F402-I453 HydrophobicContact CB-CD1 4.18Å
403	Y	95.3	Very high	88.3	Confident	0 Å²	0	20.6 Å²	20.6	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-59	-45.5	170.5	-60.6	-27.2	0	0	0	111	V128 D399 L406 V407 I428 L432 A448 I453	V128-Y403 HydrophobicContact CG1-CD2 3.82Å; V128-Y403 HydrophobicContact CG1-CE2 4.48Å; D399-Y403 HydrophobicContact CB-CD2 4.37Å; D399-Y403 HydrophobicContact CB-CE2 3.71Å; D399-Y403 WeakPolarHBondContact O-CB 3.38Å; D399-Y403 WeakPolarHBondContact O-CD2 3.35Å; D399-Y403 PolarHBondContact O-N 2.85Å; Y403-L406 PolarHBondContact O-N 2.91Å; Y403-V407 WeakPolarHBondContact O-CG1 3.32Å; Y403-V407 PolarHBondContact O-N 3.2Å; Y403-V407 VanDerWaalsContact O-N 3.12Å; Y403-I428 HydrophobicContact CD1-CG2 3.77Å; Y403-I428 HydrophobicContact CD2-CG2 4.23Å; Y403-I428 HydrophobicContact CE1-CG2 4.31Å; Y403-I428 HydrophobicContact CG-CG2 3.74Å; Y403-L432 HydrophobicContact CE2-CD1 4.02Å; Y403-A448 PolarHBondContact OH-O 3.46Å; Y403-I453 HydrophobicContact CD1-CD1 3.95Å; Y403-I453 HydrophobicContact CD1-CG1 4.49Å; Y403-I453 HydrophobicContact CE1-CD1 4.33Å; Y403-I453 HydrophobicContact CE1-CG1 4.37Å
404	S	96.1	Very high	87.8	Confident	1 Å²	1	22.1 Å²	22.1	1%	0.007	15%	0.15	C	C	.	.	H	α-helix	trans	-67.7	-35.6	178.7	-60.5	0	0	0	0	113.1	C131 A273 F400 I401 F402 V407 G408	C131-S404 PolarHBondContact SG-OG 3.35Å; A273-S404 VanDerWaalsContact CB-CB 3.5Å; F400-S404 WeakPolarHBondContact O-CB 3.29Å; F400-S404 PolarHBondContact O-N 2.96Å; F400-S404 PolarHBondContact O-OG 2.93Å; I401-S404 PolarHBondContact O-N 3.09Å; F402-S404 VanDerWaalsContact C-N 3.3Å; F402-S404 PolarHBondContact O-N 3.1Å; S404-V407 WeakPolarHBondContact O-CG1 3.5Å; S404-G408 WeakPolarHBondContact O-CA 3.48Å; S404-G408 PolarHBondContact O-N 3.16Å
405	V	95.5	Very high	86.8	Confident	3 Å²	3	17.9 Å²	17.9	2%	0.018	14%	0.136	C	C	.	.	H	α-helix	trans	-65.8	-44.2	174.6	171.2	0	0	0	0	110.8	A273 F276 L289 I401 F402 K409	A273-V405 HydrophobicContact CB-CG2 3.84Å; F276-V405 HydrophobicContact CB-CG1 4.47Å; F276-V405 HydrophobicContact CB-CG2 3.59Å; F276-V405 HydrophobicContact CD2-CG2 4.18Å; F276-V405 HydrophobicContact CG-CG2 4.22Å; L289-V405 HydrophobicContact CD1-CG1 4.35Å; L289-V405 HydrophobicContact CD2-CB 4.36Å; L289-V405 HydrophobicContact CD2-CG1 4.07Å; L289-V405 HydrophobicContact CG-CG1 4.47Å; I401-V405 HydrophobicContact CG2-CG2 4.27Å; I401-V405 VanDerWaalsContact O-CG2 3.26Å; I401-V405 WeakPolarHBondContact O-CG2 3.34Å; I401-V405 PolarHBondContact O-N 2.99Å; F402-V405 PolarHBondContact O-N 3.03Å; V405-K409 HydrophobicContact CG1-CG 4.31Å; V405-K409 VanDerWaalsContact O-CB 3.29Å; V405-K409 WeakPolarHBondContact O-CB 3.48Å; V405-K409 VanDerWaalsContact O-CG 3.31Å; V405-K409 WeakPolarHBondContact O-CG 3.31Å; V405-K409 PolarHBondContact O-N 3.24Å
406	L	94.9	Very high	85.8	Confident	0 Å²	0	18.7 Å²	18.7	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-60.9	-54.4	179.6	-168.7	158.3	0	0	0	110.9	W286 L289 F402 Y403 G408 K409 A410 C424 I428 I453 L457	W286-L406 HydrophobicContact CZ3-CG 4.28Å; L289-L406 HydrophobicContact CD1-CB 4Å; L289-L406 HydrophobicContact CD1-CG 4.22Å; F402-L406 PolarHBondContact O-N 3.32Å; Y403-L406 PolarHBondContact O-N 2.91Å; L406-G408 PolarHBondContact O-N 3.36Å; L406-K409 PolarHBondContact O-N 3.47Å; L406-A410 PolarHBondContact O-N 3.29Å; L406-C424 HydrophobicContact CD2-CB 3.79Å; L406-I428 HydrophobicContact CB-CD1 4.4Å; L406-I428 HydrophobicContact CD2-CD1 4.12Å; L406-I453 HydrophobicContact CB-CD1 4.43Å; L406-I453 HydrophobicContact CD1-CD1 3.8Å; L406-I453 HydrophobicContact CD1-CG2 4.32Å; L406-L457 HydrophobicContact CD1-CD2 4.35Å; L406-L457 HydrophobicContact CD1-CG 4.26Å
407	V	95.2	Very high	85.5	Confident	1 Å²	1	19 Å²	19	1%	0.006	14%	0.143	C	C	.	.	H	α-helix	trans	-67.4	-36.8	-179.4	71.8	0	0	0	0	112.1	M132 V136 Y403 S404 A410 A411 T421 F425 I428	M132-V407 HydrophobicContact CB-CG1 3.98Å; M132-V407 HydrophobicContact CG-CG1 3.87Å; M132-V407 HydrophobicContact SD-CG1 4.23Å; V136-V407 HydrophobicContact CG2-CB 4.42Å; V136-V407 HydrophobicContact CG2-CG1 3.99Å; V136-V407 HydrophobicContact CG2-CG2 3.7Å; Y403-V407 WeakPolarHBondContact O-CG1 3.32Å; Y403-V407 PolarHBondContact O-N 3.2Å; Y403-V407 VanDerWaalsContact O-N 3.12Å; S404-V407 WeakPolarHBondContact O-CG1 3.5Å; V407-A410 WeakPolarHBondContact O-CB 3.33Å; V407-A410 PolarHBondContact O-N 2.92Å; V407-A411 WeakPolarHBondContact O-CB 3.48Å; V407-A411 PolarHBondContact O-N 3.08Å; V407-T421 HydrophobicContact CG2-CG2 3.71Å; V407-F425 HydrophobicContact CG2-CB 4.3Å; V407-I428 HydrophobicContact CB-CD1 4.47Å
408	G	94.1	Very high	85.8	Confident	0 Å²	0	26.1 Å²	26.1	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-69.2	-36.2	178.1	0	0	0	0	0	112.9	S404 L406 A411 A412	S404-G408 WeakPolarHBondContact O-CA 3.48Å; S404-G408 PolarHBondContact O-N 3.16Å; L406-G408 PolarHBondContact O-N 3.36Å; G408-A411 PolarHBondContact O-N 2.97Å; G408-A412 WeakPolarHBondContact O-CB 3.49Å; G408-A412 PolarHBondContact O-N 3.14Å
409	K	92.2	Very high	86	Confident	16 Å²	16	28.4 Å²	28.4	7%	0.07	17%	0.174	C	C	.	.	H	α-helix	trans	-66.1	-42.4	170.5	-78.1	-61.5	-163.8	-176.1	0	111.5	I277 L280 A285 W286 V405 L406 A411 A412 T413	I277-K409 HydrophobicContact CG1-CD 4.35Å; I277-K409 HydrophobicContact CG1-CG 4.27Å; I277-K409 HydrophobicContact CG2-CD 4.14Å; I277-K409 PolarHBondContact O-NZ 3.04Å; L280-K409 PolarHBondContact O-NZ 2.9Å; A285-K409 HydrophobicContact CB-CD 4.35Å; A285-K409 HydrophobicContact CB-CG 4.34Å; W286-K409 HydrophobicContact CH2-CB 3.96Å; W286-K409 HydrophobicContact CZ2-CB 3.94Å; V405-K409 HydrophobicContact CG1-CG 4.31Å; V405-K409 VanDerWaalsContact O-CB 3.29Å; V405-K409 WeakPolarHBondContact O-CB 3.48Å; V405-K409 VanDerWaalsContact O-CG 3.31Å; V405-K409 WeakPolarHBondContact O-CG 3.31Å; V405-K409 PolarHBondContact O-N 3.24Å; L406-K409 PolarHBondContact O-N 3.47Å; K409-A411 PolarHBondContact O-N 2.94Å; K409-A412 PolarHBondContact O-N 3.5Å; K409-A412 VanDerWaalsContact O-N 3.1Å; K409-T413 PolarHBondContact O-N 2.99Å; K409-T413 VanDerWaalsContact O-N 3.09Å; K409-T413 PolarHBondContact O-OG1 3.36Å
410	A	91.9	Very high	86.1	Confident	5 Å²	5	27.6 Å²	27.6	4%	0.041	17%	0.17	C	C	.	.	H	α-helix	trans	-58.7	-38.4	173.6	0	0	0	0	0	112.2	L406 V407 T420 C424 Y460	L406-A410 PolarHBondContact O-N 3.29Å; V407-A410 WeakPolarHBondContact O-CB 3.33Å; V407-A410 PolarHBondContact O-N 2.92Å; A410-T420 HydrophobicContact CB-CG2 4.49Å; A410-C424 HydrophobicContact CB-CB 4.43Å; A410-Y460 HydrophobicContact CB-CD2 3.7Å; A410-Y460 HydrophobicContact CB-CE2 3.85Å
411	A	91.6	Very high	86.2	Confident	4 Å²	4	27.8 Å²	27.8	3%	0.033	17%	0.172	C	C	.	.	H	α-helix	trans	-70.9	-27.2	176.1	0	0	0	0	0	114.1	V136 I139 K140 V407 G408 K409 T421	V136-A411 HydrophobicContact CG1-CB 4.23Å; V136-A411 HydrophobicContact CG2-CB 4.41Å; I139-A411 HydrophobicContact CG2-CB 4.01Å; K140-A411 PolarHBondContact NZ-O 3.05Å; V407-A411 WeakPolarHBondContact O-CB 3.48Å; V407-A411 PolarHBondContact O-N 3.08Å; G408-A411 PolarHBondContact O-N 2.97Å; K409-A411 PolarHBondContact O-N 2.94Å; A411-T421 WeakPolarHBondContact CA-OG1 3.4Å; A411-T421 HydrophobicContact CB-CG2 4Å
412	A	88.5	Confident	86.2	Confident	26 Å²	26	32 Å²	32	22%	0.215	19%	0.193	C	C	.	.	H	α-helix	trans	-87.2	-28.8	-175.4	0	0	0	0	0	114.2	I139 T146 G408 K409 G414	I139-A412 HydrophobicContact CG2-CB 3.72Å; T146-A412 HydrophobicContact CG2-CB 3.98Å; G408-A412 WeakPolarHBondContact O-CB 3.49Å; G408-A412 PolarHBondContact O-N 3.14Å; K409-A412 PolarHBondContact O-N 3.5Å; K409-A412 VanDerWaalsContact O-N 3.1Å; A412-G414 PolarHBondContact O-N 2.69Å
413	T	78.3	Confident	86.1	Confident	33 Å²	33	31.5 Å²	31.5	20%	0.202	20%	0.195	C	C	.	.	S	Bend	trans	-60.9	136	-178.5	-56.8	0	0	0	0	110.7	K409 S415 G416 Y460	K409-T413 PolarHBondContact O-N 2.99Å; K409-T413 VanDerWaalsContact O-N 3.09Å; K409-T413 PolarHBondContact O-OG1 3.36Å; T413-S415 PolarHBondContact O-N 3.32Å; T413-G416 PolarHBondContact O-N 2.9Å; T413-G416 VanDerWaalsContact O-N 3.1Å; T413-Y460 PolarHBondContact OG1-OH 3.27Å
414	G	56.4	Low	86	Confident	85 Å²	85	31.5 Å²	31.5	88%	0.876	20%	0.195	S	C	*	.	T	Hydrogen-bonded Turn	trans	-60.7	12.3	-154.8	0	0	0	0	0	120	A412	A412-G414 PolarHBondContact O-N 2.69Å
415	S	54.6	Low	86	Confident	40 Å²	40	33.7 Å²	33.7	28%	0.28	21%	0.205	S	C	.	.	T	Hydrogen-bonded Turn	trans	-99.4	-16.2	166.1	67.7	0	0	0	0	115	T413 D417 R468	T413-S415 PolarHBondContact O-N 3.32Å; S415-D417 WeakPolarHBondContact CB-OD2 3.41Å; S415-D417 PolarHBondContact O-N 3.29Å; S415-D417 VanDerWaalsContact O-N 3.13Å; S415-D417 PolarHBondContact OG-OD2 3.16Å; S415-R468 PolarHBondContact OG-NH1 2.95Å; S415-R468 PolarHBondContact OG-NH2 3.26Å
416	G	58.6	Low	86	Confident	31 Å²	31	36.6 Å²	36.6	32%	0.32	22%	0.223	S	C	.	.			trans	64.9	15.1	176.2	0	0	0	0	0	114.7	K140 T413 W418	K140-G416 VanDerWaalsContact NZ-C 3.27Å; K140-G416 VanDerWaalsContact NZ-CA 3.31Å; K140-G416 PolarHBondContact NZ-O 2.83Å; T413-G416 PolarHBondContact O-N 2.9Å; T413-G416 VanDerWaalsContact O-N 3.1Å; G416-W418 PolarHBondContact O-N 2.87Å
417	D	75.5	Confident	86	Confident	37 Å²	37	36.7 Å²	36.7	20%	0.198	22%	0.223	C	C	.	.			trans	-69.9	127.6	-174.2	-59.5	-52.4	0	0	0	112.3	S415 N419 T421 R468	S415-D417 WeakPolarHBondContact CB-OD2 3.41Å; S415-D417 PolarHBondContact O-N 3.29Å; S415-D417 VanDerWaalsContact O-N 3.13Å; S415-D417 PolarHBondContact OG-OD2 3.16Å; D417-N419 PolarHBondContact O-N 2.85Å; D417-T421 PolarHBondContact O-OG1 3.18Å; D417-R468 VanDerWaalsContact OD2-CD 3.24Å; D417-R468 WeakPolarHBondContact OD2-CD 3.31Å; D417-R468 IonicContact OD2-CZ 3.42Å; D417-R468 IonicContact OD2-NE 3.69Å; D417-R468 PolarHBondContact OD2-NE 3.16Å; D417-R468 IonicContact OD2-NH1 2.65Å; D417-R468 IonicContact OD2-NH2 2.76Å; D417-R468 PolarHBondContact OD2-NH2 2.82Å
418	W	87.9	Confident	86	Confident	162 Å²	162	36.6 Å²	36.6	61%	0.614	22%	0.223	S	C	*	.	H	α-helix	trans	-64.6	-27.5	173.2	-68.4	99.8	0	0	0	111.6	V136 K140 G416 T421 L422	V136-W418 HydrophobicContact CG1-CZ3 4.09Å; K140-W418 HydrophobicContact CD-CZ2 4.46Å; K140-W418 HydrophobicContact CG-CH2 3.98Å; K140-W418 HydrophobicContact CG-CZ2 4.23Å; G416-W418 PolarHBondContact O-N 2.87Å; W418-T421 PolarHBondContact O-N 3.34Å; W418-L422 VanDerWaalsContact O-CB 3.23Å; W418-L422 WeakPolarHBondContact O-CB 3.42Å; W418-L422 PolarHBondContact O-N 3.27Å
419	N	90	Very high	85.9	Confident	76 Å²	76	38 Å²	38	41%	0.406	23%	0.23	S	C	.	.	H	α-helix	trans	-60.1	-51	-178.6	-63.7	-1.5	0	0	0	112	D417 T421 L422 A423	D417-N419 PolarHBondContact O-N 2.85Å; N419-T421 PolarHBondContact O-N 3Å; N419-L422 PolarHBondContact O-N 3.34Å; N419-A423 VanDerWaalsContact O-CB 3.27Å; N419-A423 WeakPolarHBondContact O-CB 3.18Å; N419-A423 PolarHBondContact O-N 3.04Å
420	T	91.4	Very high	85.9	Confident	4 Å²	4	41.6 Å²	41.6	3%	0.025	25%	0.249	C	C	.	.	H	α-helix	trans	-66.5	-39.6	179.5	-48.9	0	0	0	0	111.5	A410 A423 C424 Y460 T463 D464	A410-T420 HydrophobicContact CB-CG2 4.49Å; T420-A423 PolarHBondContact O-N 3.29Å; T420-C424 WeakPolarHBondContact O-CB 3.46Å; T420-C424 PolarHBondContact O-N 2.89Å; T420-C424 PolarHBondContact O-SG 3.32Å; T420-Y460 HydrophobicContact CG2-CD2 3.54Å; T420-Y460 HydrophobicContact CG2-CE2 3.79Å; T420-Y460 HydrophobicContact CG2-CG 4.48Å; T420-T463 HydrophobicContact CG2-CG2 4.44Å; T420-D464 HydrophobicContact CG2-CB 4.46Å
421	T	93.3	Very high	85.9	Confident	6 Å²	6	41.4 Å²	41.4	4%	0.037	25%	0.247	C	C	.	.	H	α-helix	trans	-64.1	-46.2	178.1	-52.1	0	0	0	0	111.1	V136 V407 A411 D417 W418 N419 C424 F425	V136-T421 HydrophobicContact CG1-CG2 4Å; V136-T421 HydrophobicContact CG2-CG2 3.9Å; V407-T421 HydrophobicContact CG2-CG2 3.71Å; A411-T421 WeakPolarHBondContact CA-OG1 3.4Å; A411-T421 HydrophobicContact CB-CG2 4Å; D417-T421 PolarHBondContact O-OG1 3.18Å; W418-T421 PolarHBondContact O-N 3.34Å; N419-T421 PolarHBondContact O-N 3Å; T421-C424 PolarHBondContact O-N 3.44Å; T421-F425 WeakPolarHBondContact O-CB 3.42Å; T421-F425 PolarHBondContact O-N 2.96Å
422	L	93.4	Very high	85.8	Confident	111 Å²	111	41.3 Å²	41.3	58%	0.581	25%	0.246	S	C	*	.	H	α-helix	trans	-66.7	-41.9	179	-174.4	67.5	0	0	0	111.5	W418 N419 C424 F425 V426	W418-L422 VanDerWaalsContact O-CB 3.23Å; W418-L422 WeakPolarHBondContact O-CB 3.42Å; W418-L422 PolarHBondContact O-N 3.27Å; N419-L422 PolarHBondContact O-N 3.34Å; L422-C424 VanDerWaalsContact C-N 3.34Å; L422-C424 PolarHBondContact O-N 3.44Å; L422-F425 WeakPolarHBondContact O-CB 3.46Å; L422-F425 PolarHBondContact O-N 3.37Å; L422-V426 WeakPolarHBondContact O-CG2 3.18Å; L422-V426 PolarHBondContact O-N 3.02Å
423	A	93.8	Very high	85.8	Confident	21 Å²	21	43 Å²	43	17%	0.174	26%	0.256	C	S	.	.	H	α-helix	trans	-59.3	-44.4	174.8	0	0	0	0	0	111.6	N419 T420 A427 F459 T463	N419-A423 VanDerWaalsContact O-CB 3.27Å; N419-A423 WeakPolarHBondContact O-CB 3.18Å; N419-A423 PolarHBondContact O-N 3.04Å; T420-A423 PolarHBondContact O-N 3.29Å; A423-A427 VanDerWaalsContact O-CB 3.23Å; A423-A427 WeakPolarHBondContact O-CB 3.28Å; A423-A427 PolarHBondContact O-N 3.33Å; A423-F459 HydrophobicContact CB-CD1 4.45Å; A423-T463 HydrophobicContact CB-CG2 4.07Å; A423-T463 WeakPolarHBondContact CB-OG1 3.4Å
424	C	93.4	Very high	86.3	Confident	0 Å²	0	44.4 Å²	44.4	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-64.5	-42.7	175.3	-66.7	0	0	0	0	112.3	L406 A410 T420 T421 L422 A427 I428 Y460	L406-C424 HydrophobicContact CD2-CB 3.79Å; A410-C424 HydrophobicContact CB-CB 4.43Å; T420-C424 WeakPolarHBondContact O-CB 3.46Å; T420-C424 PolarHBondContact O-N 2.89Å; T420-C424 PolarHBondContact O-SG 3.32Å; T421-C424 PolarHBondContact O-N 3.44Å; L422-C424 VanDerWaalsContact C-N 3.34Å; L422-C424 PolarHBondContact O-N 3.44Å; C424-A427 PolarHBondContact O-N 2.85Å; C424-I428 VanDerWaalsContact O-CG1 3.31Å; C424-I428 WeakPolarHBondContact O-CG1 3.43Å; C424-I428 PolarHBondContact O-N 3.4Å; C424-Y460 VanDerWaalsContact SG-CB 3.58Å
425	F	95	Very high	87.8	Confident	46 Å²	46	40.5 Å²	40.5	20%	0.202	22%	0.221	C	C	.	.	H	α-helix	trans	-58.9	-51	177.3	177.2	-90.1	0	0	0	111.2	T129 M132 V407 T421 L422 A427 I428 L429	T129-F425 HydrophobicContact CG2-CE2 4.13Å; T129-F425 HydrophobicContact CG2-CZ 3.67Å; M132-F425 HydrophobicContact CB-CD2 4.17Å; M132-F425 HydrophobicContact CB-CE2 4.16Å; M132-F425 HydrophobicContact CE-CD2 3.71Å; M132-F425 HydrophobicContact CE-CE2 3.59Å; M132-F425 HydrophobicContact CE-CZ 4.42Å; M132-F425 HydrophobicContact SD-CD2 4.05Å; M132-F425 HydrophobicContact SD-CE2 4.44Å; V407-F425 HydrophobicContact CG2-CB 4.3Å; T421-F425 WeakPolarHBondContact O-CB 3.42Å; T421-F425 PolarHBondContact O-N 2.96Å; L422-F425 WeakPolarHBondContact O-CB 3.46Å; L422-F425 PolarHBondContact O-N 3.37Å; F425-A427 PolarHBondContact O-N 3.3Å; F425-I428 PolarHBondContact O-N 2.97Å; F425-L429 HydrophobicContact CD1-CD1 3.98Å; F425-L429 HydrophobicContact CE1-CD1 3.43Å; F425-L429 VanDerWaalsContact CE1-CD1 3.43Å; F425-L429 HydrophobicContact CE1-CG 4.34Å; F425-L429 HydrophobicContact CZ-CD1 3.86Å; F425-L429 WeakPolarHBondContact O-CG 3.47Å; F425-L429 PolarHBondContact O-N 3.45Å; F425-L429 VanDerWaalsContact O-N 3.14Å
426	V	95.2	Very high	89.1	Confident	65 Å²	65	40 Å²	40	39%	0.394	22%	0.215	S	C	.	.	H	α-helix	trans	-63.5	-41.4	178	174	0	0	0	0	111	L422 I428 L429 I430	L422-V426 WeakPolarHBondContact O-CG2 3.18Å; L422-V426 PolarHBondContact O-N 3.02Å; V426-I428 PolarHBondContact O-N 2.65Å; V426-L429 PolarHBondContact O-N 3.34Å; V426-I430 HydrophobicContact CG1-CD1 3.64Å; V426-I430 HydrophobicContact CG1-CG1 4.23Å; V426-I430 VanDerWaalsContact O-CG1 3.32Å; V426-I430 WeakPolarHBondContact O-CG1 3.29Å; V426-I430 PolarHBondContact O-N 3.03Å
427	A	95.3	Very high	90.4	Very high	1 Å²	1	43.8 Å²	43.8	1%	0.008	23%	0.227	C	C	.	.	H	α-helix	trans	-61.9	-40.5	178	0	0	0	0	0	112.9	A423 C424 F425 G431 F455 F459	A423-A427 VanDerWaalsContact O-CB 3.23Å; A423-A427 WeakPolarHBondContact O-CB 3.28Å; A423-A427 PolarHBondContact O-N 3.33Å; C424-A427 PolarHBondContact O-N 2.85Å; F425-A427 PolarHBondContact O-N 3.3Å; A427-G431 PolarHBondContact O-N 2.89Å; A427-F455 HydrophobicContact CB-CB 4.42Å; A427-F459 HydrophobicContact CB-CB 3.77Å; A427-F459 HydrophobicContact CB-CD1 4.24Å; A427-F459 HydrophobicContact CB-CD2 3.89Å; A427-F459 HydrophobicContact CB-CG 3.69Å
428	I	94.8	Very high	90.7	Very high	0 Å²	0	44.1 Å²	44.1	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-63.2	-45.5	174.9	-69.7	164.6	0	0	0	110.4	M132 Y403 L406 V407 C424 F425 V426 G431 L432	M132-I428 HydrophobicContact SD-CD1 4.03Å; M132-I428 HydrophobicContact SD-CG2 4.21Å; Y403-I428 HydrophobicContact CD1-CG2 3.77Å; Y403-I428 HydrophobicContact CD2-CG2 4.23Å; Y403-I428 HydrophobicContact CE1-CG2 4.31Å; Y403-I428 HydrophobicContact CG-CG2 3.74Å; L406-I428 HydrophobicContact CB-CD1 4.4Å; L406-I428 HydrophobicContact CD2-CD1 4.12Å; V407-I428 HydrophobicContact CB-CD1 4.47Å; C424-I428 VanDerWaalsContact O-CG1 3.31Å; C424-I428 WeakPolarHBondContact O-CG1 3.43Å; C424-I428 PolarHBondContact O-N 3.4Å; F425-I428 PolarHBondContact O-N 2.97Å; V426-I428 PolarHBondContact O-N 2.65Å; I428-G431 PolarHBondContact O-N 3.26Å; I428-L432 WeakPolarHBondContact O-CB 3.49Å; I428-L432 PolarHBondContact O-N 2.94Å
429	L	92.9	Very high	90.2	Very high	28 Å²	28	38.9 Å²	38.9	15%	0.147	21%	0.212	C	C	.	.	H	α-helix	trans	-63.4	-43.1	179.2	-68.6	-173	0	0	0	112.3	F125 T129 M132 F425 V426 G431 L432 C433	F125-L429 HydrophobicContact CD1-CD2 3.79Å; F125-L429 HydrophobicContact CE1-CB 3.85Å; F125-L429 HydrophobicContact CE1-CD2 3.84Å; F125-L429 HydrophobicContact CE1-CG 4.29Å; F125-L429 VanDerWaalsContact CZ-O 3.28Å; F125-L429 WeakPolarHBondContact CZ-O 3.49Å; T129-L429 HydrophobicContact CG2-CD1 3.9Å; T129-L429 HydrophobicContact CG2-CD2 3.64Å; T129-L429 HydrophobicContact CG2-CG 4.36Å; M132-L429 HydrophobicContact CE-CD2 3.97Å; M132-L429 HydrophobicContact CE-CG 4.49Å; F425-L429 HydrophobicContact CD1-CD1 3.98Å; F425-L429 HydrophobicContact CE1-CD1 3.43Å; F425-L429 VanDerWaalsContact CE1-CD1 3.43Å; F425-L429 HydrophobicContact CE1-CG 4.34Å; F425-L429 HydrophobicContact CZ-CD1 3.86Å; F425-L429 WeakPolarHBondContact O-CG 3.47Å; F425-L429 PolarHBondContact O-N 3.45Å; F425-L429 VanDerWaalsContact O-N 3.14Å; V426-L429 PolarHBondContact O-N 3.34Å; L429-G431 VanDerWaalsContact C-N 3.34Å; L429-L432 PolarHBondContact O-N 2.88Å; L429-C433 PolarHBondContact O-N 3.41Å
430	I	92.8	Very high	89.6	Confident	93 Å²	93	38.8 Å²	38.8	48%	0.477	22%	0.222	S	C	.	.	H	α-helix	trans	-62.9	-43.3	174.5	-67.9	170.1	0	0	0	110.5	V426 L432 C433 L434	V426-I430 HydrophobicContact CG1-CD1 3.64Å; V426-I430 HydrophobicContact CG1-CG1 4.23Å; V426-I430 VanDerWaalsContact O-CG1 3.32Å; V426-I430 WeakPolarHBondContact O-CG1 3.29Å; V426-I430 PolarHBondContact O-N 3.03Å; I430-L432 VanDerWaalsContact C-N 3.32Å; I430-L432 PolarHBondContact O-N 2.91Å; I430-C433 WeakPolarHBondContact O-CB 3.34Å; I430-C433 PolarHBondContact O-N 3.29Å; I430-L434 WeakPolarHBondContact O-CB 3.17Å; I430-L434 PolarHBondContact O-N 3.2Å
431	G	92.1	Very high	89.1	Confident	0 Å²	0	43.3 Å²	43.3	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-59.6	-42	175.3	0	0	0	0	0	112.5	A427 I428 L429 L434 T435	A427-G431 PolarHBondContact O-N 2.89Å; I428-G431 PolarHBondContact O-N 3.26Å; L429-G431 VanDerWaalsContact C-N 3.34Å; G431-L434 PolarHBondContact O-N 2.99Å; G431-T435 WeakPolarHBondContact O-CG2 3.47Å; G431-T435 PolarHBondContact O-N 3.36Å
432	L	89.1	Confident	88.4	Confident	3 Å²	3	49 Å²	49	2%	0.016	27%	0.274	C	S	.	.	H	α-helix	trans	-65.2	-46.8	176.7	-156.4	158.3	0	0	0	110.5	F125 V128 Y403 I428 L429 I430 L434 T435 L436 S452	F125-L432 HydrophobicContact CD2-CD2 3.88Å; F125-L432 HydrophobicContact CE2-CB 4.23Å; F125-L432 HydrophobicContact CE2-CD2 3.31Å; F125-L432 HydrophobicContact CE2-CG 4.24Å; F125-L432 HydrophobicContact CZ-CB 4.12Å; F125-L432 HydrophobicContact CZ-CD2 4.08Å; V128-L432 HydrophobicContact CG1-CD1 4.33Å; V128-L432 HydrophobicContact CG2-CD1 4.35Å; Y403-L432 HydrophobicContact CE2-CD1 4.02Å; I428-L432 WeakPolarHBondContact O-CB 3.49Å; I428-L432 PolarHBondContact O-N 2.94Å; L429-L432 PolarHBondContact O-N 2.88Å; I430-L432 VanDerWaalsContact C-N 3.32Å; I430-L432 PolarHBondContact O-N 2.91Å; L432-L434 VanDerWaalsContact C-N 3.29Å; L432-L434 PolarHBondContact O-N 3.32Å; L432-T435 WeakPolarHBondContact CA-OG1 3.42Å; L432-T435 PolarHBondContact O-N 3.31Å; L432-T435 PolarHBondContact O-OG1 3.49Å; L432-L436 HydrophobicContact CD2-CD1 3.54Å; L432-L436 HydrophobicContact CD2-CG 3.9Å; L432-L436 WeakPolarHBondContact O-CG 3.38Å; L432-L436 PolarHBondContact O-N 3.36Å; L432-S452 PolarHBondContact N-OG 2.91Å; L432-S452 VanDerWaalsContact N-OG 3.16Å
433	C	88.6	Confident	87.5	Confident	61 Å²	61	53 Å²	53	41%	0.412	29%	0.287	S	S	.	.	H	α-helix	trans	-52.4	-48.3	172.2	-88.3	0	0	0	0	111.5	F125 L429 I430 L436 L437	F125-C433 HydrophobicContact CZ-CB 4.15Å; F125-C433 WeakPolarHBondContact CZ-SG 3.27Å; L429-C433 PolarHBondContact O-N 3.41Å; I430-C433 WeakPolarHBondContact O-CB 3.34Å; I430-C433 PolarHBondContact O-N 3.29Å; C433-L436 PolarHBondContact O-N 2.94Å; C433-L437 WeakPolarHBondContact O-CB 3.39Å; C433-L437 PolarHBondContact O-N 3.1Å
434	L	89	Confident	86.3	Confident	62 Å²	62	59.3 Å²	59.3	33%	0.325	31%	0.31	S	S	.	.	H	α-helix	trans	-64.7	-42	-179	-168.6	145.7	0	0	0	111	I430 G431 L432 L436 L437 L438 I451 F455	I430-L434 WeakPolarHBondContact O-CB 3.17Å; I430-L434 PolarHBondContact O-N 3.2Å; G431-L434 PolarHBondContact O-N 2.99Å; L432-L434 VanDerWaalsContact C-N 3.29Å; L432-L434 PolarHBondContact O-N 3.32Å; L434-L436 VanDerWaalsContact C-N 3.35Å; L434-L436 PolarHBondContact O-N 3.48Å; L434-L437 PolarHBondContact O-N 3.13Å; L434-L438 HydrophobicContact CD2-CD1 3.49Å; L434-L438 VanDerWaalsContact CD2-CD1 3.49Å; L434-L438 HydrophobicContact CD2-CD2 4.18Å; L434-L438 HydrophobicContact CD2-CG 4.44Å; L434-L438 HydrophobicContact CG-CD1 3.88Å; L434-L438 WeakPolarHBondContact O-CD1 3.02Å; L434-L438 PolarHBondContact O-N 3.39Å; L434-I451 HydrophobicContact CD2-CD1 4.09Å; L434-I451 HydrophobicContact CD2-CG2 3.74Å; L434-F455 HydrophobicContact CD1-CE2 4.18Å; L434-F455 HydrophobicContact CD1-CZ 4.41Å
435	T	87.3	Confident	85.1	Confident	3 Å²	3	63.6 Å²	63.6	2%	0.018	35%	0.346	C	S	.	.	H	α-helix	trans	-61	-42.2	176.2	62.7	0	0	0	0	112.3	G431 L432 L438 L439 A448 I451	G431-T435 WeakPolarHBondContact O-CG2 3.47Å; G431-T435 PolarHBondContact O-N 3.36Å; L432-T435 WeakPolarHBondContact CA-OG1 3.42Å; L432-T435 PolarHBondContact O-N 3.31Å; L432-T435 PolarHBondContact O-OG1 3.49Å; T435-L438 PolarHBondContact O-N 3.26Å; T435-L439 VanDerWaalsContact O-CG 3.28Å; T435-L439 WeakPolarHBondContact O-CG 3.43Å; T435-L439 PolarHBondContact O-N 2.83Å; T435-A448 WeakPolarHBondContact CG2-O 3.07Å; T435-I451 HydrophobicContact CG2-CB 3.58Å; T435-I451 HydrophobicContact CG2-CD1 3.83Å; T435-I451 HydrophobicContact CG2-CG1 4.16Å; T435-I451 HydrophobicContact CG2-CG2 3.96Å
436	L	82.7	Confident	83.9	Confident	31 Å²	31	64 Å²	64	16%	0.162	35%	0.35	C	S	.	.	H	α-helix	trans	-66.2	-39.7	177.1	-66.6	179.2	0	0	0	111.7	V121 L124 F125 L432 C433 L434 L439 A440	V121-L436 HydrophobicContact CB-CD1 4.13Å; V121-L436 HydrophobicContact CG1-CD1 4.03Å; V121-L436 HydrophobicContact CG2-CD1 3.67Å; L124-L436 HydrophobicContact CD1-CD1 4.07Å; L124-L436 HydrophobicContact CD1-CD2 3.87Å; F125-L436 HydrophobicContact CE2-CD1 4.23Å; L432-L436 HydrophobicContact CD2-CD1 3.54Å; L432-L436 HydrophobicContact CD2-CG 3.9Å; L432-L436 WeakPolarHBondContact O-CG 3.38Å; L432-L436 PolarHBondContact O-N 3.36Å; C433-L436 PolarHBondContact O-N 2.94Å; L434-L436 VanDerWaalsContact C-N 3.35Å; L434-L436 PolarHBondContact O-N 3.48Å; L436-L439 HydrophobicContact CD2-CD1 4.19Å; L436-L439 WeakPolarHBondContact O-CB 3.31Å; L436-L439 PolarHBondContact O-N 3.4Å; L436-A440 PolarHBondContact O-N 2.87Å
437	L	84.4	Confident	83	Confident	110 Å²	110	61.5 Å²	61.5	58%	0.576	34%	0.335	S	S	*	.	H	α-helix	trans	-63.2	-44.1	174.5	-170	157.1	0	0	0	111.2	C433 L434 L439 A440 V441	C433-L437 WeakPolarHBondContact O-CB 3.39Å; C433-L437 PolarHBondContact O-N 3.1Å; L434-L437 PolarHBondContact O-N 3.13Å; L437-L439 VanDerWaalsContact C-N 3.33Å; L437-L439 PolarHBondContact O-N 3.45Å; L437-A440 WeakPolarHBondContact O-CB 3.43Å; L437-A440 PolarHBondContact O-N 3Å; L437-V441 HydrophobicContact CD2-CG2 4.02Å; L437-V441 WeakPolarHBondContact O-CG2 3.23Å; L437-V441 PolarHBondContact O-N 3.48Å
438	L	82.6	Confident	82	Confident	43 Å²	43	62.1 Å²	62.1	23%	0.225	34%	0.34	C	S	.	.	H	α-helix	trans	-64.1	-37.5	176.8	-94.2	70.2	0	0	0	112.2	L434 T435 A440 V441 F442 L446 I451	L434-L438 HydrophobicContact CD2-CD1 3.49Å; L434-L438 VanDerWaalsContact CD2-CD1 3.49Å; L434-L438 HydrophobicContact CD2-CD2 4.18Å; L434-L438 HydrophobicContact CD2-CG 4.44Å; L434-L438 HydrophobicContact CG-CD1 3.88Å; L434-L438 WeakPolarHBondContact O-CD1 3.02Å; L434-L438 PolarHBondContact O-N 3.39Å; T435-L438 PolarHBondContact O-N 3.26Å; L438-A440 VanDerWaalsContact C-N 3.33Å; L438-V441 PolarHBondContact O-N 2.95Å; L438-F442 HydrophobicContact CB-CD2 4.16Å; L438-F442 HydrophobicContact CB-CE2 4.42Å; L438-F442 HydrophobicContact CD2-CE2 4.12Å; L438-F442 HydrophobicContact CG-CD2 4.16Å; L438-F442 HydrophobicContact CG-CE2 3.91Å; L438-F442 WeakPolarHBondContact O-CB 3.36Å; L438-F442 VanDerWaalsContact O-CD2 3.31Å; L438-F442 WeakPolarHBondContact O-CD2 3.5Å; L438-F442 PolarHBondContact O-N 3.37Å; L438-L446 HydrophobicContact CB-CD1 3.98Å; L438-I451 HydrophobicContact CD2-CD1 4.03Å
439	L	77.4	Confident	81.4	Confident	52 Å²	52	62.3 Å²	62.3	27%	0.272	34%	0.341	S	S	.	.	H	α-helix	trans	-61.4	-42.4	173.2	-74.4	170.9	0	0	0	111.5	T435 L436 L437 K443 K444 L446	T435-L439 VanDerWaalsContact O-CG 3.28Å; T435-L439 WeakPolarHBondContact O-CG 3.43Å; T435-L439 PolarHBondContact O-N 2.83Å; L436-L439 HydrophobicContact CD2-CD1 4.19Å; L436-L439 WeakPolarHBondContact O-CB 3.31Å; L436-L439 PolarHBondContact O-N 3.4Å; L437-L439 VanDerWaalsContact C-N 3.33Å; L437-L439 PolarHBondContact O-N 3.45Å; L439-K443 PolarHBondContact O-N 3.34Å; L439-K443 VanDerWaalsContact O-N 3.1Å; L439-K444 WeakPolarHBondContact CD2-O 3.37Å; L439-L446 HydrophobicContact CD2-CB 3.73Å; L439-L446 HydrophobicContact CD2-CD1 4.46Å; L439-L446 HydrophobicContact CD2-CG 4.22Å; L439-L446 HydrophobicContact CG-CB 4.44Å
440	A	76.8	Confident	81.2	Confident	74 Å²	74	61.6 Å²	61.6	61%	0.612	34%	0.338	S	S	*	.	H	α-helix	trans	-64.4	-40.1	177.9	0	0	0	0	0	112.3	L436 L437 L438	L436-A440 PolarHBondContact O-N 2.87Å; L437-A440 WeakPolarHBondContact O-CB 3.43Å; L437-A440 PolarHBondContact O-N 3Å; L438-A440 VanDerWaalsContact C-N 3.33Å
441	V	81.3	Confident	81.1	Confident	100 Å²	100	59.4 Å²	59.4	61%	0.606	33%	0.327	S	S	*	.	H	α-helix	trans	-75.9	-46.8	-179.4	175	0	0	0	0	112.1	L437 L438	L437-V441 HydrophobicContact CD2-CG2 4.02Å; L437-V441 WeakPolarHBondContact O-CG2 3.23Å; L437-V441 PolarHBondContact O-N 3.48Å; L438-V441 PolarHBondContact O-N 2.95Å
442	F	77.8	Confident	81.1	Confident	124 Å²	124	59.4 Å²	59.4	54%	0.544	33%	0.327	S	S	.	.	H	α-helix	trans	-85.6	-10.9	-172.3	-69.7	-57.3	0	0	0	114.3	L438 K444 L446	L438-F442 HydrophobicContact CB-CD2 4.16Å; L438-F442 HydrophobicContact CB-CE2 4.42Å; L438-F442 HydrophobicContact CD2-CE2 4.12Å; L438-F442 HydrophobicContact CG-CD2 4.16Å; L438-F442 HydrophobicContact CG-CE2 3.91Å; L438-F442 WeakPolarHBondContact O-CB 3.36Å; L438-F442 VanDerWaalsContact O-CD2 3.31Å; L438-F442 WeakPolarHBondContact O-CD2 3.5Å; L438-F442 PolarHBondContact O-N 3.37Å; F442-K444 WeakPolarHBondContact O-CG 3.37Å; F442-K444 PolarHBondContact O-N 2.62Å; F442-L446 HydrophobicContact CD2-CD1 4.1Å
443	K	75.2	Confident	81.3	Confident	196 Å²	196	59.3 Å²	59.3	85%	0.852	33%	0.326	S	S	*	.			trans	46	29.4	-176.6	-61.5	-166.5	177.8	-177.1	0	113.7	L439	L439-K443 PolarHBondContact O-N 3.34Å; L439-K443 VanDerWaalsContact O-N 3.1Å
444	K	69.3	Low	81.5	Confident	154 Å²	154	59.5 Å²	59.5	67%	0.67	33%	0.326	S	S	*	.	S	Bend	trans	-125	141.4	179.7	-77.1	-179.6	179.6	177.3	0	108.6	L439 F442 L446	L439-K444 WeakPolarHBondContact CD2-O 3.37Å; F442-K444 WeakPolarHBondContact O-CG 3.37Å; F442-K444 PolarHBondContact O-N 2.62Å; K444-L446 PolarHBondContact O-N 2.75Å; K444-L446 VanDerWaalsContact O-N 3.12Å
445	A	66.8	Low	81.7	Confident	90 Å²	90	59.9 Å²	59.9	74%	0.744	33%	0.325	S	S	*	.			trans	-65.2	112.3	173.5	0	0	0	0	0	109.8
446	L	70.9	Confident	82	Confident	55 Å²	55	59.8 Å²	59.8	29%	0.288	32%	0.324	S	S	.	.			trans	-107.6	143.2	175	-67.9	166.8	0	0	0	109.5	L438 L439 F442 K444 A448	L438-L446 HydrophobicContact CB-CD1 3.98Å; L439-L446 HydrophobicContact CD2-CB 3.73Å; L439-L446 HydrophobicContact CD2-CD1 4.46Å; L439-L446 HydrophobicContact CD2-CG 4.22Å; L439-L446 HydrophobicContact CG-CB 4.44Å; F442-L446 HydrophobicContact CD2-CD1 4.1Å; K444-L446 PolarHBondContact O-N 2.75Å; K444-L446 VanDerWaalsContact O-N 3.12Å; L446-A448 PolarHBondContact O-N 2.92Å
447	P	76.1	Confident	82.5	Confident	11 Å²	11	59.5 Å²	59.5	7%	0.071	32%	0.323	C	S	.	.			trans	-64.9	126.5	171	24	-27.8	0	0	0	109.7	D296 L297 V300 P450	D296-P447 WeakPolarHBondContact OD2-CB 3.49Å; L297-P447 HydrophobicContact CD1-CG 3.74Å; V300-P447 HydrophobicContact CB-CB 4.36Å; V300-P447 HydrophobicContact CB-CG 4.29Å; V300-P447 HydrophobicContact CG1-CG 4.41Å; V300-P447 HydrophobicContact CG2-CB 4.21Å; P447-P450 HydrophobicContact CB-CG 4.01Å; P447-P450 HydrophobicContact CG-CG 3.9Å; P447-P450 WeakPolarHBondContact O-CD 3.23Å
448	A	74.3	Confident	83	Confident	14 Å²	14	59 Å²	59	12%	0.116	32%	0.319	C	S	.	.	S	Bend	trans	-79.6	-26.5	-178.4	0	0	0	0	0	112.9	L395 Y403 T435 L446 S452	L395-A448 HydrophobicContact CD1-CB 4.27Å; Y403-A448 PolarHBondContact OH-O 3.46Å; T435-A448 WeakPolarHBondContact CG2-O 3.07Å; L446-A448 PolarHBondContact O-N 2.92Å; A448-S452 PolarHBondContact O-OG 3.25Å
449	L	82	Confident	83.5	Confident	5 Å²	5	61.1 Å²	61.1	3%	0.026	33%	0.327	C	S	.	.	H	α-helix	trans	-62.1	-47.5	-176.6	-166.4	159.2	0	0	0	114.3	I292 S293 F402 I451 I453	I292-L449 HydrophobicContact CG2-CD1 4.43Å; S293-L449 VanDerWaalsContact CA-CD2 3.5Å; F402-L449 HydrophobicContact CB-CD1 4.4Å; F402-L449 HydrophobicContact CD2-CD1 3.47Å; F402-L449 VanDerWaalsContact CD2-CD1 3.47Å; F402-L449 HydrophobicContact CE2-CD1 4.12Å; F402-L449 HydrophobicContact CG-CD1 4.23Å; L449-I451 PolarHBondContact O-N 3.37Å; L449-I453 HydrophobicContact CD2-CB 4.39Å; L449-I453 HydrophobicContact CD2-CG1 3.71Å; L449-I453 HydrophobicContact CG-CG1 4.11Å; L449-I453 WeakPolarHBondContact O-CB 3.26Å; L449-I453 VanDerWaalsContact O-CG1 3.29Å; L449-I453 WeakPolarHBondContact O-CG1 3.27Å; L449-I453 PolarHBondContact O-N 3.5Å
450	P	88.5	Confident	84.3	Confident	13 Å²	13	59.1 Å²	59.1	8%	0.084	32%	0.316	C	S	.	.	H	α-helix	trans	-67.7	-41	-166.7	21.1	-32.7	0	0	0	115.3	L297 P447 T454	L297-P450 HydrophobicContact CB-CG 4.41Å; L297-P450 HydrophobicContact CD1-CG 4.3Å; P447-P450 HydrophobicContact CB-CG 4.01Å; P447-P450 HydrophobicContact CG-CG 3.9Å; P447-P450 WeakPolarHBondContact O-CD 3.23Å; P450-T454 VanDerWaalsContact O-CB 3.27Å; P450-T454 WeakPolarHBondContact O-CB 3.46Å; P450-T454 PolarHBondContact O-N 3.45Å; P450-T454 PolarHBondContact O-OG1 3.11Å
451	I	90.2	Very high	85	Confident	47 Å²	47	59.7 Å²	59.7	24%	0.241	31%	0.305	C	S	.	.	H	α-helix	trans	-65.8	-48.9	-178.5	-66.8	175.3	0	0	0	109.7	L434 T435 L438 L449 T454 F455	L434-I451 HydrophobicContact CD2-CD1 4.09Å; L434-I451 HydrophobicContact CD2-CG2 3.74Å; T435-I451 HydrophobicContact CG2-CB 3.58Å; T435-I451 HydrophobicContact CG2-CD1 3.83Å; T435-I451 HydrophobicContact CG2-CG1 4.16Å; T435-I451 HydrophobicContact CG2-CG2 3.96Å; L438-I451 HydrophobicContact CD2-CD1 4.03Å; L449-I451 PolarHBondContact O-N 3.37Å; I451-T454 PolarHBondContact O-N 2.92Å; I451-F455 HydrophobicContact CG2-CD2 3.8Å; I451-F455 HydrophobicContact CG2-CE2 3.65Å; I451-F455 WeakPolarHBondContact O-CD2 3.32Å; I451-F455 PolarHBondContact O-N 2.99Å
452	S	92.6	Very high	85.6	Confident	0 Å²	0	57.3 Å²	57.3	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-64	-43	-178.6	-51.7	0	0	0	0	112.7	L432 A448 G456	L432-S452 PolarHBondContact N-OG 2.91Å; L432-S452 VanDerWaalsContact N-OG 3.16Å; A448-S452 PolarHBondContact O-OG 3.25Å; S452-G456 PolarHBondContact O-N 3.5Å
453	I	93.1	Very high	86.3	Confident	0 Å²	0	51.9 Å²	51.9	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-67.3	-39.5	176.2	-67.3	-64.3	0	0	0	111.3	L289 F402 Y403 L406 L449 G456 L457	L289-I453 HydrophobicContact CB-CG2 4.32Å; F402-I453 HydrophobicContact CB-CD1 4.18Å; Y403-I453 HydrophobicContact CD1-CD1 3.95Å; Y403-I453 HydrophobicContact CD1-CG1 4.49Å; Y403-I453 HydrophobicContact CE1-CD1 4.33Å; Y403-I453 HydrophobicContact CE1-CG1 4.37Å; L406-I453 HydrophobicContact CB-CD1 4.43Å; L406-I453 HydrophobicContact CD1-CD1 3.8Å; L406-I453 HydrophobicContact CD1-CG2 4.32Å; L449-I453 HydrophobicContact CD2-CB 4.39Å; L449-I453 HydrophobicContact CD2-CG1 3.71Å; L449-I453 HydrophobicContact CG-CG1 4.11Å; L449-I453 WeakPolarHBondContact O-CB 3.26Å; L449-I453 VanDerWaalsContact O-CG1 3.29Å; L449-I453 WeakPolarHBondContact O-CG1 3.27Å; L449-I453 PolarHBondContact O-N 3.5Å; I453-G456 PolarHBondContact O-N 2.9Å; I453-L457 HydrophobicContact CG2-CD1 3.9Å; I453-L457 HydrophobicContact CG2-CG 4.19Å; I453-L457 WeakPolarHBondContact O-CB 3.46Å; I453-L457 VanDerWaalsContact O-CG 3.29Å; I453-L457 WeakPolarHBondContact O-CG 3.41Å; I453-L457 PolarHBondContact O-N 2.89Å
454	T	93.3	Very high	87	Confident	66 Å²	66	44.4 Å²	44.4	41%	0.405	24%	0.239	S	C	.	.	H	α-helix	trans	-63.1	-46.7	178.5	-57.4	0	0	0	0	111.1	P450 I451 L457 I458	P450-T454 VanDerWaalsContact O-CB 3.27Å; P450-T454 WeakPolarHBondContact O-CB 3.46Å; P450-T454 PolarHBondContact O-N 3.45Å; P450-T454 PolarHBondContact O-OG1 3.11Å; I451-T454 PolarHBondContact O-N 2.92Å; T454-L457 PolarHBondContact O-N 3.44Å; T454-I458 HydrophobicContact CG2-CD1 3.9Å; T454-I458 VanDerWaalsContact O-CG1 3.29Å; T454-I458 WeakPolarHBondContact O-CG1 3.17Å; T454-I458 PolarHBondContact O-N 2.91Å
455	F	93.9	Very high	88	Confident	70 Å²	70	42 Å²	42	31%	0.307	23%	0.233	S	C	.	.	H	α-helix	trans	-60.9	-45.1	173.5	-78.4	-54.2	0	0	0	111.9	A427 L434 I451 L457 I458 F459	A427-F455 HydrophobicContact CB-CB 4.42Å; L434-F455 HydrophobicContact CD1-CE2 4.18Å; L434-F455 HydrophobicContact CD1-CZ 4.41Å; I451-F455 HydrophobicContact CG2-CD2 3.8Å; I451-F455 HydrophobicContact CG2-CE2 3.65Å; I451-F455 WeakPolarHBondContact O-CD2 3.32Å; I451-F455 PolarHBondContact O-N 2.99Å; F455-L457 VanDerWaalsContact C-N 3.35Å; F455-L457 PolarHBondContact O-N 3.44Å; F455-I458 PolarHBondContact O-N 2.86Å; F455-F459 WeakPolarHBondContact O-CB 3.29Å; F455-F459 WeakPolarHBondContact O-CD2 3.24Å; F455-F459 PolarHBondContact O-N 3.34Å
456	G	93.2	Very high	89.2	Confident	0 Å²	0	43.3 Å²	43.3	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-57.6	-43.6	176.8	0	0	0	0	0	113.1	S452 I453 Y460	S452-G456 PolarHBondContact O-N 3.5Å; I453-G456 PolarHBondContact O-N 2.9Å; G456-Y460 VanDerWaalsContact O-CB 3.27Å; G456-Y460 WeakPolarHBondContact O-CB 3.17Å; G456-Y460 PolarHBondContact O-N 3.04Å
457	L	93.6	Very high	90.1	Very high	26 Å²	26	43.5 Å²	43.5	14%	0.136	23%	0.23	C	C	.	.	H	α-helix	trans	-67	-44.3	177.5	-70.7	174.4	0	0	0	112	W286 L289 L406 I453 T454 F455 Y460 F461	W286-L457 HydrophobicContact CE3-CD2 3.44Å; W286-L457 VanDerWaalsContact CE3-CD2 3.44Å; W286-L457 HydrophobicContact CZ3-CD2 3.9Å; L289-L457 HydrophobicContact CB-CD2 4.5Å; L406-L457 HydrophobicContact CD1-CD2 4.35Å; L406-L457 HydrophobicContact CD1-CG 4.26Å; I453-L457 HydrophobicContact CG2-CD1 3.9Å; I453-L457 HydrophobicContact CG2-CG 4.19Å; I453-L457 WeakPolarHBondContact O-CB 3.46Å; I453-L457 VanDerWaalsContact O-CG 3.29Å; I453-L457 WeakPolarHBondContact O-CG 3.41Å; I453-L457 PolarHBondContact O-N 2.89Å; T454-L457 PolarHBondContact O-N 3.44Å; F455-L457 VanDerWaalsContact C-N 3.35Å; F455-L457 PolarHBondContact O-N 3.44Å; L457-Y460 PolarHBondContact O-N 3.49Å; L457-F461 HydrophobicContact CD2-CE2 4.49Å; L457-F461 WeakPolarHBondContact O-CD2 3.41Å; L457-F461 PolarHBondContact O-N 3Å
458	I	94.5	Very high	90.7	Very high	98 Å²	98	46 Å²	46	50%	0.503	24%	0.238	S	C	.	.	H	α-helix	trans	-61	-48	177.9	-69.8	168	0	0	0	110.3	T454 F455 F461 S462	T454-I458 HydrophobicContact CG2-CD1 3.9Å; T454-I458 VanDerWaalsContact O-CG1 3.29Å; T454-I458 WeakPolarHBondContact O-CG1 3.17Å; T454-I458 PolarHBondContact O-N 2.91Å; F455-I458 PolarHBondContact O-N 2.86Å; I458-F461 PolarHBondContact O-N 3.33Å; I458-S462 WeakPolarHBondContact O-CB 3.16Å; I458-S462 PolarHBondContact O-N 3.37Å
459	F	93.8	Very high	91.5	Very high	89 Å²	89	48.4 Å²	48.4	39%	0.39	25%	0.253	S	S	.	.	H	α-helix	trans	-66.1	-39.1	178	-88.8	-106.6	0	0	0	111.7	A423 A427 F455 S462 T463	A423-F459 HydrophobicContact CB-CD1 4.45Å; A427-F459 HydrophobicContact CB-CB 3.77Å; A427-F459 HydrophobicContact CB-CD1 4.24Å; A427-F459 HydrophobicContact CB-CD2 3.89Å; A427-F459 HydrophobicContact CB-CG 3.69Å; F455-F459 WeakPolarHBondContact O-CB 3.29Å; F455-F459 WeakPolarHBondContact O-CD2 3.24Å; F455-F459 PolarHBondContact O-N 3.34Å; F459-S462 PolarHBondContact O-N 3.28Å; F459-T463 WeakPolarHBondContact O-CB 3.39Å; F459-T463 PolarHBondContact O-N 3.36Å; F459-T463 PolarHBondContact O-OG1 2.8Å
460	Y	92.8	Very high	91.9	Very high	9 Å²	9	53.7 Å²	53.7	4%	0.035	28%	0.276	C	S	.	.	H	α-helix	trans	-54.9	-57.2	174	175.8	-98.9	0	0	0	111.5	W286 A410 T413 T420 C424 G456 L457 T463 D464	W286-Y460 HydrophobicContact CD2-CD1 4.41Å; W286-Y460 HydrophobicContact CD2-CE1 4.21Å; W286-Y460 AromaticContact CE2-CE1 3.59Å; W286-Y460 AromaticContact CE2-CZ 3.78Å; W286-Y460 HydrophobicContact CE3-CD1 4.27Å; W286-Y460 HydrophobicContact CE3-CE1 4.49Å; W286-Y460 AromaticContact CH2-CD1 3.67Å; W286-Y460 HydrophobicContact CH2-CD1 3.67Å; W286-Y460 AromaticContact CH2-CD2 3.46Å; W286-Y460 HydrophobicContact CH2-CD2 3.46Å; W286-Y460 VanDerWaalsContact CH2-CD2 3.46Å; W286-Y460 AromaticContact CH2-CE1 3.67Å; W286-Y460 HydrophobicContact CH2-CE1 3.67Å; W286-Y460 AromaticContact CH2-CE2 3.46Å; W286-Y460 HydrophobicContact CH2-CE2 3.46Å; W286-Y460 VanDerWaalsContact CH2-CE2 3.46Å; W286-Y460 AromaticContact CH2-CG 3.57Å; W286-Y460 HydrophobicContact CH2-CG 3.57Å; W286-Y460 AromaticContact CH2-CZ 3.56Å; W286-Y460 AromaticContact CZ2-CD1 3.85Å; W286-Y460 HydrophobicContact CZ2-CD1 3.85Å; W286-Y460 AromaticContact CZ2-CD2 3.97Å; W286-Y460 HydrophobicContact CZ2-CD2 3.97Å; W286-Y460 AromaticContact CZ2-CE1 3.33Å; W286-Y460 HydrophobicContact CZ2-CE1 3.33Å; W286-Y460 AromaticContact CZ2-CE2 3.47Å; W286-Y460 HydrophobicContact CZ2-CE2 3.47Å; W286-Y460 VanDerWaalsContact CZ2-CE2 3.47Å; W286-Y460 HydrophobicContact CZ2-CG 4.14Å; W286-Y460 AromaticContact CZ2-CZ 3.11Å; W286-Y460 WeakPolarHBondContact CZ2-OH 3.14Å; W286-Y460 AromaticContact CZ3-CD1 3.88Å; W286-Y460 HydrophobicContact CZ3-CD1 3.88Å; W286-Y460 HydrophobicContact CZ3-CD2 4.2Å; W286-Y460 HydrophobicContact CZ3-CE1 4.23Å; W286-Y460 AromaticContact CZ3-CG 3.87Å; W286-Y460 HydrophobicContact CZ3-CG 3.87Å; A410-Y460 HydrophobicContact CB-CD2 3.7Å; A410-Y460 HydrophobicContact CB-CE2 3.85Å; T413-Y460 PolarHBondContact OG1-OH 3.27Å; T420-Y460 HydrophobicContact CG2-CD2 3.54Å; T420-Y460 HydrophobicContact CG2-CE2 3.79Å; T420-Y460 HydrophobicContact CG2-CG 4.48Å; C424-Y460 VanDerWaalsContact SG-CB 3.58Å; G456-Y460 VanDerWaalsContact O-CB 3.27Å; G456-Y460 WeakPolarHBondContact O-CB 3.17Å; G456-Y460 PolarHBondContact O-N 3.04Å; L457-Y460 PolarHBondContact O-N 3.49Å; Y460-T463 PolarHBondContact O-N 2.91Å; Y460-D464 VanDerWaalsContact O-CB 3.26Å; Y460-D464 WeakPolarHBondContact O-CB 3.27Å; Y460-D464 PolarHBondContact O-N 3.31Å
461	F	92.3	Very high	92	Very high	87 Å²	87	55.3 Å²	55.3	38%	0.382	28%	0.283	S	S	.	.	H	α-helix	trans	-69	-37.5	-176.9	-72.3	-66.2	0	0	0	112.4	W286 L457 I458 N465	W286-F461 HydrophobicContact CB-CZ 4.3Å; W286-F461 HydrophobicContact CD2-CZ 4.4Å; W286-F461 HydrophobicContact CG-CZ 4.16Å; L457-F461 HydrophobicContact CD2-CE2 4.49Å; L457-F461 WeakPolarHBondContact O-CD2 3.41Å; L457-F461 PolarHBondContact O-N 3Å; I458-F461 PolarHBondContact O-N 3.33Å; F461-N465 VanDerWaalsContact O-CB 3.31Å; F461-N465 WeakPolarHBondContact O-CB 3.31Å; F461-N465 PolarHBondContact O-N 3.29Å; F461-N465 PolarHBondContact O-ND2 2.89Å
462	S	93.1	Very high	92	Very high	50 Å²	50	56.4 Å²	56.4	35%	0.35	29%	0.289	S	S	.	.	H	α-helix	trans	-64.5	-46.2	176	-176.1	0	0	0	0	111.4	I458 F459 L466 V467	I458-S462 WeakPolarHBondContact O-CB 3.16Å; I458-S462 PolarHBondContact O-N 3.37Å; F459-S462 PolarHBondContact O-N 3.28Å; S462-L466 WeakPolarHBondContact O-CA 3.26Å; S462-L466 VanDerWaalsContact O-CB 3.26Å; S462-L466 WeakPolarHBondContact O-CB 3.46Å; S462-L466 PolarHBondContact O-N 2.7Å; S462-V467 PolarHBondContact O-N 3.02Å
463	T	91.9	Very high	92	Very high	9 Å²	9	60.2 Å²	60.2	6%	0.055	31%	0.312	C	S	.	.	I	π-helix	trans	-68.3	-42.7	180	-58.9	0	0	0	0	111.5	T420 A423 F459 Y460 V467 R468	T420-T463 HydrophobicContact CG2-CG2 4.44Å; A423-T463 HydrophobicContact CB-CG2 4.07Å; A423-T463 WeakPolarHBondContact CB-OG1 3.4Å; F459-T463 WeakPolarHBondContact O-CB 3.39Å; F459-T463 PolarHBondContact O-N 3.36Å; F459-T463 PolarHBondContact O-OG1 2.8Å; Y460-T463 PolarHBondContact O-N 2.91Å; T463-V467 HydrophobicContact CG2-CB 4.07Å; T463-V467 HydrophobicContact CG2-CG1 4.41Å; T463-V467 PolarHBondContact O-N 2.93Å; T463-R468 WeakPolarHBondContact O-CB 3.37Å; T463-R468 PolarHBondContact O-N 2.87Å
464	D	89.8	Confident	91.9	Very high	40 Å²	40	61.2 Å²	61.2	21%	0.214	32%	0.318	C	S	.	.	I	π-helix	trans	-68	-39.6	-179.7	-168.4	49.8	0	0	0	112.8	T420 Y460 R468	T420-D464 HydrophobicContact CG2-CB 4.46Å; Y460-D464 VanDerWaalsContact O-CB 3.26Å; Y460-D464 WeakPolarHBondContact O-CB 3.27Å; Y460-D464 PolarHBondContact O-N 3.31Å; D464-R468 IonicContact OD1-NH1 3.27Å; D464-R468 PolarHBondContact OD1-NH1 3.22Å
465	N	90.3	Very high	91.8	Very high	102 Å²	102	61.2 Å²	61.2	55%	0.545	33%	0.325	S	S	.	.	I	π-helix	trans	-91.9	-29.4	-175.7	-66.9	-83.3	0	0	0	114.6	F461 P469	F461-N465 VanDerWaalsContact O-CB 3.31Å; F461-N465 WeakPolarHBondContact O-CB 3.31Å; F461-N465 PolarHBondContact O-N 3.29Å; F461-N465 PolarHBondContact O-ND2 2.89Å; N465-P469 WeakPolarHBondContact O-CG 3.49Å
466	L	92	Very high	91.9	Very high	118 Å²	118	62 Å²	62	62%	0.618	34%	0.339	S	S	*	.	I	π-helix	trans	-113.2	-57	-173.6	-56.2	175.2	0	0	0	112.3	S462 P469 F470	S462-L466 WeakPolarHBondContact O-CA 3.26Å; S462-L466 VanDerWaalsContact O-CB 3.26Å; S462-L466 WeakPolarHBondContact O-CB 3.46Å; S462-L466 PolarHBondContact O-N 2.7Å; L466-P469 WeakPolarHBondContact O-CD 3.46Å; L466-P469 WeakPolarHBondContact O-CG 3.24Å; L466-F470 WeakPolarHBondContact O-CB 3.46Å
467	V	90.9	Very high	92	Very high	59 Å²	59	68.2 Å²	68.2	36%	0.358	37%	0.368	S	S	.	.	I	π-helix	trans	-70.2	-42.9	-170.9	-178.6	0	0	0	0	110.8	S462 T463 F470 M471	S462-V467 PolarHBondContact O-N 3.02Å; T463-V467 HydrophobicContact CG2-CB 4.07Å; T463-V467 HydrophobicContact CG2-CG1 4.41Å; T463-V467 PolarHBondContact O-N 2.93Å; V467-F470 WeakPolarHBondContact O-CB 3.12Å; V467-F470 PolarHBondContact O-N 3.49Å; V467-M471 HydrophobicContact CG1-CG 3.78Å; V467-M471 WeakPolarHBondContact O-CB 3.38Å; V467-M471 VanDerWaalsContact O-CG 3.24Å; V467-M471 WeakPolarHBondContact O-CG 3.44Å; V467-M471 PolarHBondContact O-N 2.81Å
468	R	88.4	Confident	92	Very high	63 Å²	63	74.1 Å²	74.1	24%	0.238	40%	0.395	C	S	.	.	H	α-helix	trans	-60.9	-55.7	-176.9	-179.6	-177.5	164.2	-164.1	0.6	113.7	S415 D417 T463 D464 F470 M471 D472	S415-R468 PolarHBondContact OG-NH1 2.95Å; S415-R468 PolarHBondContact OG-NH2 3.26Å; D417-R468 VanDerWaalsContact OD2-CD 3.24Å; D417-R468 WeakPolarHBondContact OD2-CD 3.31Å; D417-R468 IonicContact OD2-CZ 3.42Å; D417-R468 IonicContact OD2-NE 3.69Å; D417-R468 PolarHBondContact OD2-NE 3.16Å; D417-R468 IonicContact OD2-NH1 2.65Å; D417-R468 IonicContact OD2-NH2 2.76Å; D417-R468 PolarHBondContact OD2-NH2 2.82Å; T463-R468 WeakPolarHBondContact O-CB 3.37Å; T463-R468 PolarHBondContact O-N 2.87Å; D464-R468 IonicContact OD1-NH1 3.27Å; D464-R468 PolarHBondContact OD1-NH1 3.22Å; R468-F470 PolarHBondContact O-N 2.83Å; R468-M471 PolarHBondContact O-N 3.42Å; R468-M471 VanDerWaalsContact O-N 3.16Å; R468-D472 IonicContact NE-OD2 2.69Å; R468-D472 WeakPolarHBondContact O-CB 3.4Å; R468-D472 VanDerWaalsContact O-CG 3.24Å; R468-D472 PolarHBondContact O-N 3.36Å
469	P	90.8	Very high	91.9	Very high	65 Å²	65	74.6 Å²	74.6	42%	0.422	40%	0.398	S	S	.	.	H	α-helix	trans	-61.4	-31.8	178.9	23.3	-33.8	0	0	0	112.5	N465 L466 T473	N465-P469 WeakPolarHBondContact O-CG 3.49Å; L466-P469 WeakPolarHBondContact O-CD 3.46Å; L466-P469 WeakPolarHBondContact O-CG 3.24Å; P469-T473 WeakPolarHBondContact O-CB 3.47Å; P469-T473 PolarHBondContact O-N 3.07Å; P469-T473 VanDerWaalsContact O-N 3.12Å; P469-T473 PolarHBondContact O-OG1 3.4Å
470	F	91.1	Very high	91.8	Very high	116 Å²	116	80.1 Å²	80.1	51%	0.509	42%	0.417	S	S	.	.	H	α-helix	trans	-66.2	-51.6	173.3	176.6	-114.1	0	0	0	111.6	L466 V467 R468 D472 T473 L474 I481	L466-F470 WeakPolarHBondContact O-CB 3.46Å; V467-F470 WeakPolarHBondContact O-CB 3.12Å; V467-F470 PolarHBondContact O-N 3.49Å; R468-F470 PolarHBondContact O-N 2.83Å; F470-D472 VanDerWaalsContact C-N 3.34Å; F470-D472 PolarHBondContact O-N 3.34Å; F470-T473 WeakPolarHBondContact O-CB 3.36Å; F470-T473 PolarHBondContact O-N 2.7Å; F470-T473 VanDerWaalsContact O-N 3.15Å; F470-L474 HydrophobicContact CD1-CD1 3.73Å; F470-L474 HydrophobicContact CD2-CD1 3.71Å; F470-L474 HydrophobicContact CE1-CD1 3.49Å; F470-L474 VanDerWaalsContact CE1-CD1 3.49Å; F470-L474 HydrophobicContact CE2-CD1 3.47Å; F470-L474 VanDerWaalsContact CE2-CD1 3.47Å; F470-L474 HydrophobicContact CG-CD1 3.84Å; F470-L474 HydrophobicContact CZ-CD1 3.37Å; F470-L474 WeakPolarHBondContact O-CD1 3.49Å; F470-L474 PolarHBondContact O-N 3.3Å; F470-I481 HydrophobicContact CE1-CD1 4.08Å
471	M	90	Very high	91.6	Very high	48 Å²	48	88.5 Å²	88.5	24%	0.236	46%	0.46	C	S	.	.	H	α-helix	trans	-60.5	-40.5	177	-72.5	-64.1	100.3	0	0	112.4	V467 R468 T473 L474 A475 I481	V467-M471 HydrophobicContact CG1-CG 3.78Å; V467-M471 WeakPolarHBondContact O-CB 3.38Å; V467-M471 VanDerWaalsContact O-CG 3.24Å; V467-M471 WeakPolarHBondContact O-CG 3.44Å; V467-M471 PolarHBondContact O-N 2.81Å; R468-M471 PolarHBondContact O-N 3.42Å; R468-M471 VanDerWaalsContact O-N 3.16Å; M471-T473 VanDerWaalsContact C-N 3.29Å; M471-T473 PolarHBondContact O-N 2.8Å; M471-L474 HydrophobicContact CE-CD1 3.77Å; M471-L474 PolarHBondContact O-N 3.23Å; M471-A475 VanDerWaalsContact O-CB 3.27Å; M471-A475 WeakPolarHBondContact O-CB 3.27Å; M471-A475 PolarHBondContact O-N 3.08Å; M471-I481 HydrophobicContact CE-CD1 3.62Å; M471-I481 HydrophobicContact CE-CG1 4.25Å
472	D	90.1	Very high	91.5	Very high	70 Å²	70	88.6 Å²	88.6	37%	0.374	46%	0.464	S	S	.	.	H	α-helix	trans	-63	-38.4	176.8	-69.4	-13.6	0	0	0	110.8	R468 F470 S476	R468-D472 IonicContact NE-OD2 2.69Å; R468-D472 WeakPolarHBondContact O-CB 3.4Å; R468-D472 VanDerWaalsContact O-CG 3.24Å; R468-D472 PolarHBondContact O-N 3.36Å; F470-D472 VanDerWaalsContact C-N 3.34Å; F470-D472 PolarHBondContact O-N 3.34Å; D472-S476 WeakPolarHBondContact O-CB 3.49Å; D472-S476 PolarHBondContact O-N 3.43Å
473	T	92.1	Very high	91.4	Very high	79 Å²	79	90.6 Å²	90.6	49%	0.485	47%	0.47	S	S	.	.	H	α-helix	trans	-65.5	-47.2	175	-56.2	0	0	0	0	111.2	P469 F470 M471 S476 H477	P469-T473 WeakPolarHBondContact O-CB 3.47Å; P469-T473 PolarHBondContact O-N 3.07Å; P469-T473 VanDerWaalsContact O-N 3.12Å; P469-T473 PolarHBondContact O-OG1 3.4Å; F470-T473 WeakPolarHBondContact O-CB 3.36Å; F470-T473 PolarHBondContact O-N 2.7Å; F470-T473 VanDerWaalsContact O-N 3.15Å; M471-T473 VanDerWaalsContact C-N 3.29Å; M471-T473 PolarHBondContact O-N 2.8Å; T473-S476 PolarHBondContact O-N 2.76Å; T473-S476 PolarHBondContact O-OG 3.15Å; T473-H477 PolarHBondContact O-CD2 2.93Å; T473-H477 VanDerWaalsContact O-CD2 3.3Å; T473-H477 PolarHBondContact O-N 3.33Å
474	L	92.9	Very high	91.4	Very high	22 Å²	22	95.1 Å²	95.1	12%	0.115	49%	0.494	C	S	.	.	H	α-helix	trans	-60.3	-46.6	175.8	-86.5	111.5	0	0	0	112.2	F470 M471 S476 H477 Q478 L479 I481	F470-L474 HydrophobicContact CD1-CD1 3.73Å; F470-L474 HydrophobicContact CD2-CD1 3.71Å; F470-L474 HydrophobicContact CE1-CD1 3.49Å; F470-L474 VanDerWaalsContact CE1-CD1 3.49Å; F470-L474 HydrophobicContact CE2-CD1 3.47Å; F470-L474 VanDerWaalsContact CE2-CD1 3.47Å; F470-L474 HydrophobicContact CG-CD1 3.84Å; F470-L474 HydrophobicContact CZ-CD1 3.37Å; F470-L474 WeakPolarHBondContact O-CD1 3.49Å; F470-L474 PolarHBondContact O-N 3.3Å; M471-L474 HydrophobicContact CE-CD1 3.77Å; M471-L474 PolarHBondContact O-N 3.23Å; L474-S476 VanDerWaalsContact C-N 3.3Å; L474-S476 PolarHBondContact O-N 3.12Å; L474-H477 CarbonylContact O-C 3.41Å; L474-H477 PolarHBondContact O-N 2.83Å; L474-H477 VanDerWaalsContact O-N 3.08Å; L474-Q478 PolarHBondContact O-N 3.21Å; L474-L479 HydrophobicContact CD2-CB 4.03Å; L474-L479 WeakPolarHBondContact CD2-O 3.4Å; L474-L479 HydrophobicContact CG-CB 4.5Å; L474-L479 PolarHBondContact O-N 2.97Å; L474-I481 HydrophobicContact CD2-CG1 4.38Å; L474-I481 HydrophobicContact CD2-CG2 3.6Å
475	A	91	Very high	91.5	Very high	66 Å²	66	98.4 Å²	98.4	55%	0.545	51%	0.51	S	S	.	.	H	α-helix	trans	-61.6	-39	179.1	0	0	0	0	0	111.5	M471 H477 Q478	M471-A475 VanDerWaalsContact O-CB 3.27Å; M471-A475 WeakPolarHBondContact O-CB 3.27Å; M471-A475 PolarHBondContact O-N 3.08Å; A475-H477 PolarHBondContact O-N 3.29Å; A475-Q478 PolarHBondContact O-N 2.99Å
476	S	94.3	Very high	91.6	Very high	87 Å²	87	98.1 Å²	98.1	61%	0.608	51%	0.508	S	S	*	.	H	α-helix	trans	-63.1	-30.9	175.8	78.1	0	0	0	0	113	D472 T473 L474	D472-S476 WeakPolarHBondContact O-CB 3.49Å; D472-S476 PolarHBondContact O-N 3.43Å; T473-S476 PolarHBondContact O-N 2.76Å; T473-S476 PolarHBondContact O-OG 3.15Å; L474-S476 VanDerWaalsContact C-N 3.3Å; L474-S476 PolarHBondContact O-N 3.12Å
477	H	95.6	Very high	91.6	Very high	130 Å²	130	96.8 Å²	96.8	60%	0.602	50%	0.5	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93	1	175.2	-72.7	-65.5	0	0	0	113.6	T473 L474 A475 L479	T473-H477 PolarHBondContact O-CD2 2.93Å; T473-H477 VanDerWaalsContact O-CD2 3.3Å; T473-H477 PolarHBondContact O-N 3.33Å; L474-H477 CarbonylContact O-C 3.41Å; L474-H477 PolarHBondContact O-N 2.83Å; L474-H477 VanDerWaalsContact O-N 3.08Å; A475-H477 PolarHBondContact O-N 3.29Å; H477-L479 HydrophobicContact CB-CD1 3.97Å; H477-L479 HydrophobicContact CB-CG 3.94Å; H477-L479 PolarHBondContact O-N 2.95Å
478	Q	93.6	Very high	91.6	Very high	150 Å²	150	99.5 Å²	99.5	70%	0.701	51%	0.511	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.9	32.9	-172.8	-55.9	-173.3	-57.6	0	0	113.6	L474 A475 Y480	L474-Q478 PolarHBondContact O-N 3.21Å; A475-Q478 PolarHBondContact O-N 2.99Å; Q478-Y480 WeakPolarHBondContact O-CD2 3.15Å; Q478-Y480 WeakPolarHBondContact O-CE2 3.46Å
479	L	93.3	Very high	91.9	Very high	108 Å²	108	102.3 Å²	102.3	57%	0.565	53%	0.532	S	S	*	.			trans	-90.8	132.1	173.4	-63.8	174.4	0	0	0	108.9	L474 H477	L474-L479 HydrophobicContact CD2-CB 4.03Å; L474-L479 WeakPolarHBondContact CD2-O 3.4Å; L474-L479 HydrophobicContact CG-CB 4.5Å; L474-L479 PolarHBondContact O-N 2.97Å; H477-L479 HydrophobicContact CB-CD1 3.97Å; H477-L479 HydrophobicContact CB-CG 3.94Å; H477-L479 PolarHBondContact O-N 2.95Å
480	Y	91.2	Very high	91.9	Very high	205 Å²	205	105.4 Å²	105.4	80%	0.804	54%	0.541	S	S	*	.			trans	-114.2	141	178.9	-58.7	-83.9	0	0	0	109.5	Q478	Q478-Y480 WeakPolarHBondContact O-CD2 3.15Å; Q478-Y480 WeakPolarHBondContact O-CE2 3.46Å
481	I	88.3	Confident	92	Very high	184 Å²	184	104.5 Å²	104.5	94%	0.944	54%	0.544	S	S	*	.			trans	-118.3	0	178.2	55.5	163.5	0	0	0	112	F470 M471 L474	F470-I481 HydrophobicContact CE1-CD1 4.08Å; M471-I481 HydrophobicContact CE-CD1 3.62Å; M471-I481 HydrophobicContact CE-CG1 4.25Å; L474-I481 HydrophobicContact CD2-CG1 4.38Å; L474-I481 HydrophobicContact CD2-CG2 3.6Å

Retrieved 481 of 481 residues in 1193.3 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).