A0A096MWM3_PAPAN Loading...

Transmembrane protein 39A

AlphaFold DB , UniProt , Accession A0A096MWM3, Species PAPAN (Papio anubis, Olive baboon), Gene TMEM39A, Length 488 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	42.6	Very low	37.1	Very low	244 Å²	244	163.5 Å²	163.5	100%	1.202	89%	0.894	S	S	*	*				0	106.6	0	-76.9	-177.2	151	0	0	109.8
2	P	40.5	Very low	36.4	Very low	136 Å²	136	166.3 Å²	166.3	88%	0.883	90%	0.897	S	S	*	*			trans	-111.2	147.7	152.2	33	-19.7	0	0	0	107.8
3	G	34	Very low	35.8	Very low	74 Å²	74	166.1 Å²	166.1	76%	0.763	89%	0.894	S	S	*	*			cis	137	93.4	38.3	0	0	0	0	0	104.9
4	G	40.6	Very low	35.2	Very low	85 Å²	85	162.6 Å²	162.6	88%	0.876	89%	0.889	S	S	*	*			trans	-75.8	132.5	-179.2	0	0	0	0	0	111.9
5	R	38.1	Very low	34.8	Very low	252 Å²	252	168.1 Å²	168.1	95%	0.951	89%	0.891	S	S	*	*			trans	-134.3	120.2	165.4	-100.3	-176.6	173.5	-178	-1.4	109.6
6	R	43.5	Very low	34.3	Very low	258 Å²	258	164.5 Å²	164.5	97%	0.974	88%	0.884	S	S	*	*			trans	-76.3	143.8	163.4	-77.4	178.6	175.2	171.8	-1.6	109.4
7	G	36.4	Very low	34	Very low	70 Å²	70	160.8 Å²	160.8	72%	0.722	88%	0.881	S	S	*	*			trans	-142	157.3	164.8	0	0	0	0	0	110
8	P	37.8	Very low	33.7	Very low	126 Å²	126	160.9 Å²	160.9	82%	0.818	88%	0.88	S	S	*	*			trans	-93.5	160.8	-143.9	35.2	-34.8	0	0	0	115.8
9	S	34	Very low	33.5	Very low	124 Å²	124	158.6 Å²	158.6	87%	0.867	87%	0.873	S	S	*	*			trans	-56.7	128.5	171.8	37.3	0	0	0	0	112.6
10	R	31.2	Very low	33.2	Very low	247 Å²	247	156.2 Å²	156.2	93%	0.932	87%	0.868	S	S	*	*			trans	-112.8	124.8	169.6	-150.7	178.5	-172	-153.8	1.9	110
11	Q	29.3	Very low	33.2	Very low	182 Å²	182	157.1 Å²	157.1	85%	0.85	87%	0.87	S	S	*	*	P	Polyproline II helix	trans	-50.4	131.3	177.2	-65.3	159.3	-30.2	0	0	112
12	Q	28.3	Very low	32.6	Very low	197 Å²	197	154.2 Å²	154.2	92%	0.921	85%	0.854	S	S	*	*	P	Polyproline II helix	trans	-100.6	122.5	157.6	-98.9	-173.7	-37.2	0	0	108.9
13	L	29.5	Very low	32.2	Very low	164 Å²	164	154 Å²	154	86%	0.859	85%	0.85	S	S	*	*	P	Polyproline II helix	trans	-57.1	138.7	178.4	-78	95.8	0	0	0	111.8
14	S	27.2	Very low	31.9	Very low	118 Å²	118	158.7 Å²	158.7	83%	0.825	86%	0.857	S	S	*	*	P	Polyproline II helix	trans	-47	128.5	161.6	35.8	0	0	0	0	112.3
15	R	28.4	Very low	31.4	Very low	244 Å²	244	161.3 Å²	161.3	92%	0.921	86%	0.856	S	S	*	*			trans	-116.8	113.9	152	-103.4	-174.7	178.5	-164.9	0	109	A17	R15-A17 PolarHBondContact O-N 3.35Å
16	S	27.9	Very low	30.9	Very low	111 Å²	111	153 Å²	153	78%	0.776	85%	0.849	S	S	*	*			trans	-25.1	115.5	166.1	49.8	0	0	0	0	115.2
17	A	28.3	Very low	30.2	Very low	102 Å²	102	144.8 Å²	144.8	84%	0.843	84%	0.844	S	S	*	*	P	Polyproline II helix	trans	-80.5	122.2	157	0	0	0	0	0	108.5	R15	R15-A17 PolarHBondContact O-N 3.35Å
18	L	29.2	Very low	29.7	Very low	163 Å²	163	144.8 Å²	144.8	85%	0.853	84%	0.844	S	S	*	*	P	Polyproline II helix	trans	-84.6	148.5	161.5	-84.8	158.1	0	0	0	108.8
19	P	30.1	Very low	29.2	Very low	117 Å²	117	145.7 Å²	145.7	76%	0.76	85%	0.852	S	S	*	*	P	Polyproline II helix	trans	-84.7	143.1	-162.5	18.5	-6.5	0	0	0	113
20	S	27	Very low	28.9	Very low	109 Å²	109	143.5 Å²	143.5	76%	0.762	85%	0.848	S	S	*	*	P	Polyproline II helix	trans	-75	122.3	166.7	53.9	0	0	0	0	110.3	Q22	S20-Q22 PolarHBondContact O-N 3.47Å
21	L	32.5	Very low	28.9	Very low	176 Å²	176	140.3 Å²	140.3	92%	0.921	85%	0.85	S	S	*	*	S	Bend	trans	-61.5	93.6	167.2	-99.9	155	0	0	0	110.2
22	Q	31	Very low	28.9	Very low	184 Å²	184	135.4 Å²	135.4	86%	0.86	85%	0.848	S	S	*	*			trans	-161.8	72.4	158.6	-107.5	169.8	24.8	0	0	108.4	S20	S20-Q22 PolarHBondContact O-N 3.47Å
23	T	33.1	Very low	28.9	Very low	131 Å²	131	132.9 Å²	132.9	80%	0.804	85%	0.846	S	S	*	*			trans	-152.7	82.8	164.6	-18.3	0	0	0	0	109
24	L	27.4	Very low	28.9	Very low	172 Å²	172	128.4 Å²	128.4	90%	0.901	84%	0.839	S	S	*	*			trans	-170.9	101.6	157.4	-121.1	99.4	0	0	0	102.1
25	V	30.1	Very low	29	Very low	141 Å²	141	130.6 Å²	130.6	86%	0.855	84%	0.841	S	S	*	*				-160.7	139.7	78.7	165.9	0	0	0	0	107.9
26	G	27	Very low	29.1	Very low	78 Å²	78	129.7 Å²	129.7	80%	0.804	84%	0.837	S	S	*	*			trans	-88.4	-174.7	-173	0	0	0	0	0	116.8
27	G	27.8	Very low	29.3	Very low	84 Å²	84	131.1 Å²	131.1	87%	0.866	84%	0.837	S	S	*	*			trans	124.7	111.7	-179.4	0	0	0	0	0	108.2
28	G	25.9	Very low	29.4	Very low	70 Å²	70	138 Å²	138	72%	0.722	84%	0.841	S	S	*	*			cis	129	109.4	23.7	0	0	0	0	0	107.4
29	C	28.1	Very low	29.5	Very low	146 Å²	146	137.8 Å²	137.8	99%	0.986	84%	0.841	S	S	*	*			trans	73.7	133.2	162.8	-62.9	0	0	0	0	120.8
30	G	28.1	Very low	29.4	Very low	77 Å²	77	135.5 Å²	135.5	79%	0.794	84%	0.838	S	S	*	*			trans	139.4	83	142.8	0	0	0	0	0	117.3
31	N	30.8	Very low	30	Very low	181 Å²	181	136.9 Å²	136.9	97%	0.968	85%	0.848	S	S	*	*			trans	-64.5	140.1	158.2	-92.6	-10.4	0	0	0	110.3
32	G	28.8	Very low	30	Very low	78 Å²	78	132.7 Å²	132.7	80%	0.804	84%	0.838	S	S	*	*			trans	-171.6	104	172.1	0	0	0	0	0	113.2
33	T	29	Very low	30.2	Very low	145 Å²	145	132.3 Å²	132.3	89%	0.89	84%	0.841	S	S	*	*			trans	-68.6	137.2	173.3	42.6	0	0	0	0	113.4
34	G	29.1	Very low	30	Very low	69 Å²	69	129.2 Å²	129.2	71%	0.711	83%	0.834	S	S	*	*			trans	62.3	124.2	140.8	0	0	0	0	0	120.7
35	L	29.9	Very low	30.3	Very low	164 Å²	164	128.3 Å²	128.3	86%	0.859	83%	0.829	S	S	*	*				167.4	121.4	121.6	-91.4	153.6	0	0	0	112.7
36	R	29.5	Very low	30.4	Very low	225 Å²	225	127.1 Å²	127.1	85%	0.849	83%	0.825	S	S	*	*				48.5	103.1	126.3	-161.5	171.8	-179.8	175.8	-0.7	119.6
37	N	32.3	Very low	30.6	Very low	142 Å²	142	129 Å²	129	76%	0.759	82%	0.821	S	S	*	*				30.7	116.4	129.4	-150.4	17.7	0	0	0	119
38	R	30	Very low	31	Very low	245 Å²	245	129.9 Å²	129.9	93%	0.925	81%	0.811	S	S	*	*			trans	-149.5	117.6	152.1	-142.1	172.2	172.9	172.8	-3.4	110.8	G40	R38-G40 PolarHBondContact O-N 3.48Å
39	N	32.3	Very low	31.5	Very low	160 Å²	160	131.1 Å²	131.1	86%	0.856	81%	0.806	S	S	*	*			trans	-50.3	122.7	167.9	-77.2	-17.1	0	0	0	110.4
40	G	28.5	Very low	32.1	Very low	68 Å²	68	131.2 Å²	131.2	70%	0.701	80%	0.795	S	S	*	*			trans	-144.2	105.5	168.7	0	0	0	0	0	108	R38 A42	R38-G40 PolarHBondContact O-N 3.48Å; G40-A42 PolarHBondContact O-N 3.29Å
41	S	39.8	Very low	32.8	Very low	138 Å²	138	131.6 Å²	131.6	97%	0.965	78%	0.783	S	S	*	*			trans	-63.1	94.1	168	42.6	0	0	0	0	109.2
42	A	30.7	Very low	33.1	Very low	88 Å²	88	127 Å²	127	73%	0.727	77%	0.77	S	S	*	*			trans	-114.8	120.6	165.7	0	0	0	0	0	107.6	G40 G44	G40-A42 PolarHBondContact O-N 3.29Å; A42-G44 PolarHBondContact O-N 3.23Å
43	I	36.9	Very low	33.6	Very low	177 Å²	177	130.4 Å²	130.4	91%	0.908	77%	0.769	S	S	*	*			trans	-58.7	100.2	169.9	-68.1	161.7	0	0	0	106.7	L45	I43-L45 PolarHBondContact O-N 2.98Å
44	G	27.9	Very low	34.6	Very low	65 Å²	65	129.8 Å²	129.8	67%	0.67	76%	0.758	S	S	*	*			trans	-73.8	108.2	174.1	0	0	0	0	0	108.9	A42	A42-G44 PolarHBondContact O-N 3.23Å
45	L	34.7	Very low	35.5	Very low	153 Å²	153	132.1 Å²	132.1	80%	0.801	76%	0.759	S	S	*	*	P	Polyproline II helix	trans	-48.4	134.8	151.9	-79.1	156	0	0	0	107.8	I43 V47	I43-L45 PolarHBondContact O-N 2.98Å; L45-V47 PolarHBondContact O-N 3.44Å
46	P	31.8	Very low	36.8	Very low	116 Å²	116	125.7 Å²	125.7	75%	0.753	73%	0.727	S	S	*	*	P	Polyproline II helix	trans	-60.8	117.4	175.5	24.3	-29.7	0	0	0	107.6	P48	P46-P48 WeakPolarHBondContact O-CD 3.38Å; P46-P48 VanDerWaalsContact O-N 3.09Å
47	V	31.7	Very low	38.2	Very low	119 Å²	119	117.6 Å²	117.6	72%	0.721	71%	0.714	S	S	*	*	P	Polyproline II helix	trans	-52.6	117.6	168.2	174.6	0	0	0	0	106.3	L45	L45-V47 PolarHBondContact O-N 3.44Å
48	P	35.5	Very low	39.5	Very low	102 Å²	102	115.4 Å²	115.4	66%	0.662	71%	0.708	S	S	*	*	P	Polyproline II helix	trans	-61	137.2	175.7	25.3	-30.9	0	0	0	107.2	P46 I50	P46-P48 WeakPolarHBondContact O-CD 3.38Å; P46-P48 VanDerWaalsContact O-N 3.09Å; P48-I50 PolarHBondContact O-N 3.21Å; P48-I50 VanDerWaalsContact O-N 3.09Å
49	P	36.9	Very low	41.1	Very low	95 Å²	95	105.1 Å²	105.1	62%	0.617	67%	0.672	S	S	*	*	P	Polyproline II helix	trans	-58	124.6	179	24.7	-32.2	0	0	0	108.4	T51 A52	P49-T51 PolarHBondContact O-N 3.18Å; P49-A52 PolarHBondContact O-N 3.38Å
50	I	40	Very low	42.3	Very low	148 Å²	148	106.1 Å²	106.1	76%	0.759	66%	0.664	S	S	*	*	G	3₁₀ helix	trans	-58.2	-3.7	178.5	-67	164.7	0	0	0	112.2	P48 A52 L53	P48-I50 PolarHBondContact O-N 3.21Å; P48-I50 VanDerWaalsContact O-N 3.09Å; I50-A52 PolarHBondContact O-N 3.32Å; I50-A52 VanDerWaalsContact O-N 3.11Å; I50-L53 PolarHBondContact O-N 3.39Å
51	T	42.8	Very low	44.3	Very low	86 Å²	86	106 Å²	106	53%	0.528	65%	0.645	S	S	.	*	G	3₁₀ helix	trans	-60.8	-12.3	171.4	-24.1	0	0	0	0	114.5	P49 L53	P49-T51 PolarHBondContact O-N 3.18Å; T51-L53 VanDerWaalsContact C-N 3.26Å; T51-L53 PolarHBondContact O-N 3.35Å
52	A	37.5	Very low	45.5	Very low	85 Å²	85	101.3 Å²	101.3	70%	0.702	61%	0.611	S	S	*	*	G	3₁₀ helix	trans	-73.3	-6.6	177.6	0	0	0	0	0	115.1	P49 I50	P49-A52 PolarHBondContact O-N 3.38Å; I50-A52 PolarHBondContact O-N 3.32Å; I50-A52 VanDerWaalsContact O-N 3.11Å
53	L	39.9	Very low	47	Very low	149 Å²	149	106.3 Å²	106.3	78%	0.78	62%	0.62	S	S	*	*	G	3₁₀ helix	trans	-104.2	1.6	-166	-124.4	138	0	0	0	116.5	I50 T51	I50-L53 PolarHBondContact O-N 3.39Å; T51-L53 VanDerWaalsContact C-N 3.26Å; T51-L53 PolarHBondContact O-N 3.35Å
54	I	48.2	Very low	48.4	Very low	131 Å²	131	99.6 Å²	99.6	67%	0.672	59%	0.585	S	S	*	*			trans	-115.8	73.6	165.4	-48.7	177.1	0	0	0	107.3	P56	I54-P56 WeakPolarHBondContact O-CD 3.18Å; I54-P56 VanDerWaalsContact O-N 3.16Å
55	T	48.6	Very low	50.1	Low	119 Å²	119	100.1 Å²	100.1	73%	0.73	58%	0.577	S	S	*	*			trans	-59.3	114.4	160.5	33.6	0	0	0	0	106.9	G57	T55-G57 PolarHBondContact O-N 3.35Å
56	P	58.3	Low	51.3	Low	28 Å²	28	99 Å²	99	18%	0.182	57%	0.572	C	S	.	*	P	Polyproline II helix	trans	-56.4	133.3	174	21	-29	0	0	0	108.1	I54 I377 Y397	I54-P56 WeakPolarHBondContact O-CD 3.18Å; I54-P56 VanDerWaalsContact O-N 3.16Å; P56-I377 HydrophobicContact CG-CG2 3.82Å; P56-Y397 HydrophobicContact CB-CD1 4.41Å; P56-Y397 HydrophobicContact CB-CD2 4.42Å; P56-Y397 HydrophobicContact CB-CE1 4.02Å; P56-Y397 HydrophobicContact CB-CE2 4.07Å; P56-Y397 HydrophobicContact CG-CD1 3.99Å; P56-Y397 HydrophobicContact CG-CE1 3.59Å; P56-Y397 PolarHBondContact O-OH 3.28Å
57	G	57.4	Low	52.7	Low	56 Å²	56	94.2 Å²	94.2	58%	0.577	54%	0.54	S	S	*	.	P	Polyproline II helix	trans	-62.5	143	-179.8	0	0	0	0	0	110.8	T55 V59 Y397	T55-G57 PolarHBondContact O-N 3.35Å; G57-V59 PolarHBondContact O-N 3.32Å; G57-Y397 WeakPolarHBondContact O-CE2 3.43Å; G57-Y397 PolarHBondContact O-OH 3.21Å
58	P	60.7	Low	54	Low	96 Å²	96	92.8 Å²	92.8	62%	0.623	53%	0.533	S	S	*	.	P	Polyproline II helix	trans	-50.5	134.2	-169.1	19.9	-32.7	0	0	0	112.8	R60 Y397	P58-R60 PolarHBondContact O-N 2.75Å; P58-Y397 WeakPolarHBondContact CA-OH 3.48Å
59	V	62.4	Low	55.4	Low	29 Å²	29	92.5 Å²	92.5	18%	0.176	53%	0.529	C	S	.	.			trans	-59	110.7	169.6	-177.5	0	0	0	0	108.1	G57 A351 H352 Y397	G57-V59 PolarHBondContact O-N 3.32Å; V59-A351 HydrophobicContact CG1-CB 4.09Å; V59-H352 VanDerWaalsContact CB-CE1 3.44Å; V59-H352 WeakPolarHBondContact CB-CE1 3.36Å; V59-H352 VanDerWaalsContact CG2-ND1 3.32Å; V59-H352 WeakPolarHBondContact CG2-ND1 3.32Å; V59-Y397 HydrophobicContact CB-CD2 4.48Å; V59-Y397 HydrophobicContact CB-CE2 4.25Å; V59-Y397 HydrophobicContact CG2-CD2 3.11Å; V59-Y397 HydrophobicContact CG2-CE2 3.19Å; V59-Y397 HydrophobicContact CG2-CG 3.83Å
60	R	59.2	Low	56.7	Low	180 Å²	180	89.6 Å²	89.6	68%	0.679	51%	0.509	S	S	*	.	P	Polyproline II helix	trans	-82.8	123.6	177.8	-66.3	-175.8	-177.9	165.6	1.4	109.5	P58	P58-R60 PolarHBondContact O-N 2.75Å
61	H	70.4	Confident	58.4	Low	66 Å²	66	84.7 Å²	84.7	31%	0.306	49%	0.494	S	S	.	.	P	Polyproline II helix	trans	-92.6	134.3	176.7	-62.3	-51.5	0	0	0	110.3	H261 C263 K348 H352	H61-H261 AromaticContact NE2-CE1 3.83Å; H61-C263 PolarHBondContact NE2-SG 2.86Å; H61-C263 VanDerWaalsContact NE2-SG 3.37Å; H61-K348 HydrophobicContact CB-CD 4.4Å; H61-K348 WeakPolarHBondContact ND1-CG 3.22Å; H61-H352 AromaticContact CE1-CD2 3.96Å; H61-H352 AromaticContact CE1-NE2 3.22Å; H61-H352 PolarHBondContact CE1-NE2 3.43Å; H61-H352 AromaticContact NE2-CE1 3.88Å; H61-H352 AromaticContact NE2-NE2 3.14Å; H61-H352 PolarHBondContact NE2-NE2 3.48Å; H61-H352 VanDerWaalsContact NE2-NE2 3.14Å
62	C	63.3	Low	60.1	Low	39 Å²	39	83.1 Å²	83.1	26%	0.264	49%	0.487	S	S	.	.	P	Polyproline II helix	trans	-78.1	130.2	171.2	-56.1	0	0	0	0	108	I64 P479	C62-I64 PolarHBondContact O-N 3.22Å; C62-P479 HydrophobicContact CB-CG 4.16Å; C62-P479 WeakPolarHBondContact SG-CG 3.03Å
63	Q	62.6	Low	62.4	Low	193 Å²	193	82.1 Å²	82.1	90%	0.902	47%	0.469	S	S	*	.	P	Polyproline II helix	trans	-77.9	117.5	168.6	-82.3	-176.1	-15.4	0	0	108.4
64	I	66.9	Low	64.7	Low	36 Å²	36	78.9 Å²	78.9	19%	0.185	45%	0.452	C	S	.	.	P	Polyproline II helix	trans	-87.9	135.5	176.7	-55	177.2	0	0	0	107.6	C62 D344 A475 Y476	C62-I64 PolarHBondContact O-N 3.22Å; I64-D344 HydrophobicContact CD1-CB 3.61Å; I64-D344 WeakPolarHBondContact CD1-OD1 3.19Å; I64-A475 HydrophobicContact CG2-CB 4.45Å; I64-Y476 HydrophobicContact CD1-CE1 4.37Å; I64-Y476 HydrophobicContact CD1-CE2 4.1Å; I64-Y476 VanDerWaalsContact CD1-OH 3.28Å; I64-Y476 WeakPolarHBondContact CD1-OH 3.25Å
65	P	63.3	Low	66.6	Low	77 Å²	77	73.1 Å²	73.1	50%	0.5	42%	0.423	S	S	.	.	P	Polyproline II helix	trans	-60	143.3	171.7	24.7	-33	0	0	0	110.5	L67 V471	P65-L67 PolarHBondContact O-N 3.08Å; P65-V471 HydrophobicContact CG-CG1 4.37Å
66	D	60.1	Low	68.6	Low	128 Å²	128	67.6 Å²	67.6	68%	0.684	39%	0.388	S	S	*	.			trans	-62.7	104.6	174.8	-76.6	-47.8	0	0	0	109.8	K341	D66-K341 WeakPolarHBondContact OD1-CE 3.48Å; D66-K341 IonicContact OD1-NZ 2.67Å; D66-K341 PolarHBondContact OD1-NZ 3.45Å
67	L	61.5	Low	70.2	Confident	17 Å²	17	71.1 Å²	71.1	9%	0.089	40%	0.401	C	S	.	.			trans	-67.2	141.5	171.1	-74.2	140.9	0	0	0	108.9	P65 V69 S340 V471 L472	P65-L67 PolarHBondContact O-N 3.08Å; L67-V69 PolarHBondContact O-N 2.99Å; L67-S340 WeakPolarHBondContact CD1-OG 3.35Å; L67-V471 HydrophobicContact CD2-CB 3.79Å; L67-V471 HydrophobicContact CD2-CG1 3.55Å; L67-V471 HydrophobicContact CD2-CG2 4.18Å; L67-V471 HydrophobicContact CG-CG1 4.21Å; L67-L472 HydrophobicContact CD1-CD1 3.31Å
68	P	58.9	Low	71.8	Confident	88 Å²	88	71 Å²	71	57%	0.571	39%	0.387	S	S	*	.			trans	-61.9	104.8	171.2	26.6	-32.4	0	0	0	108
69	V	63.6	Low	73.4	Confident	97 Å²	97	66.7 Å²	66.7	59%	0.588	36%	0.358	S	S	*	.	P	Polyproline II helix	trans	-78.7	122.3	169.8	-176.4	0	0	0	0	105.6	L67 G71	L67-V69 PolarHBondContact O-N 2.99Å; V69-G71 PolarHBondContact O-N 2.97Å
70	D	65.2	Low	74.9	Confident	34 Å²	34	66.7 Å²	66.7	18%	0.182	36%	0.356	C	S	.	.	P	Polyproline II helix	trans	-52.6	135.9	171.8	-66.1	-20.1	0	0	0	108.4	S72 L74 Y460 K464	D70-S72 PolarHBondContact O-N 3.22Å; D70-L74 HydrophobicContact CB-CD2 3.94Å; D70-Y460 PolarHBondContact OD2-OH 3.41Å; D70-K464 WeakPolarHBondContact OD2-CE 2.77Å; D70-K464 IonicContact OD2-NZ 3.23Å; D70-K464 PolarHBondContact OD2-NZ 3.33Å
71	G	74.6	Confident	76.6	Confident	45 Å²	45	61.3 Å²	61.3	46%	0.464	34%	0.34	S	S	.	.	P	Polyproline II helix	trans	-52.3	138.3	173.5	0	0	0	0	0	109.8	V69 L73 L74 F75	V69-G71 PolarHBondContact O-N 2.97Å; G71-L73 PolarHBondContact O-N 3.42Å; G71-L73 VanDerWaalsContact O-N 3.09Å; G71-L74 PolarHBondContact O-N 2.98Å; G71-F75 PolarHBondContact O-N 3.34Å
72	S	80.5	Confident	77.7	Confident	52 Å²	52	58.4 Å²	58.4	36%	0.364	33%	0.326	S	S	.	.	H	α-helix	trans	-44.5	-45	177.6	52	0	0	0	0	111.6	D70 E76 E140	D70-S72 PolarHBondContact O-N 3.22Å; S72-E76 WeakPolarHBondContact O-CG 3.38Å; S72-E76 PolarHBondContact O-N 3.46Å; S72-E76 VanDerWaalsContact O-N 3.16Å; S72-E140 PolarHBondContact OG-OE2 3.33Å
73	L	84.4	Confident	79.3	Confident	64 Å²	64	56.6 Å²	56.6	34%	0.335	31%	0.314	S	S	.	.	H	α-helix	trans	-66.7	-41.9	178.3	-175.5	151.5	0	0	0	113.5	G71 E76 F77 L137 E140	G71-L73 PolarHBondContact O-N 3.42Å; G71-L73 VanDerWaalsContact O-N 3.09Å; L73-E76 PolarHBondContact O-N 2.97Å; L73-F77 WeakPolarHBondContact O-CB 3.12Å; L73-F77 PolarHBondContact O-N 2.86Å; L73-L137 HydrophobicContact CD1-CD2 3.53Å; L73-L137 HydrophobicContact CD1-CG 4.29Å; L73-L137 HydrophobicContact CG-CD2 4.26Å; L73-E140 HydrophobicContact CD1-CB 4.36Å
74	L	87.7	Confident	80.8	Confident	81 Å²	81	50.2 Å²	50.2	42%	0.424	29%	0.286	S	S	.	.	H	α-helix	trans	-66.4	-40.5	179.4	-178.1	140.8	0	0	0	111	D70 G71 F77 L78	D70-L74 HydrophobicContact CB-CD2 3.94Å; G71-L74 PolarHBondContact O-N 2.98Å; L74-F77 PolarHBondContact O-N 3.48Å; L74-L78 HydrophobicContact CD2-CD1 3.61Å; L74-L78 HydrophobicContact CD2-CG 4.32Å; L74-L78 HydrophobicContact CG-CD1 4.4Å; L74-L78 WeakPolarHBondContact O-CG 3.12Å; L74-L78 PolarHBondContact O-N 3.09Å
75	F	89.7	Confident	82.1	Confident	11 Å²	11	50.3 Å²	50.3	5%	0.048	29%	0.288	C	S	.	.	H	α-helix	trans	-59.7	-50.4	172.9	174.1	-84.8	0	0	0	111.4	G71 F77 L78 F79 M332 Q336	G71-F75 PolarHBondContact O-N 3.34Å; F75-F77 VanDerWaalsContact C-N 3.25Å; F75-F77 PolarHBondContact O-N 2.95Å; F75-L78 PolarHBondContact O-N 2.82Å; F75-F79 HydrophobicContact CE1-CB 4.07Å; F75-F79 HydrophobicContact CE1-CG 4.36Å; F75-F79 HydrophobicContact CZ-CB 4.41Å; F75-F79 WeakPolarHBondContact O-CB 3.17Å; F75-F79 PolarHBondContact O-N 3.27Å; F75-M332 HydrophobicContact CE2-CB 4.32Å; F75-M332 VanDerWaalsContact CE2-O 3.27Å; F75-M332 WeakPolarHBondContact CE2-O 3.48Å; F75-M332 HydrophobicContact CZ-CB 4.19Å; F75-M332 VanDerWaalsContact CZ-O 3.29Å; F75-M332 WeakPolarHBondContact CZ-O 3.3Å; F75-Q336 HydrophobicContact CD1-CB 4.11Å; F75-Q336 HydrophobicContact CD1-CG 3.76Å; F75-Q336 VanDerWaalsContact CD1-OE1 3.23Å; F75-Q336 HydrophobicContact CD2-CB 4.09Å; F75-Q336 HydrophobicContact CD2-CG 4.35Å; F75-Q336 HydrophobicContact CE1-CB 3.84Å; F75-Q336 HydrophobicContact CE1-CG 3.9Å; F75-Q336 HydrophobicContact CE2-CB 3.78Å; F75-Q336 HydrophobicContact CE2-CG 4.44Å; F75-Q336 HydrophobicContact CG-CB 4.24Å; F75-Q336 HydrophobicContact CG-CG 4.01Å; F75-Q336 HydrophobicContact CZ-CB 3.64Å; F75-Q336 HydrophobicContact CZ-CG 4.22Å
76	E	90.5	Very high	83.7	Confident	2 Å²	2	46.7 Å²	46.7	1%	0.009	27%	0.265	C	S	.	.	H	α-helix	trans	-63.6	-34.3	-178.7	-68.4	-62.9	162.1	0	0	112	S72 L73 F80 R132 L133 A136 N254 Q336	S72-E76 WeakPolarHBondContact O-CG 3.38Å; S72-E76 PolarHBondContact O-N 3.46Å; S72-E76 VanDerWaalsContact O-N 3.16Å; L73-E76 PolarHBondContact O-N 2.97Å; E76-F80 VanDerWaalsContact O-CB 3.26Å; E76-F80 WeakPolarHBondContact O-CB 3.41Å; E76-F80 PolarHBondContact O-N 3.05Å; E76-R132 IonicContact OE1-CZ 3.62Å; E76-R132 VanDerWaalsContact OE1-CZ 3.23Å; E76-R132 IonicContact OE1-NE 2.95Å; E76-R132 IonicContact OE1-NH1 3.02Å; E76-R132 PolarHBondContact OE1-NH1 3.41Å; E76-R132 IonicContact OE1-NH2 3.76Å; E76-R132 PolarHBondContact OE1-NH2 3.21Å; E76-R132 WeakPolarHBondContact OE2-CB 3.17Å; E76-R132 IonicContact OE2-CZ 3.81Å; E76-R132 IonicContact OE2-NE 3.75Å; E76-R132 IonicContact OE2-NH1 3.9Å; E76-R132 PolarHBondContact OE2-NH1 3.17Å; E76-R132 IonicContact OE2-NH2 3.46Å; E76-L133 HydrophobicContact CB-CD1 4.1Å; E76-A136 HydrophobicContact CB-CB 4.13Å; E76-A136 HydrophobicContact CG-CB 3.82Å; E76-N254 PolarHBondContact OE1-ND2 3.45Å; E76-Q336 PolarHBondContact OE1-NE2 3.34Å; E76-Q336 PolarHBondContact OE1-OE1 3.49Å
77	F	91.2	Very high	85.3	Confident	103 Å²	103	41 Å²	41	45%	0.452	23%	0.234	S	C	.	.	H	α-helix	trans	-65.8	-48.2	174.7	178.5	-106.5	0	0	0	112.1	L73 L74 F75 F79 F80 I81 L133	L73-F77 WeakPolarHBondContact O-CB 3.12Å; L73-F77 PolarHBondContact O-N 2.86Å; L74-F77 PolarHBondContact O-N 3.48Å; F75-F77 VanDerWaalsContact C-N 3.25Å; F75-F77 PolarHBondContact O-N 2.95Å; F77-F79 VanDerWaalsContact C-N 3.34Å; F77-F79 PolarHBondContact O-N 2.99Å; F77-F80 PolarHBondContact O-N 3.46Å; F77-I81 HydrophobicContact CD1-CD1 3.85Å; F77-I81 HydrophobicContact CE1-CD1 3.3Å; F77-I81 HydrophobicContact CE1-CG1 4.4Å; F77-I81 HydrophobicContact CE2-CD1 4.09Å; F77-I81 HydrophobicContact CE2-CG1 4.48Å; F77-I81 HydrophobicContact CG-CD1 4.46Å; F77-I81 HydrophobicContact CZ-CD1 3.45Å; F77-I81 VanDerWaalsContact CZ-CD1 3.45Å; F77-I81 HydrophobicContact CZ-CG1 4.29Å; F77-I81 WeakPolarHBondContact O-CG1 3.3Å; F77-I81 PolarHBondContact O-N 2.9Å; F77-L133 HydrophobicContact CB-CD1 4.12Å; F77-L133 HydrophobicContact CD2-CD2 4.36Å
78	L	91.8	Very high	86.8	Confident	53 Å²	53	45.4 Å²	45.4	28%	0.277	25%	0.253	S	S	.	.	H	α-helix	trans	-63.6	-40.4	176.5	-70.6	176.6	0	0	0	111.8	L74 F75 I81 Y82 Y460	L74-L78 HydrophobicContact CD2-CD1 3.61Å; L74-L78 HydrophobicContact CD2-CG 4.32Å; L74-L78 HydrophobicContact CG-CD1 4.4Å; L74-L78 WeakPolarHBondContact O-CG 3.12Å; L74-L78 PolarHBondContact O-N 3.09Å; F75-L78 PolarHBondContact O-N 2.82Å; L78-I81 PolarHBondContact O-N 3.33Å; L78-Y82 WeakPolarHBondContact O-CB 3.25Å; L78-Y82 PolarHBondContact O-N 3.45Å; L78-Y460 HydrophobicContact CD1-CE1 3.65Å
79	F	93.1	Very high	88.4	Confident	5 Å²	5	41.2 Å²	41.2	2%	0.022	23%	0.226	C	C	.	.	H	α-helix	trans	-62.7	-43.1	174.9	-175.3	-111.8	0	0	0	111.3	F75 F77 Y82 L83 R132 A329 M332 L333	F75-F79 HydrophobicContact CE1-CB 4.07Å; F75-F79 HydrophobicContact CE1-CG 4.36Å; F75-F79 HydrophobicContact CZ-CB 4.41Å; F75-F79 WeakPolarHBondContact O-CB 3.17Å; F75-F79 PolarHBondContact O-N 3.27Å; F77-F79 VanDerWaalsContact C-N 3.34Å; F77-F79 PolarHBondContact O-N 2.99Å; F79-Y82 HydrophobicContact CD2-CD1 4.32Å; F79-Y82 HydrophobicContact CE2-CD1 4.4Å; F79-Y82 WeakPolarHBondContact O-CB 3.5Å; F79-Y82 PolarHBondContact O-N 3.38Å; F79-L83 HydrophobicContact CD1-CD1 3.81Å; F79-L83 HydrophobicContact CD1-CG 4.49Å; F79-L83 HydrophobicContact CE1-CD1 3.4Å; F79-L83 VanDerWaalsContact CE1-CD1 3.4Å; F79-L83 HydrophobicContact CE1-CG 4.23Å; F79-L83 HydrophobicContact CE2-CD1 4.45Å; F79-L83 HydrophobicContact CE2-CD2 4.47Å; F79-L83 HydrophobicContact CE2-CG 4.46Å; F79-L83 HydrophobicContact CZ-CD1 3.77Å; F79-L83 HydrophobicContact CZ-CD2 4.24Å; F79-L83 HydrophobicContact CZ-CG 4.21Å; F79-L83 VanDerWaalsContact O-CG 3.31Å; F79-L83 WeakPolarHBondContact O-CG 3.38Å; F79-L83 PolarHBondContact O-N 3.11Å; F79-R132 VanDerWaalsContact CD1-NH1 3.26Å; F79-R132 VanDerWaalsContact CE1-NH1 3.26Å; F79-A329 HydrophobicContact CE2-CB 4.01Å; F79-A329 HydrophobicContact CZ-CB 4.28Å; F79-M332 HydrophobicContact CB-CE 4.18Å; F79-M332 HydrophobicContact CD2-CB 4.14Å; F79-M332 HydrophobicContact CD2-CE 3.92Å; F79-M332 HydrophobicContact CD2-SD 3.94Å; F79-M332 HydrophobicContact CE2-CB 4.38Å; F79-L333 HydrophobicContact CE1-CD2 4.38Å; F79-L333 HydrophobicContact CE2-CG 4.21Å; F79-L333 HydrophobicContact CZ-CD1 4.1Å; F79-L333 HydrophobicContact CZ-CD2 4.21Å; F79-L333 HydrophobicContact CZ-CG 4.09Å
80	F	94.4	Very high	89.8	Confident	30 Å²	30	36.6 Å²	36.6	13%	0.132	20%	0.198	C	C	.	.	H	α-helix	trans	-62.9	-44.8	175.4	179.1	-115.2	0	0	0	112.4	E76 F77 Y82 L83 L84 T126 L129 A130 L133	E76-F80 VanDerWaalsContact O-CB 3.26Å; E76-F80 WeakPolarHBondContact O-CB 3.41Å; E76-F80 PolarHBondContact O-N 3.05Å; F77-F80 PolarHBondContact O-N 3.46Å; F80-Y82 VanDerWaalsContact C-N 3.32Å; F80-Y82 PolarHBondContact O-N 3.42Å; F80-L83 PolarHBondContact O-N 3.33Å; F80-L84 HydrophobicContact CD1-CD1 4.02Å; F80-L84 HydrophobicContact CD1-CG 4.47Å; F80-L84 HydrophobicContact CD2-CG 4.46Å; F80-L84 HydrophobicContact CE1-CD1 3.46Å; F80-L84 VanDerWaalsContact CE1-CD1 3.46Å; F80-L84 HydrophobicContact CE1-CG 4.09Å; F80-L84 HydrophobicContact CE2-CD1 4.31Å; F80-L84 HydrophobicContact CE2-CD2 4.1Å; F80-L84 HydrophobicContact CE2-CG 4.05Å; F80-L84 HydrophobicContact CZ-CD1 3.63Å; F80-L84 HydrophobicContact CZ-CD2 3.96Å; F80-L84 HydrophobicContact CZ-CG 3.86Å; F80-L84 WeakPolarHBondContact O-CG 3.48Å; F80-L84 PolarHBondContact O-N 2.83Å; F80-T126 HydrophobicContact CZ-CG2 4.25Å; F80-L129 HydrophobicContact CD2-CB 4.24Å; F80-L129 HydrophobicContact CE2-CB 4.08Å; F80-A130 HydrophobicContact CD2-CB 4.3Å; F80-A130 HydrophobicContact CE2-CB 3.63Å; F80-A130 HydrophobicContact CZ-CB 3.89Å; F80-L133 HydrophobicContact CB-CD2 4.08Å; F80-L133 HydrophobicContact CD1-CD2 3.65Å; F80-L133 HydrophobicContact CE1-CD2 4.29Å; F80-L133 HydrophobicContact CG-CD2 3.95Å
81	I	93.9	Very high	91	Very high	66 Å²	66	35.7 Å²	35.7	34%	0.338	19%	0.192	S	C	.	.	H	α-helix	trans	-58	-46.8	174.3	-72	173.2	0	0	0	110.7	F77 L78 L83 L84 V85	F77-I81 HydrophobicContact CD1-CD1 3.85Å; F77-I81 HydrophobicContact CE1-CD1 3.3Å; F77-I81 HydrophobicContact CE1-CG1 4.4Å; F77-I81 HydrophobicContact CE2-CD1 4.09Å; F77-I81 HydrophobicContact CE2-CG1 4.48Å; F77-I81 HydrophobicContact CG-CD1 4.46Å; F77-I81 HydrophobicContact CZ-CD1 3.45Å; F77-I81 VanDerWaalsContact CZ-CD1 3.45Å; F77-I81 HydrophobicContact CZ-CG1 4.29Å; F77-I81 WeakPolarHBondContact O-CG1 3.3Å; F77-I81 PolarHBondContact O-N 2.9Å; L78-I81 PolarHBondContact O-N 3.33Å; I81-L83 VanDerWaalsContact C-N 3.31Å; I81-L83 PolarHBondContact O-N 3.44Å; I81-L84 PolarHBondContact O-N 3.09Å; I81-V85 HydrophobicContact CG2-CG2 4.33Å; I81-V85 WeakPolarHBondContact O-CG2 3.34Å; I81-V85 PolarHBondContact O-N 2.91Å
82	Y	94.9	Very high	91.7	Very high	5 Å²	5	33.8 Å²	33.8	2%	0.02	17%	0.171	C	C	.	.	H	α-helix	trans	-56.4	-46.1	177.1	160.9	-106.3	0	0	0	111.8	L78 F79 F80 L84 V85 A86 V325 N328 A329 M332 C457	L78-Y82 WeakPolarHBondContact O-CB 3.25Å; L78-Y82 PolarHBondContact O-N 3.45Å; F79-Y82 HydrophobicContact CD2-CD1 4.32Å; F79-Y82 HydrophobicContact CE2-CD1 4.4Å; F79-Y82 WeakPolarHBondContact O-CB 3.5Å; F79-Y82 PolarHBondContact O-N 3.38Å; F80-Y82 VanDerWaalsContact C-N 3.32Å; F80-Y82 PolarHBondContact O-N 3.42Å; Y82-L84 PolarHBondContact O-N 3.09Å; Y82-V85 PolarHBondContact O-N 2.84Å; Y82-A86 WeakPolarHBondContact O-CB 3.38Å; Y82-A86 PolarHBondContact O-N 3.02Å; Y82-V325 VanDerWaalsContact OH-CA 3.29Å; Y82-V325 WeakPolarHBondContact OH-CA 3.42Å; Y82-V325 PolarHBondContact OH-O 3.34Å; Y82-N328 WeakPolarHBondContact CE2-ND2 3.35Å; Y82-N328 WeakPolarHBondContact OH-CB 3.19Å; Y82-N328 PolarHBondContact OH-ND2 3.48Å; Y82-A329 HydrophobicContact CE1-CB 4.4Å; Y82-M332 HydrophobicContact CD1-SD 3.79Å; Y82-M332 HydrophobicContact CE1-SD 4.27Å; Y82-M332 HydrophobicContact CG-SD 4.01Å; Y82-C457 HydrophobicContact CD2-CB 3.83Å; Y82-C457 HydrophobicContact CE2-CB 4.49Å
83	L	95.6	Very high	92	Very high	2 Å²	2	31.5 Å²	31.5	1%	0.01	15%	0.154	C	C	.	.	H	α-helix	trans	-66.7	-35.4	178.7	-65.2	174.8	0	0	0	112.7	F79 F80 I81 A86 L87 L129 V299	F79-L83 HydrophobicContact CD1-CD1 3.81Å; F79-L83 HydrophobicContact CD1-CG 4.49Å; F79-L83 HydrophobicContact CE1-CD1 3.4Å; F79-L83 VanDerWaalsContact CE1-CD1 3.4Å; F79-L83 HydrophobicContact CE1-CG 4.23Å; F79-L83 HydrophobicContact CE2-CD1 4.45Å; F79-L83 HydrophobicContact CE2-CD2 4.47Å; F79-L83 HydrophobicContact CE2-CG 4.46Å; F79-L83 HydrophobicContact CZ-CD1 3.77Å; F79-L83 HydrophobicContact CZ-CD2 4.24Å; F79-L83 HydrophobicContact CZ-CG 4.21Å; F79-L83 VanDerWaalsContact O-CG 3.31Å; F79-L83 WeakPolarHBondContact O-CG 3.38Å; F79-L83 PolarHBondContact O-N 3.11Å; F80-L83 PolarHBondContact O-N 3.33Å; I81-L83 VanDerWaalsContact C-N 3.31Å; I81-L83 PolarHBondContact O-N 3.44Å; L83-A86 PolarHBondContact O-N 3.18Å; L83-L87 VanDerWaalsContact O-CB 3.28Å; L83-L87 WeakPolarHBondContact O-CB 3.28Å; L83-L87 PolarHBondContact O-N 3.41Å; L83-L129 HydrophobicContact CB-CD1 4.09Å; L83-L129 HydrophobicContact CD1-CD2 4.13Å; L83-V299 HydrophobicContact CB-CG2 4.18Å; L83-V299 HydrophobicContact CD2-CG2 3.96Å
84	L	95.3	Very high	92.2	Very high	58 Å²	58	28.4 Å²	28.4	30%	0.304	14%	0.138	S	C	.	.	H	α-helix	trans	-64.9	-43.4	172.8	-73.3	-178	0	0	0	112.1	F80 I81 Y82 L87 F88 T126	F80-L84 HydrophobicContact CD1-CD1 4.02Å; F80-L84 HydrophobicContact CD1-CG 4.47Å; F80-L84 HydrophobicContact CD2-CG 4.46Å; F80-L84 HydrophobicContact CE1-CD1 3.46Å; F80-L84 VanDerWaalsContact CE1-CD1 3.46Å; F80-L84 HydrophobicContact CE1-CG 4.09Å; F80-L84 HydrophobicContact CE2-CD1 4.31Å; F80-L84 HydrophobicContact CE2-CD2 4.1Å; F80-L84 HydrophobicContact CE2-CG 4.05Å; F80-L84 HydrophobicContact CZ-CD1 3.63Å; F80-L84 HydrophobicContact CZ-CD2 3.96Å; F80-L84 HydrophobicContact CZ-CG 3.86Å; F80-L84 WeakPolarHBondContact O-CG 3.48Å; F80-L84 PolarHBondContact O-N 2.83Å; I81-L84 PolarHBondContact O-N 3.09Å; Y82-L84 PolarHBondContact O-N 3.09Å; L84-L87 PolarHBondContact O-N 3.01Å; L84-F88 WeakPolarHBondContact O-CB 3.35Å; L84-F88 PolarHBondContact O-N 3.27Å; L84-T126 HydrophobicContact CD2-CG2 3.97Å
85	V	94.9	Very high	92.1	Very high	39 Å²	39	25 Å²	25	24%	0.236	12%	0.12	C	C	.	.	H	α-helix	trans	-61.8	-46.5	175.2	170.9	0	0	0	0	110	I81 Y82 L87 F88 I89 L453	I81-V85 HydrophobicContact CG2-CG2 4.33Å; I81-V85 WeakPolarHBondContact O-CG2 3.34Å; I81-V85 PolarHBondContact O-N 2.91Å; Y82-V85 PolarHBondContact O-N 2.84Å; V85-L87 VanDerWaalsContact C-N 3.32Å; V85-L87 PolarHBondContact O-N 3.46Å; V85-F88 PolarHBondContact O-N 3.09Å; V85-I89 HydrophobicContact CG1-CD1 3.8Å; V85-I89 WeakPolarHBondContact O-CB 3.36Å; V85-I89 WeakPolarHBondContact O-CD1 3.41Å; V85-I89 WeakPolarHBondContact O-CG1 3.41Å; V85-I89 PolarHBondContact O-N 2.92Å; V85-L453 HydrophobicContact CG1-CB 4.17Å
86	A	95	Very high	91.8	Very high	1 Å²	1	26.7 Å²	26.7	1%	0.008	13%	0.127	C	C	.	.	H	α-helix	trans	-63.5	-35.8	177.9	0	0	0	0	0	112.9	Y82 L83 Q90 V299 H321 V325	Y82-A86 WeakPolarHBondContact O-CB 3.38Å; Y82-A86 PolarHBondContact O-N 3.02Å; L83-A86 PolarHBondContact O-N 3.18Å; A86-Q90 PolarHBondContact O-N 3.34Å; A86-Q90 VanDerWaalsContact O-N 3.1Å; A86-V299 HydrophobicContact CB-CG1 3.61Å; A86-H321 PolarHBondContact O-NE2 3.43Å; A86-V325 HydrophobicContact CB-CG1 4.44Å; A86-V325 HydrophobicContact CB-CG2 3.81Å
87	L	95.1	Very high	91	Very high	8 Å²	8	27 Å²	27	4%	0.042	13%	0.13	C	C	.	.	H	α-helix	trans	-67.3	-48.2	174.7	-179.4	65.4	0	0	0	110.7	L83 L84 V85 I89 Q90 Y91 I125 L129 V299 P303	L83-L87 VanDerWaalsContact O-CB 3.28Å; L83-L87 WeakPolarHBondContact O-CB 3.28Å; L83-L87 PolarHBondContact O-N 3.41Å; L84-L87 PolarHBondContact O-N 3.01Å; V85-L87 VanDerWaalsContact C-N 3.32Å; V85-L87 PolarHBondContact O-N 3.46Å; L87-I89 VanDerWaalsContact C-N 3.25Å; L87-I89 PolarHBondContact O-N 2.96Å; L87-Q90 WeakPolarHBondContact O-CB 3.42Å; L87-Q90 PolarHBondContact O-N 2.9Å; L87-Y91 HydrophobicContact CD1-CD2 4.03Å; L87-Y91 HydrophobicContact CD1-CE2 3.55Å; L87-Y91 HydrophobicContact CD2-CE2 4.27Å; L87-Y91 HydrophobicContact CG-CD2 3.93Å; L87-Y91 HydrophobicContact CG-CE2 3.7Å; L87-Y91 VanDerWaalsContact O-CD2 3.25Å; L87-Y91 WeakPolarHBondContact O-CD2 2.96Å; L87-Y91 PolarHBondContact O-N 2.94Å; L87-I125 HydrophobicContact CD1-CD1 4.32Å; L87-I125 HydrophobicContact CD1-CG2 3.86Å; L87-I125 HydrophobicContact CD2-CB 4.38Å; L87-I125 HydrophobicContact CD2-CG2 3.73Å; L87-I125 HydrophobicContact CG-CG2 4.44Å; L87-L129 HydrophobicContact CD2-CD1 4.38Å; L87-V299 HydrophobicContact CB-CG1 4.32Å; L87-P303 HydrophobicContact CD1-CG 4.03Å
88	F	92.7	Very high	90	Very high	110 Å²	110	26.3 Å²	26.3	48%	0.482	13%	0.133	S	C	.	.	H	α-helix	trans	-56.6	-42.1	176.9	176.8	-113.9	0	0	0	111.8	L84 V85 Q90 Y91 I92	L84-F88 WeakPolarHBondContact O-CB 3.35Å; L84-F88 PolarHBondContact O-N 3.27Å; V85-F88 PolarHBondContact O-N 3.09Å; F88-Q90 VanDerWaalsContact C-N 3.34Å; F88-Q90 PolarHBondContact O-N 3.25Å; F88-Y91 PolarHBondContact O-N 3.42Å; F88-I92 HydrophobicContact CD1-CD1 3.74Å; F88-I92 HydrophobicContact CE1-CD1 3.31Å; F88-I92 HydrophobicContact CE1-CG1 4.28Å; F88-I92 HydrophobicContact CE2-CD1 4.3Å; F88-I92 HydrophobicContact CE2-CG1 4.45Å; F88-I92 HydrophobicContact CG-CD1 4.41Å; F88-I92 HydrophobicContact CZ-CD1 3.63Å; F88-I92 HydrophobicContact CZ-CG1 4.18Å; F88-I92 WeakPolarHBondContact O-CG1 3.42Å; F88-I92 PolarHBondContact O-N 3.5Å
89	I	92.3	Very high	88.8	Confident	0 Å²	0	30.7 Å²	30.7	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-62.9	-41	175.7	-71.6	168.9	0	0	0	111.9	V85 L87 Y91 I92 N93 L453 I454	V85-I89 HydrophobicContact CG1-CD1 3.8Å; V85-I89 WeakPolarHBondContact O-CB 3.36Å; V85-I89 WeakPolarHBondContact O-CD1 3.41Å; V85-I89 WeakPolarHBondContact O-CG1 3.41Å; V85-I89 PolarHBondContact O-N 2.92Å; L87-I89 VanDerWaalsContact C-N 3.25Å; L87-I89 PolarHBondContact O-N 2.96Å; I89-Y91 VanDerWaalsContact C-N 3.32Å; I89-Y91 PolarHBondContact O-N 2.89Å; I89-I92 WeakPolarHBondContact O-CB 3.13Å; I89-I92 PolarHBondContact O-N 3.44Å; I89-N93 PolarHBondContact O-N 3.22Å; I89-N93 PolarHBondContact O-ND2 3.28Å; I89-L453 HydrophobicContact CD1-CB 3.56Å; I89-L453 HydrophobicContact CD1-CD1 4.2Å; I89-L453 HydrophobicContact CG1-CB 4.33Å; I89-L453 HydrophobicContact CG1-CD1 4.06Å; I89-I454 HydrophobicContact CD1-CD1 4.11Å; I89-I454 HydrophobicContact CD1-CG1 3.45Å; I89-I454 VanDerWaalsContact CD1-CG1 3.45Å; I89-I454 HydrophobicContact CG2-CD1 4.3Å
90	Q	93.1	Very high	87.6	Confident	0 Å²	0	36.9 Å²	36.9	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-63.1	-41.2	176	-172.3	66	-10.1	0	0	111.5	A86 L87 F88 I92 N93 I94 A300 P303 H321	A86-Q90 PolarHBondContact O-N 3.34Å; A86-Q90 VanDerWaalsContact O-N 3.1Å; L87-Q90 WeakPolarHBondContact O-CB 3.42Å; L87-Q90 PolarHBondContact O-N 2.9Å; F88-Q90 VanDerWaalsContact C-N 3.34Å; F88-Q90 PolarHBondContact O-N 3.25Å; Q90-I92 PolarHBondContact O-N 3.02Å; Q90-N93 PolarHBondContact O-N 3.17Å; Q90-I94 HydrophobicContact CG-CD1 3.91Å; Q90-I94 VanDerWaalsContact O-CG1 3.29Å; Q90-I94 WeakPolarHBondContact O-CG1 3.4Å; Q90-I94 PolarHBondContact O-N 3.07Å; Q90-A300 PolarHBondContact NE2-O 3.07Å; Q90-P303 HydrophobicContact CG-CB 4.23Å; Q90-P303 HydrophobicContact CG-CG 4.28Å; Q90-H321 PolarHBondContact OE1-CD2 2.97Å
91	Y	90.7	Very high	85.7	Confident	15 Å²	15	43.8 Å²	43.8	6%	0.059	20%	0.196	C	C	.	.	H	α-helix	trans	-62.6	-39.4	173.3	-81.1	-76.5	0	0	0	112.6	L87 F88 I89 N93 I94 Y95 I117 A122	L87-Y91 HydrophobicContact CD1-CD2 4.03Å; L87-Y91 HydrophobicContact CD1-CE2 3.55Å; L87-Y91 HydrophobicContact CD2-CE2 4.27Å; L87-Y91 HydrophobicContact CG-CD2 3.93Å; L87-Y91 HydrophobicContact CG-CE2 3.7Å; L87-Y91 VanDerWaalsContact O-CD2 3.25Å; L87-Y91 WeakPolarHBondContact O-CD2 2.96Å; L87-Y91 PolarHBondContact O-N 2.94Å; F88-Y91 PolarHBondContact O-N 3.42Å; I89-Y91 VanDerWaalsContact C-N 3.32Å; I89-Y91 PolarHBondContact O-N 2.89Å; Y91-N93 VanDerWaalsContact C-N 3.33Å; Y91-N93 PolarHBondContact O-N 3.05Å; Y91-I94 PolarHBondContact O-N 3.1Å; Y91-Y95 AromaticContact CD1-CD2 3.66Å; Y91-Y95 HydrophobicContact CD1-CD2 3.66Å; Y91-Y95 AromaticContact CD1-CE2 3.44Å; Y91-Y95 HydrophobicContact CD1-CE2 3.44Å; Y91-Y95 VanDerWaalsContact CD1-CE2 3.44Å; Y91-Y95 HydrophobicContact CE1-CD2 4.43Å; Y91-Y95 AromaticContact CE1-CE2 3.77Å; Y91-Y95 HydrophobicContact CE1-CE2 3.77Å; Y91-Y95 WeakPolarHBondContact O-CD2 3.4Å; Y91-Y95 PolarHBondContact O-N 3.08Å; Y91-I117 HydrophobicContact CD1-CD1 4.27Å; Y91-I117 HydrophobicContact CD1-CG1 4.22Å; Y91-I117 HydrophobicContact CD1-CG2 4.02Å; Y91-I117 HydrophobicContact CE1-CG2 3.8Å; Y91-A122 HydrophobicContact CE2-CB 4.29Å; Y91-A122 WeakPolarHBondContact OH-CA 3.41Å; Y91-A122 WeakPolarHBondContact OH-CB 3.48Å
92	I	88.8	Confident	83.7	Confident	4 Å²	4	45.1 Å²	45.1	2%	0.021	21%	0.209	C	C	.	.	H	α-helix	trans	-59.5	-45.7	173	-70.9	164.9	0	0	0	110.7	F88 I89 Q90 I94 K96 L112 W445 N446 L449	F88-I92 HydrophobicContact CD1-CD1 3.74Å; F88-I92 HydrophobicContact CE1-CD1 3.31Å; F88-I92 HydrophobicContact CE1-CG1 4.28Å; F88-I92 HydrophobicContact CE2-CD1 4.3Å; F88-I92 HydrophobicContact CE2-CG1 4.45Å; F88-I92 HydrophobicContact CG-CD1 4.41Å; F88-I92 HydrophobicContact CZ-CD1 3.63Å; F88-I92 HydrophobicContact CZ-CG1 4.18Å; F88-I92 WeakPolarHBondContact O-CG1 3.42Å; F88-I92 PolarHBondContact O-N 3.5Å; I89-I92 WeakPolarHBondContact O-CB 3.13Å; I89-I92 PolarHBondContact O-N 3.44Å; Q90-I92 PolarHBondContact O-N 3.02Å; I92-I94 VanDerWaalsContact C-N 3.3Å; I92-I94 PolarHBondContact O-N 2.84Å; I92-K96 WeakPolarHBondContact O-CB 3.44Å; I92-K96 PolarHBondContact O-N 3.14Å; I92-K96 VanDerWaalsContact O-N 3.17Å; I92-L112 HydrophobicContact CB-CD2 4.29Å; I92-L112 HydrophobicContact CG1-CD1 4.03Å; I92-L112 HydrophobicContact CG1-CD2 4.09Å; I92-L112 HydrophobicContact CG2-CD2 4.41Å; I92-W445 HydrophobicContact CG2-CH2 4.07Å; I92-W445 HydrophobicContact CG2-CZ3 4.24Å; I92-N446 HydrophobicContact CG2-CB 4.22Å; I92-L449 HydrophobicContact CD1-CD2 4.07Å
93	N	87.8	Confident	81.7	Confident	4 Å²	4	54 Å²	54	2%	0.021	24%	0.244	C	C	.	.	H	α-helix	trans	-66.3	-32.3	-177.1	-73	-30.7	0	0	0	113.1	I89 Q90 Y91 W317	I89-N93 PolarHBondContact O-N 3.22Å; I89-N93 PolarHBondContact O-ND2 3.28Å; Q90-N93 PolarHBondContact O-N 3.17Å; Y91-N93 VanDerWaalsContact C-N 3.33Å; Y91-N93 PolarHBondContact O-N 3.05Å; N93-W317 PolarHBondContact ND2-NE1 2.89Å
94	I	88.1	Confident	79.3	Confident	0 Å²	0	61.4 Å²	61.4	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-82.1	-47.1	179.6	-65.3	168.3	0	0	0	111.9	Q90 Y91 I92 P303 L304 V307 Q311	Q90-I94 HydrophobicContact CG-CD1 3.91Å; Q90-I94 VanDerWaalsContact O-CG1 3.29Å; Q90-I94 WeakPolarHBondContact O-CG1 3.4Å; Q90-I94 PolarHBondContact O-N 3.07Å; Y91-I94 PolarHBondContact O-N 3.1Å; I92-I94 VanDerWaalsContact C-N 3.3Å; I92-I94 PolarHBondContact O-N 2.84Å; I94-P303 HydrophobicContact CD1-CB 3.78Å; I94-L304 HydrophobicContact CD1-CD2 3.74Å; I94-L304 HydrophobicContact CD1-CG 4.48Å; I94-L304 HydrophobicContact CG1-CD2 3.95Å; I94-V307 HydrophobicContact CD1-CG2 4.12Å; I94-V307 HydrophobicContact CG1-CG2 4.45Å; I94-V307 HydrophobicContact CG2-CG1 4.29Å; I94-V307 HydrophobicContact CG2-CG2 3.52Å; I94-Q311 PolarHBondContact O-NE2 3.01Å
95	Y	85.9	Confident	77.4	Confident	8 Å²	8	66.7 Å²	66.7	3%	0.031	31%	0.306	C	S	.	.	H	α-helix	trans	-107.2	20.4	-167.3	-60.3	-76.3	0	0	0	114.3	Y91 L112 N113 L116 I117	Y91-Y95 AromaticContact CD1-CD2 3.66Å; Y91-Y95 HydrophobicContact CD1-CD2 3.66Å; Y91-Y95 AromaticContact CD1-CE2 3.44Å; Y91-Y95 HydrophobicContact CD1-CE2 3.44Å; Y91-Y95 VanDerWaalsContact CD1-CE2 3.44Å; Y91-Y95 HydrophobicContact CE1-CD2 4.43Å; Y91-Y95 AromaticContact CE1-CE2 3.77Å; Y91-Y95 HydrophobicContact CE1-CE2 3.77Å; Y91-Y95 WeakPolarHBondContact O-CD2 3.4Å; Y91-Y95 PolarHBondContact O-N 3.08Å; Y95-L112 WeakPolarHBondContact O-CA 3.4Å; Y95-N113 PolarHBondContact O-N 2.8Å; Y95-L116 HydrophobicContact CD1-CB 3.57Å; Y95-L116 HydrophobicContact CE1-CB 3.62Å; Y95-L116 VanDerWaalsContact CE1-O 3.27Å; Y95-L116 WeakPolarHBondContact CE1-O 3.31Å; Y95-L116 PolarHBondContact OH-O 3.15Å; Y95-I117 HydrophobicContact CD1-CG1 4.31Å; Y95-I117 HydrophobicContact CD2-CD1 4.27Å; Y95-I117 HydrophobicContact CD2-CG1 3.67Å; Y95-I117 HydrophobicContact CE2-CG1 3.92Å; Y95-I117 HydrophobicContact CG-CG1 3.85Å
96	K	82.6	Confident	75.3	Confident	48 Å²	48	71 Å²	71	21%	0.209	34%	0.335	C	S	.	.	B	Isolated β-bridge	trans	-54	143.8	177	64.7	-170.9	-178.5	-169.4	0	113	I92 W445 N446	I92-K96 WeakPolarHBondContact O-CB 3.44Å; I92-K96 PolarHBondContact O-N 3.14Å; I92-K96 VanDerWaalsContact O-N 3.17Å; K96-W445 HydrophobicContact CB-CZ2 4.12Å; K96-N446 HydrophobicContact CD-CB 4.3Å; K96-N446 WeakPolarHBondContact CD-ND2 3.46Å; K96-N446 PolarHBondContact NZ-ND2 2.88Å
97	T	74.2	Confident	73.1	Confident	9 Å²	9	73.5 Å²	73.5	6%	0.055	36%	0.355	C	S	.	.			trans	-120.7	159.6	169.4	63.9	0	0	0	0	111.3	W99 S108 T110 S111 N113	T97-W99 VanDerWaalsContact C-N 3.34Å; T97-W99 PolarHBondContact O-N 3.39Å; T97-S108 WeakPolarHBondContact CB-OG 3.48Å; T97-T110 PolarHBondContact OG1-O 2.84Å; T97-S111 PolarHBondContact N-O 3.3Å; T97-S111 WeakPolarHBondContact OG1-CA 2.92Å; T97-S111 PolarHBondContact OG1-O 2.9Å; T97-N113 HydrophobicContact CG2-CB 4.12Å; T97-N113 WeakPolarHBondContact CG2-ND2 3.32Å; T97-N113 WeakPolarHBondContact CG2-OD1 3.49Å
98	V	69.9	Low	71.2	Confident	88 Å²	88	74.8 Å²	74.8	53%	0.533	37%	0.365	S	S	.	.			trans	-93.5	73.4	169.4	-170.3	0	0	0	0	107.7	W100	V98-W100 VanDerWaalsContact C-N 3.26Å; V98-W100 HydrophobicContact CG1-CD2 4.28Å; V98-W100 HydrophobicContact CG1-CH2 4.13Å; V98-W100 HydrophobicContact CG1-CZ2 3.77Å; V98-W100 PolarHBondContact O-N 2.98Å
99	W	67.1	Low	69.6	Low	144 Å²	144	75.7 Å²	75.7	55%	0.545	38%	0.384	S	S	.	.	T	Hydrogen-bonded Turn	trans	-73.2	-15.5	-173	66.1	-87.9	0	0	0	113.9	T97	T97-W99 VanDerWaalsContact C-N 3.34Å; T97-W99 PolarHBondContact O-N 3.39Å
100	W	67.9	Low	68.3	Low	136 Å²	136	78.7 Å²	78.7	52%	0.515	40%	0.402	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.5	4	-179.6	64.6	85.6	0	0	0	114.3	V98 W445	V98-W100 VanDerWaalsContact C-N 3.26Å; V98-W100 HydrophobicContact CG1-CD2 4.28Å; V98-W100 HydrophobicContact CG1-CH2 4.13Å; V98-W100 HydrophobicContact CG1-CZ2 3.77Å; V98-W100 PolarHBondContact O-N 2.98Å; W100-W445 AromaticContact CH2-CD1 3.02Å; W100-W445 HydrophobicContact CH2-CG 4.06Å; W100-W445 AromaticContact CH2-NE1 3.03Å; W100-W445 AromaticContact CZ2-CD1 3.94Å; W100-W445 AromaticContact CZ3-CD1 3.38Å; W100-W445 HydrophobicContact CZ3-CD2 4.32Å; W100-W445 AromaticContact CZ3-CE2 3.79Å; W100-W445 HydrophobicContact CZ3-CG 4.07Å; W100-W445 HydrophobicContact CZ3-CZ2 4.48Å; W100-W445 AromaticContact CZ3-NE1 3.18Å
101	Y	54.6	Low	67.1	Low	174 Å²	174	81 Å²	81	68%	0.682	42%	0.419	S	S	*	.	S	Bend	trans	-95.9	127.3	179.9	-167.6	-95.1	0	0	0	111.9
102	P	52.3	Low	66.5	Low	94 Å²	94	80.6 Å²	80.6	61%	0.61	42%	0.417	S	S	*	.			trans	-82.7	134.4	-175.7	-5.9	23.6	0	0	0	114.4
103	Y	52.6	Low	66.1	Low	193 Å²	193	81.9 Å²	81.9	76%	0.757	42%	0.424	S	S	*	.	S	Bend	trans	38.8	104.5	152.7	-80.9	-93	0	0	0	120.6
104	N	45.7	Very low	65.8	Low	157 Å²	157	86 Å²	86	84%	0.84	44%	0.442	S	S	*	.	S	Bend	trans	-165.9	-11.3	138.8	-91.2	-18.9	0	0	0	112.8
105	H	53.9	Low	65.3	Low	169 Å²	169	93 Å²	93	78%	0.782	47%	0.474	S	S	*	.	S	Bend	trans	-129	156.5	168.5	-73.4	-59.6	0	0	0	108.7	A107	H105-A107 PolarHBondContact O-N 3.49Å
106	P	50.3	Low	65.1	Low	130 Å²	130	94 Å²	94	84%	0.844	48%	0.48	S	S	*	.			trans	-51.7	111.7	-171.5	19.8	-32.1	0	0	0	110	S108	P106-S108 PolarHBondContact O-N 2.97Å
107	A	49.9	Very low	65.2	Low	52 Å²	52	92.7 Å²	92.7	43%	0.43	48%	0.475	S	S	.	.			trans	-60.3	122.7	-176.9	0	0	0	0	0	108	H105 C109	H105-A107 PolarHBondContact O-N 3.49Å; A107-C109 VanDerWaalsContact C-N 3.33Å; A107-C109 PolarHBondContact O-N 3.3Å
108	S	54.8	Low	65.9	Low	35 Å²	35	93.8 Å²	93.8	25%	0.245	48%	0.48	C	S	.	.			trans	-66.5	101.3	166.4	34.5	0	0	0	0	106.4	T97 P106 T110	T97-S108 WeakPolarHBondContact CB-OG 3.48Å; P106-S108 PolarHBondContact O-N 2.97Å; S108-T110 PolarHBondContact O-N 2.89Å
109	C	59.4	Low	66.9	Low	130 Å²	130	96.4 Å²	96.4	88%	0.878	48%	0.482	S	S	*	.	S	Bend	trans	-64	2.6	173.8	-62	0	0	0	0	112.4	A107	A107-C109 VanDerWaalsContact C-N 3.33Å; A107-C109 PolarHBondContact O-N 3.3Å
110	T	64.2	Low	68	Low	62 Å²	62	92.7 Å²	92.7	38%	0.38	47%	0.47	S	S	.	.	S	Bend	trans	-126.6	142.1	-177.4	55.1	0	0	0	0	110.2	T97 S108 L112 F114	T97-T110 PolarHBondContact OG1-O 2.84Å; S108-T110 PolarHBondContact O-N 2.89Å; T110-L112 PolarHBondContact O-N 3.5Å; T110-L112 PolarHBondContact OG1-O 2.84Å; T110-F114 HydrophobicContact CG2-CD2 4.02Å; T110-F114 HydrophobicContact CG2-CE2 4.01Å
111	S	69.5	Low	69.1	Low	50 Å²	50	86.3 Å²	86.3	35%	0.35	45%	0.446	S	S	.	.	S	Bend	trans	-67.7	-13.6	179.2	59	0	0	0	0	114.7	T97	T97-S111 PolarHBondContact N-O 3.3Å; T97-S111 WeakPolarHBondContact OG1-CA 2.92Å; T97-S111 PolarHBondContact OG1-O 2.9Å
112	L	77.8	Confident	70.8	Confident	6 Å²	6	79 Å²	79	3%	0.031	42%	0.422	C	S	.	.	B	Isolated β-bridge	trans	-129.6	148.2	176.3	-61.9	176.9	0	0	0	110.7	I92 Y95 T110 F114	I92-L112 HydrophobicContact CB-CD2 4.29Å; I92-L112 HydrophobicContact CG1-CD1 4.03Å; I92-L112 HydrophobicContact CG1-CD2 4.09Å; I92-L112 HydrophobicContact CG2-CD2 4.41Å; Y95-L112 WeakPolarHBondContact O-CA 3.4Å; T110-L112 PolarHBondContact O-N 3.5Å; T110-L112 PolarHBondContact OG1-O 2.84Å; L112-F114 VanDerWaalsContact C-N 3.27Å; L112-F114 HydrophobicContact CB-CD1 4.42Å; L112-F114 HydrophobicContact CB-CD2 4.47Å; L112-F114 HydrophobicContact CB-CE1 4.11Å; L112-F114 HydrophobicContact CB-CE2 4.19Å; L112-F114 HydrophobicContact CB-CZ 3.99Å; L112-F114 HydrophobicContact CD1-CE1 4.1Å; L112-F114 HydrophobicContact CD1-CZ 4.24Å; L112-F114 WeakPolarHBondContact O-CD2 3.47Å; L112-F114 PolarHBondContact O-N 2.83Å
113	N	80.6	Confident	72.7	Confident	30 Å²	30	76.2 Å²	76.2	16%	0.16	41%	0.407	C	S	.	.			trans	-78.3	74.5	170.6	-79.7	-32.5	0	0	0	110.7	Y95 T97 H115 L116	Y95-N113 PolarHBondContact O-N 2.8Å; T97-N113 HydrophobicContact CG2-CB 4.12Å; T97-N113 WeakPolarHBondContact CG2-ND2 3.32Å; T97-N113 WeakPolarHBondContact CG2-OD1 3.49Å; N113-H115 PolarHBondContact O-N 2.87Å; N113-H115 VanDerWaalsContact O-N 3.11Å; N113-H115 PolarHBondContact OD1-CE1 2.67Å; N113-L116 HydrophobicContact CB-CB 4.15Å; N113-L116 HydrophobicContact CB-CD1 3.56Å; N113-L116 HydrophobicContact CB-CG 4.33Å; N113-L116 WeakPolarHBondContact O-CB 3.19Å; N113-L116 PolarHBondContact O-N 3.41Å
114	F	79.8	Confident	74.7	Confident	90 Å²	90	67.9 Å²	67.9	40%	0.395	38%	0.375	S	S	.	.	G	3₁₀ helix	trans	-58.1	-27.3	-178.1	-66.9	-69.5	0	0	0	114	T110 L112 L116 I117 Y119	T110-F114 HydrophobicContact CG2-CD2 4.02Å; T110-F114 HydrophobicContact CG2-CE2 4.01Å; L112-F114 VanDerWaalsContact C-N 3.27Å; L112-F114 HydrophobicContact CB-CD1 4.42Å; L112-F114 HydrophobicContact CB-CD2 4.47Å; L112-F114 HydrophobicContact CB-CE1 4.11Å; L112-F114 HydrophobicContact CB-CE2 4.19Å; L112-F114 HydrophobicContact CB-CZ 3.99Å; L112-F114 HydrophobicContact CD1-CE1 4.1Å; L112-F114 HydrophobicContact CD1-CZ 4.24Å; L112-F114 WeakPolarHBondContact O-CD2 3.47Å; L112-F114 PolarHBondContact O-N 2.83Å; F114-L116 PolarHBondContact O-N 3.01Å; F114-I117 HydrophobicContact CD1-CD1 4.11Å; F114-I117 PolarHBondContact O-N 3.48Å; F114-Y119 PolarHBondContact O-OH 3.45Å; F114-Y119 VanDerWaalsContact O-OH 3.1Å
115	H	78.5	Confident	76.9	Confident	147 Å²	147	60.4 Å²	60.4	68%	0.681	34%	0.335	S	S	*	.	G	3₁₀ helix	trans	-70.4	-19.3	177.3	68.4	-85.3	0	0	0	113.7	N113	N113-H115 PolarHBondContact O-N 2.87Å; N113-H115 VanDerWaalsContact O-N 3.11Å; N113-H115 PolarHBondContact OD1-CE1 2.67Å
116	L	82.2	Confident	78.8	Confident	29 Å²	29	54.6 Å²	54.6	15%	0.152	31%	0.311	C	S	.	.	G	3₁₀ helix	trans	-90.4	-13.8	178.6	-83.8	155.4	0	0	0	112.5	Y95 N113 F114 K308	Y95-L116 HydrophobicContact CD1-CB 3.57Å; Y95-L116 HydrophobicContact CE1-CB 3.62Å; Y95-L116 VanDerWaalsContact CE1-O 3.27Å; Y95-L116 WeakPolarHBondContact CE1-O 3.31Å; Y95-L116 PolarHBondContact OH-O 3.15Å; N113-L116 HydrophobicContact CB-CB 4.15Å; N113-L116 HydrophobicContact CB-CD1 3.56Å; N113-L116 HydrophobicContact CB-CG 4.33Å; N113-L116 WeakPolarHBondContact O-CB 3.19Å; N113-L116 PolarHBondContact O-N 3.41Å; F114-L116 PolarHBondContact O-N 3.01Å; L116-K308 HydrophobicContact CD2-CD 4.01Å
117	I	84.8	Confident	80.7	Confident	22 Å²	22	49.4 Å²	49.4	11%	0.113	28%	0.277	C	S	.	.	S	Bend	trans	-79.1	125.8	179.5	-61.5	177.9	0	0	0	109.1	Y91 Y95 F114 Y119	Y91-I117 HydrophobicContact CD1-CD1 4.27Å; Y91-I117 HydrophobicContact CD1-CG1 4.22Å; Y91-I117 HydrophobicContact CD1-CG2 4.02Å; Y91-I117 HydrophobicContact CE1-CG2 3.8Å; Y95-I117 HydrophobicContact CD1-CG1 4.31Å; Y95-I117 HydrophobicContact CD2-CD1 4.27Å; Y95-I117 HydrophobicContact CD2-CG1 3.67Å; Y95-I117 HydrophobicContact CE2-CG1 3.92Å; Y95-I117 HydrophobicContact CG-CG1 3.85Å; F114-I117 HydrophobicContact CD1-CD1 4.11Å; F114-I117 PolarHBondContact O-N 3.48Å; I117-Y119 PolarHBondContact O-N 3.18Å
118	D	88.3	Confident	82.6	Confident	31 Å²	31	48.2 Å²	48.2	17%	0.166	26%	0.263	C	S	.	.			trans	-79.3	105.6	170.1	-172.2	-27.9	0	0	0	110	H120 L121 A122 H181	D118-H120 VanDerWaalsContact C-N 3.29Å; D118-H120 PolarHBondContact O-N 3.37Å; D118-H120 WeakPolarHBondContact OD1-CA 3.3Å; D118-H120 WeakPolarHBondContact OD1-CB 3.2Å; D118-H120 PolarHBondContact OD1-N 2.91Å; D118-L121 HydrophobicContact CB-CB 3.94Å; D118-L121 PolarHBondContact O-N 3.29Å; D118-L121 PolarHBondContact OD1-N 2.67Å; D118-L121 VanDerWaalsContact OD1-N 3.1Å; D118-A122 PolarHBondContact O-N 2.94Å; D118-H181 IonicContact OD2-CD2 3.61Å; D118-H181 IonicContact OD2-CE1 3.76Å; D118-H181 IonicContact OD2-NE2 2.73Å; D118-H181 PolarHBondContact OD2-NE2 3.29Å
119	Y	89.9	Confident	84.3	Confident	144 Å²	144	47 Å²	47	57%	0.565	25%	0.254	S	S	*	.	H	α-helix	trans	-64.1	-31.9	178.9	-61.9	-79.7	0	0	0	113	F114 I117 A123	F114-Y119 PolarHBondContact O-OH 3.45Å; F114-Y119 VanDerWaalsContact O-OH 3.1Å; I117-Y119 PolarHBondContact O-N 3.18Å; Y119-A123 VanDerWaalsContact O-CB 3.24Å; Y119-A123 WeakPolarHBondContact O-CB 3.44Å; Y119-A123 PolarHBondContact O-N 3.49Å
120	H	90.9	Very high	85.7	Confident	65 Å²	65	41.5 Å²	41.5	30%	0.301	22%	0.218	S	C	.	.	H	α-helix	trans	-70.9	-38.3	178.7	-58.8	-52.8	0	0	0	110.7	D118 F124 N176 L177	D118-H120 VanDerWaalsContact C-N 3.29Å; D118-H120 PolarHBondContact O-N 3.37Å; D118-H120 WeakPolarHBondContact OD1-CA 3.3Å; D118-H120 WeakPolarHBondContact OD1-CB 3.2Å; D118-H120 PolarHBondContact OD1-N 2.91Å; H120-F124 WeakPolarHBondContact O-CB 3.48Å; H120-F124 PolarHBondContact O-N 3.34Å; H120-N176 HydrophobicContact CB-CB 4.41Å; H120-N176 PolarHBondContact CE1-ND2 2.96Å; H120-L177 HydrophobicContact CB-CD1 3.3Å
121	L	90.9	Very high	86.8	Confident	2 Å²	2	39.7 Å²	39.7	1%	0.01	20%	0.204	C	C	.	.	H	α-helix	trans	-66.5	-46.9	175.3	179.3	67.4	0	0	0	111.2	D118 A123 F124 I125 L177 L302 F306	D118-L121 HydrophobicContact CB-CB 3.94Å; D118-L121 PolarHBondContact O-N 3.29Å; D118-L121 PolarHBondContact OD1-N 2.67Å; D118-L121 VanDerWaalsContact OD1-N 3.1Å; L121-A123 VanDerWaalsContact C-N 3.31Å; L121-A123 PolarHBondContact O-N 3.49Å; L121-F124 PolarHBondContact O-N 2.94Å; L121-I125 HydrophobicContact CD1-CD1 4.14Å; L121-I125 HydrophobicContact CD1-CG1 4.37Å; L121-I125 HydrophobicContact CG-CD1 3.92Å; L121-I125 WeakPolarHBondContact O-CG1 3.43Å; L121-I125 PolarHBondContact O-N 3.5Å; L121-L177 HydrophobicContact CD1-CD2 4.01Å; L121-L302 HydrophobicContact CD1-CD2 4.41Å; L121-L302 HydrophobicContact CD1-CG 4.42Å; L121-F306 HydrophobicContact CD1-CD1 4.45Å; L121-F306 HydrophobicContact CD1-CD2 4.01Å; L121-F306 HydrophobicContact CD1-CE1 4.49Å; L121-F306 HydrophobicContact CD1-CE2 4.07Å; L121-F306 HydrophobicContact CD1-CG 4.23Å; L121-F306 HydrophobicContact CD1-CZ 4.32Å; L121-F306 HydrophobicContact CD2-CB 3.38Å; L121-F306 HydrophobicContact CD2-CD1 4.07Å; L121-F306 HydrophobicContact CD2-CD2 3.82Å; L121-F306 HydrophobicContact CD2-CG 3.48Å; L121-F306 VanDerWaalsContact CD2-CG 3.48Å; L121-F306 HydrophobicContact CG-CG 4.46Å
122	A	91.6	Very high	87.4	Confident	22 Å²	22	37.7 Å²	37.7	18%	0.182	19%	0.189	C	C	.	.	H	α-helix	trans	-60.5	-41.7	178.5	0	0	0	0	0	111.7	Y91 D118 T126	Y91-A122 HydrophobicContact CE2-CB 4.29Å; Y91-A122 WeakPolarHBondContact OH-CA 3.41Å; Y91-A122 WeakPolarHBondContact OH-CB 3.48Å; D118-A122 PolarHBondContact O-N 2.94Å; A122-T126 WeakPolarHBondContact O-CB 3.4Å; A122-T126 PolarHBondContact O-N 3.27Å; A122-T126 PolarHBondContact O-OG1 3.34Å
123	A	92.1	Very high	87.8	Confident	35 Å²	35	38.4 Å²	38.4	29%	0.289	19%	0.192	S	C	.	.	H	α-helix	trans	-65	-44.1	174.9	0	0	0	0	0	111.9	Y119 L121 I125 T126 V127 T173	Y119-A123 VanDerWaalsContact O-CB 3.24Å; Y119-A123 WeakPolarHBondContact O-CB 3.44Å; Y119-A123 PolarHBondContact O-N 3.49Å; L121-A123 VanDerWaalsContact C-N 3.31Å; L121-A123 PolarHBondContact O-N 3.49Å; A123-I125 PolarHBondContact O-N 3.37Å; A123-T126 PolarHBondContact O-N 3.42Å; A123-V127 WeakPolarHBondContact O-CG2 3.33Å; A123-V127 PolarHBondContact O-N 3.15Å; A123-T173 HydrophobicContact CB-CG2 3.7Å
124	F	92.8	Very high	88.1	Confident	17 Å²	17	38 Å²	38	8%	0.075	19%	0.191	C	C	.	.	H	α-helix	trans	-58.4	-49.1	175.9	175.7	-97.2	0	0	0	111.9	H120 L121 T126 V127 M128 L170 L189 Y298	H120-F124 WeakPolarHBondContact O-CB 3.48Å; H120-F124 PolarHBondContact O-N 3.34Å; L121-F124 PolarHBondContact O-N 2.94Å; F124-T126 VanDerWaalsContact C-N 3.35Å; F124-T126 PolarHBondContact O-N 2.96Å; F124-V127 PolarHBondContact O-N 3.17Å; F124-M128 HydrophobicContact CD1-CG 4.41Å; F124-M128 HydrophobicContact CE1-CG 3.94Å; F124-M128 HydrophobicContact CE2-CG 4.2Å; F124-M128 HydrophobicContact CZ-CG 3.81Å; F124-M128 HydrophobicContact CZ-SD 4.42Å; F124-M128 WeakPolarHBondContact O-CG 3.44Å; F124-M128 PolarHBondContact O-N 3.26Å; F124-L170 HydrophobicContact CD2-CD2 3.81Å; F124-L170 HydrophobicContact CE2-CD2 3.98Å; F124-L189 HydrophobicContact CD1-CD2 3.69Å; F124-L189 HydrophobicContact CD1-CG 4.01Å; F124-L189 HydrophobicContact CD2-CD2 4.27Å; F124-L189 HydrophobicContact CE1-CB 4.14Å; F124-L189 HydrophobicContact CE1-CD2 3.3Å; F124-L189 HydrophobicContact CE1-CG 3.42Å; F124-L189 VanDerWaalsContact CE1-CG 3.42Å; F124-L189 HydrophobicContact CE2-CD2 3.95Å; F124-L189 HydrophobicContact CG-CD2 4.16Å; F124-L189 HydrophobicContact CZ-CB 4.29Å; F124-L189 HydrophobicContact CZ-CD2 3.46Å; F124-L189 VanDerWaalsContact CZ-CD2 3.46Å; F124-L189 HydrophobicContact CZ-CG 3.92Å; F124-Y298 HydrophobicContact CD1-CE1 4.43Å; F124-Y298 AromaticContact CE1-CE1 3.67Å; F124-Y298 HydrophobicContact CE1-CE1 3.67Å; F124-Y298 HydrophobicContact CZ-CE1 4.39Å
125	I	92.9	Very high	88.2	Confident	0 Å²	0	37.5 Å²	37.5	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-58.4	-49.4	176.4	-66.8	168.2	0	0	0	109.7	L87 L121 A123 V127 M128 L129 Y298 L302 P303	L87-I125 HydrophobicContact CD1-CD1 4.32Å; L87-I125 HydrophobicContact CD1-CG2 3.86Å; L87-I125 HydrophobicContact CD2-CB 4.38Å; L87-I125 HydrophobicContact CD2-CG2 3.73Å; L87-I125 HydrophobicContact CG-CG2 4.44Å; L121-I125 HydrophobicContact CD1-CD1 4.14Å; L121-I125 HydrophobicContact CD1-CG1 4.37Å; L121-I125 HydrophobicContact CG-CD1 3.92Å; L121-I125 WeakPolarHBondContact O-CG1 3.43Å; L121-I125 PolarHBondContact O-N 3.5Å; A123-I125 PolarHBondContact O-N 3.37Å; I125-V127 VanDerWaalsContact C-N 3.32Å; I125-V127 PolarHBondContact O-N 3.03Å; I125-M128 WeakPolarHBondContact O-CB 3.28Å; I125-M128 PolarHBondContact O-N 2.96Å; I125-M128 VanDerWaalsContact O-N 3.09Å; I125-L129 HydrophobicContact CG2-CD1 3.77Å; I125-L129 HydrophobicContact CG2-CG 4.09Å; I125-L129 VanDerWaalsContact O-CG 3.27Å; I125-L129 WeakPolarHBondContact O-CG 3.36Å; I125-L129 PolarHBondContact O-N 3.46Å; I125-Y298 HydrophobicContact CG1-CD1 4.38Å; I125-Y298 WeakPolarHBondContact CG2-O 3.45Å; I125-L302 HydrophobicContact CD1-CD2 4.19Å; I125-L302 HydrophobicContact CD1-CG 4.43Å; I125-L302 HydrophobicContact CG1-CD2 3.9Å; I125-P303 HydrophobicContact CD1-CG 4Å
126	T	92.9	Very high	88.2	Confident	47 Å²	47	30.7 Å²	30.7	29%	0.288	16%	0.156	S	C	.	.	H	α-helix	trans	-57.2	-44.2	-178.6	-61.1	0	0	0	0	112.1	F80 L84 A122 A123 F124 L129 A130	F80-T126 HydrophobicContact CZ-CG2 4.25Å; L84-T126 HydrophobicContact CD2-CG2 3.97Å; A122-T126 WeakPolarHBondContact O-CB 3.4Å; A122-T126 PolarHBondContact O-N 3.27Å; A122-T126 PolarHBondContact O-OG1 3.34Å; A123-T126 PolarHBondContact O-N 3.42Å; F124-T126 VanDerWaalsContact C-N 3.35Å; F124-T126 PolarHBondContact O-N 2.96Å; T126-L129 PolarHBondContact O-N 3.18Å; T126-A130 WeakPolarHBondContact O-CB 3.19Å; T126-A130 PolarHBondContact O-N 2.86Å
127	V	91.1	Very high	88.2	Confident	22 Å²	22	32.6 Å²	32.6	13%	0.133	17%	0.165	C	C	.	.	H	α-helix	trans	-69.3	-36.5	177.9	-177	0	0	0	0	111.7	A123 F124 I125 L129 A130 R131 C166 V169 L170	A123-V127 WeakPolarHBondContact O-CG2 3.33Å; A123-V127 PolarHBondContact O-N 3.15Å; F124-V127 PolarHBondContact O-N 3.17Å; I125-V127 VanDerWaalsContact C-N 3.32Å; I125-V127 PolarHBondContact O-N 3.03Å; V127-L129 VanDerWaalsContact C-N 3.34Å; V127-L129 PolarHBondContact O-N 3.44Å; V127-A130 PolarHBondContact O-N 3.15Å; V127-R131 PolarHBondContact O-N 3.13Å; V127-C166 HydrophobicContact CG1-CB 4.11Å; V127-V169 HydrophobicContact CG2-CB 4.41Å; V127-V169 HydrophobicContact CG2-CG1 3.79Å; V127-L170 HydrophobicContact CB-CD2 3.69Å; V127-L170 HydrophobicContact CB-CG 4.06Å; V127-L170 HydrophobicContact CG1-CD1 3.79Å; V127-L170 HydrophobicContact CG1-CD2 3.64Å; V127-L170 HydrophobicContact CG1-CG 3.48Å; V127-L170 VanDerWaalsContact CG1-CG 3.48Å
128	M	89.1	Confident	87.8	Confident	26 Å²	26	32.8 Å²	32.8	13%	0.128	17%	0.167	C	C	.	.	H	α-helix	trans	-62.9	-38.5	173.4	-76.8	-66.3	102.4	0	0	113	F124 I125 R131 L170 Y298	F124-M128 HydrophobicContact CD1-CG 4.41Å; F124-M128 HydrophobicContact CE1-CG 3.94Å; F124-M128 HydrophobicContact CE2-CG 4.2Å; F124-M128 HydrophobicContact CZ-CG 3.81Å; F124-M128 HydrophobicContact CZ-SD 4.42Å; F124-M128 WeakPolarHBondContact O-CG 3.44Å; F124-M128 PolarHBondContact O-N 3.26Å; I125-M128 WeakPolarHBondContact O-CB 3.28Å; I125-M128 PolarHBondContact O-N 2.96Å; I125-M128 VanDerWaalsContact O-N 3.09Å; M128-R131 WeakPolarHBondContact O-CB 2.92Å; M128-R131 VanDerWaalsContact O-CD 3.29Å; M128-R131 WeakPolarHBondContact O-CD 3.42Å; M128-R131 WeakPolarHBondContact O-CG 3.08Å; M128-L170 HydrophobicContact CE-CD1 3.35Å; M128-L170 HydrophobicContact CE-CD2 3.39Å; M128-L170 HydrophobicContact CE-CG 4Å; M128-L170 HydrophobicContact CG-CD2 4.38Å; M128-Y298 HydrophobicContact CB-CD1 4.01Å; M128-Y298 HydrophobicContact CB-CE1 3.89Å; M128-Y298 HydrophobicContact CG-CD1 4.37Å; M128-Y298 HydrophobicContact CG-CE1 3.77Å
129	L	90.3	Very high	87.1	Confident	11 Å²	11	33.1 Å²	33.1	6%	0.058	17%	0.171	C	C	.	.	H	α-helix	trans	-71.3	-36	174.8	-61.9	178.2	0	0	0	111.8	F80 L83 L87 I125 T126 V127 R131 V299	F80-L129 HydrophobicContact CD2-CB 4.24Å; F80-L129 HydrophobicContact CE2-CB 4.08Å; L83-L129 HydrophobicContact CB-CD1 4.09Å; L83-L129 HydrophobicContact CD1-CD2 4.13Å; L87-L129 HydrophobicContact CD2-CD1 4.38Å; I125-L129 HydrophobicContact CG2-CD1 3.77Å; I125-L129 HydrophobicContact CG2-CG 4.09Å; I125-L129 VanDerWaalsContact O-CG 3.27Å; I125-L129 WeakPolarHBondContact O-CG 3.36Å; I125-L129 PolarHBondContact O-N 3.46Å; T126-L129 PolarHBondContact O-N 3.18Å; V127-L129 VanDerWaalsContact C-N 3.34Å; V127-L129 PolarHBondContact O-N 3.44Å; L129-R131 PolarHBondContact O-N 3.42Å; L129-V299 HydrophobicContact CD1-CG2 3.71Å; L129-V299 HydrophobicContact CD2-CG2 4.08Å
130	A	89.3	Confident	86.4	Confident	14 Å²	14	29.5 Å²	29.5	12%	0.116	16%	0.16	C	C	.	.	H	α-helix	trans	-69.5	-15.7	179.3	0	0	0	0	0	113.6	F80 T126 V127 R132 L133 V134	F80-A130 HydrophobicContact CD2-CB 4.3Å; F80-A130 HydrophobicContact CE2-CB 3.63Å; F80-A130 HydrophobicContact CZ-CB 3.89Å; T126-A130 WeakPolarHBondContact O-CB 3.19Å; T126-A130 PolarHBondContact O-N 2.86Å; V127-A130 PolarHBondContact O-N 3.15Å; A130-R132 VanDerWaalsContact C-N 3.29Å; A130-R132 PolarHBondContact O-N 3.12Å; A130-R132 VanDerWaalsContact O-N 3.17Å; A130-L133 WeakPolarHBondContact O-CB 3.34Å; A130-L133 PolarHBondContact O-N 3.3Å; A130-L133 VanDerWaalsContact O-N 3.08Å; A130-V134 HydrophobicContact CB-CG2 4.45Å; A130-V134 WeakPolarHBondContact O-CG2 3.32Å; A130-V134 PolarHBondContact O-N 2.84Å
131	R	86.8	Confident	85.2	Confident	23 Å²	23	27.2 Å²	27.2	9%	0.087	15%	0.152	C	C	.	.	H	α-helix	trans	-52.8	-41.6	-173.9	81.3	-175.7	178.9	-153.5	-2.7	114	V127 M128 L129 V134 W135 F252 F294	V127-R131 PolarHBondContact O-N 3.13Å; M128-R131 WeakPolarHBondContact O-CB 2.92Å; M128-R131 VanDerWaalsContact O-CD 3.29Å; M128-R131 WeakPolarHBondContact O-CD 3.42Å; M128-R131 WeakPolarHBondContact O-CG 3.08Å; L129-R131 PolarHBondContact O-N 3.42Å; R131-V134 PolarHBondContact O-N 3.27Å; R131-W135 WeakPolarHBondContact O-CB 3.37Å; R131-W135 PolarHBondContact O-N 3.44Å; R131-F252 HydrophobicContact CB-CE1 4.09Å; R131-F252 HydrophobicContact CG-CE1 4.38Å; R131-F294 VanDerWaalsContact NH2-CE1 3.35Å; R131-F294 VanDerWaalsContact NH2-CG 3.3Å
132	R	83.8	Confident	84.1	Confident	8 Å²	8	30.7 Å²	30.7	3%	0.03	17%	0.173	C	C	.	.	H	α-helix	trans	-71.5	-38.5	-177.7	-68.4	-178.2	71.8	-128.7	9.8	110.5	E76 F79 A130 W135 A136 N254 L333	E76-R132 IonicContact OE1-CZ 3.62Å; E76-R132 VanDerWaalsContact OE1-CZ 3.23Å; E76-R132 IonicContact OE1-NE 2.95Å; E76-R132 IonicContact OE1-NH1 3.02Å; E76-R132 PolarHBondContact OE1-NH1 3.41Å; E76-R132 IonicContact OE1-NH2 3.76Å; E76-R132 PolarHBondContact OE1-NH2 3.21Å; E76-R132 WeakPolarHBondContact OE2-CB 3.17Å; E76-R132 IonicContact OE2-CZ 3.81Å; E76-R132 IonicContact OE2-NE 3.75Å; E76-R132 IonicContact OE2-NH1 3.9Å; E76-R132 PolarHBondContact OE2-NH1 3.17Å; E76-R132 IonicContact OE2-NH2 3.46Å; F79-R132 VanDerWaalsContact CD1-NH1 3.26Å; F79-R132 VanDerWaalsContact CE1-NH1 3.26Å; A130-R132 VanDerWaalsContact C-N 3.29Å; A130-R132 PolarHBondContact O-N 3.12Å; A130-R132 VanDerWaalsContact O-N 3.17Å; R132-W135 PolarHBondContact O-N 3.47Å; R132-A136 WeakPolarHBondContact O-CB 3.43Å; R132-A136 PolarHBondContact O-N 3.16Å; R132-N254 PolarHBondContact NH2-OD1 3.33Å; R132-L333 VanDerWaalsContact CZ-CD2 3.47Å; R132-L333 VanDerWaalsContact NH1-CD2 3.29Å
133	L	86.3	Confident	82.9	Confident	21 Å²	21	36.5 Å²	36.5	11%	0.11	19%	0.194	C	C	.	.	H	α-helix	trans	-65.1	-45.9	173.3	178.1	61.6	0	0	0	111.6	E76 F77 F80 A130 W135 A136 L137	E76-L133 HydrophobicContact CB-CD1 4.1Å; F77-L133 HydrophobicContact CB-CD1 4.12Å; F77-L133 HydrophobicContact CD2-CD2 4.36Å; F80-L133 HydrophobicContact CB-CD2 4.08Å; F80-L133 HydrophobicContact CD1-CD2 3.65Å; F80-L133 HydrophobicContact CE1-CD2 4.29Å; F80-L133 HydrophobicContact CG-CD2 3.95Å; A130-L133 WeakPolarHBondContact O-CB 3.34Å; A130-L133 PolarHBondContact O-N 3.3Å; A130-L133 VanDerWaalsContact O-N 3.08Å; L133-W135 VanDerWaalsContact C-N 3.3Å; L133-W135 PolarHBondContact O-N 2.94Å; L133-A136 PolarHBondContact O-N 3.42Å; L133-L137 HydrophobicContact CD1-CD1 4.37Å; L133-L137 HydrophobicContact CD1-CG 4.44Å; L133-L137 HydrophobicContact CG-CD1 4.11Å; L133-L137 WeakPolarHBondContact O-CB 3.44Å; L133-L137 WeakPolarHBondContact O-CG 3.43Å; L133-L137 PolarHBondContact O-N 3.41Å
134	V	85.1	Confident	81.5	Confident	21 Å²	21	37.5 Å²	37.5	13%	0.127	20%	0.203	C	C	.	.	H	α-helix	trans	-58.9	-43.5	176.4	172.8	0	0	0	0	110.4	A130 R131 L137 I138 L162	A130-V134 HydrophobicContact CB-CG2 4.45Å; A130-V134 WeakPolarHBondContact O-CG2 3.32Å; A130-V134 PolarHBondContact O-N 2.84Å; R131-V134 PolarHBondContact O-N 3.27Å; V134-L137 WeakPolarHBondContact O-CB 3.41Å; V134-L137 PolarHBondContact O-N 2.93Å; V134-I138 HydrophobicContact CG1-CD1 3.9Å; V134-I138 WeakPolarHBondContact O-CD1 3.47Å; V134-I138 VanDerWaalsContact O-CG1 3.24Å; V134-I138 WeakPolarHBondContact O-CG1 3.25Å; V134-I138 PolarHBondContact O-N 3.48Å; V134-L162 HydrophobicContact CG1-CD2 4.05Å; V134-L162 HydrophobicContact CG1-CG 4.24Å; V134-L162 HydrophobicContact CG2-CD2 4.39Å
135	W	81.7	Confident	79.7	Confident	80 Å²	80	38 Å²	38	30%	0.303	21%	0.213	S	C	.	.	H	α-helix	trans	-66.6	-41.5	175.8	-174.5	-96.4	0	0	0	113.4	R131 R132 L133 L137 I138 S139 F252 N253	R131-W135 WeakPolarHBondContact O-CB 3.37Å; R131-W135 PolarHBondContact O-N 3.44Å; R132-W135 PolarHBondContact O-N 3.47Å; L133-W135 VanDerWaalsContact C-N 3.3Å; L133-W135 PolarHBondContact O-N 2.94Å; W135-L137 VanDerWaalsContact C-N 3.31Å; W135-L137 PolarHBondContact O-N 3.33Å; W135-I138 PolarHBondContact O-N 3.23Å; W135-S139 WeakPolarHBondContact O-CB 3.31Å; W135-S139 PolarHBondContact O-N 3.39Å; W135-S139 PolarHBondContact O-OG 3.01Å; W135-F252 HydrophobicContact CB-CD1 4.12Å; W135-F252 HydrophobicContact CD2-CB 3.73Å; W135-F252 HydrophobicContact CD2-CD1 4.36Å; W135-F252 HydrophobicContact CD2-CG 4.38Å; W135-F252 HydrophobicContact CE3-CB 4.01Å; W135-F252 HydrophobicContact CE3-CD1 4.22Å; W135-F252 HydrophobicContact CE3-CG 4.25Å; W135-F252 HydrophobicContact CG-CB 4.01Å; W135-F252 HydrophobicContact CG-CD1 4.35Å; W135-F252 HydrophobicContact CZ2-CB 4.37Å; W135-F252 HydrophobicContact CZ3-CB 4.44Å; W135-F252 PolarHBondContact NE1-O 3.13Å; W135-N253 VanDerWaalsContact CZ2-OD1 3.3Å; W135-N253 WeakPolarHBondContact CZ2-OD1 3.39Å; W135-N253 PolarHBondContact NE1-OD1 3.24Å
136	A	79.9	Confident	78	Confident	4 Å²	4	43 Å²	43	3%	0.033	25%	0.254	C	S	.	.	H	α-helix	trans	-60.5	-41.4	174.9	0	0	0	0	0	111.7	E76 R132 L133 S139 E140	E76-A136 HydrophobicContact CB-CB 4.13Å; E76-A136 HydrophobicContact CG-CB 3.82Å; R132-A136 WeakPolarHBondContact O-CB 3.43Å; R132-A136 PolarHBondContact O-N 3.16Å; L133-A136 PolarHBondContact O-N 3.42Å; A136-S139 WeakPolarHBondContact CA-OG 3.43Å; A136-S139 PolarHBondContact O-N 2.9Å; A136-S139 PolarHBondContact O-OG 3.33Å; A136-S139 VanDerWaalsContact O-OG 3.06Å; A136-E140 VanDerWaalsContact O-CB 3.29Å; A136-E140 WeakPolarHBondContact O-CB 3.41Å; A136-E140 PolarHBondContact O-N 2.98Å
137	L	81	Confident	76.6	Confident	69 Å²	69	45.1 Å²	45.1	36%	0.361	28%	0.276	S	S	.	.	H	α-helix	trans	-60.7	-44	173.5	-74.7	163.9	0	0	0	112.1	L73 L133 V134 W135 A141 L162	L73-L137 HydrophobicContact CD1-CD2 3.53Å; L73-L137 HydrophobicContact CD1-CG 4.29Å; L73-L137 HydrophobicContact CG-CD2 4.26Å; L133-L137 HydrophobicContact CD1-CD1 4.37Å; L133-L137 HydrophobicContact CD1-CG 4.44Å; L133-L137 HydrophobicContact CG-CD1 4.11Å; L133-L137 WeakPolarHBondContact O-CB 3.44Å; L133-L137 WeakPolarHBondContact O-CG 3.43Å; L133-L137 PolarHBondContact O-N 3.41Å; V134-L137 WeakPolarHBondContact O-CB 3.41Å; V134-L137 PolarHBondContact O-N 2.93Å; W135-L137 VanDerWaalsContact C-N 3.31Å; W135-L137 PolarHBondContact O-N 3.33Å; L137-A141 VanDerWaalsContact O-CB 3.23Å; L137-A141 WeakPolarHBondContact O-CB 3.36Å; L137-A141 PolarHBondContact O-N 3.25Å; L137-L162 HydrophobicContact CD1-CD2 4.37Å
138	I	76.9	Confident	75.7	Confident	27 Å²	27	46.9 Å²	46.9	14%	0.138	29%	0.29	C	S	.	.	H	α-helix	trans	-63.7	-45.5	177.6	-70.3	164.7	0	0	0	111.1	V134 W135 T142 R159 L163	V134-I138 HydrophobicContact CG1-CD1 3.9Å; V134-I138 WeakPolarHBondContact O-CD1 3.47Å; V134-I138 VanDerWaalsContact O-CG1 3.24Å; V134-I138 WeakPolarHBondContact O-CG1 3.25Å; V134-I138 PolarHBondContact O-N 3.48Å; W135-I138 PolarHBondContact O-N 3.23Å; I138-T142 PolarHBondContact O-N 2.8Å; I138-T142 PolarHBondContact O-OG1 2.95Å; I138-R159 HydrophobicContact CG1-CB 4.31Å; I138-R159 HydrophobicContact CG1-CG 4.05Å; I138-R159 PolarHBondContact O-NH1 3.42Å; I138-L163 HydrophobicContact CD1-CD1 4.13Å
139	S	73.8	Confident	75.1	Confident	37 Å²	37	53 Å²	53	26%	0.259	32%	0.32	S	S	.	.	H	α-helix	trans	-73.2	-41.6	-175.2	59	0	0	0	0	113	W135 A136 T142	W135-S139 WeakPolarHBondContact O-CB 3.31Å; W135-S139 PolarHBondContact O-N 3.39Å; W135-S139 PolarHBondContact O-OG 3.01Å; A136-S139 WeakPolarHBondContact CA-OG 3.43Å; A136-S139 PolarHBondContact O-N 2.9Å; A136-S139 PolarHBondContact O-OG 3.33Å; A136-S139 VanDerWaalsContact O-OG 3.06Å; S139-T142 WeakPolarHBondContact O-CB 3.26Å; S139-T142 PolarHBondContact O-N 2.99Å
140	E	74.6	Confident	74.4	Confident	69 Å²	69	58.9 Å²	58.9	32%	0.322	35%	0.35	S	S	.	.	H	α-helix	trans	-67.9	-41.9	179.5	-164.2	59.5	-149.2	0	0	111.5	S72 L73 A136 T142 K143 A144	S72-E140 PolarHBondContact OG-OE2 3.33Å; L73-E140 HydrophobicContact CD1-CB 4.36Å; A136-E140 VanDerWaalsContact O-CB 3.29Å; A136-E140 WeakPolarHBondContact O-CB 3.41Å; A136-E140 PolarHBondContact O-N 2.98Å; E140-T142 PolarHBondContact O-N 2.94Å; E140-K143 PolarHBondContact O-N 2.76Å; E140-K143 VanDerWaalsContact O-N 3.1Å; E140-K143 IonicContact OE2-NZ 2.95Å; E140-A144 PolarHBondContact O-N 2.89Å
141	A	65.7	Low	73.8	Confident	17 Å²	17	63 Å²	63	14%	0.14	37%	0.366	C	S	.	.	H	α-helix	trans	-62.8	-26.6	175.7	0	0	0	0	0	112.2	L137 K143 L155 R159	L137-A141 VanDerWaalsContact O-CB 3.23Å; L137-A141 WeakPolarHBondContact O-CB 3.36Å; L137-A141 PolarHBondContact O-N 3.25Å; A141-K143 VanDerWaalsContact C-N 3.32Å; A141-L155 HydrophobicContact CB-CD2 4.27Å; A141-R159 PolarHBondContact O-NH2 2.93Å
142	T	68.4	Low	73.3	Confident	75 Å²	75	65.7 Å²	65.7	46%	0.46	38%	0.377	S	S	.	.	H	α-helix	trans	-69.1	-33.3	177.7	-54.6	0	0	0	0	111.3	I138 S139 E140 R159	I138-T142 PolarHBondContact O-N 2.8Å; I138-T142 PolarHBondContact O-OG1 2.95Å; S139-T142 WeakPolarHBondContact O-CB 3.26Å; S139-T142 PolarHBondContact O-N 2.99Å; E140-T142 PolarHBondContact O-N 2.94Å; T142-R159 PolarHBondContact OG1-NH1 3.42Å
143	K	66.7	Low	73.1	Confident	143 Å²	143	70.2 Å²	70.2	62%	0.622	40%	0.4	S	S	*	.	H	α-helix	trans	-76.6	-30.8	178.7	-61.8	173.1	-173.4	167.5	0	112.6	E140 A141 G145	E140-K143 PolarHBondContact O-N 2.76Å; E140-K143 VanDerWaalsContact O-N 3.1Å; E140-K143 IonicContact OE2-NZ 2.95Å; A141-K143 VanDerWaalsContact C-N 3.32Å; K143-G145 PolarHBondContact O-N 3.02Å
144	A	62.1	Low	72.9	Confident	57 Å²	57	73.3 Å²	73.3	47%	0.471	42%	0.419	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.4	1.5	179.6	0	0	0	0	0	114.7	E140 A146	E140-A144 PolarHBondContact O-N 2.89Å; A144-A146 PolarHBondContact O-N 3.42Å
145	G	55.4	Low	72.5	Confident	28 Å²	28	74.3 Å²	74.3	29%	0.289	42%	0.424	S	S	.	.	T	Hydrogen-bonded Turn	trans	-72	9.9	-168.3	0	0	0	0	0	118	K143	K143-G145 PolarHBondContact O-N 3.02Å
146	A	56.8	Low	72.4	Confident	104 Å²	104	73.8 Å²	73.8	86%	0.86	43%	0.426	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.6	-9.7	-172	0	0	0	0	0	115.7	A144	A144-A146 PolarHBondContact O-N 3.42Å
147	A	64.4	Low	72.5	Confident	91 Å²	91	76.6 Å²	76.6	75%	0.752	45%	0.446	S	S	*	.	S	Bend	trans	-91.7	-31.6	-167.5	0	0	0	0	0	115.6
148	S	71.4	Confident	72.5	Confident	60 Å²	60	76 Å²	76	42%	0.42	45%	0.45	S	S	.	.			trans	-165.7	144	171.6	64.4	0	0	0	0	113.1	I150 H151 Y152	S148-I150 VanDerWaalsContact C-N 3.3Å; S148-I150 PolarHBondContact O-N 3.4Å; S148-H151 PolarHBondContact O-N 3.3Å; S148-H151 WeakPolarHBondContact OG-CB 3.29Å; S148-H151 PolarHBondContact OG-N 3.25Å; S148-Y152 PolarHBondContact O-N 2.85Å; S148-Y152 VanDerWaalsContact O-N 3.07Å
149	M	76.6	Confident	72.6	Confident	155 Å²	155	76.1 Å²	76.1	76%	0.764	45%	0.449	S	S	*	.	H	α-helix	trans	-60.3	-36.9	-179.5	-176.9	-178.2	-94.5	0	0	112.5	Y152 M153	M149-Y152 PolarHBondContact O-N 3.46Å; M149-M153 WeakPolarHBondContact O-CG 3.2Å; M149-M153 PolarHBondContact O-N 2.9Å
150	I	76.7	Confident	73	Confident	134 Å²	134	80 Å²	80	69%	0.687	47%	0.466	S	S	*	.	H	α-helix	trans	-68.3	-45.9	179.1	-61.1	171.2	0	0	0	110.7	S148 Y152 M153 V154	S148-I150 VanDerWaalsContact C-N 3.3Å; S148-I150 PolarHBondContact O-N 3.4Å; I150-Y152 VanDerWaalsContact C-N 3.27Å; I150-Y152 PolarHBondContact O-N 3.49Å; I150-M153 PolarHBondContact O-N 3.29Å; I150-V154 HydrophobicContact CG2-CG2 4.47Å; I150-V154 WeakPolarHBondContact O-CG2 3.45Å; I150-V154 PolarHBondContact O-N 2.96Å
151	H	75.6	Confident	73.6	Confident	99 Å²	99	81 Å²	81	46%	0.458	48%	0.478	S	S	.	.	H	α-helix	trans	-62.8	-36.7	177.5	-169	-115.4	0	0	0	111.5	S148 L155	S148-H151 PolarHBondContact O-N 3.3Å; S148-H151 WeakPolarHBondContact OG-CB 3.29Å; S148-H151 PolarHBondContact OG-N 3.25Å; H151-L155 WeakPolarHBondContact O-CB 3.22Å; H151-L155 VanDerWaalsContact O-CG 3.25Å; H151-L155 WeakPolarHBondContact O-CG 3.39Å; H151-L155 PolarHBondContact O-N 3.02Å
152	Y	76.4	Confident	74.6	Confident	80 Å²	80	82.9 Å²	82.9	31%	0.314	49%	0.485	S	S	.	.	H	α-helix	trans	-63.5	-44.8	173.4	-178.7	-94.6	0	0	0	112.7	S148 M149 I150 L155 I156	S148-Y152 PolarHBondContact O-N 2.85Å; S148-Y152 VanDerWaalsContact O-N 3.07Å; M149-Y152 PolarHBondContact O-N 3.46Å; I150-Y152 VanDerWaalsContact C-N 3.27Å; I150-Y152 PolarHBondContact O-N 3.49Å; Y152-L155 PolarHBondContact O-N 3.31Å; Y152-I156 HydrophobicContact CE1-CD1 4.15Å; Y152-I156 PolarHBondContact O-N 3.28Å
153	M	80.3	Confident	75.4	Confident	103 Å²	103	84.1 Å²	84.1	51%	0.507	49%	0.488	S	S	.	.	H	α-helix	trans	-66.9	-38.4	177.6	-68.7	-58.9	155.4	0	0	112.7	M149 I150 I156 S157	M149-M153 WeakPolarHBondContact O-CG 3.2Å; M149-M153 PolarHBondContact O-N 2.9Å; I150-M153 PolarHBondContact O-N 3.29Å; M153-I156 WeakPolarHBondContact O-CG2 3.31Å; M153-I156 PolarHBondContact O-N 3.43Å; M153-I156 HydrophobicContact SD-CG2 4.32Å; M153-S157 WeakPolarHBondContact O-CB 3.39Å; M153-S157 PolarHBondContact O-N 2.65Å; M153-S157 PolarHBondContact O-OG 2.67Å
154	V	81.2	Confident	76.4	Confident	86 Å²	86	80.9 Å²	80.9	52%	0.521	48%	0.48	S	S	.	.	H	α-helix	trans	-63.4	-46.1	173.2	172.8	0	0	0	0	110.4	I150 I156 S157 A158	I150-V154 HydrophobicContact CG2-CG2 4.47Å; I150-V154 WeakPolarHBondContact O-CG2 3.45Å; I150-V154 PolarHBondContact O-N 2.96Å; V154-I156 PolarHBondContact O-N 2.84Å; V154-S157 PolarHBondContact O-N 2.94Å; V154-S157 PolarHBondContact O-OG 3.45Å; V154-A158 WeakPolarHBondContact O-CB 3.27Å; V154-A158 PolarHBondContact O-N 2.99Å
155	L	77.6	Confident	77.7	Confident	42 Å²	42	82.8 Å²	82.8	22%	0.22	48%	0.482	C	S	.	.	H	α-helix	trans	-62.7	-40.6	178	-76.3	170	0	0	0	112.7	A141 H151 Y152 R159	A141-L155 HydrophobicContact CB-CD2 4.27Å; H151-L155 WeakPolarHBondContact O-CB 3.22Å; H151-L155 VanDerWaalsContact O-CG 3.25Å; H151-L155 WeakPolarHBondContact O-CG 3.39Å; H151-L155 PolarHBondContact O-N 3.02Å; Y152-L155 PolarHBondContact O-N 3.31Å; L155-R159 VanDerWaalsContact O-CG 3.27Å; L155-R159 WeakPolarHBondContact O-CG 3.35Å; L155-R159 PolarHBondContact O-N 2.72Å; L155-R159 VanDerWaalsContact O-N 3.12Å
156	I	79.6	Confident	79.3	Confident	69 Å²	69	82.8 Å²	82.8	35%	0.354	48%	0.477	S	S	.	.	H	α-helix	trans	-71	-38.5	-179.6	-148.2	153.3	0	0	0	111.8	Y152 M153 V154 R159 L160	Y152-I156 HydrophobicContact CE1-CD1 4.15Å; Y152-I156 PolarHBondContact O-N 3.28Å; M153-I156 WeakPolarHBondContact O-CG2 3.31Å; M153-I156 PolarHBondContact O-N 3.43Å; M153-I156 HydrophobicContact SD-CG2 4.32Å; V154-I156 PolarHBondContact O-N 2.84Å; I156-R159 WeakPolarHBondContact O-CB 3.44Å; I156-R159 PolarHBondContact O-N 3.06Å; I156-L160 PolarHBondContact O-N 3.07Å
157	S	82.4	Confident	80.8	Confident	64 Å²	64	79.6 Å²	79.6	45%	0.448	46%	0.455	S	S	.	.	H	α-helix	trans	-63.8	-44.3	174.2	69.2	0	0	0	0	111.5	M153 V154 R159 L160 V161	M153-S157 WeakPolarHBondContact O-CB 3.39Å; M153-S157 PolarHBondContact O-N 2.65Å; M153-S157 PolarHBondContact O-OG 2.67Å; V154-S157 PolarHBondContact O-N 2.94Å; V154-S157 PolarHBondContact O-OG 3.45Å; S157-R159 VanDerWaalsContact C-N 3.27Å; S157-R159 PolarHBondContact O-N 3.02Å; S157-L160 PolarHBondContact O-N 3.35Å; S157-V161 VanDerWaalsContact O-CG2 3.3Å; S157-V161 WeakPolarHBondContact O-CG2 3.35Å; S157-V161 PolarHBondContact O-N 3.38Å
158	A	80.6	Confident	82.2	Confident	55 Å²	55	83.2 Å²	83.2	46%	0.455	45%	0.449	S	S	.	.	H	α-helix	trans	-59.4	-36.3	175.7	0	0	0	0	0	112.5	V154 L162	V154-A158 WeakPolarHBondContact O-CB 3.27Å; V154-A158 PolarHBondContact O-N 2.99Å; A158-L162 VanDerWaalsContact O-CB 3.32Å; A158-L162 WeakPolarHBondContact O-CB 3.34Å; A158-L162 PolarHBondContact O-N 2.92Å
159	R	77.6	Confident	83.1	Confident	30 Å²	30	82.6 Å²	82.6	11%	0.113	44%	0.442	C	S	.	.	H	α-helix	trans	-67.8	-45.2	174.9	-70.2	171.8	-150	175.2	9	113	I138 A141 T142 L155 I156 S157 V161 L162 L163	I138-R159 HydrophobicContact CG1-CB 4.31Å; I138-R159 HydrophobicContact CG1-CG 4.05Å; I138-R159 PolarHBondContact O-NH1 3.42Å; A141-R159 PolarHBondContact O-NH2 2.93Å; T142-R159 PolarHBondContact OG1-NH1 3.42Å; L155-R159 VanDerWaalsContact O-CG 3.27Å; L155-R159 WeakPolarHBondContact O-CG 3.35Å; L155-R159 PolarHBondContact O-N 2.72Å; L155-R159 VanDerWaalsContact O-N 3.12Å; I156-R159 WeakPolarHBondContact O-CB 3.44Å; I156-R159 PolarHBondContact O-N 3.06Å; S157-R159 VanDerWaalsContact C-N 3.27Å; S157-R159 PolarHBondContact O-N 3.02Å; R159-V161 VanDerWaalsContact C-N 3.28Å; R159-V161 PolarHBondContact O-N 3.49Å; R159-L162 PolarHBondContact O-N 3.05Å; R159-L163 WeakPolarHBondContact O-CB 3.42Å; R159-L163 PolarHBondContact O-N 3.28Å
160	L	82.1	Confident	83.7	Confident	118 Å²	118	77 Å²	77	62%	0.618	42%	0.415	S	S	*	.	H	α-helix	trans	-62.9	-44.2	-180	-162.3	150.6	0	0	0	109	I156 S157 L163 T164	I156-L160 PolarHBondContact O-N 3.07Å; S157-L160 PolarHBondContact O-N 3.35Å; L160-L163 PolarHBondContact O-N 3.46Å; L160-T164 HydrophobicContact CD2-CG2 3.78Å; L160-T164 WeakPolarHBondContact O-CB 3.35Å; L160-T164 VanDerWaalsContact O-CG2 3.24Å; L160-T164 WeakPolarHBondContact O-CG2 3.48Å; L160-T164 PolarHBondContact O-N 3.02Å; L160-T164 PolarHBondContact O-OG1 3.43Å
161	V	88.1	Confident	84.4	Confident	92 Å²	92	74.2 Å²	74.2	56%	0.558	41%	0.407	S	S	*	.	H	α-helix	trans	-57.4	-51.3	172.8	173.6	0	0	0	0	111.1	S157 R159 L163 T164 L165	S157-V161 VanDerWaalsContact O-CG2 3.3Å; S157-V161 WeakPolarHBondContact O-CG2 3.35Å; S157-V161 PolarHBondContact O-N 3.38Å; R159-V161 VanDerWaalsContact C-N 3.28Å; R159-V161 PolarHBondContact O-N 3.49Å; V161-L163 PolarHBondContact O-N 3.23Å; V161-T164 WeakPolarHBondContact CA-OG1 3.09Å; V161-T164 PolarHBondContact O-N 2.96Å; V161-T164 PolarHBondContact O-OG1 3.34Å; V161-L165 VanDerWaalsContact O-CB 3.26Å; V161-L165 WeakPolarHBondContact O-CB 3.45Å; V161-L165 PolarHBondContact O-N 3.46Å
162	L	86.8	Confident	85.3	Confident	56 Å²	56	76.1 Å²	76.1	29%	0.293	41%	0.41	S	S	.	.	H	α-helix	trans	-59.2	-45.6	179.9	-178.2	64.1	0	0	0	112.4	V134 L137 A158 R159 L165 C166	V134-L162 HydrophobicContact CG1-CD2 4.05Å; V134-L162 HydrophobicContact CG1-CG 4.24Å; V134-L162 HydrophobicContact CG2-CD2 4.39Å; L137-L162 HydrophobicContact CD1-CD2 4.37Å; A158-L162 VanDerWaalsContact O-CB 3.32Å; A158-L162 WeakPolarHBondContact O-CB 3.34Å; A158-L162 PolarHBondContact O-N 2.92Å; R159-L162 PolarHBondContact O-N 3.05Å; L162-L165 PolarHBondContact O-N 3.49Å; L162-C166 WeakPolarHBondContact O-CB 3.41Å; L162-C166 PolarHBondContact O-N 3.05Å; L162-C166 PolarHBondContact O-SG 2.85Å; L162-C166 VanDerWaalsContact O-SG 3.37Å
163	L	85.1	Confident	86	Confident	101 Å²	101	72.5 Å²	72.5	53%	0.529	40%	0.397	S	S	.	.	H	α-helix	trans	-67.7	-42.1	179.8	-170.9	145.7	0	0	0	111.4	I138 R159 L160 V161 L165 C166 G167	I138-L163 HydrophobicContact CD1-CD1 4.13Å; R159-L163 WeakPolarHBondContact O-CB 3.42Å; R159-L163 PolarHBondContact O-N 3.28Å; L160-L163 PolarHBondContact O-N 3.46Å; V161-L163 PolarHBondContact O-N 3.23Å; L163-L165 VanDerWaalsContact C-N 3.33Å; L163-L165 PolarHBondContact O-N 2.91Å; L163-C166 PolarHBondContact O-N 2.99Å; L163-G167 PolarHBondContact O-N 3.36Å
164	T	87.7	Confident	86.4	Confident	74 Å²	74	70.6 Å²	70.6	45%	0.454	39%	0.388	S	S	.	.	H	α-helix	trans	-64	-38.3	174.4	57.5	0	0	0	0	111.9	L160 V161 G167 W168	L160-T164 HydrophobicContact CD2-CG2 3.78Å; L160-T164 WeakPolarHBondContact O-CB 3.35Å; L160-T164 VanDerWaalsContact O-CG2 3.24Å; L160-T164 WeakPolarHBondContact O-CG2 3.48Å; L160-T164 PolarHBondContact O-N 3.02Å; L160-T164 PolarHBondContact O-OG1 3.43Å; V161-T164 WeakPolarHBondContact CA-OG1 3.09Å; V161-T164 PolarHBondContact O-N 2.96Å; V161-T164 PolarHBondContact O-OG1 3.34Å; T164-G167 PolarHBondContact O-N 3.49Å; T164-W168 WeakPolarHBondContact O-CB 3.49Å; T164-W168 PolarHBondContact O-N 3.37Å
165	L	90	Very high	86.9	Confident	98 Å²	98	69.6 Å²	69.6	51%	0.513	38%	0.382	S	S	.	.	H	α-helix	trans	-67.3	-47.8	177.7	-175.7	72.6	0	0	0	110.7	V161 L162 L163 G167 W168 V169	V161-L165 VanDerWaalsContact O-CB 3.26Å; V161-L165 WeakPolarHBondContact O-CB 3.45Å; V161-L165 PolarHBondContact O-N 3.46Å; L162-L165 PolarHBondContact O-N 3.49Å; L163-L165 VanDerWaalsContact C-N 3.33Å; L163-L165 PolarHBondContact O-N 2.91Å; L165-G167 PolarHBondContact O-N 3.17Å; L165-W168 PolarHBondContact O-N 3.34Å; L165-V169 WeakPolarHBondContact O-CB 3.48Å; L165-V169 VanDerWaalsContact O-CG2 3.27Å; L165-V169 WeakPolarHBondContact O-CG2 3.49Å; L165-V169 PolarHBondContact O-N 3.35Å
166	C	88.4	Confident	87.4	Confident	27 Å²	27	69 Å²	69	18%	0.182	38%	0.379	C	S	.	.	H	α-helix	trans	-60	-45.3	175.5	-72.6	0	0	0	0	111.5	V127 L162 L163 V169 L170	V127-C166 HydrophobicContact CG1-CB 4.11Å; L162-C166 WeakPolarHBondContact O-CB 3.41Å; L162-C166 PolarHBondContact O-N 3.05Å; L162-C166 PolarHBondContact O-SG 2.85Å; L162-C166 VanDerWaalsContact O-SG 3.37Å; L163-C166 PolarHBondContact O-N 2.99Å; C166-V169 PolarHBondContact O-N 3.28Å; C166-L170 WeakPolarHBondContact O-CB 3.34Å; C166-L170 VanDerWaalsContact O-CG 3.26Å; C166-L170 WeakPolarHBondContact O-CG 3.14Å; C166-L170 PolarHBondContact O-N 3.35Å
167	G	88.3	Confident	87.8	Confident	38 Å²	38	65.7 Å²	65.7	39%	0.392	36%	0.362	S	S	.	.	H	α-helix	trans	-62.8	-42.5	176.5	0	0	0	0	0	112.9	L163 T164 L165 L170 C171	L163-G167 PolarHBondContact O-N 3.36Å; T164-G167 PolarHBondContact O-N 3.49Å; L165-G167 PolarHBondContact O-N 3.17Å; G167-L170 PolarHBondContact O-N 2.99Å; G167-C171 WeakPolarHBondContact O-CB 3.49Å; G167-C171 PolarHBondContact O-N 3.02Å
168	W	92.8	Very high	88.1	Confident	167 Å²	167	68 Å²	68	63%	0.633	36%	0.364	S	S	*	.	H	α-helix	trans	-61.3	-49.6	175.5	175.4	-93.7	0	0	0	111.7	T164 L165 L170 C171 W172	T164-W168 WeakPolarHBondContact O-CB 3.49Å; T164-W168 PolarHBondContact O-N 3.37Å; L165-W168 PolarHBondContact O-N 3.34Å; W168-L170 VanDerWaalsContact C-N 3.32Å; W168-L170 PolarHBondContact O-N 3.11Å; W168-C171 PolarHBondContact O-N 3.28Å; W168-W172 AromaticContact CE2-CE3 3.96Å; W168-W172 AromaticContact CZ2-CE3 3.81Å; W168-W172 HydrophobicContact CZ2-CE3 3.81Å; W168-W172 HydrophobicContact CZ2-CZ3 4.02Å; W168-W172 AromaticContact NE1-CE3 3.77Å; W168-W172 VanDerWaalsContact O-CB 3.26Å; W168-W172 WeakPolarHBondContact O-CB 3.35Å; W168-W172 PolarHBondContact O-N 2.89Å
169	V	92	Very high	88.4	Confident	46 Å²	46	75 Å²	75	28%	0.279	38%	0.379	S	S	.	.	H	α-helix	trans	-63	-39.6	178.7	174.4	0	0	0	0	111	V127 L165 C166 T173	V127-V169 HydrophobicContact CG2-CB 4.41Å; V127-V169 HydrophobicContact CG2-CG1 3.79Å; L165-V169 WeakPolarHBondContact O-CB 3.48Å; L165-V169 VanDerWaalsContact O-CG2 3.27Å; L165-V169 WeakPolarHBondContact O-CG2 3.49Å; L165-V169 PolarHBondContact O-N 3.35Å; C166-V169 PolarHBondContact O-N 3.28Å; V169-T173 HydrophobicContact CG1-CG2 4.24Å; V169-T173 WeakPolarHBondContact O-CB 3.3Å; V169-T173 VanDerWaalsContact O-CG2 3.24Å; V169-T173 WeakPolarHBondContact O-CG2 3.37Å; V169-T173 PolarHBondContact O-N 3.36Å; V169-T173 PolarHBondContact O-OG1 3.43Å
170	L	89.2	Confident	88.7	Confident	37 Å²	37	77.2 Å²	77.2	19%	0.194	40%	0.399	C	S	.	.	H	α-helix	trans	-62.1	-47.6	174	-75.9	171.3	0	0	0	112.1	F124 V127 M128 C166 G167 W168 T173 L174	F124-L170 HydrophobicContact CD2-CD2 3.81Å; F124-L170 HydrophobicContact CE2-CD2 3.98Å; V127-L170 HydrophobicContact CB-CD2 3.69Å; V127-L170 HydrophobicContact CB-CG 4.06Å; V127-L170 HydrophobicContact CG1-CD1 3.79Å; V127-L170 HydrophobicContact CG1-CD2 3.64Å; V127-L170 HydrophobicContact CG1-CG 3.48Å; V127-L170 VanDerWaalsContact CG1-CG 3.48Å; M128-L170 HydrophobicContact CE-CD1 3.35Å; M128-L170 HydrophobicContact CE-CD2 3.39Å; M128-L170 HydrophobicContact CE-CG 4Å; M128-L170 HydrophobicContact CG-CD2 4.38Å; C166-L170 WeakPolarHBondContact O-CB 3.34Å; C166-L170 VanDerWaalsContact O-CG 3.26Å; C166-L170 WeakPolarHBondContact O-CG 3.14Å; C166-L170 PolarHBondContact O-N 3.35Å; G167-L170 PolarHBondContact O-N 2.99Å; W168-L170 VanDerWaalsContact C-N 3.32Å; W168-L170 PolarHBondContact O-N 3.11Å; L170-T173 WeakPolarHBondContact CA-OG1 3.15Å; L170-T173 PolarHBondContact O-N 3.04Å; L170-T173 PolarHBondContact O-OG1 3.35Å; L170-L174 WeakPolarHBondContact O-CB 3.38Å; L170-L174 PolarHBondContact O-N 2.83Å
171	C	91.4	Very high	88.9	Confident	76 Å²	76	74 Å²	74	51%	0.514	38%	0.381	S	S	.	.	H	α-helix	trans	-63.2	-46.4	178.6	-170.6	0	0	0	0	111.1	G167 W168 T173 L174 V175	G167-C171 WeakPolarHBondContact O-CB 3.49Å; G167-C171 PolarHBondContact O-N 3.02Å; W168-C171 PolarHBondContact O-N 3.28Å; C171-T173 PolarHBondContact O-N 3.19Å; C171-L174 PolarHBondContact O-N 3.38Å; C171-V175 VanDerWaalsContact O-CG2 3.3Å; C171-V175 WeakPolarHBondContact O-CG2 3.37Å; C171-V175 PolarHBondContact O-N 3.09Å
172	W	93.3	Very high	88.8	Confident	140 Å²	140	72.7 Å²	72.7	53%	0.53	38%	0.376	S	S	.	.	H	α-helix	trans	-57.3	-50.9	177.3	179.2	-69.4	0	0	0	112	W168 V175 N176	W168-W172 AromaticContact CE2-CE3 3.96Å; W168-W172 AromaticContact CZ2-CE3 3.81Å; W168-W172 HydrophobicContact CZ2-CE3 3.81Å; W168-W172 HydrophobicContact CZ2-CZ3 4.02Å; W168-W172 AromaticContact NE1-CE3 3.77Å; W168-W172 VanDerWaalsContact O-CB 3.26Å; W168-W172 WeakPolarHBondContact O-CB 3.35Å; W168-W172 PolarHBondContact O-N 2.89Å; W172-V175 PolarHBondContact O-N 2.96Å; W172-N176 VanDerWaalsContact CD1-ND2 3.34Å; W172-N176 PolarHBondContact NE1-ND2 2.9Å; W172-N176 PolarHBondContact O-N 2.86Å; W172-N176 VanDerWaalsContact O-N 3.14Å; W172-N176 PolarHBondContact O-ND2 3.43Å
173	T	91.5	Very high	88.6	Confident	4 Å²	4	74.9 Å²	74.9	3%	0.025	39%	0.391	C	S	.	.	H	α-helix	trans	-63.8	-43.4	179.3	50.5	0	0	0	0	110.8	A123 V169 L170 C171 V175 N176 L177	A123-T173 HydrophobicContact CB-CG2 3.7Å; V169-T173 HydrophobicContact CG1-CG2 4.24Å; V169-T173 WeakPolarHBondContact O-CB 3.3Å; V169-T173 VanDerWaalsContact O-CG2 3.24Å; V169-T173 WeakPolarHBondContact O-CG2 3.37Å; V169-T173 PolarHBondContact O-N 3.36Å; V169-T173 PolarHBondContact O-OG1 3.43Å; L170-T173 WeakPolarHBondContact CA-OG1 3.15Å; L170-T173 PolarHBondContact O-N 3.04Å; L170-T173 PolarHBondContact O-OG1 3.35Å; C171-T173 PolarHBondContact O-N 3.19Å; T173-V175 PolarHBondContact O-N 3.38Å; T173-N176 PolarHBondContact O-N 2.93Å; T173-L177 WeakPolarHBondContact O-CD1 3.4Å; T173-L177 PolarHBondContact O-N 3.15Å
174	L	89.1	Confident	88.4	Confident	63 Å²	63	76 Å²	76	33%	0.33	40%	0.397	S	S	.	.	H	α-helix	trans	-59.9	-48.7	178.2	-171.9	66.3	0	0	0	111.9	L170 C171 N176 L177 F178 L189	L170-L174 WeakPolarHBondContact O-CB 3.38Å; L170-L174 PolarHBondContact O-N 2.83Å; C171-L174 PolarHBondContact O-N 3.38Å; L174-N176 VanDerWaalsContact C-N 3.28Å; L174-N176 PolarHBondContact O-N 3.39Å; L174-L177 PolarHBondContact O-N 3.07Å; L174-L177 VanDerWaalsContact O-N 3.16Å; L174-F178 HydrophobicContact CD1-CD2 4.08Å; L174-F178 HydrophobicContact CD1-CE2 3.62Å; L174-F178 HydrophobicContact CD2-CE2 4.09Å; L174-F178 HydrophobicContact CG-CD2 3.81Å; L174-F178 HydrophobicContact CG-CE2 3.57Å; L174-F178 WeakPolarHBondContact O-CD2 3.39Å; L174-F178 PolarHBondContact O-N 3.35Å; L174-L189 HydrophobicContact CD1-CD2 4.05Å
175	V	90.7	Very high	88.1	Confident	64 Å²	64	74.6 Å²	74.6	39%	0.388	39%	0.387	S	S	.	.	H	α-helix	trans	-57.9	-41.5	176.9	170.4	0	0	0	0	111.4	C171 W172 T173 F178 R179	C171-V175 VanDerWaalsContact O-CG2 3.3Å; C171-V175 WeakPolarHBondContact O-CG2 3.37Å; C171-V175 PolarHBondContact O-N 3.09Å; W172-V175 PolarHBondContact O-N 2.96Å; T173-V175 PolarHBondContact O-N 3.38Å; V175-F178 PolarHBondContact O-N 2.92Å; V175-R179 WeakPolarHBondContact O-CG 3.11Å; V175-R179 PolarHBondContact O-N 3.36Å; V175-R179 VanDerWaalsContact O-N 3.09Å
176	N	88.5	Confident	87.9	Confident	29 Å²	29	70.6 Å²	70.6	16%	0.155	37%	0.366	C	S	.	.	H	α-helix	trans	-71.5	-34.3	178.4	-69.5	-19	0	0	0	112.7	H120 W172 T173 L174 R179 S180	H120-N176 HydrophobicContact CB-CB 4.41Å; H120-N176 PolarHBondContact CE1-ND2 2.96Å; W172-N176 VanDerWaalsContact CD1-ND2 3.34Å; W172-N176 PolarHBondContact NE1-ND2 2.9Å; W172-N176 PolarHBondContact O-N 2.86Å; W172-N176 VanDerWaalsContact O-N 3.14Å; W172-N176 PolarHBondContact O-ND2 3.43Å; T173-N176 PolarHBondContact O-N 2.93Å; L174-N176 VanDerWaalsContact C-N 3.28Å; L174-N176 PolarHBondContact O-N 3.39Å; N176-R179 PolarHBondContact O-N 3.36Å; N176-S180 WeakPolarHBondContact O-CB 3.41Å; N176-S180 PolarHBondContact O-N 2.85Å; N176-S180 PolarHBondContact O-OG 3.22Å
177	L	88.9	Confident	87.7	Confident	0 Å²	0	74.8 Å²	74.8	0%	0	39%	0.386	C	S	.	.	H	α-helix	trans	-64.5	-41.3	171.4	-92.4	75.8	0	0	0	111	H120 L121 T173 L174 R179 S180 H181 L186 L189 F306	H120-L177 HydrophobicContact CB-CD1 3.3Å; L121-L177 HydrophobicContact CD1-CD2 4.01Å; T173-L177 WeakPolarHBondContact O-CD1 3.4Å; T173-L177 PolarHBondContact O-N 3.15Å; L174-L177 PolarHBondContact O-N 3.07Å; L174-L177 VanDerWaalsContact O-N 3.16Å; L177-R179 VanDerWaalsContact C-N 3.25Å; L177-R179 PolarHBondContact O-N 3.36Å; L177-S180 PolarHBondContact O-N 3.22Å; L177-S180 VanDerWaalsContact O-N 3.16Å; L177-H181 PolarHBondContact O-N 2.97Å; L177-L186 HydrophobicContact CB-CD2 3.78Å; L177-L189 HydrophobicContact CD2-CD1 4.11Å; L177-L189 HydrophobicContact CD2-CD2 3.75Å; L177-F306 HydrophobicContact CD2-CE1 4.33Å; L177-F306 HydrophobicContact CD2-CZ 4.46Å
178	F	87.6	Confident	87.6	Confident	112 Å²	112	76.9 Å²	76.9	49%	0.491	38%	0.384	S	S	.	.	H	α-helix	trans	-61.1	-33.3	175	-88.1	-74.1	0	0	0	113	L174 V175 L186	L174-F178 HydrophobicContact CD1-CD2 4.08Å; L174-F178 HydrophobicContact CD1-CE2 3.62Å; L174-F178 HydrophobicContact CD2-CE2 4.09Å; L174-F178 HydrophobicContact CG-CD2 3.81Å; L174-F178 HydrophobicContact CG-CE2 3.57Å; L174-F178 WeakPolarHBondContact O-CD2 3.39Å; L174-F178 PolarHBondContact O-N 3.35Å; V175-F178 PolarHBondContact O-N 2.92Å; F178-L186 HydrophobicContact CB-CD1 4.46Å; F178-L186 HydrophobicContact CD1-CD1 3.51Å; F178-L186 HydrophobicContact CD1-CD2 4.26Å; F178-L186 HydrophobicContact CD1-CG 4.4Å; F178-L186 HydrophobicContact CD2-CD2 4.17Å; F178-L186 HydrophobicContact CE1-CB 4.31Å; F178-L186 HydrophobicContact CE1-CD1 3.8Å; F178-L186 HydrophobicContact CE1-CD2 4.29Å; F178-L186 HydrophobicContact CE1-CG 4.36Å; F178-L186 HydrophobicContact CE2-CD2 4.21Å; F178-L186 HydrophobicContact CG-CD1 4.02Å; F178-L186 HydrophobicContact CG-CD2 4.16Å; F178-L186 HydrophobicContact CZ-CD2 4.25Å
179	R	86.8	Confident	87.3	Confident	202 Å²	202	69.3 Å²	69.3	76%	0.762	36%	0.356	S	S	*	.	H	α-helix	trans	-76.4	-29.9	175.9	-72.8	177.2	174.3	-176.8	-2	113.2	V175 N176 L177	V175-R179 WeakPolarHBondContact O-CG 3.11Å; V175-R179 PolarHBondContact O-N 3.36Å; V175-R179 VanDerWaalsContact O-N 3.09Å; N176-R179 PolarHBondContact O-N 3.36Å; L177-R179 VanDerWaalsContact C-N 3.25Å; L177-R179 PolarHBondContact O-N 3.36Å
180	S	84.5	Confident	86.7	Confident	78 Å²	78	68.8 Å²	68.8	55%	0.545	36%	0.361	S	S	.	.	H	α-helix	trans	-99.7	-26.9	-168.9	-51.9	0	0	0	0	113.8	N176 L177	N176-S180 WeakPolarHBondContact O-CB 3.41Å; N176-S180 PolarHBondContact O-N 2.85Å; N176-S180 PolarHBondContact O-OG 3.22Å; L177-S180 PolarHBondContact O-N 3.22Å; L177-S180 VanDerWaalsContact O-N 3.16Å
181	H	86.1	Confident	86.5	Confident	50 Å²	50	73.4 Å²	73.4	23%	0.231	38%	0.376	C	S	.	.	S	Bend	trans	-123.9	157.9	-172.9	-67.5	-75.5	0	0	0	113	D118 L177 N185 F306	D118-H181 IonicContact OD2-CD2 3.61Å; D118-H181 IonicContact OD2-CE1 3.76Å; D118-H181 IonicContact OD2-NE2 2.73Å; D118-H181 PolarHBondContact OD2-NE2 3.29Å; L177-H181 PolarHBondContact O-N 2.97Å; H181-N185 HydrophobicContact CB-CB 4.34Å; H181-F306 HydrophobicContact CB-CE1 4.18Å; H181-F306 AromaticContact CD2-CD1 3.91Å; H181-F306 AromaticContact CD2-CE1 3.79Å; H181-F306 AromaticContact CE1-CD1 3.72Å; H181-F306 AromaticContact CG-CD1 3.94Å; H181-F306 AromaticContact CG-CE1 3.76Å; H181-F306 AromaticContact ND1-CD1 3.83Å; H181-F306 AromaticContact NE2-CD1 3.76Å
182	S	85.8	Confident	85.9	Confident	64 Å²	64	70.3 Å²	70.3	45%	0.448	36%	0.355	S	S	.	.			trans	-67.6	152.2	175.8	69.3	0	0	0	0	111.9	L184 N185 L186	S182-L184 PolarHBondContact O-N 2.96Å; S182-L184 VanDerWaalsContact O-N 3.17Å; S182-N185 PolarHBondContact O-N 2.67Å; S182-L186 WeakPolarHBondContact O-CD1 3.09Å; S182-L186 PolarHBondContact O-N 2.95Å
183	V	82.6	Confident	85	Confident	103 Å²	103	66.4 Å²	66.4	62%	0.624	34%	0.342	S	S	*	.	H	α-helix	trans	-56.7	-32.8	178.6	-178.3	0	0	0	0	112.1	L186 L187	V183-L186 WeakPolarHBondContact O-CB 3.34Å; V183-L186 PolarHBondContact O-N 3.48Å; V183-L187 PolarHBondContact O-N 2.93Å
184	L	81.6	Confident	84	Confident	124 Å²	124	68.7 Å²	68.7	65%	0.649	37%	0.366	S	S	*	.	H	α-helix	trans	-62.9	-42.6	176.2	-69	174.7	0	0	0	112.3	S182 L186 L187	S182-L184 PolarHBondContact O-N 2.96Å; S182-L184 VanDerWaalsContact O-N 3.17Å; L184-L186 PolarHBondContact O-N 3.48Å; L184-L187 HydrophobicContact CD2-CD1 4.28Å; L184-L187 WeakPolarHBondContact O-CB 3.26Å; L184-L187 PolarHBondContact O-N 3.32Å
185	N	81.5	Confident	83.2	Confident	44 Å²	44	68.4 Å²	68.4	24%	0.235	37%	0.367	C	S	.	.	H	α-helix	trans	-65.5	-34.6	177.3	-70.4	-2.9	0	0	0	111.2	H181 S182 L187 F188 F306	H181-N185 HydrophobicContact CB-CB 4.34Å; S182-N185 PolarHBondContact O-N 2.67Å; N185-L187 VanDerWaalsContact C-N 3.34Å; N185-F188 WeakPolarHBondContact O-CB 3.3Å; N185-F188 PolarHBondContact O-N 3.41Å; N185-F306 HydrophobicContact CB-CE1 4Å; N185-F306 HydrophobicContact CB-CZ 3.99Å; N185-F306 WeakPolarHBondContact O-CZ 3.38Å
186	L	84.3	Confident	82.1	Confident	14 Å²	14	66.5 Å²	66.5	7%	0.073	35%	0.353	C	S	.	.	H	α-helix	trans	-70.7	-27.7	177.6	-72.3	146.9	0	0	0	113.1	L177 F178 S182 V183 L184 F188 L189	L177-L186 HydrophobicContact CB-CD2 3.78Å; F178-L186 HydrophobicContact CB-CD1 4.46Å; F178-L186 HydrophobicContact CD1-CD1 3.51Å; F178-L186 HydrophobicContact CD1-CD2 4.26Å; F178-L186 HydrophobicContact CD1-CG 4.4Å; F178-L186 HydrophobicContact CD2-CD2 4.17Å; F178-L186 HydrophobicContact CE1-CB 4.31Å; F178-L186 HydrophobicContact CE1-CD1 3.8Å; F178-L186 HydrophobicContact CE1-CD2 4.29Å; F178-L186 HydrophobicContact CE1-CG 4.36Å; F178-L186 HydrophobicContact CE2-CD2 4.21Å; F178-L186 HydrophobicContact CG-CD1 4.02Å; F178-L186 HydrophobicContact CG-CD2 4.16Å; F178-L186 HydrophobicContact CZ-CD2 4.25Å; S182-L186 WeakPolarHBondContact O-CD1 3.09Å; S182-L186 PolarHBondContact O-N 2.95Å; V183-L186 WeakPolarHBondContact O-CB 3.34Å; V183-L186 PolarHBondContact O-N 3.48Å; L184-L186 PolarHBondContact O-N 3.48Å; L186-F188 PolarHBondContact O-N 3.33Å; L186-L189 WeakPolarHBondContact O-CB 3.43Å; L186-L189 PolarHBondContact O-N 2.84Å; L186-L189 VanDerWaalsContact O-N 3.15Å
187	L	84.8	Confident	81	Confident	116 Å²	116	65.7 Å²	65.7	61%	0.607	35%	0.349	S	S	*	.	H	α-helix	trans	-62.8	-29.9	172.9	-72.7	171.7	0	0	0	112.1	V183 L184 N185 L189 G190 Y191	V183-L187 PolarHBondContact O-N 2.93Å; L184-L187 HydrophobicContact CD2-CD1 4.28Å; L184-L187 WeakPolarHBondContact O-CB 3.26Å; L184-L187 PolarHBondContact O-N 3.32Å; N185-L187 VanDerWaalsContact C-N 3.34Å; L187-L189 VanDerWaalsContact C-N 3.29Å; L187-L189 PolarHBondContact O-N 2.8Å; L187-G190 PolarHBondContact O-N 2.76Å; L187-Y191 PolarHBondContact O-N 3.25Å
188	F	86.4	Confident	79.9	Confident	81 Å²	81	68.4 Å²	68.4	36%	0.355	37%	0.367	S	S	.	.	H	α-helix	trans	-64.7	-31.8	175.3	-66.1	-62.7	0	0	0	112.4	N185 L186 G190 Y191 Y297 L302 C305	N185-F188 WeakPolarHBondContact O-CB 3.3Å; N185-F188 PolarHBondContact O-N 3.41Å; L186-F188 PolarHBondContact O-N 3.33Å; F188-G190 PolarHBondContact O-N 3.49Å; F188-Y191 PolarHBondContact O-N 3.15Å; F188-Y297 WeakPolarHBondContact O-CE1 3.17Å; F188-Y297 PolarHBondContact O-OH 2.87Å; F188-L302 HydrophobicContact CB-CD1 4.18Å; F188-C305 HydrophobicContact CD2-CB 4.25Å
189	L	85.8	Confident	78.8	Confident	8 Å²	8	68.6 Å²	68.6	4%	0.042	37%	0.372	C	S	.	.	H	α-helix	trans	-57.4	-40.5	174.4	-90.7	68.1	0	0	0	111.5	F124 L174 L177 L186 L187 Y298 L302 F306	F124-L189 HydrophobicContact CD1-CD2 3.69Å; F124-L189 HydrophobicContact CD1-CG 4.01Å; F124-L189 HydrophobicContact CD2-CD2 4.27Å; F124-L189 HydrophobicContact CE1-CB 4.14Å; F124-L189 HydrophobicContact CE1-CD2 3.3Å; F124-L189 HydrophobicContact CE1-CG 3.42Å; F124-L189 VanDerWaalsContact CE1-CG 3.42Å; F124-L189 HydrophobicContact CE2-CD2 3.95Å; F124-L189 HydrophobicContact CG-CD2 4.16Å; F124-L189 HydrophobicContact CZ-CB 4.29Å; F124-L189 HydrophobicContact CZ-CD2 3.46Å; F124-L189 VanDerWaalsContact CZ-CD2 3.46Å; F124-L189 HydrophobicContact CZ-CG 3.92Å; L174-L189 HydrophobicContact CD1-CD2 4.05Å; L177-L189 HydrophobicContact CD2-CD1 4.11Å; L177-L189 HydrophobicContact CD2-CD2 3.75Å; L186-L189 WeakPolarHBondContact O-CB 3.43Å; L186-L189 PolarHBondContact O-N 2.84Å; L186-L189 VanDerWaalsContact O-N 3.15Å; L187-L189 VanDerWaalsContact C-N 3.29Å; L187-L189 PolarHBondContact O-N 2.8Å; L189-Y298 PolarHBondContact O-OH 2.96Å; L189-L302 HydrophobicContact CD1-CD1 4.17Å; L189-F306 HydrophobicContact CD1-CE1 4.47Å; L189-F306 HydrophobicContact CD1-CE2 3.57Å; L189-F306 HydrophobicContact CD1-CZ 3.34Å
190	G	81.2	Confident	77.6	Confident	36 Å²	36	60.3 Å²	60.3	37%	0.371	35%	0.345	S	S	.	.	H	α-helix	trans	-85.5	-7.4	-177	0	0	0	0	0	115.2	L187 F188 F193 G194	L187-G190 PolarHBondContact O-N 2.76Å; F188-G190 PolarHBondContact O-N 3.49Å; G190-F193 WeakPolarHBondContact O-CB 3.4Å; G190-F193 PolarHBondContact O-N 3.37Å; G190-G194 PolarHBondContact O-N 3.44Å
191	Y	83.9	Confident	76.3	Confident	133 Å²	133	57.4 Å²	57.4	52%	0.522	33%	0.325	S	S	.	.	H	α-helix	trans	-58.1	-45.4	-167.4	-178.7	-95.3	0	0	0	114.3	L187 F188 F193 G194 V195 Y297	L187-Y191 PolarHBondContact O-N 3.25Å; F188-Y191 PolarHBondContact O-N 3.15Å; Y191-F193 PolarHBondContact O-N 3.35Å; Y191-G194 PolarHBondContact O-N 3.19Å; Y191-G194 VanDerWaalsContact O-N 3.14Å; Y191-V195 HydrophobicContact CD1-CG2 4.26Å; Y191-V195 HydrophobicContact CD2-CG2 4.24Å; Y191-V195 HydrophobicContact CE1-CG2 3.77Å; Y191-V195 HydrophobicContact CE2-CG2 3.76Å; Y191-V195 HydrophobicContact CG-CG2 4.48Å; Y191-V195 PolarHBondContact O-N 2.8Å; Y191-Y297 AromaticContact CD1-CE2 3.94Å; Y191-Y297 HydrophobicContact CD1-CE2 3.94Å
192	P	79.8	Confident	74.9	Confident	11 Å²	11	62.2 Å²	62.2	7%	0.071	35%	0.345	C	S	.	.	H	α-helix	trans	-60.6	-32.4	177.6	-28.2	40.3	0	0	0	113.3	Y196 F294 Y297 Y298	P192-Y196 WeakPolarHBondContact O-CB 3.06Å; P192-Y196 PolarHBondContact O-N 2.92Å; P192-Y196 VanDerWaalsContact O-N 3.13Å; P192-F294 HydrophobicContact CB-CD2 3.71Å; P192-F294 HydrophobicContact CB-CE2 4.04Å; P192-F294 HydrophobicContact CG-CD2 4.35Å; P192-F294 HydrophobicContact CG-CE2 4.49Å; P192-Y297 HydrophobicContact CG-CD1 3.38Å; P192-Y297 HydrophobicContact CG-CD2 4.17Å; P192-Y297 HydrophobicContact CG-CE1 3.63Å; P192-Y297 HydrophobicContact CG-CE2 4.36Å; P192-Y297 HydrophobicContact CG-CG 3.69Å; P192-Y298 HydrophobicContact CG-CE2 3.9Å
193	F	73.4	Confident	73.5	Confident	58 Å²	58	63 Å²	63	25%	0.254	34%	0.342	S	S	.	.	H	α-helix	trans	-74.2	-40.2	176.1	-60	-77.4	0	0	0	111.7	G190 Y191 V195 Y196 V197 L248 F294 Y298	G190-F193 WeakPolarHBondContact O-CB 3.4Å; G190-F193 PolarHBondContact O-N 3.37Å; Y191-F193 PolarHBondContact O-N 3.35Å; F193-V195 VanDerWaalsContact C-N 3.33Å; F193-V195 PolarHBondContact O-N 3.38Å; F193-Y196 PolarHBondContact O-N 3.21Å; F193-V197 VanDerWaalsContact O-CG2 3.27Å; F193-V197 WeakPolarHBondContact O-CG2 3.36Å; F193-V197 PolarHBondContact O-N 3.47Å; F193-L248 HydrophobicContact CE1-CD2 4.43Å; F193-F294 HydrophobicContact CE1-CE2 4.33Å; F193-F294 AromaticContact CE2-CE2 3.87Å; F193-F294 HydrophobicContact CE2-CE2 3.87Å; F193-F294 HydrophobicContact CE2-CZ 4.36Å; F193-F294 AromaticContact CZ-CE2 3.7Å; F193-F294 HydrophobicContact CZ-CE2 3.7Å; F193-F294 HydrophobicContact CZ-CZ 4.15Å; F193-Y298 WeakPolarHBondContact CE2-OH 3.3Å
194	G	71.2	Confident	72.2	Confident	52 Å²	52	61.8 Å²	61.8	54%	0.536	33%	0.329	S	S	.	.	H	α-helix	trans	-65.2	-32.1	178.7	0	0	0	0	0	114	G190 Y191 P198	G190-G194 PolarHBondContact O-N 3.44Å; Y191-G194 PolarHBondContact O-N 3.19Å; Y191-G194 VanDerWaalsContact O-N 3.14Å; G194-P198 WeakPolarHBondContact O-CD 3.44Å; G194-P198 VanDerWaalsContact O-CG 3.29Å; G194-P198 WeakPolarHBondContact O-CG 3.34Å
195	V	71.6	Confident	70.5	Confident	57 Å²	57	59.9 Å²	59.9	35%	0.345	32%	0.319	S	S	.	.	H	α-helix	trans	-84.9	-35.4	176.3	178	0	0	0	0	111.9	Y191 F193 L199	Y191-V195 HydrophobicContact CD1-CG2 4.26Å; Y191-V195 HydrophobicContact CD2-CG2 4.24Å; Y191-V195 HydrophobicContact CE1-CG2 3.77Å; Y191-V195 HydrophobicContact CE2-CG2 3.76Å; Y191-V195 HydrophobicContact CG-CG2 4.48Å; Y191-V195 PolarHBondContact O-N 2.8Å; F193-V195 VanDerWaalsContact C-N 3.33Å; F193-V195 PolarHBondContact O-N 3.38Å; V195-L199 HydrophobicContact CG1-CD1 3.75Å; V195-L199 WeakPolarHBondContact O-CD1 3.49Å; V195-L199 VanDerWaalsContact O-CG 3.29Å; V195-L199 WeakPolarHBondContact O-CG 3.24Å
196	Y	67.3	Low	68.8	Low	24 Å²	24	61.4 Å²	61.4	9%	0.094	33%	0.334	C	S	.	.	H	α-helix	trans	-71	-45.4	-175.2	-175.1	-118.4	0	0	0	114	P192 F193 L199 C200 S247 Q251 F290	P192-Y196 WeakPolarHBondContact O-CB 3.06Å; P192-Y196 PolarHBondContact O-N 2.92Å; P192-Y196 VanDerWaalsContact O-N 3.13Å; F193-Y196 PolarHBondContact O-N 3.21Å; Y196-L199 PolarHBondContact O-N 2.82Å; Y196-C200 VanDerWaalsContact CD2-SG 3.57Å; Y196-C200 WeakPolarHBondContact CE2-SG 3.41Å; Y196-C200 PolarHBondContact O-N 3.01Å; Y196-C200 PolarHBondContact O-SG 3.42Å; Y196-C200 VanDerWaalsContact O-SG 3.35Å; Y196-S247 VanDerWaalsContact CD1-OG 3.32Å; Y196-S247 WeakPolarHBondContact CD1-OG 3.37Å; Y196-S247 WeakPolarHBondContact CE1-OG 3.43Å; Y196-Q251 HydrophobicContact CE1-CG 4.26Å; Y196-F290 VanDerWaalsContact CB-CE2 3.45Å; Y196-F290 HydrophobicContact CD1-CE2 4.24Å; Y196-F290 HydrophobicContact CD1-CZ 4.18Å; Y196-F290 HydrophobicContact CD2-CB 4.31Å; Y196-F290 HydrophobicContact CD2-CD1 4.23Å; Y196-F290 AromaticContact CD2-CD2 3.01Å; Y196-F290 HydrophobicContact CD2-CD2 3.01Å; Y196-F290 HydrophobicContact CD2-CE1 4.43Å; Y196-F290 AromaticContact CD2-CE2 3.24Å; Y196-F290 HydrophobicContact CD2-CE2 3.24Å; Y196-F290 AromaticContact CD2-CG 3.53Å; Y196-F290 HydrophobicContact CD2-CG 3.53Å; Y196-F290 AromaticContact CD2-CZ 3.94Å; Y196-F290 HydrophobicContact CD2-CZ 3.94Å; Y196-F290 HydrophobicContact CE2-CB 3.81Å; Y196-F290 AromaticContact CE2-CD1 3.95Å; Y196-F290 HydrophobicContact CE2-CD1 3.95Å; Y196-F290 AromaticContact CE2-CD2 3.39Å; Y196-F290 HydrophobicContact CE2-CD2 3.39Å; Y196-F290 HydrophobicContact CE2-CE1 4.48Å; Y196-F290 AromaticContact CE2-CE2 3.96Å; Y196-F290 HydrophobicContact CE2-CE2 3.96Å; Y196-F290 AromaticContact CE2-CG 3.34Å; Y196-F290 HydrophobicContact CE2-CG 3.34Å; Y196-F290 HydrophobicContact CE2-CZ 4.43Å; Y196-F290 AromaticContact CG-CD2 3.71Å; Y196-F290 HydrophobicContact CG-CD2 3.71Å; Y196-F290 HydrophobicContact CG-CE1 4.47Å; Y196-F290 AromaticContact CG-CE2 3.39Å; Y196-F290 HydrophobicContact CG-CE2 3.39Å; Y196-F290 HydrophobicContact CG-CG 4.32Å; Y196-F290 AromaticContact CG-CZ 3.78Å; Y196-F290 HydrophobicContact CG-CZ 3.78Å
197	V	65.8	Low	67.1	Low	13 Å²	13	65.9 Å²	65.9	8%	0.079	35%	0.35	C	S	.	.	H	α-helix	trans	-61.2	-47.2	-173.3	172.3	0	0	0	0	110.9	F193 L199 C200 C201 F240 L244	F193-V197 VanDerWaalsContact O-CG2 3.27Å; F193-V197 WeakPolarHBondContact O-CG2 3.36Å; F193-V197 PolarHBondContact O-N 3.47Å; V197-L199 PolarHBondContact O-N 2.75Å; V197-C200 PolarHBondContact O-N 3.4Å; V197-C201 WeakPolarHBondContact O-CB 3.08Å; V197-C201 PolarHBondContact O-N 3.39Å; V197-C201 PolarHBondContact O-SG 2.92Å; V197-F240 HydrophobicContact CG1-CE2 3.74Å; V197-F240 HydrophobicContact CG1-CZ 3.83Å; V197-L244 HydrophobicContact CB-CD2 4.36Å; V197-L244 HydrophobicContact CG1-CD2 3.95Å; V197-L244 HydrophobicContact CG1-CG 3.94Å; V197-L244 HydrophobicContact CG2-CD2 3.5Å; V197-L244 HydrophobicContact CG2-CG 4.39Å
198	P	66.1	Low	65.1	Low	56 Å²	56	62.6 Å²	62.6	36%	0.364	34%	0.339	S	S	.	.	H	α-helix	trans	-61.5	-44.6	173.6	-23.2	34.5	0	0	0	113.1	G194 C200 C201 F202	G194-P198 WeakPolarHBondContact O-CD 3.44Å; G194-P198 VanDerWaalsContact O-CG 3.29Å; G194-P198 WeakPolarHBondContact O-CG 3.34Å; P198-C200 VanDerWaalsContact C-N 3.31Å; P198-C200 PolarHBondContact O-N 2.97Å; P198-C201 PolarHBondContact O-N 3.14Å; P198-F202 HydrophobicContact CB-CD2 4.31Å; P198-F202 HydrophobicContact CB-CE2 4.32Å; P198-F202 WeakPolarHBondContact O-CB 3.2Å; P198-F202 WeakPolarHBondContact O-CD2 3.3Å; P198-F202 PolarHBondContact O-N 3.15Å
199	L	64.8	Low	62.9	Low	117 Å²	117	65.6 Å²	65.6	61%	0.613	35%	0.354	S	S	*	.	H	α-helix	trans	-63.2	-36.2	-178.1	-73.1	173.5	0	0	0	112.8	V195 Y196 V197 H203	V195-L199 HydrophobicContact CG1-CD1 3.75Å; V195-L199 WeakPolarHBondContact O-CD1 3.49Å; V195-L199 VanDerWaalsContact O-CG 3.29Å; V195-L199 WeakPolarHBondContact O-CG 3.24Å; Y196-L199 PolarHBondContact O-N 2.82Å; V197-L199 PolarHBondContact O-N 2.75Å; L199-H203 WeakPolarHBondContact O-CB 3.35Å; L199-H203 PolarHBondContact O-N 2.92Å
200	C	60.8	Low	60.9	Low	28 Å²	28	70.5 Å²	70.5	19%	0.189	38%	0.38	C	S	.	.	H	α-helix	trans	-72.7	-45.8	175	-66.1	0	0	0	0	111.5	Y196 V197 P198 H203 Q204	Y196-C200 VanDerWaalsContact CD2-SG 3.57Å; Y196-C200 WeakPolarHBondContact CE2-SG 3.41Å; Y196-C200 PolarHBondContact O-N 3.01Å; Y196-C200 PolarHBondContact O-SG 3.42Å; Y196-C200 VanDerWaalsContact O-SG 3.35Å; V197-C200 PolarHBondContact O-N 3.4Å; P198-C200 VanDerWaalsContact C-N 3.31Å; P198-C200 PolarHBondContact O-N 2.97Å; C200-H203 PolarHBondContact O-N 3.36Å; C200-Q204 WeakPolarHBondContact O-CB 3.36Å; C200-Q204 PolarHBondContact O-N 3.21Å
201	C	58.1	Low	59.2	Low	17 Å²	17	74.4 Å²	74.4	12%	0.115	39%	0.391	C	S	.	.	H	α-helix	trans	-58.2	-50.6	177.3	-67.2	0	0	0	0	111.7	V197 P198 H203 Q204 D205	V197-C201 WeakPolarHBondContact O-CB 3.08Å; V197-C201 PolarHBondContact O-N 3.39Å; V197-C201 PolarHBondContact O-SG 2.92Å; P198-C201 PolarHBondContact O-N 3.14Å; C201-H203 VanDerWaalsContact C-N 3.26Å; C201-H203 PolarHBondContact O-N 3.32Å; C201-Q204 PolarHBondContact O-N 3.34Å; C201-Q204 VanDerWaalsContact O-N 3.15Å; C201-D205 WeakPolarHBondContact O-CB 3.41Å; C201-D205 PolarHBondContact O-N 3.34Å
202	F	56.8	Low	57.4	Low	151 Å²	151	72.9 Å²	72.9	66%	0.662	39%	0.392	S	S	*	.	H	α-helix	trans	-59.8	-35.6	179.1	-82.4	-65.7	0	0	0	113.1	P198 S206	P198-F202 HydrophobicContact CB-CD2 4.31Å; P198-F202 HydrophobicContact CB-CE2 4.32Å; P198-F202 WeakPolarHBondContact O-CB 3.2Å; P198-F202 WeakPolarHBondContact O-CD2 3.3Å; P198-F202 PolarHBondContact O-N 3.15Å; F202-S206 PolarHBondContact O-N 2.83Å; F202-S206 PolarHBondContact O-OG 3.34Å
203	H	54.8	Low	55.5	Low	80 Å²	80	76.3 Å²	76.3	37%	0.37	41%	0.413	S	S	.	.	H	α-helix	trans	-78.3	-32.9	178.5	-171.7	-79	0	0	0	112.8	L199 C200 C201 K286	L199-H203 WeakPolarHBondContact O-CB 3.35Å; L199-H203 PolarHBondContact O-N 2.92Å; C200-H203 PolarHBondContact O-N 3.36Å; C201-H203 VanDerWaalsContact C-N 3.26Å; C201-H203 PolarHBondContact O-N 3.32Å; H203-K286 PolarHBondContact CD2-NZ 3.33Å; H203-K286 PolarHBondContact CE1-NZ 3.22Å; H203-K286 PolarHBondContact ND1-NZ 3.3Å; H203-K286 PolarHBondContact NE2-NZ 2.93Å
204	Q	55.3	Low	53.8	Low	77 Å²	77	78.7 Å²	78.7	36%	0.36	43%	0.428	S	S	.	.	H	α-helix	trans	-68.9	-44.6	175.6	-160.7	112.8	-10.4	0	0	110.9	C200 C201 S206 R207 A208	C200-Q204 WeakPolarHBondContact O-CB 3.36Å; C200-Q204 PolarHBondContact O-N 3.21Å; C201-Q204 PolarHBondContact O-N 3.34Å; C201-Q204 VanDerWaalsContact O-N 3.15Å; Q204-S206 PolarHBondContact O-N 3.26Å; Q204-R207 PolarHBondContact O-N 3.46Å; Q204-R207 VanDerWaalsContact O-N 3.12Å; Q204-A208 PolarHBondContact O-N 3.1Å
205	D	47.6	Very low	52	Low	84 Å²	84	84.1 Å²	84.1	45%	0.449	43%	0.433	S	S	.	.	H	α-helix	trans	-64.8	-39	-179.3	-71.6	-24.5	0	0	0	112.1	C201 R207 A208 H209	C201-D205 WeakPolarHBondContact O-CB 3.41Å; C201-D205 PolarHBondContact O-N 3.34Å; D205-R207 PolarHBondContact O-N 3.43Å; D205-A208 PolarHBondContact O-N 3.37Å; D205-H209 PolarHBondContact O-N 3.24Å; D205-H209 VanDerWaalsContact O-N 3.17Å
206	S	44.8	Very low	50.3	Low	77 Å²	77	86.1 Å²	86.1	54%	0.538	44%	0.442	S	S	.	.	H	α-helix	trans	-59.6	-29.8	174.7	-63.2	0	0	0	0	112.9	F202 Q204	F202-S206 PolarHBondContact O-N 2.83Å; F202-S206 PolarHBondContact O-OG 3.34Å; Q204-S206 PolarHBondContact O-N 3.26Å
207	R	49.6	Very low	48.8	Very low	108 Å²	108	93.7 Å²	93.7	41%	0.408	47%	0.472	S	S	.	.	H	α-helix	trans	-93.6	-33.1	-178.5	-68.5	-175.2	78	175.3	9.2	113.5	Q204 D205 H209 L210 L211 A279	Q204-R207 PolarHBondContact O-N 3.46Å; Q204-R207 VanDerWaalsContact O-N 3.12Å; D205-R207 PolarHBondContact O-N 3.43Å; R207-H209 PolarHBondContact O-N 2.77Å; R207-L210 PolarHBondContact O-N 3.12Å; R207-L211 PolarHBondContact O-N 3.38Å; R207-A279 VanDerWaalsContact NH2-CB 3.3Å
208	A	42.8	Very low	47.6	Very low	47 Å²	47	97.8 Å²	97.8	39%	0.388	50%	0.497	S	S	.	.	H	α-helix	trans	-58.9	-39.5	170.3	0	0	0	0	0	110.4	Q204 D205 L212	Q204-A208 PolarHBondContact O-N 3.1Å; D205-A208 PolarHBondContact O-N 3.37Å; A208-L212 VanDerWaalsContact O-CB 3.22Å; A208-L212 WeakPolarHBondContact O-CB 3.47Å; A208-L212 WeakPolarHBondContact O-CG 3.48Å; A208-L212 PolarHBondContact O-N 3.31Å
209	H	38.8	Very low	46.3	Very low	144 Å²	144	98.4 Å²	98.4	67%	0.667	50%	0.5	S	S	*	.	H	α-helix	trans	-64.1	-39.5	174.5	-113.9	-83	0	0	0	113.7	D205 R207 T213	D205-H209 PolarHBondContact O-N 3.24Å; D205-H209 VanDerWaalsContact O-N 3.17Å; R207-H209 PolarHBondContact O-N 2.77Å; H209-T213 PolarHBondContact O-N 3Å; H209-T213 VanDerWaalsContact O-N 3.12Å; H209-T213 PolarHBondContact O-OG1 2.88Å
210	L	43.6	Very low	44.7	Very low	110 Å²	110	99.9 Å²	99.9	58%	0.576	50%	0.503	S	S	*	.	H	α-helix	trans	-71.7	-42.4	178	-92.8	157.8	0	0	0	113	R207 T213 D214	R207-L210 PolarHBondContact O-N 3.12Å; L210-T213 VanDerWaalsContact CA-OG1 3.3Å; L210-T213 WeakPolarHBondContact CA-OG1 3.31Å; L210-T213 PolarHBondContact O-N 3.5Å; L210-T213 PolarHBondContact O-OG1 2.69Å; L210-D214 PolarHBondContact O-N 3.21Å
211	L	45.7	Very low	43.4	Very low	118 Å²	118	106.6 Å²	106.6	62%	0.618	53%	0.532	S	S	*	.	H	α-helix	trans	-72.4	-34	177.6	-68.9	179.1	0	0	0	112.2	R207 T213 Y215	R207-L211 PolarHBondContact O-N 3.38Å; L211-T213 VanDerWaalsContact C-N 3.33Å; L211-Y215 VanDerWaalsContact O-CB 3.23Å; L211-Y215 WeakPolarHBondContact O-CB 3.44Å; L211-Y215 PolarHBondContact O-N 3.4Å
212	L	47.7	Very low	42.1	Very low	102 Å²	102	114.2 Å²	114.2	53%	0.534	57%	0.565	S	S	.	*	H	α-helix	trans	-70	-29.6	172.5	-75.1	171.6	0	0	0	112.4	A208 N216	A208-L212 VanDerWaalsContact O-CB 3.22Å; A208-L212 WeakPolarHBondContact O-CB 3.47Å; A208-L212 WeakPolarHBondContact O-CG 3.48Å; A208-L212 PolarHBondContact O-N 3.31Å; L212-N216 WeakPolarHBondContact O-CB 3.31Å; L212-N216 VanDerWaalsContact O-CG 3.28Å; L212-N216 PolarHBondContact O-N 3.28Å
213	T	40	Very low	41	Very low	82 Å²	82	110.3 Å²	110.3	50%	0.503	56%	0.561	S	S	.	*	H	α-helix	trans	-73.8	-40.6	174.3	26.2	0	0	0	0	112.1	H209 L210 L211 Y217	H209-T213 PolarHBondContact O-N 3Å; H209-T213 VanDerWaalsContact O-N 3.12Å; H209-T213 PolarHBondContact O-OG1 2.88Å; L210-T213 VanDerWaalsContact CA-OG1 3.3Å; L210-T213 WeakPolarHBondContact CA-OG1 3.31Å; L210-T213 PolarHBondContact O-N 3.5Å; L210-T213 PolarHBondContact O-OG1 2.69Å; L211-T213 VanDerWaalsContact C-N 3.33Å; T213-Y217 WeakPolarHBondContact O-CB 3.29Å; T213-Y217 PolarHBondContact O-N 2.94Å
214	D	36.5	Very low	40.1	Very low	109 Å²	109	112.5 Å²	112.5	58%	0.583	58%	0.58	S	S	*	*	H	α-helix	trans	-66.3	-38.7	172.5	-86	-22.1	0	0	0	112	L210 Y217 V218	L210-D214 PolarHBondContact O-N 3.21Å; D214-Y217 PolarHBondContact O-N 2.89Å; D214-V218 WeakPolarHBondContact O-CG2 3.31Å; D214-V218 PolarHBondContact O-N 2.81Å; D214-V218 VanDerWaalsContact O-N 3.16Å
215	Y	34.6	Very low	39	Very low	165 Å²	165	117.6 Å²	117.6	65%	0.647	60%	0.603	S	S	*	*	H	α-helix	trans	-69.9	-40.9	177.6	-154	-94.1	0	0	0	112.2	L211 Y217 V218 V219	L211-Y215 VanDerWaalsContact O-CB 3.23Å; L211-Y215 WeakPolarHBondContact O-CB 3.44Å; L211-Y215 PolarHBondContact O-N 3.4Å; Y215-Y217 VanDerWaalsContact C-N 3.32Å; Y215-Y217 PolarHBondContact O-N 3.45Å; Y215-V218 PolarHBondContact O-N 2.69Å; Y215-V219 HydrophobicContact CD1-CG2 3.93Å; Y215-V219 HydrophobicContact CE1-CG2 3.88Å; Y215-V219 WeakPolarHBondContact O-CB 3.49Å; Y215-V219 VanDerWaalsContact O-CG2 3.25Å; Y215-V219 WeakPolarHBondContact O-CG2 3.35Å; Y215-V219 PolarHBondContact O-N 3.15Å
216	N	34.5	Very low	38.2	Very low	100 Å²	100	122.1 Å²	122.1	54%	0.535	62%	0.622	S	S	.	*	H	α-helix	trans	-68.5	-29.6	175.2	-79.7	-6.9	0	0	0	112.5	L212 Q220	L212-N216 WeakPolarHBondContact O-CB 3.31Å; L212-N216 VanDerWaalsContact O-CG 3.28Å; L212-N216 PolarHBondContact O-N 3.28Å; N216-Q220 WeakPolarHBondContact O-CB 3.45Å; N216-Q220 PolarHBondContact O-N 2.96Å
217	Y	36.5	Very low	37.3	Very low	183 Å²	183	124 Å²	124	72%	0.718	64%	0.635	S	S	*	*	H	α-helix	trans	-71.5	-35.7	175.8	-160.4	-97.1	0	0	0	112.2	T213 D214 Y215	T213-Y217 WeakPolarHBondContact O-CB 3.29Å; T213-Y217 PolarHBondContact O-N 2.94Å; D214-Y217 PolarHBondContact O-N 2.89Å; Y215-Y217 VanDerWaalsContact C-N 3.32Å; Y215-Y217 PolarHBondContact O-N 3.45Å
218	V	40.7	Very low	36.5	Very low	99 Å²	99	123.7 Å²	123.7	60%	0.6	66%	0.656	S	S	*	*	H	α-helix	trans	-73.4	-34.8	175.1	174.2	0	0	0	0	111.9	D214 Y215	D214-V218 WeakPolarHBondContact O-CG2 3.31Å; D214-V218 PolarHBondContact O-N 2.81Å; D214-V218 VanDerWaalsContact O-N 3.16Å; Y215-V218 PolarHBondContact O-N 2.69Å
219	V	38.2	Very low	35.8	Very low	69 Å²	69	126.4 Å²	126.4	42%	0.418	67%	0.672	S	S	.	*	H	α-helix	trans	-77.3	-29.5	179.3	174.1	0	0	0	0	112.6	Y215 H221 Q222	Y215-V219 HydrophobicContact CD1-CG2 3.93Å; Y215-V219 HydrophobicContact CE1-CG2 3.88Å; Y215-V219 WeakPolarHBondContact O-CB 3.49Å; Y215-V219 VanDerWaalsContact O-CG2 3.25Å; Y215-V219 WeakPolarHBondContact O-CG2 3.35Å; Y215-V219 PolarHBondContact O-N 3.15Å; V219-H221 VanDerWaalsContact C-N 3.27Å; V219-H221 PolarHBondContact O-N 2.86Å; V219-Q222 PolarHBondContact O-N 3.41Å
220	Q	31.5	Very low	35.2	Very low	147 Å²	147	126.1 Å²	126.1	69%	0.687	68%	0.68	S	S	*	*	H	α-helix	trans	-65.6	-27.6	179.4	-160.4	81.2	5.1	0	0	113.1	N216 Q222	N216-Q220 WeakPolarHBondContact O-CB 3.45Å; N216-Q220 PolarHBondContact O-N 2.96Å; Q220-Q222 VanDerWaalsContact C-N 3.32Å; Q220-Q222 PolarHBondContact O-N 3.48Å
221	H	32.6	Very low	34.5	Very low	170 Å²	170	127.7 Å²	127.7	79%	0.787	69%	0.694	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.2	-5.3	-177	-130.7	-70.7	0	0	0	114.2	V219	V219-H221 VanDerWaalsContact C-N 3.27Å; V219-H221 PolarHBondContact O-N 2.86Å
222	Q	30.9	Very low	34	Very low	177 Å²	177	125.9 Å²	125.9	83%	0.827	70%	0.704	S	S	*	*	S	Bend	trans	-122	3	-174.8	-140.6	160.5	-8.7	0	0	113.6	V219 Q220	V219-Q222 PolarHBondContact O-N 3.41Å; Q220-Q222 VanDerWaalsContact C-N 3.32Å; Q220-Q222 PolarHBondContact O-N 3.48Å
223	A	33.6	Very low	33	Very low	69 Å²	69	124.9 Å²	124.9	57%	0.57	72%	0.718	S	S	*	*			trans	-128.5	31.6	-174.4	0	0	0	0	0	114
224	V	36.2	Very low	32.5	Very low	126 Å²	126	129.1 Å²	129.1	76%	0.764	74%	0.737	S	S	*	*	S	Bend	trans	-87.4	-5.8	174.6	175.7	0	0	0	0	113.2
225	E	33.2	Very low	32.4	Very low	183 Å²	183	128.6 Å²	128.6	86%	0.855	75%	0.748	S	S	*	*	S	Bend	trans	-131.9	81.2	171.9	-75.4	-177.2	159.8	0	0	110.3
226	E	29.6	Very low	32.5	Very low	180 Å²	180	129.9 Å²	129.9	84%	0.841	76%	0.757	S	S	*	*	S	Bend	trans	164.1	134	133.3	-93.5	-180	150.5	0	0	111.5
227	S	26.9	Very low	32.7	Very low	116 Å²	116	129.4 Å²	129.4	81%	0.811	76%	0.761	S	S	*	*			trans	75	82.3	160.7	67.6	0	0	0	0	118.5	S229	S227-S229 PolarHBondContact O-N 2.93Å
228	A	32	Very low	33.2	Very low	102 Å²	102	126.9 Å²	126.9	84%	0.843	75%	0.754	S	S	*	*			trans	-60.5	118.3	141.5	0	0	0	0	0	109.8
229	S	28.4	Very low	34.2	Very low	103 Å²	103	127 Å²	127	72%	0.72	75%	0.751	S	S	*	*			trans	146.2	95.8	147.1	56.4	0	0	0	0	111.8	S227	S227-S229 PolarHBondContact O-N 2.93Å
230	T	26.3	Very low	34.9	Very low	139 Å²	139	129.6 Å²	129.6	85%	0.853	76%	0.757	S	S	*	*			trans	175.8	101.7	131.7	24.9	0	0	0	0	110.8
231	V	28.4	Very low	36.3	Very low	143 Å²	143	129 Å²	129	87%	0.867	76%	0.758	S	S	*	*			trans	31.3	103.8	138.6	-170.4	0	0	0	0	118.1
232	G	35.4	Very low	37.6	Very low	80 Å²	80	123 Å²	123	83%	0.825	74%	0.735	S	S	*	*				48.6	79.8	125.2	0	0	0	0	0	118.8
233	G	26.3	Very low	38.9	Very low	81 Å²	81	115.5 Å²	115.5	84%	0.835	70%	0.7	S	S	*	*			trans	-99.1	93.2	161.3	0	0	0	0	0	111.1	A235	G233-A235 PolarHBondContact O-N 3.21Å
234	L	30.4	Very low	39.9	Very low	171 Å²	171	114.4 Å²	114.4	90%	0.895	69%	0.685	S	S	*	*			trans	-54.4	121.5	172.9	-174.5	68.7	0	0	0	110.2	K236	L234-K236 PolarHBondContact O-N 3.34Å
235	A	34.5	Very low	41.1	Very low	97 Å²	97	114.2 Å²	114.2	80%	0.802	68%	0.679	S	S	*	*			trans	-52.1	104	173.7	0	0	0	0	0	110.3	G233 S237	G233-A235 PolarHBondContact O-N 3.21Å; A235-S237 PolarHBondContact O-N 3.47Å
236	K	35.8	Very low	42.3	Very low	193 Å²	193	108.9 Å²	108.9	84%	0.839	65%	0.654	S	S	*	*			trans	-75	109.7	-178.3	-151.8	172.4	-174.4	174.6	0	108	L234 K238	L234-K236 PolarHBondContact O-N 3.34Å; K236-K238 PolarHBondContact O-N 3.5Å
237	S	40.4	Very low	43.5	Very low	89 Å²	89	100.6 Å²	100.6	62%	0.622	62%	0.616	S	S	*	*			trans	-48.8	126	172.8	56.8	0	0	0	0	109.2	A235 D239	A235-S237 PolarHBondContact O-N 3.47Å; S237-D239 PolarHBondContact O-N 3.48Å
238	K	45.4	Very low	44.9	Very low	131 Å²	131	98.3 Å²	98.3	57%	0.57	59%	0.594	S	S	*	*			trans	-57.9	109.8	169	-124.1	172	175	-179.2	0	106.7	K236 F240 L243	K236-K238 PolarHBondContact O-N 3.5Å; K238-F240 PolarHBondContact O-N 3.44Å; K238-L243 HydrophobicContact CB-CG 4.47Å; K238-L243 HydrophobicContact CD-CD2 4.2Å
239	D	61.3	Low	46.1	Very low	100 Å²	100	98.4 Å²	98.4	54%	0.535	58%	0.576	S	S	.	*			trans	-56.3	131.5	-172.3	-68	-41.2	0	0	0	109.5	S237 L241 S242 L243	S237-D239 PolarHBondContact O-N 3.48Å; D239-L241 PolarHBondContact O-N 2.94Å; D239-S242 WeakPolarHBondContact O-CA 3.27Å; D239-S242 WeakPolarHBondContact O-CB 3.29Å; D239-S242 PolarHBondContact O-N 3.39Å; D239-S242 PolarHBondContact O-OG 3.49Å; D239-L243 PolarHBondContact O-N 2.89Å
240	F	54.6	Low	47.4	Very low	125 Å²	125	95.5 Å²	95.5	55%	0.548	55%	0.55	S	S	.	*	H	α-helix	trans	-47.3	-31.4	-179.1	175.6	-102.1	0	0	0	113.5	V197 K238 L243 L244	V197-F240 HydrophobicContact CG1-CE2 3.74Å; V197-F240 HydrophobicContact CG1-CZ 3.83Å; K238-F240 PolarHBondContact O-N 3.44Å; F240-L243 PolarHBondContact O-N 3.47Å; F240-L244 HydrophobicContact CD1-CD1 3.81Å; F240-L244 HydrophobicContact CE1-CD1 3.31Å; F240-L244 HydrophobicContact CE1-CG 4.13Å; F240-L244 HydrophobicContact CZ-CD1 3.88Å; F240-L244 HydrophobicContact CZ-CG 4.3Å; F240-L244 WeakPolarHBondContact O-CB 3.3Å; F240-L244 PolarHBondContact O-N 2.98Å
241	L	59.8	Low	48.7	Very low	134 Å²	134	89 Å²	89	70%	0.702	51%	0.511	S	S	*	.	H	α-helix	trans	-66.6	-37.8	173.5	-74	175.7	0	0	0	113.7	D239 L243 L244 L245	D239-L241 PolarHBondContact O-N 2.94Å; L241-L243 VanDerWaalsContact C-N 3.32Å; L241-L244 HydrophobicContact CD2-CD1 4.45Å; L241-L244 PolarHBondContact O-N 3.29Å; L241-L245 VanDerWaalsContact O-CB 3.23Å; L241-L245 WeakPolarHBondContact O-CB 3.44Å; L241-L245 PolarHBondContact O-N 2.91Å
242	S	60.3	Low	49.8	Very low	44 Å²	44	85.3 Å²	85.3	31%	0.308	48%	0.483	S	S	.	.	H	α-helix	trans	-65.9	-37.9	173.5	71.6	0	0	0	0	111.1	D239 L245 E246	D239-S242 WeakPolarHBondContact O-CA 3.27Å; D239-S242 WeakPolarHBondContact O-CB 3.29Å; D239-S242 PolarHBondContact O-N 3.39Å; D239-S242 PolarHBondContact O-OG 3.49Å; S242-L245 PolarHBondContact O-N 3.04Å; S242-E246 VanDerWaalsContact O-CB 3.3Å; S242-E246 WeakPolarHBondContact O-CB 3.47Å; S242-E246 PolarHBondContact O-N 2.89Å
243	L	57.8	Low	50.6	Low	20 Å²	20	84.5 Å²	84.5	11%	0.105	46%	0.459	C	S	.	.	H	α-helix	trans	-70.8	-37.6	174.8	-65.6	174.8	0	0	0	112.3	K238 D239 F240 L241 E246 S247	K238-L243 HydrophobicContact CB-CG 4.47Å; K238-L243 HydrophobicContact CD-CD2 4.2Å; D239-L243 PolarHBondContact O-N 2.89Å; F240-L243 PolarHBondContact O-N 3.47Å; L241-L243 VanDerWaalsContact C-N 3.32Å; L243-E246 PolarHBondContact O-N 2.93Å; L243-S247 WeakPolarHBondContact O-CB 2.99Å; L243-S247 PolarHBondContact O-N 3.23Å
244	L	54.5	Low	51.8	Low	46 Å²	46	82.3 Å²	82.3	24%	0.241	43%	0.429	C	S	.	.	H	α-helix	trans	-63.6	-42.7	171.3	-104.7	170.4	0	0	0	111.5	V197 F240 L241 S247 L248	V197-L244 HydrophobicContact CB-CD2 4.36Å; V197-L244 HydrophobicContact CG1-CD2 3.95Å; V197-L244 HydrophobicContact CG1-CG 3.94Å; V197-L244 HydrophobicContact CG2-CD2 3.5Å; V197-L244 HydrophobicContact CG2-CG 4.39Å; F240-L244 HydrophobicContact CD1-CD1 3.81Å; F240-L244 HydrophobicContact CE1-CD1 3.31Å; F240-L244 HydrophobicContact CE1-CG 4.13Å; F240-L244 HydrophobicContact CZ-CD1 3.88Å; F240-L244 HydrophobicContact CZ-CG 4.3Å; F240-L244 WeakPolarHBondContact O-CB 3.3Å; F240-L244 PolarHBondContact O-N 2.98Å; L241-L244 HydrophobicContact CD2-CD1 4.45Å; L241-L244 PolarHBondContact O-N 3.29Å; L244-S247 PolarHBondContact O-N 3.48Å; L244-L248 WeakPolarHBondContact O-CB 3.27Å; L244-L248 VanDerWaalsContact O-CG 3.25Å; L244-L248 WeakPolarHBondContact O-CG 3.38Å; L244-L248 PolarHBondContact O-N 2.92Å
245	L	61.3	Low	52.6	Low	121 Å²	121	78 Å²	78	63%	0.634	42%	0.417	S	S	*	.	H	α-helix	trans	-68.5	-40.2	177.7	-172.9	70.9	0	0	0	111	L241 S242 K249	L241-L245 VanDerWaalsContact O-CB 3.23Å; L241-L245 WeakPolarHBondContact O-CB 3.44Å; L241-L245 PolarHBondContact O-N 2.91Å; S242-L245 PolarHBondContact O-N 3.04Å; L245-K249 WeakPolarHBondContact O-CB 3.41Å; L245-K249 PolarHBondContact O-N 3.02Å
246	E	59.1	Low	53.5	Low	71 Å²	71	75.9 Å²	75.9	33%	0.332	40%	0.395	S	S	.	.	H	α-helix	trans	-65.6	-42.1	174.2	-153.8	92.8	-118.7	0	0	110.4	S242 L243 K249 E250	S242-E246 VanDerWaalsContact O-CB 3.3Å; S242-E246 WeakPolarHBondContact O-CB 3.47Å; S242-E246 PolarHBondContact O-N 2.89Å; L243-E246 PolarHBondContact O-N 2.93Å; E246-K249 CarbonylContact O-C 3.59Å; E246-K249 WeakPolarHBondContact O-CB 3.18Å; E246-K249 PolarHBondContact O-N 3.23Å; E246-K249 IonicContact OE1-NZ 3.81Å; E246-K249 PolarHBondContact OE1-NZ 2.65Å; E246-E250 WeakPolarHBondContact O-CB 3.29Å; E246-E250 VanDerWaalsContact O-CG 3.32Å; E246-E250 WeakPolarHBondContact O-CG 3.43Å; E246-E250 PolarHBondContact O-N 2.85Å
247	S	55.4	Low	54.5	Low	7 Å²	7	72.3 Å²	72.3	5%	0.049	39%	0.391	C	S	.	.	H	α-helix	trans	-63.4	-45.7	175.4	-178.1	0	0	0	0	111.6	Y196 L243 L244 K249 E250 Q251	Y196-S247 VanDerWaalsContact CD1-OG 3.32Å; Y196-S247 WeakPolarHBondContact CD1-OG 3.37Å; Y196-S247 WeakPolarHBondContact CE1-OG 3.43Å; L243-S247 WeakPolarHBondContact O-CB 2.99Å; L243-S247 PolarHBondContact O-N 3.23Å; L244-S247 PolarHBondContact O-N 3.48Å; S247-K249 VanDerWaalsContact C-N 3.34Å; S247-E250 WeakPolarHBondContact O-CB 3.39Å; S247-E250 PolarHBondContact O-N 3.01Å; S247-Q251 WeakPolarHBondContact O-CG 3.35Å; S247-Q251 PolarHBondContact O-N 3.43Å
248	L	55.4	Low	55.4	Low	67 Å²	67	71.6 Å²	71.6	35%	0.351	38%	0.38	S	S	.	.	H	α-helix	trans	-62.1	-42.6	171.5	-74.8	170.2	0	0	0	110.7	F193 L244 E250 Q251 F252	F193-L248 HydrophobicContact CE1-CD2 4.43Å; L244-L248 WeakPolarHBondContact O-CB 3.27Å; L244-L248 VanDerWaalsContact O-CG 3.25Å; L244-L248 WeakPolarHBondContact O-CG 3.38Å; L244-L248 PolarHBondContact O-N 2.92Å; L248-E250 VanDerWaalsContact C-N 3.32Å; L248-E250 PolarHBondContact O-N 3.38Å; L248-Q251 WeakPolarHBondContact O-CA 3.46Å; L248-Q251 WeakPolarHBondContact O-CB 3.43Å; L248-Q251 PolarHBondContact O-N 2.83Å; L248-F252 WeakPolarHBondContact O-CD2 3.49Å; L248-F252 PolarHBondContact O-N 2.97Å
249	K	56.8	Low	56.2	Low	105 Å²	105	68.1 Å²	68.1	46%	0.457	37%	0.37	S	S	.	.	H	α-helix	trans	-64	-35.8	177.1	178.5	179.5	172.9	-160.1	0	112.1	L245 E246 S247 F252 N253	L245-K249 WeakPolarHBondContact O-CB 3.41Å; L245-K249 PolarHBondContact O-N 3.02Å; E246-K249 CarbonylContact O-C 3.59Å; E246-K249 WeakPolarHBondContact O-CB 3.18Å; E246-K249 PolarHBondContact O-N 3.23Å; E246-K249 IonicContact OE1-NZ 3.81Å; E246-K249 PolarHBondContact OE1-NZ 2.65Å; S247-K249 VanDerWaalsContact C-N 3.34Å; K249-F252 CarbonylContact O-C 3.5Å; K249-F252 PolarHBondContact O-N 2.95Å; K249-N253 VanDerWaalsContact CG-ND2 3.28Å; K249-N253 WeakPolarHBondContact CG-ND2 3.47Å; K249-N253 WeakPolarHBondContact O-CB 3.5Å; K249-N253 PolarHBondContact O-N 3.04Å; K249-N253 PolarHBondContact O-ND2 2.61Å
250	E	57.1	Low	56	Low	41 Å²	41	69.1 Å²	69.1	19%	0.192	38%	0.38	C	S	.	.	H	α-helix	trans	-66.8	-38.1	169.7	-75.1	174.6	176.2	0	0	111.4	E246 S247 L248 F252 N253 H283	E246-E250 WeakPolarHBondContact O-CB 3.29Å; E246-E250 VanDerWaalsContact O-CG 3.32Å; E246-E250 WeakPolarHBondContact O-CG 3.43Å; E246-E250 PolarHBondContact O-N 2.85Å; S247-E250 WeakPolarHBondContact O-CB 3.39Å; S247-E250 PolarHBondContact O-N 3.01Å; L248-E250 VanDerWaalsContact C-N 3.32Å; L248-E250 PolarHBondContact O-N 3.38Å; E250-F252 PolarHBondContact O-N 3.15Å; E250-N253 PolarHBondContact O-N 2.92Å; E250-H283 IonicContact OE1-CE1 3.42Å
251	Q	52.1	Low	56.3	Low	4 Å²	4	65.1 Å²	65.1	2%	0.019	36%	0.363	C	S	.	.	H	α-helix	trans	-60.4	-27.8	171.9	-68.2	-71.9	-67.5	0	0	113.2	Y196 S247 L248	Y196-Q251 HydrophobicContact CE1-CG 4.26Å; S247-Q251 WeakPolarHBondContact O-CG 3.35Å; S247-Q251 PolarHBondContact O-N 3.43Å; L248-Q251 WeakPolarHBondContact O-CA 3.46Å; L248-Q251 WeakPolarHBondContact O-CB 3.43Å; L248-Q251 PolarHBondContact O-N 2.83Å
252	F	52.2	Low	56.3	Low	65 Å²	65	62.8 Å²	62.8	29%	0.285	36%	0.358	S	S	.	.	H	α-helix	trans	-94.1	-31.7	178.2	-70.9	-69.3	0	0	0	112.3	R131 W135 L248 K249 E250 N254	R131-F252 HydrophobicContact CB-CE1 4.09Å; R131-F252 HydrophobicContact CG-CE1 4.38Å; W135-F252 HydrophobicContact CB-CD1 4.12Å; W135-F252 HydrophobicContact CD2-CB 3.73Å; W135-F252 HydrophobicContact CD2-CD1 4.36Å; W135-F252 HydrophobicContact CD2-CG 4.38Å; W135-F252 HydrophobicContact CE3-CB 4.01Å; W135-F252 HydrophobicContact CE3-CD1 4.22Å; W135-F252 HydrophobicContact CE3-CG 4.25Å; W135-F252 HydrophobicContact CG-CB 4.01Å; W135-F252 HydrophobicContact CG-CD1 4.35Å; W135-F252 HydrophobicContact CZ2-CB 4.37Å; W135-F252 HydrophobicContact CZ3-CB 4.44Å; W135-F252 PolarHBondContact NE1-O 3.13Å; L248-F252 WeakPolarHBondContact O-CD2 3.49Å; L248-F252 PolarHBondContact O-N 2.97Å; K249-F252 CarbonylContact O-C 3.5Å; K249-F252 PolarHBondContact O-N 2.95Å; E250-F252 PolarHBondContact O-N 3.15Å; F252-N254 PolarHBondContact O-N 3.3Å
253	N	53	Low	56.5	Low	62 Å²	62	63.9 Å²	63.9	33%	0.332	37%	0.365	S	S	.	.			trans	-88.7	100.9	-171.5	-78.7	-22.5	0	0	0	114.7	W135 K249 E250 A255	W135-N253 VanDerWaalsContact CZ2-OD1 3.3Å; W135-N253 WeakPolarHBondContact CZ2-OD1 3.39Å; W135-N253 PolarHBondContact NE1-OD1 3.24Å; K249-N253 VanDerWaalsContact CG-ND2 3.28Å; K249-N253 WeakPolarHBondContact CG-ND2 3.47Å; K249-N253 WeakPolarHBondContact O-CB 3.5Å; K249-N253 PolarHBondContact O-N 3.04Å; K249-N253 PolarHBondContact O-ND2 2.61Å; E250-N253 PolarHBondContact O-N 2.92Å; N253-A255 PolarHBondContact O-N 3.37Å
254	N	51.6	Low	56.9	Low	36 Å²	36	63.9 Å²	63.9	19%	0.193	37%	0.366	C	S	.	.			trans	-85.2	5.5	174.3	-72.2	-43.7	0	0	0	115.5	E76 R132 F252	E76-N254 PolarHBondContact OE1-ND2 3.45Å; R132-N254 PolarHBondContact NH2-OD1 3.33Å; F252-N254 PolarHBondContact O-N 3.3Å
255	A	45.8	Very low	57.4	Low	79 Å²	79	69.7 Å²	69.7	65%	0.653	40%	0.397	S	S	*	.			trans	-134.6	72.6	-166.6	0	0	0	0	0	113.5	N253	N253-A255 PolarHBondContact O-N 3.37Å
256	T	53.2	Low	58.1	Low	54 Å²	54	66 Å²	66	33%	0.331	38%	0.381	S	S	.	.	P	Polyproline II helix	trans	-71.6	124.4	156.8	45.9	0	0	0	0	108.6	I258 R284	T256-I258 PolarHBondContact O-N 2.61Å; T256-R284 PolarHBondContact O-NH2 3.49Å; T256-R284 PolarHBondContact OG1-NH1 3.1Å; T256-R284 PolarHBondContact OG1-NH2 2.98Å
257	P	57.8	Low	58.9	Low	117 Å²	117	63.3 Å²	63.3	76%	0.76	37%	0.37	S	S	*	.	P	Polyproline II helix	trans	-58	136.1	179.8	23.2	-31.6	0	0	0	109.8	P259	P257-P259 VanDerWaalsContact O-CD 3.3Å; P257-P259 WeakPolarHBondContact O-CD 3.37Å
258	I	59.6	Low	60.2	Low	75 Å²	75	66.6 Å²	66.6	39%	0.385	39%	0.387	S	S	.	.	P	Polyproline II helix	trans	-63.1	121.4	176.1	-64.4	165.9	0	0	0	107.2	T256 T260 P339 Y342 L345	T256-I258 PolarHBondContact O-N 2.61Å; I258-T260 PolarHBondContact O-N 2.74Å; I258-P339 HydrophobicContact CD1-CG 4.04Å; I258-Y342 HydrophobicContact CG2-CD2 4.29Å; I258-L345 HydrophobicContact CG2-CD2 4.09Å
259	P	60.9	Low	61.4	Low	57 Å²	57	68.2 Å²	68.2	37%	0.37	40%	0.395	S	S	.	.	P	Polyproline II helix	trans	-59.1	135.3	176	-22.6	33.4	0	0	0	110.5	P257 L277 L345	P257-P259 VanDerWaalsContact O-CD 3.3Å; P257-P259 WeakPolarHBondContact O-CD 3.37Å; P259-L277 HydrophobicContact CB-CD2 4.46Å; P259-L277 HydrophobicContact CG-CD2 4.3Å; P259-L345 HydrophobicContact CB-CD2 4.28Å; P259-L345 WeakPolarHBondContact O-CD2 3.49Å
260	T	57.3	Low	62.6	Low	121 Å²	121	63.3 Å²	63.3	74%	0.742	37%	0.374	S	S	*	.	P	Polyproline II helix	trans	-77.7	127.2	175.4	47.7	0	0	0	0	109.8	I258 S262	I258-T260 PolarHBondContact O-N 2.74Å; T260-S262 PolarHBondContact O-N 2.95Å
261	H	61.5	Low	63.9	Low	41 Å²	41	62.5 Å²	62.5	19%	0.19	37%	0.369	C	S	.	.	P	Polyproline II helix	trans	-66.4	118.5	173.9	-169.8	-98.1	0	0	0	110	H61 C263 E273 L345 S349 H352	H61-H261 AromaticContact NE2-CE1 3.83Å; H261-C263 PolarHBondContact CE1-SG 3.19Å; H261-C263 PolarHBondContact ND1-N 3.09Å; H261-C263 PolarHBondContact ND1-SG 3.49Å; H261-E273 IonicContact CD2-OE1 3.17Å; H261-E273 PolarHBondContact CD2-OE1 3.46Å; H261-E273 IonicContact CG-OE1 3.89Å; H261-E273 IonicContact NE2-OE1 3.86Å; H261-L345 HydrophobicContact CB-CD1 3.44Å; H261-L345 VanDerWaalsContact CB-CD1 3.44Å; H261-S349 PolarHBondContact CD2-OG 3.33Å; H261-H352 AromaticContact CE1-CD2 3.67Å; H261-H352 AromaticContact CE1-NE2 3.54Å; H261-H352 AromaticContact NE2-CD2 3.56Å; H261-H352 AromaticContact NE2-NE2 3.92Å
262	S	59.2	Low	65.5	Low	85 Å²	85	67 Å²	67	59%	0.594	39%	0.393	S	S	*	.			trans	-110.9	73.6	176.6	-66	0	0	0	0	108.6	T260 P264	T260-S262 PolarHBondContact O-N 2.95Å; S262-P264 WeakPolarHBondContact O-CA 3.35Å; S262-P264 WeakPolarHBondContact O-CD 3.34Å; S262-P264 WeakPolarHBondContact O-CG 3.32Å
263	C	64.7	Low	67	Low	68 Å²	68	65.3 Å²	65.3	46%	0.459	39%	0.386	S	S	.	.			trans	-29.5	88.1	-174.9	-62.2	0	0	0	0	112.9	H61 H261	H61-C263 PolarHBondContact NE2-SG 2.86Å; H61-C263 VanDerWaalsContact NE2-SG 3.37Å; H261-C263 PolarHBondContact CE1-SG 3.19Å; H261-C263 PolarHBondContact ND1-N 3.09Å; H261-C263 PolarHBondContact ND1-SG 3.49Å
264	P	65.9	Low	68.6	Low	20 Å²	20	62.4 Å²	62.4	13%	0.13	37%	0.371	C	S	.	.			trans	-80.7	134.8	-165.9	-2.4	15.8	0	0	0	108.2	S262 S266 L269 I270 E273	S262-P264 WeakPolarHBondContact O-CA 3.35Å; S262-P264 WeakPolarHBondContact O-CD 3.34Å; S262-P264 WeakPolarHBondContact O-CG 3.32Å; P264-S266 VanDerWaalsContact C-N 3.33Å; P264-L269 HydrophobicContact CB-CB 3.62Å; P264-L269 HydrophobicContact CB-CD1 4.38Å; P264-L269 HydrophobicContact CG-CB 4.27Å; P264-I270 HydrophobicContact CB-CG1 4.02Å; P264-I270 HydrophobicContact CG-CG1 3.89Å; P264-I270 WeakPolarHBondContact O-CD1 3.28Å; P264-E273 WeakPolarHBondContact CD-OE2 3.37Å; P264-E273 VanDerWaalsContact CG-OE2 3.26Å; P264-E273 WeakPolarHBondContact CG-OE2 3.15Å
265	L	65.6	Low	70.2	Confident	168 Å²	168	63.9 Å²	63.9	88%	0.88	38%	0.377	S	S	*	.	S	Bend	trans	-80.5	-16.9	177	-75.2	151.6	0	0	0	112.3
266	S	75.7	Confident	72.1	Confident	44 Å²	44	63.8 Å²	63.8	31%	0.308	37%	0.37	S	S	.	.	S	Bend	trans	-96.5	136.9	-179.3	66.8	0	0	0	0	112.8	P264 D268 L269 I270	P264-S266 VanDerWaalsContact C-N 3.33Å; S266-D268 VanDerWaalsContact C-N 3.3Å; S266-D268 PolarHBondContact O-N 3.33Å; S266-L269 PolarHBondContact O-N 3.42Å; S266-L269 VanDerWaalsContact OG-CB 3.3Å; S266-L269 WeakPolarHBondContact OG-CB 3.44Å; S266-L269 WeakPolarHBondContact OG-CD1 3.43Å; S266-L269 WeakPolarHBondContact OG-CG 3.42Å; S266-I270 WeakPolarHBondContact O-CG1 2.94Å; S266-I270 PolarHBondContact O-N 3.04Å
267	P	77.1	Confident	73.6	Confident	13 Å²	13	61.4 Å²	61.4	8%	0.084	36%	0.355	C	S	.	.	H	α-helix	trans	-53.3	-41	177.5	-32.6	39.4	0	0	0	114.8	I270 R271 E374 I377 V399	P267-I270 PolarHBondContact O-N 3.19Å; P267-R271 WeakPolarHBondContact O-CG 3.36Å; P267-R271 PolarHBondContact O-N 2.93Å; P267-R271 VanDerWaalsContact O-N 3.09Å; P267-E374 WeakPolarHBondContact CB-O 3.21Å; P267-I377 HydrophobicContact CG-CD1 4.48Å; P267-I377 HydrophobicContact CG-CG1 3.75Å; P267-V399 HydrophobicContact CB-CG1 3.77Å; P267-V399 VanDerWaalsContact O-CG1 3.31Å; P267-V399 WeakPolarHBondContact O-CG1 3.46Å
268	D	81.4	Confident	75	Confident	77 Å²	77	57.9 Å²	57.9	41%	0.412	33%	0.328	S	S	.	.	H	α-helix	trans	-72.8	-35.5	-175.2	-55.8	-43.8	0	0	0	112.3	S266 R271 N272	S266-D268 VanDerWaalsContact C-N 3.3Å; S266-D268 PolarHBondContact O-N 3.33Å; D268-R271 PolarHBondContact O-N 3.25Å; D268-R271 IonicContact OD1-NH1 3.92Å; D268-R271 PolarHBondContact OD1-NH1 3.29Å; D268-N272 WeakPolarHBondContact O-CB 3.3Å; D268-N272 PolarHBondContact O-N 3.21Å
269	L	81.8	Confident	76	Confident	100 Å²	100	55.2 Å²	55.2	52%	0.524	32%	0.317	S	S	.	.	H	α-helix	trans	-67.1	-39	173.8	-69.9	177.6	0	0	0	111.4	P264 S266 R271 N272 E273	P264-L269 HydrophobicContact CB-CB 3.62Å; P264-L269 HydrophobicContact CB-CD1 4.38Å; P264-L269 HydrophobicContact CG-CB 4.27Å; S266-L269 PolarHBondContact O-N 3.42Å; S266-L269 VanDerWaalsContact OG-CB 3.3Å; S266-L269 WeakPolarHBondContact OG-CB 3.44Å; S266-L269 WeakPolarHBondContact OG-CD1 3.43Å; S266-L269 WeakPolarHBondContact OG-CG 3.42Å; L269-R271 VanDerWaalsContact C-N 3.34Å; L269-R271 PolarHBondContact O-N 3.1Å; L269-N272 PolarHBondContact O-N 3.19Å; L269-E273 WeakPolarHBondContact O-CB 3.35Å; L269-E273 PolarHBondContact O-N 3.09Å
270	I	81.7	Confident	77.1	Confident	2 Å²	2	54 Å²	54	1%	0.01	31%	0.308	C	S	.	.	H	α-helix	trans	-61.4	-43.6	175.1	-64.2	165.2	0	0	0	110.6	P264 S266 P267 E273 V274 H352 V399	P264-I270 HydrophobicContact CB-CG1 4.02Å; P264-I270 HydrophobicContact CG-CG1 3.89Å; P264-I270 WeakPolarHBondContact O-CD1 3.28Å; S266-I270 WeakPolarHBondContact O-CG1 2.94Å; S266-I270 PolarHBondContact O-N 3.04Å; P267-I270 PolarHBondContact O-N 3.19Å; I270-E273 PolarHBondContact O-N 3.35Å; I270-V274 WeakPolarHBondContact O-CG2 3.45Å; I270-V274 PolarHBondContact O-N 3.3Å; I270-H352 HydrophobicContact CD1-CB 4.37Å; I270-H352 HydrophobicContact CG2-CB 3.96Å; I270-V399 HydrophobicContact CB-CG1 4.32Å; I270-V399 HydrophobicContact CD1-CG2 4.16Å; I270-V399 HydrophobicContact CG2-CG1 4.38Å
271	R	84.3	Confident	78.5	Confident	24 Å²	24	49.3 Å²	49.3	9%	0.091	28%	0.277	C	S	.	.	H	α-helix	trans	-63.8	-45.8	177.1	-68.6	179.5	-167.4	115.8	4.8	111.6	P267 D268 L269 E273 V274 E275 E374 V399	P267-R271 WeakPolarHBondContact O-CG 3.36Å; P267-R271 PolarHBondContact O-N 2.93Å; P267-R271 VanDerWaalsContact O-N 3.09Å; D268-R271 PolarHBondContact O-N 3.25Å; D268-R271 IonicContact OD1-NH1 3.92Å; D268-R271 PolarHBondContact OD1-NH1 3.29Å; L269-R271 VanDerWaalsContact C-N 3.34Å; L269-R271 PolarHBondContact O-N 3.1Å; R271-E273 PolarHBondContact O-N 3.16Å; R271-V274 PolarHBondContact O-N 3.2Å; R271-E275 WeakPolarHBondContact O-CG 3.12Å; R271-E275 PolarHBondContact O-N 3.39Å; R271-E374 VanDerWaalsContact CZ-O 3.24Å; R271-E374 PolarHBondContact NH1-O 2.92Å; R271-E374 PolarHBondContact NH2-O 3.27Å; R271-V399 HydrophobicContact CG-CG1 3.95Å; R271-V399 VanDerWaalsContact CZ-O 3.27Å; R271-V399 PolarHBondContact NE-O 3.03Å; R271-V399 PolarHBondContact NH2-O 3.27Å
272	N	84.8	Confident	79.6	Confident	98 Å²	98	50.9 Å²	50.9	52%	0.524	29%	0.287	S	S	.	.	H	α-helix	trans	-63.2	-41.6	178.6	-169.7	20.7	0	0	0	111.8	D268 L269 V274 E275 C276	D268-N272 WeakPolarHBondContact O-CB 3.3Å; D268-N272 PolarHBondContact O-N 3.21Å; L269-N272 PolarHBondContact O-N 3.19Å; N272-V274 PolarHBondContact O-N 3.49Å; N272-E275 PolarHBondContact O-N 2.91Å; N272-C276 WeakPolarHBondContact O-CB 3.29Å; N272-C276 PolarHBondContact O-N 3.34Å; N272-C276 PolarHBondContact O-SG 2.87Å
273	E	85.1	Confident	80.7	Confident	31 Å²	31	50 Å²	50	15%	0.145	27%	0.273	C	S	.	.	H	α-helix	trans	-59	-46.5	174.2	-174.6	-177.2	-177.7	0	0	111.3	H261 P264 L269 I270 R271 E275 C276 L277 S349	H261-E273 IonicContact CD2-OE1 3.17Å; H261-E273 PolarHBondContact CD2-OE1 3.46Å; H261-E273 IonicContact CG-OE1 3.89Å; H261-E273 IonicContact NE2-OE1 3.86Å; P264-E273 WeakPolarHBondContact CD-OE2 3.37Å; P264-E273 VanDerWaalsContact CG-OE2 3.26Å; P264-E273 WeakPolarHBondContact CG-OE2 3.15Å; L269-E273 WeakPolarHBondContact O-CB 3.35Å; L269-E273 PolarHBondContact O-N 3.09Å; I270-E273 PolarHBondContact O-N 3.35Å; R271-E273 PolarHBondContact O-N 3.16Å; E273-E275 PolarHBondContact O-N 3.48Å; E273-C276 PolarHBondContact O-N 2.91Å; E273-L277 HydrophobicContact CG-CD1 3.95Å; E273-L277 HydrophobicContact CG-CG 4.41Å; E273-L277 WeakPolarHBondContact O-CB 3.33Å; E273-L277 VanDerWaalsContact O-CG 3.29Å; E273-L277 WeakPolarHBondContact O-CG 3.26Å; E273-L277 PolarHBondContact O-N 3.44Å; E273-S349 PolarHBondContact OE1-OG 3.3Å
274	V	85.7	Confident	81.7	Confident	0 Å²	0	47.1 Å²	47.1	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-62.5	-41	177.2	167.1	0	0	0	0	112	I270 R271 N272 L277 K278 L353 F410	I270-V274 WeakPolarHBondContact O-CG2 3.45Å; I270-V274 PolarHBondContact O-N 3.3Å; R271-V274 PolarHBondContact O-N 3.2Å; N272-V274 PolarHBondContact O-N 3.49Å; V274-L277 PolarHBondContact O-N 3.41Å; V274-K278 WeakPolarHBondContact O-CB 3.36Å; V274-K278 PolarHBondContact O-N 2.84Å; V274-L353 HydrophobicContact CG1-CD1 4.48Å; V274-L353 HydrophobicContact CG1-CD2 3.84Å; V274-L353 HydrophobicContact CG2-CB 4.18Å; V274-L353 HydrophobicContact CG2-CD1 4.2Å; V274-L353 HydrophobicContact CG2-CD2 4.2Å; V274-L353 HydrophobicContact CG2-CG 4.42Å; V274-F410 HydrophobicContact CG1-CD1 3.89Å; V274-F410 HydrophobicContact CG1-CD2 4.46Å; V274-F410 HydrophobicContact CG1-CE1 3.98Å; V274-F410 HydrophobicContact CG1-CG 4.14Å; V274-F410 HydrophobicContact CG1-CZ 4.32Å; V274-F410 HydrophobicContact CG2-CE1 4.16Å
275	E	86.2	Confident	82.7	Confident	68 Å²	68	48 Å²	48	32%	0.318	26%	0.256	S	S	.	.	H	α-helix	trans	-64	-44	176.8	-73.9	-57.9	129.9	0	0	111.8	R271 N272 E273 K278 A279 H407	R271-E275 WeakPolarHBondContact O-CG 3.12Å; R271-E275 PolarHBondContact O-N 3.39Å; N272-E275 PolarHBondContact O-N 2.91Å; E273-E275 PolarHBondContact O-N 3.48Å; E275-K278 PolarHBondContact O-N 3.34Å; E275-K278 IonicContact OE1-NZ 2.81Å; E275-K278 PolarHBondContact OE1-NZ 2.86Å; E275-K278 WeakPolarHBondContact OE2-CE 3.46Å; E275-K278 IonicContact OE2-NZ 3.45Å; E275-K278 PolarHBondContact OE2-NZ 2.9Å; E275-A279 WeakPolarHBondContact O-CB 3.34Å; E275-A279 PolarHBondContact O-N 2.98Å; E275-H407 IonicContact OE1-CD2 3.89Å; E275-H407 PolarHBondContact OE1-CD2 2.99Å; E275-H407 IonicContact OE1-NE2 2.61Å; E275-H407 PolarHBondContact OE1-NE2 3.06Å
276	C	84.3	Confident	83.6	Confident	76 Å²	76	44 Å²	44	51%	0.514	23%	0.232	S	C	.	.	H	α-helix	trans	-60.5	-47.7	173.4	-76.1	0	0	0	0	111.9	N272 E273 K278 A279 D280	N272-C276 WeakPolarHBondContact O-CB 3.29Å; N272-C276 PolarHBondContact O-N 3.34Å; N272-C276 PolarHBondContact O-SG 2.87Å; E273-C276 PolarHBondContact O-N 2.91Å; C276-K278 PolarHBondContact O-N 3.21Å; C276-A279 WeakPolarHBondContact O-CB 3.44Å; C276-A279 PolarHBondContact O-N 3.32Å; C276-D280 PolarHBondContact O-N 2.93Å
277	L	85.1	Confident	83.9	Confident	4 Å²	4	42.6 Å²	42.6	2%	0.021	22%	0.22	C	C	.	.	H	α-helix	trans	-65.8	-37.4	179	-73.5	174	0	0	0	112.6	P259 E273 V274 A279 D280 F281 L345 L346 S349 F410	P259-L277 HydrophobicContact CB-CD2 4.46Å; P259-L277 HydrophobicContact CG-CD2 4.3Å; E273-L277 HydrophobicContact CG-CD1 3.95Å; E273-L277 HydrophobicContact CG-CG 4.41Å; E273-L277 WeakPolarHBondContact O-CB 3.33Å; E273-L277 VanDerWaalsContact O-CG 3.29Å; E273-L277 WeakPolarHBondContact O-CG 3.26Å; E273-L277 PolarHBondContact O-N 3.44Å; V274-L277 PolarHBondContact O-N 3.41Å; L277-A279 VanDerWaalsContact C-N 3.33Å; L277-D280 PolarHBondContact O-N 3.42Å; L277-F281 VanDerWaalsContact O-CB 3.28Å; L277-F281 WeakPolarHBondContact O-CB 3.43Å; L277-F281 PolarHBondContact O-N 3.46Å; L277-L345 HydrophobicContact CD1-CG 4.33Å; L277-L345 HydrophobicContact CD2-CD2 3.66Å; L277-L345 HydrophobicContact CD2-CG 4.05Å; L277-L346 HydrophobicContact CB-CD2 3.83Å; L277-L346 HydrophobicContact CD1-CD2 4.36Å; L277-L346 HydrophobicContact CD2-CD2 4.37Å; L277-L346 HydrophobicContact CG-CD2 4.42Å; L277-S349 WeakPolarHBondContact CD1-OG 3.41Å; L277-F410 HydrophobicContact CB-CZ 4.49Å
278	K	86.4	Confident	84.5	Confident	43 Å²	43	42 Å²	42	19%	0.187	22%	0.216	C	C	.	.	H	α-helix	trans	-62.2	-43.1	173	-177.3	-179	74.6	-165.6	0	110.8	V274 E275 C276 N282 S406 F410	V274-K278 WeakPolarHBondContact O-CB 3.36Å; V274-K278 PolarHBondContact O-N 2.84Å; E275-K278 PolarHBondContact O-N 3.34Å; E275-K278 IonicContact OE1-NZ 2.81Å; E275-K278 PolarHBondContact OE1-NZ 2.86Å; E275-K278 WeakPolarHBondContact OE2-CE 3.46Å; E275-K278 IonicContact OE2-NZ 3.45Å; E275-K278 PolarHBondContact OE2-NZ 2.9Å; C276-K278 PolarHBondContact O-N 3.21Å; K278-N282 WeakPolarHBondContact O-CB 3.36Å; K278-N282 PolarHBondContact O-N 2.89Å; K278-N282 PolarHBondContact O-ND2 3.02Å; K278-N282 VanDerWaalsContact O-ND2 3.15Å; K278-S406 PolarHBondContact NZ-OG 2.82Å; K278-F410 HydrophobicContact CB-CD2 4.29Å; K278-F410 HydrophobicContact CB-CE2 4.48Å
279	A	81.8	Confident	84.9	Confident	20 Å²	20	41.4 Å²	41.4	17%	0.165	21%	0.212	C	C	.	.	H	α-helix	trans	-63.6	-45.8	177.4	0	0	0	0	0	111.9	R207 E275 C276 L277 N282 H283	R207-A279 VanDerWaalsContact NH2-CB 3.3Å; E275-A279 WeakPolarHBondContact O-CB 3.34Å; E275-A279 PolarHBondContact O-N 2.98Å; C276-A279 WeakPolarHBondContact O-CB 3.44Å; C276-A279 PolarHBondContact O-N 3.32Å; L277-A279 VanDerWaalsContact C-N 3.33Å; A279-N282 PolarHBondContact O-N 3.4Å; A279-H283 WeakPolarHBondContact O-CB 3.32Å; A279-H283 PolarHBondContact O-N 2.95Å
280	D	83.4	Confident	85.1	Confident	31 Å²	31	37.8 Å²	37.8	17%	0.166	19%	0.193	C	C	.	.	H	α-helix	trans	-64	-45.9	177.4	-177.4	58.5	0	0	0	111.6	C276 L277 N282 H283 R284 Y342	C276-D280 PolarHBondContact O-N 2.93Å; L277-D280 PolarHBondContact O-N 3.42Å; D280-N282 VanDerWaalsContact C-N 3.34Å; D280-N282 PolarHBondContact O-N 2.75Å; D280-H283 WeakPolarHBondContact O-CB 3.4Å; D280-H283 PolarHBondContact O-N 2.88Å; D280-H283 VanDerWaalsContact O-N 3.13Å; D280-R284 WeakPolarHBondContact O-CG 3.39Å; D280-R284 PolarHBondContact O-N 2.9Å; D280-R284 IonicContact OD1-CZ 3.15Å; D280-R284 IonicContact OD1-NE 3.58Å; D280-R284 PolarHBondContact OD1-NE 3.13Å; D280-R284 IonicContact OD1-NH2 3.87Å; D280-R284 IonicContact OD2-CZ 3.44Å; D280-R284 IonicContact OD2-NE 3.3Å; D280-R284 PolarHBondContact OD2-NE 3.45Å; D280-R284 IonicContact OD2-NH2 3.51Å; D280-R284 PolarHBondContact OD2-NH2 3.36Å; D280-Y342 WeakPolarHBondContact OD2-CE2 3.24Å; D280-Y342 VanDerWaalsContact OD2-CZ 3.24Å; D280-Y342 PolarHBondContact OD2-OH 2.79Å
281	F	86.1	Confident	85.4	Confident	23 Å²	23	37.8 Å²	37.8	10%	0.101	19%	0.192	C	C	.	.	H	α-helix	trans	-58	-46.3	175.6	174.6	-92.6	0	0	0	111.6	L277 H283 R284 I285 L338 Y342 L346 L413 F414	L277-F281 VanDerWaalsContact O-CB 3.28Å; L277-F281 WeakPolarHBondContact O-CB 3.43Å; L277-F281 PolarHBondContact O-N 3.46Å; F281-H283 VanDerWaalsContact C-N 3.3Å; F281-H283 PolarHBondContact O-N 3.31Å; F281-R284 PolarHBondContact O-N 3.46Å; F281-I285 HydrophobicContact CD1-CG1 4.18Å; F281-I285 HydrophobicContact CD2-CG1 4.45Å; F281-I285 HydrophobicContact CE1-CG1 3.73Å; F281-I285 HydrophobicContact CE2-CD1 4.26Å; F281-I285 HydrophobicContact CE2-CG1 4.05Å; F281-I285 HydrophobicContact CZ-CD1 4.01Å; F281-I285 HydrophobicContact CZ-CG1 3.65Å; F281-I285 WeakPolarHBondContact O-CG1 3.21Å; F281-I285 PolarHBondContact O-N 3.26Å; F281-L338 HydrophobicContact CD2-CD2 3.7Å; F281-L338 HydrophobicContact CE2-CD2 3.3Å; F281-L338 HydrophobicContact CZ-CD2 4.33Å; F281-Y342 WeakPolarHBondContact CA-OH 3.37Å; F281-Y342 HydrophobicContact CD2-CE1 4.35Å; F281-Y342 PolarHBondContact N-OH 2.83Å; F281-Y342 VanDerWaalsContact N-OH 3.15Å; F281-L346 HydrophobicContact CD2-CD1 3.92Å; F281-L413 HydrophobicContact CE1-CD2 4.11Å; F281-L413 HydrophobicContact CZ-CD2 3.85Å; F281-F414 HydrophobicContact CD1-CZ 4.18Å; F281-F414 HydrophobicContact CD2-CE1 4.11Å; F281-F414 AromaticContact CD2-CZ 3.63Å; F281-F414 HydrophobicContact CD2-CZ 3.63Å; F281-F414 HydrophobicContact CE1-CZ 4.13Å; F281-F414 AromaticContact CE2-CE1 3.81Å; F281-F414 HydrophobicContact CE2-CE1 3.81Å; F281-F414 AromaticContact CE2-CZ 3.54Å; F281-F414 HydrophobicContact CE2-CZ 3.54Å; F281-F414 AromaticContact CG-CZ 3.95Å; F281-F414 HydrophobicContact CG-CZ 3.95Å; F281-F414 HydrophobicContact CZ-CE1 4.32Å; F281-F414 AromaticContact CZ-CZ 3.83Å; F281-F414 HydrophobicContact CZ-CZ 3.83Å
282	N	85.9	Confident	85.8	Confident	74 Å²	74	36.6 Å²	36.6	40%	0.396	19%	0.188	S	C	.	.	H	α-helix	trans	-64.6	-35.4	178.1	-74.6	-28	0	0	0	112.3	K278 A279 D280 K286	K278-N282 WeakPolarHBondContact O-CB 3.36Å; K278-N282 PolarHBondContact O-N 2.89Å; K278-N282 PolarHBondContact O-ND2 3.02Å; K278-N282 VanDerWaalsContact O-ND2 3.15Å; A279-N282 PolarHBondContact O-N 3.4Å; D280-N282 VanDerWaalsContact C-N 3.34Å; D280-N282 PolarHBondContact O-N 2.75Å; N282-K286 VanDerWaalsContact O-CG 3.25Å; N282-K286 WeakPolarHBondContact O-CG 3.31Å; N282-K286 PolarHBondContact O-N 3.44Å; N282-K286 VanDerWaalsContact O-N 3.14Å
283	H	82.3	Confident	86.1	Confident	65 Å²	65	36.3 Å²	36.3	30%	0.301	19%	0.186	S	C	.	.	H	α-helix	trans	-66	-49.9	175	-178.8	77.7	0	0	0	110.8	E250 A279 D280 F281 I285 K286 E287	E250-H283 IonicContact OE1-CE1 3.42Å; A279-H283 WeakPolarHBondContact O-CB 3.32Å; A279-H283 PolarHBondContact O-N 2.95Å; D280-H283 WeakPolarHBondContact O-CB 3.4Å; D280-H283 PolarHBondContact O-N 2.88Å; D280-H283 VanDerWaalsContact O-N 3.13Å; F281-H283 VanDerWaalsContact C-N 3.3Å; F281-H283 PolarHBondContact O-N 3.31Å; H283-I285 VanDerWaalsContact C-N 3.35Å; H283-I285 PolarHBondContact O-N 2.86Å; H283-K286 WeakPolarHBondContact O-CB 3.45Å; H283-K286 PolarHBondContact O-N 3.01Å; H283-K286 VanDerWaalsContact O-N 3.13Å; H283-E287 PolarHBondContact O-N 3.29Å
284	R	86	Confident	86.4	Confident	9 Å²	9	35 Å²	35	3%	0.034	18%	0.18	C	C	.	.	H	α-helix	trans	-56.7	-44.5	176	-67.7	173.5	-173	-79	-6.7	112.4	T256 D280 F281 K286 E287 V288 L337 L338	T256-R284 PolarHBondContact O-NH2 3.49Å; T256-R284 PolarHBondContact OG1-NH1 3.1Å; T256-R284 PolarHBondContact OG1-NH2 2.98Å; D280-R284 WeakPolarHBondContact O-CG 3.39Å; D280-R284 PolarHBondContact O-N 2.9Å; D280-R284 IonicContact OD1-CZ 3.15Å; D280-R284 IonicContact OD1-NE 3.58Å; D280-R284 PolarHBondContact OD1-NE 3.13Å; D280-R284 IonicContact OD1-NH2 3.87Å; D280-R284 IonicContact OD2-CZ 3.44Å; D280-R284 IonicContact OD2-NE 3.3Å; D280-R284 PolarHBondContact OD2-NE 3.45Å; D280-R284 IonicContact OD2-NH2 3.51Å; D280-R284 PolarHBondContact OD2-NH2 3.36Å; F281-R284 PolarHBondContact O-N 3.46Å; R284-K286 PolarHBondContact O-N 3.36Å; R284-E287 WeakPolarHBondContact O-CB 3.18Å; R284-E287 PolarHBondContact O-N 2.89Å; R284-V288 VanDerWaalsContact O-CG2 3.31Å; R284-V288 WeakPolarHBondContact O-CG2 3.3Å; R284-V288 PolarHBondContact O-N 3.38Å; R284-L337 PolarHBondContact NH1-O 2.95Å; R284-L338 HydrophobicContact CB-CD1 4.26Å
285	I	86.4	Confident	86.7	Confident	37 Å²	37	35.3 Å²	35.3	19%	0.19	18%	0.182	C	C	.	.	H	α-helix	trans	-65	-38.2	178.5	-69.3	-64.6	0	0	0	112	F281 H283 V288 L289 L338	F281-I285 HydrophobicContact CD1-CG1 4.18Å; F281-I285 HydrophobicContact CD2-CG1 4.45Å; F281-I285 HydrophobicContact CE1-CG1 3.73Å; F281-I285 HydrophobicContact CE2-CD1 4.26Å; F281-I285 HydrophobicContact CE2-CG1 4.05Å; F281-I285 HydrophobicContact CZ-CD1 4.01Å; F281-I285 HydrophobicContact CZ-CG1 3.65Å; F281-I285 WeakPolarHBondContact O-CG1 3.21Å; F281-I285 PolarHBondContact O-N 3.26Å; H283-I285 VanDerWaalsContact C-N 3.35Å; H283-I285 PolarHBondContact O-N 2.86Å; I285-V288 PolarHBondContact O-N 3.42Å; I285-L289 HydrophobicContact CG2-CD1 4.02Å; I285-L289 HydrophobicContact CG2-CG 4.43Å; I285-L289 WeakPolarHBondContact O-CB 3.47Å; I285-L289 WeakPolarHBondContact O-CG 3.42Å; I285-L289 PolarHBondContact O-N 2.95Å; I285-L338 HydrophobicContact CD1-CD1 4Å; I285-L338 HydrophobicContact CD1-CD2 4.02Å
286	K	83.5	Confident	87.1	Confident	86 Å²	86	32.1 Å²	32.1	37%	0.374	17%	0.167	S	C	.	.	H	α-helix	trans	-64.7	-42.4	174.6	-74.7	171.9	-178.5	-177	0	111.8	H203 N282 H283 R284 L289 F290	H203-K286 PolarHBondContact CD2-NZ 3.33Å; H203-K286 PolarHBondContact CE1-NZ 3.22Å; H203-K286 PolarHBondContact ND1-NZ 3.3Å; H203-K286 PolarHBondContact NE2-NZ 2.93Å; N282-K286 VanDerWaalsContact O-CG 3.25Å; N282-K286 WeakPolarHBondContact O-CG 3.31Å; N282-K286 PolarHBondContact O-N 3.44Å; N282-K286 VanDerWaalsContact O-N 3.14Å; H283-K286 WeakPolarHBondContact O-CB 3.45Å; H283-K286 PolarHBondContact O-N 3.01Å; H283-K286 VanDerWaalsContact O-N 3.13Å; R284-K286 PolarHBondContact O-N 3.36Å; K286-L289 PolarHBondContact O-N 3.37Å; K286-F290 WeakPolarHBondContact O-CB 3.46Å; K286-F290 PolarHBondContact O-N 2.92Å
287	E	83.8	Confident	87.5	Confident	13 Å²	13	29.8 Å²	29.8	6%	0.061	15%	0.148	C	C	.	.	H	α-helix	trans	-60.4	-46.2	175.8	-170.1	-171.6	156.8	0	0	111	H283 R284 F290 N291 L337	H283-E287 PolarHBondContact O-N 3.29Å; R284-E287 WeakPolarHBondContact O-CB 3.18Å; R284-E287 PolarHBondContact O-N 2.89Å; E287-F290 PolarHBondContact O-N 3.47Å; E287-N291 VanDerWaalsContact O-CB 3.3Å; E287-N291 WeakPolarHBondContact O-CB 3.37Å; E287-N291 PolarHBondContact O-N 2.86Å; E287-N291 PolarHBondContact O-ND2 3.44Å; E287-L337 HydrophobicContact CB-CD2 3.98Å; E287-L337 VanDerWaalsContact CD-CD2 3.41Å; E287-L337 HydrophobicContact CG-CD2 3.89Å; E287-L337 WeakPolarHBondContact OE2-CD2 3.37Å
288	V	89.4	Confident	87.9	Confident	0 Å²	0	29.6 Å²	29.6	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-57.6	-50.1	173.8	169.4	0	0	0	0	111.4	R284 I285 F290 N291 S292 F330 L333 T334 L337 L338	R284-V288 VanDerWaalsContact O-CG2 3.31Å; R284-V288 WeakPolarHBondContact O-CG2 3.3Å; R284-V288 PolarHBondContact O-N 3.38Å; I285-V288 PolarHBondContact O-N 3.42Å; V288-F290 VanDerWaalsContact C-N 3.31Å; V288-F290 PolarHBondContact O-N 2.86Å; V288-N291 PolarHBondContact O-N 3.41Å; V288-S292 VanDerWaalsContact O-CB 3.3Å; V288-S292 WeakPolarHBondContact O-CB 3.48Å; V288-S292 PolarHBondContact O-N 2.75Å; V288-S292 PolarHBondContact O-OG 2.92Å; V288-F330 HydrophobicContact CG1-CD2 3.54Å; V288-F330 HydrophobicContact CG1-CE2 3.66Å; V288-F330 HydrophobicContact CG1-CG 4.32Å; V288-L333 HydrophobicContact CG1-CB 3.99Å; V288-L333 HydrophobicContact CG2-CB 4.3Å; V288-T334 WeakPolarHBondContact CG1-OG1 3.36Å; V288-L337 HydrophobicContact CG2-CB 3.86Å; V288-L337 HydrophobicContact CG2-CD1 4.32Å; V288-L337 HydrophobicContact CG2-CD2 3.79Å; V288-L337 HydrophobicContact CG2-CG 4.2Å; V288-L338 HydrophobicContact CG2-CD1 4.38Å
289	L	88.9	Confident	88.3	Confident	65 Å²	65	27.6 Å²	27.6	34%	0.34	14%	0.138	S	C	.	.	H	α-helix	trans	-60.9	-43.2	-179	-78.1	169.9	0	0	0	111.1	I285 K286 S292 L293 W326 F330	I285-L289 HydrophobicContact CG2-CD1 4.02Å; I285-L289 HydrophobicContact CG2-CG 4.43Å; I285-L289 WeakPolarHBondContact O-CB 3.47Å; I285-L289 WeakPolarHBondContact O-CG 3.42Å; I285-L289 PolarHBondContact O-N 2.95Å; K286-L289 PolarHBondContact O-N 3.37Å; L289-S292 WeakPolarHBondContact CA-OG 3.49Å; L289-S292 PolarHBondContact O-OG 3.32Å; L289-L293 WeakPolarHBondContact O-CB 3.36Å; L289-L293 WeakPolarHBondContact O-CD1 3.31Å; L289-L293 VanDerWaalsContact O-CG 3.24Å; L289-L293 WeakPolarHBondContact O-CG 3.41Å; L289-L293 PolarHBondContact O-N 3.13Å; L289-W326 HydrophobicContact CD2-CZ2 4.47Å; L289-F330 HydrophobicContact CD2-CD2 3.91Å; L289-F330 HydrophobicContact CD2-CE2 3.64Å; L289-F330 HydrophobicContact CG-CE2 4.12Å
290	F	86.1	Confident	88.8	Confident	25 Å²	25	26.6 Å²	26.6	11%	0.11	13%	0.13	C	C	.	.	H	α-helix	trans	-66.7	-50.8	178.4	179.7	-89.9	0	0	0	111.8	Y196 K286 E287 V288 S292 L293 F294	Y196-F290 VanDerWaalsContact CB-CE2 3.45Å; Y196-F290 HydrophobicContact CD1-CE2 4.24Å; Y196-F290 HydrophobicContact CD1-CZ 4.18Å; Y196-F290 HydrophobicContact CD2-CB 4.31Å; Y196-F290 HydrophobicContact CD2-CD1 4.23Å; Y196-F290 AromaticContact CD2-CD2 3.01Å; Y196-F290 HydrophobicContact CD2-CD2 3.01Å; Y196-F290 HydrophobicContact CD2-CE1 4.43Å; Y196-F290 AromaticContact CD2-CE2 3.24Å; Y196-F290 HydrophobicContact CD2-CE2 3.24Å; Y196-F290 AromaticContact CD2-CG 3.53Å; Y196-F290 HydrophobicContact CD2-CG 3.53Å; Y196-F290 AromaticContact CD2-CZ 3.94Å; Y196-F290 HydrophobicContact CD2-CZ 3.94Å; Y196-F290 HydrophobicContact CE2-CB 3.81Å; Y196-F290 AromaticContact CE2-CD1 3.95Å; Y196-F290 HydrophobicContact CE2-CD1 3.95Å; Y196-F290 AromaticContact CE2-CD2 3.39Å; Y196-F290 HydrophobicContact CE2-CD2 3.39Å; Y196-F290 HydrophobicContact CE2-CE1 4.48Å; Y196-F290 AromaticContact CE2-CE2 3.96Å; Y196-F290 HydrophobicContact CE2-CE2 3.96Å; Y196-F290 AromaticContact CE2-CG 3.34Å; Y196-F290 HydrophobicContact CE2-CG 3.34Å; Y196-F290 HydrophobicContact CE2-CZ 4.43Å; Y196-F290 AromaticContact CG-CD2 3.71Å; Y196-F290 HydrophobicContact CG-CD2 3.71Å; Y196-F290 HydrophobicContact CG-CE1 4.47Å; Y196-F290 AromaticContact CG-CE2 3.39Å; Y196-F290 HydrophobicContact CG-CE2 3.39Å; Y196-F290 HydrophobicContact CG-CG 4.32Å; Y196-F290 AromaticContact CG-CZ 3.78Å; Y196-F290 HydrophobicContact CG-CZ 3.78Å; K286-F290 WeakPolarHBondContact O-CB 3.46Å; K286-F290 PolarHBondContact O-N 2.92Å; E287-F290 PolarHBondContact O-N 3.47Å; V288-F290 VanDerWaalsContact C-N 3.31Å; V288-F290 PolarHBondContact O-N 2.86Å; F290-S292 VanDerWaalsContact C-N 3.31Å; F290-S292 PolarHBondContact O-N 3.43Å; F290-L293 PolarHBondContact O-N 3.14Å; F290-F294 HydrophobicContact CE1-CB 3.95Å; F290-F294 HydrophobicContact CE1-CD2 4.1Å; F290-F294 HydrophobicContact CE1-CG 4.33Å; F290-F294 HydrophobicContact CZ-CB 4.25Å; F290-F294 AromaticContact CZ-CD2 3.97Å; F290-F294 HydrophobicContact CZ-CD2 3.97Å; F290-F294 WeakPolarHBondContact O-CB 3.47Å; F290-F294 PolarHBondContact O-N 2.93Å
291	N	87.7	Confident	89.2	Confident	1 Å²	1	28.8 Å²	28.8	1%	0.005	14%	0.138	C	C	.	.	H	α-helix	trans	-65.4	-34.9	-176.6	-78.3	-31.5	0	0	0	112.1	E287 V288 S295 L333	E287-N291 VanDerWaalsContact O-CB 3.3Å; E287-N291 WeakPolarHBondContact O-CB 3.37Å; E287-N291 PolarHBondContact O-N 2.86Å; E287-N291 PolarHBondContact O-ND2 3.44Å; V288-N291 PolarHBondContact O-N 3.41Å; N291-S295 WeakPolarHBondContact O-CB 3.41Å; N291-S295 PolarHBondContact O-N 2.95Å; N291-S295 PolarHBondContact O-OG 3.29Å; N291-L333 HydrophobicContact CB-CD1 3.65Å; N291-L333 HydrophobicContact CB-CD2 4.47Å
292	S	92.8	Very high	89.5	Confident	0 Å²	0	27.7 Å²	27.7	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-67.6	-44.7	173.1	55.5	0	0	0	0	112	V288 L289 F290 S295 A296 W326 L333	V288-S292 VanDerWaalsContact O-CB 3.3Å; V288-S292 WeakPolarHBondContact O-CB 3.48Å; V288-S292 PolarHBondContact O-N 2.75Å; V288-S292 PolarHBondContact O-OG 2.92Å; L289-S292 WeakPolarHBondContact CA-OG 3.49Å; L289-S292 PolarHBondContact O-OG 3.32Å; F290-S292 VanDerWaalsContact C-N 3.31Å; F290-S292 PolarHBondContact O-N 3.43Å; S292-S295 PolarHBondContact O-N 3.42Å; S292-A296 WeakPolarHBondContact O-CB 3.35Å; S292-A296 PolarHBondContact O-N 3.38Å; S292-W326 PolarHBondContact OG-NE1 3.43Å; S292-L333 VanDerWaalsContact N-CD1 3.31Å
293	L	91.3	Very high	89.8	Confident	92 Å²	92	24.2 Å²	24.2	48%	0.482	12%	0.115	S	C	.	.	H	α-helix	trans	-63.4	-43.8	175.8	-77.8	170.3	0	0	0	111.8	L289 F290 S295 A296 Y297 W326	L289-L293 WeakPolarHBondContact O-CB 3.36Å; L289-L293 WeakPolarHBondContact O-CD1 3.31Å; L289-L293 VanDerWaalsContact O-CG 3.24Å; L289-L293 WeakPolarHBondContact O-CG 3.41Å; L289-L293 PolarHBondContact O-N 3.13Å; F290-L293 PolarHBondContact O-N 3.14Å; L293-S295 VanDerWaalsContact C-N 3.31Å; L293-S295 PolarHBondContact O-N 2.99Å; L293-A296 PolarHBondContact O-N 3.48Å; L293-Y297 VanDerWaalsContact O-CB 3.26Å; L293-Y297 WeakPolarHBondContact O-CB 3.25Å; L293-Y297 PolarHBondContact O-N 3.35Å; L293-W326 HydrophobicContact CD2-CD2 4.36Å; L293-W326 HydrophobicContact CD2-CG 4.34Å; L293-W326 HydrophobicContact CD2-CZ2 4.28Å
294	F	90.8	Very high	90.2	Very high	4 Å²	4	22.4 Å²	22.4	2%	0.018	11%	0.107	C	C	.	.	H	α-helix	trans	-57.5	-47.2	175.7	-176.7	-79.2	0	0	0	110.8	R131 P192 F193 F290 Y297 Y298	R131-F294 VanDerWaalsContact NH2-CE1 3.35Å; R131-F294 VanDerWaalsContact NH2-CG 3.3Å; P192-F294 HydrophobicContact CB-CD2 3.71Å; P192-F294 HydrophobicContact CB-CE2 4.04Å; P192-F294 HydrophobicContact CG-CD2 4.35Å; P192-F294 HydrophobicContact CG-CE2 4.49Å; F193-F294 HydrophobicContact CE1-CE2 4.33Å; F193-F294 AromaticContact CE2-CE2 3.87Å; F193-F294 HydrophobicContact CE2-CE2 3.87Å; F193-F294 HydrophobicContact CE2-CZ 4.36Å; F193-F294 AromaticContact CZ-CE2 3.7Å; F193-F294 HydrophobicContact CZ-CE2 3.7Å; F193-F294 HydrophobicContact CZ-CZ 4.15Å; F290-F294 HydrophobicContact CE1-CB 3.95Å; F290-F294 HydrophobicContact CE1-CD2 4.1Å; F290-F294 HydrophobicContact CE1-CG 4.33Å; F290-F294 HydrophobicContact CZ-CB 4.25Å; F290-F294 AromaticContact CZ-CD2 3.97Å; F290-F294 HydrophobicContact CZ-CD2 3.97Å; F290-F294 WeakPolarHBondContact O-CB 3.47Å; F290-F294 PolarHBondContact O-N 2.93Å; F294-Y297 WeakPolarHBondContact O-CB 3.22Å; F294-Y297 PolarHBondContact O-N 2.98Å; F294-Y298 AromaticContact CD1-CD2 3.91Å; F294-Y298 HydrophobicContact CD1-CD2 3.91Å; F294-Y298 HydrophobicContact CD1-CE2 4.38Å; F294-Y298 HydrophobicContact CD2-CD2 4.17Å; F294-Y298 AromaticContact CD2-CE2 3.94Å; F294-Y298 HydrophobicContact CD2-CE2 3.94Å; F294-Y298 AromaticContact CE1-CD2 3.37Å; F294-Y298 HydrophobicContact CE1-CD2 3.37Å; F294-Y298 AromaticContact CE1-CE2 3.65Å; F294-Y298 HydrophobicContact CE1-CE2 3.65Å; F294-Y298 AromaticContact CE1-CG 3.9Å; F294-Y298 HydrophobicContact CE1-CG 3.9Å; F294-Y298 AromaticContact CE2-CD2 3.7Å; F294-Y298 HydrophobicContact CE2-CD2 3.7Å; F294-Y298 AromaticContact CE2-CE2 3.16Å; F294-Y298 HydrophobicContact CE2-CE2 3.16Å; F294-Y298 AromaticContact CE2-CZ 3.89Å; F294-Y298 HydrophobicContact CG-CD2 4.24Å; F294-Y298 HydrophobicContact CG-CE2 4.47Å; F294-Y298 HydrophobicContact CZ-CD1 4.41Å; F294-Y298 AromaticContact CZ-CD2 3.2Å; F294-Y298 HydrophobicContact CZ-CD2 3.2Å; F294-Y298 HydrophobicContact CZ-CE1 4.13Å; F294-Y298 AromaticContact CZ-CE2 2.92Å; F294-Y298 HydrophobicContact CZ-CE2 2.92Å; F294-Y298 AromaticContact CZ-CG 3.98Å; F294-Y298 HydrophobicContact CZ-CG 3.98Å; F294-Y298 AromaticContact CZ-CZ 3.43Å; F294-Y298 VanDerWaalsContact CZ-CZ 3.43Å; F294-Y298 WeakPolarHBondContact O-CD2 3.29Å; F294-Y298 PolarHBondContact O-N 3.34Å
295	S	92.1	Very high	90.2	Very high	5 Å²	5	23.4 Å²	23.4	4%	0.035	12%	0.115	C	C	.	.	H	α-helix	trans	-62.1	-47.6	179.6	-58.8	0	0	0	0	111.3	N291 S292 L293 Y297 Y298 V299	N291-S295 WeakPolarHBondContact O-CB 3.41Å; N291-S295 PolarHBondContact O-N 2.95Å; N291-S295 PolarHBondContact O-OG 3.29Å; S292-S295 PolarHBondContact O-N 3.42Å; L293-S295 VanDerWaalsContact C-N 3.31Å; L293-S295 PolarHBondContact O-N 2.99Å; S295-Y297 VanDerWaalsContact C-N 3.34Å; S295-Y297 PolarHBondContact O-N 3.42Å; S295-Y298 PolarHBondContact O-N 3Å; S295-V299 VanDerWaalsContact O-CB 3.24Å; S295-V299 WeakPolarHBondContact O-CB 3.49Å; S295-V299 VanDerWaalsContact O-CG2 3.23Å; S295-V299 WeakPolarHBondContact O-CG2 3.3Å; S295-V299 PolarHBondContact O-N 3.47Å
296	A	94.3	Very high	90.3	Very high	2 Å²	2	22.3 Å²	22.3	2%	0.017	11%	0.109	C	C	.	.	H	α-helix	trans	-63.9	-38.4	177.5	0	0	0	0	0	112.6	S292 L293 A300 F301 L322 V325 W326	S292-A296 WeakPolarHBondContact O-CB 3.35Å; S292-A296 PolarHBondContact O-N 3.38Å; L293-A296 PolarHBondContact O-N 3.48Å; A296-A300 WeakPolarHBondContact O-CB 3.44Å; A296-A300 PolarHBondContact O-N 2.88Å; A296-F301 PolarHBondContact O-N 3.5Å; A296-L322 HydrophobicContact CB-CD1 4.02Å; A296-L322 WeakPolarHBondContact O-CD1 3.4Å; A296-V325 HydrophobicContact CB-CG1 4.39Å; A296-W326 HydrophobicContact CB-CB 3.66Å; A296-W326 HydrophobicContact CB-CG 4.32Å
297	Y	93.8	Very high	90.4	Very high	26 Å²	26	19.3 Å²	19.3	10%	0.102	10%	0.098	C	C	.	.	I	π-helix	trans	-59.1	-53.1	176.2	-177.2	-88.1	0	0	0	111.2	F188 Y191 P192 L293 F294 S295 F301 L302	F188-Y297 WeakPolarHBondContact O-CE1 3.17Å; F188-Y297 PolarHBondContact O-OH 2.87Å; Y191-Y297 AromaticContact CD1-CE2 3.94Å; Y191-Y297 HydrophobicContact CD1-CE2 3.94Å; P192-Y297 HydrophobicContact CG-CD1 3.38Å; P192-Y297 HydrophobicContact CG-CD2 4.17Å; P192-Y297 HydrophobicContact CG-CE1 3.63Å; P192-Y297 HydrophobicContact CG-CE2 4.36Å; P192-Y297 HydrophobicContact CG-CG 3.69Å; L293-Y297 VanDerWaalsContact O-CB 3.26Å; L293-Y297 WeakPolarHBondContact O-CB 3.25Å; L293-Y297 PolarHBondContact O-N 3.35Å; F294-Y297 WeakPolarHBondContact O-CB 3.22Å; F294-Y297 PolarHBondContact O-N 2.98Å; S295-Y297 VanDerWaalsContact C-N 3.34Å; S295-Y297 PolarHBondContact O-N 3.42Å; Y297-F301 HydrophobicContact CD2-CB 4.35Å; Y297-F301 AromaticContact CD2-CD1 3.68Å; Y297-F301 HydrophobicContact CD2-CD1 3.68Å; Y297-F301 HydrophobicContact CD2-CE1 4.38Å; Y297-F301 HydrophobicContact CD2-CG 4.3Å; Y297-F301 AromaticContact CE2-CD1 3.25Å; Y297-F301 HydrophobicContact CE2-CD1 3.25Å; Y297-F301 AromaticContact CE2-CE1 3.58Å; Y297-F301 HydrophobicContact CE2-CE1 3.58Å; Y297-F301 HydrophobicContact CE2-CG 4.26Å; Y297-F301 HydrophobicContact CG-CD1 4.47Å; Y297-F301 AromaticContact CZ-CD1 3.72Å; Y297-F301 AromaticContact CZ-CE1 4Å; Y297-F301 CarbonylContact O-C 3.58Å; Y297-F301 WeakPolarHBondContact O-CB 3.47Å; Y297-F301 PolarHBondContact O-N 2.95Å; Y297-F301 VanDerWaalsContact O-N 3.13Å; Y297-L302 HydrophobicContact CE1-CB 4.38Å; Y297-L302 HydrophobicContact CE1-CD1 4.17Å; Y297-L302 WeakPolarHBondContact O-CB 3.28Å; Y297-L302 PolarHBondContact O-N 3.35Å
298	Y	93.4	Very high	90.3	Very high	1 Å²	1	24.7 Å²	24.7	0%	0.004	12%	0.121	C	C	.	.	I	π-helix	trans	-71.7	-34	-177.3	-87.5	-98.6	0	0	0	113.3	F124 I125 M128 L189 P192 F193 F294 S295 L302	F124-Y298 HydrophobicContact CD1-CE1 4.43Å; F124-Y298 AromaticContact CE1-CE1 3.67Å; F124-Y298 HydrophobicContact CE1-CE1 3.67Å; F124-Y298 HydrophobicContact CZ-CE1 4.39Å; I125-Y298 HydrophobicContact CG1-CD1 4.38Å; I125-Y298 WeakPolarHBondContact CG2-O 3.45Å; M128-Y298 HydrophobicContact CB-CD1 4.01Å; M128-Y298 HydrophobicContact CB-CE1 3.89Å; M128-Y298 HydrophobicContact CG-CD1 4.37Å; M128-Y298 HydrophobicContact CG-CE1 3.77Å; L189-Y298 PolarHBondContact O-OH 2.96Å; P192-Y298 HydrophobicContact CG-CE2 3.9Å; F193-Y298 WeakPolarHBondContact CE2-OH 3.3Å; F294-Y298 AromaticContact CD1-CD2 3.91Å; F294-Y298 HydrophobicContact CD1-CD2 3.91Å; F294-Y298 HydrophobicContact CD1-CE2 4.38Å; F294-Y298 HydrophobicContact CD2-CD2 4.17Å; F294-Y298 AromaticContact CD2-CE2 3.94Å; F294-Y298 HydrophobicContact CD2-CE2 3.94Å; F294-Y298 AromaticContact CE1-CD2 3.37Å; F294-Y298 HydrophobicContact CE1-CD2 3.37Å; F294-Y298 AromaticContact CE1-CE2 3.65Å; F294-Y298 HydrophobicContact CE1-CE2 3.65Å; F294-Y298 AromaticContact CE1-CG 3.9Å; F294-Y298 HydrophobicContact CE1-CG 3.9Å; F294-Y298 AromaticContact CE2-CD2 3.7Å; F294-Y298 HydrophobicContact CE2-CD2 3.7Å; F294-Y298 AromaticContact CE2-CE2 3.16Å; F294-Y298 HydrophobicContact CE2-CE2 3.16Å; F294-Y298 AromaticContact CE2-CZ 3.89Å; F294-Y298 HydrophobicContact CG-CD2 4.24Å; F294-Y298 HydrophobicContact CG-CE2 4.47Å; F294-Y298 HydrophobicContact CZ-CD1 4.41Å; F294-Y298 AromaticContact CZ-CD2 3.2Å; F294-Y298 HydrophobicContact CZ-CD2 3.2Å; F294-Y298 HydrophobicContact CZ-CE1 4.13Å; F294-Y298 AromaticContact CZ-CE2 2.92Å; F294-Y298 HydrophobicContact CZ-CE2 2.92Å; F294-Y298 AromaticContact CZ-CG 3.98Å; F294-Y298 HydrophobicContact CZ-CG 3.98Å; F294-Y298 AromaticContact CZ-CZ 3.43Å; F294-Y298 VanDerWaalsContact CZ-CZ 3.43Å; F294-Y298 WeakPolarHBondContact O-CD2 3.29Å; F294-Y298 PolarHBondContact O-N 3.34Å; S295-Y298 PolarHBondContact O-N 3Å; Y298-L302 HydrophobicContact CD1-CD2 3.65Å; Y298-L302 HydrophobicContact CE1-CD2 3.83Å; Y298-L302 HydrophobicContact CG-CD2 4.33Å
299	V	94.8	Very high	89.5	Confident	0 Å²	0	30.8 Å²	30.8	0%	0	16%	0.164	C	C	.	.	I	π-helix	trans	-78.2	-46.3	-178.3	168.2	0	0	0	0	112.5	L83 A86 L87 L129 S295 P303 V325	L83-V299 HydrophobicContact CB-CG2 4.18Å; L83-V299 HydrophobicContact CD2-CG2 3.96Å; A86-V299 HydrophobicContact CB-CG1 3.61Å; L87-V299 HydrophobicContact CB-CG1 4.32Å; L129-V299 HydrophobicContact CD1-CG2 3.71Å; L129-V299 HydrophobicContact CD2-CG2 4.08Å; S295-V299 VanDerWaalsContact O-CB 3.24Å; S295-V299 WeakPolarHBondContact O-CB 3.49Å; S295-V299 VanDerWaalsContact O-CG2 3.23Å; S295-V299 WeakPolarHBondContact O-CG2 3.3Å; S295-V299 PolarHBondContact O-N 3.47Å; V299-P303 WeakPolarHBondContact O-CG 3.25Å; V299-V325 HydrophobicContact CB-CG1 4.33Å; V299-V325 HydrophobicContact CG1-CG1 4.08Å; V299-V325 HydrophobicContact CG1-CG2 4.47Å
300	A	92.7	Very high	88.7	Confident	0 Å²	0	33.5 Å²	33.5	0%	0	18%	0.183	C	C	.	.	I	π-helix	trans	-112.2	-39.3	-167	0	0	0	0	0	113.2	Q90 A296 L304 L322	Q90-A300 PolarHBondContact NE2-O 3.07Å; A296-A300 WeakPolarHBondContact O-CB 3.44Å; A296-A300 PolarHBondContact O-N 2.88Å; A300-L304 WeakPolarHBondContact O-CD1 3.39Å; A300-L304 WeakPolarHBondContact O-CG 3.48Å; A300-L322 HydrophobicContact CB-CB 3.88Å; A300-L322 HydrophobicContact CB-CD1 3.63Å; A300-L322 HydrophobicContact CB-CG 4.38Å
301	F	92.3	Very high	88.4	Confident	77 Å²	77	34.1 Å²	34.1	34%	0.338	19%	0.186	S	C	.	.	I	π-helix	trans	-83.3	-47.6	-177.6	-178.6	-100.1	0	0	0	112.9	A296 Y297 L304 C305 L322	A296-F301 PolarHBondContact O-N 3.5Å; Y297-F301 HydrophobicContact CD2-CB 4.35Å; Y297-F301 AromaticContact CD2-CD1 3.68Å; Y297-F301 HydrophobicContact CD2-CD1 3.68Å; Y297-F301 HydrophobicContact CD2-CE1 4.38Å; Y297-F301 HydrophobicContact CD2-CG 4.3Å; Y297-F301 AromaticContact CE2-CD1 3.25Å; Y297-F301 HydrophobicContact CE2-CD1 3.25Å; Y297-F301 AromaticContact CE2-CE1 3.58Å; Y297-F301 HydrophobicContact CE2-CE1 3.58Å; Y297-F301 HydrophobicContact CE2-CG 4.26Å; Y297-F301 HydrophobicContact CG-CD1 4.47Å; Y297-F301 AromaticContact CZ-CD1 3.72Å; Y297-F301 AromaticContact CZ-CE1 4Å; Y297-F301 CarbonylContact O-C 3.58Å; Y297-F301 WeakPolarHBondContact O-CB 3.47Å; Y297-F301 PolarHBondContact O-N 2.95Å; Y297-F301 VanDerWaalsContact O-N 3.13Å; F301-L304 WeakPolarHBondContact O-CA 3.44Å; F301-L304 VanDerWaalsContact O-CB 3.24Å; F301-L304 WeakPolarHBondContact O-CB 3.33Å; F301-L304 PolarHBondContact O-N 3.44Å; F301-C305 WeakPolarHBondContact CE1-SG 3.43Å; F301-C305 VanDerWaalsContact CZ-SG 3.59Å; F301-C305 PolarHBondContact O-N 2.94Å; F301-L322 HydrophobicContact CB-CD1 4.25Å
302	L	92.3	Very high	87.9	Confident	0 Å²	0	43.8 Å²	43.8	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-59.8	-41.7	-173.5	-170.7	62.8	0	0	0	113.3	L121 I125 F188 L189 Y297 Y298 L304 C305 F306	L121-L302 HydrophobicContact CD1-CD2 4.41Å; L121-L302 HydrophobicContact CD1-CG 4.42Å; I125-L302 HydrophobicContact CD1-CD2 4.19Å; I125-L302 HydrophobicContact CD1-CG 4.43Å; I125-L302 HydrophobicContact CG1-CD2 3.9Å; F188-L302 HydrophobicContact CB-CD1 4.18Å; L189-L302 HydrophobicContact CD1-CD1 4.17Å; Y297-L302 HydrophobicContact CE1-CB 4.38Å; Y297-L302 HydrophobicContact CE1-CD1 4.17Å; Y297-L302 WeakPolarHBondContact O-CB 3.28Å; Y297-L302 PolarHBondContact O-N 3.35Å; Y298-L302 HydrophobicContact CD1-CD2 3.65Å; Y298-L302 HydrophobicContact CE1-CD2 3.83Å; Y298-L302 HydrophobicContact CG-CD2 4.33Å; L302-L304 PolarHBondContact O-N 3.07Å; L302-C305 PolarHBondContact O-N 3.37Å; L302-F306 HydrophobicContact CD1-CD2 4.25Å; L302-F306 HydrophobicContact CD1-CE2 3.81Å; L302-F306 HydrophobicContact CG-CE2 4.43Å; L302-F306 WeakPolarHBondContact O-CD2 3.32Å
303	P	91.6	Very high	87.5	Confident	1 Å²	1	46.8 Å²	46.8	1%	0.006	24%	0.236	C	C	.	.	H	α-helix	trans	-57.4	-33.1	173.2	-26.9	37	0	0	0	113.4	L87 Q90 I94 I125 V299 F306 V307	L87-P303 HydrophobicContact CD1-CG 4.03Å; Q90-P303 HydrophobicContact CG-CB 4.23Å; Q90-P303 HydrophobicContact CG-CG 4.28Å; I94-P303 HydrophobicContact CD1-CB 3.78Å; I125-P303 HydrophobicContact CD1-CG 4Å; V299-P303 WeakPolarHBondContact O-CG 3.25Å; P303-F306 PolarHBondContact O-N 3.32Å; P303-V307 VanDerWaalsContact O-CG2 3.3Å; P303-V307 WeakPolarHBondContact O-CG2 3.47Å
304	L	89.8	Confident	87.3	Confident	27 Å²	27	44.7 Å²	44.7	14%	0.141	23%	0.225	C	C	.	.	H	α-helix	trans	-68.6	-34.6	180	-59	170.7	0	0	0	112.4	I94 A300 F301 L302 F306 V307 Y313	I94-L304 HydrophobicContact CD1-CD2 3.74Å; I94-L304 HydrophobicContact CD1-CG 4.48Å; I94-L304 HydrophobicContact CG1-CD2 3.95Å; A300-L304 WeakPolarHBondContact O-CD1 3.39Å; A300-L304 WeakPolarHBondContact O-CG 3.48Å; F301-L304 WeakPolarHBondContact O-CA 3.44Å; F301-L304 VanDerWaalsContact O-CB 3.24Å; F301-L304 WeakPolarHBondContact O-CB 3.33Å; F301-L304 PolarHBondContact O-N 3.44Å; L302-L304 PolarHBondContact O-N 3.07Å; L304-F306 PolarHBondContact O-N 2.92Å; L304-V307 PolarHBondContact O-N 3.2Å; L304-Y313 HydrophobicContact CD2-CD2 4.16Å; L304-Y313 HydrophobicContact CD2-CE2 3.58Å
305	C	87.6	Confident	87.1	Confident	30 Å²	30	50.6 Å²	50.6	20%	0.203	26%	0.255	C	S	.	.	H	α-helix	trans	-66.6	-24.2	178.3	-62.3	0	0	0	0	113.2	F188 F301 L302	F188-C305 HydrophobicContact CD2-CB 4.25Å; F301-C305 WeakPolarHBondContact CE1-SG 3.43Å; F301-C305 VanDerWaalsContact CZ-SG 3.59Å; F301-C305 PolarHBondContact O-N 2.94Å; L302-C305 PolarHBondContact O-N 3.37Å
306	F	86.8	Confident	87	Confident	13 Å²	13	59.1 Å²	59.1	6%	0.057	29%	0.286	C	S	.	.	T	Hydrogen-bonded Turn	trans	-101.9	6.6	-177.8	-75.7	-99.1	0	0	0	113.1	L121 L177 H181 N185 L189 L302 P303 L304	L121-F306 HydrophobicContact CD1-CD1 4.45Å; L121-F306 HydrophobicContact CD1-CD2 4.01Å; L121-F306 HydrophobicContact CD1-CE1 4.49Å; L121-F306 HydrophobicContact CD1-CE2 4.07Å; L121-F306 HydrophobicContact CD1-CG 4.23Å; L121-F306 HydrophobicContact CD1-CZ 4.32Å; L121-F306 HydrophobicContact CD2-CB 3.38Å; L121-F306 HydrophobicContact CD2-CD1 4.07Å; L121-F306 HydrophobicContact CD2-CD2 3.82Å; L121-F306 HydrophobicContact CD2-CG 3.48Å; L121-F306 VanDerWaalsContact CD2-CG 3.48Å; L121-F306 HydrophobicContact CG-CG 4.46Å; L177-F306 HydrophobicContact CD2-CE1 4.33Å; L177-F306 HydrophobicContact CD2-CZ 4.46Å; H181-F306 HydrophobicContact CB-CE1 4.18Å; H181-F306 AromaticContact CD2-CD1 3.91Å; H181-F306 AromaticContact CD2-CE1 3.79Å; H181-F306 AromaticContact CE1-CD1 3.72Å; H181-F306 AromaticContact CG-CD1 3.94Å; H181-F306 AromaticContact CG-CE1 3.76Å; H181-F306 AromaticContact ND1-CD1 3.83Å; H181-F306 AromaticContact NE2-CD1 3.76Å; N185-F306 HydrophobicContact CB-CE1 4Å; N185-F306 HydrophobicContact CB-CZ 3.99Å; N185-F306 WeakPolarHBondContact O-CZ 3.38Å; L189-F306 HydrophobicContact CD1-CE1 4.47Å; L189-F306 HydrophobicContact CD1-CE2 3.57Å; L189-F306 HydrophobicContact CD1-CZ 3.34Å; L302-F306 HydrophobicContact CD1-CD2 4.25Å; L302-F306 HydrophobicContact CD1-CE2 3.81Å; L302-F306 HydrophobicContact CG-CE2 4.43Å; L302-F306 WeakPolarHBondContact O-CD2 3.32Å; P303-F306 PolarHBondContact O-N 3.32Å; L304-F306 PolarHBondContact O-N 2.92Å
307	V	85.5	Confident	86.7	Confident	23 Å²	23	60 Å²	60	14%	0.139	29%	0.289	C	S	.	.	S	Bend	trans	-71.2	132.5	174.6	-180	0	0	0	0	109.9	I94 P303 L304 Q311 Y313	I94-V307 HydrophobicContact CD1-CG2 4.12Å; I94-V307 HydrophobicContact CG1-CG2 4.45Å; I94-V307 HydrophobicContact CG2-CG1 4.29Å; I94-V307 HydrophobicContact CG2-CG2 3.52Å; P303-V307 VanDerWaalsContact O-CG2 3.3Å; P303-V307 WeakPolarHBondContact O-CG2 3.47Å; L304-V307 PolarHBondContact O-N 3.2Å; V307-Q311 HydrophobicContact CG1-CB 3.77Å; V307-Q311 HydrophobicContact CG1-CG 4.12Å; V307-Y313 HydrophobicContact CB-CE1 4.39Å; V307-Y313 HydrophobicContact CG1-CD1 4.07Å; V307-Y313 HydrophobicContact CG1-CE1 4.04Å
308	K	81.5	Confident	86.5	Confident	127 Å²	127	58.8 Å²	58.8	55%	0.552	28%	0.284	S	S	*	.			trans	-63.7	140	173.4	-64.8	-177.3	-178.3	177.1	0	110	L116 T310 Q311	L116-K308 HydrophobicContact CD2-CD 4.01Å; K308-T310 PolarHBondContact O-N 3.01Å; K308-Q311 PolarHBondContact O-N 2.82Å
309	S	74	Confident	86.4	Confident	128 Å²	128	61.5 Å²	61.5	90%	0.895	30%	0.303	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.9	-17.5	-179	52.7	0	0	0	0	114.8
310	T	72.6	Confident	86.2	Confident	122 Å²	122	63 Å²	63	75%	0.748	31%	0.31	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.7	-10.4	178.9	55.4	0	0	0	0	114.1	K308	K308-T310 PolarHBondContact O-N 3.01Å
311	Q	78.6	Confident	86.2	Confident	37 Å²	37	63 Å²	63	17%	0.173	31%	0.31	C	S	.	.			trans	-91	118.6	-177.4	-176.8	67.3	13	0	0	110.8	I94 V307 K308	I94-Q311 PolarHBondContact O-NE2 3.01Å; V307-Q311 HydrophobicContact CG1-CB 3.77Å; V307-Q311 HydrophobicContact CG1-CG 4.12Å; K308-Q311 PolarHBondContact O-N 2.82Å
312	Y	78.4	Confident	86.3	Confident	205 Å²	205	61.6 Å²	61.6	80%	0.804	31%	0.306	S	S	*	.			trans	-83.7	122.1	176	-175.8	-96.5	0	0	0	111.2
313	Y	84.1	Confident	86.4	Confident	62 Å²	62	66 Å²	66	24%	0.243	33%	0.328	C	S	.	.			trans	-135.9	161.5	173.1	70.6	-88.7	0	0	0	111.2	L304 V307 M315	L304-Y313 HydrophobicContact CD2-CD2 4.16Å; L304-Y313 HydrophobicContact CD2-CE2 3.58Å; V307-Y313 HydrophobicContact CB-CE1 4.39Å; V307-Y313 HydrophobicContact CG1-CD1 4.07Å; V307-Y313 HydrophobicContact CG1-CE1 4.04Å; Y313-M315 HydrophobicContact CE2-CB 4.26Å; Y313-M315 PolarHBondContact O-N 3.24Å
314	D	86.3	Confident	86.4	Confident	48 Å²	48	66.4 Å²	66.4	26%	0.257	33%	0.33	S	S	.	.			trans	-85	98.4	-179	-165.5	-29.2	0	0	0	110	R316 W317 S318 K444 H447	D314-R316 PolarHBondContact O-N 2.79Å; D314-R316 PolarHBondContact OD1-N 2.74Å; D314-W317 HydrophobicContact CB-CB 4.04Å; D314-W317 PolarHBondContact O-N 3.21Å; D314-W317 PolarHBondContact OD1-N 3.34Å; D314-S318 PolarHBondContact O-N 3.41Å; D314-S318 VanDerWaalsContact O-N 3.11Å; D314-S318 PolarHBondContact O-OG 3.01Å; D314-K444 IonicContact OD2-NZ 3.32Å; D314-H447 IonicContact OD2-CE1 2.9Å
315	M	86.8	Confident	86.7	Confident	129 Å²	129	65.1 Å²	65.1	64%	0.635	32%	0.324	S	S	*	.	H	α-helix	trans	-60.4	-35.3	-177.4	-173.4	175.2	70.3	0	0	112.3	Y313 S318 C319	Y313-M315 HydrophobicContact CE2-CB 4.26Å; Y313-M315 PolarHBondContact O-N 3.24Å; M315-S318 PolarHBondContact O-N 2.88Å; M315-C319 WeakPolarHBondContact O-CB 3.37Å; M315-C319 PolarHBondContact O-N 3.43Å; M315-C319 PolarHBondContact O-SG 3.06Å
316	R	89.5	Confident	87.1	Confident	183 Å²	183	67.9 Å²	67.9	69%	0.691	33%	0.33	S	S	*	.	H	α-helix	trans	-63.7	-47.4	179.2	178.7	-179	176.2	148.7	4.3	110.6	D314 S318 C319 E320	D314-R316 PolarHBondContact O-N 2.79Å; D314-R316 PolarHBondContact OD1-N 2.74Å; R316-S318 VanDerWaalsContact C-N 3.34Å; R316-S318 PolarHBondContact O-N 3.21Å; R316-C319 WeakPolarHBondContact O-CB 3.38Å; R316-C319 PolarHBondContact O-N 3.4Å; R316-E320 IonicContact CZ-OE1 3.7Å; R316-E320 IonicContact NE-OE1 3.5Å; R316-E320 PolarHBondContact NE-OE1 2.84Å; R316-E320 IonicContact NH2-OE1 3.74Å; R316-E320 WeakPolarHBondContact O-CG 3.34Å; R316-E320 PolarHBondContact O-N 3.39Å
317	W	88.4	Confident	87.4	Confident	20 Å²	20	69.2 Å²	69.2	8%	0.076	34%	0.337	C	S	.	.	H	α-helix	trans	-64	-40.4	179.8	-166.5	-102.3	0	0	0	112.2	N93 D314 C319 E320 H321 S438 H447 S450 M451	N93-W317 PolarHBondContact ND2-NE1 2.89Å; D314-W317 HydrophobicContact CB-CB 4.04Å; D314-W317 PolarHBondContact O-N 3.21Å; D314-W317 PolarHBondContact OD1-N 3.34Å; W317-C319 VanDerWaalsContact C-N 3.33Å; W317-C319 PolarHBondContact O-N 3.44Å; W317-E320 PolarHBondContact O-N 3.22Å; W317-H321 WeakPolarHBondContact O-CB 3.23Å; W317-H321 PolarHBondContact O-N 3.46Å; W317-S438 WeakPolarHBondContact CH2-OG 3.25Å; W317-H447 AromaticContact CD1-CD2 3.66Å; W317-H447 AromaticContact CD1-NE2 3.86Å; W317-H447 HydrophobicContact CD2-CB 4.45Å; W317-H447 AromaticContact CD2-CD2 3.65Å; W317-H447 AromaticContact CD2-CE1 3.83Å; W317-H447 AromaticContact CD2-CG 3.78Å; W317-H447 AromaticContact CD2-ND1 3.88Å; W317-H447 AromaticContact CD2-NE2 3.8Å; W317-H447 AromaticContact CE2-CD2 3.47Å; W317-H447 VanDerWaalsContact CE2-CD2 3.47Å; W317-H447 AromaticContact CE2-CG 3.54Å; W317-H447 AromaticContact CE3-CE1 3.97Å; W317-H447 AromaticContact CE3-ND1 3.83Å; W317-H447 AromaticContact CG-CD2 3.75Å; W317-H447 AromaticContact CG-CE1 4Å; W317-H447 AromaticContact CG-NE2 3.61Å; W317-H447 HydrophobicContact CH2-CB 3.67Å; W317-H447 AromaticContact CH2-CG 3.93Å; W317-H447 VanDerWaalsContact CZ2-CA 3.47Å; W317-H447 HydrophobicContact CZ2-CB 3.38Å; W317-H447 AromaticContact CZ2-CG 3.63Å; W317-H447 HydrophobicContact CZ3-CB 4.34Å; W317-H447 AromaticContact CZ3-ND1 3.98Å; W317-H447 AromaticContact NE1-CD2 3.47Å; W317-H447 PolarHBondContact NE1-CD2 3.37Å; W317-S450 WeakPolarHBondContact CZ2-OG 3.3Å; W317-S450 PolarHBondContact NE1-OG 3.13Å; W317-M451 HydrophobicContact CH2-CE 3.21Å; W317-M451 HydrophobicContact CH2-CG 3.72Å; W317-M451 HydrophobicContact CH2-SD 4.33Å; W317-M451 HydrophobicContact CZ2-CE 3.44Å; W317-M451 VanDerWaalsContact CZ2-CE 3.44Å; W317-M451 HydrophobicContact CZ2-CG 3.65Å; W317-M451 HydrophobicContact CZ2-SD 4.34Å; W317-M451 HydrophobicContact CZ3-CE 3.83Å
318	S	89.6	Confident	87.8	Confident	1 Å²	1	68.1 Å²	68.1	1%	0.007	33%	0.33	C	S	.	.	H	α-helix	trans	-62.8	-38.1	174.3	-65.1	0	0	0	0	112.6	D314 M315 R316 H321 L322	D314-S318 PolarHBondContact O-N 3.41Å; D314-S318 VanDerWaalsContact O-N 3.11Å; D314-S318 PolarHBondContact O-OG 3.01Å; M315-S318 PolarHBondContact O-N 2.88Å; R316-S318 VanDerWaalsContact C-N 3.34Å; R316-S318 PolarHBondContact O-N 3.21Å; S318-H321 PolarHBondContact O-N 3.08Å; S318-L322 PolarHBondContact O-N 3Å
319	C	90.3	Very high	88.5	Confident	58 Å²	58	62.1 Å²	62.1	39%	0.392	30%	0.304	S	S	.	.	H	α-helix	trans	-68.3	-41.2	173.8	-72.3	0	0	0	0	112.3	M315 R316 W317 H321 L322 I323	M315-C319 WeakPolarHBondContact O-CB 3.37Å; M315-C319 PolarHBondContact O-N 3.43Å; M315-C319 PolarHBondContact O-SG 3.06Å; R316-C319 WeakPolarHBondContact O-CB 3.38Å; R316-C319 PolarHBondContact O-N 3.4Å; W317-C319 VanDerWaalsContact C-N 3.33Å; W317-C319 PolarHBondContact O-N 3.44Å; C319-H321 VanDerWaalsContact C-N 3.32Å; C319-H321 PolarHBondContact O-N 3.17Å; C319-L322 WeakPolarHBondContact O-CB 3.33Å; C319-L322 PolarHBondContact O-N 3.37Å; C319-I323 WeakPolarHBondContact O-CG1 3.48Å; C319-I323 PolarHBondContact O-N 3.45Å; C319-I323 VanDerWaalsContact O-N 3.07Å
320	E	91.8	Very high	89.4	Confident	32 Å²	32	58 Å²	58	15%	0.15	27%	0.27	C	S	.	.	H	α-helix	trans	-60.3	-44	173.8	-72.8	174.2	-176.7	0	0	110.3	R316 W317 I323 M324 Y434	R316-E320 IonicContact CZ-OE1 3.7Å; R316-E320 IonicContact NE-OE1 3.5Å; R316-E320 PolarHBondContact NE-OE1 2.84Å; R316-E320 IonicContact NH2-OE1 3.74Å; R316-E320 WeakPolarHBondContact O-CG 3.34Å; R316-E320 PolarHBondContact O-N 3.39Å; W317-E320 PolarHBondContact O-N 3.22Å; E320-I323 PolarHBondContact O-N 3.01Å; E320-M324 VanDerWaalsContact O-CG 3.3Å; E320-M324 WeakPolarHBondContact O-CG 3.49Å; E320-M324 PolarHBondContact O-N 2.87Å; E320-Y434 PolarHBondContact OE1-OH 3.49Å; E320-Y434 PolarHBondContact OE2-OH 3.35Å
321	H	92.5	Very high	90.5	Very high	1 Å²	1	52.1 Å²	52.1	1%	0.005	23%	0.234	C	C	.	.	H	α-helix	trans	-59.2	-46.6	173.7	-173.8	61.5	0	0	0	112.8	A86 Q90 W317 S318 C319 I323 M324 V325 I454	A86-H321 PolarHBondContact O-NE2 3.43Å; Q90-H321 PolarHBondContact OE1-CD2 2.97Å; W317-H321 WeakPolarHBondContact O-CB 3.23Å; W317-H321 PolarHBondContact O-N 3.46Å; S318-H321 PolarHBondContact O-N 3.08Å; C319-H321 VanDerWaalsContact C-N 3.32Å; C319-H321 PolarHBondContact O-N 3.17Å; H321-I323 VanDerWaalsContact C-N 3.34Å; H321-I323 PolarHBondContact O-N 2.89Å; H321-M324 HydrophobicContact CB-CE 4.41Å; H321-M324 PolarHBondContact O-N 3.44Å; H321-V325 VanDerWaalsContact CE1-CG2 3.47Å; H321-V325 WeakPolarHBondContact CE1-CG2 3.4Å; H321-V325 WeakPolarHBondContact O-CB 3.45Å; H321-V325 VanDerWaalsContact O-CG2 3.28Å; H321-V325 WeakPolarHBondContact O-CG2 3.24Å; H321-V325 PolarHBondContact O-N 3.48Å; H321-I454 VanDerWaalsContact CE1-CD1 3.4Å; H321-I454 WeakPolarHBondContact CE1-CD1 3.4Å; H321-I454 WeakPolarHBondContact ND1-CD1 3.27Å
322	L	94.3	Very high	91.1	Very high	47 Å²	47	51 Å²	51	25%	0.246	23%	0.229	C	C	.	.	H	α-helix	trans	-55.3	-47.7	176.5	174.7	68.3	0	0	0	112	A296 A300 F301 S318 C319 V325 W326	A296-L322 HydrophobicContact CB-CD1 4.02Å; A296-L322 WeakPolarHBondContact O-CD1 3.4Å; A300-L322 HydrophobicContact CB-CB 3.88Å; A300-L322 HydrophobicContact CB-CD1 3.63Å; A300-L322 HydrophobicContact CB-CG 4.38Å; F301-L322 HydrophobicContact CB-CD1 4.25Å; S318-L322 PolarHBondContact O-N 3Å; C319-L322 WeakPolarHBondContact O-CB 3.33Å; C319-L322 PolarHBondContact O-N 3.37Å; L322-V325 PolarHBondContact O-N 2.93Å; L322-W326 WeakPolarHBondContact O-CB 3.42Å; L322-W326 PolarHBondContact O-N 3.23Å
323	I	93.9	Very high	91.7	Very high	93 Å²	93	41.2 Å²	41.2	48%	0.477	19%	0.191	S	C	.	.	H	α-helix	trans	-66	-44.4	-179.5	-65.4	166.8	0	0	0	110.6	C319 E320 H321 W326 I327	C319-I323 WeakPolarHBondContact O-CG1 3.48Å; C319-I323 PolarHBondContact O-N 3.45Å; C319-I323 VanDerWaalsContact O-N 3.07Å; E320-I323 PolarHBondContact O-N 3.01Å; H321-I323 VanDerWaalsContact C-N 3.34Å; H321-I323 PolarHBondContact O-N 2.89Å; I323-W326 PolarHBondContact O-N 3.2Å; I323-I327 HydrophobicContact CG2-CD1 3.73Å; I323-I327 HydrophobicContact CG2-CG1 4.38Å; I323-I327 WeakPolarHBondContact O-CG1 3.3Å; I323-I327 PolarHBondContact O-N 3.33Å
324	M	92.9	Very high	92	Very high	9 Å²	9	38.4 Å²	38.4	4%	0.044	18%	0.18	C	C	.	.	H	α-helix	trans	-62	-44.5	177.8	-71.2	-175.4	-62.3	0	0	111.8	E320 H321 W326 I327 N328 Y434 Q435 M451 I454	E320-M324 VanDerWaalsContact O-CG 3.3Å; E320-M324 WeakPolarHBondContact O-CG 3.49Å; E320-M324 PolarHBondContact O-N 2.87Å; H321-M324 HydrophobicContact CB-CE 4.41Å; H321-M324 PolarHBondContact O-N 3.44Å; M324-W326 VanDerWaalsContact C-N 3.3Å; M324-W326 PolarHBondContact O-N 2.97Å; M324-I327 PolarHBondContact O-N 2.88Å; M324-N328 WeakPolarHBondContact O-CB 3.44Å; M324-N328 PolarHBondContact O-N 3.24Å; M324-Y434 HydrophobicContact SD-CD1 4.23Å; M324-Y434 HydrophobicContact SD-CE1 4.06Å; M324-Q435 HydrophobicContact SD-CG 3.74Å; M324-M451 HydrophobicContact CE-CE 3.44Å; M324-M451 VanDerWaalsContact CE-CE 3.44Å; M324-M451 HydrophobicContact CE-SD 3.94Å; M324-M451 HydrophobicContact SD-CE 3.81Å; M324-M451 HydrophobicContact SD-SD 3.96Å; M324-I454 HydrophobicContact CE-CD1 4.4Å
325	V	94.9	Very high	92	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-62.2	-42.5	178.7	171.2	0	0	0	0	110.8	Y82 A86 A296 V299 H321 L322 A329	Y82-V325 VanDerWaalsContact OH-CA 3.29Å; Y82-V325 WeakPolarHBondContact OH-CA 3.42Å; Y82-V325 PolarHBondContact OH-O 3.34Å; A86-V325 HydrophobicContact CB-CG1 4.44Å; A86-V325 HydrophobicContact CB-CG2 3.81Å; A296-V325 HydrophobicContact CB-CG1 4.39Å; V299-V325 HydrophobicContact CB-CG1 4.33Å; V299-V325 HydrophobicContact CG1-CG1 4.08Å; V299-V325 HydrophobicContact CG1-CG2 4.47Å; H321-V325 VanDerWaalsContact CE1-CG2 3.47Å; H321-V325 WeakPolarHBondContact CE1-CG2 3.4Å; H321-V325 WeakPolarHBondContact O-CB 3.45Å; H321-V325 VanDerWaalsContact O-CG2 3.28Å; H321-V325 WeakPolarHBondContact O-CG2 3.24Å; H321-V325 PolarHBondContact O-N 3.48Å; L322-V325 PolarHBondContact O-N 2.93Å; V325-A329 WeakPolarHBondContact O-CB 3.46Å; V325-A329 PolarHBondContact O-N 2.8Å
326	W	95.4	Very high	92	Very high	88 Å²	88	33.1 Å²	33.1	33%	0.333	15%	0.154	S	C	.	.	H	α-helix	trans	-62.7	-49.7	177.6	178.1	54	0	0	0	112.6	L289 S292 L293 A296 L322 I323 M324 A329 F330	L289-W326 HydrophobicContact CD2-CZ2 4.47Å; S292-W326 PolarHBondContact OG-NE1 3.43Å; L293-W326 HydrophobicContact CD2-CD2 4.36Å; L293-W326 HydrophobicContact CD2-CG 4.34Å; L293-W326 HydrophobicContact CD2-CZ2 4.28Å; A296-W326 HydrophobicContact CB-CB 3.66Å; A296-W326 HydrophobicContact CB-CG 4.32Å; L322-W326 WeakPolarHBondContact O-CB 3.42Å; L322-W326 PolarHBondContact O-N 3.23Å; I323-W326 PolarHBondContact O-N 3.2Å; M324-W326 VanDerWaalsContact C-N 3.3Å; M324-W326 PolarHBondContact O-N 2.97Å; W326-A329 PolarHBondContact O-N 3.06Å; W326-F330 VanDerWaalsContact O-CB 3.3Å; W326-F330 WeakPolarHBondContact O-CB 3.38Å; W326-F330 PolarHBondContact O-N 2.87Å
327	I	95.1	Very high	91.7	Very high	41 Å²	41	24.7 Å²	24.7	21%	0.21	12%	0.123	C	C	.	.	H	α-helix	trans	-63.5	-46.3	-178.7	-65.3	169.3	0	0	0	110.7	I323 M324 F330 V331 I427 V431	I323-I327 HydrophobicContact CG2-CD1 3.73Å; I323-I327 HydrophobicContact CG2-CG1 4.38Å; I323-I327 WeakPolarHBondContact O-CG1 3.3Å; I323-I327 PolarHBondContact O-N 3.33Å; M324-I327 PolarHBondContact O-N 2.88Å; I327-F330 WeakPolarHBondContact O-CB 3.5Å; I327-F330 PolarHBondContact O-N 3.32Å; I327-V331 HydrophobicContact CG2-CG2 4.5Å; I327-V331 WeakPolarHBondContact O-CG2 3.44Å; I327-V331 PolarHBondContact O-N 2.94Å; I327-I427 HydrophobicContact CG2-CG2 3.42Å; I327-I427 VanDerWaalsContact CG2-CG2 3.42Å; I327-V431 HydrophobicContact CB-CG2 4.2Å; I327-V431 HydrophobicContact CD1-CG2 4.28Å; I327-V431 HydrophobicContact CG2-CG2 3.59Å
328	N	93.9	Very high	91.4	Very high	0 Å²	0	24.3 Å²	24.3	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-68	-39.5	180	-178.7	37	0	0	0	111.8	Y82 M324 F330 V331 M332 N458	Y82-N328 WeakPolarHBondContact CE2-ND2 3.35Å; Y82-N328 WeakPolarHBondContact OH-CB 3.19Å; Y82-N328 PolarHBondContact OH-ND2 3.48Å; M324-N328 WeakPolarHBondContact O-CB 3.44Å; M324-N328 PolarHBondContact O-N 3.24Å; N328-F330 VanDerWaalsContact C-N 3.29Å; N328-F330 PolarHBondContact O-N 2.93Å; N328-V331 PolarHBondContact O-N 3.1Å; N328-M332 WeakPolarHBondContact O-CG 3.28Å; N328-M332 PolarHBondContact O-N 2.72Å; N328-N458 PolarHBondContact ND2-OD1 3Å
329	A	94.4	Very high	91	Very high	0 Å²	0	25.3 Å²	25.3	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-60.5	-40.4	172.6	0	0	0	0	0	111.8	F79 Y82 V325 W326 L333	F79-A329 HydrophobicContact CE2-CB 4.01Å; F79-A329 HydrophobicContact CZ-CB 4.28Å; Y82-A329 HydrophobicContact CE1-CB 4.4Å; V325-A329 WeakPolarHBondContact O-CB 3.46Å; V325-A329 PolarHBondContact O-N 2.8Å; W326-A329 PolarHBondContact O-N 3.06Å; A329-L333 VanDerWaalsContact O-CB 3.3Å; A329-L333 WeakPolarHBondContact O-CB 3.41Å; A329-L333 WeakPolarHBondContact O-CD1 3.25Å; A329-L333 WeakPolarHBondContact O-CG 3.48Å; A329-L333 PolarHBondContact O-N 3.44Å
330	F	94.6	Very high	90.5	Very high	41 Å²	41	23.7 Å²	23.7	18%	0.18	12%	0.118	C	C	.	.	H	α-helix	trans	-60.6	-46.6	174.5	173.3	-92.9	0	0	0	111.8	V288 L289 W326 I327 N328 T334	V288-F330 HydrophobicContact CG1-CD2 3.54Å; V288-F330 HydrophobicContact CG1-CE2 3.66Å; V288-F330 HydrophobicContact CG1-CG 4.32Å; L289-F330 HydrophobicContact CD2-CD2 3.91Å; L289-F330 HydrophobicContact CD2-CE2 3.64Å; L289-F330 HydrophobicContact CG-CE2 4.12Å; W326-F330 VanDerWaalsContact O-CB 3.3Å; W326-F330 WeakPolarHBondContact O-CB 3.38Å; W326-F330 PolarHBondContact O-N 2.87Å; I327-F330 WeakPolarHBondContact O-CB 3.5Å; I327-F330 PolarHBondContact O-N 3.32Å; N328-F330 VanDerWaalsContact C-N 3.29Å; N328-F330 PolarHBondContact O-N 2.93Å; F330-T334 VanDerWaalsContact O-CB 3.32Å; F330-T334 WeakPolarHBondContact O-CB 3.24Å; F330-T334 PolarHBondContact O-N 3.02Å; F330-T334 PolarHBondContact O-OG1 2.85Å
331	V	93.9	Very high	90	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-62.5	-50.9	177.5	173.3	0	0	0	0	110.6	I327 N328 L333 T334 T335 I427 E428 V461 L465	I327-V331 HydrophobicContact CG2-CG2 4.5Å; I327-V331 WeakPolarHBondContact O-CG2 3.44Å; I327-V331 PolarHBondContact O-N 2.94Å; N328-V331 PolarHBondContact O-N 3.1Å; V331-L333 PolarHBondContact O-N 3.35Å; V331-T334 PolarHBondContact O-N 3.39Å; V331-T335 WeakPolarHBondContact O-CG2 3.3Å; V331-T335 PolarHBondContact O-N 3.37Å; V331-I427 HydrophobicContact CG2-CG2 4Å; V331-E428 HydrophobicContact CG1-CB 4.38Å; V331-V461 HydrophobicContact CG1-CG1 3.79Å; V331-L465 HydrophobicContact CG1-CD1 3.81Å
332	M	91.6	Very high	89.6	Confident	12 Å²	12	26.8 Å²	26.8	6%	0.059	13%	0.131	C	C	.	.	H	α-helix	trans	-55.8	-49.7	178.7	-71.1	-176.8	76.6	0	0	111.7	F75 F79 Y82 N328 T334 T335 Q336 V461	F75-M332 HydrophobicContact CE2-CB 4.32Å; F75-M332 VanDerWaalsContact CE2-O 3.27Å; F75-M332 WeakPolarHBondContact CE2-O 3.48Å; F75-M332 HydrophobicContact CZ-CB 4.19Å; F75-M332 VanDerWaalsContact CZ-O 3.29Å; F75-M332 WeakPolarHBondContact CZ-O 3.3Å; F79-M332 HydrophobicContact CB-CE 4.18Å; F79-M332 HydrophobicContact CD2-CB 4.14Å; F79-M332 HydrophobicContact CD2-CE 3.92Å; F79-M332 HydrophobicContact CD2-SD 3.94Å; F79-M332 HydrophobicContact CE2-CB 4.38Å; Y82-M332 HydrophobicContact CD1-SD 3.79Å; Y82-M332 HydrophobicContact CE1-SD 4.27Å; Y82-M332 HydrophobicContact CG-SD 4.01Å; N328-M332 WeakPolarHBondContact O-CG 3.28Å; N328-M332 PolarHBondContact O-N 2.72Å; M332-T334 PolarHBondContact O-N 3.36Å; M332-T335 PolarHBondContact O-N 3.36Å; M332-T335 PolarHBondContact O-OG1 3.21Å; M332-Q336 PolarHBondContact O-N 2.95Å; M332-V461 HydrophobicContact CE-CG2 4.46Å; M332-V461 HydrophobicContact CG-CG1 4.33Å; M332-V461 HydrophobicContact CG-CG2 3.66Å; M332-V461 HydrophobicContact SD-CG2 4.06Å
333	L	90.9	Very high	89	Confident	0 Å²	0	25.4 Å²	25.4	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-64.6	-40.3	178.6	-71.7	168.2	0	0	0	112.4	F79 R132 V288 N291 S292 A329 V331 T335 Q336 L337	F79-L333 HydrophobicContact CE1-CD2 4.38Å; F79-L333 HydrophobicContact CE2-CG 4.21Å; F79-L333 HydrophobicContact CZ-CD1 4.1Å; F79-L333 HydrophobicContact CZ-CD2 4.21Å; F79-L333 HydrophobicContact CZ-CG 4.09Å; R132-L333 VanDerWaalsContact CZ-CD2 3.47Å; R132-L333 VanDerWaalsContact NH1-CD2 3.29Å; V288-L333 HydrophobicContact CG1-CB 3.99Å; V288-L333 HydrophobicContact CG2-CB 4.3Å; N291-L333 HydrophobicContact CB-CD1 3.65Å; N291-L333 HydrophobicContact CB-CD2 4.47Å; S292-L333 VanDerWaalsContact N-CD1 3.31Å; A329-L333 VanDerWaalsContact O-CB 3.3Å; A329-L333 WeakPolarHBondContact O-CB 3.41Å; A329-L333 WeakPolarHBondContact O-CD1 3.25Å; A329-L333 WeakPolarHBondContact O-CG 3.48Å; A329-L333 PolarHBondContact O-N 3.44Å; V331-L333 PolarHBondContact O-N 3.35Å; L333-T335 VanDerWaalsContact C-N 3.29Å; L333-T335 PolarHBondContact O-N 3.48Å; L333-Q336 PolarHBondContact O-N 3.17Å; L333-Q336 VanDerWaalsContact O-N 3.14Å; L333-L337 HydrophobicContact CD2-CD1 4.45Å; L333-L337 VanDerWaalsContact O-CD1 3.27Å; L333-L337 WeakPolarHBondContact O-CD1 3.23Å; L333-L337 PolarHBondContact O-N 3.21Å
334	T	90.3	Very high	88.5	Confident	3 Å²	3	21.6 Å²	21.6	2%	0.018	11%	0.106	C	C	.	.	H	α-helix	trans	-60.4	-40.9	176.5	-54.5	0	0	0	0	111	V288 F330 V331 M332 Q336 L338 L424	V288-T334 WeakPolarHBondContact CG1-OG1 3.36Å; F330-T334 VanDerWaalsContact O-CB 3.32Å; F330-T334 WeakPolarHBondContact O-CB 3.24Å; F330-T334 PolarHBondContact O-N 3.02Å; F330-T334 PolarHBondContact O-OG1 2.85Å; V331-T334 PolarHBondContact O-N 3.39Å; M332-T334 PolarHBondContact O-N 3.36Å; T334-Q336 VanDerWaalsContact C-N 3.26Å; T334-Q336 PolarHBondContact O-N 3.39Å; T334-L338 HydrophobicContact CG2-CD1 4.13Å; T334-L338 WeakPolarHBondContact O-CB 3.49Å; T334-L338 PolarHBondContact O-N 3.48Å; T334-L424 HydrophobicContact CG2-CD1 4.1Å; T334-L424 HydrophobicContact CG2-CD2 3.79Å; T334-L424 HydrophobicContact CG2-CG 4.37Å
335	T	87.6	Confident	88.1	Confident	27 Å²	27	21.6 Å²	21.6	17%	0.166	11%	0.106	C	C	.	.	H	α-helix	trans	-66.1	-26.6	178	63.9	0	0	0	0	113.9	V331 M332 L333 L424 L465	V331-T335 WeakPolarHBondContact O-CG2 3.3Å; V331-T335 PolarHBondContact O-N 3.37Å; M332-T335 PolarHBondContact O-N 3.36Å; M332-T335 PolarHBondContact O-OG1 3.21Å; L333-T335 VanDerWaalsContact C-N 3.29Å; L333-T335 PolarHBondContact O-N 3.48Å; T335-L424 HydrophobicContact CG2-CD2 3.85Å; T335-L465 HydrophobicContact CG2-CD2 3.46Å; T335-L465 VanDerWaalsContact CG2-CD2 3.46Å; T335-L465 HydrophobicContact CG2-CG 4.35Å
336	Q	85.6	Confident	87.7	Confident	40 Å²	40	21.6 Å²	21.6	19%	0.187	11%	0.106	C	C	.	.	H	α-helix	trans	-83.3	-47.9	177.4	-174.6	-164.4	20.9	0	0	111.7	F75 E76 M332 L333 T334	F75-Q336 HydrophobicContact CD1-CB 4.11Å; F75-Q336 HydrophobicContact CD1-CG 3.76Å; F75-Q336 VanDerWaalsContact CD1-OE1 3.23Å; F75-Q336 HydrophobicContact CD2-CB 4.09Å; F75-Q336 HydrophobicContact CD2-CG 4.35Å; F75-Q336 HydrophobicContact CE1-CB 3.84Å; F75-Q336 HydrophobicContact CE1-CG 3.9Å; F75-Q336 HydrophobicContact CE2-CB 3.78Å; F75-Q336 HydrophobicContact CE2-CG 4.44Å; F75-Q336 HydrophobicContact CG-CB 4.24Å; F75-Q336 HydrophobicContact CG-CG 4.01Å; F75-Q336 HydrophobicContact CZ-CB 3.64Å; F75-Q336 HydrophobicContact CZ-CG 4.22Å; E76-Q336 PolarHBondContact OE1-NE2 3.34Å; E76-Q336 PolarHBondContact OE1-OE1 3.49Å; M332-Q336 PolarHBondContact O-N 2.95Å; L333-Q336 PolarHBondContact O-N 3.17Å; L333-Q336 VanDerWaalsContact O-N 3.14Å; T334-Q336 VanDerWaalsContact C-N 3.26Å; T334-Q336 PolarHBondContact O-N 3.39Å
337	L	83.2	Confident	87.2	Confident	6 Å²	6	19.1 Å²	19.1	3%	0.031	10%	0.098	C	C	.	.	H	α-helix	trans	-79	-22.9	-174.9	-81.9	79.3	0	0	0	112.9	R284 E287 V288 L333 P339	R284-L337 PolarHBondContact NH1-O 2.95Å; E287-L337 HydrophobicContact CB-CD2 3.98Å; E287-L337 VanDerWaalsContact CD-CD2 3.41Å; E287-L337 HydrophobicContact CG-CD2 3.89Å; E287-L337 WeakPolarHBondContact OE2-CD2 3.37Å; V288-L337 HydrophobicContact CG2-CB 3.86Å; V288-L337 HydrophobicContact CG2-CD1 4.32Å; V288-L337 HydrophobicContact CG2-CD2 3.79Å; V288-L337 HydrophobicContact CG2-CG 4.2Å; L333-L337 HydrophobicContact CD2-CD1 4.45Å; L333-L337 VanDerWaalsContact O-CD1 3.27Å; L333-L337 WeakPolarHBondContact O-CD1 3.23Å; L333-L337 PolarHBondContact O-N 3.21Å; L337-P339 VanDerWaalsContact O-CD 3.3Å; L337-P339 WeakPolarHBondContact O-CD 3.48Å
338	L	83.3	Confident	86.7	Confident	11 Å²	11	19.2 Å²	19.2	6%	0.058	10%	0.097	C	C	.	.	S	Bend	trans	-118.4	69.4	175	-67.9	83.5	0	0	0	110.5	F281 R284 I285 V288 T334 Y342 L420	F281-L338 HydrophobicContact CD2-CD2 3.7Å; F281-L338 HydrophobicContact CE2-CD2 3.3Å; F281-L338 HydrophobicContact CZ-CD2 4.33Å; R284-L338 HydrophobicContact CB-CD1 4.26Å; I285-L338 HydrophobicContact CD1-CD1 4Å; I285-L338 HydrophobicContact CD1-CD2 4.02Å; V288-L338 HydrophobicContact CG2-CD1 4.38Å; T334-L338 HydrophobicContact CG2-CD1 4.13Å; T334-L338 WeakPolarHBondContact O-CB 3.49Å; T334-L338 PolarHBondContact O-N 3.48Å; L338-Y342 HydrophobicContact CB-CD1 4.47Å; L338-Y342 HydrophobicContact CG-CD1 4.35Å; L338-Y342 HydrophobicContact CG-CE1 4.43Å; L338-L420 HydrophobicContact CD2-CD2 3.74Å
339	P	81.6	Confident	86.3	Confident	23 Å²	23	19.2 Å²	19.2	15%	0.149	10%	0.097	C	C	.	.			trans	-63.2	158	178.5	25.7	-31.8	0	0	0	111.3	I258 L337 K341 Y342 C343	I258-P339 HydrophobicContact CD1-CG 4.04Å; L337-P339 VanDerWaalsContact O-CD 3.3Å; L337-P339 WeakPolarHBondContact O-CD 3.48Å; P339-K341 PolarHBondContact O-N 2.91Å; P339-K341 VanDerWaalsContact O-N 3.15Å; P339-Y342 WeakPolarHBondContact O-CA 3.26Å; P339-Y342 WeakPolarHBondContact O-CB 3.32Å; P339-Y342 PolarHBondContact O-N 3.35Å; P339-C343 PolarHBondContact O-N 3.22Å
340	S	79.6	Confident	85.9	Confident	24 Å²	24	19.2 Å²	19.2	17%	0.168	10%	0.097	C	C	.	.	H	α-helix	trans	-54.1	-36.5	-179.3	53.8	0	0	0	0	113.4	L67 Y342 C343 D344	L67-S340 WeakPolarHBondContact CD1-OG 3.35Å; S340-Y342 VanDerWaalsContact C-N 3.35Å; S340-Y342 PolarHBondContact O-N 3.47Å; S340-C343 PolarHBondContact O-N 3.1Å; S340-D344 PolarHBondContact O-N 3.43Å
341	K	80.3	Confident	85.4	Confident	97 Å²	97	18.1 Å²	18.1	42%	0.422	10%	0.095	S	C	.	.	H	α-helix	trans	-61.5	-39.4	174.5	-65.6	-173.2	175.3	-169.7	0	113.1	D66 P339 D344 L345	D66-K341 WeakPolarHBondContact OD1-CE 3.48Å; D66-K341 IonicContact OD1-NZ 2.67Å; D66-K341 PolarHBondContact OD1-NZ 3.45Å; P339-K341 PolarHBondContact O-N 2.91Å; P339-K341 VanDerWaalsContact O-N 3.15Å; K341-D344 PolarHBondContact O-N 2.95Å; K341-L345 PolarHBondContact O-N 3.43Å
342	Y	83.6	Confident	84.9	Confident	0 Å²	0	18.8 Å²	18.8	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-71.5	-38.2	176.7	-179.1	-106.3	0	0	0	111.4	I258 D280 F281 L338 P339 S340 D344 L345 L346	I258-Y342 HydrophobicContact CG2-CD2 4.29Å; D280-Y342 WeakPolarHBondContact OD2-CE2 3.24Å; D280-Y342 VanDerWaalsContact OD2-CZ 3.24Å; D280-Y342 PolarHBondContact OD2-OH 2.79Å; F281-Y342 WeakPolarHBondContact CA-OH 3.37Å; F281-Y342 HydrophobicContact CD2-CE1 4.35Å; F281-Y342 PolarHBondContact N-OH 2.83Å; F281-Y342 VanDerWaalsContact N-OH 3.15Å; L338-Y342 HydrophobicContact CB-CD1 4.47Å; L338-Y342 HydrophobicContact CG-CD1 4.35Å; L338-Y342 HydrophobicContact CG-CE1 4.43Å; P339-Y342 WeakPolarHBondContact O-CA 3.26Å; P339-Y342 WeakPolarHBondContact O-CB 3.32Å; P339-Y342 PolarHBondContact O-N 3.35Å; S340-Y342 VanDerWaalsContact C-N 3.35Å; S340-Y342 PolarHBondContact O-N 3.47Å; Y342-D344 VanDerWaalsContact C-N 3.28Å; Y342-D344 PolarHBondContact O-N 3.38Å; Y342-L345 HydrophobicContact CD2-CD2 4.04Å; Y342-L345 HydrophobicContact CE2-CD2 4.28Å; Y342-L345 WeakPolarHBondContact O-CB 3.49Å; Y342-L345 PolarHBondContact O-N 3.23Å; Y342-L346 HydrophobicContact CD1-CD1 3.82Å; Y342-L346 HydrophobicContact CD1-CG 4.45Å; Y342-L346 HydrophobicContact CE1-CD1 3.45Å; Y342-L346 VanDerWaalsContact CE1-CD1 3.45Å; Y342-L346 HydrophobicContact CE1-CG 4.15Å; Y342-L346 WeakPolarHBondContact O-CG 3.49Å; Y342-L346 PolarHBondContact O-N 2.98Å
343	C	83.4	Confident	84.5	Confident	19 Å²	19	18.2 Å²	18.2	13%	0.128	10%	0.096	C	C	.	.	H	α-helix	trans	-63.2	-35.8	173	-65.1	0	0	0	0	112.1	P339 S340 H347	P339-C343 PolarHBondContact O-N 3.22Å; S340-C343 PolarHBondContact O-N 3.1Å; C343-H347 WeakPolarHBondContact O-CB 3.37Å; C343-H347 PolarHBondContact O-N 3.05Å
344	D	82.9	Confident	84.2	Confident	13 Å²	13	18.2 Å²	18.2	7%	0.07	10%	0.096	C	C	.	.	H	α-helix	trans	-67.6	-42.5	173.4	-175.7	48.7	0	0	0	112.1	I64 S340 K341 Y342 L346 H347 K348 Y476	I64-D344 HydrophobicContact CD1-CB 3.61Å; I64-D344 WeakPolarHBondContact CD1-OD1 3.19Å; S340-D344 PolarHBondContact O-N 3.43Å; K341-D344 PolarHBondContact O-N 2.95Å; Y342-D344 VanDerWaalsContact C-N 3.28Å; Y342-D344 PolarHBondContact O-N 3.38Å; D344-L346 PolarHBondContact O-N 2.88Å; D344-H347 WeakPolarHBondContact O-CB 3.48Å; D344-H347 PolarHBondContact O-N 3.38Å; D344-H347 VanDerWaalsContact O-N 3.15Å; D344-K348 VanDerWaalsContact O-CG 3.31Å; D344-K348 WeakPolarHBondContact O-CG 3.5Å; D344-K348 PolarHBondContact O-N 3.35Å; D344-K348 WeakPolarHBondContact OD2-CE 3.49Å; D344-K348 IonicContact OD2-NZ 2.67Å; D344-K348 PolarHBondContact OD2-NZ 2.97Å; D344-Y476 PolarHBondContact OD1-OH 3.16Å
345	L	84.1	Confident	83.9	Confident	9 Å²	9	21.7 Å²	21.7	5%	0.047	11%	0.11	C	C	.	.	H	α-helix	trans	-53.3	-52	171.3	170	67.5	0	0	0	111.3	I258 P259 H261 L277 K341 Y342 H347 K348 S349	I258-L345 HydrophobicContact CG2-CD2 4.09Å; P259-L345 HydrophobicContact CB-CD2 4.28Å; P259-L345 WeakPolarHBondContact O-CD2 3.49Å; H261-L345 HydrophobicContact CB-CD1 3.44Å; H261-L345 VanDerWaalsContact CB-CD1 3.44Å; L277-L345 HydrophobicContact CD1-CG 4.33Å; L277-L345 HydrophobicContact CD2-CD2 3.66Å; L277-L345 HydrophobicContact CD2-CG 4.05Å; K341-L345 PolarHBondContact O-N 3.43Å; Y342-L345 HydrophobicContact CD2-CD2 4.04Å; Y342-L345 HydrophobicContact CE2-CD2 4.28Å; Y342-L345 WeakPolarHBondContact O-CB 3.49Å; Y342-L345 PolarHBondContact O-N 3.23Å; L345-H347 VanDerWaalsContact C-N 3.27Å; L345-H347 PolarHBondContact O-N 3.42Å; L345-K348 PolarHBondContact O-N 3.41Å; L345-S349 PolarHBondContact O-N 2.92Å; L345-S349 PolarHBondContact O-OG 3.05Å
346	L	85.8	Confident	83.8	Confident	0 Å²	0	21.4 Å²	21.4	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-60.9	-37.6	177.9	-69	171.2	0	0	0	112.3	L277 F281 Y342 D344 A350 F410 F414	L277-L346 HydrophobicContact CB-CD2 3.83Å; L277-L346 HydrophobicContact CD1-CD2 4.36Å; L277-L346 HydrophobicContact CD2-CD2 4.37Å; L277-L346 HydrophobicContact CG-CD2 4.42Å; F281-L346 HydrophobicContact CD2-CD1 3.92Å; Y342-L346 HydrophobicContact CD1-CD1 3.82Å; Y342-L346 HydrophobicContact CD1-CG 4.45Å; Y342-L346 HydrophobicContact CE1-CD1 3.45Å; Y342-L346 VanDerWaalsContact CE1-CD1 3.45Å; Y342-L346 HydrophobicContact CE1-CG 4.15Å; Y342-L346 WeakPolarHBondContact O-CG 3.49Å; Y342-L346 PolarHBondContact O-N 2.98Å; D344-L346 PolarHBondContact O-N 2.88Å; L346-A350 WeakPolarHBondContact O-CB 3.44Å; L346-A350 PolarHBondContact O-N 3.16Å; L346-F410 HydrophobicContact CD2-CE2 3.85Å; L346-F410 HydrophobicContact CD2-CZ 3.81Å; L346-F414 HydrophobicContact CB-CB 4.25Å; L346-F414 HydrophobicContact CB-CD1 3.8Å; L346-F414 HydrophobicContact CB-CD2 4.36Å; L346-F414 HydrophobicContact CB-CE1 4.25Å; L346-F414 HydrophobicContact CB-CG 3.87Å; L346-F414 HydrophobicContact CD1-CD1 3.93Å; L346-F414 HydrophobicContact CD1-CE1 3.51Å; L346-F414 HydrophobicContact CD1-CE2 4.44Å; L346-F414 HydrophobicContact CD1-CZ 3.79Å; L346-F414 HydrophobicContact CG-CD1 4.46Å; L346-F414 HydrophobicContact CG-CE1 4.43Å
347	H	86.8	Confident	83.7	Confident	36 Å²	36	24 Å²	24	17%	0.167	12%	0.118	C	C	.	.	H	α-helix	trans	-65.2	-43.6	176	177.3	58	0	0	0	112.2	C343 D344 L345 A350 A351 F414 H415 P417	C343-H347 WeakPolarHBondContact O-CB 3.37Å; C343-H347 PolarHBondContact O-N 3.05Å; D344-H347 WeakPolarHBondContact O-CB 3.48Å; D344-H347 PolarHBondContact O-N 3.38Å; D344-H347 VanDerWaalsContact O-N 3.15Å; L345-H347 VanDerWaalsContact C-N 3.27Å; L345-H347 PolarHBondContact O-N 3.42Å; H347-A350 PolarHBondContact O-N 3.3Å; H347-A351 WeakPolarHBondContact O-CB 3.27Å; H347-A351 PolarHBondContact O-N 3Å; H347-F414 PolarHBondContact ND1-O 3.49Å; H347-H415 PolarHBondContact CE1-O 2.95Å; H347-H415 PolarHBondContact ND1-O 3.17Å; H347-P417 HydrophobicContact CB-CB 4.11Å
348	K	84.6	Confident	83.7	Confident	43 Å²	43	29.8 Å²	29.8	19%	0.187	14%	0.143	C	C	.	.	H	α-helix	trans	-61.7	-49	177.1	-68.8	177.7	-175.2	157.5	0	111.3	H61 D344 L345 A350 A351 H352	H61-K348 HydrophobicContact CB-CD 4.4Å; H61-K348 WeakPolarHBondContact ND1-CG 3.22Å; D344-K348 VanDerWaalsContact O-CG 3.31Å; D344-K348 WeakPolarHBondContact O-CG 3.5Å; D344-K348 PolarHBondContact O-N 3.35Å; D344-K348 WeakPolarHBondContact OD2-CE 3.49Å; D344-K348 IonicContact OD2-NZ 2.67Å; D344-K348 PolarHBondContact OD2-NZ 2.97Å; L345-K348 PolarHBondContact O-N 3.41Å; K348-A350 VanDerWaalsContact C-N 3.31Å; K348-A350 PolarHBondContact O-N 3.35Å; K348-A351 WeakPolarHBondContact O-CB 3.39Å; K348-A351 PolarHBondContact O-N 3.11Å; K348-A351 VanDerWaalsContact O-N 3.13Å; K348-H352 PolarHBondContact O-CD2 3.44Å; K348-H352 PolarHBondContact O-N 3.48Å; K348-H352 VanDerWaalsContact O-N 3.15Å
349	S	84.6	Confident	83.6	Confident	0 Å²	0	30.5 Å²	30.5	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-64.8	-36.4	177.6	-48.2	0	0	0	0	111.6	H261 E273 L277 L345 A351 H352 L353	H261-S349 PolarHBondContact CD2-OG 3.33Å; E273-S349 PolarHBondContact OE1-OG 3.3Å; L277-S349 WeakPolarHBondContact CD1-OG 3.41Å; L345-S349 PolarHBondContact O-N 2.92Å; L345-S349 PolarHBondContact O-OG 3.05Å; S349-A351 VanDerWaalsContact C-N 3.34Å; S349-A351 PolarHBondContact O-N 2.91Å; S349-H352 PolarHBondContact O-N 3.15Å; S349-L353 WeakPolarHBondContact O-CB 3.35Å; S349-L353 PolarHBondContact O-N 3.31Å
350	A	86.4	Confident	83.3	Confident	0 Å²	0	37.5 Å²	37.5	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-66	-33.9	173.5	0	0	0	0	0	113.1	L346 H347 K348 L353 G354 F410 Y411 F414	L346-A350 WeakPolarHBondContact O-CB 3.44Å; L346-A350 PolarHBondContact O-N 3.16Å; H347-A350 PolarHBondContact O-N 3.3Å; K348-A350 VanDerWaalsContact C-N 3.31Å; K348-A350 PolarHBondContact O-N 3.35Å; A350-L353 PolarHBondContact O-N 3.46Å; A350-G354 PolarHBondContact O-N 2.77Å; A350-F410 HydrophobicContact CB-CD1 4.18Å; A350-F410 HydrophobicContact CB-CE1 3.86Å; A350-Y411 VanDerWaalsContact O-CD2 3.22Å; A350-Y411 WeakPolarHBondContact O-CD2 3.38Å; A350-Y411 WeakPolarHBondContact O-CE2 3.48Å; A350-F414 HydrophobicContact CB-CB 3.85Å
351	A	83.9	Confident	82.3	Confident	17 Å²	17	43.8 Å²	43.8	14%	0.14	20%	0.204	C	C	.	.	H	α-helix	trans	-67.4	-35.9	175.4	0	0	0	0	0	112.3	V59 H347 K348 S349	V59-A351 HydrophobicContact CG1-CB 4.09Å; H347-A351 WeakPolarHBondContact O-CB 3.27Å; H347-A351 PolarHBondContact O-N 3Å; K348-A351 WeakPolarHBondContact O-CB 3.39Å; K348-A351 PolarHBondContact O-N 3.11Å; K348-A351 VanDerWaalsContact O-N 3.13Å; S349-A351 VanDerWaalsContact C-N 3.34Å; S349-A351 PolarHBondContact O-N 2.91Å
352	H	82.6	Confident	81.4	Confident	15 Å²	15	42.4 Å²	42.4	7%	0.069	22%	0.217	C	C	.	.	H	α-helix	trans	-71.8	-35.2	173.3	-71.6	-64.3	0	0	0	112.9	V59 H61 H261 I270 K348 S349 Y397	V59-H352 VanDerWaalsContact CB-CE1 3.44Å; V59-H352 WeakPolarHBondContact CB-CE1 3.36Å; V59-H352 VanDerWaalsContact CG2-ND1 3.32Å; V59-H352 WeakPolarHBondContact CG2-ND1 3.32Å; H61-H352 AromaticContact CE1-CD2 3.96Å; H61-H352 AromaticContact CE1-NE2 3.22Å; H61-H352 PolarHBondContact CE1-NE2 3.43Å; H61-H352 AromaticContact NE2-CE1 3.88Å; H61-H352 AromaticContact NE2-NE2 3.14Å; H61-H352 PolarHBondContact NE2-NE2 3.48Å; H61-H352 VanDerWaalsContact NE2-NE2 3.14Å; H261-H352 AromaticContact CE1-CD2 3.67Å; H261-H352 AromaticContact CE1-NE2 3.54Å; H261-H352 AromaticContact NE2-CD2 3.56Å; H261-H352 AromaticContact NE2-NE2 3.92Å; I270-H352 HydrophobicContact CD1-CB 4.37Å; I270-H352 HydrophobicContact CG2-CB 3.96Å; K348-H352 PolarHBondContact O-CD2 3.44Å; K348-H352 PolarHBondContact O-N 3.48Å; K348-H352 VanDerWaalsContact O-N 3.15Å; S349-H352 PolarHBondContact O-N 3.15Å; H352-Y397 WeakPolarHBondContact O-CB 3.34Å
353	L	83.8	Confident	80.1	Confident	0 Å²	0	46.1 Å²	46.1	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-68.3	-45.1	-179	-175.8	67.2	0	0	0	113.2	V274 S349 A350 N398 V399 A400 H407 F410	V274-L353 HydrophobicContact CG1-CD1 4.48Å; V274-L353 HydrophobicContact CG1-CD2 3.84Å; V274-L353 HydrophobicContact CG2-CB 4.18Å; V274-L353 HydrophobicContact CG2-CD1 4.2Å; V274-L353 HydrophobicContact CG2-CD2 4.2Å; V274-L353 HydrophobicContact CG2-CG 4.42Å; S349-L353 WeakPolarHBondContact O-CB 3.35Å; S349-L353 PolarHBondContact O-N 3.31Å; A350-L353 PolarHBondContact O-N 3.46Å; L353-N398 PolarHBondContact O-OD1 2.88Å; L353-V399 PolarHBondContact O-N 3.48Å; L353-A400 HydrophobicContact CD1-CB 4Å; L353-A400 HydrophobicContact CG-CB 4.05Å; L353-A400 PolarHBondContact O-N 3.07Å; L353-H407 HydrophobicContact CD2-CB 4.12Å; L353-F410 HydrophobicContact CD2-CD1 3.91Å
354	G	83.9	Confident	78.9	Confident	0 Å²	0	52.1 Å²	52.1	0%	0	26%	0.264	C	S	.	.			trans	73.1	-173.8	-174.8	0	0	0	0	0	114.6	A350 Y397 Y411	A350-G354 PolarHBondContact O-N 2.77Å; G354-Y397 WeakPolarHBondContact CA-O 3.19Å; G354-Y411 VanDerWaalsContact C-CE2 3.49Å; G354-Y411 VanDerWaalsContact CA-CE2 3.46Å; G354-Y411 WeakPolarHBondContact O-CD2 3.21Å
355	K	85.3	Confident	77.6	Confident	75 Å²	75	56 Å²	56	33%	0.326	29%	0.293	S	S	.	.			trans	-143	142.6	176.8	176.2	178	178.4	-173.9	0	111.4	M394 N398 Y411	K355-M394 WeakPolarHBondContact O-CB 3.49Å; K355-M394 PolarHBondContact O-N 2.98Å; K355-N398 PolarHBondContact N-OD1 3.02Å; K355-N398 PolarHBondContact O-ND2 3.09Å; K355-Y411 HydrophobicContact CB-CD1 3.47Å; K355-Y411 VanDerWaalsContact CB-CD1 3.47Å; K355-Y411 HydrophobicContact CB-CD2 4.21Å; K355-Y411 HydrophobicContact CB-CE1 3.66Å; K355-Y411 HydrophobicContact CB-CE2 4.38Å; K355-Y411 HydrophobicContact CB-CG 3.74Å; K355-Y411 HydrophobicContact CD-CD1 3.87Å; K355-Y411 HydrophobicContact CD-CE1 4.26Å; K355-Y411 HydrophobicContact CG-CD1 4.22Å
356	W	84.8	Confident	76.3	Confident	22 Å²	22	63.4 Å²	63.4	8%	0.083	33%	0.332	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.7	132.7	166.5	-64.5	102.9	0	0	0	111.8	W378 V384 Y391 R392 A393 N398 A400 P402	W356-W378 HydrophobicContact CH2-CB 3.73Å; W356-W378 AromaticContact CH2-CD1 3.82Å; W356-W378 HydrophobicContact CH2-CD2 4.25Å; W356-W378 AromaticContact CH2-CG 3.62Å; W356-W378 HydrophobicContact CH2-CG 3.62Å; W356-W378 HydrophobicContact CZ2-CB 4.18Å; W356-W378 AromaticContact CZ2-CD1 3.7Å; W356-W378 AromaticContact CZ2-CG 3.96Å; W356-W378 HydrophobicContact CZ2-CG 3.96Å; W356-V384 HydrophobicContact CH2-CB 3.86Å; W356-V384 HydrophobicContact CH2-CG2 3.49Å; W356-V384 VanDerWaalsContact CH2-CG2 3.49Å; W356-V384 HydrophobicContact CZ3-CB 3.83Å; W356-V384 HydrophobicContact CZ3-CG2 3.71Å; W356-Y391 HydrophobicContact CB-CD1 3.93Å; W356-Y391 HydrophobicContact CB-CG 4.35Å; W356-R392 WeakPolarHBondContact CA-O 3.28Å; W356-A393 HydrophobicContact CE3-CB 4.38Å; W356-A393 HydrophobicContact CH2-CB 4.24Å; W356-A393 HydrophobicContact CZ3-CB 3.86Å; W356-N398 WeakPolarHBondContact CH2-ND2 3.25Å; W356-N398 HydrophobicContact CZ2-CB 4.42Å; W356-N398 WeakPolarHBondContact CZ2-ND2 3.48Å; W356-N398 WeakPolarHBondContact CZ3-ND2 3.39Å; W356-N398 PolarHBondContact NE1-OD1 3.28Å; W356-A400 PolarHBondContact NE1-O 3.4Å; W356-P402 HydrophobicContact CB-CB 4.43Å; W356-P402 HydrophobicContact CD2-CB 3.92Å; W356-P402 HydrophobicContact CG-CB 3.77Å
357	Q	83.9	Confident	75.1	Confident	93 Å²	93	64.9 Å²	64.9	44%	0.435	35%	0.345	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-99	122.9	164.6	-175.7	172	22.5	0	0	108.4	L359 Y391 R392 M394	Q357-L359 WeakPolarHBondContact O-CD1 3.38Å; Q357-L359 PolarHBondContact O-N 3.28Å; Q357-Y391 CarbonylContact O-C 3.53Å; Q357-Y391 VanDerWaalsContact O-CA 3.28Å; Q357-Y391 WeakPolarHBondContact O-CA 3.35Å; Q357-R392 PolarHBondContact N-O 2.77Å; Q357-R392 PolarHBondContact O-N 3.5Å; Q357-M394 HydrophobicContact CB-CG 3.84Å; Q357-M394 HydrophobicContact CB-SD 4.11Å; Q357-M394 PolarHBondContact OE1-SD 3.36Å
358	K	83.8	Confident	73.8	Confident	129 Å²	129	68.2 Å²	68.2	56%	0.561	37%	0.37	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-70.4	128.5	172.8	-172.3	176.5	177.4	177.5	0	108.9	C389 Y391	K358-C389 WeakPolarHBondContact CE-SG 3.27Å; K358-Y391 HydrophobicContact CB-CD1 4.01Å; K358-Y391 HydrophobicContact CB-CE1 3.78Å; K358-Y391 HydrophobicContact CD-CE1 4.44Å; K358-Y391 HydrophobicContact CG-CD1 4.43Å; K358-Y391 HydrophobicContact CG-CE1 3.97Å
359	L	79.4	Confident	73	Confident	25 Å²	25	70.1 Å²	70.1	13%	0.131	38%	0.379	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.1	142.1	172.5	-83.5	84	0	0	0	109.8	Q357 Y364 L383 L390 R392	Q357-L359 WeakPolarHBondContact O-CD1 3.38Å; Q357-L359 PolarHBondContact O-N 3.28Å; L359-Y364 HydrophobicContact CD2-CD2 3.89Å; L359-Y364 HydrophobicContact CD2-CE2 4.32Å; L359-L383 HydrophobicContact CD1-CD2 4.25Å; L359-L383 HydrophobicContact CD2-CD2 4.26Å; L359-L390 HydrophobicContact CB-CB 4.33Å; L359-L390 HydrophobicContact CB-CD2 4.08Å; L359-L390 HydrophobicContact CD2-CD2 4.04Å; L359-L390 HydrophobicContact CG-CD2 4.45Å; L359-L390 PolarHBondContact N-O 3.26Å; L359-R392 HydrophobicContact CD1-CB 3.33Å
360	E	76.5	Confident	72.5	Confident	170 Å²	170	73.5 Å²	73.5	79%	0.794	40%	0.395	S	S	*	.	P	Polyproline II helix	trans	-76	147.1	171.6	-63.4	-176.5	169.1	0	0	110.4	G362	E360-G362 PolarHBondContact O-N 3.32Å
361	H	58.3	Low	72.1	Confident	156 Å²	156	80.2 Å²	80.2	72%	0.722	43%	0.429	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.1	14	-164.1	-69.4	75.4	0	0	0	117.2	R388	H361-R388 PolarHBondContact NE2-O 3.12Å
362	G	61.2	Low	72	Confident	68 Å²	68	80.8 Å²	80.8	70%	0.701	43%	0.428	S	S	*	.	T	Hydrogen-bonded Turn	trans	-119.7	-8.3	-173.8	0	0	0	0	0	117.1	E360	E360-G362 PolarHBondContact O-N 3.32Å
363	S	57	Low	71.8	Confident	79 Å²	79	82.2 Å²	82.2	55%	0.552	44%	0.439	S	S	*	.	S	Bend	trans	-95.4	-25.3	-161	-62	0	0	0	0	116.8
364	Y	57.8	Low	71.5	Confident	144 Å²	144	87.6 Å²	87.6	57%	0.565	47%	0.465	S	S	*	.			trans	-151.6	80.3	-172.4	-65.7	-80	0	0	0	113.4	L359	L359-Y364 HydrophobicContact CD2-CD2 3.89Å; L359-Y364 HydrophobicContact CD2-CE2 4.32Å
365	S	55.6	Low	71.2	Confident	96 Å²	96	93.3 Å²	93.3	67%	0.671	50%	0.495	S	S	*	.	S	Bend	trans	-77.1	-21.7	177.6	-41.8	0	0	0	0	113.8
366	N	56.4	Low	70.9	Confident	164 Å²	164	92 Å²	92	88%	0.877	49%	0.493	S	S	*	.	S	Bend	trans	-109	3.7	-168.1	-63.8	-37.4	0	0	0	114.8
367	A	61.1	Low	70.6	Confident	31 Å²	31	93.1 Å²	93.1	26%	0.256	50%	0.5	S	S	.	.	S	Bend	trans	-84.3	142.6	175.1	0	0	0	0	0	110.2	Q369 L383	A367-Q369 WeakPolarHBondContact O-CG 3.46Å; A367-Q369 PolarHBondContact O-N 2.9Å; A367-Q369 VanDerWaalsContact O-N 3.09Å; A367-L383 HydrophobicContact CB-CD1 3.7Å
368	P	59.8	Low	70.5	Confident	106 Å²	106	89.1 Å²	89.1	69%	0.688	48%	0.482	S	S	*	.	P	Polyproline II helix	trans	-57.3	117.4	176.5	20.7	-29.7	0	0	0	110.1
369	Q	66.3	Low	70.3	Confident	82 Å²	82	84.4 Å²	84.4	38%	0.383	46%	0.464	S	S	.	.	P	Polyproline II helix	trans	-97	118.3	-177	-58.8	-178	15.3	0	0	109	A367 L390	A367-Q369 WeakPolarHBondContact O-CG 3.46Å; A367-Q369 PolarHBondContact O-N 2.9Å; A367-Q369 VanDerWaalsContact O-N 3.09Å; Q369-L390 HydrophobicContact CG-CD1 4.23Å
370	H	74.3	Confident	70.4	Confident	71 Å²	71	89.7 Å²	89.7	33%	0.329	49%	0.488	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-92	145.3	172.9	-64.5	-84	0	0	0	110.9	W378 L383 V384 R385	H370-W378 HydrophobicContact CB-CH2 3.47Å; H370-W378 VanDerWaalsContact CB-CH2 3.47Å; H370-W378 HydrophobicContact CB-CZ3 3.44Å; H370-W378 VanDerWaalsContact CB-CZ3 3.44Å; H370-W378 AromaticContact CG-CZ3 3.86Å; H370-L383 PolarHBondContact N-O 3.29Å; H370-V384 WeakPolarHBondContact O-CA 3.32Å; H370-R385 PolarHBondContact O-N 3.28Å
371	I	77.8	Confident	70.4	Confident	142 Å²	142	83.1 Å²	83.1	73%	0.728	47%	0.466	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-78.5	134.5	170.8	-62.2	169.3	0	0	0	107.6	W378	I371-W378 WeakPolarHBondContact O-CH2 3.29Å; I371-W378 WeakPolarHBondContact O-CZ2 3.21Å
372	W	81.8	Confident	71.5	Confident	28 Å²	28	77.3 Å²	77.3	11%	0.106	44%	0.441	C	S	.	.	P	Polyproline II helix	trans	-63.1	139.5	177.7	-173.5	72.2	0	0	0	110.9	E374 W378 V384 R385 H386 V401 P402	W372-E374 HydrophobicContact CE3-CG 4.39Å; W372-E374 HydrophobicContact CH2-CB 4.35Å; W372-E374 HydrophobicContact CH2-CG 3.23Å; W372-E374 HydrophobicContact CZ2-CG 4.03Å; W372-E374 HydrophobicContact CZ3-CG 3.43Å; W372-E374 VanDerWaalsContact CZ3-CG 3.43Å; W372-W378 AromaticContact CD1-NE1 3.58Å; W372-W378 AromaticContact NE1-NE1 3.9Å; W372-V384 HydrophobicContact CB-CG1 3.31Å; W372-V384 HydrophobicContact CG-CG1 4.01Å; W372-V384 VanDerWaalsContact N-CG1 3.27Å; W372-R385 PolarHBondContact N-O 3.21Å; W372-H386 HydrophobicContact CB-CB 4.16Å; W372-H386 AromaticContact CE3-CD2 3.65Å; W372-H386 AromaticContact CE3-NE2 3.85Å; W372-V401 HydrophobicContact CH2-CB 4.47Å; W372-V401 HydrophobicContact CH2-CG1 4.04Å; W372-V401 HydrophobicContact CH2-CG2 4.1Å; W372-V401 HydrophobicContact CZ2-CB 4.38Å; W372-V401 HydrophobicContact CZ2-CG1 4.31Å; W372-V401 HydrophobicContact CZ2-CG2 4.12Å; W372-P402 HydrophobicContact CB-CG 4.26Å; W372-P402 HydrophobicContact CD2-CG 3.81Å; W372-P402 HydrophobicContact CG-CG 3.6Å; W372-P402 VanDerWaalsContact NE1-CD 3.28Å
373	S	78.4	Confident	72.5	Confident	45 Å²	45	75.1 Å²	75.1	32%	0.315	41%	0.413	S	S	.	.			trans	-137	143.8	173.9	43.5	0	0	0	0	109.7	T376	S373-T376 WeakPolarHBondContact OG-CB 3.48Å; S373-T376 PolarHBondContact OG-OG1 3.2Å
374	E	77.5	Confident	73.6	Confident	114 Å²	114	71.3 Å²	71.3	53%	0.533	39%	0.387	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.9	-36.4	-175.7	-75.1	172.6	-176.5	0	0	111.9	P267 R271 W372 T376	P267-E374 WeakPolarHBondContact CB-O 3.21Å; R271-E374 VanDerWaalsContact CZ-O 3.24Å; R271-E374 PolarHBondContact NH1-O 2.92Å; R271-E374 PolarHBondContact NH2-O 3.27Å; W372-E374 HydrophobicContact CE3-CG 4.39Å; W372-E374 HydrophobicContact CH2-CB 4.35Å; W372-E374 HydrophobicContact CH2-CG 3.23Å; W372-E374 HydrophobicContact CZ2-CG 4.03Å; W372-E374 HydrophobicContact CZ3-CG 3.43Å; W372-E374 VanDerWaalsContact CZ3-CG 3.43Å; E374-T376 VanDerWaalsContact C-N 3.27Å; E374-T376 PolarHBondContact O-N 2.98Å
375	N	77.9	Confident	74.6	Confident	119 Å²	119	70.7 Å²	70.7	64%	0.636	38%	0.384	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.6	5.8	-172.1	-58.5	-5.3	0	0	0	113.4
376	T	78.5	Confident	75.7	Confident	48 Å²	48	68 Å²	68	29%	0.294	36%	0.36	S	S	.	.			trans	-112.6	131.5	-172.7	-44.4	0	0	0	0	111.1	S373 E374 W378	S373-T376 WeakPolarHBondContact OG-CB 3.48Å; S373-T376 PolarHBondContact OG-OG1 3.2Å; E374-T376 VanDerWaalsContact C-N 3.27Å; E374-T376 PolarHBondContact O-N 2.98Å; T376-W378 HydrophobicContact CG2-CZ2 4.4Å; T376-W378 VanDerWaalsContact O-CD1 3.31Å; T376-W378 PolarHBondContact O-NE1 3.02Å
377	I	79.5	Confident	76.4	Confident	45 Å²	45	64.1 Å²	64.1	23%	0.231	35%	0.346	C	S	.	.	P	Polyproline II helix	trans	-86.1	121	171.5	-57.2	174.3	0	0	0	108	P56 P267 Y397 V399	P56-I377 HydrophobicContact CG-CG2 3.82Å; P267-I377 HydrophobicContact CG-CD1 4.48Å; P267-I377 HydrophobicContact CG-CG1 3.75Å; I377-Y397 HydrophobicContact CD1-CD1 4.43Å; I377-Y397 HydrophobicContact CG2-CD1 3.51Å; I377-Y397 HydrophobicContact CG2-CE1 4.2Å; I377-Y397 HydrophobicContact CG2-CG 4.27Å; I377-V399 HydrophobicContact CG1-CG2 4.13Å; I377-V399 HydrophobicContact CG2-CG2 4.25Å
378	W	81.9	Confident	76.9	Confident	10 Å²	10	73 Å²	73	4%	0.038	37%	0.373	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.5	122.5	-178.1	-61.7	91.6	0	0	0	111	W356 H370 I371 W372 T376 V382 V384 N398	W356-W378 HydrophobicContact CH2-CB 3.73Å; W356-W378 AromaticContact CH2-CD1 3.82Å; W356-W378 HydrophobicContact CH2-CD2 4.25Å; W356-W378 AromaticContact CH2-CG 3.62Å; W356-W378 HydrophobicContact CH2-CG 3.62Å; W356-W378 HydrophobicContact CZ2-CB 4.18Å; W356-W378 AromaticContact CZ2-CD1 3.7Å; W356-W378 AromaticContact CZ2-CG 3.96Å; W356-W378 HydrophobicContact CZ2-CG 3.96Å; H370-W378 HydrophobicContact CB-CH2 3.47Å; H370-W378 VanDerWaalsContact CB-CH2 3.47Å; H370-W378 HydrophobicContact CB-CZ3 3.44Å; H370-W378 VanDerWaalsContact CB-CZ3 3.44Å; H370-W378 AromaticContact CG-CZ3 3.86Å; I371-W378 WeakPolarHBondContact O-CH2 3.29Å; I371-W378 WeakPolarHBondContact O-CZ2 3.21Å; W372-W378 AromaticContact CD1-NE1 3.58Å; W372-W378 AromaticContact NE1-NE1 3.9Å; T376-W378 HydrophobicContact CG2-CZ2 4.4Å; T376-W378 VanDerWaalsContact O-CD1 3.31Å; T376-W378 PolarHBondContact O-NE1 3.02Å; W378-V382 HydrophobicContact CE3-CB 4.36Å; W378-V382 HydrophobicContact CE3-CG1 3.62Å; W378-V382 HydrophobicContact CZ3-CG1 3.93Å; W378-V384 HydrophobicContact CD2-CG2 3.56Å; W378-V384 HydrophobicContact CE3-CG2 3.47Å; W378-V384 VanDerWaalsContact CE3-CG2 3.47Å; W378-V384 HydrophobicContact CG-CG2 4.22Å; W378-V384 HydrophobicContact CH2-CG2 4.05Å; W378-V384 HydrophobicContact CZ2-CG1 4.3Å; W378-V384 HydrophobicContact CZ2-CG2 4.13Å; W378-V384 HydrophobicContact CZ3-CG2 3.72Å; W378-N398 HydrophobicContact CB-CB 4.22Å; W378-N398 PolarHBondContact N-O 2.81Å; W378-N398 VanDerWaalsContact N-O 3.08Å; W378-N398 WeakPolarHBondContact O-CB 3.08Å; W378-N398 PolarHBondContact O-N 2.94Å
379	P	79.9	Confident	77.8	Confident	29 Å²	29	68.9 Å²	68.9	19%	0.188	35%	0.346	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-74.7	165.4	177.4	28.2	-30.5	0	0	0	111.6	G381 V382 A393	P379-G381 PolarHBondContact O-N 3.47Å; P379-V382 HydrophobicContact CG-CG2 3.67Å; P379-V382 WeakPolarHBondContact O-CG2 2.92Å; P379-V382 PolarHBondContact O-N 2.95Å; P379-A393 WeakPolarHBondContact O-CB 3.2Å
380	Q	80.8	Confident	78.4	Confident	136 Å²	136	66.3 Å²	66.3	64%	0.636	34%	0.335	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.8	134.7	-176.1	-166.8	175.9	26.9	0	0	112.4	V382 M394 G395	Q380-V382 VanDerWaalsContact C-N 3.33Å; Q380-V382 PolarHBondContact O-N 3.06Å; Q380-M394 PolarHBondContact NE2-O 3.41Å; Q380-M394 VanDerWaalsContact NE2-O 3.09Å; Q380-G395 VanDerWaalsContact CA-O 3.25Å; Q380-G395 WeakPolarHBondContact CA-O 3.44Å; Q380-G395 VanDerWaalsContact CB-O 3.3Å; Q380-G395 WeakPolarHBondContact CB-O 3.41Å; Q380-G395 PolarHBondContact N-O 3.46Å
381	G	77.1	Confident	78.7	Confident	32 Å²	32	64 Å²	64	33%	0.33	32%	0.324	S	S	.	.	T	Hydrogen-bonded Turn	trans	86.7	-9.4	174.5	0	0	0	0	0	115.4	P379 A393	P379-G381 PolarHBondContact O-N 3.47Å; G381-A393 WeakPolarHBondContact CA-O 3.06Å; G381-A393 PolarHBondContact N-O 3.36Å
382	V	81.5	Confident	78.9	Confident	35 Å²	35	62.5 Å²	62.5	21%	0.212	31%	0.309	C	S	.	.			trans	-67.3	139.3	178.7	-179.7	0	0	0	0	111.4	W378 P379 Q380 V384 R392 A393	W378-V382 HydrophobicContact CE3-CB 4.36Å; W378-V382 HydrophobicContact CE3-CG1 3.62Å; W378-V382 HydrophobicContact CZ3-CG1 3.93Å; P379-V382 HydrophobicContact CG-CG2 3.67Å; P379-V382 WeakPolarHBondContact O-CG2 2.92Å; P379-V382 PolarHBondContact O-N 2.95Å; Q380-V382 VanDerWaalsContact C-N 3.33Å; Q380-V382 PolarHBondContact O-N 3.06Å; V382-V384 HydrophobicContact CG1-CG2 4.1Å; V382-R392 WeakPolarHBondContact O-CA 3.43Å; V382-A393 PolarHBondContact O-N 3.32Å
383	L	80.9	Confident	79	Confident	21 Å²	21	61.2 Å²	61.2	11%	0.11	30%	0.304	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.2	124.6	177.9	-62.7	173.9	0	0	0	109.8	L359 A367 H370 L390 Y391 R392	L359-L383 HydrophobicContact CD1-CD2 4.25Å; L359-L383 HydrophobicContact CD2-CD2 4.26Å; A367-L383 HydrophobicContact CB-CD1 3.7Å; H370-L383 PolarHBondContact N-O 3.29Å; L383-L390 HydrophobicContact CB-CD2 4.33Å; L383-L390 HydrophobicContact CD1-CD2 4.23Å; L383-L390 HydrophobicContact CD2-CD2 3.87Å; L383-L390 HydrophobicContact CG-CD2 4.37Å; L383-Y391 WeakPolarHBondContact CA-O 3.44Å; L383-R392 HydrophobicContact CD2-CB 3.69Å; L383-R392 HydrophobicContact CD2-CG 4Å
384	V	80.8	Confident	79	Confident	0 Å²	0	62.8 Å²	62.8	0%	0	31%	0.307	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-126.6	137.1	-177.3	-176.2	0	0	0	0	110.1	W356 H370 W372 W378 V382 Y391	W356-V384 HydrophobicContact CH2-CB 3.86Å; W356-V384 HydrophobicContact CH2-CG2 3.49Å; W356-V384 VanDerWaalsContact CH2-CG2 3.49Å; W356-V384 HydrophobicContact CZ3-CB 3.83Å; W356-V384 HydrophobicContact CZ3-CG2 3.71Å; H370-V384 WeakPolarHBondContact O-CA 3.32Å; W372-V384 HydrophobicContact CB-CG1 3.31Å; W372-V384 HydrophobicContact CG-CG1 4.01Å; W372-V384 VanDerWaalsContact N-CG1 3.27Å; W378-V384 HydrophobicContact CD2-CG2 3.56Å; W378-V384 HydrophobicContact CE3-CG2 3.47Å; W378-V384 VanDerWaalsContact CE3-CG2 3.47Å; W378-V384 HydrophobicContact CG-CG2 4.22Å; W378-V384 HydrophobicContact CH2-CG2 4.05Å; W378-V384 HydrophobicContact CZ2-CG1 4.3Å; W378-V384 HydrophobicContact CZ2-CG2 4.13Å; W378-V384 HydrophobicContact CZ3-CG2 3.72Å; V382-V384 HydrophobicContact CG1-CG2 4.1Å; V384-Y391 PolarHBondContact N-O 3.28Å; V384-Y391 PolarHBondContact O-N 3.24Å
385	R	78.7	Confident	78.9	Confident	131 Å²	131	57.4 Å²	57.4	49%	0.494	28%	0.282	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.2	125.3	175.3	-169.9	179.1	178.4	118.7	-1.8	110.2	H370 W372	H370-R385 PolarHBondContact O-N 3.28Å; W372-R385 PolarHBondContact N-O 3.21Å
386	H	78	Confident	78.7	Confident	40 Å²	40	55 Å²	55	19%	0.185	27%	0.274	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-145.7	137.1	174.8	-173.7	-107.6	0	0	0	110.3	W372 R388 C389 Y391 P402	W372-H386 HydrophobicContact CB-CB 4.16Å; W372-H386 AromaticContact CE3-CD2 3.65Å; W372-H386 AromaticContact CE3-NE2 3.85Å; H386-R388 VanDerWaalsContact C-N 3.32Å; H386-R388 PolarHBondContact O-N 2.93Å; H386-R388 VanDerWaalsContact O-N 3.15Å; H386-C389 PolarHBondContact N-O 3.44Å; H386-C389 PolarHBondContact O-N 3.34Å; H386-Y391 HydrophobicContact CB-CD2 4.07Å; H386-Y391 HydrophobicContact CB-CE2 4.04Å; H386-Y391 WeakPolarHBondContact O-CE2 3.49Å; H386-P402 HydrophobicContact CB-CB 4.03Å; H386-P402 HydrophobicContact CB-CG 3.58Å; H386-P402 PolarHBondContact ND1-O 3.41Å
387	S	72.3	Confident	78.6	Confident	82 Å²	82	54 Å²	54	57%	0.573	27%	0.265	S	S	*	.	T	Hydrogen-bonded Turn	trans	44.4	48.5	179.4	-51.5	0	0	0	0	115	C389	S387-C389 PolarHBondContact O-N 2.9Å; S387-C389 VanDerWaalsContact O-N 3.07Å
388	R	72.1	Confident	78.7	Confident	217 Å²	217	51.9 Å²	51.9	82%	0.819	25%	0.254	S	S	*	.	T	Hydrogen-bonded Turn	trans	61.7	8.4	-178.8	-53.5	-178.7	180	178.2	0.1	115.9	H361 H386	H361-R388 PolarHBondContact NE2-O 3.12Å; H386-R388 VanDerWaalsContact C-N 3.32Å; H386-R388 PolarHBondContact O-N 2.93Å; H386-R388 VanDerWaalsContact O-N 3.15Å
389	C	77.1	Confident	78.7	Confident	20 Å²	20	51.4 Å²	51.4	14%	0.135	25%	0.252	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.1	154.3	174	-62.7	0	0	0	0	110.4	K358 H386 S387 Y391	K358-C389 WeakPolarHBondContact CE-SG 3.27Å; H386-C389 PolarHBondContact N-O 3.44Å; H386-C389 PolarHBondContact O-N 3.34Å; S387-C389 PolarHBondContact O-N 2.9Å; S387-C389 VanDerWaalsContact O-N 3.07Å; C389-Y391 HydrophobicContact CB-CD2 4.39Å; C389-Y391 HydrophobicContact CB-CE2 3.66Å
390	L	79.6	Confident	78.8	Confident	27 Å²	27	50.2 Å²	50.2	14%	0.141	24%	0.244	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-99.1	133.9	173.8	-160	101.7	0	0	0	108.8	L359 Q369 L383	L359-L390 HydrophobicContact CB-CB 4.33Å; L359-L390 HydrophobicContact CB-CD2 4.08Å; L359-L390 HydrophobicContact CD2-CD2 4.04Å; L359-L390 HydrophobicContact CG-CD2 4.45Å; L359-L390 PolarHBondContact N-O 3.26Å; Q369-L390 HydrophobicContact CG-CD1 4.23Å; L383-L390 HydrophobicContact CB-CD2 4.33Å; L383-L390 HydrophobicContact CD1-CD2 4.23Å; L383-L390 HydrophobicContact CD2-CD2 3.87Å; L383-L390 HydrophobicContact CG-CD2 4.37Å
391	Y	81.3	Confident	78.9	Confident	23 Å²	23	45.6 Å²	45.6	9%	0.09	23%	0.225	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-124.7	140.9	179.1	-64.6	-87	0	0	0	110.3	W356 Q357 K358 L383 V384 H386 C389 P402	W356-Y391 HydrophobicContact CB-CD1 3.93Å; W356-Y391 HydrophobicContact CB-CG 4.35Å; Q357-Y391 CarbonylContact O-C 3.53Å; Q357-Y391 VanDerWaalsContact O-CA 3.28Å; Q357-Y391 WeakPolarHBondContact O-CA 3.35Å; K358-Y391 HydrophobicContact CB-CD1 4.01Å; K358-Y391 HydrophobicContact CB-CE1 3.78Å; K358-Y391 HydrophobicContact CD-CE1 4.44Å; K358-Y391 HydrophobicContact CG-CD1 4.43Å; K358-Y391 HydrophobicContact CG-CE1 3.97Å; L383-Y391 WeakPolarHBondContact CA-O 3.44Å; V384-Y391 PolarHBondContact N-O 3.28Å; V384-Y391 PolarHBondContact O-N 3.24Å; H386-Y391 HydrophobicContact CB-CD2 4.07Å; H386-Y391 HydrophobicContact CB-CE2 4.04Å; H386-Y391 WeakPolarHBondContact O-CE2 3.49Å; C389-Y391 HydrophobicContact CB-CD2 4.39Å; C389-Y391 HydrophobicContact CB-CE2 3.66Å; Y391-P402 HydrophobicContact CD1-CB 4.36Å; Y391-P402 HydrophobicContact CD2-CB 3.77Å; Y391-P402 HydrophobicContact CE2-CB 4.1Å; Y391-P402 WeakPolarHBondContact CE2-O 3.44Å; Y391-P402 HydrophobicContact CG-CB 3.89Å; Y391-P402 PolarHBondContact OH-O 3.34Å
392	R	81.8	Confident	78.8	Confident	111 Å²	111	44.1 Å²	44.1	42%	0.419	21%	0.21	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-107.7	134.2	174.1	-178.9	178.5	-177.2	-174.1	0.4	110.6	W356 Q357 L359 V382 L383 M394	W356-R392 WeakPolarHBondContact CA-O 3.28Å; Q357-R392 PolarHBondContact N-O 2.77Å; Q357-R392 PolarHBondContact O-N 3.5Å; L359-R392 HydrophobicContact CD1-CB 3.33Å; V382-R392 WeakPolarHBondContact O-CA 3.43Å; L383-R392 HydrophobicContact CD2-CB 3.69Å; L383-R392 HydrophobicContact CD2-CG 4Å; R392-M394 PolarHBondContact O-N 2.93Å
393	A	83.3	Confident	78.6	Confident	1 Å²	1	45.7 Å²	45.7	1%	0.008	22%	0.222	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-72.8	122.5	173	0	0	0	0	0	111.1	W356 P379 G381 V382 N398	W356-A393 HydrophobicContact CE3-CB 4.38Å; W356-A393 HydrophobicContact CH2-CB 4.24Å; W356-A393 HydrophobicContact CZ3-CB 3.86Å; P379-A393 WeakPolarHBondContact O-CB 3.2Å; G381-A393 WeakPolarHBondContact CA-O 3.06Å; G381-A393 PolarHBondContact N-O 3.36Å; V382-A393 PolarHBondContact O-N 3.32Å; A393-N398 VanDerWaalsContact CA-ND2 3.3Å; A393-N398 WeakPolarHBondContact CA-ND2 3.08Å; A393-N398 HydrophobicContact CB-CB 3.89Å; A393-N398 VanDerWaalsContact CB-ND2 3.31Å; A393-N398 WeakPolarHBondContact CB-ND2 3.5Å
394	M	79.1	Confident	78.7	Confident	77 Å²	77	47.3 Å²	47.3	38%	0.379	23%	0.231	S	C	.	.			trans	-97.3	-26.8	-178.4	-68.4	-65	-70.2	0	0	113.7	K355 Q357 Q380 R392	K355-M394 WeakPolarHBondContact O-CB 3.49Å; K355-M394 PolarHBondContact O-N 2.98Å; Q357-M394 HydrophobicContact CB-CG 3.84Å; Q357-M394 HydrophobicContact CB-SD 4.11Å; Q357-M394 PolarHBondContact OE1-SD 3.36Å; Q380-M394 PolarHBondContact NE2-O 3.41Å; Q380-M394 VanDerWaalsContact NE2-O 3.09Å; R392-M394 PolarHBondContact O-N 2.93Å
395	G	75.6	Confident	78.8	Confident	1 Å²	1	52 Å²	52	1%	0.01	26%	0.26	C	S	.	.	S	Bend	trans	-93.7	164.9	-178	0	0	0	0	0	113.4	Q380 Y397	Q380-G395 VanDerWaalsContact CA-O 3.25Å; Q380-G395 WeakPolarHBondContact CA-O 3.44Å; Q380-G395 VanDerWaalsContact CB-O 3.3Å; Q380-G395 WeakPolarHBondContact CB-O 3.41Å; Q380-G395 PolarHBondContact N-O 3.46Å; G395-Y397 VanDerWaalsContact C-N 3.28Å
396	P	73.5	Confident	78.8	Confident	70 Å²	70	47.4 Å²	47.4	46%	0.455	25%	0.247	S	C	.	.	S	Bend	trans	-63.9	-35.8	173.9	26.3	-32.9	0	0	0	112
397	Y	75.8	Confident	79.1	Confident	27 Å²	27	46 Å²	46	11%	0.106	24%	0.241	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-116.2	136.1	167.7	-71	-107.1	0	0	0	107.5	P56 G57 P58 V59 H352 G354 I377 G395	P56-Y397 HydrophobicContact CB-CD1 4.41Å; P56-Y397 HydrophobicContact CB-CD2 4.42Å; P56-Y397 HydrophobicContact CB-CE1 4.02Å; P56-Y397 HydrophobicContact CB-CE2 4.07Å; P56-Y397 HydrophobicContact CG-CD1 3.99Å; P56-Y397 HydrophobicContact CG-CE1 3.59Å; P56-Y397 PolarHBondContact O-OH 3.28Å; G57-Y397 WeakPolarHBondContact O-CE2 3.43Å; G57-Y397 PolarHBondContact O-OH 3.21Å; P58-Y397 WeakPolarHBondContact CA-OH 3.48Å; V59-Y397 HydrophobicContact CB-CD2 4.48Å; V59-Y397 HydrophobicContact CB-CE2 4.25Å; V59-Y397 HydrophobicContact CG2-CD2 3.11Å; V59-Y397 HydrophobicContact CG2-CE2 3.19Å; V59-Y397 HydrophobicContact CG2-CG 3.83Å; H352-Y397 WeakPolarHBondContact O-CB 3.34Å; G354-Y397 WeakPolarHBondContact CA-O 3.19Å; I377-Y397 HydrophobicContact CD1-CD1 4.43Å; I377-Y397 HydrophobicContact CG2-CD1 3.51Å; I377-Y397 HydrophobicContact CG2-CE1 4.2Å; I377-Y397 HydrophobicContact CG2-CG 4.27Å; G395-Y397 VanDerWaalsContact C-N 3.28Å
398	N	81.7	Confident	79.6	Confident	0 Å²	0	43.8 Å²	43.8	0%	0	23%	0.228	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-136.9	105.8	173.9	-165.2	18.6	0	0	0	110.1	L353 K355 W356 W378 A393	L353-N398 PolarHBondContact O-OD1 2.88Å; K355-N398 PolarHBondContact N-OD1 3.02Å; K355-N398 PolarHBondContact O-ND2 3.09Å; W356-N398 WeakPolarHBondContact CH2-ND2 3.25Å; W356-N398 HydrophobicContact CZ2-CB 4.42Å; W356-N398 WeakPolarHBondContact CZ2-ND2 3.48Å; W356-N398 WeakPolarHBondContact CZ3-ND2 3.39Å; W356-N398 PolarHBondContact NE1-OD1 3.28Å; W378-N398 HydrophobicContact CB-CB 4.22Å; W378-N398 PolarHBondContact N-O 2.81Å; W378-N398 VanDerWaalsContact N-O 3.08Å; W378-N398 WeakPolarHBondContact O-CB 3.08Å; W378-N398 PolarHBondContact O-N 2.94Å; A393-N398 VanDerWaalsContact CA-ND2 3.3Å; A393-N398 WeakPolarHBondContact CA-ND2 3.08Å; A393-N398 HydrophobicContact CB-CB 3.89Å; A393-N398 VanDerWaalsContact CB-ND2 3.31Å; A393-N398 WeakPolarHBondContact CB-ND2 3.5Å
399	V	82.3	Confident	80.2	Confident	0 Å²	0	42.2 Å²	42.2	0%	0	22%	0.222	C	C	.	.			trans	-116.8	-15.8	-175.9	176.4	0	0	0	0	110.8	P267 I270 R271 L353 I377	P267-V399 HydrophobicContact CB-CG1 3.77Å; P267-V399 VanDerWaalsContact O-CG1 3.31Å; P267-V399 WeakPolarHBondContact O-CG1 3.46Å; I270-V399 HydrophobicContact CB-CG1 4.32Å; I270-V399 HydrophobicContact CD1-CG2 4.16Å; I270-V399 HydrophobicContact CG2-CG1 4.38Å; R271-V399 HydrophobicContact CG-CG1 3.95Å; R271-V399 VanDerWaalsContact CZ-O 3.27Å; R271-V399 PolarHBondContact NE-O 3.03Å; R271-V399 PolarHBondContact NH2-O 3.27Å; L353-V399 PolarHBondContact O-N 3.48Å; I377-V399 HydrophobicContact CG1-CG2 4.13Å; I377-V399 HydrophobicContact CG2-CG2 4.25Å
400	A	82.2	Confident	80.7	Confident	3 Å²	3	41.7 Å²	41.7	3%	0.025	22%	0.217	C	C	.	.	S	Bend	trans	-50.1	153	178	0	0	0	0	0	113.1	L353 W356 P402 H407	L353-A400 HydrophobicContact CD1-CB 4Å; L353-A400 HydrophobicContact CG-CB 4.05Å; L353-A400 PolarHBondContact O-N 3.07Å; W356-A400 PolarHBondContact NE1-O 3.4Å; A400-P402 WeakPolarHBondContact O-CD 3.29Å; A400-H407 HydrophobicContact CB-CB 4.18Å
401	V	83.1	Confident	80.9	Confident	40 Å²	40	41.3 Å²	41.3	24%	0.242	21%	0.214	C	C	.	.			trans	-79.8	121.9	173.4	-179	0	0	0	0	109.3	W372 S403 D404 H407	W372-V401 HydrophobicContact CH2-CB 4.47Å; W372-V401 HydrophobicContact CH2-CG1 4.04Å; W372-V401 HydrophobicContact CH2-CG2 4.1Å; W372-V401 HydrophobicContact CZ2-CB 4.38Å; W372-V401 HydrophobicContact CZ2-CG1 4.31Å; W372-V401 HydrophobicContact CZ2-CG2 4.12Å; V401-S403 VanDerWaalsContact C-N 3.28Å; V401-S403 PolarHBondContact O-N 2.88Å; V401-D404 HydrophobicContact CB-CB 4.37Å; V401-D404 PolarHBondContact O-N 2.74Å; V401-H407 PolarHBondContact N-ND1 3.4Å
402	P	75.4	Confident	81.1	Confident	0 Å²	0	46.2 Å²	46.2	0%	0	24%	0.236	C	C	.	.	T	Hydrogen-bonded Turn	trans	-74.1	73.7	-175.3	26.6	-31.7	0	0	0	112.9	W356 W372 H386 Y391 A400	W356-P402 HydrophobicContact CB-CB 4.43Å; W356-P402 HydrophobicContact CD2-CB 3.92Å; W356-P402 HydrophobicContact CG-CB 3.77Å; W372-P402 HydrophobicContact CB-CG 4.26Å; W372-P402 HydrophobicContact CD2-CG 3.81Å; W372-P402 HydrophobicContact CG-CG 3.6Å; W372-P402 VanDerWaalsContact NE1-CD 3.28Å; H386-P402 HydrophobicContact CB-CB 4.03Å; H386-P402 HydrophobicContact CB-CG 3.58Å; H386-P402 PolarHBondContact ND1-O 3.41Å; Y391-P402 HydrophobicContact CD1-CB 4.36Å; Y391-P402 HydrophobicContact CD2-CB 3.77Å; Y391-P402 HydrophobicContact CE2-CB 4.1Å; Y391-P402 WeakPolarHBondContact CE2-O 3.44Å; Y391-P402 HydrophobicContact CG-CB 3.89Å; Y391-P402 PolarHBondContact OH-O 3.34Å; A400-P402 WeakPolarHBondContact O-CD 3.29Å
403	S	77.2	Confident	81.2	Confident	68 Å²	68	43.4 Å²	43.4	48%	0.476	23%	0.229	S	C	.	.	T	Hydrogen-bonded Turn	trans	167.7	-16.7	171.6	46.1	0	0	0	0	110.6	V401 V405	V401-S403 VanDerWaalsContact C-N 3.28Å; V401-S403 PolarHBondContact O-N 2.88Å; S403-V405 PolarHBondContact O-N 3.19Å
404	D	81.9	Confident	81.3	Confident	55 Å²	55	43.9 Å²	43.9	29%	0.294	23%	0.231	S	C	.	.			trans	-75.5	117.6	-178.5	-174.5	16.3	0	0	0	111.7	V401 S406 H407 A408	V401-D404 HydrophobicContact CB-CB 4.37Å; V401-D404 PolarHBondContact O-N 2.74Å; D404-S406 PolarHBondContact O-N 3.32Å; D404-S406 WeakPolarHBondContact OD1-CB 3.44Å; D404-S406 PolarHBondContact OD1-N 2.76Å; D404-S406 PolarHBondContact OD1-OG 3.22Å; D404-S406 WeakPolarHBondContact OD2-CB 3.46Å; D404-S406 PolarHBondContact OD2-OG 2.94Å; D404-H407 HydrophobicContact CB-CB 4.46Å; D404-H407 IonicContact OD2-CD2 3.93Å; D404-H407 PolarHBondContact OD2-CD2 2.91Å; D404-H407 IonicContact OD2-CE1 2.67Å; D404-H407 IonicContact OD2-CG 3.49Å; D404-H407 PolarHBondContact OD2-N 2.93Å; D404-H407 IonicContact OD2-ND1 2.86Å; D404-H407 IonicContact OD2-NE2 2.74Å; D404-H407 PolarHBondContact OD2-NE2 2.79Å; D404-A408 PolarHBondContact O-N 3.13Å
405	V	82.2	Confident	81.5	Confident	100 Å²	100	43.6 Å²	43.6	61%	0.606	23%	0.229	S	C	*	.	H	α-helix	trans	-68.1	-28.1	176	-176	0	0	0	0	110.6	S403 A408 R409	S403-V405 PolarHBondContact O-N 3.19Å; V405-A408 PolarHBondContact O-N 3.04Å; V405-R409 HydrophobicContact CG1-CG 4.23Å; V405-R409 WeakPolarHBondContact O-CB 3.42Å; V405-R409 VanDerWaalsContact O-CG 3.31Å; V405-R409 WeakPolarHBondContact O-CG 3.49Å; V405-R409 PolarHBondContact O-N 3.34Å
406	S	80.3	Confident	81.8	Confident	33 Å²	33	51.7 Å²	51.7	23%	0.231	26%	0.259	C	S	.	.	H	α-helix	trans	-67.7	-45.5	-177.9	99.6	0	0	0	0	111.4	K278 D404 A408 R409 F410	K278-S406 PolarHBondContact NZ-OG 2.82Å; D404-S406 PolarHBondContact O-N 3.32Å; D404-S406 WeakPolarHBondContact OD1-CB 3.44Å; D404-S406 PolarHBondContact OD1-N 2.76Å; D404-S406 PolarHBondContact OD1-OG 3.22Å; D404-S406 WeakPolarHBondContact OD2-CB 3.46Å; D404-S406 PolarHBondContact OD2-OG 2.94Å; S406-A408 VanDerWaalsContact C-N 3.35Å; S406-A408 PolarHBondContact O-N 3.2Å; S406-R409 PolarHBondContact O-N 2.85Å; S406-F410 WeakPolarHBondContact O-CB 3.22Å; S406-F410 PolarHBondContact O-N 3.35Å
407	H	83.4	Confident	81.9	Confident	11 Å²	11	49.5 Å²	49.5	5%	0.051	24%	0.244	C	C	.	.	H	α-helix	trans	-63.3	-39.9	173.1	-68.8	-176.9	0	0	0	111.9	E275 L353 A400 V401 D404 R409 F410 Y411	E275-H407 IonicContact OE1-CD2 3.89Å; E275-H407 PolarHBondContact OE1-CD2 2.99Å; E275-H407 IonicContact OE1-NE2 2.61Å; E275-H407 PolarHBondContact OE1-NE2 3.06Å; L353-H407 HydrophobicContact CD2-CB 4.12Å; A400-H407 HydrophobicContact CB-CB 4.18Å; V401-H407 PolarHBondContact N-ND1 3.4Å; D404-H407 HydrophobicContact CB-CB 4.46Å; D404-H407 IonicContact OD2-CD2 3.93Å; D404-H407 PolarHBondContact OD2-CD2 2.91Å; D404-H407 IonicContact OD2-CE1 2.67Å; D404-H407 IonicContact OD2-CG 3.49Å; D404-H407 PolarHBondContact OD2-N 2.93Å; D404-H407 IonicContact OD2-ND1 2.86Å; D404-H407 IonicContact OD2-NE2 2.74Å; D404-H407 PolarHBondContact OD2-NE2 2.79Å; H407-R409 PolarHBondContact O-N 2.98Å; H407-F410 PolarHBondContact O-N 3.45Å; H407-Y411 WeakPolarHBondContact O-CB 3.4Å; H407-Y411 PolarHBondContact O-N 3.37Å
408	A	83.3	Confident	82.3	Confident	36 Å²	36	50.1 Å²	50.1	30%	0.298	25%	0.25	S	C	.	.	H	α-helix	trans	-64.4	-39.7	176.9	0	0	0	0	0	112.8	D404 V405 S406 F412	D404-A408 PolarHBondContact O-N 3.13Å; V405-A408 PolarHBondContact O-N 3.04Å; S406-A408 VanDerWaalsContact C-N 3.35Å; S406-A408 PolarHBondContact O-N 3.2Å; A408-F412 WeakPolarHBondContact O-CB 3.22Å; A408-F412 PolarHBondContact O-N 2.92Å
409	R	85.3	Confident	82.5	Confident	184 Å²	184	53.2 Å²	53.2	69%	0.694	26%	0.261	S	S	*	.	H	α-helix	trans	-69.3	-42.2	175.9	-73.1	178	77.6	179.2	4.5	111.7	V405 S406 H407 F412 L413	V405-R409 HydrophobicContact CG1-CG 4.23Å; V405-R409 WeakPolarHBondContact O-CB 3.42Å; V405-R409 VanDerWaalsContact O-CG 3.31Å; V405-R409 WeakPolarHBondContact O-CG 3.49Å; V405-R409 PolarHBondContact O-N 3.34Å; S406-R409 PolarHBondContact O-N 2.85Å; H407-R409 PolarHBondContact O-N 2.98Å; R409-F412 PolarHBondContact O-N 2.88Å; R409-L413 WeakPolarHBondContact O-CB 3.23Å; R409-L413 PolarHBondContact O-N 2.96Å
410	F	86.4	Confident	82.8	Confident	8 Å²	8	54.3 Å²	54.3	4%	0.035	27%	0.267	C	S	.	.	H	α-helix	trans	-59.5	-51.3	176.2	-174.2	-90.9	0	0	0	110.9	V274 L277 K278 L346 A350 L353 S406 H407 F412 L413 F414	V274-F410 HydrophobicContact CG1-CD1 3.89Å; V274-F410 HydrophobicContact CG1-CD2 4.46Å; V274-F410 HydrophobicContact CG1-CE1 3.98Å; V274-F410 HydrophobicContact CG1-CG 4.14Å; V274-F410 HydrophobicContact CG1-CZ 4.32Å; V274-F410 HydrophobicContact CG2-CE1 4.16Å; L277-F410 HydrophobicContact CB-CZ 4.49Å; K278-F410 HydrophobicContact CB-CD2 4.29Å; K278-F410 HydrophobicContact CB-CE2 4.48Å; L346-F410 HydrophobicContact CD2-CE2 3.85Å; L346-F410 HydrophobicContact CD2-CZ 3.81Å; A350-F410 HydrophobicContact CB-CD1 4.18Å; A350-F410 HydrophobicContact CB-CE1 3.86Å; L353-F410 HydrophobicContact CD2-CD1 3.91Å; S406-F410 WeakPolarHBondContact O-CB 3.22Å; S406-F410 PolarHBondContact O-N 3.35Å; H407-F410 PolarHBondContact O-N 3.45Å; F410-F412 VanDerWaalsContact C-N 3.34Å; F410-F412 PolarHBondContact O-N 3.15Å; F410-L413 PolarHBondContact O-N 3.44Å; F410-F414 HydrophobicContact CD1-CD2 4.09Å; F410-F414 AromaticContact CD2-CD2 3.55Å; F410-F414 HydrophobicContact CD2-CD2 3.55Å; F410-F414 AromaticContact CD2-CE2 3.46Å; F410-F414 HydrophobicContact CD2-CE2 3.46Å; F410-F414 VanDerWaalsContact CD2-CE2 3.46Å; F410-F414 HydrophobicContact CE1-CD2 4.07Å; F410-F414 AromaticContact CE2-CD2 3.52Å; F410-F414 HydrophobicContact CE2-CD2 3.52Å; F410-F414 AromaticContact CE2-CE2 3.49Å; F410-F414 HydrophobicContact CE2-CE2 3.49Å; F410-F414 VanDerWaalsContact CE2-CE2 3.49Å; F410-F414 AromaticContact CG-CD2 3.84Å; F410-F414 HydrophobicContact CG-CD2 3.84Å; F410-F414 HydrophobicContact CG-CE2 4.16Å; F410-F414 AromaticContact CZ-CD2 3.79Å; F410-F414 HydrophobicContact CZ-CD2 3.79Å; F410-F414 HydrophobicContact CZ-CE2 4.2Å; F410-F414 WeakPolarHBondContact O-CD2 3.2Å; F410-F414 PolarHBondContact O-N 3.48Å
411	Y	84.7	Confident	83.1	Confident	20 Å²	20	55.3 Å²	55.3	8%	0.078	27%	0.272	C	S	.	.	H	α-helix	trans	-59.7	-44.5	175.4	-174.4	-88.7	0	0	0	111.6	A350 G354 K355 H407 L413 H415	A350-Y411 VanDerWaalsContact O-CD2 3.22Å; A350-Y411 WeakPolarHBondContact O-CD2 3.38Å; A350-Y411 WeakPolarHBondContact O-CE2 3.48Å; G354-Y411 VanDerWaalsContact C-CE2 3.49Å; G354-Y411 VanDerWaalsContact CA-CE2 3.46Å; G354-Y411 WeakPolarHBondContact O-CD2 3.21Å; K355-Y411 HydrophobicContact CB-CD1 3.47Å; K355-Y411 VanDerWaalsContact CB-CD1 3.47Å; K355-Y411 HydrophobicContact CB-CD2 4.21Å; K355-Y411 HydrophobicContact CB-CE1 3.66Å; K355-Y411 HydrophobicContact CB-CE2 4.38Å; K355-Y411 HydrophobicContact CB-CG 3.74Å; K355-Y411 HydrophobicContact CD-CD1 3.87Å; K355-Y411 HydrophobicContact CD-CE1 4.26Å; K355-Y411 HydrophobicContact CG-CD1 4.22Å; H407-Y411 WeakPolarHBondContact O-CB 3.4Å; H407-Y411 PolarHBondContact O-N 3.37Å; Y411-L413 PolarHBondContact O-N 3.12Å; Y411-H415 HydrophobicContact CD1-CB 3.93Å; Y411-H415 HydrophobicContact CD2-CB 4.37Å; Y411-H415 HydrophobicContact CE1-CB 3.77Å; Y411-H415 AromaticContact CE1-CD2 3.96Å; Y411-H415 AromaticContact CE1-CG 3.6Å; Y411-H415 AromaticContact CE1-ND1 3.91Å; Y411-H415 HydrophobicContact CE2-CB 4.22Å; Y411-H415 AromaticContact CE2-ND1 3.68Å; Y411-H415 HydrophobicContact CG-CB 4.26Å; Y411-H415 AromaticContact CZ-CE1 3.75Å; Y411-H415 AromaticContact CZ-CG 3.5Å; Y411-H415 AromaticContact CZ-ND1 3.29Å; Y411-H415 VanDerWaalsContact CZ-ND1 3.29Å; Y411-H415 WeakPolarHBondContact O-CA 3.38Å; Y411-H415 WeakPolarHBondContact O-CB 3.33Å; Y411-H415 PolarHBondContact O-N 3.41Å; Y411-H415 PolarHBondContact OH-CE1 3.36Å; Y411-H415 PolarHBondContact OH-ND1 3.21Å; Y411-H415 VanDerWaalsContact OH-ND1 3.1Å
412	F	85.9	Confident	83.5	Confident	126 Å²	126	56.6 Å²	56.6	55%	0.553	28%	0.277	S	S	*	.	H	α-helix	trans	-57.1	-50.6	177.2	178.5	-99.6	0	0	0	111	A408 R409 F410 R419	A408-F412 WeakPolarHBondContact O-CB 3.22Å; A408-F412 PolarHBondContact O-N 2.92Å; R409-F412 PolarHBondContact O-N 2.88Å; F410-F412 VanDerWaalsContact C-N 3.34Å; F410-F412 PolarHBondContact O-N 3.15Å; F412-R419 VanDerWaalsContact CD1-NH1 3.28Å; F412-R419 VanDerWaalsContact CG-NH1 3.32Å; F412-R419 PolarHBondContact O-NE 3.06Å; F412-R419 PolarHBondContact O-NH1 3.26Å; F412-R419 PolarHBondContact O-NH2 3.01Å
413	L	83.4	Confident	84.2	Confident	52 Å²	52	60.8 Å²	60.8	27%	0.272	30%	0.299	S	S	.	.	H	α-helix	trans	-65.3	-43.2	-174.9	-170	60.5	0	0	0	112.8	F281 R409 F410 Y411	F281-L413 HydrophobicContact CE1-CD2 4.11Å; F281-L413 HydrophobicContact CZ-CD2 3.85Å; R409-L413 WeakPolarHBondContact O-CB 3.23Å; R409-L413 PolarHBondContact O-N 2.96Å; F410-L413 PolarHBondContact O-N 3.44Å; Y411-L413 PolarHBondContact O-N 3.12Å
414	F	85	Confident	85	Confident	11 Å²	11	58 Å²	58	5%	0.048	28%	0.279	C	S	.	.	H	α-helix	trans	-105.3	-10.8	-168.6	-55.6	-61.7	0	0	0	115.4	F281 L346 H347 A350 F410 R416	F281-F414 HydrophobicContact CD1-CZ 4.18Å; F281-F414 HydrophobicContact CD2-CE1 4.11Å; F281-F414 AromaticContact CD2-CZ 3.63Å; F281-F414 HydrophobicContact CD2-CZ 3.63Å; F281-F414 HydrophobicContact CE1-CZ 4.13Å; F281-F414 AromaticContact CE2-CE1 3.81Å; F281-F414 HydrophobicContact CE2-CE1 3.81Å; F281-F414 AromaticContact CE2-CZ 3.54Å; F281-F414 HydrophobicContact CE2-CZ 3.54Å; F281-F414 AromaticContact CG-CZ 3.95Å; F281-F414 HydrophobicContact CG-CZ 3.95Å; F281-F414 HydrophobicContact CZ-CE1 4.32Å; F281-F414 AromaticContact CZ-CZ 3.83Å; F281-F414 HydrophobicContact CZ-CZ 3.83Å; L346-F414 HydrophobicContact CB-CB 4.25Å; L346-F414 HydrophobicContact CB-CD1 3.8Å; L346-F414 HydrophobicContact CB-CD2 4.36Å; L346-F414 HydrophobicContact CB-CE1 4.25Å; L346-F414 HydrophobicContact CB-CG 3.87Å; L346-F414 HydrophobicContact CD1-CD1 3.93Å; L346-F414 HydrophobicContact CD1-CE1 3.51Å; L346-F414 HydrophobicContact CD1-CE2 4.44Å; L346-F414 HydrophobicContact CD1-CZ 3.79Å; L346-F414 HydrophobicContact CG-CD1 4.46Å; L346-F414 HydrophobicContact CG-CE1 4.43Å; H347-F414 PolarHBondContact ND1-O 3.49Å; A350-F414 HydrophobicContact CB-CB 3.85Å; F410-F414 HydrophobicContact CD1-CD2 4.09Å; F410-F414 AromaticContact CD2-CD2 3.55Å; F410-F414 HydrophobicContact CD2-CD2 3.55Å; F410-F414 AromaticContact CD2-CE2 3.46Å; F410-F414 HydrophobicContact CD2-CE2 3.46Å; F410-F414 VanDerWaalsContact CD2-CE2 3.46Å; F410-F414 HydrophobicContact CE1-CD2 4.07Å; F410-F414 AromaticContact CE2-CD2 3.52Å; F410-F414 HydrophobicContact CE2-CD2 3.52Å; F410-F414 AromaticContact CE2-CE2 3.49Å; F410-F414 HydrophobicContact CE2-CE2 3.49Å; F410-F414 VanDerWaalsContact CE2-CE2 3.49Å; F410-F414 AromaticContact CG-CD2 3.84Å; F410-F414 HydrophobicContact CG-CD2 3.84Å; F410-F414 HydrophobicContact CG-CE2 4.16Å; F410-F414 AromaticContact CZ-CD2 3.79Å; F410-F414 HydrophobicContact CZ-CD2 3.79Å; F410-F414 HydrophobicContact CZ-CE2 4.2Å; F410-F414 WeakPolarHBondContact O-CD2 3.2Å; F410-F414 PolarHBondContact O-N 3.48Å; F414-R416 PolarHBondContact O-N 2.9Å; F414-R416 VanDerWaalsContact O-N 3.16Å
415	H	82.1	Confident	85.5	Confident	71 Å²	71	56.6 Å²	56.6	33%	0.329	27%	0.271	S	S	.	.	S	Bend	trans	-61.4	-26.9	177.3	177.2	66.1	0	0	0	112.9	H347 Y411	H347-H415 PolarHBondContact CE1-O 2.95Å; H347-H415 PolarHBondContact ND1-O 3.17Å; Y411-H415 HydrophobicContact CD1-CB 3.93Å; Y411-H415 HydrophobicContact CD2-CB 4.37Å; Y411-H415 HydrophobicContact CE1-CB 3.77Å; Y411-H415 AromaticContact CE1-CD2 3.96Å; Y411-H415 AromaticContact CE1-CG 3.6Å; Y411-H415 AromaticContact CE1-ND1 3.91Å; Y411-H415 HydrophobicContact CE2-CB 4.22Å; Y411-H415 AromaticContact CE2-ND1 3.68Å; Y411-H415 HydrophobicContact CG-CB 4.26Å; Y411-H415 AromaticContact CZ-CE1 3.75Å; Y411-H415 AromaticContact CZ-CG 3.5Å; Y411-H415 AromaticContact CZ-ND1 3.29Å; Y411-H415 VanDerWaalsContact CZ-ND1 3.29Å; Y411-H415 WeakPolarHBondContact O-CA 3.38Å; Y411-H415 WeakPolarHBondContact O-CB 3.33Å; Y411-H415 PolarHBondContact O-N 3.41Å; Y411-H415 PolarHBondContact OH-CE1 3.36Å; Y411-H415 PolarHBondContact OH-ND1 3.21Å; Y411-H415 VanDerWaalsContact OH-ND1 3.1Å
416	R	82.8	Confident	86.1	Confident	171 Å²	171	57.1 Å²	57.1	65%	0.645	27%	0.27	S	S	*	.	S	Bend	trans	-109.8	109.9	168.4	-70.9	-169.3	-179.2	175.8	-0	109	F414 L418 R419	F414-R416 PolarHBondContact O-N 2.9Å; F414-R416 VanDerWaalsContact O-N 3.16Å; R416-L418 PolarHBondContact O-N 3.12Å; R416-R419 HydrophobicContact CB-CB 4.32Å; R416-R419 VanDerWaalsContact O-CB 3.29Å; R416-R419 WeakPolarHBondContact O-CB 3.33Å; R416-R419 PolarHBondContact O-N 3.46Å
417	P	75.5	Confident	86.8	Confident	23 Å²	23	58 Å²	58	15%	0.149	27%	0.272	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63.5	-29.1	-171.4	24.3	-32.2	0	0	0	112.4	H347 R419 Y476	H347-P417 HydrophobicContact CB-CB 4.11Å; P417-R419 VanDerWaalsContact C-N 3.3Å; P417-R419 PolarHBondContact O-N 3.01Å; P417-Y476 HydrophobicContact CB-CD2 4.31Å; P417-Y476 HydrophobicContact CB-CE1 4.29Å; P417-Y476 HydrophobicContact CB-CE2 3.55Å; P417-Y476 WeakPolarHBondContact CB-OH 3.29Å; P417-Y476 HydrophobicContact CG-CD1 4Å; P417-Y476 HydrophobicContact CG-CD2 3.67Å; P417-Y476 HydrophobicContact CG-CE1 3.72Å; P417-Y476 HydrophobicContact CG-CE2 3.36Å; P417-Y476 HydrophobicContact CG-CG 3.98Å
418	L	83.5	Confident	87.3	Confident	41 Å²	41	57.5 Å²	57.5	22%	0.215	27%	0.269	C	S	.	.	H	α-helix	trans	-78.1	-6.9	178.7	-59.9	175.7	0	0	0	114.2	R416 L421 N422 L472	R416-L418 PolarHBondContact O-N 3.12Å; L418-L421 HydrophobicContact CD2-CD2 4.44Å; L418-L421 PolarHBondContact O-N 2.85Å; L418-N422 VanDerWaalsContact O-CB 3.26Å; L418-N422 WeakPolarHBondContact O-CB 3.42Å; L418-N422 PolarHBondContact O-N 2.62Å; L418-N422 PolarHBondContact O-ND2 2.92Å; L418-L472 HydrophobicContact CD2-CB 3.65Å; L418-L472 HydrophobicContact CD2-CD2 4.4Å
419	R	87.1	Confident	87.8	Confident	65 Å²	65	57.1 Å²	57.1	25%	0.245	27%	0.269	C	S	.	.	H	α-helix	trans	-67.2	-47	-171.6	-170.9	-178.6	-52.7	-163.4	8.6	112.6	F412 R416 P417 L421 N422 L423	F412-R419 VanDerWaalsContact CD1-NH1 3.28Å; F412-R419 VanDerWaalsContact CG-NH1 3.32Å; F412-R419 PolarHBondContact O-NE 3.06Å; F412-R419 PolarHBondContact O-NH1 3.26Å; F412-R419 PolarHBondContact O-NH2 3.01Å; R416-R419 HydrophobicContact CB-CB 4.32Å; R416-R419 VanDerWaalsContact O-CB 3.29Å; R416-R419 WeakPolarHBondContact O-CB 3.33Å; R416-R419 PolarHBondContact O-N 3.46Å; P417-R419 VanDerWaalsContact C-N 3.3Å; P417-R419 PolarHBondContact O-N 3.01Å; R419-L421 VanDerWaalsContact C-N 3.35Å; R419-N422 PolarHBondContact O-N 3.28Å; R419-L423 PolarHBondContact O-N 3.2Å
420	L	87.6	Confident	88.3	Confident	22 Å²	22	51.6 Å²	51.6	12%	0.115	26%	0.258	C	S	.	.	H	α-helix	trans	-62.2	-46.8	177.6	-176.2	66.8	0	0	0	110	L338 N422 L423 L424	L338-L420 HydrophobicContact CD2-CD2 3.74Å; L420-N422 PolarHBondContact O-N 2.94Å; L420-L423 WeakPolarHBondContact O-CB 3.29Å; L420-L423 PolarHBondContact O-N 2.86Å; L420-L423 VanDerWaalsContact O-N 3.11Å; L420-L424 HydrophobicContact CD1-CD1 3.99Å; L420-L424 HydrophobicContact CG-CD1 3.97Å; L420-L424 WeakPolarHBondContact O-CD1 3.41Å; L420-L424 PolarHBondContact O-N 3.35Å
421	L	88.4	Confident	88.6	Confident	25 Å²	25	51.8 Å²	51.8	13%	0.131	26%	0.26	C	S	.	.	H	α-helix	trans	-60.5	-42.9	177.7	-175.6	59.9	0	0	0	112.8	L418 R419 L423 L424 I425 L465 D468 R469	L418-L421 HydrophobicContact CD2-CD2 4.44Å; L418-L421 PolarHBondContact O-N 2.85Å; R419-L421 VanDerWaalsContact C-N 3.35Å; L421-L423 VanDerWaalsContact C-N 3.3Å; L421-L423 PolarHBondContact O-N 3.3Å; L421-L424 PolarHBondContact O-N 3.21Å; L421-I425 HydrophobicContact CD1-CD1 4.46Å; L421-I425 HydrophobicContact CG-CD1 4.16Å; L421-I425 WeakPolarHBondContact O-CG1 3.3Å; L421-I425 PolarHBondContact O-N 2.82Å; L421-L465 HydrophobicContact CD1-CD2 3.82Å; L421-D468 HydrophobicContact CD2-CB 4.48Å; L421-R469 VanDerWaalsContact CD2-CA 3.44Å; L421-R469 HydrophobicContact CD2-CB 3.69Å; L421-R469 HydrophobicContact CD2-CG 4.45Å; L421-R469 HydrophobicContact CG-CB 4.16Å
422	N	91.4	Very high	89.1	Confident	67 Å²	67	51.6 Å²	51.6	36%	0.358	26%	0.261	S	S	.	.	H	α-helix	trans	-64.1	-35.4	175.5	-71.7	-18.8	0	0	0	112	L418 R419 L420 L426	L418-N422 VanDerWaalsContact O-CB 3.26Å; L418-N422 WeakPolarHBondContact O-CB 3.42Å; L418-N422 PolarHBondContact O-N 2.62Å; L418-N422 PolarHBondContact O-ND2 2.92Å; R419-N422 PolarHBondContact O-N 3.28Å; L420-N422 PolarHBondContact O-N 2.94Å; N422-L426 WeakPolarHBondContact O-CB 3.3Å; N422-L426 PolarHBondContact O-N 3.42Å
423	L	91.9	Very high	89.5	Confident	87 Å²	87	52.6 Å²	52.6	46%	0.455	27%	0.265	S	S	.	.	H	α-helix	trans	-64.7	-44.8	174.1	-179.5	68.4	0	0	0	111	R419 L420 L421 L426 I427	R419-L423 PolarHBondContact O-N 3.2Å; L420-L423 WeakPolarHBondContact O-CB 3.29Å; L420-L423 PolarHBondContact O-N 2.86Å; L420-L423 VanDerWaalsContact O-N 3.11Å; L421-L423 VanDerWaalsContact C-N 3.3Å; L421-L423 PolarHBondContact O-N 3.3Å; L423-L426 PolarHBondContact O-N 3.5Å; L423-I427 HydrophobicContact CD1-CD1 4.35Å; L423-I427 HydrophobicContact CG-CD1 4.04Å; L423-I427 VanDerWaalsContact O-CG1 3.31Å; L423-I427 WeakPolarHBondContact O-CG1 3.39Å; L423-I427 PolarHBondContact O-N 2.85Å
424	L	92	Very high	90	Very high	11 Å²	11	54.2 Å²	54.2	6%	0.058	27%	0.269	C	S	.	.	H	α-helix	trans	-62.1	-44.1	176.2	-87.2	74.9	0	0	0	111.6	T334 T335 L420 L421 L426 I427 E428 L465	T334-L424 HydrophobicContact CG2-CD1 4.1Å; T334-L424 HydrophobicContact CG2-CD2 3.79Å; T334-L424 HydrophobicContact CG2-CG 4.37Å; T335-L424 HydrophobicContact CG2-CD2 3.85Å; L420-L424 HydrophobicContact CD1-CD1 3.99Å; L420-L424 HydrophobicContact CG-CD1 3.97Å; L420-L424 WeakPolarHBondContact O-CD1 3.41Å; L420-L424 PolarHBondContact O-N 3.35Å; L421-L424 PolarHBondContact O-N 3.21Å; L424-L426 VanDerWaalsContact C-N 3.3Å; L424-L426 PolarHBondContact O-N 3.3Å; L424-I427 PolarHBondContact O-N 3.27Å; L424-E428 WeakPolarHBondContact O-CB 3.37Å; L424-E428 PolarHBondContact O-N 2.82Å; L424-L465 HydrophobicContact CB-CD1 4.4Å; L424-L465 HydrophobicContact CB-CD2 4.2Å; L424-L465 HydrophobicContact CD2-CD2 4.19Å
425	I	93.4	Very high	90.4	Very high	24 Å²	24	53.7 Å²	53.7	12%	0.123	27%	0.266	C	S	.	.	H	α-helix	trans	-61.6	-39.5	175.9	-70.3	165.9	0	0	0	111.2	L421 G429 L465 L466 R469	L421-I425 HydrophobicContact CD1-CD1 4.46Å; L421-I425 HydrophobicContact CG-CD1 4.16Å; L421-I425 WeakPolarHBondContact O-CG1 3.3Å; L421-I425 PolarHBondContact O-N 2.82Å; I425-G429 WeakPolarHBondContact O-CA 3.27Å; I425-G429 PolarHBondContact O-N 3.33Å; I425-L465 HydrophobicContact CD1-CB 4.43Å; I425-L465 HydrophobicContact CG1-CB 3.75Å; I425-L465 HydrophobicContact CG1-CD1 4.43Å; I425-L466 HydrophobicContact CG2-CD2 4.3Å; I425-R469 HydrophobicContact CD1-CB 3.53Å; I425-R469 HydrophobicContact CD1-CG 3.83Å
426	L	95	Very high	90.9	Very high	112 Å²	112	53.8 Å²	53.8	59%	0.586	27%	0.269	S	S	*	.	H	α-helix	trans	-64.8	-44.7	177.2	179.9	65.9	0	0	0	111.3	N422 L423 L424 S430	N422-L426 WeakPolarHBondContact O-CB 3.3Å; N422-L426 PolarHBondContact O-N 3.42Å; L423-L426 PolarHBondContact O-N 3.5Å; L424-L426 VanDerWaalsContact C-N 3.3Å; L424-L426 PolarHBondContact O-N 3.3Å; L426-S430 VanDerWaalsContact O-CB 3.31Å; L426-S430 WeakPolarHBondContact O-CB 3.26Å; L426-S430 PolarHBondContact O-N 2.85Å; L426-S430 PolarHBondContact O-OG 2.97Å
427	I	94.4	Very high	91.4	Very high	52 Å²	52	51.6 Å²	51.6	27%	0.267	26%	0.261	S	S	.	.	H	α-helix	trans	-62	-53.4	177.9	-68.3	166.5	0	0	0	109.9	I327 V331 L423 L424 S430 V431	I327-I427 HydrophobicContact CG2-CG2 3.42Å; I327-I427 VanDerWaalsContact CG2-CG2 3.42Å; V331-I427 HydrophobicContact CG2-CG2 4Å; L423-I427 HydrophobicContact CD1-CD1 4.35Å; L423-I427 HydrophobicContact CG-CD1 4.04Å; L423-I427 VanDerWaalsContact O-CG1 3.31Å; L423-I427 WeakPolarHBondContact O-CG1 3.39Å; L423-I427 PolarHBondContact O-N 2.85Å; L424-I427 PolarHBondContact O-N 3.27Å; I427-S430 WeakPolarHBondContact O-CB 3.4Å; I427-S430 PolarHBondContact O-N 2.89Å; I427-V431 WeakPolarHBondContact O-CG2 3.24Å; I427-V431 PolarHBondContact O-N 3.47Å; I427-V431 VanDerWaalsContact O-N 3.07Å
428	E	93.9	Very high	92.1	Very high	0 Å²	0	51 Å²	51	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-65.1	-42.9	-178.2	-172.1	58.1	-155.8	0	0	112	V331 L424 S430 V431 V432 N458 V461 L462 L465	V331-E428 HydrophobicContact CG1-CB 4.38Å; L424-E428 WeakPolarHBondContact O-CB 3.37Å; L424-E428 PolarHBondContact O-N 2.82Å; E428-S430 VanDerWaalsContact C-N 3.28Å; E428-S430 PolarHBondContact O-N 3.33Å; E428-V431 PolarHBondContact O-N 2.88Å; E428-V431 VanDerWaalsContact O-N 3.15Å; E428-V432 WeakPolarHBondContact O-CG2 3.39Å; E428-V432 PolarHBondContact O-N 3.5Å; E428-N458 WeakPolarHBondContact OE1-CB 3.47Å; E428-V461 HydrophobicContact CG-CG1 4.37Å; E428-L462 HydrophobicContact CG-CB 4.3Å; E428-L462 HydrophobicContact CG-CD1 4.35Å; E428-L465 HydrophobicContact CB-CD1 3.99Å; E428-L465 HydrophobicContact CG-CD1 4.23Å
429	G	94.6	Very high	92.5	Very high	28 Å²	28	51.1 Å²	51.1	29%	0.289	26%	0.258	S	S	.	.	H	α-helix	trans	-61.2	-36.6	175.5	0	0	0	0	0	112.6	I425 F433	I425-G429 WeakPolarHBondContact O-CA 3.27Å; I425-G429 PolarHBondContact O-N 3.33Å; G429-F433 VanDerWaalsContact O-CB 3.27Å; G429-F433 WeakPolarHBondContact O-CB 3.26Å; G429-F433 PolarHBondContact O-N 3.39Å
430	S	94.8	Very high	92.6	Very high	68 Å²	68	54.9 Å²	54.9	48%	0.476	28%	0.283	S	S	.	.	H	α-helix	trans	-67	-39.7	174.8	-58.3	0	0	0	0	111.8	L426 I427 E428 Y434	L426-S430 VanDerWaalsContact O-CB 3.31Å; L426-S430 WeakPolarHBondContact O-CB 3.26Å; L426-S430 PolarHBondContact O-N 2.85Å; L426-S430 PolarHBondContact O-OG 2.97Å; I427-S430 WeakPolarHBondContact O-CB 3.4Å; I427-S430 PolarHBondContact O-N 2.89Å; E428-S430 VanDerWaalsContact C-N 3.28Å; E428-S430 PolarHBondContact O-N 3.33Å; S430-Y434 WeakPolarHBondContact O-CB 3.48Å; S430-Y434 PolarHBondContact O-N 3.47Å
431	V	94	Very high	92.8	Very high	12 Å²	12	62.6 Å²	62.6	7%	0.073	31%	0.31	C	S	.	.	H	α-helix	trans	-64.8	-48.9	175.7	172.5	0	0	0	0	111.1	I327 I427 E428 F433 Y434 Q435	I327-V431 HydrophobicContact CB-CG2 4.2Å; I327-V431 HydrophobicContact CD1-CG2 4.28Å; I327-V431 HydrophobicContact CG2-CG2 3.59Å; I427-V431 WeakPolarHBondContact O-CG2 3.24Å; I427-V431 PolarHBondContact O-N 3.47Å; I427-V431 VanDerWaalsContact O-N 3.07Å; E428-V431 PolarHBondContact O-N 2.88Å; E428-V431 VanDerWaalsContact O-N 3.15Å; V431-F433 VanDerWaalsContact C-N 3.33Å; V431-F433 PolarHBondContact O-N 3.37Å; V431-Y434 PolarHBondContact O-N 2.89Å; V431-Q435 HydrophobicContact CG1-CG 4.39Å; V431-Q435 WeakPolarHBondContact O-CB 3.5Å; V431-Q435 VanDerWaalsContact O-CG 3.3Å; V431-Q435 WeakPolarHBondContact O-CG 3.47Å; V431-Q435 PolarHBondContact O-N 2.94Å
432	V	94.8	Very high	92.8	Very high	15 Å²	15	62.5 Å²	62.5	9%	0.091	31%	0.312	C	S	.	.	H	α-helix	trans	-61.4	-41.6	178.3	169.4	0	0	0	0	111.2	E428 Q435 L436 L455 N458 Y459 L462	E428-V432 WeakPolarHBondContact O-CG2 3.39Å; E428-V432 PolarHBondContact O-N 3.5Å; V432-Q435 PolarHBondContact O-N 3.1Å; V432-L436 WeakPolarHBondContact O-CB 3.47Å; V432-L436 PolarHBondContact O-N 3.41Å; V432-L455 HydrophobicContact CG1-CD1 3.88Å; V432-N458 HydrophobicContact CG2-CB 3.91Å; V432-Y459 HydrophobicContact CG1-CD1 4.48Å; V432-Y459 HydrophobicContact CG1-CE1 3.96Å; V432-L462 HydrophobicContact CG1-CD2 4.33Å; V432-L462 HydrophobicContact CG2-CD2 4.35Å
433	F	94.7	Very high	92.5	Very high	148 Å²	148	68.6 Å²	68.6	65%	0.649	34%	0.338	S	S	*	.	H	α-helix	trans	-63.5	-44.1	175.8	-175.9	-97.6	0	0	0	111.9	G429 V431 L436 Y437	G429-F433 VanDerWaalsContact O-CB 3.27Å; G429-F433 WeakPolarHBondContact O-CB 3.26Å; G429-F433 PolarHBondContact O-N 3.39Å; V431-F433 VanDerWaalsContact C-N 3.33Å; V431-F433 PolarHBondContact O-N 3.37Å; F433-L436 PolarHBondContact O-N 2.99Å; F433-Y437 WeakPolarHBondContact O-CB 3.43Å; F433-Y437 PolarHBondContact O-N 3.49Å
434	Y	92.9	Very high	92.2	Very high	86 Å²	86	69.2 Å²	69.2	34%	0.337	34%	0.337	S	S	.	.	H	α-helix	trans	-61.7	-43.1	175.2	172.9	-97.5	0	0	0	112.1	E320 M324 S430 V431 Y437 S438	E320-Y434 PolarHBondContact OE1-OH 3.49Å; E320-Y434 PolarHBondContact OE2-OH 3.35Å; M324-Y434 HydrophobicContact SD-CD1 4.23Å; M324-Y434 HydrophobicContact SD-CE1 4.06Å; S430-Y434 WeakPolarHBondContact O-CB 3.48Å; S430-Y434 PolarHBondContact O-N 3.47Å; V431-Y434 PolarHBondContact O-N 2.89Å; Y434-Y437 PolarHBondContact O-N 2.9Å; Y434-S438 VanDerWaalsContact O-CB 3.29Å; Y434-S438 WeakPolarHBondContact O-CB 3.24Å; Y434-S438 PolarHBondContact O-N 2.79Å
435	Q	92.9	Very high	91.9	Very high	0 Å²	0	72.3 Å²	72.3	0%	0	35%	0.348	C	S	.	.	H	α-helix	trans	-62.6	-42.4	176.8	-74.8	170.8	-18.3	0	0	112	M324 V431 V432 S438 L439 M451 L455 N458	M324-Q435 HydrophobicContact SD-CG 3.74Å; V431-Q435 HydrophobicContact CG1-CG 4.39Å; V431-Q435 WeakPolarHBondContact O-CB 3.5Å; V431-Q435 VanDerWaalsContact O-CG 3.3Å; V431-Q435 WeakPolarHBondContact O-CG 3.47Å; V431-Q435 PolarHBondContact O-N 2.94Å; V432-Q435 PolarHBondContact O-N 3.1Å; Q435-S438 PolarHBondContact O-N 2.91Å; Q435-L439 VanDerWaalsContact O-CB 3.24Å; Q435-L439 WeakPolarHBondContact O-CB 3.42Å; Q435-L439 PolarHBondContact O-N 3.48Å; Q435-M451 HydrophobicContact CB-SD 4.36Å; Q435-M451 HydrophobicContact CG-SD 4.07Å; Q435-L455 HydrophobicContact CB-CD1 4.01Å; Q435-N458 VanDerWaalsContact CD-ND2 3.31Å; Q435-N458 PolarHBondContact NE2-ND2 3.22Å; Q435-N458 PolarHBondContact OE1-ND2 2.98Å
436	L	93.3	Very high	91.4	Very high	73 Å²	73	71.3 Å²	71.3	38%	0.382	34%	0.343	S	S	.	.	H	α-helix	trans	-64.3	-45	176.1	-173.1	68.4	0	0	0	111.3	V432 F433 L439 L440	V432-L436 WeakPolarHBondContact O-CB 3.47Å; V432-L436 PolarHBondContact O-N 3.41Å; F433-L436 PolarHBondContact O-N 2.99Å; L436-L439 PolarHBondContact O-N 2.81Å; L436-L440 WeakPolarHBondContact O-CG 3.32Å; L436-L440 PolarHBondContact O-N 3.43Å
437	Y	93.1	Very high	91.1	Very high	124 Å²	124	66.8 Å²	66.8	49%	0.486	32%	0.319	S	S	.	.	H	α-helix	trans	-60.8	-44.9	175.1	172	-103.2	0	0	0	111.9	F433 Y434 L439 L440 R441	F433-Y437 WeakPolarHBondContact O-CB 3.43Å; F433-Y437 PolarHBondContact O-N 3.49Å; Y434-Y437 PolarHBondContact O-N 2.9Å; Y437-L439 VanDerWaalsContact C-N 3.35Å; Y437-L440 PolarHBondContact O-N 3.44Å; Y437-R441 PolarHBondContact O-N 3.11Å
438	S	90	Very high	90.9	Very high	12 Å²	12	66.8 Å²	66.8	8%	0.084	32%	0.321	C	S	.	.	H	α-helix	trans	-64.8	-39.7	178.3	-166.2	0	0	0	0	111.5	W317 Y434 Q435 R441 S442	W317-S438 WeakPolarHBondContact CH2-OG 3.25Å; Y434-S438 VanDerWaalsContact O-CB 3.29Å; Y434-S438 WeakPolarHBondContact O-CB 3.24Å; Y434-S438 PolarHBondContact O-N 2.79Å; Q435-S438 PolarHBondContact O-N 2.91Å; S438-R441 PolarHBondContact O-N 3.35Å; S438-S442 WeakPolarHBondContact O-CB 3.23Å; S438-S442 PolarHBondContact O-N 3.37Å; S438-S442 VanDerWaalsContact O-N 3.09Å
439	L	91.7	Very high	90.6	Very high	42 Å²	42	70.1 Å²	70.1	22%	0.22	34%	0.339	C	S	.	.	H	α-helix	trans	-60.7	-44.8	175.4	-175.8	68.9	0	0	0	111.8	Q435 L436 Y437 R441 S442 T448 M451 L455	Q435-L439 VanDerWaalsContact O-CB 3.24Å; Q435-L439 WeakPolarHBondContact O-CB 3.42Å; Q435-L439 PolarHBondContact O-N 3.48Å; L436-L439 PolarHBondContact O-N 2.81Å; Y437-L439 VanDerWaalsContact C-N 3.35Å; L439-R441 VanDerWaalsContact C-N 3.27Å; L439-R441 PolarHBondContact O-N 2.82Å; L439-S442 WeakPolarHBondContact O-CB 3.32Å; L439-S442 PolarHBondContact O-N 3.42Å; L439-T448 HydrophobicContact CD1-CG2 3.69Å; L439-T448 WeakPolarHBondContact CD1-O 3.25Å; L439-M451 HydrophobicContact CB-CB 4.32Å; L439-M451 HydrophobicContact CD1-CB 3.93Å; L439-L455 HydrophobicContact CD2-CD2 4.22Å
440	L	90.6	Very high	90.3	Very high	144 Å²	144	69 Å²	69	75%	0.754	33%	0.326	S	S	*	.	H	α-helix	trans	-64.6	-30.5	178	-70.6	171.4	0	0	0	113.1	L436 Y437	L436-L440 WeakPolarHBondContact O-CG 3.32Å; L436-L440 PolarHBondContact O-N 3.43Å; Y437-L440 PolarHBondContact O-N 3.44Å
441	R	91.4	Very high	90.1	Very high	185 Å²	185	65.8 Å²	65.8	70%	0.698	30%	0.304	S	S	*	.	H	α-helix	trans	-87	-7.6	178.2	-169.5	174.7	170.8	-179.9	-0.7	113	Y437 S438 L439 E443	Y437-R441 PolarHBondContact O-N 3.11Å; S438-R441 PolarHBondContact O-N 3.35Å; L439-R441 VanDerWaalsContact C-N 3.27Å; L439-R441 PolarHBondContact O-N 2.82Å; R441-E443 PolarHBondContact O-N 2.98Å
442	S	88.5	Confident	89.9	Confident	23 Å²	23	67.3 Å²	67.3	16%	0.161	32%	0.318	C	S	.	.			trans	-81.9	111.9	-168.2	-164.2	0	0	0	0	112.6	S438 L439 H447 T448	S438-S442 WeakPolarHBondContact O-CB 3.23Å; S438-S442 PolarHBondContact O-N 3.37Å; S438-S442 VanDerWaalsContact O-N 3.09Å; L439-S442 WeakPolarHBondContact O-CB 3.32Å; L439-S442 PolarHBondContact O-N 3.42Å; S442-H447 WeakPolarHBondContact OG-CB 3.3Å; S442-T448 PolarHBondContact OG-N 3.37Å
443	E	84.3	Confident	89.7	Confident	195 Å²	195	69.4 Å²	69.4	91%	0.911	33%	0.328	S	S	*	.			trans	-89.2	-21	177.6	-63.2	176.6	-178.5	0	0	113	R441	R441-E443 PolarHBondContact O-N 2.98Å
444	K	85.6	Confident	89.5	Confident	100 Å²	100	62.4 Å²	62.4	44%	0.435	30%	0.298	S	S	.	.	S	Bend	trans	-94.9	130.1	-175.6	-58.6	178.1	-172.2	166.8	0	110.6	D314 N446 H447 T448	D314-K444 IonicContact OD2-NZ 3.32Å; K444-N446 WeakPolarHBondContact CB-OD1 3.46Å; K444-N446 PolarHBondContact O-N 2.67Å; K444-N446 VanDerWaalsContact O-N 3.1Å; K444-H447 HydrophobicContact CB-CB 4.33Å; K444-H447 WeakPolarHBondContact O-CB 3.32Å; K444-H447 PolarHBondContact O-N 3.32Å; K444-T448 PolarHBondContact O-N 3.33Å; K444-T448 PolarHBondContact O-OG1 3.18Å; K444-T448 VanDerWaalsContact O-OG1 3.13Å
445	W	85.9	Confident	89.5	Confident	75 Å²	75	58.7 Å²	58.7	28%	0.284	28%	0.284	S	S	.	.	H	α-helix	trans	-51.9	-39.6	-179	77.4	-85.2	0	0	0	113.8	I92 K96 W100 H447 T448 L449	I92-W445 HydrophobicContact CG2-CH2 4.07Å; I92-W445 HydrophobicContact CG2-CZ3 4.24Å; K96-W445 HydrophobicContact CB-CZ2 4.12Å; W100-W445 AromaticContact CH2-CD1 3.02Å; W100-W445 HydrophobicContact CH2-CG 4.06Å; W100-W445 AromaticContact CH2-NE1 3.03Å; W100-W445 AromaticContact CZ2-CD1 3.94Å; W100-W445 AromaticContact CZ3-CD1 3.38Å; W100-W445 HydrophobicContact CZ3-CD2 4.32Å; W100-W445 AromaticContact CZ3-CE2 3.79Å; W100-W445 HydrophobicContact CZ3-CG 4.07Å; W100-W445 HydrophobicContact CZ3-CZ2 4.48Å; W100-W445 AromaticContact CZ3-NE1 3.18Å; W445-H447 VanDerWaalsContact C-N 3.34Å; W445-T448 PolarHBondContact O-N 3.05Å; W445-L449 HydrophobicContact CE3-CD2 4.3Å; W445-L449 HydrophobicContact CZ3-CD2 3.87Å; W445-L449 WeakPolarHBondContact O-CB 3.09Å; W445-L449 PolarHBondContact O-N 3.23Å
446	N	84.1	Confident	89.3	Confident	4 Å²	4	66.1 Å²	66.1	2%	0.021	32%	0.316	C	S	.	.	H	α-helix	trans	-68.7	-37.9	-177.2	67.5	-62	0	0	0	110.7	I92 K96 K444 S450	I92-N446 HydrophobicContact CG2-CB 4.22Å; K96-N446 HydrophobicContact CD-CB 4.3Å; K96-N446 WeakPolarHBondContact CD-ND2 3.46Å; K96-N446 PolarHBondContact NZ-ND2 2.88Å; K444-N446 WeakPolarHBondContact CB-OD1 3.46Å; K444-N446 PolarHBondContact O-N 2.67Å; K444-N446 VanDerWaalsContact O-N 3.1Å; N446-S450 VanDerWaalsContact O-CB 3.25Å; N446-S450 WeakPolarHBondContact O-CB 3.49Å; N446-S450 PolarHBondContact O-N 3.23Å; N446-S450 PolarHBondContact O-OG 2.8Å
447	H	88	Confident	89.1	Confident	16 Å²	16	63.9 Å²	63.9	7%	0.074	31%	0.306	C	S	.	.	H	α-helix	trans	-68.3	-43.4	176	-67.3	-174.7	0	0	0	110.3	D314 W317 S442 K444 W445 S450 M451	D314-H447 IonicContact OD2-CE1 2.9Å; W317-H447 AromaticContact CD1-CD2 3.66Å; W317-H447 AromaticContact CD1-NE2 3.86Å; W317-H447 HydrophobicContact CD2-CB 4.45Å; W317-H447 AromaticContact CD2-CD2 3.65Å; W317-H447 AromaticContact CD2-CE1 3.83Å; W317-H447 AromaticContact CD2-CG 3.78Å; W317-H447 AromaticContact CD2-ND1 3.88Å; W317-H447 AromaticContact CD2-NE2 3.8Å; W317-H447 AromaticContact CE2-CD2 3.47Å; W317-H447 VanDerWaalsContact CE2-CD2 3.47Å; W317-H447 AromaticContact CE2-CG 3.54Å; W317-H447 AromaticContact CE3-CE1 3.97Å; W317-H447 AromaticContact CE3-ND1 3.83Å; W317-H447 AromaticContact CG-CD2 3.75Å; W317-H447 AromaticContact CG-CE1 4Å; W317-H447 AromaticContact CG-NE2 3.61Å; W317-H447 HydrophobicContact CH2-CB 3.67Å; W317-H447 AromaticContact CH2-CG 3.93Å; W317-H447 VanDerWaalsContact CZ2-CA 3.47Å; W317-H447 HydrophobicContact CZ2-CB 3.38Å; W317-H447 AromaticContact CZ2-CG 3.63Å; W317-H447 HydrophobicContact CZ3-CB 4.34Å; W317-H447 AromaticContact CZ3-ND1 3.98Å; W317-H447 AromaticContact NE1-CD2 3.47Å; W317-H447 PolarHBondContact NE1-CD2 3.37Å; S442-H447 WeakPolarHBondContact OG-CB 3.3Å; K444-H447 HydrophobicContact CB-CB 4.33Å; K444-H447 WeakPolarHBondContact O-CB 3.32Å; K444-H447 PolarHBondContact O-N 3.32Å; W445-H447 VanDerWaalsContact C-N 3.34Å; H447-S450 WeakPolarHBondContact CA-OG 3.44Å; H447-S450 PolarHBondContact O-N 3.04Å; H447-S450 PolarHBondContact O-OG 3.14Å; H447-M451 WeakPolarHBondContact O-CB 3.42Å; H447-M451 WeakPolarHBondContact O-CG 3.32Å; H447-M451 PolarHBondContact O-N 3.06Å
448	T	89.2	Confident	89	Confident	53 Å²	53	58 Å²	58	33%	0.325	28%	0.283	S	S	.	.	H	α-helix	trans	-60.8	-48.1	176.2	-44.9	0	0	0	0	111.8	L439 S442 K444 W445 M451 A452	L439-T448 HydrophobicContact CD1-CG2 3.69Å; L439-T448 WeakPolarHBondContact CD1-O 3.25Å; S442-T448 PolarHBondContact OG-N 3.37Å; K444-T448 PolarHBondContact O-N 3.33Å; K444-T448 PolarHBondContact O-OG1 3.18Å; K444-T448 VanDerWaalsContact O-OG1 3.13Å; W445-T448 PolarHBondContact O-N 3.05Å; T448-M451 PolarHBondContact O-N 3.22Å; T448-A452 WeakPolarHBondContact O-CB 3.11Å; T448-A452 PolarHBondContact O-N 2.94Å
449	L	89.1	Confident	89	Confident	70 Å²	70	62.6 Å²	62.6	37%	0.366	30%	0.299	S	S	.	.	H	α-helix	trans	-64.7	-45	179.8	-176.5	66.5	0	0	0	111.8	I92 W445 M451 A452 L453	I92-L449 HydrophobicContact CD1-CD2 4.07Å; W445-L449 HydrophobicContact CE3-CD2 4.3Å; W445-L449 HydrophobicContact CZ3-CD2 3.87Å; W445-L449 WeakPolarHBondContact O-CB 3.09Å; W445-L449 PolarHBondContact O-N 3.23Å; L449-M451 PolarHBondContact O-N 3.25Å; L449-A452 PolarHBondContact O-N 2.75Å; L449-L453 HydrophobicContact CD1-CD1 4.25Å; L449-L453 HydrophobicContact CD1-CG 4.41Å; L449-L453 HydrophobicContact CG-CD1 4.18Å; L449-L453 WeakPolarHBondContact O-CG 3.05Å; L449-L453 PolarHBondContact O-N 3.2Å; L449-L453 VanDerWaalsContact O-N 3.12Å
450	S	88.4	Confident	88.8	Confident	3 Å²	3	65 Å²	65	2%	0.021	31%	0.306	C	S	.	.	H	α-helix	trans	-60	-45.9	178.3	62.8	0	0	0	0	112.1	W317 N446 H447 I454	W317-S450 WeakPolarHBondContact CZ2-OG 3.3Å; W317-S450 PolarHBondContact NE1-OG 3.13Å; N446-S450 VanDerWaalsContact O-CB 3.25Å; N446-S450 WeakPolarHBondContact O-CB 3.49Å; N446-S450 PolarHBondContact O-N 3.23Å; N446-S450 PolarHBondContact O-OG 2.8Å; H447-S450 WeakPolarHBondContact CA-OG 3.44Å; H447-S450 PolarHBondContact O-N 3.04Å; H447-S450 PolarHBondContact O-OG 3.14Å; S450-I454 WeakPolarHBondContact O-CG1 3.27Å; S450-I454 PolarHBondContact O-N 3.43Å
451	M	89.8	Confident	88.8	Confident	1 Å²	1	58.6 Å²	58.6	1%	0.005	27%	0.273	C	S	.	.	H	α-helix	trans	-67.3	-42	178.4	-73	-65.9	178.7	0	0	112.1	W317 M324 Q435 L439 H447 T448 L449 L453 I454 L455	W317-M451 HydrophobicContact CH2-CE 3.21Å; W317-M451 HydrophobicContact CH2-CG 3.72Å; W317-M451 HydrophobicContact CH2-SD 4.33Å; W317-M451 HydrophobicContact CZ2-CE 3.44Å; W317-M451 VanDerWaalsContact CZ2-CE 3.44Å; W317-M451 HydrophobicContact CZ2-CG 3.65Å; W317-M451 HydrophobicContact CZ2-SD 4.34Å; W317-M451 HydrophobicContact CZ3-CE 3.83Å; M324-M451 HydrophobicContact CE-CE 3.44Å; M324-M451 VanDerWaalsContact CE-CE 3.44Å; M324-M451 HydrophobicContact CE-SD 3.94Å; M324-M451 HydrophobicContact SD-CE 3.81Å; M324-M451 HydrophobicContact SD-SD 3.96Å; Q435-M451 HydrophobicContact CB-SD 4.36Å; Q435-M451 HydrophobicContact CG-SD 4.07Å; L439-M451 HydrophobicContact CB-CB 4.32Å; L439-M451 HydrophobicContact CD1-CB 3.93Å; H447-M451 WeakPolarHBondContact O-CB 3.42Å; H447-M451 WeakPolarHBondContact O-CG 3.32Å; H447-M451 PolarHBondContact O-N 3.06Å; T448-M451 PolarHBondContact O-N 3.22Å; L449-M451 PolarHBondContact O-N 3.25Å; M451-L453 PolarHBondContact O-N 3.43Å; M451-I454 PolarHBondContact O-N 3.1Å; M451-L455 WeakPolarHBondContact O-CB 3.46Å; M451-L455 PolarHBondContact O-N 3.2Å
452	A	90.7	Very high	88.8	Confident	45 Å²	45	51.3 Å²	51.3	37%	0.372	25%	0.247	S	C	.	.	H	α-helix	trans	-61.2	-42.9	-179.9	0	0	0	0	0	112.7	T448 L449 F456	T448-A452 WeakPolarHBondContact O-CB 3.11Å; T448-A452 PolarHBondContact O-N 2.94Å; L449-A452 PolarHBondContact O-N 2.75Å; A452-F456 PolarHBondContact O-N 3.49Å
453	L	90.4	Very high	88.9	Confident	58 Å²	58	56.5 Å²	56.5	30%	0.304	27%	0.268	S	S	.	.	H	α-helix	trans	-68.6	-42.9	-179.9	-71.8	173.8	0	0	0	112.6	V85 I89 L449 M451 F456 C457	V85-L453 HydrophobicContact CG1-CB 4.17Å; I89-L453 HydrophobicContact CD1-CB 3.56Å; I89-L453 HydrophobicContact CD1-CD1 4.2Å; I89-L453 HydrophobicContact CG1-CB 4.33Å; I89-L453 HydrophobicContact CG1-CD1 4.06Å; L449-L453 HydrophobicContact CD1-CD1 4.25Å; L449-L453 HydrophobicContact CD1-CG 4.41Å; L449-L453 HydrophobicContact CG-CD1 4.18Å; L449-L453 WeakPolarHBondContact O-CG 3.05Å; L449-L453 PolarHBondContact O-N 3.2Å; L449-L453 VanDerWaalsContact O-N 3.12Å; M451-L453 PolarHBondContact O-N 3.43Å; L453-F456 PolarHBondContact O-N 3.24Å; L453-C457 PolarHBondContact O-N 3Å
454	I	90.3	Very high	89	Confident	2 Å²	2	48.4 Å²	48.4	1%	0.01	23%	0.229	C	C	.	.	H	α-helix	trans	-67.2	-42.8	176.9	-60.4	166.4	0	0	0	110.2	I89 H321 M324 S450 M451 F456 C457 N458	I89-I454 HydrophobicContact CD1-CD1 4.11Å; I89-I454 HydrophobicContact CD1-CG1 3.45Å; I89-I454 VanDerWaalsContact CD1-CG1 3.45Å; I89-I454 HydrophobicContact CG2-CD1 4.3Å; H321-I454 VanDerWaalsContact CE1-CD1 3.4Å; H321-I454 WeakPolarHBondContact CE1-CD1 3.4Å; H321-I454 WeakPolarHBondContact ND1-CD1 3.27Å; M324-I454 HydrophobicContact CE-CD1 4.4Å; S450-I454 WeakPolarHBondContact O-CG1 3.27Å; S450-I454 PolarHBondContact O-N 3.43Å; M451-I454 PolarHBondContact O-N 3.1Å; I454-F456 VanDerWaalsContact C-N 3.26Å; I454-F456 PolarHBondContact O-N 2.92Å; I454-C457 WeakPolarHBondContact O-CB 3.24Å; I454-C457 PolarHBondContact O-N 3.36Å; I454-C457 VanDerWaalsContact O-N 3.1Å; I454-N458 PolarHBondContact O-N 3.38Å; I454-N458 PolarHBondContact O-OD1 2.99Å
455	L	91.4	Very high	89.2	Confident	8 Å²	8	43.7 Å²	43.7	4%	0.042	21%	0.209	C	C	.	.	H	α-helix	trans	-59.2	-39.6	179.3	-176	64.6	0	0	0	111.4	V432 Q435 L439 M451 C457 N458 Y459	V432-L455 HydrophobicContact CG1-CD1 3.88Å; Q435-L455 HydrophobicContact CB-CD1 4.01Å; L439-L455 HydrophobicContact CD2-CD2 4.22Å; M451-L455 WeakPolarHBondContact O-CB 3.46Å; M451-L455 PolarHBondContact O-N 3.2Å; L455-C457 PolarHBondContact O-N 3.3Å; L455-N458 PolarHBondContact O-N 2.89Å; L455-Y459 HydrophobicContact CD1-CE1 3.92Å; L455-Y459 HydrophobicContact CD1-CE2 4.44Å; L455-Y459 HydrophobicContact CD2-CE2 4.27Å; L455-Y459 WeakPolarHBondContact CD2-OH 3.1Å; L455-Y459 HydrophobicContact CG-CE1 4.16Å; L455-Y459 HydrophobicContact CG-CE2 3.79Å; L455-Y459 WeakPolarHBondContact O-CD2 3.28Å; L455-Y459 PolarHBondContact O-N 2.81Å
456	F	90.3	Very high	89.4	Confident	156 Å²	156	43.2 Å²	43.2	68%	0.684	21%	0.212	S	C	*	.	H	α-helix	trans	-59.2	-45.3	174	179.6	-99.7	0	0	0	112.4	A452 L453 I454 N458 Y459	A452-F456 PolarHBondContact O-N 3.49Å; L453-F456 PolarHBondContact O-N 3.24Å; I454-F456 VanDerWaalsContact C-N 3.26Å; I454-F456 PolarHBondContact O-N 2.92Å; F456-N458 VanDerWaalsContact C-N 3.34Å; F456-N458 PolarHBondContact O-N 3.45Å; F456-Y459 PolarHBondContact O-N 2.89Å
457	C	87.9	Confident	89.7	Confident	25 Å²	25	46.2 Å²	46.2	17%	0.169	22%	0.223	C	C	.	.	H	α-helix	trans	-63.3	-40.2	175.3	-65.5	0	0	0	0	112.1	Y82 L453 I454 L455 Y459 Y460	Y82-C457 HydrophobicContact CD2-CB 3.83Å; Y82-C457 HydrophobicContact CE2-CB 4.49Å; L453-C457 PolarHBondContact O-N 3Å; I454-C457 WeakPolarHBondContact O-CB 3.24Å; I454-C457 PolarHBondContact O-N 3.36Å; I454-C457 VanDerWaalsContact O-N 3.1Å; L455-C457 PolarHBondContact O-N 3.3Å; C457-Y459 VanDerWaalsContact C-N 3.33Å; C457-Y459 PolarHBondContact O-N 3.48Å; C457-Y460 PolarHBondContact O-N 3.5Å
458	N	91	Very high	89.6	Confident	0 Å²	0	46.6 Å²	46.6	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-68.4	-29.9	-178	-72.2	8.9	0	0	0	112.8	N328 E428 V432 Q435 I454 L455 F456 Y460 V461 L462	N328-N458 PolarHBondContact ND2-OD1 3Å; E428-N458 WeakPolarHBondContact OE1-CB 3.47Å; V432-N458 HydrophobicContact CG2-CB 3.91Å; Q435-N458 VanDerWaalsContact CD-ND2 3.31Å; Q435-N458 PolarHBondContact NE2-ND2 3.22Å; Q435-N458 PolarHBondContact OE1-ND2 2.98Å; I454-N458 PolarHBondContact O-N 3.38Å; I454-N458 PolarHBondContact O-OD1 2.99Å; L455-N458 PolarHBondContact O-N 2.89Å; F456-N458 VanDerWaalsContact C-N 3.34Å; F456-N458 PolarHBondContact O-N 3.45Å; N458-Y460 VanDerWaalsContact C-N 3.28Å; N458-Y460 PolarHBondContact O-N 3.26Å; N458-V461 PolarHBondContact O-N 2.76Å; N458-L462 WeakPolarHBondContact O-CB 3.46Å; N458-L462 PolarHBondContact O-N 2.82Å
459	Y	90.5	Very high	89.6	Confident	109 Å²	109	49.4 Å²	49.4	43%	0.427	23%	0.23	S	C	.	.	H	α-helix	trans	-61	-36.6	175.8	-72.1	-37.7	0	0	0	113.4	V432 L455 F456 C457 F463	V432-Y459 HydrophobicContact CG1-CD1 4.48Å; V432-Y459 HydrophobicContact CG1-CE1 3.96Å; L455-Y459 HydrophobicContact CD1-CE1 3.92Å; L455-Y459 HydrophobicContact CD1-CE2 4.44Å; L455-Y459 HydrophobicContact CD2-CE2 4.27Å; L455-Y459 WeakPolarHBondContact CD2-OH 3.1Å; L455-Y459 HydrophobicContact CG-CE1 4.16Å; L455-Y459 HydrophobicContact CG-CE2 3.79Å; L455-Y459 WeakPolarHBondContact O-CD2 3.28Å; L455-Y459 PolarHBondContact O-N 2.81Å; F456-Y459 PolarHBondContact O-N 2.89Å; C457-Y459 VanDerWaalsContact C-N 3.33Å; C457-Y459 PolarHBondContact O-N 3.48Å; Y459-F463 VanDerWaalsContact O-CB 3.25Å; Y459-F463 WeakPolarHBondContact O-CB 3.48Å; Y459-F463 PolarHBondContact O-N 2.86Å
460	Y	88.1	Confident	89.5	Confident	94 Å²	94	50.2 Å²	50.2	37%	0.369	23%	0.234	S	C	.	.	H	α-helix	trans	-62	-45.7	175.1	175.7	-100.9	0	0	0	111.4	D70 L78 C457 N458 F463 K464	D70-Y460 PolarHBondContact OD2-OH 3.41Å; L78-Y460 HydrophobicContact CD1-CE1 3.65Å; C457-Y460 PolarHBondContact O-N 3.5Å; N458-Y460 VanDerWaalsContact C-N 3.28Å; N458-Y460 PolarHBondContact O-N 3.26Å; Y460-F463 PolarHBondContact O-N 2.92Å; Y460-K464 WeakPolarHBondContact O-CB 3.36Å; Y460-K464 PolarHBondContact O-N 3.43Å
461	V	88.9	Confident	89.4	Confident	8 Å²	8	52.4 Å²	52.4	5%	0.048	25%	0.247	C	C	.	.	H	α-helix	trans	-64.2	-46.8	179.7	-177.9	0	0	0	0	110.8	V331 M332 E428 N458 F463 K464 L465	V331-V461 HydrophobicContact CG1-CG1 3.79Å; M332-V461 HydrophobicContact CE-CG2 4.46Å; M332-V461 HydrophobicContact CG-CG1 4.33Å; M332-V461 HydrophobicContact CG-CG2 3.66Å; M332-V461 HydrophobicContact SD-CG2 4.06Å; E428-V461 HydrophobicContact CG-CG1 4.37Å; N458-V461 PolarHBondContact O-N 2.76Å; V461-F463 PolarHBondContact O-N 3.42Å; V461-K464 PolarHBondContact O-N 3.3Å; V461-L465 HydrophobicContact CG1-CD1 4.25Å; V461-L465 WeakPolarHBondContact O-CG 3.24Å; V461-L465 PolarHBondContact O-N 2.99Å
462	L	91.8	Very high	89.1	Confident	32 Å²	32	52.7 Å²	52.7	17%	0.168	25%	0.248	C	C	.	.	H	α-helix	trans	-61.3	-45.5	177.8	-177.9	63.3	0	0	0	111.8	E428 V432 N458 K464 L465 L466	E428-L462 HydrophobicContact CG-CB 4.3Å; E428-L462 HydrophobicContact CG-CD1 4.35Å; V432-L462 HydrophobicContact CG1-CD2 4.33Å; V432-L462 HydrophobicContact CG2-CD2 4.35Å; N458-L462 WeakPolarHBondContact O-CB 3.46Å; N458-L462 PolarHBondContact O-N 2.82Å; L462-K464 VanDerWaalsContact C-N 3.34Å; L462-K464 PolarHBondContact O-N 2.9Å; L462-L465 PolarHBondContact O-N 3.43Å; L462-L466 HydrophobicContact CD1-CD1 4.22Å; L462-L466 HydrophobicContact CD1-CG 4.32Å; L462-L466 HydrophobicContact CG-CD1 3.99Å; L462-L466 HydrophobicContact CG-CG 4.49Å; L462-L466 WeakPolarHBondContact O-CB 3.26Å; L462-L466 VanDerWaalsContact O-CG 3.32Å; L462-L466 WeakPolarHBondContact O-CG 3.16Å; L462-L466 PolarHBondContact O-N 2.74Å
463	F	90.8	Very high	88.8	Confident	133 Å²	133	51.2 Å²	51.2	58%	0.583	24%	0.237	S	C	*	.	H	α-helix	trans	-58.3	-46.7	176	170.4	-102.1	0	0	0	111.4	Y459 Y460 V461 L465 L466 R467	Y459-F463 VanDerWaalsContact O-CB 3.25Å; Y459-F463 WeakPolarHBondContact O-CB 3.48Å; Y459-F463 PolarHBondContact O-N 2.86Å; Y460-F463 PolarHBondContact O-N 2.92Å; V461-F463 PolarHBondContact O-N 3.42Å; F463-L465 PolarHBondContact O-N 2.64Å; F463-L466 PolarHBondContact O-N 2.73Å; F463-R467 WeakPolarHBondContact O-CB 3.43Å; F463-R467 PolarHBondContact O-N 3.28Å
464	K	87.3	Confident	88.4	Confident	24 Å²	24	56.5 Å²	56.5	10%	0.104	25%	0.253	C	S	.	.	H	α-helix	trans	-59.8	-47.6	178.3	-175.5	178.1	174.4	179.8	0	111.7	D70 Y460 V461 L462 L466 R467 D468	D70-K464 WeakPolarHBondContact OD2-CE 2.77Å; D70-K464 IonicContact OD2-NZ 3.23Å; D70-K464 PolarHBondContact OD2-NZ 3.33Å; Y460-K464 WeakPolarHBondContact O-CB 3.36Å; Y460-K464 PolarHBondContact O-N 3.43Å; V461-K464 PolarHBondContact O-N 3.3Å; L462-K464 VanDerWaalsContact C-N 3.34Å; L462-K464 PolarHBondContact O-N 2.9Å; K464-L466 PolarHBondContact O-N 3.1Å; K464-R467 PolarHBondContact O-N 2.94Å; K464-D468 VanDerWaalsContact O-CG 3.25Å; K464-D468 PolarHBondContact O-N 3.24Å
465	L	89.9	Confident	87.9	Confident	2 Å²	2	57.2 Å²	57.2	1%	0.01	26%	0.26	C	S	.	.	H	α-helix	trans	-61.7	-43.7	177.4	-72.9	174	0	0	0	112.6	V331 T335 L421 L424 I425 E428 V461 L462 F463 D468 R469	V331-L465 HydrophobicContact CG1-CD1 3.81Å; T335-L465 HydrophobicContact CG2-CD2 3.46Å; T335-L465 VanDerWaalsContact CG2-CD2 3.46Å; T335-L465 HydrophobicContact CG2-CG 4.35Å; L421-L465 HydrophobicContact CD1-CD2 3.82Å; L424-L465 HydrophobicContact CB-CD1 4.4Å; L424-L465 HydrophobicContact CB-CD2 4.2Å; L424-L465 HydrophobicContact CD2-CD2 4.19Å; I425-L465 HydrophobicContact CD1-CB 4.43Å; I425-L465 HydrophobicContact CG1-CB 3.75Å; I425-L465 HydrophobicContact CG1-CD1 4.43Å; E428-L465 HydrophobicContact CB-CD1 3.99Å; E428-L465 HydrophobicContact CG-CD1 4.23Å; V461-L465 HydrophobicContact CG1-CD1 4.25Å; V461-L465 WeakPolarHBondContact O-CG 3.24Å; V461-L465 PolarHBondContact O-N 2.99Å; L462-L465 PolarHBondContact O-N 3.43Å; F463-L465 PolarHBondContact O-N 2.64Å; L465-D468 PolarHBondContact O-N 2.94Å; L465-R469 WeakPolarHBondContact O-CB 3.13Å; L465-R469 PolarHBondContact O-N 3.4Å
466	L	90.2	Very high	87.3	Confident	65 Å²	65	58.4 Å²	58.4	34%	0.34	26%	0.264	S	S	.	.	H	α-helix	trans	-65	-44.1	178.4	-75.3	171.9	0	0	0	111.8	I425 L462 F463 K464 R469 I470	I425-L466 HydrophobicContact CG2-CD2 4.3Å; L462-L466 HydrophobicContact CD1-CD1 4.22Å; L462-L466 HydrophobicContact CD1-CG 4.32Å; L462-L466 HydrophobicContact CG-CD1 3.99Å; L462-L466 HydrophobicContact CG-CG 4.49Å; L462-L466 WeakPolarHBondContact O-CB 3.26Å; L462-L466 VanDerWaalsContact O-CG 3.32Å; L462-L466 WeakPolarHBondContact O-CG 3.16Å; L462-L466 PolarHBondContact O-N 2.74Å; F463-L466 PolarHBondContact O-N 2.73Å; K464-L466 PolarHBondContact O-N 3.1Å; L466-R469 PolarHBondContact O-N 2.82Å; L466-I470 VanDerWaalsContact O-CG1 3.3Å; L466-I470 WeakPolarHBondContact O-CG1 3.35Å; L466-I470 PolarHBondContact O-N 3.35Å
467	R	89.9	Confident	86.4	Confident	67 Å²	67	54.4 Å²	54.4	25%	0.253	26%	0.255	S	S	.	.	H	α-helix	trans	-55.5	-52.3	174.3	178.5	-161	69.6	-176.2	3.1	110.4	F463 K464 R469 I470 V471	F463-R467 WeakPolarHBondContact O-CB 3.43Å; F463-R467 PolarHBondContact O-N 3.28Å; K464-R467 PolarHBondContact O-N 2.94Å; R467-R469 VanDerWaalsContact C-N 3.27Å; R467-R469 PolarHBondContact O-N 3.3Å; R467-I470 PolarHBondContact O-N 2.97Å; R467-V471 WeakPolarHBondContact O-CG2 3.4Å; R467-V471 PolarHBondContact O-N 3.23Å
468	D	85.3	Confident	85.1	Confident	24 Å²	24	61.5 Å²	61.5	13%	0.128	28%	0.279	C	S	.	.	H	α-helix	trans	-61.6	-38.8	-178.8	-66.7	-4.9	0	0	0	110.7	L421 K464 L465 I470 V471 L472	L421-D468 HydrophobicContact CD2-CB 4.48Å; K464-D468 VanDerWaalsContact O-CG 3.25Å; K464-D468 PolarHBondContact O-N 3.24Å; L465-D468 PolarHBondContact O-N 2.94Å; D468-I470 PolarHBondContact O-N 3.27Å; D468-V471 PolarHBondContact O-N 3.4Å; D468-L472 WeakPolarHBondContact O-CB 3.39Å; D468-L472 WeakPolarHBondContact O-CD1 3.45Å; D468-L472 PolarHBondContact O-N 3.29Å
469	R	89	Confident	83.4	Confident	111 Å²	111	62.6 Å²	62.6	42%	0.419	29%	0.287	S	S	.	.	H	α-helix	trans	-64.6	-40.9	176.2	177	-90.5	178.6	107.6	-2.8	113	L421 I425 L465 L466 R467 G473	L421-R469 VanDerWaalsContact CD2-CA 3.44Å; L421-R469 HydrophobicContact CD2-CB 3.69Å; L421-R469 HydrophobicContact CD2-CG 4.45Å; L421-R469 HydrophobicContact CG-CB 4.16Å; I425-R469 HydrophobicContact CD1-CB 3.53Å; I425-R469 HydrophobicContact CD1-CG 3.83Å; L465-R469 WeakPolarHBondContact O-CB 3.13Å; L465-R469 PolarHBondContact O-N 3.4Å; L466-R469 PolarHBondContact O-N 2.82Å; R467-R469 VanDerWaalsContact C-N 3.27Å; R467-R469 PolarHBondContact O-N 3.3Å; R469-G473 WeakPolarHBondContact O-CA 3.39Å; R469-G473 PolarHBondContact O-N 2.96Å
470	I	88.3	Confident	81.6	Confident	88 Å²	88	63.3 Å²	63.3	45%	0.451	30%	0.297	S	S	.	.	H	α-helix	trans	-67.1	-44	179.1	-68	164.1	0	0	0	109.8	L466 R467 D468 G473 R474	L466-I470 VanDerWaalsContact O-CG1 3.3Å; L466-I470 WeakPolarHBondContact O-CG1 3.35Å; L466-I470 PolarHBondContact O-N 3.35Å; R467-I470 PolarHBondContact O-N 2.97Å; D468-I470 PolarHBondContact O-N 3.27Å; I470-G473 PolarHBondContact O-N 3.27Å; I470-R474 WeakPolarHBondContact O-CG 3.33Å; I470-R474 PolarHBondContact O-N 3.19Å
471	V	86.3	Confident	79.4	Confident	49 Å²	49	63.9 Å²	63.9	30%	0.297	31%	0.306	S	S	.	.	H	α-helix	trans	-67.9	-50.8	-179	177.6	0	0	0	0	111.3	P65 L67 R467 D468 G473 R474 A475	P65-V471 HydrophobicContact CG-CG1 4.37Å; L67-V471 HydrophobicContact CD2-CB 3.79Å; L67-V471 HydrophobicContact CD2-CG1 3.55Å; L67-V471 HydrophobicContact CD2-CG2 4.18Å; L67-V471 HydrophobicContact CG-CG1 4.21Å; R467-V471 WeakPolarHBondContact O-CG2 3.4Å; R467-V471 PolarHBondContact O-N 3.23Å; D468-V471 PolarHBondContact O-N 3.4Å; V471-G473 VanDerWaalsContact C-N 3.29Å; V471-G473 PolarHBondContact O-N 3.15Å; V471-R474 PolarHBondContact O-N 3.33Å; V471-A475 WeakPolarHBondContact O-CB 3.45Å; V471-A475 PolarHBondContact O-N 3.31Å
472	L	83.1	Confident	77.1	Confident	6 Å²	6	66.4 Å²	66.4	3%	0.031	33%	0.325	C	S	.	.	H	α-helix	trans	-61.7	-40.5	175.7	-87.8	77.1	0	0	0	110.9	L67 L418 D468 R474 A475 Y476	L67-L472 HydrophobicContact CD1-CD1 3.31Å; L418-L472 HydrophobicContact CD2-CB 3.65Å; L418-L472 HydrophobicContact CD2-CD2 4.4Å; D468-L472 WeakPolarHBondContact O-CB 3.39Å; D468-L472 WeakPolarHBondContact O-CD1 3.45Å; D468-L472 PolarHBondContact O-N 3.29Å; L472-R474 PolarHBondContact O-N 3.14Å; L472-A475 PolarHBondContact O-N 2.87Å; L472-Y476 HydrophobicContact CB-CD2 4.33Å; L472-Y476 HydrophobicContact CB-CE2 4.36Å; L472-Y476 HydrophobicContact CD2-CE2 4.26Å; L472-Y476 HydrophobicContact CG-CE2 4.39Å; L472-Y476 WeakPolarHBondContact O-CD2 3.41Å; L472-Y476 PolarHBondContact O-N 3.02Å
473	G	83.5	Confident	74.9	Confident	14 Å²	14	70.1 Å²	70.1	14%	0.144	34%	0.337	C	S	.	.	H	α-helix	trans	-56	-50.2	177.3	0	0	0	0	0	111.7	R469 I470 V471 Y476 S477	R469-G473 WeakPolarHBondContact O-CA 3.39Å; R469-G473 PolarHBondContact O-N 2.96Å; I470-G473 PolarHBondContact O-N 3.27Å; V471-G473 VanDerWaalsContact C-N 3.29Å; V471-G473 PolarHBondContact O-N 3.15Å; G473-Y476 PolarHBondContact O-N 3.05Å; G473-S477 WeakPolarHBondContact O-CB 3.3Å; G473-S477 PolarHBondContact O-N 3.45Å; G473-S477 PolarHBondContact O-OG 3.23Å
474	R	83.4	Confident	72.5	Confident	170 Å²	170	70.2 Å²	70.2	64%	0.642	34%	0.34	S	S	*	.	H	α-helix	trans	-61.6	-46.1	175.3	-72.6	-179.4	179.4	178.5	0.8	111.8	I470 V471 L472 Y476 S477 Y478	I470-R474 WeakPolarHBondContact O-CG 3.33Å; I470-R474 PolarHBondContact O-N 3.19Å; V471-R474 PolarHBondContact O-N 3.33Å; L472-R474 PolarHBondContact O-N 3.14Å; R474-Y476 VanDerWaalsContact C-N 3.31Å; R474-Y476 PolarHBondContact O-N 3.49Å; R474-S477 PolarHBondContact O-N 2.9Å; R474-S477 VanDerWaalsContact O-N 3.09Å; R474-Y478 HydrophobicContact CB-CE2 4.48Å; R474-Y478 WeakPolarHBondContact O-CD2 3.35Å; R474-Y478 PolarHBondContact O-N 3.06Å; R474-Y478 VanDerWaalsContact O-N 3.08Å
475	A	79.8	Confident	70.3	Confident	17 Å²	17	75.9 Å²	75.9	14%	0.14	37%	0.37	C	S	.	.	H	α-helix	trans	-59	-39.1	-179.1	0	0	0	0	0	113.1	I64 V471 L472 P479	I64-A475 HydrophobicContact CG2-CB 4.45Å; V471-A475 WeakPolarHBondContact O-CB 3.45Å; V471-A475 PolarHBondContact O-N 3.31Å; L472-A475 PolarHBondContact O-N 2.87Å; A475-P479 VanDerWaalsContact O-CD 3.22Å; A475-P479 WeakPolarHBondContact O-CD 3.19Å
476	Y	77.1	Confident	67.8	Low	33 Å²	33	84.7 Å²	84.7	13%	0.129	41%	0.408	C	S	.	.	H	α-helix	trans	-82.5	-16.8	176.4	-71.6	-66.9	0	0	0	114	I64 D344 P417 L472 G473 R474 P479	I64-Y476 HydrophobicContact CD1-CE1 4.37Å; I64-Y476 HydrophobicContact CD1-CE2 4.1Å; I64-Y476 VanDerWaalsContact CD1-OH 3.28Å; I64-Y476 WeakPolarHBondContact CD1-OH 3.25Å; D344-Y476 PolarHBondContact OD1-OH 3.16Å; P417-Y476 HydrophobicContact CB-CD2 4.31Å; P417-Y476 HydrophobicContact CB-CE1 4.29Å; P417-Y476 HydrophobicContact CB-CE2 3.55Å; P417-Y476 WeakPolarHBondContact CB-OH 3.29Å; P417-Y476 HydrophobicContact CG-CD1 4Å; P417-Y476 HydrophobicContact CG-CD2 3.67Å; P417-Y476 HydrophobicContact CG-CE1 3.72Å; P417-Y476 HydrophobicContact CG-CE2 3.36Å; P417-Y476 HydrophobicContact CG-CG 3.98Å; L472-Y476 HydrophobicContact CB-CD2 4.33Å; L472-Y476 HydrophobicContact CB-CE2 4.36Å; L472-Y476 HydrophobicContact CD2-CE2 4.26Å; L472-Y476 HydrophobicContact CG-CE2 4.39Å; L472-Y476 WeakPolarHBondContact O-CD2 3.41Å; L472-Y476 PolarHBondContact O-N 3.02Å; G473-Y476 PolarHBondContact O-N 3.05Å; R474-Y476 VanDerWaalsContact C-N 3.31Å; R474-Y476 PolarHBondContact O-N 3.49Å; Y476-P479 WeakPolarHBondContact O-CD 3.4Å
477	S	72.6	Confident	65.4	Low	71 Å²	71	85.6 Å²	85.6	50%	0.497	43%	0.425	S	S	.	.	H	α-helix	trans	-82.7	-33.8	174.8	-66.4	0	0	0	0	114	G473 R474 P479 L480 N481	G473-S477 WeakPolarHBondContact O-CB 3.3Å; G473-S477 PolarHBondContact O-N 3.45Å; G473-S477 PolarHBondContact O-OG 3.23Å; R474-S477 PolarHBondContact O-N 2.9Å; R474-S477 VanDerWaalsContact O-N 3.09Å; S477-P479 VanDerWaalsContact C-CD 3.42Å; S477-L480 PolarHBondContact O-N 3.31Å; S477-N481 PolarHBondContact O-N 3.23Å
478	Y	60.2	Low	62.7	Low	175 Å²	175	92 Å²	92	69%	0.686	46%	0.464	S	S	*	.	H	α-helix	trans	-54	-42.6	178.7	-92.2	-74.3	0	0	0	115.5	R474 L480 S482	R474-Y478 HydrophobicContact CB-CE2 4.48Å; R474-Y478 WeakPolarHBondContact O-CD2 3.35Å; R474-Y478 PolarHBondContact O-N 3.06Å; R474-Y478 VanDerWaalsContact O-N 3.08Å; Y478-L480 PolarHBondContact O-N 2.76Å; Y478-S482 PolarHBondContact O-N 2.89Å; Y478-S482 PolarHBondContact O-OG 3.35Å
479	P	55.8	Low	61.6	Low	23 Å²	23	95.4 Å²	95.4	15%	0.149	48%	0.481	C	S	.	.	H	α-helix	trans	-59.2	-47.9	176.9	-16	23.5	0	0	0	111	C62 A475 Y476 S477 N481 S482 Y483	C62-P479 HydrophobicContact CB-CG 4.16Å; C62-P479 WeakPolarHBondContact SG-CG 3.03Å; A475-P479 VanDerWaalsContact O-CD 3.22Å; A475-P479 WeakPolarHBondContact O-CD 3.19Å; Y476-P479 WeakPolarHBondContact O-CD 3.4Å; S477-P479 VanDerWaalsContact C-CD 3.42Å; P479-N481 PolarHBondContact O-N 3.34Å; P479-S482 PolarHBondContact O-N 3.16Å; P479-S482 PolarHBondContact O-OG 3.24Å; P479-Y483 VanDerWaalsContact C-CD2 3.42Å; P479-Y483 HydrophobicContact CB-CD2 4.42Å; P479-Y483 HydrophobicContact CB-CE2 3.78Å; P479-Y483 WeakPolarHBondContact O-CD2 3.49Å; P479-Y483 VanDerWaalsContact O-CE2 3.25Å; P479-Y483 WeakPolarHBondContact O-CE2 3.42Å; P479-Y483 PolarHBondContact O-N 3.26Å
480	L	51.5	Low	60.2	Low	123 Å²	123	94.6 Å²	94.6	64%	0.644	48%	0.484	S	S	*	.	H	α-helix	trans	-56.9	-45	-177.5	-81.8	152.5	0	0	0	112.8	S477 Y478 Y483 E484	S477-L480 PolarHBondContact O-N 3.31Å; Y478-L480 PolarHBondContact O-N 2.76Å; L480-Y483 PolarHBondContact O-N 3.4Å; L480-E484 PolarHBondContact O-N 3.04Å
481	N	42.2	Very low	58.6	Low	106 Å²	106	94.9 Å²	94.9	57%	0.567	49%	0.486	S	S	*	.	H	α-helix	trans	-70.3	-34.9	178.5	-90.9	18.1	0	0	0	113.4	S477 P479 Y483 E484 L485	S477-N481 PolarHBondContact O-N 3.23Å; P479-N481 PolarHBondContact O-N 3.34Å; N481-Y483 PolarHBondContact O-N 3.49Å; N481-E484 PolarHBondContact O-N 2.89Å; N481-L485 PolarHBondContact O-N 3.03Å
482	S	41	Very low	57	Low	62 Å²	62	97.6 Å²	97.6	43%	0.434	50%	0.497	S	S	.	.	H	α-helix	trans	-68.1	-20.7	176.7	68.3	0	0	0	0	113.1	Y478 P479	Y478-S482 PolarHBondContact O-N 2.89Å; Y478-S482 PolarHBondContact O-OG 3.35Å; P479-S482 PolarHBondContact O-N 3.16Å; P479-S482 PolarHBondContact O-OG 3.24Å
483	Y	45.1	Very low	55.3	Low	109 Å²	109	103.4 Å²	103.4	43%	0.427	53%	0.527	S	S	.	.	H	α-helix	trans	-83.3	-34.2	175.3	-65.6	-58.5	0	0	0	112.8	P479 L480 N481 L485 K486 A487	P479-Y483 VanDerWaalsContact C-CD2 3.42Å; P479-Y483 HydrophobicContact CB-CD2 4.42Å; P479-Y483 HydrophobicContact CB-CE2 3.78Å; P479-Y483 WeakPolarHBondContact O-CD2 3.49Å; P479-Y483 VanDerWaalsContact O-CE2 3.25Å; P479-Y483 WeakPolarHBondContact O-CE2 3.42Å; P479-Y483 PolarHBondContact O-N 3.26Å; L480-Y483 PolarHBondContact O-N 3.4Å; N481-Y483 PolarHBondContact O-N 3.49Å; Y483-L485 VanDerWaalsContact C-N 3.3Å; Y483-L485 PolarHBondContact O-N 3.17Å; Y483-K486 PolarHBondContact O-N 3.25Å; Y483-A487 WeakPolarHBondContact O-CB 3.45Å; Y483-A487 PolarHBondContact O-N 3.36Å
484	E	40.1	Very low	53.5	Low	136 Å²	136	109.3 Å²	109.3	64%	0.636	55%	0.552	S	S	*	*	H	α-helix	trans	-66.3	-33.3	172.4	-74.6	-171.7	162	0	0	112.1	L480 N481 K486	L480-E484 PolarHBondContact O-N 3.04Å; N481-E484 PolarHBondContact O-N 2.89Å; E484-K486 VanDerWaalsContact C-N 3.33Å; E484-K486 PolarHBondContact O-N 3.09Å
485	L	41.1	Very low	51.3	Low	142 Å²	142	105 Å²	105	74%	0.743	55%	0.546	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.6	-13.4	177.1	-91.1	148.9	0	0	0	114.9	N481 Y483	N481-L485 PolarHBondContact O-N 3.03Å; Y483-L485 VanDerWaalsContact C-N 3.3Å; Y483-L485 PolarHBondContact O-N 3.17Å
486	K	38.4	Very low	49.1	Very low	188 Å²	188	111.8 Å²	111.8	82%	0.817	58%	0.577	S	S	*	*	T	Hydrogen-bonded Turn	trans	-104.7	-5.7	175.3	-101.8	-178	178.1	178.9	0	113.6	Y483 E484	Y483-K486 PolarHBondContact O-N 3.25Å; E484-K486 VanDerWaalsContact C-N 3.33Å; E484-K486 PolarHBondContact O-N 3.09Å
487	A	39.7	Very low	46.8	Very low	84 Å²	84	118.3 Å²	118.3	69%	0.694	61%	0.614	S	S	*	*			trans	-105.6	-3	179.3	0	0	0	0	0	113.3	Y483	Y483-A487 WeakPolarHBondContact O-CB 3.45Å; Y483-A487 PolarHBondContact O-N 3.36Å
488	N	33.9	Very low	44.5	Very low	201 Å²	201	122.6 Å²	122.6	100%	1.075	63%	0.625	S	S	*	*			trans	-100.8	0	159.9	-69	-24.7	0	0	0	108.9

Retrieved 488 of 488 residues in 3025.9 ms (Link to these results)

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