A0A096MV09_PAPAN Loading...

Neutral amino acid transporter 9

AlphaFold DB , UniProt , Accession A0A096MV09, Species PAPAN (Papio anubis, Olive baboon), Gene SLC38A9, Length 561 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	30.5	Very low	32.3	Very low	244 Å²	244	156.6 Å²	156.6	100%	1.202	83%	0.83	S	S	*	*				0	118.3	0	-153	168.7	-175.9	0	0	107
2	A	32.2	Very low	31.8	Very low	91 Å²	91	148.8 Å²	148.8	75%	0.752	82%	0.815	S	S	*	*			trans	39.4	122.8	157.9	0	0	0	0	0	122.4
3	N	33.7	Very low	31.4	Very low	146 Å²	146	148.4 Å²	148.4	78%	0.781	82%	0.82	S	S	*	*				42.8	139.6	124.2	-89.2	5	0	0	0	119.5
4	M	34.6	Very low	31.1	Very low	145 Å²	145	145.4 Å²	145.4	71%	0.714	82%	0.815	S	S	*	*				171.3	144.5	51.6	-131.1	153.8	76.9	0	0	110.7
5	N	36.9	Very low	31	Very low	135 Å²	135	148.5 Å²	148.5	72%	0.722	82%	0.816	S	S	*	*			trans	60.6	121.2	137.2	-73.7	6.4	0	0	0	125.4
6	S	31.5	Very low	30.8	Very low	109 Å²	109	146.6 Å²	146.6	76%	0.762	81%	0.81	S	S	*	*				134.8	112.9	100.7	59.5	0	0	0	0	117.8
7	D	36	Very low	30.6	Very low	155 Å²	155	147.9 Å²	147.9	83%	0.829	82%	0.815	S	S	*	*				54.9	123	126.9	-74.9	-13.7	0	0	0	126.6
8	S	33.3	Very low	30.5	Very low	109 Å²	109	149.8 Å²	149.8	76%	0.762	82%	0.817	S	S	*	*				121.5	127.1	116.4	69.1	0	0	0	0	118.3
9	R	27.3	Very low	30.4	Very low	252 Å²	252	152.1 Å²	152.1	95%	0.951	82%	0.818	S	S	*	*			trans	-179.8	135.6	132	-98.1	172.5	-166.9	-172.3	4.8	114.9
10	H	28.6	Very low	30.2	Very low	175 Å²	175	156.4 Å²	156.4	81%	0.81	82%	0.822	S	S	*	*			trans	-71.8	173.1	166.6	-84	-83.3	0	0	0	112.8
11	L	31.3	Very low	30.1	Very low	162 Å²	162	156 Å²	156	85%	0.848	82%	0.821	S	S	*	*			cis	177.1	152.2	-16.1	-172.3	103.6	0	0	0	106.8
12	G	25.3	Very low	30.5	Very low	63 Å²	63	150.6 Å²	150.6	65%	0.649	80%	0.804	S	S	*	*			trans	147	98.3	154	0	0	0	0	0	121.2
13	T	26.9	Very low	30.3	Very low	143 Å²	143	149.6 Å²	149.6	88%	0.877	80%	0.802	S	S	*	*			trans	14.6	152	140.9	56.7	0	0	0	0	122.9
14	S	26.9	Very low	30.4	Very low	107 Å²	107	149 Å²	149	75%	0.748	81%	0.806	S	S	*	*			cis	-170.7	168.7	14.5	61.5	0	0	0	0	113.8
15	K	29.4	Very low	30.3	Very low	192 Å²	192	150.6 Å²	150.6	84%	0.835	81%	0.814	S	S	*	*			trans	101.2	114.1	149.7	-80.1	-167.7	172.6	175.8	0	124.2
16	V	28.8	Very low	29.9	Very low	118 Å²	118	152 Å²	152	72%	0.715	82%	0.821	S	S	*	*				66.8	120.8	129.5	-172.9	0	0	0	0	123.1
17	D	27.9	Very low	30.2	Very low	168 Å²	168	152.8 Å²	152.8	90%	0.898	82%	0.816	S	S	*	*				-168.8	158.8	125.1	-105.1	-21	0	0	0	114.2
18	H	27.5	Very low	29.9	Very low	182 Å²	182	154.6 Å²	154.6	84%	0.843	82%	0.819	S	S	*	*			trans	-102.9	155.9	-161.5	-120.9	-50.1	0	0	0	115.7
19	K	28.6	Very low	29.9	Very low	194 Å²	194	158.4 Å²	158.4	84%	0.843	82%	0.823	S	S	*	*			trans	91.3	117.3	153.4	-75.2	-178.4	175.1	177.6	0	122
20	R	26	Very low	30.2	Very low	238 Å²	238	154.2 Å²	154.2	90%	0.898	81%	0.814	S	S	*	*				179.8	131.8	114.3	-100.3	-179.7	-175.4	177.4	2.5	113.9
21	D	28.7	Very low	30.6	Very low	148 Å²	148	152.4 Å²	152.4	79%	0.791	82%	0.818	S	S	*	*			trans	17.5	141	158.9	-55.2	-30.4	0	0	0	124.4
22	P	38.9	Very low	31	Very low	130 Å²	130	149.2 Å²	149.2	84%	0.844	81%	0.809	S	S	*	*			trans	-118.9	132.3	150.2	33.8	-19.7	0	0	0	113.4
23	G	28.3	Very low	31.6	Very low	70 Å²	70	151 Å²	151	72%	0.722	80%	0.804	S	S	*	*			trans	-78.7	-175.3	173.5	0	0	0	0	0	114.9
24	P	35.4	Very low	32.3	Very low	134 Å²	134	151 Å²	151	87%	0.87	80%	0.798	S	S	*	*			trans	-79.1	138.7	-165.8	31.7	-33.4	0	0	0	113.2
25	M	32.6	Very low	32.9	Very low	179 Å²	179	156.5 Å²	156.5	88%	0.882	80%	0.802	S	S	*	*			trans	-86.6	110.2	179.6	-153.4	-177.6	-60.4	0	0	109.8
26	N	29.5	Very low	33.3	Very low	163 Å²	163	152 Å²	152	87%	0.872	80%	0.795	S	S	*	*			trans	-76.5	123.1	173.2	-105	-16.4	0	0	0	110
27	I	36.6	Very low	33.6	Very low	127 Å²	127	154.6 Å²	154.6	65%	0.651	80%	0.796	S	S	*	*			trans	-104.3	110.5	169.3	-58	174.1	0	0	0	107.5	F29	I27-F29 HydrophobicContact CG2-CD2 4.3Å; I27-F29 HydrophobicContact CG2-CE2 3.92Å; I27-F29 HydrophobicContact CG2-CZ 4.23Å
28	Q	30	Very low	33.7	Very low	192 Å²	192	156.3 Å²	156.3	90%	0.897	79%	0.79	S	S	*	*	P	Polyproline II helix	trans	-85.1	132.6	167.8	-84.5	173.1	-25.7	0	0	109.5
29	F	33.7	Very low	34.2	Very low	190 Å²	190	153.4 Å²	153.4	83%	0.833	79%	0.788	S	S	*	*	P	Polyproline II helix	trans	-100.4	137.3	174.6	-78.5	-86.6	0	0	0	110.9	I27	I27-F29 HydrophobicContact CG2-CD2 4.3Å; I27-F29 HydrophobicContact CG2-CE2 3.92Å; I27-F29 HydrophobicContact CG2-CZ 4.23Å
30	E	32.4	Very low	34.6	Very low	164 Å²	164	153.2 Å²	153.2	77%	0.766	79%	0.787	S	S	*	*	P	Polyproline II helix	trans	-75.1	147.5	174.2	-92.5	-168.7	150.9	0	0	112.7	S32	E30-S32 PolarHBondContact O-N 3.36Å
31	P	38.9	Very low	35.1	Very low	137 Å²	137	150.7 Å²	150.7	89%	0.89	78%	0.779	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.4	-0.9	-166.3	-7.7	26.8	0	0	0	115.5
32	S	39.4	Very low	35.6	Very low	94 Å²	94	147.7 Å²	147.7	66%	0.657	76%	0.762	S	S	*	*	T	Hydrogen-bonded Turn	trans	-100.6	-1.6	-169.6	45.5	0	0	0	0	114.9	E30 L34	E30-S32 PolarHBondContact O-N 3.36Å; S32-L34 PolarHBondContact O-N 3.11Å
33	D	38	Very low	35.4	Very low	102 Å²	102	148.1 Å²	148.1	55%	0.545	75%	0.753	S	S	.	*			trans	-85.2	97	-178.1	-154.7	-9.4	0	0	0	112.3	R35 S36	D33-R35 PolarHBondContact O-N 3.37Å; D33-R35 VanDerWaalsContact O-N 3.1Å; D33-R35 PolarHBondContact OD1-N 2.96Å; D33-S36 WeakPolarHBondContact O-CB 3.34Å; D33-S36 PolarHBondContact O-N 3.04Å; D33-S36 VanDerWaalsContact O-N 3.13Å; D33-S36 PolarHBondContact O-OG 2.98Å
34	L	41	Very low	36.2	Very low	143 Å²	143	149.7 Å²	149.7	75%	0.749	75%	0.75	S	S	*	*	G	3₁₀ helix	trans	-64.4	-6.2	177.4	-93.9	150.6	0	0	0	113.9	S32 S36	S32-L34 PolarHBondContact O-N 3.11Å; L34-S36 VanDerWaalsContact C-N 3.26Å; L34-S36 PolarHBondContact O-N 3.26Å
35	R	39.3	Very low	36.4	Very low	222 Å²	222	148.1 Å²	148.1	84%	0.838	74%	0.738	S	S	*	*	G	3₁₀ helix	trans	-70	-19.7	168.9	-80.8	180	167.3	-175.8	-4.2	113.6	D33 K37	D33-R35 PolarHBondContact O-N 3.37Å; D33-R35 VanDerWaalsContact O-N 3.1Å; D33-R35 PolarHBondContact OD1-N 2.96Å; R35-K37 VanDerWaalsContact C-N 3.28Å; R35-K37 PolarHBondContact O-N 3.16Å
36	S	38.2	Very low	36.4	Very low	98 Å²	98	146.7 Å²	146.7	69%	0.685	73%	0.734	S	S	*	*	G	3₁₀ helix	trans	-74.6	-9.8	180	64.1	0	0	0	0	115	D33 L34	D33-S36 WeakPolarHBondContact O-CB 3.34Å; D33-S36 PolarHBondContact O-N 3.04Å; D33-S36 VanDerWaalsContact O-N 3.13Å; D33-S36 PolarHBondContact O-OG 2.98Å; L34-S36 VanDerWaalsContact C-N 3.26Å; L34-S36 PolarHBondContact O-N 3.26Å
37	K	34.6	Very low	36.6	Very low	172 Å²	172	145.8 Å²	145.8	75%	0.748	73%	0.728	S	S	*	*	G	3₁₀ helix	trans	-108	15	-171.1	-70.6	-171.9	178.7	179.8	0	115.9	R35	R35-K37 VanDerWaalsContact C-N 3.28Å; R35-K37 PolarHBondContact O-N 3.16Å
38	R	31.2	Very low	36.2	Very low	204 Å²	204	146 Å²	146	77%	0.77	73%	0.734	S	S	*	*	S	Bend	trans	-100.3	136.9	169.9	-66.4	-171.2	-178.5	-165.2	0.4	110.3	F40	R38-F40 PolarHBondContact O-N 3.08Å
39	P	36.4	Very low	36	Very low	121 Å²	121	143.5 Å²	143.5	79%	0.786	73%	0.727	S	S	*	*	S	Bend	trans	-61.8	109.1	166.9	25.2	-29.4	0	0	0	108.4
40	F	38.1	Very low	35.7	Very low	189 Å²	189	140.2 Å²	140.2	83%	0.829	72%	0.723	S	S	*	*			trans	33.7	83.3	165.2	-53.4	-79.5	0	0	0	116.8	R38	R38-F40 PolarHBondContact O-N 3.08Å
41	Y	35.3	Very low	35.7	Very low	186 Å²	186	138.6 Å²	138.6	73%	0.729	72%	0.719	S	S	*	*			trans	-86.3	109.2	157.1	-175.7	-103	0	0	0	108.6	E43	Y41-E43 HydrophobicContact CD1-CG 4.29Å; Y41-E43 HydrophobicContact CE1-CG 3.74Å
42	I	39.6	Very low	35.3	Very low	84 Å²	84	140 Å²	140	43%	0.431	71%	0.713	S	S	.	*			trans	-99.9	113.6	-179.8	-59.9	170.8	0	0	0	107.9	K66	I42-K66 HydrophobicContact CG2-CD 4.42Å
43	E	35.6	Very low	35.4	Very low	140 Å²	140	142 Å²	142	65%	0.654	72%	0.722	S	S	*	*			trans	-68.9	134.2	172.8	-80.9	-178.8	160.4	0	0	111.1	Y41 T45	Y41-E43 HydrophobicContact CD1-CG 4.29Å; Y41-E43 HydrophobicContact CE1-CG 3.74Å; E43-T45 PolarHBondContact O-N 3.31Å; E43-T45 VanDerWaalsContact O-N 3.13Å
44	P	43.7	Very low	35.4	Very low	103 Å²	103	144 Å²	144	67%	0.669	73%	0.731	S	S	*	*			trans	-63.7	115.8	171.3	24.8	-29.8	0	0	0	108.6	N46	P44-N46 PolarHBondContact O-N 3.11Å
45	T	41.5	Very low	35.5	Very low	100 Å²	100	145.8 Å²	145.8	61%	0.613	74%	0.735	S	S	*	*			trans	-85.1	107.2	-178	-0.9	0	0	0	0	108	E43 K66	E43-T45 PolarHBondContact O-N 3.31Å; E43-T45 VanDerWaalsContact O-N 3.13Å; T45-K66 PolarHBondContact OG1-NZ 3.32Å; T45-K66 VanDerWaalsContact OG1-NZ 3.08Å
46	N	31.9	Very low	35.6	Very low	150 Å²	150	146.8 Å²	146.8	80%	0.802	74%	0.739	S	S	*	*			trans	17.8	105.5	165.4	-69.1	-24.1	0	0	0	118.8	P44	P44-N46 PolarHBondContact O-N 3.11Å
47	I	33.7	Very low	36.2	Very low	144 Å²	144	144.2 Å²	144.2	74%	0.738	72%	0.719	S	S	*	*			trans	-133.1	112.7	148.5	-55.8	177.4	0	0	0	107.4
48	V	28.6	Very low	37.3	Very low	130 Å²	130	139.2 Å²	139.2	79%	0.788	71%	0.706	S	S	*	*			trans	-79.7	140	-175.2	-179	0	0	0	0	110.6
49	N	25.2	Very low	38.5	Very low	140 Å²	140	136 Å²	136	75%	0.749	70%	0.704	S	S	*	*			trans	-90.2	121.2	-179.3	-177.6	17.9	0	0	0	110.6
50	V	28.3	Very low	39.6	Very low	122 Å²	122	135.3 Å²	135.3	74%	0.739	69%	0.69	S	S	*	*			trans	-145.9	102.9	146.9	-173	0	0	0	0	109.3
51	N	31.3	Very low	40.7	Very low	130 Å²	130	126.4 Å²	126.4	70%	0.695	65%	0.651	S	S	*	*	S	Bend	trans	67.8	117.7	154.6	-66.1	-12.4	0	0	0	120.7
52	H	31.6	Very low	42.1	Very low	165 Å²	165	119.5 Å²	119.5	76%	0.764	63%	0.63	S	S	*	*	S	Bend	trans	78.3	96.2	161.7	-71.1	-73.1	0	0	0	119.2
53	V	39.6	Very low	43.4	Very low	138 Å²	138	117.3 Å²	117.3	84%	0.836	63%	0.625	S	S	*	*			trans	53.1	61.9	142.6	-160.7	0	0	0	0	116
54	I	38.8	Very low	44.9	Very low	144 Å²	144	112 Å²	112	74%	0.738	60%	0.601	S	S	*	*			trans	-134.1	128.1	156.9	-57.8	-178.8	0	0	0	111
55	Q	43.5	Very low	46	Very low	179 Å²	179	109.2 Å²	109.2	84%	0.836	58%	0.58	S	S	*	*			trans	-24	115.6	173.9	-138.5	146.4	-25.1	0	0	116.3	V57	Q55-V57 PolarHBondContact O-N 3.1Å
56	R	41.8	Very low	47.4	Very low	243 Å²	243	108.7 Å²	108.7	92%	0.917	57%	0.569	S	S	*	*	P	Polyproline II helix	trans	-61.7	128.6	161.8	-79.5	-177	-176.5	156.9	1.2	108.9	S58	R56-S58 PolarHBondContact O-N 3.17Å
57	V	50.3	Low	49.2	Very low	45 Å²	45	106.3 Å²	106.3	27%	0.273	55%	0.549	S	S	.	.	P	Polyproline II helix	trans	-61.2	125	163.3	-179.8	0	0	0	0	107.1	Q55 A61 A104	Q55-V57 PolarHBondContact O-N 3.1Å; V57-A61 HydrophobicContact CG1-CB 3.8Å; V57-A104 HydrophobicContact CG1-CB 4.05Å; V57-A104 HydrophobicContact CG2-CB 3.73Å
58	S	56.6	Low	50.9	Low	67 Å²	67	102.9 Å²	102.9	47%	0.469	53%	0.531	S	S	.	.	P	Polyproline II helix	trans	-59	140.7	178.1	171.2	0	0	0	0	110.4	R56 H60 A61 S62	R56-S58 PolarHBondContact O-N 3.17Å; S58-H60 PolarHBondContact O-N 3.48Å; S58-H60 PolarHBondContact OG-N 2.92Å; S58-A61 WeakPolarHBondContact O-CB 3.32Å; S58-A61 PolarHBondContact O-N 3.12Å; S58-S62 PolarHBondContact O-N 3.41Å
59	D	56.9	Low	52.8	Low	137 Å²	137	101.6 Å²	101.6	73%	0.733	52%	0.516	S	S	*	.	H	α-helix	trans	-51	-32.2	175.8	-62.4	-37.8	0	0	0	112	S62 A63	D59-S62 PolarHBondContact O-N 2.92Å; D59-A63 WeakPolarHBondContact O-CB 3.39Å; D59-A63 PolarHBondContact O-N 2.92Å
60	H	60.3	Low	55	Low	106 Å²	106	101.5 Å²	101.5	49%	0.491	51%	0.507	S	S	.	.	H	α-helix	trans	-61.9	-43.8	175	-169.1	-94.5	0	0	0	113	S58 A63 M64	S58-H60 PolarHBondContact O-N 3.48Å; S58-H60 PolarHBondContact OG-N 2.92Å; H60-A63 PolarHBondContact O-N 3.48Å; H60-M64 WeakPolarHBondContact O-CB 3.41Å; H60-M64 PolarHBondContact O-N 3.42Å
61	A	60.5	Low	57	Low	1 Å²	1	98.5 Å²	98.5	1%	0.008	48%	0.482	C	S	.	.	H	α-helix	trans	-70.1	-35.9	-179.8	0	0	0	0	0	112	V57 S58 M64 N65 Y96 Y98	V57-A61 HydrophobicContact CG1-CB 3.8Å; S58-A61 WeakPolarHBondContact O-CB 3.32Å; S58-A61 PolarHBondContact O-N 3.12Å; A61-M64 PolarHBondContact O-N 3.42Å; A61-N65 PolarHBondContact O-N 2.95Å; A61-N65 VanDerWaalsContact O-N 3.09Å; A61-Y96 HydrophobicContact CB-CD1 4.01Å; A61-Y96 HydrophobicContact CB-CD2 4.15Å; A61-Y96 HydrophobicContact CB-CE1 3.78Å; A61-Y96 HydrophobicContact CB-CE2 3.95Å; A61-Y96 HydrophobicContact CB-CG 4.23Å; A61-Y98 PolarHBondContact O-OH 3.14Å
62	S	64.3	Low	58.6	Low	41 Å²	41	95.7 Å²	95.7	29%	0.287	47%	0.473	S	S	.	.	H	α-helix	trans	-64.7	-45.2	174	-177.5	0	0	0	0	112	S58 D59 M64 N65 K66	S58-S62 PolarHBondContact O-N 3.41Å; D59-S62 PolarHBondContact O-N 2.92Å; S62-M64 VanDerWaalsContact C-N 3.32Å; S62-M64 PolarHBondContact O-N 3.44Å; S62-N65 PolarHBondContact O-N 3.34Å; S62-K66 PolarHBondContact O-N 3.16Å
63	A	68.3	Low	60.3	Low	39 Å²	39	98.1 Å²	98.1	32%	0.322	48%	0.475	S	S	.	.	H	α-helix	trans	-61.1	-42.3	175.9	0	0	0	0	0	111.6	D59 H60 K66 R67	D59-A63 WeakPolarHBondContact O-CB 3.39Å; D59-A63 PolarHBondContact O-N 2.92Å; H60-A63 PolarHBondContact O-N 3.48Å; A63-K66 PolarHBondContact O-N 3Å; A63-R67 PolarHBondContact O-N 3Å; A63-R67 VanDerWaalsContact O-N 3.07Å
64	M	66.9	Low	61.5	Low	29 Å²	29	94.8 Å²	94.8	14%	0.143	45%	0.452	C	S	.	.	H	α-helix	trans	-62.7	-45.5	179.4	-167.7	61.6	164.9	0	0	112.7	H60 A61 S62 K66 R67 I68 V88 P90	H60-M64 WeakPolarHBondContact O-CB 3.41Å; H60-M64 PolarHBondContact O-N 3.42Å; A61-M64 PolarHBondContact O-N 3.42Å; S62-M64 VanDerWaalsContact C-N 3.32Å; S62-M64 PolarHBondContact O-N 3.44Å; M64-K66 PolarHBondContact O-N 3.43Å; M64-R67 WeakPolarHBondContact O-CB 3.5Å; M64-R67 PolarHBondContact O-N 3.2Å; M64-R67 VanDerWaalsContact O-N 3.13Å; M64-I68 HydrophobicContact CG-CD1 4.26Å; M64-I68 WeakPolarHBondContact O-CG1 3.45Å; M64-I68 PolarHBondContact O-N 2.72Å; M64-V88 WeakPolarHBondContact CE-O 3.42Å; M64-P90 HydrophobicContact CE-CB 3.62Å; M64-P90 VanDerWaalsContact CE-CD 3.44Å; M64-P90 HydrophobicContact CE-CG 3.43Å; M64-P90 VanDerWaalsContact CE-CG 3.43Å; M64-P90 VanDerWaalsContact CE-N 3.3Å; M64-P90 HydrophobicContact CG-CG 4.41Å
65	N	66.4	Low	62.6	Low	43 Å²	43	90.7 Å²	90.7	23%	0.23	43%	0.434	C	S	.	.	H	α-helix	trans	-63.3	-41.1	179.6	-172.2	31.2	0	0	0	112.4	A61 S62 R67 I68 H69 Y98	A61-N65 PolarHBondContact O-N 2.95Å; A61-N65 VanDerWaalsContact O-N 3.09Å; S62-N65 PolarHBondContact O-N 3.34Å; N65-R67 VanDerWaalsContact C-N 3.28Å; N65-R67 PolarHBondContact O-N 3.5Å; N65-I68 PolarHBondContact O-N 3.17Å; N65-H69 PolarHBondContact O-CD2 2.74Å; N65-H69 PolarHBondContact O-N 3.46Å; N65-H69 PolarHBondContact OD1-CD2 3.22Å; N65-Y98 HydrophobicContact CB-CE2 4.06Å; N65-Y98 WeakPolarHBondContact CB-OH 3.49Å
66	K	71.1	Confident	63.4	Low	90 Å²	90	86 Å²	86	39%	0.391	42%	0.418	S	S	.	.	H	α-helix	trans	-62.5	-37.2	174.3	-70.6	-177.7	-178.7	-179.7	0	111.6	I42 T45 S62 A63 M64 Y70	I42-K66 HydrophobicContact CG2-CD 4.42Å; T45-K66 PolarHBondContact OG1-NZ 3.32Å; T45-K66 VanDerWaalsContact OG1-NZ 3.08Å; S62-K66 PolarHBondContact O-N 3.16Å; A63-K66 PolarHBondContact O-N 3Å; M64-K66 PolarHBondContact O-N 3.43Å; K66-Y70 WeakPolarHBondContact O-CB 3.29Å; K66-Y70 PolarHBondContact O-N 2.79Å
67	R	70.3	Confident	64.2	Low	99 Å²	99	81.5 Å²	81.5	37%	0.374	42%	0.42	S	S	.	.	H	α-helix	trans	-63.5	-47.6	175.4	-164.2	176.7	-171.7	-162.1	0.9	111.3	A63 M64 N65 Y70 Y71 V88	A63-R67 PolarHBondContact O-N 3Å; A63-R67 VanDerWaalsContact O-N 3.07Å; M64-R67 WeakPolarHBondContact O-CB 3.5Å; M64-R67 PolarHBondContact O-N 3.2Å; M64-R67 VanDerWaalsContact O-N 3.13Å; N65-R67 VanDerWaalsContact C-N 3.28Å; N65-R67 PolarHBondContact O-N 3.5Å; R67-Y70 WeakPolarHBondContact O-CB 3.41Å; R67-Y70 PolarHBondContact O-N 2.96Å; R67-Y71 HydrophobicContact CG-CD2 4.23Å; R67-Y71 HydrophobicContact CG-CE2 3.9Å; R67-Y71 WeakPolarHBondContact O-CD2 3.48Å; R67-Y71 PolarHBondContact O-N 3.18Å; R67-V88 HydrophobicContact CG-CG1 3.9Å
68	I	68.3	Low	64.5	Low	72 Å²	72	83.6 Å²	83.6	37%	0.369	44%	0.442	S	S	.	.	H	α-helix	trans	-63	-44.8	178.5	-66.1	169.3	0	0	0	111.3	M64 N65 Y70 Y71 S72 P90	M64-I68 HydrophobicContact CG-CD1 4.26Å; M64-I68 WeakPolarHBondContact O-CG1 3.45Å; M64-I68 PolarHBondContact O-N 2.72Å; N65-I68 PolarHBondContact O-N 3.17Å; I68-Y70 VanDerWaalsContact C-N 3.26Å; I68-Y70 PolarHBondContact O-N 2.99Å; I68-Y71 PolarHBondContact O-N 3.08Å; I68-S72 WeakPolarHBondContact O-CB 3.27Å; I68-S72 PolarHBondContact O-N 3.44Å; I68-P90 HydrophobicContact CD1-CG 4.03Å
69	H	68.4	Low	64.5	Low	103 Å²	103	84.8 Å²	84.8	48%	0.477	44%	0.443	S	S	.	.	H	α-helix	trans	-60.8	-35	175.9	-89.1	-63.5	0	0	0	113.1	N65 R73	N65-H69 PolarHBondContact O-CD2 2.74Å; N65-H69 PolarHBondContact O-N 3.46Å; N65-H69 PolarHBondContact OD1-CD2 3.22Å; H69-R73 WeakPolarHBondContact O-CG 3.49Å; H69-R73 PolarHBondContact O-N 2.92Å; H69-R73 VanDerWaalsContact O-N 3.11Å
70	Y	72	Confident	64.6	Low	139 Å²	139	87.3 Å²	87.3	55%	0.545	45%	0.448	S	S	.	.	H	α-helix	trans	-63.7	-51.2	175.3	175.4	-101.5	0	0	0	111.5	K66 R67 I68 S72 R73 L74	K66-Y70 WeakPolarHBondContact O-CB 3.29Å; K66-Y70 PolarHBondContact O-N 2.79Å; R67-Y70 WeakPolarHBondContact O-CB 3.41Å; R67-Y70 PolarHBondContact O-N 2.96Å; I68-Y70 VanDerWaalsContact C-N 3.26Å; I68-Y70 PolarHBondContact O-N 2.99Å; Y70-S72 VanDerWaalsContact C-N 3.34Å; Y70-S72 PolarHBondContact O-N 3.37Å; Y70-R73 PolarHBondContact O-N 3.29Å; Y70-R73 VanDerWaalsContact O-N 3.11Å; Y70-L74 HydrophobicContact CD1-CD1 3.87Å; Y70-L74 HydrophobicContact CE1-CD1 3.32Å; Y70-L74 HydrophobicContact CE1-CG 4.3Å; Y70-L74 HydrophobicContact CE2-CD1 4.37Å; Y70-L74 PolarHBondContact O-N 3.23Å; Y70-L74 VanDerWaalsContact O-N 3.15Å
71	Y	69.6	Low	64.4	Low	58 Å²	58	86.7 Å²	86.7	23%	0.227	46%	0.461	C	S	.	.	H	α-helix	trans	-63.3	-39.7	177.2	-75.7	-78.8	0	0	0	112.3	R67 I68 R73 L74 T75 A84 V88	R67-Y71 HydrophobicContact CG-CD2 4.23Å; R67-Y71 HydrophobicContact CG-CE2 3.9Å; R67-Y71 WeakPolarHBondContact O-CD2 3.48Å; R67-Y71 PolarHBondContact O-N 3.18Å; I68-Y71 PolarHBondContact O-N 3.08Å; Y71-R73 PolarHBondContact O-N 3.44Å; Y71-L74 HydrophobicContact CD1-CD1 4.43Å; Y71-L74 WeakPolarHBondContact O-CB 3.46Å; Y71-L74 PolarHBondContact O-N 2.95Å; Y71-T75 WeakPolarHBondContact O-CG2 3.39Å; Y71-T75 PolarHBondContact O-N 3.01Å; Y71-T75 PolarHBondContact O-OG1 3.16Å; Y71-A84 HydrophobicContact CD1-CB 4.32Å; Y71-A84 HydrophobicContact CG-CB 4.02Å; Y71-V88 HydrophobicContact CD2-CG1 3.8Å; Y71-V88 HydrophobicContact CE2-CG1 3.53Å
72	S	65	Low	64.3	Low	72 Å²	72	90.3 Å²	90.3	50%	0.503	48%	0.48	S	S	.	.	H	α-helix	trans	-61.9	-25.7	175.2	175.9	0	0	0	0	113.5	I68 Y70 T75	I68-S72 WeakPolarHBondContact O-CB 3.27Å; I68-S72 PolarHBondContact O-N 3.44Å; Y70-S72 VanDerWaalsContact C-N 3.34Å; Y70-S72 PolarHBondContact O-N 3.37Å; S72-T75 WeakPolarHBondContact CA-OG1 3.3Å; S72-T75 PolarHBondContact O-OG1 3.05Å
73	R	67.8	Low	64.1	Low	216 Å²	216	93.8 Å²	93.8	82%	0.815	49%	0.494	S	S	*	.	H	α-helix	trans	-83	-24.5	173.6	-75.3	-180	178.6	-166.3	0.6	112.9	H69 Y70 Y71	H69-R73 WeakPolarHBondContact O-CG 3.49Å; H69-R73 PolarHBondContact O-N 2.92Å; H69-R73 VanDerWaalsContact O-N 3.11Å; Y70-R73 PolarHBondContact O-N 3.29Å; Y70-R73 VanDerWaalsContact O-N 3.11Å; Y71-R73 PolarHBondContact O-N 3.44Å
74	L	64.6	Low	63.8	Low	67 Å²	67	93 Å²	93	35%	0.351	49%	0.488	S	S	.	.	H	α-helix	trans	-79.7	-28.7	174.7	-68.5	174	0	0	0	112.2	Y70 Y71 T76	Y70-L74 HydrophobicContact CD1-CD1 3.87Å; Y70-L74 HydrophobicContact CE1-CD1 3.32Å; Y70-L74 HydrophobicContact CE1-CG 4.3Å; Y70-L74 HydrophobicContact CE2-CD1 4.37Å; Y70-L74 PolarHBondContact O-N 3.23Å; Y70-L74 VanDerWaalsContact O-N 3.15Å; Y71-L74 HydrophobicContact CD1-CD1 4.43Å; Y71-L74 WeakPolarHBondContact O-CB 3.46Å; Y71-L74 PolarHBondContact O-N 2.95Å; L74-T76 PolarHBondContact O-N 3.4Å; L74-T76 VanDerWaalsContact O-N 3.08Å
75	T	61.5	Low	63.7	Low	59 Å²	59	94.2 Å²	94.2	36%	0.362	50%	0.498	S	S	.	.			trans	-72.2	99.8	175.8	53.8	0	0	0	0	110.4	Y71 S72 L82	Y71-T75 WeakPolarHBondContact O-CG2 3.39Å; Y71-T75 PolarHBondContact O-N 3.01Å; Y71-T75 PolarHBondContact O-OG1 3.16Å; S72-T75 WeakPolarHBondContact CA-OG1 3.3Å; S72-T75 PolarHBondContact O-OG1 3.05Å; T75-L82 VanDerWaalsContact CG2-O 3.24Å; T75-L82 WeakPolarHBondContact CG2-O 3.47Å
76	T	61.2	Low	63.3	Low	81 Å²	81	99.5 Å²	99.5	50%	0.497	53%	0.526	S	S	.	.			trans	-81.3	150.3	159.1	42	0	0	0	0	109.2	L74 A78 D79	L74-T76 PolarHBondContact O-N 3.4Å; L74-T76 VanDerWaalsContact O-N 3.08Å; T76-A78 PolarHBondContact O-N 3.45Å; T76-D79 PolarHBondContact O-N 3.18Å
77	P	58.7	Low	63.1	Low	148 Å²	148	102.2 Å²	102.2	96%	0.961	54%	0.54	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.7	-13.5	-173.2	-23.6	32.7	0	0	0	115.6
78	A	55.6	Low	62.6	Low	88 Å²	88	97.5 Å²	97.5	73%	0.727	52%	0.522	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.5	-23.1	-174.5	0	0	0	0	0	114.4	T76	T76-A78 PolarHBondContact O-N 3.45Å
79	D	57.7	Low	62.2	Low	93 Å²	93	97.7 Å²	97.7	50%	0.497	53%	0.527	S	S	.	.			trans	-110.4	97.8	-171.2	-84.8	-26.5	0	0	0	113	T76 A81 L82	T76-D79 PolarHBondContact O-N 3.18Å; D79-A81 PolarHBondContact O-N 2.88Å; D79-L82 HydrophobicContact CB-CD1 4.34Å; D79-L82 PolarHBondContact O-N 3.12Å
80	K	57.5	Low	61.6	Low	189 Å²	189	94.2 Å²	94.2	82%	0.822	51%	0.513	S	S	*	.	G	3₁₀ helix	trans	-67.3	-8.9	173.7	-71.1	-176.7	178	179.1	0	114.1	L82 I83	K80-L82 VanDerWaalsContact C-N 3.31Å; K80-I83 HydrophobicContact CB-CD1 4.24Å; K80-I83 VanDerWaalsContact O-CD1 3.31Å; K80-I83 WeakPolarHBondContact O-CD1 3.4Å; K80-I83 WeakPolarHBondContact O-CG1 3.27Å
81	A	56.3	Low	60.8	Low	94 Å²	94	89.4 Å²	89.4	78%	0.777	51%	0.506	S	S	*	.	G	3₁₀ helix	trans	-77.6	-13.9	179.1	0	0	0	0	0	113.7	D79	D79-A81 PolarHBondContact O-N 2.88Å
82	L	58.6	Low	59.8	Low	76 Å²	76	91.7 Å²	91.7	40%	0.398	53%	0.527	S	S	.	.	G	3₁₀ helix	trans	-105.8	18.6	-175.9	-66.4	169.1	0	0	0	113.3	T75 D79 K80	T75-L82 VanDerWaalsContact CG2-O 3.24Å; T75-L82 WeakPolarHBondContact CG2-O 3.47Å; D79-L82 HydrophobicContact CB-CD1 4.34Å; D79-L82 PolarHBondContact O-N 3.12Å; K80-L82 VanDerWaalsContact C-N 3.31Å
83	I	59.8	Low	58.9	Low	114 Å²	114	93.4 Å²	93.4	59%	0.585	53%	0.528	S	S	*	.	S	Bend	trans	-66.4	136.7	174.2	-62.5	170	0	0	0	108.8	K80 P85	K80-I83 HydrophobicContact CB-CD1 4.24Å; K80-I83 VanDerWaalsContact O-CD1 3.31Å; K80-I83 WeakPolarHBondContact O-CD1 3.4Å; K80-I83 WeakPolarHBondContact O-CG1 3.27Å; I83-P85 WeakPolarHBondContact O-CD 3.19Å
84	A	63.6	Low	58.1	Low	24 Å²	24	86.8 Å²	86.8	20%	0.198	51%	0.506	C	S	.	.	P	Polyproline II helix	trans	-54.8	124.9	177.7	0	0	0	0	0	110.1	Y71 V89	Y71-A84 HydrophobicContact CD1-CB 4.32Å; Y71-A84 HydrophobicContact CG-CB 4.02Å; A84-V89 HydrophobicContact CB-CG2 3.95Å
85	P	64.3	Low	57.5	Low	53 Å²	53	86.3 Å²	86.3	34%	0.344	51%	0.508	S	S	.	.	P	Polyproline II helix	trans	-60.7	151.2	178.6	-21.7	30.7	0	0	0	112.3	I83 H87 V88 V89	I83-P85 WeakPolarHBondContact O-CD 3.19Å; P85-H87 VanDerWaalsContact CB-CE1 3.46Å; P85-H87 WeakPolarHBondContact CB-CE1 3.43Å; P85-H87 PolarHBondContact O-N 3.29Å; P85-H87 VanDerWaalsContact O-N 3.09Å; P85-V88 HydrophobicContact CB-CG2 4.1Å; P85-V88 HydrophobicContact CG-CG2 4.18Å; P85-V88 WeakPolarHBondContact O-CA 3.38Å; P85-V88 WeakPolarHBondContact O-CB 3.38Å; P85-V88 PolarHBondContact O-N 2.89Å; P85-V89 PolarHBondContact O-N 3.17Å
86	D	57.6	Low	57.2	Low	154 Å²	154	86.3 Å²	86.3	82%	0.824	50%	0.501	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.3	-28.3	-172.8	-66	-33.4	0	0	0	114.7	V88	D86-V88 PolarHBondContact O-N 3.27Å
87	H	66.8	Low	56.4	Low	147 Å²	147	86.1 Å²	86.1	68%	0.681	50%	0.5	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.8	-5.1	175.2	71.6	-87.2	0	0	0	113.7	P85	P85-H87 VanDerWaalsContact CB-CE1 3.46Å; P85-H87 WeakPolarHBondContact CB-CE1 3.43Å; P85-H87 PolarHBondContact O-N 3.29Å; P85-H87 VanDerWaalsContact O-N 3.09Å
88	V	60.5	Low	56	Low	1 Å²	1	83.3 Å²	83.3	1%	0.006	47%	0.471	C	S	.	.	T	Hydrogen-bonded Turn	trans	-103.1	-28	178.5	-176.8	0	0	0	0	111.7	M64 R67 Y71 P85 D86	M64-V88 WeakPolarHBondContact CE-O 3.42Å; R67-V88 HydrophobicContact CG-CG1 3.9Å; Y71-V88 HydrophobicContact CD2-CG1 3.8Å; Y71-V88 HydrophobicContact CE2-CG1 3.53Å; P85-V88 HydrophobicContact CB-CG2 4.1Å; P85-V88 HydrophobicContact CG-CG2 4.18Å; P85-V88 WeakPolarHBondContact O-CA 3.38Å; P85-V88 WeakPolarHBondContact O-CB 3.38Å; P85-V88 PolarHBondContact O-N 2.89Å; D86-V88 PolarHBondContact O-N 3.27Å
89	V	58.8	Low	55.3	Low	76 Å²	76	80.7 Å²	80.7	46%	0.461	45%	0.447	S	S	.	.	S	Bend	trans	-76.9	131.2	173.1	-176.7	0	0	0	0	107.5	A84 P85 G91	A84-V89 HydrophobicContact CB-CG2 3.95Å; P85-V89 PolarHBondContact O-N 3.17Å; V89-G91 PolarHBondContact O-N 3.03Å
90	P	56.2	Low	54.4	Low	29 Å²	29	83 Å²	83	19%	0.188	47%	0.467	C	S	.	.	P	Polyproline II helix	trans	-61.6	138.2	178.9	2.5	6.6	0	0	0	109	M64 I68 E94	M64-P90 HydrophobicContact CE-CB 3.62Å; M64-P90 VanDerWaalsContact CE-CD 3.44Å; M64-P90 HydrophobicContact CE-CG 3.43Å; M64-P90 VanDerWaalsContact CE-CG 3.43Å; M64-P90 VanDerWaalsContact CE-N 3.3Å; M64-P90 HydrophobicContact CG-CG 4.41Å; I68-P90 HydrophobicContact CD1-CG 4.03Å; P90-E94 HydrophobicContact CB-CB 3.86Å
91	G	54.5	Low	53.7	Low	38 Å²	38	81.6 Å²	81.6	39%	0.392	47%	0.468	S	S	.	.	P	Polyproline II helix	trans	-58.7	159.7	165.5	0	0	0	0	0	110.6	V89 E93 E94	V89-G91 PolarHBondContact O-N 3.03Å; G91-E93 PolarHBondContact O-N 3.5Å; G91-E94 PolarHBondContact O-N 3.31Å
92	P	49.8	Very low	53.1	Low	106 Å²	106	79.6 Å²	79.6	69%	0.688	46%	0.457	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58	-11.8	-177	20.1	-31.1	0	0	0	115.1	S109	P92-S109 PolarHBondContact O-OG 3.04Å
93	E	46.7	Very low	52.4	Low	108 Å²	108	77.8 Å²	77.8	51%	0.505	45%	0.45	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.6	-9	177.4	-47	-164.8	179.5	0	0	113.9	G91 T111	G91-E93 PolarHBondContact O-N 3.5Å; E93-T111 HydrophobicContact CG-CG2 4.14Å
94	E	50.5	Low	51.7	Low	78 Å²	78	73 Å²	73	36%	0.364	43%	0.428	S	S	.	.	S	Bend	trans	-121.5	18.6	-173.2	-60.9	-164.9	152.9	0	0	113.8	P90 G91 Y96	P90-E94 HydrophobicContact CB-CB 3.86Å; G91-E94 PolarHBondContact O-N 3.31Å; E94-Y96 WeakPolarHBondContact O-CD2 3.37Å; E94-Y96 WeakPolarHBondContact O-CE2 3.43Å; E94-Y96 PolarHBondContact O-N 2.74Å
95	C	50.8	Low	50.8	Low	57 Å²	57	78 Å²	78	39%	0.385	44%	0.443	S	S	.	.			trans	-71.1	127	176	-72.8	0	0	0	0	111.9	L107	C95-L107 VanDerWaalsContact O-CB 3.26Å; C95-L107 WeakPolarHBondContact O-CB 3.43Å; C95-L107 PolarHBondContact O-N 3.29Å
96	Y	54.9	Low	49.8	Very low	58 Å²	58	80.6 Å²	80.6	23%	0.227	45%	0.448	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-111.9	132.9	173.2	-62	-96.4	0	0	0	109.2	A61 E94 Y105 K106	A61-Y96 HydrophobicContact CB-CD1 4.01Å; A61-Y96 HydrophobicContact CB-CD2 4.15Å; A61-Y96 HydrophobicContact CB-CE1 3.78Å; A61-Y96 HydrophobicContact CB-CE2 3.95Å; A61-Y96 HydrophobicContact CB-CG 4.23Å; E94-Y96 WeakPolarHBondContact O-CD2 3.37Å; E94-Y96 WeakPolarHBondContact O-CE2 3.43Å; E94-Y96 PolarHBondContact O-N 2.74Å; Y96-Y105 CarbonylContact C-O 3.54Å; Y96-Y105 VanDerWaalsContact CA-O 3.29Å; Y96-Y105 WeakPolarHBondContact CA-O 3.31Å; Y96-K106 HydrophobicContact CD1-CB 3.7Å; Y96-K106 HydrophobicContact CD1-CG 4.05Å; Y96-K106 HydrophobicContact CE1-CB 3.49Å; Y96-K106 VanDerWaalsContact CE1-CB 3.49Å; Y96-K106 HydrophobicContact CE1-CD 4.01Å; Y96-K106 HydrophobicContact CE1-CG 3.62Å
97	V	46.3	Very low	48.9	Very low	77 Å²	77	77.5 Å²	77.5	47%	0.467	43%	0.431	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.7	120.5	173.8	177.4	0	0	0	0	108.7	Y105 L107	V97-Y105 PolarHBondContact N-O 3.34Å; V97-Y105 PolarHBondContact O-N 2.91Å; V97-L107 HydrophobicContact CG2-CB 4.25Å; V97-L107 HydrophobicContact CG2-CD1 3.96Å; V97-L107 HydrophobicContact CG2-CG 4.48Å
98	Y	49.9	Very low	47.4	Very low	89 Å²	89	77.6 Å²	77.6	35%	0.349	43%	0.432	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.6	125.3	176.4	-76	-95	0	0	0	110.1	A61 N65 A104	A61-Y98 PolarHBondContact O-OH 3.14Å; N65-Y98 HydrophobicContact CB-CE2 4.06Å; N65-Y98 WeakPolarHBondContact CB-OH 3.49Å; Y98-A104 HydrophobicContact CD1-CB 3.68Å; Y98-A104 HydrophobicContact CD2-CB 4.44Å; Y98-A104 HydrophobicContact CE1-CB 3.4Å; Y98-A104 VanDerWaalsContact CE1-CB 3.4Å; Y98-A104 HydrophobicContact CE2-CB 4.19Å; Y98-A104 HydrophobicContact CG-CB 4.19Å
99	S	40.8	Very low	46.1	Very low	34 Å²	34	79.4 Å²	79.4	24%	0.238	45%	0.445	C	S	.	.	P	Polyproline II helix	trans	-74	147.5	169.1	173.5	0	0	0	0	110.2	L101 G102 S103	S99-L101 PolarHBondContact O-N 3.33Å; S99-L101 PolarHBondContact OG-N 3.37Å; S99-G102 PolarHBondContact O-N 3.43Å; S99-S103 WeakPolarHBondContact CB-O 3.46Å; S99-S103 WeakPolarHBondContact CB-OG 3.42Å; S99-S103 PolarHBondContact N-O 2.93Å
100	P	37.6	Very low	45.1	Very low	140 Å²	140	84.9 Å²	84.9	91%	0.909	46%	0.458	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.7	-20	171.5	-22.6	31.9	0	0	0	113.9	G102	P100-G102 VanDerWaalsContact C-N 3.33Å
101	L	43.4	Very low	44.1	Very low	161 Å²	161	86.7 Å²	86.7	84%	0.843	47%	0.469	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.2	11.3	178.2	-70	152.3	0	0	0	113.5	S99 S103	S99-L101 PolarHBondContact O-N 3.33Å; S99-L101 PolarHBondContact OG-N 3.37Å; L101-S103 PolarHBondContact O-N 3.25Å
102	G	43.2	Very low	43.4	Very low	52 Å²	52	90.9 Å²	90.9	54%	0.536	48%	0.478	S	S	.	.	S	Bend	trans	82	6.6	173.4	0	0	0	0	0	115.9	S99 P100	S99-G102 PolarHBondContact O-N 3.43Å; P100-G102 VanDerWaalsContact C-N 3.33Å
103	S	43.9	Very low	43.1	Very low	37 Å²	37	88.6 Å²	88.6	26%	0.259	47%	0.474	S	S	.	.	P	Polyproline II helix	trans	-90.7	128.6	172.3	41.2	0	0	0	0	110.9	S99 L101 Y105	S99-S103 WeakPolarHBondContact CB-O 3.46Å; S99-S103 WeakPolarHBondContact CB-OG 3.42Å; S99-S103 PolarHBondContact N-O 2.93Å; L101-S103 PolarHBondContact O-N 3.25Å; S103-Y105 WeakPolarHBondContact OG-CE2 3.43Å
104	A	46	Very low	43	Very low	15 Å²	15	91.6 Å²	91.6	12%	0.124	48%	0.482	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-99	118.6	173.8	0	0	0	0	0	109.5	V57 Y98	V57-A104 HydrophobicContact CG1-CB 4.05Å; V57-A104 HydrophobicContact CG2-CB 3.73Å; Y98-A104 HydrophobicContact CD1-CB 3.68Å; Y98-A104 HydrophobicContact CD2-CB 4.44Å; Y98-A104 HydrophobicContact CE1-CB 3.4Å; Y98-A104 VanDerWaalsContact CE1-CB 3.4Å; Y98-A104 HydrophobicContact CE2-CB 4.19Å; Y98-A104 HydrophobicContact CG-CB 4.19Å
105	Y	43.4	Very low	43.2	Very low	129 Å²	129	88.2 Å²	88.2	51%	0.506	47%	0.468	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.8	126.8	172.5	-62.4	-87.4	0	0	0	107.6	Y96 V97 S103 L107	Y96-Y105 CarbonylContact C-O 3.54Å; Y96-Y105 VanDerWaalsContact CA-O 3.29Å; Y96-Y105 WeakPolarHBondContact CA-O 3.31Å; V97-Y105 PolarHBondContact N-O 3.34Å; V97-Y105 PolarHBondContact O-N 2.91Å; S103-Y105 WeakPolarHBondContact OG-CE2 3.43Å; Y105-L107 PolarHBondContact O-N 3.35Å
106	K	43.8	Very low	44	Very low	106 Å²	106	94 Å²	94	46%	0.461	49%	0.487	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-60.2	114.8	162.8	-170.6	170.8	-179.9	173.3	0	105.2	Y96 Q108	Y96-K106 HydrophobicContact CD1-CB 3.7Å; Y96-K106 HydrophobicContact CD1-CG 4.05Å; Y96-K106 HydrophobicContact CE1-CB 3.49Å; Y96-K106 VanDerWaalsContact CE1-CB 3.49Å; Y96-K106 HydrophobicContact CE1-CD 4.01Å; Y96-K106 HydrophobicContact CE1-CG 3.62Å; K106-Q108 PolarHBondContact O-N 3.47Å
107	L	38.7	Very low	45	Very low	90 Å²	90	93.4 Å²	93.4	47%	0.471	49%	0.487	S	S	.	.			trans	-65.9	102.7	165	-160.5	75.1	0	0	0	102.3	C95 V97 Y105 S109	C95-L107 VanDerWaalsContact O-CB 3.26Å; C95-L107 WeakPolarHBondContact O-CB 3.43Å; C95-L107 PolarHBondContact O-N 3.29Å; V97-L107 HydrophobicContact CG2-CB 4.25Å; V97-L107 HydrophobicContact CG2-CD1 3.96Å; V97-L107 HydrophobicContact CG2-CG 4.48Å; Y105-L107 PolarHBondContact O-N 3.35Å; L107-S109 PolarHBondContact O-N 3.26Å
108	Q	36.3	Very low	46.9	Very low	149 Å²	149	93.5 Å²	93.5	70%	0.696	49%	0.488	S	S	*	.			trans	-67.6	82.6	162.8	-154	147.2	23.2	0	0	102.7	K106 Y110	K106-Q108 PolarHBondContact O-N 3.47Å; Q108-Y110 PolarHBondContact O-N 2.8Å
109	S	33.1	Very low	48.7	Very low	38 Å²	38	90.2 Å²	90.2	27%	0.266	48%	0.478	S	S	.	.			trans	-49.6	107.4	156.5	36.1	0	0	0	0	102.3	P92 L107 T111	P92-S109 PolarHBondContact O-OG 3.04Å; L107-S109 PolarHBondContact O-N 3.26Å; S109-T111 PolarHBondContact O-N 3.08Å
110	Y	37.3	Very low	50.8	Low	192 Å²	192	93.7 Å²	93.7	75%	0.753	49%	0.494	S	S	*	.			trans	-60.5	86.4	161.7	-78.3	-95.6	0	0	0	102.8	Q108 E112	Q108-Y110 PolarHBondContact O-N 2.8Å; Y110-E112 WeakPolarHBondContact O-CG 3.4Å; Y110-E112 PolarHBondContact O-N 2.93Å
111	T	34.8	Very low	53.1	Low	67 Å²	67	90.3 Å²	90.3	41%	0.411	47%	0.47	S	S	.	.			trans	-61.6	96	158.6	35.4	0	0	0	0	103.3	E93 S109 G113	E93-T111 HydrophobicContact CG-CG2 4.14Å; S109-T111 PolarHBondContact O-N 3.08Å; T111-G113 PolarHBondContact O-N 3.31Å
112	E	41.3	Very low	55.1	Low	126 Å²	126	82.6 Å²	82.6	59%	0.589	43%	0.43	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.2	24.2	-175.6	-64.8	-167.3	154.2	0	0	113.6	Y110 T182 K381	Y110-E112 WeakPolarHBondContact O-CG 3.4Å; Y110-E112 PolarHBondContact O-N 2.93Å; E112-T182 WeakPolarHBondContact OE2-CG2 3.37Å; E112-K381 WeakPolarHBondContact O-CE 3.41Å; E112-K381 IonicContact OE2-NZ 3.79Å
113	G	42.7	Very low	57.3	Low	58 Å²	58	81.2 Å²	81.2	60%	0.598	41%	0.41	S	S	*	.	T	Hydrogen-bonded Turn	trans	-128.3	-16.2	-170.5	0	0	0	0	0	116.5	T111 G115	T111-G113 PolarHBondContact O-N 3.31Å; G113-G115 PolarHBondContact O-N 3.31Å
114	Y	43.4	Very low	59.4	Low	171 Å²	171	84.1 Å²	84.1	67%	0.671	42%	0.418	S	S	*	.			trans	-96.9	95.2	177.4	-78.7	-77.2	0	0	0	111.1	K116	Y114-K116 PolarHBondContact O-N 3.44Å
115	G	55.6	Low	61.2	Low	7 Å²	7	85.1 Å²	85.1	7%	0.072	42%	0.421	C	S	.	.			trans	-53.6	128.7	172.1	0	0	0	0	0	111.5	G113 N382 K384	G113-G115 PolarHBondContact O-N 3.31Å; G115-N382 CarbonylContact C-O 3.32Å; G115-N382 VanDerWaalsContact CA-C 3.42Å; G115-N382 WeakPolarHBondContact CA-O 3.35Å; G115-K384 WeakPolarHBondContact O-CA 3.12Å; G115-K384 VanDerWaalsContact O-CB 3.22Å; G115-K384 WeakPolarHBondContact O-CB 3.21Å
116	K	68.1	Low	63.2	Low	179 Å²	179	79 Å²	79	78%	0.778	40%	0.397	S	S	*	.			trans	-81.1	-23.3	-177.9	-64.9	179.8	-179	176	0	112.3	Y114 N382	Y114-K116 PolarHBondContact O-N 3.44Å; K116-N382 PolarHBondContact N-O 3.31Å
117	N	75.2	Confident	65.4	Low	45 Å²	45	74.5 Å²	74.5	24%	0.241	38%	0.377	C	S	.	.	B	Isolated β-bridge	trans	-88	142.6	-169.4	-62.5	-16.2	0	0	0	111.1	V121 N382 N383 K384	N117-V121 HydrophobicContact CB-CB 4.42Å; N117-V121 HydrophobicContact CB-CG1 4.15Å; N117-N382 WeakPolarHBondContact CB-O 3.18Å; N117-N382 PolarHBondContact N-O 2.78Å; N117-N383 PolarHBondContact O-OD1 3.11Å; N117-K384 WeakPolarHBondContact O-CB 3.31Å; N117-K384 PolarHBondContact O-N 2.87Å
118	T	86.4	Confident	67.6	Low	78 Å²	78	70.8 Å²	70.8	48%	0.479	36%	0.357	S	S	.	.			trans	-74.1	159.3	169.2	61.1	0	0	0	0	110.3	L120 V121 T122	T118-L120 PolarHBondContact O-N 2.84Å; T118-V121 PolarHBondContact O-N 3.43Å; T118-V121 VanDerWaalsContact O-N 3.16Å; T118-V121 VanDerWaalsContact OG1-CG2 3.27Å; T118-V121 WeakPolarHBondContact OG1-CG2 3.42Å; T118-V121 PolarHBondContact OG1-N 3.39Å; T118-T122 PolarHBondContact O-N 3.39Å; T118-T122 PolarHBondContact O-OG1 2.95Å
119	S	86.9	Confident	69.9	Low	21 Å²	21	66.7 Å²	66.7	15%	0.147	34%	0.343	C	S	.	.	H	α-helix	trans	-52.7	-42.7	175.6	-76.4	0	0	0	0	112.3	T122 I123 R391 D392	S119-T122 WeakPolarHBondContact O-CB 3.49Å; S119-T122 PolarHBondContact O-N 3.26Å; S119-I123 VanDerWaalsContact O-CG1 3.3Å; S119-I123 WeakPolarHBondContact O-CG1 3.41Å; S119-I123 PolarHBondContact O-N 3.36Å; S119-R391 PolarHBondContact OG-NH2 3.12Å; S119-D392 WeakPolarHBondContact CA-OD2 3.16Å; S119-D392 WeakPolarHBondContact CB-OD2 3.2Å; S119-D392 PolarHBondContact OG-OD2 3.16Å
120	L	86.6	Confident	72.4	Confident	107 Å²	107	65.2 Å²	65.2	56%	0.56	33%	0.332	S	S	*	.	H	α-helix	trans	-63.4	-45.9	179.1	-173.9	149.1	0	0	0	111.7	T118 T122 I123 F124	T118-L120 PolarHBondContact O-N 2.84Å; L120-T122 PolarHBondContact O-N 3.02Å; L120-I123 PolarHBondContact O-N 2.86Å; L120-F124 HydrophobicContact CD1-CE2 4.49Å; L120-F124 HydrophobicContact CD2-CD2 3.47Å; L120-F124 VanDerWaalsContact CD2-CD2 3.47Å; L120-F124 HydrophobicContact CD2-CE2 3.58Å; L120-F124 HydrophobicContact CG-CD2 3.92Å; L120-F124 HydrophobicContact CG-CE2 3.87Å; L120-F124 VanDerWaalsContact O-CD2 3.32Å; L120-F124 WeakPolarHBondContact O-CD2 3.47Å; L120-F124 PolarHBondContact O-N 3.48Å
121	V	85.7	Confident	74.6	Confident	68 Å²	68	56.1 Å²	56.1	41%	0.412	30%	0.296	S	S	.	.	H	α-helix	trans	-61	-37.8	175.9	172	0	0	0	0	110.9	N117 T118 F124 M125	N117-V121 HydrophobicContact CB-CB 4.42Å; N117-V121 HydrophobicContact CB-CG1 4.15Å; T118-V121 PolarHBondContact O-N 3.43Å; T118-V121 VanDerWaalsContact O-N 3.16Å; T118-V121 VanDerWaalsContact OG1-CG2 3.27Å; T118-V121 WeakPolarHBondContact OG1-CG2 3.42Å; T118-V121 PolarHBondContact OG1-N 3.39Å; V121-F124 PolarHBondContact O-N 2.86Å; V121-M125 WeakPolarHBondContact O-CB 3.48Å; V121-M125 PolarHBondContact O-N 2.92Å
122	T	85.1	Confident	76.5	Confident	0 Å²	0	53.4 Å²	53.4	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-65.5	-43.9	177.1	-53.1	0	0	0	0	111.8	T118 S119 L120 M125 I126 L380 N383	T118-T122 PolarHBondContact O-N 3.39Å; T118-T122 PolarHBondContact O-OG1 2.95Å; S119-T122 WeakPolarHBondContact O-CB 3.49Å; S119-T122 PolarHBondContact O-N 3.26Å; L120-T122 PolarHBondContact O-N 3.02Å; T122-M125 PolarHBondContact O-N 3.3Å; T122-I126 HydrophobicContact CG2-CD1 4.22Å; T122-I126 WeakPolarHBondContact O-CG1 3.41Å; T122-I126 PolarHBondContact O-N 3.44Å; T122-L380 HydrophobicContact CG2-CD2 3.96Å; T122-N383 HydrophobicContact CG2-CB 4.32Å
123	I	90.1	Very high	78.3	Confident	22 Å²	22	48 Å²	48	11%	0.113	26%	0.257	C	S	.	.	H	α-helix	trans	-58.6	-50.9	175.1	-67.3	162.8	0	0	0	110.4	S119 L120 M125 I126 W127 D392 I395 A396	S119-I123 VanDerWaalsContact O-CG1 3.3Å; S119-I123 WeakPolarHBondContact O-CG1 3.41Å; S119-I123 PolarHBondContact O-N 3.36Å; L120-I123 PolarHBondContact O-N 2.86Å; I123-M125 VanDerWaalsContact C-N 3.3Å; I123-M125 PolarHBondContact O-N 2.9Å; I123-I126 PolarHBondContact O-N 3.2Å; I123-W127 WeakPolarHBondContact O-CB 3.42Å; I123-W127 PolarHBondContact O-N 3.21Å; I123-D392 HydrophobicContact CD1-CB 4.29Å; I123-D392 HydrophobicContact CG1-CB 3.83Å; I123-I395 HydrophobicContact CD1-CB 4.23Å; I123-I395 HydrophobicContact CD1-CD1 4.23Å; I123-I395 HydrophobicContact CD1-CG2 4.07Å; I123-I395 HydrophobicContact CG2-CG2 4Å; I123-A396 HydrophobicContact CG2-CB 4.13Å
124	F	86.3	Confident	80.3	Confident	99 Å²	99	45.8 Å²	45.8	43%	0.434	23%	0.232	S	C	.	.	H	α-helix	trans	-64.8	-34	178.4	-84.2	-73.9	0	0	0	112.6	L120 V121 W127 N128	L120-F124 HydrophobicContact CD1-CE2 4.49Å; L120-F124 HydrophobicContact CD2-CD2 3.47Å; L120-F124 VanDerWaalsContact CD2-CD2 3.47Å; L120-F124 HydrophobicContact CD2-CE2 3.58Å; L120-F124 HydrophobicContact CG-CD2 3.92Å; L120-F124 HydrophobicContact CG-CE2 3.87Å; L120-F124 VanDerWaalsContact O-CD2 3.32Å; L120-F124 WeakPolarHBondContact O-CD2 3.47Å; L120-F124 PolarHBondContact O-N 3.48Å; V121-F124 PolarHBondContact O-N 2.86Å; F124-W127 HydrophobicContact CD1-CE3 4.18Å; F124-W127 PolarHBondContact O-N 3.04Å; F124-N128 WeakPolarHBondContact O-CB 3.37Å; F124-N128 PolarHBondContact O-N 3.03Å
125	M	83.5	Confident	82.6	Confident	36 Å²	36	37.8 Å²	37.8	18%	0.177	20%	0.201	C	C	.	.	H	α-helix	trans	-66.2	-44.3	176	-174.4	179.1	64.2	0	0	111.4	V121 T122 I123 T129 L379	V121-M125 WeakPolarHBondContact O-CB 3.48Å; V121-M125 PolarHBondContact O-N 2.92Å; T122-M125 PolarHBondContact O-N 3.3Å; I123-M125 VanDerWaalsContact C-N 3.3Å; I123-M125 PolarHBondContact O-N 2.9Å; M125-T129 WeakPolarHBondContact O-CB 3.35Å; M125-T129 PolarHBondContact O-N 3.46Å; M125-T129 PolarHBondContact O-OG1 3.15Å; M125-L379 HydrophobicContact CE-CB 3.81Å; M125-L379 HydrophobicContact CE-CD2 3.44Å; M125-L379 VanDerWaalsContact CE-CD2 3.44Å; M125-L379 HydrophobicContact CE-CG 4.17Å; M125-L379 HydrophobicContact CG-CD2 4.17Å; M125-L379 HydrophobicContact SD-CD2 3.74Å
126	I	87.3	Confident	84.4	Confident	0 Å²	0	37.5 Å²	37.5	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-62.1	-48.6	174.5	-69.2	167.9	0	0	0	110	T122 I123 N128 T129 M130 I372 I376 L380 L393 A396	T122-I126 HydrophobicContact CG2-CD1 4.22Å; T122-I126 WeakPolarHBondContact O-CG1 3.41Å; T122-I126 PolarHBondContact O-N 3.44Å; I123-I126 PolarHBondContact O-N 3.2Å; I126-N128 PolarHBondContact O-N 3.47Å; I126-T129 PolarHBondContact O-N 3.06Å; I126-M130 HydrophobicContact CG2-CE 3.91Å; I126-M130 PolarHBondContact O-N 3.34Å; I126-M130 VanDerWaalsContact O-N 3.13Å; I126-I372 HydrophobicContact CB-CD1 4.23Å; I126-I372 HydrophobicContact CG1-CD1 4.25Å; I126-I372 HydrophobicContact CG2-CD1 3.77Å; I126-I376 HydrophobicContact CD1-CD1 3.75Å; I126-I376 HydrophobicContact CG1-CD1 4.06Å; I126-L380 HydrophobicContact CD1-CD2 4.04Å; I126-L393 HydrophobicContact CD1-CD1 4.45Å; I126-A396 HydrophobicContact CB-CB 3.82Å; I126-A396 HydrophobicContact CD1-CB 4.41Å; I126-A396 HydrophobicContact CG2-CB 3.49Å; I126-A396 VanDerWaalsContact CG2-CB 3.49Å
127	W	90.1	Very high	85.5	Confident	12 Å²	12	29 Å²	29	5%	0.045	16%	0.161	C	C	.	.	H	α-helix	trans	-57.6	-51	177.8	175.9	81.1	0	0	0	111.5	I123 F124 T129 M130 M131 T319 V322 L399 V400 T403	I123-W127 WeakPolarHBondContact O-CB 3.42Å; I123-W127 PolarHBondContact O-N 3.21Å; F124-W127 HydrophobicContact CD1-CE3 4.18Å; F124-W127 PolarHBondContact O-N 3.04Å; W127-T129 VanDerWaalsContact C-N 3.26Å; W127-T129 PolarHBondContact O-N 3.23Å; W127-M130 PolarHBondContact O-N 2.92Å; W127-M131 HydrophobicContact CD2-CG 3.7Å; W127-M131 HydrophobicContact CE3-CG 4.26Å; W127-M131 HydrophobicContact CG-CG 4.07Å; W127-M131 HydrophobicContact CH2-CG 4.27Å; W127-M131 HydrophobicContact CZ2-CG 3.71Å; W127-M131 HydrophobicContact CZ2-SD 4.21Å; W127-M131 WeakPolarHBondContact O-CB 3.18Å; W127-M131 WeakPolarHBondContact O-CG 3.38Å; W127-M131 PolarHBondContact O-N 3.4Å; W127-T319 HydrophobicContact CZ3-CG2 4.16Å; W127-V322 HydrophobicContact CH2-CB 4.15Å; W127-V322 HydrophobicContact CH2-CG1 3.56Å; W127-V322 HydrophobicContact CZ2-CG1 3.76Å; W127-L399 HydrophobicContact CB-CD2 4.13Å; W127-L399 VanDerWaalsContact CD1-CG 3.49Å; W127-L399 HydrophobicContact CD2-CD2 4.17Å; W127-L399 HydrophobicContact CG-CD2 3.68Å; W127-L399 HydrophobicContact CG-CG 4.16Å; W127-V400 HydrophobicContact CB-CG2 4.31Å; W127-V400 HydrophobicContact CG-CG2 4.25Å; W127-T403 HydrophobicContact CZ2-CG2 4.15Å
128	N	84.5	Confident	86.5	Confident	11 Å²	11	26.9 Å²	26.9	6%	0.059	15%	0.149	C	C	.	.	H	α-helix	trans	-65.2	-27.9	179.8	-166.9	56.4	0	0	0	113	F124 I126 N315 T319	F124-N128 WeakPolarHBondContact O-CB 3.37Å; F124-N128 PolarHBondContact O-N 3.03Å; I126-N128 PolarHBondContact O-N 3.47Å; N128-N315 PolarHBondContact ND2-O 3.49Å; N128-N315 VanDerWaalsContact ND2-O 3.14Å; N128-N315 PolarHBondContact ND2-OD1 2.98Å; N128-T319 VanDerWaalsContact CG-OG1 3.28Å; N128-T319 WeakPolarHBondContact OD1-CA 3.34Å; N128-T319 PolarHBondContact OD1-N 3.48Å; N128-T319 VanDerWaalsContact OD1-N 3.15Å; N128-T319 PolarHBondContact OD1-OG1 3.32Å
129	T	83.2	Confident	86.9	Confident	64 Å²	64	23.1 Å²	23.1	39%	0.393	13%	0.127	S	C	.	.	H	α-helix	trans	-72.7	-35.4	176.3	-56.7	0	0	0	0	111.6	M125 I126 W127 I372	M125-T129 WeakPolarHBondContact O-CB 3.35Å; M125-T129 PolarHBondContact O-N 3.46Å; M125-T129 PolarHBondContact O-OG1 3.15Å; I126-T129 PolarHBondContact O-N 3.06Å; W127-T129 VanDerWaalsContact C-N 3.26Å; W127-T129 PolarHBondContact O-N 3.23Å; T129-I372 HydrophobicContact CG2-CD1 4.2Å; T129-I372 HydrophobicContact CG2-CG1 4.46Å
130	M	86.7	Confident	87.2	Confident	7 Å²	7	22.9 Å²	22.9	3%	0.034	12%	0.122	C	C	.	.	H	α-helix	trans	-82	-31.6	174.4	-65.9	-178.2	-171.7	0	0	112.7	I126 W127 G132 I372 Y397 V400 Y404	I126-M130 HydrophobicContact CG2-CE 3.91Å; I126-M130 PolarHBondContact O-N 3.34Å; I126-M130 VanDerWaalsContact O-N 3.13Å; W127-M130 PolarHBondContact O-N 2.92Å; M130-G132 PolarHBondContact O-N 2.85Å; M130-I372 HydrophobicContact CE-CB 3.52Å; M130-I372 HydrophobicContact CE-CD1 3.96Å; M130-I372 HydrophobicContact CE-CG1 4.34Å; M130-I372 HydrophobicContact CE-CG2 3.17Å; M130-I372 HydrophobicContact CG-CB 4.45Å; M130-I372 HydrophobicContact CG-CD1 4.4Å; M130-Y397 HydrophobicContact CE-CD2 4.01Å; M130-Y397 HydrophobicContact CE-CE1 4.06Å; M130-Y397 HydrophobicContact CE-CE2 3.41Å; M130-Y397 VanDerWaalsContact CE-CE2 3.41Å; M130-Y397 VanDerWaalsContact CE-CZ 3.44Å; M130-V400 HydrophobicContact CB-CG1 4.16Å; M130-V400 HydrophobicContact CB-CG2 4.01Å; M130-V400 HydrophobicContact CG-CG2 4.46Å; M130-V400 HydrophobicContact SD-CB 4.22Å; M130-V400 HydrophobicContact SD-CG1 3.93Å; M130-V400 HydrophobicContact SD-CG2 3.72Å; M130-Y404 PolarHBondContact O-OH 3.01Å
131	M	83.5	Confident	87.6	Confident	1 Å²	1	17.8 Å²	17.8	1%	0.005	10%	0.096	C	C	.	.			trans	-71.5	90.2	174.9	-69.8	-62.8	123.7	0	0	110.2	W127 I135 V322 V400 T403 Y404	W127-M131 HydrophobicContact CD2-CG 3.7Å; W127-M131 HydrophobicContact CE3-CG 4.26Å; W127-M131 HydrophobicContact CG-CG 4.07Å; W127-M131 HydrophobicContact CH2-CG 4.27Å; W127-M131 HydrophobicContact CZ2-CG 3.71Å; W127-M131 HydrophobicContact CZ2-SD 4.21Å; W127-M131 WeakPolarHBondContact O-CB 3.18Å; W127-M131 WeakPolarHBondContact O-CG 3.38Å; W127-M131 PolarHBondContact O-N 3.4Å; M131-I135 HydrophobicContact SD-CD1 3.72Å; M131-V322 HydrophobicContact CB-CG1 4.22Å; M131-V322 HydrophobicContact CB-CG2 3.79Å; M131-V322 HydrophobicContact CG-CG1 4.18Å; M131-V322 HydrophobicContact SD-CG1 4.28Å; M131-V400 HydrophobicContact CE-CB 3.81Å; M131-V400 HydrophobicContact CE-CG1 3.57Å; M131-V400 HydrophobicContact CE-CG2 3.75Å; M131-T403 WeakPolarHBondContact CE-OG1 3.41Å; M131-Y404 HydrophobicContact CE-CD1 3.91Å; M131-Y404 HydrophobicContact CE-CE1 3.46Å; M131-Y404 VanDerWaalsContact CE-CE1 3.46Å; M131-Y404 HydrophobicContact SD-CD1 4.41Å; M131-Y404 HydrophobicContact SD-CE1 3.93Å
132	G	74.1	Confident	88.1	Confident	9 Å²	9	14.5 Å²	14.5	9%	0.093	8%	0.076	C	C	.	.	S	Bend	trans	-137.5	-147.8	176.9	0	0	0	0	0	112.1	M130 S134 I135	M130-G132 PolarHBondContact O-N 2.85Å; G132-S134 PolarHBondContact O-N 2.92Å; G132-S134 VanDerWaalsContact O-N 3.15Å; G132-I135 WeakPolarHBondContact O-CG2 3.5Å; G132-I135 PolarHBondContact O-N 2.83Å
133	T	79.1	Confident	88.5	Confident	13 Å²	13	15.5 Å²	15.5	8%	0.08	8%	0.08	C	C	.	.	G	3₁₀ helix	trans	-55.5	-27.8	178.5	50.8	0	0	0	0	114.3	I135 L136 Y216 L219 M451	T133-I135 PolarHBondContact O-N 3.28Å; T133-L136 WeakPolarHBondContact O-CB 3.18Å; T133-L136 PolarHBondContact O-N 3.23Å; T133-L136 VanDerWaalsContact O-N 3.14Å; T133-Y216 HydrophobicContact CG2-CD1 3.63Å; T133-Y216 HydrophobicContact CG2-CE1 3.43Å; T133-Y216 VanDerWaalsContact CG2-CE1 3.43Å; T133-Y216 HydrophobicContact CG2-CG 4.43Å; T133-Y216 WeakPolarHBondContact OG1-CE1 3.45Å; T133-L219 HydrophobicContact CG2-CD1 3.27Å; T133-M451 HydrophobicContact CG2-CE 3.25Å; T133-M451 HydrophobicContact CG2-CG 4.24Å; T133-M451 HydrophobicContact CG2-SD 3.59Å; T133-M451 VanDerWaalsContact CG2-SD 3.59Å
134	S	84.9	Confident	88.6	Confident	12 Å²	12	15.6 Å²	15.6	8%	0.084	8%	0.08	C	C	.	.	G	3₁₀ helix	trans	-56.8	-31.9	-179.6	51.8	0	0	0	0	113.2	G132 L136 S137 Y404	G132-S134 PolarHBondContact O-N 2.92Å; G132-S134 VanDerWaalsContact O-N 3.15Å; S134-L136 PolarHBondContact O-N 2.88Å; S134-S137 PolarHBondContact O-N 3.43Å; S134-S137 VanDerWaalsContact O-N 3.16Å; S134-Y404 PolarHBondContact OG-OH 3.45Å
135	I	91.8	Very high	88.9	Confident	3 Å²	3	10.9 Å²	10.9	2%	0.015	6%	0.06	C	C	.	.	G	3₁₀ helix	trans	-62.2	-29	-179.2	-154	164.1	0	0	0	112.7	M131 G132 T133 S137 L325 Y404 I407	M131-I135 HydrophobicContact SD-CD1 3.72Å; G132-I135 WeakPolarHBondContact O-CG2 3.5Å; G132-I135 PolarHBondContact O-N 2.83Å; T133-I135 PolarHBondContact O-N 3.28Å; I135-S137 VanDerWaalsContact C-N 3.26Å; I135-S137 PolarHBondContact O-N 3.34Å; I135-L325 HydrophobicContact CD1-CD2 4.44Å; I135-L325 HydrophobicContact CG2-CD2 3.45Å; I135-L325 VanDerWaalsContact CG2-CD2 3.45Å; I135-Y404 HydrophobicContact CB-CE1 4.22Å; I135-Y404 HydrophobicContact CD1-CD1 4.32Å; I135-Y404 HydrophobicContact CD1-CE1 4.36Å; I135-Y404 HydrophobicContact CG1-CD1 3.98Å; I135-Y404 HydrophobicContact CG1-CE1 4.13Å; I135-I407 HydrophobicContact CD1-CD1 3.21Å; I135-I407 HydrophobicContact CG1-CB 4.47Å; I135-I407 HydrophobicContact CG1-CD1 3.6Å; I135-I407 HydrophobicContact CG1-CG2 4.36Å
136	L	92.5	Very high	89.4	Confident	0 Å²	0	9.2 Å²	9.2	0%	0	5%	0.051	C	C	.	.	G	3₁₀ helix	trans	-72.6	-21.5	-178.3	-58.5	169.6	0	0	0	112.5	T133 S134 L219 F223 L325 Q427 F429 L430 L447	T133-L136 WeakPolarHBondContact O-CB 3.18Å; T133-L136 PolarHBondContact O-N 3.23Å; T133-L136 VanDerWaalsContact O-N 3.14Å; S134-L136 PolarHBondContact O-N 2.88Å; L136-L219 HydrophobicContact CD1-CD2 4.23Å; L136-F223 HydrophobicContact CD1-CE2 4.4Å; L136-F223 HydrophobicContact CD1-CZ 3.68Å; L136-L325 HydrophobicContact CD2-CD1 4.35Å; L136-L325 HydrophobicContact CD2-CD2 4.13Å; L136-Q427 CarbonylContact C-O 3.3Å; L136-F429 HydrophobicContact CB-CD1 4.47Å; L136-F429 HydrophobicContact CD2-CD1 4.32Å; L136-F429 HydrophobicContact CD2-CE1 3.76Å; L136-F429 HydrophobicContact CD2-CZ 4.22Å; L136-F429 WeakPolarHBondContact O-CD1 3.49Å; L136-F429 PolarHBondContact O-N 3.31Å; L136-L430 HydrophobicContact CD2-CD1 3.83Å; L136-L430 HydrophobicContact CD2-CG 4.06Å; L136-L447 HydrophobicContact CD1-CD1 4.39Å; L136-L447 HydrophobicContact CD2-CD1 4.07Å
137	S	92.9	Very high	89.7	Confident	1 Å²	1	10.5 Å²	10.5	1%	0.007	6%	0.057	C	C	.	.	G	3₁₀ helix	trans	-103.1	-4.8	-176.6	-55.6	0	0	0	0	114	S134 I135 W140 G141 Q427	S134-S137 PolarHBondContact O-N 3.43Å; S134-S137 VanDerWaalsContact O-N 3.16Å; I135-S137 VanDerWaalsContact C-N 3.26Å; I135-S137 PolarHBondContact O-N 3.34Å; S137-W140 PolarHBondContact O-N 2.97Å; S137-G141 PolarHBondContact O-N 3.27Å; S137-Q427 WeakPolarHBondContact CA-O 3.18Å; S137-Q427 VanDerWaalsContact CB-O 3.29Å; S137-Q427 WeakPolarHBondContact CB-O 3.43Å; S137-Q427 PolarHBondContact OG-O 3.39Å
138	I	94.8	Very high	89.9	Confident	0 Å²	0	12.2 Å²	12.2	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-61.5	-46.3	177.8	-57	-60.2	0	0	0	112.4	W140 G141 I142 I154 L366 Y404	I138-W140 VanDerWaalsContact C-N 3.29Å; I138-W140 PolarHBondContact O-N 3.46Å; I138-G141 PolarHBondContact O-N 3.28Å; I138-I142 HydrophobicContact CG2-CD1 4.18Å; I138-I142 HydrophobicContact CG2-CG1 4.48Å; I138-I142 WeakPolarHBondContact O-CG1 3.21Å; I138-I142 PolarHBondContact O-N 3.16Å; I138-I154 HydrophobicContact CG2-CD1 3.93Å; I138-L366 HydrophobicContact CD1-CD2 3.73Å; I138-Y404 HydrophobicContact CD1-CG 4.4Å; I138-Y404 HydrophobicContact CG1-CD1 4.33Å; I138-Y404 HydrophobicContact CG1-CG 4.32Å
139	P	95.1	Very high	90.3	Very high	0 Å²	0	13 Å²	13	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-60.9	-39.1	178.9	-22.9	34.7	0	0	0	112.6	I142 K143 V411 I425 F429	P139-I142 PolarHBondContact O-N 3.15Å; P139-K143 PolarHBondContact O-N 3.36Å; P139-V411 HydrophobicContact CB-CB 3.89Å; P139-V411 HydrophobicContact CB-CG1 3.62Å; P139-V411 HydrophobicContact CG-CB 3.62Å; P139-V411 HydrophobicContact CG-CG1 3.67Å; P139-V411 HydrophobicContact CG-CG2 4.06Å; P139-I425 HydrophobicContact CB-CG2 4.09Å; P139-F429 HydrophobicContact CG-CB 4.28Å; P139-F429 HydrophobicContact CG-CD1 3.96Å; P139-F429 HydrophobicContact CG-CG 4.34Å
140	W	94.6	Very high	90.9	Very high	15 Å²	15	10 Å²	10	6%	0.057	6%	0.055	C	C	.	.	H	α-helix	trans	-64.2	-40.7	173	174.8	89.4	0	0	0	112.3	S137 I138 I142 K143 Q144 Q361 V365 I425 E426 Q427	S137-W140 PolarHBondContact O-N 2.97Å; I138-W140 VanDerWaalsContact C-N 3.29Å; I138-W140 PolarHBondContact O-N 3.46Å; W140-I142 VanDerWaalsContact C-N 3.34Å; W140-I142 PolarHBondContact O-N 3.31Å; W140-K143 VanDerWaalsContact O-CB 3.31Å; W140-K143 WeakPolarHBondContact O-CB 3.28Å; W140-K143 PolarHBondContact O-N 3.05Å; W140-Q144 HydrophobicContact CD2-CG 4.1Å; W140-Q144 HydrophobicContact CE3-CG 4.34Å; W140-Q144 HydrophobicContact CH2-CG 3.99Å; W140-Q144 HydrophobicContact CZ2-CG 3.73Å; W140-Q144 HydrophobicContact CZ3-CG 4.29Å; W140-Q144 WeakPolarHBondContact O-CG 3.18Å; W140-Q144 PolarHBondContact O-N 3.31Å; W140-Q361 HydrophobicContact CH2-CB 4.42Å; W140-V365 HydrophobicContact CZ3-CG2 4.02Å; W140-I425 HydrophobicContact CB-CG2 4.46Å; W140-E426 WeakPolarHBondContact CB-O 3.34Å; W140-Q427 HydrophobicContact CD2-CB 4.49Å; W140-Q427 HydrophobicContact CD2-CG 3.83Å; W140-Q427 HydrophobicContact CG-CB 4.32Å; W140-Q427 HydrophobicContact CG-CG 3.9Å; W140-Q427 HydrophobicContact CZ2-CG 4.18Å
141	G	94.1	Very high	91.3	Very high	0 Å²	0	11.8 Å²	11.8	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-62.6	-40.5	175.2	0	0	0	0	0	112.4	S137 I138 K143 Q144 A145	S137-G141 PolarHBondContact O-N 3.27Å; I138-G141 PolarHBondContact O-N 3.28Å; G141-K143 VanDerWaalsContact C-N 3.33Å; G141-K143 PolarHBondContact O-N 3.02Å; G141-Q144 PolarHBondContact O-N 3.49Å; G141-A145 PolarHBondContact O-N 3.14Å
142	I	95.4	Very high	91.9	Very high	0 Å²	0	15 Å²	15	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-61.7	-42.6	173.5	-66	172.6	0	0	0	110.4	I138 P139 W140 Q144 A145 G146 F147 I154 F412	I138-I142 HydrophobicContact CG2-CD1 4.18Å; I138-I142 HydrophobicContact CG2-CG1 4.48Å; I138-I142 WeakPolarHBondContact O-CG1 3.21Å; I138-I142 PolarHBondContact O-N 3.16Å; P139-I142 PolarHBondContact O-N 3.15Å; W140-I142 VanDerWaalsContact C-N 3.34Å; W140-I142 PolarHBondContact O-N 3.31Å; I142-Q144 VanDerWaalsContact C-N 3.3Å; I142-Q144 PolarHBondContact O-N 3.2Å; I142-A145 PolarHBondContact O-N 3.2Å; I142-G146 CarbonylContact O-C 3.49Å; I142-G146 VanDerWaalsContact O-C 3.3Å; I142-G146 WeakPolarHBondContact O-CA 3.41Å; I142-G146 PolarHBondContact O-N 3.3Å; I142-F147 HydrophobicContact CG2-CB 4.48Å; I142-F147 HydrophobicContact CG2-CD2 4.15Å; I142-I154 HydrophobicContact CD1-CD1 3.85Å; I142-I154 HydrophobicContact CG1-CD1 3.86Å; I142-F412 HydrophobicContact CB-CD2 4.49Å; I142-F412 HydrophobicContact CG2-CD2 3.91Å; I142-F412 HydrophobicContact CG2-CE2 4.29Å; I142-F412 HydrophobicContact CG2-CG 4.13Å
143	K	93.8	Very high	93	Very high	20 Å²	20	15.3 Å²	15.3	9%	0.087	9%	0.086	C	C	.	.	H	α-helix	trans	-57.1	-40.5	173.6	178.3	-160.2	102.5	168.4	0	112.9	P139 W140 G141 R356 F412 K422 D423 I425	P139-K143 PolarHBondContact O-N 3.36Å; W140-K143 VanDerWaalsContact O-CB 3.31Å; W140-K143 WeakPolarHBondContact O-CB 3.28Å; W140-K143 PolarHBondContact O-N 3.05Å; G141-K143 VanDerWaalsContact C-N 3.33Å; G141-K143 PolarHBondContact O-N 3.02Å; K143-R356 VanDerWaalsContact O-CD 3.25Å; K143-R356 WeakPolarHBondContact O-CD 3.3Å; K143-R356 PolarHBondContact O-NH1 2.82Å; K143-F412 HydrophobicContact CB-CE2 4.34Å; K143-K422 WeakPolarHBondContact CD-O 3.45Å; K143-D423 PolarHBondContact NZ-O 2.93Å; K143-I425 HydrophobicContact CD-CB 3.88Å; K143-I425 PolarHBondContact NZ-O 3.44Å
144	Q	92.8	Very high	93.8	Very high	25 Å²	25	14.7 Å²	14.7	12%	0.117	8%	0.082	C	C	.	.	H	α-helix	trans	-71.7	-32.9	178.5	-63.5	-61.5	-7.1	0	0	113	W140 G141 I142 R356 Q358 Q361	W140-Q144 HydrophobicContact CD2-CG 4.1Å; W140-Q144 HydrophobicContact CE3-CG 4.34Å; W140-Q144 HydrophobicContact CH2-CG 3.99Å; W140-Q144 HydrophobicContact CZ2-CG 3.73Å; W140-Q144 HydrophobicContact CZ3-CG 4.29Å; W140-Q144 WeakPolarHBondContact O-CG 3.18Å; W140-Q144 PolarHBondContact O-N 3.31Å; G141-Q144 PolarHBondContact O-N 3.49Å; I142-Q144 VanDerWaalsContact C-N 3.3Å; I142-Q144 PolarHBondContact O-N 3.2Å; Q144-R356 WeakPolarHBondContact O-CB 3.5Å; Q144-R356 WeakPolarHBondContact O-CD 3.41Å; Q144-Q358 HydrophobicContact CB-CB 4.42Å; Q144-Q358 CarbonylContact O-C 3.59Å; Q144-Q358 WeakPolarHBondContact O-CB 3.46Å; Q144-Q361 HydrophobicContact CB-CB 4.34Å; Q144-Q361 VanDerWaalsContact CD-OE1 3.3Å
145	A	93.4	Very high	94.4	Very high	0 Å²	0	17.8 Å²	17.8	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-84.7	-24.6	178.1	0	0	0	0	0	113.9	G141 I142 T149 R356 F359 L362	G141-A145 PolarHBondContact O-N 3.14Å; I142-A145 PolarHBondContact O-N 3.2Å; A145-T149 HydrophobicContact CB-CG2 4.49Å; A145-T149 WeakPolarHBondContact O-CB 3.18Å; A145-R356 WeakPolarHBondContact O-CB 3.41Å; A145-R356 PolarHBondContact O-N 3.45Å; A145-F359 HydrophobicContact CB-CB 3.72Å; A145-L362 HydrophobicContact CB-CB 4.28Å; A145-L362 HydrophobicContact CB-CD2 3.73Å
146	G	93.5	Very high	94.6	Very high	0 Å²	0	23 Å²	23	0%	0	13%	0.125	C	C	.	.			trans	88.6	153.9	-160.3	0	0	0	0	0	110.7	I142 G150 P353 E354	I142-G146 CarbonylContact O-C 3.49Å; I142-G146 VanDerWaalsContact O-C 3.3Å; I142-G146 WeakPolarHBondContact O-CA 3.41Å; I142-G146 PolarHBondContact O-N 3.3Å; G146-G150 WeakPolarHBondContact O-CA 3.49Å; G146-G150 PolarHBondContact O-N 3.29Å; G146-P353 WeakPolarHBondContact CA-O 3.22Å; G146-E354 CarbonylContact C-O 3.45Å; G146-E354 WeakPolarHBondContact CA-O 3.41Å
147	F	93.9	Very high	94.8	Very high	27 Å²	27	23.8 Å²	23.8	12%	0.118	13%	0.128	C	C	.	.	H	α-helix	trans	-64	-56.4	-168.7	175.8	-105.4	0	0	0	112.9	I142 T149 G150 M151 F342 E354 V409 F412	I142-F147 HydrophobicContact CG2-CB 4.48Å; I142-F147 HydrophobicContact CG2-CD2 4.15Å; F147-T149 PolarHBondContact O-N 2.94Å; F147-G150 PolarHBondContact O-N 2.69Å; F147-M151 VanDerWaalsContact O-CG 3.3Å; F147-M151 WeakPolarHBondContact O-CG 3.09Å; F147-M151 PolarHBondContact O-N 2.98Å; F147-F342 AromaticContact CD1-CE1 3.91Å; F147-F342 HydrophobicContact CD1-CE1 3.91Å; F147-F342 AromaticContact CE1-CE1 3.97Å; F147-F342 HydrophobicContact CE1-CE1 3.97Å; F147-E354 WeakPolarHBondContact CB-OE2 3.08Å; F147-V409 HydrophobicContact CE2-CG1 4.28Å; F147-V409 HydrophobicContact CE2-CG2 4.29Å; F147-V409 HydrophobicContact CZ-CG1 4.35Å; F147-F412 HydrophobicContact CB-CD1 4.15Å; F147-F412 HydrophobicContact CB-CE1 3.56Å; F147-F412 HydrophobicContact CB-CZ 3.92Å; F147-F412 AromaticContact CD2-CD1 3.34Å; F147-F412 HydrophobicContact CD2-CD1 3.34Å; F147-F412 AromaticContact CD2-CE1 3.67Å; F147-F412 HydrophobicContact CD2-CE1 3.67Å; F147-F412 HydrophobicContact CD2-CG 4.07Å; F147-F412 HydrophobicContact CE2-CD1 4.01Å; F147-F412 HydrophobicContact CG-CD1 4.02Å; F147-F412 AromaticContact CG-CE1 3.85Å; F147-F412 HydrophobicContact CG-CE1 3.85Å
148	T	93.3	Very high	94.9	Very high	49 Å²	49	23.9 Å²	23.9	30%	0.301	13%	0.129	S	C	.	.	H	α-helix	trans	-61.1	-47.4	179.2	-60.1	0	0	0	0	111.7	G150 M151 C152 E354	T148-G150 PolarHBondContact O-N 3.03Å; T148-M151 PolarHBondContact O-N 2.98Å; T148-C152 PolarHBondContact O-N 2.84Å; T148-C152 VanDerWaalsContact O-N 3.14Å; T148-C152 PolarHBondContact O-SG 3.03Å; T148-E354 VanDerWaalsContact CB-OE2 3.29Å; T148-E354 WeakPolarHBondContact CB-OE2 3.33Å; T148-E354 PolarHBondContact N-OE2 2.79Å; T148-E354 PolarHBondContact OG1-OE2 2.84Å
149	T	93.9	Very high	95	Very high	27 Å²	27	28.5 Å²	28.5	17%	0.166	15%	0.154	C	C	.	.	H	α-helix	trans	-63.9	-42.4	179.4	-54	0	0	0	0	111.3	A145 F147 M151 C152 V153 E354 F359	A145-T149 HydrophobicContact CB-CG2 4.49Å; A145-T149 WeakPolarHBondContact O-CB 3.18Å; F147-T149 PolarHBondContact O-N 2.94Å; T149-M151 VanDerWaalsContact C-N 3.34Å; T149-M151 PolarHBondContact O-N 3.31Å; T149-C152 PolarHBondContact O-N 2.96Å; T149-V153 HydrophobicContact CG2-CG2 4.19Å; T149-V153 WeakPolarHBondContact O-CB 3.41Å; T149-V153 VanDerWaalsContact O-CG2 3.23Å; T149-V153 WeakPolarHBondContact O-CG2 3.26Å; T149-V153 PolarHBondContact O-N 2.86Å; T149-E354 PolarHBondContact N-O 2.83Å; T149-E354 PolarHBondContact OG1-O 2.72Å; T149-F359 HydrophobicContact CG2-CB 4.03Å; T149-F359 HydrophobicContact CG2-CG 4.47Å
150	G	95.3	Very high	95	Very high	0 Å²	0	30 Å²	30	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-60.6	-42.2	178.3	0	0	0	0	0	112.5	G146 F147 T148 V153 I154	G146-G150 WeakPolarHBondContact O-CA 3.49Å; G146-G150 PolarHBondContact O-N 3.29Å; F147-G150 PolarHBondContact O-N 2.69Å; T148-G150 PolarHBondContact O-N 3.03Å; G150-V153 PolarHBondContact O-N 3.47Å; G150-I154 VanDerWaalsContact O-CG1 3.27Å; G150-I154 WeakPolarHBondContact O-CG1 3.45Å; G150-I154 PolarHBondContact O-N 3.21Å
151	M	95.6	Very high	95	Very high	46 Å²	46	29.3 Å²	29.3	23%	0.227	16%	0.159	C	C	.	.	H	α-helix	trans	-61.3	-47.8	174.9	-71	-60.9	-74.5	0	0	112.3	F147 T148 T149 V153 I154 I155 L405 V409	F147-M151 VanDerWaalsContact O-CG 3.3Å; F147-M151 WeakPolarHBondContact O-CG 3.09Å; F147-M151 PolarHBondContact O-N 2.98Å; T148-M151 PolarHBondContact O-N 2.98Å; T149-M151 VanDerWaalsContact C-N 3.34Å; T149-M151 PolarHBondContact O-N 3.31Å; M151-V153 VanDerWaalsContact C-N 3.34Å; M151-V153 PolarHBondContact O-N 3.15Å; M151-I154 PolarHBondContact O-N 3.19Å; M151-I155 WeakPolarHBondContact O-CG1 3.4Å; M151-I155 PolarHBondContact O-N 3.18Å; M151-L405 HydrophobicContact CE-CB 4.46Å; M151-L405 HydrophobicContact CE-CD2 3.54Å; M151-L405 HydrophobicContact CE-CG 4.47Å; M151-L405 HydrophobicContact SD-CD2 3.57Å; M151-L405 VanDerWaalsContact SD-CD2 3.57Å; M151-V409 HydrophobicContact CE-CG2 3.31Å; M151-V409 HydrophobicContact CG-CG2 4.44Å; M151-V409 HydrophobicContact SD-CG2 3.2Å; M151-V409 WeakPolarHBondContact SD-CG2 3.2Å
152	C	96.1	Very high	95.1	Very high	67 Å²	67	30.5 Å²	30.5	45%	0.453	17%	0.165	S	C	.	.	H	α-helix	trans	-60.3	-44.2	175.6	-68.4	0	0	0	0	111.6	T148 T149 I155 L156	T148-C152 PolarHBondContact O-N 2.84Å; T148-C152 VanDerWaalsContact O-N 3.14Å; T148-C152 PolarHBondContact O-SG 3.03Å; T149-C152 PolarHBondContact O-N 2.96Å; C152-I155 PolarHBondContact O-N 2.95Å; C152-L156 WeakPolarHBondContact O-CB 3.43Å; C152-L156 VanDerWaalsContact O-CG 3.26Å; C152-L156 WeakPolarHBondContact O-CG 3.4Å; C152-L156 PolarHBondContact O-N 3.04Å
153	V	96.3	Very high	95.1	Very high	16 Å²	16	33.2 Å²	33.2	10%	0.097	18%	0.176	C	C	.	.	H	α-helix	trans	-64.4	-41.1	-179.6	169.1	0	0	0	0	111.7	T149 G150 M151 I155 L156 M157 F359 L362 T363 L366	T149-V153 HydrophobicContact CG2-CG2 4.19Å; T149-V153 WeakPolarHBondContact O-CB 3.41Å; T149-V153 VanDerWaalsContact O-CG2 3.23Å; T149-V153 WeakPolarHBondContact O-CG2 3.26Å; T149-V153 PolarHBondContact O-N 2.86Å; G150-V153 PolarHBondContact O-N 3.47Å; M151-V153 VanDerWaalsContact C-N 3.34Å; M151-V153 PolarHBondContact O-N 3.15Å; V153-I155 PolarHBondContact O-N 3.25Å; V153-L156 PolarHBondContact O-N 3.13Å; V153-M157 HydrophobicContact CG1-CG 4.06Å; V153-M157 VanDerWaalsContact O-CB 3.22Å; V153-M157 WeakPolarHBondContact O-CB 3.31Å; V153-M157 VanDerWaalsContact O-CG 3.26Å; V153-M157 WeakPolarHBondContact O-CG 3.47Å; V153-M157 PolarHBondContact O-N 3.29Å; V153-F359 HydrophobicContact CG2-CD2 4.37Å; V153-L362 HydrophobicContact CB-CD2 3.98Å; V153-L362 HydrophobicContact CG1-CD2 3.82Å; V153-L362 HydrophobicContact CG1-CG 4.02Å; V153-T363 HydrophobicContact CG1-CG2 3.63Å; V153-L366 HydrophobicContact CG1-CD1 3.8Å
154	I	96.8	Very high	95.2	Very high	0 Å²	0	32.2 Å²	32.2	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-60.4	-45.5	176.3	-67.9	164.9	0	0	0	111	I138 I142 G150 M151 G158 L362 L366 T401 L405	I138-I154 HydrophobicContact CG2-CD1 3.93Å; I142-I154 HydrophobicContact CD1-CD1 3.85Å; I142-I154 HydrophobicContact CG1-CD1 3.86Å; G150-I154 VanDerWaalsContact O-CG1 3.27Å; G150-I154 WeakPolarHBondContact O-CG1 3.45Å; G150-I154 PolarHBondContact O-N 3.21Å; M151-I154 PolarHBondContact O-N 3.19Å; I154-G158 PolarHBondContact O-N 3.45Å; I154-L362 HydrophobicContact CG1-CD2 4.46Å; I154-L366 HydrophobicContact CB-CD1 4.35Å; I154-L366 HydrophobicContact CG1-CD1 3.8Å; I154-L366 HydrophobicContact CG1-CD2 3.95Å; I154-L366 HydrophobicContact CG1-CG 4.48Å; I154-T401 HydrophobicContact CG2-CG2 4.27Å; I154-L405 HydrophobicContact CB-CD2 3.71Å; I154-L405 HydrophobicContact CB-CG 4.5Å; I154-L405 HydrophobicContact CD1-CD2 4.05Å; I154-L405 HydrophobicContact CG1-CD2 4.49Å; I154-L405 HydrophobicContact CG2-CD2 3.47Å; I154-L405 VanDerWaalsContact CG2-CD2 3.47Å; I154-L405 HydrophobicContact CG2-CG 3.72Å
155	I	96.9	Very high	95.2	Very high	78 Å²	78	31 Å²	31	40%	0.4	17%	0.166	S	C	.	.	H	α-helix	trans	-65.3	-48.4	179	-65.7	169	0	0	0	110.8	M151 C152 V153 G158 L159 L405	M151-I155 WeakPolarHBondContact O-CG1 3.4Å; M151-I155 PolarHBondContact O-N 3.18Å; C152-I155 PolarHBondContact O-N 2.95Å; V153-I155 PolarHBondContact O-N 3.25Å; I155-G158 PolarHBondContact O-N 3.31Å; I155-L159 HydrophobicContact CG2-CD1 4.2Å; I155-L159 WeakPolarHBondContact O-CG 3.42Å; I155-L159 PolarHBondContact O-N 3.23Å; I155-L405 HydrophobicContact CD1-CD1 4.41Å; I155-L405 HydrophobicContact CG1-CD1 3.89Å; I155-L405 HydrophobicContact CG1-CD2 4.32Å
156	L	96.2	Very high	95.3	Very high	112 Å²	112	34.1 Å²	34.1	59%	0.586	18%	0.178	S	C	*	.	H	α-helix	trans	-63.1	-44.9	-178.9	-71.8	171.7	0	0	0	111.8	C152 V153 L159 L160	C152-L156 WeakPolarHBondContact O-CB 3.43Å; C152-L156 VanDerWaalsContact O-CG 3.26Å; C152-L156 WeakPolarHBondContact O-CG 3.4Å; C152-L156 PolarHBondContact O-N 3.04Å; V153-L156 PolarHBondContact O-N 3.13Å; L156-L159 PolarHBondContact O-N 3.09Å; L156-L160 VanDerWaalsContact O-CB 3.29Å; L156-L160 WeakPolarHBondContact O-CB 3.29Å; L156-L160 PolarHBondContact O-N 3.23Å
157	M	95.5	Very high	95.2	Very high	16 Å²	16	35.8 Å²	35.8	8%	0.079	18%	0.184	C	C	.	.	H	α-helix	trans	-65.9	-38.7	176.3	-73.2	-63.8	-63.6	0	0	111.8	V153 L160 T161 T363 L366 T367 F519	V153-M157 HydrophobicContact CG1-CG 4.06Å; V153-M157 VanDerWaalsContact O-CB 3.22Å; V153-M157 WeakPolarHBondContact O-CB 3.31Å; V153-M157 VanDerWaalsContact O-CG 3.26Å; V153-M157 WeakPolarHBondContact O-CG 3.47Å; V153-M157 PolarHBondContact O-N 3.29Å; M157-L160 PolarHBondContact O-N 3.38Å; M157-L160 HydrophobicContact SD-CD2 4.45Å; M157-T161 HydrophobicContact CE-CG2 4.42Å; M157-T161 VanDerWaalsContact O-CB 3.31Å; M157-T161 WeakPolarHBondContact O-CB 3.41Å; M157-T161 WeakPolarHBondContact O-CG2 3.23Å; M157-T161 PolarHBondContact O-N 3.29Å; M157-T161 PolarHBondContact O-OG1 3.33Å; M157-T363 HydrophobicContact CG-CG2 4.39Å; M157-T363 HydrophobicContact SD-CG2 4.37Å; M157-L366 HydrophobicContact CB-CB 4.21Å; M157-L366 HydrophobicContact CB-CD1 4.02Å; M157-L366 HydrophobicContact CG-CB 4.4Å; M157-L366 HydrophobicContact CG-CD1 4.04Å; M157-T367 VanDerWaalsContact CE-OG1 3.26Å; M157-T367 WeakPolarHBondContact CE-OG1 3.42Å; M157-F519 HydrophobicContact CE-CZ 4.17Å
158	G	95.8	Very high	95.1	Very high	3 Å²	3	34.5 Å²	34.5	3%	0.031	18%	0.179	C	C	.	.	H	α-helix	trans	-60.5	-45	174.5	0	0	0	0	0	112.4	I154 I155 T161 L162	I154-G158 PolarHBondContact O-N 3.45Å; I155-G158 PolarHBondContact O-N 3.31Å; G158-T161 PolarHBondContact O-OG1 3.49Å; G158-T161 VanDerWaalsContact O-OG1 3.13Å; G158-L162 VanDerWaalsContact O-CB 3.23Å; G158-L162 WeakPolarHBondContact O-CB 3.07Å; G158-L162 PolarHBondContact O-N 3.1Å
159	L	96.5	Very high	94.9	Very high	97 Å²	97	32.8 Å²	32.8	51%	0.508	17%	0.168	S	C	.	.	H	α-helix	trans	-66.8	-43.4	176.5	-69.4	174.3	0	0	0	112.5	I155 L156 Y163	I155-L159 HydrophobicContact CG2-CD1 4.2Å; I155-L159 WeakPolarHBondContact O-CG 3.42Å; I155-L159 PolarHBondContact O-N 3.23Å; L156-L159 PolarHBondContact O-N 3.09Å; L159-Y163 WeakPolarHBondContact O-CB 3.43Å; L159-Y163 PolarHBondContact O-N 3.24Å
160	L	95.7	Very high	94.7	Very high	33 Å²	33	34.9 Å²	34.9	17%	0.173	18%	0.175	C	C	.	.	H	α-helix	trans	-64.8	-46.8	-179.9	-177.8	60.9	0	0	0	111.5	L156 M157 Y163 C164 F519 I547 L550	L156-L160 VanDerWaalsContact O-CB 3.29Å; L156-L160 WeakPolarHBondContact O-CB 3.29Å; L156-L160 PolarHBondContact O-N 3.23Å; M157-L160 PolarHBondContact O-N 3.38Å; M157-L160 HydrophobicContact SD-CD2 4.45Å; L160-Y163 WeakPolarHBondContact O-CB 3.26Å; L160-Y163 PolarHBondContact O-N 3.11Å; L160-C164 PolarHBondContact O-N 3.03Å; L160-C164 PolarHBondContact O-SG 3.33Å; L160-F519 HydrophobicContact CD2-CD1 4.4Å; L160-F519 HydrophobicContact CD2-CE1 3.57Å; L160-F519 HydrophobicContact CD2-CZ 4.39Å; L160-F519 HydrophobicContact CG-CE1 3.98Å; L160-I547 HydrophobicContact CD1-CD1 4.17Å; L160-I547 HydrophobicContact CD1-CG1 4.03Å; L160-I547 HydrophobicContact CD1-CG2 4.31Å; L160-L550 HydrophobicContact CD2-CD1 4.37Å
161	T	94.9	Very high	94.3	Very high	0 Å²	0	35.2 Å²	35.2	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-67.5	-38.3	179.3	54.3	0	0	0	0	112	M157 G158 C164 C165 F370 H373 V518	M157-T161 HydrophobicContact CE-CG2 4.42Å; M157-T161 VanDerWaalsContact O-CB 3.31Å; M157-T161 WeakPolarHBondContact O-CB 3.41Å; M157-T161 WeakPolarHBondContact O-CG2 3.23Å; M157-T161 PolarHBondContact O-N 3.29Å; M157-T161 PolarHBondContact O-OG1 3.33Å; G158-T161 PolarHBondContact O-OG1 3.49Å; G158-T161 VanDerWaalsContact O-OG1 3.13Å; T161-C164 PolarHBondContact O-N 3.32Å; T161-C165 VanDerWaalsContact O-CB 3.31Å; T161-C165 WeakPolarHBondContact O-CB 3.46Å; T161-C165 PolarHBondContact O-N 3.24Å; T161-F370 HydrophobicContact CG2-CB 3.94Å; T161-F370 WeakPolarHBondContact OG1-CB 3.44Å; T161-H373 PolarHBondContact O-NE2 2.69Å; T161-V518 HydrophobicContact CG2-CG1 3.99Å
162	L	96	Very high	93.6	Very high	25 Å²	25	34.5 Å²	34.5	13%	0.131	17%	0.172	C	C	.	.	H	α-helix	trans	-58.3	-48	170.9	170.5	58.3	0	0	0	111.2	G158 C164 C165 Y166 L393 Y397	G158-L162 VanDerWaalsContact O-CB 3.23Å; G158-L162 WeakPolarHBondContact O-CB 3.07Å; G158-L162 PolarHBondContact O-N 3.1Å; L162-C164 PolarHBondContact O-N 3.19Å; L162-C165 PolarHBondContact O-N 3.3Å; L162-Y166 WeakPolarHBondContact O-CB 3.32Å; L162-Y166 PolarHBondContact O-N 2.94Å; L162-L393 HydrophobicContact CD1-CD2 4.38Å; L162-L393 HydrophobicContact CD1-CG 4.08Å; L162-Y397 HydrophobicContact CB-CD1 3.74Å; L162-Y397 HydrophobicContact CB-CE1 4.25Å; L162-Y397 HydrophobicContact CB-CG 3.89Å; L162-Y397 HydrophobicContact CD1-CD1 4.48Å; L162-Y397 HydrophobicContact CD1-CD2 3.76Å; L162-Y397 HydrophobicContact CD1-CE2 4.41Å; L162-Y397 HydrophobicContact CD1-CG 3.79Å; L162-Y397 HydrophobicContact CG-CG 4.32Å
163	Y	95.9	Very high	92.7	Very high	56 Å²	56	36 Å²	36	22%	0.22	18%	0.179	C	C	.	.	H	α-helix	trans	-59.1	-46.5	177.3	174.4	-99.6	0	0	0	111.7	L159 L160 C165 Y166 R167 F543 H544 I547	L159-Y163 WeakPolarHBondContact O-CB 3.43Å; L159-Y163 PolarHBondContact O-N 3.24Å; L160-Y163 WeakPolarHBondContact O-CB 3.26Å; L160-Y163 PolarHBondContact O-N 3.11Å; Y163-C165 VanDerWaalsContact C-N 3.33Å; Y163-C165 PolarHBondContact O-N 2.69Å; Y163-Y166 WeakPolarHBondContact O-CB 3.35Å; Y163-Y166 PolarHBondContact O-N 3.46Å; Y163-R167 HydrophobicContact CE1-CG 4.11Å; Y163-R167 VanDerWaalsContact CZ-NE 3.3Å; Y163-R167 WeakPolarHBondContact O-CG 3.38Å; Y163-R167 PolarHBondContact O-N 3.37Å; Y163-R167 VanDerWaalsContact OH-CZ 3.28Å; Y163-R167 PolarHBondContact OH-NE 3.14Å; Y163-R167 PolarHBondContact OH-NH2 2.98Å; Y163-F543 HydrophobicContact CD1-CE1 4.48Å; Y163-F543 AromaticContact CE1-CE1 3.76Å; Y163-F543 HydrophobicContact CE1-CE1 3.76Å; Y163-F543 HydrophobicContact CE2-CE1 4.47Å; Y163-F543 AromaticContact CZ-CE1 3.73Å; Y163-H544 AromaticContact CE1-NE2 3.96Å; Y163-H544 AromaticContact CZ-NE2 3.75Å; Y163-H544 PolarHBondContact OH-CE1 3.32Å; Y163-H544 PolarHBondContact OH-NE2 2.8Å; Y163-I547 HydrophobicContact CD1-CD1 3.93Å; Y163-I547 HydrophobicContact CE1-CD1 3.65Å
164	C	94.8	Very high	91.9	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-62.8	-40.3	176.6	-68.4	0	0	0	0	112.1	L160 T161 L162 R167 V168 V518	L160-C164 PolarHBondContact O-N 3.03Å; L160-C164 PolarHBondContact O-SG 3.33Å; T161-C164 PolarHBondContact O-N 3.32Å; L162-C164 PolarHBondContact O-N 3.19Å; C164-R167 WeakPolarHBondContact O-CB 3.31Å; C164-R167 PolarHBondContact O-N 3.32Å; C164-R167 VanDerWaalsContact O-N 3.15Å; C164-V168 WeakPolarHBondContact O-CG2 3.45Å; C164-V168 PolarHBondContact O-N 2.98Å; C164-V518 HydrophobicContact CB-CG1 4.07Å; C164-V518 WeakPolarHBondContact CB-O 3.41Å; C164-V518 PolarHBondContact SG-O 2.75Å
165	C	93.6	Very high	91.1	Very high	0 Å²	0	37.9 Å²	37.9	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-65.9	-40.4	177.5	-161.1	0	0	0	0	111.4	T161 L162 Y163 R167 V168 V169 H373 L393 Y397	T161-C165 VanDerWaalsContact O-CB 3.31Å; T161-C165 WeakPolarHBondContact O-CB 3.46Å; T161-C165 PolarHBondContact O-N 3.24Å; L162-C165 PolarHBondContact O-N 3.3Å; Y163-C165 VanDerWaalsContact C-N 3.33Å; Y163-C165 PolarHBondContact O-N 2.69Å; C165-R167 VanDerWaalsContact C-N 3.27Å; C165-R167 PolarHBondContact O-N 2.95Å; C165-V168 WeakPolarHBondContact O-CB 3.46Å; C165-V168 PolarHBondContact O-N 3.1Å; C165-V168 VanDerWaalsContact O-N 3.16Å; C165-V169 WeakPolarHBondContact O-CG2 3.41Å; C165-V169 PolarHBondContact O-N 3.27Å; C165-H373 PolarHBondContact N-NE2 3.1Å; C165-L393 HydrophobicContact CB-CD2 4.38Å; C165-Y397 HydrophobicContact CB-CE2 3.91Å; C165-Y397 VanDerWaalsContact CB-OH 3.27Å; C165-Y397 WeakPolarHBondContact CB-OH 2.99Å; C165-Y397 PolarHBondContact SG-OH 3.29Å; C165-Y397 VanDerWaalsContact SG-OH 3.41Å
166	Y	94.2	Very high	89.3	Confident	65 Å²	65	39.8 Å²	39.8	26%	0.255	21%	0.208	S	C	.	.	H	α-helix	trans	-56.6	-41.7	171.2	166.2	-101.1	0	0	0	111.8	L162 Y163 V169 K170 V390	L162-Y166 WeakPolarHBondContact O-CB 3.32Å; L162-Y166 PolarHBondContact O-N 2.94Å; Y163-Y166 WeakPolarHBondContact O-CB 3.35Å; Y163-Y166 PolarHBondContact O-N 3.46Å; Y166-V169 PolarHBondContact O-N 3.04Å; Y166-K170 HydrophobicContact CE1-CD 4.09Å; Y166-K170 HydrophobicContact CE2-CD 4.46Å; Y166-K170 WeakPolarHBondContact O-CB 3.3Å; Y166-K170 PolarHBondContact O-N 3.25Å; Y166-K170 WeakPolarHBondContact OH-CD 3.5Å; Y166-K170 PolarHBondContact OH-NZ 3.22Å; Y166-K170 VanDerWaalsContact OH-NZ 3.08Å; Y166-V390 HydrophobicContact CD2-CG1 3.75Å; Y166-V390 HydrophobicContact CD2-CG2 4.12Å; Y166-V390 HydrophobicContact CE2-CG1 3.73Å; Y166-V390 HydrophobicContact CE2-CG2 3.89Å
167	R	92.9	Very high	87.6	Confident	34 Å²	34	38.8 Å²	38.8	13%	0.128	21%	0.21	C	C	.	.	H	α-helix	trans	-64.1	-41.1	175.7	-66.6	-61	-176.9	-179.8	2.5	112.4	Y163 C164 C165 V169 K170 S171 P522 Y526	Y163-R167 HydrophobicContact CE1-CG 4.11Å; Y163-R167 VanDerWaalsContact CZ-NE 3.3Å; Y163-R167 WeakPolarHBondContact O-CG 3.38Å; Y163-R167 PolarHBondContact O-N 3.37Å; Y163-R167 VanDerWaalsContact OH-CZ 3.28Å; Y163-R167 PolarHBondContact OH-NE 3.14Å; Y163-R167 PolarHBondContact OH-NH2 2.98Å; C164-R167 WeakPolarHBondContact O-CB 3.31Å; C164-R167 PolarHBondContact O-N 3.32Å; C164-R167 VanDerWaalsContact O-N 3.15Å; C165-R167 VanDerWaalsContact C-N 3.27Å; C165-R167 PolarHBondContact O-N 2.95Å; R167-V169 VanDerWaalsContact C-N 3.34Å; R167-V169 PolarHBondContact O-N 2.98Å; R167-K170 PolarHBondContact O-N 2.87Å; R167-S171 PolarHBondContact O-N 3.32Å; R167-P522 HydrophobicContact CB-CB 3.88Å; R167-Y526 VanDerWaalsContact NH1-CD2 3.34Å
168	V	91.2	Very high	86.3	Confident	0 Å²	0	42.5 Å²	42.5	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-59.9	-42.7	173.2	170.8	0	0	0	0	111.9	C164 C165 S171 Y185 H373 I376 I377 P522	C164-V168 WeakPolarHBondContact O-CG2 3.45Å; C164-V168 PolarHBondContact O-N 2.98Å; C165-V168 WeakPolarHBondContact O-CB 3.46Å; C165-V168 PolarHBondContact O-N 3.1Å; C165-V168 VanDerWaalsContact O-N 3.16Å; V168-S171 PolarHBondContact O-OG 3.39Å; V168-Y185 HydrophobicContact CB-CD2 4.45Å; V168-Y185 HydrophobicContact CB-CE2 4.15Å; V168-Y185 HydrophobicContact CG1-CD1 4.29Å; V168-Y185 HydrophobicContact CG1-CD2 3.55Å; V168-Y185 HydrophobicContact CG1-CE1 4.49Å; V168-Y185 HydrophobicContact CG1-CE2 3.74Å; V168-Y185 HydrophobicContact CG1-CG 3.86Å; V168-Y185 HydrophobicContact CG2-CD2 4.49Å; V168-Y185 HydrophobicContact CG2-CE1 4.14Å; V168-Y185 HydrophobicContact CG2-CE2 3.86Å; V168-H373 HydrophobicContact CG2-CB 4.37Å; V168-I376 HydrophobicContact CG1-CG2 3.85Å; V168-I377 HydrophobicContact CG1-CD1 4.3Å; V168-I377 HydrophobicContact CG1-CG1 4.48Å; V168-P522 HydrophobicContact CG2-CB 4.04Å; V168-P522 HydrophobicContact CG2-CG 3.59Å
169	V	89.6	Confident	84.8	Confident	14 Å²	14	48.1 Å²	48.1	9%	0.085	26%	0.259	C	S	.	.	H	α-helix	trans	-67.9	-40.6	178.5	174.8	0	0	0	0	111	C165 Y166 R167 I376 L380 L393	C165-V169 WeakPolarHBondContact O-CG2 3.41Å; C165-V169 PolarHBondContact O-N 3.27Å; Y166-V169 PolarHBondContact O-N 3.04Å; R167-V169 VanDerWaalsContact C-N 3.34Å; R167-V169 PolarHBondContact O-N 2.98Å; V169-I376 HydrophobicContact CG2-CG1 3.85Å; V169-I376 HydrophobicContact CG2-CG2 4.03Å; V169-L380 HydrophobicContact CB-CD1 4.37Å; V169-L380 HydrophobicContact CG1-CD1 3.85Å; V169-L380 HydrophobicContact CG2-CD1 3.52Å; V169-L393 HydrophobicContact CG2-CD2 4.16Å
170	K	89	Confident	83.3	Confident	71 Å²	71	44.5 Å²	44.5	31%	0.309	24%	0.242	S	C	.	.	H	α-helix	trans	-75	-21.5	-178.6	-164.6	169.9	-168.9	173.1	0	113.7	Y166 R167 R172 T173 M174	Y166-K170 HydrophobicContact CE1-CD 4.09Å; Y166-K170 HydrophobicContact CE2-CD 4.46Å; Y166-K170 WeakPolarHBondContact O-CB 3.3Å; Y166-K170 PolarHBondContact O-N 3.25Å; Y166-K170 WeakPolarHBondContact OH-CD 3.5Å; Y166-K170 PolarHBondContact OH-NZ 3.22Å; Y166-K170 VanDerWaalsContact OH-NZ 3.08Å; R167-K170 PolarHBondContact O-N 2.87Å; K170-R172 PolarHBondContact O-N 2.96Å; K170-T173 PolarHBondContact O-N 2.73Å; K170-T173 VanDerWaalsContact O-N 3.08Å; K170-T173 PolarHBondContact O-OG1 2.9Å; K170-M174 HydrophobicContact CD-CE 4.06Å; K170-M174 HydrophobicContact CG-CE 4.21Å; K170-M174 WeakPolarHBondContact O-CG 2.97Å; K170-M174 PolarHBondContact O-N 3.33Å
171	S	86.3	Confident	81.7	Confident	6 Å²	6	46.5 Å²	46.5	4%	0.042	26%	0.255	C	S	.	.	H	α-helix	trans	-60.7	-30.5	-178.5	63.5	0	0	0	0	112.8	R167 V168 M174	R167-S171 PolarHBondContact O-N 3.32Å; V168-S171 PolarHBondContact O-OG 3.39Å; S171-M174 PolarHBondContact O-N 3.07Å
172	R	81.4	Confident	80.2	Confident	31 Å²	31	50.1 Å²	50.1	12%	0.117	28%	0.277	C	S	.	.	H	α-helix	trans	-65	-42.9	174.1	-70.2	-167.1	-64.2	164.8	0.8	112.6	K170 M174 I175 V188 I377	K170-R172 PolarHBondContact O-N 2.96Å; R172-M174 PolarHBondContact O-N 3.41Å; R172-I175 PolarHBondContact O-N 2.98Å; R172-V188 HydrophobicContact CG-CG2 4.06Å; R172-I377 HydrophobicContact CG-CD1 3.97Å
173	T	78.4	Confident	79.1	Confident	99 Å²	99	51.1 Å²	51.1	61%	0.607	28%	0.28	S	S	*	.	H	α-helix	trans	-73.3	-17	-178.2	58.9	0	0	0	0	113.4	K170 I175	K170-T173 PolarHBondContact O-N 2.73Å; K170-T173 VanDerWaalsContact O-N 3.08Å; K170-T173 PolarHBondContact O-OG1 2.9Å; T173-I175 VanDerWaalsContact C-N 3.34Å
174	M	78.9	Confident	78.2	Confident	45 Å²	45	51.1 Å²	51.1	22%	0.222	28%	0.282	C	S	.	.	H	α-helix	trans	-76.2	-23.1	176.1	-65.4	-59.2	-157.6	0	0	112.5	K170 S171 R172 S176 Y526	K170-M174 HydrophobicContact CD-CE 4.06Å; K170-M174 HydrophobicContact CG-CE 4.21Å; K170-M174 WeakPolarHBondContact O-CG 2.97Å; K170-M174 PolarHBondContact O-N 3.33Å; S171-M174 PolarHBondContact O-N 3.07Å; R172-M174 PolarHBondContact O-N 3.41Å; M174-S176 PolarHBondContact O-N 3.48Å; M174-Y526 HydrophobicContact CE-CD2 4.28Å; M174-Y526 HydrophobicContact CE-CE2 3.95Å
175	I	78.9	Confident	77.6	Confident	11 Å²	11	51.1 Å²	51.1	6%	0.056	28%	0.282	C	S	.	.			trans	-84.7	92.8	177.7	-57.9	162.5	0	0	0	107.6	R172 T173 S177 T180 W183 V188 Y192	R172-I175 PolarHBondContact O-N 2.98Å; T173-I175 VanDerWaalsContact C-N 3.34Å; I175-S177 VanDerWaalsContact C-N 3.35Å; I175-T180 HydrophobicContact CB-CG2 4.01Å; I175-T180 HydrophobicContact CD1-CG2 4.37Å; I175-T180 HydrophobicContact CG2-CG2 3.89Å; I175-W183 HydrophobicContact CD1-CE3 4.4Å; I175-W183 HydrophobicContact CD1-CZ3 4.03Å; I175-V188 HydrophobicContact CD1-CG1 4.19Å; I175-Y192 HydrophobicContact CD1-CE2 3.85Å; I175-Y192 HydrophobicContact CG1-CE2 3.96Å
176	S	59.8	Low	76.9	Confident	117 Å²	117	52.6 Å²	52.6	82%	0.818	29%	0.291	S	S	*	.			trans	-84.8	-6	-177.9	-62.1	0	0	0	0	113.9	M174	M174-S176 PolarHBondContact O-N 3.48Å
177	S	61	Low	76.3	Confident	91 Å²	91	52.5 Å²	52.5	64%	0.636	30%	0.295	S	S	*	.	S	Bend	trans	-96.2	-13.5	-168.2	56.2	0	0	0	0	115.6	I175	I175-S177 VanDerWaalsContact C-N 3.35Å
178	L	68.2	Low	75.8	Confident	94 Å²	94	50.9 Å²	50.9	49%	0.492	29%	0.289	S	S	.	.	S	Bend	trans	-139.2	154.3	-178	-82.8	92	0	0	0	111.7	T180 W183	L178-T180 PolarHBondContact O-N 2.65Å; L178-W183 HydrophobicContact CB-CH2 4.39Å; L178-W183 HydrophobicContact CB-CZ2 4.31Å; L178-W183 HydrophobicContact CD2-CH2 4.23Å; L178-W183 HydrophobicContact CD2-CZ2 3.93Å
179	D	63.3	Low	75.5	Confident	121 Å²	121	50.9 Å²	50.9	65%	0.647	29%	0.289	S	S	*	.			trans	-68.6	100.2	169.4	-167.8	-6.3	0	0	0	109.7	T181	D179-T181 VanDerWaalsContact C-N 3.34Å; D179-T181 WeakPolarHBondContact OD1-CB 3.18Å; D179-T181 WeakPolarHBondContact OD1-CG2 3.09Å; D179-T181 PolarHBondContact OD1-N 2.9Å; D179-T181 PolarHBondContact OD1-OG1 3.35Å
180	T	64.9	Low	75.4	Confident	22 Å²	22	56.6 Å²	56.6	14%	0.135	31%	0.309	C	S	.	.			trans	-93.5	10.6	-176.6	54.1	0	0	0	0	112.9	I175 L178 T182 W183	I175-T180 HydrophobicContact CB-CG2 4.01Å; I175-T180 HydrophobicContact CD1-CG2 4.37Å; I175-T180 HydrophobicContact CG2-CG2 3.89Å; L178-T180 PolarHBondContact O-N 2.65Å; T180-T182 PolarHBondContact O-N 2.96Å; T180-W183 HydrophobicContact CG2-CD2 4.03Å; T180-W183 HydrophobicContact CG2-CE3 3.8Å; T180-W183 HydrophobicContact CG2-CH2 4.43Å; T180-W183 HydrophobicContact CG2-CZ3 4.01Å; T180-W183 PolarHBondContact O-N 2.98Å; T180-W183 VanDerWaalsContact O-N 3.14Å
181	T	62.4	Low	75.2	Confident	74 Å²	74	57.3 Å²	57.3	45%	0.454	31%	0.313	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.9	-26.8	-173.2	51.7	0	0	0	0	113.8	D179 K381	D179-T181 VanDerWaalsContact C-N 3.34Å; D179-T181 WeakPolarHBondContact OD1-CB 3.18Å; D179-T181 WeakPolarHBondContact OD1-CG2 3.09Å; D179-T181 PolarHBondContact OD1-N 2.9Å; D179-T181 PolarHBondContact OD1-OG1 3.35Å; T181-K381 WeakPolarHBondContact O-CE 3.19Å; T181-K381 PolarHBondContact O-NZ 2.61Å
182	T	64.6	Low	75.3	Confident	77 Å²	77	58.6 Å²	58.6	47%	0.472	32%	0.317	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.6	-6.7	178.5	55	0	0	0	0	114.2	E112 T180	E112-T182 WeakPolarHBondContact OE2-CG2 3.37Å; T180-T182 PolarHBondContact O-N 2.96Å
183	W	72.8	Confident	75.6	Confident	46 Å²	46	59.5 Å²	59.5	17%	0.174	32%	0.322	C	S	.	.			trans	-80	131.6	-170.4	-68.6	15.8	0	0	0	111.7	I175 L178 T180 D187 H191 I377	I175-W183 HydrophobicContact CD1-CE3 4.4Å; I175-W183 HydrophobicContact CD1-CZ3 4.03Å; L178-W183 HydrophobicContact CB-CH2 4.39Å; L178-W183 HydrophobicContact CB-CZ2 4.31Å; L178-W183 HydrophobicContact CD2-CH2 4.23Å; L178-W183 HydrophobicContact CD2-CZ2 3.93Å; T180-W183 HydrophobicContact CG2-CD2 4.03Å; T180-W183 HydrophobicContact CG2-CE3 3.8Å; T180-W183 HydrophobicContact CG2-CH2 4.43Å; T180-W183 HydrophobicContact CG2-CZ3 4.01Å; T180-W183 PolarHBondContact O-N 2.98Å; T180-W183 VanDerWaalsContact O-N 3.14Å; W183-D187 HydrophobicContact CB-CB 4.07Å; W183-D187 HydrophobicContact CG-CB 4.24Å; W183-H191 HydrophobicContact CH2-CB 4.32Å; W183-H191 AromaticContact CH2-ND1 3.92Å; W183-H191 HydrophobicContact CZ3-CB 3.8Å; W183-H191 AromaticContact CZ3-CG 3.91Å; W183-I377 WeakPolarHBondContact O-CG2 3.23Å
184	E	77.1	Confident	76.1	Confident	56 Å²	56	56.4 Å²	56.4	26%	0.262	31%	0.309	S	S	.	.			trans	-90.3	169.2	169	-67.9	-62.3	168.8	0	0	111	P186 D187 V188 T378	E184-P186 VanDerWaalsContact C-CD 3.48Å; E184-D187 PolarHBondContact N-OD2 3.47Å; E184-D187 WeakPolarHBondContact O-CB 3.15Å; E184-D187 PolarHBondContact O-N 2.94Å; E184-V188 PolarHBondContact O-N 3.35Å; E184-V188 VanDerWaalsContact O-N 3.15Å; E184-T378 WeakPolarHBondContact OE1-CB 3.45Å; E184-T378 PolarHBondContact OE1-OG1 3.49Å; E184-T378 PolarHBondContact OE2-OG1 3.29Å
185	Y	80.7	Confident	76.5	Confident	0 Å²	0	58.1 Å²	58.1	0%	0	33%	0.326	C	S	.	.	H	α-helix	trans	-58	-38.3	-176.1	-169.4	-126.1	0	0	0	114.5	V168 D187 V188 C189 I377 F517 Y521 I525	V168-Y185 HydrophobicContact CB-CD2 4.45Å; V168-Y185 HydrophobicContact CB-CE2 4.15Å; V168-Y185 HydrophobicContact CG1-CD1 4.29Å; V168-Y185 HydrophobicContact CG1-CD2 3.55Å; V168-Y185 HydrophobicContact CG1-CE1 4.49Å; V168-Y185 HydrophobicContact CG1-CE2 3.74Å; V168-Y185 HydrophobicContact CG1-CG 3.86Å; V168-Y185 HydrophobicContact CG2-CD2 4.49Å; V168-Y185 HydrophobicContact CG2-CE1 4.14Å; V168-Y185 HydrophobicContact CG2-CE2 3.86Å; Y185-D187 VanDerWaalsContact C-N 3.26Å; Y185-D187 PolarHBondContact O-N 3.36Å; Y185-V188 HydrophobicContact CD2-CB 4.33Å; Y185-V188 WeakPolarHBondContact O-CB 3.38Å; Y185-V188 PolarHBondContact O-N 2.78Å; Y185-C189 PolarHBondContact O-N 3.49Å; Y185-C189 PolarHBondContact O-SG 3.14Å; Y185-I377 HydrophobicContact CD2-CD1 4.15Å; Y185-I377 HydrophobicContact CG-CD1 4.45Å; Y185-F517 AromaticContact CD1-CD1 3.46Å; Y185-F517 HydrophobicContact CD1-CD1 3.46Å; Y185-F517 VanDerWaalsContact CD1-CD1 3.46Å; Y185-F517 AromaticContact CD1-CE1 3.48Å; Y185-F517 HydrophobicContact CD1-CE1 3.48Å; Y185-F517 VanDerWaalsContact CD1-CE1 3.48Å; Y185-F517 AromaticContact CE1-CD1 3.41Å; Y185-F517 HydrophobicContact CE1-CD1 3.41Å; Y185-F517 VanDerWaalsContact CE1-CD1 3.41Å; Y185-F517 AromaticContact CE1-CE1 3.75Å; Y185-F517 HydrophobicContact CE1-CE1 3.75Å; Y185-Y521 WeakPolarHBondContact OH-CB 3.26Å; Y185-I525 HydrophobicContact CE2-CD1 4.07Å
186	P	79.9	Confident	76.9	Confident	30 Å²	30	65.1 Å²	65.1	20%	0.195	36%	0.356	C	S	.	.	H	α-helix	trans	-60.3	-33.1	172.2	-25.1	36.5	0	0	0	113.7	E184 C189 R190	E184-P186 VanDerWaalsContact C-CD 3.48Å; P186-C189 WeakPolarHBondContact O-CB 3.45Å; P186-C189 PolarHBondContact O-N 2.78Å; P186-R190 PolarHBondContact O-N 3.04Å
187	D	80.4	Confident	78.1	Confident	63 Å²	63	59.6 Å²	59.6	34%	0.337	32%	0.317	S	S	.	.	H	α-helix	trans	-70.9	-36.4	177.8	-56.4	-45.1	0	0	0	111.2	W183 E184 Y185 C189 R190 H191	W183-D187 HydrophobicContact CB-CB 4.07Å; W183-D187 HydrophobicContact CG-CB 4.24Å; E184-D187 PolarHBondContact N-OD2 3.47Å; E184-D187 WeakPolarHBondContact O-CB 3.15Å; E184-D187 PolarHBondContact O-N 2.94Å; Y185-D187 VanDerWaalsContact C-N 3.26Å; Y185-D187 PolarHBondContact O-N 3.36Å; D187-C189 VanDerWaalsContact C-N 3.3Å; D187-C189 PolarHBondContact O-N 3.36Å; D187-R190 WeakPolarHBondContact O-CB 3.28Å; D187-R190 PolarHBondContact O-N 2.93Å; D187-H191 PolarHBondContact O-N 3.32Å
188	V	84.1	Confident	79.3	Confident	0 Å²	0	56.4 Å²	56.4	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-60.3	-43.2	170.1	-177.8	0	0	0	0	110.2	R172 I175 E184 Y185 R190 H191 Y192 I525	R172-V188 HydrophobicContact CG-CG2 4.06Å; I175-V188 HydrophobicContact CD1-CG1 4.19Å; E184-V188 PolarHBondContact O-N 3.35Å; E184-V188 VanDerWaalsContact O-N 3.15Å; Y185-V188 HydrophobicContact CD2-CB 4.33Å; Y185-V188 WeakPolarHBondContact O-CB 3.38Å; Y185-V188 PolarHBondContact O-N 2.78Å; V188-R190 VanDerWaalsContact C-N 3.32Å; V188-R190 PolarHBondContact O-N 3.42Å; V188-H191 PolarHBondContact O-N 2.86Å; V188-Y192 HydrophobicContact CG1-CD2 4.08Å; V188-Y192 HydrophobicContact CG1-CE2 4.06Å; V188-Y192 WeakPolarHBondContact O-CD2 3.41Å; V188-Y192 PolarHBondContact O-N 3.47Å; V188-I525 HydrophobicContact CG1-CD1 4.27Å
189	C	84.4	Confident	80.2	Confident	0 Å²	0	58.9 Å²	58.9	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-63.6	-37.4	176.4	-62.6	0	0	0	0	112	Y185 P186 D187 H191 Y192 F193	Y185-C189 PolarHBondContact O-N 3.49Å; Y185-C189 PolarHBondContact O-SG 3.14Å; P186-C189 WeakPolarHBondContact O-CB 3.45Å; P186-C189 PolarHBondContact O-N 2.78Å; D187-C189 VanDerWaalsContact C-N 3.3Å; D187-C189 PolarHBondContact O-N 3.36Å; C189-H191 VanDerWaalsContact C-N 3.32Å; C189-H191 PolarHBondContact O-N 3.45Å; C189-Y192 PolarHBondContact O-N 3.28Å; C189-F193 HydrophobicContact CB-CD2 4.49Å; C189-F193 WeakPolarHBondContact O-CB 3.25Å; C189-F193 WeakPolarHBondContact O-CD2 3.39Å; C189-F193 PolarHBondContact O-N 3.43Å
190	R	86.3	Confident	81.5	Confident	135 Å²	135	54.1 Å²	54.1	51%	0.509	27%	0.271	S	S	.	.	H	α-helix	trans	-61.5	-39.4	174	-179.1	-177.3	169.9	127.4	-8	111.9	P186 D187 V188 G194 Q198	P186-R190 PolarHBondContact O-N 3.04Å; D187-R190 WeakPolarHBondContact O-CB 3.28Å; D187-R190 PolarHBondContact O-N 2.93Å; V188-R190 VanDerWaalsContact C-N 3.32Å; V188-R190 PolarHBondContact O-N 3.42Å; R190-G194 WeakPolarHBondContact O-CA 3.17Å; R190-G194 PolarHBondContact O-N 3.47Å; R190-Q198 HydrophobicContact CB-CB 4.07Å; R190-Q198 HydrophobicContact CB-CG 4.4Å; R190-Q198 HydrophobicContact CG-CB 4.2Å; R190-Q198 VanDerWaalsContact NH1-CD 3.34Å
191	H	86.6	Confident	82.6	Confident	86 Å²	86	53 Å²	53	40%	0.398	27%	0.265	S	S	.	.	H	α-helix	trans	-64.9	-44.9	180	-174.7	71.1	0	0	0	112.6	W183 D187 V188 C189	W183-H191 HydrophobicContact CH2-CB 4.32Å; W183-H191 AromaticContact CH2-ND1 3.92Å; W183-H191 HydrophobicContact CZ3-CB 3.8Å; W183-H191 AromaticContact CZ3-CG 3.91Å; D187-H191 PolarHBondContact O-N 3.32Å; V188-H191 PolarHBondContact O-N 2.86Å; C189-H191 VanDerWaalsContact C-N 3.32Å; C189-H191 PolarHBondContact O-N 3.45Å
192	Y	87.1	Confident	83.7	Confident	33 Å²	33	50.3 Å²	50.3	13%	0.129	25%	0.248	C	C	.	.	H	α-helix	trans	-80.8	-35.8	-176.6	-78	-79.2	0	0	0	114.4	I175 V188 C189 I525 I528	I175-Y192 HydrophobicContact CD1-CE2 3.85Å; I175-Y192 HydrophobicContact CG1-CE2 3.96Å; V188-Y192 HydrophobicContact CG1-CD2 4.08Å; V188-Y192 HydrophobicContact CG1-CE2 4.06Å; V188-Y192 WeakPolarHBondContact O-CD2 3.41Å; V188-Y192 PolarHBondContact O-N 3.47Å; C189-Y192 PolarHBondContact O-N 3.28Å; Y192-I525 HydrophobicContact CD2-CB 4.46Å; Y192-I525 HydrophobicContact CD2-CG1 4.05Å; Y192-I525 HydrophobicContact CD2-CG2 3.77Å; Y192-I525 HydrophobicContact CE1-CG2 4.45Å; Y192-I525 HydrophobicContact CE2-CG2 3.52Å; Y192-I525 HydrophobicContact CG-CG1 4.26Å; Y192-I525 HydrophobicContact CG-CG2 4.32Å; Y192-I528 HydrophobicContact CD1-CB 4.35Å; Y192-I528 HydrophobicContact CD1-CG2 3.84Å; Y192-I528 HydrophobicContact CE1-CG2 4.23Å
193	F	87.3	Confident	85	Confident	50 Å²	50	51.6 Å²	51.6	22%	0.219	25%	0.251	C	S	.	.	H	α-helix	trans	-115.1	3.2	-171.8	-57.6	-73	0	0	0	113.6	C189 Y521 L524 I525 I528	C189-F193 HydrophobicContact CB-CD2 4.49Å; C189-F193 WeakPolarHBondContact O-CB 3.25Å; C189-F193 WeakPolarHBondContact O-CD2 3.39Å; C189-F193 PolarHBondContact O-N 3.43Å; F193-Y521 HydrophobicContact CD2-CD1 4.36Å; F193-Y521 AromaticContact CE2-CD1 3.82Å; F193-Y521 HydrophobicContact CE2-CD1 3.82Å; F193-Y521 HydrophobicContact CE2-CE1 4.39Å; F193-Y521 HydrophobicContact CZ-CD1 4.36Å; F193-L524 HydrophobicContact CE1-CB 4.14Å; F193-L524 HydrophobicContact CE1-CD1 4.08Å; F193-L524 HydrophobicContact CZ-CB 3.65Å; F193-L524 HydrophobicContact CZ-CD1 4.09Å; F193-I525 HydrophobicContact CE2-CD1 4.25Å; F193-I525 HydrophobicContact CE2-CG1 3.71Å; F193-I525 HydrophobicContact CZ-CG1 4.11Å; F193-I528 HydrophobicContact CD1-CD1 4.39Å; F193-I528 HydrophobicContact CE1-CD1 3.64Å; F193-I528 HydrophobicContact CZ-CD1 4.06Å
194	G	89.3	Confident	85.8	Confident	33 Å²	33	51.8 Å²	51.8	34%	0.34	25%	0.253	S	S	.	.	H	α-helix	trans	64.8	-145.9	-178.2	0	0	0	0	0	113.5	R190 F196 G197 Q198	R190-G194 WeakPolarHBondContact O-CA 3.17Å; R190-G194 PolarHBondContact O-N 3.47Å; G194-F196 VanDerWaalsContact C-N 3.31Å; G194-F196 PolarHBondContact O-N 2.7Å; G194-G197 PolarHBondContact O-N 3.23Å; G194-Q198 PolarHBondContact O-N 3.43Å
195	S	86.7	Confident	86.3	Confident	81 Å²	81	49.2 Å²	49.2	57%	0.566	24%	0.241	S	C	*	.	H	α-helix	trans	-63.6	-34.9	-177.1	-174.3	0	0	0	0	113	Q198 W199	S195-Q198 PolarHBondContact O-N 2.92Å; S195-W199 PolarHBondContact O-N 3.39Å; S195-W199 VanDerWaalsContact O-N 3.14Å
196	F	88.8	Confident	86.6	Confident	159 Å²	159	50.2 Å²	50.2	70%	0.697	25%	0.246	S	C	*	.	H	α-helix	trans	-62.3	-47.4	177.9	176.5	-101.6	0	0	0	111.8	G194 Q198 W199 S200	G194-F196 VanDerWaalsContact C-N 3.31Å; G194-F196 PolarHBondContact O-N 2.7Å; F196-Q198 VanDerWaalsContact C-N 3.28Å; F196-Q198 PolarHBondContact O-N 3.13Å; F196-W199 PolarHBondContact O-N 3.33Å; F196-S200 WeakPolarHBondContact O-CB 3.1Å; F196-S200 PolarHBondContact O-N 3.01Å
197	G	84.8	Confident	87.1	Confident	0 Å²	0	51.3 Å²	51.3	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-65.3	-31.6	178.1	0	0	0	0	0	113.6	G194 S201	G194-G197 PolarHBondContact O-N 3.23Å; G197-S201 WeakPolarHBondContact O-CB 3.14Å; G197-S201 PolarHBondContact O-N 2.92Å; G197-S201 PolarHBondContact O-OG 3.39Å
198	Q	84.9	Confident	87.5	Confident	24 Å²	24	48.4 Å²	48.4	11%	0.112	24%	0.237	C	C	.	.	H	α-helix	trans	-66.5	-52.1	176.3	-170.8	177.3	15.8	0	0	112	R190 G194 S195 F196 S201 L202 H469	R190-Q198 HydrophobicContact CB-CB 4.07Å; R190-Q198 HydrophobicContact CB-CG 4.4Å; R190-Q198 HydrophobicContact CG-CB 4.2Å; R190-Q198 VanDerWaalsContact NH1-CD 3.34Å; G194-Q198 PolarHBondContact O-N 3.43Å; S195-Q198 PolarHBondContact O-N 2.92Å; F196-Q198 VanDerWaalsContact C-N 3.28Å; F196-Q198 PolarHBondContact O-N 3.13Å; Q198-S201 PolarHBondContact O-OG 2.76Å; Q198-L202 WeakPolarHBondContact O-CB 3.33Å; Q198-L202 PolarHBondContact O-N 3.41Å; Q198-H469 PolarHBondContact NE2-CE1 2.81Å; Q198-H469 PolarHBondContact NE2-ND1 3.24Å
199	W	88.5	Confident	87.7	Confident	146 Å²	146	49.4 Å²	49.4	55%	0.553	24%	0.242	S	C	*	.	H	α-helix	trans	-65	-41.9	179.1	-84.6	101.3	0	0	0	112.3	S195 F196 L202 L203 H469	S195-W199 PolarHBondContact O-N 3.39Å; S195-W199 VanDerWaalsContact O-N 3.14Å; F196-W199 PolarHBondContact O-N 3.33Å; W199-L202 PolarHBondContact O-N 2.92Å; W199-L203 WeakPolarHBondContact O-CB 3.5Å; W199-L203 PolarHBondContact O-N 2.93Å; W199-H469 AromaticContact CE2-NE2 3.7Å; W199-H469 AromaticContact CZ2-NE2 3.82Å
200	S	90.6	Very high	88	Confident	21 Å²	21	52.2 Å²	52.2	15%	0.147	26%	0.257	C	S	.	.	H	α-helix	trans	-66.6	-44.5	179	-176.1	0	0	0	0	111.6	F196 L202 L203 F204 Y521	F196-S200 WeakPolarHBondContact O-CB 3.1Å; F196-S200 PolarHBondContact O-N 3.01Å; S200-L202 PolarHBondContact O-N 3.44Å; S200-L203 PolarHBondContact O-N 3.45Å; S200-F204 WeakPolarHBondContact O-CD2 3.26Å; S200-F204 PolarHBondContact O-N 2.78Å; S200-F204 VanDerWaalsContact O-N 3.1Å; S200-Y521 WeakPolarHBondContact CB-OH 3.05Å; S200-Y521 PolarHBondContact OG-OH 3.24Å
201	S	87.2	Confident	88.2	Confident	0 Å²	0	46.1 Å²	46.1	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-63.8	-40.9	175.8	62.8	0	0	0	0	111.6	G197 Q198 L203 S205 F517 Y521	G197-S201 WeakPolarHBondContact O-CB 3.14Å; G197-S201 PolarHBondContact O-N 2.92Å; G197-S201 PolarHBondContact O-OG 3.39Å; Q198-S201 PolarHBondContact O-OG 2.76Å; S201-L203 PolarHBondContact O-N 3.45Å; S201-S205 VanDerWaalsContact O-CB 3.29Å; S201-S205 WeakPolarHBondContact O-CB 3.12Å; S201-S205 PolarHBondContact O-N 3.37Å; S201-F517 WeakPolarHBondContact O-CE2 3.42Å; S201-F517 WeakPolarHBondContact O-CZ 3.34Å; S201-Y521 PolarHBondContact N-OH 3.2Å; S201-Y521 VanDerWaalsContact N-OH 3.1Å
202	L	86.6	Confident	88.4	Confident	17 Å²	17	43 Å²	43	9%	0.089	23%	0.225	C	C	.	.	H	α-helix	trans	-58.6	-48.4	174.2	179.9	65.2	0	0	0	111.8	Q198 W199 S200 S205 L206 Q465 H469	Q198-L202 WeakPolarHBondContact O-CB 3.33Å; Q198-L202 PolarHBondContact O-N 3.41Å; W199-L202 PolarHBondContact O-N 2.92Å; S200-L202 PolarHBondContact O-N 3.44Å; L202-S205 PolarHBondContact O-N 3Å; L202-L206 HydrophobicContact CD1-CD1 4.01Å; L202-L206 HydrophobicContact CD1-CG 4.16Å; L202-L206 HydrophobicContact CG-CD1 3.87Å; L202-L206 HydrophobicContact CG-CG 4.41Å; L202-L206 VanDerWaalsContact O-CG 3.3Å; L202-L206 WeakPolarHBondContact O-CG 3.4Å; L202-L206 PolarHBondContact O-N 3.46Å; L202-Q465 HydrophobicContact CD1-CB 3.91Å; L202-Q465 WeakPolarHBondContact CD1-O 3.39Å; L202-H469 HydrophobicContact CD2-CB 3.83Å; L202-H469 WeakPolarHBondContact CD2-CD2 3.34Å
203	L	90.4	Very high	88.6	Confident	104 Å²	104	41.5 Å²	41.5	55%	0.545	22%	0.219	S	C	.	.	H	α-helix	trans	-57.3	-54	-179.9	178.4	65.7	0	0	0	111.8	W199 S200 S201 S205 L206 V207	W199-L203 WeakPolarHBondContact O-CB 3.5Å; W199-L203 PolarHBondContact O-N 2.93Å; S200-L203 PolarHBondContact O-N 3.45Å; S201-L203 PolarHBondContact O-N 3.45Å; L203-S205 VanDerWaalsContact C-N 3.26Å; L203-S205 PolarHBondContact O-N 3.41Å; L203-L206 PolarHBondContact O-N 2.95Å; L203-V207 WeakPolarHBondContact O-CG2 3.37Å; L203-V207 PolarHBondContact O-N 2.87Å
204	F	90	Very high	88.9	Confident	50 Å²	50	40.4 Å²	40.4	22%	0.219	22%	0.216	C	C	.	.	H	α-helix	trans	-66.4	-28.2	-178.5	-74	-70.1	0	0	0	112.7	S200 S208 A512 A516 F517	S200-F204 WeakPolarHBondContact O-CD2 3.26Å; S200-F204 PolarHBondContact O-N 2.78Å; S200-F204 VanDerWaalsContact O-N 3.1Å; F204-S208 PolarHBondContact O-N 3.38Å; F204-A512 WeakPolarHBondContact CD1-O 3.46Å; F204-A516 HydrophobicContact CB-CB 3.71Å; F204-A516 HydrophobicContact CD1-CB 3.85Å; F204-A516 HydrophobicContact CD2-CB 3.3Å; F204-A516 HydrophobicContact CE1-CB 4.28Å; F204-A516 HydrophobicContact CE2-CB 3.81Å; F204-A516 HydrophobicContact CG-CB 3.34Å; F204-A516 HydrophobicContact CZ-CB 4.27Å; F204-F517 HydrophobicContact CB-CD2 3.81Å; F204-F517 HydrophobicContact CB-CE2 3.64Å
205	S	87.3	Confident	89.1	Confident	1 Å²	1	39 Å²	39	1%	0.007	20%	0.2	C	C	.	.	H	α-helix	trans	-70.2	-44.2	174.9	-175.7	0	0	0	0	110.7	S201 L202 L203 S208 L209 N374 Q465 F517	S201-S205 VanDerWaalsContact O-CB 3.29Å; S201-S205 WeakPolarHBondContact O-CB 3.12Å; S201-S205 PolarHBondContact O-N 3.37Å; L202-S205 PolarHBondContact O-N 3Å; L203-S205 VanDerWaalsContact C-N 3.26Å; L203-S205 PolarHBondContact O-N 3.41Å; S205-S208 WeakPolarHBondContact O-CB 3.37Å; S205-S208 PolarHBondContact O-N 2.88Å; S205-L209 WeakPolarHBondContact O-CG 3.49Å; S205-L209 PolarHBondContact O-N 2.88Å; S205-N374 WeakPolarHBondContact CA-ND2 2.84Å; S205-N374 VanDerWaalsContact CB-ND2 3.31Å; S205-N374 WeakPolarHBondContact CB-ND2 3.31Å; S205-N374 PolarHBondContact OG-ND2 3.32Å; S205-Q465 VanDerWaalsContact OG-CD 3.27Å; S205-Q465 PolarHBondContact OG-NE2 3.4Å; S205-Q465 VanDerWaalsContact OG-NE2 3.15Å; S205-Q465 PolarHBondContact OG-OE1 3.28Å; S205-F517 VanDerWaalsContact N-CE2 3.31Å
206	L	87.9	Confident	89.3	Confident	21 Å²	21	36.3 Å²	36.3	11%	0.11	18%	0.178	C	C	.	.	H	α-helix	trans	-63.7	-40.9	176.1	-70.9	170.2	0	0	0	111.9	L202 L203 S208 L209 I210 Q465 L466	L202-L206 HydrophobicContact CD1-CD1 4.01Å; L202-L206 HydrophobicContact CD1-CG 4.16Å; L202-L206 HydrophobicContact CG-CD1 3.87Å; L202-L206 HydrophobicContact CG-CG 4.41Å; L202-L206 VanDerWaalsContact O-CG 3.3Å; L202-L206 WeakPolarHBondContact O-CG 3.4Å; L202-L206 PolarHBondContact O-N 3.46Å; L203-L206 PolarHBondContact O-N 2.95Å; L206-S208 VanDerWaalsContact C-N 3.27Å; L206-S208 PolarHBondContact O-N 3.42Å; L206-L209 PolarHBondContact O-N 3.18Å; L206-I210 HydrophobicContact CB-CD1 4.42Å; L206-I210 VanDerWaalsContact O-CB 3.3Å; L206-I210 WeakPolarHBondContact O-CB 3.29Å; L206-I210 VanDerWaalsContact O-CG1 3.26Å; L206-I210 WeakPolarHBondContact O-CG1 3.34Å; L206-I210 PolarHBondContact O-N 3.02Å; L206-Q465 HydrophobicContact CD2-CB 4.38Å; L206-L466 HydrophobicContact CD1-CD1 3.51Å; L206-L466 HydrophobicContact CD2-CB 4.12Å; L206-L466 HydrophobicContact CD2-CD1 4.46Å
207	V	90.9	Very high	89.6	Confident	53 Å²	53	28.7 Å²	28.7	32%	0.321	15%	0.145	S	C	.	.	H	α-helix	trans	-55.8	-45.1	173.6	170	0	0	0	0	110.6	L203 G211 A512	L203-V207 WeakPolarHBondContact O-CG2 3.37Å; L203-V207 PolarHBondContact O-N 2.87Å; V207-G211 PolarHBondContact O-N 3.19Å; V207-A512 HydrophobicContact CG1-CB 4.41Å
208	S	88.1	Confident	90	Very high	3 Å²	3	29 Å²	29	2%	0.021	15%	0.146	C	C	.	.	H	α-helix	trans	-65.5	-44.5	178.1	-163.6	0	0	0	0	113.2	F204 S205 L206 A212 F371 C513	F204-S208 PolarHBondContact O-N 3.38Å; S205-S208 WeakPolarHBondContact O-CB 3.37Å; S205-S208 PolarHBondContact O-N 2.88Å; L206-S208 VanDerWaalsContact C-N 3.27Å; L206-S208 PolarHBondContact O-N 3.42Å; S208-A212 WeakPolarHBondContact O-CB 3.4Å; S208-A212 PolarHBondContact O-N 3.45Å; S208-F371 WeakPolarHBondContact OG-CD1 3.49Å; S208-F371 WeakPolarHBondContact OG-CE1 3.42Å; S208-C513 PolarHBondContact OG-SG 3.2Å
209	L	88	Confident	90.4	Very high	20 Å²	20	27.9 Å²	27.9	11%	0.105	14%	0.141	C	C	.	.	H	α-helix	trans	-68.6	-46.6	-177.8	-71.6	175.1	0	0	0	111.5	S205 L206 G211 A212 M213 L458 L461 A462	S205-L209 WeakPolarHBondContact O-CG 3.49Å; S205-L209 PolarHBondContact O-N 2.88Å; L206-L209 PolarHBondContact O-N 3.18Å; L209-G211 VanDerWaalsContact C-N 3.35Å; L209-A212 PolarHBondContact O-N 3.01Å; L209-M213 VanDerWaalsContact O-CG 3.32Å; L209-M213 WeakPolarHBondContact O-CG 3.27Å; L209-M213 PolarHBondContact O-N 2.91Å; L209-L458 HydrophobicContact CD2-CD2 4.33Å; L209-L461 HydrophobicContact CD1-CB 4.31Å; L209-L461 HydrophobicContact CD2-CB 4.5Å; L209-A462 HydrophobicContact CB-CB 4.38Å; L209-A462 HydrophobicContact CD1-CB 4.21Å
210	I	90.8	Very high	90.6	Very high	59 Å²	59	21 Å²	21	30%	0.303	12%	0.115	S	C	.	.	H	α-helix	trans	-64.3	-42.6	177.3	-64.9	169.4	0	0	0	109.8	L206 A212 M213 I214	L206-I210 HydrophobicContact CB-CD1 4.42Å; L206-I210 VanDerWaalsContact O-CB 3.3Å; L206-I210 WeakPolarHBondContact O-CB 3.29Å; L206-I210 VanDerWaalsContact O-CG1 3.26Å; L206-I210 WeakPolarHBondContact O-CG1 3.34Å; L206-I210 PolarHBondContact O-N 3.02Å; I210-A212 PolarHBondContact O-N 2.73Å; I210-M213 PolarHBondContact O-N 3.46Å; I210-I214 HydrophobicContact CG2-CD1 3.89Å; I210-I214 HydrophobicContact CG2-CG1 4.38Å; I210-I214 VanDerWaalsContact O-CG1 3.31Å; I210-I214 WeakPolarHBondContact O-CG1 3.26Å; I210-I214 PolarHBondContact O-N 2.8Å
211	G	91.1	Very high	90.7	Very high	7 Å²	7	20.1 Å²	20.1	7%	0.072	11%	0.109	C	C	.	.	H	α-helix	trans	-58.2	-45.6	175.1	0	0	0	0	0	112.7	V207 L209 M213 I214 V215	V207-G211 PolarHBondContact O-N 3.19Å; L209-G211 VanDerWaalsContact C-N 3.35Å; G211-M213 PolarHBondContact O-N 3.29Å; G211-I214 PolarHBondContact O-N 2.74Å; G211-V215 WeakPolarHBondContact O-CG2 3.39Å; G211-V215 PolarHBondContact O-N 3.39Å
212	A	89.6	Confident	90.9	Very high	21 Å²	21	20.3 Å²	20.3	17%	0.174	11%	0.11	C	C	.	.	H	α-helix	trans	-62.1	-42.3	174.8	0	0	0	0	0	112.2	S208 L209 I210 I214 V215 Y216 L458	S208-A212 WeakPolarHBondContact O-CB 3.4Å; S208-A212 PolarHBondContact O-N 3.45Å; L209-A212 PolarHBondContact O-N 3.01Å; I210-A212 PolarHBondContact O-N 2.73Å; A212-I214 PolarHBondContact O-N 3Å; A212-V215 PolarHBondContact O-N 3.43Å; A212-Y216 WeakPolarHBondContact O-CB 3.3Å; A212-Y216 WeakPolarHBondContact O-CD1 3.23Å; A212-Y216 PolarHBondContact O-N 3.17Å; A212-L458 HydrophobicContact CB-CD1 4.32Å
213	M	92.1	Very high	91.2	Very high	1 Å²	1	19.5 Å²	19.5	1%	0.005	11%	0.106	C	C	.	.	H	α-helix	trans	-62.6	-41.4	176.4	-71.8	-176.7	78	0	0	111.9	L209 I210 G211 Y216 W217 L303 Y455 L458 I488	L209-M213 VanDerWaalsContact O-CG 3.32Å; L209-M213 WeakPolarHBondContact O-CG 3.27Å; L209-M213 PolarHBondContact O-N 2.91Å; I210-M213 PolarHBondContact O-N 3.46Å; G211-M213 PolarHBondContact O-N 3.29Å; M213-Y216 PolarHBondContact O-N 3.08Å; M213-W217 PolarHBondContact O-N 3.4Å; M213-L303 HydrophobicContact CE-CD2 4.09Å; M213-Y455 HydrophobicContact CB-CD2 4.36Å; M213-Y455 HydrophobicContact CB-CE2 3.68Å; M213-Y455 HydrophobicContact CE-CD1 4.44Å; M213-Y455 HydrophobicContact CE-CD2 4.25Å; M213-Y455 HydrophobicContact CE-CE1 3.94Å; M213-Y455 HydrophobicContact CE-CE2 3.7Å; M213-Y455 HydrophobicContact CG-CD2 4.33Å; M213-Y455 HydrophobicContact CG-CE2 4Å; M213-Y455 WeakPolarHBondContact O-CE2 3.41Å; M213-L458 HydrophobicContact CG-CB 3.91Å; M213-L458 HydrophobicContact CG-CD1 4.46Å; M213-L458 HydrophobicContact SD-CB 4.25Å; M213-I488 HydrophobicContact CB-CG2 4.14Å; M213-I488 HydrophobicContact CE-CG2 3.42Å; M213-I488 VanDerWaalsContact CE-CG2 3.42Å; M213-I488 HydrophobicContact SD-CD1 4.48Å; M213-I488 HydrophobicContact SD-CG2 3.66Å
214	I	93.6	Very high	91.3	Very high	28 Å²	28	16.3 Å²	16.3	14%	0.144	9%	0.089	C	C	.	.	H	α-helix	trans	-61.2	-48.7	174.9	-68.9	167.2	0	0	0	110.7	I210 G211 A212 Y216 W217 V218 A491 M495 I505	I210-I214 HydrophobicContact CG2-CD1 3.89Å; I210-I214 HydrophobicContact CG2-CG1 4.38Å; I210-I214 VanDerWaalsContact O-CG1 3.31Å; I210-I214 WeakPolarHBondContact O-CG1 3.26Å; I210-I214 PolarHBondContact O-N 2.8Å; G211-I214 PolarHBondContact O-N 2.74Å; A212-I214 PolarHBondContact O-N 3Å; I214-Y216 VanDerWaalsContact C-N 3.28Å; I214-Y216 PolarHBondContact O-N 2.71Å; I214-W217 WeakPolarHBondContact O-CB 3.31Å; I214-W217 PolarHBondContact O-N 3.41Å; I214-W217 VanDerWaalsContact O-N 3.08Å; I214-V218 WeakPolarHBondContact O-CG2 3.42Å; I214-V218 PolarHBondContact O-N 3.37Å; I214-A491 HydrophobicContact CD1-CB 4.35Å; I214-A491 HydrophobicContact CG1-CB 4.48Å; I214-M495 HydrophobicContact CG2-CB 3.58Å; I214-M495 HydrophobicContact CG2-CG 3.61Å; I214-I505 HydrophobicContact CG2-CD1 4.14Å; I214-I505 HydrophobicContact CG2-CG2 4.26Å
215	V	92.6	Very high	91.3	Very high	2 Å²	2	15.9 Å²	15.9	1%	0.012	9%	0.087	C	C	.	.	H	α-helix	trans	-58.7	-42.2	178.1	169.8	0	0	0	0	111.3	G211 A212 W217 V218 L219 I502 I505 I506	G211-V215 WeakPolarHBondContact O-CG2 3.39Å; G211-V215 PolarHBondContact O-N 3.39Å; A212-V215 PolarHBondContact O-N 3.43Å; V215-W217 VanDerWaalsContact C-N 3.31Å; V215-W217 PolarHBondContact O-N 2.97Å; V215-V218 PolarHBondContact O-N 3.35Å; V215-L219 HydrophobicContact CG1-CD1 3.76Å; V215-L219 WeakPolarHBondContact O-CB 3.47Å; V215-L219 PolarHBondContact O-N 2.81Å; V215-I502 HydrophobicContact CG1-CG2 4.25Å; V215-I505 HydrophobicContact CG2-CB 3.92Å; V215-I505 HydrophobicContact CG2-CG2 3.46Å; V215-I505 VanDerWaalsContact CG2-CG2 3.46Å; V215-I506 HydrophobicContact CG1-CD1 4.05Å; V215-I506 HydrophobicContact CG1-CG1 4.03Å; V215-I506 HydrophobicContact CG2-CG1 3.68Å
216	Y	92.4	Very high	91.4	Very high	25 Å²	25	16.4 Å²	16.4	10%	0.098	9%	0.09	C	C	.	.	H	α-helix	trans	-62.3	-41.4	176.9	-83.9	38.6	0	0	0	110.6	T133 A212 M213 I214 L219 M220 M451 V454 Y455 L458	T133-Y216 HydrophobicContact CG2-CD1 3.63Å; T133-Y216 HydrophobicContact CG2-CE1 3.43Å; T133-Y216 VanDerWaalsContact CG2-CE1 3.43Å; T133-Y216 HydrophobicContact CG2-CG 4.43Å; T133-Y216 WeakPolarHBondContact OG1-CE1 3.45Å; A212-Y216 WeakPolarHBondContact O-CB 3.3Å; A212-Y216 WeakPolarHBondContact O-CD1 3.23Å; A212-Y216 PolarHBondContact O-N 3.17Å; M213-Y216 PolarHBondContact O-N 3.08Å; I214-Y216 VanDerWaalsContact C-N 3.28Å; I214-Y216 PolarHBondContact O-N 2.71Å; Y216-L219 PolarHBondContact O-N 3.16Å; Y216-M220 VanDerWaalsContact O-CB 3.27Å; Y216-M220 WeakPolarHBondContact O-CB 3.22Å; Y216-M220 WeakPolarHBondContact O-CE 3.2Å; Y216-M220 WeakPolarHBondContact O-CG 3.48Å; Y216-M220 PolarHBondContact O-N 3.33Å; Y216-M451 HydrophobicContact CD2-CB 4.19Å; Y216-M451 HydrophobicContact CD2-CG 4.21Å; Y216-M451 HydrophobicContact CE2-CG 4.29Å; Y216-V454 HydrophobicContact CE2-CB 3.96Å; Y216-V454 HydrophobicContact CE2-CG1 3.65Å; Y216-Y455 HydrophobicContact CD2-CD2 4.5Å; Y216-L458 HydrophobicContact CD2-CD1 4.24Å; Y216-L458 HydrophobicContact CE2-CD1 3.98Å
217	W	94.4	Very high	91.5	Very high	0 Å²	0	16 Å²	16	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-61.5	-45.5	177.6	-157.3	-87.6	0	0	0	112.4	M213 I214 V215 M220 S221 P292 L295 V296 L299 Y455 V489 G492 V493	M213-W217 PolarHBondContact O-N 3.4Å; I214-W217 WeakPolarHBondContact O-CB 3.31Å; I214-W217 PolarHBondContact O-N 3.41Å; I214-W217 VanDerWaalsContact O-N 3.08Å; V215-W217 VanDerWaalsContact C-N 3.31Å; V215-W217 PolarHBondContact O-N 2.97Å; W217-M220 HydrophobicContact CE3-CE 4.28Å; W217-S221 WeakPolarHBondContact O-CB 3.32Å; W217-S221 PolarHBondContact O-N 2.94Å; W217-S221 PolarHBondContact O-OG 3.45Å; W217-P292 WeakPolarHBondContact CZ2-O 3.47Å; W217-P292 PolarHBondContact NE1-O 3.34Å; W217-L295 HydrophobicContact CH2-CB 4Å; W217-L295 HydrophobicContact CZ2-CB 3.65Å; W217-V296 HydrophobicContact CH2-CG2 4.08Å; W217-V296 HydrophobicContact CZ2-CB 4.49Å; W217-V296 HydrophobicContact CZ2-CG2 3.63Å; W217-L299 HydrophobicContact CE3-CD1 3.97Å; W217-L299 HydrophobicContact CH2-CB 4.15Å; W217-L299 HydrophobicContact CH2-CD1 3.96Å; W217-L299 HydrophobicContact CZ3-CB 3.96Å; W217-L299 HydrophobicContact CZ3-CD1 3.45Å; W217-L299 VanDerWaalsContact CZ3-CD1 3.45Å; W217-L299 HydrophobicContact CZ3-CG 4.33Å; W217-Y455 AromaticContact CE3-CE1 3.92Å; W217-Y455 HydrophobicContact CE3-CE1 3.92Å; W217-Y455 AromaticContact CE3-CE2 3.99Å; W217-Y455 HydrophobicContact CE3-CE2 3.99Å; W217-Y455 AromaticContact CE3-CZ 3.47Å; W217-Y455 VanDerWaalsContact CE3-CZ 3.47Å; W217-Y455 VanDerWaalsContact CE3-OH 3.28Å; W217-Y455 AromaticContact CZ3-CE1 3.68Å; W217-Y455 HydrophobicContact CZ3-CE1 3.68Å; W217-Y455 AromaticContact CZ3-CZ 3.71Å; W217-V489 HydrophobicContact CH2-CB 4.49Å; W217-V489 HydrophobicContact CH2-CG1 3.57Å; W217-V489 HydrophobicContact CH2-CG2 4.29Å; W217-V489 HydrophobicContact CZ2-CG1 3.92Å; W217-V489 HydrophobicContact CZ3-CG1 4.05Å; W217-V489 HydrophobicContact CZ3-CG2 4.04Å; W217-G492 VanDerWaalsContact CD1-C 3.44Å; W217-V493 HydrophobicContact CZ2-CG2 3.74Å
218	V	92.9	Very high	91.4	Very high	6 Å²	6	14.1 Å²	14.1	4%	0.036	8%	0.079	C	C	.	.	H	α-helix	trans	-62.4	-46.5	177.8	178	0	0	0	0	111	I214 V215 S221 N222 A496 P500 I502 I505	I214-V218 WeakPolarHBondContact O-CG2 3.42Å; I214-V218 PolarHBondContact O-N 3.37Å; V215-V218 PolarHBondContact O-N 3.35Å; V218-S221 PolarHBondContact O-N 3.32Å; V218-N222 PolarHBondContact O-N 3.43Å; V218-A496 HydrophobicContact CG2-CB 4.11Å; V218-P500 HydrophobicContact CG1-CB 4.06Å; V218-I502 HydrophobicContact CG1-CD1 4.38Å; V218-I502 HydrophobicContact CG1-CG1 3.75Å; V218-I505 HydrophobicContact CG2-CD1 4.15Å
219	L	92.7	Very high	91.2	Very high	1 Å²	1	16.6 Å²	16.6	1%	0.005	9%	0.09	C	C	.	.	H	α-helix	trans	-68.3	-43.3	-179.9	-79.1	167.9	0	0	0	112.7	T133 L136 V215 Y216 S221 N222 F223 N428 M451 I502	T133-L219 HydrophobicContact CG2-CD1 3.27Å; L136-L219 HydrophobicContact CD1-CD2 4.23Å; V215-L219 HydrophobicContact CG1-CD1 3.76Å; V215-L219 WeakPolarHBondContact O-CB 3.47Å; V215-L219 PolarHBondContact O-N 2.81Å; Y216-L219 PolarHBondContact O-N 3.16Å; L219-S221 VanDerWaalsContact C-N 3.27Å; L219-S221 PolarHBondContact O-N 3.23Å; L219-N222 PolarHBondContact O-N 3.11Å; L219-F223 HydrophobicContact CB-CE2 4.17Å; L219-F223 HydrophobicContact CD2-CE2 4.43Å; L219-F223 HydrophobicContact CD2-CZ 4.08Å; L219-F223 VanDerWaalsContact O-CD2 3.27Å; L219-F223 WeakPolarHBondContact O-CD2 3.27Å; L219-F223 VanDerWaalsContact O-CG 3.29Å; L219-F223 WeakPolarHBondContact O-CG 3.39Å; L219-F223 PolarHBondContact O-N 2.83Å; L219-N428 HydrophobicContact CD2-CB 4.38Å; L219-M451 HydrophobicContact CB-SD 3.98Å; L219-I502 HydrophobicContact CD1-CG2 4.34Å; L219-I502 HydrophobicContact CD2-CD1 3.45Å; L219-I502 VanDerWaalsContact CD2-CD1 3.45Å; L219-I502 HydrophobicContact CD2-CG1 4.22Å; L219-I502 HydrophobicContact CG-CD1 4Å; L219-I502 HydrophobicContact CG-CG1 4.24Å; L219-I502 HydrophobicContact CG-CG2 4.48Å
220	M	93.7	Very high	91.2	Very high	0 Å²	0	17 Å²	17	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-59.7	-40.5	174.2	-73.2	-174.4	-65.3	0	0	111.1	Y216 W217 F223 L224 L295 L299 L448 M451 M452 Y455	Y216-M220 VanDerWaalsContact O-CB 3.27Å; Y216-M220 WeakPolarHBondContact O-CB 3.22Å; Y216-M220 WeakPolarHBondContact O-CE 3.2Å; Y216-M220 WeakPolarHBondContact O-CG 3.48Å; Y216-M220 PolarHBondContact O-N 3.33Å; W217-M220 HydrophobicContact CE3-CE 4.28Å; M220-F223 PolarHBondContact O-N 2.98Å; M220-L224 WeakPolarHBondContact O-CB 3.48Å; M220-L224 PolarHBondContact O-N 3.45Å; M220-L295 HydrophobicContact CB-CD1 3.78Å; M220-L295 HydrophobicContact CB-CD2 4.49Å; M220-L299 HydrophobicContact CE-CD1 3.42Å; M220-L299 VanDerWaalsContact CE-CD1 3.42Å; M220-L299 HydrophobicContact SD-CD1 3.87Å; M220-L448 HydrophobicContact CB-CD1 3.89Å; M220-L448 HydrophobicContact CG-CD1 3.98Å; M220-M451 HydrophobicContact CG-CB 3.56Å; M220-M451 HydrophobicContact CG-SD 4.31Å; M220-M451 HydrophobicContact SD-CB 3.76Å; M220-M452 HydrophobicContact SD-CG 4.12Å; M220-Y455 HydrophobicContact CE-CD2 3.91Å; M220-Y455 HydrophobicContact CE-CE2 4.39Å; M220-Y455 HydrophobicContact CE-CG 4.02Å
221	S	93.1	Very high	91	Very high	3 Å²	3	18.1 Å²	18.1	2%	0.021	10%	0.097	C	C	.	.	H	α-helix	trans	-62.4	-44.4	175.8	-57.6	0	0	0	0	111.1	W217 V218 L219 L224 F225 V291 L295	W217-S221 WeakPolarHBondContact O-CB 3.32Å; W217-S221 PolarHBondContact O-N 2.94Å; W217-S221 PolarHBondContact O-OG 3.45Å; V218-S221 PolarHBondContact O-N 3.32Å; L219-S221 VanDerWaalsContact C-N 3.27Å; L219-S221 PolarHBondContact O-N 3.23Å; S221-L224 PolarHBondContact O-N 2.96Å; S221-F225 VanDerWaalsContact O-CB 3.27Å; S221-F225 WeakPolarHBondContact O-CB 3.33Å; S221-F225 PolarHBondContact O-N 3.31Å; S221-V291 WeakPolarHBondContact O-CG1 3.27Å; S221-L295 WeakPolarHBondContact OG-CD1 3.37Å
222	N	91.3	Very high	90.7	Very high	5 Å²	5	19.1 Å²	19.1	3%	0.027	10%	0.099	C	C	.	.	H	α-helix	trans	-63.9	-43.2	177.7	-170.6	25.4	0	0	0	112.7	V218 L219 N226 K287 N428 D431	V218-N222 PolarHBondContact O-N 3.43Å; L219-N222 PolarHBondContact O-N 3.11Å; N222-N226 WeakPolarHBondContact O-CB 3.49Å; N222-N226 PolarHBondContact O-N 3.09Å; N222-N226 PolarHBondContact O-ND2 3.23Å; N222-N226 PolarHBondContact OD1-ND2 3.15Å; N222-K287 VanDerWaalsContact OD1-CE 3.29Å; N222-K287 WeakPolarHBondContact OD1-CE 3.29Å; N222-K287 PolarHBondContact OD1-NZ 2.99Å; N222-K287 VanDerWaalsContact OD1-NZ 3.1Å; N222-N428 PolarHBondContact ND2-ND2 2.76Å; N222-D431 VanDerWaalsContact ND2-CG 3.27Å; N222-D431 PolarHBondContact ND2-OD1 3.14Å; N222-D431 PolarHBondContact ND2-OD2 3.38Å
223	F	92.7	Very high	90.4	Very high	0 Å²	0	18.7 Å²	18.7	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-69.6	-41	177.8	-62.6	-32.2	0	0	0	112.4	L136 L219 M220 N226 T227 L430 R444 L447 L448 M451	L136-F223 HydrophobicContact CD1-CE2 4.4Å; L136-F223 HydrophobicContact CD1-CZ 3.68Å; L219-F223 HydrophobicContact CB-CE2 4.17Å; L219-F223 HydrophobicContact CD2-CE2 4.43Å; L219-F223 HydrophobicContact CD2-CZ 4.08Å; L219-F223 VanDerWaalsContact O-CD2 3.27Å; L219-F223 WeakPolarHBondContact O-CD2 3.27Å; L219-F223 VanDerWaalsContact O-CG 3.29Å; L219-F223 WeakPolarHBondContact O-CG 3.39Å; L219-F223 PolarHBondContact O-N 2.83Å; M220-F223 PolarHBondContact O-N 2.98Å; F223-N226 PolarHBondContact O-N 3.45Å; F223-T227 VanDerWaalsContact O-CB 3.25Å; F223-T227 WeakPolarHBondContact O-CB 3.3Å; F223-T227 PolarHBondContact O-N 2.98Å; F223-T227 PolarHBondContact O-OG1 3.22Å; F223-L430 HydrophobicContact CE1-CD1 4.08Å; F223-L430 HydrophobicContact CZ-CD1 4.36Å; F223-R444 HydrophobicContact CB-CB 4.35Å; F223-R444 HydrophobicContact CD1-CB 4.08Å; F223-R444 HydrophobicContact CD1-CG 3.71Å; F223-R444 HydrophobicContact CE1-CG 4.13Å; F223-R444 HydrophobicContact CG-CB 4.36Å; F223-R444 HydrophobicContact CG-CG 4.47Å; F223-L447 HydrophobicContact CD2-CB 4.2Å; F223-L447 HydrophobicContact CE2-CB 3.8Å; F223-L447 HydrophobicContact CE2-CD1 4.34Å; F223-L447 HydrophobicContact CZ-CB 4.33Å; F223-L447 HydrophobicContact CZ-CD1 4.05Å; F223-L448 HydrophobicContact CB-CB 4.18Å; F223-L448 HydrophobicContact CB-CD1 4.4Å; F223-M451 HydrophobicContact CD2-CE 4.46Å; F223-M451 HydrophobicContact CD2-SD 4.18Å; F223-M451 HydrophobicContact CE2-CE 3.6Å; F223-M451 HydrophobicContact CE2-SD 3.78Å; F223-M451 HydrophobicContact CZ-CE 4.47Å
224	L	92.1	Very high	90	Very high	37 Å²	37	25.6 Å²	25.6	19%	0.194	12%	0.124	C	C	.	.	H	α-helix	trans	-63.5	-44.7	176.3	-177.6	60.4	0	0	0	110.9	M220 S221 N226 T227 G228 W285 V291 L295 L448	M220-L224 WeakPolarHBondContact O-CB 3.48Å; M220-L224 PolarHBondContact O-N 3.45Å; S221-L224 PolarHBondContact O-N 2.96Å; L224-N226 PolarHBondContact O-N 2.96Å; L224-T227 PolarHBondContact O-N 3.13Å; L224-G228 PolarHBondContact O-N 2.76Å; L224-W285 HydrophobicContact CD1-CH2 4.5Å; L224-W285 HydrophobicContact CD1-CZ2 4.4Å; L224-W285 HydrophobicContact CG-CH2 4.47Å; L224-W285 HydrophobicContact CG-CZ2 4.22Å; L224-V291 HydrophobicContact CB-CG1 3.93Å; L224-V291 HydrophobicContact CD2-CG1 3.85Å; L224-V291 HydrophobicContact CG-CG1 3.94Å; L224-L295 HydrophobicContact CD2-CD2 3.68Å; L224-L295 HydrophobicContact CD2-CG 3.9Å; L224-L448 HydrophobicContact CB-CD2 4.39Å; L224-L448 HydrophobicContact CD1-CD2 4.26Å
225	F	91	Very high	89.5	Confident	40 Å²	40	29.2 Å²	29.2	18%	0.175	14%	0.143	C	C	.	.	H	α-helix	trans	-56.1	-53.7	175.8	170.8	-103	0	0	0	111.2	S221 T227 G228 K229 W285 K287 V291	S221-F225 VanDerWaalsContact O-CB 3.27Å; S221-F225 WeakPolarHBondContact O-CB 3.33Å; S221-F225 PolarHBondContact O-N 3.31Å; F225-T227 VanDerWaalsContact C-N 3.32Å; F225-T227 PolarHBondContact O-N 3.26Å; F225-G228 PolarHBondContact O-N 2.95Å; F225-K229 HydrophobicContact CE1-CD 4.47Å; F225-K229 HydrophobicContact CZ-CD 4.38Å; F225-K229 WeakPolarHBondContact O-CB 3.37Å; F225-K229 PolarHBondContact O-N 3.48Å; F225-W285 AromaticContact CD2-CD1 3.7Å; F225-W285 VanDerWaalsContact CE2-O 3.26Å; F225-W285 WeakPolarHBondContact CE2-O 3.23Å; F225-W285 PolarHBondContact O-NE1 3.27Å; F225-W285 VanDerWaalsContact O-NE1 3.14Å; F225-K287 HydrophobicContact CB-CB 4.41Å; F225-K287 HydrophobicContact CB-CG 4.42Å; F225-K287 HydrophobicContact CD1-CB 3.95Å; F225-K287 HydrophobicContact CD1-CD 4.09Å; F225-K287 HydrophobicContact CD1-CG 4.1Å; F225-K287 HydrophobicContact CD2-CB 3.8Å; F225-K287 HydrophobicContact CE1-CB 4.14Å; F225-K287 HydrophobicContact CE1-CD 4.33Å; F225-K287 HydrophobicContact CE2-CB 4Å; F225-K287 HydrophobicContact CG-CB 3.77Å; F225-K287 HydrophobicContact CG-CG 4.13Å; F225-K287 HydrophobicContact CZ-CB 4.16Å; F225-V291 HydrophobicContact CB-CG1 4.29Å; F225-V291 HydrophobicContact CB-CG2 4.21Å; F225-V291 HydrophobicContact CD2-CG2 4.24Å
226	N	89.1	Confident	88.8	Confident	12 Å²	12	33.9 Å²	33.9	6%	0.064	16%	0.164	C	C	.	.	H	α-helix	trans	-63.6	-35.5	179.9	-86	-65	0	0	0	113.5	N222 F223 L224 K229 F230 S435 R444	N222-N226 WeakPolarHBondContact O-CB 3.49Å; N222-N226 PolarHBondContact O-N 3.09Å; N222-N226 PolarHBondContact O-ND2 3.23Å; N222-N226 PolarHBondContact OD1-ND2 3.15Å; F223-N226 PolarHBondContact O-N 3.45Å; L224-N226 PolarHBondContact O-N 2.96Å; N226-K229 PolarHBondContact O-N 3.46Å; N226-F230 PolarHBondContact O-N 2.85Å; N226-S435 PolarHBondContact OD1-OG 3.36Å; N226-R444 VanDerWaalsContact CG-NH1 3.34Å; N226-R444 PolarHBondContact OD1-NH1 3.47Å
227	T	89.7	Confident	87.9	Confident	13 Å²	13	40.6 Å²	40.6	8%	0.08	20%	0.196	C	C	.	.	H	α-helix	trans	-65.3	-46.5	176	-59.9	0	0	0	0	110.2	F223 L224 F225 F230 I231 F441 I445	F223-T227 VanDerWaalsContact O-CB 3.25Å; F223-T227 WeakPolarHBondContact O-CB 3.3Å; F223-T227 PolarHBondContact O-N 2.98Å; F223-T227 PolarHBondContact O-OG1 3.22Å; L224-T227 PolarHBondContact O-N 3.13Å; F225-T227 VanDerWaalsContact C-N 3.32Å; F225-T227 PolarHBondContact O-N 3.26Å; T227-F230 PolarHBondContact O-N 3.02Å; T227-I231 HydrophobicContact CG2-CD1 4.12Å; T227-I231 WeakPolarHBondContact O-CG1 3.4Å; T227-I231 PolarHBondContact O-N 3.01Å; T227-F441 HydrophobicContact CG2-CD2 4.47Å; T227-F441 HydrophobicContact CG2-CE2 3.62Å; T227-F441 HydrophobicContact CG2-CZ 4.28Å; T227-I445 HydrophobicContact CG2-CD1 4.17Å; T227-I445 HydrophobicContact CG2-CG1 3.99Å
228	G	88.1	Confident	86.7	Confident	13 Å²	13	43.7 Å²	43.7	13%	0.134	21%	0.212	C	C	.	.	H	α-helix	trans	-63.5	-41.2	175.8	0	0	0	0	0	112.6	L224 F225 F230 I231 F232	L224-G228 PolarHBondContact O-N 2.76Å; F225-G228 PolarHBondContact O-N 2.95Å; G228-F230 PolarHBondContact O-N 3.2Å; G228-I231 PolarHBondContact O-N 2.93Å; G228-F232 WeakPolarHBondContact O-CB 3.24Å; G228-F232 PolarHBondContact O-N 3.09Å
229	K	85.6	Confident	85.3	Confident	56 Å²	56	50 Å²	50	24%	0.243	25%	0.246	C	C	.	.	H	α-helix	trans	-61.2	-42.6	175.7	-170.3	173.9	-178.5	-173.1	0	112.1	F225 N226 F232 N233 D240	F225-K229 HydrophobicContact CE1-CD 4.47Å; F225-K229 HydrophobicContact CZ-CD 4.38Å; F225-K229 WeakPolarHBondContact O-CB 3.37Å; F225-K229 PolarHBondContact O-N 3.48Å; N226-K229 PolarHBondContact O-N 3.46Å; K229-F232 PolarHBondContact O-N 2.81Å; K229-N233 WeakPolarHBondContact O-CB 3.45Å; K229-N233 PolarHBondContact O-N 3.22Å; K229-N233 PolarHBondContact O-OD1 3.06Å; K229-D240 WeakPolarHBondContact CE-OD2 3.24Å; K229-D240 IonicContact NZ-OD2 3.84Å; K229-D240 PolarHBondContact NZ-OD2 3.36Å
230	F	86.4	Confident	83.6	Confident	28 Å²	28	52.8 Å²	52.8	12%	0.123	26%	0.26	C	S	.	.	H	α-helix	trans	-61.3	-47.7	174.4	178.6	-97.9	0	0	0	112.2	N226 T227 G228 F232 N233 F234 S435 S436 F441	N226-F230 PolarHBondContact O-N 2.85Å; T227-F230 PolarHBondContact O-N 3.02Å; G228-F230 PolarHBondContact O-N 3.2Å; F230-F232 VanDerWaalsContact C-N 3.33Å; F230-F232 PolarHBondContact O-N 3.49Å; F230-N233 PolarHBondContact O-N 3.26Å; F230-F234 VanDerWaalsContact O-CB 3.25Å; F230-F234 WeakPolarHBondContact O-CB 3.38Å; F230-F234 PolarHBondContact O-N 3.21Å; F230-S435 WeakPolarHBondContact CD2-O 3.27Å; F230-S436 WeakPolarHBondContact CE2-O 3.34Å; F230-F441 HydrophobicContact CB-CD2 3.61Å; F230-F441 HydrophobicContact CB-CE2 3.85Å; F230-F441 HydrophobicContact CB-CG 4.44Å; F230-F441 HydrophobicContact CD1-CB 4.45Å; F230-F441 AromaticContact CD1-CD1 3.86Å; F230-F441 HydrophobicContact CD1-CD1 3.86Å; F230-F441 AromaticContact CD1-CD2 3.35Å; F230-F441 HydrophobicContact CD1-CD2 3.35Å; F230-F441 AromaticContact CD1-CE1 3.8Å; F230-F441 HydrophobicContact CD1-CE1 3.8Å; F230-F441 AromaticContact CD1-CE2 3.26Å; F230-F441 HydrophobicContact CD1-CE2 3.26Å; F230-F441 AromaticContact CD1-CG 3.63Å; F230-F441 HydrophobicContact CD1-CG 3.63Å; F230-F441 AromaticContact CD1-CZ 3.49Å; F230-F441 HydrophobicContact CD1-CZ 3.49Å; F230-F441 VanDerWaalsContact CD1-CZ 3.49Å; F230-F441 HydrophobicContact CD2-CB 4.41Å; F230-F441 HydrophobicContact CD2-CD2 4.37Å; F230-F441 HydrophobicContact CD2-CG 4.4Å; F230-F441 AromaticContact CE1-CD1 3.69Å; F230-F441 HydrophobicContact CE1-CD1 3.69Å; F230-F441 HydrophobicContact CE1-CD2 4.06Å; F230-F441 AromaticContact CE1-CE1 3.7Å; F230-F441 HydrophobicContact CE1-CE1 3.7Å; F230-F441 HydrophobicContact CE1-CE2 4.06Å; F230-F441 AromaticContact CE1-CG 3.86Å; F230-F441 HydrophobicContact CE1-CG 3.86Å; F230-F441 AromaticContact CE1-CZ 3.87Å; F230-F441 HydrophobicContact CE1-CZ 3.87Å; F230-F441 HydrophobicContact CG-CB 4.33Å; F230-F441 AromaticContact CG-CD2 3.51Å; F230-F441 HydrophobicContact CG-CD2 3.51Å; F230-F441 AromaticContact CG-CE2 3.81Å; F230-F441 HydrophobicContact CG-CE2 3.81Å; F230-F441 AromaticContact CG-CG 3.89Å; F230-F441 HydrophobicContact CG-CG 3.89Å; F230-F441 HydrophobicContact CG-CZ 4.44Å; F230-F441 HydrophobicContact CZ-CD1 4.25Å; F230-F441 HydrophobicContact CZ-CG 4.32Å
231	I	86.9	Confident	81.8	Confident	82 Å²	82	55.6 Å²	55.6	42%	0.421	28%	0.278	S	S	.	.	H	α-helix	trans	-61.3	-44.2	179.8	-67.4	166.6	0	0	0	110.4	T227 G228 F234 I235 F441	T227-I231 HydrophobicContact CG2-CD1 4.12Å; T227-I231 WeakPolarHBondContact O-CG1 3.4Å; T227-I231 PolarHBondContact O-N 3.01Å; G228-I231 PolarHBondContact O-N 2.93Å; I231-F234 PolarHBondContact O-N 3.41Å; I231-I235 HydrophobicContact CG2-CD1 3.72Å; I231-I235 VanDerWaalsContact O-CG1 3.24Å; I231-I235 WeakPolarHBondContact O-CG1 3.25Å; I231-I235 PolarHBondContact O-N 3.4Å; I231-F441 HydrophobicContact CG1-CE2 4.39Å; I231-F441 HydrophobicContact CG1-CZ 4.36Å
232	F	85	Confident	79.6	Confident	28 Å²	28	62.4 Å²	62.4	12%	0.123	31%	0.314	C	S	.	.	H	α-helix	trans	-61.1	-51	176.9	-178.3	-96.3	0	0	0	111.6	G228 K229 F230 F234 I235 H236 I238 F281	G228-F232 WeakPolarHBondContact O-CB 3.24Å; G228-F232 PolarHBondContact O-N 3.09Å; K229-F232 PolarHBondContact O-N 2.81Å; F230-F232 VanDerWaalsContact C-N 3.33Å; F230-F232 PolarHBondContact O-N 3.49Å; F232-F234 VanDerWaalsContact C-N 3.27Å; F232-F234 PolarHBondContact O-N 2.87Å; F232-I235 PolarHBondContact O-N 3.23Å; F232-H236 AromaticContact CD2-CD2 3.43Å; F232-H236 VanDerWaalsContact CD2-CD2 3.43Å; F232-H236 WeakPolarHBondContact CD2-CD2 3.4Å; F232-H236 AromaticContact CD2-NE2 3.76Å; F232-H236 AromaticContact CE1-CD2 3.99Å; F232-H236 AromaticContact CE2-CD2 3.2Å; F232-H236 WeakPolarHBondContact CE2-CD2 3.45Å; F232-H236 AromaticContact CE2-NE2 3.3Å; F232-H236 VanDerWaalsContact CE2-NE2 3.3Å; F232-H236 WeakPolarHBondContact CE2-NE2 3.09Å; F232-H236 AromaticContact CG-CD2 3.92Å; F232-H236 AromaticContact CZ-CD2 3.51Å; F232-H236 AromaticContact CZ-NE2 3.89Å; F232-H236 PolarHBondContact O-CD2 3.41Å; F232-H236 PolarHBondContact O-N 3.23Å; F232-I238 HydrophobicContact CE1-CD1 3.87Å; F232-F281 HydrophobicContact CB-CD2 4.34Å; F232-F281 HydrophobicContact CB-CE1 4.06Å; F232-F281 HydrophobicContact CB-CE2 3.79Å; F232-F281 HydrophobicContact CB-CZ 3.62Å; F232-F281 AromaticContact CD1-CD1 3.89Å; F232-F281 HydrophobicContact CD1-CD1 3.89Å; F232-F281 AromaticContact CD1-CE1 3.99Å; F232-F281 HydrophobicContact CD1-CE1 3.99Å; F232-F281 HydrophobicContact CD1-CG 4.21Å; F232-F281 HydrophobicContact CD1-CZ 4.39Å; F232-F281 HydrophobicContact CD2-CB 4.23Å; F232-F281 HydrophobicContact CD2-CD1 4.19Å; F232-F281 AromaticContact CD2-CD2 3.49Å; F232-F281 HydrophobicContact CD2-CD2 3.49Å; F232-F281 VanDerWaalsContact CD2-CD2 3.49Å; F232-F281 HydrophobicContact CD2-CE1 4.46Å; F232-F281 AromaticContact CD2-CE2 3.81Å; F232-F281 HydrophobicContact CD2-CE2 3.81Å; F232-F281 AromaticContact CD2-CG 3.69Å; F232-F281 HydrophobicContact CD2-CG 3.69Å; F232-F281 HydrophobicContact CD2-CZ 4.28Å; F232-F281 HydrophobicContact CE1-CB 4.44Å; F232-F281 HydrophobicContact CE1-CD1 4.06Å; F232-F281 HydrophobicContact CE1-CG 4.23Å; F232-F281 HydrophobicContact CE2-CB 3.73Å; F232-F281 HydrophobicContact CE2-CD1 4.34Å; F232-F281 AromaticContact CE2-CD2 3.88Å; F232-F281 HydrophobicContact CE2-CD2 3.88Å; F232-F281 AromaticContact CE2-CG 3.72Å; F232-F281 HydrophobicContact CE2-CG 3.72Å; F232-F281 AromaticContact CG-CD1 3.96Å; F232-F281 HydrophobicContact CG-CD1 3.96Å; F232-F281 AromaticContact CG-CD2 3.9Å; F232-F281 HydrophobicContact CG-CD2 3.9Å; F232-F281 AromaticContact CG-CE1 3.91Å; F232-F281 HydrophobicContact CG-CE1 3.91Å; F232-F281 AromaticContact CG-CE2 3.85Å; F232-F281 HydrophobicContact CG-CE2 3.85Å; F232-F281 AromaticContact CG-CG 3.95Å; F232-F281 HydrophobicContact CG-CG 3.95Å; F232-F281 AromaticContact CG-CZ 3.85Å; F232-F281 HydrophobicContact CG-CZ 3.85Å; F232-F281 HydrophobicContact CZ-CB 3.85Å; F232-F281 HydrophobicContact CZ-CD1 4.29Å; F232-F281 AromaticContact CZ-CG 4Å; F232-F281 HydrophobicContact CZ-CG 4Å
233	N	83.2	Confident	77.8	Confident	13 Å²	13	68 Å²	68	7%	0.07	35%	0.349	C	S	.	.	H	α-helix	trans	-62.2	-35.6	179.2	-70.3	4.8	0	0	0	112	K229 F230 H237 I238 D240	K229-N233 WeakPolarHBondContact O-CB 3.45Å; K229-N233 PolarHBondContact O-N 3.22Å; K229-N233 PolarHBondContact O-OD1 3.06Å; F230-N233 PolarHBondContact O-N 3.26Å; N233-H237 WeakPolarHBondContact O-CA 3.2Å; N233-H237 PolarHBondContact O-N 3.46Å; N233-I238 PolarHBondContact O-N 2.97Å; N233-I238 VanDerWaalsContact O-N 3.09Å; N233-D240 PolarHBondContact ND2-OD2 3.45Å
234	F	82.9	Confident	76.3	Confident	146 Å²	146	71.4 Å²	71.4	64%	0.64	37%	0.366	S	S	*	.	H	α-helix	trans	-66.7	-41.4	176	-176	-95.9	0	0	0	112.3	F230 I231 F232	F230-F234 VanDerWaalsContact O-CB 3.25Å; F230-F234 WeakPolarHBondContact O-CB 3.38Å; F230-F234 PolarHBondContact O-N 3.21Å; I231-F234 PolarHBondContact O-N 3.41Å; F232-F234 VanDerWaalsContact C-N 3.27Å; F232-F234 PolarHBondContact O-N 2.87Å
235	I	84.2	Confident	74.6	Confident	104 Å²	104	74.8 Å²	74.8	53%	0.533	38%	0.384	S	S	.	.	H	α-helix	trans	-70.3	-39.7	178.4	-69	166.7	0	0	0	111.4	I231 F232	I231-I235 HydrophobicContact CG2-CD1 3.72Å; I231-I235 VanDerWaalsContact O-CG1 3.24Å; I231-I235 WeakPolarHBondContact O-CG1 3.25Å; I231-I235 PolarHBondContact O-N 3.4Å; F232-I235 PolarHBondContact O-N 3.23Å
236	H	78.1	Confident	73.1	Confident	100 Å²	100	74.4 Å²	74.4	46%	0.463	39%	0.386	S	S	.	.	H	α-helix	trans	-93.7	2.1	-175.9	-70.3	-74.8	0	0	0	114.2	F232 I238	F232-H236 AromaticContact CD2-CD2 3.43Å; F232-H236 VanDerWaalsContact CD2-CD2 3.43Å; F232-H236 WeakPolarHBondContact CD2-CD2 3.4Å; F232-H236 AromaticContact CD2-NE2 3.76Å; F232-H236 AromaticContact CE1-CD2 3.99Å; F232-H236 AromaticContact CE2-CD2 3.2Å; F232-H236 WeakPolarHBondContact CE2-CD2 3.45Å; F232-H236 AromaticContact CE2-NE2 3.3Å; F232-H236 VanDerWaalsContact CE2-NE2 3.3Å; F232-H236 WeakPolarHBondContact CE2-NE2 3.09Å; F232-H236 AromaticContact CG-CD2 3.92Å; F232-H236 AromaticContact CZ-CD2 3.51Å; F232-H236 AromaticContact CZ-NE2 3.89Å; F232-H236 PolarHBondContact O-CD2 3.41Å; F232-H236 PolarHBondContact O-N 3.23Å; H236-I238 VanDerWaalsContact C-N 3.29Å; H236-I238 HydrophobicContact CB-CD1 3.8Å; H236-I238 HydrophobicContact CB-CG1 3.88Å; H236-I238 PolarHBondContact O-N 3.31Å
237	H	73.8	Confident	71.7	Confident	166 Å²	166	74.4 Å²	74.4	77%	0.769	39%	0.386	S	S	*	.	T	Hydrogen-bonded Turn	trans	52.3	41.7	-178.2	-59.4	-62	0	0	0	113.9	N233	N233-H237 WeakPolarHBondContact O-CA 3.2Å; N233-H237 PolarHBondContact O-N 3.46Å
238	I	69.3	Low	70.2	Confident	65 Å²	65	81.7 Å²	81.7	33%	0.333	43%	0.425	S	S	.	.			trans	-93.8	122.9	-179.4	-57.8	172.6	0	0	0	110	F232 N233 H236	F232-I238 HydrophobicContact CE1-CD1 3.87Å; N233-I238 PolarHBondContact O-N 2.97Å; N233-I238 VanDerWaalsContact O-N 3.09Å; H236-I238 VanDerWaalsContact C-N 3.29Å; H236-I238 HydrophobicContact CB-CD1 3.8Å; H236-I238 HydrophobicContact CB-CG1 3.88Å; H236-I238 PolarHBondContact O-N 3.31Å
239	N	62.1	Low	68.9	Low	138 Å²	138	87.1 Å²	87.1	74%	0.738	45%	0.451	S	S	*	.			trans	-95.4	105.3	171.5	-82.9	-9.2	0	0	0	110.1	T241	N239-T241 VanDerWaalsContact C-N 3.26Å; N239-T241 PolarHBondContact O-N 2.9Å
240	D	57.6	Low	67.7	Low	59 Å²	59	90 Å²	90	32%	0.316	48%	0.478	S	S	.	.			trans	-83	22.6	-171.4	-111.6	-11.1	0	0	0	114.8	K229 N233 D242	K229-D240 WeakPolarHBondContact CE-OD2 3.24Å; K229-D240 IonicContact NZ-OD2 3.84Å; K229-D240 PolarHBondContact NZ-OD2 3.36Å; N233-D240 PolarHBondContact ND2-OD2 3.45Å; D240-D242 PolarHBondContact O-N 2.65Å
241	T	54.9	Low	66.9	Low	59 Å²	59	90.8 Å²	90.8	36%	0.362	48%	0.484	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.5	-8.1	-167.9	42.3	0	0	0	0	115.6	N239	N239-T241 VanDerWaalsContact C-N 3.26Å; N239-T241 PolarHBondContact O-N 2.9Å
242	D	48.8	Very low	66.5	Low	146 Å²	146	88.4 Å²	88.4	78%	0.781	47%	0.473	S	S	*	.	T	Hydrogen-bonded Turn	trans	-98.5	-7.6	-160.2	-60.8	-5.3	0	0	0	114.4	D240	D240-D242 PolarHBondContact O-N 2.65Å
243	T	52.3	Low	66.4	Low	124 Å²	124	87.2 Å²	87.2	76%	0.761	47%	0.468	S	S	*	.	S	Bend	trans	-107.4	-13.7	-173.9	52.7	0	0	0	0	115.5
244	I	60.4	Low	66.5	Low	71 Å²	71	87.7 Å²	87.7	36%	0.364	47%	0.47	S	S	.	.	S	Bend	trans	-122.7	136.3	-176	-57.7	175.3	0	0	0	109.4	S246 I254	I244-S246 PolarHBondContact O-N 3.15Å; I244-I254 HydrophobicContact CG2-CB 3.97Å; I244-I254 HydrophobicContact CG2-CG2 4.25Å
245	L	56.8	Low	66.6	Low	108 Å²	108	80.9 Å²	80.9	57%	0.565	44%	0.441	S	S	*	.			trans	-51.4	109.7	174.9	-169.3	76.2	0	0	0	109.7	C255 L420	L245-C255 PolarHBondContact O-N 3.3Å; L245-L420 HydrophobicContact CD2-CD2 3.57Å; L245-L420 HydrophobicContact CG-CD2 3.96Å
246	S	60.3	Low	66.2	Low	32 Å²	32	78.4 Å²	78.4	22%	0.224	43%	0.432	C	S	.	.	B	Isolated β-bridge	trans	-132.3	156	-174.9	70.4	0	0	0	0	110.9	I244 V253	I244-S246 PolarHBondContact O-N 3.15Å; S246-V253 WeakPolarHBondContact CA-O 3.44Å
247	T	59.9	Low	65.4	Low	12 Å²	12	77 Å²	77	7%	0.074	43%	0.433	C	S	.	.			trans	-75.6	130	173.8	55.9	0	0	0	0	110.3	N249 P252 V253 P416 P419 L420	T247-N249 PolarHBondContact O-N 3.35Å; T247-P252 WeakPolarHBondContact OG1-CA 3.24Å; T247-V253 PolarHBondContact N-O 3.09Å; T247-V253 PolarHBondContact OG1-N 2.93Å; T247-P416 HydrophobicContact CG2-CB 4.17Å; T247-P416 HydrophobicContact CG2-CG 3.89Å; T247-P419 HydrophobicContact CG2-CG 3.99Å; T247-L420 HydrophobicContact CG2-CD1 3.87Å; T247-L420 HydrophobicContact CG2-CG 4.41Å
248	N	58.3	Low	64.3	Low	166 Å²	166	71.8 Å²	71.8	89%	0.888	42%	0.419	S	S	*	.	S	Bend	trans	-67	23.1	-179.4	-79.6	-14.6	0	0	0	115.9
249	N	60.5	Low	62.9	Low	127 Å²	127	72 Å²	72	68%	0.679	44%	0.437	S	S	*	.	S	Bend	trans	-105.4	166.8	-179	-79.5	-8.4	0	0	0	111.9	T247 N251	T247-N249 PolarHBondContact O-N 3.35Å; N249-N251 PolarHBondContact O-N 2.94Å
250	S	59.8	Low	61.8	Low	116 Å²	116	71 Å²	71	81%	0.811	44%	0.441	S	S	*	.	S	Bend	trans	-58.2	-9.5	176.1	52.8	0	0	0	0	115.5
251	N	69.5	Low	60.5	Low	45 Å²	45	71.8 Å²	71.8	24%	0.241	46%	0.463	C	S	.	.	S	Bend	trans	-128.5	83.4	173.5	-69.8	-69.2	0	0	0	109.8	N249 V253	N249-N251 PolarHBondContact O-N 2.94Å; N251-V253 PolarHBondContact O-N 3.42Å
252	P	78	Confident	59.1	Low	31 Å²	31	71.8 Å²	71.8	20%	0.201	47%	0.474	C	S	.	.			trans	-68.3	133	-176.8	16.6	-20	0	0	0	112.2	T247 P434	T247-P252 WeakPolarHBondContact OG1-CA 3.24Å; P252-P434 HydrophobicContact CB-CG 4.46Å; P252-P434 HydrophobicContact CG-CG 4.1Å; P252-P434 WeakPolarHBondContact O-CD 3.21Å
253	V	84.5	Confident	58.1	Low	4 Å²	4	72.9 Å²	72.9	2%	0.024	47%	0.474	C	S	.	.			trans	-108.1	138	164.3	179.7	0	0	0	0	107.6	S246 T247 N251 L336 F415 P416 L420 N432 F433	S246-V253 WeakPolarHBondContact CA-O 3.44Å; T247-V253 PolarHBondContact N-O 3.09Å; T247-V253 PolarHBondContact OG1-N 2.93Å; N251-V253 PolarHBondContact O-N 3.42Å; V253-L336 HydrophobicContact CG2-CD1 4.13Å; V253-L336 HydrophobicContact CG2-CD2 4.1Å; V253-F415 HydrophobicContact CG1-CD2 4.38Å; V253-F415 HydrophobicContact CG1-CE2 3.82Å; V253-F415 HydrophobicContact CG1-CZ 4.35Å; V253-P416 HydrophobicContact CB-CG 3.89Å; V253-P416 HydrophobicContact CG1-CG 4.19Å; V253-P416 HydrophobicContact CG2-CG 3.96Å; V253-L420 HydrophobicContact CB-CD1 4.24Å; V253-L420 HydrophobicContact CG1-CD1 4.16Å; V253-N432 HydrophobicContact CG1-CB 4.27Å; V253-N432 WeakPolarHBondContact CG1-O 3.37Å; V253-F433 HydrophobicContact CG2-CE1 4.28Å
254	I	85.4	Confident	57.3	Low	22 Å²	22	72.5 Å²	72.5	11%	0.113	47%	0.474	C	S	.	.	B	Isolated β-bridge	trans	-111.6	149.2	-174.9	57.9	167.2	0	0	0	112.2	I244 P256 D431 N432 P434	I244-I254 HydrophobicContact CG2-CB 3.97Å; I244-I254 HydrophobicContact CG2-CG2 4.25Å; I254-P256 HydrophobicContact CD1-CG 4.25Å; I254-P256 HydrophobicContact CG1-CG 4.44Å; I254-P256 WeakPolarHBondContact O-CD 3.4Å; I254-D431 WeakPolarHBondContact CD1-O 3.25Å; I254-N432 VanDerWaalsContact CG1-O 3.25Å; I254-N432 WeakPolarHBondContact CG1-O 3.32Å; I254-N432 PolarHBondContact N-O 3.45Å; I254-N432 PolarHBondContact O-ND2 3.18Å; I254-N432 VanDerWaalsContact O-ND2 3.07Å; I254-P434 HydrophobicContact CG2-CB 4.35Å
255	C	84.6	Confident	55.8	Low	3 Å²	3	75.9 Å²	75.9	2%	0.02	49%	0.493	C	S	.	.			trans	-113.4	91.3	168.3	-176.9	0	0	0	0	110.7	L245 S257 A258 L420 C424	L245-C255 PolarHBondContact O-N 3.3Å; C255-S257 VanDerWaalsContact C-N 3.31Å; C255-S257 PolarHBondContact O-N 3.13Å; C255-A258 PolarHBondContact O-N 3.06Å; C255-L420 HydrophobicContact CB-CD2 3.88Å; C255-C424 HydrophobicContact CB-CB 3.6Å; C255-C424 WeakPolarHBondContact CB-SG 3.44Å; C255-C424 WeakPolarHBondContact SG-CB 3.43Å; C255-C424 CovalentContact SG-SG 2.03Å; C255-C424 PolarHBondContact SG-SG 3.21Å
256	P	75.3	Confident	54.8	Low	52 Å²	52	78.6 Å²	78.6	34%	0.338	51%	0.508	S	S	.	.	G	3₁₀ helix	trans	-61.9	-37.5	-178.9	-20.8	32.4	0	0	0	112.8	I254 A258 G259 E426	I254-P256 HydrophobicContact CD1-CG 4.25Å; I254-P256 HydrophobicContact CG1-CG 4.44Å; I254-P256 WeakPolarHBondContact O-CD 3.4Å; P256-A258 VanDerWaalsContact C-N 3.25Å; P256-A258 PolarHBondContact O-N 2.81Å; P256-G259 PolarHBondContact O-N 2.72Å; P256-E426 HydrophobicContact CG-CG 4.06Å
257	S	61.4	Low	53.4	Low	70 Å²	70	82.1 Å²	82.1	49%	0.49	53%	0.533	S	S	.	.	G	3₁₀ helix	trans	-62.5	-22.8	-176.5	-72.2	0	0	0	0	115.1	C255 G259 E426	C255-S257 VanDerWaalsContact C-N 3.31Å; C255-S257 PolarHBondContact O-N 3.13Å; S257-G259 VanDerWaalsContact C-N 3.31Å; S257-G259 PolarHBondContact O-N 3.02Å; S257-E426 WeakPolarHBondContact CB-OE1 3.49Å; S257-E426 PolarHBondContact N-OE1 3.3Å; S257-E426 PolarHBondContact OG-OE1 2.96Å
258	A	50.7	Low	52	Low	57 Å²	57	86.1 Å²	86.1	47%	0.471	56%	0.561	S	S	.	*	G	3₁₀ helix	trans	-72.8	-21.6	-179.6	0	0	0	0	0	113.5	C255 P256 S260	C255-A258 PolarHBondContact O-N 3.06Å; P256-A258 VanDerWaalsContact C-N 3.25Å; P256-A258 PolarHBondContact O-N 2.81Å; A258-S260 VanDerWaalsContact C-N 3.32Å; A258-S260 PolarHBondContact O-N 3.47Å
259	G	40.9	Very low	50.6	Low	69 Å²	69	85.9 Å²	85.9	71%	0.711	56%	0.557	S	S	*	*	G	3₁₀ helix	trans	-77.7	-10.2	-178.7	0	0	0	0	0	115.1	P256 S257	P256-G259 PolarHBondContact O-N 2.72Å; S257-G259 VanDerWaalsContact C-N 3.31Å; S257-G259 PolarHBondContact O-N 3.02Å
260	S	38.8	Very low	49.3	Very low	118 Å²	118	86.1 Å²	86.1	83%	0.825	56%	0.557	S	S	*	*	G	3₁₀ helix	trans	-94	-5	-175.3	-166.6	0	0	0	0	114.4	A258	A258-S260 VanDerWaalsContact C-N 3.32Å; A258-S260 PolarHBondContact O-N 3.47Å
261	G	28.7	Very low	48.5	Very low	76 Å²	76	87 Å²	87	78%	0.784	55%	0.546	S	S	*	.	S	Bend	trans	-115.2	-3.9	-174.3	0	0	0	0	0	115.7
262	G	26.1	Very low	46.9	Very low	58 Å²	58	95.2 Å²	95.2	60%	0.598	58%	0.575	S	S	*	*	S	Bend	trans	-88.1	131.2	175.7	0	0	0	0	0	111.1
263	H	28.8	Very low	44.9	Very low	169 Å²	169	98.4 Å²	98.4	78%	0.782	60%	0.604	S	S	*	*			trans	-49	149.1	158.7	-123.3	18.2	0	0	0	109.4	D265	H263-D265 PolarHBondContact O-N 2.97Å
264	P	34.5	Very low	43	Very low	117 Å²	117	104.3 Å²	104.3	76%	0.76	64%	0.636	S	S	*	*			trans	-70	84.9	175.3	30.3	-31	0	0	0	107.9	N266	P264-N266 PolarHBondContact O-N 2.92Å; P264-N266 VanDerWaalsContact O-N 3.14Å
265	D	29.5	Very low	41.6	Very low	142 Å²	142	107.3 Å²	107.3	76%	0.759	65%	0.652	S	S	*	*			trans	-69.8	113.5	173.3	-81.3	-17.8	0	0	0	107.8	H263 S267	H263-D265 PolarHBondContact O-N 2.97Å; D265-S267 PolarHBondContact O-N 3.21Å
266	N	36.1	Very low	40.5	Very low	165 Å²	165	112.3 Å²	112.3	88%	0.882	68%	0.682	S	S	*	*			trans	-48.4	96.2	170.4	-80.1	-34	0	0	0	110.2	P264	P264-N266 PolarHBondContact O-N 2.92Å; P264-N266 VanDerWaalsContact O-N 3.14Å
267	S	30.7	Very low	40.1	Very low	105 Å²	105	111.4 Å²	111.4	73%	0.734	68%	0.682	S	S	*	*			trans	-155	111.2	162.1	-80.8	0	0	0	0	111.3	D265	D265-S267 PolarHBondContact O-N 3.21Å
268	S	30.8	Very low	40.5	Very low	97 Å²	97	109.7 Å²	109.7	68%	0.678	67%	0.673	S	S	*	*			trans	54.6	82.5	160.6	59.4	0	0	0	0	117.5	I270	S268-I270 VanDerWaalsContact C-N 3.26Å; S268-I270 PolarHBondContact O-N 3.35Å
269	M	27.7	Very low	41.5	Very low	160 Å²	160	112.3 Å²	112.3	79%	0.788	68%	0.675	S	S	*	*			trans	-60.6	91.3	148.7	-179.7	178.9	-88.8	0	0	108.2	F271	M269-F271 HydrophobicContact CG-CD2 3.92Å; M269-F271 HydrophobicContact CG-CE2 3.7Å; M269-F271 HydrophobicContact CG-CZ 4.34Å; M269-F271 PolarHBondContact O-N 3.44Å; M269-F271 HydrophobicContact SD-CD2 4.21Å; M269-F271 HydrophobicContact SD-CE2 3.38Å; M269-F271 WeakPolarHBondContact SD-CE2 3.28Å; M269-F271 HydrophobicContact SD-CZ 3.61Å
270	I	32.6	Very low	43.1	Very low	132 Å²	132	114.6 Å²	114.6	68%	0.677	67%	0.667	S	S	*	*			trans	-78.9	100.6	171.5	-62.8	-179.4	0	0	0	107.2	S268 Y272	S268-I270 VanDerWaalsContact C-N 3.26Å; S268-I270 PolarHBondContact O-N 3.35Å; I270-Y272 HydrophobicContact CG2-CD2 3.85Å; I270-Y272 HydrophobicContact CG2-CE2 4.18Å; I270-Y272 PolarHBondContact O-N 3.45Å
271	F	43.2	Very low	45	Very low	135 Å²	135	111.1 Å²	111.1	59%	0.592	64%	0.637	S	S	*	*			trans	-68.2	113.9	170.4	-83.9	-92.4	0	0	0	110.7	M269	M269-F271 HydrophobicContact CG-CD2 3.92Å; M269-F271 HydrophobicContact CG-CE2 3.7Å; M269-F271 HydrophobicContact CG-CZ 4.34Å; M269-F271 PolarHBondContact O-N 3.44Å; M269-F271 HydrophobicContact SD-CD2 4.21Å; M269-F271 HydrophobicContact SD-CE2 3.38Å; M269-F271 WeakPolarHBondContact SD-CE2 3.28Å; M269-F271 HydrophobicContact SD-CZ 3.61Å
272	Y	36.1	Very low	47.3	Very low	218 Å²	218	113.9 Å²	113.9	86%	0.855	63%	0.63	S	S	*	*			trans	-146.6	119.8	153.6	-81.3	-71.4	0	0	0	113.5	I270	I270-Y272 HydrophobicContact CG2-CD2 3.85Å; I270-Y272 HydrophobicContact CG2-CE2 4.18Å; I270-Y272 PolarHBondContact O-N 3.45Å
273	A	36.9	Very low	49.8	Very low	97 Å²	97	119 Å²	119	80%	0.802	64%	0.636	S	S	*	*	S	Bend	trans	69.5	112.5	156.1	0	0	0	0	0	120.6
274	N	45.3	Very low	52.3	Low	129 Å²	129	118.2 Å²	118.2	69%	0.69	63%	0.626	S	S	*	*			trans	63.1	58	170.3	-81.8	-1.6	0	0	0	117.5	T276 G277 A278	N274-T276 PolarHBondContact O-N 2.96Å; N274-T276 VanDerWaalsContact O-N 3.12Å; N274-G277 PolarHBondContact O-N 3.46Å; N274-G277 VanDerWaalsContact O-N 3.13Å; N274-A278 PolarHBondContact O-N 2.83Å
275	D	54.8	Low	54.5	Low	85 Å²	85	115.3 Å²	115.3	46%	0.455	60%	0.6	S	S	.	*	H	α-helix	trans	-48.3	-38.4	173.6	-112.8	-38.4	0	0	0	113.9	Q279	D275-Q279 WeakPolarHBondContact O-CB 3.26Å; D275-Q279 WeakPolarHBondContact O-CG 3.45Å; D275-Q279 PolarHBondContact O-N 3.35Å; D275-Q279 PolarHBondContact OD1-NE2 3.42Å
276	T	62.7	Low	57.1	Low	107 Å²	107	111.1 Å²	111.1	66%	0.656	58%	0.578	S	S	*	*	H	α-helix	trans	-68.8	-38.9	-178.1	51.1	0	0	0	0	113	N274 Q280	N274-T276 PolarHBondContact O-N 2.96Å; N274-T276 VanDerWaalsContact O-N 3.12Å; T276-Q280 WeakPolarHBondContact O-CB 3.35Å; T276-Q280 PolarHBondContact O-N 2.73Å
277	G	66.9	Low	59.1	Low	33 Å²	33	107.4 Å²	107.4	34%	0.34	55%	0.554	S	S	.	*	H	α-helix	trans	-74.1	-41.9	-178.1	0	0	0	0	0	112.8	N274 F281	N274-G277 PolarHBondContact O-N 3.46Å; N274-G277 VanDerWaalsContact O-N 3.13Å; G277-F281 WeakPolarHBondContact O-CB 3.24Å; G277-F281 PolarHBondContact O-N 2.89Å
278	A	68.6	Low	61.3	Low	35 Å²	35	104.4 Å²	104.4	29%	0.289	53%	0.533	S	S	.	.	H	α-helix	trans	-69.9	-46.1	177.1	0	0	0	0	0	111.8	N274 Q280 F281 E282	N274-A278 PolarHBondContact O-N 2.83Å; A278-Q280 VanDerWaalsContact C-N 3.29Å; A278-Q280 PolarHBondContact O-N 3.2Å; A278-F281 WeakPolarHBondContact O-CB 3.36Å; A278-F281 PolarHBondContact O-N 2.96Å; A278-F281 VanDerWaalsContact O-N 3.15Å; A278-E282 WeakPolarHBondContact O-CG 3.48Å; A278-E282 PolarHBondContact O-N 2.96Å
279	Q	70.9	Confident	63.7	Low	112 Å²	112	108.8 Å²	108.8	52%	0.523	53%	0.534	S	S	.	.	H	α-helix	trans	-63.8	-35.7	175.7	-68.9	174.4	12.9	0	0	112	D275 K283	D275-Q279 WeakPolarHBondContact O-CB 3.26Å; D275-Q279 WeakPolarHBondContact O-CG 3.45Å; D275-Q279 PolarHBondContact O-N 3.35Å; D275-Q279 PolarHBondContact OD1-NE2 3.42Å; Q279-K283 WeakPolarHBondContact O-CB 3.45Å; Q279-K283 PolarHBondContact O-N 3.43Å
280	Q	75.2	Confident	66.5	Low	116 Å²	116	102.7 Å²	102.7	54%	0.542	51%	0.506	S	S	.	.	H	α-helix	trans	-69	-41.5	173.7	-171.6	168.3	-2.6	0	0	111	T276 A278 K283 W284	T276-Q280 WeakPolarHBondContact O-CB 3.35Å; T276-Q280 PolarHBondContact O-N 2.73Å; A278-Q280 VanDerWaalsContact C-N 3.29Å; A278-Q280 PolarHBondContact O-N 3.2Å; Q280-K283 PolarHBondContact O-N 3.48Å; Q280-W284 PolarHBondContact O-N 3.32Å
281	F	79.1	Confident	69.1	Low	45 Å²	45	96.4 Å²	96.4	20%	0.197	47%	0.474	C	S	.	.	H	α-helix	trans	-59.6	-48	173.7	177.8	-101.7	0	0	0	111.6	F232 G277 A278 K283 W284 W285	F232-F281 HydrophobicContact CB-CD2 4.34Å; F232-F281 HydrophobicContact CB-CE1 4.06Å; F232-F281 HydrophobicContact CB-CE2 3.79Å; F232-F281 HydrophobicContact CB-CZ 3.62Å; F232-F281 AromaticContact CD1-CD1 3.89Å; F232-F281 HydrophobicContact CD1-CD1 3.89Å; F232-F281 AromaticContact CD1-CE1 3.99Å; F232-F281 HydrophobicContact CD1-CE1 3.99Å; F232-F281 HydrophobicContact CD1-CG 4.21Å; F232-F281 HydrophobicContact CD1-CZ 4.39Å; F232-F281 HydrophobicContact CD2-CB 4.23Å; F232-F281 HydrophobicContact CD2-CD1 4.19Å; F232-F281 AromaticContact CD2-CD2 3.49Å; F232-F281 HydrophobicContact CD2-CD2 3.49Å; F232-F281 VanDerWaalsContact CD2-CD2 3.49Å; F232-F281 HydrophobicContact CD2-CE1 4.46Å; F232-F281 AromaticContact CD2-CE2 3.81Å; F232-F281 HydrophobicContact CD2-CE2 3.81Å; F232-F281 AromaticContact CD2-CG 3.69Å; F232-F281 HydrophobicContact CD2-CG 3.69Å; F232-F281 HydrophobicContact CD2-CZ 4.28Å; F232-F281 HydrophobicContact CE1-CB 4.44Å; F232-F281 HydrophobicContact CE1-CD1 4.06Å; F232-F281 HydrophobicContact CE1-CG 4.23Å; F232-F281 HydrophobicContact CE2-CB 3.73Å; F232-F281 HydrophobicContact CE2-CD1 4.34Å; F232-F281 AromaticContact CE2-CD2 3.88Å; F232-F281 HydrophobicContact CE2-CD2 3.88Å; F232-F281 AromaticContact CE2-CG 3.72Å; F232-F281 HydrophobicContact CE2-CG 3.72Å; F232-F281 AromaticContact CG-CD1 3.96Å; F232-F281 HydrophobicContact CG-CD1 3.96Å; F232-F281 AromaticContact CG-CD2 3.9Å; F232-F281 HydrophobicContact CG-CD2 3.9Å; F232-F281 AromaticContact CG-CE1 3.91Å; F232-F281 HydrophobicContact CG-CE1 3.91Å; F232-F281 AromaticContact CG-CE2 3.85Å; F232-F281 HydrophobicContact CG-CE2 3.85Å; F232-F281 AromaticContact CG-CG 3.95Å; F232-F281 HydrophobicContact CG-CG 3.95Å; F232-F281 AromaticContact CG-CZ 3.85Å; F232-F281 HydrophobicContact CG-CZ 3.85Å; F232-F281 HydrophobicContact CZ-CB 3.85Å; F232-F281 HydrophobicContact CZ-CD1 4.29Å; F232-F281 AromaticContact CZ-CG 4Å; F232-F281 HydrophobicContact CZ-CG 4Å; G277-F281 WeakPolarHBondContact O-CB 3.24Å; G277-F281 PolarHBondContact O-N 2.89Å; A278-F281 WeakPolarHBondContact O-CB 3.36Å; A278-F281 PolarHBondContact O-N 2.96Å; A278-F281 VanDerWaalsContact O-N 3.15Å; F281-K283 VanDerWaalsContact C-N 3.28Å; F281-K283 PolarHBondContact O-N 2.91Å; F281-W284 PolarHBondContact O-N 2.95Å; F281-W285 HydrophobicContact CD1-CB 4.44Å; F281-W285 HydrophobicContact CD2-CB 4.02Å; F281-W285 HydrophobicContact CE1-CB 4.15Å; F281-W285 HydrophobicContact CE1-CG 4.34Å; F281-W285 HydrophobicContact CE2-CB 3.7Å; F281-W285 HydrophobicContact CE2-CD2 4.27Å; F281-W285 AromaticContact CE2-CG 3.72Å; F281-W285 HydrophobicContact CE2-CG 3.72Å; F281-W285 HydrophobicContact CG-CB 4.39Å; F281-W285 HydrophobicContact CZ-CB 3.78Å; F281-W285 AromaticContact CZ-CD1 3.49Å; F281-W285 VanDerWaalsContact CZ-CD1 3.49Å; F281-W285 HydrophobicContact CZ-CD2 4.43Å; F281-W285 AromaticContact CZ-CG 3.62Å; F281-W285 HydrophobicContact CZ-CG 3.62Å; F281-W285 WeakPolarHBondContact O-CA 3.23Å; F281-W285 WeakPolarHBondContact O-CB 3.34Å; F281-W285 PolarHBondContact O-N 3.41Å
282	E	77.1	Confident	71.3	Confident	135 Å²	135	90 Å²	90	63%	0.631	45%	0.446	S	S	*	.	H	α-helix	trans	-60.4	-37.6	176.9	-71.8	-174.7	165.9	0	0	112.6	A278	A278-E282 WeakPolarHBondContact O-CG 3.48Å; A278-E282 PolarHBondContact O-N 2.96Å
283	K	79.3	Confident	73.9	Confident	165 Å²	165	85.2 Å²	85.2	72%	0.717	43%	0.43	S	S	*	.	H	α-helix	trans	-67.4	-38	176.8	-173.7	175.1	-178.6	176.8	0	113.1	Q279 Q280 F281	Q279-K283 WeakPolarHBondContact O-CB 3.45Å; Q279-K283 PolarHBondContact O-N 3.43Å; Q280-K283 PolarHBondContact O-N 3.48Å; F281-K283 VanDerWaalsContact C-N 3.28Å; F281-K283 PolarHBondContact O-N 2.91Å
284	W	79.6	Confident	76.4	Confident	153 Å²	153	85.3 Å²	85.3	58%	0.58	41%	0.41	S	S	*	.	H	α-helix	trans	-90.4	-20	-178.3	-75.6	88.8	0	0	0	112.9	Q280 F281 T290 Y294	Q280-W284 PolarHBondContact O-N 3.32Å; F281-W284 PolarHBondContact O-N 2.95Å; W284-T290 VanDerWaalsContact O-CB 3.29Å; W284-T290 WeakPolarHBondContact O-CB 3.34Å; W284-T290 PolarHBondContact O-OG1 3.16Å; W284-Y294 PolarHBondContact O-OH 2.98Å
285	W	82.1	Confident	78.5	Confident	56 Å²	56	79.2 Å²	79.2	21%	0.212	38%	0.377	C	S	.	.	S	Bend	trans	-125.6	60.4	-173.9	-154.5	-95.9	0	0	0	111.3	L224 F225 F281 V291 Y294	L224-W285 HydrophobicContact CD1-CH2 4.5Å; L224-W285 HydrophobicContact CD1-CZ2 4.4Å; L224-W285 HydrophobicContact CG-CH2 4.47Å; L224-W285 HydrophobicContact CG-CZ2 4.22Å; F225-W285 AromaticContact CD2-CD1 3.7Å; F225-W285 VanDerWaalsContact CE2-O 3.26Å; F225-W285 WeakPolarHBondContact CE2-O 3.23Å; F225-W285 PolarHBondContact O-NE1 3.27Å; F225-W285 VanDerWaalsContact O-NE1 3.14Å; F281-W285 HydrophobicContact CD1-CB 4.44Å; F281-W285 HydrophobicContact CD2-CB 4.02Å; F281-W285 HydrophobicContact CE1-CB 4.15Å; F281-W285 HydrophobicContact CE1-CG 4.34Å; F281-W285 HydrophobicContact CE2-CB 3.7Å; F281-W285 HydrophobicContact CE2-CD2 4.27Å; F281-W285 AromaticContact CE2-CG 3.72Å; F281-W285 HydrophobicContact CE2-CG 3.72Å; F281-W285 HydrophobicContact CG-CB 4.39Å; F281-W285 HydrophobicContact CZ-CB 3.78Å; F281-W285 AromaticContact CZ-CD1 3.49Å; F281-W285 VanDerWaalsContact CZ-CD1 3.49Å; F281-W285 HydrophobicContact CZ-CD2 4.43Å; F281-W285 AromaticContact CZ-CG 3.62Å; F281-W285 HydrophobicContact CZ-CG 3.62Å; F281-W285 WeakPolarHBondContact O-CA 3.23Å; F281-W285 WeakPolarHBondContact O-CB 3.34Å; F281-W285 PolarHBondContact O-N 3.41Å; W285-V291 HydrophobicContact CD2-CG2 4.22Å; W285-V291 HydrophobicContact CG-CG2 4.36Å; W285-Y294 HydrophobicContact CE3-CD2 4.37Å; W285-Y294 AromaticContact CE3-CE2 3.97Å; W285-Y294 HydrophobicContact CE3-CE2 3.97Å; W285-Y294 AromaticContact CZ3-CD2 3.97Å; W285-Y294 HydrophobicContact CZ3-CD2 3.97Å; W285-Y294 AromaticContact CZ3-CE2 3.92Å; W285-Y294 HydrophobicContact CZ3-CE2 3.92Å
286	D	83.3	Confident	80.2	Confident	54 Å²	54	76.8 Å²	76.8	29%	0.289	37%	0.366	S	S	.	.			trans	-94.2	132	178	-174.9	-78.4	0	0	0	111	S288 R289 T290 V291	D286-S288 VanDerWaalsContact C-N 3.25Å; D286-S288 PolarHBondContact O-N 3.47Å; D286-S288 WeakPolarHBondContact OD1-CA 3.47Å; D286-S288 PolarHBondContact OD1-N 2.72Å; D286-S288 PolarHBondContact OD1-OG 3.24Å; D286-R289 HydrophobicContact CB-CB 4.09Å; D286-R289 PolarHBondContact OD1-N 2.93Å; D286-T290 PolarHBondContact N-OG1 3.41Å; D286-T290 PolarHBondContact O-N 3.37Å; D286-T290 PolarHBondContact O-OG1 2.75Å; D286-V291 WeakPolarHBondContact O-CG2 3.48Å; D286-V291 PolarHBondContact O-N 2.84Å
287	K	78	Confident	81.4	Confident	87 Å²	87	74.6 Å²	74.6	38%	0.378	36%	0.364	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55.7	-37.7	-178.8	-178.6	175	175	170.8	0	113	N222 F225	N222-K287 VanDerWaalsContact OD1-CE 3.29Å; N222-K287 WeakPolarHBondContact OD1-CE 3.29Å; N222-K287 PolarHBondContact OD1-NZ 2.99Å; N222-K287 VanDerWaalsContact OD1-NZ 3.1Å; F225-K287 HydrophobicContact CB-CB 4.41Å; F225-K287 HydrophobicContact CB-CG 4.42Å; F225-K287 HydrophobicContact CD1-CB 3.95Å; F225-K287 HydrophobicContact CD1-CD 4.09Å; F225-K287 HydrophobicContact CD1-CG 4.1Å; F225-K287 HydrophobicContact CD2-CB 3.8Å; F225-K287 HydrophobicContact CE1-CB 4.14Å; F225-K287 HydrophobicContact CE1-CD 4.33Å; F225-K287 HydrophobicContact CE2-CB 4Å; F225-K287 HydrophobicContact CG-CB 3.77Å; F225-K287 HydrophobicContact CG-CG 4.13Å; F225-K287 HydrophobicContact CZ-CB 4.16Å
288	S	78.1	Confident	82.4	Confident	42 Å²	42	77 Å²	77	29%	0.294	37%	0.369	S	S	.	.	T	Hydrogen-bonded Turn	trans	-101.8	-23.1	-172.1	66.7	0	0	0	0	113.6	D286 C497	D286-S288 VanDerWaalsContact C-N 3.25Å; D286-S288 PolarHBondContact O-N 3.47Å; D286-S288 WeakPolarHBondContact OD1-CA 3.47Å; D286-S288 PolarHBondContact OD1-N 2.72Å; D286-S288 PolarHBondContact OD1-OG 3.24Å; S288-C497 VanDerWaalsContact O-CA 3.31Å; S288-C497 WeakPolarHBondContact O-CA 3.45Å; S288-C497 WeakPolarHBondContact O-CB 3.31Å; S288-C497 PolarHBondContact O-SG 3.5Å
289	R	80.3	Confident	83.3	Confident	188 Å²	188	75.3 Å²	75.3	71%	0.709	36%	0.355	S	S	*	.	T	Hydrogen-bonded Turn	trans	-109.1	-46.6	-172	-66.1	-176.6	179.6	-173.6	1.4	115.2	D286 F293	D286-R289 HydrophobicContact CB-CB 4.09Å; D286-R289 PolarHBondContact OD1-N 2.93Å; R289-F293 WeakPolarHBondContact O-CD2 3.31Å; R289-F293 WeakPolarHBondContact O-CE2 3.3Å
290	T	85.5	Confident	84.2	Confident	32 Å²	32	71.8 Å²	71.8	20%	0.196	34%	0.339	C	S	.	.	T	Hydrogen-bonded Turn	trans	-105.3	-42	-170.2	59.9	0	0	0	0	112.7	W284 D286 F293 Y294	W284-T290 VanDerWaalsContact O-CB 3.29Å; W284-T290 WeakPolarHBondContact O-CB 3.34Å; W284-T290 PolarHBondContact O-OG1 3.16Å; D286-T290 PolarHBondContact N-OG1 3.41Å; D286-T290 PolarHBondContact O-N 3.37Å; D286-T290 PolarHBondContact O-OG1 2.75Å; T290-F293 PolarHBondContact O-N 2.96Å; T290-Y294 PolarHBondContact O-N 3.43Å
291	V	87.8	Confident	84.8	Confident	0 Å²	0	69.8 Å²	69.8	0%	0	34%	0.336	C	S	.	.	H	α-helix	trans	-58.2	-43	-176.2	176.8	0	0	0	0	113.3	S221 L224 F225 W285 D286 F293 Y294 L295	S221-V291 WeakPolarHBondContact O-CG1 3.27Å; L224-V291 HydrophobicContact CB-CG1 3.93Å; L224-V291 HydrophobicContact CD2-CG1 3.85Å; L224-V291 HydrophobicContact CG-CG1 3.94Å; F225-V291 HydrophobicContact CB-CG1 4.29Å; F225-V291 HydrophobicContact CB-CG2 4.21Å; F225-V291 HydrophobicContact CD2-CG2 4.24Å; W285-V291 HydrophobicContact CD2-CG2 4.22Å; W285-V291 HydrophobicContact CG-CG2 4.36Å; D286-V291 WeakPolarHBondContact O-CG2 3.48Å; D286-V291 PolarHBondContact O-N 2.84Å; V291-F293 PolarHBondContact O-N 3.34Å; V291-Y294 PolarHBondContact O-N 3.2Å; V291-L295 PolarHBondContact O-N 2.99Å
292	P	89.4	Confident	85.1	Confident	0 Å²	0	69.5 Å²	69.5	0%	0	34%	0.337	C	S	.	.	H	α-helix	trans	-60.1	-29	176.6	-24.9	35.1	0	0	0	113.9	W217 V493 A496	W217-P292 WeakPolarHBondContact CZ2-O 3.47Å; W217-P292 PolarHBondContact NE1-O 3.34Å; P292-V493 HydrophobicContact CB-CG1 4.49Å; P292-A496 HydrophobicContact CB-CB 4.09Å; P292-A496 HydrophobicContact CG-CB 3.97Å
293	F	90.7	Very high	85.5	Confident	119 Å²	119	63.6 Å²	63.6	52%	0.522	31%	0.309	S	S	.	.	H	α-helix	trans	-78.9	-31.9	178.8	-69.5	-89.1	0	0	0	112.7	R289 T290 V291 L295 V296 V493	R289-F293 WeakPolarHBondContact O-CD2 3.31Å; R289-F293 WeakPolarHBondContact O-CE2 3.3Å; T290-F293 PolarHBondContact O-N 2.96Å; V291-F293 PolarHBondContact O-N 3.34Å; F293-L295 PolarHBondContact O-N 3.26Å; F293-V296 VanDerWaalsContact O-CB 3.25Å; F293-V296 WeakPolarHBondContact O-CB 3.4Å; F293-V296 PolarHBondContact O-N 2.84Å; F293-V493 HydrophobicContact CD1-CG1 4.27Å; F293-V493 HydrophobicContact CD2-CG1 4.45Å; F293-V493 HydrophobicContact CE1-CG1 3.82Å; F293-V493 HydrophobicContact CE2-CG1 4.04Å; F293-V493 HydrophobicContact CZ-CG1 3.7Å
294	Y	90.3	Very high	85.7	Confident	98 Å²	98	57.7 Å²	57.7	38%	0.384	29%	0.286	S	S	.	.	H	α-helix	trans	-62.6	-34.1	174.4	-63.2	-33.7	0	0	0	112.3	W284 W285 T290 V291 V296 G297	W284-Y294 PolarHBondContact O-OH 2.98Å; W285-Y294 HydrophobicContact CE3-CD2 4.37Å; W285-Y294 AromaticContact CE3-CE2 3.97Å; W285-Y294 HydrophobicContact CE3-CE2 3.97Å; W285-Y294 AromaticContact CZ3-CD2 3.97Å; W285-Y294 HydrophobicContact CZ3-CD2 3.97Å; W285-Y294 AromaticContact CZ3-CE2 3.92Å; W285-Y294 HydrophobicContact CZ3-CE2 3.92Å; T290-Y294 PolarHBondContact O-N 3.43Å; V291-Y294 PolarHBondContact O-N 3.2Å; Y294-V296 PolarHBondContact O-N 3.06Å; Y294-G297 PolarHBondContact O-N 2.95Å
295	L	89	Confident	85.7	Confident	1 Å²	1	55.9 Å²	55.9	1%	0.005	28%	0.282	C	S	.	.	H	α-helix	trans	-63.5	-27.2	173.1	-69.9	174.4	0	0	0	113	W217 M220 S221 L224 V291 F293 L298 L299	W217-L295 HydrophobicContact CH2-CB 4Å; W217-L295 HydrophobicContact CZ2-CB 3.65Å; M220-L295 HydrophobicContact CB-CD1 3.78Å; M220-L295 HydrophobicContact CB-CD2 4.49Å; S221-L295 WeakPolarHBondContact OG-CD1 3.37Å; L224-L295 HydrophobicContact CD2-CD2 3.68Å; L224-L295 HydrophobicContact CD2-CG 3.9Å; V291-L295 PolarHBondContact O-N 2.99Å; F293-L295 PolarHBondContact O-N 3.26Å; L295-L298 PolarHBondContact O-N 2.87Å; L295-L299 HydrophobicContact CB-CD1 4.28Å; L295-L299 HydrophobicContact CD2-CD1 4.5Å; L295-L299 WeakPolarHBondContact O-CB 3.21Å; L295-L299 WeakPolarHBondContact O-CG 3.25Å; L295-L299 PolarHBondContact O-N 2.95Å
296	V	90.6	Very high	85.3	Confident	35 Å²	35	60.2 Å²	60.2	21%	0.212	30%	0.302	C	S	.	.	H	α-helix	trans	-62.2	-47.2	176	-178.2	0	0	0	0	110.7	W217 F293 Y294 L298 L300 V489 V493	W217-V296 HydrophobicContact CH2-CG2 4.08Å; W217-V296 HydrophobicContact CZ2-CB 4.49Å; W217-V296 HydrophobicContact CZ2-CG2 3.63Å; F293-V296 VanDerWaalsContact O-CB 3.25Å; F293-V296 WeakPolarHBondContact O-CB 3.4Å; F293-V296 PolarHBondContact O-N 2.84Å; Y294-V296 PolarHBondContact O-N 3.06Å; V296-L298 PolarHBondContact O-N 3.31Å; V296-L300 HydrophobicContact CG1-CB 4.16Å; V296-L300 HydrophobicContact CG1-CD2 4.16Å; V296-L300 WeakPolarHBondContact O-CB 3.41Å; V296-L300 PolarHBondContact O-N 2.92Å; V296-V489 HydrophobicContact CG1-CG1 4.23Å; V296-V489 HydrophobicContact CG2-CG1 3.85Å; V296-V493 HydrophobicContact CG2-CG2 3.76Å
297	G	87.9	Confident	84.7	Confident	60 Å²	60	60.8 Å²	60.8	62%	0.619	31%	0.311	S	S	*	.	H	α-helix	trans	-60.2	-29.3	179.3	0	0	0	0	0	113.2	Y294 P301	Y294-G297 PolarHBondContact O-N 2.95Å; G297-P301 WeakPolarHBondContact O-CD 3.45Å; G297-P301 WeakPolarHBondContact O-CG 3.44Å
298	L	87.1	Confident	84.3	Confident	84 Å²	84	58 Å²	58	44%	0.44	30%	0.302	S	S	.	.	H	α-helix	trans	-88.3	-46.9	-179	-171.3	65.3	0	0	0	113	L295 V296 L302 M452	L295-L298 PolarHBondContact O-N 2.87Å; V296-L298 PolarHBondContact O-N 3.31Å; L298-L302 WeakPolarHBondContact O-CD1 3.19Å; L298-L302 WeakPolarHBondContact O-CG 3.25Å; L298-M452 HydrophobicContact CD1-CE 4.18Å; L298-M452 HydrophobicContact CD2-CE 3.25Å; L298-M452 HydrophobicContact CD2-SD 3.73Å; L298-M452 HydrophobicContact CG-CE 3.69Å
299	L	88.5	Confident	83.9	Confident	0 Å²	0	59.3 Å²	59.3	0%	0	31%	0.31	C	S	.	.	H	α-helix	trans	-90.7	-30.3	-170	-65.6	176.4	0	0	0	113.8	W217 M220 L295 L302 L303 M452 Y455	W217-L299 HydrophobicContact CE3-CD1 3.97Å; W217-L299 HydrophobicContact CH2-CB 4.15Å; W217-L299 HydrophobicContact CH2-CD1 3.96Å; W217-L299 HydrophobicContact CZ3-CB 3.96Å; W217-L299 HydrophobicContact CZ3-CD1 3.45Å; W217-L299 VanDerWaalsContact CZ3-CD1 3.45Å; W217-L299 HydrophobicContact CZ3-CG 4.33Å; M220-L299 HydrophobicContact CE-CD1 3.42Å; M220-L299 VanDerWaalsContact CE-CD1 3.42Å; M220-L299 HydrophobicContact SD-CD1 3.87Å; L295-L299 HydrophobicContact CB-CD1 4.28Å; L295-L299 HydrophobicContact CD2-CD1 4.5Å; L295-L299 WeakPolarHBondContact O-CB 3.21Å; L295-L299 WeakPolarHBondContact O-CG 3.25Å; L295-L299 PolarHBondContact O-N 2.95Å; L299-L302 HydrophobicContact CD2-CD1 4.14Å; L299-L302 PolarHBondContact O-N 3.45Å; L299-L303 PolarHBondContact O-N 2.97Å; L299-M452 HydrophobicContact CD2-CB 4.27Å; L299-M452 HydrophobicContact CD2-CG 4.11Å; L299-Y455 HydrophobicContact CB-CD1 4.38Å; L299-Y455 HydrophobicContact CB-CE1 4.39Å; L299-Y455 HydrophobicContact CD1-CD1 4.09Å; L299-Y455 HydrophobicContact CD1-CE1 4.3Å; L299-Y455 HydrophobicContact CD2-CD1 4.47Å
300	L	88.7	Confident	83.5	Confident	38 Å²	38	56 Å²	56	20%	0.199	30%	0.301	C	S	.	.	H	α-helix	trans	-62.2	-42.9	179.7	-172.3	70.4	0	0	0	111.9	V296 L302 L303 N304 N485 V489	V296-L300 HydrophobicContact CG1-CB 4.16Å; V296-L300 HydrophobicContact CG1-CD2 4.16Å; V296-L300 WeakPolarHBondContact O-CB 3.41Å; V296-L300 PolarHBondContact O-N 2.92Å; L300-L302 VanDerWaalsContact C-N 3.32Å; L300-L302 PolarHBondContact O-N 3.32Å; L300-L303 PolarHBondContact O-N 2.9Å; L300-N304 PolarHBondContact O-ND2 3.33Å; L300-N485 HydrophobicContact CD1-CB 4.32Å; L300-V489 HydrophobicContact CD1-CG2 4.15Å
301	P	87.9	Confident	82.8	Confident	73 Å²	73	55.1 Å²	55.1	47%	0.474	30%	0.295	S	S	.	.	H	α-helix	trans	-60.7	-41	173	-23.8	35.2	0	0	0	112.5	G297 L303 N304	G297-P301 WeakPolarHBondContact O-CD 3.45Å; G297-P301 WeakPolarHBondContact O-CG 3.44Å; P301-L303 VanDerWaalsContact C-N 3.34Å; P301-L303 PolarHBondContact O-N 3.43Å; P301-N304 PolarHBondContact O-N 3.29Å
302	L	86.3	Confident	81.9	Confident	40 Å²	40	58.1 Å²	58.1	21%	0.209	32%	0.316	C	S	.	.	H	α-helix	trans	-65.3	-35.4	-178.3	-63.2	172.3	0	0	0	112.5	L298 L299 L300 N304 F305 F311 P456	L298-L302 WeakPolarHBondContact O-CD1 3.19Å; L298-L302 WeakPolarHBondContact O-CG 3.25Å; L299-L302 HydrophobicContact CD2-CD1 4.14Å; L299-L302 PolarHBondContact O-N 3.45Å; L300-L302 VanDerWaalsContact C-N 3.32Å; L300-L302 PolarHBondContact O-N 3.32Å; L302-N304 PolarHBondContact O-N 3.18Å; L302-F305 HydrophobicContact CD2-CE2 3.95Å; L302-F305 PolarHBondContact O-N 3.23Å; L302-F311 HydrophobicContact CB-CZ 3.94Å; L302-F311 HydrophobicContact CD2-CE1 4.17Å; L302-F311 HydrophobicContact CD2-CZ 3.79Å; L302-F311 HydrophobicContact CG-CZ 4.35Å; L302-P456 HydrophobicContact CB-CG 3.97Å
303	L	84.5	Confident	81.1	Confident	11 Å²	11	65.6 Å²	65.6	6%	0.058	35%	0.348	C	S	.	.	H	α-helix	trans	-67.2	-21.6	176.1	-79.9	170.6	0	0	0	114	M213 L299 L300 P301 F305 Y455 N485 V489	M213-L303 HydrophobicContact CE-CD2 4.09Å; L299-L303 PolarHBondContact O-N 2.97Å; L300-L303 PolarHBondContact O-N 2.9Å; P301-L303 VanDerWaalsContact C-N 3.34Å; P301-L303 PolarHBondContact O-N 3.43Å; L303-F305 VanDerWaalsContact C-N 3.34Å; L303-Y455 HydrophobicContact CD1-CD1 4.33Å; L303-Y455 HydrophobicContact CD1-CE1 3.6Å; L303-Y455 HydrophobicContact CD2-CD1 4.22Å; L303-Y455 HydrophobicContact CD2-CE1 4.13Å; L303-Y455 HydrophobicContact CG-CD1 4.31Å; L303-Y455 HydrophobicContact CG-CE1 4.07Å; L303-N485 PolarHBondContact O-ND2 3Å; L303-V489 HydrophobicContact CD1-CG2 3.51Å
304	N	84.1	Confident	80.4	Confident	41 Å²	41	63.1 Å²	63.1	22%	0.219	34%	0.337	C	S	.	.	T	Hydrogen-bonded Turn	trans	-87.5	-2.8	-177.2	-75.8	-68.5	0	0	0	113.4	L300 P301 L302 N485	L300-N304 PolarHBondContact O-ND2 3.33Å; P301-N304 PolarHBondContact O-N 3.29Å; L302-N304 PolarHBondContact O-N 3.18Å; N304-N485 PolarHBondContact OD1-ND2 3.39Å
305	F	80.3	Confident	79.5	Confident	114 Å²	114	61 Å²	61	50%	0.5	33%	0.332	S	S	.	.			trans	-64.9	137.1	175.2	-72.2	-27.7	0	0	0	112.4	L302 L303 S307 F311	L302-F305 HydrophobicContact CD2-CE2 3.95Å; L302-F305 PolarHBondContact O-N 3.23Å; L303-F305 VanDerWaalsContact C-N 3.34Å; F305-S307 PolarHBondContact O-N 3.01Å; F305-F311 AromaticContact CD2-CE2 3.82Å; F305-F311 HydrophobicContact CD2-CE2 3.82Å; F305-F311 AromaticContact CD2-CZ 3.9Å; F305-F311 HydrophobicContact CD2-CZ 3.9Å; F305-F311 HydrophobicContact CE2-CZ 4.28Å
306	K	72.5	Confident	79	Confident	148 Å²	148	67.2 Å²	67.2	64%	0.643	36%	0.364	S	S	*	.	S	Bend	trans	-69.9	-32.2	-173.6	-168.9	174.5	-179.3	178.7	0	112.6
307	S	70.6	Confident	78.4	Confident	66 Å²	66	67.7 Å²	67.7	46%	0.462	37%	0.365	S	S	.	.			trans	-122.2	134.5	-176.9	58.1	0	0	0	0	112.3	F305 S309	F305-S307 PolarHBondContact O-N 3.01Å; S307-S309 VanDerWaalsContact C-N 3.28Å; S307-S309 PolarHBondContact O-N 3.15Å
308	P	69.8	Low	78.1	Confident	29 Å²	29	64.9 Å²	64.9	19%	0.188	34%	0.337	C	S	.	.	S	Bend	trans	-83.4	-2.5	177.4	35.1	-37.6	0	0	0	113.1	F310 F311 S312 L457 Y460	P308-F310 PolarHBondContact O-N 3.22Å; P308-F311 PolarHBondContact O-N 3.11Å; P308-S312 PolarHBondContact O-N 3Å; P308-L457 HydrophobicContact CB-CD1 3.82Å; P308-Y460 HydrophobicContact CB-CD1 4.21Å; P308-Y460 HydrophobicContact CB-CG 4.15Å; P308-Y460 HydrophobicContact CG-CD1 3.75Å; P308-Y460 HydrophobicContact CG-CD2 4.29Å; P308-Y460 HydrophobicContact CG-CE1 3.79Å; P308-Y460 HydrophobicContact CG-CE2 4.32Å; P308-Y460 HydrophobicContact CG-CG 4.02Å
309	S	70	Confident	78	Confident	68 Å²	68	62.6 Å²	62.6	48%	0.476	33%	0.326	S	S	.	.	H	α-helix	trans	-60.9	-30.9	-171.2	54.8	0	0	0	0	113.1	S307 S312	S307-S309 VanDerWaalsContact C-N 3.28Å; S307-S309 PolarHBondContact O-N 3.15Å; S309-S312 PolarHBondContact O-OG 3.45Å
310	F	73.1	Confident	78	Confident	118 Å²	118	65.8 Å²	65.8	52%	0.518	35%	0.345	S	S	.	.	H	α-helix	trans	-62.9	-50.5	172.8	-179.6	-103.4	0	0	0	111.8	P308 S312 K313 F314	P308-F310 PolarHBondContact O-N 3.22Å; F310-S312 VanDerWaalsContact C-N 3.34Å; F310-S312 PolarHBondContact O-N 2.87Å; F310-K313 PolarHBondContact O-N 3.02Å; F310-F314 HydrophobicContact CD1-CE2 4.02Å; F310-F314 HydrophobicContact CD2-CE2 4.39Å; F310-F314 HydrophobicContact CE1-CD2 4.36Å; F310-F314 AromaticContact CE1-CE2 3.53Å; F310-F314 HydrophobicContact CE1-CE2 3.53Å; F310-F314 HydrophobicContact CE1-CZ 4.24Å; F310-F314 AromaticContact CE2-CE2 3.94Å; F310-F314 HydrophobicContact CE2-CE2 3.94Å; F310-F314 HydrophobicContact CE2-CZ 4.41Å; F310-F314 HydrophobicContact CG-CE2 4.43Å; F310-F314 AromaticContact CZ-CE2 3.49Å; F310-F314 HydrophobicContact CZ-CE2 3.49Å; F310-F314 VanDerWaalsContact CZ-CE2 3.49Å; F310-F314 AromaticContact CZ-CZ 3.88Å; F310-F314 HydrophobicContact CZ-CZ 3.88Å; F310-F314 WeakPolarHBondContact O-CD2 3.4Å
311	F	70.6	Confident	78	Confident	15 Å²	15	64 Å²	64	7%	0.066	34%	0.337	C	S	.	.	H	α-helix	trans	-68.4	-31.4	-178.4	-63.7	-68.1	0	0	0	113.2	L302 F305 P308 K313 F314 P456	L302-F311 HydrophobicContact CB-CZ 3.94Å; L302-F311 HydrophobicContact CD2-CE1 4.17Å; L302-F311 HydrophobicContact CD2-CZ 3.79Å; L302-F311 HydrophobicContact CG-CZ 4.35Å; F305-F311 AromaticContact CD2-CE2 3.82Å; F305-F311 HydrophobicContact CD2-CE2 3.82Å; F305-F311 AromaticContact CD2-CZ 3.9Å; F305-F311 HydrophobicContact CD2-CZ 3.9Å; F305-F311 HydrophobicContact CE2-CZ 4.28Å; P308-F311 PolarHBondContact O-N 3.11Å; F311-K313 PolarHBondContact O-N 3.11Å; F311-K313 VanDerWaalsContact O-N 3.16Å; F311-F314 WeakPolarHBondContact O-CB 3.21Å; F311-F314 PolarHBondContact O-N 3.37Å; F311-P456 HydrophobicContact CD1-CG 4.42Å; F311-P456 HydrophobicContact CD2-CB 3.85Å; F311-P456 HydrophobicContact CD2-CG 4.46Å; F311-P456 HydrophobicContact CE1-CG 4.12Å; F311-P456 HydrophobicContact CE2-CB 3.71Å; F311-P456 HydrophobicContact CE2-CG 4.15Å; F311-P456 HydrophobicContact CG-CB 4.3Å; F311-P456 HydrophobicContact CZ-CB 4.08Å; F311-P456 HydrophobicContact CZ-CG 3.98Å
312	S	67.9	Low	78.1	Confident	62 Å²	62	60.8 Å²	60.8	43%	0.434	32%	0.315	S	S	.	.	H	α-helix	trans	-58.8	-28.9	177.5	72.9	0	0	0	0	113.6	P308 S309 F310 F314 N315	P308-S312 PolarHBondContact O-N 3Å; S309-S312 PolarHBondContact O-OG 3.45Å; F310-S312 VanDerWaalsContact C-N 3.34Å; F310-S312 PolarHBondContact O-N 2.87Å; S312-F314 VanDerWaalsContact C-N 3.31Å; S312-F314 PolarHBondContact O-N 2.89Å; S312-N315 VanDerWaalsContact O-CB 3.27Å; S312-N315 WeakPolarHBondContact O-CB 3.07Å; S312-N315 PolarHBondContact O-N 3.29Å
313	K	73.1	Confident	78.4	Confident	157 Å²	157	63.7 Å²	63.7	68%	0.683	33%	0.33	S	S	*	.	H	α-helix	trans	-70.3	-28.3	176.7	-63.9	179.8	-178.5	-179.3	0	112.5	F310 F311 N315	F310-K313 PolarHBondContact O-N 3.02Å; F311-K313 PolarHBondContact O-N 3.11Å; F311-K313 VanDerWaalsContact O-N 3.16Å; K313-N315 PolarHBondContact O-N 2.95Å
314	F	75.1	Confident	78.8	Confident	68 Å²	68	65 Å²	65	30%	0.298	34%	0.335	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79.1	-3.4	177.8	-67.9	-82.8	0	0	0	113	F310 F311 S312 I316 L317 T453	F310-F314 HydrophobicContact CD1-CE2 4.02Å; F310-F314 HydrophobicContact CD2-CE2 4.39Å; F310-F314 HydrophobicContact CE1-CD2 4.36Å; F310-F314 AromaticContact CE1-CE2 3.53Å; F310-F314 HydrophobicContact CE1-CE2 3.53Å; F310-F314 HydrophobicContact CE1-CZ 4.24Å; F310-F314 AromaticContact CE2-CE2 3.94Å; F310-F314 HydrophobicContact CE2-CE2 3.94Å; F310-F314 HydrophobicContact CE2-CZ 4.41Å; F310-F314 HydrophobicContact CG-CE2 4.43Å; F310-F314 AromaticContact CZ-CE2 3.49Å; F310-F314 HydrophobicContact CZ-CE2 3.49Å; F310-F314 VanDerWaalsContact CZ-CE2 3.49Å; F310-F314 AromaticContact CZ-CZ 3.88Å; F310-F314 HydrophobicContact CZ-CZ 3.88Å; F310-F314 WeakPolarHBondContact O-CD2 3.4Å; F311-F314 WeakPolarHBondContact O-CB 3.21Å; F311-F314 PolarHBondContact O-N 3.37Å; S312-F314 VanDerWaalsContact C-N 3.31Å; S312-F314 PolarHBondContact O-N 2.89Å; F314-I316 PolarHBondContact O-N 3.36Å; F314-I316 VanDerWaalsContact O-N 3.16Å; F314-L317 WeakPolarHBondContact O-CB 3.44Å; F314-L317 PolarHBondContact O-N 3.21Å; F314-T453 HydrophobicContact CB-CG2 3.8Å; F314-T453 HydrophobicContact CG-CG2 4.15Å
315	N	72.9	Confident	79.3	Confident	52 Å²	52	63.1 Å²	63.1	28%	0.278	33%	0.325	S	S	.	.	H	α-helix	trans	-62	-25.1	178.1	-159.7	20.6	0	0	0	113.1	N128 S312 K313 L317 G318	N128-N315 PolarHBondContact ND2-O 3.49Å; N128-N315 VanDerWaalsContact ND2-O 3.14Å; N128-N315 PolarHBondContact ND2-OD1 2.98Å; S312-N315 VanDerWaalsContact O-CB 3.27Å; S312-N315 WeakPolarHBondContact O-CB 3.07Å; S312-N315 PolarHBondContact O-N 3.29Å; K313-N315 PolarHBondContact O-N 2.95Å; N315-L317 PolarHBondContact O-N 2.94Å; N315-G318 PolarHBondContact O-N 3.26Å; N315-G318 VanDerWaalsContact O-N 3.1Å
316	I	78.6	Confident	79.9	Confident	132 Å²	132	59.5 Å²	59.5	68%	0.677	31%	0.31	S	S	*	.	H	α-helix	trans	-55.4	-32.9	171.9	-64.2	171.4	0	0	0	111	F314 G318 T319 V320	F314-I316 PolarHBondContact O-N 3.36Å; F314-I316 VanDerWaalsContact O-N 3.16Å; I316-G318 VanDerWaalsContact C-N 3.34Å; I316-T319 WeakPolarHBondContact O-CB 3.39Å; I316-T319 PolarHBondContact O-N 2.92Å; I316-V320 PolarHBondContact O-N 3.07Å
317	L	76.8	Confident	81	Confident	45 Å²	45	57.9 Å²	57.9	24%	0.236	30%	0.303	C	S	.	.	H	α-helix	trans	-74.1	-27.2	-177.9	-165.1	57.7	0	0	0	113.3	F314 N315 T319 V320 S321 F449	F314-L317 WeakPolarHBondContact O-CB 3.44Å; F314-L317 PolarHBondContact O-N 3.21Å; N315-L317 PolarHBondContact O-N 2.94Å; L317-T319 PolarHBondContact O-N 3.44Å; L317-V320 HydrophobicContact CD1-CB 4.22Å; L317-V320 HydrophobicContact CD1-CG2 4.5Å; L317-V320 PolarHBondContact O-N 2.9Å; L317-S321 WeakPolarHBondContact O-CB 3.48Å; L317-S321 PolarHBondContact O-N 3.36Å; L317-F449 HydrophobicContact CD2-CD1 3.02Å; L317-F449 HydrophobicContact CD2-CE1 3.03Å; L317-F449 HydrophobicContact CD2-CG 4.26Å; L317-F449 HydrophobicContact CD2-CZ 4.29Å; L317-F449 HydrophobicContact CG-CD1 4.24Å; L317-F449 HydrophobicContact CG-CE1 4.49Å
318	G	82.1	Confident	82.1	Confident	1 Å²	1	54.7 Å²	54.7	1%	0.01	28%	0.281	C	S	.	.	H	α-helix	trans	-59.9	-39.4	169.7	0	0	0	0	0	111.6	N315 I316 V320 S321 V322 Q450	N315-G318 PolarHBondContact O-N 3.26Å; N315-G318 VanDerWaalsContact O-N 3.1Å; I316-G318 VanDerWaalsContact C-N 3.34Å; G318-V320 PolarHBondContact O-N 2.85Å; G318-S321 WeakPolarHBondContact O-CB 3.32Å; G318-S321 PolarHBondContact O-N 3.19Å; G318-V322 WeakPolarHBondContact O-CG2 3.47Å; G318-V322 PolarHBondContact O-N 2.81Å; G318-Q450 VanDerWaalsContact CA-CD 3.48Å
319	T	83.9	Confident	83.3	Confident	37 Å²	37	53.5 Å²	53.5	23%	0.227	27%	0.273	C	S	.	.	H	α-helix	trans	-64.2	-41.7	175.4	-56.2	0	0	0	0	111.9	W127 N128 I316 L317 S321 V322 L323	W127-T319 HydrophobicContact CZ3-CG2 4.16Å; N128-T319 VanDerWaalsContact CG-OG1 3.28Å; N128-T319 WeakPolarHBondContact OD1-CA 3.34Å; N128-T319 PolarHBondContact OD1-N 3.48Å; N128-T319 VanDerWaalsContact OD1-N 3.15Å; N128-T319 PolarHBondContact OD1-OG1 3.32Å; I316-T319 WeakPolarHBondContact O-CB 3.39Å; I316-T319 PolarHBondContact O-N 2.92Å; L317-T319 PolarHBondContact O-N 3.44Å; T319-S321 VanDerWaalsContact C-N 3.34Å; T319-S321 PolarHBondContact O-N 3.29Å; T319-V322 PolarHBondContact O-N 3.06Å; T319-L323 HydrophobicContact CG2-CD1 4.13Å; T319-L323 HydrophobicContact CG2-CG 4.47Å; T319-L323 WeakPolarHBondContact O-CB 3.49Å; T319-L323 VanDerWaalsContact O-CG 3.29Å; T319-L323 WeakPolarHBondContact O-CG 3.2Å; T319-L323 PolarHBondContact O-N 3.21Å
320	V	88.9	Confident	84.5	Confident	66 Å²	66	52.4 Å²	52.4	40%	0.4	26%	0.264	S	S	.	.	H	α-helix	trans	-62	-43.5	176	177.6	0	0	0	0	111.2	I316 L317 G318 L323 Y324	I316-V320 PolarHBondContact O-N 3.07Å; L317-V320 HydrophobicContact CD1-CB 4.22Å; L317-V320 HydrophobicContact CD1-CG2 4.5Å; L317-V320 PolarHBondContact O-N 2.9Å; G318-V320 PolarHBondContact O-N 2.85Å; V320-L323 PolarHBondContact O-N 2.98Å; V320-Y324 WeakPolarHBondContact O-CB 3.32Å; V320-Y324 PolarHBondContact O-N 3.03Å
321	S	89.6	Confident	85.5	Confident	2 Å²	2	50 Å²	50	1%	0.014	25%	0.254	C	S	.	.	H	α-helix	trans	-59.9	-46.1	177.2	175.8	0	0	0	0	112.2	L317 G318 T319 Y324 L325 L447 Q450	L317-S321 WeakPolarHBondContact O-CB 3.48Å; L317-S321 PolarHBondContact O-N 3.36Å; G318-S321 WeakPolarHBondContact O-CB 3.32Å; G318-S321 PolarHBondContact O-N 3.19Å; T319-S321 VanDerWaalsContact C-N 3.34Å; T319-S321 PolarHBondContact O-N 3.29Å; S321-Y324 PolarHBondContact O-N 3.44Å; S321-L325 WeakPolarHBondContact O-CB 3.1Å; S321-L325 PolarHBondContact O-N 3.29Å; S321-L447 VanDerWaalsContact OG-CD2 3.3Å; S321-L447 WeakPolarHBondContact OG-CD2 3.44Å; S321-Q450 PolarHBondContact OG-OE1 3.28Å
322	V	89.9	Confident	86.5	Confident	4 Å²	4	49.8 Å²	49.8	2%	0.024	25%	0.253	C	S	.	.	H	α-helix	trans	-66.7	-42.3	177.7	176.9	0	0	0	0	111.8	W127 M131 G318 T319 Y324 L325 I326	W127-V322 HydrophobicContact CH2-CB 4.15Å; W127-V322 HydrophobicContact CH2-CG1 3.56Å; W127-V322 HydrophobicContact CZ2-CG1 3.76Å; M131-V322 HydrophobicContact CB-CG1 4.22Å; M131-V322 HydrophobicContact CB-CG2 3.79Å; M131-V322 HydrophobicContact CG-CG1 4.18Å; M131-V322 HydrophobicContact SD-CG1 4.28Å; G318-V322 WeakPolarHBondContact O-CG2 3.47Å; G318-V322 PolarHBondContact O-N 2.81Å; T319-V322 PolarHBondContact O-N 3.06Å; V322-Y324 VanDerWaalsContact C-N 3.32Å; V322-Y324 PolarHBondContact O-N 2.93Å; V322-L325 WeakPolarHBondContact O-CB 3.13Å; V322-L325 PolarHBondContact O-N 3.48Å; V322-I326 HydrophobicContact CG1-CD1 4.18Å; V322-I326 WeakPolarHBondContact O-CG1 3.47Å; V322-I326 PolarHBondContact O-N 2.99Å
323	L	91.8	Very high	87.7	Confident	101 Å²	101	47 Å²	47	53%	0.529	23%	0.233	S	C	.	.	H	α-helix	trans	-62.2	-40.8	175.6	-71.7	174.5	0	0	0	111.7	T319 V320 L325 I326 F327	T319-L323 HydrophobicContact CG2-CD1 4.13Å; T319-L323 HydrophobicContact CG2-CG 4.47Å; T319-L323 WeakPolarHBondContact O-CB 3.49Å; T319-L323 VanDerWaalsContact O-CG 3.29Å; T319-L323 WeakPolarHBondContact O-CG 3.2Å; T319-L323 PolarHBondContact O-N 3.21Å; V320-L323 PolarHBondContact O-N 2.98Å; L323-L325 VanDerWaalsContact C-N 3.35Å; L323-I326 PolarHBondContact O-N 3.34Å; L323-F327 PolarHBondContact O-N 3.2Å
324	Y	94.1	Very high	88.6	Confident	39 Å²	39	45 Å²	45	15%	0.153	23%	0.234	C	C	.	.	H	α-helix	trans	-64.1	-40.4	174	-175.3	-95.1	0	0	0	111.9	V320 S321 V322 F327 L328 L439 I442 A443 F446	V320-Y324 WeakPolarHBondContact O-CB 3.32Å; V320-Y324 PolarHBondContact O-N 3.03Å; S321-Y324 PolarHBondContact O-N 3.44Å; V322-Y324 VanDerWaalsContact C-N 3.32Å; V322-Y324 PolarHBondContact O-N 2.93Å; Y324-F327 HydrophobicContact CD2-CD1 4.47Å; Y324-F327 HydrophobicContact CE2-CD1 4.31Å; Y324-F327 WeakPolarHBondContact O-CB 3.18Å; Y324-F327 PolarHBondContact O-N 3.29Å; Y324-L328 HydrophobicContact CE1-CD1 4.26Å; Y324-L328 WeakPolarHBondContact O-CB 3.29Å; Y324-L328 PolarHBondContact O-N 3.16Å; Y324-L439 PolarHBondContact OH-O 3.32Å; Y324-I442 HydrophobicContact CD1-CG2 4.46Å; Y324-I442 HydrophobicContact CE1-CB 4.06Å; Y324-I442 HydrophobicContact CE1-CG2 3.78Å; Y324-I442 HydrophobicContact CE2-CG2 3.86Å; Y324-I442 VanDerWaalsContact CZ-CG2 3.44Å; Y324-I442 WeakPolarHBondContact OH-CB 3.41Å; Y324-A443 HydrophobicContact CD1-CB 3.87Å; Y324-A443 HydrophobicContact CE1-CB 3.63Å; Y324-A443 VanDerWaalsContact CE1-N 3.33Å; Y324-F446 AromaticContact CD1-CD2 3.91Å; Y324-F446 HydrophobicContact CD1-CD2 3.91Å; Y324-F446 HydrophobicContact CD1-CE2 4.36Å; Y324-F446 HydrophobicContact CD2-CD2 4.21Å; Y324-F446 AromaticContact CD2-CE2 3.88Å; Y324-F446 HydrophobicContact CD2-CE2 3.88Å; Y324-F446 HydrophobicContact CE2-CE2 4.42Å; Y324-F446 AromaticContact CG-CD2 3.69Å; Y324-F446 HydrophobicContact CG-CD2 3.69Å; Y324-F446 AromaticContact CG-CE2 3.85Å; Y324-F446 HydrophobicContact CG-CE2 3.85Å
325	L	93.1	Very high	89.3	Confident	2 Å²	2	49.3 Å²	49.3	1%	0.01	25%	0.248	C	C	.	.	H	α-helix	trans	-62.7	-43.9	176.7	-170.8	69.2	0	0	0	111.8	I135 L136 S321 V322 L323 F327 L328 V329 F429 L430 L447	I135-L325 HydrophobicContact CD1-CD2 4.44Å; I135-L325 HydrophobicContact CG2-CD2 3.45Å; I135-L325 VanDerWaalsContact CG2-CD2 3.45Å; L136-L325 HydrophobicContact CD2-CD1 4.35Å; L136-L325 HydrophobicContact CD2-CD2 4.13Å; S321-L325 WeakPolarHBondContact O-CB 3.1Å; S321-L325 PolarHBondContact O-N 3.29Å; V322-L325 WeakPolarHBondContact O-CB 3.13Å; V322-L325 PolarHBondContact O-N 3.48Å; L323-L325 VanDerWaalsContact C-N 3.35Å; L325-F327 VanDerWaalsContact C-N 3.34Å; L325-F327 PolarHBondContact O-N 3.06Å; L325-L328 PolarHBondContact O-N 2.91Å; L325-V329 WeakPolarHBondContact O-CG2 3.43Å; L325-V329 PolarHBondContact O-N 2.87Å; L325-F429 HydrophobicContact CD1-CZ 3.8Å; L325-F429 HydrophobicContact CG-CZ 4.32Å; L325-L430 HydrophobicContact CD1-CD1 4.47Å; L325-L430 HydrophobicContact CD1-CD2 4.37Å; L325-L447 HydrophobicContact CD1-CD1 4.4Å
326	I	93.9	Very high	90	Very high	37 Å²	37	48.5 Å²	48.5	19%	0.19	24%	0.243	C	C	.	.	H	α-helix	trans	-58.1	-49.2	174	-68.8	167.8	0	0	0	109.5	V322 L323 L328 V329 T330 Y406 I407	V322-I326 HydrophobicContact CG1-CD1 4.18Å; V322-I326 WeakPolarHBondContact O-CG1 3.47Å; V322-I326 PolarHBondContact O-N 2.99Å; L323-I326 PolarHBondContact O-N 3.34Å; I326-L328 PolarHBondContact O-N 3.4Å; I326-V329 PolarHBondContact O-N 2.79Å; I326-T330 PolarHBondContact O-N 2.83Å; I326-T330 PolarHBondContact O-OG1 3.37Å; I326-Y406 HydrophobicContact CG2-CD1 4.43Å; I326-Y406 HydrophobicContact CG2-CE1 3.91Å; I326-I407 HydrophobicContact CG1-CD1 3.96Å
327	F	95.4	Very high	90.4	Very high	114 Å²	114	43.5 Å²	43.5	50%	0.5	22%	0.224	S	C	.	.	H	α-helix	trans	-57	-45.7	176.6	169.2	-98.9	0	0	0	112.6	L323 Y324 L325 T330 F331	L323-F327 PolarHBondContact O-N 3.2Å; Y324-F327 HydrophobicContact CD2-CD1 4.47Å; Y324-F327 HydrophobicContact CE2-CD1 4.31Å; Y324-F327 WeakPolarHBondContact O-CB 3.18Å; Y324-F327 PolarHBondContact O-N 3.29Å; L325-F327 VanDerWaalsContact C-N 3.34Å; L325-F327 PolarHBondContact O-N 3.06Å; F327-T330 PolarHBondContact O-N 3.1Å; F327-F331 VanDerWaalsContact O-CB 3.28Å; F327-F331 WeakPolarHBondContact O-CB 3.22Å; F327-F331 PolarHBondContact O-N 3.46Å
328	L	94.4	Very high	91	Very high	0 Å²	0	48 Å²	48	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-59.3	-48.9	178.1	178.9	154.1	0	0	0	111.1	Y324 L325 I326 F331 K332 L430 F433 L439 A443	Y324-L328 HydrophobicContact CE1-CD1 4.26Å; Y324-L328 WeakPolarHBondContact O-CB 3.29Å; Y324-L328 PolarHBondContact O-N 3.16Å; L325-L328 PolarHBondContact O-N 2.91Å; I326-L328 PolarHBondContact O-N 3.4Å; L328-F331 PolarHBondContact O-N 3.24Å; L328-K332 HydrophobicContact CD2-CG 4.18Å; L328-K332 HydrophobicContact CG-CG 4.47Å; L328-K332 WeakPolarHBondContact O-CB 3.28Å; L328-K332 WeakPolarHBondContact O-CG 3.33Å; L328-K332 PolarHBondContact O-N 3.21Å; L328-L430 HydrophobicContact CD2-CD2 4.4Å; L328-F433 HydrophobicContact CD2-CE2 4.42Å; L328-L439 HydrophobicContact CD1-CB 4.2Å; L328-L439 WeakPolarHBondContact CD1-O 3.26Å; L328-A443 HydrophobicContact CD1-CB 3.62Å
329	V	94.8	Very high	91.3	Very high	3 Å²	3	50.7 Å²	50.7	2%	0.018	26%	0.255	C	S	.	.	H	α-helix	trans	-63.3	-45.3	-179.1	170.9	0	0	0	0	110.6	L325 I326 F331 K332 A333 I407 L410 V411 F429	L325-V329 WeakPolarHBondContact O-CG2 3.43Å; L325-V329 PolarHBondContact O-N 2.87Å; I326-V329 PolarHBondContact O-N 2.79Å; V329-F331 PolarHBondContact O-N 2.88Å; V329-K332 PolarHBondContact O-N 3.47Å; V329-A333 VanDerWaalsContact O-CB 3.25Å; V329-A333 WeakPolarHBondContact O-CB 3.48Å; V329-A333 PolarHBondContact O-N 2.86Å; V329-I407 HydrophobicContact CG2-CG2 4.38Å; V329-L410 HydrophobicContact CG1-CB 3.72Å; V329-L410 HydrophobicContact CG1-CD1 4.14Å; V329-V411 HydrophobicContact CG1-CG2 3.73Å; V329-V411 HydrophobicContact CG2-CG2 4Å; V329-F429 HydrophobicContact CG2-CE2 3.93Å; V329-F429 HydrophobicContact CG2-CZ 3.7Å
330	T	95.1	Very high	91.5	Very high	45 Å²	45	51.8 Å²	51.8	28%	0.276	26%	0.259	S	S	.	.	H	α-helix	trans	-61.3	-45.7	176.6	-51.7	0	0	0	0	111.4	I326 F327 A333 V334 Y406	I326-T330 PolarHBondContact O-N 2.83Å; I326-T330 PolarHBondContact O-OG1 3.37Å; F327-T330 PolarHBondContact O-N 3.1Å; T330-A333 PolarHBondContact O-N 2.87Å; T330-V334 WeakPolarHBondContact O-CG2 3.39Å; T330-V334 PolarHBondContact O-N 3.45Å; T330-Y406 PolarHBondContact OG1-OH 2.87Å
331	F	94.4	Very high	91.4	Very high	69 Å²	69	53.5 Å²	53.5	30%	0.303	26%	0.262	S	S	.	.	H	α-helix	trans	-64.4	-44.7	-179.7	-177.7	-97.2	0	0	0	112.1	F327 L328 V329 V334 R335 L439	F327-F331 VanDerWaalsContact O-CB 3.28Å; F327-F331 WeakPolarHBondContact O-CB 3.22Å; F327-F331 PolarHBondContact O-N 3.46Å; L328-F331 PolarHBondContact O-N 3.24Å; V329-F331 PolarHBondContact O-N 2.88Å; F331-V334 PolarHBondContact O-N 2.78Å; F331-R335 HydrophobicContact CD1-CG 4.35Å; F331-R335 HydrophobicContact CE1-CG 4.02Å; F331-R335 HydrophobicContact CZ-CG 4.2Å; F331-R335 WeakPolarHBondContact O-CG 3.4Å; F331-R335 PolarHBondContact O-N 2.94Å; F331-R335 VanDerWaalsContact O-N 3.12Å; F331-L439 HydrophobicContact CD1-CD2 3.46Å; F331-L439 VanDerWaalsContact CD1-CD2 3.46Å; F331-L439 HydrophobicContact CE1-CD2 3.76Å; F331-L439 HydrophobicContact CG-CD2 4.27Å
332	K	91.1	Very high	91.2	Very high	10 Å²	10	58.8 Å²	58.8	4%	0.043	29%	0.285	C	S	.	.	H	α-helix	trans	-65.8	-39.2	176.9	-70.4	-71	-175.5	176.8	0	111.3	L328 V329 V334 R335 L336 F433 D437	L328-K332 HydrophobicContact CD2-CG 4.18Å; L328-K332 HydrophobicContact CG-CG 4.47Å; L328-K332 WeakPolarHBondContact O-CB 3.28Å; L328-K332 WeakPolarHBondContact O-CG 3.33Å; L328-K332 PolarHBondContact O-N 3.21Å; V329-K332 PolarHBondContact O-N 3.47Å; K332-V334 PolarHBondContact O-N 2.98Å; K332-R335 PolarHBondContact O-N 3.48Å; K332-L336 HydrophobicContact CB-CD1 4.42Å; K332-L336 WeakPolarHBondContact O-CB 3.3Å; K332-L336 WeakPolarHBondContact O-CG 3.32Å; K332-L336 PolarHBondContact O-N 2.8Å; K332-F433 HydrophobicContact CB-CZ 4.37Å; K332-F433 HydrophobicContact CD-CE1 4.11Å; K332-F433 HydrophobicContact CG-CE1 4.27Å; K332-F433 HydrophobicContact CG-CZ 4.19Å; K332-D437 WeakPolarHBondContact CE-OD2 3.29Å; K332-D437 IonicContact NZ-OD1 2.8Å; K332-D437 PolarHBondContact NZ-OD1 3.34Å; K332-D437 IonicContact NZ-OD2 2.92Å; K332-D437 PolarHBondContact NZ-OD2 3.37Å
333	A	92.4	Very high	91.1	Very high	2 Å²	2	61.5 Å²	61.5	2%	0.017	30%	0.298	C	S	.	.	H	α-helix	trans	-62	-42.7	175.9	0	0	0	0	0	112.5	V329 T330 R335 G337 L410	V329-A333 VanDerWaalsContact O-CB 3.25Å; V329-A333 WeakPolarHBondContact O-CB 3.48Å; V329-A333 PolarHBondContact O-N 2.86Å; T330-A333 PolarHBondContact O-N 2.87Å; A333-R335 VanDerWaalsContact C-N 3.32Å; A333-R335 PolarHBondContact O-N 3.44Å; A333-G337 PolarHBondContact O-N 3.13Å; A333-L410 HydrophobicContact CB-CB 4.37Å; A333-L410 HydrophobicContact CB-CD2 4.24Å
334	V	92.4	Very high	90.9	Very high	117 Å²	117	63.8 Å²	63.8	71%	0.709	30%	0.299	S	S	*	.	H	α-helix	trans	-64.7	-35.9	176.1	172	0	0	0	0	111.9	T330 F331 K332	T330-V334 WeakPolarHBondContact O-CG2 3.39Å; T330-V334 PolarHBondContact O-N 3.45Å; F331-V334 PolarHBondContact O-N 2.78Å; K332-V334 PolarHBondContact O-N 2.98Å
335	R	89.7	Confident	90.5	Very high	158 Å²	158	69.3 Å²	69.3	60%	0.596	32%	0.324	S	S	*	.	H	α-helix	trans	-74.8	-40.7	179.7	-74.6	-73.3	-173	170.1	1	113.4	F331 K332 A333	F331-R335 HydrophobicContact CD1-CG 4.35Å; F331-R335 HydrophobicContact CE1-CG 4.02Å; F331-R335 HydrophobicContact CZ-CG 4.2Å; F331-R335 WeakPolarHBondContact O-CG 3.4Å; F331-R335 PolarHBondContact O-N 2.94Å; F331-R335 VanDerWaalsContact O-N 3.12Å; K332-R335 PolarHBondContact O-N 3.48Å; A333-R335 VanDerWaalsContact C-N 3.32Å; A333-R335 PolarHBondContact O-N 3.44Å
336	L	86.7	Confident	90	Very high	34 Å²	34	75.3 Å²	75.3	18%	0.178	36%	0.355	C	S	.	.	H	α-helix	trans	-82.7	-25.6	-176.9	-67.6	165.2	0	0	0	111.7	V253 K332 H339	V253-L336 HydrophobicContact CG2-CD1 4.13Å; V253-L336 HydrophobicContact CG2-CD2 4.1Å; K332-L336 HydrophobicContact CB-CD1 4.42Å; K332-L336 WeakPolarHBondContact O-CB 3.3Å; K332-L336 WeakPolarHBondContact O-CG 3.32Å; K332-L336 PolarHBondContact O-N 2.8Å; L336-H339 PolarHBondContact O-CE1 3.29Å
337	G	87.4	Confident	89.4	Confident	27 Å²	27	77.8 Å²	77.8	28%	0.278	37%	0.374	S	S	.	.			trans	78.9	-176.9	-174.7	0	0	0	0	0	112.2	A333 S414	A333-G337 PolarHBondContact O-N 3.13Å; G337-S414 VanDerWaalsContact O-CA 3.25Å; G337-S414 WeakPolarHBondContact O-CA 3.35Å; G337-S414 WeakPolarHBondContact O-CB 3.41Å
338	F	89.7	Confident	88.9	Confident	141 Å²	141	74.9 Å²	74.9	62%	0.618	37%	0.365	S	S	*	.			trans	-105.9	126.1	-179	-65.4	-73.2	0	0	0	110.6	L410 A413	F338-L410 HydrophobicContact CE1-CD2 3.96Å; F338-L410 HydrophobicContact CZ-CD2 4.22Å; F338-A413 HydrophobicContact CD1-CB 3.86Å; F338-A413 HydrophobicContact CE1-CB 4.37Å
339	H	89.3	Confident	88.3	Confident	57 Å²	57	82.3 Å²	82.3	26%	0.264	40%	0.4	S	S	.	.			trans	-124.8	86.9	-179.2	-57.5	101	0	0	0	109.1	L336 A413 S417 K422	L336-H339 PolarHBondContact O-CE1 3.29Å; H339-A413 PolarHBondContact N-O 3.17Å; H339-S417 WeakPolarHBondContact CB-O 3.42Å; H339-K422 VanDerWaalsContact O-CE 3.28Å; H339-K422 WeakPolarHBondContact O-CE 3.44Å; H339-K422 PolarHBondContact O-NZ 3.22Å
340	L	87.1	Confident	87.8	Confident	59 Å²	59	85 Å²	85	31%	0.309	41%	0.411	S	S	.	.			trans	-128.3	124.1	-178.7	-70.5	175.2	0	0	0	109.9	F342 F412 A413	L340-F342 HydrophobicContact CB-CZ 4.34Å; L340-F342 HydrophobicContact CD1-CZ 4.35Å; L340-F412 HydrophobicContact CD2-CD1 4.16Å; L340-F412 HydrophobicContact CD2-CE1 4.18Å; L340-A413 HydrophobicContact CD1-CB 3.79Å; L340-A413 HydrophobicContact CD2-CB 3.94Å; L340-A413 HydrophobicContact CG-CB 3.91Å
341	E	86.6	Confident	87.5	Confident	102 Å²	102	83.1 Å²	83.1	48%	0.477	40%	0.4	S	S	.	.			trans	-128	135.8	165.6	-66.9	-175.1	-179.9	0	0	107.9	H343 F351	E341-H343 IonicContact OE2-NE2 3.79Å; E341-F351 HydrophobicContact CB-CD1 3.95Å; E341-F351 HydrophobicContact CB-CD2 4.01Å; E341-F351 HydrophobicContact CB-CE1 3.81Å; E341-F351 HydrophobicContact CB-CE2 3.87Å; E341-F351 HydrophobicContact CB-CG 4.05Å; E341-F351 HydrophobicContact CB-CZ 3.77Å; E341-F351 VanDerWaalsContact CD-CE2 3.4Å; E341-F351 HydrophobicContact CG-CD2 4.43Å; E341-F351 HydrophobicContact CG-CE1 4Å; E341-F351 HydrophobicContact CG-CE2 3.79Å; E341-F351 HydrophobicContact CG-CZ 3.54Å; E341-F351 WeakPolarHBondContact OE2-CE2 3.27Å
342	F	86.8	Confident	87.2	Confident	114 Å²	114	80 Å²	80	50%	0.5	39%	0.386	S	S	.	.			trans	-101.6	106.6	-171.2	-62.6	-76.7	0	0	0	110.5	F147 L340 E354	F147-F342 AromaticContact CD1-CE1 3.91Å; F147-F342 HydrophobicContact CD1-CE1 3.91Å; F147-F342 AromaticContact CE1-CE1 3.97Å; F147-F342 HydrophobicContact CE1-CE1 3.97Å; L340-F342 HydrophobicContact CB-CZ 4.34Å; L340-F342 HydrophobicContact CD1-CZ 4.35Å; F342-E354 HydrophobicContact CD1-CG 4.36Å; F342-E354 WeakPolarHBondContact CD1-OE1 3.48Å
343	H	87.8	Confident	87.2	Confident	61 Å²	61	80.3 Å²	80.3	28%	0.282	39%	0.389	S	S	.	.			trans	-115.8	116.2	172.1	-61.7	-78.9	0	0	0	109.8	E341 I346 P353 E354	E341-H343 IonicContact OE2-NE2 3.79Å; H343-I346 WeakPolarHBondContact CB-O 3.06Å; H343-P353 CarbonylContact O-C 3.58Å; H343-P353 VanDerWaalsContact O-CA 3.27Å; H343-P353 WeakPolarHBondContact O-CA 3.47Å; H343-E354 WeakPolarHBondContact O-CG 3.42Å; H343-E354 PolarHBondContact O-N 2.98Å
344	W	86.9	Confident	87.1	Confident	148 Å²	148	80.4 Å²	80.4	56%	0.561	39%	0.389	S	S	*	.	S	Bend	trans	-69.2	-46.2	-168.4	-70.7	92.6	0	0	0	114.2	E354 I355	W344-E354 HydrophobicContact CE3-CB 4.36Å; W344-I355 HydrophobicContact CE3-CD1 4.35Å; W344-I355 PolarHBondContact O-N 3.49Å
345	F	84.8	Confident	87	Confident	155 Å²	155	78.1 Å²	78.1	68%	0.68	37%	0.372	S	S	*	.	S	Bend	trans	-130.8	-25	-171.6	-58.2	-73.6	0	0	0	114	I355	F345-I355 HydrophobicContact CE1-CD1 3.93Å; F345-I355 HydrophobicContact CZ-CD1 4.27Å
346	I	83.6	Confident	87	Confident	128 Å²	128	72.6 Å²	72.6	66%	0.656	35%	0.351	S	S	*	.			trans	-99.6	122.1	-172.9	-54.9	170.7	0	0	0	107.9	H343	H343-I346 WeakPolarHBondContact CB-O 3.06Å
347	P	82.1	Confident	87.1	Confident	89 Å²	89	79 Å²	79	58%	0.578	38%	0.378	S	S	*	.			trans	-69	142	172.9	29.4	-33.2	0	0	0	110.2
348	T	83.9	Confident	87.1	Confident	53 Å²	53	81.1 Å²	81.1	33%	0.325	38%	0.381	S	S	.	.			trans	-107.1	171.4	166.6	66.4	0	0	0	0	109.4	F350 F351	T348-F350 PolarHBondContact O-N 3.04Å; T348-F351 PolarHBondContact N-O 2.66Å; T348-F351 VanDerWaalsContact N-O 3.09Å; T348-F351 WeakPolarHBondContact OG1-CB 3.35Å; T348-F351 PolarHBondContact OG1-N 2.85Å; T348-F351 PolarHBondContact OG1-O 2.83Å
349	E	81.6	Confident	87.2	Confident	157 Å²	157	78.4 Å²	78.4	73%	0.734	37%	0.369	S	S	*	.	S	Bend	trans	-58	-38	-179	-171.9	176.5	178.3	0	0	112.4	S421	E349-S421 WeakPolarHBondContact O-CB 3.28Å; E349-S421 PolarHBondContact O-OG 3.38Å
350	F	84.8	Confident	87.3	Confident	58 Å²	58	76 Å²	76	25%	0.254	36%	0.359	S	S	.	.	S	Bend	trans	-103.1	-29.2	-176.2	-58.3	-68.8	0	0	0	113.6	T348 S417 P418 P419 S421 K422	T348-F350 PolarHBondContact O-N 3.04Å; F350-S417 WeakPolarHBondContact CB-OG 3.22Å; F350-S417 PolarHBondContact O-OG 3.08Å; F350-P418 HydrophobicContact CD1-CB 4.3Å; F350-P418 HydrophobicContact CD2-CB 4.28Å; F350-P418 HydrophobicContact CD2-CG 3.98Å; F350-P418 HydrophobicContact CE1-CB 4.45Å; F350-P418 HydrophobicContact CE2-CB 4.42Å; F350-P418 HydrophobicContact CE2-CG 4.4Å; F350-P418 HydrophobicContact CG-CB 4.23Å; F350-P418 HydrophobicContact CG-CG 4.17Å; F350-P419 VanDerWaalsContact CE1-O 3.28Å; F350-P419 WeakPolarHBondContact CE1-O 3.45Å; F350-S421 WeakPolarHBondContact O-CA 3.39Å; F350-K422 PolarHBondContact O-N 2.81Å
351	F	87.6	Confident	87.6	Confident	7 Å²	7	74 Å²	74	3%	0.031	35%	0.347	C	S	.	.			trans	-111.5	137.7	-174.2	-58.1	-90	0	0	0	113.2	E341 T348 S417 K422	E341-F351 HydrophobicContact CB-CD1 3.95Å; E341-F351 HydrophobicContact CB-CD2 4.01Å; E341-F351 HydrophobicContact CB-CE1 3.81Å; E341-F351 HydrophobicContact CB-CE2 3.87Å; E341-F351 HydrophobicContact CB-CG 4.05Å; E341-F351 HydrophobicContact CB-CZ 3.77Å; E341-F351 VanDerWaalsContact CD-CE2 3.4Å; E341-F351 HydrophobicContact CG-CD2 4.43Å; E341-F351 HydrophobicContact CG-CE1 4Å; E341-F351 HydrophobicContact CG-CE2 3.79Å; E341-F351 HydrophobicContact CG-CZ 3.54Å; E341-F351 WeakPolarHBondContact OE2-CE2 3.27Å; T348-F351 PolarHBondContact N-O 2.66Å; T348-F351 VanDerWaalsContact N-O 3.09Å; T348-F351 WeakPolarHBondContact OG1-CB 3.35Å; T348-F351 PolarHBondContact OG1-N 2.85Å; T348-F351 PolarHBondContact OG1-O 2.83Å; F351-S417 WeakPolarHBondContact CZ-O 3Å; F351-K422 HydrophobicContact CD1-CD 4.17Å
352	V	88.3	Confident	88	Confident	4 Å²	4	69.1 Å²	69.1	2%	0.024	33%	0.325	C	S	.	.			trans	-85.6	141.1	176.9	174.4	0	0	0	0	109.2	R356 K422 D423	V352-R356 HydrophobicContact CG1-CG 4.35Å; V352-K422 HydrophobicContact CB-CB 4.43Å; V352-K422 HydrophobicContact CG2-CB 3.77Å; V352-D423 HydrophobicContact CG2-CB 4.43Å; V352-D423 WeakPolarHBondContact CG2-OD1 3.37Å
353	P	91.3	Very high	88.3	Confident	15 Å²	15	64.6 Å²	64.6	10%	0.097	31%	0.307	C	S	.	.			trans	-65.5	149.5	-179.7	25.5	-33.9	0	0	0	112.5	G146 H343 I355 R356	G146-P353 WeakPolarHBondContact CA-O 3.22Å; H343-P353 CarbonylContact O-C 3.58Å; H343-P353 VanDerWaalsContact O-CA 3.27Å; H343-P353 WeakPolarHBondContact O-CA 3.47Å; P353-I355 VanDerWaalsContact C-N 3.26Å; P353-I355 PolarHBondContact O-N 2.94Å; P353-R356 HydrophobicContact CG-CG 3.83Å
354	E	90.6	Very high	88.6	Confident	4 Å²	4	61.7 Å²	61.7	2%	0.019	29%	0.293	C	S	.	.	S	Bend	trans	-65.5	-27.6	-178.5	-68.1	-60.4	139.6	0	0	113.7	G146 F147 T148 T149 F342 H343 W344	G146-E354 CarbonylContact C-O 3.45Å; G146-E354 WeakPolarHBondContact CA-O 3.41Å; F147-E354 WeakPolarHBondContact CB-OE2 3.08Å; T148-E354 VanDerWaalsContact CB-OE2 3.29Å; T148-E354 WeakPolarHBondContact CB-OE2 3.33Å; T148-E354 PolarHBondContact N-OE2 2.79Å; T148-E354 PolarHBondContact OG1-OE2 2.84Å; T149-E354 PolarHBondContact N-O 2.83Å; T149-E354 PolarHBondContact OG1-O 2.72Å; F342-E354 HydrophobicContact CD1-CG 4.36Å; F342-E354 WeakPolarHBondContact CD1-OE1 3.48Å; H343-E354 WeakPolarHBondContact O-CG 3.42Å; H343-E354 PolarHBondContact O-N 2.98Å; W344-E354 HydrophobicContact CE3-CB 4.36Å
355	I	90.1	Very high	88.9	Confident	69 Å²	69	54.7 Å²	54.7	35%	0.354	27%	0.267	S	S	.	.	S	Bend	trans	-123	108.4	178.6	-54.4	177.3	0	0	0	108.7	W344 F345 P353	W344-I355 HydrophobicContact CE3-CD1 4.35Å; W344-I355 PolarHBondContact O-N 3.49Å; F345-I355 HydrophobicContact CE1-CD1 3.93Å; F345-I355 HydrophobicContact CZ-CD1 4.27Å; P353-I355 VanDerWaalsContact C-N 3.26Å; P353-I355 PolarHBondContact O-N 2.94Å
356	R	90.3	Very high	89.4	Confident	42 Å²	42	47.3 Å²	47.3	16%	0.158	23%	0.234	C	C	.	.			trans	-112.2	141.8	172.8	-70.6	-178.5	83	146.5	10.6	111.2	K143 Q144 A145 V352 P353 Q358 F359 D423	K143-R356 VanDerWaalsContact O-CD 3.25Å; K143-R356 WeakPolarHBondContact O-CD 3.3Å; K143-R356 PolarHBondContact O-NH1 2.82Å; Q144-R356 WeakPolarHBondContact O-CB 3.5Å; Q144-R356 WeakPolarHBondContact O-CD 3.41Å; A145-R356 WeakPolarHBondContact O-CB 3.41Å; A145-R356 PolarHBondContact O-N 3.45Å; V352-R356 HydrophobicContact CG1-CG 4.35Å; P353-R356 HydrophobicContact CG-CG 3.83Å; R356-Q358 PolarHBondContact O-N 3.39Å; R356-F359 PolarHBondContact O-N 3.44Å; R356-D423 IonicContact CZ-OD1 3.14Å; R356-D423 IonicContact NH1-OD1 2.84Å; R356-D423 PolarHBondContact NH1-OD1 3.23Å; R356-D423 IonicContact NH2-OD1 3.99Å
357	F	87.7	Confident	89.8	Confident	169 Å²	169	41.2 Å²	41.2	74%	0.741	20%	0.203	S	C	*	.	T	Hydrogen-bonded Turn	trans	-66.4	-18.1	172.3	-68.7	-73.3	0	0	0	112.6	F359 P360 M561	F357-F359 PolarHBondContact O-N 3.09Å; F357-P360 WeakPolarHBondContact O-CD 3.35Å; F357-M561 WeakPolarHBondContact O-CE 3.2Å; F357-M561 VanDerWaalsContact O-SD 3.41Å
358	Q	89.3	Confident	90.2	Very high	71 Å²	71	38.3 Å²	38.3	33%	0.332	18%	0.182	S	C	.	.	T	Hydrogen-bonded Turn	trans	-76.2	8.7	176.1	-59.2	86.3	3.7	0	0	115.1	Q144 R356 P360 Q361 M561	Q144-Q358 HydrophobicContact CB-CB 4.42Å; Q144-Q358 CarbonylContact O-C 3.59Å; Q144-Q358 WeakPolarHBondContact O-CB 3.46Å; R356-Q358 PolarHBondContact O-N 3.39Å; Q358-P360 VanDerWaalsContact C-N 3.27Å; Q358-P360 WeakPolarHBondContact O-CD 3.3Å; Q358-P360 VanDerWaalsContact O-N 3.13Å; Q358-Q361 WeakPolarHBondContact O-CB 3.47Å; Q358-Q361 WeakPolarHBondContact O-CG 3.19Å; Q358-Q361 PolarHBondContact O-N 2.96Å; Q358-Q361 VanDerWaalsContact O-N 3.09Å; Q358-M561 HydrophobicContact CB-SD 4.44Å
359	F	90.1	Very high	90.7	Very high	84 Å²	84	35.9 Å²	35.9	37%	0.368	17%	0.168	S	C	.	.	H	α-helix	trans	-52.3	-28.8	175.9	82.3	-91.9	0	0	0	116.3	A145 T149 V153 R356 F357 Q361 L362 T363	A145-F359 HydrophobicContact CB-CB 3.72Å; T149-F359 HydrophobicContact CG2-CB 4.03Å; T149-F359 HydrophobicContact CG2-CG 4.47Å; V153-F359 HydrophobicContact CG2-CD2 4.37Å; R356-F359 PolarHBondContact O-N 3.44Å; F357-F359 PolarHBondContact O-N 3.09Å; F359-Q361 PolarHBondContact O-N 3.45Å; F359-L362 WeakPolarHBondContact O-CB 3.15Å; F359-L362 PolarHBondContact O-N 3.44Å; F359-T363 HydrophobicContact CD2-CG2 4.48Å; F359-T363 PolarHBondContact O-N 3.24Å
360	P	92.4	Very high	91.2	Very high	8 Å²	8	28.4 Å²	28.4	5%	0.052	13%	0.133	C	C	.	.	H	α-helix	trans	-63.2	-25.1	177.6	-26.4	38.9	0	0	0	113.1	F357 Q358 L362 T363 G364 V557 Q558 M561	F357-P360 WeakPolarHBondContact O-CD 3.35Å; Q358-P360 VanDerWaalsContact C-N 3.27Å; Q358-P360 WeakPolarHBondContact O-CD 3.3Å; Q358-P360 VanDerWaalsContact O-N 3.13Å; P360-L362 PolarHBondContact O-N 3.43Å; P360-T363 WeakPolarHBondContact CA-OG1 3.26Å; P360-T363 PolarHBondContact O-N 3.34Å; P360-T363 VanDerWaalsContact O-N 3.15Å; P360-T363 PolarHBondContact O-OG1 3.41Å; P360-G364 PolarHBondContact O-N 3.39Å; P360-G364 VanDerWaalsContact O-N 3.14Å; P360-V557 HydrophobicContact CB-CB 4.18Å; P360-V557 HydrophobicContact CB-CG1 3.49Å; P360-V557 VanDerWaalsContact CB-CG1 3.49Å; P360-V557 HydrophobicContact CG-CB 4.44Å; P360-V557 HydrophobicContact CG-CG1 3.41Å; P360-V557 VanDerWaalsContact CG-CG1 3.41Å; P360-Q558 PolarHBondContact O-NE2 3.42Å; P360-M561 HydrophobicContact CB-SD 4.33Å; P360-M561 HydrophobicContact CG-CE 3.77Å; P360-M561 HydrophobicContact CG-SD 3.94Å
361	Q	92.7	Very high	91.5	Very high	15 Å²	15	27.2 Å²	27.2	7%	0.07	13%	0.128	C	C	.	.	H	α-helix	trans	-61.2	-36.9	175	-59.1	-174	3.6	0	0	111.1	W140 Q144 Q358 F359 V365	W140-Q361 HydrophobicContact CH2-CB 4.42Å; Q144-Q361 HydrophobicContact CB-CB 4.34Å; Q144-Q361 VanDerWaalsContact CD-OE1 3.3Å; Q358-Q361 WeakPolarHBondContact O-CB 3.47Å; Q358-Q361 WeakPolarHBondContact O-CG 3.19Å; Q358-Q361 PolarHBondContact O-N 2.96Å; Q358-Q361 VanDerWaalsContact O-N 3.09Å; F359-Q361 PolarHBondContact O-N 3.45Å; Q361-V365 WeakPolarHBondContact O-CG2 3.47Å; Q361-V365 PolarHBondContact O-N 3.45Å
362	L	94.5	Very high	91.5	Very high	0 Å²	0	27 Å²	27	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-68.3	-39.7	174.9	175.1	63.7	0	0	0	111.7	A145 V153 I154 F359 P360 G364 V365 L366	A145-L362 HydrophobicContact CB-CB 4.28Å; A145-L362 HydrophobicContact CB-CD2 3.73Å; V153-L362 HydrophobicContact CB-CD2 3.98Å; V153-L362 HydrophobicContact CG1-CD2 3.82Å; V153-L362 HydrophobicContact CG1-CG 4.02Å; I154-L362 HydrophobicContact CG1-CD2 4.46Å; F359-L362 WeakPolarHBondContact O-CB 3.15Å; F359-L362 PolarHBondContact O-N 3.44Å; P360-L362 PolarHBondContact O-N 3.43Å; L362-G364 VanDerWaalsContact C-N 3.32Å; L362-G364 PolarHBondContact O-N 3.01Å; L362-V365 PolarHBondContact O-N 3.07Å; L362-L366 HydrophobicContact CD1-CD1 3.77Å; L362-L366 HydrophobicContact CD1-CD2 4.2Å; L362-L366 HydrophobicContact CD1-CG 3.74Å; L362-L366 HydrophobicContact CD2-CD1 4.29Å; L362-L366 HydrophobicContact CG-CD1 3.67Å; L362-L366 HydrophobicContact CG-CG 4.1Å; L362-L366 WeakPolarHBondContact O-CB 3.27Å; L362-L366 VanDerWaalsContact O-CG 3.25Å; L362-L366 WeakPolarHBondContact O-CG 3.24Å; L362-L366 PolarHBondContact O-N 3.03Å
363	T	94.4	Very high	91.5	Very high	20 Å²	20	26.8 Å²	26.8	12%	0.123	13%	0.125	C	C	.	.	H	α-helix	trans	-63	-39.2	178.7	58	0	0	0	0	111.7	V153 M157 F359 P360 L366 T367 N554	V153-T363 HydrophobicContact CG1-CG2 3.63Å; M157-T363 HydrophobicContact CG-CG2 4.39Å; M157-T363 HydrophobicContact SD-CG2 4.37Å; F359-T363 HydrophobicContact CD2-CG2 4.48Å; F359-T363 PolarHBondContact O-N 3.24Å; P360-T363 WeakPolarHBondContact CA-OG1 3.26Å; P360-T363 PolarHBondContact O-N 3.34Å; P360-T363 VanDerWaalsContact O-N 3.15Å; P360-T363 PolarHBondContact O-OG1 3.41Å; T363-L366 PolarHBondContact O-N 3.13Å; T363-T367 WeakPolarHBondContact O-CB 3.46Å; T363-T367 PolarHBondContact O-N 3.05Å; T363-T367 PolarHBondContact O-OG1 2.88Å; T363-N554 WeakPolarHBondContact CB-OD1 3.38Å; T363-N554 PolarHBondContact OG1-OD1 3.09Å
364	G	92.9	Very high	91.1	Very high	0 Å²	0	26.9 Å²	26.9	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-60.3	-48.1	172.9	0	0	0	0	0	112.3	P360 L362 T367 L368	P360-G364 PolarHBondContact O-N 3.39Å; P360-G364 VanDerWaalsContact O-N 3.14Å; L362-G364 VanDerWaalsContact C-N 3.32Å; L362-G364 PolarHBondContact O-N 3.01Å; G364-T367 PolarHBondContact O-N 2.96Å; G364-L368 PolarHBondContact O-N 2.77Å
365	V	93.6	Very high	90.6	Very high	0 Å²	0	28.6 Å²	28.6	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-60.4	-46.9	177.4	169.1	0	0	0	0	112	W140 Q361 L362 T367 L368 A369 I506 R507	W140-V365 HydrophobicContact CZ3-CG2 4.02Å; Q361-V365 WeakPolarHBondContact O-CG2 3.47Å; Q361-V365 PolarHBondContact O-N 3.45Å; L362-V365 PolarHBondContact O-N 3.07Å; V365-T367 VanDerWaalsContact C-N 3.29Å; V365-T367 PolarHBondContact O-N 3.36Å; V365-L368 PolarHBondContact O-N 3.48Å; V365-A369 PolarHBondContact O-N 3.45Å; V365-I506 HydrophobicContact CB-CG2 4.16Å; V365-I506 HydrophobicContact CG1-CG2 4.05Å; V365-I506 HydrophobicContact CG2-CB 4.49Å; V365-I506 HydrophobicContact CG2-CG2 4Å; V365-R507 HydrophobicContact CG2-CB 4.24Å
366	L	94.6	Very high	90.4	Very high	0 Å²	0	25.3 Å²	25.3	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-66.8	-31.2	-179.6	-68.6	171.4	0	0	0	112.8	I138 V153 I154 M157 L362 T363 L368 A369 F370	I138-L366 HydrophobicContact CD1-CD2 3.73Å; V153-L366 HydrophobicContact CG1-CD1 3.8Å; I154-L366 HydrophobicContact CB-CD1 4.35Å; I154-L366 HydrophobicContact CG1-CD1 3.8Å; I154-L366 HydrophobicContact CG1-CD2 3.95Å; I154-L366 HydrophobicContact CG1-CG 4.48Å; M157-L366 HydrophobicContact CB-CB 4.21Å; M157-L366 HydrophobicContact CB-CD1 4.02Å; M157-L366 HydrophobicContact CG-CB 4.4Å; M157-L366 HydrophobicContact CG-CD1 4.04Å; L362-L366 HydrophobicContact CD1-CD1 3.77Å; L362-L366 HydrophobicContact CD1-CD2 4.2Å; L362-L366 HydrophobicContact CD1-CG 3.74Å; L362-L366 HydrophobicContact CD2-CD1 4.29Å; L362-L366 HydrophobicContact CG-CD1 3.67Å; L362-L366 HydrophobicContact CG-CG 4.1Å; L362-L366 WeakPolarHBondContact O-CB 3.27Å; L362-L366 VanDerWaalsContact O-CG 3.25Å; L362-L366 WeakPolarHBondContact O-CG 3.24Å; L362-L366 PolarHBondContact O-N 3.03Å; T363-L366 PolarHBondContact O-N 3.13Å; L366-L368 VanDerWaalsContact C-N 3.27Å; L366-L368 PolarHBondContact O-N 3.13Å; L366-A369 PolarHBondContact O-N 3.33Å; L366-F370 HydrophobicContact CB-CD2 4.32Å; L366-F370 HydrophobicContact CB-CE2 4.48Å; L366-F370 HydrophobicContact CD2-CE2 4.08Å; L366-F370 VanDerWaalsContact O-CD2 3.32Å; L366-F370 WeakPolarHBondContact O-CD2 3.37Å; L366-F370 PolarHBondContact O-N 2.87Å
367	T	93.6	Very high	90	Very high	0 Å²	0	23.3 Å²	23.3	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-62	-39	176.9	-55.2	0	0	0	0	111.1	M157 T363 G364 V365 G510 V518 F519 N554	M157-T367 VanDerWaalsContact CE-OG1 3.26Å; M157-T367 WeakPolarHBondContact CE-OG1 3.42Å; T363-T367 WeakPolarHBondContact O-CB 3.46Å; T363-T367 PolarHBondContact O-N 3.05Å; T363-T367 PolarHBondContact O-OG1 2.88Å; G364-T367 PolarHBondContact O-N 2.96Å; V365-T367 VanDerWaalsContact C-N 3.29Å; V365-T367 PolarHBondContact O-N 3.36Å; T367-G510 VanDerWaalsContact CG2-O 3.23Å; T367-G510 WeakPolarHBondContact CG2-O 3.35Å; T367-V518 HydrophobicContact CG2-CG2 4.36Å; T367-F519 HydrophobicContact CG2-CE2 4.07Å; T367-F519 HydrophobicContact CG2-CZ 4.48Å; T367-N554 PolarHBondContact OG1-ND2 3.45Å
368	L	90.9	Very high	89.6	Confident	28 Å²	28	18 Å²	18	15%	0.147	9%	0.094	C	C	.	.	H	α-helix	trans	-75.8	-36.6	172.5	-163.7	63.3	0	0	0	112.2	G364 V365 L366 F370 F371 I506	G364-L368 PolarHBondContact O-N 2.77Å; V365-L368 PolarHBondContact O-N 3.48Å; L366-L368 VanDerWaalsContact C-N 3.27Å; L366-L368 PolarHBondContact O-N 3.13Å; L368-F370 VanDerWaalsContact C-N 3.33Å; L368-F370 PolarHBondContact O-N 2.75Å; L368-F371 HydrophobicContact CD1-CB 4.41Å; L368-F371 WeakPolarHBondContact O-CB 3.31Å; L368-F371 PolarHBondContact O-N 3.11Å; L368-F371 VanDerWaalsContact O-N 3.13Å; L368-I506 HydrophobicContact CB-CG2 4.07Å; L368-I506 HydrophobicContact CD2-CB 4.26Å; L368-I506 HydrophobicContact CD2-CG1 4.32Å; L368-I506 HydrophobicContact CD2-CG2 3.81Å
369	A	92.8	Very high	89	Confident	2 Å²	2	15.9 Å²	15.9	2%	0.017	9%	0.085	C	C	.	.	H	α-helix	trans	-61.3	-40.6	-179.6	0	0	0	0	0	112.4	V365 L366 F371 Y404	V365-A369 PolarHBondContact O-N 3.45Å; L366-A369 PolarHBondContact O-N 3.33Å; A369-F371 VanDerWaalsContact C-N 3.28Å; A369-F371 PolarHBondContact O-N 3.2Å; A369-Y404 HydrophobicContact CB-CE2 3.7Å; A369-Y404 PolarHBondContact O-OH 3.1Å; A369-Y404 VanDerWaalsContact O-OH 3.09Å
370	F	93.3	Very high	88.6	Confident	0 Å²	0	11.9 Å²	11.9	0%	0	7%	0.067	C	C	.	.	T	Hydrogen-bonded Turn	trans	-89.4	16.2	176.8	-70.2	-70.1	0	0	0	113.7	T161 L366 L368 I372 Y397 V400 T401 Y404	T161-F370 HydrophobicContact CG2-CB 3.94Å; T161-F370 WeakPolarHBondContact OG1-CB 3.44Å; L366-F370 HydrophobicContact CB-CD2 4.32Å; L366-F370 HydrophobicContact CB-CE2 4.48Å; L366-F370 HydrophobicContact CD2-CE2 4.08Å; L366-F370 VanDerWaalsContact O-CD2 3.32Å; L366-F370 WeakPolarHBondContact O-CD2 3.37Å; L366-F370 PolarHBondContact O-N 2.87Å; L368-F370 VanDerWaalsContact C-N 3.33Å; L368-F370 PolarHBondContact O-N 2.75Å; F370-I372 PolarHBondContact O-N 3.4Å; F370-Y397 HydrophobicContact CB-CE1 4.24Å; F370-Y397 HydrophobicContact CD1-CD1 4.05Å; F370-Y397 HydrophobicContact CD1-CE1 4.09Å; F370-Y397 PolarHBondContact O-OH 3.23Å; F370-V400 HydrophobicContact CD1-CG1 3.81Å; F370-V400 HydrophobicContact CE1-CB 4.29Å; F370-V400 HydrophobicContact CE1-CG1 3.52Å; F370-T401 WeakPolarHBondContact CE1-OG1 3.23Å; F370-T401 HydrophobicContact CZ-CG2 4.39Å; F370-Y404 HydrophobicContact CD1-CE2 4.3Å; F370-Y404 HydrophobicContact CE1-CD2 4Å; F370-Y404 HydrophobicContact CE1-CE2 4.04Å; F370-Y404 HydrophobicContact CE2-CD2 4.16Å; F370-Y404 HydrophobicContact CE2-CE2 4.43Å; F370-Y404 AromaticContact CZ-CD2 3.7Å; F370-Y404 HydrophobicContact CZ-CD2 3.7Å; F370-Y404 HydrophobicContact CZ-CE2 4.1Å
371	F	89.9	Confident	87.9	Confident	34 Å²	34	14 Å²	14	15%	0.149	8%	0.076	C	C	.	.			trans	-82.3	108.4	-174.7	-170.1	-106.3	0	0	0	112.3	S208 L368 A369 N374 F517 V518	S208-F371 WeakPolarHBondContact OG-CD1 3.49Å; S208-F371 WeakPolarHBondContact OG-CE1 3.42Å; L368-F371 HydrophobicContact CD1-CB 4.41Å; L368-F371 WeakPolarHBondContact O-CB 3.31Å; L368-F371 PolarHBondContact O-N 3.11Å; L368-F371 VanDerWaalsContact O-N 3.13Å; A369-F371 VanDerWaalsContact C-N 3.28Å; A369-F371 PolarHBondContact O-N 3.2Å; F371-N374 HydrophobicContact CE1-CB 4.34Å; F371-N374 HydrophobicContact CZ-CB 4.29Å; F371-N374 WeakPolarHBondContact CZ-ND2 3.18Å; F371-N374 WeakPolarHBondContact CZ-OD1 3.32Å; F371-F517 HydrophobicContact CE2-CB 3.91Å; F371-F517 HydrophobicContact CZ-CB 4.4Å; F371-V518 HydrophobicContact CD2-CG2 4.08Å; F371-V518 HydrophobicContact CE2-CG2 4.39Å
372	I	89.1	Confident	87	Confident	1 Å²	1	16.8 Å²	16.8	1%	0.005	9%	0.091	C	C	.	.			trans	-137.3	-0.6	169.4	-155.7	168.4	0	0	0	112.9	I126 T129 M130 F370 N374 C375 I376 L379 Y397	I126-I372 HydrophobicContact CB-CD1 4.23Å; I126-I372 HydrophobicContact CG1-CD1 4.25Å; I126-I372 HydrophobicContact CG2-CD1 3.77Å; T129-I372 HydrophobicContact CG2-CD1 4.2Å; T129-I372 HydrophobicContact CG2-CG1 4.46Å; M130-I372 HydrophobicContact CE-CB 3.52Å; M130-I372 HydrophobicContact CE-CD1 3.96Å; M130-I372 HydrophobicContact CE-CG1 4.34Å; M130-I372 HydrophobicContact CE-CG2 3.17Å; M130-I372 HydrophobicContact CG-CB 4.45Å; M130-I372 HydrophobicContact CG-CD1 4.4Å; F370-I372 PolarHBondContact O-N 3.4Å; I372-N374 PolarHBondContact O-N 3.33Å; I372-C375 VanDerWaalsContact CG1-SG 3.59Å; I372-C375 PolarHBondContact O-N 2.81Å; I372-I376 HydrophobicContact CD1-CD1 4.36Å; I372-I376 HydrophobicContact CG2-CB 4.19Å; I372-I376 HydrophobicContact CG2-CD1 4.27Å; I372-I376 HydrophobicContact CG2-CG1 4.45Å; I372-I376 WeakPolarHBondContact O-CB 3.39Å; I372-I376 PolarHBondContact O-N 3.38Å; I372-L379 HydrophobicContact CD1-CD1 3.55Å; I372-L379 HydrophobicContact CG1-CD1 3.95Å; I372-Y397 HydrophobicContact CG2-CE2 4.23Å
373	H	88.4	Confident	86.3	Confident	0 Å²	0	16.9 Å²	16.9	0%	0	9%	0.092	C	C	.	.	T	Hydrogen-bonded Turn	trans	-56.2	-29.7	-169.2	-60.2	58.7	0	0	0	112.7	T161 C165 V168 Y397	T161-H373 PolarHBondContact O-NE2 2.69Å; C165-H373 PolarHBondContact N-NE2 3.1Å; V168-H373 HydrophobicContact CG2-CB 4.37Å; H373-Y397 PolarHBondContact CE1-OH 3.02Å
374	N	82.4	Confident	85.6	Confident	18 Å²	18	22.7 Å²	22.7	10%	0.096	12%	0.115	C	C	.	.	T	Hydrogen-bonded Turn	trans	-76.6	-24.4	-177.5	-66.4	17.5	0	0	0	114.1	S205 F371 I372 F517	S205-N374 WeakPolarHBondContact CA-ND2 2.84Å; S205-N374 VanDerWaalsContact CB-ND2 3.31Å; S205-N374 WeakPolarHBondContact CB-ND2 3.31Å; S205-N374 PolarHBondContact OG-ND2 3.32Å; F371-N374 HydrophobicContact CE1-CB 4.34Å; F371-N374 HydrophobicContact CZ-CB 4.29Å; F371-N374 WeakPolarHBondContact CZ-ND2 3.18Å; F371-N374 WeakPolarHBondContact CZ-OD1 3.32Å; I372-N374 PolarHBondContact O-N 3.33Å; N374-F517 WeakPolarHBondContact OD1-CD1 3.25Å; N374-F517 VanDerWaalsContact OD1-CE1 3.31Å; N374-F517 WeakPolarHBondContact OD1-CE1 3.46Å; N374-F517 WeakPolarHBondContact OD1-CG 3.37Å
375	C	79.7	Confident	85.1	Confident	39 Å²	39	28.9 Å²	28.9	26%	0.264	14%	0.142	S	C	.	.	T	Hydrogen-bonded Turn	trans	-122.9	-2	-175.5	62.4	0	0	0	0	113.5	I372 I377 T378 L379	I372-C375 VanDerWaalsContact CG1-SG 3.59Å; I372-C375 PolarHBondContact O-N 2.81Å; C375-I377 PolarHBondContact O-N 3.45Å; C375-T378 PolarHBondContact O-N 3.49Å; C375-L379 WeakPolarHBondContact O-CG 3.48Å; C375-L379 PolarHBondContact O-N 3.14Å
376	I	85.1	Confident	84.5	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-60.5	-34.4	-177	-169.8	57.5	0	0	0	112.8	I126 V168 V169 I372 L379 L380 L393	I126-I376 HydrophobicContact CD1-CD1 3.75Å; I126-I376 HydrophobicContact CG1-CD1 4.06Å; V168-I376 HydrophobicContact CG1-CG2 3.85Å; V169-I376 HydrophobicContact CG2-CG1 3.85Å; V169-I376 HydrophobicContact CG2-CG2 4.03Å; I372-I376 HydrophobicContact CD1-CD1 4.36Å; I372-I376 HydrophobicContact CG2-CB 4.19Å; I372-I376 HydrophobicContact CG2-CD1 4.27Å; I372-I376 HydrophobicContact CG2-CG1 4.45Å; I372-I376 WeakPolarHBondContact O-CB 3.39Å; I372-I376 PolarHBondContact O-N 3.38Å; I376-L379 PolarHBondContact O-N 2.88Å; I376-L380 HydrophobicContact CD1-CD1 3.96Å; I376-L380 HydrophobicContact CD1-CG 3.9Å; I376-L380 HydrophobicContact CG1-CD1 3.74Å; I376-L380 HydrophobicContact CG1-CG 4.14Å; I376-L380 WeakPolarHBondContact O-CB 3.44Å; I376-L380 WeakPolarHBondContact O-CG 3.18Å; I376-L380 PolarHBondContact O-N 3.2Å; I376-L393 HydrophobicContact CD1-CD1 3.73Å; I376-L393 HydrophobicContact CG1-CD1 4.04Å
377	I	82.6	Confident	84	Confident	1 Å²	1	41.4 Å²	41.4	1%	0.005	20%	0.201	C	C	.	.	H	α-helix	trans	-62.4	-51.2	177.2	-75.1	176.2	0	0	0	110.5	V168 R172 W183 Y185 C375 L379 L380 K381	V168-I377 HydrophobicContact CG1-CD1 4.3Å; V168-I377 HydrophobicContact CG1-CG1 4.48Å; R172-I377 HydrophobicContact CG-CD1 3.97Å; W183-I377 WeakPolarHBondContact O-CG2 3.23Å; Y185-I377 HydrophobicContact CD2-CD1 4.15Å; Y185-I377 HydrophobicContact CG-CD1 4.45Å; C375-I377 PolarHBondContact O-N 3.45Å; I377-L379 VanDerWaalsContact C-N 3.33Å; I377-L379 PolarHBondContact O-N 2.83Å; I377-L380 PolarHBondContact O-N 3.45Å; I377-K381 WeakPolarHBondContact O-CB 3.28Å; I377-K381 PolarHBondContact O-N 3.27Å
378	T	78.4	Confident	83.7	Confident	58 Å²	58	43.3 Å²	43.3	36%	0.356	21%	0.211	S	C	.	.	H	α-helix	trans	-59.1	-43.4	175.3	-35.6	0	0	0	0	111.9	E184 C375 K381 N382	E184-T378 WeakPolarHBondContact OE1-CB 3.45Å; E184-T378 PolarHBondContact OE1-OG1 3.49Å; E184-T378 PolarHBondContact OE2-OG1 3.29Å; C375-T378 PolarHBondContact O-N 3.49Å; T378-K381 PolarHBondContact O-N 3.38Å; T378-N382 PolarHBondContact O-ND2 2.94Å
379	L	76.9	Confident	83.6	Confident	25 Å²	25	42.6 Å²	42.6	13%	0.131	21%	0.207	C	C	.	.	H	α-helix	trans	-65.7	-44.1	-177.8	-69.9	172.6	0	0	0	111.8	M125 I372 C375 I376 I377 N382	M125-L379 HydrophobicContact CE-CB 3.81Å; M125-L379 HydrophobicContact CE-CD2 3.44Å; M125-L379 VanDerWaalsContact CE-CD2 3.44Å; M125-L379 HydrophobicContact CE-CG 4.17Å; M125-L379 HydrophobicContact CG-CD2 4.17Å; M125-L379 HydrophobicContact SD-CD2 3.74Å; I372-L379 HydrophobicContact CD1-CD1 3.55Å; I372-L379 HydrophobicContact CG1-CD1 3.95Å; C375-L379 WeakPolarHBondContact O-CG 3.48Å; C375-L379 PolarHBondContact O-N 3.14Å; I376-L379 PolarHBondContact O-N 2.88Å; I377-L379 VanDerWaalsContact C-N 3.33Å; I377-L379 PolarHBondContact O-N 2.83Å; L379-N382 PolarHBondContact O-N 3.4Å
380	L	81.6	Confident	83.5	Confident	0 Å²	0	45.9 Å²	45.9	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-73.2	-28.7	179.5	-70.1	174.3	0	0	0	112.7	T122 I126 V169 I376 I377 N382 N383 Q386 N389	T122-L380 HydrophobicContact CG2-CD2 3.96Å; I126-L380 HydrophobicContact CD1-CD2 4.04Å; V169-L380 HydrophobicContact CB-CD1 4.37Å; V169-L380 HydrophobicContact CG1-CD1 3.85Å; V169-L380 HydrophobicContact CG2-CD1 3.52Å; I376-L380 HydrophobicContact CD1-CD1 3.96Å; I376-L380 HydrophobicContact CD1-CG 3.9Å; I376-L380 HydrophobicContact CG1-CD1 3.74Å; I376-L380 HydrophobicContact CG1-CG 4.14Å; I376-L380 WeakPolarHBondContact O-CB 3.44Å; I376-L380 WeakPolarHBondContact O-CG 3.18Å; I376-L380 PolarHBondContact O-N 3.2Å; I377-L380 PolarHBondContact O-N 3.45Å; L380-N382 PolarHBondContact O-N 3.29Å; L380-N383 VanDerWaalsContact O-CB 3.25Å; L380-N383 WeakPolarHBondContact O-CB 3.29Å; L380-N383 PolarHBondContact O-N 2.94Å; L380-Q386 PolarHBondContact O-NE2 3.24Å; L380-Q386 PolarHBondContact O-OE1 2.93Å; L380-N389 HydrophobicContact CD1-CB 4.26Å; L380-N389 HydrophobicContact CD2-CB 4.12Å
381	K	77.9	Confident	83.5	Confident	53 Å²	53	51.4 Å²	51.4	23%	0.23	25%	0.248	C	C	.	.	H	α-helix	trans	-58	-28.8	174.3	-173.4	173.9	176.5	176.6	0	112.2	E112 T181 I377 T378 N383 Q386	E112-K381 WeakPolarHBondContact O-CE 3.41Å; E112-K381 IonicContact OE2-NZ 3.79Å; T181-K381 WeakPolarHBondContact O-CE 3.19Å; T181-K381 PolarHBondContact O-NZ 2.61Å; I377-K381 WeakPolarHBondContact O-CB 3.28Å; I377-K381 PolarHBondContact O-N 3.27Å; T378-K381 PolarHBondContact O-N 3.38Å; K381-N383 VanDerWaalsContact C-N 3.27Å; K381-N383 PolarHBondContact O-N 3.11Å; K381-Q386 PolarHBondContact O-NE2 2.72Å
382	N	74.8	Confident	83.7	Confident	74 Å²	74	49.8 Å²	49.8	40%	0.396	24%	0.241	S	C	.	.	T	Hydrogen-bonded Turn	trans	-77.6	-5.8	178	-67.7	-39.8	0	0	0	114.5	G115 K116 N117 T378 L379 L380	G115-N382 CarbonylContact C-O 3.32Å; G115-N382 VanDerWaalsContact CA-C 3.42Å; G115-N382 WeakPolarHBondContact CA-O 3.35Å; K116-N382 PolarHBondContact N-O 3.31Å; N117-N382 WeakPolarHBondContact CB-O 3.18Å; N117-N382 PolarHBondContact N-O 2.78Å; T378-N382 PolarHBondContact O-ND2 2.94Å; L379-N382 PolarHBondContact O-N 3.4Å; L380-N382 PolarHBondContact O-N 3.29Å
383	N	79.9	Confident	83.9	Confident	1 Å²	1	49.8 Å²	49.8	1%	0.005	24%	0.241	C	C	.	.	B	Isolated β-bridge	trans	-77.2	133.4	179.7	-167.9	7.6	0	0	0	112	N117 T122 L380 K381 K385 Q386 N389 D392	N117-N383 PolarHBondContact O-OD1 3.11Å; T122-N383 HydrophobicContact CG2-CB 4.32Å; L380-N383 VanDerWaalsContact O-CB 3.25Å; L380-N383 WeakPolarHBondContact O-CB 3.29Å; L380-N383 PolarHBondContact O-N 2.94Å; K381-N383 VanDerWaalsContact C-N 3.27Å; K381-N383 PolarHBondContact O-N 3.11Å; N383-K385 VanDerWaalsContact C-N 3.31Å; N383-K385 PolarHBondContact ND2-O 3.34Å; N383-K385 PolarHBondContact O-N 2.87Å; N383-Q386 PolarHBondContact O-NE2 2.96Å; N383-N389 PolarHBondContact ND2-OD1 2.87Å; N383-D392 PolarHBondContact ND2-OD2 3Å
384	K	79.2	Confident	84.2	Confident	143 Å²	143	52.4 Å²	52.4	62%	0.622	26%	0.258	S	S	*	.	S	Bend	trans	-64.4	-35.1	-179.5	-171.5	175	179.8	177.8	0	112.8	G115 N117	G115-K384 WeakPolarHBondContact O-CA 3.12Å; G115-K384 VanDerWaalsContact O-CB 3.22Å; G115-K384 WeakPolarHBondContact O-CB 3.21Å; N117-K384 WeakPolarHBondContact O-CB 3.31Å; N117-K384 PolarHBondContact O-N 2.87Å
385	K	82.4	Confident	84.9	Confident	130 Å²	130	55.2 Å²	55.2	57%	0.565	27%	0.272	S	S	*	.			trans	-114.9	86.7	-177.6	-66.9	-172.4	179.1	-172.9	0	110.8	N383 E387 N388	N383-K385 VanDerWaalsContact C-N 3.31Å; N383-K385 PolarHBondContact ND2-O 3.34Å; N383-K385 PolarHBondContact O-N 2.87Å; K385-E387 PolarHBondContact O-N 3.34Å; K385-N388 PolarHBondContact O-N 3.41Å; K385-N388 VanDerWaalsContact O-N 3.13Å
386	Q	81.8	Confident	85.6	Confident	77 Å²	77	53.3 Å²	53.3	36%	0.36	26%	0.26	S	S	.	.	G	3₁₀ helix	trans	-60.1	-28.5	-175.7	-66.3	-66	-46.8	0	0	113.9	L380 K381 N383 N388 N389	L380-Q386 PolarHBondContact O-NE2 3.24Å; L380-Q386 PolarHBondContact O-OE1 2.93Å; K381-Q386 PolarHBondContact O-NE2 2.72Å; N383-Q386 PolarHBondContact O-NE2 2.96Å; Q386-N388 PolarHBondContact O-N 2.93Å; Q386-N389 VanDerWaalsContact O-CB 3.26Å; Q386-N389 WeakPolarHBondContact O-CB 3.34Å; Q386-N389 PolarHBondContact O-N 3.02Å; Q386-N389 VanDerWaalsContact O-N 3.15Å; Q386-N389 PolarHBondContact O-ND2 2.85Å; Q386-N389 PolarHBondContact OE1-ND2 2.88Å
387	E	82.9	Confident	86.1	Confident	185 Å²	185	53.4 Å²	53.4	86%	0.864	26%	0.26	S	S	*	.	G	3₁₀ helix	trans	-60.2	-31.5	177.1	-63	173.4	-178.9	0	0	113	K385 N389	K385-E387 PolarHBondContact O-N 3.34Å; E387-N389 VanDerWaalsContact C-N 3.3Å; E387-N389 PolarHBondContact O-N 3.45Å
388	N	88.1	Confident	86.7	Confident	41 Å²	41	57.8 Å²	57.8	22%	0.219	28%	0.282	C	S	.	.	G	3₁₀ helix	trans	-85.4	-0.9	-178.3	-70.6	-44.4	0	0	0	113.5	K385 Q386 V390 R391 D392	K385-N388 PolarHBondContact O-N 3.41Å; K385-N388 VanDerWaalsContact O-N 3.13Å; Q386-N388 PolarHBondContact O-N 2.93Å; N388-V390 VanDerWaalsContact C-N 3.27Å; N388-V390 PolarHBondContact O-N 3.18Å; N388-R391 WeakPolarHBondContact O-CB 2.89Å; N388-R391 PolarHBondContact O-N 3.14Å; N388-R391 PolarHBondContact OD1-NH1 3.08Å; N388-D392 WeakPolarHBondContact O-CB 3.31Å; N388-D392 VanDerWaalsContact O-CG 3.23Å; N388-D392 PolarHBondContact O-N 3.2Å
389	N	88.6	Confident	87.5	Confident	12 Å²	12	57.7 Å²	57.7	6%	0.064	28%	0.279	C	S	.	.	H	α-helix	trans	-55.5	-39.8	-173.3	-77.2	-10.8	0	0	0	113.4	L380 N383 Q386 E387 D392 L393	L380-N389 HydrophobicContact CD1-CB 4.26Å; L380-N389 HydrophobicContact CD2-CB 4.12Å; N383-N389 PolarHBondContact ND2-OD1 2.87Å; Q386-N389 VanDerWaalsContact O-CB 3.26Å; Q386-N389 WeakPolarHBondContact O-CB 3.34Å; Q386-N389 PolarHBondContact O-N 3.02Å; Q386-N389 VanDerWaalsContact O-N 3.15Å; Q386-N389 PolarHBondContact O-ND2 2.85Å; Q386-N389 PolarHBondContact OE1-ND2 2.88Å; E387-N389 VanDerWaalsContact C-N 3.3Å; E387-N389 PolarHBondContact O-N 3.45Å; N389-D392 PolarHBondContact O-N 2.93Å; N389-L393 VanDerWaalsContact O-CB 3.24Å; N389-L393 WeakPolarHBondContact O-CB 3.26Å; N389-L393 PolarHBondContact O-N 2.92Å
390	V	90.9	Very high	88.4	Confident	71 Å²	71	56.5 Å²	56.5	43%	0.43	27%	0.272	S	S	.	.	H	α-helix	trans	-67	-41	179.3	177	0	0	0	0	111.1	Y166 N388 C394	Y166-V390 HydrophobicContact CD2-CG1 3.75Å; Y166-V390 HydrophobicContact CD2-CG2 4.12Å; Y166-V390 HydrophobicContact CE2-CG1 3.73Å; Y166-V390 HydrophobicContact CE2-CG2 3.89Å; N388-V390 VanDerWaalsContact C-N 3.27Å; N388-V390 PolarHBondContact O-N 3.18Å; V390-C394 WeakPolarHBondContact O-CB 3.44Å; V390-C394 PolarHBondContact O-N 3.41Å
391	R	93.4	Very high	89.1	Confident	117 Å²	117	57.1 Å²	57.1	44%	0.442	28%	0.276	S	S	.	.	H	α-helix	trans	-64.4	-48.9	175.5	-179.3	-159.9	67.5	-163.3	-0.8	110.4	S119 N388 L393 C394 I395	S119-R391 PolarHBondContact OG-NH2 3.12Å; N388-R391 WeakPolarHBondContact O-CB 2.89Å; N388-R391 PolarHBondContact O-N 3.14Å; N388-R391 PolarHBondContact OD1-NH1 3.08Å; R391-L393 VanDerWaalsContact C-N 3.3Å; R391-L393 PolarHBondContact O-N 2.62Å; R391-C394 PolarHBondContact O-N 2.88Å; R391-I395 HydrophobicContact CG-CD1 3.86Å; R391-I395 WeakPolarHBondContact O-CG1 3.19Å; R391-I395 PolarHBondContact O-N 3.15Å
392	D	93.5	Very high	89.9	Confident	0 Å²	0	59.5 Å²	59.5	0%	0	29%	0.291	C	S	.	.	H	α-helix	trans	-61.8	-40.1	-178.3	-63.6	-11.6	0	0	0	110.4	S119 I123 N383 N388 N389 A396	S119-D392 WeakPolarHBondContact CA-OD2 3.16Å; S119-D392 WeakPolarHBondContact CB-OD2 3.2Å; S119-D392 PolarHBondContact OG-OD2 3.16Å; I123-D392 HydrophobicContact CD1-CB 4.29Å; I123-D392 HydrophobicContact CG1-CB 3.83Å; N383-D392 PolarHBondContact ND2-OD2 3Å; N388-D392 WeakPolarHBondContact O-CB 3.31Å; N388-D392 VanDerWaalsContact O-CG 3.23Å; N388-D392 PolarHBondContact O-N 3.2Å; N389-D392 PolarHBondContact O-N 2.93Å; D392-A396 WeakPolarHBondContact O-CB 3.36Å; D392-A396 PolarHBondContact O-N 3.37Å
393	L	93.8	Very high	90.9	Very high	1 Å²	1	56.7 Å²	56.7	1%	0.005	28%	0.277	C	S	.	.	H	α-helix	trans	-60.7	-48.3	172.4	-177.4	67.7	0	0	0	112.5	I126 L162 C165 V169 I376 N389 R391 A396 Y397	I126-L393 HydrophobicContact CD1-CD1 4.45Å; L162-L393 HydrophobicContact CD1-CD2 4.38Å; L162-L393 HydrophobicContact CD1-CG 4.08Å; C165-L393 HydrophobicContact CB-CD2 4.38Å; V169-L393 HydrophobicContact CG2-CD2 4.16Å; I376-L393 HydrophobicContact CD1-CD1 3.73Å; I376-L393 HydrophobicContact CG1-CD1 4.04Å; N389-L393 VanDerWaalsContact O-CB 3.24Å; N389-L393 WeakPolarHBondContact O-CB 3.26Å; N389-L393 PolarHBondContact O-N 2.92Å; R391-L393 VanDerWaalsContact C-N 3.3Å; R391-L393 PolarHBondContact O-N 2.62Å; L393-A396 PolarHBondContact O-N 3.47Å; L393-Y397 HydrophobicContact CD1-CD2 3.8Å; L393-Y397 HydrophobicContact CD1-CE2 3.61Å; L393-Y397 HydrophobicContact CG-CD2 4.14Å; L393-Y397 HydrophobicContact CG-CE2 4.26Å; L393-Y397 WeakPolarHBondContact O-CD2 3.09Å; L393-Y397 PolarHBondContact O-N 3.43Å
394	C	95.4	Very high	91.6	Very high	54 Å²	54	56.7 Å²	56.7	37%	0.365	28%	0.276	S	S	.	.	H	α-helix	trans	-61.2	-46.8	180	-175.7	0	0	0	0	111.5	V390 R391 A396 Y397 M398	V390-C394 WeakPolarHBondContact O-CB 3.44Å; V390-C394 PolarHBondContact O-N 3.41Å; R391-C394 PolarHBondContact O-N 2.88Å; C394-A396 VanDerWaalsContact C-N 3.31Å; C394-A396 PolarHBondContact O-N 3.49Å; C394-Y397 PolarHBondContact O-N 2.93Å; C394-M398 WeakPolarHBondContact O-CB 3.43Å; C394-M398 VanDerWaalsContact O-CG 3.3Å; C394-M398 WeakPolarHBondContact O-CG 3.33Å; C394-M398 PolarHBondContact O-N 3.46Å
395	I	95.8	Very high	92.4	Very high	77 Å²	77	50.9 Å²	50.9	40%	0.395	25%	0.252	S	S	.	.	H	α-helix	trans	-60.8	-42.3	177.2	-65.1	168.5	0	0	0	110.6	I123 R391 M398 L399	I123-I395 HydrophobicContact CD1-CB 4.23Å; I123-I395 HydrophobicContact CD1-CD1 4.23Å; I123-I395 HydrophobicContact CD1-CG2 4.07Å; I123-I395 HydrophobicContact CG2-CG2 4Å; R391-I395 HydrophobicContact CG-CD1 3.86Å; R391-I395 WeakPolarHBondContact O-CG1 3.19Å; R391-I395 PolarHBondContact O-N 3.15Å; I395-M398 PolarHBondContact O-N 3.2Å; I395-L399 WeakPolarHBondContact O-CB 3.29Å; I395-L399 PolarHBondContact O-N 2.95Å
396	A	94.5	Very high	93.1	Very high	0 Å²	0	49.4 Å²	49.4	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-63.1	-47.7	178.8	0	0	0	0	0	112.2	I123 I126 D392 L393 C394 M398 L399 V400	I123-A396 HydrophobicContact CG2-CB 4.13Å; I126-A396 HydrophobicContact CB-CB 3.82Å; I126-A396 HydrophobicContact CD1-CB 4.41Å; I126-A396 HydrophobicContact CG2-CB 3.49Å; I126-A396 VanDerWaalsContact CG2-CB 3.49Å; D392-A396 WeakPolarHBondContact O-CB 3.36Å; D392-A396 PolarHBondContact O-N 3.37Å; L393-A396 PolarHBondContact O-N 3.47Å; C394-A396 VanDerWaalsContact C-N 3.31Å; C394-A396 PolarHBondContact O-N 3.49Å; A396-M398 VanDerWaalsContact C-N 3.34Å; A396-M398 PolarHBondContact O-N 3.15Å; A396-L399 PolarHBondContact O-N 3.14Å; A396-V400 VanDerWaalsContact O-CG2 3.28Å; A396-V400 WeakPolarHBondContact O-CG2 3.46Å; A396-V400 PolarHBondContact O-N 3.1Å
397	Y	95.4	Very high	93.7	Very high	1 Å²	1	45.8 Å²	45.8	0%	0.004	23%	0.227	C	C	.	.	H	α-helix	trans	-63.4	-38.4	176.7	-93.9	-97.7	0	0	0	112.9	M130 L162 C165 F370 I372 H373 L393 C394 V400 T401	M130-Y397 HydrophobicContact CE-CD2 4.01Å; M130-Y397 HydrophobicContact CE-CE1 4.06Å; M130-Y397 HydrophobicContact CE-CE2 3.41Å; M130-Y397 VanDerWaalsContact CE-CE2 3.41Å; M130-Y397 VanDerWaalsContact CE-CZ 3.44Å; L162-Y397 HydrophobicContact CB-CD1 3.74Å; L162-Y397 HydrophobicContact CB-CE1 4.25Å; L162-Y397 HydrophobicContact CB-CG 3.89Å; L162-Y397 HydrophobicContact CD1-CD1 4.48Å; L162-Y397 HydrophobicContact CD1-CD2 3.76Å; L162-Y397 HydrophobicContact CD1-CE2 4.41Å; L162-Y397 HydrophobicContact CD1-CG 3.79Å; L162-Y397 HydrophobicContact CG-CG 4.32Å; C165-Y397 HydrophobicContact CB-CE2 3.91Å; C165-Y397 VanDerWaalsContact CB-OH 3.27Å; C165-Y397 WeakPolarHBondContact CB-OH 2.99Å; C165-Y397 PolarHBondContact SG-OH 3.29Å; C165-Y397 VanDerWaalsContact SG-OH 3.41Å; F370-Y397 HydrophobicContact CB-CE1 4.24Å; F370-Y397 HydrophobicContact CD1-CD1 4.05Å; F370-Y397 HydrophobicContact CD1-CE1 4.09Å; F370-Y397 PolarHBondContact O-OH 3.23Å; I372-Y397 HydrophobicContact CG2-CE2 4.23Å; H373-Y397 PolarHBondContact CE1-OH 3.02Å; L393-Y397 HydrophobicContact CD1-CD2 3.8Å; L393-Y397 HydrophobicContact CD1-CE2 3.61Å; L393-Y397 HydrophobicContact CG-CD2 4.14Å; L393-Y397 HydrophobicContact CG-CE2 4.26Å; L393-Y397 WeakPolarHBondContact O-CD2 3.09Å; L393-Y397 PolarHBondContact O-N 3.43Å; C394-Y397 PolarHBondContact O-N 2.93Å; Y397-V400 PolarHBondContact O-N 3.5Å; Y397-T401 WeakPolarHBondContact O-CB 3.43Å; Y397-T401 PolarHBondContact O-N 2.96Å; Y397-T401 PolarHBondContact O-OG1 3.44Å
398	M	96.1	Very high	94.3	Very high	93 Å²	93	37 Å²	37	46%	0.458	19%	0.186	S	C	.	.	H	α-helix	trans	-61.9	-46	173.9	-74.7	-61.9	-62.5	0	0	110.9	C394 I395 A396 V400 T401 L402	C394-M398 WeakPolarHBondContact O-CB 3.43Å; C394-M398 VanDerWaalsContact O-CG 3.3Å; C394-M398 WeakPolarHBondContact O-CG 3.33Å; C394-M398 PolarHBondContact O-N 3.46Å; I395-M398 PolarHBondContact O-N 3.2Å; A396-M398 VanDerWaalsContact C-N 3.34Å; A396-M398 PolarHBondContact O-N 3.15Å; M398-V400 VanDerWaalsContact C-N 3.35Å; M398-V400 PolarHBondContact O-N 3.43Å; M398-T401 PolarHBondContact O-N 3.22Å; M398-L402 WeakPolarHBondContact O-CB 3.19Å; M398-L402 VanDerWaalsContact O-CG 3.24Å; M398-L402 WeakPolarHBondContact O-CG 3.34Å; M398-L402 PolarHBondContact O-N 3.01Å
399	L	94.8	Very high	94.7	Very high	56 Å²	56	36.8 Å²	36.8	29%	0.293	19%	0.186	S	C	.	.	H	α-helix	trans	-60.9	-43.9	176.5	-173.6	65.5	0	0	0	111.4	W127 I395 A396 L402 T403	W127-L399 HydrophobicContact CB-CD2 4.13Å; W127-L399 VanDerWaalsContact CD1-CG 3.49Å; W127-L399 HydrophobicContact CD2-CD2 4.17Å; W127-L399 HydrophobicContact CG-CD2 3.68Å; W127-L399 HydrophobicContact CG-CG 4.16Å; I395-L399 WeakPolarHBondContact O-CB 3.29Å; I395-L399 PolarHBondContact O-N 2.95Å; A396-L399 PolarHBondContact O-N 3.14Å; L399-L402 PolarHBondContact O-N 3.02Å; L399-T403 WeakPolarHBondContact O-CG2 3.48Å; L399-T403 PolarHBondContact O-N 2.94Å; L399-T403 PolarHBondContact O-OG1 3.19Å
400	V	95.3	Very high	95	Very high	0 Å²	0	37.3 Å²	37.3	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-61.6	-48.9	177.4	170.3	0	0	0	0	111.5	W127 M130 M131 F370 A396 Y397 M398 L402 T403 Y404	W127-V400 HydrophobicContact CB-CG2 4.31Å; W127-V400 HydrophobicContact CG-CG2 4.25Å; M130-V400 HydrophobicContact CB-CG1 4.16Å; M130-V400 HydrophobicContact CB-CG2 4.01Å; M130-V400 HydrophobicContact CG-CG2 4.46Å; M130-V400 HydrophobicContact SD-CB 4.22Å; M130-V400 HydrophobicContact SD-CG1 3.93Å; M130-V400 HydrophobicContact SD-CG2 3.72Å; M131-V400 HydrophobicContact CE-CB 3.81Å; M131-V400 HydrophobicContact CE-CG1 3.57Å; M131-V400 HydrophobicContact CE-CG2 3.75Å; F370-V400 HydrophobicContact CD1-CG1 3.81Å; F370-V400 HydrophobicContact CE1-CB 4.29Å; F370-V400 HydrophobicContact CE1-CG1 3.52Å; A396-V400 VanDerWaalsContact O-CG2 3.28Å; A396-V400 WeakPolarHBondContact O-CG2 3.46Å; A396-V400 PolarHBondContact O-N 3.1Å; Y397-V400 PolarHBondContact O-N 3.5Å; M398-V400 VanDerWaalsContact C-N 3.35Å; M398-V400 PolarHBondContact O-N 3.43Å; V400-L402 VanDerWaalsContact C-N 3.33Å; V400-L402 PolarHBondContact O-N 3.41Å; V400-T403 WeakPolarHBondContact CA-OG1 3.47Å; V400-T403 PolarHBondContact O-N 2.95Å; V400-T403 PolarHBondContact O-OG1 2.94Å; V400-Y404 HydrophobicContact CG1-CD2 3.9Å; V400-Y404 HydrophobicContact CG1-CE1 4.43Å; V400-Y404 HydrophobicContact CG1-CE2 3.42Å; V400-Y404 VanDerWaalsContact CG1-CE2 3.42Å; V400-Y404 PolarHBondContact O-N 3.41Å
401	T	96.1	Very high	95.2	Very high	14 Å²	14	34.6 Å²	34.6	9%	0.086	17%	0.172	C	C	.	.	H	α-helix	trans	-60	-45.2	179	-54.5	0	0	0	0	110.7	I154 F370 Y397 M398 T403 Y404 L405	I154-T401 HydrophobicContact CG2-CG2 4.27Å; F370-T401 WeakPolarHBondContact CE1-OG1 3.23Å; F370-T401 HydrophobicContact CZ-CG2 4.39Å; Y397-T401 WeakPolarHBondContact O-CB 3.43Å; Y397-T401 PolarHBondContact O-N 2.96Å; Y397-T401 PolarHBondContact O-OG1 3.44Å; M398-T401 PolarHBondContact O-N 3.22Å; T401-T403 PolarHBondContact O-N 3.43Å; T401-Y404 PolarHBondContact O-N 3.27Å; T401-L405 HydrophobicContact CG2-CD1 3.99Å; T401-L405 HydrophobicContact CG2-CG 4.43Å; T401-L405 WeakPolarHBondContact O-CB 3.29Å; T401-L405 VanDerWaalsContact O-CG 3.26Å; T401-L405 WeakPolarHBondContact O-CG 3.31Å; T401-L405 PolarHBondContact O-N 2.98Å
402	L	95.8	Very high	95.3	Very high	102 Å²	102	29.2 Å²	29.2	53%	0.534	15%	0.152	S	C	.	.	H	α-helix	trans	-61.7	-41.9	176.6	-72.8	171.7	0	0	0	112.2	M398 L399 V400 L405 Y406	M398-L402 WeakPolarHBondContact O-CB 3.19Å; M398-L402 VanDerWaalsContact O-CG 3.24Å; M398-L402 WeakPolarHBondContact O-CG 3.34Å; M398-L402 PolarHBondContact O-N 3.01Å; L399-L402 PolarHBondContact O-N 3.02Å; V400-L402 VanDerWaalsContact C-N 3.33Å; V400-L402 PolarHBondContact O-N 3.41Å; L402-L405 PolarHBondContact O-N 3.4Å; L402-Y406 VanDerWaalsContact O-CB 3.22Å; L402-Y406 WeakPolarHBondContact O-CB 3.48Å; L402-Y406 PolarHBondContact O-N 3Å
403	T	95.1	Very high	95.2	Very high	16 Å²	16	29.3 Å²	29.3	10%	0.098	15%	0.153	C	C	.	.	H	α-helix	trans	-67.1	-38.3	177.5	43.1	0	0	0	0	113.2	W127 M131 L399 V400 T401 Y406 I407	W127-T403 HydrophobicContact CZ2-CG2 4.15Å; M131-T403 WeakPolarHBondContact CE-OG1 3.41Å; L399-T403 WeakPolarHBondContact O-CG2 3.48Å; L399-T403 PolarHBondContact O-N 2.94Å; L399-T403 PolarHBondContact O-OG1 3.19Å; V400-T403 WeakPolarHBondContact CA-OG1 3.47Å; V400-T403 PolarHBondContact O-N 2.95Å; V400-T403 PolarHBondContact O-OG1 2.94Å; T401-T403 PolarHBondContact O-N 3.43Å; T403-Y406 PolarHBondContact O-N 2.83Å; T403-I407 PolarHBondContact O-N 3.39Å; T403-I407 VanDerWaalsContact O-N 3.08Å
404	Y	95.7	Very high	95.2	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-67.9	-42.4	174.9	-68.3	-18.3	0	0	0	112.1	M130 M131 S134 I135 I138 A369 F370 V400 T401 G408	M130-Y404 PolarHBondContact O-OH 3.01Å; M131-Y404 HydrophobicContact CE-CD1 3.91Å; M131-Y404 HydrophobicContact CE-CE1 3.46Å; M131-Y404 VanDerWaalsContact CE-CE1 3.46Å; M131-Y404 HydrophobicContact SD-CD1 4.41Å; M131-Y404 HydrophobicContact SD-CE1 3.93Å; S134-Y404 PolarHBondContact OG-OH 3.45Å; I135-Y404 HydrophobicContact CB-CE1 4.22Å; I135-Y404 HydrophobicContact CD1-CD1 4.32Å; I135-Y404 HydrophobicContact CD1-CE1 4.36Å; I135-Y404 HydrophobicContact CG1-CD1 3.98Å; I135-Y404 HydrophobicContact CG1-CE1 4.13Å; I138-Y404 HydrophobicContact CD1-CG 4.4Å; I138-Y404 HydrophobicContact CG1-CD1 4.33Å; I138-Y404 HydrophobicContact CG1-CG 4.32Å; A369-Y404 HydrophobicContact CB-CE2 3.7Å; A369-Y404 PolarHBondContact O-OH 3.1Å; A369-Y404 VanDerWaalsContact O-OH 3.09Å; F370-Y404 HydrophobicContact CD1-CE2 4.3Å; F370-Y404 HydrophobicContact CE1-CD2 4Å; F370-Y404 HydrophobicContact CE1-CE2 4.04Å; F370-Y404 HydrophobicContact CE2-CD2 4.16Å; F370-Y404 HydrophobicContact CE2-CE2 4.43Å; F370-Y404 AromaticContact CZ-CD2 3.7Å; F370-Y404 HydrophobicContact CZ-CD2 3.7Å; F370-Y404 HydrophobicContact CZ-CE2 4.1Å; V400-Y404 HydrophobicContact CG1-CD2 3.9Å; V400-Y404 HydrophobicContact CG1-CE1 4.43Å; V400-Y404 HydrophobicContact CG1-CE2 3.42Å; V400-Y404 VanDerWaalsContact CG1-CE2 3.42Å; V400-Y404 PolarHBondContact O-N 3.41Å; T401-Y404 PolarHBondContact O-N 3.27Å; Y404-G408 WeakPolarHBondContact O-CA 3.29Å; Y404-G408 PolarHBondContact O-N 3.45Å
405	L	96.1	Very high	95	Very high	22 Å²	22	27.5 Å²	27.5	12%	0.115	14%	0.139	C	C	.	.	H	α-helix	trans	-61.3	-45.5	173	-70.8	170.3	0	0	0	110.9	M151 I154 I155 T401 L402 G408 V409	M151-L405 HydrophobicContact CE-CB 4.46Å; M151-L405 HydrophobicContact CE-CD2 3.54Å; M151-L405 HydrophobicContact CE-CG 4.47Å; M151-L405 HydrophobicContact SD-CD2 3.57Å; M151-L405 VanDerWaalsContact SD-CD2 3.57Å; I154-L405 HydrophobicContact CB-CD2 3.71Å; I154-L405 HydrophobicContact CB-CG 4.5Å; I154-L405 HydrophobicContact CD1-CD2 4.05Å; I154-L405 HydrophobicContact CG1-CD2 4.49Å; I154-L405 HydrophobicContact CG2-CD2 3.47Å; I154-L405 VanDerWaalsContact CG2-CD2 3.47Å; I154-L405 HydrophobicContact CG2-CG 3.72Å; I155-L405 HydrophobicContact CD1-CD1 4.41Å; I155-L405 HydrophobicContact CG1-CD1 3.89Å; I155-L405 HydrophobicContact CG1-CD2 4.32Å; T401-L405 HydrophobicContact CG2-CD1 3.99Å; T401-L405 HydrophobicContact CG2-CG 4.43Å; T401-L405 WeakPolarHBondContact O-CB 3.29Å; T401-L405 VanDerWaalsContact O-CG 3.26Å; T401-L405 WeakPolarHBondContact O-CG 3.31Å; T401-L405 PolarHBondContact O-N 2.98Å; L402-L405 PolarHBondContact O-N 3.4Å; L405-G408 PolarHBondContact O-N 3.28Å; L405-V409 VanDerWaalsContact O-CB 3.29Å; L405-V409 WeakPolarHBondContact O-CB 3.38Å; L405-V409 WeakPolarHBondContact O-CG2 3.29Å; L405-V409 PolarHBondContact O-N 3.04Å
406	Y	95.9	Very high	94.7	Very high	99 Å²	99	24.2 Å²	24.2	39%	0.388	12%	0.123	S	C	.	.	H	α-helix	trans	-58.3	-53.1	-179.2	-177.2	-101.1	0	0	0	112	I326 T330 L402 T403 L410	I326-Y406 HydrophobicContact CG2-CD1 4.43Å; I326-Y406 HydrophobicContact CG2-CE1 3.91Å; T330-Y406 PolarHBondContact OG1-OH 2.87Å; L402-Y406 VanDerWaalsContact O-CB 3.22Å; L402-Y406 WeakPolarHBondContact O-CB 3.48Å; L402-Y406 PolarHBondContact O-N 3Å; T403-Y406 PolarHBondContact O-N 2.83Å; Y406-L410 HydrophobicContact CD1-CD1 4.02Å; Y406-L410 HydrophobicContact CD2-CD1 4.2Å; Y406-L410 HydrophobicContact CE1-CD1 3.44Å; Y406-L410 VanDerWaalsContact CE1-CD1 3.44Å; Y406-L410 HydrophobicContact CE2-CD1 3.66Å; Y406-L410 HydrophobicContact CE2-CG 4.39Å; Y406-L410 HydrophobicContact CG-CD1 4.37Å; Y406-L410 WeakPolarHBondContact O-CB 3.13Å; Y406-L410 VanDerWaalsContact O-CG 3.31Å; Y406-L410 WeakPolarHBondContact O-CG 3.47Å; Y406-L410 PolarHBondContact O-N 3.4Å; Y406-L410 WeakPolarHBondContact OH-CD1 3.13Å
407	I	95.6	Very high	94.2	Very high	1 Å²	1	24.3 Å²	24.3	1%	0.005	12%	0.124	C	C	.	.	H	α-helix	trans	-68.9	-43.3	179.7	-74.1	164.9	0	0	0	111.2	I135 I326 V329 T403 V409 L410 V411 F429	I135-I407 HydrophobicContact CD1-CD1 3.21Å; I135-I407 HydrophobicContact CG1-CB 4.47Å; I135-I407 HydrophobicContact CG1-CD1 3.6Å; I135-I407 HydrophobicContact CG1-CG2 4.36Å; I326-I407 HydrophobicContact CG1-CD1 3.96Å; V329-I407 HydrophobicContact CG2-CG2 4.38Å; T403-I407 PolarHBondContact O-N 3.39Å; T403-I407 VanDerWaalsContact O-N 3.08Å; I407-V409 PolarHBondContact O-N 3.08Å; I407-L410 PolarHBondContact O-N 3.33Å; I407-V411 HydrophobicContact CG2-CG2 4.17Å; I407-V411 WeakPolarHBondContact O-CB 3.37Å; I407-V411 VanDerWaalsContact O-CG2 3.29Å; I407-V411 WeakPolarHBondContact O-CG2 3.32Å; I407-V411 PolarHBondContact O-N 2.88Å; I407-F429 HydrophobicContact CG2-CE1 4.16Å
408	G	95.4	Very high	93.3	Very high	0 Å²	0	27.8 Å²	27.8	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-56.6	-50.8	178.4	0	0	0	0	0	112.4	Y404 L405 F412	Y404-G408 WeakPolarHBondContact O-CA 3.29Å; Y404-G408 PolarHBondContact O-N 3.45Å; L405-G408 PolarHBondContact O-N 3.28Å; G408-F412 VanDerWaalsContact O-CB 3.23Å; G408-F412 WeakPolarHBondContact O-CB 3.32Å; G408-F412 PolarHBondContact O-N 3.39Å; G408-F412 VanDerWaalsContact O-N 3.1Å
409	V	95.4	Very high	92.5	Very high	37 Å²	37	27.2 Å²	27.2	22%	0.224	15%	0.15	C	C	.	.	H	α-helix	trans	-65	-50	178.9	172.9	0	0	0	0	111.2	F147 M151 L405 I407 V411 F412 A413	F147-V409 HydrophobicContact CE2-CG1 4.28Å; F147-V409 HydrophobicContact CE2-CG2 4.29Å; F147-V409 HydrophobicContact CZ-CG1 4.35Å; M151-V409 HydrophobicContact CE-CG2 3.31Å; M151-V409 HydrophobicContact CG-CG2 4.44Å; M151-V409 HydrophobicContact SD-CG2 3.2Å; M151-V409 WeakPolarHBondContact SD-CG2 3.2Å; L405-V409 VanDerWaalsContact O-CB 3.29Å; L405-V409 WeakPolarHBondContact O-CB 3.38Å; L405-V409 WeakPolarHBondContact O-CG2 3.29Å; L405-V409 PolarHBondContact O-N 3.04Å; I407-V409 PolarHBondContact O-N 3.08Å; V409-V411 PolarHBondContact O-N 2.92Å; V409-F412 PolarHBondContact O-N 3.31Å; V409-A413 WeakPolarHBondContact O-CB 3.39Å; V409-A413 PolarHBondContact O-N 3.46Å
410	L	95.6	Very high	92.1	Very high	23 Å²	23	24.7 Å²	24.7	12%	0.12	14%	0.137	C	C	.	.	H	α-helix	trans	-63.3	-44.3	-175.3	-75.8	-174.9	0	0	0	112.1	V329 A333 F338 Y406 I407 S414	V329-L410 HydrophobicContact CG1-CB 3.72Å; V329-L410 HydrophobicContact CG1-CD1 4.14Å; A333-L410 HydrophobicContact CB-CB 4.37Å; A333-L410 HydrophobicContact CB-CD2 4.24Å; F338-L410 HydrophobicContact CE1-CD2 3.96Å; F338-L410 HydrophobicContact CZ-CD2 4.22Å; Y406-L410 HydrophobicContact CD1-CD1 4.02Å; Y406-L410 HydrophobicContact CD2-CD1 4.2Å; Y406-L410 HydrophobicContact CE1-CD1 3.44Å; Y406-L410 VanDerWaalsContact CE1-CD1 3.44Å; Y406-L410 HydrophobicContact CE2-CD1 3.66Å; Y406-L410 HydrophobicContact CE2-CG 4.39Å; Y406-L410 HydrophobicContact CG-CD1 4.37Å; Y406-L410 WeakPolarHBondContact O-CB 3.13Å; Y406-L410 VanDerWaalsContact O-CG 3.31Å; Y406-L410 WeakPolarHBondContact O-CG 3.47Å; Y406-L410 PolarHBondContact O-N 3.4Å; Y406-L410 WeakPolarHBondContact OH-CD1 3.13Å; I407-L410 PolarHBondContact O-N 3.33Å; L410-S414 WeakPolarHBondContact O-CB 3.28Å; L410-S414 PolarHBondContact O-N 3.04Å; L410-S414 PolarHBondContact O-OG 3.46Å
411	V	94.8	Very high	91.7	Very high	14 Å²	14	26 Å²	26	9%	0.085	15%	0.146	C	C	.	.	H	α-helix	trans	-66.3	-44.3	178.7	175.8	0	0	0	0	110.7	P139 V329 I407 V409 F415 F429	P139-V411 HydrophobicContact CB-CB 3.89Å; P139-V411 HydrophobicContact CB-CG1 3.62Å; P139-V411 HydrophobicContact CG-CB 3.62Å; P139-V411 HydrophobicContact CG-CG1 3.67Å; P139-V411 HydrophobicContact CG-CG2 4.06Å; V329-V411 HydrophobicContact CG1-CG2 3.73Å; V329-V411 HydrophobicContact CG2-CG2 4Å; I407-V411 HydrophobicContact CG2-CG2 4.17Å; I407-V411 WeakPolarHBondContact O-CB 3.37Å; I407-V411 VanDerWaalsContact O-CG2 3.29Å; I407-V411 WeakPolarHBondContact O-CG2 3.32Å; I407-V411 PolarHBondContact O-N 2.88Å; V409-V411 PolarHBondContact O-N 2.92Å; V411-F415 PolarHBondContact O-N 3.16Å; V411-F415 VanDerWaalsContact O-N 3.16Å; V411-F429 HydrophobicContact CG1-CB 3.96Å; V411-F429 HydrophobicContact CG1-CD2 4.25Å; V411-F429 HydrophobicContact CG1-CG 4.11Å; V411-F429 HydrophobicContact CG2-CD2 4.17Å; V411-F429 HydrophobicContact CG2-CE2 4.22Å; V411-F429 HydrophobicContact CG2-CG 4.35Å; V411-F429 HydrophobicContact CG2-CZ 4.42Å
412	F	94.4	Very high	91.4	Very high	3 Å²	3	25.5 Å²	25.5	1%	0.013	14%	0.143	C	C	.	.	H	α-helix	trans	-65.9	-42.2	179.7	-174.6	-85.6	0	0	0	112.7	I142 K143 F147 L340 G408 V409 K422 I425	I142-F412 HydrophobicContact CB-CD2 4.49Å; I142-F412 HydrophobicContact CG2-CD2 3.91Å; I142-F412 HydrophobicContact CG2-CE2 4.29Å; I142-F412 HydrophobicContact CG2-CG 4.13Å; K143-F412 HydrophobicContact CB-CE2 4.34Å; F147-F412 HydrophobicContact CB-CD1 4.15Å; F147-F412 HydrophobicContact CB-CE1 3.56Å; F147-F412 HydrophobicContact CB-CZ 3.92Å; F147-F412 AromaticContact CD2-CD1 3.34Å; F147-F412 HydrophobicContact CD2-CD1 3.34Å; F147-F412 AromaticContact CD2-CE1 3.67Å; F147-F412 HydrophobicContact CD2-CE1 3.67Å; F147-F412 HydrophobicContact CD2-CG 4.07Å; F147-F412 HydrophobicContact CE2-CD1 4.01Å; F147-F412 HydrophobicContact CG-CD1 4.02Å; F147-F412 AromaticContact CG-CE1 3.85Å; F147-F412 HydrophobicContact CG-CE1 3.85Å; L340-F412 HydrophobicContact CD2-CD1 4.16Å; L340-F412 HydrophobicContact CD2-CE1 4.18Å; G408-F412 VanDerWaalsContact O-CB 3.23Å; G408-F412 WeakPolarHBondContact O-CB 3.32Å; G408-F412 PolarHBondContact O-N 3.39Å; G408-F412 VanDerWaalsContact O-N 3.1Å; V409-F412 PolarHBondContact O-N 3.31Å; F412-K422 HydrophobicContact CD1-CD 4.5Å; F412-K422 HydrophobicContact CE1-CD 3.78Å; F412-K422 HydrophobicContact CE2-CD 4.18Å; F412-K422 HydrophobicContact CZ-CD 3.61Å; F412-K422 PolarHBondContact O-NZ 3.01Å; F412-I425 HydrophobicContact CD2-CD1 3.74Å; F412-I425 HydrophobicContact CE2-CD1 4.25Å; F412-I425 HydrophobicContact CG-CD1 4.49Å
413	A	93.2	Very high	91	Very high	2 Å²	2	24.1 Å²	24.1	2%	0.017	14%	0.136	C	C	.	.	H	α-helix	trans	-75.5	-32.9	-177.7	0	0	0	0	0	112.8	F338 H339 L340 V409	F338-A413 HydrophobicContact CD1-CB 3.86Å; F338-A413 HydrophobicContact CE1-CB 4.37Å; H339-A413 PolarHBondContact N-O 3.17Å; L340-A413 HydrophobicContact CD1-CB 3.79Å; L340-A413 HydrophobicContact CD2-CB 3.94Å; L340-A413 HydrophobicContact CG-CB 3.91Å; V409-A413 WeakPolarHBondContact O-CB 3.39Å; V409-A413 PolarHBondContact O-N 3.46Å
414	S	92.8	Very high	90.8	Very high	7 Å²	7	24 Å²	24	5%	0.049	14%	0.136	C	C	.	.	H	α-helix	trans	-85.1	-10.7	178.6	64.6	0	0	0	0	114.6	G337 L410	G337-S414 VanDerWaalsContact O-CA 3.25Å; G337-S414 WeakPolarHBondContact O-CA 3.35Å; G337-S414 WeakPolarHBondContact O-CB 3.41Å; L410-S414 WeakPolarHBondContact O-CB 3.28Å; L410-S414 PolarHBondContact O-N 3.04Å; L410-S414 PolarHBondContact O-OG 3.46Å
415	F	91.7	Very high	90.6	Very high	10 Å²	10	24.1 Å²	24.1	4%	0.044	14%	0.136	C	C	.	.	S	Bend	trans	-58.3	123.1	176.9	-167.1	-91.8	0	0	0	110.8	V253 V411 S417 L420 S421 K422 C424 I425 N432	V253-F415 HydrophobicContact CG1-CD2 4.38Å; V253-F415 HydrophobicContact CG1-CE2 3.82Å; V253-F415 HydrophobicContact CG1-CZ 4.35Å; V411-F415 PolarHBondContact O-N 3.16Å; V411-F415 VanDerWaalsContact O-N 3.16Å; F415-S417 PolarHBondContact O-N 3.08Å; F415-S417 VanDerWaalsContact O-N 3.12Å; F415-L420 HydrophobicContact CE1-CB 3.71Å; F415-L420 HydrophobicContact CZ-CB 4.12Å; F415-L420 HydrophobicContact CZ-CD1 4.33Å; F415-S421 VanDerWaalsContact CE1-O 3.28Å; F415-S421 WeakPolarHBondContact CE1-O 3.35Å; F415-K422 HydrophobicContact CD1-CG 4.29Å; F415-K422 PolarHBondContact O-NZ 3.39Å; F415-C424 HydrophobicContact CE1-CB 4.25Å; F415-C424 HydrophobicContact CZ-CB 3.76Å; F415-I425 HydrophobicContact CB-CD1 4.26Å; F415-I425 HydrophobicContact CB-CG1 4.43Å; F415-I425 HydrophobicContact CD1-CG1 4.31Å; F415-I425 HydrophobicContact CD2-CD1 4.39Å; F415-I425 HydrophobicContact CD2-CG1 3.66Å; F415-I425 HydrophobicContact CE2-CG1 3.93Å; F415-I425 HydrophobicContact CG-CD1 4.19Å; F415-I425 HydrophobicContact CG-CG1 3.86Å; F415-I425 HydrophobicContact CZ-CG1 4.37Å; F415-N432 HydrophobicContact CE2-CB 4.41Å
416	P	88.3	Confident	90.4	Very high	9 Å²	9	24.7 Å²	24.7	6%	0.058	14%	0.138	C	C	.	.			trans	-70.8	106.3	-167.9	27.9	-35.1	0	0	0	111.8	T247 V253 L420	T247-P416 HydrophobicContact CG2-CB 4.17Å; T247-P416 HydrophobicContact CG2-CG 3.89Å; V253-P416 HydrophobicContact CB-CG 3.89Å; V253-P416 HydrophobicContact CG1-CG 4.19Å; V253-P416 HydrophobicContact CG2-CG 3.96Å; P416-L420 HydrophobicContact CG-CD1 4.18Å; P416-L420 WeakPolarHBondContact O-CB 3.29Å; P416-L420 PolarHBondContact O-N 2.92Å; P416-L420 VanDerWaalsContact O-N 3.16Å
417	S	85.1	Confident	90.2	Very high	2 Å²	2	21.5 Å²	21.5	1%	0.014	13%	0.127	C	C	.	.	T	Hydrogen-bonded Turn	trans	-145.7	109.6	-172.9	-163.8	0	0	0	0	110.2	H339 F350 F351 F415 L420	H339-S417 WeakPolarHBondContact CB-O 3.42Å; F350-S417 WeakPolarHBondContact CB-OG 3.22Å; F350-S417 PolarHBondContact O-OG 3.08Å; F351-S417 WeakPolarHBondContact CZ-O 3Å; F415-S417 PolarHBondContact O-N 3.08Å; F415-S417 VanDerWaalsContact O-N 3.12Å; S417-L420 WeakPolarHBondContact CA-O 3.38Å; S417-L420 VanDerWaalsContact CB-O 3.29Å; S417-L420 WeakPolarHBondContact CB-O 3.44Å; S417-L420 PolarHBondContact OG-O 3.45Å
418	P	75.9	Confident	90.1	Very high	73 Å²	73	21.5 Å²	21.5	47%	0.474	13%	0.127	S	C	.	.	T	Hydrogen-bonded Turn	cis	-63.6	159.2	-8.8	-18.5	32.8	0	0	0	113.3	F350	F350-P418 HydrophobicContact CD1-CB 4.3Å; F350-P418 HydrophobicContact CD2-CB 4.28Å; F350-P418 HydrophobicContact CD2-CG 3.98Å; F350-P418 HydrophobicContact CE1-CB 4.45Å; F350-P418 HydrophobicContact CE2-CB 4.42Å; F350-P418 HydrophobicContact CE2-CG 4.4Å; F350-P418 HydrophobicContact CG-CB 4.23Å; F350-P418 HydrophobicContact CG-CG 4.17Å
419	P	80.4	Confident	90	Very high	81 Å²	81	21.6 Å²	21.6	53%	0.526	13%	0.127	S	C	.	.	T	Hydrogen-bonded Turn	cis	-98.2	-5.3	14.3	37.6	-36.4	0	0	0	115.8	T247 F350	T247-P419 HydrophobicContact CG2-CG 3.99Å; F350-P419 VanDerWaalsContact CE1-O 3.28Å; F350-P419 WeakPolarHBondContact CE1-O 3.45Å
420	L	84.8	Confident	89.8	Confident	4 Å²	4	19.8 Å²	19.8	2%	0.021	12%	0.116	C	C	.	.	S	Bend	trans	-97.4	145.8	179.2	-68.1	164.9	0	0	0	110.9	L245 T247 V253 C255 F415 P416 S417	L245-L420 HydrophobicContact CD2-CD2 3.57Å; L245-L420 HydrophobicContact CG-CD2 3.96Å; T247-L420 HydrophobicContact CG2-CD1 3.87Å; T247-L420 HydrophobicContact CG2-CG 4.41Å; V253-L420 HydrophobicContact CB-CD1 4.24Å; V253-L420 HydrophobicContact CG1-CD1 4.16Å; C255-L420 HydrophobicContact CB-CD2 3.88Å; F415-L420 HydrophobicContact CE1-CB 3.71Å; F415-L420 HydrophobicContact CZ-CB 4.12Å; F415-L420 HydrophobicContact CZ-CD1 4.33Å; P416-L420 HydrophobicContact CG-CD1 4.18Å; P416-L420 WeakPolarHBondContact O-CB 3.29Å; P416-L420 PolarHBondContact O-N 2.92Å; P416-L420 VanDerWaalsContact O-N 3.16Å; S417-L420 WeakPolarHBondContact CA-O 3.38Å; S417-L420 VanDerWaalsContact CB-O 3.29Å; S417-L420 WeakPolarHBondContact CB-O 3.44Å; S417-L420 PolarHBondContact OG-O 3.45Å
421	S	88	Confident	89.5	Confident	28 Å²	28	19.9 Å²	19.9	20%	0.196	12%	0.117	C	C	.	.			trans	-74.6	138.4	172.4	-177.6	0	0	0	0	110.8	E349 F350 F415 D423 C424	E349-S421 WeakPolarHBondContact O-CB 3.28Å; E349-S421 PolarHBondContact O-OG 3.38Å; F350-S421 WeakPolarHBondContact O-CA 3.39Å; F415-S421 VanDerWaalsContact CE1-O 3.28Å; F415-S421 WeakPolarHBondContact CE1-O 3.35Å; S421-D423 PolarHBondContact O-N 3.26Å; S421-D423 VanDerWaalsContact O-N 3.11Å; S421-D423 PolarHBondContact OG-N 3.43Å; S421-C424 WeakPolarHBondContact O-CB 3.36Å; S421-C424 PolarHBondContact O-N 3.45Å
422	K	89.3	Confident	89.3	Confident	3 Å²	3	19.5 Å²	19.5	1%	0.013	11%	0.114	C	C	.	.	G	3₁₀ helix	trans	-62.5	-15.6	174.7	-70.2	-169.3	-174.2	-68.7	0	113	K143 H339 F350 F351 V352 F412 F415 C424 I425	K143-K422 WeakPolarHBondContact CD-O 3.45Å; H339-K422 VanDerWaalsContact O-CE 3.28Å; H339-K422 WeakPolarHBondContact O-CE 3.44Å; H339-K422 PolarHBondContact O-NZ 3.22Å; F350-K422 PolarHBondContact O-N 2.81Å; F351-K422 HydrophobicContact CD1-CD 4.17Å; V352-K422 HydrophobicContact CB-CB 4.43Å; V352-K422 HydrophobicContact CG2-CB 3.77Å; F412-K422 HydrophobicContact CD1-CD 4.5Å; F412-K422 HydrophobicContact CE1-CD 3.78Å; F412-K422 HydrophobicContact CE2-CD 4.18Å; F412-K422 HydrophobicContact CZ-CD 3.61Å; F412-K422 PolarHBondContact O-NZ 3.01Å; F415-K422 HydrophobicContact CD1-CG 4.29Å; F415-K422 PolarHBondContact O-NZ 3.39Å; K422-C424 PolarHBondContact O-N 3.11Å; K422-I425 WeakPolarHBondContact O-CG1 3.37Å; K422-I425 PolarHBondContact O-N 3.47Å
423	D	88	Confident	89.1	Confident	72 Å²	72	20.2 Å²	20.2	39%	0.385	12%	0.118	S	C	.	.	G	3₁₀ helix	trans	-66	-17.9	170.2	-85.9	-39.7	0	0	0	113.2	K143 V352 R356 S421 I425	K143-D423 PolarHBondContact NZ-O 2.93Å; V352-D423 HydrophobicContact CG2-CB 4.43Å; V352-D423 WeakPolarHBondContact CG2-OD1 3.37Å; R356-D423 IonicContact CZ-OD1 3.14Å; R356-D423 IonicContact NH1-OD1 2.84Å; R356-D423 PolarHBondContact NH1-OD1 3.23Å; R356-D423 IonicContact NH2-OD1 3.99Å; S421-D423 PolarHBondContact O-N 3.26Å; S421-D423 VanDerWaalsContact O-N 3.11Å; S421-D423 PolarHBondContact OG-N 3.43Å; D423-I425 PolarHBondContact O-N 3.42Å
424	C	90.1	Very high	88.7	Confident	15 Å²	15	20.8 Å²	20.8	10%	0.101	12%	0.121	C	C	.	.	G	3₁₀ helix	trans	-71.8	-8.3	175.3	-74.8	0	0	0	0	114.8	C255 F415 S421 K422 E426 N432	C255-C424 HydrophobicContact CB-CB 3.6Å; C255-C424 WeakPolarHBondContact CB-SG 3.44Å; C255-C424 WeakPolarHBondContact SG-CB 3.43Å; C255-C424 CovalentContact SG-SG 2.03Å; C255-C424 PolarHBondContact SG-SG 3.21Å; F415-C424 HydrophobicContact CE1-CB 4.25Å; F415-C424 HydrophobicContact CZ-CB 3.76Å; S421-C424 WeakPolarHBondContact O-CB 3.36Å; S421-C424 PolarHBondContact O-N 3.45Å; K422-C424 PolarHBondContact O-N 3.11Å; C424-E426 PolarHBondContact O-N 2.6Å; C424-E426 VanDerWaalsContact O-N 3.11Å; C424-N432 PolarHBondContact O-ND2 3.38Å
425	I	92.2	Very high	88	Confident	1 Å²	1	21.4 Å²	21.4	1%	0.005	13%	0.125	C	C	.	.			trans	-62.7	118.2	177	-63.7	167.8	0	0	0	108.6	P139 W140 K143 F412 F415 K422 D423	P139-I425 HydrophobicContact CB-CG2 4.09Å; W140-I425 HydrophobicContact CB-CG2 4.46Å; K143-I425 HydrophobicContact CD-CB 3.88Å; K143-I425 PolarHBondContact NZ-O 3.44Å; F412-I425 HydrophobicContact CD2-CD1 3.74Å; F412-I425 HydrophobicContact CE2-CD1 4.25Å; F412-I425 HydrophobicContact CG-CD1 4.49Å; F415-I425 HydrophobicContact CB-CD1 4.26Å; F415-I425 HydrophobicContact CB-CG1 4.43Å; F415-I425 HydrophobicContact CD1-CG1 4.31Å; F415-I425 HydrophobicContact CD2-CD1 4.39Å; F415-I425 HydrophobicContact CD2-CG1 3.66Å; F415-I425 HydrophobicContact CE2-CG1 3.93Å; F415-I425 HydrophobicContact CG-CD1 4.19Å; F415-I425 HydrophobicContact CG-CG1 3.86Å; F415-I425 HydrophobicContact CZ-CG1 4.37Å; K422-I425 WeakPolarHBondContact O-CG1 3.37Å; K422-I425 PolarHBondContact O-N 3.47Å; D423-I425 PolarHBondContact O-N 3.42Å
426	E	91.9	Very high	87.3	Confident	34 Å²	34	23.4 Å²	23.4	16%	0.159	14%	0.14	C	C	.	.			trans	-81.7	158.3	-177.6	-70.2	-62.5	162.5	0	0	111.6	W140 P256 S257 C424 N428 D431 N432	W140-E426 WeakPolarHBondContact CB-O 3.34Å; P256-E426 HydrophobicContact CG-CG 4.06Å; S257-E426 WeakPolarHBondContact CB-OE1 3.49Å; S257-E426 PolarHBondContact N-OE1 3.3Å; S257-E426 PolarHBondContact OG-OE1 2.96Å; C424-E426 PolarHBondContact O-N 2.6Å; C424-E426 VanDerWaalsContact O-N 3.11Å; E426-N428 CarbonylContact O-C 3.19Å; E426-N428 PolarHBondContact O-N 3.05Å; E426-D431 HydrophobicContact CB-CB 4.23Å; E426-D431 HydrophobicContact CG-CB 4.41Å; E426-N432 PolarHBondContact N-OD1 3.35Å
427	Q	92.1	Very high	87.2	Confident	32 Å²	32	24.1 Å²	24.1	15%	0.15	14%	0.144	C	C	.	.	S	Bend	trans	-62.3	-28	-179	-64.6	175.1	8.3	0	0	113.7	L136 S137 W140 N501	L136-Q427 CarbonylContact C-O 3.3Å; S137-Q427 WeakPolarHBondContact CA-O 3.18Å; S137-Q427 VanDerWaalsContact CB-O 3.29Å; S137-Q427 WeakPolarHBondContact CB-O 3.43Å; S137-Q427 PolarHBondContact OG-O 3.39Å; W140-Q427 HydrophobicContact CD2-CB 4.49Å; W140-Q427 HydrophobicContact CD2-CG 3.83Å; W140-Q427 HydrophobicContact CG-CB 4.32Å; W140-Q427 HydrophobicContact CG-CG 3.9Å; W140-Q427 HydrophobicContact CZ2-CG 4.18Å; Q427-N501 VanDerWaalsContact NE2-CG 3.31Å; Q427-N501 PolarHBondContact NE2-OD1 3.08Å; Q427-N501 PolarHBondContact OE1-OD1 3.35Å
428	N	92.6	Very high	87.4	Confident	1 Å²	1	27.7 Å²	27.7	1%	0.005	17%	0.166	C	C	.	.	S	Bend	trans	-110.6	105.3	163.3	168.4	26.2	0	0	0	105.8	L219 N222 E426 L430 D431 I502	L219-N428 HydrophobicContact CD2-CB 4.38Å; N222-N428 PolarHBondContact ND2-ND2 2.76Å; E426-N428 CarbonylContact O-C 3.19Å; E426-N428 PolarHBondContact O-N 3.05Å; N428-L430 PolarHBondContact O-N 2.92Å; N428-L430 WeakPolarHBondContact OD1-CB 3.2Å; N428-L430 PolarHBondContact OD1-N 2.94Å; N428-D431 VanDerWaalsContact ND2-CG 3.31Å; N428-D431 PolarHBondContact ND2-OD1 3.49Å; N428-D431 PolarHBondContact ND2-OD2 2.03Å; N428-D431 WeakPolarHBondContact O-CB 3.25Å; N428-D431 PolarHBondContact O-N 3.41Å; N428-I502 HydrophobicContact CB-CD1 4.1Å
429	F	92.8	Very high	88.2	Confident	2 Å²	2	26.3 Å²	26.3	1%	0.009	15%	0.154	C	C	.	.	G	3₁₀ helix	trans	-60.8	-20	-175.7	77.3	-101.1	0	0	0	112.8	L136 P139 L325 V329 I407 V411 D431 N432 F433	L136-F429 HydrophobicContact CB-CD1 4.47Å; L136-F429 HydrophobicContact CD2-CD1 4.32Å; L136-F429 HydrophobicContact CD2-CE1 3.76Å; L136-F429 HydrophobicContact CD2-CZ 4.22Å; L136-F429 WeakPolarHBondContact O-CD1 3.49Å; L136-F429 PolarHBondContact O-N 3.31Å; P139-F429 HydrophobicContact CG-CB 4.28Å; P139-F429 HydrophobicContact CG-CD1 3.96Å; P139-F429 HydrophobicContact CG-CG 4.34Å; L325-F429 HydrophobicContact CD1-CZ 3.8Å; L325-F429 HydrophobicContact CG-CZ 4.32Å; V329-F429 HydrophobicContact CG2-CE2 3.93Å; V329-F429 HydrophobicContact CG2-CZ 3.7Å; I407-F429 HydrophobicContact CG2-CE1 4.16Å; V411-F429 HydrophobicContact CG1-CB 3.96Å; V411-F429 HydrophobicContact CG1-CD2 4.25Å; V411-F429 HydrophobicContact CG1-CG 4.11Å; V411-F429 HydrophobicContact CG2-CD2 4.17Å; V411-F429 HydrophobicContact CG2-CE2 4.22Å; V411-F429 HydrophobicContact CG2-CG 4.35Å; V411-F429 HydrophobicContact CG2-CZ 4.42Å; F429-D431 PolarHBondContact O-N 3.24Å; F429-N432 WeakPolarHBondContact O-CB 3.36Å; F429-N432 PolarHBondContact O-N 2.82Å; F429-N432 VanDerWaalsContact O-N 3.13Å; F429-F433 AromaticContact CD2-CE2 3.98Å; F429-F433 HydrophobicContact CD2-CE2 3.98Å; F429-F433 HydrophobicContact CE2-CE2 4.19Å
430	L	92.1	Very high	88.6	Confident	0 Å²	0	22.5 Å²	22.5	0%	0	13%	0.129	C	C	.	.	G	3₁₀ helix	trans	-65.6	-20.8	173.5	-66.5	176.8	0	0	0	112.6	L136 F223 L325 L328 N428 N432 F433 R444 L447	L136-L430 HydrophobicContact CD2-CD1 3.83Å; L136-L430 HydrophobicContact CD2-CG 4.06Å; F223-L430 HydrophobicContact CE1-CD1 4.08Å; F223-L430 HydrophobicContact CZ-CD1 4.36Å; L325-L430 HydrophobicContact CD1-CD1 4.47Å; L325-L430 HydrophobicContact CD1-CD2 4.37Å; L328-L430 HydrophobicContact CD2-CD2 4.4Å; N428-L430 PolarHBondContact O-N 2.92Å; N428-L430 WeakPolarHBondContact OD1-CB 3.2Å; N428-L430 PolarHBondContact OD1-N 2.94Å; L430-N432 PolarHBondContact O-N 2.86Å; L430-F433 HydrophobicContact CD2-CD2 4.23Å; L430-F433 PolarHBondContact O-N 3.36Å; L430-R444 HydrophobicContact CD1-CG 4.31Å; L430-R444 PolarHBondContact O-NH2 3.46Å; L430-L447 HydrophobicContact CD1-CD1 3.57Å
431	D	90.1	Very high	89	Confident	25 Å²	25	23.7 Å²	23.7	13%	0.134	13%	0.134	C	C	.	.	G	3₁₀ helix	trans	-75.1	-14	175.3	-65.4	-18.3	0	0	0	112.4	N222 I254 E426 N428 F429 F433	N222-D431 VanDerWaalsContact ND2-CG 3.27Å; N222-D431 PolarHBondContact ND2-OD1 3.14Å; N222-D431 PolarHBondContact ND2-OD2 3.38Å; I254-D431 WeakPolarHBondContact CD1-O 3.25Å; E426-D431 HydrophobicContact CB-CB 4.23Å; E426-D431 HydrophobicContact CG-CB 4.41Å; N428-D431 VanDerWaalsContact ND2-CG 3.31Å; N428-D431 PolarHBondContact ND2-OD1 3.49Å; N428-D431 PolarHBondContact ND2-OD2 2.03Å; N428-D431 WeakPolarHBondContact O-CB 3.25Å; N428-D431 PolarHBondContact O-N 3.41Å; F429-D431 PolarHBondContact O-N 3.24Å; D431-F433 PolarHBondContact O-N 2.97Å
432	N	90.6	Very high	89.2	Confident	5 Å²	5	25.1 Å²	25.1	3%	0.027	14%	0.139	C	C	.	.	G	3₁₀ helix	trans	-77.3	-8.9	168.5	-68.2	115.2	0	0	0	113.1	V253 I254 F415 C424 E426 F429 L430	V253-N432 HydrophobicContact CG1-CB 4.27Å; V253-N432 WeakPolarHBondContact CG1-O 3.37Å; I254-N432 VanDerWaalsContact CG1-O 3.25Å; I254-N432 WeakPolarHBondContact CG1-O 3.32Å; I254-N432 PolarHBondContact N-O 3.45Å; I254-N432 PolarHBondContact O-ND2 3.18Å; I254-N432 VanDerWaalsContact O-ND2 3.07Å; F415-N432 HydrophobicContact CE2-CB 4.41Å; C424-N432 PolarHBondContact O-ND2 3.38Å; E426-N432 PolarHBondContact N-OD1 3.35Å; F429-N432 WeakPolarHBondContact O-CB 3.36Å; F429-N432 PolarHBondContact O-N 2.82Å; F429-N432 VanDerWaalsContact O-N 3.13Å; L430-N432 PolarHBondContact O-N 2.86Å
433	F	89.4	Confident	89.4	Confident	19 Å²	19	25 Å²	25	8%	0.083	14%	0.139	C	C	.	.	S	Bend	trans	-99.7	136	172.7	-61.4	-66.5	0	0	0	110.7	V253 L328 K332 F429 L430 D431 S440 R444	V253-F433 HydrophobicContact CG2-CE1 4.28Å; L328-F433 HydrophobicContact CD2-CE2 4.42Å; K332-F433 HydrophobicContact CB-CZ 4.37Å; K332-F433 HydrophobicContact CD-CE1 4.11Å; K332-F433 HydrophobicContact CG-CE1 4.27Å; K332-F433 HydrophobicContact CG-CZ 4.19Å; F429-F433 AromaticContact CD2-CE2 3.98Å; F429-F433 HydrophobicContact CD2-CE2 3.98Å; F429-F433 HydrophobicContact CE2-CE2 4.19Å; L430-F433 HydrophobicContact CD2-CD2 4.23Å; L430-F433 PolarHBondContact O-N 3.36Å; D431-F433 PolarHBondContact O-N 2.97Å; F433-S440 VanDerWaalsContact CB-OG 3.26Å; F433-S440 WeakPolarHBondContact CB-OG 3.46Å; F433-S440 WeakPolarHBondContact CG-OG 3.47Å; F433-R444 PolarHBondContact O-NH2 3.41Å
434	P	84.8	Confident	89.6	Confident	14 Å²	14	21.7 Å²	21.7	9%	0.091	12%	0.121	C	C	.	.			trans	-63	151.7	-178.5	27.1	-34.4	0	0	0	110.9	P252 I254 S436 D437	P252-P434 HydrophobicContact CB-CG 4.46Å; P252-P434 HydrophobicContact CG-CG 4.1Å; P252-P434 WeakPolarHBondContact O-CD 3.21Å; I254-P434 HydrophobicContact CG2-CB 4.35Å; P434-S436 PolarHBondContact O-N 3.46Å; P434-S436 VanDerWaalsContact O-N 3.15Å; P434-D437 HydrophobicContact CG-CB 4.28Å; P434-D437 PolarHBondContact O-N 2.83Å; P434-D437 VanDerWaalsContact O-N 3.14Å
435	S	77.7	Confident	89.8	Confident	19 Å²	19	24 Å²	24	13%	0.133	13%	0.132	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63	-22.2	-178.9	-48.8	0	0	0	0	113	N226 F230	N226-S435 PolarHBondContact OD1-OG 3.36Å; F230-S435 WeakPolarHBondContact CD2-O 3.27Å
436	S	77.9	Confident	89.8	Confident	52 Å²	52	27.3 Å²	27.3	36%	0.364	15%	0.146	S	C	.	.	T	Hydrogen-bonded Turn	trans	-75.9	-10.8	176.4	54.2	0	0	0	0	115.3	F230 P434 T438	F230-S436 WeakPolarHBondContact CE2-O 3.34Å; P434-S436 PolarHBondContact O-N 3.46Å; P434-S436 VanDerWaalsContact O-N 3.15Å; S436-T438 PolarHBondContact O-N 2.97Å
437	D	86.2	Confident	89.8	Confident	25 Å²	25	25.8 Å²	25.8	13%	0.134	14%	0.139	C	C	.	.			trans	-76.2	111.6	-178.4	179.2	42.8	0	0	0	111.7	K332 P434 L439 S440 F441	K332-D437 WeakPolarHBondContact CE-OD2 3.29Å; K332-D437 IonicContact NZ-OD1 2.8Å; K332-D437 PolarHBondContact NZ-OD1 3.34Å; K332-D437 IonicContact NZ-OD2 2.92Å; K332-D437 PolarHBondContact NZ-OD2 3.37Å; P434-D437 HydrophobicContact CG-CB 4.28Å; P434-D437 PolarHBondContact O-N 2.83Å; P434-D437 VanDerWaalsContact O-N 3.14Å; D437-L439 VanDerWaalsContact C-N 3.3Å; D437-L439 PolarHBondContact O-N 2.92Å; D437-S440 PolarHBondContact O-N 3.07Å; D437-S440 WeakPolarHBondContact OD2-CB 3.36Å; D437-S440 PolarHBondContact OD2-N 3.32Å; D437-S440 PolarHBondContact OD2-OG 3.13Å; D437-F441 WeakPolarHBondContact O-CB 3.49Å; D437-F441 PolarHBondContact O-N 3.29Å
438	T	89.2	Confident	89.8	Confident	77 Å²	77	25.1 Å²	25.1	47%	0.472	14%	0.137	S	C	.	.	H	α-helix	trans	-57.7	-37.9	-176.3	-49.7	0	0	0	0	113.3	S436 F441 I442	S436-T438 PolarHBondContact O-N 2.97Å; T438-F441 WeakPolarHBondContact O-CB 3.45Å; T438-F441 PolarHBondContact O-N 2.84Å; T438-I442 HydrophobicContact CG2-CD1 4.23Å; T438-I442 WeakPolarHBondContact O-CG1 3.47Å; T438-I442 PolarHBondContact O-N 3.02Å
439	L	91.5	Very high	89.7	Confident	44 Å²	44	29.4 Å²	29.4	23%	0.23	16%	0.155	C	C	.	.	H	α-helix	trans	-66.9	-47.1	179.1	-80.8	79	0	0	0	110.8	Y324 L328 F331 D437 F441 I442 A443	Y324-L439 PolarHBondContact OH-O 3.32Å; L328-L439 HydrophobicContact CD1-CB 4.2Å; L328-L439 WeakPolarHBondContact CD1-O 3.26Å; F331-L439 HydrophobicContact CD1-CD2 3.46Å; F331-L439 VanDerWaalsContact CD1-CD2 3.46Å; F331-L439 HydrophobicContact CE1-CD2 3.76Å; F331-L439 HydrophobicContact CG-CD2 4.27Å; D437-L439 VanDerWaalsContact C-N 3.3Å; D437-L439 PolarHBondContact O-N 2.92Å; L439-F441 VanDerWaalsContact C-N 3.29Å; L439-F441 PolarHBondContact O-N 3Å; L439-I442 PolarHBondContact O-N 3.45Å; L439-A443 PolarHBondContact O-N 3.16Å
440	S	90.5	Very high	89.6	Confident	0 Å²	0	29.7 Å²	29.7	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-63.6	-36.2	176.7	-61.8	0	0	0	0	111.9	F433 D437 A443 R444	F433-S440 VanDerWaalsContact CB-OG 3.26Å; F433-S440 WeakPolarHBondContact CB-OG 3.46Å; F433-S440 WeakPolarHBondContact CG-OG 3.47Å; D437-S440 PolarHBondContact O-N 3.07Å; D437-S440 WeakPolarHBondContact OD2-CB 3.36Å; D437-S440 PolarHBondContact OD2-N 3.32Å; D437-S440 PolarHBondContact OD2-OG 3.13Å; S440-A443 PolarHBondContact O-N 3.47Å; S440-R444 WeakPolarHBondContact O-CG 3.48Å; S440-R444 PolarHBondContact O-N 3.05Å
441	F	91.8	Very high	89.5	Confident	30 Å²	30	29.9 Å²	29.9	13%	0.132	16%	0.157	C	C	.	.	H	α-helix	trans	-60.2	-48.5	173.1	170.9	-104.1	0	0	0	112.6	T227 F230 I231 D437 T438 L439 A443 R444 I445	T227-F441 HydrophobicContact CG2-CD2 4.47Å; T227-F441 HydrophobicContact CG2-CE2 3.62Å; T227-F441 HydrophobicContact CG2-CZ 4.28Å; F230-F441 HydrophobicContact CB-CD2 3.61Å; F230-F441 HydrophobicContact CB-CE2 3.85Å; F230-F441 HydrophobicContact CB-CG 4.44Å; F230-F441 HydrophobicContact CD1-CB 4.45Å; F230-F441 AromaticContact CD1-CD1 3.86Å; F230-F441 HydrophobicContact CD1-CD1 3.86Å; F230-F441 AromaticContact CD1-CD2 3.35Å; F230-F441 HydrophobicContact CD1-CD2 3.35Å; F230-F441 AromaticContact CD1-CE1 3.8Å; F230-F441 HydrophobicContact CD1-CE1 3.8Å; F230-F441 AromaticContact CD1-CE2 3.26Å; F230-F441 HydrophobicContact CD1-CE2 3.26Å; F230-F441 AromaticContact CD1-CG 3.63Å; F230-F441 HydrophobicContact CD1-CG 3.63Å; F230-F441 AromaticContact CD1-CZ 3.49Å; F230-F441 HydrophobicContact CD1-CZ 3.49Å; F230-F441 VanDerWaalsContact CD1-CZ 3.49Å; F230-F441 HydrophobicContact CD2-CB 4.41Å; F230-F441 HydrophobicContact CD2-CD2 4.37Å; F230-F441 HydrophobicContact CD2-CG 4.4Å; F230-F441 AromaticContact CE1-CD1 3.69Å; F230-F441 HydrophobicContact CE1-CD1 3.69Å; F230-F441 HydrophobicContact CE1-CD2 4.06Å; F230-F441 AromaticContact CE1-CE1 3.7Å; F230-F441 HydrophobicContact CE1-CE1 3.7Å; F230-F441 HydrophobicContact CE1-CE2 4.06Å; F230-F441 AromaticContact CE1-CG 3.86Å; F230-F441 HydrophobicContact CE1-CG 3.86Å; F230-F441 AromaticContact CE1-CZ 3.87Å; F230-F441 HydrophobicContact CE1-CZ 3.87Å; F230-F441 HydrophobicContact CG-CB 4.33Å; F230-F441 AromaticContact CG-CD2 3.51Å; F230-F441 HydrophobicContact CG-CD2 3.51Å; F230-F441 AromaticContact CG-CE2 3.81Å; F230-F441 HydrophobicContact CG-CE2 3.81Å; F230-F441 AromaticContact CG-CG 3.89Å; F230-F441 HydrophobicContact CG-CG 3.89Å; F230-F441 HydrophobicContact CG-CZ 4.44Å; F230-F441 HydrophobicContact CZ-CD1 4.25Å; F230-F441 HydrophobicContact CZ-CG 4.32Å; I231-F441 HydrophobicContact CG1-CE2 4.39Å; I231-F441 HydrophobicContact CG1-CZ 4.36Å; D437-F441 WeakPolarHBondContact O-CB 3.49Å; D437-F441 PolarHBondContact O-N 3.29Å; T438-F441 WeakPolarHBondContact O-CB 3.45Å; T438-F441 PolarHBondContact O-N 2.84Å; L439-F441 VanDerWaalsContact C-N 3.29Å; L439-F441 PolarHBondContact O-N 3Å; F441-A443 VanDerWaalsContact C-N 3.33Å; F441-A443 PolarHBondContact O-N 3.27Å; F441-R444 PolarHBondContact O-N 3.31Å; F441-I445 HydrophobicContact CD1-CD1 4.21Å; F441-I445 HydrophobicContact CD2-CD1 4.44Å; F441-I445 HydrophobicContact CE1-CD1 3.52Å; F441-I445 HydrophobicContact CE2-CD1 3.81Å; F441-I445 HydrophobicContact CE2-CG1 4.37Å; F441-I445 HydrophobicContact CZ-CD1 3.31Å; F441-I445 HydrophobicContact CZ-CG1 4.32Å; F441-I445 PolarHBondContact O-N 2.87Å
442	I	93	Very high	89.4	Confident	58 Å²	58	30.1 Å²	30.1	30%	0.297	16%	0.158	S	C	.	.	H	α-helix	trans	-62.3	-41.2	177.8	-65.6	165.5	0	0	0	110.7	Y324 T438 L439 R444 I445 F446	Y324-I442 HydrophobicContact CD1-CG2 4.46Å; Y324-I442 HydrophobicContact CE1-CB 4.06Å; Y324-I442 HydrophobicContact CE1-CG2 3.78Å; Y324-I442 HydrophobicContact CE2-CG2 3.86Å; Y324-I442 VanDerWaalsContact CZ-CG2 3.44Å; Y324-I442 WeakPolarHBondContact OH-CB 3.41Å; T438-I442 HydrophobicContact CG2-CD1 4.23Å; T438-I442 WeakPolarHBondContact O-CG1 3.47Å; T438-I442 PolarHBondContact O-N 3.02Å; L439-I442 PolarHBondContact O-N 3.45Å; I442-R444 PolarHBondContact O-N 3.35Å; I442-I445 PolarHBondContact O-N 2.75Å; I442-F446 HydrophobicContact CG2-CD2 4.11Å; I442-F446 HydrophobicContact CG2-CE2 3.75Å; I442-F446 HydrophobicContact CG2-CZ 3.98Å; I442-F446 PolarHBondContact O-N 2.98Å
443	A	92.6	Very high	89.2	Confident	1 Å²	1	30.4 Å²	30.4	1%	0.008	16%	0.16	C	C	.	.	H	α-helix	trans	-60.1	-45.4	175.4	0	0	0	0	0	111.8	Y324 L328 L439 S440 F441 I445 F446 L447	Y324-A443 HydrophobicContact CD1-CB 3.87Å; Y324-A443 HydrophobicContact CE1-CB 3.63Å; Y324-A443 VanDerWaalsContact CE1-N 3.33Å; L328-A443 HydrophobicContact CD1-CB 3.62Å; L439-A443 PolarHBondContact O-N 3.16Å; S440-A443 PolarHBondContact O-N 3.47Å; F441-A443 VanDerWaalsContact C-N 3.33Å; F441-A443 PolarHBondContact O-N 3.27Å; A443-I445 VanDerWaalsContact C-N 3.31Å; A443-I445 PolarHBondContact O-N 3.16Å; A443-F446 PolarHBondContact O-N 2.88Å; A443-L447 WeakPolarHBondContact O-CB 3.34Å; A443-L447 WeakPolarHBondContact O-CG 3.45Å; A443-L447 PolarHBondContact O-N 2.86Å
444	R	93.4	Very high	89.1	Confident	2 Å²	2	30.6 Å²	30.6	1%	0.008	16%	0.163	C	C	.	.	H	α-helix	trans	-61.2	-38.5	178.3	-70.8	170	-179.2	169.5	-0.4	111.6	F223 N226 L430 F433 S440 F441 I442 L448	F223-R444 HydrophobicContact CB-CB 4.35Å; F223-R444 HydrophobicContact CD1-CB 4.08Å; F223-R444 HydrophobicContact CD1-CG 3.71Å; F223-R444 HydrophobicContact CE1-CG 4.13Å; F223-R444 HydrophobicContact CG-CB 4.36Å; F223-R444 HydrophobicContact CG-CG 4.47Å; N226-R444 VanDerWaalsContact CG-NH1 3.34Å; N226-R444 PolarHBondContact OD1-NH1 3.47Å; L430-R444 HydrophobicContact CD1-CG 4.31Å; L430-R444 PolarHBondContact O-NH2 3.46Å; F433-R444 PolarHBondContact O-NH2 3.41Å; S440-R444 WeakPolarHBondContact O-CG 3.48Å; S440-R444 PolarHBondContact O-N 3.05Å; F441-R444 PolarHBondContact O-N 3.31Å; I442-R444 PolarHBondContact O-N 3.35Å; R444-L448 WeakPolarHBondContact O-CB 3.39Å; R444-L448 PolarHBondContact O-N 3.05Å
445	I	93.3	Very high	89.3	Confident	63 Å²	63	29.9 Å²	29.9	32%	0.323	16%	0.158	S	C	.	.	H	α-helix	trans	-65.9	-47.7	175.2	-73.2	179.9	0	0	0	111.8	T227 F441 I442 A443 L447 L448 F449	T227-I445 HydrophobicContact CG2-CD1 4.17Å; T227-I445 HydrophobicContact CG2-CG1 3.99Å; F441-I445 HydrophobicContact CD1-CD1 4.21Å; F441-I445 HydrophobicContact CD2-CD1 4.44Å; F441-I445 HydrophobicContact CE1-CD1 3.52Å; F441-I445 HydrophobicContact CE2-CD1 3.81Å; F441-I445 HydrophobicContact CE2-CG1 4.37Å; F441-I445 HydrophobicContact CZ-CD1 3.31Å; F441-I445 HydrophobicContact CZ-CG1 4.32Å; F441-I445 PolarHBondContact O-N 2.87Å; I442-I445 PolarHBondContact O-N 2.75Å; A443-I445 VanDerWaalsContact C-N 3.31Å; A443-I445 PolarHBondContact O-N 3.16Å; I445-L447 VanDerWaalsContact C-N 3.34Å; I445-L447 PolarHBondContact O-N 3.33Å; I445-L448 PolarHBondContact O-N 2.98Å; I445-F449 WeakPolarHBondContact O-CB 3.32Å; I445-F449 PolarHBondContact O-N 3.04Å
446	F	92.6	Very high	89.8	Confident	70 Å²	70	29.3 Å²	29.3	31%	0.307	15%	0.154	S	C	.	.	H	α-helix	trans	-62.9	-41.9	178.8	-72	-16	0	0	0	112	Y324 I442 A443 Q450	Y324-F446 AromaticContact CD1-CD2 3.91Å; Y324-F446 HydrophobicContact CD1-CD2 3.91Å; Y324-F446 HydrophobicContact CD1-CE2 4.36Å; Y324-F446 HydrophobicContact CD2-CD2 4.21Å; Y324-F446 AromaticContact CD2-CE2 3.88Å; Y324-F446 HydrophobicContact CD2-CE2 3.88Å; Y324-F446 HydrophobicContact CE2-CE2 4.42Å; Y324-F446 AromaticContact CG-CD2 3.69Å; Y324-F446 HydrophobicContact CG-CD2 3.69Å; Y324-F446 AromaticContact CG-CE2 3.85Å; Y324-F446 HydrophobicContact CG-CE2 3.85Å; I442-F446 HydrophobicContact CG2-CD2 4.11Å; I442-F446 HydrophobicContact CG2-CE2 3.75Å; I442-F446 HydrophobicContact CG2-CZ 3.98Å; I442-F446 PolarHBondContact O-N 2.98Å; A443-F446 PolarHBondContact O-N 2.88Å; F446-Q450 VanDerWaalsContact O-CB 3.28Å; F446-Q450 WeakPolarHBondContact O-CB 3.02Å; F446-Q450 PolarHBondContact O-N 3.19Å
447	L	91.6	Very high	90.1	Very high	3 Å²	3	29.3 Å²	29.3	2%	0.016	15%	0.15	C	C	.	.	H	α-helix	trans	-66.2	-41.5	175	-74.7	170.2	0	0	0	112.1	L136 F223 S321 L325 L430 A443 I445 Q450 M451	L136-L447 HydrophobicContact CD1-CD1 4.39Å; L136-L447 HydrophobicContact CD2-CD1 4.07Å; F223-L447 HydrophobicContact CD2-CB 4.2Å; F223-L447 HydrophobicContact CE2-CB 3.8Å; F223-L447 HydrophobicContact CE2-CD1 4.34Å; F223-L447 HydrophobicContact CZ-CB 4.33Å; F223-L447 HydrophobicContact CZ-CD1 4.05Å; S321-L447 VanDerWaalsContact OG-CD2 3.3Å; S321-L447 WeakPolarHBondContact OG-CD2 3.44Å; L325-L447 HydrophobicContact CD1-CD1 4.4Å; L430-L447 HydrophobicContact CD1-CD1 3.57Å; A443-L447 WeakPolarHBondContact O-CB 3.34Å; A443-L447 WeakPolarHBondContact O-CG 3.45Å; A443-L447 PolarHBondContact O-N 2.86Å; I445-L447 VanDerWaalsContact C-N 3.34Å; I445-L447 PolarHBondContact O-N 3.33Å; L447-Q450 PolarHBondContact O-N 3.43Å; L447-M451 HydrophobicContact CB-CE 4.04Å; L447-M451 HydrophobicContact CD2-CE 4.08Å; L447-M451 WeakPolarHBondContact O-CB 3.17Å; L447-M451 VanDerWaalsContact O-CG 3.23Å; L447-M451 WeakPolarHBondContact O-CG 3.46Å; L447-M451 PolarHBondContact O-N 3.35Å
448	L	92.6	Very high	90	Very high	18 Å²	18	29.4 Å²	29.4	9%	0.094	15%	0.15	C	C	.	.	H	α-helix	trans	-60.2	-49.3	176.6	177.5	62.9	0	0	0	110.8	M220 F223 L224 R444 I445 M451 M452	M220-L448 HydrophobicContact CB-CD1 3.89Å; M220-L448 HydrophobicContact CG-CD1 3.98Å; F223-L448 HydrophobicContact CB-CB 4.18Å; F223-L448 HydrophobicContact CB-CD1 4.4Å; L224-L448 HydrophobicContact CB-CD2 4.39Å; L224-L448 HydrophobicContact CD1-CD2 4.26Å; R444-L448 WeakPolarHBondContact O-CB 3.39Å; R444-L448 PolarHBondContact O-N 3.05Å; I445-L448 PolarHBondContact O-N 2.98Å; L448-M451 PolarHBondContact O-N 3.16Å; L448-M452 HydrophobicContact CG-SD 4.46Å; L448-M452 WeakPolarHBondContact O-CG 3.46Å; L448-M452 PolarHBondContact O-N 3.4Å
449	F	89.7	Confident	89.8	Confident	91 Å²	91	25.9 Å²	25.9	40%	0.399	13%	0.129	S	C	.	.	H	α-helix	trans	-70.1	-35.1	-178.7	-170	-125.8	0	0	0	112.3	L317 I445 M452 T453	L317-F449 HydrophobicContact CD2-CD1 3.02Å; L317-F449 HydrophobicContact CD2-CE1 3.03Å; L317-F449 HydrophobicContact CD2-CG 4.26Å; L317-F449 HydrophobicContact CD2-CZ 4.29Å; L317-F449 HydrophobicContact CG-CD1 4.24Å; L317-F449 HydrophobicContact CG-CE1 4.49Å; I445-F449 WeakPolarHBondContact O-CB 3.32Å; I445-F449 PolarHBondContact O-N 3.04Å; F449-M452 PolarHBondContact O-N 3.01Å; F449-T453 HydrophobicContact CE2-CG2 4.45Å; F449-T453 HydrophobicContact CZ-CG2 4.47Å; F449-T453 WeakPolarHBondContact O-CG2 3.36Å; F449-T453 PolarHBondContact O-N 3.06Å; F449-T453 PolarHBondContact O-OG1 3.49Å
450	Q	90.3	Very high	89.4	Confident	8 Å²	8	26.6 Å²	26.6	4%	0.037	13%	0.129	C	C	.	.	H	α-helix	trans	-57.2	-50.9	167.7	175.1	-175.8	0.8	0	0	111.2	G318 S321 F446 L447 M452 T453 V454	G318-Q450 VanDerWaalsContact CA-CD 3.48Å; S321-Q450 PolarHBondContact OG-OE1 3.28Å; F446-Q450 VanDerWaalsContact O-CB 3.28Å; F446-Q450 WeakPolarHBondContact O-CB 3.02Å; F446-Q450 PolarHBondContact O-N 3.19Å; L447-Q450 PolarHBondContact O-N 3.43Å; Q450-M452 VanDerWaalsContact C-N 3.34Å; Q450-M452 PolarHBondContact O-N 3.35Å; Q450-T453 PolarHBondContact O-N 2.89Å; Q450-T453 VanDerWaalsContact O-N 3.16Å; Q450-T453 PolarHBondContact O-OG1 3.48Å; Q450-V454 HydrophobicContact CG-CG2 4.43Å; Q450-V454 WeakPolarHBondContact O-CG2 2.97Å; Q450-V454 PolarHBondContact O-N 3.23Å
451	M	90.1	Very high	88.9	Confident	3 Å²	3	29.8 Å²	29.8	2%	0.015	15%	0.145	C	C	.	.	H	α-helix	trans	-65.5	-37.7	-177.6	-70.5	172.8	-156.6	0	0	112.1	T133 Y216 L219 M220 F223 L447 L448 T453 V454 Y455	T133-M451 HydrophobicContact CG2-CE 3.25Å; T133-M451 HydrophobicContact CG2-CG 4.24Å; T133-M451 HydrophobicContact CG2-SD 3.59Å; T133-M451 VanDerWaalsContact CG2-SD 3.59Å; Y216-M451 HydrophobicContact CD2-CB 4.19Å; Y216-M451 HydrophobicContact CD2-CG 4.21Å; Y216-M451 HydrophobicContact CE2-CG 4.29Å; L219-M451 HydrophobicContact CB-SD 3.98Å; M220-M451 HydrophobicContact CG-CB 3.56Å; M220-M451 HydrophobicContact CG-SD 4.31Å; M220-M451 HydrophobicContact SD-CB 3.76Å; F223-M451 HydrophobicContact CD2-CE 4.46Å; F223-M451 HydrophobicContact CD2-SD 4.18Å; F223-M451 HydrophobicContact CE2-CE 3.6Å; F223-M451 HydrophobicContact CE2-SD 3.78Å; F223-M451 HydrophobicContact CZ-CE 4.47Å; L447-M451 HydrophobicContact CB-CE 4.04Å; L447-M451 HydrophobicContact CD2-CE 4.08Å; L447-M451 WeakPolarHBondContact O-CB 3.17Å; L447-M451 VanDerWaalsContact O-CG 3.23Å; L447-M451 WeakPolarHBondContact O-CG 3.46Å; L447-M451 PolarHBondContact O-N 3.35Å; L448-M451 PolarHBondContact O-N 3.16Å; M451-T453 VanDerWaalsContact C-N 3.26Å; M451-T453 PolarHBondContact O-N 2.88Å; M451-V454 PolarHBondContact O-N 2.9Å; M451-Y455 WeakPolarHBondContact O-CB 3.37Å; M451-Y455 PolarHBondContact O-N 2.96Å
452	M	88.9	Confident	88.6	Confident	31 Å²	31	28.4 Å²	28.4	15%	0.153	14%	0.14	C	C	.	.	H	α-helix	trans	-60.4	-32.8	174.2	-76.4	-177.2	54.9	0	0	113.4	M220 L298 L299 L448 F449 Q450 P456	M220-M452 HydrophobicContact SD-CG 4.12Å; L298-M452 HydrophobicContact CD1-CE 4.18Å; L298-M452 HydrophobicContact CD2-CE 3.25Å; L298-M452 HydrophobicContact CD2-SD 3.73Å; L298-M452 HydrophobicContact CG-CE 3.69Å; L299-M452 HydrophobicContact CD2-CB 4.27Å; L299-M452 HydrophobicContact CD2-CG 4.11Å; L448-M452 HydrophobicContact CG-SD 4.46Å; L448-M452 WeakPolarHBondContact O-CG 3.46Å; L448-M452 PolarHBondContact O-N 3.4Å; F449-M452 PolarHBondContact O-N 3.01Å; Q450-M452 VanDerWaalsContact C-N 3.34Å; Q450-M452 PolarHBondContact O-N 3.35Å; M452-P456 WeakPolarHBondContact O-CD 3.19Å
453	T	87.1	Confident	88.2	Confident	10 Å²	10	26 Å²	26	6%	0.061	13%	0.127	C	C	.	.	H	α-helix	trans	-85	-31.4	179.5	58.4	0	0	0	0	112.7	F314 F449 Q450 M451	F314-T453 HydrophobicContact CB-CG2 3.8Å; F314-T453 HydrophobicContact CG-CG2 4.15Å; F449-T453 HydrophobicContact CE2-CG2 4.45Å; F449-T453 HydrophobicContact CZ-CG2 4.47Å; F449-T453 WeakPolarHBondContact O-CG2 3.36Å; F449-T453 PolarHBondContact O-N 3.06Å; F449-T453 PolarHBondContact O-OG1 3.49Å; Q450-T453 PolarHBondContact O-N 2.89Å; Q450-T453 VanDerWaalsContact O-N 3.16Å; Q450-T453 PolarHBondContact O-OG1 3.48Å; M451-T453 VanDerWaalsContact C-N 3.26Å; M451-T453 PolarHBondContact O-N 2.88Å
454	V	86.4	Confident	87.5	Confident	23 Å²	23	28.2 Å²	28.2	14%	0.139	14%	0.14	C	C	.	.	H	α-helix	trans	-80.4	-31.4	178.3	176.4	0	0	0	0	112	Y216 Q450 M451 L457 L458	Y216-V454 HydrophobicContact CE2-CB 3.96Å; Y216-V454 HydrophobicContact CE2-CG1 3.65Å; Q450-V454 HydrophobicContact CG-CG2 4.43Å; Q450-V454 WeakPolarHBondContact O-CG2 2.97Å; Q450-V454 PolarHBondContact O-N 3.23Å; M451-V454 PolarHBondContact O-N 2.9Å; V454-L457 WeakPolarHBondContact O-CB 3.38Å; V454-L457 PolarHBondContact O-N 3.29Å; V454-L458 HydrophobicContact CG1-CD1 4.23Å; V454-L458 HydrophobicContact CG1-CG 4.18Å; V454-L458 PolarHBondContact O-N 3.16Å; V454-L458 VanDerWaalsContact O-N 3.08Å
455	Y	89.4	Confident	86.8	Confident	0 Å²	0	30.2 Å²	30.2	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-58	-45.3	-177.9	-175.5	-97.7	0	0	0	113.6	M213 Y216 W217 M220 L299 L303 M451 L457 L458 G459	M213-Y455 HydrophobicContact CB-CD2 4.36Å; M213-Y455 HydrophobicContact CB-CE2 3.68Å; M213-Y455 HydrophobicContact CE-CD1 4.44Å; M213-Y455 HydrophobicContact CE-CD2 4.25Å; M213-Y455 HydrophobicContact CE-CE1 3.94Å; M213-Y455 HydrophobicContact CE-CE2 3.7Å; M213-Y455 HydrophobicContact CG-CD2 4.33Å; M213-Y455 HydrophobicContact CG-CE2 4Å; M213-Y455 WeakPolarHBondContact O-CE2 3.41Å; Y216-Y455 HydrophobicContact CD2-CD2 4.5Å; W217-Y455 AromaticContact CE3-CE1 3.92Å; W217-Y455 HydrophobicContact CE3-CE1 3.92Å; W217-Y455 AromaticContact CE3-CE2 3.99Å; W217-Y455 HydrophobicContact CE3-CE2 3.99Å; W217-Y455 AromaticContact CE3-CZ 3.47Å; W217-Y455 VanDerWaalsContact CE3-CZ 3.47Å; W217-Y455 VanDerWaalsContact CE3-OH 3.28Å; W217-Y455 AromaticContact CZ3-CE1 3.68Å; W217-Y455 HydrophobicContact CZ3-CE1 3.68Å; W217-Y455 AromaticContact CZ3-CZ 3.71Å; M220-Y455 HydrophobicContact CE-CD2 3.91Å; M220-Y455 HydrophobicContact CE-CE2 4.39Å; M220-Y455 HydrophobicContact CE-CG 4.02Å; L299-Y455 HydrophobicContact CB-CD1 4.38Å; L299-Y455 HydrophobicContact CB-CE1 4.39Å; L299-Y455 HydrophobicContact CD1-CD1 4.09Å; L299-Y455 HydrophobicContact CD1-CE1 4.3Å; L299-Y455 HydrophobicContact CD2-CD1 4.47Å; L303-Y455 HydrophobicContact CD1-CD1 4.33Å; L303-Y455 HydrophobicContact CD1-CE1 3.6Å; L303-Y455 HydrophobicContact CD2-CD1 4.22Å; L303-Y455 HydrophobicContact CD2-CE1 4.13Å; L303-Y455 HydrophobicContact CG-CD1 4.31Å; L303-Y455 HydrophobicContact CG-CE1 4.07Å; M451-Y455 WeakPolarHBondContact O-CB 3.37Å; M451-Y455 PolarHBondContact O-N 2.96Å; Y455-L457 VanDerWaalsContact C-N 3.3Å; Y455-L457 PolarHBondContact O-N 3.48Å; Y455-L458 PolarHBondContact O-N 3.23Å; Y455-G459 PolarHBondContact O-N 2.93Å
456	P	88.6	Confident	86.4	Confident	7 Å²	7	29.1 Å²	29.1	5%	0.045	14%	0.144	C	C	.	.	H	α-helix	trans	-62	-32.6	172.8	-25.1	35.2	0	0	0	114.5	L302 F311 M452 G459 Y460	L302-P456 HydrophobicContact CB-CG 3.97Å; F311-P456 HydrophobicContact CD1-CG 4.42Å; F311-P456 HydrophobicContact CD2-CB 3.85Å; F311-P456 HydrophobicContact CD2-CG 4.46Å; F311-P456 HydrophobicContact CE1-CG 4.12Å; F311-P456 HydrophobicContact CE2-CB 3.71Å; F311-P456 HydrophobicContact CE2-CG 4.15Å; F311-P456 HydrophobicContact CG-CB 4.3Å; F311-P456 HydrophobicContact CZ-CB 4.08Å; F311-P456 HydrophobicContact CZ-CG 3.98Å; M452-P456 WeakPolarHBondContact O-CD 3.19Å; P456-G459 PolarHBondContact O-N 3.31Å; P456-Y460 WeakPolarHBondContact O-CB 3.27Å; P456-Y460 PolarHBondContact O-N 3.48Å
457	L	83.3	Confident	85.9	Confident	52 Å²	52	26.1 Å²	26.1	27%	0.272	13%	0.131	S	C	.	.	H	α-helix	trans	-67.4	-43.2	177.4	-178.1	65.5	0	0	0	111.1	P308 V454 Y455 Y460 L461	P308-L457 HydrophobicContact CB-CD1 3.82Å; V454-L457 WeakPolarHBondContact O-CB 3.38Å; V454-L457 PolarHBondContact O-N 3.29Å; Y455-L457 VanDerWaalsContact C-N 3.3Å; Y455-L457 PolarHBondContact O-N 3.48Å; L457-Y460 PolarHBondContact O-N 3.34Å; L457-L461 WeakPolarHBondContact O-CG 3.39Å; L457-L461 PolarHBondContact O-N 2.77Å
458	L	83.7	Confident	85.2	Confident	27 Å²	27	27 Å²	27	14%	0.141	14%	0.142	C	C	.	.	H	α-helix	trans	-63.7	-42	174.6	-64.8	178.3	0	0	0	111.6	L209 A212 M213 Y216 V454 Y455 Y460 L461 A462	L209-L458 HydrophobicContact CD2-CD2 4.33Å; A212-L458 HydrophobicContact CB-CD1 4.32Å; M213-L458 HydrophobicContact CG-CB 3.91Å; M213-L458 HydrophobicContact CG-CD1 4.46Å; M213-L458 HydrophobicContact SD-CB 4.25Å; Y216-L458 HydrophobicContact CD2-CD1 4.24Å; Y216-L458 HydrophobicContact CE2-CD1 3.98Å; V454-L458 HydrophobicContact CG1-CD1 4.23Å; V454-L458 HydrophobicContact CG1-CG 4.18Å; V454-L458 PolarHBondContact O-N 3.16Å; V454-L458 VanDerWaalsContact O-N 3.08Å; Y455-L458 PolarHBondContact O-N 3.23Å; L458-Y460 VanDerWaalsContact C-N 3.33Å; L458-Y460 PolarHBondContact O-N 3.39Å; L458-L461 HydrophobicContact CD2-CD1 4.49Å; L458-L461 PolarHBondContact O-N 3.32Å; L458-A462 PolarHBondContact O-N 2.88Å
459	G	85.4	Confident	84.5	Confident	2 Å²	2	28.8 Å²	28.8	2%	0.021	15%	0.149	C	C	.	.	H	α-helix	trans	-60.7	-40.9	174.3	0	0	0	0	0	112.8	Y455 P456 A462 R463	Y455-G459 PolarHBondContact O-N 2.93Å; P456-G459 PolarHBondContact O-N 3.31Å; G459-A462 PolarHBondContact O-N 2.84Å; G459-R463 WeakPolarHBondContact O-CB 3.41Å; G459-R463 PolarHBondContact O-N 3.34Å
460	Y	83.1	Confident	84.1	Confident	59 Å²	59	28.7 Å²	28.7	23%	0.231	15%	0.152	C	C	.	.	H	α-helix	trans	-62.6	-42.6	173.7	178.8	-93.4	0	0	0	112.2	P308 P456 L457 L458 R463 V464	P308-Y460 HydrophobicContact CB-CD1 4.21Å; P308-Y460 HydrophobicContact CB-CG 4.15Å; P308-Y460 HydrophobicContact CG-CD1 3.75Å; P308-Y460 HydrophobicContact CG-CD2 4.29Å; P308-Y460 HydrophobicContact CG-CE1 3.79Å; P308-Y460 HydrophobicContact CG-CE2 4.32Å; P308-Y460 HydrophobicContact CG-CG 4.02Å; P456-Y460 WeakPolarHBondContact O-CB 3.27Å; P456-Y460 PolarHBondContact O-N 3.48Å; L457-Y460 PolarHBondContact O-N 3.34Å; L458-Y460 VanDerWaalsContact C-N 3.33Å; L458-Y460 PolarHBondContact O-N 3.39Å; Y460-R463 WeakPolarHBondContact O-CB 3.32Å; Y460-R463 PolarHBondContact O-N 2.8Å; Y460-V464 HydrophobicContact CD1-CG2 4.03Å; Y460-V464 HydrophobicContact CE1-CG2 3.52Å; Y460-V464 HydrophobicContact CE2-CG2 4.21Å; Y460-V464 WeakPolarHBondContact O-CG2 3.43Å; Y460-V464 PolarHBondContact O-N 3.43Å
461	L	80.6	Confident	83.7	Confident	67 Å²	67	32.8 Å²	32.8	35%	0.351	17%	0.17	S	C	.	.	H	α-helix	trans	-63	-44.7	176.3	-70.2	172.2	0	0	0	111.8	L209 L457 L458 R463 V464 Q465	L209-L461 HydrophobicContact CD1-CB 4.31Å; L209-L461 HydrophobicContact CD2-CB 4.5Å; L457-L461 WeakPolarHBondContact O-CG 3.39Å; L457-L461 PolarHBondContact O-N 2.77Å; L458-L461 HydrophobicContact CD2-CD1 4.49Å; L458-L461 PolarHBondContact O-N 3.32Å; L461-R463 VanDerWaalsContact C-N 3.27Å; L461-R463 PolarHBondContact O-N 3.45Å; L461-V464 PolarHBondContact O-N 3.12Å; L461-Q465 WeakPolarHBondContact O-CG 3.17Å; L461-Q465 PolarHBondContact O-N 2.97Å
462	A	84.3	Confident	82.7	Confident	2 Å²	2	35.6 Å²	35.6	2%	0.017	20%	0.199	C	C	.	.	H	α-helix	trans	-60.1	-39.8	175.7	0	0	0	0	0	111.4	L209 L458 G459 Q465 L466 I488	L209-A462 HydrophobicContact CB-CB 4.38Å; L209-A462 HydrophobicContact CD1-CB 4.21Å; L458-A462 PolarHBondContact O-N 2.88Å; G459-A462 PolarHBondContact O-N 2.84Å; A462-Q465 PolarHBondContact O-N 2.9Å; A462-L466 VanDerWaalsContact O-CB 3.32Å; A462-L466 WeakPolarHBondContact O-CB 3.48Å; A462-L466 PolarHBondContact O-N 2.96Å; A462-I488 HydrophobicContact CB-CD1 4.36Å
463	R	84.4	Confident	81.9	Confident	8 Å²	8	39.2 Å²	39.2	3%	0.03	22%	0.219	C	C	.	.	H	α-helix	trans	-63.2	-48.2	175.6	-172.3	-172.4	117.7	-156.1	-8.4	112.5	G459 Y460 L461 Q465 L466 L467 I474 Y475 V481 L484	G459-R463 WeakPolarHBondContact O-CB 3.41Å; G459-R463 PolarHBondContact O-N 3.34Å; Y460-R463 WeakPolarHBondContact O-CB 3.32Å; Y460-R463 PolarHBondContact O-N 2.8Å; L461-R463 VanDerWaalsContact C-N 3.27Å; L461-R463 PolarHBondContact O-N 3.45Å; R463-Q465 VanDerWaalsContact C-N 3.3Å; R463-Q465 PolarHBondContact O-N 2.96Å; R463-L466 PolarHBondContact O-N 3.19Å; R463-L467 HydrophobicContact CG-CB 4.47Å; R463-L467 HydrophobicContact CG-CD1 3.49Å; R463-L467 VanDerWaalsContact CG-CD1 3.49Å; R463-L467 HydrophobicContact CG-CG 3.99Å; R463-L467 VanDerWaalsContact O-CB 3.29Å; R463-L467 WeakPolarHBondContact O-CB 3.44Å; R463-L467 PolarHBondContact O-N 2.9Å; R463-I474 VanDerWaalsContact CZ-O 3.29Å; R463-I474 PolarHBondContact NE-O 3.48Å; R463-I474 PolarHBondContact NH2-O 3.34Å; R463-Y475 VanDerWaalsContact CZ-CD2 3.41Å; R463-Y475 VanDerWaalsContact NH2-CD2 3.29Å; R463-V481 HydrophobicContact CG-CG2 4.48Å; R463-L484 HydrophobicContact CB-CD2 4.13Å; R463-L484 HydrophobicContact CG-CD2 4.19Å
464	V	78.4	Confident	81	Confident	47 Å²	47	42.8 Å²	42.8	29%	0.285	24%	0.237	S	C	.	.	H	α-helix	trans	-60.3	-43.6	179.2	171.3	0	0	0	0	110.3	Y460 L461 G468 I474	Y460-V464 HydrophobicContact CD1-CG2 4.03Å; Y460-V464 HydrophobicContact CE1-CG2 3.52Å; Y460-V464 HydrophobicContact CE2-CG2 4.21Å; Y460-V464 WeakPolarHBondContact O-CG2 3.43Å; Y460-V464 PolarHBondContact O-N 3.43Å; L461-V464 PolarHBondContact O-N 3.12Å; V464-G468 VanDerWaalsContact O-CA 3.27Å; V464-G468 WeakPolarHBondContact O-CA 3.23Å; V464-G468 PolarHBondContact O-N 3.13Å; V464-I474 HydrophobicContact CG2-CG2 3.83Å
465	Q	79.6	Confident	80.5	Confident	43 Å²	43	45 Å²	45	20%	0.201	24%	0.244	C	C	.	.	H	α-helix	trans	-67.8	-46.8	179.9	-70.2	-175.5	-2.4	0	0	112.4	L202 S205 L206 L461 A462 R463 H469	L202-Q465 HydrophobicContact CD1-CB 3.91Å; L202-Q465 WeakPolarHBondContact CD1-O 3.39Å; S205-Q465 VanDerWaalsContact OG-CD 3.27Å; S205-Q465 PolarHBondContact OG-NE2 3.4Å; S205-Q465 VanDerWaalsContact OG-NE2 3.15Å; S205-Q465 PolarHBondContact OG-OE1 3.28Å; L206-Q465 HydrophobicContact CD2-CB 4.38Å; L461-Q465 WeakPolarHBondContact O-CG 3.17Å; L461-Q465 PolarHBondContact O-N 2.97Å; A462-Q465 PolarHBondContact O-N 2.9Å; R463-Q465 VanDerWaalsContact C-N 3.3Å; R463-Q465 PolarHBondContact O-N 2.96Å; Q465-H469 WeakPolarHBondContact O-CB 3.01Å; Q465-H469 PolarHBondContact O-N 3.3Å
466	L	83.9	Confident	79.7	Confident	41 Å²	41	47.1 Å²	47.1	22%	0.215	26%	0.258	C	S	.	.	H	α-helix	trans	-75.6	-57.3	-177.4	-171.5	79.8	0	0	0	112.1	L206 A462 R463 H469 I470 L484	L206-L466 HydrophobicContact CD1-CD1 3.51Å; L206-L466 HydrophobicContact CD2-CB 4.12Å; L206-L466 HydrophobicContact CD2-CD1 4.46Å; A462-L466 VanDerWaalsContact O-CB 3.32Å; A462-L466 WeakPolarHBondContact O-CB 3.48Å; A462-L466 PolarHBondContact O-N 2.96Å; R463-L466 PolarHBondContact O-N 3.19Å; L466-H469 PolarHBondContact O-N 2.97Å; L466-I470 HydrophobicContact CD1-CD1 3.82Å; L466-I470 HydrophobicContact CG-CD1 3.88Å; L466-I470 WeakPolarHBondContact O-CB 3.3Å; L466-I470 WeakPolarHBondContact O-CG1 3.39Å; L466-I470 PolarHBondContact O-N 3.17Å; L466-L484 HydrophobicContact CD2-CD1 3.35Å; L466-L484 HydrophobicContact CD2-CD2 3.95Å; L466-L484 HydrophobicContact CD2-CG 4.25Å
467	L	82.9	Confident	79.3	Confident	6 Å²	6	49.1 Å²	49.1	3%	0.031	27%	0.272	C	S	.	.	H	α-helix	trans	-73.1	-37.4	-174.1	-59.7	-174.1	0	0	0	111.7	R463 H469 I470 F471 D473 P476 V481 L484	R463-L467 HydrophobicContact CG-CB 4.47Å; R463-L467 HydrophobicContact CG-CD1 3.49Å; R463-L467 VanDerWaalsContact CG-CD1 3.49Å; R463-L467 HydrophobicContact CG-CG 3.99Å; R463-L467 VanDerWaalsContact O-CB 3.29Å; R463-L467 WeakPolarHBondContact O-CB 3.44Å; R463-L467 PolarHBondContact O-N 2.9Å; L467-H469 PolarHBondContact O-N 2.89Å; L467-I470 PolarHBondContact O-N 2.85Å; L467-F471 HydrophobicContact CB-CD2 4.37Å; L467-F471 HydrophobicContact CD2-CD2 3.83Å; L467-F471 HydrophobicContact CD2-CE2 3.77Å; L467-F471 WeakPolarHBondContact O-CB 3.28Å; L467-F471 PolarHBondContact O-N 2.96Å; L467-D473 CarbonylContact C-O 3.57Å; L467-P476 HydrophobicContact CD1-CG 4.19Å; L467-V481 HydrophobicContact CD1-CG2 3.69Å; L467-L484 HydrophobicContact CD1-CD2 4.37Å; L467-L484 HydrophobicContact CD2-CD2 4.41Å; L467-L484 HydrophobicContact CG-CD2 4.1Å
468	G	75.6	Confident	79.3	Confident	23 Å²	23	52.2 Å²	52.2	24%	0.237	29%	0.287	C	S	.	.	H	α-helix	trans	-61.9	-34.9	174.9	0	0	0	0	0	112	V464 G472	V464-G468 VanDerWaalsContact O-CA 3.27Å; V464-G468 WeakPolarHBondContact O-CA 3.23Å; V464-G468 PolarHBondContact O-N 3.13Å; G468-G472 VanDerWaalsContact O-CA 3.24Å; G468-G472 WeakPolarHBondContact O-CA 3.34Å; G468-G472 PolarHBondContact O-N 3.34Å
469	H	79.4	Confident	79.5	Confident	54 Å²	54	57.2 Å²	57.2	25%	0.25	31%	0.308	C	S	.	.	H	α-helix	trans	-77.3	-44.4	177	-171.2	64	0	0	0	113.4	Q198 W199 L202 Q465 L466 L467	Q198-H469 PolarHBondContact NE2-CE1 2.81Å; Q198-H469 PolarHBondContact NE2-ND1 3.24Å; W199-H469 AromaticContact CE2-NE2 3.7Å; W199-H469 AromaticContact CZ2-NE2 3.82Å; L202-H469 HydrophobicContact CD2-CB 3.83Å; L202-H469 WeakPolarHBondContact CD2-CD2 3.34Å; Q465-H469 WeakPolarHBondContact O-CB 3.01Å; Q465-H469 PolarHBondContact O-N 3.3Å; L466-H469 PolarHBondContact O-N 2.97Å; L467-H469 PolarHBondContact O-N 2.89Å
470	I	81.3	Confident	79.6	Confident	89 Å²	89	60.6 Å²	60.6	46%	0.456	32%	0.323	S	S	.	.	H	α-helix	trans	-76	-42.4	-175.3	-65.2	173.7	0	0	0	111.8	L466 L467	L466-I470 HydrophobicContact CD1-CD1 3.82Å; L466-I470 HydrophobicContact CG-CD1 3.88Å; L466-I470 WeakPolarHBondContact O-CB 3.3Å; L466-I470 WeakPolarHBondContact O-CG1 3.39Å; L466-I470 PolarHBondContact O-N 3.17Å; L467-I470 PolarHBondContact O-N 2.85Å
471	F	80.4	Confident	79.7	Confident	94 Å²	94	57.8 Å²	57.8	41%	0.412	31%	0.312	S	S	.	.	H	α-helix	trans	-107.8	-6.1	-171.4	-63.3	-79.9	0	0	0	113.6	L467 D473 P476 H480	L467-F471 HydrophobicContact CB-CD2 4.37Å; L467-F471 HydrophobicContact CD2-CD2 3.83Å; L467-F471 HydrophobicContact CD2-CE2 3.77Å; L467-F471 WeakPolarHBondContact O-CB 3.28Å; L467-F471 PolarHBondContact O-N 2.96Å; F471-D473 PolarHBondContact O-N 3.39Å; F471-P476 HydrophobicContact CB-CB 4.12Å; F471-P476 HydrophobicContact CB-CG 4.21Å; F471-P476 HydrophobicContact CD2-CG 4.14Å; F471-P476 HydrophobicContact CG-CB 4.26Å; F471-P476 HydrophobicContact CG-CG 4.15Å; F471-H480 AromaticContact CE1-CD2 3.92Å; F471-H480 AromaticContact CE1-NE2 3.89Å; F471-H480 AromaticContact CE2-CD2 3.95Å; F471-H480 AromaticContact CZ-CD2 3.46Å; F471-H480 VanDerWaalsContact CZ-CD2 3.46Å; F471-H480 WeakPolarHBondContact CZ-CD2 3.5Å; F471-H480 AromaticContact CZ-NE2 3.84Å
472	G	70.5	Confident	80.2	Confident	62 Å²	62	58.2 Å²	58.2	64%	0.639	31%	0.314	S	S	*	.	S	Bend	trans	73.2	-16.8	-175.2	0	0	0	0	0	114.4	G468	G468-G472 VanDerWaalsContact O-CA 3.24Å; G468-G472 WeakPolarHBondContact O-CA 3.34Å; G468-G472 PolarHBondContact O-N 3.34Å
473	D	71.9	Confident	80.5	Confident	107 Å²	107	61.4 Å²	61.4	57%	0.572	33%	0.331	S	S	*	.	S	Bend	trans	-112.1	139.3	179.2	-79.9	-38.6	0	0	0	112.5	L467 F471 Y475	L467-D473 CarbonylContact C-O 3.57Å; F471-D473 PolarHBondContact O-N 3.39Å; D473-Y475 PolarHBondContact O-N 3.29Å
474	I	68.1	Low	80.8	Confident	85 Å²	85	61.9 Å²	61.9	44%	0.436	33%	0.334	S	S	.	.	S	Bend	trans	-67.9	-23	178.4	-60.9	164.8	0	0	0	111.7	R463 V464	R463-I474 VanDerWaalsContact CZ-O 3.29Å; R463-I474 PolarHBondContact NE-O 3.48Å; R463-I474 PolarHBondContact NH2-O 3.34Å; V464-I474 HydrophobicContact CG2-CG2 3.83Å
475	Y	74.9	Confident	81.4	Confident	70 Å²	70	59.7 Å²	59.7	28%	0.275	32%	0.32	S	S	.	.			trans	-144.5	79.1	179.5	-164.6	-100	0	0	0	110.8	R463 D473 I478 V481	R463-Y475 VanDerWaalsContact CZ-CD2 3.41Å; R463-Y475 VanDerWaalsContact NH2-CD2 3.29Å; D473-Y475 PolarHBondContact O-N 3.29Å; Y475-I478 HydrophobicContact CE1-CG1 4.15Å; Y475-I478 WeakPolarHBondContact OH-CG1 3.36Å; Y475-V481 HydrophobicContact CD2-CG2 3.67Å; Y475-V481 HydrophobicContact CE2-CB 4.2Å; Y475-V481 HydrophobicContact CE2-CG1 4.33Å; Y475-V481 HydrophobicContact CE2-CG2 3.64Å
476	P	72.4	Confident	82	Confident	45 Å²	45	62.8 Å²	62.8	29%	0.292	34%	0.338	S	S	.	.	S	Bend	trans	-68.8	-45	-176.2	25.7	-32.3	0	0	0	111.7	L467 F471 H480	L467-P476 HydrophobicContact CD1-CG 4.19Å; F471-P476 HydrophobicContact CB-CB 4.12Å; F471-P476 HydrophobicContact CB-CG 4.21Å; F471-P476 HydrophobicContact CD2-CG 4.14Å; F471-P476 HydrophobicContact CG-CB 4.26Å; F471-P476 HydrophobicContact CG-CG 4.15Å; P476-H480 HydrophobicContact CG-CB 4.1Å
477	S	81.9	Confident	82.5	Confident	49 Å²	49	66.1 Å²	66.1	34%	0.343	36%	0.355	S	S	.	.			trans	-163.5	154.1	176.8	162	0	0	0	0	111.1	F479 H480 V481	S477-F479 PolarHBondContact O-N 3.27Å; S477-F479 PolarHBondContact OG-N 3.28Å; S477-H480 PolarHBondContact O-N 2.76Å; S477-V481 PolarHBondContact O-N 3.39Å
478	I	83.1	Confident	82.9	Confident	116 Å²	116	66 Å²	66	60%	0.595	35%	0.354	S	S	*	.	H	α-helix	trans	-53.7	-40.2	174.7	-64.8	158.5	0	0	0	110.7	Y475 V481 L482	Y475-I478 HydrophobicContact CE1-CG1 4.15Å; Y475-I478 WeakPolarHBondContact OH-CG1 3.36Å; I478-V481 PolarHBondContact O-N 3.23Å; I478-L482 WeakPolarHBondContact O-CB 3.34Å; I478-L482 PolarHBondContact O-N 2.87Å
479	F	87.1	Confident	83.8	Confident	133 Å²	133	65.1 Å²	65.1	58%	0.583	34%	0.344	S	S	*	.	H	α-helix	trans	-66.7	-41.8	-176.6	-173.7	-107.2	0	0	0	112.6	S477 V481 L482 I483	S477-F479 PolarHBondContact O-N 3.27Å; S477-F479 PolarHBondContact OG-N 3.28Å; F479-V481 VanDerWaalsContact C-N 3.34Å; F479-V481 PolarHBondContact O-N 3.43Å; F479-L482 PolarHBondContact O-N 3.3Å; F479-I483 HydrophobicContact CD1-CD1 3.61Å; F479-I483 HydrophobicContact CE1-CD1 3.18Å; F479-I483 HydrophobicContact CE1-CG1 4.27Å; F479-I483 HydrophobicContact CE2-CD1 4.25Å; F479-I483 HydrophobicContact CG-CD1 4.32Å; F479-I483 HydrophobicContact CZ-CD1 3.55Å; F479-I483 HydrophobicContact CZ-CG1 4.31Å; F479-I483 WeakPolarHBondContact O-CG1 3.41Å; F479-I483 PolarHBondContact O-N 3.1Å
480	H	86.8	Confident	84.5	Confident	73 Å²	73	63.8 Å²	63.8	34%	0.338	35%	0.345	S	S	.	.	H	α-helix	trans	-65.1	-40.7	177.9	-69.9	76.8	0	0	0	111.3	F471 P476 S477 L484	F471-H480 AromaticContact CE1-CD2 3.92Å; F471-H480 AromaticContact CE1-NE2 3.89Å; F471-H480 AromaticContact CE2-CD2 3.95Å; F471-H480 AromaticContact CZ-CD2 3.46Å; F471-H480 VanDerWaalsContact CZ-CD2 3.46Å; F471-H480 WeakPolarHBondContact CZ-CD2 3.5Å; F471-H480 AromaticContact CZ-NE2 3.84Å; P476-H480 HydrophobicContact CG-CB 4.1Å; S477-H480 PolarHBondContact O-N 2.76Å; H480-L484 PolarHBondContact O-N 2.84Å; H480-L484 VanDerWaalsContact O-N 3.11Å
481	V	86.9	Confident	85.1	Confident	0 Å²	0	61.2 Å²	61.2	0%	0	34%	0.337	C	S	.	.	H	α-helix	trans	-67.5	-42.1	176.5	175.1	0	0	0	0	111.2	R463 L467 Y475 S477 I478 F479 L484 N485	R463-V481 HydrophobicContact CG-CG2 4.48Å; L467-V481 HydrophobicContact CD1-CG2 3.69Å; Y475-V481 HydrophobicContact CD2-CG2 3.67Å; Y475-V481 HydrophobicContact CE2-CB 4.2Å; Y475-V481 HydrophobicContact CE2-CG1 4.33Å; Y475-V481 HydrophobicContact CE2-CG2 3.64Å; S477-V481 PolarHBondContact O-N 3.39Å; I478-V481 PolarHBondContact O-N 3.23Å; F479-V481 VanDerWaalsContact C-N 3.34Å; F479-V481 PolarHBondContact O-N 3.43Å; V481-L484 PolarHBondContact O-N 3.06Å; V481-N485 WeakPolarHBondContact O-CB 3.37Å; V481-N485 VanDerWaalsContact O-CG 3.27Å; V481-N485 PolarHBondContact O-N 3.18Å; V481-N485 PolarHBondContact O-ND2 3.17Å
482	L	89.4	Confident	85.7	Confident	75 Å²	75	56.8 Å²	56.8	39%	0.393	32%	0.317	S	S	.	.	H	α-helix	trans	-61.5	-45.5	177.3	-170.3	81.6	0	0	0	111.3	I478 F479 N485 L486	I478-L482 WeakPolarHBondContact O-CB 3.34Å; I478-L482 PolarHBondContact O-N 2.87Å; F479-L482 PolarHBondContact O-N 3.3Å; L482-N485 PolarHBondContact O-N 2.76Å; L482-L486 VanDerWaalsContact O-CB 3.29Å; L482-L486 WeakPolarHBondContact O-CB 3.46Å; L482-L486 PolarHBondContact O-N 3.36Å
483	I	91.6	Very high	86.8	Confident	70 Å²	70	54.4 Å²	54.4	36%	0.359	29%	0.29	S	S	.	.	H	α-helix	trans	-59.7	-49.1	177.1	-73.7	171.2	0	0	0	110.7	F479 N485 L486 I487	F479-I483 HydrophobicContact CD1-CD1 3.61Å; F479-I483 HydrophobicContact CE1-CD1 3.18Å; F479-I483 HydrophobicContact CE1-CG1 4.27Å; F479-I483 HydrophobicContact CE2-CD1 4.25Å; F479-I483 HydrophobicContact CG-CD1 4.32Å; F479-I483 HydrophobicContact CZ-CD1 3.55Å; F479-I483 HydrophobicContact CZ-CG1 4.31Å; F479-I483 WeakPolarHBondContact O-CG1 3.41Å; F479-I483 PolarHBondContact O-N 3.1Å; I483-N485 VanDerWaalsContact C-N 3.35Å; I483-N485 PolarHBondContact O-N 3.02Å; I483-L486 PolarHBondContact O-N 3.25Å; I483-I487 HydrophobicContact CG2-CD1 3.76Å; I483-I487 HydrophobicContact CG2-CG1 4.44Å; I483-I487 WeakPolarHBondContact O-CG1 3.48Å; I483-I487 PolarHBondContact O-N 2.97Å
484	L	90.3	Very high	87.8	Confident	18 Å²	18	54.2 Å²	54.2	9%	0.094	29%	0.288	C	S	.	.	H	α-helix	trans	-59	-48.2	179.4	177.4	60.8	0	0	0	111.4	R463 L466 L467 H480 V481 L486 I487 I488	R463-L484 HydrophobicContact CB-CD2 4.13Å; R463-L484 HydrophobicContact CG-CD2 4.19Å; L466-L484 HydrophobicContact CD2-CD1 3.35Å; L466-L484 HydrophobicContact CD2-CD2 3.95Å; L466-L484 HydrophobicContact CD2-CG 4.25Å; L467-L484 HydrophobicContact CD1-CD2 4.37Å; L467-L484 HydrophobicContact CD2-CD2 4.41Å; L467-L484 HydrophobicContact CG-CD2 4.1Å; H480-L484 PolarHBondContact O-N 2.84Å; H480-L484 VanDerWaalsContact O-N 3.11Å; V481-L484 PolarHBondContact O-N 3.06Å; L484-L486 VanDerWaalsContact C-N 3.31Å; L484-L486 PolarHBondContact O-N 2.92Å; L484-I487 PolarHBondContact O-N 2.86Å; L484-I488 HydrophobicContact CD1-CD1 3.92Å; L484-I488 HydrophobicContact CD1-CG1 4.3Å; L484-I488 HydrophobicContact CG-CD1 3.92Å; L484-I488 WeakPolarHBondContact O-CG1 3.4Å; L484-I488 PolarHBondContact O-N 2.87Å
485	N	91.4	Very high	88.9	Confident	1 Å²	1	52.8 Å²	52.8	1%	0.005	28%	0.28	C	S	.	.	H	α-helix	trans	-62.1	-38.9	178.6	-74.2	-19.9	0	0	0	111.7	L300 L303 N304 V481 L482 I483 I488 V489	L300-N485 HydrophobicContact CD1-CB 4.32Å; L303-N485 PolarHBondContact O-ND2 3Å; N304-N485 PolarHBondContact OD1-ND2 3.39Å; V481-N485 WeakPolarHBondContact O-CB 3.37Å; V481-N485 VanDerWaalsContact O-CG 3.27Å; V481-N485 PolarHBondContact O-N 3.18Å; V481-N485 PolarHBondContact O-ND2 3.17Å; L482-N485 PolarHBondContact O-N 2.76Å; I483-N485 VanDerWaalsContact C-N 3.35Å; I483-N485 PolarHBondContact O-N 3.02Å; N485-I488 PolarHBondContact O-N 2.99Å; N485-V489 WeakPolarHBondContact O-CB 3.44Å; N485-V489 VanDerWaalsContact O-CG2 3.28Å; N485-V489 WeakPolarHBondContact O-CG2 3.13Å; N485-V489 PolarHBondContact O-N 3.42Å
486	L	92.5	Very high	89.6	Confident	108 Å²	108	49.6 Å²	49.6	57%	0.565	27%	0.268	S	S	*	.	H	α-helix	trans	-65.3	-41	176.7	-171.4	72	0	0	0	111.7	L482 I483 L484 G490	L482-L486 VanDerWaalsContact O-CB 3.29Å; L482-L486 WeakPolarHBondContact O-CB 3.46Å; L482-L486 PolarHBondContact O-N 3.36Å; I483-L486 PolarHBondContact O-N 3.25Å; L484-L486 VanDerWaalsContact C-N 3.31Å; L484-L486 PolarHBondContact O-N 2.92Å; L486-G490 WeakPolarHBondContact O-CA 3.4Å; L486-G490 PolarHBondContact O-N 3.42Å
487	I	93.5	Very high	90.4	Very high	111 Å²	111	49 Å²	49	57%	0.569	27%	0.265	S	S	*	.	H	α-helix	trans	-62.7	-47.4	175.8	-69	166.7	0	0	0	110.4	I483 L484 G490 A491	I483-I487 HydrophobicContact CG2-CD1 3.76Å; I483-I487 HydrophobicContact CG2-CG1 4.44Å; I483-I487 WeakPolarHBondContact O-CG1 3.48Å; I483-I487 PolarHBondContact O-N 2.97Å; L484-I487 PolarHBondContact O-N 2.86Å; I487-G490 PolarHBondContact O-N 3.43Å; I487-A491 WeakPolarHBondContact O-CB 3.38Å; I487-A491 PolarHBondContact O-N 3.18Å
488	I	92.8	Very high	90.7	Very high	4 Å²	4	54.8 Å²	54.8	2%	0.021	28%	0.284	C	S	.	.	H	α-helix	trans	-65.2	-47.2	-178.4	-65.1	168	0	0	0	111.1	M213 A462 L484 N485 G490 A491 G492	M213-I488 HydrophobicContact CB-CG2 4.14Å; M213-I488 HydrophobicContact CE-CG2 3.42Å; M213-I488 VanDerWaalsContact CE-CG2 3.42Å; M213-I488 HydrophobicContact SD-CD1 4.48Å; M213-I488 HydrophobicContact SD-CG2 3.66Å; A462-I488 HydrophobicContact CB-CD1 4.36Å; L484-I488 HydrophobicContact CD1-CD1 3.92Å; L484-I488 HydrophobicContact CD1-CG1 4.3Å; L484-I488 HydrophobicContact CG-CD1 3.92Å; L484-I488 WeakPolarHBondContact O-CG1 3.4Å; L484-I488 PolarHBondContact O-N 2.87Å; N485-I488 PolarHBondContact O-N 2.99Å; I488-G490 VanDerWaalsContact C-N 3.35Å; I488-A491 PolarHBondContact O-N 3.46Å; I488-G492 PolarHBondContact O-N 3.36Å; I488-G492 VanDerWaalsContact O-N 3.08Å
489	V	94	Very high	90.9	Very high	4 Å²	4	54.1 Å²	54.1	2%	0.024	28%	0.275	C	S	.	.	H	α-helix	trans	-63.9	-42.2	176.9	169.8	0	0	0	0	110.8	W217 V296 L300 L303 N485 A491 G492 V493	W217-V489 HydrophobicContact CH2-CB 4.49Å; W217-V489 HydrophobicContact CH2-CG1 3.57Å; W217-V489 HydrophobicContact CH2-CG2 4.29Å; W217-V489 HydrophobicContact CZ2-CG1 3.92Å; W217-V489 HydrophobicContact CZ3-CG1 4.05Å; W217-V489 HydrophobicContact CZ3-CG2 4.04Å; V296-V489 HydrophobicContact CG1-CG1 4.23Å; V296-V489 HydrophobicContact CG2-CG1 3.85Å; L300-V489 HydrophobicContact CD1-CG2 4.15Å; L303-V489 HydrophobicContact CD1-CG2 3.51Å; N485-V489 WeakPolarHBondContact O-CB 3.44Å; N485-V489 VanDerWaalsContact O-CG2 3.28Å; N485-V489 WeakPolarHBondContact O-CG2 3.13Å; N485-V489 PolarHBondContact O-N 3.42Å; V489-A491 PolarHBondContact O-N 3.18Å; V489-G492 PolarHBondContact O-N 2.93Å; V489-G492 VanDerWaalsContact O-N 3.16Å; V489-V493 HydrophobicContact CG1-CG2 4.25Å; V489-V493 WeakPolarHBondContact O-CG2 3.48Å; V489-V493 PolarHBondContact O-N 2.85Å
490	G	93.6	Very high	90.9	Very high	26 Å²	26	51.1 Å²	51.1	27%	0.268	27%	0.269	S	S	.	.	H	α-helix	trans	-58.6	-44.7	176.2	0	0	0	0	0	112.4	L486 I487 I488 G492 V493 I494	L486-G490 WeakPolarHBondContact O-CA 3.4Å; L486-G490 PolarHBondContact O-N 3.42Å; I487-G490 PolarHBondContact O-N 3.43Å; I488-G490 VanDerWaalsContact C-N 3.35Å; G490-G492 VanDerWaalsContact C-N 3.34Å; G490-G492 PolarHBondContact O-N 3.25Å; G490-V493 PolarHBondContact O-N 3.37Å; G490-I494 WeakPolarHBondContact O-CB 3.37Å; G490-I494 VanDerWaalsContact O-CG1 3.22Å; G490-I494 WeakPolarHBondContact O-CG1 3.28Å; G490-I494 PolarHBondContact O-N 3.5Å
491	A	93.5	Very high	90.9	Very high	35 Å²	35	50 Å²	50	29%	0.289	27%	0.265	S	S	.	.	H	α-helix	trans	-60.9	-41.9	174.4	0	0	0	0	0	112.2	I214 I487 I488 V489 M495	I214-A491 HydrophobicContact CD1-CB 4.35Å; I214-A491 HydrophobicContact CG1-CB 4.48Å; I487-A491 WeakPolarHBondContact O-CB 3.38Å; I487-A491 PolarHBondContact O-N 3.18Å; I488-A491 PolarHBondContact O-N 3.46Å; V489-A491 PolarHBondContact O-N 3.18Å; A491-M495 WeakPolarHBondContact O-CB 3.46Å; A491-M495 PolarHBondContact O-N 3.2Å
492	G	92.9	Very high	90.9	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-62.3	-44.8	175.3	0	0	0	0	0	113.2	W217 I488 V489 G490 M495 A496	W217-G492 VanDerWaalsContact CD1-C 3.44Å; I488-G492 PolarHBondContact O-N 3.36Å; I488-G492 VanDerWaalsContact O-N 3.08Å; V489-G492 PolarHBondContact O-N 2.93Å; V489-G492 VanDerWaalsContact O-N 3.16Å; G490-G492 VanDerWaalsContact C-N 3.34Å; G490-G492 PolarHBondContact O-N 3.25Å; G492-M495 PolarHBondContact O-N 2.71Å; G492-A496 WeakPolarHBondContact O-CB 3.39Å; G492-A496 PolarHBondContact O-N 3.42Å
493	V	93.6	Very high	90.8	Very high	13 Å²	13	46.7 Å²	46.7	8%	0.079	25%	0.248	C	C	.	.	H	α-helix	trans	-64.7	-49.2	177.5	173.7	0	0	0	0	110.9	W217 P292 F293 V296 V489 G490 M495 A496 C497	W217-V493 HydrophobicContact CZ2-CG2 3.74Å; P292-V493 HydrophobicContact CB-CG1 4.49Å; F293-V493 HydrophobicContact CD1-CG1 4.27Å; F293-V493 HydrophobicContact CD2-CG1 4.45Å; F293-V493 HydrophobicContact CE1-CG1 3.82Å; F293-V493 HydrophobicContact CE2-CG1 4.04Å; F293-V493 HydrophobicContact CZ-CG1 3.7Å; V296-V493 HydrophobicContact CG2-CG2 3.76Å; V489-V493 HydrophobicContact CG1-CG2 4.25Å; V489-V493 WeakPolarHBondContact O-CG2 3.48Å; V489-V493 PolarHBondContact O-N 2.85Å; G490-V493 PolarHBondContact O-N 3.37Å; V493-M495 VanDerWaalsContact C-N 3.26Å; V493-M495 PolarHBondContact O-N 2.9Å; V493-A496 PolarHBondContact O-N 3.23Å; V493-C497 PolarHBondContact O-N 2.81Å; V493-C497 PolarHBondContact O-SG 2.95Å
494	I	93.5	Very high	90.6	Very high	103 Å²	103	43.5 Å²	43.5	53%	0.528	23%	0.232	S	C	.	.	H	α-helix	trans	-55.3	-46.6	178.1	-70.9	166.8	0	0	0	109.8	G490 C497 F498	G490-I494 WeakPolarHBondContact O-CB 3.37Å; G490-I494 VanDerWaalsContact O-CG1 3.22Å; G490-I494 WeakPolarHBondContact O-CG1 3.28Å; G490-I494 PolarHBondContact O-N 3.5Å; I494-C497 PolarHBondContact O-N 3.2Å; I494-F498 HydrophobicContact CG2-CD2 3.96Å; I494-F498 VanDerWaalsContact O-CD2 3.31Å; I494-F498 WeakPolarHBondContact O-CD2 3.22Å; I494-F498 PolarHBondContact O-N 2.62Å
495	M	91.6	Very high	90.7	Very high	54 Å²	54	43.4 Å²	43.4	27%	0.266	23%	0.232	S	C	.	.	H	α-helix	trans	-67.1	-40.7	-179	-157.8	62.2	168.8	0	0	112.6	I214 A491 G492 V493 C497 Y499 I505	I214-M495 HydrophobicContact CG2-CB 3.58Å; I214-M495 HydrophobicContact CG2-CG 3.61Å; A491-M495 WeakPolarHBondContact O-CB 3.46Å; A491-M495 PolarHBondContact O-N 3.2Å; G492-M495 PolarHBondContact O-N 2.71Å; V493-M495 VanDerWaalsContact C-N 3.26Å; V493-M495 PolarHBondContact O-N 2.9Å; M495-C497 VanDerWaalsContact C-N 3.28Å; M495-C497 PolarHBondContact O-N 3.49Å; M495-Y499 HydrophobicContact CE-CD1 3.25Å; M495-Y499 HydrophobicContact CE-CE1 4.05Å; M495-Y499 HydrophobicContact CE-CG 3.95Å; M495-Y499 CarbonylContact O-C 3.01Å; M495-Y499 WeakPolarHBondContact O-CA 3.44Å; M495-Y499 PolarHBondContact O-N 2.97Å; M495-Y499 VanDerWaalsContact O-O 3.1Å; M495-Y499 HydrophobicContact SD-CD1 4.33Å; M495-I505 HydrophobicContact CE-CD1 3.91Å; M495-I505 HydrophobicContact CE-CG1 3.53Å; M495-I505 HydrophobicContact CG-CD1 3.69Å; M495-I505 HydrophobicContact CG-CG1 4.29Å
496	A	89.3	Confident	90.6	Very high	3 Å²	3	43.5 Å²	43.5	3%	0.025	23%	0.232	C	C	.	.	H	α-helix	trans	-63.7	-32.6	176.2	0	0	0	0	0	113.1	V218 P292 G492 V493	V218-A496 HydrophobicContact CG2-CB 4.11Å; P292-A496 HydrophobicContact CB-CB 4.09Å; P292-A496 HydrophobicContact CG-CB 3.97Å; G492-A496 WeakPolarHBondContact O-CB 3.39Å; G492-A496 PolarHBondContact O-N 3.42Å; V493-A496 PolarHBondContact O-N 3.23Å
497	C	88.3	Confident	90.6	Very high	32 Å²	32	39.5 Å²	39.5	22%	0.216	21%	0.209	C	C	.	.	H	α-helix	trans	-79.3	-44.9	178.8	-62.2	0	0	0	0	113.1	S288 V493 I494 M495	S288-C497 VanDerWaalsContact O-CA 3.31Å; S288-C497 WeakPolarHBondContact O-CA 3.45Å; S288-C497 WeakPolarHBondContact O-CB 3.31Å; S288-C497 PolarHBondContact O-SG 3.5Å; V493-C497 PolarHBondContact O-N 2.81Å; V493-C497 PolarHBondContact O-SG 2.95Å; I494-C497 PolarHBondContact O-N 3.2Å; M495-C497 VanDerWaalsContact C-N 3.28Å; M495-C497 PolarHBondContact O-N 3.49Å
498	F	89.3	Confident	90.6	Very high	172 Å²	172	37.9 Å²	37.9	75%	0.754	20%	0.197	S	C	*	.	H	α-helix	trans	-99.7	-30.2	-169.5	-69.2	-76.3	0	0	0	114.3	I494	I494-F498 HydrophobicContact CG2-CD2 3.96Å; I494-F498 VanDerWaalsContact O-CD2 3.31Å; I494-F498 WeakPolarHBondContact O-CD2 3.22Å; I494-F498 PolarHBondContact O-N 2.62Å
499	Y	88.1	Confident	90.5	Very high	102 Å²	102	38.2 Å²	38.2	40%	0.4	20%	0.2	S	C	.	.			trans	-147.1	72.5	-176.8	-167.9	-93.9	0	0	0	111.5	M495 N501	M495-Y499 HydrophobicContact CE-CD1 3.25Å; M495-Y499 HydrophobicContact CE-CE1 4.05Å; M495-Y499 HydrophobicContact CE-CG 3.95Å; M495-Y499 CarbonylContact O-C 3.01Å; M495-Y499 WeakPolarHBondContact O-CA 3.44Å; M495-Y499 PolarHBondContact O-N 2.97Å; M495-Y499 VanDerWaalsContact O-O 3.1Å; M495-Y499 HydrophobicContact SD-CD1 4.33Å; Y499-N501 HydrophobicContact CD1-CB 3.87Å; Y499-N501 HydrophobicContact CE1-CB 3.52Å; Y499-N501 HydrophobicContact CE2-CB 4.42Å; Y499-N501 PolarHBondContact O-N 3.22Å
500	P	85.6	Confident	90.4	Very high	69 Å²	69	38 Å²	38	45%	0.448	20%	0.198	S	C	.	.			trans	-78.6	42.1	-178.6	33.9	-37.1	0	0	0	113.2	V218	V218-P500 HydrophobicContact CG1-CB 4.06Å
501	N	87.1	Confident	90.4	Very high	49 Å²	49	36.8 Å²	36.8	26%	0.262	19%	0.186	S	C	.	.			trans	-97.5	95.6	179.7	-179.2	-29.4	0	0	0	109.8	Q427 Y499 G504 I505	Q427-N501 VanDerWaalsContact NE2-CG 3.31Å; Q427-N501 PolarHBondContact NE2-OD1 3.08Å; Q427-N501 PolarHBondContact OE1-OD1 3.35Å; Y499-N501 HydrophobicContact CD1-CB 3.87Å; Y499-N501 HydrophobicContact CE1-CB 3.52Å; Y499-N501 HydrophobicContact CE2-CB 4.42Å; Y499-N501 PolarHBondContact O-N 3.22Å; N501-G504 PolarHBondContact O-N 3.47Å; N501-G504 WeakPolarHBondContact OD1-CA 3.29Å; N501-G504 PolarHBondContact OD1-N 3.39Å; N501-I505 WeakPolarHBondContact O-CD1 3.43Å; N501-I505 VanDerWaalsContact O-CG1 3.29Å; N501-I505 WeakPolarHBondContact O-CG1 3.31Å; N501-I505 PolarHBondContact O-N 3.43Å; N501-I505 VanDerWaalsContact O-N 3.11Å
502	I	87.4	Confident	90.4	Very high	6 Å²	6	36.3 Å²	36.3	3%	0.031	18%	0.181	C	C	.	.	H	α-helix	trans	-60.7	-49.7	-174.5	-63.6	152.9	0	0	0	111.3	V215 V218 L219 N428 G504 I505 I506	V215-I502 HydrophobicContact CG1-CG2 4.25Å; V218-I502 HydrophobicContact CG1-CD1 4.38Å; V218-I502 HydrophobicContact CG1-CG1 3.75Å; L219-I502 HydrophobicContact CD1-CG2 4.34Å; L219-I502 HydrophobicContact CD2-CD1 3.45Å; L219-I502 VanDerWaalsContact CD2-CD1 3.45Å; L219-I502 HydrophobicContact CD2-CG1 4.22Å; L219-I502 HydrophobicContact CG-CD1 4Å; L219-I502 HydrophobicContact CG-CG1 4.24Å; L219-I502 HydrophobicContact CG-CG2 4.48Å; N428-I502 HydrophobicContact CB-CD1 4.1Å; I502-G504 VanDerWaalsContact C-N 3.31Å; I502-G504 PolarHBondContact O-N 3.31Å; I502-I505 PolarHBondContact O-N 3.48Å; I502-I506 HydrophobicContact CG2-CD1 3.56Å; I502-I506 HydrophobicContact CG2-CG1 4.29Å; I502-I506 WeakPolarHBondContact O-CB 3.46Å; I502-I506 VanDerWaalsContact O-CG1 3.23Å; I502-I506 WeakPolarHBondContact O-CG1 3.36Å; I502-I506 PolarHBondContact O-N 2.9Å
503	G	86.3	Confident	90.2	Very high	0 Å²	0	36.3 Å²	36.3	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-61.7	-38.5	-179.9	0	0	0	0	0	112.4	R507	G503-R507 WeakPolarHBondContact O-CB 3.34Å; G503-R507 WeakPolarHBondContact O-CG 3.38Å; G503-R507 PolarHBondContact O-N 2.95Å
504	G	88.9	Confident	90.1	Very high	3 Å²	3	35.7 Å²	35.7	3%	0.031	18%	0.178	C	C	.	.	H	α-helix	trans	-62.5	-46.1	173.9	0	0	0	0	0	112.7	N501 I502 R507 Y508	N501-G504 PolarHBondContact O-N 3.47Å; N501-G504 WeakPolarHBondContact OD1-CA 3.29Å; N501-G504 PolarHBondContact OD1-N 3.39Å; I502-G504 VanDerWaalsContact C-N 3.31Å; I502-G504 PolarHBondContact O-N 3.31Å; G504-R507 VanDerWaalsContact O-CG 3.3Å; G504-R507 WeakPolarHBondContact O-CG 3.39Å; G504-Y508 WeakPolarHBondContact O-CD2 3.39Å; G504-Y508 PolarHBondContact O-N 2.84Å
505	I	91.1	Very high	90.1	Very high	16 Å²	16	31.9 Å²	31.9	8%	0.082	16%	0.158	C	C	.	.	H	α-helix	trans	-66	-46.4	178.8	-60	157.1	0	0	0	110.3	I214 V215 V218 M495 N501 I502 S509	I214-I505 HydrophobicContact CG2-CD1 4.14Å; I214-I505 HydrophobicContact CG2-CG2 4.26Å; V215-I505 HydrophobicContact CG2-CB 3.92Å; V215-I505 HydrophobicContact CG2-CG2 3.46Å; V215-I505 VanDerWaalsContact CG2-CG2 3.46Å; V218-I505 HydrophobicContact CG2-CD1 4.15Å; M495-I505 HydrophobicContact CE-CD1 3.91Å; M495-I505 HydrophobicContact CE-CG1 3.53Å; M495-I505 HydrophobicContact CG-CD1 3.69Å; M495-I505 HydrophobicContact CG-CG1 4.29Å; N501-I505 WeakPolarHBondContact O-CD1 3.43Å; N501-I505 VanDerWaalsContact O-CG1 3.29Å; N501-I505 WeakPolarHBondContact O-CG1 3.31Å; N501-I505 PolarHBondContact O-N 3.43Å; N501-I505 VanDerWaalsContact O-N 3.11Å; I502-I505 PolarHBondContact O-N 3.48Å; I505-S509 WeakPolarHBondContact O-CB 3.38Å; I505-S509 PolarHBondContact O-N 3.04Å
506	I	90.9	Very high	90	Very high	3 Å²	3	29.4 Å²	29.4	2%	0.015	15%	0.146	C	C	.	.	H	α-helix	trans	-62.5	-45.3	-179.4	-65.7	173.7	0	0	0	110.7	V215 V365 L368 I502 Y508 G510	V215-I506 HydrophobicContact CG1-CD1 4.05Å; V215-I506 HydrophobicContact CG1-CG1 4.03Å; V215-I506 HydrophobicContact CG2-CG1 3.68Å; V365-I506 HydrophobicContact CB-CG2 4.16Å; V365-I506 HydrophobicContact CG1-CG2 4.05Å; V365-I506 HydrophobicContact CG2-CB 4.49Å; V365-I506 HydrophobicContact CG2-CG2 4Å; L368-I506 HydrophobicContact CB-CG2 4.07Å; L368-I506 HydrophobicContact CD2-CB 4.26Å; L368-I506 HydrophobicContact CD2-CG1 4.32Å; L368-I506 HydrophobicContact CD2-CG2 3.81Å; I502-I506 HydrophobicContact CG2-CD1 3.56Å; I502-I506 HydrophobicContact CG2-CG1 4.29Å; I502-I506 WeakPolarHBondContact O-CB 3.46Å; I502-I506 VanDerWaalsContact O-CG1 3.23Å; I502-I506 WeakPolarHBondContact O-CG1 3.36Å; I502-I506 PolarHBondContact O-N 2.9Å; I506-Y508 PolarHBondContact O-N 3.42Å; I506-G510 WeakPolarHBondContact O-CA 3.28Å; I506-G510 PolarHBondContact O-N 3.31Å
507	R	92.3	Very high	90	Very high	24 Å²	24	29.2 Å²	29.2	9%	0.091	15%	0.145	C	C	.	.	H	α-helix	trans	-62.8	-45.3	-177.6	75.8	-178.9	-171.8	165.3	14	112.2	V365 G503 G504 A511 M561	V365-R507 HydrophobicContact CG2-CB 4.24Å; G503-R507 WeakPolarHBondContact O-CB 3.34Å; G503-R507 WeakPolarHBondContact O-CG 3.38Å; G503-R507 PolarHBondContact O-N 2.95Å; G504-R507 VanDerWaalsContact O-CG 3.3Å; G504-R507 WeakPolarHBondContact O-CG 3.39Å; R507-A511 VanDerWaalsContact O-CB 3.23Å; R507-A511 WeakPolarHBondContact O-CB 3.11Å; R507-A511 PolarHBondContact O-N 3.21Å; R507-M561 PolarHBondContact NH1-OXT 3.34Å; R507-M561 PolarHBondContact NH2-OXT 3.12Å
508	Y	92.6	Very high	90.1	Very high	78 Å²	78	27.7 Å²	27.7	31%	0.306	14%	0.135	S	C	.	.	H	α-helix	trans	-73.9	-45	-178.3	-72.3	-59.3	0	0	0	111.7	G504 I506 G510 A511 A512 Q558 F559	G504-Y508 WeakPolarHBondContact O-CD2 3.39Å; G504-Y508 PolarHBondContact O-N 2.84Å; I506-Y508 PolarHBondContact O-N 3.42Å; Y508-G510 VanDerWaalsContact C-N 3.33Å; Y508-G510 PolarHBondContact O-N 2.92Å; Y508-A511 PolarHBondContact O-N 2.95Å; Y508-A512 VanDerWaalsContact O-CB 3.26Å; Y508-A512 WeakPolarHBondContact O-CB 3.4Å; Y508-A512 PolarHBondContact O-N 3.34Å; Y508-Q558 HydrophobicContact CD1-CB 3.91Å; Y508-Q558 HydrophobicContact CE1-CB 3.72Å; Y508-Q558 PolarHBondContact OH-O 3.13Å; Y508-F559 HydrophobicContact CE1-CD1 4.23Å; Y508-F559 HydrophobicContact CE1-CE1 4.19Å
509	S	91.7	Very high	90.3	Very high	11 Å²	11	19.7 Å²	19.7	8%	0.077	10%	0.1	C	C	.	.	H	α-helix	trans	-59.8	-46.3	176.5	-175.3	0	0	0	0	110.8	I505 A512 C513	I505-S509 WeakPolarHBondContact O-CB 3.38Å; I505-S509 PolarHBondContact O-N 3.04Å; S509-A512 PolarHBondContact O-N 2.92Å; S509-C513 PolarHBondContact O-N 3.18Å; S509-C513 PolarHBondContact O-SG 3.28Å
510	G	91.4	Very high	90.6	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-64	-45.5	178.8	0	0	0	0	0	113.4	T367 I506 Y508 G514	T367-G510 VanDerWaalsContact CG2-O 3.23Å; T367-G510 WeakPolarHBondContact CG2-O 3.35Å; I506-G510 WeakPolarHBondContact O-CA 3.28Å; I506-G510 PolarHBondContact O-N 3.31Å; Y508-G510 VanDerWaalsContact C-N 3.33Å; Y508-G510 PolarHBondContact O-N 2.92Å; G510-G514 WeakPolarHBondContact O-CA 3.39Å; G510-G514 PolarHBondContact O-N 3.07Å
511	A	93.4	Very high	90.9	Very high	0 Å²	0	14 Å²	14	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-65.1	-40.8	177.6	0	0	0	0	0	112	R507 Y508 L515 L555 Q558	R507-A511 VanDerWaalsContact O-CB 3.23Å; R507-A511 WeakPolarHBondContact O-CB 3.11Å; R507-A511 PolarHBondContact O-N 3.21Å; Y508-A511 PolarHBondContact O-N 2.95Å; A511-L515 WeakPolarHBondContact O-CB 3.29Å; A511-L515 PolarHBondContact O-N 2.84Å; A511-L555 HydrophobicContact CB-CB 4.48Å; A511-L555 HydrophobicContact CB-CD1 3.94Å; A511-Q558 HydrophobicContact CB-CG 3.76Å
512	A	92.8	Very high	91.2	Very high	24 Å²	24	11.8 Å²	11.8	20%	0.198	6%	0.06	C	C	.	.	H	α-helix	trans	-69.4	-48.9	-179.9	0	0	0	0	0	112.7	F204 V207 Y508 S509 L555	F204-A512 WeakPolarHBondContact CD1-O 3.46Å; V207-A512 HydrophobicContact CG1-CB 4.41Å; Y508-A512 VanDerWaalsContact O-CB 3.26Å; Y508-A512 WeakPolarHBondContact O-CB 3.4Å; Y508-A512 PolarHBondContact O-N 3.34Å; S509-A512 PolarHBondContact O-N 2.92Å; A512-L555 HydrophobicContact CB-CD1 4.34Å
513	C	90.1	Very high	91.4	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-71.9	-35.7	178.7	71.3	0	0	0	0	112.1	S208 S509 A516 F517	S208-C513 PolarHBondContact OG-SG 3.2Å; S509-C513 PolarHBondContact O-N 3.18Å; S509-C513 PolarHBondContact O-SG 3.28Å; C513-A516 PolarHBondContact O-N 3.34Å; C513-F517 PolarHBondContact O-N 3.31Å
514	G	90	Very high	91.8	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-64.3	-38.3	178.1	0	0	0	0	0	113.4	G510 A516 V518 F519	G510-G514 WeakPolarHBondContact O-CA 3.39Å; G510-G514 PolarHBondContact O-N 3.07Å; G514-A516 PolarHBondContact O-N 3.14Å; G514-V518 WeakPolarHBondContact O-CA 3.21Å; G514-V518 VanDerWaalsContact O-CB 3.25Å; G514-V518 WeakPolarHBondContact O-CB 3.27Å; G514-V518 PolarHBondContact O-N 3.03Å; G514-F519 WeakPolarHBondContact O-CD2 3.29Å; G514-F519 PolarHBondContact O-N 2.99Å
515	L	93.8	Very high	91.9	Very high	23 Å²	23	14.3 Å²	14.3	12%	0.12	7%	0.072	C	C	.	.	I	π-helix	trans	-47.7	-51.6	173.5	176.1	63.2	0	0	0	111	A511 I520 G551 V552 L555	A511-L515 WeakPolarHBondContact O-CB 3.29Å; A511-L515 PolarHBondContact O-N 2.84Å; L515-I520 HydrophobicContact CD1-CD1 3.6Å; L515-I520 HydrophobicContact CD1-CG1 4.12Å; L515-I520 HydrophobicContact CD2-CD1 4.49Å; L515-I520 HydrophobicContact CG-CD1 3.76Å; L515-I520 VanDerWaalsContact O-CB 3.28Å; L515-I520 WeakPolarHBondContact O-CB 3.49Å; L515-I520 WeakPolarHBondContact O-CG1 3.44Å; L515-I520 PolarHBondContact O-N 2.85Å; L515-G551 VanDerWaalsContact CD1-C 3.48Å; L515-V552 HydrophobicContact CD1-CB 4.37Å; L515-V552 HydrophobicContact CD1-CG2 3.74Å; L515-L555 HydrophobicContact CD2-CD2 3.64Å
516	A	90.3	Very high	91.9	Very high	2 Å²	2	15 Å²	15	2%	0.017	7%	0.074	C	C	.	.	I	π-helix	trans	-78.2	-61.2	-177.3	0	0	0	0	0	112.5	F204 C513 G514 I520 Y521	F204-A516 HydrophobicContact CB-CB 3.71Å; F204-A516 HydrophobicContact CD1-CB 3.85Å; F204-A516 HydrophobicContact CD2-CB 3.3Å; F204-A516 HydrophobicContact CE1-CB 4.28Å; F204-A516 HydrophobicContact CE2-CB 3.81Å; F204-A516 HydrophobicContact CG-CB 3.34Å; F204-A516 HydrophobicContact CZ-CB 4.27Å; C513-A516 PolarHBondContact O-N 3.34Å; G514-A516 PolarHBondContact O-N 3.14Å; A516-I520 PolarHBondContact O-N 2.73Å; A516-Y521 HydrophobicContact CB-CD2 4.11Å; A516-Y521 HydrophobicContact CB-CE2 3.7Å; A516-Y521 WeakPolarHBondContact O-CB 3.33Å; A516-Y521 WeakPolarHBondContact O-CD2 3.32Å; A516-Y521 PolarHBondContact O-N 3.25Å
517	F	87.9	Confident	92	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.079	C	C	.	.	I	π-helix	trans	-81.4	-26.9	-167.9	-84.2	-84.6	0	0	0	114.9	Y185 S201 F204 S205 F371 N374 C513 Y521 P522	Y185-F517 AromaticContact CD1-CD1 3.46Å; Y185-F517 HydrophobicContact CD1-CD1 3.46Å; Y185-F517 VanDerWaalsContact CD1-CD1 3.46Å; Y185-F517 AromaticContact CD1-CE1 3.48Å; Y185-F517 HydrophobicContact CD1-CE1 3.48Å; Y185-F517 VanDerWaalsContact CD1-CE1 3.48Å; Y185-F517 AromaticContact CE1-CD1 3.41Å; Y185-F517 HydrophobicContact CE1-CD1 3.41Å; Y185-F517 VanDerWaalsContact CE1-CD1 3.41Å; Y185-F517 AromaticContact CE1-CE1 3.75Å; Y185-F517 HydrophobicContact CE1-CE1 3.75Å; S201-F517 WeakPolarHBondContact O-CE2 3.42Å; S201-F517 WeakPolarHBondContact O-CZ 3.34Å; F204-F517 HydrophobicContact CB-CD2 3.81Å; F204-F517 HydrophobicContact CB-CE2 3.64Å; S205-F517 VanDerWaalsContact N-CE2 3.31Å; F371-F517 HydrophobicContact CE2-CB 3.91Å; F371-F517 HydrophobicContact CZ-CB 4.4Å; N374-F517 WeakPolarHBondContact OD1-CD1 3.25Å; N374-F517 VanDerWaalsContact OD1-CE1 3.31Å; N374-F517 WeakPolarHBondContact OD1-CE1 3.46Å; N374-F517 WeakPolarHBondContact OD1-CG 3.37Å; C513-F517 PolarHBondContact O-N 3.31Å; F517-Y521 HydrophobicContact CD1-CD2 4.43Å; F517-Y521 HydrophobicContact CE2-CE2 4.4Å; F517-Y521 HydrophobicContact CG-CD2 4.43Å; F517-P522 WeakPolarHBondContact O-CD 3.49Å; F517-P522 WeakPolarHBondContact O-CG 3.14Å
518	V	91.3	Very high	91.9	Very high	0 Å²	0	17.2 Å²	17.2	0%	0	9%	0.087	C	C	.	.	I	π-helix	trans	-94.9	-46.4	-179	-178.9	0	0	0	0	109.8	T161 C164 T367 F371 G514 P522	T161-V518 HydrophobicContact CG2-CG1 3.99Å; C164-V518 HydrophobicContact CB-CG1 4.07Å; C164-V518 WeakPolarHBondContact CB-O 3.41Å; C164-V518 PolarHBondContact SG-O 2.75Å; T367-V518 HydrophobicContact CG2-CG2 4.36Å; F371-V518 HydrophobicContact CD2-CG2 4.08Å; F371-V518 HydrophobicContact CE2-CG2 4.39Å; G514-V518 WeakPolarHBondContact O-CA 3.21Å; G514-V518 VanDerWaalsContact O-CB 3.25Å; G514-V518 WeakPolarHBondContact O-CB 3.27Å; G514-V518 PolarHBondContact O-N 3.03Å; V518-P522 WeakPolarHBondContact O-CG 3.08Å
519	F	93.9	Very high	91.7	Very high	3 Å²	3	13.7 Å²	13.7	1%	0.013	7%	0.074	C	C	.	.	I	π-helix	trans	-100	-55.3	-170.5	-56.1	-62.3	0	0	0	113.9	M157 L160 T367 G514 S523 I547	M157-F519 HydrophobicContact CE-CZ 4.17Å; L160-F519 HydrophobicContact CD2-CD1 4.4Å; L160-F519 HydrophobicContact CD2-CE1 3.57Å; L160-F519 HydrophobicContact CD2-CZ 4.39Å; L160-F519 HydrophobicContact CG-CE1 3.98Å; T367-F519 HydrophobicContact CG2-CE2 4.07Å; T367-F519 HydrophobicContact CG2-CZ 4.48Å; G514-F519 WeakPolarHBondContact O-CD2 3.29Å; G514-F519 PolarHBondContact O-N 2.99Å; F519-S523 WeakPolarHBondContact O-CB 3.4Å; F519-S523 PolarHBondContact O-OG 3.46Å; F519-I547 HydrophobicContact CB-CG2 4.32Å; F519-I547 HydrophobicContact CD1-CG2 3.85Å
520	I	94	Very high	91.6	Very high	40 Å²	40	13.4 Å²	13.4	21%	0.205	7%	0.072	C	C	.	.	I	π-helix	trans	-73.9	-61.5	-171	-71.2	176.6	0	0	0	112.5	L515 A516 S523 L524 I548	L515-I520 HydrophobicContact CD1-CD1 3.6Å; L515-I520 HydrophobicContact CD1-CG1 4.12Å; L515-I520 HydrophobicContact CD2-CD1 4.49Å; L515-I520 HydrophobicContact CG-CD1 3.76Å; L515-I520 VanDerWaalsContact O-CB 3.28Å; L515-I520 WeakPolarHBondContact O-CB 3.49Å; L515-I520 WeakPolarHBondContact O-CG1 3.44Å; L515-I520 PolarHBondContact O-N 2.85Å; A516-I520 PolarHBondContact O-N 2.73Å; I520-S523 PolarHBondContact O-N 2.77Å; I520-L524 HydrophobicContact CG2-CD1 3.46Å; I520-L524 VanDerWaalsContact CG2-CD1 3.46Å; I520-L524 HydrophobicContact CG2-CG 4.09Å; I520-L524 WeakPolarHBondContact O-CB 3.2Å; I520-L524 WeakPolarHBondContact O-CG 3.37Å; I520-L524 PolarHBondContact O-N 3.13Å; I520-I548 HydrophobicContact CG1-CG2 4.12Å
521	Y	92	Very high	91.5	Very high	11 Å²	11	19.6 Å²	19.6	4%	0.043	10%	0.1	C	C	.	.	H	α-helix	trans	-61.1	-47.3	-170.9	-67.1	-47.6	0	0	0	113.4	Y185 F193 S200 S201 A516 F517 S523 L524 I525	Y185-Y521 WeakPolarHBondContact OH-CB 3.26Å; F193-Y521 HydrophobicContact CD2-CD1 4.36Å; F193-Y521 AromaticContact CE2-CD1 3.82Å; F193-Y521 HydrophobicContact CE2-CD1 3.82Å; F193-Y521 HydrophobicContact CE2-CE1 4.39Å; F193-Y521 HydrophobicContact CZ-CD1 4.36Å; S200-Y521 WeakPolarHBondContact CB-OH 3.05Å; S200-Y521 PolarHBondContact OG-OH 3.24Å; S201-Y521 PolarHBondContact N-OH 3.2Å; S201-Y521 VanDerWaalsContact N-OH 3.1Å; A516-Y521 HydrophobicContact CB-CD2 4.11Å; A516-Y521 HydrophobicContact CB-CE2 3.7Å; A516-Y521 WeakPolarHBondContact O-CB 3.33Å; A516-Y521 WeakPolarHBondContact O-CD2 3.32Å; A516-Y521 PolarHBondContact O-N 3.25Å; F517-Y521 HydrophobicContact CD1-CD2 4.43Å; F517-Y521 HydrophobicContact CE2-CE2 4.4Å; F517-Y521 HydrophobicContact CG-CD2 4.43Å; Y521-S523 VanDerWaalsContact C-N 3.27Å; Y521-S523 PolarHBondContact O-N 3.27Å; Y521-L524 PolarHBondContact O-N 3.22Å; Y521-I525 VanDerWaalsContact O-CB 3.31Å; Y521-I525 WeakPolarHBondContact O-CB 3.39Å; Y521-I525 WeakPolarHBondContact O-CD1 3.22Å; Y521-I525 WeakPolarHBondContact O-CG1 3.21Å; Y521-I525 PolarHBondContact O-N 3.31Å
522	P	92.3	Very high	91.1	Very high	4 Å²	4	26.1 Å²	26.1	3%	0.026	13%	0.13	C	C	.	.	H	α-helix	trans	-63.2	-36.9	-179.3	-20.3	33.6	0	0	0	112	R167 V168 F517 V518 Y526	R167-P522 HydrophobicContact CB-CB 3.88Å; V168-P522 HydrophobicContact CG2-CB 4.04Å; V168-P522 HydrophobicContact CG2-CG 3.59Å; F517-P522 WeakPolarHBondContact O-CD 3.49Å; F517-P522 WeakPolarHBondContact O-CG 3.14Å; V518-P522 WeakPolarHBondContact O-CG 3.08Å; P522-Y526 WeakPolarHBondContact O-CB 3.03Å; P522-Y526 PolarHBondContact O-N 3.46Å
523	S	93.2	Very high	90.9	Very high	2 Å²	2	28.7 Å²	28.7	1%	0.014	14%	0.138	C	C	.	.	H	α-helix	trans	-70.9	-47	179.7	-59.7	0	0	0	0	111.9	F519 I520 Y521 Y526 I527	F519-S523 WeakPolarHBondContact O-CB 3.4Å; F519-S523 PolarHBondContact O-OG 3.46Å; I520-S523 PolarHBondContact O-N 2.77Å; Y521-S523 VanDerWaalsContact C-N 3.27Å; Y521-S523 PolarHBondContact O-N 3.27Å; S523-Y526 PolarHBondContact O-N 3.21Å; S523-I527 VanDerWaalsContact O-CG1 3.3Å; S523-I527 WeakPolarHBondContact O-CG1 3.25Å; S523-I527 PolarHBondContact O-N 3.2Å
524	L	92.9	Very high	90.7	Very high	56 Å²	56	37.4 Å²	37.4	29%	0.293	18%	0.179	S	C	.	.	H	α-helix	trans	-66.1	-45.4	179.2	-73.9	-178.4	0	0	0	112.1	F193 I520 Y521 Y526 I527 I528 I548	F193-L524 HydrophobicContact CE1-CB 4.14Å; F193-L524 HydrophobicContact CE1-CD1 4.08Å; F193-L524 HydrophobicContact CZ-CB 3.65Å; F193-L524 HydrophobicContact CZ-CD1 4.09Å; I520-L524 HydrophobicContact CG2-CD1 3.46Å; I520-L524 VanDerWaalsContact CG2-CD1 3.46Å; I520-L524 HydrophobicContact CG2-CG 4.09Å; I520-L524 WeakPolarHBondContact O-CB 3.2Å; I520-L524 WeakPolarHBondContact O-CG 3.37Å; I520-L524 PolarHBondContact O-N 3.13Å; Y521-L524 PolarHBondContact O-N 3.22Å; L524-Y526 PolarHBondContact O-N 3.35Å; L524-I527 PolarHBondContact O-N 3.02Å; L524-I528 WeakPolarHBondContact O-CB 3.09Å; L524-I528 VanDerWaalsContact O-CG1 3.27Å; L524-I528 WeakPolarHBondContact O-CG1 3.37Å; L524-I528 PolarHBondContact O-N 3.05Å; L524-I548 HydrophobicContact CD2-CD1 3.89Å; L524-I548 HydrophobicContact CG-CD1 4.11Å
525	I	91.1	Very high	90.6	Very high	4 Å²	4	45 Å²	45	2%	0.021	21%	0.208	C	C	.	.	H	α-helix	trans	-56.6	-42.5	177.1	-71	167	0	0	0	110	Y185 V188 Y192 F193 Y521 S529	Y185-I525 HydrophobicContact CE2-CD1 4.07Å; V188-I525 HydrophobicContact CG1-CD1 4.27Å; Y192-I525 HydrophobicContact CD2-CB 4.46Å; Y192-I525 HydrophobicContact CD2-CG1 4.05Å; Y192-I525 HydrophobicContact CD2-CG2 3.77Å; Y192-I525 HydrophobicContact CE1-CG2 4.45Å; Y192-I525 HydrophobicContact CE2-CG2 3.52Å; Y192-I525 HydrophobicContact CG-CG1 4.26Å; Y192-I525 HydrophobicContact CG-CG2 4.32Å; F193-I525 HydrophobicContact CE2-CD1 4.25Å; F193-I525 HydrophobicContact CE2-CG1 3.71Å; F193-I525 HydrophobicContact CZ-CG1 4.11Å; Y521-I525 VanDerWaalsContact O-CB 3.31Å; Y521-I525 WeakPolarHBondContact O-CB 3.39Å; Y521-I525 WeakPolarHBondContact O-CD1 3.22Å; Y521-I525 WeakPolarHBondContact O-CG1 3.21Å; Y521-I525 PolarHBondContact O-N 3.31Å; I525-S529 VanDerWaalsContact O-CB 3.27Å; I525-S529 WeakPolarHBondContact O-CB 3.33Å; I525-S529 PolarHBondContact O-N 3Å
526	Y	91.7	Very high	90.4	Very high	30 Å²	30	46.6 Å²	46.6	12%	0.118	22%	0.216	C	C	.	.	H	α-helix	trans	-68.1	-41.2	178.5	-176.3	-115.6	0	0	0	113.4	R167 M174 P522 S523 L524 L530 H544	R167-Y526 VanDerWaalsContact NH1-CD2 3.34Å; M174-Y526 HydrophobicContact CE-CD2 4.28Å; M174-Y526 HydrophobicContact CE-CE2 3.95Å; P522-Y526 WeakPolarHBondContact O-CB 3.03Å; P522-Y526 PolarHBondContact O-N 3.46Å; S523-Y526 PolarHBondContact O-N 3.21Å; L524-Y526 PolarHBondContact O-N 3.35Å; Y526-L530 HydrophobicContact CD1-CD1 3.94Å; Y526-L530 HydrophobicContact CD2-CG 4.39Å; Y526-L530 HydrophobicContact CE1-CD1 3.36Å; Y526-L530 HydrophobicContact CE1-CG 4.21Å; Y526-L530 HydrophobicContact CE2-CD1 3.95Å; Y526-L530 HydrophobicContact CE2-CD2 4.3Å; Y526-L530 HydrophobicContact CE2-CG 3.89Å; Y526-L530 WeakPolarHBondContact O-CB 3.34Å; Y526-L530 WeakPolarHBondContact O-CG 3.36Å; Y526-L530 PolarHBondContact O-N 3.32Å; Y526-H544 AromaticContact CD1-CD2 3.79Å; Y526-H544 AromaticContact CD1-CE1 3.38Å; Y526-H544 WeakPolarHBondContact CD1-CE1 3.38Å; Y526-H544 AromaticContact CD1-NE2 3.19Å; Y526-H544 WeakPolarHBondContact CD1-NE2 3.38Å; Y526-H544 AromaticContact CE1-CE1 3.38Å; Y526-H544 WeakPolarHBondContact CE1-CE1 3.26Å; Y526-H544 AromaticContact CE1-NE2 3.6Å
527	I	92.9	Very high	90.5	Very high	23 Å²	23	49.5 Å²	49.5	12%	0.118	23%	0.234	C	C	.	.	H	α-helix	trans	-62.2	-47	175.7	-68.2	163.5	0	0	0	110.4	S523 L524 L530 H531 L536 L541 H544	S523-I527 VanDerWaalsContact O-CG1 3.3Å; S523-I527 WeakPolarHBondContact O-CG1 3.25Å; S523-I527 PolarHBondContact O-N 3.2Å; L524-I527 PolarHBondContact O-N 3.02Å; I527-L530 PolarHBondContact O-N 2.91Å; I527-H531 WeakPolarHBondContact O-CB 3.33Å; I527-H531 PolarHBondContact O-N 3.28Å; I527-L536 HydrophobicContact CG2-CD1 4.34Å; I527-L536 HydrophobicContact CG2-CD2 4.47Å; I527-L541 HydrophobicContact CD1-CD1 4.13Å; I527-L541 HydrophobicContact CG1-CD1 4.37Å; I527-L541 HydrophobicContact CG2-CD1 4.01Å; I527-H544 HydrophobicContact CD1-CB 3.71Å; I527-H544 HydrophobicContact CG1-CB 3.97Å
528	I	90.6	Very high	90.6	Very high	50 Å²	50	59 Å²	59	26%	0.256	27%	0.27	S	S	.	.	H	α-helix	trans	-62.7	-46.8	-179.2	-66.5	165.3	0	0	0	110.4	Y192 F193 L524 L530 H531 Q532	Y192-I528 HydrophobicContact CD1-CB 4.35Å; Y192-I528 HydrophobicContact CD1-CG2 3.84Å; Y192-I528 HydrophobicContact CE1-CG2 4.23Å; F193-I528 HydrophobicContact CD1-CD1 4.39Å; F193-I528 HydrophobicContact CE1-CD1 3.64Å; F193-I528 HydrophobicContact CZ-CD1 4.06Å; L524-I528 WeakPolarHBondContact O-CB 3.09Å; L524-I528 VanDerWaalsContact O-CG1 3.27Å; L524-I528 WeakPolarHBondContact O-CG1 3.37Å; L524-I528 PolarHBondContact O-N 3.05Å; I528-L530 VanDerWaalsContact C-N 3.35Å; I528-L530 PolarHBondContact O-N 3.49Å; I528-H531 WeakPolarHBondContact O-CB 3.37Å; I528-H531 PolarHBondContact O-N 3.43Å; I528-H531 VanDerWaalsContact O-N 3.17Å; I528-Q532 WeakPolarHBondContact O-CG 3.27Å; I528-Q532 PolarHBondContact O-N 2.86Å
529	S	88.6	Confident	90.7	Very high	4 Å²	4	63.8 Å²	63.8	3%	0.028	30%	0.301	C	S	.	.	H	α-helix	trans	-59.8	-42.7	177	170.1	0	0	0	0	112.1	I525 H531 Q532 E533	I525-S529 VanDerWaalsContact O-CB 3.27Å; I525-S529 WeakPolarHBondContact O-CB 3.33Å; I525-S529 PolarHBondContact O-N 3Å; S529-H531 VanDerWaalsContact C-N 3.34Å; S529-H531 PolarHBondContact O-N 3.22Å; S529-Q532 PolarHBondContact O-N 2.66Å; S529-E533 PolarHBondContact O-N 3.39Å; S529-E533 VanDerWaalsContact O-N 3.12Å
530	L	89.3	Confident	90.6	Very high	6 Å²	6	67.1 Å²	67.1	3%	0.031	32%	0.315	C	S	.	.	H	α-helix	trans	-67.3	-33.3	175.7	-80.3	177.4	0	0	0	113.5	Y526 I527 I528 E533 E534 R535 L536 K540	Y526-L530 HydrophobicContact CD1-CD1 3.94Å; Y526-L530 HydrophobicContact CD2-CG 4.39Å; Y526-L530 HydrophobicContact CE1-CD1 3.36Å; Y526-L530 HydrophobicContact CE1-CG 4.21Å; Y526-L530 HydrophobicContact CE2-CD1 3.95Å; Y526-L530 HydrophobicContact CE2-CD2 4.3Å; Y526-L530 HydrophobicContact CE2-CG 3.89Å; Y526-L530 WeakPolarHBondContact O-CB 3.34Å; Y526-L530 WeakPolarHBondContact O-CG 3.36Å; Y526-L530 PolarHBondContact O-N 3.32Å; I527-L530 PolarHBondContact O-N 2.91Å; I528-L530 VanDerWaalsContact C-N 3.35Å; I528-L530 PolarHBondContact O-N 3.49Å; L530-E533 PolarHBondContact O-N 2.83Å; L530-E534 PolarHBondContact O-N 3.49Å; L530-R535 HydrophobicContact CD2-CB 4.16Å; L530-R535 PolarHBondContact O-N 3.46Å; L530-L536 HydrophobicContact CB-CB 4.29Å; L530-L536 HydrophobicContact CB-CD1 4.01Å; L530-L536 HydrophobicContact CD1-CD1 4.12Å; L530-L536 PolarHBondContact O-N 2.9Å; L530-K540 HydrophobicContact CD1-CD 3.96Å
531	H	88.7	Confident	90.6	Very high	130 Å²	130	67.3 Å²	67.3	60%	0.602	32%	0.317	S	S	*	.	H	α-helix	trans	-68.6	-41.8	176.9	-175.5	65.9	0	0	0	110.9	I527 I528 S529 E533 E534 L536	I527-H531 WeakPolarHBondContact O-CB 3.33Å; I527-H531 PolarHBondContact O-N 3.28Å; I528-H531 WeakPolarHBondContact O-CB 3.37Å; I528-H531 PolarHBondContact O-N 3.43Å; I528-H531 VanDerWaalsContact O-N 3.17Å; S529-H531 VanDerWaalsContact C-N 3.34Å; S529-H531 PolarHBondContact O-N 3.22Å; H531-E533 VanDerWaalsContact C-N 3.28Å; H531-E533 PolarHBondContact O-N 2.87Å; H531-E534 PolarHBondContact O-N 2.97Å; H531-L536 HydrophobicContact CB-CD2 4.41Å
532	Q	86.4	Confident	90.7	Very high	136 Å²	136	71.1 Å²	71.1	64%	0.636	34%	0.341	S	S	*	.	H	α-helix	trans	-63	-33.5	174.3	-72.1	174.6	-18.6	0	0	112.8	I528 S529 E534	I528-Q532 WeakPolarHBondContact O-CG 3.27Å; I528-Q532 PolarHBondContact O-N 2.86Å; S529-Q532 PolarHBondContact O-N 2.66Å; Q532-E534 VanDerWaalsContact C-N 3.28Å
533	E	87.4	Confident	90.9	Very high	78 Å²	78	75.8 Å²	75.8	36%	0.364	36%	0.361	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.1	-0.7	173.8	-71.6	-178.7	-158.5	0	0	113.8	S529 L530 H531 R535	S529-E533 PolarHBondContact O-N 3.39Å; S529-E533 VanDerWaalsContact O-N 3.12Å; L530-E533 PolarHBondContact O-N 2.83Å; H531-E533 VanDerWaalsContact C-N 3.28Å; H531-E533 PolarHBondContact O-N 2.87Å; E533-R535 HydrophobicContact CB-CB 4.33Å; E533-R535 HydrophobicContact CB-CG 4.29Å; E533-R535 WeakPolarHBondContact O-CG 3.25Å; E533-R535 PolarHBondContact O-N 3.5Å; E533-R535 VanDerWaalsContact O-N 3.11Å; E533-R535 IonicContact OE2-NH1 2.81Å; E533-R535 PolarHBondContact OE2-NH1 3.31Å; E533-R535 VanDerWaalsContact OE2-NH1 3.14Å
534	E	86	Confident	91	Very high	184 Å²	184	75.8 Å²	75.8	86%	0.86	36%	0.361	S	S	*	.	T	Hydrogen-bonded Turn	trans	54.9	22.5	-171.8	-59.5	-171.4	164.9	0	0	114.6	L530 H531 Q532	L530-E534 PolarHBondContact O-N 3.49Å; H531-E534 PolarHBondContact O-N 2.97Å; Q532-E534 VanDerWaalsContact C-N 3.28Å
535	R	89.1	Confident	91.1	Very high	158 Å²	158	76 Å²	76	60%	0.596	36%	0.364	S	S	*	.			trans	-105.7	14.7	-177	-71	173.2	74.4	-159.6	10.3	113.4	L530 E533 T537	L530-R535 HydrophobicContact CD2-CB 4.16Å; L530-R535 PolarHBondContact O-N 3.46Å; E533-R535 HydrophobicContact CB-CB 4.33Å; E533-R535 HydrophobicContact CB-CG 4.29Å; E533-R535 WeakPolarHBondContact O-CG 3.25Å; E533-R535 PolarHBondContact O-N 3.5Å; E533-R535 VanDerWaalsContact O-N 3.11Å; E533-R535 IonicContact OE2-NH1 2.81Å; E533-R535 PolarHBondContact OE2-NH1 3.31Å; E533-R535 VanDerWaalsContact OE2-NH1 3.14Å; R535-T537 PolarHBondContact O-N 3.26Å
536	L	89.3	Confident	91.3	Very high	57 Å²	57	81.2 Å²	81.2	30%	0.298	39%	0.387	S	S	.	.			trans	-73.8	117.4	-179.4	-173.3	67	0	0	0	110.3	I527 L530 H531 L541	I527-L536 HydrophobicContact CG2-CD1 4.34Å; I527-L536 HydrophobicContact CG2-CD2 4.47Å; L530-L536 HydrophobicContact CB-CB 4.29Å; L530-L536 HydrophobicContact CB-CD1 4.01Å; L530-L536 HydrophobicContact CD1-CD1 4.12Å; L530-L536 PolarHBondContact O-N 2.9Å; H531-L536 HydrophobicContact CB-CD2 4.41Å; L536-L541 HydrophobicContact CD1-CB 4.47Å
537	T	91.9	Very high	91.5	Very high	63 Å²	63	79.8 Å²	79.8	39%	0.387	38%	0.381	S	S	.	.			trans	-106.4	147.3	174.3	61.6	0	0	0	0	110.8	R535 K540 L541	R535-T537 PolarHBondContact O-N 3.26Å; T537-K540 PolarHBondContact O-N 3.14Å; T537-K540 VanDerWaalsContact O-N 3.11Å; T537-K540 WeakPolarHBondContact OG1-CD 3.46Å; T537-K540 WeakPolarHBondContact OG1-CG 3.49Å; T537-L541 PolarHBondContact O-N 3.15Å; T537-L541 VanDerWaalsContact O-N 3.08Å
538	W	91	Very high	91.6	Very high	201 Å²	201	80.2 Å²	80.2	76%	0.761	38%	0.383	S	S	*	.	H	α-helix	trans	-51.4	-46	178.6	-84.7	105.1	0	0	0	114.5	K540 L541 V542	W538-K540 VanDerWaalsContact C-N 3.29Å; W538-K540 PolarHBondContact O-N 3.27Å; W538-L541 HydrophobicContact CE3-CD2 4.17Å; W538-L541 HydrophobicContact CZ3-CD2 4.08Å; W538-L541 WeakPolarHBondContact O-CB 3.5Å; W538-L541 PolarHBondContact O-N 3.42Å; W538-L541 VanDerWaalsContact O-N 3.16Å; W538-V542 WeakPolarHBondContact O-CG2 3.48Å; W538-V542 PolarHBondContact O-N 2.88Å
539	P	92.9	Very high	91.9	Very high	99 Å²	99	82.6 Å²	82.6	64%	0.643	40%	0.395	S	S	*	.	H	α-helix	trans	-61.2	-37.2	179	-24.6	34.8	0	0	0	113.1	F543	P539-F543 WeakPolarHBondContact O-CB 3.08Å; P539-F543 PolarHBondContact O-N 2.93Å; P539-F543 VanDerWaalsContact O-N 3.1Å
540	K	91.4	Very high	92.2	Very high	73 Å²	73	85.5 Å²	85.5	32%	0.317	41%	0.411	S	S	.	.	H	α-helix	trans	-68.3	-41.1	177.1	-68	176.2	-170.9	167.7	0	110.8	L530 T537 W538 F543 H544	L530-K540 HydrophobicContact CD1-CD 3.96Å; T537-K540 PolarHBondContact O-N 3.14Å; T537-K540 VanDerWaalsContact O-N 3.11Å; T537-K540 WeakPolarHBondContact OG1-CD 3.46Å; T537-K540 WeakPolarHBondContact OG1-CG 3.49Å; W538-K540 VanDerWaalsContact C-N 3.29Å; W538-K540 PolarHBondContact O-N 3.27Å; K540-F543 PolarHBondContact O-N 3.42Å; K540-H544 PolarHBondContact O-N 2.86Å; K540-H544 VanDerWaalsContact O-N 3.16Å; K540-H544 PolarHBondContact O-ND1 2.69Å
541	L	93.4	Very high	92.4	Very high	45 Å²	45	85.2 Å²	85.2	24%	0.236	41%	0.409	C	S	.	.	H	α-helix	trans	-60.6	-51.9	177.2	-178.7	65.2	0	0	0	110.8	I527 L536 T537 W538 F543 H544 V545	I527-L541 HydrophobicContact CD1-CD1 4.13Å; I527-L541 HydrophobicContact CG1-CD1 4.37Å; I527-L541 HydrophobicContact CG2-CD1 4.01Å; L536-L541 HydrophobicContact CD1-CB 4.47Å; T537-L541 PolarHBondContact O-N 3.15Å; T537-L541 VanDerWaalsContact O-N 3.08Å; W538-L541 HydrophobicContact CE3-CD2 4.17Å; W538-L541 HydrophobicContact CZ3-CD2 4.08Å; W538-L541 WeakPolarHBondContact O-CB 3.5Å; W538-L541 PolarHBondContact O-N 3.42Å; W538-L541 VanDerWaalsContact O-N 3.16Å; L541-F543 VanDerWaalsContact C-N 3.31Å; L541-F543 PolarHBondContact O-N 3.26Å; L541-H544 PolarHBondContact O-N 2.93Å; L541-V545 HydrophobicContact CD1-CG2 4.12Å; L541-V545 HydrophobicContact CG-CG2 4.34Å; L541-V545 WeakPolarHBondContact O-CB 3.29Å; L541-V545 VanDerWaalsContact O-CG2 3.29Å; L541-V545 WeakPolarHBondContact O-CG2 3.36Å; L541-V545 PolarHBondContact O-N 3.14Å
542	V	95.4	Very high	92.7	Very high	91 Å²	91	81.8 Å²	81.8	55%	0.552	40%	0.397	S	S	*	.	H	α-helix	trans	-57.5	-44.7	-179.8	173.6	0	0	0	0	111.3	W538 H544 V545 F546	W538-V542 WeakPolarHBondContact O-CG2 3.48Å; W538-V542 PolarHBondContact O-N 2.88Å; V542-H544 PolarHBondContact O-N 3.43Å; V542-V545 PolarHBondContact O-N 3.43Å; V542-F546 WeakPolarHBondContact O-CB 3.39Å; V542-F546 PolarHBondContact O-N 3.47Å
543	F	95.1	Very high	93.1	Very high	101 Å²	101	77.2 Å²	77.2	44%	0.443	38%	0.383	S	S	.	.	H	α-helix	trans	-61.3	-43.6	179	-179.6	-103.8	0	0	0	113	Y163 P539 K540 L541 F546 I547	Y163-F543 HydrophobicContact CD1-CE1 4.48Å; Y163-F543 AromaticContact CE1-CE1 3.76Å; Y163-F543 HydrophobicContact CE1-CE1 3.76Å; Y163-F543 HydrophobicContact CE2-CE1 4.47Å; Y163-F543 AromaticContact CZ-CE1 3.73Å; P539-F543 WeakPolarHBondContact O-CB 3.08Å; P539-F543 PolarHBondContact O-N 2.93Å; P539-F543 VanDerWaalsContact O-N 3.1Å; K540-F543 PolarHBondContact O-N 3.42Å; L541-F543 VanDerWaalsContact C-N 3.31Å; L541-F543 PolarHBondContact O-N 3.26Å; F543-F546 WeakPolarHBondContact O-CB 3.34Å; F543-F546 PolarHBondContact O-N 3.36Å; F543-I547 HydrophobicContact CD1-CD1 4.11Å; F543-I547 HydrophobicContact CE1-CD1 3.59Å; F543-I547 HydrophobicContact CZ-CD1 3.94Å; F543-I547 WeakPolarHBondContact O-CG1 3.34Å; F543-I547 PolarHBondContact O-N 3.05Å
544	H	94.8	Very high	93.4	Very high	3 Å²	3	74.1 Å²	74.1	1%	0.014	37%	0.369	C	S	.	.	H	α-helix	trans	-75.6	-34	-179.4	-70.3	82.2	0	0	0	112.5	Y163 Y526 I527 K540 L541 V542 F546 I547 I548	Y163-H544 AromaticContact CE1-NE2 3.96Å; Y163-H544 AromaticContact CZ-NE2 3.75Å; Y163-H544 PolarHBondContact OH-CE1 3.32Å; Y163-H544 PolarHBondContact OH-NE2 2.8Å; Y526-H544 AromaticContact CD1-CD2 3.79Å; Y526-H544 AromaticContact CD1-CE1 3.38Å; Y526-H544 WeakPolarHBondContact CD1-CE1 3.38Å; Y526-H544 AromaticContact CD1-NE2 3.19Å; Y526-H544 WeakPolarHBondContact CD1-NE2 3.38Å; Y526-H544 AromaticContact CE1-CE1 3.38Å; Y526-H544 WeakPolarHBondContact CE1-CE1 3.26Å; Y526-H544 AromaticContact CE1-NE2 3.6Å; I527-H544 HydrophobicContact CD1-CB 3.71Å; I527-H544 HydrophobicContact CG1-CB 3.97Å; K540-H544 PolarHBondContact O-N 2.86Å; K540-H544 VanDerWaalsContact O-N 3.16Å; K540-H544 PolarHBondContact O-ND1 2.69Å; L541-H544 PolarHBondContact O-N 2.93Å; V542-H544 PolarHBondContact O-N 3.43Å; H544-F546 VanDerWaalsContact C-N 3.29Å; H544-I547 PolarHBondContact O-N 2.92Å; H544-I548 WeakPolarHBondContact O-CG1 3.33Å; H544-I548 PolarHBondContact O-N 2.9Å; H544-I548 VanDerWaalsContact O-N 3.12Å
545	V	95.3	Very high	93.8	Very high	60 Å²	60	67.1 Å²	67.1	36%	0.364	34%	0.337	S	S	.	.	H	α-helix	trans	-63.1	-39.5	171.4	171.9	0	0	0	0	110.5	L541 V542 I547 I548 I549	L541-V545 HydrophobicContact CD1-CG2 4.12Å; L541-V545 HydrophobicContact CG-CG2 4.34Å; L541-V545 WeakPolarHBondContact O-CB 3.29Å; L541-V545 VanDerWaalsContact O-CG2 3.29Å; L541-V545 WeakPolarHBondContact O-CG2 3.36Å; L541-V545 PolarHBondContact O-N 3.14Å; V542-V545 PolarHBondContact O-N 3.43Å; V545-I547 PolarHBondContact O-N 3.18Å; V545-I548 WeakPolarHBondContact O-CB 2.79Å; V545-I548 PolarHBondContact O-N 2.86Å; V545-I549 HydrophobicContact CG1-CD1 3.94Å; V545-I549 HydrophobicContact CG1-CG1 4.45Å; V545-I549 WeakPolarHBondContact O-CG1 3.48Å; V545-I549 PolarHBondContact O-N 2.86Å
546	F	95.9	Very high	94	Very high	113 Å²	113	63.7 Å²	63.7	50%	0.496	33%	0.329	S	S	.	.	H	α-helix	trans	-59.8	-43.1	174.1	177.2	-107.3	0	0	0	112.4	V542 F543 H544 I548 I549 L550	V542-F546 WeakPolarHBondContact O-CB 3.39Å; V542-F546 PolarHBondContact O-N 3.47Å; F543-F546 WeakPolarHBondContact O-CB 3.34Å; F543-F546 PolarHBondContact O-N 3.36Å; H544-F546 VanDerWaalsContact C-N 3.29Å; F546-I548 VanDerWaalsContact C-N 3.31Å; F546-I548 PolarHBondContact O-N 3.32Å; F546-I549 PolarHBondContact O-N 2.94Å; F546-L550 HydrophobicContact CD1-CD1 3.97Å; F546-L550 HydrophobicContact CD1-CG 4.38Å; F546-L550 HydrophobicContact CE1-CD1 3.44Å; F546-L550 VanDerWaalsContact CE1-CD1 3.44Å; F546-L550 HydrophobicContact CE1-CD2 4.47Å; F546-L550 HydrophobicContact CE1-CG 4Å; F546-L550 HydrophobicContact CE2-CD2 4.27Å; F546-L550 HydrophobicContact CE2-CG 4.26Å; F546-L550 HydrophobicContact CZ-CD1 3.78Å; F546-L550 HydrophobicContact CZ-CD2 3.96Å; F546-L550 HydrophobicContact CZ-CG 3.93Å; F546-L550 WeakPolarHBondContact O-CG 3.25Å; F546-L550 PolarHBondContact O-N 3.38Å
547	I	95.5	Very high	94.2	Very high	1 Å²	1	63 Å²	63	1%	0.005	33%	0.327	C	S	.	.	H	α-helix	trans	-60	-41.2	174.9	-66	174.1	0	0	0	111.5	L160 Y163 F519 F543 H544 V545 L550 G551	L160-I547 HydrophobicContact CD1-CD1 4.17Å; L160-I547 HydrophobicContact CD1-CG1 4.03Å; L160-I547 HydrophobicContact CD1-CG2 4.31Å; Y163-I547 HydrophobicContact CD1-CD1 3.93Å; Y163-I547 HydrophobicContact CE1-CD1 3.65Å; F519-I547 HydrophobicContact CB-CG2 4.32Å; F519-I547 HydrophobicContact CD1-CG2 3.85Å; F543-I547 HydrophobicContact CD1-CD1 4.11Å; F543-I547 HydrophobicContact CE1-CD1 3.59Å; F543-I547 HydrophobicContact CZ-CD1 3.94Å; F543-I547 WeakPolarHBondContact O-CG1 3.34Å; F543-I547 PolarHBondContact O-N 3.05Å; H544-I547 PolarHBondContact O-N 2.92Å; V545-I547 PolarHBondContact O-N 3.18Å; I547-L550 PolarHBondContact O-N 3.15Å; I547-G551 PolarHBondContact O-N 3.45Å
548	I	95.9	Very high	94.2	Very high	32 Å²	32	60 Å²	60	16%	0.164	31%	0.309	C	S	.	.	H	α-helix	trans	-62.7	-46.2	176.7	-67.9	168.3	0	0	0	110.6	I520 L524 H544 V545 F546 L550 G551 V552	I520-I548 HydrophobicContact CG1-CG2 4.12Å; L524-I548 HydrophobicContact CD2-CD1 3.89Å; L524-I548 HydrophobicContact CG-CD1 4.11Å; H544-I548 WeakPolarHBondContact O-CG1 3.33Å; H544-I548 PolarHBondContact O-N 2.9Å; H544-I548 VanDerWaalsContact O-N 3.12Å; V545-I548 WeakPolarHBondContact O-CB 2.79Å; V545-I548 PolarHBondContact O-N 2.86Å; F546-I548 VanDerWaalsContact C-N 3.31Å; F546-I548 PolarHBondContact O-N 3.32Å; I548-L550 VanDerWaalsContact C-N 3.32Å; I548-L550 PolarHBondContact O-N 2.73Å; I548-G551 PolarHBondContact O-N 3.29Å; I548-G551 VanDerWaalsContact O-N 3.16Å; I548-V552 WeakPolarHBondContact O-CG2 3.43Å; I548-V552 PolarHBondContact O-N 3.07Å
549	I	96.3	Very high	94.2	Very high	99 Å²	99	57.2 Å²	57.2	51%	0.508	30%	0.302	S	S	.	.	H	α-helix	trans	-60.8	-42.4	177.8	-67.5	167.4	0	0	0	110.8	V545 F546 G551 V552 A553	V545-I549 HydrophobicContact CG1-CD1 3.94Å; V545-I549 HydrophobicContact CG1-CG1 4.45Å; V545-I549 WeakPolarHBondContact O-CG1 3.48Å; V545-I549 PolarHBondContact O-N 2.86Å; F546-I549 PolarHBondContact O-N 2.94Å; I549-G551 VanDerWaalsContact C-N 3.33Å; I549-G551 PolarHBondContact O-N 2.86Å; I549-V552 PolarHBondContact O-N 3.02Å; I549-A553 VanDerWaalsContact O-CB 3.31Å; I549-A553 WeakPolarHBondContact O-CB 3.47Å; I549-A553 PolarHBondContact O-N 3.28Å
550	L	94.4	Very high	93.8	Very high	66 Å²	66	60.5 Å²	60.5	35%	0.346	31%	0.307	S	S	.	.	H	α-helix	trans	-59.5	-42.2	175	-73.6	179.6	0	0	0	112.2	L160 F546 I547 I548 A553 N554	L160-L550 HydrophobicContact CD2-CD1 4.37Å; F546-L550 HydrophobicContact CD1-CD1 3.97Å; F546-L550 HydrophobicContact CD1-CG 4.38Å; F546-L550 HydrophobicContact CE1-CD1 3.44Å; F546-L550 VanDerWaalsContact CE1-CD1 3.44Å; F546-L550 HydrophobicContact CE1-CD2 4.47Å; F546-L550 HydrophobicContact CE1-CG 4Å; F546-L550 HydrophobicContact CE2-CD2 4.27Å; F546-L550 HydrophobicContact CE2-CG 4.26Å; F546-L550 HydrophobicContact CZ-CD1 3.78Å; F546-L550 HydrophobicContact CZ-CD2 3.96Å; F546-L550 HydrophobicContact CZ-CG 3.93Å; F546-L550 WeakPolarHBondContact O-CG 3.25Å; F546-L550 PolarHBondContact O-N 3.38Å; I547-L550 PolarHBondContact O-N 3.15Å; I548-L550 VanDerWaalsContact C-N 3.32Å; I548-L550 PolarHBondContact O-N 2.73Å; L550-A553 PolarHBondContact O-N 2.87Å; L550-N554 WeakPolarHBondContact O-CB 3.15Å; L550-N554 PolarHBondContact O-N 2.93Å
551	G	93.9	Very high	93	Very high	0 Å²	0	60.9 Å²	60.9	0%	0	31%	0.311	C	S	.	.	H	α-helix	trans	-62.6	-44.6	176.3	0	0	0	0	0	112.7	L515 I547 I548 I549 N554 L555	L515-G551 VanDerWaalsContact CD1-C 3.48Å; I547-G551 PolarHBondContact O-N 3.45Å; I548-G551 PolarHBondContact O-N 3.29Å; I548-G551 VanDerWaalsContact O-N 3.16Å; I549-G551 VanDerWaalsContact C-N 3.33Å; I549-G551 PolarHBondContact O-N 2.86Å; G551-N554 WeakPolarHBondContact O-CB 3.36Å; G551-N554 PolarHBondContact O-N 3.18Å; G551-L555 PolarHBondContact O-N 3.39Å
552	V	95.2	Very high	92.9	Very high	58 Å²	58	61.7 Å²	61.7	35%	0.352	32%	0.315	S	S	.	.	H	α-helix	trans	-63.7	-46	176.5	173.7	0	0	0	0	110.7	L515 I548 I549 N554 L555 I556	L515-V552 HydrophobicContact CD1-CB 4.37Å; L515-V552 HydrophobicContact CD1-CG2 3.74Å; I548-V552 WeakPolarHBondContact O-CG2 3.43Å; I548-V552 PolarHBondContact O-N 3.07Å; I549-V552 PolarHBondContact O-N 3.02Å; V552-N554 VanDerWaalsContact C-N 3.32Å; V552-N554 PolarHBondContact O-N 3.19Å; V552-L555 PolarHBondContact O-N 3Å; V552-I556 HydrophobicContact CG1-CD1 3.59Å; V552-I556 HydrophobicContact CG1-CG1 4.3Å; V552-I556 WeakPolarHBondContact O-CG1 3.07Å; V552-I556 PolarHBondContact O-N 3.33Å
553	A	94.3	Very high	92.8	Very high	40 Å²	40	60.2 Å²	60.2	33%	0.331	30%	0.302	S	S	.	.	H	α-helix	trans	-60	-42.5	176.4	0	0	0	0	0	111.6	I549 L550 L555 I556 V557	I549-A553 VanDerWaalsContact O-CB 3.31Å; I549-A553 WeakPolarHBondContact O-CB 3.47Å; I549-A553 PolarHBondContact O-N 3.28Å; L550-A553 PolarHBondContact O-N 2.87Å; A553-L555 VanDerWaalsContact C-N 3.29Å; A553-L555 PolarHBondContact O-N 3.24Å; A553-I556 PolarHBondContact O-N 3.37Å; A553-V557 WeakPolarHBondContact O-CB 3.38Å; A553-V557 WeakPolarHBondContact O-CG2 3.16Å; A553-V557 PolarHBondContact O-N 3.33Å
554	N	93.9	Very high	92.7	Very high	13 Å²	13	57.9 Å²	57.9	7%	0.07	29%	0.294	C	S	.	.	H	α-helix	trans	-56.9	-41.8	178.2	-175	35.4	0	0	0	111.9	T363 T367 L550 G551 V552 Q558	T363-N554 WeakPolarHBondContact CB-OD1 3.38Å; T363-N554 PolarHBondContact OG1-OD1 3.09Å; T367-N554 PolarHBondContact OG1-ND2 3.45Å; L550-N554 WeakPolarHBondContact O-CB 3.15Å; L550-N554 PolarHBondContact O-N 2.93Å; G551-N554 WeakPolarHBondContact O-CB 3.36Å; G551-N554 PolarHBondContact O-N 3.18Å; V552-N554 VanDerWaalsContact C-N 3.32Å; V552-N554 PolarHBondContact O-N 3.19Å; N554-Q558 VanDerWaalsContact O-CG 3.28Å; N554-Q558 WeakPolarHBondContact O-CG 3.24Å; N554-Q558 PolarHBondContact O-NE2 3.32Å; N554-Q558 VanDerWaalsContact O-NE2 3.1Å; N554-Q558 PolarHBondContact OD1-NE2 3Å
555	L	94.1	Very high	92.5	Very high	37 Å²	37	61.1 Å²	61.1	19%	0.194	31%	0.311	C	S	.	.	H	α-helix	trans	-71.7	-48.4	177.2	-179.6	63.5	0	0	0	112.3	A511 A512 L515 G551 V552 A553 V557 Q558 F559	A511-L555 HydrophobicContact CB-CB 4.48Å; A511-L555 HydrophobicContact CB-CD1 3.94Å; A512-L555 HydrophobicContact CB-CD1 4.34Å; L515-L555 HydrophobicContact CD2-CD2 3.64Å; G551-L555 PolarHBondContact O-N 3.39Å; V552-L555 PolarHBondContact O-N 3Å; A553-L555 VanDerWaalsContact C-N 3.29Å; A553-L555 PolarHBondContact O-N 3.24Å; L555-V557 VanDerWaalsContact C-N 3.31Å; L555-V557 PolarHBondContact O-N 2.86Å; L555-Q558 PolarHBondContact O-N 3.03Å; L555-F559 HydrophobicContact CD1-CE2 3.95Å; L555-F559 HydrophobicContact CG-CE2 4.08Å; L555-F559 VanDerWaalsContact O-CD2 3.28Å; L555-F559 WeakPolarHBondContact O-CD2 3.04Å
556	I	94.3	Very high	92.4	Very high	85 Å²	85	61.2 Å²	61.2	44%	0.436	31%	0.308	S	S	.	.	H	α-helix	trans	-59.1	-45.3	-177.2	-70.4	175.5	0	0	0	110.5	V552 A553 Q558 F559 F560	V552-I556 HydrophobicContact CG1-CD1 3.59Å; V552-I556 HydrophobicContact CG1-CG1 4.3Å; V552-I556 WeakPolarHBondContact O-CG1 3.07Å; V552-I556 PolarHBondContact O-N 3.33Å; A553-I556 PolarHBondContact O-N 3.37Å; I556-Q558 VanDerWaalsContact C-N 3.26Å; I556-Q558 PolarHBondContact O-N 3.02Å; I556-F559 PolarHBondContact O-N 2.94Å; I556-F559 VanDerWaalsContact O-N 3.11Å; I556-F560 HydrophobicContact CG2-CD2 3.98Å; I556-F560 HydrophobicContact CG2-CE2 3.54Å; I556-F560 VanDerWaalsContact O-CD2 3.3Å; I556-F560 WeakPolarHBondContact O-CD2 3.3Å
557	V	92.2	Very high	92.1	Very high	43 Å²	43	57.7 Å²	57.7	26%	0.261	30%	0.295	S	S	.	.	H	α-helix	trans	-68.4	-23.8	-175.7	-178.8	0	0	0	0	112.4	P360 A553 L555 F559 F560 M561	P360-V557 HydrophobicContact CB-CB 4.18Å; P360-V557 HydrophobicContact CB-CG1 3.49Å; P360-V557 VanDerWaalsContact CB-CG1 3.49Å; P360-V557 HydrophobicContact CG-CB 4.44Å; P360-V557 HydrophobicContact CG-CG1 3.41Å; P360-V557 VanDerWaalsContact CG-CG1 3.41Å; A553-V557 WeakPolarHBondContact O-CB 3.38Å; A553-V557 WeakPolarHBondContact O-CG2 3.16Å; A553-V557 PolarHBondContact O-N 3.33Å; L555-V557 VanDerWaalsContact C-N 3.31Å; L555-V557 PolarHBondContact O-N 2.86Å; V557-F559 PolarHBondContact O-N 3.24Å; V557-F560 PolarHBondContact O-N 3.29Å; V557-F560 VanDerWaalsContact O-N 3.16Å; V557-M561 HydrophobicContact CG1-CE 3.79Å; V557-M561 HydrophobicContact CG1-CG 4.48Å; V557-M561 HydrophobicContact CG1-SD 4.33Å
558	Q	92.4	Very high	91.9	Very high	0 Å²	0	61.8 Å²	61.8	0%	0	32%	0.316	C	S	.	.	H	α-helix	trans	-62	-26.1	173	-59.1	-47	-46.5	0	0	113.2	P360 Y508 A511 N554 L555 I556	P360-Q558 PolarHBondContact O-NE2 3.42Å; Y508-Q558 HydrophobicContact CD1-CB 3.91Å; Y508-Q558 HydrophobicContact CE1-CB 3.72Å; Y508-Q558 PolarHBondContact OH-O 3.13Å; A511-Q558 HydrophobicContact CB-CG 3.76Å; N554-Q558 VanDerWaalsContact O-CG 3.28Å; N554-Q558 WeakPolarHBondContact O-CG 3.24Å; N554-Q558 PolarHBondContact O-NE2 3.32Å; N554-Q558 VanDerWaalsContact O-NE2 3.1Å; N554-Q558 PolarHBondContact OD1-NE2 3Å; L555-Q558 PolarHBondContact O-N 3.03Å; I556-Q558 VanDerWaalsContact C-N 3.26Å; I556-Q558 PolarHBondContact O-N 3.02Å
559	F	91.1	Very high	91.6	Very high	142 Å²	142	64.1 Å²	64.1	62%	0.623	33%	0.328	S	S	*	.	H	α-helix	trans	-83.4	-19.1	179.4	-66.3	-77.4	0	0	0	112.9	Y508 L555 I556 V557	Y508-F559 HydrophobicContact CE1-CD1 4.23Å; Y508-F559 HydrophobicContact CE1-CE1 4.19Å; L555-F559 HydrophobicContact CD1-CE2 3.95Å; L555-F559 HydrophobicContact CG-CE2 4.08Å; L555-F559 VanDerWaalsContact O-CD2 3.28Å; L555-F559 WeakPolarHBondContact O-CD2 3.04Å; I556-F559 PolarHBondContact O-N 2.94Å; I556-F559 VanDerWaalsContact O-N 3.11Å; V557-F559 PolarHBondContact O-N 3.24Å
560	F	85.5	Confident	91.2	Very high	169 Å²	169	61.2 Å²	61.2	74%	0.741	31%	0.313	S	S	*	.			trans	-90.6	-1.3	179	-71.2	-73.1	0	0	0	113.2	I556 V557	I556-F560 HydrophobicContact CG2-CD2 3.98Å; I556-F560 HydrophobicContact CG2-CE2 3.54Å; I556-F560 VanDerWaalsContact O-CD2 3.3Å; I556-F560 WeakPolarHBondContact O-CD2 3.3Å; V557-F560 PolarHBondContact O-N 3.29Å; V557-F560 VanDerWaalsContact O-N 3.16Å
561	M	73	Confident	90.9	Very high	81 Å²	81	60.7 Å²	60.7	40%	0.399	31%	0.31	S	S	.	.			trans	-135.4	0	-175.9	-60.1	-164.1	-177.5	0	0	113.8	F357 Q358 P360 R507 V557	F357-M561 WeakPolarHBondContact O-CE 3.2Å; F357-M561 VanDerWaalsContact O-SD 3.41Å; Q358-M561 HydrophobicContact CB-SD 4.44Å; P360-M561 HydrophobicContact CB-SD 4.33Å; P360-M561 HydrophobicContact CG-CE 3.77Å; P360-M561 HydrophobicContact CG-SD 3.94Å; R507-M561 PolarHBondContact NH1-OXT 3.34Å; R507-M561 PolarHBondContact NH2-OXT 3.12Å; V557-M561 HydrophobicContact CG1-CE 3.79Å; V557-M561 HydrophobicContact CG1-CG 4.48Å; V557-M561 HydrophobicContact CG1-SD 4.33Å

Retrieved 561 of 561 residues in 420.7 ms (Link to these results)

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