A0A096MW88_PAPAN Loading...

TIR domain-containing adapter molecule 2

Functions as a sorting adapter in different signaling pathways to facilitate downstream signaling leading to type I interferon induction. In TLR4 signaling, physically bridges TLR4 and TICAM1 and functionally transmits signal to TICAM1 in early endosomes after endocytosis of TLR4. In TLR2 signaling, physically bridges TLR2 and MYD88 and is required for the TLR2-dependent movement of MYD88 to endosomes following ligand engagement. Involved in IL-18 signaling and is proposed to function as a sorting adapter for MYD88 in IL-18 signaling during adaptive immune response. Forms a complex with RAB11FIP2 that is recruited to the phagosomes to promote the activation of the actin-regulatory GTPases RAC1 and CDC42 and subsequent phagocytosis of Gram-negative bacteria.

AlphaFold DB , UniProt , Accession A0A096MW88, Species PAPAN (Papio anubis, Olive baboon), Gene TICAM2, Length 235 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.3	Very low	44.2	Very low	252 Å²	252	147.7 Å²	147.7	100%	1.241	86%	0.862	S	S	*	*				0	119.6	0	-69.3	-176.7	-74.3	0	0	107
2	G	43.9	Very low	44.2	Very low	78 Å²	78	145.3 Å²	145.3	80%	0.804	85%	0.854	S	S	*	*			cis	-155.3	148.7	-0.6	0	0	0	0	0	108.8
3	I	43.5	Very low	44	Very low	159 Å²	159	147.3 Å²	147.3	82%	0.815	86%	0.858	S	S	*	*			trans	-90.1	113.7	173.5	29.4	168	0	0	0	107.9	K5	I3-K5 PolarHBondContact O-N 3.41Å
4	G	45	Very low	43.9	Very low	82 Å²	82	144.9 Å²	144.9	85%	0.845	85%	0.853	S	S	*	*			trans	-80.1	112.3	173.7	0	0	0	0	0	110.6
5	K	45.7	Very low	43.3	Very low	190 Å²	190	147.1 Å²	147.1	83%	0.826	86%	0.858	S	S	*	*	P	Polyproline II helix	trans	-94.9	118.1	170.1	-71.2	-169.7	172.9	-177.9	0	109	I3	I3-K5 PolarHBondContact O-N 3.41Å
6	S	57.9	Low	42.9	Very low	120 Å²	120	145.3 Å²	145.3	84%	0.839	86%	0.856	S	S	*	*	P	Polyproline II helix	trans	-88.8	116.8	167.3	-43.2	0	0	0	0	108.7
7	K	45.9	Very low	42.4	Very low	194 Å²	194	152.1 Å²	152.1	84%	0.843	86%	0.864	S	S	*	*	P	Polyproline II helix	trans	-74.6	134.2	169.9	-81	175.1	174.5	177.3	0	109.1
8	I	51.7	Low	41.9	Very low	164 Å²	164	147.6 Å²	147.6	84%	0.841	86%	0.856	S	S	*	*			trans	-101.8	115.1	166.9	5.7	169.3	0	0	0	105.6
9	D	38.6	Very low	41.5	Very low	149 Å²	149	149.7 Å²	149.7	80%	0.797	85%	0.854	S	S	*	*			trans	-80.2	119.2	173.8	-76.4	-40.9	0	0	0	109.3
10	S	37.6	Very low	41.2	Very low	118 Å²	118	154.6 Å²	154.6	83%	0.825	86%	0.858	S	S	*	*			trans	-82.9	111.2	171	-65.7	0	0	0	0	109.4
11	C	37.6	Very low	40.8	Very low	119 Å²	119	155.1 Å²	155.1	80%	0.804	85%	0.854	S	S	*	*			trans	-83.4	124.7	167	-64.6	0	0	0	0	110.2
12	P	44.4	Very low	40.5	Very low	118 Å²	118	147.9 Å²	147.9	77%	0.766	83%	0.828	S	S	*	*			trans	-97.7	112	167.5	32.7	-21.8	0	0	0	109.2
13	L	42.2	Very low	40	Very low	172 Å²	172	150.5 Å²	150.5	90%	0.901	83%	0.828	S	S	*	*			trans	-91.1	108.5	164	-71.2	177.2	0	0	0	108.6
14	S	41.9	Very low	39.5	Very low	113 Å²	113	149.8 Å²	149.8	79%	0.79	83%	0.826	S	S	*	*			trans	-68.7	119.7	175	37.2	0	0	0	0	111.1	S16	S14-S16 PolarHBondContact O-N 3.02Å
15	L	36	Very low	39	Very low	178 Å²	178	152 Å²	152	93%	0.932	82%	0.823	S	S	*	*			trans	-81.5	106.5	164.8	-79.9	158.5	0	0	0	108.7	W17	L15-W17 PolarHBondContact O-N 3.13Å
16	S	36.3	Very low	38.5	Very low	119 Å²	119	147.6 Å²	147.6	83%	0.832	82%	0.817	S	S	*	*			trans	-82.6	109.9	168.8	49.7	0	0	0	0	109.9	S14 G18	S14-S16 PolarHBondContact O-N 3.02Å; S16-G18 PolarHBondContact O-N 2.73Å
17	W	34.1	Very low	37.8	Very low	261 Å²	261	147.6 Å²	147.6	99%	0.989	81%	0.813	S	S	*	*			trans	-72	104.7	174	-131.3	-31.3	0	0	0	109.5	L15 K19	L15-W17 PolarHBondContact O-N 3.13Å; W17-K19 PolarHBondContact O-N 2.83Å
18	G	33.3	Very low	36.8	Very low	70 Å²	70	141.7 Å²	141.7	72%	0.722	81%	0.808	S	S	*	*			trans	-80.7	104.1	174.5	0	0	0	0	0	111.8	S16	S16-G18 PolarHBondContact O-N 2.73Å
19	K	33.7	Very low	35.7	Very low	189 Å²	189	144.3 Å²	144.3	82%	0.822	81%	0.809	S	S	*	*			trans	-72.8	127.6	172.2	-158.2	170.1	-173.5	176.3	0	109.7	W17	W17-K19 PolarHBondContact O-N 2.83Å
20	R	36	Very low	35.5	Very low	247 Å²	247	145.9 Å²	145.9	93%	0.932	81%	0.811	S	S	*	*			trans	-121	123.8	164.6	-71.4	-168.9	-173.3	-175.3	3.5	110.1
21	H	33.2	Very low	35.1	Very low	166 Å²	166	147.6 Å²	147.6	77%	0.769	81%	0.806	S	S	*	*			trans	-68.8	130.7	166.8	-89.8	-91.3	0	0	0	109.5
22	S	32.1	Very low	35	Very low	99 Å²	99	147 Å²	147	69%	0.692	80%	0.803	S	S	*	*				61	112.9	92	-171	0	0	0	0	115.2
23	V	32.7	Very low	34.2	Very low	134 Å²	134	148.7 Å²	148.7	81%	0.812	81%	0.806	S	S	*	*				171.5	136.9	115.1	157.3	0	0	0	0	110
24	D	33.4	Very low	33.8	Very low	143 Å²	143	145.2 Å²	145.2	77%	0.765	80%	0.796	S	S	*	*			trans	-75.7	142.5	178.5	-173.6	14.4	0	0	0	112.6
25	T	34.5	Very low	33.3	Very low	129 Å²	129	149.1 Å²	149.1	79%	0.791	80%	0.798	S	S	*	*			trans	-168.5	110.3	148.5	-41.8	0	0	0	0	110.3
26	S	36.2	Very low	33.1	Very low	98 Å²	98	148.7 Å²	148.7	69%	0.685	79%	0.789	S	S	*	*			trans	-88.9	157.9	146.3	91.6	0	0	0	0	108.6
27	P	41.5	Very low	33	Very low	119 Å²	119	149 Å²	149	77%	0.773	79%	0.791	S	S	*	*				-154.7	168.9	83.3	37.7	-17.6	0	0	0	116.5
28	G	26.9	Very low	32.9	Very low	70 Å²	70	143 Å²	143	72%	0.722	77%	0.774	S	S	*	*			trans	120.8	98.1	134.3	0	0	0	0	0	118.7
29	Y	28.3	Very low	32.7	Very low	219 Å²	219	146.1 Å²	146.1	86%	0.859	77%	0.774	S	S	*	*			trans	-1.8	133.9	139.8	-74.1	-98.2	0	0	0	119.2
30	H	33.3	Very low	32.5	Very low	182 Å²	182	144.1 Å²	144.1	84%	0.843	77%	0.772	S	S	*	*				-167.6	142.9	105.9	-114.7	-80.9	0	0	0	113.8
31	E	29.2	Very low	32.3	Very low	154 Å²	154	136.3 Å²	136.3	72%	0.72	76%	0.755	S	S	*	*			trans	-78.1	155.4	179.6	-175.9	176	-152.5	0	0	112.7
32	S	35.6	Very low	32.2	Very low	107 Å²	107	135.4 Å²	135.4	75%	0.748	76%	0.755	S	S	*	*			trans	154.4	105.6	131.4	-64.8	0	0	0	0	114.5
33	D	28.2	Very low	32.1	Very low	154 Å²	154	140.5 Å²	140.5	82%	0.824	76%	0.759	S	S	*	*			trans	23.1	154.3	130.2	-73.5	-30.9	0	0	0	125.9
34	S	32.7	Very low	32	Very low	99 Å²	99	141 Å²	141	69%	0.692	76%	0.757	S	S	*	*			trans	89.3	131.2	148.4	-132.8	0	0	0	0	115.7
35	K	33.1	Very low	31.9	Very low	194 Å²	194	140.2 Å²	140.2	84%	0.843	76%	0.757	S	S	*	*			cis	-165.1	144.3	38.6	-132	142.4	-169.7	-177.2	0	111.5
36	K	30.2	Very low	31.7	Very low	170 Å²	170	138.1 Å²	138.1	74%	0.739	75%	0.753	S	S	*	*			trans	-65.6	144.4	166	-166.1	-173.1	-174.2	-154	0	110.6	E38	K36-E38 IonicContact NZ-OE1 3.33Å; K36-E38 PolarHBondContact NZ-OE1 2.87Å
37	S	35.4	Very low	31.7	Very low	124 Å²	124	141.8 Å²	141.8	87%	0.867	76%	0.76	S	S	*	*			trans	-131.8	107.4	155.9	-167	0	0	0	0	109.5
38	E	31.7	Very low	31.2	Very low	137 Å²	137	145.3 Å²	145.3	64%	0.64	77%	0.765	S	S	*	*			trans	-45.9	163.3	144.1	-79.1	160.4	-165.3	0	0	110.6	K36	K36-E38 IonicContact NZ-OE1 3.33Å; K36-E38 PolarHBondContact NZ-OE1 2.87Å
39	D	29	Very low	31.5	Very low	134 Å²	134	145.8 Å²	145.8	72%	0.717	76%	0.758	S	S	*	*			cis	-178.3	-177.5	3.9	170.3	36.2	0	0	0	104.6
40	L	30.3	Very low	31.7	Very low	147 Å²	147	141.9 Å²	141.9	77%	0.77	75%	0.752	S	S	*	*			trans	100	133.6	158.6	-51.5	171	0	0	0	116.2
41	S	30.1	Very low	31.6	Very low	84 Å²	84	140.3 Å²	140.3	59%	0.587	75%	0.748	S	S	*	*			cis	168.7	139.4	-12.5	144.4	0	0	0	0	107.8
42	L	32	Very low	31.6	Very low	146 Å²	146	139.4 Å²	139.4	76%	0.764	75%	0.753	S	S	*	*			trans	74.4	110.1	147	-66	169.4	0	0	0	123.3
43	R	29.4	Very low	31.4	Very low	207 Å²	207	143.4 Å²	143.4	78%	0.781	76%	0.76	S	S	*	*				35.3	135.3	113.3	-66.1	-172.7	176.8	-126.1	-0.1	121.1
44	N	30.4	Very low	31.3	Very low	143 Å²	143	139.7 Å²	139.7	77%	0.765	76%	0.758	S	S	*	*				169.8	120.9	111.2	-81.9	-36.9	0	0	0	109
45	V	31.3	Very low	31.2	Very low	127 Å²	127	140.9 Å²	140.9	77%	0.77	77%	0.767	S	S	*	*				62.9	116.5	82.2	-179	0	0	0	0	115.1
46	A	30.6	Very low	31.1	Very low	86 Å²	86	138.3 Å²	138.3	71%	0.711	77%	0.767	S	S	*	*			trans	165.7	104.1	136.7	0	0	0	0	0	108
47	E	36.3	Very low	31.1	Very low	175 Å²	175	140.5 Å²	140.5	82%	0.818	77%	0.771	S	S	*	*				40.7	122.6	90.9	-76.1	-171.9	172.2	0	0	114.9
48	H	31.9	Very low	31.1	Very low	193 Å²	193	144 Å²	144	89%	0.894	77%	0.771	S	S	*	*				-171.3	146.1	124.9	-97.5	-74.5	0	0	0	111.8
49	S	32.6	Very low	31.2	Very low	80 Å²	80	145.8 Å²	145.8	56%	0.559	78%	0.779	S	S	*	*			trans	-96.3	158.9	-163.2	51	0	0	0	0	114.9
50	N	32.5	Very low	31.6	Very low	137 Å²	137	149.1 Å²	149.1	73%	0.733	79%	0.79	S	S	*	*				150.6	117.1	119.6	-75.6	-29.4	0	0	0	115.7
51	I	31	Very low	31.6	Very low	149 Å²	149	145.6 Å²	145.6	76%	0.764	79%	0.789	S	S	*	*				30.2	127.5	123.4	-53.1	171.1	0	0	0	119.3
52	T	28.6	Very low	32.2	Very low	135 Å²	135	146.4 Å²	146.4	83%	0.828	80%	0.801	S	S	*	*				178.2	142.7	114	-60.4	0	0	0	0	112
53	E	31.1	Very low	32.2	Very low	190 Å²	190	148.1 Å²	148.1	89%	0.888	81%	0.805	S	S	*	*			trans	-71	155.9	-171.3	-61.8	172.5	132.3	0	0	117.3
54	G	28	Very low	32.9	Very low	77 Å²	77	143.9 Å²	143.9	79%	0.794	81%	0.807	S	S	*	*				103.2	106.1	122.8	0	0	0	0	0	119.2
55	S	30.1	Very low	33.2	Very low	124 Å²	124	142.9 Å²	142.9	87%	0.867	81%	0.806	S	S	*	*			trans	-176.7	122.2	133.2	-177.3	0	0	0	0	111.9
56	T	30.8	Very low	33.7	Very low	140 Å²	140	144.2 Å²	144.2	86%	0.859	80%	0.804	S	S	*	*			trans	-80	119.7	174.3	-47.2	0	0	0	0	110.4
57	R	29.3	Very low	33.6	Very low	215 Å²	215	148.7 Å²	148.7	81%	0.811	81%	0.81	S	S	*	*			trans	-147.8	111	155.1	-165.1	171.7	-176.5	166.1	-0.1	110.3	Q59	R57-Q59 PolarHBondContact O-N 2.86Å
58	K	35.3	Very low	33.5	Very low	199 Å²	199	145.8 Å²	145.8	87%	0.865	80%	0.798	S	S	*	*			trans	-60.7	124.4	167.3	-71.5	-178.7	173.1	-174	0	109.4
59	Q	33.5	Very low	33.6	Very low	173 Å²	173	143.3 Å²	143.3	81%	0.808	79%	0.791	S	S	*	*			trans	-141.3	118.1	146.2	-76.2	-162.2	-79.7	0	0	108.2	R57	R57-Q59 PolarHBondContact O-N 2.86Å
60	E	37.5	Very low	33.5	Very low	205 Å²	205	147 Å²	147	96%	0.958	80%	0.799	S	S	*	*			trans	-62.7	136.4	162.8	-73.8	166.3	136.2	0	0	109.2
61	G	30.3	Very low	33.6	Very low	73 Å²	73	148.1 Å²	148.1	75%	0.753	80%	0.8	S	S	*	*			trans	166.9	83.5	175.4	0	0	0	0	0	112.1
62	A	43.9	Very low	33.7	Very low	101 Å²	101	149 Å²	149	84%	0.835	80%	0.801	S	S	*	*			trans	38.6	102.5	155.1	0	0	0	0	0	117.5
63	Q	31.4	Very low	34.3	Very low	181 Å²	181	147 Å²	147	85%	0.846	80%	0.798	S	S	*	*			trans	-140.9	122.2	149.7	-107.5	166.1	18.2	0	0	109.5	V65	Q63-V65 PolarHBondContact O-N 2.75Å; Q63-V65 VanDerWaalsContact O-N 3.13Å
64	S	44.9	Very low	35.1	Very low	118 Å²	118	145.2 Å²	145.2	83%	0.825	79%	0.79	S	S	*	*			trans	-45	109.2	164.4	51.3	0	0	0	0	110.3
65	V	35.2	Very low	36.4	Very low	122 Å²	122	149.9 Å²	149.9	74%	0.739	79%	0.791	S	S	*	*			trans	-118.1	93.9	155.5	-178.2	0	0	0	0	100.5	Q63 E67	Q63-V65 PolarHBondContact O-N 2.75Å; Q63-V65 VanDerWaalsContact O-N 3.13Å; V65-E67 PolarHBondContact O-N 2.74Å
66	E	42	Very low	38.3	Very low	156 Å²	156	148.5 Å²	148.5	73%	0.729	77%	0.771	S	S	*	*				43.9	52.7	88.9	-156.1	133.4	-148.7	0	0	109	M68	E66-M68 HydrophobicContact CG-CB 4.4Å; E66-M68 HydrophobicContact CG-CG 3.78Å; E66-M68 HydrophobicContact CG-SD 4.31Å; E66-M68 PolarHBondContact O-N 2.77Å
67	E	30.1	Very low	41	Very low	179 Å²	179	146.2 Å²	146.2	84%	0.836	76%	0.756	S	S	*	*			trans	-61.6	72.7	137.3	-80.1	-179.4	163.5	0	0	105.7	V65 L69	V65-E67 PolarHBondContact O-N 2.74Å; E67-L69 PolarHBondContact O-N 2.87Å
68	M	33.7	Very low	44	Very low	115 Å²	115	136.2 Å²	136.2	57%	0.567	72%	0.718	S	S	*	*			trans	-44.5	99.6	137.9	-91.9	172.6	41.9	0	0	103.8	E66 E70	E66-M68 HydrophobicContact CG-CB 4.4Å; E66-M68 HydrophobicContact CG-CG 3.78Å; E66-M68 HydrophobicContact CG-SD 4.31Å; E66-M68 PolarHBondContact O-N 2.77Å; M68-E70 HydrophobicContact CE-CG 3.94Å; M68-E70 PolarHBondContact O-N 2.65Å
69	L	32.8	Very low	46.8	Very low	141 Å²	141	128.2 Å²	128.2	74%	0.738	69%	0.685	S	S	*	*			trans	-54.5	88.9	146.9	-63.9	171.5	0	0	0	103.7	E67 E71	E67-L69 PolarHBondContact O-N 2.87Å; L69-E71 HydrophobicContact CB-CG 4.34Å; L69-E71 PolarHBondContact O-N 3.32Å
70	E	31.6	Very low	49.8	Very low	157 Å²	157	121 Å²	121	73%	0.734	65%	0.651	S	S	*	*			trans	-57.4	69	141.7	-67.3	175.7	167.2	0	0	104.8	M68 E72	M68-E70 HydrophobicContact CE-CG 3.94Å; M68-E70 PolarHBondContact O-N 2.65Å; E70-E72 PolarHBondContact O-N 3.26Å
71	E	34.6	Very low	52.6	Low	161 Å²	161	111.2 Å²	111.2	75%	0.752	61%	0.605	S	S	*	*			trans	-54.6	95.3	140.2	-76.2	-175.8	175.6	0	0	101.7	L69 A73	L69-E71 HydrophobicContact CB-CG 4.34Å; L69-E71 PolarHBondContact O-N 3.32Å; E71-A73 PolarHBondContact O-N 3.4Å
72	E	33	Very low	55.8	Low	167 Å²	167	107.8 Å²	107.8	78%	0.78	57%	0.57	S	S	*	*			trans	-37.4	104.8	154.9	-73.4	178.4	151.7	0	0	103.9	E70 E74	E70-E72 PolarHBondContact O-N 3.26Å; E72-E74 PolarHBondContact O-N 3.29Å
73	A	40.2	Very low	58.2	Low	93 Å²	93	103 Å²	103	77%	0.769	53%	0.53	S	S	*	.			trans	-68.9	79.9	176.3	0	0	0	0	0	103.7	E71 E75	E71-A73 PolarHBondContact O-N 3.4Å; A73-E75 VanDerWaalsContact C-N 3.33Å; A73-E75 PolarHBondContact O-N 2.86Å
74	E	47.9	Very low	61.2	Low	153 Å²	153	94.3 Å²	94.3	72%	0.715	49%	0.489	S	S	*	.			trans	-45.8	110.3	164.3	-75.4	-176.4	168	0	0	103.4	E72 E76	E72-E74 PolarHBondContact O-N 3.29Å; E74-E76 PolarHBondContact O-N 2.63Å
75	E	56.1	Low	63.5	Low	175 Å²	175	89.4 Å²	89.4	82%	0.818	45%	0.453	S	S	*	.			trans	-61.6	95	-173.6	-168.3	177.8	-156.4	0	0	105.8	A73 V77	A73-E75 VanDerWaalsContact C-N 3.33Å; A73-E75 PolarHBondContact O-N 2.86Å; E75-V77 WeakPolarHBondContact O-CG2 3.44Å; E75-V77 PolarHBondContact O-N 2.68Å
76	E	70.6	Confident	66.2	Low	95 Å²	95	83.7 Å²	83.7	44%	0.444	42%	0.419	S	S	.	.			trans	-58.4	111.4	-163.3	-163.5	174.9	124.2	0	0	108.4	E74 F78 W222 R226	E74-E76 PolarHBondContact O-N 2.63Å; E76-F78 PolarHBondContact O-N 3.18Å; E76-W222 HydrophobicContact CB-CH2 4.25Å; E76-W222 HydrophobicContact CB-CZ2 4.43Å; E76-W222 HydrophobicContact CG-CZ2 4.26Å; E76-W222 WeakPolarHBondContact O-CH2 3.4Å; E76-R226 IonicContact OE1-CZ 2.69Å; E76-R226 IonicContact OE1-NH1 2.66Å; E76-R226 PolarHBondContact OE1-NH1 2.69Å; E76-R226 IonicContact OE2-CZ 2.7Å; E76-R226 IonicContact OE2-NH1 3.79Å; E76-R226 PolarHBondContact OE2-NH1 3.2Å; E76-R226 IonicContact OE2-NH2 3.09Å; E76-R226 PolarHBondContact OE2-NH2 3.32Å
77	V	86.7	Confident	68.4	Low	92 Å²	92	84.3 Å²	84.3	56%	0.558	42%	0.422	S	S	*	.			trans	-84.6	122.2	-167.5	-178.8	0	0	0	0	108.3	E75 L79 P108	E75-V77 WeakPolarHBondContact O-CG2 3.44Å; E75-V77 PolarHBondContact O-N 2.68Å; V77-L79 PolarHBondContact O-N 3.33Å; V77-L79 VanDerWaalsContact O-N 3.15Å; V77-P108 HydrophobicContact CG1-CG 3.8Å
78	F	92.1	Very high	71.3	Confident	4 Å²	4	82 Å²	82	2%	0.018	42%	0.416	C	S	.	.			trans	-71.7	109.9	170.2	-173.1	-109	0	0	0	110.4	E76 G131 A133 Y215 Q218 Q219 W222	E76-F78 PolarHBondContact O-N 3.18Å; F78-G131 WeakPolarHBondContact CD2-O 3.47Å; F78-A133 HydrophobicContact CE1-CB 3.93Å; F78-A133 HydrophobicContact CZ-CB 4.04Å; F78-Y215 HydrophobicContact CD1-CD2 4.13Å; F78-Y215 AromaticContact CD1-CE2 3.43Å; F78-Y215 HydrophobicContact CD1-CE2 3.43Å; F78-Y215 VanDerWaalsContact CD1-CE2 3.43Å; F78-Y215 AromaticContact CD1-CZ 3.97Å; F78-Y215 AromaticContact CE1-CD2 3.89Å; F78-Y215 HydrophobicContact CE1-CD2 3.89Å; F78-Y215 AromaticContact CE1-CE2 3.67Å; F78-Y215 HydrophobicContact CE1-CE2 3.67Å; F78-Y215 PolarHBondContact O-OH 2.93Å; F78-Q218 HydrophobicContact CE1-CB 4.11Å; F78-Q218 HydrophobicContact CZ-CB 3.85Å; F78-Q219 HydrophobicContact CB-CG 4.19Å; F78-Q219 HydrophobicContact CD1-CB 3.5Å; F78-Q219 VanDerWaalsContact CD1-CB 3.5Å; F78-Q219 HydrophobicContact CD1-CG 3.71Å; F78-Q219 HydrophobicContact CE1-CB 3.77Å; F78-Q219 HydrophobicContact CE1-CG 4.47Å; F78-Q219 HydrophobicContact CG-CB 4.33Å; F78-Q219 HydrophobicContact CG-CG 4.18Å; F78-W222 HydrophobicContact CB-CD2 4.13Å; F78-W222 HydrophobicContact CB-CE3 3.73Å; F78-W222 HydrophobicContact CB-CH2 4.47Å; F78-W222 HydrophobicContact CB-CZ3 3.92Å; F78-W222 HydrophobicContact CD2-CB 3.83Å; F78-W222 AromaticContact CD2-CD1 3.79Å; F78-W222 AromaticContact CD2-CD2 3.53Å; F78-W222 HydrophobicContact CD2-CD2 3.53Å; F78-W222 AromaticContact CD2-CE3 3.98Å; F78-W222 HydrophobicContact CD2-CE3 3.98Å; F78-W222 AromaticContact CD2-CG 3.43Å; F78-W222 HydrophobicContact CD2-CG 3.43Å; F78-W222 VanDerWaalsContact CD2-CG 3.43Å; F78-W222 HydrophobicContact CE2-CB 3.78Å; F78-W222 AromaticContact CE2-CD1 3.93Å; F78-W222 HydrophobicContact CE2-CD2 4.31Å; F78-W222 AromaticContact CE2-CG 3.73Å; F78-W222 HydrophobicContact CE2-CG 3.73Å; F78-W222 HydrophobicContact CG-CD2 4.12Å; F78-W222 HydrophobicContact CG-CE3 4.09Å; F78-W222 HydrophobicContact CG-CG 4.32Å; F78-W222 HydrophobicContact CZ-CB 4.46Å
79	L	95.1	Very high	74.1	Confident	31 Å²	31	77.2 Å²	77.2	16%	0.162	39%	0.392	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-74.8	148.1	-175	-60.2	173.1	0	0	0	111	V77 P108 I110 G131 S132 A133	V77-L79 PolarHBondContact O-N 3.33Å; V77-L79 VanDerWaalsContact O-N 3.15Å; L79-P108 HydrophobicContact CD2-CB 4.09Å; L79-P108 HydrophobicContact CD2-CG 4.11Å; L79-I110 HydrophobicContact CD1-CB 4.16Å; L79-I110 HydrophobicContact CD1-CG2 3.49Å; L79-I110 VanDerWaalsContact CD1-CG2 3.49Å; L79-G131 PolarHBondContact N-O 3.13Å; L79-S132 CarbonylContact O-C 3.52Å; L79-S132 VanDerWaalsContact O-CA 3.28Å; L79-S132 WeakPolarHBondContact O-CA 3.29Å; L79-A133 PolarHBondContact O-N 3.07Å
80	K	96.1	Very high	77	Confident	22 Å²	22	72.5 Å²	72.5	10%	0.096	37%	0.369	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-66.7	-53.6	166	-73.9	-161.1	174.6	-168.1	0	109.1	I106 K107 P108 A133 W134 E212 Y215	K80-I106 HydrophobicContact CB-CG2 4.11Å; K80-I106 HydrophobicContact CD-CG2 3.89Å; K80-K107 WeakPolarHBondContact CD-O 3.37Å; K80-K107 WeakPolarHBondContact CE-O 3.21Å; K80-K107 WeakPolarHBondContact CG-O 3.25Å; K80-P108 WeakPolarHBondContact CB-O 3.3Å; K80-P108 PolarHBondContact N-O 3.4Å; K80-A133 WeakPolarHBondContact O-CA 3.11Å; K80-A133 WeakPolarHBondContact O-CB 3.46Å; K80-A133 PolarHBondContact O-N 3.11Å; K80-W134 HydrophobicContact CB-CE3 4.42Å; K80-W134 HydrophobicContact CB-CZ3 4.23Å; K80-W134 PolarHBondContact O-N 2.91Å; K80-E212 WeakPolarHBondContact CE-OE2 3.31Å; K80-E212 IonicContact NZ-OE2 3.07Å; K80-E212 PolarHBondContact NZ-OE2 3.33Å; K80-Y215 HydrophobicContact CB-CD2 4.41Å; K80-Y215 HydrophobicContact CB-CE2 4.38Å; K80-Y215 HydrophobicContact CG-CD2 3.71Å; K80-Y215 HydrophobicContact CG-CE2 3.61Å; K80-Y215 HydrophobicContact CG-CG 4.25Å
81	F	96.9	Very high	80.1	Confident	0 Å²	0	71.5 Å²	71.5	0%	0	37%	0.369	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-139.9	159.2	179.1	67.1	-99.8	0	0	0	113.5	I83 Q97 L100 Q101 I106 G109 I110 W134 I136	F81-I83 HydrophobicContact CD2-CD1 4.35Å; F81-I83 HydrophobicContact CD2-CG1 3.77Å; F81-I83 HydrophobicContact CE2-CD1 3.81Å; F81-I83 HydrophobicContact CE2-CG1 3.72Å; F81-Q97 HydrophobicContact CE2-CG 4.32Å; F81-Q97 HydrophobicContact CZ-CG 4.33Å; F81-L100 HydrophobicContact CD1-CD1 4.49Å; F81-L100 HydrophobicContact CE1-CB 3.78Å; F81-L100 HydrophobicContact CE1-CD1 4.04Å; F81-L100 HydrophobicContact CE2-CD1 4.3Å; F81-L100 HydrophobicContact CZ-CB 3.85Å; F81-L100 HydrophobicContact CZ-CD1 3.95Å; F81-Q101 HydrophobicContact CE1-CG 4.32Å; F81-Q101 HydrophobicContact CZ-CG 4.08Å; F81-I106 HydrophobicContact CD1-CB 4.46Å; F81-I106 HydrophobicContact CD1-CG2 3.69Å; F81-I106 HydrophobicContact CE1-CB 4.17Å; F81-I106 HydrophobicContact CE1-CG2 3.9Å; F81-I106 WeakPolarHBondContact CE1-O 3.48Å; F81-G109 WeakPolarHBondContact O-CA 3.32Å; F81-I110 PolarHBondContact O-N 3Å; F81-W134 CarbonylContact C-O 3.6Å; F81-W134 WeakPolarHBondContact CA-O 3.31Å; F81-W134 HydrophobicContact CB-CB 4.29Å; F81-I136 HydrophobicContact CB-CD1 3.98Å; F81-I136 HydrophobicContact CB-CG1 4.31Å; F81-I136 HydrophobicContact CD1-CD1 4.5Å; F81-I136 HydrophobicContact CD2-CD1 3.84Å; F81-I136 HydrophobicContact CE2-CD1 4.48Å; F81-I136 HydrophobicContact CG-CD1 3.86Å
82	V	96.1	Very high	83	Confident	0 Å²	0	64.9 Å²	64.9	0%	0	34%	0.338	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122	140.2	161.8	65.2	0	0	0	0	109.8	L84 I110 A128 S132 W134 T135 I136	V82-L84 HydrophobicContact CG1-CD2 4.5Å; V82-L84 HydrophobicContact CG2-CD2 4.29Å; V82-I110 CarbonylContact C-O 3.57Å; V82-I110 VanDerWaalsContact CA-O 3.31Å; V82-I110 WeakPolarHBondContact CA-O 3.39Å; V82-I110 HydrophobicContact CB-CG2 4.37Å; V82-I110 HydrophobicContact CG2-CG2 3.92Å; V82-A128 HydrophobicContact CG1-CB 4.37Å; V82-A128 HydrophobicContact CG2-CB 4.2Å; V82-S132 WeakPolarHBondContact CG1-OG 3.13Å; V82-W134 PolarHBondContact N-O 3.32Å; V82-T135 HydrophobicContact CG1-CG2 4.1Å; V82-I136 PolarHBondContact O-N 3.27Å
83	I	95.9	Very high	86	Confident	0 Å²	0	57 Å²	57	0%	0	30%	0.301	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-101.7	122	173.9	-52.7	-178.3	0	0	0	109.5	F81 A93 V96 Q97 I110 I111 F112 I136 L138	F81-I83 HydrophobicContact CD2-CD1 4.35Å; F81-I83 HydrophobicContact CD2-CG1 3.77Å; F81-I83 HydrophobicContact CE2-CD1 3.81Å; F81-I83 HydrophobicContact CE2-CG1 3.72Å; I83-A93 HydrophobicContact CG2-CB 4.18Å; I83-V96 HydrophobicContact CD1-CB 4.26Å; I83-V96 HydrophobicContact CD1-CG1 3.95Å; I83-Q97 HydrophobicContact CD1-CB 4Å; I83-I110 PolarHBondContact N-O 3.09Å; I83-I111 HydrophobicContact CB-CG2 4.2Å; I83-I111 HydrophobicContact CD1-CG2 4.35Å; I83-F112 PolarHBondContact O-N 3.15Å; I83-I136 WeakPolarHBondContact CA-O 3.41Å; I83-I136 HydrophobicContact CG1-CB 4.18Å; I83-I136 HydrophobicContact CG1-CD1 4.3Å; I83-L138 HydrophobicContact CG2-CB 4.15Å
84	L	93.7	Very high	88.7	Confident	0 Å²	0	54.9 Å²	54.9	0%	0	28%	0.277	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.5	127	169	-50.2	-172.1	0	0	0	108.5	V82 F112 L125 T135 I136 L137 L138 F143 Q152 S156	V82-L84 HydrophobicContact CG1-CD2 4.5Å; V82-L84 HydrophobicContact CG2-CD2 4.29Å; L84-F112 HydrophobicContact CD2-CB 3.78Å; L84-F112 HydrophobicContact CD2-CD2 3.99Å; L84-F112 HydrophobicContact CD2-CG 3.96Å; L84-L125 HydrophobicContact CD1-CD1 3.92Å; L84-L125 HydrophobicContact CD2-CD1 4.11Å; L84-T135 HydrophobicContact CD1-CG2 3.66Å; L84-T135 HydrophobicContact CG-CG2 3.84Å; L84-I136 PolarHBondContact N-O 3.38Å; L84-L137 HydrophobicContact CB-CD2 4.02Å; L84-L137 HydrophobicContact CD1-CD2 3.7Å; L84-L137 HydrophobicContact CG-CD2 4.14Å; L84-L138 WeakPolarHBondContact O-CB 3.44Å; L84-L138 PolarHBondContact O-N 3.21Å; L84-F143 HydrophobicContact CB-CE2 4.41Å; L84-Q152 HydrophobicContact CD1-CB 4.07Å; L84-S156 VanDerWaalsContact CD1-OG 3.27Å; L84-S156 WeakPolarHBondContact CD1-OG 3.31Å
85	H	92.9	Very high	91.1	Very high	14 Å²	14	51 Å²	51	7%	0.065	26%	0.256	C	S	.	.			trans	-143	161.6	-176.1	64.6	91.3	0	0	0	110.1	T90 A93 L138	H85-T90 PolarHBondContact CE1-OG1 3Å; H85-T90 VanDerWaalsContact CE1-OG1 3.24Å; H85-A93 HydrophobicContact CB-CB 3.89Å; H85-L138 HydrophobicContact CB-CB 4.1Å; H85-L138 HydrophobicContact CB-CD2 3.86Å
86	A	91.5	Very high	93	Very high	3 Å²	3	42.8 Å²	42.8	3%	0.025	22%	0.217	C	C	.	.			trans	-72.3	153.2	167.5	0	0	0	0	0	110.2	D88 D89 N142 C149	A86-D88 PolarHBondContact O-N 3.26Å; A86-D89 PolarHBondContact O-N 3.47Å; A86-N142 HydrophobicContact CB-CB 3.94Å; A86-C149 VanDerWaalsContact CA-SG 3.59Å
87	E	88.9	Confident	94.3	Very high	168 Å²	168	38.9 Å²	38.9	79%	0.785	20%	0.199	S	C	*	.	G	3₁₀ helix	trans	-52.4	-41	179.3	-171.1	175.7	179.9	0	0	112	D89 T90	E87-D89 PolarHBondContact O-N 3.15Å; E87-T90 PolarHBondContact O-N 3.24Å; E87-T90 PolarHBondContact O-OG1 3.02Å
88	D	90.5	Very high	94.8	Very high	132 Å²	132	38.2 Å²	38.2	71%	0.706	19%	0.192	S	C	*	.	G	3₁₀ helix	trans	-67.6	-15.6	179.5	-64	-38.4	0	0	0	114.5	A86 N142	A86-D88 PolarHBondContact O-N 3.26Å; D88-N142 HydrophobicContact CB-CB 4.5Å
89	D	93.3	Very high	95	Very high	14 Å²	14	39.3 Å²	39.3	8%	0.075	20%	0.198	C	C	.	.	G	3₁₀ helix	trans	-109.2	19.5	-175.6	-53.8	-49.2	0	0	0	113.1	A86 E87 D91 E92 A93 L138 T140 N142	A86-D89 PolarHBondContact O-N 3.47Å; E87-D89 PolarHBondContact O-N 3.15Å; D89-D91 VanDerWaalsContact C-N 3.29Å; D89-D91 PolarHBondContact O-N 3.42Å; D89-E92 PolarHBondContact O-N 3.4Å; D89-E92 VanDerWaalsContact O-N 3.14Å; D89-A93 PolarHBondContact O-N 2.83Å; D89-L138 HydrophobicContact CB-CD2 4.28Å; D89-T140 HydrophobicContact CB-CG2 4.15Å; D89-T140 VanDerWaalsContact OD2-CB 3.27Å; D89-T140 WeakPolarHBondContact OD2-CB 3.41Å; D89-T140 WeakPolarHBondContact OD2-CG2 3.24Å; D89-T140 PolarHBondContact OD2-OG1 2.98Å; D89-N142 PolarHBondContact OD1-ND2 2.94Å; D89-N142 WeakPolarHBondContact OD2-CB 3.47Å
90	T	94	Very high	95.1	Very high	41 Å²	41	37.9 Å²	37.9	25%	0.252	19%	0.191	S	C	.	.	H	α-helix	trans	-54.8	-44	-179	-59.3	0	0	0	0	112.1	H85 E87 E92 A93 L94 I111	H85-T90 PolarHBondContact CE1-OG1 3Å; H85-T90 VanDerWaalsContact CE1-OG1 3.24Å; E87-T90 PolarHBondContact O-N 3.24Å; E87-T90 PolarHBondContact O-OG1 3.02Å; T90-E92 VanDerWaalsContact C-N 3.33Å; T90-E92 PolarHBondContact O-N 3.14Å; T90-A93 WeakPolarHBondContact O-CB 3.5Å; T90-A93 PolarHBondContact O-N 3.29Å; T90-L94 HydrophobicContact CG2-CD1 4.37Å; T90-L94 WeakPolarHBondContact O-CG 3.46Å; T90-L94 PolarHBondContact O-N 3.44Å; T90-I111 HydrophobicContact CG2-CD1 3.9Å
91	D	95.4	Very high	95.2	Very high	137 Å²	137	38.6 Å²	38.6	73%	0.733	19%	0.194	S	C	*	.	H	α-helix	trans	-63	-39.1	179.4	-66.7	-29.8	0	0	0	112.4	D89 L94 R95	D89-D91 VanDerWaalsContact C-N 3.29Å; D89-D91 PolarHBondContact O-N 3.42Å; D91-L94 PolarHBondContact O-N 3.47Å; D91-R95 WeakPolarHBondContact O-CB 3.38Å; D91-R95 PolarHBondContact O-N 3.28Å
92	E	96.3	Very high	95.1	Very high	22 Å²	22	44.4 Å²	44.4	10%	0.103	23%	0.225	C	C	.	.	H	α-helix	trans	-70.7	-37.2	177.7	-172.8	63.1	-172.4	0	0	110.9	D89 T90 R95 V96 L138 P175 N177	D89-E92 PolarHBondContact O-N 3.4Å; D89-E92 VanDerWaalsContact O-N 3.14Å; T90-E92 VanDerWaalsContact C-N 3.33Å; T90-E92 PolarHBondContact O-N 3.14Å; E92-R95 VanDerWaalsContact CD-NE 3.35Å; E92-R95 WeakPolarHBondContact O-CB 3.45Å; E92-R95 PolarHBondContact O-N 3.44Å; E92-R95 IonicContact OE1-CZ 3.03Å; E92-R95 VanDerWaalsContact OE1-CZ 3.29Å; E92-R95 IonicContact OE1-NE 2.89Å; E92-R95 PolarHBondContact OE1-NE 2.9Å; E92-R95 VanDerWaalsContact OE1-NE 3.09Å; E92-R95 IonicContact OE1-NH2 2.7Å; E92-R95 PolarHBondContact OE1-NH2 3.36Å; E92-R95 IonicContact OE2-CZ 3.79Å; E92-R95 IonicContact OE2-NE 2.98Å; E92-R95 PolarHBondContact OE2-NE 3.48Å; E92-V96 WeakPolarHBondContact O-CG2 3.14Å; E92-V96 PolarHBondContact O-N 3.27Å; E92-L138 HydrophobicContact CB-CD2 4.37Å; E92-L138 HydrophobicContact CG-CD2 4.27Å; E92-P175 HydrophobicContact CG-CB 3.89Å; E92-P175 HydrophobicContact CG-CG 4.28Å; E92-P175 WeakPolarHBondContact OE1-CB 3.31Å; E92-N177 PolarHBondContact OE1-ND2 3.06Å; E92-N177 PolarHBondContact OE2-ND2 2.94Å
93	A	96.2	Very high	95.1	Very high	0 Å²	0	50.1 Å²	50.1	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-62.5	-44.1	173.9	0	0	0	0	0	111.8	I83 H85 D89 T90 V96 Q97 I111 L138	I83-A93 HydrophobicContact CG2-CB 4.18Å; H85-A93 HydrophobicContact CB-CB 3.89Å; D89-A93 PolarHBondContact O-N 2.83Å; T90-A93 WeakPolarHBondContact O-CB 3.5Å; T90-A93 PolarHBondContact O-N 3.29Å; A93-V96 PolarHBondContact O-N 3.12Å; A93-Q97 WeakPolarHBondContact O-CB 3.44Å; A93-Q97 PolarHBondContact O-N 3Å; A93-I111 HydrophobicContact CB-CB 4.43Å; A93-I111 HydrophobicContact CB-CG2 3.82Å; A93-L138 HydrophobicContact CB-CD2 4.02Å
94	L	96.9	Very high	95.1	Very high	50 Å²	50	52.9 Å²	52.9	26%	0.262	27%	0.268	S	S	.	.	H	α-helix	trans	-62.2	-41.9	174.5	-70.7	173.9	0	0	0	111.7	T90 D91 V96 Q97 N98 I111 E114	T90-L94 HydrophobicContact CG2-CD1 4.37Å; T90-L94 WeakPolarHBondContact O-CG 3.46Å; T90-L94 PolarHBondContact O-N 3.44Å; D91-L94 PolarHBondContact O-N 3.47Å; L94-V96 PolarHBondContact O-N 3.05Å; L94-Q97 WeakPolarHBondContact O-CB 3.37Å; L94-Q97 PolarHBondContact O-N 2.84Å; L94-N98 VanDerWaalsContact O-CG 3.3Å; L94-N98 PolarHBondContact O-N 3.05Å; L94-N98 PolarHBondContact O-ND2 3.3Å; L94-I111 HydrophobicContact CD2-CD1 3.55Å; L94-I111 HydrophobicContact CD2-CG1 4.15Å; L94-I111 HydrophobicContact CD2-CG2 4.41Å; L94-I111 HydrophobicContact CG-CD1 3.85Å; L94-E114 VanDerWaalsContact CD2-OE1 3.29Å; L94-E114 WeakPolarHBondContact CD2-OE1 3.47Å
95	R	97.3	Very high	95.3	Very high	72 Å²	72	54.7 Å²	54.7	27%	0.272	29%	0.287	S	S	.	.	H	α-helix	trans	-60	-46	176	-169.7	-165.2	67.6	72.2	1.4	111.4	D91 E92 N98 L99 E197	D91-R95 WeakPolarHBondContact O-CB 3.38Å; D91-R95 PolarHBondContact O-N 3.28Å; E92-R95 VanDerWaalsContact CD-NE 3.35Å; E92-R95 WeakPolarHBondContact O-CB 3.45Å; E92-R95 PolarHBondContact O-N 3.44Å; E92-R95 IonicContact OE1-CZ 3.03Å; E92-R95 VanDerWaalsContact OE1-CZ 3.29Å; E92-R95 IonicContact OE1-NE 2.89Å; E92-R95 PolarHBondContact OE1-NE 2.9Å; E92-R95 VanDerWaalsContact OE1-NE 3.09Å; E92-R95 IonicContact OE1-NH2 2.7Å; E92-R95 PolarHBondContact OE1-NH2 3.36Å; E92-R95 IonicContact OE2-CZ 3.79Å; E92-R95 IonicContact OE2-NE 2.98Å; E92-R95 PolarHBondContact OE2-NE 3.48Å; R95-N98 PolarHBondContact O-N 2.86Å; R95-L99 WeakPolarHBondContact O-CB 3.29Å; R95-L99 PolarHBondContact O-N 3.42Å; R95-E197 IonicContact CZ-OE1 3.55Å; R95-E197 IonicContact CZ-OE2 2.63Å; R95-E197 IonicContact NH1-OE1 3.83Å; R95-E197 PolarHBondContact NH1-OE1 3.19Å; R95-E197 IonicContact NH1-OE2 2.83Å; R95-E197 VanDerWaalsContact NH2-CD 3.27Å; R95-E197 IonicContact NH2-OE1 3.05Å; R95-E197 PolarHBondContact NH2-OE1 2.75Å; R95-E197 VanDerWaalsContact NH2-OE1 3.07Å; R95-E197 IonicContact NH2-OE2 4Å; R95-E197 PolarHBondContact NH2-OE2 2.89Å
96	V	97.1	Very high	95.4	Very high	1 Å²	1	54.8 Å²	54.8	1%	0.006	29%	0.288	C	S	.	.	H	α-helix	trans	-67.5	-38	178.1	172.9	0	0	0	0	111.6	I83 E92 A93 L94 L99 L100 L138 M173	I83-V96 HydrophobicContact CD1-CB 4.26Å; I83-V96 HydrophobicContact CD1-CG1 3.95Å; E92-V96 WeakPolarHBondContact O-CG2 3.14Å; E92-V96 PolarHBondContact O-N 3.27Å; A93-V96 PolarHBondContact O-N 3.12Å; L94-V96 PolarHBondContact O-N 3.05Å; V96-L99 WeakPolarHBondContact O-CB 3.4Å; V96-L99 PolarHBondContact O-N 2.76Å; V96-L100 HydrophobicContact CG1-CD1 4.1Å; V96-L100 HydrophobicContact CG1-CG 4.43Å; V96-L100 WeakPolarHBondContact O-CG 3.46Å; V96-L100 PolarHBondContact O-N 3.24Å; V96-L138 HydrophobicContact CG2-CD1 4.2Å; V96-M173 HydrophobicContact CB-CE 4.26Å; V96-M173 HydrophobicContact CG1-CE 3.67Å; V96-M173 HydrophobicContact CG1-SD 4.12Å; V96-M173 HydrophobicContact CG2-CE 3.47Å; V96-M173 VanDerWaalsContact CG2-CE 3.47Å; V96-M173 HydrophobicContact CG2-SD 4.15Å
97	Q	97.3	Very high	95.6	Very high	13 Å²	13	61.2 Å²	61.2	6%	0.061	32%	0.315	C	S	.	.	H	α-helix	trans	-58.8	-50.3	173.5	-180	-166.3	24	0	0	110.6	F81 I83 A93 L94 L99 L100 Q101 G109 I111 E114	F81-Q97 HydrophobicContact CE2-CG 4.32Å; F81-Q97 HydrophobicContact CZ-CG 4.33Å; I83-Q97 HydrophobicContact CD1-CB 4Å; A93-Q97 WeakPolarHBondContact O-CB 3.44Å; A93-Q97 PolarHBondContact O-N 3Å; L94-Q97 WeakPolarHBondContact O-CB 3.37Å; L94-Q97 PolarHBondContact O-N 2.84Å; Q97-L99 PolarHBondContact O-N 3.46Å; Q97-L100 PolarHBondContact O-N 2.9Å; Q97-Q101 WeakPolarHBondContact O-CB 3.36Å; Q97-Q101 VanDerWaalsContact O-CG 3.31Å; Q97-Q101 WeakPolarHBondContact O-CG 3.35Å; Q97-Q101 PolarHBondContact O-N 2.97Å; Q97-G109 PolarHBondContact NE2-O 2.9Å; Q97-I111 HydrophobicContact CB-CG2 4.19Å; Q97-E114 PolarHBondContact NE2-OE2 3.32Å
98	N	97	Very high	95.8	Very high	78 Å²	78	55.4 Å²	55.4	42%	0.417	29%	0.292	S	S	.	.	H	α-helix	trans	-61.7	-44.2	177.9	-68	-27.9	0	0	0	111.3	L94 R95 L100 Q101 D102	L94-N98 VanDerWaalsContact O-CG 3.3Å; L94-N98 PolarHBondContact O-N 3.05Å; L94-N98 PolarHBondContact O-ND2 3.3Å; R95-N98 PolarHBondContact O-N 2.86Å; N98-L100 PolarHBondContact O-N 3.12Å; N98-Q101 PolarHBondContact O-N 2.68Å; N98-D102 VanDerWaalsContact O-CB 3.25Å; N98-D102 WeakPolarHBondContact O-CB 2.99Å; N98-D102 PolarHBondContact O-N 3.44Å
99	L	97	Very high	96	Very high	27 Å²	27	49.5 Å²	49.5	14%	0.141	26%	0.263	C	S	.	.	I	π-helix	trans	-53.6	-51.3	174.4	174.8	66.7	0	0	0	111.8	R95 V96 Q97 D103 F104 E197 F202	R95-L99 WeakPolarHBondContact O-CB 3.29Å; R95-L99 PolarHBondContact O-N 3.42Å; V96-L99 WeakPolarHBondContact O-CB 3.4Å; V96-L99 PolarHBondContact O-N 2.76Å; Q97-L99 PolarHBondContact O-N 3.46Å; L99-D103 HydrophobicContact CD1-CB 4.2Å; L99-D103 VanDerWaalsContact CD1-OD2 3.29Å; L99-D103 WeakPolarHBondContact CD1-OD2 3.38Å; L99-D103 VanDerWaalsContact O-CB 3.31Å; L99-D103 WeakPolarHBondContact O-CB 3.28Å; L99-D103 PolarHBondContact O-N 3.14Å; L99-D103 VanDerWaalsContact O-N 3.12Å; L99-F104 HydrophobicContact CD1-CE2 4.05Å; L99-F104 HydrophobicContact CG-CE2 4.27Å; L99-F104 WeakPolarHBondContact O-CD2 3.26Å; L99-E197 HydrophobicContact CD2-CG 4.12Å; L99-E197 VanDerWaalsContact CD2-OE1 3.25Å; L99-E197 WeakPolarHBondContact CD2-OE1 3.32Å; L99-F202 HydrophobicContact CD2-CE1 3.84Å; L99-F202 HydrophobicContact CD2-CZ 3.71Å; L99-F202 HydrophobicContact CG-CE1 4.33Å; L99-F202 HydrophobicContact CG-CZ 4.41Å
100	L	97.4	Very high	96.1	Very high	1 Å²	1	50.5 Å²	50.5	1%	0.005	27%	0.267	C	S	.	.	I	π-helix	trans	-68.2	-37	-178.6	-68.6	174.4	0	0	0	112.6	F81 V96 Q97 N98 F104 G105 I106 I136 V206 F210	F81-L100 HydrophobicContact CD1-CD1 4.49Å; F81-L100 HydrophobicContact CE1-CB 3.78Å; F81-L100 HydrophobicContact CE1-CD1 4.04Å; F81-L100 HydrophobicContact CE2-CD1 4.3Å; F81-L100 HydrophobicContact CZ-CB 3.85Å; F81-L100 HydrophobicContact CZ-CD1 3.95Å; V96-L100 HydrophobicContact CG1-CD1 4.1Å; V96-L100 HydrophobicContact CG1-CG 4.43Å; V96-L100 WeakPolarHBondContact O-CG 3.46Å; V96-L100 PolarHBondContact O-N 3.24Å; Q97-L100 PolarHBondContact O-N 2.9Å; N98-L100 PolarHBondContact O-N 3.12Å; L100-F104 CarbonylContact O-C 3.55Å; L100-F104 WeakPolarHBondContact O-CB 3.45Å; L100-G105 PolarHBondContact O-N 3.45Å; L100-I106 HydrophobicContact CB-CB 4.47Å; L100-I106 WeakPolarHBondContact O-CB 3.15Å; L100-I106 PolarHBondContact O-N 2.85Å; L100-I136 HydrophobicContact CD1-CD1 3.47Å; L100-I136 VanDerWaalsContact CD1-CD1 3.47Å; L100-V206 HydrophobicContact CD2-CG1 4.28Å; L100-V206 HydrophobicContact CD2-CG2 4.17Å; L100-F210 HydrophobicContact CD1-CZ 4.48Å; L100-F210 HydrophobicContact CD2-CE2 4.14Å
101	Q	96.9	Very high	96.1	Very high	38 Å²	38	48.6 Å²	48.6	18%	0.178	26%	0.256	C	S	.	.	I	π-helix	trans	-77.8	-46.4	-177.7	-70.4	-166	116.5	0	0	112.9	F81 Q97 N98 G105 I106 K107 G109	F81-Q101 HydrophobicContact CE1-CG 4.32Å; F81-Q101 HydrophobicContact CZ-CG 4.08Å; Q97-Q101 WeakPolarHBondContact O-CB 3.36Å; Q97-Q101 VanDerWaalsContact O-CG 3.31Å; Q97-Q101 WeakPolarHBondContact O-CG 3.35Å; Q97-Q101 PolarHBondContact O-N 2.97Å; N98-Q101 PolarHBondContact O-N 2.68Å; Q101-G105 WeakPolarHBondContact O-CA 3.45Å; Q101-G105 PolarHBondContact O-N 3.3Å; Q101-G105 VanDerWaalsContact O-N 3.16Å; Q101-I106 WeakPolarHBondContact CG-O 3.15Å; Q101-K107 HydrophobicContact CG-CB 4.29Å; Q101-G109 PolarHBondContact OE1-O 3.3Å
102	D	96.5	Very high	95.8	Very high	121 Å²	121	43.4 Å²	43.4	65%	0.647	23%	0.227	S	C	*	.	I	π-helix	trans	-85.8	-46.4	-171	-62.7	-26	0	0	0	111.3	N98	N98-D102 VanDerWaalsContact O-CB 3.25Å; N98-D102 WeakPolarHBondContact O-CB 2.99Å; N98-D102 PolarHBondContact O-N 3.44Å
103	D	96	Very high	95.3	Very high	120 Å²	120	45.3 Å²	45.3	64%	0.642	25%	0.246	S	C	*	.	I	π-helix	trans	-84.7	-31.6	-174.4	-63.5	-4	0	0	0	112.1	L99	L99-D103 HydrophobicContact CD1-CB 4.2Å; L99-D103 VanDerWaalsContact CD1-OD2 3.29Å; L99-D103 WeakPolarHBondContact CD1-OD2 3.38Å; L99-D103 VanDerWaalsContact O-CB 3.31Å; L99-D103 WeakPolarHBondContact O-CB 3.28Å; L99-D103 PolarHBondContact O-N 3.14Å; L99-D103 VanDerWaalsContact O-N 3.12Å
104	F	96.1	Very high	94.6	Very high	58 Å²	58	49.8 Å²	49.8	25%	0.254	27%	0.267	S	S	.	.	S	Bend	trans	-111.7	-4.6	-177.7	-64	-84.5	0	0	0	114.4	L99 L100 I106 F202 P203 V206	L99-F104 HydrophobicContact CD1-CE2 4.05Å; L99-F104 HydrophobicContact CG-CE2 4.27Å; L99-F104 WeakPolarHBondContact O-CD2 3.26Å; L100-F104 CarbonylContact O-C 3.55Å; L100-F104 WeakPolarHBondContact O-CB 3.45Å; F104-I106 HydrophobicContact CB-CD1 4.41Å; F104-I106 HydrophobicContact CB-CG1 3.86Å; F104-I106 WeakPolarHBondContact O-CD1 3.48Å; F104-I106 PolarHBondContact O-N 2.78Å; F104-F202 HydrophobicContact CD2-CE1 4.49Å; F104-F202 HydrophobicContact CE2-CD1 4.18Å; F104-F202 AromaticContact CE2-CE1 3.46Å; F104-F202 HydrophobicContact CE2-CE1 3.46Å; F104-F202 VanDerWaalsContact CE2-CE1 3.46Å; F104-F202 HydrophobicContact CE2-CZ 4.27Å; F104-F202 AromaticContact CZ-CD1 3.86Å; F104-F202 HydrophobicContact CZ-CD1 3.86Å; F104-F202 AromaticContact CZ-CE1 3.61Å; F104-F202 HydrophobicContact CZ-CE1 3.61Å; F104-P203 HydrophobicContact CE1-CB 3.86Å; F104-P203 HydrophobicContact CE1-CG 4.35Å; F104-P203 HydrophobicContact CZ-CB 4.31Å; F104-P203 HydrophobicContact CZ-CG 4.32Å; F104-V206 HydrophobicContact CB-CG1 3.81Å; F104-V206 HydrophobicContact CD1-CB 4.01Å; F104-V206 HydrophobicContact CD1-CG1 3.63Å; F104-V206 HydrophobicContact CD1-CG2 4.4Å; F104-V206 HydrophobicContact CD2-CG1 4.35Å; F104-V206 HydrophobicContact CE1-CB 4.19Å; F104-V206 HydrophobicContact CE1-CG1 4.3Å; F104-V206 HydrophobicContact CE1-CG2 4.31Å; F104-V206 HydrophobicContact CG-CB 4.39Å; F104-V206 HydrophobicContact CG-CG1 3.66Å; F104-V206 HydrophobicContact CZ-CG2 4.37Å
105	G	96	Very high	93.4	Very high	39 Å²	39	48.8 Å²	48.8	40%	0.402	26%	0.261	S	S	.	.			trans	68.7	17.8	177.7	0	0	0	0	0	114.4	L100 Q101 K107	L100-G105 PolarHBondContact O-N 3.45Å; Q101-G105 WeakPolarHBondContact O-CA 3.45Å; Q101-G105 PolarHBondContact O-N 3.3Å; Q101-G105 VanDerWaalsContact O-N 3.16Å; G105-K107 VanDerWaalsContact C-N 3.31Å; G105-K107 PolarHBondContact O-N 2.94Å
106	I	96.5	Very high	91.9	Very high	15 Å²	15	50 Å²	50	8%	0.077	28%	0.278	C	S	.	.			trans	-82.8	76.7	-178.2	-47.1	-53.7	0	0	0	109.2	K80 F81 L100 Q101 F104 V206 F210	K80-I106 HydrophobicContact CB-CG2 4.11Å; K80-I106 HydrophobicContact CD-CG2 3.89Å; F81-I106 HydrophobicContact CD1-CB 4.46Å; F81-I106 HydrophobicContact CD1-CG2 3.69Å; F81-I106 HydrophobicContact CE1-CB 4.17Å; F81-I106 HydrophobicContact CE1-CG2 3.9Å; F81-I106 WeakPolarHBondContact CE1-O 3.48Å; L100-I106 HydrophobicContact CB-CB 4.47Å; L100-I106 WeakPolarHBondContact O-CB 3.15Å; L100-I106 PolarHBondContact O-N 2.85Å; Q101-I106 WeakPolarHBondContact CG-O 3.15Å; F104-I106 HydrophobicContact CB-CD1 4.41Å; F104-I106 HydrophobicContact CB-CG1 3.86Å; F104-I106 WeakPolarHBondContact O-CD1 3.48Å; F104-I106 PolarHBondContact O-N 2.78Å; I106-V206 HydrophobicContact CG1-CG1 4.19Å; I106-F210 HydrophobicContact CD1-CB 3.72Å; I106-F210 HydrophobicContact CD1-CG 4.36Å; I106-F210 HydrophobicContact CG1-CB 4.17Å; I106-F210 HydrophobicContact CG1-CD2 4.36Å; I106-F210 HydrophobicContact CG1-CG 4.27Å; I106-F210 HydrophobicContact CG2-CB 4.12Å; I106-F210 HydrophobicContact CG2-CD1 3.94Å; I106-F210 HydrophobicContact CG2-CG 4Å
107	K	94.5	Very high	90	Very high	138 Å²	138	56 Å²	56	60%	0.6	32%	0.319	S	S	*	.			trans	-123.7	151.6	179.2	63	-174	177.3	-173.8	0	112.9	K80 Q101 G105	K80-K107 WeakPolarHBondContact CD-O 3.37Å; K80-K107 WeakPolarHBondContact CE-O 3.21Å; K80-K107 WeakPolarHBondContact CG-O 3.25Å; Q101-K107 HydrophobicContact CG-CB 4.29Å; G105-K107 VanDerWaalsContact C-N 3.31Å; G105-K107 PolarHBondContact O-N 2.94Å
108	P	94.6	Very high	88	Confident	47 Å²	47	59 Å²	59	31%	0.305	35%	0.354	S	S	.	.	S	Bend	cis	-85.3	142.9	0.6	31.6	-31.2	0	0	0	112.9	V77 L79 K80	V77-P108 HydrophobicContact CG1-CG 3.8Å; L79-P108 HydrophobicContact CD2-CB 4.09Å; L79-P108 HydrophobicContact CD2-CG 4.11Å; K80-P108 WeakPolarHBondContact CB-O 3.3Å; K80-P108 PolarHBondContact N-O 3.4Å
109	G	94.4	Very high	86.3	Confident	8 Å²	8	62.5 Å²	62.5	8%	0.082	36%	0.361	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.1	149.9	174	0	0	0	0	0	112.2	F81 Q97 Q101	F81-G109 WeakPolarHBondContact O-CA 3.32Å; Q97-G109 PolarHBondContact NE2-O 2.9Å; Q101-G109 PolarHBondContact OE1-O 3.3Å
110	I	94.7	Very high	85.3	Confident	34 Å²	34	68.2 Å²	68.2	17%	0.174	39%	0.387	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-132.2	157	-176.7	-153.2	177.5	0	0	0	111.6	L79 F81 V82 I83 E114	L79-I110 HydrophobicContact CD1-CB 4.16Å; L79-I110 HydrophobicContact CD1-CG2 3.49Å; L79-I110 VanDerWaalsContact CD1-CG2 3.49Å; F81-I110 PolarHBondContact O-N 3Å; V82-I110 CarbonylContact C-O 3.57Å; V82-I110 VanDerWaalsContact CA-O 3.31Å; V82-I110 WeakPolarHBondContact CA-O 3.39Å; V82-I110 HydrophobicContact CB-CG2 4.37Å; V82-I110 HydrophobicContact CG2-CG2 3.92Å; I83-I110 PolarHBondContact N-O 3.09Å; I110-E114 HydrophobicContact CD1-CB 3.79Å; I110-E114 HydrophobicContact CG1-CB 3.76Å; I110-E114 WeakPolarHBondContact CG1-OE2 3.32Å
111	I	94.4	Very high	84.2	Confident	2 Å²	2	74.4 Å²	74.4	1%	0.01	42%	0.416	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.2	150.6	162.8	67	166.5	0	0	0	110.2	I83 T90 A93 L94 Q97 A113 E114	I83-I111 HydrophobicContact CB-CG2 4.2Å; I83-I111 HydrophobicContact CD1-CG2 4.35Å; T90-I111 HydrophobicContact CG2-CD1 3.9Å; A93-I111 HydrophobicContact CB-CB 4.43Å; A93-I111 HydrophobicContact CB-CG2 3.82Å; L94-I111 HydrophobicContact CD2-CD1 3.55Å; L94-I111 HydrophobicContact CD2-CG1 4.15Å; L94-I111 HydrophobicContact CD2-CG2 4.41Å; L94-I111 HydrophobicContact CG-CD1 3.85Å; Q97-I111 HydrophobicContact CB-CG2 4.19Å; I111-A113 HydrophobicContact CD1-CB 4.09Å; I111-A113 HydrophobicContact CG1-CB 4.45Å; I111-A113 PolarHBondContact O-N 3.08Å; I111-E114 HydrophobicContact CD1-CG 3.97Å; I111-E114 HydrophobicContact CG1-CB 3.99Å; I111-E114 HydrophobicContact CG1-CG 3.51Å; I111-E114 PolarHBondContact O-N 2.96Å; I111-E114 VanDerWaalsContact O-N 3.12Å
112	F	89.4	Confident	83.4	Confident	28 Å²	28	76.9 Å²	76.9	12%	0.123	43%	0.429	C	S	.	.	G	3₁₀ helix	trans	-60.6	-33.4	-177.1	-173.2	-108.8	0	0	0	113.2	I83 L84 E114 M115 N124 L125 A128 Q152	I83-F112 PolarHBondContact O-N 3.15Å; L84-F112 HydrophobicContact CD2-CB 3.78Å; L84-F112 HydrophobicContact CD2-CD2 3.99Å; L84-F112 HydrophobicContact CD2-CG 3.96Å; F112-E114 PolarHBondContact O-N 3.32Å; F112-M115 HydrophobicContact CE2-SD 4.3Å; F112-M115 WeakPolarHBondContact O-CB 3.17Å; F112-M115 PolarHBondContact O-N 3.44Å; F112-N124 HydrophobicContact CE2-CB 4.24Å; F112-N124 HydrophobicContact CZ-CB 4.14Å; F112-L125 HydrophobicContact CE2-CB 4.19Å; F112-L125 HydrophobicContact CE2-CD1 4.29Å; F112-L125 HydrophobicContact CZ-CB 4.12Å; F112-A128 HydrophobicContact CD2-CB 3.99Å; F112-A128 HydrophobicContact CE2-CB 4.07Å; F112-Q152 VanDerWaalsContact CD1-NE2 3.29Å; F112-Q152 VanDerWaalsContact CE1-NE2 3.35Å
113	A	85.9	Confident	82.7	Confident	61 Å²	61	75.2 Å²	75.2	50%	0.504	42%	0.418	S	S	.	.	G	3₁₀ helix	trans	-65.1	-21	178.6	0	0	0	0	0	114.2	I111	I111-A113 HydrophobicContact CD1-CB 4.09Å; I111-A113 HydrophobicContact CG1-CB 4.45Å; I111-A113 PolarHBondContact O-N 3.08Å
114	E	80.6	Confident	82.2	Confident	95 Å²	95	70.4 Å²	70.4	44%	0.444	39%	0.392	S	S	.	.	G	3₁₀ helix	trans	-88.4	-6.1	178.6	-73.9	176.3	163.1	0	0	113.2	L94 Q97 I110 I111 F112	L94-E114 VanDerWaalsContact CD2-OE1 3.29Å; L94-E114 WeakPolarHBondContact CD2-OE1 3.47Å; Q97-E114 PolarHBondContact NE2-OE2 3.32Å; I110-E114 HydrophobicContact CD1-CB 3.79Å; I110-E114 HydrophobicContact CG1-CB 3.76Å; I110-E114 WeakPolarHBondContact CG1-OE2 3.32Å; I111-E114 HydrophobicContact CD1-CG 3.97Å; I111-E114 HydrophobicContact CG1-CB 3.99Å; I111-E114 HydrophobicContact CG1-CG 3.51Å; I111-E114 PolarHBondContact O-N 2.96Å; I111-E114 VanDerWaalsContact O-N 3.12Å; F112-E114 PolarHBondContact O-N 3.32Å
115	M	71.6	Confident	81.8	Confident	29 Å²	29	67.6 Å²	67.6	14%	0.143	38%	0.38	C	S	.	.	S	Bend	trans	-67	134.7	-178.8	-176.6	165.9	-74.6	0	0	111	F112 C117 N124 A128	F112-M115 HydrophobicContact CE2-SD 4.3Å; F112-M115 WeakPolarHBondContact O-CB 3.17Å; F112-M115 PolarHBondContact O-N 3.44Å; M115-C117 PolarHBondContact O-N 3.47Å; M115-N124 HydrophobicContact SD-CB 3.96Å; M115-A128 HydrophobicContact CE-CB 3.33Å; M115-A128 HydrophobicContact SD-CB 3.94Å
116	P	66.1	Low	81.4	Confident	97 Å²	97	68.5 Å²	68.5	63%	0.63	38%	0.376	S	S	*	.	P	Polyproline II helix	trans	-51.5	129.7	-176.8	12.5	-27.7	0	0	0	113.2	N124	P116-N124 PolarHBondContact O-ND2 2.85Å
117	C	56.4	Low	81	Confident	127 Å²	127	70.4 Å²	70.4	86%	0.858	39%	0.386	S	S	*	.	S	Bend	trans	-82.8	125.6	178	-67.9	0	0	0	0	109.5	M115	M115-C117 PolarHBondContact O-N 3.47Å
118	G	55.4	Low	80.7	Confident	77 Å²	77	64 Å²	64	79%	0.794	36%	0.358	S	S	*	.	S	Bend	trans	174	-19.9	-179.7	0	0	0	0	0	114.8
119	R	61.9	Low	80.5	Confident	151 Å²	151	61.8 Å²	61.8	57%	0.57	34%	0.344	S	S	*	.	S	Bend	trans	-116.9	174.7	176.2	-56.7	178.3	176	-163.4	-3.8	111.8	Q123 N124 D127	R119-Q123 HydrophobicContact CB-CB 4.34Å; R119-N124 WeakPolarHBondContact CB-OD1 3.47Å; R119-D127 IonicContact NH1-OD2 2.74Å
120	Q	75.3	Confident	80.3	Confident	146 Å²	146	62.3 Å²	62.3	68%	0.682	35%	0.345	S	S	*	.			trans	-61	140.7	175	-65.7	-179.3	-9.2	0	0	110.1	L122 Q123 N124	Q120-L122 PolarHBondContact O-N 2.84Å; Q120-Q123 WeakPolarHBondContact O-CA 3.38Å; Q120-Q123 WeakPolarHBondContact O-CB 3.25Å; Q120-Q123 PolarHBondContact O-N 2.86Å; Q120-N124 PolarHBondContact O-N 3.14Å; Q120-N124 VanDerWaalsContact O-N 3.14Å
121	H	76	Confident	80.1	Confident	132 Å²	132	61.2 Å²	61.2	61%	0.611	34%	0.342	S	S	*	.	H	α-helix	trans	-54.6	-33.2	-175.3	-74.8	50.1	0	0	0	113.4	L125 W148	H121-L125 PolarHBondContact O-N 3.46Å; H121-L125 VanDerWaalsContact O-N 3.09Å; H121-W148 HydrophobicContact CB-CH2 3.75Å; H121-W148 HydrophobicContact CB-CZ2 3.81Å
122	L	79.1	Confident	80.1	Confident	89 Å²	89	61.1 Å²	61.1	47%	0.466	34%	0.342	S	S	.	.	H	α-helix	trans	-65.8	-38	175.7	-63.3	177.4	0	0	0	112.7	Q120 L125 D126 W148 F151	Q120-L122 PolarHBondContact O-N 2.84Å; L122-L125 PolarHBondContact O-N 2.84Å; L122-D126 PolarHBondContact O-N 2.78Å; L122-D126 VanDerWaalsContact O-N 3.08Å; L122-W148 HydrophobicContact CD2-CH2 3.8Å; L122-W148 HydrophobicContact CD2-CZ3 3.8Å; L122-W148 HydrophobicContact CG-CH2 4.49Å; L122-F151 HydrophobicContact CD2-CD1 3.96Å; L122-F151 HydrophobicContact CD2-CE1 3.08Å; L122-F151 HydrophobicContact CD2-CE2 4.2Å; L122-F151 HydrophobicContact CD2-CZ 3.25Å
123	Q	82.6	Confident	80.4	Confident	86 Å²	86	59.8 Å²	59.8	40%	0.402	34%	0.336	S	S	.	.	H	α-helix	trans	-71.2	-42.7	178.8	-169.8	165.6	25.6	0	0	110.4	R119 Q120 L125 D126 D127	R119-Q123 HydrophobicContact CB-CB 4.34Å; Q120-Q123 WeakPolarHBondContact O-CA 3.38Å; Q120-Q123 WeakPolarHBondContact O-CB 3.25Å; Q120-Q123 PolarHBondContact O-N 2.86Å; Q123-L125 VanDerWaalsContact C-N 3.26Å; Q123-L125 PolarHBondContact O-N 3.28Å; Q123-D126 PolarHBondContact O-N 3.22Å; Q123-D126 VanDerWaalsContact O-N 3.15Å; Q123-D127 WeakPolarHBondContact O-CB 3.4Å; Q123-D127 VanDerWaalsContact O-CG 3.24Å; Q123-D127 PolarHBondContact O-N 3.41Å
124	N	84.8	Confident	80.9	Confident	19 Å²	19	57.2 Å²	57.2	10%	0.102	31%	0.313	C	S	.	.	H	α-helix	trans	-57.3	-41.4	173.1	-73.5	16	0	0	0	111.5	F112 M115 P116 R119 Q120 D127 A128	F112-N124 HydrophobicContact CE2-CB 4.24Å; F112-N124 HydrophobicContact CZ-CB 4.14Å; M115-N124 HydrophobicContact SD-CB 3.96Å; P116-N124 PolarHBondContact O-ND2 2.85Å; R119-N124 WeakPolarHBondContact CB-OD1 3.47Å; Q120-N124 PolarHBondContact O-N 3.14Å; Q120-N124 VanDerWaalsContact O-N 3.14Å; N124-D127 PolarHBondContact O-N 2.76Å; N124-A128 VanDerWaalsContact O-CB 3.25Å; N124-A128 WeakPolarHBondContact O-CB 3.45Å; N124-A128 PolarHBondContact O-N 2.84Å
125	L	87.3	Confident	81.6	Confident	0 Å²	0	52.7 Å²	52.7	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-63.2	-46.4	175.9	179	66.9	0	0	0	112.3	L84 F112 H121 L122 Q123 D127 A128 V129 F151 Q152 T155	L84-L125 HydrophobicContact CD1-CD1 3.92Å; L84-L125 HydrophobicContact CD2-CD1 4.11Å; F112-L125 HydrophobicContact CE2-CB 4.19Å; F112-L125 HydrophobicContact CE2-CD1 4.29Å; F112-L125 HydrophobicContact CZ-CB 4.12Å; H121-L125 PolarHBondContact O-N 3.46Å; H121-L125 VanDerWaalsContact O-N 3.09Å; L122-L125 PolarHBondContact O-N 2.84Å; Q123-L125 VanDerWaalsContact C-N 3.26Å; Q123-L125 PolarHBondContact O-N 3.28Å; L125-D127 VanDerWaalsContact C-N 3.34Å; L125-A128 WeakPolarHBondContact O-CB 3.16Å; L125-A128 PolarHBondContact O-N 3.44Å; L125-V129 HydrophobicContact CD1-CG2 4.1Å; L125-V129 HydrophobicContact CG-CG2 4.47Å; L125-V129 VanDerWaalsContact O-CG2 3.32Å; L125-V129 WeakPolarHBondContact O-CG2 3.49Å; L125-V129 PolarHBondContact O-N 3.12Å; L125-F151 HydrophobicContact CD2-CD1 4.06Å; L125-F151 HydrophobicContact CD2-CE1 3.7Å; L125-Q152 HydrophobicContact CD1-CB 4.3Å; L125-Q152 HydrophobicContact CD1-CG 3.98Å; L125-Q152 HydrophobicContact CD2-CB 4.34Å; L125-Q152 HydrophobicContact CD2-CG 4.01Å; L125-T155 HydrophobicContact CD2-CG2 3.89Å
126	D	87.1	Confident	82.8	Confident	58 Å²	58	51.3 Å²	51.3	31%	0.31	29%	0.285	S	S	.	.	H	α-helix	trans	-63.8	-42.3	178.4	-171.5	64.6	0	0	0	111.2	L122 Q123 A128 V129 N130	L122-D126 PolarHBondContact O-N 2.78Å; L122-D126 VanDerWaalsContact O-N 3.08Å; Q123-D126 PolarHBondContact O-N 3.22Å; Q123-D126 VanDerWaalsContact O-N 3.15Å; D126-A128 VanDerWaalsContact C-N 3.34Å; D126-A128 PolarHBondContact O-N 3.47Å; D126-V129 PolarHBondContact O-N 2.98Å; D126-N130 WeakPolarHBondContact O-CB 3.31Å; D126-N130 PolarHBondContact O-N 3.47Å; D126-N130 PolarHBondContact O-ND2 3.32Å; D126-N130 VanDerWaalsContact O-ND2 3.14Å; D126-N130 PolarHBondContact OD1-ND2 3.49Å; D126-N130 PolarHBondContact OD2-ND2 3.39Å
127	D	88.1	Confident	84.2	Confident	55 Å²	55	46.7 Å²	46.7	29%	0.294	26%	0.255	S	S	.	.	H	α-helix	trans	-61.4	-41.6	175.7	-69.7	-18.4	0	0	0	110.7	R119 Q123 N124 L125 G131	R119-D127 IonicContact NH1-OD2 2.74Å; Q123-D127 WeakPolarHBondContact O-CB 3.4Å; Q123-D127 VanDerWaalsContact O-CG 3.24Å; Q123-D127 PolarHBondContact O-N 3.41Å; N124-D127 PolarHBondContact O-N 2.76Å; L125-D127 VanDerWaalsContact C-N 3.34Å; D127-G131 VanDerWaalsContact O-CA 3.3Å; D127-G131 WeakPolarHBondContact O-CA 3.38Å; D127-G131 PolarHBondContact O-N 3.3Å
128	A	89.6	Confident	86	Confident	2 Å²	2	40.7 Å²	40.7	2%	0.017	21%	0.214	C	C	.	.	H	α-helix	trans	-62.8	-50.4	175.4	0	0	0	0	0	113.5	V82 F112 M115 N124 L125 D126 S132	V82-A128 HydrophobicContact CG1-CB 4.37Å; V82-A128 HydrophobicContact CG2-CB 4.2Å; F112-A128 HydrophobicContact CD2-CB 3.99Å; F112-A128 HydrophobicContact CE2-CB 4.07Å; M115-A128 HydrophobicContact CE-CB 3.33Å; M115-A128 HydrophobicContact SD-CB 3.94Å; N124-A128 VanDerWaalsContact O-CB 3.25Å; N124-A128 WeakPolarHBondContact O-CB 3.45Å; N124-A128 PolarHBondContact O-N 2.84Å; L125-A128 WeakPolarHBondContact O-CB 3.16Å; L125-A128 PolarHBondContact O-N 3.44Å; D126-A128 VanDerWaalsContact C-N 3.34Å; D126-A128 PolarHBondContact O-N 3.47Å; A128-S132 WeakPolarHBondContact O-CB 3.46Å; A128-S132 PolarHBondContact O-N 3.32Å; A128-S132 PolarHBondContact O-OG 2.93Å
129	V	90.7	Very high	87.8	Confident	1 Å²	1	37 Å²	37	1%	0.006	18%	0.177	C	C	.	.	H	α-helix	trans	-68.4	-38.6	-177.9	172.8	0	0	0	0	110.4	L125 D126 T135 S156 N159 K166	L125-V129 HydrophobicContact CD1-CG2 4.1Å; L125-V129 HydrophobicContact CG-CG2 4.47Å; L125-V129 VanDerWaalsContact O-CG2 3.32Å; L125-V129 WeakPolarHBondContact O-CG2 3.49Å; L125-V129 PolarHBondContact O-N 3.12Å; D126-V129 PolarHBondContact O-N 2.98Å; V129-T135 HydrophobicContact CG2-CG2 4.24Å; V129-S156 WeakPolarHBondContact CG2-OG 3.39Å; V129-N159 HydrophobicContact CG1-CB 3.94Å; V129-K166 PolarHBondContact O-NZ 2.87Å
130	N	89.5	Confident	89.3	Confident	20 Å²	20	29.9 Å²	29.9	11%	0.107	15%	0.15	C	C	.	.	H	α-helix	trans	-79.3	-35.1	-179.7	-67.1	-35.4	0	0	0	112.5	D126 S132 N159 R163 K166	D126-N130 WeakPolarHBondContact O-CB 3.31Å; D126-N130 PolarHBondContact O-N 3.47Å; D126-N130 PolarHBondContact O-ND2 3.32Å; D126-N130 VanDerWaalsContact O-ND2 3.14Å; D126-N130 PolarHBondContact OD1-ND2 3.49Å; D126-N130 PolarHBondContact OD2-ND2 3.39Å; N130-S132 VanDerWaalsContact C-N 3.29Å; N130-S132 PolarHBondContact O-N 2.93Å; N130-N159 PolarHBondContact OD1-ND2 3.26Å; N130-R163 VanDerWaalsContact CG-NH1 3.29Å; N130-R163 PolarHBondContact ND2-NH1 2.93Å; N130-R163 PolarHBondContact ND2-NH2 3.38Å; N130-R163 VanDerWaalsContact OD1-CZ 3.24Å; N130-R163 PolarHBondContact OD1-NH1 3.41Å; N130-K166 PolarHBondContact O-NZ 3.39Å
131	G	91.1	Very high	89.9	Confident	11 Å²	11	25.5 Å²	25.5	11%	0.113	13%	0.13	C	C	.	.	S	Bend	trans	-80.6	2.3	179.5	0	0	0	0	0	115.5	F78 L79 D127	F78-G131 WeakPolarHBondContact CD2-O 3.47Å; L79-G131 PolarHBondContact N-O 3.13Å; D127-G131 VanDerWaalsContact O-CA 3.3Å; D127-G131 WeakPolarHBondContact O-CA 3.38Å; D127-G131 PolarHBondContact O-N 3.3Å
132	S	93.9	Very high	90.4	Very high	0 Å²	0	21.2 Å²	21.2	0%	0	11%	0.111	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-122.5	152.4	176.9	58.4	0	0	0	0	112.6	L79 V82 A128 N130 W134 K166	L79-S132 CarbonylContact O-C 3.52Å; L79-S132 VanDerWaalsContact O-CA 3.28Å; L79-S132 WeakPolarHBondContact O-CA 3.29Å; V82-S132 WeakPolarHBondContact CG1-OG 3.13Å; A128-S132 WeakPolarHBondContact O-CB 3.46Å; A128-S132 PolarHBondContact O-N 3.32Å; A128-S132 PolarHBondContact O-OG 2.93Å; N130-S132 VanDerWaalsContact C-N 3.29Å; N130-S132 PolarHBondContact O-N 2.93Å; S132-W134 PolarHBondContact OG-O 2.99Å; S132-K166 PolarHBondContact O-NZ 3.37Å
133	A	94.9	Very high	90.4	Very high	0 Å²	0	17 Å²	17	0%	0	9%	0.089	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-77	-31.4	174.7	0	0	0	0	0	113.3	F78 L79 K80 S169 Y215 Q218	F78-A133 HydrophobicContact CE1-CB 3.93Å; F78-A133 HydrophobicContact CZ-CB 4.04Å; L79-A133 PolarHBondContact O-N 3.07Å; K80-A133 WeakPolarHBondContact O-CA 3.11Å; K80-A133 WeakPolarHBondContact O-CB 3.46Å; K80-A133 PolarHBondContact O-N 3.11Å; A133-S169 VanDerWaalsContact O-CB 3.29Å; A133-S169 WeakPolarHBondContact O-CB 3.17Å; A133-Y215 HydrophobicContact CB-CD2 3.76Å; A133-Q218 VanDerWaalsContact CA-OE1 3.3Å; A133-Q218 HydrophobicContact CB-CB 4.4Å; A133-Q218 PolarHBondContact O-NE2 3.16Å; A133-Q218 PolarHBondContact O-OE1 3.27Å; A133-Q218 VanDerWaalsContact O-OE1 3.11Å
134	W	96.3	Very high	90.1	Very high	6 Å²	6	14.8 Å²	14.8	2%	0.023	8%	0.08	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-132.8	140.7	178.4	-60.1	-84.5	0	0	0	111.4	K80 F81 V82 S132 S169 I171 I209 F210 Q211 V214 Y215	K80-W134 HydrophobicContact CB-CE3 4.42Å; K80-W134 HydrophobicContact CB-CZ3 4.23Å; K80-W134 PolarHBondContact O-N 2.91Å; F81-W134 CarbonylContact C-O 3.6Å; F81-W134 WeakPolarHBondContact CA-O 3.31Å; F81-W134 HydrophobicContact CB-CB 4.29Å; V82-W134 PolarHBondContact N-O 3.32Å; S132-W134 PolarHBondContact OG-O 2.99Å; W134-S169 CarbonylContact C-O 3.39Å; W134-S169 VanDerWaalsContact CA-O 3.29Å; W134-S169 WeakPolarHBondContact CA-O 3.35Å; W134-I171 HydrophobicContact CB-CG1 4.4Å; W134-I209 WeakPolarHBondContact CZ2-O 3.48Å; W134-I209 PolarHBondContact NE1-O 3.28Å; W134-F210 HydrophobicContact CB-CE1 4.04Å; W134-F210 AromaticContact CD2-CD1 3.66Å; W134-F210 HydrophobicContact CD2-CD1 3.66Å; W134-F210 HydrophobicContact CD2-CE1 4.1Å; W134-F210 AromaticContact CE3-CD1 3.55Å; W134-F210 HydrophobicContact CE3-CD1 3.55Å; W134-F210 HydrophobicContact CE3-CE1 4.18Å; W134-F210 HydrophobicContact CG-CD1 4.06Å; W134-F210 HydrophobicContact CG-CE1 4.02Å; W134-F210 HydrophobicContact CH2-CB 4.35Å; W134-F210 HydrophobicContact CH2-CD1 4.49Å; W134-F210 HydrophobicContact CZ3-CB 4.44Å; W134-F210 HydrophobicContact CZ3-CD1 4.02Å; W134-Q211 WeakPolarHBondContact CH2-O 3.22Å; W134-V214 HydrophobicContact CZ2-CB 3.91Å; W134-V214 HydrophobicContact CZ2-CG1 3.82Å; W134-Y215 HydrophobicContact CZ3-CD2 4.36Å
135	T	95.9	Very high	89.8	Confident	1 Å²	1	22.2 Å²	22.2	1%	0.006	11%	0.106	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-109.4	111.4	172.9	-55.2	0	0	0	0	108.3	V82 L84 V129 L137 S169 V170 I171	V82-T135 HydrophobicContact CG1-CG2 4.1Å; L84-T135 HydrophobicContact CD1-CG2 3.66Å; L84-T135 HydrophobicContact CG-CG2 3.84Å; V129-T135 HydrophobicContact CG2-CG2 4.24Å; T135-L137 HydrophobicContact CG2-CD2 4.25Å; T135-S169 PolarHBondContact N-O 3.31Å; T135-V170 CarbonylContact O-C 3.58Å; T135-V170 WeakPolarHBondContact O-CA 3.18Å; T135-I171 PolarHBondContact O-N 3.46Å
136	I	96.4	Very high	89.4	Confident	0 Å²	0	24.6 Å²	24.6	0%	0	12%	0.119	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-90.6	123.1	179.8	-58.8	176.8	0	0	0	108.2	F81 V82 I83 L84 L100 I171 M173 F210	F81-I136 HydrophobicContact CB-CD1 3.98Å; F81-I136 HydrophobicContact CB-CG1 4.31Å; F81-I136 HydrophobicContact CD1-CD1 4.5Å; F81-I136 HydrophobicContact CD2-CD1 3.84Å; F81-I136 HydrophobicContact CE2-CD1 4.48Å; F81-I136 HydrophobicContact CG-CD1 3.86Å; V82-I136 PolarHBondContact O-N 3.27Å; I83-I136 WeakPolarHBondContact CA-O 3.41Å; I83-I136 HydrophobicContact CG1-CB 4.18Å; I83-I136 HydrophobicContact CG1-CD1 4.3Å; L84-I136 PolarHBondContact N-O 3.38Å; L100-I136 HydrophobicContact CD1-CD1 3.47Å; L100-I136 VanDerWaalsContact CD1-CD1 3.47Å; I136-I171 CarbonylContact C-O 3.57Å; I136-I171 VanDerWaalsContact CA-O 3.3Å; I136-I171 WeakPolarHBondContact CA-O 3.37Å; I136-I171 HydrophobicContact CG1-CB 4.47Å; I136-M173 HydrophobicContact CG2-CB 3.51Å; I136-M173 HydrophobicContact CG2-CG 4.25Å; I136-F210 HydrophobicContact CD1-CE1 4.17Å; I136-F210 HydrophobicContact CD1-CZ 3.82Å; I136-F210 HydrophobicContact CG1-CZ 4.42Å
137	L	95	Very high	88.9	Confident	0 Å²	0	27.6 Å²	27.6	0%	0	14%	0.139	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-98.1	111.3	173.7	-55.4	179.7	0	0	0	108.6	L84 T135 L139 F143 F153 V170 I171 M173 L189	L84-L137 HydrophobicContact CB-CD2 4.02Å; L84-L137 HydrophobicContact CD1-CD2 3.7Å; L84-L137 HydrophobicContact CG-CD2 4.14Å; T135-L137 HydrophobicContact CG2-CD2 4.25Å; L137-L139 HydrophobicContact CB-CD2 4.43Å; L137-L139 PolarHBondContact O-N 2.85Å; L137-F143 HydrophobicContact CB-CZ 4.39Å; L137-F143 HydrophobicContact CD2-CZ 4.27Å; L137-F153 HydrophobicContact CD1-CD2 3.78Å; L137-V170 HydrophobicContact CD1-CG1 3.61Å; L137-V170 HydrophobicContact CG-CG1 3.95Å; L137-I171 PolarHBondContact N-O 2.94Å; L137-M173 PolarHBondContact O-N 3.43Å; L137-L189 HydrophobicContact CD1-CD1 4.18Å; L137-L189 HydrophobicContact CD1-CD2 4.04Å
138	L	95.3	Very high	88.3	Confident	0 Å²	0	28.5 Å²	28.5	0%	0	14%	0.139	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-76.1	105.4	-179.3	-167.5	67.7	0	0	0	109.9	I83 L84 H85 D89 E92 A93 V96 T140 F143 M173 P175	I83-L138 HydrophobicContact CG2-CB 4.15Å; L84-L138 WeakPolarHBondContact O-CB 3.44Å; L84-L138 PolarHBondContact O-N 3.21Å; H85-L138 HydrophobicContact CB-CB 4.1Å; H85-L138 HydrophobicContact CB-CD2 3.86Å; D89-L138 HydrophobicContact CB-CD2 4.28Å; E92-L138 HydrophobicContact CB-CD2 4.37Å; E92-L138 HydrophobicContact CG-CD2 4.27Å; A93-L138 HydrophobicContact CB-CD2 4.02Å; V96-L138 HydrophobicContact CG2-CD1 4.2Å; L138-T140 HydrophobicContact CD2-CG2 4.12Å; L138-T140 HydrophobicContact CG-CG2 3.99Å; L138-T140 PolarHBondContact O-N 2.7Å; L138-T140 VanDerWaalsContact O-N 3.1Å; L138-F143 VanDerWaalsContact O-CB 3.29Å; L138-F143 WeakPolarHBondContact O-CB 3.47Å; L138-F143 WeakPolarHBondContact O-CD2 3.27Å; L138-F143 VanDerWaalsContact O-CG 3.24Å; L138-F143 WeakPolarHBondContact O-CG 3.34Å; L138-M173 HydrophobicContact CD1-SD 3.45Å; L138-M173 WeakPolarHBondContact CD1-SD 3.39Å; L138-P175 HydrophobicContact CD1-CB 4.09Å; L138-P175 HydrophobicContact CD1-CG 3.92Å; L138-P175 HydrophobicContact CG-CG 4.36Å
139	L	93.6	Very high	87.9	Confident	0 Å²	0	28.4 Å²	28.4	0%	0	14%	0.138	C	C	.	.			trans	-85.2	81.5	-175.6	-58.5	-173.4	0	0	0	111.1	L137 F143 P172 M173 R174 L180 T185 L189	L137-L139 HydrophobicContact CB-CD2 4.43Å; L137-L139 PolarHBondContact O-N 2.85Å; L139-F143 HydrophobicContact CD2-CD1 4.46Å; L139-P172 HydrophobicContact CD1-CB 3.69Å; L139-P172 HydrophobicContact CG-CB 4.19Å; L139-M173 WeakPolarHBondContact CB-O 3.31Å; L139-M173 PolarHBondContact N-O 3.22Å; L139-R174 HydrophobicContact CB-CG 4.22Å; L139-R174 HydrophobicContact CD1-CG 4.12Å; L139-L180 HydrophobicContact CB-CB 4.03Å; L139-L180 HydrophobicContact CB-CD2 4.45Å; L139-L180 VanDerWaalsContact O-CB 3.31Å; L139-L180 WeakPolarHBondContact O-CB 3.38Å; L139-L180 PolarHBondContact O-N 3.4Å; L139-T185 HydrophobicContact CD1-CG2 4.29Å; L139-L189 HydrophobicContact CD2-CD1 3.81Å
140	T	92.3	Very high	87.4	Confident	1 Å²	1	30.5 Å²	30.5	1%	0.006	15%	0.149	C	C	.	.	B	Isolated β-bridge	trans	-101.2	171	169.7	64.7	0	0	0	0	111.2	D89 L138 N142 F143 P175 N178	D89-T140 HydrophobicContact CB-CG2 4.15Å; D89-T140 VanDerWaalsContact OD2-CB 3.27Å; D89-T140 WeakPolarHBondContact OD2-CB 3.41Å; D89-T140 WeakPolarHBondContact OD2-CG2 3.24Å; D89-T140 PolarHBondContact OD2-OG1 2.98Å; L138-T140 HydrophobicContact CD2-CG2 4.12Å; L138-T140 HydrophobicContact CG-CG2 3.99Å; L138-T140 PolarHBondContact O-N 2.7Å; L138-T140 VanDerWaalsContact O-N 3.1Å; T140-N142 PolarHBondContact O-N 3.24Å; T140-N142 PolarHBondContact OG1-N 3.22Å; T140-F143 PolarHBondContact O-N 3.19Å; T140-F143 PolarHBondContact OG1-N 2.79Å; T140-F143 VanDerWaalsContact OG1-N 3.09Å; T140-P175 HydrophobicContact CG2-CG 3.99Å; T140-N178 WeakPolarHBondContact CA-O 3.48Å
141	E	87.9	Confident	87.1	Confident	55 Å²	55	33.5 Å²	33.5	26%	0.257	16%	0.161	S	C	.	.	T	Hydrogen-bonded Turn	trans	-63.3	-23.9	170.2	-70.1	-149.7	158.5	0	0	114.1	R145 N178 R184	E141-R145 WeakPolarHBondContact O-CD 3.38Å; E141-R145 WeakPolarHBondContact O-CG 3.18Å; E141-R145 PolarHBondContact O-NE 3.48Å; E141-R145 IonicContact OE2-NH2 3.88Å; E141-N178 WeakPolarHBondContact CG-OD1 3.45Å; E141-N178 PolarHBondContact N-O 2.73Å; E141-R184 IonicContact OE1-NH1 3.69Å; E141-R184 PolarHBondContact OE1-NH1 2.94Å; E141-R184 IonicContact OE2-NH1 3.29Å
142	N	86.4	Confident	86.7	Confident	41 Å²	41	33.1 Å²	33.1	22%	0.219	16%	0.157	C	C	.	.	T	Hydrogen-bonded Turn	trans	-84.3	-31.4	-178.6	-59.1	-39.3	0	0	0	111.7	A86 D88 D89 T140 L144 R145 D146	A86-N142 HydrophobicContact CB-CB 3.94Å; D88-N142 HydrophobicContact CB-CB 4.5Å; D89-N142 PolarHBondContact OD1-ND2 2.94Å; D89-N142 WeakPolarHBondContact OD2-CB 3.47Å; T140-N142 PolarHBondContact O-N 3.24Å; T140-N142 PolarHBondContact OG1-N 3.22Å; N142-L144 VanDerWaalsContact C-N 3.31Å; N142-L144 PolarHBondContact O-N 2.83Å; N142-R145 WeakPolarHBondContact O-CB 3.46Å; N142-R145 PolarHBondContact O-N 3.03Å; N142-D146 PolarHBondContact O-N 2.94Å
143	F	79.9	Confident	86.2	Confident	0 Å²	0	33.2 Å²	33.2	0%	0	16%	0.157	C	C	.	.	T	Hydrogen-bonded Turn	trans	-55.7	-39.1	-177.9	-171.6	-96.8	0	0	0	114	L84 L137 L138 L139 T140 C149 F153	L84-F143 HydrophobicContact CB-CE2 4.41Å; L137-F143 HydrophobicContact CB-CZ 4.39Å; L137-F143 HydrophobicContact CD2-CZ 4.27Å; L138-F143 VanDerWaalsContact O-CB 3.29Å; L138-F143 WeakPolarHBondContact O-CB 3.47Å; L138-F143 WeakPolarHBondContact O-CD2 3.27Å; L138-F143 VanDerWaalsContact O-CG 3.24Å; L138-F143 WeakPolarHBondContact O-CG 3.34Å; L139-F143 HydrophobicContact CD2-CD1 4.46Å; T140-F143 PolarHBondContact O-N 3.19Å; T140-F143 PolarHBondContact OG1-N 2.79Å; T140-F143 VanDerWaalsContact OG1-N 3.09Å; F143-C149 HydrophobicContact CD1-CB 4.49Å; F143-C149 HydrophobicContact CD2-CB 3.92Å; F143-C149 HydrophobicContact CE1-CB 4.45Å; F143-C149 HydrophobicContact CE2-CB 3.88Å; F143-C149 HydrophobicContact CG-CB 4.23Å; F143-C149 HydrophobicContact CZ-CB 4.15Å; F143-C149 WeakPolarHBondContact O-CB 3.43Å; F143-F153 HydrophobicContact CE1-CB 4.29Å; F143-F153 HydrophobicContact CZ-CB 4.45Å
144	L	75.3	Confident	85.8	Confident	40 Å²	40	39.6 Å²	39.6	21%	0.209	18%	0.182	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.1	-13.7	179.2	-65.4	-175.4	0	0	0	114.4	N142 N150 L180 R184 P186	N142-L144 VanDerWaalsContact C-N 3.31Å; N142-L144 PolarHBondContact O-N 2.83Å; L144-N150 PolarHBondContact O-ND2 2.89Å; L144-L180 HydrophobicContact CD1-CD1 3.95Å; L144-L180 HydrophobicContact CD1-CD2 3.37Å; L144-L180 HydrophobicContact CD1-CG 4.3Å; L144-L180 HydrophobicContact CG-CD1 4.49Å; L144-L180 HydrophobicContact CG-CD2 3.92Å; L144-R184 VanDerWaalsContact CD1-O 3.25Å; L144-R184 WeakPolarHBondContact CD1-O 3.41Å; L144-P186 HydrophobicContact CD1-CG 4.12Å; L144-P186 HydrophobicContact CD2-CG 3.78Å
145	R	79.1	Confident	85.4	Confident	176 Å²	176	41.1 Å²	41.1	66%	0.664	19%	0.192	S	C	*	.	T	Hydrogen-bonded Turn	trans	-78.3	-29.5	-179.3	-67.5	175.6	-176.9	-99.6	5.8	111.4	E141 N142	E141-R145 WeakPolarHBondContact O-CD 3.38Å; E141-R145 WeakPolarHBondContact O-CG 3.18Å; E141-R145 PolarHBondContact O-NE 3.48Å; E141-R145 IonicContact OE2-NH2 3.88Å; N142-R145 WeakPolarHBondContact O-CB 3.46Å; N142-R145 PolarHBondContact O-N 3.03Å
146	D	78.5	Confident	84.9	Confident	50 Å²	50	41.1 Å²	41.1	27%	0.267	19%	0.192	S	C	.	.			trans	-82.3	125.7	178.6	179.6	14.8	0	0	0	111.5	N142 W148 C149 N150	N142-D146 PolarHBondContact O-N 2.94Å; D146-W148 PolarHBondContact O-N 3.29Å; D146-W148 WeakPolarHBondContact OD1-CB 3.38Å; D146-W148 PolarHBondContact OD1-N 2.82Å; D146-W148 WeakPolarHBondContact OD2-CB 3.29Å; D146-C149 HydrophobicContact CB-CB 4Å; D146-C149 PolarHBondContact O-N 3.13Å; D146-C149 PolarHBondContact OD2-N 3.28Å; D146-C149 PolarHBondContact OD2-SG 3.27Å; D146-N150 PolarHBondContact O-N 2.81Å; D146-N150 VanDerWaalsContact O-N 3.14Å; D146-N150 PolarHBondContact O-ND2 2.95Å
147	T	76.3	Confident	84.5	Confident	120 Å²	120	41.9 Å²	41.9	74%	0.736	20%	0.196	S	C	*	.	H	α-helix	trans	-61.6	-31.7	173.5	39.8	0	0	0	0	112.6	N150 F151	T147-N150 PolarHBondContact O-N 3.46Å; T147-F151 PolarHBondContact O-N 3.02Å; T147-F151 VanDerWaalsContact O-N 3.15Å
148	W	77.3	Confident	84.1	Confident	74 Å²	74	46 Å²	46	28%	0.28	22%	0.217	S	C	.	.	H	α-helix	trans	-70.8	-42.6	177.5	176.7	-114.7	0	0	0	111.4	H121 L122 D146 N150 F151 Q152	H121-W148 HydrophobicContact CB-CH2 3.75Å; H121-W148 HydrophobicContact CB-CZ2 3.81Å; L122-W148 HydrophobicContact CD2-CH2 3.8Å; L122-W148 HydrophobicContact CD2-CZ3 3.8Å; L122-W148 HydrophobicContact CG-CH2 4.49Å; D146-W148 PolarHBondContact O-N 3.29Å; D146-W148 WeakPolarHBondContact OD1-CB 3.38Å; D146-W148 PolarHBondContact OD1-N 2.82Å; D146-W148 WeakPolarHBondContact OD2-CB 3.29Å; W148-N150 VanDerWaalsContact C-N 3.3Å; W148-N150 PolarHBondContact O-N 3.11Å; W148-F151 HydrophobicContact CE3-CB 4.39Å; W148-F151 AromaticContact CE3-CD1 3.98Å; W148-F151 HydrophobicContact CE3-CD1 3.98Å; W148-F151 HydrophobicContact CE3-CG 4.44Å; W148-F151 HydrophobicContact CH2-CD1 4.03Å; W148-F151 HydrophobicContact CH2-CE1 4.24Å; W148-F151 AromaticContact CZ3-CD1 3.54Å; W148-F151 HydrophobicContact CZ3-CD1 3.54Å; W148-F151 HydrophobicContact CZ3-CE1 4.03Å; W148-F151 HydrophobicContact CZ3-CG 4.29Å; W148-F151 WeakPolarHBondContact O-CA 3.31Å; W148-F151 WeakPolarHBondContact O-CB 3.5Å; W148-F151 PolarHBondContact O-N 3.36Å; W148-Q152 HydrophobicContact CD2-CG 4.44Å; W148-Q152 HydrophobicContact CZ2-CG 4.35Å; W148-Q152 VanDerWaalsContact NE1-NE2 3.14Å; W148-Q152 WeakPolarHBondContact O-CG 3.45Å; W148-Q152 PolarHBondContact O-N 2.59Å
149	C	79.8	Confident	83.7	Confident	0 Å²	0	46.7 Å²	46.7	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-59.7	-37	171.6	-69.9	0	0	0	0	113	A86 F143 D146 F151 Q152 F153	A86-C149 VanDerWaalsContact CA-SG 3.59Å; F143-C149 HydrophobicContact CD1-CB 4.49Å; F143-C149 HydrophobicContact CD2-CB 3.92Å; F143-C149 HydrophobicContact CE1-CB 4.45Å; F143-C149 HydrophobicContact CE2-CB 3.88Å; F143-C149 HydrophobicContact CG-CB 4.23Å; F143-C149 HydrophobicContact CZ-CB 4.15Å; F143-C149 WeakPolarHBondContact O-CB 3.43Å; D146-C149 HydrophobicContact CB-CB 4Å; D146-C149 PolarHBondContact O-N 3.13Å; D146-C149 PolarHBondContact OD2-N 3.28Å; D146-C149 PolarHBondContact OD2-SG 3.27Å; C149-F151 VanDerWaalsContact C-N 3.35Å; C149-F151 PolarHBondContact O-N 2.99Å; C149-Q152 PolarHBondContact O-N 2.91Å; C149-F153 VanDerWaalsContact O-CB 3.26Å; C149-F153 WeakPolarHBondContact O-CB 3.25Å; C149-F153 PolarHBondContact O-N 2.85Å
150	N	81.6	Confident	83.3	Confident	46 Å²	46	47 Å²	47	25%	0.246	22%	0.222	C	C	.	.	H	α-helix	trans	-62	-41.9	172.2	-79.8	-70.6	0	0	0	112	L144 D146 T147 W148 F153 Y154	L144-N150 PolarHBondContact O-ND2 2.89Å; D146-N150 PolarHBondContact O-N 2.81Å; D146-N150 VanDerWaalsContact O-N 3.14Å; D146-N150 PolarHBondContact O-ND2 2.95Å; T147-N150 PolarHBondContact O-N 3.46Å; W148-N150 VanDerWaalsContact C-N 3.3Å; W148-N150 PolarHBondContact O-N 3.11Å; N150-F153 WeakPolarHBondContact O-CB 3.45Å; N150-F153 PolarHBondContact O-N 3.11Å; N150-Y154 WeakPolarHBondContact O-CD2 3.47Å; N150-Y154 PolarHBondContact O-N 3.45Å
151	F	83.3	Confident	83	Confident	82 Å²	82	51.2 Å²	51.2	36%	0.36	25%	0.248	S	C	.	.	H	α-helix	trans	-64.2	-45.5	175.3	175.1	-92.2	0	0	0	112.1	L122 L125 T147 W148 C149 F153 Y154 T155	L122-F151 HydrophobicContact CD2-CD1 3.96Å; L122-F151 HydrophobicContact CD2-CE1 3.08Å; L122-F151 HydrophobicContact CD2-CE2 4.2Å; L122-F151 HydrophobicContact CD2-CZ 3.25Å; L125-F151 HydrophobicContact CD2-CD1 4.06Å; L125-F151 HydrophobicContact CD2-CE1 3.7Å; T147-F151 PolarHBondContact O-N 3.02Å; T147-F151 VanDerWaalsContact O-N 3.15Å; W148-F151 HydrophobicContact CE3-CB 4.39Å; W148-F151 AromaticContact CE3-CD1 3.98Å; W148-F151 HydrophobicContact CE3-CD1 3.98Å; W148-F151 HydrophobicContact CE3-CG 4.44Å; W148-F151 HydrophobicContact CH2-CD1 4.03Å; W148-F151 HydrophobicContact CH2-CE1 4.24Å; W148-F151 AromaticContact CZ3-CD1 3.54Å; W148-F151 HydrophobicContact CZ3-CD1 3.54Å; W148-F151 HydrophobicContact CZ3-CE1 4.03Å; W148-F151 HydrophobicContact CZ3-CG 4.29Å; W148-F151 WeakPolarHBondContact O-CA 3.31Å; W148-F151 WeakPolarHBondContact O-CB 3.5Å; W148-F151 PolarHBondContact O-N 3.36Å; C149-F151 VanDerWaalsContact C-N 3.35Å; C149-F151 PolarHBondContact O-N 2.99Å; F151-F153 VanDerWaalsContact C-N 3.29Å; F151-F153 PolarHBondContact O-N 2.95Å; F151-Y154 PolarHBondContact O-N 2.8Å; F151-T155 WeakPolarHBondContact CE1-OG1 3.4Å; F151-T155 WeakPolarHBondContact CZ-OG1 3.38Å; F151-T155 WeakPolarHBondContact O-CB 3.41Å; F151-T155 PolarHBondContact O-N 3.43Å; F151-T155 PolarHBondContact O-OG1 2.97Å
152	Q	82.4	Confident	82.9	Confident	3 Å²	3	54.7 Å²	54.7	1%	0.014	27%	0.268	C	S	.	.	H	α-helix	trans	-57.1	-44.5	175.3	-74.1	179.4	-34	0	0	111.6	L84 F112 L125 W148 C149 S156	L84-Q152 HydrophobicContact CD1-CB 4.07Å; F112-Q152 VanDerWaalsContact CD1-NE2 3.29Å; F112-Q152 VanDerWaalsContact CE1-NE2 3.35Å; L125-Q152 HydrophobicContact CD1-CB 4.3Å; L125-Q152 HydrophobicContact CD1-CG 3.98Å; L125-Q152 HydrophobicContact CD2-CB 4.34Å; L125-Q152 HydrophobicContact CD2-CG 4.01Å; W148-Q152 HydrophobicContact CD2-CG 4.44Å; W148-Q152 HydrophobicContact CZ2-CG 4.35Å; W148-Q152 VanDerWaalsContact NE1-NE2 3.14Å; W148-Q152 WeakPolarHBondContact O-CG 3.45Å; W148-Q152 PolarHBondContact O-N 2.59Å; C149-Q152 PolarHBondContact O-N 2.91Å; Q152-S156 VanDerWaalsContact O-CB 3.31Å; Q152-S156 WeakPolarHBondContact O-CB 3.43Å; Q152-S156 PolarHBondContact O-N 3.33Å; Q152-S156 PolarHBondContact O-OG 3.14Å
153	F	83.4	Confident	82.8	Confident	2 Å²	2	57 Å²	57	1%	0.009	27%	0.274	C	S	.	.	H	α-helix	trans	-57.3	-55.5	175.1	156.5	-114.8	0	0	0	112.1	L137 F143 C149 N150 F151 T155 S156 L157 A188 L189	L137-F153 HydrophobicContact CD1-CD2 3.78Å; F143-F153 HydrophobicContact CE1-CB 4.29Å; F143-F153 HydrophobicContact CZ-CB 4.45Å; C149-F153 VanDerWaalsContact O-CB 3.26Å; C149-F153 WeakPolarHBondContact O-CB 3.25Å; C149-F153 PolarHBondContact O-N 2.85Å; N150-F153 WeakPolarHBondContact O-CB 3.45Å; N150-F153 PolarHBondContact O-N 3.11Å; F151-F153 VanDerWaalsContact C-N 3.29Å; F151-F153 PolarHBondContact O-N 2.95Å; F153-T155 PolarHBondContact O-N 2.89Å; F153-S156 PolarHBondContact O-N 2.7Å; F153-L157 HydrophobicContact CE2-CB 4.35Å; F153-L157 HydrophobicContact CE2-CD2 3.86Å; F153-L157 HydrophobicContact CZ-CD2 3.94Å; F153-L157 VanDerWaalsContact O-CB 3.32Å; F153-L157 WeakPolarHBondContact O-CB 3.45Å; F153-L157 PolarHBondContact O-N 2.92Å; F153-A188 HydrophobicContact CZ-CB 4.31Å; F153-L189 HydrophobicContact CD2-CD1 3.95Å; F153-L189 HydrophobicContact CD2-CD2 3.99Å; F153-L189 HydrophobicContact CD2-CG 4.1Å; F153-L189 HydrophobicContact CE2-CD1 3.78Å; F153-L189 HydrophobicContact CE2-CD2 3.38Å; F153-L189 HydrophobicContact CE2-CG 3.43Å; F153-L189 VanDerWaalsContact CE2-CG 3.43Å; F153-L189 HydrophobicContact CZ-CD2 4.36Å; F153-L189 HydrophobicContact CZ-CG 4.08Å
154	Y	86	Confident	83	Confident	134 Å²	134	65.8 Å²	65.8	53%	0.525	32%	0.315	S	S	.	.	H	α-helix	trans	-64.5	-41.2	-177.7	-77.4	-64.3	0	0	0	112.3	N150 F151 L157 M158	N150-Y154 WeakPolarHBondContact O-CD2 3.47Å; N150-Y154 PolarHBondContact O-N 3.45Å; F151-Y154 PolarHBondContact O-N 2.8Å; Y154-L157 PolarHBondContact O-N 2.94Å; Y154-M158 VanDerWaalsContact O-CB 3.31Å; Y154-M158 WeakPolarHBondContact O-CB 3.34Å; Y154-M158 WeakPolarHBondContact O-CG 3.23Å; Y154-M158 PolarHBondContact O-N 3.05Å
155	T	86.6	Confident	83.3	Confident	39 Å²	39	66.8 Å²	66.8	24%	0.239	32%	0.319	C	S	.	.	H	α-helix	trans	-62.5	-47.7	179.1	-59.8	0	0	0	0	111	L125 F151 F153 M158 N159	L125-T155 HydrophobicContact CD2-CG2 3.89Å; F151-T155 WeakPolarHBondContact CE1-OG1 3.4Å; F151-T155 WeakPolarHBondContact CZ-OG1 3.38Å; F151-T155 WeakPolarHBondContact O-CB 3.41Å; F151-T155 PolarHBondContact O-N 3.43Å; F151-T155 PolarHBondContact O-OG1 2.97Å; F153-T155 PolarHBondContact O-N 2.89Å; T155-M158 PolarHBondContact O-N 3.49Å; T155-N159 VanDerWaalsContact O-CB 3.29Å; T155-N159 WeakPolarHBondContact O-CB 3.29Å; T155-N159 PolarHBondContact O-N 2.49Å
156	S	86.2	Confident	83.8	Confident	0 Å²	0	58.6 Å²	58.6	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-63.7	-44.5	178.9	-54.6	0	0	0	0	111.5	L84 V129 Q152 F153 N159 S160 V170	L84-S156 VanDerWaalsContact CD1-OG 3.27Å; L84-S156 WeakPolarHBondContact CD1-OG 3.31Å; V129-S156 WeakPolarHBondContact CG2-OG 3.39Å; Q152-S156 VanDerWaalsContact O-CB 3.31Å; Q152-S156 WeakPolarHBondContact O-CB 3.43Å; Q152-S156 PolarHBondContact O-N 3.33Å; Q152-S156 PolarHBondContact O-OG 3.14Å; F153-S156 PolarHBondContact O-N 2.7Å; S156-N159 WeakPolarHBondContact O-CB 3.27Å; S156-N159 PolarHBondContact O-N 3.09Å; S156-S160 PolarHBondContact O-N 2.97Å; S156-V170 WeakPolarHBondContact O-CG2 3.37Å
157	L	88.1	Confident	84.2	Confident	16 Å²	16	63.9 Å²	63.9	8%	0.084	31%	0.305	C	S	.	.	H	α-helix	trans	-63.4	-48.9	178.7	-176.2	63	0	0	0	111.4	F153 Y154 N159 S160 V161 A188 I192	F153-L157 HydrophobicContact CE2-CB 4.35Å; F153-L157 HydrophobicContact CE2-CD2 3.86Å; F153-L157 HydrophobicContact CZ-CD2 3.94Å; F153-L157 VanDerWaalsContact O-CB 3.32Å; F153-L157 WeakPolarHBondContact O-CB 3.45Å; F153-L157 PolarHBondContact O-N 2.92Å; Y154-L157 PolarHBondContact O-N 2.94Å; L157-N159 VanDerWaalsContact C-N 3.28Å; L157-N159 PolarHBondContact O-N 2.93Å; L157-S160 PolarHBondContact O-N 3.07Å; L157-S160 PolarHBondContact O-OG 2.8Å; L157-V161 WeakPolarHBondContact O-CG2 3.41Å; L157-V161 PolarHBondContact O-N 2.9Å; L157-V161 VanDerWaalsContact O-N 3.07Å; L157-A188 HydrophobicContact CD2-CB 3.92Å; L157-I192 HydrophobicContact CD1-CD1 3.79Å
158	M	87.4	Confident	84.6	Confident	88 Å²	88	62.8 Å²	62.8	43%	0.433	30%	0.295	S	S	.	.	H	α-helix	trans	-63.1	-35.6	178	-69	-59.6	103.5	0	0	111.8	Y154 T155 V161 N162	Y154-M158 VanDerWaalsContact O-CB 3.31Å; Y154-M158 WeakPolarHBondContact O-CB 3.34Å; Y154-M158 WeakPolarHBondContact O-CG 3.23Å; Y154-M158 PolarHBondContact O-N 3.05Å; T155-M158 PolarHBondContact O-N 3.49Å; M158-V161 PolarHBondContact O-N 3.03Å; M158-N162 VanDerWaalsContact O-CB 3.26Å; M158-N162 WeakPolarHBondContact O-CB 3.3Å; M158-N162 PolarHBondContact O-N 3.22Å; M158-N162 PolarHBondContact O-ND2 2.85Å
159	N	85.9	Confident	85.4	Confident	13 Å²	13	59.4 Å²	59.4	7%	0.07	28%	0.282	C	S	.	.	H	α-helix	trans	-59.7	-47.6	173.6	-173.3	-71.9	0	0	0	111.1	V129 N130 T155 S156 L157 V161 N162 R163	V129-N159 HydrophobicContact CG1-CB 3.94Å; N130-N159 PolarHBondContact OD1-ND2 3.26Å; T155-N159 VanDerWaalsContact O-CB 3.29Å; T155-N159 WeakPolarHBondContact O-CB 3.29Å; T155-N159 PolarHBondContact O-N 2.49Å; S156-N159 WeakPolarHBondContact O-CB 3.27Å; S156-N159 PolarHBondContact O-N 3.09Å; L157-N159 VanDerWaalsContact C-N 3.28Å; L157-N159 PolarHBondContact O-N 2.93Å; N159-V161 VanDerWaalsContact C-N 3.29Å; N159-V161 PolarHBondContact O-N 2.92Å; N159-N162 PolarHBondContact O-N 3.25Å; N159-R163 PolarHBondContact ND2-NE 3.34Å; N159-R163 WeakPolarHBondContact O-CB 3.41Å; N159-R163 PolarHBondContact O-N 2.83Å
160	S	86.2	Confident	86.1	Confident	7 Å²	7	59.5 Å²	59.5	5%	0.049	28%	0.283	C	S	.	.	H	α-helix	trans	-65.5	-28.9	179.3	75.3	0	0	0	0	114.4	S156 L157 K166 Y167	S156-S160 PolarHBondContact O-N 2.97Å; L157-S160 PolarHBondContact O-N 3.07Å; L157-S160 PolarHBondContact O-OG 2.8Å; S160-K166 WeakPolarHBondContact CA-O 3.36Å; S160-K166 WeakPolarHBondContact CB-O 3.29Å; S160-Y167 WeakPolarHBondContact O-CA 3.49Å
161	V	85.8	Confident	86.8	Confident	90 Å²	90	57.8 Å²	57.8	55%	0.545	27%	0.273	S	S	.	.	H	α-helix	trans	-80.4	-41.6	177.3	172.5	0	0	0	0	111.1	L157 M158 N159	L157-V161 WeakPolarHBondContact O-CG2 3.41Å; L157-V161 PolarHBondContact O-N 2.9Å; L157-V161 VanDerWaalsContact O-N 3.07Å; M158-V161 PolarHBondContact O-N 3.03Å; N159-V161 VanDerWaalsContact C-N 3.29Å; N159-V161 PolarHBondContact O-N 2.92Å
162	N	85.9	Confident	87.3	Confident	128 Å²	128	53.9 Å²	53.9	68%	0.684	26%	0.256	S	S	*	.	H	α-helix	trans	-81.9	-23.6	-173.9	-67.8	-31.9	0	0	0	113.2	M158 N159	M158-N162 VanDerWaalsContact O-CB 3.26Å; M158-N162 WeakPolarHBondContact O-CB 3.3Å; M158-N162 PolarHBondContact O-N 3.22Å; M158-N162 PolarHBondContact O-ND2 2.85Å; N159-N162 PolarHBondContact O-N 3.25Å
163	R	84.8	Confident	88	Confident	90 Å²	90	53.8 Å²	53.8	34%	0.34	26%	0.256	S	S	.	.			trans	-107.3	113.2	-179.5	-62.3	-173.2	-177.3	-160.1	9.1	110.7	N130 N159 H165 K166 Y167	N130-R163 VanDerWaalsContact CG-NH1 3.29Å; N130-R163 PolarHBondContact ND2-NH1 2.93Å; N130-R163 PolarHBondContact ND2-NH2 3.38Å; N130-R163 VanDerWaalsContact OD1-CZ 3.24Å; N130-R163 PolarHBondContact OD1-NH1 3.41Å; N159-R163 PolarHBondContact ND2-NE 3.34Å; N159-R163 WeakPolarHBondContact O-CB 3.41Å; N159-R163 PolarHBondContact O-N 2.83Å; R163-H165 VanDerWaalsContact C-N 3.26Å; R163-H165 PolarHBondContact O-N 2.91Å; R163-H165 VanDerWaalsContact O-N 3.17Å; R163-K166 HydrophobicContact CB-CB 3.99Å; R163-K166 HydrophobicContact CB-CG 3.94Å; R163-K166 CarbonylContact O-C 3.53Å; R163-K166 WeakPolarHBondContact O-CA 3.48Å; R163-K166 PolarHBondContact O-N 2.6Å; R163-Y167 PolarHBondContact O-N 2.86Å
164	Q	82.8	Confident	88.5	Confident	184 Å²	184	54.9 Å²	54.9	86%	0.86	26%	0.26	S	S	*	.	G	3₁₀ helix	trans	-55.8	-38.5	-176.7	-172.8	177.1	-2.4	0	0	113.4	K166 Y167	Q164-K166 PolarHBondContact O-N 2.98Å; Q164-Y167 WeakPolarHBondContact O-CB 3.38Å; Q164-Y167 PolarHBondContact O-N 3.39Å
165	H	82.8	Confident	89	Confident	61 Å²	61	48.6 Å²	48.6	28%	0.282	24%	0.236	S	C	.	.	G	3₁₀ helix	trans	-74.8	-9.2	178.9	64.8	-89	0	0	0	114	R163 Q218 I221	R163-H165 VanDerWaalsContact C-N 3.26Å; R163-H165 PolarHBondContact O-N 2.91Å; R163-H165 VanDerWaalsContact O-N 3.17Å; H165-Q218 VanDerWaalsContact O-CD 3.29Å; H165-Q218 VanDerWaalsContact O-CG 3.31Å; H165-Q218 WeakPolarHBondContact O-CG 3.35Å; H165-I221 HydrophobicContact CB-CD1 3.46Å; H165-I221 VanDerWaalsContact CB-CD1 3.46Å; H165-I221 HydrophobicContact CB-CG2 4.18Å
166	K	88.9	Confident	89.3	Confident	3 Å²	3	51 Å²	51	1%	0.013	25%	0.246	C	C	.	.	G	3₁₀ helix	trans	-106.2	7	175.3	-63.1	-73.9	-179.4	165.4	0	112.1	V129 N130 S132 S160 R163 Q164 N168 S169	V129-K166 PolarHBondContact O-NZ 2.87Å; N130-K166 PolarHBondContact O-NZ 3.39Å; S132-K166 PolarHBondContact O-NZ 3.37Å; S160-K166 WeakPolarHBondContact CA-O 3.36Å; S160-K166 WeakPolarHBondContact CB-O 3.29Å; R163-K166 HydrophobicContact CB-CB 3.99Å; R163-K166 HydrophobicContact CB-CG 3.94Å; R163-K166 CarbonylContact O-C 3.53Å; R163-K166 WeakPolarHBondContact O-CA 3.48Å; R163-K166 PolarHBondContact O-N 2.6Å; Q164-K166 PolarHBondContact O-N 2.98Å; K166-N168 PolarHBondContact O-N 3.22Å; K166-S169 WeakPolarHBondContact O-CB 3.26Å; K166-S169 PolarHBondContact O-N 2.97Å; K166-S169 PolarHBondContact O-OG 2.86Å
167	Y	86.3	Confident	89.6	Confident	162 Å²	162	55.1 Å²	55.1	64%	0.635	27%	0.269	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.7	130.2	-179.8	-176.1	-109.9	0	0	0	111	S160 R163 Q164 S169	S160-Y167 WeakPolarHBondContact O-CA 3.49Å; R163-Y167 PolarHBondContact O-N 2.86Å; Q164-Y167 WeakPolarHBondContact O-CB 3.38Å; Q164-Y167 PolarHBondContact O-N 3.39Å; Y167-S169 PolarHBondContact O-N 3.14Å
168	N	86.1	Confident	89.7	Confident	97 Å²	97	58 Å²	58	52%	0.519	28%	0.284	S	S	.	.	T	Hydrogen-bonded Turn	trans	56.3	24.5	-174.2	-60.3	-28	0	0	0	115.1	K166	K166-N168 PolarHBondContact O-N 3.22Å
169	S	92.7	Very high	90	Very high	2 Å²	2	56.3 Å²	56.3	1%	0.014	28%	0.279	C	S	.	.			trans	-78.8	-20.2	174.3	60.4	0	0	0	0	113.7	A133 W134 T135 K166 Y167	A133-S169 VanDerWaalsContact O-CB 3.29Å; A133-S169 WeakPolarHBondContact O-CB 3.17Å; W134-S169 CarbonylContact C-O 3.39Å; W134-S169 VanDerWaalsContact CA-O 3.29Å; W134-S169 WeakPolarHBondContact CA-O 3.35Å; T135-S169 PolarHBondContact N-O 3.31Å; K166-S169 WeakPolarHBondContact O-CB 3.26Å; K166-S169 PolarHBondContact O-N 2.97Å; K166-S169 PolarHBondContact O-OG 2.86Å; Y167-S169 PolarHBondContact O-N 3.14Å
170	V	94.6	Very high	90.3	Very high	2 Å²	2	56 Å²	56	1%	0.012	28%	0.278	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.6	117.7	177.2	174.4	0	0	0	0	109.4	T135 L137 S156	T135-V170 CarbonylContact O-C 3.58Å; T135-V170 WeakPolarHBondContact O-CA 3.18Å; L137-V170 HydrophobicContact CD1-CG1 3.61Å; L137-V170 HydrophobicContact CG-CG1 3.95Å; S156-V170 WeakPolarHBondContact O-CG2 3.37Å
171	I	95.9	Very high	90.5	Very high	10 Å²	10	57.6 Å²	57.6	5%	0.051	29%	0.288	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.9	106.2	-175.7	-50.6	-57.6	0	0	0	108.5	W134 T135 I136 L137 M173 L195 I209	W134-I171 HydrophobicContact CB-CG1 4.4Å; T135-I171 PolarHBondContact O-N 3.46Å; I136-I171 CarbonylContact C-O 3.57Å; I136-I171 VanDerWaalsContact CA-O 3.3Å; I136-I171 WeakPolarHBondContact CA-O 3.37Å; I136-I171 HydrophobicContact CG1-CB 4.47Å; L137-I171 PolarHBondContact N-O 2.94Å; I171-M173 PolarHBondContact O-N 3.37Å; I171-L195 HydrophobicContact CG2-CB 3.92Å; I171-I209 HydrophobicContact CD1-CG2 3.56Å; I171-I209 HydrophobicContact CG1-CG2 3.74Å; I171-I209 HydrophobicContact CG2-CD1 4.02Å; I171-I209 HydrophobicContact CG2-CG2 4.43Å
172	P	95.2	Very high	90.7	Very high	1 Å²	1	59.5 Å²	59.5	1%	0.006	29%	0.286	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-67.7	130.6	170.3	-7.1	22.9	0	0	0	108.2	L139 L189 I192 A194 L195	L139-P172 HydrophobicContact CD1-CB 3.69Å; L139-P172 HydrophobicContact CG-CB 4.19Å; P172-L189 HydrophobicContact CG-CB 4.43Å; P172-L189 HydrophobicContact CG-CD2 4.05Å; P172-I192 HydrophobicContact CG-CB 4.01Å; P172-I192 HydrophobicContact CG-CG2 3.94Å; P172-A194 HydrophobicContact CB-CB 4.08Å; P172-A194 CarbonylContact O-C 3.57Å; P172-A194 WeakPolarHBondContact O-CA 3.49Å; P172-A194 WeakPolarHBondContact O-CB 3.31Å; P172-L195 PolarHBondContact O-N 3.42Å
173	M	95.8	Very high	90.8	Very high	0 Å²	0	61 Å²	61	0%	0	29%	0.289	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.7	127.9	-179.3	-178.1	-85.2	-179.1	0	0	110	V96 I136 L137 L138 L139 I171 P175 L195 E197	V96-M173 HydrophobicContact CB-CE 4.26Å; V96-M173 HydrophobicContact CG1-CE 3.67Å; V96-M173 HydrophobicContact CG1-SD 4.12Å; V96-M173 HydrophobicContact CG2-CE 3.47Å; V96-M173 VanDerWaalsContact CG2-CE 3.47Å; V96-M173 HydrophobicContact CG2-SD 4.15Å; I136-M173 HydrophobicContact CG2-CB 3.51Å; I136-M173 HydrophobicContact CG2-CG 4.25Å; L137-M173 PolarHBondContact O-N 3.43Å; L138-M173 HydrophobicContact CD1-SD 3.45Å; L138-M173 WeakPolarHBondContact CD1-SD 3.39Å; L139-M173 WeakPolarHBondContact CB-O 3.31Å; L139-M173 PolarHBondContact N-O 3.22Å; I171-M173 PolarHBondContact O-N 3.37Å; M173-P175 HydrophobicContact CE-CB 4.22Å; M173-P175 WeakPolarHBondContact O-CD 3.32Å; M173-P175 HydrophobicContact SD-CB 4.19Å; M173-L195 CarbonylContact C-O 3.58Å; M173-L195 VanDerWaalsContact CA-O 3.31Å; M173-L195 WeakPolarHBondContact CA-O 3.26Å; M173-L195 HydrophobicContact CB-CB 4.23Å; M173-L195 HydrophobicContact CG-CB 4.15Å; M173-L195 HydrophobicContact CG-CD2 4Å; M173-L195 HydrophobicContact CG-CG 4.18Å; M173-E197 HydrophobicContact CE-CB 4.1Å; M173-E197 VanDerWaalsContact CE-OE2 3.25Å; M173-E197 WeakPolarHBondContact CE-OE2 3.49Å
174	R	95.4	Very high	91	Very high	25 Å²	25	63.4 Å²	63.4	9%	0.094	30%	0.298	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.9	111.3	173.8	-69.9	-170	-177.2	81.3	11	109	L139 T185 L195 E196 E197	L139-R174 HydrophobicContact CB-CG 4.22Å; L139-R174 HydrophobicContact CD1-CG 4.12Å; R174-T185 PolarHBondContact NH2-OG1 3.43Å; R174-L195 PolarHBondContact N-O 2.87Å; R174-E196 IonicContact NH1-OE1 3.54Å; R174-E197 PolarHBondContact O-N 3.35Å
175	P	95.9	Very high	91.3	Very high	3 Å²	3	54.9 Å²	54.9	2%	0.019	26%	0.258	C	S	.	.			trans	-71	166.9	177.8	25.6	-29.7	0	0	0	112.3	E92 L138 T140 M173 N177 P179	E92-P175 HydrophobicContact CG-CB 3.89Å; E92-P175 HydrophobicContact CG-CG 4.28Å; E92-P175 WeakPolarHBondContact OE1-CB 3.31Å; L138-P175 HydrophobicContact CD1-CB 4.09Å; L138-P175 HydrophobicContact CD1-CG 3.92Å; L138-P175 HydrophobicContact CG-CG 4.36Å; T140-P175 HydrophobicContact CG2-CG 3.99Å; M173-P175 HydrophobicContact CE-CB 4.22Å; M173-P175 WeakPolarHBondContact O-CD 3.32Å; M173-P175 HydrophobicContact SD-CB 4.19Å; P175-N177 WeakPolarHBondContact CG-O 3.34Å; P175-P179 WeakPolarHBondContact O-CB 3.38Å
176	L	93.6	Very high	91.5	Very high	88 Å²	88	53.6 Å²	53.6	46%	0.461	26%	0.255	S	S	.	.	S	Bend	trans	-65.7	-38.7	169.2	-71.1	170.9	0	0	0	112.3	E197 E198	L176-E197 HydrophobicContact CD1-CG 4Å; L176-E197 WeakPolarHBondContact CD1-OE1 3.48Å; L176-E197 HydrophobicContact CD2-CB 4.26Å; L176-E197 HydrophobicContact CD2-CG 4.17Å; L176-E197 HydrophobicContact CG-CB 4Å; L176-E197 VanDerWaalsContact CG-CD 3.4Å; L176-E197 HydrophobicContact CG-CG 3.65Å; L176-E197 WeakPolarHBondContact CG-OE1 3.37Å; L176-E197 PolarHBondContact N-OE2 3.48Å; L176-E198 HydrophobicContact CD2-CB 4.07Å
177	N	92.4	Very high	91.4	Very high	88 Å²	88	61 Å²	61	47%	0.471	29%	0.287	S	S	.	.	S	Bend	trans	-95.6	130.3	-175	-58.1	-47.2	0	0	0	110.9	E92 P175 P179	E92-N177 PolarHBondContact OE1-ND2 3.06Å; E92-N177 PolarHBondContact OE2-ND2 2.94Å; P175-N177 WeakPolarHBondContact CG-O 3.34Å; N177-P179 VanDerWaalsContact C-CD 3.47Å
178	N	89.9	Confident	91.4	Very high	77 Å²	77	55 Å²	55	41%	0.412	27%	0.271	S	S	.	.	S	Bend	trans	49	47.6	177.4	-166.3	32.4	0	0	0	114.7	T140 E141	T140-N178 WeakPolarHBondContact CA-O 3.48Å; E141-N178 WeakPolarHBondContact CG-OD1 3.45Å; E141-N178 PolarHBondContact N-O 2.73Å
179	P	93.3	Very high	91.3	Very high	51 Å²	51	50.4 Å²	50.4	33%	0.331	25%	0.247	S	C	.	.	B	Isolated β-bridge	trans	-66.1	141.7	-177.5	26.8	-33.5	0	0	0	111.4	P175 N177 P181	P175-P179 WeakPolarHBondContact O-CB 3.38Å; N177-P179 VanDerWaalsContact C-CD 3.47Å; P179-P181 WeakPolarHBondContact O-CD 3.21Å
180	L	91.6	Very high	91.1	Very high	6 Å²	6	55 Å²	55	3%	0.031	27%	0.268	C	S	.	.	P	Polyproline II helix	trans	-66.6	123.9	170.4	-175.6	73.1	0	0	0	110.5	L139 L144 R184	L139-L180 HydrophobicContact CB-CB 4.03Å; L139-L180 HydrophobicContact CB-CD2 4.45Å; L139-L180 VanDerWaalsContact O-CB 3.31Å; L139-L180 WeakPolarHBondContact O-CB 3.38Å; L139-L180 PolarHBondContact O-N 3.4Å; L144-L180 HydrophobicContact CD1-CD1 3.95Å; L144-L180 HydrophobicContact CD1-CD2 3.37Å; L144-L180 HydrophobicContact CD1-CG 4.3Å; L144-L180 HydrophobicContact CG-CD1 4.49Å; L144-L180 HydrophobicContact CG-CD2 3.92Å; L180-R184 HydrophobicContact CD1-CB 3.85Å; L180-R184 HydrophobicContact CG-CB 4.26Å
181	P	90.9	Very high	90.7	Very high	42 Å²	42	59.7 Å²	59.7	27%	0.273	30%	0.297	S	S	.	.	P	Polyproline II helix	trans	-57.3	145.9	174.7	-24.5	34.2	0	0	0	112.2	P179 E183 R184 T185	P179-P181 WeakPolarHBondContact O-CD 3.21Å; P181-E183 VanDerWaalsContact CB-OE2 3.23Å; P181-E183 WeakPolarHBondContact CB-OE2 3.1Å; P181-E183 PolarHBondContact O-N 3.44Å; P181-R184 PolarHBondContact O-N 2.99Å; P181-T185 PolarHBondContact O-N 3.34Å; P181-T185 VanDerWaalsContact O-N 3.16Å; P181-T185 PolarHBondContact O-OG1 3.03Å
182	R	89.4	Confident	90.5	Very high	129 Å²	129	61.1 Å²	61.1	49%	0.487	30%	0.304	S	S	.	.	G	3₁₀ helix	trans	-60.4	-35.6	-178	-67.2	-171.6	-169.8	-101.4	3.3	111.9	R184 T185 Q190 E196	R182-R184 PolarHBondContact O-N 3.46Å; R182-T185 VanDerWaalsContact O-CB 3.26Å; R182-T185 WeakPolarHBondContact O-CB 3.31Å; R182-T185 PolarHBondContact O-N 3.44Å; R182-T185 PolarHBondContact O-OG1 3.34Å; R182-Q190 PolarHBondContact O-NE2 3.15Å; R182-Q190 VanDerWaalsContact O-NE2 3.08Å; R182-E196 IonicContact CZ-OE1 3.06Å; R182-E196 IonicContact CZ-OE2 3.79Å; R182-E196 IonicContact NH1-OE1 2.75Å; R182-E196 PolarHBondContact NH1-OE1 3.38Å; R182-E196 IonicContact NH2-OE1 2.68Å; R182-E196 PolarHBondContact NH2-OE1 3.06Å; R182-E196 IonicContact NH2-OE2 2.72Å; R182-E196 PolarHBondContact NH2-OE2 3.36Å
183	E	89.2	Confident	90.2	Very high	160 Å²	160	67.1 Å²	67.1	75%	0.748	34%	0.336	S	S	*	.	G	3₁₀ helix	trans	-64.6	-28.5	-179.4	-54	72.1	-154.3	0	0	111.7	P181	P181-E183 VanDerWaalsContact CB-OE2 3.23Å; P181-E183 WeakPolarHBondContact CB-OE2 3.1Å; P181-E183 PolarHBondContact O-N 3.44Å
184	R	88.3	Confident	90.1	Very high	141 Å²	141	67.5 Å²	67.5	53%	0.532	34%	0.34	S	S	.	.	G	3₁₀ helix	trans	-92.2	-10.6	175.8	-65.6	-173.4	179.7	162.9	2.2	113.1	E141 L144 L180 P181 R182	E141-R184 IonicContact OE1-NH1 3.69Å; E141-R184 PolarHBondContact OE1-NH1 2.94Å; E141-R184 IonicContact OE2-NH1 3.29Å; L144-R184 VanDerWaalsContact CD1-O 3.25Å; L144-R184 WeakPolarHBondContact CD1-O 3.41Å; L180-R184 HydrophobicContact CD1-CB 3.85Å; L180-R184 HydrophobicContact CG-CB 4.26Å; P181-R184 PolarHBondContact O-N 2.99Å; R182-R184 PolarHBondContact O-N 3.46Å
185	T	88.8	Confident	90.1	Very high	5 Å²	5	66.3 Å²	66.3	3%	0.031	34%	0.335	C	S	.	.	S	Bend	trans	-66.1	132.4	177.7	-57.6	0	0	0	0	109.2	L139 R174 P181 R182 L189 Q190	L139-T185 HydrophobicContact CD1-CG2 4.29Å; R174-T185 PolarHBondContact NH2-OG1 3.43Å; P181-T185 PolarHBondContact O-N 3.34Å; P181-T185 VanDerWaalsContact O-N 3.16Å; P181-T185 PolarHBondContact O-OG1 3.03Å; R182-T185 VanDerWaalsContact O-CB 3.26Å; R182-T185 WeakPolarHBondContact O-CB 3.31Å; R182-T185 PolarHBondContact O-N 3.44Å; R182-T185 PolarHBondContact O-OG1 3.34Å; T185-L189 HydrophobicContact CG2-CB 3.72Å; T185-Q190 HydrophobicContact CG2-CG 3.96Å; T185-Q190 PolarHBondContact O-NE2 2.95Å
186	P	87.1	Confident	90.1	Very high	33 Å²	33	68.1 Å²	68.1	21%	0.214	34%	0.343	C	S	.	.			trans	-60.5	142.8	179	-21.8	34.7	0	0	0	110.7	L144 A188 L189 Q190	L144-P186 HydrophobicContact CD1-CG 4.12Å; L144-P186 HydrophobicContact CD2-CG 3.78Å; P186-A188 PolarHBondContact O-N 3.05Å; P186-A188 VanDerWaalsContact O-N 3.11Å; P186-L189 PolarHBondContact O-N 3.18Å; P186-Q190 PolarHBondContact O-N 2.88Å; P186-Q190 VanDerWaalsContact O-N 3.12Å
187	F	87.1	Confident	90.2	Very high	158 Å²	158	65 Å²	65	69%	0.693	33%	0.326	S	S	*	.	H	α-helix	trans	-51.9	-41	-174.3	179.7	-102.1	0	0	0	113.3	L189 Q190 T191	F187-L189 PolarHBondContact O-N 3.31Å; F187-Q190 WeakPolarHBondContact O-CB 3.29Å; F187-Q190 PolarHBondContact O-N 3.17Å; F187-Q190 VanDerWaalsContact O-N 3.09Å; F187-T191 HydrophobicContact CE1-CG2 4.23Å; F187-T191 HydrophobicContact CZ-CG2 4.22Å; F187-T191 PolarHBondContact O-N 2.86Å
188	A	86	Confident	90.3	Very high	36 Å²	36	68.9 Å²	68.9	30%	0.298	34%	0.341	S	S	.	.	H	α-helix	trans	-61.9	-28.7	178.5	0	0	0	0	0	113.8	F153 L157 P186 T191	F153-A188 HydrophobicContact CZ-CB 4.31Å; L157-A188 HydrophobicContact CD2-CB 3.92Å; P186-A188 PolarHBondContact O-N 3.05Å; P186-A188 VanDerWaalsContact O-N 3.11Å; A188-T191 PolarHBondContact O-OG1 3.29Å
189	L	85.4	Confident	90.5	Very high	1 Å²	1	67.4 Å²	67.4	1%	0.005	34%	0.337	C	S	.	.	H	α-helix	trans	-86	-26.9	174.6	-66	-172.2	0	0	0	112.4	L137 L139 F153 P172 T185 P186 F187 T191 I192	L137-L189 HydrophobicContact CD1-CD1 4.18Å; L137-L189 HydrophobicContact CD1-CD2 4.04Å; L139-L189 HydrophobicContact CD2-CD1 3.81Å; F153-L189 HydrophobicContact CD2-CD1 3.95Å; F153-L189 HydrophobicContact CD2-CD2 3.99Å; F153-L189 HydrophobicContact CD2-CG 4.1Å; F153-L189 HydrophobicContact CE2-CD1 3.78Å; F153-L189 HydrophobicContact CE2-CD2 3.38Å; F153-L189 HydrophobicContact CE2-CG 3.43Å; F153-L189 VanDerWaalsContact CE2-CG 3.43Å; F153-L189 HydrophobicContact CZ-CD2 4.36Å; F153-L189 HydrophobicContact CZ-CG 4.08Å; P172-L189 HydrophobicContact CG-CB 4.43Å; P172-L189 HydrophobicContact CG-CD2 4.05Å; T185-L189 HydrophobicContact CG2-CB 3.72Å; P186-L189 PolarHBondContact O-N 3.18Å; F187-L189 PolarHBondContact O-N 3.31Å; L189-T191 PolarHBondContact O-N 3.34Å; L189-I192 HydrophobicContact CD2-CD1 4.11Å; L189-I192 PolarHBondContact O-N 3.34Å; L189-I192 VanDerWaalsContact O-N 3.1Å; L189-I192 VanDerWaalsContact O-O 3.13Å
190	Q	87.1	Confident	90.6	Very high	100 Å²	100	77 Å²	77	47%	0.467	37%	0.367	S	S	.	.	H	α-helix	trans	-63.8	-25.9	173.5	-63.9	-177.1	9.6	0	0	112	R182 T185 P186 F187 I192	R182-Q190 PolarHBondContact O-NE2 3.15Å; R182-Q190 VanDerWaalsContact O-NE2 3.08Å; T185-Q190 HydrophobicContact CG2-CG 3.96Å; T185-Q190 PolarHBondContact O-NE2 2.95Å; P186-Q190 PolarHBondContact O-N 2.88Å; P186-Q190 VanDerWaalsContact O-N 3.12Å; F187-Q190 WeakPolarHBondContact O-CB 3.29Å; F187-Q190 PolarHBondContact O-N 3.17Å; F187-Q190 VanDerWaalsContact O-N 3.09Å; Q190-I192 VanDerWaalsContact C-N 3.27Å
191	T	87.4	Confident	90.8	Very high	99 Å²	99	77.9 Å²	77.9	61%	0.607	38%	0.378	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.6	-7.8	176.1	59	0	0	0	0	113.7	F187 A188 L189	F187-T191 HydrophobicContact CE1-CG2 4.23Å; F187-T191 HydrophobicContact CZ-CG2 4.22Å; F187-T191 PolarHBondContact O-N 2.86Å; A188-T191 PolarHBondContact O-OG1 3.29Å; L189-T191 PolarHBondContact O-N 3.34Å
192	I	90.1	Very high	91	Very high	41 Å²	41	76.6 Å²	76.6	21%	0.21	37%	0.368	C	S	.	.	S	Bend	trans	-105.4	141.9	179.2	-56.1	172.7	0	0	0	108.4	L157 P172 L189 Q190 A194	L157-I192 HydrophobicContact CD1-CD1 3.79Å; P172-I192 HydrophobicContact CG-CB 4.01Å; P172-I192 HydrophobicContact CG-CG2 3.94Å; L189-I192 HydrophobicContact CD2-CD1 4.11Å; L189-I192 PolarHBondContact O-N 3.34Å; L189-I192 VanDerWaalsContact O-N 3.1Å; L189-I192 VanDerWaalsContact O-O 3.13Å; Q190-I192 VanDerWaalsContact C-N 3.27Å; I192-A194 PolarHBondContact O-N 2.9Å
193	N	89.4	Confident	91.4	Very high	127 Å²	127	73.1 Å²	73.1	68%	0.679	36%	0.362	S	S	*	.			trans	-66.5	109.6	175.4	-67.5	-34.2	0	0	0	109.3
194	A	93.8	Very high	91.8	Very high	8 Å²	8	70 Å²	70	7%	0.066	35%	0.354	C	S	.	.			trans	-78	139.9	175.4	0	0	0	0	0	110.3	P172 I192 E196 Q205	P172-A194 HydrophobicContact CB-CB 4.08Å; P172-A194 CarbonylContact O-C 3.57Å; P172-A194 WeakPolarHBondContact O-CA 3.49Å; P172-A194 WeakPolarHBondContact O-CB 3.31Å; I192-A194 PolarHBondContact O-N 2.9Å; A194-E196 HydrophobicContact CB-CG 4.5Å; A194-Q205 PolarHBondContact O-OE1 3.38Å
195	L	96.1	Very high	92.2	Very high	0 Å²	0	65.4 Å²	65.4	0%	0	34%	0.339	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-75.9	119.1	168.2	-179.3	62.8	0	0	0	108.9	I171 P172 M173 R174 F202 Q205 V206 I209 F210	I171-L195 HydrophobicContact CG2-CB 3.92Å; P172-L195 PolarHBondContact O-N 3.42Å; M173-L195 CarbonylContact C-O 3.58Å; M173-L195 VanDerWaalsContact CA-O 3.31Å; M173-L195 WeakPolarHBondContact CA-O 3.26Å; M173-L195 HydrophobicContact CB-CB 4.23Å; M173-L195 HydrophobicContact CG-CB 4.15Å; M173-L195 HydrophobicContact CG-CD2 4Å; M173-L195 HydrophobicContact CG-CG 4.18Å; R174-L195 PolarHBondContact N-O 2.87Å; L195-F202 HydrophobicContact CD1-CD2 3.57Å; L195-F202 HydrophobicContact CD1-CE2 3.62Å; L195-F202 HydrophobicContact CD2-CE2 3.84Å; L195-F202 HydrophobicContact CG-CD2 3.95Å; L195-F202 HydrophobicContact CG-CE2 3.6Å; L195-Q205 HydrophobicContact CD1-CB 3.55Å; L195-V206 HydrophobicContact CD1-CG2 3.87Å; L195-V206 HydrophobicContact CD2-CG2 4.34Å; L195-I209 HydrophobicContact CB-CD1 4.38Å; L195-I209 HydrophobicContact CD1-CD1 4.31Å; L195-F210 HydrophobicContact CD2-CE2 4.15Å; L195-F210 HydrophobicContact CD2-CZ 4.49Å
196	E	95.6	Very high	92.5	Very high	40 Å²	40	65.2 Å²	65.2	19%	0.187	34%	0.338	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.8	110.5	-172.8	-68	177	-161.1	0	0	111	R174 R182 A194 S199 F202	R174-E196 IonicContact NH1-OE1 3.54Å; R182-E196 IonicContact CZ-OE1 3.06Å; R182-E196 IonicContact CZ-OE2 3.79Å; R182-E196 IonicContact NH1-OE1 2.75Å; R182-E196 PolarHBondContact NH1-OE1 3.38Å; R182-E196 IonicContact NH2-OE1 2.68Å; R182-E196 PolarHBondContact NH2-OE1 3.06Å; R182-E196 IonicContact NH2-OE2 2.72Å; R182-E196 PolarHBondContact NH2-OE2 3.36Å; A194-E196 HydrophobicContact CB-CG 4.5Å; E196-S199 VanDerWaalsContact O-CB 3.31Å; E196-S199 WeakPolarHBondContact O-CB 3.39Å; E196-S199 PolarHBondContact O-N 2.92Å; E196-F202 WeakPolarHBondContact O-CB 3.17Å; E196-F202 WeakPolarHBondContact O-CD2 3.43Å
197	E	95.4	Very high	92.9	Very high	22 Å²	22	70.3 Å²	70.3	10%	0.103	36%	0.358	C	S	.	.	T	Hydrogen-bonded Turn	trans	-72.1	-34.1	-174.9	-162.3	-179.8	164.2	0	0	113.4	R95 L99 M173 R174 L176 S199 F202	R95-E197 IonicContact CZ-OE1 3.55Å; R95-E197 IonicContact CZ-OE2 2.63Å; R95-E197 IonicContact NH1-OE1 3.83Å; R95-E197 PolarHBondContact NH1-OE1 3.19Å; R95-E197 IonicContact NH1-OE2 2.83Å; R95-E197 VanDerWaalsContact NH2-CD 3.27Å; R95-E197 IonicContact NH2-OE1 3.05Å; R95-E197 PolarHBondContact NH2-OE1 2.75Å; R95-E197 VanDerWaalsContact NH2-OE1 3.07Å; R95-E197 IonicContact NH2-OE2 4Å; R95-E197 PolarHBondContact NH2-OE2 2.89Å; L99-E197 HydrophobicContact CD2-CG 4.12Å; L99-E197 VanDerWaalsContact CD2-OE1 3.25Å; L99-E197 WeakPolarHBondContact CD2-OE1 3.32Å; M173-E197 HydrophobicContact CE-CB 4.1Å; M173-E197 VanDerWaalsContact CE-OE2 3.25Å; M173-E197 WeakPolarHBondContact CE-OE2 3.49Å; R174-E197 PolarHBondContact O-N 3.35Å; L176-E197 HydrophobicContact CD1-CG 4Å; L176-E197 WeakPolarHBondContact CD1-OE1 3.48Å; L176-E197 HydrophobicContact CD2-CB 4.26Å; L176-E197 HydrophobicContact CD2-CG 4.17Å; L176-E197 HydrophobicContact CG-CB 4Å; L176-E197 VanDerWaalsContact CG-CD 3.4Å; L176-E197 HydrophobicContact CG-CG 3.65Å; L176-E197 WeakPolarHBondContact CG-OE1 3.37Å; L176-E197 PolarHBondContact N-OE2 3.48Å; E197-S199 PolarHBondContact O-N 3.47Å; E197-F202 HydrophobicContact CB-CD2 4.24Å; E197-F202 HydrophobicContact CB-CE2 4.17Å; E197-F202 HydrophobicContact CG-CD2 4.44Å; E197-F202 HydrophobicContact CG-CE1 4.28Å; E197-F202 HydrophobicContact CG-CE2 4.2Å; E197-F202 HydrophobicContact CG-CZ 4.13Å
198	E	94.3	Very high	93.3	Very high	170 Å²	170	71.5 Å²	71.5	79%	0.794	36%	0.359	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.1	-20.3	174.5	-167.9	-176.7	-166.7	0	0	112.3	L176	L176-E198 HydrophobicContact CD2-CB 4.07Å
199	S	94.7	Very high	93.8	Very high	47 Å²	47	71.4 Å²	71.4	33%	0.329	35%	0.352	S	S	.	.	S	Bend	trans	-73.7	136.1	-177.4	-178.1	0	0	0	0	111.6	E196 E197 G201 F202	E196-S199 VanDerWaalsContact O-CB 3.31Å; E196-S199 WeakPolarHBondContact O-CB 3.39Å; E196-S199 PolarHBondContact O-N 2.92Å; E197-S199 PolarHBondContact O-N 3.47Å; S199-G201 PolarHBondContact O-N 2.98Å; S199-G201 PolarHBondContact OG-N 3.36Å; S199-F202 WeakPolarHBondContact O-CB 3.25Å; S199-F202 PolarHBondContact O-N 3.34Å
200	R	94.9	Very high	94.2	Very high	251 Å²	251	72 Å²	72	95%	0.947	36%	0.355	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.1	-22.3	170.4	-63.7	-174.4	-179.2	-169.5	-0.2	113.2	F202	R200-F202 VanDerWaalsContact C-N 3.3Å
201	G	95.5	Very high	94.6	Very high	26 Å²	26	71.3 Å²	71.3	27%	0.268	35%	0.352	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.1	2.5	176	0	0	0	0	0	114.2	S199 T204 Q205	S199-G201 PolarHBondContact O-N 2.98Å; S199-G201 PolarHBondContact OG-N 3.36Å; G201-T204 PolarHBondContact O-N 3.05Å; G201-Q205 WeakPolarHBondContact O-CG 3.15Å; G201-Q205 PolarHBondContact O-N 2.98Å
202	F	96.5	Very high	95	Very high	14 Å²	14	70.3 Å²	70.3	6%	0.061	34%	0.34	C	S	.	.	H	α-helix	trans	-50.2	-51.3	-178.2	177.2	-109.8	0	0	0	113.3	L99 F104 L195 E196 E197 S199 R200 T204 Q205 V206	L99-F202 HydrophobicContact CD2-CE1 3.84Å; L99-F202 HydrophobicContact CD2-CZ 3.71Å; L99-F202 HydrophobicContact CG-CE1 4.33Å; L99-F202 HydrophobicContact CG-CZ 4.41Å; F104-F202 HydrophobicContact CD2-CE1 4.49Å; F104-F202 HydrophobicContact CE2-CD1 4.18Å; F104-F202 AromaticContact CE2-CE1 3.46Å; F104-F202 HydrophobicContact CE2-CE1 3.46Å; F104-F202 VanDerWaalsContact CE2-CE1 3.46Å; F104-F202 HydrophobicContact CE2-CZ 4.27Å; F104-F202 AromaticContact CZ-CD1 3.86Å; F104-F202 HydrophobicContact CZ-CD1 3.86Å; F104-F202 AromaticContact CZ-CE1 3.61Å; F104-F202 HydrophobicContact CZ-CE1 3.61Å; L195-F202 HydrophobicContact CD1-CD2 3.57Å; L195-F202 HydrophobicContact CD1-CE2 3.62Å; L195-F202 HydrophobicContact CD2-CE2 3.84Å; L195-F202 HydrophobicContact CG-CD2 3.95Å; L195-F202 HydrophobicContact CG-CE2 3.6Å; E196-F202 WeakPolarHBondContact O-CB 3.17Å; E196-F202 WeakPolarHBondContact O-CD2 3.43Å; E197-F202 HydrophobicContact CB-CD2 4.24Å; E197-F202 HydrophobicContact CB-CE2 4.17Å; E197-F202 HydrophobicContact CG-CD2 4.44Å; E197-F202 HydrophobicContact CG-CE1 4.28Å; E197-F202 HydrophobicContact CG-CE2 4.2Å; E197-F202 HydrophobicContact CG-CZ 4.13Å; S199-F202 WeakPolarHBondContact O-CB 3.25Å; S199-F202 PolarHBondContact O-N 3.34Å; R200-F202 VanDerWaalsContact C-N 3.3Å; F202-T204 VanDerWaalsContact C-N 3.33Å; F202-T204 PolarHBondContact O-N 3.44Å; F202-Q205 WeakPolarHBondContact O-CB 3.43Å; F202-Q205 PolarHBondContact O-N 3.21Å; F202-V206 HydrophobicContact CD1-CG2 4.45Å; F202-V206 HydrophobicContact CD2-CG2 4.26Å; F202-V206 HydrophobicContact CE1-CG2 4.11Å; F202-V206 HydrophobicContact CE2-CG2 3.92Å; F202-V206 HydrophobicContact CZ-CG2 3.83Å; F202-V206 WeakPolarHBondContact O-CG2 3.48Å; F202-V206 PolarHBondContact O-N 2.66Å
203	P	96.8	Very high	95.1	Very high	57 Å²	57	71.7 Å²	71.7	37%	0.37	35%	0.354	S	S	.	.	H	α-helix	trans	-58.1	-43.9	179.1	-26.5	37	0	0	0	113.2	F104 Q205 V206 E207	F104-P203 HydrophobicContact CE1-CB 3.86Å; F104-P203 HydrophobicContact CE1-CG 4.35Å; F104-P203 HydrophobicContact CZ-CB 4.31Å; F104-P203 HydrophobicContact CZ-CG 4.32Å; P203-Q205 VanDerWaalsContact C-N 3.3Å; P203-Q205 PolarHBondContact O-N 2.69Å; P203-V206 PolarHBondContact O-N 3.07Å; P203-E207 WeakPolarHBondContact O-CG 3.42Å; P203-E207 PolarHBondContact O-N 3.45Å
204	T	97.1	Very high	95.3	Very high	94 Å²	94	68.2 Å²	68.2	58%	0.577	34%	0.337	S	S	*	.	H	α-helix	trans	-64.9	-34.3	178.3	-51.7	0	0	0	0	112.1	G201 F202 R208	G201-T204 PolarHBondContact O-N 3.05Å; F202-T204 VanDerWaalsContact C-N 3.33Å; F202-T204 PolarHBondContact O-N 3.44Å; T204-R208 VanDerWaalsContact O-CB 3.24Å; T204-R208 WeakPolarHBondContact O-CB 3.49Å; T204-R208 PolarHBondContact O-N 3.3Å
205	Q	96.7	Very high	95.4	Very high	45 Å²	45	68.5 Å²	68.5	21%	0.21	34%	0.336	C	S	.	.	H	α-helix	trans	-67.1	-44.8	174.5	-69.7	177.8	100	0	0	111.1	A194 L195 G201 F202 P203 R208 I209	A194-Q205 PolarHBondContact O-OE1 3.38Å; L195-Q205 HydrophobicContact CD1-CB 3.55Å; G201-Q205 WeakPolarHBondContact O-CG 3.15Å; G201-Q205 PolarHBondContact O-N 2.98Å; F202-Q205 WeakPolarHBondContact O-CB 3.43Å; F202-Q205 PolarHBondContact O-N 3.21Å; P203-Q205 VanDerWaalsContact C-N 3.3Å; P203-Q205 PolarHBondContact O-N 2.69Å; Q205-R208 PolarHBondContact O-N 3Å; Q205-I209 HydrophobicContact CB-CD1 4.48Å; Q205-I209 WeakPolarHBondContact O-CB 3.49Å; Q205-I209 WeakPolarHBondContact O-CD1 3.47Å; Q205-I209 VanDerWaalsContact O-CG1 3.22Å; Q205-I209 WeakPolarHBondContact O-CG1 3.42Å; Q205-I209 PolarHBondContact O-N 3.2Å
206	V	96.6	Very high	95.3	Very high	1 Å²	1	73.1 Å²	73.1	1%	0.006	36%	0.357	C	S	.	.	H	α-helix	trans	-57.4	-52.7	176.5	176.6	0	0	0	0	110.1	L100 F104 I106 L195 F202 P203 R208 I209 F210	L100-V206 HydrophobicContact CD2-CG1 4.28Å; L100-V206 HydrophobicContact CD2-CG2 4.17Å; F104-V206 HydrophobicContact CB-CG1 3.81Å; F104-V206 HydrophobicContact CD1-CB 4.01Å; F104-V206 HydrophobicContact CD1-CG1 3.63Å; F104-V206 HydrophobicContact CD1-CG2 4.4Å; F104-V206 HydrophobicContact CD2-CG1 4.35Å; F104-V206 HydrophobicContact CE1-CB 4.19Å; F104-V206 HydrophobicContact CE1-CG1 4.3Å; F104-V206 HydrophobicContact CE1-CG2 4.31Å; F104-V206 HydrophobicContact CG-CB 4.39Å; F104-V206 HydrophobicContact CG-CG1 3.66Å; F104-V206 HydrophobicContact CZ-CG2 4.37Å; I106-V206 HydrophobicContact CG1-CG1 4.19Å; L195-V206 HydrophobicContact CD1-CG2 3.87Å; L195-V206 HydrophobicContact CD2-CG2 4.34Å; F202-V206 HydrophobicContact CD1-CG2 4.45Å; F202-V206 HydrophobicContact CD2-CG2 4.26Å; F202-V206 HydrophobicContact CE1-CG2 4.11Å; F202-V206 HydrophobicContact CE2-CG2 3.92Å; F202-V206 HydrophobicContact CZ-CG2 3.83Å; F202-V206 WeakPolarHBondContact O-CG2 3.48Å; F202-V206 PolarHBondContact O-N 2.66Å; P203-V206 PolarHBondContact O-N 3.07Å; V206-R208 VanDerWaalsContact C-N 3.28Å; V206-R208 PolarHBondContact O-N 3.23Å; V206-I209 PolarHBondContact O-N 2.81Å; V206-F210 HydrophobicContact CB-CD2 4.22Å; V206-F210 HydrophobicContact CG1-CD2 3.59Å; V206-F210 HydrophobicContact CG1-CE2 4.09Å; V206-F210 VanDerWaalsContact O-CD2 3.23Å; V206-F210 WeakPolarHBondContact O-CD2 3.47Å; V206-F210 PolarHBondContact O-N 3.22Å
207	E	95.4	Very high	95.2	Very high	139 Å²	139	75.2 Å²	75.2	65%	0.65	37%	0.372	S	S	*	.	H	α-helix	trans	-58.7	-39.1	178.8	-71.1	176.9	176.2	0	0	112.8	P203	P203-E207 WeakPolarHBondContact O-CG 3.42Å; P203-E207 PolarHBondContact O-N 3.45Å
208	R	95.3	Very high	95.1	Very high	184 Å²	184	74.5 Å²	74.5	69%	0.694	37%	0.369	S	S	*	.	H	α-helix	trans	-71.4	-35.8	-179.5	-176	177	179.4	-179.6	0.3	112.7	T204 Q205 V206 Q211	T204-R208 VanDerWaalsContact O-CB 3.24Å; T204-R208 WeakPolarHBondContact O-CB 3.49Å; T204-R208 PolarHBondContact O-N 3.3Å; Q205-R208 PolarHBondContact O-N 3Å; V206-R208 VanDerWaalsContact C-N 3.28Å; V206-R208 PolarHBondContact O-N 3.23Å; R208-Q211 WeakPolarHBondContact O-CG 3.36Å; R208-Q211 PolarHBondContact O-NE2 3.26Å
209	I	94.9	Very high	95.1	Very high	33 Å²	33	68 Å²	68	17%	0.169	34%	0.338	C	S	.	.	H	α-helix	trans	-81.2	-51.2	-176.6	-70.4	166.9	0	0	0	110.3	W134 I171 L195 Q205 V206 Q211	W134-I209 WeakPolarHBondContact CZ2-O 3.48Å; W134-I209 PolarHBondContact NE1-O 3.28Å; I171-I209 HydrophobicContact CD1-CG2 3.56Å; I171-I209 HydrophobicContact CG1-CG2 3.74Å; I171-I209 HydrophobicContact CG2-CD1 4.02Å; I171-I209 HydrophobicContact CG2-CG2 4.43Å; L195-I209 HydrophobicContact CB-CD1 4.38Å; L195-I209 HydrophobicContact CD1-CD1 4.31Å; Q205-I209 HydrophobicContact CB-CD1 4.48Å; Q205-I209 WeakPolarHBondContact O-CB 3.49Å; Q205-I209 WeakPolarHBondContact O-CD1 3.47Å; Q205-I209 VanDerWaalsContact O-CG1 3.22Å; Q205-I209 WeakPolarHBondContact O-CG1 3.42Å; Q205-I209 PolarHBondContact O-N 3.2Å; V206-I209 PolarHBondContact O-N 2.81Å; I209-Q211 PolarHBondContact O-N 2.92Å
210	F	95.5	Very high	95	Very high	13 Å²	13	69.2 Å²	69.2	6%	0.057	34%	0.344	C	S	.	.	S	Bend	trans	-89.8	53.3	-170.7	-57.6	-73.6	0	0	0	112.3	L100 I106 W134 I136 L195 V206 E212	L100-F210 HydrophobicContact CD1-CZ 4.48Å; L100-F210 HydrophobicContact CD2-CE2 4.14Å; I106-F210 HydrophobicContact CD1-CB 3.72Å; I106-F210 HydrophobicContact CD1-CG 4.36Å; I106-F210 HydrophobicContact CG1-CB 4.17Å; I106-F210 HydrophobicContact CG1-CD2 4.36Å; I106-F210 HydrophobicContact CG1-CG 4.27Å; I106-F210 HydrophobicContact CG2-CB 4.12Å; I106-F210 HydrophobicContact CG2-CD1 3.94Å; I106-F210 HydrophobicContact CG2-CG 4Å; W134-F210 HydrophobicContact CB-CE1 4.04Å; W134-F210 AromaticContact CD2-CD1 3.66Å; W134-F210 HydrophobicContact CD2-CD1 3.66Å; W134-F210 HydrophobicContact CD2-CE1 4.1Å; W134-F210 AromaticContact CE3-CD1 3.55Å; W134-F210 HydrophobicContact CE3-CD1 3.55Å; W134-F210 HydrophobicContact CE3-CE1 4.18Å; W134-F210 HydrophobicContact CG-CD1 4.06Å; W134-F210 HydrophobicContact CG-CE1 4.02Å; W134-F210 HydrophobicContact CH2-CB 4.35Å; W134-F210 HydrophobicContact CH2-CD1 4.49Å; W134-F210 HydrophobicContact CZ3-CB 4.44Å; W134-F210 HydrophobicContact CZ3-CD1 4.02Å; I136-F210 HydrophobicContact CD1-CE1 4.17Å; I136-F210 HydrophobicContact CD1-CZ 3.82Å; I136-F210 HydrophobicContact CG1-CZ 4.42Å; L195-F210 HydrophobicContact CD2-CE2 4.15Å; L195-F210 HydrophobicContact CD2-CZ 4.49Å; V206-F210 HydrophobicContact CB-CD2 4.22Å; V206-F210 HydrophobicContact CG1-CD2 3.59Å; V206-F210 HydrophobicContact CG1-CE2 4.09Å; V206-F210 VanDerWaalsContact O-CD2 3.23Å; V206-F210 WeakPolarHBondContact O-CD2 3.47Å; V206-F210 PolarHBondContact O-N 3.22Å; F210-E212 PolarHBondContact O-N 2.87Å
211	Q	95.1	Very high	94.8	Very high	87 Å²	87	59.4 Å²	59.4	41%	0.407	31%	0.31	S	S	.	.			trans	-72.1	129.8	179.9	-65.7	-179.1	27.3	0	0	111.5	W134 R208 I209 S213 V214 Y215	W134-Q211 WeakPolarHBondContact CH2-O 3.22Å; R208-Q211 WeakPolarHBondContact O-CG 3.36Å; R208-Q211 PolarHBondContact O-NE2 3.26Å; I209-Q211 PolarHBondContact O-N 2.92Å; Q211-S213 PolarHBondContact O-N 3.09Å; Q211-V214 HydrophobicContact CB-CB 4.45Å; Q211-V214 HydrophobicContact CB-CG2 4.08Å; Q211-V214 WeakPolarHBondContact O-CB 3.24Å; Q211-V214 PolarHBondContact O-N 3.28Å; Q211-V214 VanDerWaalsContact O-N 3.07Å; Q211-Y215 PolarHBondContact O-N 3.19Å; Q211-Y215 VanDerWaalsContact O-N 3.13Å
212	E	94.9	Very high	94.6	Very high	77 Å²	77	60.1 Å²	60.1	36%	0.36	30%	0.304	S	S	.	.	H	α-helix	trans	-60.2	-32.9	179.2	-170.2	62.7	-155.6	0	0	112.2	K80 F210 V214 Y215 K216	K80-E212 WeakPolarHBondContact CE-OE2 3.31Å; K80-E212 IonicContact NZ-OE2 3.07Å; K80-E212 PolarHBondContact NZ-OE2 3.33Å; F210-E212 PolarHBondContact O-N 2.87Å; E212-V214 VanDerWaalsContact C-N 3.34Å; E212-V214 PolarHBondContact O-N 3.29Å; E212-Y215 PolarHBondContact O-N 2.84Å; E212-Y215 WeakPolarHBondContact OE1-CD1 3.43Å; E212-K216 HydrophobicContact CG-CG 4.37Å; E212-K216 WeakPolarHBondContact O-CG 3.29Å; E212-K216 PolarHBondContact O-N 3.01Å; E212-K216 WeakPolarHBondContact OE1-CE 3.49Å; E212-K216 IonicContact OE1-NZ 2.68Å; E212-K216 PolarHBondContact OE1-NZ 3.21Å
213	S	93.7	Very high	94.3	Very high	71 Å²	71	64.4 Å²	64.4	50%	0.497	32%	0.323	S	S	.	.	H	α-helix	trans	-59.8	-41.9	175.3	54.6	0	0	0	0	112.7	Q211 T217	Q211-S213 PolarHBondContact O-N 3.09Å; S213-T217 WeakPolarHBondContact O-CB 3.33Å; S213-T217 PolarHBondContact O-N 3.43Å; S213-T217 VanDerWaalsContact O-N 3.11Å; S213-T217 PolarHBondContact O-OG1 3.48Å
214	V	93.3	Very high	94	Very high	53 Å²	53	67 Å²	67	32%	0.321	33%	0.33	S	S	.	.	H	α-helix	trans	-67.4	-45.8	176.7	175.4	0	0	0	0	109.6	W134 Q211 E212 K216 T217 Q218	W134-V214 HydrophobicContact CZ2-CB 3.91Å; W134-V214 HydrophobicContact CZ2-CG1 3.82Å; Q211-V214 HydrophobicContact CB-CB 4.45Å; Q211-V214 HydrophobicContact CB-CG2 4.08Å; Q211-V214 WeakPolarHBondContact O-CB 3.24Å; Q211-V214 PolarHBondContact O-N 3.28Å; Q211-V214 VanDerWaalsContact O-N 3.07Å; E212-V214 VanDerWaalsContact C-N 3.34Å; E212-V214 PolarHBondContact O-N 3.29Å; V214-K216 PolarHBondContact O-N 3.1Å; V214-T217 PolarHBondContact O-N 2.84Å; V214-Q218 WeakPolarHBondContact O-CG 3.41Å; V214-Q218 PolarHBondContact O-N 2.8Å
215	Y	94.8	Very high	93.5	Very high	14 Å²	14	66 Å²	66	6%	0.055	32%	0.324	C	S	.	.	H	α-helix	trans	-56.2	-50.7	176.1	174.6	-108.6	0	0	0	112.1	F78 K80 A133 W134 Q211 E212 T217 Q218 Q219	F78-Y215 HydrophobicContact CD1-CD2 4.13Å; F78-Y215 AromaticContact CD1-CE2 3.43Å; F78-Y215 HydrophobicContact CD1-CE2 3.43Å; F78-Y215 VanDerWaalsContact CD1-CE2 3.43Å; F78-Y215 AromaticContact CD1-CZ 3.97Å; F78-Y215 AromaticContact CE1-CD2 3.89Å; F78-Y215 HydrophobicContact CE1-CD2 3.89Å; F78-Y215 AromaticContact CE1-CE2 3.67Å; F78-Y215 HydrophobicContact CE1-CE2 3.67Å; F78-Y215 PolarHBondContact O-OH 2.93Å; K80-Y215 HydrophobicContact CB-CD2 4.41Å; K80-Y215 HydrophobicContact CB-CE2 4.38Å; K80-Y215 HydrophobicContact CG-CD2 3.71Å; K80-Y215 HydrophobicContact CG-CE2 3.61Å; K80-Y215 HydrophobicContact CG-CG 4.25Å; A133-Y215 HydrophobicContact CB-CD2 3.76Å; W134-Y215 HydrophobicContact CZ3-CD2 4.36Å; Q211-Y215 PolarHBondContact O-N 3.19Å; Q211-Y215 VanDerWaalsContact O-N 3.13Å; E212-Y215 PolarHBondContact O-N 2.84Å; E212-Y215 WeakPolarHBondContact OE1-CD1 3.43Å; Y215-T217 VanDerWaalsContact C-N 3.3Å; Y215-T217 PolarHBondContact O-N 3.43Å; Y215-Q218 PolarHBondContact O-N 2.75Å; Y215-Q219 VanDerWaalsContact O-CB 3.26Å; Y215-Q219 WeakPolarHBondContact O-CB 3.37Å; Y215-Q219 PolarHBondContact O-N 3.24Å; Y215-Q219 PolarHBondContact OH-NE2 3.05Å; Y215-Q219 VanDerWaalsContact OH-NE2 3.12Å
216	K	94.2	Very high	92.8	Very high	98 Å²	98	67.8 Å²	67.8	43%	0.426	33%	0.329	S	S	.	.	H	α-helix	trans	-61.8	-37.6	179.9	-67.8	-55.8	-174.4	-145.2	0	112.9	E212 V214 T220	E212-K216 HydrophobicContact CG-CG 4.37Å; E212-K216 WeakPolarHBondContact O-CG 3.29Å; E212-K216 PolarHBondContact O-N 3.01Å; E212-K216 WeakPolarHBondContact OE1-CE 3.49Å; E212-K216 IonicContact OE1-NZ 2.68Å; E212-K216 PolarHBondContact OE1-NZ 3.21Å; V214-K216 PolarHBondContact O-N 3.1Å; K216-T220 WeakPolarHBondContact O-CB 3.48Å; K216-T220 PolarHBondContact O-N 2.95Å; K216-T220 PolarHBondContact O-OG1 2.98Å
217	T	93.3	Very high	92.1	Very high	83 Å²	83	71.3 Å²	71.3	51%	0.509	35%	0.348	S	S	.	.	H	α-helix	trans	-64.3	-50.9	177	-57.9	0	0	0	0	110.4	S213 V214 Y215 Q219 T220 I221	S213-T217 WeakPolarHBondContact O-CB 3.33Å; S213-T217 PolarHBondContact O-N 3.43Å; S213-T217 VanDerWaalsContact O-N 3.11Å; S213-T217 PolarHBondContact O-OG1 3.48Å; V214-T217 PolarHBondContact O-N 2.84Å; Y215-T217 VanDerWaalsContact C-N 3.3Å; Y215-T217 PolarHBondContact O-N 3.43Å; T217-Q219 VanDerWaalsContact C-N 3.34Å; T217-Q219 PolarHBondContact O-N 3.26Å; T217-T220 PolarHBondContact O-N 3.07Å; T217-I221 HydrophobicContact CG2-CD1 4.08Å; T217-I221 WeakPolarHBondContact O-CG1 3.11Å; T217-I221 PolarHBondContact O-N 2.99Å; T217-I221 VanDerWaalsContact O-N 3.14Å
218	Q	93.4	Very high	91.2	Very high	7 Å²	7	70.3 Å²	70.3	3%	0.033	34%	0.344	C	S	.	.	H	α-helix	trans	-64	-39.7	178.6	-68.3	-162.6	43.4	0	0	112.4	F78 A133 H165 V214 Y215 T220 I221 W222	F78-Q218 HydrophobicContact CE1-CB 4.11Å; F78-Q218 HydrophobicContact CZ-CB 3.85Å; A133-Q218 VanDerWaalsContact CA-OE1 3.3Å; A133-Q218 HydrophobicContact CB-CB 4.4Å; A133-Q218 PolarHBondContact O-NE2 3.16Å; A133-Q218 PolarHBondContact O-OE1 3.27Å; A133-Q218 VanDerWaalsContact O-OE1 3.11Å; H165-Q218 VanDerWaalsContact O-CD 3.29Å; H165-Q218 VanDerWaalsContact O-CG 3.31Å; H165-Q218 WeakPolarHBondContact O-CG 3.35Å; V214-Q218 WeakPolarHBondContact O-CG 3.41Å; V214-Q218 PolarHBondContact O-N 2.8Å; Y215-Q218 PolarHBondContact O-N 2.75Å; Q218-T220 VanDerWaalsContact C-N 3.33Å; Q218-T220 PolarHBondContact O-N 3.17Å; Q218-I221 PolarHBondContact O-N 2.72Å; Q218-W222 WeakPolarHBondContact O-CB 3.42Å; Q218-W222 PolarHBondContact O-N 3.07Å
219	Q	93.7	Very high	90.3	Very high	33 Å²	33	64.6 Å²	64.6	15%	0.154	33%	0.33	C	S	.	.	H	α-helix	trans	-61.7	-41.5	177.3	-174.8	174.8	51.1	0	0	111.8	F78 Y215 T217 W222 K223	F78-Q219 HydrophobicContact CB-CG 4.19Å; F78-Q219 HydrophobicContact CD1-CB 3.5Å; F78-Q219 VanDerWaalsContact CD1-CB 3.5Å; F78-Q219 HydrophobicContact CD1-CG 3.71Å; F78-Q219 HydrophobicContact CE1-CB 3.77Å; F78-Q219 HydrophobicContact CE1-CG 4.47Å; F78-Q219 HydrophobicContact CG-CB 4.33Å; F78-Q219 HydrophobicContact CG-CG 4.18Å; Y215-Q219 VanDerWaalsContact O-CB 3.26Å; Y215-Q219 WeakPolarHBondContact O-CB 3.37Å; Y215-Q219 PolarHBondContact O-N 3.24Å; Y215-Q219 PolarHBondContact OH-NE2 3.05Å; Y215-Q219 VanDerWaalsContact OH-NE2 3.12Å; T217-Q219 VanDerWaalsContact C-N 3.34Å; T217-Q219 PolarHBondContact O-N 3.26Å; Q219-W222 PolarHBondContact O-N 2.91Å; Q219-K223 HydrophobicContact CG-CD 4.42Å; Q219-K223 WeakPolarHBondContact O-CB 3.31Å; Q219-K223 VanDerWaalsContact O-CG 3.31Å; Q219-K223 WeakPolarHBondContact O-CG 3.37Å; Q219-K223 PolarHBondContact O-N 3.1Å
220	T	93.3	Very high	89.1	Confident	73 Å²	73	67.5 Å²	67.5	45%	0.448	34%	0.343	S	S	.	.	H	α-helix	trans	-62.1	-48.7	176.6	-56.6	0	0	0	0	110.7	K216 T217 Q218 W222 K223 E224	K216-T220 WeakPolarHBondContact O-CB 3.48Å; K216-T220 PolarHBondContact O-N 2.95Å; K216-T220 PolarHBondContact O-OG1 2.98Å; T217-T220 PolarHBondContact O-N 3.07Å; Q218-T220 VanDerWaalsContact C-N 3.33Å; Q218-T220 PolarHBondContact O-N 3.17Å; T220-W222 VanDerWaalsContact C-N 3.32Å; T220-W222 PolarHBondContact O-N 3.18Å; T220-K223 PolarHBondContact O-N 2.88Å; T220-E224 WeakPolarHBondContact O-CG 2.88Å; T220-E224 PolarHBondContact O-N 3.02Å
221	I	91.3	Very high	87.9	Confident	46 Å²	46	75.9 Å²	75.9	24%	0.236	37%	0.374	C	S	.	.	H	α-helix	trans	-62.8	-40.2	179.5	-65.5	168.6	0	0	0	111.4	H165 T217 Q218 E224 T225	H165-I221 HydrophobicContact CB-CD1 3.46Å; H165-I221 VanDerWaalsContact CB-CD1 3.46Å; H165-I221 HydrophobicContact CB-CG2 4.18Å; T217-I221 HydrophobicContact CG2-CD1 4.08Å; T217-I221 WeakPolarHBondContact O-CG1 3.11Å; T217-I221 PolarHBondContact O-N 2.99Å; T217-I221 VanDerWaalsContact O-N 3.14Å; Q218-I221 PolarHBondContact O-N 2.72Å; I221-E224 PolarHBondContact O-N 3.25Å; I221-T225 WeakPolarHBondContact O-CB 3.43Å; I221-T225 PolarHBondContact O-N 2.85Å; I221-T225 PolarHBondContact O-OG1 3.03Å
222	W	90.8	Very high	86.3	Confident	40 Å²	40	78.2 Å²	78.2	15%	0.152	39%	0.385	C	S	.	.	H	α-helix	trans	-62.3	-46.7	176.1	177.1	85.6	0	0	0	111.5	E76 F78 Q218 Q219 T220 E224 T225 R226	E76-W222 HydrophobicContact CB-CH2 4.25Å; E76-W222 HydrophobicContact CB-CZ2 4.43Å; E76-W222 HydrophobicContact CG-CZ2 4.26Å; E76-W222 WeakPolarHBondContact O-CH2 3.4Å; F78-W222 HydrophobicContact CB-CD2 4.13Å; F78-W222 HydrophobicContact CB-CE3 3.73Å; F78-W222 HydrophobicContact CB-CH2 4.47Å; F78-W222 HydrophobicContact CB-CZ3 3.92Å; F78-W222 HydrophobicContact CD2-CB 3.83Å; F78-W222 AromaticContact CD2-CD1 3.79Å; F78-W222 AromaticContact CD2-CD2 3.53Å; F78-W222 HydrophobicContact CD2-CD2 3.53Å; F78-W222 AromaticContact CD2-CE3 3.98Å; F78-W222 HydrophobicContact CD2-CE3 3.98Å; F78-W222 AromaticContact CD2-CG 3.43Å; F78-W222 HydrophobicContact CD2-CG 3.43Å; F78-W222 VanDerWaalsContact CD2-CG 3.43Å; F78-W222 HydrophobicContact CE2-CB 3.78Å; F78-W222 AromaticContact CE2-CD1 3.93Å; F78-W222 HydrophobicContact CE2-CD2 4.31Å; F78-W222 AromaticContact CE2-CG 3.73Å; F78-W222 HydrophobicContact CE2-CG 3.73Å; F78-W222 HydrophobicContact CG-CD2 4.12Å; F78-W222 HydrophobicContact CG-CE3 4.09Å; F78-W222 HydrophobicContact CG-CG 4.32Å; F78-W222 HydrophobicContact CZ-CB 4.46Å; Q218-W222 WeakPolarHBondContact O-CB 3.42Å; Q218-W222 PolarHBondContact O-N 3.07Å; Q219-W222 PolarHBondContact O-N 2.91Å; T220-W222 VanDerWaalsContact C-N 3.32Å; T220-W222 PolarHBondContact O-N 3.18Å; W222-E224 PolarHBondContact O-N 3.45Å; W222-T225 PolarHBondContact O-N 3.3Å; W222-R226 WeakPolarHBondContact O-CB 3.24Å; W222-R226 PolarHBondContact O-N 2.72Å
223	K	90.8	Very high	84.4	Confident	104 Å²	104	82.8 Å²	82.8	45%	0.452	40%	0.404	S	S	.	.	H	α-helix	trans	-60.8	-44.5	176	-73.6	179.4	180	-176	0	112.1	Q219 T220 R226 N227	Q219-K223 HydrophobicContact CG-CD 4.42Å; Q219-K223 WeakPolarHBondContact O-CB 3.31Å; Q219-K223 VanDerWaalsContact O-CG 3.31Å; Q219-K223 WeakPolarHBondContact O-CG 3.37Å; Q219-K223 PolarHBondContact O-N 3.1Å; T220-K223 PolarHBondContact O-N 2.88Å; K223-R226 PolarHBondContact O-N 2.68Å; K223-N227 WeakPolarHBondContact O-CB 3.37Å; K223-N227 PolarHBondContact O-N 3.18Å; K223-N227 PolarHBondContact O-ND2 3.3Å
224	E	89.6	Confident	82.7	Confident	113 Å²	113	86.5 Å²	86.5	53%	0.528	42%	0.417	S	S	.	.	H	α-helix	trans	-62.8	-46.7	178.2	-74.2	176.4	174.7	0	0	112.1	T220 I221 W222 R226 N227 M228	T220-E224 WeakPolarHBondContact O-CG 2.88Å; T220-E224 PolarHBondContact O-N 3.02Å; I221-E224 PolarHBondContact O-N 3.25Å; W222-E224 PolarHBondContact O-N 3.45Å; E224-R226 VanDerWaalsContact C-N 3.33Å; E224-R226 PolarHBondContact O-N 2.75Å; E224-N227 PolarHBondContact O-N 3.06Å; E224-M228 WeakPolarHBondContact O-CG 3.2Å; E224-M228 PolarHBondContact O-N 3.11Å
225	T	86.6	Confident	80.4	Confident	73 Å²	73	90.7 Å²	90.7	45%	0.448	46%	0.457	S	S	.	.	H	α-helix	trans	-59.6	-45.6	178.8	-56.2	0	0	0	0	110.8	I221 W222 M228 V229	I221-T225 WeakPolarHBondContact O-CB 3.43Å; I221-T225 PolarHBondContact O-N 2.85Å; I221-T225 PolarHBondContact O-OG1 3.03Å; W222-T225 PolarHBondContact O-N 3.3Å; T225-M228 PolarHBondContact O-N 3.21Å; T225-V229 WeakPolarHBondContact O-CG2 3.33Å; T225-V229 PolarHBondContact O-N 3.08Å
226	R	82.9	Confident	79.7	Confident	81 Å²	81	94.5 Å²	94.5	31%	0.306	48%	0.477	S	S	.	.	H	α-helix	trans	-63.5	-44	178.6	-169.1	-177.6	-177.8	95.3	-4.6	112.3	E76 W222 K223 E224 M228 V229 Q230	E76-R226 IonicContact OE1-CZ 2.69Å; E76-R226 IonicContact OE1-NH1 2.66Å; E76-R226 PolarHBondContact OE1-NH1 2.69Å; E76-R226 IonicContact OE2-CZ 2.7Å; E76-R226 IonicContact OE2-NH1 3.79Å; E76-R226 PolarHBondContact OE2-NH1 3.2Å; E76-R226 IonicContact OE2-NH2 3.09Å; E76-R226 PolarHBondContact OE2-NH2 3.32Å; W222-R226 WeakPolarHBondContact O-CB 3.24Å; W222-R226 PolarHBondContact O-N 2.72Å; K223-R226 PolarHBondContact O-N 2.68Å; E224-R226 VanDerWaalsContact C-N 3.33Å; E224-R226 PolarHBondContact O-N 2.75Å; R226-M228 VanDerWaalsContact C-N 3.29Å; R226-M228 PolarHBondContact O-N 3.16Å; R226-V229 PolarHBondContact O-N 3.24Å; R226-Q230 WeakPolarHBondContact O-CG 3.25Å; R226-Q230 PolarHBondContact O-N 3.12Å
227	N	80.8	Confident	78.9	Confident	76 Å²	76	94.3 Å²	94.3	41%	0.406	48%	0.479	S	S	.	.	H	α-helix	trans	-60.9	-37.6	176.7	-73.7	-23.9	0	0	0	112.1	K223 E224 R231	K223-N227 WeakPolarHBondContact O-CB 3.37Å; K223-N227 PolarHBondContact O-N 3.18Å; K223-N227 PolarHBondContact O-ND2 3.3Å; E224-N227 PolarHBondContact O-N 3.06Å; N227-R231 VanDerWaalsContact O-CG 3.24Å; N227-R231 WeakPolarHBondContact O-CG 3.26Å; N227-R231 PolarHBondContact O-N 3.46Å
228	M	77.9	Confident	78.1	Confident	117 Å²	117	94.9 Å²	94.9	58%	0.576	48%	0.478	S	S	*	.	H	α-helix	trans	-67.5	-45	175.9	-73.2	-177.5	64.4	0	0	112.2	E224 T225 R226 R231 Q232	E224-M228 WeakPolarHBondContact O-CG 3.2Å; E224-M228 PolarHBondContact O-N 3.11Å; T225-M228 PolarHBondContact O-N 3.21Å; R226-M228 VanDerWaalsContact C-N 3.29Å; R226-M228 PolarHBondContact O-N 3.16Å; M228-R231 PolarHBondContact O-N 3.46Å; M228-Q232 WeakPolarHBondContact O-CG 3.45Å; M228-Q232 PolarHBondContact O-N 2.78Å; M228-Q232 VanDerWaalsContact O-N 3.11Å
229	V	75.2	Confident	77.2	Confident	65 Å²	65	100.1 Å²	100.1	39%	0.394	50%	0.504	S	S	.	.	H	α-helix	trans	-62	-48.3	178.6	173.3	0	0	0	0	110.5	T225 R226 R231 Q232 F233	T225-V229 WeakPolarHBondContact O-CG2 3.33Å; T225-V229 PolarHBondContact O-N 3.08Å; R226-V229 PolarHBondContact O-N 3.24Å; V229-R231 VanDerWaalsContact C-N 3.31Å; V229-R231 PolarHBondContact O-N 3.49Å; V229-Q232 PolarHBondContact O-N 3.05Å; V229-F233 HydrophobicContact CG1-CD2 3.71Å; V229-F233 HydrophobicContact CG1-CE2 3.66Å; V229-F233 VanDerWaalsContact O-CD2 3.31Å; V229-F233 WeakPolarHBondContact O-CD2 3.31Å; V229-F233 PolarHBondContact O-N 3.09Å; V229-F233 VanDerWaalsContact O-N 3.13Å
230	Q	71.1	Confident	76.2	Confident	93 Å²	93	104.3 Å²	104.3	44%	0.435	53%	0.526	S	S	.	.	H	α-helix	trans	-58.3	-40.9	177.1	-75.5	178.8	-23.1	0	0	112.5	R226 Q232 F233 I234	R226-Q230 WeakPolarHBondContact O-CG 3.25Å; R226-Q230 PolarHBondContact O-N 3.12Å; Q230-Q232 VanDerWaalsContact C-N 3.3Å; Q230-Q232 PolarHBondContact O-N 3.29Å; Q230-F233 PolarHBondContact O-N 3.21Å; Q230-I234 WeakPolarHBondContact O-CD1 3.44Å; Q230-I234 VanDerWaalsContact O-CG1 3.29Å; Q230-I234 WeakPolarHBondContact O-CG1 3.23Å; Q230-I234 PolarHBondContact O-N 3.37Å
231	R	69.1	Low	75	Confident	190 Å²	190	106.4 Å²	106.4	72%	0.717	53%	0.531	S	S	*	.	H	α-helix	trans	-66.1	-29.9	176.6	-73.5	176.6	-164.8	-168.2	5.4	113.5	N227 M228 V229	N227-R231 VanDerWaalsContact O-CG 3.24Å; N227-R231 WeakPolarHBondContact O-CG 3.26Å; N227-R231 PolarHBondContact O-N 3.46Å; M228-R231 PolarHBondContact O-N 3.46Å; V229-R231 VanDerWaalsContact C-N 3.31Å; V229-R231 PolarHBondContact O-N 3.49Å
232	Q	61.1	Low	73.9	Confident	135 Å²	135	110.7 Å²	110.7	63%	0.631	55%	0.552	S	S	*	*	H	α-helix	trans	-78.3	-25.4	177.6	-73.2	176.6	-4.7	0	0	113	M228 V229 Q230	M228-Q232 WeakPolarHBondContact O-CG 3.45Å; M228-Q232 PolarHBondContact O-N 2.78Å; M228-Q232 VanDerWaalsContact O-N 3.11Å; V229-Q232 PolarHBondContact O-N 3.05Å; Q230-Q232 VanDerWaalsContact C-N 3.3Å; Q230-Q232 PolarHBondContact O-N 3.29Å
233	F	56.6	Low	72.6	Confident	173 Å²	173	116.2 Å²	116.2	76%	0.759	58%	0.583	S	S	*	*	H	α-helix	trans	-85.4	-16.9	176.5	-83.8	-76.8	0	0	0	113.9	V229 Q230	V229-F233 HydrophobicContact CG1-CD2 3.71Å; V229-F233 HydrophobicContact CG1-CE2 3.66Å; V229-F233 VanDerWaalsContact O-CD2 3.31Å; V229-F233 WeakPolarHBondContact O-CD2 3.31Å; V229-F233 PolarHBondContact O-N 3.09Å; V229-F233 VanDerWaalsContact O-N 3.13Å; Q230-F233 PolarHBondContact O-N 3.21Å
234	I	56.4	Low	71.1	Confident	150 Å²	150	117.2 Å²	117.2	77%	0.769	59%	0.594	S	S	*	*			trans	-93	-14.1	178.7	-64.8	168	0	0	0	112.2	Q230	Q230-I234 WeakPolarHBondContact O-CD1 3.44Å; Q230-I234 VanDerWaalsContact O-CG1 3.29Å; Q230-I234 WeakPolarHBondContact O-CG1 3.23Å; Q230-I234 PolarHBondContact O-N 3.37Å
235	A	45.6	Very low	69.4	Low	140 Å²	140	117.5 Å²	117.5	100%	1.157	60%	0.6	S	S	*	*			trans	-95.2	0	179.4	0	0	0	0	0	112.2

Retrieved 235 of 235 residues in 160.7 ms (Link to these results)

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