A0A096N2F1_PAPAN Loading...

Natural resistance-associated macrophage protein 1

Macrophage-specific antiporter that fluxes metal ions in either direction against a proton gradient. Localized to late endosomal lysosomal membranes, delivers bivalent cations from the cytosol into these acidic compartments where they may directly affect antimicrobial activity. Involved in iron metabolism and host natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

AlphaFold DB , UniProt , Accession A0A096N2F1, Species PAPAN (Papio anubis, Olive baboon), Gene SLC11A1, Length 547 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.3	Very low	29.5	Very low	229 Å²	229	154.2 Å²	154.2	100%	1.128	86%	0.858	S	S	*	*				0	92.9	0	-75.1	167.7	168.3	0	0	106.6
2	T	31.6	Very low	29.1	Very low	140 Å²	140	162.9 Å²	162.9	86%	0.859	87%	0.868	S	S	*	*				73	114.7	112.7	53.2	0	0	0	0	111.8
3	G	28.6	Very low	28.8	Very low	76 Å²	76	158.5 Å²	158.5	78%	0.784	86%	0.858	S	S	*	*			cis	113.5	109	38.3	0	0	0	0	0	106.9
4	D	28.9	Very low	28.5	Very low	127 Å²	127	155.1 Å²	155.1	68%	0.679	85%	0.852	S	S	*	*				100.7	131	82.8	-157.5	21.8	0	0	0	114.3
5	K	31	Very low	28.3	Very low	186 Å²	186	160.3 Å²	160.3	81%	0.809	86%	0.856	S	S	*	*			trans	64.5	132	151.3	-83.5	157.6	-156.9	153.5	0	126.3
6	G	26.8	Very low	28.1	Very low	75 Å²	75	154.2 Å²	154.2	77%	0.773	84%	0.843	S	S	*	*				146.1	138.4	126.4	0	0	0	0	0	117.4
7	P	35.9	Very low	27.9	Very low	137 Å²	137	152.2 Å²	152.2	89%	0.89	84%	0.843	S	S	*	*			trans	-110.8	165.4	-138.3	39	-30.3	0	0	0	118.5
8	Q	27.9	Very low	27.8	Very low	190 Å²	190	152.8 Å²	152.8	89%	0.888	84%	0.843	S	S	*	*	P	Polyproline II helix	trans	-69.8	139.8	176.1	-72.1	171.4	-21.1	0	0	113.7
9	R	26.8	Very low	27.6	Very low	253 Å²	253	150.6 Å²	150.6	96%	0.955	84%	0.839	S	S	*	*	P	Polyproline II helix	trans	-73.5	126.9	175.6	-92.7	-179.9	-179.1	-172.1	0.2	111.9
10	L	26.3	Very low	27.5	Very low	175 Å²	175	148.3 Å²	148.3	92%	0.916	83%	0.834	S	S	*	*	P	Polyproline II helix	trans	-66.3	129.5	171.4	-83.4	115.6	0	0	0	112.9
11	S	26.9	Very low	27.5	Very low	108 Å²	108	149.7 Å²	149.7	76%	0.755	84%	0.838	S	S	*	*	P	Polyproline II helix	trans	-83.2	136.6	161	63.5	0	0	0	0	110.5	S13	S11-S13 PolarHBondContact O-N 3.27Å
12	R	24.4	Very low	27.1	Very low	259 Å²	259	145 Å²	145	98%	0.977	82%	0.823	S	S	*	*	P	Polyproline II helix	trans	-56.2	119.3	175.1	-87.6	174.1	168.4	164.6	-4.7	111.4
13	S	25.5	Very low	26.8	Very low	106 Å²	106	143.5 Å²	143.5	74%	0.741	82%	0.818	S	S	*	*	P	Polyproline II helix	trans	-81	136.9	171.4	-179	0	0	0	0	111.2	S11	S11-S13 PolarHBondContact O-N 3.27Å
14	S	24.2	Very low	26.9	Very low	111 Å²	111	145.6 Å²	145.6	78%	0.776	82%	0.818	S	S	*	*	P	Polyproline II helix	trans	-52.5	136	162.3	-165.3	0	0	0	0	110.8
15	Y	26	Very low	26.8	Very low	232 Å²	232	142 Å²	142	91%	0.91	81%	0.811	S	S	*	*	P	Polyproline II helix	trans	-87.7	118.3	173.6	-91.8	-86.1	0	0	0	110
16	G	25.1	Very low	26.7	Very low	63 Å²	63	139.4 Å²	139.4	65%	0.649	81%	0.813	S	S	*	*	P	Polyproline II helix	trans	-80.1	159.2	174.2	0	0	0	0	0	113.7
17	S	24.7	Very low	26.8	Very low	121 Å²	121	144.3 Å²	144.3	85%	0.846	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-51.8	133.5	168.7	49.3	0	0	0	0	114.2
18	I	25.5	Very low	26.5	Very low	162 Å²	162	146.8 Å²	146.8	83%	0.831	82%	0.815	S	S	*	*			trans	-127.9	112.6	155	-64.3	178.2	0	0	0	108.2
19	S	24.3	Very low	26.5	Very low	111 Å²	111	141.5 Å²	141.5	78%	0.776	80%	0.804	S	S	*	*			trans	-74.9	127.4	162.4	45.4	0	0	0	0	110.2
20	S	25.8	Very low	26.9	Very low	105 Å²	105	134.3 Å²	134.3	73%	0.734	79%	0.79	S	S	*	*			trans	-129.5	117.9	155.7	50.3	0	0	0	0	109.1
21	L	26.7	Very low	27.5	Very low	177 Å²	177	130.3 Å²	130.3	93%	0.927	78%	0.775	S	S	*	*			trans	-70.5	122.2	168.3	-83.6	102.2	0	0	0	109
22	T	25.8	Very low	28	Very low	130 Å²	130	134.9 Å²	134.9	80%	0.798	78%	0.776	S	S	*	*			trans	-135.5	125	156.6	-33.4	0	0	0	0	107.1
23	S	26.3	Very low	29.3	Very low	110 Å²	110	125.3 Å²	125.3	77%	0.769	74%	0.742	S	S	*	*			trans	-48.9	138.8	-177.9	-63.4	0	0	0	0	112.8	G25	S23-G25 PolarHBondContact O-N 3.47Å; S23-G25 VanDerWaalsContact O-N 3.08Å
24	P	30.3	Very low	30.5	Very low	120 Å²	120	121.9 Å²	121.9	78%	0.779	72%	0.717	S	S	*	*			trans	-74.1	102.9	169.3	29.1	-28.8	0	0	0	108.5
25	G	27.3	Very low	31.8	Very low	51 Å²	51	117 Å²	117	53%	0.526	68%	0.681	S	S	.	*			trans	-56.6	150.9	150.2	0	0	0	0	0	108.4	S23 Q27	S23-G25 PolarHBondContact O-N 3.47Å; S23-G25 VanDerWaalsContact O-N 3.08Å; G25-Q27 PolarHBondContact O-N 3.44Å
26	P	29.1	Very low	33.3	Very low	131 Å²	131	107.7 Å²	107.7	85%	0.851	65%	0.647	S	S	*	*			trans	-57.7	105.3	-174.2	22.7	-31	0	0	0	109	Q28	P26-Q28 PolarHBondContact O-N 3.47Å
27	Q	28.3	Very low	34.6	Very low	178 Å²	178	108.7 Å²	108.7	83%	0.832	64%	0.644	S	S	*	*			trans	-59.3	107	166.5	-77	175.5	-16.4	0	0	105.1	G25 A29	G25-Q27 PolarHBondContact O-N 3.44Å; Q27-A29 PolarHBondContact O-N 3.36Å
28	Q	29.7	Very low	36.2	Very low	189 Å²	189	109.6 Å²	109.6	88%	0.883	64%	0.635	S	S	*	*			trans	-55.9	103	159.1	-90.9	170	-33	0	0	105.6	P26	P26-Q28 PolarHBondContact O-N 3.47Å
29	A	27.7	Very low	38.4	Very low	79 Å²	79	106.3 Å²	106.3	65%	0.653	62%	0.615	S	S	*	*	P	Polyproline II helix	trans	-48.7	130.3	168.6	0	0	0	0	0	106.9	Q27	Q27-A29 PolarHBondContact O-N 3.36Å
30	P	35	Very low	40.7	Very low	103 Å²	103	102.2 Å²	102.2	67%	0.669	58%	0.584	S	S	*	*	P	Polyproline II helix	trans	-53	136.4	171.7	22.3	-30.6	0	0	0	107.2	R32	P30-R32 PolarHBondContact O-N 3.22Å
31	P	39.3	Very low	42.8	Very low	91 Å²	91	101.5 Å²	101.5	59%	0.591	58%	0.577	S	S	*	*	P	Polyproline II helix	trans	-53.5	119.2	179.7	19.7	-29.2	0	0	0	107.9	E33	P31-E33 PolarHBondContact O-N 3.22Å
32	R	38.1	Very low	45	Very low	204 Å²	204	95.3 Å²	95.3	77%	0.77	54%	0.544	S	S	*	.			trans	-54	100.4	-178	-85	177.5	161.1	175.1	-6.2	110	P30 T34 R394	P30-R32 PolarHBondContact O-N 3.22Å; R32-T34 VanDerWaalsContact C-N 3.33Å; R32-T34 PolarHBondContact O-N 3.2Å; R32-T34 PolarHBondContact O-OG1 3.08Å; R32-T34 VanDerWaalsContact O-OG1 3.11Å; R32-R394 PolarHBondContact O-NE 3.47Å; R32-R394 PolarHBondContact O-NH2 3.09Å
33	E	50.8	Low	46.9	Very low	57 Å²	57	90.9 Å²	90.9	27%	0.266	52%	0.518	S	S	.	.			trans	-75.1	85.4	167.8	-77.9	175	-164	0	0	108.3	P31 Y35 L36 S37	P31-E33 PolarHBondContact O-N 3.22Å; E33-Y35 PolarHBondContact O-N 2.86Å; E33-Y35 VanDerWaalsContact O-N 3.13Å; E33-L36 PolarHBondContact O-N 3.35Å; E33-S37 WeakPolarHBondContact O-CB 3.42Å; E33-S37 PolarHBondContact O-N 2.77Å; E33-S37 VanDerWaalsContact O-N 3.09Å; E33-S37 PolarHBondContact O-OG 2.77Å
34	T	51.2	Low	48.4	Very low	35 Å²	35	93.2 Å²	93.2	22%	0.215	52%	0.522	C	S	.	.	H	α-helix	trans	-68	-22.1	-159.2	-35.1	0	0	0	0	113.2	R32 R394	R32-T34 VanDerWaalsContact C-N 3.33Å; R32-T34 PolarHBondContact O-N 3.2Å; R32-T34 PolarHBondContact O-OG1 3.08Å; R32-T34 VanDerWaalsContact O-OG1 3.11Å; T34-R394 PolarHBondContact OG1-NH1 3.25Å; T34-R394 PolarHBondContact OG1-NH2 2.68Å
35	Y	51.3	Low	49.9	Very low	8 Å²	8	89.7 Å²	89.7	3%	0.031	50%	0.498	C	S	.	.	H	α-helix	trans	-75	-42.9	-179.7	-115.2	-104.7	0	0	0	115.6	E33 L64 D185 L189 L192 Y378	E33-Y35 PolarHBondContact O-N 2.86Å; E33-Y35 VanDerWaalsContact O-N 3.13Å; Y35-L64 HydrophobicContact CE1-CD2 4.13Å; Y35-D185 WeakPolarHBondContact CD2-OD1 3.25Å; Y35-D185 WeakPolarHBondContact CE2-OD1 3.16Å; Y35-L189 HydrophobicContact CD1-CD1 3.7Å; Y35-L189 HydrophobicContact CD1-CG 4.4Å; Y35-L189 HydrophobicContact CE1-CD1 3.95Å; Y35-L189 HydrophobicContact CE1-CG 4.17Å; Y35-L189 HydrophobicContact CG-CD1 4.36Å; Y35-L189 WeakPolarHBondContact O-CD1 3.31Å; Y35-L192 HydrophobicContact CE2-CD1 3.58Å; Y35-L192 WeakPolarHBondContact OH-CD1 3.13Å; Y35-L192 WeakPolarHBondContact OH-CD2 3.42Å; Y35-L192 VanDerWaalsContact OH-CG 3.23Å; Y35-L192 WeakPolarHBondContact OH-CG 2.93Å; Y35-Y378 HydrophobicContact CD1-CD1 4.46Å; Y35-Y378 HydrophobicContact CD1-CE1 4.07Å; Y35-Y378 HydrophobicContact CD2-CD1 4.41Å; Y35-Y378 AromaticContact CD2-CE1 3.37Å; Y35-Y378 HydrophobicContact CD2-CE1 3.37Å; Y35-Y378 AromaticContact CD2-CZ 3.54Å; Y35-Y378 WeakPolarHBondContact CD2-OH 3.36Å; Y35-Y378 HydrophobicContact CE1-CE1 4.19Å; Y35-Y378 HydrophobicContact CE1-CE2 4.23Å; Y35-Y378 AromaticContact CE1-CZ 3.98Å; Y35-Y378 AromaticContact CE2-CE1 3.56Å; Y35-Y378 HydrophobicContact CE2-CE1 3.56Å; Y35-Y378 HydrophobicContact CE2-CE2 4.04Å; Y35-Y378 AromaticContact CE2-CZ 3.17Å; Y35-Y378 WeakPolarHBondContact CE2-OH 3.01Å; Y35-Y378 HydrophobicContact CG-CD1 4.27Å; Y35-Y378 AromaticContact CG-CE1 3.62Å; Y35-Y378 HydrophobicContact CG-CE1 3.62Å; Y35-Y378 AromaticContact CZ-CE1 3.91Å; Y35-Y378 AromaticContact CZ-CE2 3.75Å; Y35-Y378 AromaticContact CZ-CZ 3.35Å; Y35-Y378 VanDerWaalsContact CZ-OH 3.29Å; Y35-Y378 PolarHBondContact OH-OH 3.11Å
36	L	56.8	Low	51.4	Low	36 Å²	36	95.6 Å²	95.6	19%	0.188	51%	0.509	C	S	.	.	H	α-helix	trans	-101.1	-7.8	-178.9	-69.8	179.7	0	0	0	113.2	E33 K262 F382	E33-L36 PolarHBondContact O-N 3.35Å; L36-K262 HydrophobicContact CD2-CB 4.14Å; L36-F382 HydrophobicContact CD1-CE1 3.58Å; L36-F382 HydrophobicContact CD1-CZ 4.22Å; L36-F382 HydrophobicContact CG-CE1 4.19Å; L36-F382 HydrophobicContact CG-CZ 4.39Å
37	S	53.8	Low	52.5	Low	85 Å²	85	94.4 Å²	94.4	59%	0.594	50%	0.501	S	S	*	.	H	α-helix	trans	-71.9	-29.1	-179.6	-67.3	0	0	0	0	113.3	E33	E33-S37 WeakPolarHBondContact O-CB 3.42Å; E33-S37 PolarHBondContact O-N 2.77Å; E33-S37 VanDerWaalsContact O-N 3.09Å; E33-S37 PolarHBondContact O-OG 2.77Å
38	E	58	Low	53.9	Low	140 Å²	140	89.8 Å²	89.8	65%	0.654	50%	0.501	S	S	*	.	S	Bend	trans	-114.6	89	179.3	-163.5	171.8	-156.2	0	0	109
39	K	72	Confident	55.6	Low	93 Å²	93	85 Å²	85	40%	0.404	49%	0.485	S	S	.	.	P	Polyproline II helix	trans	-76.5	145.8	179.3	-59.8	178.2	-176.6	170.1	0	110.4	P41 S263 E265	K39-P41 WeakPolarHBondContact O-CD 3.42Å; K39-S263 WeakPolarHBondContact CA-O 3.49Å; K39-E265 HydrophobicContact CB-CG 3.56Å; K39-E265 HydrophobicContact CD-CG 3.52Å; K39-E265 HydrophobicContact CG-CG 4.2Å
40	I	72.3	Confident	57.8	Low	25 Å²	25	86.6 Å²	86.6	13%	0.128	48%	0.478	C	S	.	.	B	Isolated β-bridge	trans	-84.4	121.5	178.7	-67.5	158.5	0	0	0	109.2	L189 R190 S263 R264 E265	I40-L189 HydrophobicContact CD1-CD2 3.46Å; I40-L189 VanDerWaalsContact CD1-CD2 3.46Å; I40-L189 HydrophobicContact CG1-CD2 4.5Å; I40-R190 HydrophobicContact CD1-CG 4.01Å; I40-R190 VanDerWaalsContact CD1-NE 3.34Å; I40-S263 PolarHBondContact N-O 2.64Å; I40-R264 VanDerWaalsContact CD1-CZ 3.43Å; I40-E265 PolarHBondContact O-N 2.89Å
41	P	68.9	Low	60	Low	90 Å²	90	82.9 Å²	82.9	58%	0.584	45%	0.454	S	S	*	.	P	Polyproline II helix	trans	-70.2	137.9	176	28.6	-33.8	0	0	0	110.2	K39	K39-P41 WeakPolarHBondContact O-CD 3.42Å
42	I	72.5	Confident	62	Low	46 Å²	46	84.6 Å²	84.6	24%	0.236	46%	0.458	C	S	.	.	P	Polyproline II helix	trans	-86.2	131.9	178.6	-57.2	169.4	0	0	0	108.6	D44 F58 E265 I266	I42-D44 PolarHBondContact O-N 3.39Å; I42-F58 HydrophobicContact CD1-CE1 3.78Å; I42-F58 HydrophobicContact CD1-CE2 4.07Å; I42-F58 HydrophobicContact CD1-CZ 3.34Å; I42-F58 HydrophobicContact CG1-CE1 4.46Å; I42-F58 HydrophobicContact CG1-CE2 4.38Å; I42-F58 HydrophobicContact CG1-CZ 4.05Å; I42-F58 HydrophobicContact CG2-CE2 3.89Å; I42-F58 HydrophobicContact CG2-CZ 4.23Å; I42-E265 WeakPolarHBondContact CD1-O 3.49Å; I42-I266 HydrophobicContact CD1-CG1 4.12Å
43	P	66.6	Low	64	Low	38 Å²	38	84 Å²	84	25%	0.247	46%	0.455	C	S	.	.	P	Polyproline II helix	trans	-66.6	127.1	175.8	24.6	-31	0	0	0	111.4	T45 K54 A57	P43-T45 PolarHBondContact O-N 3.22Å; P43-T45 VanDerWaalsContact O-N 3.08Å; P43-K54 HydrophobicContact CG-CG 4.16Å; P43-K54 WeakPolarHBondContact O-CE 3.38Å; P43-A57 HydrophobicContact CG-CB 4.15Å
44	D	58.7	Low	65.3	Low	159 Å²	159	81.7 Å²	81.7	85%	0.85	44%	0.444	S	S	*	.			trans	-67	104	174	-72.2	-40.6	0	0	0	110.4	I42	I42-D44 PolarHBondContact O-N 3.39Å
45	T	60.1	Low	66.8	Low	45 Å²	45	81.1 Å²	81.1	28%	0.276	44%	0.44	S	S	.	.			trans	-118.6	154.5	167.1	70.4	0	0	0	0	109.7	P43 K54	P43-T45 PolarHBondContact O-N 3.22Å; P43-T45 VanDerWaalsContact O-N 3.08Å; T45-K54 HydrophobicContact CG2-CG 4.4Å; T45-K54 PolarHBondContact O-NZ 3.37Å; T45-K54 WeakPolarHBondContact OG1-CD 3.26Å; T45-K54 WeakPolarHBondContact OG1-CE 3.2Å; T45-K54 PolarHBondContact OG1-NZ 3.19Å
46	K	58.6	Low	68.4	Low	176 Å²	176	89.8 Å²	89.8	77%	0.765	47%	0.473	S	S	*	.			trans	-45	131.6	-178.1	-67.6	-176.5	-179.5	-179.6	0	111.4	G48	K46-G48 PolarHBondContact O-N 3.15Å
47	P	53.4	Low	69.4	Low	106 Å²	106	88.6 Å²	88.6	69%	0.688	47%	0.468	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64	133.8	179.3	23.9	-31	0	0	0	110.3
48	G	58	Low	70.7	Confident	81 Å²	81	84.8 Å²	84.8	84%	0.835	44%	0.441	S	S	*	.	T	Hydrogen-bonded Turn	trans	103.6	-6	171.4	0	0	0	0	0	117.1	K46	K46-G48 PolarHBondContact O-N 3.15Å
49	T	65	Low	72.1	Confident	89 Å²	89	79.5 Å²	79.5	55%	0.546	42%	0.418	S	S	.	.	S	Bend	trans	-110.9	127.9	174.3	50.1	0	0	0	0	111.4	S51	T49-S51 PolarHBondContact O-N 3.48Å
50	F	73.1	Confident	72.7	Confident	112 Å²	112	75.2 Å²	75.2	49%	0.491	40%	0.4	S	S	.	.			trans	-57.9	127.4	172.1	177.7	-100.6	0	0	0	110.2	L52 L55 M279 Y280 I283	F50-L52 HydrophobicContact CE1-CD2 3.71Å; F50-L52 HydrophobicContact CE1-CG 4.21Å; F50-L52 HydrophobicContact CZ-CD2 4.1Å; F50-L55 HydrophobicContact CZ-CD2 4.1Å; F50-M279 HydrophobicContact CD2-CE 4.36Å; F50-Y280 AromaticContact CD2-CE1 3.89Å; F50-Y280 HydrophobicContact CD2-CE1 3.89Å; F50-Y280 HydrophobicContact CE2-CD1 4.44Å; F50-Y280 AromaticContact CE2-CE1 3.9Å; F50-Y280 HydrophobicContact CE2-CE1 3.9Å; F50-I283 HydrophobicContact CD2-CD1 4.4Å; F50-I283 HydrophobicContact CE2-CD1 3.86Å
51	S	81.5	Confident	73.4	Confident	24 Å²	24	74.1 Å²	74.1	17%	0.168	40%	0.395	C	S	.	.			trans	-127	120.5	-178.5	174.4	0	0	0	0	110.5	T49 R53 K54 L55 Y280	T49-S51 PolarHBondContact O-N 3.48Å; S51-R53 PolarHBondContact O-N 3.28Å; S51-R53 PolarHBondContact OG-N 3.14Å; S51-K54 WeakPolarHBondContact O-CB 3.35Å; S51-K54 PolarHBondContact O-N 2.93Å; S51-K54 VanDerWaalsContact O-N 3.09Å; S51-K54 PolarHBondContact OG-N 3.42Å; S51-L55 PolarHBondContact O-N 3.09Å; S51-Y280 PolarHBondContact N-OH 3.2Å; S51-Y280 VanDerWaalsContact N-OH 3.14Å
52	L	81.6	Confident	74.4	Confident	128 Å²	128	69.8 Å²	69.8	67%	0.67	37%	0.367	S	S	*	.	H	α-helix	trans	-60.7	-30.6	174.8	-69.2	173	0	0	0	112.2	F50 L55 W56	F50-L52 HydrophobicContact CE1-CD2 3.71Å; F50-L52 HydrophobicContact CE1-CG 4.21Å; F50-L52 HydrophobicContact CZ-CD2 4.1Å; L52-L55 HydrophobicContact CD2-CD2 4.33Å; L52-L55 PolarHBondContact O-N 3.44Å; L52-W56 PolarHBondContact O-N 2.82Å
53	R	79.6	Confident	75.2	Confident	190 Å²	190	70.2 Å²	70.2	72%	0.717	37%	0.367	S	S	*	.	H	α-helix	trans	-67.6	-38.2	175.4	-168.5	179.4	-170.6	-176.4	3.1	111.9	S51 A57	S51-R53 PolarHBondContact O-N 3.28Å; S51-R53 PolarHBondContact OG-N 3.14Å; R53-A57 PolarHBondContact O-N 3.15Å
54	K	79.5	Confident	76.3	Confident	10 Å²	10	68.6 Å²	68.6	4%	0.043	36%	0.356	C	S	.	.	H	α-helix	trans	-68.1	-44.7	171.9	-82.3	-175.4	164.3	176.4	0	110.5	P43 T45 S51 W56 A57 F58 E276 Y280	P43-K54 HydrophobicContact CG-CG 4.16Å; P43-K54 WeakPolarHBondContact O-CE 3.38Å; T45-K54 HydrophobicContact CG2-CG 4.4Å; T45-K54 PolarHBondContact O-NZ 3.37Å; T45-K54 WeakPolarHBondContact OG1-CD 3.26Å; T45-K54 WeakPolarHBondContact OG1-CE 3.2Å; T45-K54 PolarHBondContact OG1-NZ 3.19Å; S51-K54 WeakPolarHBondContact O-CB 3.35Å; S51-K54 PolarHBondContact O-N 2.93Å; S51-K54 VanDerWaalsContact O-N 3.09Å; S51-K54 PolarHBondContact OG-N 3.42Å; K54-W56 VanDerWaalsContact C-N 3.28Å; K54-W56 PolarHBondContact O-N 3.39Å; K54-A57 WeakPolarHBondContact O-CA 3.41Å; K54-A57 VanDerWaalsContact O-CB 3.31Å; K54-A57 WeakPolarHBondContact O-CB 3.49Å; K54-A57 PolarHBondContact O-N 3.32Å; K54-F58 VanDerWaalsContact O-CD2 3.27Å; K54-F58 WeakPolarHBondContact O-CD2 3.23Å; K54-F58 PolarHBondContact O-N 3.16Å; K54-E276 WeakPolarHBondContact CD-OE1 3.32Å; K54-E276 IonicContact NZ-OE1 2.77Å; K54-E276 PolarHBondContact NZ-OE1 2.94Å; K54-E276 IonicContact NZ-OE2 3.22Å; K54-E276 PolarHBondContact NZ-OE2 2.97Å; K54-Y280 HydrophobicContact CB-CE1 4.27Å; K54-Y280 HydrophobicContact CB-CE2 4.1Å; K54-Y280 HydrophobicContact CD-CE2 4.16Å
55	L	82.9	Confident	77.8	Confident	22 Å²	22	61 Å²	61	12%	0.115	32%	0.315	C	S	.	.	H	α-helix	trans	-54.8	-45.4	176.2	-175.6	69.3	0	0	0	111.3	F50 S51 L52 A57 F58 T59 Y280 I283	F50-L55 HydrophobicContact CZ-CD2 4.1Å; S51-L55 PolarHBondContact O-N 3.09Å; L52-L55 HydrophobicContact CD2-CD2 4.33Å; L52-L55 PolarHBondContact O-N 3.44Å; L55-A57 VanDerWaalsContact C-N 3.3Å; L55-A57 PolarHBondContact O-N 3.03Å; L55-F58 PolarHBondContact O-N 3.29Å; L55-F58 VanDerWaalsContact O-N 3.17Å; L55-T59 WeakPolarHBondContact O-CB 3.38Å; L55-T59 PolarHBondContact O-N 2.93Å; L55-T59 PolarHBondContact O-OG1 3.18Å; L55-Y280 HydrophobicContact CB-CD1 4.14Å; L55-Y280 HydrophobicContact CB-CE1 4.17Å; L55-Y280 HydrophobicContact CD1-CD1 3.82Å; L55-I283 HydrophobicContact CD1-CB 4.38Å; L55-I283 HydrophobicContact CD1-CG2 3.93Å
56	W	83.4	Confident	79.3	Confident	191 Å²	191	58.9 Å²	58.9	72%	0.723	30%	0.303	S	S	*	.	H	α-helix	trans	-61.1	-37.3	175.2	-168.9	-94.3	0	0	0	113	L52 K54 F58 T59 R190	L52-W56 PolarHBondContact O-N 2.82Å; K54-W56 VanDerWaalsContact C-N 3.28Å; K54-W56 PolarHBondContact O-N 3.39Å; W56-F58 VanDerWaalsContact C-N 3.35Å; W56-T59 PolarHBondContact O-N 3.23Å; W56-R190 PolarHBondContact O-NH2 3.04Å
57	A	79.3	Confident	80.8	Confident	11 Å²	11	50.5 Å²	50.5	9%	0.091	27%	0.266	C	S	.	.	H	α-helix	trans	-64.6	-38	175.1	0	0	0	0	0	112.4	P43 R53 K54 L55 R190 R264	P43-A57 HydrophobicContact CG-CB 4.15Å; R53-A57 PolarHBondContact O-N 3.15Å; K54-A57 WeakPolarHBondContact O-CA 3.41Å; K54-A57 VanDerWaalsContact O-CB 3.31Å; K54-A57 WeakPolarHBondContact O-CB 3.49Å; K54-A57 PolarHBondContact O-N 3.32Å; L55-A57 VanDerWaalsContact C-N 3.3Å; L55-A57 PolarHBondContact O-N 3.03Å; A57-R190 VanDerWaalsContact C-NH2 3.35Å; A57-R190 VanDerWaalsContact CA-NH2 3.3Å; A57-R190 PolarHBondContact O-NH2 3.23Å; A57-R264 PolarHBondContact O-NE 3.16Å
58	F	80.9	Confident	82.4	Confident	5 Å²	5	45.5 Å²	45.5	2%	0.022	23%	0.233	C	C	.	.	H	α-helix	trans	-77.5	-31.5	175.4	-78.1	-79.7	0	0	0	113.1	I42 K54 L55 W56 G60 P61 R264 A277 Y280 F281 E284	I42-F58 HydrophobicContact CD1-CE1 3.78Å; I42-F58 HydrophobicContact CD1-CE2 4.07Å; I42-F58 HydrophobicContact CD1-CZ 3.34Å; I42-F58 HydrophobicContact CG1-CE1 4.46Å; I42-F58 HydrophobicContact CG1-CE2 4.38Å; I42-F58 HydrophobicContact CG1-CZ 4.05Å; I42-F58 HydrophobicContact CG2-CE2 3.89Å; I42-F58 HydrophobicContact CG2-CZ 4.23Å; K54-F58 VanDerWaalsContact O-CD2 3.27Å; K54-F58 WeakPolarHBondContact O-CD2 3.23Å; K54-F58 PolarHBondContact O-N 3.16Å; L55-F58 PolarHBondContact O-N 3.29Å; L55-F58 VanDerWaalsContact O-N 3.17Å; W56-F58 VanDerWaalsContact C-N 3.35Å; F58-G60 PolarHBondContact O-N 3.36Å; F58-P61 VanDerWaalsContact O-CD 3.27Å; F58-P61 WeakPolarHBondContact O-CD 3.42Å; F58-R264 HydrophobicContact CD1-CB 4.47Å; F58-R264 HydrophobicContact CD1-CG 4.24Å; F58-R264 HydrophobicContact CE1-CB 4.44Å; F58-R264 PolarHBondContact O-NE 3.47Å; F58-A277 HydrophobicContact CE1-CB 4.02Å; F58-A277 HydrophobicContact CZ-CB 4.21Å; F58-Y280 AromaticContact CD2-CD2 3.81Å; F58-Y280 HydrophobicContact CD2-CD2 3.81Å; F58-Y280 AromaticContact CD2-CG 3.85Å; F58-Y280 HydrophobicContact CD2-CG 3.85Å; F58-Y280 AromaticContact CE2-CD2 3.69Å; F58-Y280 HydrophobicContact CE2-CD2 3.69Å; F58-Y280 HydrophobicContact CE2-CE2 4.29Å; F58-Y280 HydrophobicContact CE2-CG 4.21Å; F58-Y280 HydrophobicContact CG-CG 4.39Å; F58-Y280 HydrophobicContact CZ-CD2 4.4Å; F58-F281 HydrophobicContact CD1-CE1 4.14Å; F58-F281 HydrophobicContact CD1-CE2 4.05Å; F58-F281 AromaticContact CD1-CZ 3.84Å; F58-F281 HydrophobicContact CD1-CZ 3.84Å; F58-F281 HydrophobicContact CE1-CE2 4.16Å; F58-F281 HydrophobicContact CE1-CZ 4.29Å; F58-E284 VanDerWaalsContact O-OE2 3.14Å
59	T	85.9	Confident	84	Confident	28 Å²	28	41.7 Å²	41.7	17%	0.172	19%	0.194	C	C	.	.			trans	-54.9	133	-179.1	-57.1	0	0	0	0	111.5	L55 W56 F63 R190 R264 E284	L55-T59 WeakPolarHBondContact O-CB 3.38Å; L55-T59 PolarHBondContact O-N 2.93Å; L55-T59 PolarHBondContact O-OG1 3.18Å; W56-T59 PolarHBondContact O-N 3.23Å; T59-F63 HydrophobicContact CG2-CD2 3.66Å; T59-F63 HydrophobicContact CG2-CE2 3.57Å; T59-R190 PolarHBondContact O-NH1 3Å; T59-R264 PolarHBondContact O-NH2 3.09Å; T59-E284 WeakPolarHBondContact CA-OE1 3.31Å
60	G	85.8	Confident	85.3	Confident	3 Å²	3	37.5 Å²	37.5	3%	0.031	17%	0.168	C	C	.	.	S	Bend	trans	146.3	-71.9	-176.9	0	0	0	0	0	112.5	F58 G62 F63 L64 E193 E284	F58-G60 PolarHBondContact O-N 3.36Å; G60-G62 VanDerWaalsContact C-N 3.29Å; G60-G62 PolarHBondContact O-N 2.84Å; G60-F63 PolarHBondContact O-N 2.96Å; G60-L64 VanDerWaalsContact O-CD1 3.31Å; G60-L64 WeakPolarHBondContact O-CD1 3.23Å; G60-L64 PolarHBondContact O-N 2.91Å; G60-E193 VanDerWaalsContact CA-CD 3.41Å; G60-E193 VanDerWaalsContact CA-OE1 3.3Å; G60-E193 WeakPolarHBondContact CA-OE1 3.34Å; G60-E284 WeakPolarHBondContact CA-OE1 3.3Å; G60-E284 PolarHBondContact N-OE1 3.03Å
61	P	86.8	Confident	86.2	Confident	2 Å²	2	32.2 Å²	32.2	1%	0.013	15%	0.145	C	C	.	.	H	α-helix	trans	-51.7	-40.5	-176.9	-32.4	41.1	0	0	0	114.9	F58 M65 L260 F281	F58-P61 VanDerWaalsContact O-CD 3.27Å; F58-P61 WeakPolarHBondContact O-CD 3.42Å; P61-M65 WeakPolarHBondContact O-CB 3.27Å; P61-M65 PolarHBondContact O-N 3.4Å; P61-L260 HydrophobicContact CB-CB 3.89Å; P61-F281 HydrophobicContact CB-CE1 4.24Å; P61-F281 HydrophobicContact CG-CE1 4.02Å
62	G	89.3	Confident	86.6	Confident	0 Å²	0	31.1 Å²	31.1	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-67.7	-38.7	177.8	0	0	0	0	0	112.6	G60 M65 S66 E284 A288	G60-G62 VanDerWaalsContact C-N 3.29Å; G60-G62 PolarHBondContact O-N 2.84Å; G62-M65 PolarHBondContact O-N 3.3Å; G62-S66 WeakPolarHBondContact O-CB 3.26Å; G62-S66 PolarHBondContact O-N 3.17Å; G62-E284 WeakPolarHBondContact CA-OE1 3.44Å; G62-E284 PolarHBondContact N-OE1 3.09Å; G62-A288 WeakPolarHBondContact O-CB 3.29Å
63	F	89.8	Confident	86.9	Confident	54 Å²	54	25 Å²	25	24%	0.237	11%	0.106	C	C	.	.	H	α-helix	trans	-68.4	-42.8	174.7	-79.3	-81.1	0	0	0	111.9	T59 G60 M65 S66 I67 I200 I287 A288	T59-F63 HydrophobicContact CG2-CD2 3.66Å; T59-F63 HydrophobicContact CG2-CE2 3.57Å; G60-F63 PolarHBondContact O-N 2.96Å; F63-M65 VanDerWaalsContact C-N 3.32Å; F63-M65 PolarHBondContact O-N 2.88Å; F63-S66 WeakPolarHBondContact CA-OG 3.41Å; F63-S66 PolarHBondContact O-N 2.79Å; F63-S66 VanDerWaalsContact O-N 3.16Å; F63-S66 PolarHBondContact O-OG 3.18Å; F63-I67 PolarHBondContact O-N 3.41Å; F63-I200 HydrophobicContact CB-CD1 4.45Å; F63-I200 HydrophobicContact CD1-CD1 4.08Å; F63-I287 HydrophobicContact CZ-CG2 4.25Å; F63-A288 HydrophobicContact CD1-CB 4.05Å; F63-A288 HydrophobicContact CD2-CB 4.42Å; F63-A288 HydrophobicContact CE1-CB 4.25Å; F63-A288 HydrophobicContact CG-CB 4.15Å
64	L	88.4	Confident	87.4	Confident	4 Å²	4	16 Å²	16	2%	0.021	7%	0.072	C	C	.	.	H	α-helix	trans	-59.2	-44.3	173.7	-91.2	69.8	0	0	0	111.5	Y35 G60 S66 I67 E193 F196 L260	Y35-L64 HydrophobicContact CE1-CD2 4.13Å; G60-L64 VanDerWaalsContact O-CD1 3.31Å; G60-L64 WeakPolarHBondContact O-CD1 3.23Å; G60-L64 PolarHBondContact O-N 2.91Å; L64-S66 VanDerWaalsContact C-N 3.32Å; L64-S66 PolarHBondContact O-N 2.64Å; L64-I67 WeakPolarHBondContact O-CB 3.37Å; L64-I67 PolarHBondContact O-N 3.18Å; L64-E193 HydrophobicContact CD1-CB 4.28Å; L64-E193 HydrophobicContact CD1-CG 3.69Å; L64-F196 HydrophobicContact CD1-CB 4.48Å; L64-F196 HydrophobicContact CD1-CD2 3.54Å; L64-F196 HydrophobicContact CD1-CE2 4.08Å; L64-F196 HydrophobicContact CD1-CG 4.4Å; L64-F196 HydrophobicContact CD2-CD2 4.12Å; L64-F196 HydrophobicContact CD2-CE2 3.79Å; L64-F196 HydrophobicContact CG-CD2 3.51Å; L64-F196 HydrophobicContact CG-CE2 3.54Å; L64-F196 HydrophobicContact CG-CG 4.47Å; L64-L260 HydrophobicContact CB-CD1 3.71Å; L64-L260 HydrophobicContact CD2-CD1 4.29Å; L64-L260 HydrophobicContact CD2-CD2 3.99Å
65	M	91.3	Very high	88.1	Confident	0 Å²	0	15.6 Å²	15.6	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-62.4	-38.2	175.4	174.9	-82.5	-75.4	0	0	112.3	P61 G62 F63 I67 A68 F69 Q104 N253 H257 A285 L289	P61-M65 WeakPolarHBondContact O-CB 3.27Å; P61-M65 PolarHBondContact O-N 3.4Å; G62-M65 PolarHBondContact O-N 3.3Å; F63-M65 VanDerWaalsContact C-N 3.32Å; F63-M65 PolarHBondContact O-N 2.88Å; M65-I67 PolarHBondContact O-N 3.33Å; M65-A68 PolarHBondContact O-N 2.92Å; M65-F69 HydrophobicContact SD-CD2 4.17Å; M65-F69 HydrophobicContact SD-CE2 3.56Å; M65-F69 VanDerWaalsContact SD-CE2 3.56Å; M65-F69 HydrophobicContact SD-CZ 4.43Å; M65-Q104 HydrophobicContact CE-CB 3.78Å; M65-Q104 HydrophobicContact CE-CG 3.76Å; M65-Q104 HydrophobicContact CG-CG 4.33Å; M65-Q104 HydrophobicContact SD-CB 4.33Å; M65-Q104 VanDerWaalsContact SD-CD 3.6Å; M65-Q104 HydrophobicContact SD-CG 3.63Å; M65-N253 WeakPolarHBondContact CG-OD1 3.31Å; M65-N253 PolarHBondContact O-ND2 3.38Å; M65-N253 PolarHBondContact O-OD1 2.96Å; M65-H257 HydrophobicContact CB-CB 4.17Å; M65-H257 HydrophobicContact CG-CB 3.74Å; M65-A285 HydrophobicContact CE-CB 3.97Å; M65-L289 HydrophobicContact CE-CD1 4.01Å; M65-L289 HydrophobicContact CE-CD2 4.26Å; M65-L289 HydrophobicContact CE-CG 4.03Å; M65-L289 HydrophobicContact SD-CD1 4.47Å; M65-L289 HydrophobicContact SD-CD2 3.94Å; M65-L289 HydrophobicContact SD-CG 4.37Å
66	S	91.8	Very high	88.4	Confident	1 Å²	1	14.6 Å²	14.6	1%	0.007	7%	0.065	C	C	.	.	H	α-helix	trans	-68.4	-16.5	-177.1	75.5	0	0	0	0	114.3	G62 F63 L64 A68 F69 S292	G62-S66 WeakPolarHBondContact O-CB 3.26Å; G62-S66 PolarHBondContact O-N 3.17Å; F63-S66 WeakPolarHBondContact CA-OG 3.41Å; F63-S66 PolarHBondContact O-N 2.79Å; F63-S66 VanDerWaalsContact O-N 3.16Å; F63-S66 PolarHBondContact O-OG 3.18Å; L64-S66 VanDerWaalsContact C-N 3.32Å; L64-S66 PolarHBondContact O-N 2.64Å; S66-A68 VanDerWaalsContact C-N 3.31Å; S66-F69 WeakPolarHBondContact O-CB 3.43Å; S66-F69 PolarHBondContact O-N 3.22Å; S66-S292 WeakPolarHBondContact CB-OG 3.44Å; S66-S292 PolarHBondContact O-OG 2.95Å; S66-S292 VanDerWaalsContact O-OG 3.05Å
67	I	89.9	Confident	88.7	Confident	0 Å²	0	5.6 Å²	5.6	0%	0	3%	0.031	C	C	.	.	H	α-helix	trans	-66.3	-36.1	176.8	-70	170.1	0	0	0	111.7	F63 L64 M65 F69 L70 D71 F196 I200 S371	F63-I67 PolarHBondContact O-N 3.41Å; L64-I67 WeakPolarHBondContact O-CB 3.37Å; L64-I67 PolarHBondContact O-N 3.18Å; M65-I67 PolarHBondContact O-N 3.33Å; I67-F69 PolarHBondContact O-N 2.9Å; I67-L70 CarbonylContact O-C 3.6Å; I67-L70 WeakPolarHBondContact O-CA 3.4Å; I67-L70 PolarHBondContact O-N 3.32Å; I67-D71 PolarHBondContact O-N 3.07Å; I67-F196 HydrophobicContact CD1-CB 3.71Å; I67-F196 HydrophobicContact CD1-CD1 3.16Å; I67-F196 HydrophobicContact CD1-CD2 4.19Å; I67-F196 HydrophobicContact CD1-CE1 3.64Å; I67-F196 HydrophobicContact CD1-CG 3.45Å; I67-F196 VanDerWaalsContact CD1-CG 3.45Å; I67-F196 HydrophobicContact CD1-CZ 4.28Å; I67-I200 HydrophobicContact CD1-CD1 4.45Å; I67-I200 HydrophobicContact CG1-CD1 3.88Å; I67-I200 HydrophobicContact CG1-CG1 4.1Å; I67-S371 VanDerWaalsContact CG2-CB 3.42Å; I67-S371 WeakPolarHBondContact CG2-O 3.45Å; I67-S371 WeakPolarHBondContact CG2-OG 3.18Å
68	A	87.8	Confident	89.3	Confident	0 Å²	0	5 Å²	5	0%	0	3%	0.026	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.7	-6.1	173.7	0	0	0	0	0	112.9	M65 S66 M250 N253 T375	M65-A68 PolarHBondContact O-N 2.92Å; S66-A68 VanDerWaalsContact C-N 3.31Å; A68-M250 HydrophobicContact CB-CE 3.29Å; A68-M250 WeakPolarHBondContact O-CE 2.95Å; A68-N253 HydrophobicContact CB-CB 3.92Å; A68-N253 VanDerWaalsContact CB-ND2 3.25Å; A68-N253 WeakPolarHBondContact CB-ND2 3.18Å; A68-T375 HydrophobicContact CB-CG2 4.16Å
69	F	90.6	Very high	89.8	Confident	2 Å²	2	4.8 Å²	4.8	1%	0.009	3%	0.025	C	C	.	.	T	Hydrogen-bonded Turn	trans	-96.5	-1.6	169.6	-69	-112	0	0	0	112.4	M65 S66 I67 N74 Q104 I248 N253 L289 N296	M65-F69 HydrophobicContact SD-CD2 4.17Å; M65-F69 HydrophobicContact SD-CE2 3.56Å; M65-F69 VanDerWaalsContact SD-CE2 3.56Å; M65-F69 HydrophobicContact SD-CZ 4.43Å; S66-F69 WeakPolarHBondContact O-CB 3.43Å; S66-F69 PolarHBondContact O-N 3.22Å; I67-F69 PolarHBondContact O-N 2.9Å; F69-N74 PolarHBondContact O-ND2 3.31Å; F69-Q104 HydrophobicContact CE2-CG 4.46Å; F69-Q104 HydrophobicContact CZ-CG 4.3Å; F69-I248 HydrophobicContact CD1-CB 4.47Å; F69-I248 HydrophobicContact CD1-CG2 3.75Å; F69-I248 HydrophobicContact CE1-CB 4.49Å; F69-I248 HydrophobicContact CE1-CG2 3.45Å; F69-I248 VanDerWaalsContact CE1-CG2 3.45Å; F69-I248 WeakPolarHBondContact CE1-O 3.46Å; F69-I248 WeakPolarHBondContact CZ-O 3.39Å; F69-N253 VanDerWaalsContact CE2-ND2 3.26Å; F69-N253 WeakPolarHBondContact CE2-ND2 3.44Å; F69-L289 HydrophobicContact CB-CD2 4.49Å; F69-L289 HydrophobicContact CD1-CD2 3.82Å; F69-L289 HydrophobicContact CD2-CD2 3.48Å; F69-L289 VanDerWaalsContact CD2-CD2 3.48Å; F69-L289 HydrophobicContact CE1-CD2 3.76Å; F69-L289 HydrophobicContact CE2-CD2 3.45Å; F69-L289 VanDerWaalsContact CE2-CD2 3.45Å; F69-L289 HydrophobicContact CG-CD2 3.68Å; F69-L289 HydrophobicContact CZ-CD1 4.28Å; F69-L289 HydrophobicContact CZ-CD2 3.6Å; F69-N296 PolarHBondContact O-ND2 2.98Å; F69-N296 VanDerWaalsContact O-ND2 3.12Å; F69-N296 PolarHBondContact O-OD1 3.11Å
70	L	92.3	Very high	90	Very high	0 Å²	0	4.4 Å²	4.4	0%	0	2%	0.022	C	C	.	.	S	Bend	trans	-125.4	14.1	-175.1	-62.6	178.1	0	0	0	111.7	I67 I200 M203 I295 N296 A368	I67-L70 CarbonylContact O-C 3.6Å; I67-L70 WeakPolarHBondContact O-CA 3.4Å; I67-L70 PolarHBondContact O-N 3.32Å; L70-I200 HydrophobicContact CD1-CG1 4.39Å; L70-I200 HydrophobicContact CD1-CG2 4.33Å; L70-M203 HydrophobicContact CB-CE 3.92Å; L70-M203 HydrophobicContact CB-SD 4.05Å; L70-M203 HydrophobicContact CD1-CE 3.7Å; L70-M203 HydrophobicContact CG-CE 4.45Å; L70-I295 HydrophobicContact CD1-CD1 3.68Å; L70-I295 HydrophobicContact CD2-CB 3.72Å; L70-I295 HydrophobicContact CD2-CD1 3.95Å; L70-I295 HydrophobicContact CD2-CG1 4.44Å; L70-I295 HydrophobicContact CD2-CG2 3.6Å; L70-I295 HydrophobicContact CG-CD1 4.49Å; L70-N296 VanDerWaalsContact CD2-OD1 3.3Å; L70-N296 WeakPolarHBondContact CD2-OD1 3.25Å; L70-A368 VanDerWaalsContact O-CB 3.23Å; L70-A368 WeakPolarHBondContact O-CB 3.3Å
71	D	91.3	Very high	90.2	Very high	2 Å²	2	4.3 Å²	4.3	1%	0.011	2%	0.02	C	C	.	.	S	Bend	trans	-72.8	161.6	178.7	69.8	-23.8	0	0	0	110.9	I67 G73 N74 I75	I67-D71 PolarHBondContact O-N 3.07Å; D71-G73 PolarHBondContact O-N 2.65Å; D71-G73 VanDerWaalsContact O-N 3.15Å; D71-N74 PolarHBondContact O-N 2.91Å; D71-N74 VanDerWaalsContact O-N 3.11Å; D71-N74 WeakPolarHBondContact OD1-CB 3.22Å; D71-N74 PolarHBondContact OD1-N 3Å; D71-N74 VanDerWaalsContact OD1-N 3.08Å; D71-I75 WeakPolarHBondContact O-CG1 3.2Å; D71-I75 PolarHBondContact O-N 2.89Å
72	P	90.1	Very high	90.3	Very high	0 Å²	0	4.2 Å²	4.2	0%	0	2%	0.02	C	C	.	.	H	α-helix	trans	-56.3	-30.4	178.8	-29.8	39.1	0	0	0	113.9	I75 E76 I342 L365 A368	P72-I75 PolarHBondContact O-N 2.98Å; P72-E76 WeakPolarHBondContact O-CB 3.32Å; P72-E76 PolarHBondContact O-N 3.38Å; P72-I342 HydrophobicContact CB-CD1 4.12Å; P72-L365 HydrophobicContact CB-CD1 4.13Å; P72-L365 HydrophobicContact CG-CD1 4.22Å; P72-A368 HydrophobicContact CG-CB 4.3Å
73	G	88.6	Confident	90.3	Very high	1 Å²	1	4.7 Å²	4.7	1%	0.01	2%	0.024	C	C	.	.	H	α-helix	trans	-60.6	-47.1	175	0	0	0	0	0	112.8	D71 E76 S77 N429	D71-G73 PolarHBondContact O-N 2.65Å; D71-G73 VanDerWaalsContact O-N 3.15Å; G73-E76 PolarHBondContact O-N 2.89Å; G73-S77 PolarHBondContact O-N 3.24Å; G73-S77 VanDerWaalsContact O-N 3.09Å; G73-N429 PolarHBondContact O-ND2 2.96Å
74	N	91	Very high	90.1	Very high	0 Å²	0	4.7 Å²	4.7	0%	0	3%	0.028	C	C	.	.	H	α-helix	trans	-68.3	-43.7	176.4	-163	-28	0	0	0	112.1	F69 D71 E76 S77 D78 A247 N296	F69-N74 PolarHBondContact O-ND2 3.31Å; D71-N74 PolarHBondContact O-N 2.91Å; D71-N74 VanDerWaalsContact O-N 3.11Å; D71-N74 WeakPolarHBondContact OD1-CB 3.22Å; D71-N74 PolarHBondContact OD1-N 3Å; D71-N74 VanDerWaalsContact OD1-N 3.08Å; N74-E76 VanDerWaalsContact C-N 3.28Å; N74-E76 PolarHBondContact O-N 3.26Å; N74-S77 PolarHBondContact O-N 3.37Å; N74-D78 WeakPolarHBondContact O-CB 3.23Å; N74-D78 PolarHBondContact O-N 3.31Å; N74-D78 PolarHBondContact OD1-OD2 3.22Å; N74-D78 VanDerWaalsContact OD1-OD2 3.11Å; N74-A247 HydrophobicContact CB-CB 4.44Å; N74-N296 PolarHBondContact ND2-ND2 3.14Å; N74-N296 PolarHBondContact OD1-ND2 2.8Å
75	I	92.3	Very high	90	Very high	1 Å²	1	4.5 Å²	4.5	1%	0.005	3%	0.027	C	C	.	.	H	α-helix	trans	-57.7	-41.3	175.7	-65.3	169.8	0	0	0	111.1	D71 P72 L79 F207 V299 W361 A368	D71-I75 WeakPolarHBondContact O-CG1 3.2Å; D71-I75 PolarHBondContact O-N 2.89Å; P72-I75 PolarHBondContact O-N 2.98Å; I75-L79 WeakPolarHBondContact O-CB 3.34Å; I75-L79 PolarHBondContact O-N 3.39Å; I75-F207 HydrophobicContact CD1-CE2 3.93Å; I75-F207 HydrophobicContact CD1-CZ 3.85Å; I75-V299 HydrophobicContact CG2-CG1 4.17Å; I75-W361 HydrophobicContact CG2-CH2 3.59Å; I75-W361 HydrophobicContact CG2-CZ2 4.07Å; I75-A368 HydrophobicContact CD1-CB 3.64Å
76	E	90.4	Very high	89.9	Confident	1 Å²	1	4.6 Å²	4.6	1%	0.005	3%	0.028	C	C	.	.	H	α-helix	trans	-65.4	-48.1	176.2	-172.4	149.5	166	0	0	112.2	P72 G73 N74 D78 L79 Q80 I342 N425	P72-E76 WeakPolarHBondContact O-CB 3.32Å; P72-E76 PolarHBondContact O-N 3.38Å; G73-E76 PolarHBondContact O-N 2.89Å; N74-E76 VanDerWaalsContact C-N 3.28Å; N74-E76 PolarHBondContact O-N 3.26Å; E76-D78 VanDerWaalsContact C-N 3.27Å; E76-D78 PolarHBondContact O-N 2.92Å; E76-L79 PolarHBondContact O-N 2.96Å; E76-Q80 HydrophobicContact CG-CG 4.31Å; E76-Q80 WeakPolarHBondContact O-CB 3.4Å; E76-Q80 VanDerWaalsContact O-CG 3.32Å; E76-Q80 WeakPolarHBondContact O-CG 3.41Å; E76-Q80 PolarHBondContact O-N 3.46Å; E76-Q80 PolarHBondContact OE1-NE2 2.76Å; E76-I342 HydrophobicContact CB-CD1 3.86Å; E76-I342 HydrophobicContact CB-CG1 3.8Å; E76-I342 HydrophobicContact CG-CD1 4.5Å; E76-I342 HydrophobicContact CG-CG1 4.14Å; E76-I342 VanDerWaalsContact OE2-CD1 3.23Å; E76-I342 WeakPolarHBondContact OE2-CD1 3.38Å; E76-I342 WeakPolarHBondContact OE2-CG1 3.44Å; E76-N425 VanDerWaalsContact CB-ND2 3.34Å; E76-N425 WeakPolarHBondContact CB-ND2 3.23Å; E76-N425 PolarHBondContact OE2-ND2 2.67Å
77	S	89.7	Confident	89.7	Confident	2 Å²	2	6.3 Å²	6.3	1%	0.014	4%	0.036	C	C	.	.	H	α-helix	trans	-59.2	-40.8	178.7	-172.7	0	0	0	0	111.6	G73 N74 A81 G243 I244	G73-S77 PolarHBondContact O-N 3.24Å; G73-S77 VanDerWaalsContact O-N 3.09Å; N74-S77 PolarHBondContact O-N 3.37Å; S77-A81 VanDerWaalsContact O-CB 3.26Å; S77-A81 WeakPolarHBondContact O-CB 3.48Å; S77-A81 PolarHBondContact O-N 2.92Å; S77-G243 VanDerWaalsContact OG-C 3.31Å; S77-I244 PolarHBondContact OG-N 2.92Å
78	D	92.1	Very high	89.6	Confident	0 Å²	0	8.7 Å²	8.7	0%	0	5%	0.046	C	C	.	.	H	α-helix	trans	-70.8	-40.4	-179.9	-77.5	-16.4	0	0	0	112.2	N74 E76 G82 L93 N296 V299 M300	N74-D78 WeakPolarHBondContact O-CB 3.23Å; N74-D78 PolarHBondContact O-N 3.31Å; N74-D78 PolarHBondContact OD1-OD2 3.22Å; N74-D78 VanDerWaalsContact OD1-OD2 3.11Å; E76-D78 VanDerWaalsContact C-N 3.27Å; E76-D78 PolarHBondContact O-N 2.92Å; D78-G82 PolarHBondContact O-N 3.48Å; D78-L93 VanDerWaalsContact OD1-CD1 3.3Å; D78-L93 WeakPolarHBondContact OD1-CD1 3.48Å; D78-N296 WeakPolarHBondContact OD2-CB 3.32Å; D78-N296 PolarHBondContact OD2-ND2 2.99Å; D78-V299 HydrophobicContact CB-CG1 4.32Å; D78-M300 HydrophobicContact CB-CB 4.38Å; D78-M300 HydrophobicContact CB-CE 4.02Å; D78-M300 WeakPolarHBondContact O-CG 3.12Å; D78-M300 VanDerWaalsContact OD1-CE 3.29Å; D78-M300 WeakPolarHBondContact OD1-CE 3.35Å
79	L	91.6	Very high	89.7	Confident	0 Å²	0	8.9 Å²	8.9	0%	0	5%	0.047	C	C	.	.	H	α-helix	trans	-62	-45.5	174.1	169.2	162.5	0	0	0	111.2	I75 E76 G82 A83 V299 F303 V340 W361	I75-L79 WeakPolarHBondContact O-CB 3.34Å; I75-L79 PolarHBondContact O-N 3.39Å; E76-L79 PolarHBondContact O-N 2.96Å; L79-G82 PolarHBondContact O-N 3.27Å; L79-A83 WeakPolarHBondContact O-CB 3.49Å; L79-A83 PolarHBondContact O-N 3.25Å; L79-V299 HydrophobicContact CB-CG1 4.27Å; L79-F303 HydrophobicContact CB-CD2 3.78Å; L79-F303 HydrophobicContact CB-CE2 4.21Å; L79-F303 HydrophobicContact CB-CG 4.18Å; L79-F303 HydrophobicContact CD1-CD1 4.02Å; L79-F303 HydrophobicContact CD1-CD2 3.78Å; L79-F303 HydrophobicContact CD1-CE1 3.75Å; L79-F303 HydrophobicContact CD1-CE2 3.53Å; L79-F303 HydrophobicContact CD1-CG 4.03Å; L79-F303 HydrophobicContact CD1-CZ 3.49Å; L79-F303 VanDerWaalsContact CD1-CZ 3.49Å; L79-F303 HydrophobicContact CG-CB 4.21Å; L79-F303 HydrophobicContact CG-CD1 3.94Å; L79-F303 HydrophobicContact CG-CD2 3.61Å; L79-F303 HydrophobicContact CG-CE1 4.2Å; L79-F303 HydrophobicContact CG-CE2 3.93Å; L79-F303 HydrophobicContact CG-CG 3.62Å; L79-F303 HydrophobicContact CG-CZ 4.19Å; L79-V340 HydrophobicContact CD2-CB 3.72Å; L79-V340 HydrophobicContact CD2-CG1 3.44Å; L79-V340 VanDerWaalsContact CD2-CG1 3.44Å; L79-V340 HydrophobicContact CG-CG1 4.28Å; L79-W361 HydrophobicContact CD1-CH2 4.14Å; L79-W361 HydrophobicContact CD1-CZ2 3.98Å
80	Q	89.6	Confident	89.8	Confident	20 Å²	20	8.8 Å²	8.8	9%	0.093	5%	0.047	C	C	.	.	H	α-helix	trans	-66.6	-44.3	179.1	-75.1	-176	2.9	0	0	112.1	E76 G82 A83 V84 V340 D426	E76-Q80 HydrophobicContact CG-CG 4.31Å; E76-Q80 WeakPolarHBondContact O-CB 3.4Å; E76-Q80 VanDerWaalsContact O-CG 3.32Å; E76-Q80 WeakPolarHBondContact O-CG 3.41Å; E76-Q80 PolarHBondContact O-N 3.46Å; E76-Q80 PolarHBondContact OE1-NE2 2.76Å; Q80-G82 VanDerWaalsContact C-N 3.29Å; Q80-G82 PolarHBondContact O-N 3.03Å; Q80-A83 PolarHBondContact O-N 3.46Å; Q80-V84 WeakPolarHBondContact O-CB 3.36Å; Q80-V84 WeakPolarHBondContact O-CG2 3.23Å; Q80-V84 PolarHBondContact O-N 2.82Å; Q80-V340 VanDerWaalsContact CG-O 3.3Å; Q80-V340 WeakPolarHBondContact CG-O 2.94Å; Q80-D426 PolarHBondContact NE2-OD1 3.23Å; Q80-D426 PolarHBondContact OE1-OD1 2.67Å
81	A	89.6	Confident	89.8	Confident	0 Å²	0	12.3 Å²	12.3	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-61.2	-40.2	175.3	0	0	0	0	0	111.9	S77 A85 L89 Q240 I244 M300	S77-A81 VanDerWaalsContact O-CB 3.26Å; S77-A81 WeakPolarHBondContact O-CB 3.48Å; S77-A81 PolarHBondContact O-N 2.92Å; A81-A85 WeakPolarHBondContact O-CB 3.46Å; A81-A85 PolarHBondContact O-N 2.73Å; A81-L89 HydrophobicContact CB-CD1 3.98Å; A81-Q240 HydrophobicContact CB-CB 4.23Å; A81-I244 HydrophobicContact CB-CD1 3.57Å; A81-I244 HydrophobicContact CB-CG1 3.95Å; A81-M300 HydrophobicContact CB-CE 3.91Å
82	G	89.9	Confident	89.8	Confident	0 Å²	0	12.8 Å²	12.8	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-60.1	-49.3	171.8	0	0	0	0	0	111.8	D78 L79 Q80 V84 G86 G304	D78-G82 PolarHBondContact O-N 3.48Å; L79-G82 PolarHBondContact O-N 3.27Å; Q80-G82 VanDerWaalsContact C-N 3.29Å; Q80-G82 PolarHBondContact O-N 3.03Å; G82-V84 PolarHBondContact O-N 2.99Å; G82-G86 WeakPolarHBondContact O-CA 3.4Å; G82-G86 PolarHBondContact O-N 3.33Å; G82-G304 VanDerWaalsContact O-CA 3.26Å; G82-G304 WeakPolarHBondContact O-CA 3.46Å
83	A	88.1	Confident	90	Very high	11 Å²	11	12.8 Å²	12.8	9%	0.091	6%	0.063	C	C	.	.	H	α-helix	trans	-62.1	-42.4	-179.2	0	0	0	0	0	113.3	L79 Q80 F307 V340	L79-A83 WeakPolarHBondContact O-CB 3.49Å; L79-A83 PolarHBondContact O-N 3.25Å; Q80-A83 PolarHBondContact O-N 3.46Å; A83-F307 HydrophobicContact CB-CB 3.77Å; A83-F307 HydrophobicContact CB-CG 4.41Å; A83-V340 HydrophobicContact CB-CB 4.14Å; A83-V340 HydrophobicContact CB-CG2 3.56Å
84	V	86.6	Confident	90.2	Very high	53 Å²	53	14.6 Å²	14.6	32%	0.321	7%	0.072	S	C	.	.	H	α-helix	trans	-80.5	-47.4	-176.3	176	0	0	0	0	111.9	Q80 G82 P236 E237 Q240	Q80-V84 WeakPolarHBondContact O-CB 3.36Å; Q80-V84 WeakPolarHBondContact O-CG2 3.23Å; Q80-V84 PolarHBondContact O-N 2.82Å; G82-V84 PolarHBondContact O-N 2.99Å; V84-P236 HydrophobicContact CG1-CB 4.42Å; V84-E237 HydrophobicContact CG1-CG 4.25Å; V84-Q240 HydrophobicContact CB-CG 4.29Å; V84-Q240 HydrophobicContact CG1-CG 4.43Å; V84-Q240 HydrophobicContact CG2-CG 4.35Å
85	A	86.3	Confident	90.3	Very high	1 Å²	1	22.1 Å²	22.1	1%	0.008	10%	0.101	C	C	.	.	H	α-helix	trans	-107.8	-4.2	-169.9	0	0	0	0	0	114.2	A81 F87 K88 L89 E237 Y308	A81-A85 WeakPolarHBondContact O-CB 3.46Å; A81-A85 PolarHBondContact O-N 2.73Å; A85-F87 PolarHBondContact O-N 3.48Å; A85-K88 WeakPolarHBondContact O-CB 3.22Å; A85-K88 WeakPolarHBondContact O-CG 3.45Å; A85-K88 PolarHBondContact O-N 3.44Å; A85-L89 HydrophobicContact CB-CB 4.31Å; A85-L89 HydrophobicContact CB-CD1 3.43Å; A85-L89 VanDerWaalsContact CB-CD1 3.43Å; A85-L89 HydrophobicContact CB-CG 3.48Å; A85-L89 VanDerWaalsContact CB-CG 3.48Å; A85-E237 HydrophobicContact CB-CG 4.08Å; A85-Y308 VanDerWaalsContact C-CE2 3.48Å
86	G	87.4	Confident	90.3	Very high	2 Å²	2	22.2 Å²	22.2	2%	0.021	10%	0.102	C	C	.	.	G	3₁₀ helix	trans	60.8	-129.5	-176.5	0	0	0	0	0	110.4	G82 K88 Y308	G82-G86 WeakPolarHBondContact O-CA 3.4Å; G82-G86 PolarHBondContact O-N 3.33Å; G86-K88 VanDerWaalsContact C-N 3.32Å; G86-K88 PolarHBondContact O-N 3.36Å; G86-Y308 VanDerWaalsContact CA-CD2 3.47Å
87	F	88.8	Confident	90.5	Very high	36 Å²	36	22.7 Å²	22.7	16%	0.158	10%	0.104	C	C	.	.	G	3₁₀ helix	trans	-84.2	0.7	179.1	-53.9	-49.7	0	0	0	114.4	A85 L89 L90 P216 A220 G224 A301 Q305	A85-F87 PolarHBondContact O-N 3.48Å; F87-L89 PolarHBondContact O-N 3.5Å; F87-L90 HydrophobicContact CB-CD1 3.88Å; F87-L90 HydrophobicContact CD1-CD1 4.03Å; F87-L90 HydrophobicContact CG-CD1 4.36Å; F87-P216 HydrophobicContact CE1-CB 4.36Å; F87-P216 HydrophobicContact CZ-CB 4.09Å; F87-A220 HydrophobicContact CD2-CB 3.67Å; F87-A220 HydrophobicContact CE2-CB 4.04Å; F87-G224 VanDerWaalsContact O-CA 3.29Å; F87-G224 WeakPolarHBondContact O-CA 3.44Å; F87-A301 HydrophobicContact CE1-CB 4.26Å; F87-Q305 HydrophobicContact CZ-CB 4.34Å
88	K	87.6	Confident	90.7	Very high	51 Å²	51	26 Å²	26	22%	0.222	12%	0.122	C	C	.	.	G	3₁₀ helix	trans	-74.5	-23.5	-171.6	-60.7	-179.4	-171.4	178.9	0	114.3	A85 G86 W91 P231 Y308	A85-K88 WeakPolarHBondContact O-CB 3.22Å; A85-K88 WeakPolarHBondContact O-CG 3.45Å; A85-K88 PolarHBondContact O-N 3.44Å; G86-K88 VanDerWaalsContact C-N 3.32Å; G86-K88 PolarHBondContact O-N 3.36Å; K88-W91 PolarHBondContact O-NE1 3.33Å; K88-P231 PolarHBondContact NZ-O 2.73Å; K88-Y308 WeakPolarHBondContact CE-OH 3.27Å; K88-Y308 PolarHBondContact NZ-OH 2.7Å
89	L	90.1	Very high	90.7	Very high	4 Å²	4	27 Å²	27	2%	0.021	13%	0.127	C	C	.	.	G	3₁₀ helix	trans	-96.6	2.3	-179.2	-67.1	178.8	0	0	0	113.6	A81 A85 F87 W91 V92 L93 Q240 A241 I244	A81-L89 HydrophobicContact CB-CD1 3.98Å; A85-L89 HydrophobicContact CB-CB 4.31Å; A85-L89 HydrophobicContact CB-CD1 3.43Å; A85-L89 VanDerWaalsContact CB-CD1 3.43Å; A85-L89 HydrophobicContact CB-CG 3.48Å; A85-L89 VanDerWaalsContact CB-CG 3.48Å; F87-L89 PolarHBondContact O-N 3.5Å; L89-W91 VanDerWaalsContact C-N 3.28Å; L89-W91 PolarHBondContact O-N 3.4Å; L89-V92 HydrophobicContact CD2-CG2 3.92Å; L89-V92 WeakPolarHBondContact O-CA 3.45Å; L89-V92 VanDerWaalsContact O-CB 3.3Å; L89-V92 WeakPolarHBondContact O-CB 3.12Å; L89-V92 PolarHBondContact O-N 3.08Å; L89-L93 PolarHBondContact O-N 3.39Å; L89-L93 VanDerWaalsContact O-N 3.08Å; L89-Q240 HydrophobicContact CD1-CB 3.79Å; L89-A241 HydrophobicContact CD2-CB 3.8Å; L89-I244 HydrophobicContact CB-CD1 3.92Å; L89-I244 HydrophobicContact CD1-CD1 4.19Å
90	L	92.2	Very high	90.8	Very high	0 Å²	0	27.1 Å²	27.1	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-60.1	-35	179	-72	177.4	0	0	0	113.2	F87 V92 L93 L94 L221 L225 L297 M300	F87-L90 HydrophobicContact CB-CD1 3.88Å; F87-L90 HydrophobicContact CD1-CD1 4.03Å; F87-L90 HydrophobicContact CG-CD1 4.36Å; L90-V92 VanDerWaalsContact C-N 3.3Å; L90-V92 PolarHBondContact O-N 3.1Å; L90-L93 HydrophobicContact CD2-CD2 4.44Å; L90-L93 WeakPolarHBondContact O-CB 3.34Å; L90-L93 PolarHBondContact O-N 3.32Å; L90-L94 PolarHBondContact O-N 3.26Å; L90-L221 HydrophobicContact CD1-CB 4.49Å; L90-L221 HydrophobicContact CD1-CG 3.92Å; L90-L225 HydrophobicContact CB-CB 4.46Å; L90-L225 HydrophobicContact CB-CD1 4.5Å; L90-L297 HydrophobicContact CD1-CD1 4.29Å; L90-L297 HydrophobicContact CD2-CD1 3.49Å; L90-L297 VanDerWaalsContact CD2-CD1 3.49Å; L90-L297 HydrophobicContact CG-CD1 4.46Å; L90-M300 HydrophobicContact CD2-CB 4.23Å; L90-M300 HydrophobicContact CD2-CG 3.99Å; L90-M300 HydrophobicContact CD2-SD 3.58Å; L90-M300 VanDerWaalsContact CD2-SD 3.58Å; L90-M300 HydrophobicContact CG-SD 4.27Å
91	W	92.1	Very high	91	Very high	73 Å²	73	27.8 Å²	27.8	28%	0.277	13%	0.132	S	C	.	.	H	α-helix	trans	-65.6	-34.4	173.4	71.6	-88.9	0	0	0	111.7	K88 L89 L94 W95 G224 P228	K88-W91 PolarHBondContact O-NE1 3.33Å; L89-W91 VanDerWaalsContact C-N 3.28Å; L89-W91 PolarHBondContact O-N 3.4Å; W91-L94 PolarHBondContact O-N 3.25Å; W91-W95 AromaticContact CE3-CD1 3.84Å; W91-W95 WeakPolarHBondContact O-CB 3.49Å; W91-W95 PolarHBondContact O-N 2.86Å; W91-G224 PolarHBondContact N-O 3.49Å; W91-P228 HydrophobicContact CD2-CB 3.93Å; W91-P228 HydrophobicContact CE3-CB 3.96Å; W91-P228 HydrophobicContact CG-CB 4.3Å; W91-P228 HydrophobicContact CZ3-CB 4.4Å
92	V	92.2	Very high	91.2	Very high	12 Å²	12	30.9 Å²	30.9	7%	0.073	15%	0.148	C	C	.	.	H	α-helix	trans	-65	-45.2	175.6	-177.1	0	0	0	0	109.5	L89 L90 L94 W95 A96 A241 I244 V245	L89-V92 HydrophobicContact CD2-CG2 3.92Å; L89-V92 WeakPolarHBondContact O-CA 3.45Å; L89-V92 VanDerWaalsContact O-CB 3.3Å; L89-V92 WeakPolarHBondContact O-CB 3.12Å; L89-V92 PolarHBondContact O-N 3.08Å; L90-V92 VanDerWaalsContact C-N 3.3Å; L90-V92 PolarHBondContact O-N 3.1Å; V92-L94 PolarHBondContact O-N 3.39Å; V92-W95 PolarHBondContact O-N 3.03Å; V92-A96 WeakPolarHBondContact O-CB 3.42Å; V92-A96 PolarHBondContact O-N 3.05Å; V92-A241 HydrophobicContact CG1-CB 4.26Å; V92-A241 HydrophobicContact CG2-CB 4.28Å; V92-I244 HydrophobicContact CG1-CB 4.43Å; V92-I244 HydrophobicContact CG1-CG2 4.3Å; V92-V245 HydrophobicContact CG1-CG2 4.13Å
93	L	93.3	Very high	91.4	Very high	0 Å²	0	30.9 Å²	30.9	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-53	-52.9	173.6	-177.2	76.8	0	0	0	111	D78 L89 L90 W95 A96 T97 I244 I248 F293 N296 L297 M300	D78-L93 VanDerWaalsContact OD1-CD1 3.3Å; D78-L93 WeakPolarHBondContact OD1-CD1 3.48Å; L89-L93 PolarHBondContact O-N 3.39Å; L89-L93 VanDerWaalsContact O-N 3.08Å; L90-L93 HydrophobicContact CD2-CD2 4.44Å; L90-L93 WeakPolarHBondContact O-CB 3.34Å; L90-L93 PolarHBondContact O-N 3.32Å; L93-W95 PolarHBondContact O-N 3.37Å; L93-A96 PolarHBondContact O-N 2.85Å; L93-T97 PolarHBondContact O-N 3.49Å; L93-T97 PolarHBondContact O-OG1 3.08Å; L93-I244 HydrophobicContact CB-CG2 4.46Å; L93-I244 HydrophobicContact CD1-CG2 4.17Å; L93-I248 HydrophobicContact CD1-CD1 3.6Å; L93-I248 HydrophobicContact CG-CD1 4.46Å; L93-F293 HydrophobicContact CD2-CD2 4.33Å; L93-F293 HydrophobicContact CD2-CE2 3.95Å; L93-F293 HydrophobicContact CG-CD2 4.28Å; L93-F293 HydrophobicContact CG-CE2 4.07Å; L93-N296 HydrophobicContact CD1-CB 4.04Å; L93-N296 HydrophobicContact CD2-CB 4.21Å; L93-L297 HydrophobicContact CD2-CB 4.36Å; L93-M300 HydrophobicContact CB-CE 4.15Å; L93-M300 HydrophobicContact CD1-CE 3.98Å; L93-M300 HydrophobicContact CD2-CE 4.24Å; L93-M300 HydrophobicContact CD2-SD 4.49Å; L93-M300 HydrophobicContact CG-CE 4.36Å
94	L	94.4	Very high	91.7	Very high	39 Å²	39	30.5 Å²	30.5	20%	0.204	14%	0.144	C	C	.	.	H	α-helix	trans	-58.8	-50.4	179.4	178.5	64.6	0	0	0	112.6	L90 W91 V92 A96 T97 L98 L225 F293	L90-L94 PolarHBondContact O-N 3.26Å; W91-L94 PolarHBondContact O-N 3.25Å; V92-L94 PolarHBondContact O-N 3.39Å; L94-A96 VanDerWaalsContact C-N 3.34Å; L94-T97 PolarHBondContact O-N 3.04Å; L94-L98 HydrophobicContact CD1-CD1 4.48Å; L94-L98 HydrophobicContact CG-CD1 4.28Å; L94-L98 WeakPolarHBondContact O-CG 3.31Å; L94-L98 PolarHBondContact O-N 3.22Å; L94-L225 HydrophobicContact CB-CD1 3.72Å; L94-L225 HydrophobicContact CD2-CD1 3.9Å; L94-L225 HydrophobicContact CD2-CG 4.2Å; L94-L225 HydrophobicContact CG-CD1 4.25Å; L94-F293 HydrophobicContact CB-CE2 3.96Å; L94-F293 HydrophobicContact CB-CZ 4.27Å; L94-F293 HydrophobicContact CD1-CD2 4.47Å; L94-F293 HydrophobicContact CD1-CE1 4.19Å; L94-F293 HydrophobicContact CD1-CE2 3.93Å; L94-F293 HydrophobicContact CD1-CZ 3.8Å
95	W	92.6	Very high	92.1	Very high	159 Å²	159	32.8 Å²	32.8	60%	0.602	15%	0.147	S	C	*	.	H	α-helix	trans	-68.3	-34.6	-178.7	-81	104.4	0	0	0	112.5	W91 V92 L93 L98 L99	W91-W95 AromaticContact CE3-CD1 3.84Å; W91-W95 WeakPolarHBondContact O-CB 3.49Å; W91-W95 PolarHBondContact O-N 2.86Å; V92-W95 PolarHBondContact O-N 3.03Å; L93-W95 PolarHBondContact O-N 3.37Å; W95-L98 HydrophobicContact CD2-CD1 4.44Å; W95-L98 HydrophobicContact CE3-CD1 4.05Å; W95-L98 HydrophobicContact CZ3-CD1 4.25Å; W95-L98 PolarHBondContact O-N 3.38Å; W95-L99 VanDerWaalsContact O-CB 3.25Å; W95-L99 WeakPolarHBondContact O-CB 3.38Å; W95-L99 PolarHBondContact O-N 2.81Å
96	A	92.2	Very high	92.4	Very high	3 Å²	3	33 Å²	33	3%	0.025	15%	0.149	C	C	.	.	H	α-helix	trans	-64.3	-44.3	172.6	0	0	0	0	0	110.9	V92 L93 L94 L99 G100 I244 V245 I248	V92-A96 WeakPolarHBondContact O-CB 3.42Å; V92-A96 PolarHBondContact O-N 3.05Å; L93-A96 PolarHBondContact O-N 2.85Å; L94-A96 VanDerWaalsContact C-N 3.34Å; A96-L99 PolarHBondContact O-N 3.28Å; A96-G100 PolarHBondContact O-N 2.65Å; A96-I244 HydrophobicContact CB-CG2 4.24Å; A96-V245 HydrophobicContact CB-CG2 4.17Å; A96-I248 HydrophobicContact CB-CB 4.26Å; A96-I248 HydrophobicContact CB-CD1 3.63Å; A96-I248 HydrophobicContact CB-CG1 4.5Å; A96-I248 HydrophobicContact CB-CG2 4.15Å; A96-I248 WeakPolarHBondContact O-CG2 3.49Å
97	T	94.1	Very high	92.8	Very high	10 Å²	10	33 Å²	33	6%	0.061	15%	0.148	C	C	.	.	H	α-helix	trans	-64.1	-42.1	175.4	-48.7	0	0	0	0	111.4	L93 L94 L99 G100 L101 L289 F293	L93-T97 PolarHBondContact O-N 3.49Å; L93-T97 PolarHBondContact O-OG1 3.08Å; L94-T97 PolarHBondContact O-N 3.04Å; T97-L99 VanDerWaalsContact C-N 3.32Å; T97-L99 PolarHBondContact O-N 3.43Å; T97-G100 CarbonylContact O-C 3.55Å; T97-G100 WeakPolarHBondContact O-CA 3.31Å; T97-G100 PolarHBondContact O-N 3.46Å; T97-L101 PolarHBondContact O-N 3.1Å; T97-L289 HydrophobicContact CG2-CB 4.36Å; T97-F293 HydrophobicContact CG2-CB 3.89Å
98	L	93.8	Very high	93	Very high	73 Å²	73	31.4 Å²	31.4	38%	0.382	14%	0.142	S	C	.	.	H	α-helix	trans	-61.3	-42.2	175.4	-72.7	175.1	0	0	0	111.6	L94 W95 L101 L102	L94-L98 HydrophobicContact CD1-CD1 4.48Å; L94-L98 HydrophobicContact CG-CD1 4.28Å; L94-L98 WeakPolarHBondContact O-CG 3.31Å; L94-L98 PolarHBondContact O-N 3.22Å; W95-L98 HydrophobicContact CD2-CD1 4.44Å; W95-L98 HydrophobicContact CE3-CD1 4.05Å; W95-L98 HydrophobicContact CZ3-CD1 4.25Å; W95-L98 PolarHBondContact O-N 3.38Å; L98-L101 PolarHBondContact O-N 3.47Å; L98-L102 WeakPolarHBondContact O-CG 3.43Å; L98-L102 PolarHBondContact O-N 3.32Å
99	L	92.3	Very high	93.3	Very high	21 Å²	21	30.4 Å²	30.4	11%	0.11	14%	0.136	C	C	.	.	H	α-helix	trans	-64	-41.8	174.4	177.6	55.4	0	0	0	111.5	W95 A96 T97 L101 L102 C103 I249 I469 L472	W95-L99 VanDerWaalsContact O-CB 3.25Å; W95-L99 WeakPolarHBondContact O-CB 3.38Å; W95-L99 PolarHBondContact O-N 2.81Å; A96-L99 PolarHBondContact O-N 3.28Å; T97-L99 VanDerWaalsContact C-N 3.32Å; T97-L99 PolarHBondContact O-N 3.43Å; L99-L101 PolarHBondContact O-N 2.84Å; L99-L102 WeakPolarHBondContact O-CB 3.26Å; L99-L102 PolarHBondContact O-N 3.39Å; L99-C103 PolarHBondContact O-N 3.08Å; L99-C103 PolarHBondContact O-SG 3.39Å; L99-I249 HydrophobicContact CB-CD1 4.18Å; L99-I249 HydrophobicContact CD2-CD1 3.5Å; L99-I249 HydrophobicContact CG-CD1 3.55Å; L99-I469 HydrophobicContact CD1-CB 4.22Å; L99-I469 HydrophobicContact CD1-CD1 3.26Å; L99-I469 HydrophobicContact CD1-CG1 3.32Å; L99-I469 HydrophobicContact CD1-CG2 3.93Å; L99-L472 HydrophobicContact CD2-CD2 4.04Å
100	G	92.8	Very high	93.5	Very high	1 Å²	1	30.2 Å²	30.2	1%	0.01	14%	0.135	C	C	.	.	H	α-helix	trans	-55	-50.2	171	0	0	0	0	0	111.5	A96 T97 L102 C103 Q104	A96-G100 PolarHBondContact O-N 2.65Å; T97-G100 CarbonylContact O-C 3.55Å; T97-G100 WeakPolarHBondContact O-CA 3.31Å; T97-G100 PolarHBondContact O-N 3.46Å; G100-L102 VanDerWaalsContact C-N 3.28Å; G100-L102 PolarHBondContact O-N 3.09Å; G100-C103 PolarHBondContact O-N 3.36Å; G100-Q104 WeakPolarHBondContact O-CB 3.31Å; G100-Q104 WeakPolarHBondContact O-CG 3.32Å; G100-Q104 PolarHBondContact O-N 3.36Å
101	L	95.1	Very high	93.5	Very high	34 Å²	34	30.3 Å²	30.3	18%	0.178	14%	0.136	C	C	.	.	H	α-helix	trans	-58.2	-39.1	176.4	176.8	62.9	0	0	0	112.2	T97 L98 L99 Q104 R105 A285 A286 L289	T97-L101 PolarHBondContact O-N 3.1Å; L98-L101 PolarHBondContact O-N 3.47Å; L99-L101 PolarHBondContact O-N 2.84Å; L101-Q104 PolarHBondContact O-N 3.1Å; L101-R105 VanDerWaalsContact O-CB 3.26Å; L101-R105 WeakPolarHBondContact O-CB 3.08Å; L101-R105 PolarHBondContact O-N 3.39Å; L101-A285 HydrophobicContact CD1-CB 4.11Å; L101-A286 HydrophobicContact CD1-CB 4.24Å; L101-A286 HydrophobicContact CD2-CB 4.14Å; L101-L289 HydrophobicContact CB-CD1 3.7Å; L101-L289 HydrophobicContact CD1-CD1 3.84Å; L101-L289 HydrophobicContact CG-CD1 4.36Å
102	L	93.7	Very high	93.5	Very high	65 Å²	65	26.9 Å²	26.9	34%	0.34	12%	0.123	S	C	.	.	H	α-helix	trans	-64.2	-48.2	175.5	-68.6	172.9	0	0	0	111.6	L98 L99 G100 Q104 R105 L106 V465	L98-L102 WeakPolarHBondContact O-CG 3.43Å; L98-L102 PolarHBondContact O-N 3.32Å; L99-L102 WeakPolarHBondContact O-CB 3.26Å; L99-L102 PolarHBondContact O-N 3.39Å; G100-L102 VanDerWaalsContact C-N 3.28Å; G100-L102 PolarHBondContact O-N 3.09Å; L102-Q104 VanDerWaalsContact C-N 3.32Å; L102-Q104 PolarHBondContact O-N 3.37Å; L102-R105 PolarHBondContact O-N 3.41Å; L102-L106 WeakPolarHBondContact O-CG 3.36Å; L102-L106 PolarHBondContact O-N 2.69Å; L102-L106 VanDerWaalsContact O-N 3.1Å; L102-V465 HydrophobicContact CD1-CG1 4Å
103	C	93.3	Very high	93.5	Very high	1 Å²	1	27.2 Å²	27.2	1%	0.007	13%	0.125	C	C	.	.	H	α-helix	trans	-60.5	-42.9	175.9	-70.1	0	0	0	0	111.5	L99 G100 L106 A107 I254	L99-C103 PolarHBondContact O-N 3.08Å; L99-C103 PolarHBondContact O-SG 3.39Å; G100-C103 PolarHBondContact O-N 3.36Å; C103-L106 WeakPolarHBondContact O-CB 3.28Å; C103-L106 PolarHBondContact O-N 3.07Å; C103-L106 VanDerWaalsContact O-N 3.16Å; C103-A107 PolarHBondContact O-N 3.2Å; C103-I254 HydrophobicContact CB-CD1 4.32Å
104	Q	94.9	Very high	93.3	Very high	3 Å²	3	28.7 Å²	28.7	1%	0.014	13%	0.134	C	C	.	.	H	α-helix	trans	-68	-36.8	179.6	-68.8	-61	-10.1	0	0	112.6	M65 F69 G100 L101 L102 L106 A107 A108 N253 H257 L289	M65-Q104 HydrophobicContact CE-CB 3.78Å; M65-Q104 HydrophobicContact CE-CG 3.76Å; M65-Q104 HydrophobicContact CG-CG 4.33Å; M65-Q104 HydrophobicContact SD-CB 4.33Å; M65-Q104 VanDerWaalsContact SD-CD 3.6Å; M65-Q104 HydrophobicContact SD-CG 3.63Å; F69-Q104 HydrophobicContact CE2-CG 4.46Å; F69-Q104 HydrophobicContact CZ-CG 4.3Å; G100-Q104 WeakPolarHBondContact O-CB 3.31Å; G100-Q104 WeakPolarHBondContact O-CG 3.32Å; G100-Q104 PolarHBondContact O-N 3.36Å; L101-Q104 PolarHBondContact O-N 3.1Å; L102-Q104 VanDerWaalsContact C-N 3.32Å; L102-Q104 PolarHBondContact O-N 3.37Å; Q104-L106 VanDerWaalsContact C-N 3.29Å; Q104-L106 PolarHBondContact O-N 3.29Å; Q104-A107 PolarHBondContact O-N 2.87Å; Q104-A108 WeakPolarHBondContact O-CB 3.47Å; Q104-A108 PolarHBondContact O-N 3Å; Q104-N253 PolarHBondContact NE2-ND2 3.31Å; Q104-H257 PolarHBondContact O-ND1 3.5Å; Q104-H257 PolarHBondContact OE1-ND1 3.19Å; Q104-L289 HydrophobicContact CG-CD1 4.48Å
105	R	94.6	Very high	92.9	Very high	100 Å²	100	27.3 Å²	27.3	38%	0.377	13%	0.13	S	C	.	.	H	α-helix	trans	-60.3	-41.1	170.5	176.6	-172.6	177.9	-152.5	-1.1	111.3	L101 L102 R109 L282	L101-R105 VanDerWaalsContact O-CB 3.26Å; L101-R105 WeakPolarHBondContact O-CB 3.08Å; L101-R105 PolarHBondContact O-N 3.39Å; L102-R105 PolarHBondContact O-N 3.41Å; R105-R109 WeakPolarHBondContact O-CB 3.29Å; R105-R109 VanDerWaalsContact O-CG 3.23Å; R105-R109 WeakPolarHBondContact O-CG 3.35Å; R105-R109 PolarHBondContact O-N 3.5Å; R105-L282 HydrophobicContact CB-CD1 4.15Å; R105-L282 HydrophobicContact CG-CD1 3.91Å
106	L	93.9	Very high	92.8	Very high	7 Å²	7	23 Å²	23	4%	0.037	12%	0.115	C	C	.	.	H	α-helix	trans	-66.9	-42.7	177.7	-67.3	175.2	0	0	0	111.3	L102 C103 Q104 R109 L110 I443 L444 T447 T466	L102-L106 WeakPolarHBondContact O-CG 3.36Å; L102-L106 PolarHBondContact O-N 2.69Å; L102-L106 VanDerWaalsContact O-N 3.1Å; C103-L106 WeakPolarHBondContact O-CB 3.28Å; C103-L106 PolarHBondContact O-N 3.07Å; C103-L106 VanDerWaalsContact O-N 3.16Å; Q104-L106 VanDerWaalsContact C-N 3.29Å; Q104-L106 PolarHBondContact O-N 3.29Å; L106-R109 PolarHBondContact O-N 2.93Å; L106-L110 PolarHBondContact O-N 3.33Å; L106-I443 HydrophobicContact CB-CG1 3.9Å; L106-L444 HydrophobicContact CD1-CD2 3.72Å; L106-T447 HydrophobicContact CB-CG2 3.99Å; L106-T447 HydrophobicContact CD2-CG2 4.29Å; L106-T466 HydrophobicContact CD1-CG2 3.76Å
107	A	94.6	Very high	92.8	Very high	0 Å²	0	23.1 Å²	23.1	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-57.8	-50.1	174.2	0	0	0	0	0	112.5	C103 Q104 R109 L110 G111 I254 H257 S258 I443	C103-A107 PolarHBondContact O-N 3.2Å; Q104-A107 PolarHBondContact O-N 2.87Å; A107-R109 PolarHBondContact O-N 2.89Å; A107-L110 PolarHBondContact O-N 3.45Å; A107-G111 PolarHBondContact O-N 2.96Å; A107-G111 VanDerWaalsContact O-N 3.16Å; A107-I254 HydrophobicContact CB-CG2 3.97Å; A107-I254 WeakPolarHBondContact CB-O 3.4Å; A107-H257 HydrophobicContact CB-CB 4.5Å; A107-S258 WeakPolarHBondContact O-CB 3.37Å; A107-I443 HydrophobicContact CB-CD1 4.49Å
108	A	93.9	Very high	92.7	Very high	4 Å²	4	22.7 Å²	22.7	3%	0.033	11%	0.113	C	C	.	.	H	α-helix	trans	-60.3	-45.3	176.7	0	0	0	0	0	111.8	Q104 L110 G111 V112 V261	Q104-A108 WeakPolarHBondContact O-CB 3.47Å; Q104-A108 PolarHBondContact O-N 3Å; A108-L110 VanDerWaalsContact C-N 3.32Å; A108-L110 PolarHBondContact O-N 2.99Å; A108-G111 PolarHBondContact O-N 3.41Å; A108-V112 WeakPolarHBondContact O-CB 3.43Å; A108-V112 VanDerWaalsContact O-CG2 3.23Å; A108-V112 WeakPolarHBondContact O-CG2 3.42Å; A108-V112 PolarHBondContact O-N 3.29Å; A108-V261 HydrophobicContact CB-CG1 3.93Å
109	R	94.1	Very high	92.6	Very high	30 Å²	30	19.2 Å²	19.2	11%	0.113	9%	0.094	C	C	.	.	H	α-helix	trans	-60.3	-41.2	177.8	-76.7	175.6	73.1	-154.9	2.4	112.2	R105 L106 A107 V112 V113 M453 F456 N458	R105-R109 WeakPolarHBondContact O-CB 3.29Å; R105-R109 VanDerWaalsContact O-CG 3.23Å; R105-R109 WeakPolarHBondContact O-CG 3.35Å; R105-R109 PolarHBondContact O-N 3.5Å; L106-R109 PolarHBondContact O-N 2.93Å; A107-R109 PolarHBondContact O-N 2.89Å; R109-V112 PolarHBondContact O-N 3.19Å; R109-V113 WeakPolarHBondContact O-CB 3.28Å; R109-V113 VanDerWaalsContact O-CG2 3.23Å; R109-V113 WeakPolarHBondContact O-CG2 3.43Å; R109-V113 PolarHBondContact O-N 3.34Å; R109-M453 HydrophobicContact CB-CE 4.41Å; R109-F456 PolarHBondContact NH2-O 2.91Å; R109-N458 PolarHBondContact NH1-OD1 3.34Å
110	L	93.6	Very high	92.6	Very high	0 Å²	0	21.1 Å²	21.1	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-60.4	-49.6	177.7	-175.9	72.8	0	0	0	110.7	L106 A107 A108 V112 T114 L118 V121 I443 F446 T447 L452 M453	L106-L110 PolarHBondContact O-N 3.33Å; A107-L110 PolarHBondContact O-N 3.45Å; A108-L110 VanDerWaalsContact C-N 3.32Å; A108-L110 PolarHBondContact O-N 2.99Å; L110-V112 PolarHBondContact O-N 3.38Å; L110-T114 HydrophobicContact CD1-CG2 3.84Å; L110-T114 HydrophobicContact CG-CG2 4.48Å; L110-T114 WeakPolarHBondContact O-CB 3.38Å; L110-T114 WeakPolarHBondContact O-CG2 3.38Å; L110-T114 PolarHBondContact O-N 3.34Å; L110-T114 PolarHBondContact O-OG1 3.48Å; L110-L118 HydrophobicContact CD2-CB 4.05Å; L110-L118 HydrophobicContact CD2-CD1 3.51Å; L110-L118 HydrophobicContact CD2-CG 4.38Å; L110-V121 HydrophobicContact CD2-CG2 4.45Å; L110-I443 HydrophobicContact CB-CD1 3.82Å; L110-I443 HydrophobicContact CD2-CD1 3.63Å; L110-I443 HydrophobicContact CG-CD1 4.3Å; L110-F446 HydrophobicContact CD1-CB 4.01Å; L110-T447 HydrophobicContact CB-CG2 4.29Å; L110-L452 HydrophobicContact CD1-CD2 3.76Å; L110-M453 HydrophobicContact CB-CE 3.93Å; L110-M453 HydrophobicContact CD1-CE 3.78Å; L110-M453 HydrophobicContact CD1-SD 4.43Å; L110-M453 HydrophobicContact CG-CE 4.49Å
111	G	91.9	Very high	92.5	Very high	1 Å²	1	21.1 Å²	21.1	1%	0.01	10%	0.103	C	C	.	.	H	α-helix	trans	-63.1	-40	179.1	0	0	0	0	0	113.5	A107 A108 G115 K116	A107-G111 PolarHBondContact O-N 2.96Å; A107-G111 VanDerWaalsContact O-N 3.16Å; A108-G111 PolarHBondContact O-N 3.41Å; G111-G115 VanDerWaalsContact O-CA 3.22Å; G111-G115 WeakPolarHBondContact O-CA 3.32Å; G111-G115 PolarHBondContact O-N 3.16Å; G111-K116 WeakPolarHBondContact CA-O 3.44Å
112	V	92	Very high	92.3	Very high	2 Å²	2	19.5 Å²	19.5	1%	0.012	9%	0.094	C	C	.	.	H	α-helix	trans	-68.5	-47.7	179.5	171.3	0	0	0	0	111.7	A108 R109 L110 V261 I266 I274 A277 F281	A108-V112 WeakPolarHBondContact O-CB 3.43Å; A108-V112 VanDerWaalsContact O-CG2 3.23Å; A108-V112 WeakPolarHBondContact O-CG2 3.42Å; A108-V112 PolarHBondContact O-N 3.29Å; R109-V112 PolarHBondContact O-N 3.19Å; L110-V112 PolarHBondContact O-N 3.38Å; V112-V261 HydrophobicContact CG2-CB 4.12Å; V112-V261 HydrophobicContact CG2-CG2 4.17Å; V112-I266 HydrophobicContact CG1-CD1 4.14Å; V112-I266 HydrophobicContact CG2-CD1 4.26Å; V112-I274 HydrophobicContact CG1-CG2 4.19Å; V112-A277 HydrophobicContact CG1-CB 3.99Å; V112-F281 HydrophobicContact CG2-CD2 3.54Å; V112-F281 HydrophobicContact CG2-CE2 3.56Å
113	V	91.8	Very high	92.1	Very high	18 Å²	18	17.7 Å²	17.7	11%	0.109	8%	0.084	C	C	.	.	H	α-helix	trans	-73.5	-49.4	-174.9	174.6	0	0	0	0	111.4	R109 I274 M453 F456	R109-V113 WeakPolarHBondContact O-CB 3.28Å; R109-V113 VanDerWaalsContact O-CG2 3.23Å; R109-V113 WeakPolarHBondContact O-CG2 3.43Å; R109-V113 PolarHBondContact O-N 3.34Å; V113-I274 HydrophobicContact CG2-CG2 3.89Å; V113-M453 HydrophobicContact CB-SD 3.92Å; V113-M453 HydrophobicContact CG1-SD 3.95Å; V113-M453 HydrophobicContact CG2-SD 4.18Å; V113-F456 HydrophobicContact CG1-CD2 4.34Å; V113-F456 HydrophobicContact CG2-CB 3.92Å; V113-F456 HydrophobicContact CG2-CD2 4.19Å; V113-F456 HydrophobicContact CG2-CG 4.09Å
114	T	88.9	Confident	91.9	Very high	31 Å²	31	19.8 Å²	19.8	19%	0.19	10%	0.095	C	C	.	.	H	α-helix	trans	-83.4	-24.4	-174.1	68.2	0	0	0	0	112.5	L110 K116 L452	L110-T114 HydrophobicContact CD1-CG2 3.84Å; L110-T114 HydrophobicContact CG-CG2 4.48Å; L110-T114 WeakPolarHBondContact O-CB 3.38Å; L110-T114 WeakPolarHBondContact O-CG2 3.38Å; L110-T114 PolarHBondContact O-N 3.34Å; L110-T114 PolarHBondContact O-OG1 3.48Å; T114-K116 PolarHBondContact O-N 3Å; T114-K116 PolarHBondContact OG1-N 2.95Å; T114-K116 VanDerWaalsContact OG1-N 3.11Å; T114-K116 PolarHBondContact OG1-O 3Å; T114-K116 VanDerWaalsContact OG1-O 3.07Å; T114-L452 HydrophobicContact CG2-CD1 3.68Å; T114-L452 HydrophobicContact CG2-CD2 4.14Å; T114-L452 HydrophobicContact CG2-CG 3.65Å
115	G	87.8	Confident	91.4	Very high	11 Å²	11	20.5 Å²	20.5	11%	0.113	10%	0.097	C	C	.	.	S	Bend	trans	69.9	4.2	-170	0	0	0	0	0	115.1	G111 K262 R268	G111-G115 VanDerWaalsContact O-CA 3.22Å; G111-G115 WeakPolarHBondContact O-CA 3.32Å; G111-G115 PolarHBondContact O-N 3.16Å; G115-K262 WeakPolarHBondContact O-CE 3.31Å; G115-R268 VanDerWaalsContact CA-NE 3.26Å
116	K	90.1	Very high	91.1	Very high	68 Å²	68	16 Å²	16	30%	0.296	8%	0.081	S	C	.	.	S	Bend	trans	-112.5	147	177	-63.1	-169.8	-179	-167	0	109.3	G111 T114 E120 V121 L124	G111-K116 WeakPolarHBondContact CA-O 3.44Å; T114-K116 PolarHBondContact O-N 3Å; T114-K116 PolarHBondContact OG1-N 2.95Å; T114-K116 VanDerWaalsContact OG1-N 3.11Å; T114-K116 PolarHBondContact OG1-O 3Å; T114-K116 VanDerWaalsContact OG1-O 3.07Å; K116-E120 WeakPolarHBondContact CA-OE2 3.49Å; K116-E120 HydrophobicContact CB-CB 4.05Å; K116-E120 VanDerWaalsContact CB-OE2 3.28Å; K116-E120 WeakPolarHBondContact CB-OE2 3.05Å; K116-V121 HydrophobicContact CB-CG2 3.93Å; K116-L124 HydrophobicContact CD-CD1 3.64Å; K116-L124 VanDerWaalsContact NZ-CD1 3.27Å
117	D	92.1	Very high	90.8	Very high	6 Å²	6	18.5 Å²	18.5	3%	0.032	10%	0.097	C	C	.	.			trans	-78	166.5	172.7	59.3	72.2	0	0	0	110.9	G119 E120 V121 A259 K262	D117-G119 PolarHBondContact O-N 3.33Å; D117-G119 WeakPolarHBondContact OD1-CA 3.3Å; D117-G119 PolarHBondContact OD1-N 3.16Å; D117-E120 PolarHBondContact N-OE2 3.07Å; D117-E120 PolarHBondContact O-N 3.01Å; D117-E120 WeakPolarHBondContact OD1-CG 3.49Å; D117-E120 PolarHBondContact OD1-N 3.47Å; D117-E120 WeakPolarHBondContact OD2-CG 3.4Å; D117-E120 VanDerWaalsContact OD2-OE2 3.12Å; D117-V121 WeakPolarHBondContact O-CG2 3.28Å; D117-V121 PolarHBondContact O-N 2.95Å; D117-A259 HydrophobicContact CB-CB 3.85Å; D117-K262 HydrophobicContact CB-CD 4.14Å; D117-K262 IonicContact OD2-NZ 2.64Å; D117-K262 PolarHBondContact OD2-NZ 3.06Å
118	L	92.6	Very high	90.4	Very high	0 Å²	0	26 Å²	26	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-59.6	-34.4	-178.2	-178.8	62.1	0	0	0	112.1	L110 V121 C122 I254 Y255 S258 P442 I443 F446	L110-L118 HydrophobicContact CD2-CB 4.05Å; L110-L118 HydrophobicContact CD2-CD1 3.51Å; L110-L118 HydrophobicContact CD2-CG 4.38Å; L118-V121 PolarHBondContact O-N 3.2Å; L118-C122 WeakPolarHBondContact O-CB 3.31Å; L118-C122 PolarHBondContact O-N 3.29Å; L118-C122 PolarHBondContact O-SG 3.26Å; L118-I254 HydrophobicContact CD2-CG2 3.85Å; L118-Y255 HydrophobicContact CB-CD1 3.74Å; L118-Y255 HydrophobicContact CB-CE1 3.97Å; L118-Y255 HydrophobicContact CD2-CD1 3.77Å; L118-Y255 HydrophobicContact CD2-CD2 4.33Å; L118-Y255 HydrophobicContact CD2-CE1 3.55Å; L118-Y255 HydrophobicContact CD2-CE2 4.14Å; L118-Y255 HydrophobicContact CD2-CG 4.15Å; L118-Y255 HydrophobicContact CG-CD1 3.77Å; L118-Y255 HydrophobicContact CG-CE1 3.48Å; L118-Y255 VanDerWaalsContact CG-CE1 3.48Å; L118-S258 WeakPolarHBondContact CB-OG 3.47Å; L118-S258 PolarHBondContact N-OG 3.48Å; L118-P442 HydrophobicContact CD1-CB 4.2Å; L118-I443 HydrophobicContact CD1-CB 4.4Å; L118-I443 HydrophobicContact CD1-CD1 4.18Å; L118-I443 HydrophobicContact CD2-CB 4.13Å; L118-F446 HydrophobicContact CD1-CD2 3.85Å; L118-F446 HydrophobicContact CD1-CE2 4.43Å
119	G	91.4	Very high	90.2	Very high	0 Å²	0	30.6 Å²	30.6	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-66.6	-45	177.9	0	0	0	0	0	112.1	D117 V121 C122 H123 G386	D117-G119 PolarHBondContact O-N 3.33Å; D117-G119 WeakPolarHBondContact OD1-CA 3.3Å; D117-G119 PolarHBondContact OD1-N 3.16Å; G119-V121 VanDerWaalsContact C-N 3.35Å; G119-V121 PolarHBondContact O-N 2.69Å; G119-C122 WeakPolarHBondContact O-CB 3.03Å; G119-C122 PolarHBondContact O-N 2.72Å; G119-H123 PolarHBondContact O-N 2.96Å; G119-G386 CarbonylContact O-C 3.51Å
120	E	91.4	Very high	89.9	Confident	61 Å²	61	30.2 Å²	30.2	29%	0.285	16%	0.158	S	C	.	.	H	α-helix	trans	-60.5	-42	174.1	-71.7	171.2	156.8	0	0	111.8	K116 D117 H123 L124 K262	K116-E120 WeakPolarHBondContact CA-OE2 3.49Å; K116-E120 HydrophobicContact CB-CB 4.05Å; K116-E120 VanDerWaalsContact CB-OE2 3.28Å; K116-E120 WeakPolarHBondContact CB-OE2 3.05Å; D117-E120 PolarHBondContact N-OE2 3.07Å; D117-E120 PolarHBondContact O-N 3.01Å; D117-E120 WeakPolarHBondContact OD1-CG 3.49Å; D117-E120 PolarHBondContact OD1-N 3.47Å; D117-E120 WeakPolarHBondContact OD2-CG 3.4Å; D117-E120 VanDerWaalsContact OD2-OE2 3.12Å; E120-H123 WeakPolarHBondContact O-CB 3.27Å; E120-H123 PolarHBondContact O-N 2.98Å; E120-L124 VanDerWaalsContact O-CG 3.28Å; E120-L124 WeakPolarHBondContact O-CG 3.19Å; E120-L124 PolarHBondContact O-N 3.21Å; E120-K262 IonicContact OE1-NZ 3.4Å; E120-K262 PolarHBondContact OE1-NZ 3.46Å; E120-K262 IonicContact OE2-NZ 3.54Å; E120-K262 PolarHBondContact OE2-NZ 3.25Å
121	V	91.4	Very high	89.8	Confident	1 Å²	1	32.1 Å²	32.1	1%	0.006	17%	0.166	C	C	.	.	H	α-helix	trans	-66.5	-44	176.7	177.2	0	0	0	0	110.9	L110 K116 D117 L118 G119 H123 L124 Y125 F446 L452	L110-V121 HydrophobicContact CD2-CG2 4.45Å; K116-V121 HydrophobicContact CB-CG2 3.93Å; D117-V121 WeakPolarHBondContact O-CG2 3.28Å; D117-V121 PolarHBondContact O-N 2.95Å; L118-V121 PolarHBondContact O-N 3.2Å; G119-V121 VanDerWaalsContact C-N 3.35Å; G119-V121 PolarHBondContact O-N 2.69Å; V121-H123 PolarHBondContact O-N 3.11Å; V121-L124 PolarHBondContact O-N 2.95Å; V121-L124 VanDerWaalsContact O-N 3.15Å; V121-Y125 HydrophobicContact CG1-CD2 3.94Å; V121-Y125 HydrophobicContact CG1-CE2 4.27Å; V121-Y125 PolarHBondContact O-N 3.2Å; V121-Y125 VanDerWaalsContact O-N 3.12Å; V121-F446 HydrophobicContact CG1-CB 4.27Å; V121-F446 HydrophobicContact CG1-CD1 3.62Å; V121-F446 HydrophobicContact CG1-CD2 3.7Å; V121-F446 HydrophobicContact CG1-CE1 3.84Å; V121-F446 HydrophobicContact CG1-CE2 3.9Å; V121-F446 HydrophobicContact CG1-CG 3.58Å; V121-F446 HydrophobicContact CG1-CZ 3.97Å; V121-L452 HydrophobicContact CG1-CD2 3.72Å
122	C	90.9	Very high	89.7	Confident	0 Å²	0	34.9 Å²	34.9	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-56.4	-39.8	172.7	-76.6	0	0	0	0	111.6	L118 G119 L124 Y126 L134 F387	L118-C122 WeakPolarHBondContact O-CB 3.31Å; L118-C122 PolarHBondContact O-N 3.29Å; L118-C122 PolarHBondContact O-SG 3.26Å; G119-C122 WeakPolarHBondContact O-CB 3.03Å; G119-C122 PolarHBondContact O-N 2.72Å; C122-L124 VanDerWaalsContact C-N 3.31Å; C122-L124 PolarHBondContact O-N 2.97Å; C122-Y126 HydrophobicContact CB-CD2 3.95Å; C122-Y126 HydrophobicContact CB-CE2 4.4Å; C122-Y126 WeakPolarHBondContact O-CB 3.39Å; C122-Y126 PolarHBondContact O-N 2.87Å; C122-L134 HydrophobicContact CB-CD2 4.46Å; C122-F387 HydrophobicContact CB-CD1 4.25Å; C122-F387 HydrophobicContact CB-CE1 3.52Å; C122-F387 HydrophobicContact CB-CZ 3.73Å
123	H	89.3	Confident	89.7	Confident	27 Å²	27	38.6 Å²	38.6	13%	0.125	20%	0.202	C	C	.	.	H	α-helix	trans	-63.1	-37.8	178.3	-178	104	0	0	0	113.5	G119 E120 V121 R131 G386 F387 R389	G119-H123 PolarHBondContact O-N 2.96Å; E120-H123 WeakPolarHBondContact O-CB 3.27Å; E120-H123 PolarHBondContact O-N 2.98Å; V121-H123 PolarHBondContact O-N 3.11Å; H123-R131 PolarHBondContact CE1-NH1 3.15Å; H123-R131 PolarHBondContact ND1-NH1 3.29Å; H123-R131 PolarHBondContact NE2-NH1 2.97Å; H123-R131 PolarHBondContact O-NH1 3.27Å; H123-G386 VanDerWaalsContact CB-O 3.26Å; H123-G386 WeakPolarHBondContact CB-O 3.45Å; H123-F387 PolarHBondContact ND1-O 3.44Å; H123-R389 VanDerWaalsContact CD2-CZ 3.49Å; H123-R389 PolarHBondContact CD2-NE 2.65Å; H123-R389 VanDerWaalsContact CD2-NE 3.3Å; H123-R389 PolarHBondContact CD2-NH2 2.88Å; H123-R389 PolarHBondContact NE2-NE 3.1Å
124	L	87.9	Confident	89.7	Confident	45 Å²	45	37.8 Å²	37.8	24%	0.236	20%	0.197	C	C	.	.	H	α-helix	trans	-77	-36.1	-175.8	-68.9	166	0	0	0	112.9	K116 E120 V121 C122 L536	K116-L124 HydrophobicContact CD-CD1 3.64Å; K116-L124 VanDerWaalsContact NZ-CD1 3.27Å; E120-L124 VanDerWaalsContact O-CG 3.28Å; E120-L124 WeakPolarHBondContact O-CG 3.19Å; E120-L124 PolarHBondContact O-N 3.21Å; V121-L124 PolarHBondContact O-N 2.95Å; V121-L124 VanDerWaalsContact O-N 3.15Å; C122-L124 VanDerWaalsContact C-N 3.31Å; C122-L124 PolarHBondContact O-N 2.97Å; L124-L536 HydrophobicContact CB-CD1 4.01Å
125	Y	86.2	Confident	89.9	Confident	18 Å²	18	39 Å²	39	7%	0.071	20%	0.198	C	C	.	.	H	α-helix	trans	-100.1	-31.1	-173.9	-77.9	-90.9	0	0	0	114.1	V121 F446 M449 L452 F532 L536	V121-Y125 HydrophobicContact CG1-CD2 3.94Å; V121-Y125 HydrophobicContact CG1-CE2 4.27Å; V121-Y125 PolarHBondContact O-N 3.2Å; V121-Y125 VanDerWaalsContact O-N 3.12Å; Y125-F446 HydrophobicContact CD1-CE1 4.35Å; Y125-F446 HydrophobicContact CD2-CD1 4.44Å; Y125-F446 AromaticContact CD2-CE1 3.86Å; Y125-F446 HydrophobicContact CD2-CE1 3.86Å; Y125-F446 AromaticContact CG-CE1 3.67Å; Y125-F446 HydrophobicContact CG-CE1 3.67Å; Y125-F446 HydrophobicContact CG-CZ 4.36Å; Y125-M449 HydrophobicContact CD1-CE 3.9Å; Y125-M449 HydrophobicContact CE1-CE 3.5Å; Y125-L452 HydrophobicContact CE2-CD1 4.07Å; Y125-F532 HydrophobicContact CD1-CD1 4.34Å; Y125-F532 HydrophobicContact CD1-CE1 4.28Å; Y125-L536 HydrophobicContact CE1-CG 4.3Å; Y125-L536 HydrophobicContact CE2-CD1 4.29Å
126	Y	87.3	Confident	90.1	Very high	6 Å²	6	43.4 Å²	43.4	2%	0.024	22%	0.218	C	C	.	.	S	Bend	trans	-88.2	139.6	-179.6	-69.3	-56.7	0	0	0	112.3	C122 L134 P442 F446 Y510 L511 T514 F532	C122-Y126 HydrophobicContact CB-CD2 3.95Å; C122-Y126 HydrophobicContact CB-CE2 4.4Å; C122-Y126 WeakPolarHBondContact O-CB 3.39Å; C122-Y126 PolarHBondContact O-N 2.87Å; Y126-L134 HydrophobicContact CD2-CD2 4.23Å; Y126-L134 HydrophobicContact CE2-CD2 4.17Å; Y126-P442 HydrophobicContact CE2-CB 4.3Å; Y126-P442 HydrophobicContact CE2-CG 4.33Å; Y126-F446 HydrophobicContact CD2-CZ 4.2Å; Y126-F446 AromaticContact CE2-CE2 3.81Å; Y126-F446 HydrophobicContact CE2-CE2 3.81Å; Y126-F446 AromaticContact CE2-CZ 3.71Å; Y126-F446 HydrophobicContact CE2-CZ 3.71Å; Y126-Y510 AromaticContact CD1-CE1 3.78Å; Y126-Y510 HydrophobicContact CD1-CE1 3.78Å; Y126-Y510 AromaticContact CE1-CE1 3.89Å; Y126-Y510 HydrophobicContact CE1-CE1 3.89Å; Y126-L511 HydrophobicContact CE1-CD2 3.9Å; Y126-L511 HydrophobicContact CE2-CD2 4.16Å; Y126-L511 WeakPolarHBondContact OH-CD2 3.11Å; Y126-T514 HydrophobicContact CE1-CG2 4.18Å; Y126-T514 PolarHBondContact OH-OG1 3.39Å; Y126-F532 AromaticContact CD1-CZ 3.96Å; Y126-F532 HydrophobicContact CD1-CZ 3.96Å; Y126-F532 HydrophobicContact CE1-CE1 4.42Å; Y126-F532 AromaticContact CE1-CZ 3.83Å; Y126-F532 HydrophobicContact CE1-CZ 3.83Å
127	P	87.3	Confident	90.2	Very high	60 Å²	60	41.2 Å²	41.2	39%	0.39	21%	0.211	S	C	.	.			trans	-67.4	163.8	174.9	25	-27.8	0	0	0	111.3	V129 P130 R131 Y510	P127-V129 VanDerWaalsContact C-N 3.32Å; P127-V129 PolarHBondContact O-N 2.87Å; P127-V129 VanDerWaalsContact O-N 3.15Å; P127-P130 HydrophobicContact CG-CG 3.93Å; P127-P130 WeakPolarHBondContact O-CD 3.45Å; P127-R131 WeakPolarHBondContact O-CB 3.47Å; P127-R131 PolarHBondContact O-N 2.87Å; P127-Y510 VanDerWaalsContact CD-OH 3.31Å; P127-Y510 WeakPolarHBondContact CD-OH 3.48Å
128	K	86.9	Confident	90.2	Very high	158 Å²	158	41 Å²	41	69%	0.687	21%	0.209	S	C	*	.	H	α-helix	trans	-50.8	-45.6	-170	-66.3	-177.3	179.5	177.6	0	113.8	T132	K128-T132 WeakPolarHBondContact O-CG2 3.16Å; K128-T132 PolarHBondContact O-N 3.34Å; K128-T132 PolarHBondContact O-OG1 2.77Å
129	V	89.3	Confident	90.1	Very high	100 Å²	100	41.8 Å²	41.8	61%	0.606	21%	0.213	S	C	*	.	H	α-helix	trans	-69.6	-57.3	-173.8	175.4	0	0	0	0	112.7	P127 R131 T132 L133	P127-V129 VanDerWaalsContact C-N 3.32Å; P127-V129 PolarHBondContact O-N 2.87Å; P127-V129 VanDerWaalsContact O-N 3.15Å; V129-R131 PolarHBondContact O-N 3Å; V129-T132 PolarHBondContact O-N 3.38Å; V129-T132 PolarHBondContact O-OG1 3.12Å; V129-L133 HydrophobicContact CG1-CD1 4.25Å; V129-L133 WeakPolarHBondContact O-CG 3.34Å; V129-L133 PolarHBondContact O-N 3.41Å; V129-L133 VanDerWaalsContact O-N 3.07Å
130	P	88.7	Confident	90.1	Very high	21 Å²	21	45.9 Å²	45.9	14%	0.136	24%	0.235	C	C	.	.	H	α-helix	trans	-57.1	-36.9	174.1	-26.7	35.4	0	0	0	113	P127 L133 L134 L507 Y510	P127-P130 HydrophobicContact CG-CG 3.93Å; P127-P130 WeakPolarHBondContact O-CD 3.45Å; P130-L133 PolarHBondContact O-N 3.04Å; P130-L134 WeakPolarHBondContact O-CB 3.46Å; P130-L134 PolarHBondContact O-N 2.96Å; P130-L507 HydrophobicContact CB-CD1 4.2Å; P130-Y510 HydrophobicContact CB-CD1 4.06Å; P130-Y510 HydrophobicContact CB-CE1 3.66Å; P130-Y510 HydrophobicContact CG-CD1 4.21Å; P130-Y510 HydrophobicContact CG-CE1 3.77Å
131	R	90.4	Very high	90.1	Very high	40 Å²	40	43 Å²	43	15%	0.151	22%	0.221	C	C	.	.	H	α-helix	trans	-61.3	-47.3	177	-179.5	-178.3	69.1	-172.3	12.3	112.6	H123 P127 V129 L134 W135 F387	H123-R131 PolarHBondContact CE1-NH1 3.15Å; H123-R131 PolarHBondContact ND1-NH1 3.29Å; H123-R131 PolarHBondContact NE2-NH1 2.97Å; H123-R131 PolarHBondContact O-NH1 3.27Å; P127-R131 WeakPolarHBondContact O-CB 3.47Å; P127-R131 PolarHBondContact O-N 2.87Å; V129-R131 PolarHBondContact O-N 3Å; R131-L134 PolarHBondContact O-N 2.97Å; R131-W135 PolarHBondContact O-N 3.32Å; R131-F387 HydrophobicContact CG-CD1 3.86Å
132	T	90.3	Very high	90.1	Very high	60 Å²	60	43.1 Å²	43.1	37%	0.368	22%	0.222	S	C	.	.	H	α-helix	trans	-68.8	-37.1	179.4	46.4	0	0	0	0	112.3	K128 V129 L134 L136 L388	K128-T132 WeakPolarHBondContact O-CG2 3.16Å; K128-T132 PolarHBondContact O-N 3.34Å; K128-T132 PolarHBondContact O-OG1 2.77Å; V129-T132 PolarHBondContact O-N 3.38Å; V129-T132 PolarHBondContact O-OG1 3.12Å; T132-L134 VanDerWaalsContact C-N 3.35Å; T132-L136 PolarHBondContact O-N 3.35Å; T132-L388 HydrophobicContact CG2-CD2 4.46Å
133	L	91.8	Very high	90.1	Very high	79 Å²	79	44.4 Å²	44.4	41%	0.414	23%	0.23	S	C	.	.	H	α-helix	trans	-65.1	-42.7	174.3	-68.1	175.8	0	0	0	110.9	V129 P130 L136 T137 L507	V129-L133 HydrophobicContact CG1-CD1 4.25Å; V129-L133 WeakPolarHBondContact O-CG 3.34Å; V129-L133 PolarHBondContact O-N 3.41Å; V129-L133 VanDerWaalsContact O-N 3.07Å; P130-L133 PolarHBondContact O-N 3.04Å; L133-L136 PolarHBondContact O-N 3.5Å; L133-T137 WeakPolarHBondContact O-CG2 3.44Å; L133-T137 PolarHBondContact O-N 3.13Å; L133-T137 PolarHBondContact O-OG1 3.48Å; L133-L507 HydrophobicContact CB-CD1 4.48Å; L133-L507 HydrophobicContact CB-CD2 3.94Å
134	L	91.6	Very high	90.1	Very high	1 Å²	1	43.2 Å²	43.2	1%	0.005	23%	0.225	C	C	.	.	H	α-helix	trans	-62.4	-45.9	177.7	-179.6	57.6	0	0	0	111.2	C122 Y126 P130 R131 T132 L136 T137 I138 F387 F438 P442	C122-L134 HydrophobicContact CB-CD2 4.46Å; Y126-L134 HydrophobicContact CD2-CD2 4.23Å; Y126-L134 HydrophobicContact CE2-CD2 4.17Å; P130-L134 WeakPolarHBondContact O-CB 3.46Å; P130-L134 PolarHBondContact O-N 2.96Å; R131-L134 PolarHBondContact O-N 2.97Å; T132-L134 VanDerWaalsContact C-N 3.35Å; L134-L136 PolarHBondContact O-N 2.76Å; L134-T137 WeakPolarHBondContact CA-OG1 3.4Å; L134-T137 PolarHBondContact O-N 3.42Å; L134-T137 PolarHBondContact O-OG1 3.25Å; L134-I138 HydrophobicContact CD1-CG1 4.36Å; L134-I138 WeakPolarHBondContact O-CG1 3.31Å; L134-I138 PolarHBondContact O-N 2.58Å; L134-I138 VanDerWaalsContact O-N 3.09Å; L134-F387 HydrophobicContact CB-CE1 4.01Å; L134-F387 HydrophobicContact CD2-CE1 3.63Å; L134-F387 HydrophobicContact CD2-CZ 3.73Å; L134-F387 HydrophobicContact CG-CE1 3.62Å; L134-F387 HydrophobicContact CG-CZ 3.67Å; L134-F438 HydrophobicContact CD1-CB 3.56Å; L134-F438 HydrophobicContact CD1-CD1 4.46Å; L134-F438 HydrophobicContact CD1-CG 4.33Å; L134-F438 WeakPolarHBondContact CD1-O 3.49Å; L134-P442 HydrophobicContact CD2-CG 4.01Å
135	W	92.8	Very high	90.2	Very high	57 Å²	57	41.1 Å²	41.1	22%	0.216	21%	0.214	C	C	.	.	H	α-helix	trans	-55.1	-49.7	172.7	170.4	69.6	0	0	0	112.2	R131 T137 I138 E139 M384 F387 L388	R131-W135 PolarHBondContact O-N 3.32Å; W135-T137 VanDerWaalsContact C-N 3.29Å; W135-T137 PolarHBondContact O-N 3.09Å; W135-I138 PolarHBondContact O-N 2.84Å; W135-I138 VanDerWaalsContact O-N 3.13Å; W135-E139 HydrophobicContact CD2-CG 4.16Å; W135-E139 VanDerWaalsContact CE2-CG 3.47Å; W135-E139 HydrophobicContact CG-CG 4.41Å; W135-E139 HydrophobicContact CZ2-CG 3.77Å; W135-E139 VanDerWaalsContact NE1-CG 3.25Å; W135-E139 PolarHBondContact NE1-OE1 3.09Å; W135-E139 WeakPolarHBondContact O-CG 3.31Å; W135-E139 PolarHBondContact O-N 3.15Å; W135-M384 HydrophobicContact CZ2-CE 4.13Å; W135-F387 HydrophobicContact CB-CB 3.83Å; W135-F387 HydrophobicContact CB-CD1 3.94Å; W135-F387 HydrophobicContact CB-CG 3.86Å; W135-F387 HydrophobicContact CG-CB 4.02Å; W135-F387 HydrophobicContact CG-CG 4.42Å; W135-L388 HydrophobicContact CD2-CD1 3.58Å; W135-L388 HydrophobicContact CD2-CD2 4.34Å; W135-L388 HydrophobicContact CD2-CG 3.99Å; W135-L388 HydrophobicContact CE3-CD1 3.9Å; W135-L388 HydrophobicContact CE3-CD2 4.5Å; W135-L388 HydrophobicContact CG-CD1 4.2Å; W135-L388 HydrophobicContact CG-CD2 4.44Å; W135-L388 HydrophobicContact CG-CG 4.09Å; W135-L388 HydrophobicContact CH2-CD1 3.82Å; W135-L388 HydrophobicContact CZ2-CD1 3.5Å; W135-L388 VanDerWaalsContact CZ2-CD1 3.5Å; W135-L388 HydrophobicContact CZ3-CD1 4.01Å
136	L	92.3	Very high	90.4	Very high	103 Å²	103	40.4 Å²	40.4	54%	0.539	21%	0.211	S	C	.	.	H	α-helix	trans	-57.9	-41.4	179.2	-174.6	72	0	0	0	112.1	T132 L133 L134 L140	T132-L136 PolarHBondContact O-N 3.35Å; L133-L136 PolarHBondContact O-N 3.5Å; L134-L136 PolarHBondContact O-N 2.76Å; L136-L140 WeakPolarHBondContact O-CB 3.49Å; L136-L140 PolarHBondContact O-N 3.41Å
137	T	91.9	Very high	90.5	Very high	23 Å²	23	41 Å²	41	14%	0.141	22%	0.215	C	C	.	.	H	α-helix	trans	-66	-36.5	178.5	57.5	0	0	0	0	112.6	L133 L134 W135 A141 L435 F438 L507	L133-T137 WeakPolarHBondContact O-CG2 3.44Å; L133-T137 PolarHBondContact O-N 3.13Å; L133-T137 PolarHBondContact O-OG1 3.48Å; L134-T137 WeakPolarHBondContact CA-OG1 3.4Å; L134-T137 PolarHBondContact O-N 3.42Å; L134-T137 PolarHBondContact O-OG1 3.25Å; W135-T137 VanDerWaalsContact C-N 3.29Å; W135-T137 PolarHBondContact O-N 3.09Å; T137-A141 PolarHBondContact O-N 2.99Å; T137-A141 VanDerWaalsContact O-N 3.11Å; T137-L435 HydrophobicContact CG2-CD2 4.32Å; T137-F438 HydrophobicContact CG2-CD2 3.85Å; T137-F438 HydrophobicContact CG2-CE2 3.83Å; T137-F438 HydrophobicContact CG2-CG 4.42Å; T137-F438 HydrophobicContact CG2-CZ 4.43Å; T137-L507 HydrophobicContact CG2-CD2 4.46Å
138	I	92.3	Very high	90.6	Very high	0 Å²	0	38.2 Å²	38.2	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-76.7	-38.7	178.5	-58.7	-55.1	0	0	0	111.4	L134 W135 L140 A141 I142 P251 H252 Y255 V383 F438 A439	L134-I138 HydrophobicContact CD1-CG1 4.36Å; L134-I138 WeakPolarHBondContact O-CG1 3.31Å; L134-I138 PolarHBondContact O-N 2.58Å; L134-I138 VanDerWaalsContact O-N 3.09Å; W135-I138 PolarHBondContact O-N 2.84Å; W135-I138 VanDerWaalsContact O-N 3.13Å; I138-L140 VanDerWaalsContact C-N 3.28Å; I138-L140 PolarHBondContact O-N 2.78Å; I138-A141 WeakPolarHBondContact O-CB 3.29Å; I138-A141 PolarHBondContact O-N 3.13Å; I138-A141 VanDerWaalsContact O-N 3.13Å; I138-I142 HydrophobicContact CG2-CD1 4.13Å; I138-I142 WeakPolarHBondContact O-CG1 3.22Å; I138-I142 PolarHBondContact O-N 3.48Å; I138-P251 HydrophobicContact CD1-CB 4.2Å; I138-H252 HydrophobicContact CG2-CB 4.46Å; I138-Y255 HydrophobicContact CD1-CD2 4.3Å; I138-Y255 HydrophobicContact CD1-CE2 3.52Å; I138-Y255 HydrophobicContact CG1-CD2 4.38Å; I138-Y255 HydrophobicContact CG1-CE2 3.66Å; I138-Y255 HydrophobicContact CG2-CD2 4.06Å; I138-Y255 HydrophobicContact CG2-CE2 4.19Å; I138-V383 HydrophobicContact CB-CG1 4.13Å; I138-V383 HydrophobicContact CG2-CB 4.34Å; I138-V383 HydrophobicContact CG2-CG1 3.81Å; I138-V383 HydrophobicContact CG2-CG2 3.62Å; I138-F438 HydrophobicContact CD1-CB 4.19Å; I138-A439 HydrophobicContact CD1-CB 4.3Å
139	E	91.6	Very high	90.7	Very high	18 Å²	18	30.8 Å²	30.8	8%	0.084	16%	0.164	C	C	.	.	H	α-helix	trans	-59.4	-41.4	171	-72	-64.3	162.8	0	0	111.5	W135 A141 I142 V143 M384	W135-E139 HydrophobicContact CD2-CG 4.16Å; W135-E139 VanDerWaalsContact CE2-CG 3.47Å; W135-E139 HydrophobicContact CG-CG 4.41Å; W135-E139 HydrophobicContact CZ2-CG 3.77Å; W135-E139 VanDerWaalsContact NE1-CG 3.25Å; W135-E139 PolarHBondContact NE1-OE1 3.09Å; W135-E139 WeakPolarHBondContact O-CG 3.31Å; W135-E139 PolarHBondContact O-N 3.15Å; E139-A141 VanDerWaalsContact C-N 3.3Å; E139-A141 PolarHBondContact O-N 3.33Å; E139-I142 PolarHBondContact O-N 2.89Å; E139-I142 VanDerWaalsContact O-N 3.16Å; E139-V143 WeakPolarHBondContact O-CG2 3.47Å; E139-V143 PolarHBondContact O-N 3.05Å; E139-M384 WeakPolarHBondContact OE1-CG 3.33Å
140	L	91.4	Very high	90.8	Very high	86 Å²	86	26 Å²	26	45%	0.45	14%	0.135	S	C	.	.	H	α-helix	trans	-61.4	-39.2	174.7	-176	63.8	0	0	0	111.8	L136 I138 I142 G144 L431 L435	L136-L140 WeakPolarHBondContact O-CB 3.49Å; L136-L140 PolarHBondContact O-N 3.41Å; I138-L140 VanDerWaalsContact C-N 3.28Å; I138-L140 PolarHBondContact O-N 2.78Å; L140-I142 VanDerWaalsContact C-N 3.34Å; L140-G144 PolarHBondContact O-N 2.91Å; L140-L431 HydrophobicContact CD2-CD1 4.19Å; L140-L431 HydrophobicContact CG-CD2 4.31Å; L140-L435 HydrophobicContact CB-CD1 4.37Å; L140-L435 HydrophobicContact CD2-CD1 4.37Å; L140-L435 HydrophobicContact CG-CD1 4.24Å
141	A	91.5	Very high	90.8	Very high	0 Å²	0	25.2 Å²	25.2	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-63.8	-39.4	174.2	0	0	0	0	0	112	T137 I138 E139 G144 S145 P251 Q432 L435	T137-A141 PolarHBondContact O-N 2.99Å; T137-A141 VanDerWaalsContact O-N 3.11Å; I138-A141 WeakPolarHBondContact O-CB 3.29Å; I138-A141 PolarHBondContact O-N 3.13Å; I138-A141 VanDerWaalsContact O-N 3.13Å; E139-A141 VanDerWaalsContact C-N 3.3Å; E139-A141 PolarHBondContact O-N 3.33Å; A141-G144 PolarHBondContact O-N 3.3Å; A141-S145 PolarHBondContact O-N 3.14Å; A141-P251 HydrophobicContact CB-CB 4.42Å; A141-P251 HydrophobicContact CB-CG 4.33Å; A141-Q432 PolarHBondContact O-NE2 3.3Å; A141-L435 HydrophobicContact CB-CB 4.35Å; A141-L435 HydrophobicContact CB-CD1 3.69Å
142	I	91.1	Very high	90.8	Very high	3 Å²	3	23.3 Å²	23.3	2%	0.015	12%	0.123	C	C	.	.	H	α-helix	trans	-67.4	-49	178.7	-66.8	161.5	0	0	0	110.5	I138 E139 L140 G144 S145 D146 H252 A379 V383	I138-I142 HydrophobicContact CG2-CD1 4.13Å; I138-I142 WeakPolarHBondContact O-CG1 3.22Å; I138-I142 PolarHBondContact O-N 3.48Å; E139-I142 PolarHBondContact O-N 2.89Å; E139-I142 VanDerWaalsContact O-N 3.16Å; L140-I142 VanDerWaalsContact C-N 3.34Å; I142-G144 PolarHBondContact O-N 3.07Å; I142-S145 PolarHBondContact O-N 3.14Å; I142-D146 VanDerWaalsContact O-CB 3.25Å; I142-D146 WeakPolarHBondContact O-CB 3.47Å; I142-D146 PolarHBondContact O-N 3.15Å; I142-H252 HydrophobicContact CD1-CB 4.16Å; I142-H252 HydrophobicContact CG1-CB 3.49Å; I142-H252 VanDerWaalsContact CG1-CB 3.49Å; I142-A379 HydrophobicContact CD1-CB 4.27Å; I142-A379 HydrophobicContact CG1-CB 4.37Å; I142-V383 HydrophobicContact CD1-CB 4.24Å; I142-V383 HydrophobicContact CD1-CG1 4.49Å; I142-V383 HydrophobicContact CD1-CG2 4.13Å
143	V	90.6	Very high	90.9	Very high	28 Å²	28	20.5 Å²	20.5	17%	0.17	11%	0.105	C	C	.	.	H	α-helix	trans	-60.2	-38.6	175.7	174.1	0	0	0	0	110.8	E139 D146 M147 C404 A405	E139-V143 WeakPolarHBondContact O-CG2 3.47Å; E139-V143 PolarHBondContact O-N 3.05Å; V143-D146 WeakPolarHBondContact O-CB 3.44Å; V143-D146 PolarHBondContact O-N 2.82Å; V143-M147 HydrophobicContact CG1-SD 4.42Å; V143-M147 VanDerWaalsContact O-CG 3.3Å; V143-M147 WeakPolarHBondContact O-CG 3.48Å; V143-M147 PolarHBondContact O-N 2.92Å; V143-C404 HydrophobicContact CG1-CB 4.39Å; V143-C404 HydrophobicContact CG2-CB 4.37Å; V143-A405 HydrophobicContact CG1-CB 4.35Å
144	G	89.9	Confident	90.8	Very high	2 Å²	2	16.8 Å²	16.8	2%	0.021	9%	0.086	C	C	.	.	H	α-helix	trans	-59.8	-51.1	175.8	0	0	0	0	0	112.4	L140 A141 I142 M147 Q148	L140-G144 PolarHBondContact O-N 2.91Å; A141-G144 PolarHBondContact O-N 3.3Å; I142-G144 PolarHBondContact O-N 3.07Å; G144-M147 WeakPolarHBondContact O-CB 3.24Å; G144-M147 PolarHBondContact O-N 2.87Å; G144-Q148 WeakPolarHBondContact O-CG 3.27Å; G144-Q148 PolarHBondContact O-N 3.45Å
145	S	89.6	Confident	90.8	Very high	1 Å²	1	17.1 Å²	17.1	1%	0.007	9%	0.088	C	C	.	.	H	α-helix	trans	-65.4	-38.8	179.1	173.8	0	0	0	0	112.4	A141 I142 M147 Q148 E149 H252	A141-S145 PolarHBondContact O-N 3.14Å; I142-S145 PolarHBondContact O-N 3.14Å; S145-M147 VanDerWaalsContact C-N 3.32Å; S145-M147 PolarHBondContact O-N 3.3Å; S145-Q148 WeakPolarHBondContact O-CB 3.38Å; S145-Q148 PolarHBondContact O-N 2.97Å; S145-Q148 VanDerWaalsContact O-N 3.1Å; S145-E149 PolarHBondContact O-N 3.35Å; S145-E149 VanDerWaalsContact O-N 3.09Å; S145-H252 PolarHBondContact OG-CE1 3.27Å
146	D	90.3	Very high	90.8	Very high	3 Å²	3	14.4 Å²	14.4	2%	0.016	8%	0.077	C	C	.	.	H	α-helix	trans	-55	-46	172.2	-178	-13.1	0	0	0	111.6	I142 V143 Q148 E149 V150 R402 A405	I142-D146 VanDerWaalsContact O-CB 3.25Å; I142-D146 WeakPolarHBondContact O-CB 3.47Å; I142-D146 PolarHBondContact O-N 3.15Å; V143-D146 WeakPolarHBondContact O-CB 3.44Å; V143-D146 PolarHBondContact O-N 2.82Å; D146-Q148 PolarHBondContact O-N 3.39Å; D146-E149 WeakPolarHBondContact O-CB 3.47Å; D146-E149 PolarHBondContact O-N 3.3Å; D146-V150 WeakPolarHBondContact O-CG2 3.17Å; D146-V150 PolarHBondContact O-N 3.32Å; D146-R402 IonicContact OD1-CZ 2.77Å; D146-R402 IonicContact OD1-NE 2.67Å; D146-R402 PolarHBondContact OD1-NE 3.32Å; D146-R402 IonicContact OD1-NH1 3.04Å; D146-R402 PolarHBondContact OD1-NH1 3Å; D146-R402 IonicContact OD1-NH2 3.64Å; D146-R402 PolarHBondContact OD1-NH2 2.97Å; D146-R402 IonicContact OD2-CZ 2.87Å; D146-R402 IonicContact OD2-NE 2.76Å; D146-R402 PolarHBondContact OD2-NE 3.31Å; D146-R402 IonicContact OD2-NH1 2.97Å; D146-R402 IonicContact OD2-NH2 3.1Å; D146-R402 PolarHBondContact OD2-NH2 3.27Å; D146-A405 HydrophobicContact CB-CB 3.82Å; D146-A405 VanDerWaalsContact OD1-CB 3.27Å; D146-A405 WeakPolarHBondContact OD1-CB 3.35Å; D146-A405 WeakPolarHBondContact OD2-CB 3.19Å
147	M	88.9	Confident	90.8	Very high	18 Å²	18	11.8 Å²	11.8	9%	0.089	6%	0.062	C	C	.	.	H	α-helix	trans	-58.9	-43.4	174.6	-70.3	173.5	64.2	0	0	112.4	V143 G144 S145 E149 V150 I151 A405 P408 L424 L428	V143-M147 HydrophobicContact CG1-SD 4.42Å; V143-M147 VanDerWaalsContact O-CG 3.3Å; V143-M147 WeakPolarHBondContact O-CG 3.48Å; V143-M147 PolarHBondContact O-N 2.92Å; G144-M147 WeakPolarHBondContact O-CB 3.24Å; G144-M147 PolarHBondContact O-N 2.87Å; S145-M147 VanDerWaalsContact C-N 3.32Å; S145-M147 PolarHBondContact O-N 3.3Å; M147-E149 PolarHBondContact O-N 3.28Å; M147-V150 PolarHBondContact O-N 2.83Å; M147-I151 WeakPolarHBondContact O-CD1 3.07Å; M147-I151 WeakPolarHBondContact O-CG1 3.44Å; M147-I151 PolarHBondContact O-N 3.49Å; M147-A405 HydrophobicContact CG-CB 3.84Å; M147-P408 HydrophobicContact CE-CB 4.1Å; M147-P408 HydrophobicContact CE-CG 3.91Å; M147-P408 HydrophobicContact SD-CG 3.94Å; M147-L424 HydrophobicContact CE-CD1 4.16Å; M147-L424 HydrophobicContact CE-CD2 3.76Å; M147-L424 HydrophobicContact CE-CG 4.26Å; M147-L428 HydrophobicContact CB-CD1 3.66Å; M147-L428 HydrophobicContact CE-CD1 4.31Å; M147-L428 HydrophobicContact CE-CD2 4.5Å; M147-L428 HydrophobicContact SD-CD2 4.29Å
148	Q	89.6	Confident	90.7	Very high	2 Å²	2	11.2 Å²	11.2	1%	0.009	6%	0.058	C	C	.	.	H	α-helix	trans	-60.9	-37.8	179	-50.8	-173.9	-79.6	0	0	111.2	G144 S145 D146 G152 N425 L428 N429	G144-Q148 WeakPolarHBondContact O-CG 3.27Å; G144-Q148 PolarHBondContact O-N 3.45Å; S145-Q148 WeakPolarHBondContact O-CB 3.38Å; S145-Q148 PolarHBondContact O-N 2.97Å; S145-Q148 VanDerWaalsContact O-N 3.1Å; D146-Q148 PolarHBondContact O-N 3.39Å; Q148-G152 PolarHBondContact O-N 3.21Å; Q148-N425 VanDerWaalsContact CB-OD1 3.29Å; Q148-N425 WeakPolarHBondContact CB-OD1 3.47Å; Q148-N425 VanDerWaalsContact CD-OD1 3.29Å; Q148-N425 WeakPolarHBondContact CG-OD1 3.46Å; Q148-N425 PolarHBondContact NE2-OD1 2.98Å; Q148-L428 HydrophobicContact CG-CB 3.77Å; Q148-L428 HydrophobicContact CG-CD1 3.65Å; Q148-L428 HydrophobicContact CG-CG 4.33Å; Q148-N429 PolarHBondContact NE2-OD1 3.4Å
149	E	89.8	Confident	90.6	Very high	1 Å²	1	11.2 Å²	11.2	1%	0.005	6%	0.058	C	C	.	.	H	α-helix	trans	-69.1	-42.9	177.2	126.1	174.6	-95.3	0	0	112.7	S145 D146 M147 I151 G152 T153 S372 T373 R402	S145-E149 PolarHBondContact O-N 3.35Å; S145-E149 VanDerWaalsContact O-N 3.09Å; D146-E149 WeakPolarHBondContact O-CB 3.47Å; D146-E149 PolarHBondContact O-N 3.3Å; M147-E149 PolarHBondContact O-N 3.28Å; E149-I151 PolarHBondContact O-N 3.49Å; E149-G152 PolarHBondContact O-N 3.06Å; E149-T153 WeakPolarHBondContact O-CB 3.46Å; E149-T153 PolarHBondContact O-N 3.17Å; E149-T153 PolarHBondContact O-OG1 3.4Å; E149-S372 VanDerWaalsContact OE1-C 3.28Å; E149-S372 WeakPolarHBondContact OE1-CB 3.32Å; E149-T373 WeakPolarHBondContact OE1-CA 3.34Å; E149-T373 WeakPolarHBondContact OE1-CB 3.41Å; E149-T373 PolarHBondContact OE1-N 3.47Å; E149-T373 PolarHBondContact OE1-OG1 2.91Å; E149-T373 WeakPolarHBondContact OE2-CA 3.44Å; E149-T373 WeakPolarHBondContact OE2-CB 3.23Å; E149-T373 PolarHBondContact OE2-N 3.02Å; E149-R402 IonicContact OE2-CZ 3.91Å; E149-R402 VanDerWaalsContact OE2-CZ 3.26Å; E149-R402 IonicContact OE2-NH1 3.07Å; E149-R402 PolarHBondContact OE2-NH1 3.04Å; E149-R402 IonicContact OE2-NH2 2.7Å; E149-R402 PolarHBondContact OE2-NH2 3.04Å
150	V	90.1	Very high	90.7	Very high	1 Å²	1	13 Å²	13	1%	0.006	7%	0.068	C	C	.	.	H	α-helix	trans	-63.6	-39.5	-179.7	170.9	0	0	0	0	108.9	D146 M147 A154 V171 T174 I406 T409	D146-V150 WeakPolarHBondContact O-CG2 3.17Å; D146-V150 PolarHBondContact O-N 3.32Å; M147-V150 PolarHBondContact O-N 2.83Å; V150-A154 WeakPolarHBondContact O-CB 3.39Å; V150-A154 PolarHBondContact O-N 3.49Å; V150-V171 HydrophobicContact CG1-CB 4.19Å; V150-V171 HydrophobicContact CG1-CG1 3.6Å; V150-V171 HydrophobicContact CG1-CG2 4.05Å; V150-T174 HydrophobicContact CG1-CG2 4.31Å; V150-I406 HydrophobicContact CG1-CG1 4.48Å; V150-I406 HydrophobicContact CG2-CG1 4.21Å; V150-T409 HydrophobicContact CG1-CG2 3.92Å
151	I	89.1	Confident	90.6	Very high	4 Å²	4	9.8 Å²	9.8	2%	0.021	5%	0.052	C	C	.	.	H	α-helix	trans	-61.6	-52	172.5	-66.1	165.3	0	0	0	110.5	M147 E149 T153 A154 I155 T409 L421 L424 L428	M147-I151 WeakPolarHBondContact O-CD1 3.07Å; M147-I151 WeakPolarHBondContact O-CG1 3.44Å; M147-I151 PolarHBondContact O-N 3.49Å; E149-I151 PolarHBondContact O-N 3.49Å; I151-T153 PolarHBondContact O-N 2.97Å; I151-A154 PolarHBondContact O-N 3.19Å; I151-I155 HydrophobicContact CG2-CD1 3.73Å; I151-I155 WeakPolarHBondContact O-CB 3.47Å; I151-I155 VanDerWaalsContact O-CG1 3.28Å; I151-I155 WeakPolarHBondContact O-CG1 3.46Å; I151-I155 PolarHBondContact O-N 2.78Å; I151-T409 HydrophobicContact CG1-CG2 3.73Å; I151-L421 HydrophobicContact CG1-CD2 4.28Å; I151-L424 HydrophobicContact CD1-CD2 4.03Å; I151-L424 HydrophobicContact CD1-CG 4.33Å; I151-L428 HydrophobicContact CD1-CD1 4.39Å
152	G	91	Very high	90.2	Very high	0 Å²	0	11.8 Å²	11.8	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-59.5	-44.2	-179.9	0	0	0	0	0	113.3	Q148 E149 I155 A156 L365	Q148-G152 PolarHBondContact O-N 3.21Å; E149-G152 PolarHBondContact O-N 3.06Å; G152-I155 PolarHBondContact O-N 3.04Å; G152-A156 WeakPolarHBondContact O-CB 3.31Å; G152-A156 PolarHBondContact O-N 3.5Å; G152-L365 VanDerWaalsContact O-CD2 3.3Å; G152-L365 WeakPolarHBondContact O-CD2 3.33Å; G152-L365 WeakPolarHBondContact O-CG 3.47Å
153	T	91.4	Very high	89.8	Confident	0 Å²	0	13.5 Å²	13.5	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-66.5	-41.6	177.7	-60.9	0	0	0	0	111.8	E149 I151 I155 A156 F157 T174 L366 G369	E149-T153 WeakPolarHBondContact O-CB 3.46Å; E149-T153 PolarHBondContact O-N 3.17Å; E149-T153 PolarHBondContact O-OG1 3.4Å; I151-T153 PolarHBondContact O-N 2.97Å; T153-I155 VanDerWaalsContact C-N 3.34Å; T153-I155 PolarHBondContact O-N 3.3Å; T153-A156 WeakPolarHBondContact O-CB 3.32Å; T153-A156 PolarHBondContact O-N 3.17Å; T153-F157 HydrophobicContact CG2-CD2 3.86Å; T153-F157 HydrophobicContact CG2-CE2 3.55Å; T153-F157 VanDerWaalsContact O-CD2 3.27Å; T153-F157 WeakPolarHBondContact O-CD2 3.39Å; T153-F157 PolarHBondContact O-N 2.82Å; T153-T174 HydrophobicContact CG2-CG2 3.62Å; T153-L366 HydrophobicContact CG2-CD1 3.88Å; T153-G369 WeakPolarHBondContact OG1-CA 3.31Å; T153-G369 PolarHBondContact OG1-O 3.27Å
154	A	90.9	Very high	89.6	Confident	2 Å²	2	22.1 Å²	22.1	2%	0.017	12%	0.117	C	C	.	.	H	α-helix	trans	-63.6	-40.6	175.8	0	0	0	0	0	112.1	V150 I151 F157 N158 V171	V150-A154 WeakPolarHBondContact O-CB 3.39Å; V150-A154 PolarHBondContact O-N 3.49Å; I151-A154 PolarHBondContact O-N 3.19Å; A154-F157 PolarHBondContact O-N 2.71Å; A154-N158 WeakPolarHBondContact O-CB 3.47Å; A154-N158 PolarHBondContact O-N 3.13Å; A154-V171 HydrophobicContact CB-CB 4.5Å; A154-V171 HydrophobicContact CB-CG2 3.6Å
155	I	90	Very high	89.5	Confident	7 Å²	7	24.5 Å²	24.5	4%	0.036	13%	0.129	C	C	.	.	H	α-helix	trans	-62.5	-44.4	173.4	-71.9	169.5	0	0	0	110.5	I151 G152 T153 F157 N158 L159 L167 I342 Y343 L365	I151-I155 HydrophobicContact CG2-CD1 3.73Å; I151-I155 WeakPolarHBondContact O-CB 3.47Å; I151-I155 VanDerWaalsContact O-CG1 3.28Å; I151-I155 WeakPolarHBondContact O-CG1 3.46Å; I151-I155 PolarHBondContact O-N 2.78Å; G152-I155 PolarHBondContact O-N 3.04Å; T153-I155 VanDerWaalsContact C-N 3.34Å; T153-I155 PolarHBondContact O-N 3.3Å; I155-F157 PolarHBondContact O-N 2.96Å; I155-N158 PolarHBondContact O-N 3.24Å; I155-L159 HydrophobicContact CG2-CD1 3.98Å; I155-L159 HydrophobicContact CG2-CG 4.43Å; I155-L159 WeakPolarHBondContact O-CG 3.37Å; I155-L159 PolarHBondContact O-N 3.4Å; I155-L167 HydrophobicContact CG1-CD2 4.1Å; I155-I342 HydrophobicContact CD1-CB 4.46Å; I155-I342 HydrophobicContact CG2-CG2 4.07Å; I155-Y343 HydrophobicContact CG2-CD2 4.1Å; I155-L365 HydrophobicContact CB-CD2 4.22Å; I155-L365 HydrophobicContact CG2-CD2 3.79Å
156	A	93.1	Very high	89.4	Confident	0 Å²	0	26.9 Å²	26.9	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-58.5	-47	177	0	0	0	0	0	111.9	G152 T153 N158 L159 L160 A362 L365 L366	G152-A156 WeakPolarHBondContact O-CB 3.31Å; G152-A156 PolarHBondContact O-N 3.5Å; T153-A156 WeakPolarHBondContact O-CB 3.32Å; T153-A156 PolarHBondContact O-N 3.17Å; A156-N158 VanDerWaalsContact C-N 3.34Å; A156-N158 PolarHBondContact O-N 3.01Å; A156-L159 PolarHBondContact O-N 3.45Å; A156-L160 WeakPolarHBondContact O-CB 3.27Å; A156-L160 VanDerWaalsContact O-CG 3.25Å; A156-L160 WeakPolarHBondContact O-CG 3.46Å; A156-L160 PolarHBondContact O-N 2.92Å; A156-A362 WeakPolarHBondContact CB-O 3.47Å; A156-L365 HydrophobicContact CB-CB 4.24Å; A156-L365 HydrophobicContact CB-CD2 3.99Å; A156-L365 HydrophobicContact CB-CG 4.11Å; A156-L366 HydrophobicContact CB-CB 3.91Å; A156-L366 HydrophobicContact CB-CD1 4.33Å
157	F	92.8	Very high	89.2	Confident	48 Å²	48	27.7 Å²	27.7	21%	0.211	15%	0.148	C	C	.	.	H	α-helix	trans	-63.4	-38	175.7	-77.7	-58	0	0	0	113	T153 A154 I155 S161 I173 L366	T153-F157 HydrophobicContact CG2-CD2 3.86Å; T153-F157 HydrophobicContact CG2-CE2 3.55Å; T153-F157 VanDerWaalsContact O-CD2 3.27Å; T153-F157 WeakPolarHBondContact O-CD2 3.39Å; T153-F157 PolarHBondContact O-N 2.82Å; A154-F157 PolarHBondContact O-N 2.71Å; I155-F157 PolarHBondContact O-N 2.96Å; F157-S161 VanDerWaalsContact O-CB 3.23Å; F157-S161 WeakPolarHBondContact O-CB 3.42Å; F157-S161 PolarHBondContact O-N 3.03Å; F157-S161 PolarHBondContact O-OG 3.11Å; F157-I173 HydrophobicContact CD2-CG2 4.17Å; F157-I173 HydrophobicContact CE1-CG2 4.46Å; F157-I173 HydrophobicContact CE2-CB 4.33Å; F157-I173 HydrophobicContact CE2-CG2 3.58Å; F157-I173 HydrophobicContact CZ-CG2 3.75Å; F157-L366 HydrophobicContact CE1-CD1 4.33Å; F157-L366 HydrophobicContact CE2-CD1 4.03Å; F157-L366 HydrophobicContact CZ-CD1 3.9Å
158	N	90.6	Very high	89.1	Confident	12 Å²	12	32.8 Å²	32.8	6%	0.064	17%	0.167	C	C	.	.	H	α-helix	trans	-62.8	-45.2	175.9	-175	-93.6	0	0	0	111.4	A154 I155 A156 S161 A162 G163 I165 L167 Y343	A154-N158 WeakPolarHBondContact O-CB 3.47Å; A154-N158 PolarHBondContact O-N 3.13Å; I155-N158 PolarHBondContact O-N 3.24Å; A156-N158 VanDerWaalsContact C-N 3.34Å; A156-N158 PolarHBondContact O-N 3.01Å; N158-S161 PolarHBondContact O-OG 3.31Å; N158-A162 PolarHBondContact O-N 2.84Å; N158-G163 PolarHBondContact O-N 3.34Å; N158-I165 PolarHBondContact ND2-O 3.22Å; N158-L167 HydrophobicContact CB-CD2 4.01Å; N158-Y343 WeakPolarHBondContact OD1-CE2 3.25Å
159	L	90.3	Very high	89	Confident	0 Å²	0	33.3 Å²	33.3	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-66.9	-47.2	177.8	-69.6	174.2	0	0	0	112.1	I155 A156 S161 A162 Y343 V347 L358 A362	I155-L159 HydrophobicContact CG2-CD1 3.98Å; I155-L159 HydrophobicContact CG2-CG 4.43Å; I155-L159 WeakPolarHBondContact O-CG 3.37Å; I155-L159 PolarHBondContact O-N 3.4Å; A156-L159 PolarHBondContact O-N 3.45Å; L159-S161 VanDerWaalsContact C-N 3.28Å; L159-S161 PolarHBondContact O-N 3.4Å; L159-A162 PolarHBondContact O-N 3.45Å; L159-A162 VanDerWaalsContact O-N 3.1Å; L159-Y343 HydrophobicContact CD1-CD2 4.41Å; L159-Y343 HydrophobicContact CD2-CD2 3.68Å; L159-Y343 HydrophobicContact CD2-CE2 3.49Å; L159-Y343 VanDerWaalsContact CD2-CE2 3.49Å; L159-Y343 HydrophobicContact CG-CD2 3.95Å; L159-Y343 HydrophobicContact CG-CE2 4.07Å; L159-V347 HydrophobicContact CD2-CG2 4.07Å; L159-L358 HydrophobicContact CB-CD2 4.18Å; L159-L358 HydrophobicContact CD2-CD1 4.45Å; L159-L358 HydrophobicContact CD2-CD2 4.48Å; L159-L358 HydrophobicContact CD2-CG 4.46Å; L159-A362 HydrophobicContact CB-CB 3.77Å; L159-A362 HydrophobicContact CD1-CB 4.39Å
160	L	92.4	Very high	88.9	Confident	54 Å²	54	33.2 Å²	33.2	28%	0.283	17%	0.172	S	C	.	.	H	α-helix	trans	-61.1	-36.1	178.6	-72.8	173	0	0	0	112.7	A156 A162 Y359 A362 I363 L366	A156-L160 WeakPolarHBondContact O-CB 3.27Å; A156-L160 VanDerWaalsContact O-CG 3.25Å; A156-L160 WeakPolarHBondContact O-CG 3.46Å; A156-L160 PolarHBondContact O-N 2.92Å; L160-A162 VanDerWaalsContact C-N 3.25Å; L160-A162 PolarHBondContact O-N 3.03Å; L160-Y359 HydrophobicContact CD2-CD1 4.14Å; L160-A362 HydrophobicContact CD2-CB 3.78Å; L160-A362 HydrophobicContact CG-CB 3.75Å; L160-I363 HydrophobicContact CD2-CG1 4Å; L160-L366 HydrophobicContact CD1-CD2 3.98Å
161	S	89.6	Confident	88.9	Confident	19 Å²	19	33.3 Å²	33.3	13%	0.133	17%	0.172	C	C	.	.	T	Hydrogen-bonded Turn	trans	-84	2.6	179.8	67.2	0	0	0	0	114	F157 N158 L159 G163 R164 I165	F157-S161 VanDerWaalsContact O-CB 3.23Å; F157-S161 WeakPolarHBondContact O-CB 3.42Å; F157-S161 PolarHBondContact O-N 3.03Å; F157-S161 PolarHBondContact O-OG 3.11Å; N158-S161 PolarHBondContact O-OG 3.31Å; L159-S161 VanDerWaalsContact C-N 3.28Å; L159-S161 PolarHBondContact O-N 3.4Å; S161-G163 VanDerWaalsContact C-N 3.26Å; S161-G163 PolarHBondContact O-N 3.4Å; S161-R164 WeakPolarHBondContact O-CB 3.46Å; S161-R164 VanDerWaalsContact O-CG 3.31Å; S161-R164 WeakPolarHBondContact O-CG 3.38Å; S161-R164 PolarHBondContact O-N 3.43Å; S161-I165 WeakPolarHBondContact OG-CB 3.39Å; S161-I165 PolarHBondContact OG-N 3.47Å
162	A	83.9	Confident	88.8	Confident	42 Å²	42	36.7 Å²	36.7	35%	0.347	19%	0.19	S	C	.	.	T	Hydrogen-bonded Turn	trans	53.2	42.7	-172.3	0	0	0	0	0	112.5	N158 L159 L160 R164 Y327	N158-A162 PolarHBondContact O-N 2.84Å; L159-A162 PolarHBondContact O-N 3.45Å; L159-A162 VanDerWaalsContact O-N 3.1Å; L160-A162 VanDerWaalsContact C-N 3.25Å; L160-A162 PolarHBondContact O-N 3.03Å; A162-R164 VanDerWaalsContact C-N 3.3Å; A162-R164 PolarHBondContact O-N 3.12Å; A162-Y327 WeakPolarHBondContact CA-OH 3.42Å
163	G	81.6	Confident	88.8	Confident	39 Å²	39	39.7 Å²	39.7	40%	0.402	21%	0.205	S	C	.	.	T	Hydrogen-bonded Turn	trans	78.8	2.8	179.2	0	0	0	0	0	115.5	N158 S161	N158-G163 PolarHBondContact O-N 3.34Å; S161-G163 VanDerWaalsContact C-N 3.26Å; S161-G163 PolarHBondContact O-N 3.4Å
164	R	86.4	Confident	88.6	Confident	210 Å²	210	39.7 Å²	39.7	79%	0.792	21%	0.206	S	C	*	.	S	Bend	trans	-68.3	-35.1	176.3	-67.9	-172.3	-174	98.9	-4.2	112.8	S161 A162 P166	S161-R164 WeakPolarHBondContact O-CB 3.46Å; S161-R164 VanDerWaalsContact O-CG 3.31Å; S161-R164 WeakPolarHBondContact O-CG 3.38Å; S161-R164 PolarHBondContact O-N 3.43Å; A162-R164 VanDerWaalsContact C-N 3.3Å; A162-R164 PolarHBondContact O-N 3.12Å; R164-P166 WeakPolarHBondContact O-CD 3.43Å
165	I	88.2	Confident	88.3	Confident	52 Å²	52	42.6 Å²	42.6	27%	0.267	22%	0.22	S	C	.	.	S	Bend	trans	-93	111.7	174.3	-59	174.5	0	0	0	107.3	N158 S161 I173	N158-I165 PolarHBondContact ND2-O 3.22Å; S161-I165 WeakPolarHBondContact OG-CB 3.39Å; S161-I165 PolarHBondContact OG-N 3.47Å; I165-I173 HydrophobicContact CD1-CD1 4.17Å; I165-I173 HydrophobicContact CG2-CD1 4.02Å
166	P	87.7	Confident	88.1	Confident	50 Å²	50	46.8 Å²	46.8	33%	0.325	25%	0.246	S	C	.	.			trans	-66.8	158.4	175.2	30.3	-35.3	0	0	0	110.4	R164 W168 G169 G170	R164-P166 WeakPolarHBondContact O-CD 3.43Å; P166-W168 VanDerWaalsContact C-N 3.34Å; P166-W168 HydrophobicContact CB-CG 4.48Å; P166-W168 HydrophobicContact CG-CD2 4.12Å; P166-W168 VanDerWaalsContact CG-CE2 3.41Å; P166-W168 HydrophobicContact CG-CG 4.39Å; P166-W168 HydrophobicContact CG-CZ2 3.68Å; P166-W168 VanDerWaalsContact CG-NE1 3.3Å; P166-W168 PolarHBondContact O-N 3.42Å; P166-G169 CarbonylContact O-C 3.59Å; P166-G169 WeakPolarHBondContact O-CA 3.45Å; P166-G169 PolarHBondContact O-N 3.18Å; P166-G170 PolarHBondContact O-N 3.4Å
167	L	85.5	Confident	87.5	Confident	21 Å²	21	47.3 Å²	47.3	11%	0.11	25%	0.249	C	C	.	.	H	α-helix	trans	-55	-46.2	-177	-64.7	168.8	0	0	0	113	I155 N158 G169 G170 V171 L418 L421	I155-L167 HydrophobicContact CG1-CD2 4.1Å; N158-L167 HydrophobicContact CB-CD2 4.01Å; L167-G169 PolarHBondContact O-N 2.86Å; L167-G170 CarbonylContact O-C 3.58Å; L167-G170 WeakPolarHBondContact O-CA 3.01Å; L167-G170 PolarHBondContact O-N 3.47Å; L167-V171 WeakPolarHBondContact O-CG2 3.5Å; L167-V171 PolarHBondContact O-N 3.47Å; L167-L418 HydrophobicContact CD1-CD2 3.18Å; L167-L418 HydrophobicContact CD1-CG 3.68Å; L167-L418 HydrophobicContact CD2-CD2 4.21Å; L167-L418 HydrophobicContact CG-CD2 4.1Å; L167-L421 HydrophobicContact CB-CD1 4.37Å; L167-L421 HydrophobicContact CD1-CD1 3.39Å; L167-L421 HydrophobicContact CG-CD1 4.43Å
168	W	87	Confident	86.8	Confident	125 Å²	125	45.2 Å²	45.2	47%	0.473	24%	0.24	S	C	.	.	H	α-helix	trans	-58.8	-34.1	176.8	66.1	-99.6	0	0	0	111.8	P166 V171 L172 A413 V414	P166-W168 VanDerWaalsContact C-N 3.34Å; P166-W168 HydrophobicContact CB-CG 4.48Å; P166-W168 HydrophobicContact CG-CD2 4.12Å; P166-W168 VanDerWaalsContact CG-CE2 3.41Å; P166-W168 HydrophobicContact CG-CG 4.39Å; P166-W168 HydrophobicContact CG-CZ2 3.68Å; P166-W168 VanDerWaalsContact CG-NE1 3.3Å; P166-W168 PolarHBondContact O-N 3.42Å; W168-V171 PolarHBondContact O-N 3.41Å; W168-L172 HydrophobicContact CE3-CD1 3.79Å; W168-L172 HydrophobicContact CZ3-CD1 3.86Å; W168-L172 WeakPolarHBondContact O-CG 3.28Å; W168-L172 PolarHBondContact O-N 3.23Å; W168-A413 HydrophobicContact CB-CB 4.12Å; W168-V414 HydrophobicContact CB-CG2 3.86Å; W168-V414 HydrophobicContact CG-CG2 4.35Å
169	G	87.9	Confident	86.4	Confident	12 Å²	12	50.1 Å²	50.1	12%	0.124	26%	0.261	C	S	.	.	H	α-helix	trans	-68.3	-42.1	173.7	0	0	0	0	0	111.7	P166 L167 V171 L172 I173	P166-G169 CarbonylContact O-C 3.59Å; P166-G169 WeakPolarHBondContact O-CA 3.45Å; P166-G169 PolarHBondContact O-N 3.18Å; L167-G169 PolarHBondContact O-N 2.86Å; G169-V171 VanDerWaalsContact C-N 3.35Å; G169-V171 PolarHBondContact O-N 2.96Å; G169-L172 PolarHBondContact O-N 2.97Å; G169-I173 VanDerWaalsContact O-CG1 3.29Å; G169-I173 WeakPolarHBondContact O-CG1 3.35Å; G169-I173 PolarHBondContact O-N 3.05Å
170	G	88.3	Confident	86	Confident	0 Å²	0	55 Å²	55	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-58.5	-44.2	172.4	0	0	0	0	0	112.5	P166 L167 L172 I173 T174	P166-G170 PolarHBondContact O-N 3.4Å; L167-G170 CarbonylContact O-C 3.58Å; L167-G170 WeakPolarHBondContact O-CA 3.01Å; L167-G170 PolarHBondContact O-N 3.47Å; G170-L172 VanDerWaalsContact C-N 3.34Å; G170-L172 PolarHBondContact O-N 2.68Å; G170-I173 WeakPolarHBondContact O-CB 3.36Å; G170-I173 PolarHBondContact O-N 3.45Å; G170-T174 WeakPolarHBondContact O-CG2 3.44Å; G170-T174 PolarHBondContact O-N 3.32Å
171	V	88.3	Confident	85.3	Confident	2 Å²	2	52.9 Å²	52.9	1%	0.012	27%	0.271	C	S	.	.	H	α-helix	trans	-62.8	-38.1	175.2	175.4	0	0	0	0	111.7	V150 A154 L167 W168 G169 I173 T174 I406 T409 V410	V150-V171 HydrophobicContact CG1-CB 4.19Å; V150-V171 HydrophobicContact CG1-CG1 3.6Å; V150-V171 HydrophobicContact CG1-CG2 4.05Å; A154-V171 HydrophobicContact CB-CB 4.5Å; A154-V171 HydrophobicContact CB-CG2 3.6Å; L167-V171 WeakPolarHBondContact O-CG2 3.5Å; L167-V171 PolarHBondContact O-N 3.47Å; W168-V171 PolarHBondContact O-N 3.41Å; G169-V171 VanDerWaalsContact C-N 3.35Å; G169-V171 PolarHBondContact O-N 2.96Å; V171-I173 VanDerWaalsContact C-N 3.34Å; V171-T174 PolarHBondContact O-N 3.4Å; V171-T174 PolarHBondContact O-OG1 3.47Å; V171-I406 HydrophobicContact CG1-CG2 4Å; V171-T409 HydrophobicContact CG1-CG2 4.28Å; V171-T409 HydrophobicContact CG2-CG2 3.94Å; V171-V410 HydrophobicContact CB-CG2 4.24Å; V171-V410 HydrophobicContact CG1-CG2 3.34Å
172	L	88.9	Confident	84.6	Confident	76 Å²	76	52.5 Å²	52.5	40%	0.398	27%	0.267	S	S	.	.	H	α-helix	trans	-70.2	-32.4	175.6	-70.1	176.2	0	0	0	112.4	W168 G169 G170 T174 I175 V410	W168-L172 HydrophobicContact CE3-CD1 3.79Å; W168-L172 HydrophobicContact CZ3-CD1 3.86Å; W168-L172 WeakPolarHBondContact O-CG 3.28Å; W168-L172 PolarHBondContact O-N 3.23Å; G169-L172 PolarHBondContact O-N 2.97Å; G170-L172 VanDerWaalsContact C-N 3.34Å; G170-L172 PolarHBondContact O-N 2.68Å; L172-T174 PolarHBondContact O-N 2.94Å; L172-I175 HydrophobicContact CD2-CD1 3.93Å; L172-I175 VanDerWaalsContact O-CB 3.31Å; L172-I175 WeakPolarHBondContact O-CB 3.45Å; L172-I175 WeakPolarHBondContact O-CG1 2.82Å; L172-I175 PolarHBondContact O-N 2.68Å; L172-I175 VanDerWaalsContact O-N 3.13Å; L172-V410 HydrophobicContact CD2-CG2 4.38Å
173	I	89.4	Confident	84.5	Confident	62 Å²	62	56 Å²	56	32%	0.318	28%	0.275	S	S	.	.	H	α-helix	trans	-64.3	-30.1	175.8	-69.7	164.3	0	0	0	110.9	F157 I165 G169 G170 V171 I175 V176	F157-I173 HydrophobicContact CD2-CG2 4.17Å; F157-I173 HydrophobicContact CE1-CG2 4.46Å; F157-I173 HydrophobicContact CE2-CB 4.33Å; F157-I173 HydrophobicContact CE2-CG2 3.58Å; F157-I173 HydrophobicContact CZ-CG2 3.75Å; I165-I173 HydrophobicContact CD1-CD1 4.17Å; I165-I173 HydrophobicContact CG2-CD1 4.02Å; G169-I173 VanDerWaalsContact O-CG1 3.29Å; G169-I173 WeakPolarHBondContact O-CG1 3.35Å; G169-I173 PolarHBondContact O-N 3.05Å; G170-I173 WeakPolarHBondContact O-CB 3.36Å; G170-I173 PolarHBondContact O-N 3.45Å; V171-I173 VanDerWaalsContact C-N 3.34Å; I173-I175 PolarHBondContact O-N 3.16Å; I173-V176 WeakPolarHBondContact O-CA 3.32Å; I173-V176 VanDerWaalsContact O-CB 3.26Å; I173-V176 WeakPolarHBondContact O-CB 3.36Å; I173-V176 PolarHBondContact O-N 2.89Å
174	T	87.8	Confident	84.2	Confident	1 Å²	1	55.7 Å²	55.7	1%	0.006	26%	0.264	C	S	.	.	H	α-helix	trans	-63.2	-23.4	175.5	71.5	0	0	0	0	112.2	V150 T153 G170 V171 L172 V176 D177 T178	V150-T174 HydrophobicContact CG1-CG2 4.31Å; T153-T174 HydrophobicContact CG2-CG2 3.62Å; G170-T174 WeakPolarHBondContact O-CG2 3.44Å; G170-T174 PolarHBondContact O-N 3.32Å; V171-T174 PolarHBondContact O-N 3.4Å; V171-T174 PolarHBondContact O-OG1 3.47Å; L172-T174 PolarHBondContact O-N 2.94Å; T174-V176 PolarHBondContact O-N 3.45Å; T174-V176 VanDerWaalsContact O-N 3.1Å; T174-D177 WeakPolarHBondContact CA-OD2 3.23Å; T174-D177 WeakPolarHBondContact CB-OD2 2.95Å; T174-D177 PolarHBondContact O-N 3.31Å; T174-T178 PolarHBondContact O-N 3.27Å
175	I	84.9	Confident	83.5	Confident	62 Å²	62	46.1 Å²	46.1	32%	0.318	23%	0.228	S	C	.	.	H	α-helix	trans	-57	-34.8	170.7	-59.7	170	0	0	0	110.9	L172 I173 T178 F179 I406	L172-I175 HydrophobicContact CD2-CD1 3.93Å; L172-I175 VanDerWaalsContact O-CB 3.31Å; L172-I175 WeakPolarHBondContact O-CB 3.45Å; L172-I175 WeakPolarHBondContact O-CG1 2.82Å; L172-I175 PolarHBondContact O-N 2.68Å; L172-I175 VanDerWaalsContact O-N 3.13Å; I173-I175 PolarHBondContact O-N 3.16Å; I175-T178 PolarHBondContact O-N 3.01Å; I175-T178 PolarHBondContact O-OG1 2.89Å; I175-F179 HydrophobicContact CG2-CD2 4.48Å; I175-F179 HydrophobicContact CG2-CE2 3.91Å; I175-F179 WeakPolarHBondContact O-CD2 2.76Å; I175-I406 HydrophobicContact CG1-CD1 3.7Å
176	V	84.9	Confident	82.9	Confident	95 Å²	95	47.7 Å²	47.7	58%	0.576	24%	0.237	S	C	*	.	H	α-helix	trans	-69.3	-33.4	177.3	-174.3	0	0	0	0	111.9	I173 T174 T178 F179 F180	I173-V176 WeakPolarHBondContact O-CA 3.32Å; I173-V176 VanDerWaalsContact O-CB 3.26Å; I173-V176 WeakPolarHBondContact O-CB 3.36Å; I173-V176 PolarHBondContact O-N 2.89Å; T174-V176 PolarHBondContact O-N 3.45Å; T174-V176 VanDerWaalsContact O-N 3.1Å; V176-T178 VanDerWaalsContact C-N 3.26Å; V176-T178 PolarHBondContact O-N 3.22Å; V176-F179 PolarHBondContact O-N 2.99Å; V176-F180 PolarHBondContact O-N 3.31Å
177	D	81.6	Confident	82.3	Confident	12 Å²	12	50.7 Å²	50.7	6%	0.064	24%	0.243	C	C	.	.	H	α-helix	trans	-62.7	-35.1	176.9	70	36.4	0	0	0	112.1	T174 F179 F180 F181 Q370	T174-D177 WeakPolarHBondContact CA-OD2 3.23Å; T174-D177 WeakPolarHBondContact CB-OD2 2.95Å; T174-D177 PolarHBondContact O-N 3.31Å; D177-F179 VanDerWaalsContact C-N 3.28Å; D177-F179 PolarHBondContact O-N 3.35Å; D177-F180 WeakPolarHBondContact O-CB 3.08Å; D177-F180 PolarHBondContact O-N 2.92Å; D177-F180 VanDerWaalsContact O-N 3.1Å; D177-F181 WeakPolarHBondContact O-CB 3.34Å; D177-F181 PolarHBondContact O-N 3.23Å; D177-Q370 VanDerWaalsContact CB-OE1 3.26Å; D177-Q370 PolarHBondContact OD2-NE2 3.38Å; D177-Q370 VanDerWaalsContact OD2-NE2 3.07Å
178	T	77.9	Confident	82	Confident	4 Å²	4	50.5 Å²	50.5	3%	0.025	25%	0.245	C	C	.	.	H	α-helix	trans	-63.1	-37.9	177.8	71.6	0	0	0	0	111.5	T174 I175 V176 L182 R402	T174-T178 PolarHBondContact O-N 3.27Å; I175-T178 PolarHBondContact O-N 3.01Å; I175-T178 PolarHBondContact O-OG1 2.89Å; V176-T178 VanDerWaalsContact C-N 3.26Å; V176-T178 PolarHBondContact O-N 3.22Å; T178-L182 WeakPolarHBondContact O-CD1 3.44Å; T178-L182 VanDerWaalsContact O-CG 3.24Å; T178-L182 WeakPolarHBondContact O-CG 3.44Å; T178-L182 PolarHBondContact O-N 3.03Å; T178-L182 VanDerWaalsContact O-N 3.08Å; T178-R402 HydrophobicContact CG2-CB 4.16Å; T178-R402 HydrophobicContact CG2-CG 3.57Å
179	F	81	Confident	81.5	Confident	115 Å²	115	45 Å²	45	50%	0.504	23%	0.225	S	C	.	.	H	α-helix	trans	-70.5	-39.4	174.9	-69.5	-68.8	0	0	0	111.7	I175 V176 D177 F181 L182 F183	I175-F179 HydrophobicContact CG2-CD2 4.48Å; I175-F179 HydrophobicContact CG2-CE2 3.91Å; I175-F179 WeakPolarHBondContact O-CD2 2.76Å; V176-F179 PolarHBondContact O-N 2.99Å; D177-F179 VanDerWaalsContact C-N 3.28Å; D177-F179 PolarHBondContact O-N 3.35Å; F179-F181 VanDerWaalsContact C-N 3.34Å; F179-L182 PolarHBondContact O-N 3.32Å; F179-F183 PolarHBondContact O-N 3.12Å
180	F	82.5	Confident	81.3	Confident	102 Å²	102	48.5 Å²	48.5	45%	0.447	24%	0.235	S	C	.	.	H	α-helix	trans	-62.6	-42.2	175.7	180	-106.4	0	0	0	111.7	V176 D177 F183 L184 F195	V176-F180 PolarHBondContact O-N 3.31Å; D177-F180 WeakPolarHBondContact O-CB 3.08Å; D177-F180 PolarHBondContact O-N 2.92Å; D177-F180 VanDerWaalsContact O-N 3.1Å; F180-F183 WeakPolarHBondContact O-CB 3.38Å; F180-F183 PolarHBondContact O-N 3.43Å; F180-L184 HydrophobicContact CD1-CD1 3.83Å; F180-L184 HydrophobicContact CD1-CG 4.46Å; F180-L184 HydrophobicContact CE1-CD1 3.25Å; F180-L184 HydrophobicContact CE1-CG 4.03Å; F180-L184 HydrophobicContact CZ-CD1 3.67Å; F180-L184 HydrophobicContact CZ-CD2 4.41Å; F180-L184 HydrophobicContact CZ-CG 4.05Å; F180-L184 PolarHBondContact O-N 3.25Å; F180-F195 HydrophobicContact CE1-CZ 4.2Å
181	F	77.2	Confident	81.2	Confident	9 Å²	9	55.2 Å²	55.2	4%	0.039	26%	0.264	C	S	.	.	H	α-helix	trans	-59.6	-49.9	173.8	168.2	-115.6	0	0	0	112.1	D177 F179 F183 L184 D185 M374 T377 Y378	D177-F181 WeakPolarHBondContact O-CB 3.34Å; D177-F181 PolarHBondContact O-N 3.23Å; F179-F181 VanDerWaalsContact C-N 3.34Å; F181-F183 PolarHBondContact O-N 3.15Å; F181-L184 PolarHBondContact O-N 3.48Å; F181-D185 PolarHBondContact O-N 3.43Å; F181-M374 HydrophobicContact CB-CG 4.44Å; F181-M374 HydrophobicContact CD2-CB 3.76Å; F181-M374 HydrophobicContact CD2-CE 3.6Å; F181-M374 HydrophobicContact CD2-CG 3.33Å; F181-M374 HydrophobicContact CD2-SD 3.99Å; F181-M374 HydrophobicContact CE2-CB 3.59Å; F181-M374 HydrophobicContact CE2-CE 3.71Å; F181-M374 HydrophobicContact CE2-CG 3.73Å; F181-M374 HydrophobicContact CE2-SD 4.47Å; F181-M374 HydrophobicContact CG-CG 4.07Å; F181-M374 HydrophobicContact CZ-CB 4.37Å; F181-T377 HydrophobicContact CE1-CG2 4.29Å; F181-T377 WeakPolarHBondContact CE1-OG1 3.45Å; F181-T377 VanDerWaalsContact CZ-OG1 3.29Å; F181-T377 WeakPolarHBondContact CZ-OG1 3.36Å; F181-Y378 AromaticContact CE2-CE2 3.75Å; F181-Y378 HydrophobicContact CE2-CE2 3.75Å; F181-Y378 AromaticContact CE2-CZ 3.72Å; F181-Y378 VanDerWaalsContact CE2-OH 3.25Å; F181-Y378 WeakPolarHBondContact CE2-OH 3.35Å; F181-Y378 HydrophobicContact CZ-CD2 4.44Å; F181-Y378 HydrophobicContact CZ-CE1 4.11Å; F181-Y378 AromaticContact CZ-CE2 3.74Å; F181-Y378 HydrophobicContact CZ-CE2 3.74Å; F181-Y378 AromaticContact CZ-CZ 3.5Å; F181-Y378 VanDerWaalsContact CZ-CZ 3.5Å; F181-Y378 WeakPolarHBondContact CZ-OH 3.29Å
182	L	75.9	Confident	80.9	Confident	12 Å²	12	55.3 Å²	55.3	6%	0.063	27%	0.265	C	S	.	.	H	α-helix	trans	-59.9	-30.4	178.7	-72.5	164.7	0	0	0	112.2	T178 F179 N186 F395 V398	T178-L182 WeakPolarHBondContact O-CD1 3.44Å; T178-L182 VanDerWaalsContact O-CG 3.24Å; T178-L182 WeakPolarHBondContact O-CG 3.44Å; T178-L182 PolarHBondContact O-N 3.03Å; T178-L182 VanDerWaalsContact O-N 3.08Å; F179-L182 PolarHBondContact O-N 3.32Å; L182-N186 PolarHBondContact O-ND2 3.32Å; L182-F395 HydrophobicContact CB-CE1 4.1Å; L182-F395 HydrophobicContact CB-CZ 4.27Å; L182-F395 HydrophobicContact CD1-CD1 3.61Å; L182-F395 HydrophobicContact CD1-CE1 3.68Å; L182-F395 HydrophobicContact CD1-CG 4.39Å; L182-F395 HydrophobicContact CD2-CD1 4.44Å; L182-F395 HydrophobicContact CD2-CE1 4.43Å; L182-F395 HydrophobicContact CG-CD1 4.5Å; L182-F395 HydrophobicContact CG-CE1 4.29Å; L182-V398 HydrophobicContact CD1-CG1 4.4Å; L182-V398 HydrophobicContact CD2-CB 4.49Å; L182-V398 HydrophobicContact CD2-CG2 4.19Å
183	F	80.9	Confident	80.8	Confident	116 Å²	116	52.6 Å²	52.6	51%	0.509	25%	0.25	S	C	.	.	H	α-helix	trans	-70	-46.9	171.8	-177.7	-104.1	0	0	0	111.9	F179 F180 F181 D185 N186 Y187	F179-F183 PolarHBondContact O-N 3.12Å; F180-F183 WeakPolarHBondContact O-CB 3.38Å; F180-F183 PolarHBondContact O-N 3.43Å; F181-F183 PolarHBondContact O-N 3.15Å; F183-D185 PolarHBondContact O-N 3.21Å; F183-N186 PolarHBondContact O-N 2.91Å; F183-Y187 AromaticContact CD1-CE2 3.76Å; F183-Y187 HydrophobicContact CD1-CE2 3.76Å; F183-Y187 HydrophobicContact CD2-CE2 4.47Å; F183-Y187 AromaticContact CE1-CE2 3.41Å; F183-Y187 HydrophobicContact CE1-CE2 3.41Å; F183-Y187 VanDerWaalsContact CE1-CE2 3.41Å; F183-Y187 AromaticContact CE1-CZ 3.77Å; F183-Y187 WeakPolarHBondContact CE1-OH 3.02Å; F183-Y187 HydrophobicContact CE2-CE2 4.16Å; F183-Y187 HydrophobicContact CG-CE2 4.31Å; F183-Y187 AromaticContact CZ-CE2 3.65Å; F183-Y187 HydrophobicContact CZ-CE2 3.65Å; F183-Y187 AromaticContact CZ-CZ 3.77Å; F183-Y187 WeakPolarHBondContact CZ-OH 3.39Å; F183-Y187 VanDerWaalsContact O-CD2 3.29Å; F183-Y187 WeakPolarHBondContact O-CD2 3.29Å
184	L	75.8	Confident	80.8	Confident	32 Å²	32	52.8 Å²	52.8	17%	0.168	26%	0.26	C	S	.	.	H	α-helix	trans	-63	-35.4	178.5	-80.2	177.4	0	0	0	113.6	F180 F181 N186 Y187 F195	F180-L184 HydrophobicContact CD1-CD1 3.83Å; F180-L184 HydrophobicContact CD1-CG 4.46Å; F180-L184 HydrophobicContact CE1-CD1 3.25Å; F180-L184 HydrophobicContact CE1-CG 4.03Å; F180-L184 HydrophobicContact CZ-CD1 3.67Å; F180-L184 HydrophobicContact CZ-CD2 4.41Å; F180-L184 HydrophobicContact CZ-CG 4.05Å; F180-L184 PolarHBondContact O-N 3.25Å; F181-L184 PolarHBondContact O-N 3.48Å; L184-N186 PolarHBondContact O-N 3.49Å; L184-N186 VanDerWaalsContact O-N 3.09Å; L184-Y187 WeakPolarHBondContact O-CB 3.06Å; L184-Y187 PolarHBondContact O-N 2.99Å; L184-F195 HydrophobicContact CD1-CD1 4.07Å; L184-F195 HydrophobicContact CD1-CE1 3.81Å; L184-F195 HydrophobicContact CD1-CE2 4.46Å; L184-F195 HydrophobicContact CD1-CG 4.49Å; L184-F195 HydrophobicContact CD1-CZ 4.03Å
185	D	70.9	Confident	80.8	Confident	8 Å²	8	55.2 Å²	55.2	4%	0.043	27%	0.271	C	S	.	.	G	3₁₀ helix	trans	-57.4	-25.4	177.8	-169.4	51.5	0	0	0	112.5	Y35 F181 F183 Y187 Y378 R394	Y35-D185 WeakPolarHBondContact CD2-OD1 3.25Å; Y35-D185 WeakPolarHBondContact CE2-OD1 3.16Å; F181-D185 PolarHBondContact O-N 3.43Å; F183-D185 PolarHBondContact O-N 3.21Å; D185-Y187 VanDerWaalsContact C-N 3.3Å; D185-Y187 PolarHBondContact O-N 3.43Å; D185-Y378 PolarHBondContact OD1-OH 2.93Å; D185-R394 IonicContact OD2-CZ 2.89Å; D185-R394 IonicContact OD2-NH1 2.97Å; D185-R394 PolarHBondContact OD2-NH1 3.22Å
186	N	76.2	Confident	81	Confident	85 Å²	85	52.2 Å²	52.2	46%	0.455	26%	0.256	S	S	.	.	G	3₁₀ helix	trans	-77.8	-9.4	178.1	-61.3	-54.4	0	0	0	114.2	L182 F183 L184	L182-N186 PolarHBondContact O-ND2 3.32Å; F183-N186 PolarHBondContact O-N 2.91Å; L184-N186 PolarHBondContact O-N 3.49Å; L184-N186 VanDerWaalsContact O-N 3.09Å
187	Y	75.8	Confident	81.2	Confident	114 Å²	114	48.9 Å²	48.9	45%	0.447	24%	0.241	S	C	.	.	G	3₁₀ helix	trans	-89.8	1.8	-173.2	-78.9	-93.8	0	0	0	114.9	F183 L184 D185 K191	F183-Y187 AromaticContact CD1-CE2 3.76Å; F183-Y187 HydrophobicContact CD1-CE2 3.76Å; F183-Y187 HydrophobicContact CD2-CE2 4.47Å; F183-Y187 AromaticContact CE1-CE2 3.41Å; F183-Y187 HydrophobicContact CE1-CE2 3.41Å; F183-Y187 VanDerWaalsContact CE1-CE2 3.41Å; F183-Y187 AromaticContact CE1-CZ 3.77Å; F183-Y187 WeakPolarHBondContact CE1-OH 3.02Å; F183-Y187 HydrophobicContact CE2-CE2 4.16Å; F183-Y187 HydrophobicContact CG-CE2 4.31Å; F183-Y187 AromaticContact CZ-CE2 3.65Å; F183-Y187 HydrophobicContact CZ-CE2 3.65Å; F183-Y187 AromaticContact CZ-CZ 3.77Å; F183-Y187 WeakPolarHBondContact CZ-OH 3.39Å; F183-Y187 VanDerWaalsContact O-CD2 3.29Å; F183-Y187 WeakPolarHBondContact O-CD2 3.29Å; L184-Y187 WeakPolarHBondContact O-CB 3.06Å; L184-Y187 PolarHBondContact O-N 2.99Å; D185-Y187 VanDerWaalsContact C-N 3.3Å; D185-Y187 PolarHBondContact O-N 3.43Å; Y187-K191 WeakPolarHBondContact O-CD 3.3Å
188	G	78	Confident	81.8	Confident	16 Å²	16	52.9 Å²	52.9	17%	0.165	26%	0.262	C	S	.	.			trans	88.9	157.5	175.3	0	0	0	0	0	114.1	R190 K191 L192	G188-R190 PolarHBondContact O-N 3.2Å; G188-K191 PolarHBondContact O-N 3.32Å; G188-L192 PolarHBondContact O-N 3.49Å
189	L	78.3	Confident	82.5	Confident	10 Å²	10	53.3 Å²	53.3	5%	0.052	26%	0.264	C	S	.	.	H	α-helix	trans	-64.8	-40.9	-163.9	-167.9	140.8	0	0	0	113.8	Y35 I40 K191 L192 E193	Y35-L189 HydrophobicContact CD1-CD1 3.7Å; Y35-L189 HydrophobicContact CD1-CG 4.4Å; Y35-L189 HydrophobicContact CE1-CD1 3.95Å; Y35-L189 HydrophobicContact CE1-CG 4.17Å; Y35-L189 HydrophobicContact CG-CD1 4.36Å; Y35-L189 WeakPolarHBondContact O-CD1 3.31Å; I40-L189 HydrophobicContact CD1-CD2 3.46Å; I40-L189 VanDerWaalsContact CD1-CD2 3.46Å; I40-L189 HydrophobicContact CG1-CD2 4.5Å; L189-K191 PolarHBondContact O-N 2.95Å; L189-L192 PolarHBondContact O-N 3.12Å; L189-E193 HydrophobicContact CD2-CG 4.22Å; L189-E193 WeakPolarHBondContact CD2-OE1 3.36Å; L189-E193 WeakPolarHBondContact O-CG 3.5Å; L189-E193 PolarHBondContact O-N 3.3Å
190	R	83.6	Confident	83	Confident	85 Å²	85	48.2 Å²	48.2	32%	0.321	24%	0.241	S	C	.	.	H	α-helix	trans	-67.2	-37.2	-179.7	-77.6	-51.1	-161.6	169	-0.4	114.7	I40 W56 A57 T59 G188 L192 E193 A194	I40-R190 HydrophobicContact CD1-CG 4.01Å; I40-R190 VanDerWaalsContact CD1-NE 3.34Å; W56-R190 PolarHBondContact O-NH2 3.04Å; A57-R190 VanDerWaalsContact C-NH2 3.35Å; A57-R190 VanDerWaalsContact CA-NH2 3.3Å; A57-R190 PolarHBondContact O-NH2 3.23Å; T59-R190 PolarHBondContact O-NH1 3Å; G188-R190 PolarHBondContact O-N 3.2Å; R190-L192 VanDerWaalsContact C-N 3.27Å; R190-E193 WeakPolarHBondContact CD-OE2 3.36Å; R190-E193 IonicContact CZ-OE2 3.02Å; R190-E193 IonicContact NE-OE2 3.26Å; R190-E193 IonicContact NH1-OE2 2.97Å; R190-E193 PolarHBondContact NH1-OE2 2.85Å; R190-A194 PolarHBondContact O-N 3.24Å; R190-A194 VanDerWaalsContact O-N 3.12Å
191	K	85.4	Confident	83.6	Confident	142 Å²	142	47 Å²	47	62%	0.617	24%	0.242	S	C	*	.	H	α-helix	trans	-69.2	-34.2	177.9	-66.2	-173.1	-171.5	167.5	0	110.8	Y187 G188 L189 A194 F195	Y187-K191 WeakPolarHBondContact O-CD 3.3Å; G188-K191 PolarHBondContact O-N 3.32Å; L189-K191 PolarHBondContact O-N 2.95Å; K191-A194 PolarHBondContact O-N 2.61Å; K191-F195 PolarHBondContact O-N 2.99Å
192	L	82.6	Confident	84.5	Confident	4 Å²	4	49 Å²	49	2%	0.021	25%	0.253	C	S	.	.	H	α-helix	trans	-73.9	-41.1	179.5	-156.6	159.4	0	0	0	111.8	Y35 G188 L189 R190 A194 F195 F196 M374 Y378	Y35-L192 HydrophobicContact CE2-CD1 3.58Å; Y35-L192 WeakPolarHBondContact OH-CD1 3.13Å; Y35-L192 WeakPolarHBondContact OH-CD2 3.42Å; Y35-L192 VanDerWaalsContact OH-CG 3.23Å; Y35-L192 WeakPolarHBondContact OH-CG 2.93Å; G188-L192 PolarHBondContact O-N 3.49Å; L189-L192 PolarHBondContact O-N 3.12Å; R190-L192 VanDerWaalsContact C-N 3.27Å; L192-A194 VanDerWaalsContact C-N 3.27Å; L192-A194 PolarHBondContact O-N 3.3Å; L192-F195 WeakPolarHBondContact O-CB 3.29Å; L192-F195 PolarHBondContact O-N 3.47Å; L192-F195 VanDerWaalsContact O-N 3.15Å; L192-F196 HydrophobicContact CD2-CD2 3.23Å; L192-F196 HydrophobicContact CD2-CE2 2.93Å; L192-F196 HydrophobicContact CD2-CG 4.23Å; L192-F196 HydrophobicContact CD2-CZ 3.7Å; L192-F196 HydrophobicContact CG-CE2 4.43Å; L192-F196 WeakPolarHBondContact O-CD2 3.39Å; L192-F196 PolarHBondContact O-N 3.18Å; L192-M374 HydrophobicContact CD1-CE 3.88Å; L192-M374 HydrophobicContact CD2-CE 3.37Å; L192-M374 HydrophobicContact CG-CE 3.71Å; L192-Y378 WeakPolarHBondContact CD1-OH 3.35Å
193	E	86.9	Confident	85.3	Confident	18 Å²	18	48.5 Å²	48.5	8%	0.084	25%	0.25	C	S	.	.	H	α-helix	trans	-55.8	-41.1	168.3	-72.1	174.2	169.3	0	0	112.1	G60 L64 L189 R190 F196 G197 R264	G60-E193 VanDerWaalsContact CA-CD 3.41Å; G60-E193 VanDerWaalsContact CA-OE1 3.3Å; G60-E193 WeakPolarHBondContact CA-OE1 3.34Å; L64-E193 HydrophobicContact CD1-CB 4.28Å; L64-E193 HydrophobicContact CD1-CG 3.69Å; L189-E193 HydrophobicContact CD2-CG 4.22Å; L189-E193 WeakPolarHBondContact CD2-OE1 3.36Å; L189-E193 WeakPolarHBondContact O-CG 3.5Å; L189-E193 PolarHBondContact O-N 3.3Å; R190-E193 WeakPolarHBondContact CD-OE2 3.36Å; R190-E193 IonicContact CZ-OE2 3.02Å; R190-E193 IonicContact NE-OE2 3.26Å; R190-E193 IonicContact NH1-OE2 2.97Å; R190-E193 PolarHBondContact NH1-OE2 2.85Å; E193-F196 PolarHBondContact O-N 3.44Å; E193-G197 PolarHBondContact O-N 3Å; E193-R264 IonicContact OE1-CZ 3.45Å; E193-R264 IonicContact OE1-NH1 3.34Å; E193-R264 PolarHBondContact OE1-NH1 3.27Å; E193-R264 VanDerWaalsContact OE1-NH1 3.1Å; E193-R264 IonicContact OE1-NH2 3.84Å; E193-R264 PolarHBondContact OE1-NH2 2.92Å; E193-R264 IonicContact OE2-NH2 2.77Å; E193-R264 PolarHBondContact OE2-NH2 3.28Å
194	A	88.1	Confident	86	Confident	66 Å²	66	44.5 Å²	44.5	55%	0.545	24%	0.239	S	C	.	.	H	α-helix	trans	-66.8	-38.3	176.4	0	0	0	0	0	112.7	R190 K191 L192 G197 L198	R190-A194 PolarHBondContact O-N 3.24Å; R190-A194 VanDerWaalsContact O-N 3.12Å; K191-A194 PolarHBondContact O-N 2.61Å; L192-A194 VanDerWaalsContact C-N 3.27Å; L192-A194 PolarHBondContact O-N 3.3Å; A194-G197 PolarHBondContact O-N 3.09Å; A194-L198 PolarHBondContact O-N 3.19Å
195	F	89	Confident	86.9	Confident	52 Å²	52	48.8 Å²	48.8	23%	0.228	26%	0.262	C	S	.	.	H	α-helix	trans	-62.1	-42.9	174.5	177.4	-106.9	0	0	0	111.7	F180 L184 K191 L192 L198 L199 M374	F180-F195 HydrophobicContact CE1-CZ 4.2Å; L184-F195 HydrophobicContact CD1-CD1 4.07Å; L184-F195 HydrophobicContact CD1-CE1 3.81Å; L184-F195 HydrophobicContact CD1-CE2 4.46Å; L184-F195 HydrophobicContact CD1-CG 4.49Å; L184-F195 HydrophobicContact CD1-CZ 4.03Å; K191-F195 PolarHBondContact O-N 2.99Å; L192-F195 WeakPolarHBondContact O-CB 3.29Å; L192-F195 PolarHBondContact O-N 3.47Å; L192-F195 VanDerWaalsContact O-N 3.15Å; F195-L198 WeakPolarHBondContact O-CB 3.11Å; F195-L198 PolarHBondContact O-N 3.03Å; F195-L199 HydrophobicContact CD1-CD1 4.21Å; F195-L199 HydrophobicContact CE1-CD1 3.64Å; F195-L199 HydrophobicContact CE1-CG 4.27Å; F195-L199 HydrophobicContact CZ-CD1 3.99Å; F195-L199 HydrophobicContact CZ-CD2 4.32Å; F195-L199 HydrophobicContact CZ-CG 4.28Å; F195-L199 PolarHBondContact O-N 2.99Å; F195-L199 VanDerWaalsContact O-N 3.09Å; F195-M374 HydrophobicContact CD1-CE 4.18Å; F195-M374 HydrophobicContact CD1-SD 4.05Å; F195-M374 HydrophobicContact CE1-CE 4.39Å; F195-M374 HydrophobicContact CE1-SD 3.72Å
196	F	87.6	Confident	88	Confident	0 Å²	0	49.1 Å²	49.1	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-64	-41.2	173.2	-77.1	-49.8	0	0	0	113.1	L64 I67 L192 E193 L198 L199 I200 M374	L64-F196 HydrophobicContact CD1-CB 4.48Å; L64-F196 HydrophobicContact CD1-CD2 3.54Å; L64-F196 HydrophobicContact CD1-CE2 4.08Å; L64-F196 HydrophobicContact CD1-CG 4.4Å; L64-F196 HydrophobicContact CD2-CD2 4.12Å; L64-F196 HydrophobicContact CD2-CE2 3.79Å; L64-F196 HydrophobicContact CG-CD2 3.51Å; L64-F196 HydrophobicContact CG-CE2 3.54Å; L64-F196 HydrophobicContact CG-CG 4.47Å; I67-F196 HydrophobicContact CD1-CB 3.71Å; I67-F196 HydrophobicContact CD1-CD1 3.16Å; I67-F196 HydrophobicContact CD1-CD2 4.19Å; I67-F196 HydrophobicContact CD1-CE1 3.64Å; I67-F196 HydrophobicContact CD1-CG 3.45Å; I67-F196 VanDerWaalsContact CD1-CG 3.45Å; I67-F196 HydrophobicContact CD1-CZ 4.28Å; L192-F196 HydrophobicContact CD2-CD2 3.23Å; L192-F196 HydrophobicContact CD2-CE2 2.93Å; L192-F196 HydrophobicContact CD2-CG 4.23Å; L192-F196 HydrophobicContact CD2-CZ 3.7Å; L192-F196 HydrophobicContact CG-CE2 4.43Å; L192-F196 WeakPolarHBondContact O-CD2 3.39Å; L192-F196 PolarHBondContact O-N 3.18Å; E193-F196 PolarHBondContact O-N 3.44Å; F196-L198 PolarHBondContact O-N 2.66Å; F196-L199 HydrophobicContact CD1-CD1 4.38Å; F196-L199 PolarHBondContact O-N 2.73Å; F196-L199 VanDerWaalsContact O-N 3.12Å; F196-I200 WeakPolarHBondContact O-CG1 3.25Å; F196-I200 PolarHBondContact O-N 3.41Å; F196-M374 HydrophobicContact CD1-SD 4.38Å; F196-M374 HydrophobicContact CE1-CB 3.71Å; F196-M374 HydrophobicContact CE1-CE 3.83Å; F196-M374 HydrophobicContact CE1-CG 4.12Å; F196-M374 HydrophobicContact CE1-SD 3.57Å; F196-M374 VanDerWaalsContact CE1-SD 3.57Å; F196-M374 HydrophobicContact CE2-CE 4.06Å; F196-M374 HydrophobicContact CZ-CB 3.44Å; F196-M374 VanDerWaalsContact CZ-CB 3.44Å; F196-M374 HydrophobicContact CZ-CE 3.54Å; F196-M374 HydrophobicContact CZ-CG 4.2Å; F196-M374 HydrophobicContact CZ-SD 3.86Å
197	G	90.3	Very high	88.9	Confident	25 Å²	25	45.2 Å²	45.2	26%	0.258	24%	0.243	S	C	.	.	H	α-helix	trans	-56.9	-37.1	172.6	0	0	0	0	0	112.6	E193 A194 T201	E193-G197 PolarHBondContact O-N 3Å; A194-G197 PolarHBondContact O-N 3.09Å; G197-T201 WeakPolarHBondContact O-CB 3.35Å; G197-T201 PolarHBondContact O-N 3.46Å; G197-T201 PolarHBondContact O-OG1 3.2Å
198	L	93.2	Very high	89.8	Confident	96 Å²	96	40.3 Å²	40.3	50%	0.503	23%	0.227	S	C	.	.	H	α-helix	trans	-64.1	-47.2	173.2	177.1	67.8	0	0	0	111.8	A194 F195 F196 I200 T201 I202	A194-L198 PolarHBondContact O-N 3.19Å; F195-L198 WeakPolarHBondContact O-CB 3.11Å; F195-L198 PolarHBondContact O-N 3.03Å; F196-L198 PolarHBondContact O-N 2.66Å; L198-I200 PolarHBondContact O-N 3.09Å; L198-T201 WeakPolarHBondContact O-CB 3.47Å; L198-T201 PolarHBondContact O-N 2.88Å; L198-I202 HydrophobicContact CD1-CD1 4.4Å; L198-I202 HydrophobicContact CG-CD1 4.13Å; L198-I202 WeakPolarHBondContact O-CG1 3.49Å; L198-I202 PolarHBondContact O-N 3.11Å
199	L	92.7	Very high	90.6	Very high	13 Å²	13	44.9 Å²	44.9	7%	0.068	24%	0.24	C	C	.	.	H	α-helix	trans	-61.5	-43.8	178.4	-65.3	178.8	0	0	0	112.1	F195 F196 T201 I202 M203 A367	F195-L199 HydrophobicContact CD1-CD1 4.21Å; F195-L199 HydrophobicContact CE1-CD1 3.64Å; F195-L199 HydrophobicContact CE1-CG 4.27Å; F195-L199 HydrophobicContact CZ-CD1 3.99Å; F195-L199 HydrophobicContact CZ-CD2 4.32Å; F195-L199 HydrophobicContact CZ-CG 4.28Å; F195-L199 PolarHBondContact O-N 2.99Å; F195-L199 VanDerWaalsContact O-N 3.09Å; F196-L199 HydrophobicContact CD1-CD1 4.38Å; F196-L199 PolarHBondContact O-N 2.73Å; F196-L199 VanDerWaalsContact O-N 3.12Å; L199-T201 VanDerWaalsContact C-N 3.3Å; L199-T201 PolarHBondContact O-N 2.85Å; L199-I202 PolarHBondContact O-N 3.26Å; L199-M203 WeakPolarHBondContact O-CG 3.27Å; L199-M203 PolarHBondContact O-N 3.06Å; L199-A367 HydrophobicContact CD2-CB 4.11Å
200	I	92.8	Very high	91.2	Very high	7 Å²	7	44.5 Å²	44.5	4%	0.036	24%	0.238	C	C	.	.	H	α-helix	trans	-61.6	-41.1	175.1	-63.8	169.2	0	0	0	110.9	F63 I67 L70 F196 L198 I202 M203 A204 V291 I295	F63-I200 HydrophobicContact CB-CD1 4.45Å; F63-I200 HydrophobicContact CD1-CD1 4.08Å; I67-I200 HydrophobicContact CD1-CD1 4.45Å; I67-I200 HydrophobicContact CG1-CD1 3.88Å; I67-I200 HydrophobicContact CG1-CG1 4.1Å; L70-I200 HydrophobicContact CD1-CG1 4.39Å; L70-I200 HydrophobicContact CD1-CG2 4.33Å; F196-I200 WeakPolarHBondContact O-CG1 3.25Å; F196-I200 PolarHBondContact O-N 3.41Å; L198-I200 PolarHBondContact O-N 3.09Å; I200-I202 VanDerWaalsContact C-N 3.34Å; I200-I202 PolarHBondContact O-N 3.31Å; I200-M203 HydrophobicContact CB-CE 4.41Å; I200-M203 HydrophobicContact CG1-CE 4.06Å; I200-M203 PolarHBondContact O-N 3.28Å; I200-A204 WeakPolarHBondContact O-CB 3.23Å; I200-A204 PolarHBondContact O-N 2.95Å; I200-V291 HydrophobicContact CG2-CG1 3.99Å; I200-I295 HydrophobicContact CG2-CD1 4.36Å
201	T	94.6	Very high	91.7	Very high	76 Å²	76	41.8 Å²	41.8	47%	0.466	23%	0.228	S	C	.	.	H	α-helix	trans	-63.6	-41.5	177.1	-57.7	0	0	0	0	111.3	G197 L198 L199 A204 L205	G197-T201 WeakPolarHBondContact O-CB 3.35Å; G197-T201 PolarHBondContact O-N 3.46Å; G197-T201 PolarHBondContact O-OG1 3.2Å; L198-T201 WeakPolarHBondContact O-CB 3.47Å; L198-T201 PolarHBondContact O-N 2.88Å; L199-T201 VanDerWaalsContact C-N 3.3Å; L199-T201 PolarHBondContact O-N 2.85Å; T201-A204 PolarHBondContact O-N 2.83Å; T201-L205 HydrophobicContact CG2-CD1 4.04Å; T201-L205 HydrophobicContact CG2-CG 4.38Å; T201-L205 WeakPolarHBondContact O-CB 3.18Å; T201-L205 VanDerWaalsContact O-CG 3.27Å; T201-L205 WeakPolarHBondContact O-CG 3.12Å; T201-L205 PolarHBondContact O-N 2.96Å
202	I	95.2	Very high	92	Very high	53 Å²	53	39.8 Å²	39.8	27%	0.272	23%	0.228	S	C	.	.	H	α-helix	trans	-58.9	-50.9	174.9	-69.1	165.6	0	0	0	109.7	L198 L199 I200 A204 L205 T206 I363 A367	L198-I202 HydrophobicContact CD1-CD1 4.4Å; L198-I202 HydrophobicContact CG-CD1 4.13Å; L198-I202 WeakPolarHBondContact O-CG1 3.49Å; L198-I202 PolarHBondContact O-N 3.11Å; L199-I202 PolarHBondContact O-N 3.26Å; I200-I202 VanDerWaalsContact C-N 3.34Å; I200-I202 PolarHBondContact O-N 3.31Å; I202-A204 PolarHBondContact O-N 2.95Å; I202-L205 PolarHBondContact O-N 3.32Å; I202-T206 HydrophobicContact CG2-CG2 4.15Å; I202-T206 WeakPolarHBondContact O-CG2 3.32Å; I202-T206 PolarHBondContact O-N 3.23Å; I202-T206 PolarHBondContact O-OG1 3.01Å; I202-T206 VanDerWaalsContact O-OG1 3.09Å; I202-I363 HydrophobicContact CG2-CG2 3.81Å; I202-A367 HydrophobicContact CB-CB 4.33Å; I202-A367 HydrophobicContact CG2-CB 3.97Å
203	M	93.9	Very high	92.4	Very high	0 Å²	0	41.8 Å²	41.8	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-58.5	-44.7	178	-68.7	-173.7	-73.6	0	0	112.6	L70 L199 I200 L205 T206 F207 I295 A367 A368	L70-M203 HydrophobicContact CB-CE 3.92Å; L70-M203 HydrophobicContact CB-SD 4.05Å; L70-M203 HydrophobicContact CD1-CE 3.7Å; L70-M203 HydrophobicContact CG-CE 4.45Å; L199-M203 WeakPolarHBondContact O-CG 3.27Å; L199-M203 PolarHBondContact O-N 3.06Å; I200-M203 HydrophobicContact CB-CE 4.41Å; I200-M203 HydrophobicContact CG1-CE 4.06Å; I200-M203 PolarHBondContact O-N 3.28Å; M203-L205 VanDerWaalsContact C-N 3.32Å; M203-L205 PolarHBondContact O-N 3.32Å; M203-T206 WeakPolarHBondContact CA-OG1 3.46Å; M203-T206 PolarHBondContact O-N 2.86Å; M203-T206 PolarHBondContact O-OG1 2.97Å; M203-T206 VanDerWaalsContact O-OG1 3.12Å; M203-F207 HydrophobicContact CB-CD2 4.06Å; M203-F207 HydrophobicContact CB-CE2 3.96Å; M203-F207 HydrophobicContact CG-CE2 4.15Å; M203-F207 WeakPolarHBondContact O-CB 3.49Å; M203-F207 WeakPolarHBondContact O-CD2 3.19Å; M203-F207 WeakPolarHBondContact O-CG 3.46Å; M203-F207 PolarHBondContact O-N 3.24Å; M203-I295 HydrophobicContact CB-CD1 4.46Å; M203-A367 HydrophobicContact CG-CB 3.89Å; M203-A368 VanDerWaalsContact SD-CA 3.51Å; M203-A368 HydrophobicContact SD-CB 3.63Å
204	A	95.1	Very high	92.5	Very high	33 Å²	33	41.5 Å²	41.5	27%	0.273	24%	0.24	S	C	.	.	H	α-helix	trans	-61.1	-40.2	177.7	0	0	0	0	0	112.2	I200 T201 I202 G208 I295	I200-A204 WeakPolarHBondContact O-CB 3.23Å; I200-A204 PolarHBondContact O-N 2.95Å; T201-A204 PolarHBondContact O-N 2.83Å; I202-A204 PolarHBondContact O-N 2.95Å; A204-G208 VanDerWaalsContact O-CA 3.31Å; A204-G208 WeakPolarHBondContact O-CA 2.96Å; A204-G208 PolarHBondContact O-N 2.98Å; A204-I295 HydrophobicContact CB-CD1 4.07Å; A204-I295 HydrophobicContact CB-CG1 4.24Å
205	L	95.6	Very high	92.6	Very high	122 Å²	122	48.3 Å²	48.3	64%	0.639	25%	0.252	S	S	*	.	H	α-helix	trans	-72.6	-42.9	177.8	-69.7	174.7	0	0	0	112.2	T201 I202 M203 Y209	T201-L205 HydrophobicContact CG2-CD1 4.04Å; T201-L205 HydrophobicContact CG2-CG 4.38Å; T201-L205 WeakPolarHBondContact O-CB 3.18Å; T201-L205 VanDerWaalsContact O-CG 3.27Å; T201-L205 WeakPolarHBondContact O-CG 3.12Å; T201-L205 PolarHBondContact O-N 2.96Å; I202-L205 PolarHBondContact O-N 3.32Å; M203-L205 VanDerWaalsContact C-N 3.32Å; M203-L205 PolarHBondContact O-N 3.32Å; L205-Y209 VanDerWaalsContact O-CB 3.26Å; L205-Y209 WeakPolarHBondContact O-CB 3.21Å; L205-Y209 PolarHBondContact O-N 3.34Å
206	T	94.2	Very high	92.5	Very high	14 Å²	14	46 Å²	46	9%	0.086	24%	0.242	C	C	.	.	H	α-helix	trans	-68.1	-53.6	-178.8	54.4	0	0	0	0	111.1	I202 M203 G208 Y209 E210 I360 I363 G364	I202-T206 HydrophobicContact CG2-CG2 4.15Å; I202-T206 WeakPolarHBondContact O-CG2 3.32Å; I202-T206 PolarHBondContact O-N 3.23Å; I202-T206 PolarHBondContact O-OG1 3.01Å; I202-T206 VanDerWaalsContact O-OG1 3.09Å; M203-T206 WeakPolarHBondContact CA-OG1 3.46Å; M203-T206 PolarHBondContact O-N 2.86Å; M203-T206 PolarHBondContact O-OG1 2.97Å; M203-T206 VanDerWaalsContact O-OG1 3.12Å; T206-G208 VanDerWaalsContact C-N 3.33Å; T206-G208 PolarHBondContact O-N 3.41Å; T206-Y209 WeakPolarHBondContact O-CB 3.09Å; T206-Y209 PolarHBondContact O-N 3.4Å; T206-E210 PolarHBondContact O-N 3.28Å; T206-E210 VanDerWaalsContact O-N 3.13Å; T206-I360 WeakPolarHBondContact CB-O 3.49Å; T206-I360 HydrophobicContact CG2-CG2 3.9Å; T206-I360 WeakPolarHBondContact CG2-O 3.3Å; T206-I360 WeakPolarHBondContact O-CG2 3.21Å; T206-I363 HydrophobicContact CG2-CB 4.44Å; T206-I363 HydrophobicContact CG2-CG2 4.22Å; T206-G364 WeakPolarHBondContact OG1-CA 3.31Å
207	F	93.6	Very high	92.6	Very high	3 Å²	3	50.6 Å²	50.6	1%	0.013	27%	0.267	C	S	.	.	H	α-helix	trans	-72	-30.5	-179.6	-57	-43.8	0	0	0	112	I75 M203 E210 Y211 I295 V299 W361	I75-F207 HydrophobicContact CD1-CE2 3.93Å; I75-F207 HydrophobicContact CD1-CZ 3.85Å; M203-F207 HydrophobicContact CB-CD2 4.06Å; M203-F207 HydrophobicContact CB-CE2 3.96Å; M203-F207 HydrophobicContact CG-CE2 4.15Å; M203-F207 WeakPolarHBondContact O-CB 3.49Å; M203-F207 WeakPolarHBondContact O-CD2 3.19Å; M203-F207 WeakPolarHBondContact O-CG 3.46Å; M203-F207 PolarHBondContact O-N 3.24Å; F207-E210 PolarHBondContact O-N 2.86Å; F207-Y211 WeakPolarHBondContact O-CB 3.38Å; F207-Y211 PolarHBondContact O-N 2.93Å; F207-I295 HydrophobicContact CB-CG2 4.47Å; F207-I295 HydrophobicContact CD2-CG2 3.53Å; F207-I295 HydrophobicContact CE2-CG2 4.22Å; F207-I295 HydrophobicContact CG-CG2 4.42Å; F207-V299 HydrophobicContact CB-CG2 4.23Å; F207-V299 HydrophobicContact CD1-CG2 4.18Å; F207-V299 HydrophobicContact CD2-CG2 4.15Å; F207-V299 HydrophobicContact CG-CG2 3.94Å; F207-W361 AromaticContact CD1-CE3 3.88Å; F207-W361 HydrophobicContact CD1-CE3 3.88Å; F207-W361 AromaticContact CD1-CZ3 3.76Å; F207-W361 HydrophobicContact CD1-CZ3 3.76Å; F207-W361 HydrophobicContact CE1-CD2 4.36Å; F207-W361 AromaticContact CE1-CE3 3.54Å; F207-W361 HydrophobicContact CE1-CE3 3.54Å; F207-W361 HydrophobicContact CE1-CH2 4.25Å; F207-W361 AromaticContact CE1-CZ3 3.45Å; F207-W361 HydrophobicContact CE1-CZ3 3.45Å; F207-W361 VanDerWaalsContact CE1-CZ3 3.45Å; F207-W361 HydrophobicContact CZ-CZ3 4.41Å
208	G	94.6	Very high	92.7	Very high	12 Å²	12	53.7 Å²	53.7	12%	0.124	27%	0.274	C	S	.	.	H	α-helix	trans	-64.5	-38.3	170.4	0	0	0	0	0	112.9	A204 T206 Y211 V212	A204-G208 VanDerWaalsContact O-CA 3.31Å; A204-G208 WeakPolarHBondContact O-CA 2.96Å; A204-G208 PolarHBondContact O-N 2.98Å; T206-G208 VanDerWaalsContact C-N 3.33Å; T206-G208 PolarHBondContact O-N 3.41Å; G208-Y211 PolarHBondContact O-N 3.03Å; G208-V212 WeakPolarHBondContact O-CG2 3.5Å; G208-V212 PolarHBondContact O-N 3.36Å; G208-V212 VanDerWaalsContact O-N 3.09Å
209	Y	94.4	Very high	92.5	Very high	111 Å²	111	50.8 Å²	50.8	44%	0.435	27%	0.268	S	S	.	.	H	α-helix	trans	-62.9	-48.1	173.5	176.8	-90.9	0	0	0	111.4	L205 T206 Y211 V212 V213 I360	L205-Y209 VanDerWaalsContact O-CB 3.26Å; L205-Y209 WeakPolarHBondContact O-CB 3.21Å; L205-Y209 PolarHBondContact O-N 3.34Å; T206-Y209 WeakPolarHBondContact O-CB 3.09Å; T206-Y209 PolarHBondContact O-N 3.4Å; Y209-Y211 VanDerWaalsContact C-N 3.27Å; Y209-Y211 PolarHBondContact O-N 3.37Å; Y209-V212 PolarHBondContact O-N 3.02Å; Y209-V212 VanDerWaalsContact O-N 3.15Å; Y209-V213 HydrophobicContact CD1-CG2 4.05Å; Y209-V213 HydrophobicContact CD2-CG2 4.43Å; Y209-V213 HydrophobicContact CE1-CG2 3.61Å; Y209-V213 HydrophobicContact CE2-CG2 4.02Å; Y209-V213 HydrophobicContact CG-CG2 4.45Å; Y209-V213 WeakPolarHBondContact O-CG2 3.48Å; Y209-V213 PolarHBondContact O-N 2.95Å; Y209-I360 HydrophobicContact CD1-CD1 3.45Å; Y209-I360 VanDerWaalsContact CD1-CD1 3.45Å; Y209-I360 HydrophobicContact CD1-CG2 4.21Å; Y209-I360 HydrophobicContact CE1-CD1 3.41Å; Y209-I360 VanDerWaalsContact CE1-CD1 3.41Å; Y209-I360 HydrophobicContact CG-CD1 4.14Å
210	E	91.6	Very high	92.2	Very high	3 Å²	3	51.5 Å²	51.5	1%	0.014	28%	0.275	C	S	.	.	H	α-helix	trans	-56.4	-42.5	176.1	-66.6	-57.1	144.5	0	0	111.6	T206 F207 V212 V213 A214 V302 L349 A357 I360	T206-E210 PolarHBondContact O-N 3.28Å; T206-E210 VanDerWaalsContact O-N 3.13Å; F207-E210 PolarHBondContact O-N 2.86Å; E210-V212 PolarHBondContact O-N 3.42Å; E210-V213 PolarHBondContact O-N 3.37Å; E210-A214 WeakPolarHBondContact O-CB 3.49Å; E210-A214 PolarHBondContact O-N 3.36Å; E210-V302 HydrophobicContact CB-CG1 4.48Å; E210-V302 HydrophobicContact CB-CG2 4.17Å; E210-L349 HydrophobicContact CG-CD1 4.41Å; E210-A357 WeakPolarHBondContact OE1-CA 3.49Å; E210-A357 WeakPolarHBondContact OE1-CB 3.36Å; E210-A357 VanDerWaalsContact OE1-O 3.1Å; E210-I360 HydrophobicContact CG-CG2 4.46Å
211	Y	94	Very high	92.1	Very high	28 Å²	28	51.4 Å²	51.4	11%	0.11	28%	0.275	C	S	.	.	H	α-helix	trans	-60.1	-45.2	176.2	-179	-95.4	0	0	0	113.1	F207 G208 Y209 V213 R215 P216 Q218 L221 F298 A301 V302	F207-Y211 WeakPolarHBondContact O-CB 3.38Å; F207-Y211 PolarHBondContact O-N 2.93Å; G208-Y211 PolarHBondContact O-N 3.03Å; Y209-Y211 VanDerWaalsContact C-N 3.27Å; Y209-Y211 PolarHBondContact O-N 3.37Å; Y211-V213 VanDerWaalsContact C-N 3.34Å; Y211-R215 PolarHBondContact O-N 2.87Å; Y211-P216 HydrophobicContact CD2-CG 3.73Å; Y211-P216 HydrophobicContact CE2-CG 3.31Å; Y211-P216 VanDerWaalsContact O-CD 3.28Å; Y211-P216 WeakPolarHBondContact O-CD 3.37Å; Y211-Q218 VanDerWaalsContact OH-CD 3.26Å; Y211-Q218 PolarHBondContact OH-NE2 3.48Å; Y211-Q218 PolarHBondContact OH-OE1 3.36Å; Y211-L221 HydrophobicContact CE2-CD1 3.91Å; Y211-F298 AromaticContact CD1-CD1 3.85Å; Y211-F298 HydrophobicContact CD1-CD1 3.85Å; Y211-F298 AromaticContact CD1-CE1 3.82Å; Y211-F298 HydrophobicContact CD1-CE1 3.82Å; Y211-F298 HydrophobicContact CD2-CB 4.16Å; Y211-F298 AromaticContact CD2-CD1 3.51Å; Y211-F298 HydrophobicContact CD2-CD1 3.51Å; Y211-F298 HydrophobicContact CD2-CE1 4.26Å; Y211-F298 HydrophobicContact CD2-CG 4.12Å; Y211-F298 HydrophobicContact CE1-CD1 4.19Å; Y211-F298 AromaticContact CE1-CE1 3.97Å; Y211-F298 HydrophobicContact CE1-CE1 3.97Å; Y211-F298 AromaticContact CE2-CD1 3.86Å; Y211-F298 HydrophobicContact CE2-CD1 3.86Å; Y211-F298 HydrophobicContact CE2-CE1 4.37Å; Y211-F298 HydrophobicContact CG-CB 4.28Å; Y211-F298 AromaticContact CG-CD1 3.48Å; Y211-F298 HydrophobicContact CG-CD1 3.48Å; Y211-F298 VanDerWaalsContact CG-CD1 3.48Å; Y211-F298 AromaticContact CG-CE1 3.96Å; Y211-F298 HydrophobicContact CG-CE1 3.96Å; Y211-F298 AromaticContact CG-CG 3.96Å; Y211-F298 HydrophobicContact CG-CG 3.96Å; Y211-A301 HydrophobicContact CD2-CB 4.06Å; Y211-A301 HydrophobicContact CE2-CB 3.77Å; Y211-V302 VanDerWaalsContact CA-CG2 3.44Å; Y211-V302 HydrophobicContact CD2-CG2 4.44Å
212	V	93	Very high	91.9	Very high	100 Å²	100	52.4 Å²	52.4	61%	0.606	28%	0.277	S	S	*	.	H	α-helix	trans	-67.2	-36.9	179.5	172.3	0	0	0	0	111.6	G208 Y209 E210 R215	G208-V212 WeakPolarHBondContact O-CG2 3.5Å; G208-V212 PolarHBondContact O-N 3.36Å; G208-V212 VanDerWaalsContact O-N 3.09Å; Y209-V212 PolarHBondContact O-N 3.02Å; Y209-V212 VanDerWaalsContact O-N 3.15Å; E210-V212 PolarHBondContact O-N 3.42Å; V212-R215 WeakPolarHBondContact O-CG 3.23Å
213	V	90.9	Very high	91.5	Very high	45 Å²	45	58.4 Å²	58.4	27%	0.273	30%	0.296	S	S	.	.	H	α-helix	trans	-74	-41.4	179.1	175.1	0	0	0	0	111.5	Y209 E210 Y211 R215 F353	Y209-V213 HydrophobicContact CD1-CG2 4.05Å; Y209-V213 HydrophobicContact CD2-CG2 4.43Å; Y209-V213 HydrophobicContact CE1-CG2 3.61Å; Y209-V213 HydrophobicContact CE2-CG2 4.02Å; Y209-V213 HydrophobicContact CG-CG2 4.45Å; Y209-V213 WeakPolarHBondContact O-CG2 3.48Å; Y209-V213 PolarHBondContact O-N 2.95Å; E210-V213 PolarHBondContact O-N 3.37Å; Y211-V213 VanDerWaalsContact C-N 3.34Å; V213-R215 VanDerWaalsContact C-N 3.25Å; V213-R215 PolarHBondContact O-N 3.02Å; V213-F353 HydrophobicContact CG1-CB 3.81Å; V213-F353 HydrophobicContact CG1-CD1 3.53Å; V213-F353 HydrophobicContact CG1-CD2 4.43Å; V213-F353 HydrophobicContact CG1-CE1 4.2Å; V213-F353 HydrophobicContact CG1-CG 3.67Å
214	A	88.1	Confident	91.2	Very high	12 Å²	12	59 Å²	59	10%	0.099	30%	0.302	C	S	.	.	H	α-helix	trans	-67.4	-24.4	178.9	0	0	0	0	0	113.5	E210 V302 F353	E210-A214 WeakPolarHBondContact O-CB 3.49Å; E210-A214 PolarHBondContact O-N 3.36Å; A214-V302 HydrophobicContact CB-CB 4.48Å; A214-V302 HydrophobicContact CB-CG1 4.24Å; A214-V302 HydrophobicContact CB-CG2 4.04Å; A214-F353 HydrophobicContact CB-CE2 4.13Å; A214-F353 HydrophobicContact CB-CZ 3.85Å
215	R	89.3	Confident	90.9	Very high	210 Å²	210	58.4 Å²	58.4	79%	0.792	30%	0.295	S	S	*	.			trans	46.2	58.2	179.1	-61.7	-175.2	179.6	178	1	113.1	Y211 V212 V213	Y211-R215 PolarHBondContact O-N 2.87Å; V212-R215 WeakPolarHBondContact O-CG 3.23Å; V213-R215 VanDerWaalsContact C-N 3.25Å; V213-R215 PolarHBondContact O-N 3.02Å
216	P	88.4	Confident	90.5	Very high	4 Å²	4	58.6 Å²	58.6	3%	0.026	30%	0.295	C	S	.	.			trans	-62.3	151	177.7	26.5	-32.3	0	0	0	111.1	F87 Y211 Q218 A301 Q305	F87-P216 HydrophobicContact CE1-CB 4.36Å; F87-P216 HydrophobicContact CZ-CB 4.09Å; Y211-P216 HydrophobicContact CD2-CG 3.73Å; Y211-P216 HydrophobicContact CE2-CG 3.31Å; Y211-P216 VanDerWaalsContact O-CD 3.28Å; Y211-P216 WeakPolarHBondContact O-CD 3.37Å; P216-Q218 PolarHBondContact O-N 2.88Å; P216-Q218 PolarHBondContact O-NE2 3.29Å; P216-A301 HydrophobicContact CB-CB 4.43Å; P216-A301 HydrophobicContact CG-CB 4.24Å; P216-Q305 HydrophobicContact CB-CB 4.22Å
217	D	90.2	Very high	90.1	Very high	95 Å²	95	63 Å²	63	51%	0.508	32%	0.318	S	S	.	.			trans	-64.5	107.9	177	177.3	17.9	0	0	0	110.8	G219 A220 L221	D217-G219 PolarHBondContact O-N 2.96Å; D217-G219 PolarHBondContact OD1-N 3.04Å; D217-A220 HydrophobicContact CB-CB 4.14Å; D217-A220 PolarHBondContact O-N 3.45Å; D217-A220 WeakPolarHBondContact OD2-CB 3.3Å; D217-A220 PolarHBondContact OD2-N 3.4Å; D217-L221 WeakPolarHBondContact O-CB 3.05Å; D217-L221 PolarHBondContact O-N 3.08Å
218	Q	90.5	Very high	89.5	Confident	90 Å²	90	67 Å²	67	42%	0.421	34%	0.344	S	S	.	.	H	α-helix	trans	-62.5	-31.3	-178.9	-56.6	-58.1	-59.6	0	0	112	Y211 P216 L222	Y211-Q218 VanDerWaalsContact OH-CD 3.26Å; Y211-Q218 PolarHBondContact OH-NE2 3.48Å; Y211-Q218 PolarHBondContact OH-OE1 3.36Å; P216-Q218 PolarHBondContact O-N 2.88Å; P216-Q218 PolarHBondContact O-NE2 3.29Å; Q218-L222 WeakPolarHBondContact O-CB 3.39Å; Q218-L222 WeakPolarHBondContact O-CG 3.12Å; Q218-L222 PolarHBondContact O-N 3.36Å
219	G	89	Confident	88.6	Confident	35 Å²	35	70 Å²	70	36%	0.361	36%	0.364	S	S	.	.	H	α-helix	trans	-68.2	-46.9	179	0	0	0	0	0	111.8	D217 R223	D217-G219 PolarHBondContact O-N 2.96Å; D217-G219 PolarHBondContact OD1-N 3.04Å; G219-R223 VanDerWaalsContact O-CG 3.31Å; G219-R223 WeakPolarHBondContact O-CG 3.26Å; G219-R223 PolarHBondContact O-N 3.48Å
220	A	87.5	Confident	87.7	Confident	28 Å²	28	66.4 Å²	66.4	23%	0.231	35%	0.354	C	S	.	.	H	α-helix	trans	-66.1	-39.2	174.6	0	0	0	0	0	112.3	F87 D217 R223 G224	F87-A220 HydrophobicContact CD2-CB 3.67Å; F87-A220 HydrophobicContact CE2-CB 4.04Å; D217-A220 HydrophobicContact CB-CB 4.14Å; D217-A220 PolarHBondContact O-N 3.45Å; D217-A220 WeakPolarHBondContact OD2-CB 3.3Å; D217-A220 PolarHBondContact OD2-N 3.4Å; A220-R223 PolarHBondContact O-N 3.45Å; A220-G224 PolarHBondContact O-N 3.16Å
221	L	90	Very high	86.8	Confident	6 Å²	6	70.5 Å²	70.5	3%	0.031	38%	0.381	C	S	.	.	H	α-helix	trans	-62	-49.8	178.5	-175.3	147.8	0	0	0	112.2	L90 Y211 D217 R223 G224 L225 L297 A301	L90-L221 HydrophobicContact CD1-CB 4.49Å; L90-L221 HydrophobicContact CD1-CG 3.92Å; Y211-L221 HydrophobicContact CE2-CD1 3.91Å; D217-L221 WeakPolarHBondContact O-CB 3.05Å; D217-L221 PolarHBondContact O-N 3.08Å; L221-R223 VanDerWaalsContact C-N 3.3Å; L221-R223 PolarHBondContact O-N 2.93Å; L221-G224 PolarHBondContact O-N 2.92Å; L221-L225 WeakPolarHBondContact O-CB 3.35Å; L221-L225 PolarHBondContact O-N 2.79Å; L221-L297 HydrophobicContact CD1-CD1 4.37Å; L221-L297 HydrophobicContact CD2-CD1 4.23Å; L221-L297 HydrophobicContact CD2-CD2 4.48Å; L221-L297 HydrophobicContact CG-CD1 4.35Å; L221-A301 HydrophobicContact CD1-CB 3.53Å
222	L	90.4	Very high	85.6	Confident	96 Å²	96	72.6 Å²	72.6	50%	0.503	41%	0.411	S	S	.	.	H	α-helix	trans	-63.5	-36.6	178	-75.9	168.7	0	0	0	112.3	Q218 L225 L226	Q218-L222 WeakPolarHBondContact O-CB 3.39Å; Q218-L222 WeakPolarHBondContact O-CG 3.12Å; Q218-L222 PolarHBondContact O-N 3.36Å; L222-L225 PolarHBondContact O-N 2.93Å; L222-L226 PolarHBondContact O-N 3.35Å; L222-L226 VanDerWaalsContact O-N 3.13Å
223	R	88.3	Confident	84.9	Confident	179 Å²	179	70.4 Å²	70.4	68%	0.675	40%	0.399	S	S	*	.	H	α-helix	trans	-65.2	-47.3	173.9	-74.4	176.4	-172.8	166.2	4	111.3	G219 A220 L221 L225 L226 L227	G219-R223 VanDerWaalsContact O-CG 3.31Å; G219-R223 WeakPolarHBondContact O-CG 3.26Å; G219-R223 PolarHBondContact O-N 3.48Å; A220-R223 PolarHBondContact O-N 3.45Å; L221-R223 VanDerWaalsContact C-N 3.3Å; L221-R223 PolarHBondContact O-N 2.93Å; R223-L225 PolarHBondContact O-N 2.88Å; R223-L226 PolarHBondContact O-N 3.27Å; R223-L227 HydrophobicContact CB-CD1 4.21Å; R223-L227 HydrophobicContact CG-CD1 4.29Å; R223-L227 VanDerWaalsContact O-CB 3.3Å; R223-L227 WeakPolarHBondContact O-CB 3.5Å; R223-L227 PolarHBondContact O-N 3.41Å
224	G	86.4	Confident	84.4	Confident	12 Å²	12	70 Å²	70	12%	0.124	41%	0.405	C	S	.	.	H	α-helix	trans	-63.2	-29.2	178.3	0	0	0	0	0	113.5	F87 W91 A220 L221	F87-G224 VanDerWaalsContact O-CA 3.29Å; F87-G224 WeakPolarHBondContact O-CA 3.44Å; W91-G224 PolarHBondContact N-O 3.49Å; A220-G224 PolarHBondContact O-N 3.16Å; L221-G224 PolarHBondContact O-N 2.92Å
225	L	89.4	Confident	84	Confident	22 Å²	22	73.9 Å²	73.9	12%	0.115	42%	0.421	C	S	.	.	H	α-helix	trans	-75.8	-43.1	177.8	-176.5	63.3	0	0	0	113.3	L90 L94 L221 L222 R223 F293	L90-L225 HydrophobicContact CB-CB 4.46Å; L90-L225 HydrophobicContact CB-CD1 4.5Å; L94-L225 HydrophobicContact CB-CD1 3.72Å; L94-L225 HydrophobicContact CD2-CD1 3.9Å; L94-L225 HydrophobicContact CD2-CG 4.2Å; L94-L225 HydrophobicContact CG-CD1 4.25Å; L221-L225 WeakPolarHBondContact O-CB 3.35Å; L221-L225 PolarHBondContact O-N 2.79Å; L222-L225 PolarHBondContact O-N 2.93Å; R223-L225 PolarHBondContact O-N 2.88Å; L225-F293 HydrophobicContact CD1-CE2 4.31Å; L225-F293 HydrophobicContact CD1-CZ 3.66Å
226	L	87.8	Confident	83.6	Confident	125 Å²	125	67.3 Å²	67.3	65%	0.654	41%	0.405	S	S	*	.	H	α-helix	trans	-96.1	-27	-171.4	-64.9	176.9	0	0	0	114.2	L222 R223 P228	L222-L226 PolarHBondContact O-N 3.35Å; L222-L226 VanDerWaalsContact O-N 3.13Å; R223-L226 PolarHBondContact O-N 3.27Å; L226-P228 WeakPolarHBondContact O-CD 3.27Å
227	L	85.2	Confident	83.5	Confident	106 Å²	106	68.8 Å²	68.8	56%	0.555	41%	0.411	S	S	*	.			trans	-99.9	110.2	-176.6	-69.3	157.9	0	0	0	110.1	R223 S229	R223-L227 HydrophobicContact CB-CD1 4.21Å; R223-L227 HydrophobicContact CG-CD1 4.29Å; R223-L227 VanDerWaalsContact O-CB 3.3Å; R223-L227 WeakPolarHBondContact O-CB 3.5Å; R223-L227 PolarHBondContact O-N 3.41Å; L227-S229 PolarHBondContact O-N 2.87Å
228	P	81	Confident	83.1	Confident	88 Å²	88	68.2 Å²	68.2	57%	0.571	41%	0.408	S	S	*	.			trans	-73.1	82.2	173.2	30.9	-33.8	0	0	0	109.3	W91 L226	W91-P228 HydrophobicContact CD2-CB 3.93Å; W91-P228 HydrophobicContact CE3-CB 3.96Å; W91-P228 HydrophobicContact CG-CB 4.3Å; W91-P228 HydrophobicContact CZ3-CB 4.4Å; L226-P228 WeakPolarHBondContact O-CD 3.27Å
229	S	75.4	Confident	82.7	Confident	76 Å²	76	67.3 Å²	67.3	53%	0.531	41%	0.406	S	S	.	.			trans	-144.5	124.4	176.1	-168.8	0	0	0	0	109.6	L227 P231	L227-S229 PolarHBondContact O-N 2.87Å; S229-P231 WeakPolarHBondContact O-CD 3.24Å
230	C	76.4	Confident	82.5	Confident	35 Å²	35	67.1 Å²	67.1	24%	0.236	40%	0.395	C	S	.	.			trans	-119.2	84.3	168.7	-169.4	0	0	0	0	110.7	G232 C233	C230-G232 PolarHBondContact O-N 3.44Å; C230-C233 HydrophobicContact CB-CB 3.71Å; C230-C233 WeakPolarHBondContact CB-SG 3.22Å; C230-C233 PolarHBondContact O-N 3.43Å; C230-C233 WeakPolarHBondContact SG-CB 3.34Å; C230-C233 CovalentContact SG-SG 1.99Å; C230-C233 PolarHBondContact SG-SG 3.33Å
231	P	71.3	Confident	82.4	Confident	88 Å²	88	66.5 Å²	66.5	57%	0.571	39%	0.39	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.6	120	173	25.4	-30.5	0	0	0	109.5	K88 S229	K88-P231 PolarHBondContact NZ-O 2.73Å; S229-P231 WeakPolarHBondContact O-CD 3.24Å
232	G	69	Low	82	Confident	72 Å²	72	66.9 Å²	66.9	74%	0.742	39%	0.393	S	S	*	.	T	Hydrogen-bonded Turn	trans	79.9	18.7	178.4	0	0	0	0	0	115.8	C230 G234	C230-G232 PolarHBondContact O-N 3.44Å; G232-G234 PolarHBondContact O-N 3.03Å
233	C	77.9	Confident	81.7	Confident	54 Å²	54	63 Å²	63	37%	0.365	38%	0.375	S	S	.	.			trans	-63.3	129.1	170.2	-99	0	0	0	0	110.9	C230 E237	C230-C233 HydrophobicContact CB-CB 3.71Å; C230-C233 WeakPolarHBondContact CB-SG 3.22Å; C230-C233 PolarHBondContact O-N 3.43Å; C230-C233 WeakPolarHBondContact SG-CB 3.34Å; C230-C233 CovalentContact SG-SG 1.99Å; C230-C233 PolarHBondContact SG-SG 3.33Å; C233-E237 HydrophobicContact CB-CB 4.18Å; C233-E237 WeakPolarHBondContact SG-CB 3.31Å
234	G	81	Confident	81.6	Confident	37 Å²	37	54.4 Å²	54.4	38%	0.381	34%	0.343	S	S	.	.			trans	-107.2	-159.1	170	0	0	0	0	0	112.4	G232 P236 E237 L238	G232-G234 PolarHBondContact O-N 3.03Å; G234-P236 VanDerWaalsContact C-CD 3.45Å; G234-E237 WeakPolarHBondContact CA-OE2 3.33Å; G234-E237 PolarHBondContact N-OE2 3.21Å; G234-L238 PolarHBondContact O-N 3.45Å
235	H	80	Confident	81.6	Confident	94 Å²	94	54.8 Å²	54.8	44%	0.435	34%	0.343	S	S	.	.	H	α-helix	trans	-61	-40.3	175.2	-163.4	-69	0	0	0	114.6	L238 L239 Y479	H235-L238 PolarHBondContact O-N 2.96Å; H235-L239 WeakPolarHBondContact ND1-CD1 3.26Å; H235-L239 WeakPolarHBondContact O-CG 3.45Å; H235-L239 PolarHBondContact O-N 3.33Å; H235-L239 VanDerWaalsContact O-N 3.07Å; H235-Y479 PolarHBondContact NE2-OH 3.13Å
236	P	80.3	Confident	81.2	Confident	71 Å²	71	53.8 Å²	53.8	46%	0.461	34%	0.338	S	S	.	.	H	α-helix	trans	-69.5	-38.3	-177.1	25.4	-30	0	0	0	112.2	V84 G234 L238 L239 Q240	V84-P236 HydrophobicContact CG1-CB 4.42Å; G234-P236 VanDerWaalsContact C-CD 3.45Å; P236-L238 VanDerWaalsContact C-N 3.34Å; P236-L238 PolarHBondContact O-N 2.84Å; P236-L239 PolarHBondContact O-N 3.07Å; P236-Q240 WeakPolarHBondContact O-CG 3.2Å; P236-Q240 PolarHBondContact O-N 3.4Å
237	E	85.6	Confident	81.1	Confident	35 Å²	35	48 Å²	48	16%	0.164	31%	0.308	C	S	.	.	H	α-helix	trans	-67.4	-35.3	176.2	-61.8	82.8	173.3	0	0	112	V84 A85 C233 G234 Q240 A241	V84-E237 HydrophobicContact CG1-CG 4.25Å; A85-E237 HydrophobicContact CB-CG 4.08Å; C233-E237 HydrophobicContact CB-CB 4.18Å; C233-E237 WeakPolarHBondContact SG-CB 3.31Å; G234-E237 WeakPolarHBondContact CA-OE2 3.33Å; G234-E237 PolarHBondContact N-OE2 3.21Å; E237-Q240 PolarHBondContact O-N 2.96Å; E237-A241 WeakPolarHBondContact O-CB 3.41Å; E237-A241 PolarHBondContact O-N 3.46Å
238	L	83.1	Confident	81.2	Confident	83 Å²	83	43 Å²	43	44%	0.435	28%	0.282	S	S	.	.	H	α-helix	trans	-65.1	-42.6	174.7	-178.3	66	0	0	0	111.4	G234 H235 P236 Q240 A241 V242	G234-L238 PolarHBondContact O-N 3.45Å; H235-L238 PolarHBondContact O-N 2.96Å; P236-L238 VanDerWaalsContact C-N 3.34Å; P236-L238 PolarHBondContact O-N 2.84Å; L238-Q240 VanDerWaalsContact C-N 3.31Å; L238-Q240 PolarHBondContact O-N 3.4Å; L238-A241 WeakPolarHBondContact O-CB 3.46Å; L238-A241 PolarHBondContact O-N 2.89Å; L238-V242 WeakPolarHBondContact O-CG2 3.43Å; L238-V242 PolarHBondContact O-N 2.76Å
239	L	80.9	Confident	81.5	Confident	71 Å²	71	39 Å²	39	37%	0.372	26%	0.256	S	S	.	.	H	α-helix	trans	-60	-42.8	174.9	-73.5	174.2	0	0	0	111.4	H235 P236 V242 G243 F480	H235-L239 WeakPolarHBondContact ND1-CD1 3.26Å; H235-L239 WeakPolarHBondContact O-CG 3.45Å; H235-L239 PolarHBondContact O-N 3.33Å; H235-L239 VanDerWaalsContact O-N 3.07Å; P236-L239 PolarHBondContact O-N 3.07Å; L239-V242 PolarHBondContact O-N 3.44Å; L239-G243 PolarHBondContact O-N 3.44Å; L239-F480 HydrophobicContact CD2-CE1 4.19Å
240	Q	85.6	Confident	82.2	Confident	31 Å²	31	35.5 Å²	35.5	15%	0.145	23%	0.231	C	C	.	.	H	α-helix	trans	-65.1	-40.8	176.1	-68	-61.4	-21.7	0	0	112.2	A81 V84 L89 P236 E237 L238 V242 G243 I244	A81-Q240 HydrophobicContact CB-CB 4.23Å; V84-Q240 HydrophobicContact CB-CG 4.29Å; V84-Q240 HydrophobicContact CG1-CG 4.43Å; V84-Q240 HydrophobicContact CG2-CG 4.35Å; L89-Q240 HydrophobicContact CD1-CB 3.79Å; P236-Q240 WeakPolarHBondContact O-CG 3.2Å; P236-Q240 PolarHBondContact O-N 3.4Å; E237-Q240 PolarHBondContact O-N 2.96Å; L238-Q240 VanDerWaalsContact C-N 3.31Å; L238-Q240 PolarHBondContact O-N 3.4Å; Q240-V242 VanDerWaalsContact C-N 3.29Å; Q240-V242 PolarHBondContact O-N 3.47Å; Q240-G243 PolarHBondContact O-N 2.95Å; Q240-I244 WeakPolarHBondContact O-CG1 3.48Å; Q240-I244 PolarHBondContact O-N 2.9Å
241	A	85.8	Confident	82.8	Confident	15 Å²	15	33.9 Å²	33.9	12%	0.124	22%	0.22	C	C	.	.	H	α-helix	trans	-59.4	-41.2	174.6	0	0	0	0	0	112.3	L89 V92 E237 L238 V245	L89-A241 HydrophobicContact CD2-CB 3.8Å; V92-A241 HydrophobicContact CG1-CB 4.26Å; V92-A241 HydrophobicContact CG2-CB 4.28Å; E237-A241 WeakPolarHBondContact O-CB 3.41Å; E237-A241 PolarHBondContact O-N 3.46Å; L238-A241 WeakPolarHBondContact O-CB 3.46Å; L238-A241 PolarHBondContact O-N 2.89Å; A241-V245 WeakPolarHBondContact O-CG2 3.4Å; A241-V245 PolarHBondContact O-N 3.31Å
242	V	82	Confident	83.7	Confident	15 Å²	15	29.7 Å²	29.7	9%	0.091	19%	0.193	C	C	.	.	H	α-helix	trans	-72.3	-37.5	177.1	178	0	0	0	0	111.4	L238 L239 Q240 V245 G246 I476 F480	L238-V242 WeakPolarHBondContact O-CG2 3.43Å; L238-V242 PolarHBondContact O-N 2.76Å; L239-V242 PolarHBondContact O-N 3.44Å; Q240-V242 VanDerWaalsContact C-N 3.29Å; Q240-V242 PolarHBondContact O-N 3.47Å; V242-V245 PolarHBondContact O-N 2.96Å; V242-G246 PolarHBondContact O-N 3.15Å; V242-I476 HydrophobicContact CG1-CG2 3.47Å; V242-I476 VanDerWaalsContact CG1-CG2 3.47Å; V242-F480 HydrophobicContact CB-CE2 4.29Å; V242-F480 HydrophobicContact CB-CZ 4.27Å; V242-F480 HydrophobicContact CG1-CD2 4.16Å; V242-F480 HydrophobicContact CG1-CE2 3.12Å; V242-F480 HydrophobicContact CG1-CZ 3.49Å; V242-F480 VanDerWaalsContact CG1-CZ 3.49Å
243	G	82.6	Confident	84.8	Confident	13 Å²	13	26.2 Å²	26.2	13%	0.134	16%	0.157	C	C	.	.	H	α-helix	trans	-55.3	-48.4	171.5	0	0	0	0	0	112.2	S77 L239 Q240 V245 G246 A247	S77-G243 VanDerWaalsContact OG-C 3.31Å; L239-G243 PolarHBondContact O-N 3.44Å; Q240-G243 PolarHBondContact O-N 2.95Å; G243-V245 VanDerWaalsContact C-N 3.32Å; G243-V245 PolarHBondContact O-N 2.97Å; G243-G246 PolarHBondContact O-N 3.47Å; G243-A247 WeakPolarHBondContact O-CB 3.25Å; G243-A247 PolarHBondContact O-N 3.37Å
244	I	87.5	Confident	85.5	Confident	0 Å²	0	23.7 Å²	23.7	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-55	-46.6	175.3	-68.4	163.2	0	0	0	111.1	S77 A81 L89 V92 L93 A96 Q240 G246 A247 I248 M300	S77-I244 PolarHBondContact OG-N 2.92Å; A81-I244 HydrophobicContact CB-CD1 3.57Å; A81-I244 HydrophobicContact CB-CG1 3.95Å; L89-I244 HydrophobicContact CB-CD1 3.92Å; L89-I244 HydrophobicContact CD1-CD1 4.19Å; V92-I244 HydrophobicContact CG1-CB 4.43Å; V92-I244 HydrophobicContact CG1-CG2 4.3Å; L93-I244 HydrophobicContact CB-CG2 4.46Å; L93-I244 HydrophobicContact CD1-CG2 4.17Å; A96-I244 HydrophobicContact CB-CG2 4.24Å; Q240-I244 WeakPolarHBondContact O-CG1 3.48Å; Q240-I244 PolarHBondContact O-N 2.9Å; I244-G246 PolarHBondContact O-N 3.09Å; I244-A247 PolarHBondContact O-N 2.97Å; I244-I248 HydrophobicContact CG2-CD1 3.69Å; I244-I248 HydrophobicContact CG2-CG1 4.39Å; I244-I248 VanDerWaalsContact O-CB 3.31Å; I244-I248 WeakPolarHBondContact O-CB 3.4Å; I244-I248 VanDerWaalsContact O-CG1 3.32Å; I244-I248 WeakPolarHBondContact O-CG1 3.44Å; I244-I248 PolarHBondContact O-N 3.1Å; I244-M300 HydrophobicContact CD1-CE 3.75Å; I244-M300 HydrophobicContact CG1-CE 4.17Å
245	V	85.8	Confident	86.1	Confident	20 Å²	20	22 Å²	22	12%	0.121	12%	0.122	C	C	.	.	H	α-helix	trans	-63.9	-42.9	-179.2	174.9	0	0	0	0	111.2	V92 A96 A241 V242 G243 I249 I476	V92-V245 HydrophobicContact CG1-CG2 4.13Å; A96-V245 HydrophobicContact CB-CG2 4.17Å; A241-V245 WeakPolarHBondContact O-CG2 3.4Å; A241-V245 PolarHBondContact O-N 3.31Å; V242-V245 PolarHBondContact O-N 2.96Å; G243-V245 VanDerWaalsContact C-N 3.32Å; G243-V245 PolarHBondContact O-N 2.97Å; V245-I249 HydrophobicContact CG1-CD1 4.05Å; V245-I249 WeakPolarHBondContact O-CG1 3.35Å; V245-I249 PolarHBondContact O-N 3.33Å; V245-I476 HydrophobicContact CG1-CD1 4.36Å
246	G	82.2	Confident	86.7	Confident	0 Å²	0	17.7 Å²	17.7	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-67.3	-40.4	178.1	0	0	0	0	0	113.4	V242 G243 I244	V242-G246 PolarHBondContact O-N 3.15Å; G243-G246 PolarHBondContact O-N 3.47Å; I244-G246 PolarHBondContact O-N 3.09Å
247	A	84.5	Confident	87.3	Confident	4 Å²	4	14.4 Å²	14.4	3%	0.033	8%	0.08	C	C	.	.	H	α-helix	trans	-69.9	-38.7	178.8	0	0	0	0	0	112.2	N74 G243 I244	N74-A247 HydrophobicContact CB-CB 4.44Å; G243-A247 WeakPolarHBondContact O-CB 3.25Å; G243-A247 PolarHBondContact O-N 3.37Å; I244-A247 PolarHBondContact O-N 2.97Å
248	I	87.6	Confident	87.8	Confident	0 Å²	0	12.7 Å²	12.7	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-72.7	-46.4	178.7	-75.1	179.9	0	0	0	111.8	F69 L93 A96 I244 M250	F69-I248 HydrophobicContact CD1-CB 4.47Å; F69-I248 HydrophobicContact CD1-CG2 3.75Å; F69-I248 HydrophobicContact CE1-CB 4.49Å; F69-I248 HydrophobicContact CE1-CG2 3.45Å; F69-I248 VanDerWaalsContact CE1-CG2 3.45Å; F69-I248 WeakPolarHBondContact CE1-O 3.46Å; F69-I248 WeakPolarHBondContact CZ-O 3.39Å; L93-I248 HydrophobicContact CD1-CD1 3.6Å; L93-I248 HydrophobicContact CG-CD1 4.46Å; A96-I248 HydrophobicContact CB-CB 4.26Å; A96-I248 HydrophobicContact CB-CD1 3.63Å; A96-I248 HydrophobicContact CB-CG1 4.5Å; A96-I248 HydrophobicContact CB-CG2 4.15Å; A96-I248 WeakPolarHBondContact O-CG2 3.49Å; I244-I248 HydrophobicContact CG2-CD1 3.69Å; I244-I248 HydrophobicContact CG2-CG1 4.39Å; I244-I248 VanDerWaalsContact O-CB 3.31Å; I244-I248 WeakPolarHBondContact O-CB 3.4Å; I244-I248 VanDerWaalsContact O-CG1 3.32Å; I244-I248 WeakPolarHBondContact O-CG1 3.44Å; I244-I248 PolarHBondContact O-N 3.1Å; I248-M250 VanDerWaalsContact C-N 3.35Å; I248-M250 PolarHBondContact O-N 3.33Å; I248-M250 VanDerWaalsContact O-N 3.15Å
249	I	87.4	Confident	88.2	Confident	5 Å²	5	8.8 Å²	8.8	3%	0.026	5%	0.052	C	C	.	.	S	Bend	trans	-93.3	75.8	-175.2	-47.7	174	0	0	0	108.1	L99 V245 I254 L436 V440	L99-I249 HydrophobicContact CB-CD1 4.18Å; L99-I249 HydrophobicContact CD2-CD1 3.5Å; L99-I249 HydrophobicContact CG-CD1 3.55Å; V245-I249 HydrophobicContact CG1-CD1 4.05Å; V245-I249 WeakPolarHBondContact O-CG1 3.35Å; V245-I249 PolarHBondContact O-N 3.33Å; I249-I254 HydrophobicContact CG2-CD1 4.44Å; I249-L436 HydrophobicContact CB-CD1 3.94Å; I249-L436 HydrophobicContact CB-CD2 4.38Å; I249-L436 HydrophobicContact CG2-CD1 3.61Å; I249-L436 WeakPolarHBondContact O-CD1 3.32Å; I249-V440 HydrophobicContact CG2-CG2 4.38Å
250	M	88.9	Confident	88.6	Confident	3 Å²	3	5.6 Å²	5.6	2%	0.015	4%	0.036	C	C	.	.			trans	-77.6	129.1	-175.1	-160.1	158.3	50.8	0	0	112.1	A68 I248 H252 N253	A68-M250 HydrophobicContact CB-CE 3.29Å; A68-M250 WeakPolarHBondContact O-CE 2.95Å; I248-M250 VanDerWaalsContact C-N 3.35Å; I248-M250 PolarHBondContact O-N 3.33Å; I248-M250 VanDerWaalsContact O-N 3.15Å; M250-H252 WeakPolarHBondContact CE-CE1 3.44Å; M250-H252 WeakPolarHBondContact CE-NE2 3.34Å; M250-H252 VanDerWaalsContact CG-CE1 3.46Å; M250-H252 WeakPolarHBondContact CG-CE1 3.47Å; M250-H252 PolarHBondContact O-N 3.4Å; M250-H252 PolarHBondContact SD-CE1 3.43Å; M250-N253 HydrophobicContact CB-CB 4.21Å; M250-N253 WeakPolarHBondContact O-CB 3.5Å; M250-N253 PolarHBondContact O-N 3Å
251	P	89	Confident	88.8	Confident	0 Å²	0	4.2 Å²	4.2	0%	0	3%	0.029	C	C	.	.	H	α-helix	trans	-60.1	-47.9	-170.7	-20.4	27.7	0	0	0	113.2	I138 A141 N253 I254 Y255 L435 A439	I138-P251 HydrophobicContact CD1-CB 4.2Å; A141-P251 HydrophobicContact CB-CB 4.42Å; A141-P251 HydrophobicContact CB-CG 4.33Å; P251-N253 PolarHBondContact O-N 3Å; P251-I254 WeakPolarHBondContact O-CB 3.49Å; P251-I254 PolarHBondContact O-N 3.31Å; P251-Y255 WeakPolarHBondContact O-CD2 3.35Å; P251-L435 HydrophobicContact CG-CB 4.23Å; P251-A439 VanDerWaalsContact CA-CB 3.49Å; P251-A439 HydrophobicContact CB-CB 3.59Å; P251-A439 VanDerWaalsContact O-CB 3.27Å; P251-A439 WeakPolarHBondContact O-CB 3.5Å
252	H	90.7	Very high	89	Confident	0 Å²	0	4.7 Å²	4.7	0%	0	3%	0.028	C	C	.	.	H	α-helix	trans	-67.4	-24.1	-176.6	70.6	-107.5	0	0	0	112.5	I138 I142 S145 M250 I254 Y255 L256 A379	I138-H252 HydrophobicContact CG2-CB 4.46Å; I142-H252 HydrophobicContact CD1-CB 4.16Å; I142-H252 HydrophobicContact CG1-CB 3.49Å; I142-H252 VanDerWaalsContact CG1-CB 3.49Å; S145-H252 PolarHBondContact OG-CE1 3.27Å; M250-H252 WeakPolarHBondContact CE-CE1 3.44Å; M250-H252 WeakPolarHBondContact CE-NE2 3.34Å; M250-H252 VanDerWaalsContact CG-CE1 3.46Å; M250-H252 WeakPolarHBondContact CG-CE1 3.47Å; M250-H252 PolarHBondContact O-N 3.4Å; M250-H252 PolarHBondContact SD-CE1 3.43Å; H252-I254 VanDerWaalsContact C-N 3.31Å; H252-I254 PolarHBondContact O-N 2.94Å; H252-Y255 PolarHBondContact O-N 3.18Å; H252-L256 WeakPolarHBondContact O-CB 3.34Å; H252-L256 PolarHBondContact O-N 2.99Å; H252-A379 HydrophobicContact CB-CB 4.11Å
253	N	91.9	Very high	89.1	Confident	0 Å²	0	4.1 Å²	4.1	0%	0	3%	0.025	C	C	.	.	H	α-helix	trans	-70.6	-29.1	179.4	-162.7	21.3	0	0	0	112.1	M65 A68 F69 Q104 M250 P251 L256 H257	M65-N253 WeakPolarHBondContact CG-OD1 3.31Å; M65-N253 PolarHBondContact O-ND2 3.38Å; M65-N253 PolarHBondContact O-OD1 2.96Å; A68-N253 HydrophobicContact CB-CB 3.92Å; A68-N253 VanDerWaalsContact CB-ND2 3.25Å; A68-N253 WeakPolarHBondContact CB-ND2 3.18Å; F69-N253 VanDerWaalsContact CE2-ND2 3.26Å; F69-N253 WeakPolarHBondContact CE2-ND2 3.44Å; Q104-N253 PolarHBondContact NE2-ND2 3.31Å; M250-N253 HydrophobicContact CB-CB 4.21Å; M250-N253 WeakPolarHBondContact O-CB 3.5Å; M250-N253 PolarHBondContact O-N 3Å; P251-N253 PolarHBondContact O-N 3Å; N253-L256 PolarHBondContact O-N 3.31Å; N253-H257 WeakPolarHBondContact O-CB 3.44Å; N253-H257 PolarHBondContact O-N 3.4Å
254	I	93.7	Very high	89.3	Confident	0 Å²	0	3.6 Å²	3.6	0%	0	2%	0.019	C	C	.	.	H	α-helix	trans	-64.2	-43.5	172.7	-62.1	177.9	0	0	0	110.2	C103 A107 L118 I249 P251 H252 S258 A439 V440 I443	C103-I254 HydrophobicContact CB-CD1 4.32Å; A107-I254 HydrophobicContact CB-CG2 3.97Å; A107-I254 WeakPolarHBondContact CB-O 3.4Å; L118-I254 HydrophobicContact CD2-CG2 3.85Å; I249-I254 HydrophobicContact CG2-CD1 4.44Å; P251-I254 WeakPolarHBondContact O-CB 3.49Å; P251-I254 PolarHBondContact O-N 3.31Å; H252-I254 VanDerWaalsContact C-N 3.31Å; H252-I254 PolarHBondContact O-N 2.94Å; I254-S258 PolarHBondContact O-N 3.39Å; I254-A439 HydrophobicContact CB-CB 4.38Å; I254-A439 HydrophobicContact CD1-CB 3.98Å; I254-V440 HydrophobicContact CD1-CG2 3.74Å; I254-I443 HydrophobicContact CG2-CB 4.1Å; I254-I443 HydrophobicContact CG2-CG1 4.28Å; I254-I443 HydrophobicContact CG2-CG2 4.03Å
255	Y	93.4	Very high	89	Confident	3 Å²	3	8.4 Å²	8.4	1%	0.012	4%	0.042	C	C	.	.	H	α-helix	trans	-65.2	-47.7	175.5	-71.1	-88.3	0	0	0	111	L118 I138 P251 H252 H257 S258 A259 V383 F387 F438 A439	L118-Y255 HydrophobicContact CB-CD1 3.74Å; L118-Y255 HydrophobicContact CB-CE1 3.97Å; L118-Y255 HydrophobicContact CD2-CD1 3.77Å; L118-Y255 HydrophobicContact CD2-CD2 4.33Å; L118-Y255 HydrophobicContact CD2-CE1 3.55Å; L118-Y255 HydrophobicContact CD2-CE2 4.14Å; L118-Y255 HydrophobicContact CD2-CG 4.15Å; L118-Y255 HydrophobicContact CG-CD1 3.77Å; L118-Y255 HydrophobicContact CG-CE1 3.48Å; L118-Y255 VanDerWaalsContact CG-CE1 3.48Å; I138-Y255 HydrophobicContact CD1-CD2 4.3Å; I138-Y255 HydrophobicContact CD1-CE2 3.52Å; I138-Y255 HydrophobicContact CG1-CD2 4.38Å; I138-Y255 HydrophobicContact CG1-CE2 3.66Å; I138-Y255 HydrophobicContact CG2-CD2 4.06Å; I138-Y255 HydrophobicContact CG2-CE2 4.19Å; P251-Y255 WeakPolarHBondContact O-CD2 3.35Å; H252-Y255 PolarHBondContact O-N 3.18Å; Y255-H257 PolarHBondContact O-N 3.01Å; Y255-S258 PolarHBondContact O-N 3.23Å; Y255-S258 PolarHBondContact O-OG 3.13Å; Y255-A259 PolarHBondContact O-N 3.12Å; Y255-V383 HydrophobicContact CD1-CG2 4.36Å; Y255-V383 HydrophobicContact CG-CG2 4.04Å; Y255-F387 AromaticContact CD1-CE2 3.99Å; Y255-F387 HydrophobicContact CD1-CE2 3.99Å; Y255-F387 AromaticContact CE1-CE2 3.4Å; Y255-F387 HydrophobicContact CE1-CE2 3.4Å; Y255-F387 VanDerWaalsContact CE1-CE2 3.4Å; Y255-F387 AromaticContact CE1-CZ 3.64Å; Y255-F387 HydrophobicContact CE1-CZ 3.64Å; Y255-F387 AromaticContact CZ-CE2 3.98Å; Y255-F387 AromaticContact CZ-CZ 3.94Å; Y255-F438 PolarHBondContact OH-O 3.03Å; Y255-F438 VanDerWaalsContact OH-O 3.12Å; Y255-A439 HydrophobicContact CD2-CB 4.21Å; Y255-A439 HydrophobicContact CE2-CB 3.63Å
256	L	92.2	Very high	88.8	Confident	3 Å²	3	8.5 Å²	8.5	2%	0.016	4%	0.041	C	C	.	.	H	α-helix	trans	-57	-50.9	179.7	178.3	61.2	0	0	0	112.1	H252 N253 S258 A259 L260 T375 A379 F382	H252-L256 WeakPolarHBondContact O-CB 3.34Å; H252-L256 PolarHBondContact O-N 2.99Å; N253-L256 PolarHBondContact O-N 3.31Å; L256-S258 VanDerWaalsContact C-N 3.31Å; L256-S258 PolarHBondContact O-N 2.92Å; L256-A259 WeakPolarHBondContact O-CA 3.21Å; L256-A259 WeakPolarHBondContact O-CB 3.33Å; L256-A259 PolarHBondContact O-N 2.94Å; L256-L260 HydrophobicContact CD1-CD1 4Å; L256-L260 HydrophobicContact CD1-CD2 4.2Å; L256-L260 HydrophobicContact CD1-CG 3.86Å; L256-L260 HydrophobicContact CD2-CD1 4.24Å; L256-L260 HydrophobicContact CG-CD1 3.73Å; L256-L260 HydrophobicContact CG-CG 4.05Å; L256-L260 WeakPolarHBondContact O-CG 3.31Å; L256-L260 PolarHBondContact O-N 3.41Å; L256-T375 HydrophobicContact CD2-CG2 3.25Å; L256-A379 HydrophobicContact CB-CB 4.17Å; L256-F382 HydrophobicContact CD1-CD2 3.76Å; L256-F382 HydrophobicContact CD1-CE2 3.83Å
257	H	93.9	Very high	88.9	Confident	1 Å²	1	11.7 Å²	11.7	1%	0.005	6%	0.058	C	C	.	.	H	α-helix	trans	-64.2	-36.9	-177.3	-168.9	-164.4	0	0	0	112.4	M65 Q104 A107 N253 Y255 A259 L260 V261	M65-H257 HydrophobicContact CB-CB 4.17Å; M65-H257 HydrophobicContact CG-CB 3.74Å; Q104-H257 PolarHBondContact O-ND1 3.5Å; Q104-H257 PolarHBondContact OE1-ND1 3.19Å; A107-H257 HydrophobicContact CB-CB 4.5Å; N253-H257 WeakPolarHBondContact O-CB 3.44Å; N253-H257 PolarHBondContact O-N 3.4Å; Y255-H257 PolarHBondContact O-N 3.01Å; H257-A259 PolarHBondContact O-N 2.93Å; H257-L260 PolarHBondContact O-N 3.15Å; H257-V261 PolarHBondContact O-N 3.19Å
258	S	94.3	Very high	88.8	Confident	0 Å²	0	16.4 Å²	16.4	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-61.4	-28	174	77.8	0	0	0	0	113	A107 L118 I254 Y255 L256 V261	A107-S258 WeakPolarHBondContact O-CB 3.37Å; L118-S258 WeakPolarHBondContact CB-OG 3.47Å; L118-S258 PolarHBondContact N-OG 3.48Å; I254-S258 PolarHBondContact O-N 3.39Å; Y255-S258 PolarHBondContact O-N 3.23Å; Y255-S258 PolarHBondContact O-OG 3.13Å; L256-S258 VanDerWaalsContact C-N 3.31Å; L256-S258 PolarHBondContact O-N 2.92Å; S258-V261 VanDerWaalsContact O-CG2 3.31Å; S258-V261 WeakPolarHBondContact O-CG2 3.43Å
259	A	91.5	Very high	88.6	Confident	0 Å²	0	20.7 Å²	20.7	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-85.6	-41.1	175.6	0	0	0	0	0	112.7	D117 Y255 L256 H257 V261 K262 F382	D117-A259 HydrophobicContact CB-CB 3.85Å; Y255-A259 PolarHBondContact O-N 3.12Å; L256-A259 WeakPolarHBondContact O-CA 3.21Å; L256-A259 WeakPolarHBondContact O-CB 3.33Å; L256-A259 PolarHBondContact O-N 2.94Å; H257-A259 PolarHBondContact O-N 2.93Å; A259-V261 VanDerWaalsContact C-N 3.27Å; A259-V261 PolarHBondContact O-N 3.41Å; A259-K262 WeakPolarHBondContact O-CB 3.26Å; A259-K262 PolarHBondContact O-N 3.06Å; A259-F382 HydrophobicContact CB-CB 3.85Å; A259-F382 HydrophobicContact CB-CD1 3.59Å; A259-F382 HydrophobicContact CB-CD2 3.44Å; A259-F382 VanDerWaalsContact CB-CD2 3.44Å; A259-F382 HydrophobicContact CB-CE1 3.95Å; A259-F382 HydrophobicContact CB-CE2 3.8Å; A259-F382 HydrophobicContact CB-CG 3.32Å; A259-F382 HydrophobicContact CB-CZ 4.04Å
260	L	90	Very high	88.5	Confident	5 Å²	5	26.8 Å²	26.8	3%	0.026	13%	0.133	C	C	.	.	H	α-helix	trans	-61.6	-33.7	-177.5	-71.5	175.2	0	0	0	112.9	P61 L64 L256 H257 K262 S263 F382	P61-L260 HydrophobicContact CB-CB 3.89Å; L64-L260 HydrophobicContact CB-CD1 3.71Å; L64-L260 HydrophobicContact CD2-CD1 4.29Å; L64-L260 HydrophobicContact CD2-CD2 3.99Å; L256-L260 HydrophobicContact CD1-CD1 4Å; L256-L260 HydrophobicContact CD1-CD2 4.2Å; L256-L260 HydrophobicContact CD1-CG 3.86Å; L256-L260 HydrophobicContact CD2-CD1 4.24Å; L256-L260 HydrophobicContact CG-CD1 3.73Å; L256-L260 HydrophobicContact CG-CG 4.05Å; L256-L260 WeakPolarHBondContact O-CG 3.31Å; L256-L260 PolarHBondContact O-N 3.41Å; H257-L260 PolarHBondContact O-N 3.15Å; L260-K262 PolarHBondContact O-N 3.38Å; L260-S263 VanDerWaalsContact O-CB 3.27Å; L260-S263 WeakPolarHBondContact O-CB 3.34Å; L260-S263 PolarHBondContact O-N 2.88Å; L260-S263 VanDerWaalsContact O-N 3.1Å; L260-S263 PolarHBondContact O-OG 3.12Å; L260-F382 HydrophobicContact CD2-CE2 4.47Å
261	V	90.9	Very high	88.3	Confident	1 Å²	1	33.4 Å²	33.4	1%	0.006	16%	0.158	C	C	.	.	G	3₁₀ helix	trans	-64.8	-19.5	175.7	-62.5	0	0	0	0	113.1	A108 V112 H257 S258 A259 S263 R264 F281	A108-V261 HydrophobicContact CB-CG1 3.93Å; V112-V261 HydrophobicContact CG2-CB 4.12Å; V112-V261 HydrophobicContact CG2-CG2 4.17Å; H257-V261 PolarHBondContact O-N 3.19Å; S258-V261 VanDerWaalsContact O-CG2 3.31Å; S258-V261 WeakPolarHBondContact O-CG2 3.43Å; A259-V261 VanDerWaalsContact C-N 3.27Å; A259-V261 PolarHBondContact O-N 3.41Å; V261-S263 PolarHBondContact O-N 2.84Å; V261-R264 PolarHBondContact O-N 3.3Å; V261-F281 HydrophobicContact CB-CD2 4.46Å; V261-F281 HydrophobicContact CB-CE1 4.22Å; V261-F281 HydrophobicContact CB-CE2 3.95Å; V261-F281 HydrophobicContact CB-CZ 3.81Å; V261-F281 HydrophobicContact CG1-CD1 3.92Å; V261-F281 HydrophobicContact CG1-CD2 4.23Å; V261-F281 HydrophobicContact CG1-CE1 3.85Å; V261-F281 HydrophobicContact CG1-CE2 4.13Å; V261-F281 HydrophobicContact CG1-CG 4.11Å; V261-F281 HydrophobicContact CG1-CZ 3.94Å
262	K	88.4	Confident	88.2	Confident	26 Å²	26	37.9 Å²	37.9	11%	0.113	19%	0.185	C	C	.	.	G	3₁₀ helix	trans	-69.8	-14.9	174.5	-61.9	164.2	63.2	174.9	0	112.8	L36 G115 D117 E120 A259 L260 R264	L36-K262 HydrophobicContact CD2-CB 4.14Å; G115-K262 WeakPolarHBondContact O-CE 3.31Å; D117-K262 HydrophobicContact CB-CD 4.14Å; D117-K262 IonicContact OD2-NZ 2.64Å; D117-K262 PolarHBondContact OD2-NZ 3.06Å; E120-K262 IonicContact OE1-NZ 3.4Å; E120-K262 PolarHBondContact OE1-NZ 3.46Å; E120-K262 IonicContact OE2-NZ 3.54Å; E120-K262 PolarHBondContact OE2-NZ 3.25Å; A259-K262 WeakPolarHBondContact O-CB 3.26Å; A259-K262 PolarHBondContact O-N 3.06Å; L260-K262 PolarHBondContact O-N 3.38Å; K262-R264 PolarHBondContact O-N 3.26Å
263	S	84.9	Confident	87.9	Confident	3 Å²	3	39.5 Å²	39.5	2%	0.021	19%	0.193	C	C	.	.	G	3₁₀ helix	trans	-68.6	-16.5	178.1	66.4	0	0	0	0	113.8	K39 I40 L260 V261	K39-S263 WeakPolarHBondContact CA-O 3.49Å; I40-S263 PolarHBondContact N-O 2.64Å; L260-S263 VanDerWaalsContact O-CB 3.27Å; L260-S263 WeakPolarHBondContact O-CB 3.34Å; L260-S263 PolarHBondContact O-N 2.88Å; L260-S263 VanDerWaalsContact O-N 3.1Å; L260-S263 PolarHBondContact O-OG 3.12Å; V261-S263 PolarHBondContact O-N 2.84Å
264	R	86.4	Confident	87.7	Confident	2 Å²	2	39.9 Å²	39.9	1%	0.008	20%	0.196	C	C	.	.	B	Isolated β-bridge	trans	-97.4	133.6	177.7	-57.5	-54	-169.7	-101	12	110.2	I40 A57 F58 T59 E193 V261 K262 I266 F281	I40-R264 VanDerWaalsContact CD1-CZ 3.43Å; A57-R264 PolarHBondContact O-NE 3.16Å; F58-R264 HydrophobicContact CD1-CB 4.47Å; F58-R264 HydrophobicContact CD1-CG 4.24Å; F58-R264 HydrophobicContact CE1-CB 4.44Å; F58-R264 PolarHBondContact O-NE 3.47Å; T59-R264 PolarHBondContact O-NH2 3.09Å; E193-R264 IonicContact OE1-CZ 3.45Å; E193-R264 IonicContact OE1-NH1 3.34Å; E193-R264 PolarHBondContact OE1-NH1 3.27Å; E193-R264 VanDerWaalsContact OE1-NH1 3.1Å; E193-R264 IonicContact OE1-NH2 3.84Å; E193-R264 PolarHBondContact OE1-NH2 2.92Å; E193-R264 IonicContact OE2-NH2 2.77Å; E193-R264 PolarHBondContact OE2-NH2 3.28Å; V261-R264 PolarHBondContact O-N 3.3Å; K262-R264 PolarHBondContact O-N 3.26Å; R264-I266 PolarHBondContact O-N 2.98Å; R264-F281 HydrophobicContact CB-CZ 4.13Å; R264-F281 HydrophobicContact CG-CE1 4.29Å; R264-F281 HydrophobicContact CG-CZ 3.81Å
265	E	80.8	Confident	87.5	Confident	101 Å²	101	48.9 Å²	48.9	47%	0.472	23%	0.229	S	C	.	.			trans	-74.2	106.2	178.1	-93.2	173.1	-171.5	0	0	111.2	K39 I40 I42	K39-E265 HydrophobicContact CB-CG 3.56Å; K39-E265 HydrophobicContact CD-CG 3.52Å; K39-E265 HydrophobicContact CG-CG 4.2Å; I40-E265 PolarHBondContact O-N 2.89Å; I42-E265 WeakPolarHBondContact CD1-O 3.49Å
266	I	83.3	Confident	87.3	Confident	22 Å²	22	50.3 Å²	50.3	11%	0.113	24%	0.236	C	C	.	.			trans	-119.3	125.6	178.8	-58.9	161.5	0	0	0	108.2	I42 V112 R264 R268 D273 A277 F281	I42-I266 HydrophobicContact CD1-CG1 4.12Å; V112-I266 HydrophobicContact CG1-CD1 4.14Å; V112-I266 HydrophobicContact CG2-CD1 4.26Å; R264-I266 PolarHBondContact O-N 2.98Å; I266-R268 PolarHBondContact O-N 3.25Å; I266-D273 HydrophobicContact CG2-CB 4.38Å; I266-A277 HydrophobicContact CD1-CB 3.63Å; I266-A277 HydrophobicContact CG1-CB 4.16Å; I266-A277 HydrophobicContact CG2-CB 4.37Å; I266-F281 HydrophobicContact CD1-CE2 3.95Å
267	D	82.6	Confident	87.1	Confident	67 Å²	67	50.2 Å²	50.2	36%	0.358	24%	0.236	S	C	.	.			trans	-74.8	104.8	171.8	180	6.2	0	0	0	109.8	A269 R270	D267-A269 VanDerWaalsContact C-N 3.27Å; D267-A269 PolarHBondContact O-N 2.86Å; D267-A269 WeakPolarHBondContact OD1-CB 3.29Å; D267-A269 PolarHBondContact OD1-N 3.09Å; D267-R270 PolarHBondContact O-N 3Å; D267-R270 WeakPolarHBondContact OD2-CG 3.09Å; D267-R270 IonicContact OD2-CZ 3.68Å; D267-R270 IonicContact OD2-NE 2.86Å; D267-R270 PolarHBondContact OD2-NE 3.37Å; D267-R270 IonicContact OD2-NH2 3.86Å
268	R	83.4	Confident	87	Confident	103 Å²	103	51.2 Å²	51.2	39%	0.389	24%	0.241	S	C	.	.	T	Hydrogen-bonded Turn	trans	-78.4	-10.6	-177.4	-58.6	179.7	-169.8	117.9	1.9	113	G115 I266 R270 I274	G115-R268 VanDerWaalsContact CA-NE 3.26Å; I266-R268 PolarHBondContact O-N 3.25Å; R268-R270 VanDerWaalsContact C-N 3.3Å; R268-I274 HydrophobicContact CB-CD1 4.39Å
269	A	82.6	Confident	86.9	Confident	89 Å²	89	55.1 Å²	55.1	74%	0.736	26%	0.26	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73	-29.4	172.1	0	0	0	0	0	111.1	D267	D267-A269 VanDerWaalsContact C-N 3.27Å; D267-A269 PolarHBondContact O-N 2.86Å; D267-A269 WeakPolarHBondContact OD1-CB 3.29Å; D267-A269 PolarHBondContact OD1-N 3.09Å
270	R	85.2	Confident	86.9	Confident	133 Å²	133	55.1 Å²	55.1	50%	0.502	26%	0.26	S	S	.	.			trans	-94.8	109.7	179.5	-69.1	-172.1	-63.1	169.3	12.1	111.3	D267 R268 V272 D273 I274	D267-R270 PolarHBondContact O-N 3Å; D267-R270 WeakPolarHBondContact OD2-CG 3.09Å; D267-R270 IonicContact OD2-CZ 3.68Å; D267-R270 IonicContact OD2-NE 2.86Å; D267-R270 PolarHBondContact OD2-NE 3.37Å; D267-R270 IonicContact OD2-NH2 3.86Å; R268-R270 VanDerWaalsContact C-N 3.3Å; R270-V272 PolarHBondContact O-N 2.77Å; R270-D273 HydrophobicContact CB-CB 4.36Å; R270-D273 IonicContact CZ-OD2 3.12Å; R270-D273 IonicContact NE-OD2 3.11Å; R270-D273 PolarHBondContact NE-OD2 3.04Å; R270-D273 VanDerWaalsContact NE-OD2 3.11Å; R270-D273 IonicContact NH2-OD2 2.68Å; R270-D273 PolarHBondContact NH2-OD2 3.17Å; R270-D273 PolarHBondContact O-N 2.91Å; R270-D273 VanDerWaalsContact O-N 3.15Å; R270-I274 PolarHBondContact O-N 2.79Å
271	R	85.8	Confident	87	Confident	143 Å²	143	55 Å²	55	54%	0.54	26%	0.26	S	S	.	.	H	α-helix	trans	-61	-29.2	-179.8	-59.6	-177.7	-175.2	-179.6	-1.9	114	D273 R275 E455	R271-D273 VanDerWaalsContact C-N 3.34Å; R271-R275 PolarHBondContact O-N 3.47Å; R271-R275 VanDerWaalsContact O-N 3.15Å; R271-E455 IonicContact CZ-OE1 3.85Å; R271-E455 IonicContact CZ-OE2 2.61Å; R271-E455 IonicContact NE-OE2 3.86Å; R271-E455 IonicContact NH1-OE1 2.83Å; R271-E455 PolarHBondContact NH1-OE1 3.28Å; R271-E455 IonicContact NH1-OE2 2.73Å; R271-E455 PolarHBondContact NH1-OE2 3.2Å; R271-E455 IonicContact NH2-OE1 2.79Å
272	V	85.8	Confident	87.1	Confident	93 Å²	93	57.8 Å²	57.8	56%	0.564	27%	0.274	S	S	*	.	H	α-helix	trans	-64.4	-42.7	178.1	-179.3	0	0	0	0	110.3	R270 I274 R275 E276	R270-V272 PolarHBondContact O-N 2.77Å; V272-I274 PolarHBondContact O-N 2.91Å; V272-R275 PolarHBondContact O-N 3.35Å; V272-E276 WeakPolarHBondContact O-CB 3.43Å; V272-E276 PolarHBondContact O-N 3.5Å
273	D	85.3	Confident	87.4	Confident	34 Å²	34	59 Å²	59	18%	0.182	28%	0.282	C	S	.	.	H	α-helix	trans	-66.5	-39	-179.1	-61.7	6.7	0	0	0	111.3	I266 R270 R271 E276 A277	I266-D273 HydrophobicContact CG2-CB 4.38Å; R270-D273 HydrophobicContact CB-CB 4.36Å; R270-D273 IonicContact CZ-OD2 3.12Å; R270-D273 IonicContact NE-OD2 3.11Å; R270-D273 PolarHBondContact NE-OD2 3.04Å; R270-D273 VanDerWaalsContact NE-OD2 3.11Å; R270-D273 IonicContact NH2-OD2 2.68Å; R270-D273 PolarHBondContact NH2-OD2 3.17Å; R270-D273 PolarHBondContact O-N 2.91Å; R270-D273 VanDerWaalsContact O-N 3.15Å; R271-D273 VanDerWaalsContact C-N 3.34Å; D273-E276 PolarHBondContact O-N 2.89Å; D273-A277 VanDerWaalsContact O-CB 3.26Å; D273-A277 WeakPolarHBondContact O-CB 3.32Å; D273-A277 PolarHBondContact O-N 3.32Å
274	I	88.3	Confident	87.8	Confident	9 Å²	9	59 Å²	59	5%	0.046	28%	0.281	C	S	.	.	H	α-helix	trans	-62.2	-44.4	174	-64	174.1	0	0	0	111	V112 V113 R268 R270 V272 N278 F456	V112-I274 HydrophobicContact CG1-CG2 4.19Å; V113-I274 HydrophobicContact CG2-CG2 3.89Å; R268-I274 HydrophobicContact CB-CD1 4.39Å; R270-I274 PolarHBondContact O-N 2.79Å; V272-I274 PolarHBondContact O-N 2.91Å; I274-N278 WeakPolarHBondContact O-CB 3.4Å; I274-N278 VanDerWaalsContact O-CG 3.27Å; I274-N278 PolarHBondContact O-N 3.37Å; I274-N278 PolarHBondContact O-ND2 2.94Å; I274-N278 VanDerWaalsContact O-ND2 3.09Å; I274-F456 HydrophobicContact CB-CE2 4.11Å; I274-F456 HydrophobicContact CB-CZ 3.86Å; I274-F456 HydrophobicContact CD1-CE2 4.18Å; I274-F456 HydrophobicContact CG2-CD1 4.35Å; I274-F456 HydrophobicContact CG2-CD2 4.05Å; I274-F456 HydrophobicContact CG2-CE1 3.92Å; I274-F456 HydrophobicContact CG2-CE2 3.59Å; I274-F456 HydrophobicContact CG2-CG 4.4Å; I274-F456 HydrophobicContact CG2-CZ 3.52Å
275	R	88.6	Confident	88.1	Confident	188 Å²	188	59 Å²	59	71%	0.709	28%	0.281	S	S	*	.	H	α-helix	trans	-66.6	-41.2	178.6	-175.7	176.3	-79.6	170.9	-3	111.2	R271 V272 M279 F456	R271-R275 PolarHBondContact O-N 3.47Å; R271-R275 VanDerWaalsContact O-N 3.15Å; V272-R275 PolarHBondContact O-N 3.35Å; R275-M279 PolarHBondContact O-N 3.39Å; R275-M279 VanDerWaalsContact O-N 3.16Å; R275-F456 HydrophobicContact CB-CE1 4.24Å
276	E	88.9	Confident	88.8	Confident	33 Å²	33	55.5 Å²	55.5	15%	0.154	27%	0.27	C	S	.	.	H	α-helix	trans	-64.6	-46.8	177	-175.6	172.4	-162.9	0	0	111.2	K54 V272 D273 N278 M279 Y280	K54-E276 WeakPolarHBondContact CD-OE1 3.32Å; K54-E276 IonicContact NZ-OE1 2.77Å; K54-E276 PolarHBondContact NZ-OE1 2.94Å; K54-E276 IonicContact NZ-OE2 3.22Å; K54-E276 PolarHBondContact NZ-OE2 2.97Å; V272-E276 WeakPolarHBondContact O-CB 3.43Å; V272-E276 PolarHBondContact O-N 3.5Å; D273-E276 PolarHBondContact O-N 2.89Å; E276-N278 PolarHBondContact O-N 2.95Å; E276-M279 WeakPolarHBondContact O-CB 3.17Å; E276-M279 PolarHBondContact O-N 2.86Å; E276-M279 VanDerWaalsContact O-N 3.16Å; E276-Y280 HydrophobicContact CG-CD2 3.72Å; E276-Y280 HydrophobicContact CG-CE2 3.38Å; E276-Y280 VanDerWaalsContact O-CD2 3.26Å; E276-Y280 WeakPolarHBondContact O-CD2 3.31Å; E276-Y280 PolarHBondContact O-N 3.12Å; E276-Y280 WeakPolarHBondContact OE1-CE2 3.47Å
277	A	89.4	Confident	89.4	Confident	1 Å²	1	58.2 Å²	58.2	1%	0.008	28%	0.284	C	S	.	.	H	α-helix	trans	-60.6	-45.1	176.7	0	0	0	0	0	112.1	F58 V112 I266 D273 M279 Y280 F281	F58-A277 HydrophobicContact CE1-CB 4.02Å; F58-A277 HydrophobicContact CZ-CB 4.21Å; V112-A277 HydrophobicContact CG1-CB 3.99Å; I266-A277 HydrophobicContact CD1-CB 3.63Å; I266-A277 HydrophobicContact CG1-CB 4.16Å; I266-A277 HydrophobicContact CG2-CB 4.37Å; D273-A277 VanDerWaalsContact O-CB 3.26Å; D273-A277 WeakPolarHBondContact O-CB 3.32Å; D273-A277 PolarHBondContact O-N 3.32Å; A277-M279 PolarHBondContact O-N 3Å; A277-Y280 PolarHBondContact O-N 3.3Å; A277-F281 HydrophobicContact CB-CD2 4.39Å; A277-F281 HydrophobicContact CB-CE2 4.4Å; A277-F281 VanDerWaalsContact O-CD2 3.23Å; A277-F281 WeakPolarHBondContact O-CD2 3.38Å; A277-F281 PolarHBondContact O-N 3.32Å
278	N	91.1	Very high	89.9	Confident	23 Å²	23	55 Å²	55	12%	0.123	27%	0.267	C	S	.	.	H	α-helix	trans	-60	-33.8	176.1	-78.8	-36	0	0	0	112.8	I274 E276 L282	I274-N278 WeakPolarHBondContact O-CB 3.4Å; I274-N278 VanDerWaalsContact O-CG 3.27Å; I274-N278 PolarHBondContact O-N 3.37Å; I274-N278 PolarHBondContact O-ND2 2.94Å; I274-N278 VanDerWaalsContact O-ND2 3.09Å; E276-N278 PolarHBondContact O-N 2.95Å; N278-L282 VanDerWaalsContact O-CB 3.32Å; N278-L282 WeakPolarHBondContact O-CB 3.39Å; N278-L282 PolarHBondContact O-N 3.21Å
279	M	91	Very high	90.5	Very high	81 Å²	81	50.2 Å²	50.2	40%	0.399	25%	0.249	S	C	.	.	H	α-helix	trans	-70	-48.1	175.2	-176.6	-165.7	72	0	0	111.2	F50 R275 E276 A277 L282 I283	F50-M279 HydrophobicContact CD2-CE 4.36Å; R275-M279 PolarHBondContact O-N 3.39Å; R275-M279 VanDerWaalsContact O-N 3.16Å; E276-M279 WeakPolarHBondContact O-CB 3.17Å; E276-M279 PolarHBondContact O-N 2.86Å; E276-M279 VanDerWaalsContact O-N 3.16Å; A277-M279 PolarHBondContact O-N 3Å; M279-L282 PolarHBondContact O-N 2.75Å; M279-I283 HydrophobicContact CG-CD1 4.04Å; M279-I283 WeakPolarHBondContact O-CG1 3.45Å; M279-I283 PolarHBondContact O-N 3.23Å
280	Y	91.7	Very high	91.1	Very high	0 Å²	0	49.1 Å²	49.1	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-65.2	-43.7	-179.7	-76.2	-65.3	0	0	0	112.6	F50 S51 K54 L55 F58 E276 A277 L282 I283 E284	F50-Y280 AromaticContact CD2-CE1 3.89Å; F50-Y280 HydrophobicContact CD2-CE1 3.89Å; F50-Y280 HydrophobicContact CE2-CD1 4.44Å; F50-Y280 AromaticContact CE2-CE1 3.9Å; F50-Y280 HydrophobicContact CE2-CE1 3.9Å; S51-Y280 PolarHBondContact N-OH 3.2Å; S51-Y280 VanDerWaalsContact N-OH 3.14Å; K54-Y280 HydrophobicContact CB-CE1 4.27Å; K54-Y280 HydrophobicContact CB-CE2 4.1Å; K54-Y280 HydrophobicContact CD-CE2 4.16Å; L55-Y280 HydrophobicContact CB-CD1 4.14Å; L55-Y280 HydrophobicContact CB-CE1 4.17Å; L55-Y280 HydrophobicContact CD1-CD1 3.82Å; F58-Y280 AromaticContact CD2-CD2 3.81Å; F58-Y280 HydrophobicContact CD2-CD2 3.81Å; F58-Y280 AromaticContact CD2-CG 3.85Å; F58-Y280 HydrophobicContact CD2-CG 3.85Å; F58-Y280 AromaticContact CE2-CD2 3.69Å; F58-Y280 HydrophobicContact CE2-CD2 3.69Å; F58-Y280 HydrophobicContact CE2-CE2 4.29Å; F58-Y280 HydrophobicContact CE2-CG 4.21Å; F58-Y280 HydrophobicContact CG-CG 4.39Å; F58-Y280 HydrophobicContact CZ-CD2 4.4Å; E276-Y280 HydrophobicContact CG-CD2 3.72Å; E276-Y280 HydrophobicContact CG-CE2 3.38Å; E276-Y280 VanDerWaalsContact O-CD2 3.26Å; E276-Y280 WeakPolarHBondContact O-CD2 3.31Å; E276-Y280 PolarHBondContact O-N 3.12Å; E276-Y280 WeakPolarHBondContact OE1-CE2 3.47Å; A277-Y280 PolarHBondContact O-N 3.3Å; Y280-L282 VanDerWaalsContact C-N 3.29Å; Y280-L282 PolarHBondContact O-N 3.4Å; Y280-I283 PolarHBondContact O-N 3.47Å; Y280-E284 WeakPolarHBondContact O-CB 3.34Å; Y280-E284 PolarHBondContact O-N 2.89Å
281	F	92.8	Very high	91.6	Very high	3 Å²	3	45.1 Å²	45.1	1%	0.013	23%	0.226	C	C	.	.	H	α-helix	trans	-64	-33.7	176	-77.1	-55.2	0	0	0	112.7	F58 P61 V112 V261 R264 I266 A277 E284 A285	F58-F281 HydrophobicContact CD1-CE1 4.14Å; F58-F281 HydrophobicContact CD1-CE2 4.05Å; F58-F281 AromaticContact CD1-CZ 3.84Å; F58-F281 HydrophobicContact CD1-CZ 3.84Å; F58-F281 HydrophobicContact CE1-CE2 4.16Å; F58-F281 HydrophobicContact CE1-CZ 4.29Å; P61-F281 HydrophobicContact CB-CE1 4.24Å; P61-F281 HydrophobicContact CG-CE1 4.02Å; V112-F281 HydrophobicContact CG2-CD2 3.54Å; V112-F281 HydrophobicContact CG2-CE2 3.56Å; V261-F281 HydrophobicContact CB-CD2 4.46Å; V261-F281 HydrophobicContact CB-CE1 4.22Å; V261-F281 HydrophobicContact CB-CE2 3.95Å; V261-F281 HydrophobicContact CB-CZ 3.81Å; V261-F281 HydrophobicContact CG1-CD1 3.92Å; V261-F281 HydrophobicContact CG1-CD2 4.23Å; V261-F281 HydrophobicContact CG1-CE1 3.85Å; V261-F281 HydrophobicContact CG1-CE2 4.13Å; V261-F281 HydrophobicContact CG1-CG 4.11Å; V261-F281 HydrophobicContact CG1-CZ 3.94Å; R264-F281 HydrophobicContact CB-CZ 4.13Å; R264-F281 HydrophobicContact CG-CE1 4.29Å; R264-F281 HydrophobicContact CG-CZ 3.81Å; I266-F281 HydrophobicContact CD1-CE2 3.95Å; A277-F281 HydrophobicContact CB-CD2 4.39Å; A277-F281 HydrophobicContact CB-CE2 4.4Å; A277-F281 VanDerWaalsContact O-CD2 3.23Å; A277-F281 WeakPolarHBondContact O-CD2 3.38Å; A277-F281 PolarHBondContact O-N 3.32Å; F281-E284 WeakPolarHBondContact CD1-OE2 3.46Å; F281-A285 WeakPolarHBondContact O-CB 3.49Å; F281-A285 PolarHBondContact O-N 3.08Å
282	L	93.7	Very high	92	Very high	59 Å²	59	38.3 Å²	38.3	31%	0.309	20%	0.2	S	C	.	.	H	α-helix	trans	-66	-46	173.6	177	59.9	0	0	0	111.6	R105 N278 M279 Y280 E284 A286	R105-L282 HydrophobicContact CB-CD1 4.15Å; R105-L282 HydrophobicContact CG-CD1 3.91Å; N278-L282 VanDerWaalsContact O-CB 3.32Å; N278-L282 WeakPolarHBondContact O-CB 3.39Å; N278-L282 PolarHBondContact O-N 3.21Å; M279-L282 PolarHBondContact O-N 2.75Å; Y280-L282 VanDerWaalsContact C-N 3.29Å; Y280-L282 PolarHBondContact O-N 3.4Å; L282-E284 VanDerWaalsContact C-N 3.34Å; L282-A286 VanDerWaalsContact O-CB 3.22Å; L282-A286 WeakPolarHBondContact O-CB 3.39Å; L282-A286 PolarHBondContact O-N 3.45Å
283	I	93.3	Very high	92.5	Very high	53 Å²	53	35.3 Å²	35.3	27%	0.272	18%	0.18	S	C	.	.	H	α-helix	trans	-61.7	-46.3	178.7	-68.2	167.7	0	0	0	109.9	F50 L55 M279 Y280 A286 I287	F50-I283 HydrophobicContact CD2-CD1 4.4Å; F50-I283 HydrophobicContact CE2-CD1 3.86Å; L55-I283 HydrophobicContact CD1-CB 4.38Å; L55-I283 HydrophobicContact CD1-CG2 3.93Å; M279-I283 HydrophobicContact CG-CD1 4.04Å; M279-I283 WeakPolarHBondContact O-CG1 3.45Å; M279-I283 PolarHBondContact O-N 3.23Å; Y280-I283 PolarHBondContact O-N 3.47Å; I283-A286 PolarHBondContact O-N 3.17Å; I283-I287 HydrophobicContact CG2-CD1 3.85Å; I283-I287 VanDerWaalsContact O-CG1 3.3Å; I283-I287 WeakPolarHBondContact O-CG1 3.3Å; I283-I287 PolarHBondContact O-N 2.86Å
284	E	93.6	Very high	93	Very high	2 Å²	2	37.3 Å²	37.3	1%	0.009	19%	0.19	C	C	.	.	H	α-helix	trans	-61.1	-51.9	178.2	-173.9	-160.1	168.3	0	0	112	F58 T59 G60 G62 Y280 F281 L282 A286 I287 A288	F58-E284 VanDerWaalsContact O-OE2 3.14Å; T59-E284 WeakPolarHBondContact CA-OE1 3.31Å; G60-E284 WeakPolarHBondContact CA-OE1 3.3Å; G60-E284 PolarHBondContact N-OE1 3.03Å; G62-E284 WeakPolarHBondContact CA-OE1 3.44Å; G62-E284 PolarHBondContact N-OE1 3.09Å; Y280-E284 WeakPolarHBondContact O-CB 3.34Å; Y280-E284 PolarHBondContact O-N 2.89Å; F281-E284 WeakPolarHBondContact CD1-OE2 3.46Å; L282-E284 VanDerWaalsContact C-N 3.34Å; E284-A286 VanDerWaalsContact C-N 3.26Å; E284-A286 PolarHBondContact O-N 3.22Å; E284-I287 PolarHBondContact O-N 3.01Å; E284-A288 WeakPolarHBondContact O-CB 3.38Å; E284-A288 PolarHBondContact O-N 2.99Å
285	A	94.1	Very high	93.3	Very high	1 Å²	1	37 Å²	37	1%	0.008	19%	0.188	C	C	.	.	H	α-helix	trans	-61.4	-36.4	178.9	0	0	0	0	0	111.8	M65 L101 F281 L289	M65-A285 HydrophobicContact CE-CB 3.97Å; L101-A285 HydrophobicContact CD1-CB 4.11Å; F281-A285 WeakPolarHBondContact O-CB 3.49Å; F281-A285 PolarHBondContact O-N 3.08Å; A285-L289 VanDerWaalsContact O-CB 3.32Å; A285-L289 WeakPolarHBondContact O-CB 3.42Å; A285-L289 WeakPolarHBondContact O-CG 3.38Å; A285-L289 PolarHBondContact O-N 3.14Å
286	A	95.7	Very high	93.6	Very high	28 Å²	28	28.2 Å²	28.2	23%	0.231	16%	0.155	C	C	.	.	H	α-helix	trans	-65.7	-43.2	175.4	0	0	0	0	0	112	L101 L282 I283 E284 S290	L101-A286 HydrophobicContact CD1-CB 4.24Å; L101-A286 HydrophobicContact CD2-CB 4.14Å; L282-A286 VanDerWaalsContact O-CB 3.22Å; L282-A286 WeakPolarHBondContact O-CB 3.39Å; L282-A286 PolarHBondContact O-N 3.45Å; I283-A286 PolarHBondContact O-N 3.17Å; E284-A286 VanDerWaalsContact C-N 3.26Å; E284-A286 PolarHBondContact O-N 3.22Å; A286-S290 VanDerWaalsContact O-CB 3.29Å; A286-S290 WeakPolarHBondContact O-CB 3.28Å; A286-S290 PolarHBondContact O-N 3.45Å; A286-S290 PolarHBondContact O-OG 3.45Å
287	I	94.8	Very high	93.9	Very high	79 Å²	79	27.4 Å²	27.4	41%	0.405	15%	0.152	S	C	.	.	H	α-helix	trans	-63.6	-49.6	175.9	-68.5	165.8	0	0	0	110.1	F63 I283 E284 L289 S290 V291	F63-I287 HydrophobicContact CZ-CG2 4.25Å; I283-I287 HydrophobicContact CG2-CD1 3.85Å; I283-I287 VanDerWaalsContact O-CG1 3.3Å; I283-I287 WeakPolarHBondContact O-CG1 3.3Å; I283-I287 PolarHBondContact O-N 2.86Å; E284-I287 PolarHBondContact O-N 3.01Å; I287-L289 PolarHBondContact O-N 3.06Å; I287-S290 WeakPolarHBondContact O-CB 3.29Å; I287-S290 PolarHBondContact O-N 2.79Å; I287-V291 PolarHBondContact O-N 2.97Å
288	A	93.9	Very high	94.1	Very high	0 Å²	0	29.4 Å²	29.4	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-61.5	-47.4	-177.7	0	0	0	0	0	111.9	G62 F63 E284 S290 V291 S292	G62-A288 WeakPolarHBondContact O-CB 3.29Å; F63-A288 HydrophobicContact CD1-CB 4.05Å; F63-A288 HydrophobicContact CD2-CB 4.42Å; F63-A288 HydrophobicContact CE1-CB 4.25Å; F63-A288 HydrophobicContact CG-CB 4.15Å; E284-A288 WeakPolarHBondContact O-CB 3.38Å; E284-A288 PolarHBondContact O-N 2.99Å; A288-S290 VanDerWaalsContact C-N 3.31Å; A288-S290 PolarHBondContact O-N 3.4Å; A288-V291 WeakPolarHBondContact O-CB 3.46Å; A288-V291 PolarHBondContact O-N 3.23Å; A288-S292 PolarHBondContact O-N 3.19Å; A288-S292 PolarHBondContact O-OG 3.36Å
289	L	94.5	Very high	94.3	Very high	3 Å²	3	28.4 Å²	28.4	2%	0.016	16%	0.155	C	C	.	.	H	α-helix	trans	-69.3	-26.6	176.6	-69.6	-179.5	0	0	0	113.6	M65 F69 T97 L101 Q104 A285 I287 V291 S292 F293	M65-L289 HydrophobicContact CE-CD1 4.01Å; M65-L289 HydrophobicContact CE-CD2 4.26Å; M65-L289 HydrophobicContact CE-CG 4.03Å; M65-L289 HydrophobicContact SD-CD1 4.47Å; M65-L289 HydrophobicContact SD-CD2 3.94Å; M65-L289 HydrophobicContact SD-CG 4.37Å; F69-L289 HydrophobicContact CB-CD2 4.49Å; F69-L289 HydrophobicContact CD1-CD2 3.82Å; F69-L289 HydrophobicContact CD2-CD2 3.48Å; F69-L289 VanDerWaalsContact CD2-CD2 3.48Å; F69-L289 HydrophobicContact CE1-CD2 3.76Å; F69-L289 HydrophobicContact CE2-CD2 3.45Å; F69-L289 VanDerWaalsContact CE2-CD2 3.45Å; F69-L289 HydrophobicContact CG-CD2 3.68Å; F69-L289 HydrophobicContact CZ-CD1 4.28Å; F69-L289 HydrophobicContact CZ-CD2 3.6Å; T97-L289 HydrophobicContact CG2-CB 4.36Å; L101-L289 HydrophobicContact CB-CD1 3.7Å; L101-L289 HydrophobicContact CD1-CD1 3.84Å; L101-L289 HydrophobicContact CG-CD1 4.36Å; Q104-L289 HydrophobicContact CG-CD1 4.48Å; A285-L289 VanDerWaalsContact O-CB 3.32Å; A285-L289 WeakPolarHBondContact O-CB 3.42Å; A285-L289 WeakPolarHBondContact O-CG 3.38Å; A285-L289 PolarHBondContact O-N 3.14Å; I287-L289 PolarHBondContact O-N 3.06Å; L289-V291 VanDerWaalsContact C-N 3.35Å; L289-S292 PolarHBondContact O-N 3.05Å; L289-F293 VanDerWaalsContact O-CB 3.24Å; L289-F293 WeakPolarHBondContact O-CB 3.01Å; L289-F293 PolarHBondContact O-N 3.37Å
290	S	95.6	Very high	94.4	Very high	66 Å²	66	24.6 Å²	24.6	46%	0.462	14%	0.136	S	C	.	.	H	α-helix	trans	-66.4	-39.8	171.7	-61	0	0	0	0	111.2	A286 I287 A288 F293 I294	A286-S290 VanDerWaalsContact O-CB 3.29Å; A286-S290 WeakPolarHBondContact O-CB 3.28Å; A286-S290 PolarHBondContact O-N 3.45Å; A286-S290 PolarHBondContact O-OG 3.45Å; I287-S290 WeakPolarHBondContact O-CB 3.29Å; I287-S290 PolarHBondContact O-N 2.79Å; A288-S290 VanDerWaalsContact C-N 3.31Å; A288-S290 PolarHBondContact O-N 3.4Å; S290-F293 PolarHBondContact O-N 3.08Å; S290-I294 VanDerWaalsContact O-CG1 3.27Å; S290-I294 WeakPolarHBondContact O-CG1 3.21Å; S290-I294 PolarHBondContact O-N 3.45Å
291	V	95.1	Very high	94.5	Very high	48 Å²	48	24.6 Å²	24.6	29%	0.291	14%	0.136	S	C	.	.	H	α-helix	trans	-63.3	-47.3	173.7	174.8	0	0	0	0	110.2	I200 I287 A288 L289 F293 I294 I295	I200-V291 HydrophobicContact CG2-CG1 3.99Å; I287-V291 PolarHBondContact O-N 2.97Å; A288-V291 WeakPolarHBondContact O-CB 3.46Å; A288-V291 PolarHBondContact O-N 3.23Å; L289-V291 VanDerWaalsContact C-N 3.35Å; V291-F293 VanDerWaalsContact C-N 3.34Å; V291-F293 PolarHBondContact O-N 3.46Å; V291-I294 PolarHBondContact O-N 2.88Å; V291-I295 HydrophobicContact CG1-CD1 4.15Å; V291-I295 WeakPolarHBondContact O-CG1 3.48Å; V291-I295 PolarHBondContact O-N 3.01Å; V291-I295 VanDerWaalsContact O-N 3.12Å
292	S	94.8	Very high	94.4	Very high	1 Å²	1	24.5 Å²	24.5	1%	0.007	14%	0.136	C	C	.	.	H	α-helix	trans	-61.3	-42.4	177.5	-57.4	0	0	0	0	112.4	S66 A288 L289 I294 I295 N296	S66-S292 WeakPolarHBondContact CB-OG 3.44Å; S66-S292 PolarHBondContact O-OG 2.95Å; S66-S292 VanDerWaalsContact O-OG 3.05Å; A288-S292 PolarHBondContact O-N 3.19Å; A288-S292 PolarHBondContact O-OG 3.36Å; L289-S292 PolarHBondContact O-N 3.05Å; S292-I294 VanDerWaalsContact C-N 3.33Å; S292-I294 PolarHBondContact O-N 3.21Å; S292-I295 PolarHBondContact O-N 3.29Å; S292-N296 PolarHBondContact O-N 3.33Å; S292-N296 PolarHBondContact O-OD1 3.44Å
293	F	95.8	Very high	94.3	Very high	29 Å²	29	21.7 Å²	21.7	13%	0.127	12%	0.121	C	C	.	.	H	α-helix	trans	-59.1	-42.1	175.6	169.3	-101.8	0	0	0	112.6	L93 L94 T97 L225 L289 S290 V291 I295 N296 L297	L93-F293 HydrophobicContact CD2-CD2 4.33Å; L93-F293 HydrophobicContact CD2-CE2 3.95Å; L93-F293 HydrophobicContact CG-CD2 4.28Å; L93-F293 HydrophobicContact CG-CE2 4.07Å; L94-F293 HydrophobicContact CB-CE2 3.96Å; L94-F293 HydrophobicContact CB-CZ 4.27Å; L94-F293 HydrophobicContact CD1-CD2 4.47Å; L94-F293 HydrophobicContact CD1-CE1 4.19Å; L94-F293 HydrophobicContact CD1-CE2 3.93Å; L94-F293 HydrophobicContact CD1-CZ 3.8Å; T97-F293 HydrophobicContact CG2-CB 3.89Å; L225-F293 HydrophobicContact CD1-CE2 4.31Å; L225-F293 HydrophobicContact CD1-CZ 3.66Å; L289-F293 VanDerWaalsContact O-CB 3.24Å; L289-F293 WeakPolarHBondContact O-CB 3.01Å; L289-F293 PolarHBondContact O-N 3.37Å; S290-F293 PolarHBondContact O-N 3.08Å; V291-F293 VanDerWaalsContact C-N 3.34Å; V291-F293 PolarHBondContact O-N 3.46Å; F293-I295 VanDerWaalsContact C-N 3.31Å; F293-I295 PolarHBondContact O-N 3.06Å; F293-N296 PolarHBondContact O-N 3.17Å; F293-L297 HydrophobicContact CE1-CD2 4.19Å; F293-L297 HydrophobicContact CZ-CB 4.42Å; F293-L297 HydrophobicContact CZ-CD2 4.26Å; F293-L297 WeakPolarHBondContact O-CB 3.38Å; F293-L297 PolarHBondContact O-N 2.87Å
294	I	95.6	Very high	94.1	Very high	77 Å²	77	19.3 Å²	19.3	40%	0.395	11%	0.11	S	C	.	.	H	α-helix	trans	-63.1	-40.9	177.4	-70.9	165	0	0	0	110.7	S290 V291 S292 L297 F298	S290-I294 VanDerWaalsContact O-CG1 3.27Å; S290-I294 WeakPolarHBondContact O-CG1 3.21Å; S290-I294 PolarHBondContact O-N 3.45Å; V291-I294 PolarHBondContact O-N 2.88Å; S292-I294 VanDerWaalsContact C-N 3.33Å; S292-I294 PolarHBondContact O-N 3.21Å; I294-L297 WeakPolarHBondContact O-CB 3.46Å; I294-L297 PolarHBondContact O-N 3.34Å; I294-F298 HydrophobicContact CG2-CD1 4.48Å; I294-F298 HydrophobicContact CG2-CD2 4.16Å; I294-F298 HydrophobicContact CG2-CE1 3.91Å; I294-F298 HydrophobicContact CG2-CE2 3.55Å; I294-F298 HydrophobicContact CG2-CZ 3.4Å; I294-F298 VanDerWaalsContact CG2-CZ 3.4Å; I294-F298 WeakPolarHBondContact O-CD1 3.44Å; I294-F298 VanDerWaalsContact O-CG 3.23Å; I294-F298 WeakPolarHBondContact O-CG 3.2Å; I294-F298 PolarHBondContact O-N 2.95Å
295	I	95.3	Very high	93.8	Very high	3 Å²	3	23.6 Å²	23.6	2%	0.015	13%	0.13	C	C	.	.	H	α-helix	trans	-63.8	-48.4	177.2	-67.1	167.1	0	0	0	110.8	L70 I200 M203 A204 F207 V291 S292 F293 L297 F298 V299	L70-I295 HydrophobicContact CD1-CD1 3.68Å; L70-I295 HydrophobicContact CD2-CB 3.72Å; L70-I295 HydrophobicContact CD2-CD1 3.95Å; L70-I295 HydrophobicContact CD2-CG1 4.44Å; L70-I295 HydrophobicContact CD2-CG2 3.6Å; L70-I295 HydrophobicContact CG-CD1 4.49Å; I200-I295 HydrophobicContact CG2-CD1 4.36Å; M203-I295 HydrophobicContact CB-CD1 4.46Å; A204-I295 HydrophobicContact CB-CD1 4.07Å; A204-I295 HydrophobicContact CB-CG1 4.24Å; F207-I295 HydrophobicContact CB-CG2 4.47Å; F207-I295 HydrophobicContact CD2-CG2 3.53Å; F207-I295 HydrophobicContact CE2-CG2 4.22Å; F207-I295 HydrophobicContact CG-CG2 4.42Å; V291-I295 HydrophobicContact CG1-CD1 4.15Å; V291-I295 WeakPolarHBondContact O-CG1 3.48Å; V291-I295 PolarHBondContact O-N 3.01Å; V291-I295 VanDerWaalsContact O-N 3.12Å; S292-I295 PolarHBondContact O-N 3.29Å; F293-I295 VanDerWaalsContact C-N 3.31Å; F293-I295 PolarHBondContact O-N 3.06Å; I295-L297 VanDerWaalsContact C-N 3.3Å; I295-L297 PolarHBondContact O-N 3.18Å; I295-F298 WeakPolarHBondContact O-CB 3.21Å; I295-F298 PolarHBondContact O-N 2.96Å; I295-V299 PolarHBondContact O-N 3.39Å
296	N	95.3	Very high	93.3	Very high	2 Å²	2	24.3 Å²	24.3	1%	0.011	14%	0.136	C	C	.	.	H	α-helix	trans	-61.7	-39.8	178.1	-75.8	23.6	0	0	0	111.9	F69 L70 N74 D78 L93 S292 F293 F298 V299 M300	F69-N296 PolarHBondContact O-ND2 2.98Å; F69-N296 VanDerWaalsContact O-ND2 3.12Å; F69-N296 PolarHBondContact O-OD1 3.11Å; L70-N296 VanDerWaalsContact CD2-OD1 3.3Å; L70-N296 WeakPolarHBondContact CD2-OD1 3.25Å; N74-N296 PolarHBondContact ND2-ND2 3.14Å; N74-N296 PolarHBondContact OD1-ND2 2.8Å; D78-N296 WeakPolarHBondContact OD2-CB 3.32Å; D78-N296 PolarHBondContact OD2-ND2 2.99Å; L93-N296 HydrophobicContact CD1-CB 4.04Å; L93-N296 HydrophobicContact CD2-CB 4.21Å; S292-N296 PolarHBondContact O-N 3.33Å; S292-N296 PolarHBondContact O-OD1 3.44Å; F293-N296 PolarHBondContact O-N 3.17Å; N296-F298 VanDerWaalsContact C-N 3.33Å; N296-F298 PolarHBondContact O-N 3.48Å; N296-V299 PolarHBondContact O-N 3.44Å; N296-M300 WeakPolarHBondContact O-CB 3.44Å; N296-M300 PolarHBondContact O-N 3.26Å
297	L	95	Very high	92.6	Very high	17 Å²	17	23.3 Å²	23.3	9%	0.089	13%	0.126	C	C	.	.	H	α-helix	trans	-59.6	-42.8	172.5	175.3	63.2	0	0	0	111.5	L90 L93 L221 F293 I294 I295 A301	L90-L297 HydrophobicContact CD1-CD1 4.29Å; L90-L297 HydrophobicContact CD2-CD1 3.49Å; L90-L297 VanDerWaalsContact CD2-CD1 3.49Å; L90-L297 HydrophobicContact CG-CD1 4.46Å; L93-L297 HydrophobicContact CD2-CB 4.36Å; L221-L297 HydrophobicContact CD1-CD1 4.37Å; L221-L297 HydrophobicContact CD2-CD1 4.23Å; L221-L297 HydrophobicContact CD2-CD2 4.48Å; L221-L297 HydrophobicContact CG-CD1 4.35Å; F293-L297 HydrophobicContact CE1-CD2 4.19Å; F293-L297 HydrophobicContact CZ-CB 4.42Å; F293-L297 HydrophobicContact CZ-CD2 4.26Å; F293-L297 WeakPolarHBondContact O-CB 3.38Å; F293-L297 PolarHBondContact O-N 2.87Å; I294-L297 WeakPolarHBondContact O-CB 3.46Å; I294-L297 PolarHBondContact O-N 3.34Å; I295-L297 VanDerWaalsContact C-N 3.3Å; I295-L297 PolarHBondContact O-N 3.18Å; L297-A301 WeakPolarHBondContact O-CB 3.39Å; L297-A301 PolarHBondContact O-N 3.24Å
298	F	94.5	Very high	91.8	Very high	43 Å²	43	23.2 Å²	23.2	19%	0.189	12%	0.121	C	C	.	.	H	α-helix	trans	-62.3	-48.3	176.3	-68.1	-18.4	0	0	0	111.8	Y211 I294 I295 N296 A301 V302	Y211-F298 AromaticContact CD1-CD1 3.85Å; Y211-F298 HydrophobicContact CD1-CD1 3.85Å; Y211-F298 AromaticContact CD1-CE1 3.82Å; Y211-F298 HydrophobicContact CD1-CE1 3.82Å; Y211-F298 HydrophobicContact CD2-CB 4.16Å; Y211-F298 AromaticContact CD2-CD1 3.51Å; Y211-F298 HydrophobicContact CD2-CD1 3.51Å; Y211-F298 HydrophobicContact CD2-CE1 4.26Å; Y211-F298 HydrophobicContact CD2-CG 4.12Å; Y211-F298 HydrophobicContact CE1-CD1 4.19Å; Y211-F298 AromaticContact CE1-CE1 3.97Å; Y211-F298 HydrophobicContact CE1-CE1 3.97Å; Y211-F298 AromaticContact CE2-CD1 3.86Å; Y211-F298 HydrophobicContact CE2-CD1 3.86Å; Y211-F298 HydrophobicContact CE2-CE1 4.37Å; Y211-F298 HydrophobicContact CG-CB 4.28Å; Y211-F298 AromaticContact CG-CD1 3.48Å; Y211-F298 HydrophobicContact CG-CD1 3.48Å; Y211-F298 VanDerWaalsContact CG-CD1 3.48Å; Y211-F298 AromaticContact CG-CE1 3.96Å; Y211-F298 HydrophobicContact CG-CE1 3.96Å; Y211-F298 AromaticContact CG-CG 3.96Å; Y211-F298 HydrophobicContact CG-CG 3.96Å; I294-F298 HydrophobicContact CG2-CD1 4.48Å; I294-F298 HydrophobicContact CG2-CD2 4.16Å; I294-F298 HydrophobicContact CG2-CE1 3.91Å; I294-F298 HydrophobicContact CG2-CE2 3.55Å; I294-F298 HydrophobicContact CG2-CZ 3.4Å; I294-F298 VanDerWaalsContact CG2-CZ 3.4Å; I294-F298 WeakPolarHBondContact O-CD1 3.44Å; I294-F298 VanDerWaalsContact O-CG 3.23Å; I294-F298 WeakPolarHBondContact O-CG 3.2Å; I294-F298 PolarHBondContact O-N 2.95Å; I295-F298 WeakPolarHBondContact O-CB 3.21Å; I295-F298 PolarHBondContact O-N 2.96Å; N296-F298 VanDerWaalsContact C-N 3.33Å; N296-F298 PolarHBondContact O-N 3.48Å; F298-A301 PolarHBondContact O-N 2.85Å; F298-V302 WeakPolarHBondContact O-CB 3.38Å; F298-V302 WeakPolarHBondContact O-CG2 3.37Å; F298-V302 PolarHBondContact O-N 3.17Å
299	V	93.6	Very high	90.9	Very high	2 Å²	2	30.5 Å²	30.5	1%	0.012	16%	0.155	C	C	.	.	H	α-helix	trans	-58.5	-56.1	178.1	173.4	0	0	0	0	110.4	I75 D78 L79 F207 I295 N296 A301 V302 F303 W361	I75-V299 HydrophobicContact CG2-CG1 4.17Å; D78-V299 HydrophobicContact CB-CG1 4.32Å; L79-V299 HydrophobicContact CB-CG1 4.27Å; F207-V299 HydrophobicContact CB-CG2 4.23Å; F207-V299 HydrophobicContact CD1-CG2 4.18Å; F207-V299 HydrophobicContact CD2-CG2 4.15Å; F207-V299 HydrophobicContact CG-CG2 3.94Å; I295-V299 PolarHBondContact O-N 3.39Å; N296-V299 PolarHBondContact O-N 3.44Å; V299-A301 VanDerWaalsContact C-N 3.27Å; V299-A301 PolarHBondContact O-N 2.91Å; V299-V302 PolarHBondContact O-N 3.01Å; V299-F303 HydrophobicContact CG1-CD2 3.93Å; V299-F303 HydrophobicContact CG1-CE2 4.04Å; V299-F303 WeakPolarHBondContact O-CD2 3.22Å; V299-F303 PolarHBondContact O-N 3.07Å; V299-F303 VanDerWaalsContact O-N 3.14Å; V299-W361 HydrophobicContact CG1-CH2 4.33Å
300	M	93.7	Very high	90.1	Very high	0 Å²	0	33.7 Å²	33.7	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-59.6	-38.7	-178.3	-171.4	175.8	-63.1	0	0	112	D78 A81 L90 L93 I244 N296 G304	D78-M300 HydrophobicContact CB-CB 4.38Å; D78-M300 HydrophobicContact CB-CE 4.02Å; D78-M300 WeakPolarHBondContact O-CG 3.12Å; D78-M300 VanDerWaalsContact OD1-CE 3.29Å; D78-M300 WeakPolarHBondContact OD1-CE 3.35Å; A81-M300 HydrophobicContact CB-CE 3.91Å; L90-M300 HydrophobicContact CD2-CB 4.23Å; L90-M300 HydrophobicContact CD2-CG 3.99Å; L90-M300 HydrophobicContact CD2-SD 3.58Å; L90-M300 VanDerWaalsContact CD2-SD 3.58Å; L90-M300 HydrophobicContact CG-SD 4.27Å; L93-M300 HydrophobicContact CB-CE 4.15Å; L93-M300 HydrophobicContact CD1-CE 3.98Å; L93-M300 HydrophobicContact CD2-CE 4.24Å; L93-M300 HydrophobicContact CD2-SD 4.49Å; L93-M300 HydrophobicContact CG-CE 4.36Å; I244-M300 HydrophobicContact CD1-CE 3.75Å; I244-M300 HydrophobicContact CG1-CE 4.17Å; N296-M300 WeakPolarHBondContact O-CB 3.44Å; N296-M300 PolarHBondContact O-N 3.26Å; M300-G304 PolarHBondContact O-N 3.39Å
301	A	93	Very high	89.5	Confident	0 Å²	0	33 Å²	33	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-69.6	-41.4	179.4	0	0	0	0	0	113.3	F87 Y211 P216 L221 L297 F298 V299 G304 Q305	F87-A301 HydrophobicContact CE1-CB 4.26Å; Y211-A301 HydrophobicContact CD2-CB 4.06Å; Y211-A301 HydrophobicContact CE2-CB 3.77Å; P216-A301 HydrophobicContact CB-CB 4.43Å; P216-A301 HydrophobicContact CG-CB 4.24Å; L221-A301 HydrophobicContact CD1-CB 3.53Å; L297-A301 WeakPolarHBondContact O-CB 3.39Å; L297-A301 PolarHBondContact O-N 3.24Å; F298-A301 PolarHBondContact O-N 2.85Å; V299-A301 VanDerWaalsContact C-N 3.27Å; V299-A301 PolarHBondContact O-N 2.91Å; A301-G304 PolarHBondContact O-N 3.33Å; A301-Q305 WeakPolarHBondContact O-CB 3.17Å; A301-Q305 PolarHBondContact O-N 3.49Å
302	V	92.5	Very high	88.9	Confident	2 Å²	2	31.1 Å²	31.1	1%	0.012	15%	0.151	C	C	.	.	H	α-helix	trans	-60.3	-49.4	177.4	166.8	0	0	0	0	110.2	E210 Y211 A214 F298 V299 Q305 A306 L349	E210-V302 HydrophobicContact CB-CG1 4.48Å; E210-V302 HydrophobicContact CB-CG2 4.17Å; Y211-V302 VanDerWaalsContact CA-CG2 3.44Å; Y211-V302 HydrophobicContact CD2-CG2 4.44Å; A214-V302 HydrophobicContact CB-CB 4.48Å; A214-V302 HydrophobicContact CB-CG1 4.24Å; A214-V302 HydrophobicContact CB-CG2 4.04Å; F298-V302 WeakPolarHBondContact O-CB 3.38Å; F298-V302 WeakPolarHBondContact O-CG2 3.37Å; F298-V302 PolarHBondContact O-N 3.17Å; V299-V302 PolarHBondContact O-N 3.01Å; V302-Q305 PolarHBondContact O-N 2.95Å; V302-A306 VanDerWaalsContact O-CB 3.31Å; V302-A306 WeakPolarHBondContact O-CB 3.23Å; V302-A306 PolarHBondContact O-N 3.05Å; V302-L349 HydrophobicContact CG1-CD1 4.45Å; V302-L349 HydrophobicContact CG1-CD2 3.58Å
303	F	90.5	Very high	88.3	Confident	0 Å²	0	35.2 Å²	35.2	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-76.1	-29.7	-179	-68.4	-70.5	0	0	0	113.2	L79 V299 Q305 A306 F307 G345 L349 W361	L79-F303 HydrophobicContact CB-CD2 3.78Å; L79-F303 HydrophobicContact CB-CE2 4.21Å; L79-F303 HydrophobicContact CB-CG 4.18Å; L79-F303 HydrophobicContact CD1-CD1 4.02Å; L79-F303 HydrophobicContact CD1-CD2 3.78Å; L79-F303 HydrophobicContact CD1-CE1 3.75Å; L79-F303 HydrophobicContact CD1-CE2 3.53Å; L79-F303 HydrophobicContact CD1-CG 4.03Å; L79-F303 HydrophobicContact CD1-CZ 3.49Å; L79-F303 VanDerWaalsContact CD1-CZ 3.49Å; L79-F303 HydrophobicContact CG-CB 4.21Å; L79-F303 HydrophobicContact CG-CD1 3.94Å; L79-F303 HydrophobicContact CG-CD2 3.61Å; L79-F303 HydrophobicContact CG-CE1 4.2Å; L79-F303 HydrophobicContact CG-CE2 3.93Å; L79-F303 HydrophobicContact CG-CG 3.62Å; L79-F303 HydrophobicContact CG-CZ 4.19Å; V299-F303 HydrophobicContact CG1-CD2 3.93Å; V299-F303 HydrophobicContact CG1-CE2 4.04Å; V299-F303 WeakPolarHBondContact O-CD2 3.22Å; V299-F303 PolarHBondContact O-N 3.07Å; V299-F303 VanDerWaalsContact O-N 3.14Å; F303-Q305 VanDerWaalsContact C-N 3.33Å; F303-Q305 PolarHBondContact O-N 3.45Å; F303-A306 PolarHBondContact O-N 3.14Å; F303-F307 HydrophobicContact CB-CD2 4.47Å; F303-F307 AromaticContact CD1-CD2 3.75Å; F303-F307 HydrophobicContact CD1-CD2 3.75Å; F303-F307 AromaticContact CD1-CE2 3.72Å; F303-F307 HydrophobicContact CD1-CE2 3.72Å; F303-F307 HydrophobicContact CE1-CE2 4.15Å; F303-F307 WeakPolarHBondContact O-CB 3.15Å; F303-F307 PolarHBondContact O-N 3.34Å; F303-G345 VanDerWaalsContact CE1-CA 3.47Å; F303-L349 HydrophobicContact CE1-CD1 3.93Å; F303-L349 HydrophobicContact CE1-CD2 4.41Å; F303-L349 HydrophobicContact CE1-CG 4.02Å; F303-L349 HydrophobicContact CE2-CD1 4.43Å; F303-L349 HydrophobicContact CZ-CD1 3.55Å; F303-L349 HydrophobicContact CZ-CG 4.17Å; F303-W361 HydrophobicContact CE2-CE3 4.25Å; F303-W361 AromaticContact CE2-CH2 3.34Å; F303-W361 HydrophobicContact CE2-CH2 3.34Å; F303-W361 HydrophobicContact CE2-CZ2 4.1Å; F303-W361 AromaticContact CE2-CZ3 3.43Å; F303-W361 HydrophobicContact CE2-CZ3 3.43Å; F303-W361 VanDerWaalsContact CE2-CZ3 3.43Å; F303-W361 HydrophobicContact CZ-CD2 4.44Å; F303-W361 HydrophobicContact CZ-CE3 4.1Å; F303-W361 AromaticContact CZ-CH2 3.59Å; F303-W361 HydrophobicContact CZ-CH2 3.59Å; F303-W361 AromaticContact CZ-CZ2 3.92Å; F303-W361 HydrophobicContact CZ-CZ2 3.92Å; F303-W361 AromaticContact CZ-CZ3 3.68Å; F303-W361 HydrophobicContact CZ-CZ3 3.68Å
304	G	89.2	Confident	87.8	Confident	3 Å²	3	35 Å²	35	3%	0.031	17%	0.174	C	C	.	.	H	α-helix	trans	-60.1	-41.5	168	0	0	0	0	0	112.5	G82 M300 A301 Y308	G82-G304 VanDerWaalsContact O-CA 3.26Å; G82-G304 WeakPolarHBondContact O-CA 3.46Å; M300-G304 PolarHBondContact O-N 3.39Å; A301-G304 PolarHBondContact O-N 3.33Å; G304-Y308 WeakPolarHBondContact O-CB 3.44Å; G304-Y308 PolarHBondContact O-N 3.21Å
305	Q	87.6	Confident	87.2	Confident	92 Å²	92	31.4 Å²	31.4	43%	0.43	16%	0.156	S	C	.	.	H	α-helix	trans	-72.5	-38.5	175.5	-173.9	65.2	26.4	0	0	112.3	F87 P216 A301 V302 F303	F87-Q305 HydrophobicContact CZ-CB 4.34Å; P216-Q305 HydrophobicContact CB-CB 4.22Å; A301-Q305 WeakPolarHBondContact O-CB 3.17Å; A301-Q305 PolarHBondContact O-N 3.49Å; V302-Q305 PolarHBondContact O-N 2.95Å; F303-Q305 VanDerWaalsContact C-N 3.33Å; F303-Q305 PolarHBondContact O-N 3.45Å
306	A	83.7	Confident	86.7	Confident	15 Å²	15	33.3 Å²	33.3	12%	0.124	16%	0.164	C	C	.	.	H	α-helix	trans	-77.8	-37.2	-174	0	0	0	0	0	113.8	V302 F303 Q310 L352	V302-A306 VanDerWaalsContact O-CB 3.31Å; V302-A306 WeakPolarHBondContact O-CB 3.23Å; V302-A306 PolarHBondContact O-N 3.05Å; F303-A306 PolarHBondContact O-N 3.14Å; A306-Q310 WeakPolarHBondContact O-CG 3.04Å; A306-L352 HydrophobicContact CB-CD1 4.06Å
307	F	80.4	Confident	86.3	Confident	7 Å²	7	36.6 Å²	36.6	3%	0.031	18%	0.182	C	C	.	.	H	α-helix	trans	-115.8	-13.6	-170.7	-78.3	-71.5	0	0	0	115.9	A83 F303 Q309 Q310 F331 V338 V340 I348	A83-F307 HydrophobicContact CB-CB 3.77Å; A83-F307 HydrophobicContact CB-CG 4.41Å; F303-F307 HydrophobicContact CB-CD2 4.47Å; F303-F307 AromaticContact CD1-CD2 3.75Å; F303-F307 HydrophobicContact CD1-CD2 3.75Å; F303-F307 AromaticContact CD1-CE2 3.72Å; F303-F307 HydrophobicContact CD1-CE2 3.72Å; F303-F307 HydrophobicContact CE1-CE2 4.15Å; F303-F307 WeakPolarHBondContact O-CB 3.15Å; F303-F307 PolarHBondContact O-N 3.34Å; F307-Q309 PolarHBondContact O-N 3.49Å; F307-Q310 WeakPolarHBondContact O-CB 3.17Å; F307-Q310 PolarHBondContact O-N 3.13Å; F307-F331 HydrophobicContact CE1-CE1 4.45Å; F307-V338 HydrophobicContact CD1-CB 4.22Å; F307-V338 HydrophobicContact CD1-CG1 4.32Å; F307-V338 HydrophobicContact CD1-CG2 4.39Å; F307-V338 HydrophobicContact CE1-CB 4.33Å; F307-V338 HydrophobicContact CE1-CG1 3.96Å; F307-V338 HydrophobicContact CE1-CG2 4.48Å; F307-V340 HydrophobicContact CB-CG2 4.25Å; F307-V340 HydrophobicContact CD1-CG2 3.75Å; F307-V340 HydrophobicContact CD2-CG1 3.94Å; F307-V340 HydrophobicContact CD2-CG2 3.84Å; F307-V340 HydrophobicContact CE1-CG1 4.4Å; F307-V340 HydrophobicContact CE1-CG2 3.9Å; F307-V340 HydrophobicContact CE2-CB 4.35Å; F307-V340 HydrophobicContact CE2-CG1 3.39Å; F307-V340 HydrophobicContact CE2-CG2 3.95Å; F307-V340 HydrophobicContact CG-CG2 3.71Å; F307-V340 HydrophobicContact CZ-CG1 3.65Å; F307-V340 HydrophobicContact CZ-CG2 3.97Å; F307-I348 HydrophobicContact CD2-CG2 4.26Å; F307-I348 HydrophobicContact CE1-CB 4.29Å; F307-I348 HydrophobicContact CE1-CG1 4.11Å; F307-I348 HydrophobicContact CE1-CG2 4.15Å; F307-I348 HydrophobicContact CE2-CB 4.19Å; F307-I348 HydrophobicContact CE2-CG2 3.21Å; F307-I348 HydrophobicContact CZ-CB 3.6Å; F307-I348 HydrophobicContact CZ-CG1 3.89Å; F307-I348 HydrophobicContact CZ-CG2 3.15Å
308	Y	77.6	Confident	85.9	Confident	77 Å²	77	38.6 Å²	38.6	30%	0.302	19%	0.192	S	C	.	.	T	Hydrogen-bonded Turn	trans	-59.2	119.6	-175.3	-173.4	-113.9	0	0	0	111.1	A85 G86 K88 G304 Q310	A85-Y308 VanDerWaalsContact C-CE2 3.48Å; G86-Y308 VanDerWaalsContact CA-CD2 3.47Å; K88-Y308 WeakPolarHBondContact CE-OH 3.27Å; K88-Y308 PolarHBondContact NZ-OH 2.7Å; G304-Y308 WeakPolarHBondContact O-CB 3.44Å; G304-Y308 PolarHBondContact O-N 3.21Å; Y308-Q310 VanDerWaalsContact C-N 3.26Å; Y308-Q310 PolarHBondContact O-N 3.39Å
309	Q	75.1	Confident	85.5	Confident	153 Å²	153	36.6 Å²	36.6	72%	0.715	18%	0.183	S	C	*	.	T	Hydrogen-bonded Turn	trans	63.7	17.1	-175.6	-56.2	-178	-22.1	0	0	116.2	F307	F307-Q309 PolarHBondContact O-N 3.49Å
310	Q	78.7	Confident	85.2	Confident	71 Å²	71	38.4 Å²	38.4	33%	0.332	20%	0.198	S	C	.	.			trans	-80	141	174.4	-65	-66.8	-8.6	0	0	112	A306 F307 Y308 V338	A306-Q310 WeakPolarHBondContact O-CG 3.04Å; F307-Q310 WeakPolarHBondContact O-CB 3.17Å; F307-Q310 PolarHBondContact O-N 3.13Å; Y308-Q310 VanDerWaalsContact C-N 3.26Å; Y308-Q310 PolarHBondContact O-N 3.39Å; Q310-V338 PolarHBondContact O-N 3.21Å
311	T	82.6	Confident	84.8	Confident	50 Å²	50	45.5 Å²	45.5	31%	0.307	24%	0.236	S	C	.	.	B	Isolated β-bridge	trans	-92.4	155.4	172.7	60	0	0	0	0	110.8	Q313 A314 A315	T311-Q313 PolarHBondContact O-N 2.97Å; T311-A314 WeakPolarHBondContact O-CB 3.34Å; T311-A314 PolarHBondContact O-N 3.49Å; T311-A314 PolarHBondContact OG1-N 3.33Å; T311-A315 PolarHBondContact O-N 3.31Å; T311-A315 VanDerWaalsContact O-N 3.12Å
312	N	82.8	Confident	84.5	Confident	9 Å²	9	46.6 Å²	46.6	5%	0.048	24%	0.244	C	C	.	.	H	α-helix	trans	-60.1	-32.6	177.6	-66.5	-69.6	0	0	0	112.3	A315 F316 P332 N334 A336 T337 V338	N312-A315 PolarHBondContact O-N 3.08Å; N312-F316 WeakPolarHBondContact O-CB 3.37Å; N312-F316 PolarHBondContact O-N 3.04Å; N312-P332 HydrophobicContact CB-CG 4.23Å; N312-P332 WeakPolarHBondContact CB-O 3.25Å; N312-N334 WeakPolarHBondContact CB-OD1 3.46Å; N312-N334 PolarHBondContact ND2-OD1 2.93Å; N312-A336 PolarHBondContact N-O 3.01Å; N312-A336 VanDerWaalsContact N-O 3.13Å; N312-A336 PolarHBondContact ND2-O 3.34Å; N312-T337 PolarHBondContact ND2-O 3.31Å; N312-V338 HydrophobicContact CB-CG2 4.34Å; N312-V338 WeakPolarHBondContact OD1-CA 3.45Å; N312-V338 WeakPolarHBondContact OD1-CG1 3.13Å; N312-V338 WeakPolarHBondContact OD1-CG2 2.81Å
313	Q	82.3	Confident	84	Confident	87 Å²	87	50.6 Å²	50.6	41%	0.407	27%	0.272	S	S	.	.	H	α-helix	trans	-64.1	-39.6	173.5	-169.9	177.8	8.1	0	0	112.8	T311 F316 N317 M333 N334 N335	T311-Q313 PolarHBondContact O-N 2.97Å; Q313-F316 PolarHBondContact O-N 2.84Å; Q313-N317 VanDerWaalsContact O-CG 3.23Å; Q313-N317 PolarHBondContact O-N 3.11Å; Q313-N317 PolarHBondContact O-ND2 3.12Å; Q313-M333 HydrophobicContact CG-SD 4.43Å; Q313-N334 PolarHBondContact N-O 3.48Å; Q313-N335 PolarHBondContact OE1-OD1 3.47Å
314	A	83.8	Confident	83.6	Confident	25 Å²	25	51.4 Å²	51.4	21%	0.207	28%	0.276	C	S	.	.	H	α-helix	trans	-64.6	-46.4	176.6	0	0	0	0	0	110.9	T311 F316 N317 I318	T311-A314 WeakPolarHBondContact O-CB 3.34Å; T311-A314 PolarHBondContact O-N 3.49Å; T311-A314 PolarHBondContact OG1-N 3.33Å; A314-F316 VanDerWaalsContact C-N 3.34Å; A314-F316 PolarHBondContact O-N 3.02Å; A314-N317 PolarHBondContact O-N 3.19Å; A314-I318 WeakPolarHBondContact O-CD1 3.41Å; A314-I318 VanDerWaalsContact O-CG1 3.28Å; A314-I318 WeakPolarHBondContact O-CG1 3.2Å; A314-I318 PolarHBondContact O-N 2.89Å
315	A	83.3	Confident	83.2	Confident	2 Å²	2	56.5 Å²	56.5	2%	0.017	30%	0.299	C	S	.	.	H	α-helix	trans	-59.5	-43.1	175.5	0	0	0	0	0	112.2	T311 N312 N317 I318 C319 F331 V338 I348	T311-A315 PolarHBondContact O-N 3.31Å; T311-A315 VanDerWaalsContact O-N 3.12Å; N312-A315 PolarHBondContact O-N 3.08Å; A315-N317 PolarHBondContact O-N 3.11Å; A315-I318 PolarHBondContact O-N 3.15Å; A315-C319 PolarHBondContact O-N 3.13Å; A315-C319 VanDerWaalsContact O-N 3.08Å; A315-F331 HydrophobicContact CB-CB 4.45Å; A315-F331 HydrophobicContact CB-CD1 3.82Å; A315-F331 HydrophobicContact CB-CD2 4.37Å; A315-F331 HydrophobicContact CB-CE1 4.15Å; A315-F331 HydrophobicContact CB-CG 3.94Å; A315-V338 HydrophobicContact CB-CG2 4.33Å; A315-I348 HydrophobicContact CB-CD1 4.1Å
316	F	86.3	Confident	83	Confident	42 Å²	42	57.2 Å²	57.2	18%	0.184	31%	0.306	C	S	.	.	H	α-helix	trans	-58.2	-49.9	175.1	-176.7	-79.3	0	0	0	111.6	N312 Q313 A314 I318 C319 A320 A328 F331 M333	N312-F316 WeakPolarHBondContact O-CB 3.37Å; N312-F316 PolarHBondContact O-N 3.04Å; Q313-F316 PolarHBondContact O-N 2.84Å; A314-F316 VanDerWaalsContact C-N 3.34Å; A314-F316 PolarHBondContact O-N 3.02Å; F316-I318 VanDerWaalsContact C-N 3.31Å; F316-I318 PolarHBondContact O-N 3.11Å; F316-C319 PolarHBondContact O-N 2.96Å; F316-A320 HydrophobicContact CD1-CB 4.21Å; F316-A320 HydrophobicContact CE1-CB 3.88Å; F316-A320 VanDerWaalsContact O-CB 3.31Å; F316-A320 WeakPolarHBondContact O-CB 3.46Å; F316-A320 PolarHBondContact O-N 3.09Å; F316-A328 HydrophobicContact CD2-CB 4.07Å; F316-A328 WeakPolarHBondContact CD2-O 3.15Å; F316-A328 HydrophobicContact CE1-CB 4.41Å; F316-A328 HydrophobicContact CE2-CB 3.78Å; F316-A328 WeakPolarHBondContact CE2-O 3.46Å; F316-A328 HydrophobicContact CZ-CB 3.95Å; F316-F331 HydrophobicContact CB-CB 4.27Å; F316-M333 HydrophobicContact CB-SD 3.9Å; F316-M333 HydrophobicContact CD1-CE 3.17Å; F316-M333 HydrophobicContact CD1-SD 3.55Å; F316-M333 VanDerWaalsContact CD1-SD 3.55Å; F316-M333 HydrophobicContact CD2-CE 4.06Å; F316-M333 HydrophobicContact CD2-CG 4.14Å; F316-M333 HydrophobicContact CD2-SD 3.9Å; F316-M333 HydrophobicContact CE1-CE 3.1Å; F316-M333 HydrophobicContact CE1-SD 4.08Å; F316-M333 HydrophobicContact CE2-CE 3.99Å; F316-M333 HydrophobicContact CE2-CG 4.38Å; F316-M333 HydrophobicContact CE2-SD 4.37Å; F316-M333 HydrophobicContact CG-CE 3.7Å; F316-M333 HydrophobicContact CG-CG 4.32Å; F316-M333 HydrophobicContact CG-SD 3.48Å; F316-M333 WeakPolarHBondContact CG-SD 3.41Å; F316-M333 HydrophobicContact CZ-CE 3.54Å; F316-M333 HydrophobicContact CZ-SD 4.46Å
317	N	86.6	Confident	82.9	Confident	72 Å²	72	58.2 Å²	58.2	39%	0.385	31%	0.307	S	S	.	.	H	α-helix	trans	-63.5	-38.2	-177	-71.7	-20.5	0	0	0	112.2	Q313 A314 A315 A320 N321	Q313-N317 VanDerWaalsContact O-CG 3.23Å; Q313-N317 PolarHBondContact O-N 3.11Å; Q313-N317 PolarHBondContact O-ND2 3.12Å; A314-N317 PolarHBondContact O-N 3.19Å; A315-N317 PolarHBondContact O-N 3.11Å; N317-A320 PolarHBondContact O-N 3.11Å; N317-N321 PolarHBondContact O-N 3.43Å; N317-N321 VanDerWaalsContact O-N 3.15Å
318	I	86.3	Confident	82.9	Confident	59 Å²	59	58 Å²	58	30%	0.303	31%	0.306	S	S	.	.	H	α-helix	trans	-61.2	-50.3	175.2	-69.3	163	0	0	0	109.8	A314 A315 F316 N321 S322 I348 C351 L352	A314-I318 WeakPolarHBondContact O-CD1 3.41Å; A314-I318 VanDerWaalsContact O-CG1 3.28Å; A314-I318 WeakPolarHBondContact O-CG1 3.2Å; A314-I318 PolarHBondContact O-N 2.89Å; A315-I318 PolarHBondContact O-N 3.15Å; F316-I318 VanDerWaalsContact C-N 3.31Å; F316-I318 PolarHBondContact O-N 3.11Å; I318-N321 PolarHBondContact O-N 3.09Å; I318-S322 PolarHBondContact O-N 3.46Å; I318-I348 HydrophobicContact CG2-CD1 4.47Å; I318-C351 HydrophobicContact CG2-CB 4.16Å; I318-L352 HydrophobicContact CD1-CD2 4.23Å; I318-L352 HydrophobicContact CG2-CD2 3.64Å; I318-L352 HydrophobicContact CG2-CG 4.09Å
319	C	86.1	Confident	83.1	Confident	0 Å²	0	62.7 Å²	62.7	0%	0	33%	0.328	C	S	.	.	H	α-helix	trans	-66.5	-38.6	179.3	-76.3	0	0	0	0	113.1	A315 F316 N321 S322 H325 A328 C351	A315-C319 PolarHBondContact O-N 3.13Å; A315-C319 VanDerWaalsContact O-N 3.08Å; F316-C319 PolarHBondContact O-N 2.96Å; C319-N321 VanDerWaalsContact C-N 3.29Å; C319-N321 PolarHBondContact O-N 3.13Å; C319-S322 WeakPolarHBondContact O-CB 3.29Å; C319-S322 PolarHBondContact O-N 2.67Å; C319-S322 VanDerWaalsContact O-N 3.1Å; C319-S322 PolarHBondContact O-OG 2.93Å; C319-H325 WeakPolarHBondContact O-CA 3.23Å; C319-A328 HydrophobicContact CB-CB 4.01Å; C319-C351 WeakPolarHBondContact CA-SG 3.24Å; C319-C351 HydrophobicContact CB-CB 3.96Å; C319-C351 WeakPolarHBondContact CB-SG 2.95Å; C319-C351 WeakPolarHBondContact SG-CB 3.37Å; C319-C351 CovalentContact SG-SG 2.05Å; C319-C351 PolarHBondContact SG-SG 2.83Å
320	A	87.2	Confident	83.4	Confident	40 Å²	40	57 Å²	57	33%	0.331	30%	0.302	S	S	.	.	H	α-helix	trans	-63.7	-33	179.2	0	0	0	0	0	113	F316 N317 S322 A328	F316-A320 HydrophobicContact CD1-CB 4.21Å; F316-A320 HydrophobicContact CE1-CB 3.88Å; F316-A320 VanDerWaalsContact O-CB 3.31Å; F316-A320 WeakPolarHBondContact O-CB 3.46Å; F316-A320 PolarHBondContact O-N 3.09Å; N317-A320 PolarHBondContact O-N 3.11Å; A320-S322 VanDerWaalsContact C-N 3.33Å; A320-A328 HydrophobicContact CB-CB 4.21Å
321	N	86.2	Confident	83.5	Confident	149 Å²	149	53.7 Å²	53.7	80%	0.797	29%	0.287	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.6	-5	176.6	-73.2	-16.9	0	0	0	113.6	N317 I318 C319	N317-N321 PolarHBondContact O-N 3.43Å; N317-N321 VanDerWaalsContact O-N 3.15Å; I318-N321 PolarHBondContact O-N 3.09Å; C319-N321 VanDerWaalsContact C-N 3.29Å; C319-N321 PolarHBondContact O-N 3.13Å
322	S	85.9	Confident	83.4	Confident	24 Å²	24	53.1 Å²	53.1	17%	0.168	28%	0.284	C	S	.	.	S	Bend	trans	-92.3	170.9	-178.7	80.2	0	0	0	0	112.2	I318 C319 A320 L324 H325	I318-S322 PolarHBondContact O-N 3.46Å; C319-S322 WeakPolarHBondContact O-CB 3.29Å; C319-S322 PolarHBondContact O-N 2.67Å; C319-S322 VanDerWaalsContact O-N 3.1Å; C319-S322 PolarHBondContact O-OG 2.93Å; A320-S322 VanDerWaalsContact C-N 3.33Å; S322-L324 PolarHBondContact O-N 3.23Å; S322-L324 VanDerWaalsContact O-N 3.14Å; S322-L324 PolarHBondContact OG-N 3.4Å; S322-L324 VanDerWaalsContact OG-N 3.13Å; S322-H325 PolarHBondContact O-N 3.43Å
323	S	81.1	Confident	83.2	Confident	86 Å²	86	58.3 Å²	58.3	60%	0.601	31%	0.31	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.9	-15.4	171.7	55.7	0	0	0	0	113.6
324	L	83.4	Confident	83.1	Confident	17 Å²	17	57.4 Å²	57.4	9%	0.089	31%	0.307	C	S	.	.	T	Hydrogen-bonded Turn	trans	-100.2	32.5	-179.7	-70.2	108.4	0	0	0	113.3	S322 D326 Y327 G350 P355 L358	S322-L324 PolarHBondContact O-N 3.23Å; S322-L324 VanDerWaalsContact O-N 3.14Å; S322-L324 PolarHBondContact OG-N 3.4Å; S322-L324 VanDerWaalsContact OG-N 3.13Å; L324-D326 PolarHBondContact O-N 2.84Å; L324-Y327 HydrophobicContact CB-CD2 4Å; L324-Y327 HydrophobicContact CD2-CD2 3.8Å; L324-Y327 HydrophobicContact CD2-CE2 3.9Å; L324-Y327 HydrophobicContact CG-CD2 4.43Å; L324-Y327 WeakPolarHBondContact O-CB 3.39Å; L324-Y327 PolarHBondContact O-N 3.45Å; L324-G350 VanDerWaalsContact CD1-O 3.32Å; L324-G350 WeakPolarHBondContact CD1-O 3.4Å; L324-P355 HydrophobicContact CD1-CB 4.33Å; L324-P355 HydrophobicContact CD1-CG 3.87Å; L324-L358 HydrophobicContact CD2-CD1 3.58Å
325	H	80.3	Confident	82.9	Confident	109 Å²	109	62.4 Å²	62.4	51%	0.505	33%	0.331	S	S	.	.	G	3₁₀ helix	trans	-48.5	-31.3	-179	67.6	-72.2	0	0	0	115.4	C319 S322 Y327 A328	C319-H325 WeakPolarHBondContact O-CA 3.23Å; S322-H325 PolarHBondContact O-N 3.43Å; H325-Y327 PolarHBondContact O-N 2.99Å; H325-A328 VanDerWaalsContact O-CB 3.28Å; H325-A328 WeakPolarHBondContact O-CB 3.37Å; H325-A328 PolarHBondContact O-N 3.24Å; H325-A328 VanDerWaalsContact O-N 3.12Å
326	D	83.1	Confident	82.7	Confident	108 Å²	108	64.6 Å²	64.6	58%	0.578	35%	0.349	S	S	*	.	G	3₁₀ helix	trans	-58	-32.2	176.4	-72.8	-40.6	0	0	0	113.3	L324 A328	L324-D326 PolarHBondContact O-N 2.84Å; D326-A328 VanDerWaalsContact C-N 3.35Å
327	Y	82.8	Confident	82.1	Confident	35 Å²	35	67.9 Å²	67.9	14%	0.137	37%	0.373	C	S	.	.	G	3₁₀ helix	trans	-82.7	-9.4	-178.6	-69.1	-86.5	0	0	0	113.5	A162 L324 H325 K329 I330 V347	A162-Y327 WeakPolarHBondContact CA-OH 3.42Å; L324-Y327 HydrophobicContact CB-CD2 4Å; L324-Y327 HydrophobicContact CD2-CD2 3.8Å; L324-Y327 HydrophobicContact CD2-CE2 3.9Å; L324-Y327 HydrophobicContact CG-CD2 4.43Å; L324-Y327 WeakPolarHBondContact O-CB 3.39Å; L324-Y327 PolarHBondContact O-N 3.45Å; H325-Y327 PolarHBondContact O-N 2.99Å; Y327-K329 PolarHBondContact O-N 3.06Å; Y327-K329 VanDerWaalsContact O-N 3.1Å; Y327-I330 HydrophobicContact CD1-CD1 3.61Å; Y327-I330 HydrophobicContact CG-CD1 4.31Å; Y327-I330 WeakPolarHBondContact O-CB 3.5Å; Y327-I330 WeakPolarHBondContact O-CD1 3.49Å; Y327-I330 WeakPolarHBondContact O-CG1 3.03Å; Y327-I330 PolarHBondContact O-N 3.28Å; Y327-I330 VanDerWaalsContact O-N 3.13Å; Y327-V347 HydrophobicContact CD1-CG1 4.39Å; Y327-V347 HydrophobicContact CD1-CG2 3.84Å; Y327-V347 HydrophobicContact CE1-CG2 4.42Å; Y327-V347 HydrophobicContact CG-CG1 4.21Å; Y327-V347 HydrophobicContact CG-CG2 4.41Å
328	A	80.3	Confident	81.4	Confident	3 Å²	3	65.1 Å²	65.1	3%	0.025	36%	0.358	C	S	.	.	G	3₁₀ helix	trans	-57.2	-32.2	-179.6	0	0	0	0	0	112.4	F316 C319 A320 H325 D326 I330 F331	F316-A328 HydrophobicContact CD2-CB 4.07Å; F316-A328 WeakPolarHBondContact CD2-O 3.15Å; F316-A328 HydrophobicContact CE1-CB 4.41Å; F316-A328 HydrophobicContact CE2-CB 3.78Å; F316-A328 WeakPolarHBondContact CE2-O 3.46Å; F316-A328 HydrophobicContact CZ-CB 3.95Å; C319-A328 HydrophobicContact CB-CB 4.01Å; A320-A328 HydrophobicContact CB-CB 4.21Å; H325-A328 VanDerWaalsContact O-CB 3.28Å; H325-A328 WeakPolarHBondContact O-CB 3.37Å; H325-A328 PolarHBondContact O-N 3.24Å; H325-A328 VanDerWaalsContact O-N 3.12Å; D326-A328 VanDerWaalsContact C-N 3.35Å; A328-I330 PolarHBondContact O-N 3.15Å; A328-F331 PolarHBondContact O-N 3Å; A328-F331 VanDerWaalsContact O-N 3.15Å
329	K	81.5	Confident	80.7	Confident	175 Å²	175	66.2 Å²	66.2	76%	0.761	38%	0.376	S	S	*	.	G	3₁₀ helix	trans	-60.9	-16.3	-179.3	-62.7	174	-175.1	166.9	0	114.6	Y327 F331	Y327-K329 PolarHBondContact O-N 3.06Å; Y327-K329 VanDerWaalsContact O-N 3.1Å; K329-F331 VanDerWaalsContact C-N 3.33Å
330	I	80.6	Confident	80.4	Confident	33 Å²	33	66.7 Å²	66.7	17%	0.169	38%	0.379	C	S	.	.	G	3₁₀ helix	trans	-71.1	-33.7	179.2	-65.2	159.3	0	0	0	110.9	Y327 A328 P332 Y343 Q344 V347	Y327-I330 HydrophobicContact CD1-CD1 3.61Å; Y327-I330 HydrophobicContact CG-CD1 4.31Å; Y327-I330 WeakPolarHBondContact O-CB 3.5Å; Y327-I330 WeakPolarHBondContact O-CD1 3.49Å; Y327-I330 WeakPolarHBondContact O-CG1 3.03Å; Y327-I330 PolarHBondContact O-N 3.28Å; Y327-I330 VanDerWaalsContact O-N 3.13Å; A328-I330 PolarHBondContact O-N 3.15Å; I330-P332 WeakPolarHBondContact O-CD 3.48Å; I330-Y343 HydrophobicContact CD1-CD1 4.43Å; I330-Y343 HydrophobicContact CD1-CE1 3.41Å; I330-Y343 VanDerWaalsContact CD1-CE1 3.41Å; I330-Y343 HydrophobicContact CG1-CE1 4.08Å; I330-Y343 HydrophobicContact CG2-CD1 4.43Å; I330-Y343 HydrophobicContact CG2-CE1 4.24Å; I330-Q344 HydrophobicContact CG2-CG 3.74Å; I330-V347 HydrophobicContact CD1-CG1 4.41Å; I330-V347 HydrophobicContact CD1-CG2 4.09Å
331	F	81.6	Confident	80.3	Confident	2 Å²	2	65.3 Å²	65.3	1%	0.009	37%	0.366	C	S	.	.	S	Bend	trans	-85.4	117.3	178.4	-60.2	-75.5	0	0	0	109.6	F307 A315 F316 A328 K329 V338 Q344 V347 I348	F307-F331 HydrophobicContact CE1-CE1 4.45Å; A315-F331 HydrophobicContact CB-CB 4.45Å; A315-F331 HydrophobicContact CB-CD1 3.82Å; A315-F331 HydrophobicContact CB-CD2 4.37Å; A315-F331 HydrophobicContact CB-CE1 4.15Å; A315-F331 HydrophobicContact CB-CG 3.94Å; F316-F331 HydrophobicContact CB-CB 4.27Å; A328-F331 PolarHBondContact O-N 3Å; A328-F331 VanDerWaalsContact O-N 3.15Å; K329-F331 VanDerWaalsContact C-N 3.33Å; F331-V338 HydrophobicContact CD1-CG1 4.27Å; F331-V338 HydrophobicContact CE1-CG1 4.28Å; F331-Q344 HydrophobicContact CE1-CB 4.09Å; F331-Q344 HydrophobicContact CE1-CG 4.29Å; F331-Q344 HydrophobicContact CZ-CB 4.3Å; F331-V347 HydrophobicContact CE2-CG1 3.98Å; F331-V347 HydrophobicContact CZ-CG1 4.43Å; F331-I348 HydrophobicContact CE2-CD1 4.38Å; F331-I348 HydrophobicContact CZ-CB 4.21Å; F331-I348 HydrophobicContact CZ-CD1 4.23Å
332	P	79.3	Confident	80.4	Confident	38 Å²	38	58.3 Å²	58.3	25%	0.247	33%	0.329	C	S	.	.			trans	-66.4	139	179.1	26.4	-32.1	0	0	0	110.7	N312 I330 N334	N312-P332 HydrophobicContact CB-CG 4.23Å; N312-P332 WeakPolarHBondContact CB-O 3.25Å; I330-P332 WeakPolarHBondContact O-CD 3.48Å; P332-N334 PolarHBondContact O-N 3.26Å
333	M	78.4	Confident	80.5	Confident	119 Å²	119	58 Å²	58	59%	0.586	32%	0.324	S	S	*	.	S	Bend	trans	-74.7	74.7	176.8	-72.4	-75.9	-137.9	0	0	111.3	Q313 F316	Q313-M333 HydrophobicContact CG-SD 4.43Å; F316-M333 HydrophobicContact CB-SD 3.9Å; F316-M333 HydrophobicContact CD1-CE 3.17Å; F316-M333 HydrophobicContact CD1-SD 3.55Å; F316-M333 VanDerWaalsContact CD1-SD 3.55Å; F316-M333 HydrophobicContact CD2-CE 4.06Å; F316-M333 HydrophobicContact CD2-CG 4.14Å; F316-M333 HydrophobicContact CD2-SD 3.9Å; F316-M333 HydrophobicContact CE1-CE 3.1Å; F316-M333 HydrophobicContact CE1-SD 4.08Å; F316-M333 HydrophobicContact CE2-CE 3.99Å; F316-M333 HydrophobicContact CE2-CG 4.38Å; F316-M333 HydrophobicContact CE2-SD 4.37Å; F316-M333 HydrophobicContact CG-CE 3.7Å; F316-M333 HydrophobicContact CG-CG 4.32Å; F316-M333 HydrophobicContact CG-SD 3.48Å; F316-M333 WeakPolarHBondContact CG-SD 3.41Å; F316-M333 HydrophobicContact CZ-CE 3.54Å; F316-M333 HydrophobicContact CZ-SD 4.46Å
334	N	81.1	Confident	80.9	Confident	67 Å²	67	54.7 Å²	54.7	36%	0.358	30%	0.299	S	S	.	.	S	Bend	trans	-136.4	164.1	175.3	71.6	22.2	0	0	0	111.9	N312 Q313 P332 A336	N312-N334 WeakPolarHBondContact CB-OD1 3.46Å; N312-N334 PolarHBondContact ND2-OD1 2.93Å; Q313-N334 PolarHBondContact N-O 3.48Å; P332-N334 PolarHBondContact O-N 3.26Å; N334-A336 PolarHBondContact O-N 2.87Å; N334-A336 WeakPolarHBondContact OD1-CB 3.24Å; N334-A336 PolarHBondContact OD1-N 3.48Å
335	N	79.3	Confident	81	Confident	130 Å²	130	53.9 Å²	53.9	70%	0.695	30%	0.295	S	S	*	.	S	Bend	trans	-87	10	177.4	-72.1	-11.3	0	0	0	113.1	Q313	Q313-N335 PolarHBondContact OE1-OD1 3.47Å
336	A	78.7	Confident	81.4	Confident	49 Å²	49	48.7 Å²	48.7	41%	0.405	27%	0.271	S	S	.	.	S	Bend	trans	-75.1	156.3	175	0	0	0	0	0	110.2	N312 N334	N312-A336 PolarHBondContact N-O 3.01Å; N312-A336 VanDerWaalsContact N-O 3.13Å; N312-A336 PolarHBondContact ND2-O 3.34Å; N334-A336 PolarHBondContact O-N 2.87Å; N334-A336 WeakPolarHBondContact OD1-CB 3.24Å; N334-A336 PolarHBondContact OD1-N 3.48Å
337	T	75.1	Confident	81.7	Confident	110 Å²	110	43.5 Å²	43.5	68%	0.675	24%	0.243	S	C	*	.	B	Isolated β-bridge	trans	-61.4	144	168.2	48.5	0	0	0	0	109.8	N312 A339	N312-T337 PolarHBondContact ND2-O 3.31Å; T337-A339 PolarHBondContact O-N 3.28Å
338	V	71.3	Confident	81.9	Confident	14 Å²	14	42 Å²	42	9%	0.085	24%	0.237	C	C	.	.	P	Polyproline II helix	trans	-68.5	121.6	177.8	-169.5	0	0	0	0	109.2	F307 Q310 N312 A315 F331 V340	F307-V338 HydrophobicContact CD1-CB 4.22Å; F307-V338 HydrophobicContact CD1-CG1 4.32Å; F307-V338 HydrophobicContact CD1-CG2 4.39Å; F307-V338 HydrophobicContact CE1-CB 4.33Å; F307-V338 HydrophobicContact CE1-CG1 3.96Å; F307-V338 HydrophobicContact CE1-CG2 4.48Å; Q310-V338 PolarHBondContact O-N 3.21Å; N312-V338 HydrophobicContact CB-CG2 4.34Å; N312-V338 WeakPolarHBondContact OD1-CA 3.45Å; N312-V338 WeakPolarHBondContact OD1-CG1 3.13Å; N312-V338 WeakPolarHBondContact OD1-CG2 2.81Å; A315-V338 HydrophobicContact CB-CG2 4.33Å; F331-V338 HydrophobicContact CD1-CG1 4.27Å; F331-V338 HydrophobicContact CE1-CG1 4.28Å; V338-V340 HydrophobicContact CB-CG2 4.17Å; V338-V340 HydrophobicContact CG1-CG2 3.84Å
339	A	72.5	Confident	82.3	Confident	83 Å²	83	41.9 Å²	41.9	69%	0.686	24%	0.236	S	C	*	.	P	Polyproline II helix	trans	-80.6	118.5	159.7	0	0	0	0	0	105.9	T337 Q344	T337-A339 PolarHBondContact O-N 3.28Å; A339-Q344 PolarHBondContact O-OE1 3.41Å
340	V	78.6	Confident	82.6	Confident	10 Å²	10	33.5 Å²	33.5	6%	0.061	20%	0.2	C	C	.	.			trans	-105.4	132.5	-170.7	-166.5	0	0	0	0	109.3	L79 Q80 A83 F307 V338 Q344	L79-V340 HydrophobicContact CD2-CB 3.72Å; L79-V340 HydrophobicContact CD2-CG1 3.44Å; L79-V340 VanDerWaalsContact CD2-CG1 3.44Å; L79-V340 HydrophobicContact CG-CG1 4.28Å; Q80-V340 VanDerWaalsContact CG-O 3.3Å; Q80-V340 WeakPolarHBondContact CG-O 2.94Å; A83-V340 HydrophobicContact CB-CB 4.14Å; A83-V340 HydrophobicContact CB-CG2 3.56Å; F307-V340 HydrophobicContact CB-CG2 4.25Å; F307-V340 HydrophobicContact CD1-CG2 3.75Å; F307-V340 HydrophobicContact CD2-CG1 3.94Å; F307-V340 HydrophobicContact CD2-CG2 3.84Å; F307-V340 HydrophobicContact CE1-CG1 4.4Å; F307-V340 HydrophobicContact CE1-CG2 3.9Å; F307-V340 HydrophobicContact CE2-CB 4.35Å; F307-V340 HydrophobicContact CE2-CG1 3.39Å; F307-V340 HydrophobicContact CE2-CG2 3.95Å; F307-V340 HydrophobicContact CG-CG2 3.71Å; F307-V340 HydrophobicContact CZ-CG1 3.65Å; F307-V340 HydrophobicContact CZ-CG2 3.97Å; V338-V340 HydrophobicContact CB-CG2 4.17Å; V338-V340 HydrophobicContact CG1-CG2 3.84Å; V340-Q344 HydrophobicContact CG1-CB 4.45Å
341	D	85.9	Confident	83	Confident	11 Å²	11	32.5 Å²	32.5	6%	0.059	20%	0.196	C	C	.	.			trans	-115.8	173.8	168.9	62.7	32.8	0	0	0	111.6	Y343 Q344 G345 S422	D341-Y343 PolarHBondContact O-N 2.92Å; D341-Y343 WeakPolarHBondContact OD1-CA 3.42Å; D341-Y343 WeakPolarHBondContact OD1-CB 3.24Å; D341-Y343 PolarHBondContact OD1-N 2.95Å; D341-Q344 PolarHBondContact O-N 2.88Å; D341-Q344 VanDerWaalsContact OD1-CB 3.28Å; D341-Q344 WeakPolarHBondContact OD1-CB 2.97Å; D341-Q344 VanDerWaalsContact OD1-CG 3.25Å; D341-Q344 WeakPolarHBondContact OD1-CG 3.03Å; D341-Q344 PolarHBondContact OD1-N 3.32Å; D341-G345 PolarHBondContact O-N 3.23Å; D341-S422 VanDerWaalsContact CB-CB 3.5Å; D341-S422 WeakPolarHBondContact CB-OG 3.4Å; D341-S422 WeakPolarHBondContact OD2-CB 2.96Å; D341-S422 PolarHBondContact OD2-OG 3.25Å
342	I	88.4	Confident	83.2	Confident	1 Å²	1	35.6 Å²	35.6	1%	0.005	21%	0.212	C	C	.	.	H	α-helix	trans	-56	-35.2	179.6	-65.7	169.1	0	0	0	112.1	P72 E76 I155 G346 W361 L365	P72-I342 HydrophobicContact CB-CD1 4.12Å; E76-I342 HydrophobicContact CB-CD1 3.86Å; E76-I342 HydrophobicContact CB-CG1 3.8Å; E76-I342 HydrophobicContact CG-CD1 4.5Å; E76-I342 HydrophobicContact CG-CG1 4.14Å; E76-I342 VanDerWaalsContact OE2-CD1 3.23Å; E76-I342 WeakPolarHBondContact OE2-CD1 3.38Å; E76-I342 WeakPolarHBondContact OE2-CG1 3.44Å; I155-I342 HydrophobicContact CD1-CB 4.46Å; I155-I342 HydrophobicContact CG2-CG2 4.07Å; I342-G346 PolarHBondContact O-N 2.94Å; I342-G346 VanDerWaalsContact O-N 3.15Å; I342-W361 HydrophobicContact CG2-CZ2 4.12Å; I342-W361 PolarHBondContact O-NE1 3.2Å; I342-W361 VanDerWaalsContact O-NE1 3.12Å; I342-L365 HydrophobicContact CD1-CD1 4.25Å; I342-L365 HydrophobicContact CG2-CD1 3.68Å; I342-L365 HydrophobicContact CG2-CD2 3.27Å; I342-L365 HydrophobicContact CG2-CG 4.09Å
343	Y	88.5	Confident	83.6	Confident	17 Å²	17	37.3 Å²	37.3	7%	0.067	22%	0.216	C	C	.	.	H	α-helix	trans	-72.2	-52.2	-177.4	177.9	-104.3	0	0	0	111.4	I155 N158 L159 I330 D341 G345 G346 V347 L418	I155-Y343 HydrophobicContact CG2-CD2 4.1Å; N158-Y343 WeakPolarHBondContact OD1-CE2 3.25Å; L159-Y343 HydrophobicContact CD1-CD2 4.41Å; L159-Y343 HydrophobicContact CD2-CD2 3.68Å; L159-Y343 HydrophobicContact CD2-CE2 3.49Å; L159-Y343 VanDerWaalsContact CD2-CE2 3.49Å; L159-Y343 HydrophobicContact CG-CD2 3.95Å; L159-Y343 HydrophobicContact CG-CE2 4.07Å; I330-Y343 HydrophobicContact CD1-CD1 4.43Å; I330-Y343 HydrophobicContact CD1-CE1 3.41Å; I330-Y343 VanDerWaalsContact CD1-CE1 3.41Å; I330-Y343 HydrophobicContact CG1-CE1 4.08Å; I330-Y343 HydrophobicContact CG2-CD1 4.43Å; I330-Y343 HydrophobicContact CG2-CE1 4.24Å; D341-Y343 PolarHBondContact O-N 2.92Å; D341-Y343 WeakPolarHBondContact OD1-CA 3.42Å; D341-Y343 WeakPolarHBondContact OD1-CB 3.24Å; D341-Y343 PolarHBondContact OD1-N 2.95Å; Y343-G345 VanDerWaalsContact C-N 3.25Å; Y343-G345 PolarHBondContact O-N 3.42Å; Y343-G346 PolarHBondContact O-N 2.93Å; Y343-V347 HydrophobicContact CE1-CG2 4.37Å; Y343-V347 WeakPolarHBondContact O-CG2 3.2Å; Y343-V347 PolarHBondContact O-N 2.89Å; Y343-L418 HydrophobicContact CD1-CD2 4.32Å; Y343-L418 HydrophobicContact CE1-CD1 4.22Å; Y343-L418 HydrophobicContact CE1-CD2 4.5Å; Y343-L418 HydrophobicContact CG-CD2 4.44Å
344	Q	87.5	Confident	84	Confident	17 Å²	17	32.7 Å²	32.7	8%	0.079	20%	0.198	C	C	.	.	H	α-helix	trans	-61	-36.1	175	-70.7	171.8	-22.1	0	0	111.7	I330 F331 A339 V340 D341 V347 I348	I330-Q344 HydrophobicContact CG2-CG 3.74Å; F331-Q344 HydrophobicContact CE1-CB 4.09Å; F331-Q344 HydrophobicContact CE1-CG 4.29Å; F331-Q344 HydrophobicContact CZ-CB 4.3Å; A339-Q344 PolarHBondContact O-OE1 3.41Å; V340-Q344 HydrophobicContact CG1-CB 4.45Å; D341-Q344 PolarHBondContact O-N 2.88Å; D341-Q344 VanDerWaalsContact OD1-CB 3.28Å; D341-Q344 WeakPolarHBondContact OD1-CB 2.97Å; D341-Q344 VanDerWaalsContact OD1-CG 3.25Å; D341-Q344 WeakPolarHBondContact OD1-CG 3.03Å; D341-Q344 PolarHBondContact OD1-N 3.32Å; Q344-V347 PolarHBondContact O-N 3.24Å; Q344-I348 PolarHBondContact O-N 3.28Å
345	G	87.1	Confident	84.4	Confident	0 Å²	0	32.1 Å²	32.1	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-56.9	-52.3	172.5	0	0	0	0	0	112.1	F303 D341 Y343 V347 I348 L349	F303-G345 VanDerWaalsContact CE1-CA 3.47Å; D341-G345 PolarHBondContact O-N 3.23Å; Y343-G345 VanDerWaalsContact C-N 3.25Å; Y343-G345 PolarHBondContact O-N 3.42Å; G345-V347 VanDerWaalsContact C-N 3.34Å; G345-V347 PolarHBondContact O-N 3.1Å; G345-I348 VanDerWaalsContact O-CG2 3.24Å; G345-I348 WeakPolarHBondContact O-CG2 3.4Å; G345-I348 PolarHBondContact O-N 3.2Å; G345-L349 WeakPolarHBondContact O-CG 3.34Å; G345-L349 PolarHBondContact O-N 2.99Å
346	G	88.4	Confident	84.9	Confident	0 Å²	0	28.6 Å²	28.6	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-61.9	-40	177.3	0	0	0	0	0	113.5	I342 Y343 G350	I342-G346 PolarHBondContact O-N 2.94Å; I342-G346 VanDerWaalsContact O-N 3.15Å; Y343-G346 PolarHBondContact O-N 2.93Å; G346-G350 PolarHBondContact O-N 3.07Å; G346-G350 VanDerWaalsContact O-N 3.12Å
347	V	89.1	Confident	85.5	Confident	0 Å²	0	26.3 Å²	26.3	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-64.3	-47.1	178.6	169.6	0	0	0	0	111.6	L159 Y327 I330 F331 Y343 Q344 G345 L349 G350 C351	L159-V347 HydrophobicContact CD2-CG2 4.07Å; Y327-V347 HydrophobicContact CD1-CG1 4.39Å; Y327-V347 HydrophobicContact CD1-CG2 3.84Å; Y327-V347 HydrophobicContact CE1-CG2 4.42Å; Y327-V347 HydrophobicContact CG-CG1 4.21Å; Y327-V347 HydrophobicContact CG-CG2 4.41Å; I330-V347 HydrophobicContact CD1-CG1 4.41Å; I330-V347 HydrophobicContact CD1-CG2 4.09Å; F331-V347 HydrophobicContact CE2-CG1 3.98Å; F331-V347 HydrophobicContact CZ-CG1 4.43Å; Y343-V347 HydrophobicContact CE1-CG2 4.37Å; Y343-V347 WeakPolarHBondContact O-CG2 3.2Å; Y343-V347 PolarHBondContact O-N 2.89Å; Q344-V347 PolarHBondContact O-N 3.24Å; G345-V347 VanDerWaalsContact C-N 3.34Å; G345-V347 PolarHBondContact O-N 3.1Å; V347-L349 VanDerWaalsContact C-N 3.3Å; V347-L349 PolarHBondContact O-N 2.91Å; V347-G350 WeakPolarHBondContact O-CA 3.35Å; V347-G350 PolarHBondContact O-N 3.18Å; V347-G350 VanDerWaalsContact O-N 3.16Å; V347-C351 PolarHBondContact O-N 3.32Å; V347-C351 PolarHBondContact O-SG 3.38Å
348	I	87.8	Confident	86.3	Confident	3 Å²	3	21.2 Å²	21.2	2%	0.015	14%	0.137	C	C	.	.	H	α-helix	trans	-65.3	-36.9	-177.9	-160.4	62.8	0	0	0	111.6	F307 A315 I318 F331 Q344 G345 G350 C351 L352	F307-I348 HydrophobicContact CD2-CG2 4.26Å; F307-I348 HydrophobicContact CE1-CB 4.29Å; F307-I348 HydrophobicContact CE1-CG1 4.11Å; F307-I348 HydrophobicContact CE1-CG2 4.15Å; F307-I348 HydrophobicContact CE2-CB 4.19Å; F307-I348 HydrophobicContact CE2-CG2 3.21Å; F307-I348 HydrophobicContact CZ-CB 3.6Å; F307-I348 HydrophobicContact CZ-CG1 3.89Å; F307-I348 HydrophobicContact CZ-CG2 3.15Å; A315-I348 HydrophobicContact CB-CD1 4.1Å; I318-I348 HydrophobicContact CG2-CD1 4.47Å; F331-I348 HydrophobicContact CE2-CD1 4.38Å; F331-I348 HydrophobicContact CZ-CB 4.21Å; F331-I348 HydrophobicContact CZ-CD1 4.23Å; Q344-I348 PolarHBondContact O-N 3.28Å; G345-I348 VanDerWaalsContact O-CG2 3.24Å; G345-I348 WeakPolarHBondContact O-CG2 3.4Å; G345-I348 PolarHBondContact O-N 3.2Å; I348-G350 VanDerWaalsContact C-N 3.26Å; I348-G350 PolarHBondContact O-N 3.04Å; I348-C351 HydrophobicContact CD1-CB 4.44Å; I348-C351 PolarHBondContact O-N 3.49Å; I348-C351 VanDerWaalsContact O-N 3.08Å; I348-L352 HydrophobicContact CG1-CD1 3.97Å; I348-L352 HydrophobicContact CG1-CG 4.31Å; I348-L352 WeakPolarHBondContact O-CB 3.12Å; I348-L352 WeakPolarHBondContact O-CG 3.26Å; I348-L352 PolarHBondContact O-N 3.02Å
349	L	88.4	Confident	87.3	Confident	0 Å²	0	25.1 Å²	25.1	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-62.7	-42	177	-70.7	176.3	0	0	0	109.4	E210 V302 F303 G345 V347 C351 L352 F353 A357 W361	E210-L349 HydrophobicContact CG-CD1 4.41Å; V302-L349 HydrophobicContact CG1-CD1 4.45Å; V302-L349 HydrophobicContact CG1-CD2 3.58Å; F303-L349 HydrophobicContact CE1-CD1 3.93Å; F303-L349 HydrophobicContact CE1-CD2 4.41Å; F303-L349 HydrophobicContact CE1-CG 4.02Å; F303-L349 HydrophobicContact CE2-CD1 4.43Å; F303-L349 HydrophobicContact CZ-CD1 3.55Å; F303-L349 HydrophobicContact CZ-CG 4.17Å; G345-L349 WeakPolarHBondContact O-CG 3.34Å; G345-L349 PolarHBondContact O-N 2.99Å; V347-L349 VanDerWaalsContact C-N 3.3Å; V347-L349 PolarHBondContact O-N 2.91Å; L349-C351 PolarHBondContact O-N 2.92Å; L349-L352 PolarHBondContact O-N 2.97Å; L349-F353 HydrophobicContact CD2-CD2 3.88Å; L349-F353 HydrophobicContact CD2-CE2 3.71Å; L349-F353 WeakPolarHBondContact O-CB 3.39Å; L349-F353 PolarHBondContact O-N 2.56Å; L349-A357 HydrophobicContact CB-CB 4.33Å; L349-W361 HydrophobicContact CD1-CB 4.46Å; L349-W361 HydrophobicContact CD1-CD2 4.17Å; L349-W361 HydrophobicContact CD1-CE3 3.91Å; L349-W361 HydrophobicContact CD1-CG 4.43Å
350	G	88	Confident	88.4	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-55.6	-46.2	169.3	0	0	0	0	0	113.6	L324 G346 V347 I348 G354	L324-G350 VanDerWaalsContact CD1-O 3.32Å; L324-G350 WeakPolarHBondContact CD1-O 3.4Å; G346-G350 PolarHBondContact O-N 3.07Å; G346-G350 VanDerWaalsContact O-N 3.12Å; V347-G350 WeakPolarHBondContact O-CA 3.35Å; V347-G350 PolarHBondContact O-N 3.18Å; V347-G350 VanDerWaalsContact O-N 3.16Å; I348-G350 VanDerWaalsContact C-N 3.26Å; I348-G350 PolarHBondContact O-N 3.04Å; G350-G354 WeakPolarHBondContact CA-O 3.47Å; G350-G354 CarbonylContact O-C 3.58Å; G350-G354 WeakPolarHBondContact O-CA 3.44Å; G350-G354 PolarHBondContact O-N 3.04Å
351	C	87.9	Confident	89.2	Confident	12 Å²	12	22.5 Å²	22.5	8%	0.081	13%	0.125	C	C	.	.	H	α-helix	trans	-68.7	-37.4	-178.9	-61.1	0	0	0	0	113	I318 C319 V347 I348 L349	I318-C351 HydrophobicContact CG2-CB 4.16Å; C319-C351 WeakPolarHBondContact CA-SG 3.24Å; C319-C351 HydrophobicContact CB-CB 3.96Å; C319-C351 WeakPolarHBondContact CB-SG 2.95Å; C319-C351 WeakPolarHBondContact SG-CB 3.37Å; C319-C351 CovalentContact SG-SG 2.05Å; C319-C351 PolarHBondContact SG-SG 2.83Å; V347-C351 PolarHBondContact O-N 3.32Å; V347-C351 PolarHBondContact O-SG 3.38Å; I348-C351 HydrophobicContact CD1-CB 4.44Å; I348-C351 PolarHBondContact O-N 3.49Å; I348-C351 VanDerWaalsContact O-N 3.08Å; L349-C351 PolarHBondContact O-N 2.92Å
352	L	86.9	Confident	89.6	Confident	67 Å²	67	22 Å²	22	35%	0.351	12%	0.122	S	C	.	.	H	α-helix	trans	-80.2	-44.5	-177.2	-75	170.5	0	0	0	112.8	A306 I318 I348 L349	A306-L352 HydrophobicContact CB-CD1 4.06Å; I318-L352 HydrophobicContact CD1-CD2 4.23Å; I318-L352 HydrophobicContact CG2-CD2 3.64Å; I318-L352 HydrophobicContact CG2-CG 4.09Å; I348-L352 HydrophobicContact CG1-CD1 3.97Å; I348-L352 HydrophobicContact CG1-CG 4.31Å; I348-L352 WeakPolarHBondContact O-CB 3.12Å; I348-L352 WeakPolarHBondContact O-CG 3.26Å; I348-L352 PolarHBondContact O-N 3.02Å; L349-L352 PolarHBondContact O-N 2.97Å
353	F	86.6	Confident	89.9	Confident	74 Å²	74	25.7 Å²	25.7	33%	0.325	14%	0.141	S	C	.	.	H	α-helix	trans	-113.9	-1.9	-168.9	-54	-59.1	0	0	0	113.3	V213 A214 L349 A357	V213-F353 HydrophobicContact CG1-CB 3.81Å; V213-F353 HydrophobicContact CG1-CD1 3.53Å; V213-F353 HydrophobicContact CG1-CD2 4.43Å; V213-F353 HydrophobicContact CG1-CE1 4.2Å; V213-F353 HydrophobicContact CG1-CG 3.67Å; A214-F353 HydrophobicContact CB-CE2 4.13Å; A214-F353 HydrophobicContact CB-CZ 3.85Å; L349-F353 HydrophobicContact CD2-CD2 3.88Å; L349-F353 HydrophobicContact CD2-CE2 3.71Å; L349-F353 WeakPolarHBondContact O-CB 3.39Å; L349-F353 PolarHBondContact O-N 2.56Å; F353-A357 HydrophobicContact CB-CB 3.87Å
354	G	87.9	Confident	90.2	Very high	21 Å²	21	24.9 Å²	24.9	22%	0.216	14%	0.137	C	C	.	.			trans	99.4	168.3	176.7	0	0	0	0	0	113.7	G350 A356 A357	G350-G354 WeakPolarHBondContact CA-O 3.47Å; G350-G354 CarbonylContact O-C 3.58Å; G350-G354 WeakPolarHBondContact O-CA 3.44Å; G350-G354 PolarHBondContact O-N 3.04Å; G354-A356 PolarHBondContact O-N 3.26Å; G354-A357 WeakPolarHBondContact O-CB 3.44Å; G354-A357 PolarHBondContact O-N 2.56Å
355	P	88.1	Confident	90.6	Very high	55 Å²	55	24 Å²	24	36%	0.357	13%	0.134	S	C	.	.	H	α-helix	trans	-56.2	-29.1	-173.9	-23.7	30.7	0	0	0	114.7	L324 A357 L358 Y359	L324-P355 HydrophobicContact CD1-CB 4.33Å; L324-P355 HydrophobicContact CD1-CG 3.87Å; P355-A357 VanDerWaalsContact C-N 3.31Å; P355-A357 PolarHBondContact O-N 3.33Å; P355-L358 PolarHBondContact O-N 2.76Å; P355-Y359 HydrophobicContact CB-CE2 4.41Å; P355-Y359 WeakPolarHBondContact O-CD2 3.35Å; P355-Y359 PolarHBondContact O-N 3.38Å
356	A	90.8	Very high	90.9	Very high	56 Å²	56	26 Å²	26	46%	0.463	14%	0.144	S	C	.	.	H	α-helix	trans	-59.6	-40.7	178.3	0	0	0	0	0	112.3	G354 L358 Y359 I360	G354-A356 PolarHBondContact O-N 3.26Å; A356-L358 PolarHBondContact O-N 3.41Å; A356-Y359 PolarHBondContact O-N 3.37Å; A356-I360 WeakPolarHBondContact O-CB 3.32Å; A356-I360 VanDerWaalsContact O-CG1 3.23Å; A356-I360 WeakPolarHBondContact O-CG1 3.38Å; A356-I360 PolarHBondContact O-N 3.1Å
357	A	90.3	Very high	91.2	Very high	2 Å²	2	26.3 Å²	26.3	2%	0.017	15%	0.146	C	C	.	.	H	α-helix	trans	-63.8	-40.5	179.8	0	0	0	0	0	111.9	E210 L349 F353 G354 P355 Y359 I360 W361	E210-A357 WeakPolarHBondContact OE1-CA 3.49Å; E210-A357 WeakPolarHBondContact OE1-CB 3.36Å; E210-A357 VanDerWaalsContact OE1-O 3.1Å; L349-A357 HydrophobicContact CB-CB 4.33Å; F353-A357 HydrophobicContact CB-CB 3.87Å; G354-A357 WeakPolarHBondContact O-CB 3.44Å; G354-A357 PolarHBondContact O-N 2.56Å; P355-A357 VanDerWaalsContact C-N 3.31Å; P355-A357 PolarHBondContact O-N 3.33Å; A357-Y359 PolarHBondContact O-N 3.08Å; A357-I360 PolarHBondContact O-N 3.46Å; A357-W361 WeakPolarHBondContact O-CB 3.32Å; A357-W361 PolarHBondContact O-N 3.03Å
358	L	92.1	Very high	91.4	Very high	2 Å²	2	26.3 Å²	26.3	1%	0.01	15%	0.146	C	C	.	.	H	α-helix	trans	-60.1	-44.8	174.7	178.9	161.1	0	0	0	111.8	L159 L324 P355 A356 A362	L159-L358 HydrophobicContact CB-CD2 4.18Å; L159-L358 HydrophobicContact CD2-CD1 4.45Å; L159-L358 HydrophobicContact CD2-CD2 4.48Å; L159-L358 HydrophobicContact CD2-CG 4.46Å; L324-L358 HydrophobicContact CD2-CD1 3.58Å; P355-L358 PolarHBondContact O-N 2.76Å; A356-L358 PolarHBondContact O-N 3.41Å; L358-A362 WeakPolarHBondContact O-CB 3.41Å; L358-A362 PolarHBondContact O-N 2.81Å
359	Y	93.6	Very high	91.6	Very high	97 Å²	97	26.1 Å²	26.1	38%	0.38	15%	0.146	S	C	.	.	H	α-helix	trans	-69.3	-38.3	178.7	-70.2	-62.8	0	0	0	112.3	L160 P355 A356 A357 A362 I363	L160-Y359 HydrophobicContact CD2-CD1 4.14Å; P355-Y359 HydrophobicContact CB-CE2 4.41Å; P355-Y359 WeakPolarHBondContact O-CD2 3.35Å; P355-Y359 PolarHBondContact O-N 3.38Å; A356-Y359 PolarHBondContact O-N 3.37Å; A357-Y359 PolarHBondContact O-N 3.08Å; Y359-A362 PolarHBondContact O-N 2.96Å; Y359-I363 VanDerWaalsContact O-CG1 3.29Å; Y359-I363 WeakPolarHBondContact O-CG1 3.27Å; Y359-I363 PolarHBondContact O-N 3.28Å
360	I	94.5	Very high	91.6	Very high	36 Å²	36	28 Å²	28	19%	0.185	16%	0.155	C	C	.	.	H	α-helix	trans	-62.6	-45.2	175.9	-71.9	169.3	0	0	0	110.4	T206 Y209 E210 A356 A357 A362 I363 G364	T206-I360 WeakPolarHBondContact CB-O 3.49Å; T206-I360 HydrophobicContact CG2-CG2 3.9Å; T206-I360 WeakPolarHBondContact CG2-O 3.3Å; T206-I360 WeakPolarHBondContact O-CG2 3.21Å; Y209-I360 HydrophobicContact CD1-CD1 3.45Å; Y209-I360 VanDerWaalsContact CD1-CD1 3.45Å; Y209-I360 HydrophobicContact CD1-CG2 4.21Å; Y209-I360 HydrophobicContact CE1-CD1 3.41Å; Y209-I360 VanDerWaalsContact CE1-CD1 3.41Å; Y209-I360 HydrophobicContact CG-CD1 4.14Å; E210-I360 HydrophobicContact CG-CG2 4.46Å; A356-I360 WeakPolarHBondContact O-CB 3.32Å; A356-I360 VanDerWaalsContact O-CG1 3.23Å; A356-I360 WeakPolarHBondContact O-CG1 3.38Å; A356-I360 PolarHBondContact O-N 3.1Å; A357-I360 PolarHBondContact O-N 3.46Å; I360-A362 PolarHBondContact O-N 3.45Å; I360-I363 PolarHBondContact O-N 3.44Å; I360-G364 PolarHBondContact O-N 3.17Å
361	W	94.5	Very high	91.7	Very high	2 Å²	2	28 Å²	28	1%	0.008	16%	0.155	C	C	.	.	H	α-helix	trans	-55.6	-49.5	171.9	177.2	-101.8	0	0	0	111.9	I75 L79 F207 V299 F303 I342 L349 A357 I363 G364 L365	I75-W361 HydrophobicContact CG2-CH2 3.59Å; I75-W361 HydrophobicContact CG2-CZ2 4.07Å; L79-W361 HydrophobicContact CD1-CH2 4.14Å; L79-W361 HydrophobicContact CD1-CZ2 3.98Å; F207-W361 AromaticContact CD1-CE3 3.88Å; F207-W361 HydrophobicContact CD1-CE3 3.88Å; F207-W361 AromaticContact CD1-CZ3 3.76Å; F207-W361 HydrophobicContact CD1-CZ3 3.76Å; F207-W361 HydrophobicContact CE1-CD2 4.36Å; F207-W361 AromaticContact CE1-CE3 3.54Å; F207-W361 HydrophobicContact CE1-CE3 3.54Å; F207-W361 HydrophobicContact CE1-CH2 4.25Å; F207-W361 AromaticContact CE1-CZ3 3.45Å; F207-W361 HydrophobicContact CE1-CZ3 3.45Å; F207-W361 VanDerWaalsContact CE1-CZ3 3.45Å; F207-W361 HydrophobicContact CZ-CZ3 4.41Å; V299-W361 HydrophobicContact CG1-CH2 4.33Å; F303-W361 HydrophobicContact CE2-CE3 4.25Å; F303-W361 AromaticContact CE2-CH2 3.34Å; F303-W361 HydrophobicContact CE2-CH2 3.34Å; F303-W361 HydrophobicContact CE2-CZ2 4.1Å; F303-W361 AromaticContact CE2-CZ3 3.43Å; F303-W361 HydrophobicContact CE2-CZ3 3.43Å; F303-W361 VanDerWaalsContact CE2-CZ3 3.43Å; F303-W361 HydrophobicContact CZ-CD2 4.44Å; F303-W361 HydrophobicContact CZ-CE3 4.1Å; F303-W361 AromaticContact CZ-CH2 3.59Å; F303-W361 HydrophobicContact CZ-CH2 3.59Å; F303-W361 AromaticContact CZ-CZ2 3.92Å; F303-W361 HydrophobicContact CZ-CZ2 3.92Å; F303-W361 AromaticContact CZ-CZ3 3.68Å; F303-W361 HydrophobicContact CZ-CZ3 3.68Å; I342-W361 HydrophobicContact CG2-CZ2 4.12Å; I342-W361 PolarHBondContact O-NE1 3.2Å; I342-W361 VanDerWaalsContact O-NE1 3.12Å; L349-W361 HydrophobicContact CD1-CB 4.46Å; L349-W361 HydrophobicContact CD1-CD2 4.17Å; L349-W361 HydrophobicContact CD1-CE3 3.91Å; L349-W361 HydrophobicContact CD1-CG 4.43Å; A357-W361 WeakPolarHBondContact O-CB 3.32Å; A357-W361 PolarHBondContact O-N 3.03Å; W361-I363 VanDerWaalsContact C-N 3.34Å; W361-I363 PolarHBondContact O-N 3.06Å; W361-G364 PolarHBondContact O-N 3.4Å; W361-L365 WeakPolarHBondContact O-CB 3.31Å; W361-L365 PolarHBondContact O-N 3.22Å
362	A	95	Very high	91.7	Very high	0 Å²	0	27.5 Å²	27.5	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-65.9	-34.2	-178.1	0	0	0	0	0	112.9	A156 L159 L160 L358 Y359 I360 L366	A156-A362 WeakPolarHBondContact CB-O 3.47Å; L159-A362 HydrophobicContact CB-CB 3.77Å; L159-A362 HydrophobicContact CD1-CB 4.39Å; L160-A362 HydrophobicContact CD2-CB 3.78Å; L160-A362 HydrophobicContact CG-CB 3.75Å; L358-A362 WeakPolarHBondContact O-CB 3.41Å; L358-A362 PolarHBondContact O-N 2.81Å; Y359-A362 PolarHBondContact O-N 2.96Å; I360-A362 PolarHBondContact O-N 3.45Å; A362-L366 WeakPolarHBondContact O-CB 3.26Å; A362-L366 PolarHBondContact O-N 3.39Å
363	I	95.6	Very high	91.6	Very high	78 Å²	78	24.4 Å²	24.4	40%	0.4	14%	0.135	S	C	.	.	H	α-helix	trans	-66.7	-44.8	173	-68.6	167.3	0	0	0	110.9	L160 I202 T206 Y359 I360 W361 L365 L366 A367	L160-I363 HydrophobicContact CD2-CG1 4Å; I202-I363 HydrophobicContact CG2-CG2 3.81Å; T206-I363 HydrophobicContact CG2-CB 4.44Å; T206-I363 HydrophobicContact CG2-CG2 4.22Å; Y359-I363 VanDerWaalsContact O-CG1 3.29Å; Y359-I363 WeakPolarHBondContact O-CG1 3.27Å; Y359-I363 PolarHBondContact O-N 3.28Å; I360-I363 PolarHBondContact O-N 3.44Å; W361-I363 VanDerWaalsContact C-N 3.34Å; W361-I363 PolarHBondContact O-N 3.06Å; I363-L365 VanDerWaalsContact C-N 3.34Å; I363-L366 PolarHBondContact O-N 3.34Å; I363-A367 PolarHBondContact O-N 3.2Å
364	G	95.1	Very high	91.4	Very high	0 Å²	0	21.2 Å²	21.2	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-60.9	-44.3	176.6	0	0	0	0	0	111.9	T206 I360 W361 A367 A368	T206-G364 WeakPolarHBondContact OG1-CA 3.31Å; I360-G364 PolarHBondContact O-N 3.17Å; W361-G364 PolarHBondContact O-N 3.4Å; G364-A367 PolarHBondContact O-N 2.87Å; G364-A368 PolarHBondContact O-N 3.32Å
365	L	93.9	Very high	91.3	Very high	0 Å²	0	20.3 Å²	20.3	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-64.3	-39.3	176.4	-176.1	66.2	0	0	0	112.5	P72 G152 I155 A156 I342 W361 I363 A368 G369	P72-L365 HydrophobicContact CB-CD1 4.13Å; P72-L365 HydrophobicContact CG-CD1 4.22Å; G152-L365 VanDerWaalsContact O-CD2 3.3Å; G152-L365 WeakPolarHBondContact O-CD2 3.33Å; G152-L365 WeakPolarHBondContact O-CG 3.47Å; I155-L365 HydrophobicContact CB-CD2 4.22Å; I155-L365 HydrophobicContact CG2-CD2 3.79Å; A156-L365 HydrophobicContact CB-CB 4.24Å; A156-L365 HydrophobicContact CB-CD2 3.99Å; A156-L365 HydrophobicContact CB-CG 4.11Å; I342-L365 HydrophobicContact CD1-CD1 4.25Å; I342-L365 HydrophobicContact CG2-CD1 3.68Å; I342-L365 HydrophobicContact CG2-CD2 3.27Å; I342-L365 HydrophobicContact CG2-CG 4.09Å; W361-L365 WeakPolarHBondContact O-CB 3.31Å; W361-L365 PolarHBondContact O-N 3.22Å; I363-L365 VanDerWaalsContact C-N 3.34Å; L365-A368 PolarHBondContact O-N 2.83Å; L365-G369 PolarHBondContact O-N 3.41Å
366	L	94.4	Very high	91.1	Very high	40 Å²	40	17.9 Å²	17.9	21%	0.209	10%	0.096	C	C	.	.	H	α-helix	trans	-63.4	-43	173.8	-174.9	64.1	0	0	0	110.9	T153 A156 F157 L160 A362 I363 G369 Q370	T153-L366 HydrophobicContact CG2-CD1 3.88Å; A156-L366 HydrophobicContact CB-CB 3.91Å; A156-L366 HydrophobicContact CB-CD1 4.33Å; F157-L366 HydrophobicContact CE1-CD1 4.33Å; F157-L366 HydrophobicContact CE2-CD1 4.03Å; F157-L366 HydrophobicContact CZ-CD1 3.9Å; L160-L366 HydrophobicContact CD1-CD2 3.98Å; A362-L366 WeakPolarHBondContact O-CB 3.26Å; A362-L366 PolarHBondContact O-N 3.39Å; I363-L366 PolarHBondContact O-N 3.34Å; L366-G369 PolarHBondContact O-N 2.88Å; L366-Q370 HydrophobicContact CD1-CG 4.28Å; L366-Q370 HydrophobicContact CG-CG 4.44Å; L366-Q370 WeakPolarHBondContact O-CB 3.2Å; L366-Q370 VanDerWaalsContact O-CG 3.25Å; L366-Q370 WeakPolarHBondContact O-CG 3.33Å; L366-Q370 PolarHBondContact O-N 1.99Å
367	A	94.1	Very high	90.8	Very high	7 Å²	7	15.5 Å²	15.5	6%	0.058	8%	0.076	C	C	.	.	H	α-helix	trans	-62.5	-43.4	176.9	0	0	0	0	0	111.9	L199 I202 M203 I363 G364 Q370 S371	L199-A367 HydrophobicContact CD2-CB 4.11Å; I202-A367 HydrophobicContact CB-CB 4.33Å; I202-A367 HydrophobicContact CG2-CB 3.97Å; M203-A367 HydrophobicContact CG-CB 3.89Å; I363-A367 PolarHBondContact O-N 3.2Å; G364-A367 PolarHBondContact O-N 2.87Å; A367-Q370 PolarHBondContact O-N 2.93Å; A367-S371 WeakPolarHBondContact O-CB 3.18Å; A367-S371 PolarHBondContact O-N 3.45Å; A367-S371 PolarHBondContact O-OG 3.49Å
368	A	93.2	Very high	90.5	Very high	0 Å²	0	15.7 Å²	15.7	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-57.3	-53.6	173.1	0	0	0	0	0	111.4	L70 P72 I75 M203 G364 L365 Q370 S371 S372	L70-A368 VanDerWaalsContact O-CB 3.23Å; L70-A368 WeakPolarHBondContact O-CB 3.3Å; P72-A368 HydrophobicContact CG-CB 4.3Å; I75-A368 HydrophobicContact CD1-CB 3.64Å; M203-A368 VanDerWaalsContact SD-CA 3.51Å; M203-A368 HydrophobicContact SD-CB 3.63Å; G364-A368 PolarHBondContact O-N 3.32Å; L365-A368 PolarHBondContact O-N 2.83Å; A368-Q370 VanDerWaalsContact C-N 3.28Å; A368-Q370 PolarHBondContact O-N 3.43Å; A368-S371 PolarHBondContact O-N 2.88Å; A368-S371 PolarHBondContact O-OG 2.99Å; A368-S372 PolarHBondContact O-N 3.32Å; A368-S372 VanDerWaalsContact O-N 3.1Å
369	G	91.8	Very high	90.3	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-69.4	-13.3	-179.6	0	0	0	0	0	115.4	T153 L365 L366 T373	T153-G369 WeakPolarHBondContact OG1-CA 3.31Å; T153-G369 PolarHBondContact OG1-O 3.27Å; L365-G369 PolarHBondContact O-N 3.41Å; L366-G369 PolarHBondContact O-N 2.88Å; G369-T373 PolarHBondContact O-OG1 2.92Å
370	Q	90.1	Very high	90	Very high	40 Å²	40	11 Å²	11	19%	0.187	6%	0.058	C	C	.	.	H	α-helix	trans	-92.9	-31	170	-68.8	-64.1	-74.9	0	0	111.8	D177 L366 A367 A368 T373	D177-Q370 VanDerWaalsContact CB-OE1 3.26Å; D177-Q370 PolarHBondContact OD2-NE2 3.38Å; D177-Q370 VanDerWaalsContact OD2-NE2 3.07Å; L366-Q370 HydrophobicContact CD1-CG 4.28Å; L366-Q370 HydrophobicContact CG-CG 4.44Å; L366-Q370 WeakPolarHBondContact O-CB 3.2Å; L366-Q370 VanDerWaalsContact O-CG 3.25Å; L366-Q370 WeakPolarHBondContact O-CG 3.33Å; L366-Q370 PolarHBondContact O-N 1.99Å; A367-Q370 PolarHBondContact O-N 2.93Å; A368-Q370 VanDerWaalsContact C-N 3.28Å; A368-Q370 PolarHBondContact O-N 3.43Å; Q370-T373 PolarHBondContact O-OG1 3.21Å
371	S	89.3	Confident	89.6	Confident	0 Å²	0	9.9 Å²	9.9	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-71.6	-34.2	179.2	68.5	0	0	0	0	112.4	I67 A367 A368 T373 T375	I67-S371 VanDerWaalsContact CG2-CB 3.42Å; I67-S371 WeakPolarHBondContact CG2-O 3.45Å; I67-S371 WeakPolarHBondContact CG2-OG 3.18Å; A367-S371 WeakPolarHBondContact O-CB 3.18Å; A367-S371 PolarHBondContact O-N 3.45Å; A367-S371 PolarHBondContact O-OG 3.49Å; A368-S371 PolarHBondContact O-N 2.88Å; A368-S371 PolarHBondContact O-OG 2.99Å; S371-T373 PolarHBondContact O-N 3.38Å; S371-T375 PolarHBondContact O-N 2.81Å; S371-T375 PolarHBondContact O-OG1 3.5Å
372	S	87.3	Confident	89.2	Confident	1 Å²	1	10.1 Å²	10.1	1%	0.007	5%	0.053	C	C	.	.	H	α-helix	trans	-68.2	-31.4	-179.3	-165.1	0	0	0	0	113.3	E149 A368 M374 T375 G376	E149-S372 VanDerWaalsContact OE1-C 3.28Å; E149-S372 WeakPolarHBondContact OE1-CB 3.32Å; A368-S372 PolarHBondContact O-N 3.32Å; A368-S372 VanDerWaalsContact O-N 3.1Å; S372-M374 PolarHBondContact O-N 3.45Å; S372-T375 CarbonylContact O-C 3.08Å; S372-T375 WeakPolarHBondContact O-CA 3.5Å; S372-T375 WeakPolarHBondContact O-CB 3.36Å; S372-T375 PolarHBondContact O-N 2.89Å; S372-G376 PolarHBondContact O-N 2.87Å
373	T	84.5	Confident	88.9	Confident	2 Å²	2	10.1 Å²	10.1	1%	0.012	5%	0.053	C	C	.	.	H	α-helix	trans	-73.2	-41.4	-170.9	15.8	0	0	0	0	110.1	E149 G369 Q370 S371 T375 T377 R402	E149-T373 WeakPolarHBondContact OE1-CA 3.34Å; E149-T373 WeakPolarHBondContact OE1-CB 3.41Å; E149-T373 PolarHBondContact OE1-N 3.47Å; E149-T373 PolarHBondContact OE1-OG1 2.91Å; E149-T373 WeakPolarHBondContact OE2-CA 3.44Å; E149-T373 WeakPolarHBondContact OE2-CB 3.23Å; E149-T373 PolarHBondContact OE2-N 3.02Å; G369-T373 PolarHBondContact O-OG1 2.92Å; Q370-T373 PolarHBondContact O-OG1 3.21Å; S371-T373 PolarHBondContact O-N 3.38Å; T373-T375 VanDerWaalsContact C-N 3.27Å; T373-T375 PolarHBondContact O-N 2.93Å; T373-T377 WeakPolarHBondContact O-CB 3.35Å; T373-T377 VanDerWaalsContact O-CG2 3.24Å; T373-T377 WeakPolarHBondContact O-CG2 3.36Å; T373-T377 PolarHBondContact O-N 2.72Å; T373-T377 PolarHBondContact O-OG1 3.21Å; T373-R402 VanDerWaalsContact CB-NH1 3.29Å
374	M	82.9	Confident	88.5	Confident	6 Å²	6	7.3 Å²	7.3	3%	0.03	4%	0.039	C	C	.	.	H	α-helix	trans	-60.7	-42.4	171	-52	-175.4	54.2	0	0	110.4	F181 L192 F195 F196 S372 T377 Y378	F181-M374 HydrophobicContact CB-CG 4.44Å; F181-M374 HydrophobicContact CD2-CB 3.76Å; F181-M374 HydrophobicContact CD2-CE 3.6Å; F181-M374 HydrophobicContact CD2-CG 3.33Å; F181-M374 HydrophobicContact CD2-SD 3.99Å; F181-M374 HydrophobicContact CE2-CB 3.59Å; F181-M374 HydrophobicContact CE2-CE 3.71Å; F181-M374 HydrophobicContact CE2-CG 3.73Å; F181-M374 HydrophobicContact CE2-SD 4.47Å; F181-M374 HydrophobicContact CG-CG 4.07Å; F181-M374 HydrophobicContact CZ-CB 4.37Å; L192-M374 HydrophobicContact CD1-CE 3.88Å; L192-M374 HydrophobicContact CD2-CE 3.37Å; L192-M374 HydrophobicContact CG-CE 3.71Å; F195-M374 HydrophobicContact CD1-CE 4.18Å; F195-M374 HydrophobicContact CD1-SD 4.05Å; F195-M374 HydrophobicContact CE1-CE 4.39Å; F195-M374 HydrophobicContact CE1-SD 3.72Å; F196-M374 HydrophobicContact CD1-SD 4.38Å; F196-M374 HydrophobicContact CE1-CB 3.71Å; F196-M374 HydrophobicContact CE1-CE 3.83Å; F196-M374 HydrophobicContact CE1-CG 4.12Å; F196-M374 HydrophobicContact CE1-SD 3.57Å; F196-M374 VanDerWaalsContact CE1-SD 3.57Å; F196-M374 HydrophobicContact CE2-CE 4.06Å; F196-M374 HydrophobicContact CZ-CB 3.44Å; F196-M374 VanDerWaalsContact CZ-CB 3.44Å; F196-M374 HydrophobicContact CZ-CE 3.54Å; F196-M374 HydrophobicContact CZ-CG 4.2Å; F196-M374 HydrophobicContact CZ-SD 3.86Å; S372-M374 PolarHBondContact O-N 3.45Å; M374-T377 WeakPolarHBondContact CA-OG1 3.05Å; M374-T377 PolarHBondContact O-OG1 2.9Å; M374-Y378 WeakPolarHBondContact O-CD2 3.23Å; M374-Y378 PolarHBondContact O-N 3.36Å
375	T	85.3	Confident	88.1	Confident	3 Å²	3	8.8 Å²	8.8	2%	0.018	5%	0.045	C	C	.	.	H	α-helix	trans	-67.1	-46.3	-179	-55.1	0	0	0	0	111.9	A68 L256 S371 S372 T373 T377 Y378 A379	A68-T375 HydrophobicContact CB-CG2 4.16Å; L256-T375 HydrophobicContact CD2-CG2 3.25Å; S371-T375 PolarHBondContact O-N 2.81Å; S371-T375 PolarHBondContact O-OG1 3.5Å; S372-T375 CarbonylContact O-C 3.08Å; S372-T375 WeakPolarHBondContact O-CA 3.5Å; S372-T375 WeakPolarHBondContact O-CB 3.36Å; S372-T375 PolarHBondContact O-N 2.89Å; T373-T375 VanDerWaalsContact C-N 3.27Å; T373-T375 PolarHBondContact O-N 2.93Å; T375-T377 PolarHBondContact O-N 3.36Å; T375-Y378 PolarHBondContact O-N 3.33Å; T375-A379 WeakPolarHBondContact O-CB 3.44Å; T375-A379 PolarHBondContact O-N 3.43Å
376	G	85.6	Confident	87.7	Confident	4 Å²	4	8.8 Å²	8.8	4%	0.041	5%	0.046	C	C	.	.	H	α-helix	trans	-64.2	-37.9	178.2	0	0	0	0	0	112.9	S372 A379 G380	S372-G376 PolarHBondContact O-N 2.87Å; G376-A379 PolarHBondContact O-N 2.95Å; G376-G380 PolarHBondContact O-N 2.84Å
377	T	83.4	Confident	87.4	Confident	6 Å²	6	6.9 Å²	6.9	4%	0.037	4%	0.036	C	C	.	.	H	α-helix	trans	-68.2	-38	176.4	52.5	0	0	0	0	112.8	F181 T373 M374 T375 Q381 V398	F181-T377 HydrophobicContact CE1-CG2 4.29Å; F181-T377 WeakPolarHBondContact CE1-OG1 3.45Å; F181-T377 VanDerWaalsContact CZ-OG1 3.29Å; F181-T377 WeakPolarHBondContact CZ-OG1 3.36Å; T373-T377 WeakPolarHBondContact O-CB 3.35Å; T373-T377 VanDerWaalsContact O-CG2 3.24Å; T373-T377 WeakPolarHBondContact O-CG2 3.36Å; T373-T377 PolarHBondContact O-N 2.72Å; T373-T377 PolarHBondContact O-OG1 3.21Å; M374-T377 WeakPolarHBondContact CA-OG1 3.05Å; M374-T377 PolarHBondContact O-OG1 2.9Å; T375-T377 PolarHBondContact O-N 3.36Å; T377-Q381 PolarHBondContact O-N 3.14Å; T377-V398 HydrophobicContact CG2-CB 4.41Å; T377-V398 HydrophobicContact CG2-CG1 3.97Å; T377-V398 HydrophobicContact CG2-CG2 3.86Å
378	Y	84.3	Confident	86.9	Confident	5 Å²	5	8.7 Å²	8.7	2%	0.02	4%	0.044	C	C	.	.	H	α-helix	trans	-67.3	-40.5	170.2	-70.3	-56	0	0	0	112	Y35 F181 D185 L192 M374 T375 G380 Q381 F382	Y35-Y378 HydrophobicContact CD1-CD1 4.46Å; Y35-Y378 HydrophobicContact CD1-CE1 4.07Å; Y35-Y378 HydrophobicContact CD2-CD1 4.41Å; Y35-Y378 AromaticContact CD2-CE1 3.37Å; Y35-Y378 HydrophobicContact CD2-CE1 3.37Å; Y35-Y378 AromaticContact CD2-CZ 3.54Å; Y35-Y378 WeakPolarHBondContact CD2-OH 3.36Å; Y35-Y378 HydrophobicContact CE1-CE1 4.19Å; Y35-Y378 HydrophobicContact CE1-CE2 4.23Å; Y35-Y378 AromaticContact CE1-CZ 3.98Å; Y35-Y378 AromaticContact CE2-CE1 3.56Å; Y35-Y378 HydrophobicContact CE2-CE1 3.56Å; Y35-Y378 HydrophobicContact CE2-CE2 4.04Å; Y35-Y378 AromaticContact CE2-CZ 3.17Å; Y35-Y378 WeakPolarHBondContact CE2-OH 3.01Å; Y35-Y378 HydrophobicContact CG-CD1 4.27Å; Y35-Y378 AromaticContact CG-CE1 3.62Å; Y35-Y378 HydrophobicContact CG-CE1 3.62Å; Y35-Y378 AromaticContact CZ-CE1 3.91Å; Y35-Y378 AromaticContact CZ-CE2 3.75Å; Y35-Y378 AromaticContact CZ-CZ 3.35Å; Y35-Y378 VanDerWaalsContact CZ-OH 3.29Å; Y35-Y378 PolarHBondContact OH-OH 3.11Å; F181-Y378 AromaticContact CE2-CE2 3.75Å; F181-Y378 HydrophobicContact CE2-CE2 3.75Å; F181-Y378 AromaticContact CE2-CZ 3.72Å; F181-Y378 VanDerWaalsContact CE2-OH 3.25Å; F181-Y378 WeakPolarHBondContact CE2-OH 3.35Å; F181-Y378 HydrophobicContact CZ-CD2 4.44Å; F181-Y378 HydrophobicContact CZ-CE1 4.11Å; F181-Y378 AromaticContact CZ-CE2 3.74Å; F181-Y378 HydrophobicContact CZ-CE2 3.74Å; F181-Y378 AromaticContact CZ-CZ 3.5Å; F181-Y378 VanDerWaalsContact CZ-CZ 3.5Å; F181-Y378 WeakPolarHBondContact CZ-OH 3.29Å; D185-Y378 PolarHBondContact OD1-OH 2.93Å; L192-Y378 WeakPolarHBondContact CD1-OH 3.35Å; M374-Y378 WeakPolarHBondContact O-CD2 3.23Å; M374-Y378 PolarHBondContact O-N 3.36Å; T375-Y378 PolarHBondContact O-N 3.33Å; Y378-G380 PolarHBondContact O-N 2.75Å; Y378-Q381 VanDerWaalsContact O-CB 3.32Å; Y378-Q381 WeakPolarHBondContact O-CB 3.43Å; Y378-Q381 PolarHBondContact O-N 3.07Å; Y378-F382 WeakPolarHBondContact O-CD2 3.3Å; Y378-F382 PolarHBondContact O-N 2.92Å; Y378-F382 VanDerWaalsContact O-N 3.09Å
379	A	88.4	Confident	86.4	Confident	0 Å²	0	14 Å²	14	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-61.4	-46.8	177.4	0	0	0	0	0	111.1	I142 H252 L256 T375 G376 Q381 F382 V383	I142-A379 HydrophobicContact CD1-CB 4.27Å; I142-A379 HydrophobicContact CG1-CB 4.37Å; H252-A379 HydrophobicContact CB-CB 4.11Å; L256-A379 HydrophobicContact CB-CB 4.17Å; T375-A379 WeakPolarHBondContact O-CB 3.44Å; T375-A379 PolarHBondContact O-N 3.43Å; G376-A379 PolarHBondContact O-N 2.95Å; A379-Q381 VanDerWaalsContact C-N 3.28Å; A379-Q381 PolarHBondContact O-N 2.88Å; A379-F382 PolarHBondContact O-N 3.33Å; A379-V383 WeakPolarHBondContact O-CB 3.35Å; A379-V383 WeakPolarHBondContact O-CG2 3.48Å; A379-V383 PolarHBondContact O-N 2.84Å
380	G	87.3	Confident	85.7	Confident	1 Å²	1	18 Å²	18	1%	0.01	9%	0.086	C	C	.	.	H	α-helix	trans	-61.5	-34.9	174.8	0	0	0	0	0	113.1	G376 Y378 M384	G376-G380 PolarHBondContact O-N 2.84Å; Y378-G380 PolarHBondContact O-N 2.75Å; G380-M384 WeakPolarHBondContact O-CB 3.45Å; G380-M384 VanDerWaalsContact O-CG 3.31Å; G380-M384 WeakPolarHBondContact O-CG 3.1Å; G380-M384 PolarHBondContact O-N 3.28Å
381	Q	85.1	Confident	84.8	Confident	12 Å²	12	25.3 Å²	25.3	6%	0.056	11%	0.111	C	C	.	.	H	α-helix	trans	-57	-60.2	171.7	170.7	155.5	8.7	0	0	112.3	T377 Y378 A379 V383 M384 E385 R397	T377-Q381 PolarHBondContact O-N 3.14Å; Y378-Q381 VanDerWaalsContact O-CB 3.32Å; Y378-Q381 WeakPolarHBondContact O-CB 3.43Å; Y378-Q381 PolarHBondContact O-N 3.07Å; A379-Q381 VanDerWaalsContact C-N 3.28Å; A379-Q381 PolarHBondContact O-N 2.88Å; Q381-V383 VanDerWaalsContact C-N 3.27Å; Q381-V383 PolarHBondContact O-N 3.17Å; Q381-M384 PolarHBondContact O-N 2.81Å; Q381-E385 WeakPolarHBondContact CG-OE1 3.5Å; Q381-E385 WeakPolarHBondContact CG-OE2 3.39Å; Q381-E385 PolarHBondContact NE2-OE1 3.47Å; Q381-E385 PolarHBondContact NE2-OE2 2.89Å; Q381-E385 WeakPolarHBondContact O-CB 3.48Å; Q381-E385 PolarHBondContact O-N 3.35Å; Q381-R397 VanDerWaalsContact CB-NH2 3.26Å; Q381-R397 VanDerWaalsContact CG-CZ 3.43Å; Q381-R397 VanDerWaalsContact CG-NH1 3.32Å; Q381-R397 VanDerWaalsContact CG-NH2 3.28Å
382	F	87	Confident	83.9	Confident	7 Å²	7	30.8 Å²	30.8	3%	0.031	13%	0.132	C	C	.	.	H	α-helix	trans	-67.4	-32.8	-173.4	-63.7	-56.2	0	0	0	111.8	L36 L256 A259 L260 Y378 A379 G386	L36-F382 HydrophobicContact CD1-CE1 3.58Å; L36-F382 HydrophobicContact CD1-CZ 4.22Å; L36-F382 HydrophobicContact CG-CE1 4.19Å; L36-F382 HydrophobicContact CG-CZ 4.39Å; L256-F382 HydrophobicContact CD1-CD2 3.76Å; L256-F382 HydrophobicContact CD1-CE2 3.83Å; A259-F382 HydrophobicContact CB-CB 3.85Å; A259-F382 HydrophobicContact CB-CD1 3.59Å; A259-F382 HydrophobicContact CB-CD2 3.44Å; A259-F382 VanDerWaalsContact CB-CD2 3.44Å; A259-F382 HydrophobicContact CB-CE1 3.95Å; A259-F382 HydrophobicContact CB-CE2 3.8Å; A259-F382 HydrophobicContact CB-CG 3.32Å; A259-F382 HydrophobicContact CB-CZ 4.04Å; L260-F382 HydrophobicContact CD2-CE2 4.47Å; Y378-F382 WeakPolarHBondContact O-CD2 3.3Å; Y378-F382 PolarHBondContact O-N 2.92Å; Y378-F382 VanDerWaalsContact O-N 3.09Å; A379-F382 PolarHBondContact O-N 3.33Å; F382-G386 WeakPolarHBondContact O-CA 3.36Å; F382-G386 PolarHBondContact O-N 3.39Å
383	V	89.5	Confident	83.2	Confident	0 Å²	0	34 Å²	34	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-67.3	-49.3	175.8	169.3	0	0	0	0	110.9	I138 I142 Y255 A379 Q381 F387	I138-V383 HydrophobicContact CB-CG1 4.13Å; I138-V383 HydrophobicContact CG2-CB 4.34Å; I138-V383 HydrophobicContact CG2-CG1 3.81Å; I138-V383 HydrophobicContact CG2-CG2 3.62Å; I142-V383 HydrophobicContact CD1-CB 4.24Å; I142-V383 HydrophobicContact CD1-CG1 4.49Å; I142-V383 HydrophobicContact CD1-CG2 4.13Å; Y255-V383 HydrophobicContact CD1-CG2 4.36Å; Y255-V383 HydrophobicContact CG-CG2 4.04Å; A379-V383 WeakPolarHBondContact O-CB 3.35Å; A379-V383 WeakPolarHBondContact O-CG2 3.48Å; A379-V383 PolarHBondContact O-N 2.84Å; Q381-V383 VanDerWaalsContact C-N 3.27Å; Q381-V383 PolarHBondContact O-N 3.17Å; V383-F387 HydrophobicContact CG1-CD2 3.91Å; V383-F387 HydrophobicContact CG1-CE2 4.29Å; V383-F387 VanDerWaalsContact O-CB 3.31Å; V383-F387 WeakPolarHBondContact O-CB 3.5Å; V383-F387 WeakPolarHBondContact O-CD2 3.25Å; V383-F387 PolarHBondContact O-N 3.47Å
384	M	86.7	Confident	82.6	Confident	19 Å²	19	36.2 Å²	36.2	9%	0.094	16%	0.162	C	C	.	.	H	α-helix	trans	-62.4	-47.8	177.6	-74.1	-170.1	149.3	0	0	112.8	W135 E139 G380 Q381 L388 R389 R397	W135-M384 HydrophobicContact CZ2-CE 4.13Å; E139-M384 WeakPolarHBondContact OE1-CG 3.33Å; G380-M384 WeakPolarHBondContact O-CB 3.45Å; G380-M384 VanDerWaalsContact O-CG 3.31Å; G380-M384 WeakPolarHBondContact O-CG 3.1Å; G380-M384 PolarHBondContact O-N 3.28Å; Q381-M384 PolarHBondContact O-N 2.81Å; M384-L388 WeakPolarHBondContact O-CB 3.35Å; M384-L388 PolarHBondContact O-N 2.93Å; M384-R389 PolarHBondContact O-N 3.36Å; M384-R397 VanDerWaalsContact SD-CD 3.57Å; M384-R397 HydrophobicContact SD-CG 3.76Å
385	E	86.7	Confident	82.2	Confident	31 Å²	31	41.5 Å²	41.5	15%	0.145	19%	0.185	C	C	.	.	H	α-helix	trans	-67.6	-41.3	-178.1	-75.3	164.8	-162	0	0	111	Q381 R389 R397	Q381-E385 WeakPolarHBondContact CG-OE1 3.5Å; Q381-E385 WeakPolarHBondContact CG-OE2 3.39Å; Q381-E385 PolarHBondContact NE2-OE1 3.47Å; Q381-E385 PolarHBondContact NE2-OE2 2.89Å; Q381-E385 WeakPolarHBondContact O-CB 3.48Å; Q381-E385 PolarHBondContact O-N 3.35Å; E385-R389 WeakPolarHBondContact O-CA 3.41Å; E385-R389 PolarHBondContact O-N 2.83Å; E385-R397 IonicContact OE1-CZ 2.73Å; E385-R397 IonicContact OE1-NH1 3.45Å; E385-R397 PolarHBondContact OE1-NH1 3.49Å
386	G	85.5	Confident	81.9	Confident	1 Å²	1	43.3 Å²	43.3	1%	0.01	20%	0.201	C	C	.	.	H	α-helix	trans	-68.1	-52.3	178.3	0	0	0	0	0	112.8	G119 H123 F382	G119-G386 CarbonylContact O-C 3.51Å; H123-G386 VanDerWaalsContact CB-O 3.26Å; H123-G386 WeakPolarHBondContact CB-O 3.45Å; F382-G386 WeakPolarHBondContact O-CA 3.36Å; F382-G386 PolarHBondContact O-N 3.39Å
387	F	87.3	Confident	81.5	Confident	0 Å²	0	43.4 Å²	43.4	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-76.3	-41.7	-174.7	-83.5	-87.7	0	0	0	114.2	C122 H123 R131 L134 W135 Y255 V383	C122-F387 HydrophobicContact CB-CD1 4.25Å; C122-F387 HydrophobicContact CB-CE1 3.52Å; C122-F387 HydrophobicContact CB-CZ 3.73Å; H123-F387 PolarHBondContact ND1-O 3.44Å; R131-F387 HydrophobicContact CG-CD1 3.86Å; L134-F387 HydrophobicContact CB-CE1 4.01Å; L134-F387 HydrophobicContact CD2-CE1 3.63Å; L134-F387 HydrophobicContact CD2-CZ 3.73Å; L134-F387 HydrophobicContact CG-CE1 3.62Å; L134-F387 HydrophobicContact CG-CZ 3.67Å; W135-F387 HydrophobicContact CB-CB 3.83Å; W135-F387 HydrophobicContact CB-CD1 3.94Å; W135-F387 HydrophobicContact CB-CG 3.86Å; W135-F387 HydrophobicContact CG-CB 4.02Å; W135-F387 HydrophobicContact CG-CG 4.42Å; Y255-F387 AromaticContact CD1-CE2 3.99Å; Y255-F387 HydrophobicContact CD1-CE2 3.99Å; Y255-F387 AromaticContact CE1-CE2 3.4Å; Y255-F387 HydrophobicContact CE1-CE2 3.4Å; Y255-F387 VanDerWaalsContact CE1-CE2 3.4Å; Y255-F387 AromaticContact CE1-CZ 3.64Å; Y255-F387 HydrophobicContact CE1-CZ 3.64Å; Y255-F387 AromaticContact CZ-CE2 3.98Å; Y255-F387 AromaticContact CZ-CZ 3.94Å; V383-F387 HydrophobicContact CG1-CD2 3.91Å; V383-F387 HydrophobicContact CG1-CE2 4.29Å; V383-F387 VanDerWaalsContact O-CB 3.31Å; V383-F387 WeakPolarHBondContact O-CB 3.5Å; V383-F387 WeakPolarHBondContact O-CD2 3.25Å; V383-F387 PolarHBondContact O-N 3.47Å
388	L	83.3	Confident	81.2	Confident	45 Å²	45	43.4 Å²	43.4	24%	0.236	20%	0.2	C	C	.	.	H	α-helix	trans	-109.3	-11.7	-171.7	-61.5	-176.9	0	0	0	113.5	T132 W135 M384 L390	T132-L388 HydrophobicContact CG2-CD2 4.46Å; W135-L388 HydrophobicContact CD2-CD1 3.58Å; W135-L388 HydrophobicContact CD2-CD2 4.34Å; W135-L388 HydrophobicContact CD2-CG 3.99Å; W135-L388 HydrophobicContact CE3-CD1 3.9Å; W135-L388 HydrophobicContact CE3-CD2 4.5Å; W135-L388 HydrophobicContact CG-CD1 4.2Å; W135-L388 HydrophobicContact CG-CD2 4.44Å; W135-L388 HydrophobicContact CG-CG 4.09Å; W135-L388 HydrophobicContact CH2-CD1 3.82Å; W135-L388 HydrophobicContact CZ2-CD1 3.5Å; W135-L388 VanDerWaalsContact CZ2-CD1 3.5Å; W135-L388 HydrophobicContact CZ3-CD1 4.01Å; M384-L388 WeakPolarHBondContact O-CB 3.35Å; M384-L388 PolarHBondContact O-N 2.93Å; L388-L390 HydrophobicContact CB-CB 4.28Å; L388-L390 HydrophobicContact CB-CD1 3.79Å; L388-L390 HydrophobicContact CB-CG 3.79Å; L388-L390 HydrophobicContact CD1-CD1 3.65Å; L388-L390 HydrophobicContact CG-CD1 4.39Å; L388-L390 PolarHBondContact O-N 2.98Å; L388-L390 VanDerWaalsContact O-N 3.14Å
389	R	82.9	Confident	81.1	Confident	111 Å²	111	47.6 Å²	47.6	42%	0.419	22%	0.222	S	C	.	.			trans	53.8	25.9	-171.6	-56.9	-178.2	-175.4	-168.1	-5.3	113	H123 M384 E385 R391 E544	H123-R389 VanDerWaalsContact CD2-CZ 3.49Å; H123-R389 PolarHBondContact CD2-NE 2.65Å; H123-R389 VanDerWaalsContact CD2-NE 3.3Å; H123-R389 PolarHBondContact CD2-NH2 2.88Å; H123-R389 PolarHBondContact NE2-NE 3.1Å; M384-R389 PolarHBondContact O-N 3.36Å; E385-R389 WeakPolarHBondContact O-CA 3.41Å; E385-R389 PolarHBondContact O-N 2.83Å; R389-R391 PolarHBondContact O-N 3.34Å; R389-E544 IonicContact CZ-OE1 2.76Å; R389-E544 IonicContact NH1-OE1 2.72Å; R389-E544 PolarHBondContact NH1-OE1 3.19Å; R389-E544 IonicContact NH2-OE1 3.33Å; R389-E544 PolarHBondContact NH2-OE1 3.3Å
390	L	77.3	Confident	80.9	Confident	85 Å²	85	51.1 Å²	51.1	45%	0.445	24%	0.241	S	C	.	.			trans	-83.9	112	176.6	-72.5	173.1	0	0	0	108.8	L388 W392	L388-L390 HydrophobicContact CB-CB 4.28Å; L388-L390 HydrophobicContact CB-CD1 3.79Å; L388-L390 HydrophobicContact CB-CG 3.79Å; L388-L390 HydrophobicContact CD1-CD1 3.65Å; L388-L390 HydrophobicContact CG-CD1 4.39Å; L388-L390 PolarHBondContact O-N 2.98Å; L388-L390 VanDerWaalsContact O-N 3.14Å; L390-W392 PolarHBondContact O-N 2.91Å
391	R	70.8	Confident	80.5	Confident	193 Å²	193	51.6 Å²	51.6	73%	0.728	24%	0.243	S	C	*	.			trans	-90.9	92.8	173.4	-66.3	-173.9	178.5	170.1	0.8	109.5	R389	R389-R391 PolarHBondContact O-N 3.34Å
392	W	70.6	Confident	80.4	Confident	114 Å²	114	51.2 Å²	51.2	43%	0.432	24%	0.242	S	C	.	.			trans	-89.9	157.9	172.8	-87.4	21.7	0	0	0	111.6	L390 A396 R397 L400	L390-W392 PolarHBondContact O-N 2.91Å; W392-A396 HydrophobicContact CE3-CB 4.36Å; W392-R397 HydrophobicContact CE3-CB 4.35Å; W392-L400 HydrophobicContact CH2-CD2 3.71Å; W392-L400 HydrophobicContact CZ3-CB 4.22Å; W392-L400 HydrophobicContact CZ3-CD2 3.46Å; W392-L400 VanDerWaalsContact CZ3-CD2 3.46Å; W392-L400 HydrophobicContact CZ3-CG 4.41Å
393	S	74	Confident	80.3	Confident	68 Å²	68	53.8 Å²	53.8	48%	0.476	26%	0.26	S	S	.	.			trans	-65.1	138.7	168.1	74.8	0	0	0	0	109.3	F395 A396 R397	S393-F395 PolarHBondContact O-N 2.78Å; S393-A396 PolarHBondContact O-N 3.45Å; S393-A396 VanDerWaalsContact OG-CB 3.25Å; S393-A396 WeakPolarHBondContact OG-CB 3.43Å; S393-A396 PolarHBondContact OG-N 3.06Å; S393-R397 PolarHBondContact O-N 3.23Å; S393-R397 VanDerWaalsContact O-N 3.17Å
394	R	69.9	Low	80.2	Confident	49 Å²	49	56.8 Å²	56.8	19%	0.185	28%	0.28	C	S	.	.	H	α-helix	trans	-50.7	-44.7	-179	-69.2	-177	-79.1	156.3	-4	112	R32 T34 D185 R397 V398	R32-R394 PolarHBondContact O-NE 3.47Å; R32-R394 PolarHBondContact O-NH2 3.09Å; T34-R394 PolarHBondContact OG1-NH1 3.25Å; T34-R394 PolarHBondContact OG1-NH2 2.68Å; D185-R394 IonicContact OD2-CZ 2.89Å; D185-R394 IonicContact OD2-NH1 2.97Å; D185-R394 PolarHBondContact OD2-NH1 3.22Å; R394-R397 PolarHBondContact O-N 3.28Å; R394-V398 WeakPolarHBondContact O-CG2 3.25Å; R394-V398 PolarHBondContact O-N 2.9Å; R394-V398 VanDerWaalsContact O-N 3.08Å
395	F	75.1	Confident	80	Confident	117 Å²	117	55.9 Å²	55.9	51%	0.513	28%	0.276	S	S	.	.	H	α-helix	trans	-61	-46.5	177.9	-75.3	-93.7	0	0	0	113	L182 S393 R397 L399	L182-F395 HydrophobicContact CB-CE1 4.1Å; L182-F395 HydrophobicContact CB-CZ 4.27Å; L182-F395 HydrophobicContact CD1-CD1 3.61Å; L182-F395 HydrophobicContact CD1-CE1 3.68Å; L182-F395 HydrophobicContact CD1-CG 4.39Å; L182-F395 HydrophobicContact CD2-CD1 4.44Å; L182-F395 HydrophobicContact CD2-CE1 4.43Å; L182-F395 HydrophobicContact CG-CD1 4.5Å; L182-F395 HydrophobicContact CG-CE1 4.29Å; S393-F395 PolarHBondContact O-N 2.78Å; F395-R397 VanDerWaalsContact C-N 3.33Å; F395-R397 PolarHBondContact O-N 2.9Å; F395-L399 WeakPolarHBondContact O-CB 3.3Å; F395-L399 PolarHBondContact O-N 3.03Å
396	A	79.4	Confident	80	Confident	42 Å²	42	55.1 Å²	55.1	35%	0.347	27%	0.273	S	S	.	.	H	α-helix	trans	-65.2	-38.8	-178	0	0	0	0	0	111.9	W392 S393 L400	W392-A396 HydrophobicContact CE3-CB 4.36Å; S393-A396 PolarHBondContact O-N 3.45Å; S393-A396 VanDerWaalsContact OG-CB 3.25Å; S393-A396 WeakPolarHBondContact OG-CB 3.43Å; S393-A396 PolarHBondContact OG-N 3.06Å; A396-L400 VanDerWaalsContact O-CB 3.31Å; A396-L400 WeakPolarHBondContact O-CB 3.46Å; A396-L400 PolarHBondContact O-N 2.77Å
397	R	77.4	Confident	80.1	Confident	6 Å²	6	60.8 Å²	60.8	2%	0.023	30%	0.302	C	S	.	.	H	α-helix	trans	-68.5	-49.5	178.8	-179.6	177.7	59.6	-138	-8.6	112.4	Q381 M384 E385 W392 S393 R394 F395 L399 L400 T401	Q381-R397 VanDerWaalsContact CB-NH2 3.26Å; Q381-R397 VanDerWaalsContact CG-CZ 3.43Å; Q381-R397 VanDerWaalsContact CG-NH1 3.32Å; Q381-R397 VanDerWaalsContact CG-NH2 3.28Å; M384-R397 VanDerWaalsContact SD-CD 3.57Å; M384-R397 HydrophobicContact SD-CG 3.76Å; E385-R397 IonicContact OE1-CZ 2.73Å; E385-R397 IonicContact OE1-NH1 3.45Å; E385-R397 PolarHBondContact OE1-NH1 3.49Å; W392-R397 HydrophobicContact CE3-CB 4.35Å; S393-R397 PolarHBondContact O-N 3.23Å; S393-R397 VanDerWaalsContact O-N 3.17Å; R394-R397 PolarHBondContact O-N 3.28Å; F395-R397 VanDerWaalsContact C-N 3.33Å; F395-R397 PolarHBondContact O-N 2.9Å; R397-L399 VanDerWaalsContact C-N 3.3Å; R397-L399 PolarHBondContact O-N 2.99Å; R397-L400 PolarHBondContact O-N 3.49Å; R397-T401 PolarHBondContact O-N 3.19Å; R397-T401 PolarHBondContact O-OG1 3.11Å
398	V	77.7	Confident	79.9	Confident	6 Å²	6	62.8 Å²	62.8	4%	0.036	32%	0.315	C	S	.	.	H	α-helix	trans	-60.3	-45	178	172.8	0	0	0	0	109.7	L182 T377 R394 L400 T401 R402	L182-V398 HydrophobicContact CD1-CG1 4.4Å; L182-V398 HydrophobicContact CD2-CB 4.49Å; L182-V398 HydrophobicContact CD2-CG2 4.19Å; T377-V398 HydrophobicContact CG2-CB 4.41Å; T377-V398 HydrophobicContact CG2-CG1 3.97Å; T377-V398 HydrophobicContact CG2-CG2 3.86Å; R394-V398 WeakPolarHBondContact O-CG2 3.25Å; R394-V398 PolarHBondContact O-N 2.9Å; R394-V398 VanDerWaalsContact O-N 3.08Å; V398-L400 PolarHBondContact O-N 3.05Å; V398-T401 PolarHBondContact O-OG1 3.42Å; V398-T401 VanDerWaalsContact O-OG1 3.12Å; V398-R402 HydrophobicContact CG1-CG 4.14Å; V398-R402 WeakPolarHBondContact O-CB 3.27Å; V398-R402 WeakPolarHBondContact O-CG 3.47Å; V398-R402 PolarHBondContact O-N 2.9Å
399	L	81.2	Confident	79.9	Confident	93 Å²	93	60.7 Å²	60.7	49%	0.487	30%	0.304	S	S	.	.	H	α-helix	trans	-63.5	-40.8	178.5	-169.1	70.4	0	0	0	112.1	F395 R397 S403	F395-L399 WeakPolarHBondContact O-CB 3.3Å; F395-L399 PolarHBondContact O-N 3.03Å; R397-L399 VanDerWaalsContact C-N 3.3Å; R397-L399 PolarHBondContact O-N 2.99Å; L399-S403 WeakPolarHBondContact O-CB 3.37Å; L399-S403 PolarHBondContact O-N 3.47Å; L399-S403 PolarHBondContact O-OG 3.12Å
400	L	84.3	Confident	80	Confident	74 Å²	74	57.1 Å²	57.1	39%	0.387	30%	0.295	S	S	.	.	H	α-helix	trans	-63.8	-55.7	177.7	179.7	71.4	0	0	0	111.5	W392 A396 R397 V398 R402 S403 C404	W392-L400 HydrophobicContact CH2-CD2 3.71Å; W392-L400 HydrophobicContact CZ3-CB 4.22Å; W392-L400 HydrophobicContact CZ3-CD2 3.46Å; W392-L400 VanDerWaalsContact CZ3-CD2 3.46Å; W392-L400 HydrophobicContact CZ3-CG 4.41Å; A396-L400 VanDerWaalsContact O-CB 3.31Å; A396-L400 WeakPolarHBondContact O-CB 3.46Å; A396-L400 PolarHBondContact O-N 2.77Å; R397-L400 PolarHBondContact O-N 3.49Å; V398-L400 PolarHBondContact O-N 3.05Å; L400-R402 VanDerWaalsContact C-N 3.31Å; L400-R402 PolarHBondContact O-N 3.41Å; L400-S403 WeakPolarHBondContact O-CB 3.27Å; L400-S403 PolarHBondContact O-N 2.82Å; L400-S403 VanDerWaalsContact O-N 3.13Å; L400-C404 PolarHBondContact O-N 3.07Å; L400-C404 PolarHBondContact O-SG 3.41Å; L400-C404 VanDerWaalsContact O-SG 3.4Å
401	T	78.2	Confident	80.3	Confident	10 Å²	10	57.1 Å²	57.1	6%	0.061	30%	0.295	C	S	.	.	H	α-helix	trans	-58.9	-44.6	-177.6	47	0	0	0	0	111.1	R397 V398 S403 C404 A405	R397-T401 PolarHBondContact O-N 3.19Å; R397-T401 PolarHBondContact O-OG1 3.11Å; V398-T401 PolarHBondContact O-OG1 3.42Å; V398-T401 VanDerWaalsContact O-OG1 3.12Å; T401-S403 PolarHBondContact O-N 3.02Å; T401-C404 WeakPolarHBondContact O-CB 3.46Å; T401-C404 PolarHBondContact O-N 3.27Å; T401-A405 PolarHBondContact O-N 3.43Å; T401-A405 VanDerWaalsContact O-N 3.09Å
402	R	84	Confident	80.7	Confident	5 Å²	5	49.7 Å²	49.7	2%	0.019	27%	0.271	C	S	.	.	H	α-helix	trans	-65.3	-39	174.8	-68.5	-73.7	128.4	161.3	2.9	112.8	D146 E149 T178 T373 V398 L400 C404 A405 I406	D146-R402 IonicContact OD1-CZ 2.77Å; D146-R402 IonicContact OD1-NE 2.67Å; D146-R402 PolarHBondContact OD1-NE 3.32Å; D146-R402 IonicContact OD1-NH1 3.04Å; D146-R402 PolarHBondContact OD1-NH1 3Å; D146-R402 IonicContact OD1-NH2 3.64Å; D146-R402 PolarHBondContact OD1-NH2 2.97Å; D146-R402 IonicContact OD2-CZ 2.87Å; D146-R402 IonicContact OD2-NE 2.76Å; D146-R402 PolarHBondContact OD2-NE 3.31Å; D146-R402 IonicContact OD2-NH1 2.97Å; D146-R402 IonicContact OD2-NH2 3.1Å; D146-R402 PolarHBondContact OD2-NH2 3.27Å; E149-R402 IonicContact OE2-CZ 3.91Å; E149-R402 VanDerWaalsContact OE2-CZ 3.26Å; E149-R402 IonicContact OE2-NH1 3.07Å; E149-R402 PolarHBondContact OE2-NH1 3.04Å; E149-R402 IonicContact OE2-NH2 2.7Å; E149-R402 PolarHBondContact OE2-NH2 3.04Å; T178-R402 HydrophobicContact CG2-CB 4.16Å; T178-R402 HydrophobicContact CG2-CG 3.57Å; T373-R402 VanDerWaalsContact CB-NH1 3.29Å; V398-R402 HydrophobicContact CG1-CG 4.14Å; V398-R402 WeakPolarHBondContact O-CB 3.27Å; V398-R402 WeakPolarHBondContact O-CG 3.47Å; V398-R402 PolarHBondContact O-N 2.9Å; L400-R402 VanDerWaalsContact C-N 3.31Å; L400-R402 PolarHBondContact O-N 3.41Å; R402-C404 VanDerWaalsContact C-N 3.29Å; R402-C404 PolarHBondContact O-N 2.9Å; R402-A405 PolarHBondContact O-N 3.25Å; R402-I406 HydrophobicContact CB-CD1 4.2Å; R402-I406 VanDerWaalsContact O-CB 3.23Å; R402-I406 WeakPolarHBondContact O-CB 3.13Å; R402-I406 WeakPolarHBondContact O-CG1 3.2Å; R402-I406 PolarHBondContact O-N 2.99Å
403	S	85.7	Confident	81	Confident	61 Å²	61	44.9 Å²	44.9	43%	0.427	26%	0.255	S	S	.	.	H	α-helix	trans	-62.4	-40.3	174.9	-62.4	0	0	0	0	111.4	L399 L400 T401 A405 L407	L399-S403 WeakPolarHBondContact O-CB 3.37Å; L399-S403 PolarHBondContact O-N 3.47Å; L399-S403 PolarHBondContact O-OG 3.12Å; L400-S403 WeakPolarHBondContact O-CB 3.27Å; L400-S403 PolarHBondContact O-N 2.82Å; L400-S403 VanDerWaalsContact O-N 3.13Å; T401-S403 PolarHBondContact O-N 3.02Å; S403-A405 VanDerWaalsContact C-N 3.31Å; S403-A405 PolarHBondContact O-N 3.32Å; S403-L407 WeakPolarHBondContact O-CB 3.49Å; S403-L407 PolarHBondContact O-N 2.9Å
404	C	86	Confident	81.3	Confident	62 Å²	62	45.5 Å²	45.5	42%	0.419	26%	0.256	S	S	.	.	H	α-helix	trans	-65.9	-30.6	176.9	-70.7	0	0	0	0	113.2	V143 L400 T401 R402 P408	V143-C404 HydrophobicContact CG1-CB 4.39Å; V143-C404 HydrophobicContact CG2-CB 4.37Å; L400-C404 PolarHBondContact O-N 3.07Å; L400-C404 PolarHBondContact O-SG 3.41Å; L400-C404 VanDerWaalsContact O-SG 3.4Å; T401-C404 WeakPolarHBondContact O-CB 3.46Å; T401-C404 PolarHBondContact O-N 3.27Å; R402-C404 VanDerWaalsContact C-N 3.29Å; R402-C404 PolarHBondContact O-N 2.9Å; C404-P408 WeakPolarHBondContact O-CD 3.13Å; C404-P408 VanDerWaalsContact O-CG 3.25Å; C404-P408 WeakPolarHBondContact O-CG 3.44Å
405	A	83.8	Confident	81.5	Confident	0 Å²	0	50.8 Å²	50.8	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-85.7	-41.3	176.2	0	0	0	0	0	113.2	V143 D146 M147 T401 R402 S403 P408 T409	V143-A405 HydrophobicContact CG1-CB 4.35Å; D146-A405 HydrophobicContact CB-CB 3.82Å; D146-A405 VanDerWaalsContact OD1-CB 3.27Å; D146-A405 WeakPolarHBondContact OD1-CB 3.35Å; D146-A405 WeakPolarHBondContact OD2-CB 3.19Å; M147-A405 HydrophobicContact CG-CB 3.84Å; T401-A405 PolarHBondContact O-N 3.43Å; T401-A405 VanDerWaalsContact O-N 3.09Å; R402-A405 PolarHBondContact O-N 3.25Å; S403-A405 VanDerWaalsContact C-N 3.31Å; S403-A405 PolarHBondContact O-N 3.32Å; A405-P408 WeakPolarHBondContact O-CD 3.26Å; A405-P408 WeakPolarHBondContact O-CG 3.16Å; A405-T409 WeakPolarHBondContact O-CB 3.49Å; A405-T409 PolarHBondContact O-N 3.42Å; A405-T409 PolarHBondContact O-OG1 3.01Å
406	I	86.6	Confident	81.1	Confident	16 Å²	16	52.5 Å²	52.5	8%	0.082	28%	0.284	C	S	.	.	H	α-helix	trans	-71.4	-41.6	-176.8	-67.7	171.1	0	0	0	110.9	V150 V171 I175 R402 T409 V410	V150-I406 HydrophobicContact CG1-CG1 4.48Å; V150-I406 HydrophobicContact CG2-CG1 4.21Å; V171-I406 HydrophobicContact CG1-CG2 4Å; I175-I406 HydrophobicContact CG1-CD1 3.7Å; R402-I406 HydrophobicContact CB-CD1 4.2Å; R402-I406 VanDerWaalsContact O-CB 3.23Å; R402-I406 WeakPolarHBondContact O-CB 3.13Å; R402-I406 WeakPolarHBondContact O-CG1 3.2Å; R402-I406 PolarHBondContact O-N 2.99Å; I406-T409 PolarHBondContact O-N 3.22Å; I406-T409 VanDerWaalsContact O-N 3.16Å; I406-V410 HydrophobicContact CG2-CG2 3.68Å; I406-V410 WeakPolarHBondContact O-CG2 3.17Å; I406-V410 PolarHBondContact O-N 2.9Å
407	L	86.9	Confident	80.4	Confident	119 Å²	119	56.6 Å²	56.6	62%	0.623	30%	0.3	S	S	*	.	H	α-helix	trans	-54.7	-55.5	-178.3	-171.5	94.9	0	0	0	113.3	S403 T409 V410 L411	S403-L407 WeakPolarHBondContact O-CB 3.49Å; S403-L407 PolarHBondContact O-N 2.9Å; L407-T409 VanDerWaalsContact C-N 3.28Å; L407-T409 PolarHBondContact O-N 2.98Å; L407-V410 PolarHBondContact O-N 3.18Å; L407-L411 HydrophobicContact CG-CD1 4.33Å; L407-L411 VanDerWaalsContact O-CG 3.26Å; L407-L411 WeakPolarHBondContact O-CG 3.31Å; L407-L411 PolarHBondContact O-N 3.38Å
408	P	83.1	Confident	79.5	Confident	43 Å²	43	59.5 Å²	59.5	28%	0.279	32%	0.315	S	S	.	.	H	α-helix	trans	-63.4	-35.8	177.6	25.1	-33.4	0	0	0	111.8	M147 C404 A405 L411 V412	M147-P408 HydrophobicContact CE-CB 4.1Å; M147-P408 HydrophobicContact CE-CG 3.91Å; M147-P408 HydrophobicContact SD-CG 3.94Å; C404-P408 WeakPolarHBondContact O-CD 3.13Å; C404-P408 VanDerWaalsContact O-CG 3.25Å; C404-P408 WeakPolarHBondContact O-CG 3.44Å; A405-P408 WeakPolarHBondContact O-CD 3.26Å; A405-P408 WeakPolarHBondContact O-CG 3.16Å; P408-L411 PolarHBondContact O-N 2.81Å; P408-V412 WeakPolarHBondContact O-CG2 3.27Å; P408-V412 PolarHBondContact O-N 3.42Å
409	T	82.5	Confident	78.8	Confident	0 Å²	0	67.1 Å²	67.1	0%	0	34%	0.343	C	S	.	.	H	α-helix	trans	-67.8	-42.5	-179.2	-51.5	0	0	0	0	112.2	V150 I151 V171 A405 I406 L407 V412 A413 L421	V150-T409 HydrophobicContact CG1-CG2 3.92Å; I151-T409 HydrophobicContact CG1-CG2 3.73Å; V171-T409 HydrophobicContact CG1-CG2 4.28Å; V171-T409 HydrophobicContact CG2-CG2 3.94Å; A405-T409 WeakPolarHBondContact O-CB 3.49Å; A405-T409 PolarHBondContact O-N 3.42Å; A405-T409 PolarHBondContact O-OG1 3.01Å; I406-T409 PolarHBondContact O-N 3.22Å; I406-T409 VanDerWaalsContact O-N 3.16Å; L407-T409 VanDerWaalsContact C-N 3.28Å; L407-T409 PolarHBondContact O-N 2.98Å; T409-V412 PolarHBondContact O-N 3.21Å; T409-A413 VanDerWaalsContact O-CB 3.26Å; T409-A413 WeakPolarHBondContact O-CB 3.45Å; T409-A413 PolarHBondContact O-N 3.41Å; T409-L421 HydrophobicContact CG2-CD2 4.38Å
410	V	85.1	Confident	78	Confident	36 Å²	36	65.5 Å²	65.5	22%	0.218	34%	0.336	C	S	.	.	H	α-helix	trans	-64	-44.1	173.6	172.7	0	0	0	0	110.5	V171 L172 I406 L407 V412 A413 V414	V171-V410 HydrophobicContact CB-CG2 4.24Å; V171-V410 HydrophobicContact CG1-CG2 3.34Å; L172-V410 HydrophobicContact CD2-CG2 4.38Å; I406-V410 HydrophobicContact CG2-CG2 3.68Å; I406-V410 WeakPolarHBondContact O-CG2 3.17Å; I406-V410 PolarHBondContact O-N 2.9Å; L407-V410 PolarHBondContact O-N 3.18Å; V410-V412 VanDerWaalsContact C-N 3.32Å; V410-V412 PolarHBondContact O-N 3.34Å; V410-A413 PolarHBondContact O-N 3.4Å; V410-V414 HydrophobicContact CG1-CG2 3.97Å; V410-V414 WeakPolarHBondContact O-CB 3.37Å; V410-V414 VanDerWaalsContact O-CG2 3.28Å; V410-V414 WeakPolarHBondContact O-CG2 3.21Å; V410-V414 PolarHBondContact O-N 3.25Å
411	L	83.2	Confident	77.2	Confident	86 Å²	86	62.5 Å²	62.5	45%	0.45	32%	0.32	S	S	.	.	H	α-helix	trans	-58.2	-46.4	178.4	-74.1	172	0	0	0	111.1	L407 P408 F415	L407-L411 HydrophobicContact CG-CD1 4.33Å; L407-L411 VanDerWaalsContact O-CG 3.26Å; L407-L411 WeakPolarHBondContact O-CG 3.31Å; L407-L411 PolarHBondContact O-N 3.38Å; P408-L411 PolarHBondContact O-N 2.81Å; L411-F415 HydrophobicContact CD2-CD2 4.07Å; L411-F415 HydrophobicContact CD2-CE2 3.71Å; L411-F415 WeakPolarHBondContact O-CB 3.34Å; L411-F415 VanDerWaalsContact O-CD2 3.25Å; L411-F415 WeakPolarHBondContact O-CD2 3.45Å; L411-F415 PolarHBondContact O-N 3.09Å
412	V	80	Confident	76.6	Confident	36 Å²	36	62.6 Å²	62.6	22%	0.218	32%	0.321	C	S	.	.	H	α-helix	trans	-64.8	-46.2	175.2	177.7	0	0	0	0	110.4	P408 T409 V410 V414 F415 R416 D420 L421 L424	P408-V412 WeakPolarHBondContact O-CG2 3.27Å; P408-V412 PolarHBondContact O-N 3.42Å; T409-V412 PolarHBondContact O-N 3.21Å; V410-V412 VanDerWaalsContact C-N 3.32Å; V410-V412 PolarHBondContact O-N 3.34Å; V412-V414 VanDerWaalsContact C-N 3.27Å; V412-V414 PolarHBondContact O-N 3.39Å; V412-F415 PolarHBondContact O-N 3.1Å; V412-R416 HydrophobicContact CG1-CB 4.12Å; V412-R416 WeakPolarHBondContact O-CA 3.48Å; V412-R416 VanDerWaalsContact O-CB 3.24Å; V412-R416 WeakPolarHBondContact O-CB 3.49Å; V412-R416 PolarHBondContact O-N 3.27Å; V412-D420 HydrophobicContact CG1-CB 4.24Å; V412-L421 HydrophobicContact CB-CD2 4.26Å; V412-L421 HydrophobicContact CG1-CD2 3.86Å; V412-L421 HydrophobicContact CG1-CG 3.96Å; V412-L424 HydrophobicContact CG2-CD2 4.34Å
413	A	78	Confident	75.9	Confident	13 Å²	13	64.1 Å²	64.1	11%	0.107	34%	0.338	C	S	.	.	H	α-helix	trans	-65.3	-24	-178.4	0	0	0	0	0	115	W168 T409 V410 L421	W168-A413 HydrophobicContact CB-CB 4.12Å; T409-A413 VanDerWaalsContact O-CB 3.26Å; T409-A413 WeakPolarHBondContact O-CB 3.45Å; T409-A413 PolarHBondContact O-N 3.41Å; V410-A413 PolarHBondContact O-N 3.4Å; A413-L421 HydrophobicContact CB-CD1 4.16Å; A413-L421 HydrophobicContact CB-CD2 4.38Å
414	V	79.5	Confident	75.4	Confident	82 Å²	82	62.8 Å²	62.8	50%	0.497	33%	0.326	S	S	.	.	H	α-helix	trans	-91.4	-41.5	179	171.7	0	0	0	0	111.8	W168 V410 V412	W168-V414 HydrophobicContact CB-CG2 3.86Å; W168-V414 HydrophobicContact CG-CG2 4.35Å; V410-V414 HydrophobicContact CG1-CG2 3.97Å; V410-V414 WeakPolarHBondContact O-CB 3.37Å; V410-V414 VanDerWaalsContact O-CG2 3.28Å; V410-V414 WeakPolarHBondContact O-CG2 3.21Å; V410-V414 PolarHBondContact O-N 3.25Å; V412-V414 VanDerWaalsContact C-N 3.27Å; V412-V414 PolarHBondContact O-N 3.39Å
415	F	73.9	Confident	75	Confident	159 Å²	159	59.8 Å²	59.8	70%	0.697	31%	0.306	S	S	*	.	H	α-helix	trans	-97.3	-12	-172.2	-67.9	-70.1	0	0	0	114.1	L411 V412	L411-F415 HydrophobicContact CD2-CD2 4.07Å; L411-F415 HydrophobicContact CD2-CE2 3.71Å; L411-F415 WeakPolarHBondContact O-CB 3.34Å; L411-F415 VanDerWaalsContact O-CD2 3.25Å; L411-F415 WeakPolarHBondContact O-CD2 3.45Å; L411-F415 PolarHBondContact O-N 3.09Å; V412-F415 PolarHBondContact O-N 3.1Å
416	R	66.6	Low	74.6	Confident	153 Å²	153	62.8 Å²	62.8	58%	0.577	32%	0.322	S	S	*	.	S	Bend	trans	-132.6	157.3	-174.2	-64.3	-110.3	-177.4	139.7	3.2	111.7	V412 D420	V412-R416 HydrophobicContact CG1-CB 4.12Å; V412-R416 WeakPolarHBondContact O-CA 3.48Å; V412-R416 VanDerWaalsContact O-CB 3.24Å; V412-R416 WeakPolarHBondContact O-CB 3.49Å; V412-R416 PolarHBondContact O-N 3.27Å; R416-D420 HydrophobicContact CB-CB 3.66Å; R416-D420 WeakPolarHBondContact CB-OD2 3.36Å; R416-D420 WeakPolarHBondContact CD-OD2 3.24Å; R416-D420 HydrophobicContact CG-CB 4.31Å; R416-D420 IonicContact NH1-OD1 3.06Å; R416-D420 PolarHBondContact NH1-OD1 2.87Å
417	D	65.1	Low	74.3	Confident	129 Å²	129	66.7 Å²	66.7	69%	0.69	34%	0.342	S	S	*	.			trans	-77.7	166.9	-178	-74.9	-39.1	0	0	0	111.9	R419 D420	D417-R419 PolarHBondContact O-N 3.36Å; D417-D420 WeakPolarHBondContact O-CB 3.36Å; D417-D420 PolarHBondContact O-N 2.9Å
418	L	59.2	Low	74.2	Confident	66 Å²	66	61.3 Å²	61.3	35%	0.346	31%	0.314	S	S	.	.	H	α-helix	trans	-42.5	-39.4	174.5	-87	157.1	0	0	0	114.1	L167 Y343 D420 L421 S422	L167-L418 HydrophobicContact CD1-CD2 3.18Å; L167-L418 HydrophobicContact CD1-CG 3.68Å; L167-L418 HydrophobicContact CD2-CD2 4.21Å; L167-L418 HydrophobicContact CG-CD2 4.1Å; Y343-L418 HydrophobicContact CD1-CD2 4.32Å; Y343-L418 HydrophobicContact CE1-CD1 4.22Å; Y343-L418 HydrophobicContact CE1-CD2 4.5Å; Y343-L418 HydrophobicContact CG-CD2 4.44Å; L418-D420 VanDerWaalsContact C-N 3.27Å; L418-D420 PolarHBondContact O-N 3.01Å; L418-L421 PolarHBondContact O-N 3.48Å; L418-S422 PolarHBondContact O-N 2.92Å; L418-S422 PolarHBondContact O-OG 3.49Å
419	R	61	Low	74.1	Confident	166 Å²	166	59.6 Å²	59.6	63%	0.626	30%	0.303	S	S	*	.	H	α-helix	trans	-65.3	-29.3	-177.7	-65.5	-179.4	-177.9	173.2	2.2	113.3	D417 G423	D417-R419 PolarHBondContact O-N 3.36Å; R419-G423 PolarHBondContact O-N 2.98Å
420	D	65.3	Low	74	Confident	60 Å²	60	62.3 Å²	62.3	32%	0.321	32%	0.319	S	S	.	.	H	α-helix	trans	-77.8	-25.8	178.6	-70.9	-75	0	0	0	112.1	V412 R416 D417 L418 L424	V412-D420 HydrophobicContact CG1-CB 4.24Å; R416-D420 HydrophobicContact CB-CB 3.66Å; R416-D420 WeakPolarHBondContact CB-OD2 3.36Å; R416-D420 WeakPolarHBondContact CD-OD2 3.24Å; R416-D420 HydrophobicContact CG-CB 4.31Å; R416-D420 IonicContact NH1-OD1 3.06Å; R416-D420 PolarHBondContact NH1-OD1 2.87Å; D417-D420 WeakPolarHBondContact O-CB 3.36Å; D417-D420 PolarHBondContact O-N 2.9Å; L418-D420 VanDerWaalsContact C-N 3.27Å; L418-D420 PolarHBondContact O-N 3.01Å; D420-L424 WeakPolarHBondContact O-CB 3.26Å; D420-L424 PolarHBondContact O-N 3.16Å; D420-L424 VanDerWaalsContact O-N 3.13Å
421	L	67.1	Low	74	Confident	10 Å²	10	62.5 Å²	62.5	5%	0.052	32%	0.319	C	S	.	.	H	α-helix	trans	-72.5	-41.1	174.4	-78	160.8	0	0	0	111.8	I151 L167 T409 V412 A413 L418 L424 N425	I151-L421 HydrophobicContact CG1-CD2 4.28Å; L167-L421 HydrophobicContact CB-CD1 4.37Å; L167-L421 HydrophobicContact CD1-CD1 3.39Å; L167-L421 HydrophobicContact CG-CD1 4.43Å; T409-L421 HydrophobicContact CG2-CD2 4.38Å; V412-L421 HydrophobicContact CB-CD2 4.26Å; V412-L421 HydrophobicContact CG1-CD2 3.86Å; V412-L421 HydrophobicContact CG1-CG 3.96Å; A413-L421 HydrophobicContact CB-CD1 4.16Å; A413-L421 HydrophobicContact CB-CD2 4.38Å; L418-L421 PolarHBondContact O-N 3.48Å; L421-L424 WeakPolarHBondContact O-CB 3.34Å; L421-L424 PolarHBondContact O-N 3.32Å; L421-N425 PolarHBondContact O-N 2.89Å
422	S	65	Low	74.2	Confident	12 Å²	12	58.5 Å²	58.5	8%	0.084	30%	0.298	C	S	.	.	H	α-helix	trans	-67.6	-44.6	176.3	-45.8	0	0	0	0	111.2	D341 L418 L424 N425 D426	D341-S422 VanDerWaalsContact CB-CB 3.5Å; D341-S422 WeakPolarHBondContact CB-OG 3.4Å; D341-S422 WeakPolarHBondContact OD2-CB 2.96Å; D341-S422 PolarHBondContact OD2-OG 3.25Å; L418-S422 PolarHBondContact O-N 2.92Å; L418-S422 PolarHBondContact O-OG 3.49Å; S422-L424 PolarHBondContact O-N 3.45Å; S422-N425 WeakPolarHBondContact O-CB 3.42Å; S422-N425 PolarHBondContact O-N 3.07Å; S422-D426 PolarHBondContact O-N 3.09Å
423	G	70.3	Confident	74.4	Confident	38 Å²	38	56.8 Å²	56.8	39%	0.392	29%	0.288	S	S	.	.	H	α-helix	trans	-62.2	-25.9	173.8	0	0	0	0	0	113.7	R419 L427	R419-G423 PolarHBondContact O-N 2.98Å; G423-L427 PolarHBondContact O-N 3.5Å
424	L	75.5	Confident	74.8	Confident	32 Å²	32	58.4 Å²	58.4	17%	0.168	29%	0.294	C	S	.	.	H	α-helix	trans	-68.6	-39.1	170.3	178.8	63.1	0	0	0	111.4	M147 I151 V412 D420 L421 S422 L427 L428	M147-L424 HydrophobicContact CE-CD1 4.16Å; M147-L424 HydrophobicContact CE-CD2 3.76Å; M147-L424 HydrophobicContact CE-CG 4.26Å; I151-L424 HydrophobicContact CD1-CD2 4.03Å; I151-L424 HydrophobicContact CD1-CG 4.33Å; V412-L424 HydrophobicContact CG2-CD2 4.34Å; D420-L424 WeakPolarHBondContact O-CB 3.26Å; D420-L424 PolarHBondContact O-N 3.16Å; D420-L424 VanDerWaalsContact O-N 3.13Å; L421-L424 WeakPolarHBondContact O-CB 3.34Å; L421-L424 PolarHBondContact O-N 3.32Å; S422-L424 PolarHBondContact O-N 3.45Å; L424-L427 PolarHBondContact O-N 2.81Å; L424-L428 HydrophobicContact CD1-CG 4.44Å; L424-L428 HydrophobicContact CG-CD1 4.15Å; L424-L428 HydrophobicContact CG-CG 4.48Å; L424-L428 VanDerWaalsContact O-CG 3.23Å; L424-L428 WeakPolarHBondContact O-CG 3.49Å; L424-L428 PolarHBondContact O-N 2.97Å
425	N	78	Confident	75.3	Confident	0 Å²	0	55 Å²	55	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-65.5	-39.6	178.3	-159.7	31.6	0	0	0	112.5	E76 Q148 L421 S422 L427 L428 N429	E76-N425 VanDerWaalsContact CB-ND2 3.34Å; E76-N425 WeakPolarHBondContact CB-ND2 3.23Å; E76-N425 PolarHBondContact OE2-ND2 2.67Å; Q148-N425 VanDerWaalsContact CB-OD1 3.29Å; Q148-N425 WeakPolarHBondContact CB-OD1 3.47Å; Q148-N425 VanDerWaalsContact CD-OD1 3.29Å; Q148-N425 WeakPolarHBondContact CG-OD1 3.46Å; Q148-N425 PolarHBondContact NE2-OD1 2.98Å; L421-N425 PolarHBondContact O-N 2.89Å; S422-N425 WeakPolarHBondContact O-CB 3.42Å; S422-N425 PolarHBondContact O-N 3.07Å; N425-L427 VanDerWaalsContact C-N 3.31Å; N425-L427 PolarHBondContact O-N 3.12Å; N425-L428 WeakPolarHBondContact O-CB 3.44Å; N425-L428 PolarHBondContact O-N 3.36Å; N425-L428 VanDerWaalsContact O-N 3.14Å; N425-N429 PolarHBondContact O-N 3.19Å
426	D	75.8	Confident	76	Confident	62 Å²	62	47.5 Å²	47.5	33%	0.332	24%	0.24	S	C	.	.	H	α-helix	trans	-57.2	-46	172.8	-67.8	-14.2	0	0	0	111.8	Q80 S422 L428 N429 V430	Q80-D426 PolarHBondContact NE2-OD1 3.23Å; Q80-D426 PolarHBondContact OE1-OD1 2.67Å; S422-D426 PolarHBondContact O-N 3.09Å; D426-L428 VanDerWaalsContact C-N 3.3Å; D426-L428 PolarHBondContact O-N 3.24Å; D426-N429 PolarHBondContact O-N 3.13Å; D426-V430 WeakPolarHBondContact O-CG2 3.43Å; D426-V430 PolarHBondContact O-N 2.64Å
427	L	79.1	Confident	77.2	Confident	98 Å²	98	40.3 Å²	40.3	51%	0.513	21%	0.214	S	C	.	.	H	α-helix	trans	-64.6	-36.4	177.9	-175.7	136.8	0	0	0	111.7	G423 L424 N425 V430 L431	G423-L427 PolarHBondContact O-N 3.5Å; L424-L427 PolarHBondContact O-N 2.81Å; N425-L427 VanDerWaalsContact C-N 3.31Å; N425-L427 PolarHBondContact O-N 3.12Å; L427-V430 PolarHBondContact O-N 2.87Å; L427-L431 WeakPolarHBondContact O-CB 3.44Å; L427-L431 PolarHBondContact O-N 3.13Å
428	L	84.3	Confident	78.5	Confident	6 Å²	6	34.3 Å²	34.3	3%	0.031	18%	0.181	C	C	.	.	H	α-helix	trans	-66.9	-39.7	175.2	-69	170.7	0	0	0	111.7	M147 Q148 I151 L424 N425 D426 V430 L431 Q432	M147-L428 HydrophobicContact CB-CD1 3.66Å; M147-L428 HydrophobicContact CE-CD1 4.31Å; M147-L428 HydrophobicContact CE-CD2 4.5Å; M147-L428 HydrophobicContact SD-CD2 4.29Å; Q148-L428 HydrophobicContact CG-CB 3.77Å; Q148-L428 HydrophobicContact CG-CD1 3.65Å; Q148-L428 HydrophobicContact CG-CG 4.33Å; I151-L428 HydrophobicContact CD1-CD1 4.39Å; L424-L428 HydrophobicContact CD1-CG 4.44Å; L424-L428 HydrophobicContact CG-CD1 4.15Å; L424-L428 HydrophobicContact CG-CG 4.48Å; L424-L428 VanDerWaalsContact O-CG 3.23Å; L424-L428 WeakPolarHBondContact O-CG 3.49Å; L424-L428 PolarHBondContact O-N 2.97Å; N425-L428 WeakPolarHBondContact O-CB 3.44Å; N425-L428 PolarHBondContact O-N 3.36Å; N425-L428 VanDerWaalsContact O-N 3.14Å; D426-L428 VanDerWaalsContact C-N 3.3Å; D426-L428 PolarHBondContact O-N 3.24Å; L428-V430 PolarHBondContact O-N 3.38Å; L428-L431 HydrophobicContact CD2-CD2 4.23Å; L428-L431 WeakPolarHBondContact O-CB 3.47Å; L428-L431 PolarHBondContact O-N 2.9Å; L428-Q432 WeakPolarHBondContact O-CG 3.3Å; L428-Q432 PolarHBondContact O-N 2.65Å
429	N	82.6	Confident	80.1	Confident	8 Å²	8	31.1 Å²	31.1	4%	0.043	17%	0.165	C	C	.	.	H	α-helix	trans	-62.5	-42.3	173.8	-81.1	-24.1	0	0	0	112.1	G73 Q148 N425 D426 L431 Q432 S433	G73-N429 PolarHBondContact O-ND2 2.96Å; Q148-N429 PolarHBondContact NE2-OD1 3.4Å; N425-N429 PolarHBondContact O-N 3.19Å; D426-N429 PolarHBondContact O-N 3.13Å; N429-L431 VanDerWaalsContact C-N 3.33Å; N429-L431 PolarHBondContact O-N 3.1Å; N429-Q432 PolarHBondContact O-N 3.46Å; N429-S433 PolarHBondContact O-N 3.48Å
430	V	79.8	Confident	81.6	Confident	57 Å²	57	23.3 Å²	23.3	35%	0.345	14%	0.135	S	C	.	.	H	α-helix	trans	-63	-41.5	173.5	175.4	0	0	0	0	110.9	D426 L427 L428 Q432 S433 L434 F480	D426-V430 WeakPolarHBondContact O-CG2 3.43Å; D426-V430 PolarHBondContact O-N 2.64Å; L427-V430 PolarHBondContact O-N 2.87Å; L428-V430 PolarHBondContact O-N 3.38Å; V430-Q432 PolarHBondContact O-N 2.96Å; V430-S433 PolarHBondContact O-N 3.43Å; V430-L434 HydrophobicContact CG1-CD1 4.23Å; V430-L434 WeakPolarHBondContact O-CG 3.28Å; V430-L434 PolarHBondContact O-N 3.27Å; V430-F480 HydrophobicContact CG1-CD1 4.39Å; V430-F480 HydrophobicContact CG1-CE1 4.07Å; V430-F480 HydrophobicContact CG1-CZ 4.39Å
431	L	84.8	Confident	82.9	Confident	40 Å²	40	20.4 Å²	20.4	21%	0.209	12%	0.12	C	C	.	.	H	α-helix	trans	-59.3	-44	174.8	179.5	68.3	0	0	0	111.5	L140 L427 L428 N429 S433 L434 L435	L140-L431 HydrophobicContact CD2-CD1 4.19Å; L140-L431 HydrophobicContact CG-CD2 4.31Å; L427-L431 WeakPolarHBondContact O-CB 3.44Å; L427-L431 PolarHBondContact O-N 3.13Å; L428-L431 HydrophobicContact CD2-CD2 4.23Å; L428-L431 WeakPolarHBondContact O-CB 3.47Å; L428-L431 PolarHBondContact O-N 2.9Å; N429-L431 VanDerWaalsContact C-N 3.33Å; N429-L431 PolarHBondContact O-N 3.1Å; L431-S433 VanDerWaalsContact C-N 3.35Å; L431-S433 PolarHBondContact O-N 3.41Å; L431-L434 PolarHBondContact O-N 3.35Å; L431-L435 HydrophobicContact CD1-CD1 3.89Å; L431-L435 HydrophobicContact CD1-CG 4.2Å; L431-L435 HydrophobicContact CD2-CD1 4.47Å; L431-L435 HydrophobicContact CG-CD1 3.79Å; L431-L435 HydrophobicContact CG-CG 4.43Å; L431-L435 VanDerWaalsContact O-CG 3.23Å; L431-L435 WeakPolarHBondContact O-CG 3.24Å; L431-L435 PolarHBondContact O-N 2.94Å
432	Q	86.7	Confident	84.1	Confident	1 Å²	1	20 Å²	20	1%	0.005	12%	0.117	C	C	.	.	H	α-helix	trans	-60.2	-44.3	175.6	-64.4	-54.7	-27.5	0	0	111.7	A141 L428 N429 V430 L434 L435 L436	A141-Q432 PolarHBondContact O-NE2 3.3Å; L428-Q432 WeakPolarHBondContact O-CG 3.3Å; L428-Q432 PolarHBondContact O-N 2.65Å; N429-Q432 PolarHBondContact O-N 3.46Å; V430-Q432 PolarHBondContact O-N 2.96Å; Q432-L434 VanDerWaalsContact C-N 3.29Å; Q432-L434 PolarHBondContact O-N 3.04Å; Q432-L435 PolarHBondContact O-N 2.77Å; Q432-L436 PolarHBondContact O-N 2.93Å; Q432-L436 VanDerWaalsContact O-N 3.09Å
433	S	84.9	Confident	85.4	Confident	1 Å²	1	19.4 Å²	19.4	1%	0.007	11%	0.113	C	C	.	.	H	α-helix	trans	-60.9	-38.8	175.6	-175.2	0	0	0	0	112.2	N429 V430 L431 L436 N477	N429-S433 PolarHBondContact O-N 3.48Å; V430-S433 PolarHBondContact O-N 3.43Å; L431-S433 VanDerWaalsContact C-N 3.35Å; L431-S433 PolarHBondContact O-N 3.41Å; S433-L436 VanDerWaalsContact O-CB 3.25Å; S433-L436 WeakPolarHBondContact O-CB 3.03Å; S433-L436 PolarHBondContact O-N 3.07Å; S433-N477 PolarHBondContact O-ND2 3.22Å; S433-N477 PolarHBondContact O-OD1 3.49Å; S433-N477 VanDerWaalsContact O-OD1 3.07Å
434	L	85.9	Confident	86.4	Confident	47 Å²	47	17.6 Å²	17.6	25%	0.246	10%	0.095	C	C	.	.	H	α-helix	trans	-66.4	-37.2	177.7	-77.8	172.4	0	0	0	112.4	V430 L431 Q432 L436 P437 N477 F480 Y504	V430-L434 HydrophobicContact CG1-CD1 4.23Å; V430-L434 WeakPolarHBondContact O-CG 3.28Å; V430-L434 PolarHBondContact O-N 3.27Å; L431-L434 PolarHBondContact O-N 3.35Å; Q432-L434 VanDerWaalsContact C-N 3.29Å; Q432-L434 PolarHBondContact O-N 3.04Å; L434-L436 VanDerWaalsContact C-N 3.32Å; L434-P437 WeakPolarHBondContact O-CD 3.42Å; L434-N477 WeakPolarHBondContact CA-OD1 3.49Å; L434-N477 PolarHBondContact O-OD1 2.74Å; L434-F480 HydrophobicContact CD2-CB 3.92Å; L434-F480 HydrophobicContact CD2-CG 4.5Å; L434-Y504 WeakPolarHBondContact O-CE2 3.46Å; L434-Y504 PolarHBondContact O-OH 3.41Å
435	L	90.4	Very high	87.1	Confident	9 Å²	9	16 Å²	16	5%	0.047	9%	0.087	C	C	.	.	H	α-helix	trans	-82.8	-10.7	-177.8	-62.4	171.7	0	0	0	113	T137 L140 A141 P251 L431 Q432 F438	T137-L435 HydrophobicContact CG2-CD2 4.32Å; L140-L435 HydrophobicContact CB-CD1 4.37Å; L140-L435 HydrophobicContact CD2-CD1 4.37Å; L140-L435 HydrophobicContact CG-CD1 4.24Å; A141-L435 HydrophobicContact CB-CB 4.35Å; A141-L435 HydrophobicContact CB-CD1 3.69Å; P251-L435 HydrophobicContact CG-CB 4.23Å; L431-L435 HydrophobicContact CD1-CD1 3.89Å; L431-L435 HydrophobicContact CD1-CG 4.2Å; L431-L435 HydrophobicContact CD2-CD1 4.47Å; L431-L435 HydrophobicContact CG-CD1 3.79Å; L431-L435 HydrophobicContact CG-CG 4.43Å; L431-L435 VanDerWaalsContact O-CG 3.23Å; L431-L435 WeakPolarHBondContact O-CG 3.24Å; L431-L435 PolarHBondContact O-N 2.94Å; Q432-L435 PolarHBondContact O-N 2.77Å; L435-F438 HydrophobicContact CB-CD2 4.45Å; L435-F438 HydrophobicContact CD2-CD2 3.98Å; L435-F438 HydrophobicContact CD2-CE2 4.09Å; L435-F438 WeakPolarHBondContact O-CB 3.41Å; L435-F438 PolarHBondContact O-N 3.34Å; L435-F438 VanDerWaalsContact O-N 3.11Å
436	L	88.9	Confident	87.7	Confident	3 Å²	3	16 Å²	16	2%	0.016	9%	0.087	C	C	.	.	H	α-helix	trans	-49.4	-46.2	179.9	-173.3	57.7	0	0	0	116	I249 Q432 S433 L434 F438 A439 V440 V473	I249-L436 HydrophobicContact CB-CD1 3.94Å; I249-L436 HydrophobicContact CB-CD2 4.38Å; I249-L436 HydrophobicContact CG2-CD1 3.61Å; I249-L436 WeakPolarHBondContact O-CD1 3.32Å; Q432-L436 PolarHBondContact O-N 2.93Å; Q432-L436 VanDerWaalsContact O-N 3.09Å; S433-L436 VanDerWaalsContact O-CB 3.25Å; S433-L436 WeakPolarHBondContact O-CB 3.03Å; S433-L436 PolarHBondContact O-N 3.07Å; L434-L436 VanDerWaalsContact C-N 3.32Å; L436-F438 PolarHBondContact O-N 2.91Å; L436-F438 VanDerWaalsContact O-N 3.13Å; L436-A439 PolarHBondContact O-N 3.06Å; L436-A439 VanDerWaalsContact O-N 3.14Å; L436-V440 HydrophobicContact CD1-CG2 3.55Å; L436-V440 HydrophobicContact CG-CG2 3.93Å; L436-V440 PolarHBondContact O-N 3.33Å; L436-V473 HydrophobicContact CD2-CG1 4.4Å; L436-V473 HydrophobicContact CD2-CG2 4.05Å; L436-V473 HydrophobicContact CG-CG1 4.24Å; L436-V473 HydrophobicContact CG-CG2 4.45Å
437	P	91.4	Very high	88.5	Confident	2 Å²	2	13.1 Å²	13.1	1%	0.013	7%	0.071	C	C	.	.	H	α-helix	trans	-59.1	-30.1	-178.4	-19.9	31.3	0	0	0	112.7	L434 A439 V440 L441 V473 N477	L434-P437 WeakPolarHBondContact O-CD 3.42Å; P437-A439 VanDerWaalsContact C-N 3.29Å; P437-A439 PolarHBondContact O-N 2.84Å; P437-V440 PolarHBondContact O-N 3.39Å; P437-L441 HydrophobicContact CB-CD1 3.87Å; P437-L441 HydrophobicContact CB-CG 4.25Å; P437-L441 WeakPolarHBondContact O-CB 3.43Å; P437-L441 WeakPolarHBondContact O-CG 3.28Å; P437-L441 PolarHBondContact O-N 3.35Å; P437-V473 HydrophobicContact CB-CG1 3.97Å; P437-V473 HydrophobicContact CG-CG1 3.67Å; P437-N477 HydrophobicContact CG-CB 4.22Å; P437-N477 VanDerWaalsContact CG-ND2 3.32Å; P437-N477 WeakPolarHBondContact CG-ND2 3.42Å
438	F	92.6	Very high	88.9	Confident	2 Å²	2	8.4 Å²	8.4	1%	0.009	5%	0.047	C	C	.	.	H	α-helix	trans	-71.5	-22.4	-177	-59.4	-48	0	0	0	113.1	L134 T137 I138 Y255 L435 L436 P442 Y504 L507 L511	L134-F438 HydrophobicContact CD1-CB 3.56Å; L134-F438 HydrophobicContact CD1-CD1 4.46Å; L134-F438 HydrophobicContact CD1-CG 4.33Å; L134-F438 WeakPolarHBondContact CD1-O 3.49Å; T137-F438 HydrophobicContact CG2-CD2 3.85Å; T137-F438 HydrophobicContact CG2-CE2 3.83Å; T137-F438 HydrophobicContact CG2-CG 4.42Å; T137-F438 HydrophobicContact CG2-CZ 4.43Å; I138-F438 HydrophobicContact CD1-CB 4.19Å; Y255-F438 PolarHBondContact OH-O 3.03Å; Y255-F438 VanDerWaalsContact OH-O 3.12Å; L435-F438 HydrophobicContact CB-CD2 4.45Å; L435-F438 HydrophobicContact CD2-CD2 3.98Å; L435-F438 HydrophobicContact CD2-CE2 4.09Å; L435-F438 WeakPolarHBondContact O-CB 3.41Å; L435-F438 PolarHBondContact O-N 3.34Å; L435-F438 VanDerWaalsContact O-N 3.11Å; L436-F438 PolarHBondContact O-N 2.91Å; L436-F438 VanDerWaalsContact O-N 3.13Å; F438-P442 VanDerWaalsContact O-CD 3.24Å; F438-P442 WeakPolarHBondContact O-CD 3.44Å; F438-P442 VanDerWaalsContact O-CG 3.22Å; F438-P442 WeakPolarHBondContact O-CG 3.2Å; F438-Y504 HydrophobicContact CD2-CE2 4.46Å; F438-Y504 AromaticContact CE2-CD2 3.55Å; F438-Y504 HydrophobicContact CE2-CD2 3.55Å; F438-Y504 AromaticContact CE2-CE2 3.32Å; F438-Y504 HydrophobicContact CE2-CE2 3.32Å; F438-Y504 AromaticContact CZ-CD2 3.37Å; F438-Y504 HydrophobicContact CZ-CD2 3.37Å; F438-Y504 AromaticContact CZ-CE2 3.38Å; F438-Y504 HydrophobicContact CZ-CE2 3.38Å; F438-Y504 HydrophobicContact CZ-CG 4.22Å; F438-L507 HydrophobicContact CD1-CD2 3.89Å; F438-L507 HydrophobicContact CD1-CG 4.17Å; F438-L507 HydrophobicContact CE1-CB 4.06Å; F438-L507 HydrophobicContact CE1-CD2 3.52Å; F438-L507 HydrophobicContact CE1-CG 3.68Å; F438-L507 HydrophobicContact CZ-CD2 4.08Å; F438-L511 HydrophobicContact CD1-CD1 3.67Å; F438-L511 HydrophobicContact CE1-CD1 4.33Å
439	A	92	Very high	88.9	Confident	0 Å²	0	8.2 Å²	8.2	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-94.3	-41.6	169.9	0	0	0	0	0	112.3	I138 P251 I254 Y255 L436 P437 I443	I138-A439 HydrophobicContact CD1-CB 4.3Å; P251-A439 VanDerWaalsContact CA-CB 3.49Å; P251-A439 HydrophobicContact CB-CB 3.59Å; P251-A439 VanDerWaalsContact O-CB 3.27Å; P251-A439 WeakPolarHBondContact O-CB 3.5Å; I254-A439 HydrophobicContact CB-CB 4.38Å; I254-A439 HydrophobicContact CD1-CB 3.98Å; Y255-A439 HydrophobicContact CD2-CB 4.21Å; Y255-A439 HydrophobicContact CE2-CB 3.63Å; L436-A439 PolarHBondContact O-N 3.06Å; L436-A439 VanDerWaalsContact O-N 3.14Å; P437-A439 VanDerWaalsContact C-N 3.29Å; P437-A439 PolarHBondContact O-N 2.84Å; A439-I443 WeakPolarHBondContact O-CG2 3.39Å; A439-I443 PolarHBondContact O-N 3.38Å
440	V	92.6	Very high	88.9	Confident	1 Å²	1	11.8 Å²	11.8	1%	0.006	7%	0.069	C	C	.	.	H	α-helix	trans	-71.8	-44.6	-173.7	175.3	0	0	0	0	111.7	I249 I254 L436 P437 I443 L444 I469 V473	I249-V440 HydrophobicContact CG2-CG2 4.38Å; I254-V440 HydrophobicContact CD1-CG2 3.74Å; L436-V440 HydrophobicContact CD1-CG2 3.55Å; L436-V440 HydrophobicContact CG-CG2 3.93Å; L436-V440 PolarHBondContact O-N 3.33Å; P437-V440 PolarHBondContact O-N 3.39Å; V440-I443 WeakPolarHBondContact O-CG2 3.23Å; V440-I443 PolarHBondContact O-N 3.48Å; V440-L444 HydrophobicContact CG1-CD1 3.57Å; V440-L444 HydrophobicContact CG1-CG 3.98Å; V440-L444 WeakPolarHBondContact O-CG 3.5Å; V440-L444 PolarHBondContact O-N 3.02Å; V440-I469 HydrophobicContact CG1-CG2 3.89Å; V440-V473 HydrophobicContact CG1-CG2 4.4Å
441	L	92.6	Very high	89.1	Confident	0 Å²	0	11.2 Å²	11.2	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-64	-44.3	-176.8	-61.8	172.9	0	0	0	113	P437 I443 L444 T445 M470 L511 V512	P437-L441 HydrophobicContact CB-CD1 3.87Å; P437-L441 HydrophobicContact CB-CG 4.25Å; P437-L441 WeakPolarHBondContact O-CB 3.43Å; P437-L441 WeakPolarHBondContact O-CG 3.28Å; P437-L441 PolarHBondContact O-N 3.35Å; L441-I443 PolarHBondContact O-N 2.83Å; L441-L444 PolarHBondContact O-N 3.26Å; L441-T445 WeakPolarHBondContact O-CB 3.23Å; L441-T445 PolarHBondContact O-N 3.47Å; L441-T445 PolarHBondContact O-OG1 3.37Å; L441-M470 HydrophobicContact CD2-CB 4.34Å; L441-M470 HydrophobicContact CD2-CG 3.62Å; L441-M470 HydrophobicContact CD2-SD 4.36Å; L441-L511 HydrophobicContact CB-CB 3.92Å; L441-L511 HydrophobicContact CD1-CB 3.63Å; L441-L511 HydrophobicContact CD1-CD1 4.42Å; L441-L511 HydrophobicContact CG-CB 4.44Å; L441-V512 HydrophobicContact CD1-CG2 3.79Å; L441-V512 HydrophobicContact CD2-CG2 4.17Å
442	P	92.9	Very high	89.1	Confident	0 Å²	0	10.7 Å²	10.7	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-59	-44.4	174.1	-28.6	38.3	0	0	0	113.2	L118 Y126 L134 F438 L444 T445 F446 L511	L118-P442 HydrophobicContact CD1-CB 4.2Å; Y126-P442 HydrophobicContact CE2-CB 4.3Å; Y126-P442 HydrophobicContact CE2-CG 4.33Å; L134-P442 HydrophobicContact CD2-CG 4.01Å; F438-P442 VanDerWaalsContact O-CD 3.24Å; F438-P442 WeakPolarHBondContact O-CD 3.44Å; F438-P442 VanDerWaalsContact O-CG 3.22Å; F438-P442 WeakPolarHBondContact O-CG 3.2Å; P442-L444 PolarHBondContact O-N 3.24Å; P442-T445 WeakPolarHBondContact O-CB 3.38Å; P442-T445 PolarHBondContact O-N 3.48Å; P442-F446 HydrophobicContact CB-CD2 4.24Å; P442-F446 HydrophobicContact CB-CE2 4.05Å; P442-F446 WeakPolarHBondContact O-CD2 3.47Å; P442-F446 PolarHBondContact O-N 2.86Å; P442-L511 HydrophobicContact CG-CD2 4.39Å
443	I	92.9	Very high	89.1	Confident	0 Å²	0	10.6 Å²	10.6	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-66.4	-39.3	-178.9	-169.6	60.1	0	0	0	111.8	L106 A107 L110 L118 I254 A439 V440 L441 T445 T447	L106-I443 HydrophobicContact CB-CG1 3.9Å; A107-I443 HydrophobicContact CB-CD1 4.49Å; L110-I443 HydrophobicContact CB-CD1 3.82Å; L110-I443 HydrophobicContact CD2-CD1 3.63Å; L110-I443 HydrophobicContact CG-CD1 4.3Å; L118-I443 HydrophobicContact CD1-CB 4.4Å; L118-I443 HydrophobicContact CD1-CD1 4.18Å; L118-I443 HydrophobicContact CD2-CB 4.13Å; I254-I443 HydrophobicContact CG2-CB 4.1Å; I254-I443 HydrophobicContact CG2-CG1 4.28Å; I254-I443 HydrophobicContact CG2-CG2 4.03Å; A439-I443 WeakPolarHBondContact O-CG2 3.39Å; A439-I443 PolarHBondContact O-N 3.38Å; V440-I443 WeakPolarHBondContact O-CG2 3.23Å; V440-I443 PolarHBondContact O-N 3.48Å; L441-I443 PolarHBondContact O-N 2.83Å; I443-T445 VanDerWaalsContact C-N 3.33Å; I443-T445 PolarHBondContact O-N 2.83Å; I443-T447 HydrophobicContact CD1-CG2 3.64Å; I443-T447 HydrophobicContact CG1-CG2 4.05Å; I443-T447 VanDerWaalsContact O-CB 3.28Å; I443-T447 WeakPolarHBondContact O-CB 3.2Å; I443-T447 WeakPolarHBondContact O-CG2 3.38Å; I443-T447 PolarHBondContact O-N 3.32Å; I443-T447 VanDerWaalsContact O-N 3.08Å; I443-T447 PolarHBondContact O-OG1 2.86Å
444	L	91.7	Very high	89.1	Confident	0 Å²	0	17 Å²	17	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-65.2	-38.1	175.3	-61.3	175	0	0	0	111.8	L106 V440 L441 P442 T447 S448 T466 I469 M470	L106-L444 HydrophobicContact CD1-CD2 3.72Å; V440-L444 HydrophobicContact CG1-CD1 3.57Å; V440-L444 HydrophobicContact CG1-CG 3.98Å; V440-L444 WeakPolarHBondContact O-CG 3.5Å; V440-L444 PolarHBondContact O-N 3.02Å; L441-L444 PolarHBondContact O-N 3.26Å; P442-L444 PolarHBondContact O-N 3.24Å; L444-T447 PolarHBondContact O-OG1 3.41Å; L444-S448 WeakPolarHBondContact O-CB 3.37Å; L444-S448 PolarHBondContact O-N 3.08Å; L444-S448 PolarHBondContact O-OG 3.41Å; L444-T466 HydrophobicContact CD2-CG2 3.44Å; L444-T466 VanDerWaalsContact CD2-CG2 3.44Å; L444-I469 HydrophobicContact CD1-CB 4.41Å; L444-I469 HydrophobicContact CD1-CG2 4.24Å; L444-M470 HydrophobicContact CD1-CB 4.02Å
445	T	90.1	Very high	89	Confident	0 Å²	0	21.1 Å²	21.1	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-63.7	-60.1	177.3	-56.8	0	0	0	0	110.6	L441 P442 I443 T447 S448 M449 C515 A518 F532	L441-T445 WeakPolarHBondContact O-CB 3.23Å; L441-T445 PolarHBondContact O-N 3.47Å; L441-T445 PolarHBondContact O-OG1 3.37Å; P442-T445 WeakPolarHBondContact O-CB 3.38Å; P442-T445 PolarHBondContact O-N 3.48Å; I443-T445 VanDerWaalsContact C-N 3.33Å; I443-T445 PolarHBondContact O-N 2.83Å; T445-T447 VanDerWaalsContact C-N 3.34Å; T445-T447 PolarHBondContact O-N 2.94Å; T445-S448 PolarHBondContact O-N 3.44Å; T445-S448 VanDerWaalsContact O-N 3.09Å; T445-M449 HydrophobicContact CG2-SD 4.22Å; T445-M449 WeakPolarHBondContact O-CG 3.01Å; T445-M449 PolarHBondContact O-N 3.06Å; T445-C515 VanDerWaalsContact OG1-CA 3.23Å; T445-C515 WeakPolarHBondContact OG1-CA 3.24Å; T445-C515 VanDerWaalsContact OG1-CB 3.27Å; T445-C515 WeakPolarHBondContact OG1-CB 3.4Å; T445-C515 PolarHBondContact OG1-N 3.37Å; T445-A518 HydrophobicContact CG2-CB 3.73Å; T445-A518 WeakPolarHBondContact O-CB 3.25Å; T445-F532 HydrophobicContact CG2-CE1 4.38Å
446	F	90.9	Very high	88.8	Confident	0 Å²	0	21.9 Å²	21.9	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-67.3	-33.1	-173	-68.4	-51.2	0	0	0	113.2	L110 L118 V121 Y125 Y126 P442 S448 M449 L452 F532	L110-F446 HydrophobicContact CD1-CB 4.01Å; L118-F446 HydrophobicContact CD1-CD2 3.85Å; L118-F446 HydrophobicContact CD1-CE2 4.43Å; V121-F446 HydrophobicContact CG1-CB 4.27Å; V121-F446 HydrophobicContact CG1-CD1 3.62Å; V121-F446 HydrophobicContact CG1-CD2 3.7Å; V121-F446 HydrophobicContact CG1-CE1 3.84Å; V121-F446 HydrophobicContact CG1-CE2 3.9Å; V121-F446 HydrophobicContact CG1-CG 3.58Å; V121-F446 HydrophobicContact CG1-CZ 3.97Å; Y125-F446 HydrophobicContact CD1-CE1 4.35Å; Y125-F446 HydrophobicContact CD2-CD1 4.44Å; Y125-F446 AromaticContact CD2-CE1 3.86Å; Y125-F446 HydrophobicContact CD2-CE1 3.86Å; Y125-F446 AromaticContact CG-CE1 3.67Å; Y125-F446 HydrophobicContact CG-CE1 3.67Å; Y125-F446 HydrophobicContact CG-CZ 4.36Å; Y126-F446 HydrophobicContact CD2-CZ 4.2Å; Y126-F446 AromaticContact CE2-CE2 3.81Å; Y126-F446 HydrophobicContact CE2-CE2 3.81Å; Y126-F446 AromaticContact CE2-CZ 3.71Å; Y126-F446 HydrophobicContact CE2-CZ 3.71Å; P442-F446 HydrophobicContact CB-CD2 4.24Å; P442-F446 HydrophobicContact CB-CE2 4.05Å; P442-F446 WeakPolarHBondContact O-CD2 3.47Å; P442-F446 PolarHBondContact O-N 2.86Å; F446-S448 PolarHBondContact O-N 2.83Å; F446-M449 HydrophobicContact CD1-SD 3.61Å; F446-M449 HydrophobicContact CE1-SD 4.1Å; F446-M449 PolarHBondContact O-N 3.43Å; F446-L452 HydrophobicContact CB-CD2 3.72Å; F446-L452 HydrophobicContact CD1-CD2 4Å; F446-L452 HydrophobicContact CG-CD2 4.15Å; F446-F532 AromaticContact CE1-CE1 3.86Å; F446-F532 HydrophobicContact CE1-CE1 3.86Å; F446-F532 HydrophobicContact CZ-CE1 4.38Å
447	T	90.5	Very high	88.6	Confident	0 Å²	0	23.1 Å²	23.1	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-73	-17.9	176.6	61	0	0	0	0	113.5	L106 L110 I443 L444 T445 M453 N458	L106-T447 HydrophobicContact CB-CG2 3.99Å; L106-T447 HydrophobicContact CD2-CG2 4.29Å; L110-T447 HydrophobicContact CB-CG2 4.29Å; I443-T447 HydrophobicContact CD1-CG2 3.64Å; I443-T447 HydrophobicContact CG1-CG2 4.05Å; I443-T447 VanDerWaalsContact O-CB 3.28Å; I443-T447 WeakPolarHBondContact O-CB 3.2Å; I443-T447 WeakPolarHBondContact O-CG2 3.38Å; I443-T447 PolarHBondContact O-N 3.32Å; I443-T447 VanDerWaalsContact O-N 3.08Å; I443-T447 PolarHBondContact O-OG1 2.86Å; L444-T447 PolarHBondContact O-OG1 3.41Å; T445-T447 VanDerWaalsContact C-N 3.34Å; T445-T447 PolarHBondContact O-N 2.94Å; T447-M453 HydrophobicContact CG2-CE 3.33Å; T447-N458 VanDerWaalsContact O-CG 3.32Å; T447-N458 PolarHBondContact O-N 3.16Å; T447-N458 PolarHBondContact O-ND2 3.12Å; T447-N458 PolarHBondContact OG1-ND2 3.4Å; T447-N458 VanDerWaalsContact OG1-ND2 3.1Å
448	S	87.8	Confident	88.3	Confident	0 Å²	0	23.4 Å²	23.4	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-94.1	-10.6	177.6	-59.9	0	0	0	0	113.5	L444 T445 F446 P450 N458 H519	L444-S448 WeakPolarHBondContact O-CB 3.37Å; L444-S448 PolarHBondContact O-N 3.08Å; L444-S448 PolarHBondContact O-OG 3.41Å; T445-S448 PolarHBondContact O-N 3.44Å; T445-S448 VanDerWaalsContact O-N 3.09Å; F446-S448 PolarHBondContact O-N 2.83Å; S448-P450 VanDerWaalsContact O-CD 3.31Å; S448-P450 WeakPolarHBondContact O-CD 3.46Å; S448-N458 PolarHBondContact OG-ND2 3.19Å; S448-H519 PolarHBondContact OG-CD2 2.68Å; S448-H519 PolarHBondContact OG-NE2 3.3Å
449	M	85.6	Confident	88	Confident	1 Å²	1	25 Å²	25	1%	0.005	15%	0.147	C	C	.	.			trans	-79.1	116.2	180	-73.8	170.9	64.5	0	0	112.1	Y125 T445 F446 A451 L452 M453 A518 F532	Y125-M449 HydrophobicContact CD1-CE 3.9Å; Y125-M449 HydrophobicContact CE1-CE 3.5Å; T445-M449 HydrophobicContact CG2-SD 4.22Å; T445-M449 WeakPolarHBondContact O-CG 3.01Å; T445-M449 PolarHBondContact O-N 3.06Å; F446-M449 HydrophobicContact CD1-SD 3.61Å; F446-M449 HydrophobicContact CE1-SD 4.1Å; F446-M449 PolarHBondContact O-N 3.43Å; M449-A451 VanDerWaalsContact C-N 3.28Å; M449-A451 PolarHBondContact O-N 3.27Å; M449-L452 HydrophobicContact CB-CB 4.22Å; M449-L452 PolarHBondContact O-N 2.93Å; M449-M453 PolarHBondContact O-N 3.44Å; M449-A518 HydrophobicContact CG-CB 3.68Å; M449-F532 HydrophobicContact CE-CB 4.33Å; M449-F532 HydrophobicContact CE-CD1 3.77Å; M449-F532 HydrophobicContact CE-CG 4.43Å; M449-F532 WeakPolarHBondContact CE-O 3.33Å; M449-F532 HydrophobicContact SD-CD1 3.65Å; M449-F532 HydrophobicContact SD-CE1 4.24Å
450	P	82.9	Confident	87.7	Confident	83 Å²	83	30.4 Å²	30.4	54%	0.539	18%	0.182	S	C	.	.	H	α-helix	trans	-64.8	-31.5	176.7	-20.9	34.1	0	0	0	113.2	S448 L452 Q454	S448-P450 VanDerWaalsContact O-CD 3.31Å; S448-P450 WeakPolarHBondContact O-CD 3.46Å; P450-L452 PolarHBondContact O-N 3.14Å; P450-Q454 VanDerWaalsContact O-CA 3.23Å; P450-Q454 WeakPolarHBondContact O-CA 3.25Å; P450-Q454 PolarHBondContact O-N 2.94Å
451	A	82.7	Confident	87.5	Confident	45 Å²	45	36.8 Å²	36.8	37%	0.372	22%	0.215	S	C	.	.	H	α-helix	trans	-62	-31.3	178	0	0	0	0	0	112.8	M449	M449-A451 VanDerWaalsContact C-N 3.28Å; M449-A451 PolarHBondContact O-N 3.27Å
452	L	85.9	Confident	87.1	Confident	29 Å²	29	38.1 Å²	38.1	15%	0.152	23%	0.225	C	C	.	.	H	α-helix	trans	-95.3	-45.9	-178.8	-174.5	67	0	0	0	112.3	L110 T114 V121 Y125 F446 M449 P450	L110-L452 HydrophobicContact CD1-CD2 3.76Å; T114-L452 HydrophobicContact CG2-CD1 3.68Å; T114-L452 HydrophobicContact CG2-CD2 4.14Å; T114-L452 HydrophobicContact CG2-CG 3.65Å; V121-L452 HydrophobicContact CG1-CD2 3.72Å; Y125-L452 HydrophobicContact CE2-CD1 4.07Å; F446-L452 HydrophobicContact CB-CD2 3.72Å; F446-L452 HydrophobicContact CD1-CD2 4Å; F446-L452 HydrophobicContact CG-CD2 4.15Å; M449-L452 HydrophobicContact CB-CB 4.22Å; M449-L452 PolarHBondContact O-N 2.93Å; P450-L452 PolarHBondContact O-N 3.14Å
453	M	85.8	Confident	86.7	Confident	0 Å²	0	41.4 Å²	41.4	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-89.2	-8.9	-174.8	-73.6	-68.5	-152.5	0	0	114.2	R109 L110 V113 T447 M449 E455 F456 A457	R109-M453 HydrophobicContact CB-CE 4.41Å; L110-M453 HydrophobicContact CB-CE 3.93Å; L110-M453 HydrophobicContact CD1-CE 3.78Å; L110-M453 HydrophobicContact CD1-SD 4.43Å; L110-M453 HydrophobicContact CG-CE 4.49Å; V113-M453 HydrophobicContact CB-SD 3.92Å; V113-M453 HydrophobicContact CG1-SD 3.95Å; V113-M453 HydrophobicContact CG2-SD 4.18Å; T447-M453 HydrophobicContact CG2-CE 3.33Å; M449-M453 PolarHBondContact O-N 3.44Å; M453-E455 PolarHBondContact O-N 3.28Å; M453-F456 CarbonylContact O-C 3.48Å; M453-F456 WeakPolarHBondContact O-CA 3.4Å; M453-F456 WeakPolarHBondContact O-CB 3.41Å; M453-F456 PolarHBondContact O-N 2.91Å; M453-A457 HydrophobicContact CB-CB 4.09Å
454	Q	84.9	Confident	86.5	Confident	134 Å²	134	45.8 Å²	45.8	63%	0.626	27%	0.266	S	S	*	.	G	3₁₀ helix	trans	51	-131	-176.8	-56.7	-174.9	-13.3	0	0	111.6	P450 F456 A457	P450-Q454 VanDerWaalsContact O-CA 3.23Å; P450-Q454 WeakPolarHBondContact O-CA 3.25Å; P450-Q454 PolarHBondContact O-N 2.94Å; Q454-F456 PolarHBondContact O-N 2.92Å; Q454-A457 WeakPolarHBondContact O-CB 3.31Å; Q454-A457 PolarHBondContact O-N 3.41Å
455	E	84.4	Confident	86.4	Confident	134 Å²	134	48.3 Å²	48.3	63%	0.626	28%	0.281	S	S	*	.	G	3₁₀ helix	trans	-66.8	-12.2	177.6	-64.7	178.5	178.6	0	0	113.6	R271 M453 A457	R271-E455 IonicContact CZ-OE1 3.85Å; R271-E455 IonicContact CZ-OE2 2.61Å; R271-E455 IonicContact NE-OE2 3.86Å; R271-E455 IonicContact NH1-OE1 2.83Å; R271-E455 PolarHBondContact NH1-OE1 3.28Å; R271-E455 IonicContact NH1-OE2 2.73Å; R271-E455 PolarHBondContact NH1-OE2 3.2Å; R271-E455 IonicContact NH2-OE1 2.79Å; M453-E455 PolarHBondContact O-N 3.28Å; E455-A457 VanDerWaalsContact C-N 3.34Å
456	F	85.9	Confident	86.2	Confident	26 Å²	26	48.4 Å²	48.4	11%	0.114	28%	0.282	C	S	.	.	G	3₁₀ helix	trans	-94.4	15.1	176.7	-59	-81	0	0	0	112.6	R109 V113 I274 R275 M453 Q454	R109-F456 PolarHBondContact NH2-O 2.91Å; V113-F456 HydrophobicContact CG1-CD2 4.34Å; V113-F456 HydrophobicContact CG2-CB 3.92Å; V113-F456 HydrophobicContact CG2-CD2 4.19Å; V113-F456 HydrophobicContact CG2-CG 4.09Å; I274-F456 HydrophobicContact CB-CE2 4.11Å; I274-F456 HydrophobicContact CB-CZ 3.86Å; I274-F456 HydrophobicContact CD1-CE2 4.18Å; I274-F456 HydrophobicContact CG2-CD1 4.35Å; I274-F456 HydrophobicContact CG2-CD2 4.05Å; I274-F456 HydrophobicContact CG2-CE1 3.92Å; I274-F456 HydrophobicContact CG2-CE2 3.59Å; I274-F456 HydrophobicContact CG2-CG 4.4Å; I274-F456 HydrophobicContact CG2-CZ 3.52Å; R275-F456 HydrophobicContact CB-CE1 4.24Å; M453-F456 CarbonylContact O-C 3.48Å; M453-F456 WeakPolarHBondContact O-CA 3.4Å; M453-F456 WeakPolarHBondContact O-CB 3.41Å; M453-F456 PolarHBondContact O-N 2.91Å; Q454-F456 PolarHBondContact O-N 2.92Å
457	A	85.2	Confident	86.1	Confident	28 Å²	28	50.5 Å²	50.5	23%	0.231	30%	0.297	C	S	.	.	S	Bend	trans	-61.5	156.5	172.8	0	0	0	0	0	112.2	M453 Q454 E455 G459	M453-A457 HydrophobicContact CB-CB 4.09Å; Q454-A457 WeakPolarHBondContact O-CB 3.31Å; Q454-A457 PolarHBondContact O-N 3.41Å; E455-A457 VanDerWaalsContact C-N 3.34Å; A457-G459 PolarHBondContact O-N 3.21Å
458	N	85.4	Confident	86.1	Confident	8 Å²	8	53.9 Å²	53.9	4%	0.043	32%	0.32	C	S	.	.	P	Polyproline II helix	trans	-62.7	125.2	179	-72.6	-18.6	0	0	0	112	R109 T447 S448 K463	R109-N458 PolarHBondContact NH1-OD1 3.34Å; T447-N458 VanDerWaalsContact O-CG 3.32Å; T447-N458 PolarHBondContact O-N 3.16Å; T447-N458 PolarHBondContact O-ND2 3.12Å; T447-N458 PolarHBondContact OG1-ND2 3.4Å; T447-N458 VanDerWaalsContact OG1-ND2 3.1Å; S448-N458 PolarHBondContact OG-ND2 3.19Å; N458-K463 HydrophobicContact CB-CG 4.25Å; N458-K463 WeakPolarHBondContact O-CE 3.46Å
459	G	85.3	Confident	86.2	Confident	37 Å²	37	54.3 Å²	54.3	38%	0.381	32%	0.322	S	S	.	.	P	Polyproline II helix	trans	-68.7	172.8	172.3	0	0	0	0	0	112.9	A457 L461 S462 K463	A457-G459 PolarHBondContact O-N 3.21Å; G459-L461 PolarHBondContact O-N 3.24Å; G459-S462 WeakPolarHBondContact O-CB 3.29Å; G459-S462 PolarHBondContact O-N 3.42Å; G459-K463 PolarHBondContact O-N 2.93Å
460	P	85.1	Confident	86.3	Confident	112 Å²	112	55 Å²	55	73%	0.727	33%	0.326	S	S	*	.	H	α-helix	trans	-60.5	-42	-172.2	23.5	-33.6	0	0	0	113.1	S462 K463 V464	P460-S462 PolarHBondContact O-N 3.07Å; P460-K463 WeakPolarHBondContact O-CB 3.48Å; P460-K463 PolarHBondContact O-N 3.39Å; P460-V464 WeakPolarHBondContact O-CG2 3.31Å; P460-V464 PolarHBondContact O-N 3.07Å
461	L	88.3	Confident	86.7	Confident	135 Å²	135	55.4 Å²	55.4	71%	0.707	33%	0.326	S	S	*	.	H	α-helix	trans	-62.1	-44.2	175	-180	64.5	0	0	0	111.6	G459 K463 V464 V465	G459-L461 PolarHBondContact O-N 3.24Å; L461-K463 VanDerWaalsContact C-N 3.27Å; L461-K463 PolarHBondContact O-N 3.42Å; L461-V464 PolarHBondContact O-N 3.38Å; L461-V465 WeakPolarHBondContact O-CG2 3.28Å; L461-V465 PolarHBondContact O-N 2.92Å
462	S	85.5	Confident	87	Confident	29 Å²	29	57.1 Å²	57.1	20%	0.203	33%	0.329	C	S	.	.	H	α-helix	trans	-63.2	-36.1	177.4	-169	0	0	0	0	111.2	G459 P460 V465 T466	G459-S462 WeakPolarHBondContact O-CB 3.29Å; G459-S462 PolarHBondContact O-N 3.42Å; P460-S462 PolarHBondContact O-N 3.07Å; S462-V465 PolarHBondContact O-N 3.21Å; S462-T466 VanDerWaalsContact O-CG2 3.31Å; S462-T466 WeakPolarHBondContact O-CG2 3.17Å; S462-T466 PolarHBondContact O-N 3.23Å; S462-T466 PolarHBondContact O-OG1 3.15Å; S462-T466 VanDerWaalsContact O-OG1 3.08Å
463	K	85	Confident	87	Confident	68 Å²	68	55.9 Å²	55.9	30%	0.296	32%	0.323	S	S	.	.	H	α-helix	trans	-65.3	-40	175.2	-72.5	-175.7	176.6	-168.6	0	112.9	N458 G459 P460 L461 T466 S467	N458-K463 HydrophobicContact CB-CG 4.25Å; N458-K463 WeakPolarHBondContact O-CE 3.46Å; G459-K463 PolarHBondContact O-N 2.93Å; P460-K463 WeakPolarHBondContact O-CB 3.48Å; P460-K463 PolarHBondContact O-N 3.39Å; L461-K463 VanDerWaalsContact C-N 3.27Å; L461-K463 PolarHBondContact O-N 3.42Å; K463-T466 VanDerWaalsContact CA-OG1 3.31Å; K463-T466 WeakPolarHBondContact CA-OG1 3.23Å; K463-T466 PolarHBondContact O-OG1 2.72Å; K463-T466 VanDerWaalsContact O-OG1 3.05Å; K463-S467 WeakPolarHBondContact O-CB 3.45Å; K463-S467 PolarHBondContact O-N 3.29Å
464	V	88.6	Confident	87.1	Confident	93 Å²	93	57.8 Å²	57.8	56%	0.564	34%	0.335	S	S	*	.	H	α-helix	trans	-61.9	-47.8	174.4	174	0	0	0	0	109.7	P460 L461 S467 S468	P460-V464 WeakPolarHBondContact O-CG2 3.31Å; P460-V464 PolarHBondContact O-N 3.07Å; L461-V464 PolarHBondContact O-N 3.38Å; V464-S467 PolarHBondContact O-N 2.64Å; V464-S468 PolarHBondContact O-N 3.43Å; V464-S468 PolarHBondContact O-OG 3.33Å
465	V	88.6	Confident	87.2	Confident	53 Å²	53	54 Å²	54	32%	0.321	33%	0.327	S	S	.	.	H	α-helix	trans	-60.7	-50.5	177.8	174.7	0	0	0	0	111.2	L102 L461 S462 S467 S468 I469	L102-V465 HydrophobicContact CD1-CG1 4Å; L461-V465 WeakPolarHBondContact O-CG2 3.28Å; L461-V465 PolarHBondContact O-N 2.92Å; S462-V465 PolarHBondContact O-N 3.21Å; V465-S467 VanDerWaalsContact C-N 3.28Å; V465-S467 PolarHBondContact O-N 2.93Å; V465-S468 WeakPolarHBondContact O-CB 3.46Å; V465-S468 PolarHBondContact O-N 3.1Å; V465-S468 VanDerWaalsContact O-N 3.09Å; V465-I469 HydrophobicContact CG1-CD1 4.07Å; V465-I469 VanDerWaalsContact O-CG1 3.29Å; V465-I469 WeakPolarHBondContact O-CG1 3.39Å; V465-I469 PolarHBondContact O-N 3.19Å
466	T	86.8	Confident	87.2	Confident	2 Å²	2	48.8 Å²	48.8	1%	0.012	30%	0.303	C	S	.	.	H	α-helix	trans	-61.6	-36.3	178.7	53.8	0	0	0	0	112.3	L106 L444 S462 K463 I469 M470 H519	L106-T466 HydrophobicContact CD1-CG2 3.76Å; L444-T466 HydrophobicContact CD2-CG2 3.44Å; L444-T466 VanDerWaalsContact CD2-CG2 3.44Å; S462-T466 VanDerWaalsContact O-CG2 3.31Å; S462-T466 WeakPolarHBondContact O-CG2 3.17Å; S462-T466 PolarHBondContact O-N 3.23Å; S462-T466 PolarHBondContact O-OG1 3.15Å; S462-T466 VanDerWaalsContact O-OG1 3.08Å; K463-T466 VanDerWaalsContact CA-OG1 3.31Å; K463-T466 WeakPolarHBondContact CA-OG1 3.23Å; K463-T466 PolarHBondContact O-OG1 2.72Å; K463-T466 VanDerWaalsContact O-OG1 3.05Å; T466-I469 PolarHBondContact O-N 3.45Å; T466-M470 WeakPolarHBondContact O-CB 2.93Å; T466-M470 PolarHBondContact O-N 2.93Å; T466-H519 PolarHBondContact OG1-NE2 3.29Å
467	S	87.9	Confident	87.1	Confident	44 Å²	44	47.8 Å²	47.8	31%	0.308	30%	0.299	S	S	.	.	H	α-helix	trans	-65.7	-40.1	173.4	-168.9	0	0	0	0	112.3	K463 V464 V465 I469 M470 V471	K463-S467 WeakPolarHBondContact O-CB 3.45Å; K463-S467 PolarHBondContact O-N 3.29Å; V464-S467 PolarHBondContact O-N 2.64Å; V465-S467 VanDerWaalsContact C-N 3.28Å; V465-S467 PolarHBondContact O-N 2.93Å; S467-I469 VanDerWaalsContact C-N 3.34Å; S467-M470 WeakPolarHBondContact O-CB 3.16Å; S467-M470 PolarHBondContact O-N 2.99Å; S467-V471 WeakPolarHBondContact O-CG2 3.49Å; S467-V471 PolarHBondContact O-N 2.86Å
468	S	90.5	Very high	87	Confident	70 Å²	70	51.1 Å²	51.1	49%	0.49	31%	0.312	S	S	.	.	H	α-helix	trans	-62.8	-41	174.5	-63.2	0	0	0	0	111.8	V464 V465 V471 L472	V464-S468 PolarHBondContact O-N 3.43Å; V464-S468 PolarHBondContact O-OG 3.33Å; V465-S468 WeakPolarHBondContact O-CB 3.46Å; V465-S468 PolarHBondContact O-N 3.1Å; V465-S468 VanDerWaalsContact O-N 3.09Å; S468-V471 PolarHBondContact O-N 3Å; S468-L472 WeakPolarHBondContact O-CB 3.45Å; S468-L472 PolarHBondContact O-N 3.37Å
469	I	89.3	Confident	86.9	Confident	10 Å²	10	55 Å²	55	5%	0.051	33%	0.327	C	S	.	.	H	α-helix	trans	-62	-46.9	175.8	-61.3	172.8	0	0	0	110.5	L99 V440 L444 V465 T466 S467 V471 L472 V473	L99-I469 HydrophobicContact CD1-CB 4.22Å; L99-I469 HydrophobicContact CD1-CD1 3.26Å; L99-I469 HydrophobicContact CD1-CG1 3.32Å; L99-I469 HydrophobicContact CD1-CG2 3.93Å; V440-I469 HydrophobicContact CG1-CG2 3.89Å; L444-I469 HydrophobicContact CD1-CB 4.41Å; L444-I469 HydrophobicContact CD1-CG2 4.24Å; V465-I469 HydrophobicContact CG1-CD1 4.07Å; V465-I469 VanDerWaalsContact O-CG1 3.29Å; V465-I469 WeakPolarHBondContact O-CG1 3.39Å; V465-I469 PolarHBondContact O-N 3.19Å; T466-I469 PolarHBondContact O-N 3.45Å; S467-I469 VanDerWaalsContact C-N 3.34Å; I469-V471 VanDerWaalsContact C-N 3.34Å; I469-V471 PolarHBondContact O-N 2.75Å; I469-L472 PolarHBondContact O-N 2.96Å; I469-V473 HydrophobicContact CG2-CG2 4.26Å; I469-V473 WeakPolarHBondContact O-CB 3.28Å; I469-V473 WeakPolarHBondContact O-CG2 3.46Å; I469-V473 PolarHBondContact O-N 3.01Å
470	M	89.3	Confident	86.5	Confident	15 Å²	15	54.2 Å²	54.2	7%	0.074	31%	0.313	C	S	.	.	H	α-helix	trans	-55.8	-48.4	176.5	177.5	-179	74.2	0	0	111.4	L441 L444 T466 S467 C474 V512 C515	L441-M470 HydrophobicContact CD2-CB 4.34Å; L441-M470 HydrophobicContact CD2-CG 3.62Å; L441-M470 HydrophobicContact CD2-SD 4.36Å; L444-M470 HydrophobicContact CD1-CB 4.02Å; T466-M470 WeakPolarHBondContact O-CB 2.93Å; T466-M470 PolarHBondContact O-N 2.93Å; S467-M470 WeakPolarHBondContact O-CB 3.16Å; S467-M470 PolarHBondContact O-N 2.99Å; M470-C474 WeakPolarHBondContact O-CB 3.36Å; M470-C474 PolarHBondContact O-N 3.45Å; M470-C474 PolarHBondContact O-SG 3.19Å; M470-V512 HydrophobicContact SD-CG1 4.35Å; M470-C515 HydrophobicContact SD-CB 3.88Å; M470-C515 VanDerWaalsContact SD-SG 3.69Å
471	V	90.4	Very high	86.2	Confident	91 Å²	91	49.8 Å²	49.8	55%	0.552	28%	0.284	S	S	*	.	H	α-helix	trans	-63	-45	179.3	171.3	0	0	0	0	111.2	S467 S468 I469 C474 A475	S467-V471 WeakPolarHBondContact O-CG2 3.49Å; S467-V471 PolarHBondContact O-N 2.86Å; S468-V471 PolarHBondContact O-N 3Å; I469-V471 VanDerWaalsContact C-N 3.34Å; I469-V471 PolarHBondContact O-N 2.75Å; V471-C474 PolarHBondContact O-N 3.44Å; V471-A475 VanDerWaalsContact O-CB 3.31Å; V471-A475 WeakPolarHBondContact O-CB 3.28Å; V471-A475 PolarHBondContact O-N 3.43Å
472	L	88.5	Confident	85.9	Confident	82 Å²	82	47.9 Å²	47.9	43%	0.429	28%	0.278	S	S	.	.	H	α-helix	trans	-60	-50.5	178.8	178.1	64.1	0	0	0	111.6	L99 S468 I469 C474 A475 I476	L99-L472 HydrophobicContact CD2-CD2 4.04Å; S468-L472 WeakPolarHBondContact O-CB 3.45Å; S468-L472 PolarHBondContact O-N 3.37Å; I469-L472 PolarHBondContact O-N 2.96Å; L472-C474 VanDerWaalsContact C-N 3.33Å; L472-C474 PolarHBondContact O-N 3.24Å; L472-A475 PolarHBondContact O-N 2.94Å; L472-I476 HydrophobicContact CD1-CD1 3.93Å; L472-I476 HydrophobicContact CD1-CG1 4.33Å; L472-I476 HydrophobicContact CG-CD1 3.98Å; L472-I476 WeakPolarHBondContact O-CG1 3.38Å; L472-I476 PolarHBondContact O-N 2.71Å
473	V	87.3	Confident	85.5	Confident	3 Å²	3	48.8 Å²	48.8	2%	0.018	28%	0.284	C	S	.	.	H	α-helix	trans	-62.2	-42.5	-179.9	170.3	0	0	0	0	110.7	L436 P437 V440 I469 N477	L436-V473 HydrophobicContact CD2-CG1 4.4Å; L436-V473 HydrophobicContact CD2-CG2 4.05Å; L436-V473 HydrophobicContact CG-CG1 4.24Å; L436-V473 HydrophobicContact CG-CG2 4.45Å; P437-V473 HydrophobicContact CB-CG1 3.97Å; P437-V473 HydrophobicContact CG-CG1 3.67Å; V440-V473 HydrophobicContact CG1-CG2 4.4Å; I469-V473 HydrophobicContact CG2-CG2 4.26Å; I469-V473 WeakPolarHBondContact O-CB 3.28Å; I469-V473 WeakPolarHBondContact O-CG2 3.46Å; I469-V473 PolarHBondContact O-N 3.01Å; V473-N477 WeakPolarHBondContact O-CB 3.23Å; V473-N477 PolarHBondContact O-N 2.79Å; V473-N477 VanDerWaalsContact O-N 3.14Å; V473-N477 PolarHBondContact O-ND2 3.48Å
474	C	86.6	Confident	84.9	Confident	40 Å²	40	52 Å²	52	27%	0.27	30%	0.295	S	S	.	.	H	α-helix	trans	-64.7	-40.5	175.9	-66.6	0	0	0	0	112.2	M470 V471 L472 N477 L478 V512	M470-C474 WeakPolarHBondContact O-CB 3.36Å; M470-C474 PolarHBondContact O-N 3.45Å; M470-C474 PolarHBondContact O-SG 3.19Å; V471-C474 PolarHBondContact O-N 3.44Å; L472-C474 VanDerWaalsContact C-N 3.33Å; L472-C474 PolarHBondContact O-N 3.24Å; C474-N477 PolarHBondContact O-N 2.99Å; C474-L478 VanDerWaalsContact O-CB 3.24Å; C474-L478 WeakPolarHBondContact O-CB 3.05Å; C474-L478 PolarHBondContact O-N 3.19Å; C474-V512 VanDerWaalsContact SG-CG2 3.55Å
475	A	87.8	Confident	84.1	Confident	55 Å²	55	49.6 Å²	49.6	46%	0.455	28%	0.279	S	S	.	.	H	α-helix	trans	-65.3	-45.4	-179.9	0	0	0	0	0	112.1	V471 L472 N477 L478 Y479	V471-A475 VanDerWaalsContact O-CB 3.31Å; V471-A475 WeakPolarHBondContact O-CB 3.28Å; V471-A475 PolarHBondContact O-N 3.43Å; L472-A475 PolarHBondContact O-N 2.94Å; A475-N477 PolarHBondContact O-N 3.4Å; A475-L478 PolarHBondContact O-N 3.23Å; A475-Y479 WeakPolarHBondContact O-CB 3.5Å; A475-Y479 PolarHBondContact O-N 3Å
476	I	83.1	Confident	83.4	Confident	24 Å²	24	52 Å²	52	12%	0.123	30%	0.296	C	S	.	.	H	α-helix	trans	-59.6	-47.4	176.6	-70.7	169.9	0	0	0	110.6	V242 V245 L472 Y479 F480	V242-I476 HydrophobicContact CG1-CG2 3.47Å; V242-I476 VanDerWaalsContact CG1-CG2 3.47Å; V245-I476 HydrophobicContact CG1-CD1 4.36Å; L472-I476 HydrophobicContact CD1-CD1 3.93Å; L472-I476 HydrophobicContact CD1-CG1 4.33Å; L472-I476 HydrophobicContact CG-CD1 3.98Å; L472-I476 WeakPolarHBondContact O-CG1 3.38Å; L472-I476 PolarHBondContact O-N 2.71Å; I476-Y479 WeakPolarHBondContact O-CB 3.44Å; I476-Y479 PolarHBondContact O-N 3.03Å; I476-F480 HydrophobicContact CG2-CD2 4Å; I476-F480 HydrophobicContact CG2-CE2 4.04Å; I476-F480 WeakPolarHBondContact O-CD2 3.28Å; I476-F480 PolarHBondContact O-N 2.95Å
477	N	84.4	Confident	82.6	Confident	5 Å²	5	55.4 Å²	55.4	3%	0.027	32%	0.32	C	S	.	.	H	α-helix	trans	-69.5	-38.9	-177.9	-80.1	-77.6	0	0	0	112.6	S433 L434 P437 V473 C474 A475 Y479 F480 V481 Y504	S433-N477 PolarHBondContact O-ND2 3.22Å; S433-N477 PolarHBondContact O-OD1 3.49Å; S433-N477 VanDerWaalsContact O-OD1 3.07Å; L434-N477 WeakPolarHBondContact CA-OD1 3.49Å; L434-N477 PolarHBondContact O-OD1 2.74Å; P437-N477 HydrophobicContact CG-CB 4.22Å; P437-N477 VanDerWaalsContact CG-ND2 3.32Å; P437-N477 WeakPolarHBondContact CG-ND2 3.42Å; V473-N477 WeakPolarHBondContact O-CB 3.23Å; V473-N477 PolarHBondContact O-N 2.79Å; V473-N477 VanDerWaalsContact O-N 3.14Å; V473-N477 PolarHBondContact O-ND2 3.48Å; C474-N477 PolarHBondContact O-N 2.99Å; A475-N477 PolarHBondContact O-N 3.4Å; N477-Y479 VanDerWaalsContact C-N 3.34Å; N477-F480 PolarHBondContact O-N 2.83Å; N477-V481 WeakPolarHBondContact O-CG2 3.48Å; N477-V481 PolarHBondContact O-N 3.38Å; N477-Y504 WeakPolarHBondContact CB-OH 3.39Å; N477-Y504 PolarHBondContact OD1-OH 3.14Å
478	L	84	Confident	81.7	Confident	97 Å²	97	55.2 Å²	55.2	51%	0.508	32%	0.315	S	S	.	.	H	α-helix	trans	-63.1	-42.8	173.9	-174.7	64.8	0	0	0	111.2	C474 A475 F480 V481 V482 L505	C474-L478 VanDerWaalsContact O-CB 3.24Å; C474-L478 WeakPolarHBondContact O-CB 3.05Å; C474-L478 PolarHBondContact O-N 3.19Å; A475-L478 PolarHBondContact O-N 3.23Å; L478-F480 PolarHBondContact O-N 3.28Å; L478-V481 PolarHBondContact O-N 3.45Å; L478-V482 HydrophobicContact CD1-CG2 4.35Å; L478-V482 HydrophobicContact CG-CG2 4.5Å; L478-V482 WeakPolarHBondContact O-CB 3.42Å; L478-V482 VanDerWaalsContact O-CG2 3.27Å; L478-V482 WeakPolarHBondContact O-CG2 3.35Å; L478-V482 PolarHBondContact O-N 3.46Å; L478-L505 HydrophobicContact CD1-CD2 4.46Å
479	Y	83.4	Confident	80.6	Confident	89 Å²	89	57.6 Å²	57.6	35%	0.349	33%	0.329	S	S	.	.	H	α-helix	trans	-57.8	-47.1	175	175.9	-96.1	0	0	0	111.5	H235 A475 I476 N477 V482 S483	H235-Y479 PolarHBondContact NE2-OH 3.13Å; A475-Y479 WeakPolarHBondContact O-CB 3.5Å; A475-Y479 PolarHBondContact O-N 3Å; I476-Y479 WeakPolarHBondContact O-CB 3.44Å; I476-Y479 PolarHBondContact O-N 3.03Å; N477-Y479 VanDerWaalsContact C-N 3.34Å; Y479-V482 PolarHBondContact O-N 3.48Å; Y479-S483 VanDerWaalsContact O-CB 3.26Å; Y479-S483 WeakPolarHBondContact O-CB 3.42Å; Y479-S483 PolarHBondContact O-N 3.47Å
480	F	76.9	Confident	79.8	Confident	22 Å²	22	62.8 Å²	62.8	10%	0.096	35%	0.353	C	S	.	.	H	α-helix	trans	-60.7	-48	177.4	-91.2	-62.7	0	0	0	113.1	L239 V242 V430 L434 I476 N477 L478 V482 S483 Y484	L239-F480 HydrophobicContact CD2-CE1 4.19Å; V242-F480 HydrophobicContact CB-CE2 4.29Å; V242-F480 HydrophobicContact CB-CZ 4.27Å; V242-F480 HydrophobicContact CG1-CD2 4.16Å; V242-F480 HydrophobicContact CG1-CE2 3.12Å; V242-F480 HydrophobicContact CG1-CZ 3.49Å; V242-F480 VanDerWaalsContact CG1-CZ 3.49Å; V430-F480 HydrophobicContact CG1-CD1 4.39Å; V430-F480 HydrophobicContact CG1-CE1 4.07Å; V430-F480 HydrophobicContact CG1-CZ 4.39Å; L434-F480 HydrophobicContact CD2-CB 3.92Å; L434-F480 HydrophobicContact CD2-CG 4.5Å; I476-F480 HydrophobicContact CG2-CD2 4Å; I476-F480 HydrophobicContact CG2-CE2 4.04Å; I476-F480 WeakPolarHBondContact O-CD2 3.28Å; I476-F480 PolarHBondContact O-N 2.95Å; N477-F480 PolarHBondContact O-N 2.83Å; L478-F480 PolarHBondContact O-N 3.28Å; F480-V482 VanDerWaalsContact C-N 3.29Å; F480-V482 PolarHBondContact O-N 3.12Å; F480-S483 PolarHBondContact O-N 3.25Å; F480-Y484 WeakPolarHBondContact O-CB 3.41Å; F480-Y484 PolarHBondContact O-N 3.44Å
481	V	78.4	Confident	78.9	Confident	19 Å²	19	67.4 Å²	67.4	12%	0.115	38%	0.384	C	S	.	.	H	α-helix	trans	-59.8	-44.1	-179.8	172.8	0	0	0	0	110.4	N477 L478 L485 A501 Y504 L505	N477-V481 WeakPolarHBondContact O-CG2 3.48Å; N477-V481 PolarHBondContact O-N 3.38Å; L478-V481 PolarHBondContact O-N 3.45Å; V481-L485 HydrophobicContact CG1-CD1 4.12Å; V481-L485 WeakPolarHBondContact O-CB 3.25Å; V481-L485 PolarHBondContact O-N 3.05Å; V481-L485 VanDerWaalsContact O-N 3.13Å; V481-A501 HydrophobicContact CG1-CB 4.16Å; V481-Y504 HydrophobicContact CG2-CD1 4.17Å; V481-Y504 HydrophobicContact CG2-CE1 4.07Å; V481-L505 HydrophobicContact CG1-CD1 4.37Å
482	V	81.6	Confident	77.9	Confident	94 Å²	94	67.2 Å²	67.2	57%	0.57	39%	0.392	S	S	*	.	H	α-helix	trans	-69.6	-37.1	179.7	173.7	0	0	0	0	112.2	L478 Y479 F480 P486	L478-V482 HydrophobicContact CD1-CG2 4.35Å; L478-V482 HydrophobicContact CG-CG2 4.5Å; L478-V482 WeakPolarHBondContact O-CB 3.42Å; L478-V482 VanDerWaalsContact O-CG2 3.27Å; L478-V482 WeakPolarHBondContact O-CG2 3.35Å; L478-V482 PolarHBondContact O-N 3.46Å; Y479-V482 PolarHBondContact O-N 3.48Å; F480-V482 VanDerWaalsContact C-N 3.29Å; F480-V482 PolarHBondContact O-N 3.12Å; V482-P486 WeakPolarHBondContact O-CD 3.4Å; V482-P486 VanDerWaalsContact O-CG 3.28Å; V482-P486 WeakPolarHBondContact O-CG 3.33Å
483	S	77.1	Confident	77.1	Confident	49 Å²	49	70.2 Å²	70.2	34%	0.343	40%	0.398	S	S	.	.	H	α-helix	trans	-74.8	-33.1	178.6	-172.8	0	0	0	0	112.4	Y479 F480	Y479-S483 VanDerWaalsContact O-CB 3.26Å; Y479-S483 WeakPolarHBondContact O-CB 3.42Å; Y479-S483 PolarHBondContact O-N 3.47Å; F480-S483 PolarHBondContact O-N 3.25Å
484	Y	73	Confident	76.6	Confident	134 Å²	134	74.8 Å²	74.8	53%	0.525	42%	0.418	S	S	.	.	H	α-helix	trans	-84	-41.2	-173.7	-167.6	-99.4	0	0	0	112.6	F480 S487 L488	F480-Y484 WeakPolarHBondContact O-CB 3.41Å; F480-Y484 PolarHBondContact O-N 3.44Å; Y484-S487 PolarHBondContact O-N 3.23Å; Y484-S487 PolarHBondContact O-OG 3.31Å; Y484-L488 HydrophobicContact CE1-CD2 3.88Å; Y484-L488 HydrophobicContact CE1-CG 4.43Å
485	L	72.3	Confident	76.2	Confident	43 Å²	43	75.2 Å²	75.2	23%	0.225	43%	0.429	C	S	.	.	G	3₁₀ helix	trans	-50.7	-45.7	-179.6	-118.7	84.1	0	0	0	114	V481 S487 F494 A501	V481-L485 HydrophobicContact CG1-CD1 4.12Å; V481-L485 WeakPolarHBondContact O-CB 3.25Å; V481-L485 PolarHBondContact O-N 3.05Å; V481-L485 VanDerWaalsContact O-N 3.13Å; L485-S487 VanDerWaalsContact C-N 3.29Å; L485-S487 PolarHBondContact O-N 3.02Å; L485-F494 HydrophobicContact CD2-CE2 4.33Å; L485-F494 HydrophobicContact CD2-CZ 4.16Å; L485-A501 HydrophobicContact CD1-CB 3.79Å
486	P	72.6	Confident	75.8	Confident	104 Å²	104	77.8 Å²	77.8	68%	0.675	44%	0.435	S	S	*	.	G	3₁₀ helix	trans	-72.6	-18.1	180	-19.8	33.8	0	0	0	114.2	V482 L488	V482-P486 WeakPolarHBondContact O-CD 3.4Å; V482-P486 VanDerWaalsContact O-CG 3.28Å; V482-P486 WeakPolarHBondContact O-CG 3.33Å; P486-L488 VanDerWaalsContact C-N 3.33Å
487	S	69.7	Low	75.6	Confident	74 Å²	74	77.8 Å²	77.8	52%	0.517	44%	0.438	S	S	.	.	G	3₁₀ helix	trans	-85.2	-3.2	-175.6	70.4	0	0	0	0	114	Y484 L485	Y484-S487 PolarHBondContact O-N 3.23Å; Y484-S487 PolarHBondContact O-OG 3.31Å; L485-S487 VanDerWaalsContact C-N 3.29Å; L485-S487 PolarHBondContact O-N 3.02Å
488	L	70	Confident	75.4	Confident	40 Å²	40	79 Å²	79	21%	0.209	45%	0.45	C	S	.	.			trans	-72.4	127.3	-177.1	-72.4	169.8	0	0	0	111.9	Y484 P486 H490 A497	Y484-L488 HydrophobicContact CE1-CD2 3.88Å; Y484-L488 HydrophobicContact CE1-CG 4.43Å; P486-L488 VanDerWaalsContact C-N 3.33Å; L488-H490 VanDerWaalsContact C-N 3.33Å; L488-H490 PolarHBondContact O-N 2.83Å; L488-A497 HydrophobicContact CD1-CB 3.43Å; L488-A497 VanDerWaalsContact CD1-CB 3.43Å
489	P	67	Low	75.4	Confident	119 Å²	119	80 Å²	80	77%	0.773	46%	0.455	S	S	*	.	S	Bend	trans	-74.5	-14.6	-168.3	26.5	-34.2	0	0	0	115
490	H	72	Confident	75.5	Confident	120 Å²	120	80.8 Å²	80.8	56%	0.556	46%	0.464	S	S	*	.			trans	-137	132.2	-174.1	-99.7	-34.1	0	0	0	113.4	L488 A492 Y493	L488-H490 VanDerWaalsContact C-N 3.33Å; L488-H490 PolarHBondContact O-N 2.83Å; H490-A492 PolarHBondContact O-N 3.45Å; H490-Y493 HydrophobicContact CB-CD2 3.61Å; H490-Y493 HydrophobicContact CB-CE2 4.07Å; H490-Y493 PolarHBondContact O-N 3.42Å; H490-Y493 VanDerWaalsContact O-N 3.13Å
491	P	70.4	Confident	75.8	Confident	111 Å²	111	80.4 Å²	80.4	72%	0.721	47%	0.465	S	S	*	.	H	α-helix	trans	-66.2	-21.2	-175.7	25.3	-33.4	0	0	0	113.8	F494	P491-F494 VanDerWaalsContact O-CB 3.25Å; P491-F494 WeakPolarHBondContact O-CB 3.46Å; P491-F494 PolarHBondContact O-N 3.27Å
492	A	69.1	Low	76.1	Confident	87 Å²	87	82.4 Å²	82.4	72%	0.719	48%	0.484	S	S	*	.	H	α-helix	trans	-69.3	-34.4	175	0	0	0	0	0	112.8	H490 F494	H490-A492 PolarHBondContact O-N 3.45Å; A492-F494 VanDerWaalsContact C-N 3.28Å
493	Y	71.6	Confident	76.4	Confident	145 Å²	145	80.8 Å²	80.8	57%	0.569	48%	0.48	S	S	*	.	H	α-helix	trans	-76.3	-19.4	174.3	-65	-74.1	0	0	0	112.3	H490 G495 L496 A497	H490-Y493 HydrophobicContact CB-CD2 3.61Å; H490-Y493 HydrophobicContact CB-CE2 4.07Å; H490-Y493 PolarHBondContact O-N 3.42Å; H490-Y493 VanDerWaalsContact O-N 3.13Å; Y493-G495 VanDerWaalsContact C-N 3.34Å; Y493-G495 PolarHBondContact O-N 3.35Å; Y493-L496 PolarHBondContact O-N 2.83Å; Y493-A497 WeakPolarHBondContact O-CB 3.4Å; Y493-A497 PolarHBondContact O-N 3.04Å
494	F	76.8	Confident	76.9	Confident	100 Å²	100	80.1 Å²	80.1	44%	0.439	47%	0.471	S	S	.	.	H	α-helix	trans	-61.7	-41.7	-179.9	-165.3	-93	0	0	0	111.9	L485 P491 A492 A498	L485-F494 HydrophobicContact CD2-CE2 4.33Å; L485-F494 HydrophobicContact CD2-CZ 4.16Å; P491-F494 VanDerWaalsContact O-CB 3.25Å; P491-F494 WeakPolarHBondContact O-CB 3.46Å; P491-F494 PolarHBondContact O-N 3.27Å; A492-F494 VanDerWaalsContact C-N 3.28Å; F494-A498 WeakPolarHBondContact O-CB 3.22Å; F494-A498 PolarHBondContact O-N 3.15Å
495	G	78.3	Confident	77.6	Confident	49 Å²	49	76.7 Å²	76.7	51%	0.505	46%	0.461	S	S	.	.	H	α-helix	trans	-63.8	-46	178.6	0	0	0	0	0	113.2	Y493 L499	Y493-G495 VanDerWaalsContact C-N 3.34Å; Y493-G495 PolarHBondContact O-N 3.35Å; G495-L499 WeakPolarHBondContact O-CB 3.26Å; G495-L499 PolarHBondContact O-N 3.31Å
496	L	80.1	Confident	78.5	Confident	108 Å²	108	76.4 Å²	76.4	57%	0.565	47%	0.468	S	S	*	.	H	α-helix	trans	-67.5	-45.8	177.8	-179.8	64.3	0	0	0	111.5	Y493 A498 L499 L500	Y493-L496 PolarHBondContact O-N 2.83Å; L496-A498 PolarHBondContact O-N 3.37Å; L496-L499 PolarHBondContact O-N 3.5Å; L496-L500 HydrophobicContact CD1-CD1 4.49Å; L496-L500 HydrophobicContact CG-CD1 4.23Å; L496-L500 WeakPolarHBondContact O-CG 3.26Å; L496-L500 PolarHBondContact O-N 3.08Å
497	A	79.9	Confident	79.3	Confident	24 Å²	24	72.1 Å²	72.1	20%	0.198	44%	0.44	C	S	.	.	H	α-helix	trans	-64.3	-39.6	178.4	0	0	0	0	0	111.8	L488 Y493 L500 A501	L488-A497 HydrophobicContact CD1-CB 3.43Å; L488-A497 VanDerWaalsContact CD1-CB 3.43Å; Y493-A497 WeakPolarHBondContact O-CB 3.4Å; Y493-A497 PolarHBondContact O-N 3.04Å; A497-L500 PolarHBondContact O-N 3.43Å; A497-A501 VanDerWaalsContact O-CB 3.23Å; A497-A501 WeakPolarHBondContact O-CB 3.18Å; A497-A501 PolarHBondContact O-N 3.24Å
498	A	79.7	Confident	80.2	Confident	32 Å²	32	69.3 Å²	69.3	26%	0.264	42%	0.42	S	S	.	.	H	α-helix	trans	-65.1	-39	175	0	0	0	0	0	111.9	F494 L496 A501 A502	F494-A498 WeakPolarHBondContact O-CB 3.22Å; F494-A498 PolarHBondContact O-N 3.15Å; L496-A498 PolarHBondContact O-N 3.37Å; A498-A501 PolarHBondContact O-N 3.42Å; A498-A502 VanDerWaalsContact O-CB 3.28Å; A498-A502 WeakPolarHBondContact O-CB 3.46Å; A498-A502 PolarHBondContact O-N 3.4Å
499	L	84.6	Confident	81.1	Confident	117 Å²	117	71.6 Å²	71.6	61%	0.613	44%	0.436	S	S	*	.	H	α-helix	trans	-66.1	-43.7	175.8	-173.8	144.1	0	0	0	111.7	G495 L496 A502 A503	G495-L499 WeakPolarHBondContact O-CB 3.26Å; G495-L499 PolarHBondContact O-N 3.31Å; L496-L499 PolarHBondContact O-N 3.5Å; L499-A502 PolarHBondContact O-N 3.49Å; L499-A503 WeakPolarHBondContact O-CB 3.34Å; L499-A503 PolarHBondContact O-N 2.73Å
500	L	83.9	Confident	82.1	Confident	105 Å²	105	68.1 Å²	68.1	55%	0.55	41%	0.408	S	S	.	.	H	α-helix	trans	-63.6	-43	174.8	-71.1	172	0	0	0	111.6	L496 A497 A503 Y504	L496-L500 HydrophobicContact CD1-CD1 4.49Å; L496-L500 HydrophobicContact CG-CD1 4.23Å; L496-L500 WeakPolarHBondContact O-CG 3.26Å; L496-L500 PolarHBondContact O-N 3.08Å; A497-L500 PolarHBondContact O-N 3.43Å; L500-A503 PolarHBondContact O-N 2.95Å; L500-Y504 VanDerWaalsContact O-CB 3.28Å; L500-Y504 WeakPolarHBondContact O-CB 3.34Å; L500-Y504 PolarHBondContact O-N 2.7Å
501	A	83.4	Confident	82.9	Confident	15 Å²	15	62.5 Å²	62.5	12%	0.124	38%	0.381	C	S	.	.	H	α-helix	trans	-63.4	-40.5	175.4	0	0	0	0	0	111.7	V481 L485 A497 A498 Y504 L505	V481-A501 HydrophobicContact CG1-CB 4.16Å; L485-A501 HydrophobicContact CD1-CB 3.79Å; A497-A501 VanDerWaalsContact O-CB 3.23Å; A497-A501 WeakPolarHBondContact O-CB 3.18Å; A497-A501 PolarHBondContact O-N 3.24Å; A498-A501 PolarHBondContact O-N 3.42Å; A501-Y504 WeakPolarHBondContact O-CB 3.37Å; A501-Y504 PolarHBondContact O-N 3.13Å; A501-L505 WeakPolarHBondContact O-CB 3.47Å; A501-L505 VanDerWaalsContact O-CG 3.24Å; A501-L505 WeakPolarHBondContact O-CG 2.97Å; A501-L505 PolarHBondContact O-N 3.1Å
502	A	85.1	Confident	83.8	Confident	61 Å²	61	59 Å²	59	50%	0.504	36%	0.358	S	S	.	.	H	α-helix	trans	-64.6	-42.1	175.3	0	0	0	0	0	111.9	A498 L499 L505 G506	A498-A502 VanDerWaalsContact O-CB 3.28Å; A498-A502 WeakPolarHBondContact O-CB 3.46Å; A498-A502 PolarHBondContact O-N 3.4Å; L499-A502 PolarHBondContact O-N 3.49Å; A502-L505 PolarHBondContact O-N 2.05Å; A502-G506 PolarHBondContact O-N 3.38Å
503	A	87.1	Confident	84.6	Confident	60 Å²	60	60 Å²	60	50%	0.496	34%	0.343	S	S	.	.	H	α-helix	trans	-63.4	-43.8	174.4	0	0	0	0	0	111.8	L499 L500 G506 L507	L499-A503 WeakPolarHBondContact O-CB 3.34Å; L499-A503 PolarHBondContact O-N 2.73Å; L500-A503 PolarHBondContact O-N 2.95Å; A503-G506 PolarHBondContact O-N 2.61Å; A503-L507 PolarHBondContact O-N 3.34Å
504	Y	88.5	Confident	85.1	Confident	34 Å²	34	53 Å²	53	13%	0.133	32%	0.316	C	S	.	.	H	α-helix	trans	-59.5	-48.9	175.4	173.1	-87.5	0	0	0	112.1	L434 F438 N477 V481 L500 A501 L507 S508	L434-Y504 WeakPolarHBondContact O-CE2 3.46Å; L434-Y504 PolarHBondContact O-OH 3.41Å; F438-Y504 HydrophobicContact CD2-CE2 4.46Å; F438-Y504 AromaticContact CE2-CD2 3.55Å; F438-Y504 HydrophobicContact CE2-CD2 3.55Å; F438-Y504 AromaticContact CE2-CE2 3.32Å; F438-Y504 HydrophobicContact CE2-CE2 3.32Å; F438-Y504 AromaticContact CZ-CD2 3.37Å; F438-Y504 HydrophobicContact CZ-CD2 3.37Å; F438-Y504 AromaticContact CZ-CE2 3.38Å; F438-Y504 HydrophobicContact CZ-CE2 3.38Å; F438-Y504 HydrophobicContact CZ-CG 4.22Å; N477-Y504 WeakPolarHBondContact CB-OH 3.39Å; N477-Y504 PolarHBondContact OD1-OH 3.14Å; V481-Y504 HydrophobicContact CG2-CD1 4.17Å; V481-Y504 HydrophobicContact CG2-CE1 4.07Å; L500-Y504 VanDerWaalsContact O-CB 3.28Å; L500-Y504 WeakPolarHBondContact O-CB 3.34Å; L500-Y504 PolarHBondContact O-N 2.7Å; A501-Y504 WeakPolarHBondContact O-CB 3.37Å; A501-Y504 PolarHBondContact O-N 3.13Å; Y504-L507 PolarHBondContact O-N 3.37Å; Y504-S508 VanDerWaalsContact O-CB 3.31Å; Y504-S508 WeakPolarHBondContact O-CB 3.37Å; Y504-S508 PolarHBondContact O-N 3.2Å; Y504-S508 PolarHBondContact O-OG 3.13Å
505	L	88.1	Confident	85.4	Confident	63 Å²	63	48.3 Å²	48.3	33%	0.33	30%	0.295	S	S	.	.	H	α-helix	trans	-66.3	-39.6	177.8	-71.3	173.4	0	0	0	110.9	L478 V481 A501 A502 S508 T509	L478-L505 HydrophobicContact CD1-CD2 4.46Å; V481-L505 HydrophobicContact CG1-CD1 4.37Å; A501-L505 WeakPolarHBondContact O-CB 3.47Å; A501-L505 VanDerWaalsContact O-CG 3.24Å; A501-L505 WeakPolarHBondContact O-CG 2.97Å; A501-L505 PolarHBondContact O-N 3.1Å; A502-L505 PolarHBondContact O-N 2.05Å; L505-S508 PolarHBondContact O-N 3.19Å; L505-T509 WeakPolarHBondContact O-CB 3.2Å; L505-T509 VanDerWaalsContact O-CG2 3.27Å; L505-T509 WeakPolarHBondContact O-CG2 3.43Å; L505-T509 PolarHBondContact O-N 2.93Å; L505-T509 PolarHBondContact O-OG1 3Å
506	G	89.6	Confident	85.7	Confident	36 Å²	36	47.6 Å²	47.6	37%	0.371	28%	0.282	S	S	.	.	H	α-helix	trans	-60.1	-46.6	175.2	0	0	0	0	0	112.5	A502 A503 T509 Y510	A502-G506 PolarHBondContact O-N 3.38Å; A503-G506 PolarHBondContact O-N 2.61Å; G506-T509 WeakPolarHBondContact CA-OG1 3.31Å; G506-T509 PolarHBondContact O-OG1 3.42Å; G506-Y510 WeakPolarHBondContact O-CB 3.03Å; G506-Y510 PolarHBondContact O-N 3.38Å
507	L	90.1	Very high	85.7	Confident	15 Å²	15	42.8 Å²	42.8	8%	0.079	26%	0.257	C	S	.	.	H	α-helix	trans	-66.6	-42.9	175.5	-175.2	61.8	0	0	0	111.8	P130 L133 T137 F438 A503 Y504 Y510 L511	P130-L507 HydrophobicContact CB-CD1 4.2Å; L133-L507 HydrophobicContact CB-CD1 4.48Å; L133-L507 HydrophobicContact CB-CD2 3.94Å; T137-L507 HydrophobicContact CG2-CD2 4.46Å; F438-L507 HydrophobicContact CD1-CD2 3.89Å; F438-L507 HydrophobicContact CD1-CG 4.17Å; F438-L507 HydrophobicContact CE1-CB 4.06Å; F438-L507 HydrophobicContact CE1-CD2 3.52Å; F438-L507 HydrophobicContact CE1-CG 3.68Å; F438-L507 HydrophobicContact CZ-CD2 4.08Å; A503-L507 PolarHBondContact O-N 3.34Å; Y504-L507 PolarHBondContact O-N 3.37Å; L507-Y510 WeakPolarHBondContact O-CB 3.42Å; L507-Y510 PolarHBondContact O-N 3.22Å; L507-L511 HydrophobicContact CG-CD1 4.5Å; L507-L511 WeakPolarHBondContact O-CG 3.46Å; L507-L511 PolarHBondContact O-N 2.78Å
508	S	88.9	Confident	85.4	Confident	14 Å²	14	42.1 Å²	42.1	10%	0.098	25%	0.251	C	S	.	.	H	α-helix	trans	-63.1	-45.6	179.3	-61.9	0	0	0	0	111.8	Y504 L505 Y510 L511 V512	Y504-S508 VanDerWaalsContact O-CB 3.31Å; Y504-S508 WeakPolarHBondContact O-CB 3.37Å; Y504-S508 PolarHBondContact O-N 3.2Å; Y504-S508 PolarHBondContact O-OG 3.13Å; L505-S508 PolarHBondContact O-N 3.19Å; S508-Y510 PolarHBondContact O-N 3.29Å; S508-L511 PolarHBondContact O-N 3.3Å; S508-V512 VanDerWaalsContact O-CG2 3.3Å; S508-V512 WeakPolarHBondContact O-CG2 3.28Å; S508-V512 PolarHBondContact O-N 2.86Å
509	T	88.9	Confident	85.2	Confident	89 Å²	89	42.4 Å²	42.4	55%	0.546	25%	0.247	S	C	.	.	H	α-helix	trans	-63.2	-39.8	176	49.2	0	0	0	0	112.1	L505 G506 V512 W513	L505-T509 WeakPolarHBondContact O-CB 3.2Å; L505-T509 VanDerWaalsContact O-CG2 3.27Å; L505-T509 WeakPolarHBondContact O-CG2 3.43Å; L505-T509 PolarHBondContact O-N 2.93Å; L505-T509 PolarHBondContact O-OG1 3Å; G506-T509 WeakPolarHBondContact CA-OG1 3.31Å; G506-T509 PolarHBondContact O-OG1 3.42Å; T509-V512 PolarHBondContact O-N 3.24Å; T509-W513 VanDerWaalsContact O-CB 3.29Å; T509-W513 WeakPolarHBondContact O-CB 3.07Å; T509-W513 PolarHBondContact O-N 2.79Å
510	Y	88.8	Confident	84.4	Confident	46 Å²	46	39.1 Å²	39.1	18%	0.18	24%	0.242	C	C	.	.	H	α-helix	trans	-59	-46.1	171.5	174.2	-99.5	0	0	0	112	Y126 P127 P130 G506 L507 S508 W513 T514	Y126-Y510 AromaticContact CD1-CE1 3.78Å; Y126-Y510 HydrophobicContact CD1-CE1 3.78Å; Y126-Y510 AromaticContact CE1-CE1 3.89Å; Y126-Y510 HydrophobicContact CE1-CE1 3.89Å; P127-Y510 VanDerWaalsContact CD-OH 3.31Å; P127-Y510 WeakPolarHBondContact CD-OH 3.48Å; P130-Y510 HydrophobicContact CB-CD1 4.06Å; P130-Y510 HydrophobicContact CB-CE1 3.66Å; P130-Y510 HydrophobicContact CG-CD1 4.21Å; P130-Y510 HydrophobicContact CG-CE1 3.77Å; G506-Y510 WeakPolarHBondContact O-CB 3.03Å; G506-Y510 PolarHBondContact O-N 3.38Å; L507-Y510 WeakPolarHBondContact O-CB 3.42Å; L507-Y510 PolarHBondContact O-N 3.22Å; S508-Y510 PolarHBondContact O-N 3.29Å; Y510-W513 WeakPolarHBondContact O-CB 3.46Å; Y510-W513 PolarHBondContact O-N 3.48Å; Y510-T514 HydrophobicContact CE1-CG2 4.27Å; Y510-T514 HydrophobicContact CE2-CG2 4.34Å; Y510-T514 WeakPolarHBondContact O-CG2 3.41Å; Y510-T514 PolarHBondContact O-N 2.86Å
511	L	88.6	Confident	83.7	Confident	1 Å²	1	35.9 Å²	35.9	1%	0.005	23%	0.23	C	C	.	.	H	α-helix	trans	-66.8	-42.4	178.7	-68.1	177.1	0	0	0	112.2	Y126 F438 L441 P442 L507 S508 W513 T514 C515	Y126-L511 HydrophobicContact CE1-CD2 3.9Å; Y126-L511 HydrophobicContact CE2-CD2 4.16Å; Y126-L511 WeakPolarHBondContact OH-CD2 3.11Å; F438-L511 HydrophobicContact CD1-CD1 3.67Å; F438-L511 HydrophobicContact CE1-CD1 4.33Å; L441-L511 HydrophobicContact CB-CB 3.92Å; L441-L511 HydrophobicContact CD1-CB 3.63Å; L441-L511 HydrophobicContact CD1-CD1 4.42Å; L441-L511 HydrophobicContact CG-CB 4.44Å; P442-L511 HydrophobicContact CG-CD2 4.39Å; L507-L511 HydrophobicContact CG-CD1 4.5Å; L507-L511 WeakPolarHBondContact O-CG 3.46Å; L507-L511 PolarHBondContact O-N 2.78Å; S508-L511 PolarHBondContact O-N 3.3Å; L511-W513 VanDerWaalsContact C-N 3.3Å; L511-W513 PolarHBondContact O-N 3.45Å; L511-T514 WeakPolarHBondContact CA-OG1 3.47Å; L511-T514 PolarHBondContact O-N 3.16Å; L511-T514 PolarHBondContact O-OG1 2.98Å; L511-C515 PolarHBondContact O-N 3.05Å
512	V	88	Confident	82.7	Confident	38 Å²	38	39.6 Å²	39.6	23%	0.23	25%	0.251	C	S	.	.	H	α-helix	trans	-59	-44.1	173.9	170.4	0	0	0	0	110.6	L441 M470 C474 S508 T509 T514 C515 C516	L441-V512 HydrophobicContact CD1-CG2 3.79Å; L441-V512 HydrophobicContact CD2-CG2 4.17Å; M470-V512 HydrophobicContact SD-CG1 4.35Å; C474-V512 VanDerWaalsContact SG-CG2 3.55Å; S508-V512 VanDerWaalsContact O-CG2 3.3Å; S508-V512 WeakPolarHBondContact O-CG2 3.28Å; S508-V512 PolarHBondContact O-N 2.86Å; T509-V512 PolarHBondContact O-N 3.24Å; V512-T514 PolarHBondContact O-N 3Å; V512-C515 WeakPolarHBondContact O-CB 3.37Å; V512-C515 PolarHBondContact O-N 3.04Å; V512-C515 VanDerWaalsContact O-N 3.16Å; V512-C516 PolarHBondContact O-N 3.13Å; V512-C516 PolarHBondContact O-SG 3.46Å; V512-C516 VanDerWaalsContact O-SG 3.36Å
513	W	86.5	Confident	81.4	Confident	107 Å²	107	45.9 Å²	45.9	41%	0.405	27%	0.268	S	S	.	.	H	α-helix	trans	-57	-47.6	175.5	179.6	-96	0	0	0	111.9	T509 Y510 L511 C515 C516 L517 L524	T509-W513 VanDerWaalsContact O-CB 3.29Å; T509-W513 WeakPolarHBondContact O-CB 3.07Å; T509-W513 PolarHBondContact O-N 2.79Å; Y510-W513 WeakPolarHBondContact O-CB 3.46Å; Y510-W513 PolarHBondContact O-N 3.48Å; L511-W513 VanDerWaalsContact C-N 3.3Å; L511-W513 PolarHBondContact O-N 3.45Å; W513-C515 VanDerWaalsContact C-N 3.31Å; W513-C515 PolarHBondContact O-N 2.9Å; W513-C516 PolarHBondContact O-N 3.19Å; W513-L517 WeakPolarHBondContact O-CG 3.4Å; W513-L517 PolarHBondContact O-N 2.69Å; W513-L524 HydrophobicContact CD2-CB 4.49Å; W513-L524 HydrophobicContact CE3-CB 4.41Å; W513-L524 HydrophobicContact CE3-CD1 3.98Å; W513-L524 HydrophobicContact CH2-CB 3.51Å; W513-L524 HydrophobicContact CH2-CD1 4.24Å; W513-L524 HydrophobicContact CH2-CD2 3.49Å; W513-L524 VanDerWaalsContact CH2-CD2 3.49Å; W513-L524 HydrophobicContact CH2-CG 3.89Å; W513-L524 HydrophobicContact CZ2-CB 3.58Å; W513-L524 HydrophobicContact CZ2-CD2 4.43Å; W513-L524 HydrophobicContact CZ2-CG 4.44Å; W513-L524 WeakPolarHBondContact CZ2-O 3.25Å; W513-L524 HydrophobicContact CZ3-CB 3.95Å; W513-L524 HydrophobicContact CZ3-CD1 3.79Å; W513-L524 HydrophobicContact CZ3-CD2 3.53Å; W513-L524 HydrophobicContact CZ3-CG 3.93Å
514	T	82.9	Confident	80.2	Confident	0 Å²	0	45 Å²	45	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-63.5	-36.1	176.4	59.1	0	0	0	0	112.9	Y126 Y510 L511 V512 L517 A518 F532	Y126-T514 HydrophobicContact CE1-CG2 4.18Å; Y126-T514 PolarHBondContact OH-OG1 3.39Å; Y510-T514 HydrophobicContact CE1-CG2 4.27Å; Y510-T514 HydrophobicContact CE2-CG2 4.34Å; Y510-T514 WeakPolarHBondContact O-CG2 3.41Å; Y510-T514 PolarHBondContact O-N 2.86Å; L511-T514 WeakPolarHBondContact CA-OG1 3.47Å; L511-T514 PolarHBondContact O-N 3.16Å; L511-T514 PolarHBondContact O-OG1 2.98Å; V512-T514 PolarHBondContact O-N 3Å; T514-L517 PolarHBondContact O-N 3.43Å; T514-A518 PolarHBondContact O-N 2.98Å; T514-F532 HydrophobicContact CG2-CE2 4.38Å; T514-F532 HydrophobicContact CG2-CZ 4.33Å
515	C	83.3	Confident	78.7	Confident	0 Å²	0	45.2 Å²	45.2	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-66.1	-41.9	175.4	-166.7	0	0	0	0	112	T445 M470 L511 V512 W513 L517 A518 H519	T445-C515 VanDerWaalsContact OG1-CA 3.23Å; T445-C515 WeakPolarHBondContact OG1-CA 3.24Å; T445-C515 VanDerWaalsContact OG1-CB 3.27Å; T445-C515 WeakPolarHBondContact OG1-CB 3.4Å; T445-C515 PolarHBondContact OG1-N 3.37Å; M470-C515 HydrophobicContact SD-CB 3.88Å; M470-C515 VanDerWaalsContact SD-SG 3.69Å; L511-C515 PolarHBondContact O-N 3.05Å; V512-C515 WeakPolarHBondContact O-CB 3.37Å; V512-C515 PolarHBondContact O-N 3.04Å; V512-C515 VanDerWaalsContact O-N 3.16Å; W513-C515 VanDerWaalsContact C-N 3.31Å; W513-C515 PolarHBondContact O-N 2.9Å; C515-L517 VanDerWaalsContact C-N 3.34Å; C515-L517 PolarHBondContact O-N 3.35Å; C515-A518 PolarHBondContact O-N 3.05Å; C515-H519 PolarHBondContact O-N 3.33Å
516	C	82.9	Confident	77.1	Confident	35 Å²	35	48.8 Å²	48.8	24%	0.236	28%	0.278	C	S	.	.	H	α-helix	trans	-62.4	-40.7	175.9	-72.4	0	0	0	0	111.9	V512 W513 H519 G520 A521 L524	V512-C516 PolarHBondContact O-N 3.13Å; V512-C516 PolarHBondContact O-SG 3.46Å; V512-C516 VanDerWaalsContact O-SG 3.36Å; W513-C516 PolarHBondContact O-N 3.19Å; C516-H519 PolarHBondContact O-N 3.02Å; C516-G520 PolarHBondContact O-N 2.82Å; C516-A521 HydrophobicContact CB-CB 4.47Å; C516-A521 VanDerWaalsContact O-CB 3.31Å; C516-A521 WeakPolarHBondContact O-CB 3.39Å; C516-A521 PolarHBondContact O-N 2.82Å; C516-A521 VanDerWaalsContact O-N 3.14Å; C516-L524 HydrophobicContact CB-CD1 4.23Å
517	L	80.4	Confident	75.5	Confident	6 Å²	6	51.6 Å²	51.6	3%	0.031	29%	0.292	C	S	.	.	H	α-helix	trans	-59.7	-47.8	173.4	-72.8	172.5	0	0	0	111.4	W513 T514 C515 H519 G520 L524 A525	W513-L517 WeakPolarHBondContact O-CG 3.4Å; W513-L517 PolarHBondContact O-N 2.69Å; T514-L517 PolarHBondContact O-N 3.43Å; C515-L517 VanDerWaalsContact C-N 3.34Å; C515-L517 PolarHBondContact O-N 3.35Å; L517-H519 VanDerWaalsContact C-N 3.28Å; L517-H519 PolarHBondContact O-N 3.44Å; L517-G520 PolarHBondContact O-N 2.91Å; L517-L524 HydrophobicContact CD2-CB 3.79Å; L517-A525 HydrophobicContact CD2-CB 4.17Å
518	A	74.5	Confident	73.8	Confident	10 Å²	10	54.6 Å²	54.6	8%	0.083	31%	0.314	C	S	.	.	H	α-helix	trans	-63.2	-31.1	177.9	0	0	0	0	0	113.4	T445 M449 T514 C515 G520	T445-A518 HydrophobicContact CG2-CB 3.73Å; T445-A518 WeakPolarHBondContact O-CB 3.25Å; M449-A518 HydrophobicContact CG-CB 3.68Å; T514-A518 PolarHBondContact O-N 2.98Å; C515-A518 PolarHBondContact O-N 3.05Å; A518-G520 PolarHBondContact O-N 3.35Å
519	H	75.5	Confident	72.3	Confident	38 Å²	38	55.5 Å²	55.5	18%	0.176	32%	0.317	C	S	.	.	H	α-helix	trans	-72.8	-12.9	174.5	-74.6	159.4	0	0	0	113.9	S448 T466 C515 C516 L517	S448-H519 PolarHBondContact OG-CD2 2.68Å; S448-H519 PolarHBondContact OG-NE2 3.3Å; T466-H519 PolarHBondContact OG1-NE2 3.29Å; C515-H519 PolarHBondContact O-N 3.33Å; C516-H519 PolarHBondContact O-N 3.02Å; L517-H519 VanDerWaalsContact C-N 3.28Å; L517-H519 PolarHBondContact O-N 3.44Å
520	G	67.5	Low	70.8	Confident	48 Å²	48	55.5 Å²	55.5	50%	0.495	31%	0.31	S	S	.	.	T	Hydrogen-bonded Turn	trans	113.1	13.6	174.4	0	0	0	0	0	114.9	C516 L517 A518 T522	C516-G520 PolarHBondContact O-N 2.82Å; L517-G520 PolarHBondContact O-N 2.91Å; A518-G520 PolarHBondContact O-N 3.35Å; G520-T522 PolarHBondContact O-N 2.73Å
521	A	69.8	Low	69.5	Low	38 Å²	38	56 Å²	56	31%	0.314	31%	0.314	S	S	.	.			trans	-75.1	66.9	173.9	0	0	0	0	0	111.3	C516 F523 L524	C516-A521 HydrophobicContact CB-CB 4.47Å; C516-A521 VanDerWaalsContact O-CB 3.31Å; C516-A521 WeakPolarHBondContact O-CB 3.39Å; C516-A521 PolarHBondContact O-N 2.82Å; C516-A521 VanDerWaalsContact O-N 3.14Å; A521-F523 PolarHBondContact O-N 3.49Å; A521-F523 VanDerWaalsContact O-N 3.14Å; A521-L524 HydrophobicContact CB-CD1 4Å; A521-L524 HydrophobicContact CB-CG 4.33Å; A521-L524 PolarHBondContact O-N 2.88Å
522	T	60.8	Low	68	Low	92 Å²	92	56.2 Å²	56.2	56%	0.564	32%	0.315	S	S	*	.	G	3₁₀ helix	trans	-63.7	-18.6	-174.8	56.2	0	0	0	0	114.1	G520 L524 A525 L533	G520-T522 PolarHBondContact O-N 2.73Å; T522-L524 PolarHBondContact O-N 3.43Å; T522-A525 VanDerWaalsContact O-CB 3.31Å; T522-A525 WeakPolarHBondContact O-CB 3.28Å; T522-A525 PolarHBondContact O-N 3.41Å; T522-A525 VanDerWaalsContact O-N 3.15Å; T522-L533 HydrophobicContact CG2-CD2 4.04Å
523	F	59.4	Low	66.6	Low	194 Å²	194	57.1 Å²	57.1	85%	0.851	32%	0.318	S	S	*	.	G	3₁₀ helix	trans	-59.3	-26.4	171.1	163.4	-104.8	0	0	0	113.3	A521 A525	A521-F523 PolarHBondContact O-N 3.49Å; A521-F523 VanDerWaalsContact O-N 3.14Å; F523-A525 VanDerWaalsContact C-N 3.32Å
524	L	61	Low	65.1	Low	42 Å²	42	60.7 Å²	60.7	22%	0.22	33%	0.333	C	S	.	.	G	3₁₀ helix	trans	-87.9	0.1	-179.4	-58.2	179.4	0	0	0	112.5	W513 C516 L517 A521 T522 H526	W513-L524 HydrophobicContact CD2-CB 4.49Å; W513-L524 HydrophobicContact CE3-CB 4.41Å; W513-L524 HydrophobicContact CE3-CD1 3.98Å; W513-L524 HydrophobicContact CH2-CB 3.51Å; W513-L524 HydrophobicContact CH2-CD1 4.24Å; W513-L524 HydrophobicContact CH2-CD2 3.49Å; W513-L524 VanDerWaalsContact CH2-CD2 3.49Å; W513-L524 HydrophobicContact CH2-CG 3.89Å; W513-L524 HydrophobicContact CZ2-CB 3.58Å; W513-L524 HydrophobicContact CZ2-CD2 4.43Å; W513-L524 HydrophobicContact CZ2-CG 4.44Å; W513-L524 WeakPolarHBondContact CZ2-O 3.25Å; W513-L524 HydrophobicContact CZ3-CB 3.95Å; W513-L524 HydrophobicContact CZ3-CD1 3.79Å; W513-L524 HydrophobicContact CZ3-CD2 3.53Å; W513-L524 HydrophobicContact CZ3-CG 3.93Å; C516-L524 HydrophobicContact CB-CD1 4.23Å; L517-L524 HydrophobicContact CD2-CB 3.79Å; A521-L524 HydrophobicContact CB-CD1 4Å; A521-L524 HydrophobicContact CB-CG 4.33Å; A521-L524 PolarHBondContact O-N 2.88Å; T522-L524 PolarHBondContact O-N 3.43Å; L524-H526 PolarHBondContact O-N 2.82Å
525	A	56.3	Low	63.9	Low	37 Å²	37	61.3 Å²	61.3	31%	0.306	34%	0.34	S	S	.	.			trans	-74.3	120.7	-174.7	0	0	0	0	0	111.6	L517 T522 F523 L533	L517-A525 HydrophobicContact CD2-CB 4.17Å; T522-A525 VanDerWaalsContact O-CB 3.31Å; T522-A525 WeakPolarHBondContact O-CB 3.28Å; T522-A525 PolarHBondContact O-N 3.41Å; T522-A525 VanDerWaalsContact O-N 3.15Å; F523-A525 VanDerWaalsContact C-N 3.32Å; A525-L533 HydrophobicContact CB-CD1 4.44Å
526	H	56.6	Low	62.8	Low	138 Å²	138	64 Å²	64	64%	0.639	35%	0.354	S	S	*	.			trans	-103.1	150.8	168.1	-154	68.3	0	0	0	110.4	L524 S528 H529	L524-H526 PolarHBondContact O-N 2.82Å; H526-S528 PolarHBondContact O-N 3.12Å; H526-H529 PolarHBondContact O-N 3.05Å
527	S	55.6	Low	61.1	Low	96 Å²	96	69.7 Å²	69.7	67%	0.671	38%	0.381	S	S	*	.	G	3₁₀ helix	trans	-48.8	-31.7	-170.3	179.2	0	0	0	0	115	H529 H530	S527-H529 VanDerWaalsContact C-N 3.32Å; S527-H529 PolarHBondContact O-N 3.15Å; S527-H530 PolarHBondContact O-CD2 3.01Å; S527-H530 VanDerWaalsContact O-CD2 3.31Å
528	S	53.5	Low	59.4	Low	77 Å²	77	77 Å²	77	54%	0.538	42%	0.415	S	S	.	.	G	3₁₀ helix	trans	-76.9	-6.6	-179.5	74.4	0	0	0	0	115.6	H526 H531	H526-S528 PolarHBondContact O-N 3.12Å; S528-H531 PolarHBondContact O-CE1 3.23Å
529	H	56.9	Low	57.9	Low	34 Å²	34	85 Å²	85	16%	0.157	45%	0.451	C	S	.	.	G	3₁₀ helix	trans	-119	18.8	-173.5	-72.6	-55.2	0	0	0	114.8	H526 S527 H531 F532	H526-H529 PolarHBondContact O-N 3.05Å; S527-H529 VanDerWaalsContact C-N 3.32Å; S527-H529 PolarHBondContact O-N 3.15Å; H529-H531 AromaticContact ND1-CE1 3.6Å; H529-H531 AromaticContact ND1-NE2 3.37Å; H529-H531 PolarHBondContact ND1-NE2 3.13Å; H529-H531 PolarHBondContact O-N 3.06Å; H529-H531 VanDerWaalsContact O-N 3.13Å; H529-F532 HydrophobicContact CB-CD2 4.43Å; H529-F532 PolarHBondContact O-N 2.94Å; H529-F532 VanDerWaalsContact O-N 3.11Å
530	H	57.9	Low	56.3	Low	88 Å²	88	89.5 Å²	89.5	41%	0.407	48%	0.476	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.4	-22.3	175.1	-81.5	-59.3	0	0	0	114.1	S527 F532 L533 Y534	S527-H530 PolarHBondContact O-CD2 3.01Å; S527-H530 VanDerWaalsContact O-CD2 3.31Å; H530-F532 VanDerWaalsContact C-N 3.25Å; H530-F532 PolarHBondContact O-N 3.1Å; H530-L533 PolarHBondContact O-N 2.9Å; H530-Y534 HydrophobicContact CB-CD2 4.18Å; H530-Y534 AromaticContact ND1-CE2 3.71Å; H530-Y534 PolarHBondContact O-N 3.23Å
531	H	61.2	Low	55	Low	56 Å²	56	93.7 Å²	93.7	26%	0.259	48%	0.483	S	S	.	.	H	α-helix	trans	-63.2	-27.1	175	50.7	-107.4	0	0	0	113.6	S528 H529 L533 G535	S528-H531 PolarHBondContact O-CE1 3.23Å; H529-H531 AromaticContact ND1-CE1 3.6Å; H529-H531 AromaticContact ND1-NE2 3.37Å; H529-H531 PolarHBondContact ND1-NE2 3.13Å; H529-H531 PolarHBondContact O-N 3.06Å; H529-H531 VanDerWaalsContact O-N 3.13Å; H531-L533 VanDerWaalsContact C-N 3.29Å; H531-L533 PolarHBondContact O-N 3.48Å; H531-G535 WeakPolarHBondContact CA-O 3.22Å; H531-G535 CarbonylContact O-C 3.53Å; H531-G535 VanDerWaalsContact O-CA 3.28Å; H531-G535 WeakPolarHBondContact O-CA 3.44Å; H531-G535 PolarHBondContact O-N 2.87Å
532	F	58.3	Low	53.5	Low	6 Å²	6	99.3 Å²	99.3	3%	0.026	50%	0.5	C	S	.	.	H	α-helix	trans	-73.4	-21	173.1	-79.6	-81.8	0	0	0	112.7	Y125 Y126 T445 F446 M449 T514 H529 H530	Y125-F532 HydrophobicContact CD1-CD1 4.34Å; Y125-F532 HydrophobicContact CD1-CE1 4.28Å; Y126-F532 AromaticContact CD1-CZ 3.96Å; Y126-F532 HydrophobicContact CD1-CZ 3.96Å; Y126-F532 HydrophobicContact CE1-CE1 4.42Å; Y126-F532 AromaticContact CE1-CZ 3.83Å; Y126-F532 HydrophobicContact CE1-CZ 3.83Å; T445-F532 HydrophobicContact CG2-CE1 4.38Å; F446-F532 AromaticContact CE1-CE1 3.86Å; F446-F532 HydrophobicContact CE1-CE1 3.86Å; F446-F532 HydrophobicContact CZ-CE1 4.38Å; M449-F532 HydrophobicContact CE-CB 4.33Å; M449-F532 HydrophobicContact CE-CD1 3.77Å; M449-F532 HydrophobicContact CE-CG 4.43Å; M449-F532 WeakPolarHBondContact CE-O 3.33Å; M449-F532 HydrophobicContact SD-CD1 3.65Å; M449-F532 HydrophobicContact SD-CE1 4.24Å; T514-F532 HydrophobicContact CG2-CE2 4.38Å; T514-F532 HydrophobicContact CG2-CZ 4.33Å; H529-F532 HydrophobicContact CB-CD2 4.43Å; H529-F532 PolarHBondContact O-N 2.94Å; H529-F532 VanDerWaalsContact O-N 3.11Å; H530-F532 VanDerWaalsContact C-N 3.25Å; H530-F532 PolarHBondContact O-N 3.1Å
533	L	57.5	Low	52.3	Low	58 Å²	58	97.7 Å²	97.7	30%	0.304	50%	0.501	S	S	.	.	H	α-helix	trans	-93.3	-42.7	175.4	-96.1	94	0	0	0	112.7	T522 A525 H530 H531	T522-L533 HydrophobicContact CG2-CD2 4.04Å; A525-L533 HydrophobicContact CB-CD1 4.44Å; H530-L533 PolarHBondContact O-N 2.9Å; H531-L533 VanDerWaalsContact C-N 3.29Å; H531-L533 PolarHBondContact O-N 3.48Å
534	Y	54.4	Low	51.5	Low	181 Å²	181	93.4 Å²	93.4	71%	0.71	48%	0.484	S	S	*	.	H	α-helix	trans	-107.8	-2.5	-168.3	-66.1	-74.9	0	0	0	114.2	H530	H530-Y534 HydrophobicContact CB-CD2 4.18Å; H530-Y534 AromaticContact ND1-CE2 3.71Å; H530-Y534 PolarHBondContact O-N 3.23Å
535	G	59.2	Low	50.3	Low	14 Å²	14	97.1 Å²	97.1	14%	0.144	51%	0.509	C	S	.	.			trans	82.3	179	-173.2	0	0	0	0	0	112.6	H531	H531-G535 WeakPolarHBondContact CA-O 3.22Å; H531-G535 CarbonylContact O-C 3.53Å; H531-G535 VanDerWaalsContact O-CA 3.28Å; H531-G535 WeakPolarHBondContact O-CA 3.44Å; H531-G535 PolarHBondContact O-N 2.87Å
536	L	59.6	Low	49.3	Very low	57 Å²	57	99.9 Å²	99.9	30%	0.298	53%	0.525	S	S	.	.			trans	-76.2	136.3	176.7	-62.9	167.4	0	0	0	110	L124 Y125	L124-L536 HydrophobicContact CB-CD1 4.01Å; Y125-L536 HydrophobicContact CE1-CG 4.3Å; Y125-L536 HydrophobicContact CE2-CD1 4.29Å
537	L	47.3	Very low	48.2	Very low	153 Å²	153	100.6 Å²	100.6	80%	0.801	57%	0.571	S	S	*	*			trans	-68	141.6	171.5	-83.4	157.3	0	0	0	110	E539 D540	L537-E539 PolarHBondContact O-N 3.2Å; L537-D540 PolarHBondContact O-N 3.19Å
538	E	45.2	Very low	47.8	Very low	161 Å²	161	100.9 Å²	100.9	75%	0.752	57%	0.566	S	S	*	*	G	3₁₀ helix	trans	-54.1	-20.2	-175	-78.8	-176.7	145.8	0	0	115	D540 Q541	E538-D540 VanDerWaalsContact C-N 3.35Å; E538-D540 PolarHBondContact O-N 3.42Å; E538-Q541 PolarHBondContact O-N 3.03Å
539	E	42	Very low	47.5	Very low	178 Å²	178	102.1 Å²	102.1	83%	0.832	57%	0.567	S	S	*	*	G	3₁₀ helix	trans	-66	-31.5	179.2	-75.6	-167.5	145.2	0	0	113.6	L537	L537-E539 PolarHBondContact O-N 3.2Å
540	D	42.8	Very low	47	Very low	132 Å²	132	105.9 Å²	105.9	71%	0.706	59%	0.59	S	S	*	*	G	3₁₀ helix	trans	-79.1	-17.1	178.7	-97.1	-25.6	0	0	0	113.3	L537 E538	L537-D540 PolarHBondContact O-N 3.19Å; E538-D540 VanDerWaalsContact C-N 3.35Å; E538-D540 PolarHBondContact O-N 3.42Å
541	Q	40.5	Very low	46.3	Very low	136 Å²	136	106.9 Å²	106.9	64%	0.636	60%	0.6	S	S	*	*	G	3₁₀ helix	trans	-75.7	-24.3	174.9	-85.1	-173.3	-18.4	0	0	113.2	E538 G543	E538-Q541 PolarHBondContact O-N 3.03Å; Q541-G543 VanDerWaalsContact C-N 3.32Å
542	K	37.2	Very low	45.4	Very low	156 Å²	156	110.1 Å²	110.1	68%	0.678	62%	0.622	S	S	*	*	G	3₁₀ helix	trans	-78.1	-14.4	179.4	-82.4	178.2	177.8	170.6	0	114.1	E544 T545 S546	K542-E544 VanDerWaalsContact C-N 3.29Å; K542-E544 PolarHBondContact O-N 3.3Å; K542-T545 PolarHBondContact O-OG1 3.13Å; K542-S546 PolarHBondContact O-OG 3.27Å
543	G	36.7	Very low	44.6	Very low	57 Å²	57	117.1 Å²	117.1	59%	0.588	66%	0.661	S	S	*	*	G	3₁₀ helix	trans	-70.9	-18.1	178	0	0	0	0	0	114.7	Q541	Q541-G543 VanDerWaalsContact C-N 3.32Å
544	E	42.1	Very low	43.6	Very low	104 Å²	104	121.3 Å²	121.3	49%	0.486	69%	0.687	S	S	.	*	G	3₁₀ helix	trans	-90.8	-15.4	179.5	-79.7	178.5	-179.6	0	0	114.3	R389 K542	R389-E544 IonicContact CZ-OE1 2.76Å; R389-E544 IonicContact NH1-OE1 2.72Å; R389-E544 PolarHBondContact NH1-OE1 3.19Å; R389-E544 IonicContact NH2-OE1 3.33Å; R389-E544 PolarHBondContact NH2-OE1 3.3Å; K542-E544 VanDerWaalsContact C-N 3.29Å; K542-E544 PolarHBondContact O-N 3.3Å
545	T	36.1	Very low	42.8	Very low	121 Å²	121	116.7 Å²	116.7	74%	0.742	69%	0.685	S	S	*	*	S	Bend	trans	-95.7	2.9	177.1	41.5	0	0	0	0	113.8	K542	K542-T545 PolarHBondContact O-OG1 3.13Å
546	S	34.1	Very low	41.4	Very low	94 Å²	94	125.3 Å²	125.3	66%	0.657	73%	0.73	S	S	*	*			trans	-135.2	82.2	-176.3	-30.8	0	0	0	0	109.4	K542	K542-S546 PolarHBondContact O-OG 3.27Å
547	G	33.8	Very low	39.8	Very low	154 Å²	154	131.5 Å²	131.5	100%	1.588	77%	0.77	S	S	*	*			trans	-171.9	0	177.5	0	0	0	0	0	111.9

Retrieved 547 of 547 residues in 2682.6 ms (Link to these results)

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