A0A096MWQ9_PAPAN Loading...

Asparagine synthetase domain-containing protein 1

AlphaFold DB , UniProt , Accession A0A096MWQ9, Species PAPAN (Papio anubis, Olive baboon), Gene ASNSD1, Length 643 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M78.6Confident91.2Very high2 Ų26.7 Ų6.71%0.014%0.044CC..  0142.70-172.9-162.3-103.600109.9L54 L56 N76 D538 G542 K546 E547M1-L54 HydrophobicContact CB-CD2 4.29Å; M1-L54 VanDerWaalsContact O-CB 3.31Å; M1-L54 WeakPolarHBondContact O-CB 3.22Å; M1-L54 PolarHBondContact O-N 3.34Å; M1-L56 HydrophobicContact CB-CD1 4.5Å; M1-N76 WeakPolarHBondContact CA-OD1 3.14Å; M1-N76 WeakPolarHBondContact CG-OD1 3.26Å; M1-D538 WeakPolarHBondContact CE-OD1 3.5Å; M1-G542 VanDerWaalsContact SD-CA 3.54Å; M1-K546 WeakPolarHBondContact CE-O 3.35Å; M1-E547 WeakPolarHBondContact CA-OE2 3.39Å; M1-E547 HydrophobicContact CB-CB 3.85Å; M1-E547 HydrophobicContact CB-CG 3.91Å; M1-E547 WeakPolarHBondContact CB-OE2 3.17Å; M1-E547 PolarHBondContact N-OE2 3.13Å
2C90.9Very high88.7Confident6 Ų613.5 Ų13.54%0.04110%0.101CC..EExtended strand (participates in β ladder)trans-148.5155.9177.8-71.60000110.6I4 H52 Q63 N76C2-I4 HydrophobicContact CB-CG2 4.05Å; C2-H52 CarbonylContact C-O 3.58Å; C2-H52 WeakPolarHBondContact CA-O 3.5Å; C2-H52 WeakPolarHBondContact CB-O 3.41Å; C2-Q63 PolarHBondContact SG-NE2 2.75Å; C2-Q63 VanDerWaalsContact SG-NE2 3.41Å; C2-N76 HydrophobicContact CB-CB 4.3Å; C2-N76 PolarHBondContact N-OD1 3Å; C2-N76 PolarHBondContact O-OD1 3.41Å
3G97.8Very high86.3Confident0 Ų024.9 Ų24.90%015%0.151CC..EExtended strand (participates in β ladder)trans-83.2112.916000000109.2G51 H52 S158G3-G51 CarbonylContact O-C 3.56Å; G3-H52 PolarHBondContact N-O 3.29Å; G3-H52 PolarHBondContact O-CD2 2.77Å; G3-H52 PolarHBondContact O-N 2.94Å; G3-S158 WeakPolarHBondContact CA-OG 3.48Å
4I98.6Very high84Confident0 Ų033.5 Ų33.50%019%0.188CC..EExtended strand (participates in β ladder)trans-118.2142.6177.464.4172000110.9C2 L27 S50 L74 N76 I122 L143 S157 S158C2-I4 HydrophobicContact CB-CG2 4.05Å; I4-L27 WeakPolarHBondContact O-CD2 3.45Å; I4-S50 CarbonylContact C-O 3.45Å; I4-L74 HydrophobicContact CB-CB 4.06Å; I4-L74 HydrophobicContact CB-CD2 4.12Å; I4-L74 HydrophobicContact CB-CG 4.5Å; I4-L74 HydrophobicContact CG2-CB 3.96Å; I4-L74 HydrophobicContact CG2-CD2 3.87Å; I4-N76 HydrophobicContact CD1-CB 3.86Å; I4-N76 HydrophobicContact CG1-CB 4.05Å; I4-N76 HydrophobicContact CG2-CB 4.12Å; I4-I122 HydrophobicContact CD1-CD1 4.29Å; I4-I122 HydrophobicContact CD1-CG1 4.22Å; I4-I122 HydrophobicContact CG1-CD1 4.46Å; I4-L143 HydrophobicContact CD1-CD1 4.35Å; I4-S157 CarbonylContact O-C 3.57Å; I4-S157 WeakPolarHBondContact O-CA 3.02Å; I4-S158 PolarHBondContact N-OG 3.14Å; I4-S158 PolarHBondContact O-N 2.85Å; I4-S158 PolarHBondContact O-OG 3.33Å
5C98.3Very high82.5Confident0 Ų034.1 Ų34.10%019%0.188CC..EExtended strand (participates in β ladder)trans-149.9142.4176.51780000111.7L19 L27 F49 S50 L74 L156C5-L19 HydrophobicContact CB-CD1 4.26Å; C5-L27 HydrophobicContact CB-CD1 3.54Å; C5-L27 HydrophobicContact CB-CD2 4.14Å; C5-F49 CarbonylContact O-C 3.58Å; C5-F49 WeakPolarHBondContact O-CA 3.44Å; C5-S50 PolarHBondContact N-O 2.82Å; C5-S50 PolarHBondContact O-N 3.3Å; C5-L74 WeakPolarHBondContact O-CD1 3.47Å; C5-L156 CarbonylContact C-O 3.55Å; C5-L156 WeakPolarHBondContact CA-O 3.38Å; C5-L156 PolarHBondContact SG-O 3.46Å
6C97.5Very high81.2Confident0 Ų036.7 Ų36.70%021%0.209CC..EExtended strand (participates in β ladder)trans-133.6116.2168.2177.50000108.9L48 F49 I122 C155 L156C6-L48 CarbonylContact C-O 3.48Å; C6-L48 WeakPolarHBondContact CA-O 3.46Å; C6-F49 HydrophobicContact CB-CD1 3.94Å; C6-F49 HydrophobicContact CB-CE1 4.11Å; C6-F49 WeakPolarHBondContact SG-CE1 3.12Å; C6-I122 HydrophobicContact CB-CD1 3.79Å; C6-I122 HydrophobicContact CB-CG2 3.87Å; C6-C155 CarbonylContact O-C 3.55Å; C6-C155 WeakPolarHBondContact O-CA 3.33Å; C6-L156 HydrophobicContact CB-CB 4.48Å; C6-L156 PolarHBondContact N-O 2.83Å; C6-L156 PolarHBondContact O-N 2.82Å
7S94.9Very high80.2Confident30 Ų3042.6 Ų42.621%0.2124%0.235CC..EExtended strand (participates in β ladder)trans-103.1125.5172.8-177.10000109.1C47 L48S7-C47 CarbonylContact O-C 3.58Å; S7-C47 VanDerWaalsContact O-CA 3.28Å; S7-C47 WeakPolarHBondContact O-CA 3.24Å; S7-L48 PolarHBondContact N-O 3.21Å; S7-L48 PolarHBondContact O-N 2.96Å
8V93.8Very high79.7Confident0 Ų046.4 Ų46.40%026%0.255CS..EExtended strand (participates in β ladder)trans-115.4131.5178-172.80000109.2F10 Q46 L131 S153 F154 L183V8-F10 HydrophobicContact CB-CZ 4.47Å; V8-F10 HydrophobicContact CG1-CD1 4.34Å; V8-F10 HydrophobicContact CG1-CE1 3.72Å; V8-F10 HydrophobicContact CG1-CE2 4.21Å; V8-F10 HydrophobicContact CG1-CZ 3.64Å; V8-Q46 CarbonylContact C-O 3.57Å; V8-Q46 WeakPolarHBondContact CA-O 3.4Å; V8-L131 HydrophobicContact CG2-CD2 4.01Å; V8-S153 CarbonylContact O-C 3.12Å; V8-S153 VanDerWaalsContact O-CA 3.27Å; V8-S153 WeakPolarHBondContact O-CA 3.34Å; V8-F154 HydrophobicContact CB-CB 4.37Å; V8-F154 HydrophobicContact CB-CD1 4.32Å; V8-F154 HydrophobicContact CG2-CD1 4.03Å; V8-F154 PolarHBondContact N-O 3.34Å; V8-F154 PolarHBondContact O-N 3.04Å; V8-L183 HydrophobicContact CG1-CD2 4.09Å; V8-L183 HydrophobicContact CG2-CD2 4.44Å
9N90.5Very high79.9Confident15 Ų1544.7 Ų44.78%0.0825%0.245CC..EExtended strand (participates in β ladder)trans-123.2130174.1-164.6-23.4000109.7S11 H14 F15 Y45 Q46 K152N9-S11 WeakPolarHBondContact OD1-CB 3.31Å; N9-S11 PolarHBondContact OD1-N 2.91Å; N9-S11 PolarHBondContact OD1-O 3.29Å; N9-H14 PolarHBondContact ND2-O 2.72Å; N9-F15 HydrophobicContact CB-CD2 3.52Å; N9-F15 HydrophobicContact CB-CE2 3.87Å; N9-Y45 CarbonylContact O-C 3.58Å; N9-Y45 VanDerWaalsContact O-CA 3.25Å; N9-Y45 WeakPolarHBondContact O-CA 3.27Å; N9-Y45 WeakPolarHBondContact O-CB 3.42Å; N9-Q46 PolarHBondContact N-O 3.43Å; N9-Q46 PolarHBondContact O-N 3.33Å; N9-K152 PolarHBondContact OD1-O 3.38Å
10F87.7Confident80.2Confident3 Ų350.3 Ų50.31%0.01327%0.267CS..SBendtrans-96.67.8178.8-56.5-69.7000112V8 K152 F154 L183 T186 A187 R190 I192V8-F10 HydrophobicContact CB-CZ 4.47Å; V8-F10 HydrophobicContact CG1-CD1 4.34Å; V8-F10 HydrophobicContact CG1-CE1 3.72Å; V8-F10 HydrophobicContact CG1-CE2 4.21Å; V8-F10 HydrophobicContact CG1-CZ 3.64Å; F10-K152 PolarHBondContact N-O 2.88Å; F10-F154 HydrophobicContact CE2-CB 4.24Å; F10-L183 HydrophobicContact CE1-CD2 4.25Å; F10-L183 HydrophobicContact CZ-CD2 4.24Å; F10-T186 HydrophobicContact CD1-CG2 4.09Å; F10-T186 HydrophobicContact CD2-CG2 4.11Å; F10-T186 HydrophobicContact CE1-CG2 3.56Å; F10-T186 HydrophobicContact CE2-CG2 3.58Å; F10-T186 HydrophobicContact CG-CG2 4.35Å; F10-T186 HydrophobicContact CZ-CG2 3.28Å; F10-A187 HydrophobicContact CD1-CB 3.85Å; F10-R190 VanDerWaalsContact O-CZ 3.25Å; F10-R190 PolarHBondContact O-NH1 3.49Å; F10-R190 PolarHBondContact O-NH2 3.43Å; F10-I192 HydrophobicContact CE2-CD1 4.39Å; F10-I192 HydrophobicContact CE2-CG1 4.35Å
11S74.8Confident80.6Confident18 Ų1855.8 Ų55.813%0.12629%0.291CS..  trans-128.5120.2-176.7-176.40000111.2N9 E13N9-S11 WeakPolarHBondContact OD1-CB 3.31Å; N9-S11 PolarHBondContact OD1-N 2.91Å; N9-S11 PolarHBondContact OD1-O 3.29Å; S11-E13 VanDerWaalsContact C-N 3.29Å; S11-E13 PolarHBondContact O-N 2.81Å
12A60.7Low81.1Confident88 Ų8860.8 Ų60.873%0.72732%0.318SS*.G310 helixtrans-66.6-25.3-177.800000114.1H14A12-H14 PolarHBondContact O-N 2.82Å
13E58.3Low81.1Confident162 Ų16261 Ų6176%0.75732%0.319SS*.G310 helixtrans-78.8-10.2-168.5-66.5179.6169.200115.3S11S11-E13 VanDerWaalsContact C-N 3.29Å; S11-E13 PolarHBondContact O-N 2.81Å
14H54.3Low81Confident145 Ų14562.7 Ų62.767%0.67133%0.328SS*.G310 helixtrans-144.840.2-168.9-65.373.7000113.7N9 A12N9-H14 PolarHBondContact ND2-O 2.72Å; A12-H14 PolarHBondContact O-N 2.82Å
15F60.6Low80.8Confident42 Ų4268.6 Ų68.618%0.18435%0.351CS..  trans-87.5113.2177.2-164.9-98000112.1N9 Q17 F39 Q46 L48N9-F15 HydrophobicContact CB-CD2 3.52Å; N9-F15 HydrophobicContact CB-CE2 3.87Å; F15-Q17 HydrophobicContact CD1-CG 4.15Å; F15-Q17 HydrophobicContact CE1-CG 4.33Å; F15-F39 AromaticContact CD1-CE2 3.88Å; F15-F39 HydrophobicContact CD1-CE2 3.88Å; F15-F39 AromaticContact CE1-CD2 3.71Å; F15-F39 HydrophobicContact CE1-CD2 3.71Å; F15-F39 AromaticContact CE1-CE2 3.25Å; F15-F39 HydrophobicContact CE1-CE2 3.25Å; F15-F39 HydrophobicContact CE1-CZ 4.32Å; F15-F39 HydrophobicContact CE2-CE2 4.5Å; F15-F39 HydrophobicContact CZ-CD2 4.01Å; F15-F39 AromaticContact CZ-CE2 3.61Å; F15-F39 HydrophobicContact CZ-CE2 3.61Å; F15-Q46 HydrophobicContact CD2-CB 3.82Å; F15-Q46 HydrophobicContact CE2-CB 3.76Å; F15-Q46 HydrophobicContact CG-CB 4.31Å; F15-Q46 HydrophobicContact CZ-CB 4.21Å; F15-L48 HydrophobicContact CZ-CB 3.93Å
16S62.6Low80.7Confident76 Ų7668.8 Ų68.853%0.53135%0.352SS..  trans-75.2121.4160.7179.40000108.1D18S16-D18 WeakPolarHBondContact CB-O 3.49Å; S16-D18 PolarHBondContact O-N 2.83Å; S16-D18 PolarHBondContact OG-N 3.45Å; S16-D18 PolarHBondContact OG-O 3.13Å
17Q64.4Low80.7Confident138 Ų13868.8 Ų68.865%0.64535%0.352SS*.SBendtrans-65.9-14.5171.6-74.7-178.3-12.900112.6F15 L48F15-Q17 HydrophobicContact CD1-CG 4.15Å; F15-Q17 HydrophobicContact CE1-CG 4.33Å; Q17-L48 VanDerWaalsContact O-CD2 3.29Å; Q17-L48 WeakPolarHBondContact O-CD2 3.22Å
18D70.6Confident80.8Confident111 Ų11171.7 Ų71.759%0.59436%0.36SS*.SBendtrans-111143.5-179.8-62.6-47.2000112.2S16S16-D18 WeakPolarHBondContact CB-O 3.49Å; S16-D18 PolarHBondContact O-N 2.83Å; S16-D18 PolarHBondContact OG-N 3.45Å; S16-D18 PolarHBondContact OG-O 3.13Å
19L82.7Confident81Confident14 Ų1474.6 Ų74.67%0.07337%0.374CS..  trans-66.8150.1164.5-66.1178000109.7C5 E21 L23 L24 L27 L48C5-L19 HydrophobicContact CB-CD1 4.26Å; L19-E21 PolarHBondContact O-N 2.92Å; L19-L23 HydrophobicContact CD2-CD2 4.29Å; L19-L24 HydrophobicContact CB-CB 4.41Å; L19-L27 HydrophobicContact CD1-CD1 3.85Å; L19-L48 HydrophobicContact CD2-CD2 3.89Å; L19-L48 HydrophobicContact CG-CD2 3.8Å
20K86.3Confident81.3Confident155 Ų15574 Ų7467%0.67437%0.371SS*.  trans-52.8136.6170.1-66.2-175.1178.1-177.40110D22 L23 L24K20-D22 VanDerWaalsContact C-N 3.31Å; K20-D22 PolarHBondContact O-N 3.17Å; K20-L23 HydrophobicContact CB-CB 4.49Å; K20-L23 WeakPolarHBondContact O-CB 3.48Å; K20-L23 PolarHBondContact O-N 3.08Å; K20-L24 PolarHBondContact O-N 2.96Å
21E88.1Confident81.8Confident166 Ų16674 Ų7478%0.77637%0.371SS*.Hα-helixtrans-53.4-45.2-173.8-68-175.9168.800112.9L19 L23 L24 Y25L19-E21 PolarHBondContact O-N 2.92Å; E21-L23 VanDerWaalsContact C-N 3.3Å; E21-L23 PolarHBondContact O-N 2.6Å; E21-L24 PolarHBondContact O-N 3.06Å; E21-Y25 WeakPolarHBondContact O-CB 3.31Å; E21-Y25 PolarHBondContact O-N 3.03Å
22D89.3Confident82.8Confident108 Ų10876.9 Ų76.958%0.57839%0.39SS*.Hα-helixtrans-60.2-39.1178.6-65.3-27000112.7K20 N26 T161K20-D22 VanDerWaalsContact C-N 3.31Å; K20-D22 PolarHBondContact O-N 3.17Å; D22-N26 PolarHBondContact O-N 2.88Å; D22-N26 PolarHBondContact O-ND2 2.91Å; D22-N26 PolarHBondContact O-OD1 3.02Å; D22-T161 HydrophobicContact CB-CG2 3.69Å
23L92.6Very high84.5Confident10 Ų1075.8 Ų75.85%0.05237%0.371CS..Hα-helixtrans-70.1-45.1179.7178.661000109.9L19 K20 E21 Y25 N26 L27 V159 T161 W170L19-L23 HydrophobicContact CD2-CD2 4.29Å; K20-L23 HydrophobicContact CB-CB 4.49Å; K20-L23 WeakPolarHBondContact O-CB 3.48Å; K20-L23 PolarHBondContact O-N 3.08Å; E21-L23 VanDerWaalsContact C-N 3.3Å; E21-L23 PolarHBondContact O-N 2.6Å; L23-Y25 VanDerWaalsContact C-N 3.3Å; L23-Y25 PolarHBondContact O-N 2.77Å; L23-N26 PolarHBondContact O-N 2.97Å; L23-L27 HydrophobicContact CD1-CD1 4.32Å; L23-L27 HydrophobicContact CD1-CG 4.46Å; L23-L27 HydrophobicContact CG-CD1 4.03Å; L23-L27 VanDerWaalsContact O-CG 3.28Å; L23-L27 WeakPolarHBondContact O-CG 3.43Å; L23-L27 PolarHBondContact O-N 3.5Å; L23-V159 WeakPolarHBondContact CD1-O 3.35Å; L23-T161 VanDerWaalsContact CA-CG2 3.44Å; L23-T161 HydrophobicContact CB-CG2 3.72Å; L23-T161 HydrophobicContact CD1-CG2 4.27Å; L23-T161 VanDerWaalsContact N-CG2 3.32Å; L23-W170 HydrophobicContact CD1-CH2 4.45Å; L23-W170 HydrophobicContact CD1-CZ2 4.27Å; L23-W170 HydrophobicContact CD2-CH2 4.29Å; L23-W170 HydrophobicContact CD2-CZ2 4.25Å
24L94.7Very high86.3Confident36 Ų3669.3 Ų69.319%0.18834%0.344CS..Hα-helixtrans-60.7-41.3176.5-176.661.7000111.5L19 K20 E21 L27 K28 H52L19-L24 HydrophobicContact CB-CB 4.41Å; K20-L24 PolarHBondContact O-N 2.96Å; E21-L24 PolarHBondContact O-N 3.06Å; L24-L27 PolarHBondContact O-N 2.93Å; L24-K28 HydrophobicContact CG-CD 4.36Å; L24-K28 WeakPolarHBondContact O-CG 3.32Å; L24-K28 PolarHBondContact O-N 3.4Å; L24-H52 VanDerWaalsContact CD1-CE1 3.47Å; L24-H52 WeakPolarHBondContact CD1-CE1 3.4Å
25Y95.3Very high88.3Confident124 Ų12465.3 Ų65.349%0.48633%0.332SS..Hα-helixtrans-60.6-49174.9178.9-106.9000111.2E21 L23 L27 K28 Q29 R444E21-Y25 WeakPolarHBondContact O-CB 3.31Å; E21-Y25 PolarHBondContact O-N 3.03Å; L23-Y25 VanDerWaalsContact C-N 3.3Å; L23-Y25 PolarHBondContact O-N 2.77Å; Y25-L27 VanDerWaalsContact C-N 3.29Å; Y25-L27 PolarHBondContact O-N 3.25Å; Y25-K28 PolarHBondContact O-N 3.4Å; Y25-Q29 HydrophobicContact CE1-CG 4.16Å; Y25-Q29 HydrophobicContact CE2-CG 4.32Å; Y25-Q29 WeakPolarHBondContact O-CG 3.2Å; Y25-Q29 PolarHBondContact O-N 3.08Å; Y25-R444 VanDerWaalsContact CD1-NH1 3.28Å; Y25-R444 VanDerWaalsContact CE1-CZ 3.41Å
26N95.8Very high90.1Very high3 Ų367 Ų672%0.01634%0.34CS..Hα-helixtrans-58.9-40.4177.7-66.5-7.9000112.7D22 L23 V159 G160 R444D22-N26 PolarHBondContact O-N 2.88Å; D22-N26 PolarHBondContact O-ND2 2.91Å; D22-N26 PolarHBondContact O-OD1 3.02Å; L23-N26 PolarHBondContact O-N 2.97Å; N26-V159 HydrophobicContact CB-CB 4.48Å; N26-V159 HydrophobicContact CB-CG1 3.61Å; N26-V159 HydrophobicContact CB-CG2 4Å; N26-G160 PolarHBondContact ND2-O 3.25Å; N26-R444 VanDerWaalsContact OD1-CZ 3.25Å; N26-R444 PolarHBondContact OD1-NH1 3.19Å; N26-R444 PolarHBondContact OD1-NH2 3.19Å
27L97.4Very high91.7Very high0 Ų066.8 Ų66.80%033%0.33CS..Hα-helixtrans-67.6-42.5177.8-69.9163.9000112.3I4 C5 L19 L23 L24 Y25 Q29 R30 G31 H52 S158 V159I4-L27 WeakPolarHBondContact O-CD2 3.45Å; C5-L27 HydrophobicContact CB-CD1 3.54Å; C5-L27 HydrophobicContact CB-CD2 4.14Å; L19-L27 HydrophobicContact CD1-CD1 3.85Å; L23-L27 HydrophobicContact CD1-CD1 4.32Å; L23-L27 HydrophobicContact CD1-CG 4.46Å; L23-L27 HydrophobicContact CG-CD1 4.03Å; L23-L27 VanDerWaalsContact O-CG 3.28Å; L23-L27 WeakPolarHBondContact O-CG 3.43Å; L23-L27 PolarHBondContact O-N 3.5Å; L24-L27 PolarHBondContact O-N 2.93Å; Y25-L27 VanDerWaalsContact C-N 3.29Å; Y25-L27 PolarHBondContact O-N 3.25Å; L27-Q29 VanDerWaalsContact C-N 3.31Å; L27-Q29 PolarHBondContact O-N 3.29Å; L27-R30 WeakPolarHBondContact O-CB 3.43Å; L27-R30 PolarHBondContact O-N 2.83Å; L27-G31 PolarHBondContact O-N 2.92Å; L27-H52 WeakPolarHBondContact CB-CD2 3.49Å; L27-H52 WeakPolarHBondContact O-CB 3.38Å; L27-S158 WeakPolarHBondContact CD2-OG 3.17Å; L27-V159 HydrophobicContact CD2-CG1 3.94Å; L27-V159 HydrophobicContact CG-CG1 4.14Å
28K97.3Very high93.2Very high91 Ų9161.5 Ų61.540%0.39631%0.307SS..Hα-helixtrans-62.9-36.2177.4-76.8178.1178.1179.40112.6L24 Y25 R30 G31 H52L24-K28 HydrophobicContact CG-CD 4.36Å; L24-K28 WeakPolarHBondContact O-CG 3.32Å; L24-K28 PolarHBondContact O-N 3.4Å; Y25-K28 PolarHBondContact O-N 3.4Å; K28-R30 PolarHBondContact O-N 2.81Å; K28-G31 CarbonylContact O-C 3.49Å; K28-G31 PolarHBondContact O-N 3.17Å; K28-G31 VanDerWaalsContact O-N 3.12Å; K28-H52 WeakPolarHBondContact CG-ND1 3.29Å
29Q96.9Very high94.4Very high62 Ų6259.9 Ų59.929%0.2929%0.294SS..Hα-helixtrans-60.8-34.5175.8-72.8-57.710900112.7Y25 L27 G31 G542 D543 G545Y25-Q29 HydrophobicContact CE1-CG 4.16Å; Y25-Q29 HydrophobicContact CE2-CG 4.32Å; Y25-Q29 WeakPolarHBondContact O-CG 3.2Å; Y25-Q29 PolarHBondContact O-N 3.08Å; L27-Q29 VanDerWaalsContact C-N 3.31Å; L27-Q29 PolarHBondContact O-N 3.29Å; Q29-G31 VanDerWaalsContact C-N 3.35Å; Q29-G542 CarbonylContact C-O 3.53Å; Q29-D543 WeakPolarHBondContact CB-OD1 2.67Å; Q29-D543 PolarHBondContact NE2-O 3.26Å; Q29-D543 VanDerWaalsContact NE2-O 3.15Å; Q29-G545 WeakPolarHBondContact O-CA 3.48Å; Q29-G545 PolarHBondContact O-N 3.3Å; Q29-G545 VanDerWaalsContact O-N 3.13Å
30R97.4Very high94.9Very high2 Ų261.3 Ų61.31%0.00830%0.3CS..Hα-helixtrans-71.9-27.6175.6-62.9175.663.876.9-3.7113.8L27 K28 L54 N76 S158 D538 G542L27-R30 WeakPolarHBondContact O-CB 3.43Å; L27-R30 PolarHBondContact O-N 2.83Å; K28-R30 PolarHBondContact O-N 2.81Å; R30-L54 WeakPolarHBondContact O-CB 3.47Å; R30-N76 PolarHBondContact NH2-ND2 3.38Å; R30-S158 PolarHBondContact NE-OG 3.46Å; R30-D538 IonicContact CZ-OD2 3.13Å; R30-D538 PolarHBondContact NH1-O 2.72Å; R30-D538 IonicContact NH1-OD2 2.67Å; R30-D538 IonicContact NH2-OD1 2.98Å; R30-D538 IonicContact NH2-OD2 2.81Å; R30-D538 PolarHBondContact NH2-OD2 3.32Å; R30-G542 VanDerWaalsContact CA-O 3.24Å; R30-G542 WeakPolarHBondContact CA-O 3.36Å
31G97.1Very high95.1Very high2 Ų257.7 Ų57.72%0.02129%0.294CS..  trans-141.976.3-174.300000112.7L27 K28 Q29 N33 H52 V53L27-G31 PolarHBondContact O-N 2.92Å; K28-G31 CarbonylContact O-C 3.49Å; K28-G31 PolarHBondContact O-N 3.17Å; K28-G31 VanDerWaalsContact O-N 3.12Å; Q29-G31 VanDerWaalsContact C-N 3.35Å; G31-N33 VanDerWaalsContact C-N 3.31Å; G31-N33 PolarHBondContact O-N 3.27Å; G31-H52 WeakPolarHBondContact CA-O 3.39Å; G31-V53 CarbonylContact C-O 3.59Å; G31-V53 WeakPolarHBondContact CA-O 3.38Å; G31-V53 PolarHBondContact O-N 2.76Å
32P95.9Very high95.2Very high79 Ų7951.9 Ų51.951%0.51327%0.269SS..THydrogen-bonded Turntrans-79-7.9-172.730.8-36.5000114.4L54P32-L54 HydrophobicContact CG-CD1 4.32Å
33N96.5Very high95Very high65 Ų6553.2 Ų53.235%0.34828%0.28SS..THydrogen-bonded Turntrans-84.8-28.6-172.8-59.1130.4000113.8G31 V53 H55 L60 K488G31-N33 VanDerWaalsContact C-N 3.31Å; G31-N33 PolarHBondContact O-N 3.27Å; N33-V53 WeakPolarHBondContact CA-O 3.44Å; N33-V53 VanDerWaalsContact CB-O 3.28Å; N33-V53 WeakPolarHBondContact CB-O 3.49Å; N33-V53 PolarHBondContact N-O 2.71Å; N33-H55 HydrophobicContact CB-CB 4.22Å; N33-H55 PolarHBondContact OD1-N 3.25Å; N33-L60 HydrophobicContact CB-CD1 4.21Å; N33-K488 PolarHBondContact OD1-NZ 2.65Å
34S96.8Very high94.6Very high27 Ų2755.9 Ų55.919%0.18929%0.294CS..EExtended strand (participates in β ladder)trans-155151.2175.2-174.90000110.2H52 V53 T62S34-H52 CarbonylContact O-C 3.54Å; S34-H52 VanDerWaalsContact O-CA 3.24Å; S34-H52 WeakPolarHBondContact O-CA 3.18Å; S34-V53 PolarHBondContact N-O 3.45Å; S34-V53 PolarHBondContact O-N 3.39Å; S34-T62 VanDerWaalsContact OG-CG2 3.31Å; S34-T62 WeakPolarHBondContact OG-CG2 3.43Å
35S96.8Very high94.5Very high60 Ų6054.3 Ų54.342%0.4229%0.286SS..EExtended strand (participates in β ladder)trans-141.6123.8179.4179.30000108.6G51 H52S35-G51 WeakPolarHBondContact CA-O 3.28Å; S35-H52 PolarHBondContact OG-CE1 2.9Å; S35-H52 PolarHBondContact OG-ND1 3.28Å
36K96.8Very high94.4Very high77 Ų7750.5 Ų50.534%0.33527%0.273SS..EExtended strand (participates in β ladder)trans-141.7145.1175.9175.5-171.9176.8-163.90110G51 Q63 P64K36-G51 PolarHBondContact N-O 3.49Å; K36-G51 PolarHBondContact O-N 2.94Å; K36-Q63 WeakPolarHBondContact CB-O 3.21Å; K36-P64 PolarHBondContact NZ-O 3.34Å; K36-P64 WeakPolarHBondContact O-CD 3.33Å
37Q96.4Very high94.3Very high72 Ų7250.4 Ų50.434%0.33627%0.272SS..EExtended strand (participates in β ladder)trans-119.8147.2172.4-76.7173.8-33.500109.6L48 F49 S50Q37-L48 HydrophobicContact CB-CD1 4.21Å; Q37-F49 CarbonylContact C-O 3.5Å; Q37-F49 VanDerWaalsContact CA-O 3.22Å; Q37-F49 WeakPolarHBondContact CA-O 3.35Å; Q37-S50 WeakPolarHBondContact CG-OG 3.31Å; Q37-S50 PolarHBondContact NE2-OG 2.97Å
38L96.4Very high94.3Very high28 Ų2850.7 Ų50.715%0.14727%0.274CS..EExtended strand (participates in β ladder)trans-137.1127.4178.9-179.265.5000109.1F49 P64 E66 V72L38-F49 HydrophobicContact CB-CB 4.37Å; L38-F49 PolarHBondContact N-O 3.22Å; L38-F49 PolarHBondContact O-N 3.46Å; L38-P64 HydrophobicContact CB-CB 4.44Å; L38-P64 HydrophobicContact CB-CG 4Å; L38-P64 HydrophobicContact CD2-CB 4.42Å; L38-E66 WeakPolarHBondContact CD1-OE2 3.24Å; L38-E66 HydrophobicContact CD2-CB 4.19Å; L38-E66 HydrophobicContact CD2-CG 4.5Å; L38-E66 VanDerWaalsContact CD2-OE2 3.31Å; L38-E66 WeakPolarHBondContact CD2-OE2 3.25Å; L38-V72 HydrophobicContact CD2-CB 4.37Å; L38-V72 HydrophobicContact CD2-CG1 3.85Å; L38-V72 HydrophobicContact CD2-CG2 3.55Å
39F95.3Very high94.3Very high76 Ų7646.4 Ų46.433%0.33326%0.255SS..EExtended strand (participates in β ladder)trans-101.2135.7177.7-180-103000110.5F15 Q46 C47F15-F39 AromaticContact CD1-CE2 3.88Å; F15-F39 HydrophobicContact CD1-CE2 3.88Å; F15-F39 AromaticContact CE1-CD2 3.71Å; F15-F39 HydrophobicContact CE1-CD2 3.71Å; F15-F39 AromaticContact CE1-CE2 3.25Å; F15-F39 HydrophobicContact CE1-CE2 3.25Å; F15-F39 HydrophobicContact CE1-CZ 4.32Å; F15-F39 HydrophobicContact CE2-CE2 4.5Å; F15-F39 HydrophobicContact CZ-CD2 4.01Å; F15-F39 AromaticContact CZ-CE2 3.61Å; F15-F39 HydrophobicContact CZ-CE2 3.61Å; F39-Q46 HydrophobicContact CE2-CB 3.94Å; F39-Q46 HydrophobicContact CE2-CG 4.27Å; F39-Q46 HydrophobicContact CZ-CB 4.06Å; F39-Q46 HydrophobicContact CZ-CG 3.88Å; F39-C47 WeakPolarHBondContact CA-O 3.41Å; F39-C47 WeakPolarHBondContact CD2-O 3.35Å
40K94.1Very high94.4Very high44 Ų4443.5 Ų43.519%0.19124%0.241CC..EExtended strand (participates in β ladder)trans-128.4137.9171.1-67-64.1-172.2-179.60109.1C47 F49 E66 V72 Y124K40-C47 HydrophobicContact CB-CB 4.29Å; K40-C47 PolarHBondContact N-O 3.5Å; K40-C47 PolarHBondContact O-N 2.96Å; K40-F49 HydrophobicContact CB-CE2 4.08Å; K40-F49 HydrophobicContact CG-CD2 4.28Å; K40-F49 HydrophobicContact CG-CE2 3.82Å; K40-E66 WeakPolarHBondContact CE-OE1 3.41Å; K40-E66 IonicContact NZ-OE1 2.78Å; K40-E66 PolarHBondContact NZ-OE1 3.03Å; K40-E66 IonicContact NZ-OE2 3.24Å; K40-V72 HydrophobicContact CG-CG2 4.19Å; K40-Y124 HydrophobicContact CG-CE1 4.42Å
41S90.6Very high94.4Very high79 Ų7943.4 Ų43.455%0.55224%0.241SC*.EExtended strand (participates in β ladder)trans-131.2138.917754.70000110.8
42D89.4Confident94.5Very high45 Ų4543.3 Ų43.324%0.24124%0.24CC..  trans-113.8171.5162.1-178.1-104000108.7N44 Y45 H129D42-N44 PolarHBondContact O-N 2.82Å; D42-N44 PolarHBondContact OD1-N 2.99Å; D42-N44 PolarHBondContact OD1-ND2 3.38Å; D42-N44 VanDerWaalsContact OD1-ND2 3.16Å; D42-Y45 HydrophobicContact CB-CD1 3.87Å; D42-Y45 HydrophobicContact CB-CD2 4.41Å; D42-Y45 HydrophobicContact CB-CE1 3.57Å; D42-Y45 HydrophobicContact CB-CE2 4.13Å; D42-Y45 HydrophobicContact CB-CG 4.28Å; D42-Y45 PolarHBondContact N-O 3.32Å; D42-Y45 VanDerWaalsContact O-O 3.09Å; D42-H129 IonicContact OD2-CE1 3.55Å; D42-H129 PolarHBondContact OD2-CE1 2.96Å
43V85.3Confident94.6Very high135 Ų13539.9 Ų39.982%0.81822%0.217SC*.SBendtrans-55-34172.7179.20000111.7
44N85.6Confident94.6Very high66 Ų6637 Ų3735%0.35320%0.202SC..SBendtrans-107.9-14-169.5-53-71.3000114.7D42 A187D42-N44 PolarHBondContact O-N 2.82Å; D42-N44 PolarHBondContact OD1-N 2.99Å; D42-N44 PolarHBondContact OD1-ND2 3.38Å; D42-N44 VanDerWaalsContact OD1-ND2 3.16Å; N44-A187 HydrophobicContact CB-CB 3.53Å; N44-A187 WeakPolarHBondContact O-CB 3.45Å
45Y91.6Very high94.4Very high4 Ų437.5 Ų37.52%0.01620%0.201CC..  trans-153.7163.3-17968.7-96.7000112.2N9 D42 C47 Y124 H129 L183N9-Y45 CarbonylContact O-C 3.58Å; N9-Y45 VanDerWaalsContact O-CA 3.25Å; N9-Y45 WeakPolarHBondContact O-CA 3.27Å; N9-Y45 WeakPolarHBondContact O-CB 3.42Å; D42-Y45 HydrophobicContact CB-CD1 3.87Å; D42-Y45 HydrophobicContact CB-CD2 4.41Å; D42-Y45 HydrophobicContact CB-CE1 3.57Å; D42-Y45 HydrophobicContact CB-CE2 4.13Å; D42-Y45 HydrophobicContact CB-CG 4.28Å; D42-Y45 PolarHBondContact N-O 3.32Å; D42-Y45 VanDerWaalsContact O-O 3.09Å; Y45-C47 VanDerWaalsContact CD2-SG 3.56Å; Y45-C47 VanDerWaalsContact CE2-SG 3.56Å; Y45-Y124 HydrophobicContact CE2-CE2 4.38Å; Y45-Y124 WeakPolarHBondContact OH-CE2 3.41Å; Y45-Y124 PolarHBondContact OH-OH 2.91Å; Y45-H129 HydrophobicContact CE1-CB 4.25Å; Y45-H129 AromaticContact CE1-ND1 3.69Å; Y45-H129 AromaticContact CZ-ND1 3.63Å; Y45-H129 WeakPolarHBondContact OH-CB 3.33Å; Y45-H129 PolarHBondContact OH-ND1 3.15Å; Y45-L183 HydrophobicContact CD1-CB 3.81Å; Y45-L183 HydrophobicContact CD2-CB 4.29Å; Y45-L183 HydrophobicContact CD2-CD1 4.03Å; Y45-L183 HydrophobicContact CE1-CB 3.58Å; Y45-L183 HydrophobicContact CE2-CB 4.11Å; Y45-L183 HydrophobicContact CE2-CD1 3.58Å; Y45-L183 HydrophobicContact CG-CB 4.16Å
46Q92.9Very high94.2Very high44 Ų4434.8 Ų34.821%0.20618%0.182CC..EExtended strand (participates in β ladder)trans-131.2142.2176.4-68.7171.3-33.800109.8V8 N9 F15 F39V8-Q46 CarbonylContact C-O 3.57Å; V8-Q46 WeakPolarHBondContact CA-O 3.4Å; N9-Q46 PolarHBondContact N-O 3.43Å; N9-Q46 PolarHBondContact O-N 3.33Å; F15-Q46 HydrophobicContact CD2-CB 3.82Å; F15-Q46 HydrophobicContact CE2-CB 3.76Å; F15-Q46 HydrophobicContact CG-CB 4.31Å; F15-Q46 HydrophobicContact CZ-CB 4.21Å; F39-Q46 HydrophobicContact CE2-CB 3.94Å; F39-Q46 HydrophobicContact CE2-CG 4.27Å; F39-Q46 HydrophobicContact CZ-CB 4.06Å; F39-Q46 HydrophobicContact CZ-CG 3.88Å
47C94.9Very high93.9Very high0 Ų031.7 Ų31.70%017%0.168CC..EExtended strand (participates in β ladder)trans-126.5131.5179.2-59.10000110.5S7 F39 K40 Y45 F49S7-C47 CarbonylContact O-C 3.58Å; S7-C47 VanDerWaalsContact O-CA 3.28Å; S7-C47 WeakPolarHBondContact O-CA 3.24Å; F39-C47 WeakPolarHBondContact CA-O 3.41Å; F39-C47 WeakPolarHBondContact CD2-O 3.35Å; K40-C47 HydrophobicContact CB-CB 4.29Å; K40-C47 PolarHBondContact N-O 3.5Å; K40-C47 PolarHBondContact O-N 2.96Å; Y45-C47 VanDerWaalsContact CD2-SG 3.56Å; Y45-C47 VanDerWaalsContact CE2-SG 3.56Å; C47-F49 HydrophobicContact CB-CD2 4.21Å; C47-F49 HydrophobicContact CB-CE2 3.47Å; C47-F49 VanDerWaalsContact CB-CE2 3.47Å; C47-F49 HydrophobicContact CB-CZ 3.81Å
48L96.2Very high93.6Very high7 Ų729.3 Ų29.34%0.03716%0.163CC..EExtended strand (participates in β ladder)trans-113115.9166.9176.967.4000109C6 S7 F15 Q17 L19 Q37C6-L48 CarbonylContact C-O 3.48Å; C6-L48 WeakPolarHBondContact CA-O 3.46Å; S7-L48 PolarHBondContact N-O 3.21Å; S7-L48 PolarHBondContact O-N 2.96Å; F15-L48 HydrophobicContact CZ-CB 3.93Å; Q17-L48 VanDerWaalsContact O-CD2 3.29Å; Q17-L48 WeakPolarHBondContact O-CD2 3.22Å; L19-L48 HydrophobicContact CD2-CD2 3.89Å; L19-L48 HydrophobicContact CG-CD2 3.8Å; Q37-L48 HydrophobicContact CB-CD1 4.21Å
49F97.9Very high93.3Very high1 Ų133.4 Ų33.40%0.00419%0.189CC..EExtended strand (participates in β ladder)trans-99.3132.5174.5-58.9-87.7000109.2C5 C6 Q37 L38 K40 C47 P64 V72 L74 I122 Y124 L131C5-F49 CarbonylContact O-C 3.58Å; C5-F49 WeakPolarHBondContact O-CA 3.44Å; C6-F49 HydrophobicContact CB-CD1 3.94Å; C6-F49 HydrophobicContact CB-CE1 4.11Å; C6-F49 WeakPolarHBondContact SG-CE1 3.12Å; Q37-F49 CarbonylContact C-O 3.5Å; Q37-F49 VanDerWaalsContact CA-O 3.22Å; Q37-F49 WeakPolarHBondContact CA-O 3.35Å; L38-F49 HydrophobicContact CB-CB 4.37Å; L38-F49 PolarHBondContact N-O 3.22Å; L38-F49 PolarHBondContact O-N 3.46Å; K40-F49 HydrophobicContact CB-CE2 4.08Å; K40-F49 HydrophobicContact CG-CD2 4.28Å; K40-F49 HydrophobicContact CG-CE2 3.82Å; C47-F49 HydrophobicContact CB-CD2 4.21Å; C47-F49 HydrophobicContact CB-CE2 3.47Å; C47-F49 VanDerWaalsContact CB-CE2 3.47Å; C47-F49 HydrophobicContact CB-CZ 3.81Å; F49-P64 HydrophobicContact CB-CB 4.23Å; F49-P64 HydrophobicContact CB-CG 3.53Å; F49-V72 HydrophobicContact CB-CG1 4.19Å; F49-V72 HydrophobicContact CD1-CG1 3.95Å; F49-V72 HydrophobicContact CD2-CB 4.47Å; F49-V72 HydrophobicContact CD2-CG1 4.03Å; F49-V72 HydrophobicContact CD2-CG2 4.48Å; F49-V72 HydrophobicContact CE1-CB 4.48Å; F49-V72 HydrophobicContact CE1-CG1 4.32Å; F49-V72 HydrophobicContact CE2-CB 4.38Å; F49-V72 HydrophobicContact CE2-CG1 4.41Å; F49-V72 HydrophobicContact CE2-CG2 4.34Å; F49-V72 HydrophobicContact CG-CG1 3.79Å; F49-V72 HydrophobicContact CZ-CB 4.39Å; F49-L74 HydrophobicContact CB-CD1 4.07Å; F49-L74 HydrophobicContact CD1-CD1 3.95Å; F49-I122 HydrophobicContact CE1-CG2 4.47Å; F49-Y124 HydrophobicContact CZ-CD1 4.24Å; F49-Y124 HydrophobicContact CZ-CD2 4.41Å; F49-Y124 AromaticContact CZ-CG 3.82Å; F49-Y124 HydrophobicContact CZ-CG 3.82Å; F49-L131 HydrophobicContact CE1-CD1 4.21Å
50S98.1Very high93.2Very high0 Ų033.4 Ų33.40%019%0.192CC..EExtended strand (participates in β ladder)trans-131.9122.4180-158.90000109.4I4 C5 Q37 H52I4-S50 CarbonylContact C-O 3.45Å; C5-S50 PolarHBondContact N-O 2.82Å; C5-S50 PolarHBondContact O-N 3.3Å; Q37-S50 WeakPolarHBondContact CG-OG 3.31Å; Q37-S50 PolarHBondContact NE2-OG 2.97Å; S50-H52 PolarHBondContact OG-NE2 3.38Å
51G98.2Very high93.3Very high0 Ų032.2 Ų32.20%019%0.189CC..EExtended strand (participates in β ladder)trans-123.9133.4179.700000111.3G3 S35 K36 Q63G3-G51 CarbonylContact O-C 3.56Å; S35-G51 WeakPolarHBondContact CA-O 3.28Å; K36-G51 PolarHBondContact N-O 3.49Å; K36-G51 PolarHBondContact O-N 2.94Å; G51-Q63 CarbonylContact C-O 3.44Å; G51-Q63 VanDerWaalsContact CA-O 3.29Å; G51-Q63 WeakPolarHBondContact CA-O 3.09Å
52H98.2Very high93.5Very high0 Ų031.4 Ų31.40%018%0.181CC..EExtended strand (participates in β ladder)trans-132.5117-177.6-54-86.7000108.4C2 G3 L24 L27 K28 G31 S34 S35 S50C2-H52 CarbonylContact C-O 3.58Å; C2-H52 WeakPolarHBondContact CA-O 3.5Å; C2-H52 WeakPolarHBondContact CB-O 3.41Å; G3-H52 PolarHBondContact N-O 3.29Å; G3-H52 PolarHBondContact O-CD2 2.77Å; G3-H52 PolarHBondContact O-N 2.94Å; L24-H52 VanDerWaalsContact CD1-CE1 3.47Å; L24-H52 WeakPolarHBondContact CD1-CE1 3.4Å; L27-H52 WeakPolarHBondContact CB-CD2 3.49Å; L27-H52 WeakPolarHBondContact O-CB 3.38Å; K28-H52 WeakPolarHBondContact CG-ND1 3.29Å; G31-H52 WeakPolarHBondContact CA-O 3.39Å; S34-H52 CarbonylContact O-C 3.54Å; S34-H52 VanDerWaalsContact O-CA 3.24Å; S34-H52 WeakPolarHBondContact O-CA 3.18Å; S35-H52 PolarHBondContact OG-CE1 2.9Å; S35-H52 PolarHBondContact OG-ND1 3.28Å; S50-H52 PolarHBondContact OG-NE2 3.38Å
53V97.9Very high93.9Very high7 Ų729.4 Ų29.44%0.04217%0.17CC..EExtended strand (participates in β ladder)trans-102.6127.2-163.2-179.40000111.3G31 N33 S34 L60 T61 Q63G31-V53 CarbonylContact C-O 3.59Å; G31-V53 WeakPolarHBondContact CA-O 3.38Å; G31-V53 PolarHBondContact O-N 2.76Å; N33-V53 WeakPolarHBondContact CA-O 3.44Å; N33-V53 VanDerWaalsContact CB-O 3.28Å; N33-V53 WeakPolarHBondContact CB-O 3.49Å; N33-V53 PolarHBondContact N-O 2.71Å; S34-V53 PolarHBondContact N-O 3.45Å; S34-V53 PolarHBondContact O-N 3.39Å; V53-L60 HydrophobicContact CB-CD1 4.45Å; V53-L60 HydrophobicContact CG1-CD1 3.9Å; V53-T61 WeakPolarHBondContact CG2-O 3.24Å; V53-Q63 HydrophobicContact CG2-CB 4.17Å; V53-Q63 HydrophobicContact CG2-CG 4.05Å
54L96.4Very high94.5Very high5 Ų523 Ų233%0.02613%0.131CC..  trans-97.8113.7158.1176.769.3000107.3M1 R30 P32 L56 K488 G545 E547M1-L54 HydrophobicContact CB-CD2 4.29Å; M1-L54 VanDerWaalsContact O-CB 3.31Å; M1-L54 WeakPolarHBondContact O-CB 3.22Å; M1-L54 PolarHBondContact O-N 3.34Å; R30-L54 WeakPolarHBondContact O-CB 3.47Å; P32-L54 HydrophobicContact CG-CD1 4.32Å; L54-L56 HydrophobicContact CD2-CD1 4.18Å; L54-L56 HydrophobicContact CD2-CD2 4.19Å; L54-L56 HydrophobicContact CD2-CG 4.33Å; L54-L56 HydrophobicContact CG-CD1 4.44Å; L54-L56 HydrophobicContact CG-CD2 4.13Å; L54-L56 HydrophobicContact CG-CG 4.13Å; L54-L56 PolarHBondContact O-N 2.94Å; L54-K488 HydrophobicContact CD1-CD 3.94Å; L54-K488 HydrophobicContact CD1-CG 4.3Å; L54-G545 WeakPolarHBondContact CD1-O 3.45Å; L54-G545 VanDerWaalsContact CD2-O 3.31Å; L54-G545 WeakPolarHBondContact CD2-O 2.98Å; L54-E547 HydrophobicContact CD2-CB 4.29Å
55H94.4Very high95Very high37 Ų3720.4 Ų20.417%0.17112%0.118CC..  trans-81.1118.9-175.4177.9-127.9000111.5N33 R57 G58 L60 K488N33-H55 HydrophobicContact CB-CB 4.22Å; N33-H55 PolarHBondContact OD1-N 3.25Å; H55-R57 PolarHBondContact CD2-O 3.29Å; H55-R57 PolarHBondContact NE2-O 3.48Å; H55-G58 PolarHBondContact CE1-O 3.41Å; H55-G58 PolarHBondContact NE2-O 3.32Å; H55-L60 HydrophobicContact CB-CD1 3.8Å; H55-K488 PolarHBondContact O-NZ 3.03Å
56L91.5Very high95.3Very high4 Ų424 Ų242%0.02114%0.135CC..  trans-131.9-12.5-173.8-63.4176.8000114.6M1 L54 E78 C300 P302 K488 V489 E547M1-L56 HydrophobicContact CB-CD1 4.5Å; L54-L56 HydrophobicContact CD2-CD1 4.18Å; L54-L56 HydrophobicContact CD2-CD2 4.19Å; L54-L56 HydrophobicContact CD2-CG 4.33Å; L54-L56 HydrophobicContact CG-CD1 4.44Å; L54-L56 HydrophobicContact CG-CD2 4.13Å; L54-L56 HydrophobicContact CG-CG 4.13Å; L54-L56 PolarHBondContact O-N 2.94Å; L56-E78 WeakPolarHBondContact CB-OE1 3.28Å; L56-C300 VanDerWaalsContact O-O 3.09Å; L56-P302 VanDerWaalsContact O-CD 3.26Å; L56-P302 WeakPolarHBondContact O-CD 3.06Å; L56-K488 HydrophobicContact CD2-CB 3.74Å; L56-K488 HydrophobicContact CD2-CD 4.18Å; L56-V489 HydrophobicContact CD2-CG2 4.15Å; L56-E547 HydrophobicContact CD1-CB 3.59Å; L56-E547 HydrophobicContact CD1-CG 4.02Å; L56-E547 WeakPolarHBondContact CD1-OE1 3.49Å; L56-E547 WeakPolarHBondContact CD1-OE2 3.13Å
57R90.6Very high95.5Very high11 Ų1123.2 Ų23.24%0.04213%0.132CC..SBendtrans-160.4156.9175.966.3176.6-64.8164.56.6112.5H55 E78 I79 V85 E86 E89 N90H55-R57 PolarHBondContact CD2-O 3.29Å; H55-R57 PolarHBondContact NE2-O 3.48Å; R57-E78 VanDerWaalsContact CD-OE2 3.32Å; R57-E78 WeakPolarHBondContact CD-OE2 3.45Å; R57-I79 PolarHBondContact NH1-O 3.29Å; R57-V85 PolarHBondContact NH2-O 3.23Å; R57-E86 PolarHBondContact NH2-O 2.79Å; R57-E89 PolarHBondContact NE-O 3.04Å; R57-N90 PolarHBondContact O-ND2 3.35Å
58G90.1Very high95.5Very high22 Ų2233 Ų3323%0.22718%0.177CC..SBendtrans52.8-153179.400000114.3H55 E88H55-G58 PolarHBondContact CE1-O 3.41Å; H55-G58 PolarHBondContact NE2-O 3.32Å; G58-E88 WeakPolarHBondContact CA-O 3.28Å
59V90.9Very high95.5Very high114 Ų11440 Ų4069%0.69120%0.203SC*.SBendtrans-74.4141.3174.3-178.30000110.2T61 N90V59-T61 PolarHBondContact O-N 3.05Å; V59-T61 PolarHBondContact O-OG1 2.91Å; V59-N90 PolarHBondContact O-ND2 2.88Å
60L93.4Very high95.4Very high76 Ų7640.4 Ų40.440%0.39821%0.208SC..  trans-55.3108.4173.4172.365.5000109.7N33 V53 H55N33-L60 HydrophobicContact CB-CD1 4.21Å; V53-L60 HydrophobicContact CB-CD1 4.45Å; V53-L60 HydrophobicContact CG1-CD1 3.9Å; H55-L60 HydrophobicContact CB-CD1 3.8Å
61T94.5Very high95.4Very high20 Ų2040.8 Ų40.812%0.12321%0.21CC..  trans-105.4111.9-177.9-600000109V53 V59 V65 N90V53-T61 WeakPolarHBondContact CG2-O 3.24Å; V59-T61 PolarHBondContact O-N 3.05Å; V59-T61 PolarHBondContact O-OG1 2.91Å; T61-V65 HydrophobicContact CG2-CG1 3.96Å; T61-N90 WeakPolarHBondContact OG1-CB 3.31Å; T61-N90 PolarHBondContact OG1-OD1 3.44Å
62T96Very high95.4Very high62 Ų6240.9 Ų40.938%0.3821%0.211SC..  trans-70.7138.5179.464.40000110.8S34 V65S34-T62 VanDerWaalsContact OG-CG2 3.31Å; S34-T62 WeakPolarHBondContact OG-CG2 3.43Å; T62-V65 WeakPolarHBondContact O-CG1 3.39Å
63Q96.7Very high95.4Very high2 Ų240.9 Ų40.91%0.00921%0.211CC..SBendtrans-120.3147.7176.9-59.4-174.435.300110.7C2 K36 G51 V53 L74 W75 T92C2-Q63 PolarHBondContact SG-NE2 2.75Å; C2-Q63 VanDerWaalsContact SG-NE2 3.41Å; K36-Q63 WeakPolarHBondContact CB-O 3.21Å; G51-Q63 CarbonylContact C-O 3.44Å; G51-Q63 VanDerWaalsContact CA-O 3.29Å; G51-Q63 WeakPolarHBondContact CA-O 3.09Å; V53-Q63 HydrophobicContact CG2-CB 4.17Å; V53-Q63 HydrophobicContact CG2-CG 4.05Å; Q63-L74 HydrophobicContact CB-CD2 4.14Å; Q63-W75 PolarHBondContact NE2-O 2.85Å; Q63-W75 PolarHBondContact OE1-O 3.38Å; Q63-W75 VanDerWaalsContact OE1-O 3.11Å; Q63-T92 HydrophobicContact CG-CG2 4.1Å; Q63-T92 PolarHBondContact NE2-OG1 3.33Å
64P97.8Very high95.4Very high0 Ų040.5 Ų40.50%021%0.209CC..SBendcis-68.7143.34.8-13.525.8000113.3K36 L38 F49 V72 F73 L74K36-P64 PolarHBondContact NZ-O 3.34Å; K36-P64 WeakPolarHBondContact O-CD 3.33Å; L38-P64 HydrophobicContact CB-CB 4.44Å; L38-P64 HydrophobicContact CB-CG 4Å; L38-P64 HydrophobicContact CD2-CB 4.42Å; F49-P64 HydrophobicContact CB-CB 4.23Å; F49-P64 HydrophobicContact CB-CG 3.53Å; P64-V72 HydrophobicContact CB-CG1 3.56Å; P64-V72 HydrophobicContact CG-CG1 4.46Å; P64-F73 WeakPolarHBondContact CA-O 3.49Å; P64-L74 HydrophobicContact CB-CD2 4.12Å; P64-L74 HydrophobicContact CB-CG 4.12Å; P64-L74 HydrophobicContact CG-CD2 3.92Å; P64-L74 HydrophobicContact CG-CG 4.21Å
65V97.6Very high95.5Very high13 Ų1340.4 Ų40.48%0.07921%0.208CC..EExtended strand (participates in β ladder)trans-90.1145.3168.1-61.50000109.2T61 T62 V72 F73 T92 F96T61-V65 HydrophobicContact CG2-CG1 3.96Å; T62-V65 WeakPolarHBondContact O-CG1 3.39Å; V65-V72 WeakPolarHBondContact O-CA 3.41Å; V65-F73 HydrophobicContact CG2-CB 3.73Å; V65-F73 HydrophobicContact CG2-CD1 4.02Å; V65-F73 HydrophobicContact CG2-CG 4.38Å; V65-F73 PolarHBondContact N-O 3.16Å; V65-F73 PolarHBondContact O-N 3.02Å; V65-T92 HydrophobicContact CG1-CG2 4.36Å; V65-T92 HydrophobicContact CG2-CG2 4.41Å; V65-F96 HydrophobicContact CB-CD1 4.12Å; V65-F96 HydrophobicContact CB-CE1 4.22Å; V65-F96 HydrophobicContact CG2-CB 4.13Å; V65-F96 HydrophobicContact CG2-CD1 3.49Å; V65-F96 VanDerWaalsContact CG2-CD1 3.49Å; V65-F96 HydrophobicContact CG2-CD2 4.19Å; V65-F96 HydrophobicContact CG2-CE1 3.83Å; V65-F96 HydrophobicContact CG2-CE2 4.47Å; V65-F96 HydrophobicContact CG2-CG 3.68Å; V65-F96 HydrophobicContact CG2-CZ 4.31Å
66E97.8Very high95.7Very high79 Ų7938.6 Ų38.637%0.36920%0.2SC..EExtended strand (participates in β ladder)trans-135.1138.6-176.8-178.6-179.117500109.7L38 K40 N71 V72L38-E66 WeakPolarHBondContact CD1-OE2 3.24Å; L38-E66 HydrophobicContact CD2-CB 4.19Å; L38-E66 HydrophobicContact CD2-CG 4.5Å; L38-E66 VanDerWaalsContact CD2-OE2 3.31Å; L38-E66 WeakPolarHBondContact CD2-OE2 3.25Å; K40-E66 WeakPolarHBondContact CE-OE1 3.41Å; K40-E66 IonicContact NZ-OE1 2.78Å; K40-E66 PolarHBondContact NZ-OE1 3.03Å; K40-E66 IonicContact NZ-OE2 3.24Å; E66-N71 VanDerWaalsContact CA-O 3.24Å; E66-N71 WeakPolarHBondContact CA-O 3.46Å; E66-V72 HydrophobicContact CG-CG2 4.45Å
67D96.1Very high95.9Very high27 Ų2738.5 Ų38.514%0.14420%0.2CC..  trans-98.8170.9173.775.49.4000112.3R69 G70 N71 F96 S100D67-R69 PolarHBondContact O-N 2.85Å; D67-R69 VanDerWaalsContact O-N 3.08Å; D67-R69 WeakPolarHBondContact OD1-CA 3.47Å; D67-R69 WeakPolarHBondContact OD1-CB 3.32Å; D67-R69 PolarHBondContact OD1-N 2.76Å; D67-R69 IonicContact OD2-CZ 3.15Å; D67-R69 IonicContact OD2-NE 2.59Å; D67-R69 PolarHBondContact OD2-NE 3.31Å; D67-R69 IonicContact OD2-NH2 2.82Å; D67-R69 PolarHBondContact OD2-NH2 3.08Å; D67-G70 PolarHBondContact O-N 3.48Å; D67-G70 PolarHBondContact OD1-N 2.96Å; D67-N71 PolarHBondContact N-O 3.22Å; D67-N71 VanDerWaalsContact N-O 3.13Å; D67-N71 WeakPolarHBondContact OD1-CB 3.3Å; D67-N71 PolarHBondContact OD1-N 3.07Å; D67-N71 PolarHBondContact OD1-ND2 2.97Å; D67-N71 PolarHBondContact OD2-ND2 2.82Å; D67-F96 HydrophobicContact CB-CE1 3.84Å; D67-F96 HydrophobicContact CB-CZ 3.77Å; D67-S100 PolarHBondContact OD2-OG 2.84Å
68E95.4Very high96.1Very high205 Ų20538.4 Ų38.496%0.95820%0.199SC*.THydrogen-bonded Turntrans-62.2-17.8-178.8-61.4179.5173.200113.9G70E68-G70 VanDerWaalsContact C-N 3.3Å
69R95.4Very high96.4Very high154 Ų15437.5 Ų37.558%0.58119%0.19SC*.THydrogen-bonded Turntrans-89.30.6176-63.1172.5-63.5-126.9-2.1112.1D67 N71 S100 A126D67-R69 PolarHBondContact O-N 2.85Å; D67-R69 VanDerWaalsContact O-N 3.08Å; D67-R69 WeakPolarHBondContact OD1-CA 3.47Å; D67-R69 WeakPolarHBondContact OD1-CB 3.32Å; D67-R69 PolarHBondContact OD1-N 2.76Å; D67-R69 IonicContact OD2-CZ 3.15Å; D67-R69 IonicContact OD2-NE 2.59Å; D67-R69 PolarHBondContact OD2-NE 3.31Å; D67-R69 IonicContact OD2-NH2 2.82Å; D67-R69 PolarHBondContact OD2-NH2 3.08Å; R69-N71 VanDerWaalsContact C-N 3.33Å; R69-S100 PolarHBondContact NH1-O 2.84Å; R69-S100 PolarHBondContact NH2-O 2.87Å; R69-A126 WeakPolarHBondContact O-CB 3.24Å
70G96.1Very high96.6Very high11 Ų1133.6 Ų33.611%0.11316%0.163CC..  trans80.111.5-18000000114.2D67 E68D67-G70 PolarHBondContact O-N 3.48Å; D67-G70 PolarHBondContact OD1-N 2.96Å; E68-G70 VanDerWaalsContact C-N 3.3Å
71N97.6Very high96.7Very high8 Ų831.6 Ų31.64%0.04316%0.156CC..  trans-67.8142.1172.6-58.6-44.1000109.3E66 D67 R69 F96 Y123 Y124 Q125 A126E66-N71 VanDerWaalsContact CA-O 3.24Å; E66-N71 WeakPolarHBondContact CA-O 3.46Å; D67-N71 PolarHBondContact N-O 3.22Å; D67-N71 VanDerWaalsContact N-O 3.13Å; D67-N71 WeakPolarHBondContact OD1-CB 3.3Å; D67-N71 PolarHBondContact OD1-N 3.07Å; D67-N71 PolarHBondContact OD1-ND2 2.97Å; D67-N71 PolarHBondContact OD2-ND2 2.82Å; R69-N71 VanDerWaalsContact C-N 3.33Å; N71-F96 HydrophobicContact CB-CE2 4.45Å; N71-F96 HydrophobicContact CB-CZ 4.47Å; N71-Y123 HydrophobicContact CB-CE2 3.92Å; N71-Y124 CarbonylContact C-O 3.56Å; N71-Y124 WeakPolarHBondContact CA-O 3.32Å; N71-Y124 WeakPolarHBondContact CB-O 3.44Å; N71-Q125 WeakPolarHBondContact OD1-CA 3.48Å; N71-A126 PolarHBondContact OD1-N 3.42Å
72V98.5Very high96.7Very high1 Ų132.8 Ų32.81%0.00617%0.172CC..EExtended strand (participates in β ladder)trans-122.4134.8-176.8-178.30000109.8L38 K40 F49 P64 V65 E66 Y123 Y124L38-V72 HydrophobicContact CD2-CB 4.37Å; L38-V72 HydrophobicContact CD2-CG1 3.85Å; L38-V72 HydrophobicContact CD2-CG2 3.55Å; K40-V72 HydrophobicContact CG-CG2 4.19Å; F49-V72 HydrophobicContact CB-CG1 4.19Å; F49-V72 HydrophobicContact CD1-CG1 3.95Å; F49-V72 HydrophobicContact CD2-CB 4.47Å; F49-V72 HydrophobicContact CD2-CG1 4.03Å; F49-V72 HydrophobicContact CD2-CG2 4.48Å; F49-V72 HydrophobicContact CE1-CB 4.48Å; F49-V72 HydrophobicContact CE1-CG1 4.32Å; F49-V72 HydrophobicContact CE2-CB 4.38Å; F49-V72 HydrophobicContact CE2-CG1 4.41Å; F49-V72 HydrophobicContact CE2-CG2 4.34Å; F49-V72 HydrophobicContact CG-CG1 3.79Å; F49-V72 HydrophobicContact CZ-CB 4.39Å; P64-V72 HydrophobicContact CB-CG1 3.56Å; P64-V72 HydrophobicContact CG-CG1 4.46Å; V65-V72 WeakPolarHBondContact O-CA 3.41Å; E66-V72 HydrophobicContact CG-CG2 4.45Å; V72-Y123 CarbonylContact O-C 3.58Å; V72-Y123 WeakPolarHBondContact O-CA 3.45Å; V72-Y123 WeakPolarHBondContact O-CD2 3.43Å; V72-Y124 HydrophobicContact CB-CD1 4.43Å; V72-Y124 HydrophobicContact CG2-CD1 4.19Å; V72-Y124 PolarHBondContact N-O 3.23Å; V72-Y124 PolarHBondContact O-N 3.35Å
73F98.6Very high96.6Very high0 Ų030.5 Ų30.50%016%0.157CC..EExtended strand (participates in β ladder)trans-130.8138.3179.1-177.2-120.2000112.8P64 V65 W75 T92 L95 F96 L99 F121 Y123P64-F73 WeakPolarHBondContact CA-O 3.49Å; V65-F73 HydrophobicContact CG2-CB 3.73Å; V65-F73 HydrophobicContact CG2-CD1 4.02Å; V65-F73 HydrophobicContact CG2-CG 4.38Å; V65-F73 PolarHBondContact N-O 3.16Å; V65-F73 PolarHBondContact O-N 3.02Å; F73-W75 HydrophobicContact CD1-CB 4.4Å; F73-W75 HydrophobicContact CE1-CB 3.69Å; F73-W75 HydrophobicContact CE1-CE3 4.44Å; F73-W75 HydrophobicContact CE1-CG 4.32Å; F73-W75 HydrophobicContact CZ-CB 3.93Å; F73-W75 HydrophobicContact CZ-CD2 4.25Å; F73-W75 AromaticContact CZ-CE3 3.71Å; F73-W75 HydrophobicContact CZ-CE3 3.71Å; F73-W75 HydrophobicContact CZ-CG 4.39Å; F73-T92 HydrophobicContact CD1-CG2 4.18Å; F73-T92 HydrophobicContact CE1-CG2 4.22Å; F73-L95 HydrophobicContact CE1-CB 4.49Å; F73-L95 HydrophobicContact CE1-CD2 4.27Å; F73-L95 HydrophobicContact CE1-CG 4.37Å; F73-L95 HydrophobicContact CZ-CD2 3.72Å; F73-L95 HydrophobicContact CZ-CG 4.09Å; F73-F96 HydrophobicContact CB-CD2 3.27Å; F73-F96 HydrophobicContact CB-CE2 3.46Å; F73-F96 VanDerWaalsContact CB-CE2 3.46Å; F73-F96 HydrophobicContact CB-CG 4.03Å; F73-F96 HydrophobicContact CB-CZ 4.35Å; F73-F96 HydrophobicContact CD1-CB 3.78Å; F73-F96 AromaticContact CD1-CD2 3.98Å; F73-F96 HydrophobicContact CD1-CD2 3.98Å; F73-F96 HydrophobicContact CD1-CG 4.14Å; F73-F96 HydrophobicContact CE1-CB 4.34Å; F73-F96 HydrophobicContact CG-CB 4.47Å; F73-F96 AromaticContact CG-CD2 3.79Å; F73-F96 HydrophobicContact CG-CD2 3.79Å; F73-F96 HydrophobicContact CG-CE2 4.43Å; F73-F96 HydrophobicContact CG-CG 4.4Å; F73-L99 HydrophobicContact CD2-CD2 3.91Å; F73-L99 HydrophobicContact CE2-CD2 3.92Å; F73-F121 HydrophobicContact CE2-CB 3.83Å; F73-F121 AromaticContact CE2-CD2 3.91Å; F73-F121 HydrophobicContact CE2-CD2 3.91Å; F73-F121 HydrophobicContact CE2-CG 4.15Å; F73-F121 HydrophobicContact CZ-CB 4.31Å; F73-Y123 HydrophobicContact CB-CD2 4.16Å; F73-Y123 HydrophobicContact CD2-CD2 4.14Å; F73-Y123 HydrophobicContact CD2-CG 4.4Å
74L98.7Very high96.5Very high0 Ų037.1 Ų37.10%019%0.186CC..EExtended strand (participates in β ladder)trans-128.9125.1174.9-79.2160.3000108.4I4 C5 F49 Q63 P64 F121 I122I4-L74 HydrophobicContact CB-CB 4.06Å; I4-L74 HydrophobicContact CB-CD2 4.12Å; I4-L74 HydrophobicContact CB-CG 4.5Å; I4-L74 HydrophobicContact CG2-CB 3.96Å; I4-L74 HydrophobicContact CG2-CD2 3.87Å; C5-L74 WeakPolarHBondContact O-CD1 3.47Å; F49-L74 HydrophobicContact CB-CD1 4.07Å; F49-L74 HydrophobicContact CD1-CD1 3.95Å; Q63-L74 HydrophobicContact CB-CD2 4.14Å; P64-L74 HydrophobicContact CB-CD2 4.12Å; P64-L74 HydrophobicContact CB-CG 4.12Å; P64-L74 HydrophobicContact CG-CD2 3.92Å; P64-L74 HydrophobicContact CG-CG 4.21Å; L74-F121 CarbonylContact O-C 3.58Å; L74-F121 VanDerWaalsContact O-CA 3.24Å; L74-F121 WeakPolarHBondContact O-CA 3.25Å; L74-F121 WeakPolarHBondContact O-CB 3.42Å; L74-I122 HydrophobicContact CB-CB 4.18Å; L74-I122 HydrophobicContact CD1-CB 4.38Å; L74-I122 HydrophobicContact CD1-CD1 4.27Å; L74-I122 PolarHBondContact N-O 2.61Å; L74-I122 PolarHBondContact O-N 3.09Å
75W98.2Very high96.2Very high2 Ų238.3 Ų38.31%0.00819%0.193CC..EExtended strand (participates in β ladder)trans-124.2119.2-176.4179.8-113.3000110.7Q63 F73 G77 I79 D91 T92 L95 F112 V115 W119 F121Q63-W75 PolarHBondContact NE2-O 2.85Å; Q63-W75 PolarHBondContact OE1-O 3.38Å; Q63-W75 VanDerWaalsContact OE1-O 3.11Å; F73-W75 HydrophobicContact CD1-CB 4.4Å; F73-W75 HydrophobicContact CE1-CB 3.69Å; F73-W75 HydrophobicContact CE1-CE3 4.44Å; F73-W75 HydrophobicContact CE1-CG 4.32Å; F73-W75 HydrophobicContact CZ-CB 3.93Å; F73-W75 HydrophobicContact CZ-CD2 4.25Å; F73-W75 AromaticContact CZ-CE3 3.71Å; F73-W75 HydrophobicContact CZ-CE3 3.71Å; F73-W75 HydrophobicContact CZ-CG 4.39Å; W75-G77 PolarHBondContact NE1-O 3.27Å; W75-I79 HydrophobicContact CH2-CG1 4.43Å; W75-I79 HydrophobicContact CZ2-CD1 4.14Å; W75-I79 HydrophobicContact CZ2-CG1 3.73Å; W75-D91 PolarHBondContact NE1-OD2 3.35Å; W75-T92 HydrophobicContact CB-CG2 3.84Å; W75-T92 VanDerWaalsContact CD1-OG1 3.29Å; W75-L95 HydrophobicContact CD2-CD2 4.04Å; W75-L95 HydrophobicContact CE3-CD2 3.56Å; W75-L95 HydrophobicContact CH2-CD2 3.52Å; W75-L95 HydrophobicContact CZ2-CD2 4.04Å; W75-L95 HydrophobicContact CZ3-CD2 3.29Å; W75-F112 HydrophobicContact CZ3-CE1 4.17Å; W75-V115 HydrophobicContact CH2-CG1 4.26Å; W75-W119 HydrophobicContact CE3-CB 4.32Å; W75-W119 HydrophobicContact CH2-CB 3.05Å; W75-W119 AromaticContact CH2-CD1 3.79Å; W75-W119 HydrophobicContact CH2-CD2 4.1Å; W75-W119 AromaticContact CH2-CG 3.37Å; W75-W119 HydrophobicContact CH2-CG 3.37Å; W75-W119 HydrophobicContact CZ2-CB 3.54Å; W75-W119 HydrophobicContact CZ2-CG 4.2Å; W75-W119 HydrophobicContact CZ3-CB 3.49Å; W75-W119 VanDerWaalsContact CZ3-CB 3.49Å; W75-W119 HydrophobicContact CZ3-CD2 4.22Å; W75-W119 HydrophobicContact CZ3-CE3 4.38Å; W75-W119 AromaticContact CZ3-CG 3.87Å; W75-W119 HydrophobicContact CZ3-CG 3.87Å; W75-F121 HydrophobicContact CE3-CB 3.84Å; W75-F121 HydrophobicContact CZ3-CB 4.2Å
76N97.9Very high95.9Very high0 Ų042.1 Ų42.10%021%0.21CC..EExtended strand (participates in β ladder)trans-114.285166172.231000108.1M1 C2 I4 R30 W119 S120 R141M1-N76 WeakPolarHBondContact CA-OD1 3.14Å; M1-N76 WeakPolarHBondContact CG-OD1 3.26Å; C2-N76 HydrophobicContact CB-CB 4.3Å; C2-N76 PolarHBondContact N-OD1 3Å; C2-N76 PolarHBondContact O-OD1 3.41Å; I4-N76 HydrophobicContact CD1-CB 3.86Å; I4-N76 HydrophobicContact CG1-CB 4.05Å; I4-N76 HydrophobicContact CG2-CB 4.12Å; R30-N76 PolarHBondContact NH2-ND2 3.38Å; N76-W119 CarbonylContact O-C 3.52Å; N76-W119 WeakPolarHBondContact O-CA 3.37Å; N76-S120 CarbonylContact C-O 3.57Å; N76-S120 PolarHBondContact N-O 3.44Å; N76-S120 PolarHBondContact ND2-OG 3.48Å; N76-S120 PolarHBondContact O-N 2.61Å; N76-R141 VanDerWaalsContact O-CG 3.3Å; N76-R141 WeakPolarHBondContact O-CG 3.42Å
77G95.8Very high95.2Very high2 Ų241.3 Ų41.32%0.02122%0.217CC..EExtended strand (participates in β ladder)trans-166.2-174.7-179.300000114.1W75 P118W75-G77 PolarHBondContact NE1-O 3.27Å; G77-P118 CarbonylContact C-O 3.59Å; G77-P118 WeakPolarHBondContact CA-O 3.21Å
78E95.3Very high94.8Very high8 Ų848.1 Ų48.14%0.03725%0.248CC..  trans-141.8135169.2-70.2-68.3149.700108.9L56 R57 F80 D91 G117 P118 E547 R549L56-E78 WeakPolarHBondContact CB-OE1 3.28Å; R57-E78 VanDerWaalsContact CD-OE2 3.32Å; R57-E78 WeakPolarHBondContact CD-OE2 3.45Å; E78-F80 HydrophobicContact CB-CE1 4.17Å; E78-F80 HydrophobicContact CB-CE2 4.08Å; E78-F80 HydrophobicContact CB-CZ 3.78Å; E78-F80 HydrophobicContact CG-CZ 4.32Å; E78-D91 VanDerWaalsContact CA-OD2 3.24Å; E78-D91 WeakPolarHBondContact CA-OD2 3.45Å; E78-G117 WeakPolarHBondContact O-CA 3.42Å; E78-P118 HydrophobicContact CB-CG 4.39Å; E78-P118 PolarHBondContact N-O 2.99Å; E78-P118 WeakPolarHBondContact O-CD 3.45Å; E78-E547 WeakPolarHBondContact CG-OE1 3.46Å; E78-E547 WeakPolarHBondContact CG-OE2 3.46Å; E78-R549 IonicContact OE2-NH2 3.44Å
79I96.3Very high94.6Very high4 Ų441.8 Ų41.82%0.02122%0.218CC..  trans-99.4113.6174.2-55-175.2000109.6R57 W75 I83 V85 D91 L95 V115R57-I79 PolarHBondContact NH1-O 3.29Å; W75-I79 HydrophobicContact CH2-CG1 4.43Å; W75-I79 HydrophobicContact CZ2-CD1 4.14Å; W75-I79 HydrophobicContact CZ2-CG1 3.73Å; I79-I83 HydrophobicContact CD1-CD1 3.47Å; I79-I83 VanDerWaalsContact CD1-CD1 3.47Å; I79-I83 HydrophobicContact CD1-CG1 3.85Å; I79-I83 HydrophobicContact CG2-CD1 4.47Å; I79-I83 HydrophobicContact CG2-CG1 3.67Å; I79-V85 HydrophobicContact CB-CG2 4.07Å; I79-V85 HydrophobicContact CD1-CG2 4.3Å; I79-V85 HydrophobicContact CG2-CG2 3.87Å; I79-D91 HydrophobicContact CB-CB 4.09Å; I79-D91 HydrophobicContact CD1-CB 4.02Å; I79-D91 HydrophobicContact CG1-CB 3.91Å; I79-D91 PolarHBondContact N-OD2 2.79Å; I79-L95 HydrophobicContact CD1-CB 4.18Å; I79-L95 HydrophobicContact CD1-CD2 4.27Å; I79-V115 HydrophobicContact CD1-CG1 4.13Å; I79-V115 HydrophobicContact CD1-CG2 4.46Å; I79-V115 HydrophobicContact CG1-CG1 3.91Å; I79-V115 HydrophobicContact CG2-CG1 4.41Å
80F95.6Very high94.5Very high31 Ų3135.5 Ų35.514%0.13620%0.196CC..  trans-101-22.1-179.9-66.9-53.2000113.5E78 Q116 P118 K296 R297 R549E78-F80 HydrophobicContact CB-CE1 4.17Å; E78-F80 HydrophobicContact CB-CE2 4.08Å; E78-F80 HydrophobicContact CB-CZ 3.78Å; E78-F80 HydrophobicContact CG-CZ 4.32Å; F80-Q116 PolarHBondContact N-O 3.07Å; F80-P118 VanDerWaalsContact CE2-CD 3.46Å; F80-P118 HydrophobicContact CE2-CG 4.06Å; F80-K296 HydrophobicContact CB-CB 4.28Å; F80-K296 HydrophobicContact CB-CD 4.35Å; F80-K296 HydrophobicContact CD1-CB 4.29Å; F80-K296 WeakPolarHBondContact CD1-O 3.35Å; F80-K296 WeakPolarHBondContact CE1-O 3.35Å; F80-K296 HydrophobicContact CG-CB 4.44Å; F80-R297 HydrophobicContact CD2-CG 4.46Å; F80-R297 HydrophobicContact CE1-CG 4.34Å; F80-R297 HydrophobicContact CE2-CG 3.94Å; F80-R297 HydrophobicContact CZ-CG 3.89Å; F80-R549 HydrophobicContact CZ-CG 4.49Å
81S94.9Very high94.4Very high35 Ų3535.1 Ų35.125%0.24519%0.192CC..BIsolated β-bridgetrans-166.7178.5-175.5-175.60000110.1I83 Q116S81-I83 PolarHBondContact O-N 3.05Å; S81-Q116 PolarHBondContact N-O 3.37Å; S81-Q116 WeakPolarHBondContact O-CB 3.39Å; S81-Q116 PolarHBondContact O-N 2.84Å; S81-Q116 PolarHBondContact OG-OE1 2.89Å
82G94.5Very high94.4Very high44 Ų4435 Ų3545%0.45419%0.191SC..SBendtrans89.2-77.4178.900000112.4E114G82-E114 WeakPolarHBondContact CA-O 3.31Å
83I94.3Very high94.2Very high14 Ų1438.4 Ų38.47%0.07221%0.207CC..SBendtrans-89.2148.8170.774.4167.8000111.1I79 S81 V85 L95 Y98 L111 E114 V115I79-I83 HydrophobicContact CD1-CD1 3.47Å; I79-I83 VanDerWaalsContact CD1-CD1 3.47Å; I79-I83 HydrophobicContact CD1-CG1 3.85Å; I79-I83 HydrophobicContact CG2-CD1 4.47Å; I79-I83 HydrophobicContact CG2-CG1 3.67Å; S81-I83 PolarHBondContact O-N 3.05Å; I83-V85 HydrophobicContact CD1-CG2 4.45Å; I83-V85 HydrophobicContact CG1-CG2 4.14Å; I83-V85 PolarHBondContact O-N 2.98Å; I83-L95 HydrophobicContact CD1-CD1 4Å; I83-Y98 HydrophobicContact CD1-CD2 4.28Å; I83-Y98 HydrophobicContact CD1-CE2 4.49Å; I83-L111 HydrophobicContact CG2-CD1 4.08Å; I83-E114 HydrophobicContact CG2-CB 3.91Å; I83-V115 HydrophobicContact CD1-CG2 4.13Å; I83-V115 HydrophobicContact CG1-CG2 4.3Å; I83-V115 HydrophobicContact CG2-CG2 4.11Å
84K93.3Very high94.1Very high141 Ų14139.7 Ų39.761%0.61321%0.213SC*.  trans-75.2118.5-178.2-172.7177.5177.5-174.20110.8E86K84-E86 WeakPolarHBondContact CE-OE1 3.42Å; K84-E86 IonicContact NZ-OE1 3.41Å; K84-E86 PolarHBondContact NZ-OE1 2.89Å
85V92.6Very high94Very high25 Ų2539.7 Ų39.715%0.15221%0.213CC..  trans-138.6113.1171.3-165.20000108.3R57 I79 I83 E89 D91 I94R57-V85 PolarHBondContact NH2-O 3.23Å; I79-V85 HydrophobicContact CB-CG2 4.07Å; I79-V85 HydrophobicContact CD1-CG2 4.3Å; I79-V85 HydrophobicContact CG2-CG2 3.87Å; I83-V85 HydrophobicContact CD1-CG2 4.45Å; I83-V85 HydrophobicContact CG1-CG2 4.14Å; I83-V85 PolarHBondContact O-N 2.98Å; V85-E89 HydrophobicContact CG1-CB 3.88Å; V85-D91 HydrophobicContact CG1-CB 4.13Å; V85-D91 HydrophobicContact CG2-CB 4.45Å; V85-I94 HydrophobicContact CG1-CG1 4.17Å; V85-I94 HydrophobicContact CG2-CB 4.5Å; V85-I94 HydrophobicContact CG2-CG2 4.12Å
86E90.8Very high94Very high94 Ų9439.9 Ų39.944%0.43921%0.214SC..  trans-67.9163.4-179.1-61.6-66.4168.600111.9R57 K84 E88 E89R57-E86 PolarHBondContact NH2-O 2.79Å; K84-E86 WeakPolarHBondContact CE-OE1 3.42Å; K84-E86 IonicContact NZ-OE1 3.41Å; K84-E86 PolarHBondContact NZ-OE1 2.89Å; E86-E88 VanDerWaalsContact C-N 3.29Å; E86-E88 PolarHBondContact O-N 2.82Å; E86-E89 HydrophobicContact CB-CB 4.38Å; E86-E89 HydrophobicContact CB-CG 3.92Å; E86-E89 WeakPolarHBondContact CB-OE2 3.45Å; E86-E89 PolarHBondContact N-OE2 3.36Å; E86-E89 PolarHBondContact O-N 2.78Å; E86-E89 VanDerWaalsContact O-N 3.08Å
87A84.3Confident93.9Very high62 Ų6243.7 Ų43.751%0.51223%0.234SC..THydrogen-bonded Turntrans-59.9-36.3-172.600000113.7
88E86.3Confident93.9Very high170 Ų17048.8 Ų48.879%0.79425%0.254SS*.THydrogen-bonded Turntrans-91.5-3.7179.9-63.9177.6-165.200113.1G58 E86G58-E88 WeakPolarHBondContact CA-O 3.28Å; E86-E88 VanDerWaalsContact C-N 3.29Å; E86-E88 PolarHBondContact O-N 2.82Å
89E91.7Very high94Very high72 Ų7248.4 Ų48.434%0.33625%0.252SS..SBendtrans-85.5149.8179.5-72.6-179.8147.100112R57 V85 E86 I94R57-E89 PolarHBondContact NE-O 3.04Å; V85-E89 HydrophobicContact CG1-CB 3.88Å; E86-E89 HydrophobicContact CB-CB 4.38Å; E86-E89 HydrophobicContact CB-CG 3.92Å; E86-E89 WeakPolarHBondContact CB-OE2 3.45Å; E86-E89 PolarHBondContact N-OE2 3.36Å; E86-E89 PolarHBondContact O-N 2.78Å; E86-E89 VanDerWaalsContact O-N 3.08Å; E89-I94 HydrophobicContact CB-CG1 4.18Å; E89-I94 HydrophobicContact CG-CD1 4.49Å
90N93.7Very high93.9Very high21 Ų2149 Ų4911%0.11226%0.257CS..  trans-92.5119.9171.8-171.1-83.2000110R57 V59 T61 T92 Q93 I94R57-N90 PolarHBondContact O-ND2 3.35Å; V59-N90 PolarHBondContact O-ND2 2.88Å; T61-N90 WeakPolarHBondContact OG1-CB 3.31Å; T61-N90 PolarHBondContact OG1-OD1 3.44Å; N90-T92 VanDerWaalsContact C-N 3.27Å; N90-T92 PolarHBondContact O-N 3.01Å; N90-T92 WeakPolarHBondContact OD1-CB 3.21Å; N90-T92 PolarHBondContact OD1-N 2.93Å; N90-T92 PolarHBondContact OD1-OG1 3.31Å; N90-Q93 PolarHBondContact O-N 3.41Å; N90-I94 WeakPolarHBondContact O-CG1 3.2Å; N90-I94 PolarHBondContact O-N 2.95Å
91D94.4Very high93.8Very high4 Ų451.6 Ų51.62%0.02128%0.278CS..Hα-helixtrans-62.3-30.3-177.264.1-23.9000113.7W75 E78 I79 V85 L95W75-D91 PolarHBondContact NE1-OD2 3.35Å; E78-D91 VanDerWaalsContact CA-OD2 3.24Å; E78-D91 WeakPolarHBondContact CA-OD2 3.45Å; I79-D91 HydrophobicContact CB-CB 4.09Å; I79-D91 HydrophobicContact CD1-CB 4.02Å; I79-D91 HydrophobicContact CG1-CB 3.91Å; I79-D91 PolarHBondContact N-OD2 2.79Å; V85-D91 HydrophobicContact CG1-CB 4.13Å; V85-D91 HydrophobicContact CG2-CB 4.45Å; D91-L95 VanDerWaalsContact O-CB 3.24Å; D91-L95 WeakPolarHBondContact O-CB 3.48Å; D91-L95 PolarHBondContact O-N 2.98Å
92T96.3Very high93.9Very high4 Ų451 Ų513%0.02528%0.275CS..Hα-helixtrans-61-47.5175.6-540000110.8Q63 V65 F73 W75 N90 F96Q63-T92 HydrophobicContact CG-CG2 4.1Å; Q63-T92 PolarHBondContact NE2-OG1 3.33Å; V65-T92 HydrophobicContact CG1-CG2 4.36Å; V65-T92 HydrophobicContact CG2-CG2 4.41Å; F73-T92 HydrophobicContact CD1-CG2 4.18Å; F73-T92 HydrophobicContact CE1-CG2 4.22Å; W75-T92 HydrophobicContact CB-CG2 3.84Å; W75-T92 VanDerWaalsContact CD1-OG1 3.29Å; N90-T92 VanDerWaalsContact C-N 3.27Å; N90-T92 PolarHBondContact O-N 3.01Å; N90-T92 WeakPolarHBondContact OD1-CB 3.21Å; N90-T92 PolarHBondContact OD1-N 2.93Å; N90-T92 PolarHBondContact OD1-OG1 3.31Å; T92-F96 VanDerWaalsContact O-CB 3.27Å; T92-F96 WeakPolarHBondContact O-CB 3.45Å; T92-F96 PolarHBondContact O-N 2.56Å
93Q95.5Very high93.8Very high74 Ų7457.8 Ų57.835%0.34629%0.291SS..Hα-helixtrans-69.4-42.9-178.3-172.162.857.800111.3N90 F96 N97N90-Q93 PolarHBondContact O-N 3.41Å; Q93-F96 PolarHBondContact O-N 2.87Å; Q93-N97 PolarHBondContact NE2-OD1 2.79Å; Q93-N97 PolarHBondContact O-N 2.84Å; Q93-N97 PolarHBondContact O-ND2 3.39Å; Q93-N97 PolarHBondContact O-OD1 2.84Å
94I96.1Very high93.8Very high27 Ų2760.5 Ų60.514%0.13831%0.306CS..Hα-helixtrans-62-48.9178.9-65-59.9000110.8V85 E89 N90 F96 N97 Y98V85-I94 HydrophobicContact CG1-CG1 4.17Å; V85-I94 HydrophobicContact CG2-CB 4.5Å; V85-I94 HydrophobicContact CG2-CG2 4.12Å; E89-I94 HydrophobicContact CB-CG1 4.18Å; E89-I94 HydrophobicContact CG-CD1 4.49Å; N90-I94 WeakPolarHBondContact O-CG1 3.2Å; N90-I94 PolarHBondContact O-N 2.95Å; I94-F96 VanDerWaalsContact C-N 3.34Å; I94-F96 PolarHBondContact O-N 3.11Å; I94-N97 PolarHBondContact O-N 2.93Å; I94-Y98 HydrophobicContact CG2-CD2 3.91Å; I94-Y98 HydrophobicContact CG2-CE2 3.55Å; I94-Y98 WeakPolarHBondContact O-CD2 3.28Å; I94-Y98 PolarHBondContact O-N 2.87Å
95L97.3Very high93.9Very high0 Ų056.2 Ų56.20%029%0.288CS..Hα-helixtrans-64-40.1178.6-177.760.4000111.7F73 W75 I79 I83 D91 N97 Y98 L99 L111 F112 V115F73-L95 HydrophobicContact CE1-CB 4.49Å; F73-L95 HydrophobicContact CE1-CD2 4.27Å; F73-L95 HydrophobicContact CE1-CG 4.37Å; F73-L95 HydrophobicContact CZ-CD2 3.72Å; F73-L95 HydrophobicContact CZ-CG 4.09Å; W75-L95 HydrophobicContact CD2-CD2 4.04Å; W75-L95 HydrophobicContact CE3-CD2 3.56Å; W75-L95 HydrophobicContact CH2-CD2 3.52Å; W75-L95 HydrophobicContact CZ2-CD2 4.04Å; W75-L95 HydrophobicContact CZ3-CD2 3.29Å; I79-L95 HydrophobicContact CD1-CB 4.18Å; I79-L95 HydrophobicContact CD1-CD2 4.27Å; I83-L95 HydrophobicContact CD1-CD1 4Å; D91-L95 VanDerWaalsContact O-CB 3.24Å; D91-L95 WeakPolarHBondContact O-CB 3.48Å; D91-L95 PolarHBondContact O-N 2.98Å; L95-N97 VanDerWaalsContact C-N 3.34Å; L95-N97 PolarHBondContact O-N 3.33Å; L95-Y98 PolarHBondContact O-N 2.78Å; L95-L99 VanDerWaalsContact O-CB 3.28Å; L95-L99 WeakPolarHBondContact O-CB 3.39Å; L95-L99 PolarHBondContact O-N 2.83Å; L95-L111 HydrophobicContact CD1-CD1 4.03Å; L95-L111 HydrophobicContact CD1-CD2 3.85Å; L95-L111 HydrophobicContact CD1-CG 3.92Å; L95-F112 HydrophobicContact CD2-CE1 4.27Å; L95-V115 HydrophobicContact CD1-CG2 4.17Å
96F97.4Very high94.1Very high5 Ų558 Ų582%0.02230%0.302CS..Hα-helixtrans-63.1-40176.9-172.4-132.7000112.1V65 D67 N71 F73 T92 Q93 I94 Y98 L99 S100 Y123V65-F96 HydrophobicContact CB-CD1 4.12Å; V65-F96 HydrophobicContact CB-CE1 4.22Å; V65-F96 HydrophobicContact CG2-CB 4.13Å; V65-F96 HydrophobicContact CG2-CD1 3.49Å; V65-F96 VanDerWaalsContact CG2-CD1 3.49Å; V65-F96 HydrophobicContact CG2-CD2 4.19Å; V65-F96 HydrophobicContact CG2-CE1 3.83Å; V65-F96 HydrophobicContact CG2-CE2 4.47Å; V65-F96 HydrophobicContact CG2-CG 3.68Å; V65-F96 HydrophobicContact CG2-CZ 4.31Å; D67-F96 HydrophobicContact CB-CE1 3.84Å; D67-F96 HydrophobicContact CB-CZ 3.77Å; N71-F96 HydrophobicContact CB-CE2 4.45Å; N71-F96 HydrophobicContact CB-CZ 4.47Å; F73-F96 HydrophobicContact CB-CD2 3.27Å; F73-F96 HydrophobicContact CB-CE2 3.46Å; F73-F96 VanDerWaalsContact CB-CE2 3.46Å; F73-F96 HydrophobicContact CB-CG 4.03Å; F73-F96 HydrophobicContact CB-CZ 4.35Å; F73-F96 HydrophobicContact CD1-CB 3.78Å; F73-F96 AromaticContact CD1-CD2 3.98Å; F73-F96 HydrophobicContact CD1-CD2 3.98Å; F73-F96 HydrophobicContact CD1-CG 4.14Å; F73-F96 HydrophobicContact CE1-CB 4.34Å; F73-F96 HydrophobicContact CG-CB 4.47Å; F73-F96 AromaticContact CG-CD2 3.79Å; F73-F96 HydrophobicContact CG-CD2 3.79Å; F73-F96 HydrophobicContact CG-CE2 4.43Å; F73-F96 HydrophobicContact CG-CG 4.4Å; T92-F96 VanDerWaalsContact O-CB 3.27Å; T92-F96 WeakPolarHBondContact O-CB 3.45Å; T92-F96 PolarHBondContact O-N 2.56Å; Q93-F96 PolarHBondContact O-N 2.87Å; I94-F96 VanDerWaalsContact C-N 3.34Å; I94-F96 PolarHBondContact O-N 3.11Å; F96-Y98 PolarHBondContact O-N 3.41Å; F96-L99 PolarHBondContact O-N 2.87Å; F96-S100 WeakPolarHBondContact O-CB 3.36Å; F96-S100 PolarHBondContact O-N 3.46Å; F96-S100 PolarHBondContact O-OG 3.32Å; F96-Y123 HydrophobicContact CD2-CE2 4.47Å; F96-Y123 HydrophobicContact CE2-CD2 4.43Å; F96-Y123 AromaticContact CE2-CE2 3.97Å; F96-Y123 HydrophobicContact CE2-CE2 3.97Å
97N95.9Very high94.4Very high80 Ų8057 Ų5743%0.42830%0.297SS..Hα-helixtrans-61.4-44.2176.3-68.5-11.9000112.1Q93 I94 L95 S101Q93-N97 PolarHBondContact NE2-OD1 2.79Å; Q93-N97 PolarHBondContact O-N 2.84Å; Q93-N97 PolarHBondContact O-ND2 3.39Å; Q93-N97 PolarHBondContact O-OD1 2.84Å; I94-N97 PolarHBondContact O-N 2.93Å; L95-N97 VanDerWaalsContact C-N 3.34Å; L95-N97 PolarHBondContact O-N 3.33Å; N97-S101 PolarHBondContact O-N 2.89Å; N97-S101 PolarHBondContact O-OG 3.03Å
98Y96.6Very high95.1Very high110 Ų11054.1 Ų54.143%0.43127%0.273SS..Hα-helixtrans-62.6-48.2174-75.3-63.3000111.3I83 I94 L95 F96 S100 S101 C102 L111I83-Y98 HydrophobicContact CD1-CD2 4.28Å; I83-Y98 HydrophobicContact CD1-CE2 4.49Å; I94-Y98 HydrophobicContact CG2-CD2 3.91Å; I94-Y98 HydrophobicContact CG2-CE2 3.55Å; I94-Y98 WeakPolarHBondContact O-CD2 3.28Å; I94-Y98 PolarHBondContact O-N 2.87Å; L95-Y98 PolarHBondContact O-N 2.78Å; F96-Y98 PolarHBondContact O-N 3.41Å; Y98-S100 VanDerWaalsContact C-N 3.34Å; Y98-S100 PolarHBondContact O-N 2.92Å; Y98-S101 WeakPolarHBondContact O-CA 3.33Å; Y98-S101 WeakPolarHBondContact O-CB 3.25Å; Y98-S101 PolarHBondContact O-N 2.87Å; Y98-C102 PolarHBondContact O-N 3.39Å; Y98-C102 PolarHBondContact O-SG 2.88Å; Y98-C102 VanDerWaalsContact O-SG 3.4Å; Y98-L111 HydrophobicContact CG-CD1 4.24Å
99L96.1Very high95.6Very high0 Ų046.2 Ų46.20%024%0.236CC..Hα-helixtrans-62.4-41-177.7-171.860.6000112.4F73 L95 F96 S101 C102 I108 L111 F112 Y123F73-L99 HydrophobicContact CD2-CD2 3.91Å; F73-L99 HydrophobicContact CE2-CD2 3.92Å; L95-L99 VanDerWaalsContact O-CB 3.28Å; L95-L99 WeakPolarHBondContact O-CB 3.39Å; L95-L99 PolarHBondContact O-N 2.83Å; F96-L99 PolarHBondContact O-N 2.87Å; L99-S101 PolarHBondContact O-N 2.73Å; L99-C102 WeakPolarHBondContact O-CB 3.46Å; L99-C102 PolarHBondContact O-N 3.45Å; L99-I108 HydrophobicContact CD1-CB 4.43Å; L99-I108 HydrophobicContact CD1-CD1 4.44Å; L99-I108 HydrophobicContact CD1-CG1 3.99Å; L99-I108 HydrophobicContact CD1-CG2 3.95Å; L99-L111 HydrophobicContact CB-CD2 4.12Å; L99-L111 HydrophobicContact CD1-CD2 4.23Å; L99-F112 HydrophobicContact CD1-CE2 4.03Å; L99-Y123 HydrophobicContact CD1-CD1 4.09Å; L99-Y123 HydrophobicContact CD1-CE1 3.93Å; L99-Y123 HydrophobicContact CD2-CD1 3.56Å; L99-Y123 HydrophobicContact CD2-CD2 3.51Å; L99-Y123 HydrophobicContact CD2-CE1 3.81Å; L99-Y123 HydrophobicContact CD2-CE2 3.78Å; L99-Y123 HydrophobicContact CD2-CG 3.39Å; L99-Y123 HydrophobicContact CG-CD1 3.87Å; L99-Y123 HydrophobicContact CG-CD2 4.23Å; L99-Y123 HydrophobicContact CG-CE1 3.61Å; L99-Y123 HydrophobicContact CG-CE2 4.01Å; L99-Y123 HydrophobicContact CG-CG 4.17Å
100S94.5Very high95.9Very high16 Ų1645.6 Ų45.611%0.11224%0.24CC..THydrogen-bonded Turntrans-66.4-13.6173.3-83.10000113.5D67 R69 F96 Y98D67-S100 PolarHBondContact OD2-OG 2.84Å; R69-S100 PolarHBondContact NH1-O 2.84Å; R69-S100 PolarHBondContact NH2-O 2.87Å; F96-S100 WeakPolarHBondContact O-CB 3.36Å; F96-S100 PolarHBondContact O-N 3.46Å; F96-S100 PolarHBondContact O-OG 3.32Å; Y98-S100 VanDerWaalsContact C-N 3.34Å; Y98-S100 PolarHBondContact O-N 2.92Å
101S94.5Very high96.1Very high85 Ų8545.3 Ų45.359%0.59424%0.239SC*.THydrogen-bonded Turntrans-96.2-14.2175.5-56.90000112.8N97 Y98 L99 K103N97-S101 PolarHBondContact O-N 2.89Å; N97-S101 PolarHBondContact O-OG 3.03Å; Y98-S101 WeakPolarHBondContact O-CA 3.33Å; Y98-S101 WeakPolarHBondContact O-CB 3.25Å; Y98-S101 PolarHBondContact O-N 2.87Å; L99-S101 PolarHBondContact O-N 2.73Å; S101-K103 PolarHBondContact O-N 3.05Å
102C96.3Very high96.3Very high24 Ų2445.1 Ų45.116%0.16224%0.237CC..  trans-66.5130.4178.5-64.70000111.5Y98 L99 E107 I108Y98-C102 PolarHBondContact O-N 3.39Å; Y98-C102 PolarHBondContact O-SG 2.88Å; Y98-C102 VanDerWaalsContact O-SG 3.4Å; L99-C102 WeakPolarHBondContact O-CB 3.46Å; L99-C102 PolarHBondContact O-N 3.45Å; C102-E107 VanDerWaalsContact CA-OE2 3.32Å; C102-E107 WeakPolarHBondContact CA-OE2 3.47Å; C102-E107 HydrophobicContact CB-CB 3.91Å; C102-I108 HydrophobicContact CB-CG1 3.71Å
103K92.9Very high96.3Very high185 Ų18545.8 Ų45.880%0.80424%0.242SC*.  trans-95.9-20.4-176.3-63176.6-176.9172.40113.7S101 E107S101-K103 PolarHBondContact O-N 3.05Å; K103-E107 PolarHBondContact N-OE2 3.27Å
104N94.3Very high96.4Very high72 Ų7247 Ų4739%0.38525%0.248SC..SBendtrans-150.5171.3-174.458.967.6000111.1S106 E107 I108N104-S106 VanDerWaalsContact C-N 3.3Å; N104-S106 PolarHBondContact O-N 3.39Å; N104-S106 WeakPolarHBondContact OD1-CB 3.14Å; N104-S106 PolarHBondContact OD1-N 3.39Å; N104-S106 VanDerWaalsContact OD1-N 3.09Å; N104-E107 PolarHBondContact ND2-OE1 2.73Å; N104-E107 PolarHBondContact O-N 3.36Å; N104-E107 PolarHBondContact OD1-N 3.32Å; N104-I108 PolarHBondContact O-N 3.24Å
105E95.7Very high96.5Very high50 Ų5045.9 Ų45.923%0.23424%0.242CC..Hα-helixtrans-60.9-37.7-178.5-56.8176.8-170.900112.4E107 I108 L109 W132 R180 Y197 L235E105-E107 VanDerWaalsContact C-N 3.34Å; E105-E107 PolarHBondContact O-N 3.37Å; E105-I108 PolarHBondContact O-N 2.89Å; E105-L109 WeakPolarHBondContact O-CG 3.39Å; E105-L109 PolarHBondContact O-N 3.38Å; E105-W132 HydrophobicContact CB-CH2 4.06Å; E105-W132 HydrophobicContact CG-CH2 3.83Å; E105-W132 HydrophobicContact CG-CZ2 4Å; E105-R180 IonicContact OE1-CZ 2.69Å; E105-R180 IonicContact OE1-NH1 3.95Å; E105-R180 PolarHBondContact OE1-NH1 2.88Å; E105-R180 IonicContact OE1-NH2 3.19Å; E105-Y197 HydrophobicContact CB-CE1 4.5Å; E105-Y197 PolarHBondContact OE1-OH 2.94Å; E105-Y197 VanDerWaalsContact OE2-CE1 3.25Å; E105-Y197 WeakPolarHBondContact OE2-CE1 3.32Å; E105-Y197 PolarHBondContact OE2-OH 2.68Å; E105-L235 HydrophobicContact CB-CD1 3.8Å
106S96.4Very high96.5Very high63 Ų6347.7 Ų47.744%0.44125%0.251SS..Hα-helixtrans-63.9-38.9-178.9-167.80000112.1N104 L109 S110N104-S106 VanDerWaalsContact C-N 3.3Å; N104-S106 PolarHBondContact O-N 3.39Å; N104-S106 WeakPolarHBondContact OD1-CB 3.14Å; N104-S106 PolarHBondContact OD1-N 3.39Å; N104-S106 VanDerWaalsContact OD1-N 3.09Å; S106-L109 PolarHBondContact O-N 2.81Å; S106-S110 WeakPolarHBondContact O-CB 3.29Å; S106-S110 PolarHBondContact O-N 3.24Å
107E97.4Very high96.4Very high73 Ų7347.4 Ų47.434%0.34125%0.25SC..Hα-helixtrans-67.2-39.2176.9-72.1171.4-150.900111.7C102 K103 N104 E105 L109 S110 L111C102-E107 VanDerWaalsContact CA-OE2 3.32Å; C102-E107 WeakPolarHBondContact CA-OE2 3.47Å; C102-E107 HydrophobicContact CB-CB 3.91Å; K103-E107 PolarHBondContact N-OE2 3.27Å; N104-E107 PolarHBondContact ND2-OE1 2.73Å; N104-E107 PolarHBondContact O-N 3.36Å; N104-E107 PolarHBondContact OD1-N 3.32Å; E105-E107 VanDerWaalsContact C-N 3.34Å; E105-E107 PolarHBondContact O-N 3.37Å; E107-L109 VanDerWaalsContact C-N 3.35Å; E107-S110 PolarHBondContact O-N 3.2Å; E107-L111 WeakPolarHBondContact O-CB 3.48Å; E107-L111 PolarHBondContact O-N 3.39Å
108I97.7Very high96.5Very high2 Ų243.7 Ų43.71%0.0123%0.23CC..Hα-helixtrans-61.2-45.9173.5-62.5176.9000110.2L99 C102 N104 E105 L111 F112 W132L99-I108 HydrophobicContact CD1-CB 4.43Å; L99-I108 HydrophobicContact CD1-CD1 4.44Å; L99-I108 HydrophobicContact CD1-CG1 3.99Å; L99-I108 HydrophobicContact CD1-CG2 3.95Å; C102-I108 HydrophobicContact CB-CG1 3.71Å; N104-I108 PolarHBondContact O-N 3.24Å; E105-I108 PolarHBondContact O-N 2.89Å; I108-L111 PolarHBondContact O-N 2.85Å; I108-F112 HydrophobicContact CG2-CD2 3.88Å; I108-F112 HydrophobicContact CG2-CE2 4.02Å; I108-F112 WeakPolarHBondContact O-CD2 3.42Å; I108-F112 PolarHBondContact O-N 3.35Å; I108-W132 HydrophobicContact CD1-CZ2 4.1Å
109L97.9Very high96.6Very high3 Ų338.6 Ų38.62%0.01621%0.21CC..Hα-helixtrans-67.6-39.9-178.8-64.4166.9000112.2E105 S106 E107 F112 S113 L178 Y197 L235 L237E105-L109 WeakPolarHBondContact O-CG 3.39Å; E105-L109 PolarHBondContact O-N 3.38Å; S106-L109 PolarHBondContact O-N 2.81Å; E107-L109 VanDerWaalsContact C-N 3.35Å; L109-F112 PolarHBondContact O-N 3.13Å; L109-S113 WeakPolarHBondContact O-CB 3.39Å; L109-S113 PolarHBondContact O-N 3.23Å; L109-S113 PolarHBondContact O-OG 3.39Å; L109-L178 HydrophobicContact CD2-CD1 3.99Å; L109-L178 HydrophobicContact CD2-CG 4.47Å; L109-Y197 HydrophobicContact CD1-CD1 3.55Å; L109-Y197 HydrophobicContact CD1-CE1 4.15Å; L109-Y197 HydrophobicContact CD1-CG 4.22Å; L109-Y197 HydrophobicContact CD2-CD1 4.08Å; L109-Y197 HydrophobicContact CD2-CG 3.89Å; L109-Y197 HydrophobicContact CG-CD1 4.37Å; L109-L235 HydrophobicContact CD1-CB 3.45Å; L109-L235 VanDerWaalsContact CD1-CB 3.45Å; L109-L235 HydrophobicContact CD1-CD1 4.04Å; L109-L235 HydrophobicContact CD1-CG 4.32Å; L109-L237 HydrophobicContact CB-CG 4.49Å; L109-L237 HydrophobicContact CD2-CD1 3.66Å; L109-L237 HydrophobicContact CD2-CD2 4.44Å; L109-L237 HydrophobicContact CD2-CG 3.8Å
110S97.1Very high96.7Very high60 Ų6038.6 Ų38.642%0.4221%0.21SC..Hα-helixtrans-59.7-47.8173.7-165.20000110.6S106 E107 F112 S113 E114S106-S110 WeakPolarHBondContact O-CB 3.29Å; S106-S110 PolarHBondContact O-N 3.24Å; E107-S110 PolarHBondContact O-N 3.2Å; S110-F112 PolarHBondContact O-N 3.23Å; S110-S113 WeakPolarHBondContact O-CB 3.37Å; S110-S113 PolarHBondContact O-N 3.1Å; S110-S113 VanDerWaalsContact O-N 3.13Å; S110-E114 PolarHBondContact O-N 3.13Å; S110-E114 VanDerWaalsContact O-N 3.1Å
111L98.1Very high96.9Very high15 Ų1537.8 Ų37.88%0.07920%0.204CC..Hα-helixtrans-56.2-50.8177.9176.462.4000111.7I83 L95 Y98 L99 E107 I108 S113 E114 V115I83-L111 HydrophobicContact CG2-CD1 4.08Å; L95-L111 HydrophobicContact CD1-CD1 4.03Å; L95-L111 HydrophobicContact CD1-CD2 3.85Å; L95-L111 HydrophobicContact CD1-CG 3.92Å; Y98-L111 HydrophobicContact CG-CD1 4.24Å; L99-L111 HydrophobicContact CB-CD2 4.12Å; L99-L111 HydrophobicContact CD1-CD2 4.23Å; E107-L111 WeakPolarHBondContact O-CB 3.48Å; E107-L111 PolarHBondContact O-N 3.39Å; I108-L111 PolarHBondContact O-N 2.85Å; L111-S113 VanDerWaalsContact C-N 3.29Å; L111-S113 PolarHBondContact O-N 3.41Å; L111-E114 PolarHBondContact O-N 2.92Å; L111-V115 WeakPolarHBondContact O-CG2 3.43Å; L111-V115 PolarHBondContact O-N 3.45Å
112F98.1Very high97.1Very high0 Ų033.8 Ų33.80%018%0.176CC..Hα-helixtrans-72-20.3179.4-80.7-74.7000114.1W75 L95 L99 I108 L109 S110 E114 W119 F121 L178 L237W75-F112 HydrophobicContact CZ3-CE1 4.17Å; L95-F112 HydrophobicContact CD2-CE1 4.27Å; L99-F112 HydrophobicContact CD1-CE2 4.03Å; I108-F112 HydrophobicContact CG2-CD2 3.88Å; I108-F112 HydrophobicContact CG2-CE2 4.02Å; I108-F112 WeakPolarHBondContact O-CD2 3.42Å; I108-F112 PolarHBondContact O-N 3.35Å; L109-F112 PolarHBondContact O-N 3.13Å; S110-F112 PolarHBondContact O-N 3.23Å; F112-E114 VanDerWaalsContact C-N 3.34Å; F112-W119 HydrophobicContact CB-CH2 4.41Å; F112-W119 HydrophobicContact CD1-CE3 4.41Å; F112-W119 AromaticContact CD1-CH2 3.77Å; F112-W119 HydrophobicContact CD1-CH2 3.77Å; F112-W119 AromaticContact CD1-CZ2 3.96Å; F112-W119 HydrophobicContact CD1-CZ2 3.96Å; F112-W119 AromaticContact CD1-CZ3 3.99Å; F112-W119 HydrophobicContact CD1-CZ3 3.99Å; F112-W119 HydrophobicContact CE1-CE3 4.47Å; F112-W119 HydrophobicContact CE1-CZ3 4.31Å; F112-W119 HydrophobicContact CG-CH2 4.43Å; F112-F121 HydrophobicContact CD1-CD1 4.18Å; F112-F121 AromaticContact CD1-CE1 3.83Å; F112-F121 HydrophobicContact CD1-CE1 3.83Å; F112-F121 HydrophobicContact CD2-CE1 4.3Å; F112-F121 HydrophobicContact CD2-CZ 4.22Å; F112-F121 AromaticContact CE1-CD1 3.36Å; F112-F121 HydrophobicContact CE1-CD1 3.36Å; F112-F121 HydrophobicContact CE1-CD2 4.49Å; F112-F121 AromaticContact CE1-CE1 3.32Å; F112-F121 HydrophobicContact CE1-CE1 3.32Å; F112-F121 HydrophobicContact CE1-CE2 4.48Å; F112-F121 AromaticContact CE1-CG 3.98Å; F112-F121 HydrophobicContact CE1-CG 3.98Å; F112-F121 AromaticContact CE1-CZ 3.94Å; F112-F121 HydrophobicContact CE1-CZ 3.94Å; F112-F121 HydrophobicContact CE2-CD1 4.49Å; F112-F121 AromaticContact CE2-CE1 3.86Å; F112-F121 HydrophobicContact CE2-CE1 3.86Å; F112-F121 HydrophobicContact CE2-CE2 4.01Å; F112-F121 AromaticContact CE2-CZ 3.6Å; F112-F121 HydrophobicContact CE2-CZ 3.6Å; F112-F121 HydrophobicContact CG-CE1 4.3Å; F112-F121 AromaticContact CZ-CD1 3.56Å; F112-F121 HydrophobicContact CZ-CD1 3.56Å; F112-F121 AromaticContact CZ-CD2 3.88Å; F112-F121 HydrophobicContact CZ-CD2 3.88Å; F112-F121 AromaticContact CZ-CE1 3.34Å; F112-F121 HydrophobicContact CZ-CE1 3.34Å; F112-F121 AromaticContact CZ-CE2 3.71Å; F112-F121 HydrophobicContact CZ-CE2 3.71Å; F112-F121 AromaticContact CZ-CG 3.82Å; F112-F121 HydrophobicContact CZ-CG 3.82Å; F112-F121 AromaticContact CZ-CZ 3.44Å; F112-F121 HydrophobicContact CZ-CZ 3.44Å; F112-F121 VanDerWaalsContact CZ-CZ 3.44Å; F112-L178 HydrophobicContact CB-CD1 4.04Å; F112-L178 HydrophobicContact CD2-CD1 3.76Å; F112-L178 HydrophobicContact CE2-CD1 4.47Å; F112-L178 HydrophobicContact CG-CD1 3.98Å; F112-L237 HydrophobicContact CB-CD2 3.67Å
113S97.4Very high97.2Very high18 Ų1832.9 Ų32.913%0.12617%0.169CC..Hα-helixtrans-71.7-31.8171.7-58.40000111.7L109 S110 L111 L237 E238L109-S113 WeakPolarHBondContact O-CB 3.39Å; L109-S113 PolarHBondContact O-N 3.23Å; L109-S113 PolarHBondContact O-OG 3.39Å; S110-S113 WeakPolarHBondContact O-CB 3.37Å; S110-S113 PolarHBondContact O-N 3.1Å; S110-S113 VanDerWaalsContact O-N 3.13Å; L111-S113 VanDerWaalsContact C-N 3.29Å; L111-S113 PolarHBondContact O-N 3.41Å; S113-L237 VanDerWaalsContact OG-CA 3.28Å; S113-L237 WeakPolarHBondContact OG-CA 3.15Å; S113-L237 WeakPolarHBondContact OG-CB 3.46Å; S113-E238 PolarHBondContact OG-N 2.84Å
114E96.9Very high97.5Very high99 Ų9924.7 Ų24.746%0.46313%0.133SC..Hα-helixtrans-77-32.7178.8-71.1175.1-155.400112.7G82 I83 S110 L111 F112 Q116G82-E114 WeakPolarHBondContact CA-O 3.31Å; I83-E114 HydrophobicContact CG2-CB 3.91Å; S110-E114 PolarHBondContact O-N 3.13Å; S110-E114 VanDerWaalsContact O-N 3.1Å; L111-E114 PolarHBondContact O-N 2.92Å; F112-E114 VanDerWaalsContact C-N 3.34Å; E114-Q116 PolarHBondContact O-N 3.42Å; E114-Q116 VanDerWaalsContact O-N 3.13Å
115V97.8Very high97.6Very high4 Ų422.5 Ų22.52%0.02412%0.121CC..  trans-62.8115.8-174.5178.70000112W75 I79 I83 L95 L111W75-V115 HydrophobicContact CH2-CG1 4.26Å; I79-V115 HydrophobicContact CD1-CG1 4.13Å; I79-V115 HydrophobicContact CD1-CG2 4.46Å; I79-V115 HydrophobicContact CG1-CG1 3.91Å; I79-V115 HydrophobicContact CG2-CG1 4.41Å; I83-V115 HydrophobicContact CD1-CG2 4.13Å; I83-V115 HydrophobicContact CG1-CG2 4.3Å; I83-V115 HydrophobicContact CG2-CG2 4.11Å; L95-V115 HydrophobicContact CD1-CG2 4.17Å; L111-V115 WeakPolarHBondContact O-CG2 3.43Å; L111-V115 PolarHBondContact O-N 3.45Å
116Q97.2Very high97.6Very high37 Ų3721.2 Ų21.217%0.17312%0.119CC..BIsolated β-bridgetrans-105.1125.2172.9-61.1-178.4-600111F80 S81 E114 E555F80-Q116 PolarHBondContact N-O 3.07Å; S81-Q116 PolarHBondContact N-O 3.37Å; S81-Q116 WeakPolarHBondContact O-CB 3.39Å; S81-Q116 PolarHBondContact O-N 2.84Å; S81-Q116 PolarHBondContact OG-OE1 2.89Å; E114-Q116 PolarHBondContact O-N 3.42Å; E114-Q116 VanDerWaalsContact O-N 3.13Å; Q116-E555 HydrophobicContact CB-CG 4.23Å; Q116-E555 HydrophobicContact CG-CB 4.39Å; Q116-E555 HydrophobicContact CG-CG 4.13Å
117G96.7Very high97.5Very high0 Ų023.5 Ų23.50%014%0.135CC..SBendtrans136.8167.3-174.600000112.8E78 R140 E555E78-G117 WeakPolarHBondContact O-CA 3.42Å; G117-R140 VanDerWaalsContact C-NH2 3.31Å; G117-R140 PolarHBondContact O-NH2 2.94Å; G117-E555 PolarHBondContact N-OE1 2.67Å
118P97.2Very high97.4Very high2 Ų221.7 Ų21.71%0.01313%0.13CC..  trans-75.8128.7-177.931.6-34.9000110.9G77 E78 F80 R140 R141G77-P118 CarbonylContact C-O 3.59Å; G77-P118 WeakPolarHBondContact CA-O 3.21Å; E78-P118 HydrophobicContact CB-CG 4.39Å; E78-P118 PolarHBondContact N-O 2.99Å; E78-P118 WeakPolarHBondContact O-CD 3.45Å; F80-P118 VanDerWaalsContact CE2-CD 3.46Å; F80-P118 HydrophobicContact CE2-CG 4.06Å; P118-R140 HydrophobicContact CB-CB 3.51Å; P118-R140 HydrophobicContact CB-CG 4.36Å; P118-R141 HydrophobicContact CB-CG 4.07Å
119W97.9Very high97.3Very high2 Ų223.2 Ų23.21%0.00814%0.137CC..EExtended strand (participates in β ladder)trans-155.7151179.654.1-100.8000115.3W75 N76 F112 F121 R135 D136 L178 W199W75-W119 HydrophobicContact CE3-CB 4.32Å; W75-W119 HydrophobicContact CH2-CB 3.05Å; W75-W119 AromaticContact CH2-CD1 3.79Å; W75-W119 HydrophobicContact CH2-CD2 4.1Å; W75-W119 AromaticContact CH2-CG 3.37Å; W75-W119 HydrophobicContact CH2-CG 3.37Å; W75-W119 HydrophobicContact CZ2-CB 3.54Å; W75-W119 HydrophobicContact CZ2-CG 4.2Å; W75-W119 HydrophobicContact CZ3-CB 3.49Å; W75-W119 VanDerWaalsContact CZ3-CB 3.49Å; W75-W119 HydrophobicContact CZ3-CD2 4.22Å; W75-W119 HydrophobicContact CZ3-CE3 4.38Å; W75-W119 AromaticContact CZ3-CG 3.87Å; W75-W119 HydrophobicContact CZ3-CG 3.87Å; N76-W119 CarbonylContact O-C 3.52Å; N76-W119 WeakPolarHBondContact O-CA 3.37Å; F112-W119 HydrophobicContact CB-CH2 4.41Å; F112-W119 HydrophobicContact CD1-CE3 4.41Å; F112-W119 AromaticContact CD1-CH2 3.77Å; F112-W119 HydrophobicContact CD1-CH2 3.77Å; F112-W119 AromaticContact CD1-CZ2 3.96Å; F112-W119 HydrophobicContact CD1-CZ2 3.96Å; F112-W119 AromaticContact CD1-CZ3 3.99Å; F112-W119 HydrophobicContact CD1-CZ3 3.99Å; F112-W119 HydrophobicContact CE1-CE3 4.47Å; F112-W119 HydrophobicContact CE1-CZ3 4.31Å; F112-W119 HydrophobicContact CG-CH2 4.43Å; W119-F121 AromaticContact CE3-CD1 3.86Å; W119-F121 HydrophobicContact CE3-CD1 3.86Å; W119-F121 HydrophobicContact CE3-CE1 4.37Å; W119-F121 HydrophobicContact CH2-CE1 4.49Å; W119-F121 AromaticContact CZ3-CD1 3.69Å; W119-F121 HydrophobicContact CZ3-CD1 3.69Å; W119-F121 AromaticContact CZ3-CE1 3.73Å; W119-F121 HydrophobicContact CZ3-CE1 3.73Å; W119-R135 VanDerWaalsContact CE3-C 3.49Å; W119-R135 VanDerWaalsContact CH2-O 3.28Å; W119-R135 WeakPolarHBondContact CH2-O 3.34Å; W119-R135 VanDerWaalsContact CZ3-O 3.31Å; W119-R135 WeakPolarHBondContact CZ3-O 3.33Å; W119-R135 CarbonylContact O-C 3.47Å; W119-R135 WeakPolarHBondContact O-CA 3.42Å; W119-D136 HydrophobicContact CD2-CB 3.68Å; W119-D136 VanDerWaalsContact CE2-CA 3.48Å; W119-D136 HydrophobicContact CE3-CB 4.36Å; W119-D136 VanDerWaalsContact CE3-N 3.33Å; W119-D136 HydrophobicContact CG-CB 3.8Å; W119-D136 HydrophobicContact CZ2-CB 4.11Å; W119-D136 PolarHBondContact N-OD2 3.48Å; W119-D136 VanDerWaalsContact N-OD2 3.12Å; W119-D136 PolarHBondContact O-N 2.82Å; W119-L178 HydrophobicContact CH2-CD2 3.94Å; W119-L178 HydrophobicContact CZ3-CD2 4.05Å; W119-W199 HydrophobicContact CH2-CH2 4.33Å; W119-W199 AromaticContact CH2-CZ2 3.95Å; W119-W199 HydrophobicContact CH2-CZ2 3.95Å; W119-W199 AromaticContact CZ2-CH2 3.99Å; W119-W199 HydrophobicContact CZ2-CH2 3.99Å; W119-W199 AromaticContact CZ2-CZ2 3.95Å; W119-W199 HydrophobicContact CZ2-CZ2 3.95Å
120S98.6Very high97.3Very high0 Ų025.8 Ų25.80%015%0.147CC..EExtended strand (participates in β ladder)trans-138.6149.2157.764.10000109.2N76 G134 S142N76-S120 CarbonylContact C-O 3.57Å; N76-S120 PolarHBondContact N-O 3.44Å; N76-S120 PolarHBondContact ND2-OG 3.48Å; N76-S120 PolarHBondContact O-N 2.61Å; S120-G134 VanDerWaalsContact CA-O 3.31Å; S120-G134 WeakPolarHBondContact CA-O 3.32Å; S120-S142 PolarHBondContact OG-O 2.73Å
121F98.8Very high97.3Very high0 Ų023 Ų230%013%0.127CC..EExtended strand (participates in β ladder)trans-146.5162.5-175.679.9-88.6000113.4F73 L74 W75 F112 W119 W132 F133 G134 L178F73-F121 HydrophobicContact CE2-CB 3.83Å; F73-F121 AromaticContact CE2-CD2 3.91Å; F73-F121 HydrophobicContact CE2-CD2 3.91Å; F73-F121 HydrophobicContact CE2-CG 4.15Å; F73-F121 HydrophobicContact CZ-CB 4.31Å; L74-F121 CarbonylContact O-C 3.58Å; L74-F121 VanDerWaalsContact O-CA 3.24Å; L74-F121 WeakPolarHBondContact O-CA 3.25Å; L74-F121 WeakPolarHBondContact O-CB 3.42Å; W75-F121 HydrophobicContact CE3-CB 3.84Å; W75-F121 HydrophobicContact CZ3-CB 4.2Å; F112-F121 HydrophobicContact CD1-CD1 4.18Å; F112-F121 AromaticContact CD1-CE1 3.83Å; F112-F121 HydrophobicContact CD1-CE1 3.83Å; F112-F121 HydrophobicContact CD2-CE1 4.3Å; F112-F121 HydrophobicContact CD2-CZ 4.22Å; F112-F121 AromaticContact CE1-CD1 3.36Å; F112-F121 HydrophobicContact CE1-CD1 3.36Å; F112-F121 HydrophobicContact CE1-CD2 4.49Å; F112-F121 AromaticContact CE1-CE1 3.32Å; F112-F121 HydrophobicContact CE1-CE1 3.32Å; F112-F121 HydrophobicContact CE1-CE2 4.48Å; F112-F121 AromaticContact CE1-CG 3.98Å; F112-F121 HydrophobicContact CE1-CG 3.98Å; F112-F121 AromaticContact CE1-CZ 3.94Å; F112-F121 HydrophobicContact CE1-CZ 3.94Å; F112-F121 HydrophobicContact CE2-CD1 4.49Å; F112-F121 AromaticContact CE2-CE1 3.86Å; F112-F121 HydrophobicContact CE2-CE1 3.86Å; F112-F121 HydrophobicContact CE2-CE2 4.01Å; F112-F121 AromaticContact CE2-CZ 3.6Å; F112-F121 HydrophobicContact CE2-CZ 3.6Å; F112-F121 HydrophobicContact CG-CE1 4.3Å; F112-F121 AromaticContact CZ-CD1 3.56Å; F112-F121 HydrophobicContact CZ-CD1 3.56Å; F112-F121 AromaticContact CZ-CD2 3.88Å; F112-F121 HydrophobicContact CZ-CD2 3.88Å; F112-F121 AromaticContact CZ-CE1 3.34Å; F112-F121 HydrophobicContact CZ-CE1 3.34Å; F112-F121 AromaticContact CZ-CE2 3.71Å; F112-F121 HydrophobicContact CZ-CE2 3.71Å; F112-F121 AromaticContact CZ-CG 3.82Å; F112-F121 HydrophobicContact CZ-CG 3.82Å; F112-F121 AromaticContact CZ-CZ 3.44Å; F112-F121 HydrophobicContact CZ-CZ 3.44Å; F112-F121 VanDerWaalsContact CZ-CZ 3.44Å; W119-F121 AromaticContact CE3-CD1 3.86Å; W119-F121 HydrophobicContact CE3-CD1 3.86Å; W119-F121 HydrophobicContact CE3-CE1 4.37Å; W119-F121 HydrophobicContact CH2-CE1 4.49Å; W119-F121 AromaticContact CZ3-CD1 3.69Å; W119-F121 HydrophobicContact CZ3-CD1 3.69Å; W119-F121 AromaticContact CZ3-CE1 3.73Å; W119-F121 HydrophobicContact CZ3-CE1 3.73Å; F121-W132 HydrophobicContact CE2-CB 4.01Å; F121-W132 HydrophobicContact CZ-CB 4.49Å; F121-F133 WeakPolarHBondContact O-CA 3.37Å; F121-F133 WeakPolarHBondContact O-CB 3.25Å; F121-G134 PolarHBondContact N-O 3.15Å; F121-G134 VanDerWaalsContact N-O 3.15Å; F121-G134 PolarHBondContact O-N 3.01Å; F121-L178 HydrophobicContact CE1-CD1 4.33Å; F121-L178 HydrophobicContact CE1-CD2 3.5Å; F121-L178 HydrophobicContact CZ-CD1 4.07Å; F121-L178 HydrophobicContact CZ-CD2 3.89Å
122I98.8Very high97.4Very high1 Ų122.3 Ų22.31%0.00512%0.124CC..EExtended strand (participates in β ladder)trans-134.6127.1167.9-53.3166.9000107.6I4 C6 F49 L74 L131 W132 F133 L143 L156I4-I122 HydrophobicContact CD1-CD1 4.29Å; I4-I122 HydrophobicContact CD1-CG1 4.22Å; I4-I122 HydrophobicContact CG1-CD1 4.46Å; C6-I122 HydrophobicContact CB-CD1 3.79Å; C6-I122 HydrophobicContact CB-CG2 3.87Å; F49-I122 HydrophobicContact CE1-CG2 4.47Å; L74-I122 HydrophobicContact CB-CB 4.18Å; L74-I122 HydrophobicContact CD1-CB 4.38Å; L74-I122 HydrophobicContact CD1-CD1 4.27Å; L74-I122 PolarHBondContact N-O 2.61Å; L74-I122 PolarHBondContact O-N 3.09Å; I122-L131 HydrophobicContact CG2-CD1 3.65Å; I122-L131 HydrophobicContact CG2-CG 4.41Å; I122-W132 CarbonylContact C-O 3.56Å; I122-W132 WeakPolarHBondContact CA-O 3.38Å; I122-F133 HydrophobicContact CG1-CB 4.48Å; I122-L143 HydrophobicContact CD1-CD1 4.41Å; I122-L143 HydrophobicContact CG1-CD1 4.44Å; I122-L156 HydrophobicContact CD1-CB 3.69Å; I122-L156 HydrophobicContact CD1-CD1 4.36Å; I122-L156 HydrophobicContact CG1-CB 4.3Å; I122-L156 HydrophobicContact CG1-CD1 4.17Å; I122-L156 HydrophobicContact CG2-CD1 4.31Å
123Y98.7Very high97.4Very high4 Ų422.3 Ų22.32%0.01612%0.124CC..EExtended strand (participates in β ladder)trans-132.3119.3-179.3176.1-127.1000110.8N71 V72 F73 F96 L99 Q125 W132N71-Y123 HydrophobicContact CB-CE2 3.92Å; V72-Y123 CarbonylContact O-C 3.58Å; V72-Y123 WeakPolarHBondContact O-CA 3.45Å; V72-Y123 WeakPolarHBondContact O-CD2 3.43Å; F73-Y123 HydrophobicContact CB-CD2 4.16Å; F73-Y123 HydrophobicContact CD2-CD2 4.14Å; F73-Y123 HydrophobicContact CD2-CG 4.4Å; F96-Y123 HydrophobicContact CD2-CE2 4.47Å; F96-Y123 HydrophobicContact CE2-CD2 4.43Å; F96-Y123 AromaticContact CE2-CE2 3.97Å; F96-Y123 HydrophobicContact CE2-CE2 3.97Å; L99-Y123 HydrophobicContact CD1-CD1 4.09Å; L99-Y123 HydrophobicContact CD1-CE1 3.93Å; L99-Y123 HydrophobicContact CD2-CD1 3.56Å; L99-Y123 HydrophobicContact CD2-CD2 3.51Å; L99-Y123 HydrophobicContact CD2-CE1 3.81Å; L99-Y123 HydrophobicContact CD2-CE2 3.78Å; L99-Y123 HydrophobicContact CD2-CG 3.39Å; L99-Y123 HydrophobicContact CG-CD1 3.87Å; L99-Y123 HydrophobicContact CG-CD2 4.23Å; L99-Y123 HydrophobicContact CG-CE1 3.61Å; L99-Y123 HydrophobicContact CG-CE2 4.01Å; L99-Y123 HydrophobicContact CG-CG 4.17Å; Y123-Q125 HydrophobicContact CD1-CG 3.85Å; Y123-Q125 HydrophobicContact CE1-CG 3.19Å; Y123-W132 HydrophobicContact CD1-CB 4.34Å; Y123-W132 AromaticContact CD1-CD1 3.96Å; Y123-W132 HydrophobicContact CD1-CG 4.34Å; Y123-W132 PolarHBondContact N-O 3.01Å; Y123-W132 PolarHBondContact O-N 3.42Å
124Y98.4Very high97.4Very high13 Ų1321.4 Ų21.45%0.05112%0.118CC..EExtended strand (participates in β ladder)trans-102.4120.9175.9171.3-108.4000110.1K40 Y45 F49 N71 V72 A126 Y130 L183K40-Y124 HydrophobicContact CG-CE1 4.42Å; Y45-Y124 HydrophobicContact CE2-CE2 4.38Å; Y45-Y124 WeakPolarHBondContact OH-CE2 3.41Å; Y45-Y124 PolarHBondContact OH-OH 2.91Å; F49-Y124 HydrophobicContact CZ-CD1 4.24Å; F49-Y124 HydrophobicContact CZ-CD2 4.41Å; F49-Y124 AromaticContact CZ-CG 3.82Å; F49-Y124 HydrophobicContact CZ-CG 3.82Å; N71-Y124 CarbonylContact C-O 3.56Å; N71-Y124 WeakPolarHBondContact CA-O 3.32Å; N71-Y124 WeakPolarHBondContact CB-O 3.44Å; V72-Y124 HydrophobicContact CB-CD1 4.43Å; V72-Y124 HydrophobicContact CG2-CD1 4.19Å; V72-Y124 PolarHBondContact N-O 3.23Å; V72-Y124 PolarHBondContact O-N 3.35Å; Y124-A126 HydrophobicContact CE1-CB 3.86Å; Y124-Y130 WeakPolarHBondContact CA-O 3.47Å; Y124-L183 HydrophobicContact CD2-CD1 4.08Å; Y124-L183 HydrophobicContact CE2-CD1 3.92Å
125Q96.8Very high97.5Very high27 Ų2716.8 Ų16.813%0.12610%0.096CC..EExtended strand (participates in β ladder)trans-94.3110172.7-68.1-173.5-56.300109.7N71 Y123 S127 S128 H129 Y130N71-Q125 WeakPolarHBondContact OD1-CA 3.48Å; Y123-Q125 HydrophobicContact CD1-CG 3.85Å; Y123-Q125 HydrophobicContact CE1-CG 3.19Å; Q125-S127 PolarHBondContact O-N 3.12Å; Q125-S128 VanDerWaalsContact CB-OG 3.31Å; Q125-S128 WeakPolarHBondContact CB-OG 3Å; Q125-H129 WeakPolarHBondContact O-CA 3.43Å; Q125-H129 PolarHBondContact O-N 3.11Å; Q125-Y130 PolarHBondContact N-O 3.03Å; Q125-Y130 PolarHBondContact O-N 2.87Å
126A95.3Very high97.5Very high22 Ų2216.6 Ų16.618%0.18210%0.095CC..THydrogen-bonded Turntrans-67.3-40.3-172.700000112.9R69 N71 Y124 S128R69-A126 WeakPolarHBondContact O-CB 3.24Å; N71-A126 PolarHBondContact OD1-N 3.42Å; Y124-A126 HydrophobicContact CE1-CB 3.86Å; A126-S128 VanDerWaalsContact C-N 3.35Å; A126-S128 PolarHBondContact O-N 3.05Å
127S94.4Very high97.5Very high112 Ų11216.9 Ų16.978%0.78310%0.096SC*.THydrogen-bonded Turntrans-67.6-33.2-175.857.30000113.7Q125Q125-S127 PolarHBondContact O-N 3.12Å
128S95.3Very high97.5Very high34 Ų3417.6 Ų17.624%0.23810%0.099CC..THydrogen-bonded Turntrans-103.4-7.2-178.853.40000113.5Q125 A126 Y130Q125-S128 VanDerWaalsContact CB-OG 3.31Å; Q125-S128 WeakPolarHBondContact CB-OG 3Å; A126-S128 VanDerWaalsContact C-N 3.35Å; A126-S128 PolarHBondContact O-N 3.05Å; S128-Y130 VanDerWaalsContact O-CD1 3.3Å; S128-Y130 WeakPolarHBondContact O-CD1 3.47Å; S128-Y130 WeakPolarHBondContact O-CE1 3.38Å; S128-Y130 PolarHBondContact O-N 3.27Å; S128-Y130 VanDerWaalsContact OG-CD2 3.25Å; S128-Y130 WeakPolarHBondContact OG-CD2 3.33Å
129H96.4Very high97.5Very high34 Ų3417.5 Ų17.516%0.15710%0.098CC..THydrogen-bonded Turntrans58.227.4-172.4-53.1-95.5000113.3D42 Y45 Q125 L183 K184D42-H129 IonicContact OD2-CE1 3.55Å; D42-H129 PolarHBondContact OD2-CE1 2.96Å; Y45-H129 HydrophobicContact CE1-CB 4.25Å; Y45-H129 AromaticContact CE1-ND1 3.69Å; Y45-H129 AromaticContact CZ-ND1 3.63Å; Y45-H129 WeakPolarHBondContact OH-CB 3.33Å; Y45-H129 PolarHBondContact OH-ND1 3.15Å; Q125-H129 WeakPolarHBondContact O-CA 3.43Å; Q125-H129 PolarHBondContact O-N 3.11Å; H129-L183 WeakPolarHBondContact O-CB 3.24Å; H129-L183 WeakPolarHBondContact O-CG 3.35Å; H129-L183 PolarHBondContact O-N 2.95Å; H129-K184 HydrophobicContact CB-CB 4.12Å
130Y97.2Very high97.5Very high58 Ų5817.5 Ų17.523%0.22710%0.098CC..EExtended strand (participates in β ladder)trans-88.9133.6179.5-64.5-20000111.5Y124 Q125 S128 R180 I181 D182Y124-Y130 WeakPolarHBondContact CA-O 3.47Å; Q125-Y130 PolarHBondContact N-O 3.03Å; Q125-Y130 PolarHBondContact O-N 2.87Å; S128-Y130 VanDerWaalsContact O-CD1 3.3Å; S128-Y130 WeakPolarHBondContact O-CD1 3.47Å; S128-Y130 WeakPolarHBondContact O-CE1 3.38Å; S128-Y130 PolarHBondContact O-N 3.27Å; S128-Y130 VanDerWaalsContact OG-CD2 3.25Å; S128-Y130 WeakPolarHBondContact OG-CD2 3.33Å; Y130-R180 HydrophobicContact CG-CG 4.3Å; Y130-I181 WeakPolarHBondContact CA-O 3.33Å; Y130-D182 HydrophobicContact CD1-CB 4.05Å; Y130-D182 HydrophobicContact CE1-CB 3.89Å
131L98.4Very high97.4Very high0 Ų017.5 Ų17.50%010%0.098CC..EExtended strand (participates in β ladder)trans-109.2109.9170.8-171.968.3000109.2V8 F49 I122 F154 L156 R180 I181 L183V8-L131 HydrophobicContact CG2-CD2 4.01Å; F49-L131 HydrophobicContact CE1-CD1 4.21Å; I122-L131 HydrophobicContact CG2-CD1 3.65Å; I122-L131 HydrophobicContact CG2-CG 4.41Å; L131-F154 HydrophobicContact CD2-CD1 4.29Å; L131-F154 HydrophobicContact CD2-CE1 3.79Å; L131-L156 HydrophobicContact CD2-CD1 4.23Å; L131-R180 CarbonylContact O-C 3.59Å; L131-R180 WeakPolarHBondContact O-CA 3.41Å; L131-I181 PolarHBondContact N-O 2.92Å; L131-I181 PolarHBondContact O-N 3.2Å; L131-L183 HydrophobicContact CB-CD1 4.23Å; L131-L183 HydrophobicContact CB-CD2 4.05Å; L131-L183 HydrophobicContact CB-CG 4.13Å; L131-L183 HydrophobicContact CD2-CD2 4.25Å
132W98.7Very high97.3Very high1 Ų117.5 Ų17.50%0.00410%0.098CC..EExtended strand (participates in β ladder)trans-97.6141.8175.8-62.583.4000110.6E105 I108 F121 I122 Y123 F179 R180 Y197E105-W132 HydrophobicContact CB-CH2 4.06Å; E105-W132 HydrophobicContact CG-CH2 3.83Å; E105-W132 HydrophobicContact CG-CZ2 4Å; I108-W132 HydrophobicContact CD1-CZ2 4.1Å; F121-W132 HydrophobicContact CE2-CB 4.01Å; F121-W132 HydrophobicContact CZ-CB 4.49Å; I122-W132 CarbonylContact C-O 3.56Å; I122-W132 WeakPolarHBondContact CA-O 3.38Å; Y123-W132 HydrophobicContact CD1-CB 4.34Å; Y123-W132 AromaticContact CD1-CD1 3.96Å; Y123-W132 HydrophobicContact CD1-CG 4.34Å; Y123-W132 PolarHBondContact N-O 3.01Å; Y123-W132 PolarHBondContact O-N 3.42Å; W132-F179 WeakPolarHBondContact CA-O 3.16Å; W132-R180 HydrophobicContact CD2-CB 4.07Å; W132-R180 HydrophobicContact CD2-CG 3.97Å; W132-R180 HydrophobicContact CE3-CB 3.94Å; W132-R180 HydrophobicContact CE3-CG 4.33Å; W132-R180 HydrophobicContact CG-CG 4.41Å; W132-R180 HydrophobicContact CH2-CB 4.43Å; W132-R180 HydrophobicContact CH2-CG 4.49Å; W132-R180 HydrophobicContact CZ2-CG 4.15Å; W132-R180 HydrophobicContact CZ3-CB 4.13Å; W132-Y197 HydrophobicContact CE3-CE2 4.37Å; W132-Y197 HydrophobicContact CH2-CD2 4.4Å; W132-Y197 HydrophobicContact CH2-CE1 4.41Å; W132-Y197 AromaticContact CH2-CE2 3.7Å; W132-Y197 HydrophobicContact CH2-CE2 3.7Å; W132-Y197 AromaticContact CH2-CZ 3.68Å; W132-Y197 AromaticContact CZ3-CD2 3.7Å; W132-Y197 HydrophobicContact CZ3-CD2 3.7Å; W132-Y197 AromaticContact CZ3-CE2 3.4Å; W132-Y197 HydrophobicContact CZ3-CE2 3.4Å; W132-Y197 HydrophobicContact CZ3-CG 4.4Å; W132-Y197 AromaticContact CZ3-CZ 3.84Å
133F98.8Very high97.3Very high0 Ų017.4 Ų17.40%010%0.098CC..EExtended strand (participates in β ladder)trans-159.6161.1175.359.1-84.1000110.7F121 I122 L143 W145 F154 L156 V173 F179 I181 L194F121-F133 WeakPolarHBondContact O-CA 3.37Å; F121-F133 WeakPolarHBondContact O-CB 3.25Å; I122-F133 HydrophobicContact CG1-CB 4.48Å; F133-L143 HydrophobicContact CB-CD2 4.24Å; F133-L143 HydrophobicContact CD2-CD2 4.22Å; F133-W145 HydrophobicContact CE2-CE3 4.08Å; F133-W145 HydrophobicContact CE2-CZ3 4.36Å; F133-F154 HydrophobicContact CE1-CE1 4.5Å; F133-F154 HydrophobicContact CE1-CZ 4.05Å; F133-F154 AromaticContact CZ-CZ 4Å; F133-F154 HydrophobicContact CZ-CZ 4Å; F133-L156 HydrophobicContact CB-CD1 3.78Å; F133-L156 HydrophobicContact CD1-CD1 3.57Å; F133-L156 HydrophobicContact CD2-CD1 4.02Å; F133-L156 HydrophobicContact CD2-CD2 3.75Å; F133-L156 HydrophobicContact CE1-CD1 4.1Å; F133-L156 HydrophobicContact CE2-CD1 4.49Å; F133-L156 HydrophobicContact CE2-CD2 3.85Å; F133-L156 HydrophobicContact CG-CD1 3.51Å; F133-L156 HydrophobicContact CG-CD2 4.15Å; F133-L156 HydrophobicContact CG-CG 4.49Å; F133-L156 HydrophobicContact CZ-CD2 4.33Å; F133-V173 HydrophobicContact CD2-CG1 4.16Å; F133-V173 HydrophobicContact CE2-CG1 4.11Å; F133-V173 HydrophobicContact CE2-CG2 4.45Å; F133-F179 HydrophobicContact CD1-CB 4.29Å; F133-F179 HydrophobicContact CD2-CB 4Å; F133-F179 HydrophobicContact CD2-CD2 4.34Å; F133-F179 HydrophobicContact CE1-CB 3.82Å; F133-F179 HydrophobicContact CE2-CB 3.49Å; F133-F179 VanDerWaalsContact CE2-CB 3.49Å; F133-F179 AromaticContact CE2-CD2 3.97Å; F133-F179 HydrophobicContact CE2-CD2 3.97Å; F133-F179 AromaticContact CE2-CG 3.89Å; F133-F179 HydrophobicContact CE2-CG 3.89Å; F133-F179 HydrophobicContact CG-CB 4.38Å; F133-F179 HydrophobicContact CZ-CB 3.4Å; F133-F179 VanDerWaalsContact CZ-CB 3.4Å; F133-F179 HydrophobicContact CZ-CG 4.13Å; F133-F179 PolarHBondContact N-O 3.44Å; F133-F179 PolarHBondContact O-N 2.83Å; F133-I181 HydrophobicContact CE1-CD1 3.77Å; F133-I181 HydrophobicContact CE1-CG1 4Å; F133-I181 HydrophobicContact CZ-CD1 4.22Å; F133-L194 HydrophobicContact CZ-CD2 4.08Å
134G98.3Very high97.2Very high0 Ų017.2 Ų17.20%010%0.097CC..EExtended strand (participates in β ladder)trans171.7-173.5178.800000111.7S120 F121S120-G134 VanDerWaalsContact CA-O 3.31Å; S120-G134 WeakPolarHBondContact CA-O 3.32Å; F121-G134 PolarHBondContact N-O 3.15Å; F121-G134 VanDerWaalsContact N-O 3.15Å; F121-G134 PolarHBondContact O-N 3.01Å
135R98.1Very high97.1Very high1 Ų116.9 Ų16.90%0.00410%0.095CC..EExtended strand (participates in β ladder)trans-136.2158.2-178-57.7169.268.6-168.25109.2W119 G139 R141 L143 E172 V173W119-R135 VanDerWaalsContact CE3-C 3.49Å; W119-R135 VanDerWaalsContact CH2-O 3.28Å; W119-R135 WeakPolarHBondContact CH2-O 3.34Å; W119-R135 VanDerWaalsContact CZ3-O 3.31Å; W119-R135 WeakPolarHBondContact CZ3-O 3.33Å; W119-R135 CarbonylContact O-C 3.47Å; W119-R135 WeakPolarHBondContact O-CA 3.42Å; R135-G139 PolarHBondContact NH2-O 3Å; R135-R141 PolarHBondContact NE-O 2.84Å; R135-R141 PolarHBondContact NH2-O 2.92Å; R135-L143 HydrophobicContact CG-CB 3.87Å; R135-L143 HydrophobicContact CG-CD2 4.48Å; R135-E172 IonicContact CZ-OE1 3.4Å; R135-E172 IonicContact NH1-OE1 3.84Å; R135-E172 PolarHBondContact NH1-OE1 3.26Å; R135-E172 IonicContact NH2-OE1 3.77Å; R135-E172 PolarHBondContact NH2-OE1 3.15Å; R135-V173 WeakPolarHBondContact CD-O 3.41Å; R135-V173 PolarHBondContact NH1-O 2.95Å
136D98Very high96.9Very high1 Ų116.5 Ų16.51%0.0059%0.094CC..  trans-59162.617475.992.1000111.8W119 F138 G139 R140W119-D136 HydrophobicContact CD2-CB 3.68Å; W119-D136 VanDerWaalsContact CE2-CA 3.48Å; W119-D136 HydrophobicContact CE3-CB 4.36Å; W119-D136 VanDerWaalsContact CE3-N 3.33Å; W119-D136 HydrophobicContact CG-CB 3.8Å; W119-D136 HydrophobicContact CZ2-CB 4.11Å; W119-D136 PolarHBondContact N-OD2 3.48Å; W119-D136 VanDerWaalsContact N-OD2 3.12Å; W119-D136 PolarHBondContact O-N 2.82Å; D136-F138 PolarHBondContact O-N 2.68Å; D136-F138 PolarHBondContact OD1-N 2.64Å; D136-G139 PolarHBondContact O-N 3.44Å; D136-G139 PolarHBondContact OD1-N 3.31Å; D136-R140 IonicContact OD1-CZ 3.43Å; D136-R140 VanDerWaalsContact OD1-CZ 3.24Å; D136-R140 IonicContact OD1-NE 3.54Å; D136-R140 PolarHBondContact OD1-NE 3.32Å; D136-R140 IonicContact OD1-NH2 2.79Å; D136-R140 PolarHBondContact OD1-NH2 2.82Å; D136-R140 WeakPolarHBondContact OD2-CB 3.34Å; D136-R140 PolarHBondContact OD2-N 2.92Å; D136-R140 IonicContact OD2-NE 2.68Å
137F96.6Very high96.6Very high43 Ų4315.8 Ų15.819%0.1899%0.087CC..THydrogen-bonded Turntrans-50.8-35.3-175.4176.5-108.1000114.3W199 K239 P240 V241F137-W199 HydrophobicContact CB-CD2 4.47Å; F137-W199 HydrophobicContact CB-CZ2 4.31Å; F137-W199 HydrophobicContact CD2-CB 4.23Å; F137-W199 HydrophobicContact CD2-CD2 4.06Å; F137-W199 AromaticContact CD2-CG 3.89Å; F137-W199 HydrophobicContact CD2-CG 3.89Å; F137-W199 HydrophobicContact CE2-CB 4.44Å; F137-K239 HydrophobicContact CD2-CG 4.13Å; F137-K239 HydrophobicContact CE2-CB 4.27Å; F137-K239 HydrophobicContact CE2-CD 3.86Å; F137-K239 HydrophobicContact CE2-CG 3.63Å; F137-K239 HydrophobicContact CZ-CD 4.28Å; F137-K239 HydrophobicContact CZ-CG 4.32Å; F137-P240 HydrophobicContact CB-CG 3.7Å; F137-P240 HydrophobicContact CD1-CG 4.2Å; F137-P240 HydrophobicContact CG-CG 4Å; F137-V241 HydrophobicContact CD1-CG2 4.23Å; F137-V241 HydrophobicContact CE1-CG2 3.53Å; F137-V241 HydrophobicContact CZ-CG2 4.03Å
138F96.8Very high96Very high15 Ų1511.4 Ų11.47%0.0666%0.056CC..THydrogen-bonded Turntrans-91.1-12178.6-58.4-67.2000113.1D136 R140 V241 S530 L534 E555 V558D136-F138 PolarHBondContact O-N 2.68Å; D136-F138 PolarHBondContact OD1-N 2.64Å; F138-R140 HydrophobicContact CB-CG 3.97Å; F138-V241 HydrophobicContact CE2-CG1 4.5Å; F138-V241 HydrophobicContact CZ-CG1 3.8Å; F138-S530 WeakPolarHBondContact O-CA 3.32Å; F138-S530 WeakPolarHBondContact O-CB 3.47Å; F138-L534 HydrophobicContact CB-CD1 4.19Å; F138-L534 WeakPolarHBondContact O-CD1 3.2Å; F138-E555 HydrophobicContact CE2-CG 4.29Å; F138-V558 HydrophobicContact CE1-CB 4.44Å; F138-V558 HydrophobicContact CE1-CG1 3.99Å; F138-V558 HydrophobicContact CE1-CG2 4.03Å; F138-V558 HydrophobicContact CE2-CG2 4.35Å; F138-V558 HydrophobicContact CZ-CB 3.89Å; F138-V558 HydrophobicContact CZ-CG1 3.85Å; F138-V558 HydrophobicContact CZ-CG2 3.6Å
139G97Very high94.9Very high0 Ų014.6 Ų14.60%07%0.07CC..  trans64.244.5-17200000112.5R135 D136 R141 L534R135-G139 PolarHBondContact NH2-O 3Å; D136-G139 PolarHBondContact O-N 3.44Å; D136-G139 PolarHBondContact OD1-N 3.31Å; G139-R141 VanDerWaalsContact C-N 3.31Å; G139-R141 PolarHBondContact O-N 2.99Å; G139-L534 VanDerWaalsContact O-CB 3.25Å; G139-L534 WeakPolarHBondContact O-CB 3.38Å
140R97.4Very high93.6Very high1 Ų120.5 Ų20.50%0.00410%0.102CC..  trans-69.7-26.8-177.6-75.5163.6-67.7-175.60.4113.1G117 P118 D136 F138 L534 F550 L553 E555G117-R140 VanDerWaalsContact C-NH2 3.31Å; G117-R140 PolarHBondContact O-NH2 2.94Å; P118-R140 HydrophobicContact CB-CB 3.51Å; P118-R140 HydrophobicContact CB-CG 4.36Å; D136-R140 IonicContact OD1-CZ 3.43Å; D136-R140 VanDerWaalsContact OD1-CZ 3.24Å; D136-R140 IonicContact OD1-NE 3.54Å; D136-R140 PolarHBondContact OD1-NE 3.32Å; D136-R140 IonicContact OD1-NH2 2.79Å; D136-R140 PolarHBondContact OD1-NH2 2.82Å; D136-R140 WeakPolarHBondContact OD2-CB 3.34Å; D136-R140 PolarHBondContact OD2-N 2.92Å; D136-R140 IonicContact OD2-NE 2.68Å; F138-R140 HydrophobicContact CB-CG 3.97Å; R140-L534 HydrophobicContact CG-CD1 4.02Å; R140-L534 HydrophobicContact CG-CD2 4.41Å; R140-F550 HydrophobicContact CB-CD2 4.01Å; R140-F550 HydrophobicContact CB-CE2 3.9Å; R140-F550 HydrophobicContact CG-CD2 3.81Å; R140-F550 HydrophobicContact CG-CE2 4.13Å; R140-F550 HydrophobicContact CG-CG 4.41Å; R140-L553 HydrophobicContact CG-CD1 4.37Å; R140-L553 PolarHBondContact NH1-O 3.34Å; R140-E555 IonicContact CZ-OE1 2.81Å; R140-E555 VanDerWaalsContact CZ-OE1 3.26Å; R140-E555 IonicContact NH1-OE1 2.69Å; R140-E555 PolarHBondContact NH1-OE1 3.17Å; R140-E555 IonicContact NH1-OE2 3.67Å; R140-E555 PolarHBondContact NH1-OE2 2.99Å; R140-E555 IonicContact NH2-OE1 3.78Å; R140-E555 PolarHBondContact NH2-OE1 2.78Å
141R97.7Very high92.2Very high0 Ų017.8 Ų17.80%09%0.092CC..SBendtrans-105.3135.4175-63.5-69.6176.3-131.2-9110.3N76 P118 R135 G139 D538 E547 A548N76-R141 VanDerWaalsContact O-CG 3.3Å; N76-R141 WeakPolarHBondContact O-CG 3.42Å; P118-R141 HydrophobicContact CB-CG 4.07Å; R135-R141 PolarHBondContact NE-O 2.84Å; R135-R141 PolarHBondContact NH2-O 2.92Å; G139-R141 VanDerWaalsContact C-N 3.31Å; G139-R141 PolarHBondContact O-N 2.99Å; R141-D538 WeakPolarHBondContact CD-OD1 3.3Å; R141-D538 IonicContact CZ-OD1 3.96Å; R141-D538 IonicContact NH1-OD1 3.7Å; R141-D538 PolarHBondContact NH1-OD1 2.72Å; R141-E547 IonicContact CZ-OE2 2.79Å; R141-E547 IonicContact NE-OE2 3.9Å; R141-E547 IonicContact NH2-OE1 2.74Å; R141-E547 IonicContact NH2-OE2 2.67Å; R141-E547 PolarHBondContact NH2-OE2 3.03Å; R141-A548 PolarHBondContact NH1-O 3.18Å; R141-A548 PolarHBondContact NH2-O 2.91Å
142S97.3Very high91.2Very high0 Ų022.9 Ų22.90%011%0.114CC..  trans-71.8143.8179.3-170.60000111S120 S158 E172 D538 R539S120-S142 PolarHBondContact OG-O 2.73Å; S142-S158 WeakPolarHBondContact CB-O 3.42Å; S142-E172 PolarHBondContact OG-OE1 3.06Å; S142-D538 PolarHBondContact N-OD2 2.76Å; S142-R539 PolarHBondContact OG-NH1 2.67Å
143L98.2Very high90.6Very high0 Ų023.3 Ų23.30%012%0.117CC..  trans-148.8127.5164.9-173.166.9000106.7I4 I122 F133 R135 L156 E172 V173I4-L143 HydrophobicContact CD1-CD1 4.35Å; I122-L143 HydrophobicContact CD1-CD1 4.41Å; I122-L143 HydrophobicContact CG1-CD1 4.44Å; F133-L143 HydrophobicContact CB-CD2 4.24Å; F133-L143 HydrophobicContact CD2-CD2 4.22Å; R135-L143 HydrophobicContact CG-CB 3.87Å; R135-L143 HydrophobicContact CG-CD2 4.48Å; L143-L156 HydrophobicContact CD1-CB 4.45Å; L143-L156 HydrophobicContact CD2-CD2 4.48Å; L143-L156 HydrophobicContact CG-CD2 4.49Å; L143-E172 PolarHBondContact N-OE1 2.93Å; L143-V173 HydrophobicContact CB-CB 4.3Å; L143-V173 HydrophobicContact CB-CG2 4.23Å; L143-V173 HydrophobicContact CD2-CB 4.37Å; L143-V173 HydrophobicContact CD2-CG1 4.48Å; L143-V173 HydrophobicContact CD2-CG2 4.06Å; L143-V173 HydrophobicContact CG-CB 4.36Å; L143-V173 HydrophobicContact CG-CG2 3.84Å; L143-V173 WeakPolarHBondContact O-CB 3.39Å; L143-V173 WeakPolarHBondContact O-CG2 3.34Å; L143-V173 PolarHBondContact O-N 3.22Å
144L96.9Very high90.2Very high0 Ų023.4 Ų23.40%012%0.117CC..EExtended strand (participates in β ladder)trans-113.1146.4-179.6-56.9179.3000109.1L156 S157 G160 W170 Q171 E172 R539L144-L156 CarbonylContact O-C 3.58Å; L144-L156 VanDerWaalsContact O-CA 3.28Å; L144-L156 WeakPolarHBondContact O-CA 3.4Å; L144-S157 WeakPolarHBondContact CA-O 3.29Å; L144-S157 WeakPolarHBondContact CB-O 3.31Å; L144-S157 PolarHBondContact N-O 2.9Å; L144-S157 PolarHBondContact O-N 2.74Å; L144-G160 VanDerWaalsContact CD1-N 3.29Å; L144-W170 HydrophobicContact CB-CD2 4.44Å; L144-W170 HydrophobicContact CB-CE3 3.56Å; L144-W170 HydrophobicContact CB-CZ3 4.18Å; L144-W170 HydrophobicContact CD1-CB 4.13Å; L144-W170 HydrophobicContact CD1-CD2 4.42Å; L144-W170 HydrophobicContact CD1-CE3 4.25Å; L144-W170 HydrophobicContact CD1-CG 4.41Å; L144-Q171 CarbonylContact C-O 3.5Å; L144-Q171 WeakPolarHBondContact CA-O 3.41Å; L144-E172 HydrophobicContact CD2-CB 4.21Å; L144-E172 HydrophobicContact CD2-CG 4.39Å; L144-E172 VanDerWaalsContact CD2-OE2 3.32Å; L144-E172 WeakPolarHBondContact CD2-OE2 3.27Å; L144-R539 VanDerWaalsContact CD2-NH1 3.29Å
145W95.4Very high90Very high5 Ų523.9 Ų23.92%0.01912%0.121CC..EExtended strand (participates in β ladder)trans-108.1153.9161.756.245.7000110.5F133 F147 F154 C155 L156 Q171 V173 P174 F179 L194 I218 L222F133-W145 HydrophobicContact CE2-CE3 4.08Å; F133-W145 HydrophobicContact CE2-CZ3 4.36Å; W145-F147 HydrophobicContact CB-CE2 4.12Å; W145-F147 HydrophobicContact CB-CZ 4.2Å; W145-F147 AromaticContact CD1-CE2 3.38Å; W145-F147 AromaticContact CD2-CE2 3.93Å; W145-F147 HydrophobicContact CD2-CE2 3.93Å; W145-F147 HydrophobicContact CD2-CZ 4.09Å; W145-F147 HydrophobicContact CE3-CZ 4.48Å; W145-F147 HydrophobicContact CG-CD2 4.48Å; W145-F147 AromaticContact CG-CE2 3.58Å; W145-F147 HydrophobicContact CG-CE2 3.58Å; W145-F147 AromaticContact CG-CZ 3.94Å; W145-F147 HydrophobicContact CG-CZ 3.94Å; W145-F147 AromaticContact NE1-CE2 3.66Å; W145-F154 HydrophobicContact CB-CE2 4.04Å; W145-C155 CarbonylContact C-O 3.58Å; W145-C155 VanDerWaalsContact CA-O 3.26Å; W145-C155 WeakPolarHBondContact CA-O 3.2Å; W145-L156 HydrophobicContact CB-CD2 4.03Å; W145-Q171 PolarHBondContact N-O 2.98Å; W145-Q171 PolarHBondContact O-N 3.39Å; W145-V173 HydrophobicContact CB-CG2 4.18Å; W145-V173 HydrophobicContact CD2-CG2 3.95Å; W145-V173 HydrophobicContact CE3-CB 4.22Å; W145-V173 HydrophobicContact CE3-CG1 4.15Å; W145-V173 HydrophobicContact CE3-CG2 3.65Å; W145-V173 HydrophobicContact CG-CG2 4.21Å; W145-V173 HydrophobicContact CZ3-CB 4.46Å; W145-V173 HydrophobicContact CZ3-CG1 4.05Å; W145-V173 HydrophobicContact CZ3-CG2 4.36Å; W145-P174 HydrophobicContact CH2-CG 3.95Å; W145-P174 HydrophobicContact CZ2-CG 4.3Å; W145-F179 HydrophobicContact CH2-CE1 4.5Å; W145-F179 HydrophobicContact CH2-CZ 4.37Å; W145-F179 HydrophobicContact CZ3-CE1 4.3Å; W145-F179 HydrophobicContact CZ3-CE2 4.43Å; W145-F179 HydrophobicContact CZ3-CZ 4.23Å; W145-L194 HydrophobicContact CE3-CD1 4.37Å; W145-L194 HydrophobicContact CH2-CD1 4.2Å; W145-L194 HydrophobicContact CZ3-CD1 3.9Å; W145-I218 HydrophobicContact CH2-CG2 3.93Å; W145-I218 HydrophobicContact CZ2-CG2 4.34Å; W145-L222 HydrophobicContact CZ2-CD2 3.82Å
146H92.3Very high90Very high19 Ų1923.9 Ų23.99%0.08812%0.121CC..EExtended strand (participates in β ladder)trans-142.1126.9171.5171.6-97.9000108.9S148 C155 N168 W170H146-S148 WeakPolarHBondContact CE1-CB 3.49Å; H146-S148 PolarHBondContact CE1-OG 3.24Å; H146-S148 VanDerWaalsContact CE1-OG 3.26Å; H146-C155 HydrophobicContact CB-CB 4.43Å; H146-C155 PolarHBondContact N-O 2.87Å; H146-C155 PolarHBondContact O-N 3.33Å; H146-N168 PolarHBondContact CD2-O 3.34Å; H146-N168 PolarHBondContact NE2-O 3.18Å; H146-W170 HydrophobicContact CB-CD2 3.64Å; H146-W170 HydrophobicContact CB-CE3 3.42Å; H146-W170 VanDerWaalsContact CB-CE3 3.42Å; H146-W170 HydrophobicContact CB-CG 4.31Å; H146-W170 HydrophobicContact CB-CH2 3.99Å; H146-W170 HydrophobicContact CB-CZ2 4.15Å; H146-W170 HydrophobicContact CB-CZ3 3.61Å
147F89.1Confident90Very high8 Ų823.8 Ų23.84%0.03512%0.121CC..EExtended strand (participates in β ladder)trans-110.7120179.2-57.8-78.9000107.9W145 F154 I192 L194 L222 P223 F225 V226W145-F147 HydrophobicContact CB-CE2 4.12Å; W145-F147 HydrophobicContact CB-CZ 4.2Å; W145-F147 AromaticContact CD1-CE2 3.38Å; W145-F147 AromaticContact CD2-CE2 3.93Å; W145-F147 HydrophobicContact CD2-CE2 3.93Å; W145-F147 HydrophobicContact CD2-CZ 4.09Å; W145-F147 HydrophobicContact CE3-CZ 4.48Å; W145-F147 HydrophobicContact CG-CD2 4.48Å; W145-F147 AromaticContact CG-CE2 3.58Å; W145-F147 HydrophobicContact CG-CE2 3.58Å; W145-F147 AromaticContact CG-CZ 3.94Å; W145-F147 HydrophobicContact CG-CZ 3.94Å; W145-F147 AromaticContact NE1-CE2 3.66Å; F147-F154 AromaticContact CD1-CD2 3.67Å; F147-F154 HydrophobicContact CD1-CD2 3.67Å; F147-F154 HydrophobicContact CD1-CE2 4.31Å; F147-F154 AromaticContact CE1-CD2 3.31Å; F147-F154 HydrophobicContact CE1-CD2 3.31Å; F147-F154 AromaticContact CE1-CE2 3.54Å; F147-F154 HydrophobicContact CE1-CE2 3.54Å; F147-F154 HydrophobicContact CE1-CG 4.46Å; F147-F154 HydrophobicContact CZ-CD2 4.1Å; F147-F154 AromaticContact CZ-CE2 3.89Å; F147-F154 HydrophobicContact CZ-CE2 3.89Å; F147-I192 HydrophobicContact CD1-CD1 3.61Å; F147-I192 HydrophobicContact CE1-CD1 3.89Å; F147-I192 HydrophobicContact CE1-CG2 4.23Å; F147-L194 HydrophobicContact CZ-CD1 4.28Å; F147-L222 HydrophobicContact CD2-CD2 4.23Å; F147-L222 HydrophobicContact CE2-CD2 3.48Å; F147-L222 VanDerWaalsContact CE2-CD2 3.48Å; F147-L222 HydrophobicContact CZ-CD2 4.11Å; F147-P223 HydrophobicContact CB-CG 4.01Å; F147-P223 HydrophobicContact CD2-CG 4.31Å; F147-P223 HydrophobicContact CG-CG 4.4Å; F147-F225 HydrophobicContact CB-CE2 3.93Å; F147-F225 HydrophobicContact CB-CZ 3.84Å; F147-F225 HydrophobicContact CD1-CE2 4.45Å; F147-V226 HydrophobicContact CD1-CG2 3.65Å; F147-V226 HydrophobicContact CD2-CG2 4.33Å; F147-V226 HydrophobicContact CE1-CG1 4Å; F147-V226 HydrophobicContact CE1-CG2 3.84Å; F147-V226 HydrophobicContact CE2-CG2 4.5Å; F147-V226 HydrophobicContact CG-CG2 3.92Å; F147-V226 HydrophobicContact CZ-CG1 3.94Å; F147-V226 HydrophobicContact CZ-CG2 4.28Å
148S81.3Confident90.1Very high19 Ų1921.8 Ų21.813%0.13311%0.112CC..EExtended strand (participates in β ladder)trans-134.3170-178.847.70000113H146 L150 G151 S153H146-S148 WeakPolarHBondContact CE1-CB 3.49Å; H146-S148 PolarHBondContact CE1-OG 3.24Å; H146-S148 VanDerWaalsContact CE1-OG 3.26Å; S148-L150 VanDerWaalsContact C-N 3.31Å; S148-L150 PolarHBondContact O-N 2.78Å; S148-G151 PolarHBondContact O-N 3.39Å; S148-S153 PolarHBondContact N-O 2.98Å; S148-S153 VanDerWaalsContact N-O 3.11Å; S148-S153 PolarHBondContact O-N 3.47Å; S148-S153 PolarHBondContact O-OG 3.43Å; S148-S153 PolarHBondContact OG-OG 2.88Å
149N72.9Confident90Very high101 Ų10121.1 Ų21.154%0.5411%0.109SC..G310 helixtrans58.739.8174.4-58.6-26.9000112.7G151 K152 S153N149-G151 VanDerWaalsContact C-N 3.3Å; N149-G151 PolarHBondContact O-N 3.3Å; N149-K152 HydrophobicContact CB-CB 3.83Å; N149-K152 HydrophobicContact CB-CD 4.43Å; N149-K152 WeakPolarHBondContact O-CB 3.35Å; N149-K152 WeakPolarHBondContact O-CG 3.49Å; N149-K152 PolarHBondContact O-N 3.33Å; N149-K152 VanDerWaalsContact O-N 3.11Å; N149-S153 PolarHBondContact ND2-OG 2.73Å
150L70.1Confident89.7Confident158 Ų15821.1 Ų21.183%0.82711%0.109SC*.G310 helixtrans52.845178.1-60.7166.1000112.7S148S148-L150 VanDerWaalsContact C-N 3.31Å; S148-L150 PolarHBondContact O-N 2.78Å
151G66.9Low89.2Confident1 Ų121.6 Ų21.61%0.0111%0.112CC..G310 helixtrans87.33.7178.800000115.3S148 N149S148-G151 PolarHBondContact O-N 3.39Å; N149-G151 VanDerWaalsContact C-N 3.3Å; N149-G151 PolarHBondContact O-N 3.3Å
152K76.9Confident88.1Confident107 Ų10723.9 Ų23.947%0.46512%0.122SC..THydrogen-bonded Turntrans-77.8-20.9175.2-64.1176.1-178.1-173.30113.5N9 F10 N149N9-K152 PolarHBondContact OD1-O 3.38Å; F10-K152 PolarHBondContact N-O 2.88Å; N149-K152 HydrophobicContact CB-CB 3.83Å; N149-K152 HydrophobicContact CB-CD 4.43Å; N149-K152 WeakPolarHBondContact O-CB 3.35Å; N149-K152 WeakPolarHBondContact O-CG 3.49Å; N149-K152 PolarHBondContact O-N 3.33Å; N149-K152 VanDerWaalsContact O-N 3.11Å
153S85.7Confident86.8Confident11 Ų1125.5 Ų25.58%0.07713%0.132CC..EExtended strand (participates in β ladder)trans-141.5141-177.956.60000112.6V8 S148 N149V8-S153 CarbonylContact O-C 3.12Å; V8-S153 VanDerWaalsContact O-CA 3.27Å; V8-S153 WeakPolarHBondContact O-CA 3.34Å; S148-S153 PolarHBondContact N-O 2.98Å; S148-S153 VanDerWaalsContact N-O 3.11Å; S148-S153 PolarHBondContact O-N 3.47Å; S148-S153 PolarHBondContact O-OG 3.43Å; S148-S153 PolarHBondContact OG-OG 2.88Å; N149-S153 PolarHBondContact ND2-OG 2.73Å
154F91.2Very high84.9Confident1 Ų130.9 Ų30.90%0.00417%0.17CC..EExtended strand (participates in β ladder)trans-129.6133177.1167.1-113.3000108.7V8 F10 L131 F133 W145 F147 L156 I181 I192V8-F154 HydrophobicContact CB-CB 4.37Å; V8-F154 HydrophobicContact CB-CD1 4.32Å; V8-F154 HydrophobicContact CG2-CD1 4.03Å; V8-F154 PolarHBondContact N-O 3.34Å; V8-F154 PolarHBondContact O-N 3.04Å; F10-F154 HydrophobicContact CE2-CB 4.24Å; L131-F154 HydrophobicContact CD2-CD1 4.29Å; L131-F154 HydrophobicContact CD2-CE1 3.79Å; F133-F154 HydrophobicContact CE1-CE1 4.5Å; F133-F154 HydrophobicContact CE1-CZ 4.05Å; F133-F154 AromaticContact CZ-CZ 4Å; F133-F154 HydrophobicContact CZ-CZ 4Å; W145-F154 HydrophobicContact CB-CE2 4.04Å; F147-F154 AromaticContact CD1-CD2 3.67Å; F147-F154 HydrophobicContact CD1-CD2 3.67Å; F147-F154 HydrophobicContact CD1-CE2 4.31Å; F147-F154 AromaticContact CE1-CD2 3.31Å; F147-F154 HydrophobicContact CE1-CD2 3.31Å; F147-F154 AromaticContact CE1-CE2 3.54Å; F147-F154 HydrophobicContact CE1-CE2 3.54Å; F147-F154 HydrophobicContact CE1-CG 4.46Å; F147-F154 HydrophobicContact CZ-CD2 4.1Å; F147-F154 AromaticContact CZ-CE2 3.89Å; F147-F154 HydrophobicContact CZ-CE2 3.89Å; F154-L156 HydrophobicContact CE1-CD1 3.68Å; F154-L156 HydrophobicContact CE1-CD2 4.38Å; F154-L156 HydrophobicContact CE1-CG 3.65Å; F154-L156 HydrophobicContact CE2-CD2 4.22Å; F154-L156 HydrophobicContact CE2-CG 4.23Å; F154-L156 HydrophobicContact CZ-CD1 3.71Å; F154-L156 HydrophobicContact CZ-CD2 3.62Å; F154-L156 HydrophobicContact CZ-CG 3.39Å; F154-I181 HydrophobicContact CD1-CD1 3.95Å; F154-I181 HydrophobicContact CE1-CD1 3.44Å; F154-I181 VanDerWaalsContact CE1-CD1 3.44Å; F154-I181 HydrophobicContact CE2-CD1 4.13Å; F154-I181 HydrophobicContact CG-CD1 4.47Å; F154-I181 HydrophobicContact CZ-CD1 3.5Å; F154-I192 HydrophobicContact CB-CD1 4.07Å
155C94.6Very high83.1Confident11 Ų1133.3 Ų33.37%0.07420%0.195CC..EExtended strand (participates in β ladder)trans-131.3133.1177.9-168.20000110.7C6 W145 H146 W170C6-C155 CarbonylContact O-C 3.55Å; C6-C155 WeakPolarHBondContact O-CA 3.33Å; W145-C155 CarbonylContact C-O 3.58Å; W145-C155 VanDerWaalsContact CA-O 3.26Å; W145-C155 WeakPolarHBondContact CA-O 3.2Å; H146-C155 HydrophobicContact CB-CB 4.43Å; H146-C155 PolarHBondContact N-O 2.87Å; H146-C155 PolarHBondContact O-N 3.33Å; C155-W170 HydrophobicContact CB-CH2 4.14Å; C155-W170 HydrophobicContact CB-CZ3 4.44Å
156L97.8Very high81.1Confident0 Ų039.9 Ų39.90%023%0.23CC..EExtended strand (participates in β ladder)trans-107.4133.7167.3-70.8166.9000108.6C5 C6 I122 L131 F133 L143 L144 W145 F154 V173C5-L156 CarbonylContact C-O 3.55Å; C5-L156 WeakPolarHBondContact CA-O 3.38Å; C5-L156 PolarHBondContact SG-O 3.46Å; C6-L156 HydrophobicContact CB-CB 4.48Å; C6-L156 PolarHBondContact N-O 2.83Å; C6-L156 PolarHBondContact O-N 2.82Å; I122-L156 HydrophobicContact CD1-CB 3.69Å; I122-L156 HydrophobicContact CD1-CD1 4.36Å; I122-L156 HydrophobicContact CG1-CB 4.3Å; I122-L156 HydrophobicContact CG1-CD1 4.17Å; I122-L156 HydrophobicContact CG2-CD1 4.31Å; L131-L156 HydrophobicContact CD2-CD1 4.23Å; F133-L156 HydrophobicContact CB-CD1 3.78Å; F133-L156 HydrophobicContact CD1-CD1 3.57Å; F133-L156 HydrophobicContact CD2-CD1 4.02Å; F133-L156 HydrophobicContact CD2-CD2 3.75Å; F133-L156 HydrophobicContact CE1-CD1 4.1Å; F133-L156 HydrophobicContact CE2-CD1 4.49Å; F133-L156 HydrophobicContact CE2-CD2 3.85Å; F133-L156 HydrophobicContact CG-CD1 3.51Å; F133-L156 HydrophobicContact CG-CD2 4.15Å; F133-L156 HydrophobicContact CG-CG 4.49Å; F133-L156 HydrophobicContact CZ-CD2 4.33Å; L143-L156 HydrophobicContact CD1-CB 4.45Å; L143-L156 HydrophobicContact CD2-CD2 4.48Å; L143-L156 HydrophobicContact CG-CD2 4.49Å; L144-L156 CarbonylContact O-C 3.58Å; L144-L156 VanDerWaalsContact O-CA 3.28Å; L144-L156 WeakPolarHBondContact O-CA 3.4Å; W145-L156 HydrophobicContact CB-CD2 4.03Å; F154-L156 HydrophobicContact CE1-CD1 3.68Å; F154-L156 HydrophobicContact CE1-CD2 4.38Å; F154-L156 HydrophobicContact CE1-CG 3.65Å; F154-L156 HydrophobicContact CE2-CD2 4.22Å; F154-L156 HydrophobicContact CE2-CG 4.23Å; F154-L156 HydrophobicContact CZ-CD1 3.71Å; F154-L156 HydrophobicContact CZ-CD2 3.62Å; F154-L156 HydrophobicContact CZ-CG 3.39Å; L156-V173 HydrophobicContact CD2-CG2 4.07Å
157S97.8Very high79.2Confident0 Ų043.2 Ų43.20%026%0.261CS..EExtended strand (participates in β ladder)trans-152.6142.5177.4-175.90000112.4I4 L144 V159I4-S157 CarbonylContact O-C 3.57Å; I4-S157 WeakPolarHBondContact O-CA 3.02Å; L144-S157 WeakPolarHBondContact CA-O 3.29Å; L144-S157 WeakPolarHBondContact CB-O 3.31Å; L144-S157 PolarHBondContact N-O 2.9Å; L144-S157 PolarHBondContact O-N 2.74Å; S157-V159 WeakPolarHBondContact CB-O 3.15Å; S157-V159 PolarHBondContact O-N 2.87Å; S157-V159 PolarHBondContact OG-N 3.4Å; S157-V159 PolarHBondContact OG-O 3.2Å
158S97.8Very high78Confident0 Ų046 Ų460%028%0.276CS..SBendtrans-66.7-15.6172.458.30000114.4G3 I4 L27 R30 S142G3-S158 WeakPolarHBondContact CA-OG 3.48Å; I4-S158 PolarHBondContact N-OG 3.14Å; I4-S158 PolarHBondContact O-N 2.85Å; I4-S158 PolarHBondContact O-OG 3.33Å; L27-S158 WeakPolarHBondContact CD2-OG 3.17Å; R30-S158 PolarHBondContact NE-OG 3.46Å; S142-S158 WeakPolarHBondContact CB-O 3.42Å
159V95.9Very high78Confident1 Ų148.7 Ų48.71%0.00629%0.286CS..SBendtrans-151.2141.5177.459.70000109.6L23 N26 L27 S157 L448 R539L23-V159 WeakPolarHBondContact CD1-O 3.35Å; N26-V159 HydrophobicContact CB-CB 4.48Å; N26-V159 HydrophobicContact CB-CG1 3.61Å; N26-V159 HydrophobicContact CB-CG2 4Å; L27-V159 HydrophobicContact CD2-CG1 3.94Å; L27-V159 HydrophobicContact CG-CG1 4.14Å; S157-V159 WeakPolarHBondContact CB-O 3.15Å; S157-V159 PolarHBondContact O-N 2.87Å; S157-V159 PolarHBondContact OG-N 3.4Å; S157-V159 PolarHBondContact OG-O 3.2Å; V159-L448 HydrophobicContact CG2-CD2 3.85Å; V159-R539 HydrophobicContact CB-CG 4.47Å; V159-R539 HydrophobicContact CG2-CG 4.42Å
160G90.8Very high78.9Confident0 Ų044.4 Ų44.40%026%0.262CS..  trans-94.7-177.9-178.300000112.4N26 L144N26-G160 PolarHBondContact ND2-O 3.25Å; L144-G160 VanDerWaalsContact CD1-N 3.29Å
161T86.4Confident79.9Confident11 Ų1139.3 Ų39.37%0.06724%0.235CC..  trans-124155.9162.554.50000108.3D22 L23 T163 W170D22-T161 HydrophobicContact CB-CG2 3.69Å; L23-T161 VanDerWaalsContact CA-CG2 3.44Å; L23-T161 HydrophobicContact CB-CG2 3.72Å; L23-T161 HydrophobicContact CD1-CG2 4.27Å; L23-T161 VanDerWaalsContact N-CG2 3.32Å; T161-T163 PolarHBondContact O-N 3.45Å; T161-W170 PolarHBondContact O-NE1 3.33Å; T161-W170 VanDerWaalsContact O-NE1 3.12Å
162Q75.7Confident81.2Confident48 Ų4840.7 Ų40.722%0.22424%0.241CC..  trans-73.9124.7176.5-167.8161.212.700108.7H447 L627 I629Q162-H447 VanDerWaalsContact CB-ND1 3.31Å; Q162-H447 WeakPolarHBondContact CB-ND1 3.43Å; Q162-H447 PolarHBondContact N-ND1 2.93Å; Q162-L627 PolarHBondContact NE2-O 3.13Å; Q162-I629 HydrophobicContact CB-CD1 4.22Å; Q162-I629 HydrophobicContact CG-CD1 4.35Å
163T68.6Low82.1Confident34 Ų3435.6 Ų35.621%0.20922%0.218CC..  trans-106.6145.6179.947.40000109.8T161 N168T161-T163 PolarHBondContact O-N 3.45Å; T163-N168 VanDerWaalsContact CB-O 3.25Å; T163-N168 WeakPolarHBondContact CB-O 3.34Å; T163-N168 PolarHBondContact OG1-O 3.43Å
164S59.4Low82.5Confident114 Ų11436.6 Ų36.680%0.79723%0.225SC*.SBendtrans-79.7133.1172.148.60000110.3
165G58.5Low82.7Confident50 Ų5037.3 Ų37.352%0.51523%0.231SC..SBendtrans95146.4176.800000115.2A167G165-A167 VanDerWaalsContact C-N 3.34Å; G165-A167 PolarHBondContact O-N 3.12Å
166L53.8Low82.6Confident144 Ų14437.9 Ų37.975%0.75424%0.235SC*.G310 helixtrans-66.9-30.1-177.7-78.3152.4000113.5N168L166-N168 PolarHBondContact O-N 3.37Å
167A52.7Low82.5Confident89 Ų8937.9 Ų37.974%0.73624%0.235SC*.G310 helixtrans-83.2-5-173.800000114.9G165G165-A167 VanDerWaalsContact C-N 3.34Å; G165-A167 PolarHBondContact O-N 3.12Å
168N63.9Low82.5Confident65 Ų6537.9 Ų37.935%0.34824%0.235SC..G310 helixtrans-122.830.2-176.8-77.4-26.8000111.6H146 T163 L166H146-N168 PolarHBondContact CD2-O 3.34Å; H146-N168 PolarHBondContact NE2-O 3.18Å; T163-N168 VanDerWaalsContact CB-O 3.25Å; T163-N168 WeakPolarHBondContact CB-O 3.34Å; T163-N168 PolarHBondContact OG1-O 3.43Å; L166-N168 PolarHBondContact O-N 3.37Å
169Q80.9Confident82.5Confident76 Ų7637.9 Ų37.936%0.35524%0.235SC..  trans-82.6143.6-178-67.7-174.2-8.600111.4
170W90.7Very high82.6Confident11 Ų1138.8 Ų38.84%0.04224%0.238CC..  trans-65149.1165.2-67.887.3000109.2L23 L144 H146 C155 T161 P451L23-W170 HydrophobicContact CD1-CH2 4.45Å; L23-W170 HydrophobicContact CD1-CZ2 4.27Å; L23-W170 HydrophobicContact CD2-CH2 4.29Å; L23-W170 HydrophobicContact CD2-CZ2 4.25Å; L144-W170 HydrophobicContact CB-CD2 4.44Å; L144-W170 HydrophobicContact CB-CE3 3.56Å; L144-W170 HydrophobicContact CB-CZ3 4.18Å; L144-W170 HydrophobicContact CD1-CB 4.13Å; L144-W170 HydrophobicContact CD1-CD2 4.42Å; L144-W170 HydrophobicContact CD1-CE3 4.25Å; L144-W170 HydrophobicContact CD1-CG 4.41Å; H146-W170 HydrophobicContact CB-CD2 3.64Å; H146-W170 HydrophobicContact CB-CE3 3.42Å; H146-W170 VanDerWaalsContact CB-CE3 3.42Å; H146-W170 HydrophobicContact CB-CG 4.31Å; H146-W170 HydrophobicContact CB-CH2 3.99Å; H146-W170 HydrophobicContact CB-CZ2 4.15Å; H146-W170 HydrophobicContact CB-CZ3 3.61Å; C155-W170 HydrophobicContact CB-CH2 4.14Å; C155-W170 HydrophobicContact CB-CZ3 4.44Å; T161-W170 PolarHBondContact O-NE1 3.33Å; T161-W170 VanDerWaalsContact O-NE1 3.12Å; W170-P451 VanDerWaalsContact O-CB 3.31Å; W170-P451 WeakPolarHBondContact O-CB 3.43Å
171Q92.3Very high82.9Confident52 Ų5238.8 Ų38.824%0.24324%0.238CC..EExtended strand (participates in β ladder)trans-135.8148175.2-72173.5-20.200108.8L144 W145 V173 D221L144-Q171 CarbonylContact C-O 3.5Å; L144-Q171 WeakPolarHBondContact CA-O 3.41Å; W145-Q171 PolarHBondContact N-O 2.98Å; W145-Q171 PolarHBondContact O-N 3.39Å; Q171-V173 PolarHBondContact O-N 2.98Å; Q171-D221 PolarHBondContact NE2-O 2.87Å
172E93.8Very high83.3Confident29 Ų2940.7 Ų40.714%0.13625%0.248CC..EExtended strand (participates in β ladder)trans-72.5131178.8-161.282.2-147.300109.7R135 S142 L143 L144 P174 P451 R539R135-E172 IonicContact CZ-OE1 3.4Å; R135-E172 IonicContact NH1-OE1 3.84Å; R135-E172 PolarHBondContact NH1-OE1 3.26Å; R135-E172 IonicContact NH2-OE1 3.77Å; R135-E172 PolarHBondContact NH2-OE1 3.15Å; S142-E172 PolarHBondContact OG-OE1 3.06Å; L143-E172 PolarHBondContact N-OE1 2.93Å; L144-E172 HydrophobicContact CD2-CB 4.21Å; L144-E172 HydrophobicContact CD2-CG 4.39Å; L144-E172 VanDerWaalsContact CD2-OE2 3.32Å; L144-E172 WeakPolarHBondContact CD2-OE2 3.27Å; E172-P174 VanDerWaalsContact O-CD 3.29Å; E172-P174 WeakPolarHBondContact O-CD 3.33Å; E172-P451 HydrophobicContact CB-CG 4.31Å; E172-R539 IonicContact OE1-NH1 3.76Å; E172-R539 IonicContact OE2-CZ 2.61Å; E172-R539 IonicContact OE2-NH1 3.29Å; E172-R539 PolarHBondContact OE2-NH1 3.39Å; E172-R539 IonicContact OE2-NH2 3.64Å
173V95.9Very high84.3Confident0 Ų038.4 Ų38.40%024%0.238CC..PPolyproline II helixtrans-64.3121.9168-179.20000107.7F133 R135 L143 W145 L156 Q171 F179F133-V173 HydrophobicContact CD2-CG1 4.16Å; F133-V173 HydrophobicContact CE2-CG1 4.11Å; F133-V173 HydrophobicContact CE2-CG2 4.45Å; R135-V173 WeakPolarHBondContact CD-O 3.41Å; R135-V173 PolarHBondContact NH1-O 2.95Å; L143-V173 HydrophobicContact CB-CB 4.3Å; L143-V173 HydrophobicContact CB-CG2 4.23Å; L143-V173 HydrophobicContact CD2-CB 4.37Å; L143-V173 HydrophobicContact CD2-CG1 4.48Å; L143-V173 HydrophobicContact CD2-CG2 4.06Å; L143-V173 HydrophobicContact CG-CB 4.36Å; L143-V173 HydrophobicContact CG-CG2 3.84Å; L143-V173 WeakPolarHBondContact O-CB 3.39Å; L143-V173 WeakPolarHBondContact O-CG2 3.34Å; L143-V173 PolarHBondContact O-N 3.22Å; W145-V173 HydrophobicContact CB-CG2 4.18Å; W145-V173 HydrophobicContact CD2-CG2 3.95Å; W145-V173 HydrophobicContact CE3-CB 4.22Å; W145-V173 HydrophobicContact CE3-CG1 4.15Å; W145-V173 HydrophobicContact CE3-CG2 3.65Å; W145-V173 HydrophobicContact CG-CG2 4.21Å; W145-V173 HydrophobicContact CZ3-CB 4.46Å; W145-V173 HydrophobicContact CZ3-CG1 4.05Å; W145-V173 HydrophobicContact CZ3-CG2 4.36Å; L156-V173 HydrophobicContact CD2-CG2 4.07Å; Q171-V173 PolarHBondContact O-N 2.98Å; V173-F179 HydrophobicContact CG1-CD2 3.95Å; V173-F179 HydrophobicContact CG1-CE2 3.79Å
174P94.6Very high85.5Confident33 Ų3341.3 Ų41.321%0.21425%0.247CC..PPolyproline II helixtrans-61.5142.3-179.7-23.233.2000112.1W145 E172 S176 F179 I218W145-P174 HydrophobicContact CH2-CG 3.95Å; W145-P174 HydrophobicContact CZ2-CG 4.3Å; E172-P174 VanDerWaalsContact O-CD 3.29Å; E172-P174 WeakPolarHBondContact O-CD 3.33Å; P174-S176 PolarHBondContact O-N 3.26Å; P174-F179 HydrophobicContact CB-CZ 4.5Å; P174-F179 HydrophobicContact CG-CZ 4.42Å; P174-I218 HydrophobicContact CB-CD1 4.23Å; P174-I218 HydrophobicContact CB-CG1 4.32Å; P174-I218 HydrophobicContact CG-CD1 4.13Å; P174-I218 HydrophobicContact CG-CG1 3.88Å; P174-I218 HydrophobicContact CG-CG2 4.15Å
175A94.9Very high87Confident15 Ų1538.4 Ų38.412%0.12423%0.227CC..THydrogen-bonded Turntrans-79.837.4171.200000112.1
176S92.7Very high88.6Confident24 Ų2436.2 Ų36.217%0.16820%0.203CC..THydrogen-bonded Turntrans-87.1-14-177.255.60000113.4P174 P198 W199 I218P174-S176 PolarHBondContact O-N 3.26Å; S176-P198 VanDerWaalsContact O-CA 3.31Å; S176-P198 WeakPolarHBondContact O-CA 3.28Å; S176-W199 PolarHBondContact O-N 2.82Å; S176-I218 WeakPolarHBondContact OG-CD1 3.35Å
177G95.4Very high90.3Very high0 Ų029.6 Ų29.60%017%0.17CC..EExtended strand (participates in β ladder)trans157.8-154.5-178.600000112.3Y197G177-Y197 CarbonylContact C-O 3.59Å; G177-Y197 WeakPolarHBondContact CA-O 3.47Å
178L97.9Very high92Very high0 Ų031.2 Ų31.20%017%0.165CC..EExtended strand (participates in β ladder)trans-98.4147.1171.4-56.9-170.7000111.1L109 F112 W119 F121 Y197 L237L109-L178 HydrophobicContact CD2-CD1 3.99Å; L109-L178 HydrophobicContact CD2-CG 4.47Å; F112-L178 HydrophobicContact CB-CD1 4.04Å; F112-L178 HydrophobicContact CD2-CD1 3.76Å; F112-L178 HydrophobicContact CE2-CD1 4.47Å; F112-L178 HydrophobicContact CG-CD1 3.98Å; W119-L178 HydrophobicContact CH2-CD2 3.94Å; W119-L178 HydrophobicContact CZ3-CD2 4.05Å; F121-L178 HydrophobicContact CE1-CD1 4.33Å; F121-L178 HydrophobicContact CE1-CD2 3.5Å; F121-L178 HydrophobicContact CZ-CD1 4.07Å; F121-L178 HydrophobicContact CZ-CD2 3.89Å; L178-Y197 PolarHBondContact N-O 3.02Å; L178-Y197 PolarHBondContact O-N 3.39Å; L178-L237 HydrophobicContact CB-CD1 4.28Å; L178-L237 HydrophobicContact CD1-CD1 4.43Å; L178-L237 HydrophobicContact CD1-CD2 3.94Å; L178-L237 HydrophobicContact CD2-CD2 4.38Å; L178-L237 HydrophobicContact CG-CD1 3.8Å; L178-L237 HydrophobicContact CG-CD2 3.8Å; L178-L237 HydrophobicContact CG-CG 4.38Å
179F98.1Very high93.2Very high0 Ų031 Ų310%017%0.168CC..EExtended strand (participates in β ladder)trans-115.5146.8175.1-62.3-91000110W132 F133 W145 V173 P174 L194 Q195 L196 I218 V228W132-F179 WeakPolarHBondContact CA-O 3.16Å; F133-F179 HydrophobicContact CD1-CB 4.29Å; F133-F179 HydrophobicContact CD2-CB 4Å; F133-F179 HydrophobicContact CD2-CD2 4.34Å; F133-F179 HydrophobicContact CE1-CB 3.82Å; F133-F179 HydrophobicContact CE2-CB 3.49Å; F133-F179 VanDerWaalsContact CE2-CB 3.49Å; F133-F179 AromaticContact CE2-CD2 3.97Å; F133-F179 HydrophobicContact CE2-CD2 3.97Å; F133-F179 AromaticContact CE2-CG 3.89Å; F133-F179 HydrophobicContact CE2-CG 3.89Å; F133-F179 HydrophobicContact CG-CB 4.38Å; F133-F179 HydrophobicContact CZ-CB 3.4Å; F133-F179 VanDerWaalsContact CZ-CB 3.4Å; F133-F179 HydrophobicContact CZ-CG 4.13Å; F133-F179 PolarHBondContact N-O 3.44Å; F133-F179 PolarHBondContact O-N 2.83Å; W145-F179 HydrophobicContact CH2-CE1 4.5Å; W145-F179 HydrophobicContact CH2-CZ 4.37Å; W145-F179 HydrophobicContact CZ3-CE1 4.3Å; W145-F179 HydrophobicContact CZ3-CE2 4.43Å; W145-F179 HydrophobicContact CZ3-CZ 4.23Å; V173-F179 HydrophobicContact CG1-CD2 3.95Å; V173-F179 HydrophobicContact CG1-CE2 3.79Å; P174-F179 HydrophobicContact CB-CZ 4.5Å; P174-F179 HydrophobicContact CG-CZ 4.42Å; F179-L194 HydrophobicContact CD1-CB 4.21Å; F179-Q195 CarbonylContact C-O 3.17Å; F179-Q195 VanDerWaalsContact CA-O 3.3Å; F179-Q195 WeakPolarHBondContact CA-O 3.16Å; F179-L196 HydrophobicContact CD1-CB 4.44Å; F179-L196 HydrophobicContact CD1-CD1 4.14Å; F179-L196 HydrophobicContact CE1-CB 4.34Å; F179-L196 HydrophobicContact CE1-CD1 3.73Å; F179-L196 HydrophobicContact CE1-CG 4.48Å; F179-L196 HydrophobicContact CE2-CD1 4.29Å; F179-L196 HydrophobicContact CZ-CD1 3.81Å; F179-I218 HydrophobicContact CZ-CD1 4.31Å; F179-V228 HydrophobicContact CE1-CG1 4.46Å
180R97.7Very high93.4Very high19 Ų1933.1 Ų33.17%0.07217%0.173CC..EExtended strand (participates in β ladder)trans-130.8140172.4-174.4-174.577.1174.1-2.3110.9E105 Y130 L131 W132 Q195 Y197E105-R180 IonicContact OE1-CZ 2.69Å; E105-R180 IonicContact OE1-NH1 3.95Å; E105-R180 PolarHBondContact OE1-NH1 2.88Å; E105-R180 IonicContact OE1-NH2 3.19Å; Y130-R180 HydrophobicContact CG-CG 4.3Å; L131-R180 CarbonylContact O-C 3.59Å; L131-R180 WeakPolarHBondContact O-CA 3.41Å; W132-R180 HydrophobicContact CD2-CB 4.07Å; W132-R180 HydrophobicContact CD2-CG 3.97Å; W132-R180 HydrophobicContact CE3-CB 3.94Å; W132-R180 HydrophobicContact CE3-CG 4.33Å; W132-R180 HydrophobicContact CG-CG 4.41Å; W132-R180 HydrophobicContact CH2-CB 4.43Å; W132-R180 HydrophobicContact CH2-CG 4.49Å; W132-R180 HydrophobicContact CZ2-CG 4.15Å; W132-R180 HydrophobicContact CZ3-CB 4.13Å; R180-Q195 HydrophobicContact CB-CB 4.38Å; R180-Q195 PolarHBondContact N-O 3.03Å; R180-Q195 PolarHBondContact O-N 2.85Å; R180-Y197 HydrophobicContact CB-CE2 3.95Å
181I96.8Very high93.3Very high1 Ų134.4 Ų34.41%0.00518%0.184CC..EExtended strand (participates in β ladder)trans-119.9134.3168.9-59.3168.1000109Y130 L131 F133 F154 L183 I192 L194Y130-I181 WeakPolarHBondContact CA-O 3.33Å; L131-I181 PolarHBondContact N-O 2.92Å; L131-I181 PolarHBondContact O-N 3.2Å; F133-I181 HydrophobicContact CE1-CD1 3.77Å; F133-I181 HydrophobicContact CE1-CG1 4Å; F133-I181 HydrophobicContact CZ-CD1 4.22Å; F154-I181 HydrophobicContact CD1-CD1 3.95Å; F154-I181 HydrophobicContact CE1-CD1 3.44Å; F154-I181 VanDerWaalsContact CE1-CD1 3.44Å; F154-I181 HydrophobicContact CE2-CD1 4.13Å; F154-I181 HydrophobicContact CG-CD1 4.47Å; F154-I181 HydrophobicContact CZ-CD1 3.5Å; I181-L183 HydrophobicContact CB-CD2 4.33Å; I181-L183 HydrophobicContact CG2-CD2 3.86Å; I181-I192 HydrophobicContact CD1-CG2 3.96Å; I181-I192 HydrophobicContact CG1-CG2 4.31Å; I181-L194 HydrophobicContact CD1-CD2 3.59Å; I181-L194 HydrophobicContact CG1-CD2 3.58Å
182D95.9Very high93.3Very high51 Ų5132 Ų3227%0.27317%0.172SC..EExtended strand (participates in β ladder)trans-86.1102.5163.9-179-24.8000109.1Y130 K184 S185 T186Y130-D182 HydrophobicContact CD1-CB 4.05Å; Y130-D182 HydrophobicContact CE1-CB 3.89Å; D182-K184 VanDerWaalsContact C-N 3.26Å; D182-K184 PolarHBondContact O-N 3.26Å; D182-K184 WeakPolarHBondContact OD1-CB 3.32Å; D182-K184 PolarHBondContact OD1-N 3.47Å; D182-S185 VanDerWaalsContact CG-CB 3.41Å; D182-S185 PolarHBondContact O-N 3.12Å; D182-S185 PolarHBondContact OD1-N 2.98Å; D182-T186 WeakPolarHBondContact O-CB 3.23Å; D182-T186 PolarHBondContact O-N 3.26Å; D182-T186 PolarHBondContact O-OG1 2.96Å
183L95.4Very high93.3Very high0 Ų033.8 Ų33.80%018%0.182CC..Hα-helixtrans-65.7-32.1-174.7-61-174.5000112.3V8 F10 Y45 Y124 H129 L131 I181 A187V8-L183 HydrophobicContact CG1-CD2 4.09Å; V8-L183 HydrophobicContact CG2-CD2 4.44Å; F10-L183 HydrophobicContact CE1-CD2 4.25Å; F10-L183 HydrophobicContact CZ-CD2 4.24Å; Y45-L183 HydrophobicContact CD1-CB 3.81Å; Y45-L183 HydrophobicContact CD2-CB 4.29Å; Y45-L183 HydrophobicContact CD2-CD1 4.03Å; Y45-L183 HydrophobicContact CE1-CB 3.58Å; Y45-L183 HydrophobicContact CE2-CB 4.11Å; Y45-L183 HydrophobicContact CE2-CD1 3.58Å; Y45-L183 HydrophobicContact CG-CB 4.16Å; Y124-L183 HydrophobicContact CD2-CD1 4.08Å; Y124-L183 HydrophobicContact CE2-CD1 3.92Å; H129-L183 WeakPolarHBondContact O-CB 3.24Å; H129-L183 WeakPolarHBondContact O-CG 3.35Å; H129-L183 PolarHBondContact O-N 2.95Å; L131-L183 HydrophobicContact CB-CD1 4.23Å; L131-L183 HydrophobicContact CB-CD2 4.05Å; L131-L183 HydrophobicContact CB-CG 4.13Å; L131-L183 HydrophobicContact CD2-CD2 4.25Å; I181-L183 HydrophobicContact CB-CD2 4.33Å; I181-L183 HydrophobicContact CG2-CD2 3.86Å; L183-A187 VanDerWaalsContact O-CB 3.31Å; L183-A187 WeakPolarHBondContact O-CB 3.47Å; L183-A187 PolarHBondContact O-N 3.34Å
184K93.4Very high93.2Very high95 Ų9533.8 Ų33.841%0.41318%0.182SC..Hα-helixtrans-72.4-46.3-179.7-172.9175.1-177.1172.60110.6H129 D182 A187 I188H129-K184 HydrophobicContact CB-CB 4.12Å; D182-K184 VanDerWaalsContact C-N 3.26Å; D182-K184 PolarHBondContact O-N 3.26Å; D182-K184 WeakPolarHBondContact OD1-CB 3.32Å; D182-K184 PolarHBondContact OD1-N 3.47Å; K184-A187 PolarHBondContact O-N 3.24Å; K184-I188 WeakPolarHBondContact O-CG1 3.24Å; K184-I188 PolarHBondContact O-N 2.72Å
185S92.6Very high93.3Very high53 Ų5333.8 Ų33.837%0.37118%0.179SC..Hα-helixtrans-62.7-42.9175.2-176.40000111.9D182 A187 I188 S189D182-S185 VanDerWaalsContact CG-CB 3.41Å; D182-S185 PolarHBondContact O-N 3.12Å; D182-S185 PolarHBondContact OD1-N 2.98Å; S185-A187 PolarHBondContact O-N 3.21Å; S185-I188 PolarHBondContact O-N 3.15Å; S185-S189 WeakPolarHBondContact O-CB 3.28Å; S185-S189 PolarHBondContact O-N 2.9Å; S185-S189 PolarHBondContact O-OG 3.34Å
186T91.6Very high93.4Very high3 Ų333.2 Ų33.22%0.01817%0.174CC..Hα-helixtrans-64.2-39.1176.2-71.10000112.4F10 D182 I188 R190 C191 I192F10-T186 HydrophobicContact CD1-CG2 4.09Å; F10-T186 HydrophobicContact CD2-CG2 4.11Å; F10-T186 HydrophobicContact CE1-CG2 3.56Å; F10-T186 HydrophobicContact CE2-CG2 3.58Å; F10-T186 HydrophobicContact CG-CG2 4.35Å; F10-T186 HydrophobicContact CZ-CG2 3.28Å; D182-T186 WeakPolarHBondContact O-CB 3.23Å; D182-T186 PolarHBondContact O-N 3.26Å; D182-T186 PolarHBondContact O-OG1 2.96Å; T186-I188 VanDerWaalsContact C-N 3.26Å; T186-I188 PolarHBondContact O-N 3.09Å; T186-R190 WeakPolarHBondContact O-CA 3.4Å; T186-R190 PolarHBondContact O-N 3.05Å; T186-C191 WeakPolarHBondContact CA-O 3.47Å; T186-C191 WeakPolarHBondContact CB-O 3.34Å; T186-C191 WeakPolarHBondContact CG2-O 3.5Å; T186-C191 PolarHBondContact OG1-O 2.89Å; T186-I192 HydrophobicContact CG2-CB 4.43Å; T186-I192 HydrophobicContact CG2-CG1 3.68Å
187A89.2Confident93.5Very high6 Ų632 Ų325%0.0517%0.166CC..Hα-helixtrans-61.2-35.9177.700000112.9F10 N44 L183 K184 S185 R190F10-A187 HydrophobicContact CD1-CB 3.85Å; N44-A187 HydrophobicContact CB-CB 3.53Å; N44-A187 WeakPolarHBondContact O-CB 3.45Å; L183-A187 VanDerWaalsContact O-CB 3.31Å; L183-A187 WeakPolarHBondContact O-CB 3.47Å; L183-A187 PolarHBondContact O-N 3.34Å; K184-A187 PolarHBondContact O-N 3.24Å; S185-A187 PolarHBondContact O-N 3.21Å; A187-R190 PolarHBondContact O-NE 2.83Å
188I88.6Confident93.5Very high122 Ų12232.6 Ų32.663%0.62617%0.17SC*.Hα-helixtrans-78.1-51.4178.9-62.7165.2000110.9K184 S185 T186 R190K184-I188 WeakPolarHBondContact O-CG1 3.24Å; K184-I188 PolarHBondContact O-N 2.72Å; S185-I188 PolarHBondContact O-N 3.15Å; T186-I188 VanDerWaalsContact C-N 3.26Å; T186-I188 PolarHBondContact O-N 3.09Å; I188-R190 VanDerWaalsContact C-N 3.33Å; I188-R190 PolarHBondContact O-N 2.89Å
189S88.1Confident93.3Very high61 Ų6133.4 Ų33.443%0.42717%0.172SC..Hα-helixtrans-76.9-18.4-173.761.50000114S185 C191S185-S189 WeakPolarHBondContact O-CB 3.28Å; S185-S189 PolarHBondContact O-N 2.9Å; S185-S189 PolarHBondContact O-OG 3.34Å; S189-C191 PolarHBondContact O-N 3.25Å; S189-C191 VanDerWaalsContact O-N 3.16Å; S189-C191 PolarHBondContact OG-N 3.16Å; S189-C191 PolarHBondContact OG-O 3.47Å
190R85.5Confident93Very high120 Ų12035.4 Ų35.445%0.45318%0.181SC..SBendtrans5720.8-170.2-55.6-63.9-178.8167.5-11113.4F10 T186 A187 I188F10-R190 VanDerWaalsContact O-CZ 3.25Å; F10-R190 PolarHBondContact O-NH1 3.49Å; F10-R190 PolarHBondContact O-NH2 3.43Å; T186-R190 WeakPolarHBondContact O-CA 3.4Å; T186-R190 PolarHBondContact O-N 3.05Å; A187-R190 PolarHBondContact O-NE 2.83Å; I188-R190 VanDerWaalsContact C-N 3.33Å; I188-R190 PolarHBondContact O-N 2.89Å
191C88.7Confident92.5Very high39 Ų3937.6 Ų37.626%0.26419%0.19SC..  trans-119.8129.6176.8-173.60000109.3T186 S189 F225T186-C191 WeakPolarHBondContact CA-O 3.47Å; T186-C191 WeakPolarHBondContact CB-O 3.34Å; T186-C191 WeakPolarHBondContact CG2-O 3.5Å; T186-C191 PolarHBondContact OG1-O 2.89Å; S189-C191 PolarHBondContact O-N 3.25Å; S189-C191 VanDerWaalsContact O-N 3.16Å; S189-C191 PolarHBondContact OG-N 3.16Å; S189-C191 PolarHBondContact OG-O 3.47Å; C191-F225 PolarHBondContact SG-O 3Å
192I91.8Very high91.6Very high0 Ų042.1 Ų42.10%021%0.213CC..EExtended strand (participates in β ladder)trans-88.5114175.8-61.8168.7000107.6F10 F147 F154 I181 T186 L194 F225 V226 S227F10-I192 HydrophobicContact CE2-CD1 4.39Å; F10-I192 HydrophobicContact CE2-CG1 4.35Å; F147-I192 HydrophobicContact CD1-CD1 3.61Å; F147-I192 HydrophobicContact CE1-CD1 3.89Å; F147-I192 HydrophobicContact CE1-CG2 4.23Å; F154-I192 HydrophobicContact CB-CD1 4.07Å; I181-I192 HydrophobicContact CD1-CG2 3.96Å; I181-I192 HydrophobicContact CG1-CG2 4.31Å; T186-I192 HydrophobicContact CG2-CB 4.43Å; T186-I192 HydrophobicContact CG2-CG1 3.68Å; I192-L194 HydrophobicContact CG2-CD2 3.79Å; I192-L194 HydrophobicContact CG2-CG 4.3Å; I192-F225 HydrophobicContact CD1-CD2 4.43Å; I192-F225 HydrophobicContact CD1-CE2 4.25Å; I192-F225 PolarHBondContact N-O 3.32Å; I192-V226 HydrophobicContact CB-CG1 4.26Å; I192-V226 HydrophobicContact CB-CG2 4.27Å; I192-V226 HydrophobicContact CD1-CG2 4.37Å; I192-V226 HydrophobicContact CG2-CG1 4.22Å; I192-V226 WeakPolarHBondContact O-CA 3.39Å; I192-S227 PolarHBondContact O-N 3.48Å
193I93.7Very high90Very high67 Ų6742.3 Ų42.334%0.34422%0.219SC..EExtended strand (participates in β ladder)trans-102.6111.6175.3-58.4175000107.6V229I193-V229 HydrophobicContact CG2-CB 4.45Å; I193-V229 HydrophobicContact CG2-CG1 4.09Å; I193-V229 HydrophobicContact CG2-CG2 3.5Å
194L95.4Very high87.8Confident0 Ų054.8 Ų54.80%027%0.266CS..EExtended strand (participates in β ladder)trans-88.8102.4174.7-58.1-176.8000108.7F133 W145 F147 F179 I181 I192 L196 L222 V226 S227 V228 V229F133-L194 HydrophobicContact CZ-CD2 4.08Å; W145-L194 HydrophobicContact CE3-CD1 4.37Å; W145-L194 HydrophobicContact CH2-CD1 4.2Å; W145-L194 HydrophobicContact CZ3-CD1 3.9Å; F147-L194 HydrophobicContact CZ-CD1 4.28Å; F179-L194 HydrophobicContact CD1-CB 4.21Å; I181-L194 HydrophobicContact CD1-CD2 3.59Å; I181-L194 HydrophobicContact CG1-CD2 3.58Å; I192-L194 HydrophobicContact CG2-CD2 3.79Å; I192-L194 HydrophobicContact CG2-CG 4.3Å; L194-L196 PolarHBondContact O-N 3.34Å; L194-L222 HydrophobicContact CD1-CD1 4.04Å; L194-V226 HydrophobicContact CD1-CG1 3.84Å; L194-V226 HydrophobicContact CG-CG1 3.96Å; L194-S227 PolarHBondContact N-O 3.46Å; L194-V228 HydrophobicContact CB-CG1 4.4Å; L194-V228 HydrophobicContact CB-CG2 4.22Å; L194-V228 HydrophobicContact CD1-CG2 4.16Å; L194-V228 WeakPolarHBondContact O-CA 3.34Å; L194-V229 PolarHBondContact O-N 3.36Å
195Q96.4Very high85.6Confident33 Ų3357.4 Ų57.415%0.15428%0.279CS..EExtended strand (participates in β ladder)trans-82.4117.7174.3-174.9167.3-4.500110.3F179 R180 Y197 V229 N231F179-Q195 CarbonylContact C-O 3.17Å; F179-Q195 VanDerWaalsContact CA-O 3.3Å; F179-Q195 WeakPolarHBondContact CA-O 3.16Å; R180-Q195 HydrophobicContact CB-CB 4.38Å; R180-Q195 PolarHBondContact N-O 3.03Å; R180-Q195 PolarHBondContact O-N 2.85Å; Q195-Y197 HydrophobicContact CB-CE2 4.41Å; Q195-Y197 HydrophobicContact CG-CE2 3.86Å; Q195-Y197 PolarHBondContact NE2-OH 2.93Å; Q195-Y197 VanDerWaalsContact NE2-OH 3.15Å; Q195-V229 WeakPolarHBondContact CA-O 3.36Å; Q195-V229 HydrophobicContact CB-CG2 4.25Å; Q195-V229 HydrophobicContact CG-CG2 4.47Å; Q195-N231 HydrophobicContact CG-CB 3.93Å; Q195-N231 VanDerWaalsContact NE2-CB 3.27Å
196L95.9Very high83.1Confident3 Ų362.3 Ų62.32%0.01630%0.302CS..EExtended strand (participates in β ladder)trans-94.4130.1-177.4176.962.3000111.8F179 L194 P198 L215 I218 V228 V229 N231F179-L196 HydrophobicContact CD1-CB 4.44Å; F179-L196 HydrophobicContact CD1-CD1 4.14Å; F179-L196 HydrophobicContact CE1-CB 4.34Å; F179-L196 HydrophobicContact CE1-CD1 3.73Å; F179-L196 HydrophobicContact CE1-CG 4.48Å; F179-L196 HydrophobicContact CE2-CD1 4.29Å; F179-L196 HydrophobicContact CZ-CD1 3.81Å; L194-L196 PolarHBondContact O-N 3.34Å; L196-P198 HydrophobicContact CG-CB 4.41Å; L196-L215 HydrophobicContact CB-CD2 4.42Å; L196-L215 HydrophobicContact CD2-CD2 3.84Å; L196-L215 HydrophobicContact CD2-CG 4.48Å; L196-I218 HydrophobicContact CD2-CD1 4.25Å; L196-V228 HydrophobicContact CB-CG1 4.08Å; L196-V229 PolarHBondContact N-O 3.21Å; L196-N231 PolarHBondContact O-N 2.72Å; L196-N231 PolarHBondContact O-ND2 3.33Å; L196-N231 VanDerWaalsContact O-ND2 3.09Å
197Y96.4Very high80.8Confident0 Ų068.4 Ų68.40%033%0.333CS..EExtended strand (participates in β ladder)trans-112.998.4168.5-59.8-92.8000107.9E105 L109 W132 G177 L178 R180 Q195 N231 L235 L237E105-Y197 HydrophobicContact CB-CE1 4.5Å; E105-Y197 PolarHBondContact OE1-OH 2.94Å; E105-Y197 VanDerWaalsContact OE2-CE1 3.25Å; E105-Y197 WeakPolarHBondContact OE2-CE1 3.32Å; E105-Y197 PolarHBondContact OE2-OH 2.68Å; L109-Y197 HydrophobicContact CD1-CD1 3.55Å; L109-Y197 HydrophobicContact CD1-CE1 4.15Å; L109-Y197 HydrophobicContact CD1-CG 4.22Å; L109-Y197 HydrophobicContact CD2-CD1 4.08Å; L109-Y197 HydrophobicContact CD2-CG 3.89Å; L109-Y197 HydrophobicContact CG-CD1 4.37Å; W132-Y197 HydrophobicContact CE3-CE2 4.37Å; W132-Y197 HydrophobicContact CH2-CD2 4.4Å; W132-Y197 HydrophobicContact CH2-CE1 4.41Å; W132-Y197 AromaticContact CH2-CE2 3.7Å; W132-Y197 HydrophobicContact CH2-CE2 3.7Å; W132-Y197 AromaticContact CH2-CZ 3.68Å; W132-Y197 AromaticContact CZ3-CD2 3.7Å; W132-Y197 HydrophobicContact CZ3-CD2 3.7Å; W132-Y197 AromaticContact CZ3-CE2 3.4Å; W132-Y197 HydrophobicContact CZ3-CE2 3.4Å; W132-Y197 HydrophobicContact CZ3-CG 4.4Å; W132-Y197 AromaticContact CZ3-CZ 3.84Å; G177-Y197 CarbonylContact C-O 3.59Å; G177-Y197 WeakPolarHBondContact CA-O 3.47Å; L178-Y197 PolarHBondContact N-O 3.02Å; L178-Y197 PolarHBondContact O-N 3.39Å; R180-Y197 HydrophobicContact CB-CE2 3.95Å; Q195-Y197 HydrophobicContact CB-CE2 4.41Å; Q195-Y197 HydrophobicContact CG-CE2 3.86Å; Q195-Y197 PolarHBondContact NE2-OH 2.93Å; Q195-Y197 VanDerWaalsContact NE2-OH 3.15Å; Y197-N231 HydrophobicContact CD1-CB 3.85Å; Y197-N231 HydrophobicContact CE1-CB 3.53Å; Y197-L235 HydrophobicContact CD1-CB 4.07Å; Y197-L235 HydrophobicContact CE1-CB 4.35Å; Y197-L235 HydrophobicContact CE1-CD1 4.34Å; Y197-L237 WeakPolarHBondContact O-CD1 3.36Å
198P95.1Very high78.7Confident12 Ų1273.9 Ų73.98%0.07836%0.36CS..EExtended strand (participates in β ladder)trans-84.2159.3-166.233-36.5000113.2S176 L196 N211 Y236 L237S176-P198 VanDerWaalsContact O-CA 3.31Å; S176-P198 WeakPolarHBondContact O-CA 3.28Å; L196-P198 HydrophobicContact CG-CB 4.41Å; P198-N211 WeakPolarHBondContact CB-ND2 3.02Å; P198-N211 WeakPolarHBondContact CG-ND2 3.29Å; P198-Y236 CarbonylContact O-C 3.42Å; P198-Y236 VanDerWaalsContact O-CA 3.29Å; P198-Y236 WeakPolarHBondContact O-CA 3.34Å; P198-Y236 VanDerWaalsContact O-CB 3.26Å; P198-Y236 WeakPolarHBondContact O-CB 3.47Å; P198-L237 PolarHBondContact O-N 2.96Å
199W94.1Very high77.1Confident16 Ų1672.9 Ų72.96%0.06135%0.352CS..EExtended strand (participates in β ladder)trans-70.5136.9165.2-64.3110.4000111.7W119 F137 S176 L237 E238 K239W119-W199 HydrophobicContact CH2-CH2 4.33Å; W119-W199 AromaticContact CH2-CZ2 3.95Å; W119-W199 HydrophobicContact CH2-CZ2 3.95Å; W119-W199 AromaticContact CZ2-CH2 3.99Å; W119-W199 HydrophobicContact CZ2-CH2 3.99Å; W119-W199 AromaticContact CZ2-CZ2 3.95Å; W119-W199 HydrophobicContact CZ2-CZ2 3.95Å; F137-W199 HydrophobicContact CB-CD2 4.47Å; F137-W199 HydrophobicContact CB-CZ2 4.31Å; F137-W199 HydrophobicContact CD2-CB 4.23Å; F137-W199 HydrophobicContact CD2-CD2 4.06Å; F137-W199 AromaticContact CD2-CG 3.89Å; F137-W199 HydrophobicContact CD2-CG 3.89Å; F137-W199 HydrophobicContact CE2-CB 4.44Å; S176-W199 PolarHBondContact O-N 2.82Å; W199-L237 CarbonylContact C-O 3.48Å; W199-L237 WeakPolarHBondContact CA-O 3.31Å; W199-L237 HydrophobicContact CD2-CB 3.84Å; W199-L237 HydrophobicContact CE3-CB 3.25Å; W199-L237 HydrophobicContact CE3-CD2 4.34Å; W199-L237 HydrophobicContact CE3-CG 4.32Å; W199-L237 HydrophobicContact CH2-CB 4.07Å; W199-L237 HydrophobicContact CH2-CD2 3.61Å; W199-L237 HydrophobicContact CH2-CG 4.44Å; W199-L237 HydrophobicContact CZ2-CD2 3.98Å; W199-L237 HydrophobicContact CZ3-CB 3.39Å; W199-L237 HydrophobicContact CZ3-CD2 3.82Å; W199-L237 HydrophobicContact CZ3-CG 4.23Å; W199-E238 VanDerWaalsContact CE3-O 3.27Å; W199-E238 WeakPolarHBondContact CZ3-O 3.31Å; W199-K239 HydrophobicContact CB-CG 3.82Å
200K91.6Very high75.1Confident43 Ų4377.7 Ų77.719%0.18737%0.368CS..EExtended strand (participates in β ladder)trans-141.1149.2175.5-69-169.4177.91790112.4Y236 L237 K239K200-Y236 HydrophobicContact CB-CD2 3.85Å; K200-Y236 HydrophobicContact CB-CG 4.07Å; K200-Y236 HydrophobicContact CD-CD1 4.07Å; K200-Y236 HydrophobicContact CD-CD2 4.44Å; K200-Y236 HydrophobicContact CD-CG 3.86Å; K200-Y236 HydrophobicContact CG-CD2 4.48Å; K200-Y236 HydrophobicContact CG-CG 4.19Å; K200-L237 PolarHBondContact N-O 3.02Å; K200-K239 PolarHBondContact O-N 2.86Å
201Y87Confident73.4Confident65 Ų6573.9 Ų73.926%0.25536%0.357SS..  trans-77.3141.9165.8-65.6-67.7000109.7E209 K239 V241 P243Y201-E209 WeakPolarHBondContact CD2-OE2 3.46Å; Y201-K239 HydrophobicContact CD1-CB 3.79Å; Y201-K239 HydrophobicContact CD1-CD 3.61Å; Y201-K239 HydrophobicContact CD1-CG 4.27Å; Y201-K239 HydrophobicContact CD2-CD 3.61Å; Y201-K239 HydrophobicContact CE1-CB 3.83Å; Y201-K239 HydrophobicContact CE1-CD 3.45Å; Y201-K239 VanDerWaalsContact CE1-CD 3.45Å; Y201-K239 HydrophobicContact CE1-CG 4.26Å; Y201-K239 HydrophobicContact CE2-CD 3.48Å; Y201-K239 VanDerWaalsContact CE2-CD 3.48Å; Y201-K239 HydrophobicContact CG-CB 4.5Å; Y201-K239 HydrophobicContact CG-CD 3.68Å; Y201-V241 WeakPolarHBondContact CE1-O 3.35Å; Y201-P243 HydrophobicContact CD1-CG 3.66Å; Y201-P243 HydrophobicContact CD2-CG 4.04Å; Y201-P243 HydrophobicContact CE1-CB 4.22Å; Y201-P243 HydrophobicContact CE1-CG 3.67Å; Y201-P243 HydrophobicContact CE2-CB 4.18Å; Y201-P243 HydrophobicContact CE2-CG 4.03Å; Y201-P243 HydrophobicContact CG-CG 3.86Å
202I77.3Confident71.4Confident95 Ų9576.6 Ų76.649%0.48737%0.372SS..  trans-92.5102.9168.7-56.9-176.8000107.5Y236 E238I202-Y236 HydrophobicContact CD1-CE2 4.32Å; I202-Y236 HydrophobicContact CG1-CE2 4.05Å; I202-E238 HydrophobicContact CD1-CB 4.1Å; I202-E238 HydrophobicContact CD1-CG 3.78Å; I202-E238 WeakPolarHBondContact CD1-OE2 3.32Å; I202-E238 HydrophobicContact CG1-CB 4.45Å; I202-E238 HydrophobicContact CG1-CG 3.97Å
203S62.3Low69.6Low56 Ų5682.1 Ų82.139%0.39240%0.401SS..  trans-95.4141.2170.456.40000110.5E205S203-E205 VanDerWaalsContact CB-O 3.26Å; S203-E205 WeakPolarHBondContact CB-O 3.43Å; S203-E205 PolarHBondContact O-N 2.86Å; S203-E205 PolarHBondContact OG-O 2.81Å
204R50.1Low68.1Low262 Ų26280.9 Ų80.999%0.98940%0.399SS*.SBendtrans-66.2-24.3174.2-73.2-176.2178.4-176.7-0.1112.8
205E46.3Very low67.1Low150 Ų15082.8 Ų82.870%0.70141%0.409SS*.SBendtrans-100.3123.1171.2-66.4166.4-172.900106.5S203 I207S203-E205 VanDerWaalsContact CB-O 3.26Å; S203-E205 WeakPolarHBondContact CB-O 3.43Å; S203-E205 PolarHBondContact O-N 2.86Å; S203-E205 PolarHBondContact OG-O 2.81Å; E205-I207 PolarHBondContact O-N 2.93Å
206N40.7Very low65.8Low156 Ų15684.6 Ų84.683%0.83443%0.425SS*.  trans-62.648-173.4-71.7-46.6000115.3I208N206-I208 PolarHBondContact O-N 2.83Å
207I42Very low64.8Low131 Ų13190.7 Ų90.767%0.67245%0.453SS*.  trans-84.789.9172-54.8179.3000107.2E205 E209E205-I207 PolarHBondContact O-N 2.93Å; I207-E209 PolarHBondContact O-N 2.87Å
208I46.8Very low63.9Low121 Ų12191.5 Ų91.562%0.62146%0.458SS*.  trans-67.1114.8174.8-59.8170.2000107.6N206 E210N206-I208 PolarHBondContact O-N 2.83Å; I208-E210 PolarHBondContact O-N 2.91Å; I208-E210 VanDerWaalsContact O-N 3.07Å
209E53.4Low63.2Low100 Ų10093.3 Ų93.347%0.46747%0.471SS..  trans-55.3114.4160.6-97-177.9157.400107.7Y201 I207 N211 K239Y201-E209 WeakPolarHBondContact CD2-OE2 3.46Å; I207-E209 PolarHBondContact O-N 2.87Å; E209-N211 PolarHBondContact O-N 3.47Å; E209-N211 VanDerWaalsContact O-N 3.14Å; E209-K239 IonicContact OE1-NZ 3.88Å; E209-K239 IonicContact OE2-NZ 3.71Å; E209-K239 PolarHBondContact OE2-NZ 3.43Å
210E46.8Very low62.4Low163 Ų16396.4 Ų96.476%0.76250%0.499SS*.  trans-66113.4176.9-82-168.5161.700110.1I208 V212I208-E210 PolarHBondContact O-N 2.91Å; I208-E210 VanDerWaalsContact O-N 3.07Å; E210-V212 HydrophobicContact CB-CG2 4.32Å; E210-V212 PolarHBondContact O-N 3.14Å; E210-V212 VanDerWaalsContact O-N 3.13Å
211N49.8Very low61.8Low40 Ų40100 Ų10021%0.21452%0.521CS..THydrogen-bonded Turntrans-78.210.6-176.7-138.5-39000113.8P198 E209 N213 S214P198-N211 WeakPolarHBondContact CB-ND2 3.02Å; P198-N211 WeakPolarHBondContact CG-ND2 3.29Å; E209-N211 PolarHBondContact O-N 3.47Å; E209-N211 VanDerWaalsContact O-N 3.14Å; N211-N213 VanDerWaalsContact C-N 3.28Å; N211-N213 PolarHBondContact O-N 3.24Å; N211-S214 PolarHBondContact O-N 3.25Å
212V45.8Very low61.8Low96 Ų9697.8 Ų97.858%0.58251%0.513SS*.Hα-helixtrans-68.2-31-169.6-174.90000111.2E210 S216E210-V212 HydrophobicContact CB-CG2 4.32Å; E210-V212 PolarHBondContact O-N 3.14Å; E210-V212 VanDerWaalsContact O-N 3.13Å; V212-S216 PolarHBondContact O-OG 3.01Å
213N54Low62.3Low115 Ų11595 Ų9562%0.61550%0.501SS*.Hα-helixtrans-73.1-27-179.3-70.9-20.4000113.5N211 S216 Q217N211-N213 VanDerWaalsContact C-N 3.28Å; N211-N213 PolarHBondContact O-N 3.24Å; N213-S216 PolarHBondContact O-OG 3.08Å; N213-Q217 WeakPolarHBondContact O-CB 3.28Å; N213-Q217 WeakPolarHBondContact O-CG 3.18Å; N213-Q217 PolarHBondContact O-N 3.25Å
214S63.4Low63.4Low41 Ų4197.8 Ų97.829%0.28753%0.528SS..Hα-helixtrans-78.3-38.5-177.4-620000112.5N211 I218N211-S214 PolarHBondContact O-N 3.25Å; S214-I218 WeakPolarHBondContact O-CD1 3.48Å; S214-I218 WeakPolarHBondContact O-CG1 3.3Å; S214-I218 PolarHBondContact O-N 3.49Å; S214-I218 VanDerWaalsContact O-N 3.11Å
215L73.8Confident65.2Low41 Ų4187.5 Ų87.522%0.21549%0.49CS..Hα-helixtrans-66.6-42.2179.9-73.2164.2000112.5L196 I218 S219 V228 A230L196-L215 HydrophobicContact CB-CD2 4.42Å; L196-L215 HydrophobicContact CD2-CD2 3.84Å; L196-L215 HydrophobicContact CD2-CG 4.48Å; L215-I218 PolarHBondContact O-N 2.84Å; L215-S219 VanDerWaalsContact O-CB 3.32Å; L215-S219 WeakPolarHBondContact O-CB 3.43Å; L215-S219 PolarHBondContact O-N 3.09Å; L215-S219 PolarHBondContact O-OG 3.12Å; L215-V228 HydrophobicContact CD2-CB 4.32Å; L215-V228 HydrophobicContact CD2-CG1 3.66Å; L215-A230 HydrophobicContact CD1-CB 4.1Å
216S68.6Low67.3Low70 Ų7080.9 Ų80.949%0.4946%0.46SS..Hα-helixtrans-67.1-40.1179.755.50000112.1V212 N213 A220V212-S216 PolarHBondContact O-OG 3.01Å; N213-S216 PolarHBondContact O-OG 3.08Å; S216-A220 PolarHBondContact O-N 2.83Å; S216-A220 VanDerWaalsContact O-N 3.16Å
217Q74.7Confident69.8Low132 Ų13275.5 Ų75.562%0.61743%0.434SS*.Hα-helixtrans-63.6-45.9175.2-74.8174.71.800112.3N213 S219 A220N213-Q217 WeakPolarHBondContact O-CB 3.28Å; N213-Q217 WeakPolarHBondContact O-CG 3.18Å; N213-Q217 PolarHBondContact O-N 3.25Å; Q217-S219 VanDerWaalsContact C-N 3.35Å; Q217-A220 PolarHBondContact O-N 3.05Å
218I79.3Confident72.2Confident17 Ų1770 Ų709%0.08741%0.407CS..Hα-helixtrans-67.4-39.9-179.5-60.4166.6000110.6W145 P174 S176 F179 L196 S214 L215 A220 L222 V228W145-I218 HydrophobicContact CH2-CG2 3.93Å; W145-I218 HydrophobicContact CZ2-CG2 4.34Å; P174-I218 HydrophobicContact CB-CD1 4.23Å; P174-I218 HydrophobicContact CB-CG1 4.32Å; P174-I218 HydrophobicContact CG-CD1 4.13Å; P174-I218 HydrophobicContact CG-CG1 3.88Å; P174-I218 HydrophobicContact CG-CG2 4.15Å; S176-I218 WeakPolarHBondContact OG-CD1 3.35Å; F179-I218 HydrophobicContact CZ-CD1 4.31Å; L196-I218 HydrophobicContact CD2-CD1 4.25Å; S214-I218 WeakPolarHBondContact O-CD1 3.48Å; S214-I218 WeakPolarHBondContact O-CG1 3.3Å; S214-I218 PolarHBondContact O-N 3.49Å; S214-I218 VanDerWaalsContact O-N 3.11Å; L215-I218 PolarHBondContact O-N 2.84Å; I218-A220 VanDerWaalsContact C-N 3.3Å; I218-A220 PolarHBondContact O-N 2.87Å; I218-L222 HydrophobicContact CG2-CD1 4.11Å; I218-L222 WeakPolarHBondContact O-CG 3.47Å; I218-V228 HydrophobicContact CB-CG2 4.48Å; I218-V228 HydrophobicContact CG2-CG2 3.81Å
219S79.4Confident74.4Confident50 Ų5067.1 Ų67.135%0.3540%0.395SS..Hα-helixtrans-70-26.2-177.7-56.30000113.4L215 Q217 D221 L222L215-S219 VanDerWaalsContact O-CB 3.32Å; L215-S219 WeakPolarHBondContact O-CB 3.43Å; L215-S219 PolarHBondContact O-N 3.09Å; L215-S219 PolarHBondContact O-OG 3.12Å; Q217-S219 VanDerWaalsContact C-N 3.35Å; S219-D221 VanDerWaalsContact C-N 3.26Å; S219-D221 PolarHBondContact O-N 3.44Å; S219-L222 PolarHBondContact O-N 3.47Å
220A77.9Confident76.1Confident80 Ų8065.2 Ų65.266%0.66140%0.396SS*.Hα-helixtrans-63.5-31-176.900000113.5S216 Q217 I218S216-A220 PolarHBondContact O-N 2.83Å; S216-A220 VanDerWaalsContact O-N 3.16Å; Q217-A220 PolarHBondContact O-N 3.05Å; I218-A220 VanDerWaalsContact C-N 3.3Å; I218-A220 PolarHBondContact O-N 2.87Å
221D78.4Confident77.9Confident119 Ų11957.8 Ų57.864%0.63636%0.362SS*.THydrogen-bonded Turntrans-97.1-2.1-176.1-64.9-32.8000112.9Q171 S219Q171-D221 PolarHBondContact NE2-O 2.87Å; S219-D221 VanDerWaalsContact C-N 3.26Å; S219-D221 PolarHBondContact O-N 3.44Å
222L87.3Confident79.6Confident19 Ų1964.9 Ų64.910%0.09939%0.393CS..SBendtrans-91.1147.8-174.2-73.1173.6000112.8W145 F147 L194 I218 S219 V226 V228W145-L222 HydrophobicContact CZ2-CD2 3.82Å; F147-L222 HydrophobicContact CD2-CD2 4.23Å; F147-L222 HydrophobicContact CE2-CD2 3.48Å; F147-L222 VanDerWaalsContact CE2-CD2 3.48Å; F147-L222 HydrophobicContact CZ-CD2 4.11Å; L194-L222 HydrophobicContact CD1-CD1 4.04Å; I218-L222 HydrophobicContact CG2-CD1 4.11Å; I218-L222 WeakPolarHBondContact O-CG 3.47Å; S219-L222 PolarHBondContact O-N 3.47Å; L222-V226 HydrophobicContact CB-CB 4.25Å; L222-V226 HydrophobicContact CB-CG1 4.45Å; L222-V226 HydrophobicContact CD1-CG1 3.99Å; L222-V226 HydrophobicContact CD2-CG1 4.22Å; L222-V226 HydrophobicContact CG-CG1 4.46Å; L222-V228 HydrophobicContact CD1-CG2 3.35Å
223P86.9Confident81.6Confident37 Ų3763.5 Ų63.524%0.2439%0.392CS..  trans-60.2152173.3-20.831.8000112.2F147 F225 V226F147-P223 HydrophobicContact CB-CG 4.01Å; F147-P223 HydrophobicContact CD2-CG 4.31Å; F147-P223 HydrophobicContact CG-CG 4.4Å; P223-F225 HydrophobicContact CB-CD1 3.83Å; P223-F225 HydrophobicContact CB-CE1 3.37Å; P223-F225 HydrophobicContact CB-CE2 4.25Å; P223-F225 HydrophobicContact CB-CG 4.44Å; P223-F225 HydrophobicContact CB-CZ 3.61Å; P223-F225 HydrophobicContact CG-CE1 4.16Å; P223-F225 HydrophobicContact CG-CZ 3.93Å; P223-F225 PolarHBondContact O-N 2.8Å; P223-V226 HydrophobicContact CB-CG2 4.27Å; P223-V226 HydrophobicContact CG-CG2 4.26Å; P223-V226 WeakPolarHBondContact O-CB 3.48Å; P223-V226 PolarHBondContact O-N 2.91Å
224A86.9Confident83.2Confident114 Ų11465.9 Ų65.994%0.94240%0.397SS*.THydrogen-bonded Turntrans-58.3-21.6-176.200000115.6V226A224-V226 VanDerWaalsContact C-N 3.3Å
225F86.9Confident84.7Confident45 Ų4565.9 Ų65.920%0.19739%0.394CS..THydrogen-bonded Turntrans-88.34.417661.4-97.2000113.4F147 C191 I192 P223F147-F225 HydrophobicContact CB-CE2 3.93Å; F147-F225 HydrophobicContact CB-CZ 3.84Å; F147-F225 HydrophobicContact CD1-CE2 4.45Å; C191-F225 PolarHBondContact SG-O 3Å; I192-F225 HydrophobicContact CD1-CD2 4.43Å; I192-F225 HydrophobicContact CD1-CE2 4.25Å; I192-F225 PolarHBondContact N-O 3.32Å; P223-F225 HydrophobicContact CB-CD1 3.83Å; P223-F225 HydrophobicContact CB-CE1 3.37Å; P223-F225 HydrophobicContact CB-CE2 4.25Å; P223-F225 HydrophobicContact CB-CG 4.44Å; P223-F225 HydrophobicContact CB-CZ 3.61Å; P223-F225 HydrophobicContact CG-CE1 4.16Å; P223-F225 HydrophobicContact CG-CZ 3.93Å; P223-F225 PolarHBondContact O-N 2.8Å
226V90.9Very high85.6Confident12 Ų1268.6 Ų68.67%0.07340%0.402CS..EExtended strand (participates in β ladder)trans-117.4131.6176.6-170.50000108.1F147 I192 L194 L222 P223 A224F147-V226 HydrophobicContact CD1-CG2 3.65Å; F147-V226 HydrophobicContact CD2-CG2 4.33Å; F147-V226 HydrophobicContact CE1-CG1 4Å; F147-V226 HydrophobicContact CE1-CG2 3.84Å; F147-V226 HydrophobicContact CE2-CG2 4.5Å; F147-V226 HydrophobicContact CG-CG2 3.92Å; F147-V226 HydrophobicContact CZ-CG1 3.94Å; F147-V226 HydrophobicContact CZ-CG2 4.28Å; I192-V226 HydrophobicContact CB-CG1 4.26Å; I192-V226 HydrophobicContact CB-CG2 4.27Å; I192-V226 HydrophobicContact CD1-CG2 4.37Å; I192-V226 HydrophobicContact CG2-CG1 4.22Å; I192-V226 WeakPolarHBondContact O-CA 3.39Å; L194-V226 HydrophobicContact CD1-CG1 3.84Å; L194-V226 HydrophobicContact CG-CG1 3.96Å; L222-V226 HydrophobicContact CB-CB 4.25Å; L222-V226 HydrophobicContact CB-CG1 4.45Å; L222-V226 HydrophobicContact CD1-CG1 3.99Å; L222-V226 HydrophobicContact CD2-CG1 4.22Å; L222-V226 HydrophobicContact CG-CG1 4.46Å; P223-V226 HydrophobicContact CB-CG2 4.27Å; P223-V226 HydrophobicContact CG-CG2 4.26Å; P223-V226 WeakPolarHBondContact O-CB 3.48Å; P223-V226 PolarHBondContact O-N 2.91Å; A224-V226 VanDerWaalsContact C-N 3.3Å
227S91.8Very high86.9Confident42 Ų4265.3 Ų65.329%0.29438%0.379SS..EExtended strand (participates in β ladder)trans-129.3148.5175.459.10000110.4I192 L194I192-S227 PolarHBondContact O-N 3.48Å; L194-S227 PolarHBondContact N-O 3.46Å
228V93.3Very high87.9Confident16 Ų1663.7 Ų63.710%0.09737%0.371CS..EExtended strand (participates in β ladder)trans-110.6127.4173.4-167.80000108.6F179 L194 L196 L215 I218 L222F179-V228 HydrophobicContact CE1-CG1 4.46Å; L194-V228 HydrophobicContact CB-CG1 4.4Å; L194-V228 HydrophobicContact CB-CG2 4.22Å; L194-V228 HydrophobicContact CD1-CG2 4.16Å; L194-V228 WeakPolarHBondContact O-CA 3.34Å; L196-V228 HydrophobicContact CB-CG1 4.08Å; L215-V228 HydrophobicContact CD2-CB 4.32Å; L215-V228 HydrophobicContact CD2-CG1 3.66Å; I218-V228 HydrophobicContact CB-CG2 4.48Å; I218-V228 HydrophobicContact CG2-CG2 3.81Å; L222-V228 HydrophobicContact CD1-CG2 3.35Å
229V92.8Very high88.6Confident60 Ų6064.4 Ų64.436%0.36437%0.374SS..EExtended strand (participates in β ladder)trans-123.1142.9179.5-59.70000110I193 L194 Q195 L196I193-V229 HydrophobicContact CG2-CB 4.45Å; I193-V229 HydrophobicContact CG2-CG1 4.09Å; I193-V229 HydrophobicContact CG2-CG2 3.5Å; L194-V229 PolarHBondContact O-N 3.36Å; Q195-V229 WeakPolarHBondContact CA-O 3.36Å; Q195-V229 HydrophobicContact CB-CG2 4.25Å; Q195-V229 HydrophobicContact CG-CG2 4.47Å; L196-V229 PolarHBondContact N-O 3.21Å
230A88.5Confident89.4Confident60 Ų6063.3 Ų63.350%0.49637%0.365SS..EExtended strand (participates in β ladder)trans-68.1147.2167.700000109.6L215L215-A230 HydrophobicContact CD1-CB 4.1Å
231N86.4Confident90.2Very high7 Ų759.9 Ų59.94%0.03734%0.336CS..  trans-67.8135171.274.190.6000111.1Q195 L196 Y197 A233 K234 L235Q195-N231 HydrophobicContact CG-CB 3.93Å; Q195-N231 VanDerWaalsContact NE2-CB 3.27Å; L196-N231 PolarHBondContact O-N 2.72Å; L196-N231 PolarHBondContact O-ND2 3.33Å; L196-N231 VanDerWaalsContact O-ND2 3.09Å; Y197-N231 HydrophobicContact CD1-CB 3.85Å; Y197-N231 HydrophobicContact CE1-CB 3.53Å; N231-A233 VanDerWaalsContact C-N 3.28Å; N231-A233 PolarHBondContact O-N 2.62Å; N231-K234 PolarHBondContact O-N 3.38Å; N231-K234 VanDerWaalsContact O-N 3.15Å; N231-K234 WeakPolarHBondContact OD1-CA 3.29Å; N231-K234 PolarHBondContact OD1-N 2.85Å; N231-L235 PolarHBondContact ND2-O 2.88Å; N231-L235 PolarHBondContact OD1-N 2.68Å
232E84.5Confident91Very high189 Ų18957.3 Ų57.388%0.88332%0.324SS*.THydrogen-bonded Turntrans-63.7-34.2-175.2-62.7-177.7172.500112.8K234E232-K234 PolarHBondContact O-N 2.99Å
233A87.5Confident91.3Very high68 Ų6859.9 Ų59.956%0.56234%0.343SS*.THydrogen-bonded Turntrans-73.2-2.7179.400000113.9N231 L235N231-A233 VanDerWaalsContact C-N 3.28Å; N231-A233 PolarHBondContact O-N 2.62Å; A233-L235 HydrophobicContact CB-CD1 4.08Å; A233-L235 HydrophobicContact CB-CG 3.78Å; A233-L235 PolarHBondContact O-N 3.03Å; A233-L235 VanDerWaalsContact O-N 3.12Å
234K88.8Confident91.6Very high164 Ų16459.3 Ų59.371%0.71334%0.337SS*.  trans53.426.7-177.3-58.5-179.4-179.5177.70114.3N231 E232 Y236N231-K234 PolarHBondContact O-N 3.38Å; N231-K234 VanDerWaalsContact O-N 3.15Å; N231-K234 WeakPolarHBondContact OD1-CA 3.29Å; N231-K234 PolarHBondContact OD1-N 2.85Å; E232-K234 PolarHBondContact O-N 2.99Å; K234-Y236 WeakPolarHBondContact O-CD1 3.41Å
235L93.3Very high92.1Very high41 Ų4155.4 Ų55.422%0.21530%0.301CS..  trans-65.1151.1172.4-58.6175.7000110.7E105 L109 Y197 N231 A233E105-L235 HydrophobicContact CB-CD1 3.8Å; L109-L235 HydrophobicContact CD1-CB 3.45Å; L109-L235 VanDerWaalsContact CD1-CB 3.45Å; L109-L235 HydrophobicContact CD1-CD1 4.04Å; L109-L235 HydrophobicContact CD1-CG 4.32Å; Y197-L235 HydrophobicContact CD1-CB 4.07Å; Y197-L235 HydrophobicContact CE1-CB 4.35Å; Y197-L235 HydrophobicContact CE1-CD1 4.34Å; N231-L235 PolarHBondContact ND2-O 2.88Å; N231-L235 PolarHBondContact OD1-N 2.68Å; A233-L235 HydrophobicContact CB-CD1 4.08Å; A233-L235 HydrophobicContact CB-CG 3.78Å; A233-L235 PolarHBondContact O-N 3.03Å; A233-L235 VanDerWaalsContact O-N 3.12Å
236Y94.3Very high92.4Very high99 Ų9956.9 Ų56.939%0.38831%0.309SS..  trans-150.1165.3-175.256.4-91.4000110.3P198 K200 I202 K234P198-Y236 CarbonylContact O-C 3.42Å; P198-Y236 VanDerWaalsContact O-CA 3.29Å; P198-Y236 WeakPolarHBondContact O-CA 3.34Å; P198-Y236 VanDerWaalsContact O-CB 3.26Å; P198-Y236 WeakPolarHBondContact O-CB 3.47Å; K200-Y236 HydrophobicContact CB-CD2 3.85Å; K200-Y236 HydrophobicContact CB-CG 4.07Å; K200-Y236 HydrophobicContact CD-CD1 4.07Å; K200-Y236 HydrophobicContact CD-CD2 4.44Å; K200-Y236 HydrophobicContact CD-CG 3.86Å; K200-Y236 HydrophobicContact CG-CD2 4.48Å; K200-Y236 HydrophobicContact CG-CG 4.19Å; I202-Y236 HydrophobicContact CD1-CE2 4.32Å; I202-Y236 HydrophobicContact CG1-CE2 4.05Å; K234-Y236 WeakPolarHBondContact O-CD1 3.41Å
237L95.6Very high92.5Very high0 Ų061.7 Ų61.70%033%0.332CS..EExtended strand (participates in β ladder)trans-96.2142.1165.4-62.197.3000109.7L109 F112 S113 L178 Y197 P198 W199 K200L109-L237 HydrophobicContact CB-CG 4.49Å; L109-L237 HydrophobicContact CD2-CD1 3.66Å; L109-L237 HydrophobicContact CD2-CD2 4.44Å; L109-L237 HydrophobicContact CD2-CG 3.8Å; F112-L237 HydrophobicContact CB-CD2 3.67Å; S113-L237 VanDerWaalsContact OG-CA 3.28Å; S113-L237 WeakPolarHBondContact OG-CA 3.15Å; S113-L237 WeakPolarHBondContact OG-CB 3.46Å; L178-L237 HydrophobicContact CB-CD1 4.28Å; L178-L237 HydrophobicContact CD1-CD1 4.43Å; L178-L237 HydrophobicContact CD1-CD2 3.94Å; L178-L237 HydrophobicContact CD2-CD2 4.38Å; L178-L237 HydrophobicContact CG-CD1 3.8Å; L178-L237 HydrophobicContact CG-CD2 3.8Å; L178-L237 HydrophobicContact CG-CG 4.38Å; Y197-L237 WeakPolarHBondContact O-CD1 3.36Å; P198-L237 PolarHBondContact O-N 2.96Å; W199-L237 CarbonylContact C-O 3.48Å; W199-L237 WeakPolarHBondContact CA-O 3.31Å; W199-L237 HydrophobicContact CD2-CB 3.84Å; W199-L237 HydrophobicContact CE3-CB 3.25Å; W199-L237 HydrophobicContact CE3-CD2 4.34Å; W199-L237 HydrophobicContact CE3-CG 4.32Å; W199-L237 HydrophobicContact CH2-CB 4.07Å; W199-L237 HydrophobicContact CH2-CD2 3.61Å; W199-L237 HydrophobicContact CH2-CG 4.44Å; W199-L237 HydrophobicContact CZ2-CD2 3.98Å; W199-L237 HydrophobicContact CZ3-CB 3.39Å; W199-L237 HydrophobicContact CZ3-CD2 3.82Å; W199-L237 HydrophobicContact CZ3-CG 4.23Å; K200-L237 PolarHBondContact N-O 3.02Å
238E95Very high92.5Very high98 Ų9863.5 Ų63.546%0.45834%0.338SS..EExtended strand (participates in β ladder)trans-74.5127.6173.4-179.4170.8-171.900110.1S113 W199 I202S113-E238 PolarHBondContact OG-N 2.84Å; W199-E238 VanDerWaalsContact CE3-O 3.27Å; W199-E238 WeakPolarHBondContact CZ3-O 3.31Å; I202-E238 HydrophobicContact CD1-CB 4.1Å; I202-E238 HydrophobicContact CD1-CG 3.78Å; I202-E238 WeakPolarHBondContact CD1-OE2 3.32Å; I202-E238 HydrophobicContact CG1-CB 4.45Å; I202-E238 HydrophobicContact CG1-CG 3.97Å
239K94.8Very high92.3Very high33 Ų3364.7 Ų64.714%0.14335%0.346CS..PPolyproline II helixtrans-61.6127.5174.5-75.8177.5-1791730109F137 W199 K200 Y201 E209 V241F137-K239 HydrophobicContact CD2-CG 4.13Å; F137-K239 HydrophobicContact CE2-CB 4.27Å; F137-K239 HydrophobicContact CE2-CD 3.86Å; F137-K239 HydrophobicContact CE2-CG 3.63Å; F137-K239 HydrophobicContact CZ-CD 4.28Å; F137-K239 HydrophobicContact CZ-CG 4.32Å; W199-K239 HydrophobicContact CB-CG 3.82Å; K200-K239 PolarHBondContact O-N 2.86Å; Y201-K239 HydrophobicContact CD1-CB 3.79Å; Y201-K239 HydrophobicContact CD1-CD 3.61Å; Y201-K239 HydrophobicContact CD1-CG 4.27Å; Y201-K239 HydrophobicContact CD2-CD 3.61Å; Y201-K239 HydrophobicContact CE1-CB 3.83Å; Y201-K239 HydrophobicContact CE1-CD 3.45Å; Y201-K239 VanDerWaalsContact CE1-CD 3.45Å; Y201-K239 HydrophobicContact CE1-CG 4.26Å; Y201-K239 HydrophobicContact CE2-CD 3.48Å; Y201-K239 VanDerWaalsContact CE2-CD 3.48Å; Y201-K239 HydrophobicContact CG-CB 4.5Å; Y201-K239 HydrophobicContact CG-CD 3.68Å; E209-K239 IonicContact OE1-NZ 3.88Å; E209-K239 IonicContact OE2-NZ 3.71Å; E209-K239 PolarHBondContact OE2-NZ 3.43Å; K239-V241 PolarHBondContact O-N 3.34Å
240P95.3Very high91.6Very high27 Ų2771.2 Ų71.218%0.17537%0.373CS..SBendtrans-79.511.6-174.134.6-38.4000113.4F137 E555F137-P240 HydrophobicContact CB-CG 3.7Å; F137-P240 HydrophobicContact CD1-CG 4.2Å; F137-P240 HydrophobicContact CG-CG 4Å; P240-E555 HydrophobicContact CB-CG 3.93Å; P240-E555 HydrophobicContact CG-CG 4.1Å
241V95.6Very high90.9Very high8 Ų872 Ų725%0.04838%0.379CS..SBendtrans-136.6157.7-179.1-59.50000111F137 F138 Y201 K239 E555 V558 S559F137-V241 HydrophobicContact CD1-CG2 4.23Å; F137-V241 HydrophobicContact CE1-CG2 3.53Å; F137-V241 HydrophobicContact CZ-CG2 4.03Å; F138-V241 HydrophobicContact CE2-CG1 4.5Å; F138-V241 HydrophobicContact CZ-CG1 3.8Å; Y201-V241 WeakPolarHBondContact CE1-O 3.35Å; K239-V241 PolarHBondContact O-N 3.34Å; V241-E555 HydrophobicContact CG1-CB 4.33Å; V241-V558 HydrophobicContact CB-CG1 4.25Å; V241-V558 HydrophobicContact CG1-CB 4.03Å; V241-V558 HydrophobicContact CG1-CG1 3.91Å; V241-V558 HydrophobicContact CG2-CG1 4.42Å; V241-S559 VanDerWaalsContact CA-OG 3.27Å; V241-S559 WeakPolarHBondContact CA-OG 3.4Å
242V94.1Very high90Very high64 Ų6476.1 Ų76.139%0.38841%0.414SS..PPolyproline II helixtrans-74.8152.6171.3-56.30000111.3S559 N562V242-S559 VanDerWaalsContact CG2-O 3.27Å; V242-S559 WeakPolarHBondContact CG2-O 3.24Å; V242-S559 PolarHBondContact N-OG 3.02Å; V242-N562 HydrophobicContact CG2-CB 3.8Å; V242-N562 WeakPolarHBondContact O-CB 3.09Å; V242-N562 PolarHBondContact O-ND2 3.11Å
243P94.2Very high89.1Confident74 Ų7471.2 Ų71.248%0.48139%0.393SS..PPolyproline II helixtrans-56.3146.8173.6-22.631.5000112.7Y201 N245Y201-P243 HydrophobicContact CD1-CG 3.66Å; Y201-P243 HydrophobicContact CD2-CG 4.04Å; Y201-P243 HydrophobicContact CE1-CB 4.22Å; Y201-P243 HydrophobicContact CE1-CG 3.67Å; Y201-P243 HydrophobicContact CE2-CB 4.18Å; Y201-P243 HydrophobicContact CE2-CG 4.03Å; Y201-P243 HydrophobicContact CG-CG 3.86Å; P243-N245 PolarHBondContact O-N 3.2Å
244L94.3Very high87.4Confident25 Ų2575.6 Ų75.613%0.13140%0.402CS..PPolyproline II helixtrans-59.2126.7173.1178.864.3000109.7M246 I522 M523 L526L244-M246 HydrophobicContact CD2-SD 3.67Å; L244-M246 HydrophobicContact CG-SD 3.94Å; L244-M246 WeakPolarHBondContact O-CG 3.37Å; L244-M246 PolarHBondContact O-N 2.94Å; L244-M246 VanDerWaalsContact O-N 3.07Å; L244-I522 HydrophobicContact CD1-CG2 4.47Å; L244-I522 HydrophobicContact CD2-CG2 3.93Å; L244-M523 HydrophobicContact CD2-CB 3.97Å; L244-L526 HydrophobicContact CD2-CD1 4.44Å
245N95.7Very high85.7Confident32 Ų3271.3 Ų71.317%0.17139%0.39CS..  trans-67.5106.8174.7-176-16.9000110P243 M247 N562 S563P243-N245 PolarHBondContact O-N 3.2Å; N245-M247 WeakPolarHBondContact OD1-CB 3.41Å; N245-M247 WeakPolarHBondContact OD1-CG 3.32Å; N245-M247 PolarHBondContact OD1-N 2.95Å; N245-N562 WeakPolarHBondContact CB-O 3.38Å; N245-N562 PolarHBondContact N-O 3.3Å; N245-S563 PolarHBondContact ND2-O 2.98Å
246M93.7Very high83.6Confident75 Ų7576.7 Ų76.737%0.36941%0.414SS..  trans-96.88.9179-59.7-63.8-81.600112.7L244 N519 M523L244-M246 HydrophobicContact CD2-SD 3.67Å; L244-M246 HydrophobicContact CG-SD 3.94Å; L244-M246 WeakPolarHBondContact O-CG 3.37Å; L244-M246 PolarHBondContact O-N 2.94Å; L244-M246 VanDerWaalsContact O-N 3.07Å; M246-N519 HydrophobicContact CE-CB 3.66Å; M246-N519 PolarHBondContact O-ND2 2.78Å; M246-N519 HydrophobicContact SD-CB 3.8Å; M246-M523 HydrophobicContact CE-CB 4.41Å; M246-M523 HydrophobicContact CE-SD 4.09Å
247M93.8Very high81.5Confident114 Ų11472.7 Ų72.756%0.56240%0.4SS*.  trans-57.5149.1179.6-67.9179.464.900110.6N245 W567N245-M247 WeakPolarHBondContact OD1-CB 3.41Å; N245-M247 WeakPolarHBondContact OD1-CG 3.32Å; N245-M247 PolarHBondContact OD1-N 2.95Å; M247-W567 HydrophobicContact CB-CH2 4.42Å; M247-W567 WeakPolarHBondContact O-CZ3 3.46Å
248L91.4Very high79.2Confident79 Ų7977 Ų7741%0.41443%0.43SS..  trans-112.5149.1171.2-63.2178.2000108.3Q250 L515 E516L248-Q250 PolarHBondContact O-N 3.16Å; L248-L515 HydrophobicContact CD2-CB 3.9Å; L248-E516 HydrophobicContact CD1-CB 4.17Å; L248-E516 HydrophobicContact CD1-CG 4.41Å; L248-E516 HydrophobicContact CD2-CB 4.28Å
249P88.1Confident76.9Confident41 Ų4179.4 Ų79.427%0.26645%0.446SS..  trans-66.2136.7-179.230.2-34.6000109.8A251 L253 L515 W567P249-A251 VanDerWaalsContact C-N 3.3Å; P249-A251 WeakPolarHBondContact CB-O 3.18Å; P249-A251 PolarHBondContact O-N 3.33Å; P249-L253 HydrophobicContact CB-CD1 4.32Å; P249-L253 HydrophobicContact CB-CD2 4.22Å; P249-L253 HydrophobicContact CB-CG 3.9Å; P249-L253 HydrophobicContact CG-CD1 3.93Å; P249-L253 HydrophobicContact CG-CG 3.92Å; P249-L515 HydrophobicContact CG-CD1 3.9Å; P249-W567 HydrophobicContact CB-CH2 4.27Å; P249-W567 HydrophobicContact CB-CZ2 4.43Å; P249-W567 HydrophobicContact CB-CZ3 4.41Å; P249-W567 VanDerWaalsContact CD-CZ3 3.47Å; P249-W567 HydrophobicContact CG-CZ3 4.37Å
250Q78Confident75Confident198 Ų19879.5 Ų79.593%0.92545%0.448SS*.SBendtrans-71.7-25-177.4-70179.8-4.600113L248L248-Q250 PolarHBondContact O-N 3.16Å
251A74Confident72.9Confident75 Ų7582 Ų8262%0.6247%0.466SS*.SBendtrans-120.9162171.300000109.7P249 L253P249-A251 VanDerWaalsContact C-N 3.3Å; P249-A251 WeakPolarHBondContact CB-O 3.18Å; P249-A251 PolarHBondContact O-N 3.33Å; A251-L253 PolarHBondContact O-N 3.41Å; A251-L253 VanDerWaalsContact O-N 3.13Å
252A67.4Low70.8Confident95 Ų9589 Ų8979%0.78550%0.503SS*.  trans-57.5121.9170.500000108.3E254A252-E254 PolarHBondContact O-N 3.42Å
253L65.5Low69.1Low85 Ų8589.4 Ų89.445%0.44551%0.505SS..  trans-54.9116.6175-75.3160000107.7P249 A251 T255 L515 W567P249-L253 HydrophobicContact CB-CD1 4.32Å; P249-L253 HydrophobicContact CB-CD2 4.22Å; P249-L253 HydrophobicContact CB-CG 3.9Å; P249-L253 HydrophobicContact CG-CD1 3.93Å; P249-L253 HydrophobicContact CG-CG 3.92Å; A251-L253 PolarHBondContact O-N 3.41Å; A251-L253 VanDerWaalsContact O-N 3.13Å; L253-T255 PolarHBondContact O-N 2.98Å; L253-L515 HydrophobicContact CD1-CD1 3.88Å; L253-W567 HydrophobicContact CD1-CB 3.76Å; L253-W567 HydrophobicContact CD1-CD2 4.21Å; L253-W567 HydrophobicContact CD1-CG 3.87Å; L253-W567 HydrophobicContact CD2-CG 4.2Å
254E53.2Low67.7Low160 Ų16090.3 Ų90.375%0.74851%0.511SS*.  trans-59.1111171.2-71.1-174.1-179.400107.1A252 H256A252-E254 PolarHBondContact O-N 3.42Å; E254-H256 VanDerWaalsContact C-N 3.29Å; E254-H256 PolarHBondContact O-N 3.26Å
255T52.7Low66.4Low74 Ų7491.7 Ų91.745%0.45452%0.522SS..  trans-68.794.7172.417.20000106.8L253 C257 S258L253-T255 PolarHBondContact O-N 2.98Å; T255-C257 PolarHBondContact O-N 2.81Å; T255-S258 PolarHBondContact O-N 2.82Å
256H49.3Very low65.6Low155 Ų15592 Ų9272%0.71853%0.525SS*.THydrogen-bonded Turntrans-56.75.6169.1-73.6-66.9000113.7E254E254-H256 VanDerWaalsContact C-N 3.29Å; E254-H256 PolarHBondContact O-N 3.26Å
257C50.8Low64.8Low15 Ų1593.9 Ų93.910%0.10153%0.528CS..THydrogen-bonded Turntrans-14432.1-170.2-58.70000113.1T255 N259 I260 L574T255-C257 PolarHBondContact O-N 2.81Å; C257-N259 PolarHBondContact O-N 2.74Å; C257-N259 VanDerWaalsContact O-N 3.08Å; C257-I260 HydrophobicContact CB-CB 4.16Å; C257-I260 HydrophobicContact CB-CD1 3.56Å; C257-I260 HydrophobicContact CB-CG1 3.82Å; C257-I260 PolarHBondContact O-N 2.83Å; C257-I260 VanDerWaalsContact O-N 3.12Å; C257-I260 VanDerWaalsContact SG-CD1 3.51Å; C257-L574 HydrophobicContact CB-CD2 3.96Å
258S45.7Very low64.2Low89 Ų8994.3 Ų94.362%0.62253%0.529SS*.THydrogen-bonded Turntrans-59.9-16.1176.336.10000114T255T255-S258 PolarHBondContact O-N 2.82Å
259N48.1Very low63.7Low150 Ų15091.1 Ų91.180%0.80251%0.512SS*.THydrogen-bonded Turntrans-98.22176.3-72.1-19.2000115.3C257C257-N259 PolarHBondContact O-N 2.74Å; C257-N259 VanDerWaalsContact O-N 3.08Å
260I54.4Low63.6Low34 Ų3489.2 Ų89.217%0.17450%0.5CS..  trans-96.8-8.2-171.8-52.4-172.8000113.2C257 N262 V263 T269C257-I260 HydrophobicContact CB-CB 4.16Å; C257-I260 HydrophobicContact CB-CD1 3.56Å; C257-I260 HydrophobicContact CB-CG1 3.82Å; C257-I260 PolarHBondContact O-N 2.83Å; C257-I260 VanDerWaalsContact O-N 3.12Å; C257-I260 VanDerWaalsContact SG-CD1 3.51Å; I260-N262 PolarHBondContact O-N 2.91Å; I260-V263 PolarHBondContact O-N 3.02Å; I260-T269 HydrophobicContact CD1-CG2 4.3Å; I260-T269 HydrophobicContact CG2-CG2 3.95Å
261S50.9Low64Low81 Ų8183.8 Ų83.857%0.56648%0.475SS*.THydrogen-bonded Turntrans-63.8-17.7-170.672.20000115.4
262N52.6Low64.6Low154 Ų15483.8 Ų83.882%0.82447%0.467SS*.THydrogen-bonded Turntrans-109.82.1-177.3-71.7-17.4000114.9I260I260-N262 PolarHBondContact O-N 2.91Å
263V57.9Low65.5Low72 Ų7280.4 Ų80.444%0.43644%0.435SS..SBendtrans-98.3138.2-178.8-175.20000109.5I260I260-V263 PolarHBondContact O-N 3.02Å
264P64Low66.6Low93 Ų9377 Ų7760%0.60442%0.417SS*.  trans-54.5149.7173.719.9-31.2000111.2T266P264-T266 WeakPolarHBondContact O-CG2 3.39Å; P264-T266 PolarHBondContact O-N 2.73Å
265P67.5Low68.3Low54 Ų5474.9 Ų74.935%0.35142%0.415SS..  trans-64107.8-178.528-35.3000109.9I578P265-I578 HydrophobicContact CB-CD1 3.64Å; P265-I578 HydrophobicContact CB-CG1 3.43Å; P265-I578 VanDerWaalsContact CB-CG1 3.43Å
266T78.3Confident70.2Confident40 Ų4074.5 Ų74.525%0.24541%0.41CS..  trans-113.4161.7-179.478.30000112.1P264 E268 T269P264-T266 WeakPolarHBondContact O-CG2 3.39Å; P264-T266 PolarHBondContact O-N 2.73Å; T266-E268 WeakPolarHBondContact CB-OE2 3.41Å; T266-E268 PolarHBondContact O-N 2.89Å; T266-E268 PolarHBondContact OG1-N 3.11Å; T266-E268 PolarHBondContact OG1-OE2 3.41Å; T266-T269 WeakPolarHBondContact O-CB 3.11Å; T266-T269 PolarHBondContact O-N 3.29Å
267R77.6Confident72.3Confident114 Ų11472 Ų7243%0.4341%0.405SS..Hα-helixtrans-61.1-35.5176.6-176.7-179.8178.2172.92.8111.4T269 L270 Q271 L598R267-T269 PolarHBondContact O-N 3.27Å; R267-L270 PolarHBondContact O-N 2.89Å; R267-L270 VanDerWaalsContact O-N 3.08Å; R267-Q271 PolarHBondContact O-N 2.84Å; R267-L598 HydrophobicContact CB-CD1 4.44Å
268E80.3Confident74.3Confident123 Ų12375.8 Ų75.858%0.57542%0.421SS*.Hα-helixtrans-60-35.3179.4-60.569.6-146.100110.9T266 L270 Q271 V272T266-E268 WeakPolarHBondContact CB-OE2 3.41Å; T266-E268 PolarHBondContact O-N 2.89Å; T266-E268 PolarHBondContact OG1-N 3.11Å; T266-E268 PolarHBondContact OG1-OE2 3.41Å; E268-L270 VanDerWaalsContact C-N 3.34Å; E268-L270 PolarHBondContact O-N 3.28Å; E268-Q271 WeakPolarHBondContact O-CB 3.49Å; E268-Q271 PolarHBondContact O-N 3.11Å; E268-V272 WeakPolarHBondContact O-CG2 3.34Å; E268-V272 PolarHBondContact O-N 3.36Å; E268-V272 VanDerWaalsContact O-N 3.12Å
269T80.9Confident76.6Confident11 Ų1173.7 Ų73.77%0.06740%0.403CS..Hα-helixtrans-60.6-42.8175.7-56.60000111.7I260 T266 R267 F273 I578I260-T269 HydrophobicContact CD1-CG2 4.3Å; I260-T269 HydrophobicContact CG2-CG2 3.95Å; T266-T269 WeakPolarHBondContact O-CB 3.11Å; T266-T269 PolarHBondContact O-N 3.29Å; R267-T269 PolarHBondContact O-N 3.27Å; T269-F273 VanDerWaalsContact O-CD2 3.23Å; T269-F273 WeakPolarHBondContact O-CD2 3.34Å; T269-I578 HydrophobicContact CG2-CG2 4.14Å
270L86.6Confident78.9Confident1 Ų171.5 Ų71.51%0.00539%0.386CS..Hα-helixtrans-71.6-36.2175.7-67.3179.3000111.4R267 E268 V272 F273 L274 I578 L582 R585 L586 V589 A597 L598R267-L270 PolarHBondContact O-N 2.89Å; R267-L270 VanDerWaalsContact O-N 3.08Å; E268-L270 VanDerWaalsContact C-N 3.34Å; E268-L270 PolarHBondContact O-N 3.28Å; L270-V272 VanDerWaalsContact C-N 3.26Å; L270-V272 PolarHBondContact O-N 2.84Å; L270-F273 PolarHBondContact O-N 2.56Å; L270-F273 VanDerWaalsContact O-N 3.15Å; L270-L274 PolarHBondContact O-N 3.03Å; L270-I578 HydrophobicContact CD2-CD1 4.28Å; L270-I578 HydrophobicContact CD2-CG2 4.01Å; L270-I578 HydrophobicContact CG-CD1 4.16Å; L270-L582 HydrophobicContact CD2-CD1 3.81Å; L270-R585 HydrophobicContact CD1-CB 4.18Å; L270-R585 HydrophobicContact CD2-CB 4.22Å; L270-L586 HydrophobicContact CB-CD2 3.96Å; L270-L586 HydrophobicContact CD2-CD2 3.9Å; L270-L586 HydrophobicContact CG-CD2 4.49Å; L270-L586 WeakPolarHBondContact O-CD2 3.21Å; L270-V589 HydrophobicContact CB-CG2 4.4Å; L270-V589 HydrophobicContact CD1-CG2 3.85Å; L270-A597 HydrophobicContact CD1-CB 4.27Å; L270-L598 HydrophobicContact CD1-CD2 3.65Å; L270-L598 HydrophobicContact CG-CD2 4.21Å
271Q85.6Confident80.9Confident84 Ų8475 Ų7539%0.39340%0.401SS..Hα-helixtrans-62.8-31.5-178.7-160.567.445.400112.8R267 E268 F273 L274R267-Q271 PolarHBondContact O-N 2.84Å; E268-Q271 WeakPolarHBondContact O-CB 3.49Å; E268-Q271 PolarHBondContact O-N 3.11Å; Q271-F273 VanDerWaalsContact C-N 3.35Å; Q271-F273 PolarHBondContact O-N 2.92Å; Q271-L274 WeakPolarHBondContact O-CB 3.48Å; Q271-L274 PolarHBondContact O-N 2.87Å
272V86.9Confident83.2Confident76 Ų7671.5 Ų71.546%0.46138%0.377SS..Hα-helixtrans-59.9-44.1174.7172.40000111.2E268 L270 L274 T275E268-V272 WeakPolarHBondContact O-CG2 3.34Å; E268-V272 PolarHBondContact O-N 3.36Å; E268-V272 VanDerWaalsContact O-N 3.12Å; L270-V272 VanDerWaalsContact C-N 3.26Å; L270-V272 PolarHBondContact O-N 2.84Å; V272-L274 PolarHBondContact O-N 3.09Å; V272-T275 WeakPolarHBondContact O-CB 3.2Å; V272-T275 PolarHBondContact O-N 3.17Å; V272-T275 VanDerWaalsContact O-N 3.08Å; V272-T275 PolarHBondContact O-OG1 3.23Å
273F86.9Confident85.4Confident24 Ų2464.2 Ų64.211%0.10534%0.338CS..Hα-helixtrans-63.2-29.6177.4-68.1-81.8000112.6T269 L270 Q271 T275 D276 I279 L574 L582 L586T269-F273 VanDerWaalsContact O-CD2 3.23Å; T269-F273 WeakPolarHBondContact O-CD2 3.34Å; L270-F273 PolarHBondContact O-N 2.56Å; L270-F273 VanDerWaalsContact O-N 3.15Å; Q271-F273 VanDerWaalsContact C-N 3.35Å; Q271-F273 PolarHBondContact O-N 2.92Å; F273-T275 PolarHBondContact O-N 3.05Å; F273-D276 PolarHBondContact O-N 3.23Å; F273-I279 HydrophobicContact CB-CD1 4.38Å; F273-I279 HydrophobicContact CB-CG2 4.43Å; F273-I279 HydrophobicContact CD1-CD1 3.89Å; F273-L574 HydrophobicContact CE2-CD1 3.97Å; F273-L574 HydrophobicContact CZ-CD1 3.73Å; F273-L582 HydrophobicContact CD2-CD1 4.5Å; F273-L582 HydrophobicContact CE1-CD2 4.26Å; F273-L582 HydrophobicContact CZ-CD2 4.4Å; F273-L586 HydrophobicContact CB-CD1 3.84Å; F273-L586 HydrophobicContact CB-CD2 3.74Å; F273-L586 HydrophobicContact CB-CG 4.47Å; F273-L586 HydrophobicContact CG-CD1 4.36Å; F273-L586 HydrophobicContact CG-CD2 4.44Å
274L88.3Confident87.3Confident14 Ų1464.9 Ų64.97%0.07334%0.336CS..THydrogen-bonded Turntrans-73.8-7.5177.7-59.9177.5000113.6L270 Q271 V272 I283 L586 V589 E590L270-L274 PolarHBondContact O-N 3.03Å; Q271-L274 WeakPolarHBondContact O-CB 3.48Å; Q271-L274 PolarHBondContact O-N 2.87Å; V272-L274 PolarHBondContact O-N 3.09Å; L274-I283 HydrophobicContact CD2-CD1 3.49Å; L274-I283 VanDerWaalsContact CD2-CD1 3.49Å; L274-L586 HydrophobicContact CD2-CB 4.18Å; L274-L586 HydrophobicContact CD2-CD2 4.1Å; L274-L586 HydrophobicContact CG-CD2 4.23Å; L274-V589 HydrophobicContact CD1-CB 4.28Å; L274-V589 HydrophobicContact CD1-CG1 3.66Å; L274-E590 HydrophobicContact CD2-CG 4.07Å
275T88.9Confident88.9Confident114 Ų11465.4 Ų65.470%0.69933%0.331SS*.THydrogen-bonded Turntrans-81.2-18.7172.767.90000112.9V272 F273V272-T275 WeakPolarHBondContact O-CB 3.2Å; V272-T275 PolarHBondContact O-N 3.17Å; V272-T275 VanDerWaalsContact O-N 3.08Å; V272-T275 PolarHBondContact O-OG1 3.23Å; F273-T275 PolarHBondContact O-N 3.05Å
276D91.8Very high90.4Very high66 Ų6662.9 Ų62.935%0.35331%0.314SS..  trans-80.2125.4176.2-175.6-58.9000110.4F273 H278 I279 K280F273-D276 PolarHBondContact O-N 3.23Å; D276-H278 WeakPolarHBondContact OD1-CA 3.28Å; D276-H278 WeakPolarHBondContact OD1-CB 3.26Å; D276-H278 PolarHBondContact OD1-N 3.46Å; D276-I279 HydrophobicContact CB-CB 4.01Å; D276-I279 HydrophobicContact CB-CD1 3.91Å; D276-I279 HydrophobicContact CB-CG1 3.97Å; D276-I279 PolarHBondContact OD1-N 3.3Å; D276-K280 WeakPolarHBondContact O-CB 3.06Å; D276-K280 PolarHBondContact O-N 2.63Å
277V93.8Very high91.4Very high102 Ų10261.3 Ų61.362%0.61830%0.304SS*.Hα-helixtrans-65.4-42.9-175.6178.90000111.6K280 E281V277-K280 PolarHBondContact O-N 3.15Å; V277-E281 WeakPolarHBondContact O-CG 3.4Å; V277-E281 PolarHBondContact O-N 3.03Å
278H94.1Very high92.4Very high95 Ų9559.5 Ų59.544%0.4430%0.303SS..Hα-helixtrans-65.5-46.7-179.9174.772.7000110.6D276 K280 E281 V282 E568D276-H278 WeakPolarHBondContact OD1-CA 3.28Å; D276-H278 WeakPolarHBondContact OD1-CB 3.26Å; D276-H278 PolarHBondContact OD1-N 3.46Å; H278-K280 VanDerWaalsContact C-N 3.26Å; H278-K280 PolarHBondContact O-N 3.26Å; H278-E281 PolarHBondContact O-N 3.03Å; H278-V282 WeakPolarHBondContact O-CG2 3.11Å; H278-V282 PolarHBondContact O-N 3.19Å; H278-E568 IonicContact NE2-OE1 3.37Å; H278-E568 IonicContact NE2-OE2 3.25Å; H278-E568 PolarHBondContact NE2-OE2 3.22Å
279I93.8Very high93.3Very high45 Ų4555 Ų5523%0.23128%0.284CS..Hα-helixtrans-58.5-43177.3-66.1-177.9000110.4F273 D276 V282 I283 L586F273-I279 HydrophobicContact CB-CD1 4.38Å; F273-I279 HydrophobicContact CB-CG2 4.43Å; F273-I279 HydrophobicContact CD1-CD1 3.89Å; D276-I279 HydrophobicContact CB-CB 4.01Å; D276-I279 HydrophobicContact CB-CD1 3.91Å; D276-I279 HydrophobicContact CB-CG1 3.97Å; D276-I279 PolarHBondContact OD1-N 3.3Å; I279-V282 PolarHBondContact O-N 3.35Å; I279-I283 HydrophobicContact CG2-CD1 3.59Å; I279-I283 HydrophobicContact CG2-CG1 4.31Å; I279-I283 VanDerWaalsContact O-CD1 3.3Å; I279-I283 WeakPolarHBondContact O-CD1 3.13Å; I279-I283 WeakPolarHBondContact O-CG1 3.25Å; I279-I283 PolarHBondContact O-N 2.95Å; I279-L586 HydrophobicContact CG2-CD1 3.9Å
280K95.5Very high94.2Very high105 Ų10554.5 Ų54.546%0.45728%0.281SS..Hα-helixtrans-63.1-41.7178.3-168.4172-174.5173.30112.9D276 V277 H278 I283 Q284D276-K280 WeakPolarHBondContact O-CB 3.06Å; D276-K280 PolarHBondContact O-N 2.63Å; V277-K280 PolarHBondContact O-N 3.15Å; H278-K280 VanDerWaalsContact C-N 3.26Å; H278-K280 PolarHBondContact O-N 3.26Å; K280-I283 PolarHBondContact O-N 2.69Å; K280-Q284 PolarHBondContact O-N 3.34Å
281E97.4Very high94.7Very high106 Ų10655.2 Ų55.250%0.49529%0.286SS..Hα-helixtrans-61.2-45.9174.8-73.6175.9-175.800111.7V277 H278 I283 Q284 Q285V277-E281 WeakPolarHBondContact O-CG 3.4Å; V277-E281 PolarHBondContact O-N 3.03Å; H278-E281 PolarHBondContact O-N 3.03Å; E281-I283 VanDerWaalsContact C-N 3.34Å; E281-I283 PolarHBondContact O-N 3.35Å; E281-Q284 PolarHBondContact O-N 2.85Å; E281-Q285 VanDerWaalsContact O-CG 3.31Å; E281-Q285 WeakPolarHBondContact O-CG 3.33Å; E281-Q285 PolarHBondContact O-N 3.21Å
282V98.2Very high95.4Very high9 Ų954.5 Ų54.56%0.05529%0.287CS..Hα-helixtrans-61.3-41.9176.7174.40000111.2H278 I279 Q285 F286 F560 L564 L583H278-V282 WeakPolarHBondContact O-CG2 3.11Å; H278-V282 PolarHBondContact O-N 3.19Å; I279-V282 PolarHBondContact O-N 3.35Å; V282-Q285 PolarHBondContact O-N 2.66Å; V282-F286 WeakPolarHBondContact O-CB 3.22Å; V282-F286 PolarHBondContact O-N 2.89Å; V282-F560 HydrophobicContact CG1-CZ 4.1Å; V282-F560 WeakPolarHBondContact O-CZ 3.36Å; V282-L564 HydrophobicContact CG1-CD1 3.67Å; V282-L564 HydrophobicContact CG1-CD2 4.03Å; V282-L583 HydrophobicContact CG1-CD1 3.98Å
283I98.3Very high95.9Very high1 Ų150.9 Ų50.91%0.00527%0.265CS..Hα-helixtrans-62.7-45.5176.3-67.8156.5000111.2L274 I279 K280 E281 F286 I287 L583 L586 A587 E590L274-I283 HydrophobicContact CD2-CD1 3.49Å; L274-I283 VanDerWaalsContact CD2-CD1 3.49Å; I279-I283 HydrophobicContact CG2-CD1 3.59Å; I279-I283 HydrophobicContact CG2-CG1 4.31Å; I279-I283 VanDerWaalsContact O-CD1 3.3Å; I279-I283 WeakPolarHBondContact O-CD1 3.13Å; I279-I283 WeakPolarHBondContact O-CG1 3.25Å; I279-I283 PolarHBondContact O-N 2.95Å; K280-I283 PolarHBondContact O-N 2.69Å; E281-I283 VanDerWaalsContact C-N 3.34Å; E281-I283 PolarHBondContact O-N 3.35Å; I283-F286 WeakPolarHBondContact O-CB 3.42Å; I283-F286 PolarHBondContact O-N 2.85Å; I283-I287 HydrophobicContact CG2-CD1 3.81Å; I283-I287 HydrophobicContact CG2-CG1 4.36Å; I283-I287 WeakPolarHBondContact O-CG1 3.31Å; I283-I287 PolarHBondContact O-N 2.95Å; I283-L583 HydrophobicContact CG1-CD1 3.88Å; I283-L586 HydrophobicContact CD1-CB 3.44Å; I283-L586 VanDerWaalsContact CD1-CB 3.44Å; I283-L586 HydrophobicContact CD1-CD1 3.98Å; I283-L586 HydrophobicContact CD1-CG 4.26Å; I283-L586 HydrophobicContact CG1-CB 3.88Å; I283-A587 HydrophobicContact CG2-CB 4.08Å; I283-E590 HydrophobicContact CG2-CB 4.3Å; I283-E590 HydrophobicContact CG2-CG 3.87Å
284Q98.4Very high96.5Very high86 Ų8649.7 Ų49.740%0.40226%0.26SS..Hα-helixtrans-62.8-45.8-180-173.759.356.400110.9K280 E281 F286 I287 D288K280-Q284 PolarHBondContact O-N 3.34Å; E281-Q284 PolarHBondContact O-N 2.85Å; Q284-F286 VanDerWaalsContact C-N 3.29Å; Q284-F286 PolarHBondContact O-N 3.04Å; Q284-I287 PolarHBondContact O-N 2.83Å; Q284-D288 PolarHBondContact NE2-OD1 2.59Å; Q284-D288 PolarHBondContact NE2-OD2 3.02Å; Q284-D288 WeakPolarHBondContact O-CB 3.39Å; Q284-D288 PolarHBondContact O-N 2.85Å
285Q98.6Very high96.9Very high103 Ų10353.6 Ų53.648%0.48128%0.276SS..Hα-helixtrans-59.5-40.7174.9-69174.92700111.8E281 V282 D288 V289 F560E281-Q285 VanDerWaalsContact O-CG 3.31Å; E281-Q285 WeakPolarHBondContact O-CG 3.33Å; E281-Q285 PolarHBondContact O-N 3.21Å; V282-Q285 PolarHBondContact O-N 2.66Å; Q285-D288 PolarHBondContact O-N 3.45Å; Q285-V289 WeakPolarHBondContact O-CG1 3.45Å; Q285-V289 PolarHBondContact O-N 2.97Å; Q285-F560 HydrophobicContact CB-CD2 4.46Å; Q285-F560 HydrophobicContact CB-CE2 3.57Å; Q285-F560 HydrophobicContact CB-CZ 3.93Å
286F98.9Very high97.3Very high1 Ų150.6 Ų50.60%0.00425%0.253CS..Hα-helixtrans-63.5-45.5176.1-178.3-125.6000112.5V282 I283 Q284 D288 V289 L290 L500 F552 V557 F560 L561 L583 L584 A587V282-F286 WeakPolarHBondContact O-CB 3.22Å; V282-F286 PolarHBondContact O-N 2.89Å; I283-F286 WeakPolarHBondContact O-CB 3.42Å; I283-F286 PolarHBondContact O-N 2.85Å; Q284-F286 VanDerWaalsContact C-N 3.29Å; Q284-F286 PolarHBondContact O-N 3.04Å; F286-D288 VanDerWaalsContact C-N 3.3Å; F286-D288 PolarHBondContact O-N 2.91Å; F286-V289 HydrophobicContact CD2-CG1 4.4Å; F286-V289 WeakPolarHBondContact O-CG1 3.31Å; F286-L290 HydrophobicContact CE1-CD2 4.45Å; F286-L290 HydrophobicContact CZ-CD2 4.14Å; F286-L290 VanDerWaalsContact O-CB 3.25Å; F286-L290 WeakPolarHBondContact O-CB 3.42Å; F286-L290 PolarHBondContact O-N 3.3Å; F286-L500 HydrophobicContact CZ-CD1 4.34Å; F286-F552 HydrophobicContact CZ-CE1 4.06Å; F286-V557 HydrophobicContact CE2-CG1 4.35Å; F286-F560 HydrophobicContact CB-CD1 4.37Å; F286-F560 HydrophobicContact CB-CE1 3.5Å; F286-F560 VanDerWaalsContact CB-CE1 3.5Å; F286-F560 HydrophobicContact CB-CZ 3.93Å; F286-F560 AromaticContact CD2-CD1 3.86Å; F286-F560 HydrophobicContact CD2-CD1 3.86Å; F286-F560 AromaticContact CD2-CE1 3.7Å; F286-F560 HydrophobicContact CD2-CE1 3.7Å; F286-F560 AromaticContact CG-CE1 3.99Å; F286-F560 HydrophobicContact CG-CE1 3.99Å; F286-L561 HydrophobicContact CD2-CD2 3.93Å; F286-L561 HydrophobicContact CD2-CG 4.48Å; F286-L561 HydrophobicContact CE2-CD1 4.08Å; F286-L561 HydrophobicContact CE2-CD2 3.72Å; F286-L561 HydrophobicContact CE2-CG 4.08Å; F286-L561 HydrophobicContact CZ-CD2 4.47Å; F286-L583 HydrophobicContact CB-CD1 4.28Å; F286-L583 HydrophobicContact CB-CD2 4.3Å; F286-L583 HydrophobicContact CB-CG 4.39Å; F286-L583 HydrophobicContact CD1-CD1 4.32Å; F286-L583 HydrophobicContact CD1-CD2 4.18Å; F286-L583 HydrophobicContact CD1-CG 3.81Å; F286-L583 HydrophobicContact CD2-CD2 4.3Å; F286-L583 HydrophobicContact CE1-CG 4.28Å; F286-L583 HydrophobicContact CG-CD1 4.48Å; F286-L583 HydrophobicContact CG-CD2 3.99Å; F286-L583 HydrophobicContact CG-CG 4.08Å; F286-L584 HydrophobicContact CE1-CB 4.28Å; F286-L584 HydrophobicContact CE1-CD1 3.87Å; F286-L584 HydrophobicContact CZ-CD1 4.29Å; F286-A587 HydrophobicContact CD1-CB 3.89Å; F286-A587 HydrophobicContact CE1-CB 4.22Å
287I98.9Very high97.5Very high7 Ų747.5 Ų47.54%0.03624%0.237CC..Hα-helixtrans-60.2-44.1175.6-72.1169.7000110I283 Q284 L290 S291 L338 A587 E590 L591I283-I287 HydrophobicContact CG2-CD1 3.81Å; I283-I287 HydrophobicContact CG2-CG1 4.36Å; I283-I287 WeakPolarHBondContact O-CG1 3.31Å; I283-I287 PolarHBondContact O-N 2.95Å; Q284-I287 PolarHBondContact O-N 2.83Å; I287-L290 PolarHBondContact O-N 2.83Å; I287-S291 WeakPolarHBondContact O-CA 3.48Å; I287-S291 WeakPolarHBondContact O-CB 3.26Å; I287-S291 PolarHBondContact O-N 2.96Å; I287-L338 HydrophobicContact CG2-CD2 4.45Å; I287-A587 HydrophobicContact CD1-CB 4.13Å; I287-A587 HydrophobicContact CG1-CB 3.78Å; I287-E590 HydrophobicContact CD1-CB 3.76Å; I287-L591 HydrophobicContact CD1-CD2 4.27Å; I287-L591 HydrophobicContact CD1-CG 4.17Å; I287-L591 HydrophobicContact CG1-CD2 4.49Å; I287-L591 HydrophobicContact CG1-CG 4.44Å; I287-L591 HydrophobicContact CG2-CD2 3.95Å
288D98.8Very high97.6Very high77 Ų7742.7 Ų42.741%0.41221%0.207SC..Hα-helixtrans-65.5-49-177-68.5-21.6000111.4Q284 Q285 F286 L290 S291 V292Q284-D288 PolarHBondContact NE2-OD1 2.59Å; Q284-D288 PolarHBondContact NE2-OD2 3.02Å; Q284-D288 WeakPolarHBondContact O-CB 3.39Å; Q284-D288 PolarHBondContact O-N 2.85Å; Q285-D288 PolarHBondContact O-N 3.45Å; F286-D288 VanDerWaalsContact C-N 3.3Å; F286-D288 PolarHBondContact O-N 2.91Å; D288-L290 PolarHBondContact O-N 2.88Å; D288-S291 WeakPolarHBondContact O-CB 3.4Å; D288-S291 PolarHBondContact O-N 3.35Å; D288-V292 WeakPolarHBondContact O-CG2 3.38Å; D288-V292 PolarHBondContact O-N 3.47Å
289V98.8Very high97.3Very high27 Ų2741.6 Ų41.616%0.16420%0.204CC..Hα-helixtrans-64.9-40.1179.1720000111.6Q285 F286 V292 A293 N556 V557 F560Q285-V289 WeakPolarHBondContact O-CG1 3.45Å; Q285-V289 PolarHBondContact O-N 2.97Å; F286-V289 HydrophobicContact CD2-CG1 4.4Å; F286-V289 WeakPolarHBondContact O-CG1 3.31Å; V289-V292 PolarHBondContact O-N 2.9Å; V289-A293 PolarHBondContact O-N 3.19Å; V289-N556 HydrophobicContact CG2-CB 3.75Å; V289-V557 HydrophobicContact CG1-CG2 4.23Å; V289-V557 HydrophobicContact CG2-CG2 4.02Å; V289-F560 HydrophobicContact CG1-CB 4.09Å; V289-F560 HydrophobicContact CG1-CD1 4.05Å; V289-F560 HydrophobicContact CG1-CG 4.01Å
290L98.9Very high96.8Very high2 Ų241.8 Ų41.81%0.0121%0.209CC..Hα-helixtrans-69.7-37.8176.7-173.861000111.9F286 I287 D288 A293 V294 V334 L338 P551 F552 V557F286-L290 HydrophobicContact CE1-CD2 4.45Å; F286-L290 HydrophobicContact CZ-CD2 4.14Å; F286-L290 VanDerWaalsContact O-CB 3.25Å; F286-L290 WeakPolarHBondContact O-CB 3.42Å; F286-L290 PolarHBondContact O-N 3.3Å; I287-L290 PolarHBondContact O-N 2.83Å; D288-L290 PolarHBondContact O-N 2.88Å; L290-A293 WeakPolarHBondContact O-CB 3.38Å; L290-A293 PolarHBondContact O-N 2.98Å; L290-V294 WeakPolarHBondContact O-CG2 3.46Å; L290-V294 PolarHBondContact O-N 3.46Å; L290-V334 HydrophobicContact CD2-CG1 3.8Å; L290-L338 HydrophobicContact CB-CD1 4.1Å; L290-L338 HydrophobicContact CD2-CD1 3.76Å; L290-L338 HydrophobicContact CG-CD1 3.63Å; L290-P551 HydrophobicContact CD1-CB 3.94Å; L290-F552 HydrophobicContact CD1-CD1 4.09Å; L290-F552 HydrophobicContact CD1-CE1 4.13Å; L290-F552 HydrophobicContact CD1-CG 4.46Å; L290-F552 HydrophobicContact CD2-CD1 4.46Å; L290-F552 HydrophobicContact CD2-CE1 3.72Å; L290-F552 HydrophobicContact CD2-CZ 3.95Å; L290-V557 HydrophobicContact CB-CG2 4.47Å; L290-V557 HydrophobicContact CD1-CG1 4.4Å; L290-V557 HydrophobicContact CD1-CG2 4.18Å
291S98.8Very high96.4Very high15 Ų1537.5 Ų37.511%0.10519%0.191CC..Hα-helixtrans-61.4-44.5174.8-179.20000111.1I287 D288 V294 K295 H342I287-S291 WeakPolarHBondContact O-CA 3.48Å; I287-S291 WeakPolarHBondContact O-CB 3.26Å; I287-S291 PolarHBondContact O-N 2.96Å; D288-S291 WeakPolarHBondContact O-CB 3.4Å; D288-S291 PolarHBondContact O-N 3.35Å; S291-V294 PolarHBondContact O-N 2.93Å; S291-K295 VanDerWaalsContact O-CB 3.32Å; S291-K295 WeakPolarHBondContact O-CB 3.36Å; S291-K295 PolarHBondContact O-N 3.07Å; S291-H342 PolarHBondContact O-NE2 2.8Å; S291-H342 VanDerWaalsContact O-NE2 3.16Å; S291-H342 PolarHBondContact OG-CE1 3.31Å; S291-H342 PolarHBondContact OG-NE2 3.16Å
292V98.6Very high95.6Very high69 Ų6935.2 Ų35.242%0.41819%0.186SC..Hα-helixtrans-62.5-42.5173.8170.90000111.3D288 V289 V294 K295 K296D288-V292 WeakPolarHBondContact O-CG2 3.38Å; D288-V292 PolarHBondContact O-N 3.47Å; V289-V292 PolarHBondContact O-N 2.9Å; V292-V294 PolarHBondContact O-N 3.43Å; V292-K295 WeakPolarHBondContact O-CB 3.48Å; V292-K295 PolarHBondContact O-N 2.73Å; V292-K296 HydrophobicContact CG1-CD 4.34Å; V292-K296 WeakPolarHBondContact O-CG 3.27Å; V292-K296 PolarHBondContact O-N 2.79Å
293A98.6Very high94.9Very high0 Ų038.2 Ų38.20%020%0.196CC..Hα-helixtrans-61-43.1176.100000112.4V289 L290 R297 D554 V557V289-A293 PolarHBondContact O-N 3.19Å; L290-A293 WeakPolarHBondContact O-CB 3.38Å; L290-A293 PolarHBondContact O-N 2.98Å; A293-R297 VanDerWaalsContact O-CD 3.29Å; A293-R297 WeakPolarHBondContact O-CD 3.31Å; A293-R297 WeakPolarHBondContact O-CG 3.37Å; A293-R297 PolarHBondContact O-N 3.31Å; A293-R297 PolarHBondContact O-NH1 3.5Å; A293-D554 HydrophobicContact CB-CB 3.54Å; A293-V557 HydrophobicContact CB-CG2 3.63Å
294V98.7Very high93.3Very high0 Ų041.9 Ų41.90%024%0.235CC..Hα-helixtrans-65.1-46.5174.9173.60000110.7L290 S291 V292 K296 R297 V298 L338 A339 L491 P551L290-V294 WeakPolarHBondContact O-CG2 3.46Å; L290-V294 PolarHBondContact O-N 3.46Å; S291-V294 PolarHBondContact O-N 2.93Å; V292-V294 PolarHBondContact O-N 3.43Å; V294-K296 PolarHBondContact O-N 2.99Å; V294-R297 CarbonylContact O-C 3.55Å; V294-R297 WeakPolarHBondContact O-CA 3.45Å; V294-R297 WeakPolarHBondContact O-CB 3.41Å; V294-R297 PolarHBondContact O-N 2.91Å; V294-V298 PolarHBondContact O-N 3.01Å; V294-L338 HydrophobicContact CB-CB 4.27Å; V294-L338 HydrophobicContact CG1-CB 4.26Å; V294-L338 HydrophobicContact CG2-CB 4.05Å; V294-L338 HydrophobicContact CG2-CD1 4.39Å; V294-A339 HydrophobicContact CG1-CB 4Å; V294-L491 HydrophobicContact CG1-CD1 4.45Å; V294-P551 HydrophobicContact CG2-CB 3.73Å; V294-P551 HydrophobicContact CG2-CG 3.93Å
295K98.1Very high91Very high96 Ų9646.1 Ų46.142%0.41725%0.254SS..Hα-helixtrans-51.6-54.6177.4-177.1176.9178.8178.10111.9S291 V292 R297 V298 L299 H342S291-K295 VanDerWaalsContact O-CB 3.32Å; S291-K295 WeakPolarHBondContact O-CB 3.36Å; S291-K295 PolarHBondContact O-N 3.07Å; V292-K295 WeakPolarHBondContact O-CB 3.48Å; V292-K295 PolarHBondContact O-N 2.73Å; K295-R297 PolarHBondContact O-N 3.04Å; K295-R297 VanDerWaalsContact O-N 3.11Å; K295-V298 PolarHBondContact O-N 2.83Å; K295-L299 HydrophobicContact CD-CD1 4.09Å; K295-L299 HydrophobicContact CG-CD1 3.43Å; K295-L299 VanDerWaalsContact CG-CD1 3.43Å; K295-L299 HydrophobicContact CG-CG 3.87Å; K295-L299 WeakPolarHBondContact O-CG 3.04Å; K295-L299 PolarHBondContact O-N 3.2Å; K295-L299 VanDerWaalsContact O-N 3.12Å; K295-H342 HydrophobicContact CB-CB 4.32Å; K295-H342 HydrophobicContact CG-CB 4.34Å
296K95.6Very high88.3Confident50 Ų5048.2 Ų48.222%0.21727%0.269CS..Hα-helixtrans-55-33.1178.5-69.9176.7-178.7-179.50112.5F80 V292 V294F80-K296 HydrophobicContact CB-CB 4.28Å; F80-K296 HydrophobicContact CB-CD 4.35Å; F80-K296 HydrophobicContact CD1-CB 4.29Å; F80-K296 WeakPolarHBondContact CD1-O 3.35Å; F80-K296 WeakPolarHBondContact CE1-O 3.35Å; F80-K296 HydrophobicContact CG-CB 4.44Å; V292-K296 HydrophobicContact CG1-CD 4.34Å; V292-K296 WeakPolarHBondContact O-CG 3.27Å; V292-K296 PolarHBondContact O-N 2.79Å; V294-K296 PolarHBondContact O-N 2.99Å
297R96.8Very high85.6Confident2 Ų253.4 Ų53.41%0.00830%0.296CS..Hα-helixtrans-84.2-4.6-177.9-71.4165178.7650.9114.5F80 A293 V294 K295 L491 R549 F550 D554F80-R297 HydrophobicContact CD2-CG 4.46Å; F80-R297 HydrophobicContact CE1-CG 4.34Å; F80-R297 HydrophobicContact CE2-CG 3.94Å; F80-R297 HydrophobicContact CZ-CG 3.89Å; A293-R297 VanDerWaalsContact O-CD 3.29Å; A293-R297 WeakPolarHBondContact O-CD 3.31Å; A293-R297 WeakPolarHBondContact O-CG 3.37Å; A293-R297 PolarHBondContact O-N 3.31Å; A293-R297 PolarHBondContact O-NH1 3.5Å; V294-R297 CarbonylContact O-C 3.55Å; V294-R297 WeakPolarHBondContact O-CA 3.45Å; V294-R297 WeakPolarHBondContact O-CB 3.41Å; V294-R297 PolarHBondContact O-N 2.91Å; K295-R297 PolarHBondContact O-N 3.04Å; K295-R297 VanDerWaalsContact O-N 3.11Å; R297-L491 HydrophobicContact CB-CD2 4.14Å; R297-R549 VanDerWaalsContact C-NH1 3.32Å; R297-R549 HydrophobicContact CB-CB 4.25Å; R297-R549 HydrophobicContact CG-CB 4.1Å; R297-R549 VanDerWaalsContact O-CD 3.25Å; R297-R549 WeakPolarHBondContact O-CD 3.26Å; R297-R549 PolarHBondContact O-NH1 3.07Å; R297-F550 VanDerWaalsContact NE-C 3.27Å; R297-F550 PolarHBondContact NE-O 2.77Å; R297-F550 VanDerWaalsContact NE-O 3.09Å; R297-F550 PolarHBondContact NH2-O 2.89Å; R297-D554 IonicContact CZ-OD2 2.76Å; R297-D554 IonicContact NH1-OD2 3.09Å; R297-D554 PolarHBondContact NH1-OD2 3.44Å; R297-D554 VanDerWaalsContact NH2-CB 3.3Å; R297-D554 IonicContact NH2-OD2 3.34Å; R297-D554 PolarHBondContact NH2-OD2 3.28Å
298V95.8Very high82.9Confident0 Ų057.6 Ų57.60%032%0.322CS..Hα-helixtrans-126.7-12.6-179.6-570000114.3V294 K295 R303 V322 H342 I343 L491V294-V298 PolarHBondContact O-N 3.01Å; K295-V298 PolarHBondContact O-N 2.83Å; V298-R303 PolarHBondContact O-NH2 2.82Å; V298-V322 HydrophobicContact CB-CG2 4.23Å; V298-V322 HydrophobicContact CG1-CG1 4.18Å; V298-V322 HydrophobicContact CG1-CG2 4.07Å; V298-H342 HydrophobicContact CG2-CB 3.7Å; V298-I343 HydrophobicContact CB-CD1 4.38Å; V298-I343 HydrophobicContact CB-CG1 3.94Å; V298-I343 HydrophobicContact CG1-CD1 4.24Å; V298-I343 HydrophobicContact CG1-CG1 4.3Å; V298-I343 HydrophobicContact CG2-CG1 3.98Å; V298-L491 HydrophobicContact CG1-CD1 4.03Å; V298-L491 HydrophobicContact CG1-CD2 4.35Å
299L87.9Confident80.4Confident72 Ų7258.3 Ų58.338%0.37734%0.338SS..Hα-helixtrans-75.8-57.2-174.5-77.4-178000114.3K295 L301 R303K295-L299 HydrophobicContact CD-CD1 4.09Å; K295-L299 HydrophobicContact CG-CD1 3.43Å; K295-L299 VanDerWaalsContact CG-CD1 3.43Å; K295-L299 HydrophobicContact CG-CG 3.87Å; K295-L299 WeakPolarHBondContact O-CG 3.04Å; K295-L299 PolarHBondContact O-N 3.2Å; K295-L299 VanDerWaalsContact O-N 3.12Å; L299-L301 PolarHBondContact O-N 3.47Å; L299-R303 PolarHBondContact O-NH1 2.85Å
300C82.9Confident77.6Confident49 Ų4964.4 Ų64.433%0.33137%0.37SS..SBendtrans-80.836.3-167.7-520000114.1L56L56-C300 VanDerWaalsContact O-O 3.09Å
301L86.6Confident75Confident15 Ų1569.8 Ų69.88%0.07940%0.395CS..  trans-88.1145.1179.5-59.3179.5000111L299 R303 N321 V322 V489L299-L301 PolarHBondContact O-N 3.47Å; L301-R303 PolarHBondContact O-N 2.93Å; L301-N321 HydrophobicContact CD1-CB 4.24Å; L301-V322 HydrophobicContact CD1-CG2 3.4Å; L301-V489 HydrophobicContact CD1-CB 4.43Å; L301-V489 HydrophobicContact CD1-CG2 4.27Å; L301-V489 HydrophobicContact CD2-CG2 3.55Å
302P82Confident72.4Confident59 Ų5974.8 Ų74.838%0.38343%0.425SS..  trans-72.798175.3-7.227.4000107.4L56L56-P302 VanDerWaalsContact O-CD 3.26Å; L56-P302 WeakPolarHBondContact O-CD 3.06Å
303R83.6Confident69.6Low71 Ų7176.8 Ų76.827%0.26844%0.442SS..  trans-88.3112167.9-63.7-179.617980.85.2105V298 L299 L301 E305 E347V298-R303 PolarHBondContact O-NH2 2.82Å; L299-R303 PolarHBondContact O-NH1 2.85Å; L301-R303 PolarHBondContact O-N 2.93Å; R303-E305 PolarHBondContact O-N 2.94Å; R303-E347 IonicContact CZ-OE2 3.72Å; R303-E347 IonicContact NE-OE2 2.6Å; R303-E347 PolarHBondContact NE-OE2 3.19Å; R303-E347 IonicContact NH2-OE2 2.97Å
304G64.6Low67.1Low79 Ų7983.5 Ų83.581%0.81447%0.471SS*.  trans-48.6113.8-173.600000111.5
305E50Low64.5Low174 Ų17490.7 Ų90.781%0.81351%0.507SS*.  trans-74.8140.5169.7-68.7-175.8159.400108.5R303R303-E305 PolarHBondContact O-N 2.94Å
306N40.5Very low62Low148 Ų14892 Ų9279%0.79153%0.527SS*.  trans90.265.5179.4-47.7-50000116.9
307L43.9Very low60.3Low110 Ų11094.6 Ų94.658%0.57654%0.543SS*.  trans-79.1113.8136.2-66.7167.7000105.9E311L307-E311 HydrophobicContact CD2-CB 4.36Å; L307-E311 WeakPolarHBondContact CD2-OE2 3.02Å
308T40.9Very low59.2Low95 Ų9599.6 Ų99.658%0.58356%0.562SS**  trans-59153.2172.959.30000109.9N310 E311T308-N310 PolarHBondContact O-N 3.37Å; T308-E311 PolarHBondContact O-N 3.38Å
309A46.7Very low58.9Low91 Ų91106.8 Ų106.875%0.75259%0.593SS**THydrogen-bonded Turntrans-56.3-4.8-175.700000115.7V312A309-V312 WeakPolarHBondContact O-CG2 3.48Å
310N40.7Very low59.2Low155 Ų155103.4 Ų103.483%0.82958%0.575SS**THydrogen-bonded Turntrans-91.9-2.5175.3-84-8.3000115.1T308T308-N310 PolarHBondContact O-N 3.37Å
311E44.5Very low59.7Low115 Ų115103.2 Ų103.254%0.53757%0.571SS.*  trans-10618.6178-67.9-176.6148.900113.7L307 T308 S313L307-E311 HydrophobicContact CD2-CB 4.36Å; L307-E311 WeakPolarHBondContact CD2-OE2 3.02Å; T308-E311 PolarHBondContact O-N 3.38Å; E311-S313 PolarHBondContact O-N 3.42Å; E311-S313 VanDerWaalsContact O-N 3.08Å
312V43Very low60.3Low120 Ų120102.5 Ų102.573%0.72757%0.567SS**THydrogen-bonded Turntrans-66.6-7.4176-175.40000112.3A309A309-V312 WeakPolarHBondContact O-CG2 3.48Å
313S39.8Very low61.1Low112 Ų11299.7 Ų99.778%0.78355%0.549SS*.THydrogen-bonded Turntrans-86.7-0.6-174.7-172.80000116E311E311-S313 PolarHBondContact O-N 3.42Å; E311-S313 VanDerWaalsContact O-N 3.08Å
314K46.3Very low61.8Low141 Ų14196.3 Ų96.361%0.61354%0.536SS*.  trans-135.182176.2-71.8-171-176.8176.50112.7C316 D317K314-C316 PolarHBondContact O-N 3.29Å; K314-D317 HydrophobicContact CB-CB 4.49Å; K314-D317 WeakPolarHBondContact CD-OD2 3.36Å; K314-D317 IonicContact NZ-OD2 3.67Å; K314-D317 PolarHBondContact O-N 3.15Å
315M44.6Very low63.4Low151 Ų15193.4 Ų93.474%0.74450%0.502SS*.G310 helixtrans-55.4-17.2163.2-71.4-174.869.600112.9
316C45.7Very low65.7Low123 Ų12385.4 Ų85.483%0.83146%0.464SS*.G310 helixtrans-80-9.1-176.1-126.50000116K314K314-C316 PolarHBondContact O-N 3.29Å
317D58.7Low68.4Low105 Ų10579.9 Ų79.956%0.56144%0.438SS*.G310 helixtrans-109.410.4-172.3-78.6-24.4000114.2K314 K319K314-D317 HydrophobicContact CB-CB 4.49Å; K314-D317 WeakPolarHBondContact CD-OD2 3.36Å; K314-D317 IonicContact NZ-OD2 3.67Å; K314-D317 PolarHBondContact O-N 3.15Å; D317-K319 PolarHBondContact O-N 3.04Å
318R75.3Confident70.9Confident107 Ų10774.7 Ų74.740%0.40441%0.41SS..PPolyproline II helixtrans-72.2128.7177.8-76.1-172.2166.2160.3-16.4111.7D346 P348R318-D346 VanDerWaalsContact CD-O 3.28Å; R318-D346 WeakPolarHBondContact CD-O 3.45Å; R318-D346 IonicContact CZ-OD2 3.37Å; R318-D346 IonicContact NE-OD2 3.62Å; R318-D346 IonicContact NH1-OD2 3.77Å; R318-D346 PolarHBondContact NH1-OD2 3.43Å; R318-D346 IonicContact NH2-OD2 3.45Å; R318-D346 PolarHBondContact NH2-OD2 2.78Å; R318-P348 WeakPolarHBondContact O-CG 3.24Å
319K88.8Confident73.6Confident151 Ų15171 Ų7166%0.65739%0.392SS*.PPolyproline II helixtrans-85.1140.2-179.8-69-179.9-175.8175.30110.6D317 S486D317-K319 PolarHBondContact O-N 3.04Å; K319-S486 WeakPolarHBondContact CB-OG 3.25Å
320A93.6Very high76.1Confident0 Ų067 Ų670%036%0.358CS..PPolyproline II helixtrans-71129.7168.900000110.1P348 D350 S486 A487A320-P348 WeakPolarHBondContact CA-O 3.5Å; A320-P348 HydrophobicContact CB-CB 4.39Å; A320-P348 WeakPolarHBondContact CB-O 3.49Å; A320-D350 HydrophobicContact CB-CB 4.2Å; A320-D350 VanDerWaalsContact CB-CG 3.42Å; A320-D350 WeakPolarHBondContact CB-OD1 3.39Å; A320-S486 PolarHBondContact O-OG 3.3Å; A320-A487 WeakPolarHBondContact O-CA 3.47Å; A320-A487 PolarHBondContact O-N 3.07Å
321N94.9Very high78.8Confident45 Ų4560.8 Ų60.824%0.24132%0.324CS..SBendtrans-92.4-20.2169.5-55.6-75.4000111.9L301 E347 V489L301-N321 HydrophobicContact CD1-CB 4.24Å; N321-E347 WeakPolarHBondContact CB-OE1 3.49Å; N321-E347 PolarHBondContact N-OE1 3.42Å; N321-E347 PolarHBondContact ND2-OE1 3.34Å; N321-V489 PolarHBondContact O-N 3.05Å
322V97.9Very high81.4Confident0 Ų055.6 Ų55.60%030%0.301CS..EExtended strand (participates in β ladder)trans-118131.1179.2-176.60000110.5V298 L301 I343 D350 L491V298-V322 HydrophobicContact CB-CG2 4.23Å; V298-V322 HydrophobicContact CG1-CG1 4.18Å; V298-V322 HydrophobicContact CG1-CG2 4.07Å; L301-V322 HydrophobicContact CD1-CG2 3.4Å; V322-I343 HydrophobicContact CB-CD1 3.77Å; V322-I343 HydrophobicContact CG1-CD1 4Å; V322-I343 HydrophobicContact CG2-CD1 3.91Å; V322-I343 HydrophobicContact CG2-CG1 4.5Å; V322-D350 PolarHBondContact O-N 2.81Å; V322-L491 HydrophobicContact CG1-CD1 4.05Å; V322-L491 HydrophobicContact CG1-CG 3.9Å
323A98.6Very high84Confident0 Ų049.9 Ų49.90%027%0.266CS..EExtended strand (participates in β ladder)trans-116.7161.4168.700000110.8D350 L352 A487 V489 V490 L491A323-D350 CarbonylContact C-O 3.5Å; A323-D350 WeakPolarHBondContact CA-O 3.31Å; A323-D350 HydrophobicContact CB-CB 3.84Å; A323-L352 HydrophobicContact CB-CD1 3.76Å; A323-L352 HydrophobicContact CB-CD2 4.41Å; A323-L352 HydrophobicContact CB-CG 3.97Å; A323-A487 HydrophobicContact CB-CB 3.66Å; A323-V489 PolarHBondContact N-O 3.02Å; A323-V490 HydrophobicContact CB-CG2 4.39Å; A323-V490 CarbonylContact O-C 3.6Å; A323-V490 VanDerWaalsContact O-CA 3.32Å; A323-V490 WeakPolarHBondContact O-CA 3.44Å; A323-L491 PolarHBondContact O-N 3.48Å
324I98.8Very high86.8Confident1 Ų144.6 Ų44.61%0.00523%0.229CC..EExtended strand (participates in β ladder)trans-129.2129.6177.5-54.4180000108.1F326 I335 A336 A339 I349 D350 L351 L352 L491I324-F326 HydrophobicContact CG2-CB 4.45Å; I324-F326 PolarHBondContact O-N 2.83Å; I324-F326 VanDerWaalsContact O-N 3.12Å; I324-I335 HydrophobicContact CD1-CG2 4.26Å; I324-I335 HydrophobicContact CG2-CG2 4.26Å; I324-A336 VanDerWaalsContact CD1-CA 3.41Å; I324-A336 HydrophobicContact CD1-CB 3.67Å; I324-A339 HydrophobicContact CD1-CB 4.26Å; I324-I349 HydrophobicContact CD1-CG2 3.86Å; I324-I349 HydrophobicContact CG1-CG2 4.1Å; I324-D350 PolarHBondContact N-O 3.02Å; I324-L351 HydrophobicContact CB-CD2 4.17Å; I324-L351 HydrophobicContact CD1-CD2 4.14Å; I324-L351 HydrophobicContact CG1-CD2 4.47Å; I324-L352 PolarHBondContact O-N 3.37Å; I324-L491 HydrophobicContact CG1-CB 4.24Å; I324-L491 HydrophobicContact CG1-CD1 4.38Å
325L98.6Very high89.3Confident17 Ų1737.9 Ų37.99%0.08920%0.2CC..EExtended strand (participates in β ladder)trans-67.8109.7165.3-65-173.5000108.4L352 V464 A467 V490 L491 T492 I541L325-L352 HydrophobicContact CD2-CB 4.36Å; L325-L352 HydrophobicContact CD2-CD1 4.4Å; L325-V464 HydrophobicContact CD1-CG1 4.13Å; L325-A467 HydrophobicContact CD2-CB 3.78Å; L325-V490 HydrophobicContact CD1-CG1 4.4Å; L325-V490 HydrophobicContact CD2-CG1 3.78Å; L325-V490 HydrophobicContact CG-CG1 3.58Å; L325-L491 PolarHBondContact N-O 3.47Å; L325-T492 HydrophobicContact CD1-CG2 3.91Å; L325-T492 HydrophobicContact CG-CG2 4.33Å; L325-I541 HydrophobicContact CD1-CD1 4.27Å
326F98.5Very high91.9Very high6 Ų630.7 Ų30.73%0.02616%0.164CC..  trans-125.9112.2-160.3-174.1-96.1000111.9I324 M333 A336 L351 L352 N353 G409 L416 F427I324-F326 HydrophobicContact CG2-CB 4.45Å; I324-F326 PolarHBondContact O-N 2.83Å; I324-F326 VanDerWaalsContact O-N 3.12Å; F326-M333 HydrophobicContact CE2-CG 4.35Å; F326-M333 HydrophobicContact CE2-SD 3.49Å; F326-M333 WeakPolarHBondContact CE2-SD 3.36Å; F326-M333 HydrophobicContact CZ-SD 3.37Å; F326-M333 WeakPolarHBondContact CZ-SD 3.46Å; F326-A336 HydrophobicContact CE2-CB 4.36Å; F326-L351 HydrophobicContact CB-CB 3.88Å; F326-L351 HydrophobicContact CB-CD2 4.31Å; F326-L351 HydrophobicContact CD1-CB 3.92Å; F326-L351 HydrophobicContact CD1-CD1 4.15Å; F326-L351 HydrophobicContact CD1-CG 4.47Å; F326-L351 HydrophobicContact CD2-CD1 4.39Å; F326-L351 HydrophobicContact CD2-CD2 3.84Å; F326-L351 HydrophobicContact CD2-CG 4.48Å; F326-L351 HydrophobicContact CE1-CD1 4.01Å; F326-L351 HydrophobicContact CE2-CD1 4.27Å; F326-L351 HydrophobicContact CE2-CD2 4.29Å; F326-L351 HydrophobicContact CG-CB 3.86Å; F326-L351 HydrophobicContact CG-CD1 4.32Å; F326-L351 HydrophobicContact CG-CD2 4.03Å; F326-L351 HydrophobicContact CG-CG 4.29Å; F326-L351 HydrophobicContact CZ-CD1 4.06Å; F326-L352 PolarHBondContact N-O 2.94Å; F326-N353 WeakPolarHBondContact O-CB 3.32Å; F326-N353 PolarHBondContact O-ND2 3.2Å; F326-G409 WeakPolarHBondContact CE1-O 3.35Å; F326-L416 HydrophobicContact CE2-CD1 3.74Å; F326-L416 HydrophobicContact CZ-CD1 3.78Å; F326-F427 HydrophobicContact CD1-CD2 4.1Å; F326-F427 AromaticContact CD1-CE2 3.77Å; F326-F427 HydrophobicContact CD1-CE2 3.77Å; F326-F427 HydrophobicContact CE1-CD2 4.23Å; F326-F427 AromaticContact CE1-CE2 3.95Å; F326-F427 HydrophobicContact CE1-CE2 3.95Å
327S96.9Very high94.4Very high33 Ų3325.1 Ų25.123%0.23113%0.127CC..  trans-102.7-9.9176.562.40000113.2G329 S332 T408 G409S327-G329 PolarHBondContact O-N 3.38Å; S327-G329 PolarHBondContact OG-N 2.92Å; S327-G329 VanDerWaalsContact OG-N 3.11Å; S327-S332 PolarHBondContact N-OG 3.37Å; S327-T408 CarbonylContact O-C 3.52Å; S327-T408 PolarHBondContact O-OG1 2.92Å; S327-G409 PolarHBondContact O-N 3.03Å
328G96.8Very high96.3Very high0 Ų020.1 Ų20.10%010%0.1CC..SBendtrans74.62.1-165.300000113.6S332G328-S332 PolarHBondContact N-OG 2.8Å
329G97.1Very high97.4Very high19 Ų1915 Ų1520%0.1968%0.081CC..SBendtrans-71.1157.716700000111.4S327 D331 S332 M333S327-G329 PolarHBondContact O-N 3.38Å; S327-G329 PolarHBondContact OG-N 2.92Å; S327-G329 VanDerWaalsContact OG-N 3.11Å; G329-D331 VanDerWaalsContact C-N 3.27Å; G329-D331 PolarHBondContact O-N 3Å; G329-D331 VanDerWaalsContact O-N 3.13Å; G329-S332 PolarHBondContact O-N 3.37Å; G329-S332 VanDerWaalsContact O-N 3.11Å; G329-S332 PolarHBondContact O-OG 3.42Å; G329-M333 WeakPolarHBondContact O-CG 3.43Å; G329-M333 PolarHBondContact O-N 2.85Å
330I97.9Very high97.9Very high7 Ų78.9 Ų8.94%0.0366%0.055CC..Hα-helixtrans-55.3-37.3-169.5-164.9166.8000114.7S332 M333 V334 K581 L584 R585 A588 A597I330-S332 PolarHBondContact O-N 3.44Å; I330-M333 PolarHBondContact O-N 2.84Å; I330-V334 HydrophobicContact CG1-CG2 4.18Å; I330-V334 WeakPolarHBondContact O-CG2 3.12Å; I330-V334 PolarHBondContact O-N 3.49Å; I330-K581 HydrophobicContact CG2-CD 4.24Å; I330-L584 HydrophobicContact CD1-CG 4.35Å; I330-L584 HydrophobicContact CG1-CG 4.25Å; I330-L584 HydrophobicContact CG2-CD2 4.01Å; I330-R585 VanDerWaalsContact CD1-CA 3.46Å; I330-R585 HydrophobicContact CD1-CB 4.02Å; I330-R585 HydrophobicContact CD1-CG 3.48Å; I330-R585 VanDerWaalsContact CD1-CG 3.48Å; I330-A588 HydrophobicContact CD1-CB 3.75Å; I330-A588 HydrophobicContact CG1-CB 3.96Å; I330-A597 HydrophobicContact CD1-CB 4.47Å
331D98.3Very high98Very high24 Ų2415 Ų1513%0.1288%0.078CC..Hα-helixtrans-61.1-48.4-179.6-41.5-45000111G329 I335 A496 F552 K581 L584G329-D331 VanDerWaalsContact C-N 3.27Å; G329-D331 PolarHBondContact O-N 3Å; G329-D331 VanDerWaalsContact O-N 3.13Å; D331-I335 WeakPolarHBondContact O-CG1 3.15Å; D331-I335 PolarHBondContact O-N 2.8Å; D331-I335 VanDerWaalsContact O-N 3.1Å; D331-A496 HydrophobicContact CB-CB 4.21Å; D331-F552 HydrophobicContact CB-CE2 4.23Å; D331-K581 IonicContact OD1-NZ 3.96Å; D331-K581 PolarHBondContact OD1-NZ 2.7Å; D331-K581 IonicContact OD2-NZ 2.67Å; D331-K581 PolarHBondContact OD2-NZ 3.39Å; D331-L584 WeakPolarHBondContact OD1-CD2 3.25Å
332S98.4Very high98.1Very high6 Ų614.7 Ų14.74%0.0428%0.075CC..Hα-helixtrans-71.1-31.1179.161.40000112.9S327 G328 G329 I330 A336S327-S332 PolarHBondContact N-OG 3.37Å; G328-S332 PolarHBondContact N-OG 2.8Å; G329-S332 PolarHBondContact O-N 3.37Å; G329-S332 VanDerWaalsContact O-N 3.11Å; G329-S332 PolarHBondContact O-OG 3.42Å; I330-S332 PolarHBondContact O-N 3.44Å; S332-A336 VanDerWaalsContact O-CB 3.27Å; S332-A336 WeakPolarHBondContact O-CB 3.35Å; S332-A336 PolarHBondContact O-N 3.04Å
333M98.6Very high98Very high0 Ų014.9 Ų14.90%08%0.076CC..Hα-helixtrans-69.8-44.3177.5-70.8-67.3-59.200112F326 G329 I330 A336 T337 G412 E415 L416 L593F326-M333 HydrophobicContact CE2-CG 4.35Å; F326-M333 HydrophobicContact CE2-SD 3.49Å; F326-M333 WeakPolarHBondContact CE2-SD 3.36Å; F326-M333 HydrophobicContact CZ-SD 3.37Å; F326-M333 WeakPolarHBondContact CZ-SD 3.46Å; G329-M333 WeakPolarHBondContact O-CG 3.43Å; G329-M333 PolarHBondContact O-N 2.85Å; I330-M333 PolarHBondContact O-N 2.84Å; M333-A336 PolarHBondContact O-N 3.12Å; M333-T337 WeakPolarHBondContact O-CB 3.29Å; M333-T337 PolarHBondContact O-N 2.86Å; M333-T337 PolarHBondContact O-OG1 3.18Å; M333-G412 WeakPolarHBondContact CE-O 3.4Å; M333-G412 VanDerWaalsContact SD-CA 3.54Å; M333-E415 HydrophobicContact CE-CB 4.1Å; M333-E415 HydrophobicContact CE-CG 4.09Å; M333-E415 WeakPolarHBondContact CE-OE2 3.46Å; M333-L416 HydrophobicContact CE-CD2 3.94Å; M333-L416 HydrophobicContact CE-CG 3.75Å; M333-L416 HydrophobicContact SD-CD1 4.3Å; M333-L416 HydrophobicContact SD-CG 4.17Å; M333-L593 HydrophobicContact CB-CD1 3.91Å; M333-L593 HydrophobicContact CE-CD2 3.69Å
334V98.8Very high97.8Very high1 Ų117.2 Ų17.21%0.0069%0.091CC..Hα-helixtrans-65.8-44175.7169.90000110.6L290 I330 A336 T337 L338 L584 A588 L591 L593L290-V334 HydrophobicContact CD2-CG1 3.8Å; I330-V334 HydrophobicContact CG1-CG2 4.18Å; I330-V334 WeakPolarHBondContact O-CG2 3.12Å; I330-V334 PolarHBondContact O-N 3.49Å; V334-A336 PolarHBondContact O-N 2.84Å; V334-T337 PolarHBondContact O-N 2.99Å; V334-L338 HydrophobicContact CG1-CD1 3.95Å; V334-L338 HydrophobicContact CG1-CG 4.42Å; V334-L338 WeakPolarHBondContact O-CB 3.42Å; V334-L338 WeakPolarHBondContact O-CG 3.27Å; V334-L338 PolarHBondContact O-N 3.22Å; V334-L584 HydrophobicContact CB-CD1 3.97Å; V334-L584 HydrophobicContact CG1-CD1 3.84Å; V334-L584 HydrophobicContact CG2-CD1 3.76Å; V334-L584 HydrophobicContact CG2-CG 4.38Å; V334-A588 HydrophobicContact CG2-CB 3.75Å; V334-L591 HydrophobicContact CB-CD1 4.46Å; V334-L591 HydrophobicContact CG1-CD1 3.8Å; V334-L591 HydrophobicContact CG2-CD1 4.29Å; V334-L593 HydrophobicContact CG2-CD1 4.05Å
335I98.8Very high97.5Very high0 Ų022.5 Ų22.50%012%0.119CC..Hα-helixtrans-59.6-45.4174.6-72.5175.2000111.2I324 D331 L338 A339 L491 T492 P551 F552I324-I335 HydrophobicContact CD1-CG2 4.26Å; I324-I335 HydrophobicContact CG2-CG2 4.26Å; D331-I335 WeakPolarHBondContact O-CG1 3.15Å; D331-I335 PolarHBondContact O-N 2.8Å; D331-I335 VanDerWaalsContact O-N 3.1Å; I335-L338 PolarHBondContact O-N 2.95Å; I335-A339 VanDerWaalsContact O-CB 3.24Å; I335-A339 WeakPolarHBondContact O-CB 3.34Å; I335-A339 PolarHBondContact O-N 3.49Å; I335-L491 HydrophobicContact CG2-CB 3.78Å; I335-L491 HydrophobicContact CG2-CD1 3.72Å; I335-L491 HydrophobicContact CG2-CG 4.41Å; I335-T492 WeakPolarHBondContact CD1-O 3.32Å; I335-P551 HydrophobicContact CD1-CG 4.14Å; I335-P551 HydrophobicContact CG1-CG 4.37Å; I335-F552 HydrophobicContact CD1-CD2 3.94Å; I335-F552 HydrophobicContact CD1-CE2 3.62Å; I335-F552 HydrophobicContact CG1-CD2 4.49Å; I335-F552 HydrophobicContact CG1-CE2 3.84Å
336A98.8Very high97.1Very high0 Ų024.9 Ų24.90%013%0.132CC..Hα-helixtrans-60.7-48.1178.300000111.7I324 F326 S332 M333 V334 L338 A339 D340 L351 L416 W425I324-A336 VanDerWaalsContact CD1-CA 3.41Å; I324-A336 HydrophobicContact CD1-CB 3.67Å; F326-A336 HydrophobicContact CE2-CB 4.36Å; S332-A336 VanDerWaalsContact O-CB 3.27Å; S332-A336 WeakPolarHBondContact O-CB 3.35Å; S332-A336 PolarHBondContact O-N 3.04Å; M333-A336 PolarHBondContact O-N 3.12Å; V334-A336 PolarHBondContact O-N 2.84Å; A336-L338 VanDerWaalsContact C-N 3.31Å; A336-L338 PolarHBondContact O-N 3.45Å; A336-A339 PolarHBondContact O-N 3.03Å; A336-D340 PolarHBondContact O-N 2.83Å; A336-L351 HydrophobicContact CB-CD2 4.39Å; A336-L416 HydrophobicContact CB-CD1 3.81Å; A336-L416 HydrophobicContact CB-CD2 3.95Å; A336-W425 HydrophobicContact CB-CH2 4.1Å; A336-W425 HydrophobicContact CB-CZ3 4.02Å; A336-W425 WeakPolarHBondContact O-CH2 3.27Å
337T98.6Very high96.8Very high6 Ų625 Ų254%0.03713%0.133CC..Hα-helixtrans-60.9-39.8179.1-52.80000112M333 V334 V419 L591M333-T337 WeakPolarHBondContact O-CB 3.29Å; M333-T337 PolarHBondContact O-N 2.86Å; M333-T337 PolarHBondContact O-OG1 3.18Å; V334-T337 PolarHBondContact O-N 2.99Å; T337-V419 HydrophobicContact CG2-CG1 4.24Å; T337-L591 HydrophobicContact CG2-CB 4.14Å
338L98.7Very high96.8Very high0 Ų023.8 Ų23.80%012%0.123CC..Hα-helixtrans-74.8-34.7176.4-68.6177.6000112.7I287 L290 V294 V334 I335 A336 D340 R341 H342 L591I287-L338 HydrophobicContact CG2-CD2 4.45Å; L290-L338 HydrophobicContact CB-CD1 4.1Å; L290-L338 HydrophobicContact CD2-CD1 3.76Å; L290-L338 HydrophobicContact CG-CD1 3.63Å; V294-L338 HydrophobicContact CB-CB 4.27Å; V294-L338 HydrophobicContact CG1-CB 4.26Å; V294-L338 HydrophobicContact CG2-CB 4.05Å; V294-L338 HydrophobicContact CG2-CD1 4.39Å; V334-L338 HydrophobicContact CG1-CD1 3.95Å; V334-L338 HydrophobicContact CG1-CG 4.42Å; V334-L338 WeakPolarHBondContact O-CB 3.42Å; V334-L338 WeakPolarHBondContact O-CG 3.27Å; V334-L338 PolarHBondContact O-N 3.22Å; I335-L338 PolarHBondContact O-N 2.95Å; A336-L338 VanDerWaalsContact C-N 3.31Å; A336-L338 PolarHBondContact O-N 3.45Å; L338-D340 VanDerWaalsContact C-N 3.32Å; L338-D340 PolarHBondContact O-N 3.04Å; L338-R341 WeakPolarHBondContact O-CB 3.17Å; L338-R341 PolarHBondContact O-N 2.69Å; L338-H342 PolarHBondContact O-CD2 2.97Å; L338-L591 HydrophobicContact CD2-CD1 4.21Å; L338-L591 HydrophobicContact CD2-CD2 3.89Å; L338-L591 HydrophobicContact CG-CD1 4.23Å
339A98.5Very high96.8Very high0 Ų023.8 Ų23.80%012%0.123CC..Hα-helixtrans-64.3-39.4177.500000111.3V294 I324 I335 A336 R341 H342 I343 L491V294-A339 HydrophobicContact CG1-CB 4Å; I324-A339 HydrophobicContact CD1-CB 4.26Å; I335-A339 VanDerWaalsContact O-CB 3.24Å; I335-A339 WeakPolarHBondContact O-CB 3.34Å; I335-A339 PolarHBondContact O-N 3.49Å; A336-A339 PolarHBondContact O-N 3.03Å; A339-R341 PolarHBondContact O-N 2.95Å; A339-H342 PolarHBondContact O-N 3.39Å; A339-H342 VanDerWaalsContact O-N 3.08Å; A339-I343 HydrophobicContact CB-CD1 4.07Å; A339-I343 WeakPolarHBondContact O-CG1 3.25Å; A339-I343 PolarHBondContact O-N 2.86Å; A339-L491 HydrophobicContact CB-CD1 3.98Å
340D98Very high96.9Very high22 Ų2222.9 Ų22.912%0.11811%0.114CC..Hα-helixtrans-54.1-36.6174.217847.7000113.3A336 L338 H342 I349 S420 R423 W425A336-D340 PolarHBondContact O-N 2.83Å; L338-D340 VanDerWaalsContact C-N 3.32Å; L338-D340 PolarHBondContact O-N 3.04Å; D340-H342 PolarHBondContact O-N 2.88Å; D340-I349 HydrophobicContact CB-CD1 4.42Å; D340-S420 VanDerWaalsContact CG-OG 3.28Å; D340-S420 PolarHBondContact OD1-OG 2.78Å; D340-S420 WeakPolarHBondContact OD2-CB 3.15Å; D340-S420 PolarHBondContact OD2-OG 2.89Å; D340-R423 PolarHBondContact O-NH2 2.75Å; D340-R423 IonicContact OD1-CZ 3.77Å; D340-R423 IonicContact OD1-NE 2.56Å; D340-R423 PolarHBondContact OD1-NE 3.45Å; D340-R423 IonicContact OD1-NH2 3.08Å; D340-R423 PolarHBondContact OD1-NH2 3Å; D340-W425 HydrophobicContact CB-CH2 3.91Å; D340-W425 HydrophobicContact CB-CZ2 3.99Å
341R96.8Very high96.9Very high128 Ų12822.5 Ų22.548%0.48311%0.112SC..THydrogen-bonded Turntrans-64.9-24.4179.6-63.4179.7176.2-171.7-9.6113.9L338 A339 L591L338-R341 WeakPolarHBondContact O-CB 3.17Å; L338-R341 PolarHBondContact O-N 2.69Å; A339-R341 PolarHBondContact O-N 2.95Å; R341-L591 VanDerWaalsContact CZ-CD2 3.43Å
342H97.4Very high97Very high38 Ų3821.5 Ų21.518%0.17611%0.107CC..THydrogen-bonded Turntrans-117.8-17.9-169.1-58.1-62.9000113.6S291 K295 V298 L338 A339 D340S291-H342 PolarHBondContact O-NE2 2.8Å; S291-H342 VanDerWaalsContact O-NE2 3.16Å; S291-H342 PolarHBondContact OG-CE1 3.31Å; S291-H342 PolarHBondContact OG-NE2 3.16Å; K295-H342 HydrophobicContact CB-CB 4.32Å; K295-H342 HydrophobicContact CG-CB 4.34Å; V298-H342 HydrophobicContact CG2-CB 3.7Å; L338-H342 PolarHBondContact O-CD2 2.97Å; A339-H342 PolarHBondContact O-N 3.39Å; A339-H342 VanDerWaalsContact O-N 3.08Å; D340-H342 PolarHBondContact O-N 2.88Å
343I96.3Very high97Very high5 Ų521.3 Ų21.33%0.02611%0.105CC..SBendtrans-84134.2175.1-67.8172000108.8V298 V322 A339 L345 E347 I349 R423V298-I343 HydrophobicContact CB-CD1 4.38Å; V298-I343 HydrophobicContact CB-CG1 3.94Å; V298-I343 HydrophobicContact CG1-CD1 4.24Å; V298-I343 HydrophobicContact CG1-CG1 4.3Å; V298-I343 HydrophobicContact CG2-CG1 3.98Å; V322-I343 HydrophobicContact CB-CD1 3.77Å; V322-I343 HydrophobicContact CG1-CD1 4Å; V322-I343 HydrophobicContact CG2-CD1 3.91Å; V322-I343 HydrophobicContact CG2-CG1 4.5Å; A339-I343 HydrophobicContact CB-CD1 4.07Å; A339-I343 WeakPolarHBondContact O-CG1 3.25Å; A339-I343 PolarHBondContact O-N 2.86Å; I343-L345 PolarHBondContact O-N 2.79Å; I343-E347 HydrophobicContact CG2-CB 3.86Å; I343-E347 HydrophobicContact CG2-CG 4.11Å; I343-I349 HydrophobicContact CB-CD1 4.44Å; I343-I349 HydrophobicContact CD1-CD1 3.76Å; I343-I349 HydrophobicContact CD1-CG1 3.76Å; I343-I349 HydrophobicContact CG2-CG1 4.34Å; I343-R423 PolarHBondContact O-NH2 3.26Å
344P93.9Very high96.9Very high49 Ų4921.7 Ų21.732%0.31811%0.108SC..  trans-48.7131.1176.7-28.836.3000111.9D346 E347 R423P344-D346 WeakPolarHBondContact CB-OD1 3.39Å; P344-D346 PolarHBondContact O-N 3.05Å; P344-E347 HydrophobicContact CB-CB 4.42Å; P344-E347 WeakPolarHBondContact O-CB 3.15Å; P344-E347 PolarHBondContact O-N 2.9Å; P344-R423 PolarHBondContact O-NH1 3.13Å
345L91.5Very high96.8Very high112 Ų11221.7 Ų21.759%0.58611%0.108SC*.THydrogen-bonded Turntrans-54.7-27.5-169.8-74171.7000114.5I343 R423I343-L345 PolarHBondContact O-N 2.79Å; L345-R423 PolarHBondContact O-NH1 3.19Å
346D89.7Confident96.6Very high67 Ų6721.9 Ų21.936%0.35811%0.108SC..THydrogen-bonded Turntrans-88.2-5.3-17763.4-29.5000114.3R318 P344R318-D346 VanDerWaalsContact CD-O 3.28Å; R318-D346 WeakPolarHBondContact CD-O 3.45Å; R318-D346 IonicContact CZ-OD2 3.37Å; R318-D346 IonicContact NE-OD2 3.62Å; R318-D346 IonicContact NH1-OD2 3.77Å; R318-D346 PolarHBondContact NH1-OD2 3.43Å; R318-D346 IonicContact NH2-OD2 3.45Å; R318-D346 PolarHBondContact NH2-OD2 2.78Å; P344-D346 WeakPolarHBondContact CB-OD1 3.39Å; P344-D346 PolarHBondContact O-N 3.05Å
347E93.5Very high96.1Very high9 Ų924.1 Ų24.14%0.04212%0.12CC..SBendtrans-93.8123.3175-173.2-175.7157.500110.5R303 N321 I343 P344 R423R303-E347 IonicContact CZ-OE2 3.72Å; R303-E347 IonicContact NE-OE2 2.6Å; R303-E347 PolarHBondContact NE-OE2 3.19Å; R303-E347 IonicContact NH2-OE2 2.97Å; N321-E347 WeakPolarHBondContact CB-OE1 3.49Å; N321-E347 PolarHBondContact N-OE1 3.42Å; N321-E347 PolarHBondContact ND2-OE1 3.34Å; I343-E347 HydrophobicContact CG2-CB 3.86Å; I343-E347 HydrophobicContact CG2-CG 4.11Å; P344-E347 HydrophobicContact CB-CB 4.42Å; P344-E347 WeakPolarHBondContact O-CB 3.15Å; P344-E347 PolarHBondContact O-N 2.9Å; E347-R423 PolarHBondContact O-NH1 3.49Å
348P96Very high95Very high6 Ų627.2 Ų27.24%0.03915%0.146CC..  trans-65154.1174.9-23.335.3000113.2R318 A320 I424 N426R318-P348 WeakPolarHBondContact O-CG 3.24Å; A320-P348 WeakPolarHBondContact CA-O 3.5Å; A320-P348 HydrophobicContact CB-CB 4.39Å; A320-P348 WeakPolarHBondContact CB-O 3.49Å; P348-I424 WeakPolarHBondContact CA-O 3.26Å; P348-I424 HydrophobicContact CB-CB 4.01Å; P348-I424 HydrophobicContact CB-CG2 3.86Å; P348-I424 HydrophobicContact CG-CB 4.09Å; P348-I424 HydrophobicContact CG-CD1 4.27Å; P348-I424 HydrophobicContact CG-CG2 3.98Å; P348-N426 VanDerWaalsContact CB-ND2 3.34Å; P348-N426 WeakPolarHBondContact CB-ND2 3.36Å
349I98.1Very high93.2Very high0 Ų033.3 Ų33.30%018%0.175CC..EExtended strand (participates in β ladder)trans-112.2124.3169.6-60.3170000109I324 D340 I343 L351 R423 I424 W425 N426I324-I349 HydrophobicContact CD1-CG2 3.86Å; I324-I349 HydrophobicContact CG1-CG2 4.1Å; D340-I349 HydrophobicContact CB-CD1 4.42Å; I343-I349 HydrophobicContact CB-CD1 4.44Å; I343-I349 HydrophobicContact CD1-CD1 3.76Å; I343-I349 HydrophobicContact CD1-CG1 3.76Å; I343-I349 HydrophobicContact CG2-CG1 4.34Å; I349-L351 HydrophobicContact CG2-CD2 4.28Å; I349-R423 HydrophobicContact CD1-CG 4.4Å; I349-I424 PolarHBondContact N-O 2.96Å; I349-W425 HydrophobicContact CB-CE3 3.87Å; I349-W425 HydrophobicContact CB-CZ3 3.76Å; I349-W425 HydrophobicContact CD1-CE3 4.43Å; I349-W425 HydrophobicContact CD1-CH2 3.83Å; I349-W425 HydrophobicContact CD1-CZ3 3.66Å; I349-W425 HydrophobicContact CG1-CZ3 4.29Å; I349-W425 HydrophobicContact CG2-CE3 4.13Å; I349-W425 HydrophobicContact CG2-CZ3 3.76Å; I349-N426 PolarHBondContact O-N 3.38Å
350D98.6Very high90.9Very high0 Ų042.1 Ų42.10%022%0.216CC..EExtended strand (participates in β ladder)trans-83.8123.7177.3-74.2-6.2000110.9A320 V322 A323 I324 L352 N426 V428 Y483 S485A320-D350 HydrophobicContact CB-CB 4.2Å; A320-D350 VanDerWaalsContact CB-CG 3.42Å; A320-D350 WeakPolarHBondContact CB-OD1 3.39Å; V322-D350 PolarHBondContact O-N 2.81Å; A323-D350 CarbonylContact C-O 3.5Å; A323-D350 WeakPolarHBondContact CA-O 3.31Å; A323-D350 HydrophobicContact CB-CB 3.84Å; I324-D350 PolarHBondContact N-O 3.02Å; D350-L352 HydrophobicContact CB-CD2 4.19Å; D350-N426 WeakPolarHBondContact OD1-CB 3.21Å; D350-N426 PolarHBondContact OD1-ND2 2.93Å; D350-V428 HydrophobicContact CB-CG2 4.49Å; D350-Y483 PolarHBondContact OD1-OH 2.76Å; D350-Y483 WeakPolarHBondContact OD2-CE1 3.47Å; D350-Y483 PolarHBondContact OD2-OH 3.09Å; D350-S485 WeakPolarHBondContact OD2-CA 3.22Å; D350-S485 WeakPolarHBondContact OD2-CB 3.35Å; D350-S485 PolarHBondContact OD2-OG 3.4Å
351L98.8Very high88Confident0 Ų050.1 Ų50.10%025%0.249CC..EExtended strand (participates in β ladder)trans-103.7104.8174.3-55.7179.8000108.6I324 F326 A336 I349 L413 L416 W425 N426 F427 V428I324-L351 HydrophobicContact CB-CD2 4.17Å; I324-L351 HydrophobicContact CD1-CD2 4.14Å; I324-L351 HydrophobicContact CG1-CD2 4.47Å; F326-L351 HydrophobicContact CB-CB 3.88Å; F326-L351 HydrophobicContact CB-CD2 4.31Å; F326-L351 HydrophobicContact CD1-CB 3.92Å; F326-L351 HydrophobicContact CD1-CD1 4.15Å; F326-L351 HydrophobicContact CD1-CG 4.47Å; F326-L351 HydrophobicContact CD2-CD1 4.39Å; F326-L351 HydrophobicContact CD2-CD2 3.84Å; F326-L351 HydrophobicContact CD2-CG 4.48Å; F326-L351 HydrophobicContact CE1-CD1 4.01Å; F326-L351 HydrophobicContact CE2-CD1 4.27Å; F326-L351 HydrophobicContact CE2-CD2 4.29Å; F326-L351 HydrophobicContact CG-CB 3.86Å; F326-L351 HydrophobicContact CG-CD1 4.32Å; F326-L351 HydrophobicContact CG-CD2 4.03Å; F326-L351 HydrophobicContact CG-CG 4.29Å; F326-L351 HydrophobicContact CZ-CD1 4.06Å; A336-L351 HydrophobicContact CB-CD2 4.39Å; I349-L351 HydrophobicContact CG2-CD2 4.28Å; L351-L413 HydrophobicContact CD1-CD1 4.03Å; L351-L416 HydrophobicContact CD1-CD1 3.76Å; L351-W425 HydrophobicContact CD1-CB 4.34Å; L351-W425 HydrophobicContact CD1-CD2 4.49Å; L351-W425 HydrophobicContact CD1-CE3 3.95Å; L351-W425 HydrophobicContact CD2-CE3 3.92Å; L351-W425 HydrophobicContact CD2-CZ3 4.05Å; L351-W425 HydrophobicContact CG-CE3 4.04Å; L351-N426 PolarHBondContact N-O 2.77Å; L351-F427 HydrophobicContact CB-CD2 4Å; L351-F427 HydrophobicContact CD1-CD2 4.42Å; L351-V428 PolarHBondContact O-N 3.12Å
352L98.8Very high84.7Confident2 Ų250.6 Ų50.61%0.0127%0.267CS..EExtended strand (participates in β ladder)trans-89.8110.4-173.9-51.7-177.9000110.1A323 I324 L325 F326 D350 V428 I430 A467A323-L352 HydrophobicContact CB-CD1 3.76Å; A323-L352 HydrophobicContact CB-CD2 4.41Å; A323-L352 HydrophobicContact CB-CG 3.97Å; I324-L352 PolarHBondContact O-N 3.37Å; L325-L352 HydrophobicContact CD2-CB 4.36Å; L325-L352 HydrophobicContact CD2-CD1 4.4Å; F326-L352 PolarHBondContact N-O 2.94Å; D350-L352 HydrophobicContact CB-CD2 4.19Å; L352-V428 HydrophobicContact CD2-CB 3.94Å; L352-V428 HydrophobicContact CD2-CG1 4.47Å; L352-V428 HydrophobicContact CD2-CG2 3.85Å; L352-I430 HydrophobicContact CB-CD1 4.19Å; L352-A467 WeakPolarHBondContact CD1-O 3.44Å
353N98.1Very high81.4Confident2 Ų256.4 Ų56.41%0.01130%0.296CS..EExtended strand (participates in β ladder)trans-123.2117.7-177.6-176.3-85.5000111.3F326 D405 R406 F427 V428 I430F326-N353 WeakPolarHBondContact O-CB 3.32Å; F326-N353 PolarHBondContact O-ND2 3.2Å; N353-D405 PolarHBondContact ND2-O 2.59Å; N353-R406 PolarHBondContact O-NH1 3.32Å; N353-R406 PolarHBondContact O-NH2 2.97Å; N353-R406 WeakPolarHBondContact OD1-CA 3.4Å; N353-R406 PolarHBondContact OD1-NH1 3.43Å; N353-F427 HydrophobicContact CB-CD2 4.48Å; N353-F427 HydrophobicContact CB-CE2 3.59Å; N353-F427 HydrophobicContact CB-CZ 3.65Å; N353-V428 PolarHBondContact N-O 3.01Å; N353-V428 VanDerWaalsContact N-O 3.13Å; N353-I430 PolarHBondContact O-N 3.18Å
354V97.4Very high78.3Confident9 Ų961.3 Ų61.36%0.05533%0.328CS..EExtended strand (participates in β ladder)trans-100.5137.3-175.668.10000112.6F356 I430 V432 A463 F466 A467V354-F356 HydrophobicContact CG1-CE2 4.43Å; V354-F356 HydrophobicContact CG2-CD2 4.4Å; V354-F356 HydrophobicContact CG2-CE2 3.79Å; V354-F356 HydrophobicContact CG2-CZ 4.18Å; V354-I430 CarbonylContact C-O 3.6Å; V354-I430 WeakPolarHBondContact CA-O 3.33Å; V354-I430 HydrophobicContact CB-CB 4.43Å; V354-I430 HydrophobicContact CG2-CB 4.48Å; V354-I430 HydrophobicContact CG2-CG2 4.14Å; V354-V432 HydrophobicContact CG2-CG2 3.97Å; V354-A463 HydrophobicContact CG1-CB 4.49Å; V354-F466 HydrophobicContact CG2-CB 3.9Å; V354-A467 HydrophobicContact CB-CB 3.95Å; V354-A467 HydrophobicContact CG1-CB 3.93Å
355A96.4Very high75.3Confident0 Ų065.8 Ų65.80%036%0.355CS..EExtended strand (participates in β ladder)trans-134.7134.4175.900000110.5V401 V403 I430 N431 V432A355-V401 HydrophobicContact CB-CG1 3.92Å; A355-V403 HydrophobicContact CB-CB 4.45Å; A355-V403 HydrophobicContact CB-CG1 4.22Å; A355-V403 HydrophobicContact CB-CG2 3.39Å; A355-I430 PolarHBondContact N-O 3.45Å; A355-N431 WeakPolarHBondContact O-CA 3.38Å; A355-V432 PolarHBondContact O-N 3.33Å
356F94.3Very high72.3Confident4 Ų465.5 Ų65.52%0.01836%0.363CS..EExtended strand (participates in β ladder)trans-102115175.9-70.2-91.6000109.1V354 V432 L437 A463 F466 S608 I610 M613V354-F356 HydrophobicContact CG1-CE2 4.43Å; V354-F356 HydrophobicContact CG2-CD2 4.4Å; V354-F356 HydrophobicContact CG2-CE2 3.79Å; V354-F356 HydrophobicContact CG2-CZ 4.18Å; F356-V432 WeakPolarHBondContact CA-O 3.43Å; F356-V432 HydrophobicContact CD1-CB 3.8Å; F356-V432 HydrophobicContact CD1-CG1 3.88Å; F356-V432 HydrophobicContact CE1-CB 3.85Å; F356-V432 HydrophobicContact CE1-CG1 3.71Å; F356-V432 HydrophobicContact CE1-CG2 4.2Å; F356-V432 HydrophobicContact CG-CB 4.46Å; F356-V432 HydrophobicContact CZ-CG2 4.47Å; F356-L437 HydrophobicContact CD1-CD2 4.19Å; F356-L437 HydrophobicContact CE1-CB 4.44Å; F356-L437 HydrophobicContact CE1-CD1 4.05Å; F356-L437 HydrophobicContact CE1-CD2 4.2Å; F356-L437 HydrophobicContact CE1-CG 4.44Å; F356-A463 HydrophobicContact CE2-CB 4.01Å; F356-A463 HydrophobicContact CZ-CB 4.4Å; F356-F466 AromaticContact CE1-CD2 3.96Å; F356-F466 HydrophobicContact CE1-CD2 3.96Å; F356-F466 HydrophobicContact CE1-CE2 4.31Å; F356-F466 HydrophobicContact CZ-CB 4.47Å; F356-F466 AromaticContact CZ-CD2 3.95Å; F356-F466 HydrophobicContact CZ-CD2 3.95Å; F356-F466 HydrophobicContact CZ-CG 4.5Å; F356-S608 WeakPolarHBondContact CB-O 3.09Å; F356-S608 WeakPolarHBondContact CD2-OG 3.45Å; F356-S608 PolarHBondContact N-O 3.48Å; F356-I610 HydrophobicContact CB-CB 4.44Å; F356-I610 HydrophobicContact CD1-CB 4.2Å; F356-I610 HydrophobicContact CD1-CD1 4.33Å; F356-I610 HydrophobicContact CD1-CG1 4.22Å; F356-I610 HydrophobicContact CD2-CB 3.6Å; F356-I610 HydrophobicContact CD2-CG1 4.43Å; F356-I610 HydrophobicContact CD2-CG2 4.46Å; F356-I610 HydrophobicContact CE1-CB 4.39Å; F356-I610 HydrophobicContact CE1-CD1 3.82Å; F356-I610 HydrophobicContact CE1-CG1 4.21Å; F356-I610 HydrophobicContact CE2-CB 3.81Å; F356-I610 HydrophobicContact CE2-CD1 4.15Å; F356-I610 HydrophobicContact CE2-CG1 4.41Å; F356-I610 HydrophobicContact CE2-CG2 4.42Å; F356-I610 HydrophobicContact CG-CB 3.81Å; F356-I610 HydrophobicContact CG-CG1 4.33Å; F356-I610 HydrophobicContact CZ-CB 4.21Å; F356-I610 HydrophobicContact CZ-CD1 3.71Å; F356-I610 HydrophobicContact CZ-CG1 4.3Å; F356-M613 HydrophobicContact CB-CE 4.28Å; F356-M613 HydrophobicContact CB-SD 3.65Å; F356-M613 HydrophobicContact CD1-CE 3.81Å; F356-M613 HydrophobicContact CD1-SD 4.23Å; F356-M613 HydrophobicContact CG-CE 4.48Å; F356-M613 HydrophobicContact CG-SD 4.43Å
357I88.3Confident69.3Low48 Ų4872.2 Ų72.225%0.24639%0.389CS..EExtended strand (participates in β ladder)trans-103.8124.7-170.8-52.6175.3000108.6V401 N431 V432I357-V401 HydrophobicContact CD1-CB 4.34Å; I357-V401 HydrophobicContact CD1-CG1 3.79Å; I357-V401 HydrophobicContact CD1-CG2 3.65Å; I357-V401 HydrophobicContact CG1-CG1 4.07Å; I357-N431 HydrophobicContact CD1-CB 3.62Å; I357-V432 PolarHBondContact N-O 3.32Å
358A75.9Confident66.2Low71 Ų7179.4 Ų79.459%0.58743%0.427SS*.PPolyproline II helixtrans-82.2126.1168.900000108.8
359E60.9Low62.9Low128 Ų12889 Ų8960%0.59847%0.469SS*.PPolyproline II helixtrans-71.7133.7169.4-68.8176.8-171.300109.5
360E49.8Very low59.5Low185 Ų18598 Ų9886%0.86451%0.511SS*.PPolyproline II helixtrans-76.3133.3166.8-78.1-172.7168.700109.4T362E360-T362 PolarHBondContact O-N 2.78Å
361K37.4Very low56.1Low189 Ų189110 Ų11082%0.82256%0.556SS**  trans-59.8110.2162.3-70179.9178.4-178.40107.1M363K361-M363 VanDerWaalsContact C-N 3.3Å; K361-M363 PolarHBondContact O-N 3.29Å
362T27.8Very low52.6Low139 Ų139117.6 Ų117.685%0.85360%0.596SS**  trans-56.699.2160.342.30000107.5E360E360-T362 PolarHBondContact O-N 2.78Å
363M28.8Very low49.2Very low159 Ų159126.5 Ų126.578%0.78364%0.635SS**  trans-67.8126.8169.1-72.9-70.1-81.900107K361 T365K361-M363 VanDerWaalsContact C-N 3.3Å; K361-M363 PolarHBondContact O-N 3.29Å; M363-T365 PolarHBondContact O-N 3.01Å
364P31.2Very low45.8Very low109 Ų109134.1 Ų134.171%0.70867%0.671SS**  trans-62.1129.9171-13.426.8000108.3S366P364-S366 PolarHBondContact O-N 3.43Å
365T31.1Very low42.3Very low142 Ų142142.6 Ų142.687%0.87171%0.707SS**  trans-53.6105.4167.140.90000109.7M363M363-T365 PolarHBondContact O-N 3.01Å
366S27.3Very low38.9Very low107 Ų107149.7 Ų149.775%0.74875%0.745SS**  trans-115.9106.8168.365.30000110.2P364P364-S366 PolarHBondContact O-N 3.43Å
367F26.9Very low35.5Very low207 Ų207159.1 Ų159.191%0.90879%0.786SS**  trans5.2131.6153.2-69.5-89.7000119.7
368N28Very low32.3Very low160 Ų160162 Ų16286%0.85681%0.809SS**  trans-34.3135.3163.3-74.2-23.1000115.2
369K27.7Very low29.8Very low209 Ų209166.7 Ų166.791%0.90982%0.819SS**  trans-155.7114.5134.1-110.1170.8-172.9176.40110.4
370E27.2Very low28Very low188 Ų188168.4 Ų168.488%0.87983%0.83SS**  trans-58.9146.7167.3-63.7179.5143.300111.6
371R25.8Very low26.7Very low253 Ų253165 Ų16596%0.95583%0.827SS**  trans-164.3121.8137.8-107.1168-171.5-163.61.9111.9
372N25.5Very low26.1Very low158 Ų158161.7 Ų161.785%0.84583%0.828SS**  trans-65.1141.9171-83-37.2000113.2
373K27.5Very low26.1Very low189 Ų189163 Ų16382%0.82282%0.824SS**  167.7125.7112.8-94.9179.9177.8178.60114.8
374Q26.3Very low25.9Very low163 Ų163163 Ų16376%0.76282%0.822SS**  trans58.1115.2134.5-82.2169.4-2000124
375K24.8Very low25.6Very low186 Ų186168 Ų16881%0.80983%0.833SS**  50.5119128-79.9-176.7173.7178.40120.6
376N23.8Very low25.6Very low149 Ų149166.6 Ų166.680%0.79783%0.829SS**  -176.4132.4104.8-92.6-22000113.1
377K24.7Very low25.6Very low202 Ų202169.8 Ų169.888%0.87883%0.83SS**  trans32.5144.2143.9-87.2-179.2175.1-176.50120.3
378C21Very low25.5Very low109 Ų109168 Ų16874%0.73683%0.829SS**  cis-170.916910.7-152.80000108.6
379E21.8Very low25.5Very low169 Ų169167.2 Ų167.279%0.7983%0.825SS**  trans104.691.8155.4-67.4176.5-170.200121.3
380I23.6Very low25.5Very low165 Ų165162.2 Ų162.285%0.84682%0.823SS**  trans53.499.8133.7-47.7170000117.7
381S22.8Very low25.6Very low112 Ų112158.3 Ų158.378%0.78382%0.823SS**  trans-118.7138.7164.2590000111.1
382S25.5Very low25.7Very low121 Ų121151 Ų15185%0.84682%0.816SS**  trans-64.1119.1176.341.50000113.9
383E27.2Very low26Very low165 Ų165151.5 Ų151.577%0.77182%0.819SS**  trans-60.7153.1152.7-70.5168.6-179.100109.5
384E24.9Very low26.2Very low161 Ų161149.6 Ų149.675%0.75282%0.818SS**  cis-170.2143.61.7-110170.8179.100105.5
385F25.4Very low26.6Very low213 Ų213149.8 Ų149.893%0.93482%0.824SS**  trans-135.1116.8151.3-103.2-79.3000106.7
386S29.3Very low27Very low113 Ų113144.3 Ų144.379%0.7981%0.809SS**  trans-63.8137.9-171.839.20000112.9
387K27.6Very low27.7Very low174 Ų174142.8 Ų142.876%0.75781%0.808SS**  trans-77.9147.1156.4-72.3176.3171.9-177.40108.4
388D25Very low28.6Very low169 Ų169138.2 Ų138.290%0.90479%0.793SS**  trans-142.5136.6139.2-94.4-35.4000109.5
389D28.1Very low29.7Very low143 Ų143141.8 Ų141.877%0.76580%0.796SS**  trans-87.1156.8-164.2-74.4-49.6000113.6
390A27Very low31.2Very low104 Ų104141 Ų14186%0.8679%0.792SS**  trans-150.3112.213900000109.2
391A31Very low33.1Very low107 Ų107134.4 Ų134.488%0.88476%0.759SS**  trans-79.1135.1174.500000110.9
392A28.1Very low35.9Very low98 Ų98132.3 Ų132.381%0.8174%0.744SS**  trans-151.8132.8154.300000108.4
393D31.7Very low39Very low170 Ų170126.8 Ų126.891%0.90971%0.705SS**  trans-45.9130.5166.2-92.3-33.7000111
394D30.3Very low42.2Very low148 Ų148120.2 Ų120.279%0.79168%0.677SS**  -172.2132.8127.6-144.5-0.6000110.5S396D394-S396 PolarHBondContact O-N 2.97Å
395D34.4Very low45.6Very low167 Ų167113 Ų11389%0.89364%0.644SS**  trans-82.797.1-177.8-157.613.9000108.5
396S35Very low49Very low71 Ų71103 Ų10350%0.49760%0.6SS.*  trans-133148.6177700000113.1D394 D398D394-S396 PolarHBondContact O-N 2.97Å; S396-D398 PolarHBondContact O-N 3.11Å
397P37.9Very low52.1Low118 Ų118101.9 Ų101.977%0.76658%0.584SS**G310 helixtrans-71.5-0.3-171.6-12.528.4000114.9K399P397-K399 PolarHBondContact O-N 3.35Å
398D43.8Very low55.4Low105 Ų10594.6 Ų94.656%0.56155%0.554SS**G310 helixtrans-87.50-164-15914.4000114.4S396 H400 R410S396-D398 PolarHBondContact O-N 3.11Å; D398-H400 PolarHBondContact O-N 3.43Å; D398-R410 IonicContact OD1-CZ 3.26Å; D398-R410 IonicContact OD1-NH1 2.82Å; D398-R410 PolarHBondContact OD1-NH1 3.26Å; D398-R410 IonicContact OD1-NH2 2.93Å; D398-R410 IonicContact OD2-NH1 3.19Å
399K44Very low58.9Low184 Ų18486.6 Ų86.680%0.851%0.511SS*.G310 helixtrans-72.8-10.8174.8-90.1-179.6-179.9167.70114.3P397 V401P397-K399 PolarHBondContact O-N 3.35Å; K399-V401 PolarHBondContact O-N 2.97Å
400H52.6Low62.2Low154 Ų15482.9 Ų82.971%0.71349%0.487SS*.G310 helixtrans-80.1-8.1-164.3-78.9-78.2000116.6D398D398-H400 PolarHBondContact O-N 3.43Å
401V63.8Low65.5Low26 Ų2680.5 Ų80.516%0.15847%0.467CS..G310 helixtrans-135.956.9178.5-162.50000112.9A355 I357 K399 V403 R406A355-V401 HydrophobicContact CB-CG1 3.92Å; I357-V401 HydrophobicContact CD1-CB 4.34Å; I357-V401 HydrophobicContact CD1-CG1 3.79Å; I357-V401 HydrophobicContact CD1-CG2 3.65Å; I357-V401 HydrophobicContact CG1-CG1 4.07Å; K399-V401 PolarHBondContact O-N 2.97Å; V401-V403 PolarHBondContact O-N 2.96Å; V401-R406 WeakPolarHBondContact O-CG 3.32Å
402S80.6Confident68.7Low67 Ų6775.6 Ų75.647%0.46943%0.427SS..  trans-94.161.4-179.4-164.30000112.7I407 R609S402-I407 WeakPolarHBondContact OG-CD1 3.06Å; S402-R609 PolarHBondContact O-NH2 3.4Å; S402-R609 VanDerWaalsContact O-NH2 3.11Å
403V92.2Very high72Confident5 Ų572 Ų723%0.0339%0.394CS..  trans-86.6149170.2-51.50000110.8A355 V401 D405 R406 I407 R609A355-V403 HydrophobicContact CB-CB 4.45Å; A355-V403 HydrophobicContact CB-CG1 4.22Å; A355-V403 HydrophobicContact CB-CG2 3.39Å; V401-V403 PolarHBondContact O-N 2.96Å; V403-D405 VanDerWaalsContact C-N 3.34Å; V403-D405 PolarHBondContact O-N 3.21Å; V403-R406 HydrophobicContact CG2-CB 3.58Å; V403-R406 WeakPolarHBondContact O-CB 3.42Å; V403-R406 PolarHBondContact O-N 3.41Å; V403-I407 WeakPolarHBondContact O-CG1 3.25Å; V403-I407 PolarHBondContact O-N 2.94Å; V403-I407 VanDerWaalsContact O-N 3.09Å; V403-R609 HydrophobicContact CB-CG 4Å; V403-R609 HydrophobicContact CG1-CB 4.27Å; V403-R609 HydrophobicContact CG1-CG 3.96Å
404P94.6Very high75.2Confident27 Ų2771.5 Ų71.518%0.17538%0.384CS..Hα-helixtrans-56.7-40.3-171.5-22.528.5000115.2I407 T408 R602 G607P404-I407 PolarHBondContact O-N 3.26Å; P404-T408 PolarHBondContact O-N 2.67Å; P404-T408 VanDerWaalsContact O-N 3.09Å; P404-T408 PolarHBondContact O-OG1 3.47Å; P404-R602 VanDerWaalsContact CB-CZ 3.44Å; P404-G607 VanDerWaalsContact CD-O 3.27Å; P404-G607 WeakPolarHBondContact CD-O 3.44Å
405D95.8Very high78.4Confident11 Ų1165.3 Ų65.36%0.05935%0.35CS..Hα-helixtrans-74.9-23.9178.6-75.52.6000113.2N353 V403 T408 G409 G607N353-D405 PolarHBondContact ND2-O 2.59Å; V403-D405 VanDerWaalsContact C-N 3.34Å; V403-D405 PolarHBondContact O-N 3.21Å; D405-T408 WeakPolarHBondContact CA-OG1 3.41Å; D405-T408 PolarHBondContact O-OG1 2.9Å; D405-G409 WeakPolarHBondContact O-CA 3.31Å; D405-G409 PolarHBondContact O-N 2.98Å; D405-G607 PolarHBondContact N-O 3.35Å; D405-G607 WeakPolarHBondContact OD1-CA 3.35Å; D405-G607 WeakPolarHBondContact OD2-CA 3.44Å
406R95.7Very high81.4Confident1 Ų157.5 Ų57.50%0.00431%0.308CS..Hα-helixtrans-69.2-43.6171.41776969.4-147.8-8.2110.1N353 V401 V403 G409 R410 E429 I430 N431N353-R406 PolarHBondContact O-NH1 3.32Å; N353-R406 PolarHBondContact O-NH2 2.97Å; N353-R406 WeakPolarHBondContact OD1-CA 3.4Å; N353-R406 PolarHBondContact OD1-NH1 3.43Å; V401-R406 WeakPolarHBondContact O-CG 3.32Å; V403-R406 HydrophobicContact CG2-CB 3.58Å; V403-R406 WeakPolarHBondContact O-CB 3.42Å; V403-R406 PolarHBondContact O-N 3.41Å; R406-G409 PolarHBondContact O-N 3.38Å; R406-R410 WeakPolarHBondContact O-CB 3.39Å; R406-R410 WeakPolarHBondContact O-CG 3.25Å; R406-R410 PolarHBondContact O-N 2.66Å; R406-E429 WeakPolarHBondContact CD-OE1 3.37Å; R406-E429 VanDerWaalsContact CZ-CB 3.45Å; R406-E429 IonicContact NE-OE2 3.43Å; R406-E429 VanDerWaalsContact NH1-CB 3.31Å; R406-E429 VanDerWaalsContact NH1-CG 3.26Å; R406-I430 PolarHBondContact NH2-O 3.18Å; R406-N431 PolarHBondContact NH2-OD1 3.3Å
407I96.2Very high84.4Confident90 Ų9059.3 Ų59.346%0.46231%0.307SS..Hα-helixtrans-61.9-52.3177.9-60.5166.2000110.1S402 V403 P404 G409 R410 A411S402-I407 WeakPolarHBondContact OG-CD1 3.06Å; V403-I407 WeakPolarHBondContact O-CG1 3.25Å; V403-I407 PolarHBondContact O-N 2.94Å; V403-I407 VanDerWaalsContact O-N 3.09Å; P404-I407 PolarHBondContact O-N 3.26Å; I407-G409 VanDerWaalsContact C-N 3.31Å; I407-G409 PolarHBondContact O-N 2.79Å; I407-R410 PolarHBondContact O-N 2.58Å; I407-A411 PolarHBondContact O-N 3.45Å
408T96.8Very high87.2Confident22 Ų2257.5 Ų57.514%0.13530%0.302CS..Hα-helixtrans-66.3-34.5178.552.10000111.8S327 P404 D405 A411 G412 L599S327-T408 CarbonylContact O-C 3.52Å; S327-T408 PolarHBondContact O-OG1 2.92Å; P404-T408 PolarHBondContact O-N 2.67Å; P404-T408 VanDerWaalsContact O-N 3.09Å; P404-T408 PolarHBondContact O-OG1 3.47Å; D405-T408 WeakPolarHBondContact CA-OG1 3.41Å; D405-T408 PolarHBondContact O-OG1 2.9Å; T408-A411 PolarHBondContact O-N 2.97Å; T408-G412 PolarHBondContact O-N 2.66Å; T408-L599 HydrophobicContact CG2-CD1 4.03Å; T408-L599 HydrophobicContact CG2-CD2 4.45Å
409G97.4Very high89.7Confident0 Ų055.2 Ų55.20%029%0.291CS..Hα-helixtrans-62.3-48.4173.900000112.9F326 S327 D405 R406 I407 A411 G412 L413F326-G409 WeakPolarHBondContact CE1-O 3.35Å; S327-G409 PolarHBondContact O-N 3.03Å; D405-G409 WeakPolarHBondContact O-CA 3.31Å; D405-G409 PolarHBondContact O-N 2.98Å; R406-G409 PolarHBondContact O-N 3.38Å; I407-G409 VanDerWaalsContact C-N 3.31Å; I407-G409 PolarHBondContact O-N 2.79Å; G409-A411 VanDerWaalsContact C-N 3.33Å; G409-A411 PolarHBondContact O-N 3.18Å; G409-G412 PolarHBondContact O-N 3.49Å; G409-L413 PolarHBondContact O-N 3.22Å
410R97.1Very high92.2Very high66 Ų6646.9 Ų46.925%0.24926%0.256CS..Hα-helixtrans-62.4-39.3175.8-72.5179-179.9-178.82.2111.7D398 R406 I407 L413 K414 F427 E429D398-R410 IonicContact OD1-CZ 3.26Å; D398-R410 IonicContact OD1-NH1 2.82Å; D398-R410 PolarHBondContact OD1-NH1 3.26Å; D398-R410 IonicContact OD1-NH2 2.93Å; D398-R410 IonicContact OD2-NH1 3.19Å; R406-R410 WeakPolarHBondContact O-CB 3.39Å; R406-R410 WeakPolarHBondContact O-CG 3.25Å; R406-R410 PolarHBondContact O-N 2.66Å; I407-R410 PolarHBondContact O-N 2.58Å; R410-L413 PolarHBondContact O-N 2.87Å; R410-K414 WeakPolarHBondContact O-CG 3.4Å; R410-K414 PolarHBondContact O-N 3.37Å; R410-F427 HydrophobicContact CG-CD1 4.49Å; R410-F427 HydrophobicContact CG-CE1 3.69Å; R410-F427 HydrophobicContact CG-CZ 4.2Å; R410-E429 IonicContact CZ-OE1 3.24Å; R410-E429 IonicContact CZ-OE2 2.95Å; R410-E429 IonicContact NE-OE1 3.02Å; R410-E429 PolarHBondContact NE-OE1 3.17Å; R410-E429 IonicContact NE-OE2 2.68Å; R410-E429 IonicContact NH2-OE1 3.81Å; R410-E429 PolarHBondContact NH2-OE1 3.1Å; R410-E429 VanDerWaalsContact NH2-OE1 3.09Å; R410-E429 IonicContact NH2-OE2 2.8Å; R410-E429 PolarHBondContact NH2-OE2 3.47Å
411A97.2Very high94.2Very high54 Ų5444.8 Ų44.845%0.44626%0.257SS..Hα-helixtrans-65.3-44.9174.300000111.9I407 T408 G409 L413 K414 E415I407-A411 PolarHBondContact O-N 3.45Å; T408-A411 PolarHBondContact O-N 2.97Å; G409-A411 VanDerWaalsContact C-N 3.33Å; G409-A411 PolarHBondContact O-N 3.18Å; A411-L413 VanDerWaalsContact C-N 3.33Å; A411-L413 PolarHBondContact O-N 3.48Å; A411-K414 WeakPolarHBondContact O-CB 3.4Å; A411-K414 PolarHBondContact O-N 3.27Å; A411-K414 VanDerWaalsContact O-N 3.15Å; A411-E415 PolarHBondContact O-N 3.22Å; A411-E415 VanDerWaalsContact O-N 3.08Å
412G98.1Very high95.7Very high3 Ų347.3 Ų47.33%0.03128%0.275CS..Hα-helixtrans-61-38.8175.500000112.7M333 T408 G409 K414 E415 L416M333-G412 WeakPolarHBondContact CE-O 3.4Å; M333-G412 VanDerWaalsContact SD-CA 3.54Å; T408-G412 PolarHBondContact O-N 2.66Å; G409-G412 PolarHBondContact O-N 3.49Å; G412-K414 VanDerWaalsContact C-N 3.34Å; G412-K414 PolarHBondContact O-N 3.14Å; G412-E415 PolarHBondContact O-N 2.92Å; G412-L416 WeakPolarHBondContact O-CG 3.45Å; G412-L416 PolarHBondContact O-N 3.34Å
413L98Very high96.4Very high23 Ų2344.6 Ų44.612%0.1226%0.255CS..Hα-helixtrans-59.4-43.7172.9176.166.6000112.1L351 G409 R410 A411 E415 L416 K417 W425 F427L351-L413 HydrophobicContact CD1-CD1 4.03Å; G409-L413 PolarHBondContact O-N 3.22Å; R410-L413 PolarHBondContact O-N 2.87Å; A411-L413 VanDerWaalsContact C-N 3.33Å; A411-L413 PolarHBondContact O-N 3.48Å; L413-E415 VanDerWaalsContact C-N 3.29Å; L413-E415 PolarHBondContact O-N 2.89Å; L413-L416 PolarHBondContact O-N 2.74Å; L413-K417 HydrophobicContact CD1-CD 4.46Å; L413-K417 HydrophobicContact CD1-CG 4.44Å; L413-K417 HydrophobicContact CG-CD 4.35Å; L413-K417 WeakPolarHBondContact O-CB 3.31Å; L413-K417 WeakPolarHBondContact O-CG 3.45Å; L413-K417 PolarHBondContact O-N 3.36Å; L413-W425 HydrophobicContact CD1-CB 3.49Å; L413-W425 VanDerWaalsContact CD1-CB 3.49Å; L413-W425 HydrophobicContact CD1-CG 4.24Å; L413-F427 HydrophobicContact CD1-CB 4.12Å; L413-F427 HydrophobicContact CD2-CB 3.54Å; L413-F427 HydrophobicContact CD2-CD1 4.33Å; L413-F427 HydrophobicContact CD2-CG 3.96Å; L413-F427 HydrophobicContact CG-CB 4.31Å
414K97.6Very high96.6Very high160 Ų16047.9 Ų47.970%0.69627%0.272SS*.Hα-helixtrans-61.5-42.1177-68178.6-177.6-176.30110.9R410 A411 G412 K417 A418R410-K414 WeakPolarHBondContact O-CG 3.4Å; R410-K414 PolarHBondContact O-N 3.37Å; A411-K414 WeakPolarHBondContact O-CB 3.4Å; A411-K414 PolarHBondContact O-N 3.27Å; A411-K414 VanDerWaalsContact O-N 3.15Å; G412-K414 VanDerWaalsContact C-N 3.34Å; G412-K414 PolarHBondContact O-N 3.14Å; K414-K417 PolarHBondContact O-N 3.33Å; K414-A418 PolarHBondContact O-N 2.93Å; K414-A418 VanDerWaalsContact O-N 3.09Å
415E97.9Very high96.7Very high18 Ų1847.3 Ų47.38%0.08427%0.266CS..Hα-helixtrans-65.3-45.3176.7-177.9164.8-123.300112.3M333 A411 G412 L413 K417 A418 V419 L593 T594 A595 S596M333-E415 HydrophobicContact CE-CB 4.1Å; M333-E415 HydrophobicContact CE-CG 4.09Å; M333-E415 WeakPolarHBondContact CE-OE2 3.46Å; A411-E415 PolarHBondContact O-N 3.22Å; A411-E415 VanDerWaalsContact O-N 3.08Å; G412-E415 PolarHBondContact O-N 2.92Å; L413-E415 VanDerWaalsContact C-N 3.29Å; L413-E415 PolarHBondContact O-N 2.89Å; E415-K417 VanDerWaalsContact C-N 3.32Å; E415-K417 PolarHBondContact O-N 3.42Å; E415-A418 WeakPolarHBondContact O-CB 3.26Å; E415-A418 PolarHBondContact O-N 3.37Å; E415-V419 WeakPolarHBondContact O-CG2 3.31Å; E415-V419 PolarHBondContact O-N 3.19Å; E415-L593 HydrophobicContact CG-CD2 3.92Å; E415-T594 VanDerWaalsContact OE1-CA 3.28Å; E415-T594 WeakPolarHBondContact OE1-CA 3.43Å; E415-T594 WeakPolarHBondContact OE1-CB 3.47Å; E415-T594 PolarHBondContact OE1-N 3.36Å; E415-T594 PolarHBondContact OE1-OG1 3.14Å; E415-A595 PolarHBondContact OE1-N 3.39Å; E415-S596 WeakPolarHBondContact OE2-CB 3.27Å; E415-S596 PolarHBondContact OE2-N 2.83Å; E415-S596 PolarHBondContact OE2-OG 3.07Å
416L98.3Very high96.8Very high2 Ų248 Ų481%0.0127%0.269CS..Hα-helixtrans-60.4-39.4175.3-72.7174.6000112.4F326 M333 A336 L351 G412 L413 A418 V419 S420 W425F326-L416 HydrophobicContact CE2-CD1 3.74Å; F326-L416 HydrophobicContact CZ-CD1 3.78Å; M333-L416 HydrophobicContact CE-CD2 3.94Å; M333-L416 HydrophobicContact CE-CG 3.75Å; M333-L416 HydrophobicContact SD-CD1 4.3Å; M333-L416 HydrophobicContact SD-CG 4.17Å; A336-L416 HydrophobicContact CB-CD1 3.81Å; A336-L416 HydrophobicContact CB-CD2 3.95Å; L351-L416 HydrophobicContact CD1-CD1 3.76Å; G412-L416 WeakPolarHBondContact O-CG 3.45Å; G412-L416 PolarHBondContact O-N 3.34Å; L413-L416 PolarHBondContact O-N 2.74Å; L416-A418 VanDerWaalsContact C-N 3.29Å; L416-A418 PolarHBondContact O-N 2.74Å; L416-V419 PolarHBondContact O-N 3.36Å; L416-S420 PolarHBondContact O-N 3.34Å; L416-W425 HydrophobicContact CB-CD2 4.29Å; L416-W425 HydrophobicContact CB-CZ2 4.17Å; L416-W425 HydrophobicContact CD1-CD2 4.3Å; L416-W425 HydrophobicContact CD1-CE3 4.18Å; L416-W425 HydrophobicContact CD1-CH2 4.35Å; L416-W425 HydrophobicContact CD1-CZ2 4.46Å; L416-W425 HydrophobicContact CD1-CZ3 4.21Å; L416-W425 HydrophobicContact CD2-CH2 4.35Å; L416-W425 HydrophobicContact CD2-CZ2 4.22Å
417K97.3Very high96.9Very high110 Ų11048.5 Ų48.548%0.47827%0.272SS..Hα-helixtrans-65.8-31174.3-75.1178.7175.2-176.20112.7L413 K414 E415 S420 P421L413-K417 HydrophobicContact CD1-CD 4.46Å; L413-K417 HydrophobicContact CD1-CG 4.44Å; L413-K417 HydrophobicContact CG-CD 4.35Å; L413-K417 WeakPolarHBondContact O-CB 3.31Å; L413-K417 WeakPolarHBondContact O-CG 3.45Å; L413-K417 PolarHBondContact O-N 3.36Å; K414-K417 PolarHBondContact O-N 3.33Å; E415-K417 VanDerWaalsContact C-N 3.32Å; E415-K417 PolarHBondContact O-N 3.42Å; K417-S420 CarbonylContact O-C 3.56Å; K417-P421 VanDerWaalsContact O-CA 3.26Å; K417-P421 WeakPolarHBondContact O-CA 3.49Å
418A97.4Very high97Very high80 Ų8044.2 Ų44.266%0.66125%0.25SC*.Hα-helixtrans-73.5-39.917500000111.7K414 E415 L416K414-A418 PolarHBondContact O-N 2.93Å; K414-A418 VanDerWaalsContact O-N 3.09Å; E415-A418 WeakPolarHBondContact O-CB 3.26Å; E415-A418 PolarHBondContact O-N 3.37Å; L416-A418 VanDerWaalsContact C-N 3.29Å; L416-A418 PolarHBondContact O-N 2.74Å
419V95.6Very high97Very high56 Ų5643.6 Ų43.634%0.33925%0.245SC..Hα-helixtrans-73.3-38.3178.6174.60000111.9T337 E415 L416 L593T337-V419 HydrophobicContact CG2-CG1 4.24Å; E415-V419 WeakPolarHBondContact O-CG2 3.31Å; E415-V419 PolarHBondContact O-N 3.19Å; L416-V419 PolarHBondContact O-N 3.36Å; V419-L593 HydrophobicContact CG2-CD2 4.28Å
420S96Very high97Very high9 Ų943.6 Ų43.66%0.06325%0.245CC..  trans-133.983.3-179-170.10000110.8D340 L416 K417 S422 R423D340-S420 VanDerWaalsContact CG-OG 3.28Å; D340-S420 PolarHBondContact OD1-OG 2.78Å; D340-S420 WeakPolarHBondContact OD2-CB 3.15Å; D340-S420 PolarHBondContact OD2-OG 2.89Å; L416-S420 PolarHBondContact O-N 3.34Å; K417-S420 CarbonylContact O-C 3.56Å; S420-S422 VanDerWaalsContact C-N 3.31Å; S420-S422 PolarHBondContact O-N 3.11Å; S420-R423 PolarHBondContact O-N 3.34Å
421P95.4Very high96.9Very high111 Ų11142.5 Ų42.572%0.72124%0.244SC*.THydrogen-bonded Turntrans-72-22.7-174.327.3-34.9000113.6K417K417-P421 VanDerWaalsContact O-CA 3.26Å; K417-P421 WeakPolarHBondContact O-CA 3.49Å
422S93.9Very high96.9Very high78 Ų7840 Ų4055%0.54522%0.223SC..THydrogen-bonded Turntrans-80.2-17.8178.3520000113.6S420S420-S422 VanDerWaalsContact C-N 3.31Å; S420-S422 PolarHBondContact O-N 3.11Å
423R96.3Very high96.7Very high10 Ų1041.3 Ų41.34%0.03823%0.232CC..SBendtrans-78.1134.4-177.317759.961.7-174-0.3111.5D340 I343 P344 L345 E347 I349 S420 W425D340-R423 PolarHBondContact O-NH2 2.75Å; D340-R423 IonicContact OD1-CZ 3.77Å; D340-R423 IonicContact OD1-NE 2.56Å; D340-R423 PolarHBondContact OD1-NE 3.45Å; D340-R423 IonicContact OD1-NH2 3.08Å; D340-R423 PolarHBondContact OD1-NH2 3Å; I343-R423 PolarHBondContact O-NH2 3.26Å; P344-R423 PolarHBondContact O-NH1 3.13Å; L345-R423 PolarHBondContact O-NH1 3.19Å; E347-R423 PolarHBondContact O-NH1 3.49Å; I349-R423 HydrophobicContact CD1-CG 4.4Å; S420-R423 PolarHBondContact O-N 3.34Å; R423-W425 HydrophobicContact CB-CZ2 4.16Å; R423-W425 HydrophobicContact CG-CD2 3.66Å; R423-W425 HydrophobicContact CG-CE3 4.23Å; R423-W425 HydrophobicContact CG-CG 4.04Å; R423-W425 HydrophobicContact CG-CH2 4.2Å; R423-W425 HydrophobicContact CG-CZ2 3.63Å; R423-W425 HydrophobicContact CG-CZ3 4.47Å; R423-W425 PolarHBondContact O-N 3.36Å
424I95.8Very high96.4Very high75 Ų7542.1 Ų42.139%0.38524%0.236SC..  trans-81.2106.6166.8-55.1171.6000108.8P348 I349P348-I424 WeakPolarHBondContact CA-O 3.26Å; P348-I424 HydrophobicContact CB-CB 4.01Å; P348-I424 HydrophobicContact CB-CG2 3.86Å; P348-I424 HydrophobicContact CG-CB 4.09Å; P348-I424 HydrophobicContact CG-CD1 4.27Å; P348-I424 HydrophobicContact CG-CG2 3.98Å; I349-I424 PolarHBondContact N-O 2.96Å
425W97Very high96.2Very high15 Ų1540.7 Ų40.76%0.05723%0.232CC..EExtended strand (participates in β ladder)trans-98.7109.3173.9-61.7103.5000110.5A336 D340 I349 L351 L413 L416 R423 F427A336-W425 HydrophobicContact CB-CH2 4.1Å; A336-W425 HydrophobicContact CB-CZ3 4.02Å; A336-W425 WeakPolarHBondContact O-CH2 3.27Å; D340-W425 HydrophobicContact CB-CH2 3.91Å; D340-W425 HydrophobicContact CB-CZ2 3.99Å; I349-W425 HydrophobicContact CB-CE3 3.87Å; I349-W425 HydrophobicContact CB-CZ3 3.76Å; I349-W425 HydrophobicContact CD1-CE3 4.43Å; I349-W425 HydrophobicContact CD1-CH2 3.83Å; I349-W425 HydrophobicContact CD1-CZ3 3.66Å; I349-W425 HydrophobicContact CG1-CZ3 4.29Å; I349-W425 HydrophobicContact CG2-CE3 4.13Å; I349-W425 HydrophobicContact CG2-CZ3 3.76Å; L351-W425 HydrophobicContact CD1-CB 4.34Å; L351-W425 HydrophobicContact CD1-CD2 4.49Å; L351-W425 HydrophobicContact CD1-CE3 3.95Å; L351-W425 HydrophobicContact CD2-CE3 3.92Å; L351-W425 HydrophobicContact CD2-CZ3 4.05Å; L351-W425 HydrophobicContact CG-CE3 4.04Å; L413-W425 HydrophobicContact CD1-CB 3.49Å; L413-W425 VanDerWaalsContact CD1-CB 3.49Å; L413-W425 HydrophobicContact CD1-CG 4.24Å; L416-W425 HydrophobicContact CB-CD2 4.29Å; L416-W425 HydrophobicContact CB-CZ2 4.17Å; L416-W425 HydrophobicContact CD1-CD2 4.3Å; L416-W425 HydrophobicContact CD1-CE3 4.18Å; L416-W425 HydrophobicContact CD1-CH2 4.35Å; L416-W425 HydrophobicContact CD1-CZ2 4.46Å; L416-W425 HydrophobicContact CD1-CZ3 4.21Å; L416-W425 HydrophobicContact CD2-CH2 4.35Å; L416-W425 HydrophobicContact CD2-CZ2 4.22Å; R423-W425 HydrophobicContact CB-CZ2 4.16Å; R423-W425 HydrophobicContact CG-CD2 3.66Å; R423-W425 HydrophobicContact CG-CE3 4.23Å; R423-W425 HydrophobicContact CG-CG 4.04Å; R423-W425 HydrophobicContact CG-CH2 4.2Å; R423-W425 HydrophobicContact CG-CZ2 3.63Å; R423-W425 HydrophobicContact CG-CZ3 4.47Å; R423-W425 PolarHBondContact O-N 3.36Å; W425-F427 PolarHBondContact O-N 3.05Å
426N97.2Very high96.1Very high25 Ų2542.3 Ų42.313%0.13424%0.239CC..EExtended strand (participates in β ladder)trans-88.792.1176.4-70.6-22.8000109.5P348 I349 D350 L351 V428 L474 Y483P348-N426 VanDerWaalsContact CB-ND2 3.34Å; P348-N426 WeakPolarHBondContact CB-ND2 3.36Å; I349-N426 PolarHBondContact O-N 3.38Å; D350-N426 WeakPolarHBondContact OD1-CB 3.21Å; D350-N426 PolarHBondContact OD1-ND2 2.93Å; L351-N426 PolarHBondContact N-O 2.77Å; N426-V428 PolarHBondContact O-N 3.1Å; N426-V428 VanDerWaalsContact O-N 3.16Å; N426-L474 HydrophobicContact CB-CD2 4.03Å; N426-Y483 PolarHBondContact ND2-OH 3.28Å
427F97.8Very high95.9Very high12 Ų1242.2 Ų42.25%0.05324%0.239CC..EExtended strand (participates in β ladder)trans-7999.2175.6-173.6-108.8000110.8F326 L351 N353 R410 L413 W425 E429 L474F326-F427 HydrophobicContact CD1-CD2 4.1Å; F326-F427 AromaticContact CD1-CE2 3.77Å; F326-F427 HydrophobicContact CD1-CE2 3.77Å; F326-F427 HydrophobicContact CE1-CD2 4.23Å; F326-F427 AromaticContact CE1-CE2 3.95Å; F326-F427 HydrophobicContact CE1-CE2 3.95Å; L351-F427 HydrophobicContact CB-CD2 4Å; L351-F427 HydrophobicContact CD1-CD2 4.42Å; N353-F427 HydrophobicContact CB-CD2 4.48Å; N353-F427 HydrophobicContact CB-CE2 3.59Å; N353-F427 HydrophobicContact CB-CZ 3.65Å; R410-F427 HydrophobicContact CG-CD1 4.49Å; R410-F427 HydrophobicContact CG-CE1 3.69Å; R410-F427 HydrophobicContact CG-CZ 4.2Å; L413-F427 HydrophobicContact CD1-CB 4.12Å; L413-F427 HydrophobicContact CD2-CB 3.54Å; L413-F427 HydrophobicContact CD2-CD1 4.33Å; L413-F427 HydrophobicContact CD2-CG 3.96Å; L413-F427 HydrophobicContact CG-CB 4.31Å; W425-F427 PolarHBondContact O-N 3.05Å; F427-E429 HydrophobicContact CD1-CG 3.81Å; F427-E429 HydrophobicContact CE1-CG 3.78Å; F427-E429 VanDerWaalsContact CE1-OE1 3.31Å; F427-E429 WeakPolarHBondContact CE1-OE1 3.45Å; F427-E429 PolarHBondContact O-N 3.46Å; F427-L474 WeakPolarHBondContact O-CD2 3.32Å
428V97.9Very high95.8Very high0 Ų040 Ų400%023%0.23CC..EExtended strand (participates in β ladder)trans-85.8109.9-175.6-170.40000109.7D350 L351 L352 N353 N426 I430 L474 Y483D350-V428 HydrophobicContact CB-CG2 4.49Å; L351-V428 PolarHBondContact O-N 3.12Å; L352-V428 HydrophobicContact CD2-CB 3.94Å; L352-V428 HydrophobicContact CD2-CG1 4.47Å; L352-V428 HydrophobicContact CD2-CG2 3.85Å; N353-V428 PolarHBondContact N-O 3.01Å; N353-V428 VanDerWaalsContact N-O 3.13Å; N426-V428 PolarHBondContact O-N 3.1Å; N426-V428 VanDerWaalsContact O-N 3.16Å; V428-I430 HydrophobicContact CG1-CG1 4.01Å; V428-I430 PolarHBondContact O-N 3.07Å; V428-L474 HydrophobicContact CG2-CD2 4.06Å; V428-Y483 HydrophobicContact CB-CD1 4.46Å; V428-Y483 HydrophobicContact CG1-CD1 4.06Å; V428-Y483 HydrophobicContact CG2-CD1 3.53Å; V428-Y483 HydrophobicContact CG2-CE1 3.66Å
429E97.4Very high95.6Very high9 Ų943.1 Ų43.14%0.04223%0.229CC..EExtended strand (participates in β ladder)trans-84.396.5178-53.8-151.6160.200112.5R406 R410 F427 G472 W473 V475R406-E429 WeakPolarHBondContact CD-OE1 3.37Å; R406-E429 VanDerWaalsContact CZ-CB 3.45Å; R406-E429 IonicContact NE-OE2 3.43Å; R406-E429 VanDerWaalsContact NH1-CB 3.31Å; R406-E429 VanDerWaalsContact NH1-CG 3.26Å; R410-E429 IonicContact CZ-OE1 3.24Å; R410-E429 IonicContact CZ-OE2 2.95Å; R410-E429 IonicContact NE-OE1 3.02Å; R410-E429 PolarHBondContact NE-OE1 3.17Å; R410-E429 IonicContact NE-OE2 2.68Å; R410-E429 IonicContact NH2-OE1 3.81Å; R410-E429 PolarHBondContact NH2-OE1 3.1Å; R410-E429 VanDerWaalsContact NH2-OE1 3.09Å; R410-E429 IonicContact NH2-OE2 2.8Å; R410-E429 PolarHBondContact NH2-OE2 3.47Å; F427-E429 HydrophobicContact CD1-CG 3.81Å; F427-E429 HydrophobicContact CE1-CG 3.78Å; F427-E429 VanDerWaalsContact CE1-OE1 3.31Å; F427-E429 WeakPolarHBondContact CE1-OE1 3.45Å; F427-E429 PolarHBondContact O-N 3.46Å; E429-G472 CarbonylContact O-C 3.56Å; E429-G472 VanDerWaalsContact O-CA 3.25Å; E429-G472 WeakPolarHBondContact O-CA 3.49Å; E429-W473 HydrophobicContact CB-CB 4.43Å; E429-W473 WeakPolarHBondContact CB-O 3.47Å; E429-W473 PolarHBondContact N-O 3.11Å; E429-W473 PolarHBondContact O-N 3.19Å; E429-V475 HydrophobicContact CG-CG2 4.39Å
430I97.5Very high95.7Very high0 Ų042.1 Ų42.10%022%0.221CC..EExtended strand (participates in β ladder)trans-91.9109179.7-55.3167.7000108.6L352 N353 V354 A355 R406 V428 V432 A467L352-I430 HydrophobicContact CB-CD1 4.19Å; N353-I430 PolarHBondContact O-N 3.18Å; V354-I430 CarbonylContact C-O 3.6Å; V354-I430 WeakPolarHBondContact CA-O 3.33Å; V354-I430 HydrophobicContact CB-CB 4.43Å; V354-I430 HydrophobicContact CG2-CB 4.48Å; V354-I430 HydrophobicContact CG2-CG2 4.14Å; A355-I430 PolarHBondContact N-O 3.45Å; R406-I430 PolarHBondContact NH2-O 3.18Å; V428-I430 HydrophobicContact CG1-CG1 4.01Å; V428-I430 PolarHBondContact O-N 3.07Å; I430-V432 HydrophobicContact CG2-CG2 4.28Å; I430-A467 WeakPolarHBondContact CD1-O 3.46Å
431N96.2Very high95.6Very high42 Ų4241.8 Ų41.823%0.22522%0.219CC..EExtended strand (participates in β ladder)trans-110.9125.7-177.8-66.7-24.3000108.7A355 I357 R406A355-N431 WeakPolarHBondContact O-CA 3.38Å; I357-N431 HydrophobicContact CD1-CB 3.62Å; R406-N431 PolarHBondContact NH2-OD1 3.3Å
432V95.9Very high95.4Very high1 Ų143.8 Ų43.81%0.00621%0.212CC..EExtended strand (participates in β ladder)trans-119123.4-173.8-174.50000109.1V354 A355 F356 I357 I430 E436 L437 F466V354-V432 HydrophobicContact CG2-CG2 3.97Å; A355-V432 PolarHBondContact O-N 3.33Å; F356-V432 WeakPolarHBondContact CA-O 3.43Å; F356-V432 HydrophobicContact CD1-CB 3.8Å; F356-V432 HydrophobicContact CD1-CG1 3.88Å; F356-V432 HydrophobicContact CE1-CB 3.85Å; F356-V432 HydrophobicContact CE1-CG1 3.71Å; F356-V432 HydrophobicContact CE1-CG2 4.2Å; F356-V432 HydrophobicContact CG-CB 4.46Å; F356-V432 HydrophobicContact CZ-CG2 4.47Å; I357-V432 PolarHBondContact N-O 3.32Å; I430-V432 HydrophobicContact CG2-CG2 4.28Å; V432-E436 HydrophobicContact CG1-CB 4.34Å; V432-E436 HydrophobicContact CG1-CG 4.39Å; V432-L437 HydrophobicContact CG1-CB 4.18Å; V432-F466 HydrophobicContact CB-CD1 4.41Å; V432-F466 HydrophobicContact CG1-CD1 3.95Å; V432-F466 HydrophobicContact CG1-CD2 4.12Å; V432-F466 HydrophobicContact CG1-CE1 3.66Å; V432-F466 HydrophobicContact CG1-CE2 3.87Å; V432-F466 HydrophobicContact CG1-CG 4.17Å; V432-F466 HydrophobicContact CG1-CZ 3.62Å; V432-F466 HydrophobicContact CG2-CB 3.84Å; V432-F466 HydrophobicContact CG2-CD1 3.51Å; V432-F466 HydrophobicContact CG2-CD2 4.25Å; V432-F466 HydrophobicContact CG2-CE1 4.08Å; V432-F466 HydrophobicContact CG2-CG 3.61Å
433S94.4Very high95.2Very high31 Ų3144.1 Ų44.122%0.21721%0.211CC..EExtended strand (participates in β ladder)trans-79.1163174.275.50000111.4E435 E436 L437S433-E435 VanDerWaalsContact C-N 3.31Å; S433-E435 PolarHBondContact O-N 3.44Å; S433-E436 PolarHBondContact O-N 3.48Å; S433-E436 WeakPolarHBondContact OG-CB 3.34Å; S433-E436 PolarHBondContact OG-N 3.09Å; S433-L437 PolarHBondContact O-N 3.49Å
434M91.8Very high95.1Very high40 Ų4044.8 Ų44.820%0.19721%0.213CC..Hα-helixtrans-58.1-45.3173.81786081.100111.9E436 L437 Q438 M613 E614M434-E436 VanDerWaalsContact C-N 3.35Å; M434-E436 PolarHBondContact O-N 3.23Å; M434-L437 PolarHBondContact O-N 2.87Å; M434-Q438 HydrophobicContact CG-CG 4.38Å; M434-Q438 WeakPolarHBondContact O-CB 3.18Å; M434-Q438 WeakPolarHBondContact O-CG 3.49Å; M434-Q438 PolarHBondContact O-N 3.44Å; M434-Q438 HydrophobicContact SD-CG 3.93Å; M434-M613 HydrophobicContact CB-CE 4.36Å; M434-M613 HydrophobicContact CB-SD 4.41Å; M434-M613 HydrophobicContact CE-CB 3.77Å; M434-M613 HydrophobicContact CE-CE 3.96Å; M434-M613 HydrophobicContact CE-CG 3.44Å; M434-M613 VanDerWaalsContact CE-CG 3.44Å; M434-M613 WeakPolarHBondContact CE-O 3.48Å; M434-M613 HydrophobicContact CE-SD 4.19Å; M434-M613 HydrophobicContact SD-CE 3.71Å; M434-M613 HydrophobicContact SD-CG 4.44Å; M434-E614 HydrophobicContact CE-CG 3.47Å; M434-E614 VanDerWaalsContact CE-CG 3.47Å; M434-E614 HydrophobicContact SD-CG 3.66Å
435E93.1Very high95.1Very high130 Ų13041.2 Ų41.261%0.60720%0.195SC*.Hα-helixtrans-62.7-43.9-178.1-58.4-175.6161.200111.4S433 Q438 K439S433-E435 VanDerWaalsContact C-N 3.31Å; S433-E435 PolarHBondContact O-N 3.44Å; E435-Q438 PolarHBondContact O-N 2.98Å; E435-K439 VanDerWaalsContact O-CB 3.3Å; E435-K439 WeakPolarHBondContact O-CB 3.18Å; E435-K439 PolarHBondContact O-N 3.08Å
436E95.8Very high94.8Very high52 Ų5240.5 Ų40.524%0.24319%0.192CC..Hα-helixtrans-62.8-46.6176.9-175.4-178.4-168.200111.2V432 S433 M434 Q438 K439 L440 F466 R469V432-E436 HydrophobicContact CG1-CB 4.34Å; V432-E436 HydrophobicContact CG1-CG 4.39Å; S433-E436 PolarHBondContact O-N 3.48Å; S433-E436 WeakPolarHBondContact OG-CB 3.34Å; S433-E436 PolarHBondContact OG-N 3.09Å; M434-E436 VanDerWaalsContact C-N 3.35Å; M434-E436 PolarHBondContact O-N 3.23Å; E436-Q438 PolarHBondContact O-N 3.4Å; E436-K439 PolarHBondContact O-N 2.83Å; E436-L440 HydrophobicContact CG-CD1 3.73Å; E436-L440 WeakPolarHBondContact O-CB 3.17Å; E436-L440 PolarHBondContact O-N 3.43Å; E436-F466 HydrophobicContact CG-CE1 3.85Å; E436-F466 HydrophobicContact CG-CZ 4.08Å; E436-R469 IonicContact OE1-CZ 2.92Å; E436-R469 IonicContact OE1-NH1 2.93Å; E436-R469 PolarHBondContact OE1-NH1 3.01Å; E436-R469 IonicContact OE1-NH2 3.51Å; E436-R469 PolarHBondContact OE1-NH2 3.33Å; E436-R469 IonicContact OE2-NH2 2.76Å
437L95.2Very high94.5Very high1 Ų140.8 Ų40.81%0.00519%0.193CC..Hα-helixtrans-56.9-52.5175.2172.161.5000110.6F356 V432 S433 M434 K439 L440 R441 C462 F466 I610 M613F356-L437 HydrophobicContact CD1-CD2 4.19Å; F356-L437 HydrophobicContact CE1-CB 4.44Å; F356-L437 HydrophobicContact CE1-CD1 4.05Å; F356-L437 HydrophobicContact CE1-CD2 4.2Å; F356-L437 HydrophobicContact CE1-CG 4.44Å; V432-L437 HydrophobicContact CG1-CB 4.18Å; S433-L437 PolarHBondContact O-N 3.49Å; M434-L437 PolarHBondContact O-N 2.87Å; L437-K439 VanDerWaalsContact C-N 3.33Å; L437-K439 PolarHBondContact O-N 3.44Å; L437-L440 PolarHBondContact O-N 3.42Å; L437-R441 HydrophobicContact CD1-CB 4.35Å; L437-R441 WeakPolarHBondContact O-CB 3.42Å; L437-R441 PolarHBondContact O-N 2.75Å; L437-C462 HydrophobicContact CD1-CB 3.77Å; L437-F466 HydrophobicContact CB-CE2 4.47Å; L437-F466 HydrophobicContact CD1-CD2 4.49Å; L437-F466 HydrophobicContact CD1-CE2 3.76Å; L437-I610 HydrophobicContact CD1-CD1 4.17Å; L437-I610 HydrophobicContact CD2-CD1 4Å; L437-I610 HydrophobicContact CD2-CG1 3.99Å; L437-M613 HydrophobicContact CB-CE 3.75Å; L437-M613 HydrophobicContact CD2-CE 3.12Å; L437-M613 HydrophobicContact CG-CE 4.02Å
438Q93.7Very high94.4Very high63 Ų6340.3 Ų40.329%0.29419%0.191SC..Hα-helixtrans-61.5-42.5-175.5-74.1-179.2-11.900112.2M434 E435 E436 R442 E614M434-Q438 HydrophobicContact CG-CG 4.38Å; M434-Q438 WeakPolarHBondContact O-CB 3.18Å; M434-Q438 WeakPolarHBondContact O-CG 3.49Å; M434-Q438 PolarHBondContact O-N 3.44Å; M434-Q438 HydrophobicContact SD-CG 3.93Å; E435-Q438 PolarHBondContact O-N 2.98Å; E436-Q438 PolarHBondContact O-N 3.4Å; Q438-R442 WeakPolarHBondContact O-CG 3.47Å; Q438-R442 PolarHBondContact O-N 3.13Å; Q438-E614 WeakPolarHBondContact CG-OE1 3.41Å; Q438-E614 PolarHBondContact NE2-OE1 2.92Å
439K94.7Very high94.2Very high146 Ų14640.3 Ų40.364%0.63519%0.191SC*.Hα-helixtrans-62.3-60.4177.2-178.5179.8178.4-1790110.6E435 E436 L437 R441 R442 T443E435-K439 VanDerWaalsContact O-CB 3.3Å; E435-K439 WeakPolarHBondContact O-CB 3.18Å; E435-K439 PolarHBondContact O-N 3.08Å; E436-K439 PolarHBondContact O-N 2.83Å; L437-K439 VanDerWaalsContact C-N 3.33Å; L437-K439 PolarHBondContact O-N 3.44Å; K439-R441 VanDerWaalsContact C-N 3.33Å; K439-R441 PolarHBondContact O-N 3.25Å; K439-R442 PolarHBondContact O-N 2.93Å; K439-T443 WeakPolarHBondContact O-CG2 3.13Å; K439-T443 PolarHBondContact O-N 3.34Å; K439-T443 PolarHBondContact O-OG1 2.91Å
440L96Very high93.8Very high35 Ų3541 Ų4118%0.18319%0.194CC..Hα-helixtrans-69.1-31.4-172.8-68.4172.9000112.5E436 L437 R442 R444 I445 W465 F466E436-L440 HydrophobicContact CG-CD1 3.73Å; E436-L440 WeakPolarHBondContact O-CB 3.17Å; E436-L440 PolarHBondContact O-N 3.43Å; L437-L440 PolarHBondContact O-N 3.42Å; L440-R442 VanDerWaalsContact C-N 3.35Å; L440-R442 PolarHBondContact O-N 3Å; L440-R444 WeakPolarHBondContact O-CA 3.49Å; L440-R444 WeakPolarHBondContact O-CB 3.35Å; L440-R444 PolarHBondContact O-N 3.33Å; L440-I445 HydrophobicContact CB-CD1 4.38Å; L440-I445 PolarHBondContact O-N 3.38Å; L440-W465 HydrophobicContact CB-CZ3 4.42Å; L440-W465 HydrophobicContact CD1-CH2 3.87Å; L440-W465 HydrophobicContact CD1-CZ3 3.75Å; L440-W465 HydrophobicContact CD2-CH2 4.31Å; L440-W465 HydrophobicContact CG-CH2 4.47Å; L440-F466 HydrophobicContact CB-CZ 3.99Å; L440-F466 HydrophobicContact CD1-CE1 3.6Å; L440-F466 HydrophobicContact CD1-CZ 3.71Å; L440-F466 HydrophobicContact CG-CZ 4.43Å
441R94.6Very high93.5Very high1 Ų142.5 Ų42.50%0.00420%0.204CC..Iπ-helixtrans-57.7-47.9171.5178.3177.355.4-161-3.1112L437 K439 C446 D458 E614 R626 L627L437-R441 HydrophobicContact CD1-CB 4.35Å; L437-R441 WeakPolarHBondContact O-CB 3.42Å; L437-R441 PolarHBondContact O-N 2.75Å; K439-R441 VanDerWaalsContact C-N 3.33Å; K439-R441 PolarHBondContact O-N 3.25Å; R441-C446 WeakPolarHBondContact O-CB 3.32Å; R441-C446 PolarHBondContact O-N 2.85Å; R441-C446 PolarHBondContact O-SG 3.19Å; R441-D458 WeakPolarHBondContact CD-OD1 3.47Å; R441-D458 IonicContact NH1-OD2 3.34Å; R441-D458 PolarHBondContact NH1-OD2 2.86Å; R441-E614 IonicContact CZ-OE1 3.19Å; R441-E614 IonicContact CZ-OE2 3.81Å; R441-E614 VanDerWaalsContact CZ-OE2 3.24Å; R441-E614 IonicContact NH1-OE1 2.84Å; R441-E614 IonicContact NH1-OE2 3.81Å; R441-E614 PolarHBondContact NH1-OE2 3.44Å; R441-E614 VanDerWaalsContact NH2-CD 3.27Å; R441-E614 IonicContact NH2-OE1 2.68Å; R441-E614 PolarHBondContact NH2-OE1 2.81Å; R441-E614 IonicContact NH2-OE2 2.85Å; R441-E614 PolarHBondContact NH2-OE2 2.96Å; R441-R626 VanDerWaalsContact NH1-CD 3.27Å; R441-R626 VanDerWaalsContact NH1-NE 3.19Å; R441-L627 HydrophobicContact CG-CD2 4.31Å
442R91Very high93.3Very high154 Ų15441.9 Ų41.958%0.58120%0.2SC*.Iπ-helixtrans-75.6-35.4-176.3-72.2176.8-179.9169.43.5113.3Q438 K439 L440 C446Q438-R442 WeakPolarHBondContact O-CG 3.47Å; Q438-R442 PolarHBondContact O-N 3.13Å; K439-R442 PolarHBondContact O-N 2.93Å; L440-R442 VanDerWaalsContact C-N 3.35Å; L440-R442 PolarHBondContact O-N 3Å; R442-C446 PolarHBondContact O-SG 3.09Å
443T90.8Very high93.1Very high85 Ų8544.4 Ų44.452%0.52121%0.214SC..Iπ-helixtrans-95.6-16.9-173.763.40000113.4K439K439-T443 WeakPolarHBondContact O-CG2 3.13Å; K439-T443 PolarHBondContact O-N 3.34Å; K439-T443 PolarHBondContact O-OG1 2.91Å
444R93.9Very high93.1Very high23 Ų2343.8 Ų43.89%0.08721%0.209CC..Iπ-helixtrans-136.4-60.6-174.3-172.260-177.4163.71.7114.1Y25 N26 L440 C446 H447 L448 W465 D543Y25-R444 VanDerWaalsContact CD1-NH1 3.28Å; Y25-R444 VanDerWaalsContact CE1-CZ 3.41Å; N26-R444 VanDerWaalsContact OD1-CZ 3.25Å; N26-R444 PolarHBondContact OD1-NH1 3.19Å; N26-R444 PolarHBondContact OD1-NH2 3.19Å; L440-R444 WeakPolarHBondContact O-CA 3.49Å; L440-R444 WeakPolarHBondContact O-CB 3.35Å; L440-R444 PolarHBondContact O-N 3.33Å; R444-C446 VanDerWaalsContact C-N 3.32Å; R444-C446 PolarHBondContact O-N 3.41Å; R444-H447 PolarHBondContact O-N 3.32Å; R444-L448 HydrophobicContact CG-CD1 4.34Å; R444-W465 HydrophobicContact CG-CZ2 3.94Å; R444-D543 IonicContact CZ-OD1 3.45Å; R444-D543 IonicContact CZ-OD2 3.91Å; R444-D543 IonicContact NE-OD1 2.98Å; R444-D543 PolarHBondContact NE-OD1 2.87Å; R444-D543 IonicContact NE-OD2 3.99Å; R444-D543 PolarHBondContact NE-OD2 2.99Å; R444-D543 IonicContact NH2-OD1 3.05Å; R444-D543 PolarHBondContact NH2-OD1 3.28Å
445I95.3Very high93.1Very high0 Ų042.7 Ų42.70%020%0.204CC..Iπ-helixtrans-69-32.4-164.8-51.6170.9000111.3L440 H447 L448 I449 C462 W465 F466 V540L440-I445 HydrophobicContact CB-CD1 4.38Å; L440-I445 PolarHBondContact O-N 3.38Å; I445-H447 PolarHBondContact O-N 3.48Å; I445-L448 PolarHBondContact O-N 3.46Å; I445-I449 HydrophobicContact CG2-CD1 3.65Å; I445-I449 HydrophobicContact CG2-CG1 3.95Å; I445-I449 PolarHBondContact O-N 3.09Å; I445-I449 VanDerWaalsContact O-N 3.09Å; I445-C462 HydrophobicContact CD1-CB 4.37Å; I445-W465 HydrophobicContact CD1-CB 4.15Å; I445-W465 HydrophobicContact CD1-CD2 3.78Å; I445-W465 HydrophobicContact CD1-CE3 3.69Å; I445-W465 HydrophobicContact CD1-CG 4Å; I445-W465 HydrophobicContact CD1-CZ3 4.4Å; I445-W465 HydrophobicContact CG1-CB 4.31Å; I445-W465 HydrophobicContact CG1-CD2 3.69Å; I445-W465 HydrophobicContact CG1-CE3 4.07Å; I445-W465 HydrophobicContact CG1-CG 3.79Å; I445-W465 HydrophobicContact CG2-CB 4.37Å; I445-W465 HydrophobicContact CG2-CG 4.48Å; I445-F466 HydrophobicContact CD1-CD2 4.25Å; I445-F466 HydrophobicContact CD1-CE2 3.79Å; I445-F466 HydrophobicContact CD1-CZ 4.45Å; I445-V540 HydrophobicContact CG2-CG1 4.47Å
446C91.8Very high93.1Very high1 Ų139.1 Ų39.11%0.00719%0.189CC..Hα-helixtrans-53.1-39.5176.159.60000113.1R441 R442 R444 L448 Q450 L627R441-C446 WeakPolarHBondContact O-CB 3.32Å; R441-C446 PolarHBondContact O-N 2.85Å; R441-C446 PolarHBondContact O-SG 3.19Å; R442-C446 PolarHBondContact O-SG 3.09Å; R444-C446 VanDerWaalsContact C-N 3.32Å; R444-C446 PolarHBondContact O-N 3.41Å; C446-L448 VanDerWaalsContact C-N 3.28Å; C446-L448 PolarHBondContact O-N 2.76Å; C446-Q450 WeakPolarHBondContact O-CG 3.47Å; C446-L627 HydrophobicContact CB-CD2 4.26Å
447H90.8Very high93Very high30 Ų3036.8 Ų36.814%0.13918%0.178CC..Hα-helixtrans-67.6-28.8178.4-58.4-68.2000113.1Q162 R444 I445 I629Q162-H447 VanDerWaalsContact CB-ND1 3.31Å; Q162-H447 WeakPolarHBondContact CB-ND1 3.43Å; Q162-H447 PolarHBondContact N-ND1 2.93Å; R444-H447 PolarHBondContact O-N 3.32Å; I445-H447 PolarHBondContact O-N 3.48Å; H447-I629 WeakPolarHBondContact CE1-CD1 3.39Å
448L94.9Very high93Very high2 Ų236.9 Ų36.91%0.0118%0.179CC..Hα-helixtrans-89.3-25.4-174.3-55.3172.2000112.5V159 R444 I445 C446 R539 V540 D543V159-L448 HydrophobicContact CG2-CD2 3.85Å; R444-L448 HydrophobicContact CG-CD1 4.34Å; I445-L448 PolarHBondContact O-N 3.46Å; C446-L448 VanDerWaalsContact C-N 3.28Å; C446-L448 PolarHBondContact O-N 2.76Å; L448-R539 HydrophobicContact CB-CB 4.46Å; L448-R539 VanDerWaalsContact O-CB 3.32Å; L448-R539 WeakPolarHBondContact O-CB 3.39Å; L448-R539 WeakPolarHBondContact O-CD 3.42Å; L448-R539 PolarHBondContact O-NE 2.95Å; L448-V540 HydrophobicContact CB-CG1 3.87Å; L448-D543 HydrophobicContact CD1-CB 3.56Å; L448-D543 VanDerWaalsContact CD1-CG 3.46Å; L448-D543 WeakPolarHBondContact CD1-OD2 3.43Å; L448-D543 HydrophobicContact CD2-CB 4.3Å
449I93.6Very high93Very high0 Ų034.2 Ų34.20%017%0.167CC..Hα-helixtrans-75.6-35.3179.1-67.9173.5000111.1I445 L452 D457 R536 R539 V540 L627I445-I449 HydrophobicContact CG2-CD1 3.65Å; I445-I449 HydrophobicContact CG2-CG1 3.95Å; I445-I449 PolarHBondContact O-N 3.09Å; I445-I449 VanDerWaalsContact O-N 3.09Å; I449-L452 HydrophobicContact CG2-CB 4.04Å; I449-L452 WeakPolarHBondContact CG2-O 3.42Å; I449-L452 PolarHBondContact O-N 2.83Å; I449-D457 HydrophobicContact CG2-CB 3.84Å; I449-R536 HydrophobicContact CG1-CG 4.37Å; I449-R536 HydrophobicContact CG2-CG 4.42Å; I449-R539 PolarHBondContact O-NH2 3.24Å; I449-V540 HydrophobicContact CG1-CG1 4.35Å; I449-L627 HydrophobicContact CD1-CD1 4.46Å; I449-L627 HydrophobicContact CD1-CD2 3.79Å; I449-L627 HydrophobicContact CG2-CD1 4.01Å
450Q89.6Confident93Very high23 Ų2328.9 Ų28.911%0.10715%0.145CC..THydrogen-bonded Turntrans-48.5137.8178.3-73.7-65.2-53.500112.6C446 L452 R539C446-Q450 WeakPolarHBondContact O-CG 3.47Å; Q450-L452 PolarHBondContact NE2-O 3.21Å; Q450-R539 PolarHBondContact O-NE 2.8Å; Q450-R539 VanDerWaalsContact O-NE 3.09Å; Q450-R539 PolarHBondContact O-NH1 3.29Å; Q450-R539 PolarHBondContact O-NH2 3.03Å
451P90.8Very high93.1Very high32 Ų3227.2 Ų27.221%0.20814%0.136CC..THydrogen-bonded Turncis-84.5-1.214.634.1-39.8000115.4W170 E172W170-P451 VanDerWaalsContact O-CB 3.31Å; W170-P451 WeakPolarHBondContact O-CB 3.43Å; E172-P451 HydrophobicContact CB-CG 4.31Å
452L92.1Very high93.2Very high29 Ų2927.1 Ų27.115%0.15214%0.136CC..  trans-69.9147.7178.4-58.9-176000110.9I449 Q450 D457 R536I449-L452 HydrophobicContact CG2-CB 4.04Å; I449-L452 WeakPolarHBondContact CG2-O 3.42Å; I449-L452 PolarHBondContact O-N 2.83Å; Q450-L452 PolarHBondContact NE2-O 3.21Å; L452-D457 HydrophobicContact CB-CB 3.81Å; L452-D457 HydrophobicContact CD1-CB 4.43Å; L452-D457 WeakPolarHBondContact CD1-OD1 3.46Å; L452-R536 HydrophobicContact CD1-CB 3.9Å
453D91.8Very high93.5Very high54 Ų5419.8 Ų19.829%0.28911%0.108SC..  trans-147.411.9-171.371.2-6.7000114.4K623 C624D453-K623 WeakPolarHBondContact OD2-CE 3.4Å; D453-K623 IonicContact OD2-NZ 3.66Å; D453-C624 WeakPolarHBondContact O-CB 3.38Å; D453-C624 PolarHBondContact O-N 2.92Å
454T93.1Very high93.9Very high18 Ų1816 Ų1611%0.119%0.085CC..BIsolated β-bridgetrans-86.1164.6179.974.70000112.9L456 D457 D458 D622T454-L456 PolarHBondContact O-N 2.93Å; T454-L456 PolarHBondContact OG1-N 2.98Å; T454-D457 WeakPolarHBondContact CB-OD2 3.49Å; T454-D457 PolarHBondContact N-OD2 2.95Å; T454-D457 PolarHBondContact O-N 3.2Å; T454-D457 VanDerWaalsContact O-N 3.1Å; T454-D457 PolarHBondContact OG1-N 2.92Å; T454-D457 PolarHBondContact OG1-OD2 2.88Å; T454-D458 PolarHBondContact O-N 2.81Å; T454-D622 CarbonylContact C-O 3.46Å; T454-D622 VanDerWaalsContact CA-O 3.25Å; T454-D622 WeakPolarHBondContact CA-O 3.46Å
455V92.8Very high94.1Very high17 Ų1715.5 Ų15.510%0.1038%0.083CC..Hα-helixtrans-60.4-33.8174.2170.30000112.1S459 E618 D622 C624V455-S459 WeakPolarHBondContact O-CB 3.44Å; V455-S459 PolarHBondContact O-N 3.49Å; V455-S459 PolarHBondContact O-OG 3.39Å; V455-E618 HydrophobicContact CG2-CB 4Å; V455-D622 PolarHBondContact N-O 3.4Å; V455-C624 HydrophobicContact CG2-CB 4.05Å
456L92.1Very high94.3Very high55 Ų5515.5 Ų15.529%0.2888%0.083SC..Hα-helixtrans-64.1-42.7173.6-175.258.7000111.3T454 S459 I460 A620T454-L456 PolarHBondContact O-N 2.93Å; T454-L456 PolarHBondContact OG1-N 2.98Å; L456-S459 PolarHBondContact O-N 3.21Å; L456-I460 HydrophobicContact CD1-CD1 3.56Å; L456-I460 HydrophobicContact CD1-CG1 4.08Å; L456-I460 HydrophobicContact CG-CD1 3.9Å; L456-I460 WeakPolarHBondContact O-CG1 3.35Å; L456-I460 PolarHBondContact O-N 3.25Å; L456-A620 HydrophobicContact CB-CB 4.18Å; L456-A620 WeakPolarHBondContact CB-O 3.37Å; L456-A620 PolarHBondContact N-O 3.22Å
457D94.3Very high94.6Very high4 Ų415.6 Ų15.62%0.0218%0.084CC..Hα-helixtrans-68.1-40.1-179.3-60.6-49.8000111.9I449 L452 T454 G461 R536I449-D457 HydrophobicContact CG2-CB 3.84Å; L452-D457 HydrophobicContact CB-CB 3.81Å; L452-D457 HydrophobicContact CD1-CB 4.43Å; L452-D457 WeakPolarHBondContact CD1-OD1 3.46Å; T454-D457 WeakPolarHBondContact CB-OD2 3.49Å; T454-D457 PolarHBondContact N-OD2 2.95Å; T454-D457 PolarHBondContact O-N 3.2Å; T454-D457 VanDerWaalsContact O-N 3.1Å; T454-D457 PolarHBondContact OG1-N 2.92Å; T454-D457 PolarHBondContact OG1-OD2 2.88Å; D457-G461 WeakPolarHBondContact O-CA 3.31Å; D457-G461 PolarHBondContact O-N 3.32Å; D457-R536 IonicContact OD1-NH1 3.39Å; D457-R536 PolarHBondContact OD1-NH1 3.03Å
458D94.6Very high94.9Very high3 Ų314.2 Ų14.22%0.0168%0.077CC..Hα-helixtrans-55.2-54.1169.1178.645.2000111.4R441 T454 C462 C624 R626 L627R441-D458 WeakPolarHBondContact CD-OD1 3.47Å; R441-D458 IonicContact NH1-OD2 3.34Å; R441-D458 PolarHBondContact NH1-OD2 2.86Å; T454-D458 PolarHBondContact O-N 2.81Å; D458-C462 VanDerWaalsContact O-CB 3.26Å; D458-C462 WeakPolarHBondContact O-CB 3.35Å; D458-C462 PolarHBondContact O-N 3.27Å; D458-C462 PolarHBondContact O-SG 3.19Å; D458-C624 HydrophobicContact CB-CB 4.3Å; D458-R626 IonicContact OD2-CZ 2.86Å; D458-R626 IonicContact OD2-NE 2.91Å; D458-R626 PolarHBondContact OD2-NE 2.84Å; D458-R626 IonicContact OD2-NH2 2.6Å; D458-R626 PolarHBondContact OD2-NH2 3.38Å; D458-L627 HydrophobicContact CB-CD1 3.98Å; D458-L627 HydrophobicContact CB-CD2 4.17Å; D458-L627 HydrophobicContact CB-CG 4.08Å; D458-L627 WeakPolarHBondContact OD1-CD2 3.2Å
459S94.6Very high95.1Very high6 Ų615.7 Ų15.74%0.0428%0.083CC..Hα-helixtrans-66.1-46.2-172.9-590000112.4V455 L456 A463V455-S459 WeakPolarHBondContact O-CB 3.44Å; V455-S459 PolarHBondContact O-N 3.49Å; V455-S459 PolarHBondContact O-OG 3.39Å; L456-S459 PolarHBondContact O-N 3.21Å; S459-A463 WeakPolarHBondContact O-CB 3.33Å; S459-A463 PolarHBondContact O-N 3.33Å
460I95.3Very high95.2Very high34 Ų3415.7 Ų15.717%0.1748%0.083CC..Hα-helixtrans-72.6-45.5178.7-62174.4000110.1L456 C462 A463 V464 R536L456-I460 HydrophobicContact CD1-CD1 3.56Å; L456-I460 HydrophobicContact CD1-CG1 4.08Å; L456-I460 HydrophobicContact CG-CD1 3.9Å; L456-I460 WeakPolarHBondContact O-CG1 3.35Å; L456-I460 PolarHBondContact O-N 3.25Å; I460-C462 VanDerWaalsContact C-N 3.34Å; I460-C462 PolarHBondContact O-N 3.48Å; I460-A463 PolarHBondContact O-N 3.18Å; I460-V464 HydrophobicContact CG2-CG2 3.99Å; I460-V464 WeakPolarHBondContact O-CG2 3.27Å; I460-V464 PolarHBondContact O-N 3.01Å; I460-R536 VanDerWaalsContact CG2-NH2 3.3Å
461G96.9Very high95.6Very high0 Ų018.3 Ų18.30%010%0.097CC..Hα-helixtrans-57.1-45.8-18000000112.2D457 W465D457-G461 WeakPolarHBondContact O-CA 3.31Å; D457-G461 PolarHBondContact O-N 3.32Å; G461-W465 VanDerWaalsContact O-CB 3.27Å; G461-W465 WeakPolarHBondContact O-CB 3.49Å; G461-W465 PolarHBondContact O-N 3.5Å
462C97.7Very high95.9Very high0 Ų017 Ų170%09%0.09CC..Hα-helixtrans-63.7-47.3175.4-70.30000112.2L437 I445 D458 I460 V464 W465 F466 I610L437-C462 HydrophobicContact CD1-CB 3.77Å; I445-C462 HydrophobicContact CD1-CB 4.37Å; D458-C462 VanDerWaalsContact O-CB 3.26Å; D458-C462 WeakPolarHBondContact O-CB 3.35Å; D458-C462 PolarHBondContact O-N 3.27Å; D458-C462 PolarHBondContact O-SG 3.19Å; I460-C462 VanDerWaalsContact C-N 3.34Å; I460-C462 PolarHBondContact O-N 3.48Å; C462-V464 VanDerWaalsContact C-N 3.34Å; C462-V464 PolarHBondContact O-N 2.96Å; C462-W465 PolarHBondContact O-N 3.48Å; C462-F466 VanDerWaalsContact O-CD2 3.25Å; C462-F466 WeakPolarHBondContact O-CD2 3.25Å; C462-F466 PolarHBondContact O-N 3.43Å; C462-I610 HydrophobicContact CB-CD1 3.47Å; C462-I610 VanDerWaalsContact CB-CD1 3.47Å
463A97.5Very high96.1Very high0 Ų021.4 Ų21.40%010%0.104CC..Hα-helixtrans-59.6-44.3179.900000112.2V354 F356 S459 I460 A467 M604V354-A463 HydrophobicContact CG1-CB 4.49Å; F356-A463 HydrophobicContact CE2-CB 4.01Å; F356-A463 HydrophobicContact CZ-CB 4.4Å; S459-A463 WeakPolarHBondContact O-CB 3.33Å; S459-A463 PolarHBondContact O-N 3.33Å; I460-A463 PolarHBondContact O-N 3.18Å; A463-A467 VanDerWaalsContact O-CB 3.25Å; A463-A467 WeakPolarHBondContact O-CB 3.35Å; A463-A467 PolarHBondContact O-N 2.96Å; A463-M604 HydrophobicContact CB-CG 4.06Å; A463-M604 HydrophobicContact CB-SD 3.74Å
464V98.2Very high96.2Very high5 Ų520.2 Ų20.23%0.0310%0.098CC..Hα-helixtrans-68.9-41.7178.8176.90000111.5L325 I460 C462 A467 S468 V540 I541 M604L325-V464 HydrophobicContact CD1-CG1 4.13Å; I460-V464 HydrophobicContact CG2-CG2 3.99Å; I460-V464 WeakPolarHBondContact O-CG2 3.27Å; I460-V464 PolarHBondContact O-N 3.01Å; C462-V464 VanDerWaalsContact C-N 3.34Å; C462-V464 PolarHBondContact O-N 2.96Å; V464-A467 PolarHBondContact O-N 3.46Å; V464-S468 WeakPolarHBondContact O-CB 3.45Å; V464-S468 PolarHBondContact O-N 2.92Å; V464-S468 PolarHBondContact O-OG 2.99Å; V464-V540 HydrophobicContact CB-CG2 3.97Å; V464-V540 HydrophobicContact CG1-CG2 3.65Å; V464-I541 HydrophobicContact CG1-CD1 3.74Å; V464-I541 HydrophobicContact CG1-CG1 3.53Å; V464-M604 HydrophobicContact CG2-CE 4.5Å; V464-M604 HydrophobicContact CG2-SD 3.95Å
465W98.4Very high95.9Very high13 Ų1323.7 Ų23.75%0.04912%0.119CC..Hα-helixtrans-58-54.5175.8-170.289.5000110.7L440 R444 I445 G461 C462 A467 S468 R469 V540 D543 H544L440-W465 HydrophobicContact CB-CZ3 4.42Å; L440-W465 HydrophobicContact CD1-CH2 3.87Å; L440-W465 HydrophobicContact CD1-CZ3 3.75Å; L440-W465 HydrophobicContact CD2-CH2 4.31Å; L440-W465 HydrophobicContact CG-CH2 4.47Å; R444-W465 HydrophobicContact CG-CZ2 3.94Å; I445-W465 HydrophobicContact CD1-CB 4.15Å; I445-W465 HydrophobicContact CD1-CD2 3.78Å; I445-W465 HydrophobicContact CD1-CE3 3.69Å; I445-W465 HydrophobicContact CD1-CG 4Å; I445-W465 HydrophobicContact CD1-CZ3 4.4Å; I445-W465 HydrophobicContact CG1-CB 4.31Å; I445-W465 HydrophobicContact CG1-CD2 3.69Å; I445-W465 HydrophobicContact CG1-CE3 4.07Å; I445-W465 HydrophobicContact CG1-CG 3.79Å; I445-W465 HydrophobicContact CG2-CB 4.37Å; I445-W465 HydrophobicContact CG2-CG 4.48Å; G461-W465 VanDerWaalsContact O-CB 3.27Å; G461-W465 WeakPolarHBondContact O-CB 3.49Å; G461-W465 PolarHBondContact O-N 3.5Å; C462-W465 PolarHBondContact O-N 3.48Å; W465-A467 VanDerWaalsContact C-N 3.35Å; W465-A467 PolarHBondContact O-N 3.4Å; W465-S468 PolarHBondContact O-N 3.4Å; W465-S468 PolarHBondContact O-OG 3.39Å; W465-S468 VanDerWaalsContact O-OG 3.05Å; W465-R469 PolarHBondContact O-N 2.92Å; W465-V540 HydrophobicContact CB-CB 3.97Å; W465-V540 HydrophobicContact CB-CG1 4.46Å; W465-V540 HydrophobicContact CG-CB 4.39Å; W465-D543 PolarHBondContact NE1-OD2 3.37Å; W465-H544 AromaticContact CD1-NE2 3.69Å; W465-H544 AromaticContact CD2-CE1 3.9Å; W465-H544 AromaticContact CD2-NE2 3.39Å; W465-H544 AromaticContact CE2-CE1 3.38Å; W465-H544 AromaticContact CE2-NE2 3.24Å; W465-H544 AromaticContact CE3-NE2 3.92Å; W465-H544 AromaticContact CG-NE2 3.71Å; W465-H544 AromaticContact CH2-CE1 3.73Å; W465-H544 AromaticContact CZ2-CE1 3.31Å; W465-H544 WeakPolarHBondContact CZ2-CE1 2.92Å; W465-H544 AromaticContact CZ2-NE2 3.69Å; W465-H544 AromaticContact NE1-CE1 3.78Å; W465-H544 AromaticContact NE1-NE2 3.43Å; W465-H544 PolarHBondContact NE1-NE2 3.17Å; W465-H544 PolarHBondContact O-NE2 3.49Å; W465-H544 VanDerWaalsContact O-NE2 3.11Å
466F98.5Very high95.2Very high0 Ų025.7 Ų25.70%014%0.137CC..Hα-helixtrans-61.9-41179.6-83.1-72.1000112.8V354 F356 V432 E436 L437 L440 I445 C462 R469V354-F466 HydrophobicContact CG2-CB 3.9Å; F356-F466 AromaticContact CE1-CD2 3.96Å; F356-F466 HydrophobicContact CE1-CD2 3.96Å; F356-F466 HydrophobicContact CE1-CE2 4.31Å; F356-F466 HydrophobicContact CZ-CB 4.47Å; F356-F466 AromaticContact CZ-CD2 3.95Å; F356-F466 HydrophobicContact CZ-CD2 3.95Å; F356-F466 HydrophobicContact CZ-CG 4.5Å; V432-F466 HydrophobicContact CB-CD1 4.41Å; V432-F466 HydrophobicContact CG1-CD1 3.95Å; V432-F466 HydrophobicContact CG1-CD2 4.12Å; V432-F466 HydrophobicContact CG1-CE1 3.66Å; V432-F466 HydrophobicContact CG1-CE2 3.87Å; V432-F466 HydrophobicContact CG1-CG 4.17Å; V432-F466 HydrophobicContact CG1-CZ 3.62Å; V432-F466 HydrophobicContact CG2-CB 3.84Å; V432-F466 HydrophobicContact CG2-CD1 3.51Å; V432-F466 HydrophobicContact CG2-CD2 4.25Å; V432-F466 HydrophobicContact CG2-CE1 4.08Å; V432-F466 HydrophobicContact CG2-CG 3.61Å; E436-F466 HydrophobicContact CG-CE1 3.85Å; E436-F466 HydrophobicContact CG-CZ 4.08Å; L437-F466 HydrophobicContact CB-CE2 4.47Å; L437-F466 HydrophobicContact CD1-CD2 4.49Å; L437-F466 HydrophobicContact CD1-CE2 3.76Å; L440-F466 HydrophobicContact CB-CZ 3.99Å; L440-F466 HydrophobicContact CD1-CE1 3.6Å; L440-F466 HydrophobicContact CD1-CZ 3.71Å; L440-F466 HydrophobicContact CG-CZ 4.43Å; I445-F466 HydrophobicContact CD1-CD2 4.25Å; I445-F466 HydrophobicContact CD1-CE2 3.79Å; I445-F466 HydrophobicContact CD1-CZ 4.45Å; C462-F466 VanDerWaalsContact O-CD2 3.25Å; C462-F466 WeakPolarHBondContact O-CD2 3.25Å; C462-F466 PolarHBondContact O-N 3.43Å; F466-R469 WeakPolarHBondContact O-CB 3.31Å
467A98.3Very high94.2Very high3 Ų332.7 Ų32.73%0.02517%0.168CC..Hα-helixtrans-62.2-47.917700000111.7L325 L352 V354 I430 A463 V464 W465 R469 G470L325-A467 HydrophobicContact CD2-CB 3.78Å; L352-A467 WeakPolarHBondContact CD1-O 3.44Å; V354-A467 HydrophobicContact CB-CB 3.95Å; V354-A467 HydrophobicContact CG1-CB 3.93Å; I430-A467 WeakPolarHBondContact CD1-O 3.46Å; A463-A467 VanDerWaalsContact O-CB 3.25Å; A463-A467 WeakPolarHBondContact O-CB 3.35Å; A463-A467 PolarHBondContact O-N 2.96Å; V464-A467 PolarHBondContact O-N 3.46Å; W465-A467 VanDerWaalsContact C-N 3.35Å; W465-A467 PolarHBondContact O-N 3.4Å; A467-R469 VanDerWaalsContact C-N 3.33Å; A467-R469 PolarHBondContact O-N 3.44Å; A467-G470 PolarHBondContact O-N 2.99Å
468S98.1Very high93.3Very high0 Ų040.5 Ų40.50%021%0.21CC..Hα-helixtrans-71-26.2-176.258.20000113.6V464 W465 G470 H544 K546V464-S468 WeakPolarHBondContact O-CB 3.45Å; V464-S468 PolarHBondContact O-N 2.92Å; V464-S468 PolarHBondContact O-OG 2.99Å; W465-S468 PolarHBondContact O-N 3.4Å; W465-S468 PolarHBondContact O-OG 3.39Å; W465-S468 VanDerWaalsContact O-OG 3.05Å; S468-G470 PolarHBondContact O-N 3.47Å; S468-H544 PolarHBondContact OG-CD2 3.48Å; S468-K546 VanDerWaalsContact O-CD 3.25Å; S468-K546 WeakPolarHBondContact O-CD 3.48Å; S468-K546 VanDerWaalsContact O-CE 3.31Å; S468-K546 WeakPolarHBondContact O-CE 3.34Å; S468-K546 PolarHBondContact O-NZ 3.47Å; S468-K546 VanDerWaalsContact O-NZ 3.09Å
469R97.9Very high92.8Very high34 Ų3442 Ų4213%0.12823%0.226CC..Hα-helixtrans-48.4-35.2168.7-170.7175.267.7177.3-0.2112.4E436 W465 F466 A467 I471 H544E436-R469 IonicContact OE1-CZ 2.92Å; E436-R469 IonicContact OE1-NH1 2.93Å; E436-R469 PolarHBondContact OE1-NH1 3.01Å; E436-R469 IonicContact OE1-NH2 3.51Å; E436-R469 PolarHBondContact OE1-NH2 3.33Å; E436-R469 IonicContact OE2-NH2 2.76Å; W465-R469 PolarHBondContact O-N 2.92Å; F466-R469 WeakPolarHBondContact O-CB 3.31Å; A467-R469 VanDerWaalsContact C-N 3.33Å; A467-R469 PolarHBondContact O-N 3.44Å; R469-I471 HydrophobicContact CG-CB 4.27Å; R469-I471 HydrophobicContact CG-CD1 3.77Å; R469-I471 HydrophobicContact CG-CG1 3.94Å; R469-I471 PolarHBondContact O-N 3.33Å; R469-H544 PolarHBondContact N-CD2 2.91Å
470G97.6Very high92.6Very high0 Ų046.1 Ų46.10%025%0.251CS..  trans65.322.2173.100000114.4A467 S468 H484 S485A467-G470 PolarHBondContact O-N 2.99Å; S468-G470 PolarHBondContact O-N 3.47Å; G470-H484 WeakPolarHBondContact O-CA 3.26Å; G470-S485 PolarHBondContact O-N 2.96Å
471I97.8Very high92.4Very high77 Ų7751.5 Ų51.540%0.39527%0.273SS..EExtended strand (participates in β ladder)trans-101.9117.9174.3-62.3172.3000107.8R469 Y483 H484R469-I471 HydrophobicContact CG-CB 4.27Å; R469-I471 HydrophobicContact CG-CD1 3.77Å; R469-I471 HydrophobicContact CG-CG1 3.94Å; R469-I471 PolarHBondContact O-N 3.33Å; I471-Y483 WeakPolarHBondContact CA-O 3.25Å; I471-H484 HydrophobicContact CG1-CB 4.39Å; I471-H484 VanDerWaalsContact CG1-CD2 3.45Å; I471-H484 WeakPolarHBondContact CG1-CD2 3.46Å
472G96.6Very high92.3Very high6 Ų655.5 Ų55.56%0.06230%0.301CS..EExtended strand (participates in β ladder)trans-170.4-148.6-177.400000112E429 Y483E429-G472 CarbonylContact O-C 3.56Å; E429-G472 VanDerWaalsContact O-CA 3.25Å; E429-G472 WeakPolarHBondContact O-CA 3.49Å; G472-Y483 PolarHBondContact N-O 2.91Å; G472-Y483 PolarHBondContact O-N 3.46Å
473W95.4Very high92.2Very high120 Ų12057.6 Ų57.646%0.45531%0.309SS..EExtended strand (participates in β ladder)trans-124.5139.4-174.2-5492.3000111.5E429 V480 K481E429-W473 HydrophobicContact CB-CB 4.43Å; E429-W473 WeakPolarHBondContact CB-O 3.47Å; E429-W473 PolarHBondContact N-O 3.11Å; E429-W473 PolarHBondContact O-N 3.19Å; W473-V480 HydrophobicContact CB-CG1 3.74Å; W473-V480 HydrophobicContact CD2-CG1 4.18Å; W473-V480 HydrophobicContact CE3-CG1 3.82Å; W473-V480 HydrophobicContact CG-CG1 4.19Å; W473-K481 CarbonylContact C-O 3.59Å; W473-K481 WeakPolarHBondContact CA-O 3.48Å
474L94.1Very high92.2Very high30 Ų3063.6 Ų63.616%0.15734%0.337CS..EExtended strand (participates in β ladder)trans-98.7130.2166.3-67178.9000109N426 F427 V428 V480 K481 Y483N426-L474 HydrophobicContact CB-CD2 4.03Å; F427-L474 WeakPolarHBondContact O-CD2 3.32Å; V428-L474 HydrophobicContact CG2-CD2 4.06Å; L474-V480 WeakPolarHBondContact O-CA 3.49Å; L474-K481 PolarHBondContact N-O 3.4Å; L474-K481 PolarHBondContact O-N 3.33Å; L474-Y483 HydrophobicContact CD1-CD1 4.36Å; L474-Y483 HydrophobicContact CD1-CD2 3.39Å; L474-Y483 HydrophobicContact CD1-CE2 3.89Å; L474-Y483 HydrophobicContact CD1-CG 3.66Å; L474-Y483 HydrophobicContact CD2-CD1 4.41Å; L474-Y483 HydrophobicContact CD2-CG 4.35Å; L474-Y483 HydrophobicContact CG-CD1 4.3Å; L474-Y483 HydrophobicContact CG-CD2 4.05Å; L474-Y483 HydrophobicContact CG-CG 3.76Å
475V87.3Confident92.1Very high91 Ų9163.4 Ų63.455%0.55234%0.336SS*.EExtended strand (participates in β ladder)trans-95.9105.9172.5-1750000107.9E429E429-V475 HydrophobicContact CG-CG2 4.39Å
476A77.6Confident91.9Very high59 Ų5965.4 Ų65.449%0.48835%0.352SS..EExtended strand (participates in β ladder)trans-109.7169.6175.900000110.6D478 G479A476-D478 PolarHBondContact O-N 2.95Å; A476-G479 PolarHBondContact N-O 3.05Å; A476-G479 PolarHBondContact O-N 3.32Å
477Q71.4Confident91.8Very high202 Ų20265.4 Ų65.494%0.94435%0.352SS*.THydrogen-bonded Turntrans-60-32.4176.1-69.8178-11.100111.9G479Q477-G479 VanDerWaalsContact C-N 3.29Å; Q477-G479 PolarHBondContact O-N 3.35Å
478D74.8Confident91.6Very high167 Ų16768.7 Ų68.789%0.89337%0.365SS*.THydrogen-bonded Turntrans-87.77.5-178.7-52.8-36.9000113.7A476A476-D478 PolarHBondContact O-N 2.95Å
479G85.2Confident91.6Very high34 Ų3468.8 Ų68.835%0.35137%0.366SS..EExtended strand (participates in β ladder)trans121.1-168.5177.400000114.7A476 Q477A476-G479 PolarHBondContact N-O 3.05Å; A476-G479 PolarHBondContact O-N 3.32Å; Q477-G479 VanDerWaalsContact C-N 3.29Å; Q477-G479 PolarHBondContact O-N 3.35Å
480V89.3Confident91.6Very high93 Ų9367.1 Ų67.156%0.56436%0.36SS*.EExtended strand (participates in β ladder)trans-98.2124.8-177.4-174.70000109.8W473 L474W473-V480 HydrophobicContact CB-CG1 3.74Å; W473-V480 HydrophobicContact CD2-CG1 4.18Å; W473-V480 HydrophobicContact CE3-CG1 3.82Å; W473-V480 HydrophobicContact CG-CG1 4.19Å; L474-V480 WeakPolarHBondContact O-CA 3.49Å
481K92.3Very high91.7Very high148 Ų14867.1 Ų67.164%0.64336%0.36SS*.EExtended strand (participates in β ladder)trans-119136.7-178.7-172.7-177.1174.1-179.60110.8W473 L474W473-K481 CarbonylContact C-O 3.59Å; W473-K481 WeakPolarHBondContact CA-O 3.48Å; L474-K481 PolarHBondContact N-O 3.4Å; L474-K481 PolarHBondContact O-N 3.33Å
482S94.8Very high91.7Very high83 Ų8363.5 Ų63.558%0.5834%0.341SS*.EExtended strand (participates in β ladder)trans-66.2142.6171.483.30000110.3
483Y95.9Very high91.7Very high45 Ų4564 Ų6418%0.17635%0.347CS..EExtended strand (participates in β ladder)trans-143.3141.1-175-174.8-99.4000111.2D350 N426 V428 I471 G472 L474D350-Y483 PolarHBondContact OD1-OH 2.76Å; D350-Y483 WeakPolarHBondContact OD2-CE1 3.47Å; D350-Y483 PolarHBondContact OD2-OH 3.09Å; N426-Y483 PolarHBondContact ND2-OH 3.28Å; V428-Y483 HydrophobicContact CB-CD1 4.46Å; V428-Y483 HydrophobicContact CG1-CD1 4.06Å; V428-Y483 HydrophobicContact CG2-CD1 3.53Å; V428-Y483 HydrophobicContact CG2-CE1 3.66Å; I471-Y483 WeakPolarHBondContact CA-O 3.25Å; G472-Y483 PolarHBondContact N-O 2.91Å; G472-Y483 PolarHBondContact O-N 3.46Å; L474-Y483 HydrophobicContact CD1-CD1 4.36Å; L474-Y483 HydrophobicContact CD1-CD2 3.39Å; L474-Y483 HydrophobicContact CD1-CE2 3.89Å; L474-Y483 HydrophobicContact CD1-CG 3.66Å; L474-Y483 HydrophobicContact CD2-CD1 4.41Å; L474-Y483 HydrophobicContact CD2-CG 4.35Å; L474-Y483 HydrophobicContact CG-CD1 4.3Å; L474-Y483 HydrophobicContact CG-CD2 4.05Å; L474-Y483 HydrophobicContact CG-CG 3.76Å
484H96.6Very high91.7Very high125 Ų12559.8 Ų59.858%0.57933%0.332SS*.EExtended strand (participates in β ladder)trans-126.6111.9172.9-178.4-161.1000108.5G470 I471 S486G470-H484 WeakPolarHBondContact O-CA 3.26Å; I471-H484 HydrophobicContact CG1-CB 4.39Å; I471-H484 VanDerWaalsContact CG1-CD2 3.45Å; I471-H484 WeakPolarHBondContact CG1-CD2 3.46Å; H484-S486 PolarHBondContact O-N 3.14Å
485S96.5Very high91.8Very high1 Ų158.3 Ų58.31%0.00733%0.325CS..  trans-64.9116.6177.9176.50000110.9D350 G470 A487 K546D350-S485 WeakPolarHBondContact OD2-CA 3.22Å; D350-S485 WeakPolarHBondContact OD2-CB 3.35Å; D350-S485 PolarHBondContact OD2-OG 3.4Å; G470-S485 PolarHBondContact O-N 2.96Å; S485-A487 VanDerWaalsContact C-N 3.26Å; S485-A487 PolarHBondContact OG-N 3.07Å; S485-K546 PolarHBondContact O-NZ 3.11Å; S485-K546 VanDerWaalsContact O-NZ 3.17Å
486S94Very high92.3Very high55 Ų5554 Ų5439%0.38530%0.298SS..  trans-80.5-4.3173.856.60000114K319 A320 H484 K488K319-S486 WeakPolarHBondContact CB-OG 3.25Å; A320-S486 PolarHBondContact O-OG 3.3Å; H484-S486 PolarHBondContact O-N 3.14Å; S486-K488 PolarHBondContact O-N 2.82Å
487A96.1Very high93.3Very high0 Ų051.8 Ų51.80%028%0.278CS..  trans-60.2121.8-177.700000110.4A320 A323 S485 K546A320-A487 WeakPolarHBondContact O-CA 3.47Å; A320-A487 PolarHBondContact O-N 3.07Å; A323-A487 HydrophobicContact CB-CB 3.66Å; S485-A487 VanDerWaalsContact C-N 3.26Å; S485-A487 PolarHBondContact OG-N 3.07Å; A487-K546 VanDerWaalsContact O-CD 3.23Å; A487-K546 WeakPolarHBondContact O-CD 3.04Å; A487-K546 WeakPolarHBondContact O-CE 3.33Å
488K95.3Very high94.5Very high73 Ų7342.3 Ų42.332%0.31723%0.234SC..SBendtrans-83.9-16.3174.8-65.5-179.7178.3-176.60112.2N33 L54 H55 L56 S486 K546 E547N33-K488 PolarHBondContact OD1-NZ 2.65Å; L54-K488 HydrophobicContact CD1-CD 3.94Å; L54-K488 HydrophobicContact CD1-CG 4.3Å; H55-K488 PolarHBondContact O-NZ 3.03Å; L56-K488 HydrophobicContact CD2-CB 3.74Å; L56-K488 HydrophobicContact CD2-CD 4.18Å; S486-K488 PolarHBondContact O-N 2.82Å; K488-K546 CarbonylContact O-C 3.53Å; K488-K546 VanDerWaalsContact O-CA 3.29Å; K488-K546 WeakPolarHBondContact O-CA 3.42Å; K488-E547 PolarHBondContact O-N 2.92Å
489V97.6Very high95.6Very high1 Ų134.5 Ų34.51%0.00619%0.192CC..EExtended strand (participates in β ladder)trans-110.2131.7178.4169.40000110.2L56 L301 N321 A323 L491 R549L56-V489 HydrophobicContact CD2-CG2 4.15Å; L301-V489 HydrophobicContact CD1-CB 4.43Å; L301-V489 HydrophobicContact CD1-CG2 4.27Å; L301-V489 HydrophobicContact CD2-CG2 3.55Å; N321-V489 PolarHBondContact O-N 3.05Å; A323-V489 PolarHBondContact N-O 3.02Å; V489-L491 HydrophobicContact CG1-CD2 4.19Å; V489-R549 HydrophobicContact CG1-CG 3.98Å
490V98.4Very high96.2Very high0 Ų032.9 Ų32.90%018%0.175CC..EExtended strand (participates in β ladder)trans-122110.8177.6-176.40000109.1A323 L325 T492 I541 K546 E547 A548 R549A323-V490 HydrophobicContact CB-CG2 4.39Å; A323-V490 CarbonylContact O-C 3.6Å; A323-V490 VanDerWaalsContact O-CA 3.32Å; A323-V490 WeakPolarHBondContact O-CA 3.44Å; L325-V490 HydrophobicContact CD1-CG1 4.4Å; L325-V490 HydrophobicContact CD2-CG1 3.78Å; L325-V490 HydrophobicContact CG-CG1 3.58Å; V490-T492 HydrophobicContact CG1-CG2 4.5Å; V490-I541 HydrophobicContact CB-CG2 4.46Å; V490-I541 HydrophobicContact CG2-CG2 4.4Å; V490-K546 HydrophobicContact CG2-CB 4.03Å; V490-K546 HydrophobicContact CG2-CD 3.79Å; V490-E547 PolarHBondContact N-O 3.4Å; V490-A548 CarbonylContact O-C 3.56Å; V490-A548 WeakPolarHBondContact O-CA 3.3Å; V490-R549 PolarHBondContact O-N 3.08Å
491L98.8Very high96.6Very high0 Ų028.4 Ų28.40%015%0.149CC..EExtended strand (participates in β ladder)trans-75.8138.3171.4-53.9-175.6000109.9V294 R297 V298 V322 A323 I324 L325 I335 A339 V489 R549V294-L491 HydrophobicContact CG1-CD1 4.45Å; R297-L491 HydrophobicContact CB-CD2 4.14Å; V298-L491 HydrophobicContact CG1-CD1 4.03Å; V298-L491 HydrophobicContact CG1-CD2 4.35Å; V322-L491 HydrophobicContact CG1-CD1 4.05Å; V322-L491 HydrophobicContact CG1-CG 3.9Å; A323-L491 PolarHBondContact O-N 3.48Å; I324-L491 HydrophobicContact CG1-CB 4.24Å; I324-L491 HydrophobicContact CG1-CD1 4.38Å; L325-L491 PolarHBondContact N-O 3.47Å; I335-L491 HydrophobicContact CG2-CB 3.78Å; I335-L491 HydrophobicContact CG2-CD1 3.72Å; I335-L491 HydrophobicContact CG2-CG 4.41Å; A339-L491 HydrophobicContact CB-CD1 3.98Å; V489-L491 HydrophobicContact CG1-CD2 4.19Å; L491-R549 HydrophobicContact CD2-CB 3.85Å
492T97.6Very high96.8Very high1 Ų121.5 Ų21.51%0.00612%0.119CC..  trans-126.3147.9179.877.40000111.3L325 I335 V490 I494 I541 A548 R549 F550 P551L325-T492 HydrophobicContact CD1-CG2 3.91Å; L325-T492 HydrophobicContact CG-CG2 4.33Å; I335-T492 WeakPolarHBondContact CD1-O 3.32Å; V490-T492 HydrophobicContact CG1-CG2 4.5Å; T492-I494 PolarHBondContact O-N 2.86Å; T492-I541 HydrophobicContact CG2-CD1 4.22Å; T492-A548 HydrophobicContact CG2-CB 4.37Å; T492-R549 PolarHBondContact N-O 3.13Å; T492-F550 WeakPolarHBondContact OG1-CD1 3.41Å; T492-P551 WeakPolarHBondContact O-CD 3.34Å
493G97.1Very high96.8Very high17 Ų1719.7 Ų19.718%0.17510%0.1CC..  trans-81.98.4173.600000114.8A496G493-A496 WeakPolarHBondContact O-CB 3.39Å; G493-A496 PolarHBondContact O-N 3.29Å
494I95.4Very high96.6Very high30 Ų3021.8 Ų21.815%0.15412%0.121CC..THydrogen-bonded Turntrans-63.6138.7-177.9-65.5163.7000109.6T492 L534 D537 F550 L553T492-I494 PolarHBondContact O-N 2.86Å; I494-L534 HydrophobicContact CG2-CD2 3.89Å; I494-D537 HydrophobicContact CD1-CB 4.19Å; I494-D537 WeakPolarHBondContact CD1-OD2 2.93Å; I494-F550 HydrophobicContact CB-CD1 4.11Å; I494-F550 HydrophobicContact CB-CE1 4.4Å; I494-F550 HydrophobicContact CD1-CE1 4.02Å; I494-F550 HydrophobicContact CG2-CD1 4.44Å; I494-L553 HydrophobicContact CG2-CD1 4.49Å
495G96.4Very high96.5Very high0 Ų019.6 Ų19.60%011%0.108CC..THydrogen-bonded Turntrans99.5-20.9-175.900000113.6E498 Q499G495-E498 VanDerWaalsContact C-OE2 3.32Å; G495-E498 WeakPolarHBondContact CA-OE2 3.43Å; G495-E498 PolarHBondContact N-OE2 3.13Å; G495-E498 VanDerWaalsContact N-OE2 3.13Å; G495-Q499 WeakPolarHBondContact O-CB 3.44Å; G495-Q499 WeakPolarHBondContact O-CG 3.3Å; G495-Q499 PolarHBondContact O-N 2.97Å; G495-Q499 PolarHBondContact O-NE2 3.18Å
496A97.9Very high96.5Very high0 Ų019.6 Ų19.60%011%0.107CC..Hα-helixtrans-67.1-45.7179.100000111.9D331 G493 L500 F552 L584D331-A496 HydrophobicContact CB-CB 4.21Å; G493-A496 WeakPolarHBondContact O-CB 3.39Å; G493-A496 PolarHBondContact O-N 3.29Å; A496-L500 VanDerWaalsContact O-CB 3.22Å; A496-L500 WeakPolarHBondContact O-CB 3.19Å; A496-L500 PolarHBondContact O-N 3.43Å; A496-F552 HydrophobicContact CB-CD1 3.96Å; A496-F552 HydrophobicContact CB-CD2 3.77Å; A496-F552 HydrophobicContact CB-CE1 4.01Å; A496-F552 HydrophobicContact CB-CE2 3.82Å; A496-F552 HydrophobicContact CB-CG 3.84Å; A496-F552 HydrophobicContact CB-CZ 3.94Å; A496-L584 HydrophobicContact CB-CD2 4.5Å
497D97.3Very high96.5Very high12 Ų1218.7 Ų18.76%0.06410%0.096CC..Hα-helixtrans-65.9-42.1-178.4-76.9-77000113.2Q499 A501 G502 Y503 H506 K581 K601D497-Q499 VanDerWaalsContact C-N 3.31Å; D497-Q499 PolarHBondContact O-N 3.4Å; D497-A501 PolarHBondContact O-N 2.93Å; D497-G502 PolarHBondContact O-N 3.47Å; D497-G502 VanDerWaalsContact OD1-CA 3.32Å; D497-G502 WeakPolarHBondContact OD1-CA 2.86Å; D497-Y503 HydrophobicContact CB-CD1 4.37Å; D497-Y503 HydrophobicContact CB-CD2 4.02Å; D497-Y503 HydrophobicContact CB-CE1 3.94Å; D497-Y503 HydrophobicContact CB-CE2 3.55Å; D497-Y503 HydrophobicContact CB-CG 4.39Å; D497-Y503 VanDerWaalsContact CB-CZ 3.49Å; D497-H506 PolarHBondContact O-CE1 3.17Å; D497-H506 VanDerWaalsContact O-CE1 3.32Å; D497-K581 WeakPolarHBondContact OD1-CE 3.15Å; D497-K581 IonicContact OD1-NZ 2.72Å; D497-K581 PolarHBondContact OD1-NZ 2.61Å; D497-K581 IonicContact OD2-NZ 3.21Å; D497-K581 PolarHBondContact OD2-NZ 3.4Å; D497-K581 VanDerWaalsContact OD2-NZ 3.13Å; D497-K601 VanDerWaalsContact OD1-CD 3.24Å; D497-K601 WeakPolarHBondContact OD1-CD 3.46Å; D497-K601 WeakPolarHBondContact OD1-CE 3.46Å; D497-K601 IonicContact OD1-NZ 3.61Å; D497-K601 PolarHBondContact OD1-NZ 3.13Å; D497-K601 IonicContact OD2-NZ 3.37Å; D497-K601 PolarHBondContact OD2-NZ 3.04Å
498E96.6Very high96.5Very high3 Ų322.7 Ų22.71%0.01412%0.12CC..Hα-helixtrans-63.9-36.5-179.1-6673.2-160.200111.4G495 Y503 I522 E525 L526 I529G495-E498 VanDerWaalsContact C-OE2 3.32Å; G495-E498 WeakPolarHBondContact CA-OE2 3.43Å; G495-E498 PolarHBondContact N-OE2 3.13Å; G495-E498 VanDerWaalsContact N-OE2 3.13Å; E498-Y503 HydrophobicContact CG-CE2 4.13Å; E498-Y503 WeakPolarHBondContact OE1-CE2 3.02Å; E498-Y503 PolarHBondContact OE1-OH 3Å; E498-I522 WeakPolarHBondContact O-CD1 3.39Å; E498-I522 WeakPolarHBondContact O-CG2 3.47Å; E498-E525 HydrophobicContact CB-CB 4.25Å; E498-E525 HydrophobicContact CG-CB 4.18Å; E498-L526 HydrophobicContact CB-CD2 3.92Å; E498-I529 HydrophobicContact CG-CD1 4.06Å; E498-I529 HydrophobicContact CG-CG1 4.49Å
499Q97.9Very high96.5Very high3 Ų324.5 Ų24.51%0.01412%0.124CC..Hα-helixtrans-91.6-30.5-176.6-66.7176.388.700113.9G495 D497 L526 F552 L561G495-Q499 WeakPolarHBondContact O-CB 3.44Å; G495-Q499 WeakPolarHBondContact O-CG 3.3Å; G495-Q499 PolarHBondContact O-N 2.97Å; G495-Q499 PolarHBondContact O-NE2 3.18Å; D497-Q499 VanDerWaalsContact C-N 3.31Å; D497-Q499 PolarHBondContact O-N 3.4Å; Q499-L526 HydrophobicContact CG-CD2 3.58Å; Q499-F552 PolarHBondContact NE2-O 2.99Å; Q499-L561 HydrophobicContact CB-CD1 3.9Å; Q499-L561 HydrophobicContact CG-CD1 4.47Å
500L98.3Very high96.5Very high0 Ų026.3 Ų26.30%013%0.132CC..THydrogen-bonded Turntrans-110.423.7-170.8-59.2170.5000113.1F286 A496 G502 L561 K569 K581 L583 L584F286-L500 HydrophobicContact CZ-CD1 4.34Å; A496-L500 VanDerWaalsContact O-CB 3.22Å; A496-L500 WeakPolarHBondContact O-CB 3.19Å; A496-L500 PolarHBondContact O-N 3.43Å; L500-G502 PolarHBondContact O-N 2.99Å; L500-L561 HydrophobicContact CD2-CD1 4.19Å; L500-L561 HydrophobicContact CD2-CD2 3.66Å; L500-L561 HydrophobicContact CG-CD1 4.42Å; L500-K569 HydrophobicContact CD2-CB 4.06Å; L500-K569 HydrophobicContact CD2-CG 4.35Å; L500-K581 HydrophobicContact CB-CB 4.08Å; L500-K581 HydrophobicContact CB-CG 3.99Å; L500-K581 VanDerWaalsContact O-CA 3.25Å; L500-K581 WeakPolarHBondContact O-CA 3.24Å; L500-K581 PolarHBondContact O-N 3.02Å; L500-L583 HydrophobicContact CD2-CB 4.46Å; L500-L583 HydrophobicContact CD2-CD2 4.39Å; L500-L584 HydrophobicContact CD1-CB 3.73Å; L500-L584 HydrophobicContact CD1-CD2 4.09Å; L500-L584 HydrophobicContact CD1-CG 4.45Å
501A97.8Very high96.3Very high0 Ų032.8 Ų32.80%016%0.163CC..THydrogen-bonded Turntrans53.446.4179.400000114.1D497 H506 L518 I522 A570 L572D497-A501 PolarHBondContact O-N 2.93Å; A501-H506 WeakPolarHBondContact CA-ND1 2.88Å; A501-H506 HydrophobicContact CB-CB 4.19Å; A501-L518 HydrophobicContact CB-CD1 4.08Å; A501-L518 HydrophobicContact CB-CD2 4.48Å; A501-I522 HydrophobicContact CB-CD1 4.13Å; A501-A570 HydrophobicContact CB-CB 3.69Å; A501-L572 HydrophobicContact CB-CD1 4.43Å
502G96.6Very high96.2Very high2 Ų236.7 Ų36.72%0.02119%0.19CC..  trans-78.1-31.8-174.300000116.5D497 L500 H506 K581 K601D497-G502 PolarHBondContact O-N 3.47Å; D497-G502 VanDerWaalsContact OD1-CA 3.32Å; D497-G502 WeakPolarHBondContact OD1-CA 2.86Å; L500-G502 PolarHBondContact O-N 2.99Å; G502-H506 PolarHBondContact N-ND1 3.33Å; G502-K581 VanDerWaalsContact CA-CE 3.49Å; G502-K601 WeakPolarHBondContact O-CD 3.23Å
503Y94.7Very high96.1Very high46 Ų4642 Ų4218%0.1821%0.214CC..SBendtrans-71.6145.5-176.8-62.6-62.9000113.5D497 E498 R505 H506 K601D497-Y503 HydrophobicContact CB-CD1 4.37Å; D497-Y503 HydrophobicContact CB-CD2 4.02Å; D497-Y503 HydrophobicContact CB-CE1 3.94Å; D497-Y503 HydrophobicContact CB-CE2 3.55Å; D497-Y503 HydrophobicContact CB-CG 4.39Å; D497-Y503 VanDerWaalsContact CB-CZ 3.49Å; E498-Y503 HydrophobicContact CG-CE2 4.13Å; E498-Y503 WeakPolarHBondContact OE1-CE2 3.02Å; E498-Y503 PolarHBondContact OE1-OH 3Å; Y503-R505 PolarHBondContact O-N 2.99Å; Y503-H506 AromaticContact CD2-CE1 3.36Å; Y503-H506 WeakPolarHBondContact CD2-CE1 3.22Å; Y503-H506 AromaticContact CD2-NE2 3.67Å; Y503-H506 AromaticContact CG-CE1 3.95Å; Y503-H506 PolarHBondContact N-ND1 3.42Å; Y503-H506 VanDerWaalsContact O-CB 3.23Å; Y503-H506 WeakPolarHBondContact O-CB 3.36Å; Y503-H506 PolarHBondContact O-N 3.41Å; Y503-K601 HydrophobicContact CD1-CD 4.32Å
504S92.2Very high96Very high88 Ų8842.6 Ų42.662%0.61522%0.221SC*.Hα-helixtrans-57.6-33.2175.753.10000113H506 R507 V508S504-H506 PolarHBondContact O-N 3.38Å; S504-R507 WeakPolarHBondContact O-CB 3.34Å; S504-R507 PolarHBondContact O-N 3.31Å; S504-R507 VanDerWaalsContact O-N 3.17Å; S504-V508 PolarHBondContact O-N 2.9Å
505R93.4Very high96Very high80 Ų8042.8 Ų42.830%0.30222%0.222SC..Hα-helixtrans-60.3-29.4175.170.3-176168-148.7-7.4113.2Y503 R507 V508 R509 E521 E525 R528Y503-R505 PolarHBondContact O-N 2.99Å; R505-R507 VanDerWaalsContact C-N 3.33Å; R505-V508 PolarHBondContact O-N 3.08Å; R505-R509 WeakPolarHBondContact O-CG 3.46Å; R505-R509 PolarHBondContact O-N 2.87Å; R505-E521 WeakPolarHBondContact CD-OE1 3.44Å; R505-E521 IonicContact NE-OE1 2.65Å; R505-E525 IonicContact CZ-OE1 3.31Å; R505-E525 IonicContact CZ-OE2 3.78Å; R505-E525 IonicContact NE-OE1 3.96Å; R505-E525 PolarHBondContact NE-OE1 3.23Å; R505-E525 IonicContact NH1-OE1 2.72Å; R505-E525 PolarHBondContact NH1-OE1 3.38Å; R505-E525 IonicContact NH1-OE2 2.61Å; R505-E525 IonicContact NH2-OE1 3.48Å; R505-E525 PolarHBondContact NH2-OE1 3.38Å; R505-E525 IonicContact NH2-OE2 3.54Å; R505-E525 PolarHBondContact NH2-OE2 3.09Å; R505-R528 VanDerWaalsContact NH1-NH2 3.13Å
506H96.7Very high95.9Very high0 Ų047.5 Ų47.50%024%0.244CC..Hα-helixtrans-64.7-41.5177.1-58.8152.4000111D497 A501 G502 Y503 S504 R509 F510 L518 L572D497-H506 PolarHBondContact O-CE1 3.17Å; D497-H506 VanDerWaalsContact O-CE1 3.32Å; A501-H506 WeakPolarHBondContact CA-ND1 2.88Å; A501-H506 HydrophobicContact CB-CB 4.19Å; G502-H506 PolarHBondContact N-ND1 3.33Å; Y503-H506 AromaticContact CD2-CE1 3.36Å; Y503-H506 WeakPolarHBondContact CD2-CE1 3.22Å; Y503-H506 AromaticContact CD2-NE2 3.67Å; Y503-H506 AromaticContact CG-CE1 3.95Å; Y503-H506 PolarHBondContact N-ND1 3.42Å; Y503-H506 VanDerWaalsContact O-CB 3.23Å; Y503-H506 WeakPolarHBondContact O-CB 3.36Å; Y503-H506 PolarHBondContact O-N 3.41Å; S504-H506 PolarHBondContact O-N 3.38Å; H506-R509 PolarHBondContact O-N 2.93Å; H506-F510 WeakPolarHBondContact O-CB 3.18Å; H506-F510 PolarHBondContact O-N 3.32Å; H506-L518 HydrophobicContact CB-CD1 3.65Å; H506-L572 HydrophobicContact CB-CD1 4.3Å
507R94.9Very high95.8Very high37 Ų3748 Ų4814%0.1425%0.25CC..Hα-helixtrans-63.2-43.8173.3-175.9177.2-68.8-91.28.3111.6S504 R505 R509 F510 Q511 L572 L574 P575 E580S504-R507 WeakPolarHBondContact O-CB 3.34Å; S504-R507 PolarHBondContact O-N 3.31Å; S504-R507 VanDerWaalsContact O-N 3.17Å; R505-R507 VanDerWaalsContact C-N 3.33Å; R507-R509 VanDerWaalsContact C-N 3.35Å; R507-R509 PolarHBondContact O-N 3.36Å; R507-F510 PolarHBondContact O-N 3.06Å; R507-Q511 HydrophobicContact CG-CG 4.43Å; R507-Q511 WeakPolarHBondContact O-CB 3.5Å; R507-Q511 VanDerWaalsContact O-CG 3.26Å; R507-Q511 WeakPolarHBondContact O-CG 3.41Å; R507-Q511 PolarHBondContact O-N 3.46Å; R507-L572 HydrophobicContact CB-CD1 4.46Å; R507-L572 PolarHBondContact NH1-O 3.15Å; R507-L574 PolarHBondContact NH1-O 3.27Å; R507-L574 PolarHBondContact NH2-O 3.39Å; R507-P575 PolarHBondContact NH2-O 3.46Å; R507-E580 IonicContact CZ-OE1 2.82Å; R507-E580 IonicContact NE-OE1 2.82Å; R507-E580 PolarHBondContact NE-OE1 2.81Å; R507-E580 IonicContact NH2-OE1 2.79Å; R507-E580 PolarHBondContact NH2-OE1 3.3Å; R507-E580 IonicContact NH2-OE2 3.22Å; R507-E580 PolarHBondContact NH2-OE2 3.11Å; R507-E580 VanDerWaalsContact NH2-OE2 3.16Å
508V95.3Very high95.8Very high83 Ų8347.5 Ų47.550%0.50325%0.247SC..Hα-helixtrans-58.8-47175.4176.90000110.7S504 R505 F510 Q511 S512S504-V508 PolarHBondContact O-N 2.9Å; R505-V508 PolarHBondContact O-N 3.08Å; V508-F510 PolarHBondContact O-N 3.15Å; V508-Q511 PolarHBondContact O-N 3.16Å; V508-S512 PolarHBondContact O-N 3.41Å; V508-S512 PolarHBondContact O-OG 3.26Å; V508-S512 VanDerWaalsContact O-OG 3.14Å
509R96.1Very high95.8Very high111 Ų11147.6 Ų47.642%0.41925%0.247SC..Hα-helixtrans-62.1-43.6177.5-73.4-63.8-165.4-165.6-2.2112.8R505 H506 R507 S512 H513 E521R505-R509 WeakPolarHBondContact O-CG 3.46Å; R505-R509 PolarHBondContact O-N 2.87Å; H506-R509 PolarHBondContact O-N 2.93Å; R507-R509 VanDerWaalsContact C-N 3.35Å; R507-R509 PolarHBondContact O-N 3.36Å; R509-S512 PolarHBondContact O-N 3.33Å; R509-H513 PolarHBondContact O-N 3.49Å; R509-E521 HydrophobicContact CB-CB 4.39Å; R509-E521 HydrophobicContact CG-CB 4.05Å; R509-E521 HydrophobicContact CG-CG 3.89Å; R509-E521 WeakPolarHBondContact CG-OE2 3.22Å; R509-E521 IonicContact CZ-OE2 3.63Å; R509-E521 IonicContact NE-OE2 3.63Å; R509-E521 PolarHBondContact NE-OE2 2.81Å; R509-E521 IonicContact NH2-OE2 3.86Å
510F96.3Very high95.7Very high39 Ų3953.1 Ų53.117%0.17127%0.271CS..Hα-helixtrans-61.3-43.9175.2172.7-99000112.3H506 R507 V508 S512 G514 L515 L518 L572 T573H506-F510 WeakPolarHBondContact O-CB 3.18Å; H506-F510 PolarHBondContact O-N 3.32Å; R507-F510 PolarHBondContact O-N 3.06Å; V508-F510 PolarHBondContact O-N 3.15Å; F510-S512 VanDerWaalsContact C-N 3.29Å; F510-S512 PolarHBondContact O-N 3.26Å; F510-G514 WeakPolarHBondContact O-CA 3.49Å; F510-G514 PolarHBondContact O-N 2.7Å; F510-L515 HydrophobicContact CD2-CD2 4.05Å; F510-L515 HydrophobicContact CE2-CD2 3.66Å; F510-L515 HydrophobicContact CE2-CG 4.07Å; F510-L518 HydrophobicContact CB-CB 4.4Å; F510-L518 HydrophobicContact CD2-CD2 4.41Å; F510-L572 HydrophobicContact CB-CB 4.28Å; F510-L572 HydrophobicContact CB-CD1 3.78Å; F510-L572 HydrophobicContact CD1-CB 3.54Å; F510-L572 HydrophobicContact CE1-CB 3.96Å; F510-L572 HydrophobicContact CG-CB 3.85Å; F510-L572 HydrophobicContact CG-CD1 4.17Å; F510-T573 HydrophobicContact CE1-CG2 3.94Å; F510-T573 HydrophobicContact CZ-CG2 3.76Å
511Q95.1Very high95.6Very high137 Ų13754 Ų5464%0.6428%0.275SS*.Hα-helixtrans-63.6-36.2177.4-74.1170.5-28.600112.2R507 V508R507-Q511 HydrophobicContact CG-CG 4.43Å; R507-Q511 WeakPolarHBondContact O-CB 3.5Å; R507-Q511 VanDerWaalsContact O-CG 3.26Å; R507-Q511 WeakPolarHBondContact O-CG 3.41Å; R507-Q511 PolarHBondContact O-N 3.46Å; V508-Q511 PolarHBondContact O-N 3.16Å
512S96Very high95.5Very high81 Ų8154 Ų5457%0.56628%0.275SS*.Hα-helixtrans-83.1-31.4-179.2-58.20000114.2V508 R509 F510V508-S512 PolarHBondContact O-N 3.41Å; V508-S512 PolarHBondContact O-OG 3.26Å; V508-S512 VanDerWaalsContact O-OG 3.14Å; R509-S512 PolarHBondContact O-N 3.33Å; F510-S512 VanDerWaalsContact C-N 3.29Å; F510-S512 PolarHBondContact O-N 3.26Å
513H95.8Very high95.4Very high113 Ų11359 Ų5952%0.52330%0.3SS..Hα-helixtrans-140.813.7-166.7-5794.5000113.9R509 G517R509-H513 PolarHBondContact O-N 3.49Å; H513-G517 PolarHBondContact O-N 3.13Å
514G94.7Very high95.4Very high30 Ų3060.2 Ų60.231%0.30931%0.308SS..Hα-helixtrans61.3-156.5179.900000114.3F510 E516 G517 L518F510-G514 WeakPolarHBondContact O-CA 3.49Å; F510-G514 PolarHBondContact O-N 2.7Å; G514-E516 VanDerWaalsContact C-N 3.31Å; G514-E516 PolarHBondContact O-N 3.23Å; G514-G517 PolarHBondContact O-N 2.69Å; G514-L518 PolarHBondContact O-N 2.68Å
515L95.3Very high95.4Very high33 Ų3356.1 Ų56.117%0.17328%0.279CS..Hα-helixtrans-65.3-32.7-179.1-64.9173000112.8L248 P249 L253 F510 L518 N519 I566 W567L248-L515 HydrophobicContact CD2-CB 3.9Å; P249-L515 HydrophobicContact CG-CD1 3.9Å; L253-L515 HydrophobicContact CD1-CD1 3.88Å; F510-L515 HydrophobicContact CD2-CD2 4.05Å; F510-L515 HydrophobicContact CE2-CD2 3.66Å; F510-L515 HydrophobicContact CE2-CG 4.07Å; L515-L518 PolarHBondContact O-N 2.59Å; L515-N519 WeakPolarHBondContact O-CB 3.41Å; L515-N519 PolarHBondContact O-N 2.67Å; L515-I566 HydrophobicContact CB-CG2 4.42Å; L515-I566 HydrophobicContact CD2-CG2 3.94Å; L515-W567 HydrophobicContact CD1-CE3 4.01Å
516E95.3Very high95.4Very high99 Ų9954.1 Ų54.146%0.46327%0.274SS..Hα-helixtrans-63.7-46.9178-169.1-168.8158.600111.3L248 G514 L518 N519 K520L248-E516 HydrophobicContact CD1-CB 4.17Å; L248-E516 HydrophobicContact CD1-CG 4.41Å; L248-E516 HydrophobicContact CD2-CB 4.28Å; G514-E516 VanDerWaalsContact C-N 3.31Å; G514-E516 PolarHBondContact O-N 3.23Å; E516-L518 VanDerWaalsContact C-N 3.31Å; E516-L518 PolarHBondContact O-N 2.97Å; E516-N519 PolarHBondContact O-N 3.13Å; E516-K520 WeakPolarHBondContact O-CG 3.22Å; E516-K520 PolarHBondContact O-N 2.87Å; E516-K520 VanDerWaalsContact OE1-CE 3.27Å; E516-K520 WeakPolarHBondContact OE1-CE 3.45Å; E516-K520 IonicContact OE1-NZ 3.04Å; E516-K520 PolarHBondContact OE1-NZ 2.99Å
517G95.9Very high95.1Very high12 Ų1257.2 Ų57.212%0.12431%0.306CS..Hα-helixtrans-65.4-34.617600000113.1H513 G514 E521H513-G517 PolarHBondContact O-N 3.13Å; G514-G517 PolarHBondContact O-N 2.69Å; G517-E521 WeakPolarHBondContact O-CB 3.36Å; G517-E521 PolarHBondContact O-N 3.2Å
518L96.9Very high94.9Very high1 Ų158.6 Ų58.61%0.00531%0.311CS..Hα-helixtrans-63.4-48.3172.9178.959.5000111.3A501 H506 F510 G514 L515 E516 K520 E521 I522 I566 L572A501-L518 HydrophobicContact CB-CD1 4.08Å; A501-L518 HydrophobicContact CB-CD2 4.48Å; H506-L518 HydrophobicContact CB-CD1 3.65Å; F510-L518 HydrophobicContact CB-CB 4.4Å; F510-L518 HydrophobicContact CD2-CD2 4.41Å; G514-L518 PolarHBondContact O-N 2.68Å; L515-L518 PolarHBondContact O-N 2.59Å; E516-L518 VanDerWaalsContact C-N 3.31Å; E516-L518 PolarHBondContact O-N 2.97Å; L518-K520 VanDerWaalsContact C-N 3.34Å; L518-K520 PolarHBondContact O-N 2.67Å; L518-E521 PolarHBondContact O-N 3.27Å; L518-E521 VanDerWaalsContact O-N 3.16Å; L518-I522 HydrophobicContact CD1-CD1 4.45Å; L518-I522 HydrophobicContact CD1-CG1 4.13Å; L518-I522 HydrophobicContact CG-CG1 4.41Å; L518-I522 VanDerWaalsContact O-CG1 3.31Å; L518-I522 WeakPolarHBondContact O-CG1 3.41Å; L518-I522 PolarHBondContact O-N 3.15Å; L518-I566 HydrophobicContact CD2-CD1 4.29Å; L518-I566 HydrophobicContact CD2-CG1 3.51Å; L518-I566 HydrophobicContact CG-CD1 4.45Å; L518-I566 HydrophobicContact CG-CG1 3.87Å; L518-L572 HydrophobicContact CD1-CD1 4.03Å; L518-L572 HydrophobicContact CD2-CD1 3.77Å; L518-L572 HydrophobicContact CD2-CG 4.48Å
519N95.9Very high94.8Very high4 Ų454.8 Ų54.82%0.02129%0.288CS..Hα-helixtrans-56.1-46.7176.9-86.2-12000111.9M246 L515 E516 E521 I522 M523 I566M246-N519 HydrophobicContact CE-CB 3.66Å; M246-N519 PolarHBondContact O-ND2 2.78Å; M246-N519 HydrophobicContact SD-CB 3.8Å; L515-N519 WeakPolarHBondContact O-CB 3.41Å; L515-N519 PolarHBondContact O-N 2.67Å; E516-N519 PolarHBondContact O-N 3.13Å; N519-E521 VanDerWaalsContact C-N 3.34Å; N519-E521 PolarHBondContact O-N 2.81Å; N519-I522 PolarHBondContact O-N 3.4Å; N519-M523 WeakPolarHBondContact O-CB 3.49Å; N519-M523 PolarHBondContact O-N 3.02Å; N519-I566 WeakPolarHBondContact OD1-CB 3.36Å; N519-I566 VanDerWaalsContact OD1-CG2 3.22Å; N519-I566 WeakPolarHBondContact OD1-CG2 3.41Å
520K96Very high94.7Very high119 Ų11950.4 Ų50.452%0.51727%0.274SS..Hα-helixtrans-61.1-40.8176.6-71.7176.8-174.91690112.4E516 L518 M524E516-K520 WeakPolarHBondContact O-CG 3.22Å; E516-K520 PolarHBondContact O-N 2.87Å; E516-K520 VanDerWaalsContact OE1-CE 3.27Å; E516-K520 WeakPolarHBondContact OE1-CE 3.45Å; E516-K520 IonicContact OE1-NZ 3.04Å; E516-K520 PolarHBondContact OE1-NZ 2.99Å; L518-K520 VanDerWaalsContact C-N 3.34Å; L518-K520 PolarHBondContact O-N 2.67Å; K520-M524 WeakPolarHBondContact O-CB 3.46Å; K520-M524 PolarHBondContact O-N 2.54Å
521E96.8Very high94.2Very high18 Ų1851.3 Ų51.38%0.08429%0.285CS..Hα-helixtrans-66.7-43.5177.6-171.176.2-167.200111.5R505 R509 G517 L518 N519 M524 E525R505-E521 WeakPolarHBondContact CD-OE1 3.44Å; R505-E521 IonicContact NE-OE1 2.65Å; R509-E521 HydrophobicContact CB-CB 4.39Å; R509-E521 HydrophobicContact CG-CB 4.05Å; R509-E521 HydrophobicContact CG-CG 3.89Å; R509-E521 WeakPolarHBondContact CG-OE2 3.22Å; R509-E521 IonicContact CZ-OE2 3.63Å; R509-E521 IonicContact NE-OE2 3.63Å; R509-E521 PolarHBondContact NE-OE2 2.81Å; R509-E521 IonicContact NH2-OE2 3.86Å; G517-E521 WeakPolarHBondContact O-CB 3.36Å; G517-E521 PolarHBondContact O-N 3.2Å; L518-E521 PolarHBondContact O-N 3.27Å; L518-E521 VanDerWaalsContact O-N 3.16Å; N519-E521 VanDerWaalsContact C-N 3.34Å; N519-E521 PolarHBondContact O-N 2.81Å; E521-M524 HydrophobicContact CG-CE 4.34Å; E521-M524 PolarHBondContact O-N 3.41Å; E521-M524 VanDerWaalsContact OE1-CE 3.25Å; E521-M524 WeakPolarHBondContact OE1-CE 3.28Å; E521-E525 WeakPolarHBondContact O-CG 3.4Å; E521-E525 PolarHBondContact O-N 2.88Å
522I96.3Very high93.9Very high1 Ų149.7 Ų49.71%0.00527%0.273CS..Hα-helixtrans-61.8-47176.3-65-69.3000111L244 E498 A501 L518 N519 M524 E525 L526 I566L244-I522 HydrophobicContact CD1-CG2 4.47Å; L244-I522 HydrophobicContact CD2-CG2 3.93Å; E498-I522 WeakPolarHBondContact O-CD1 3.39Å; E498-I522 WeakPolarHBondContact O-CG2 3.47Å; A501-I522 HydrophobicContact CB-CD1 4.13Å; L518-I522 HydrophobicContact CD1-CD1 4.45Å; L518-I522 HydrophobicContact CD1-CG1 4.13Å; L518-I522 HydrophobicContact CG-CG1 4.41Å; L518-I522 VanDerWaalsContact O-CG1 3.31Å; L518-I522 WeakPolarHBondContact O-CG1 3.41Å; L518-I522 PolarHBondContact O-N 3.15Å; N519-I522 PolarHBondContact O-N 3.4Å; I522-M524 VanDerWaalsContact C-N 3.28Å; I522-M524 PolarHBondContact O-N 3.11Å; I522-E525 PolarHBondContact O-N 3.31Å; I522-E525 VanDerWaalsContact O-N 3.17Å; I522-L526 HydrophobicContact CG2-CD1 4.1Å; I522-L526 HydrophobicContact CG2-CG 4.44Å; I522-L526 WeakPolarHBondContact O-CG 3.41Å; I522-L526 PolarHBondContact O-N 2.98Å; I522-I566 HydrophobicContact CG1-CD1 4.18Å
523M94.9Very high93.5Very high108 Ų10846.9 Ų46.953%0.53225%0.252SS..Hα-helixtrans-56.6-43.2176-177.8-179.9167.200111.7L244 M246 N519 G527L244-M523 HydrophobicContact CD2-CB 3.97Å; M246-M523 HydrophobicContact CE-CB 4.41Å; M246-M523 HydrophobicContact CE-SD 4.09Å; N519-M523 WeakPolarHBondContact O-CB 3.49Å; N519-M523 PolarHBondContact O-N 3.02Å; M523-G527 PolarHBondContact O-N 2.86Å
524M93.9Very high93.4Very high70 Ų7041.5 Ų41.535%0.34523%0.227SC..Hα-helixtrans-64.4-41.3177.1-179.9-82.6-5800112.3K520 E521 I522 G527 R528K520-M524 WeakPolarHBondContact O-CB 3.46Å; K520-M524 PolarHBondContact O-N 2.54Å; E521-M524 HydrophobicContact CG-CE 4.34Å; E521-M524 PolarHBondContact O-N 3.41Å; E521-M524 VanDerWaalsContact OE1-CE 3.25Å; E521-M524 WeakPolarHBondContact OE1-CE 3.28Å; I522-M524 VanDerWaalsContact C-N 3.28Å; I522-M524 PolarHBondContact O-N 3.11Å; M524-G527 PolarHBondContact O-N 3.01Å; M524-R528 WeakPolarHBondContact O-CG 3.46Å; M524-R528 PolarHBondContact O-N 2.99Å; M524-R528 VanDerWaalsContact SD-CD 3.51Å; M524-R528 HydrophobicContact SD-CG 4.42Å; M524-R528 PolarHBondContact SD-NE 3.39Å; M524-R528 VanDerWaalsContact SD-NE 3.41Å
525E92.9Very high93.4Very high2 Ų240.1 Ų40.11%0.00921%0.213CC..Hα-helixtrans-63-48175.8-70.6-53.5145.300112.5E498 R505 E521 I522 G527 R528 I529E498-E525 HydrophobicContact CB-CB 4.25Å; E498-E525 HydrophobicContact CG-CB 4.18Å; R505-E525 IonicContact CZ-OE1 3.31Å; R505-E525 IonicContact CZ-OE2 3.78Å; R505-E525 IonicContact NE-OE1 3.96Å; R505-E525 PolarHBondContact NE-OE1 3.23Å; R505-E525 IonicContact NH1-OE1 2.72Å; R505-E525 PolarHBondContact NH1-OE1 3.38Å; R505-E525 IonicContact NH1-OE2 2.61Å; R505-E525 IonicContact NH2-OE1 3.48Å; R505-E525 PolarHBondContact NH2-OE1 3.38Å; R505-E525 IonicContact NH2-OE2 3.54Å; R505-E525 PolarHBondContact NH2-OE2 3.09Å; E521-E525 WeakPolarHBondContact O-CG 3.4Å; E521-E525 PolarHBondContact O-N 2.88Å; I522-E525 PolarHBondContact O-N 3.31Å; I522-E525 VanDerWaalsContact O-N 3.17Å; E525-G527 VanDerWaalsContact C-N 3.27Å; E525-G527 PolarHBondContact O-N 2.94Å; E525-R528 WeakPolarHBondContact O-CG 3.12Å; E525-R528 PolarHBondContact O-N 3.44Å; E525-R528 VanDerWaalsContact O-N 3.15Å; E525-R528 IonicContact OE1-CZ 3.66Å; E525-R528 VanDerWaalsContact OE1-CZ 3.25Å; E525-R528 IonicContact OE1-NE 3.16Å; E525-R528 PolarHBondContact OE1-NE 2.71Å; E525-R528 IonicContact OE1-NH2 2.78Å; E525-R528 PolarHBondContact OE1-NH2 3.16Å; E525-R528 IonicContact OE2-CZ 3.53Å; E525-R528 IonicContact OE2-NE 3.16Å; E525-R528 PolarHBondContact OE2-NE 3.15Å; E525-R528 VanDerWaalsContact OE2-NE 3.16Å; E525-R528 IonicContact OE2-NH2 2.74Å; E525-R528 PolarHBondContact OE2-NH2 3.3Å; E525-I529 PolarHBondContact O-N 2.86Å
526L92.6Very high93.4Very high39 Ų3938.7 Ų38.720%0.20421%0.205CC..Hα-helixtrans-61.9-37.9178-63.6177.8000111.4L244 E498 Q499 I522 R528 I529L244-L526 HydrophobicContact CD2-CD1 4.44Å; E498-L526 HydrophobicContact CB-CD2 3.92Å; Q499-L526 HydrophobicContact CG-CD2 3.58Å; I522-L526 HydrophobicContact CG2-CD1 4.1Å; I522-L526 HydrophobicContact CG2-CG 4.44Å; I522-L526 WeakPolarHBondContact O-CG 3.41Å; I522-L526 PolarHBondContact O-N 2.98Å; L526-R528 VanDerWaalsContact C-N 3.26Å; L526-R528 PolarHBondContact O-N 3.16Å; L526-I529 WeakPolarHBondContact O-CG2 3.43Å
527G90.8Very high93.5Very high65 Ų6534.2 Ų34.267%0.6718%0.184SC*.Hα-helixtrans-66.6-21.8177.100000114.9M523 M524 E525M523-G527 PolarHBondContact O-N 2.86Å; M524-G527 PolarHBondContact O-N 3.01Å; E525-G527 VanDerWaalsContact C-N 3.27Å; E525-G527 PolarHBondContact O-N 2.94Å
528R91.1Very high93.5Very high65 Ų6533.6 Ų33.625%0.24518%0.178CC..Hα-helixtrans-1130.4-177.776-177.9-174.4174.4-0.8115R505 M524 E525 L526 S530 S531 R532R505-R528 VanDerWaalsContact NH1-NH2 3.13Å; M524-R528 WeakPolarHBondContact O-CG 3.46Å; M524-R528 PolarHBondContact O-N 2.99Å; M524-R528 VanDerWaalsContact SD-CD 3.51Å; M524-R528 HydrophobicContact SD-CG 4.42Å; M524-R528 PolarHBondContact SD-NE 3.39Å; M524-R528 VanDerWaalsContact SD-NE 3.41Å; E525-R528 WeakPolarHBondContact O-CG 3.12Å; E525-R528 PolarHBondContact O-N 3.44Å; E525-R528 VanDerWaalsContact O-N 3.15Å; E525-R528 IonicContact OE1-CZ 3.66Å; E525-R528 VanDerWaalsContact OE1-CZ 3.25Å; E525-R528 IonicContact OE1-NE 3.16Å; E525-R528 PolarHBondContact OE1-NE 2.71Å; E525-R528 IonicContact OE1-NH2 2.78Å; E525-R528 PolarHBondContact OE1-NH2 3.16Å; E525-R528 IonicContact OE2-CZ 3.53Å; E525-R528 IonicContact OE2-NE 3.16Å; E525-R528 PolarHBondContact OE2-NE 3.15Å; E525-R528 VanDerWaalsContact OE2-NE 3.16Å; E525-R528 IonicContact OE2-NH2 2.74Å; E525-R528 PolarHBondContact OE2-NH2 3.3Å; L526-R528 VanDerWaalsContact C-N 3.26Å; L526-R528 PolarHBondContact O-N 3.16Å; R528-S530 PolarHBondContact O-N 3.34Å; R528-S531 PolarHBondContact O-N 3.25Å; R528-S531 PolarHBondContact O-OG 2.56Å; R528-R532 HydrophobicContact CB-CG 4.11Å; R528-R532 HydrophobicContact CG-CB 4.49Å; R528-R532 HydrophobicContact CG-CG 3.77Å; R528-R532 WeakPolarHBondContact O-CB 3.44Å; R528-R532 WeakPolarHBondContact O-CG 3.45Å; R528-R532 PolarHBondContact O-N 3.34Å
529I93.1Very high93.6Very high3 Ų333.6 Ų33.62%0.01518%0.178CC..Hα-helixtrans-58.2-34.3-174.3-162.7173.7000112.4E498 E525 L526 S531 N533 L534 L553E498-I529 HydrophobicContact CG-CD1 4.06Å; E498-I529 HydrophobicContact CG-CG1 4.49Å; E525-I529 PolarHBondContact O-N 2.86Å; L526-I529 WeakPolarHBondContact O-CG2 3.43Å; I529-S531 PolarHBondContact O-N 3.1Å; I529-N533 HydrophobicContact CG1-CB 4.47Å; I529-N533 PolarHBondContact O-N 3.09Å; I529-N533 VanDerWaalsContact O-N 3.1Å; I529-L534 HydrophobicContact CD1-CD1 4.4Å; I529-L534 HydrophobicContact CG1-CD1 4.04Å; I529-L534 HydrophobicContact CG1-CG 4.21Å; I529-L534 HydrophobicContact CG2-CD1 4.04Å; I529-L534 PolarHBondContact O-N 2.82Å; I529-L553 HydrophobicContact CD1-CD1 3.95Å; I529-L553 HydrophobicContact CD1-CD2 3.9Å
530S92.8Very high93.7Very high19 Ų1933.4 Ų33.413%0.13318%0.177CC..Iπ-helixtrans-61.2-41.5179.263.40000113.1F138 R528 G535F138-S530 WeakPolarHBondContact O-CA 3.32Å; F138-S530 WeakPolarHBondContact O-CB 3.47Å; R528-S530 PolarHBondContact O-N 3.34Å; S530-G535 PolarHBondContact O-N 3.5Å
531S86.4Confident93.8Very high58 Ų5827.8 Ų27.841%0.40615%0.153SC..Iπ-helixtrans-93.6-24.5-176.761.60000113.3R528 I529R528-S531 PolarHBondContact O-N 3.25Å; R528-S531 PolarHBondContact O-OG 2.56Å; I529-S531 PolarHBondContact O-N 3.1Å
532R88.4Confident93.8Very high103 Ų10326.9 Ų26.939%0.38915%0.149SC..Iπ-helixtrans-90.6-33.2-177.7-69.8-55-160.6149.4-1.6115.1R528 R536R528-R532 HydrophobicContact CB-CG 4.11Å; R528-R532 HydrophobicContact CG-CB 4.49Å; R528-R532 HydrophobicContact CG-CG 3.77Å; R528-R532 WeakPolarHBondContact O-CB 3.44Å; R528-R532 WeakPolarHBondContact O-CG 3.45Å; R528-R532 PolarHBondContact O-N 3.34Å; R532-R536 PolarHBondContact O-NH1 2.98Å
533N88.3Confident93.9Very high22 Ų2227 Ų2712%0.11815%0.149CC..Iπ-helixtrans-124.2-60.2-172.4-65.592.4000111.4I529 G535 R536 D537I529-N533 HydrophobicContact CG1-CB 4.47Å; I529-N533 PolarHBondContact O-N 3.09Å; I529-N533 VanDerWaalsContact O-N 3.1Å; N533-G535 PolarHBondContact O-N 2.91Å; N533-R536 PolarHBondContact O-N 3.02Å; N533-D537 WeakPolarHBondContact O-CB 3.41Å; N533-D537 PolarHBondContact O-N 3.05Å
534L93.9Very high94.1Very high0 Ų024.1 Ų24.10%013%0.134CC..Iπ-helixtrans-67.6-39.3-159.7-64.9169000113.9F138 G139 R140 I494 I529 D537 D538 F550 L553F138-L534 HydrophobicContact CB-CD1 4.19Å; F138-L534 WeakPolarHBondContact O-CD1 3.2Å; G139-L534 VanDerWaalsContact O-CB 3.25Å; G139-L534 WeakPolarHBondContact O-CB 3.38Å; R140-L534 HydrophobicContact CG-CD1 4.02Å; R140-L534 HydrophobicContact CG-CD2 4.41Å; I494-L534 HydrophobicContact CG2-CD2 3.89Å; I529-L534 HydrophobicContact CD1-CD1 4.4Å; I529-L534 HydrophobicContact CG1-CD1 4.04Å; I529-L534 HydrophobicContact CG1-CG 4.21Å; I529-L534 HydrophobicContact CG2-CD1 4.04Å; I529-L534 PolarHBondContact O-N 2.82Å; L534-D537 PolarHBondContact O-N 3.48Å; L534-D538 VanDerWaalsContact O-CB 3.24Å; L534-D538 WeakPolarHBondContact O-CB 3.39Å; L534-D538 PolarHBondContact O-N 3.27Å; L534-F550 HydrophobicContact CD2-CD1 3.85Å; L534-F550 HydrophobicContact CD2-CE1 3.53Å; L534-F550 HydrophobicContact CD2-CE2 4.44Å; L534-F550 HydrophobicContact CD2-CG 4.44Å; L534-F550 HydrophobicContact CD2-CZ 3.85Å; L534-L553 HydrophobicContact CD1-CD1 3.8Å; L534-L553 HydrophobicContact CD2-CD1 3.71Å; L534-L553 HydrophobicContact CG-CD1 4.34Å
535G94.3Very high94.2Very high1 Ų121.1 Ų21.11%0.0112%0.122CC..Hα-helixtrans-61.3-48.3176.600000113.3S530 N533 R539S530-G535 PolarHBondContact O-N 3.5Å; N533-G535 PolarHBondContact O-N 2.91Å; G535-R539 WeakPolarHBondContact O-CG 3.33Å; G535-R539 PolarHBondContact O-N 3.36Å
536R95.4Very high94.4Very high4 Ų421.4 Ų21.42%0.01512%0.123CC..Hα-helixtrans-61.2-50.5176.4177.7-16565.5-131.6-11.2110.9I449 L452 D457 I460 R532 N533 D538 R539 V540I449-R536 HydrophobicContact CG1-CG 4.37Å; I449-R536 HydrophobicContact CG2-CG 4.42Å; L452-R536 HydrophobicContact CD1-CB 3.9Å; D457-R536 IonicContact OD1-NH1 3.39Å; D457-R536 PolarHBondContact OD1-NH1 3.03Å; I460-R536 VanDerWaalsContact CG2-NH2 3.3Å; R532-R536 PolarHBondContact O-NH1 2.98Å; N533-R536 PolarHBondContact O-N 3.02Å; R536-D538 VanDerWaalsContact C-N 3.34Å; R536-D538 PolarHBondContact O-N 3.16Å; R536-R539 PolarHBondContact O-N 2.94Å; R536-V540 WeakPolarHBondContact O-CG2 3.47Å; R536-V540 PolarHBondContact O-N 3.45Å
537D96.1Very high94.7Very high4 Ų419.6 Ų19.62%0.02111%0.113CC..Hα-helixtrans-66.5-37.8-172.6-63.6-11.2000110.9I494 N533 L534 V540 I541I494-D537 HydrophobicContact CD1-CB 4.19Å; I494-D537 WeakPolarHBondContact CD1-OD2 2.93Å; N533-D537 WeakPolarHBondContact O-CB 3.41Å; N533-D537 PolarHBondContact O-N 3.05Å; L534-D537 PolarHBondContact O-N 3.48Å; D537-V540 WeakPolarHBondContact O-CG2 3.41Å; D537-I541 WeakPolarHBondContact O-CB 3.43Å; D537-I541 WeakPolarHBondContact O-CD1 3.48Å; D537-I541 WeakPolarHBondContact O-CG1 3.38Å; D537-I541 PolarHBondContact O-N 3.4Å
538D97.7Very high95Very high0 Ų016.5 Ų16.50%08%0.081CC..Hα-helixtrans-64.5-37.4173.3-176.270.9000112.8M1 R30 R141 S142 L534 R536 G542M1-D538 WeakPolarHBondContact CE-OD1 3.5Å; R30-D538 IonicContact CZ-OD2 3.13Å; R30-D538 PolarHBondContact NH1-O 2.72Å; R30-D538 IonicContact NH1-OD2 2.67Å; R30-D538 IonicContact NH2-OD1 2.98Å; R30-D538 IonicContact NH2-OD2 2.81Å; R30-D538 PolarHBondContact NH2-OD2 3.32Å; R141-D538 WeakPolarHBondContact CD-OD1 3.3Å; R141-D538 IonicContact CZ-OD1 3.96Å; R141-D538 IonicContact NH1-OD1 3.7Å; R141-D538 PolarHBondContact NH1-OD1 2.72Å; S142-D538 PolarHBondContact N-OD2 2.76Å; L534-D538 VanDerWaalsContact O-CB 3.24Å; L534-D538 WeakPolarHBondContact O-CB 3.39Å; L534-D538 PolarHBondContact O-N 3.27Å; R536-D538 VanDerWaalsContact C-N 3.34Å; R536-D538 PolarHBondContact O-N 3.16Å; D538-G542 PolarHBondContact O-N 3.02Å
539R97.4Very high95.3Very high1 Ų113.5 Ų13.50%0.0047%0.07CC..Hα-helixtrans-68.3-48.3176.4-73.9-173.9-61.7-106.21.6112.6S142 L144 V159 E172 L448 I449 Q450 G535 R536 G542 D543S142-R539 PolarHBondContact OG-NH1 2.67Å; L144-R539 VanDerWaalsContact CD2-NH1 3.29Å; V159-R539 HydrophobicContact CB-CG 4.47Å; V159-R539 HydrophobicContact CG2-CG 4.42Å; E172-R539 IonicContact OE1-NH1 3.76Å; E172-R539 IonicContact OE2-CZ 2.61Å; E172-R539 IonicContact OE2-NH1 3.29Å; E172-R539 PolarHBondContact OE2-NH1 3.39Å; E172-R539 IonicContact OE2-NH2 3.64Å; L448-R539 HydrophobicContact CB-CB 4.46Å; L448-R539 VanDerWaalsContact O-CB 3.32Å; L448-R539 WeakPolarHBondContact O-CB 3.39Å; L448-R539 WeakPolarHBondContact O-CD 3.42Å; L448-R539 PolarHBondContact O-NE 2.95Å; I449-R539 PolarHBondContact O-NH2 3.24Å; Q450-R539 PolarHBondContact O-NE 2.8Å; Q450-R539 VanDerWaalsContact O-NE 3.09Å; Q450-R539 PolarHBondContact O-NH1 3.29Å; Q450-R539 PolarHBondContact O-NH2 3.03Å; G535-R539 WeakPolarHBondContact O-CG 3.33Å; G535-R539 PolarHBondContact O-N 3.36Å; R536-R539 PolarHBondContact O-N 2.94Å; R539-G542 PolarHBondContact O-N 3.48Å; R539-D543 PolarHBondContact O-N 3.29Å; R539-D543 VanDerWaalsContact O-N 3.15Å
540V97.8Very high95.5Very high0 Ų013.5 Ų13.50%07%0.07CC..Hα-helixtrans-71-35.4-176.7-61.90000112.9I445 L448 I449 V464 W465 R536 D537I445-V540 HydrophobicContact CG2-CG1 4.47Å; L448-V540 HydrophobicContact CB-CG1 3.87Å; I449-V540 HydrophobicContact CG1-CG1 4.35Å; V464-V540 HydrophobicContact CB-CG2 3.97Å; V464-V540 HydrophobicContact CG1-CG2 3.65Å; W465-V540 HydrophobicContact CB-CB 3.97Å; W465-V540 HydrophobicContact CB-CG1 4.46Å; W465-V540 HydrophobicContact CG-CB 4.39Å; R536-V540 WeakPolarHBondContact O-CG2 3.47Å; R536-V540 PolarHBondContact O-N 3.45Å; D537-V540 WeakPolarHBondContact O-CG2 3.41Å
541I98.4Very high95.8Very high0 Ų012.6 Ų12.60%06%0.064CC..Hα-helixtrans-71.7-42.7174.8-64.8170000110.1L325 V464 V490 T492 D537 D543 H544 K546 A548L325-I541 HydrophobicContact CD1-CD1 4.27Å; V464-I541 HydrophobicContact CG1-CD1 3.74Å; V464-I541 HydrophobicContact CG1-CG1 3.53Å; V490-I541 HydrophobicContact CB-CG2 4.46Å; V490-I541 HydrophobicContact CG2-CG2 4.4Å; T492-I541 HydrophobicContact CG2-CD1 4.22Å; D537-I541 WeakPolarHBondContact O-CB 3.43Å; D537-I541 WeakPolarHBondContact O-CD1 3.48Å; D537-I541 WeakPolarHBondContact O-CG1 3.38Å; D537-I541 PolarHBondContact O-N 3.4Å; I541-D543 PolarHBondContact O-N 3.45Å; I541-H544 PolarHBondContact O-N 2.91Å; I541-K546 CarbonylContact C-O 3.46Å; I541-K546 HydrophobicContact CG2-CB 4.05Å; I541-A548 HydrophobicContact CB-CB 4.43Å; I541-A548 HydrophobicContact CD1-CB 3.61Å; I541-A548 HydrophobicContact CG2-CB 4.19Å
542G97.9Very high96.4Very high0 Ų09.9 Ų9.90%04%0.044CC..Hα-helixtrans-60.8-27.9179.400000113.8M1 Q29 R30 D538 R539 H544 G545 K546M1-G542 VanDerWaalsContact SD-CA 3.54Å; Q29-G542 CarbonylContact C-O 3.53Å; R30-G542 VanDerWaalsContact CA-O 3.24Å; R30-G542 WeakPolarHBondContact CA-O 3.36Å; D538-G542 PolarHBondContact O-N 3.02Å; R539-G542 PolarHBondContact O-N 3.48Å; G542-H544 PolarHBondContact O-N 3.48Å; G542-G545 PolarHBondContact O-N 3.08Å; G542-K546 WeakPolarHBondContact CA-O 3.49Å
543D98Very high96.9Very high4 Ų45 Ų52%0.0213%0.026CC..THydrogen-bonded Turntrans-58.7-20178.2-16647.8000114.8Q29 R444 L448 W465 R539 I541Q29-D543 WeakPolarHBondContact CB-OD1 2.67Å; Q29-D543 PolarHBondContact NE2-O 3.26Å; Q29-D543 VanDerWaalsContact NE2-O 3.15Å; R444-D543 IonicContact CZ-OD1 3.45Å; R444-D543 IonicContact CZ-OD2 3.91Å; R444-D543 IonicContact NE-OD1 2.98Å; R444-D543 PolarHBondContact NE-OD1 2.87Å; R444-D543 IonicContact NE-OD2 3.99Å; R444-D543 PolarHBondContact NE-OD2 2.99Å; R444-D543 IonicContact NH2-OD1 3.05Å; R444-D543 PolarHBondContact NH2-OD1 3.28Å; L448-D543 HydrophobicContact CD1-CB 3.56Å; L448-D543 VanDerWaalsContact CD1-CG 3.46Å; L448-D543 WeakPolarHBondContact CD1-OD2 3.43Å; L448-D543 HydrophobicContact CD2-CB 4.3Å; W465-D543 PolarHBondContact NE1-OD2 3.37Å; R539-D543 PolarHBondContact O-N 3.29Å; R539-D543 VanDerWaalsContact O-N 3.15Å; I541-D543 PolarHBondContact O-N 3.45Å
544H98Very high97.4Very high46 Ų464.1 Ų4.121%0.2132%0.021CC..THydrogen-bonded Turntrans-97.611.9177.5-63.4-57.8000113.4W465 S468 R469 I541 G542 K546W465-H544 AromaticContact CD1-NE2 3.69Å; W465-H544 AromaticContact CD2-CE1 3.9Å; W465-H544 AromaticContact CD2-NE2 3.39Å; W465-H544 AromaticContact CE2-CE1 3.38Å; W465-H544 AromaticContact CE2-NE2 3.24Å; W465-H544 AromaticContact CE3-NE2 3.92Å; W465-H544 AromaticContact CG-NE2 3.71Å; W465-H544 AromaticContact CH2-CE1 3.73Å; W465-H544 AromaticContact CZ2-CE1 3.31Å; W465-H544 WeakPolarHBondContact CZ2-CE1 2.92Å; W465-H544 AromaticContact CZ2-NE2 3.69Å; W465-H544 AromaticContact NE1-CE1 3.78Å; W465-H544 AromaticContact NE1-NE2 3.43Å; W465-H544 PolarHBondContact NE1-NE2 3.17Å; W465-H544 PolarHBondContact O-NE2 3.49Å; W465-H544 VanDerWaalsContact O-NE2 3.11Å; S468-H544 PolarHBondContact OG-CD2 3.48Å; R469-H544 PolarHBondContact N-CD2 2.91Å; I541-H544 PolarHBondContact O-N 2.91Å; G542-H544 PolarHBondContact O-N 3.48Å; H544-K546 VanDerWaalsContact C-N 3.26Å; H544-K546 HydrophobicContact CB-CD 4.47Å; H544-K546 HydrophobicContact CB-CG 4.22Å; H544-K546 PolarHBondContact O-N 3.28Å
545G97.4Very high97.6Very high8 Ų84.2 Ų4.28%0.0822%0.022CC..THydrogen-bonded Turntrans62.536.6-173.500000111.7Q29 L54 G542Q29-G545 WeakPolarHBondContact O-CA 3.48Å; Q29-G545 PolarHBondContact O-N 3.3Å; Q29-G545 VanDerWaalsContact O-N 3.13Å; L54-G545 WeakPolarHBondContact CD1-O 3.45Å; L54-G545 VanDerWaalsContact CD2-O 3.31Å; L54-G545 WeakPolarHBondContact CD2-O 2.98Å; G542-G545 PolarHBondContact O-N 3.08Å
546K97.6Very high97.8Very high8 Ų87 Ų74%0.0354%0.037CC..  trans-124.9145.1-179.9-60.9-169-177.6-168.20111M1 S468 S485 A487 K488 V490 I541 G542 H544M1-K546 WeakPolarHBondContact CE-O 3.35Å; S468-K546 VanDerWaalsContact O-CD 3.25Å; S468-K546 WeakPolarHBondContact O-CD 3.48Å; S468-K546 VanDerWaalsContact O-CE 3.31Å; S468-K546 WeakPolarHBondContact O-CE 3.34Å; S468-K546 PolarHBondContact O-NZ 3.47Å; S468-K546 VanDerWaalsContact O-NZ 3.09Å; S485-K546 PolarHBondContact O-NZ 3.11Å; S485-K546 VanDerWaalsContact O-NZ 3.17Å; A487-K546 VanDerWaalsContact O-CD 3.23Å; A487-K546 WeakPolarHBondContact O-CD 3.04Å; A487-K546 WeakPolarHBondContact O-CE 3.33Å; K488-K546 CarbonylContact O-C 3.53Å; K488-K546 VanDerWaalsContact O-CA 3.29Å; K488-K546 WeakPolarHBondContact O-CA 3.42Å; V490-K546 HydrophobicContact CG2-CB 4.03Å; V490-K546 HydrophobicContact CG2-CD 3.79Å; I541-K546 CarbonylContact C-O 3.46Å; I541-K546 HydrophobicContact CG2-CB 4.05Å; G542-K546 WeakPolarHBondContact CA-O 3.49Å; H544-K546 VanDerWaalsContact C-N 3.26Å; H544-K546 HydrophobicContact CB-CD 4.47Å; H544-K546 HydrophobicContact CB-CG 4.22Å; H544-K546 PolarHBondContact O-N 3.28Å
547E97.5Very high97.9Very high0 Ų06.9 Ų6.90%04%0.036CC..EExtended strand (participates in β ladder)trans-100.5122.8177.4178.2172.986.500112M1 L54 L56 E78 R141 K488 V490 R549M1-E547 WeakPolarHBondContact CA-OE2 3.39Å; M1-E547 HydrophobicContact CB-CB 3.85Å; M1-E547 HydrophobicContact CB-CG 3.91Å; M1-E547 WeakPolarHBondContact CB-OE2 3.17Å; M1-E547 PolarHBondContact N-OE2 3.13Å; L54-E547 HydrophobicContact CD2-CB 4.29Å; L56-E547 HydrophobicContact CD1-CB 3.59Å; L56-E547 HydrophobicContact CD1-CG 4.02Å; L56-E547 WeakPolarHBondContact CD1-OE1 3.49Å; L56-E547 WeakPolarHBondContact CD1-OE2 3.13Å; E78-E547 WeakPolarHBondContact CG-OE1 3.46Å; E78-E547 WeakPolarHBondContact CG-OE2 3.46Å; R141-E547 IonicContact CZ-OE2 2.79Å; R141-E547 IonicContact NE-OE2 3.9Å; R141-E547 IonicContact NH2-OE1 2.74Å; R141-E547 IonicContact NH2-OE2 2.67Å; R141-E547 PolarHBondContact NH2-OE2 3.03Å; K488-E547 PolarHBondContact O-N 2.92Å; V490-E547 PolarHBondContact N-O 3.4Å; E547-R549 HydrophobicContact CG-CG 4.29Å; E547-R549 IonicContact OE1-CZ 3.38Å; E547-R549 VanDerWaalsContact OE1-CZ 3.29Å; E547-R549 IonicContact OE1-NE 3.66Å; E547-R549 PolarHBondContact OE1-NE 3.23Å; E547-R549 IonicContact OE1-NH2 3.31Å; E547-R549 PolarHBondContact OE1-NH2 3.35Å
548A97.3Very high98.1Very high0 Ų06.8 Ų6.80%04%0.036CC..EExtended strand (participates in β ladder)trans-71.5133.4165.700000111R141 V490 T492 I541 F550R141-A548 PolarHBondContact NH1-O 3.18Å; R141-A548 PolarHBondContact NH2-O 2.91Å; V490-A548 CarbonylContact O-C 3.56Å; V490-A548 WeakPolarHBondContact O-CA 3.3Å; T492-A548 HydrophobicContact CG2-CB 4.37Å; I541-A548 HydrophobicContact CB-CB 4.43Å; I541-A548 HydrophobicContact CD1-CB 3.61Å; I541-A548 HydrophobicContact CG2-CB 4.19Å; A548-F550 HydrophobicContact CB-CE1 4.2Å; A548-F550 HydrophobicContact CB-CE2 3.98Å; A548-F550 HydrophobicContact CB-CZ 3.56Å
549R97.9Very high98.1Very high3 Ų38 Ų81%0.0114%0.044CC..EExtended strand (participates in β ladder)trans-123.9141.9170-62.2-172.5179.3-168.4-11.5110.4E78 F80 R297 V489 V490 L491 T492 E547 P551E78-R549 IonicContact OE2-NH2 3.44Å; F80-R549 HydrophobicContact CZ-CG 4.49Å; R297-R549 VanDerWaalsContact C-NH1 3.32Å; R297-R549 HydrophobicContact CB-CB 4.25Å; R297-R549 HydrophobicContact CG-CB 4.1Å; R297-R549 VanDerWaalsContact O-CD 3.25Å; R297-R549 WeakPolarHBondContact O-CD 3.26Å; R297-R549 PolarHBondContact O-NH1 3.07Å; V489-R549 HydrophobicContact CG1-CG 3.98Å; V490-R549 PolarHBondContact O-N 3.08Å; L491-R549 HydrophobicContact CD2-CB 3.85Å; T492-R549 PolarHBondContact N-O 3.13Å; E547-R549 HydrophobicContact CG-CG 4.29Å; E547-R549 IonicContact OE1-CZ 3.38Å; E547-R549 VanDerWaalsContact OE1-CZ 3.29Å; E547-R549 IonicContact OE1-NE 3.66Å; E547-R549 PolarHBondContact OE1-NE 3.23Å; E547-R549 IonicContact OE1-NH2 3.31Å; E547-R549 PolarHBondContact OE1-NH2 3.35Å; R549-P551 WeakPolarHBondContact O-CD 3.47Å
550F97.9Very high98.2Very high3 Ų39.3 Ų9.31%0.0135%0.05CC..  trans-12385.5-166.3-50.6-86.2000110.9R140 R297 T492 I494 L534 A548 F552 L553 D554R140-F550 HydrophobicContact CB-CD2 4.01Å; R140-F550 HydrophobicContact CB-CE2 3.9Å; R140-F550 HydrophobicContact CG-CD2 3.81Å; R140-F550 HydrophobicContact CG-CE2 4.13Å; R140-F550 HydrophobicContact CG-CG 4.41Å; R297-F550 VanDerWaalsContact NE-C 3.27Å; R297-F550 PolarHBondContact NE-O 2.77Å; R297-F550 VanDerWaalsContact NE-O 3.09Å; R297-F550 PolarHBondContact NH2-O 2.89Å; T492-F550 WeakPolarHBondContact OG1-CD1 3.41Å; I494-F550 HydrophobicContact CB-CD1 4.11Å; I494-F550 HydrophobicContact CB-CE1 4.4Å; I494-F550 HydrophobicContact CD1-CE1 4.02Å; I494-F550 HydrophobicContact CG2-CD1 4.44Å; L534-F550 HydrophobicContact CD2-CD1 3.85Å; L534-F550 HydrophobicContact CD2-CE1 3.53Å; L534-F550 HydrophobicContact CD2-CE2 4.44Å; L534-F550 HydrophobicContact CD2-CG 4.44Å; L534-F550 HydrophobicContact CD2-CZ 3.85Å; A548-F550 HydrophobicContact CB-CE1 4.2Å; A548-F550 HydrophobicContact CB-CE2 3.98Å; A548-F550 HydrophobicContact CB-CZ 3.56Å; F550-F552 VanDerWaalsContact C-N 3.32Å; F550-F552 PolarHBondContact O-N 3.17Å; F550-L553 HydrophobicContact CB-CB 3.88Å; F550-L553 HydrophobicContact CB-CD1 4.14Å; F550-L553 HydrophobicContact CB-CG 4.27Å; F550-L553 HydrophobicContact CD1-CD1 4.45Å; F550-L553 HydrophobicContact CG-CD1 4.38Å; F550-L553 CarbonylContact O-C 3.57Å; F550-L553 PolarHBondContact O-N 3.36Å; F550-L553 VanDerWaalsContact O-N 3.15Å; F550-D554 PolarHBondContact O-N 3.34Å
551P98.6Very high98.2Very high0 Ų09.3 Ų9.30%05%0.05CC..G310 helixtrans-59.2-39.2-179.1-26.135.3000113.7L290 V294 I335 T492 R549 L553 D554L290-P551 HydrophobicContact CD1-CB 3.94Å; V294-P551 HydrophobicContact CG2-CB 3.73Å; V294-P551 HydrophobicContact CG2-CG 3.93Å; I335-P551 HydrophobicContact CD1-CG 4.14Å; I335-P551 HydrophobicContact CG1-CG 4.37Å; T492-P551 WeakPolarHBondContact O-CD 3.34Å; R549-P551 WeakPolarHBondContact O-CD 3.47Å; P551-L553 PolarHBondContact O-N 2.93Å; P551-D554 WeakPolarHBondContact O-CB 3.5Å; P551-D554 PolarHBondContact O-N 2.93Å
552F98.7Very high98.2Very high0 Ų09.7 Ų9.70%05%0.052CC..G310 helixtrans-70-16.4177.8-70.7-75.4000113.8F286 L290 D331 I335 A496 Q499 F550 V558 L584F286-F552 HydrophobicContact CZ-CE1 4.06Å; L290-F552 HydrophobicContact CD1-CD1 4.09Å; L290-F552 HydrophobicContact CD1-CE1 4.13Å; L290-F552 HydrophobicContact CD1-CG 4.46Å; L290-F552 HydrophobicContact CD2-CD1 4.46Å; L290-F552 HydrophobicContact CD2-CE1 3.72Å; L290-F552 HydrophobicContact CD2-CZ 3.95Å; D331-F552 HydrophobicContact CB-CE2 4.23Å; I335-F552 HydrophobicContact CD1-CD2 3.94Å; I335-F552 HydrophobicContact CD1-CE2 3.62Å; I335-F552 HydrophobicContact CG1-CD2 4.49Å; I335-F552 HydrophobicContact CG1-CE2 3.84Å; A496-F552 HydrophobicContact CB-CD1 3.96Å; A496-F552 HydrophobicContact CB-CD2 3.77Å; A496-F552 HydrophobicContact CB-CE1 4.01Å; A496-F552 HydrophobicContact CB-CE2 3.82Å; A496-F552 HydrophobicContact CB-CG 3.84Å; A496-F552 HydrophobicContact CB-CZ 3.94Å; Q499-F552 PolarHBondContact NE2-O 2.99Å; F550-F552 VanDerWaalsContact C-N 3.32Å; F550-F552 PolarHBondContact O-N 3.17Å; F552-V558 WeakPolarHBondContact O-CG2 3.21Å; F552-L584 HydrophobicContact CE1-CD1 4.06Å; F552-L584 HydrophobicContact CE1-CD2 4.36Å; F552-L584 HydrophobicContact CZ-CD1 3.94Å; F552-L584 HydrophobicContact CZ-CD2 4.07Å
553L98.4Very high98.2Very high2 Ų212.8 Ų12.81%0.017%0.073CC..G310 helixtrans-10728.2175-58.5176000111.3R140 I494 I529 L534 F550 P551 V558R140-L553 HydrophobicContact CG-CD1 4.37Å; R140-L553 PolarHBondContact NH1-O 3.34Å; I494-L553 HydrophobicContact CG2-CD1 4.49Å; I529-L553 HydrophobicContact CD1-CD1 3.95Å; I529-L553 HydrophobicContact CD1-CD2 3.9Å; L534-L553 HydrophobicContact CD1-CD1 3.8Å; L534-L553 HydrophobicContact CD2-CD1 3.71Å; L534-L553 HydrophobicContact CG-CD1 4.34Å; F550-L553 HydrophobicContact CB-CB 3.88Å; F550-L553 HydrophobicContact CB-CD1 4.14Å; F550-L553 HydrophobicContact CB-CG 4.27Å; F550-L553 HydrophobicContact CD1-CD1 4.45Å; F550-L553 HydrophobicContact CG-CD1 4.38Å; F550-L553 CarbonylContact O-C 3.57Å; F550-L553 PolarHBondContact O-N 3.36Å; F550-L553 VanDerWaalsContact O-N 3.15Å; P551-L553 PolarHBondContact O-N 2.93Å; L553-V558 HydrophobicContact CD2-CG2 4.4Å
554D98.6Very high98.2Very high2 Ų213.3 Ų13.31%0.0118%0.076CC..  trans-69.9137.3160.6-167.4-91.2000109.5A293 R297 F550 P551 N556 V557 V558A293-D554 HydrophobicContact CB-CB 3.54Å; R297-D554 IonicContact CZ-OD2 2.76Å; R297-D554 IonicContact NH1-OD2 3.09Å; R297-D554 PolarHBondContact NH1-OD2 3.44Å; R297-D554 VanDerWaalsContact NH2-CB 3.3Å; R297-D554 IonicContact NH2-OD2 3.34Å; R297-D554 PolarHBondContact NH2-OD2 3.28Å; F550-D554 PolarHBondContact O-N 3.34Å; P551-D554 WeakPolarHBondContact O-CB 3.5Å; P551-D554 PolarHBondContact O-N 2.93Å; D554-N556 PolarHBondContact O-N 3.34Å; D554-N556 WeakPolarHBondContact OD1-CB 3.34Å; D554-N556 PolarHBondContact OD1-N 3.27Å; D554-N556 PolarHBondContact OD1-ND2 3.08Å; D554-V557 HydrophobicContact CB-CB 4.01Å; D554-V557 HydrophobicContact CB-CG2 3.81Å; D554-V557 PolarHBondContact O-N 2.6Å; D554-V558 VanDerWaalsContact O-CG2 3.31Å; D554-V558 WeakPolarHBondContact O-CG2 3.33Å; D554-V558 PolarHBondContact O-N 3.06Å
555E98.3Very high98.1Very high2 Ų211.7 Ų11.71%0.0097%0.07CC..Hα-helixtrans-54.6-37.9-179.2-67.777.1-178.200111.3Q116 G117 F138 R140 P240 V241 S559Q116-E555 HydrophobicContact CB-CG 4.23Å; Q116-E555 HydrophobicContact CG-CB 4.39Å; Q116-E555 HydrophobicContact CG-CG 4.13Å; G117-E555 PolarHBondContact N-OE1 2.67Å; F138-E555 HydrophobicContact CE2-CG 4.29Å; R140-E555 IonicContact CZ-OE1 2.81Å; R140-E555 VanDerWaalsContact CZ-OE1 3.26Å; R140-E555 IonicContact NH1-OE1 2.69Å; R140-E555 PolarHBondContact NH1-OE1 3.17Å; R140-E555 IonicContact NH1-OE2 3.67Å; R140-E555 PolarHBondContact NH1-OE2 2.99Å; R140-E555 IonicContact NH2-OE1 3.78Å; R140-E555 PolarHBondContact NH2-OE1 2.78Å; P240-E555 HydrophobicContact CB-CG 3.93Å; P240-E555 HydrophobicContact CG-CG 4.1Å; V241-E555 HydrophobicContact CG1-CB 4.33Å; E555-S559 VanDerWaalsContact O-CB 3.26Å; E555-S559 WeakPolarHBondContact O-CB 3.42Å; E555-S559 PolarHBondContact O-N 2.74Å; E555-S559 PolarHBondContact O-OG 3.19Å
556N98.4Very high98.1Very high61 Ų6111.3 Ų11.333%0.3267%0.066SC..Hα-helixtrans-76.9-36.7179-55.3-71.4000112.1V289 D554 S559 F560V289-N556 HydrophobicContact CG2-CB 3.75Å; D554-N556 PolarHBondContact O-N 3.34Å; D554-N556 WeakPolarHBondContact OD1-CB 3.34Å; D554-N556 PolarHBondContact OD1-N 3.27Å; D554-N556 PolarHBondContact OD1-ND2 3.08Å; N556-S559 PolarHBondContact O-N 2.91Å; N556-F560 WeakPolarHBondContact O-CB 3.45Å; N556-F560 PolarHBondContact O-N 3.32Å
557V98.8Very high97.9Very high0 Ų013.8 Ų13.80%08%0.075CC..Hα-helixtrans-65-46.2175174.30000110.1F286 V289 L290 A293 D554 S559 F560 L561F286-V557 HydrophobicContact CE2-CG1 4.35Å; V289-V557 HydrophobicContact CG1-CG2 4.23Å; V289-V557 HydrophobicContact CG2-CG2 4.02Å; L290-V557 HydrophobicContact CB-CG2 4.47Å; L290-V557 HydrophobicContact CD1-CG1 4.4Å; L290-V557 HydrophobicContact CD1-CG2 4.18Å; A293-V557 HydrophobicContact CB-CG2 3.63Å; D554-V557 HydrophobicContact CB-CB 4.01Å; D554-V557 HydrophobicContact CB-CG2 3.81Å; D554-V557 PolarHBondContact O-N 2.6Å; V557-S559 VanDerWaalsContact C-N 3.33Å; V557-F560 PolarHBondContact O-N 3.37Å; V557-L561 HydrophobicContact CG1-CD1 4.06Å; V557-L561 HydrophobicContact CG1-CG 4.47Å; V557-L561 WeakPolarHBondContact O-CB 3.17Å; V557-L561 WeakPolarHBondContact O-CG 3.49Å; V557-L561 PolarHBondContact O-N 3.41Å
558V98.6Very high97.8Very high3 Ų316.4 Ų16.42%0.0189%0.087CC..Hα-helixtrans-64.8-40.3177.5176.40000110.3F138 V241 F552 L553 D554 L561 N562F138-V558 HydrophobicContact CE1-CB 4.44Å; F138-V558 HydrophobicContact CE1-CG1 3.99Å; F138-V558 HydrophobicContact CE1-CG2 4.03Å; F138-V558 HydrophobicContact CE2-CG2 4.35Å; F138-V558 HydrophobicContact CZ-CB 3.89Å; F138-V558 HydrophobicContact CZ-CG1 3.85Å; F138-V558 HydrophobicContact CZ-CG2 3.6Å; V241-V558 HydrophobicContact CB-CG1 4.25Å; V241-V558 HydrophobicContact CG1-CB 4.03Å; V241-V558 HydrophobicContact CG1-CG1 3.91Å; V241-V558 HydrophobicContact CG2-CG1 4.42Å; F552-V558 WeakPolarHBondContact O-CG2 3.21Å; L553-V558 HydrophobicContact CD2-CG2 4.4Å; D554-V558 VanDerWaalsContact O-CG2 3.31Å; D554-V558 WeakPolarHBondContact O-CG2 3.33Å; D554-V558 PolarHBondContact O-N 3.06Å; V558-L561 PolarHBondContact O-N 3.13Å; V558-N562 WeakPolarHBondContact O-CB 3.31Å; V558-N562 VanDerWaalsContact O-CG 3.22Å; V558-N562 PolarHBondContact O-N 2.91Å
559S98.4Very high97.8Very high24 Ų2416.5 Ų16.517%0.1689%0.088CC..Hα-helixtrans-63.9-45.2176.5-64.60000112.5V241 V242 E555 N556 V557 N562 S563V241-S559 VanDerWaalsContact CA-OG 3.27Å; V241-S559 WeakPolarHBondContact CA-OG 3.4Å; V242-S559 VanDerWaalsContact CG2-O 3.27Å; V242-S559 WeakPolarHBondContact CG2-O 3.24Å; V242-S559 PolarHBondContact N-OG 3.02Å; E555-S559 VanDerWaalsContact O-CB 3.26Å; E555-S559 WeakPolarHBondContact O-CB 3.42Å; E555-S559 PolarHBondContact O-N 2.74Å; E555-S559 PolarHBondContact O-OG 3.19Å; N556-S559 PolarHBondContact O-N 2.91Å; V557-S559 VanDerWaalsContact C-N 3.33Å; S559-N562 PolarHBondContact O-N 3.34Å; S559-S563 PolarHBondContact O-N 3.35Å
560F98.8Very high97.8Very high29 Ų2916.4 Ų16.413%0.1279%0.088CC..Hα-helixtrans-58.7-52.1174.6172.6-94.7000110.6V282 Q285 F286 V289 N556 V557 N562 S563 L564 L583V282-F560 HydrophobicContact CG1-CZ 4.1Å; V282-F560 WeakPolarHBondContact O-CZ 3.36Å; Q285-F560 HydrophobicContact CB-CD2 4.46Å; Q285-F560 HydrophobicContact CB-CE2 3.57Å; Q285-F560 HydrophobicContact CB-CZ 3.93Å; F286-F560 HydrophobicContact CB-CD1 4.37Å; F286-F560 HydrophobicContact CB-CE1 3.5Å; F286-F560 VanDerWaalsContact CB-CE1 3.5Å; F286-F560 HydrophobicContact CB-CZ 3.93Å; F286-F560 AromaticContact CD2-CD1 3.86Å; F286-F560 HydrophobicContact CD2-CD1 3.86Å; F286-F560 AromaticContact CD2-CE1 3.7Å; F286-F560 HydrophobicContact CD2-CE1 3.7Å; F286-F560 AromaticContact CG-CE1 3.99Å; F286-F560 HydrophobicContact CG-CE1 3.99Å; V289-F560 HydrophobicContact CG1-CB 4.09Å; V289-F560 HydrophobicContact CG1-CD1 4.05Å; V289-F560 HydrophobicContact CG1-CG 4.01Å; N556-F560 WeakPolarHBondContact O-CB 3.45Å; N556-F560 PolarHBondContact O-N 3.32Å; V557-F560 PolarHBondContact O-N 3.37Å; F560-N562 VanDerWaalsContact C-N 3.33Å; F560-N562 PolarHBondContact O-N 2.98Å; F560-S563 WeakPolarHBondContact O-CB 3.32Å; F560-S563 PolarHBondContact O-N 3.44Å; F560-S563 VanDerWaalsContact O-N 3.14Å; F560-S563 PolarHBondContact O-OG 3.31Å; F560-L564 HydrophobicContact CD1-CD1 4.39Å; F560-L564 HydrophobicContact CE1-CD1 3.66Å; F560-L564 HydrophobicContact CE1-CG 4.42Å; F560-L564 HydrophobicContact CZ-CD1 3.85Å; F560-L564 HydrophobicContact CZ-CD2 4.47Å; F560-L564 HydrophobicContact CZ-CG 4.41Å; F560-L564 PolarHBondContact O-N 2.78Å; F560-L583 HydrophobicContact CE1-CD2 4.36Å
561L98.7Very high97.6Very high1 Ų118.1 Ų18.11%0.00510%0.097CC..Hα-helixtrans-61.9-40178.3-70.5179.1000111.8F286 Q499 L500 V557 V558 S563 L564 K569 L583F286-L561 HydrophobicContact CD2-CD2 3.93Å; F286-L561 HydrophobicContact CD2-CG 4.48Å; F286-L561 HydrophobicContact CE2-CD1 4.08Å; F286-L561 HydrophobicContact CE2-CD2 3.72Å; F286-L561 HydrophobicContact CE2-CG 4.08Å; F286-L561 HydrophobicContact CZ-CD2 4.47Å; Q499-L561 HydrophobicContact CB-CD1 3.9Å; Q499-L561 HydrophobicContact CG-CD1 4.47Å; L500-L561 HydrophobicContact CD2-CD1 4.19Å; L500-L561 HydrophobicContact CD2-CD2 3.66Å; L500-L561 HydrophobicContact CG-CD1 4.42Å; V557-L561 HydrophobicContact CG1-CD1 4.06Å; V557-L561 HydrophobicContact CG1-CG 4.47Å; V557-L561 WeakPolarHBondContact O-CB 3.17Å; V557-L561 WeakPolarHBondContact O-CG 3.49Å; V557-L561 PolarHBondContact O-N 3.41Å; V558-L561 PolarHBondContact O-N 3.13Å; L561-S563 VanDerWaalsContact C-N 3.28Å; L561-S563 PolarHBondContact O-N 2.91Å; L561-L564 PolarHBondContact O-N 3.31Å; L561-K569 WeakPolarHBondContact O-CE 2.82Å; L561-K569 PolarHBondContact O-NZ 3.27Å; L561-L583 HydrophobicContact CD2-CD2 3.8Å
562N98Very high97.4Very high8 Ų818.3 Ų18.34%0.04310%0.098CC..Hα-helixtrans-64.9-32.5177.3-80.9-2.2000112.3V242 N245 V558 S559 F560 L564V242-N562 HydrophobicContact CG2-CB 3.8Å; V242-N562 WeakPolarHBondContact O-CB 3.09Å; V242-N562 PolarHBondContact O-ND2 3.11Å; N245-N562 WeakPolarHBondContact CB-O 3.38Å; N245-N562 PolarHBondContact N-O 3.3Å; V558-N562 WeakPolarHBondContact O-CB 3.31Å; V558-N562 VanDerWaalsContact O-CG 3.22Å; V558-N562 PolarHBondContact O-N 2.91Å; S559-N562 PolarHBondContact O-N 3.34Å; F560-N562 VanDerWaalsContact C-N 3.33Å; F560-N562 PolarHBondContact O-N 2.98Å; N562-L564 VanDerWaalsContact C-N 3.32Å; N562-L564 PolarHBondContact O-N 2.72Å
563S97.8Very high97Very high64 Ų6421.8 Ų21.845%0.44812%0.119SC..Hα-helixtrans-67-31.8177.977.30000113.3N245 S559 F560 L561N245-S563 PolarHBondContact ND2-O 2.98Å; S559-S563 PolarHBondContact O-N 3.35Å; F560-S563 WeakPolarHBondContact O-CB 3.32Å; F560-S563 PolarHBondContact O-N 3.44Å; F560-S563 VanDerWaalsContact O-N 3.14Å; F560-S563 PolarHBondContact O-OG 3.31Å; L561-S563 VanDerWaalsContact C-N 3.28Å; L561-S563 PolarHBondContact O-N 2.91Å
564L98.1Very high96.6Very high15 Ų1522 Ų228%0.07912%0.12CC..SBendtrans-75.1141.5-179.8-57.8178.4000111.2V282 F560 L561 N562 K569 L583V282-L564 HydrophobicContact CG1-CD1 3.67Å; V282-L564 HydrophobicContact CG1-CD2 4.03Å; F560-L564 HydrophobicContact CD1-CD1 4.39Å; F560-L564 HydrophobicContact CE1-CD1 3.66Å; F560-L564 HydrophobicContact CE1-CG 4.42Å; F560-L564 HydrophobicContact CZ-CD1 3.85Å; F560-L564 HydrophobicContact CZ-CD2 4.47Å; F560-L564 HydrophobicContact CZ-CG 4.41Å; F560-L564 PolarHBondContact O-N 2.78Å; L561-L564 PolarHBondContact O-N 3.31Å; N562-L564 VanDerWaalsContact C-N 3.32Å; N562-L564 PolarHBondContact O-N 2.72Å; L564-K569 HydrophobicContact CB-CG 4.37Å; L564-K569 WeakPolarHBondContact O-CE 3.32Å; L564-K569 PolarHBondContact O-NZ 2.95Å; L564-L583 HydrophobicContact CD1-CD2 3.75Å
565P96.6Very high96.2Very high13 Ų1323.3 Ų23.38%0.08413%0.129CC..  trans-67.8155.1167.930.8-34.9000111.1W567 E568P565-W567 VanDerWaalsContact C-N 3.26Å; P565-W567 HydrophobicContact CB-CD2 3.7Å; P565-W567 HydrophobicContact CB-CE3 3.79Å; P565-W567 HydrophobicContact CB-CH2 3.36Å; P565-W567 HydrophobicContact CB-CZ2 3.23Å; P565-W567 HydrophobicContact CB-CZ3 3.62Å; P565-W567 HydrophobicContact CG-CD2 4.06Å; P565-W567 VanDerWaalsContact CG-CE2 3.4Å; P565-W567 HydrophobicContact CG-CH2 4.14Å; P565-W567 HydrophobicContact CG-CZ2 3.47Å; P565-W567 VanDerWaalsContact CG-CZ2 3.47Å; P565-W567 PolarHBondContact O-N 3.16Å; P565-E568 HydrophobicContact CG-CB 4.42Å; P565-E568 HydrophobicContact CG-CG 3.96Å; P565-E568 WeakPolarHBondContact CG-OE1 3.25Å; P565-E568 PolarHBondContact O-N 3.42Å; P565-E568 VanDerWaalsContact O-N 3.13Å
566I96.1Very high95.8Very high0 Ų030.4 Ų30.40%016%0.156CC..Hα-helixtrans-62.6-28.6-171.6-169.659.2000114.2L515 L518 N519 I522 E568 K569 A570L515-I566 HydrophobicContact CB-CG2 4.42Å; L515-I566 HydrophobicContact CD2-CG2 3.94Å; L518-I566 HydrophobicContact CD2-CD1 4.29Å; L518-I566 HydrophobicContact CD2-CG1 3.51Å; L518-I566 HydrophobicContact CG-CD1 4.45Å; L518-I566 HydrophobicContact CG-CG1 3.87Å; N519-I566 WeakPolarHBondContact OD1-CB 3.36Å; N519-I566 VanDerWaalsContact OD1-CG2 3.22Å; N519-I566 WeakPolarHBondContact OD1-CG2 3.41Å; I522-I566 HydrophobicContact CG1-CD1 4.18Å; I566-E568 VanDerWaalsContact C-N 3.28Å; I566-E568 PolarHBondContact O-N 2.97Å; I566-K569 HydrophobicContact CD1-CB 4.37Å; I566-K569 HydrophobicContact CD1-CD 4.13Å; I566-K569 PolarHBondContact O-N 3.03Å; I566-K569 VanDerWaalsContact O-N 3.11Å; I566-A570 PolarHBondContact O-N 3.27Å
567W94.3Very high95.2Very high59 Ų5927.5 Ų27.522%0.22314%0.141CC..Hα-helixtrans-71.1-20.217957.383.6000113.6M247 P249 L253 L515 P565 A570M247-W567 HydrophobicContact CB-CH2 4.42Å; M247-W567 WeakPolarHBondContact O-CZ3 3.46Å; P249-W567 HydrophobicContact CB-CH2 4.27Å; P249-W567 HydrophobicContact CB-CZ2 4.43Å; P249-W567 HydrophobicContact CB-CZ3 4.41Å; P249-W567 VanDerWaalsContact CD-CZ3 3.47Å; P249-W567 HydrophobicContact CG-CZ3 4.37Å; L253-W567 HydrophobicContact CD1-CB 3.76Å; L253-W567 HydrophobicContact CD1-CD2 4.21Å; L253-W567 HydrophobicContact CD1-CG 3.87Å; L253-W567 HydrophobicContact CD2-CG 4.2Å; L515-W567 HydrophobicContact CD1-CE3 4.01Å; P565-W567 VanDerWaalsContact C-N 3.26Å; P565-W567 HydrophobicContact CB-CD2 3.7Å; P565-W567 HydrophobicContact CB-CE3 3.79Å; P565-W567 HydrophobicContact CB-CH2 3.36Å; P565-W567 HydrophobicContact CB-CZ2 3.23Å; P565-W567 HydrophobicContact CB-CZ3 3.62Å; P565-W567 HydrophobicContact CG-CD2 4.06Å; P565-W567 VanDerWaalsContact CG-CE2 3.4Å; P565-W567 HydrophobicContact CG-CH2 4.14Å; P565-W567 HydrophobicContact CG-CZ2 3.47Å; P565-W567 VanDerWaalsContact CG-CZ2 3.47Å; P565-W567 PolarHBondContact O-N 3.16Å; W567-A570 WeakPolarHBondContact CA-O 3.19Å
568E95.7Very high94.7Very high55 Ų5527.6 Ų27.626%0.25714%0.141SC..Hα-helixtrans-81-19.8171.3-70.4-176.9-141.100112H278 P565 I566H278-E568 IonicContact NE2-OE1 3.37Å; H278-E568 IonicContact NE2-OE2 3.25Å; H278-E568 PolarHBondContact NE2-OE2 3.22Å; P565-E568 HydrophobicContact CG-CB 4.42Å; P565-E568 HydrophobicContact CG-CG 3.96Å; P565-E568 WeakPolarHBondContact CG-OE1 3.25Å; P565-E568 PolarHBondContact O-N 3.42Å; P565-E568 VanDerWaalsContact O-N 3.13Å; I566-E568 VanDerWaalsContact C-N 3.28Å; I566-E568 PolarHBondContact O-N 2.97Å
569K97.4Very high94.5Very high2 Ų227.4 Ų27.41%0.00914%0.14CC..Hα-helixtrans-88.2-39.2178.6-56.4174.3-149.2178.80112L500 L561 L564 I566 L582 L583L500-K569 HydrophobicContact CD2-CB 4.06Å; L500-K569 HydrophobicContact CD2-CG 4.35Å; L561-K569 WeakPolarHBondContact O-CE 2.82Å; L561-K569 PolarHBondContact O-NZ 3.27Å; L564-K569 HydrophobicContact CB-CG 4.37Å; L564-K569 WeakPolarHBondContact O-CE 3.32Å; L564-K569 PolarHBondContact O-NZ 2.95Å; I566-K569 HydrophobicContact CD1-CB 4.37Å; I566-K569 HydrophobicContact CD1-CD 4.13Å; I566-K569 PolarHBondContact O-N 3.03Å; I566-K569 VanDerWaalsContact O-N 3.11Å; K569-L582 PolarHBondContact O-N 3.29Å; K569-L582 VanDerWaalsContact O-N 3.07Å; K569-L583 PolarHBondContact O-N 2.96Å; K569-L583 VanDerWaalsContact O-N 3.13Å
570A96.6Very high94.3Very high2 Ų226.6 Ų26.62%0.01713%0.133CC..  trans-150.1143.9-175.100000111.9A501 I566 W567 L572 G579A501-A570 HydrophobicContact CB-CB 3.69Å; I566-A570 PolarHBondContact O-N 3.27Å; W567-A570 WeakPolarHBondContact CA-O 3.19Å; A570-L572 HydrophobicContact CB-CD2 4.36Å; A570-G579 WeakPolarHBondContact CA-O 3.34Å
571N94.4Very high94.3Very high38 Ų3825.4 Ų25.420%0.20313%0.128CC..  trans-123.989.8172.4-175.4-10.8000110T573 L574 G579 L582N571-T573 PolarHBondContact O-N 3.01Å; N571-T573 VanDerWaalsContact O-N 3.16Å; N571-T573 WeakPolarHBondContact OD1-CB 3.48Å; N571-T573 PolarHBondContact OD1-N 3.48Å; N571-T573 PolarHBondContact OD1-OG1 2.94Å; N571-L574 HydrophobicContact CB-CD1 3.88Å; N571-L574 HydrophobicContact CB-CG 4.19Å; N571-L574 WeakPolarHBondContact O-CB 3.25Å; N571-L574 PolarHBondContact O-N 3.32Å; N571-L574 VanDerWaalsContact O-N 3.1Å; N571-G579 PolarHBondContact N-O 3.39Å; N571-G579 WeakPolarHBondContact O-CA 3.36Å; N571-L582 HydrophobicContact CB-CD2 3.81Å
572L94.2Very high94.2Very high5 Ų525.8 Ų25.83%0.02613%0.13CC..THydrogen-bonded Turntrans-78.76.9-174.4-56-177.3000113.9A501 H506 R507 F510 L518 A570 E580A501-L572 HydrophobicContact CB-CD1 4.43Å; H506-L572 HydrophobicContact CB-CD1 4.3Å; R507-L572 HydrophobicContact CB-CD1 4.46Å; R507-L572 PolarHBondContact NH1-O 3.15Å; F510-L572 HydrophobicContact CB-CB 4.28Å; F510-L572 HydrophobicContact CB-CD1 3.78Å; F510-L572 HydrophobicContact CD1-CB 3.54Å; F510-L572 HydrophobicContact CE1-CB 3.96Å; F510-L572 HydrophobicContact CG-CB 3.85Å; F510-L572 HydrophobicContact CG-CD1 4.17Å; L518-L572 HydrophobicContact CD1-CD1 4.03Å; L518-L572 HydrophobicContact CD2-CD1 3.77Å; L518-L572 HydrophobicContact CD2-CG 4.48Å; A570-L572 HydrophobicContact CB-CD2 4.36Å; L572-E580 HydrophobicContact CD2-CB 4.45Å; L572-E580 HydrophobicContact CD2-CG 3.89Å
573T91Very high94.2Very high72 Ų7225.6 Ų25.644%0.44213%0.129SC..THydrogen-bonded Turntrans-78.8-24.1163.871.60000111.7F510 N571F510-T573 HydrophobicContact CE1-CG2 3.94Å; F510-T573 HydrophobicContact CZ-CG2 3.76Å; N571-T573 PolarHBondContact O-N 3.01Å; N571-T573 VanDerWaalsContact O-N 3.16Å; N571-T573 WeakPolarHBondContact OD1-CB 3.48Å; N571-T573 PolarHBondContact OD1-N 3.48Å; N571-T573 PolarHBondContact OD1-OG1 2.94Å
574L89.9Confident94.3Very high6 Ų622.5 Ų22.53%0.03111%0.108CC..SBendtrans-76.7157.6177.6-59.9173.9000111.5C257 F273 R507 N571 I578C257-L574 HydrophobicContact CB-CD2 3.96Å; F273-L574 HydrophobicContact CE2-CD1 3.97Å; F273-L574 HydrophobicContact CZ-CD1 3.73Å; R507-L574 PolarHBondContact NH1-O 3.27Å; R507-L574 PolarHBondContact NH2-O 3.39Å; N571-L574 HydrophobicContact CB-CD1 3.88Å; N571-L574 HydrophobicContact CB-CG 4.19Å; N571-L574 WeakPolarHBondContact O-CB 3.25Å; N571-L574 PolarHBondContact O-N 3.32Å; N571-L574 VanDerWaalsContact O-N 3.1Å; L574-I578 HydrophobicContact CB-CB 4.35Å; L574-I578 HydrophobicContact CB-CG2 4.12Å; L574-I578 HydrophobicContact CD1-CG2 3.71Å; L574-I578 HydrophobicContact CG-CG2 4.49Å
575P89.3Confident94.3Very high31 Ų3121.9 Ų21.920%0.20110%0.104CC..PPolyproline II helixtrans-55.4159.3177.6-26.535.4000114R507 G577 I578 G579R507-P575 PolarHBondContact NH2-O 3.46Å; P575-G577 PolarHBondContact O-N 3.07Å; P575-I578 PolarHBondContact O-N 3.03Å; P575-I578 VanDerWaalsContact O-N 3.14Å; P575-G579 PolarHBondContact O-N 3.24Å; P575-G579 VanDerWaalsContact O-N 3.09Å
576R89.7Confident94.3Very high151 Ų15121.5 Ų21.557%0.5710%0.101SC*.THydrogen-bonded Turntrans-61.6132.5175.6-172.4-175.4176-176.4-2.3110.1E580 P600 K601R576-E580 WeakPolarHBondContact CA-OE2 3.17Å; R576-P600 HydrophobicContact CG-CB 4.2Å; R576-K601 PolarHBondContact NH2-O 2.97Å
577G86.2Confident94.4Very high0 Ų021.5 Ų21.50%010%0.102CC..THydrogen-bonded Turntrans93.8-3.4-175.500000114P575 E580 R585P575-G577 PolarHBondContact O-N 3.07Å; G577-E580 PolarHBondContact N-OE2 3.26Å; G577-R585 WeakPolarHBondContact O-CD 3.27Å; G577-R585 PolarHBondContact O-NE 3.12Å; G577-R585 PolarHBondContact O-NH1 3.09Å
578I89.6Confident94.6Very high1 Ų118.7 Ų18.71%0.0059%0.091CC..THydrogen-bonded Turntrans-121.6-53.5170.2-57.9-65.7000109.9P265 T269 L270 L574 P575 L582 R585 L598P265-I578 HydrophobicContact CB-CD1 3.64Å; P265-I578 HydrophobicContact CB-CG1 3.43Å; P265-I578 VanDerWaalsContact CB-CG1 3.43Å; T269-I578 HydrophobicContact CG2-CG2 4.14Å; L270-I578 HydrophobicContact CD2-CD1 4.28Å; L270-I578 HydrophobicContact CD2-CG2 4.01Å; L270-I578 HydrophobicContact CG-CD1 4.16Å; L574-I578 HydrophobicContact CB-CB 4.35Å; L574-I578 HydrophobicContact CB-CG2 4.12Å; L574-I578 HydrophobicContact CD1-CG2 3.71Å; L574-I578 HydrophobicContact CG-CG2 4.49Å; P575-I578 PolarHBondContact O-N 3.03Å; P575-I578 VanDerWaalsContact O-N 3.14Å; I578-L582 HydrophobicContact CG2-CD1 4.45Å; I578-R585 WeakPolarHBondContact O-CD 3.37Å; I578-L598 HydrophobicContact CD1-CD2 3.45Å; I578-L598 VanDerWaalsContact CD1-CD2 3.45Å
579G93.1Very high94.7Very high0 Ų016.7 Ų16.70%08%0.082CC..SBendtrans-67.9-40.5-170.100000114.9A570 N571 P575A570-G579 WeakPolarHBondContact CA-O 3.34Å; N571-G579 PolarHBondContact N-O 3.39Å; N571-G579 WeakPolarHBondContact O-CA 3.36Å; P575-G579 PolarHBondContact O-N 3.24Å; P575-G579 VanDerWaalsContact O-N 3.09Å
580E95.4Very high94.6Very high7 Ų719.9 Ų19.93%0.03310%0.097CC..THydrogen-bonded Turntrans-70.9134.2175.6-57.887172.300110.5R507 L572 R576 G577 L582 R585R507-E580 IonicContact CZ-OE1 2.82Å; R507-E580 IonicContact NE-OE1 2.82Å; R507-E580 PolarHBondContact NE-OE1 2.81Å; R507-E580 IonicContact NH2-OE1 2.79Å; R507-E580 PolarHBondContact NH2-OE1 3.3Å; R507-E580 IonicContact NH2-OE2 3.22Å; R507-E580 PolarHBondContact NH2-OE2 3.11Å; R507-E580 VanDerWaalsContact NH2-OE2 3.16Å; L572-E580 HydrophobicContact CD2-CB 4.45Å; L572-E580 HydrophobicContact CD2-CG 3.89Å; R576-E580 WeakPolarHBondContact CA-OE2 3.17Å; G577-E580 PolarHBondContact N-OE2 3.26Å; E580-L582 PolarHBondContact O-N 3.03Å; E580-R585 PolarHBondContact O-NE 3.31Å
581K97.4Very high94.7Very high3 Ų320.2 Ų20.21%0.01310%0.099CC..THydrogen-bonded Turntrans56.435.7179.9-43.9-177.7177.9-175.30113.8I330 D331 D497 L500 G502 L583 L584 R585I330-K581 HydrophobicContact CG2-CD 4.24Å; D331-K581 IonicContact OD1-NZ 3.96Å; D331-K581 PolarHBondContact OD1-NZ 2.7Å; D331-K581 IonicContact OD2-NZ 2.67Å; D331-K581 PolarHBondContact OD2-NZ 3.39Å; D497-K581 WeakPolarHBondContact OD1-CE 3.15Å; D497-K581 IonicContact OD1-NZ 2.72Å; D497-K581 PolarHBondContact OD1-NZ 2.61Å; D497-K581 IonicContact OD2-NZ 3.21Å; D497-K581 PolarHBondContact OD2-NZ 3.4Å; D497-K581 VanDerWaalsContact OD2-NZ 3.13Å; L500-K581 HydrophobicContact CB-CB 4.08Å; L500-K581 HydrophobicContact CB-CG 3.99Å; L500-K581 VanDerWaalsContact O-CA 3.25Å; L500-K581 WeakPolarHBondContact O-CA 3.24Å; L500-K581 PolarHBondContact O-N 3.02Å; G502-K581 VanDerWaalsContact CA-CE 3.49Å; K581-L583 VanDerWaalsContact C-N 3.28Å; K581-L583 PolarHBondContact O-N 3.49Å; K581-L584 HydrophobicContact CB-CB 4.2Å; K581-L584 HydrophobicContact CD-CD2 4.21Å; K581-L584 PolarHBondContact O-N 3.5Å; K581-R585 WeakPolarHBondContact O-CG 3.43Å; K581-R585 PolarHBondContact O-N 3.3Å
582L97.6Very high94.8Very high9 Ų920.3 Ų20.35%0.04711%0.108CC..Hα-helixtrans-50.5-47.3-175.7-179.260.7000112L270 F273 K569 N571 I578 E580 L584 R585 L586L270-L582 HydrophobicContact CD2-CD1 3.81Å; F273-L582 HydrophobicContact CD2-CD1 4.5Å; F273-L582 HydrophobicContact CE1-CD2 4.26Å; F273-L582 HydrophobicContact CZ-CD2 4.4Å; K569-L582 PolarHBondContact O-N 3.29Å; K569-L582 VanDerWaalsContact O-N 3.07Å; N571-L582 HydrophobicContact CB-CD2 3.81Å; I578-L582 HydrophobicContact CG2-CD1 4.45Å; E580-L582 PolarHBondContact O-N 3.03Å; L582-L584 VanDerWaalsContact C-N 3.33Å; L582-L584 PolarHBondContact O-N 3.15Å; L582-R585 WeakPolarHBondContact O-CB 3.34Å; L582-R585 PolarHBondContact O-N 3.48Å; L582-R585 VanDerWaalsContact O-N 3.08Å; L582-L586 HydrophobicContact CD1-CD1 4.08Å; L582-L586 HydrophobicContact CD1-CG 4.11Å; L582-L586 HydrophobicContact CG-CD1 3.94Å; L582-L586 HydrophobicContact CG-CG 4.39Å; L582-L586 WeakPolarHBondContact O-CG 3.39Å; L582-L586 PolarHBondContact O-N 2.87Å
583L98.5Very high94.9Very high4 Ų420 Ų202%0.02111%0.107CC..Hα-helixtrans-57-43.6177.9178.859.7000112.7V282 I283 F286 L500 F560 L561 L564 K569 K581 L586 A587V282-L583 HydrophobicContact CG1-CD1 3.98Å; I283-L583 HydrophobicContact CG1-CD1 3.88Å; F286-L583 HydrophobicContact CB-CD1 4.28Å; F286-L583 HydrophobicContact CB-CD2 4.3Å; F286-L583 HydrophobicContact CB-CG 4.39Å; F286-L583 HydrophobicContact CD1-CD1 4.32Å; F286-L583 HydrophobicContact CD1-CD2 4.18Å; F286-L583 HydrophobicContact CD1-CG 3.81Å; F286-L583 HydrophobicContact CD2-CD2 4.3Å; F286-L583 HydrophobicContact CE1-CG 4.28Å; F286-L583 HydrophobicContact CG-CD1 4.48Å; F286-L583 HydrophobicContact CG-CD2 3.99Å; F286-L583 HydrophobicContact CG-CG 4.08Å; L500-L583 HydrophobicContact CD2-CB 4.46Å; L500-L583 HydrophobicContact CD2-CD2 4.39Å; F560-L583 HydrophobicContact CE1-CD2 4.36Å; L561-L583 HydrophobicContact CD2-CD2 3.8Å; L564-L583 HydrophobicContact CD1-CD2 3.75Å; K569-L583 PolarHBondContact O-N 2.96Å; K569-L583 VanDerWaalsContact O-N 3.13Å; K581-L583 VanDerWaalsContact C-N 3.28Å; K581-L583 PolarHBondContact O-N 3.49Å; L583-L586 PolarHBondContact O-N 2.65Å; L583-A587 WeakPolarHBondContact O-CB 3.44Å; L583-A587 PolarHBondContact O-N 3.45Å
584L98.6Very high95Very high0 Ų019.3 Ų19.30%010%0.103CC..Hα-helixtrans-71.1-30.8177.7-17965.8000112.6F286 I330 D331 V334 A496 L500 F552 K581 L582 A588F286-L584 HydrophobicContact CE1-CB 4.28Å; F286-L584 HydrophobicContact CE1-CD1 3.87Å; F286-L584 HydrophobicContact CZ-CD1 4.29Å; I330-L584 HydrophobicContact CD1-CG 4.35Å; I330-L584 HydrophobicContact CG1-CG 4.25Å; I330-L584 HydrophobicContact CG2-CD2 4.01Å; D331-L584 WeakPolarHBondContact OD1-CD2 3.25Å; V334-L584 HydrophobicContact CB-CD1 3.97Å; V334-L584 HydrophobicContact CG1-CD1 3.84Å; V334-L584 HydrophobicContact CG2-CD1 3.76Å; V334-L584 HydrophobicContact CG2-CG 4.38Å; A496-L584 HydrophobicContact CB-CD2 4.5Å; L500-L584 HydrophobicContact CD1-CB 3.73Å; L500-L584 HydrophobicContact CD1-CD2 4.09Å; L500-L584 HydrophobicContact CD1-CG 4.45Å; F552-L584 HydrophobicContact CE1-CD1 4.06Å; F552-L584 HydrophobicContact CE1-CD2 4.36Å; F552-L584 HydrophobicContact CZ-CD1 3.94Å; F552-L584 HydrophobicContact CZ-CD2 4.07Å; K581-L584 HydrophobicContact CB-CB 4.2Å; K581-L584 HydrophobicContact CD-CD2 4.21Å; K581-L584 PolarHBondContact O-N 3.5Å; L582-L584 VanDerWaalsContact C-N 3.33Å; L582-L584 PolarHBondContact O-N 3.15Å; L584-A588 WeakPolarHBondContact O-CB 2.96Å; L584-A588 PolarHBondContact O-N 3.43Å
585R98.1Very high95.1Very high2 Ų222 Ų221%0.00813%0.125CC..Hα-helixtrans-66.6-45.4173.3-67.4-179.8-173.2-76.5-1.8111.9L270 I330 G577 I578 E580 K581 L582 A588 V589 A597 L599L270-R585 HydrophobicContact CD1-CB 4.18Å; L270-R585 HydrophobicContact CD2-CB 4.22Å; I330-R585 VanDerWaalsContact CD1-CA 3.46Å; I330-R585 HydrophobicContact CD1-CB 4.02Å; I330-R585 HydrophobicContact CD1-CG 3.48Å; I330-R585 VanDerWaalsContact CD1-CG 3.48Å; G577-R585 WeakPolarHBondContact O-CD 3.27Å; G577-R585 PolarHBondContact O-NE 3.12Å; G577-R585 PolarHBondContact O-NH1 3.09Å; I578-R585 WeakPolarHBondContact O-CD 3.37Å; E580-R585 PolarHBondContact O-NE 3.31Å; K581-R585 WeakPolarHBondContact O-CG 3.43Å; K581-R585 PolarHBondContact O-N 3.3Å; L582-R585 WeakPolarHBondContact O-CB 3.34Å; L582-R585 PolarHBondContact O-N 3.48Å; L582-R585 VanDerWaalsContact O-N 3.08Å; R585-A588 WeakPolarHBondContact O-CB 3.45Å; R585-A588 PolarHBondContact O-N 2.95Å; R585-V589 WeakPolarHBondContact O-CG2 3.38Å; R585-V589 PolarHBondContact O-N 3.08Å; R585-V589 VanDerWaalsContact O-N 3.08Å; R585-A597 WeakPolarHBondContact CD-O 3.48Å; R585-A597 WeakPolarHBondContact CG-O 3.44Å; R585-A597 PolarHBondContact NH1-O 3.09Å; R585-L599 PolarHBondContact NH1-O 2.82Å; R585-L599 PolarHBondContact NH2-O 2.97Å
586L97.8Very high95.4Very high4 Ų420.6 Ų20.62%0.02112%0.116CC..Hα-helixtrans-65.3-41.7176-62.3171.3000111.1L270 F273 L274 I279 I283 L582 L583 A588 V589 E590L270-L586 HydrophobicContact CB-CD2 3.96Å; L270-L586 HydrophobicContact CD2-CD2 3.9Å; L270-L586 HydrophobicContact CG-CD2 4.49Å; L270-L586 WeakPolarHBondContact O-CD2 3.21Å; F273-L586 HydrophobicContact CB-CD1 3.84Å; F273-L586 HydrophobicContact CB-CD2 3.74Å; F273-L586 HydrophobicContact CB-CG 4.47Å; F273-L586 HydrophobicContact CG-CD1 4.36Å; F273-L586 HydrophobicContact CG-CD2 4.44Å; L274-L586 HydrophobicContact CD2-CB 4.18Å; L274-L586 HydrophobicContact CD2-CD2 4.1Å; L274-L586 HydrophobicContact CG-CD2 4.23Å; I279-L586 HydrophobicContact CG2-CD1 3.9Å; I283-L586 HydrophobicContact CD1-CB 3.44Å; I283-L586 VanDerWaalsContact CD1-CB 3.44Å; I283-L586 HydrophobicContact CD1-CD1 3.98Å; I283-L586 HydrophobicContact CD1-CG 4.26Å; I283-L586 HydrophobicContact CG1-CB 3.88Å; L582-L586 HydrophobicContact CD1-CD1 4.08Å; L582-L586 HydrophobicContact CD1-CG 4.11Å; L582-L586 HydrophobicContact CG-CD1 3.94Å; L582-L586 HydrophobicContact CG-CG 4.39Å; L582-L586 WeakPolarHBondContact O-CG 3.39Å; L582-L586 PolarHBondContact O-N 2.87Å; L583-L586 PolarHBondContact O-N 2.65Å; L586-A588 VanDerWaalsContact C-N 3.34Å; L586-A588 PolarHBondContact O-N 3.32Å; L586-V589 PolarHBondContact O-N 3.03Å; L586-E590 PolarHBondContact O-N 3.19Å
587A98.3Very high95.7Very high1 Ų113.4 Ų13.41%0.0089%0.089CC..Hα-helixtrans-59.8-42.3172.200000112.6I283 F286 I287 L583 V589 E590 L591I283-A587 HydrophobicContact CG2-CB 4.08Å; F286-A587 HydrophobicContact CD1-CB 3.89Å; F286-A587 HydrophobicContact CE1-CB 4.22Å; I287-A587 HydrophobicContact CD1-CB 4.13Å; I287-A587 HydrophobicContact CG1-CB 3.78Å; L583-A587 WeakPolarHBondContact O-CB 3.44Å; L583-A587 PolarHBondContact O-N 3.45Å; A587-V589 VanDerWaalsContact C-N 3.3Å; A587-V589 PolarHBondContact O-N 3.18Å; A587-E590 PolarHBondContact O-N 2.99Å; A587-L591 WeakPolarHBondContact O-CB 3.25Å; A587-L591 WeakPolarHBondContact O-CG 3.46Å; A587-L591 PolarHBondContact O-N 3.07Å
588A98.1Very high96.1Very high0 Ų015.1 Ų15.10%010%0.098CC..Hα-helixtrans-59.4-41.7175.600000111.9I330 V334 L584 R585 L586 L591 G592 L593 A597I330-A588 HydrophobicContact CD1-CB 3.75Å; I330-A588 HydrophobicContact CG1-CB 3.96Å; V334-A588 HydrophobicContact CG2-CB 3.75Å; L584-A588 WeakPolarHBondContact O-CB 2.96Å; L584-A588 PolarHBondContact O-N 3.43Å; R585-A588 WeakPolarHBondContact O-CB 3.45Å; R585-A588 PolarHBondContact O-N 2.95Å; L586-A588 VanDerWaalsContact C-N 3.34Å; L586-A588 PolarHBondContact O-N 3.32Å; A588-L591 CarbonylContact O-C 3.52Å; A588-L591 WeakPolarHBondContact O-CB 3.21Å; A588-L591 PolarHBondContact O-N 3.41Å; A588-G592 PolarHBondContact O-N 2.68Å; A588-L593 HydrophobicContact CB-CB 4.09Å; A588-L593 HydrophobicContact CB-CD1 3.89Å; A588-L593 WeakPolarHBondContact O-CA 3.23Å; A588-L593 VanDerWaalsContact O-CB 3.22Å; A588-L593 WeakPolarHBondContact O-CB 3.5Å; A588-L593 PolarHBondContact O-N 3.49Å; A588-A597 HydrophobicContact CB-CB 3.99Å
589V97Very high96.2Very high12 Ų1217.9 Ų17.97%0.07311%0.113CC..Hα-helixtrans-62.4-45.8176.1176.80000111.8L270 L274 R585 L586 A587 L591 G592 L593 A597L270-V589 HydrophobicContact CB-CG2 4.4Å; L270-V589 HydrophobicContact CD1-CG2 3.85Å; L274-V589 HydrophobicContact CD1-CB 4.28Å; L274-V589 HydrophobicContact CD1-CG1 3.66Å; R585-V589 WeakPolarHBondContact O-CG2 3.38Å; R585-V589 PolarHBondContact O-N 3.08Å; R585-V589 VanDerWaalsContact O-N 3.08Å; L586-V589 PolarHBondContact O-N 3.03Å; A587-V589 VanDerWaalsContact C-N 3.3Å; A587-V589 PolarHBondContact O-N 3.18Å; V589-L591 PolarHBondContact O-N 3.17Å; V589-G592 PolarHBondContact O-N 3.29Å; V589-L593 WeakPolarHBondContact CA-O 3.22Å; V589-A597 HydrophobicContact CG2-CB 3.84Å
590E96.6Very high96.2Very high69 Ų6920.9 Ų20.932%0.32213%0.132SC..Hα-helixtrans-63.2-28.7175.1-74.1-68.2149.600112.5L274 I283 I287 L586 A587 G592L274-E590 HydrophobicContact CD2-CG 4.07Å; I283-E590 HydrophobicContact CG2-CB 4.3Å; I283-E590 HydrophobicContact CG2-CG 3.87Å; I287-E590 HydrophobicContact CD1-CB 3.76Å; L586-E590 PolarHBondContact O-N 3.19Å; A587-E590 PolarHBondContact O-N 2.99Å; E590-G592 PolarHBondContact O-N 3.16Å
591L97.3Very high96.1Very high10 Ų1022.6 Ų22.65%0.05214%0.14CC..THydrogen-bonded Turntrans-78.12.3172.9-66.3173.6000113.7I287 V334 T337 L338 R341 A587 A588 V589I287-L591 HydrophobicContact CD1-CD2 4.27Å; I287-L591 HydrophobicContact CD1-CG 4.17Å; I287-L591 HydrophobicContact CG1-CD2 4.49Å; I287-L591 HydrophobicContact CG1-CG 4.44Å; I287-L591 HydrophobicContact CG2-CD2 3.95Å; V334-L591 HydrophobicContact CB-CD1 4.46Å; V334-L591 HydrophobicContact CG1-CD1 3.8Å; V334-L591 HydrophobicContact CG2-CD1 4.29Å; T337-L591 HydrophobicContact CG2-CB 4.14Å; L338-L591 HydrophobicContact CD2-CD1 4.21Å; L338-L591 HydrophobicContact CD2-CD2 3.89Å; L338-L591 HydrophobicContact CG-CD1 4.23Å; R341-L591 VanDerWaalsContact CZ-CD2 3.43Å; A587-L591 WeakPolarHBondContact O-CB 3.25Å; A587-L591 WeakPolarHBondContact O-CG 3.46Å; A587-L591 PolarHBondContact O-N 3.07Å; A588-L591 CarbonylContact O-C 3.52Å; A588-L591 WeakPolarHBondContact O-CB 3.21Å; A588-L591 PolarHBondContact O-N 3.41Å; V589-L591 PolarHBondContact O-N 3.17Å
592G96.4Very high95.9Very high39 Ų3928.3 Ų28.340%0.40216%0.161SC..THydrogen-bonded Turntrans85.76.2179.400000114.5A588 V589 E590A588-G592 PolarHBondContact O-N 2.68Å; V589-G592 PolarHBondContact O-N 3.29Å; E590-G592 PolarHBondContact O-N 3.16Å
593L96.8Very high95.5Very high0 Ų029.4 Ų29.40%017%0.172CC..  trans-79.3148.5173.5-56.4172000110.4M333 V334 E415 V419 A588 V589M333-L593 HydrophobicContact CB-CD1 3.91Å; M333-L593 HydrophobicContact CE-CD2 3.69Å; V334-L593 HydrophobicContact CG2-CD1 4.05Å; E415-L593 HydrophobicContact CG-CD2 3.92Å; V419-L593 HydrophobicContact CG2-CD2 4.28Å; A588-L593 HydrophobicContact CB-CB 4.09Å; A588-L593 HydrophobicContact CB-CD1 3.89Å; A588-L593 WeakPolarHBondContact O-CA 3.23Å; A588-L593 VanDerWaalsContact O-CB 3.22Å; A588-L593 WeakPolarHBondContact O-CB 3.5Å; A588-L593 PolarHBondContact O-N 3.49Å; V589-L593 WeakPolarHBondContact CA-O 3.22Å
594T92.9Very high95.2Very high57 Ų5732.1 Ų32.135%0.3519%0.185SC..  trans-128.7-83.1-171.860.20000110.7E415 S596 A597E415-T594 VanDerWaalsContact OE1-CA 3.28Å; E415-T594 WeakPolarHBondContact OE1-CA 3.43Å; E415-T594 WeakPolarHBondContact OE1-CB 3.47Å; E415-T594 PolarHBondContact OE1-N 3.36Å; E415-T594 PolarHBondContact OE1-OG1 3.14Å; T594-S596 VanDerWaalsContact C-N 3.33Å; T594-S596 PolarHBondContact O-N 3.16Å; T594-A597 WeakPolarHBondContact O-CB 3.35Å; T594-A597 PolarHBondContact O-N 2.82Å; T594-A597 VanDerWaalsContact O-N 3.11Å
595A93.1Very high94.8Very high61 Ų6133 Ų3350%0.50419%0.189SC..Hα-helixtrans-61-42.3-174.800000111.6E415 A597 L598 L599E415-A595 PolarHBondContact OE1-N 3.39Å; A595-A597 VanDerWaalsContact C-N 3.25Å; A595-A597 PolarHBondContact O-N 2.79Å; A595-L598 PolarHBondContact O-N 2.96Å; A595-L598 VanDerWaalsContact O-N 3.13Å; A595-L599 PolarHBondContact O-N 2.99Å
596S94.7Very high94.5Very high2 Ų238 Ų381%0.01421%0.211CC..Hα-helixtrans-64.1-28.2178.655.60000113.8E415 T594 L598 L599E415-S596 WeakPolarHBondContact OE2-CB 3.27Å; E415-S596 PolarHBondContact OE2-N 2.83Å; E415-S596 PolarHBondContact OE2-OG 3.07Å; T594-S596 VanDerWaalsContact C-N 3.33Å; T594-S596 PolarHBondContact O-N 3.16Å; S596-L598 PolarHBondContact O-N 3.28Å; S596-L599 PolarHBondContact O-N 3.19Å
597A95.6Very high94.2Very high0 Ų037.8 Ų37.80%021%0.21CC..Hα-helixtrans-66.2-21.2176.800000112.9L270 I330 R585 A588 V589 T594 A595L270-A597 HydrophobicContact CD1-CB 4.27Å; I330-A597 HydrophobicContact CD1-CB 4.47Å; R585-A597 WeakPolarHBondContact CD-O 3.48Å; R585-A597 WeakPolarHBondContact CG-O 3.44Å; R585-A597 PolarHBondContact NH1-O 3.09Å; A588-A597 HydrophobicContact CB-CB 3.99Å; V589-A597 HydrophobicContact CG2-CB 3.84Å; T594-A597 WeakPolarHBondContact O-CB 3.35Å; T594-A597 PolarHBondContact O-N 2.82Å; T594-A597 VanDerWaalsContact O-N 3.11Å; A595-A597 VanDerWaalsContact C-N 3.25Å; A595-A597 PolarHBondContact O-N 2.79Å
598L94.3Very high94Very high37 Ų3737.8 Ų37.819%0.19421%0.21CC..Hα-helixtrans-102.7-6.2-178.9-59.1174.4000113.1R267 L270 I578 A595 S596 P600R267-L598 HydrophobicContact CB-CD1 4.44Å; L270-L598 HydrophobicContact CD1-CD2 3.65Å; L270-L598 HydrophobicContact CG-CD2 4.21Å; I578-L598 HydrophobicContact CD1-CD2 3.45Å; I578-L598 VanDerWaalsContact CD1-CD2 3.45Å; A595-L598 PolarHBondContact O-N 2.96Å; A595-L598 VanDerWaalsContact O-N 3.13Å; S596-L598 PolarHBondContact O-N 3.28Å; L598-P600 VanDerWaalsContact O-CD 3.31Å; L598-P600 WeakPolarHBondContact O-CD 2.94Å
599L93.1Very high93.8Very high58 Ų5843.2 Ų43.230%0.30423%0.23SC..PPolyproline II helixtrans-67.9124.8-177.3-72.3177.5000111.3T408 R585 A595 S596T408-L599 HydrophobicContact CG2-CD1 4.03Å; T408-L599 HydrophobicContact CG2-CD2 4.45Å; R585-L599 PolarHBondContact NH1-O 2.82Å; R585-L599 PolarHBondContact NH2-O 2.97Å; A595-L599 PolarHBondContact O-N 2.99Å; S596-L599 PolarHBondContact O-N 3.19Å
600P92.9Very high93.5Very high63 Ų6343.1 Ų43.141%0.40923%0.229SC..PPolyproline II helixtrans-61.2144.7171.5-25.336.1000111.6R576 L598 R602R576-P600 HydrophobicContact CG-CB 4.2Å; L598-P600 VanDerWaalsContact O-CD 3.31Å; L598-P600 WeakPolarHBondContact O-CD 2.94Å; P600-R602 PolarHBondContact O-N 2.77Å
601K93.2Very high93Very high44 Ų4441.7 Ų41.719%0.19123%0.229CC..PPolyproline II helixtrans-59.1130.5173.4-172.1-148.8168.454.60110.3D497 G502 Y503 R576D497-K601 VanDerWaalsContact OD1-CD 3.24Å; D497-K601 WeakPolarHBondContact OD1-CD 3.46Å; D497-K601 WeakPolarHBondContact OD1-CE 3.46Å; D497-K601 IonicContact OD1-NZ 3.61Å; D497-K601 PolarHBondContact OD1-NZ 3.13Å; D497-K601 IonicContact OD2-NZ 3.37Å; D497-K601 PolarHBondContact OD2-NZ 3.04Å; G502-K601 WeakPolarHBondContact O-CD 3.23Å; Y503-K601 HydrophobicContact CD1-CD 4.32Å; R576-K601 PolarHBondContact NH2-O 2.97Å
602R92.6Very high92.3Very high122 Ų12248.7 Ų48.746%0.4626%0.259SS..  trans-119.5135.9162.5-171.7175.3-67.5129.7-6108.9P404 P600 F606 G607P404-R602 VanDerWaalsContact CB-CZ 3.44Å; P600-R602 PolarHBondContact O-N 2.77Å; R602-F606 HydrophobicContact CG-CB 4.29Å; R602-G607 VanDerWaalsContact CD-CA 3.44Å
603A90.2Very high91.4Very high33 Ų3347.9 Ų47.927%0.27325%0.245SC..  trans-75.5142.2174.100000110Q605 F606 G607A603-Q605 PolarHBondContact O-N 3.32Å; A603-Q605 VanDerWaalsContact O-N 3.15Å; A603-F606 HydrophobicContact CB-CD2 3.86Å; A603-F606 HydrophobicContact CB-CE2 4.27Å; A603-F606 PolarHBondContact O-N 3.03Å; A603-G607 PolarHBondContact O-N 3.13Å
604M91.7Very high90Very high61 Ų6149.8 Ų49.830%0.325%0.254SS..Hα-helixtrans-51.9-41.3-174.2-176.6-177.5-75.900112.6A463 V464 F606 G607 S608A463-M604 HydrophobicContact CB-CG 4.06Å; A463-M604 HydrophobicContact CB-SD 3.74Å; V464-M604 HydrophobicContact CG2-CE 4.5Å; V464-M604 HydrophobicContact CG2-SD 3.95Å; M604-F606 PolarHBondContact O-N 3.06Å; M604-F606 VanDerWaalsContact O-N 3.16Å; M604-G607 PolarHBondContact O-N 2.86Å; M604-G607 VanDerWaalsContact O-N 3.15Å; M604-S608 WeakPolarHBondContact O-CB 3.46Å; M604-S608 PolarHBondContact O-N 2.88Å; M604-S608 PolarHBondContact O-OG 2.84Å
605Q90Very high88.5Confident17 Ų1756.9 Ų56.98%0.07928%0.28CS..Hα-helixtrans-61.1-27.8-179.671.2-175.65.800114.5A603 I610 A611A603-Q605 PolarHBondContact O-N 3.32Å; A603-Q605 VanDerWaalsContact O-N 3.15Å; Q605-I610 HydrophobicContact CB-CG2 3.95Å; Q605-I610 WeakPolarHBondContact O-CG2 3.18Å; Q605-I610 PolarHBondContact O-N 3.44Å; Q605-A611 HydrophobicContact CB-CB 4.23Å; Q605-A611 HydrophobicContact CG-CB 4.25Å; Q605-A611 WeakPolarHBondContact O-CB 3.31Å; Q605-A611 PolarHBondContact O-N 2.97Å; Q605-A611 VanDerWaalsContact O-N 3.07Å
606F91.9Very high87.1Confident108 Ų10858.2 Ų58.247%0.47428%0.279SS..Hα-helixtrans-91.1-33.9176.5-57.9-59.7000111.5R602 A603 M604 R609 A611R602-F606 HydrophobicContact CG-CB 4.29Å; A603-F606 HydrophobicContact CB-CD2 3.86Å; A603-F606 HydrophobicContact CB-CE2 4.27Å; A603-F606 PolarHBondContact O-N 3.03Å; M604-F606 PolarHBondContact O-N 3.06Å; M604-F606 VanDerWaalsContact O-N 3.16Å; F606-R609 PolarHBondContact O-N 3.44Å; F606-A611 HydrophobicContact CD1-CB 4.04Å; F606-A611 HydrophobicContact CE1-CB 4.12Å
607G92.4Very high86.2Confident0 Ų066.6 Ų66.60%032%0.324CS..Hα-helixtrans-71.4-40.9-179.500000113.9P404 D405 R602 A603 M604 R609P404-G607 VanDerWaalsContact CD-O 3.27Å; P404-G607 WeakPolarHBondContact CD-O 3.44Å; D405-G607 PolarHBondContact N-O 3.35Å; D405-G607 WeakPolarHBondContact OD1-CA 3.35Å; D405-G607 WeakPolarHBondContact OD2-CA 3.44Å; R602-G607 VanDerWaalsContact CD-CA 3.44Å; A603-G607 PolarHBondContact O-N 3.13Å; M604-G607 PolarHBondContact O-N 2.86Å; M604-G607 VanDerWaalsContact O-N 3.15Å; G607-R609 VanDerWaalsContact C-N 3.28Å
608S93.4Very high85.6Confident0 Ų069.8 Ų69.80%034%0.338CS..SBendtrans-78.6-11.8173.873.80000113.5F356 M604 I610F356-S608 WeakPolarHBondContact CB-O 3.09Å; F356-S608 WeakPolarHBondContact CD2-OG 3.45Å; F356-S608 PolarHBondContact N-O 3.48Å; M604-S608 WeakPolarHBondContact O-CB 3.46Å; M604-S608 PolarHBondContact O-N 2.88Å; M604-S608 PolarHBondContact O-OG 2.84Å; S608-I610 VanDerWaalsContact C-N 3.34Å; S608-I610 PolarHBondContact O-N 2.87Å; S608-I610 PolarHBondContact OG-N 2.97Å
609R93.3Very high85.2Confident114 Ų11475 Ų7543%0.4336%0.359SS..SBendtrans68.29.7-173.4-65.6-167.3-176.9179.22.9117.3S402 V403 F606 G607 A611 K612 M613S402-R609 PolarHBondContact O-NH2 3.4Å; S402-R609 VanDerWaalsContact O-NH2 3.11Å; V403-R609 HydrophobicContact CB-CG 4Å; V403-R609 HydrophobicContact CG1-CB 4.27Å; V403-R609 HydrophobicContact CG1-CG 3.96Å; F606-R609 PolarHBondContact O-N 3.44Å; G607-R609 VanDerWaalsContact C-N 3.28Å; R609-A611 VanDerWaalsContact C-N 3.28Å; R609-A611 PolarHBondContact O-N 2.65Å; R609-K612 PolarHBondContact O-N 3.1Å; R609-M613 PolarHBondContact O-N 3.2Å
610I91.6Very high84.7Confident10 Ų1074.4 Ų74.45%0.05136%0.363CS..Hα-helixtrans-54.7-42.5175.2-173.7167.6000112.8F356 L437 C462 Q605 S608 K612 M613F356-I610 HydrophobicContact CB-CB 4.44Å; F356-I610 HydrophobicContact CD1-CB 4.2Å; F356-I610 HydrophobicContact CD1-CD1 4.33Å; F356-I610 HydrophobicContact CD1-CG1 4.22Å; F356-I610 HydrophobicContact CD2-CB 3.6Å; F356-I610 HydrophobicContact CD2-CG1 4.43Å; F356-I610 HydrophobicContact CD2-CG2 4.46Å; F356-I610 HydrophobicContact CE1-CB 4.39Å; F356-I610 HydrophobicContact CE1-CD1 3.82Å; F356-I610 HydrophobicContact CE1-CG1 4.21Å; F356-I610 HydrophobicContact CE2-CB 3.81Å; F356-I610 HydrophobicContact CE2-CD1 4.15Å; F356-I610 HydrophobicContact CE2-CG1 4.41Å; F356-I610 HydrophobicContact CE2-CG2 4.42Å; F356-I610 HydrophobicContact CG-CB 3.81Å; F356-I610 HydrophobicContact CG-CG1 4.33Å; F356-I610 HydrophobicContact CZ-CB 4.21Å; F356-I610 HydrophobicContact CZ-CD1 3.71Å; F356-I610 HydrophobicContact CZ-CG1 4.3Å; L437-I610 HydrophobicContact CD1-CD1 4.17Å; L437-I610 HydrophobicContact CD2-CD1 4Å; L437-I610 HydrophobicContact CD2-CG1 3.99Å; C462-I610 HydrophobicContact CB-CD1 3.47Å; C462-I610 VanDerWaalsContact CB-CD1 3.47Å; Q605-I610 HydrophobicContact CB-CG2 3.95Å; Q605-I610 WeakPolarHBondContact O-CG2 3.18Å; Q605-I610 PolarHBondContact O-N 3.44Å; S608-I610 VanDerWaalsContact C-N 3.34Å; S608-I610 PolarHBondContact O-N 2.87Å; S608-I610 PolarHBondContact OG-N 2.97Å; I610-K612 PolarHBondContact O-N 2.63Å; I610-K612 VanDerWaalsContact O-N 3.09Å; I610-M613 WeakPolarHBondContact O-CB 3.41Å; I610-M613 PolarHBondContact O-N 3.22Å
611A86.1Confident84.5Confident39 Ų3975.9 Ų75.932%0.32238%0.375SS..Hα-helixtrans-65.6-16.5-178.500000113.9Q605 F606 R609Q605-A611 HydrophobicContact CB-CB 4.23Å; Q605-A611 HydrophobicContact CG-CB 4.25Å; Q605-A611 WeakPolarHBondContact O-CB 3.31Å; Q605-A611 PolarHBondContact O-N 2.97Å; Q605-A611 VanDerWaalsContact O-N 3.07Å; F606-A611 HydrophobicContact CD1-CB 4.04Å; F606-A611 HydrophobicContact CE1-CB 4.12Å; R609-A611 VanDerWaalsContact C-N 3.28Å; R609-A611 PolarHBondContact O-N 2.65Å
612K82.1Confident84.4Confident158 Ų15876.6 Ų76.669%0.68738%0.381SS*.Hα-helixtrans-100.5-9.5176.6-71.3-169.4175.1-172.30112.9R609 I610R609-K612 PolarHBondContact O-N 3.1Å; I610-K612 PolarHBondContact O-N 2.63Å; I610-K612 VanDerWaalsContact O-N 3.09Å
613M77.9Confident84.2Confident21 Ų2176.2 Ų76.210%0.10338%0.382CS..Hα-helixtrans-70.1-40.6-171.8-140.8177.943.400110.5F356 M434 L437 R609 I610F356-M613 HydrophobicContact CB-CE 4.28Å; F356-M613 HydrophobicContact CB-SD 3.65Å; F356-M613 HydrophobicContact CD1-CE 3.81Å; F356-M613 HydrophobicContact CD1-SD 4.23Å; F356-M613 HydrophobicContact CG-CE 4.48Å; F356-M613 HydrophobicContact CG-SD 4.43Å; M434-M613 HydrophobicContact CB-CE 4.36Å; M434-M613 HydrophobicContact CB-SD 4.41Å; M434-M613 HydrophobicContact CE-CB 3.77Å; M434-M613 HydrophobicContact CE-CE 3.96Å; M434-M613 HydrophobicContact CE-CG 3.44Å; M434-M613 VanDerWaalsContact CE-CG 3.44Å; M434-M613 WeakPolarHBondContact CE-O 3.48Å; M434-M613 HydrophobicContact CE-SD 4.19Å; M434-M613 HydrophobicContact SD-CE 3.71Å; M434-M613 HydrophobicContact SD-CG 4.44Å; L437-M613 HydrophobicContact CB-CE 3.75Å; L437-M613 HydrophobicContact CD2-CE 3.12Å; L437-M613 HydrophobicContact CG-CE 4.02Å; R609-M613 PolarHBondContact O-N 3.2Å; I610-M613 WeakPolarHBondContact O-CB 3.41Å; I610-M613 PolarHBondContact O-N 3.22Å
614E67.5Low84.2Confident41 Ų4174.7 Ų74.719%0.19237%0.37CS..SBendtrans-108.1105.7176.4-63.9-179.213300108.9M434 Q438 R441 N616 R626M434-E614 HydrophobicContact CE-CG 3.47Å; M434-E614 VanDerWaalsContact CE-CG 3.47Å; M434-E614 HydrophobicContact SD-CG 3.66Å; Q438-E614 WeakPolarHBondContact CG-OE1 3.41Å; Q438-E614 PolarHBondContact NE2-OE1 2.92Å; R441-E614 IonicContact CZ-OE1 3.19Å; R441-E614 IonicContact CZ-OE2 3.81Å; R441-E614 VanDerWaalsContact CZ-OE2 3.24Å; R441-E614 IonicContact NH1-OE1 2.84Å; R441-E614 IonicContact NH1-OE2 3.81Å; R441-E614 PolarHBondContact NH1-OE2 3.44Å; R441-E614 VanDerWaalsContact NH2-CD 3.27Å; R441-E614 IonicContact NH2-OE1 2.68Å; R441-E614 PolarHBondContact NH2-OE1 2.81Å; R441-E614 IonicContact NH2-OE2 2.85Å; R441-E614 PolarHBondContact NH2-OE2 2.96Å; E614-N616 VanDerWaalsContact C-N 3.33Å; E614-N616 PolarHBondContact O-N 3.16Å; E614-R626 VanDerWaalsContact OE2-CD 3.25Å; E614-R626 WeakPolarHBondContact OE2-CD 3.44Å; E614-R626 IonicContact OE2-NE 3.98Å
615K60.3Low83.8Confident206 Ų20673.8 Ų73.890%0.89638%0.376SS*.  trans-69.682.3-178.4-72.5-176.5180178.40111.4
616N64.9Low83.7Confident89 Ų8974.9 Ų74.948%0.47638%0.379SS..  trans-119143.9172.9-66-7000110.6E614 E618 R626E614-N616 VanDerWaalsContact C-N 3.33Å; E614-N616 PolarHBondContact O-N 3.16Å; N616-E618 HydrophobicContact CB-CG 4.12Å; N616-E618 WeakPolarHBondContact CB-OE2 2.97Å; N616-E618 PolarHBondContact ND2-OE2 2.79Å; N616-E618 PolarHBondContact O-N 2.8Å; N616-R626 PolarHBondContact ND2-NH1 2.97Å
617N74.4Confident83.3Confident178 Ų17869.9 Ų69.995%0.95236%0.358SS*.  trans-78.727.9176-75.6-13.1000113
618E83.3Confident82.5Confident67 Ų6774.8 Ų74.831%0.31338%0.381SS..  trans-82.5140.8-178.2-66.1164111.500111V455 N616 R626V455-E618 HydrophobicContact CG2-CB 4Å; N616-E618 HydrophobicContact CB-CG 4.12Å; N616-E618 WeakPolarHBondContact CB-OE2 2.97Å; N616-E618 PolarHBondContact ND2-OE2 2.79Å; N616-E618 PolarHBondContact O-N 2.8Å; E618-R626 IonicContact OE1-NH1 3.87Å; E618-R626 IonicContact OE2-CZ 3.63Å; E618-R626 IonicContact OE2-NH1 2.95Å; E618-R626 PolarHBondContact OE2-NH1 3.43Å
619K85.4Confident81.2Confident146 Ų14679 Ų7964%0.63540%0.402SS*.  trans-82.3154.2172.3-58.3176.2-179.2174.30109.8S621 D622K619-S621 PolarHBondContact O-N 3.31Å; K619-S621 VanDerWaalsContact O-N 3.13Å; K619-D622 WeakPolarHBondContact CB-OD2 3.36Å; K619-D622 PolarHBondContact N-OD2 3.32Å; K619-D622 WeakPolarHBondContact O-CB 3.18Å; K619-D622 PolarHBondContact O-N 2.87Å
620A84.2Confident79.3Confident46 Ų4679.1 Ų79.138%0.3841%0.41SS..THydrogen-bonded Turntrans-56.9-31.2178.900000113.6L456L456-A620 HydrophobicContact CB-CB 4.18Å; L456-A620 WeakPolarHBondContact CB-O 3.37Å; L456-A620 PolarHBondContact N-O 3.22Å
621S88.9Confident77.1Confident93 Ų9380.9 Ų80.965%0.6542%0.423SS*.THydrogen-bonded Turntrans-82.7-10.7178.353.70000114.4K619K619-S621 PolarHBondContact O-N 3.31Å; K619-S621 VanDerWaalsContact O-N 3.13Å
622D90.4Very high74.8Confident60 Ų6086.1 Ų86.132%0.32145%0.445SS..SBendtrans-71.5148.5-176.3-62.9-13.9000109.8T454 V455 K619 C624T454-D622 CarbonylContact C-O 3.46Å; T454-D622 VanDerWaalsContact CA-O 3.25Å; T454-D622 WeakPolarHBondContact CA-O 3.46Å; V455-D622 PolarHBondContact N-O 3.4Å; K619-D622 WeakPolarHBondContact CB-OD2 3.36Å; K619-D622 PolarHBondContact N-OD2 3.32Å; K619-D622 WeakPolarHBondContact O-CB 3.18Å; K619-D622 PolarHBondContact O-N 2.87Å; D622-C624 PolarHBondContact O-N 3.48Å
623K89.2Confident72.8Confident113 Ų11385.8 Ų85.849%0.49145%0.446SS..BIsolated β-bridgetrans-62.2125.8173.3-161.7-176.8-164.4-178.60109.1D453 G625D453-K623 WeakPolarHBondContact OD2-CE 3.4Å; D453-K623 IonicContact OD2-NZ 3.66Å; K623-G625 PolarHBondContact O-N 2.88Å
624C88.6Confident70.8Confident1 Ų189 Ų891%0.00746%0.464CS..  trans-82.2105.6-176.8-172.80000110.7D453 V455 D458 D622 R626 L627D453-C624 WeakPolarHBondContact O-CB 3.38Å; D453-C624 PolarHBondContact O-N 2.92Å; V455-C624 HydrophobicContact CG2-CB 4.05Å; D458-C624 HydrophobicContact CB-CB 4.3Å; D622-C624 PolarHBondContact O-N 3.48Å; C624-R626 PolarHBondContact O-N 3.31Å; C624-R626 VanDerWaalsContact O-N 3.16Å; C624-R626 VanDerWaalsContact SG-CZ 3.55Å; C624-R626 PolarHBondContact SG-NH2 3.43Å; C624-R626 VanDerWaalsContact SG-NH2 3.39Å; C624-L627 HydrophobicContact CB-CD1 4.01Å; C624-L627 HydrophobicContact CB-CG 4.06Å; C624-L627 PolarHBondContact O-N 2.87Å
625G84.9Confident69.3Low42 Ų4291.4 Ų91.443%0.43348%0.477SS..G310 helixtrans-60.4-23.1174.100000113.5K623 L627 Q628K623-G625 PolarHBondContact O-N 2.88Å; G625-L627 VanDerWaalsContact C-N 3.29Å; G625-L627 PolarHBondContact O-N 2.92Å; G625-Q628 WeakPolarHBondContact O-CB 3.26Å; G625-Q628 PolarHBondContact O-N 2.83Å
626R87.1Confident68Low41 Ų4185 Ų8516%0.15546%0.459CS..G310 helixtrans-74.3-16.9-177.8-54.5178-64.7-87.2-0.5114R441 D458 E614 N616 E618 C624 Q628R441-R626 VanDerWaalsContact NH1-CD 3.27Å; R441-R626 VanDerWaalsContact NH1-NE 3.19Å; D458-R626 IonicContact OD2-CZ 2.86Å; D458-R626 IonicContact OD2-NE 2.91Å; D458-R626 PolarHBondContact OD2-NE 2.84Å; D458-R626 IonicContact OD2-NH2 2.6Å; D458-R626 PolarHBondContact OD2-NH2 3.38Å; E614-R626 VanDerWaalsContact OE2-CD 3.25Å; E614-R626 WeakPolarHBondContact OE2-CD 3.44Å; E614-R626 IonicContact OE2-NE 3.98Å; N616-R626 PolarHBondContact ND2-NH1 2.97Å; E618-R626 IonicContact OE1-NH1 3.87Å; E618-R626 IonicContact OE2-CZ 3.63Å; E618-R626 IonicContact OE2-NH1 2.95Å; E618-R626 PolarHBondContact OE2-NH1 3.43Å; C624-R626 PolarHBondContact O-N 3.31Å; C624-R626 VanDerWaalsContact O-N 3.16Å; C624-R626 VanDerWaalsContact SG-CZ 3.55Å; C624-R626 PolarHBondContact SG-NH2 3.43Å; C624-R626 VanDerWaalsContact SG-NH2 3.39Å; R626-Q628 VanDerWaalsContact C-N 3.35Å
627L84.3Confident66.7Low3 Ų386 Ų862%0.01646%0.462CS..G310 helixtrans-87-6.1174.6-64178.4000112.6Q162 R441 C446 I449 D458 C624 G625Q162-L627 PolarHBondContact NE2-O 3.13Å; R441-L627 HydrophobicContact CG-CD2 4.31Å; C446-L627 HydrophobicContact CB-CD2 4.26Å; I449-L627 HydrophobicContact CD1-CD1 4.46Å; I449-L627 HydrophobicContact CD1-CD2 3.79Å; I449-L627 HydrophobicContact CG2-CD1 4.01Å; D458-L627 HydrophobicContact CB-CD1 3.98Å; D458-L627 HydrophobicContact CB-CD2 4.17Å; D458-L627 HydrophobicContact CB-CG 4.08Å; D458-L627 WeakPolarHBondContact OD1-CD2 3.2Å; C624-L627 HydrophobicContact CB-CD1 4.01Å; C624-L627 HydrophobicContact CB-CG 4.06Å; C624-L627 PolarHBondContact O-N 2.87Å; G625-L627 VanDerWaalsContact C-N 3.29Å; G625-L627 PolarHBondContact O-N 2.92Å
628Q75.8Confident64.7Low103 Ų10384.7 Ų84.748%0.48145%0.451SS..SBendtrans-85.6124.7178.6-60.4-179.27.900110.2G625 R626 I630G625-Q628 WeakPolarHBondContact O-CB 3.26Å; G625-Q628 PolarHBondContact O-N 2.83Å; R626-Q628 VanDerWaalsContact C-N 3.35Å; Q628-I630 PolarHBondContact O-N 3.47Å
629I64.5Low62.5Low88 Ų8889.6 Ų89.645%0.45147%0.471SS..  trans-75.5110.9166.4-68.4171000107.3Q162 H447 S631Q162-I629 HydrophobicContact CB-CD1 4.22Å; Q162-I629 HydrophobicContact CG-CD1 4.35Å; H447-I629 WeakPolarHBondContact CE1-CD1 3.39Å; I629-S631 PolarHBondContact O-N 3.34Å
630I53.4Low60.1Low116 Ų11690.5 Ų90.560%0.59548%0.477SS*.  trans-72.3112.3166.1-57173.2000105.5Q628 L632 N634 L635Q628-I630 PolarHBondContact O-N 3.47Å; I630-L632 PolarHBondContact O-N 2.87Å; I630-N634 HydrophobicContact CG2-CB 4.04Å; I630-L635 HydrophobicContact CG2-CD1 4.36Å
631S45.5Very low57.9Low47 Ų4793.8 Ų93.833%0.32949%0.493SS..  trans-56.4137170.366.70000108.4I629 E633 N634I629-S631 PolarHBondContact O-N 3.34Å; S631-E633 PolarHBondContact O-N 3.38Å; S631-N634 PolarHBondContact O-N 3.14Å; S631-N634 PolarHBondContact OG-ND2 3.27Å
632L39.2Very low55.6Low149 Ų14998.3 Ų98.378%0.7850%0.501SS*.Hα-helixtrans-54.7-21.1177.3-85.1142.6000112.6I630 N634 L635I630-L632 PolarHBondContact O-N 2.87Å; L632-N634 VanDerWaalsContact C-N 3.35Å; L632-N634 PolarHBondContact O-N 3.2Å; L632-L635 PolarHBondContact O-N 3.17Å
633E38.7Very low52.9Low151 Ų151106.4 Ų106.471%0.70654%0.543SS*.Hα-helixtrans-64.9-31.9173.3-67.1176.7156.700113.6S631 L635 S636S631-E633 PolarHBondContact O-N 3.38Å; E633-L635 VanDerWaalsContact C-N 3.34Å; E633-S636 PolarHBondContact O-N 2.75Å
634N36.6Very low51.1Low90 Ų90106.1 Ų106.148%0.48155%0.545SS..Hα-helixtrans-79.4-15.9179.4-76.8-29.5000113.6I630 S631 L632I630-N634 HydrophobicContact CG2-CB 4.04Å; S631-N634 PolarHBondContact O-N 3.14Å; S631-N634 PolarHBondContact OG-ND2 3.27Å; L632-N634 VanDerWaalsContact C-N 3.35Å; L632-N634 PolarHBondContact O-N 3.2Å
635L36.8Very low49.1Very low91 Ų91111.6 Ų111.648%0.47657%0.574SS.*Hα-helixtrans-77.1-24.5172.9-91.7145.1000112.4I630 L632 E633I630-L635 HydrophobicContact CG2-CD1 4.36Å; L632-L635 PolarHBondContact O-N 3.17Å; E633-L635 VanDerWaalsContact C-N 3.34Å
636S32.9Very low47.1Very low72 Ų72115.4 Ų115.450%0.50358%0.582SS.*Hα-helixtrans-71.2-39.7174.4-47.90000111.5E633 Q638 K639 E640E633-S636 PolarHBondContact O-N 2.75Å; S636-Q638 PolarHBondContact O-N 3.08Å; S636-K639 PolarHBondContact O-N 3.12Å; S636-E640 PolarHBondContact O-N 3.02Å
637I37Very low44.8Very low108 Ų108119.8 Ų119.855%0.55461%0.607SS**Hα-helixtrans-72.1-32.1-175.6-60.2172000111.8K639 T641I637-K639 VanDerWaalsContact C-N 3.33Å; I637-K639 PolarHBondContact O-N 3.26Å; I637-T641 PolarHBondContact O-OG1 3.01Å
638Q32.9Very low42.3Very low152 Ų152127.1 Ų127.171%0.7164%0.644SS**Hα-helixtrans-76.6-15.4176-80.4-169.4-10.600114.4S636S636-Q638 PolarHBondContact O-N 3.08Å
639K35.6Very low40.1Very low169 Ų169128.7 Ų128.774%0.73566%0.655SS**Hα-helixtrans-86.7-20.4173.5-82.7-174174.9-178.80113.3S636 I637S636-K639 PolarHBondContact O-N 3.12Å; I637-K639 VanDerWaalsContact C-N 3.33Å; I637-K639 PolarHBondContact O-N 3.26Å
640E34.9Very low38.3Very low165 Ų165131.6 Ų131.677%0.77167%0.669SS**Hα-helixtrans-90.9-10.6178.4-74.4-176.9163.100114.3S636S636-E640 PolarHBondContact O-N 3.02Å
641T37.9Very low37.2Very low115 Ų115132.8 Ų132.871%0.70668%0.675SS**SBendtrans-948174.914.60000114.4I637I637-T641 PolarHBondContact O-OG1 3.01Å
642K41Very low36.5Very low189 Ų189140 Ų14082%0.82270%0.704SS**  trans-127.261.9169.5-77.4-171.3177.4-178.50110.7
643L34.3Very low36.2Very low229 Ų229139.2 Ų139.2100%1.19970%0.697SS**  trans-133.20156.8-97160.9000109

Retrieved 643 of 643 residues in 4237.2 ms (Link to these results)