A0A096MYP2_PAPAN Loading...

Cysteinyl leukotriene receptor 2

AlphaFold DB , UniProt , Accession A0A096MYP2, Species PAPAN (Papio anubis, Olive baboon), Gene CYSLTR2, Length 332 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	36.2	Very low	34	Very low	215 Å²	215	173.3 Å²	173.3	100%	1.059	86%	0.859	S	S	*	*				0	71.5	0	-152.4	158.2	-171.3	0	0	106.9	H3	M1-H3 VanDerWaalsContact C-N 3.29Å
2	A	38.1	Very low	33.7	Very low	97 Å²	97	173 Å²	173	80%	0.802	86%	0.857	S	S	*	*			cis	52.5	46.3	48.9	0	0	0	0	0	111.4
3	H	34.9	Very low	33.6	Very low	154 Å²	154	167.2 Å²	167.2	71%	0.713	84%	0.844	S	S	*	*			trans	-154.1	129.9	157.1	-90	-71.3	0	0	0	106.2	M1	M1-H3 VanDerWaalsContact C-N 3.29Å
4	L	34.4	Very low	33.1	Very low	177 Å²	177	167 Å²	167	93%	0.927	85%	0.845	S	S	*	*	S	Bend	trans	102.2	21.4	-176.4	-56.8	156.5	0	0	0	116.7
5	I	39.4	Very low	33	Very low	151 Å²	151	167.2 Å²	167.2	77%	0.774	84%	0.841	S	S	*	*			trans	-103.3	85.2	140.6	-58.1	171.4	0	0	0	106
6	S	35.8	Very low	32.8	Very low	109 Å²	109	163.3 Å²	163.3	76%	0.762	83%	0.831	S	S	*	*	S	Bend	trans	-162.5	19	169.8	-163.7	0	0	0	0	116.3
7	M	32.4	Very low	33	Very low	182 Å²	182	159.8 Å²	159.8	90%	0.897	82%	0.824	S	S	*	*	S	Bend	trans	-149.2	27.7	179	-120.6	-177	84.5	0	0	118.6
8	E	33.5	Very low	32.8	Very low	194 Å²	194	159.2 Å²	159.2	91%	0.907	82%	0.821	S	S	*	*	S	Bend	trans	-145.7	19.1	162.6	-117.4	171.7	168.7	0	0	114.5	K10	E8-K10 PolarHBondContact O-N 3.45Å; E8-K10 VanDerWaalsContact O-N 3.12Å
9	R	31.4	Very low	32.7	Very low	226 Å²	226	156.3 Å²	156.3	85%	0.853	82%	0.816	S	S	*	*			trans	-85.8	66.9	165.2	-151.7	-170.2	-64.5	-173.6	1.4	109.4
10	K	31.2	Very low	32.5	Very low	192 Å²	192	155.5 Å²	155.5	84%	0.835	82%	0.818	S	S	*	*			trans	-166.2	77.8	160.5	-119.3	-178.2	-175.4	-175.8	0	110.8	E8	E8-K10 PolarHBondContact O-N 3.45Å; E8-K10 VanDerWaalsContact O-N 3.12Å
11	F	27	Very low	32.3	Very low	209 Å²	209	152.8 Å²	152.8	92%	0.917	81%	0.812	S	S	*	*				-156.2	95.4	126.2	-124.2	-87.5	0	0	0	108.6
12	M	29.8	Very low	32.1	Very low	170 Å²	170	152 Å²	152	84%	0.837	81%	0.805	S	S	*	*			trans	-70.7	155.6	167.8	-169.6	167.1	-173.7	0	0	108.7
13	S	32.3	Very low	31.8	Very low	98 Å²	98	156 Å²	156	69%	0.685	81%	0.81	S	S	*	*			trans	67.6	102.7	163.7	66.3	0	0	0	0	117.8
14	L	27.4	Very low	31.7	Very low	164 Å²	164	155.9 Å²	155.9	86%	0.859	81%	0.81	S	S	*	*				-168.2	119.4	107.7	-119.5	82.5	0	0	0	109.4
15	H	30.7	Very low	31.7	Very low	170 Å²	170	153.2 Å²	153.2	79%	0.787	80%	0.803	S	S	*	*			trans	-72.5	151	158.6	-122.2	-64.4	0	0	0	107.9	S17	H15-S17 PolarHBondContact ND1-N 3.21Å
16	P	30.5	Very low	31.5	Very low	105 Å²	105	153 Å²	153	68%	0.682	80%	0.804	S	S	*	*				-135.3	145.7	97.5	19.8	0.1	0	0	0	113.5
17	S	35.9	Very low	31.4	Very low	103 Å²	103	150.7 Å²	150.7	72%	0.72	80%	0.796	S	S	*	*			trans	-52.4	124.6	165.8	45	0	0	0	0	112.3	H15	H15-S17 PolarHBondContact ND1-N 3.21Å
18	I	29.1	Very low	31.5	Very low	149 Å²	149	148.5 Å²	148.5	76%	0.764	79%	0.793	S	S	*	*			trans	-118.1	111.4	163.7	-63.3	177.1	0	0	0	107.5	V20	I18-V20 PolarHBondContact O-N 3.24Å
19	S	31	Very low	31.5	Very low	105 Å²	105	148.2 Å²	148.2	73%	0.734	79%	0.79	S	S	*	*			trans	-60.8	115.5	167.3	50.1	0	0	0	0	109.9	S21	S19-S21 PolarHBondContact O-N 3.4Å
20	V	29.8	Very low	31.5	Very low	140 Å²	140	142 Å²	142	85%	0.848	78%	0.781	S	S	*	*			trans	-85.7	105.4	167.1	180	0	0	0	0	107.3	I18	I18-V20 PolarHBondContact O-N 3.24Å
21	S	28.6	Very low	31.7	Very low	98 Å²	98	136.8 Å²	136.8	69%	0.685	77%	0.768	S	S	*	*			trans	-60.4	131.9	171.4	-40.3	0	0	0	0	110.1	S19 M23	S19-S21 PolarHBondContact O-N 3.4Å; S21-M23 PolarHBondContact O-N 3.35Å
22	E	31.8	Very low	32	Very low	198 Å²	198	133.3 Å²	133.3	93%	0.925	76%	0.759	S	S	*	*			trans	-54.8	124.8	162.1	-74.2	172	143.6	0	0	109.2
23	M	30.1	Very low	32.3	Very low	181 Å²	181	131.9 Å²	131.9	89%	0.892	76%	0.755	S	S	*	*			trans	-121.7	100.6	165.8	-165.1	159.4	-174.3	0	0	107.2	S21 P25	S21-M23 PolarHBondContact O-N 3.35Å; M23-P25 WeakPolarHBondContact O-CD 3.32Å
24	E	33.4	Very low	32.6	Very low	153 Å²	153	133.1 Å²	133.1	72%	0.715	75%	0.754	S	S	*	*			trans	-57.2	127.8	167.2	-69.2	-163.8	144	0	0	109.8	N26	E24-N26 PolarHBondContact O-N 3.07Å; E24-N26 PolarHBondContact OE2-ND2 3.18Å
25	P	34.5	Very low	33.5	Very low	121 Å²	121	129.8 Å²	129.8	79%	0.786	74%	0.744	S	S	*	*			trans	-85.8	91.8	153.9	30.3	-19.7	0	0	0	106.7	M23 G27	M23-P25 WeakPolarHBondContact O-CD 3.32Å; P25-G27 PolarHBondContact O-N 3.12Å
26	N	34.6	Very low	34.6	Very low	147 Å²	147	131 Å²	131	79%	0.786	74%	0.742	S	S	*	*			trans	-67.9	71.2	156.8	-107.1	-29.7	0	0	0	108.4	E24	E24-N26 PolarHBondContact O-N 3.07Å; E24-N26 PolarHBondContact OE2-ND2 3.18Å
27	G	33.4	Very low	36	Very low	59 Å²	59	132.9 Å²	132.9	61%	0.608	75%	0.746	S	S	*	*			trans	-111.4	97.8	165.6	0	0	0	0	0	106.4	P25 F29	P25-G27 PolarHBondContact O-N 3.12Å; G27-F29 PolarHBondContact O-N 3.24Å
28	T	34.7	Very low	37.6	Very low	136 Å²	136	130.4 Å²	130.4	83%	0.834	73%	0.729	S	S	*	*			trans	-56.7	88.2	161.2	40.8	0	0	0	0	108	S30	T28-S30 PolarHBondContact O-N 2.96Å
29	F	33.6	Very low	40.1	Very low	189 Å²	189	127.6 Å²	127.6	83%	0.829	72%	0.719	S	S	*	*			trans	-70.6	86.6	167.4	-150	-92.8	0	0	0	105.1	G27 S31	G27-F29 PolarHBondContact O-N 3.24Å; F29-S31 PolarHBondContact O-N 3.41Å
30	S	32.3	Very low	42.7	Very low	95 Å²	95	122.9 Å²	122.9	66%	0.664	69%	0.685	S	S	*	*			trans	-59	91.1	161.1	36.5	0	0	0	0	105.9	T28 N32	T28-S30 PolarHBondContact O-N 2.96Å; S30-N32 PolarHBondContact O-N 2.93Å
31	S	35.3	Very low	45.3	Very low	82 Å²	82	118.5 Å²	118.5	57%	0.573	66%	0.655	S	S	*	*			trans	-63.7	83.2	162.3	44.6	0	0	0	0	106	F29 N33	F29-S31 PolarHBondContact O-N 3.41Å; S31-N33 PolarHBondContact O-N 3.25Å
32	N	32.7	Very low	48.2	Very low	136 Å²	136	118.5 Å²	118.5	73%	0.727	65%	0.647	S	S	*	*			trans	-62.5	75.6	155	-90.8	-13.2	0	0	0	106.3	S30 N34	S30-N32 PolarHBondContact O-N 2.93Å; N32-N34 PolarHBondContact O-N 3.42Å
33	N	37.2	Very low	51.1	Low	140 Å²	140	111.1 Å²	111.1	75%	0.749	61%	0.613	S	S	*	*			trans	-65.4	70.3	153.3	-85	-12.3	0	0	0	106.2	S31 S35	S31-N33 PolarHBondContact O-N 3.25Å; N33-S35 PolarHBondContact O-N 2.97Å
34	N	37.9	Very low	54.1	Low	124 Å²	124	103.1 Å²	103.1	66%	0.663	57%	0.573	S	S	*	*			trans	-65.1	80.2	149.2	-91.4	-12.8	0	0	0	104.9	N32 R36	N32-N34 PolarHBondContact O-N 3.42Å; N34-R36 HydrophobicContact CB-CG 4.46Å; N34-R36 PolarHBondContact O-N 2.88Å
35	S	47	Very low	57	Low	94 Å²	94	100.4 Å²	100.4	66%	0.657	56%	0.556	S	S	*	*			trans	-54.7	89	152.7	43.1	0	0	0	0	105.3	N33 N37	N33-S35 PolarHBondContact O-N 2.97Å; S35-N37 PolarHBondContact O-N 3.45Å
36	R	52.4	Low	59.8	Low	197 Å²	197	101.6 Å²	101.6	74%	0.743	55%	0.551	S	S	*	*			trans	-65.1	95.7	176.1	-74.1	-179	177.9	151.2	-1	105.5	N34 C38	N34-R36 HydrophobicContact CB-CG 4.46Å; N34-R36 PolarHBondContact O-N 2.88Å; R36-C38 PolarHBondContact O-N 3.3Å
37	N	59.8	Low	62.8	Low	143 Å²	143	97 Å²	97	77%	0.765	52%	0.524	S	S	*	.			trans	-59.4	101.3	172.8	-81.1	-17.7	0	0	0	107.3	S35 T39	S35-N37 PolarHBondContact O-N 3.45Å; N37-T39 PolarHBondContact O-N 3.4Å
38	C	70.1	Confident	65.8	Low	52 Å²	52	94.4 Å²	94.4	35%	0.351	50%	0.496	S	S	.	.			trans	-60.9	122.4	173.3	-52.1	0	0	0	0	107.5	R36 I40 C286	R36-C38 PolarHBondContact O-N 3.3Å; C38-I40 HydrophobicContact CB-CG2 3.79Å; C38-I40 PolarHBondContact O-N 3.34Å; C38-I40 VanDerWaalsContact O-N 3.08Å; C38-C286 HydrophobicContact CB-CB 3.88Å; C38-C286 WeakPolarHBondContact CB-SG 3.35Å; C38-C286 WeakPolarHBondContact SG-CB 3.3Å; C38-C286 CovalentContact SG-SG 2.04Å; C38-C286 PolarHBondContact SG-SG 2.9Å
39	T	82.3	Confident	68.8	Low	90 Å²	90	88.1 Å²	88.1	55%	0.552	46%	0.458	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.2	-10	-175.3	59.2	0	0	0	0	113.3	N37 E41 N42 F43 D288	N37-T39 PolarHBondContact O-N 3.4Å; T39-E41 VanDerWaalsContact C-N 3.33Å; T39-E41 PolarHBondContact O-N 3.39Å; T39-N42 PolarHBondContact O-N 3.45Å; T39-F43 PolarHBondContact O-N 2.88Å; T39-D288 PolarHBondContact N-OD2 3.13Å; T39-D288 PolarHBondContact OG1-OD2 2.75Å
40	I	85.1	Confident	71.8	Confident	6 Å²	6	83.3 Å²	83.3	3%	0.031	44%	0.443	C	S	.	.	H	α-helix	trans	-61.9	-33.9	-176.9	-171.4	59.2	0	0	0	114	C38 N42 F43 K44 H291 K292 V295	C38-I40 HydrophobicContact CB-CG2 3.79Å; C38-I40 PolarHBondContact O-N 3.34Å; C38-I40 VanDerWaalsContact O-N 3.08Å; I40-N42 VanDerWaalsContact C-N 3.34Å; I40-N42 PolarHBondContact O-N 3.28Å; I40-F43 HydrophobicContact CD1-CB 4.49Å; I40-F43 HydrophobicContact CD1-CD1 4.04Å; I40-F43 PolarHBondContact O-N 3.39Å; I40-K44 HydrophobicContact CD1-CG 4.48Å; I40-K44 HydrophobicContact CG1-CD 4.09Å; I40-K44 HydrophobicContact CG1-CG 4.29Å; I40-K44 WeakPolarHBondContact O-CG 3.48Å; I40-K44 PolarHBondContact O-N 2.99Å; I40-H291 HydrophobicContact CD1-CB 4.31Å; I40-H291 HydrophobicContact CG1-CB 4.08Å; I40-K292 HydrophobicContact CD1-CB 3.95Å; I40-V295 HydrophobicContact CD1-CG2 4.16Å
41	E	85	Confident	75	Confident	47 Å²	47	80.2 Å²	80.2	22%	0.22	42%	0.421	C	S	.	.	H	α-helix	trans	-67.1	-37.5	-178.3	-67.7	-53.3	135.7	0	0	111.9	T39 K44 R45	T39-E41 VanDerWaalsContact C-N 3.33Å; T39-E41 PolarHBondContact O-N 3.39Å; E41-K44 PolarHBondContact O-N 2.85Å; E41-K44 IonicContact OE1-NZ 2.84Å; E41-K44 PolarHBondContact OE1-NZ 3.34Å; E41-K44 IonicContact OE2-NZ 2.74Å; E41-K44 PolarHBondContact OE2-NZ 3.25Å; E41-R45 VanDerWaalsContact O-CG 3.28Å; E41-R45 WeakPolarHBondContact O-CG 3.44Å; E41-R45 PolarHBondContact O-N 3.23Å
42	N	89.9	Confident	77.9	Confident	98 Å²	98	76.8 Å²	76.8	52%	0.524	40%	0.395	S	S	.	.	H	α-helix	trans	-63.7	-44.5	173	-65.5	-16	0	0	0	110.7	T39 I40 K44 R45 E46	T39-N42 PolarHBondContact O-N 3.45Å; I40-N42 VanDerWaalsContact C-N 3.34Å; I40-N42 PolarHBondContact O-N 3.28Å; N42-K44 PolarHBondContact O-N 3.34Å; N42-R45 PolarHBondContact O-N 2.91Å; N42-E46 PolarHBondContact O-N 3.08Å; N42-E46 VanDerWaalsContact O-N 3.16Å
43	F	92.3	Very high	81.1	Confident	44 Å²	44	74 Å²	74	19%	0.193	38%	0.38	C	S	.	.	H	α-helix	trans	-60.5	-43.2	176.4	178.6	-104.9	0	0	0	112.3	T39 I40 R45 E46 F47 K292 V295 I296	T39-F43 PolarHBondContact O-N 2.88Å; I40-F43 HydrophobicContact CD1-CB 4.49Å; I40-F43 HydrophobicContact CD1-CD1 4.04Å; I40-F43 PolarHBondContact O-N 3.39Å; F43-R45 PolarHBondContact O-N 3.42Å; F43-E46 PolarHBondContact O-N 3.38Å; F43-F47 HydrophobicContact CD1-CB 4.43Å; F43-F47 HydrophobicContact CD2-CB 4.37Å; F43-F47 HydrophobicContact CE1-CB 4.06Å; F43-F47 HydrophobicContact CE1-CD1 4.09Å; F43-F47 AromaticContact CE1-CG 3.99Å; F43-F47 HydrophobicContact CE1-CG 3.99Å; F43-F47 HydrophobicContact CE2-CB 3.98Å; F43-F47 HydrophobicContact CE2-CD2 4.22Å; F43-F47 HydrophobicContact CE2-CG 4.19Å; F43-F47 HydrophobicContact CZ-CB 3.82Å; F43-F47 HydrophobicContact CZ-CD1 4.12Å; F43-F47 AromaticContact CZ-CD2 3.78Å; F43-F47 HydrophobicContact CZ-CD2 3.78Å; F43-F47 HydrophobicContact CZ-CE2 4.35Å; F43-F47 AromaticContact CZ-CG 3.64Å; F43-F47 HydrophobicContact CZ-CG 3.64Å; F43-F47 WeakPolarHBondContact O-CB 3.41Å; F43-F47 PolarHBondContact O-N 3.3Å; F43-K292 HydrophobicContact CD1-CD 4.34Å; F43-K292 HydrophobicContact CD1-CG 3.82Å; F43-K292 HydrophobicContact CE1-CD 4.3Å; F43-K292 HydrophobicContact CE1-CG 3.6Å; F43-K292 HydrophobicContact CG-CD 4.45Å; F43-K292 HydrophobicContact CG-CG 4.41Å; F43-K292 HydrophobicContact CZ-CD 4.39Å; F43-K292 VanDerWaalsContact CZ-CE 3.5Å; F43-K292 HydrophobicContact CZ-CG 4.05Å; F43-V295 HydrophobicContact CD1-CG1 4.06Å; F43-V295 HydrophobicContact CE1-CB 4.32Å; F43-V295 HydrophobicContact CE1-CG1 3.66Å; F43-I296 HydrophobicContact CE1-CG1 4.3Å; F43-I296 HydrophobicContact CZ-CD1 4.4Å; F43-I296 HydrophobicContact CZ-CG1 4.2Å
44	K	92.6	Very high	84	Confident	13 Å²	13	71.7 Å²	71.7	6%	0.057	37%	0.366	C	S	.	.	H	α-helix	trans	-60.1	-45.6	177.1	-72.5	166.9	63.8	-154	0	111.5	I40 E41 N42 E46 F48 Y105 E196 V295	I40-K44 HydrophobicContact CD1-CG 4.48Å; I40-K44 HydrophobicContact CG1-CD 4.09Å; I40-K44 HydrophobicContact CG1-CG 4.29Å; I40-K44 WeakPolarHBondContact O-CG 3.48Å; I40-K44 PolarHBondContact O-N 2.99Å; E41-K44 PolarHBondContact O-N 2.85Å; E41-K44 IonicContact OE1-NZ 2.84Å; E41-K44 PolarHBondContact OE1-NZ 3.34Å; E41-K44 IonicContact OE2-NZ 2.74Å; E41-K44 PolarHBondContact OE2-NZ 3.25Å; N42-K44 PolarHBondContact O-N 3.34Å; K44-E46 VanDerWaalsContact C-N 3.31Å; K44-E46 PolarHBondContact O-N 3.11Å; K44-F48 HydrophobicContact CB-CD2 3.76Å; K44-F48 HydrophobicContact CB-CE2 3.87Å; K44-F48 HydrophobicContact CD-CE2 4.37Å; K44-F48 HydrophobicContact CG-CD2 4.1Å; K44-F48 HydrophobicContact CG-CE2 3.67Å; K44-F48 WeakPolarHBondContact O-CB 3.2Å; K44-F48 WeakPolarHBondContact O-CD2 3.42Å; K44-F48 PolarHBondContact O-N 3.06Å; K44-Y105 HydrophobicContact CB-CD1 4.33Å; K44-Y105 HydrophobicContact CB-CE1 4Å; K44-E196 IonicContact NZ-OE1 3.88Å; K44-V295 HydrophobicContact CD-CG2 4.25Å; K44-V295 HydrophobicContact CG-CG1 4.42Å; K44-V295 HydrophobicContact CG-CG2 3.8Å
45	R	93.6	Very high	86.9	Confident	96 Å²	96	66 Å²	66	36%	0.362	34%	0.336	S	S	.	.	H	α-helix	trans	-62.9	-33.5	-178.9	-72.5	171.1	179	175.6	-0.8	113.3	E41 N42 F43 P49 Y105 G108 S109	E41-R45 VanDerWaalsContact O-CG 3.28Å; E41-R45 WeakPolarHBondContact O-CG 3.44Å; E41-R45 PolarHBondContact O-N 3.23Å; N42-R45 PolarHBondContact O-N 2.91Å; F43-R45 PolarHBondContact O-N 3.42Å; R45-P49 WeakPolarHBondContact O-CD 3.47Å; R45-P49 VanDerWaalsContact O-CG 3.23Å; R45-P49 WeakPolarHBondContact O-CG 3.4Å; R45-Y105 HydrophobicContact CG-CD1 4.43Å; R45-G108 VanDerWaalsContact CZ-O 3.22Å; R45-G108 PolarHBondContact NE-O 3.19Å; R45-G108 PolarHBondContact NH2-O 2.92Å; R45-S109 PolarHBondContact NE-OG 3.24Å; R45-S109 VanDerWaalsContact NE-OG 3.12Å
46	E	94.3	Very high	89.3	Confident	146 Å²	146	64.5 Å²	64.5	68%	0.682	32%	0.318	S	S	*	.	H	α-helix	trans	-85.6	-43.6	176.5	-67.7	175.3	-169.9	0	0	112.6	N42 F43 K44	N42-E46 PolarHBondContact O-N 3.08Å; N42-E46 VanDerWaalsContact O-N 3.16Å; F43-E46 PolarHBondContact O-N 3.38Å; K44-E46 VanDerWaalsContact C-N 3.31Å; K44-E46 PolarHBondContact O-N 3.11Å
47	F	96.6	Very high	91.5	Very high	51 Å²	51	58.7 Å²	58.7	22%	0.224	30%	0.304	C	S	.	.	H	α-helix	trans	-76.1	-46.6	-171	178.5	-104.9	0	0	0	113.2	F43 V51 V295 I296 A299	F43-F47 HydrophobicContact CD1-CB 4.43Å; F43-F47 HydrophobicContact CD2-CB 4.37Å; F43-F47 HydrophobicContact CE1-CB 4.06Å; F43-F47 HydrophobicContact CE1-CD1 4.09Å; F43-F47 AromaticContact CE1-CG 3.99Å; F43-F47 HydrophobicContact CE1-CG 3.99Å; F43-F47 HydrophobicContact CE2-CB 3.98Å; F43-F47 HydrophobicContact CE2-CD2 4.22Å; F43-F47 HydrophobicContact CE2-CG 4.19Å; F43-F47 HydrophobicContact CZ-CB 3.82Å; F43-F47 HydrophobicContact CZ-CD1 4.12Å; F43-F47 AromaticContact CZ-CD2 3.78Å; F43-F47 HydrophobicContact CZ-CD2 3.78Å; F43-F47 HydrophobicContact CZ-CE2 4.35Å; F43-F47 AromaticContact CZ-CG 3.64Å; F43-F47 HydrophobicContact CZ-CG 3.64Å; F43-F47 WeakPolarHBondContact O-CB 3.41Å; F43-F47 PolarHBondContact O-N 3.3Å; F47-V51 HydrophobicContact CD2-CG2 4.08Å; F47-V51 HydrophobicContact CE1-CG2 4.17Å; F47-V51 HydrophobicContact CE2-CG2 3.68Å; F47-V51 HydrophobicContact CG-CG2 4.48Å; F47-V51 HydrophobicContact CZ-CG2 3.74Å; F47-V51 WeakPolarHBondContact O-CG2 3.38Å; F47-V51 PolarHBondContact O-N 3.46Å; F47-V295 HydrophobicContact CD1-CG1 3.69Å; F47-V295 HydrophobicContact CE1-CG1 4.03Å; F47-I296 HydrophobicContact CE1-CG1 4.33Å; F47-I296 HydrophobicContact CZ-CG1 4.09Å; F47-A299 HydrophobicContact CE1-CB 3.69Å; F47-A299 HydrophobicContact CZ-CB 4.13Å
48	F	96.4	Very high	93.3	Very high	3 Å²	3	60 Å²	60	1%	0.013	30%	0.298	C	S	.	.	H	α-helix	trans	-65	-45.4	-172.7	-78.7	-52.3	0	0	0	113.9	K44 V50 V51 Y52 Y105 V295 L298	K44-F48 HydrophobicContact CB-CD2 3.76Å; K44-F48 HydrophobicContact CB-CE2 3.87Å; K44-F48 HydrophobicContact CD-CE2 4.37Å; K44-F48 HydrophobicContact CG-CD2 4.1Å; K44-F48 HydrophobicContact CG-CE2 3.67Å; K44-F48 WeakPolarHBondContact O-CB 3.2Å; K44-F48 WeakPolarHBondContact O-CD2 3.42Å; K44-F48 PolarHBondContact O-N 3.06Å; F48-V50 VanDerWaalsContact C-N 3.32Å; F48-V50 PolarHBondContact O-N 3.21Å; F48-V51 PolarHBondContact O-N 2.85Å; F48-Y52 HydrophobicContact CB-CD2 4Å; F48-Y52 HydrophobicContact CB-CE2 3.77Å; F48-Y52 AromaticContact CD1-CE1 3.95Å; F48-Y52 HydrophobicContact CD1-CE1 3.95Å; F48-Y52 AromaticContact CD1-CE2 3.81Å; F48-Y52 HydrophobicContact CD1-CE2 3.81Å; F48-Y52 AromaticContact CD1-CZ 3.46Å; F48-Y52 VanDerWaalsContact CD1-CZ 3.46Å; F48-Y52 WeakPolarHBondContact CD1-OH 3.46Å; F48-Y52 HydrophobicContact CE1-CE1 4.43Å; F48-Y52 AromaticContact CE1-CZ 3.92Å; F48-Y52 WeakPolarHBondContact CE1-OH 3.28Å; F48-Y52 AromaticContact CG-CE2 3.94Å; F48-Y52 HydrophobicContact CG-CE2 3.94Å; F48-Y52 VanDerWaalsContact O-CB 3.23Å; F48-Y52 WeakPolarHBondContact O-CB 3.04Å; F48-Y52 WeakPolarHBondContact O-CD2 3.49Å; F48-Y52 VanDerWaalsContact O-CG 3.22Å; F48-Y52 PolarHBondContact O-N 3.18Å; F48-Y105 HydrophobicContact CB-CD2 3.49Å; F48-Y105 VanDerWaalsContact CB-CD2 3.49Å; F48-Y105 HydrophobicContact CB-CE2 3.76Å; F48-Y105 HydrophobicContact CB-CG 4.05Å; F48-Y105 HydrophobicContact CD2-CD1 4.18Å; F48-Y105 AromaticContact CD2-CD2 3.84Å; F48-Y105 HydrophobicContact CD2-CD2 3.84Å; F48-Y105 AromaticContact CD2-CE1 3.72Å; F48-Y105 HydrophobicContact CD2-CE1 3.72Å; F48-Y105 AromaticContact CD2-CE2 3.34Å; F48-Y105 HydrophobicContact CD2-CE2 3.34Å; F48-Y105 HydrophobicContact CD2-CG 4.25Å; F48-Y105 AromaticContact CD2-CZ 3.26Å; F48-Y105 HydrophobicContact CE2-CE1 4.17Å; F48-Y105 HydrophobicContact CE2-CE2 4Å; F48-Y105 AromaticContact CE2-CZ 3.6Å; F48-Y105 WeakPolarHBondContact CE2-OH 3.44Å; F48-Y105 HydrophobicContact CG-CD2 4.01Å; F48-Y105 AromaticContact CG-CE2 3.74Å; F48-Y105 HydrophobicContact CG-CE2 3.74Å; F48-V295 HydrophobicContact CE1-CG1 3.83Å; F48-V295 HydrophobicContact CE2-CG1 3.94Å; F48-V295 HydrophobicContact CE2-CG2 4.26Å; F48-V295 HydrophobicContact CZ-CB 4.12Å; F48-V295 HydrophobicContact CZ-CG1 3.53Å; F48-V295 HydrophobicContact CZ-CG2 4.01Å; F48-L298 HydrophobicContact CE1-CD2 4.45Å; F48-L298 HydrophobicContact CZ-CD2 4.24Å
49	P	97.8	Very high	94.6	Very high	5 Å²	5	57.6 Å²	57.6	3%	0.032	28%	0.282	C	S	.	.	H	α-helix	trans	-56.6	-46.4	179.1	-27.5	36.5	0	0	0	112.6	R45 V51 L53 A102 L106	R45-P49 WeakPolarHBondContact O-CD 3.47Å; R45-P49 VanDerWaalsContact O-CG 3.23Å; R45-P49 WeakPolarHBondContact O-CG 3.4Å; P49-V51 PolarHBondContact O-N 3.38Å; P49-L53 WeakPolarHBondContact O-CB 3.25Å; P49-L53 WeakPolarHBondContact O-CG 3.22Å; P49-L53 PolarHBondContact O-N 2.73Å; P49-A102 HydrophobicContact CB-CB 4.25Å; P49-L106 HydrophobicContact CB-CD1 4.25Å; P49-L106 HydrophobicContact CB-CD2 3.81Å; P49-L106 HydrophobicContact CB-CG 3.8Å; P49-L106 HydrophobicContact CG-CD2 3.84Å; P49-L106 HydrophobicContact CG-CG 3.79Å
50	V	98.1	Very high	95.4	Very high	87 Å²	87	56 Å²	56	53%	0.527	27%	0.272	S	S	.	.	H	α-helix	trans	-59.6	-52.3	-179.8	177.8	0	0	0	0	110.4	F48 L53 I54	F48-V50 VanDerWaalsContact C-N 3.32Å; F48-V50 PolarHBondContact O-N 3.21Å; V50-L53 PolarHBondContact O-N 3.35Å; V50-I54 HydrophobicContact CG1-CD1 3.93Å; V50-I54 VanDerWaalsContact O-CG1 3.25Å; V50-I54 WeakPolarHBondContact O-CG1 3.5Å; V50-I54 PolarHBondContact O-N 3.01Å; V50-I54 VanDerWaalsContact O-N 3.1Å
51	V	98.1	Very high	96	Very high	31 Å²	31	60.9 Å²	60.9	19%	0.188	30%	0.298	C	S	.	.	H	α-helix	trans	-69.5	-40.7	-176	180	0	0	0	0	111.8	F47 F48 P49 L53 I54 I55 A299	F47-V51 HydrophobicContact CD2-CG2 4.08Å; F47-V51 HydrophobicContact CE1-CG2 4.17Å; F47-V51 HydrophobicContact CE2-CG2 3.68Å; F47-V51 HydrophobicContact CG-CG2 4.48Å; F47-V51 HydrophobicContact CZ-CG2 3.74Å; F47-V51 WeakPolarHBondContact O-CG2 3.38Å; F47-V51 PolarHBondContact O-N 3.46Å; F48-V51 PolarHBondContact O-N 2.85Å; P49-V51 PolarHBondContact O-N 3.38Å; V51-L53 PolarHBondContact O-N 3.34Å; V51-I54 PolarHBondContact O-N 2.89Å; V51-I55 HydrophobicContact CG1-CD1 3.69Å; V51-I55 HydrophobicContact CG1-CG1 4.28Å; V51-I55 VanDerWaalsContact O-CG1 3.23Å; V51-I55 WeakPolarHBondContact O-CG1 3.39Å; V51-I55 PolarHBondContact O-N 3Å; V51-A299 HydrophobicContact CG1-CB 3.89Å
52	Y	98	Very high	96.5	Very high	10 Å²	10	59.5 Å²	59.5	4%	0.039	30%	0.296	C	S	.	.	H	α-helix	trans	-65.3	-38.1	178.1	-70.7	-20.3	0	0	0	112.9	F48 I55 F56 L98 R101 Y105 A302	F48-Y52 HydrophobicContact CB-CD2 4Å; F48-Y52 HydrophobicContact CB-CE2 3.77Å; F48-Y52 AromaticContact CD1-CE1 3.95Å; F48-Y52 HydrophobicContact CD1-CE1 3.95Å; F48-Y52 AromaticContact CD1-CE2 3.81Å; F48-Y52 HydrophobicContact CD1-CE2 3.81Å; F48-Y52 AromaticContact CD1-CZ 3.46Å; F48-Y52 VanDerWaalsContact CD1-CZ 3.46Å; F48-Y52 WeakPolarHBondContact CD1-OH 3.46Å; F48-Y52 HydrophobicContact CE1-CE1 4.43Å; F48-Y52 AromaticContact CE1-CZ 3.92Å; F48-Y52 WeakPolarHBondContact CE1-OH 3.28Å; F48-Y52 AromaticContact CG-CE2 3.94Å; F48-Y52 HydrophobicContact CG-CE2 3.94Å; F48-Y52 VanDerWaalsContact O-CB 3.23Å; F48-Y52 WeakPolarHBondContact O-CB 3.04Å; F48-Y52 WeakPolarHBondContact O-CD2 3.49Å; F48-Y52 VanDerWaalsContact O-CG 3.22Å; F48-Y52 PolarHBondContact O-N 3.18Å; Y52-I55 PolarHBondContact O-N 3.17Å; Y52-F56 VanDerWaalsContact O-CB 3.27Å; Y52-F56 WeakPolarHBondContact O-CB 3.26Å; Y52-F56 PolarHBondContact O-N 3.3Å; Y52-L98 HydrophobicContact CD1-CD2 3.83Å; Y52-L98 HydrophobicContact CE1-CD2 4.27Å; Y52-L98 HydrophobicContact CG-CD2 4.06Å; Y52-R101 HydrophobicContact CD2-CB 3.7Å; Y52-R101 HydrophobicContact CE2-CB 3.63Å; Y52-R101 HydrophobicContact CE2-CG 4.48Å; Y52-Y105 HydrophobicContact CE2-CD2 4.33Å; Y52-Y105 HydrophobicContact CE2-CE2 4.06Å; Y52-A302 HydrophobicContact CE1-CB 4.49Å
53	L	98.3	Very high	96.9	Very high	78 Å²	78	54.9 Å²	54.9	41%	0.408	27%	0.271	S	S	.	.	H	α-helix	trans	-69.5	-37.9	175.8	-69.4	175	0	0	0	112	P49 V50 V51 F56 V57 A102	P49-L53 WeakPolarHBondContact O-CB 3.25Å; P49-L53 WeakPolarHBondContact O-CG 3.22Å; P49-L53 PolarHBondContact O-N 2.73Å; V50-L53 PolarHBondContact O-N 3.35Å; V51-L53 PolarHBondContact O-N 3.34Å; L53-F56 WeakPolarHBondContact O-CB 3.03Å; L53-F56 PolarHBondContact O-N 3.19Å; L53-V57 WeakPolarHBondContact O-CG2 3.46Å; L53-V57 PolarHBondContact O-N 3.41Å; L53-A102 HydrophobicContact CD2-CB 4.22Å; L53-A102 HydrophobicContact CG-CB 4.12Å
54	I	98.3	Very high	97.2	Very high	90 Å²	90	54.1 Å²	54.1	46%	0.462	28%	0.276	S	S	.	.	H	α-helix	trans	-60.2	-51.4	172.3	-69.5	167.7	0	0	0	110	V50 V51 F56 V57 W58	V50-I54 HydrophobicContact CG1-CD1 3.93Å; V50-I54 VanDerWaalsContact O-CG1 3.25Å; V50-I54 WeakPolarHBondContact O-CG1 3.5Å; V50-I54 PolarHBondContact O-N 3.01Å; V50-I54 VanDerWaalsContact O-N 3.1Å; V51-I54 PolarHBondContact O-N 2.89Å; I54-F56 PolarHBondContact O-N 3.46Å; I54-V57 PolarHBondContact O-N 3.39Å; I54-W58 PolarHBondContact O-N 2.94Å; I54-W58 VanDerWaalsContact O-N 3.12Å
55	I	98.4	Very high	97.4	Very high	4 Å²	4	57.6 Å²	57.6	2%	0.021	30%	0.295	C	S	.	.	H	α-helix	trans	-59.7	-38.8	177.9	-65.4	165.5	0	0	0	110.4	V51 Y52 G59 L98 A302 A303	V51-I55 HydrophobicContact CG1-CD1 3.69Å; V51-I55 HydrophobicContact CG1-CG1 4.28Å; V51-I55 VanDerWaalsContact O-CG1 3.23Å; V51-I55 WeakPolarHBondContact O-CG1 3.39Å; V51-I55 PolarHBondContact O-N 3Å; Y52-I55 PolarHBondContact O-N 3.17Å; I55-G59 VanDerWaalsContact O-CA 3.25Å; I55-G59 WeakPolarHBondContact O-CA 3.29Å; I55-G59 PolarHBondContact O-N 2.92Å; I55-L98 HydrophobicContact CB-CD1 3.84Å; I55-L98 HydrophobicContact CG2-CD1 3.42Å; I55-L98 VanDerWaalsContact CG2-CD1 3.42Å; I55-A302 HydrophobicContact CD1-CB 4.02Å; I55-A303 HydrophobicContact CD1-CB 3.87Å; I55-A303 HydrophobicContact CG1-CB 4.05Å
56	F	98.6	Very high	97.5	Very high	64 Å²	64	53.2 Å²	53.2	28%	0.281	28%	0.279	S	S	.	.	H	α-helix	trans	-60.4	-53.2	177.7	174.8	-102.6	0	0	0	112.4	Y52 L53 I54 G59 V60 I95 L98 P99	Y52-F56 VanDerWaalsContact O-CB 3.27Å; Y52-F56 WeakPolarHBondContact O-CB 3.26Å; Y52-F56 PolarHBondContact O-N 3.3Å; L53-F56 WeakPolarHBondContact O-CB 3.03Å; L53-F56 PolarHBondContact O-N 3.19Å; I54-F56 PolarHBondContact O-N 3.46Å; F56-G59 PolarHBondContact O-N 3.12Å; F56-V60 HydrophobicContact CD2-CG2 3.92Å; F56-V60 HydrophobicContact CE2-CG2 3.67Å; F56-V60 HydrophobicContact CZ-CG2 4.07Å; F56-V60 WeakPolarHBondContact O-CB 3.39Å; F56-V60 VanDerWaalsContact O-CG2 3.26Å; F56-V60 WeakPolarHBondContact O-CG2 3.48Å; F56-V60 PolarHBondContact O-N 3.32Å; F56-I95 HydrophobicContact CB-CG2 4.37Å; F56-I95 HydrophobicContact CD2-CG2 3.66Å; F56-I95 WeakPolarHBondContact CD2-O 3.31Å; F56-I95 HydrophobicContact CE2-CG2 4.41Å; F56-I95 HydrophobicContact CG-CG2 4.39Å; F56-L98 HydrophobicContact CB-CB 4.34Å; F56-L98 HydrophobicContact CB-CD1 4.43Å; F56-P99 HydrophobicContact CD1-CG 4.36Å; F56-P99 HydrophobicContact CD2-CG 3.63Å; F56-P99 HydrophobicContact CE1-CG 4.35Å; F56-P99 HydrophobicContact CE2-CG 3.62Å; F56-P99 HydrophobicContact CG-CG 4.02Å; F56-P99 HydrophobicContact CZ-CG 3.99Å
57	V	98.3	Very high	97.6	Very high	74 Å²	74	47.5 Å²	47.5	45%	0.448	25%	0.253	S	S	.	.	H	α-helix	trans	-61.4	-53.4	-177.8	172.8	0	0	0	0	111	L53 I54 G59 L61	L53-V57 WeakPolarHBondContact O-CG2 3.46Å; L53-V57 PolarHBondContact O-N 3.41Å; I54-V57 PolarHBondContact O-N 3.39Å; V57-G59 PolarHBondContact O-N 3.02Å; V57-L61 HydrophobicContact CG1-CD1 4.06Å; V57-L61 WeakPolarHBondContact O-CB 3.48Å; V57-L61 VanDerWaalsContact O-CG 3.25Å; V57-L61 WeakPolarHBondContact O-CG 3.19Å; V57-L61 PolarHBondContact O-N 3.12Å; V57-L61 VanDerWaalsContact O-N 3.16Å
58	W	97.6	Very high	97.6	Very high	172 Å²	172	51 Å²	51	65%	0.652	27%	0.266	S	S	*	.	H	α-helix	trans	-68.8	-37.1	-177.6	-69.3	108.2	0	0	0	112.5	I54 G62	I54-W58 PolarHBondContact O-N 2.94Å; I54-W58 VanDerWaalsContact O-N 3.12Å; W58-G62 PolarHBondContact O-N 3.11Å
59	G	97.8	Very high	97.5	Very high	0 Å²	0	50.8 Å²	50.8	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-66.1	-45.4	178.8	0	0	0	0	0	112.8	I55 F56 V57 N63 I95	I55-G59 VanDerWaalsContact O-CA 3.25Å; I55-G59 WeakPolarHBondContact O-CA 3.29Å; I55-G59 PolarHBondContact O-N 2.92Å; F56-G59 PolarHBondContact O-N 3.12Å; V57-G59 PolarHBondContact O-N 3.02Å; G59-N63 VanDerWaalsContact O-CB 3.28Å; G59-N63 WeakPolarHBondContact O-CB 3.49Å; G59-N63 PolarHBondContact O-N 3.49Å; G59-N63 PolarHBondContact O-ND2 3.16Å; G59-I95 VanDerWaalsContact CA-CD1 3.44Å
60	V	98.1	Very high	97.3	Very high	57 Å²	57	51.1 Å²	51.1	35%	0.345	27%	0.266	S	S	.	.	H	α-helix	trans	-64.2	-46.7	176.5	169.5	0	0	0	0	110.7	F56 G64 I95	F56-V60 HydrophobicContact CD2-CG2 3.92Å; F56-V60 HydrophobicContact CE2-CG2 3.67Å; F56-V60 HydrophobicContact CZ-CG2 4.07Å; F56-V60 WeakPolarHBondContact O-CB 3.39Å; F56-V60 VanDerWaalsContact O-CG2 3.26Å; F56-V60 WeakPolarHBondContact O-CG2 3.48Å; F56-V60 PolarHBondContact O-N 3.32Å; V60-G64 VanDerWaalsContact O-CA 3.26Å; V60-G64 WeakPolarHBondContact O-CA 3.48Å; V60-G64 PolarHBondContact O-N 2.91Å; V60-I95 HydrophobicContact CG2-CG2 3.72Å
61	L	97.3	Very high	97	Very high	109 Å²	109	52.6 Å²	52.6	57%	0.571	27%	0.27	S	S	*	.	H	α-helix	trans	-62	-50.3	179.5	-69.2	173.5	0	0	0	111.5	V57 L65	V57-L61 HydrophobicContact CG1-CD1 4.06Å; V57-L61 WeakPolarHBondContact O-CB 3.48Å; V57-L61 VanDerWaalsContact O-CG 3.25Å; V57-L61 WeakPolarHBondContact O-CG 3.19Å; V57-L61 PolarHBondContact O-N 3.12Å; V57-L61 VanDerWaalsContact O-N 3.16Å; L61-L65 VanDerWaalsContact O-CB 3.22Å; L61-L65 WeakPolarHBondContact O-CB 3.49Å; L61-L65 PolarHBondContact O-N 3.49Å; L61-L65 VanDerWaalsContact O-N 3.11Å
62	G	97.1	Very high	96.6	Very high	18 Å²	18	52.6 Å²	52.6	19%	0.186	27%	0.268	C	S	.	.	H	α-helix	trans	-67.2	-52.8	-177	0	0	0	0	0	112.9	W58 S66	W58-G62 PolarHBondContact O-N 3.11Å; G62-S66 WeakPolarHBondContact O-CB 3.47Å; G62-S66 PolarHBondContact O-N 3.06Å; G62-S66 PolarHBondContact O-OG 2.66Å
63	N	98	Very high	95.9	Very high	0 Å²	0	56.8 Å²	56.8	0%	0	30%	0.297	C	S	.	.	H	α-helix	trans	-75.1	-34.4	-177.4	-66.1	-67	0	0	0	112.1	G59 S66 V67 L92 T305	G59-N63 VanDerWaalsContact O-CB 3.28Å; G59-N63 WeakPolarHBondContact O-CB 3.49Å; G59-N63 PolarHBondContact O-N 3.49Å; G59-N63 PolarHBondContact O-ND2 3.16Å; N63-S66 PolarHBondContact O-N 3.49Å; N63-V67 WeakPolarHBondContact O-CG2 3.47Å; N63-V67 PolarHBondContact O-N 2.96Å; N63-L92 HydrophobicContact CB-CD1 4.36Å; N63-L92 HydrophobicContact CB-CD2 3.8Å; N63-L92 HydrophobicContact CB-CG 3.71Å; N63-T305 PolarHBondContact ND2-O 2.98Å
64	G	97.7	Very high	95.2	Very high	28 Å²	28	56.8 Å²	56.8	29%	0.289	29%	0.292	S	S	.	.	H	α-helix	trans	-61.4	-48.4	174.6	0	0	0	0	0	111.9	V60 S66 V67 Y68	V60-G64 VanDerWaalsContact O-CA 3.26Å; V60-G64 WeakPolarHBondContact O-CA 3.48Å; V60-G64 PolarHBondContact O-N 2.91Å; G64-S66 VanDerWaalsContact C-N 3.27Å; G64-S66 PolarHBondContact O-N 3.02Å; G64-V67 PolarHBondContact O-N 3.37Å; G64-Y68 WeakPolarHBondContact O-CB 3.18Å; G64-Y68 PolarHBondContact O-N 3.17Å
65	L	96.5	Very high	94.1	Very high	87 Å²	87	62.4 Å²	62.4	46%	0.455	31%	0.313	S	S	.	.	H	α-helix	trans	-59.3	-41.2	172.8	177.6	61.2	0	0	0	111.4	L61 Y68 V69 L323	L61-L65 VanDerWaalsContact O-CB 3.22Å; L61-L65 WeakPolarHBondContact O-CB 3.49Å; L61-L65 PolarHBondContact O-N 3.49Å; L61-L65 VanDerWaalsContact O-N 3.11Å; L65-Y68 HydrophobicContact CD1-CD1 4.48Å; L65-Y68 WeakPolarHBondContact O-CB 3.28Å; L65-Y68 PolarHBondContact O-N 3.03Å; L65-V69 HydrophobicContact CD1-CG2 4.13Å; L65-V69 HydrophobicContact CG-CG2 4.42Å; L65-V69 VanDerWaalsContact O-CG2 3.28Å; L65-V69 WeakPolarHBondContact O-CG2 3.29Å; L65-V69 PolarHBondContact O-N 3.44Å; L65-L323 HydrophobicContact CD1-CD1 4.4Å
66	S	96.4	Very high	93.1	Very high	4 Å²	4	69.8 Å²	69.8	3%	0.028	35%	0.345	C	S	.	.	H	α-helix	trans	-66	-45.4	-177.8	-59.6	0	0	0	0	112.3	G62 N63 G64 Y68 V69 F70 Y312	G62-S66 WeakPolarHBondContact O-CB 3.47Å; G62-S66 PolarHBondContact O-N 3.06Å; G62-S66 PolarHBondContact O-OG 2.66Å; N63-S66 PolarHBondContact O-N 3.49Å; G64-S66 VanDerWaalsContact C-N 3.27Å; G64-S66 PolarHBondContact O-N 3.02Å; S66-Y68 VanDerWaalsContact C-N 3.35Å; S66-V69 PolarHBondContact O-N 3.22Å; S66-F70 WeakPolarHBondContact O-CB 3.41Å; S66-F70 WeakPolarHBondContact O-CD2 3.36Å; S66-F70 WeakPolarHBondContact O-CG 3.49Å; S66-F70 PolarHBondContact O-N 3.29Å; S66-Y312 VanDerWaalsContact CB-CD2 3.48Å; S66-Y312 VanDerWaalsContact OG-CD2 3.32Å; S66-Y312 WeakPolarHBondContact OG-CD2 3.19Å
67	V	97.1	Very high	92.4	Very high	25 Å²	25	69.8 Å²	69.8	15%	0.152	35%	0.353	C	S	.	.	H	α-helix	trans	-59	-47.8	172.9	170.4	0	0	0	0	110.2	N63 G64 V69 F70 L71 L85 A88 I89 L92	N63-V67 WeakPolarHBondContact O-CG2 3.47Å; N63-V67 PolarHBondContact O-N 2.96Å; G64-V67 PolarHBondContact O-N 3.37Å; V67-V69 VanDerWaalsContact C-N 3.33Å; V67-V69 PolarHBondContact O-N 3.38Å; V67-F70 PolarHBondContact O-N 3.05Å; V67-L71 HydrophobicContact CG1-CD1 3.76Å; V67-L71 HydrophobicContact CG1-CG 4.26Å; V67-L71 VanDerWaalsContact O-CG 3.29Å; V67-L71 WeakPolarHBondContact O-CG 3.27Å; V67-L71 PolarHBondContact O-N 3.47Å; V67-L85 HydrophobicContact CB-CD1 4.46Å; V67-L85 HydrophobicContact CG1-CD1 4.18Å; V67-L85 HydrophobicContact CG2-CD1 4.21Å; V67-A88 HydrophobicContact CG2-CB 3.7Å; V67-I89 HydrophobicContact CG2-CG1 4.29Å; V67-L92 HydrophobicContact CB-CD1 4.38Å; V67-L92 HydrophobicContact CG2-CD1 3.73Å
68	Y	95.4	Very high	91.9	Very high	124 Å²	124	68.1 Å²	68.1	49%	0.486	34%	0.343	S	S	.	.	H	α-helix	trans	-54.7	-47.4	176.6	172.7	-98.9	0	0	0	112.1	G64 L65 S66 L71 Q72 A326	G64-Y68 WeakPolarHBondContact O-CB 3.18Å; G64-Y68 PolarHBondContact O-N 3.17Å; L65-Y68 HydrophobicContact CD1-CD1 4.48Å; L65-Y68 WeakPolarHBondContact O-CB 3.28Å; L65-Y68 PolarHBondContact O-N 3.03Å; S66-Y68 VanDerWaalsContact C-N 3.35Å; Y68-L71 PolarHBondContact O-N 2.87Å; Y68-Q72 WeakPolarHBondContact O-CG 3.46Å; Y68-Q72 PolarHBondContact O-N 2.86Å; Y68-Q72 PolarHBondContact OH-NE2 2.96Å; Y68-A326 HydrophobicContact CE1-CB 4.01Å
69	V	94.4	Very high	91.5	Very high	0 Å²	0	60.3 Å²	60.3	0%	0	31%	0.314	C	S	.	.	H	α-helix	trans	-65.5	-41	178.5	171.9	0	0	0	0	112	L65 S66 V67 L71 Q72 F319 R322 L323	L65-V69 HydrophobicContact CD1-CG2 4.13Å; L65-V69 HydrophobicContact CG-CG2 4.42Å; L65-V69 VanDerWaalsContact O-CG2 3.28Å; L65-V69 WeakPolarHBondContact O-CG2 3.29Å; L65-V69 PolarHBondContact O-N 3.44Å; S66-V69 PolarHBondContact O-N 3.22Å; V67-V69 VanDerWaalsContact C-N 3.33Å; V67-V69 PolarHBondContact O-N 3.38Å; V69-L71 VanDerWaalsContact C-N 3.3Å; V69-L71 PolarHBondContact O-N 2.85Å; V69-Q72 WeakPolarHBondContact O-CB 3.32Å; V69-Q72 PolarHBondContact O-N 3.21Å; V69-F319 HydrophobicContact CB-CD2 4.37Å; V69-F319 HydrophobicContact CB-CE2 3.79Å; V69-F319 HydrophobicContact CB-CZ 4.05Å; V69-F319 HydrophobicContact CG1-CD1 4.47Å; V69-F319 HydrophobicContact CG1-CD2 3.67Å; V69-F319 HydrophobicContact CG1-CE1 4.38Å; V69-F319 HydrophobicContact CG1-CE2 3.58Å; V69-F319 HydrophobicContact CG1-CG 4.15Å; V69-F319 HydrophobicContact CG1-CZ 3.96Å; V69-F319 HydrophobicContact CG2-CE2 4.45Å; V69-F319 HydrophobicContact CG2-CZ 4.21Å; V69-R322 HydrophobicContact CG1-CB 3.75Å; V69-L323 HydrophobicContact CG1-CB 4.32Å; V69-L323 HydrophobicContact CG2-CB 4.23Å; V69-L323 HydrophobicContact CG2-CD1 3.79Å
70	F	93	Very high	91.1	Very high	11 Å²	11	60.5 Å²	60.5	5%	0.048	32%	0.316	C	S	.	.	H	α-helix	trans	-67.2	-31.5	179.3	-74.6	-50.4	0	0	0	112.9	S66 V67 Q72 N81 M84 L85 Y312 F319 R322	S66-F70 WeakPolarHBondContact O-CB 3.41Å; S66-F70 WeakPolarHBondContact O-CD2 3.36Å; S66-F70 WeakPolarHBondContact O-CG 3.49Å; S66-F70 PolarHBondContact O-N 3.29Å; V67-F70 PolarHBondContact O-N 3.05Å; F70-Q72 VanDerWaalsContact C-N 3.29Å; F70-N81 HydrophobicContact CD1-CB 4.48Å; F70-M84 HydrophobicContact CE1-CB 4.14Å; F70-M84 HydrophobicContact CE1-SD 4.31Å; F70-M84 HydrophobicContact CE2-CB 3.75Å; F70-M84 HydrophobicContact CZ-CB 3.45Å; F70-M84 VanDerWaalsContact CZ-CB 3.45Å; F70-M84 HydrophobicContact CZ-CG 4.26Å; F70-M84 HydrophobicContact CZ-SD 3.89Å; F70-L85 HydrophobicContact CB-CB 4.41Å; F70-L85 HydrophobicContact CB-CD1 4Å; F70-L85 HydrophobicContact CD2-CB 4.45Å; F70-Y312 HydrophobicContact CE2-CD1 4.26Å; F70-Y312 HydrophobicContact CE2-CD2 4.1Å; F70-Y312 AromaticContact CE2-CG 3.94Å; F70-Y312 HydrophobicContact CE2-CG 3.94Å; F70-Y312 HydrophobicContact CZ-CD1 4.19Å; F70-Y312 AromaticContact CZ-CG 3.97Å; F70-Y312 HydrophobicContact CZ-CG 3.97Å; F70-F319 HydrophobicContact CD1-CD2 4.22Å; F70-F319 AromaticContact CE1-CD2 3.63Å; F70-F319 HydrophobicContact CE1-CD2 3.63Å; F70-F319 HydrophobicContact CE1-CE2 4.24Å; F70-F319 HydrophobicContact CE2-CD2 4.36Å; F70-F319 HydrophobicContact CE2-CE2 4.19Å; F70-F319 AromaticContact CZ-CD2 3.69Å; F70-F319 HydrophobicContact CZ-CD2 3.69Å; F70-F319 AromaticContact CZ-CE2 3.97Å; F70-F319 HydrophobicContact CZ-CE2 3.97Å; F70-R322 PolarHBondContact O-NH1 2.77Å
71	L	92.2	Very high	90.9	Very high	118 Å²	118	58.2 Å²	58.2	62%	0.618	30%	0.301	S	S	*	.	H	α-helix	trans	-77.9	-11	176.6	-66	176.9	0	0	0	113.6	V67 Y68 V69 L85	V67-L71 HydrophobicContact CG1-CD1 3.76Å; V67-L71 HydrophobicContact CG1-CG 4.26Å; V67-L71 VanDerWaalsContact O-CG 3.29Å; V67-L71 WeakPolarHBondContact O-CG 3.27Å; V67-L71 PolarHBondContact O-N 3.47Å; Y68-L71 PolarHBondContact O-N 2.87Å; V69-L71 VanDerWaalsContact C-N 3.3Å; V69-L71 PolarHBondContact O-N 2.85Å; L71-L85 HydrophobicContact CD2-CD1 4.49Å; L71-L85 HydrophobicContact CD2-CD2 4.24Å
72	Q	89.6	Confident	90.8	Very high	32 Å²	32	53.5 Å²	53.5	15%	0.15	28%	0.277	C	S	.	.	S	Bend	trans	-64.7	134.5	176.9	-67.2	-58.3	-39.1	0	0	111.8	Y68 V69 F70 Y74 A326	Y68-Q72 WeakPolarHBondContact O-CG 3.46Å; Y68-Q72 PolarHBondContact O-N 2.86Å; Y68-Q72 PolarHBondContact OH-NE2 2.96Å; V69-Q72 WeakPolarHBondContact O-CB 3.32Å; V69-Q72 PolarHBondContact O-N 3.21Å; F70-Q72 VanDerWaalsContact C-N 3.29Å; Q72-Y74 PolarHBondContact O-N 3.27Å; Q72-A326 HydrophobicContact CG-CB 4.08Å
73	P	83.4	Confident	90.7	Very high	97 Å²	97	52.9 Å²	52.9	63%	0.63	27%	0.269	S	S	*	.			trans	-56.8	129.3	174.3	-24	32.9	0	0	0	111.2
74	Y	84.1	Confident	90.6	Very high	78 Å²	78	52.9 Å²	52.9	31%	0.306	27%	0.269	S	S	.	.			trans	-144.1	146.4	177.5	-160.1	-104.4	0	0	0	110.9	Q72 K76 N318 D321 R322	Q72-Y74 PolarHBondContact O-N 3.27Å; Y74-K76 WeakPolarHBondContact CD1-O 3.45Å; Y74-K76 PolarHBondContact O-N 3.42Å; Y74-K76 VanDerWaalsContact O-N 3.08Å; Y74-N318 HydrophobicContact CD1-CB 3.92Å; Y74-N318 HydrophobicContact CE1-CB 3.44Å; Y74-N318 VanDerWaalsContact CE1-CB 3.44Å; Y74-D321 HydrophobicContact CE2-CB 3.79Å; Y74-D321 WeakPolarHBondContact OH-CB 3.23Å; Y74-D321 PolarHBondContact OH-OD2 3.09Å; Y74-R322 VanDerWaalsContact CB-NE 3.35Å; Y74-R322 HydrophobicContact CD1-CG 4.43Å; Y74-R322 HydrophobicContact CD2-CG 3.56Å; Y74-R322 HydrophobicContact CE2-CG 4.24Å; Y74-R322 HydrophobicContact CG-CG 3.68Å
75	K	75.4	Confident	90.5	Very high	208 Å²	208	52.4 Å²	52.4	90%	0.904	26%	0.26	S	S	*	.	S	Bend	trans	-58.9	-26.7	-172.3	-64.5	-175.6	178.6	-176.3	0	113.9
76	K	77.9	Confident	90.6	Very high	160 Å²	160	48.8 Å²	48.8	70%	0.696	24%	0.241	S	C	*	.			trans	-136.9	125.7	178.8	-62.7	-174.3	179.8	-177.4	0	110.5	Y74 R322	Y74-K76 WeakPolarHBondContact CD1-O 3.45Å; Y74-K76 PolarHBondContact O-N 3.42Å; Y74-K76 VanDerWaalsContact O-N 3.08Å; K76-R322 PolarHBondContact O-NH2 3.43Å
77	S	83	Confident	90.7	Very high	64 Å²	64	48.7 Å²	48.7	45%	0.448	24%	0.241	S	C	.	.			trans	-109.6	148	169.2	-75.7	0	0	0	0	109.3	I159 R322	S77-I159 WeakPolarHBondContact O-CD1 3.34Å; S77-R322 PolarHBondContact OG-NH2 3Å
78	T	87.7	Confident	90.7	Very high	39 Å²	39	47.5 Å²	47.5	24%	0.239	23%	0.233	C	C	.	.			trans	-122.1	160.4	-178.8	63.9	0	0	0	0	109.8	V80 N81 E317	T78-V80 PolarHBondContact O-N 3.08Å; T78-N81 WeakPolarHBondContact O-CB 3.43Å; T78-N81 PolarHBondContact O-N 2.85Å; T78-N81 VanDerWaalsContact O-N 3.12Å; T78-N81 PolarHBondContact OG1-N 3.02Å; T78-E317 HydrophobicContact CG2-CB 4.08Å; T78-E317 HydrophobicContact CG2-CG 4.13Å; T78-E317 WeakPolarHBondContact OG1-CB 3.43Å
79	S	89.8	Confident	90.8	Very high	7 Å²	7	44.6 Å²	44.6	5%	0.049	23%	0.226	C	C	.	.	H	α-helix	trans	-56.1	-36.2	171.9	40.8	0	0	0	0	112.5	N81 V82 F83 T157	S79-N81 VanDerWaalsContact C-N 3.29Å; S79-N81 PolarHBondContact O-N 2.93Å; S79-V82 WeakPolarHBondContact O-CB 3.28Å; S79-V82 PolarHBondContact O-N 2.67Å; S79-F83 WeakPolarHBondContact O-CD2 3.42Å; S79-F83 PolarHBondContact O-N 2.68Å; S79-T157 WeakPolarHBondContact CB-O 3.39Å; S79-T157 PolarHBondContact OG-O 2.97Å
80	V	89.9	Confident	91	Very high	5 Å²	5	44.7 Å²	44.7	3%	0.03	23%	0.226	C	C	.	.	H	α-helix	trans	-55.5	-42.6	174.4	170.3	0	0	0	0	112.2	T78 V82 F83 M84 L139 V142 E317	T78-V80 PolarHBondContact O-N 3.08Å; V80-V82 PolarHBondContact O-N 2.79Å; V80-F83 PolarHBondContact O-N 3.36Å; V80-M84 HydrophobicContact CG1-CE 3.61Å; V80-M84 HydrophobicContact CG1-CG 4.24Å; V80-M84 HydrophobicContact CG1-SD 3.79Å; V80-M84 WeakPolarHBondContact O-CG 3.32Å; V80-M84 PolarHBondContact O-N 3.42Å; V80-L139 HydrophobicContact CB-CD1 4.17Å; V80-L139 HydrophobicContact CG1-CD1 3.53Å; V80-L139 HydrophobicContact CG2-CD1 3.98Å; V80-V142 HydrophobicContact CG2-CG1 3.89Å; V80-E317 HydrophobicContact CB-CG 4.32Å; V80-E317 HydrophobicContact CG1-CG 4.44Å
81	N	92.4	Very high	91.3	Very high	8 Å²	8	44.2 Å²	44.2	4%	0.043	22%	0.224	C	C	.	.	H	α-helix	trans	-64.9	-31.1	179.2	-66.7	-13.6	0	0	0	111.9	F70 T78 S79 L85 E317 R322	F70-N81 HydrophobicContact CD1-CB 4.48Å; T78-N81 WeakPolarHBondContact O-CB 3.43Å; T78-N81 PolarHBondContact O-N 2.85Å; T78-N81 VanDerWaalsContact O-N 3.12Å; T78-N81 PolarHBondContact OG1-N 3.02Å; S79-N81 VanDerWaalsContact C-N 3.29Å; S79-N81 PolarHBondContact O-N 2.93Å; N81-L85 WeakPolarHBondContact O-CB 3.4Å; N81-L85 PolarHBondContact O-N 3.49Å; N81-E317 PolarHBondContact ND2-O 3.37Å; N81-E317 PolarHBondContact OD1-O 3.36Å; N81-R322 PolarHBondContact ND2-NH2 3.45Å
82	V	94.8	Very high	91.6	Very high	11 Å²	11	40.9 Å²	40.9	7%	0.067	21%	0.207	C	C	.	.	H	α-helix	trans	-67.4	-46.8	175.4	-179.7	0	0	0	0	110.9	S79 V80 L85 N86 I159 A162 W163	S79-V82 WeakPolarHBondContact O-CB 3.28Å; S79-V82 PolarHBondContact O-N 2.67Å; V80-V82 PolarHBondContact O-N 2.79Å; V82-L85 PolarHBondContact O-N 3.38Å; V82-N86 PolarHBondContact O-N 3.48Å; V82-N86 PolarHBondContact O-ND2 2.96Å; V82-I159 HydrophobicContact CG2-CG2 4.1Å; V82-A162 HydrophobicContact CB-CB 4.01Å; V82-A162 HydrophobicContact CG1-CB 4.16Å; V82-A162 HydrophobicContact CG2-CB 4.35Å; V82-W163 HydrophobicContact CG1-CD2 3.58Å; V82-W163 HydrophobicContact CG1-CE3 3.9Å; V82-W163 HydrophobicContact CG1-CG 3.97Å; V82-W163 HydrophobicContact CG1-CH2 4.33Å; V82-W163 HydrophobicContact CG1-CZ2 4.04Å; V82-W163 HydrophobicContact CG1-CZ3 4.26Å
83	F	95.5	Very high	92	Very high	4 Å²	4	44.2 Å²	44.2	2%	0.018	23%	0.225	C	C	.	.	H	α-helix	trans	-64.2	-43.6	177.7	-61.4	-59.5	0	0	0	112.1	S79 V80 N86 L87 F135 V138 V142 A162 L165 C166	S79-F83 WeakPolarHBondContact O-CD2 3.42Å; S79-F83 PolarHBondContact O-N 2.68Å; V80-F83 PolarHBondContact O-N 3.36Å; F83-N86 PolarHBondContact O-N 3.42Å; F83-L87 WeakPolarHBondContact O-CB 3.47Å; F83-L87 PolarHBondContact O-N 2.98Å; F83-F135 HydrophobicContact CD1-CD1 4.19Å; F83-V138 HydrophobicContact CD1-CG1 3.96Å; F83-V138 HydrophobicContact CD2-CG1 4.22Å; F83-V138 HydrophobicContact CE1-CG1 3.54Å; F83-V138 HydrophobicContact CE2-CG1 3.82Å; F83-V138 HydrophobicContact CG-CG1 4.3Å; F83-V138 HydrophobicContact CZ-CG1 3.46Å; F83-V138 VanDerWaalsContact CZ-CG1 3.46Å; F83-V142 HydrophobicContact CE2-CG2 3.97Å; F83-A162 HydrophobicContact CE1-CB 4.18Å; F83-A162 HydrophobicContact CE2-CB 3.86Å; F83-A162 HydrophobicContact CZ-CB 3.63Å; F83-L165 HydrophobicContact CE1-CB 4.22Å; F83-L165 HydrophobicContact CE1-CD2 4.06Å; F83-L165 HydrophobicContact CE1-CG 4.23Å; F83-L165 HydrophobicContact CZ-CB 4.5Å; F83-L165 HydrophobicContact CZ-CD2 4Å; F83-C166 WeakPolarHBondContact CD1-SG 3.38Å
84	M	95.4	Very high	92.7	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-65.1	-38.7	177.5	-70.1	179.6	171.9	0	0	112.4	F70 V80 L87 A88 L139 L311 Y312	F70-M84 HydrophobicContact CE1-CB 4.14Å; F70-M84 HydrophobicContact CE1-SD 4.31Å; F70-M84 HydrophobicContact CE2-CB 3.75Å; F70-M84 HydrophobicContact CZ-CB 3.45Å; F70-M84 VanDerWaalsContact CZ-CB 3.45Å; F70-M84 HydrophobicContact CZ-CG 4.26Å; F70-M84 HydrophobicContact CZ-SD 3.89Å; V80-M84 HydrophobicContact CG1-CE 3.61Å; V80-M84 HydrophobicContact CG1-CG 4.24Å; V80-M84 HydrophobicContact CG1-SD 3.79Å; V80-M84 WeakPolarHBondContact O-CG 3.32Å; V80-M84 PolarHBondContact O-N 3.42Å; M84-L87 PolarHBondContact O-N 2.94Å; M84-A88 WeakPolarHBondContact O-CB 3.21Å; M84-A88 PolarHBondContact O-N 2.99Å; M84-L139 HydrophobicContact CE-CD1 4.09Å; M84-L139 HydrophobicContact CE-CD2 3.72Å; M84-L139 HydrophobicContact CG-CD2 4.31Å; M84-L311 HydrophobicContact CE-CG 4.35Å; M84-Y312 HydrophobicContact CB-CD1 3.83Å; M84-Y312 HydrophobicContact CB-CE1 3.9Å; M84-Y312 HydrophobicContact CG-CD1 3.77Å; M84-Y312 HydrophobicContact CG-CE1 4.03Å; M84-Y312 HydrophobicContact SD-CD1 3.95Å
85	L	96.6	Very high	93.4	Very high	19 Å²	19	36 Å²	36	10%	0.099	18%	0.181	C	C	.	.	H	α-helix	trans	-63.3	-46.1	174.8	176.9	62.3	0	0	0	111.5	V67 F70 L71 N81 V82 L87 A88 I89	V67-L85 HydrophobicContact CB-CD1 4.46Å; V67-L85 HydrophobicContact CG1-CD1 4.18Å; V67-L85 HydrophobicContact CG2-CD1 4.21Å; F70-L85 HydrophobicContact CB-CB 4.41Å; F70-L85 HydrophobicContact CB-CD1 4Å; F70-L85 HydrophobicContact CD2-CB 4.45Å; L71-L85 HydrophobicContact CD2-CD1 4.49Å; L71-L85 HydrophobicContact CD2-CD2 4.24Å; N81-L85 WeakPolarHBondContact O-CB 3.4Å; N81-L85 PolarHBondContact O-N 3.49Å; V82-L85 PolarHBondContact O-N 3.38Å; L85-L87 VanDerWaalsContact C-N 3.33Å; L85-L87 PolarHBondContact O-N 3.02Å; L85-A88 PolarHBondContact O-N 3.31Å; L85-I89 HydrophobicContact CD1-CD1 4.02Å; L85-I89 HydrophobicContact CD1-CG1 4.32Å; L85-I89 HydrophobicContact CG-CD1 3.91Å; L85-I89 VanDerWaalsContact O-CG1 3.28Å; L85-I89 WeakPolarHBondContact O-CG1 3.38Å; L85-I89 PolarHBondContact O-N 3.28Å
86	N	98.1	Very high	94.5	Very high	11 Å²	11	29.1 Å²	29.1	6%	0.059	16%	0.159	C	C	.	.	H	α-helix	trans	-64.6	-37.9	177.9	-83.3	-92.9	0	0	0	112.3	V82 F83 I89 S90 F135 W170	V82-N86 PolarHBondContact O-N 3.48Å; V82-N86 PolarHBondContact O-ND2 2.96Å; F83-N86 PolarHBondContact O-N 3.42Å; N86-I89 PolarHBondContact O-N 3.22Å; N86-S90 WeakPolarHBondContact O-CB 3.47Å; N86-S90 PolarHBondContact O-N 3.06Å; N86-F135 HydrophobicContact CB-CE1 3.89Å; N86-F135 HydrophobicContact CB-CE2 3.93Å; N86-F135 HydrophobicContact CB-CZ 3.55Å; N86-W170 PolarHBondContact OD1-NE1 3.49Å
87	L	97.8	Very high	95.4	Very high	2 Å²	2	22 Å²	22	1%	0.01	13%	0.129	C	C	.	.	H	α-helix	trans	-60.6	-49.4	173.2	-176.1	57.5	0	0	0	111.1	F83 M84 L85 I89 S90 D91 S132 F135 L136 N308 Y312	F83-L87 WeakPolarHBondContact O-CB 3.47Å; F83-L87 PolarHBondContact O-N 2.98Å; M84-L87 PolarHBondContact O-N 2.94Å; L85-L87 VanDerWaalsContact C-N 3.33Å; L85-L87 PolarHBondContact O-N 3.02Å; L87-I89 VanDerWaalsContact C-N 3.31Å; L87-I89 PolarHBondContact O-N 3.34Å; L87-S90 WeakPolarHBondContact O-CB 3.19Å; L87-S90 PolarHBondContact O-N 3.33Å; L87-D91 VanDerWaalsContact O-CG 3.3Å; L87-D91 PolarHBondContact O-N 3.34Å; L87-S132 WeakPolarHBondContact CD1-OG 3.28Å; L87-F135 HydrophobicContact CB-CB 4.26Å; L87-F135 HydrophobicContact CB-CD2 4.27Å; L87-F135 HydrophobicContact CB-CG 4.48Å; L87-F135 HydrophobicContact CD1-CB 4.19Å; L87-F135 HydrophobicContact CD1-CD2 4.24Å; L87-L136 HydrophobicContact CD2-CD2 3.97Å; L87-L136 HydrophobicContact CD2-CG 4.31Å; L87-N308 HydrophobicContact CD2-CB 4.31Å; L87-Y312 HydrophobicContact CD2-CE1 4.08Å; L87-Y312 VanDerWaalsContact CG-OH 3.28Å; L87-Y312 WeakPolarHBondContact CG-OH 3.49Å
88	A	98.2	Very high	96.1	Very high	0 Å²	0	19 Å²	19	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-63.5	-35.7	179.1	0	0	0	0	0	112.6	V67 M84 L85 D91 L92 Y312	V67-A88 HydrophobicContact CG2-CB 3.7Å; M84-A88 WeakPolarHBondContact O-CB 3.21Å; M84-A88 PolarHBondContact O-N 2.99Å; L85-A88 PolarHBondContact O-N 3.31Å; A88-D91 PolarHBondContact O-N 3.44Å; A88-L92 WeakPolarHBondContact O-CG 3.25Å; A88-L92 PolarHBondContact O-N 2.97Å; A88-Y312 HydrophobicContact CB-CE2 3.91Å; A88-Y312 PolarHBondContact N-OH 3.14Å
89	I	98.4	Very high	96.6	Very high	63 Å²	63	19 Å²	19	32%	0.323	11%	0.109	S	C	.	.	H	α-helix	trans	-65.3	-47	173.5	-70.2	166.8	0	0	0	110.5	V67 L85 N86 L87 D91 L92 L93	V67-I89 HydrophobicContact CG2-CG1 4.29Å; L85-I89 HydrophobicContact CD1-CD1 4.02Å; L85-I89 HydrophobicContact CD1-CG1 4.32Å; L85-I89 HydrophobicContact CG-CD1 3.91Å; L85-I89 VanDerWaalsContact O-CG1 3.28Å; L85-I89 WeakPolarHBondContact O-CG1 3.38Å; L85-I89 PolarHBondContact O-N 3.28Å; N86-I89 PolarHBondContact O-N 3.22Å; L87-I89 VanDerWaalsContact C-N 3.31Å; L87-I89 PolarHBondContact O-N 3.34Å; I89-D91 VanDerWaalsContact C-N 3.27Å; I89-D91 PolarHBondContact O-N 3.39Å; I89-L92 PolarHBondContact O-N 3.27Å; I89-L93 HydrophobicContact CG2-CD1 4.03Å; I89-L93 HydrophobicContact CG2-CG 4.41Å; I89-L93 VanDerWaalsContact O-CG 3.3Å; I89-L93 WeakPolarHBondContact O-CG 3.37Å; I89-L93 PolarHBondContact O-N 3.06Å
90	S	98.4	Very high	96.9	Very high	2 Å²	2	22.7 Å²	22.7	1%	0.014	12%	0.124	C	C	.	.	H	α-helix	trans	-57.6	-43	176.4	-174.3	0	0	0	0	111.7	N86 L87 L93 F94 N128 S131	N86-S90 WeakPolarHBondContact O-CB 3.47Å; N86-S90 PolarHBondContact O-N 3.06Å; L87-S90 WeakPolarHBondContact O-CB 3.19Å; L87-S90 PolarHBondContact O-N 3.33Å; S90-L93 PolarHBondContact O-N 3.35Å; S90-F94 PolarHBondContact O-N 3.06Å; S90-F94 VanDerWaalsContact O-N 3.08Å; S90-N128 PolarHBondContact O-ND2 3.09Å; S90-N128 PolarHBondContact OG-ND2 2.83Å; S90-S131 PolarHBondContact OG-OG 2.89Å
91	D	98.4	Very high	97.3	Very high	0 Å²	0	22.6 Å²	22.6	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-63.6	-47	177.8	-70.4	-17.6	0	0	0	111.9	L87 A88 I89 L93 F94 I95 N128 T305 N308	L87-D91 VanDerWaalsContact O-CG 3.3Å; L87-D91 PolarHBondContact O-N 3.34Å; A88-D91 PolarHBondContact O-N 3.44Å; I89-D91 VanDerWaalsContact C-N 3.27Å; I89-D91 PolarHBondContact O-N 3.39Å; D91-L93 VanDerWaalsContact C-N 3.35Å; D91-L93 PolarHBondContact O-N 3.4Å; D91-F94 PolarHBondContact O-N 3.42Å; D91-I95 HydrophobicContact CB-CD1 4.29Å; D91-I95 VanDerWaalsContact O-CB 3.29Å; D91-I95 WeakPolarHBondContact O-CB 3.26Å; D91-I95 WeakPolarHBondContact O-CD1 3.21Å; D91-I95 WeakPolarHBondContact O-CG1 3.47Å; D91-I95 PolarHBondContact O-N 3.28Å; D91-N128 WeakPolarHBondContact CA-ND2 3.38Å; D91-N128 PolarHBondContact N-ND2 2.77Å; D91-N128 PolarHBondContact OD1-ND2 3.28Å; D91-T305 HydrophobicContact CB-CG2 3.96Å; D91-T305 VanDerWaalsContact OD1-CG2 3.3Å; D91-T305 WeakPolarHBondContact OD1-CG2 3.29Å; D91-N308 PolarHBondContact OD2-ND2 3.12Å
92	L	98.5	Very high	97.5	Very high	49 Å²	49	22.3 Å²	22.3	26%	0.257	12%	0.122	S	C	.	.	H	α-helix	trans	-61.6	-41.9	177.2	-75.9	172.7	0	0	0	112.5	N63 V67 A88 I89 F94 I95 S96	N63-L92 HydrophobicContact CB-CD1 4.36Å; N63-L92 HydrophobicContact CB-CD2 3.8Å; N63-L92 HydrophobicContact CB-CG 3.71Å; V67-L92 HydrophobicContact CB-CD1 4.38Å; V67-L92 HydrophobicContact CG2-CD1 3.73Å; A88-L92 WeakPolarHBondContact O-CG 3.25Å; A88-L92 PolarHBondContact O-N 2.97Å; I89-L92 PolarHBondContact O-N 3.27Å; L92-F94 PolarHBondContact O-N 3.4Å; L92-I95 PolarHBondContact O-N 3.02Å; L92-S96 WeakPolarHBondContact O-CB 3.35Å; L92-S96 PolarHBondContact O-N 2.69Å
93	L	98.2	Very high	97.6	Very high	101 Å²	101	23.7 Å²	23.7	53%	0.529	13%	0.129	S	C	.	.	H	α-helix	trans	-59.5	-46.8	176.7	-72	172.9	0	0	0	110.8	I89 S90 D91 S96 W170	I89-L93 HydrophobicContact CG2-CD1 4.03Å; I89-L93 HydrophobicContact CG2-CG 4.41Å; I89-L93 VanDerWaalsContact O-CG 3.3Å; I89-L93 WeakPolarHBondContact O-CG 3.37Å; I89-L93 PolarHBondContact O-N 3.06Å; S90-L93 PolarHBondContact O-N 3.35Å; D91-L93 VanDerWaalsContact C-N 3.35Å; D91-L93 PolarHBondContact O-N 3.4Å; L93-S96 PolarHBondContact O-OG 3.46Å; L93-W170 HydrophobicContact CD1-CH2 4.2Å
94	F	98.4	Very high	97.6	Very high	3 Å²	3	23.6 Å²	23.6	1%	0.013	13%	0.128	C	C	.	.	H	α-helix	trans	-67.8	-46.7	176.2	166.5	-110.2	0	0	0	112.7	S90 D91 L92 S96 T97 L98 L125 N128 A302 T305	S90-F94 PolarHBondContact O-N 3.06Å; S90-F94 VanDerWaalsContact O-N 3.08Å; D91-F94 PolarHBondContact O-N 3.42Å; L92-F94 PolarHBondContact O-N 3.4Å; F94-S96 PolarHBondContact O-N 3.24Å; F94-T97 WeakPolarHBondContact O-CB 3.26Å; F94-T97 PolarHBondContact O-N 2.92Å; F94-T97 PolarHBondContact O-OG1 3.42Å; F94-L98 HydrophobicContact CE1-CD2 4.11Å; F94-L98 HydrophobicContact CE2-CD2 4.24Å; F94-L98 HydrophobicContact CZ-CD2 3.71Å; F94-L125 HydrophobicContact CD2-CB 4.32Å; F94-L125 HydrophobicContact CD2-CD1 4.4Å; F94-L125 HydrophobicContact CE2-CB 3.84Å; F94-L125 HydrophobicContact CE2-CD1 3.43Å; F94-L125 VanDerWaalsContact CE2-CD1 3.43Å; F94-L125 HydrophobicContact CE2-CG 4.24Å; F94-L125 HydrophobicContact CZ-CD1 3.52Å; F94-N128 HydrophobicContact CB-CB 3.47Å; F94-N128 VanDerWaalsContact CB-CB 3.47Å; F94-N128 HydrophobicContact CD1-CB 4.46Å; F94-N128 HydrophobicContact CD2-CB 4.4Å; F94-N128 HydrophobicContact CG-CB 3.88Å; F94-A302 HydrophobicContact CE1-CB 3.93Å; F94-A302 HydrophobicContact CZ-CB 3.82Å; F94-T305 HydrophobicContact CD1-CG2 3.78Å; F94-T305 HydrophobicContact CE1-CG2 4.25Å
95	I	98.3	Very high	97.6	Very high	0 Å²	0	24.1 Å²	24.1	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-59.3	-36	-178	-73	159.9	0	0	0	111.1	F56 G59 V60 D91 L92 T97 L98 T305	F56-I95 HydrophobicContact CB-CG2 4.37Å; F56-I95 HydrophobicContact CD2-CG2 3.66Å; F56-I95 WeakPolarHBondContact CD2-O 3.31Å; F56-I95 HydrophobicContact CE2-CG2 4.41Å; F56-I95 HydrophobicContact CG-CG2 4.39Å; G59-I95 VanDerWaalsContact CA-CD1 3.44Å; V60-I95 HydrophobicContact CG2-CG2 3.72Å; D91-I95 HydrophobicContact CB-CD1 4.29Å; D91-I95 VanDerWaalsContact O-CB 3.29Å; D91-I95 WeakPolarHBondContact O-CB 3.26Å; D91-I95 WeakPolarHBondContact O-CD1 3.21Å; D91-I95 WeakPolarHBondContact O-CG1 3.47Å; D91-I95 PolarHBondContact O-N 3.28Å; L92-I95 PolarHBondContact O-N 3.02Å; I95-T97 PolarHBondContact O-N 3.1Å; I95-L98 HydrophobicContact CB-CD1 4.38Å; I95-L98 HydrophobicContact CG1-CD1 4.24Å; I95-L98 HydrophobicContact CG2-CD1 4.24Å; I95-L98 WeakPolarHBondContact O-CB 3.34Å; I95-L98 WeakPolarHBondContact O-CG 3.49Å; I95-L98 PolarHBondContact O-N 3.35Å; I95-T305 HydrophobicContact CD1-CG2 4.27Å; I95-T305 HydrophobicContact CG1-CG2 4.28Å
96	S	97.9	Very high	97.6	Very high	63 Å²	63	28.9 Å²	28.9	44%	0.441	16%	0.155	S	C	.	.	T	Hydrogen-bonded Turn	trans	-57.5	-21.8	175.4	78.1	0	0	0	0	114.1	L92 L93 F94 P99	L92-S96 WeakPolarHBondContact O-CB 3.35Å; L92-S96 PolarHBondContact O-N 2.69Å; L93-S96 PolarHBondContact O-OG 3.46Å; F94-S96 PolarHBondContact O-N 3.24Å; S96-P99 WeakPolarHBondContact O-CD 3.36Å
97	T	97.4	Very high	97.5	Very high	12 Å²	12	34.5 Å²	34.5	7%	0.074	18%	0.176	C	C	.	.	T	Hydrogen-bonded Turn	trans	-88.5	-12.3	178.6	67.6	0	0	0	0	113.5	F94 I95 F100 R101 M121	F94-T97 WeakPolarHBondContact O-CB 3.26Å; F94-T97 PolarHBondContact O-N 2.92Å; F94-T97 PolarHBondContact O-OG1 3.42Å; I95-T97 PolarHBondContact O-N 3.1Å; T97-F100 PolarHBondContact O-N 3.33Å; T97-R101 PolarHBondContact O-N 3.5Å; T97-R101 PolarHBondContact O-NH1 3.33Å; T97-R101 PolarHBondContact OG1-NH1 3.46Å; T97-R101 PolarHBondContact OG1-NH2 2.99Å; T97-M121 HydrophobicContact CG2-CE 4.23Å; T97-M121 HydrophobicContact CG2-SD 4.49Å
98	L	97.7	Very high	97.2	Very high	0 Å²	0	35.4 Å²	35.4	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-64.1	-38.9	-177.8	-66.2	178.2	0	0	0	114.6	Y52 I55 F56 F94 I95 F100 R101 A102	Y52-L98 HydrophobicContact CD1-CD2 3.83Å; Y52-L98 HydrophobicContact CE1-CD2 4.27Å; Y52-L98 HydrophobicContact CG-CD2 4.06Å; I55-L98 HydrophobicContact CB-CD1 3.84Å; I55-L98 HydrophobicContact CG2-CD1 3.42Å; I55-L98 VanDerWaalsContact CG2-CD1 3.42Å; F56-L98 HydrophobicContact CB-CB 4.34Å; F56-L98 HydrophobicContact CB-CD1 4.43Å; F94-L98 HydrophobicContact CE1-CD2 4.11Å; F94-L98 HydrophobicContact CE2-CD2 4.24Å; F94-L98 HydrophobicContact CZ-CD2 3.71Å; I95-L98 HydrophobicContact CB-CD1 4.38Å; I95-L98 HydrophobicContact CG1-CD1 4.24Å; I95-L98 HydrophobicContact CG2-CD1 4.24Å; I95-L98 WeakPolarHBondContact O-CB 3.34Å; I95-L98 WeakPolarHBondContact O-CG 3.49Å; I95-L98 PolarHBondContact O-N 3.35Å; L98-F100 VanDerWaalsContact C-N 3.3Å; L98-F100 PolarHBondContact O-N 2.91Å; L98-R101 PolarHBondContact O-N 3.28Å; L98-R101 VanDerWaalsContact O-N 3.13Å; L98-A102 PolarHBondContact O-N 2.92Å
99	P	97.9	Very high	96.9	Very high	40 Å²	40	35.7 Å²	35.7	26%	0.26	19%	0.187	S	C	.	.	H	α-helix	trans	-59.1	-39.3	177	-26.7	36.5	0	0	0	113.3	F56 S96 R101 A102 D103	F56-P99 HydrophobicContact CD1-CG 4.36Å; F56-P99 HydrophobicContact CD2-CG 3.63Å; F56-P99 HydrophobicContact CE1-CG 4.35Å; F56-P99 HydrophobicContact CE2-CG 3.62Å; F56-P99 HydrophobicContact CG-CG 4.02Å; F56-P99 HydrophobicContact CZ-CG 3.99Å; S96-P99 WeakPolarHBondContact O-CD 3.36Å; P99-R101 VanDerWaalsContact C-N 3.33Å; P99-R101 PolarHBondContact O-N 2.83Å; P99-A102 PolarHBondContact O-N 2.8Å; P99-D103 PolarHBondContact O-N 2.85Å
100	F	97.3	Very high	96.6	Very high	84 Å²	84	34.8 Å²	34.8	37%	0.368	18%	0.183	S	C	.	.	H	α-helix	trans	-63.8	-38.8	176.2	-59.6	-88.1	0	0	0	111.9	T97 L98 Y104 W111 F113 M121	T97-F100 PolarHBondContact O-N 3.33Å; L98-F100 VanDerWaalsContact C-N 3.3Å; L98-F100 PolarHBondContact O-N 2.91Å; F100-Y104 PolarHBondContact O-N 3.28Å; F100-Y104 VanDerWaalsContact O-N 3.08Å; F100-W111 HydrophobicContact CB-CH2 4.13Å; F100-W111 HydrophobicContact CB-CZ3 4.41Å; F100-F113 HydrophobicContact CB-CD2 4.46Å; F100-F113 HydrophobicContact CB-CE2 4.35Å; F100-F113 AromaticContact CD1-CD1 3.82Å; F100-F113 HydrophobicContact CD1-CD1 3.82Å; F100-F113 HydrophobicContact CD1-CD2 4.01Å; F100-F113 AromaticContact CD1-CE1 3.82Å; F100-F113 HydrophobicContact CD1-CE1 3.82Å; F100-F113 HydrophobicContact CD1-CE2 4.01Å; F100-F113 AromaticContact CD1-CG 3.91Å; F100-F113 HydrophobicContact CD1-CG 3.91Å; F100-F113 AromaticContact CD1-CZ 3.91Å; F100-F113 HydrophobicContact CD1-CZ 3.91Å; F100-F113 HydrophobicContact CE1-CD1 4.06Å; F100-F113 HydrophobicContact CE1-CE1 4.1Å; F100-M121 HydrophobicContact CB-CE 4.25Å; F100-M121 HydrophobicContact CB-SD 4.01Å; F100-M121 HydrophobicContact CD2-CE 4.49Å; F100-M121 HydrophobicContact CG-CE 4.41Å
101	R	96.4	Very high	96.5	Very high	3 Å²	3	34.8 Å²	34.8	1%	0.011	18%	0.183	C	C	.	.	H	α-helix	trans	-67.6	-39.1	174.4	-61.1	-165.7	-173.8	79	1	111.9	Y52 T97 L98 P99 Y104 Y105 M121 S124 L195	Y52-R101 HydrophobicContact CD2-CB 3.7Å; Y52-R101 HydrophobicContact CE2-CB 3.63Å; Y52-R101 HydrophobicContact CE2-CG 4.48Å; T97-R101 PolarHBondContact O-N 3.5Å; T97-R101 PolarHBondContact O-NH1 3.33Å; T97-R101 PolarHBondContact OG1-NH1 3.46Å; T97-R101 PolarHBondContact OG1-NH2 2.99Å; L98-R101 PolarHBondContact O-N 3.28Å; L98-R101 VanDerWaalsContact O-N 3.13Å; P99-R101 VanDerWaalsContact C-N 3.33Å; P99-R101 PolarHBondContact O-N 2.83Å; R101-Y104 WeakPolarHBondContact O-CB 3.25Å; R101-Y105 WeakPolarHBondContact O-CD2 3.49Å; R101-Y105 PolarHBondContact O-N 2.89Å; R101-M121 HydrophobicContact CG-SD 4.13Å; R101-M121 PolarHBondContact NH2-O 3.17Å; R101-S124 PolarHBondContact NH2-OG 3.41Å; R101-S124 VanDerWaalsContact NH2-OG 3.12Å; R101-L195 HydrophobicContact CB-CD1 4.48Å; R101-L195 HydrophobicContact CG-CD1 3.97Å
102	A	97.5	Very high	96.3	Very high	2 Å²	2	39 Å²	39	2%	0.017	21%	0.205	C	C	.	.	H	α-helix	trans	-63.9	-47.5	176.4	0	0	0	0	0	111.2	P49 L53 L98 P99 Y104 Y105 L106	P49-A102 HydrophobicContact CB-CB 4.25Å; L53-A102 HydrophobicContact CD2-CB 4.22Å; L53-A102 HydrophobicContact CG-CB 4.12Å; L98-A102 PolarHBondContact O-N 2.92Å; P99-A102 PolarHBondContact O-N 2.8Å; A102-Y104 VanDerWaalsContact C-N 3.34Å; A102-Y104 PolarHBondContact O-N 2.98Å; A102-Y105 PolarHBondContact O-N 3.17Å; A102-L106 WeakPolarHBondContact O-CG 3.19Å; A102-L106 PolarHBondContact O-N 2.92Å
103	D	97.8	Very high	96.1	Very high	40 Å²	40	40.3 Å²	40.3	21%	0.214	21%	0.208	C	C	.	.	H	α-helix	trans	-58.8	-43.5	177.5	179.2	84.3	0	0	0	111.9	P99 Y105 L106 R107 F113	P99-D103 PolarHBondContact O-N 2.85Å; D103-Y105 VanDerWaalsContact C-N 3.34Å; D103-Y105 PolarHBondContact O-N 2.94Å; D103-L106 PolarHBondContact O-N 2.92Å; D103-L106 VanDerWaalsContact O-N 3.17Å; D103-R107 VanDerWaalsContact CG-NE 3.28Å; D103-R107 WeakPolarHBondContact O-CG 3.45Å; D103-R107 PolarHBondContact O-N 3.33Å; D103-R107 IonicContact OD1-CZ 2.68Å; D103-R107 IonicContact OD1-NE 2.96Å; D103-R107 PolarHBondContact OD1-NE 2.72Å; D103-R107 VanDerWaalsContact OD1-NE 3.12Å; D103-R107 IonicContact OD1-NH2 3.47Å; D103-R107 PolarHBondContact OD1-NH2 3.22Å; D103-R107 WeakPolarHBondContact OD2-CD 3.47Å; D103-R107 IonicContact OD2-CZ 3.19Å; D103-R107 IonicContact OD2-NE 3.74Å; D103-R107 PolarHBondContact OD2-NE 2.91Å; D103-R107 IonicContact OD2-NH2 3.7Å; D103-F113 HydrophobicContact CB-CE2 4.27Å; D103-F113 HydrophobicContact CB-CZ 4.21Å; D103-F113 VanDerWaalsContact OD2-CE2 3.27Å; D103-F113 WeakPolarHBondContact OD2-CE2 3.48Å; D103-F113 WeakPolarHBondContact OD2-CZ 3.27Å
104	Y	95.8	Very high	95.9	Very high	1 Å²	1	37.3 Å²	37.3	0%	0.004	20%	0.202	C	C	.	.	H	α-helix	trans	-51.3	-49.6	173.7	170.9	-111.1	0	0	0	113	F100 R101 A102 R107 S109 D110 W111 S193 C194 L195	F100-Y104 PolarHBondContact O-N 3.28Å; F100-Y104 VanDerWaalsContact O-N 3.08Å; R101-Y104 WeakPolarHBondContact O-CB 3.25Å; A102-Y104 VanDerWaalsContact C-N 3.34Å; A102-Y104 PolarHBondContact O-N 2.98Å; Y104-R107 PolarHBondContact O-N 2.97Å; Y104-S109 WeakPolarHBondContact CE2-O 3.3Å; Y104-S109 VanDerWaalsContact O-CA 3.23Å; Y104-S109 WeakPolarHBondContact O-CA 3.4Å; Y104-S109 PolarHBondContact O-N 2.77Å; Y104-S109 PolarHBondContact OH-O 2.93Å; Y104-D110 PolarHBondContact O-N 2.76Å; Y104-W111 HydrophobicContact CD2-CB 3.83Å; Y104-W111 AromaticContact CD2-CE3 3.88Å; Y104-W111 HydrophobicContact CD2-CE3 3.88Å; Y104-W111 HydrophobicContact CE2-CB 3.94Å; Y104-W111 HydrophobicContact CG-CE3 4.06Å; Y104-S193 PolarHBondContact OH-OG 3.02Å; Y104-C194 WeakPolarHBondContact CE1-O 3.4Å; Y104-C194 HydrophobicContact CE2-CB 4.24Å; Y104-C194 PolarHBondContact OH-N 3.17Å; Y104-C194 VanDerWaalsContact OH-N 3.16Å; Y104-C194 PolarHBondContact OH-O 2.92Å; Y104-L195 HydrophobicContact CD1-CD1 4.38Å
105	Y	95	Very high	95.6	Very high	12 Å²	12	40 Å²	40	5%	0.047	22%	0.216	C	C	.	.	H	α-helix	trans	-71.7	-34.9	-179.7	-76.3	-61.8	0	0	0	112.7	K44 R45 F48 Y52 R101 A102 D103 R107 G108	K44-Y105 HydrophobicContact CB-CD1 4.33Å; K44-Y105 HydrophobicContact CB-CE1 4Å; R45-Y105 HydrophobicContact CG-CD1 4.43Å; F48-Y105 HydrophobicContact CB-CD2 3.49Å; F48-Y105 VanDerWaalsContact CB-CD2 3.49Å; F48-Y105 HydrophobicContact CB-CE2 3.76Å; F48-Y105 HydrophobicContact CB-CG 4.05Å; F48-Y105 HydrophobicContact CD2-CD1 4.18Å; F48-Y105 AromaticContact CD2-CD2 3.84Å; F48-Y105 HydrophobicContact CD2-CD2 3.84Å; F48-Y105 AromaticContact CD2-CE1 3.72Å; F48-Y105 HydrophobicContact CD2-CE1 3.72Å; F48-Y105 AromaticContact CD2-CE2 3.34Å; F48-Y105 HydrophobicContact CD2-CE2 3.34Å; F48-Y105 HydrophobicContact CD2-CG 4.25Å; F48-Y105 AromaticContact CD2-CZ 3.26Å; F48-Y105 HydrophobicContact CE2-CE1 4.17Å; F48-Y105 HydrophobicContact CE2-CE2 4Å; F48-Y105 AromaticContact CE2-CZ 3.6Å; F48-Y105 WeakPolarHBondContact CE2-OH 3.44Å; F48-Y105 HydrophobicContact CG-CD2 4.01Å; F48-Y105 AromaticContact CG-CE2 3.74Å; F48-Y105 HydrophobicContact CG-CE2 3.74Å; Y52-Y105 HydrophobicContact CE2-CD2 4.33Å; Y52-Y105 HydrophobicContact CE2-CE2 4.06Å; R101-Y105 WeakPolarHBondContact O-CD2 3.49Å; R101-Y105 PolarHBondContact O-N 2.89Å; A102-Y105 PolarHBondContact O-N 3.17Å; D103-Y105 VanDerWaalsContact C-N 3.34Å; D103-Y105 PolarHBondContact O-N 2.94Å; Y105-R107 VanDerWaalsContact C-N 3.3Å; Y105-R107 PolarHBondContact O-N 3.04Å; Y105-G108 PolarHBondContact O-N 3.31Å; Y105-G108 VanDerWaalsContact O-N 3.17Å
106	L	96.3	Very high	95.4	Very high	119 Å²	119	45.9 Å²	45.9	62%	0.623	25%	0.247	S	C	*	.	H	α-helix	trans	-66.6	-30	175.2	-70.6	171.8	0	0	0	112.8	P49 A102 D103 G108	P49-L106 HydrophobicContact CB-CD1 4.25Å; P49-L106 HydrophobicContact CB-CD2 3.81Å; P49-L106 HydrophobicContact CB-CG 3.8Å; P49-L106 HydrophobicContact CG-CD2 3.84Å; P49-L106 HydrophobicContact CG-CG 3.79Å; A102-L106 WeakPolarHBondContact O-CG 3.19Å; A102-L106 PolarHBondContact O-N 2.92Å; D103-L106 PolarHBondContact O-N 2.92Å; D103-L106 VanDerWaalsContact O-N 3.17Å; L106-G108 PolarHBondContact O-N 3.45Å
107	R	94.9	Very high	95.2	Very high	128 Å²	128	44 Å²	44	48%	0.483	24%	0.236	S	C	.	.	T	Hydrogen-bonded Turn	trans	-79.2	10.9	173.7	-68.5	-179.5	-171.2	-77	-16	113.9	D103 Y104 Y105 D110	D103-R107 VanDerWaalsContact CG-NE 3.28Å; D103-R107 WeakPolarHBondContact O-CG 3.45Å; D103-R107 PolarHBondContact O-N 3.33Å; D103-R107 IonicContact OD1-CZ 2.68Å; D103-R107 IonicContact OD1-NE 2.96Å; D103-R107 PolarHBondContact OD1-NE 2.72Å; D103-R107 VanDerWaalsContact OD1-NE 3.12Å; D103-R107 IonicContact OD1-NH2 3.47Å; D103-R107 PolarHBondContact OD1-NH2 3.22Å; D103-R107 WeakPolarHBondContact OD2-CD 3.47Å; D103-R107 IonicContact OD2-CZ 3.19Å; D103-R107 IonicContact OD2-NE 3.74Å; D103-R107 PolarHBondContact OD2-NE 2.91Å; D103-R107 IonicContact OD2-NH2 3.7Å; Y104-R107 PolarHBondContact O-N 2.97Å; Y105-R107 VanDerWaalsContact C-N 3.3Å; Y105-R107 PolarHBondContact O-N 3.04Å; R107-D110 HydrophobicContact CB-CB 4.28Å
108	G	91.8	Very high	95	Very high	21 Å²	21	43.6 Å²	43.6	22%	0.216	23%	0.233	C	C	.	.	T	Hydrogen-bonded Turn	trans	73.4	36.5	-176.5	0	0	0	0	0	112.7	R45 Y105 L106	R45-G108 VanDerWaalsContact CZ-O 3.22Å; R45-G108 PolarHBondContact NE-O 3.19Å; R45-G108 PolarHBondContact NH2-O 2.92Å; Y105-G108 PolarHBondContact O-N 3.31Å; Y105-G108 VanDerWaalsContact O-N 3.17Å; L106-G108 PolarHBondContact O-N 3.45Å
109	S	91.8	Very high	94.7	Very high	6 Å²	6	46.6 Å²	46.6	4%	0.042	24%	0.244	C	C	.	.	S	Bend	trans	66.6	40.3	-178.7	-43	0	0	0	0	113.1	R45 Y104	R45-S109 PolarHBondContact NE-OG 3.24Å; R45-S109 VanDerWaalsContact NE-OG 3.12Å; Y104-S109 WeakPolarHBondContact CE2-O 3.3Å; Y104-S109 VanDerWaalsContact O-CA 3.23Å; Y104-S109 WeakPolarHBondContact O-CA 3.4Å; Y104-S109 PolarHBondContact O-N 2.77Å; Y104-S109 PolarHBondContact OH-O 2.93Å
110	D	93.6	Very high	94.6	Very high	44 Å²	44	48 Å²	48	24%	0.235	25%	0.249	C	C	.	.			trans	-112.8	119.2	175	-172.1	32.3	0	0	0	111.1	Y104 R107 V191 I192	Y104-D110 PolarHBondContact O-N 2.76Å; R107-D110 HydrophobicContact CB-CB 4.28Å; D110-V191 HydrophobicContact CB-CB 4.34Å; D110-V191 HydrophobicContact CB-CG1 3.97Å; D110-I192 PolarHBondContact OD1-N 3.28Å
111	W	94.8	Very high	94.4	Very high	2 Å²	2	44.5 Å²	44.5	1%	0.008	23%	0.234	C	C	.	.			trans	-96.6	113.7	-172.5	-177.8	-95.9	0	0	0	112.5	F100 Y104 F113 G114 A117 C118 M121 I192 C194	F100-W111 HydrophobicContact CB-CH2 4.13Å; F100-W111 HydrophobicContact CB-CZ3 4.41Å; Y104-W111 HydrophobicContact CD2-CB 3.83Å; Y104-W111 AromaticContact CD2-CE3 3.88Å; Y104-W111 HydrophobicContact CD2-CE3 3.88Å; Y104-W111 HydrophobicContact CE2-CB 3.94Å; Y104-W111 HydrophobicContact CG-CE3 4.06Å; W111-F113 HydrophobicContact CD2-CD2 4.23Å; W111-F113 HydrophobicContact CE3-CD2 4.08Å; W111-F113 HydrophobicContact CH2-CB 4.23Å; W111-F113 AromaticContact CH2-CD2 3.76Å; W111-F113 HydrophobicContact CH2-CD2 3.76Å; W111-F113 HydrophobicContact CH2-CG 4.4Å; W111-F113 HydrophobicContact CZ2-CB 3.63Å; W111-F113 AromaticContact CZ2-CD2 3.95Å; W111-F113 HydrophobicContact CZ2-CD2 3.95Å; W111-F113 HydrophobicContact CZ2-CG 4.25Å; W111-F113 AromaticContact CZ3-CD2 3.83Å; W111-F113 HydrophobicContact CZ3-CD2 3.83Å; W111-F113 HydrophobicContact CZ3-CE2 4.46Å; W111-G114 PolarHBondContact NE1-O 3.38Å; W111-A117 HydrophobicContact CZ2-CB 3.67Å; W111-C118 HydrophobicContact CD2-CB 4.45Å; W111-C118 HydrophobicContact CZ2-CB 4.22Å; W111-M121 HydrophobicContact CH2-CE 4.2Å; W111-M121 HydrophobicContact CH2-CG 3.41Å; W111-M121 VanDerWaalsContact CH2-CG 3.41Å; W111-M121 HydrophobicContact CH2-SD 4.02Å; W111-M121 HydrophobicContact CZ2-CG 4.1Å; W111-M121 HydrophobicContact CZ3-CG 4.05Å; W111-I192 HydrophobicContact CB-CB 4.46Å; W111-I192 HydrophobicContact CB-CG2 4.16Å; W111-I192 VanDerWaalsContact CB-O 3.26Å; W111-I192 WeakPolarHBondContact CB-O 3.46Å; W111-I192 PolarHBondContact N-O 3.12Å; W111-C194 HydrophobicContact CB-CB 3.8Å; W111-C194 HydrophobicContact CD2-CB 3.81Å; W111-C194 HydrophobicContact CE3-CB 4.01Å; W111-C194 HydrophobicContact CG-CB 3.72Å
112	I	95.6	Very high	94	Very high	90 Å²	90	45.5 Å²	45.5	46%	0.462	24%	0.241	S	C	.	.			trans	-106.8	-5.2	-174.6	63.7	165.8	0	0	0	114.9	G114	I112-G114 VanDerWaalsContact C-N 3.3Å; I112-G114 PolarHBondContact O-N 3.4Å
113	F	94.8	Very high	93.8	Very high	75 Å²	75	47.2 Å²	47.2	33%	0.329	25%	0.248	S	C	.	.	S	Bend	trans	-89.5	9.2	-171.6	-54.4	-75.4	0	0	0	114.1	F100 D103 W111 A117	F100-F113 HydrophobicContact CB-CD2 4.46Å; F100-F113 HydrophobicContact CB-CE2 4.35Å; F100-F113 AromaticContact CD1-CD1 3.82Å; F100-F113 HydrophobicContact CD1-CD1 3.82Å; F100-F113 HydrophobicContact CD1-CD2 4.01Å; F100-F113 AromaticContact CD1-CE1 3.82Å; F100-F113 HydrophobicContact CD1-CE1 3.82Å; F100-F113 HydrophobicContact CD1-CE2 4.01Å; F100-F113 AromaticContact CD1-CG 3.91Å; F100-F113 HydrophobicContact CD1-CG 3.91Å; F100-F113 AromaticContact CD1-CZ 3.91Å; F100-F113 HydrophobicContact CD1-CZ 3.91Å; F100-F113 HydrophobicContact CE1-CD1 4.06Å; F100-F113 HydrophobicContact CE1-CE1 4.1Å; D103-F113 HydrophobicContact CB-CE2 4.27Å; D103-F113 HydrophobicContact CB-CZ 4.21Å; D103-F113 VanDerWaalsContact OD2-CE2 3.27Å; D103-F113 WeakPolarHBondContact OD2-CE2 3.48Å; D103-F113 WeakPolarHBondContact OD2-CZ 3.27Å; W111-F113 HydrophobicContact CD2-CD2 4.23Å; W111-F113 HydrophobicContact CE3-CD2 4.08Å; W111-F113 HydrophobicContact CH2-CB 4.23Å; W111-F113 AromaticContact CH2-CD2 3.76Å; W111-F113 HydrophobicContact CH2-CD2 3.76Å; W111-F113 HydrophobicContact CH2-CG 4.4Å; W111-F113 HydrophobicContact CZ2-CB 3.63Å; W111-F113 AromaticContact CZ2-CD2 3.95Å; W111-F113 HydrophobicContact CZ2-CD2 3.95Å; W111-F113 HydrophobicContact CZ2-CG 4.25Å; W111-F113 AromaticContact CZ3-CD2 3.83Å; W111-F113 HydrophobicContact CZ3-CD2 3.83Å; W111-F113 HydrophobicContact CZ3-CE2 4.46Å; F113-A117 HydrophobicContact CB-CB 3.95Å; F113-A117 VanDerWaalsContact O-CB 3.27Å; F113-A117 WeakPolarHBondContact O-CB 3.46Å
114	G	93.8	Very high	93.7	Very high	38 Å²	38	46.2 Å²	46.2	39%	0.392	24%	0.244	S	C	.	.			trans	80.9	162.6	179.3	0	0	0	0	0	114.8	W111 I112 L116 A117 C118	W111-G114 PolarHBondContact NE1-O 3.38Å; I112-G114 VanDerWaalsContact C-N 3.3Å; I112-G114 PolarHBondContact O-N 3.4Å; G114-L116 PolarHBondContact O-N 2.91Å; G114-A117 PolarHBondContact O-N 3.06Å; G114-C118 PolarHBondContact O-N 3.29Å
115	D	92.1	Very high	93.6	Very high	60 Å²	60	47.3 Å²	47.3	32%	0.321	25%	0.249	S	C	.	.	H	α-helix	trans	-61.7	-42.9	-171	-179.4	61.4	0	0	0	113.4	A117 C118 R119 G184 S185	D115-A117 VanDerWaalsContact C-N 3.33Å; D115-A117 PolarHBondContact O-N 2.97Å; D115-C118 WeakPolarHBondContact O-CB 3.38Å; D115-C118 PolarHBondContact O-N 3.49Å; D115-C118 VanDerWaalsContact O-N 3.14Å; D115-R119 WeakPolarHBondContact O-CG 3.39Å; D115-R119 PolarHBondContact O-N 3.44Å; D115-R119 VanDerWaalsContact O-N 3.1Å; D115-R119 IonicContact OD1-CZ 3.94Å; D115-R119 IonicContact OD1-NE 3.68Å; D115-R119 IonicContact OD1-NH2 3.47Å; D115-R119 PolarHBondContact OD1-NH2 2.92Å; D115-R119 IonicContact OD2-CZ 3.2Å; D115-R119 IonicContact OD2-NE 2.71Å; D115-R119 PolarHBondContact OD2-NE 2.69Å; D115-R119 IonicContact OD2-NH2 2.82Å; D115-R119 PolarHBondContact OD2-NH2 3.22Å; D115-G184 WeakPolarHBondContact OD1-CA 3.29Å; D115-S185 WeakPolarHBondContact CA-OG 3.32Å; D115-S185 PolarHBondContact OD1-N 3.41Å; D115-S185 PolarHBondContact OD1-OG 3.41Å
116	L	92.9	Very high	93.5	Very high	124 Å²	124	48.1 Å²	48.1	65%	0.649	25%	0.253	S	S	*	.	H	α-helix	trans	-59.8	-44	179.2	178.9	61.7	0	0	0	111.9	G114 C118 R119 I120	G114-L116 PolarHBondContact O-N 2.91Å; L116-C118 VanDerWaalsContact C-N 3.3Å; L116-C118 PolarHBondContact O-N 3.29Å; L116-R119 PolarHBondContact O-N 2.98Å; L116-I120 HydrophobicContact CD1-CD1 4.32Å; L116-I120 HydrophobicContact CG-CD1 4.07Å; L116-I120 WeakPolarHBondContact O-CG1 3.44Å; L116-I120 PolarHBondContact O-N 3.46Å; L116-I120 VanDerWaalsContact O-N 3.09Å
117	A	94.4	Very high	93.5	Very high	24 Å²	24	42.9 Å²	42.9	20%	0.198	23%	0.226	C	C	.	.	H	α-helix	trans	-64.1	-37.9	178.5	0	0	0	0	0	111	W111 F113 G114 D115 R119 I120 M121	W111-A117 HydrophobicContact CZ2-CB 3.67Å; F113-A117 HydrophobicContact CB-CB 3.95Å; F113-A117 VanDerWaalsContact O-CB 3.27Å; F113-A117 WeakPolarHBondContact O-CB 3.46Å; G114-A117 PolarHBondContact O-N 3.06Å; D115-A117 VanDerWaalsContact C-N 3.33Å; D115-A117 PolarHBondContact O-N 2.97Å; A117-R119 PolarHBondContact O-N 3.3Å; A117-I120 PolarHBondContact O-N 3.41Å; A117-M121 WeakPolarHBondContact O-CE 3.33Å; A117-M121 WeakPolarHBondContact O-CG 3.33Å; A117-M121 PolarHBondContact O-N 2.79Å
118	C	93.3	Very high	93.7	Very high	2 Å²	2	37 Å²	37	1%	0.014	20%	0.204	C	C	.	.	H	α-helix	trans	-59.5	-46.5	175.5	179.8	0	0	0	0	111.9	W111 G114 D115 L116 I120 M121 C194	W111-C118 HydrophobicContact CD2-CB 4.45Å; W111-C118 HydrophobicContact CZ2-CB 4.22Å; G114-C118 PolarHBondContact O-N 3.29Å; D115-C118 WeakPolarHBondContact O-CB 3.38Å; D115-C118 PolarHBondContact O-N 3.49Å; D115-C118 VanDerWaalsContact O-N 3.14Å; L116-C118 VanDerWaalsContact C-N 3.3Å; L116-C118 PolarHBondContact O-N 3.29Å; C118-I120 VanDerWaalsContact C-N 3.3Å; C118-I120 PolarHBondContact O-N 3.08Å; C118-M121 WeakPolarHBondContact O-CB 3.5Å; C118-M121 PolarHBondContact O-N 3.45Å; C118-M121 VanDerWaalsContact O-N 3.1Å; C118-C194 WeakPolarHBondContact CA-SG 3.35Å; C118-C194 HydrophobicContact CB-CB 4.03Å; C118-C194 WeakPolarHBondContact CB-SG 3.44Å; C118-C194 WeakPolarHBondContact SG-CB 3.33Å; C118-C194 CovalentContact SG-SG 2.02Å; C118-C194 PolarHBondContact SG-SG 3.43Å
119	R	92.2	Very high	93.9	Very high	64 Å²	64	36.2 Å²	36.2	24%	0.242	19%	0.194	C	C	.	.	H	α-helix	trans	-57.9	-43.8	176.1	-65.5	169.7	-172.1	-80.3	-7.6	111.4	D115 L116 A117 M121 S122 Y123 L181 N182	D115-R119 WeakPolarHBondContact O-CG 3.39Å; D115-R119 PolarHBondContact O-N 3.44Å; D115-R119 VanDerWaalsContact O-N 3.1Å; D115-R119 IonicContact OD1-CZ 3.94Å; D115-R119 IonicContact OD1-NE 3.68Å; D115-R119 IonicContact OD1-NH2 3.47Å; D115-R119 PolarHBondContact OD1-NH2 2.92Å; D115-R119 IonicContact OD2-CZ 3.2Å; D115-R119 IonicContact OD2-NE 2.71Å; D115-R119 PolarHBondContact OD2-NE 2.69Å; D115-R119 IonicContact OD2-NH2 2.82Å; D115-R119 PolarHBondContact OD2-NH2 3.22Å; L116-R119 PolarHBondContact O-N 2.98Å; A117-R119 PolarHBondContact O-N 3.3Å; R119-M121 VanDerWaalsContact C-N 3.3Å; R119-M121 PolarHBondContact O-N 3.23Å; R119-S122 PolarHBondContact O-N 2.94Å; R119-Y123 WeakPolarHBondContact O-CB 3.5Å; R119-Y123 PolarHBondContact O-N 3.46Å; R119-Y123 VanDerWaalsContact O-N 3.12Å; R119-L181 HydrophobicContact CB-CD2 4.02Å; R119-L181 WeakPolarHBondContact CD-O 3.49Å; R119-L181 WeakPolarHBondContact CG-O 3.04Å; R119-L181 PolarHBondContact NH1-O 3.38Å; R119-N182 PolarHBondContact NH1-O 2.87Å
120	I	94.3	Very high	94.1	Very high	70 Å²	70	36.7 Å²	36.7	36%	0.359	20%	0.196	S	C	.	.	H	α-helix	trans	-63.2	-34.2	178	-68.1	167.6	0	0	0	111.5	L116 A117 C118 Y123 S124	L116-I120 HydrophobicContact CD1-CD1 4.32Å; L116-I120 HydrophobicContact CG-CD1 4.07Å; L116-I120 WeakPolarHBondContact O-CG1 3.44Å; L116-I120 PolarHBondContact O-N 3.46Å; L116-I120 VanDerWaalsContact O-N 3.09Å; A117-I120 PolarHBondContact O-N 3.41Å; C118-I120 VanDerWaalsContact C-N 3.3Å; C118-I120 PolarHBondContact O-N 3.08Å; I120-Y123 PolarHBondContact O-N 2.96Å; I120-S124 VanDerWaalsContact O-CB 3.24Å; I120-S124 WeakPolarHBondContact O-CB 3.5Å; I120-S124 PolarHBondContact O-N 2.92Å; I120-S124 PolarHBondContact O-OG 3.37Å
121	M	93.3	Very high	94.3	Very high	9 Å²	9	34.6 Å²	34.6	4%	0.044	18%	0.184	C	C	.	.	H	α-helix	trans	-61.9	-50.6	179.2	-63.1	-55.9	116.9	0	0	111.6	T97 F100 R101 W111 A117 C118 R119 S124 L125 L195	T97-M121 HydrophobicContact CG2-CE 4.23Å; T97-M121 HydrophobicContact CG2-SD 4.49Å; F100-M121 HydrophobicContact CB-CE 4.25Å; F100-M121 HydrophobicContact CB-SD 4.01Å; F100-M121 HydrophobicContact CD2-CE 4.49Å; F100-M121 HydrophobicContact CG-CE 4.41Å; R101-M121 HydrophobicContact CG-SD 4.13Å; R101-M121 PolarHBondContact NH2-O 3.17Å; W111-M121 HydrophobicContact CH2-CE 4.2Å; W111-M121 HydrophobicContact CH2-CG 3.41Å; W111-M121 VanDerWaalsContact CH2-CG 3.41Å; W111-M121 HydrophobicContact CH2-SD 4.02Å; W111-M121 HydrophobicContact CZ2-CG 4.1Å; W111-M121 HydrophobicContact CZ3-CG 4.05Å; A117-M121 WeakPolarHBondContact O-CE 3.33Å; A117-M121 WeakPolarHBondContact O-CG 3.33Å; A117-M121 PolarHBondContact O-N 2.79Å; C118-M121 WeakPolarHBondContact O-CB 3.5Å; C118-M121 PolarHBondContact O-N 3.45Å; C118-M121 VanDerWaalsContact O-N 3.1Å; R119-M121 VanDerWaalsContact C-N 3.3Å; R119-M121 PolarHBondContact O-N 3.23Å; M121-S124 PolarHBondContact O-OG 3.08Å; M121-S124 VanDerWaalsContact O-OG 3.07Å; M121-L125 PolarHBondContact O-N 2.93Å; M121-L195 HydrophobicContact CB-CD2 3.66Å; M121-L195 HydrophobicContact CB-CG 4.47Å
122	S	88.4	Confident	94.4	Very high	24 Å²	24	34.5 Å²	34.5	17%	0.168	18%	0.184	C	C	.	.	H	α-helix	trans	-65.3	-45.2	177.1	-69.4	0	0	0	0	111.1	R119 S124 L125 Y126	R119-S122 PolarHBondContact O-N 2.94Å; S122-S124 PolarHBondContact O-N 2.98Å; S122-L125 PolarHBondContact O-N 2.91Å; S122-Y126 VanDerWaalsContact O-CD2 3.31Å; S122-Y126 WeakPolarHBondContact O-CD2 3.49Å; S122-Y126 PolarHBondContact O-N 3.44Å
123	Y	93	Very high	94.5	Very high	39 Å²	39	30.2 Å²	30.2	15%	0.153	16%	0.162	C	C	.	.	H	α-helix	trans	-57.7	-50.7	-178.7	-179.2	-103.9	0	0	0	113.1	R119 I120 L125 Y126 V127 M174 S177 L181	R119-Y123 WeakPolarHBondContact O-CB 3.5Å; R119-Y123 PolarHBondContact O-N 3.46Å; R119-Y123 VanDerWaalsContact O-N 3.12Å; I120-Y123 PolarHBondContact O-N 2.96Å; Y123-L125 VanDerWaalsContact C-N 3.34Å; Y123-L125 PolarHBondContact O-N 3.22Å; Y123-Y126 PolarHBondContact O-N 3.15Å; Y123-V127 HydrophobicContact CD1-CG2 4.15Å; Y123-V127 HydrophobicContact CD2-CG2 4.14Å; Y123-V127 HydrophobicContact CE1-CG2 3.81Å; Y123-V127 HydrophobicContact CE2-CG2 3.8Å; Y123-V127 HydrophobicContact CG-CG2 4.31Å; Y123-V127 WeakPolarHBondContact O-CG2 3.19Å; Y123-V127 PolarHBondContact O-N 2.92Å; Y123-M174 VanDerWaalsContact OH-CA 3.3Å; Y123-M174 WeakPolarHBondContact OH-CA 3.3Å; Y123-M174 WeakPolarHBondContact OH-CB 3.43Å; Y123-M174 WeakPolarHBondContact OH-CG 3.32Å; Y123-M174 PolarHBondContact OH-O 3.34Å; Y123-S177 WeakPolarHBondContact CD2-O 3.29Å; Y123-L181 HydrophobicContact CD1-CD2 4.25Å; Y123-L181 HydrophobicContact CD2-CD1 4.08Å; Y123-L181 HydrophobicContact CD2-CD2 4.04Å; Y123-L181 HydrophobicContact CD2-CG 3.72Å; Y123-L181 HydrophobicContact CE2-CD1 4.14Å; Y123-L181 HydrophobicContact CE2-CG 4.27Å; Y123-L181 HydrophobicContact CG-CD1 4.41Å; Y123-L181 HydrophobicContact CG-CD2 3.7Å; Y123-L181 HydrophobicContact CG-CG 3.95Å
124	S	95.9	Very high	94.6	Very high	19 Å²	19	28.3 Å²	28.3	13%	0.133	15%	0.153	C	C	.	.	H	α-helix	trans	-60.2	-39.1	-178.4	56.4	0	0	0	0	113.3	R101 I120 M121 S122 N128	R101-S124 PolarHBondContact NH2-OG 3.41Å; R101-S124 VanDerWaalsContact NH2-OG 3.12Å; I120-S124 VanDerWaalsContact O-CB 3.24Å; I120-S124 WeakPolarHBondContact O-CB 3.5Å; I120-S124 PolarHBondContact O-N 2.92Å; I120-S124 PolarHBondContact O-OG 3.37Å; M121-S124 PolarHBondContact O-OG 3.08Å; M121-S124 VanDerWaalsContact O-OG 3.07Å; S122-S124 PolarHBondContact O-N 2.98Å; S124-N128 WeakPolarHBondContact O-CB 3.28Å; S124-N128 PolarHBondContact O-N 3.12Å
125	L	93.7	Very high	94.7	Very high	23 Å²	23	26.6 Å²	26.6	12%	0.12	14%	0.135	C	C	.	.	H	α-helix	trans	-59.4	-51	177.4	172	69.5	0	0	0	111.5	F94 M121 S122 Y123 N128 M129 L298	F94-L125 HydrophobicContact CD2-CB 4.32Å; F94-L125 HydrophobicContact CD2-CD1 4.4Å; F94-L125 HydrophobicContact CE2-CB 3.84Å; F94-L125 HydrophobicContact CE2-CD1 3.43Å; F94-L125 VanDerWaalsContact CE2-CD1 3.43Å; F94-L125 HydrophobicContact CE2-CG 4.24Å; F94-L125 HydrophobicContact CZ-CD1 3.52Å; M121-L125 PolarHBondContact O-N 2.93Å; S122-L125 PolarHBondContact O-N 2.91Å; Y123-L125 VanDerWaalsContact C-N 3.34Å; Y123-L125 PolarHBondContact O-N 3.22Å; L125-N128 PolarHBondContact O-N 3.33Å; L125-M129 WeakPolarHBondContact O-CB 3.45Å; L125-M129 PolarHBondContact O-N 3.37Å; L125-L298 HydrophobicContact CD2-CD1 3.92Å
126	Y	93.1	Very high	94.8	Very high	29 Å²	29	23.8 Å²	23.8	11%	0.114	12%	0.119	C	C	.	.	H	α-helix	trans	-75.3	-36.6	-175.6	-74.8	-82	0	0	0	112.2	S122 Y123 N128 M129 Y130 L180 Y270 R274	S122-Y126 VanDerWaalsContact O-CD2 3.31Å; S122-Y126 WeakPolarHBondContact O-CD2 3.49Å; S122-Y126 PolarHBondContact O-N 3.44Å; Y123-Y126 PolarHBondContact O-N 3.15Å; Y126-N128 VanDerWaalsContact C-N 3.33Å; Y126-N128 PolarHBondContact O-N 2.89Å; Y126-M129 HydrophobicContact CD1-CE 3.96Å; Y126-M129 HydrophobicContact CE1-CE 4.31Å; Y126-M129 PolarHBondContact O-N 3.2Å; Y126-Y130 AromaticContact CD1-CE2 3.73Å; Y126-Y130 HydrophobicContact CD1-CE2 3.73Å; Y126-Y130 HydrophobicContact CG-CE2 4.32Å; Y126-Y130 WeakPolarHBondContact O-CD2 3.26Å; Y126-Y130 PolarHBondContact O-N 3.34Å; Y126-L180 HydrophobicContact CD2-CD1 3.35Å; Y126-L180 HydrophobicContact CD2-CD2 4.43Å; Y126-L180 HydrophobicContact CE2-CD1 4.15Å; Y126-L180 HydrophobicContact CE2-CD2 4.46Å; Y126-L180 HydrophobicContact CG-CD1 3.64Å; Y126-Y270 PolarHBondContact OH-OH 2.94Å; Y126-Y270 VanDerWaalsContact OH-OH 3.07Å; Y126-R274 PolarHBondContact OH-NE 2.95Å; Y126-R274 PolarHBondContact OH-NH2 3.45Å; Y126-R274 VanDerWaalsContact OH-NH2 3.11Å
127	V	96.6	Very high	94.9	Very high	10 Å²	10	18.4 Å²	18.4	6%	0.061	9%	0.092	C	C	.	.	H	α-helix	trans	-59.8	-45.4	171.9	173.2	0	0	0	0	110.4	Y123 S131 W170 M174	Y123-V127 HydrophobicContact CD1-CG2 4.15Å; Y123-V127 HydrophobicContact CD2-CG2 4.14Å; Y123-V127 HydrophobicContact CE1-CG2 3.81Å; Y123-V127 HydrophobicContact CE2-CG2 3.8Å; Y123-V127 HydrophobicContact CG-CG2 4.31Å; Y123-V127 WeakPolarHBondContact O-CG2 3.19Å; Y123-V127 PolarHBondContact O-N 2.92Å; V127-S131 WeakPolarHBondContact O-CB 3.41Å; V127-S131 PolarHBondContact O-N 3.49Å; V127-S131 PolarHBondContact O-OG 3.35Å; V127-W170 HydrophobicContact CG1-CE3 4.41Å; V127-W170 HydrophobicContact CG1-CZ3 3.96Å; V127-M174 HydrophobicContact CG1-CG 4.1Å; V127-M174 HydrophobicContact CG2-CG 4.48Å
128	N	97.8	Very high	94.8	Very high	3 Å²	3	18.3 Å²	18.3	2%	0.016	9%	0.089	C	C	.	.	H	α-helix	trans	-62.9	-48.1	175.4	169.8	-99.6	0	0	0	112.3	S90 D91 F94 S124 L125 Y126 Y130 S131 S132	S90-N128 PolarHBondContact O-ND2 3.09Å; S90-N128 PolarHBondContact OG-ND2 2.83Å; D91-N128 WeakPolarHBondContact CA-ND2 3.38Å; D91-N128 PolarHBondContact N-ND2 2.77Å; D91-N128 PolarHBondContact OD1-ND2 3.28Å; F94-N128 HydrophobicContact CB-CB 3.47Å; F94-N128 VanDerWaalsContact CB-CB 3.47Å; F94-N128 HydrophobicContact CD1-CB 4.46Å; F94-N128 HydrophobicContact CD2-CB 4.4Å; F94-N128 HydrophobicContact CG-CB 3.88Å; S124-N128 WeakPolarHBondContact O-CB 3.28Å; S124-N128 PolarHBondContact O-N 3.12Å; L125-N128 PolarHBondContact O-N 3.33Å; Y126-N128 VanDerWaalsContact C-N 3.33Å; Y126-N128 PolarHBondContact O-N 2.89Å; N128-Y130 PolarHBondContact O-N 2.95Å; N128-S131 WeakPolarHBondContact CA-OG 3.43Å; N128-S131 PolarHBondContact O-N 3.4Å; N128-S131 PolarHBondContact O-OG 3.49Å; N128-S131 VanDerWaalsContact O-OG 3.09Å; N128-S132 WeakPolarHBondContact O-CB 3.48Å; N128-S132 PolarHBondContact O-N 3.37Å; N128-S132 PolarHBondContact O-OG 2.92Å
129	M	96.4	Very high	94.7	Very high	5 Å²	5	18.3 Å²	18.3	3%	0.025	9%	0.089	C	C	.	.	H	α-helix	trans	-57.4	-51	-178.5	-172.2	179.3	79.8	0	0	111.7	L125 Y126 S132 I133 F267 Y270 H271	L125-M129 WeakPolarHBondContact O-CB 3.45Å; L125-M129 PolarHBondContact O-N 3.37Å; Y126-M129 HydrophobicContact CD1-CE 3.96Å; Y126-M129 HydrophobicContact CE1-CE 4.31Å; Y126-M129 PolarHBondContact O-N 3.2Å; M129-S132 PolarHBondContact O-N 2.94Å; M129-I133 HydrophobicContact CG-CD1 4.22Å; M129-I133 VanDerWaalsContact O-CG1 3.31Å; M129-I133 WeakPolarHBondContact O-CG1 3.31Å; M129-I133 PolarHBondContact O-N 3.39Å; M129-F267 HydrophobicContact CG-CD1 4.09Å; M129-F267 HydrophobicContact CG-CE1 3.9Å; M129-Y270 HydrophobicContact CE-CE1 4.03Å; M129-Y270 HydrophobicContact SD-CD1 3.79Å; M129-Y270 HydrophobicContact SD-CE1 3.57Å; M129-Y270 VanDerWaalsContact SD-CE1 3.57Å; M129-H271 VanDerWaalsContact CE-CE1 3.46Å; M129-H271 WeakPolarHBondContact CE-CE1 3.47Å; M129-H271 WeakPolarHBondContact CE-NE2 3.33Å
130	Y	96.8	Very high	94.4	Very high	17 Å²	17	15.3 Å²	15.3	7%	0.067	8%	0.078	C	C	.	.	H	α-helix	trans	-73.8	-40.6	-177.7	-62	-56.4	0	0	0	112.4	Y126 N128 S132 I133 Y134 A212 H271	Y126-Y130 AromaticContact CD1-CE2 3.73Å; Y126-Y130 HydrophobicContact CD1-CE2 3.73Å; Y126-Y130 HydrophobicContact CG-CE2 4.32Å; Y126-Y130 WeakPolarHBondContact O-CD2 3.26Å; Y126-Y130 PolarHBondContact O-N 3.34Å; N128-Y130 PolarHBondContact O-N 2.95Å; Y130-S132 PolarHBondContact O-N 3.46Å; Y130-I133 HydrophobicContact CD1-CD1 4.35Å; Y130-I133 PolarHBondContact O-N 3.26Å; Y130-Y134 WeakPolarHBondContact O-CD2 3.3Å; Y130-Y134 PolarHBondContact O-N 3.5Å; Y130-A212 HydrophobicContact CE1-CB 4.3Å; Y130-A212 WeakPolarHBondContact OH-CB 3.43Å; Y130-H271 AromaticContact CE1-CE1 4Å
131	S	97.9	Very high	94.2	Very high	0 Å²	0	13.9 Å²	13.9	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-59.7	-39.8	174.8	59.9	0	0	0	0	111	S90 V127 N128 Y134 F135	S90-S131 PolarHBondContact OG-OG 2.89Å; V127-S131 WeakPolarHBondContact O-CB 3.41Å; V127-S131 PolarHBondContact O-N 3.49Å; V127-S131 PolarHBondContact O-OG 3.35Å; N128-S131 WeakPolarHBondContact CA-OG 3.43Å; N128-S131 PolarHBondContact O-N 3.4Å; N128-S131 PolarHBondContact O-OG 3.49Å; N128-S131 VanDerWaalsContact O-OG 3.09Å; S131-Y134 PolarHBondContact O-N 3.04Å; S131-F135 WeakPolarHBondContact O-CB 3.42Å; S131-F135 WeakPolarHBondContact O-CD2 3.44Å; S131-F135 WeakPolarHBondContact O-CG 3.17Å; S131-F135 PolarHBondContact O-N 2.98Å
132	S	97.3	Very high	93.8	Very high	0 Å²	0	13.9 Å²	13.9	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-61.2	-48.6	175.1	-61	0	0	0	0	112.5	L87 N128 M129 Y130 Y134 F135 L136	L87-S132 WeakPolarHBondContact CD1-OG 3.28Å; N128-S132 WeakPolarHBondContact O-CB 3.48Å; N128-S132 PolarHBondContact O-N 3.37Å; N128-S132 PolarHBondContact O-OG 2.92Å; M129-S132 PolarHBondContact O-N 2.94Å; Y130-S132 PolarHBondContact O-N 3.46Å; S132-Y134 VanDerWaalsContact C-N 3.34Å; S132-Y134 PolarHBondContact O-N 3.25Å; S132-F135 PolarHBondContact O-N 3.5Å; S132-L136 WeakPolarHBondContact O-CB 3.42Å; S132-L136 VanDerWaalsContact O-CG 3.23Å; S132-L136 WeakPolarHBondContact O-CG 3.38Å; S132-L136 PolarHBondContact O-N 3.43Å
133	I	96.9	Very high	93.5	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-56.4	-47.2	176.1	-72.3	166.9	0	0	0	111.3	M129 Y130 T137 G216 P220 F263 F267	M129-I133 HydrophobicContact CG-CD1 4.22Å; M129-I133 VanDerWaalsContact O-CG1 3.31Å; M129-I133 WeakPolarHBondContact O-CG1 3.31Å; M129-I133 PolarHBondContact O-N 3.39Å; Y130-I133 HydrophobicContact CD1-CD1 4.35Å; Y130-I133 PolarHBondContact O-N 3.26Å; I133-T137 WeakPolarHBondContact O-CB 3.14Å; I133-T137 PolarHBondContact O-N 3.42Å; I133-T137 PolarHBondContact O-OG1 2.92Å; I133-G216 WeakPolarHBondContact CD1-O 3.48Å; I133-G216 WeakPolarHBondContact CG2-O 3.33Å; I133-P220 HydrophobicContact CG2-CB 3.41Å; I133-P220 VanDerWaalsContact CG2-CB 3.41Å; I133-P220 HydrophobicContact CG2-CG 3.53Å; I133-F263 HydrophobicContact CB-CZ 4.4Å; I133-F263 HydrophobicContact CG1-CZ 4.41Å; I133-F263 HydrophobicContact CG2-CE1 4.09Å; I133-F263 HydrophobicContact CG2-CZ 3.83Å; I133-F267 HydrophobicContact CD1-CD1 4.2Å; I133-F267 HydrophobicContact CD1-CD2 4.09Å; I133-F267 HydrophobicContact CD1-CE1 4.46Å; I133-F267 HydrophobicContact CD1-CE2 4.33Å; I133-F267 HydrophobicContact CD1-CG 4.03Å; I133-F267 HydrophobicContact CG1-CD1 4.34Å; I133-F267 HydrophobicContact CG1-CD2 3.57Å; I133-F267 HydrophobicContact CG1-CE1 4.27Å; I133-F267 HydrophobicContact CG1-CE2 3.47Å; I133-F267 VanDerWaalsContact CG1-CE2 3.47Å; I133-F267 HydrophobicContact CG1-CG 4.03Å; I133-F267 HydrophobicContact CG1-CZ 3.85Å
134	Y	97.3	Very high	93	Very high	35 Å²	35	12.7 Å²	12.7	14%	0.137	7%	0.065	C	C	.	.	H	α-helix	trans	-68.9	-42.3	179.8	-78.7	-68.8	0	0	0	112.8	Y130 S131 S132 L136 T137 V138 F172 T173 V215 P220	Y130-Y134 WeakPolarHBondContact O-CD2 3.3Å; Y130-Y134 PolarHBondContact O-N 3.5Å; S131-Y134 PolarHBondContact O-N 3.04Å; S132-Y134 VanDerWaalsContact C-N 3.34Å; S132-Y134 PolarHBondContact O-N 3.25Å; Y134-L136 PolarHBondContact O-N 2.98Å; Y134-T137 PolarHBondContact O-N 2.97Å; Y134-V138 WeakPolarHBondContact O-CG2 3.47Å; Y134-V138 PolarHBondContact O-N 2.96Å; Y134-F172 AromaticContact CE2-CD1 3.97Å; Y134-F172 HydrophobicContact CE2-CD1 3.97Å; Y134-F172 AromaticContact CE2-CE1 3.61Å; Y134-F172 HydrophobicContact CE2-CE1 3.61Å; Y134-F172 AromaticContact CZ-CE1 3.7Å; Y134-F172 WeakPolarHBondContact OH-CE1 3.45Å; Y134-T173 HydrophobicContact CD2-CG2 3.98Å; Y134-T173 HydrophobicContact CE2-CG2 4.4Å; Y134-V215 PolarHBondContact OH-O 3.19Å; Y134-P220 HydrophobicContact CE1-CG 4.14Å
135	F	96.4	Very high	92.3	Very high	2 Å²	2	13.4 Å²	13.4	1%	0.009	7%	0.067	C	C	.	.	H	α-helix	trans	-62.9	-42.2	176.8	-74.2	-48.1	0	0	0	112	F83 N86 L87 S131 S132 T137 L139 C166 I169 W170	F83-F135 HydrophobicContact CD1-CD1 4.19Å; N86-F135 HydrophobicContact CB-CE1 3.89Å; N86-F135 HydrophobicContact CB-CE2 3.93Å; N86-F135 HydrophobicContact CB-CZ 3.55Å; L87-F135 HydrophobicContact CB-CB 4.26Å; L87-F135 HydrophobicContact CB-CD2 4.27Å; L87-F135 HydrophobicContact CB-CG 4.48Å; L87-F135 HydrophobicContact CD1-CB 4.19Å; L87-F135 HydrophobicContact CD1-CD2 4.24Å; S131-F135 WeakPolarHBondContact O-CB 3.42Å; S131-F135 WeakPolarHBondContact O-CD2 3.44Å; S131-F135 WeakPolarHBondContact O-CG 3.17Å; S131-F135 PolarHBondContact O-N 2.98Å; S132-F135 PolarHBondContact O-N 3.5Å; F135-T137 VanDerWaalsContact C-N 3.32Å; F135-T137 PolarHBondContact O-N 3.49Å; F135-L139 WeakPolarHBondContact O-CB 3.43Å; F135-L139 PolarHBondContact O-N 3.48Å; F135-C166 HydrophobicContact CE1-CB 4.04Å; F135-C166 HydrophobicContact CZ-CB 4.43Å; F135-I169 HydrophobicContact CD1-CD1 3.76Å; F135-I169 HydrophobicContact CD1-CG2 4.5Å; F135-I169 HydrophobicContact CE1-CB 4.2Å; F135-I169 HydrophobicContact CE1-CD1 3.72Å; F135-I169 HydrophobicContact CE1-CG2 4.08Å; F135-I169 HydrophobicContact CE2-CG2 4.26Å; F135-I169 HydrophobicContact CZ-CB 4.32Å; F135-I169 HydrophobicContact CZ-CG2 3.93Å; F135-W170 AromaticContact CZ-NE1 3.84Å
136	L	94	Very high	91.5	Very high	0 Å²	0	14 Å²	14	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-62.3	-40.7	173.9	-70.9	173.2	0	0	0	111.6	L87 S132 Y134 L139 S140 T259 I262 F263 F267 L311	L87-L136 HydrophobicContact CD2-CD2 3.97Å; L87-L136 HydrophobicContact CD2-CG 4.31Å; S132-L136 WeakPolarHBondContact O-CB 3.42Å; S132-L136 VanDerWaalsContact O-CG 3.23Å; S132-L136 WeakPolarHBondContact O-CG 3.38Å; S132-L136 PolarHBondContact O-N 3.43Å; Y134-L136 PolarHBondContact O-N 2.98Å; L136-L139 PolarHBondContact O-N 3.2Å; L136-S140 WeakPolarHBondContact O-CB 3.23Å; L136-S140 PolarHBondContact O-N 2.94Å; L136-S140 PolarHBondContact O-OG 2.99Å; L136-T259 HydrophobicContact CB-CG2 4Å; L136-I262 HydrophobicContact CD1-CD1 4.43Å; L136-I262 HydrophobicContact CD1-CG2 3.96Å; L136-F263 HydrophobicContact CB-CE2 4.12Å; L136-F263 HydrophobicContact CD1-CE2 4.11Å; L136-F267 HydrophobicContact CD1-CE2 4.19Å; L136-L311 HydrophobicContact CD2-CD2 3.45Å; L136-L311 VanDerWaalsContact CD2-CD2 3.45Å
137	T	93.8	Very high	90.6	Very high	12 Å²	12	13 Å²	13	7%	0.074	7%	0.072	C	C	.	.	H	α-helix	trans	-63.9	-51.6	178	-58.4	0	0	0	0	111.6	I133 Y134 F135 L139 S140 V141 P220 T223 L224	I133-T137 WeakPolarHBondContact O-CB 3.14Å; I133-T137 PolarHBondContact O-N 3.42Å; I133-T137 PolarHBondContact O-OG1 2.92Å; Y134-T137 PolarHBondContact O-N 2.97Å; F135-T137 VanDerWaalsContact C-N 3.32Å; F135-T137 PolarHBondContact O-N 3.49Å; T137-L139 VanDerWaalsContact C-N 3.31Å; T137-L139 PolarHBondContact O-N 3.35Å; T137-S140 PolarHBondContact O-N 3.41Å; T137-V141 VanDerWaalsContact O-CG2 3.32Å; T137-V141 WeakPolarHBondContact O-CG2 3.27Å; T137-V141 PolarHBondContact O-N 2.84Å; T137-P220 WeakPolarHBondContact OG1-CB 3.31Å; T137-T223 HydrophobicContact CG2-CG2 3.85Å; T137-L224 HydrophobicContact CG2-CD2 4.39Å; T137-L224 HydrophobicContact CG2-CG 4.4Å
138	V	93.1	Very high	89.5	Confident	22 Å²	22	14.5 Å²	14.5	13%	0.133	8%	0.081	C	C	.	.	H	α-helix	trans	-61.5	-41.6	177.9	169.3	0	0	0	0	110.9	F83 Y134 S140 V141 V142 L165 I169	F83-V138 HydrophobicContact CD1-CG1 3.96Å; F83-V138 HydrophobicContact CD2-CG1 4.22Å; F83-V138 HydrophobicContact CE1-CG1 3.54Å; F83-V138 HydrophobicContact CE2-CG1 3.82Å; F83-V138 HydrophobicContact CG-CG1 4.3Å; F83-V138 HydrophobicContact CZ-CG1 3.46Å; F83-V138 VanDerWaalsContact CZ-CG1 3.46Å; Y134-V138 WeakPolarHBondContact O-CG2 3.47Å; Y134-V138 PolarHBondContact O-N 2.96Å; V138-S140 PolarHBondContact O-N 2.95Å; V138-V141 PolarHBondContact O-N 3.16Å; V138-V142 HydrophobicContact CG1-CG2 4.24Å; V138-V142 WeakPolarHBondContact O-CB 3.32Å; V138-V142 VanDerWaalsContact O-CG2 3.31Å; V138-V142 WeakPolarHBondContact O-CG2 3.47Å; V138-V142 PolarHBondContact O-N 3.47Å; V138-L165 HydrophobicContact CB-CD2 4.4Å; V138-L165 HydrophobicContact CG1-CD2 3.53Å; V138-L165 HydrophobicContact CG1-CG 4.5Å; V138-L165 HydrophobicContact CG2-CD2 3.91Å; V138-L165 HydrophobicContact CG2-CG 4.45Å; V138-I169 HydrophobicContact CG2-CD1 4.07Å
139	L	90	Very high	88.2	Confident	2 Å²	2	19 Å²	19	1%	0.01	10%	0.102	C	C	.	.	H	α-helix	trans	-60	-47.1	176.6	179.3	62.9	0	0	0	111.3	V80 M84 F135 L136 T137 V141 V142 R143 T255 L311	V80-L139 HydrophobicContact CB-CD1 4.17Å; V80-L139 HydrophobicContact CG1-CD1 3.53Å; V80-L139 HydrophobicContact CG2-CD1 3.98Å; M84-L139 HydrophobicContact CE-CD1 4.09Å; M84-L139 HydrophobicContact CE-CD2 3.72Å; M84-L139 HydrophobicContact CG-CD2 4.31Å; F135-L139 WeakPolarHBondContact O-CB 3.43Å; F135-L139 PolarHBondContact O-N 3.48Å; L136-L139 PolarHBondContact O-N 3.2Å; T137-L139 VanDerWaalsContact C-N 3.31Å; T137-L139 PolarHBondContact O-N 3.35Å; L139-V141 VanDerWaalsContact C-N 3.34Å; L139-V141 PolarHBondContact O-N 3.33Å; L139-V142 PolarHBondContact O-N 3.18Å; L139-R143 HydrophobicContact CD1-CG 4.48Å; L139-R143 WeakPolarHBondContact O-CB 3.49Å; L139-R143 VanDerWaalsContact O-CG 3.26Å; L139-R143 WeakPolarHBondContact O-CG 3.34Å; L139-R143 PolarHBondContact O-N 3.09Å; L139-T255 HydrophobicContact CD2-CG2 4.38Å; L139-T255 HydrophobicContact CG-CG2 4.23Å; L139-L311 HydrophobicContact CD2-CD2 3.55Å; L139-L311 HydrophobicContact CD2-CG 4.16Å
140	S	87.6	Confident	86.8	Confident	1 Å²	1	22.3 Å²	22.3	1%	0.007	12%	0.124	C	C	.	.	H	α-helix	trans	-61.2	-39.8	175.6	-73.5	0	0	0	0	112.7	L136 T137 V138 R143 F144 Y228	L136-S140 WeakPolarHBondContact O-CB 3.23Å; L136-S140 PolarHBondContact O-N 2.94Å; L136-S140 PolarHBondContact O-OG 2.99Å; T137-S140 PolarHBondContact O-N 3.41Å; V138-S140 PolarHBondContact O-N 2.95Å; S140-R143 PolarHBondContact O-N 3.32Å; S140-F144 WeakPolarHBondContact O-CB 3.47Å; S140-F144 PolarHBondContact O-N 2.75Å; S140-Y228 PolarHBondContact OG-OH 3.04Å
141	V	88.3	Confident	85	Confident	40 Å²	40	30.8 Å²	30.8	24%	0.242	16%	0.161	C	C	.	.	H	α-helix	trans	-64.5	-46.1	174.9	171.9	0	0	0	0	111.2	T137 V138 L139 R143 F144 L145 T223	T137-V141 VanDerWaalsContact O-CG2 3.32Å; T137-V141 WeakPolarHBondContact O-CG2 3.27Å; T137-V141 PolarHBondContact O-N 2.84Å; V138-V141 PolarHBondContact O-N 3.16Å; L139-V141 VanDerWaalsContact C-N 3.34Å; L139-V141 PolarHBondContact O-N 3.33Å; V141-R143 VanDerWaalsContact C-N 3.28Å; V141-R143 PolarHBondContact O-N 2.83Å; V141-F144 WeakPolarHBondContact O-CB 3.37Å; V141-F144 PolarHBondContact O-N 3.12Å; V141-L145 HydrophobicContact CG1-CD1 3.98Å; V141-L145 HydrophobicContact CG1-CG 4.37Å; V141-L145 WeakPolarHBondContact O-CG 3.23Å; V141-L145 PolarHBondContact O-N 3.45Å; V141-T223 HydrophobicContact CG2-CG2 4.06Å
142	V	86.3	Confident	82.9	Confident	9 Å²	9	41.2 Å²	41.2	6%	0.055	20%	0.201	C	C	.	.	H	α-helix	trans	-61.8	-39.4	177.7	168.8	0	0	0	0	110.8	V80 F83 V138 L139 L145 A146	V80-V142 HydrophobicContact CG2-CG1 3.89Å; F83-V142 HydrophobicContact CE2-CG2 3.97Å; V138-V142 HydrophobicContact CG1-CG2 4.24Å; V138-V142 WeakPolarHBondContact O-CB 3.32Å; V138-V142 VanDerWaalsContact O-CG2 3.31Å; V138-V142 WeakPolarHBondContact O-CG2 3.47Å; V138-V142 PolarHBondContact O-N 3.47Å; L139-V142 PolarHBondContact O-N 3.18Å; V142-L145 PolarHBondContact O-N 2.83Å; V142-A146 WeakPolarHBondContact O-CB 3.29Å; V142-A146 PolarHBondContact O-N 2.96Å
143	R	82.1	Confident	81	Confident	15 Å²	15	44.7 Å²	44.7	6%	0.057	22%	0.219	C	C	.	.	H	α-helix	trans	-65.6	-42	174.3	-70	-59.5	-173.5	-172.1	4.5	112.7	L139 S140 V141 T147 T255 A315 E317	L139-R143 HydrophobicContact CD1-CG 4.48Å; L139-R143 WeakPolarHBondContact O-CB 3.49Å; L139-R143 VanDerWaalsContact O-CG 3.26Å; L139-R143 WeakPolarHBondContact O-CG 3.34Å; L139-R143 PolarHBondContact O-N 3.09Å; S140-R143 PolarHBondContact O-N 3.32Å; V141-R143 VanDerWaalsContact C-N 3.28Å; V141-R143 PolarHBondContact O-N 2.83Å; R143-T147 WeakPolarHBondContact O-CB 3.46Å; R143-T147 PolarHBondContact O-N 3.05Å; R143-T147 VanDerWaalsContact O-N 3.12Å; R143-T147 PolarHBondContact O-OG1 2.94Å; R143-T255 HydrophobicContact CG-CG2 4.07Å; R143-A315 PolarHBondContact NH2-O 3.18Å; R143-E317 IonicContact CZ-OE1 2.75Å; R143-E317 IonicContact NH1-OE1 3.12Å; R143-E317 PolarHBondContact NH1-OE1 3.11Å; R143-E317 IonicContact NH2-OE1 2.79Å; R143-E317 PolarHBondContact NH2-OE1 2.96Å
144	F	81.3	Confident	79	Confident	22 Å²	22	52 Å²	52	10%	0.096	26%	0.257	C	S	.	.	H	α-helix	trans	-56.6	-53.4	172.5	164.8	-116.3	0	0	0	110.9	S140 V141 A146 T147 V148 L230 I231	S140-F144 WeakPolarHBondContact O-CB 3.47Å; S140-F144 PolarHBondContact O-N 2.75Å; V141-F144 WeakPolarHBondContact O-CB 3.37Å; V141-F144 PolarHBondContact O-N 3.12Å; F144-A146 PolarHBondContact O-N 3.08Å; F144-T147 PolarHBondContact O-N 2.9Å; F144-V148 HydrophobicContact CD2-CB 4.23Å; F144-V148 HydrophobicContact CD2-CG2 3.59Å; F144-V148 HydrophobicContact CE2-CB 3.88Å; F144-V148 HydrophobicContact CE2-CG1 4.19Å; F144-V148 HydrophobicContact CE2-CG2 3.46Å; F144-V148 VanDerWaalsContact CE2-CG2 3.46Å; F144-V148 HydrophobicContact CZ-CB 4.41Å; F144-V148 HydrophobicContact CZ-CG1 4.49Å; F144-V148 HydrophobicContact CZ-CG2 4.43Å; F144-V148 PolarHBondContact O-N 2.93Å; F144-L230 HydrophobicContact CD2-CB 4.22Å; F144-L230 HydrophobicContact CE1-CD1 4.3Å; F144-L230 HydrophobicContact CE2-CB 3.38Å; F144-L230 HydrophobicContact CE2-CD1 4.22Å; F144-L230 HydrophobicContact CE2-CG 4.45Å; F144-L230 HydrophobicContact CZ-CB 3.76Å; F144-L230 HydrophobicContact CZ-CD1 3.69Å; F144-L230 HydrophobicContact CZ-CG 4.37Å; F144-I231 HydrophobicContact CB-CD1 3.81Å; F144-I231 HydrophobicContact CB-CG1 3.8Å; F144-I231 HydrophobicContact CD2-CD1 4.4Å; F144-I231 HydrophobicContact CD2-CG1 3.46Å; F144-I231 VanDerWaalsContact CD2-CG1 3.46Å; F144-I231 HydrophobicContact CE2-CG1 4.48Å; F144-I231 HydrophobicContact CG-CG1 4.08Å
145	L	81.1	Confident	76.9	Confident	34 Å²	34	57.2 Å²	57.2	18%	0.178	28%	0.282	C	S	.	.	H	α-helix	trans	-61.3	-43	-177.9	-68.1	173.3	0	0	0	112.1	V141 V142 T147 H149 L153 V156	V141-L145 HydrophobicContact CG1-CD1 3.98Å; V141-L145 HydrophobicContact CG1-CG 4.37Å; V141-L145 WeakPolarHBondContact O-CG 3.23Å; V141-L145 PolarHBondContact O-N 3.45Å; V142-L145 PolarHBondContact O-N 2.83Å; L145-T147 PolarHBondContact O-N 3.22Å; L145-H149 CarbonylContact O-C 3.36Å; L145-H149 WeakPolarHBondContact O-CA 3.23Å; L145-H149 PolarHBondContact O-N 3.32Å; L145-L153 HydrophobicContact CD1-CD2 4.29Å; L145-V156 HydrophobicContact CD1-CG1 4.22Å
146	A	77.8	Confident	75	Confident	36 Å²	36	60.4 Å²	60.4	30%	0.298	30%	0.302	S	S	.	.	H	α-helix	trans	-64.5	-24.9	176.8	0	0	0	0	0	113.4	V142 F144	V142-A146 WeakPolarHBondContact O-CB 3.29Å; V142-A146 PolarHBondContact O-N 2.96Å; F144-A146 PolarHBondContact O-N 3.08Å
147	T	73.3	Confident	73.9	Confident	9 Å²	9	62.7 Å²	62.7	6%	0.055	32%	0.316	C	S	.	.	H	α-helix	trans	-88.1	-42.7	-179.8	-56.6	0	0	0	0	111.8	R143 F144 L145 L235 H249 A252	R143-T147 WeakPolarHBondContact O-CB 3.46Å; R143-T147 PolarHBondContact O-N 3.05Å; R143-T147 VanDerWaalsContact O-N 3.12Å; R143-T147 PolarHBondContact O-OG1 2.94Å; F144-T147 PolarHBondContact O-N 2.9Å; L145-T147 PolarHBondContact O-N 3.22Å; T147-L235 HydrophobicContact CG2-CD2 4.2Å; T147-H249 VanDerWaalsContact CG2-CD2 3.5Å; T147-H249 WeakPolarHBondContact CG2-CD2 3.28Å; T147-A252 WeakPolarHBondContact OG1-CB 3.34Å
148	V	74.1	Confident	73.4	Confident	41 Å²	41	64.3 Å²	64.3	25%	0.248	33%	0.327	C	S	.	.	H	α-helix	trans	-96.2	-29	-170	-177.7	0	0	0	0	112.9	F144 A234	F144-V148 HydrophobicContact CD2-CB 4.23Å; F144-V148 HydrophobicContact CD2-CG2 3.59Å; F144-V148 HydrophobicContact CE2-CB 3.88Å; F144-V148 HydrophobicContact CE2-CG1 4.19Å; F144-V148 HydrophobicContact CE2-CG2 3.46Å; F144-V148 VanDerWaalsContact CE2-CG2 3.46Å; F144-V148 HydrophobicContact CZ-CB 4.41Å; F144-V148 HydrophobicContact CZ-CG1 4.49Å; F144-V148 HydrophobicContact CZ-CG2 4.43Å; F144-V148 PolarHBondContact O-N 2.93Å; V148-A234 HydrophobicContact CB-CB 4.46Å; V148-A234 HydrophobicContact CG1-CB 4.25Å; V148-A234 HydrophobicContact CG2-CB 3.49Å; V148-A234 VanDerWaalsContact CG2-CB 3.49Å
149	H	70.9	Confident	73.2	Confident	97 Å²	97	66.6 Å²	66.6	45%	0.449	34%	0.338	S	S	.	.			trans	-134.8	60.9	-176.6	-63.3	-49.8	0	0	0	112.9	L145 F151 R152	L145-H149 CarbonylContact O-C 3.36Å; L145-H149 WeakPolarHBondContact O-CA 3.23Å; L145-H149 PolarHBondContact O-N 3.32Å; H149-F151 PolarHBondContact O-N 3.13Å; H149-F151 VanDerWaalsContact O-N 3.09Å; H149-R152 HydrophobicContact CB-CB 4.46Å; H149-R152 PolarHBondContact O-N 3.46Å
150	P	66.4	Low	73.2	Confident	74 Å²	74	75.9 Å²	75.9	48%	0.481	37%	0.373	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.5	-27.1	-172.4	22.2	-32.9	0	0	0	114.7
151	F	58.5	Low	73.3	Confident	196 Å²	196	77.2 Å²	77.2	86%	0.86	38%	0.383	S	S	*	.	T	Hydrogen-bonded Turn	trans	-99.1	-16.9	-175.3	-61.9	-73.6	0	0	0	115	H149	H149-F151 PolarHBondContact O-N 3.13Å; H149-F151 VanDerWaalsContact O-N 3.09Å
152	R	54.9	Low	73.6	Confident	219 Å²	219	75.4 Å²	75.4	83%	0.826	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.2	-9	-169.2	-82	-158.5	177.9	-166.2	1	115.3	H149	H149-R152 HydrophobicContact CB-CB 4.46Å; H149-R152 PolarHBondContact O-N 3.46Å
153	L	56.9	Low	74	Confident	73 Å²	73	81 Å²	81	38%	0.382	39%	0.392	S	S	.	.			trans	-150.1	52.7	-166.1	-131.6	65.2	0	0	0	116.6	L145 H155 V156 T157	L145-L153 HydrophobicContact CD1-CD2 4.29Å; L153-H155 PolarHBondContact O-N 3.44Å; L153-H155 VanDerWaalsContact O-N 3.08Å; L153-V156 HydrophobicContact CD1-CG2 4.36Å; L153-V156 HydrophobicContact CD2-CB 3.53Å; L153-V156 HydrophobicContact CD2-CG1 4.12Å; L153-V156 HydrophobicContact CD2-CG2 3.4Å; L153-V156 HydrophobicContact CG-CB 3.73Å; L153-V156 HydrophobicContact CG-CG2 3.61Å; L153-V156 PolarHBondContact O-N 3.36Å; L153-T157 PolarHBondContact O-N 3.44Å; L153-T157 PolarHBondContact O-OG1 3.49Å; L153-T157 VanDerWaalsContact O-OG1 3.12Å
154	L	55.7	Low	74.6	Confident	152 Å²	152	85 Å²	85	80%	0.796	41%	0.413	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.9	-29.6	169.4	-127.7	84.9	0	0	0	112.9	T157 S158	L154-T157 PolarHBondContact O-OG1 2.71Å; L154-S158 PolarHBondContact O-N 3.25Å
155	H	52.8	Low	75.3	Confident	146 Å²	146	86.9 Å²	86.9	68%	0.676	42%	0.424	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.9	-40	-175.3	-166.8	58.8	0	0	0	114.3	L153 T157 S158 S161	L153-H155 PolarHBondContact O-N 3.44Å; L153-H155 VanDerWaalsContact O-N 3.08Å; H155-T157 VanDerWaalsContact C-N 3.33Å; H155-S158 VanDerWaalsContact O-CB 3.29Å; H155-S158 WeakPolarHBondContact O-CB 3.21Å; H155-S158 PolarHBondContact O-N 2.95Å; H155-S161 PolarHBondContact O-OG 3.12Å
156	V	56.4	Low	76.1	Confident	68 Å²	68	85.3 Å²	85.3	41%	0.412	42%	0.416	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.6	-26.9	177.8	171.6	0	0	0	0	111.5	L145 L153 S158	L145-V156 HydrophobicContact CD1-CG1 4.22Å; L153-V156 HydrophobicContact CD1-CG2 4.36Å; L153-V156 HydrophobicContact CD2-CB 3.53Å; L153-V156 HydrophobicContact CD2-CG1 4.12Å; L153-V156 HydrophobicContact CD2-CG2 3.4Å; L153-V156 HydrophobicContact CG-CB 3.73Å; L153-V156 HydrophobicContact CG-CG2 3.61Å; L153-V156 PolarHBondContact O-N 3.36Å; V156-S158 VanDerWaalsContact C-N 3.3Å
157	T	70.1	Confident	77.1	Confident	49 Å²	49	85 Å²	85	30%	0.301	42%	0.416	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.8	2.9	174.8	57.3	0	0	0	0	113.8	S79 L153 L154 H155	S79-T157 WeakPolarHBondContact CB-O 3.39Å; S79-T157 PolarHBondContact OG-O 2.97Å; L153-T157 PolarHBondContact O-N 3.44Å; L153-T157 PolarHBondContact O-OG1 3.49Å; L153-T157 VanDerWaalsContact O-OG1 3.12Å; L154-T157 PolarHBondContact O-OG1 2.71Å; H155-T157 VanDerWaalsContact C-N 3.33Å
158	S	84.6	Confident	78.2	Confident	45 Å²	45	89.2 Å²	89.2	32%	0.315	44%	0.438	S	S	.	.			trans	-67.2	146.5	179.2	178.7	0	0	0	0	112.1	L154 H155 V156 R160 S161 A162	L154-S158 PolarHBondContact O-N 3.25Å; H155-S158 VanDerWaalsContact O-CB 3.29Å; H155-S158 WeakPolarHBondContact O-CB 3.21Å; H155-S158 PolarHBondContact O-N 2.95Å; V156-S158 VanDerWaalsContact C-N 3.3Å; S158-R160 VanDerWaalsContact C-N 3.28Å; S158-R160 PolarHBondContact O-N 3.47Å; S158-R160 PolarHBondContact OG-N 2.89Å; S158-S161 PolarHBondContact O-N 3.07Å; S158-A162 PolarHBondContact O-N 3.48Å
159	I	88.8	Confident	79.3	Confident	71 Å²	71	87.8 Å²	87.8	36%	0.364	43%	0.428	S	S	.	.	H	α-helix	trans	-60.7	-38.9	176.3	-63.2	174.6	0	0	0	111	S77 V82 A162 W163	S77-I159 WeakPolarHBondContact O-CD1 3.34Å; V82-I159 HydrophobicContact CG2-CG2 4.1Å; I159-A162 WeakPolarHBondContact O-CB 3.47Å; I159-A162 PolarHBondContact O-N 3.24Å; I159-W163 VanDerWaalsContact O-CD1 3.32Å; I159-W163 PolarHBondContact O-N 2.7Å
160	R	90.3	Very high	80.6	Confident	197 Å²	197	85.4 Å²	85.4	74%	0.743	42%	0.416	S	S	*	.	H	α-helix	trans	-64.2	-46.6	179.4	-173.9	176.8	-179.9	166.9	0.3	111.1	S158 A162 W163 I164	S158-R160 VanDerWaalsContact C-N 3.28Å; S158-R160 PolarHBondContact O-N 3.47Å; S158-R160 PolarHBondContact OG-N 2.89Å; R160-A162 VanDerWaalsContact C-N 3.27Å; R160-A162 PolarHBondContact O-N 3.2Å; R160-W163 PolarHBondContact O-N 3.48Å; R160-I164 HydrophobicContact CG-CD1 4.18Å; R160-I164 WeakPolarHBondContact O-CG1 3.36Å; R160-I164 PolarHBondContact O-N 3.4Å
161	S	90	Very high	82.2	Confident	29 Å²	29	87.8 Å²	87.8	20%	0.203	42%	0.423	C	S	.	.	H	α-helix	trans	-60.7	-38.2	176.1	-50.8	0	0	0	0	111.4	H155 S158 I164 L165	H155-S161 PolarHBondContact O-OG 3.12Å; S158-S161 PolarHBondContact O-N 3.07Å; S161-I164 PolarHBondContact O-N 2.56Å; S161-L165 WeakPolarHBondContact O-CB 3.22Å; S161-L165 PolarHBondContact O-N 3.3Å
162	A	92.7	Very high	83.9	Confident	1 Å²	1	82.8 Å²	82.8	1%	0.008	40%	0.401	C	S	.	.	H	α-helix	trans	-63.1	-44.2	176.3	0	0	0	0	0	112.7	V82 F83 S158 I159 R160 L165 C166	V82-A162 HydrophobicContact CB-CB 4.01Å; V82-A162 HydrophobicContact CG1-CB 4.16Å; V82-A162 HydrophobicContact CG2-CB 4.35Å; F83-A162 HydrophobicContact CE1-CB 4.18Å; F83-A162 HydrophobicContact CE2-CB 3.86Å; F83-A162 HydrophobicContact CZ-CB 3.63Å; S158-A162 PolarHBondContact O-N 3.48Å; I159-A162 WeakPolarHBondContact O-CB 3.47Å; I159-A162 PolarHBondContact O-N 3.24Å; R160-A162 VanDerWaalsContact C-N 3.27Å; R160-A162 PolarHBondContact O-N 3.2Å; A162-L165 PolarHBondContact O-N 2.78Å; A162-C166 PolarHBondContact O-N 3.42Å; A162-C166 PolarHBondContact O-SG 3.48Å
163	W	95.5	Very high	85.9	Confident	127 Å²	127	72.4 Å²	72.4	48%	0.481	36%	0.362	S	S	.	.	H	α-helix	trans	-63.5	-42.7	175.3	-81.3	115.1	0	0	0	112.8	V82 I159 R160 L165 C166 G167	V82-W163 HydrophobicContact CG1-CD2 3.58Å; V82-W163 HydrophobicContact CG1-CE3 3.9Å; V82-W163 HydrophobicContact CG1-CG 3.97Å; V82-W163 HydrophobicContact CG1-CH2 4.33Å; V82-W163 HydrophobicContact CG1-CZ2 4.04Å; V82-W163 HydrophobicContact CG1-CZ3 4.26Å; I159-W163 VanDerWaalsContact O-CD1 3.32Å; I159-W163 PolarHBondContact O-N 2.7Å; R160-W163 PolarHBondContact O-N 3.48Å; W163-L165 VanDerWaalsContact C-N 3.34Å; W163-L165 PolarHBondContact O-N 3.2Å; W163-C166 PolarHBondContact O-N 3.48Å; W163-G167 PolarHBondContact O-N 2.79Å
164	I	95.4	Very high	87.7	Confident	98 Å²	98	72.8 Å²	72.8	50%	0.503	36%	0.363	S	S	.	.	H	α-helix	trans	-59.3	-48.1	175.6	-67.2	166.9	0	0	0	110	R160 S161 C166 G167 I168	R160-I164 HydrophobicContact CG-CD1 4.18Å; R160-I164 WeakPolarHBondContact O-CG1 3.36Å; R160-I164 PolarHBondContact O-N 3.4Å; S161-I164 PolarHBondContact O-N 2.56Å; I164-C166 PolarHBondContact O-N 2.75Å; I164-G167 PolarHBondContact O-N 3.39Å; I164-G167 VanDerWaalsContact O-N 3.15Å; I164-I168 HydrophobicContact CG2-CD1 4.06Å; I164-I168 WeakPolarHBondContact O-CG1 3.17Å; I164-I168 PolarHBondContact O-N 2.96Å
165	L	95.4	Very high	89.5	Confident	62 Å²	62	68.4 Å²	68.4	33%	0.325	35%	0.348	S	S	.	.	H	α-helix	trans	-64.9	-37.9	179.9	-174.8	56.4	0	0	0	112.3	F83 V138 S161 A162 W163 G167 I168 I169	F83-L165 HydrophobicContact CE1-CB 4.22Å; F83-L165 HydrophobicContact CE1-CD2 4.06Å; F83-L165 HydrophobicContact CE1-CG 4.23Å; F83-L165 HydrophobicContact CZ-CB 4.5Å; F83-L165 HydrophobicContact CZ-CD2 4Å; V138-L165 HydrophobicContact CB-CD2 4.4Å; V138-L165 HydrophobicContact CG1-CD2 3.53Å; V138-L165 HydrophobicContact CG1-CG 4.5Å; V138-L165 HydrophobicContact CG2-CD2 3.91Å; V138-L165 HydrophobicContact CG2-CG 4.45Å; S161-L165 WeakPolarHBondContact O-CB 3.22Å; S161-L165 PolarHBondContact O-N 3.3Å; A162-L165 PolarHBondContact O-N 2.78Å; W163-L165 VanDerWaalsContact C-N 3.34Å; W163-L165 PolarHBondContact O-N 3.2Å; L165-G167 VanDerWaalsContact C-N 3.34Å; L165-I168 PolarHBondContact O-N 2.92Å; L165-I169 HydrophobicContact CG-CD1 4.29Å; L165-I169 WeakPolarHBondContact O-CG1 3.27Å; L165-I169 PolarHBondContact O-N 3.35Å
166	C	97.6	Very high	91.3	Very high	1 Å²	1	64.1 Å²	64.1	1%	0.007	34%	0.335	C	S	.	.	H	α-helix	trans	-60.3	-44.9	171.6	-66.6	0	0	0	0	111.4	F83 F135 A162 W163 I164 I168 I169 W170	F83-C166 WeakPolarHBondContact CD1-SG 3.38Å; F135-C166 HydrophobicContact CE1-CB 4.04Å; F135-C166 HydrophobicContact CZ-CB 4.43Å; A162-C166 PolarHBondContact O-N 3.42Å; A162-C166 PolarHBondContact O-SG 3.48Å; W163-C166 PolarHBondContact O-N 3.48Å; I164-C166 PolarHBondContact O-N 2.75Å; C166-I168 VanDerWaalsContact C-N 3.33Å; C166-I168 PolarHBondContact O-N 2.87Å; C166-I169 PolarHBondContact O-N 3.09Å; C166-W170 PolarHBondContact O-N 3.48Å
167	G	98	Very high	92.8	Very high	30 Å²	30	61 Å²	61	31%	0.309	32%	0.316	S	S	.	.	H	α-helix	trans	-58.5	-43.2	175.5	0	0	0	0	0	112.6	W163 I164 L165 W170 I171	W163-G167 PolarHBondContact O-N 2.79Å; I164-G167 PolarHBondContact O-N 3.39Å; I164-G167 VanDerWaalsContact O-N 3.15Å; L165-G167 VanDerWaalsContact C-N 3.34Å; G167-W170 PolarHBondContact O-N 3.34Å; G167-I171 WeakPolarHBondContact O-CB 3.42Å; G167-I171 VanDerWaalsContact O-CG1 3.29Å; G167-I171 WeakPolarHBondContact O-CG1 3.38Å; G167-I171 PolarHBondContact O-N 2.88Å
168	I	97.7	Very high	93.7	Very high	98 Å²	98	62.4 Å²	62.4	50%	0.503	32%	0.324	S	S	.	.	H	α-helix	trans	-61	-46.8	175.2	-67	167.8	0	0	0	110.8	I164 L165 C166 W170 I171 F172	I164-I168 HydrophobicContact CG2-CD1 4.06Å; I164-I168 WeakPolarHBondContact O-CG1 3.17Å; I164-I168 PolarHBondContact O-N 2.96Å; L165-I168 PolarHBondContact O-N 2.92Å; C166-I168 VanDerWaalsContact C-N 3.33Å; C166-I168 PolarHBondContact O-N 2.87Å; I168-W170 PolarHBondContact O-N 2.84Å; I168-I171 PolarHBondContact O-N 2.86Å; I168-F172 WeakPolarHBondContact O-CB 3.2Å; I168-F172 PolarHBondContact O-N 3.35Å
169	I	97.8	Very high	93.6	Very high	10 Å²	10	64.2 Å²	64.2	5%	0.051	33%	0.329	C	S	.	.	H	α-helix	trans	-60.6	-45.5	178.5	-69	165.7	0	0	0	110.7	F135 V138 L165 C166 F172 T173	F135-I169 HydrophobicContact CD1-CD1 3.76Å; F135-I169 HydrophobicContact CD1-CG2 4.5Å; F135-I169 HydrophobicContact CE1-CB 4.2Å; F135-I169 HydrophobicContact CE1-CD1 3.72Å; F135-I169 HydrophobicContact CE1-CG2 4.08Å; F135-I169 HydrophobicContact CE2-CG2 4.26Å; F135-I169 HydrophobicContact CZ-CB 4.32Å; F135-I169 HydrophobicContact CZ-CG2 3.93Å; V138-I169 HydrophobicContact CG2-CD1 4.07Å; L165-I169 HydrophobicContact CG-CD1 4.29Å; L165-I169 WeakPolarHBondContact O-CG1 3.27Å; L165-I169 PolarHBondContact O-N 3.35Å; C166-I169 PolarHBondContact O-N 3.09Å; I169-F172 PolarHBondContact O-N 3.47Å; I169-T173 HydrophobicContact CG2-CG2 4.28Å; I169-T173 WeakPolarHBondContact O-CB 3.37Å; I169-T173 VanDerWaalsContact O-CG2 3.28Å; I169-T173 WeakPolarHBondContact O-CG2 3.29Å; I169-T173 PolarHBondContact O-N 2.67Å; I169-T173 PolarHBondContact O-OG1 2.9Å
170	W	98.3	Very high	93.4	Very high	48 Å²	48	61.8 Å²	61.8	18%	0.182	32%	0.316	C	S	.	.	H	α-helix	trans	-59.6	-54.2	177.2	-83.3	115.4	0	0	0	111.7	N86 L93 V127 F135 C166 G167 I168 F172 T173 M174	N86-W170 PolarHBondContact OD1-NE1 3.49Å; L93-W170 HydrophobicContact CD1-CH2 4.2Å; V127-W170 HydrophobicContact CG1-CE3 4.41Å; V127-W170 HydrophobicContact CG1-CZ3 3.96Å; F135-W170 AromaticContact CZ-NE1 3.84Å; C166-W170 PolarHBondContact O-N 3.48Å; G167-W170 PolarHBondContact O-N 3.34Å; I168-W170 PolarHBondContact O-N 2.84Å; W170-F172 VanDerWaalsContact C-N 3.31Å; W170-F172 PolarHBondContact O-N 3.48Å; W170-T173 PolarHBondContact O-N 3.21Å; W170-T173 PolarHBondContact O-OG1 3.39Å; W170-M174 HydrophobicContact CE3-CG 4.34Å; W170-M174 HydrophobicContact CE3-SD 4.16Å; W170-M174 WeakPolarHBondContact O-CB 3.42Å; W170-M174 WeakPolarHBondContact O-CG 3.19Å; W170-M174 PolarHBondContact O-N 2.98Å
171	I	98.1	Very high	93.2	Very high	124 Å²	124	54.8 Å²	54.8	64%	0.636	29%	0.294	S	S	*	.	H	α-helix	trans	-58.2	-46.7	179.8	-67.8	167.3	0	0	0	110.3	G167 I168 A175	G167-I171 WeakPolarHBondContact O-CB 3.42Å; G167-I171 VanDerWaalsContact O-CG1 3.29Å; G167-I171 WeakPolarHBondContact O-CG1 3.38Å; G167-I171 PolarHBondContact O-N 2.88Å; I168-I171 PolarHBondContact O-N 2.86Å; I171-A175 WeakPolarHBondContact O-CB 3.23Å; I171-A175 PolarHBondContact O-N 3.38Å
172	F	96.1	Very high	92.8	Very high	91 Å²	91	58.3 Å²	58.3	40%	0.399	31%	0.31	S	S	.	.	H	α-helix	trans	-61.8	-48.6	-179.2	176.3	-102.6	0	0	0	112.6	Y134 I168 I169 W170 S176 V215	Y134-F172 AromaticContact CE2-CD1 3.97Å; Y134-F172 HydrophobicContact CE2-CD1 3.97Å; Y134-F172 AromaticContact CE2-CE1 3.61Å; Y134-F172 HydrophobicContact CE2-CE1 3.61Å; Y134-F172 AromaticContact CZ-CE1 3.7Å; Y134-F172 WeakPolarHBondContact OH-CE1 3.45Å; I168-F172 WeakPolarHBondContact O-CB 3.2Å; I168-F172 PolarHBondContact O-N 3.35Å; I169-F172 PolarHBondContact O-N 3.47Å; W170-F172 VanDerWaalsContact C-N 3.31Å; W170-F172 PolarHBondContact O-N 3.48Å; F172-S176 VanDerWaalsContact O-CB 3.29Å; F172-S176 WeakPolarHBondContact O-CB 3.37Å; F172-S176 PolarHBondContact O-N 3.42Å; F172-S176 PolarHBondContact O-OG 2.83Å; F172-V215 HydrophobicContact CE1-CG1 4.47Å; F172-V215 HydrophobicContact CZ-CG1 3.83Å
173	T	95.6	Very high	92.1	Very high	0 Å²	0	60.4 Å²	60.4	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-70.9	-37.1	-178	53.9	0	0	0	0	112.4	Y134 I169 W170 S176 S177	Y134-T173 HydrophobicContact CD2-CG2 3.98Å; Y134-T173 HydrophobicContact CE2-CG2 4.4Å; I169-T173 HydrophobicContact CG2-CG2 4.28Å; I169-T173 WeakPolarHBondContact O-CB 3.37Å; I169-T173 VanDerWaalsContact O-CG2 3.28Å; I169-T173 WeakPolarHBondContact O-CG2 3.29Å; I169-T173 PolarHBondContact O-N 2.67Å; I169-T173 PolarHBondContact O-OG1 2.9Å; W170-T173 PolarHBondContact O-N 3.21Å; W170-T173 PolarHBondContact O-OG1 3.39Å; T173-S176 WeakPolarHBondContact CA-OG 3.47Å; T173-S176 PolarHBondContact O-OG 3.24Å; T173-S177 VanDerWaalsContact O-CB 3.24Å; T173-S177 WeakPolarHBondContact O-CB 3.36Å; T173-S177 PolarHBondContact O-N 2.93Å; T173-S177 PolarHBondContact O-OG 3.44Å
174	M	95.4	Very high	91.4	Very high	82 Å²	82	55.1 Å²	55.1	40%	0.404	31%	0.306	S	S	.	.	H	α-helix	trans	-67.5	-46	174.6	-73.3	179.8	72.2	0	0	112.2	Y123 V127 W170 S177 V178	Y123-M174 VanDerWaalsContact OH-CA 3.3Å; Y123-M174 WeakPolarHBondContact OH-CA 3.3Å; Y123-M174 WeakPolarHBondContact OH-CB 3.43Å; Y123-M174 WeakPolarHBondContact OH-CG 3.32Å; Y123-M174 PolarHBondContact OH-O 3.34Å; V127-M174 HydrophobicContact CG1-CG 4.1Å; V127-M174 HydrophobicContact CG2-CG 4.48Å; W170-M174 HydrophobicContact CE3-CG 4.34Å; W170-M174 HydrophobicContact CE3-SD 4.16Å; W170-M174 WeakPolarHBondContact O-CB 3.42Å; W170-M174 WeakPolarHBondContact O-CG 3.19Å; W170-M174 PolarHBondContact O-N 2.98Å; M174-S177 PolarHBondContact O-N 3.18Å; M174-V178 PolarHBondContact O-N 2.74Å
175	A	93.3	Very high	90.9	Very high	60 Å²	60	51.9 Å²	51.9	50%	0.496	29%	0.292	S	S	.	.	H	α-helix	trans	-67.3	-44.4	-179.9	0	0	0	0	0	111.7	I171 S177 V178	I171-A175 WeakPolarHBondContact O-CB 3.23Å; I171-A175 PolarHBondContact O-N 3.38Å; A175-S177 PolarHBondContact O-N 2.93Å; A175-V178 WeakPolarHBondContact O-CB 3.47Å; A175-V178 WeakPolarHBondContact O-CG1 3.05Å; A175-V178 PolarHBondContact O-N 3.36Å
176	S	89.4	Confident	90.4	Very high	55 Å²	55	53.2 Å²	53.2	39%	0.385	30%	0.297	S	S	.	.	H	α-helix	trans	-65.1	-27.7	177.6	55.5	0	0	0	0	113.2	F172 T173	F172-S176 VanDerWaalsContact O-CB 3.29Å; F172-S176 WeakPolarHBondContact O-CB 3.37Å; F172-S176 PolarHBondContact O-N 3.42Å; F172-S176 PolarHBondContact O-OG 2.83Å; T173-S176 WeakPolarHBondContact CA-OG 3.47Å; T173-S176 PolarHBondContact O-OG 3.24Å
177	S	88.7	Confident	89.7	Confident	3 Å²	3	61 Å²	61	2%	0.021	33%	0.333	C	S	.	.	H	α-helix	trans	-88	-7.1	178.5	-58	0	0	0	0	113.8	Y123 T173 M174 A175 M179 L180	Y123-S177 WeakPolarHBondContact CD2-O 3.29Å; T173-S177 VanDerWaalsContact O-CB 3.24Å; T173-S177 WeakPolarHBondContact O-CB 3.36Å; T173-S177 PolarHBondContact O-N 2.93Å; T173-S177 PolarHBondContact O-OG 3.44Å; M174-S177 PolarHBondContact O-N 3.18Å; A175-S177 PolarHBondContact O-N 2.93Å; S177-M179 PolarHBondContact O-N 3.36Å; S177-M179 VanDerWaalsContact O-N 3.12Å; S177-L180 VanDerWaalsContact O-CB 3.27Å; S177-L180 WeakPolarHBondContact O-CB 3.41Å; S177-L180 PolarHBondContact O-N 2.89Å
178	V	88.4	Confident	88.8	Confident	78 Å²	78	66 Å²	66	47%	0.473	35%	0.346	S	S	.	.	G	3₁₀ helix	trans	-57.6	-33.6	-171.6	78	0	0	0	0	113	M174 A175 L180 L181	M174-V178 PolarHBondContact O-N 2.74Å; A175-V178 WeakPolarHBondContact O-CB 3.47Å; A175-V178 WeakPolarHBondContact O-CG1 3.05Å; A175-V178 PolarHBondContact O-N 3.36Å; V178-L180 PolarHBondContact O-N 3.37Å; V178-L180 VanDerWaalsContact O-N 3.12Å; V178-L181 HydrophobicContact CG2-CD1 4.23Å; V178-L181 VanDerWaalsContact O-CB 3.3Å; V178-L181 WeakPolarHBondContact O-CB 3.43Å; V178-L181 PolarHBondContact O-N 3.47Å
179	M	84.2	Confident	88.1	Confident	84 Å²	84	64.5 Å²	64.5	41%	0.414	36%	0.355	S	S	.	.	G	3₁₀ helix	trans	-62.9	-21.3	179.5	-65.6	-155	107.2	0	0	113.4	S177 L181 N182 K204 M208	S177-M179 PolarHBondContact O-N 3.36Å; S177-M179 VanDerWaalsContact O-N 3.12Å; M179-L181 PolarHBondContact O-N 2.91Å; M179-N182 WeakPolarHBondContact O-CB 3.32Å; M179-N182 PolarHBondContact O-N 3.47Å; M179-K204 VanDerWaalsContact CE-CE 3.42Å; M179-K204 VanDerWaalsContact SD-CE 3.53Å; M179-M208 HydrophobicContact CB-CE 3.77Å; M179-M208 HydrophobicContact CB-SD 3.81Å; M179-M208 HydrophobicContact CG-CE 4.28Å; M179-M208 HydrophobicContact CG-SD 4.47Å; M179-M208 HydrophobicContact SD-CE 4.46Å; M179-M208 HydrophobicContact SD-SD 4.16Å
180	L	83.4	Confident	87.4	Confident	19 Å²	19	69.7 Å²	69.7	10%	0.099	39%	0.392	C	S	.	.	G	3₁₀ helix	trans	-68.9	-24.2	175	-63.8	169.7	0	0	0	112.1	Y126 S177 V178 N182 N183	Y126-L180 HydrophobicContact CD2-CD1 3.35Å; Y126-L180 HydrophobicContact CD2-CD2 4.43Å; Y126-L180 HydrophobicContact CE2-CD1 4.15Å; Y126-L180 HydrophobicContact CE2-CD2 4.46Å; Y126-L180 HydrophobicContact CG-CD1 3.64Å; S177-L180 VanDerWaalsContact O-CB 3.27Å; S177-L180 WeakPolarHBondContact O-CB 3.41Å; S177-L180 PolarHBondContact O-N 2.89Å; V178-L180 PolarHBondContact O-N 3.37Å; V178-L180 VanDerWaalsContact O-N 3.12Å; L180-N182 PolarHBondContact O-N 2.97Å; L180-N183 PolarHBondContact O-N 3.31Å
181	L	86.4	Confident	86.8	Confident	51 Å²	51	69.9 Å²	69.9	27%	0.267	40%	0.398	S	S	.	.	G	3₁₀ helix	trans	-69	-12.3	173.6	-64.7	172.1	0	0	0	112.3	R119 Y123 V178 M179 N183	R119-L181 HydrophobicContact CB-CD2 4.02Å; R119-L181 WeakPolarHBondContact CD-O 3.49Å; R119-L181 WeakPolarHBondContact CG-O 3.04Å; R119-L181 PolarHBondContact NH1-O 3.38Å; Y123-L181 HydrophobicContact CD1-CD2 4.25Å; Y123-L181 HydrophobicContact CD2-CD1 4.08Å; Y123-L181 HydrophobicContact CD2-CD2 4.04Å; Y123-L181 HydrophobicContact CD2-CG 3.72Å; Y123-L181 HydrophobicContact CE2-CD1 4.14Å; Y123-L181 HydrophobicContact CE2-CG 4.27Å; Y123-L181 HydrophobicContact CG-CD1 4.41Å; Y123-L181 HydrophobicContact CG-CD2 3.7Å; Y123-L181 HydrophobicContact CG-CG 3.95Å; V178-L181 HydrophobicContact CG2-CD1 4.23Å; V178-L181 VanDerWaalsContact O-CB 3.3Å; V178-L181 WeakPolarHBondContact O-CB 3.43Å; V178-L181 PolarHBondContact O-N 3.47Å; M179-L181 PolarHBondContact O-N 2.91Å; L181-N183 VanDerWaalsContact C-N 3.33Å
182	N	82.5	Confident	86.3	Confident	103 Å²	103	67.2 Å²	67.2	55%	0.551	39%	0.385	S	S	*	.	G	3₁₀ helix	trans	-80.2	-17.9	175.9	-66	3.6	0	0	0	112.5	R119 M179 L180 G184	R119-N182 PolarHBondContact NH1-O 2.87Å; M179-N182 WeakPolarHBondContact O-CB 3.32Å; M179-N182 PolarHBondContact O-N 3.47Å; L180-N182 PolarHBondContact O-N 2.97Å; N182-G184 PolarHBondContact O-N 3.16Å
183	N	76.7	Confident	85.8	Confident	45 Å²	45	63.5 Å²	63.5	24%	0.241	37%	0.37	C	S	.	.			trans	-92.4	99.1	179.4	-69.6	15.1	0	0	0	109.4	L180 L181	L180-N183 PolarHBondContact O-N 3.31Å; L181-N183 VanDerWaalsContact C-N 3.33Å
184	G	80.8	Confident	85.2	Confident	15 Å²	15	63.6 Å²	63.6	16%	0.155	37%	0.371	C	S	.	.			trans	-88.1	-167.6	180	0	0	0	0	0	113.8	D115 N182	D115-G184 WeakPolarHBondContact OD1-CA 3.29Å; N182-G184 PolarHBondContact O-N 3.16Å
185	S	84.4	Confident	84.3	Confident	31 Å²	31	62.1 Å²	62.1	22%	0.217	36%	0.364	C	S	.	.			trans	-76.3	144.3	169.5	56.9	0	0	0	0	110.9	D115 S193	D115-S185 WeakPolarHBondContact CA-OG 3.32Å; D115-S185 PolarHBondContact OD1-N 3.41Å; D115-S185 PolarHBondContact OD1-OG 3.41Å; S185-S193 WeakPolarHBondContact CA-O 3.24Å
186	E	84.8	Confident	83.3	Confident	90 Å²	90	62.4 Å²	62.4	42%	0.421	36%	0.355	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.2	133.3	-178.4	-70.8	177.2	-165.1	0	0	111.1	K188 S193 N198	E186-K188 PolarHBondContact O-N 3.46Å; E186-S193 PolarHBondContact N-O 3.26Å; E186-S193 PolarHBondContact O-N 3.43Å; E186-N198 PolarHBondContact OE1-ND2 2.87Å; E186-N198 PolarHBondContact OE2-ND2 2.87Å
187	Q	83.9	Confident	82.1	Confident	165 Å²	165	63.4 Å²	63.4	77%	0.771	36%	0.356	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-77.4	119.7	176	-171.6	171.4	14.2	0	0	110
188	K	79.8	Confident	81	Confident	135 Å²	135	65.2 Å²	65.2	59%	0.587	37%	0.365	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-123.2	86.5	180	-167.5	177.2	-178.6	-179.8	0	109.3	E186 S190 V191 E196	E186-K188 PolarHBondContact O-N 3.46Å; K188-S190 PolarHBondContact O-N 3.45Å; K188-V191 PolarHBondContact N-O 3.27Å; K188-V191 VanDerWaalsContact O-CG2 3.3Å; K188-V191 WeakPolarHBondContact O-CG2 3.27Å; K188-V191 PolarHBondContact O-N 3.49Å; K188-E196 IonicContact NZ-OE2 3.69Å
189	G	81.9	Confident	79.5	Confident	66 Å²	66	66.7 Å²	66.7	68%	0.68	37%	0.37	S	S	*	.	T	Hydrogen-bonded Turn	trans	69.5	-122.7	-172.2	0	0	0	0	0	111
190	S	83.4	Confident	78.4	Confident	119 Å²	119	73.1 Å²	73.1	83%	0.832	39%	0.391	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.7	-3.2	-179.4	61.8	0	0	0	0	114.6	K188	K188-S190 PolarHBondContact O-N 3.45Å
191	V	86.6	Confident	77.7	Confident	52 Å²	52	73.3 Å²	73.3	32%	0.315	39%	0.393	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-117.4	150.3	-178.6	-74	0	0	0	0	111.6	D110 K188	D110-V191 HydrophobicContact CB-CB 4.34Å; D110-V191 HydrophobicContact CB-CG1 3.97Å; K188-V191 PolarHBondContact N-O 3.27Å; K188-V191 VanDerWaalsContact O-CG2 3.3Å; K188-V191 WeakPolarHBondContact O-CG2 3.27Å; K188-V191 PolarHBondContact O-N 3.49Å
192	I	86.7	Confident	77.1	Confident	68 Å²	68	71.6 Å²	71.6	35%	0.349	38%	0.384	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-99	109.2	175	-60.4	171.9	0	0	0	107.8	D110 W111	D110-I192 PolarHBondContact OD1-N 3.28Å; W111-I192 HydrophobicContact CB-CB 4.46Å; W111-I192 HydrophobicContact CB-CG2 4.16Å; W111-I192 VanDerWaalsContact CB-O 3.26Å; W111-I192 WeakPolarHBondContact CB-O 3.46Å; W111-I192 PolarHBondContact N-O 3.12Å
193	S	84.8	Confident	76.9	Confident	13 Å²	13	71.9 Å²	71.9	9%	0.091	39%	0.389	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.2	140.3	178.7	-175.7	0	0	0	0	110.9	Y104 S185 E186 E196	Y104-S193 PolarHBondContact OH-OG 3.02Å; S185-S193 WeakPolarHBondContact CA-O 3.24Å; E186-S193 PolarHBondContact N-O 3.26Å; E186-S193 PolarHBondContact O-N 3.43Å; S193-E196 WeakPolarHBondContact OG-CG 3.19Å; S193-E196 PolarHBondContact OG-OE2 3.45Å
194	C	83.3	Confident	77.1	Confident	2 Å²	2	73 Å²	73	1%	0.014	39%	0.392	C	S	.	.			trans	-137	157.2	172.7	-177.3	0	0	0	0	109	Y104 W111 C118 E196	Y104-C194 WeakPolarHBondContact CE1-O 3.4Å; Y104-C194 HydrophobicContact CE2-CB 4.24Å; Y104-C194 PolarHBondContact OH-N 3.17Å; Y104-C194 VanDerWaalsContact OH-N 3.16Å; Y104-C194 PolarHBondContact OH-O 2.92Å; W111-C194 HydrophobicContact CB-CB 3.8Å; W111-C194 HydrophobicContact CD2-CB 3.81Å; W111-C194 HydrophobicContact CE3-CB 4.01Å; W111-C194 HydrophobicContact CG-CB 3.72Å; C118-C194 WeakPolarHBondContact CA-SG 3.35Å; C118-C194 HydrophobicContact CB-CB 4.03Å; C118-C194 WeakPolarHBondContact CB-SG 3.44Å; C118-C194 WeakPolarHBondContact SG-CB 3.33Å; C118-C194 CovalentContact SG-SG 2.02Å; C118-C194 PolarHBondContact SG-SG 3.43Å; C194-E196 PolarHBondContact O-N 2.94Å; C194-E196 VanDerWaalsContact O-N 3.08Å
195	L	76.4	Confident	77	Confident	50 Å²	50	73 Å²	73	26%	0.262	39%	0.388	S	S	.	.	S	Bend	trans	66	4.6	177.3	-54	169	0	0	0	115.8	R101 Y104 M121	R101-L195 HydrophobicContact CB-CD1 4.48Å; R101-L195 HydrophobicContact CG-CD1 3.97Å; Y104-L195 HydrophobicContact CD1-CD1 4.38Å; M121-L195 HydrophobicContact CB-CD2 3.66Å; M121-L195 HydrophobicContact CB-CG 4.47Å
196	E	72.6	Confident	77	Confident	67 Å²	67	74 Å²	74	31%	0.313	39%	0.39	S	S	.	.			trans	-86.8	152.5	175.9	-68.6	-167.7	160.8	0	0	112.5	K44 K188 S193 C194 N198	K44-E196 IonicContact NZ-OE1 3.88Å; K188-E196 IonicContact NZ-OE2 3.69Å; S193-E196 WeakPolarHBondContact OG-CG 3.19Å; S193-E196 PolarHBondContact OG-OE2 3.45Å; C194-E196 PolarHBondContact O-N 2.94Å; C194-E196 VanDerWaalsContact O-N 3.08Å; E196-N198 PolarHBondContact O-N 3.17Å
197	L	65.4	Low	77.1	Confident	76 Å²	76	73.5 Å²	73.5	40%	0.398	39%	0.393	S	S	.	.			trans	-78	108.8	177.9	-152.6	85.7	0	0	0	109.1	I202 L205 L278	L197-I202 HydrophobicContact CD2-CD1 4.45Å; L197-I202 HydrophobicContact CD2-CG1 4.41Å; L197-L205 HydrophobicContact CD1-CD1 3.7Å; L197-L205 HydrophobicContact CG-CD1 3.83Å; L197-L278 HydrophobicContact CD1-CD2 4.32Å; L197-L278 HydrophobicContact CD2-CD2 3.82Å
198	N	65.1	Low	77.1	Confident	41 Å²	41	67.7 Å²	67.7	22%	0.219	37%	0.366	C	S	.	.			trans	-77.8	129.7	176.8	-173	-13.9	0	0	0	111.9	E186 E196 Y200 T201	E186-N198 PolarHBondContact OE1-ND2 2.87Å; E186-N198 PolarHBondContact OE2-ND2 2.87Å; E196-N198 PolarHBondContact O-N 3.17Å; N198-Y200 VanDerWaalsContact C-N 3.28Å; N198-Y200 PolarHBondContact O-N 3.03Å; N198-Y200 PolarHBondContact OD1-N 3.27Å; N198-T201 PolarHBondContact O-N 2.95Å; N198-T201 VanDerWaalsContact O-N 3.16Å
199	L	57.4	Low	77.5	Confident	108 Å²	108	61.3 Å²	61.3	57%	0.565	34%	0.338	S	S	*	.	G	3₁₀ helix	trans	-47.6	-41.8	173.1	-63.5	166.7	0	0	0	113.6	T201 W281	L199-T201 PolarHBondContact O-N 3.47Å; L199-T201 VanDerWaalsContact O-N 3.14Å; L199-W281 HydrophobicContact CD2-CH2 3.23Å; L199-W281 HydrophobicContact CD2-CZ2 3.24Å
200	Y	60.3	Low	77.9	Confident	219 Å²	219	64 Å²	64	86%	0.859	33%	0.329	S	S	*	.	G	3₁₀ helix	trans	-71.8	-9.5	-174.6	-150.3	-97	0	0	0	113.3	N198	N198-Y200 VanDerWaalsContact C-N 3.28Å; N198-Y200 PolarHBondContact O-N 3.03Å; N198-Y200 PolarHBondContact OD1-N 3.27Å
201	T	67.9	Low	78.1	Confident	24 Å²	24	63.2 Å²	63.2	15%	0.147	31%	0.314	C	S	.	.	G	3₁₀ helix	trans	-118.5	8.1	-172.1	-41.1	0	0	0	0	113	N198 L199 T203 K204 L205	N198-T201 PolarHBondContact O-N 2.95Å; N198-T201 VanDerWaalsContact O-N 3.16Å; L199-T201 PolarHBondContact O-N 3.47Å; L199-T201 VanDerWaalsContact O-N 3.14Å; T201-T203 PolarHBondContact O-N 3.36Å; T201-K204 HydrophobicContact CG2-CB 3.85Å; T201-K204 HydrophobicContact CG2-CD 3.84Å; T201-K204 HydrophobicContact CG2-CG 4.26Å; T201-K204 PolarHBondContact O-N 3.1Å; T201-K204 VanDerWaalsContact O-N 3.14Å; T201-L205 HydrophobicContact CG2-CG 4.27Å; T201-L205 WeakPolarHBondContact O-CB 3.19Å; T201-L205 WeakPolarHBondContact O-CG 3.2Å; T201-L205 PolarHBondContact O-N 3.3Å
202	I	74.4	Confident	78.3	Confident	15 Å²	15	61.4 Å²	61.4	8%	0.077	31%	0.305	C	S	.	.	H	α-helix	trans	-62.3	-43	-171	-76.2	-176.6	0	0	0	113.4	L197 K204 L205 Q206 W281	L197-I202 HydrophobicContact CD2-CD1 4.45Å; L197-I202 HydrophobicContact CD2-CG1 4.41Å; I202-K204 VanDerWaalsContact C-N 3.29Å; I202-K204 PolarHBondContact O-N 2.89Å; I202-L205 PolarHBondContact O-N 3.42Å; I202-Q206 HydrophobicContact CG2-CG 4.28Å; I202-Q206 WeakPolarHBondContact O-CB 3.2Å; I202-Q206 WeakPolarHBondContact O-CG 3.29Å; I202-Q206 PolarHBondContact O-N 3.25Å; I202-W281 HydrophobicContact CD1-CD2 3.35Å; I202-W281 HydrophobicContact CD1-CE3 3.26Å; I202-W281 HydrophobicContact CD1-CG 4.23Å; I202-W281 HydrophobicContact CD1-CH2 3.21Å; I202-W281 HydrophobicContact CD1-CZ2 3.34Å; I202-W281 HydrophobicContact CD1-CZ3 3.19Å; I202-W281 HydrophobicContact CG2-CE3 4.29Å
203	T	77.8	Confident	78.5	Confident	108 Å²	108	59.6 Å²	59.6	66%	0.663	30%	0.296	S	S	*	.	H	α-helix	trans	-60	-42.1	176.7	-46.1	0	0	0	0	111.2	T201 Q206 T207	T201-T203 PolarHBondContact O-N 3.36Å; T203-Q206 PolarHBondContact O-N 3.03Å; T203-T207 PolarHBondContact O-N 2.84Å; T203-T207 PolarHBondContact O-OG1 2.83Å; T203-T207 VanDerWaalsContact O-OG1 3.11Å
204	K	80.9	Confident	78.8	Confident	70 Å²	70	62.7 Å²	62.7	30%	0.304	31%	0.314	S	S	.	.	H	α-helix	trans	-66.5	-42.4	176.5	-176.7	-179	176.4	-169.8	0	111.4	M179 T201 I202 Q206 T207 M208	M179-K204 VanDerWaalsContact CE-CE 3.42Å; M179-K204 VanDerWaalsContact SD-CE 3.53Å; T201-K204 HydrophobicContact CG2-CB 3.85Å; T201-K204 HydrophobicContact CG2-CD 3.84Å; T201-K204 HydrophobicContact CG2-CG 4.26Å; T201-K204 PolarHBondContact O-N 3.1Å; T201-K204 VanDerWaalsContact O-N 3.14Å; I202-K204 VanDerWaalsContact C-N 3.29Å; I202-K204 PolarHBondContact O-N 2.89Å; K204-Q206 VanDerWaalsContact C-N 3.35Å; K204-T207 PolarHBondContact O-N 3.23Å; K204-M208 WeakPolarHBondContact O-CB 3.49Å; K204-M208 WeakPolarHBondContact O-CG 3.17Å; K204-M208 PolarHBondContact O-N 2.93Å
205	L	79.8	Confident	79.2	Confident	13 Å²	13	65 Å²	65	7%	0.068	33%	0.328	C	S	.	.	H	α-helix	trans	-64.9	-37	177.1	-74.7	163.9	0	0	0	112.3	L197 T201 I202 N209	L197-L205 HydrophobicContact CD1-CD1 3.7Å; L197-L205 HydrophobicContact CG-CD1 3.83Å; T201-L205 HydrophobicContact CG2-CG 4.27Å; T201-L205 WeakPolarHBondContact O-CB 3.19Å; T201-L205 WeakPolarHBondContact O-CG 3.2Å; T201-L205 PolarHBondContact O-N 3.3Å; I202-L205 PolarHBondContact O-N 3.42Å; L205-N209 VanDerWaalsContact O-CB 3.23Å; L205-N209 WeakPolarHBondContact O-CB 3.48Å; L205-N209 PolarHBondContact O-N 2.87Å
206	Q	84	Confident	79.8	Confident	54 Å²	54	62.9 Å²	62.9	25%	0.252	32%	0.318	S	S	.	.	H	α-helix	trans	-64.2	-50.1	173.2	-77.1	175.5	-17.8	0	0	110.9	I202 T203 K204 M208 N209 Y210 L278	I202-Q206 HydrophobicContact CG2-CG 4.28Å; I202-Q206 WeakPolarHBondContact O-CB 3.2Å; I202-Q206 WeakPolarHBondContact O-CG 3.29Å; I202-Q206 PolarHBondContact O-N 3.25Å; T203-Q206 PolarHBondContact O-N 3.03Å; K204-Q206 VanDerWaalsContact C-N 3.35Å; Q206-M208 PolarHBondContact O-N 3.3Å; Q206-N209 WeakPolarHBondContact O-CB 3.07Å; Q206-N209 PolarHBondContact O-N 3.32Å; Q206-N209 VanDerWaalsContact O-N 3.11Å; Q206-Y210 WeakPolarHBondContact O-CD2 3.44Å; Q206-Y210 PolarHBondContact O-N 3.3Å; Q206-L278 HydrophobicContact CG-CB 4.24Å; Q206-L278 PolarHBondContact NE2-O 3.37Å
207	T	86.1	Confident	80.7	Confident	79 Å²	79	59.9 Å²	59.9	49%	0.485	30%	0.304	S	S	.	.	H	α-helix	trans	-58.6	-47	176.4	-58.6	0	0	0	0	111.5	T203 K204 N209 Y210 I211	T203-T207 PolarHBondContact O-N 2.84Å; T203-T207 PolarHBondContact O-OG1 2.83Å; T203-T207 VanDerWaalsContact O-OG1 3.11Å; K204-T207 PolarHBondContact O-N 3.23Å; T207-N209 VanDerWaalsContact C-N 3.31Å; T207-N209 PolarHBondContact O-N 2.85Å; T207-Y210 PolarHBondContact O-N 3.47Å; T207-I211 HydrophobicContact CG2-CD1 4.29Å; T207-I211 WeakPolarHBondContact O-CG1 3.5Å; T207-I211 PolarHBondContact O-N 3.35Å; T207-I211 VanDerWaalsContact O-N 3.1Å
208	M	85.3	Confident	82	Confident	42 Å²	42	59 Å²	59	21%	0.207	30%	0.3	C	S	.	.	H	α-helix	trans	-62.8	-37.2	175.6	-71.5	-162.8	81.2	0	0	112.2	M179 K204 Q206 I211 A212	M179-M208 HydrophobicContact CB-CE 3.77Å; M179-M208 HydrophobicContact CB-SD 3.81Å; M179-M208 HydrophobicContact CG-CE 4.28Å; M179-M208 HydrophobicContact CG-SD 4.47Å; M179-M208 HydrophobicContact SD-CE 4.46Å; M179-M208 HydrophobicContact SD-SD 4.16Å; K204-M208 WeakPolarHBondContact O-CB 3.49Å; K204-M208 WeakPolarHBondContact O-CG 3.17Å; K204-M208 PolarHBondContact O-N 2.93Å; Q206-M208 PolarHBondContact O-N 3.3Å; M208-I211 PolarHBondContact O-N 3.48Å; M208-A212 WeakPolarHBondContact O-CB 3.2Å; M208-A212 PolarHBondContact O-N 3.02Å
209	N	88.3	Confident	83.3	Confident	1 Å²	1	61.7 Å²	61.7	1%	0.005	31%	0.313	C	S	.	.	H	α-helix	trans	-62.3	-41.5	174	179.4	74.6	0	0	0	112.1	L205 Q206 T207 A212 L213 R274 T275 L278	L205-N209 VanDerWaalsContact O-CB 3.23Å; L205-N209 WeakPolarHBondContact O-CB 3.48Å; L205-N209 PolarHBondContact O-N 2.87Å; Q206-N209 WeakPolarHBondContact O-CB 3.07Å; Q206-N209 PolarHBondContact O-N 3.32Å; Q206-N209 VanDerWaalsContact O-N 3.11Å; T207-N209 VanDerWaalsContact C-N 3.31Å; T207-N209 PolarHBondContact O-N 2.85Å; N209-A212 PolarHBondContact O-N 3.42Å; N209-L213 WeakPolarHBondContact O-CB 3.26Å; N209-L213 PolarHBondContact O-N 3Å; N209-R274 VanDerWaalsContact CG-NH1 3.3Å; N209-R274 PolarHBondContact OD1-NH1 3.08Å; N209-T275 PolarHBondContact ND2-OG1 2.86Å; N209-L278 HydrophobicContact CB-CD1 3.47Å; N209-L278 VanDerWaalsContact CB-CD1 3.47Å
210	Y	88.6	Confident	85	Confident	122 Å²	122	56.6 Å²	56.6	48%	0.478	29%	0.287	S	S	.	.	H	α-helix	trans	-63.5	-46.4	176.9	-82.5	-69.4	0	0	0	111.9	Q206 T207 A212 L213 V214	Q206-Y210 WeakPolarHBondContact O-CD2 3.44Å; Q206-Y210 PolarHBondContact O-N 3.3Å; T207-Y210 PolarHBondContact O-N 3.47Å; Y210-A212 PolarHBondContact O-N 3.43Å; Y210-L213 PolarHBondContact O-N 3.45Å; Y210-V214 WeakPolarHBondContact O-CG2 3.23Å; Y210-V214 PolarHBondContact O-N 3.32Å
211	I	88.9	Confident	86.4	Confident	103 Å²	103	48 Å²	48	53%	0.528	25%	0.254	S	S	.	.	H	α-helix	trans	-60.8	-47.9	176.8	-63.2	169	0	0	0	110.1	T207 M208 L213 V214 V215	T207-I211 HydrophobicContact CG2-CD1 4.29Å; T207-I211 WeakPolarHBondContact O-CG1 3.5Å; T207-I211 PolarHBondContact O-N 3.35Å; T207-I211 VanDerWaalsContact O-N 3.1Å; M208-I211 PolarHBondContact O-N 3.48Å; I211-L213 PolarHBondContact O-N 2.85Å; I211-V214 PolarHBondContact O-N 3.12Å; I211-V215 HydrophobicContact CG2-CG2 4.36Å; I211-V215 WeakPolarHBondContact O-CB 3.27Å; I211-V215 PolarHBondContact O-N 2.93Å
212	A	89.6	Confident	87.5	Confident	15 Å²	15	52.6 Å²	52.6	12%	0.124	27%	0.272	C	S	.	.	H	α-helix	trans	-58.4	-43.2	176	0	0	0	0	0	113.4	Y130 M208 N209 Y210 G216 F217	Y130-A212 HydrophobicContact CE1-CB 4.3Å; Y130-A212 WeakPolarHBondContact OH-CB 3.43Å; M208-A212 WeakPolarHBondContact O-CB 3.2Å; M208-A212 PolarHBondContact O-N 3.02Å; N209-A212 PolarHBondContact O-N 3.42Å; Y210-A212 PolarHBondContact O-N 3.43Å; A212-G216 CarbonylContact O-C 3.36Å; A212-G216 WeakPolarHBondContact O-CA 3.41Å; A212-G216 PolarHBondContact O-N 2.88Å; A212-F217 PolarHBondContact O-N 2.93Å
213	L	91	Very high	88.2	Confident	29 Å²	29	54.2 Å²	54.2	15%	0.152	28%	0.283	C	S	.	.	H	α-helix	trans	-64.9	-48.1	179.5	177.7	66.9	0	0	0	110.4	N209 Y210 I211 F217 L218 H271 T275	N209-L213 WeakPolarHBondContact O-CB 3.26Å; N209-L213 PolarHBondContact O-N 3Å; Y210-L213 PolarHBondContact O-N 3.45Å; I211-L213 PolarHBondContact O-N 2.85Å; L213-F217 HydrophobicContact CD1-CD1 4.23Å; L213-F217 WeakPolarHBondContact O-CB 3.37Å; L213-F217 PolarHBondContact O-N 3.39Å; L213-L218 HydrophobicContact CD1-CG 4.45Å; L213-L218 HydrophobicContact CG-CD1 4.16Å; L213-L218 HydrophobicContact CG-CG 4.37Å; L213-L218 WeakPolarHBondContact O-CG 3.42Å; L213-L218 PolarHBondContact O-N 2.82Å; L213-H271 HydrophobicContact CD1-CB 3.91Å; L213-T275 HydrophobicContact CD2-CG2 4.16Å
214	V	91.3	Very high	88.7	Confident	78 Å²	78	49.1 Å²	49.1	47%	0.473	25%	0.252	S	S	.	.	I	π-helix	trans	-72.2	-57	-176.3	174.9	0	0	0	0	111	Y210 I211 L218 L219	Y210-V214 WeakPolarHBondContact O-CG2 3.23Å; Y210-V214 PolarHBondContact O-N 3.32Å; I211-V214 PolarHBondContact O-N 3.12Å; V214-L218 PolarHBondContact O-N 2.02Å; V214-L219 WeakPolarHBondContact O-CB 3.46Å; V214-L219 PolarHBondContact O-N 2.65Å
215	V	91.8	Very high	89	Confident	52 Å²	52	47.5 Å²	47.5	32%	0.315	25%	0.249	S	C	.	.	I	π-helix	trans	-81.7	-43.6	-171.8	-177.4	0	0	0	0	110.9	Y134 F172 I211 P220	Y134-V215 PolarHBondContact OH-O 3.19Å; F172-V215 HydrophobicContact CE1-CG1 4.47Å; F172-V215 HydrophobicContact CZ-CG1 3.83Å; I211-V215 HydrophobicContact CG2-CG2 4.36Å; I211-V215 WeakPolarHBondContact O-CB 3.27Å; I211-V215 PolarHBondContact O-N 2.93Å; V215-P220 VanDerWaalsContact O-CD 3.24Å; V215-P220 WeakPolarHBondContact O-CD 3.37Å
216	G	89.3	Confident	89.3	Confident	5 Å²	5	51.8 Å²	51.8	5%	0.052	27%	0.271	C	S	.	.	I	π-helix	trans	-82.6	-17.4	-174.6	0	0	0	0	0	114.9	I133 A212	I133-G216 WeakPolarHBondContact CD1-O 3.48Å; I133-G216 WeakPolarHBondContact CG2-O 3.33Å; A212-G216 CarbonylContact O-C 3.36Å; A212-G216 WeakPolarHBondContact O-CA 3.41Å; A212-G216 PolarHBondContact O-N 2.88Å
217	F	91.8	Very high	89.3	Confident	3 Å²	3	49.8 Å²	49.8	1%	0.013	26%	0.263	C	S	.	.	I	π-helix	trans	-130.6	-59.1	-178.2	178.6	-102.6	0	0	0	114.3	A212 L213 L219 P220 F221 F263 F267 L268 H271	A212-F217 PolarHBondContact O-N 2.93Å; L213-F217 HydrophobicContact CD1-CD1 4.23Å; L213-F217 WeakPolarHBondContact O-CB 3.37Å; L213-F217 PolarHBondContact O-N 3.39Å; F217-L219 PolarHBondContact O-N 3.45Å; F217-P220 WeakPolarHBondContact O-CD 3.42Å; F217-F221 HydrophobicContact CZ-CB 4.48Å; F217-F221 HydrophobicContact CZ-CD2 4.31Å; F217-F221 VanDerWaalsContact O-CB 3.25Å; F217-F221 WeakPolarHBondContact O-CB 3.14Å; F217-F221 PolarHBondContact O-N 3.31Å; F217-F263 AromaticContact CE2-CD1 3.96Å; F217-F263 HydrophobicContact CE2-CD1 3.96Å; F217-F263 HydrophobicContact CE2-CE1 4.45Å; F217-F267 HydrophobicContact CD2-CB 3.99Å; F217-F267 HydrophobicContact CE2-CB 3.69Å; F217-L268 HydrophobicContact CE1-CD1 3.59Å; F217-L268 HydrophobicContact CE2-CB 4.38Å; F217-L268 HydrophobicContact CZ-CB 3.72Å; F217-L268 HydrophobicContact CZ-CD1 3.55Å; F217-L268 HydrophobicContact CZ-CG 4.24Å; F217-H271 HydrophobicContact CD1-CB 4.17Å; F217-H271 AromaticContact CD2-CD2 3.45Å; F217-H271 VanDerWaalsContact CD2-CD2 3.45Å; F217-H271 WeakPolarHBondContact CD2-CD2 3.4Å; F217-H271 HydrophobicContact CG-CB 4.25Å; F217-H271 AromaticContact CG-CD2 3.52Å; F217-H271 AromaticContact CG-CG 3.88Å
218	L	92.1	Very high	89.2	Confident	59 Å²	59	46.5 Å²	46.5	31%	0.309	24%	0.241	S	C	.	.	I	π-helix	trans	-63.2	-46.3	-174	-70.2	176.8	0	0	0	111.9	L213 V214 F221 F222	L213-L218 HydrophobicContact CD1-CG 4.45Å; L213-L218 HydrophobicContact CG-CD1 4.16Å; L213-L218 HydrophobicContact CG-CG 4.37Å; L213-L218 WeakPolarHBondContact O-CG 3.42Å; L213-L218 PolarHBondContact O-N 2.82Å; V214-L218 PolarHBondContact O-N 2.02Å; L218-F221 PolarHBondContact O-N 3.41Å; L218-F222 HydrophobicContact CB-CD2 4.26Å; L218-F222 HydrophobicContact CB-CE2 4.1Å; L218-F222 HydrophobicContact CD2-CE2 4.32Å; L218-F222 WeakPolarHBondContact O-CD2 3.27Å; L218-F222 PolarHBondContact O-N 3.4Å
219	L	92.9	Very high	89.2	Confident	96 Å²	96	49.4 Å²	49.4	50%	0.503	26%	0.257	S	S	.	.	H	α-helix	trans	-57.5	-52.3	177.4	174.1	80.8	0	0	0	112.3	V214 F217 F221 F222 T223	V214-L219 WeakPolarHBondContact O-CB 3.46Å; V214-L219 PolarHBondContact O-N 2.65Å; F217-L219 PolarHBondContact O-N 3.45Å; L219-F221 PolarHBondContact O-N 3.36Å; L219-F222 PolarHBondContact O-N 2.99Å; L219-T223 WeakPolarHBondContact O-CB 3.23Å; L219-T223 PolarHBondContact O-N 2.92Å; L219-T223 PolarHBondContact O-OG1 3.05Å
220	P	92.3	Very high	89	Confident	2 Å²	2	52.8 Å²	52.8	1%	0.013	28%	0.275	C	S	.	.	H	α-helix	trans	-54	-46.6	169.9	-31	35.3	0	0	0	114	I133 Y134 T137 V215 F217 F222 T223 L224 F263	I133-P220 HydrophobicContact CG2-CB 3.41Å; I133-P220 VanDerWaalsContact CG2-CB 3.41Å; I133-P220 HydrophobicContact CG2-CG 3.53Å; Y134-P220 HydrophobicContact CE1-CG 4.14Å; T137-P220 WeakPolarHBondContact OG1-CB 3.31Å; V215-P220 VanDerWaalsContact O-CD 3.24Å; V215-P220 WeakPolarHBondContact O-CD 3.37Å; F217-P220 WeakPolarHBondContact O-CD 3.42Å; P220-F222 PolarHBondContact O-N 3.36Å; P220-T223 PolarHBondContact O-N 3.45Å; P220-L224 WeakPolarHBondContact O-CB 3.45Å; P220-L224 WeakPolarHBondContact O-CG 3.28Å; P220-L224 PolarHBondContact O-N 2.94Å; P220-F263 HydrophobicContact CB-CE1 4.34Å; P220-F263 HydrophobicContact CB-CZ 4.47Å
221	F	90.5	Very high	88.5	Confident	39 Å²	39	47 Å²	47	17%	0.171	25%	0.252	C	S	.	.	H	α-helix	trans	-61.4	-43.8	-178.9	178	-94.9	0	0	0	112.5	F217 L218 L219 L224 S225 F263 F264	F217-F221 HydrophobicContact CZ-CB 4.48Å; F217-F221 HydrophobicContact CZ-CD2 4.31Å; F217-F221 VanDerWaalsContact O-CB 3.25Å; F217-F221 WeakPolarHBondContact O-CB 3.14Å; F217-F221 PolarHBondContact O-N 3.31Å; L218-F221 PolarHBondContact O-N 3.41Å; L219-F221 PolarHBondContact O-N 3.36Å; F221-L224 PolarHBondContact O-N 2.97Å; F221-S225 WeakPolarHBondContact O-CB 3.41Å; F221-S225 PolarHBondContact O-N 3.42Å; F221-S225 PolarHBondContact O-OG 3.48Å; F221-F263 HydrophobicContact CD2-CD1 4.23Å; F221-F264 AromaticContact CE2-CE1 3.95Å; F221-F264 HydrophobicContact CE2-CE1 3.95Å; F221-F264 AromaticContact CE2-CZ 3.92Å; F221-F264 HydrophobicContact CE2-CZ 3.92Å; F221-F264 HydrophobicContact CZ-CE1 4.13Å; F221-F264 HydrophobicContact CZ-CZ 4.07Å
222	F	90.8	Very high	88.1	Confident	119 Å²	119	45.9 Å²	45.9	52%	0.522	25%	0.247	S	C	.	.	H	α-helix	trans	-67.5	-40.5	176	-75.2	-62.2	0	0	0	111.8	L218 L219 P220 L224 S225 I226	L218-F222 HydrophobicContact CB-CD2 4.26Å; L218-F222 HydrophobicContact CB-CE2 4.1Å; L218-F222 HydrophobicContact CD2-CE2 4.32Å; L218-F222 WeakPolarHBondContact O-CD2 3.27Å; L218-F222 PolarHBondContact O-N 3.4Å; L219-F222 PolarHBondContact O-N 2.99Å; P220-F222 PolarHBondContact O-N 3.36Å; F222-L224 VanDerWaalsContact C-N 3.33Å; F222-L224 PolarHBondContact O-N 2.71Å; F222-S225 PolarHBondContact O-N 3.31Å; F222-I226 WeakPolarHBondContact O-CG1 3.45Å; F222-I226 PolarHBondContact O-N 3.3Å
223	T	89.3	Confident	87.8	Confident	49 Å²	49	53.2 Å²	53.2	30%	0.301	27%	0.271	S	S	.	.	H	α-helix	trans	-59.5	-45.9	175.2	-62.8	0	0	0	0	110.8	T137 V141 L219 P220 I226 C227	T137-T223 HydrophobicContact CG2-CG2 3.85Å; V141-T223 HydrophobicContact CG2-CG2 4.06Å; L219-T223 WeakPolarHBondContact O-CB 3.23Å; L219-T223 PolarHBondContact O-N 2.92Å; L219-T223 PolarHBondContact O-OG1 3.05Å; P220-T223 PolarHBondContact O-N 3.45Å; T223-I226 PolarHBondContact O-N 3.25Å; T223-C227 WeakPolarHBondContact O-CB 3.23Å; T223-C227 PolarHBondContact O-N 3.1Å; T223-C227 PolarHBondContact O-SG 3.39Å
224	L	87.4	Confident	87.1	Confident	2 Å²	2	53 Å²	53	1%	0.01	27%	0.273	C	S	.	.	H	α-helix	trans	-61.2	-47.1	175.1	-75.6	-177	0	0	0	112.2	T137 P220 F221 F222 I226 C227 Y228 T259 F263	T137-L224 HydrophobicContact CG2-CD2 4.39Å; T137-L224 HydrophobicContact CG2-CG 4.4Å; P220-L224 WeakPolarHBondContact O-CB 3.45Å; P220-L224 WeakPolarHBondContact O-CG 3.28Å; P220-L224 PolarHBondContact O-N 2.94Å; F221-L224 PolarHBondContact O-N 2.97Å; F222-L224 VanDerWaalsContact C-N 3.33Å; F222-L224 PolarHBondContact O-N 2.71Å; L224-I226 VanDerWaalsContact C-N 3.33Å; L224-I226 PolarHBondContact O-N 2.8Å; L224-C227 PolarHBondContact O-N 3.1Å; L224-Y228 HydrophobicContact CB-CD2 4.41Å; L224-Y228 HydrophobicContact CB-CE2 3.88Å; L224-Y228 HydrophobicContact CD2-CE1 4.2Å; L224-Y228 HydrophobicContact CD2-CE2 4.34Å; L224-Y228 WeakPolarHBondContact CD2-OH 3.31Å; L224-Y228 WeakPolarHBondContact O-CB 3.49Å; L224-Y228 VanDerWaalsContact O-CD2 3.23Å; L224-Y228 WeakPolarHBondContact O-CD2 3.11Å; L224-Y228 PolarHBondContact O-N 3.43Å; L224-T259 HydrophobicContact CD1-CG2 3.82Å; L224-T259 HydrophobicContact CD2-CG2 4.45Å; L224-F263 HydrophobicContact CD1-CD1 4.16Å; L224-F263 HydrophobicContact CD1-CD2 3.73Å; L224-F263 HydrophobicContact CD1-CE1 3.76Å; L224-F263 HydrophobicContact CD1-CE2 3.28Å; L224-F263 HydrophobicContact CD1-CG 4.13Å; L224-F263 HydrophobicContact CD1-CZ 3.27Å; L224-F263 HydrophobicContact CG-CZ 4.48Å
225	S	87.6	Confident	86.4	Confident	36 Å²	36	50.7 Å²	50.7	25%	0.252	26%	0.258	S	S	.	.	H	α-helix	trans	-57.4	-46.2	179.3	-60.9	0	0	0	0	111.4	F221 F222 Y228 L229	F221-S225 WeakPolarHBondContact O-CB 3.41Å; F221-S225 PolarHBondContact O-N 3.42Å; F221-S225 PolarHBondContact O-OG 3.48Å; F222-S225 PolarHBondContact O-N 3.31Å; S225-Y228 PolarHBondContact O-N 3.25Å; S225-L229 VanDerWaalsContact O-CG 3.31Å; S225-L229 WeakPolarHBondContact O-CG 3.41Å; S225-L229 PolarHBondContact O-N 3.23Å
226	I	87.5	Confident	85.9	Confident	103 Å²	103	55.1 Å²	55.1	53%	0.528	28%	0.279	S	S	.	.	H	α-helix	trans	-63.1	-48.5	175.8	-66.6	167.2	0	0	0	110.6	F222 T223 L224 Y228 L229 L230	F222-I226 WeakPolarHBondContact O-CG1 3.45Å; F222-I226 PolarHBondContact O-N 3.3Å; T223-I226 PolarHBondContact O-N 3.25Å; L224-I226 VanDerWaalsContact C-N 3.33Å; L224-I226 PolarHBondContact O-N 2.8Å; I226-Y228 VanDerWaalsContact C-N 3.28Å; I226-Y228 PolarHBondContact O-N 3.14Å; I226-L229 PolarHBondContact O-N 3.43Å; I226-L230 HydrophobicContact CG2-CD1 3.96Å; I226-L230 HydrophobicContact CG2-CG 4.39Å; I226-L230 VanDerWaalsContact O-CG 3.31Å; I226-L230 WeakPolarHBondContact O-CG 3.31Å; I226-L230 PolarHBondContact O-N 3.12Å
227	C	83.3	Confident	85.3	Confident	11 Å²	11	63.5 Å²	63.5	7%	0.074	31%	0.314	C	S	.	.	H	α-helix	trans	-56.7	-43.7	178.8	-70.7	0	0	0	0	111.5	T223 L224 L230 I231	T223-C227 WeakPolarHBondContact O-CB 3.23Å; T223-C227 PolarHBondContact O-N 3.1Å; T223-C227 PolarHBondContact O-SG 3.39Å; L224-C227 PolarHBondContact O-N 3.1Å; C227-L230 PolarHBondContact O-N 3.49Å; C227-I231 VanDerWaalsContact O-CG1 3.29Å; C227-I231 WeakPolarHBondContact O-CG1 3.26Å; C227-I231 PolarHBondContact O-N 2.84Å
228	Y	83.8	Confident	84.4	Confident	10 Å²	10	66 Å²	66	4%	0.039	33%	0.33	C	S	.	.	H	α-helix	trans	-69.6	-40.2	-178.6	-60.5	-21.5	0	0	0	112.7	S140 L224 S225 I226 L230 I231 I232 I256 T259 L260	S140-Y228 PolarHBondContact OG-OH 3.04Å; L224-Y228 HydrophobicContact CB-CD2 4.41Å; L224-Y228 HydrophobicContact CB-CE2 3.88Å; L224-Y228 HydrophobicContact CD2-CE1 4.2Å; L224-Y228 HydrophobicContact CD2-CE2 4.34Å; L224-Y228 WeakPolarHBondContact CD2-OH 3.31Å; L224-Y228 WeakPolarHBondContact O-CB 3.49Å; L224-Y228 VanDerWaalsContact O-CD2 3.23Å; L224-Y228 WeakPolarHBondContact O-CD2 3.11Å; L224-Y228 PolarHBondContact O-N 3.43Å; S225-Y228 PolarHBondContact O-N 3.25Å; I226-Y228 VanDerWaalsContact C-N 3.28Å; I226-Y228 PolarHBondContact O-N 3.14Å; Y228-L230 VanDerWaalsContact C-N 3.28Å; Y228-L230 PolarHBondContact O-N 3.4Å; Y228-I231 HydrophobicContact CD1-CD1 4.29Å; Y228-I231 PolarHBondContact O-N 3.09Å; Y228-I232 WeakPolarHBondContact O-CB 2.98Å; Y228-I232 VanDerWaalsContact O-CG1 3.26Å; Y228-I232 WeakPolarHBondContact O-CG1 3.37Å; Y228-I232 PolarHBondContact O-N 2.82Å; Y228-I256 HydrophobicContact CD1-CB 3.9Å; Y228-I256 HydrophobicContact CD1-CD1 3.88Å; Y228-I256 HydrophobicContact CD1-CG1 3.41Å; Y228-I256 VanDerWaalsContact CD1-CG1 3.41Å; Y228-I256 HydrophobicContact CD1-CG2 3.5Å; Y228-I256 VanDerWaalsContact CD1-CG2 3.5Å; Y228-I256 HydrophobicContact CD2-CG2 3.72Å; Y228-I256 HydrophobicContact CE1-CB 3.76Å; Y228-I256 HydrophobicContact CE1-CD1 4.4Å; Y228-I256 HydrophobicContact CE1-CG1 3.45Å; Y228-I256 VanDerWaalsContact CE1-CG1 3.45Å; Y228-I256 HydrophobicContact CE1-CG2 3.68Å; Y228-I256 HydrophobicContact CE2-CG2 3.91Å; Y228-I256 HydrophobicContact CG-CB 4.39Å; Y228-I256 HydrophobicContact CG-CG1 4.25Å; Y228-I256 HydrophobicContact CG-CG2 3.48Å; Y228-I256 VanDerWaalsContact CG-CG2 3.48Å; Y228-T259 WeakPolarHBondContact OH-CB 3.47Å; Y228-T259 WeakPolarHBondContact OH-CG2 3.38Å; Y228-L260 HydrophobicContact CD2-CD1 3.85Å; Y228-L260 HydrophobicContact CD2-CD2 3.62Å; Y228-L260 HydrophobicContact CD2-CG 3.72Å; Y228-L260 HydrophobicContact CE2-CD1 4.01Å; Y228-L260 HydrophobicContact CE2-CD2 3.35Å; Y228-L260 HydrophobicContact CE2-CG 3.36Å
229	L	85.4	Confident	82.8	Confident	104 Å²	104	72.6 Å²	72.6	55%	0.545	36%	0.359	S	S	.	.	H	α-helix	trans	-58.7	-42.8	172.2	-72.7	172.4	0	0	0	111.4	S225 I226 R233	S225-L229 VanDerWaalsContact O-CG 3.31Å; S225-L229 WeakPolarHBondContact O-CG 3.41Å; S225-L229 PolarHBondContact O-N 3.23Å; I226-L229 PolarHBondContact O-N 3.43Å; L229-R233 WeakPolarHBondContact O-CB 3.48Å; L229-R233 VanDerWaalsContact O-CG 3.28Å; L229-R233 WeakPolarHBondContact O-CG 3.42Å; L229-R233 PolarHBondContact O-N 2.87Å
230	L	83.1	Confident	81.2	Confident	71 Å²	71	74.2 Å²	74.2	37%	0.372	37%	0.373	S	S	.	.	H	α-helix	trans	-69.5	-40.2	178.1	-64.2	176	0	0	0	112.4	F144 I226 C227 Y228 R233 A234	F144-L230 HydrophobicContact CD2-CB 4.22Å; F144-L230 HydrophobicContact CE1-CD1 4.3Å; F144-L230 HydrophobicContact CE2-CB 3.38Å; F144-L230 HydrophobicContact CE2-CD1 4.22Å; F144-L230 HydrophobicContact CE2-CG 4.45Å; F144-L230 HydrophobicContact CZ-CB 3.76Å; F144-L230 HydrophobicContact CZ-CD1 3.69Å; F144-L230 HydrophobicContact CZ-CG 4.37Å; I226-L230 HydrophobicContact CG2-CD1 3.96Å; I226-L230 HydrophobicContact CG2-CG 4.39Å; I226-L230 VanDerWaalsContact O-CG 3.31Å; I226-L230 WeakPolarHBondContact O-CG 3.31Å; I226-L230 PolarHBondContact O-N 3.12Å; C227-L230 PolarHBondContact O-N 3.49Å; Y228-L230 VanDerWaalsContact C-N 3.28Å; Y228-L230 PolarHBondContact O-N 3.4Å; L230-R233 PolarHBondContact O-N 3.41Å; L230-A234 WeakPolarHBondContact O-CB 3.43Å; L230-A234 PolarHBondContact O-N 3.21Å
231	I	78.2	Confident	79.8	Confident	0 Å²	0	76 Å²	76	0%	0	38%	0.384	C	S	.	.	H	α-helix	trans	-60.6	-52.8	173.7	-66.5	169.3	0	0	0	109.6	F144 C227 Y228 R233 A234 L235 I256	F144-I231 HydrophobicContact CB-CD1 3.81Å; F144-I231 HydrophobicContact CB-CG1 3.8Å; F144-I231 HydrophobicContact CD2-CD1 4.4Å; F144-I231 HydrophobicContact CD2-CG1 3.46Å; F144-I231 VanDerWaalsContact CD2-CG1 3.46Å; F144-I231 HydrophobicContact CE2-CG1 4.48Å; F144-I231 HydrophobicContact CG-CG1 4.08Å; C227-I231 VanDerWaalsContact O-CG1 3.29Å; C227-I231 WeakPolarHBondContact O-CG1 3.26Å; C227-I231 PolarHBondContact O-N 2.84Å; Y228-I231 HydrophobicContact CD1-CD1 4.29Å; Y228-I231 PolarHBondContact O-N 3.09Å; I231-R233 VanDerWaalsContact C-N 3.29Å; I231-R233 PolarHBondContact O-N 3.46Å; I231-A234 PolarHBondContact O-N 2.98Å; I231-L235 HydrophobicContact CG2-CD1 3.52Å; I231-L235 HydrophobicContact CG2-CG 3.82Å; I231-L235 WeakPolarHBondContact O-CB 3.38Å; I231-L235 WeakPolarHBondContact O-CG 3.03Å; I231-L235 PolarHBondContact O-N 2.79Å; I231-I256 HydrophobicContact CB-CD1 3.82Å; I231-I256 HydrophobicContact CD1-CD1 3.41Å; I231-I256 VanDerWaalsContact CD1-CD1 3.41Å; I231-I256 HydrophobicContact CD1-CG1 3.81Å; I231-I256 HydrophobicContact CG1-CD1 4.2Å; I231-I256 HydrophobicContact CG2-CD1 3.62Å
232	I	81.3	Confident	78.6	Confident	80 Å²	80	81.9 Å²	81.9	41%	0.41	41%	0.412	S	S	.	.	H	α-helix	trans	-56.8	-45.7	-178.7	-69.1	167.4	0	0	0	110.4	Y228 A234 L235 L236	Y228-I232 WeakPolarHBondContact O-CB 2.98Å; Y228-I232 VanDerWaalsContact O-CG1 3.26Å; Y228-I232 WeakPolarHBondContact O-CG1 3.37Å; Y228-I232 PolarHBondContact O-N 2.82Å; I232-A234 VanDerWaalsContact C-N 3.35Å; I232-A234 PolarHBondContact O-N 2.71Å; I232-L235 PolarHBondContact O-N 3.21Å; I232-L236 HydrophobicContact CG2-CD1 3.88Å; I232-L236 HydrophobicContact CG2-CG 4.36Å; I232-L236 WeakPolarHBondContact O-CB 3.49Å; I232-L236 VanDerWaalsContact O-CG 3.27Å; I232-L236 WeakPolarHBondContact O-CG 3.41Å; I232-L236 PolarHBondContact O-N 3.19Å
233	R	83.3	Confident	77.3	Confident	169 Å²	169	81.3 Å²	81.3	64%	0.638	42%	0.423	S	S	*	.	H	α-helix	trans	-60.3	-41.7	175.7	-76.3	178.1	177.1	-174.8	0.4	113	L229 L230 I231 K237	L229-R233 WeakPolarHBondContact O-CB 3.48Å; L229-R233 VanDerWaalsContact O-CG 3.28Å; L229-R233 WeakPolarHBondContact O-CG 3.42Å; L229-R233 PolarHBondContact O-N 2.87Å; L230-R233 PolarHBondContact O-N 3.41Å; I231-R233 VanDerWaalsContact C-N 3.29Å; I231-R233 PolarHBondContact O-N 3.46Å; R233-K237 WeakPolarHBondContact O-CG 3.36Å; R233-K237 PolarHBondContact O-N 2.72Å
234	A	77.3	Confident	76	Confident	24 Å²	24	81.4 Å²	81.4	20%	0.198	43%	0.434	C	S	.	.	H	α-helix	trans	-67	-41.4	177.5	0	0	0	0	0	111.6	V148 L230 I231 I232 L236 K237	V148-A234 HydrophobicContact CB-CB 4.46Å; V148-A234 HydrophobicContact CG1-CB 4.25Å; V148-A234 HydrophobicContact CG2-CB 3.49Å; V148-A234 VanDerWaalsContact CG2-CB 3.49Å; L230-A234 WeakPolarHBondContact O-CB 3.43Å; L230-A234 PolarHBondContact O-N 3.21Å; I231-A234 PolarHBondContact O-N 2.98Å; I232-A234 VanDerWaalsContact C-N 3.35Å; I232-A234 PolarHBondContact O-N 2.71Å; A234-L236 PolarHBondContact O-N 3.16Å; A234-K237 PolarHBondContact O-N 2.96Å
235	L	75.8	Confident	75.2	Confident	30 Å²	30	84.1 Å²	84.1	16%	0.157	45%	0.448	C	S	.	.	H	α-helix	trans	-64.2	-38.4	178.2	-66.9	176.9	0	0	0	112.4	T147 I231 I232 K237 H249 L253	T147-L235 HydrophobicContact CG2-CD2 4.2Å; I231-L235 HydrophobicContact CG2-CD1 3.52Å; I231-L235 HydrophobicContact CG2-CG 3.82Å; I231-L235 WeakPolarHBondContact O-CB 3.38Å; I231-L235 WeakPolarHBondContact O-CG 3.03Å; I231-L235 PolarHBondContact O-N 2.79Å; I232-L235 PolarHBondContact O-N 3.21Å; L235-K237 VanDerWaalsContact C-N 3.27Å; L235-K237 PolarHBondContact O-N 3.28Å; L235-H249 HydrophobicContact CD2-CB 3.64Å; L235-H249 WeakPolarHBondContact CD2-CE1 3.15Å; L235-H249 WeakPolarHBondContact CD2-ND1 3.48Å; L235-L253 HydrophobicContact CD1-CD1 3.86Å; L235-L253 HydrophobicContact CD1-CD2 3.35Å; L235-L253 HydrophobicContact CD1-CG 3.47Å; L235-L253 VanDerWaalsContact CD1-CG 3.47Å
236	L	80.3	Confident	74.5	Confident	145 Å²	145	91 Å²	91	76%	0.759	47%	0.468	S	S	*	.	H	α-helix	trans	-70.9	-19.9	178.1	-70.4	173.1	0	0	0	113.6	I232 A234	I232-L236 HydrophobicContact CG2-CD1 3.88Å; I232-L236 HydrophobicContact CG2-CG 4.36Å; I232-L236 WeakPolarHBondContact O-CB 3.49Å; I232-L236 VanDerWaalsContact O-CG 3.27Å; I232-L236 WeakPolarHBondContact O-CG 3.41Å; I232-L236 PolarHBondContact O-N 3.19Å; A234-L236 PolarHBondContact O-N 3.16Å
237	K	78.2	Confident	73.8	Confident	181 Å²	181	90.1 Å²	90.1	79%	0.787	47%	0.468	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.6	-12.1	-179.8	-78.4	-172.9	176.7	-167.6	0	114.4	R233 A234 L235	R233-K237 WeakPolarHBondContact O-CG 3.36Å; R233-K237 PolarHBondContact O-N 2.72Å; A234-K237 PolarHBondContact O-N 2.96Å; L235-K237 VanDerWaalsContact C-N 3.27Å; L235-K237 PolarHBondContact O-N 3.28Å
238	V	72.3	Confident	73.4	Confident	56 Å²	56	91.2 Å²	91.2	34%	0.339	48%	0.475	S	S	.	.			trans	-94.9	104.8	-176.4	179.7	0	0	0	0	109.3	V240 P241 L245	V238-V240 PolarHBondContact O-N 3.42Å; V238-P241 HydrophobicContact CG1-CB 4.1Å; V238-P241 HydrophobicContact CG1-CG 3.82Å; V238-L245 HydrophobicContact CG1-CD2 4.21Å
239	E	58.3	Low	73.2	Confident	197 Å²	197	91.6 Å²	91.6	92%	0.921	48%	0.478	S	S	*	.	S	Bend	trans	-66.6	-30.8	-172.9	-88.3	175.8	148.7	0	0	114.3
240	V	59.9	Low	73	Confident	130 Å²	130	94 Å²	94	79%	0.788	48%	0.479	S	S	*	.	S	Bend	trans	-153.7	108.4	166.1	-176.3	0	0	0	0	109.2	V238 E242	V238-V240 PolarHBondContact O-N 3.42Å; V240-E242 PolarHBondContact O-N 2.89Å
241	P	61.4	Low	73	Confident	40 Å²	40	92.2 Å²	92.2	26%	0.26	47%	0.469	S	S	.	.			trans	-70.4	132.1	177.8	-13.6	26.1	0	0	0	111.1	V238 L245 R246	V238-P241 HydrophobicContact CG1-CB 4.1Å; V238-P241 HydrophobicContact CG1-CG 3.82Å; P241-L245 HydrophobicContact CB-CB 4.04Å; P241-L245 HydrophobicContact CB-CD2 4.07Å; P241-L245 HydrophobicContact CB-CG 4.08Å; P241-R246 HydrophobicContact CB-CB 4.25Å
242	E	67.2	Low	73.1	Confident	162 Å²	162	92.2 Å²	92.2	76%	0.757	47%	0.469	S	S	*	.			trans	-52.1	156.1	165	-69.5	-164.7	164.1	0	0	111.2	V240 G244 L245 R246	V240-E242 PolarHBondContact O-N 2.89Å; E242-G244 VanDerWaalsContact C-N 3.27Å; E242-G244 PolarHBondContact O-N 3.36Å; E242-G244 VanDerWaalsContact O-N 3.11Å; E242-L245 WeakPolarHBondContact O-CA 3.38Å; E242-L245 WeakPolarHBondContact O-CB 3.36Å; E242-L245 PolarHBondContact O-N 3.49Å; E242-R246 PolarHBondContact O-N 3.22Å
243	S	62.7	Low	73.2	Confident	107 Å²	107	91.7 Å²	91.7	75%	0.748	47%	0.467	S	S	*	.	H	α-helix	trans	-53	-39.5	-171.9	61.9	0	0	0	0	113.9	V247	S243-V247 PolarHBondContact O-N 3.39Å
244	G	62.9	Low	73.4	Confident	51 Å²	51	85 Å²	85	53%	0.526	45%	0.445	S	S	.	.	H	α-helix	trans	-68.8	-40.3	175.3	0	0	0	0	0	113.7	E242 R246 V247 S248	E242-G244 VanDerWaalsContact C-N 3.27Å; E242-G244 PolarHBondContact O-N 3.36Å; E242-G244 VanDerWaalsContact O-N 3.11Å; G244-R246 VanDerWaalsContact C-N 3.35Å; G244-V247 PolarHBondContact O-N 3.47Å; G244-S248 PolarHBondContact O-N 2.98Å
245	L	68.9	Low	73.9	Confident	59 Å²	59	84 Å²	84	31%	0.309	44%	0.436	S	S	.	.	H	α-helix	trans	-67.7	-36.9	178	-169	62.9	0	0	0	111	V238 P241 E242 V247 S248 H249	V238-L245 HydrophobicContact CG1-CD2 4.21Å; P241-L245 HydrophobicContact CB-CB 4.04Å; P241-L245 HydrophobicContact CB-CD2 4.07Å; P241-L245 HydrophobicContact CB-CG 4.08Å; E242-L245 WeakPolarHBondContact O-CA 3.38Å; E242-L245 WeakPolarHBondContact O-CB 3.36Å; E242-L245 PolarHBondContact O-N 3.49Å; L245-V247 VanDerWaalsContact C-N 3.35Å; L245-V247 PolarHBondContact O-N 3.35Å; L245-S248 PolarHBondContact O-N 3.49Å; L245-H249 WeakPolarHBondContact CG-NE2 3.35Å; L245-H249 WeakPolarHBondContact O-CB 3.35Å; L245-H249 PolarHBondContact O-CD2 3.18Å; L245-H249 PolarHBondContact O-N 2.72Å
246	R	72.9	Confident	74.4	Confident	181 Å²	181	83 Å²	83	68%	0.683	43%	0.43	S	S	*	.	H	α-helix	trans	-60.6	-39.5	174.7	-168.6	176	178.3	-172.3	0.4	112.9	P241 E242 G244 R250	P241-R246 HydrophobicContact CB-CB 4.25Å; E242-R246 PolarHBondContact O-N 3.22Å; G244-R246 VanDerWaalsContact C-N 3.35Å; R246-R250 WeakPolarHBondContact O-CB 3.38Å; R246-R250 PolarHBondContact O-N 3.12Å
247	V	74.1	Confident	74.8	Confident	84 Å²	84	80.6 Å²	80.6	51%	0.509	42%	0.417	S	S	.	.	H	α-helix	trans	-68.4	-43.7	176.5	174.9	0	0	0	0	111	S243 G244 L245 R250 K251	S243-V247 PolarHBondContact O-N 3.39Å; G244-V247 PolarHBondContact O-N 3.47Å; L245-V247 VanDerWaalsContact C-N 3.35Å; L245-V247 PolarHBondContact O-N 3.35Å; V247-R250 PolarHBondContact O-N 3.36Å; V247-K251 WeakPolarHBondContact O-CG 3.12Å; V247-K251 PolarHBondContact O-N 2.82Å
248	S	74.3	Confident	75.4	Confident	34 Å²	34	73 Å²	73	24%	0.238	39%	0.385	C	S	.	.	H	α-helix	trans	-59.7	-47.6	175.1	-170.1	0	0	0	0	111.3	G244 L245 R250 K251 A252	G244-S248 PolarHBondContact O-N 2.98Å; L245-S248 PolarHBondContact O-N 3.49Å; S248-R250 PolarHBondContact O-N 3.05Å; S248-K251 PolarHBondContact O-N 3.27Å; S248-A252 WeakPolarHBondContact O-CB 3.24Å; S248-A252 PolarHBondContact O-N 3.03Å
249	H	78.8	Confident	76.3	Confident	19 Å²	19	70.3 Å²	70.3	9%	0.088	37%	0.369	C	S	.	.	H	α-helix	trans	-56.5	-47.8	176.6	-75.3	-156.9	0	0	0	111.9	T147 L235 L245 K251 A252 L253	T147-H249 VanDerWaalsContact CG2-CD2 3.5Å; T147-H249 WeakPolarHBondContact CG2-CD2 3.28Å; L235-H249 HydrophobicContact CD2-CB 3.64Å; L235-H249 WeakPolarHBondContact CD2-CE1 3.15Å; L235-H249 WeakPolarHBondContact CD2-ND1 3.48Å; L245-H249 WeakPolarHBondContact CG-NE2 3.35Å; L245-H249 WeakPolarHBondContact O-CB 3.35Å; L245-H249 PolarHBondContact O-CD2 3.18Å; L245-H249 PolarHBondContact O-N 2.72Å; H249-K251 PolarHBondContact O-N 3.39Å; H249-A252 PolarHBondContact O-N 2.83Å; H249-L253 WeakPolarHBondContact O-CB 3.3Å; H249-L253 WeakPolarHBondContact O-CG 3.46Å; H249-L253 PolarHBondContact O-N 2.81Å
250	R	81.9	Confident	77.8	Confident	153 Å²	153	63.2 Å²	63.2	58%	0.577	34%	0.337	S	S	*	.	H	α-helix	trans	-61.5	-43.8	178.2	-178.8	176.1	174.8	-87.7	-2.6	111.9	R246 V247 S248 T254	R246-R250 WeakPolarHBondContact O-CB 3.38Å; R246-R250 PolarHBondContact O-N 3.12Å; V247-R250 PolarHBondContact O-N 3.36Å; S248-R250 PolarHBondContact O-N 3.05Å; R250-T254 WeakPolarHBondContact O-CB 3.29Å; R250-T254 PolarHBondContact O-N 3.48Å; R250-T254 PolarHBondContact O-OG1 2.98Å
251	K	82.1	Confident	79.3	Confident	34 Å²	34	61.5 Å²	61.5	15%	0.148	32%	0.322	C	S	.	.	H	α-helix	trans	-66.4	-40	177.7	-72	-172.6	-174.7	-167.2	0	112	V247 S248 H249 T254 T255 G316 E317	V247-K251 WeakPolarHBondContact O-CG 3.12Å; V247-K251 PolarHBondContact O-N 2.82Å; S248-K251 PolarHBondContact O-N 3.27Å; H249-K251 PolarHBondContact O-N 3.39Å; K251-T254 PolarHBondContact O-N 3.07Å; K251-T255 WeakPolarHBondContact O-CB 3.08Å; K251-T255 PolarHBondContact O-N 2.89Å; K251-T255 PolarHBondContact O-OG1 3.2Å; K251-G316 PolarHBondContact NZ-O 2.88Å; K251-E317 VanDerWaalsContact CD-OE1 3.27Å; K251-E317 WeakPolarHBondContact CD-OE1 3.46Å; K251-E317 IonicContact NZ-OE1 3.06Å; K251-E317 PolarHBondContact NZ-OE1 3.29Å; K251-E317 IonicContact NZ-OE2 2.73Å; K251-E317 PolarHBondContact NZ-OE2 3.29Å
252	A	81.8	Confident	80.9	Confident	1 Å²	1	59.7 Å²	59.7	1%	0.008	31%	0.311	C	S	.	.	H	α-helix	trans	-60.1	-56.8	174.2	0	0	0	0	0	110.2	T147 S248 H249 T254 T255 I256	T147-A252 WeakPolarHBondContact OG1-CB 3.34Å; S248-A252 WeakPolarHBondContact O-CB 3.24Å; S248-A252 PolarHBondContact O-N 3.03Å; H249-A252 PolarHBondContact O-N 2.83Å; A252-T254 VanDerWaalsContact C-N 3.28Å; A252-T254 PolarHBondContact O-N 3.26Å; A252-T255 WeakPolarHBondContact O-CA 3.11Å; A252-T255 VanDerWaalsContact O-CB 3.3Å; A252-T255 WeakPolarHBondContact O-CB 3.35Å; A252-T255 PolarHBondContact O-N 3.47Å; A252-I256 VanDerWaalsContact O-CG1 3.29Å; A252-I256 WeakPolarHBondContact O-CG1 3.3Å; A252-I256 PolarHBondContact O-N 3.27Å
253	L	83.8	Confident	82.1	Confident	69 Å²	69	52 Å²	52	36%	0.361	28%	0.275	S	S	.	.	H	α-helix	trans	-53.5	-43.1	176.4	-77.8	174	0	0	0	113.1	L235 H249 T255 I256 I257	L235-L253 HydrophobicContact CD1-CD1 3.86Å; L235-L253 HydrophobicContact CD1-CD2 3.35Å; L235-L253 HydrophobicContact CD1-CG 3.47Å; L235-L253 VanDerWaalsContact CD1-CG 3.47Å; H249-L253 WeakPolarHBondContact O-CB 3.3Å; H249-L253 WeakPolarHBondContact O-CG 3.46Å; H249-L253 PolarHBondContact O-N 2.81Å; L253-T255 PolarHBondContact O-N 3.42Å; L253-I256 HydrophobicContact CD2-CD1 4.33Å; L253-I256 WeakPolarHBondContact O-CB 3.42Å; L253-I256 PolarHBondContact O-N 3.48Å; L253-I257 VanDerWaalsContact O-CG1 3.31Å; L253-I257 WeakPolarHBondContact O-CG1 3.22Å; L253-I257 PolarHBondContact O-N 3.26Å
254	T	87.2	Confident	83.6	Confident	29 Å²	29	52 Å²	52	18%	0.178	26%	0.261	C	S	.	.	H	α-helix	trans	-65.6	-40.1	178.6	-53.3	0	0	0	0	111.6	R250 K251 A252 I256 I257 I258 F314	R250-T254 WeakPolarHBondContact O-CB 3.29Å; R250-T254 PolarHBondContact O-N 3.48Å; R250-T254 PolarHBondContact O-OG1 2.98Å; K251-T254 PolarHBondContact O-N 3.07Å; A252-T254 VanDerWaalsContact C-N 3.28Å; A252-T254 PolarHBondContact O-N 3.26Å; T254-I256 VanDerWaalsContact C-N 3.35Å; T254-I257 PolarHBondContact O-N 3.46Å; T254-I258 HydrophobicContact CG2-CD1 3.71Å; T254-I258 HydrophobicContact CG2-CG1 4.36Å; T254-I258 WeakPolarHBondContact O-CB 3.22Å; T254-I258 VanDerWaalsContact O-CG1 3.31Å; T254-I258 WeakPolarHBondContact O-CG1 3.25Å; T254-I258 PolarHBondContact O-N 3.25Å; T254-F314 HydrophobicContact CG2-CB 3.66Å
255	T	87	Confident	85.1	Confident	1 Å²	1	53.1 Å²	53.1	1%	0.006	26%	0.255	C	S	.	.	H	α-helix	trans	-59.3	-46.9	172.7	-55.5	0	0	0	0	110.6	L139 R143 K251 A252 L253 T259 L311 A315	L139-T255 HydrophobicContact CD2-CG2 4.38Å; L139-T255 HydrophobicContact CG-CG2 4.23Å; R143-T255 HydrophobicContact CG-CG2 4.07Å; K251-T255 WeakPolarHBondContact O-CB 3.08Å; K251-T255 PolarHBondContact O-N 2.89Å; K251-T255 PolarHBondContact O-OG1 3.2Å; A252-T255 WeakPolarHBondContact O-CA 3.11Å; A252-T255 VanDerWaalsContact O-CB 3.3Å; A252-T255 WeakPolarHBondContact O-CB 3.35Å; A252-T255 PolarHBondContact O-N 3.47Å; L253-T255 PolarHBondContact O-N 3.42Å; T255-T259 VanDerWaalsContact O-CB 3.23Å; T255-T259 WeakPolarHBondContact O-CB 3.28Å; T255-T259 PolarHBondContact O-N 2.92Å; T255-T259 PolarHBondContact O-OG1 3.16Å; T255-L311 HydrophobicContact CG2-CD1 4.06Å; T255-A315 VanDerWaalsContact OG1-CB 3.29Å; T255-A315 WeakPolarHBondContact OG1-CB 3.3Å
256	I	86.2	Confident	86.4	Confident	9 Å²	9	50.3 Å²	50.3	5%	0.046	24%	0.24	C	C	.	.	H	α-helix	trans	-57.1	-53.8	178.5	-60.8	173.6	0	0	0	110.7	Y228 I231 A252 L253 T254 T259 L260	Y228-I256 HydrophobicContact CD1-CB 3.9Å; Y228-I256 HydrophobicContact CD1-CD1 3.88Å; Y228-I256 HydrophobicContact CD1-CG1 3.41Å; Y228-I256 VanDerWaalsContact CD1-CG1 3.41Å; Y228-I256 HydrophobicContact CD1-CG2 3.5Å; Y228-I256 VanDerWaalsContact CD1-CG2 3.5Å; Y228-I256 HydrophobicContact CD2-CG2 3.72Å; Y228-I256 HydrophobicContact CE1-CB 3.76Å; Y228-I256 HydrophobicContact CE1-CD1 4.4Å; Y228-I256 HydrophobicContact CE1-CG1 3.45Å; Y228-I256 VanDerWaalsContact CE1-CG1 3.45Å; Y228-I256 HydrophobicContact CE1-CG2 3.68Å; Y228-I256 HydrophobicContact CE2-CG2 3.91Å; Y228-I256 HydrophobicContact CG-CB 4.39Å; Y228-I256 HydrophobicContact CG-CG1 4.25Å; Y228-I256 HydrophobicContact CG-CG2 3.48Å; Y228-I256 VanDerWaalsContact CG-CG2 3.48Å; I231-I256 HydrophobicContact CB-CD1 3.82Å; I231-I256 HydrophobicContact CD1-CD1 3.41Å; I231-I256 VanDerWaalsContact CD1-CD1 3.41Å; I231-I256 HydrophobicContact CD1-CG1 3.81Å; I231-I256 HydrophobicContact CG1-CD1 4.2Å; I231-I256 HydrophobicContact CG2-CD1 3.62Å; A252-I256 VanDerWaalsContact O-CG1 3.29Å; A252-I256 WeakPolarHBondContact O-CG1 3.3Å; A252-I256 PolarHBondContact O-N 3.27Å; L253-I256 HydrophobicContact CD2-CD1 4.33Å; L253-I256 WeakPolarHBondContact O-CB 3.42Å; L253-I256 PolarHBondContact O-N 3.48Å; T254-I256 VanDerWaalsContact C-N 3.35Å; I256-T259 PolarHBondContact O-N 2.87Å; I256-L260 HydrophobicContact CG2-CD1 3.81Å; I256-L260 HydrophobicContact CG2-CG 4.29Å; I256-L260 WeakPolarHBondContact O-CB 3.46Å; I256-L260 WeakPolarHBondContact O-CG 3.43Å; I256-L260 PolarHBondContact O-N 2.9Å
257	I	88.3	Confident	87.4	Confident	95 Å²	95	41.7 Å²	41.7	49%	0.487	21%	0.208	S	C	.	.	H	α-helix	trans	-61.5	-49.6	-174.6	-69.8	163.7	0	0	0	110.4	L253 T254 L260 I261	L253-I257 VanDerWaalsContact O-CG1 3.31Å; L253-I257 WeakPolarHBondContact O-CG1 3.22Å; L253-I257 PolarHBondContact O-N 3.26Å; T254-I257 PolarHBondContact O-N 3.46Å; I257-L260 PolarHBondContact O-N 3.45Å; I257-I261 HydrophobicContact CG2-CD1 3.83Å; I257-I261 VanDerWaalsContact O-CG1 3.27Å; I257-I261 WeakPolarHBondContact O-CG1 3.33Å; I257-I261 PolarHBondContact O-N 2.85Å
258	I	91.9	Very high	88.4	Confident	21 Å²	21	40.1 Å²	40.1	11%	0.108	20%	0.196	C	C	.	.	H	α-helix	trans	-63.4	-46.7	-179.1	-66.1	172.4	0	0	0	110.4	T254 L260 I261 I262 L311 F314	T254-I258 HydrophobicContact CG2-CD1 3.71Å; T254-I258 HydrophobicContact CG2-CG1 4.36Å; T254-I258 WeakPolarHBondContact O-CB 3.22Å; T254-I258 VanDerWaalsContact O-CG1 3.31Å; T254-I258 WeakPolarHBondContact O-CG1 3.25Å; T254-I258 PolarHBondContact O-N 3.25Å; I258-L260 PolarHBondContact O-N 2.93Å; I258-I261 PolarHBondContact O-N 2.81Å; I258-I262 HydrophobicContact CG2-CD1 3.94Å; I258-I262 WeakPolarHBondContact O-CG1 3.34Å; I258-I262 PolarHBondContact O-N 3.49Å; I258-L311 HydrophobicContact CB-CD1 4.19Å; I258-L311 HydrophobicContact CD1-CD1 4.44Å; I258-L311 HydrophobicContact CG2-CB 4.01Å; I258-L311 HydrophobicContact CG2-CD1 4.16Å; I258-F314 HydrophobicContact CD1-CB 4.16Å; I258-F314 HydrophobicContact CD1-CD2 4.33Å
259	T	91.1	Very high	89.5	Confident	0 Å²	0	40.3 Å²	40.3	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-63.3	-40.9	178.7	-61.6	0	0	0	0	111.5	L136 L224 Y228 T255 I256 I261 I262 F263	L136-T259 HydrophobicContact CB-CG2 4Å; L224-T259 HydrophobicContact CD1-CG2 3.82Å; L224-T259 HydrophobicContact CD2-CG2 4.45Å; Y228-T259 WeakPolarHBondContact OH-CB 3.47Å; Y228-T259 WeakPolarHBondContact OH-CG2 3.38Å; T255-T259 VanDerWaalsContact O-CB 3.23Å; T255-T259 WeakPolarHBondContact O-CB 3.28Å; T255-T259 PolarHBondContact O-N 2.92Å; T255-T259 PolarHBondContact O-OG1 3.16Å; I256-T259 PolarHBondContact O-N 2.87Å; T259-I261 PolarHBondContact O-N 3.43Å; T259-I262 PolarHBondContact O-N 3.11Å; T259-F263 HydrophobicContact CG2-CD2 3.75Å; T259-F263 HydrophobicContact CG2-CE2 3.72Å; T259-F263 VanDerWaalsContact O-CD2 3.27Å; T259-F263 WeakPolarHBondContact O-CD2 3.4Å; T259-F263 PolarHBondContact O-N 3.2Å
260	L	90.3	Very high	90.3	Very high	48 Å²	48	39.7 Å²	39.7	25%	0.251	19%	0.193	S	C	.	.	H	α-helix	trans	-61.1	-44.5	175.1	-79.8	177.6	0	0	0	112.2	Y228 I256 I257 I258 I262 F263 F264	Y228-L260 HydrophobicContact CD2-CD1 3.85Å; Y228-L260 HydrophobicContact CD2-CD2 3.62Å; Y228-L260 HydrophobicContact CD2-CG 3.72Å; Y228-L260 HydrophobicContact CE2-CD1 4.01Å; Y228-L260 HydrophobicContact CE2-CD2 3.35Å; Y228-L260 HydrophobicContact CE2-CG 3.36Å; I256-L260 HydrophobicContact CG2-CD1 3.81Å; I256-L260 HydrophobicContact CG2-CG 4.29Å; I256-L260 WeakPolarHBondContact O-CB 3.46Å; I256-L260 WeakPolarHBondContact O-CG 3.43Å; I256-L260 PolarHBondContact O-N 2.9Å; I257-L260 PolarHBondContact O-N 3.45Å; I258-L260 PolarHBondContact O-N 2.93Å; L260-I262 VanDerWaalsContact C-N 3.29Å; L260-I262 PolarHBondContact O-N 3.27Å; L260-F263 PolarHBondContact O-N 3.39Å; L260-F264 HydrophobicContact CB-CD2 4.32Å; L260-F264 HydrophobicContact CD2-CD2 4.29Å; L260-F264 HydrophobicContact CD2-CE2 3.8Å; L260-F264 WeakPolarHBondContact O-CB 3.2Å; L260-F264 VanDerWaalsContact O-CD2 3.25Å; L260-F264 WeakPolarHBondContact O-CD2 3.41Å; L260-F264 PolarHBondContact O-N 3.48Å
261	I	91.6	Very high	90.9	Very high	94 Å²	94	32.4 Å²	32.4	48%	0.482	17%	0.166	S	C	.	.	H	α-helix	trans	-57.6	-46.8	176	-69.7	165.3	0	0	0	109.7	I257 I258 T259 F263 F264 L265	I257-I261 HydrophobicContact CG2-CD1 3.83Å; I257-I261 VanDerWaalsContact O-CG1 3.27Å; I257-I261 WeakPolarHBondContact O-CG1 3.33Å; I257-I261 PolarHBondContact O-N 2.85Å; I258-I261 PolarHBondContact O-N 2.81Å; T259-I261 PolarHBondContact O-N 3.43Å; I261-F263 PolarHBondContact O-N 2.85Å; I261-F264 PolarHBondContact O-N 3.08Å; I261-L265 WeakPolarHBondContact O-CB 3.41Å; I261-L265 PolarHBondContact O-N 2.99Å
262	I	93.9	Very high	91.5	Very high	2 Å²	2	34.4 Å²	34.4	1%	0.01	18%	0.181	C	C	.	.	H	α-helix	trans	-60	-46.6	177.7	-67	165.9	0	0	0	111.1	L136 I258 T259 L260 C266 F267 N304 F307 N308	L136-I262 HydrophobicContact CD1-CD1 4.43Å; L136-I262 HydrophobicContact CD1-CG2 3.96Å; I258-I262 HydrophobicContact CG2-CD1 3.94Å; I258-I262 WeakPolarHBondContact O-CG1 3.34Å; I258-I262 PolarHBondContact O-N 3.49Å; T259-I262 PolarHBondContact O-N 3.11Å; L260-I262 VanDerWaalsContact C-N 3.29Å; L260-I262 PolarHBondContact O-N 3.27Å; I262-C266 HydrophobicContact CG2-CB 4.41Å; I262-C266 WeakPolarHBondContact O-CA 3.31Å; I262-C266 WeakPolarHBondContact O-CB 3.21Å; I262-C266 PolarHBondContact O-N 3.01Å; I262-F267 HydrophobicContact CG2-CD2 4.21Å; I262-F267 HydrophobicContact CG2-CE2 3.66Å; I262-F267 HydrophobicContact CG2-CZ 4.16Å; I262-N304 HydrophobicContact CG2-CB 4.24Å; I262-F307 HydrophobicContact CD1-CB 4.18Å; I262-F307 HydrophobicContact CG1-CB 3.98Å; I262-N308 WeakPolarHBondContact CD1-OD1 3.41Å
263	F	92.9	Very high	92.1	Very high	1 Å²	1	36.3 Å²	36.3	0%	0.004	19%	0.191	C	C	.	.	I	π-helix	trans	-64	-46.8	-179.8	-90.6	-105	0	0	0	112.7	I133 L136 F217 P220 F221 L224 T259 L260 I261 F267 L268	I133-F263 HydrophobicContact CB-CZ 4.4Å; I133-F263 HydrophobicContact CG1-CZ 4.41Å; I133-F263 HydrophobicContact CG2-CE1 4.09Å; I133-F263 HydrophobicContact CG2-CZ 3.83Å; L136-F263 HydrophobicContact CB-CE2 4.12Å; L136-F263 HydrophobicContact CD1-CE2 4.11Å; F217-F263 AromaticContact CE2-CD1 3.96Å; F217-F263 HydrophobicContact CE2-CD1 3.96Å; F217-F263 HydrophobicContact CE2-CE1 4.45Å; P220-F263 HydrophobicContact CB-CE1 4.34Å; P220-F263 HydrophobicContact CB-CZ 4.47Å; F221-F263 HydrophobicContact CD2-CD1 4.23Å; L224-F263 HydrophobicContact CD1-CD1 4.16Å; L224-F263 HydrophobicContact CD1-CD2 3.73Å; L224-F263 HydrophobicContact CD1-CE1 3.76Å; L224-F263 HydrophobicContact CD1-CE2 3.28Å; L224-F263 HydrophobicContact CD1-CG 4.13Å; L224-F263 HydrophobicContact CD1-CZ 3.27Å; L224-F263 HydrophobicContact CG-CZ 4.48Å; T259-F263 HydrophobicContact CG2-CD2 3.75Å; T259-F263 HydrophobicContact CG2-CE2 3.72Å; T259-F263 VanDerWaalsContact O-CD2 3.27Å; T259-F263 WeakPolarHBondContact O-CD2 3.4Å; T259-F263 PolarHBondContact O-N 3.2Å; L260-F263 PolarHBondContact O-N 3.39Å; I261-F263 PolarHBondContact O-N 2.85Å; F263-F267 HydrophobicContact CD1-CD2 4.32Å; F263-F267 HydrophobicContact CD2-CD2 4.18Å; F263-F267 HydrophobicContact CE2-CD2 4.38Å; F263-F267 HydrophobicContact CE2-CE2 4.49Å; F263-F267 HydrophobicContact CG-CD2 4.18Å; F263-F267 PolarHBondContact O-N 2.93Å; F263-L268 WeakPolarHBondContact O-CB 3.41Å; F263-L268 PolarHBondContact O-N 2.81Å
264	F	93.4	Very high	92.5	Very high	106 Å²	106	33.9 Å²	33.9	47%	0.465	18%	0.177	S	C	.	.	I	π-helix	trans	-74	-32	-177.7	-77.2	-63	0	0	0	113.3	F221 L260 I261 L268 P269	F221-F264 AromaticContact CE2-CE1 3.95Å; F221-F264 HydrophobicContact CE2-CE1 3.95Å; F221-F264 AromaticContact CE2-CZ 3.92Å; F221-F264 HydrophobicContact CE2-CZ 3.92Å; F221-F264 HydrophobicContact CZ-CE1 4.13Å; F221-F264 HydrophobicContact CZ-CZ 4.07Å; L260-F264 HydrophobicContact CB-CD2 4.32Å; L260-F264 HydrophobicContact CD2-CD2 4.29Å; L260-F264 HydrophobicContact CD2-CE2 3.8Å; L260-F264 WeakPolarHBondContact O-CB 3.2Å; L260-F264 VanDerWaalsContact O-CD2 3.25Å; L260-F264 WeakPolarHBondContact O-CD2 3.41Å; L260-F264 PolarHBondContact O-N 3.48Å; I261-F264 PolarHBondContact O-N 3.08Å; F264-L268 HydrophobicContact CD1-CD2 3.62Å; F264-L268 HydrophobicContact CE1-CD2 3.93Å; F264-P269 WeakPolarHBondContact O-CD 3.44Å; F264-P269 VanDerWaalsContact O-CG 3.22Å; F264-P269 WeakPolarHBondContact O-CG 3.5Å
265	L	94.7	Very high	92.8	Very high	75 Å²	75	33.6 Å²	33.6	39%	0.393	18%	0.175	S	C	.	.	I	π-helix	trans	-87.6	-42.3	-178.9	-174.5	62.1	0	0	0	112.6	I261 F307	I261-L265 WeakPolarHBondContact O-CB 3.41Å; I261-L265 PolarHBondContact O-N 2.99Å; L265-F307 HydrophobicContact CD2-CE2 4.32Å; L265-F307 HydrophobicContact CD2-CZ 4.29Å
266	C	95.7	Very high	93	Very high	0 Å²	0	37.5 Å²	37.5	0%	0	20%	0.196	C	C	.	.	I	π-helix	trans	-99.9	-45.4	-168.6	-51.6	0	0	0	0	112.5	I262 L300 A301 N304	I262-C266 HydrophobicContact CG2-CB 4.41Å; I262-C266 WeakPolarHBondContact O-CA 3.31Å; I262-C266 WeakPolarHBondContact O-CB 3.21Å; I262-C266 PolarHBondContact O-N 3.01Å; C266-L300 WeakPolarHBondContact CB-O 3.32Å; C266-A301 WeakPolarHBondContact O-CA 3.46Å; C266-A301 WeakPolarHBondContact O-CB 3.4Å; C266-N304 HydrophobicContact CB-CB 3.93Å
267	F	95.6	Very high	93.1	Very high	0 Å²	0	38.4 Å²	38.4	0%	0	20%	0.2	C	C	.	.	I	π-helix	trans	-97.2	-48.2	-168.8	-59.7	-42	0	0	0	113.9	M129 I133 L136 F217 I262 F263 Y270 H271 N304	M129-F267 HydrophobicContact CG-CD1 4.09Å; M129-F267 HydrophobicContact CG-CE1 3.9Å; I133-F267 HydrophobicContact CD1-CD1 4.2Å; I133-F267 HydrophobicContact CD1-CD2 4.09Å; I133-F267 HydrophobicContact CD1-CE1 4.46Å; I133-F267 HydrophobicContact CD1-CE2 4.33Å; I133-F267 HydrophobicContact CD1-CG 4.03Å; I133-F267 HydrophobicContact CG1-CD1 4.34Å; I133-F267 HydrophobicContact CG1-CD2 3.57Å; I133-F267 HydrophobicContact CG1-CE1 4.27Å; I133-F267 HydrophobicContact CG1-CE2 3.47Å; I133-F267 VanDerWaalsContact CG1-CE2 3.47Å; I133-F267 HydrophobicContact CG1-CG 4.03Å; I133-F267 HydrophobicContact CG1-CZ 3.85Å; L136-F267 HydrophobicContact CD1-CE2 4.19Å; F217-F267 HydrophobicContact CD2-CB 3.99Å; F217-F267 HydrophobicContact CE2-CB 3.69Å; I262-F267 HydrophobicContact CG2-CD2 4.21Å; I262-F267 HydrophobicContact CG2-CE2 3.66Å; I262-F267 HydrophobicContact CG2-CZ 4.16Å; F263-F267 HydrophobicContact CD1-CD2 4.32Å; F263-F267 HydrophobicContact CD2-CD2 4.18Å; F263-F267 HydrophobicContact CE2-CD2 4.38Å; F263-F267 HydrophobicContact CE2-CE2 4.49Å; F263-F267 HydrophobicContact CG-CD2 4.18Å; F263-F267 PolarHBondContact O-N 2.93Å; F267-Y270 PolarHBondContact O-N 3.47Å; F267-H271 PolarHBondContact O-CD2 3.18Å; F267-H271 VanDerWaalsContact O-CD2 3.26Å; F267-H271 PolarHBondContact O-N 3.23Å; F267-N304 HydrophobicContact CE1-CB 3.97Å; F267-N304 HydrophobicContact CZ-CB 3.86Å
268	L	94.8	Very high	93	Very high	52 Å²	52	34.1 Å²	34.1	27%	0.272	18%	0.178	S	C	.	.	H	α-helix	trans	-57.4	-50.3	-177.8	179.9	66.3	0	0	0	112.2	F217 F263 F264 Y270 H271 T272	F217-L268 HydrophobicContact CE1-CD1 3.59Å; F217-L268 HydrophobicContact CE2-CB 4.38Å; F217-L268 HydrophobicContact CZ-CB 3.72Å; F217-L268 HydrophobicContact CZ-CD1 3.55Å; F217-L268 HydrophobicContact CZ-CG 4.24Å; F263-L268 WeakPolarHBondContact O-CB 3.41Å; F263-L268 PolarHBondContact O-N 2.81Å; F264-L268 HydrophobicContact CD1-CD2 3.62Å; F264-L268 HydrophobicContact CE1-CD2 3.93Å; L268-Y270 VanDerWaalsContact C-N 3.26Å; L268-Y270 PolarHBondContact O-N 3.42Å; L268-H271 PolarHBondContact O-N 2.86Å; L268-T272 WeakPolarHBondContact O-CB 3.3Å; L268-T272 PolarHBondContact O-N 3.45Å; L268-T272 PolarHBondContact O-OG1 3.12Å; L268-T272 VanDerWaalsContact O-OG1 3.08Å
269	P	96.5	Very high	92.7	Very high	37 Å²	37	36.8 Å²	36.8	24%	0.24	20%	0.195	C	C	.	.	H	α-helix	trans	-62.9	-36.7	-177.3	-22.5	36.8	0	0	0	111.8	F264 L273 T297	F264-P269 WeakPolarHBondContact O-CD 3.44Å; F264-P269 VanDerWaalsContact O-CG 3.22Å; F264-P269 WeakPolarHBondContact O-CG 3.5Å; P269-L273 WeakPolarHBondContact O-CB 3.03Å; P269-L273 VanDerWaalsContact O-CG 3.28Å; P269-L273 WeakPolarHBondContact O-CG 3.05Å; P269-L273 PolarHBondContact O-N 3.22Å; P269-T297 HydrophobicContact CB-CG2 3.49Å; P269-T297 VanDerWaalsContact CB-CG2 3.49Å
270	Y	96.1	Very high	92.5	Very high	6 Å²	6	38.5 Å²	38.5	2%	0.024	21%	0.205	C	C	.	.	H	α-helix	trans	-66.2	-52.6	177.3	173.5	-113.5	0	0	0	111.8	Y126 M129 F267 L268 T272 L273 R274 L298 A301	Y126-Y270 PolarHBondContact OH-OH 2.94Å; Y126-Y270 VanDerWaalsContact OH-OH 3.07Å; M129-Y270 HydrophobicContact CE-CE1 4.03Å; M129-Y270 HydrophobicContact SD-CD1 3.79Å; M129-Y270 HydrophobicContact SD-CE1 3.57Å; M129-Y270 VanDerWaalsContact SD-CE1 3.57Å; F267-Y270 PolarHBondContact O-N 3.47Å; L268-Y270 VanDerWaalsContact C-N 3.26Å; L268-Y270 PolarHBondContact O-N 3.42Å; Y270-T272 VanDerWaalsContact C-N 3.34Å; Y270-T272 PolarHBondContact O-N 2.96Å; Y270-L273 PolarHBondContact O-N 3.31Å; Y270-R274 HydrophobicContact CE2-CB 4.31Å; Y270-R274 WeakPolarHBondContact O-CB 3.46Å; Y270-R274 PolarHBondContact O-N 3.37Å; Y270-R274 WeakPolarHBondContact OH-CD 3.45Å; Y270-R274 PolarHBondContact OH-NE 2.71Å; Y270-L298 HydrophobicContact CD2-CB 3.97Å; Y270-L298 HydrophobicContact CD2-CD1 4.26Å; Y270-L298 HydrophobicContact CE2-CB 3.87Å; Y270-L298 HydrophobicContact CE2-CD1 3.61Å; Y270-L298 HydrophobicContact CE2-CG 4.28Å; Y270-A301 HydrophobicContact CD1-CB 4.23Å; Y270-A301 HydrophobicContact CG-CB 4.04Å
271	H	95.2	Very high	92	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-62.9	-39.7	-178.4	-80.1	-69.5	0	0	0	112.8	M129 Y130 L213 F217 F267 L268 T275	M129-H271 VanDerWaalsContact CE-CE1 3.46Å; M129-H271 WeakPolarHBondContact CE-CE1 3.47Å; M129-H271 WeakPolarHBondContact CE-NE2 3.33Å; Y130-H271 AromaticContact CE1-CE1 4Å; L213-H271 HydrophobicContact CD1-CB 3.91Å; F217-H271 HydrophobicContact CD1-CB 4.17Å; F217-H271 AromaticContact CD2-CD2 3.45Å; F217-H271 VanDerWaalsContact CD2-CD2 3.45Å; F217-H271 WeakPolarHBondContact CD2-CD2 3.4Å; F217-H271 HydrophobicContact CG-CB 4.25Å; F217-H271 AromaticContact CG-CD2 3.52Å; F217-H271 AromaticContact CG-CG 3.88Å; F267-H271 PolarHBondContact O-CD2 3.18Å; F267-H271 VanDerWaalsContact O-CD2 3.26Å; F267-H271 PolarHBondContact O-N 3.23Å; L268-H271 PolarHBondContact O-N 2.86Å; H271-T275 VanDerWaalsContact O-CB 3.31Å; H271-T275 WeakPolarHBondContact O-CB 3.25Å; H271-T275 PolarHBondContact O-N 3.24Å; H271-T275 VanDerWaalsContact O-N 3.1Å; H271-T275 PolarHBondContact O-OG1 3.25Å
272	T	94.6	Very high	91.3	Very high	77 Å²	77	41.9 Å²	41.9	47%	0.472	21%	0.212	S	C	.	.	H	α-helix	trans	-64.6	-53.3	176.2	-59.9	0	0	0	0	111.3	L268 Y270 T275 L276	L268-T272 WeakPolarHBondContact O-CB 3.3Å; L268-T272 PolarHBondContact O-N 3.45Å; L268-T272 PolarHBondContact O-OG1 3.12Å; L268-T272 VanDerWaalsContact O-OG1 3.08Å; Y270-T272 VanDerWaalsContact C-N 3.34Å; Y270-T272 PolarHBondContact O-N 2.96Å; T272-T275 PolarHBondContact O-N 3.12Å; T272-L276 WeakPolarHBondContact O-CB 3.48Å; T272-L276 PolarHBondContact O-N 2.98Å
273	L	94.5	Very high	90	Very high	40 Å²	40	45.9 Å²	45.9	21%	0.209	24%	0.237	C	C	.	.	H	α-helix	trans	-70.8	-35.3	-176.4	-66.6	-175	0	0	0	112.6	P269 Y270 L276 H277 L290 A293 V294 T297	P269-L273 WeakPolarHBondContact O-CB 3.03Å; P269-L273 VanDerWaalsContact O-CG 3.28Å; P269-L273 WeakPolarHBondContact O-CG 3.05Å; P269-L273 PolarHBondContact O-N 3.22Å; Y270-L273 PolarHBondContact O-N 3.31Å; L273-L276 PolarHBondContact O-N 3.38Å; L273-H277 WeakPolarHBondContact O-CB 3.31Å; L273-H277 PolarHBondContact O-N 3.47Å; L273-L290 HydrophobicContact CD2-CD1 4.13Å; L273-A293 HydrophobicContact CD1-CB 3.62Å; L273-V294 HydrophobicContact CB-CG2 3.8Å; L273-V294 WeakPolarHBondContact O-CG2 3.17Å; L273-T297 HydrophobicContact CD1-CG2 3.62Å
274	R	92	Very high	88.6	Confident	19 Å²	19	52.9 Å²	52.9	7%	0.072	28%	0.275	C	S	.	.	H	α-helix	trans	-61.2	-45.3	173.5	-178.5	-179.3	-170.6	-102.1	-0.8	111.1	Y126 N209 Y270 H277 L278	Y126-R274 PolarHBondContact OH-NE 2.95Å; Y126-R274 PolarHBondContact OH-NH2 3.45Å; Y126-R274 VanDerWaalsContact OH-NH2 3.11Å; N209-R274 VanDerWaalsContact CG-NH1 3.3Å; N209-R274 PolarHBondContact OD1-NH1 3.08Å; Y270-R274 HydrophobicContact CE2-CB 4.31Å; Y270-R274 WeakPolarHBondContact O-CB 3.46Å; Y270-R274 PolarHBondContact O-N 3.37Å; Y270-R274 WeakPolarHBondContact OH-CD 3.45Å; Y270-R274 PolarHBondContact OH-NE 2.71Å; R274-H277 PolarHBondContact O-N 3.13Å; R274-L278 HydrophobicContact CG-CD1 4.07Å; R274-L278 WeakPolarHBondContact O-CB 3.46Å; R274-L278 WeakPolarHBondContact O-CG 3.06Å; R274-L278 PolarHBondContact O-N 2.99Å
275	T	91.8	Very high	87.6	Confident	22 Å²	22	52.5 Å²	52.5	14%	0.135	28%	0.276	C	S	.	.	H	α-helix	trans	-63.5	-47.2	177.9	-59.2	0	0	0	0	110.8	N209 L213 H271 T272 H277 L278 V279	N209-T275 PolarHBondContact ND2-OG1 2.86Å; L213-T275 HydrophobicContact CD2-CG2 4.16Å; H271-T275 VanDerWaalsContact O-CB 3.31Å; H271-T275 WeakPolarHBondContact O-CB 3.25Å; H271-T275 PolarHBondContact O-N 3.24Å; H271-T275 VanDerWaalsContact O-N 3.1Å; H271-T275 PolarHBondContact O-OG1 3.25Å; T272-T275 PolarHBondContact O-N 3.12Å; T275-H277 VanDerWaalsContact C-N 3.29Å; T275-H277 PolarHBondContact O-N 2.93Å; T275-L278 PolarHBondContact O-N 3.23Å; T275-V279 HydrophobicContact CG2-CG2 4.26Å; T275-V279 WeakPolarHBondContact O-CB 3.36Å; T275-V279 VanDerWaalsContact O-CG2 3.3Å; T275-V279 WeakPolarHBondContact O-CG2 3.24Å; T275-V279 PolarHBondContact O-N 3.29Å
276	L	91.6	Very high	86.4	Confident	84 Å²	84	51.3 Å²	51.3	44%	0.44	27%	0.274	S	S	.	.	H	α-helix	trans	-60.1	-40.6	176.1	-177.9	63.4	0	0	0	112	T272 L273 T280 L290	T272-L276 WeakPolarHBondContact O-CB 3.48Å; T272-L276 PolarHBondContact O-N 2.98Å; L273-L276 PolarHBondContact O-N 3.38Å; L276-T280 HydrophobicContact CD1-CG2 3.74Å; L276-T280 HydrophobicContact CG-CG2 4.47Å; L276-T280 WeakPolarHBondContact O-CB 3.42Å; L276-T280 VanDerWaalsContact O-CG2 3.27Å; L276-T280 WeakPolarHBondContact O-CG2 3.41Å; L276-T280 PolarHBondContact O-N 2.74Å; L276-T280 PolarHBondContact O-OG1 2.91Å; L276-L290 HydrophobicContact CD2-CD1 3.91Å; L276-L290 HydrophobicContact CD2-CD2 4.45Å; L276-L290 HydrophobicContact CG-CD1 4.28Å; L276-L290 HydrophobicContact CG-CD2 4.15Å
277	H	88.1	Confident	85.5	Confident	28 Å²	28	55.4 Å²	55.4	13%	0.13	29%	0.291	C	S	.	.	H	α-helix	trans	-62.3	-50.3	176.4	-178.2	79.3	0	0	0	111.2	L273 R274 T275 T280 W281 L290 V294	L273-H277 WeakPolarHBondContact O-CB 3.31Å; L273-H277 PolarHBondContact O-N 3.47Å; R274-H277 PolarHBondContact O-N 3.13Å; T275-H277 VanDerWaalsContact C-N 3.29Å; T275-H277 PolarHBondContact O-N 2.93Å; H277-T280 PolarHBondContact O-N 2.84Å; H277-W281 VanDerWaalsContact O-CB 3.28Å; H277-W281 WeakPolarHBondContact O-CB 3.48Å; H277-W281 PolarHBondContact O-N 3.16Å; H277-L290 HydrophobicContact CB-CD2 4.27Å; H277-L290 HydrophobicContact CB-CG 4.33Å; H277-V294 HydrophobicContact CB-CG2 3.8Å
278	L	86.7	Confident	84.7	Confident	4 Å²	4	57.5 Å²	57.5	2%	0.021	30%	0.303	C	S	.	.	H	α-helix	trans	-66.8	-37.6	-179.1	-71	173.1	0	0	0	113.5	L197 Q206 N209 R274 T275	L197-L278 HydrophobicContact CD1-CD2 4.32Å; L197-L278 HydrophobicContact CD2-CD2 3.82Å; Q206-L278 HydrophobicContact CG-CB 4.24Å; Q206-L278 PolarHBondContact NE2-O 3.37Å; N209-L278 HydrophobicContact CB-CD1 3.47Å; N209-L278 VanDerWaalsContact CB-CD1 3.47Å; R274-L278 HydrophobicContact CG-CD1 4.07Å; R274-L278 WeakPolarHBondContact O-CB 3.46Å; R274-L278 WeakPolarHBondContact O-CG 3.06Å; R274-L278 PolarHBondContact O-N 2.99Å; T275-L278 PolarHBondContact O-N 3.23Å
279	V	86.6	Confident	84.4	Confident	77 Å²	77	66 Å²	66	47%	0.467	33%	0.331	S	S	.	.	H	α-helix	trans	-71.7	-37.2	179	169.7	0	0	0	0	111.4	T275	T275-V279 HydrophobicContact CG2-CG2 4.26Å; T275-V279 WeakPolarHBondContact O-CB 3.36Å; T275-V279 VanDerWaalsContact O-CG2 3.3Å; T275-V279 WeakPolarHBondContact O-CG2 3.24Å; T275-V279 PolarHBondContact O-N 3.29Å
280	T	85.9	Confident	84.1	Confident	37 Å²	37	65.6 Å²	65.6	23%	0.227	33%	0.327	C	S	.	.	S	Bend	trans	-97.8	8.5	-176.2	75	0	0	0	0	113.5	L276 H277 K287	L276-T280 HydrophobicContact CD1-CG2 3.74Å; L276-T280 HydrophobicContact CG-CG2 4.47Å; L276-T280 WeakPolarHBondContact O-CB 3.42Å; L276-T280 VanDerWaalsContact O-CG2 3.27Å; L276-T280 WeakPolarHBondContact O-CG2 3.41Å; L276-T280 PolarHBondContact O-N 2.74Å; L276-T280 PolarHBondContact O-OG1 2.91Å; H277-T280 PolarHBondContact O-N 2.84Å; T280-K287 PolarHBondContact O-NZ 3.4Å; T280-K287 PolarHBondContact OG1-NZ 3.34Å
281	W	80.6	Confident	83.8	Confident	74 Å²	74	67.7 Å²	67.7	28%	0.28	34%	0.336	S	S	.	.			trans	-67.3	132.9	178.3	-172.6	92.9	0	0	0	109.9	L199 I202 H277 V283	L199-W281 HydrophobicContact CD2-CH2 3.23Å; L199-W281 HydrophobicContact CD2-CZ2 3.24Å; I202-W281 HydrophobicContact CD1-CD2 3.35Å; I202-W281 HydrophobicContact CD1-CE3 3.26Å; I202-W281 HydrophobicContact CD1-CG 4.23Å; I202-W281 HydrophobicContact CD1-CH2 3.21Å; I202-W281 HydrophobicContact CD1-CZ2 3.34Å; I202-W281 HydrophobicContact CD1-CZ3 3.19Å; I202-W281 HydrophobicContact CG2-CE3 4.29Å; H277-W281 VanDerWaalsContact O-CB 3.28Å; H277-W281 WeakPolarHBondContact O-CB 3.48Å; H277-W281 PolarHBondContact O-N 3.16Å; W281-V283 HydrophobicContact CH2-CB 4.26Å; W281-V283 HydrophobicContact CH2-CG2 3.46Å; W281-V283 VanDerWaalsContact CH2-CG2 3.46Å; W281-V283 HydrophobicContact CZ3-CG2 3.67Å
282	K	75.4	Confident	83.6	Confident	138 Å²	138	72.1 Å²	72.1	60%	0.6	36%	0.356	S	S	*	.			trans	-139.6	139.7	175.2	-68.5	-173	175.6	-174.2	0	108.4	D284 I285	K282-D284 PolarHBondContact O-N 2.94Å; K282-I285 HydrophobicContact CB-CD1 4.15Å; K282-I285 HydrophobicContact CB-CG1 4.4Å; K282-I285 HydrophobicContact CD-CD1 3.98Å
283	V	67.4	Low	83.6	Confident	87 Å²	87	70 Å²	70	53%	0.527	35%	0.346	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.3	135.1	169.1	-168	0	0	0	0	107.4	W281 I285	W281-V283 HydrophobicContact CH2-CB 4.26Å; W281-V283 HydrophobicContact CH2-CG2 3.46Å; W281-V283 VanDerWaalsContact CH2-CG2 3.46Å; W281-V283 HydrophobicContact CZ3-CG2 3.67Å; V283-I285 PolarHBondContact O-N 3.06Å
284	D	63.7	Low	83.6	Confident	148 Å²	148	69 Å²	69	79%	0.791	34%	0.341	S	S	*	.	T	Hydrogen-bonded Turn	trans	72.3	11.1	174.9	-49.1	-39.5	0	0	0	119	K282	K282-D284 PolarHBondContact O-N 2.94Å
285	I	72	Confident	83.7	Confident	98 Å²	98	68.3 Å²	68.3	50%	0.503	34%	0.339	S	S	.	.			trans	-116.3	103.8	173	-55.6	-178.8	0	0	0	111.4	K282 V283 K287	K282-I285 HydrophobicContact CB-CD1 4.15Å; K282-I285 HydrophobicContact CB-CG1 4.4Å; K282-I285 HydrophobicContact CD-CD1 3.98Å; V283-I285 PolarHBondContact O-N 3.06Å; I285-K287 HydrophobicContact CG2-CG 4.14Å; I285-K287 PolarHBondContact O-N 3.41Å; I285-K287 VanDerWaalsContact O-N 3.09Å
286	C	69.4	Low	83.9	Confident	50 Å²	50	70.4 Å²	70.4	34%	0.338	35%	0.349	S	S	.	.			trans	-70.1	100.7	170.1	-54.9	0	0	0	0	110.2	C38 D288	C38-C286 HydrophobicContact CB-CB 3.88Å; C38-C286 WeakPolarHBondContact CB-SG 3.35Å; C38-C286 WeakPolarHBondContact SG-CB 3.3Å; C38-C286 CovalentContact SG-SG 2.04Å; C38-C286 PolarHBondContact SG-SG 2.9Å; C286-D288 VanDerWaalsContact C-N 3.29Å; C286-D288 WeakPolarHBondContact CB-OD1 3.27Å; C286-D288 PolarHBondContact O-N 2.81Å
287	K	77.4	Confident	84.2	Confident	85 Å²	85	67 Å²	67	37%	0.37	33%	0.332	S	S	.	.			trans	-88.4	66.4	168	-68.3	-172.4	-178.8	173.9	0	110.9	T280 I285 R289 L290 H291	T280-K287 PolarHBondContact O-NZ 3.4Å; T280-K287 PolarHBondContact OG1-NZ 3.34Å; I285-K287 HydrophobicContact CG2-CG 4.14Å; I285-K287 PolarHBondContact O-N 3.41Å; I285-K287 VanDerWaalsContact O-N 3.09Å; K287-R289 VanDerWaalsContact C-N 3.25Å; K287-R289 PolarHBondContact O-N 3.1Å; K287-R289 VanDerWaalsContact O-N 3.12Å; K287-L290 HydrophobicContact CB-CB 4.21Å; K287-L290 HydrophobicContact CD-CD2 4.31Å; K287-L290 PolarHBondContact O-N 3.08Å; K287-H291 PolarHBondContact O-N 3.01Å
288	D	79.3	Confident	84.5	Confident	44 Å²	44	67.1 Å²	67.1	24%	0.235	33%	0.333	C	S	.	.	H	α-helix	trans	-52.8	-40.1	-170.8	-77.9	-0.1	0	0	0	113	T39 C286 K292	T39-D288 PolarHBondContact N-OD2 3.13Å; T39-D288 PolarHBondContact OG1-OD2 2.75Å; C286-D288 VanDerWaalsContact C-N 3.29Å; C286-D288 WeakPolarHBondContact CB-OD1 3.27Å; C286-D288 PolarHBondContact O-N 2.81Å; D288-K292 WeakPolarHBondContact O-CB 3.38Å; D288-K292 PolarHBondContact O-N 3.32Å
289	R	88.3	Confident	85	Confident	232 Å²	232	67.1 Å²	67.1	88%	0.875	33%	0.334	S	S	*	.	H	α-helix	trans	-65.1	-46	178.3	-65.6	-175	-177.7	-176.4	0.7	113.3	K287 A293	K287-R289 VanDerWaalsContact C-N 3.25Å; K287-R289 PolarHBondContact O-N 3.1Å; K287-R289 VanDerWaalsContact O-N 3.12Å; R289-A293 WeakPolarHBondContact O-CB 3.42Å; R289-A293 PolarHBondContact O-N 3.44Å
290	L	90	Very high	85.5	Confident	28 Å²	28	66.1 Å²	66.1	15%	0.147	33%	0.325	C	S	.	.	H	α-helix	trans	-69.4	-42.6	-180	177.5	59.5	0	0	0	110.7	L273 L276 H277 K287 A293 V294	L273-L290 HydrophobicContact CD2-CD1 4.13Å; L276-L290 HydrophobicContact CD2-CD1 3.91Å; L276-L290 HydrophobicContact CD2-CD2 4.45Å; L276-L290 HydrophobicContact CG-CD1 4.28Å; L276-L290 HydrophobicContact CG-CD2 4.15Å; H277-L290 HydrophobicContact CB-CD2 4.27Å; H277-L290 HydrophobicContact CB-CG 4.33Å; K287-L290 HydrophobicContact CB-CB 4.21Å; K287-L290 HydrophobicContact CD-CD2 4.31Å; K287-L290 PolarHBondContact O-N 3.08Å; L290-A293 PolarHBondContact O-N 2.78Å; L290-V294 WeakPolarHBondContact O-CG2 3.39Å; L290-V294 PolarHBondContact O-N 3.45Å
291	H	88.7	Confident	86.1	Confident	49 Å²	49	64.5 Å²	64.5	23%	0.227	32%	0.316	C	S	.	.	H	α-helix	trans	-63.7	-43.6	177.4	-163.6	174.3	0	0	0	110.7	I40 K287 A293 V294 V295	I40-H291 HydrophobicContact CD1-CB 4.31Å; I40-H291 HydrophobicContact CG1-CB 4.08Å; K287-H291 PolarHBondContact O-N 3.01Å; H291-A293 VanDerWaalsContact C-N 3.31Å; H291-A293 PolarHBondContact O-N 2.95Å; H291-V294 PolarHBondContact O-N 3.42Å; H291-V294 VanDerWaalsContact O-N 3.16Å; H291-V295 WeakPolarHBondContact O-CG2 3.47Å; H291-V295 PolarHBondContact O-N 2.95Å
292	K	91.6	Very high	86.8	Confident	94 Å²	94	61.1 Å²	61.1	41%	0.409	30%	0.304	S	S	.	.	H	α-helix	trans	-57.5	-43.1	172.7	-173.2	171.4	-173.7	172.9	0	112.1	I40 F43 D288 V295 I296	I40-K292 HydrophobicContact CD1-CB 3.95Å; F43-K292 HydrophobicContact CD1-CD 4.34Å; F43-K292 HydrophobicContact CD1-CG 3.82Å; F43-K292 HydrophobicContact CE1-CD 4.3Å; F43-K292 HydrophobicContact CE1-CG 3.6Å; F43-K292 HydrophobicContact CG-CD 4.45Å; F43-K292 HydrophobicContact CG-CG 4.41Å; F43-K292 HydrophobicContact CZ-CD 4.39Å; F43-K292 VanDerWaalsContact CZ-CE 3.5Å; F43-K292 HydrophobicContact CZ-CG 4.05Å; D288-K292 WeakPolarHBondContact O-CB 3.38Å; D288-K292 PolarHBondContact O-N 3.32Å; K292-V295 WeakPolarHBondContact O-CB 3.1Å; K292-V295 PolarHBondContact O-N 2.63Å; K292-I296 HydrophobicContact CG-CD1 4.21Å; K292-I296 WeakPolarHBondContact O-CG1 3.43Å; K292-I296 PolarHBondContact O-N 2.89Å
293	A	94.7	Very high	87.9	Confident	33 Å²	33	55.2 Å²	55.2	27%	0.273	28%	0.28	S	S	.	.	H	α-helix	trans	-64.7	-39.8	177.1	0	0	0	0	0	112.2	L273 R289 L290 H291 I296 T297	L273-A293 HydrophobicContact CD1-CB 3.62Å; R289-A293 WeakPolarHBondContact O-CB 3.42Å; R289-A293 PolarHBondContact O-N 3.44Å; L290-A293 PolarHBondContact O-N 2.78Å; H291-A293 VanDerWaalsContact C-N 3.31Å; H291-A293 PolarHBondContact O-N 2.95Å; A293-I296 PolarHBondContact O-N 2.95Å; A293-T297 WeakPolarHBondContact O-CG2 3.41Å; A293-T297 PolarHBondContact O-N 3.4Å; A293-T297 PolarHBondContact O-OG1 3.3Å; A293-T297 VanDerWaalsContact O-OG1 3.13Å
294	V	93.4	Very high	89.2	Confident	17 Å²	17	51.1 Å²	51.1	10%	0.103	26%	0.256	C	S	.	.	H	α-helix	trans	-62.9	-40.9	172.9	172.6	0	0	0	0	111.9	L273 H277 L290 H291 I296 T297 L298	L273-V294 HydrophobicContact CB-CG2 3.8Å; L273-V294 WeakPolarHBondContact O-CG2 3.17Å; H277-V294 HydrophobicContact CB-CG2 3.8Å; L290-V294 WeakPolarHBondContact O-CG2 3.39Å; L290-V294 PolarHBondContact O-N 3.45Å; H291-V294 PolarHBondContact O-N 3.42Å; H291-V294 VanDerWaalsContact O-N 3.16Å; V294-I296 VanDerWaalsContact C-N 3.34Å; V294-I296 PolarHBondContact O-N 3.49Å; V294-T297 PolarHBondContact O-N 2.65Å; V294-T297 PolarHBondContact O-OG1 3.41Å; V294-L298 WeakPolarHBondContact O-CB 3.46Å; V294-L298 PolarHBondContact O-N 3.11Å
295	V	94.1	Very high	90.8	Very high	5 Å²	5	44 Å²	44	3%	0.03	22%	0.218	C	C	.	.	H	α-helix	trans	-59.6	-46.1	175.9	163	0	0	0	0	110.8	I40 F43 K44 F47 F48 H291 K292 A299	I40-V295 HydrophobicContact CD1-CG2 4.16Å; F43-V295 HydrophobicContact CD1-CG1 4.06Å; F43-V295 HydrophobicContact CE1-CB 4.32Å; F43-V295 HydrophobicContact CE1-CG1 3.66Å; K44-V295 HydrophobicContact CD-CG2 4.25Å; K44-V295 HydrophobicContact CG-CG1 4.42Å; K44-V295 HydrophobicContact CG-CG2 3.8Å; F47-V295 HydrophobicContact CD1-CG1 3.69Å; F47-V295 HydrophobicContact CE1-CG1 4.03Å; F48-V295 HydrophobicContact CE1-CG1 3.83Å; F48-V295 HydrophobicContact CE2-CG1 3.94Å; F48-V295 HydrophobicContact CE2-CG2 4.26Å; F48-V295 HydrophobicContact CZ-CB 4.12Å; F48-V295 HydrophobicContact CZ-CG1 3.53Å; F48-V295 HydrophobicContact CZ-CG2 4.01Å; H291-V295 WeakPolarHBondContact O-CG2 3.47Å; H291-V295 PolarHBondContact O-N 2.95Å; K292-V295 WeakPolarHBondContact O-CB 3.1Å; K292-V295 PolarHBondContact O-N 2.63Å; V295-A299 PolarHBondContact O-N 2.88Å; V295-A299 VanDerWaalsContact O-N 3.1Å
296	I	96.8	Very high	91.9	Very high	67 Å²	67	40.9 Å²	40.9	34%	0.344	20%	0.204	S	C	.	.	H	α-helix	trans	-64.1	-47.5	178	-66.9	165.4	0	0	0	110.7	F43 F47 K292 A293 V294 L298 A299 L300	F43-I296 HydrophobicContact CE1-CG1 4.3Å; F43-I296 HydrophobicContact CZ-CD1 4.4Å; F43-I296 HydrophobicContact CZ-CG1 4.2Å; F47-I296 HydrophobicContact CE1-CG1 4.33Å; F47-I296 HydrophobicContact CZ-CG1 4.09Å; K292-I296 HydrophobicContact CG-CD1 4.21Å; K292-I296 WeakPolarHBondContact O-CG1 3.43Å; K292-I296 PolarHBondContact O-N 2.89Å; A293-I296 PolarHBondContact O-N 2.95Å; V294-I296 VanDerWaalsContact C-N 3.34Å; V294-I296 PolarHBondContact O-N 3.49Å; I296-L298 VanDerWaalsContact C-N 3.34Å; I296-L298 PolarHBondContact O-N 2.83Å; I296-A299 WeakPolarHBondContact O-CB 3.11Å; I296-A299 PolarHBondContact O-N 3.42Å; I296-L300 HydrophobicContact CG2-CD1 4.45Å; I296-L300 PolarHBondContact O-N 3.02Å
297	T	97.4	Very high	93	Very high	11 Å²	11	41.7 Å²	41.7	7%	0.067	20%	0.202	C	C	.	.	H	α-helix	trans	-71.5	-28.8	-178.4	57.6	0	0	0	0	113.1	P269 L273 A293 V294 A299 L300 A301	P269-T297 HydrophobicContact CB-CG2 3.49Å; P269-T297 VanDerWaalsContact CB-CG2 3.49Å; L273-T297 HydrophobicContact CD1-CG2 3.62Å; A293-T297 WeakPolarHBondContact O-CG2 3.41Å; A293-T297 PolarHBondContact O-N 3.4Å; A293-T297 PolarHBondContact O-OG1 3.3Å; A293-T297 VanDerWaalsContact O-OG1 3.13Å; V294-T297 PolarHBondContact O-N 2.65Å; V294-T297 PolarHBondContact O-OG1 3.41Å; T297-A299 VanDerWaalsContact C-N 3.33Å; T297-L300 PolarHBondContact O-N 3.45Å; T297-A301 WeakPolarHBondContact O-CB 3.43Å; T297-A301 PolarHBondContact O-N 3.49Å
298	L	95.9	Very high	93.8	Very high	32 Å²	32	37.6 Å²	37.6	17%	0.168	18%	0.184	C	C	.	.	H	α-helix	trans	-63.6	-40.6	169.2	175.1	60.7	0	0	0	111.4	F48 L125 Y270 V294 I296 A301 A302	F48-L298 HydrophobicContact CE1-CD2 4.45Å; F48-L298 HydrophobicContact CZ-CD2 4.24Å; L125-L298 HydrophobicContact CD2-CD1 3.92Å; Y270-L298 HydrophobicContact CD2-CB 3.97Å; Y270-L298 HydrophobicContact CD2-CD1 4.26Å; Y270-L298 HydrophobicContact CE2-CB 3.87Å; Y270-L298 HydrophobicContact CE2-CD1 3.61Å; Y270-L298 HydrophobicContact CE2-CG 4.28Å; V294-L298 WeakPolarHBondContact O-CB 3.46Å; V294-L298 PolarHBondContact O-N 3.11Å; I296-L298 VanDerWaalsContact C-N 3.34Å; I296-L298 PolarHBondContact O-N 2.83Å; L298-A301 WeakPolarHBondContact O-CB 3.28Å; L298-A301 PolarHBondContact O-N 2.81Å; L298-A302 PolarHBondContact O-N 2.84Å
299	A	96.9	Very high	94.5	Very high	3 Å²	3	36.6 Å²	36.6	3%	0.025	18%	0.18	C	C	.	.	H	α-helix	trans	-66.7	-39	175.5	0	0	0	0	0	111.9	F47 V51 V295 I296 T297 A302 A303	F47-A299 HydrophobicContact CE1-CB 3.69Å; F47-A299 HydrophobicContact CZ-CB 4.13Å; V51-A299 HydrophobicContact CG1-CB 3.89Å; V295-A299 PolarHBondContact O-N 2.88Å; V295-A299 VanDerWaalsContact O-N 3.1Å; I296-A299 WeakPolarHBondContact O-CB 3.11Å; I296-A299 PolarHBondContact O-N 3.42Å; T297-A299 VanDerWaalsContact C-N 3.33Å; A299-A302 PolarHBondContact O-N 3.1Å; A299-A303 WeakPolarHBondContact O-CB 3.08Å; A299-A303 PolarHBondContact O-N 3.12Å
300	L	97.3	Very high	94.7	Very high	56 Å²	56	29.6 Å²	29.6	29%	0.293	16%	0.159	S	C	.	.	H	α-helix	trans	-62.5	-40.9	171	-69.4	173.2	0	0	0	112	C266 I296 T297 A302 A303 N304	C266-L300 WeakPolarHBondContact CB-O 3.32Å; I296-L300 HydrophobicContact CG2-CD1 4.45Å; I296-L300 PolarHBondContact O-N 3.02Å; T297-L300 PolarHBondContact O-N 3.45Å; L300-A302 VanDerWaalsContact C-N 3.33Å; L300-A302 PolarHBondContact O-N 3.18Å; L300-A303 WeakPolarHBondContact O-CB 3.31Å; L300-A303 PolarHBondContact O-N 3.23Å; L300-A303 VanDerWaalsContact O-N 3.16Å; L300-N304 PolarHBondContact O-N 2.91Å
301	A	96.9	Very high	94.9	Very high	4 Å²	4	28.2 Å²	28.2	3%	0.033	15%	0.152	C	C	.	.	H	α-helix	trans	-60.2	-43.3	174	0	0	0	0	0	111.1	C266 Y270 T297 L298 A303 N304	C266-A301 WeakPolarHBondContact O-CA 3.46Å; C266-A301 WeakPolarHBondContact O-CB 3.4Å; Y270-A301 HydrophobicContact CD1-CB 4.23Å; Y270-A301 HydrophobicContact CG-CB 4.04Å; T297-A301 WeakPolarHBondContact O-CB 3.43Å; T297-A301 PolarHBondContact O-N 3.49Å; L298-A301 WeakPolarHBondContact O-CB 3.28Å; L298-A301 PolarHBondContact O-N 2.81Å; A301-A303 VanDerWaalsContact C-N 3.33Å; A301-A303 PolarHBondContact O-N 2.95Å; A301-N304 VanDerWaalsContact O-CB 3.29Å; A301-N304 WeakPolarHBondContact O-CB 3.38Å; A301-N304 PolarHBondContact O-N 2.04Å; A301-N304 PolarHBondContact O-ND2 2.8Å
302	A	96.9	Very high	95.1	Very high	2 Å²	2	25.9 Å²	25.9	2%	0.017	14%	0.142	C	C	.	.	H	α-helix	trans	-64.8	-35.6	174.3	0	0	0	0	0	112.8	Y52 I55 F94 L298 A299 L300 N304 T305	Y52-A302 HydrophobicContact CE1-CB 4.49Å; I55-A302 HydrophobicContact CD1-CB 4.02Å; F94-A302 HydrophobicContact CE1-CB 3.93Å; F94-A302 HydrophobicContact CZ-CB 3.82Å; L298-A302 PolarHBondContact O-N 2.84Å; A299-A302 PolarHBondContact O-N 3.1Å; L300-A302 VanDerWaalsContact C-N 3.33Å; L300-A302 PolarHBondContact O-N 3.18Å; A302-N304 PolarHBondContact O-N 3.42Å; A302-T305 PolarHBondContact O-N 3.23Å; A302-T305 PolarHBondContact O-OG1 2.76Å
303	A	96.7	Very high	95.1	Very high	14 Å²	14	26.2 Å²	26.2	12%	0.116	14%	0.141	C	C	.	.	H	α-helix	trans	-67.5	-11.3	179.1	0	0	0	0	0	113.9	I55 A299 L300 A301 T305 C306 F307	I55-A303 HydrophobicContact CD1-CB 3.87Å; I55-A303 HydrophobicContact CG1-CB 4.05Å; A299-A303 WeakPolarHBondContact O-CB 3.08Å; A299-A303 PolarHBondContact O-N 3.12Å; L300-A303 WeakPolarHBondContact O-CB 3.31Å; L300-A303 PolarHBondContact O-N 3.23Å; L300-A303 VanDerWaalsContact O-N 3.16Å; A301-A303 VanDerWaalsContact C-N 3.33Å; A301-A303 PolarHBondContact O-N 2.95Å; A303-T305 PolarHBondContact O-N 3.06Å; A303-T305 VanDerWaalsContact O-N 3.09Å; A303-C306 WeakPolarHBondContact O-CB 3.32Å; A303-C306 PolarHBondContact O-N 3.36Å; A303-F307 HydrophobicContact CB-CE2 4.15Å; A303-F307 VanDerWaalsContact O-CD2 3.32Å; A303-F307 WeakPolarHBondContact O-CD2 3.14Å
304	N	95.8	Very high	94.9	Very high	1 Å²	1	28.8 Å²	28.8	1%	0.005	15%	0.146	C	C	.	.	H	α-helix	trans	-48.3	-38.8	173.4	90.9	94	0	0	0	112.4	I262 C266 F267 L300 A301 A302 C306 F307 N308	I262-N304 HydrophobicContact CG2-CB 4.24Å; C266-N304 HydrophobicContact CB-CB 3.93Å; F267-N304 HydrophobicContact CE1-CB 3.97Å; F267-N304 HydrophobicContact CZ-CB 3.86Å; L300-N304 PolarHBondContact O-N 2.91Å; A301-N304 VanDerWaalsContact O-CB 3.29Å; A301-N304 WeakPolarHBondContact O-CB 3.38Å; A301-N304 PolarHBondContact O-N 2.04Å; A301-N304 PolarHBondContact O-ND2 2.8Å; A302-N304 PolarHBondContact O-N 3.42Å; N304-C306 PolarHBondContact O-N 2.91Å; N304-C306 VanDerWaalsContact O-N 3.17Å; N304-F307 PolarHBondContact O-N 3.28Å; N304-N308 PolarHBondContact O-N 3.32Å
305	T	96.3	Very high	94.5	Very high	0 Å²	0	28 Å²	28	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-60.2	-24.8	179.3	60.8	0	0	0	0	114	N63 D91 F94 I95 A302 A303 P309	N63-T305 PolarHBondContact ND2-O 2.98Å; D91-T305 HydrophobicContact CB-CG2 3.96Å; D91-T305 VanDerWaalsContact OD1-CG2 3.3Å; D91-T305 WeakPolarHBondContact OD1-CG2 3.29Å; F94-T305 HydrophobicContact CD1-CG2 3.78Å; F94-T305 HydrophobicContact CE1-CG2 4.25Å; I95-T305 HydrophobicContact CD1-CG2 4.27Å; I95-T305 HydrophobicContact CG1-CG2 4.28Å; A302-T305 PolarHBondContact O-N 3.23Å; A302-T305 PolarHBondContact O-OG1 2.76Å; A303-T305 PolarHBondContact O-N 3.06Å; A303-T305 VanDerWaalsContact O-N 3.09Å; T305-P309 WeakPolarHBondContact O-CD 3.03Å
306	C	95.3	Very high	94	Very high	32 Å²	32	28.1 Å²	28.1	22%	0.216	14%	0.144	C	C	.	.	H	α-helix	trans	-83.4	-21.8	176.3	-65.4	0	0	0	0	112.8	A303 N304	A303-C306 WeakPolarHBondContact O-CB 3.32Å; A303-C306 PolarHBondContact O-N 3.36Å; N304-C306 PolarHBondContact O-N 2.91Å; N304-C306 VanDerWaalsContact O-N 3.17Å
307	F	93.1	Very high	93.4	Very high	66 Å²	66	26.6 Å²	26.6	29%	0.289	14%	0.135	S	C	.	.	H	α-helix	trans	-88	-25.7	-179.5	-57.4	-56.7	0	0	0	112.3	I262 L265 A303 N304 L310	I262-F307 HydrophobicContact CD1-CB 4.18Å; I262-F307 HydrophobicContact CG1-CB 3.98Å; L265-F307 HydrophobicContact CD2-CE2 4.32Å; L265-F307 HydrophobicContact CD2-CZ 4.29Å; A303-F307 HydrophobicContact CB-CE2 4.15Å; A303-F307 VanDerWaalsContact O-CD2 3.32Å; A303-F307 WeakPolarHBondContact O-CD2 3.14Å; N304-F307 PolarHBondContact O-N 3.28Å; F307-L310 HydrophobicContact CD1-CD1 4.48Å; F307-L310 VanDerWaalsContact O-CB 3.26Å; F307-L310 WeakPolarHBondContact O-CB 3.48Å; F307-L310 PolarHBondContact O-N 2.93Å
308	N	94.1	Very high	92.8	Very high	0 Å²	0	27.9 Å²	27.9	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-57.6	-38	179.5	-68.1	-25.5	0	0	0	114.1	L87 D91 I262 N304 L310 L311 Y312	L87-N308 HydrophobicContact CD2-CB 4.31Å; D91-N308 PolarHBondContact OD2-ND2 3.12Å; I262-N308 WeakPolarHBondContact CD1-OD1 3.41Å; N304-N308 PolarHBondContact O-N 3.32Å; N308-L310 PolarHBondContact O-N 2.96Å; N308-L310 VanDerWaalsContact O-N 3.17Å; N308-L311 WeakPolarHBondContact O-CA 3.16Å; N308-L311 WeakPolarHBondContact O-CB 3.32Å; N308-L311 PolarHBondContact O-N 3.38Å; N308-Y312 HydrophobicContact CB-CE1 4.42Å; N308-Y312 HydrophobicContact CB-CE2 4.32Å; N308-Y312 WeakPolarHBondContact CB-OH 3.21Å; N308-Y312 WeakPolarHBondContact O-CD1 3.43Å; N308-Y312 PolarHBondContact O-N 2.84Å
309	P	94.3	Very high	92.4	Very high	22 Å²	22	26.8 Å²	26.8	14%	0.143	14%	0.136	C	C	.	.	H	α-helix	trans	-54.7	-31	171.4	-30.6	37.2	0	0	0	115.6	T305 L311 Y312 Y313	T305-P309 WeakPolarHBondContact O-CD 3.03Å; P309-L311 VanDerWaalsContact C-N 3.31Å; P309-L311 PolarHBondContact O-N 2.99Å; P309-Y312 VanDerWaalsContact CA-CD2 3.49Å; P309-Y312 HydrophobicContact CB-CD2 4.42Å; P309-Y312 HydrophobicContact CG-CE2 4.46Å; P309-Y312 PolarHBondContact O-N 2.91Å; P309-Y313 PolarHBondContact O-N 3.2Å
310	L	93.3	Very high	92.1	Very high	85 Å²	85	30.1 Å²	30.1	45%	0.445	15%	0.15	S	C	.	.	H	α-helix	trans	-64.2	-40.6	174.3	-58.2	173.8	0	0	0	110.6	F307 N308 Y312 Y313 F314	F307-L310 HydrophobicContact CD1-CD1 4.48Å; F307-L310 VanDerWaalsContact O-CB 3.26Å; F307-L310 WeakPolarHBondContact O-CB 3.48Å; F307-L310 PolarHBondContact O-N 2.93Å; N308-L310 PolarHBondContact O-N 2.96Å; N308-L310 VanDerWaalsContact O-N 3.17Å; L310-Y312 VanDerWaalsContact C-N 3.32Å; L310-Y312 PolarHBondContact O-N 3.14Å; L310-Y313 PolarHBondContact O-N 3.43Å; L310-F314 HydrophobicContact CB-CD2 4.31Å; L310-F314 HydrophobicContact CD2-CE2 4.24Å; L310-F314 WeakPolarHBondContact O-CB 3.37Å; L310-F314 WeakPolarHBondContact O-CD2 3.5Å; L310-F314 PolarHBondContact O-N 2.81Å
311	L	92.7	Very high	91.7	Very high	0 Å²	0	30.5 Å²	30.5	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-60.9	-42.6	176.1	-174.8	63.8	0	0	0	111.2	M84 L136 L139 T255 I258 N308 P309 A315 G316	M84-L311 HydrophobicContact CE-CG 4.35Å; L136-L311 HydrophobicContact CD2-CD2 3.45Å; L136-L311 VanDerWaalsContact CD2-CD2 3.45Å; L139-L311 HydrophobicContact CD2-CD2 3.55Å; L139-L311 HydrophobicContact CD2-CG 4.16Å; T255-L311 HydrophobicContact CG2-CD1 4.06Å; I258-L311 HydrophobicContact CB-CD1 4.19Å; I258-L311 HydrophobicContact CD1-CD1 4.44Å; I258-L311 HydrophobicContact CG2-CB 4.01Å; I258-L311 HydrophobicContact CG2-CD1 4.16Å; N308-L311 WeakPolarHBondContact O-CA 3.16Å; N308-L311 WeakPolarHBondContact O-CB 3.32Å; N308-L311 PolarHBondContact O-N 3.38Å; P309-L311 VanDerWaalsContact C-N 3.31Å; P309-L311 PolarHBondContact O-N 2.99Å; L311-A315 HydrophobicContact CD1-CB 3.88Å; L311-A315 CarbonylContact O-C 3.53Å; L311-A315 VanDerWaalsContact O-CA 3.32Å; L311-A315 WeakPolarHBondContact O-CA 3.34Å; L311-A315 VanDerWaalsContact O-CB 3.28Å; L311-A315 WeakPolarHBondContact O-CB 3.46Å; L311-A315 PolarHBondContact O-N 3.3Å; L311-G316 PolarHBondContact O-N 3.38Å
312	Y	93	Very high	91.4	Very high	0 Å²	0	30.6 Å²	30.6	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-65.7	-43.5	179.3	-48.3	-29	0	0	0	111.6	S66 F70 M84 L87 A88 N308 P309 L310 G316 F319	S66-Y312 VanDerWaalsContact CB-CD2 3.48Å; S66-Y312 VanDerWaalsContact OG-CD2 3.32Å; S66-Y312 WeakPolarHBondContact OG-CD2 3.19Å; F70-Y312 HydrophobicContact CE2-CD1 4.26Å; F70-Y312 HydrophobicContact CE2-CD2 4.1Å; F70-Y312 AromaticContact CE2-CG 3.94Å; F70-Y312 HydrophobicContact CE2-CG 3.94Å; F70-Y312 HydrophobicContact CZ-CD1 4.19Å; F70-Y312 AromaticContact CZ-CG 3.97Å; F70-Y312 HydrophobicContact CZ-CG 3.97Å; M84-Y312 HydrophobicContact CB-CD1 3.83Å; M84-Y312 HydrophobicContact CB-CE1 3.9Å; M84-Y312 HydrophobicContact CG-CD1 3.77Å; M84-Y312 HydrophobicContact CG-CE1 4.03Å; M84-Y312 HydrophobicContact SD-CD1 3.95Å; L87-Y312 HydrophobicContact CD2-CE1 4.08Å; L87-Y312 VanDerWaalsContact CG-OH 3.28Å; L87-Y312 WeakPolarHBondContact CG-OH 3.49Å; A88-Y312 HydrophobicContact CB-CE2 3.91Å; A88-Y312 PolarHBondContact N-OH 3.14Å; N308-Y312 HydrophobicContact CB-CE1 4.42Å; N308-Y312 HydrophobicContact CB-CE2 4.32Å; N308-Y312 WeakPolarHBondContact CB-OH 3.21Å; N308-Y312 WeakPolarHBondContact O-CD1 3.43Å; N308-Y312 PolarHBondContact O-N 2.84Å; P309-Y312 VanDerWaalsContact CA-CD2 3.49Å; P309-Y312 HydrophobicContact CB-CD2 4.42Å; P309-Y312 HydrophobicContact CG-CE2 4.46Å; P309-Y312 PolarHBondContact O-N 2.91Å; L310-Y312 VanDerWaalsContact C-N 3.32Å; L310-Y312 PolarHBondContact O-N 3.14Å; Y312-G316 WeakPolarHBondContact O-CA 3.15Å; Y312-G316 PolarHBondContact O-N 3.16Å; Y312-F319 WeakPolarHBondContact O-CG 3.21Å
313	Y	92.8	Very high	91.1	Very high	101 Å²	101	32.2 Å²	32.2	40%	0.396	16%	0.16	S	C	.	.	H	α-helix	trans	-69.2	-43.3	-178.6	-178.2	-104.6	0	0	0	113.2	P309 L310 F319 K320	P309-Y313 PolarHBondContact O-N 3.2Å; L310-Y313 PolarHBondContact O-N 3.43Å; Y313-F319 HydrophobicContact CD2-CD1 4.27Å; Y313-F319 HydrophobicContact CD2-CE1 4.19Å; Y313-K320 HydrophobicContact CD2-CG 4.4Å; Y313-K320 HydrophobicContact CE2-CD 4.21Å; Y313-K320 HydrophobicContact CE2-CG 4.12Å; Y313-K320 WeakPolarHBondContact O-CE 3.39Å
314	F	89.6	Confident	90.8	Very high	86 Å²	86	39 Å²	39	38%	0.377	18%	0.183	S	C	.	.	H	α-helix	trans	-90.3	-31.9	-174.6	-68.8	-67.9	0	0	0	113.9	T254 I258 L310	T254-F314 HydrophobicContact CG2-CB 3.66Å; I258-F314 HydrophobicContact CD1-CB 4.16Å; I258-F314 HydrophobicContact CD1-CD2 4.33Å; L310-F314 HydrophobicContact CB-CD2 4.31Å; L310-F314 HydrophobicContact CD2-CE2 4.24Å; L310-F314 WeakPolarHBondContact O-CB 3.37Å; L310-F314 WeakPolarHBondContact O-CD2 3.5Å; L310-F314 PolarHBondContact O-N 2.81Å
315	A	84.8	Confident	90.4	Very high	0 Å²	0	41 Å²	41	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-117.5	1.3	-175.6	0	0	0	0	0	114.1	R143 T255 L311	R143-A315 PolarHBondContact NH2-O 3.18Å; T255-A315 VanDerWaalsContact OG1-CB 3.29Å; T255-A315 WeakPolarHBondContact OG1-CB 3.3Å; L311-A315 HydrophobicContact CD1-CB 3.88Å; L311-A315 CarbonylContact O-C 3.53Å; L311-A315 VanDerWaalsContact O-CA 3.32Å; L311-A315 WeakPolarHBondContact O-CA 3.34Å; L311-A315 VanDerWaalsContact O-CB 3.28Å; L311-A315 WeakPolarHBondContact O-CB 3.46Å; L311-A315 PolarHBondContact O-N 3.3Å
316	G	84.6	Confident	90	Very high	9 Å²	9	41.4 Å²	41.4	9%	0.093	20%	0.199	C	C	.	.			trans	-65.6	150.9	177.1	0	0	0	0	0	114.5	K251 L311 Y312	K251-G316 PolarHBondContact NZ-O 2.88Å; L311-G316 PolarHBondContact O-N 3.38Å; Y312-G316 WeakPolarHBondContact O-CA 3.15Å; Y312-G316 PolarHBondContact O-N 3.16Å
317	E	84.1	Confident	89.7	Confident	34 Å²	34	45 Å²	45	16%	0.159	22%	0.216	C	C	.	.	S	Bend	trans	-85.2	117.4	168.9	-72.2	-49.2	134.9	0	0	110.8	T78 V80 N81 R143 K251 F319	T78-E317 HydrophobicContact CG2-CB 4.08Å; T78-E317 HydrophobicContact CG2-CG 4.13Å; T78-E317 WeakPolarHBondContact OG1-CB 3.43Å; V80-E317 HydrophobicContact CB-CG 4.32Å; V80-E317 HydrophobicContact CG1-CG 4.44Å; N81-E317 PolarHBondContact ND2-O 3.37Å; N81-E317 PolarHBondContact OD1-O 3.36Å; R143-E317 IonicContact CZ-OE1 2.75Å; R143-E317 IonicContact NH1-OE1 3.12Å; R143-E317 PolarHBondContact NH1-OE1 3.11Å; R143-E317 IonicContact NH2-OE1 2.79Å; R143-E317 PolarHBondContact NH2-OE1 2.96Å; K251-E317 VanDerWaalsContact CD-OE1 3.27Å; K251-E317 WeakPolarHBondContact CD-OE1 3.46Å; K251-E317 IonicContact NZ-OE1 3.06Å; K251-E317 PolarHBondContact NZ-OE1 3.29Å; K251-E317 IonicContact NZ-OE2 2.73Å; K251-E317 PolarHBondContact NZ-OE2 3.29Å; E317-F319 PolarHBondContact O-N 3.03Å
318	N	85.1	Confident	89.4	Confident	39 Å²	39	51.4 Å²	51.4	21%	0.209	24%	0.238	C	C	.	.	S	Bend	trans	57.9	14.2	179.8	-49.8	106.8	0	0	0	114.9	Y74 K320 D321 R322	Y74-N318 HydrophobicContact CD1-CB 3.92Å; Y74-N318 HydrophobicContact CE1-CB 3.44Å; Y74-N318 VanDerWaalsContact CE1-CB 3.44Å; N318-K320 PolarHBondContact O-N 2.74Å; N318-D321 HydrophobicContact CB-CB 4.43Å; N318-D321 PolarHBondContact ND2-OD2 3.06Å; N318-D321 PolarHBondContact O-N 2.78Å; N318-D321 VanDerWaalsContact O-N 3.13Å; N318-R322 WeakPolarHBondContact O-CG 3.38Å; N318-R322 PolarHBondContact O-N 3.03Å
319	F	87.5	Confident	88.3	Confident	8 Å²	8	58.1 Å²	58.1	4%	0.035	27%	0.267	C	S	.	.	H	α-helix	trans	-56.7	-48.7	-178.9	-174.7	-90.4	0	0	0	111.7	V69 F70 Y312 Y313 E317 D321 R322 L323	V69-F319 HydrophobicContact CB-CD2 4.37Å; V69-F319 HydrophobicContact CB-CE2 3.79Å; V69-F319 HydrophobicContact CB-CZ 4.05Å; V69-F319 HydrophobicContact CG1-CD1 4.47Å; V69-F319 HydrophobicContact CG1-CD2 3.67Å; V69-F319 HydrophobicContact CG1-CE1 4.38Å; V69-F319 HydrophobicContact CG1-CE2 3.58Å; V69-F319 HydrophobicContact CG1-CG 4.15Å; V69-F319 HydrophobicContact CG1-CZ 3.96Å; V69-F319 HydrophobicContact CG2-CE2 4.45Å; V69-F319 HydrophobicContact CG2-CZ 4.21Å; F70-F319 HydrophobicContact CD1-CD2 4.22Å; F70-F319 AromaticContact CE1-CD2 3.63Å; F70-F319 HydrophobicContact CE1-CD2 3.63Å; F70-F319 HydrophobicContact CE1-CE2 4.24Å; F70-F319 HydrophobicContact CE2-CD2 4.36Å; F70-F319 HydrophobicContact CE2-CE2 4.19Å; F70-F319 AromaticContact CZ-CD2 3.69Å; F70-F319 HydrophobicContact CZ-CD2 3.69Å; F70-F319 AromaticContact CZ-CE2 3.97Å; F70-F319 HydrophobicContact CZ-CE2 3.97Å; Y312-F319 WeakPolarHBondContact O-CG 3.21Å; Y313-F319 HydrophobicContact CD2-CD1 4.27Å; Y313-F319 HydrophobicContact CD2-CE1 4.19Å; E317-F319 PolarHBondContact O-N 3.03Å; F319-D321 VanDerWaalsContact C-N 3.31Å; F319-D321 PolarHBondContact O-N 2.82Å; F319-R322 PolarHBondContact O-N 3.44Å; F319-L323 WeakPolarHBondContact O-CB 3.48Å; F319-L323 PolarHBondContact O-N 3.04Å
320	K	89.6	Confident	86.7	Confident	74 Å²	74	59.7 Å²	59.7	32%	0.322	29%	0.288	S	S	.	.	H	α-helix	trans	-64.2	-35.6	178.1	-60.5	-170	-177.4	-163.1	0	112.6	Y313 N318 R324	Y313-K320 HydrophobicContact CD2-CG 4.4Å; Y313-K320 HydrophobicContact CE2-CD 4.21Å; Y313-K320 HydrophobicContact CE2-CG 4.12Å; Y313-K320 WeakPolarHBondContact O-CE 3.39Å; N318-K320 PolarHBondContact O-N 2.74Å; K320-R324 WeakPolarHBondContact O-CB 3.44Å; K320-R324 VanDerWaalsContact O-CG 3.3Å; K320-R324 WeakPolarHBondContact O-CG 3.33Å; K320-R324 PolarHBondContact O-N 2.78Å
321	D	88.9	Confident	84.5	Confident	64 Å²	64	63.1 Å²	63.1	34%	0.342	30%	0.301	S	S	.	.	H	α-helix	trans	-69.5	-43.2	178.5	-54.6	-36.5	0	0	0	110.9	Y74 N318 F319 R324 S325	Y74-D321 HydrophobicContact CE2-CB 3.79Å; Y74-D321 WeakPolarHBondContact OH-CB 3.23Å; Y74-D321 PolarHBondContact OH-OD2 3.09Å; N318-D321 HydrophobicContact CB-CB 4.43Å; N318-D321 PolarHBondContact ND2-OD2 3.06Å; N318-D321 PolarHBondContact O-N 2.78Å; N318-D321 VanDerWaalsContact O-N 3.13Å; F319-D321 VanDerWaalsContact C-N 3.31Å; F319-D321 PolarHBondContact O-N 2.82Å; D321-R324 PolarHBondContact O-N 3.4Å; D321-S325 WeakPolarHBondContact O-CB 3.37Å; D321-S325 PolarHBondContact O-N 2.76Å
322	R	90.1	Very high	82.3	Confident	6 Å²	6	72.6 Å²	72.6	2%	0.023	36%	0.363	C	S	.	.	H	α-helix	trans	-61.9	-44.8	173.9	-71.2	-178.5	-170	-151.9	-1.7	111.5	V69 F70 Y74 K76 S77 N81 N318 F319 S325 A326	V69-R322 HydrophobicContact CG1-CB 3.75Å; F70-R322 PolarHBondContact O-NH1 2.77Å; Y74-R322 VanDerWaalsContact CB-NE 3.35Å; Y74-R322 HydrophobicContact CD1-CG 4.43Å; Y74-R322 HydrophobicContact CD2-CG 3.56Å; Y74-R322 HydrophobicContact CE2-CG 4.24Å; Y74-R322 HydrophobicContact CG-CG 3.68Å; K76-R322 PolarHBondContact O-NH2 3.43Å; S77-R322 PolarHBondContact OG-NH2 3Å; N81-R322 PolarHBondContact ND2-NH2 3.45Å; N318-R322 WeakPolarHBondContact O-CG 3.38Å; N318-R322 PolarHBondContact O-N 3.03Å; F319-R322 PolarHBondContact O-N 3.44Å; R322-S325 WeakPolarHBondContact O-CB 3.27Å; R322-S325 PolarHBondContact O-N 2.77Å; R322-A326 WeakPolarHBondContact O-CB 3.28Å; R322-A326 PolarHBondContact O-N 2.72Å
323	L	91.2	Very high	81.8	Confident	36 Å²	36	76.3 Å²	76.3	19%	0.188	38%	0.381	C	S	.	.	H	α-helix	trans	-60.4	-47.5	176.5	178.8	60.8	0	0	0	111.5	L65 V69 F319 S325 A326 L327	L65-L323 HydrophobicContact CD1-CD1 4.4Å; V69-L323 HydrophobicContact CG1-CB 4.32Å; V69-L323 HydrophobicContact CG2-CB 4.23Å; V69-L323 HydrophobicContact CG2-CD1 3.79Å; F319-L323 WeakPolarHBondContact O-CB 3.48Å; F319-L323 PolarHBondContact O-N 3.04Å; L323-S325 VanDerWaalsContact C-N 3.31Å; L323-S325 PolarHBondContact O-N 2.86Å; L323-A326 PolarHBondContact O-N 2.73Å; L323-L327 HydrophobicContact CD1-CD1 4.33Å; L323-L327 HydrophobicContact CD1-CG 4.35Å; L323-L327 HydrophobicContact CG-CD1 4.24Å; L323-L327 WeakPolarHBondContact O-CG 3.35Å; L323-L327 PolarHBondContact O-N 2.87Å
324	R	90.2	Very high	81.2	Confident	157 Å²	157	74.9 Å²	74.9	59%	0.592	38%	0.381	S	S	*	.	H	α-helix	trans	-60.5	-40.6	175.5	-74.4	172.7	-177.8	172.9	-2.3	112.3	K320 D321 R328	K320-R324 WeakPolarHBondContact O-CB 3.44Å; K320-R324 VanDerWaalsContact O-CG 3.3Å; K320-R324 WeakPolarHBondContact O-CG 3.33Å; K320-R324 PolarHBondContact O-N 2.78Å; D321-R324 PolarHBondContact O-N 3.4Å; R324-R328 WeakPolarHBondContact O-CG 3.45Å; R324-R328 PolarHBondContact O-N 2.8Å; R324-R328 VanDerWaalsContact O-N 3.07Å
325	S	88.3	Confident	80.7	Confident	43 Å²	43	74.3 Å²	74.3	30%	0.301	38%	0.381	S	S	.	.	H	α-helix	trans	-63	-43.5	176	-174.5	0	0	0	0	111.8	D321 R322 L323 R328 K329	D321-S325 WeakPolarHBondContact O-CB 3.37Å; D321-S325 PolarHBondContact O-N 2.76Å; R322-S325 WeakPolarHBondContact O-CB 3.27Å; R322-S325 PolarHBondContact O-N 2.77Å; L323-S325 VanDerWaalsContact C-N 3.31Å; L323-S325 PolarHBondContact O-N 2.86Å; S325-R328 PolarHBondContact O-N 3.45Å; S325-K329 PolarHBondContact O-N 3.34Å; S325-K329 VanDerWaalsContact O-N 3.12Å
326	A	88.2	Confident	80.5	Confident	7 Å²	7	78.7 Å²	78.7	6%	0.058	40%	0.403	C	S	.	.	H	α-helix	trans	-63.4	-45	177.5	0	0	0	0	0	112.1	Y68 Q72 R322 L323 R328 K329 G330	Y68-A326 HydrophobicContact CE1-CB 4.01Å; Q72-A326 HydrophobicContact CG-CB 4.08Å; R322-A326 WeakPolarHBondContact O-CB 3.28Å; R322-A326 PolarHBondContact O-N 2.72Å; L323-A326 PolarHBondContact O-N 2.73Å; A326-R328 VanDerWaalsContact C-N 3.31Å; A326-R328 PolarHBondContact O-N 3.32Å; A326-K329 PolarHBondContact O-N 3.41Å; A326-G330 PolarHBondContact O-N 3.38Å
327	L	88.8	Confident	80.2	Confident	109 Å²	109	83.1 Å²	83.1	57%	0.571	42%	0.423	S	S	*	.	H	α-helix	trans	-62.6	-37.3	177.4	-68.8	172.8	0	0	0	112.2	L323 G330 H331	L323-L327 HydrophobicContact CD1-CD1 4.33Å; L323-L327 HydrophobicContact CD1-CG 4.35Å; L323-L327 HydrophobicContact CG-CD1 4.24Å; L323-L327 WeakPolarHBondContact O-CG 3.35Å; L323-L327 PolarHBondContact O-N 2.87Å; L327-G330 PolarHBondContact O-N 3.36Å; L327-H331 PolarHBondContact O-N 3.12Å
328	R	85.9	Confident	79.9	Confident	200 Å²	200	86.3 Å²	86.3	76%	0.755	44%	0.44	S	S	*	.	H	α-helix	trans	-67.5	-32.7	175.2	-75	175.2	-179.6	179.3	-1.7	113.3	R324 S325 A326 G330	R324-R328 WeakPolarHBondContact O-CG 3.45Å; R324-R328 PolarHBondContact O-N 2.8Å; R324-R328 VanDerWaalsContact O-N 3.07Å; S325-R328 PolarHBondContact O-N 3.45Å; A326-R328 VanDerWaalsContact C-N 3.31Å; A326-R328 PolarHBondContact O-N 3.32Å; R328-G330 VanDerWaalsContact C-N 3.27Å
329	K	72.4	Confident	79.6	Confident	140 Å²	140	89.7 Å²	89.7	61%	0.609	46%	0.457	S	S	*	.	H	α-helix	trans	-72.2	-22	173.8	-71.4	-179.4	-179.9	-177.3	0	113	S325 A326	S325-K329 PolarHBondContact O-N 3.34Å; S325-K329 VanDerWaalsContact O-N 3.12Å; A326-K329 PolarHBondContact O-N 3.41Å
330	G	59.2	Low	79	Confident	56 Å²	56	96 Å²	96	58%	0.577	49%	0.489	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.1	-1.1	178.8	0	0	0	0	0	114.9	A326 L327 R328	A326-G330 PolarHBondContact O-N 3.38Å; L327-G330 PolarHBondContact O-N 3.36Å; R328-G330 VanDerWaalsContact C-N 3.27Å
331	H	47.2	Very low	78.1	Confident	156 Å²	156	97.8 Å²	97.8	72%	0.722	50%	0.503	S	S	*	.			trans	-105.1	105.3	169.4	-83.3	47.3	0	0	0	108	L327	L327-H331 PolarHBondContact O-N 3.12Å
332	P	46.5	Very low	77.1	Confident	200 Å²	200	100.9 Å²	100.9	100%	1.299	52%	0.518	S	S	*	.			trans	-63.1	0	176	26.2	-32.5	0	0	0	112.9

Retrieved 332 of 332 residues in 88.6 ms (Link to these results)

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