A0A096MSS6_PAPAN Loading...

Dihydropyrimidinase

AlphaFold DB , UniProt , Accession A0A096MSS6, Species PAPAN (Papio anubis, Olive baboon), Gene DPYS, Length 519 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M38.4Very low77.5Confident243 Ų24371.5 Ų71.5100%1.19743%0.425SS*.  0125.70-72.4-173.7-96.100107.1
2A48Very low79.2Confident100 Ų10065.6 Ų65.683%0.82639%0.39SS*.PPolyproline II helixtrans-62.2143.7171.900000108.6
3A52.7Low80.7Confident89 Ų8969.8 Ų69.874%0.73640%0.395SS*.PPolyproline II helixtrans-56.7141.1175.300000109.8S5A3-S5 PolarHBondContact O-N 3.41Å
4P61.2Low82Confident82 Ų8264.9 Ų64.953%0.53237%0.367SS..PPolyproline II helixtrans-57.9128.6179.921.7-31000110.2R6 D29P4-R6 PolarHBondContact O-N 3.31Å; P4-D29 WeakPolarHBondContact CB-OD1 2.96Å
5S80.1Confident83.1Confident43 Ų4360.6 Ų60.630%0.30134%0.343SS..  trans-74.7111.5175.1-175.70000108.1A3 D29 G444A3-S5 PolarHBondContact O-N 3.41Å; S5-D29 PolarHBondContact O-N 3Å; S5-G444 PolarHBondContact OG-O 2.87Å
6R92.1Very high84.1Confident79 Ų7957.1 Ų57.130%0.29832%0.323SS..EExtended strand (participates in β ladder)trans-116.8118.7176.3-60.2179.973.9-161.84.4108.8P4 V27 E28 L49 R50P4-R6 PolarHBondContact O-N 3.31Å; R6-V27 WeakPolarHBondContact CA-O 3.38Å; R6-E28 HydrophobicContact CG-CG 4.23Å; R6-E28 IonicContact CZ-OE1 3.67Å; R6-E28 IonicContact NE-OE1 3.94Å; R6-E28 PolarHBondContact NE-OE1 3.05Å; R6-E28 IonicContact NH2-OE1 2.87Å; R6-E28 PolarHBondContact NH2-OE1 3.39Å; R6-L49 HydrophobicContact CB-CD1 3.78Å; R6-R50 PolarHBondContact O-N 3.39Å; R6-R50 VanDerWaalsContact O-N 3.07Å
7L95.3Very high85Confident7 Ų755.7 Ų55.74%0.03731%0.314CS..EExtended strand (participates in β ladder)trans-121141.9176.5-53.7177.6000109.3V27 R50 I441 G444 V446L7-V27 HydrophobicContact CB-CB 4.17Å; L7-V27 PolarHBondContact N-O 3.46Å; L7-V27 PolarHBondContact O-N 3.33Å; L7-R50 CarbonylContact C-O 3.52Å; L7-R50 WeakPolarHBondContact CA-O 3.4Å; L7-R50 HydrophobicContact CD2-CB 3.74Å; L7-R50 HydrophobicContact CD2-CG 4.11Å; L7-I441 HydrophobicContact CD1-CD1 4.47Å; L7-I441 HydrophobicContact CD1-CG2 3.94Å; L7-G444 WeakPolarHBondContact CD1-O 3.4Å; L7-V446 HydrophobicContact CD1-CG2 4.09Å; L7-V446 HydrophobicContact CD2-CG2 4.47Å
8L96.5Very high85.7Confident2 Ų257.4 Ų57.41%0.0132%0.323CS..EExtended strand (participates in β ladder)trans-122.3120.9166.4-179.574.4000109.2D24 V25 L26 L39 L40 L49 R50 V51 L52L8-D24 HydrophobicContact CD1-CB 4.1Å; L8-V25 WeakPolarHBondContact CA-O 3.49Å; L8-L26 HydrophobicContact CD1-CB 4.09Å; L8-L26 HydrophobicContact CD1-CD1 4.31Å; L8-L39 HydrophobicContact CD1-CB 3.98Å; L8-L39 HydrophobicContact CD1-CD1 4.4Å; L8-L40 HydrophobicContact CD2-CB 4.49Å; L8-L40 HydrophobicContact CD2-CD1 3.96Å; L8-L40 HydrophobicContact CD2-CD2 3.61Å; L8-L40 HydrophobicContact CD2-CG 3.34Å; L8-L49 HydrophobicContact CB-CD1 4.05Å; L8-L49 HydrophobicContact CB-CD2 4.1Å; L8-L49 HydrophobicContact CB-CG 4.27Å; L8-L49 HydrophobicContact CD2-CD2 4.46Å; L8-R50 PolarHBondContact N-O 2.7Å; L8-V51 HydrophobicContact CB-CG2 4.46Å; L8-V51 CarbonylContact O-C 3.57Å; L8-V51 WeakPolarHBondContact O-CA 3.48Å; L8-L52 PolarHBondContact O-N 3.43Å
9I97.8Very high86.4Confident1 Ų159.2 Ų59.21%0.00533%0.327CS..EExtended strand (participates in β ladder)trans-92.7119.1170.1-52171.2000106.9D24 V25 L52 A54 V59 I403 I405 I441I9-D24 CarbonylContact O-C 3.6Å; I9-D24 WeakPolarHBondContact O-CA 3.47Å; I9-D24 WeakPolarHBondContact O-CB 3.28Å; I9-V25 HydrophobicContact CB-CB 4.18Å; I9-V25 HydrophobicContact CD1-CB 4.3Å; I9-V25 PolarHBondContact N-O 2.84Å; I9-V25 PolarHBondContact O-N 3.03Å; I9-L52 HydrophobicContact CG1-CD1 4.32Å; I9-A54 HydrophobicContact CG2-CB 3.62Å; I9-V59 HydrophobicContact CD1-CG1 4.06Å; I9-V59 HydrophobicContact CG2-CG1 4.17Å; I9-V59 HydrophobicContact CG2-CG2 3.81Å; I9-I403 HydrophobicContact CD1-CB 4.26Å; I9-I403 HydrophobicContact CD1-CD1 3.94Å; I9-I403 HydrophobicContact CD1-CG2 3.62Å; I9-I405 HydrophobicContact CG2-CD1 3.91Å; I9-I405 HydrophobicContact CG2-CG1 4.17Å; I9-I441 HydrophobicContact CD1-CD1 3.54Å; I9-I441 HydrophobicContact CG1-CD1 4.04Å
10R96.1Very high87Confident110 Ų11058 Ų5842%0.41532%0.323SS..EExtended strand (participates in β ladder)trans-114.2137.3-169.5-169.5-173.1-178.7-176.9-1.5112.6G12 D24 V51 L52 A54R10-G12 PolarHBondContact O-N 3.11Å; R10-D24 VanDerWaalsContact CA-OD1 3.28Å; R10-D24 WeakPolarHBondContact CA-OD1 3.3Å; R10-D24 WeakPolarHBondContact CG-OD1 3.45Å; R10-V51 HydrophobicContact CB-CG1 4.17Å; R10-L52 PolarHBondContact N-O 3.09Å; R10-A54 WeakPolarHBondContact O-CA 3.06Å; R10-A54 PolarHBondContact O-N 3.43Å
11G94.8Very high87.5Confident31 Ų3158.8 Ų58.832%0.3232%0.324SS..SBendtrans73.77.1165.400000115.7D24G11-D24 PolarHBondContact N-OD1 3.27Å
12G97.7Very high90.4Very high0 Ų050.5 Ų50.50%029%0.287CS..  trans-80.8163.3177.900000113.4R10 V22 A23 A54R10-G12 PolarHBondContact O-N 3.11Å; G12-V22 WeakPolarHBondContact O-CA 3.26Å; G12-A23 PolarHBondContact O-N 2.85Å; G12-A54 WeakPolarHBondContact CA-O 3.46Å
13R98.7Very high92.7Very high120 Ų12045.8 Ų45.845%0.45325%0.248SC..EExtended strand (participates in β ladder)trans-89.3107.1166.3-178.3-179.4-65.5-152.8-2.4108.7V15 E21 K57 L58 V59 E371R13-V15 HydrophobicContact CG-CG2 4.17Å; R13-V15 PolarHBondContact O-N 3.31Å; R13-E21 CarbonylContact C-O 3.54Å; R13-E21 WeakPolarHBondContact CA-O 3.25Å; R13-K57 PolarHBondContact N-O 3.02Å; R13-L58 HydrophobicContact CB-CD2 3.98Å; R13-L58 HydrophobicContact CG-CD2 4.27Å; R13-L58 CarbonylContact O-C 3.59Å; R13-L58 WeakPolarHBondContact O-CA 3.37Å; R13-V59 PolarHBondContact O-N 2.92Å; R13-E371 IonicContact NH1-OE1 3.93Å
14V98.9Very high94.9Very high2 Ų241.9 Ų41.91%0.01222%0.215CC..EExtended strand (participates in β ladder)trans-70.4126171.2176.30000108.4S20 E21 A23 V25 L35 V59 I395V14-S20 CarbonylContact O-C 3.56Å; V14-S20 VanDerWaalsContact O-CA 3.27Å; V14-S20 WeakPolarHBondContact O-CA 3.35Å; V14-E21 PolarHBondContact N-O 3.44Å; V14-E21 PolarHBondContact O-N 3.47Å; V14-A23 HydrophobicContact CG2-CB 4.23Å; V14-V25 HydrophobicContact CG2-CG2 3.67Å; V14-L35 HydrophobicContact CB-CD1 4.49Å; V14-L35 HydrophobicContact CG1-CD1 4.36Å; V14-L35 HydrophobicContact CG2-CD1 3.89Å; V14-V59 WeakPolarHBondContact CA-O 3.41Å; V14-V59 HydrophobicContact CG2-CB 4.11Å; V14-V59 HydrophobicContact CG2-CG1 4.47Å; V14-I395 HydrophobicContact CG1-CB 3.85Å; V14-I395 HydrophobicContact CG1-CD1 3.94Å; V14-I395 HydrophobicContact CG1-CG2 3.79Å
15V98.9Very high96.6Very high0 Ų038 Ų380%019%0.19CC..EExtended strand (participates in β ladder)trans-121115.8-179.3-178.10000107.8R13 L58 V59 L60 P61 E371 V375R13-V15 HydrophobicContact CG-CG2 4.17Å; R13-V15 PolarHBondContact O-N 3.31Å; V15-L58 HydrophobicContact CG2-CB 4.2Å; V15-L58 HydrophobicContact CG2-CD1 4.42Å; V15-L58 HydrophobicContact CG2-CD2 4.05Å; V15-L58 HydrophobicContact CG2-CG 4.45Å; V15-V59 PolarHBondContact N-O 3.35Å; V15-L60 HydrophobicContact CB-CD2 3.5Å; V15-L60 HydrophobicContact CG1-CD2 4.14Å; V15-L60 HydrophobicContact CG2-CD2 3.8Å; V15-P61 VanDerWaalsContact O-CD 3.28Å; V15-P61 WeakPolarHBondContact O-CD 3.47Å; V15-E371 HydrophobicContact CB-CG 4.44Å; V15-E371 HydrophobicContact CG1-CB 3.94Å; V15-E371 HydrophobicContact CG1-CG 3.53Å; V15-E371 HydrophobicContact CG2-CG 4.01Å; V15-V375 HydrophobicContact CB-CG2 4.34Å; V15-V375 HydrophobicContact CG1-CG2 3.83Å
16N98.9Very high97.4Very high4 Ų437.4 Ų37.42%0.02118%0.183CC..  trans-105.4-179.4167.5-76.3-51.3000109.8D18 F19 N372 R394 I395N16-D18 WeakPolarHBondContact CB-OD1 3.23Å; N16-D18 PolarHBondContact O-N 2.93Å; N16-F19 PolarHBondContact N-O 3.12Å; N16-N372 WeakPolarHBondContact O-CA 3.39Å; N16-N372 PolarHBondContact O-ND2 3.35Å; N16-R394 WeakPolarHBondContact OD1-CA 3.46Å; N16-R394 WeakPolarHBondContact OD1-CG 3.31Å; N16-I395 PolarHBondContact ND2-O 3.18Å; N16-I395 PolarHBondContact OD1-N 3.11Å
17D98.8Very high97.7Very high34 Ų3433.6 Ų33.618%0.18217%0.169CC..SBendtrans-67.3-20.9178.563.1-50.9000114.1N372 A376 T380 K384 R394D17-N372 WeakPolarHBondContact CA-O 3.42Å; D17-A376 HydrophobicContact CB-CB 3.89Å; D17-T380 HydrophobicContact CB-CG2 4.09Å; D17-T380 WeakPolarHBondContact OD2-CG2 3.01Å; D17-K384 IonicContact OD2-NZ 3.4Å; D17-K384 PolarHBondContact OD2-NZ 3.1Å; D17-R394 IonicContact OD1-NH1 3.02Å; D17-R394 PolarHBondContact OD1-NH1 3.39Å
18D98.5Very high97.7Very high87 Ų8735.5 Ų35.547%0.46518%0.177SC..SBendtrans-101.9-39.7-173.254.9-29.3000114.2N16 R394N16-D18 WeakPolarHBondContact CB-OD1 3.23Å; N16-D18 PolarHBondContact O-N 2.93Å; D18-R394 VanDerWaalsContact CG-NH1 3.33Å; D18-R394 IonicContact OD1-CZ 3.03Å; D18-R394 IonicContact OD1-NH1 3.8Å; D18-R394 PolarHBondContact OD1-NH1 3.07Å; D18-R394 IonicContact OD1-NH2 3.65Å; D18-R394 PolarHBondContact OD1-NH2 3.16Å; D18-R394 IonicContact OD2-CZ 3.26Å; D18-R394 IonicContact OD2-NH1 3.87Å; D18-R394 PolarHBondContact OD2-NH1 2.86Å; D18-R394 IonicContact OD2-NH2 3.17Å; D18-R394 PolarHBondContact OD2-NH2 3.45Å
19F97.9Very high97.5Very high91 Ų9140.3 Ų40.340%0.39920%0.203SC..  trans-158.317017672-81.7000112.6N16 E21 N372N16-F19 PolarHBondContact N-O 3.12Å; F19-E21 HydrophobicContact CD2-CB 4.27Å; F19-E21 HydrophobicContact CE2-CB 3.97Å; F19-E21 HydrophobicContact CE2-CG 3.83Å; F19-N372 PolarHBondContact O-ND2 3.06Å
20S98.6Very high97.4Very high35 Ų3540.9 Ų40.925%0.24521%0.209CC..EExtended strand (participates in β ladder)trans-120.9135.6177.3-58.70000111V14 N372V14-S20 CarbonylContact O-C 3.56Å; V14-S20 VanDerWaalsContact O-CA 3.27Å; V14-S20 WeakPolarHBondContact O-CA 3.35Å; S20-N372 PolarHBondContact OG-ND2 3.29Å; S20-N372 PolarHBondContact OG-OD1 2.8Å
21E98.1Very high97.5Very high74 Ų7437.1 Ų37.135%0.34620%0.198SC..EExtended strand (participates in β ladder)trans-142.3154.4177.168.1178.3148.600112.7R13 V14 F19 A23R13-E21 CarbonylContact C-O 3.54Å; R13-E21 WeakPolarHBondContact CA-O 3.25Å; V14-E21 PolarHBondContact N-O 3.44Å; V14-E21 PolarHBondContact O-N 3.47Å; F19-E21 HydrophobicContact CD2-CB 4.27Å; F19-E21 HydrophobicContact CE2-CB 3.97Å; F19-E21 HydrophobicContact CE2-CG 3.83Å; E21-A23 HydrophobicContact CG-CB 4.25Å
22V98.2Very high97.7Very high69 Ų6935.7 Ų35.742%0.41818%0.183SC..EExtended strand (participates in β ladder)trans-85115170.2178.20000108.6G12 R37G12-V22 WeakPolarHBondContact O-CA 3.26Å; V22-R37 PolarHBondContact O-NE 3.43Å
23A97.8Very high97.6Very high2 Ų241.6 Ų41.62%0.01721%0.205CC..  trans-153.8150-178.500000110.8G12 V14 E21 L35G12-A23 PolarHBondContact O-N 2.85Å; V14-A23 HydrophobicContact CG2-CB 4.23Å; E21-A23 HydrophobicContact CG-CB 4.25Å; A23-L35 HydrophobicContact CB-CD1 3.72Å; A23-L35 HydrophobicContact CB-CG 4.18Å
24D97.8Very high97.5Very high7 Ų737.1 Ų37.14%0.03719%0.194CC..EExtended strand (participates in β ladder)trans-82.4149.7165-57.6-22000109.7L8 I9 R10 G11 L35 G36 D38 L39L8-D24 HydrophobicContact CD1-CB 4.1Å; I9-D24 CarbonylContact O-C 3.6Å; I9-D24 WeakPolarHBondContact O-CA 3.47Å; I9-D24 WeakPolarHBondContact O-CB 3.28Å; R10-D24 VanDerWaalsContact CA-OD1 3.28Å; R10-D24 WeakPolarHBondContact CA-OD1 3.3Å; R10-D24 WeakPolarHBondContact CG-OD1 3.45Å; G11-D24 PolarHBondContact N-OD1 3.27Å; D24-L35 WeakPolarHBondContact O-CA 3.5Å; D24-G36 WeakPolarHBondContact CA-O 3.36Å; D24-G36 WeakPolarHBondContact CB-O 3.5Å; D24-G36 PolarHBondContact N-O 3.12Å; D24-G36 PolarHBondContact O-N 3.31Å; D24-G36 VanDerWaalsContact O-N 3.16Å; D24-D38 WeakPolarHBondContact OD2-CA 3.37Å; D24-D38 PolarHBondContact OD2-N 3.16Å; D24-L39 HydrophobicContact CB-CB 4.02Å; D24-L39 HydrophobicContact CB-CD1 3.91Å; D24-L39 HydrophobicContact CB-CG 3.93Å; D24-L39 WeakPolarHBondContact O-CD1 3.42Å; D24-L39 PolarHBondContact OD2-N 3.49Å
25V98.2Very high97.4Very high0 Ų039.5 Ų39.50%021%0.206CC..EExtended strand (participates in β ladder)trans-121.5111178.1-1690000109.3L8 I9 V14 V27 V32 L35 V59 I395 I403L8-V25 WeakPolarHBondContact CA-O 3.49Å; I9-V25 HydrophobicContact CB-CB 4.18Å; I9-V25 HydrophobicContact CD1-CB 4.3Å; I9-V25 PolarHBondContact N-O 2.84Å; I9-V25 PolarHBondContact O-N 3.03Å; V14-V25 HydrophobicContact CG2-CG2 3.67Å; V25-V27 HydrophobicContact CG1-CG2 4.3Å; V25-V32 HydrophobicContact CG1-CG1 3.77Å; V25-V32 HydrophobicContact CG1-CG2 4.05Å; V25-L35 HydrophobicContact CG2-CD1 3.84Å; V25-V59 HydrophobicContact CG2-CG1 4.27Å; V25-I395 HydrophobicContact CG1-CG2 4.11Å; V25-I395 HydrophobicContact CG2-CG2 4.03Å; V25-I403 HydrophobicContact CG1-CD1 3.98Å
26L97.2Very high97.3Very high30 Ų3040.5 Ų40.516%0.15722%0.217CC..EExtended strand (participates in β ladder)trans-88.6124.6172.6179.766.5000109.6L8 E28 R33 A34 L39 L49L8-L26 HydrophobicContact CD1-CB 4.09Å; L8-L26 HydrophobicContact CD1-CD1 4.31Å; L26-E28 HydrophobicContact CD1-CG 4.37Å; L26-E28 HydrophobicContact CD2-CG 4.49Å; L26-E28 HydrophobicContact CG-CG 4.19Å; L26-R33 HydrophobicContact CD2-CB 4.44Å; L26-R33 HydrophobicContact CG-CB 4.48Å; L26-R33 PolarHBondContact O-N 3.06Å; L26-A34 HydrophobicContact CB-CB 4.03Å; L26-A34 HydrophobicContact CD2-CB 4.3Å; L26-A34 PolarHBondContact N-O 3.33Å; L26-A34 PolarHBondContact O-N 2.9Å; L26-L39 HydrophobicContact CB-CD1 4.12Å; L26-L49 HydrophobicContact CD1-CD1 4.09Å
27V96.9Very high97Very high0 Ų049.1 Ų49.10%025%0.249CC..EExtended strand (participates in β ladder)trans-115.3128.9177.3172.10000109.1R6 L7 V25 V31 V32 A401 I403R6-V27 WeakPolarHBondContact CA-O 3.38Å; L7-V27 HydrophobicContact CB-CB 4.17Å; L7-V27 PolarHBondContact N-O 3.46Å; L7-V27 PolarHBondContact O-N 3.33Å; V25-V27 HydrophobicContact CG1-CG2 4.3Å; V27-V31 WeakPolarHBondContact CA-O 3.36Å; V27-V32 HydrophobicContact CG2-CG2 4.45Å; V27-A401 HydrophobicContact CB-CB 4.14Å; V27-A401 HydrophobicContact CG1-CB 3.31Å; V27-A401 HydrophobicContact CG2-CB 3.69Å; V27-I403 HydrophobicContact CG2-CD1 4.12Å
28E95.1Very high96.6Very high47 Ų4753.2 Ų53.222%0.2227%0.271CS..EExtended strand (participates in β ladder)trans-137.8131.5172.5-48.6-176.7138.300109.6R6 L26 G30 V31 R33R6-E28 HydrophobicContact CG-CG 4.23Å; R6-E28 IonicContact CZ-OE1 3.67Å; R6-E28 IonicContact NE-OE1 3.94Å; R6-E28 PolarHBondContact NE-OE1 3.05Å; R6-E28 IonicContact NH2-OE1 2.87Å; R6-E28 PolarHBondContact NH2-OE1 3.39Å; L26-E28 HydrophobicContact CD1-CG 4.37Å; L26-E28 HydrophobicContact CD2-CG 4.49Å; L26-E28 HydrophobicContact CG-CG 4.19Å; E28-G30 PolarHBondContact O-N 3.01Å; E28-V31 PolarHBondContact N-O 3.11Å; E28-V31 PolarHBondContact O-N 2.98Å; E28-R33 HydrophobicContact CB-CG 3.62Å; E28-R33 HydrophobicContact CG-CB 4.37Å; E28-R33 HydrophobicContact CG-CG 3.79Å; E28-R33 PolarHBondContact O-NE 3.34Å
29D93Very high96.2Very high103 Ų10351.8 Ų51.855%0.55126%0.263SS*.THydrogen-bonded Turntrans54.839.2178-55.7-41.8000113.5P4 S5 V31P4-D29 WeakPolarHBondContact CB-OD1 2.96Å; S5-D29 PolarHBondContact O-N 3Å; D29-V31 VanDerWaalsContact C-N 3.33Å; D29-V31 PolarHBondContact O-N 3.18Å
30G95.6Very high95.5Very high12 Ų1248.9 Ų48.912%0.12425%0.252CS..THydrogen-bonded Turntrans80.59.2176.300000115.4E28 A401 R443E28-G30 PolarHBondContact O-N 3.01Å; G30-A401 WeakPolarHBondContact O-CB 3.48Å; G30-A401 PolarHBondContact O-N 3.45Å; G30-R443 VanDerWaalsContact CA-O 3.25Å; G30-R443 WeakPolarHBondContact CA-O 3.45Å
31V98.1Very high94Very high32 Ų3250.3 Ų50.319%0.19426%0.26CS..EExtended strand (participates in β ladder)trans-128.2143.3-177.1179.80000110.1V27 E28 D29 R33 S399V27-V31 WeakPolarHBondContact CA-O 3.36Å; E28-V31 PolarHBondContact N-O 3.11Å; E28-V31 PolarHBondContact O-N 2.98Å; D29-V31 VanDerWaalsContact C-N 3.33Å; D29-V31 PolarHBondContact O-N 3.18Å; V31-R33 PolarHBondContact O-N 3.21Å; V31-S399 WeakPolarHBondContact CA-O 3.45Å; V31-S399 WeakPolarHBondContact CG1-O 3.37Å
32V98.3Very high92.1Very high1 Ų153.6 Ų53.61%0.00629%0.288CS..EExtended strand (participates in β ladder)trans-69.2115.7169.9177.10000109.1V25 V27 A396 V397 G398 S399 A401 I403V25-V32 HydrophobicContact CG1-CG1 3.77Å; V25-V32 HydrophobicContact CG1-CG2 4.05Å; V27-V32 HydrophobicContact CG2-CG2 4.45Å; V32-A396 VanDerWaalsContact CB-O 3.31Å; V32-A396 WeakPolarHBondContact CB-O 3.38Å; V32-V397 WeakPolarHBondContact O-CA 3.38Å; V32-G398 PolarHBondContact O-N 3.24Å; V32-S399 PolarHBondContact N-O 3.45Å; V32-A401 HydrophobicContact CG2-CB 4.42Å; V32-I403 HydrophobicContact CG2-CD1 4Å
33R97.2Very high90.6Very high123 Ų12354.7 Ų54.746%0.46431%0.313SS..EExtended strand (participates in β ladder)trans-97.8-34.9-176.9-66.6-53.6-174.2165.22.6113.9L26 E28 V31L26-R33 HydrophobicContact CD2-CB 4.44Å; L26-R33 HydrophobicContact CG-CB 4.48Å; L26-R33 PolarHBondContact O-N 3.06Å; E28-R33 HydrophobicContact CB-CG 3.62Å; E28-R33 HydrophobicContact CG-CB 4.37Å; E28-R33 HydrophobicContact CG-CG 3.79Å; E28-R33 PolarHBondContact O-NE 3.34Å; V31-R33 PolarHBondContact O-N 3.21Å
34A96.6Very high89.3Confident27 Ų2756.7 Ų56.722%0.22333%0.334CS..EExtended strand (participates in β ladder)trans-146147.5176.800000110.5L26 L39L26-A34 HydrophobicContact CB-CB 4.03Å; L26-A34 HydrophobicContact CD2-CB 4.3Å; L26-A34 PolarHBondContact N-O 3.33Å; L26-A34 PolarHBondContact O-N 2.9Å; A34-L39 HydrophobicContact CB-CD1 3.91Å; A34-L39 HydrophobicContact CB-CD2 4.34Å
35L97Very high88.3Confident51 Ų5158.8 Ų58.827%0.26735%0.353SS..EExtended strand (participates in β ladder)trans-133.9125.5174.7-18071000106.5V14 A23 D24 V25 I395V14-L35 HydrophobicContact CB-CD1 4.49Å; V14-L35 HydrophobicContact CG1-CD1 4.36Å; V14-L35 HydrophobicContact CG2-CD1 3.89Å; A23-L35 HydrophobicContact CB-CD1 3.72Å; A23-L35 HydrophobicContact CB-CG 4.18Å; D24-L35 WeakPolarHBondContact O-CA 3.5Å; V25-L35 HydrophobicContact CG2-CD1 3.84Å; L35-I395 HydrophobicContact CD1-CG2 4.3Å
36G95.4Very high87.4Confident22 Ų2261.1 Ų61.123%0.22737%0.368CS..EExtended strand (participates in β ladder)trans168.1177.6-177.400000112.3D24D24-G36 WeakPolarHBondContact CA-O 3.36Å; D24-G36 WeakPolarHBondContact CB-O 3.5Å; D24-G36 PolarHBondContact N-O 3.12Å; D24-G36 PolarHBondContact O-N 3.31Å; D24-G36 VanDerWaalsContact O-N 3.16Å
37R93.5Very high86.5Confident185 Ų18567 Ų6770%0.69840%0.404SS*.SBendtrans-85.4146.5177.5-65.1-176.5179.4178.62.8111V22 L39V22-R37 PolarHBondContact O-NE 3.43Å; R37-L39 VanDerWaalsContact C-N 3.35Å; R37-L39 PolarHBondContact O-N 3.36Å
38D89.2Confident85.8Confident120 Ų12069.9 Ų69.964%0.64244%0.435SS*.  trans53.848.6170.6-57-57.7000112.7D24 L40D24-D38 WeakPolarHBondContact OD2-CA 3.37Å; D24-D38 PolarHBondContact OD2-N 3.16Å; D38-L40 PolarHBondContact O-N 3.42Å
39L90.9Very high85.5Confident56 Ų5668.7 Ų68.729%0.29343%0.429SS..  trans-72.3-8-178.2-67.7-177.1000113.4L8 D24 L26 A34 R37L8-L39 HydrophobicContact CD1-CB 3.98Å; L8-L39 HydrophobicContact CD1-CD1 4.4Å; D24-L39 HydrophobicContact CB-CB 4.02Å; D24-L39 HydrophobicContact CB-CD1 3.91Å; D24-L39 HydrophobicContact CB-CG 3.93Å; D24-L39 WeakPolarHBondContact O-CD1 3.42Å; D24-L39 PolarHBondContact OD2-N 3.49Å; L26-L39 HydrophobicContact CB-CD1 4.12Å; A34-L39 HydrophobicContact CB-CD1 3.91Å; A34-L39 HydrophobicContact CB-CD2 4.34Å; R37-L39 VanDerWaalsContact C-N 3.35Å; R37-L39 PolarHBondContact O-N 3.36Å
40L82.9Confident85.5Confident31 Ų3168.3 Ų68.316%0.16242%0.42CS..SBendtrans-73.1128168.5-81.3166000110.2L8 D38 A45 L49 V51L8-L40 HydrophobicContact CD2-CB 4.49Å; L8-L40 HydrophobicContact CD2-CD1 3.96Å; L8-L40 HydrophobicContact CD2-CD2 3.61Å; L8-L40 HydrophobicContact CD2-CG 3.34Å; D38-L40 PolarHBondContact O-N 3.42Å; L40-A45 HydrophobicContact CD2-CB 4.02Å; L40-L49 HydrophobicContact CD2-CD2 3.94Å; L40-V51 HydrophobicContact CD2-CG2 4.26Å
41P66.5Low85.5Confident65 Ų6570.4 Ų70.442%0.42243%0.431SS..PPolyproline II helixtrans-62.5148.9171.614.6-15.7000111.2G43 G44 P46P41-G43 PolarHBondContact O-N 3.38Å; P41-G44 PolarHBondContact O-N 3.49Å; P41-P46 HydrophobicContact CG-CG 4.31Å
42P59.2Low85.4Confident142 Ų14269.3 Ų69.392%0.92242%0.424SS*.THydrogen-bonded Turntrans-55.8124.5169.3-20.430.8000110
43G67.4Low85.2Confident92 Ų9275.2 Ų75.295%0.94846%0.455SS*.THydrogen-bonded Turntrans115.5-2.8-178.400000116P41P41-G43 PolarHBondContact O-N 3.38Å
44G70Confident85.3Confident44 Ų4469.3 Ų69.345%0.45443%0.433SS..SBendtrans106.9176.8172.900000114.1P41P41-G44 PolarHBondContact O-N 3.49Å
45A76.6Confident85.2Confident52 Ų5270.4 Ų70.443%0.4344%0.442SS..PPolyproline II helixtrans-68.6129.9-178.500000110.9L40 L49 V51L40-A45 HydrophobicContact CD2-CB 4.02Å; A45-L49 HydrophobicContact CB-CD2 4.28Å; A45-V51 HydrophobicContact CB-CG2 3.84Å
46P79.2Confident85.2Confident49 Ų4971.3 Ų71.332%0.31846%0.463SS..PPolyproline II helixtrans-54.8149.2170.9-24.333.1000111.8P41 G48 L49P41-P46 HydrophobicContact CG-CG 4.31Å; P46-G48 PolarHBondContact O-N 2.96Å; P46-L49 WeakPolarHBondContact O-CB 3.41Å; P46-L49 PolarHBondContact O-N 2.74Å
47V78.3Confident85.4Confident152 Ų15272.8 Ų72.892%0.92146%0.463SS*.THydrogen-bonded Turntrans-54.1128.4174.4178.70000109.7
48G81.4Confident85.6Confident62 Ų6264.7 Ų64.764%0.63943%0.434SS*.THydrogen-bonded Turntrans87.5-2.2-179.100000115.6P46P46-G48 PolarHBondContact O-N 2.96Å
49L89.6Confident86.1Confident21 Ų2159 Ų5911%0.1140%0.403CS..EExtended strand (participates in β ladder)trans-86.3115.7169.3-178.167.6000110R6 L8 L26 L40 A45 P46 V51R6-L49 HydrophobicContact CB-CD1 3.78Å; L8-L49 HydrophobicContact CB-CD1 4.05Å; L8-L49 HydrophobicContact CB-CD2 4.1Å; L8-L49 HydrophobicContact CB-CG 4.27Å; L8-L49 HydrophobicContact CD2-CD2 4.46Å; L26-L49 HydrophobicContact CD1-CD1 4.09Å; L40-L49 HydrophobicContact CD2-CD2 3.94Å; A45-L49 HydrophobicContact CB-CD2 4.28Å; P46-L49 WeakPolarHBondContact O-CB 3.41Å; P46-L49 PolarHBondContact O-N 2.74Å; L49-V51 HydrophobicContact CD2-CG2 4.34Å; L49-V51 HydrophobicContact CG-CG2 4.37Å
50R93.1Very high86.5Confident96 Ų9656.3 Ų56.336%0.36239%0.389SS..EExtended strand (participates in β ladder)trans-84.3123.9169.4176.2178.2176.2177-0.6109.3R6 L7 L8 L52 E449R6-R50 PolarHBondContact O-N 3.39Å; R6-R50 VanDerWaalsContact O-N 3.07Å; L7-R50 CarbonylContact C-O 3.52Å; L7-R50 WeakPolarHBondContact CA-O 3.4Å; L7-R50 HydrophobicContact CD2-CB 3.74Å; L7-R50 HydrophobicContact CD2-CG 4.11Å; L8-R50 PolarHBondContact N-O 2.7Å; R50-L52 HydrophobicContact CG-CD2 4.43Å; R50-E449 IonicContact CZ-OE2 2.83Å; R50-E449 IonicContact NH2-OE1 2.77Å; R50-E449 PolarHBondContact NH2-OE1 3.17Å; R50-E449 IonicContact NH2-OE2 2.68Å; R50-E449 PolarHBondContact NH2-OE2 2.94Å
51V94.3Very high87.2Confident56 Ų5655 Ų5534%0.33938%0.383SS..EExtended strand (participates in β ladder)trans-99.7128.6176.6-175.80000109.3L8 R10 L40 A45 L49L8-V51 HydrophobicContact CB-CG2 4.46Å; L8-V51 CarbonylContact O-C 3.57Å; L8-V51 WeakPolarHBondContact O-CA 3.48Å; R10-V51 HydrophobicContact CB-CG1 4.17Å; L40-V51 HydrophobicContact CD2-CG2 4.26Å; A45-V51 HydrophobicContact CB-CG2 3.84Å; L49-V51 HydrophobicContact CD2-CG2 4.34Å; L49-V51 HydrophobicContact CG-CG2 4.37Å
52L96Very high88.8Confident9 Ų952 Ų525%0.04736%0.363CS..EExtended strand (participates in β ladder)trans-108.2120173.6-60.1173.7000108.2L8 I9 R10 R50 A54 I405 V439 I441 V446L8-L52 PolarHBondContact O-N 3.43Å; I9-L52 HydrophobicContact CG1-CD1 4.32Å; R10-L52 PolarHBondContact N-O 3.09Å; R50-L52 HydrophobicContact CG-CD2 4.43Å; L52-A54 PolarHBondContact O-N 2.97Å; L52-I405 HydrophobicContact CB-CD1 3.85Å; L52-I405 HydrophobicContact CD1-CD1 4.1Å; L52-V439 HydrophobicContact CD1-CG1 4.32Å; L52-I441 HydrophobicContact CD1-CD1 3.7Å; L52-I441 HydrophobicContact CD1-CG1 4.39Å; L52-V446 HydrophobicContact CD1-CG2 3.75Å; L52-V446 HydrophobicContact CD2-CG2 4.26Å
53D95.7Very high90.7Very high124 Ų12445.2 Ų45.266%0.66332%0.32SS*.EExtended strand (participates in β ladder)trans-79.4116.4176.1-173.74000110.1A55D53-A55 WeakPolarHBondContact OD1-CB 3.26Å; D53-A55 PolarHBondContact OD1-N 3.39Å
54A97.7Very high92.2Very high0 Ų041 Ų410%028%0.275CS..  trans-111.916.5176.700000112I9 R10 G12 L52 G56 K57 V59 I405I9-A54 HydrophobicContact CG2-CB 3.62Å; R10-A54 WeakPolarHBondContact O-CA 3.06Å; R10-A54 PolarHBondContact O-N 3.43Å; G12-A54 WeakPolarHBondContact CA-O 3.46Å; L52-A54 PolarHBondContact O-N 2.97Å; A54-G56 PolarHBondContact O-N 3.3Å; A54-K57 HydrophobicContact CB-CB 4.44Å; A54-K57 WeakPolarHBondContact O-CA 3.25Å; A54-K57 VanDerWaalsContact O-CB 3.27Å; A54-K57 WeakPolarHBondContact O-CB 3.48Å; A54-K57 PolarHBondContact O-N 3.12Å; A54-V59 HydrophobicContact CB-CG2 3.88Å; A54-I405 HydrophobicContact CB-CD1 4.32Å; A54-I405 HydrophobicContact CB-CG2 4.04Å
55A96.3Very high93.5Very high50 Ų5038.9 Ų38.941%0.41325%0.253SS..THydrogen-bonded Turntrans-53.9126.6179.300000112.2D53 K57D53-A55 WeakPolarHBondContact OD1-CB 3.26Å; D53-A55 PolarHBondContact OD1-N 3.39Å; A55-K57 PolarHBondContact O-N 2.7Å; A55-K57 PolarHBondContact O-NZ 2.89Å
56G96.4Very high94.6Very high69 Ų6936.4 Ų36.471%0.71123%0.233SC*.THydrogen-bonded Turntrans67.211.8-177.100000114.8A54A54-G56 PolarHBondContact O-N 3.3Å
57K98.5Very high95.5Very high53 Ų5334.1 Ų34.123%0.2322%0.218CC..SBendtrans-108.1164.8174.7-50.8-60.8175.5-72.60110.5R13 A54 A55 I405 W406 D407 L438R13-K57 PolarHBondContact N-O 3.02Å; A54-K57 HydrophobicContact CB-CB 4.44Å; A54-K57 WeakPolarHBondContact O-CA 3.25Å; A54-K57 VanDerWaalsContact O-CB 3.27Å; A54-K57 WeakPolarHBondContact O-CB 3.48Å; A54-K57 PolarHBondContact O-N 3.12Å; A55-K57 PolarHBondContact O-N 2.7Å; A55-K57 PolarHBondContact O-NZ 2.89Å; K57-I405 HydrophobicContact CB-CG2 3.81Å; K57-I405 HydrophobicContact CG-CG2 4.11Å; K57-W406 WeakPolarHBondContact CB-O 3.29Å; K57-D407 HydrophobicContact CD-CB 3.78Å; K57-D407 WeakPolarHBondContact CE-OD2 3.43Å; K57-L438 HydrophobicContact CD-CD1 3.78Å; K57-L438 HydrophobicContact CG-CD1 4.24Å
58L98.9Very high96.5Very high15 Ų1526.9 Ų26.98%0.07917%0.174CC..EExtended strand (participates in β ladder)trans-93.7146.9170-49.7-177.9000109.5R13 V15 L60 W360 E371 I405 W406 P408R13-L58 HydrophobicContact CB-CD2 3.98Å; R13-L58 HydrophobicContact CG-CD2 4.27Å; R13-L58 CarbonylContact O-C 3.59Å; R13-L58 WeakPolarHBondContact O-CA 3.37Å; V15-L58 HydrophobicContact CG2-CB 4.2Å; V15-L58 HydrophobicContact CG2-CD1 4.42Å; V15-L58 HydrophobicContact CG2-CD2 4.05Å; V15-L58 HydrophobicContact CG2-CG 4.45Å; L58-L60 HydrophobicContact CB-CD2 3.73Å; L58-L60 HydrophobicContact CB-CG 4.21Å; L58-L60 HydrophobicContact CD1-CD2 4.38Å; L58-W360 HydrophobicContact CD1-CH2 3.43Å; L58-W360 VanDerWaalsContact CD1-CH2 3.43Å; L58-W360 HydrophobicContact CD1-CZ2 4.4Å; L58-W360 HydrophobicContact CD1-CZ3 3.92Å; L58-E371 HydrophobicContact CD1-CB 4.29Å; L58-I405 CarbonylContact O-C 3.54Å; L58-I405 WeakPolarHBondContact O-CA 3.26Å; L58-W406 HydrophobicContact CB-CB 4.25Å; L58-W406 PolarHBondContact N-O 3.3Å; L58-W406 PolarHBondContact O-N 2.98Å; L58-P408 HydrophobicContact CD1-CB 4.32Å; L58-P408 HydrophobicContact CD1-CG 4.41Å; L58-P408 HydrophobicContact CG-CG 4.22Å
59V98.9Very high97.3Very high0 Ų024.7 Ų24.70%015%0.147CC..EExtended strand (participates in β ladder)trans-118.6106.3174.5-1720000106I9 R13 V14 V15 V25 A54 I395 I403 V404I9-V59 HydrophobicContact CD1-CG1 4.06Å; I9-V59 HydrophobicContact CG2-CG1 4.17Å; I9-V59 HydrophobicContact CG2-CG2 3.81Å; R13-V59 PolarHBondContact O-N 2.92Å; V14-V59 WeakPolarHBondContact CA-O 3.41Å; V14-V59 HydrophobicContact CG2-CB 4.11Å; V14-V59 HydrophobicContact CG2-CG1 4.47Å; V15-V59 PolarHBondContact N-O 3.35Å; V25-V59 HydrophobicContact CG2-CG1 4.27Å; A54-V59 HydrophobicContact CB-CG2 3.88Å; V59-I395 HydrophobicContact CB-CD1 4.37Å; V59-I395 HydrophobicContact CG1-CD1 3.81Å; V59-I395 WeakPolarHBondContact O-CD1 3.43Å; V59-I403 HydrophobicContact CG1-CG2 3.38Å; V59-V404 WeakPolarHBondContact CA-O 3.32Å
60L98.9Very high97.8Very high1 Ų123.7 Ų23.71%0.00514%0.142CC..EExtended strand (participates in β ladder)trans-111.6149.8-170.6-48-176.4000110V15 L58 G62 F374 V375 I395 I403 V404 W406V15-L60 HydrophobicContact CB-CD2 3.5Å; V15-L60 HydrophobicContact CG1-CD2 4.14Å; V15-L60 HydrophobicContact CG2-CD2 3.8Å; L58-L60 HydrophobicContact CB-CD2 3.73Å; L58-L60 HydrophobicContact CB-CG 4.21Å; L58-L60 HydrophobicContact CD1-CD2 4.38Å; L60-G62 PolarHBondContact O-N 3.37Å; L60-F374 HydrophobicContact CD1-CD1 4.18Å; L60-F374 HydrophobicContact CD1-CE1 3.75Å; L60-V375 HydrophobicContact CB-CG2 4.43Å; L60-V375 HydrophobicContact CD2-CG2 3.98Å; L60-I395 VanDerWaalsContact C-CD1 3.45Å; L60-I403 WeakPolarHBondContact O-CA 3.43Å; L60-V404 PolarHBondContact N-O 2.78Å; L60-V404 PolarHBondContact O-N 3.18Å; L60-W406 HydrophobicContact CD1-CB 3.77Å; L60-W406 HydrophobicContact CD1-CD2 4.22Å; L60-W406 HydrophobicContact CD1-CG 3.85Å; L60-W406 HydrophobicContact CG-CB 4.07Å
61P98.9Very high97.9Very high3 Ų320.9 Ų20.92%0.01913%0.133CC..EExtended strand (participates in β ladder)trans-54.2138.6159.2-19.130.3000109.3V15 V375 I395V15-P61 VanDerWaalsContact O-CD 3.28Å; V15-P61 WeakPolarHBondContact O-CD 3.47Å; P61-V375 HydrophobicContact CG-CG1 3.79Å; P61-I395 HydrophobicContact CG-CG1 4.17Å
62G98.9Very high98.1Very high2 Ų218.6 Ų18.62%0.02112%0.119CC..PPolyproline II helixtrans-59144.3173.600000111.4L60 T96 S379 D402L60-G62 PolarHBondContact O-N 3.37Å; G62-T96 VanDerWaalsContact CA-OG1 3.3Å; G62-T96 WeakPolarHBondContact CA-OG1 3.25Å; G62-S379 WeakPolarHBondContact O-CB 3.49Å; G62-S379 PolarHBondContact O-OG 3.31Å; G62-D402 PolarHBondContact N-O 2.69Å
63G98.9Very high98.1Very high0 Ų020.6 Ų20.60%013%0.132CC..EExtended strand (participates in β ladder)trans-61.6144.8-179.300000111.7G94 T95 T96 M97 R355G63-G94 PolarHBondContact N-O 3.03Å; G63-T95 CarbonylContact O-C 3.55Å; G63-T95 WeakPolarHBondContact O-CA 3.45Å; G63-T95 WeakPolarHBondContact O-CG2 3.26Å; G63-T96 PolarHBondContact O-N 3.21Å; G63-M97 PolarHBondContact O-N 3.07Å; G63-R355 VanDerWaalsContact CA-NH2 3.29Å
64I99Very high98Very high2 Ų215.3 Ų15.31%0.0110%0.103CC..EExtended strand (participates in β ladder)trans-112.1112.8169.7-56.3176.8000107.1M97 I99 R355 T378 A382 A383 K392I64-M97 WeakPolarHBondContact CA-O 3.46Å; I64-M97 HydrophobicContact CG1-CB 4.23Å; I64-M97 HydrophobicContact CG2-CB 4.34Å; I64-M97 HydrophobicContact CG2-CG 4.4Å; I64-M97 HydrophobicContact CG2-SD 4.37Å; I64-I99 HydrophobicContact CG2-CD1 4.44Å; I64-I99 HydrophobicContact CG2-CG1 4.5Å; I64-R355 PolarHBondContact O-NH1 2.76Å; I64-R355 VanDerWaalsContact O-NH1 3.15Å; I64-T378 PolarHBondContact N-O 3.32Å; I64-A382 HydrophobicContact CB-CB 4.05Å; I64-A382 HydrophobicContact CG2-CB 3.95Å; I64-A383 HydrophobicContact CD1-CB 3.82Å; I64-K392 HydrophobicContact CD1-CB 3.98Å
65D98.9Very high97.6Very high0 Ų018.1 Ų18.10%012%0.117CC..EExtended strand (participates in β ladder)trans-86.8114171.9-166.8-22.8000108.9H67 T68 T95 M97 I98 I99 G324 T325D65-H67 PolarHBondContact O-N 2.99Å; D65-H67 PolarHBondContact OD1-N 3.27Å; D65-T68 HydrophobicContact CB-CG2 4.29Å; D65-T95 HydrophobicContact CB-CG2 3.88Å; D65-M97 PolarHBondContact N-O 3.12Å; D65-I98 HydrophobicContact CB-CG2 4.29Å; D65-I98 CarbonylContact O-C 3.55Å; D65-I98 WeakPolarHBondContact O-CA 3.47Å; D65-I99 PolarHBondContact O-N 3.43Å; D65-G324 WeakPolarHBondContact OD1-CA 3.3Å; D65-T325 PolarHBondContact OD1-N 3.22Å; D65-T325 PolarHBondContact OD1-OG1 3.35Å; D65-T325 WeakPolarHBondContact OD2-CB 3.28Å; D65-T325 WeakPolarHBondContact OD2-CG2 3.33Å; D65-T325 PolarHBondContact OD2-OG1 3.33Å
66T98.8Very high97.1Very high0 Ų019.9 Ų19.90%014%0.14CC..EExtended strand (participates in β ladder)trans-82.6-3.4-175.450.40000113H132 Y245 E271 T323 A382 F386T66-H132 PolarHBondContact O-NE2 2.92Å; T66-H132 VanDerWaalsContact O-NE2 3.09Å; T66-Y245 PolarHBondContact OG1-OH 2.75Å; T66-E271 WeakPolarHBondContact CB-OE2 3.48Å; T66-E271 PolarHBondContact OG1-OE2 2.86Å; T66-T323 PolarHBondContact OG1-O 2.96Å; T66-A382 HydrophobicContact CG2-CB 3.34Å; T66-F386 HydrophobicContact CG2-CD2 4.02Å; T66-F386 HydrophobicContact CG2-CE2 3.54Å
67H98.9Very high96.9Very high2 Ų218 Ų181%0.00912%0.116CC..EExtended strand (participates in β ladder)trans-148.796.6-171.2-158.8153.6000113.4D65 H69 F101 V247 H248 E271 T325 D326 N327D65-H67 PolarHBondContact O-N 2.99Å; D65-H67 PolarHBondContact OD1-N 3.27Å; H67-H69 AromaticContact CD2-CD2 3.99Å; H67-H69 AromaticContact CD2-NE2 3.34Å; H67-H69 PolarHBondContact CD2-NE2 3.35Å; H67-H69 VanDerWaalsContact CD2-NE2 3.34Å; H67-H69 AromaticContact NE2-CE1 3.85Å; H67-H69 AromaticContact NE2-NE2 3.1Å; H67-H69 PolarHBondContact NE2-NE2 2.98Å; H67-F101 HydrophobicContact CB-CE2 4.29Å; H67-F101 AromaticContact CD2-CD2 3.81Å; H67-F101 AromaticContact CD2-CE2 3.17Å; H67-F101 WeakPolarHBondContact CD2-CE2 3.46Å; H67-F101 AromaticContact CD2-CZ 3.97Å; H67-F101 AromaticContact CG-CE2 3.69Å; H67-F101 AromaticContact NE2-CE2 3.5Å; H67-F101 WeakPolarHBondContact NE2-CE2 3.36Å; H67-F101 AromaticContact NE2-CZ 3.93Å; H67-V247 VanDerWaalsContact CE1-CG2 3.47Å; H67-V247 WeakPolarHBondContact CE1-CG2 3.38Å; H67-H248 AromaticContact CE1-CD2 3.39Å; H67-H248 PolarHBondContact CE1-CD2 3.02Å; H67-E271 IonicContact CE1-OE1 2.69Å; H67-E271 IonicContact CG-OE1 2.93Å; H67-E271 IonicContact ND1-OE1 3.79Å; H67-E271 PolarHBondContact ND1-OE1 3.39Å; H67-T325 PolarHBondContact O-N 3.04Å; H67-T325 PolarHBondContact O-OG1 2.81Å; H67-D326 IonicContact CD2-OD1 3.31Å; H67-D326 PolarHBondContact CD2-OD1 3.29Å; H67-D326 IonicContact CE1-OD1 2.9Å; H67-D326 IonicContact NE2-OD1 2.63Å; H67-D326 PolarHBondContact NE2-OD1 2.86Å; H67-D326 VanDerWaalsContact O-CA 3.28Å; H67-D326 WeakPolarHBondContact O-CA 3.15Å; H67-D326 PolarHBondContact O-N 2.74Å; H67-N327 PolarHBondContact O-N 3.34Å
68T98.9Very high96.9Very high0 Ų020.2 Ų20.20%012%0.123CC..EExtended strand (participates in β ladder)trans-131.8157.3174.567.20000112.3D65 M70 I98 I99 D100 F101 N327 V352D65-T68 HydrophobicContact CB-CG2 4.29Å; T68-M70 HydrophobicContact CG2-CE 3.82Å; T68-I98 HydrophobicContact CG2-CB 3.99Å; T68-I98 HydrophobicContact CG2-CG2 4.08Å; T68-I99 PolarHBondContact N-O 3.07Å; T68-D100 WeakPolarHBondContact CB-OD2 3.36Å; T68-D100 WeakPolarHBondContact O-CA 3.46Å; T68-D100 WeakPolarHBondContact OG1-CA 3.36Å; T68-D100 WeakPolarHBondContact OG1-CB 3.26Å; T68-D100 PolarHBondContact OG1-OD2 3Å; T68-F101 WeakPolarHBondContact O-CD2 3.14Å; T68-F101 PolarHBondContact O-N 3.2Å; T68-N327 HydrophobicContact CG2-CB 4.45Å; T68-V352 HydrophobicContact CG2-CG2 4.5Å
69H98.7Very high96.8Very high15 Ų1519.8 Ų19.87%0.06912%0.121CC..  trans-134.374.8172-57.9-83.5000110H67 F72 S79 D100 F101 D326 N327 C328H67-H69 AromaticContact CD2-CD2 3.99Å; H67-H69 AromaticContact CD2-NE2 3.34Å; H67-H69 PolarHBondContact CD2-NE2 3.35Å; H67-H69 VanDerWaalsContact CD2-NE2 3.34Å; H67-H69 AromaticContact NE2-CE1 3.85Å; H67-H69 AromaticContact NE2-NE2 3.1Å; H67-H69 PolarHBondContact NE2-NE2 2.98Å; H69-F72 HydrophobicContact CB-CB 3.81Å; H69-F72 HydrophobicContact CB-CD1 4.01Å; H69-F72 HydrophobicContact CB-CG 4.21Å; H69-S79 WeakPolarHBondContact O-CB 3.35Å; H69-S79 PolarHBondContact O-OG 3.45Å; H69-S79 VanDerWaalsContact O-OG 3.06Å; H69-D100 WeakPolarHBondContact CA-OD2 3.46Å; H69-D100 PolarHBondContact N-OD2 3.46Å; H69-F101 AromaticContact CE1-CD2 3.6Å; H69-F101 AromaticContact CE1-CG 3.84Å; H69-D326 IonicContact CD2-OD1 2.88Å; H69-D326 PolarHBondContact CD2-OD1 3.48Å; H69-D326 IonicContact NE2-OD1 3.83Å; H69-D326 PolarHBondContact NE2-OD1 3.33Å; H69-N327 CarbonylContact C-O 3.5Å; H69-N327 WeakPolarHBondContact CA-O 3.46Å; H69-N327 PolarHBondContact N-O 3.26Å; H69-C328 HydrophobicContact CB-CB 3.88Å
70M98.4Very high96.8Very high0 Ų022.8 Ų22.80%014%0.136CC..THydrogen-bonded Turntrans-76.5132179.6-55.7-53.2-177.900110.8T68 F72 D81 F83 I98 D100 V352T68-M70 HydrophobicContact CG2-CE 3.82Å; M70-F72 PolarHBondContact O-N 2.95Å; M70-D81 CarbonylContact C-O 3.5Å; M70-D81 WeakPolarHBondContact CA-O 3.41Å; M70-D81 HydrophobicContact SD-CB 4.24Å; M70-F83 HydrophobicContact CB-CD1 3.79Å; M70-F83 HydrophobicContact CB-CD2 4Å; M70-F83 HydrophobicContact CB-CE1 3.79Å; M70-F83 HydrophobicContact CB-CE2 4Å; M70-F83 HydrophobicContact CB-CG 3.89Å; M70-F83 HydrophobicContact CB-CZ 3.89Å; M70-F83 HydrophobicContact CG-CD1 4.02Å; M70-F83 HydrophobicContact CG-CE1 4.08Å; M70-I98 HydrophobicContact CE-CD1 3.9Å; M70-I98 HydrophobicContact CG-CD1 3.96Å; M70-D100 WeakPolarHBondContact CG-OD2 3.47Å; M70-D100 PolarHBondContact N-OD2 2.95Å; M70-V352 HydrophobicContact CE-CB 4.47Å; M70-V352 HydrophobicContact CE-CG2 4.06Å
71E96.8Very high96.8Very high37 Ų3722.7 Ų22.717%0.17314%0.136CC..THydrogen-bonded Turntrans54.621.1178.2-155.3169.9179.800113.6P73 R78 D81 D82 K124E71-P73 WeakPolarHBondContact O-CD 3.4Å; E71-R78 HydrophobicContact CG-CG 4.31Å; E71-R78 VanDerWaalsContact O-CG 3.22Å; E71-R78 WeakPolarHBondContact O-CG 3.41Å; E71-R78 PolarHBondContact O-NH1 3.3Å; E71-D81 PolarHBondContact N-O 2.85Å; E71-D82 HydrophobicContact CB-CB 4.06Å; E71-D82 HydrophobicContact CG-CB 4.15Å; E71-K124 IonicContact OE1-NZ 2.78Å; E71-K124 PolarHBondContact OE1-NZ 3.01Å; E71-K124 VanDerWaalsContact OE1-NZ 3.13Å; E71-K124 IonicContact OE2-NZ 3.54Å; E71-K124 PolarHBondContact OE2-NZ 3.35Å
72F97.3Very high96.7Very high9 Ų924.4 Ų24.44%0.03915%0.145CC..  trans-70.3122-170.6176.8-138.3000112.4H69 M70 F74 R78 S79 I103 W117H69-F72 HydrophobicContact CB-CB 3.81Å; H69-F72 HydrophobicContact CB-CD1 4.01Å; H69-F72 HydrophobicContact CB-CG 4.21Å; M70-F72 PolarHBondContact O-N 2.95Å; F72-F74 HydrophobicContact CD1-CB 3.63Å; F72-F74 HydrophobicContact CD1-CG 4.08Å; F72-F74 HydrophobicContact CE1-CB 3.45Å; F72-F74 VanDerWaalsContact CE1-CB 3.45Å; F72-F74 HydrophobicContact CE1-CD1 4.24Å; F72-F74 AromaticContact CE1-CD2 3.61Å; F72-F74 HydrophobicContact CE1-CD2 3.61Å; F72-F74 HydrophobicContact CE1-CE2 4.43Å; F72-F74 AromaticContact CE1-CG 3.51Å; F72-F74 HydrophobicContact CE1-CG 3.51Å; F72-F74 HydrophobicContact CG-CB 4.3Å; F72-F74 HydrophobicContact CZ-CB 3.97Å; F72-F74 AromaticContact CZ-CD2 3.83Å; F72-F74 HydrophobicContact CZ-CD2 3.83Å; F72-F74 HydrophobicContact CZ-CG 4.11Å; F72-F74 PolarHBondContact O-N 2.83Å; F72-R78 WeakPolarHBondContact O-CA 3.49Å; F72-S79 PolarHBondContact O-N 3.37Å; F72-I103 HydrophobicContact CE1-CD1 4Å; F72-I103 HydrophobicContact CE2-CB 3.88Å; F72-I103 HydrophobicContact CE2-CD1 3.88Å; F72-I103 HydrophobicContact CE2-CG1 4.28Å; F72-I103 HydrophobicContact CE2-CG2 4.37Å; F72-I103 HydrophobicContact CZ-CB 4.22Å; F72-I103 HydrophobicContact CZ-CD1 3.58Å; F72-I103 HydrophobicContact CZ-CG1 4.41Å; F72-I103 HydrophobicContact CZ-CG2 4.32Å; F72-W117 AromaticContact CD2-CZ2 3.86Å; F72-W117 HydrophobicContact CD2-CZ2 3.86Å; F72-W117 HydrophobicContact CE2-CZ2 4.23Å
73P96.1Very high96.7Very high50 Ų5024.3 Ų24.333%0.32514%0.144SC..EExtended strand (participates in β ladder)trans-72.1113.9171.8-9.624000110.8E71 S77 W120E71-P73 WeakPolarHBondContact O-CD 3.4Å; P73-S77 CarbonylContact C-O 3.2Å; P73-S77 WeakPolarHBondContact CA-O 3.13Å; P73-W120 HydrophobicContact CG-CH2 3.93Å; P73-W120 HydrophobicContact CG-CZ3 4.46Å
74F93.6Very high96.7Very high14 Ų1427.1 Ų27.16%0.06116%0.157CC..EExtended strand (participates in β ladder)trans-152.7140.8-173.5-172.5-124000112.6F72 G76 S77 Y164 Y168 F330 N347F72-F74 HydrophobicContact CD1-CB 3.63Å; F72-F74 HydrophobicContact CD1-CG 4.08Å; F72-F74 HydrophobicContact CE1-CB 3.45Å; F72-F74 VanDerWaalsContact CE1-CB 3.45Å; F72-F74 HydrophobicContact CE1-CD1 4.24Å; F72-F74 AromaticContact CE1-CD2 3.61Å; F72-F74 HydrophobicContact CE1-CD2 3.61Å; F72-F74 HydrophobicContact CE1-CE2 4.43Å; F72-F74 AromaticContact CE1-CG 3.51Å; F72-F74 HydrophobicContact CE1-CG 3.51Å; F72-F74 HydrophobicContact CG-CB 4.3Å; F72-F74 HydrophobicContact CZ-CB 3.97Å; F72-F74 AromaticContact CZ-CD2 3.83Å; F72-F74 HydrophobicContact CZ-CD2 3.83Å; F72-F74 HydrophobicContact CZ-CG 4.11Å; F72-F74 PolarHBondContact O-N 2.83Å; F74-G76 PolarHBondContact O-N 3.34Å; F74-G76 VanDerWaalsContact O-N 3.16Å; F74-S77 PolarHBondContact N-O 2.86Å; F74-S77 CarbonylContact O-C 3.53Å; F74-S77 PolarHBondContact O-N 3.38Å; F74-Y164 AromaticContact CZ-CE1 3.9Å; F74-Y164 HydrophobicContact CZ-CE1 3.9Å; F74-Y168 HydrophobicContact CD2-CE2 4.3Å; F74-Y168 AromaticContact CE2-CE2 3.9Å; F74-Y168 HydrophobicContact CE2-CE2 3.9Å; F74-F330 HydrophobicContact CB-CZ 4.29Å; F74-F330 HydrophobicContact CD1-CZ 4.24Å; F74-N347 HydrophobicContact CE1-CB 4.02Å
75M88.5Confident96.7Very high59 Ų5929.7 Ų29.729%0.29117%0.169SC..THydrogen-bonded Turntrans47.642.7178.4-64.7-176.269.600114.2S77 T343 I345 P346 N347M75-S77 VanDerWaalsContact C-N 3.26Å; M75-S77 PolarHBondContact O-N 3.41Å; M75-T343 WeakPolarHBondContact CE-O 3.45Å; M75-I345 VanDerWaalsContact CE-O 3.31Å; M75-I345 WeakPolarHBondContact CE-O 3.32Å; M75-P346 HydrophobicContact CB-CB 4.43Å; M75-N347 HydrophobicContact SD-CB 4.3Å; M75-N347 PolarHBondContact SD-ND2 3.05Å
76G86.3Confident96.7Very high86 Ų8629.7 Ų29.789%0.88717%0.169SC*.THydrogen-bonded Turntrans769.2178.500000114.8F74F74-G76 PolarHBondContact O-N 3.34Å; F74-G76 VanDerWaalsContact O-N 3.16Å
77S93.7Very high96.7Very high31 Ų3129.7 Ų29.722%0.21717%0.169CC..EExtended strand (participates in β ladder)trans-134.8-166175.1-154.20000111.1P73 F74 M75 Q334P73-S77 CarbonylContact C-O 3.2Å; P73-S77 WeakPolarHBondContact CA-O 3.13Å; F74-S77 PolarHBondContact N-O 2.86Å; F74-S77 CarbonylContact O-C 3.53Å; F74-S77 PolarHBondContact O-N 3.38Å; M75-S77 VanDerWaalsContact C-N 3.26Å; M75-S77 PolarHBondContact O-N 3.41Å; S77-Q334 PolarHBondContact OG-NE2 2.77Å
78R97Very high96.7Very high99 Ų9931.7 Ų31.737%0.37418%0.178SC..EExtended strand (participates in β ladder)trans-139.3138.6176.9-172.7-179.8-76.1-94.99.7110.2E71 F72 I80 Q334E71-R78 HydrophobicContact CG-CG 4.31Å; E71-R78 VanDerWaalsContact O-CG 3.22Å; E71-R78 WeakPolarHBondContact O-CG 3.41Å; E71-R78 PolarHBondContact O-NH1 3.3Å; F72-R78 WeakPolarHBondContact O-CA 3.49Å; R78-I80 PolarHBondContact O-N 2.88Å; R78-Q334 PolarHBondContact O-NE2 2.9Å
79S97.9Very high96.7Very high5 Ų531.7 Ų31.74%0.03518%0.178CC..  trans-53.3133.4172.7-176.90000110.4H69 F72 T329H69-S79 WeakPolarHBondContact O-CB 3.35Å; H69-S79 PolarHBondContact O-OG 3.45Å; H69-S79 VanDerWaalsContact O-OG 3.06Å; F72-S79 PolarHBondContact O-N 3.37Å; S79-T329 CarbonylContact C-O 3.48Å; S79-T329 WeakPolarHBondContact CA-O 3.47Å; S79-T329 PolarHBondContact OG-N 3.43Å; S79-T329 VanDerWaalsContact OG-N 3.13Å; S79-T329 PolarHBondContact OG-O 3.11Å
80I98.3Very high96.7Very high63 Ų6331 Ų3132%0.32317%0.174SC..SBendtrans-81.9-30.1-173.5-16569.9000112.4R78 D82 T329 A422 V423R78-I80 PolarHBondContact O-N 2.88Å; I80-D82 PolarHBondContact O-N 3.44Å; I80-T329 WeakPolarHBondContact CG2-OG1 3.16Å; I80-T329 PolarHBondContact N-O 3.13Å; I80-A422 HydrophobicContact CB-CB 4.44Å; I80-A422 HydrophobicContact CG1-CB 3.91Å; I80-A422 HydrophobicContact CG2-CB 4.07Å; I80-V423 HydrophobicContact CG2-CB 3.9Å; I80-V423 HydrophobicContact CG2-CG2 4.45Å
81D98.2Very high96.7Very high0 Ų031 Ų310%017%0.174CC..SBendtrans-72.3108.7166.4-74.1-57.3000109.1M70 E71 T329 Q421 A422M70-D81 CarbonylContact C-O 3.5Å; M70-D81 WeakPolarHBondContact CA-O 3.41Å; M70-D81 HydrophobicContact SD-CB 4.24Å; E71-D81 PolarHBondContact N-O 2.85Å; D81-T329 WeakPolarHBondContact CB-OG1 3.33Å; D81-T329 VanDerWaalsContact CG-OG1 3.3Å; D81-T329 PolarHBondContact N-OG1 2.9Å; D81-T329 WeakPolarHBondContact OD2-CB 3.19Å; D81-T329 VanDerWaalsContact OD2-CG2 3.23Å; D81-T329 WeakPolarHBondContact OD2-CG2 3.21Å; D81-T329 PolarHBondContact OD2-OG1 3.16Å; D81-Q421 WeakPolarHBondContact OD1-CA 3.31Å; D81-A422 WeakPolarHBondContact OD1-CB 3.29Å; D81-A422 PolarHBondContact OD1-N 2.85Å
82D98.5Very high96.8Very high39 Ų3929.5 Ų29.521%0.20917%0.168CC..  trans-84.4176.4169.585.6-14000111.5E71 I80 H84 Q85 G86 K124E71-D82 HydrophobicContact CB-CB 4.06Å; E71-D82 HydrophobicContact CG-CB 4.15Å; I80-D82 PolarHBondContact O-N 3.44Å; D82-H84 PolarHBondContact O-N 2.84Å; D82-H84 VanDerWaalsContact O-N 3.15Å; D82-H84 WeakPolarHBondContact OD1-CA 3.32Å; D82-H84 WeakPolarHBondContact OD1-CB 3.41Å; D82-H84 PolarHBondContact OD1-N 3.3Å; D82-Q85 PolarHBondContact O-N 2.89Å; D82-Q85 PolarHBondContact OD1-N 3.29Å; D82-G86 WeakPolarHBondContact O-CA 3.24Å; D82-G86 PolarHBondContact O-N 3.22Å; D82-K124 IonicContact OD2-NZ 3.22Å; D82-K124 PolarHBondContact OD2-NZ 3.42Å
83F98.8Very high96.9Very high0 Ų029.1 Ų29.10%017%0.167CC..Hα-helixtrans-60-26-179.6-78.8-77.9000113.7M70 T87 I98 D100 W120 A121 K124 V125M70-F83 HydrophobicContact CB-CD1 3.79Å; M70-F83 HydrophobicContact CB-CD2 4Å; M70-F83 HydrophobicContact CB-CE1 3.79Å; M70-F83 HydrophobicContact CB-CE2 4Å; M70-F83 HydrophobicContact CB-CG 3.89Å; M70-F83 HydrophobicContact CB-CZ 3.89Å; M70-F83 HydrophobicContact CG-CD1 4.02Å; M70-F83 HydrophobicContact CG-CE1 4.08Å; F83-T87 WeakPolarHBondContact O-CB 3.45Å; F83-T87 VanDerWaalsContact O-CG2 3.24Å; F83-T87 WeakPolarHBondContact O-CG2 3.41Å; F83-T87 PolarHBondContact O-N 3.49Å; F83-T87 PolarHBondContact O-OG1 3.37Å; F83-I98 HydrophobicContact CD1-CD1 4.33Å; F83-I98 HydrophobicContact CE1-CD1 4.43Å; F83-D100 HydrophobicContact CE1-CB 3.95Å; F83-D100 HydrophobicContact CZ-CB 4.16Å; F83-W120 HydrophobicContact CD2-CB 4.03Å; F83-W120 HydrophobicContact CE2-CB 4.03Å; F83-A121 HydrophobicContact CB-CB 4.46Å; F83-A121 HydrophobicContact CD1-CB 3.58Å; F83-A121 HydrophobicContact CD2-CB 3.87Å; F83-A121 HydrophobicContact CE1-CB 3.65Å; F83-A121 HydrophobicContact CE2-CB 3.94Å; F83-A121 HydrophobicContact CG-CB 3.7Å; F83-A121 HydrophobicContact CZ-CB 3.84Å; F83-K124 HydrophobicContact CB-CB 3.73Å; F83-K124 HydrophobicContact CB-CD 4.26Å; F83-V125 HydrophobicContact CB-CG1 3.98Å; F83-V125 HydrophobicContact CD1-CG1 3.78Å; F83-V125 HydrophobicContact CG-CG1 4.24Å
84H98.8Very high97Very high58 Ų5826.8 Ų26.827%0.26915%0.152SC..Hα-helixtrans-79.8-55.3178.6174.1-117.6000110.5D82 T87 K88 K124 C126D82-H84 PolarHBondContact O-N 2.84Å; D82-H84 VanDerWaalsContact O-N 3.15Å; D82-H84 WeakPolarHBondContact OD1-CA 3.32Å; D82-H84 WeakPolarHBondContact OD1-CB 3.41Å; D82-H84 PolarHBondContact OD1-N 3.3Å; H84-T87 PolarHBondContact O-OG1 2.96Å; H84-K88 WeakPolarHBondContact O-CG 3.39Å; H84-K88 PolarHBondContact O-N 3.38Å; H84-K88 VanDerWaalsContact O-N 3.11Å; H84-K124 WeakPolarHBondContact CA-O 3.23Å; H84-K124 HydrophobicContact CB-CB 4.02Å; H84-K124 HydrophobicContact CB-CG 4.46Å; H84-C126 VanDerWaalsContact CD2-SG 3.56Å
85Q98.4Very high97.2Very high57 Ų5726.1 Ų26.127%0.26615%0.149SC..Hα-helixtrans-65.9-44.4-179-166.467.136.600111.6D82 T87 K88 A89 H420 A422D82-Q85 PolarHBondContact O-N 2.89Å; D82-Q85 PolarHBondContact OD1-N 3.29Å; Q85-T87 PolarHBondContact O-N 2.88Å; Q85-K88 PolarHBondContact O-N 3.4Å; Q85-A89 WeakPolarHBondContact O-CB 3.41Å; Q85-A89 PolarHBondContact O-N 2.88Å; Q85-H420 PolarHBondContact NE2-O 3.3Å; Q85-A422 HydrophobicContact CG-CB 4Å
86G98.7Very high97.7Very high0 Ų023.4 Ų23.40%014%0.135CC..Hα-helixtrans-63.3-39.1-17900000113.3D82 A89 A90D82-G86 WeakPolarHBondContact O-CA 3.24Å; D82-G86 PolarHBondContact O-N 3.22Å; G86-A89 WeakPolarHBondContact O-CB 3.39Å; G86-A89 PolarHBondContact O-N 3.12Å; G86-A90 PolarHBondContact O-N 3.48Å
87T98.9Very high98.3Very high0 Ų019.3 Ų19.30%09%0.093CC..Hα-helixtrans-76.2-28.7175.857.30000113.1F83 H84 Q85 A90 L91 I98 V125 C126F83-T87 WeakPolarHBondContact O-CB 3.45Å; F83-T87 VanDerWaalsContact O-CG2 3.24Å; F83-T87 WeakPolarHBondContact O-CG2 3.41Å; F83-T87 PolarHBondContact O-N 3.49Å; F83-T87 PolarHBondContact O-OG1 3.37Å; H84-T87 PolarHBondContact O-OG1 2.96Å; Q85-T87 PolarHBondContact O-N 2.88Å; T87-A90 WeakPolarHBondContact O-CB 3.44Å; T87-A90 PolarHBondContact O-N 3.3Å; T87-L91 WeakPolarHBondContact O-CG 3.39Å; T87-L91 PolarHBondContact O-N 3.33Å; T87-I98 HydrophobicContact CG2-CD1 3.62Å; T87-I98 HydrophobicContact CG2-CG1 4.2Å; T87-V125 HydrophobicContact CG2-CB 4.2Å; T87-V125 HydrophobicContact CG2-CG1 4.01Å; T87-C126 WeakPolarHBondContact OG1-CB 3.28Å; T87-C126 PolarHBondContact OG1-N 3.11Å
88K98.6Very high98.6Very high44 Ų4417.8 Ų17.819%0.1918%0.083CC..Hα-helixtrans-63.6-45.1167.4-75.5-17767.5-178.60111.4H84 Q85 A90 L91 A92 C126 F453 V455H84-K88 WeakPolarHBondContact O-CG 3.39Å; H84-K88 PolarHBondContact O-N 3.38Å; H84-K88 VanDerWaalsContact O-N 3.11Å; Q85-K88 PolarHBondContact O-N 3.4Å; K88-A90 VanDerWaalsContact C-N 3.32Å; K88-A90 PolarHBondContact O-N 3.32Å; K88-L91 PolarHBondContact O-N 2.64Å; K88-A92 PolarHBondContact O-N 3.28Å; K88-C126 HydrophobicContact CG-CB 4.15Å; K88-F453 HydrophobicContact CB-CD1 4.46Å; K88-F453 HydrophobicContact CB-CE1 3.93Å; K88-F453 HydrophobicContact CB-CZ 4.19Å; K88-F453 HydrophobicContact CG-CD1 4.45Å; K88-F453 HydrophobicContact CG-CE1 4.41Å; K88-F453 VanDerWaalsContact O-CE1 3.23Å; K88-F453 WeakPolarHBondContact O-CE1 3.27Å; K88-V455 HydrophobicContact CG-CG1 4.4Å
89A98.8Very high98.7Very high0 Ų013.1 Ų13.10%07%0.065CC..Hα-helixtrans-58.3-44.6174.400000111.6Q85 G86 L91 A92 G93 V352 E353 H420 Q421Q85-A89 WeakPolarHBondContact O-CB 3.41Å; Q85-A89 PolarHBondContact O-N 2.88Å; G86-A89 WeakPolarHBondContact O-CB 3.39Å; G86-A89 PolarHBondContact O-N 3.12Å; A89-L91 PolarHBondContact O-N 2.93Å; A89-A92 PolarHBondContact O-N 3.22Å; A89-G93 PolarHBondContact O-N 3.37Å; A89-V352 HydrophobicContact CB-CG1 3.77Å; A89-E353 HydrophobicContact CB-CB 4.15Å; A89-E353 WeakPolarHBondContact O-CA 3.49Å; A89-E353 WeakPolarHBondContact O-CB 3.26Å; A89-E353 WeakPolarHBondContact O-CG 3.43Å; A89-H420 HydrophobicContact CB-CB 4.48Å; A89-H420 WeakPolarHBondContact CB-O 3.39Å; A89-Q421 HydrophobicContact CB-CG 3.64Å
90A98.9Very high98.7Very high0 Ų012.9 Ų12.90%06%0.063CC..Hα-helixtrans-54.4-49.7173.600000112G86 T87 K88 A92 G93 G94 T95 I98 V352G86-A90 PolarHBondContact O-N 3.48Å; T87-A90 WeakPolarHBondContact O-CB 3.44Å; T87-A90 PolarHBondContact O-N 3.3Å; K88-A90 VanDerWaalsContact C-N 3.32Å; K88-A90 PolarHBondContact O-N 3.32Å; A90-A92 PolarHBondContact O-N 3.4Å; A90-G93 CarbonylContact O-C 3.59Å; A90-G93 WeakPolarHBondContact O-CA 3.49Å; A90-G93 PolarHBondContact O-N 2.75Å; A90-G93 VanDerWaalsContact O-N 3.08Å; A90-G94 PolarHBondContact O-N 3.5Å; A90-T95 CarbonylContact C-O 3.52Å; A90-T95 HydrophobicContact CB-CG2 4.03Å; A90-T95 WeakPolarHBondContact O-CA 3.45Å; A90-T95 WeakPolarHBondContact O-CB 3.2Å; A90-T95 PolarHBondContact O-N 2.76Å; A90-T95 VanDerWaalsContact O-O 3.07Å; A90-I98 HydrophobicContact CB-CG2 4.2Å; A90-V352 HydrophobicContact CB-CG2 3.61Å
91L98.9Very high98.8Very high0 Ų09.9 Ų9.90%05%0.048CC..Hα-helixtrans-63.5-41.2-179.4-72.9173.4000112.8T87 K88 A89 G93 G94 T95 T96 C126 C127 T440 V447 V455T87-L91 WeakPolarHBondContact O-CG 3.39Å; T87-L91 PolarHBondContact O-N 3.33Å; K88-L91 PolarHBondContact O-N 2.64Å; A89-L91 PolarHBondContact O-N 2.93Å; L91-G93 PolarHBondContact O-N 3.41Å; L91-G94 PolarHBondContact O-N 3.05Å; L91-G94 VanDerWaalsContact O-N 3.13Å; L91-T95 WeakPolarHBondContact CA-O 3.47Å; L91-T95 PolarHBondContact N-O 2.72Å; L91-T96 HydrophobicContact CD2-CG2 4.28Å; L91-C126 HydrophobicContact CD1-CB 3.8Å; L91-C127 HydrophobicContact CD1-CB 4.16Å; L91-C127 HydrophobicContact CD2-CB 3.67Å; L91-C127 HydrophobicContact CG-CB 3.89Å; L91-T440 HydrophobicContact CB-CG2 4.48Å; L91-T440 HydrophobicContact CD2-CG2 3.76Å; L91-T440 VanDerWaalsContact O-CB 3.31Å; L91-T440 WeakPolarHBondContact O-CB 3.05Å; L91-T440 WeakPolarHBondContact O-CG2 3.42Å; L91-T440 PolarHBondContact O-OG1 2.92Å; L91-V447 HydrophobicContact CB-CG2 4.48Å; L91-V447 HydrophobicContact CD1-CB 4.14Å; L91-V447 HydrophobicContact CD1-CG2 3.85Å; L91-V447 HydrophobicContact CD2-CG2 3.65Å; L91-V447 HydrophobicContact CG-CG2 4.21Å; L91-V455 HydrophobicContact CD1-CG1 4.2Å; L91-V455 HydrophobicContact CD1-CG2 4.39Å
92A98.8Very high98.8Very high6 Ų69.9 Ų9.95%0.055%0.048CC..Hα-helixtrans-62.5-30.517400000112.2K88 A89 A90 E353 P437 Y448 F453K88-A92 PolarHBondContact O-N 3.28Å; A89-A92 PolarHBondContact O-N 3.22Å; A90-A92 PolarHBondContact O-N 3.4Å; A92-E353 HydrophobicContact CB-CG 4.48Å; A92-P437 WeakPolarHBondContact O-CG 3.23Å; A92-Y448 HydrophobicContact CB-CD2 4.14Å; A92-Y448 HydrophobicContact CB-CE1 4.4Å; A92-Y448 HydrophobicContact CB-CE2 3.85Å; A92-F453 HydrophobicContact CB-CE1 4.14Å; A92-F453 HydrophobicContact CB-CZ 3.79Å
93G98.6Very high98.8Very high1 Ų18.4 Ų8.41%0.014%0.04CC..THydrogen-bonded Turntrans-81.6-4.1174.700000115.8A89 A90 L91 E353 M356A89-G93 PolarHBondContact O-N 3.37Å; A90-G93 CarbonylContact O-C 3.59Å; A90-G93 WeakPolarHBondContact O-CA 3.49Å; A90-G93 PolarHBondContact O-N 2.75Å; A90-G93 VanDerWaalsContact O-N 3.08Å; L91-G93 PolarHBondContact O-N 3.41Å; G93-E353 WeakPolarHBondContact CA-O 3.32Å; G93-M356 VanDerWaalsContact O-CB 3.3Å; G93-M356 WeakPolarHBondContact O-CB 3.42Å; G93-M356 VanDerWaalsContact O-CG 3.27Å; G93-M356 WeakPolarHBondContact O-CG 3.39Å
94G98.8Very high98.7Very high0 Ų08.8 Ų8.80%04%0.042CC..THydrogen-bonded Turntrans80.715.4-17400000114.6G63 A90 L91 V404G63-G94 PolarHBondContact N-O 3.03Å; A90-G94 PolarHBondContact O-N 3.5Å; L91-G94 PolarHBondContact O-N 3.05Å; L91-G94 VanDerWaalsContact O-N 3.13Å; G94-V404 VanDerWaalsContact O-CG2 3.28Å; G94-V404 WeakPolarHBondContact O-CG2 3.39Å
95T98.9Very high98.5Very high0 Ų013.7 Ų13.70%07%0.066CC..EExtended strand (participates in β ladder)trans-94.7123.6169.6-66.30000109.3G63 D65 A90 L91 M97 I98 R355G63-T95 CarbonylContact O-C 3.55Å; G63-T95 WeakPolarHBondContact O-CA 3.45Å; G63-T95 WeakPolarHBondContact O-CG2 3.26Å; D65-T95 HydrophobicContact CB-CG2 3.88Å; A90-T95 CarbonylContact C-O 3.52Å; A90-T95 HydrophobicContact CB-CG2 4.03Å; A90-T95 WeakPolarHBondContact O-CA 3.45Å; A90-T95 WeakPolarHBondContact O-CB 3.2Å; A90-T95 PolarHBondContact O-N 2.76Å; A90-T95 VanDerWaalsContact O-O 3.07Å; L91-T95 WeakPolarHBondContact CA-O 3.47Å; L91-T95 PolarHBondContact N-O 2.72Å; T95-M97 VanDerWaalsContact CG2-O 3.29Å; T95-M97 WeakPolarHBondContact CG2-O 3.26Å; T95-I98 HydrophobicContact CG2-CG2 4.41Å; T95-R355 PolarHBondContact OG1-NH2 3.16Å
96T98.9Very high98.3Very high2 Ų216.7 Ų16.71%0.0128%0.078CC..EExtended strand (participates in β ladder)trans-110.7-3.5-175.856.30000113.5G62 G63 L91 C127 D128 D402 T440G62-T96 VanDerWaalsContact CA-OG1 3.3Å; G62-T96 WeakPolarHBondContact CA-OG1 3.25Å; G63-T96 PolarHBondContact O-N 3.21Å; L91-T96 HydrophobicContact CD2-CG2 4.28Å; T96-C127 WeakPolarHBondContact O-CB 3.4Å; T96-D128 PolarHBondContact O-N 3.1Å; T96-D402 HydrophobicContact CG2-CB 4.31Å; T96-T440 HydrophobicContact CG2-CG2 3.63Å
97M98.9Very high98.2Very high0 Ų019 Ų190%010%0.101CC..EExtended strand (participates in β ladder)trans-143.7140.1170.6-175.7178.9-176.700111.7G63 I64 D65 T95 I99 D128 L388 K392 I463G63-M97 PolarHBondContact O-N 3.07Å; I64-M97 WeakPolarHBondContact CA-O 3.46Å; I64-M97 HydrophobicContact CG1-CB 4.23Å; I64-M97 HydrophobicContact CG2-CB 4.34Å; I64-M97 HydrophobicContact CG2-CG 4.4Å; I64-M97 HydrophobicContact CG2-SD 4.37Å; D65-M97 PolarHBondContact N-O 3.12Å; T95-M97 VanDerWaalsContact CG2-O 3.29Å; T95-M97 WeakPolarHBondContact CG2-O 3.26Å; M97-I99 HydrophobicContact CE-CG1 4.36Å; M97-D128 WeakPolarHBondContact CA-O 3.43Å; M97-D128 WeakPolarHBondContact CG-O 3.34Å; M97-L388 HydrophobicContact CE-CD1 3.6Å; M97-L388 HydrophobicContact SD-CD1 3.66Å; M97-K392 HydrophobicContact CB-CD 4.45Å; M97-K392 HydrophobicContact CG-CD 4.45Å; M97-K392 HydrophobicContact SD-CD 3.29Å; M97-K392 WeakPolarHBondContact SD-CD 3.43Å; M97-K392 VanDerWaalsContact SD-CE 3.52Å; M97-I463 HydrophobicContact CE-CB 4.01Å; M97-I463 HydrophobicContact CE-CG1 4.25Å
98I98.9Very high98.1Very high0 Ų020.1 Ų20.10%011%0.113CC..EExtended strand (participates in β ladder)trans-115.8151.8168.666.8170.3000110.9D65 T68 M70 F83 T87 A90 T95 D128 Y129 S130 V352D65-I98 HydrophobicContact CB-CG2 4.29Å; D65-I98 CarbonylContact O-C 3.55Å; D65-I98 WeakPolarHBondContact O-CA 3.47Å; T68-I98 HydrophobicContact CG2-CB 3.99Å; T68-I98 HydrophobicContact CG2-CG2 4.08Å; M70-I98 HydrophobicContact CE-CD1 3.9Å; M70-I98 HydrophobicContact CG-CD1 3.96Å; F83-I98 HydrophobicContact CD1-CD1 4.33Å; F83-I98 HydrophobicContact CE1-CD1 4.43Å; T87-I98 HydrophobicContact CG2-CD1 3.62Å; T87-I98 HydrophobicContact CG2-CG1 4.2Å; A90-I98 HydrophobicContact CB-CG2 4.2Å; T95-I98 HydrophobicContact CG2-CG2 4.41Å; I98-D128 PolarHBondContact N-O 2.95Å; I98-Y129 CarbonylContact O-C 3.55Å; I98-Y129 WeakPolarHBondContact O-CA 3.16Å; I98-S130 PolarHBondContact O-N 3.44Å; I98-V352 HydrophobicContact CG2-CG2 4.3Å
99I98.9Very high98.1Very high0 Ų018.8 Ų18.80%011%0.109CC..EExtended strand (participates in β ladder)trans-120.9111.4166.2-41.7179.6000108.7I64 D65 T68 M97 S130 H132 F386I64-I99 HydrophobicContact CG2-CD1 4.44Å; I64-I99 HydrophobicContact CG2-CG1 4.5Å; D65-I99 PolarHBondContact O-N 3.43Å; T68-I99 PolarHBondContact N-O 3.07Å; M97-I99 HydrophobicContact CE-CG1 4.36Å; I99-S130 WeakPolarHBondContact CA-O 3.45Å; I99-H132 WeakPolarHBondContact CG2-CE1 3.47Å; I99-H132 VanDerWaalsContact CG2-NE2 3.3Å; I99-H132 WeakPolarHBondContact CG2-NE2 3.35Å; I99-F386 HydrophobicContact CD1-CB 4.17Å; I99-F386 HydrophobicContact CD1-CD2 3.65Å; I99-F386 HydrophobicContact CD1-CE2 4.25Å; I99-F386 HydrophobicContact CD1-CG 3.91Å
100D98.9Very high98.1Very high0 Ų018.8 Ų18.80%011%0.109CC..EExtended strand (participates in β ladder)trans-99.3161.1-173.7-159.5-94.2000111.4T68 H69 M70 F83 W117 S130 L131 H132T68-D100 WeakPolarHBondContact CB-OD2 3.36Å; T68-D100 WeakPolarHBondContact O-CA 3.46Å; T68-D100 WeakPolarHBondContact OG1-CA 3.36Å; T68-D100 WeakPolarHBondContact OG1-CB 3.26Å; T68-D100 PolarHBondContact OG1-OD2 3Å; H69-D100 WeakPolarHBondContact CA-OD2 3.46Å; H69-D100 PolarHBondContact N-OD2 3.46Å; M70-D100 WeakPolarHBondContact CG-OD2 3.47Å; M70-D100 PolarHBondContact N-OD2 2.95Å; F83-D100 HydrophobicContact CE1-CB 3.95Å; F83-D100 HydrophobicContact CZ-CB 4.16Å; D100-W117 PolarHBondContact OD1-NE1 2.84Å; D100-S130 PolarHBondContact N-O 3.4Å; D100-L131 HydrophobicContact CB-CD2 3.86Å; D100-L131 CarbonylContact O-C 2.99Å; D100-L131 VanDerWaalsContact O-CA 3.31Å; D100-L131 WeakPolarHBondContact O-CA 3.28Å; D100-H132 PolarHBondContact O-N 3.04Å
101F98.8Very high98.1Very high0 Ų020.5 Ų20.50%012%0.118CC..EExtended strand (participates in β ladder)trans-103.4114.4-178.3-71.3-97.6000112.2H67 T68 H69 I103 W117 H132 K159H67-F101 HydrophobicContact CB-CE2 4.29Å; H67-F101 AromaticContact CD2-CD2 3.81Å; H67-F101 AromaticContact CD2-CE2 3.17Å; H67-F101 WeakPolarHBondContact CD2-CE2 3.46Å; H67-F101 AromaticContact CD2-CZ 3.97Å; H67-F101 AromaticContact CG-CE2 3.69Å; H67-F101 AromaticContact NE2-CE2 3.5Å; H67-F101 WeakPolarHBondContact NE2-CE2 3.36Å; H67-F101 AromaticContact NE2-CZ 3.93Å; T68-F101 WeakPolarHBondContact O-CD2 3.14Å; T68-F101 PolarHBondContact O-N 3.2Å; H69-F101 AromaticContact CE1-CD2 3.6Å; H69-F101 AromaticContact CE1-CG 3.84Å; F101-I103 HydrophobicContact CB-CD1 3.92Å; F101-I103 HydrophobicContact CB-CG1 3.84Å; F101-I103 PolarHBondContact O-N 3.38Å; F101-W117 VanDerWaalsContact O-CE2 3.28Å; F101-W117 PolarHBondContact O-NE1 2.91Å; F101-H132 HydrophobicContact CD1-CB 3.53Å; F101-H132 HydrophobicContact CE1-CB 3.6Å; F101-H132 AromaticContact CE1-CD2 3.66Å; F101-H132 AromaticContact CE1-CG 3.88Å; F101-H132 AromaticContact CE2-CD2 3.57Å; F101-H132 HydrophobicContact CG-CB 4.09Å; F101-H132 HydrophobicContact CZ-CB 4.21Å; F101-H132 AromaticContact CZ-CD2 3.32Å; F101-H132 WeakPolarHBondContact CZ-CD2 3.26Å; F101-K159 HydrophobicContact CD1-CB 3.74Å; F101-K159 HydrophobicContact CD1-CD 4.43Å; F101-K159 HydrophobicContact CD1-CG 3.74Å; F101-K159 HydrophobicContact CE1-CB 3.63Å; F101-K159 HydrophobicContact CE1-CD 3.8Å; F101-K159 HydrophobicContact CE1-CG 3.59Å
102A98.8Very high98.1Very high0 Ų026.9 Ų26.90%015%0.148CC..EExtended strand (participates in β ladder)trans-76.8113.8163.900000110.1W117 H132 V133 A134A102-W117 HydrophobicContact CB-CB 4.05Å; A102-W117 HydrophobicContact CB-CD2 3.92Å; A102-W117 HydrophobicContact CB-CE3 4.28Å; A102-W117 HydrophobicContact CB-CG 3.82Å; A102-H132 PolarHBondContact N-O 2.77Å; A102-V133 HydrophobicContact CB-CG2 4.34Å; A102-V133 WeakPolarHBondContact O-CA 3.29Å; A102-A134 PolarHBondContact O-N 3.39Å
103I98.4Very high98.1Very high9 Ų927 Ų275%0.04615%0.149CC..  trans-119.1100.8-171.5-55.1178.7000110.6F72 F101 W117 A134 T136 F161 Y168F72-I103 HydrophobicContact CE1-CD1 4Å; F72-I103 HydrophobicContact CE2-CB 3.88Å; F72-I103 HydrophobicContact CE2-CD1 3.88Å; F72-I103 HydrophobicContact CE2-CG1 4.28Å; F72-I103 HydrophobicContact CE2-CG2 4.37Å; F72-I103 HydrophobicContact CZ-CB 4.22Å; F72-I103 HydrophobicContact CZ-CD1 3.58Å; F72-I103 HydrophobicContact CZ-CG1 4.41Å; F72-I103 HydrophobicContact CZ-CG2 4.32Å; F101-I103 HydrophobicContact CB-CD1 3.92Å; F101-I103 HydrophobicContact CB-CG1 3.84Å; F101-I103 PolarHBondContact O-N 3.38Å; I103-W117 HydrophobicContact CB-CH2 4.42Å; I103-W117 HydrophobicContact CB-CZ2 4.33Å; I103-W117 VanDerWaalsContact N-CZ2 3.34Å; I103-W117 VanDerWaalsContact O-CH2 3.26Å; I103-W117 WeakPolarHBondContact O-CH2 3.47Å; I103-A134 HydrophobicContact CB-CB 4.26Å; I103-A134 HydrophobicContact CG1-CB 3.96Å; I103-A134 HydrophobicContact CG2-CB 4.1Å; I103-T136 HydrophobicContact CG2-CG2 3.99Å; I103-F161 HydrophobicContact CD1-CZ 4.32Å; I103-Y168 HydrophobicContact CG2-CD1 4.48Å; I103-Y168 HydrophobicContact CG2-CE1 3.96Å; I103-Y168 HydrophobicContact CG2-CE2 4.48Å
104P97.4Very high98.1Very high7 Ų727 Ų275%0.04515%0.148CC..PPolyproline II helixtrans-69.9149.8173.828.1-32.4000111.2L110 A113 A134 T136P104-L110 HydrophobicContact CG-CD1 4.1Å; P104-L110 HydrophobicContact CG-CG 4.27Å; P104-A113 HydrophobicContact CB-CB 3.83Å; P104-A113 HydrophobicContact CG-CB 4.32Å; P104-A134 VanDerWaalsContact CD-O 3.32Å; P104-A134 WeakPolarHBondContact CD-O 3.24Å; P104-A134 WeakPolarHBondContact CG-O 3.36Å; P104-T136 WeakPolarHBondContact O-CG2 3.38Å; P104-T136 PolarHBondContact O-OG1 2.86Å
105Q94.4Very high98.1Very high162 Ų16230.4 Ų30.476%0.75717%0.165SC*.PPolyproline II helixtrans-63.3153.6162.1-65.9-1741.600110.1G107 G108Q105-G107 PolarHBondContact O-N 2.92Å; Q105-G108 PolarHBondContact O-N 2.9Å
106K94.4Very high98.1Very high119 Ų11933 Ų3352%0.51718%0.18SC..THydrogen-bonded Turntrans-55.5125.5175.5177.2158.1-171.4174.50110.7W137K106-W137 HydrophobicContact CG-CB 4.05Å
107G96.4Very high98.1Very high48 Ų4833.5 Ų33.550%0.49518%0.182SC..THydrogen-bonded Turntrans87.4-7-174.800000115.2Q105 W137Q105-G107 PolarHBondContact O-N 2.92Å; G107-W137 VanDerWaalsContact CA-CE2 3.45Å
108G97.3Very high98.1Very high25 Ų2536.1 Ų36.126%0.25819%0.192SC..SBendtrans-83.3158.817600000113.4Q105 W137Q105-G108 PolarHBondContact O-N 2.9Å; G108-W137 PolarHBondContact O-NE1 3.48Å
109S98.6Very high98.1Very high15 Ų1539.6 Ų39.611%0.10522%0.216CC..  trans-71.7134.3176.4176.90000111.8I111 E112 A113 E145S109-I111 VanDerWaalsContact C-N 3.32Å; S109-I111 PolarHBondContact OG-N 2.99Å; S109-E112 PolarHBondContact OG-N 3.35Å; S109-A113 PolarHBondContact O-N 2.89Å; S109-A113 VanDerWaalsContact O-N 3.16Å; S109-E145 WeakPolarHBondContact CA-OE2 3.39Å; S109-E145 WeakPolarHBondContact CB-OE1 3.27Å; S109-E145 PolarHBondContact OG-OE1 2.9Å; S109-E145 PolarHBondContact OG-OE2 3.3Å
110L98.8Very high98.1Very high0 Ų042.2 Ų42.20%023%0.226CC..Hα-helixtrans-69.4-33175-78.458.4000111P104 F114 V133 V135 V142 E145 M146 L149P104-L110 HydrophobicContact CG-CD1 4.1Å; P104-L110 HydrophobicContact CG-CG 4.27Å; L110-F114 WeakPolarHBondContact O-CB 3.42Å; L110-F114 PolarHBondContact O-N 3.43Å; L110-V133 HydrophobicContact CB-CG1 3.97Å; L110-V133 HydrophobicContact CD2-CG1 4.35Å; L110-V133 HydrophobicContact CG-CG1 4.07Å; L110-V135 HydrophobicContact CD2-CG2 4.18Å; L110-V142 HydrophobicContact CD1-CG1 4.25Å; L110-V142 HydrophobicContact CD1-CG2 4.03Å; L110-V142 HydrophobicContact CD2-CG1 3.9Å; L110-E145 HydrophobicContact CB-CB 4.28Å; L110-E145 WeakPolarHBondContact CB-OE2 3.36Å; L110-E145 PolarHBondContact N-OE2 3.24Å; L110-M146 HydrophobicContact CD2-CG 3.9Å; L110-L149 HydrophobicContact CB-CD1 3.76Å; L110-L149 HydrophobicContact CD2-CD1 4.44Å
111I98.8Very high98.1Very high37 Ų3742.2 Ų42.219%0.1923%0.226CC..Hα-helixtrans-69.1-46.1177.5-63.8173.5000109.9S109 A113 F114 E115 E145 I148 L149S109-I111 VanDerWaalsContact C-N 3.32Å; S109-I111 PolarHBondContact OG-N 2.99Å; I111-A113 VanDerWaalsContact C-N 3.3Å; I111-A113 PolarHBondContact O-N 2.79Å; I111-F114 WeakPolarHBondContact O-CB 3.32Å; I111-F114 PolarHBondContact O-N 3.47Å; I111-F114 VanDerWaalsContact O-N 3.15Å; I111-E115 HydrophobicContact CG2-CG 4.37Å; I111-E115 WeakPolarHBondContact O-CG 3.4Å; I111-E115 PolarHBondContact O-N 3.05Å; I111-E145 HydrophobicContact CD1-CB 4.2Å; I111-E145 HydrophobicContact CD1-CG 3.87Å; I111-E145 HydrophobicContact CG1-CB 4.11Å; I111-E145 HydrophobicContact CG1-CG 4.08Å; I111-I148 HydrophobicContact CD1-CB 4Å; I111-I148 HydrophobicContact CD1-CD1 3.93Å; I111-I148 HydrophobicContact CD1-CG2 3.71Å; I111-L149 HydrophobicContact CG1-CD2 4.38Å; I111-L149 HydrophobicContact CG1-CG 4.19Å
112E98.8Very high98.1Very high134 Ų13445 Ų4563%0.62624%0.241SC*.Hα-helixtrans-61.3-39.6177.2-67.6177.716600111.8S109 E115 T116S109-E112 PolarHBondContact OG-N 3.35Å; E112-E115 PolarHBondContact O-N 2.87Å; E112-T116 VanDerWaalsContact O-CB 3.28Å; E112-T116 WeakPolarHBondContact O-CB 3.42Å; E112-T116 PolarHBondContact O-N 3.24Å; E112-T116 PolarHBondContact O-OG1 2.74Å
113A98.7Very high98.1Very high8 Ų848.8 Ų48.87%0.06627%0.266CS..Hα-helixtrans-62.5-46172.500000111.7P104 S109 I111 E115 T116 W117P104-A113 HydrophobicContact CB-CB 3.83Å; P104-A113 HydrophobicContact CG-CB 4.32Å; S109-A113 PolarHBondContact O-N 2.89Å; S109-A113 VanDerWaalsContact O-N 3.16Å; I111-A113 VanDerWaalsContact C-N 3.3Å; I111-A113 PolarHBondContact O-N 2.79Å; A113-E115 PolarHBondContact O-N 2.72Å; A113-T116 PolarHBondContact O-N 2.76Å; A113-W117 HydrophobicContact CB-CZ3 4.29Å; A113-W117 PolarHBondContact O-N 2.96Å
114F98.9Very high98.1Very high0 Ų050.8 Ų50.80%027%0.274CS..Hα-helixtrans-56.8-49175.4172.4-90.7000112L110 I111 T116 W117 R118 L131 V133 L149 K153 V155 F462L110-F114 WeakPolarHBondContact O-CB 3.42Å; L110-F114 PolarHBondContact O-N 3.43Å; I111-F114 WeakPolarHBondContact O-CB 3.32Å; I111-F114 PolarHBondContact O-N 3.47Å; I111-F114 VanDerWaalsContact O-N 3.15Å; F114-T116 VanDerWaalsContact C-N 3.32Å; F114-T116 PolarHBondContact O-N 2.79Å; F114-W117 PolarHBondContact O-N 3.3Å; F114-R118 HydrophobicContact CD1-CG 4.08Å; F114-R118 HydrophobicContact CE1-CG 3.64Å; F114-R118 HydrophobicContact CE2-CG 4.22Å; F114-R118 HydrophobicContact CZ-CG 3.73Å; F114-R118 VanDerWaalsContact O-CG 3.31Å; F114-R118 WeakPolarHBondContact O-CG 3.25Å; F114-R118 PolarHBondContact O-N 2.93Å; F114-L131 HydrophobicContact CD2-CB 4.29Å; F114-L131 HydrophobicContact CD2-CD1 3.78Å; F114-L131 HydrophobicContact CE2-CB 4.26Å; F114-L131 HydrophobicContact CE2-CD1 3.84Å; F114-V133 HydrophobicContact CB-CG2 4.44Å; F114-V133 HydrophobicContact CD2-CG2 4.21Å; F114-L149 HydrophobicContact CB-CD2 3.67Å; F114-L149 HydrophobicContact CD1-CD2 4.24Å; F114-L149 HydrophobicContact CD2-CD2 4.08Å; F114-L149 HydrophobicContact CG-CD2 3.73Å; F114-K153 HydrophobicContact CD1-CB 4.28Å; F114-K153 HydrophobicContact CD1-CD 4.43Å; F114-K153 HydrophobicContact CD1-CG 4.34Å; F114-K153 HydrophobicContact CE1-CB 3.77Å; F114-K153 HydrophobicContact CE1-CD 3.98Å; F114-K153 HydrophobicContact CE1-CG 4.09Å; F114-K153 HydrophobicContact CE2-CB 4.32Å; F114-K153 HydrophobicContact CZ-CB 3.78Å; F114-V155 HydrophobicContact CD2-CG2 3.81Å; F114-V155 HydrophobicContact CE2-CG2 3.65Å; F114-F462 HydrophobicContact CE2-CE2 4.06Å; F114-F462 AromaticContact CE2-CZ 3.87Å; F114-F462 HydrophobicContact CE2-CZ 3.87Å; F114-F462 HydrophobicContact CZ-CE1 4.31Å; F114-F462 HydrophobicContact CZ-CE2 4.24Å; F114-F462 AromaticContact CZ-CZ 3.83Å; F114-F462 HydrophobicContact CZ-CZ 3.83Å
115E98.8Very high98.2Very high73 Ų7350.4 Ų50.434%0.34127%0.272SS..Hα-helixtrans-65.5-36.7-180-65.5-58.4160.100112.1I111 E112 A113 R118 S119 K153I111-E115 HydrophobicContact CG2-CG 4.37Å; I111-E115 WeakPolarHBondContact O-CG 3.4Å; I111-E115 PolarHBondContact O-N 3.05Å; E112-E115 PolarHBondContact O-N 2.87Å; A113-E115 PolarHBondContact O-N 2.72Å; E115-R118 PolarHBondContact O-N 3.11Å; E115-S119 WeakPolarHBondContact O-CB 3.48Å; E115-S119 PolarHBondContact O-N 3.16Å; E115-K153 VanDerWaalsContact OE1-CE 3.26Å; E115-K153 WeakPolarHBondContact OE1-CE 3.4Å; E115-K153 IonicContact OE1-NZ 2.7Å; E115-K153 PolarHBondContact OE1-NZ 2.99Å
116T98.8Very high98.4Very high53 Ų5342.8 Ų42.833%0.32524%0.236SC..Hα-helixtrans-60.1-49.1174.6-63.40000110.8E112 A113 F114 R118 S119 W120E112-T116 VanDerWaalsContact O-CB 3.28Å; E112-T116 WeakPolarHBondContact O-CB 3.42Å; E112-T116 PolarHBondContact O-N 3.24Å; E112-T116 PolarHBondContact O-OG1 2.74Å; A113-T116 PolarHBondContact O-N 2.76Å; F114-T116 VanDerWaalsContact C-N 3.32Å; F114-T116 PolarHBondContact O-N 2.79Å; T116-R118 PolarHBondContact O-N 2.9Å; T116-S119 WeakPolarHBondContact O-CB 3.37Å; T116-S119 PolarHBondContact O-N 3.4Å; T116-S119 PolarHBondContact O-OG 2.89Å; T116-W120 HydrophobicContact CG2-CD2 4.21Å; T116-W120 VanDerWaalsContact CG2-CE2 3.44Å; T116-W120 HydrophobicContact CG2-CH2 3.79Å; T116-W120 HydrophobicContact CG2-CZ2 3.22Å; T116-W120 HydrophobicContact CG2-CZ3 4.47Å; T116-W120 PolarHBondContact O-N 3.25Å; T116-W120 VanDerWaalsContact O-N 3.17Å
117W98.8Very high98.6Very high14 Ų1437.1 Ų37.15%0.05321%0.211CC..Hα-helixtrans-64.7-40.8178-94.8-113.7000112.4F72 D100 F101 A102 I103 A113 F114 S119 W120 A121 L131F72-W117 AromaticContact CD2-CZ2 3.86Å; F72-W117 HydrophobicContact CD2-CZ2 3.86Å; F72-W117 HydrophobicContact CE2-CZ2 4.23Å; D100-W117 PolarHBondContact OD1-NE1 2.84Å; F101-W117 VanDerWaalsContact O-CE2 3.28Å; F101-W117 PolarHBondContact O-NE1 2.91Å; A102-W117 HydrophobicContact CB-CB 4.05Å; A102-W117 HydrophobicContact CB-CD2 3.92Å; A102-W117 HydrophobicContact CB-CE3 4.28Å; A102-W117 HydrophobicContact CB-CG 3.82Å; I103-W117 HydrophobicContact CB-CH2 4.42Å; I103-W117 HydrophobicContact CB-CZ2 4.33Å; I103-W117 VanDerWaalsContact N-CZ2 3.34Å; I103-W117 VanDerWaalsContact O-CH2 3.26Å; I103-W117 WeakPolarHBondContact O-CH2 3.47Å; A113-W117 HydrophobicContact CB-CZ3 4.29Å; A113-W117 PolarHBondContact O-N 2.96Å; F114-W117 PolarHBondContact O-N 3.3Å; W117-S119 VanDerWaalsContact C-N 3.28Å; W117-S119 PolarHBondContact O-N 3.16Å; W117-W120 HydrophobicContact CD2-CE3 4.11Å; W117-W120 AromaticContact CD2-CZ3 3.78Å; W117-W120 HydrophobicContact CD2-CZ3 3.78Å; W117-W120 AromaticContact CE2-CZ3 3.79Å; W117-W120 HydrophobicContact CE3-CE3 4.42Å; W117-W120 HydrophobicContact CE3-CH2 4.14Å; W117-W120 AromaticContact CE3-CZ3 3.86Å; W117-W120 HydrophobicContact CE3-CZ3 3.86Å; W117-W120 HydrophobicContact CG-CE3 4.32Å; W117-W120 HydrophobicContact CG-CZ3 4.45Å; W117-W120 HydrophobicContact CH2-CH2 4.28Å; W117-W120 HydrophobicContact CH2-CZ3 4.14Å; W117-W120 HydrophobicContact CZ2-CZ3 4.01Å; W117-W120 HydrophobicContact CZ3-CH2 4.04Å; W117-W120 HydrophobicContact CZ3-CZ3 4.06Å; W117-W120 PolarHBondContact O-N 2.97Å; W117-A121 WeakPolarHBondContact O-CB 3.48Å; W117-A121 PolarHBondContact O-N 3.21Å; W117-L131 HydrophobicContact CB-CD1 3.85Å; W117-L131 HydrophobicContact CB-CD2 4.27Å
118R98.8Very high98.7Very high55 Ų5534.8 Ų34.821%0.20819%0.188CC..Hα-helixtrans-57.1-42.7172.7-72.4-66.7-55-75.3-11.8111.6F114 E115 T116 W120 A121 D122 Y129 L131F114-R118 HydrophobicContact CD1-CG 4.08Å; F114-R118 HydrophobicContact CE1-CG 3.64Å; F114-R118 HydrophobicContact CE2-CG 4.22Å; F114-R118 HydrophobicContact CZ-CG 3.73Å; F114-R118 VanDerWaalsContact O-CG 3.31Å; F114-R118 WeakPolarHBondContact O-CG 3.25Å; F114-R118 PolarHBondContact O-N 2.93Å; E115-R118 PolarHBondContact O-N 3.11Å; T116-R118 PolarHBondContact O-N 2.9Å; R118-W120 VanDerWaalsContact C-N 3.28Å; R118-W120 PolarHBondContact O-N 2.94Å; R118-A121 PolarHBondContact O-N 2.89Å; R118-D122 IonicContact CZ-OD1 2.62Å; R118-D122 IonicContact CZ-OD2 2.72Å; R118-D122 IonicContact NE-OD1 3.78Å; R118-D122 PolarHBondContact NE-OD1 2.62Å; R118-D122 IonicContact NE-OD2 3.61Å; R118-D122 PolarHBondContact NE-OD2 2.9Å; R118-D122 VanDerWaalsContact NE-OD2 3.17Å; R118-D122 IonicContact NH2-OD1 3.79Å; R118-D122 IonicContact NH2-OD2 2.84Å; R118-D122 PolarHBondContact NH2-OD2 3.15Å; R118-D122 VanDerWaalsContact O-CB 3.3Å; R118-D122 WeakPolarHBondContact O-CB 3.48Å; R118-D122 PolarHBondContact O-N 3.47Å; R118-Y129 WeakPolarHBondContact CD-OH 3.47Å; R118-Y129 PolarHBondContact NE-OH 3.18Å; R118-Y129 VanDerWaalsContact NE-OH 3.09Å; R118-L131 HydrophobicContact CG-CD1 3.94Å
119S98.8Very high98.8Very high72 Ų7233.6 Ų33.650%0.50318%0.176SC..Hα-helixtrans-64.4-30.6178.782.70000113.4E115 T116 W117 P123E115-S119 WeakPolarHBondContact O-CB 3.48Å; E115-S119 PolarHBondContact O-N 3.16Å; T116-S119 WeakPolarHBondContact O-CB 3.37Å; T116-S119 PolarHBondContact O-N 3.4Å; T116-S119 PolarHBondContact O-OG 2.89Å; W117-S119 VanDerWaalsContact C-N 3.28Å; W117-S119 PolarHBondContact O-N 3.16Å; S119-P123 WeakPolarHBondContact O-CD 3.41Å; S119-P123 WeakPolarHBondContact O-CG 3.23Å
120W98.7Very high98.8Very high55 Ų5532.9 Ų32.921%0.20817%0.171CC..Hα-helixtrans-78.2-42.7175.4-58.5-14.4000111.5P73 F83 T116 W117 R118 K124P73-W120 HydrophobicContact CG-CH2 3.93Å; P73-W120 HydrophobicContact CG-CZ3 4.46Å; F83-W120 HydrophobicContact CD2-CB 4.03Å; F83-W120 HydrophobicContact CE2-CB 4.03Å; T116-W120 HydrophobicContact CG2-CD2 4.21Å; T116-W120 VanDerWaalsContact CG2-CE2 3.44Å; T116-W120 HydrophobicContact CG2-CH2 3.79Å; T116-W120 HydrophobicContact CG2-CZ2 3.22Å; T116-W120 HydrophobicContact CG2-CZ3 4.47Å; T116-W120 PolarHBondContact O-N 3.25Å; T116-W120 VanDerWaalsContact O-N 3.17Å; W117-W120 HydrophobicContact CD2-CE3 4.11Å; W117-W120 AromaticContact CD2-CZ3 3.78Å; W117-W120 HydrophobicContact CD2-CZ3 3.78Å; W117-W120 AromaticContact CE2-CZ3 3.79Å; W117-W120 HydrophobicContact CE3-CE3 4.42Å; W117-W120 HydrophobicContact CE3-CH2 4.14Å; W117-W120 AromaticContact CE3-CZ3 3.86Å; W117-W120 HydrophobicContact CE3-CZ3 3.86Å; W117-W120 HydrophobicContact CG-CE3 4.32Å; W117-W120 HydrophobicContact CG-CZ3 4.45Å; W117-W120 HydrophobicContact CH2-CH2 4.28Å; W117-W120 HydrophobicContact CH2-CZ3 4.14Å; W117-W120 HydrophobicContact CZ2-CZ3 4.01Å; W117-W120 HydrophobicContact CZ3-CH2 4.04Å; W117-W120 HydrophobicContact CZ3-CZ3 4.06Å; W117-W120 PolarHBondContact O-N 2.97Å; R118-W120 VanDerWaalsContact C-N 3.28Å; R118-W120 PolarHBondContact O-N 2.94Å; W120-K124 WeakPolarHBondContact O-CD 3.21Å; W120-K124 WeakPolarHBondContact O-CG 3.49Å
121A98.8Very high98.8Very high0 Ų032.9 Ų32.90%017%0.171CC..Hα-helixtrans-81.5-49.4-171.100000113.9F83 W117 R118 P123 K124 V125 Y129F83-A121 HydrophobicContact CB-CB 4.46Å; F83-A121 HydrophobicContact CD1-CB 3.58Å; F83-A121 HydrophobicContact CD2-CB 3.87Å; F83-A121 HydrophobicContact CE1-CB 3.65Å; F83-A121 HydrophobicContact CE2-CB 3.94Å; F83-A121 HydrophobicContact CG-CB 3.7Å; F83-A121 HydrophobicContact CZ-CB 3.84Å; W117-A121 WeakPolarHBondContact O-CB 3.48Å; W117-A121 PolarHBondContact O-N 3.21Å; R118-A121 PolarHBondContact O-N 2.89Å; A121-P123 VanDerWaalsContact C-CD 3.43Å; A121-P123 VanDerWaalsContact C-N 3.35Å; A121-P123 VanDerWaalsContact O-N 3.16Å; A121-K124 PolarHBondContact O-N 2.84Å; A121-V125 HydrophobicContact CB-CG1 4.04Å; A121-V125 WeakPolarHBondContact O-CG1 3.49Å; A121-V125 WeakPolarHBondContact O-CG2 3.24Å; A121-V125 PolarHBondContact O-N 3Å; A121-Y129 HydrophobicContact CB-CD2 4.13Å; A121-Y129 HydrophobicContact CB-CE1 4.07Å; A121-Y129 HydrophobicContact CB-CE2 3.45Å; A121-Y129 VanDerWaalsContact CB-CE2 3.45Å; A121-Y129 VanDerWaalsContact CB-CZ 3.4Å; A121-Y129 WeakPolarHBondContact CB-OH 3.31Å
122D98.8Very high98.8Very high58 Ų5831.1 Ų31.131%0.3116%0.161SC..THydrogen-bonded Turntrans-50.6-41.4-173.5-78-14.5000114.8R118 K124 Y129R118-D122 IonicContact CZ-OD1 2.62Å; R118-D122 IonicContact CZ-OD2 2.72Å; R118-D122 IonicContact NE-OD1 3.78Å; R118-D122 PolarHBondContact NE-OD1 2.62Å; R118-D122 IonicContact NE-OD2 3.61Å; R118-D122 PolarHBondContact NE-OD2 2.9Å; R118-D122 VanDerWaalsContact NE-OD2 3.17Å; R118-D122 IonicContact NH2-OD1 3.79Å; R118-D122 IonicContact NH2-OD2 2.84Å; R118-D122 PolarHBondContact NH2-OD2 3.15Å; R118-D122 VanDerWaalsContact O-CB 3.3Å; R118-D122 WeakPolarHBondContact O-CB 3.48Å; R118-D122 PolarHBondContact O-N 3.47Å; D122-K124 VanDerWaalsContact C-N 3.34Å; D122-Y129 WeakPolarHBondContact OD1-CE1 3.35Å; D122-Y129 PolarHBondContact OD1-OH 2.92Å
123P98.7Very high98.8Very high81 Ų8124.8 Ų24.853%0.52613%0.132SC..THydrogen-bonded Turntrans-81.3-9.8177.731-34.2000114.3S119 A121 A457 G458S119-P123 WeakPolarHBondContact O-CD 3.41Å; S119-P123 WeakPolarHBondContact O-CG 3.23Å; A121-P123 VanDerWaalsContact C-CD 3.43Å; A121-P123 VanDerWaalsContact C-N 3.35Å; A121-P123 VanDerWaalsContact O-N 3.16Å; P123-A457 CarbonylContact O-C 3.57Å; P123-G458 PolarHBondContact O-N 3.06Å
124K98.8Very high98.8Very high50 Ų5024.4 Ų24.422%0.21713%0.129CC..THydrogen-bonded Turntrans-112.7-37.3-167.7-71.9-171.2-176.8-170.40114.4E71 D82 F83 H84 W120 A121 D122 C126 A457E71-K124 IonicContact OE1-NZ 2.78Å; E71-K124 PolarHBondContact OE1-NZ 3.01Å; E71-K124 VanDerWaalsContact OE1-NZ 3.13Å; E71-K124 IonicContact OE2-NZ 3.54Å; E71-K124 PolarHBondContact OE2-NZ 3.35Å; D82-K124 IonicContact OD2-NZ 3.22Å; D82-K124 PolarHBondContact OD2-NZ 3.42Å; F83-K124 HydrophobicContact CB-CB 3.73Å; F83-K124 HydrophobicContact CB-CD 4.26Å; H84-K124 WeakPolarHBondContact CA-O 3.23Å; H84-K124 HydrophobicContact CB-CB 4.02Å; H84-K124 HydrophobicContact CB-CG 4.46Å; W120-K124 WeakPolarHBondContact O-CD 3.21Å; W120-K124 WeakPolarHBondContact O-CG 3.49Å; A121-K124 PolarHBondContact O-N 2.84Å; D122-K124 VanDerWaalsContact C-N 3.34Å; K124-C126 PolarHBondContact O-N 2.98Å; K124-A457 WeakPolarHBondContact O-CA 3.28Å
125V98.8Very high98.8Very high0 Ų024.4 Ų24.40%013%0.129CC..  trans-61.1133.9-169.8-69.30000113.4F83 T87 A121 Y129 G458 D459 G460F83-V125 HydrophobicContact CB-CG1 3.98Å; F83-V125 HydrophobicContact CD1-CG1 3.78Å; F83-V125 HydrophobicContact CG-CG1 4.24Å; T87-V125 HydrophobicContact CG2-CB 4.2Å; T87-V125 HydrophobicContact CG2-CG1 4.01Å; A121-V125 HydrophobicContact CB-CG1 4.04Å; A121-V125 WeakPolarHBondContact O-CG1 3.49Å; A121-V125 WeakPolarHBondContact O-CG2 3.24Å; A121-V125 PolarHBondContact O-N 3Å; V125-Y129 HydrophobicContact CB-CD1 4.25Å; V125-Y129 HydrophobicContact CG1-CD1 3.86Å; V125-Y129 HydrophobicContact CG1-CE1 4.27Å; V125-Y129 HydrophobicContact CG1-CG 4.1Å; V125-Y129 HydrophobicContact CG2-CD1 3.76Å; V125-Y129 HydrophobicContact CG2-CE1 3.93Å; V125-G458 CarbonylContact O-C 3.46Å; V125-G458 VanDerWaalsContact O-CA 3.3Å; V125-G458 WeakPolarHBondContact O-CA 3.43Å; V125-G458 PolarHBondContact O-N 3.44Å; V125-D459 PolarHBondContact O-N 2.92Å; V125-G460 PolarHBondContact O-N 2.86Å
126C98.8Very high98.8Very high1 Ų121 Ų211%0.00711%0.113CC..SBendtrans-94.4-17.4175.5-69.20000113H84 T87 K88 L91 K124 V455H84-C126 VanDerWaalsContact CD2-SG 3.56Å; T87-C126 WeakPolarHBondContact OG1-CB 3.28Å; T87-C126 PolarHBondContact OG1-N 3.11Å; K88-C126 HydrophobicContact CG-CB 4.15Å; L91-C126 HydrophobicContact CD1-CB 3.8Å; K124-C126 PolarHBondContact O-N 2.98Å; C126-V455 HydrophobicContact CB-CB 4.45Å; C126-V455 HydrophobicContact CB-CG1 3.91Å; C126-V455 HydrophobicContact CB-CG2 3.65Å; C126-V455 WeakPolarHBondContact O-CG2 3.34Å
127C98.8Very high98.8Very high0 Ų020.3 Ų20.30%010%0.104CC..SBendtrans-128.6167.2174.770.80000110.7L91 T96 G460L91-C127 HydrophobicContact CD1-CB 4.16Å; L91-C127 HydrophobicContact CD2-CB 3.67Å; L91-C127 HydrophobicContact CG-CB 3.89Å; T96-C127 WeakPolarHBondContact O-CB 3.4Å; C127-G460 VanDerWaalsContact O-CA 3.27Å; C127-G460 WeakPolarHBondContact O-CA 3.38Å
128D98.9Very high98.8Very high0 Ų022.5 Ų22.50%011%0.113CC..EExtended strand (participates in β ladder)trans-61.2149.1179.4-80.5-9000110.5T96 M97 I98 K392 R443 K461 I463T96-D128 PolarHBondContact O-N 3.1Å; M97-D128 WeakPolarHBondContact CA-O 3.43Å; M97-D128 WeakPolarHBondContact CG-O 3.34Å; I98-D128 PolarHBondContact N-O 2.95Å; D128-K392 IonicContact OD2-NZ 2.89Å; D128-K392 PolarHBondContact OD2-NZ 3.28Å; D128-R443 VanDerWaalsContact CG-NH1 3.31Å; D128-R443 WeakPolarHBondContact OD1-CD 3.43Å; D128-R443 IonicContact OD1-CZ 2.73Å; D128-R443 IonicContact OD1-NE 2.8Å; D128-R443 IonicContact OD1-NH1 3.05Å; D128-R443 PolarHBondContact OD1-NH1 2.84Å; D128-R443 IonicContact OD2-NH1 4Å; D128-R443 PolarHBondContact OD2-NH1 3.12Å; D128-K461 WeakPolarHBondContact CA-O 3.36Å; D128-K461 PolarHBondContact OD1-N 2.86Å; D128-I463 HydrophobicContact CB-CD1 4.2Å; D128-I463 HydrophobicContact CB-CG1 3.84Å; D128-I463 WeakPolarHBondContact OD2-CD1 3.48Å
129Y98.9Very high98.8Very high0 Ų021.4 Ų21.40%011%0.113CC..EExtended strand (participates in β ladder)trans-143.2167.7178.483-72.1000111.6I98 R118 A121 D122 V125 L131 K461 F462 I463I98-Y129 CarbonylContact O-C 3.55Å; I98-Y129 WeakPolarHBondContact O-CA 3.16Å; R118-Y129 WeakPolarHBondContact CD-OH 3.47Å; R118-Y129 PolarHBondContact NE-OH 3.18Å; R118-Y129 VanDerWaalsContact NE-OH 3.09Å; A121-Y129 HydrophobicContact CB-CD2 4.13Å; A121-Y129 HydrophobicContact CB-CE1 4.07Å; A121-Y129 HydrophobicContact CB-CE2 3.45Å; A121-Y129 VanDerWaalsContact CB-CE2 3.45Å; A121-Y129 VanDerWaalsContact CB-CZ 3.4Å; A121-Y129 WeakPolarHBondContact CB-OH 3.31Å; D122-Y129 WeakPolarHBondContact OD1-CE1 3.35Å; D122-Y129 PolarHBondContact OD1-OH 2.92Å; V125-Y129 HydrophobicContact CB-CD1 4.25Å; V125-Y129 HydrophobicContact CG1-CD1 3.86Å; V125-Y129 HydrophobicContact CG1-CE1 4.27Å; V125-Y129 HydrophobicContact CG1-CG 4.1Å; V125-Y129 HydrophobicContact CG2-CD1 3.76Å; V125-Y129 HydrophobicContact CG2-CE1 3.93Å; Y129-L131 HydrophobicContact CD2-CD2 4.24Å; Y129-L131 HydrophobicContact CD2-CG 4.42Å; Y129-L131 HydrophobicContact CE2-CD1 4.4Å; Y129-L131 HydrophobicContact CE2-CD2 4.08Å; Y129-L131 HydrophobicContact CE2-CG 4.03Å; Y129-K461 PolarHBondContact N-O 3.39Å; Y129-F462 HydrophobicContact CD1-CB 4.41Å; Y129-F462 HydrophobicContact CD2-CD2 4.47Å; Y129-F462 HydrophobicContact CE1-CB 3.72Å; Y129-F462 HydrophobicContact CE1-CD2 4.45Å; Y129-F462 AromaticContact CE2-CD2 3.95Å; Y129-F462 HydrophobicContact CE2-CD2 3.95Å; Y129-F462 AromaticContact CZ-CD2 3.95Å; Y129-F462 CarbonylContact O-C 3.5Å; Y129-F462 WeakPolarHBondContact O-CA 3.45Å; Y129-I463 PolarHBondContact O-N 3.28Å
130S98.9Very high98.7Very high0 Ų024.5 Ų24.50%012%0.124CC..EExtended strand (participates in β ladder)trans-148.3178.3166.8-155.80000110.1I98 I99 D100 I463 R465I98-S130 PolarHBondContact O-N 3.44Å; I99-S130 WeakPolarHBondContact CA-O 3.45Å; D100-S130 PolarHBondContact N-O 3.4Å; S130-I463 WeakPolarHBondContact CB-O 3.37Å; S130-I463 PolarHBondContact OG-O 3.45Å; S130-R465 PolarHBondContact OG-NH1 3.45Å
131L98.9Very high98.7Very high0 Ų026.5 Ų26.50%014%0.136CC..EExtended strand (participates in β ladder)trans-125.1132.4-175.5-63.8175.5000112.9D100 F114 W117 R118 Y129 F462 R465D100-L131 HydrophobicContact CB-CD2 3.86Å; D100-L131 CarbonylContact O-C 2.99Å; D100-L131 VanDerWaalsContact O-CA 3.31Å; D100-L131 WeakPolarHBondContact O-CA 3.28Å; F114-L131 HydrophobicContact CD2-CB 4.29Å; F114-L131 HydrophobicContact CD2-CD1 3.78Å; F114-L131 HydrophobicContact CE2-CB 4.26Å; F114-L131 HydrophobicContact CE2-CD1 3.84Å; W117-L131 HydrophobicContact CB-CD1 3.85Å; W117-L131 HydrophobicContact CB-CD2 4.27Å; R118-L131 HydrophobicContact CG-CD1 3.94Å; Y129-L131 HydrophobicContact CD2-CD2 4.24Å; Y129-L131 HydrophobicContact CD2-CG 4.42Å; Y129-L131 HydrophobicContact CE2-CD1 4.4Å; Y129-L131 HydrophobicContact CE2-CD2 4.08Å; Y129-L131 HydrophobicContact CE2-CG 4.03Å; L131-F462 HydrophobicContact CB-CE2 4.36Å; L131-F462 HydrophobicContact CG-CE2 4.23Å; L131-R465 VanDerWaalsContact O-CZ 3.3Å; L131-R465 PolarHBondContact O-NH1 2.89Å; L131-R465 PolarHBondContact O-NH2 3.01Å
132H98.9Very high98.7Very high0 Ų026.5 Ų26.50%014%0.136CC..EExtended strand (participates in β ladder)trans-81.9153.5153.2-57.9-44.9000108.5T66 I99 D100 F101 A102 S157 Q190 F386T66-H132 PolarHBondContact O-NE2 2.92Å; T66-H132 VanDerWaalsContact O-NE2 3.09Å; I99-H132 WeakPolarHBondContact CG2-CE1 3.47Å; I99-H132 VanDerWaalsContact CG2-NE2 3.3Å; I99-H132 WeakPolarHBondContact CG2-NE2 3.35Å; D100-H132 PolarHBondContact O-N 3.04Å; F101-H132 HydrophobicContact CD1-CB 3.53Å; F101-H132 HydrophobicContact CE1-CB 3.6Å; F101-H132 AromaticContact CE1-CD2 3.66Å; F101-H132 AromaticContact CE1-CG 3.88Å; F101-H132 AromaticContact CE2-CD2 3.57Å; F101-H132 HydrophobicContact CG-CB 4.09Å; F101-H132 HydrophobicContact CZ-CB 4.21Å; F101-H132 AromaticContact CZ-CD2 3.32Å; F101-H132 WeakPolarHBondContact CZ-CD2 3.26Å; A102-H132 PolarHBondContact N-O 2.77Å; H132-S157 PolarHBondContact ND1-OG 3.17Å; H132-Q190 PolarHBondContact CE1-NE2 3.49Å; H132-Q190 PolarHBondContact ND1-NE2 3.09Å; H132-Q190 VanDerWaalsContact ND1-NE2 3.14Å; H132-Q190 PolarHBondContact NE2-NE2 3.46Å; H132-F386 AromaticContact CE1-CD1 3.79Å; H132-F386 AromaticContact CE1-CE1 3.41Å; H132-F386 VanDerWaalsContact CE1-CE1 3.41Å; H132-F386 WeakPolarHBondContact CE1-CE1 3.43Å; H132-F386 AromaticContact CE1-CZ 3.64Å
133V98.9Very high98.7Very high0 Ų027.6 Ų27.60%014%0.138CC..EExtended strand (participates in β ladder)trans-123.5128.2175.2-178.90000109.5A102 L110 F114 L149 V155 S157 F158 K159A102-V133 HydrophobicContact CB-CG2 4.34Å; A102-V133 WeakPolarHBondContact O-CA 3.29Å; L110-V133 HydrophobicContact CB-CG1 3.97Å; L110-V133 HydrophobicContact CD2-CG1 4.35Å; L110-V133 HydrophobicContact CG-CG1 4.07Å; F114-V133 HydrophobicContact CB-CG2 4.44Å; F114-V133 HydrophobicContact CD2-CG2 4.21Å; V133-L149 HydrophobicContact CB-CD1 4.3Å; V133-L149 HydrophobicContact CG1-CD1 3.92Å; V133-L149 HydrophobicContact CG2-CD1 4.17Å; V133-L149 HydrophobicContact CG2-CD2 4.42Å; V133-V155 HydrophobicContact CB-CG1 4.44Å; V133-V155 HydrophobicContact CG2-CG1 3.94Å; V133-V155 HydrophobicContact CG2-CG2 3.98Å; V133-S157 PolarHBondContact N-O 2.74Å; V133-F158 HydrophobicContact CB-CD1 4.08Å; V133-F158 HydrophobicContact CB-CE1 4.13Å; V133-F158 CarbonylContact O-C 3.12Å; V133-F158 VanDerWaalsContact O-CA 3.23Å; V133-F158 WeakPolarHBondContact O-CA 3.48Å; V133-K159 PolarHBondContact O-N 3.37Å
134A98.9Very high98.7Very high0 Ų027.9 Ų27.90%013%0.132CC..EExtended strand (participates in β ladder)trans-82.6140.3178.800000113.1A102 I103 P104 T136 K159 F161A102-A134 PolarHBondContact O-N 3.39Å; I103-A134 HydrophobicContact CB-CB 4.26Å; I103-A134 HydrophobicContact CG1-CB 3.96Å; I103-A134 HydrophobicContact CG2-CB 4.1Å; P104-A134 VanDerWaalsContact CD-O 3.32Å; P104-A134 WeakPolarHBondContact CD-O 3.24Å; P104-A134 WeakPolarHBondContact CG-O 3.36Å; A134-T136 HydrophobicContact CB-CG2 4.05Å; A134-K159 CarbonylContact C-O 3.6Å; A134-K159 WeakPolarHBondContact CA-O 3.36Å; A134-K159 HydrophobicContact CB-CB 4.12Å; A134-K159 HydrophobicContact CB-CG 4.38Å; A134-F161 HydrophobicContact CB-CE2 3.91Å
135V98.8Very high98.7Very high1 Ų126.3 Ų26.31%0.00613%0.125CC..  trans-103.990.6171.8178.60000106.7L110 W137 W138 V142 M146 F158 K159 M160L110-V135 HydrophobicContact CD2-CG2 4.18Å; V135-W137 VanDerWaalsContact CG1-O 3.27Å; V135-W137 WeakPolarHBondContact CG1-O 3.43Å; V135-W138 HydrophobicContact CG1-CE3 3.89Å; V135-W138 HydrophobicContact CG1-CZ3 4.23Å; V135-V142 HydrophobicContact CG1-CG1 3.91Å; V135-M146 HydrophobicContact CG2-CE 4.45Å; V135-M146 HydrophobicContact CG2-CG 4.42Å; V135-M146 HydrophobicContact CG2-SD 4.02Å; V135-F158 HydrophobicContact CG2-CB 4.03Å; V135-F158 HydrophobicContact CG2-CD1 4.1Å; V135-F158 HydrophobicContact CG2-CG 4.4Å; V135-K159 PolarHBondContact N-O 3.46Å; V135-M160 HydrophobicContact CB-CG 4.03Å; V135-M160 HydrophobicContact CB-SD 3.86Å; V135-M160 HydrophobicContact CG1-CG 4.46Å; V135-M160 HydrophobicContact CG2-SD 4.01Å
136T98.4Very high98.7Very high0 Ų026.3 Ų26.30%013%0.125CC..  trans-92-2.3-176.357.10000113.3I103 P104 A134 F161 Y168I103-T136 HydrophobicContact CG2-CG2 3.99Å; P104-T136 WeakPolarHBondContact O-CG2 3.38Å; P104-T136 PolarHBondContact O-OG1 2.86Å; A134-T136 HydrophobicContact CB-CG2 4.05Å; T136-F161 HydrophobicContact CG2-CE2 4.41Å; T136-Y168 HydrophobicContact CG2-CD1 3.45Å; T136-Y168 VanDerWaalsContact CG2-CD1 3.45Å; T136-Y168 HydrophobicContact CG2-CE1 4.11Å; T136-Y168 HydrophobicContact CG2-CG 4.03Å
137W98.4Very high98.7Very high40 Ų4029.5 Ų29.515%0.15214%0.139CC..SBendtrans-161.5169.8176.667.2-70.8000109.7K106 G107 G108 V135 S139 V142K106-W137 HydrophobicContact CG-CB 4.05Å; G107-W137 VanDerWaalsContact CA-CE2 3.45Å; G108-W137 PolarHBondContact O-NE1 3.48Å; V135-W137 VanDerWaalsContact CG1-O 3.27Å; V135-W137 WeakPolarHBondContact CG1-O 3.43Å; W137-S139 VanDerWaalsContact CH2-OG 3.23Å; W137-S139 WeakPolarHBondContact CH2-OG 3.24Å; W137-S139 VanDerWaalsContact CZ3-CB 3.43Å; W137-S139 WeakPolarHBondContact CZ3-OG 3.47Å; W137-V142 HydrophobicContact CD2-CG2 3.7Å; W137-V142 VanDerWaalsContact CE2-CG2 3.42Å; W137-V142 HydrophobicContact CE3-CG2 4.06Å; W137-V142 HydrophobicContact CG-CG2 4.3Å; W137-V142 HydrophobicContact CH2-CG2 3.97Å; W137-V142 HydrophobicContact CZ2-CG2 3.57Å; W137-V142 HydrophobicContact CZ3-CG2 4.21Å
138W98.4Very high98.7Very high60 Ų6031.8 Ų31.823%0.22715%0.151CC..  trans-132.8135.7-177.6-169.2-103.2000112.8V135 V142 K143 M146 E174 A177 A178 Q181V135-W138 HydrophobicContact CG1-CE3 3.89Å; V135-W138 HydrophobicContact CG1-CZ3 4.23Å; W138-V142 HydrophobicContact CE3-CB 4.44Å; W138-V142 HydrophobicContact CE3-CG1 3.78Å; W138-V142 HydrophobicContact CZ3-CG1 3.85Å; W138-K143 HydrophobicContact CH2-CB 4.22Å; W138-K143 HydrophobicContact CH2-CG 4.44Å; W138-K143 HydrophobicContact CZ2-CB 4.14Å; W138-K143 HydrophobicContact CZ2-CG 4.37Å; W138-M146 HydrophobicContact CH2-SD 3.92Å; W138-M146 HydrophobicContact CZ3-SD 3.53Å; W138-M146 VanDerWaalsContact CZ3-SD 3.53Å; W138-E174 HydrophobicContact CB-CB 3.93Å; W138-E174 HydrophobicContact CB-CG 3.91Å; W138-E174 HydrophobicContact CG-CB 4.42Å; W138-A177 HydrophobicContact CD2-CB 4.24Å; W138-A177 VanDerWaalsContact CE2-CB 3.46Å; W138-A177 HydrophobicContact CZ2-CB 3.72Å; W138-A177 VanDerWaalsContact NE1-CB 3.3Å; W138-A178 HydrophobicContact CE3-CB 3.87Å; W138-A178 HydrophobicContact CH2-CB 4.24Å; W138-A178 VanDerWaalsContact CZ3-CA 3.49Å; W138-A178 HydrophobicContact CZ3-CB 3.63Å; W138-Q181 HydrophobicContact CH2-CB 3.72Å; W138-Q181 HydrophobicContact CH2-CG 4.11Å; W138-Q181 HydrophobicContact CZ2-CB 4.42Å
139S98.4Very high98.7Very high32 Ų3231.8 Ų31.822%0.22415%0.151CC..SBendtrans-165.2174173.567.50000110.1W137 Q141 V142 K143W137-S139 VanDerWaalsContact CH2-OG 3.23Å; W137-S139 WeakPolarHBondContact CH2-OG 3.24Å; W137-S139 VanDerWaalsContact CZ3-CB 3.43Å; W137-S139 WeakPolarHBondContact CZ3-OG 3.47Å; S139-Q141 PolarHBondContact O-N 3.11Å; S139-Q141 PolarHBondContact OG-N 2.86Å; S139-V142 PolarHBondContact O-N 3.45Å; S139-V142 PolarHBondContact OG-N 2.77Å; S139-K143 PolarHBondContact O-N 3.21Å
140D98.4Very high98.7Very high137 Ų13732.1 Ų32.173%0.73315%0.153SC*.Hα-helixtrans-62.4-29.9172.8-68.5-28.5000112.5K143 E144D140-K143 WeakPolarHBondContact O-CB 3.38Å; D140-K143 PolarHBondContact O-N 2.81Å; D140-E144 PolarHBondContact O-N 2.75Å; D140-E144 VanDerWaalsContact O-N 3.11Å
141Q98.4Very high98.7Very high96 Ų9638 Ų3845%0.44918%0.181SC..Hα-helixtrans-62-51172.5178.1-175-5.700110.6S139 K143 E144 E145S139-Q141 PolarHBondContact O-N 3.11Å; S139-Q141 PolarHBondContact OG-N 2.86Å; Q141-K143 PolarHBondContact O-N 3.02Å; Q141-E144 PolarHBondContact O-N 2.71Å; Q141-E145 HydrophobicContact CG-CG 4.28Å; Q141-E145 PolarHBondContact NE2-OE1 2.98Å; Q141-E145 WeakPolarHBondContact O-CG 3.43Å; Q141-E145 PolarHBondContact O-N 2.79Å
142V98.8Very high98.7Very high0 Ų043.5 Ų43.50%021%0.21CC..Hα-helixtrans-57.6-42.1178.3172.50000110.5L110 V135 W137 W138 S139 E144 E145 M146L110-V142 HydrophobicContact CD1-CG1 4.25Å; L110-V142 HydrophobicContact CD1-CG2 4.03Å; L110-V142 HydrophobicContact CD2-CG1 3.9Å; V135-V142 HydrophobicContact CG1-CG1 3.91Å; W137-V142 HydrophobicContact CD2-CG2 3.7Å; W137-V142 VanDerWaalsContact CE2-CG2 3.42Å; W137-V142 HydrophobicContact CE3-CG2 4.06Å; W137-V142 HydrophobicContact CG-CG2 4.3Å; W137-V142 HydrophobicContact CH2-CG2 3.97Å; W137-V142 HydrophobicContact CZ2-CG2 3.57Å; W137-V142 HydrophobicContact CZ3-CG2 4.21Å; W138-V142 HydrophobicContact CE3-CB 4.44Å; W138-V142 HydrophobicContact CE3-CG1 3.78Å; W138-V142 HydrophobicContact CZ3-CG1 3.85Å; S139-V142 PolarHBondContact O-N 3.45Å; S139-V142 PolarHBondContact OG-N 2.77Å; V142-E144 PolarHBondContact O-N 3.36Å; V142-E145 PolarHBondContact O-N 2.96Å; V142-M146 HydrophobicContact CG1-CG 4.46Å; V142-M146 HydrophobicContact CG1-SD 4.21Å; V142-M146 VanDerWaalsContact O-CG 3.26Å; V142-M146 WeakPolarHBondContact O-CG 3.44Å; V142-M146 PolarHBondContact O-N 3.14Å
143K98.8Very high98.6Very high81 Ų8146.6 Ų46.635%0.35222%0.223SC..Hα-helixtrans-57-47.9177.2-171-174.2179.2-177.50112.1W138 S139 D140 Q141 K147 Q181W138-K143 HydrophobicContact CH2-CB 4.22Å; W138-K143 HydrophobicContact CH2-CG 4.44Å; W138-K143 HydrophobicContact CZ2-CB 4.14Å; W138-K143 HydrophobicContact CZ2-CG 4.37Å; S139-K143 PolarHBondContact O-N 3.21Å; D140-K143 WeakPolarHBondContact O-CB 3.38Å; D140-K143 PolarHBondContact O-N 2.81Å; Q141-K143 PolarHBondContact O-N 3.02Å; K143-K147 PolarHBondContact O-N 2.82Å; K143-Q181 VanDerWaalsContact CG-CD 3.43Å; K143-Q181 HydrophobicContact CG-CG 3.93Å; K143-Q181 PolarHBondContact O-NE2 3.4Å
144E98.8Very high98.6Very high88 Ų8847.1 Ų47.141%0.41123%0.229SC..Hα-helixtrans-71.7-39.5179.6-170.260.5-156.100112D140 Q141 V142 M146 K147 I148D140-E144 PolarHBondContact O-N 2.75Å; D140-E144 VanDerWaalsContact O-N 3.11Å; Q141-E144 PolarHBondContact O-N 2.71Å; V142-E144 PolarHBondContact O-N 3.36Å; E144-M146 VanDerWaalsContact C-N 3.32Å; E144-M146 PolarHBondContact O-N 3.04Å; E144-K147 WeakPolarHBondContact O-CB 3.44Å; E144-K147 PolarHBondContact O-N 2.82Å; E144-K147 IonicContact OE1-NZ 2.98Å; E144-K147 PolarHBondContact OE1-NZ 2.62Å; E144-K147 IonicContact OE2-NZ 3.59Å; E144-I148 HydrophobicContact CG-CD1 4.25Å; E144-I148 PolarHBondContact O-N 2.74Å
145E98.9Very high98.6Very high16 Ų1647.1 Ų47.18%0.07523%0.229CC..Hα-helixtrans-62.3-38.2177-72.6-176.917000112.1S109 L110 I111 Q141 V142 K147 I148 L149S109-E145 WeakPolarHBondContact CA-OE2 3.39Å; S109-E145 WeakPolarHBondContact CB-OE1 3.27Å; S109-E145 PolarHBondContact OG-OE1 2.9Å; S109-E145 PolarHBondContact OG-OE2 3.3Å; L110-E145 HydrophobicContact CB-CB 4.28Å; L110-E145 WeakPolarHBondContact CB-OE2 3.36Å; L110-E145 PolarHBondContact N-OE2 3.24Å; I111-E145 HydrophobicContact CD1-CB 4.2Å; I111-E145 HydrophobicContact CD1-CG 3.87Å; I111-E145 HydrophobicContact CG1-CB 4.11Å; I111-E145 HydrophobicContact CG1-CG 4.08Å; Q141-E145 HydrophobicContact CG-CG 4.28Å; Q141-E145 PolarHBondContact NE2-OE1 2.98Å; Q141-E145 WeakPolarHBondContact O-CG 3.43Å; Q141-E145 PolarHBondContact O-N 2.79Å; V142-E145 PolarHBondContact O-N 2.96Å; E145-K147 VanDerWaalsContact C-N 3.27Å; E145-K147 PolarHBondContact O-N 2.81Å; E145-I148 PolarHBondContact O-N 2.78Å; E145-L149 WeakPolarHBondContact O-CB 3.21Å; E145-L149 VanDerWaalsContact O-CG 3.28Å; E145-L149 WeakPolarHBondContact O-CG 3.46Å; E145-L149 PolarHBondContact O-N 2.84Å
146M98.9Very high98.6Very high0 Ų047.2 Ų47.20%023%0.229CC..Hα-helixtrans-58.1-40.6172.2-73.2172.470.300111.8L110 V135 W138 V142 E144 L149 V150 F158 Q181 C182 I185L110-M146 HydrophobicContact CD2-CG 3.9Å; V135-M146 HydrophobicContact CG2-CE 4.45Å; V135-M146 HydrophobicContact CG2-CG 4.42Å; V135-M146 HydrophobicContact CG2-SD 4.02Å; W138-M146 HydrophobicContact CH2-SD 3.92Å; W138-M146 HydrophobicContact CZ3-SD 3.53Å; W138-M146 VanDerWaalsContact CZ3-SD 3.53Å; V142-M146 HydrophobicContact CG1-CG 4.46Å; V142-M146 HydrophobicContact CG1-SD 4.21Å; V142-M146 VanDerWaalsContact O-CG 3.26Å; V142-M146 WeakPolarHBondContact O-CG 3.44Å; V142-M146 PolarHBondContact O-N 3.14Å; E144-M146 VanDerWaalsContact C-N 3.32Å; E144-M146 PolarHBondContact O-N 3.04Å; M146-L149 PolarHBondContact O-N 2.65Å; M146-V150 WeakPolarHBondContact O-CG2 3.41Å; M146-V150 PolarHBondContact O-N 2.88Å; M146-V150 VanDerWaalsContact O-N 3.12Å; M146-F158 HydrophobicContact CB-CE1 4.01Å; M146-F158 HydrophobicContact CB-CE2 4.29Å; M146-F158 HydrophobicContact CB-CZ 3.8Å; M146-F158 HydrophobicContact CE-CB 4.25Å; M146-F158 HydrophobicContact CE-CD1 4.23Å; M146-F158 HydrophobicContact CE-CD2 3.71Å; M146-F158 HydrophobicContact CE-CE2 4.1Å; M146-F158 HydrophobicContact CE-CG 3.79Å; M146-F158 HydrophobicContact CG-CD1 3.97Å; M146-F158 HydrophobicContact CG-CE1 3.69Å; M146-F158 HydrophobicContact CG-CE2 4.48Å; M146-F158 HydrophobicContact CG-CG 4.47Å; M146-F158 HydrophobicContact CG-CZ 3.97Å; M146-F158 WeakPolarHBondContact O-CZ 3.28Å; M146-Q181 HydrophobicContact CB-CG 4.35Å; M146-Q181 HydrophobicContact CE-CB 4.13Å; M146-Q181 HydrophobicContact CE-CG 3.77Å; M146-Q181 HydrophobicContact SD-CB 4.45Å; M146-Q181 HydrophobicContact SD-CG 3.87Å; M146-C182 VanDerWaalsContact CE-SG 3.58Å; M146-I185 HydrophobicContact CB-CD1 3.88Å; M146-I185 HydrophobicContact CE-CD1 4.06Å
147K98.8Very high98.6Very high68 Ų6847.2 Ų47.230%0.29623%0.229SC..Hα-helixtrans-67.2-44.5178.3177.6-176.8157.5-143.60111.3K143 E144 E145 L149 V150 Q151 I185K143-K147 PolarHBondContact O-N 2.82Å; E144-K147 WeakPolarHBondContact O-CB 3.44Å; E144-K147 PolarHBondContact O-N 2.82Å; E144-K147 IonicContact OE1-NZ 2.98Å; E144-K147 PolarHBondContact OE1-NZ 2.62Å; E144-K147 IonicContact OE2-NZ 3.59Å; E145-K147 VanDerWaalsContact C-N 3.27Å; E145-K147 PolarHBondContact O-N 2.81Å; K147-L149 PolarHBondContact O-N 3.42Å; K147-V150 PolarHBondContact O-N 3.3Å; K147-Q151 HydrophobicContact CG-CG 4.36Å; K147-Q151 WeakPolarHBondContact O-CB 3.41Å; K147-Q151 WeakPolarHBondContact O-CG 3.31Å; K147-Q151 PolarHBondContact O-N 3.41Å; K147-I185 HydrophobicContact CB-CG2 4.22Å; K147-I185 HydrophobicContact CG-CG2 4.49Å
148I98.8Very high98.6Very high48 Ų4845.3 Ų45.325%0.24622%0.222CC..Hα-helixtrans-60.5-45175.7-65.7165.6000110.7I111 E144 E145 V150 Q151 D152I111-I148 HydrophobicContact CD1-CB 4Å; I111-I148 HydrophobicContact CD1-CD1 3.93Å; I111-I148 HydrophobicContact CD1-CG2 3.71Å; E144-I148 HydrophobicContact CG-CD1 4.25Å; E144-I148 PolarHBondContact O-N 2.74Å; E145-I148 PolarHBondContact O-N 2.78Å; I148-V150 PolarHBondContact O-N 2.7Å; I148-Q151 PolarHBondContact O-N 2.85Å; I148-D152 HydrophobicContact CG2-CB 4.47Å; I148-D152 WeakPolarHBondContact O-CB 3.28Å; I148-D152 PolarHBondContact O-N 3.11Å
149L98.9Very high98.7Very high0 Ų042.6 Ų42.60%021%0.212CC..Hα-helixtrans-59-37.8177.9-76.3166.1000112.4L110 I111 F114 V133 E145 M146 K147 K153 G154 V155 F158L110-L149 HydrophobicContact CB-CD1 3.76Å; L110-L149 HydrophobicContact CD2-CD1 4.44Å; I111-L149 HydrophobicContact CG1-CD2 4.38Å; I111-L149 HydrophobicContact CG1-CG 4.19Å; F114-L149 HydrophobicContact CB-CD2 3.67Å; F114-L149 HydrophobicContact CD1-CD2 4.24Å; F114-L149 HydrophobicContact CD2-CD2 4.08Å; F114-L149 HydrophobicContact CG-CD2 3.73Å; V133-L149 HydrophobicContact CB-CD1 4.3Å; V133-L149 HydrophobicContact CG1-CD1 3.92Å; V133-L149 HydrophobicContact CG2-CD1 4.17Å; V133-L149 HydrophobicContact CG2-CD2 4.42Å; E145-L149 WeakPolarHBondContact O-CB 3.21Å; E145-L149 VanDerWaalsContact O-CG 3.28Å; E145-L149 WeakPolarHBondContact O-CG 3.46Å; E145-L149 PolarHBondContact O-N 2.84Å; M146-L149 PolarHBondContact O-N 2.65Å; K147-L149 PolarHBondContact O-N 3.42Å; L149-K153 HydrophobicContact CD2-CB 4.07Å; L149-K153 HydrophobicContact CD2-CG 4.08Å; L149-K153 CarbonylContact O-C 3.32Å; L149-K153 WeakPolarHBondContact O-CA 3.5Å; L149-K153 WeakPolarHBondContact O-CB 3.29Å; L149-K153 PolarHBondContact O-N 2.91Å; L149-G154 PolarHBondContact O-N 3.04Å; L149-G154 VanDerWaalsContact O-N 3.16Å; L149-V155 HydrophobicContact CB-CB 4.2Å; L149-V155 HydrophobicContact CB-CG2 4.4Å; L149-V155 HydrophobicContact CD2-CG2 4.32Å; L149-V155 PolarHBondContact O-N 3Å; L149-V155 VanDerWaalsContact O-N 3.11Å; L149-F158 HydrophobicContact CB-CE1 4.39Å; L149-F158 HydrophobicContact CB-CZ 4.18Å; L149-F158 HydrophobicContact CD1-CE1 3.94Å
150V98.8Very high98.7Very high7 Ų741 Ų414%0.04220%0.201CC..Hα-helixtrans-72.6-47.2176.5170.70000112.7M146 K147 I148 V155 F158 I185 A187 P467M146-V150 WeakPolarHBondContact O-CG2 3.41Å; M146-V150 PolarHBondContact O-N 2.88Å; M146-V150 VanDerWaalsContact O-N 3.12Å; K147-V150 PolarHBondContact O-N 3.3Å; I148-V150 PolarHBondContact O-N 2.7Å; V150-V155 VanDerWaalsContact CA-O 3.24Å; V150-V155 WeakPolarHBondContact CA-O 3.38Å; V150-V155 WeakPolarHBondContact CG2-O 3.33Å; V150-F158 HydrophobicContact CG2-CE2 3.69Å; V150-F158 HydrophobicContact CG2-CZ 3.91Å; V150-I185 HydrophobicContact CG1-CB 4.46Å; V150-I185 WeakPolarHBondContact CG1-O 3.42Å; V150-I185 HydrophobicContact CG2-CB 4.26Å; V150-I185 HydrophobicContact CG2-CD1 3.7Å; V150-I185 HydrophobicContact CG2-CG1 3.86Å; V150-A187 HydrophobicContact CG2-CB 4.3Å; V150-P467 HydrophobicContact CG1-CB 3.55Å; V150-P467 HydrophobicContact CG1-CG 3.64Å
151Q98Very high98.7Very high125 Ų12535.1 Ų35.158%0.58417%0.169SC*.Hα-helixtrans-73.4-41.8-173.5-70.2-179.9-23.600111.9K147 I148K147-Q151 HydrophobicContact CG-CG 4.36Å; K147-Q151 WeakPolarHBondContact O-CB 3.41Å; K147-Q151 WeakPolarHBondContact O-CG 3.31Å; K147-Q151 PolarHBondContact O-N 3.41Å; I148-Q151 PolarHBondContact O-N 2.85Å
152D98.3Very high98.7Very high115 Ų11530.6 Ų30.662%0.61515%0.148SC*.Hα-helixtrans-114.8-23.1-164.7-57.3-26.8000113.4I148I148-D152 HydrophobicContact CG2-CB 4.47Å; I148-D152 WeakPolarHBondContact O-CB 3.28Å; I148-D152 PolarHBondContact O-N 3.11Å
153K98.5Very high98.7Very high64 Ų6430.6 Ų30.628%0.27815%0.148SC..SBendtrans-111.6-3.9-172.1-52.6-63-169.1165.90114.4F114 E115 L149 F462F114-K153 HydrophobicContact CD1-CB 4.28Å; F114-K153 HydrophobicContact CD1-CD 4.43Å; F114-K153 HydrophobicContact CD1-CG 4.34Å; F114-K153 HydrophobicContact CE1-CB 3.77Å; F114-K153 HydrophobicContact CE1-CD 3.98Å; F114-K153 HydrophobicContact CE1-CG 4.09Å; F114-K153 HydrophobicContact CE2-CB 4.32Å; F114-K153 HydrophobicContact CZ-CB 3.78Å; E115-K153 VanDerWaalsContact OE1-CE 3.26Å; E115-K153 WeakPolarHBondContact OE1-CE 3.4Å; E115-K153 IonicContact OE1-NZ 2.7Å; E115-K153 PolarHBondContact OE1-NZ 2.99Å; L149-K153 HydrophobicContact CD2-CB 4.07Å; L149-K153 HydrophobicContact CD2-CG 4.08Å; L149-K153 CarbonylContact O-C 3.32Å; L149-K153 WeakPolarHBondContact O-CA 3.5Å; L149-K153 WeakPolarHBondContact O-CB 3.29Å; L149-K153 PolarHBondContact O-N 2.91Å; K153-F462 WeakPolarHBondContact O-CE1 3.3Å; K153-F462 WeakPolarHBondContact O-CZ 3.47Å
154G98.3Very high98.5Very high11 Ų1129 Ų2911%0.11314%0.14CC..  trans70.633.6175.500000113.9L149 R465L149-G154 PolarHBondContact O-N 3.04Å; L149-G154 VanDerWaalsContact O-N 3.16Å; G154-R465 CarbonylContact C-O 3.43Å; G154-R465 PolarHBondContact O-N 2.68Å
155V98.8Very high98.4Very high0 Ų028.7 Ų28.70%014%0.137CC..  trans-97.7135.7171.3177.20000108.7F114 V133 L149 V150 F158F114-V155 HydrophobicContact CD2-CG2 3.81Å; F114-V155 HydrophobicContact CE2-CG2 3.65Å; V133-V155 HydrophobicContact CB-CG1 4.44Å; V133-V155 HydrophobicContact CG2-CG1 3.94Å; V133-V155 HydrophobicContact CG2-CG2 3.98Å; L149-V155 HydrophobicContact CB-CB 4.2Å; L149-V155 HydrophobicContact CB-CG2 4.4Å; L149-V155 HydrophobicContact CD2-CG2 4.32Å; L149-V155 PolarHBondContact O-N 3Å; L149-V155 VanDerWaalsContact O-N 3.11Å; V150-V155 VanDerWaalsContact CA-O 3.24Å; V150-V155 WeakPolarHBondContact CA-O 3.38Å; V150-V155 WeakPolarHBondContact CG2-O 3.33Å; V155-F158 HydrophobicContact CG1-CE1 4.26Å; V155-F158 HydrophobicContact CG1-CZ 4.13Å
156N98.6Very high98.1Very high4 Ų434.5 Ų34.52%0.02117%0.169CC..  trans-132.524.1176.569.6-3.9000113.2A187 I188 F386 R465 K466N156-A187 CarbonylContact O-C 3.48Å; N156-A187 WeakPolarHBondContact O-CA 3.2Å; N156-A187 WeakPolarHBondContact O-CB 3.2Å; N156-I188 PolarHBondContact O-N 3.02Å; N156-F386 PolarHBondContact ND2-O 2.91Å; N156-R465 HydrophobicContact CB-CB 4.37Å; N156-R465 WeakPolarHBondContact ND2-CB 3.46Å; N156-R465 PolarHBondContact OD1-NE 3.19Å; N156-R465 PolarHBondContact OD1-NH2 3.46Å; N156-K466 PolarHBondContact ND2-O 2.89Å
157S98.9Very high97.8Very high0 Ų038.3 Ų38.30%019%0.189CC..EExtended strand (participates in β ladder)trans-156.9131-174.156.20000110.8H132 V133 I188 R465H132-S157 PolarHBondContact ND1-OG 3.17Å; V133-S157 PolarHBondContact N-O 2.74Å; S157-I188 VanDerWaalsContact CA-O 3.25Å; S157-I188 WeakPolarHBondContact CA-O 3.31Å; S157-R465 PolarHBondContact OG-NH2 3.26Å
158F98.9Very high97.7Very high0 Ų035.9 Ų35.90%018%0.178CC..EExtended strand (participates in β ladder)trans-125.4140.7-176.6-66-83.7000111.5V133 V135 M146 L149 V150 V155 M160 I185 A187 I188 Q190V133-F158 HydrophobicContact CB-CD1 4.08Å; V133-F158 HydrophobicContact CB-CE1 4.13Å; V133-F158 CarbonylContact O-C 3.12Å; V133-F158 VanDerWaalsContact O-CA 3.23Å; V133-F158 WeakPolarHBondContact O-CA 3.48Å; V135-F158 HydrophobicContact CG2-CB 4.03Å; V135-F158 HydrophobicContact CG2-CD1 4.1Å; V135-F158 HydrophobicContact CG2-CG 4.4Å; M146-F158 HydrophobicContact CB-CE1 4.01Å; M146-F158 HydrophobicContact CB-CE2 4.29Å; M146-F158 HydrophobicContact CB-CZ 3.8Å; M146-F158 HydrophobicContact CE-CB 4.25Å; M146-F158 HydrophobicContact CE-CD1 4.23Å; M146-F158 HydrophobicContact CE-CD2 3.71Å; M146-F158 HydrophobicContact CE-CE2 4.1Å; M146-F158 HydrophobicContact CE-CG 3.79Å; M146-F158 HydrophobicContact CG-CD1 3.97Å; M146-F158 HydrophobicContact CG-CE1 3.69Å; M146-F158 HydrophobicContact CG-CE2 4.48Å; M146-F158 HydrophobicContact CG-CG 4.47Å; M146-F158 HydrophobicContact CG-CZ 3.97Å; M146-F158 WeakPolarHBondContact O-CZ 3.28Å; L149-F158 HydrophobicContact CB-CE1 4.39Å; L149-F158 HydrophobicContact CB-CZ 4.18Å; L149-F158 HydrophobicContact CD1-CE1 3.94Å; V150-F158 HydrophobicContact CG2-CE2 3.69Å; V150-F158 HydrophobicContact CG2-CZ 3.91Å; V155-F158 HydrophobicContact CG1-CE1 4.26Å; V155-F158 HydrophobicContact CG1-CZ 4.13Å; F158-M160 HydrophobicContact CB-SD 4.14Å; F158-I185 HydrophobicContact CD2-CD1 4.35Å; F158-I185 HydrophobicContact CE2-CD1 3.64Å; F158-I185 HydrophobicContact CZ-CD1 4.29Å; F158-A187 HydrophobicContact CD2-CB 3.66Å; F158-A187 HydrophobicContact CE2-CB 3.65Å; F158-I188 PolarHBondContact N-O 2.89Å; F158-Q190 PolarHBondContact O-N 3.21Å
159K98.9Very high97.7Very high2 Ų234.7 Ų34.71%0.00917%0.171CC..EExtended strand (participates in β ladder)trans-109.2123.8-172.2175.262.3173179.60112.2F101 V133 A134 V135 F161 Q190 V191 H192 V247F101-K159 HydrophobicContact CD1-CB 3.74Å; F101-K159 HydrophobicContact CD1-CD 4.43Å; F101-K159 HydrophobicContact CD1-CG 3.74Å; F101-K159 HydrophobicContact CE1-CB 3.63Å; F101-K159 HydrophobicContact CE1-CD 3.8Å; F101-K159 HydrophobicContact CE1-CG 3.59Å; V133-K159 PolarHBondContact O-N 3.37Å; A134-K159 CarbonylContact C-O 3.6Å; A134-K159 WeakPolarHBondContact CA-O 3.36Å; A134-K159 HydrophobicContact CB-CB 4.12Å; A134-K159 HydrophobicContact CB-CG 4.38Å; V135-K159 PolarHBondContact N-O 3.46Å; K159-F161 HydrophobicContact CG-CE2 3.95Å; K159-F161 HydrophobicContact CG-CZ 4Å; K159-Q190 WeakPolarHBondContact CA-O 3.29Å; K159-Q190 HydrophobicContact CB-CB 4.44Å; K159-Q190 HydrophobicContact CD-CB 3.9Å; K159-V191 PolarHBondContact NZ-O 3.31Å; K159-H192 VanDerWaalsContact NZ-CA 3.31Å; K159-H192 VanDerWaalsContact NZ-CB 3.3Å; K159-V247 HydrophobicContact CD-CG1 4.46Å
160M98.9Very high97.6Very high0 Ų034.8 Ų34.80%017%0.172CC..EExtended strand (participates in β ladder)trans-115.3153.1177.5-71.667.276.400110V135 F158 V170 L175 A178 F179 A189 Q190 V191 H192V135-M160 HydrophobicContact CB-CG 4.03Å; V135-M160 HydrophobicContact CB-SD 3.86Å; V135-M160 HydrophobicContact CG1-CG 4.46Å; V135-M160 HydrophobicContact CG2-SD 4.01Å; F158-M160 HydrophobicContact CB-SD 4.14Å; M160-V170 HydrophobicContact CB-CG2 4.06Å; M160-V170 HydrophobicContact CG-CG2 4.34Å; M160-L175 HydrophobicContact CB-CD2 3.71Å; M160-L175 HydrophobicContact CG-CD2 4.11Å; M160-A178 HydrophobicContact CG-CB 4.31Å; M160-A178 HydrophobicContact SD-CB 4.46Å; M160-F179 HydrophobicContact CE-CD1 3.59Å; M160-F179 HydrophobicContact CE-CE1 3.4Å; M160-F179 VanDerWaalsContact CE-CE1 3.4Å; M160-A189 HydrophobicContact CE-CB 3.55Å; M160-Q190 PolarHBondContact N-O 3.14Å; M160-V191 HydrophobicContact CB-CG2 4.48Å; M160-V191 WeakPolarHBondContact O-CA 3.47Å; M160-H192 PolarHBondContact O-N 3Å
161F98.8Very high97.6Very high13 Ų1342.6 Ų42.66%0.05720%0.201CC..EExtended strand (participates in β ladder)trans-118.9128.6179.2-62.3-95.2000110.3I103 A134 T136 K159 Y164 Y168 M169 V170 H192I103-F161 HydrophobicContact CD1-CZ 4.32Å; A134-F161 HydrophobicContact CB-CE2 3.91Å; T136-F161 HydrophobicContact CG2-CE2 4.41Å; K159-F161 HydrophobicContact CG-CE2 3.95Å; K159-F161 HydrophobicContact CG-CZ 4Å; F161-Y164 AromaticContact CD1-CD2 3.7Å; F161-Y164 HydrophobicContact CD1-CD2 3.7Å; F161-Y164 AromaticContact CD1-CE2 3.82Å; F161-Y164 HydrophobicContact CD1-CE2 3.82Å; F161-Y164 HydrophobicContact CE1-CD2 4.29Å; F161-Y164 HydrophobicContact CE1-CE2 4.07Å; F161-Y164 HydrophobicContact CG-CD2 4.39Å; F161-Y168 HydrophobicContact CD2-CG 4.4Å; F161-M169 WeakPolarHBondContact O-CA 3.17Å; F161-V170 WeakPolarHBondContact O-CG2 3.44Å; F161-V170 PolarHBondContact O-N 2.95Å; F161-H192 HydrophobicContact CD1-CB 3.54Å; F161-H192 AromaticContact CD1-CG 3.89Å; F161-H192 HydrophobicContact CE1-CB 4.06Å; F161-H192 HydrophobicContact CG-CB 4.3Å
162M98.8Very high97.6Very high0 Ų040 Ų400%019%0.191CC..SBendtrans-93.2-9.8167.8-62.4177.172.200111.9M169 L175 V191 H192 A193 E194 G196 A229 R232 A233M162-M169 WeakPolarHBondContact O-CE 3.32Å; M162-M169 WeakPolarHBondContact O-CG 3.34Å; M162-L175 HydrophobicContact CE-CD1 4.35Å; M162-L175 HydrophobicContact CG-CD1 3.95Å; M162-L175 HydrophobicContact SD-CD1 4.3Å; M162-V191 HydrophobicContact CG-CG1 3.8Å; M162-V191 HydrophobicContact SD-CG1 3.61Å; M162-H192 WeakPolarHBondContact CB-O 3.31Å; M162-H192 PolarHBondContact N-O 3.44Å; M162-A193 HydrophobicContact SD-CB 4.47Å; M162-E194 CarbonylContact C-O 3.42Å; M162-E194 VanDerWaalsContact CB-O 3.23Å; M162-E194 WeakPolarHBondContact CB-O 3.4Å; M162-G196 WeakPolarHBondContact O-CA 3.5Å; M162-G196 PolarHBondContact O-N 3.03Å; M162-A229 HydrophobicContact CB-CB 4.48Å; M162-A229 HydrophobicContact CE-CB 3.71Å; M162-A229 WeakPolarHBondContact CE-O 3.45Å; M162-A229 HydrophobicContact SD-CB 3.95Å; M162-A229 VanDerWaalsContact SD-O 3.4Å; M162-R232 HydrophobicContact CE-CB 4.1Å; M162-R232 HydrophobicContact CE-CG 4Å; M162-A233 HydrophobicContact SD-CB 3.8Å
163A97.6Very high97.6Very high1 Ų141.5 Ų41.51%0.00820%0.198CC..SBendtrans-107.2-173.2175.600000111.8M169 H192 E194 I199A163-M169 VanDerWaalsContact O-CA 3.28Å; A163-M169 WeakPolarHBondContact O-CA 3.5Å; A163-M169 VanDerWaalsContact O-CB 3.24Å; A163-M169 WeakPolarHBondContact O-CB 3.23Å; A163-M169 PolarHBondContact O-N 3.29Å; A163-H192 WeakPolarHBondContact CB-CD2 3.46Å; A163-H192 WeakPolarHBondContact CB-NE2 3.33Å; A163-E194 HydrophobicContact CB-CB 4.11Å; A163-E194 PolarHBondContact N-O 3.12Å; A163-I199 HydrophobicContact CB-CD1 3.83Å
164Y96.1Very high97.7Very high48 Ų4840.3 Ų40.319%0.18819%0.193CC..SBendtrans5858.9-176.2-51.4-71.5000111.9F74 F161 D166 L167 Y168 M169 H192F74-Y164 AromaticContact CZ-CE1 3.9Å; F74-Y164 HydrophobicContact CZ-CE1 3.9Å; F161-Y164 AromaticContact CD1-CD2 3.7Å; F161-Y164 HydrophobicContact CD1-CD2 3.7Å; F161-Y164 AromaticContact CD1-CE2 3.82Å; F161-Y164 HydrophobicContact CD1-CE2 3.82Å; F161-Y164 HydrophobicContact CE1-CD2 4.29Å; F161-Y164 HydrophobicContact CE1-CE2 4.07Å; F161-Y164 HydrophobicContact CG-CD2 4.39Å; Y164-D166 PolarHBondContact O-N 2.89Å; Y164-L167 PolarHBondContact O-N 3.38Å; Y164-Y168 HydrophobicContact CD2-CD2 4.08Å; Y164-Y168 HydrophobicContact CG-CD2 4.2Å; Y164-Y168 PolarHBondContact O-N 3.44Å; Y164-M169 PolarHBondContact O-N 3.46Å; Y164-M169 VanDerWaalsContact O-N 3.11Å; Y164-H192 AromaticContact CE2-CE1 3.88Å
165K95.1Very high97.7Very high81 Ų8139.8 Ų39.835%0.35219%0.188SC..THydrogen-bonded Turntrans-47.8138175.9-175.4173179.1162.30110.6L167 M169 D197 A200K165-L167 PolarHBondContact O-N 2.9Å; K165-M169 HydrophobicContact CB-SD 4.1Å; K165-M169 HydrophobicContact CG-SD 4.37Å; K165-D197 WeakPolarHBondContact CD-OD1 3.27Å; K165-D197 WeakPolarHBondContact CE-OD1 3.44Å; K165-D197 IonicContact NZ-OD1 2.97Å; K165-D197 PolarHBondContact NZ-OD1 3.03Å; K165-A200 HydrophobicContact CB-CB 4.5Å; K165-A200 HydrophobicContact CD-CB 4.07Å
166D92.4Very high97.7Very high137 Ų13745.4 Ų45.473%0.73321%0.21SC*.THydrogen-bonded Turntrans65.7-10.2-177.1-52.6-41.9000116.5Y164Y164-D166 PolarHBondContact O-N 2.89Å
167L93.4Very high97.7Very high80 Ų8046.6 Ų46.642%0.41922%0.22SC..THydrogen-bonded Turntrans-104.1-65.1178.7-176.265.1000112.5Y164 K165Y164-L167 PolarHBondContact O-N 3.38Å; K165-L167 PolarHBondContact O-N 2.9Å
168Y96.4Very high97.7Very high18 Ų1846.6 Ų46.67%0.07122%0.221CC..THydrogen-bonded Turntrans-122.8-14-176.8-56.4-43.3000113.7F74 I103 T136 F161 Y164 V170F74-Y168 HydrophobicContact CD2-CE2 4.3Å; F74-Y168 AromaticContact CE2-CE2 3.9Å; F74-Y168 HydrophobicContact CE2-CE2 3.9Å; I103-Y168 HydrophobicContact CG2-CD1 4.48Å; I103-Y168 HydrophobicContact CG2-CE1 3.96Å; I103-Y168 HydrophobicContact CG2-CE2 4.48Å; T136-Y168 HydrophobicContact CG2-CD1 3.45Å; T136-Y168 VanDerWaalsContact CG2-CD1 3.45Å; T136-Y168 HydrophobicContact CG2-CE1 4.11Å; T136-Y168 HydrophobicContact CG2-CG 4.03Å; F161-Y168 HydrophobicContact CD2-CG 4.4Å; Y164-Y168 HydrophobicContact CD2-CD2 4.08Å; Y164-Y168 HydrophobicContact CG-CD2 4.2Å; Y164-Y168 PolarHBondContact O-N 3.44Å; Y168-V170 PolarHBondContact O-N 2.75Å
169M98.3Very high97.7Very high22 Ų2246.6 Ų46.611%0.10822%0.221CC..BIsolated β-bridgetrans-57.7126.7-175.9-171.4175.5176.400111.7F161 M162 A163 Y164 K165F161-M169 WeakPolarHBondContact O-CA 3.17Å; M162-M169 WeakPolarHBondContact O-CE 3.32Å; M162-M169 WeakPolarHBondContact O-CG 3.34Å; A163-M169 VanDerWaalsContact O-CA 3.28Å; A163-M169 WeakPolarHBondContact O-CA 3.5Å; A163-M169 VanDerWaalsContact O-CB 3.24Å; A163-M169 WeakPolarHBondContact O-CB 3.23Å; A163-M169 PolarHBondContact O-N 3.29Å; Y164-M169 PolarHBondContact O-N 3.46Å; Y164-M169 VanDerWaalsContact O-N 3.11Å; K165-M169 HydrophobicContact CB-SD 4.1Å; K165-M169 HydrophobicContact CG-SD 4.37Å
170V98.1Very high97.7Very high2 Ų248.3 Ų48.31%0.01223%0.233CC..  trans-105.8145.2166.8-67.90000110M160 F161 Y168 E174 L175M160-V170 HydrophobicContact CB-CG2 4.06Å; M160-V170 HydrophobicContact CG-CG2 4.34Å; F161-V170 WeakPolarHBondContact O-CG2 3.44Å; F161-V170 PolarHBondContact O-N 2.95Å; Y168-V170 PolarHBondContact O-N 2.75Å; V170-E174 WeakPolarHBondContact CA-OE2 3.3Å; V170-E174 HydrophobicContact CB-CB 4.01Å; V170-L175 HydrophobicContact CG2-CD2 3.49Å; V170-L175 VanDerWaalsContact CG2-CD2 3.49Å; V170-L175 HydrophobicContact CG2-CG 3.81Å
171R98.4Very high97.7Very high172 Ų17248.6 Ų48.665%0.64923%0.234SC*.  trans-86.6167-179-63.4175.2-65.7170.72.1111.2L173 E174 L175R171-L173 VanDerWaalsContact C-N 3.29Å; R171-L173 PolarHBondContact O-N 3.42Å; R171-L173 VanDerWaalsContact O-N 3.16Å; R171-E174 IonicContact CZ-OE1 3.95Å; R171-E174 PolarHBondContact N-OE2 3.18Å; R171-E174 IonicContact NE-OE1 3.81Å; R171-E174 PolarHBondContact NE-OE1 3.13Å; R171-E174 IonicContact NE-OE2 3.17Å; R171-E174 IonicContact NH2-OE1 3.67Å; R171-E174 PolarHBondContact NH2-OE1 2.74Å; R171-E174 CarbonylContact O-C 3.52Å; R171-E174 WeakPolarHBondContact O-CA 3.43Å; R171-E174 WeakPolarHBondContact O-CB 3.46Å; R171-E174 PolarHBondContact O-N 3.03Å; R171-L175 PolarHBondContact O-N 3.22Å
172D98.8Very high97.7Very high69 Ų6948 Ų4837%0.36923%0.231SC..Hα-helixtrans-55.9-37.8-174.9-66.6-9.3000114.4E174 L175 Y176 R232 I236D172-E174 VanDerWaalsContact C-N 3.35Å; D172-L175 PolarHBondContact O-N 3Å; D172-Y176 WeakPolarHBondContact O-CB 3.3Å; D172-Y176 PolarHBondContact O-N 2.91Å; D172-R232 IonicContact OD1-CZ 3.37Å; D172-R232 IonicContact OD1-NH1 2.98Å; D172-R232 PolarHBondContact OD1-NH1 3.24Å; D172-R232 IonicContact OD2-NH1 3.75Å; D172-I236 HydrophobicContact CB-CD1 4.02Å
173L98.4Very high97.7Very high148 Ų14850.3 Ų50.378%0.77524%0.241SC*.Hα-helixtrans-67.1-36.1175.3-69.9178.2000112.6R171 A177R171-L173 VanDerWaalsContact C-N 3.29Å; R171-L173 PolarHBondContact O-N 3.42Å; R171-L173 VanDerWaalsContact O-N 3.16Å; L173-A177 PolarHBondContact O-N 3.47Å; L173-A177 VanDerWaalsContact O-N 3.11Å
174E98.6Very high97.8Very high38 Ų3856.4 Ų56.418%0.17827%0.27CS..Hα-helixtrans-72.9-38.6177.7-63.4160.7175.300109.9W138 V170 R171 D172 A177 A178W138-E174 HydrophobicContact CB-CB 3.93Å; W138-E174 HydrophobicContact CB-CG 3.91Å; W138-E174 HydrophobicContact CG-CB 4.42Å; V170-E174 WeakPolarHBondContact CA-OE2 3.3Å; V170-E174 HydrophobicContact CB-CB 4.01Å; R171-E174 IonicContact CZ-OE1 3.95Å; R171-E174 PolarHBondContact N-OE2 3.18Å; R171-E174 IonicContact NE-OE1 3.81Å; R171-E174 PolarHBondContact NE-OE1 3.13Å; R171-E174 IonicContact NE-OE2 3.17Å; R171-E174 IonicContact NH2-OE1 3.67Å; R171-E174 PolarHBondContact NH2-OE1 2.74Å; R171-E174 CarbonylContact O-C 3.52Å; R171-E174 WeakPolarHBondContact O-CA 3.43Å; R171-E174 WeakPolarHBondContact O-CB 3.46Å; R171-E174 PolarHBondContact O-N 3.03Å; D172-E174 VanDerWaalsContact C-N 3.35Å; E174-A177 PolarHBondContact O-N 3.28Å; E174-A178 VanDerWaalsContact O-CB 3.29Å; E174-A178 WeakPolarHBondContact O-CB 3.47Å; E174-A178 PolarHBondContact O-N 3.46Å
175L98.8Very high97.9Very high0 Ų054.8 Ų54.80%026%0.264CS..Hα-helixtrans-60.8-45.9170.5-72.7171.3000111.9M160 M162 V170 R171 D172 A177 A178 F179 I236M160-L175 HydrophobicContact CB-CD2 3.71Å; M160-L175 HydrophobicContact CG-CD2 4.11Å; M162-L175 HydrophobicContact CE-CD1 4.35Å; M162-L175 HydrophobicContact CG-CD1 3.95Å; M162-L175 HydrophobicContact SD-CD1 4.3Å; V170-L175 HydrophobicContact CG2-CD2 3.49Å; V170-L175 VanDerWaalsContact CG2-CD2 3.49Å; V170-L175 HydrophobicContact CG2-CG 3.81Å; R171-L175 PolarHBondContact O-N 3.22Å; D172-L175 PolarHBondContact O-N 3Å; L175-A177 VanDerWaalsContact C-N 3.31Å; L175-A177 PolarHBondContact O-N 3Å; L175-A178 PolarHBondContact O-N 2.9Å; L175-F179 HydrophobicContact CB-CE2 4.33Å; L175-F179 HydrophobicContact CB-CZ 4.25Å; L175-F179 HydrophobicContact CD2-CE1 3.96Å; L175-F179 HydrophobicContact CD2-CZ 3.83Å; L175-F179 WeakPolarHBondContact O-CB 3.38Å; L175-F179 WeakPolarHBondContact O-CD1 3.45Å; L175-F179 WeakPolarHBondContact O-CG 3.47Å; L175-F179 PolarHBondContact O-N 2.84Å; L175-I236 HydrophobicContact CB-CD1 4.31Å; L175-I236 HydrophobicContact CB-CG2 4.43Å; L175-I236 HydrophobicContact CD1-CD1 4.15Å
176Y98.9Very high98.1Very high119 Ų11951 Ų5147%0.46725%0.249SC..Hα-helixtrans-57.3-46177-178.8-82.9000111.3D172 S180 I236 V240D172-Y176 WeakPolarHBondContact O-CB 3.3Å; D172-Y176 PolarHBondContact O-N 2.91Å; Y176-S180 WeakPolarHBondContact O-CB 3.47Å; Y176-S180 PolarHBondContact O-N 3.41Å; Y176-S180 PolarHBondContact O-OG 3.1Å; Y176-I236 HydrophobicContact CD2-CG2 4.3Å; Y176-V240 HydrophobicContact CD1-CG1 4.32Å; Y176-V240 HydrophobicContact CD2-CG1 3.53Å; Y176-V240 HydrophobicContact CE1-CG1 4.01Å; Y176-V240 HydrophobicContact CE2-CG1 3.16Å; Y176-V240 HydrophobicContact CG-CG1 4.1Å; Y176-V240 VanDerWaalsContact CZ-CG1 3.42Å
177A98.9Very high98.4Very high28 Ų2844.5 Ų44.523%0.23121%0.214CC..Hα-helixtrans-67.4-44.3178.500000112.2W138 L173 E174 L175 S180 Q181W138-A177 HydrophobicContact CD2-CB 4.24Å; W138-A177 VanDerWaalsContact CE2-CB 3.46Å; W138-A177 HydrophobicContact CZ2-CB 3.72Å; W138-A177 VanDerWaalsContact NE1-CB 3.3Å; L173-A177 PolarHBondContact O-N 3.47Å; L173-A177 VanDerWaalsContact O-N 3.11Å; E174-A177 PolarHBondContact O-N 3.28Å; L175-A177 VanDerWaalsContact C-N 3.31Å; L175-A177 PolarHBondContact O-N 3Å; A177-S180 WeakPolarHBondContact O-CB 3.44Å; A177-S180 PolarHBondContact O-N 2.98Å; A177-Q181 PolarHBondContact O-N 2.9Å
178A98.8Very high98.6Very high1 Ų140.9 Ų40.91%0.00820%0.195CC..Hα-helixtrans-63.1-43177.200000112.5W138 M160 E174 L175 Q181 C182W138-A178 HydrophobicContact CE3-CB 3.87Å; W138-A178 HydrophobicContact CH2-CB 4.24Å; W138-A178 VanDerWaalsContact CZ3-CA 3.49Å; W138-A178 HydrophobicContact CZ3-CB 3.63Å; M160-A178 HydrophobicContact CG-CB 4.31Å; M160-A178 HydrophobicContact SD-CB 4.46Å; E174-A178 VanDerWaalsContact O-CB 3.29Å; E174-A178 WeakPolarHBondContact O-CB 3.47Å; E174-A178 PolarHBondContact O-N 3.46Å; L175-A178 PolarHBondContact O-N 2.9Å; A178-Q181 PolarHBondContact O-N 2.74Å; A178-C182 WeakPolarHBondContact O-CB 3.35Å; A178-C182 PolarHBondContact O-N 3.28Å; A178-C182 PolarHBondContact O-SG 3.46Å; A178-C182 VanDerWaalsContact O-SG 3.37Å
179F98.9Very high98.7Very high0 Ų040 Ų400%019%0.191CC..Hα-helixtrans-67-39.4176.6-65.7-7.9000111.8M160 L175 Q181 C182 K183 A189 V191 I236 A237 V240 C242 L244M160-F179 HydrophobicContact CE-CD1 3.59Å; M160-F179 HydrophobicContact CE-CE1 3.4Å; M160-F179 VanDerWaalsContact CE-CE1 3.4Å; L175-F179 HydrophobicContact CB-CE2 4.33Å; L175-F179 HydrophobicContact CB-CZ 4.25Å; L175-F179 HydrophobicContact CD2-CE1 3.96Å; L175-F179 HydrophobicContact CD2-CZ 3.83Å; L175-F179 WeakPolarHBondContact O-CB 3.38Å; L175-F179 WeakPolarHBondContact O-CD1 3.45Å; L175-F179 WeakPolarHBondContact O-CG 3.47Å; L175-F179 PolarHBondContact O-N 2.84Å; F179-Q181 VanDerWaalsContact C-N 3.3Å; F179-Q181 PolarHBondContact O-N 3.06Å; F179-C182 PolarHBondContact O-N 3.01Å; F179-K183 PolarHBondContact O-N 2.88Å; F179-A189 HydrophobicContact CD1-CB 3.56Å; F179-A189 HydrophobicContact CE1-CB 3.82Å; F179-A189 HydrophobicContact CG-CB 4.4Å; F179-V191 HydrophobicContact CE1-CG2 3.8Å; F179-V191 HydrophobicContact CZ-CG2 3.61Å; F179-I236 HydrophobicContact CD2-CB 4.18Å; F179-I236 HydrophobicContact CD2-CG2 3.69Å; F179-I236 HydrophobicContact CE2-CB 4Å; F179-I236 HydrophobicContact CE2-CG2 3.9Å; F179-A237 HydrophobicContact CD2-CB 3.79Å; F179-A237 HydrophobicContact CE2-CB 3.95Å; F179-V240 HydrophobicContact CB-CG2 3.66Å; F179-C242 HydrophobicContact CB-CB 3.9Å; F179-C242 WeakPolarHBondContact O-CB 3.35Å; F179-C242 PolarHBondContact O-SG 3.21Å; F179-L244 HydrophobicContact CE1-CD1 4.3Å; F179-L244 HydrophobicContact CE2-CD1 4.46Å; F179-L244 HydrophobicContact CZ-CD1 4Å
180S98.9Very high98.8Very high38 Ų3839 Ų3927%0.26619%0.186SC..Hα-helixtrans-59.1-44.8173.5-600000110.8Y176 A177 K183 E184 V240Y176-S180 WeakPolarHBondContact O-CB 3.47Å; Y176-S180 PolarHBondContact O-N 3.41Å; Y176-S180 PolarHBondContact O-OG 3.1Å; A177-S180 WeakPolarHBondContact O-CB 3.44Å; A177-S180 PolarHBondContact O-N 2.98Å; S180-K183 WeakPolarHBondContact O-CB 3.48Å; S180-K183 PolarHBondContact O-N 3.47Å; S180-E184 PolarHBondContact O-N 2.76Å; S180-V240 WeakPolarHBondContact OG-CG1 3.2Å
181Q98.9Very high98.8Very high5 Ų538.9 Ų38.92%0.02319%0.185CC..Hα-helixtrans-65-45.3177.1-178.160.88.500112W138 K143 M146 A177 A178 F179 K183 E184 I185W138-Q181 HydrophobicContact CH2-CB 3.72Å; W138-Q181 HydrophobicContact CH2-CG 4.11Å; W138-Q181 HydrophobicContact CZ2-CB 4.42Å; K143-Q181 VanDerWaalsContact CG-CD 3.43Å; K143-Q181 HydrophobicContact CG-CG 3.93Å; K143-Q181 PolarHBondContact O-NE2 3.4Å; M146-Q181 HydrophobicContact CB-CG 4.35Å; M146-Q181 HydrophobicContact CE-CB 4.13Å; M146-Q181 HydrophobicContact CE-CG 3.77Å; M146-Q181 HydrophobicContact SD-CB 4.45Å; M146-Q181 HydrophobicContact SD-CG 3.87Å; A177-Q181 PolarHBondContact O-N 2.9Å; A178-Q181 PolarHBondContact O-N 2.74Å; F179-Q181 VanDerWaalsContact C-N 3.3Å; F179-Q181 PolarHBondContact O-N 3.06Å; Q181-K183 VanDerWaalsContact C-N 3.29Å; Q181-K183 PolarHBondContact O-N 3.33Å; Q181-E184 PolarHBondContact O-N 3.38Å; Q181-E184 VanDerWaalsContact O-N 3.12Å; Q181-E184 PolarHBondContact OE1-OE2 2.91Å; Q181-I185 HydrophobicContact CG-CD1 4.21Å; Q181-I185 VanDerWaalsContact O-CG1 3.25Å; Q181-I185 WeakPolarHBondContact O-CG1 3.37Å; Q181-I185 PolarHBondContact O-N 3.45Å
182C98.9Very high98.8Very high0 Ų030.7 Ų30.70%016%0.155CC..Hα-helixtrans-53.8-45.5173.8-78.40000111.7M146 A178 F179 G186 A187 A189 Y473M146-C182 VanDerWaalsContact CE-SG 3.58Å; A178-C182 WeakPolarHBondContact O-CB 3.35Å; A178-C182 PolarHBondContact O-N 3.28Å; A178-C182 PolarHBondContact O-SG 3.46Å; A178-C182 VanDerWaalsContact O-SG 3.37Å; F179-C182 PolarHBondContact O-N 3.01Å; C182-G186 PolarHBondContact O-N 3.49Å; C182-A187 CarbonylContact C-O 3.58Å; C182-A187 WeakPolarHBondContact CB-O 3.2Å; C182-A187 PolarHBondContact O-N 2.9Å; C182-A187 VanDerWaalsContact O-O 3.1Å; C182-A189 HydrophobicContact CB-CB 4.35Å; C182-Y473 PolarHBondContact O-OH 3.39Å
183K98.8Very high98.8Very high49 Ų4927.6 Ų27.621%0.21314%0.138CC..Hα-helixtrans-60.4-48.8174.6178.5179.3-175.6-75.10112.1F179 S180 Q181 I185 G186 V240 N241 C242 D480F179-K183 PolarHBondContact O-N 2.88Å; S180-K183 WeakPolarHBondContact O-CB 3.48Å; S180-K183 PolarHBondContact O-N 3.47Å; Q181-K183 VanDerWaalsContact C-N 3.29Å; Q181-K183 PolarHBondContact O-N 3.33Å; K183-I185 VanDerWaalsContact C-N 3.34Å; K183-I185 PolarHBondContact O-N 2.99Å; K183-G186 PolarHBondContact O-N 2.99Å; K183-V240 WeakPolarHBondContact CD-O 3.36Å; K183-N241 HydrophobicContact CD-CB 4.36Å; K183-N241 WeakPolarHBondContact CD-O 3.46Å; K183-N241 WeakPolarHBondContact CE-O 3.36Å; K183-C242 HydrophobicContact CB-CB 4.22Å; K183-D480 VanDerWaalsContact CE-OD1 3.26Å; K183-D480 WeakPolarHBondContact CE-OD1 3.5Å; K183-D480 VanDerWaalsContact CE-OD2 3.3Å; K183-D480 WeakPolarHBondContact CE-OD2 3.45Å; K183-D480 VanDerWaalsContact NZ-CG 3.28Å; K183-D480 IonicContact NZ-OD1 2.75Å; K183-D480 PolarHBondContact NZ-OD1 3.26Å; K183-D480 IonicContact NZ-OD2 2.86Å; K183-D480 PolarHBondContact NZ-OD2 3.1Å
184E98.8Very high98.8Very high129 Ų12920.5 Ų20.560%0.60310%0.101SC*.Hα-helixtrans-58.4-44.2-177.3-172.9178161.900111.9S180 Q181 G186 F468S180-E184 PolarHBondContact O-N 2.76Å; Q181-E184 PolarHBondContact O-N 3.38Å; Q181-E184 VanDerWaalsContact O-N 3.12Å; Q181-E184 PolarHBondContact OE1-OE2 2.91Å; E184-G186 VanDerWaalsContact C-N 3.35Å; E184-F468 WeakPolarHBondContact O-CZ 3.27Å
185I98.8Very high98.9Very high15 Ų1519.8 Ų19.88%0.07710%0.099CC..Hα-helixtrans-88.3-0.1-178.670.4-166.2000113.5M146 K147 V150 F158 Q181 K183 A187 P467M146-I185 HydrophobicContact CB-CD1 3.88Å; M146-I185 HydrophobicContact CE-CD1 4.06Å; K147-I185 HydrophobicContact CB-CG2 4.22Å; K147-I185 HydrophobicContact CG-CG2 4.49Å; V150-I185 HydrophobicContact CG1-CB 4.46Å; V150-I185 WeakPolarHBondContact CG1-O 3.42Å; V150-I185 HydrophobicContact CG2-CB 4.26Å; V150-I185 HydrophobicContact CG2-CD1 3.7Å; V150-I185 HydrophobicContact CG2-CG1 3.86Å; F158-I185 HydrophobicContact CD2-CD1 4.35Å; F158-I185 HydrophobicContact CE2-CD1 3.64Å; F158-I185 HydrophobicContact CZ-CD1 4.29Å; Q181-I185 HydrophobicContact CG-CD1 4.21Å; Q181-I185 VanDerWaalsContact O-CG1 3.25Å; Q181-I185 WeakPolarHBondContact O-CG1 3.37Å; Q181-I185 PolarHBondContact O-N 3.45Å; K183-I185 VanDerWaalsContact C-N 3.34Å; K183-I185 PolarHBondContact O-N 2.99Å; I185-A187 HydrophobicContact CD1-CB 4.22Å; I185-A187 HydrophobicContact CG1-CB 3.87Å; I185-P467 VanDerWaalsContact O-CB 3.26Å; I185-P467 WeakPolarHBondContact O-CB 3.34Å
186G98.8Very high98.8Very high2 Ų219.8 Ų19.82%0.02110%0.099CC..THydrogen-bonded Turntrans74.626.8178.700000114.8C182 K183 E184 P467 F468 Y473C182-G186 PolarHBondContact O-N 3.49Å; K183-G186 PolarHBondContact O-N 2.99Å; E184-G186 VanDerWaalsContact C-N 3.35Å; G186-P467 CarbonylContact O-C 3.54Å; G186-P467 WeakPolarHBondContact O-CA 3.43Å; G186-F468 VanDerWaalsContact CA-CD1 3.46Å; G186-F468 PolarHBondContact O-N 3.38Å; G186-Y473 VanDerWaalsContact C-CZ 3.43Å; G186-Y473 VanDerWaalsContact CA-CZ 3.47Å; G186-Y473 WeakPolarHBondContact CA-OH 3.49Å; G186-Y473 WeakPolarHBondContact O-CE2 3.41Å
187A98.9Very high98.8Very high0 Ų017.6 Ų17.60%010%0.095CC..PPolyproline II helixtrans-102147.9176.800000113.2V150 N156 F158 C182 I185 Y473V150-A187 HydrophobicContact CG2-CB 4.3Å; N156-A187 CarbonylContact O-C 3.48Å; N156-A187 WeakPolarHBondContact O-CA 3.2Å; N156-A187 WeakPolarHBondContact O-CB 3.2Å; F158-A187 HydrophobicContact CD2-CB 3.66Å; F158-A187 HydrophobicContact CE2-CB 3.65Å; C182-A187 CarbonylContact C-O 3.58Å; C182-A187 WeakPolarHBondContact CB-O 3.2Å; C182-A187 PolarHBondContact O-N 2.9Å; C182-A187 VanDerWaalsContact O-O 3.1Å; I185-A187 HydrophobicContact CD1-CB 4.22Å; I185-A187 HydrophobicContact CG1-CB 3.87Å; A187-Y473 VanDerWaalsContact C-OH 3.23Å; A187-Y473 PolarHBondContact N-OH 3.16Å; A187-Y473 PolarHBondContact O-OH 2.89Å
188I98.9Very high98.8Very high3 Ų320.6 Ų20.62%0.01511%0.107CC..EExtended strand (participates in β ladder)trans-80.7132.6172.7-170167.2000111.6N156 S157 F158 P243 Y245 Y269 I385 F386 I472N156-I188 PolarHBondContact O-N 3.02Å; S157-I188 VanDerWaalsContact CA-O 3.25Å; S157-I188 WeakPolarHBondContact CA-O 3.31Å; F158-I188 PolarHBondContact N-O 2.89Å; I188-P243 HydrophobicContact CG1-CB 4.22Å; I188-P243 HydrophobicContact CG1-CG 4.4Å; I188-Y245 HydrophobicContact CD1-CD2 4.17Å; I188-Y245 HydrophobicContact CD1-CG 4.42Å; I188-Y269 HydrophobicContact CD1-CD2 4Å; I188-Y269 HydrophobicContact CD1-CE2 4.36Å; I188-I385 HydrophobicContact CD1-CG2 3.86Å; I188-F386 HydrophobicContact CG2-CD1 4.24Å; I188-F386 HydrophobicContact CG2-CE1 3.87Å; I188-I472 HydrophobicContact CB-CD1 4.33Å; I188-I472 HydrophobicContact CD1-CD1 3.82Å
189A98.9Very high98.8Very high0 Ų021.3 Ų21.30%011%0.11CC..EExtended strand (participates in β ladder)trans-81.5130.6171.900000110.2M160 F179 C182 P243 L244 Y245M160-A189 HydrophobicContact CE-CB 3.55Å; F179-A189 HydrophobicContact CD1-CB 3.56Å; F179-A189 HydrophobicContact CE1-CB 3.82Å; F179-A189 HydrophobicContact CG-CB 4.4Å; C182-A189 HydrophobicContact CB-CB 4.35Å; A189-P243 PolarHBondContact N-O 2.98Å; A189-L244 HydrophobicContact CB-CD1 4.16Å; A189-L244 CarbonylContact O-C 3.34Å; A189-L244 WeakPolarHBondContact O-CA 3.36Å; A189-Y245 PolarHBondContact O-N 2.87Å
190Q98.9Very high98.8Very high0 Ų022.5 Ų22.50%012%0.12CC..EExtended strand (participates in β ladder)trans-111.6142.2172.3-61.9-175.911.900110.4H132 F158 K159 M160 Y245 V247H132-Q190 PolarHBondContact CE1-NE2 3.49Å; H132-Q190 PolarHBondContact ND1-NE2 3.09Å; H132-Q190 VanDerWaalsContact ND1-NE2 3.14Å; H132-Q190 PolarHBondContact NE2-NE2 3.46Å; F158-Q190 PolarHBondContact O-N 3.21Å; K159-Q190 WeakPolarHBondContact CA-O 3.29Å; K159-Q190 HydrophobicContact CB-CB 4.44Å; K159-Q190 HydrophobicContact CD-CB 3.9Å; M160-Q190 PolarHBondContact N-O 3.14Å; Q190-Y245 CarbonylContact C-O 3.44Å; Q190-Y245 WeakPolarHBondContact CA-O 3.48Å; Q190-Y245 HydrophobicContact CG-CD1 4.06Å; Q190-Y245 HydrophobicContact CG-CG 4.29Å; Q190-V247 HydrophobicContact CB-CG1 3.88Å; Q190-V247 HydrophobicContact CG-CG1 4.29Å
191V98.9Very high98.8Very high0 Ų025.5 Ų25.50%013%0.13CC..EExtended strand (participates in β ladder)trans-133.7132.2-177.2179.40000111.7K159 M160 M162 F179 A193 A233 L244 Y245 I246 V247K159-V191 PolarHBondContact NZ-O 3.31Å; M160-V191 HydrophobicContact CB-CG2 4.48Å; M160-V191 WeakPolarHBondContact O-CA 3.47Å; M162-V191 HydrophobicContact CG-CG1 3.8Å; M162-V191 HydrophobicContact SD-CG1 3.61Å; F179-V191 HydrophobicContact CE1-CG2 3.8Å; F179-V191 HydrophobicContact CZ-CG2 3.61Å; V191-A193 HydrophobicContact CG1-CB 4.04Å; V191-A233 HydrophobicContact CB-CB 4.45Å; V191-A233 HydrophobicContact CG1-CB 4.09Å; V191-A233 HydrophobicContact CG2-CB 4.38Å; V191-L244 HydrophobicContact CB-CD1 4.34Å; V191-L244 HydrophobicContact CG2-CD1 3.55Å; V191-Y245 PolarHBondContact N-O 2.67Å; V191-I246 HydrophobicContact CB-CD1 4.47Å; V191-V247 PolarHBondContact O-N 3.45Å
192H98.9Very high98.8Very high1 Ų125.9 Ų25.91%0.00514%0.136CC..EExtended strand (participates in β ladder)trans-85.1105.9161172.8108.4000105.8K159 M160 F161 M162 A163 Y164 E194 H248 G298K159-H192 VanDerWaalsContact NZ-CA 3.31Å; K159-H192 VanDerWaalsContact NZ-CB 3.3Å; M160-H192 PolarHBondContact O-N 3Å; F161-H192 HydrophobicContact CD1-CB 3.54Å; F161-H192 AromaticContact CD1-CG 3.89Å; F161-H192 HydrophobicContact CE1-CB 4.06Å; F161-H192 HydrophobicContact CG-CB 4.3Å; M162-H192 WeakPolarHBondContact CB-O 3.31Å; M162-H192 PolarHBondContact N-O 3.44Å; A163-H192 WeakPolarHBondContact CB-CD2 3.46Å; A163-H192 WeakPolarHBondContact CB-NE2 3.33Å; Y164-H192 AromaticContact CE2-CE1 3.88Å; H192-E194 IonicContact CE1-OE2 3.89Å; H192-E194 IonicContact NE2-OE2 3.54Å; H192-E194 PolarHBondContact NE2-OE2 3.39Å; H192-E194 VanDerWaalsContact NE2-OE2 3.14Å; H192-H248 AromaticContact CE1-CE1 3.78Å; H192-H248 AromaticContact CE1-NE2 3.8Å; H192-H248 AromaticContact CG-CE1 3.57Å; H192-H248 AromaticContact CG-NE2 3.65Å; H192-H248 AromaticContact ND1-CE1 3.03Å; H192-H248 PolarHBondContact ND1-CE1 3.47Å; H192-H248 AromaticContact ND1-NE2 2.86Å; H192-H248 PolarHBondContact ND1-NE2 3.11Å; H192-G298 PolarHBondContact CE1-O 3.2Å; H192-G298 VanDerWaalsContact CE1-O 3.3Å
193A98.8Very high98.8Very high3 Ų326.5 Ų26.53%0.02514%0.141CC..  trans-104.475.7-164.900000111.4M162 V191 E226 A229 T230 I246M162-A193 HydrophobicContact SD-CB 4.47Å; V191-A193 HydrophobicContact CG1-CB 4.04Å; A193-E226 VanDerWaalsContact O-CA 3.25Å; A193-E226 WeakPolarHBondContact O-CA 3.42Å; A193-E226 WeakPolarHBondContact O-CG 3.25Å; A193-E226 VanDerWaalsContact O-O 3.14Å; A193-A229 VanDerWaalsContact C-CB 3.41Å; A193-A229 HydrophobicContact CB-CB 4.21Å; A193-T230 WeakPolarHBondContact CB-OG1 3.4Å; A193-I246 HydrophobicContact CB-CG2 4.25Å
194E98.8Very high98.8Very high0 Ų030 Ų300%016%0.156CC..SBendtrans-127.3149.1162.9-55.1-174.191.200109.2M162 A163 H192 G196 I199 R221 V225 E226 A229 P299M162-E194 CarbonylContact C-O 3.42Å; M162-E194 VanDerWaalsContact CB-O 3.23Å; M162-E194 WeakPolarHBondContact CB-O 3.4Å; A163-E194 HydrophobicContact CB-CB 4.11Å; A163-E194 PolarHBondContact N-O 3.12Å; H192-E194 IonicContact CE1-OE2 3.89Å; H192-E194 IonicContact NE2-OE2 3.54Å; H192-E194 PolarHBondContact NE2-OE2 3.39Å; H192-E194 VanDerWaalsContact NE2-OE2 3.14Å; E194-G196 PolarHBondContact O-N 2.91Å; E194-G196 VanDerWaalsContact O-N 3.12Å; E194-I199 HydrophobicContact CB-CD1 3.42Å; E194-I199 VanDerWaalsContact CB-CD1 3.42Å; E194-I199 HydrophobicContact CB-CG1 4.5Å; E194-I199 HydrophobicContact CG-CD1 4.25Å; E194-R221 IonicContact OE2-NH1 2.93Å; E194-V225 HydrophobicContact CB-CG1 4.15Å; E194-E226 HydrophobicContact CG-CB 4.48Å; E194-A229 VanDerWaalsContact C-CB 3.42Å; E194-P299 VanDerWaalsContact CD-CB 3.49Å; E194-P299 HydrophobicContact CG-CB 3.99Å; E194-P299 HydrophobicContact CG-CG 3.71Å; E194-P299 WeakPolarHBondContact OE1-CB 3.33Å; E194-P299 WeakPolarHBondContact OE2-CA 3.43Å
195N98.8Very high98.8Very high22 Ų2230.2 Ų30.212%0.11816%0.155CC..  trans-74.7102.3176.3-171.1-49000111.2D197 L198 I199 V225 E228 R232N195-D197 VanDerWaalsContact C-N 3.32Å; N195-D197 PolarHBondContact O-N 3.31Å; N195-D197 PolarHBondContact OD1-N 3.4Å; N195-L198 HydrophobicContact CB-CB 4.16Å; N195-L198 HydrophobicContact CB-CD1 4.03Å; N195-L198 HydrophobicContact CB-CG 4.14Å; N195-L198 PolarHBondContact O-N 3Å; N195-L198 PolarHBondContact OD1-N 2.8Å; N195-L198 VanDerWaalsContact OD1-N 3.14Å; N195-I199 WeakPolarHBondContact O-CG1 3.4Å; N195-I199 PolarHBondContact O-N 3.21Å; N195-V225 HydrophobicContact CB-CG1 3.94Å; N195-V225 PolarHBondContact N-O 2.68Å; N195-V225 VanDerWaalsContact N-O 3.16Å; N195-E228 WeakPolarHBondContact CB-OE2 3.2Å; N195-E228 PolarHBondContact ND2-OE2 3.23Å; N195-R232 PolarHBondContact ND2-NH2 2.98Å
196G98.6Very high98.8Very high1 Ų130.4 Ų30.41%0.0116%0.156CC..Hα-helixtrans-62.1-30.9-175.500000115.6M162 E194 A200M162-G196 WeakPolarHBondContact O-CA 3.5Å; M162-G196 PolarHBondContact O-N 3.03Å; E194-G196 PolarHBondContact O-N 2.91Å; E194-G196 VanDerWaalsContact O-N 3.12Å; G196-A200 WeakPolarHBondContact O-CB 3.18Å; G196-A200 PolarHBondContact O-N 2.8Å; G196-A200 VanDerWaalsContact O-N 3.08Å
197D98.7Very high98.8Very high72 Ų7233 Ų3339%0.38517%0.168SC..Hα-helixtrans-69.5-44175.6-72.5-63.1000111.2K165 N195 A200 E201K165-D197 WeakPolarHBondContact CD-OD1 3.27Å; K165-D197 WeakPolarHBondContact CE-OD1 3.44Å; K165-D197 IonicContact NZ-OD1 2.97Å; K165-D197 PolarHBondContact NZ-OD1 3.03Å; N195-D197 VanDerWaalsContact C-N 3.32Å; N195-D197 PolarHBondContact O-N 3.31Å; N195-D197 PolarHBondContact OD1-N 3.4Å; D197-A200 PolarHBondContact O-N 3.08Å; D197-E201 PolarHBondContact O-N 3.47Å; D197-E201 VanDerWaalsContact O-N 3.08Å
198L98.8Very high98.7Very high92 Ų9237.1 Ų37.148%0.48220%0.203SC..Hα-helixtrans-66.7-37.6176.9-64.4-177.7000112.1N195 G202 V225N195-L198 HydrophobicContact CB-CB 4.16Å; N195-L198 HydrophobicContact CB-CD1 4.03Å; N195-L198 HydrophobicContact CB-CG 4.14Å; N195-L198 PolarHBondContact O-N 3Å; N195-L198 PolarHBondContact OD1-N 2.8Å; N195-L198 VanDerWaalsContact OD1-N 3.14Å; L198-G202 PolarHBondContact O-N 3.14Å; L198-V225 HydrophobicContact CB-CG2 4.28Å; L198-V225 HydrophobicContact CD1-CG2 4.34Å
199I98.6Very high98.7Very high15 Ų1542.4 Ų42.48%0.07723%0.231CC..Hα-helixtrans-60.1-47.4173.1-67.5166.5000110.5A163 E194 N195 E201 G202 A203 R221 V225A163-I199 HydrophobicContact CB-CD1 3.83Å; E194-I199 HydrophobicContact CB-CD1 3.42Å; E194-I199 VanDerWaalsContact CB-CD1 3.42Å; E194-I199 HydrophobicContact CB-CG1 4.5Å; E194-I199 HydrophobicContact CG-CD1 4.25Å; N195-I199 WeakPolarHBondContact O-CG1 3.4Å; N195-I199 PolarHBondContact O-N 3.21Å; I199-E201 PolarHBondContact O-N 3.3Å; I199-G202 PolarHBondContact O-N 3.09Å; I199-A203 WeakPolarHBondContact O-CB 3.39Å; I199-A203 PolarHBondContact O-N 3.21Å; I199-R221 HydrophobicContact CG1-CB 3.85Å; I199-V225 HydrophobicContact CD1-CG1 4.36Å; I199-V225 HydrophobicContact CG1-CG1 3.92Å
200A98.6Very high98.7Very high25 Ų2545 Ų4521%0.20726%0.258CS..Hα-helixtrans-61.9-44.5-177.800000111.8K165 G196 D197 K204K165-A200 HydrophobicContact CB-CB 4.5Å; K165-A200 HydrophobicContact CD-CB 4.07Å; G196-A200 WeakPolarHBondContact O-CB 3.18Å; G196-A200 PolarHBondContact O-N 2.8Å; G196-A200 VanDerWaalsContact O-N 3.08Å; D197-A200 PolarHBondContact O-N 3.08Å; A200-K204 VanDerWaalsContact O-CG 3.3Å; A200-K204 WeakPolarHBondContact O-CG 3.34Å; A200-K204 PolarHBondContact O-N 3.08Å
201E98.6Very high98.7Very high101 Ų10147.1 Ų47.147%0.47227%0.269SS..Hα-helixtrans-70.6-38.8176.5-66.6-52.8128.700112.5D197 I199 A203 K204 K205D197-E201 PolarHBondContact O-N 3.47Å; D197-E201 VanDerWaalsContact O-N 3.08Å; I199-E201 PolarHBondContact O-N 3.3Å; E201-A203 VanDerWaalsContact C-N 3.34Å; E201-A203 PolarHBondContact O-N 2.91Å; E201-K204 PolarHBondContact O-N 2.81Å; E201-K204 IonicContact OE1-NZ 3.51Å; E201-K204 PolarHBondContact OE1-NZ 2.52Å; E201-K205 WeakPolarHBondContact O-CB 3.43Å; E201-K205 PolarHBondContact O-N 2.73Å
202G98.7Very high98.7Very high14 Ų1449.9 Ų49.914%0.14429%0.285CS..Hα-helixtrans-59.6-44174.500000112L198 I199 K205 M206 C220L198-G202 PolarHBondContact O-N 3.14Å; I199-G202 PolarHBondContact O-N 3.09Å; G202-K205 WeakPolarHBondContact O-CB 3.23Å; G202-K205 PolarHBondContact O-N 2.84Å; G202-M206 WeakPolarHBondContact O-CG 3.27Å; G202-M206 PolarHBondContact O-N 3.39Å; G202-C220 VanDerWaalsContact C-CB 3.45Å
203A98.6Very high98.7Very high12 Ų1250.2 Ų50.210%0.09929%0.289CS..Hα-helixtrans-66.1-45.4-179.600000111.5I199 E201 K205 M206 L207 C220 F342 T343I199-A203 WeakPolarHBondContact O-CB 3.39Å; I199-A203 PolarHBondContact O-N 3.21Å; E201-A203 VanDerWaalsContact C-N 3.34Å; E201-A203 PolarHBondContact O-N 2.91Å; A203-K205 VanDerWaalsContact C-N 3.28Å; A203-K205 PolarHBondContact O-N 3.33Å; A203-M206 PolarHBondContact O-N 3.37Å; A203-L207 WeakPolarHBondContact O-CG 3.15Å; A203-L207 PolarHBondContact O-N 2.93Å; A203-L207 VanDerWaalsContact O-N 3.07Å; A203-C220 HydrophobicContact CB-CB 4.27Å; A203-F342 HydrophobicContact CB-CE2 4.45Å; A203-F342 HydrophobicContact CB-CZ 4.2Å; A203-T343 HydrophobicContact CB-CG2 4.02Å
204K98.6Very high98.7Very high123 Ų12350.2 Ų50.254%0.53529%0.289SS..Hα-helixtrans-56-44.6172.6-69.8170.7-169.7172.90111.4A200 E201 A208A200-K204 VanDerWaalsContact O-CG 3.3Å; A200-K204 WeakPolarHBondContact O-CG 3.34Å; A200-K204 PolarHBondContact O-N 3.08Å; E201-K204 PolarHBondContact O-N 2.81Å; E201-K204 IonicContact OE1-NZ 3.51Å; E201-K204 PolarHBondContact OE1-NZ 2.52Å; K204-A208 VanDerWaalsContact O-CB 3.31Å; K204-A208 WeakPolarHBondContact O-CB 3.44Å; K204-A208 PolarHBondContact O-N 3.18Å
205K98.8Very high98.7Very high134 Ų13452.7 Ų52.758%0.58330%0.3SS*.Hα-helixtrans-62.7-46.7178.9-176.7-175.2175.2-175.90111.9E201 G202 A203 A208 L209E201-K205 WeakPolarHBondContact O-CB 3.43Å; E201-K205 PolarHBondContact O-N 2.73Å; G202-K205 WeakPolarHBondContact O-CB 3.23Å; G202-K205 PolarHBondContact O-N 2.84Å; A203-K205 VanDerWaalsContact C-N 3.28Å; A203-K205 PolarHBondContact O-N 3.33Å; K205-A208 PolarHBondContact O-N 2.93Å; K205-L209 HydrophobicContact CG-CD1 4.23Å; K205-L209 WeakPolarHBondContact O-CG 3.25Å; K205-L209 PolarHBondContact O-N 3.39Å; K205-L209 VanDerWaalsContact O-N 3.09Å
206M98.8Very high98.7Very high19 Ų1951.6 Ų51.69%0.09430%0.295CS..Hα-helixtrans-61.3-46.5179.7-68.6-50.5103.800111.3G202 A203 A208 L209 G210 I211 L219 C220 F342G202-M206 WeakPolarHBondContact O-CG 3.27Å; G202-M206 PolarHBondContact O-N 3.39Å; A203-M206 PolarHBondContact O-N 3.37Å; M206-A208 PolarHBondContact O-N 2.78Å; M206-L209 HydrophobicContact CE-CD1 4.22Å; M206-L209 PolarHBondContact O-N 3.49Å; M206-L209 VanDerWaalsContact O-N 3.14Å; M206-G210 PolarHBondContact O-N 3.17Å; M206-I211 CarbonylContact C-O 3.48Å; M206-I211 HydrophobicContact CB-CB 4.3Å; M206-I211 WeakPolarHBondContact O-CB 3.25Å; M206-I211 PolarHBondContact O-N 3.17Å; M206-I211 HydrophobicContact SD-CD1 3.87Å; M206-L219 HydrophobicContact CG-CB 4.21Å; M206-L219 HydrophobicContact SD-CB 3.63Å; M206-L219 HydrophobicContact SD-CD1 4.35Å; M206-C220 HydrophobicContact CG-CB 3.9Å; M206-F342 HydrophobicContact CB-CE1 3.82Å; M206-F342 HydrophobicContact CB-CZ 3.98Å
207L98.8Very high98.7Very high55 Ų5551.6 Ų51.629%0.28830%0.295SS..Hα-helixtrans-62.6-41.2176.8-67.7174.9000112.4A203 L209 G210 T212 F342 T343A203-L207 WeakPolarHBondContact O-CG 3.15Å; A203-L207 PolarHBondContact O-N 2.93Å; A203-L207 VanDerWaalsContact O-N 3.07Å; L207-L209 PolarHBondContact O-N 2.66Å; L207-G210 PolarHBondContact O-N 3.05Å; L207-T212 HydrophobicContact CD2-CG2 4.13Å; L207-F342 HydrophobicContact CD2-CD1 4.12Å; L207-F342 HydrophobicContact CD2-CE1 3.9Å; L207-F342 HydrophobicContact CG-CE1 4.08Å; L207-T343 HydrophobicContact CD1-CG2 3.89Å; L207-T343 HydrophobicContact CG-CG2 4.46Å
208A98.7Very high98.7Very high88 Ų8849 Ų4973%0.72728%0.28SS*.Hα-helixtrans-64.6-25.3176.900000113.3K204 K205 M206 G210K204-A208 VanDerWaalsContact O-CB 3.31Å; K204-A208 WeakPolarHBondContact O-CB 3.44Å; K204-A208 PolarHBondContact O-N 3.18Å; K205-A208 PolarHBondContact O-N 2.93Å; M206-A208 PolarHBondContact O-N 2.78Å; A208-G210 VanDerWaalsContact C-N 3.26Å
209L98.7Very high98.7Very high114 Ų11448 Ų4860%0.59728%0.275SS*.THydrogen-bonded Turntrans-830.7172.6-67.5171.7000113.1K205 M206 L207 I211K205-L209 HydrophobicContact CG-CD1 4.23Å; K205-L209 WeakPolarHBondContact O-CG 3.25Å; K205-L209 PolarHBondContact O-N 3.39Å; K205-L209 VanDerWaalsContact O-N 3.09Å; M206-L209 HydrophobicContact CE-CD1 4.22Å; M206-L209 PolarHBondContact O-N 3.49Å; M206-L209 VanDerWaalsContact O-N 3.14Å; L207-L209 PolarHBondContact O-N 2.66Å; L209-I211 VanDerWaalsContact C-N 3.3Å; L209-I211 HydrophobicContact CB-CD1 4.32Å; L209-I211 HydrophobicContact CB-CG1 4.33Å
210G98.6Very high98.7Very high55 Ų5547.4 Ų47.457%0.56727%0.272SS*.THydrogen-bonded Turntrans78.510.6-176.400000114.2M206 L207 A208 T212M206-G210 PolarHBondContact O-N 3.17Å; L207-G210 PolarHBondContact O-N 3.05Å; A208-G210 VanDerWaalsContact C-N 3.26Å; G210-T212 PolarHBondContact O-N 3.22Å
211I98.8Very high98.7Very high44 Ų4447.1 Ų47.123%0.22627%0.266CS..  trans-84.599.4175.7-56.9170.7000107.7M206 L209 E215 L219M206-I211 CarbonylContact C-O 3.48Å; M206-I211 HydrophobicContact CB-CB 4.3Å; M206-I211 WeakPolarHBondContact O-CB 3.25Å; M206-I211 PolarHBondContact O-N 3.17Å; M206-I211 HydrophobicContact SD-CD1 3.87Å; L209-I211 VanDerWaalsContact C-N 3.3Å; L209-I211 HydrophobicContact CB-CD1 4.32Å; L209-I211 HydrophobicContact CB-CG1 4.33Å; I211-E215 HydrophobicContact CG2-CG 4.11Å; I211-L219 HydrophobicContact CD1-CD1 4.3Å; I211-L219 HydrophobicContact CG2-CD1 4.44Å
212T98.8Very high98.6Very high57 Ų5745.1 Ų45.135%0.3526%0.261SS..  trans-111.8-11-177.2580000113.6L207 G210 D340 F342L207-T212 HydrophobicContact CD2-CG2 4.13Å; G210-T212 PolarHBondContact O-N 3.22Å; T212-D340 VanDerWaalsContact CB-O 3.31Å; T212-D340 WeakPolarHBondContact CB-O 3.48Å; T212-D340 WeakPolarHBondContact CG2-O 3.44Å; T212-F342 PolarHBondContact O-N 2.82Å
213G98.8Very high98.6Very high9 Ų947.5 Ų47.59%0.09327%0.269CS..SBendtrans-77.9170.3179.500000113.6E215 G216 F342G213-E215 VanDerWaalsContact CA-OE2 3.27Å; G213-E215 WeakPolarHBondContact CA-OE2 3.37Å; G213-E215 PolarHBondContact O-N 3.37Å; G213-E215 VanDerWaalsContact O-N 3.12Å; G213-G216 PolarHBondContact O-N 3.18Å; G213-F342 VanDerWaalsContact O-CB 3.29Å; G213-F342 WeakPolarHBondContact O-CB 3.38Å
214P98.8Very high98.6Very high3 Ų350.1 Ų50.12%0.01929%0.291CS..THydrogen-bonded Turntrans-54.6-28-178.3-2838.1000114.9G216 H217 Y284 A292 A293 V296 I345P214-G216 PolarHBondContact O-N 2.78Å; P214-H217 WeakPolarHBondContact O-CB 3.38Å; P214-H217 PolarHBondContact O-N 2.83Å; P214-Y284 HydrophobicContact CB-CD1 4.42Å; P214-A292 HydrophobicContact CB-CB 3.86Å; P214-A292 HydrophobicContact CG-CB 3.75Å; P214-A293 HydrophobicContact CG-CB 4.08Å; P214-V296 HydrophobicContact CB-CG2 3.82Å; P214-I345 HydrophobicContact CB-CD1 4.43Å; P214-I345 HydrophobicContact CG-CD1 4.03Å
215E98.8Very high98.6Very high51 Ų5144.8 Ų44.824%0.23827%0.268CS..Hα-helixtrans-59.1-30.9173.172.3-68.8168.200113I211 G213 H217 E218 L219 W285I211-E215 HydrophobicContact CG2-CG 4.11Å; G213-E215 VanDerWaalsContact CA-OE2 3.27Å; G213-E215 WeakPolarHBondContact CA-OE2 3.37Å; G213-E215 PolarHBondContact O-N 3.37Å; G213-E215 VanDerWaalsContact O-N 3.12Å; E215-H217 PolarHBondContact O-N 3.44Å; E215-E218 PolarHBondContact O-N 2.78Å; E215-L219 HydrophobicContact CG-CD1 4.38Å; E215-L219 VanDerWaalsContact O-CG 3.25Å; E215-L219 WeakPolarHBondContact O-CG 3.36Å; E215-L219 PolarHBondContact O-N 3.34Å; E215-W285 HydrophobicContact CB-CD2 4.25Å; E215-W285 HydrophobicContact CB-CG 4.43Å; E215-W285 HydrophobicContact CB-CZ2 4.28Å
216G98.8Very high98.7Very high0 Ų038.5 Ų38.50%024%0.241CC..Hα-helixtrans-60.3-27.7172.900000112.8G213 P214 C220 F342G213-G216 PolarHBondContact O-N 3.18Å; P214-G216 PolarHBondContact O-N 2.78Å; G216-C220 VanDerWaalsContact O-CB 3.3Å; G216-C220 WeakPolarHBondContact O-CB 3.37Å; G216-C220 PolarHBondContact O-N 2.92Å; G216-C220 PolarHBondContact O-SG 3.14Å; G216-C220 VanDerWaalsContact O-SG 3.37Å; G216-F342 WeakPolarHBondContact O-CE2 3.45Å; G216-F342 WeakPolarHBondContact O-CZ 3.29Å
217H98.6Very high98.7Very high1 Ų138.2 Ų38.21%0.00524%0.242CC..Hα-helixtrans-67.3-41.1177.3-173.271.3000112.3P214 E215 C220 R221 V296 M297 F342 N347P214-H217 WeakPolarHBondContact O-CB 3.38Å; P214-H217 PolarHBondContact O-N 2.83Å; E215-H217 PolarHBondContact O-N 3.44Å; H217-C220 PolarHBondContact O-SG 3.28Å; H217-R221 PolarHBondContact CE1-NH1 3.39Å; H217-R221 PolarHBondContact CE1-NH2 3.33Å; H217-R221 VanDerWaalsContact CE1-NH2 3.34Å; H217-R221 PolarHBondContact ND1-NH2 2.87Å; H217-R221 WeakPolarHBondContact O-CD 3.28Å; H217-R221 VanDerWaalsContact O-CG 3.24Å; H217-R221 WeakPolarHBondContact O-CG 3.23Å; H217-R221 PolarHBondContact O-NE 3.42Å; H217-V296 HydrophobicContact CB-CG1 4.49Å; H217-M297 PolarHBondContact CD2-O 3.04Å; H217-M297 PolarHBondContact NE2-O 3.16Å; H217-F342 VanDerWaalsContact CA-CD2 3.46Å; H217-F342 HydrophobicContact CB-CD2 3.7Å; H217-F342 HydrophobicContact CB-CE2 4.3Å; H217-F342 HydrophobicContact CB-CG 4.4Å; H217-N347 PolarHBondContact CE1-OD1 2.68Å; H217-N347 PolarHBondContact NE2-OD1 2.77Å; H217-N347 VanDerWaalsContact NE2-OD1 3.15Å
218E98.5Very high98.7Very high17 Ų1738.9 Ų38.98%0.07924%0.243CC..Hα-helixtrans-71-48.9174-166-73.3150.800110.8E215 C220 R221 Y284 W285 P300 P303E215-E218 PolarHBondContact O-N 2.78Å; E218-C220 PolarHBondContact O-N 2.85Å; E218-C220 VanDerWaalsContact O-N 3.16Å; E218-R221 CarbonylContact O-C 3.56Å; E218-R221 PolarHBondContact O-N 2.92Å; E218-Y284 HydrophobicContact CB-CD2 3.8Å; E218-Y284 HydrophobicContact CB-CE2 4.15Å; E218-Y284 HydrophobicContact CG-CD2 4.13Å; E218-Y284 HydrophobicContact CG-CE2 4.31Å; E218-W285 HydrophobicContact CB-CH2 4.04Å; E218-W285 HydrophobicContact CG-CH2 3.97Å; E218-W285 HydrophobicContact CG-CZ3 4.4Å; E218-W285 WeakPolarHBondContact OE2-CH2 3.46Å; E218-P300 HydrophobicContact CB-CB 4.41Å; E218-P300 HydrophobicContact CG-CB 4.38Å; E218-P300 HydrophobicContact CG-CG 4.28Å; E218-P303 HydrophobicContact CG-CG 4.4Å; E218-P303 VanDerWaalsContact OE1-CD 3.32Å; E218-P303 WeakPolarHBondContact OE1-CD 3.49Å
219L98.7Very high98.7Very high70 Ų7034.7 Ų34.737%0.36621%0.209SC..Hα-helixtrans-62.4-27.8-174.7-68.3171.1000113.5M206 I211 E215 R221 W285M206-L219 HydrophobicContact CG-CB 4.21Å; M206-L219 HydrophobicContact SD-CB 3.63Å; M206-L219 HydrophobicContact SD-CD1 4.35Å; I211-L219 HydrophobicContact CD1-CD1 4.3Å; I211-L219 HydrophobicContact CG2-CD1 4.44Å; E215-L219 HydrophobicContact CG-CD1 4.38Å; E215-L219 VanDerWaalsContact O-CG 3.25Å; E215-L219 WeakPolarHBondContact O-CG 3.36Å; E215-L219 PolarHBondContact O-N 3.34Å; L219-R221 VanDerWaalsContact C-N 3.31Å; L219-W285 HydrophobicContact CD2-CZ2 4.23Å; L219-W285 HydrophobicContact CG-CZ2 4.31Å
220C98.4Very high98.7Very high4 Ų429.3 Ų29.33%0.02718%0.18CC..THydrogen-bonded Turntrans-77.4-14.3177.3750000114.3G202 A203 M206 G216 H217 E218 F342G202-C220 VanDerWaalsContact C-CB 3.45Å; A203-C220 HydrophobicContact CB-CB 4.27Å; M206-C220 HydrophobicContact CG-CB 3.9Å; G216-C220 VanDerWaalsContact O-CB 3.3Å; G216-C220 WeakPolarHBondContact O-CB 3.37Å; G216-C220 PolarHBondContact O-N 2.92Å; G216-C220 PolarHBondContact O-SG 3.14Å; G216-C220 VanDerWaalsContact O-SG 3.37Å; H217-C220 PolarHBondContact O-SG 3.28Å; E218-C220 PolarHBondContact O-N 2.85Å; E218-C220 VanDerWaalsContact O-N 3.16Å; C220-F342 HydrophobicContact CB-CE2 4.44Å; C220-F342 HydrophobicContact CB-CZ 4.26Å
221R98.2Very high98.7Very high18 Ų1830.8 Ų30.87%0.06818%0.175CC..SBendtrans-143.659.8-173.968.5-166.766.4-164.78.1112E194 I199 H217 E218 L219 P300 R302E194-R221 IonicContact OE2-NH1 2.93Å; I199-R221 HydrophobicContact CG1-CB 3.85Å; H217-R221 PolarHBondContact CE1-NH1 3.39Å; H217-R221 PolarHBondContact CE1-NH2 3.33Å; H217-R221 VanDerWaalsContact CE1-NH2 3.34Å; H217-R221 PolarHBondContact ND1-NH2 2.87Å; H217-R221 WeakPolarHBondContact O-CD 3.28Å; H217-R221 VanDerWaalsContact O-CG 3.24Å; H217-R221 WeakPolarHBondContact O-CG 3.23Å; H217-R221 PolarHBondContact O-NE 3.42Å; E218-R221 CarbonylContact O-C 3.56Å; E218-R221 PolarHBondContact O-N 2.92Å; L219-R221 VanDerWaalsContact C-N 3.31Å; R221-P300 HydrophobicContact CG-CG 3.65Å; R221-R302 PolarHBondContact O-NH1 3.48Å
222P98.3Very high98.7Very high59 Ų5930.9 Ų30.938%0.38317%0.172SC..  trans-58.6158.7179.927.7-36.6000111.2A224 V225P222-A224 PolarHBondContact O-N 3.3Å; P222-V225 HydrophobicContact CG-CG2 4.17Å; P222-V225 VanDerWaalsContact O-CB 3.25Å; P222-V225 WeakPolarHBondContact O-CB 3.46Å; P222-V225 PolarHBondContact O-N 3.05Å
223E98.5Very high98.7Very high64 Ų6428.1 Ų28.130%0.29916%0.156SC..Hα-helixtrans-56.1-25.2-170.258.5160.3-118.700115.8V225 E226 A227 S251 S253E223-V225 PolarHBondContact O-N 3.19Å; E223-E226 WeakPolarHBondContact O-CB 3.45Å; E223-E226 PolarHBondContact O-N 3.33Å; E223-A227 PolarHBondContact O-N 3.31Å; E223-S251 VanDerWaalsContact CB-CB 3.45Å; E223-S253 WeakPolarHBondContact OE1-CB 3.35Å; E223-S253 PolarHBondContact OE1-OG 3.39Å
224A98.8Very high98.7Very high68 Ų6827.8 Ų27.856%0.56215%0.152SC*.Hα-helixtrans-58.6-29.7173.100000113.4P222 E226 A227 E228P222-A224 PolarHBondContact O-N 3.3Å; A224-E226 VanDerWaalsContact C-N 3.34Å; A224-A227 PolarHBondContact O-N 2.91Å; A224-E228 WeakPolarHBondContact O-CB 3.41Å; A224-E228 PolarHBondContact O-N 3.43Å
225V98.7Very high98.7Very high10 Ų1031.4 Ų31.46%0.06117%0.174CC..Hα-helixtrans-67.4-35.4175.7173.50000111.4E194 N195 L198 I199 P222 E223E194-V225 HydrophobicContact CB-CG1 4.15Å; N195-V225 HydrophobicContact CB-CG1 3.94Å; N195-V225 PolarHBondContact N-O 2.68Å; N195-V225 VanDerWaalsContact N-O 3.16Å; L198-V225 HydrophobicContact CB-CG2 4.28Å; L198-V225 HydrophobicContact CD1-CG2 4.34Å; I199-V225 HydrophobicContact CD1-CG1 4.36Å; I199-V225 HydrophobicContact CG1-CG1 3.92Å; P222-V225 HydrophobicContact CG-CG2 4.17Å; P222-V225 VanDerWaalsContact O-CB 3.25Å; P222-V225 WeakPolarHBondContact O-CB 3.46Å; P222-V225 PolarHBondContact O-N 3.05Å; E223-V225 PolarHBondContact O-N 3.19Å
226E98.9Very high98.7Very high3 Ų329.9 Ų29.91%0.01417%0.167CC..Hα-helixtrans-74.8-44.2174.8-171.9-167.9173.700110.8A193 E194 E223 A224 E228 A229 T230 M250 S251 A254 P299 R302A193-E226 VanDerWaalsContact O-CA 3.25Å; A193-E226 WeakPolarHBondContact O-CA 3.42Å; A193-E226 WeakPolarHBondContact O-CG 3.25Å; A193-E226 VanDerWaalsContact O-O 3.14Å; E194-E226 HydrophobicContact CG-CB 4.48Å; E223-E226 WeakPolarHBondContact O-CB 3.45Å; E223-E226 PolarHBondContact O-N 3.33Å; A224-E226 VanDerWaalsContact C-N 3.34Å; E226-E228 PolarHBondContact O-N 2.84Å; E226-A229 PolarHBondContact O-N 3.24Å; E226-T230 VanDerWaalsContact O-CB 3.29Å; E226-T230 WeakPolarHBondContact O-CB 3.22Å; E226-T230 PolarHBondContact O-N 2.88Å; E226-T230 PolarHBondContact O-OG1 2.98Å; E226-M250 PolarHBondContact OE1-N 3.24Å; E226-S251 VanDerWaalsContact CD-OG 3.27Å; E226-S251 WeakPolarHBondContact OE2-CB 3.35Å; E226-S251 PolarHBondContact OE2-N 2.9Å; E226-S251 PolarHBondContact OE2-OG 3.47Å; E226-A254 HydrophobicContact CB-CB 4.41Å; E226-A254 HydrophobicContact CG-CB 3.73Å; E226-P299 HydrophobicContact CG-CG 4.28Å; E226-R302 IonicContact OE2-CZ 2.79Å; E226-R302 IonicContact OE2-NE 2.77Å; E226-R302 IonicContact OE2-NH2 3.85Å; E226-R302 PolarHBondContact OE2-NH2 2.81Å
227A98.9Very high98.7Very high13 Ų1330 Ų3011%0.10717%0.168CC..Hα-helixtrans-63.5-42.4-179.200000113E223 A224 T230 L231 V257E223-A227 PolarHBondContact O-N 3.31Å; A224-A227 PolarHBondContact O-N 2.91Å; A227-T230 PolarHBondContact O-N 3.08Å; A227-L231 PolarHBondContact O-N 3.38Å; A227-V257 HydrophobicContact CB-CG2 4.42Å
228E98.9Very high98.7Very high69 Ų6932 Ų3232%0.32218%0.182SC..Hα-helixtrans-59.2-52.9176.1-177-78.7137.900111.3N195 A224 E226 T230 L231 R232N195-E228 WeakPolarHBondContact CB-OE2 3.2Å; N195-E228 PolarHBondContact ND2-OE2 3.23Å; A224-E228 WeakPolarHBondContact O-CB 3.41Å; A224-E228 PolarHBondContact O-N 3.43Å; E226-E228 PolarHBondContact O-N 2.84Å; E228-T230 VanDerWaalsContact C-N 3.29Å; E228-T230 PolarHBondContact O-N 3.34Å; E228-L231 PolarHBondContact O-N 2.66Å; E228-R232 WeakPolarHBondContact O-CB 3.45Å; E228-R232 PolarHBondContact O-N 3.47Å; E228-R232 IonicContact OE1-CZ 2.88Å; E228-R232 IonicContact OE1-NE 3.83Å; E228-R232 PolarHBondContact OE1-NE 3.46Å; E228-R232 IonicContact OE1-NH2 2.81Å; E228-R232 IonicContact OE2-CZ 3.58Å; E228-R232 IonicContact OE2-NE 3.8Å; E228-R232 IonicContact OE2-NH2 3.9Å; E228-R232 PolarHBondContact OE2-NH2 2.67Å
229A98.9Very high98.7Very high0 Ų034.7 Ų34.70%021%0.207CC..Hα-helixtrans-64.6-36-178.600000111.7M162 A193 E194 E226 R232 A233M162-A229 HydrophobicContact CB-CB 4.48Å; M162-A229 HydrophobicContact CE-CB 3.71Å; M162-A229 WeakPolarHBondContact CE-O 3.45Å; M162-A229 HydrophobicContact SD-CB 3.95Å; M162-A229 VanDerWaalsContact SD-O 3.4Å; A193-A229 VanDerWaalsContact C-CB 3.41Å; A193-A229 HydrophobicContact CB-CB 4.21Å; E194-A229 VanDerWaalsContact C-CB 3.42Å; E226-A229 PolarHBondContact O-N 3.24Å; A229-R232 PolarHBondContact O-N 2.85Å; A229-A233 WeakPolarHBondContact O-CB 3.49Å; A229-A233 PolarHBondContact O-N 3.22Å
230T98.9Very high98.7Very high0 Ų032.2 Ų32.20%020%0.195CC..Hα-helixtrans-60.2-48.5174-63.30000111.1A193 E226 A227 E228 R232 A233 I234 I246 V257 I258A193-T230 WeakPolarHBondContact CB-OG1 3.4Å; E226-T230 VanDerWaalsContact O-CB 3.29Å; E226-T230 WeakPolarHBondContact O-CB 3.22Å; E226-T230 PolarHBondContact O-N 2.88Å; E226-T230 PolarHBondContact O-OG1 2.98Å; A227-T230 PolarHBondContact O-N 3.08Å; E228-T230 VanDerWaalsContact C-N 3.29Å; E228-T230 PolarHBondContact O-N 3.34Å; T230-R232 PolarHBondContact O-N 3.27Å; T230-A233 PolarHBondContact O-N 3.01Å; T230-I234 HydrophobicContact CG2-CD1 3.89Å; T230-I234 WeakPolarHBondContact O-CB 3.28Å; T230-I234 WeakPolarHBondContact O-CD1 3.44Å; T230-I234 VanDerWaalsContact O-CG1 3.26Å; T230-I234 WeakPolarHBondContact O-CG1 3.44Å; T230-I234 PolarHBondContact O-N 2.73Å; T230-I246 HydrophobicContact CG2-CD1 4.33Å; T230-I246 HydrophobicContact CG2-CG1 4.15Å; T230-I246 HydrophobicContact CG2-CG2 4.39Å; T230-V257 HydrophobicContact CG2-CB 4.18Å; T230-V257 HydrophobicContact CG2-CG1 3.82Å; T230-I258 HydrophobicContact CG2-CD1 4.3Å; T230-I258 HydrophobicContact CG2-CG1 3.81Å
231L98.9Very high98.7Very high87 Ų8732.7 Ų32.746%0.45520%0.197SC..Hα-helixtrans-62.8-43.6177.7177.360.4000111.6A227 E228 I234 T235 V257A227-L231 PolarHBondContact O-N 3.38Å; E228-L231 PolarHBondContact O-N 2.66Å; L231-I234 PolarHBondContact O-N 2.58Å; L231-T235 WeakPolarHBondContact O-CB 3.38Å; L231-T235 PolarHBondContact O-N 2.99Å; L231-T235 PolarHBondContact O-OG1 3.19Å; L231-V257 HydrophobicContact CB-CG1 3.77Å; L231-V257 HydrophobicContact CD1-CG1 4.17Å
232R98.9Very high98.7Very high45 Ų4532 Ų3217%0.1720%0.196CC..Hα-helixtrans-63.5-46.3178.8176.2157.449.7103.1-0.3111.7M162 D172 N195 E228 A229 T230 I234 T235 I236M162-R232 HydrophobicContact CE-CB 4.1Å; M162-R232 HydrophobicContact CE-CG 4Å; D172-R232 IonicContact OD1-CZ 3.37Å; D172-R232 IonicContact OD1-NH1 2.98Å; D172-R232 PolarHBondContact OD1-NH1 3.24Å; D172-R232 IonicContact OD2-NH1 3.75Å; N195-R232 PolarHBondContact ND2-NH2 2.98Å; E228-R232 WeakPolarHBondContact O-CB 3.45Å; E228-R232 PolarHBondContact O-N 3.47Å; E228-R232 IonicContact OE1-CZ 2.88Å; E228-R232 IonicContact OE1-NE 3.83Å; E228-R232 PolarHBondContact OE1-NE 3.46Å; E228-R232 IonicContact OE1-NH2 2.81Å; E228-R232 IonicContact OE2-CZ 3.58Å; E228-R232 IonicContact OE2-NE 3.8Å; E228-R232 IonicContact OE2-NH2 3.9Å; E228-R232 PolarHBondContact OE2-NH2 2.67Å; A229-R232 PolarHBondContact O-N 2.85Å; T230-R232 PolarHBondContact O-N 3.27Å; R232-I234 PolarHBondContact O-N 3.3Å; R232-T235 WeakPolarHBondContact O-CB 3.47Å; R232-T235 PolarHBondContact O-N 2.79Å; R232-I236 HydrophobicContact CG-CD1 3.96Å; R232-I236 WeakPolarHBondContact O-CG1 3.33Å; R232-I236 PolarHBondContact O-N 2.87Å
233A98.9Very high98.8Very high0 Ų029.2 Ų29.20%018%0.177CC..Hα-helixtrans-58.4-46.7175.200000112M162 V191 A229 T230 T235 I236 A237 L244 I246M162-A233 HydrophobicContact SD-CB 3.8Å; V191-A233 HydrophobicContact CB-CB 4.45Å; V191-A233 HydrophobicContact CG1-CB 4.09Å; V191-A233 HydrophobicContact CG2-CB 4.38Å; A229-A233 WeakPolarHBondContact O-CB 3.49Å; A229-A233 PolarHBondContact O-N 3.22Å; T230-A233 PolarHBondContact O-N 3.01Å; A233-T235 VanDerWaalsContact C-N 3.29Å; A233-T235 PolarHBondContact O-N 2.96Å; A233-I236 PolarHBondContact O-N 3.5Å; A233-A237 WeakPolarHBondContact O-CB 3.38Å; A233-A237 PolarHBondContact O-N 2.97Å; A233-L244 VanDerWaalsContact C-CD2 3.48Å; A233-L244 HydrophobicContact CB-CD2 3.92Å; A233-I246 HydrophobicContact CB-CD1 4.36Å
234I98.9Very high98.8Very high2 Ų226.3 Ų26.31%0.0116%0.164CC..Hα-helixtrans-59.7-41.1177-73.3167000111.3T230 L231 R232 S238 L244 V257 I258 A261 K266 V268T230-I234 HydrophobicContact CG2-CD1 3.89Å; T230-I234 WeakPolarHBondContact O-CB 3.28Å; T230-I234 WeakPolarHBondContact O-CD1 3.44Å; T230-I234 VanDerWaalsContact O-CG1 3.26Å; T230-I234 WeakPolarHBondContact O-CG1 3.44Å; T230-I234 PolarHBondContact O-N 2.73Å; L231-I234 PolarHBondContact O-N 2.58Å; R232-I234 PolarHBondContact O-N 3.3Å; I234-S238 VanDerWaalsContact O-CB 3.26Å; I234-S238 WeakPolarHBondContact O-CB 3.47Å; I234-S238 PolarHBondContact O-N 2.62Å; I234-S238 PolarHBondContact O-OG 2.86Å; I234-L244 HydrophobicContact CB-CD2 4.3Å; I234-L244 HydrophobicContact CG1-CD2 3.72Å; I234-V257 HydrophobicContact CD1-CG1 3.92Å; I234-I258 HydrophobicContact CD1-CG1 4.34Å; I234-A261 HydrophobicContact CD1-CB 3.94Å; I234-A261 HydrophobicContact CG2-CB 3.79Å; I234-K266 HydrophobicContact CG2-CD 3.57Å; I234-V268 HydrophobicContact CD1-CG1 4.45Å; I234-V268 HydrophobicContact CD1-CG2 4.02Å; I234-V268 HydrophobicContact CG1-CB 4.36Å; I234-V268 HydrophobicContact CG1-CG2 3.87Å
235T98.9Very high98.8Very high78 Ų7823 Ų2348%0.47914%0.137SC..Hα-helixtrans-64-48.3179.5-59.50000111L231 R232 A233 S238 A239L231-T235 WeakPolarHBondContact O-CB 3.38Å; L231-T235 PolarHBondContact O-N 2.99Å; L231-T235 PolarHBondContact O-OG1 3.19Å; R232-T235 WeakPolarHBondContact O-CB 3.47Å; R232-T235 PolarHBondContact O-N 2.79Å; A233-T235 VanDerWaalsContact C-N 3.29Å; A233-T235 PolarHBondContact O-N 2.96Å; T235-S238 PolarHBondContact O-N 2.73Å; T235-A239 PolarHBondContact O-N 2.94Å
236I98.9Very high98.8Very high20 Ų2022.6 Ų22.610%0.10313%0.134CC..Hα-helixtrans-63.8-46.7178.5-60.7165.9000110.4D172 L175 Y176 F179 R232 A233 S238 A239 V240D172-I236 HydrophobicContact CB-CD1 4.02Å; L175-I236 HydrophobicContact CB-CD1 4.31Å; L175-I236 HydrophobicContact CB-CG2 4.43Å; L175-I236 HydrophobicContact CD1-CD1 4.15Å; Y176-I236 HydrophobicContact CD2-CG2 4.3Å; F179-I236 HydrophobicContact CD2-CB 4.18Å; F179-I236 HydrophobicContact CD2-CG2 3.69Å; F179-I236 HydrophobicContact CE2-CB 4Å; F179-I236 HydrophobicContact CE2-CG2 3.9Å; R232-I236 HydrophobicContact CG-CD1 3.96Å; R232-I236 WeakPolarHBondContact O-CG1 3.33Å; R232-I236 PolarHBondContact O-N 2.87Å; A233-I236 PolarHBondContact O-N 3.5Å; I236-S238 VanDerWaalsContact C-N 3.31Å; I236-S238 PolarHBondContact O-N 3.28Å; I236-A239 WeakPolarHBondContact O-CB 3.45Å; I236-A239 PolarHBondContact O-N 3.42Å; I236-V240 PolarHBondContact O-N 3.27Å
237A98.9Very high98.8Very high2 Ų222.5 Ų22.52%0.01713%0.134CC..Hα-helixtrans-61.5-39.917900000112.2F179 A233 V240 N241 C242 L244F179-A237 HydrophobicContact CD2-CB 3.79Å; F179-A237 HydrophobicContact CE2-CB 3.95Å; A233-A237 WeakPolarHBondContact O-CB 3.38Å; A233-A237 PolarHBondContact O-N 2.97Å; A237-V240 WeakPolarHBondContact O-CG2 3.27Å; A237-V240 PolarHBondContact O-N 3.19Å; A237-N241 PolarHBondContact O-N 3.48Å; A237-C242 PolarHBondContact O-N 3.08Å; A237-L244 HydrophobicContact CB-CB 3.84Å; A237-L244 HydrophobicContact CB-CD1 4.33Å; A237-L244 HydrophobicContact CB-CD2 3.9Å; A237-L244 HydrophobicContact CB-CG 4.26Å
238S98.4Very high98.7Very high42 Ų4222.2 Ų22.229%0.29413%0.13SC..Hα-helixtrans-65.1-38.7176.3-59.70000112I234 T235 I236 V240 N241I234-S238 VanDerWaalsContact O-CB 3.26Å; I234-S238 WeakPolarHBondContact O-CB 3.47Å; I234-S238 PolarHBondContact O-N 2.62Å; I234-S238 PolarHBondContact O-OG 2.86Å; T235-S238 PolarHBondContact O-N 2.73Å; I236-S238 VanDerWaalsContact C-N 3.31Å; I236-S238 PolarHBondContact O-N 3.28Å; S238-V240 PolarHBondContact O-N 3.04Å; S238-N241 PolarHBondContact O-N 3.21Å; S238-N241 VanDerWaalsContact O-N 3.12Å
239A98.4Very high98.7Very high75 Ų7518.9 Ų18.962%0.6212%0.115SC*.Hα-helixtrans-62.5-29.417900000113.2T235 I236T235-A239 PolarHBondContact O-N 2.94Å; I236-A239 WeakPolarHBondContact O-CB 3.45Å; I236-A239 PolarHBondContact O-N 3.42Å
240V98.3Very high98.7Very high17 Ų1719 Ų1910%0.10312%0.115CC..THydrogen-bonded Turntrans-103.44.1176.5-57.60000113Y176 F179 S180 K183 I236 A237 S238 C242Y176-V240 HydrophobicContact CD1-CG1 4.32Å; Y176-V240 HydrophobicContact CD2-CG1 3.53Å; Y176-V240 HydrophobicContact CE1-CG1 4.01Å; Y176-V240 HydrophobicContact CE2-CG1 3.16Å; Y176-V240 HydrophobicContact CG-CG1 4.1Å; Y176-V240 VanDerWaalsContact CZ-CG1 3.42Å; F179-V240 HydrophobicContact CB-CG2 3.66Å; S180-V240 WeakPolarHBondContact OG-CG1 3.2Å; K183-V240 WeakPolarHBondContact CD-O 3.36Å; I236-V240 PolarHBondContact O-N 3.27Å; A237-V240 WeakPolarHBondContact O-CG2 3.27Å; A237-V240 PolarHBondContact O-N 3.19Å; S238-V240 PolarHBondContact O-N 3.04Å; V240-C242 HydrophobicContact CG2-CB 3.66Å; V240-C242 PolarHBondContact O-N 3Å
241N98.5Very high98.7Very high15 Ų1519 Ų198%0.0812%0.115CC..THydrogen-bonded Turntrans53.136.6-174.6-168.531.5000114.1K183 A237 S238 I476 R479 D480K183-N241 HydrophobicContact CD-CB 4.36Å; K183-N241 WeakPolarHBondContact CD-O 3.46Å; K183-N241 WeakPolarHBondContact CE-O 3.36Å; A237-N241 PolarHBondContact O-N 3.48Å; S238-N241 PolarHBondContact O-N 3.21Å; S238-N241 VanDerWaalsContact O-N 3.12Å; N241-I476 PolarHBondContact ND2-O 2.9Å; N241-I476 WeakPolarHBondContact O-CG2 3.45Å; N241-R479 VanDerWaalsContact OD1-CD 3.28Å; N241-R479 WeakPolarHBondContact OD1-CD 3.46Å; N241-R479 PolarHBondContact OD1-NH1 2.84Å; N241-D480 PolarHBondContact ND2-OD1 2.99Å
242C98.8Very high98.7Very high4 Ų416.8 Ų16.83%0.02710%0.102CC..  trans-87.8139.5174.8179.70000110.3F179 K183 A237 V240F179-C242 HydrophobicContact CB-CB 3.9Å; F179-C242 WeakPolarHBondContact O-CB 3.35Å; F179-C242 PolarHBondContact O-SG 3.21Å; K183-C242 HydrophobicContact CB-CB 4.22Å; A237-C242 PolarHBondContact O-N 3.08Å; V240-C242 HydrophobicContact CG2-CB 3.66Å; V240-C242 PolarHBondContact O-N 3Å
243P98.8Very high98.7Very high0 Ų016 Ų160%010%0.103CC..  trans-69.713916926.6-24.8000110.6I188 A189 V267 I472 Y473 I476I188-P243 HydrophobicContact CG1-CB 4.22Å; I188-P243 HydrophobicContact CG1-CG 4.4Å; A189-P243 PolarHBondContact N-O 2.98Å; P243-V267 HydrophobicContact CB-CG1 3.63Å; P243-I472 HydrophobicContact CB-CG2 3.26Å; P243-I472 HydrophobicContact CG-CG2 3.54Å; P243-Y473 HydrophobicContact CG-CE1 4.49Å; P243-Y473 HydrophobicContact CG-CE2 3.96Å; P243-I476 HydrophobicContact CB-CD1 3.8Å; P243-I476 VanDerWaalsContact CD-CD1 3.46Å; P243-I476 HydrophobicContact CG-CD1 3.61Å
244L98.9Very high98.7Very high2 Ų216 Ų161%0.0110%0.103CC..EExtended strand (participates in β ladder)trans-122.9140.7-176.8-173.165.2000111.7F179 A189 V191 A233 I234 A237 I246 V267 V268 Y269F179-L244 HydrophobicContact CE1-CD1 4.3Å; F179-L244 HydrophobicContact CE2-CD1 4.46Å; F179-L244 HydrophobicContact CZ-CD1 4Å; A189-L244 HydrophobicContact CB-CD1 4.16Å; A189-L244 CarbonylContact O-C 3.34Å; A189-L244 WeakPolarHBondContact O-CA 3.36Å; V191-L244 HydrophobicContact CB-CD1 4.34Å; V191-L244 HydrophobicContact CG2-CD1 3.55Å; A233-L244 VanDerWaalsContact C-CD2 3.48Å; A233-L244 HydrophobicContact CB-CD2 3.92Å; I234-L244 HydrophobicContact CB-CD2 4.3Å; I234-L244 HydrophobicContact CG1-CD2 3.72Å; A237-L244 HydrophobicContact CB-CB 3.84Å; A237-L244 HydrophobicContact CB-CD1 4.33Å; A237-L244 HydrophobicContact CB-CD2 3.9Å; A237-L244 HydrophobicContact CB-CG 4.26Å; L244-I246 HydrophobicContact CD2-CD1 3.69Å; L244-I246 HydrophobicContact CG-CD1 3.94Å; L244-V267 PolarHBondContact N-O 2.96Å; L244-V268 HydrophobicContact CB-CG2 4.35Å; L244-V268 HydrophobicContact CD2-CG2 4.44Å; L244-V268 HydrophobicContact CG-CG2 4.48Å; L244-V268 CarbonylContact O-C 3.59Å; L244-V268 VanDerWaalsContact O-CA 3.25Å; L244-V268 WeakPolarHBondContact O-CA 3.34Å; L244-Y269 PolarHBondContact O-N 2.89Å
245Y98.9Very high98.7Very high0 Ų015.9 Ų15.90%010%0.103CC..EExtended strand (participates in β ladder)trans-126.2112.6175.7-172.1-78000108.8T66 I188 A189 Q190 V191 V247 Y269 E271 T322 I385 F386T66-Y245 PolarHBondContact OG1-OH 2.75Å; I188-Y245 HydrophobicContact CD1-CD2 4.17Å; I188-Y245 HydrophobicContact CD1-CG 4.42Å; A189-Y245 PolarHBondContact O-N 2.87Å; Q190-Y245 CarbonylContact C-O 3.44Å; Q190-Y245 WeakPolarHBondContact CA-O 3.48Å; Q190-Y245 HydrophobicContact CG-CD1 4.06Å; Q190-Y245 HydrophobicContact CG-CG 4.29Å; V191-Y245 PolarHBondContact N-O 2.67Å; Y245-V247 HydrophobicContact CD1-CB 4.44Å; Y245-V247 HydrophobicContact CD1-CG1 3.66Å; Y245-V247 HydrophobicContact CE1-CB 4.33Å; Y245-V247 HydrophobicContact CE1-CG1 3.83Å; Y245-V247 PolarHBondContact O-N 2.57Å; Y245-Y269 WeakPolarHBondContact CA-O 3.23Å; Y245-Y269 HydrophobicContact CD2-CG 4.46Å; Y245-E271 HydrophobicContact CE1-CB 3.52Å; Y245-E271 HydrophobicContact CE1-CG 4.13Å; Y245-E271 VanDerWaalsContact CE1-OE2 3.28Å; Y245-E271 WeakPolarHBondContact CE1-OE2 3.43Å; Y245-E271 WeakPolarHBondContact OH-CB 3.3Å; Y245-E271 VanDerWaalsContact OH-CD 3.31Å; Y245-E271 WeakPolarHBondContact OH-CG 3.32Å; Y245-E271 PolarHBondContact OH-OE2 2.81Å; Y245-T322 HydrophobicContact CE2-CG2 4.46Å; Y245-T322 WeakPolarHBondContact CE2-OG1 3.31Å; Y245-T322 PolarHBondContact OH-OG1 3.37Å; Y245-I385 HydrophobicContact CD2-CD1 4.45Å; Y245-I385 HydrophobicContact CD2-CG2 4.08Å; Y245-I385 HydrophobicContact CE2-CD1 4.13Å; Y245-I385 HydrophobicContact CE2-CG2 4.2Å; Y245-F386 HydrophobicContact CD2-CZ 4.33Å; Y245-F386 HydrophobicContact CE2-CE2 4.29Å; Y245-F386 AromaticContact CE2-CZ 3.99Å; Y245-F386 HydrophobicContact CE2-CZ 3.99Å
246I98.9Very high98.7Very high1 Ų117.4 Ų17.41%0.00510%0.103CC..EExtended strand (participates in β ladder)trans-86.1111.1175.1-51.5-61.5000106.9V191 A193 T230 A233 L244 V249 I258 V268 Y269 E271V191-I246 HydrophobicContact CB-CD1 4.47Å; A193-I246 HydrophobicContact CB-CG2 4.25Å; T230-I246 HydrophobicContact CG2-CD1 4.33Å; T230-I246 HydrophobicContact CG2-CG1 4.15Å; T230-I246 HydrophobicContact CG2-CG2 4.39Å; A233-I246 HydrophobicContact CB-CD1 4.36Å; L244-I246 HydrophobicContact CD2-CD1 3.69Å; L244-I246 HydrophobicContact CG-CD1 3.94Å; I246-V249 HydrophobicContact CB-CG2 4.29Å; I246-V249 HydrophobicContact CG2-CG2 3.91Å; I246-I258 HydrophobicContact CB-CD1 3.81Å; I246-I258 HydrophobicContact CB-CG1 4.5Å; I246-I258 HydrophobicContact CG1-CD1 4Å; I246-I258 HydrophobicContact CG1-CG1 4.14Å; I246-I258 HydrophobicContact CG2-CD1 4.05Å; I246-V268 HydrophobicContact CG1-CG2 3.99Å; I246-Y269 PolarHBondContact N-O 2.76Å; I246-E271 PolarHBondContact O-N 3.19Å
247V98.7Very high98.7Very high1 Ų117.9 Ų17.91%0.00611%0.106CC..EExtended strand (participates in β ladder)trans-80.8164.2179.5-430000110.3H67 K159 Q190 V191 Y245 V249 E271H67-V247 VanDerWaalsContact CE1-CG2 3.47Å; H67-V247 WeakPolarHBondContact CE1-CG2 3.38Å; K159-V247 HydrophobicContact CD-CG1 4.46Å; Q190-V247 HydrophobicContact CB-CG1 3.88Å; Q190-V247 HydrophobicContact CG-CG1 4.29Å; V191-V247 PolarHBondContact O-N 3.45Å; Y245-V247 HydrophobicContact CD1-CB 4.44Å; Y245-V247 HydrophobicContact CD1-CG1 3.66Å; Y245-V247 HydrophobicContact CE1-CB 4.33Å; Y245-V247 HydrophobicContact CE1-CG1 3.83Å; Y245-V247 PolarHBondContact O-N 2.57Å; V247-V249 VanDerWaalsContact C-N 3.35Å; V247-V249 PolarHBondContact O-N 2.86Å; V247-E271 WeakPolarHBondContact CB-OE1 3.22Å
248H96.6Very high98.7Very high6 Ų617.8 Ų17.83%0.02811%0.106CC..EExtended strand (participates in β ladder)trans34.361.3174.86035.5000113.7H67 H192 M250 E271 I273 P299 D326H67-H248 AromaticContact CE1-CD2 3.39Å; H67-H248 PolarHBondContact CE1-CD2 3.02Å; H192-H248 AromaticContact CE1-CE1 3.78Å; H192-H248 AromaticContact CE1-NE2 3.8Å; H192-H248 AromaticContact CG-CE1 3.57Å; H192-H248 AromaticContact CG-NE2 3.65Å; H192-H248 AromaticContact ND1-CE1 3.03Å; H192-H248 PolarHBondContact ND1-CE1 3.47Å; H192-H248 AromaticContact ND1-NE2 2.86Å; H192-H248 PolarHBondContact ND1-NE2 3.11Å; H248-M250 HydrophobicContact CB-SD 4.31Å; H248-M250 VanDerWaalsContact O-CG 3.28Å; H248-M250 WeakPolarHBondContact O-CG 3.33Å; H248-M250 PolarHBondContact O-N 2.86Å; H248-E271 CarbonylContact C-O 3.52Å; H248-E271 VanDerWaalsContact CA-O 3.23Å; H248-E271 WeakPolarHBondContact CA-O 3.4Å; H248-E271 PolarHBondContact N-O 2.95Å; H248-E271 PolarHBondContact N-OE1 2.96Å; H248-E271 VanDerWaalsContact N-OE1 3.11Å; H248-I273 HydrophobicContact CB-CD1 4.22Å; H248-I273 HydrophobicContact CB-CG1 4.48Å; H248-I273 HydrophobicContact CB-CG2 3.91Å; H248-P299 WeakPolarHBondContact CE1-CD 3.24Å; H248-P299 WeakPolarHBondContact ND1-CD 3.48Å; H248-D326 IonicContact CD2-OD2 3.14Å
249V98.9Very high98.7Very high0 Ų015.9 Ų15.90%09%0.092CC..EExtended strand (participates in β ladder)trans-69.4114.1174.5-178.80000108.1I246 V247 A254 A255 I258 E271 S276 L311 L320I246-V249 HydrophobicContact CB-CG2 4.29Å; I246-V249 HydrophobicContact CG2-CG2 3.91Å; V247-V249 VanDerWaalsContact C-N 3.35Å; V247-V249 PolarHBondContact O-N 2.86Å; V249-A254 HydrophobicContact CG1-CB 4.35Å; V249-A255 HydrophobicContact CG1-CB 3.89Å; V249-I258 HydrophobicContact CG1-CD1 4.32Å; V249-I258 HydrophobicContact CG2-CD1 3.56Å; V249-E271 PolarHBondContact N-O 3.39Å; V249-S276 PolarHBondContact O-OG 3.32Å; V249-L311 HydrophobicContact CG1-CD2 4.32Å; V249-L320 HydrophobicContact CG1-CD2 4.33Å; V249-L320 HydrophobicContact CG2-CD2 4.34Å
250M98.8Very high98.7Very high1 Ų114.9 Ų14.91%0.0058%0.076CC..  trans-106.8-20.1-172.3-55.5-55.1-8100113.1E226 H248 I273 M297 P299 L301 R302 T307E226-M250 PolarHBondContact OE1-N 3.24Å; H248-M250 HydrophobicContact CB-SD 4.31Å; H248-M250 VanDerWaalsContact O-CG 3.28Å; H248-M250 WeakPolarHBondContact O-CG 3.33Å; H248-M250 PolarHBondContact O-N 2.86Å; M250-I273 HydrophobicContact CE-CD1 3.94Å; M250-I273 HydrophobicContact CE-CG1 4.31Å; M250-I273 HydrophobicContact SD-CD1 3.67Å; M250-I273 HydrophobicContact SD-CG1 3.69Å; M250-M297 HydrophobicContact CE-CG 4.28Å; M250-M297 HydrophobicContact CE-SD 3.67Å; M250-P299 HydrophobicContact CB-CB 4.06Å; M250-P299 HydrophobicContact CG-CB 3.65Å; M250-P299 HydrophobicContact CG-CG 3.85Å; M250-L301 HydrophobicContact CE-CD2 3.75Å; M250-L301 HydrophobicContact CE-CG 4.2Å; M250-R302 VanDerWaalsContact O-CG 3.23Å; M250-R302 WeakPolarHBondContact O-CG 3.31Å; M250-T307 WeakPolarHBondContact O-CG2 3.05Å
251S98.9Very high98.7Very high0 Ų014.2 Ų14.20%07%0.073CC..  trans-121.9156.9-172.961.70000115.5E223 E226 S253 A254 A255E223-S251 VanDerWaalsContact CB-CB 3.45Å; E226-S251 VanDerWaalsContact CD-OG 3.27Å; E226-S251 WeakPolarHBondContact OE2-CB 3.35Å; E226-S251 PolarHBondContact OE2-N 2.9Å; E226-S251 PolarHBondContact OE2-OG 3.47Å; S251-S253 VanDerWaalsContact C-N 3.34Å; S251-A254 VanDerWaalsContact OG-CB 3.27Å; S251-A254 WeakPolarHBondContact OG-CB 3.34Å; S251-A254 PolarHBondContact OG-N 3.21Å; S251-A255 WeakPolarHBondContact O-CB 3.38Å; S251-A255 PolarHBondContact O-N 2.98Å; S251-A255 VanDerWaalsContact O-N 3.08Å
252K98.9Very high98.7Very high42 Ų4216 Ų1618%0.1838%0.079CC..Hα-helixtrans-63-40.9173.4-58-175178.5171.40111.9A255 K256 D304 S306 T307 F310K252-A255 PolarHBondContact O-N 2.84Å; K252-K256 WeakPolarHBondContact O-CB 3.44Å; K252-K256 PolarHBondContact O-N 3.43Å; K252-D304 WeakPolarHBondContact CE-OD2 3.49Å; K252-D304 IonicContact NZ-OD1 3.55Å; K252-D304 IonicContact NZ-OD2 3.78Å; K252-D304 PolarHBondContact NZ-OD2 2.77Å; K252-S306 WeakPolarHBondContact CE-O 3.48Å; K252-S306 PolarHBondContact NZ-OG 3.03Å; K252-T307 HydrophobicContact CG-CG2 4.16Å; K252-F310 HydrophobicContact CB-CD1 3.73Å; K252-F310 HydrophobicContact CB-CE1 3.75Å; K252-F310 HydrophobicContact CB-CG 4.38Å; K252-F310 HydrophobicContact CB-CZ 4.44Å; K252-F310 HydrophobicContact CD-CB 4.14Å; K252-F310 HydrophobicContact CD-CD1 4.16Å; K252-F310 HydrophobicContact CD-CD2 4.41Å; K252-F310 HydrophobicContact CD-CG 3.99Å; K252-F310 HydrophobicContact CG-CB 4.06Å; K252-F310 HydrophobicContact CG-CD1 3.54Å; K252-F310 HydrophobicContact CG-CE1 4.09Å; K252-F310 HydrophobicContact CG-CG 3.84Å
253S98.8Very high98.7Very high28 Ų2823.3 Ų23.320%0.19611%0.106CC..Hα-helixtrans-67.8-44.2-17844.60000112.2E223 S251 K256 V257E223-S253 WeakPolarHBondContact OE1-CB 3.35Å; E223-S253 PolarHBondContact OE1-OG 3.39Å; S251-S253 VanDerWaalsContact C-N 3.34Å; S253-K256 PolarHBondContact O-N 2.98Å; S253-V257 WeakPolarHBondContact O-CG2 3.5Å; S253-V257 PolarHBondContact O-N 2.72Å
254A98.9Very high98.7Very high0 Ų028.7 Ų28.70%013%0.134CC..Hα-helixtrans-63.3-42.8173.100000111.9E226 V249 S251 K256 V257 I258E226-A254 HydrophobicContact CB-CB 4.41Å; E226-A254 HydrophobicContact CG-CB 3.73Å; V249-A254 HydrophobicContact CG1-CB 4.35Å; S251-A254 VanDerWaalsContact OG-CB 3.27Å; S251-A254 WeakPolarHBondContact OG-CB 3.34Å; S251-A254 PolarHBondContact OG-N 3.21Å; A254-K256 VanDerWaalsContact C-N 3.32Å; A254-K256 PolarHBondContact O-N 3.28Å; A254-V257 WeakPolarHBondContact O-CB 3.18Å; A254-V257 PolarHBondContact O-N 3.39Å; A254-I258 WeakPolarHBondContact O-CG1 3.5Å; A254-I258 PolarHBondContact O-N 3.2Å
255A98.9Very high98.6Very high0 Ų030.2 Ų30.20%015%0.151CC..Hα-helixtrans-62.7-37.5176.800000112.6V249 S251 K252 I258 A259 F310 L311 L314 L320V249-A255 HydrophobicContact CG1-CB 3.89Å; S251-A255 WeakPolarHBondContact O-CB 3.38Å; S251-A255 PolarHBondContact O-N 2.98Å; S251-A255 VanDerWaalsContact O-N 3.08Å; K252-A255 PolarHBondContact O-N 2.84Å; A255-I258 PolarHBondContact O-N 2.97Å; A255-A259 WeakPolarHBondContact O-CB 3.24Å; A255-A259 PolarHBondContact O-N 2.8Å; A255-F310 HydrophobicContact CB-CE1 4.48Å; A255-L311 HydrophobicContact CB-CD2 3.53Å; A255-L314 HydrophobicContact CB-CD1 3.5Å; A255-L314 VanDerWaalsContact CB-CD1 3.5Å; A255-L320 HydrophobicContact CB-CD1 4.21Å; A255-L320 HydrophobicContact CB-CD2 4.32Å
256K98.9Very high98.6Very high110 Ų11032.8 Ų32.848%0.47816%0.162SC..Hα-helixtrans-64.3-41.8173.6178.1166.1171.746.30112.2K252 S253 A254 I258 A259 D260K252-K256 WeakPolarHBondContact O-CB 3.44Å; K252-K256 PolarHBondContact O-N 3.43Å; S253-K256 PolarHBondContact O-N 2.98Å; A254-K256 VanDerWaalsContact C-N 3.32Å; A254-K256 PolarHBondContact O-N 3.28Å; K256-I258 VanDerWaalsContact C-N 3.28Å; K256-I258 PolarHBondContact O-N 3.29Å; K256-A259 PolarHBondContact O-N 2.81Å; K256-D260 WeakPolarHBondContact CG-OD2 3.43Å; K256-D260 IonicContact NZ-OD1 3.88Å; K256-D260 IonicContact NZ-OD2 2.7Å; K256-D260 PolarHBondContact NZ-OD2 3.1Å; K256-D260 WeakPolarHBondContact O-CB 3.43Å; K256-D260 VanDerWaalsContact O-CG 3.32Å; K256-D260 PolarHBondContact O-N 2.97Å
257V98.9Very high98.6Very high30 Ų3033 Ų3318%0.18216%0.163CC..Hα-helixtrans-58.9-42.3174.9170.50000110.8A227 T230 L231 I234 S253 A254 A261A227-V257 HydrophobicContact CB-CG2 4.42Å; T230-V257 HydrophobicContact CG2-CB 4.18Å; T230-V257 HydrophobicContact CG2-CG1 3.82Å; L231-V257 HydrophobicContact CB-CG1 3.77Å; L231-V257 HydrophobicContact CD1-CG1 4.17Å; I234-V257 HydrophobicContact CD1-CG1 3.92Å; S253-V257 WeakPolarHBondContact O-CG2 3.5Å; S253-V257 PolarHBondContact O-N 2.72Å; A254-V257 WeakPolarHBondContact O-CB 3.18Å; A254-V257 PolarHBondContact O-N 3.39Å; V257-A261 VanDerWaalsContact O-CB 3.24Å; V257-A261 WeakPolarHBondContact O-CB 3.35Å; V257-A261 PolarHBondContact O-N 3.34Å
258I98.9Very high98.6Very high0 Ų033 Ų330%016%0.164CC..Hα-helixtrans-64.3-48.4176.2-64.9165.3000110.8T230 I234 I246 V249 A254 A255 K256 D260 A261 R262 V268 L320T230-I258 HydrophobicContact CG2-CD1 4.3Å; T230-I258 HydrophobicContact CG2-CG1 3.81Å; I234-I258 HydrophobicContact CD1-CG1 4.34Å; I246-I258 HydrophobicContact CB-CD1 3.81Å; I246-I258 HydrophobicContact CB-CG1 4.5Å; I246-I258 HydrophobicContact CG1-CD1 4Å; I246-I258 HydrophobicContact CG1-CG1 4.14Å; I246-I258 HydrophobicContact CG2-CD1 4.05Å; V249-I258 HydrophobicContact CG1-CD1 4.32Å; V249-I258 HydrophobicContact CG2-CD1 3.56Å; A254-I258 WeakPolarHBondContact O-CG1 3.5Å; A254-I258 PolarHBondContact O-N 3.2Å; A255-I258 PolarHBondContact O-N 2.97Å; K256-I258 VanDerWaalsContact C-N 3.28Å; K256-I258 PolarHBondContact O-N 3.29Å; I258-D260 PolarHBondContact O-N 3.32Å; I258-A261 PolarHBondContact O-N 3.3Å; I258-R262 HydrophobicContact CG2-CG 4.45Å; I258-R262 WeakPolarHBondContact O-CG 3.44Å; I258-R262 PolarHBondContact O-N 3.37Å; I258-V268 HydrophobicContact CG2-CG1 4.32Å; I258-V268 HydrophobicContact CG2-CG2 4.44Å; I258-L320 HydrophobicContact CD1-CD2 4.18Å; I258-L320 HydrophobicContact CG2-CD2 4.47Å
259A98.9Very high98.7Very high2 Ų233 Ų332%0.01716%0.163CC..Hα-helixtrans-57.4-49179.200000111.7A255 K256 A261 R262 R263 D319A255-A259 WeakPolarHBondContact O-CB 3.24Å; A255-A259 PolarHBondContact O-N 2.8Å; K256-A259 PolarHBondContact O-N 2.81Å; A259-A261 PolarHBondContact O-N 3.38Å; A259-R262 PolarHBondContact O-N 3.34Å; A259-R263 WeakPolarHBondContact O-CG 3.34Å; A259-R263 PolarHBondContact O-N 3.26Å; A259-D319 HydrophobicContact CB-CB 3.8Å
260D98.9Very high98.7Very high53 Ų5333 Ų3328%0.28316%0.163SC..Hα-helixtrans-65-40.6-179.9-67.5-21.1000110.8K256 I258 R262 R263 D264K256-D260 WeakPolarHBondContact CG-OD2 3.43Å; K256-D260 IonicContact NZ-OD1 3.88Å; K256-D260 IonicContact NZ-OD2 2.7Å; K256-D260 PolarHBondContact NZ-OD2 3.1Å; K256-D260 WeakPolarHBondContact O-CB 3.43Å; K256-D260 VanDerWaalsContact O-CG 3.32Å; K256-D260 PolarHBondContact O-N 2.97Å; I258-D260 PolarHBondContact O-N 3.32Å; D260-R262 PolarHBondContact O-N 3.05Å; D260-R263 PolarHBondContact O-N 3.34Å; D260-R263 IonicContact OD1-CZ 2.7Å; D260-R263 IonicContact OD1-NH1 2.74Å; D260-R263 PolarHBondContact OD1-NH1 2.95Å; D260-D264 PolarHBondContact O-N 3.03Å
261A98.8Very high98.7Very high4 Ų432.9 Ų32.93%0.03316%0.163CC..Hα-helixtrans-62.3-38.1173.600000113.6I234 V257 I258 A259 D264 G265 K266 V268I234-A261 HydrophobicContact CD1-CB 3.94Å; I234-A261 HydrophobicContact CG2-CB 3.79Å; V257-A261 VanDerWaalsContact O-CB 3.24Å; V257-A261 WeakPolarHBondContact O-CB 3.35Å; V257-A261 PolarHBondContact O-N 3.34Å; I258-A261 PolarHBondContact O-N 3.3Å; A259-A261 PolarHBondContact O-N 3.38Å; A261-D264 WeakPolarHBondContact O-CB 3.46Å; A261-D264 PolarHBondContact O-N 2.8Å; A261-G265 PolarHBondContact O-N 3.06Å; A261-K266 HydrophobicContact CB-CB 4.35Å; A261-K266 HydrophobicContact CB-CD 3.8Å; A261-K266 WeakPolarHBondContact O-CB 3.39Å; A261-K266 WeakPolarHBondContact O-CG 3.27Å; A261-K266 PolarHBondContact O-N 3.07Å; A261-V268 HydrophobicContact CB-CG1 3.88Å
262R98.4Very high98.7Very high52 Ų5232.9 Ų32.920%0.19616%0.163CC..Hα-helixtrans-67.2-39.5175.5-72.1176.464.280.2-7.2111.3I258 A259 D260 D264 G265 V268 D318 D319I258-R262 HydrophobicContact CG2-CG 4.45Å; I258-R262 WeakPolarHBondContact O-CG 3.44Å; I258-R262 PolarHBondContact O-N 3.37Å; A259-R262 PolarHBondContact O-N 3.34Å; D260-R262 PolarHBondContact O-N 3.05Å; R262-D264 VanDerWaalsContact C-N 3.27Å; R262-D264 PolarHBondContact O-N 3.27Å; R262-G265 WeakPolarHBondContact O-CA 3.33Å; R262-G265 PolarHBondContact O-N 2.84Å; R262-V268 HydrophobicContact CG-CG1 3.64Å; R262-V268 PolarHBondContact NH1-O 2.85Å; R262-D318 PolarHBondContact NE-O 3.3Å; R262-D318 PolarHBondContact NH2-O 3.46Å; R262-D318 VanDerWaalsContact NH2-O 3.13Å; R262-D318 IonicContact NH2-OD2 3.68Å; R262-D318 PolarHBondContact NH2-OD2 2.92Å; R262-D319 VanDerWaalsContact CD-O 3.29Å; R262-D319 WeakPolarHBondContact CD-O 3.38Å
263R98.2Very high98.7Very high158 Ų15830.9 Ų30.960%0.59615%0.154SC*.Hα-helixtrans-62.7-33.3173.8-68.6170.5-166.7150.13.6112.3A259 D260 G265 D319A259-R263 WeakPolarHBondContact O-CG 3.34Å; A259-R263 PolarHBondContact O-N 3.26Å; D260-R263 PolarHBondContact O-N 3.34Å; D260-R263 IonicContact OD1-CZ 2.7Å; D260-R263 IonicContact OD1-NH1 2.74Å; D260-R263 PolarHBondContact OD1-NH1 2.95Å; R263-G265 PolarHBondContact O-N 3.15Å; R263-D319 IonicContact NH2-OD1 3.9Å; R263-D319 IonicContact NH2-OD2 3.37Å; R263-D319 PolarHBondContact NH2-OD2 3.44Å
264D98.3Very high98.7Very high112 Ų11229.6 Ų29.660%0.59915%0.145SC*.THydrogen-bonded Turntrans-70.6-2.8170-64.3-19.6000113.6D260 A261 R262 K266D260-D264 PolarHBondContact O-N 3.03Å; A261-D264 WeakPolarHBondContact O-CB 3.46Å; A261-D264 PolarHBondContact O-N 2.8Å; R262-D264 VanDerWaalsContact C-N 3.27Å; R262-D264 PolarHBondContact O-N 3.27Å; D264-K266 HydrophobicContact CB-CD 4.41Å; D264-K266 HydrophobicContact CB-CG 4.26Å; D264-K266 IonicContact OD2-NZ 2.84Å; D264-K266 PolarHBondContact OD2-NZ 3.34Å
265G98Very high98.7Very high35 Ų3529.6 Ų29.636%0.36115%0.145SC..THydrogen-bonded Turntrans80.111.3-177.300000114.6A261 R262 R263 R479A261-G265 PolarHBondContact O-N 3.06Å; R262-G265 WeakPolarHBondContact O-CA 3.33Å; R262-G265 PolarHBondContact O-N 2.84Å; R263-G265 PolarHBondContact O-N 3.15Å; G265-R479 PolarHBondContact O-NH2 2.83Å
266K98.5Very high98.7Very high53 Ų5329.7 Ų29.723%0.2315%0.146CC..  trans-67.2149.3175.9-59.1169.7-178.4140.80110.1I234 A261 D264 V268I234-K266 HydrophobicContact CG2-CD 3.57Å; A261-K266 HydrophobicContact CB-CB 4.35Å; A261-K266 HydrophobicContact CB-CD 3.8Å; A261-K266 WeakPolarHBondContact O-CB 3.39Å; A261-K266 WeakPolarHBondContact O-CG 3.27Å; A261-K266 PolarHBondContact O-N 3.07Å; D264-K266 HydrophobicContact CB-CD 4.41Å; D264-K266 HydrophobicContact CB-CG 4.26Å; D264-K266 IonicContact OD2-NZ 2.84Å; D264-K266 PolarHBondContact OD2-NZ 3.34Å; K266-V268 VanDerWaalsContact C-N 3.31Å; K266-V268 PolarHBondContact O-N 3.37Å; K266-V268 VanDerWaalsContact O-N 3.11Å
267V98.7Very high98.7Very high6 Ų624.6 Ų24.64%0.03612%0.124CC..  trans-89.972.8-177.1-176.90000108.5P243 L244 Y269 I472 R475 I476P243-V267 HydrophobicContact CB-CG1 3.63Å; L244-V267 PolarHBondContact N-O 2.96Å; V267-Y269 HydrophobicContact CG1-CE2 4.26Å; V267-I472 HydrophobicContact CG1-CG2 4.27Å; V267-R475 VanDerWaalsContact CG1-NH2 3.33Å; V267-R475 HydrophobicContact CG2-CG 4.24Å; V267-I476 HydrophobicContact CG1-CD1 4.13Å; V267-I476 HydrophobicContact CG1-CG1 4.31Å; V267-I476 HydrophobicContact CG2-CG1 4.29Å
268V98.9Very high98.7Very high2 Ų223.5 Ų23.51%0.01212%0.119CC..EExtended strand (participates in β ladder)trans-124.6142.5-179.964.40000111.6I234 L244 I246 I258 A261 R262 K266I234-V268 HydrophobicContact CD1-CG1 4.45Å; I234-V268 HydrophobicContact CD1-CG2 4.02Å; I234-V268 HydrophobicContact CG1-CB 4.36Å; I234-V268 HydrophobicContact CG1-CG2 3.87Å; L244-V268 HydrophobicContact CB-CG2 4.35Å; L244-V268 HydrophobicContact CD2-CG2 4.44Å; L244-V268 HydrophobicContact CG-CG2 4.48Å; L244-V268 CarbonylContact O-C 3.59Å; L244-V268 VanDerWaalsContact O-CA 3.25Å; L244-V268 WeakPolarHBondContact O-CA 3.34Å; I246-V268 HydrophobicContact CG1-CG2 3.99Å; I258-V268 HydrophobicContact CG2-CG1 4.32Å; I258-V268 HydrophobicContact CG2-CG2 4.44Å; A261-V268 HydrophobicContact CB-CG1 3.88Å; R262-V268 HydrophobicContact CG-CG1 3.64Å; R262-V268 PolarHBondContact NH1-O 2.85Å; K266-V268 VanDerWaalsContact C-N 3.31Å; K266-V268 PolarHBondContact O-N 3.37Å; K266-V268 VanDerWaalsContact O-N 3.11Å
269Y98.9Very high98.7Very high4 Ų424.2 Ų24.22%0.01612%0.123CC..EExtended strand (participates in β ladder)trans-122.2146.6175.7-58.9-88.3000108.9I188 L244 Y245 I246 V267 T321 I385 Y471 I472 R475I188-Y269 HydrophobicContact CD1-CD2 4Å; I188-Y269 HydrophobicContact CD1-CE2 4.36Å; L244-Y269 PolarHBondContact O-N 2.89Å; Y245-Y269 WeakPolarHBondContact CA-O 3.23Å; Y245-Y269 HydrophobicContact CD2-CG 4.46Å; I246-Y269 PolarHBondContact N-O 2.76Å; V267-Y269 HydrophobicContact CG1-CE2 4.26Å; Y269-T321 HydrophobicContact CD1-CG2 4.02Å; Y269-I385 HydrophobicContact CD1-CD1 3.57Å; Y269-I385 HydrophobicContact CD1-CG1 4.12Å; Y269-I385 HydrophobicContact CE1-CD1 4.04Å; Y269-I385 HydrophobicContact CE1-CG1 4.11Å; Y269-I385 HydrophobicContact CG-CD1 3.99Å; Y269-Y471 AromaticContact CE1-CE1 3.75Å; Y269-Y471 HydrophobicContact CE1-CE1 3.75Å; Y269-I472 HydrophobicContact CE2-CG1 4.08Å; Y269-R475 PolarHBondContact OH-NH2 3.07Å
270G98.9Very high98.7Very high0 Ų025.5 Ų25.50%013%0.13CC..EExtended strand (participates in β ladder)trans-124.9134.5178.700000111T321G270-T321 PolarHBondContact N-OG1 3.23Å; G270-T321 PolarHBondContact O-N 2.88Å; G270-T321 PolarHBondContact O-OG1 3.1Å
271E98.8Very high98.7Very high0 Ų023 Ų230%012%0.116CC..EExtended strand (participates in β ladder)trans-118.194.3179.8177.1-16280.600110.1T66 H67 Y245 I246 V247 H248 V249T66-E271 WeakPolarHBondContact CB-OE2 3.48Å; T66-E271 PolarHBondContact OG1-OE2 2.86Å; H67-E271 IonicContact CE1-OE1 2.69Å; H67-E271 IonicContact CG-OE1 2.93Å; H67-E271 IonicContact ND1-OE1 3.79Å; H67-E271 PolarHBondContact ND1-OE1 3.39Å; Y245-E271 HydrophobicContact CE1-CB 3.52Å; Y245-E271 HydrophobicContact CE1-CG 4.13Å; Y245-E271 VanDerWaalsContact CE1-OE2 3.28Å; Y245-E271 WeakPolarHBondContact CE1-OE2 3.43Å; Y245-E271 WeakPolarHBondContact OH-CB 3.3Å; Y245-E271 VanDerWaalsContact OH-CD 3.31Å; Y245-E271 WeakPolarHBondContact OH-CG 3.32Å; Y245-E271 PolarHBondContact OH-OE2 2.81Å; I246-E271 PolarHBondContact O-N 3.19Å; V247-E271 WeakPolarHBondContact CB-OE1 3.22Å; H248-E271 CarbonylContact C-O 3.52Å; H248-E271 VanDerWaalsContact CA-O 3.23Å; H248-E271 WeakPolarHBondContact CA-O 3.4Å; H248-E271 PolarHBondContact N-O 2.95Å; H248-E271 PolarHBondContact N-OE1 2.96Å; H248-E271 VanDerWaalsContact N-OE1 3.11Å; V249-E271 PolarHBondContact N-O 3.39Å
272P98.9Very high98.7Very high0 Ų025.8 Ų25.80%013%0.133CC..EExtended strand (participates in β ladder)trans-64.3159.9158.530.3-36.8000110.1L277 L315 L320 T322 T323 G324P272-L277 HydrophobicContact CB-CD1 4.09Å; P272-L277 HydrophobicContact CB-CD2 3.94Å; P272-L277 HydrophobicContact CB-CG 3.95Å; P272-L277 HydrophobicContact CG-CD1 4.13Å; P272-L277 HydrophobicContact CG-CD2 4.23Å; P272-L277 HydrophobicContact CG-CG 4.43Å; P272-L315 HydrophobicContact CG-CD1 4.04Å; P272-L315 HydrophobicContact CG-CD2 4.46Å; P272-L320 HydrophobicContact CB-CD1 4.18Å; P272-L320 HydrophobicContact CG-CB 4.14Å; P272-L320 HydrophobicContact CG-CD1 3.82Å; P272-T322 VanDerWaalsContact CD-O 3.27Å; P272-T322 WeakPolarHBondContact CD-O 3.33Å; P272-T323 HydrophobicContact CG-CG2 4.48Å; P272-T323 WeakPolarHBondContact O-CA 3.27Å; P272-G324 PolarHBondContact O-N 2.96Å
273I98.9Very high98.7Very high0 Ų025.6 Ų25.60%013%0.134CC..BIsolated β-bridgetrans-117.5163.2178.956.9167.5000111H248 M250 A275 S276 L277 M297 G324 D326H248-I273 HydrophobicContact CB-CD1 4.22Å; H248-I273 HydrophobicContact CB-CG1 4.48Å; H248-I273 HydrophobicContact CB-CG2 3.91Å; M250-I273 HydrophobicContact CE-CD1 3.94Å; M250-I273 HydrophobicContact CE-CG1 4.31Å; M250-I273 HydrophobicContact SD-CD1 3.67Å; M250-I273 HydrophobicContact SD-CG1 3.69Å; I273-A275 HydrophobicContact CD1-CB 3.91Å; I273-A275 HydrophobicContact CG1-CB 4.19Å; I273-A275 PolarHBondContact O-N 2.72Å; I273-A275 VanDerWaalsContact O-N 3.08Å; I273-S276 PolarHBondContact N-OG 2.93Å; I273-S276 PolarHBondContact O-N 2.95Å; I273-S276 VanDerWaalsContact O-N 3.08Å; I273-S276 PolarHBondContact O-OG 3.16Å; I273-L277 WeakPolarHBondContact O-CG 3.49Å; I273-L277 PolarHBondContact O-N 2.9Å; I273-M297 HydrophobicContact CD1-CE 3.41Å; I273-M297 VanDerWaalsContact CD1-CE 3.41Å; I273-M297 HydrophobicContact CD1-SD 3.94Å; I273-G324 VanDerWaalsContact CA-O 3.22Å; I273-G324 WeakPolarHBondContact CA-O 3.43Å; I273-G324 WeakPolarHBondContact CB-O 3.4Å; I273-D326 HydrophobicContact CD1-CB 3.95Å; I273-D326 HydrophobicContact CG2-CB 4.3Å
274A98.9Very high98.7Very high0 Ų018.1 Ų18.10%011%0.106CC..Hα-helixtrans-47.9-40.7177.300000112.5L277 G278 G324 T325 R355 F428A274-L277 PolarHBondContact O-N 3.48Å; A274-G278 PolarHBondContact O-N 2.7Å; A274-G324 PolarHBondContact N-O 2.97Å; A274-T325 HydrophobicContact CB-CG2 4.02Å; A274-R355 HydrophobicContact CB-CB 4.12Å; A274-R355 HydrophobicContact CB-CG 4.19Å; A274-F428 HydrophobicContact CB-CE2 4.43Å; A274-F428 HydrophobicContact CB-CZ 4.01Å; A274-F428 WeakPolarHBondContact O-CZ 3.3Å
275A98.9Very high98.8Very high1 Ų118.5 Ų18.51%0.00810%0.099CC..Hα-helixtrans-62.2-51.817900000112.2I273 L277 G278 T279 M297 L301 V349 I427I273-A275 HydrophobicContact CD1-CB 3.91Å; I273-A275 HydrophobicContact CG1-CB 4.19Å; I273-A275 PolarHBondContact O-N 2.72Å; I273-A275 VanDerWaalsContact O-N 3.08Å; A275-L277 PolarHBondContact O-N 2.6Å; A275-G278 PolarHBondContact O-N 3.13Å; A275-T279 WeakPolarHBondContact O-CG2 3.39Å; A275-T279 PolarHBondContact O-N 2.83Å; A275-M297 HydrophobicContact CB-SD 4.06Å; A275-L301 HydrophobicContact CB-CD2 3.99Å; A275-L301 WeakPolarHBondContact O-CD2 3.09Å; A275-V349 HydrophobicContact CB-CG2 3.96Å; A275-I427 HydrophobicContact CB-CD1 3.54Å
276S98.9Very high98.8Very high2 Ų219.6 Ų19.61%0.01410%0.097CC..Hα-helixtrans-71.1-16.5-179.364.50000113.9V249 I273 P308V249-S276 PolarHBondContact O-OG 3.32Å; I273-S276 PolarHBondContact N-OG 2.93Å; I273-S276 PolarHBondContact O-N 2.95Å; I273-S276 VanDerWaalsContact O-N 3.08Å; I273-S276 PolarHBondContact O-OG 3.16Å; S276-P308 WeakPolarHBondContact O-CA 3.41Å; S276-P308 WeakPolarHBondContact O-CB 3.42Å
277L98.9Very high98.8Very high2 Ų227.1 Ų27.11%0.0113%0.13CC..Hα-helixtrans-94.5-21.9175.6-65.4171.2000113.6P272 I273 A274 A275 P308 L311 M312 L315 T323 I359P272-L277 HydrophobicContact CB-CD1 4.09Å; P272-L277 HydrophobicContact CB-CD2 3.94Å; P272-L277 HydrophobicContact CB-CG 3.95Å; P272-L277 HydrophobicContact CG-CD1 4.13Å; P272-L277 HydrophobicContact CG-CD2 4.23Å; P272-L277 HydrophobicContact CG-CG 4.43Å; I273-L277 WeakPolarHBondContact O-CG 3.49Å; I273-L277 PolarHBondContact O-N 2.9Å; A274-L277 PolarHBondContact O-N 3.48Å; A275-L277 PolarHBondContact O-N 2.6Å; L277-P308 WeakPolarHBondContact O-CB 3.35Å; L277-L311 HydrophobicContact CD2-CB 3.78Å; L277-M312 HydrophobicContact CB-CE 3.93Å; L277-M312 HydrophobicContact CD1-CE 4.26Å; L277-M312 HydrophobicContact CD2-CB 4.32Å; L277-M312 HydrophobicContact CD2-CE 4Å; L277-M312 HydrophobicContact CD2-SD 4.36Å; L277-M312 HydrophobicContact CG-CE 4.29Å; L277-L315 HydrophobicContact CD1-CD2 3.86Å; L277-L315 HydrophobicContact CD2-CD2 4.47Å; L277-T323 HydrophobicContact CD1-CG2 3.8Å; L277-I359 HydrophobicContact CD1-CG1 4.1Å
278G98.7Very high98.8Very high8 Ų832.1 Ų32.18%0.08215%0.152CC..Hα-helixtrans-106.7-29.5-172.400000114.9A274 A275 M431A274-G278 PolarHBondContact O-N 2.7Å; A275-G278 PolarHBondContact O-N 3.13Å; G278-M431 WeakPolarHBondContact O-CE 3.22Å
279T98.8Very high98.8Very high15 Ų1535.2 Ų35.29%0.09216%0.164CC..  trans-146.3177.2-174.4-168.60000111.7A275 H283 L301 P308 I427 F428A275-T279 WeakPolarHBondContact O-CG2 3.39Å; A275-T279 PolarHBondContact O-N 2.83Å; T279-H283 PolarHBondContact OG1-CD2 2.93Å; T279-H283 PolarHBondContact OG1-NE2 2.94Å; T279-L301 HydrophobicContact CG2-CD1 3.78Å; T279-L301 HydrophobicContact CG2-CD2 4.19Å; T279-P308 WeakPolarHBondContact O-CG 3.45Å; T279-I427 HydrophobicContact CG2-CD1 4.05Å; T279-F428 HydrophobicContact CG2-CD1 4.49Å; T279-F428 HydrophobicContact CG2-CE1 4.14Å
280D98.8Very high98.8Very high29 Ų2938.8 Ų38.816%0.15518%0.18CC..  trans-135.8173.8-174.268.262000113.1T282 H283 P308D280-T282 VanDerWaalsContact C-N 3.3Å; D280-T282 PolarHBondContact O-N 2.94Å; D280-T282 WeakPolarHBondContact OD1-CB 3.31Å; D280-T282 WeakPolarHBondContact OD1-CG2 3.24Å; D280-T282 PolarHBondContact OD1-N 3.32Å; D280-T282 PolarHBondContact OD1-OG1 3.37Å; D280-H283 PolarHBondContact O-CD2 2.74Å; D280-H283 VanDerWaalsContact O-CD2 3.26Å; D280-P308 HydrophobicContact CB-CG 4.29Å
281G98.7Very high98.7Very high0 Ų041 Ų410%019%0.191CC..G310 helixtrans-78.5-4.8-174.100000114.6H283 Y284 W285 L301 R302G281-H283 PolarHBondContact O-N 2.98Å; G281-Y284 WeakPolarHBondContact O-CD2 3.21Å; G281-Y284 PolarHBondContact O-N 3.41Å; G281-W285 VanDerWaalsContact O-CZ3 3.23Å; G281-W285 WeakPolarHBondContact O-CZ3 3.49Å; G281-L301 WeakPolarHBondContact CA-O 3.47Å; G281-R302 PolarHBondContact N-O 3Å
282T98.8Very high98.7Very high63 Ų6341.1 Ų41.139%0.38719%0.191SC..G310 helixtrans-58.3-24.8178.361.40000112D280 Y284 W285 P303 P305D280-T282 VanDerWaalsContact C-N 3.3Å; D280-T282 PolarHBondContact O-N 2.94Å; D280-T282 WeakPolarHBondContact OD1-CB 3.31Å; D280-T282 WeakPolarHBondContact OD1-CG2 3.24Å; D280-T282 PolarHBondContact OD1-N 3.32Å; D280-T282 PolarHBondContact OD1-OG1 3.37Å; T282-Y284 PolarHBondContact O-N 2.76Å; T282-W285 PolarHBondContact O-N 3.2Å; T282-W285 VanDerWaalsContact O-N 3.13Å; T282-P303 WeakPolarHBondContact CG2-O 3.37Å; T282-P305 HydrophobicContact CG2-CG 3.96Å
283H98.7Very high98.7Very high48 Ų4841.1 Ų41.122%0.22219%0.191CC..G310 helixtrans-59.2-24.7174.1-65.9-53.1000114.8T279 D280 G281 W285 N286 H291 A292 H295T279-H283 PolarHBondContact OG1-CD2 2.93Å; T279-H283 PolarHBondContact OG1-NE2 2.94Å; D280-H283 PolarHBondContact O-CD2 2.74Å; D280-H283 VanDerWaalsContact O-CD2 3.26Å; G281-H283 PolarHBondContact O-N 2.98Å; H283-W285 PolarHBondContact O-N 3.43Å; H283-N286 VanDerWaalsContact O-CB 3.32Å; H283-N286 WeakPolarHBondContact O-CB 3.19Å; H283-N286 PolarHBondContact O-N 3.44Å; H283-N286 VanDerWaalsContact O-N 3.12Å; H283-H291 AromaticContact CE1-NE2 3.85Å; H283-H291 AromaticContact CG-NE2 3.49Å; H283-H291 AromaticContact ND1-CE1 3.78Å; H283-H291 AromaticContact ND1-NE2 2.99Å; H283-H291 PolarHBondContact ND1-NE2 2.83Å; H283-A292 VanDerWaalsContact O-CA 3.32Å; H283-A292 WeakPolarHBondContact O-CA 3.32Å; H283-A292 WeakPolarHBondContact O-CB 3.29Å; H283-H295 HydrophobicContact CB-CB 4.24Å; H283-H295 AromaticContact CD2-CD2 3.49Å; H283-H295 PolarHBondContact CD2-CD2 3.16Å; H283-H295 VanDerWaalsContact CD2-CD2 3.49Å; H283-H295 AromaticContact CD2-NE2 3.3Å; H283-H295 PolarHBondContact CD2-NE2 3.4Å; H283-H295 VanDerWaalsContact CD2-NE2 3.3Å; H283-H295 AromaticContact CG-CD2 3.77Å; H283-H295 AromaticContact CG-CE1 3.78Å; H283-H295 AromaticContact CG-NE2 3.53Å; H283-H295 AromaticContact NE2-NE2 3.89Å
284Y98.8Very high98.7Very high0 Ų042 Ų420%020%0.196CC..G310 helixtrans-65.4-22176.1-60.9-52.1000113.5P214 E218 G281 T282 H295 V296 P300 L301P214-Y284 HydrophobicContact CB-CD1 4.42Å; E218-Y284 HydrophobicContact CB-CD2 3.8Å; E218-Y284 HydrophobicContact CB-CE2 4.15Å; E218-Y284 HydrophobicContact CG-CD2 4.13Å; E218-Y284 HydrophobicContact CG-CE2 4.31Å; G281-Y284 WeakPolarHBondContact O-CD2 3.21Å; G281-Y284 PolarHBondContact O-N 3.41Å; T282-Y284 PolarHBondContact O-N 2.76Å; Y284-H295 HydrophobicContact CD1-CB 4.2Å; Y284-H295 VanDerWaalsContact CE1-C 3.42Å; Y284-H295 HydrophobicContact CE1-CB 3.71Å; Y284-H295 WeakPolarHBondContact CE1-O 3.3Å; Y284-H295 PolarHBondContact OH-O 3.29Å; Y284-V296 HydrophobicContact CD1-CG2 4.27Å; Y284-V296 HydrophobicContact CE1-CG2 4Å; Y284-P300 HydrophobicContact CE2-CB 3.9Å; Y284-L301 HydrophobicContact CE2-CB 4.06Å; Y284-L301 VanDerWaalsContact CE2-O 3.3Å; Y284-L301 WeakPolarHBondContact CE2-O 3.45Å; Y284-L301 PolarHBondContact OH-N 3.25Å
285W98.8Very high98.7Very high121 Ų12142.2 Ų42.246%0.45820%0.197SC..G310 helixtrans-95.812.8176.8-70.3-95000112.9E215 E218 L219 G281 T282 H283 K287 P303E215-W285 HydrophobicContact CB-CD2 4.25Å; E215-W285 HydrophobicContact CB-CG 4.43Å; E215-W285 HydrophobicContact CB-CZ2 4.28Å; E218-W285 HydrophobicContact CB-CH2 4.04Å; E218-W285 HydrophobicContact CG-CH2 3.97Å; E218-W285 HydrophobicContact CG-CZ3 4.4Å; E218-W285 WeakPolarHBondContact OE2-CH2 3.46Å; L219-W285 HydrophobicContact CD2-CZ2 4.23Å; L219-W285 HydrophobicContact CG-CZ2 4.31Å; G281-W285 VanDerWaalsContact O-CZ3 3.23Å; G281-W285 WeakPolarHBondContact O-CZ3 3.49Å; T282-W285 PolarHBondContact O-N 3.2Å; T282-W285 VanDerWaalsContact O-N 3.13Å; H283-W285 PolarHBondContact O-N 3.43Å; W285-K287 PolarHBondContact O-N 3.04Å; W285-P303 HydrophobicContact CH2-CB 3.96Å; W285-P303 HydrophobicContact CH2-CG 4.19Å; W285-P303 HydrophobicContact CZ3-CB 3.69Å; W285-P303 HydrophobicContact CZ3-CG 4.36Å
286N98.7Very high98.7Very high57 Ų5742.2 Ų42.231%0.30520%0.196SC..  trans-63.3136.8173.5-167-40.1000110H283 E288 H291 A292H283-N286 VanDerWaalsContact O-CB 3.32Å; H283-N286 WeakPolarHBondContact O-CB 3.19Å; H283-N286 PolarHBondContact O-N 3.44Å; H283-N286 VanDerWaalsContact O-N 3.12Å; N286-E288 PolarHBondContact O-N 2.86Å; N286-E288 PolarHBondContact OD1-N 3.32Å; N286-H291 HydrophobicContact CB-CB 4.27Å; N286-H291 VanDerWaalsContact CB-CD2 3.46Å; N286-H291 WeakPolarHBondContact CB-CD2 3.45Å; N286-H291 PolarHBondContact ND2-CD2 3.01Å; N286-A292 HydrophobicContact CB-CB 4.36Å
287K98.4Very high98.7Very high212 Ų21242.1 Ų42.192%0.92220%0.196SC*.SBendtrans-63.1-28.3177.1-64.7-176178.9179.30112.5W285 W289W285-K287 PolarHBondContact O-N 3.04Å; K287-W289 PolarHBondContact O-N 3.49Å
288E98.4Very high98.6Very high110 Ų11042.1 Ų42.151%0.51420%0.196SC..SBendtrans-81.4106.8173.1-65.2-166.3109.900109.8N286 H290 H291 A292N286-E288 PolarHBondContact O-N 2.86Å; N286-E288 PolarHBondContact OD1-N 3.32Å; E288-H290 PolarHBondContact O-N 2.79Å; E288-H290 VanDerWaalsContact O-N 3.16Å; E288-H290 IonicContact OE1-CE1 2.67Å; E288-H291 HydrophobicContact CB-CB 4.13Å; E288-H291 WeakPolarHBondContact O-CB 3.47Å; E288-H291 PolarHBondContact O-N 3.11Å; E288-H291 VanDerWaalsContact O-N 3.11Å; E288-A292 PolarHBondContact O-N 3.4Å; E288-A292 VanDerWaalsContact O-N 3.15Å
289W98.7Very high98.6Very high68 Ų6841.8 Ų41.826%0.25819%0.193SC..Hα-helixtrans-52.7-41.4-176.4179.592.7000113.1K287 A292 A293 K335 A336 K339 I345K287-W289 PolarHBondContact O-N 3.49Å; W289-A292 PolarHBondContact O-N 3.16Å; W289-A293 HydrophobicContact CD2-CB 4.31Å; W289-A293 HydrophobicContact CE3-CB 4.16Å; W289-A293 HydrophobicContact CH2-CB 3.44Å; W289-A293 VanDerWaalsContact CH2-CB 3.44Å; W289-A293 HydrophobicContact CZ2-CB 3.67Å; W289-A293 HydrophobicContact CZ3-CB 3.74Å; W289-A293 WeakPolarHBondContact O-CB 3.07Å; W289-A293 PolarHBondContact O-N 3.07Å; W289-K335 HydrophobicContact CH2-CB 4.48Å; W289-K335 WeakPolarHBondContact CH2-O 3.43Å; W289-A336 VanDerWaalsContact CH2-CA 3.49Å; W289-A336 HydrophobicContact CH2-CB 4.33Å; W289-A336 HydrophobicContact CZ3-CB 4.17Å; W289-K339 HydrophobicContact CH2-CB 4.27Å; W289-K339 HydrophobicContact CZ2-CB 4Å; W289-K339 PolarHBondContact NE1-O 2.96Å; W289-I345 HydrophobicContact CZ2-CD1 3.9Å; W289-I345 HydrophobicContact CZ2-CG1 4.23Å
290H98.3Very high98.6Very high78 Ų7841.1 Ų41.136%0.36119%0.188SC..Hα-helixtrans-65.7-42.2-178.159.4-88.5000111.6E288 A292 A293 H294 T332E288-H290 PolarHBondContact O-N 2.79Å; E288-H290 VanDerWaalsContact O-N 3.16Å; E288-H290 IonicContact OE1-CE1 2.67Å; H290-A292 VanDerWaalsContact C-N 3.34Å; H290-A292 PolarHBondContact O-N 3.05Å; H290-A293 PolarHBondContact O-N 3.49Å; H290-H294 PolarHBondContact O-CD2 2.91Å; H290-H294 PolarHBondContact O-N 3.39Å; H290-H294 PolarHBondContact O-ND1 3.4Å; H290-H294 PolarHBondContact O-NE2 3.24Å; H290-T332 HydrophobicContact CB-CG2 3.9Å
291H98.7Very high98.6Very high48 Ų4839.8 Ų39.822%0.22218%0.181CC..Hα-helixtrans-57.3-48.1173.2179.2101.2000111.1H283 N286 E288 A293 H294 H295H283-H291 AromaticContact CE1-NE2 3.85Å; H283-H291 AromaticContact CG-NE2 3.49Å; H283-H291 AromaticContact ND1-CE1 3.78Å; H283-H291 AromaticContact ND1-NE2 2.99Å; H283-H291 PolarHBondContact ND1-NE2 2.83Å; N286-H291 HydrophobicContact CB-CB 4.27Å; N286-H291 VanDerWaalsContact CB-CD2 3.46Å; N286-H291 WeakPolarHBondContact CB-CD2 3.45Å; N286-H291 PolarHBondContact ND2-CD2 3.01Å; E288-H291 HydrophobicContact CB-CB 4.13Å; E288-H291 WeakPolarHBondContact O-CB 3.47Å; E288-H291 PolarHBondContact O-N 3.11Å; E288-H291 VanDerWaalsContact O-N 3.11Å; H291-A293 VanDerWaalsContact C-N 3.35Å; H291-A293 PolarHBondContact O-N 3.01Å; H291-H294 WeakPolarHBondContact O-CB 3.28Å; H291-H294 PolarHBondContact O-N 3.5Å; H291-H295 AromaticContact CD2-CE1 3.93Å; H291-H295 AromaticContact CD2-ND1 4Å; H291-H295 AromaticContact CE1-CE1 3.75Å; H291-H295 AromaticContact NE2-CE1 3.39Å; H291-H295 PolarHBondContact NE2-CE1 3.3Å; H291-H295 AromaticContact NE2-ND1 3.87Å; H291-H295 PolarHBondContact O-ND1 2.73Å
292A98.8Very high98.6Very high1 Ų140 Ų401%0.00818%0.182CC..Hα-helixtrans-62.9-41.9179.100000111.8P214 H283 N286 E288 W289 H290 H294 H295P214-A292 HydrophobicContact CB-CB 3.86Å; P214-A292 HydrophobicContact CG-CB 3.75Å; H283-A292 VanDerWaalsContact O-CA 3.32Å; H283-A292 WeakPolarHBondContact O-CA 3.32Å; H283-A292 WeakPolarHBondContact O-CB 3.29Å; N286-A292 HydrophobicContact CB-CB 4.36Å; E288-A292 PolarHBondContact O-N 3.4Å; E288-A292 VanDerWaalsContact O-N 3.15Å; W289-A292 PolarHBondContact O-N 3.16Å; H290-A292 VanDerWaalsContact C-N 3.34Å; H290-A292 PolarHBondContact O-N 3.05Å; A292-H294 VanDerWaalsContact C-N 3.34Å; A292-H294 PolarHBondContact O-N 2.85Å; A292-H295 PolarHBondContact O-N 2.78Å
293A98.8Very high98.6Very high0 Ų039 Ų390%018%0.177CC..Hα-helixtrans-68-29.4178.400000113.6P214 W289 H290 H291 H295 V296 K335 I345P214-A293 HydrophobicContact CG-CB 4.08Å; W289-A293 HydrophobicContact CD2-CB 4.31Å; W289-A293 HydrophobicContact CE3-CB 4.16Å; W289-A293 HydrophobicContact CH2-CB 3.44Å; W289-A293 VanDerWaalsContact CH2-CB 3.44Å; W289-A293 HydrophobicContact CZ2-CB 3.67Å; W289-A293 HydrophobicContact CZ3-CB 3.74Å; W289-A293 WeakPolarHBondContact O-CB 3.07Å; W289-A293 PolarHBondContact O-N 3.07Å; H290-A293 PolarHBondContact O-N 3.49Å; H291-A293 VanDerWaalsContact C-N 3.35Å; H291-A293 PolarHBondContact O-N 3.01Å; A293-H295 PolarHBondContact O-N 3.39Å; A293-V296 WeakPolarHBondContact O-CB 3.34Å; A293-V296 PolarHBondContact O-N 3.01Å; A293-K335 HydrophobicContact CB-CB 4.3Å; A293-K335 WeakPolarHBondContact O-CD 3.34Å; A293-K335 WeakPolarHBondContact O-CE 3.33Å; A293-I345 HydrophobicContact CB-CD1 4.24Å
294H98.8Very high98.6Very high20 Ų2039.8 Ų39.89%0.09318%0.183CC..Hα-helixtrans-58.9-28.1175.4-67.3166.6000113H290 H291 A292 T332 F425H290-H294 PolarHBondContact O-CD2 2.91Å; H290-H294 PolarHBondContact O-N 3.39Å; H290-H294 PolarHBondContact O-ND1 3.4Å; H290-H294 PolarHBondContact O-NE2 3.24Å; H291-H294 WeakPolarHBondContact O-CB 3.28Å; H291-H294 PolarHBondContact O-N 3.5Å; A292-H294 VanDerWaalsContact C-N 3.34Å; A292-H294 PolarHBondContact O-N 2.85Å; H294-T332 PolarHBondContact NE2-OG1 2.94Å; H294-F425 HydrophobicContact CB-CD1 4.35Å; H294-F425 HydrophobicContact CB-CD2 3.64Å; H294-F425 HydrophobicContact CB-CE1 4.24Å; H294-F425 HydrophobicContact CB-CE2 3.56Å; H294-F425 HydrophobicContact CB-CG 4.06Å; H294-F425 HydrophobicContact CB-CZ 3.88Å; H294-F425 AromaticContact CD2-CD1 3.28Å; H294-F425 WeakPolarHBondContact CD2-CD1 3.17Å; H294-F425 AromaticContact CD2-CE1 3.34Å; H294-F425 WeakPolarHBondContact CD2-CE1 3.13Å; H294-F425 AromaticContact CD2-CG 3.7Å; H294-F425 AromaticContact CD2-CZ 3.87Å; H294-F425 AromaticContact CE1-CD1 3.76Å; H294-F425 AromaticContact CE1-CG 3.72Å; H294-F425 AromaticContact CG-CD1 3.64Å; H294-F425 AromaticContact CG-CD2 3.67Å; H294-F425 AromaticContact CG-CE1 3.84Å; H294-F425 AromaticContact CG-CE2 3.92Å; H294-F425 AromaticContact CG-CG 3.53Å; H294-F425 AromaticContact ND1-CD1 3.94Å; H294-F425 AromaticContact ND1-CD2 3.95Å; H294-F425 AromaticContact ND1-CG 3.57Å; H294-F425 AromaticContact NE2-CD1 3.37Å; H294-F425 WeakPolarHBondContact NE2-CD1 3.11Å; H294-F425 AromaticContact NE2-CE1 3.88Å; H294-F425 AromaticContact NE2-CG 3.81Å; H294-F425 WeakPolarHBondContact O-CE2 3.26Å
295H98.8Very high98.6Very high4 Ų443.8 Ų43.82%0.01921%0.208CC..THydrogen-bonded Turntrans-90.8-3.7-177.6-66.278.2000113.3H283 Y284 H291 A292 A293 M297 L301H283-H295 HydrophobicContact CB-CB 4.24Å; H283-H295 AromaticContact CD2-CD2 3.49Å; H283-H295 PolarHBondContact CD2-CD2 3.16Å; H283-H295 VanDerWaalsContact CD2-CD2 3.49Å; H283-H295 AromaticContact CD2-NE2 3.3Å; H283-H295 PolarHBondContact CD2-NE2 3.4Å; H283-H295 VanDerWaalsContact CD2-NE2 3.3Å; H283-H295 AromaticContact CG-CD2 3.77Å; H283-H295 AromaticContact CG-CE1 3.78Å; H283-H295 AromaticContact CG-NE2 3.53Å; H283-H295 AromaticContact NE2-NE2 3.89Å; Y284-H295 HydrophobicContact CD1-CB 4.2Å; Y284-H295 VanDerWaalsContact CE1-C 3.42Å; Y284-H295 HydrophobicContact CE1-CB 3.71Å; Y284-H295 WeakPolarHBondContact CE1-O 3.3Å; Y284-H295 PolarHBondContact OH-O 3.29Å; H291-H295 AromaticContact CD2-CE1 3.93Å; H291-H295 AromaticContact CD2-ND1 4Å; H291-H295 AromaticContact CE1-CE1 3.75Å; H291-H295 AromaticContact NE2-CE1 3.39Å; H291-H295 PolarHBondContact NE2-CE1 3.3Å; H291-H295 AromaticContact NE2-ND1 3.87Å; H291-H295 PolarHBondContact O-ND1 2.73Å; A292-H295 PolarHBondContact O-N 2.78Å; A293-H295 PolarHBondContact O-N 3.39Å; H295-M297 PolarHBondContact O-N 2.89Å; H295-L301 HydrophobicContact CB-CD1 4.19Å
296V98.8Very high98.6Very high0 Ų040.7 Ų40.70%021%0.206CC..  trans-71.8115.8-174.6172.30000111P214 H217 Y284 A293 K335 I345 N347 G348P214-V296 HydrophobicContact CB-CG2 3.82Å; H217-V296 HydrophobicContact CB-CG1 4.49Å; Y284-V296 HydrophobicContact CD1-CG2 4.27Å; Y284-V296 HydrophobicContact CE1-CG2 4Å; A293-V296 WeakPolarHBondContact O-CB 3.34Å; A293-V296 PolarHBondContact O-N 3.01Å; V296-K335 PolarHBondContact O-NZ 2.86Å; V296-I345 HydrophobicContact CB-CG2 3.88Å; V296-I345 HydrophobicContact CG1-CB 4.11Å; V296-I345 HydrophobicContact CG1-CG2 3.83Å; V296-I345 HydrophobicContact CG2-CD1 4.14Å; V296-I345 HydrophobicContact CG2-CG2 4.27Å; V296-N347 WeakPolarHBondContact CG1-OD1 3.28Å; V296-G348 PolarHBondContact O-N 2.95Å
297M98.7Very high98.6Very high1 Ų138.1 Ų38.11%0.00519%0.192CC..  trans-150.5167.6172.469.5-176.5-45.600111.5H217 M250 I273 A275 H295 P299 P300 D326 V349H217-M297 PolarHBondContact CD2-O 3.04Å; H217-M297 PolarHBondContact NE2-O 3.16Å; M250-M297 HydrophobicContact CE-CG 4.28Å; M250-M297 HydrophobicContact CE-SD 3.67Å; I273-M297 HydrophobicContact CD1-CE 3.41Å; I273-M297 VanDerWaalsContact CD1-CE 3.41Å; I273-M297 HydrophobicContact CD1-SD 3.94Å; A275-M297 HydrophobicContact CB-SD 4.06Å; H295-M297 PolarHBondContact O-N 2.89Å; M297-P299 CarbonylContact C-O 3.05Å; M297-P299 WeakPolarHBondContact CG-O 3.39Å; M297-P299 CarbonylContact O-C 3.41Å; M297-P300 VanDerWaalsContact O-CA 3.31Å; M297-P300 WeakPolarHBondContact O-CA 3.36Å; M297-D326 HydrophobicContact CE-CB 3.96Å; M297-D326 WeakPolarHBondContact CE-OD2 3.38Å; M297-V349 HydrophobicContact CB-CG1 4.19Å; M297-V349 HydrophobicContact CE-CG2 3.68Å; M297-V349 HydrophobicContact CG-CG1 4.33Å; M297-V349 HydrophobicContact SD-CB 4.38Å; M297-V349 HydrophobicContact SD-CG1 3.96Å; M297-V349 HydrophobicContact SD-CG2 3.51Å; M297-V349 VanDerWaalsContact SD-CG2 3.51Å
298G97.1Very high98.6Very high2 Ų228.7 Ų28.72%0.02115%0.152CC..SBendtrans-123.1123.8-178.900000112.1H192H192-G298 PolarHBondContact CE1-O 3.2Å; H192-G298 VanDerWaalsContact CE1-O 3.3Å
299P98.5Very high98.6Very high1 Ų127.3 Ų27.31%0.00615%0.149CC..SBendcis-62.6158.3-6.2-1223.7000112E194 E226 H248 M250 M297E194-P299 VanDerWaalsContact CD-CB 3.49Å; E194-P299 HydrophobicContact CG-CB 3.99Å; E194-P299 HydrophobicContact CG-CG 3.71Å; E194-P299 WeakPolarHBondContact OE1-CB 3.33Å; E194-P299 WeakPolarHBondContact OE2-CA 3.43Å; E226-P299 HydrophobicContact CG-CG 4.28Å; H248-P299 WeakPolarHBondContact CE1-CD 3.24Å; H248-P299 WeakPolarHBondContact ND1-CD 3.48Å; M250-P299 HydrophobicContact CB-CB 4.06Å; M250-P299 HydrophobicContact CG-CB 3.65Å; M250-P299 HydrophobicContact CG-CG 3.85Å; M297-P299 CarbonylContact C-O 3.05Å; M297-P299 WeakPolarHBondContact CG-O 3.39Å; M297-P299 CarbonylContact O-C 3.41Å
300P98.6Very high98.6Very high0 Ų027.3 Ų27.30%015%0.15CC..PPolyproline II helixtrans-76.1156.2-176.833.6-33.8000110.7E218 R221 Y284 M297 R302E218-P300 HydrophobicContact CB-CB 4.41Å; E218-P300 HydrophobicContact CG-CB 4.38Å; E218-P300 HydrophobicContact CG-CG 4.28Å; R221-P300 HydrophobicContact CG-CG 3.65Å; Y284-P300 HydrophobicContact CE2-CB 3.9Å; M297-P300 VanDerWaalsContact O-CA 3.31Å; M297-P300 WeakPolarHBondContact O-CA 3.36Å; P300-R302 PolarHBondContact O-NE 3.26Å
301L98.9Very high98.7Very high1 Ų123.6 Ų23.61%0.00513%0.133CC..PPolyproline II helixtrans-57.6140.1164.5-68.4165.7000109.3M250 A275 T279 G281 Y284 H295M250-L301 HydrophobicContact CE-CD2 3.75Å; M250-L301 HydrophobicContact CE-CG 4.2Å; A275-L301 HydrophobicContact CB-CD2 3.99Å; A275-L301 WeakPolarHBondContact O-CD2 3.09Å; T279-L301 HydrophobicContact CG2-CD1 3.78Å; T279-L301 HydrophobicContact CG2-CD2 4.19Å; G281-L301 WeakPolarHBondContact CA-O 3.47Å; Y284-L301 HydrophobicContact CE2-CB 4.06Å; Y284-L301 VanDerWaalsContact CE2-O 3.3Å; Y284-L301 WeakPolarHBondContact CE2-O 3.45Å; Y284-L301 PolarHBondContact OH-N 3.25Å; H295-L301 HydrophobicContact CB-CD1 4.19Å
302R98.8Very high98.7Very high4 Ų421.3 Ų21.32%0.01512%0.123CC..PPolyproline II helixtrans-87.2135.9-175.2-57.1-54.1177.7-179.6-2.6111.1R221 E226 M250 G281 P300 D304 T307R221-R302 PolarHBondContact O-NH1 3.48Å; E226-R302 IonicContact OE2-CZ 2.79Å; E226-R302 IonicContact OE2-NE 2.77Å; E226-R302 IonicContact OE2-NH2 3.85Å; E226-R302 PolarHBondContact OE2-NH2 2.81Å; M250-R302 VanDerWaalsContact O-CG 3.23Å; M250-R302 WeakPolarHBondContact O-CG 3.31Å; G281-R302 PolarHBondContact N-O 3Å; P300-R302 PolarHBondContact O-NE 3.26Å; R302-D304 PolarHBondContact O-N 3.37Å; R302-T307 HydrophobicContact CB-CG2 4.1Å; R302-T307 HydrophobicContact CG-CG2 4.26Å
303P98.5Very high98.7Very high44 Ų4424.2 Ų24.229%0.28614%0.138SC..SBendtrans-70.1-12.8-176.227.3-34.3000113.8E218 T282 W285 P305E218-P303 HydrophobicContact CG-CG 4.4Å; E218-P303 VanDerWaalsContact OE1-CD 3.32Å; E218-P303 WeakPolarHBondContact OE1-CD 3.49Å; T282-P303 WeakPolarHBondContact CG2-O 3.37Å; W285-P303 HydrophobicContact CH2-CB 3.96Å; W285-P303 HydrophobicContact CH2-CG 4.19Å; W285-P303 HydrophobicContact CZ3-CB 3.69Å; W285-P303 HydrophobicContact CZ3-CG 4.36Å; P303-P305 WeakPolarHBondContact O-CD 3.43Å
304D98.7Very high98.7Very high64 Ų6424.9 Ų24.934%0.34214%0.142SC..  trans-71.6110.3170.2178.2-9.7000109.6K252 R302 S306 T307K252-D304 WeakPolarHBondContact CE-OD2 3.49Å; K252-D304 IonicContact NZ-OD1 3.55Å; K252-D304 IonicContact NZ-OD2 3.78Å; K252-D304 PolarHBondContact NZ-OD2 2.77Å; R302-D304 PolarHBondContact O-N 3.37Å; D304-S306 PolarHBondContact O-N 2.95Å; D304-S306 WeakPolarHBondContact OD1-CB 3.33Å; D304-S306 PolarHBondContact OD1-N 2.81Å; D304-S306 PolarHBondContact OD1-OG 2.92Å; D304-S306 PolarHBondContact OD2-OG 2.79Å; D304-T307 VanDerWaalsContact O-CB 3.28Å; D304-T307 WeakPolarHBondContact O-CB 3.44Å; D304-T307 PolarHBondContact O-N 2.94Å; D304-T307 PolarHBondContact O-OG1 2.83Å
305P98.6Very high98.7Very high83 Ų8324 Ų2454%0.53914%0.137SC..THydrogen-bonded Turntrans-66.6-11.6-175.1-19.934.7000114T282 P303 T307 P308T282-P305 HydrophobicContact CG2-CG 3.96Å; P303-P305 WeakPolarHBondContact O-CD 3.43Å; P305-T307 VanDerWaalsContact C-N 3.33Å; P305-P308 WeakPolarHBondContact O-CD 3.29Å
306S98.8Very high98.7Very high57 Ų5724.9 Ų24.940%0.39915%0.146SC..THydrogen-bonded Turntrans-89.41.6174.864.80000113.2K252 D304 F310K252-S306 WeakPolarHBondContact CE-O 3.48Å; K252-S306 PolarHBondContact NZ-OG 3.03Å; D304-S306 PolarHBondContact O-N 2.95Å; D304-S306 WeakPolarHBondContact OD1-CB 3.33Å; D304-S306 PolarHBondContact OD1-N 2.81Å; D304-S306 PolarHBondContact OD1-OG 2.92Å; D304-S306 PolarHBondContact OD2-OG 2.79Å; S306-F310 WeakPolarHBondContact O-CB 3.47Å; S306-F310 PolarHBondContact O-N 2.89Å; S306-F310 VanDerWaalsContact O-N 3.11Å
307T98.9Very high98.7Very high3 Ų329 Ų292%0.01817%0.167CC..Hα-helixtrans-61.1-49.1175-56.60000112.7M250 K252 R302 D304 P305 D309 F310 L311M250-T307 WeakPolarHBondContact O-CG2 3.05Å; K252-T307 HydrophobicContact CG-CG2 4.16Å; R302-T307 HydrophobicContact CB-CG2 4.1Å; R302-T307 HydrophobicContact CG-CG2 4.26Å; D304-T307 VanDerWaalsContact O-CB 3.28Å; D304-T307 WeakPolarHBondContact O-CB 3.44Å; D304-T307 PolarHBondContact O-N 2.94Å; D304-T307 PolarHBondContact O-OG1 2.83Å; P305-T307 VanDerWaalsContact C-N 3.33Å; T307-D309 VanDerWaalsContact C-N 3.34Å; T307-D309 PolarHBondContact O-N 3.41Å; T307-F310 PolarHBondContact O-N 3.06Å; T307-L311 HydrophobicContact CG2-CD1 3.93Å; T307-L311 HydrophobicContact CG2-CG 4.14Å; T307-L311 WeakPolarHBondContact O-CG 3.48Å; T307-L311 PolarHBondContact O-N 3.3Å
308P98.9Very high98.7Very high14 Ų1431 Ų319%0.09118%0.178CC..Hα-helixtrans-61.3-41.7-179-25.738000113.2S276 L277 T279 D280 P305 F310 L311 M312S276-P308 WeakPolarHBondContact O-CA 3.41Å; S276-P308 WeakPolarHBondContact O-CB 3.42Å; L277-P308 WeakPolarHBondContact O-CB 3.35Å; T279-P308 WeakPolarHBondContact O-CG 3.45Å; D280-P308 HydrophobicContact CB-CG 4.29Å; P305-P308 WeakPolarHBondContact O-CD 3.29Å; P308-F310 PolarHBondContact O-N 3.21Å; P308-L311 PolarHBondContact O-N 2.86Å; P308-M312 WeakPolarHBondContact O-CB 3.2Å; P308-M312 PolarHBondContact O-N 2.88Å
309D98.8Very high98.8Very high81 Ų8131.6 Ų31.643%0.43318%0.181SC..Hα-helixtrans-60.7-45.2176-169.285.1000111.9T307 M312 N313 K368T307-D309 VanDerWaalsContact C-N 3.34Å; T307-D309 PolarHBondContact O-N 3.41Å; D309-M312 PolarHBondContact O-N 3.05Å; D309-N313 VanDerWaalsContact O-CG 3.24Å; D309-N313 PolarHBondContact O-N 3.06Å; D309-N313 PolarHBondContact O-ND2 2.86Å; D309-N313 VanDerWaalsContact O-ND2 3.12Å; D309-N313 PolarHBondContact OD2-ND2 2.97Å; D309-N313 VanDerWaalsContact OD2-ND2 3.12Å; D309-K368 WeakPolarHBondContact OD1-CE 3.5Å; D309-K368 IonicContact OD1-NZ 3.46Å; D309-K368 PolarHBondContact OD1-NZ 2.67Å; D309-K368 IonicContact OD2-NZ 3.37Å; D309-K368 PolarHBondContact OD2-NZ 3.4Å
310F98.9Very high98.8Very high67 Ų6731.6 Ų31.629%0.29418%0.181SC..Hα-helixtrans-63.2-46.9178.4-177.6-91.1000112K252 A255 S306 T307 P308 M312 N313 L314K252-F310 HydrophobicContact CB-CD1 3.73Å; K252-F310 HydrophobicContact CB-CE1 3.75Å; K252-F310 HydrophobicContact CB-CG 4.38Å; K252-F310 HydrophobicContact CB-CZ 4.44Å; K252-F310 HydrophobicContact CD-CB 4.14Å; K252-F310 HydrophobicContact CD-CD1 4.16Å; K252-F310 HydrophobicContact CD-CD2 4.41Å; K252-F310 HydrophobicContact CD-CG 3.99Å; K252-F310 HydrophobicContact CG-CB 4.06Å; K252-F310 HydrophobicContact CG-CD1 3.54Å; K252-F310 HydrophobicContact CG-CE1 4.09Å; K252-F310 HydrophobicContact CG-CG 3.84Å; A255-F310 HydrophobicContact CB-CE1 4.48Å; S306-F310 WeakPolarHBondContact O-CB 3.47Å; S306-F310 PolarHBondContact O-N 2.89Å; S306-F310 VanDerWaalsContact O-N 3.11Å; T307-F310 PolarHBondContact O-N 3.06Å; P308-F310 PolarHBondContact O-N 3.21Å; F310-M312 VanDerWaalsContact C-N 3.28Å; F310-M312 PolarHBondContact O-N 3.15Å; F310-N313 WeakPolarHBondContact O-CB 3.27Å; F310-N313 PolarHBondContact O-N 3.47Å; F310-L314 HydrophobicContact CD1-CD1 3.99Å; F310-L314 HydrophobicContact CD1-CG 4.37Å; F310-L314 HydrophobicContact CE1-CD1 3.36Å; F310-L314 HydrophobicContact CE1-CG 4.05Å; F310-L314 HydrophobicContact CZ-CD1 3.92Å; F310-L314 HydrophobicContact CZ-CG 4.4Å; F310-L314 PolarHBondContact O-N 3.26Å; F310-L314 VanDerWaalsContact O-N 3.11Å
311L98.9Very high98.8Very high0 Ų031.6 Ų31.60%018%0.181CC..Hα-helixtrans-62.4-37.6176.5-66-179000111.3V249 A255 L277 T307 P308 L314 L315 L320V249-L311 HydrophobicContact CG1-CD2 4.32Å; A255-L311 HydrophobicContact CB-CD2 3.53Å; L277-L311 HydrophobicContact CD2-CB 3.78Å; T307-L311 HydrophobicContact CG2-CD1 3.93Å; T307-L311 HydrophobicContact CG2-CG 4.14Å; T307-L311 WeakPolarHBondContact O-CG 3.48Å; T307-L311 PolarHBondContact O-N 3.3Å; P308-L311 PolarHBondContact O-N 2.86Å; L311-L314 PolarHBondContact O-N 3.29Å; L311-L315 WeakPolarHBondContact O-CB 3.13Å; L311-L315 PolarHBondContact O-N 2.98Å; L311-L320 HydrophobicContact CB-CD1 4.39Å; L311-L320 HydrophobicContact CD2-CD1 3.96Å
312M98.9Very high98.8Very high1 Ų131.5 Ų31.51%0.00518%0.181CC..Hα-helixtrans-65.4-37.7175.7-168.160.877.600112.4L277 P308 D309 F310 L314 L315 A316 I359 K362 K368 M369L277-M312 HydrophobicContact CB-CE 3.93Å; L277-M312 HydrophobicContact CD1-CE 4.26Å; L277-M312 HydrophobicContact CD2-CB 4.32Å; L277-M312 HydrophobicContact CD2-CE 4Å; L277-M312 HydrophobicContact CD2-SD 4.36Å; L277-M312 HydrophobicContact CG-CE 4.29Å; P308-M312 WeakPolarHBondContact O-CB 3.2Å; P308-M312 PolarHBondContact O-N 2.88Å; D309-M312 PolarHBondContact O-N 3.05Å; F310-M312 VanDerWaalsContact C-N 3.28Å; F310-M312 PolarHBondContact O-N 3.15Å; M312-L314 VanDerWaalsContact C-N 3.33Å; M312-L314 PolarHBondContact O-N 3.4Å; M312-L315 PolarHBondContact O-N 3.49Å; M312-L315 HydrophobicContact SD-CB 4.48Å; M312-L315 HydrophobicContact SD-CD2 3.96Å; M312-A316 WeakPolarHBondContact O-CB 3.32Å; M312-A316 PolarHBondContact O-N 2.96Å; M312-I359 HydrophobicContact CE-CG2 4.34Å; M312-K362 HydrophobicContact CE-CB 3.64Å; M312-K368 HydrophobicContact CB-CD 3.9Å; M312-K368 HydrophobicContact CG-CB 4.49Å; M312-K368 HydrophobicContact CG-CD 3.54Å; M312-M369 HydrophobicContact CG-CE 4.38Å; M312-M369 HydrophobicContact SD-CE 3.51Å; M312-M369 VanDerWaalsContact SD-CE 3.51Å
313N98.9Very high98.8Very high62 Ų6231.4 Ų31.433%0.33218%0.18SC..Hα-helixtrans-62.7-40.9173.4-63.5-35.5000111.4D309 F310 L315 A316 N317 K368D309-N313 VanDerWaalsContact O-CG 3.24Å; D309-N313 PolarHBondContact O-N 3.06Å; D309-N313 PolarHBondContact O-ND2 2.86Å; D309-N313 VanDerWaalsContact O-ND2 3.12Å; D309-N313 PolarHBondContact OD2-ND2 2.97Å; D309-N313 VanDerWaalsContact OD2-ND2 3.12Å; F310-N313 WeakPolarHBondContact O-CB 3.27Å; F310-N313 PolarHBondContact O-N 3.47Å; N313-L315 VanDerWaalsContact C-N 3.32Å; N313-A316 PolarHBondContact O-N 3.13Å; N313-N317 PolarHBondContact O-N 2.82Å; N313-K368 WeakPolarHBondContact OD1-CD 3.37Å; N313-K368 PolarHBondContact OD1-NZ 3.16Å
314L98.9Very high98.8Very high14 Ų1429.3 Ų29.37%0.07317%0.167CC..Hα-helixtrans-72-26.9176.5-62.7-171.8000112.9A255 F310 L311 M312 N317 D318 D319 L320A255-L314 HydrophobicContact CB-CD1 3.5Å; A255-L314 VanDerWaalsContact CB-CD1 3.5Å; F310-L314 HydrophobicContact CD1-CD1 3.99Å; F310-L314 HydrophobicContact CD1-CG 4.37Å; F310-L314 HydrophobicContact CE1-CD1 3.36Å; F310-L314 HydrophobicContact CE1-CG 4.05Å; F310-L314 HydrophobicContact CZ-CD1 3.92Å; F310-L314 HydrophobicContact CZ-CG 4.4Å; F310-L314 PolarHBondContact O-N 3.26Å; F310-L314 VanDerWaalsContact O-N 3.11Å; L311-L314 PolarHBondContact O-N 3.29Å; M312-L314 VanDerWaalsContact C-N 3.33Å; M312-L314 PolarHBondContact O-N 3.4Å; L314-N317 VanDerWaalsContact C-OD1 3.31Å; L314-N317 VanDerWaalsContact CA-OD1 3.24Å; L314-N317 WeakPolarHBondContact CA-OD1 3.42Å; L314-N317 PolarHBondContact O-OD1 2.6Å; L314-D318 PolarHBondContact O-N 3.23Å; L314-D319 HydrophobicContact CB-CB 4.09Å; L314-D319 HydrophobicContact CD2-CB 4.06Å; L314-D319 WeakPolarHBondContact CD2-OD2 3.35Å; L314-D319 PolarHBondContact O-N 2.72Å; L314-D319 VanDerWaalsContact O-N 3.14Å; L314-L320 HydrophobicContact CB-CD1 3.83Å; L314-L320 HydrophobicContact CB-CG 3.87Å; L314-L320 PolarHBondContact O-N 3.15Å
315L98.8Very high98.8Very high0 Ų026.3 Ų26.30%015%0.151CC..Hα-helixtrans-72.3-38.9170.6-171.163.8000111.3P272 L277 L311 M312 N313 L320 T323 M369 R373 V377P272-L315 HydrophobicContact CG-CD1 4.04Å; P272-L315 HydrophobicContact CG-CD2 4.46Å; L277-L315 HydrophobicContact CD1-CD2 3.86Å; L277-L315 HydrophobicContact CD2-CD2 4.47Å; L311-L315 WeakPolarHBondContact O-CB 3.13Å; L311-L315 PolarHBondContact O-N 2.98Å; M312-L315 PolarHBondContact O-N 3.49Å; M312-L315 HydrophobicContact SD-CB 4.48Å; M312-L315 HydrophobicContact SD-CD2 3.96Å; N313-L315 VanDerWaalsContact C-N 3.32Å; L315-L320 HydrophobicContact CB-CB 4.45Å; L315-L320 HydrophobicContact CD1-CB 4.14Å; L315-T323 HydrophobicContact CD1-CG2 4.04Å; L315-T323 HydrophobicContact CD2-CG2 3.42Å; L315-T323 VanDerWaalsContact CD2-CG2 3.42Å; L315-T323 HydrophobicContact CG-CG2 4.37Å; L315-M369 HydrophobicContact CB-CE 4.36Å; L315-M369 HydrophobicContact CD2-CE 4.18Å; L315-M369 HydrophobicContact CG-CE 4.16Å; L315-R373 VanDerWaalsContact O-CZ 3.23Å; L315-R373 PolarHBondContact O-NE 2.88Å; L315-R373 PolarHBondContact O-NH2 2.82Å; L315-V377 HydrophobicContact CD1-CB 3.82Å; L315-V377 HydrophobicContact CD1-CG1 3.7Å; L315-V377 HydrophobicContact CD1-CG2 4.44Å; L315-V377 HydrophobicContact CD2-CB 4.26Å; L315-V377 HydrophobicContact CD2-CG2 3.99Å; L315-V377 HydrophobicContact CG-CB 4.03Å; L315-V377 HydrophobicContact CG-CG1 3.88Å; L315-V377 HydrophobicContact CG-CG2 4.15Å
316A98.9Very high98.8Very high24 Ų2423 Ų2320%0.19813%0.128CC..Hα-helixtrans-65.4-37.1176.500000112.5M312 N313 K368 M369 R373M312-A316 WeakPolarHBondContact O-CB 3.32Å; M312-A316 PolarHBondContact O-N 2.96Å; N313-A316 PolarHBondContact O-N 3.13Å; A316-K368 VanDerWaalsContact CB-O 3.3Å; A316-K368 WeakPolarHBondContact CB-O 3.25Å; A316-M369 HydrophobicContact CB-CB 3.96Å; A316-M369 HydrophobicContact CB-CE 4.05Å; A316-R373 PolarHBondContact O-NE 2.78Å
317N98.6Very high98.8Very high85 Ų8520.2 Ų20.246%0.45511%0.109SC..THydrogen-bonded Turntrans-92.33.4-175.581-1.6000115.3N313 L314 D319N313-N317 PolarHBondContact O-N 2.82Å; L314-N317 VanDerWaalsContact C-OD1 3.31Å; L314-N317 VanDerWaalsContact CA-OD1 3.24Å; L314-N317 WeakPolarHBondContact CA-OD1 3.42Å; L314-N317 PolarHBondContact O-OD1 2.6Å; N317-D319 VanDerWaalsContact C-N 3.31Å; N317-D319 PolarHBondContact ND2-OD2 3.31Å; N317-D319 PolarHBondContact O-N 2.94Å; N317-D319 WeakPolarHBondContact OD1-CB 3.21Å; N317-D319 VanDerWaalsContact OD1-CG 3.31Å; N317-D319 PolarHBondContact OD1-N 3.48Å; N317-D319 PolarHBondContact OD1-OD2 3.26Å
318D98.6Very high98.8Very high43 Ų4320.3 Ų20.323%0.2311%0.11CC..THydrogen-bonded Turntrans69.313.3-178.9-153.566.7000117.1R262 L314 L320 R373R262-D318 PolarHBondContact NE-O 3.3Å; R262-D318 PolarHBondContact NH2-O 3.46Å; R262-D318 VanDerWaalsContact NH2-O 3.13Å; R262-D318 IonicContact NH2-OD2 3.68Å; R262-D318 PolarHBondContact NH2-OD2 2.92Å; L314-D318 PolarHBondContact O-N 3.23Å; D318-L320 VanDerWaalsContact C-N 3.28Å; D318-R373 IonicContact OD1-CZ 2.94Å; D318-R373 IonicContact OD1-NH1 3.19Å; D318-R373 PolarHBondContact OD1-NH1 3.38Å; D318-R373 IonicContact OD1-NH2 3.13Å; D318-R373 PolarHBondContact OD1-NH2 2.93Å
319D98.8Very high98.8Very high16 Ų1619.7 Ų19.79%0.08611%0.106CC..SBendtrans-66.4-36.5163.1-74.3-31.3000110.1A259 R262 R263 L314 N317A259-D319 HydrophobicContact CB-CB 3.8Å; R262-D319 VanDerWaalsContact CD-O 3.29Å; R262-D319 WeakPolarHBondContact CD-O 3.38Å; R263-D319 IonicContact NH2-OD1 3.9Å; R263-D319 IonicContact NH2-OD2 3.37Å; R263-D319 PolarHBondContact NH2-OD2 3.44Å; L314-D319 HydrophobicContact CB-CB 4.09Å; L314-D319 HydrophobicContact CD2-CB 4.06Å; L314-D319 WeakPolarHBondContact CD2-OD2 3.35Å; L314-D319 PolarHBondContact O-N 2.72Å; L314-D319 VanDerWaalsContact O-N 3.14Å; N317-D319 VanDerWaalsContact C-N 3.31Å; N317-D319 PolarHBondContact ND2-OD2 3.31Å; N317-D319 PolarHBondContact O-N 2.94Å; N317-D319 WeakPolarHBondContact OD1-CB 3.21Å; N317-D319 VanDerWaalsContact OD1-CG 3.31Å; N317-D319 PolarHBondContact OD1-N 3.48Å; N317-D319 PolarHBondContact OD1-OD2 3.26Å
320L98.9Very high98.7Very high0 Ų015.8 Ų15.80%09%0.085CC..SBendtrans-109.4142.7165.4-59174.5000109.5V249 A255 I258 P272 L311 L314 L315 D318 R373V249-L320 HydrophobicContact CG1-CD2 4.33Å; V249-L320 HydrophobicContact CG2-CD2 4.34Å; A255-L320 HydrophobicContact CB-CD1 4.21Å; A255-L320 HydrophobicContact CB-CD2 4.32Å; I258-L320 HydrophobicContact CD1-CD2 4.18Å; I258-L320 HydrophobicContact CG2-CD2 4.47Å; P272-L320 HydrophobicContact CB-CD1 4.18Å; P272-L320 HydrophobicContact CG-CB 4.14Å; P272-L320 HydrophobicContact CG-CD1 3.82Å; L311-L320 HydrophobicContact CB-CD1 4.39Å; L311-L320 HydrophobicContact CD2-CD1 3.96Å; L314-L320 HydrophobicContact CB-CD1 3.83Å; L314-L320 HydrophobicContact CB-CG 3.87Å; L314-L320 PolarHBondContact O-N 3.15Å; L315-L320 HydrophobicContact CB-CB 4.45Å; L315-L320 HydrophobicContact CD1-CB 4.14Å; D318-L320 VanDerWaalsContact C-N 3.28Å; L320-R373 PolarHBondContact O-NH2 3.13Å; L320-R373 VanDerWaalsContact O-NH2 3.16Å
321T98.4Very high98.7Very high0 Ų014 Ų140%08%0.079CC..  trans-119.3-25.2-157.551.50000115.2Y269 G270 N381Y269-T321 HydrophobicContact CD1-CG2 4.02Å; G270-T321 PolarHBondContact N-OG1 3.23Å; G270-T321 PolarHBondContact O-N 2.88Å; G270-T321 PolarHBondContact O-OG1 3.1Å; T321-N381 WeakPolarHBondContact O-CB 3.23Å; T321-N381 PolarHBondContact O-ND2 3.08Å
322T98.7Very high98.7Very high0 Ų015.8 Ų15.80%09%0.089CC..  trans-143.8168.8-173.443.30000110Y245 P272 V377 N381 A382 I385Y245-T322 HydrophobicContact CE2-CG2 4.46Å; Y245-T322 WeakPolarHBondContact CE2-OG1 3.31Å; Y245-T322 PolarHBondContact OH-OG1 3.37Å; P272-T322 VanDerWaalsContact CD-O 3.27Å; P272-T322 WeakPolarHBondContact CD-O 3.33Å; T322-V377 CarbonylContact C-O 3.48Å; T322-N381 HydrophobicContact CG2-CB 3.83Å; T322-A382 HydrophobicContact CG2-CB 4.31Å; T322-I385 HydrophobicContact CG2-CD1 3.74Å
323T98.9Very high98.7Very high1 Ų120.1 Ų20.11%0.00612%0.119CC..  trans-132.9132.9172.655.90000110.8T66 P272 L277 L315 R355 I359 V377T66-T323 PolarHBondContact OG1-O 2.96Å; P272-T323 HydrophobicContact CG-CG2 4.48Å; P272-T323 WeakPolarHBondContact O-CA 3.27Å; L277-T323 HydrophobicContact CD1-CG2 3.8Å; L315-T323 HydrophobicContact CD1-CG2 4.04Å; L315-T323 HydrophobicContact CD2-CG2 3.42Å; L315-T323 VanDerWaalsContact CD2-CG2 3.42Å; L315-T323 HydrophobicContact CG-CG2 4.37Å; T323-R355 PolarHBondContact O-NH1 3.45Å; T323-R355 PolarHBondContact OG1-NH1 3.21Å; T323-R355 VanDerWaalsContact OG1-NH1 3.16Å; T323-I359 HydrophobicContact CG2-CD1 3.64Å; T323-I359 HydrophobicContact CG2-CG1 4.46Å; T323-I359 WeakPolarHBondContact OG1-CD1 3.37Å; T323-V377 PolarHBondContact N-O 3.19Å; T323-V377 PolarHBondContact OG1-O 2.92Å
324G98.8Very high98.7Very high0 Ų018.5 Ų18.50%011%0.109CC..BIsolated β-bridgetrans-117.4-166.2167.400000111.1D65 P272 I273 A274D65-G324 WeakPolarHBondContact OD1-CA 3.3Å; P272-G324 PolarHBondContact O-N 2.96Å; I273-G324 VanDerWaalsContact CA-O 3.22Å; I273-G324 WeakPolarHBondContact CA-O 3.43Å; I273-G324 WeakPolarHBondContact CB-O 3.4Å; A274-G324 PolarHBondContact N-O 2.97Å
325T98.9Very high98.6Very high1 Ų117.8 Ų17.81%0.00611%0.106CC..  trans-121.1-24.8172.451.90000114.3D65 H67 A274 N327 G351 R355D65-T325 PolarHBondContact OD1-N 3.22Å; D65-T325 PolarHBondContact OD1-OG1 3.35Å; D65-T325 WeakPolarHBondContact OD2-CB 3.28Å; D65-T325 WeakPolarHBondContact OD2-CG2 3.33Å; D65-T325 PolarHBondContact OD2-OG1 3.33Å; H67-T325 PolarHBondContact O-N 3.04Å; H67-T325 PolarHBondContact O-OG1 2.81Å; A274-T325 HydrophobicContact CB-CG2 4.02Å; T325-N327 PolarHBondContact O-N 2.6Å; T325-N327 VanDerWaalsContact OG1-CB 3.28Å; T325-N327 WeakPolarHBondContact OG1-CB 3.4Å; T325-N327 PolarHBondContact OG1-N 3.43Å; T325-G351 VanDerWaalsContact CG2-O 3.26Å; T325-G351 WeakPolarHBondContact CG2-O 3.49Å; T325-R355 HydrophobicContact CG2-CB 3.68Å; T325-R355 HydrophobicContact CG2-CG 4Å
326D98.5Very high98.6Very high13 Ų1319.5 Ų19.57%0.0712%0.119CC..  trans52.239.5-163.1-167.335.7000110.3H67 H69 H248 I273 M297 C328H67-D326 IonicContact CD2-OD1 3.31Å; H67-D326 PolarHBondContact CD2-OD1 3.29Å; H67-D326 IonicContact CE1-OD1 2.9Å; H67-D326 IonicContact NE2-OD1 2.63Å; H67-D326 PolarHBondContact NE2-OD1 2.86Å; H67-D326 VanDerWaalsContact O-CA 3.28Å; H67-D326 WeakPolarHBondContact O-CA 3.15Å; H67-D326 PolarHBondContact O-N 2.74Å; H69-D326 IonicContact CD2-OD1 2.88Å; H69-D326 PolarHBondContact CD2-OD1 3.48Å; H69-D326 IonicContact NE2-OD1 3.83Å; H69-D326 PolarHBondContact NE2-OD1 3.33Å; H248-D326 IonicContact CD2-OD2 3.14Å; I273-D326 HydrophobicContact CD1-CB 3.95Å; I273-D326 HydrophobicContact CG2-CB 4.3Å; M297-D326 HydrophobicContact CE-CB 3.96Å; M297-D326 WeakPolarHBondContact CE-OD2 3.38Å; D326-C328 PolarHBondContact O-N 3.04Å
327N98.8Very high98.6Very high0 Ų023 Ų230%013%0.134CC..BIsolated β-bridgetrans-61.9105.9-175.3-171.990.6000110H67 T68 H69 T325 G351 V352 Q421H67-N327 PolarHBondContact O-N 3.34Å; T68-N327 HydrophobicContact CG2-CB 4.45Å; H69-N327 CarbonylContact C-O 3.5Å; H69-N327 WeakPolarHBondContact CA-O 3.46Å; H69-N327 PolarHBondContact N-O 3.26Å; T325-N327 PolarHBondContact O-N 2.6Å; T325-N327 VanDerWaalsContact OG1-CB 3.28Å; T325-N327 WeakPolarHBondContact OG1-CB 3.4Å; T325-N327 PolarHBondContact OG1-N 3.43Å; N327-G351 PolarHBondContact OD1-N 2.87Å; N327-G351 VanDerWaalsContact OD1-N 3.1Å; N327-V352 HydrophobicContact CB-CB 4.02Å; N327-V352 PolarHBondContact OD1-N 2.74Å; N327-Q421 PolarHBondContact OD1-OE1 3.35Å
328C98.6Very high98.6Very high5 Ų519 Ų193%0.03411%0.113CC..  trans-146.487.3-176.3-171.10000107.2H69 D326 F330 G348 V349H69-C328 HydrophobicContact CB-CB 3.88Å; D326-C328 PolarHBondContact O-N 3.04Å; C328-F330 VanDerWaalsContact SG-CE2 3.55Å; C328-G348 CarbonylContact O-C 3.54Å; C328-G348 WeakPolarHBondContact O-CA 3.44Å; C328-V349 PolarHBondContact N-O 3.44Å; C328-V349 PolarHBondContact O-N 2.93Å; C328-V349 VanDerWaalsContact O-N 3.16Å
329T98.5Very high98.6Very high0 Ų022.4 Ų22.40%013%0.126CC..  trans-100137.8-162.855.40000112S79 I80 D81 V349 N350 V423S79-T329 CarbonylContact C-O 3.48Å; S79-T329 WeakPolarHBondContact CA-O 3.47Å; S79-T329 PolarHBondContact OG-N 3.43Å; S79-T329 VanDerWaalsContact OG-N 3.13Å; S79-T329 PolarHBondContact OG-O 3.11Å; I80-T329 WeakPolarHBondContact CG2-OG1 3.16Å; I80-T329 PolarHBondContact N-O 3.13Å; D81-T329 WeakPolarHBondContact CB-OG1 3.33Å; D81-T329 VanDerWaalsContact CG-OG1 3.3Å; D81-T329 PolarHBondContact N-OG1 2.9Å; D81-T329 WeakPolarHBondContact OD2-CB 3.19Å; D81-T329 VanDerWaalsContact OD2-CG2 3.23Å; D81-T329 WeakPolarHBondContact OD2-CG2 3.21Å; D81-T329 PolarHBondContact OD2-OG1 3.16Å; T329-V349 WeakPolarHBondContact CG2-O 3.38Å; T329-N350 HydrophobicContact CG2-CB 3.72Å; T329-V423 HydrophobicContact CG2-CB 4.18Å; T329-V423 HydrophobicContact CG2-CG1 3.91Å
330F98.7Very high98.5Very high0 Ų026.8 Ų26.80%015%0.149CC..  trans-132.2126.8176.2-63.2-84.9000107.8F74 C328 Q334 K335 P346 N347 F425F74-F330 HydrophobicContact CB-CZ 4.29Å; F74-F330 HydrophobicContact CD1-CZ 4.24Å; C328-F330 VanDerWaalsContact SG-CE2 3.55Å; F330-Q334 HydrophobicContact CB-CB 3.9Å; F330-Q334 HydrophobicContact CD1-CB 4.33Å; F330-K335 HydrophobicContact CB-CD 4.3Å; F330-K335 HydrophobicContact CB-CG 4.32Å; F330-P346 HydrophobicContact CB-CB 4.34Å; F330-P346 HydrophobicContact CD1-CB 3.63Å; F330-P346 HydrophobicContact CD1-CG 4.22Å; F330-P346 HydrophobicContact CD2-CB 3.66Å; F330-P346 HydrophobicContact CE1-CB 3.73Å; F330-P346 HydrophobicContact CE2-CB 3.76Å; F330-P346 HydrophobicContact CG-CB 3.59Å; F330-P346 HydrophobicContact CG-CG 4.4Å; F330-P346 HydrophobicContact CZ-CB 3.8Å; F330-N347 WeakPolarHBondContact CE2-O 3.36Å; F330-F425 WeakPolarHBondContact O-CE1 3.4Å
331N98.5Very high98.5Very high29 Ų2928 Ų2816%0.15516%0.155CC..  trans-57159.3175.7-84.2-33.7000111.9C333 Q334 K335 V423 N424N331-C333 PolarHBondContact O-N 3.16Å; N331-C333 VanDerWaalsContact O-N 3.07Å; N331-Q334 WeakPolarHBondContact O-CA 3.14Å; N331-Q334 WeakPolarHBondContact O-CB 3.28Å; N331-Q334 PolarHBondContact O-N 3.02Å; N331-K335 PolarHBondContact O-N 3.17Å; N331-V423 WeakPolarHBondContact OD1-CA 3.15Å; N331-N424 PolarHBondContact OD1-N 2.8Å; N331-N424 PolarHBondContact OD1-OD1 3.13Å
332T98.5Very high98.5Very high37 Ų3728 Ų2823%0.22716%0.155CC..Hα-helixtrans-49.8-38.8177.5-55.80000113.1H290 H294 K335 A336 N424H290-T332 HydrophobicContact CB-CG2 3.9Å; H294-T332 PolarHBondContact NE2-OG1 2.94Å; T332-K335 PolarHBondContact O-N 3.13Å; T332-A336 WeakPolarHBondContact O-CB 3.46Å; T332-A336 PolarHBondContact O-N 2.95Å; T332-N424 PolarHBondContact N-OD1 3.16Å; T332-N424 PolarHBondContact OG1-OD1 2.89Å
333C98.2Very high98.5Very high92 Ų9230.3 Ų30.362%0.62217%0.17SC*.Hα-helixtrans-68.4-33.3177600000113.6N331 A336N331-C333 PolarHBondContact O-N 3.16Å; N331-C333 VanDerWaalsContact O-N 3.07Å; C333-A336 PolarHBondContact O-N 3.19Å
334Q98.6Very high98.5Very high28 Ų2835.8 Ų35.813%0.13119%0.193CC..Hα-helixtrans-72.7-40.5173.9-65172.2-75.200110.5S77 R78 F330 N331 A336 L337 P346S77-Q334 PolarHBondContact OG-NE2 2.77Å; R78-Q334 PolarHBondContact O-NE2 2.9Å; F330-Q334 HydrophobicContact CB-CB 3.9Å; F330-Q334 HydrophobicContact CD1-CB 4.33Å; N331-Q334 WeakPolarHBondContact O-CA 3.14Å; N331-Q334 WeakPolarHBondContact O-CB 3.28Å; N331-Q334 PolarHBondContact O-N 3.02Å; Q334-A336 PolarHBondContact O-N 3.3Å; Q334-L337 WeakPolarHBondContact O-CB 3.39Å; Q334-L337 WeakPolarHBondContact O-CD1 3.43Å; Q334-L337 WeakPolarHBondContact O-CG 3.4Å; Q334-L337 PolarHBondContact O-N 3.41Å; Q334-P346 WeakPolarHBondContact O-CD 3.37Å
335K98.6Very high98.5Very high0 Ų035.8 Ų35.80%019%0.193CC..Hα-helixtrans-57.3-39.8172-68.4-70.3-169174.30111.5W289 A293 V296 F330 N331 T332 L337 G338 I345 P346 G348W289-K335 HydrophobicContact CH2-CB 4.48Å; W289-K335 WeakPolarHBondContact CH2-O 3.43Å; A293-K335 HydrophobicContact CB-CB 4.3Å; A293-K335 WeakPolarHBondContact O-CD 3.34Å; A293-K335 WeakPolarHBondContact O-CE 3.33Å; V296-K335 PolarHBondContact O-NZ 2.86Å; F330-K335 HydrophobicContact CB-CD 4.3Å; F330-K335 HydrophobicContact CB-CG 4.32Å; N331-K335 PolarHBondContact O-N 3.17Å; T332-K335 PolarHBondContact O-N 3.13Å; K335-L337 PolarHBondContact O-N 3.45Å; K335-G338 PolarHBondContact O-N 3.33Å; K335-G338 VanDerWaalsContact O-N 3.16Å; K335-I345 HydrophobicContact CB-CG2 4.39Å; K335-I345 HydrophobicContact CD-CG2 3.55Å; K335-P346 PolarHBondContact NZ-O 2.98Å; K335-G348 WeakPolarHBondContact CE-O 3.32Å; K335-G348 PolarHBondContact NZ-O 2.74Å
336A98.4Very high98.4Very high35 Ų3535.7 Ų35.729%0.28919%0.193SC..G310 helixtrans-61.5-8.918000000115.5W289 T332 C333 Q334 G338 K339W289-A336 VanDerWaalsContact CH2-CA 3.49Å; W289-A336 HydrophobicContact CH2-CB 4.33Å; W289-A336 HydrophobicContact CZ3-CB 4.17Å; T332-A336 WeakPolarHBondContact O-CB 3.46Å; T332-A336 PolarHBondContact O-N 2.95Å; C333-A336 PolarHBondContact O-N 3.19Å; Q334-A336 PolarHBondContact O-N 3.3Å; A336-G338 PolarHBondContact O-N 2.99Å; A336-K339 WeakPolarHBondContact O-CB 3.37Å; A336-K339 WeakPolarHBondContact O-CG 3.37Å; A336-K339 PolarHBondContact O-N 2.84Å; A336-K339 VanDerWaalsContact O-N 3.11Å
337L98.3Very high98.4Very high98 Ų9835.8 Ų35.851%0.51319%0.193SC..G310 helixtrans-55.3-29.5168.4-69.2173.4000112.6Q334 K335 P346Q334-L337 WeakPolarHBondContact O-CB 3.39Å; Q334-L337 WeakPolarHBondContact O-CD1 3.43Å; Q334-L337 WeakPolarHBondContact O-CG 3.4Å; Q334-L337 PolarHBondContact O-N 3.41Å; K335-L337 PolarHBondContact O-N 3.45Å; L337-P346 HydrophobicContact CD1-CG 4.21Å
338G98.1Very high98.4Very high0 Ų035.8 Ų35.80%019%0.194CC..G310 helixtrans-104.624.8176.600000115.2K335 A336 D340 D341K335-G338 PolarHBondContact O-N 3.33Å; K335-G338 VanDerWaalsContact O-N 3.16Å; A336-G338 PolarHBondContact O-N 2.99Å; G338-D340 PolarHBondContact O-N 3.14Å; G338-D341 CarbonylContact C-O 3.45Å; G338-D341 WeakPolarHBondContact CA-O 3.41Å; G338-D341 CarbonylContact O-C 3.49Å; G338-D341 PolarHBondContact O-N 3.09Å; G338-D341 VanDerWaalsContact O-N 3.09Å; G338-D341 VanDerWaalsContact O-O 3.1Å
339K98.3Very high98.4Very high115 Ų11535.6 Ų35.650%0.519%0.192SC..THydrogen-bonded Turntrans-57-31.2-17872.4-177.9-172.966.80114.8W289 A336W289-K339 HydrophobicContact CH2-CB 4.27Å; W289-K339 HydrophobicContact CZ2-CB 4Å; W289-K339 PolarHBondContact NE1-O 2.96Å; A336-K339 WeakPolarHBondContact O-CB 3.37Å; A336-K339 WeakPolarHBondContact O-CG 3.37Å; A336-K339 PolarHBondContact O-N 2.84Å; A336-K339 VanDerWaalsContact O-N 3.11Å
340D98.2Very high98.4Very high109 Ų10935.6 Ų35.658%0.58319%0.192SC*.THydrogen-bonded Turntrans-109.84.3179.2-49.7-54.3000112.2T212 G338T212-D340 VanDerWaalsContact CB-O 3.31Å; T212-D340 WeakPolarHBondContact CB-O 3.48Å; T212-D340 WeakPolarHBondContact CG2-O 3.44Å; G338-D340 PolarHBondContact O-N 3.14Å
341D98.6Very high98.4Very high24 Ų2435.6 Ų35.613%0.12819%0.192CC..  trans-163.9100.2-174.9-179.3-11.7000109.8G338 T343 K344G338-D341 CarbonylContact C-O 3.45Å; G338-D341 WeakPolarHBondContact CA-O 3.41Å; G338-D341 CarbonylContact O-C 3.49Å; G338-D341 PolarHBondContact O-N 3.09Å; G338-D341 VanDerWaalsContact O-N 3.09Å; G338-D341 VanDerWaalsContact O-O 3.1Å; D341-T343 PolarHBondContact O-N 3.19Å; D341-T343 WeakPolarHBondContact OD1-CB 3.45Å; D341-T343 PolarHBondContact OD1-N 3.2Å; D341-T343 PolarHBondContact OD1-OG1 3.5Å; D341-T343 PolarHBondContact OD2-OG1 2.81Å; D341-K344 HydrophobicContact CB-CD 4.18Å; D341-K344 HydrophobicContact CB-CG 4.39Å; D341-K344 PolarHBondContact O-N 3.43Å; D341-K344 VanDerWaalsContact OD2-CE 3.32Å; D341-K344 WeakPolarHBondContact OD2-CE 3.34Å; D341-K344 IonicContact OD2-NZ 3.85Å; D341-K344 PolarHBondContact OD2-NZ 3.15Å
342F98.6Very high98.4Very high0 Ų034.2 Ų34.20%019%0.185CC..G310 helixtrans-56.3-25.6-17774.2-94.7000113.8A203 M206 L207 T212 G213 G216 H217 C220 K344 I345A203-F342 HydrophobicContact CB-CE2 4.45Å; A203-F342 HydrophobicContact CB-CZ 4.2Å; M206-F342 HydrophobicContact CB-CE1 3.82Å; M206-F342 HydrophobicContact CB-CZ 3.98Å; L207-F342 HydrophobicContact CD2-CD1 4.12Å; L207-F342 HydrophobicContact CD2-CE1 3.9Å; L207-F342 HydrophobicContact CG-CE1 4.08Å; T212-F342 PolarHBondContact O-N 2.82Å; G213-F342 VanDerWaalsContact O-CB 3.29Å; G213-F342 WeakPolarHBondContact O-CB 3.38Å; G216-F342 WeakPolarHBondContact O-CE2 3.45Å; G216-F342 WeakPolarHBondContact O-CZ 3.29Å; H217-F342 VanDerWaalsContact CA-CD2 3.46Å; H217-F342 HydrophobicContact CB-CD2 3.7Å; H217-F342 HydrophobicContact CB-CE2 4.3Å; H217-F342 HydrophobicContact CB-CG 4.4Å; C220-F342 HydrophobicContact CB-CE2 4.44Å; C220-F342 HydrophobicContact CB-CZ 4.26Å; F342-K344 PolarHBondContact O-N 2.84Å; F342-K344 VanDerWaalsContact O-N 3.17Å; F342-I345 HydrophobicContact CB-CD1 4.14Å; F342-I345 WeakPolarHBondContact O-CB 3.2Å; F342-I345 PolarHBondContact O-N 3.45Å; F342-I345 VanDerWaalsContact O-N 3.13Å
343T98.1Very high98.4Very high49 Ų4932.7 Ų32.730%0.30118%0.175SC..G310 helixtrans-68-15.2179.972.80000112.8M75 A203 L207 D341M75-T343 WeakPolarHBondContact CE-O 3.45Å; A203-T343 HydrophobicContact CB-CG2 4.02Å; L207-T343 HydrophobicContact CD1-CG2 3.89Å; L207-T343 HydrophobicContact CG-CG2 4.46Å; D341-T343 PolarHBondContact O-N 3.19Å; D341-T343 WeakPolarHBondContact OD1-CB 3.45Å; D341-T343 PolarHBondContact OD1-N 3.2Å; D341-T343 PolarHBondContact OD1-OG1 3.5Å; D341-T343 PolarHBondContact OD2-OG1 2.81Å
344K98.3Very high98.4Very high116 Ų11628.3 Ų28.350%0.50415%0.146SC..G310 helixtrans-100.1-1.8177.6-63.3178.4-178.9125.20113.5D341 F342 P346D341-K344 HydrophobicContact CB-CD 4.18Å; D341-K344 HydrophobicContact CB-CG 4.39Å; D341-K344 PolarHBondContact O-N 3.43Å; D341-K344 VanDerWaalsContact OD2-CE 3.32Å; D341-K344 WeakPolarHBondContact OD2-CE 3.34Å; D341-K344 IonicContact OD2-NZ 3.85Å; D341-K344 PolarHBondContact OD2-NZ 3.15Å; F342-K344 PolarHBondContact O-N 2.84Å; F342-K344 VanDerWaalsContact O-N 3.17Å; K344-P346 VanDerWaalsContact O-CD 3.27Å; K344-P346 WeakPolarHBondContact O-CD 3.21Å
345I98.6Very high98.5Very high0 Ų027 Ų270%014%0.14CC..SBendtrans-70.4120.4172.1-58.1174000107.3M75 P214 W289 A293 V296 K335 F342 N347M75-I345 VanDerWaalsContact CE-O 3.31Å; M75-I345 WeakPolarHBondContact CE-O 3.32Å; P214-I345 HydrophobicContact CB-CD1 4.43Å; P214-I345 HydrophobicContact CG-CD1 4.03Å; W289-I345 HydrophobicContact CZ2-CD1 3.9Å; W289-I345 HydrophobicContact CZ2-CG1 4.23Å; A293-I345 HydrophobicContact CB-CD1 4.24Å; V296-I345 HydrophobicContact CB-CG2 3.88Å; V296-I345 HydrophobicContact CG1-CB 4.11Å; V296-I345 HydrophobicContact CG1-CG2 3.83Å; V296-I345 HydrophobicContact CG2-CD1 4.14Å; V296-I345 HydrophobicContact CG2-CG2 4.27Å; K335-I345 HydrophobicContact CB-CG2 4.39Å; K335-I345 HydrophobicContact CD-CG2 3.55Å; F342-I345 HydrophobicContact CB-CD1 4.14Å; F342-I345 WeakPolarHBondContact O-CB 3.2Å; F342-I345 PolarHBondContact O-N 3.45Å; F342-I345 VanDerWaalsContact O-N 3.13Å; I345-N347 PolarHBondContact O-N 3.03Å
346P98Very high98.5Very high0 Ų027 Ų270%014%0.14CC..PPolyproline II helixtrans-57.2123.9174.5-25.736.2000110.7M75 F330 Q334 K335 L337 K344M75-P346 HydrophobicContact CB-CB 4.43Å; F330-P346 HydrophobicContact CB-CB 4.34Å; F330-P346 HydrophobicContact CD1-CB 3.63Å; F330-P346 HydrophobicContact CD1-CG 4.22Å; F330-P346 HydrophobicContact CD2-CB 3.66Å; F330-P346 HydrophobicContact CE1-CB 3.73Å; F330-P346 HydrophobicContact CE2-CB 3.76Å; F330-P346 HydrophobicContact CG-CB 3.59Å; F330-P346 HydrophobicContact CG-CG 4.4Å; F330-P346 HydrophobicContact CZ-CB 3.8Å; Q334-P346 WeakPolarHBondContact O-CD 3.37Å; K335-P346 PolarHBondContact NZ-O 2.98Å; L337-P346 HydrophobicContact CD1-CG 4.21Å; K344-P346 VanDerWaalsContact O-CD 3.27Å; K344-P346 WeakPolarHBondContact O-CD 3.21Å
347N97.9Very high98.5Very high14 Ų1425.3 Ų25.38%0.07513%0.126CC..PPolyproline II helixtrans-77.8129.7-177.4-71.5-82.3000110.9F74 M75 H217 V296 F330 I345F74-N347 HydrophobicContact CE1-CB 4.02Å; M75-N347 HydrophobicContact SD-CB 4.3Å; M75-N347 PolarHBondContact SD-ND2 3.05Å; H217-N347 PolarHBondContact CE1-OD1 2.68Å; H217-N347 PolarHBondContact NE2-OD1 2.77Å; H217-N347 VanDerWaalsContact NE2-OD1 3.15Å; V296-N347 WeakPolarHBondContact CG1-OD1 3.28Å; F330-N347 WeakPolarHBondContact CE2-O 3.36Å; I345-N347 PolarHBondContact O-N 3.03Å
348G98.3Very high98.5Very high1 Ų120.7 Ų20.71%0.0110%0.101CC..  trans148.4154.9174.500000113.1V296 C328 K335V296-G348 PolarHBondContact O-N 2.95Å; C328-G348 CarbonylContact O-C 3.54Å; C328-G348 WeakPolarHBondContact O-CA 3.44Å; K335-G348 WeakPolarHBondContact CE-O 3.32Å; K335-G348 PolarHBondContact NZ-O 2.74Å
349V98.9Very high98.6Very high0 Ų020.7 Ų20.70%010%0.101CC..BIsolated β-bridgetrans-135.2175.5-178.6-60.90000110.7A275 M297 C328 T329 I427A275-V349 HydrophobicContact CB-CG2 3.96Å; M297-V349 HydrophobicContact CB-CG1 4.19Å; M297-V349 HydrophobicContact CE-CG2 3.68Å; M297-V349 HydrophobicContact CG-CG1 4.33Å; M297-V349 HydrophobicContact SD-CB 4.38Å; M297-V349 HydrophobicContact SD-CG1 3.96Å; M297-V349 HydrophobicContact SD-CG2 3.51Å; M297-V349 VanDerWaalsContact SD-CG2 3.51Å; C328-V349 PolarHBondContact N-O 3.44Å; C328-V349 PolarHBondContact O-N 2.93Å; C328-V349 VanDerWaalsContact O-N 3.16Å; T329-V349 WeakPolarHBondContact CG2-O 3.38Å; V349-I427 HydrophobicContact CB-CD1 3.96Å; V349-I427 HydrophobicContact CB-CG2 4.07Å; V349-I427 HydrophobicContact CG1-CD1 4.37Å; V349-I427 HydrophobicContact CG1-CG2 4.03Å; V349-I427 HydrophobicContact CG2-CD1 3.85Å
350N98.8Very high98.6Very high0 Ų015.9 Ų15.90%08%0.08CC..  trans-87.7162174.780-88.6000111T329 Q421 V423 N426 I427T329-N350 HydrophobicContact CG2-CB 3.72Å; N350-Q421 VanDerWaalsContact CB-OE1 3.27Å; N350-V423 HydrophobicContact CB-CG1 3.93Å; N350-N426 PolarHBondContact ND2-ND2 3.19Å; N350-N426 PolarHBondContact ND2-OD1 2.79Å; N350-N426 WeakPolarHBondContact OD1-CA 3.35Å; N350-I427 PolarHBondContact OD1-N 3.49Å
351G98.5Very high98.6Very high0 Ų012.2 Ų12.20%06%0.06CC..  trans171.2-16.6172.300000116.6T325 N327 E353 D354 R355 Q421T325-G351 VanDerWaalsContact CG2-O 3.26Å; T325-G351 WeakPolarHBondContact CG2-O 3.49Å; N327-G351 PolarHBondContact OD1-N 2.87Å; N327-G351 VanDerWaalsContact OD1-N 3.1Å; G351-E353 PolarHBondContact O-N 2.91Å; G351-E353 VanDerWaalsContact O-N 3.16Å; G351-D354 PolarHBondContact O-N 3.36Å; G351-R355 PolarHBondContact O-N 3.33Å; G351-Q421 VanDerWaalsContact N-OE1 3.16Å
352V98.8Very high98.6Very high0 Ų014.8 Ų14.80%07%0.07CC..THydrogen-bonded Turntrans-55.4-37.1-172.670.70000113.7T68 M70 A89 A90 I98 N327 Q421T68-V352 HydrophobicContact CG2-CG2 4.5Å; M70-V352 HydrophobicContact CE-CB 4.47Å; M70-V352 HydrophobicContact CE-CG2 4.06Å; A89-V352 HydrophobicContact CB-CG1 3.77Å; A90-V352 HydrophobicContact CB-CG2 3.61Å; I98-V352 HydrophobicContact CG2-CG2 4.3Å; N327-V352 HydrophobicContact CB-CB 4.02Å; N327-V352 PolarHBondContact OD1-N 2.74Å; V352-Q421 HydrophobicContact CG1-CG 4.25Å
353E98.9Very high98.6Very high6 Ų614.8 Ų14.83%0.0287%0.07CC..THydrogen-bonded Turntrans-80.4-34.3176.9-177.9171.4159.500112.9A89 A92 G93 G351 H419 H420 Q421A89-E353 HydrophobicContact CB-CB 4.15Å; A89-E353 WeakPolarHBondContact O-CA 3.49Å; A89-E353 WeakPolarHBondContact O-CB 3.26Å; A89-E353 WeakPolarHBondContact O-CG 3.43Å; A92-E353 HydrophobicContact CB-CG 4.48Å; G93-E353 WeakPolarHBondContact CA-O 3.32Å; G351-E353 PolarHBondContact O-N 2.91Å; G351-E353 VanDerWaalsContact O-N 3.16Å; E353-H419 WeakPolarHBondContact OE1-CA 3.39Å; E353-H420 IonicContact OE1-CE1 3.97Å; E353-H420 IonicContact OE1-CG 3.54Å; E353-H420 PolarHBondContact OE1-N 2.98Å; E353-H420 IonicContact OE1-ND1 2.78Å; E353-H420 PolarHBondContact OE1-ND1 2.78Å; E353-H420 WeakPolarHBondContact OE2-CA 3.3Å; E353-H420 WeakPolarHBondContact OE2-CB 3.27Å; E353-H420 IonicContact OE2-CG 3.53Å; E353-H420 PolarHBondContact OE2-N 2.88Å; E353-H420 IonicContact OE2-ND1 3.22Å; E353-Q421 HydrophobicContact CB-CG 4.27Å
354D98.8Very high98.7Very high0 Ų013.5 Ų13.50%06%0.061CC..THydrogen-bonded Turntrans-92.6-18.9-167-63.6-53.2000113.4G351 M356 S357 V358 R412 I414 Q421 N426 F428G351-D354 PolarHBondContact O-N 3.36Å; D354-M356 VanDerWaalsContact C-N 3.34Å; D354-M356 PolarHBondContact O-N 3.31Å; D354-S357 PolarHBondContact O-N 3.06Å; D354-S357 VanDerWaalsContact O-N 3.16Å; D354-V358 HydrophobicContact CB-CG2 4.12Å; D354-V358 WeakPolarHBondContact O-CB 3.39Å; D354-V358 WeakPolarHBondContact O-CG2 3.45Å; D354-V358 PolarHBondContact O-N 3.22Å; D354-R412 IonicContact OD1-CZ 3.67Å; D354-R412 VanDerWaalsContact OD1-CZ 3.31Å; D354-R412 IonicContact OD1-NH1 3.45Å; D354-R412 PolarHBondContact OD1-NH1 2.94Å; D354-R412 IonicContact OD1-NH2 3.18Å; D354-R412 PolarHBondContact OD1-NH2 2.63Å; D354-I414 HydrophobicContact CB-CD1 4.02Å; D354-Q421 PolarHBondContact OD2-NE2 3.22Å; D354-N426 PolarHBondContact OD2-ND2 3.3Å; D354-F428 HydrophobicContact CB-CD2 3.85Å; D354-F428 HydrophobicContact CB-CE2 4.14Å
355R98.9Very high98.7Very high0 Ų012.6 Ų12.60%06%0.059CC..Hα-helixtrans-44.2-53.5-175.8-175.3-17464.6113.82.3113.3G63 I64 T95 A274 T323 T325 G351 V358 I359 T378G63-R355 VanDerWaalsContact CA-NH2 3.29Å; I64-R355 PolarHBondContact O-NH1 2.76Å; I64-R355 VanDerWaalsContact O-NH1 3.15Å; T95-R355 PolarHBondContact OG1-NH2 3.16Å; A274-R355 HydrophobicContact CB-CB 4.12Å; A274-R355 HydrophobicContact CB-CG 4.19Å; T323-R355 PolarHBondContact O-NH1 3.45Å; T323-R355 PolarHBondContact OG1-NH1 3.21Å; T323-R355 VanDerWaalsContact OG1-NH1 3.16Å; T325-R355 HydrophobicContact CG2-CB 3.68Å; T325-R355 HydrophobicContact CG2-CG 4Å; G351-R355 PolarHBondContact O-N 3.33Å; R355-V358 PolarHBondContact O-N 3.06Å; R355-I359 HydrophobicContact CG-CD1 3.56Å; R355-I359 WeakPolarHBondContact O-CB 3.27Å; R355-I359 WeakPolarHBondContact O-CD1 3.45Å; R355-I359 WeakPolarHBondContact O-CG1 3.3Å; R355-I359 PolarHBondContact O-N 3.25Å; R355-T378 PolarHBondContact NH1-O 2.7Å; R355-T378 PolarHBondContact NH2-O 3.49Å
356M98.9Very high98.7Very high0 Ų015.7 Ų15.70%08%0.08CC..Hα-helixtrans-64-47-174.4-63.3-67.7-77.200111.6G93 D354 W360 F374 T378 W406G93-M356 VanDerWaalsContact O-CB 3.3Å; G93-M356 WeakPolarHBondContact O-CB 3.42Å; G93-M356 VanDerWaalsContact O-CG 3.27Å; G93-M356 WeakPolarHBondContact O-CG 3.39Å; D354-M356 VanDerWaalsContact C-N 3.34Å; D354-M356 PolarHBondContact O-N 3.31Å; M356-W360 VanDerWaalsContact O-CB 3.3Å; M356-W360 WeakPolarHBondContact O-CB 3.47Å; M356-W360 PolarHBondContact O-N 3.12Å; M356-F374 HydrophobicContact CB-CZ 4.29Å; M356-F374 HydrophobicContact CE-CE1 3.72Å; M356-F374 HydrophobicContact CE-CZ 3.65Å; M356-F374 WeakPolarHBondContact O-CE2 3.49Å; M356-F374 HydrophobicContact SD-CZ 4.17Å; M356-T378 HydrophobicContact CE-CG2 4.49Å; M356-T378 VanDerWaalsContact SD-CB 3.58Å; M356-T378 HydrophobicContact SD-CG2 3.82Å; M356-W406 HydrophobicContact CB-CH2 3.86Å; M356-W406 HydrophobicContact CB-CZ3 3.87Å
357S98.8Very high98.7Very high0 Ų018.8 Ų18.80%011%0.112CC..Hα-helixtrans-70.4-37.7179.3-63.80000112.3D354 W360 E361 R412 G435D354-S357 PolarHBondContact O-N 3.06Å; D354-S357 VanDerWaalsContact O-N 3.16Å; S357-W360 PolarHBondContact O-N 3.12Å; S357-E361 VanDerWaalsContact O-CB 3.27Å; S357-E361 WeakPolarHBondContact O-CB 3.28Å; S357-E361 PolarHBondContact O-N 2.79Å; S357-R412 PolarHBondContact OG-NE 2.99Å; S357-R412 VanDerWaalsContact OG-NE 3.13Å; S357-R412 PolarHBondContact OG-NH2 2.79Å; S357-G435 PolarHBondContact OG-O 2.88Å
358V98.9Very high98.8Very high0 Ų020.7 Ų20.70%012%0.12CC..Hα-helixtrans-62.8-46.7177169.80000110.4D354 R355 W360 E361 K362 I414 F428 M431D354-V358 HydrophobicContact CB-CG2 4.12Å; D354-V358 WeakPolarHBondContact O-CB 3.39Å; D354-V358 WeakPolarHBondContact O-CG2 3.45Å; D354-V358 PolarHBondContact O-N 3.22Å; R355-V358 PolarHBondContact O-N 3.06Å; V358-W360 VanDerWaalsContact C-N 3.35Å; V358-E361 PolarHBondContact O-N 3.01Å; V358-K362 HydrophobicContact CG1-CG 4.42Å; V358-K362 VanDerWaalsContact O-CB 3.31Å; V358-K362 WeakPolarHBondContact O-CB 3.42Å; V358-K362 VanDerWaalsContact O-CG 3.29Å; V358-K362 WeakPolarHBondContact O-CG 3.48Å; V358-K362 PolarHBondContact O-N 2.73Å; V358-I414 HydrophobicContact CG2-CD1 3.88Å; V358-F428 HydrophobicContact CG1-CE1 4.38Å; V358-F428 HydrophobicContact CG2-CD1 4.2Å; V358-F428 HydrophobicContact CG2-CD2 4.14Å; V358-F428 HydrophobicContact CG2-CE1 4.37Å; V358-F428 HydrophobicContact CG2-CE2 4.31Å; V358-F428 HydrophobicContact CG2-CG 4.08Å; V358-F428 HydrophobicContact CG2-CZ 4.42Å; V358-M431 HydrophobicContact CG2-SD 4.08Å
359I98.9Very high98.8Very high0 Ų021.3 Ų21.30%012%0.123CC..Hα-helixtrans-67.4-38.4177.9-62.8163000110.7L277 M312 T323 R355 G363 F374 V377 T378L277-I359 HydrophobicContact CD1-CG1 4.1Å; M312-I359 HydrophobicContact CE-CG2 4.34Å; T323-I359 HydrophobicContact CG2-CD1 3.64Å; T323-I359 HydrophobicContact CG2-CG1 4.46Å; T323-I359 WeakPolarHBondContact OG1-CD1 3.37Å; R355-I359 HydrophobicContact CG-CD1 3.56Å; R355-I359 WeakPolarHBondContact O-CB 3.27Å; R355-I359 WeakPolarHBondContact O-CD1 3.45Å; R355-I359 WeakPolarHBondContact O-CG1 3.3Å; R355-I359 PolarHBondContact O-N 3.25Å; I359-G363 VanDerWaalsContact O-CA 3.26Å; I359-G363 WeakPolarHBondContact O-CA 3.3Å; I359-G363 PolarHBondContact O-N 3.16Å; I359-F374 HydrophobicContact CB-CD2 4.49Å; I359-F374 HydrophobicContact CB-CE2 4.11Å; I359-F374 HydrophobicContact CG2-CD2 3.9Å; I359-F374 HydrophobicContact CG2-CE2 4.01Å; I359-V377 HydrophobicContact CG2-CG2 4.47Å; I359-T378 HydrophobicContact CD1-CG2 3.93Å; I359-T378 HydrophobicContact CG2-CG2 4.29Å
360W98.9Very high98.8Very high14 Ų1425.3 Ų25.35%0.05314%0.144CC..Iπ-helixtrans-61.4-50.6175.4-177.9-79.9000111.6L58 M356 S357 V358 V364 H365 E371 F374 W406 P408 H434L58-W360 HydrophobicContact CD1-CH2 3.43Å; L58-W360 VanDerWaalsContact CD1-CH2 3.43Å; L58-W360 HydrophobicContact CD1-CZ2 4.4Å; L58-W360 HydrophobicContact CD1-CZ3 3.92Å; M356-W360 VanDerWaalsContact O-CB 3.3Å; M356-W360 WeakPolarHBondContact O-CB 3.47Å; M356-W360 PolarHBondContact O-N 3.12Å; S357-W360 PolarHBondContact O-N 3.12Å; V358-W360 VanDerWaalsContact C-N 3.35Å; W360-V364 HydrophobicContact CD2-CB 3.95Å; W360-V364 HydrophobicContact CD2-CG1 4.23Å; W360-V364 HydrophobicContact CD2-CG2 4.17Å; W360-V364 HydrophobicContact CE3-CB 4.15Å; W360-V364 HydrophobicContact CE3-CG1 4.32Å; W360-V364 HydrophobicContact CE3-CG2 3.91Å; W360-V364 HydrophobicContact CG-CB 4.32Å; W360-V364 HydrophobicContact CH2-CB 4.5Å; W360-V364 HydrophobicContact CH2-CG1 3.79Å; W360-V364 HydrophobicContact CZ2-CB 4.35Å; W360-V364 HydrophobicContact CZ2-CG1 3.71Å; W360-V364 HydrophobicContact CZ3-CB 4.43Å; W360-V364 HydrophobicContact CZ3-CG1 4.12Å; W360-V364 HydrophobicContact CZ3-CG2 4.18Å; W360-V364 CarbonylContact O-C 3.6Å; W360-V364 WeakPolarHBondContact O-CA 3.49Å; W360-V364 WeakPolarHBondContact O-CB 3.25Å; W360-V364 PolarHBondContact O-N 3.49Å; W360-H365 PolarHBondContact O-N 3.42Å; W360-E371 HydrophobicContact CH2-CB 4.24Å; W360-E371 HydrophobicContact CZ3-CB 4.27Å; W360-F374 HydrophobicContact CB-CD2 4.46Å; W360-F374 HydrophobicContact CB-CE2 3.9Å; W360-F374 HydrophobicContact CB-CZ 4.34Å; W360-F374 AromaticContact CE3-CD1 3.91Å; W360-F374 HydrophobicContact CE3-CD1 3.91Å; W360-F374 HydrophobicContact CE3-CD2 4.13Å; W360-F374 AromaticContact CE3-CE1 3.94Å; W360-F374 HydrophobicContact CE3-CE1 3.94Å; W360-F374 HydrophobicContact CE3-CE2 4.17Å; W360-F374 HydrophobicContact CE3-CG 4Å; W360-F374 HydrophobicContact CE3-CZ 4.07Å; W360-F374 HydrophobicContact CZ3-CD1 4.11Å; W360-F374 HydrophobicContact CZ3-CE1 4.42Å; W360-F374 HydrophobicContact CZ3-CG 4.37Å; W360-W406 HydrophobicContact CB-CH2 4.43Å; W360-W406 HydrophobicContact CB-CZ2 3.66Å; W360-W406 AromaticContact CD2-CE2 3.85Å; W360-W406 AromaticContact CD2-CZ2 3.85Å; W360-W406 HydrophobicContact CD2-CZ2 3.85Å; W360-W406 AromaticContact CD2-NE1 3.35Å; W360-W406 VanDerWaalsContact CD2-NE1 3.35Å; W360-W406 AromaticContact CE2-NE1 3.58Å; W360-W406 AromaticContact CE3-CE2 3.83Å; W360-W406 HydrophobicContact CE3-CZ2 4.04Å; W360-W406 AromaticContact CE3-NE1 3.34Å; W360-W406 VanDerWaalsContact CE3-NE1 3.34Å; W360-W406 AromaticContact CG-CZ2 3.68Å; W360-W406 HydrophobicContact CG-CZ2 3.68Å; W360-W406 AromaticContact CH2-NE1 3.88Å; W360-W406 AromaticContact CZ2-NE1 3.86Å; W360-W406 AromaticContact CZ3-NE1 3.61Å; W360-P408 HydrophobicContact CH2-CB 3.97Å; W360-P408 HydrophobicContact CZ2-CB 3.37Å; W360-H434 VanDerWaalsContact CD1-C 3.46Å
361E98.9Very high98.8Very high33 Ų3327.5 Ų27.515%0.15416%0.155CC..Iπ-helixtrans-60.1-51.3179.3176.758.6-149.300111.2S357 V358 H365 S366 C433 H434S357-E361 VanDerWaalsContact O-CB 3.27Å; S357-E361 WeakPolarHBondContact O-CB 3.28Å; S357-E361 PolarHBondContact O-N 2.79Å; V358-E361 PolarHBondContact O-N 3.01Å; E361-H365 IonicContact OE1-CD2 2.89Å; E361-H365 PolarHBondContact OE1-CD2 2.67Å; E361-H365 IonicContact OE2-CD2 3.08Å; E361-H365 IonicContact OE2-CG 2.73Å; E361-S366 PolarHBondContact O-N 3.18Å; E361-C433 HydrophobicContact CB-CB 4.02Å; E361-C433 HydrophobicContact CG-CB 4.44Å; E361-C433 WeakPolarHBondContact OE2-CA 3.35Å; E361-H434 IonicContact OE1-ND1 3.52Å; E361-H434 IonicContact OE2-CE1 2.85Å; E361-H434 IonicContact OE2-CG 3.97Å; E361-H434 PolarHBondContact OE2-N 2.9Å; E361-H434 IonicContact OE2-ND1 3.6Å; E361-H434 PolarHBondContact OE2-ND1 3.22Å
362K98.8Very high98.8Very high78 Ų7828.7 Ų28.734%0.33916%0.161SC..Iπ-helixtrans-79.7-22.5-174.1-60.9-61.6-174-176.30113.5M312 V358 S366M312-K362 HydrophobicContact CE-CB 3.64Å; V358-K362 HydrophobicContact CG1-CG 4.42Å; V358-K362 VanDerWaalsContact O-CB 3.31Å; V358-K362 WeakPolarHBondContact O-CB 3.42Å; V358-K362 VanDerWaalsContact O-CG 3.29Å; V358-K362 WeakPolarHBondContact O-CG 3.48Å; V358-K362 PolarHBondContact O-N 2.73Å; K362-S366 VanDerWaalsContact C-OG 3.28Å; K362-S366 WeakPolarHBondContact O-CB 3.45Å; K362-S366 PolarHBondContact O-OG 3.11Å
363G98.8Very high98.8Very high0 Ų030.6 Ų30.60%017%0.168CC..Iπ-helixtrans-107.1-56.2-176.500000114.1I359 S366 K368 M369I359-G363 VanDerWaalsContact O-CA 3.26Å; I359-G363 WeakPolarHBondContact O-CA 3.3Å; I359-G363 PolarHBondContact O-N 3.16Å; G363-S366 PolarHBondContact O-OG 2.99Å; G363-K368 WeakPolarHBondContact O-CB 3.23Å; G363-K368 PolarHBondContact O-N 2.97Å; G363-M369 PolarHBondContact O-N 2.69Å
364V98.9Very high98.8Very high21 Ų2130.3 Ų30.313%0.12717%0.167CC..Iπ-helixtrans-82.9-54.1-174.1-177.30000111.5W360 S366 G367 M369 F374W360-V364 HydrophobicContact CD2-CB 3.95Å; W360-V364 HydrophobicContact CD2-CG1 4.23Å; W360-V364 HydrophobicContact CD2-CG2 4.17Å; W360-V364 HydrophobicContact CE3-CB 4.15Å; W360-V364 HydrophobicContact CE3-CG1 4.32Å; W360-V364 HydrophobicContact CE3-CG2 3.91Å; W360-V364 HydrophobicContact CG-CB 4.32Å; W360-V364 HydrophobicContact CH2-CB 4.5Å; W360-V364 HydrophobicContact CH2-CG1 3.79Å; W360-V364 HydrophobicContact CZ2-CB 4.35Å; W360-V364 HydrophobicContact CZ2-CG1 3.71Å; W360-V364 HydrophobicContact CZ3-CB 4.43Å; W360-V364 HydrophobicContact CZ3-CG1 4.12Å; W360-V364 HydrophobicContact CZ3-CG2 4.18Å; W360-V364 CarbonylContact O-C 3.6Å; W360-V364 WeakPolarHBondContact O-CA 3.49Å; W360-V364 WeakPolarHBondContact O-CB 3.25Å; W360-V364 PolarHBondContact O-N 3.49Å; V364-S366 PolarHBondContact O-N 3.12Å; V364-G367 PolarHBondContact O-N 3.07Å; V364-M369 WeakPolarHBondContact CA-O 3.31Å; V364-M369 HydrophobicContact CG2-CG 4.05Å; V364-F374 HydrophobicContact CG2-CB 3.62Å; V364-F374 HydrophobicContact CG2-CD2 4.01Å; V364-F374 HydrophobicContact CG2-CG 4.02Å
365H98.7Very high98.8Very high98 Ų9830.3 Ų30.345%0.45417%0.167SC..Iπ-helixtrans-62.1-34.1-178.5-178.268.6000112.1W360 E361 G367 H434W360-H365 PolarHBondContact O-N 3.42Å; E361-H365 IonicContact OE1-CD2 2.89Å; E361-H365 PolarHBondContact OE1-CD2 2.67Å; E361-H365 IonicContact OE2-CD2 3.08Å; E361-H365 IonicContact OE2-CG 2.73Å; H365-G367 VanDerWaalsContact C-N 3.25Å; H365-G367 PolarHBondContact O-N 3.36Å; H365-H434 HydrophobicContact CB-CB 4.44Å; H365-H434 AromaticContact CD2-CE1 3.88Å; H365-H434 AromaticContact CD2-ND1 3.44Å; H365-H434 PolarHBondContact CD2-ND1 3.3Å; H365-H434 AromaticContact CE1-CD2 3.92Å; H365-H434 AromaticContact CE1-CE1 3.5Å; H365-H434 PolarHBondContact CE1-CE1 3.42Å; H365-H434 VanDerWaalsContact CE1-CE1 3.5Å; H365-H434 AromaticContact CE1-CG 3.76Å; H365-H434 AromaticContact CE1-ND1 3.5Å; H365-H434 PolarHBondContact CE1-ND1 2.91Å; H365-H434 AromaticContact CE1-NE2 3.78Å; H365-H434 AromaticContact CG-CG 3.98Å; H365-H434 AromaticContact CG-ND1 3.7Å; H365-H434 AromaticContact ND1-CG 3.72Å; H365-H434 AromaticContact ND1-ND1 3.73Å; H365-H434 AromaticContact NE2-CE1 3.3Å; H365-H434 PolarHBondContact NE2-CE1 2.92Å; H365-H434 VanDerWaalsContact NE2-CE1 3.3Å; H365-H434 AromaticContact NE2-ND1 3.34Å; H365-H434 PolarHBondContact NE2-ND1 3.48Å
366S98.4Very high98.8Very high64 Ų6430.6 Ų30.645%0.44817%0.169SC..THydrogen-bonded Turntrans-73.7-9.717571.50000114.7E361 K362 G363 V364E361-S366 PolarHBondContact O-N 3.18Å; K362-S366 VanDerWaalsContact C-OG 3.28Å; K362-S366 WeakPolarHBondContact O-CB 3.45Å; K362-S366 PolarHBondContact O-OG 3.11Å; G363-S366 PolarHBondContact O-OG 2.99Å; V364-S366 PolarHBondContact O-N 3.12Å
367G98.5Very high98.8Very high65 Ų6530.7 Ų30.767%0.6717%0.17SC*.THydrogen-bonded Turntrans79.615.2-179.900000115.4V364 H365V364-G367 PolarHBondContact O-N 3.07Å; H365-G367 VanDerWaalsContact C-N 3.25Å; H365-G367 PolarHBondContact O-N 3.36Å
368K98.7Very high98.8Very high54 Ų5430.7 Ų30.724%0.23517%0.17CC..SBendtrans-77.2-33.6176.6-68.2179.2-177.6-62.50113.1D309 M312 N313 A316 G363D309-K368 WeakPolarHBondContact OD1-CE 3.5Å; D309-K368 IonicContact OD1-NZ 3.46Å; D309-K368 PolarHBondContact OD1-NZ 2.67Å; D309-K368 IonicContact OD2-NZ 3.37Å; D309-K368 PolarHBondContact OD2-NZ 3.4Å; M312-K368 HydrophobicContact CB-CD 3.9Å; M312-K368 HydrophobicContact CG-CB 4.49Å; M312-K368 HydrophobicContact CG-CD 3.54Å; N313-K368 WeakPolarHBondContact OD1-CD 3.37Å; N313-K368 PolarHBondContact OD1-NZ 3.16Å; A316-K368 VanDerWaalsContact CB-O 3.3Å; A316-K368 WeakPolarHBondContact CB-O 3.25Å; G363-K368 WeakPolarHBondContact O-CB 3.23Å; G363-K368 PolarHBondContact O-N 2.97Å
369M98.6Very high98.8Very high15 Ų1530.7 Ų30.77%0.07417%0.17CC..SBendtrans-141.9159.217773.9179.968.500110.8M312 L315 A316 G363 V364 R373 F374 V377M312-M369 HydrophobicContact CG-CE 4.38Å; M312-M369 HydrophobicContact SD-CE 3.51Å; M312-M369 VanDerWaalsContact SD-CE 3.51Å; L315-M369 HydrophobicContact CB-CE 4.36Å; L315-M369 HydrophobicContact CD2-CE 4.18Å; L315-M369 HydrophobicContact CG-CE 4.16Å; A316-M369 HydrophobicContact CB-CB 3.96Å; A316-M369 HydrophobicContact CB-CE 4.05Å; G363-M369 PolarHBondContact O-N 2.69Å; V364-M369 WeakPolarHBondContact CA-O 3.31Å; V364-M369 HydrophobicContact CG2-CG 4.05Å; M369-R373 HydrophobicContact CB-CB 3.91Å; M369-R373 HydrophobicContact CB-CG 3.79Å; M369-R373 HydrophobicContact CG-CB 4.39Å; M369-R373 HydrophobicContact CG-CG 4.33Å; M369-R373 HydrophobicContact SD-CB 4.35Å; M369-R373 HydrophobicContact SD-CG 3.9Å; M369-F374 HydrophobicContact SD-CB 4.47Å; M369-V377 HydrophobicContact SD-CG2 4.14Å
370D98.8Very high98.8Very high84 Ų8430.7 Ų30.745%0.44917%0.17SC..  trans-88.3177174.658.828.3000112.2N372 R373 F374D370-N372 PolarHBondContact O-N 2.85Å; D370-N372 PolarHBondContact OD1-N 2.92Å; D370-N372 VanDerWaalsContact OD1-N 3.16Å; D370-R373 PolarHBondContact O-N 2.81Å; D370-R373 WeakPolarHBondContact OD1-CB 3.47Å; D370-R373 PolarHBondContact OD1-N 2.79Å; D370-F374 PolarHBondContact O-N 2.91Å
371E98.8Very high98.8Very high46 Ų4630.4 Ų30.422%0.21517%0.169CC..Hα-helixtrans-63.3-26.8178.165.3-100.5-147.300113.6R13 V15 L58 W360 F374 V375R13-E371 IonicContact NH1-OE1 3.93Å; V15-E371 HydrophobicContact CB-CG 4.44Å; V15-E371 HydrophobicContact CG1-CB 3.94Å; V15-E371 HydrophobicContact CG1-CG 3.53Å; V15-E371 HydrophobicContact CG2-CG 4.01Å; L58-E371 HydrophobicContact CD1-CB 4.29Å; W360-E371 HydrophobicContact CH2-CB 4.24Å; W360-E371 HydrophobicContact CZ3-CB 4.27Å; E371-F374 WeakPolarHBondContact O-CB 3.43Å; E371-V375 WeakPolarHBondContact O-CG2 3.36Å; E371-V375 PolarHBondContact O-N 3.46Å; E371-V375 VanDerWaalsContact O-N 3.12Å
372N98.9Very high98.8Very high25 Ų2528.9 Ų28.913%0.13416%0.163CC..Hα-helixtrans-74.5-44.5-179.1-60.6101.9000110.4N16 D17 F19 S20 D370 F374 V375 A376N16-N372 WeakPolarHBondContact O-CA 3.39Å; N16-N372 PolarHBondContact O-ND2 3.35Å; D17-N372 WeakPolarHBondContact CA-O 3.42Å; F19-N372 PolarHBondContact O-ND2 3.06Å; S20-N372 PolarHBondContact OG-ND2 3.29Å; S20-N372 PolarHBondContact OG-OD1 2.8Å; D370-N372 PolarHBondContact O-N 2.85Å; D370-N372 PolarHBondContact OD1-N 2.92Å; D370-N372 VanDerWaalsContact OD1-N 3.16Å; N372-F374 VanDerWaalsContact C-N 3.29Å; N372-F374 PolarHBondContact O-N 2.87Å; N372-V375 PolarHBondContact O-N 3.44Å; N372-A376 PolarHBondContact O-N 3.41Å
373R98.9Very high98.8Very high39 Ų3925.2 Ų25.215%0.14715%0.146CC..Hα-helixtrans-64.2-35.7172.8-177.462.9-1721695.3111.6L315 A316 D318 L320 M369 D370 V375 A376 V377L315-R373 VanDerWaalsContact O-CZ 3.23Å; L315-R373 PolarHBondContact O-NE 2.88Å; L315-R373 PolarHBondContact O-NH2 2.82Å; A316-R373 PolarHBondContact O-NE 2.78Å; D318-R373 IonicContact OD1-CZ 2.94Å; D318-R373 IonicContact OD1-NH1 3.19Å; D318-R373 PolarHBondContact OD1-NH1 3.38Å; D318-R373 IonicContact OD1-NH2 3.13Å; D318-R373 PolarHBondContact OD1-NH2 2.93Å; L320-R373 PolarHBondContact O-NH2 3.13Å; L320-R373 VanDerWaalsContact O-NH2 3.16Å; M369-R373 HydrophobicContact CB-CB 3.91Å; M369-R373 HydrophobicContact CB-CG 3.79Å; M369-R373 HydrophobicContact CG-CB 4.39Å; M369-R373 HydrophobicContact CG-CG 4.33Å; M369-R373 HydrophobicContact SD-CB 4.35Å; M369-R373 HydrophobicContact SD-CG 3.9Å; D370-R373 PolarHBondContact O-N 2.81Å; D370-R373 WeakPolarHBondContact OD1-CB 3.47Å; D370-R373 PolarHBondContact OD1-N 2.79Å; R373-V375 PolarHBondContact O-N 3.22Å; R373-A376 WeakPolarHBondContact O-CB 3.33Å; R373-A376 PolarHBondContact O-N 3.01Å; R373-A376 VanDerWaalsContact O-N 3.16Å; R373-V377 HydrophobicContact CG-CG1 4.46Å; R373-V377 VanDerWaalsContact CZ-CG1 3.44Å; R373-V377 WeakPolarHBondContact O-CG2 3.23Å; R373-V377 PolarHBondContact O-N 3.25Å
374F98.9Very high98.8Very high0 Ų027.1 Ų27.10%016%0.155CC..Hα-helixtrans-56.7-48.3171.3173.7-96.7000111.9L60 M356 I359 W360 V364 M369 D370 E371 N372 A376 V377 T378 W406L60-F374 HydrophobicContact CD1-CD1 4.18Å; L60-F374 HydrophobicContact CD1-CE1 3.75Å; M356-F374 HydrophobicContact CB-CZ 4.29Å; M356-F374 HydrophobicContact CE-CE1 3.72Å; M356-F374 HydrophobicContact CE-CZ 3.65Å; M356-F374 WeakPolarHBondContact O-CE2 3.49Å; M356-F374 HydrophobicContact SD-CZ 4.17Å; I359-F374 HydrophobicContact CB-CD2 4.49Å; I359-F374 HydrophobicContact CB-CE2 4.11Å; I359-F374 HydrophobicContact CG2-CD2 3.9Å; I359-F374 HydrophobicContact CG2-CE2 4.01Å; W360-F374 HydrophobicContact CB-CD2 4.46Å; W360-F374 HydrophobicContact CB-CE2 3.9Å; W360-F374 HydrophobicContact CB-CZ 4.34Å; W360-F374 AromaticContact CE3-CD1 3.91Å; W360-F374 HydrophobicContact CE3-CD1 3.91Å; W360-F374 HydrophobicContact CE3-CD2 4.13Å; W360-F374 AromaticContact CE3-CE1 3.94Å; W360-F374 HydrophobicContact CE3-CE1 3.94Å; W360-F374 HydrophobicContact CE3-CE2 4.17Å; W360-F374 HydrophobicContact CE3-CG 4Å; W360-F374 HydrophobicContact CE3-CZ 4.07Å; W360-F374 HydrophobicContact CZ3-CD1 4.11Å; W360-F374 HydrophobicContact CZ3-CE1 4.42Å; W360-F374 HydrophobicContact CZ3-CG 4.37Å; V364-F374 HydrophobicContact CG2-CB 3.62Å; V364-F374 HydrophobicContact CG2-CD2 4.01Å; V364-F374 HydrophobicContact CG2-CG 4.02Å; M369-F374 HydrophobicContact SD-CB 4.47Å; D370-F374 PolarHBondContact O-N 2.91Å; E371-F374 WeakPolarHBondContact O-CB 3.43Å; N372-F374 VanDerWaalsContact C-N 3.29Å; N372-F374 PolarHBondContact O-N 2.87Å; F374-A376 VanDerWaalsContact C-N 3.29Å; F374-A376 PolarHBondContact O-N 3.03Å; F374-V377 PolarHBondContact O-N 3.07Å; F374-T378 HydrophobicContact CD2-CG2 3.99Å; F374-T378 HydrophobicContact CE1-CG2 4.48Å; F374-T378 HydrophobicContact CE2-CG2 3.73Å; F374-T378 HydrophobicContact CG-CG2 4.48Å; F374-T378 HydrophobicContact CZ-CG2 4Å; F374-T378 WeakPolarHBondContact O-CB 3.38Å; F374-T378 WeakPolarHBondContact O-CG2 3.22Å; F374-T378 PolarHBondContact O-N 3.17Å; F374-T378 PolarHBondContact O-OG1 3.17Å; F374-W406 HydrophobicContact CZ-CZ2 4.49Å
375V98.9Very high98.8Very high1 Ų126.1 Ų26.11%0.00615%0.149CC..Hα-helixtrans-60.5-40.2174.9170.30000111.4V15 L60 P61 E371 N372 R373 V377 S379 T380V15-V375 HydrophobicContact CB-CG2 4.34Å; V15-V375 HydrophobicContact CG1-CG2 3.83Å; L60-V375 HydrophobicContact CB-CG2 4.43Å; L60-V375 HydrophobicContact CD2-CG2 3.98Å; P61-V375 HydrophobicContact CG-CG1 3.79Å; E371-V375 WeakPolarHBondContact O-CG2 3.36Å; E371-V375 PolarHBondContact O-N 3.46Å; E371-V375 VanDerWaalsContact O-N 3.12Å; N372-V375 PolarHBondContact O-N 3.44Å; R373-V375 PolarHBondContact O-N 3.22Å; V375-V377 PolarHBondContact O-N 2.92Å; V375-S379 PolarHBondContact O-N 3.08Å; V375-T380 PolarHBondContact O-N 3.08Å; V375-T380 VanDerWaalsContact O-N 3.07Å
376A98.9Very high98.8Very high6 Ų621.5 Ų21.55%0.0513%0.127CC..Iπ-helixtrans-58.3-51178.100000112.2D17 N372 R373 F374 T380 N381D17-A376 HydrophobicContact CB-CB 3.89Å; N372-A376 PolarHBondContact O-N 3.41Å; R373-A376 WeakPolarHBondContact O-CB 3.33Å; R373-A376 PolarHBondContact O-N 3.01Å; R373-A376 VanDerWaalsContact O-N 3.16Å; F374-A376 VanDerWaalsContact C-N 3.29Å; F374-A376 PolarHBondContact O-N 3.03Å; A376-T380 PolarHBondContact O-N 3.02Å; A376-N381 WeakPolarHBondContact O-CB 3.43Å; A376-N381 VanDerWaalsContact O-CG 3.23Å; A376-N381 PolarHBondContact O-N 3.04Å; A376-N381 PolarHBondContact O-ND2 3.16Å
377V98.9Very high98.9Very high1 Ų121 Ų211%0.00612%0.119CC..Iπ-helixtrans-83.5-16.3-172.2-57.70000114.3L315 T322 T323 I359 M369 R373 F374 V375L315-V377 HydrophobicContact CD1-CB 3.82Å; L315-V377 HydrophobicContact CD1-CG1 3.7Å; L315-V377 HydrophobicContact CD1-CG2 4.44Å; L315-V377 HydrophobicContact CD2-CB 4.26Å; L315-V377 HydrophobicContact CD2-CG2 3.99Å; L315-V377 HydrophobicContact CG-CB 4.03Å; L315-V377 HydrophobicContact CG-CG1 3.88Å; L315-V377 HydrophobicContact CG-CG2 4.15Å; T322-V377 CarbonylContact C-O 3.48Å; T323-V377 PolarHBondContact N-O 3.19Å; T323-V377 PolarHBondContact OG1-O 2.92Å; I359-V377 HydrophobicContact CG2-CG2 4.47Å; M369-V377 HydrophobicContact SD-CG2 4.14Å; R373-V377 HydrophobicContact CG-CG1 4.46Å; R373-V377 VanDerWaalsContact CZ-CG1 3.44Å; R373-V377 WeakPolarHBondContact O-CG2 3.23Å; R373-V377 PolarHBondContact O-N 3.25Å; F374-V377 PolarHBondContact O-N 3.07Å; V375-V377 PolarHBondContact O-N 2.92Å
378T98.9Very high98.9Very high1 Ų118.3 Ų18.31%0.0069%0.09CC..Iπ-helixtrans-101.1-15.7179.160.20000114.1I64 R355 M356 I359 F374I64-T378 PolarHBondContact N-O 3.32Å; R355-T378 PolarHBondContact NH1-O 2.7Å; R355-T378 PolarHBondContact NH2-O 3.49Å; M356-T378 HydrophobicContact CE-CG2 4.49Å; M356-T378 VanDerWaalsContact SD-CB 3.58Å; M356-T378 HydrophobicContact SD-CG2 3.82Å; I359-T378 HydrophobicContact CD1-CG2 3.93Å; I359-T378 HydrophobicContact CG2-CG2 4.29Å; F374-T378 HydrophobicContact CD2-CG2 3.99Å; F374-T378 HydrophobicContact CE1-CG2 4.48Å; F374-T378 HydrophobicContact CE2-CG2 3.73Å; F374-T378 HydrophobicContact CG-CG2 4.48Å; F374-T378 HydrophobicContact CZ-CG2 4Å; F374-T378 WeakPolarHBondContact O-CB 3.38Å; F374-T378 WeakPolarHBondContact O-CG2 3.22Å; F374-T378 PolarHBondContact O-N 3.17Å; F374-T378 PolarHBondContact O-OG1 3.17Å
379S98.9Very high98.9Very high0 Ų019.6 Ų19.60%09%0.094CC..Iπ-helixtrans-148.7-61.4-177-162.50000113.5G62 V375 N381 A382 A383 G393G62-S379 WeakPolarHBondContact O-CB 3.49Å; G62-S379 PolarHBondContact O-OG 3.31Å; V375-S379 PolarHBondContact O-N 3.08Å; S379-N381 PolarHBondContact O-N 3.4Å; S379-A382 WeakPolarHBondContact O-CB 3.48Å; S379-A382 PolarHBondContact O-N 2.99Å; S379-A383 PolarHBondContact O-N 3.05Å; S379-G393 WeakPolarHBondContact OG-CA 3.12Å
380T98.9Very high98.9Very high0 Ų022 Ų220%011%0.111CC..Iπ-helixtrans-63.7-42.3-166-50.80000114D17 V375 A376 A383 K384 Y389 G393D17-T380 HydrophobicContact CB-CG2 4.09Å; D17-T380 WeakPolarHBondContact OD2-CG2 3.01Å; V375-T380 PolarHBondContact O-N 3.08Å; V375-T380 VanDerWaalsContact O-N 3.07Å; A376-T380 PolarHBondContact O-N 3.02Å; T380-A383 PolarHBondContact O-N 3.36Å; T380-K384 HydrophobicContact CG2-CD 4.04Å; T380-K384 VanDerWaalsContact CG2-CE 3.45Å; T380-K384 HydrophobicContact CG2-CG 4.39Å; T380-K384 WeakPolarHBondContact O-CG 3.5Å; T380-K384 PolarHBondContact O-N 3.21Å; T380-Y389 HydrophobicContact CG2-CD2 3.77Å; T380-Y389 HydrophobicContact CG2-CE2 3.6Å; T380-G393 WeakPolarHBondContact CB-O 3.42Å; T380-G393 PolarHBondContact OG1-O 2.75Å
381N98.9Very high98.9Very high7 Ų722.6 Ų22.64%0.03711%0.107CC..Hα-helixtrans-66.8-39.2-179.8-70.5-14.6000111.4T321 T322 A376 S379 A383 K384 I385T321-N381 WeakPolarHBondContact O-CB 3.23Å; T321-N381 PolarHBondContact O-ND2 3.08Å; T322-N381 HydrophobicContact CG2-CB 3.83Å; A376-N381 WeakPolarHBondContact O-CB 3.43Å; A376-N381 VanDerWaalsContact O-CG 3.23Å; A376-N381 PolarHBondContact O-N 3.04Å; A376-N381 PolarHBondContact O-ND2 3.16Å; S379-N381 PolarHBondContact O-N 3.4Å; N381-A383 VanDerWaalsContact C-N 3.34Å; N381-K384 PolarHBondContact O-N 3.29Å; N381-I385 WeakPolarHBondContact O-CB 3.49Å; N381-I385 VanDerWaalsContact O-CG1 3.24Å; N381-I385 WeakPolarHBondContact O-CG1 3.47Å; N381-I385 PolarHBondContact O-N 2.7Å
382A98.9Very high98.9Very high2 Ų220.7 Ų20.72%0.01710%0.098CC..Hα-helixtrans-59.8-46.3172.400000110.8I64 T66 T322 S379 K384 I385 F386I64-A382 HydrophobicContact CB-CB 4.05Å; I64-A382 HydrophobicContact CG2-CB 3.95Å; T66-A382 HydrophobicContact CG2-CB 3.34Å; T322-A382 HydrophobicContact CG2-CB 4.31Å; S379-A382 WeakPolarHBondContact O-CB 3.48Å; S379-A382 PolarHBondContact O-N 2.99Å; A382-K384 VanDerWaalsContact C-N 3.34Å; A382-K384 PolarHBondContact O-N 2.99Å; A382-I385 PolarHBondContact O-N 3.12Å; A382-F386 HydrophobicContact CB-CD2 4.48Å; A382-F386 WeakPolarHBondContact O-CB 3.47Å; A382-F386 VanDerWaalsContact O-CD2 3.28Å; A382-F386 WeakPolarHBondContact O-CD2 3.5Å; A382-F386 PolarHBondContact O-N 3.29Å
383A98.9Very high98.9Very high0 Ų019.7 Ų19.70%09%0.094CC..Hα-helixtrans-61.7-39.7176.900000112.5I64 S379 T380 N381 N387 L388 Y389 K392I64-A383 HydrophobicContact CD1-CB 3.82Å; S379-A383 PolarHBondContact O-N 3.05Å; T380-A383 PolarHBondContact O-N 3.36Å; N381-A383 VanDerWaalsContact C-N 3.34Å; A383-N387 PolarHBondContact O-N 2.88Å; A383-N387 VanDerWaalsContact O-N 3.11Å; A383-L388 HydrophobicContact CB-CB 4.14Å; A383-L388 PolarHBondContact O-N 3.23Å; A383-Y389 PolarHBondContact O-N 3.48Å; A383-Y389 VanDerWaalsContact O-N 3.1Å; A383-K392 VanDerWaalsContact CB-O 3.27Å; A383-K392 WeakPolarHBondContact CB-O 3.39Å
384K98.9Very high98.9Very high40 Ų4019.9 Ų19.917%0.1749%0.094CC..Hα-helixtrans-68.1-46.1177.1-72.4170.9-178.4162.50112D17 T380 N381 A382 N387 Y389 Y471D17-K384 IonicContact OD2-NZ 3.4Å; D17-K384 PolarHBondContact OD2-NZ 3.1Å; T380-K384 HydrophobicContact CG2-CD 4.04Å; T380-K384 VanDerWaalsContact CG2-CE 3.45Å; T380-K384 HydrophobicContact CG2-CG 4.39Å; T380-K384 WeakPolarHBondContact O-CG 3.5Å; T380-K384 PolarHBondContact O-N 3.21Å; N381-K384 PolarHBondContact O-N 3.29Å; A382-K384 VanDerWaalsContact C-N 3.34Å; A382-K384 PolarHBondContact O-N 2.99Å; K384-N387 PolarHBondContact O-N 2.9Å; K384-Y389 HydrophobicContact CG-CD1 4.09Å; K384-Y389 HydrophobicContact CG-CD2 4.08Å; K384-Y389 HydrophobicContact CG-CG 3.71Å; K384-Y471 HydrophobicContact CB-CD1 3.76Å; K384-Y471 HydrophobicContact CB-CD2 4.02Å; K384-Y471 HydrophobicContact CB-CE1 4.15Å; K384-Y471 HydrophobicContact CB-CE2 4.4Å; K384-Y471 HydrophobicContact CB-CG 3.68Å; K384-Y471 HydrophobicContact CD-CD2 4.08Å; K384-Y471 HydrophobicContact CD-CE2 4.01Å; K384-Y471 HydrophobicContact CG-CD2 4.41Å
385I98.9Very high98.8Very high1 Ų120 Ų201%0.00510%0.095CC..Hα-helixtrans-64.7-46.1-179.4-71.8169.5000110.8I188 Y245 Y269 T322 N381 A382 N387 Y471 I472I188-I385 HydrophobicContact CD1-CG2 3.86Å; Y245-I385 HydrophobicContact CD2-CD1 4.45Å; Y245-I385 HydrophobicContact CD2-CG2 4.08Å; Y245-I385 HydrophobicContact CE2-CD1 4.13Å; Y245-I385 HydrophobicContact CE2-CG2 4.2Å; Y269-I385 HydrophobicContact CD1-CD1 3.57Å; Y269-I385 HydrophobicContact CD1-CG1 4.12Å; Y269-I385 HydrophobicContact CE1-CD1 4.04Å; Y269-I385 HydrophobicContact CE1-CG1 4.11Å; Y269-I385 HydrophobicContact CG-CD1 3.99Å; T322-I385 HydrophobicContact CG2-CD1 3.74Å; N381-I385 WeakPolarHBondContact O-CB 3.49Å; N381-I385 VanDerWaalsContact O-CG1 3.24Å; N381-I385 WeakPolarHBondContact O-CG1 3.47Å; N381-I385 PolarHBondContact O-N 2.7Å; A382-I385 PolarHBondContact O-N 3.12Å; I385-N387 VanDerWaalsContact C-N 3.31Å; I385-N387 PolarHBondContact O-N 3.45Å; I385-Y471 HydrophobicContact CG1-CD1 3.93Å; I385-Y471 HydrophobicContact CG1-CE1 3.73Å; I385-I472 HydrophobicContact CB-CD1 4.41Å; I385-I472 HydrophobicContact CG2-CD1 4.06Å; I385-I472 WeakPolarHBondContact O-CD1 3.5Å
386F98.9Very high98.8Very high0 Ų021 Ų210%010%0.103CC..THydrogen-bonded Turntrans-91.912.3-176.9-60.4-61.9000113.8T66 I99 H132 N156 I188 Y245 A382 L388 R465T66-F386 HydrophobicContact CG2-CD2 4.02Å; T66-F386 HydrophobicContact CG2-CE2 3.54Å; I99-F386 HydrophobicContact CD1-CB 4.17Å; I99-F386 HydrophobicContact CD1-CD2 3.65Å; I99-F386 HydrophobicContact CD1-CE2 4.25Å; I99-F386 HydrophobicContact CD1-CG 3.91Å; H132-F386 AromaticContact CE1-CD1 3.79Å; H132-F386 AromaticContact CE1-CE1 3.41Å; H132-F386 VanDerWaalsContact CE1-CE1 3.41Å; H132-F386 WeakPolarHBondContact CE1-CE1 3.43Å; H132-F386 AromaticContact CE1-CZ 3.64Å; N156-F386 PolarHBondContact ND2-O 2.91Å; I188-F386 HydrophobicContact CG2-CD1 4.24Å; I188-F386 HydrophobicContact CG2-CE1 3.87Å; Y245-F386 HydrophobicContact CD2-CZ 4.33Å; Y245-F386 HydrophobicContact CE2-CE2 4.29Å; Y245-F386 AromaticContact CE2-CZ 3.99Å; Y245-F386 HydrophobicContact CE2-CZ 3.99Å; A382-F386 HydrophobicContact CB-CD2 4.48Å; A382-F386 WeakPolarHBondContact O-CB 3.47Å; A382-F386 VanDerWaalsContact O-CD2 3.28Å; A382-F386 WeakPolarHBondContact O-CD2 3.5Å; A382-F386 PolarHBondContact O-N 3.29Å; F386-L388 HydrophobicContact CB-CD1 4.48Å; F386-R465 WeakPolarHBondContact O-CB 3.32Å; F386-R465 VanDerWaalsContact O-CD 3.32Å; F386-R465 WeakPolarHBondContact O-CD 3.18Å
387N98.8Very high98.8Very high53 Ų5325.4 Ų25.428%0.28313%0.13SC..THydrogen-bonded Turntrans62.645.1172.2-151.219.3000115.3A383 K384 I385 K466 P467 A469A383-N387 PolarHBondContact O-N 2.88Å; A383-N387 VanDerWaalsContact O-N 3.11Å; K384-N387 PolarHBondContact O-N 2.9Å; I385-N387 VanDerWaalsContact C-N 3.31Å; I385-N387 PolarHBondContact O-N 3.45Å; N387-K466 PolarHBondContact ND2-O 3.11Å; N387-P467 PolarHBondContact ND2-O 2.83Å; N387-A469 HydrophobicContact CB-CB 3.73Å
388L98.8Very high98.8Very high9 Ų927.8 Ų27.85%0.04715%0.154CC..  trans-114.6-8.8177.1-60.8167.1000112.5M97 A383 F386 R391 K392 I463 R465M97-L388 HydrophobicContact CE-CD1 3.6Å; M97-L388 HydrophobicContact SD-CD1 3.66Å; A383-L388 HydrophobicContact CB-CB 4.14Å; A383-L388 PolarHBondContact O-N 3.23Å; F386-L388 HydrophobicContact CB-CD1 4.48Å; L388-R391 CarbonylContact O-C 3.5Å; L388-R391 WeakPolarHBondContact O-CA 3.27Å; L388-R391 VanDerWaalsContact O-CB 3.27Å; L388-R391 WeakPolarHBondContact O-CB 3.49Å; L388-R391 PolarHBondContact O-N 2.74Å; L388-K392 HydrophobicContact CB-CB 4.35Å; L388-K392 PolarHBondContact O-N 3.44Å; L388-I463 HydrophobicContact CD2-CB 4.46Å; L388-I463 HydrophobicContact CD2-CG2 3.44Å; L388-I463 VanDerWaalsContact CD2-CG2 3.44Å; L388-R465 HydrophobicContact CD2-CG 3.98Å; L388-R465 HydrophobicContact CG-CG 4.42Å
389Y98.8Very high98.8Very high81 Ų8127.9 Ų27.932%0.31816%0.155SC..THydrogen-bonded Turntrans-81.9141.7-177.7-178.1-91.6000112.3T380 A383 K384 R394T380-Y389 HydrophobicContact CG2-CD2 3.77Å; T380-Y389 HydrophobicContact CG2-CE2 3.6Å; A383-Y389 PolarHBondContact O-N 3.48Å; A383-Y389 VanDerWaalsContact O-N 3.1Å; K384-Y389 HydrophobicContact CG-CD1 4.09Å; K384-Y389 HydrophobicContact CG-CD2 4.08Å; K384-Y389 HydrophobicContact CG-CG 3.71Å; Y389-R394 HydrophobicContact CE2-CB 3.93Å; Y389-R394 HydrophobicContact CE2-CG 4.43Å; Y389-R394 WeakPolarHBondContact OH-CD 3.48Å; Y389-R394 PolarHBondContact OH-NH1 3.01Å
390P98.6Very high98.8Very high67 Ų6729 Ų2944%0.43516%0.161SC..THydrogen-bonded Turncis-90.110.5-2.237.4-36.3000113.6K392 R394 S399P390-K392 PolarHBondContact O-N 2.63Å; P390-R394 HydrophobicContact CB-CB 4.39Å; P390-S399 WeakPolarHBondContact O-CB 3.45Å; P390-S399 PolarHBondContact O-OG 2.99Å
391R98.6Very high98.7Very high96 Ų9629 Ų2936%0.36216%0.161SC..THydrogen-bonded Turntrans-55.5-39.7178.4177.5-177.9172.9-161.2-11.4111.3L388 D400L388-R391 CarbonylContact O-C 3.5Å; L388-R391 WeakPolarHBondContact O-CA 3.27Å; L388-R391 VanDerWaalsContact O-CB 3.27Å; L388-R391 WeakPolarHBondContact O-CB 3.49Å; L388-R391 PolarHBondContact O-N 2.74Å; R391-D400 HydrophobicContact CG-CB 4.47Å; R391-D400 WeakPolarHBondContact CG-OD1 3.28Å; R391-D400 IonicContact CZ-OD1 3.63Å; R391-D400 IonicContact CZ-OD2 2.79Å; R391-D400 VanDerWaalsContact NE-CG 3.33Å; R391-D400 IonicContact NE-OD1 3.32Å; R391-D400 PolarHBondContact NE-OD1 2.97Å; R391-D400 IonicContact NE-OD2 2.96Å; R391-D400 PolarHBondContact NE-OD2 3.22Å; R391-D400 IonicContact NH2-OD1 3.05Å; R391-D400 IonicContact NH2-OD2 2.74Å; R391-D400 PolarHBondContact NH2-OD2 3.29Å; R391-D400 VanDerWaalsContact NH2-OD2 3.08Å; R391-D400 WeakPolarHBondContact O-CB 3.36Å; R391-D400 PolarHBondContact O-N 3.18Å
392K98.9Very high98.7Very high5 Ų529.2 Ų29.22%0.02216%0.162CC..SBendtrans-122162.2169.3-60.7-169.7-178.9-54.30110.9I64 M97 D128 A383 L388 P390 R394 D400 D402I64-K392 HydrophobicContact CD1-CB 3.98Å; M97-K392 HydrophobicContact CB-CD 4.45Å; M97-K392 HydrophobicContact CG-CD 4.45Å; M97-K392 HydrophobicContact SD-CD 3.29Å; M97-K392 WeakPolarHBondContact SD-CD 3.43Å; M97-K392 VanDerWaalsContact SD-CE 3.52Å; D128-K392 IonicContact OD2-NZ 2.89Å; D128-K392 PolarHBondContact OD2-NZ 3.28Å; A383-K392 VanDerWaalsContact CB-O 3.27Å; A383-K392 WeakPolarHBondContact CB-O 3.39Å; L388-K392 HydrophobicContact CB-CB 4.35Å; L388-K392 PolarHBondContact O-N 3.44Å; P390-K392 PolarHBondContact O-N 2.63Å; K392-R394 VanDerWaalsContact C-N 3.3Å; K392-R394 PolarHBondContact O-N 2.93Å; K392-D400 IonicContact NZ-OD2 2.67Å; K392-D400 PolarHBondContact NZ-OD2 3.04Å; K392-D402 IonicContact NZ-OD2 3.66Å; K392-D402 PolarHBondContact NZ-OD2 2.93Å
393G98.6Very high98.7Very high5 Ų529.2 Ų29.25%0.05216%0.162CC..SBendtrans71.32217800000115S379 T380S379-G393 WeakPolarHBondContact OG-CA 3.12Å; T380-G393 WeakPolarHBondContact CB-O 3.42Å; T380-G393 PolarHBondContact OG1-O 2.75Å
394R98.8Very high98.7Very high42 Ų4229.2 Ų29.216%0.15816%0.162CC..  trans-153.1141.8170.4-166.1173.1-175.381.41.6110.5N16 D17 D18 Y389 P390 K392 A396 S399N16-R394 WeakPolarHBondContact OD1-CA 3.46Å; N16-R394 WeakPolarHBondContact OD1-CG 3.31Å; D17-R394 IonicContact OD1-NH1 3.02Å; D17-R394 PolarHBondContact OD1-NH1 3.39Å; D18-R394 VanDerWaalsContact CG-NH1 3.33Å; D18-R394 IonicContact OD1-CZ 3.03Å; D18-R394 IonicContact OD1-NH1 3.8Å; D18-R394 PolarHBondContact OD1-NH1 3.07Å; D18-R394 IonicContact OD1-NH2 3.65Å; D18-R394 PolarHBondContact OD1-NH2 3.16Å; D18-R394 IonicContact OD2-CZ 3.26Å; D18-R394 IonicContact OD2-NH1 3.87Å; D18-R394 PolarHBondContact OD2-NH1 2.86Å; D18-R394 IonicContact OD2-NH2 3.17Å; D18-R394 PolarHBondContact OD2-NH2 3.45Å; Y389-R394 HydrophobicContact CE2-CB 3.93Å; Y389-R394 HydrophobicContact CE2-CG 4.43Å; Y389-R394 WeakPolarHBondContact OH-CD 3.48Å; Y389-R394 PolarHBondContact OH-NH1 3.01Å; P390-R394 HydrophobicContact CB-CB 4.39Å; K392-R394 VanDerWaalsContact C-N 3.3Å; K392-R394 PolarHBondContact O-N 2.93Å; R394-A396 HydrophobicContact CG-CB 4.03Å; R394-S399 WeakPolarHBondContact O-CB 2.81Å; R394-S399 PolarHBondContact O-OG 3.45Å
395I98.8Very high98.7Very high2 Ų227.5 Ų27.51%0.0115%0.154CC..  trans-91.9100.6163.7-63165000107V14 N16 V25 L35 V59 L60 P61 I403V14-I395 HydrophobicContact CG1-CB 3.85Å; V14-I395 HydrophobicContact CG1-CD1 3.94Å; V14-I395 HydrophobicContact CG1-CG2 3.79Å; N16-I395 PolarHBondContact ND2-O 3.18Å; N16-I395 PolarHBondContact OD1-N 3.11Å; V25-I395 HydrophobicContact CG1-CG2 4.11Å; V25-I395 HydrophobicContact CG2-CG2 4.03Å; L35-I395 HydrophobicContact CD1-CG2 4.3Å; V59-I395 HydrophobicContact CB-CD1 4.37Å; V59-I395 HydrophobicContact CG1-CD1 3.81Å; V59-I395 WeakPolarHBondContact O-CD1 3.43Å; L60-I395 VanDerWaalsContact C-CD1 3.45Å; P61-I395 HydrophobicContact CG-CG1 4.17Å; I395-I403 HydrophobicContact CD1-CG2 4.27Å; I395-I403 HydrophobicContact CG1-CG1 4.32Å
396A98.5Very high98.7Very high23 Ų2327.4 Ų27.419%0.1915%0.154CC..SBendtrans-150.2156.6176.400000109.8V32 R394 G398 S399V32-A396 VanDerWaalsContact CB-O 3.31Å; V32-A396 WeakPolarHBondContact CB-O 3.38Å; R394-A396 HydrophobicContact CG-CB 4.03Å; A396-G398 PolarHBondContact O-N 3.2Å; A396-S399 VanDerWaalsContact O-CB 3.29Å; A396-S399 WeakPolarHBondContact O-CB 3.49Å; A396-S399 PolarHBondContact O-N 3.09Å; A396-S399 PolarHBondContact O-OG 3.49Å
397V98.6Very high98.7Very high99 Ų9928.7 Ų28.760%0.616%0.161SC*.THydrogen-bonded Turntrans-56.3127.3175.2177.10000109.8V32V32-V397 WeakPolarHBondContact O-CA 3.38Å
398G98.3Very high98.6Very high51 Ų5127.8 Ų27.853%0.52616%0.158SC..THydrogen-bonded Turntrans91.7-9.7-177.400000115.3V32 A396V32-G398 PolarHBondContact O-N 3.24Å; A396-G398 PolarHBondContact O-N 3.2Å
399S98.8Very high98.6Very high2 Ų235.8 Ų35.81%0.01419%0.192CC..SBendtrans-73.8152.3172.1-61.70000111.7V31 V32 P390 R394 A396 A401V31-S399 WeakPolarHBondContact CA-O 3.45Å; V31-S399 WeakPolarHBondContact CG1-O 3.37Å; V32-S399 PolarHBondContact N-O 3.45Å; P390-S399 WeakPolarHBondContact O-CB 3.45Å; P390-S399 PolarHBondContact O-OG 2.99Å; R394-S399 WeakPolarHBondContact O-CB 2.81Å; R394-S399 PolarHBondContact O-OG 3.45Å; A396-S399 VanDerWaalsContact O-CB 3.29Å; A396-S399 WeakPolarHBondContact O-CB 3.49Å; A396-S399 PolarHBondContact O-N 3.09Å; A396-S399 PolarHBondContact O-OG 3.49Å; S399-A401 PolarHBondContact O-N 3.35Å
400D98.8Very high98.5Very high25 Ų2533.1 Ų33.113%0.13419%0.187CC..BIsolated β-bridgetrans-58137170-70.5-3000108.3R391 K392 D402R391-D400 HydrophobicContact CG-CB 4.47Å; R391-D400 WeakPolarHBondContact CG-OD1 3.28Å; R391-D400 IonicContact CZ-OD1 3.63Å; R391-D400 IonicContact CZ-OD2 2.79Å; R391-D400 VanDerWaalsContact NE-CG 3.33Å; R391-D400 IonicContact NE-OD1 3.32Å; R391-D400 PolarHBondContact NE-OD1 2.97Å; R391-D400 IonicContact NE-OD2 2.96Å; R391-D400 PolarHBondContact NE-OD2 3.22Å; R391-D400 IonicContact NH2-OD1 3.05Å; R391-D400 IonicContact NH2-OD2 2.74Å; R391-D400 PolarHBondContact NH2-OD2 3.29Å; R391-D400 VanDerWaalsContact NH2-OD2 3.08Å; R391-D400 WeakPolarHBondContact O-CB 3.36Å; R391-D400 PolarHBondContact O-N 3.18Å; K392-D400 IonicContact NZ-OD2 2.67Å; K392-D400 PolarHBondContact NZ-OD2 3.04Å; D400-D402 PolarHBondContact O-N 3.22Å
401A98.5Very high98.4Very high0 Ų034 Ų340%019%0.191CC..  trans-80.364.7178.500000111.3V27 G30 V32 S399 I403 I441 R443 G444V27-A401 HydrophobicContact CB-CB 4.14Å; V27-A401 HydrophobicContact CG1-CB 3.31Å; V27-A401 HydrophobicContact CG2-CB 3.69Å; G30-A401 WeakPolarHBondContact O-CB 3.48Å; G30-A401 PolarHBondContact O-N 3.45Å; V32-A401 HydrophobicContact CG2-CB 4.42Å; S399-A401 PolarHBondContact O-N 3.35Å; A401-I403 HydrophobicContact CB-CD1 4.48Å; A401-I441 WeakPolarHBondContact O-CG2 3.36Å; A401-R443 PolarHBondContact O-N 2.94Å; A401-G444 PolarHBondContact O-N 3.23Å
402D98.8Very high98.4Very high10 Ų1031.8 Ų31.85%0.05318%0.183CC..  trans-10494.1172-67.2-23.4000108.1G62 T96 K392 D400 I441 R443G62-D402 PolarHBondContact N-O 2.69Å; T96-D402 HydrophobicContact CG2-CB 4.31Å; K392-D402 IonicContact NZ-OD2 3.66Å; K392-D402 PolarHBondContact NZ-OD2 2.93Å; D400-D402 PolarHBondContact O-N 3.22Å; D402-I441 CarbonylContact C-O 3.57Å; D402-I441 VanDerWaalsContact CA-O 3.32Å; D402-I441 WeakPolarHBondContact CA-O 3.32Å; D402-R443 PolarHBondContact OD1-N 3.39Å
403I98.9Very high98.4Very high2 Ų235.5 Ų35.51%0.0121%0.206CC..EExtended strand (participates in β ladder)trans-135.5142.6-162.6-58.6173.8000110I9 V25 V27 V32 V59 L60 I395 A401 I441I9-I403 HydrophobicContact CD1-CB 4.26Å; I9-I403 HydrophobicContact CD1-CD1 3.94Å; I9-I403 HydrophobicContact CD1-CG2 3.62Å; V25-I403 HydrophobicContact CG1-CD1 3.98Å; V27-I403 HydrophobicContact CG2-CD1 4.12Å; V32-I403 HydrophobicContact CG2-CD1 4Å; V59-I403 HydrophobicContact CG1-CG2 3.38Å; L60-I403 WeakPolarHBondContact O-CA 3.43Å; I395-I403 HydrophobicContact CD1-CG2 4.27Å; I395-I403 HydrophobicContact CG1-CG1 4.32Å; A401-I403 HydrophobicContact CB-CD1 4.48Å; I403-I441 HydrophobicContact CB-CB 4.32Å; I403-I441 HydrophobicContact CB-CD1 4.34Å; I403-I441 PolarHBondContact N-O 3.21Å; I403-I441 WeakPolarHBondContact O-CA 3.2Å; I403-I441 WeakPolarHBondContact O-CB 3.36Å; I403-I441 PolarHBondContact O-N 3.21Å
404V98.9Very high98.4Very high0 Ų035.2 Ų35.20%020%0.203CC..EExtended strand (participates in β ladder)trans-118.2128.6173.8179.40000109.7V59 L60 G94 W406 P437 V439 T440V59-V404 WeakPolarHBondContact CA-O 3.32Å; L60-V404 PolarHBondContact N-O 2.78Å; L60-V404 PolarHBondContact O-N 3.18Å; G94-V404 VanDerWaalsContact O-CG2 3.28Å; G94-V404 WeakPolarHBondContact O-CG2 3.39Å; V404-W406 HydrophobicContact CG1-CB 4.32Å; V404-W406 HydrophobicContact CG1-CE3 4.09Å; V404-P437 HydrophobicContact CG1-CB 3.82Å; V404-V439 WeakPolarHBondContact CA-O 3.43Å; V404-T440 HydrophobicContact CG2-CG2 4.29Å
405I98.8Very high98.4Very high4 Ų434 Ų342%0.02120%0.201CC..EExtended strand (participates in β ladder)trans-86.9110.1163.6-55.9178.1000106.6I9 L52 A54 K57 L58 L438 V439I9-I405 HydrophobicContact CG2-CD1 3.91Å; I9-I405 HydrophobicContact CG2-CG1 4.17Å; L52-I405 HydrophobicContact CB-CD1 3.85Å; L52-I405 HydrophobicContact CD1-CD1 4.1Å; A54-I405 HydrophobicContact CB-CD1 4.32Å; A54-I405 HydrophobicContact CB-CG2 4.04Å; K57-I405 HydrophobicContact CB-CG2 3.81Å; K57-I405 HydrophobicContact CG-CG2 4.11Å; L58-I405 CarbonylContact O-C 3.54Å; L58-I405 WeakPolarHBondContact O-CA 3.26Å; I405-L438 PolarHBondContact O-N 3.22Å; I405-V439 HydrophobicContact CB-CB 4.01Å; I405-V439 HydrophobicContact CB-CG2 4.31Å; I405-V439 HydrophobicContact CD1-CB 4.02Å; I405-V439 HydrophobicContact CD1-CG2 4.08Å; I405-V439 HydrophobicContact CG1-CB 4.15Å; I405-V439 PolarHBondContact N-O 2.88Å; I405-V439 PolarHBondContact O-N 3.27Å
406W98.8Very high98.4Very high0 Ų035.1 Ų35.10%021%0.211CC..EExtended strand (participates in β ladder)trans-109.2128.2-171.2-176.9-92.1000110.7K57 L58 L60 M356 W360 F374 V404 P408 G435 P437K57-W406 WeakPolarHBondContact CB-O 3.29Å; L58-W406 HydrophobicContact CB-CB 4.25Å; L58-W406 PolarHBondContact N-O 3.3Å; L58-W406 PolarHBondContact O-N 2.98Å; L60-W406 HydrophobicContact CD1-CB 3.77Å; L60-W406 HydrophobicContact CD1-CD2 4.22Å; L60-W406 HydrophobicContact CD1-CG 3.85Å; L60-W406 HydrophobicContact CG-CB 4.07Å; M356-W406 HydrophobicContact CB-CH2 3.86Å; M356-W406 HydrophobicContact CB-CZ3 3.87Å; W360-W406 HydrophobicContact CB-CH2 4.43Å; W360-W406 HydrophobicContact CB-CZ2 3.66Å; W360-W406 AromaticContact CD2-CE2 3.85Å; W360-W406 AromaticContact CD2-CZ2 3.85Å; W360-W406 HydrophobicContact CD2-CZ2 3.85Å; W360-W406 AromaticContact CD2-NE1 3.35Å; W360-W406 VanDerWaalsContact CD2-NE1 3.35Å; W360-W406 AromaticContact CE2-NE1 3.58Å; W360-W406 AromaticContact CE3-CE2 3.83Å; W360-W406 HydrophobicContact CE3-CZ2 4.04Å; W360-W406 AromaticContact CE3-NE1 3.34Å; W360-W406 VanDerWaalsContact CE3-NE1 3.34Å; W360-W406 AromaticContact CG-CZ2 3.68Å; W360-W406 HydrophobicContact CG-CZ2 3.68Å; W360-W406 AromaticContact CH2-NE1 3.88Å; W360-W406 AromaticContact CZ2-NE1 3.86Å; W360-W406 AromaticContact CZ3-NE1 3.61Å; F374-W406 HydrophobicContact CZ-CZ2 4.49Å; V404-W406 HydrophobicContact CG1-CB 4.32Å; V404-W406 HydrophobicContact CG1-CE3 4.09Å; W406-P408 WeakPolarHBondContact O-CD 3.49Å; W406-G435 VanDerWaalsContact CE2-C 3.46Å; W406-G435 VanDerWaalsContact CE2-CA 3.42Å; W406-G435 VanDerWaalsContact CH2-O 3.27Å; W406-G435 WeakPolarHBondContact CH2-O 3.46Å; W406-G435 WeakPolarHBondContact CZ2-O 3.45Å; W406-P437 HydrophobicContact CE3-CB 4.14Å; W406-P437 HydrophobicContact CZ3-CB 4.21Å; W406-P437 HydrophobicContact CZ3-CG 4.28Å
407D98.4Very high98.4Very high27 Ų2743.2 Ų43.214%0.14424%0.242CC..EExtended strand (participates in β ladder)trans-96.8106.2172.5-167.7-23.8000110.4K57 K409 A410 G435 V436 L438K57-D407 HydrophobicContact CD-CB 3.78Å; K57-D407 WeakPolarHBondContact CE-OD2 3.43Å; D407-K409 PolarHBondContact O-N 2.87Å; D407-K409 PolarHBondContact OD1-N 2.9Å; D407-A410 HydrophobicContact CB-CB 3.66Å; D407-A410 PolarHBondContact OD1-N 2.84Å; D407-A410 VanDerWaalsContact OD1-N 3.1Å; D407-G435 VanDerWaalsContact O-CA 3.23Å; D407-G435 WeakPolarHBondContact O-CA 3.13Å; D407-V436 PolarHBondContact N-O 2.79Å; D407-V436 PolarHBondContact O-N 2.81Å; D407-L438 HydrophobicContact CB-CD1 3.77Å; D407-L438 HydrophobicContact CB-CD2 4.03Å; D407-L438 HydrophobicContact CB-CG 3.75Å
408P97.7Very high98.3Very high33 Ų3342.8 Ų42.821%0.21424%0.239CC..EExtended strand (participates in β ladder)trans-71.4-12.9-178.831.6-36.5000113.4L58 W360 W406L58-P408 HydrophobicContact CD1-CB 4.32Å; L58-P408 HydrophobicContact CD1-CG 4.41Å; L58-P408 HydrophobicContact CG-CG 4.22Å; W360-P408 HydrophobicContact CH2-CB 3.97Å; W360-P408 HydrophobicContact CZ2-CB 3.37Å; W406-P408 WeakPolarHBondContact O-CD 3.49Å
409K96.8Very high98.3Very high177 Ų17741.6 Ų41.677%0.7722%0.22SC*.EExtended strand (participates in β ladder)trans-105.3-19.7-178-63-178-179-1790112.9D407D407-K409 PolarHBondContact O-N 2.87Å; D407-K409 PolarHBondContact OD1-N 2.9Å
410A97.2Very high98.3Very high25 Ų2543.5 Ų43.521%0.20723%0.229CC..EExtended strand (participates in β ladder)trans-64.1146.9171.900000110.2D407 H434 G435 V436D407-A410 HydrophobicContact CB-CB 3.66Å; D407-A410 PolarHBondContact OD1-N 2.84Å; D407-A410 VanDerWaalsContact OD1-N 3.1Å; A410-H434 CarbonylContact O-C 3.58Å; A410-H434 WeakPolarHBondContact O-CA 3.17Å; A410-G435 PolarHBondContact O-N 3.08Å; A410-V436 HydrophobicContact CB-CB 4.03Å; A410-V436 HydrophobicContact CB-CG2 4.07Å
411T97.8Very high98.3Very high86 Ų8642.9 Ų42.953%0.52823%0.225SC..EExtended strand (participates in β ladder)trans-122.5140.3179.855.10000110.3C433 H434T411-C433 CarbonylContact C-O 3.48Å; T411-C433 VanDerWaalsContact CA-O 3.29Å; T411-C433 WeakPolarHBondContact CA-O 3.49Å; T411-H434 VanDerWaalsContact CG2-CD2 3.44Å; T411-H434 WeakPolarHBondContact CG2-CD2 3.19Å
412R97.4Very high98.3Very high50 Ų5044.8 Ų44.819%0.18924%0.241CC..EExtended strand (participates in β ladder)trans-130.7146.9167.571.6-179.8-176.9112.54.7110.7D354 S357 V432 C433 V436D354-R412 IonicContact OD1-CZ 3.67Å; D354-R412 VanDerWaalsContact OD1-CZ 3.31Å; D354-R412 IonicContact OD1-NH1 3.45Å; D354-R412 PolarHBondContact OD1-NH1 2.94Å; D354-R412 IonicContact OD1-NH2 3.18Å; D354-R412 PolarHBondContact OD1-NH2 2.63Å; S357-R412 PolarHBondContact OG-NE 2.99Å; S357-R412 VanDerWaalsContact OG-NE 3.13Å; S357-R412 PolarHBondContact OG-NH2 2.79Å; R412-V432 WeakPolarHBondContact O-CA 3.45Å; R412-C433 PolarHBondContact N-O 2.63Å; R412-C433 PolarHBondContact O-N 3.22Å; R412-V436 HydrophobicContact CB-CG2 3.97Å; R412-V436 HydrophobicContact CG-CG2 3.9Å
413T98.7Very high98.3Very high82 Ų8244.3 Ų44.350%0.50324%0.238SC..EExtended strand (participates in β ladder)trans-97120.9166.4-55.90000108S415 M431T413-S415 PolarHBondContact O-N 2.6Å; T413-M431 WeakPolarHBondContact CA-O 3.05Å
414I98.8Very high98.3Very high0 Ų048.6 Ų48.60%026%0.261CS..  trans-68.3130.6178.5-62.7172.7000109.1D354 V358 N426 F428 G430 M431D354-I414 HydrophobicContact CB-CD1 4.02Å; V358-I414 HydrophobicContact CG2-CD1 3.88Å; I414-N426 HydrophobicContact CG2-CB 4.47Å; I414-N426 VanDerWaalsContact CG2-ND2 3.26Å; I414-N426 WeakPolarHBondContact CG2-ND2 3.14Å; I414-F428 HydrophobicContact CB-CB 4.41Å; I414-F428 HydrophobicContact CD1-CB 3.89Å; I414-F428 HydrophobicContact CG2-CB 4.04Å; I414-G430 PolarHBondContact O-N 2.92Å; I414-M431 HydrophobicContact CD1-CB 4.36Å; I414-M431 PolarHBondContact N-O 2.58Å
415S98.6Very high98.3Very high17 Ų1749.1 Ų49.112%0.11926%0.264CS..  trans-149.9141.7174.9-1750000111.7T413 K417 T418 H419 E429T413-S415 PolarHBondContact O-N 2.6Å; S415-K417 PolarHBondContact O-N 3.44Å; S415-K417 VanDerWaalsContact O-N 3.13Å; S415-K417 PolarHBondContact OG-N 3.23Å; S415-T418 PolarHBondContact O-N 2.86Å; S415-T418 PolarHBondContact O-OG1 3.44Å; S415-H419 PolarHBondContact O-N 2.84Å; S415-E429 WeakPolarHBondContact CA-OE1 3.45Å; S415-E429 VanDerWaalsContact CA-OE2 3.29Å; S415-E429 WeakPolarHBondContact CA-OE2 3.12Å; S415-E429 VanDerWaalsContact CB-OE1 3.29Å; S415-E429 WeakPolarHBondContact CB-OE1 3.27Å; S415-E429 PolarHBondContact OG-OE1 2.92Å
416A98.5Very high98.3Very high25 Ų2549.4 Ų49.421%0.20727%0.265CS..THydrogen-bonded Turntrans-58.5-20.6169.900000112.8T418 H419 N426 E429A416-T418 VanDerWaalsContact C-N 3.3Å; A416-H419 PolarHBondContact O-CD2 2.81Å; A416-H419 PolarHBondContact O-NE2 2.84Å; A416-H419 VanDerWaalsContact O-NE2 3.16Å; A416-N426 HydrophobicContact CB-CB 4.26Å; A416-E429 PolarHBondContact N-OE2 3.06Å
417K98.4Very high98.3Very high192 Ų19249.8 Ų49.884%0.83527%0.267SS*.THydrogen-bonded Turntrans-74.3-21.6176.1-65.3-179.8-178.2174.40113.5S415S415-K417 PolarHBondContact O-N 3.44Å; S415-K417 VanDerWaalsContact O-N 3.13Å; S415-K417 PolarHBondContact OG-N 3.23Å
418T98.1Very high98.3Very high90 Ų9048.7 Ų48.755%0.55226%0.261SS*.THydrogen-bonded Turntrans-123.2-10.5-171.657.60000113.4S415 A416S415-T418 PolarHBondContact O-N 2.86Å; S415-T418 PolarHBondContact O-OG1 3.44Å; A416-T418 VanDerWaalsContact C-N 3.3Å
419H98.4Very high98.3Very high26 Ų2652 Ų5212%0.1227%0.273CS..  trans-70168173.775173.2000111.4E353 S415 A416 Q421 V423 F425E353-H419 WeakPolarHBondContact OE1-CA 3.39Å; S415-H419 PolarHBondContact O-N 2.84Å; A416-H419 PolarHBondContact O-CD2 2.81Å; A416-H419 PolarHBondContact O-NE2 2.84Å; A416-H419 VanDerWaalsContact O-NE2 3.16Å; H419-Q421 PolarHBondContact ND1-NE2 2.87Å; H419-V423 PolarHBondContact CE1-O 3.35Å; H419-V423 PolarHBondContact NE2-O 3.46Å; H419-F425 PolarHBondContact CE1-O 2.94Å
420H98.5Very high98.4Very high43 Ų4345.7 Ų45.720%0.19926%0.259CS..  trans-113.818.8-179.6-50.685.7000111.2Q85 A89 E353 F453Q85-H420 PolarHBondContact NE2-O 3.3Å; A89-H420 HydrophobicContact CB-CB 4.48Å; A89-H420 WeakPolarHBondContact CB-O 3.39Å; E353-H420 IonicContact OE1-CE1 3.97Å; E353-H420 IonicContact OE1-CG 3.54Å; E353-H420 PolarHBondContact OE1-N 2.98Å; E353-H420 IonicContact OE1-ND1 2.78Å; E353-H420 PolarHBondContact OE1-ND1 2.78Å; E353-H420 WeakPolarHBondContact OE2-CA 3.3Å; E353-H420 WeakPolarHBondContact OE2-CB 3.27Å; E353-H420 IonicContact OE2-CG 3.53Å; E353-H420 PolarHBondContact OE2-N 2.88Å; E353-H420 IonicContact OE2-ND1 3.22Å; H420-F453 HydrophobicContact CB-CZ 4.17Å; H420-F453 AromaticContact CD2-CE2 3.42Å; H420-F453 VanDerWaalsContact CD2-CE2 3.42Å; H420-F453 WeakPolarHBondContact CD2-CE2 3.49Å; H420-F453 AromaticContact CD2-CZ 3.77Å; H420-F453 AromaticContact CG-CZ 3.9Å; H420-F453 AromaticContact NE2-CE2 3.91Å
421Q98.3Very high98.5Very high11 Ų1145.9 Ų45.95%0.05126%0.256CS..SBendtrans-85.8155.4171-64.1161.495.100109D81 A89 N327 N350 G351 V352 E353 D354 H419 V423D81-Q421 WeakPolarHBondContact OD1-CA 3.31Å; A89-Q421 HydrophobicContact CB-CG 3.64Å; N327-Q421 PolarHBondContact OD1-OE1 3.35Å; N350-Q421 VanDerWaalsContact CB-OE1 3.27Å; G351-Q421 VanDerWaalsContact N-OE1 3.16Å; V352-Q421 HydrophobicContact CG1-CG 4.25Å; E353-Q421 HydrophobicContact CB-CG 4.27Å; D354-Q421 PolarHBondContact OD2-NE2 3.22Å; H419-Q421 PolarHBondContact ND1-NE2 2.87Å; Q421-V423 VanDerWaalsContact C-N 3.3Å; Q421-V423 HydrophobicContact CB-CG1 4.07Å
422A98.4Very high98.5Very high40 Ų4045.3 Ų45.333%0.33125%0.252SS..SBendtrans-75.7-20.317900000113.2I80 D81 Q85I80-A422 HydrophobicContact CB-CB 4.44Å; I80-A422 HydrophobicContact CG1-CB 3.91Å; I80-A422 HydrophobicContact CG2-CB 4.07Å; D81-A422 WeakPolarHBondContact OD1-CB 3.29Å; D81-A422 PolarHBondContact OD1-N 2.85Å; Q85-A422 HydrophobicContact CG-CB 4Å
423V98.6Very high98.6Very high1 Ų142.9 Ų42.91%0.00624%0.243CC..SBendtrans-73.1139.7-174.964.90000112.3I80 T329 N331 N350 H419 Q421 F425I80-V423 HydrophobicContact CG2-CB 3.9Å; I80-V423 HydrophobicContact CG2-CG2 4.45Å; T329-V423 HydrophobicContact CG2-CB 4.18Å; T329-V423 HydrophobicContact CG2-CG1 3.91Å; N331-V423 WeakPolarHBondContact OD1-CA 3.15Å; N350-V423 HydrophobicContact CB-CG1 3.93Å; H419-V423 PolarHBondContact CE1-O 3.35Å; H419-V423 PolarHBondContact NE2-O 3.46Å; Q421-V423 VanDerWaalsContact C-N 3.3Å; Q421-V423 HydrophobicContact CB-CG1 4.07Å; V423-F425 VanDerWaalsContact C-N 3.26Å; V423-F425 WeakPolarHBondContact CG1-O 3.48Å; V423-F425 HydrophobicContact CG2-CD1 3.69Å; V423-F425 HydrophobicContact CG2-CE1 3.48Å; V423-F425 VanDerWaalsContact CG2-CE1 3.48Å; V423-F425 HydrophobicContact CG2-CE2 4.34Å; V423-F425 HydrophobicContact CG2-CG 4.25Å; V423-F425 HydrophobicContact CG2-CZ 3.81Å; V423-F425 PolarHBondContact O-N 3.36Å
424N98.3Very high98.6Very high91 Ų9141.4 Ų41.449%0.48723%0.23SC..SBendtrans-84.919.8-172.871.2-6.3000116.1N331 T332N331-N424 PolarHBondContact OD1-N 2.8Å; N331-N424 PolarHBondContact OD1-OD1 3.13Å; T332-N424 PolarHBondContact N-OD1 3.16Å; T332-N424 PolarHBondContact OG1-OD1 2.89Å
425F98.7Very high98.5Very high12 Ų1241.4 Ų41.45%0.05323%0.23CC..  trans-150.2171.5174.864.9-98.2000110.4H294 F330 H419 V423 I427H294-F425 HydrophobicContact CB-CD1 4.35Å; H294-F425 HydrophobicContact CB-CD2 3.64Å; H294-F425 HydrophobicContact CB-CE1 4.24Å; H294-F425 HydrophobicContact CB-CE2 3.56Å; H294-F425 HydrophobicContact CB-CG 4.06Å; H294-F425 HydrophobicContact CB-CZ 3.88Å; H294-F425 AromaticContact CD2-CD1 3.28Å; H294-F425 WeakPolarHBondContact CD2-CD1 3.17Å; H294-F425 AromaticContact CD2-CE1 3.34Å; H294-F425 WeakPolarHBondContact CD2-CE1 3.13Å; H294-F425 AromaticContact CD2-CG 3.7Å; H294-F425 AromaticContact CD2-CZ 3.87Å; H294-F425 AromaticContact CE1-CD1 3.76Å; H294-F425 AromaticContact CE1-CG 3.72Å; H294-F425 AromaticContact CG-CD1 3.64Å; H294-F425 AromaticContact CG-CD2 3.67Å; H294-F425 AromaticContact CG-CE1 3.84Å; H294-F425 AromaticContact CG-CE2 3.92Å; H294-F425 AromaticContact CG-CG 3.53Å; H294-F425 AromaticContact ND1-CD1 3.94Å; H294-F425 AromaticContact ND1-CD2 3.95Å; H294-F425 AromaticContact ND1-CG 3.57Å; H294-F425 AromaticContact NE2-CD1 3.37Å; H294-F425 WeakPolarHBondContact NE2-CD1 3.11Å; H294-F425 AromaticContact NE2-CE1 3.88Å; H294-F425 AromaticContact NE2-CG 3.81Å; H294-F425 WeakPolarHBondContact O-CE2 3.26Å; F330-F425 WeakPolarHBondContact O-CE1 3.4Å; H419-F425 PolarHBondContact CE1-O 2.94Å; V423-F425 VanDerWaalsContact C-N 3.26Å; V423-F425 WeakPolarHBondContact CG1-O 3.48Å; V423-F425 HydrophobicContact CG2-CD1 3.69Å; V423-F425 HydrophobicContact CG2-CE1 3.48Å; V423-F425 VanDerWaalsContact CG2-CE1 3.48Å; V423-F425 HydrophobicContact CG2-CE2 4.34Å; V423-F425 HydrophobicContact CG2-CG 4.25Å; V423-F425 HydrophobicContact CG2-CZ 3.81Å; V423-F425 PolarHBondContact O-N 3.36Å; F425-I427 HydrophobicContact CD2-CG2 4.44Å; F425-I427 HydrophobicContact CE2-CG2 4.1Å
426N98.8Very high98.4Very high9 Ų941.8 Ų41.85%0.04823%0.232CC..  trans-139.9128.8171.7-163.7-44000110.1N350 D354 I414 A416 F428 E429N350-N426 PolarHBondContact ND2-ND2 3.19Å; N350-N426 PolarHBondContact ND2-OD1 2.79Å; N350-N426 WeakPolarHBondContact OD1-CA 3.35Å; D354-N426 PolarHBondContact OD2-ND2 3.3Å; I414-N426 HydrophobicContact CG2-CB 4.47Å; I414-N426 VanDerWaalsContact CG2-ND2 3.26Å; I414-N426 WeakPolarHBondContact CG2-ND2 3.14Å; A416-N426 HydrophobicContact CB-CB 4.26Å; N426-F428 PolarHBondContact O-N 3.26Å; N426-F428 WeakPolarHBondContact OD1-CD2 3.37Å; N426-F428 PolarHBondContact OD1-N 3.02Å; N426-E429 WeakPolarHBondContact O-CB 3.38Å; N426-E429 PolarHBondContact O-N 2.88Å; N426-E429 VanDerWaalsContact O-N 3.13Å
427I98.8Very high98.4Very high8 Ų840.9 Ų40.94%0.04122%0.224CC..THydrogen-bonded Turntrans-69.2-11.5178.466163.7000113.2A275 T279 V349 N350 F425A275-I427 HydrophobicContact CB-CD1 3.54Å; T279-I427 HydrophobicContact CG2-CD1 4.05Å; V349-I427 HydrophobicContact CB-CD1 3.96Å; V349-I427 HydrophobicContact CB-CG2 4.07Å; V349-I427 HydrophobicContact CG1-CD1 4.37Å; V349-I427 HydrophobicContact CG1-CG2 4.03Å; V349-I427 HydrophobicContact CG2-CD1 3.85Å; N350-I427 PolarHBondContact OD1-N 3.49Å; F425-I427 HydrophobicContact CD2-CG2 4.44Å; F425-I427 HydrophobicContact CE2-CG2 4.1Å
428F98.9Very high98.4Very high4 Ų434.6 Ų34.62%0.01820%0.199CC..THydrogen-bonded Turntrans-10620.1174.3-46.5-66.5000112.3A274 T279 D354 V358 I414 N426 G430 M431A274-F428 HydrophobicContact CB-CE2 4.43Å; A274-F428 HydrophobicContact CB-CZ 4.01Å; A274-F428 WeakPolarHBondContact O-CZ 3.3Å; T279-F428 HydrophobicContact CG2-CD1 4.49Å; T279-F428 HydrophobicContact CG2-CE1 4.14Å; D354-F428 HydrophobicContact CB-CD2 3.85Å; D354-F428 HydrophobicContact CB-CE2 4.14Å; V358-F428 HydrophobicContact CG1-CE1 4.38Å; V358-F428 HydrophobicContact CG2-CD1 4.2Å; V358-F428 HydrophobicContact CG2-CD2 4.14Å; V358-F428 HydrophobicContact CG2-CE1 4.37Å; V358-F428 HydrophobicContact CG2-CE2 4.31Å; V358-F428 HydrophobicContact CG2-CG 4.08Å; V358-F428 HydrophobicContact CG2-CZ 4.42Å; I414-F428 HydrophobicContact CB-CB 4.41Å; I414-F428 HydrophobicContact CD1-CB 3.89Å; I414-F428 HydrophobicContact CG2-CB 4.04Å; N426-F428 PolarHBondContact O-N 3.26Å; N426-F428 WeakPolarHBondContact OD1-CD2 3.37Å; N426-F428 PolarHBondContact OD1-N 3.02Å; F428-G430 PolarHBondContact O-N 3.05Å; F428-M431 HydrophobicContact CB-CB 4.31Å; F428-M431 HydrophobicContact CB-CE 4.22Å; F428-M431 HydrophobicContact CD1-CE 3.82Å; F428-M431 HydrophobicContact CG-CE 4.42Å; F428-M431 WeakPolarHBondContact O-CB 3.31Å; F428-M431 PolarHBondContact O-N 3.41Å
429E98.7Very high98.4Very high102 Ų10230.9 Ų30.948%0.47718%0.176SC..THydrogen-bonded Turntrans-50.2126.9-178.3-172.368-148.600111.8S415 A416 N426 M431S415-E429 WeakPolarHBondContact CA-OE1 3.45Å; S415-E429 VanDerWaalsContact CA-OE2 3.29Å; S415-E429 WeakPolarHBondContact CA-OE2 3.12Å; S415-E429 VanDerWaalsContact CB-OE1 3.29Å; S415-E429 WeakPolarHBondContact CB-OE1 3.27Å; S415-E429 PolarHBondContact OG-OE1 2.92Å; A416-E429 PolarHBondContact N-OE2 3.06Å; N426-E429 WeakPolarHBondContact O-CB 3.38Å; N426-E429 PolarHBondContact O-N 2.88Å; N426-E429 VanDerWaalsContact O-N 3.13Å; E429-M431 VanDerWaalsContact C-N 3.28Å; E429-M431 PolarHBondContact O-N 2.98Å
430G98.7Very high98.4Very high45 Ų4529.7 Ų29.746%0.46417%0.17SC..THydrogen-bonded Turntrans80.9-3.4179.500000115.1I414 F428 V432I414-G430 PolarHBondContact O-N 2.92Å; F428-G430 PolarHBondContact O-N 3.05Å; G430-V432 PolarHBondContact O-N 3.13Å
431M98.8Very high98.4Very high29 Ų2927.6 Ų27.614%0.14316%0.161CC..  trans-67.3120.9176.5-172.8-177.8-62.200110.5G278 V358 T413 I414 F428 E429G278-M431 WeakPolarHBondContact O-CE 3.22Å; V358-M431 HydrophobicContact CG2-SD 4.08Å; T413-M431 WeakPolarHBondContact CA-O 3.05Å; I414-M431 HydrophobicContact CD1-CB 4.36Å; I414-M431 PolarHBondContact N-O 2.58Å; F428-M431 HydrophobicContact CB-CB 4.31Å; F428-M431 HydrophobicContact CB-CE 4.22Å; F428-M431 HydrophobicContact CD1-CE 3.82Å; F428-M431 HydrophobicContact CG-CE 4.42Å; F428-M431 WeakPolarHBondContact O-CB 3.31Å; F428-M431 PolarHBondContact O-N 3.41Å; E429-M431 VanDerWaalsContact C-N 3.28Å; E429-M431 PolarHBondContact O-N 2.98Å
432V98.8Very high98.4Very high74 Ų7427.3 Ų27.345%0.44816%0.16SC..EExtended strand (participates in β ladder)trans-82.7121.9170.7-177.30000108.1R412 G430R412-V432 WeakPolarHBondContact O-CA 3.45Å; G430-V432 PolarHBondContact O-N 3.13Å
433C98.6Very high98.4Very high0 Ų029.6 Ų29.60%016%0.16CC..EExtended strand (participates in β ladder)trans-118.2130.8176.5-62.30000110.4E361 T411 R412E361-C433 HydrophobicContact CB-CB 4.02Å; E361-C433 HydrophobicContact CG-CB 4.44Å; E361-C433 WeakPolarHBondContact OE2-CA 3.35Å; T411-C433 CarbonylContact C-O 3.48Å; T411-C433 VanDerWaalsContact CA-O 3.29Å; T411-C433 WeakPolarHBondContact CA-O 3.49Å; R412-C433 PolarHBondContact N-O 2.63Å; R412-C433 PolarHBondContact O-N 3.22Å
434H98.5Very high98.3Very high50 Ų5029.5 Ų29.523%0.23116%0.16CC..EExtended strand (participates in β ladder)trans-76.4156.7158.4-58.280.5000109.4W360 E361 H365 A410 T411W360-H434 VanDerWaalsContact CD1-C 3.46Å; E361-H434 IonicContact OE1-ND1 3.52Å; E361-H434 IonicContact OE2-CE1 2.85Å; E361-H434 IonicContact OE2-CG 3.97Å; E361-H434 PolarHBondContact OE2-N 2.9Å; E361-H434 IonicContact OE2-ND1 3.6Å; E361-H434 PolarHBondContact OE2-ND1 3.22Å; H365-H434 HydrophobicContact CB-CB 4.44Å; H365-H434 AromaticContact CD2-CE1 3.88Å; H365-H434 AromaticContact CD2-ND1 3.44Å; H365-H434 PolarHBondContact CD2-ND1 3.3Å; H365-H434 AromaticContact CE1-CD2 3.92Å; H365-H434 AromaticContact CE1-CE1 3.5Å; H365-H434 PolarHBondContact CE1-CE1 3.42Å; H365-H434 VanDerWaalsContact CE1-CE1 3.5Å; H365-H434 AromaticContact CE1-CG 3.76Å; H365-H434 AromaticContact CE1-ND1 3.5Å; H365-H434 PolarHBondContact CE1-ND1 2.91Å; H365-H434 AromaticContact CE1-NE2 3.78Å; H365-H434 AromaticContact CG-CG 3.98Å; H365-H434 AromaticContact CG-ND1 3.7Å; H365-H434 AromaticContact ND1-CG 3.72Å; H365-H434 AromaticContact ND1-ND1 3.73Å; H365-H434 AromaticContact NE2-CE1 3.3Å; H365-H434 PolarHBondContact NE2-CE1 2.92Å; H365-H434 VanDerWaalsContact NE2-CE1 3.3Å; H365-H434 AromaticContact NE2-ND1 3.34Å; H365-H434 PolarHBondContact NE2-ND1 3.48Å; A410-H434 CarbonylContact O-C 3.58Å; A410-H434 WeakPolarHBondContact O-CA 3.17Å; T411-H434 VanDerWaalsContact CG2-CD2 3.44Å; T411-H434 WeakPolarHBondContact CG2-CD2 3.19Å
435G97.1Very high98.3Very high0 Ų030 Ų300%016%0.158CC..EExtended strand (participates in β ladder)trans80.8102.7-178.500000111.6S357 W406 D407 A410S357-G435 PolarHBondContact OG-O 2.88Å; W406-G435 VanDerWaalsContact CE2-C 3.46Å; W406-G435 VanDerWaalsContact CE2-CA 3.42Å; W406-G435 VanDerWaalsContact CH2-O 3.27Å; W406-G435 WeakPolarHBondContact CH2-O 3.46Å; W406-G435 WeakPolarHBondContact CZ2-O 3.45Å; D407-G435 VanDerWaalsContact O-CA 3.23Å; D407-G435 WeakPolarHBondContact O-CA 3.13Å; A410-G435 PolarHBondContact O-N 3.08Å
436V96.8Very high98.2Very high25 Ų2530 Ų3015%0.15216%0.158CC..EExtended strand (participates in β ladder)trans-129.4135.5-177.8-177.70000109.7D407 A410 R412 L438D407-V436 PolarHBondContact N-O 2.79Å; D407-V436 PolarHBondContact O-N 2.81Å; A410-V436 HydrophobicContact CB-CB 4.03Å; A410-V436 HydrophobicContact CB-CG2 4.07Å; R412-V436 HydrophobicContact CB-CG2 3.97Å; R412-V436 HydrophobicContact CG-CG2 3.9Å; V436-L438 PolarHBondContact O-N 3.37Å
437P97.9Very high98.2Very high7 Ų729.8 Ų29.85%0.04516%0.158CC..EExtended strand (participates in β ladder)trans-68.3117170.229.6-33.8000109.5A92 V404 W406A92-P437 WeakPolarHBondContact O-CG 3.23Å; V404-P437 HydrophobicContact CG1-CB 3.82Å; W406-P437 HydrophobicContact CE3-CB 4.14Å; W406-P437 HydrophobicContact CZ3-CB 4.21Å; W406-P437 HydrophobicContact CZ3-CG 4.28Å
438L97.9Very high98.2Very high60 Ų6030.8 Ų30.831%0.31416%0.161SC..EExtended strand (participates in β ladder)trans-83.8-42.3174.5-65-174.8000111.5K57 I405 D407 V436K57-L438 HydrophobicContact CD-CD1 3.78Å; K57-L438 HydrophobicContact CG-CD1 4.24Å; I405-L438 PolarHBondContact O-N 3.22Å; D407-L438 HydrophobicContact CB-CD1 3.77Å; D407-L438 HydrophobicContact CB-CD2 4.03Å; D407-L438 HydrophobicContact CB-CG 3.75Å; V436-L438 PolarHBondContact O-N 3.37Å
439V98.8Very high98.1Very high12 Ų1234 Ų347%0.07318%0.176CC..EExtended strand (participates in β ladder)trans-138.1130.1-179.2-170.50000108.7L52 V404 I405 I441 V446 Y448 E449L52-V439 HydrophobicContact CD1-CG1 4.32Å; V404-V439 WeakPolarHBondContact CA-O 3.43Å; I405-V439 HydrophobicContact CB-CB 4.01Å; I405-V439 HydrophobicContact CB-CG2 4.31Å; I405-V439 HydrophobicContact CD1-CB 4.02Å; I405-V439 HydrophobicContact CD1-CG2 4.08Å; I405-V439 HydrophobicContact CG1-CB 4.15Å; I405-V439 PolarHBondContact N-O 2.88Å; I405-V439 PolarHBondContact O-N 3.27Å; V439-I441 HydrophobicContact CG1-CG1 4.19Å; V439-V446 HydrophobicContact CG1-CG1 3.71Å; V439-V446 HydrophobicContact CG1-CG2 4.21Å; V439-Y448 CarbonylContact C-O 3.6Å; V439-Y448 VanDerWaalsContact CA-O 3.31Å; V439-Y448 WeakPolarHBondContact CA-O 3.39Å; V439-E449 HydrophobicContact CG1-CB 4.43Å; V439-E449 HydrophobicContact CG2-CB 4.5Å; V439-E449 HydrophobicContact CG2-CG 4.11Å
440T98.9Very high97.6Very high0 Ų033.6 Ų33.60%019%0.19CC..EExtended strand (participates in β ladder)trans-112128.3169.8-54.40000109.1L91 T96 V404 V447 Y448L91-T440 HydrophobicContact CB-CG2 4.48Å; L91-T440 HydrophobicContact CD2-CG2 3.76Å; L91-T440 VanDerWaalsContact O-CB 3.31Å; L91-T440 WeakPolarHBondContact O-CB 3.05Å; L91-T440 WeakPolarHBondContact O-CG2 3.42Å; L91-T440 PolarHBondContact O-OG1 2.92Å; T96-T440 HydrophobicContact CG2-CG2 3.63Å; V404-T440 HydrophobicContact CG2-CG2 4.29Å; T440-V447 HydrophobicContact CG2-CG2 4.17Å; T440-V447 VanDerWaalsContact O-CG2 3.25Å; T440-V447 WeakPolarHBondContact O-CG2 3.26Å; T440-V447 PolarHBondContact O-N 3.43Å; T440-Y448 PolarHBondContact N-O 3.07Å; T440-Y448 PolarHBondContact O-N 2.96Å
441I98.8Very high97.2Very high0 Ų033.5 Ų33.50%019%0.189CC..EExtended strand (participates in β ladder)trans-113.6125.3178.4-56166.5000106.9L7 I9 L52 A401 D402 I403 V439 K445 V446L7-I441 HydrophobicContact CD1-CD1 4.47Å; L7-I441 HydrophobicContact CD1-CG2 3.94Å; I9-I441 HydrophobicContact CD1-CD1 3.54Å; I9-I441 HydrophobicContact CG1-CD1 4.04Å; L52-I441 HydrophobicContact CD1-CD1 3.7Å; L52-I441 HydrophobicContact CD1-CG1 4.39Å; A401-I441 WeakPolarHBondContact O-CG2 3.36Å; D402-I441 CarbonylContact C-O 3.57Å; D402-I441 VanDerWaalsContact CA-O 3.32Å; D402-I441 WeakPolarHBondContact CA-O 3.32Å; I403-I441 HydrophobicContact CB-CB 4.32Å; I403-I441 HydrophobicContact CB-CD1 4.34Å; I403-I441 PolarHBondContact N-O 3.21Å; I403-I441 WeakPolarHBondContact O-CA 3.2Å; I403-I441 WeakPolarHBondContact O-CB 3.36Å; I403-I441 PolarHBondContact O-N 3.21Å; V439-I441 HydrophobicContact CG1-CG1 4.19Å; I441-K445 CarbonylContact C-O 3.46Å; I441-K445 VanDerWaalsContact CA-O 3.23Å; I441-K445 WeakPolarHBondContact CA-O 3.42Å; I441-K445 WeakPolarHBondContact CG2-O 3.32Å; I441-V446 HydrophobicContact CG1-CG2 4.19Å
442S98.6Very high97.1Very high5 Ų536.5 Ų36.54%0.03521%0.209CC..EExtended strand (participates in β ladder)trans-125.8128.1177.1175.60000108G444 K445S442-G444 PolarHBondContact O-N 3.26Å; S442-G444 VanDerWaalsContact O-N 3.13Å; S442-K445 PolarHBondContact N-O 2.84Å; S442-K445 PolarHBondContact O-N 2.7Å
443R97.5Very high97Very high87 Ų8735.2 Ų35.233%0.32820%0.197SC..THydrogen-bonded Turntrans51.736.9-177.8-48.5-178.863.168.813.9112.6G30 D128 A401 D402 K445G30-R443 VanDerWaalsContact CA-O 3.25Å; G30-R443 WeakPolarHBondContact CA-O 3.45Å; D128-R443 VanDerWaalsContact CG-NH1 3.31Å; D128-R443 WeakPolarHBondContact OD1-CD 3.43Å; D128-R443 IonicContact OD1-CZ 2.73Å; D128-R443 IonicContact OD1-NE 2.8Å; D128-R443 IonicContact OD1-NH1 3.05Å; D128-R443 PolarHBondContact OD1-NH1 2.84Å; D128-R443 IonicContact OD2-NH1 4Å; D128-R443 PolarHBondContact OD2-NH1 3.12Å; A401-R443 PolarHBondContact O-N 2.94Å; D402-R443 PolarHBondContact OD1-N 3.39Å; R443-K445 VanDerWaalsContact C-N 3.31Å; R443-K445 PolarHBondContact O-N 3.31Å
444G97.1Very high97Very high0 Ų039 Ų390%022%0.224CC..THydrogen-bonded Turntrans66.823.1-178.700000115.8S5 L7 A401 S442S5-G444 PolarHBondContact OG-O 2.87Å; L7-G444 WeakPolarHBondContact CD1-O 3.4Å; A401-G444 PolarHBondContact O-N 3.23Å; S442-G444 PolarHBondContact O-N 3.26Å; S442-G444 VanDerWaalsContact O-N 3.13Å
445K97.1Very high96.8Very high102 Ų10237.7 Ų37.744%0.44322%0.219SC..EExtended strand (participates in β ladder)trans-117.6136.5170.1-60.4178.9-175.61760109.3I441 S442 R443 V447 D459I441-K445 CarbonylContact C-O 3.46Å; I441-K445 VanDerWaalsContact CA-O 3.23Å; I441-K445 WeakPolarHBondContact CA-O 3.42Å; I441-K445 WeakPolarHBondContact CG2-O 3.32Å; S442-K445 PolarHBondContact N-O 2.84Å; S442-K445 PolarHBondContact O-N 2.7Å; R443-K445 VanDerWaalsContact C-N 3.31Å; R443-K445 PolarHBondContact O-N 3.31Å; K445-V447 HydrophobicContact CB-CG1 4.34Å; K445-V447 PolarHBondContact O-N 3.16Å; K445-D459 IonicContact NZ-OD1 2.78Å
446V98Very high96.7Very high11 Ų1142.3 Ų42.37%0.06725%0.248CC..EExtended strand (participates in β ladder)trans-68.7112.6168.6176.70000107.8L7 L52 V439 I441 E449 S454L7-V446 HydrophobicContact CD1-CG2 4.09Å; L7-V446 HydrophobicContact CD2-CG2 4.47Å; L52-V446 HydrophobicContact CD1-CG2 3.75Å; L52-V446 HydrophobicContact CD2-CG2 4.26Å; V439-V446 HydrophobicContact CG1-CG1 3.71Å; V439-V446 HydrophobicContact CG1-CG2 4.21Å; I441-V446 HydrophobicContact CG1-CG2 4.19Å; V446-E449 HydrophobicContact CG1-CB 3.89Å; V446-S454 WeakPolarHBondContact O-CB 3.49Å
447V98.4Very high96.8Very high5 Ų543.3 Ų43.33%0.0326%0.258CS..EExtended strand (participates in β ladder)trans-108.2-19.9-175.1-70.90000112.9L91 T440 K445 F453 S454 V455L91-V447 HydrophobicContact CB-CG2 4.48Å; L91-V447 HydrophobicContact CD1-CB 4.14Å; L91-V447 HydrophobicContact CD1-CG2 3.85Å; L91-V447 HydrophobicContact CD2-CG2 3.65Å; L91-V447 HydrophobicContact CG-CG2 4.21Å; T440-V447 HydrophobicContact CG2-CG2 4.17Å; T440-V447 VanDerWaalsContact O-CG2 3.25Å; T440-V447 WeakPolarHBondContact O-CG2 3.26Å; T440-V447 PolarHBondContact O-N 3.43Å; K445-V447 HydrophobicContact CB-CG1 4.34Å; K445-V447 PolarHBondContact O-N 3.16Å; V447-F453 CarbonylContact O-C 3.56Å; V447-F453 WeakPolarHBondContact O-CA 3.39Å; V447-S454 PolarHBondContact O-N 3.02Å; V447-V455 HydrophobicContact CB-CB 3.98Å; V447-V455 HydrophobicContact CB-CG2 4.42Å; V447-V455 HydrophobicContact CG1-CB 3.92Å; V447-V455 HydrophobicContact CG1-CG2 3.98Å
448Y98.5Very high96.8Very high29 Ų2943.7 Ų43.711%0.11426%0.263CS..EExtended strand (participates in β ladder)trans-144.1129173.4-179.5-102.7000109.3A92 V439 T440 V452 F453A92-Y448 HydrophobicContact CB-CD2 4.14Å; A92-Y448 HydrophobicContact CB-CE1 4.4Å; A92-Y448 HydrophobicContact CB-CE2 3.85Å; V439-Y448 CarbonylContact C-O 3.6Å; V439-Y448 VanDerWaalsContact CA-O 3.31Å; V439-Y448 WeakPolarHBondContact CA-O 3.39Å; T440-Y448 PolarHBondContact N-O 3.07Å; T440-Y448 PolarHBondContact O-N 2.96Å; Y448-V452 WeakPolarHBondContact CA-O 3.33Å; Y448-F453 AromaticContact CD2-CD1 3.97Å; Y448-F453 HydrophobicContact CD2-CD1 3.97Å; Y448-F453 HydrophobicContact CD2-CD2 4.46Å; Y448-F453 AromaticContact CD2-CE1 3.76Å; Y448-F453 HydrophobicContact CD2-CE1 3.76Å; Y448-F453 HydrophobicContact CD2-CE2 4.29Å; Y448-F453 HydrophobicContact CD2-CG 4.33Å; Y448-F453 AromaticContact CD2-CZ 3.96Å; Y448-F453 HydrophobicContact CD2-CZ 3.96Å; Y448-F453 HydrophobicContact CE2-CE1 4.38Å; Y448-F453 HydrophobicContact CE2-CE2 4.27Å; Y448-F453 HydrophobicContact CE2-CZ 4.12Å
449E97.3Very high96.7Very high72 Ų7243.2 Ų43.234%0.33626%0.261SS..EExtended strand (participates in β ladder)trans-154.7131.4176.2176.7178.3-116.200109R50 V439 V446 G451 V452R50-E449 IonicContact CZ-OE2 2.83Å; R50-E449 IonicContact NH2-OE1 2.77Å; R50-E449 PolarHBondContact NH2-OE1 3.17Å; R50-E449 IonicContact NH2-OE2 2.68Å; R50-E449 PolarHBondContact NH2-OE2 2.94Å; V439-E449 HydrophobicContact CG1-CB 4.43Å; V439-E449 HydrophobicContact CG2-CB 4.5Å; V439-E449 HydrophobicContact CG2-CG 4.11Å; V446-E449 HydrophobicContact CG1-CB 3.89Å; E449-G451 PolarHBondContact O-N 2.99Å; E449-G451 VanDerWaalsContact O-N 3.14Å; E449-V452 PolarHBondContact N-O 3.38Å; E449-V452 VanDerWaalsContact N-O 3.08Å; E449-V452 WeakPolarHBondContact O-CB 3.36Å; E449-V452 PolarHBondContact O-N 3.31Å
450A88.7Confident96.7Very high93 Ų9342.8 Ų42.877%0.76926%0.259SS*.THydrogen-bonded Turntrans50.639.4176.200000114.4V452A450-V452 VanDerWaalsContact C-N 3.28Å; A450-V452 PolarHBondContact O-N 3.42Å
451G89.9Confident96.7Very high43 Ų4347.5 Ų47.544%0.44328%0.279SS..THydrogen-bonded Turntrans80.11.6-179.100000115.2E449E449-G451 PolarHBondContact O-N 2.99Å; E449-G451 VanDerWaalsContact O-N 3.14Å
452V96.4Very high96.7Very high92 Ų9248.9 Ų48.956%0.55829%0.286SS*.EExtended strand (participates in β ladder)trans-107.9129.3-177.2-176.80000110.6Y448 E449 A450Y448-V452 WeakPolarHBondContact CA-O 3.33Å; E449-V452 PolarHBondContact N-O 3.38Å; E449-V452 VanDerWaalsContact N-O 3.08Å; E449-V452 WeakPolarHBondContact O-CB 3.36Å; E449-V452 PolarHBondContact O-N 3.31Å; A450-V452 VanDerWaalsContact C-N 3.28Å; A450-V452 PolarHBondContact O-N 3.42Å
453F97.4Very high96.7Very high46 Ų4648.8 Ų48.820%0.20229%0.285CS..EExtended strand (participates in β ladder)trans-86.4134.6172.9-68.8-83.2000111.7K88 A92 H420 V447 Y448 V455K88-F453 HydrophobicContact CB-CD1 4.46Å; K88-F453 HydrophobicContact CB-CE1 3.93Å; K88-F453 HydrophobicContact CB-CZ 4.19Å; K88-F453 HydrophobicContact CG-CD1 4.45Å; K88-F453 HydrophobicContact CG-CE1 4.41Å; K88-F453 VanDerWaalsContact O-CE1 3.23Å; K88-F453 WeakPolarHBondContact O-CE1 3.27Å; A92-F453 HydrophobicContact CB-CE1 4.14Å; A92-F453 HydrophobicContact CB-CZ 3.79Å; H420-F453 HydrophobicContact CB-CZ 4.17Å; H420-F453 AromaticContact CD2-CE2 3.42Å; H420-F453 VanDerWaalsContact CD2-CE2 3.42Å; H420-F453 WeakPolarHBondContact CD2-CE2 3.49Å; H420-F453 AromaticContact CD2-CZ 3.77Å; H420-F453 AromaticContact CG-CZ 3.9Å; H420-F453 AromaticContact NE2-CE2 3.91Å; V447-F453 CarbonylContact O-C 3.56Å; V447-F453 WeakPolarHBondContact O-CA 3.39Å; Y448-F453 AromaticContact CD2-CD1 3.97Å; Y448-F453 HydrophobicContact CD2-CD1 3.97Å; Y448-F453 HydrophobicContact CD2-CD2 4.46Å; Y448-F453 AromaticContact CD2-CE1 3.76Å; Y448-F453 HydrophobicContact CD2-CE1 3.76Å; Y448-F453 HydrophobicContact CD2-CE2 4.29Å; Y448-F453 HydrophobicContact CD2-CG 4.33Å; Y448-F453 AromaticContact CD2-CZ 3.96Å; Y448-F453 HydrophobicContact CD2-CZ 3.96Å; Y448-F453 HydrophobicContact CE2-CE1 4.38Å; Y448-F453 HydrophobicContact CE2-CE2 4.27Å; Y448-F453 HydrophobicContact CE2-CZ 4.12Å; F453-V455 HydrophobicContact CB-CG1 4.43Å; F453-V455 HydrophobicContact CD1-CG1 4.26Å
454S96.7Very high96.8Very high80 Ų8048.3 Ų48.356%0.55929%0.293SS*.  trans-125.452.7172.5-65.60000110.3V446 V447V446-S454 WeakPolarHBondContact O-CB 3.49Å; V447-S454 PolarHBondContact O-N 3.02Å
455V95.7Very high96.8Very high22 Ų2248.4 Ų48.413%0.13329%0.293CS..  trans-139147.1-176.667.40000110.8K88 L91 C126 V447 F453 D459K88-V455 HydrophobicContact CG-CG1 4.4Å; L91-V455 HydrophobicContact CD1-CG1 4.2Å; L91-V455 HydrophobicContact CD1-CG2 4.39Å; C126-V455 HydrophobicContact CB-CB 4.45Å; C126-V455 HydrophobicContact CB-CG1 3.91Å; C126-V455 HydrophobicContact CB-CG2 3.65Å; C126-V455 WeakPolarHBondContact O-CG2 3.34Å; V447-V455 HydrophobicContact CB-CB 3.98Å; V447-V455 HydrophobicContact CB-CG2 4.42Å; V447-V455 HydrophobicContact CG1-CB 3.92Å; V447-V455 HydrophobicContact CG1-CG2 3.98Å; F453-V455 HydrophobicContact CB-CG1 4.43Å; F453-V455 HydrophobicContact CD1-CG1 4.26Å; V455-D459 HydrophobicContact CG2-CB 3.94Å
456T95.3Very high96.9Very high98 Ų9851.2 Ų51.260%0.60131%0.306SS*.  trans-112.3151.9178.1-500000110.3G458 D459T456-G458 PolarHBondContact O-N 3.33Å; T456-D459 PolarHBondContact N-OD2 3.26Å; T456-D459 WeakPolarHBondContact O-CB 3.34Å; T456-D459 PolarHBondContact O-N 3.47Å
457A97.6Very high96.9Very high45 Ų4552.6 Ų52.637%0.37232%0.315SS..THydrogen-bonded Turntrans-54.7132.3171.200000111P123 K124P123-A457 CarbonylContact O-C 3.57Å; K124-A457 WeakPolarHBondContact O-CA 3.28Å
458G97.6Very high96.9Very high15 Ų1556.4 Ų56.416%0.15533%0.331CS..THydrogen-bonded Turntrans82.74.5-179.200000115.2P123 V125 T456 G460 K461P123-G458 PolarHBondContact O-N 3.06Å; V125-G458 CarbonylContact O-C 3.46Å; V125-G458 VanDerWaalsContact O-CA 3.3Å; V125-G458 WeakPolarHBondContact O-CA 3.43Å; V125-G458 PolarHBondContact O-N 3.44Å; T456-G458 PolarHBondContact O-N 3.33Å; G458-G460 VanDerWaalsContact C-N 3.28Å; G458-K461 PolarHBondContact O-NZ 3.45Å
459D97.4Very high96.9Very high51 Ų5155.1 Ų55.127%0.27333%0.326SS..  trans-64-35.4172.1-90.2-31.5000111.9V125 K445 V455 T456V125-D459 PolarHBondContact O-N 2.92Å; K445-D459 IonicContact NZ-OD1 2.78Å; V455-D459 HydrophobicContact CG2-CB 3.94Å; T456-D459 PolarHBondContact N-OD2 3.26Å; T456-D459 WeakPolarHBondContact O-CB 3.34Å; T456-D459 PolarHBondContact O-N 3.47Å
460G98.2Very high97Very high2 Ų259 Ų592%0.02135%0.345CS..SBendtrans-63.8159.5173.500000112.9V125 C127 G458V125-G460 PolarHBondContact O-N 2.86Å; C127-G460 VanDerWaalsContact O-CA 3.27Å; C127-G460 WeakPolarHBondContact O-CA 3.38Å; G458-G460 VanDerWaalsContact C-N 3.28Å
461K98.6Very high97.4Very high99 Ų9959 Ų5943%0.4333%0.325SS..  trans-129.3144.9177.2-58.3-65.2157.1-134.10112.1D128 Y129 G458 I463D128-K461 WeakPolarHBondContact CA-O 3.36Å; D128-K461 PolarHBondContact OD1-N 2.86Å; Y129-K461 PolarHBondContact N-O 3.39Å; G458-K461 PolarHBondContact O-NZ 3.45Å; K461-I463 HydrophobicContact CB-CD1 4.33Å; K461-I463 PolarHBondContact O-N 3.15Å
462F98.9Very high97.8Very high29 Ų2957 Ų5713%0.12730%0.304CS..BIsolated β-bridgetrans-62.8127.1164.9177.3-102.8000109.8F114 Y129 L131 K153 P464F114-F462 HydrophobicContact CE2-CE2 4.06Å; F114-F462 AromaticContact CE2-CZ 3.87Å; F114-F462 HydrophobicContact CE2-CZ 3.87Å; F114-F462 HydrophobicContact CZ-CE1 4.31Å; F114-F462 HydrophobicContact CZ-CE2 4.24Å; F114-F462 AromaticContact CZ-CZ 3.83Å; F114-F462 HydrophobicContact CZ-CZ 3.83Å; Y129-F462 HydrophobicContact CD1-CB 4.41Å; Y129-F462 HydrophobicContact CD2-CD2 4.47Å; Y129-F462 HydrophobicContact CE1-CB 3.72Å; Y129-F462 HydrophobicContact CE1-CD2 4.45Å; Y129-F462 AromaticContact CE2-CD2 3.95Å; Y129-F462 HydrophobicContact CE2-CD2 3.95Å; Y129-F462 AromaticContact CZ-CD2 3.95Å; Y129-F462 CarbonylContact O-C 3.5Å; Y129-F462 WeakPolarHBondContact O-CA 3.45Å; L131-F462 HydrophobicContact CB-CE2 4.36Å; L131-F462 HydrophobicContact CG-CE2 4.23Å; K153-F462 WeakPolarHBondContact O-CE1 3.3Å; K153-F462 WeakPolarHBondContact O-CZ 3.47Å; F462-P464 HydrophobicContact CE1-CB 4.06Å; F462-P464 WeakPolarHBondContact O-CD 3.18Å
463I98.8Very high97.9Very high4 Ų452.9 Ų52.92%0.02128%0.279CS..  trans-106.3106.3179.2-53.7-52000109.3M97 D128 Y129 S130 L388 K461M97-I463 HydrophobicContact CE-CB 4.01Å; M97-I463 HydrophobicContact CE-CG1 4.25Å; D128-I463 HydrophobicContact CB-CD1 4.2Å; D128-I463 HydrophobicContact CB-CG1 3.84Å; D128-I463 WeakPolarHBondContact OD2-CD1 3.48Å; Y129-I463 PolarHBondContact O-N 3.28Å; S130-I463 WeakPolarHBondContact CB-O 3.37Å; S130-I463 PolarHBondContact OG-O 3.45Å; L388-I463 HydrophobicContact CD2-CB 4.46Å; L388-I463 HydrophobicContact CD2-CG2 3.44Å; L388-I463 VanDerWaalsContact CD2-CG2 3.44Å; K461-I463 HydrophobicContact CB-CD1 4.33Å; K461-I463 PolarHBondContact O-N 3.15Å
464P98.6Very high97.9Very high77 Ų7758.4 Ų58.450%0.530%0.303SS..  trans-67.8141.2176.128.1-34.1000110.6F462F462-P464 HydrophobicContact CE1-CB 4.06Å; F462-P464 WeakPolarHBondContact O-CD 3.18Å
465R98.6Very high97.9Very high1 Ų158.9 Ų58.90%0.00429%0.292CS..  trans-116.3122.7-177-49.6-170.3-52.6-86.6-5.2109.6S130 L131 G154 N156 S157 F386 L388S130-R465 PolarHBondContact OG-NH1 3.45Å; L131-R465 VanDerWaalsContact O-CZ 3.3Å; L131-R465 PolarHBondContact O-NH1 2.89Å; L131-R465 PolarHBondContact O-NH2 3.01Å; G154-R465 CarbonylContact C-O 3.43Å; G154-R465 PolarHBondContact O-N 2.68Å; N156-R465 HydrophobicContact CB-CB 4.37Å; N156-R465 WeakPolarHBondContact ND2-CB 3.46Å; N156-R465 PolarHBondContact OD1-NE 3.19Å; N156-R465 PolarHBondContact OD1-NH2 3.46Å; S157-R465 PolarHBondContact OG-NH2 3.26Å; F386-R465 WeakPolarHBondContact O-CB 3.32Å; F386-R465 VanDerWaalsContact O-CD 3.32Å; F386-R465 WeakPolarHBondContact O-CD 3.18Å; L388-R465 HydrophobicContact CD2-CG 3.98Å; L388-R465 HydrophobicContact CG-CG 4.42Å
466K98.5Very high98.1Very high162 Ų16258 Ų5870%0.70429%0.287SS*.  trans-71.2147.1179.9-67.3179.8-179.9179.10110.5N156 N387N156-K466 PolarHBondContact ND2-O 2.89Å; N387-K466 PolarHBondContact ND2-O 3.11Å
467P98.7Very high98.2Very high39 Ų3958.6 Ų58.625%0.25328%0.281SS..SBendtrans-68.5175.817129.5-34.6000112.1V150 I185 G186 N387 A469V150-P467 HydrophobicContact CG1-CB 3.55Å; V150-P467 HydrophobicContact CG1-CG 3.64Å; I185-P467 VanDerWaalsContact O-CB 3.26Å; I185-P467 WeakPolarHBondContact O-CB 3.34Å; G186-P467 CarbonylContact O-C 3.54Å; G186-P467 WeakPolarHBondContact O-CA 3.43Å; N387-P467 PolarHBondContact ND2-O 2.83Å; P467-A469 PolarHBondContact O-N 3.23Å
468F98.6Very high98.2Very high85 Ų8561.4 Ų61.437%0.37329%0.287SS..SBendtrans56.245.2175.8-58.6-78.3000113.7E184 G186 E470 Y473E184-F468 WeakPolarHBondContact O-CZ 3.27Å; G186-F468 VanDerWaalsContact CA-CD1 3.46Å; G186-F468 PolarHBondContact O-N 3.38Å; F468-E470 PolarHBondContact O-N 3.17Å; F468-Y473 HydrophobicContact CB-CG 4.49Å; F468-Y473 AromaticContact CD1-CD1 3.84Å; F468-Y473 HydrophobicContact CD1-CD1 3.84Å; F468-Y473 HydrophobicContact CD1-CE1 4.12Å; F468-Y473 HydrophobicContact CD1-CG 4.15Å; F468-Y473 HydrophobicContact CE1-CD1 4.44Å; F468-Y473 HydrophobicContact CE1-CE1 4.41Å
469A98.5Very high98.2Very high2 Ų264 Ų642%0.01729%0.291CS..  trans-47.7117.4175.800000110.5N387 P467 Y471 I472 Y473N387-A469 HydrophobicContact CB-CB 3.73Å; P467-A469 PolarHBondContact O-N 3.23Å; A469-Y471 PolarHBondContact O-N 2.88Å; A469-I472 HydrophobicContact CB-CD1 4.11Å; A469-I472 PolarHBondContact O-N 3.23Å; A469-Y473 PolarHBondContact O-N 3.45Å
470E97.9Very high98.1Very high155 Ų15564.4 Ų64.472%0.72429%0.294SS*.Hα-helixtrans-59.8-36.9-171.3-68.9-161.9152.300112.3F468 I472 Y473 K474F468-E470 PolarHBondContact O-N 3.17Å; E470-I472 PolarHBondContact O-N 3.42Å; E470-I472 VanDerWaalsContact O-N 3.1Å; E470-Y473 PolarHBondContact O-N 3.44Å; E470-K474 WeakPolarHBondContact O-CB 3.29Å; E470-K474 PolarHBondContact O-N 3.1Å
471Y98.3Very high98Very high91 Ų9171.1 Ų71.136%0.35733%0.325SS..Hα-helixtrans-51.4-33.6175.1-177.4-110.8000113Y269 K384 I385 A469Y269-Y471 AromaticContact CE1-CE1 3.75Å; Y269-Y471 HydrophobicContact CE1-CE1 3.75Å; K384-Y471 HydrophobicContact CB-CD1 3.76Å; K384-Y471 HydrophobicContact CB-CD2 4.02Å; K384-Y471 HydrophobicContact CB-CE1 4.15Å; K384-Y471 HydrophobicContact CB-CE2 4.4Å; K384-Y471 HydrophobicContact CB-CG 3.68Å; K384-Y471 HydrophobicContact CD-CD2 4.08Å; K384-Y471 HydrophobicContact CD-CE2 4.01Å; K384-Y471 HydrophobicContact CG-CD2 4.41Å; I385-Y471 HydrophobicContact CG1-CD1 3.93Å; I385-Y471 HydrophobicContact CG1-CE1 3.73Å; A469-Y471 PolarHBondContact O-N 2.88Å
472I97.7Very high97.9Very high2 Ų270.8 Ų70.81%0.0133%0.331CS..Hα-helixtrans-96.8-53.9179.8-63165000110.6I188 P243 V267 Y269 I385 A469 E470 K474 R475 I476I188-I472 HydrophobicContact CB-CD1 4.33Å; I188-I472 HydrophobicContact CD1-CD1 3.82Å; P243-I472 HydrophobicContact CB-CG2 3.26Å; P243-I472 HydrophobicContact CG-CG2 3.54Å; V267-I472 HydrophobicContact CG1-CG2 4.27Å; Y269-I472 HydrophobicContact CE2-CG1 4.08Å; I385-I472 HydrophobicContact CB-CD1 4.41Å; I385-I472 HydrophobicContact CG2-CD1 4.06Å; I385-I472 WeakPolarHBondContact O-CD1 3.5Å; A469-I472 HydrophobicContact CB-CD1 4.11Å; A469-I472 PolarHBondContact O-N 3.23Å; E470-I472 PolarHBondContact O-N 3.42Å; E470-I472 VanDerWaalsContact O-N 3.1Å; I472-K474 PolarHBondContact O-N 2.88Å; I472-R475 WeakPolarHBondContact O-CG 3.49Å; I472-I476 HydrophobicContact CG2-CD1 3.96Å
473Y98.6Very high97.6Very high6 Ų673.4 Ų73.42%0.02435%0.352CS..Hα-helixtrans-83-14.6-163.6-82.9-91.3000114.5C182 G186 A187 P243 F468 A469 E470 R475 I476 K477C182-Y473 PolarHBondContact O-OH 3.39Å; G186-Y473 VanDerWaalsContact C-CZ 3.43Å; G186-Y473 VanDerWaalsContact CA-CZ 3.47Å; G186-Y473 WeakPolarHBondContact CA-OH 3.49Å; G186-Y473 WeakPolarHBondContact O-CE2 3.41Å; A187-Y473 VanDerWaalsContact C-OH 3.23Å; A187-Y473 PolarHBondContact N-OH 3.16Å; A187-Y473 PolarHBondContact O-OH 2.89Å; P243-Y473 HydrophobicContact CG-CE1 4.49Å; P243-Y473 HydrophobicContact CG-CE2 3.96Å; F468-Y473 HydrophobicContact CB-CG 4.49Å; F468-Y473 AromaticContact CD1-CD1 3.84Å; F468-Y473 HydrophobicContact CD1-CD1 3.84Å; F468-Y473 HydrophobicContact CD1-CE1 4.12Å; F468-Y473 HydrophobicContact CD1-CG 4.15Å; F468-Y473 HydrophobicContact CE1-CD1 4.44Å; F468-Y473 HydrophobicContact CE1-CE1 4.41Å; A469-Y473 PolarHBondContact O-N 3.45Å; E470-Y473 PolarHBondContact O-N 3.44Å; Y473-R475 VanDerWaalsContact C-N 3.33Å; Y473-R475 PolarHBondContact O-N 2.94Å; Y473-I476 HydrophobicContact CD1-CB 4.31Å; Y473-I476 HydrophobicContact CD1-CD1 4.02Å; Y473-I476 HydrophobicContact CD1-CG2 4.37Å; Y473-I476 HydrophobicContact CE1-CD1 4.12Å; Y473-I476 HydrophobicContact CG-CD1 4.36Å; Y473-I476 PolarHBondContact O-N 3.26Å; Y473-K477 WeakPolarHBondContact O-CG 3.23Å; Y473-K477 PolarHBondContact O-N 3Å
474K98Very high97.3Very high162 Ų16277.8 Ų77.870%0.70438%0.379SS*.Hα-helixtrans-58.5-45.4177.9-172.4173.1-177.9176.70111.6E470 I472 Q478E470-K474 WeakPolarHBondContact O-CB 3.29Å; E470-K474 PolarHBondContact O-N 3.1Å; I472-K474 PolarHBondContact O-N 2.88Å; K474-Q478 PolarHBondContact O-N 2.93Å
475R96.9Very high97.1Very high90 Ų9079.9 Ų79.934%0.3439%0.393SS..Hα-helixtrans-72.6-31.5176.259.9176.8171169.8-2.3113.7V267 Y269 I472 Y473 Q478 R479V267-R475 VanDerWaalsContact CG1-NH2 3.33Å; V267-R475 HydrophobicContact CG2-CG 4.24Å; Y269-R475 PolarHBondContact OH-NH2 3.07Å; I472-R475 WeakPolarHBondContact O-CG 3.49Å; Y473-R475 VanDerWaalsContact C-N 3.33Å; Y473-R475 PolarHBondContact O-N 2.94Å; R475-Q478 PolarHBondContact O-N 2.85Å; R475-R479 WeakPolarHBondContact O-CB 3.21Å; R475-R479 PolarHBondContact O-N 3.4Å
476I98.1Very high97Very high2 Ų285.7 Ų85.71%0.0143%0.429CS..Hα-helixtrans-67.2-47.5179.4-60.9-178000110.4N241 P243 V267 I472 Y473 Q478 R479 D480N241-I476 PolarHBondContact ND2-O 2.9Å; N241-I476 WeakPolarHBondContact O-CG2 3.45Å; P243-I476 HydrophobicContact CB-CD1 3.8Å; P243-I476 VanDerWaalsContact CD-CD1 3.46Å; P243-I476 HydrophobicContact CG-CD1 3.61Å; V267-I476 HydrophobicContact CG1-CD1 4.13Å; V267-I476 HydrophobicContact CG1-CG1 4.31Å; V267-I476 HydrophobicContact CG2-CG1 4.29Å; I472-I476 HydrophobicContact CG2-CD1 3.96Å; Y473-I476 HydrophobicContact CD1-CB 4.31Å; Y473-I476 HydrophobicContact CD1-CD1 4.02Å; Y473-I476 HydrophobicContact CD1-CG2 4.37Å; Y473-I476 HydrophobicContact CE1-CD1 4.12Å; Y473-I476 HydrophobicContact CG-CD1 4.36Å; Y473-I476 PolarHBondContact O-N 3.26Å; I476-Q478 VanDerWaalsContact C-N 3.29Å; I476-Q478 PolarHBondContact O-N 3.27Å; I476-R479 PolarHBondContact O-N 2.97Å; I476-R479 VanDerWaalsContact O-N 3.09Å; I476-D480 PolarHBondContact O-N 3.13Å
477K97.5Very high96.9Very high112 Ų11283.6 Ų83.649%0.48743%0.431SS..Hα-helixtrans-57.1-43.7176.6-72.3176.1-179.81800111.5Y473 D480 Q481Y473-K477 WeakPolarHBondContact O-CG 3.23Å; Y473-K477 PolarHBondContact O-N 3Å; K477-D480 PolarHBondContact O-N 2.81Å; K477-Q481 WeakPolarHBondContact O-CG 3.43Å; K477-Q481 PolarHBondContact O-N 3.48Å
478Q98Very high96.8Very high104 Ų10486.2 Ų86.249%0.48645%0.447SS..Hα-helixtrans-63.5-44.3175.5-171.662.74000111.6K474 R475 I476 D480 Q481 T482K474-Q478 PolarHBondContact O-N 2.93Å; R475-Q478 PolarHBondContact O-N 2.85Å; I476-Q478 VanDerWaalsContact C-N 3.29Å; I476-Q478 PolarHBondContact O-N 3.27Å; Q478-D480 VanDerWaalsContact C-N 3.34Å; Q478-D480 PolarHBondContact O-N 2.84Å; Q478-Q481 WeakPolarHBondContact O-CB 3.29Å; Q478-Q481 PolarHBondContact O-N 2.89Å; Q478-Q481 VanDerWaalsContact O-N 3.16Å; Q478-T482 PolarHBondContact O-N 3.42Å; Q478-T482 VanDerWaalsContact O-OG1 3.12Å; Q478-T482 PolarHBondContact O-OG1 3.14Å; Q478-T482 VanDerWaalsContact NE2-CG2 3.25Å; Q478-T482 HydrophobicContact CG-CG2 4.4Å
479R97.3Very high96.7Very high68 Ų6891.3 Ų91.326%0.25747%0.472SS..Hα-helixtrans-61.8-40.8179.5-169.9-176.8-59.7164.4-14.1112.3N241 G265 R475 I476 Q481 T482 C483N241-R479 VanDerWaalsContact OD1-CD 3.28Å; N241-R479 WeakPolarHBondContact OD1-CD 3.46Å; N241-R479 PolarHBondContact OD1-NH1 2.84Å; G265-R479 PolarHBondContact O-NH2 2.83Å; R475-R479 WeakPolarHBondContact O-CB 3.21Å; R475-R479 PolarHBondContact O-N 3.4Å; I476-R479 PolarHBondContact O-N 2.97Å; I476-R479 VanDerWaalsContact O-N 3.09Å; R479-Q481 VanDerWaalsContact C-N 3.25Å; R479-Q481 PolarHBondContact O-N 3.45Å; R479-T482 PolarHBondContact O-N 2.9Å; R479-C483 HydrophobicContact CG-CB 3.99Å; R479-C483 VanDerWaalsContact O-CB 3.25Å; R479-C483 WeakPolarHBondContact O-CB 3.36Å; R479-C483 PolarHBondContact O-N 2.95Å
480D96.2Very high96.6Very high61 Ų61100.6 Ų100.633%0.32651%0.506SS..Hα-helixtrans-58.7-40.1175.9-73.9-20.8000111.3K183 N241 I476 K477 Q478 T484K183-D480 VanDerWaalsContact CE-OD1 3.26Å; K183-D480 WeakPolarHBondContact CE-OD1 3.5Å; K183-D480 VanDerWaalsContact CE-OD2 3.3Å; K183-D480 WeakPolarHBondContact CE-OD2 3.45Å; K183-D480 VanDerWaalsContact NZ-CG 3.28Å; K183-D480 IonicContact NZ-OD1 2.75Å; K183-D480 PolarHBondContact NZ-OD1 3.26Å; K183-D480 IonicContact NZ-OD2 2.86Å; K183-D480 PolarHBondContact NZ-OD2 3.1Å; N241-D480 PolarHBondContact ND2-OD1 2.99Å; I476-D480 PolarHBondContact O-N 3.13Å; K477-D480 PolarHBondContact O-N 2.81Å; Q478-D480 VanDerWaalsContact C-N 3.34Å; Q478-D480 PolarHBondContact O-N 2.84Å; D480-T484 PolarHBondContact O-OG1 3.22Å
481Q95.2Very high96.5Very high143 Ų14397.4 Ų97.467%0.66851%0.507SS*.Hα-helixtrans-69.5-38.9178.2-66.8172.3-6.200112.8K477 Q478 R479K477-Q481 WeakPolarHBondContact O-CG 3.43Å; K477-Q481 PolarHBondContact O-N 3.48Å; Q478-Q481 WeakPolarHBondContact O-CB 3.29Å; Q478-Q481 PolarHBondContact O-N 2.89Å; Q478-Q481 VanDerWaalsContact O-N 3.16Å; R479-Q481 VanDerWaalsContact C-N 3.25Å; R479-Q481 PolarHBondContact O-N 3.45Å
482T96.1Very high96.4Very high92 Ų9298.3 Ų98.356%0.56452%0.524SS*.Hα-helixtrans-96.4-21.3-170.758.30000114.8Q478 R479Q478-T482 PolarHBondContact O-N 3.42Å; Q478-T482 VanDerWaalsContact O-OG1 3.12Å; Q478-T482 PolarHBondContact O-OG1 3.14Å; Q478-T482 VanDerWaalsContact NE2-CG2 3.25Å; Q478-T482 HydrophobicContact CG-CG2 4.4Å; R479-T482 PolarHBondContact O-N 2.9Å
483C94Very high96.4Very high84 Ų84106.3 Ų106.357%0.56856%0.555SS**  trans-113.119.6-172.2-58.50000112.9R479 P485R479-C483 HydrophobicContact CG-CB 3.99Å; R479-C483 VanDerWaalsContact O-CB 3.25Å; R479-C483 WeakPolarHBondContact O-CB 3.36Å; R479-C483 PolarHBondContact O-N 2.95Å; C483-P485 WeakPolarHBondContact O-CD 3.44Å
484T93Very high96.2Very high96 Ų96115.5 Ų115.559%0.58960%0.595SS**  trans-64.7123.1173.2-68.10000109.7D480 T486D480-T484 PolarHBondContact O-OG1 3.22Å; T484-T486 PolarHBondContact O-N 3.03Å
485P94.5Very high96.1Very high121 Ų121109.7 Ų109.779%0.78658%0.581SS**  trans-61.1133.4177.7-24.134.5000112C483C483-P485 WeakPolarHBondContact O-CD 3.44Å
486T95.1Very high95.9Very high123 Ų123114.3 Ų114.376%0.75561%0.606SS**  trans-105.2133.417754.90000110.6T484T484-T486 PolarHBondContact O-N 3.03Å
487P96.1Very high95.7Very high117 Ų117119.8 Ų119.876%0.7664%0.639SS**PPolyproline II helixtrans-66.5144.8172.829.5-33.9000110.2E489P487-E489 PolarHBondContact O-N 3.13Å
488V97.5Very high95.3Very high95 Ų95118.7 Ų118.758%0.57665%0.651SS**PPolyproline II helixtrans-76.7121.3167.1178.40000107.9R490V488-R490 HydrophobicContact CG1-CG 4.13Å; V488-R490 PolarHBondContact O-N 3.25Å
489E96.5Very high94.8Very high192 Ų192120.4 Ų120.490%0.89767%0.669SS**PPolyproline II helixtrans-65.6120.7173.4-65.3-173.8175.600110P487P487-E489 PolarHBondContact O-N 3.13Å
490R96.4Very high94.1Very high196 Ų196124.7 Ų124.774%0.7470%0.696SS**  trans-130.4145.5178.5-64.1-174.1-179.289.4-1.4109.6V488V488-R490 HydrophobicContact CG1-CG 4.13Å; V488-R490 PolarHBondContact O-N 3.25Å
491A96Very high93.1Very high89 Ų89131.4 Ų131.474%0.73672%0.723SS**PPolyproline II helixtrans-59.4143.6165.500000109.6Y493A491-Y493 PolarHBondContact O-N 2.81Å
492P96.3Very high91.7Very high110 Ų110129.3 Ų129.371%0.71472%0.724SS**PPolyproline II helixtrans-54.1135.8174.6-26.634.8000111.3K494P492-K494 PolarHBondContact O-N 3.11Å
493Y96.1Very high90Very high170 Ų170136.6 Ų136.667%0.66774%0.741SS**PPolyproline II helixtrans-62.6124.7176.1174.8-103.1000110.1A491 G495 E496 V497A491-Y493 PolarHBondContact O-N 2.81Å; Y493-G495 VanDerWaalsContact CE1-C 3.41Å; Y493-G495 WeakPolarHBondContact CE1-O 3.29Å; Y493-G495 WeakPolarHBondContact OH-CA 3.48Å; Y493-E496 PolarHBondContact OH-O 3.16Å; Y493-V497 HydrophobicContact CD1-CG2 4.26Å; Y493-V497 HydrophobicContact CE1-CG2 3.76Å
494K96.1Very high88.1Confident198 Ų198138.4 Ų138.486%0.86175%0.749SS**  trans-109.40-178.6-63.8-175.7-179.1179.70114.1P492P492-K494 PolarHBondContact O-N 3.11Å
495G95.4Very high86.2Confident40 Ų40139.7 Ų139.741%0.41276%0.757SS.*SBendtrans-77.3173.6-17900000112.5Y493Y493-G495 VanDerWaalsContact CE1-C 3.41Å; Y493-G495 WeakPolarHBondContact CE1-O 3.29Å; Y493-G495 WeakPolarHBondContact OH-CA 3.48Å
496E92.4Very high84Confident188 Ų188143.6 Ų143.688%0.87976%0.762SS**  trans-66.1147.9174.8-64.1-176.7172.300111.3Y493Y493-E496 PolarHBondContact OH-O 3.16Å
497V93.1Very high81.6Confident116 Ų116146.3 Ų146.370%0.70376%0.763SS**  trans-119.7123.8173.9-178.50000108.1Y493 T499Y493-V497 HydrophobicContact CD1-CG2 4.26Å; Y493-V497 HydrophobicContact CE1-CG2 3.76Å; V497-T499 PolarHBondContact O-N 3.38Å
498A90.4Very high79.1Confident89 Ų89148.7 Ų148.774%0.73677%0.769SS**  trans-61.9132.6178.300000111.2L500A498-L500 PolarHBondContact O-N 2.85Å
499T86.3Confident76.4Confident140 Ų140148.5 Ų148.586%0.85978%0.778SS**  trans-83.4111.7174.5-40.30000109.9V497V497-T499 PolarHBondContact O-N 3.38Å
500L83.6Confident74Confident158 Ų158145.5 Ų145.583%0.82777%0.773SS**  trans-81.3119.5170.9-67.3170.7000109A498 S502A498-L500 PolarHBondContact O-N 2.85Å; L500-S502 PolarHBondContact O-N 3.32Å; L500-S502 VanDerWaalsContact O-N 3.11Å
501K74.4Confident71.6Confident203 Ų203142.8 Ų142.888%0.88378%0.778SS**  trans-63.1113166.4-73.1-176179.1179.40107.5R503K501-R503 PolarHBondContact O-N 3.5Å
502S67.1Low68.8Low99 Ų99147.3 Ų147.369%0.69278%0.783SS**  trans-56.3132.9174.954.40000109.2L500 V504L500-S502 PolarHBondContact O-N 3.32Å; L500-S502 VanDerWaalsContact O-N 3.11Å; S502-V504 VanDerWaalsContact C-N 3.3Å; S502-V504 PolarHBondContact O-N 3.5Å
503R60.4Low66.1Low244 Ų244147.7 Ų147.792%0.92178%0.784SS**  trans-65.1100162.7-83-177.5175.3179.4-0.9106K501 T505K501-R503 PolarHBondContact O-N 3.5Å; R503-T505 PolarHBondContact O-N 3.3Å
504V52.6Low63.6Low122 Ų122151.4 Ų151.474%0.73980%0.797SS**  trans-56.5104.6167.41780000106.7S502 K506S502-V504 VanDerWaalsContact C-N 3.3Å; S502-V504 PolarHBondContact O-N 3.5Å; V504-K506 PolarHBondContact O-N 3.26Å; V504-K506 VanDerWaalsContact O-N 3.12Å
505T53.3Low61Low123 Ų123150.8 Ų150.876%0.75579%0.794SS**  trans-64.6109.8164.336.30000106.8R503 K507R503-T505 PolarHBondContact O-N 3.3Å; T505-K507 VanDerWaalsContact C-N 3.27Å; T505-K507 PolarHBondContact O-N 3.34Å
506K48.2Very low58.2Low204 Ų204157.7 Ų157.789%0.88782%0.816SS**SBendtrans-56.788.2169.4-81.8-179.2172.1179.50109.3V504V504-K506 PolarHBondContact O-N 3.26Å; V504-K506 VanDerWaalsContact O-N 3.12Å
507K45.6Very low55.9Low180 Ų180153.6 Ų153.678%0.78381%0.814SS**  trans-139.5-6.3164.5-107.2-171.6178.2-174.90115.9T505T505-K507 VanDerWaalsContact C-N 3.27Å; T505-K507 PolarHBondContact O-N 3.34Å
508D43.1Very low53.1Low166 Ų166156.6 Ų156.689%0.88882%0.82SS**SBendtrans-115.231.3179.9-63.5-30.6000114.1
509A42.2Very low51.2Low92 Ų92161.5 Ų161.576%0.7684%0.844SS**  trans-111.246.217500000112.3
510T45.1Very low49.5Very low129 Ų129162.6 Ų162.679%0.79184%0.844SS**SBendtrans-151.843.5167.743.40000112.7
511V47.3Very low47.7Very low138 Ų138162.8 Ų162.884%0.83685%0.845SS**  trans-148.678.4162.5-170.50000109.9
512E37.1Very low46.2Very low184 Ų184160.6 Ų160.686%0.8684%0.842SS**SBendtrans171.8122.9159.3-102.9171.7-167.800106.3
513T38.5Very low44.9Very low118 Ų118164.2 Ų164.272%0.72485%0.851SS**  cis-170.3112.7-1.1-6.70000104.1K515T513-K515 PolarHBondContact O-N 2.67Å
514R43.6Very low44Very low248 Ų248159.2 Ų159.294%0.93685%0.847SS**  trans-72111.3156.7-100.3-177.4172.4175.6-2.3106.5
515K41.5Very low43.4Very low186 Ų186161.7 Ų161.781%0.80985%0.854SS**  trans161.1124.6160.7-94.4167.8-172.7-171.30105.1T513T513-K515 PolarHBondContact O-N 2.67Å
516Q36Very low42.7Very low185 Ų185164.4 Ų164.486%0.86486%0.861SS**  cis-157.3153.330.4-100.9158.5-26.500109.6
517A45.7Very low42.3Very low101 Ų101161.4 Ų161.484%0.83586%0.859SS**  trans-78152.1170.500000112
518Q32.4Very low42Very low179 Ų179159.8 Ų159.884%0.83687%0.866SS**  trans-35.1168.6158.5-100.4176.9-4.600116.6
519P51.6Low41.9Very low192 Ų192159.3 Ų159.3100%1.24786%0.864SS**  cis-106.6033.24.718.3000116.7

Retrieved 519 of 519 residues in 212.1 ms (Link to these results)