A0A096N6N1_PAPAN Loading...

Solute carrier family 18 member 3

Electrogenic antiporter that exchanges one cholinergic neurotransmitter, acetylcholine or choline, with two intravesicular protons across the membrane of synaptic vesicles. Uses the electrochemical proton gradient established by the V-type proton-pump ATPase to store neurotransmitters inside the vesicles prior to their release via exocytosis. Determines cholinergic vesicular quantal size at presynaptic nerve terminals in developing neuro-muscular junctions with an impact on motor neuron differentiation and innervation pattern. Part of forebrain cholinergic system, regulates hippocampal synapse transmissions that underlie spatial memory formation. Can transport serotonin.

AlphaFold DB , UniProt , Accession A0A096N6N1, Species PAPAN (Papio anubis, Olive baboon), Gene SLC18A3, Length 532 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	40.8	Very low	51.2	Low	248 Å²	248	129 Å²	129	100%	1.222	73%	0.73	S	S	*	*				0	91	0	-94.4	175.5	172.4	0	0	106.9
2	E	39.3	Very low	52.1	Low	184 Å²	184	121.9 Å²	121.9	86%	0.86	70%	0.7	S	S	*	*			trans	-86.4	132.9	173	-101.6	179.2	117.7	0	0	109.2
3	P	46.2	Very low	52.6	Low	127 Å²	127	117.1 Å²	117.1	83%	0.825	68%	0.683	S	S	*	*			trans	-102.9	92.3	168.6	34.5	-22.4	0	0	0	109.1
4	A	48.9	Very low	52.8	Low	83 Å²	83	112.9 Å²	112.9	69%	0.686	67%	0.669	S	S	*	*			trans	-130.3	57.8	177.2	0	0	0	0	0	111.2
5	E	54.5	Low	53.7	Low	148 Å²	148	110.7 Å²	110.7	69%	0.692	66%	0.657	S	S	*	*			trans	-136.8	8.4	-177.9	-102.3	-167.9	163.4	0	0	120.1
6	P	53.2	Low	54.2	Low	107 Å²	107	113.3 Å²	113.3	70%	0.695	66%	0.657	S	S	*	*	H	α-helix	trans	-85	-27.6	175.8	29.5	-30.6	0	0	0	114.3	A10	P6-A10 PolarHBondContact O-N 3.39Å
7	A	54.2	Low	54.5	Low	77 Å²	77	113.6 Å²	113.6	64%	0.636	66%	0.656	S	S	*	*	H	α-helix	trans	-78.2	-31.4	-173.5	0	0	0	0	0	113.9	R11	A7-R11 PolarHBondContact O-N 3.45Å
8	G	54.6	Low	54.9	Low	52 Å²	52	111.9 Å²	111.9	54%	0.536	65%	0.651	S	S	.	*	H	α-helix	trans	-71.5	-40.1	178.5	0	0	0	0	0	112.8	R11 A12	G8-R11 PolarHBondContact O-N 3.43Å; G8-A12 VanDerWaalsContact O-CB 3.29Å; G8-A12 WeakPolarHBondContact O-CB 3.34Å; G8-A12 PolarHBondContact O-N 2.82Å
9	Q	56	Low	55.3	Low	130 Å²	130	113.2 Å²	113.2	61%	0.607	65%	0.65	S	S	*	*	H	α-helix	trans	-69.4	-37.3	177.9	-69.1	-177.6	-6.1	0	0	112.3	A12 A13	Q9-A12 PolarHBondContact O-N 3.47Å; Q9-A13 VanDerWaalsContact O-CB 3.26Å; Q9-A13 WeakPolarHBondContact O-CB 3.29Å; Q9-A13 PolarHBondContact O-N 2.67Å
10	A	55.3	Low	55.5	Low	63 Å²	63	110.5 Å²	110.5	52%	0.521	64%	0.642	S	S	.	*	H	α-helix	trans	-65.6	-41.4	174.5	0	0	0	0	0	112.3	P6 A13 A14	P6-A10 PolarHBondContact O-N 3.39Å; A10-A13 PolarHBondContact O-N 3.22Å; A10-A14 VanDerWaalsContact O-CB 3.29Å; A10-A14 WeakPolarHBondContact O-CB 3.24Å; A10-A14 PolarHBondContact O-N 2.92Å
11	R	60.3	Low	55.7	Low	200 Å²	200	108.9 Å²	108.9	76%	0.755	63%	0.634	S	S	*	*	H	α-helix	trans	-66.1	-39.7	173.4	-101.3	-179.4	171.7	175.9	-1.7	112.6	A7 G8 A14 T15	A7-R11 PolarHBondContact O-N 3.45Å; G8-R11 PolarHBondContact O-N 3.43Å; R11-A14 PolarHBondContact O-N 2.92Å; R11-T15 WeakPolarHBondContact O-CB 3.26Å; R11-T15 PolarHBondContact O-N 3.08Å; R11-T15 PolarHBondContact O-OG1 3.24Å
12	A	62.4	Low	56.7	Low	44 Å²	44	98.4 Å²	98.4	36%	0.364	59%	0.59	S	S	.	*	H	α-helix	trans	-67.8	-37.4	176.3	0	0	0	0	0	112.3	G8 Q9 T15 K16	G8-A12 VanDerWaalsContact O-CB 3.29Å; G8-A12 WeakPolarHBondContact O-CB 3.34Å; G8-A12 PolarHBondContact O-N 2.82Å; Q9-A12 PolarHBondContact O-N 3.47Å; A12-T15 VanDerWaalsContact CA-OG1 3.24Å; A12-T15 WeakPolarHBondContact CA-OG1 3.33Å; A12-T15 PolarHBondContact O-OG1 3.44Å; A12-T15 VanDerWaalsContact O-OG1 3.08Å; A12-K16 WeakPolarHBondContact O-CB 3.42Å; A12-K16 WeakPolarHBondContact O-CG 3.29Å; A12-K16 PolarHBondContact O-N 2.9Å
13	A	58	Low	57.7	Low	59 Å²	59	92.5 Å²	92.5	49%	0.488	57%	0.572	S	S	.	*	H	α-helix	trans	-68.9	-41.5	173.3	0	0	0	0	0	111.5	Q9 A10 K16 L17	Q9-A13 VanDerWaalsContact O-CB 3.26Å; Q9-A13 WeakPolarHBondContact O-CB 3.29Å; Q9-A13 PolarHBondContact O-N 2.67Å; A10-A13 PolarHBondContact O-N 3.22Å; A13-K16 PolarHBondContact O-N 2.78Å; A13-L17 VanDerWaalsContact O-CB 3.26Å; A13-L17 WeakPolarHBondContact O-CB 3.26Å; A13-L17 PolarHBondContact O-N 3.42Å
14	A	55.9	Low	58.1	Low	58 Å²	58	87.5 Å²	87.5	48%	0.479	54%	0.541	S	S	.	.	H	α-helix	trans	-65.5	-38.2	175.9	0	0	0	0	0	112.4	A10 R11 S18	A10-A14 VanDerWaalsContact O-CB 3.29Å; A10-A14 WeakPolarHBondContact O-CB 3.24Å; A10-A14 PolarHBondContact O-N 2.92Å; R11-A14 PolarHBondContact O-N 2.92Å; A14-S18 WeakPolarHBondContact O-CB 3.42Å; A14-S18 PolarHBondContact O-N 3.46Å
15	T	66.3	Low	58.6	Low	80 Å²	80	85.2 Å²	85.2	49%	0.491	52%	0.518	S	S	.	.	H	α-helix	trans	-70.7	-41.9	174.4	35.4	0	0	0	0	111.9	R11 A12 L17 S18 E19	R11-T15 WeakPolarHBondContact O-CB 3.26Å; R11-T15 PolarHBondContact O-N 3.08Å; R11-T15 PolarHBondContact O-OG1 3.24Å; A12-T15 VanDerWaalsContact CA-OG1 3.24Å; A12-T15 WeakPolarHBondContact CA-OG1 3.33Å; A12-T15 PolarHBondContact O-OG1 3.44Å; A12-T15 VanDerWaalsContact O-OG1 3.08Å; T15-L17 VanDerWaalsContact C-N 3.34Å; T15-L17 PolarHBondContact O-N 2.82Å; T15-S18 CarbonylContact O-C 3.56Å; T15-S18 WeakPolarHBondContact O-CB 3.5Å; T15-S18 PolarHBondContact O-N 3.25Å; T15-E19 WeakPolarHBondContact O-CB 3.41Å; T15-E19 WeakPolarHBondContact O-CG 3.41Å; T15-E19 PolarHBondContact O-N 2.89Å
16	K	61.6	Low	59.1	Low	152 Å²	152	88.1 Å²	88.1	66%	0.661	52%	0.522	S	S	*	.	H	α-helix	trans	-63.3	-38	172.4	-78.3	-178.9	178.3	-178.6	0	112.8	A12 A13 E19 A20	A12-K16 WeakPolarHBondContact O-CB 3.42Å; A12-K16 WeakPolarHBondContact O-CG 3.29Å; A12-K16 PolarHBondContact O-N 2.9Å; A13-K16 PolarHBondContact O-N 2.78Å; K16-E19 PolarHBondContact O-N 2.81Å; K16-A20 WeakPolarHBondContact O-CB 3.2Å; K16-A20 PolarHBondContact O-N 3.46Å
17	L	58.6	Low	60.1	Low	120 Å²	120	88.1 Å²	88.1	63%	0.628	51%	0.513	S	S	*	.	H	α-helix	trans	-66.5	-43.3	173.5	-165.1	79.1	0	0	0	110.2	A13 T15 E19 A20 V21	A13-L17 VanDerWaalsContact O-CB 3.26Å; A13-L17 WeakPolarHBondContact O-CB 3.26Å; A13-L17 PolarHBondContact O-N 3.42Å; T15-L17 VanDerWaalsContact C-N 3.34Å; T15-L17 PolarHBondContact O-N 2.82Å; L17-E19 VanDerWaalsContact C-N 3.34Å; L17-E19 PolarHBondContact O-N 2.84Å; L17-A20 PolarHBondContact O-N 2.8Å; L17-V21 HydrophobicContact CG-CG2 4.39Å; L17-V21 WeakPolarHBondContact O-CB 3.16Å; L17-V21 WeakPolarHBondContact O-CG2 3.21Å; L17-V21 PolarHBondContact O-N 2.88Å
18	S	62.8	Low	61	Low	82 Å²	82	88.6 Å²	88.6	57%	0.573	51%	0.509	S	S	*	.	H	α-helix	trans	-61.5	-39.1	174.6	175.7	0	0	0	0	112.6	A14 T15 G22	A14-S18 WeakPolarHBondContact O-CB 3.42Å; A14-S18 PolarHBondContact O-N 3.46Å; T15-S18 CarbonylContact O-C 3.56Å; T15-S18 WeakPolarHBondContact O-CB 3.5Å; T15-S18 PolarHBondContact O-N 3.25Å; S18-G22 WeakPolarHBondContact O-CA 3.27Å; S18-G22 PolarHBondContact O-N 3.4Å
19	E	62.6	Low	62.1	Low	137 Å²	137	95.9 Å²	95.9	64%	0.64	52%	0.521	S	S	*	.	H	α-helix	trans	-75.1	-39.5	177.3	-77	-177.9	166.4	0	0	111.8	T15 K16 L17 G22 A23	T15-E19 WeakPolarHBondContact O-CB 3.41Å; T15-E19 WeakPolarHBondContact O-CG 3.41Å; T15-E19 PolarHBondContact O-N 2.89Å; K16-E19 PolarHBondContact O-N 2.81Å; L17-E19 VanDerWaalsContact C-N 3.34Å; L17-E19 PolarHBondContact O-N 2.84Å; E19-G22 CarbonylContact O-C 3.56Å; E19-G22 PolarHBondContact O-N 2.73Å; E19-A23 WeakPolarHBondContact O-CB 3.17Å; E19-A23 PolarHBondContact O-N 3.32Å
20	A	58.7	Low	63.2	Low	59 Å²	59	96 Å²	96	49%	0.488	52%	0.516	S	S	.	.	H	α-helix	trans	-66.9	-41.7	174.9	0	0	0	0	0	111.6	K16 L17 A24	K16-A20 WeakPolarHBondContact O-CB 3.2Å; K16-A20 PolarHBondContact O-N 3.46Å; L17-A20 PolarHBondContact O-N 2.8Å; A20-A24 WeakPolarHBondContact O-CB 3.1Å; A20-A24 PolarHBondContact O-N 2.78Å
21	V	59.4	Low	64.4	Low	76 Å²	76	95.8 Å²	95.8	46%	0.461	50%	0.504	S	S	.	.	H	α-helix	trans	-64.7	-44.8	171.4	170.8	0	0	0	0	109.5	L17 A23 A24 L25	L17-V21 HydrophobicContact CG-CG2 4.39Å; L17-V21 WeakPolarHBondContact O-CB 3.16Å; L17-V21 WeakPolarHBondContact O-CG2 3.21Å; L17-V21 PolarHBondContact O-N 2.88Å; V21-A23 PolarHBondContact O-N 3.36Å; V21-A24 PolarHBondContact O-N 3.45Å; V21-L25 HydrophobicContact CG1-CD1 3.68Å; V21-L25 HydrophobicContact CG1-CG 4.32Å; V21-L25 VanDerWaalsContact O-CB 3.27Å; V21-L25 WeakPolarHBondContact O-CB 3.17Å; V21-L25 WeakPolarHBondContact O-CD1 3.1Å; V21-L25 WeakPolarHBondContact O-CG 3.37Å; V21-L25 PolarHBondContact O-N 2.85Å
22	G	63	Low	65.5	Low	29 Å²	29	91 Å²	91	30%	0.299	49%	0.486	S	S	.	.	H	α-helix	trans	-63.1	-35.6	177	0	0	0	0	0	114.2	S18 E19 R26	S18-G22 WeakPolarHBondContact O-CA 3.27Å; S18-G22 PolarHBondContact O-N 3.4Å; E19-G22 CarbonylContact O-C 3.56Å; E19-G22 PolarHBondContact O-N 2.73Å; G22-R26 WeakPolarHBondContact O-CG 3.36Å; G22-R26 PolarHBondContact O-N 3.46Å
23	A	58.7	Low	66.6	Low	59 Å²	59	97.4 Å²	97.4	49%	0.488	50%	0.501	S	S	.	.	H	α-helix	trans	-76	-41.9	175.5	0	0	0	0	0	111.4	E19 V21 L25 R26	E19-A23 WeakPolarHBondContact O-CB 3.17Å; E19-A23 PolarHBondContact O-N 3.32Å; V21-A23 PolarHBondContact O-N 3.36Å; A23-L25 PolarHBondContact O-N 3.1Å; A23-R26 PolarHBondContact O-N 3.42Å; A23-R26 VanDerWaalsContact O-N 3.1Å
24	A	55.2	Low	68	Low	22 Å²	22	97 Å²	97	18%	0.182	49%	0.49	C	S	.	.	H	α-helix	trans	-62.2	-32.4	172.8	0	0	0	0	0	112.5	A20 V21 R26 R30	A20-A24 WeakPolarHBondContact O-CB 3.1Å; A20-A24 PolarHBondContact O-N 2.78Å; V21-A24 PolarHBondContact O-N 3.45Å; A24-R26 VanDerWaalsContact C-N 3.3Å; A24-R26 PolarHBondContact O-N 3.19Å; A24-R30 WeakPolarHBondContact O-CD 3.28Å
25	L	60.2	Low	69.5	Low	36 Å²	36	94.5 Å²	94.5	19%	0.188	47%	0.468	C	S	.	.	T	Hydrogen-bonded Turn	trans	-72.2	-19.5	175.3	-77.1	165.5	0	0	0	113.6	V21 A23 L34 V262	V21-L25 HydrophobicContact CG1-CD1 3.68Å; V21-L25 HydrophobicContact CG1-CG 4.32Å; V21-L25 VanDerWaalsContact O-CB 3.27Å; V21-L25 WeakPolarHBondContact O-CB 3.17Å; V21-L25 WeakPolarHBondContact O-CD1 3.1Å; V21-L25 WeakPolarHBondContact O-CG 3.37Å; V21-L25 PolarHBondContact O-N 2.85Å; A23-L25 PolarHBondContact O-N 3.1Å; L25-L34 HydrophobicContact CD2-CD1 3.7Å; L25-V262 HydrophobicContact CD2-CB 4.3Å; L25-V262 HydrophobicContact CD2-CG1 4.49Å; L25-V262 HydrophobicContact CD2-CG2 3.53Å
26	R	63.4	Low	70.6	Confident	208 Å²	208	92 Å²	92	79%	0.785	45%	0.452	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.9	-15	-179.5	-77.2	175.6	-174.8	-161	3.1	113.9	G22 A23 A24 P28	G22-R26 WeakPolarHBondContact O-CG 3.36Å; G22-R26 PolarHBondContact O-N 3.46Å; A23-R26 PolarHBondContact O-N 3.42Å; A23-R26 VanDerWaalsContact O-N 3.1Å; A24-R26 VanDerWaalsContact C-N 3.3Å; A24-R26 PolarHBondContact O-N 3.19Å; R26-P28 WeakPolarHBondContact O-CD 3.39Å
27	E	76	Confident	72.1	Confident	108 Å²	108	88.5 Å²	88.5	51%	0.505	44%	0.443	S	S	.	.			trans	-69.2	118.6	175	-79.1	178.3	177	0	0	110.3	R29 R30 Q31	E27-R29 VanDerWaalsContact C-N 3.25Å; E27-R29 PolarHBondContact O-N 3.5Å; E27-R29 VanDerWaalsContact O-N 3.17Å; E27-R30 HydrophobicContact CB-CB 3.9Å; E27-R30 PolarHBondContact O-N 3.36Å; E27-Q31 WeakPolarHBondContact O-CB 3.49Å; E27-Q31 PolarHBondContact O-N 2.9Å
28	P	72.8	Confident	73.6	Confident	86 Å²	86	82.8 Å²	82.8	56%	0.558	41%	0.413	S	S	*	.	H	α-helix	trans	-61.8	-32.7	-172.2	21.2	-31.7	0	0	0	112.7	R26 R32	R26-P28 WeakPolarHBondContact O-CD 3.39Å; P28-R32 WeakPolarHBondContact O-CG 3.4Å; P28-R32 PolarHBondContact O-N 2.87Å; P28-R32 VanDerWaalsContact O-N 3.16Å
29	R	76.3	Confident	75	Confident	206 Å²	206	78.9 Å²	78.9	78%	0.777	39%	0.386	S	S	*	.	H	α-helix	trans	-68.8	-40.7	175.4	-70.5	-177.9	175.2	168.2	-1.7	112.4	E27 R33	E27-R29 VanDerWaalsContact C-N 3.25Å; E27-R29 PolarHBondContact O-N 3.5Å; E27-R29 VanDerWaalsContact O-N 3.17Å; R29-R33 WeakPolarHBondContact O-CG 3.48Å; R29-R33 PolarHBondContact O-N 3.02Å
30	R	79.4	Confident	76.5	Confident	132 Å²	132	72.5 Å²	72.5	50%	0.498	36%	0.357	S	S	.	.	H	α-helix	trans	-74.1	-36.8	-178.6	-154.7	169.9	-177	178.2	-1.4	110.9	A24 E27 R33 L34	A24-R30 WeakPolarHBondContact O-CD 3.28Å; E27-R30 HydrophobicContact CB-CB 3.9Å; E27-R30 PolarHBondContact O-N 3.36Å; R30-R33 PolarHBondContact O-N 3.17Å; R30-L34 WeakPolarHBondContact O-CG 3.18Å; R30-L34 PolarHBondContact O-N 3.48Å
31	Q	81.3	Confident	78.1	Confident	59 Å²	59	71.1 Å²	71.1	28%	0.276	34%	0.342	S	S	.	.	H	α-helix	trans	-60.6	-46.7	172.6	-162.8	-175.3	14.3	0	0	112	E27 R33 L34 L35 V262	E27-Q31 WeakPolarHBondContact O-CB 3.49Å; E27-Q31 PolarHBondContact O-N 2.9Å; Q31-R33 VanDerWaalsContact C-N 3.33Å; Q31-R33 PolarHBondContact O-N 3.38Å; Q31-L34 PolarHBondContact O-N 3Å; Q31-L35 WeakPolarHBondContact O-CG 3.33Å; Q31-L35 PolarHBondContact O-N 3.02Å; Q31-V262 HydrophobicContact CG-CG1 3.74Å; Q31-V262 PolarHBondContact NE2-O 3.04Å
32	R	83	Confident	79.7	Confident	100 Å²	100	67.6 Å²	67.6	38%	0.377	32%	0.32	S	S	.	.	H	α-helix	trans	-60.1	-39.9	176.3	-73.5	179.4	-171.2	-173	0.1	112.9	P28 L36 K203 Y204	P28-R32 WeakPolarHBondContact O-CG 3.4Å; P28-R32 PolarHBondContact O-N 2.87Å; P28-R32 VanDerWaalsContact O-N 3.16Å; R32-L36 PolarHBondContact O-N 3.34Å; R32-K203 WeakPolarHBondContact CD-O 3.49Å; R32-K203 HydrophobicContact CG-CB 4.49Å; R32-K203 PolarHBondContact NE-O 3.15Å; R32-Y204 PolarHBondContact O-OH 2.78Å
33	R	85.8	Confident	81	Confident	178 Å²	178	66.2 Å²	66.2	67%	0.672	31%	0.306	S	S	*	.	H	α-helix	trans	-68.1	-40.3	176.4	-71.5	179.6	-177.5	177.4	0.8	112.2	R29 R30 Q31 L36 V37	R29-R33 WeakPolarHBondContact O-CG 3.48Å; R29-R33 PolarHBondContact O-N 3.02Å; R30-R33 PolarHBondContact O-N 3.17Å; Q31-R33 VanDerWaalsContact C-N 3.33Å; Q31-R33 PolarHBondContact O-N 3.38Å; R33-L36 WeakPolarHBondContact O-CB 3.41Å; R33-L36 PolarHBondContact O-N 3.42Å; R33-V37 WeakPolarHBondContact O-CG2 3.49Å; R33-V37 PolarHBondContact O-N 3.49Å
34	L	87	Confident	82.6	Confident	50 Å²	50	64.7 Å²	64.7	26%	0.262	29%	0.29	S	S	.	.	H	α-helix	trans	-64.1	-42.7	175.4	-76.9	164.9	0	0	0	111.7	L25 R30 Q31 L36 V37 I38 V262	L25-L34 HydrophobicContact CD2-CD1 3.7Å; R30-L34 WeakPolarHBondContact O-CG 3.18Å; R30-L34 PolarHBondContact O-N 3.48Å; Q31-L34 PolarHBondContact O-N 3Å; L34-L36 VanDerWaalsContact C-N 3.33Å; L34-L36 PolarHBondContact O-N 3.33Å; L34-V37 PolarHBondContact O-N 3.05Å; L34-I38 WeakPolarHBondContact O-CD1 3.33Å; L34-I38 VanDerWaalsContact O-CG1 3.32Å; L34-I38 WeakPolarHBondContact O-CG1 3.49Å; L34-I38 PolarHBondContact O-N 3.44Å; L34-V262 HydrophobicContact CB-CG1 4.23Å; L34-V262 HydrophobicContact CB-CG2 4.27Å; L34-V262 HydrophobicContact CD1-CG2 4.38Å
35	L	87.6	Confident	84.4	Confident	5 Å²	5	63.7 Å²	63.7	3%	0.026	28%	0.282	C	S	.	.	H	α-helix	trans	-62.2	-40	174.3	-69.7	174.8	0	0	0	112.1	Q31 V37 I38 V39 M199 K203 L259 V262 A263	Q31-L35 WeakPolarHBondContact O-CG 3.33Å; Q31-L35 PolarHBondContact O-N 3.02Å; L35-V37 VanDerWaalsContact C-N 3.34Å; L35-V37 PolarHBondContact O-N 3.24Å; L35-I38 HydrophobicContact CD2-CD1 4.11Å; L35-I38 PolarHBondContact O-N 3.12Å; L35-V39 WeakPolarHBondContact O-CG2 3.45Å; L35-V39 PolarHBondContact O-N 2.95Å; L35-M199 HydrophobicContact CB-SD 4.35Å; L35-M199 HydrophobicContact CD1-SD 4.49Å; L35-M199 HydrophobicContact CD2-SD 3.97Å; L35-M199 HydrophobicContact CG-SD 4.5Å; L35-K203 HydrophobicContact CD1-CD 4.09Å; L35-K203 HydrophobicContact CD1-CG 4.2Å; L35-L259 HydrophobicContact CD2-CD1 4.26Å; L35-V262 HydrophobicContact CD2-CB 4.43Å; L35-V262 HydrophobicContact CD2-CG1 3.77Å; L35-V262 HydrophobicContact CG-CG1 3.93Å; L35-A263 HydrophobicContact CD2-CB 4.14Å
36	L	89.8	Confident	85.8	Confident	29 Å²	29	62.2 Å²	62.2	15%	0.152	27%	0.274	C	S	.	.	H	α-helix	trans	-59.9	-45.4	172.9	177.7	63.1	0	0	0	111.2	R32 R33 L34 V39 C40 I200 Y204 A213	R32-L36 PolarHBondContact O-N 3.34Å; R33-L36 WeakPolarHBondContact O-CB 3.41Å; R33-L36 PolarHBondContact O-N 3.42Å; L34-L36 VanDerWaalsContact C-N 3.33Å; L34-L36 PolarHBondContact O-N 3.33Å; L36-V39 PolarHBondContact O-N 3.28Å; L36-C40 WeakPolarHBondContact O-CB 3.38Å; L36-C40 PolarHBondContact O-N 3.38Å; L36-C40 PolarHBondContact O-SG 3.16Å; L36-I200 HydrophobicContact CD1-CD1 3.62Å; L36-I200 HydrophobicContact CD1-CG1 4.04Å; L36-Y204 HydrophobicContact CB-CE2 4.36Å; L36-A213 HydrophobicContact CD1-CB 4.05Å; L36-A213 HydrophobicContact CD2-CB 4.29Å
37	V	92.1	Very high	87	Confident	77 Å²	77	53.5 Å²	53.5	47%	0.467	24%	0.243	S	C	.	.	H	α-helix	trans	-61.4	-45.1	177.3	171.4	0	0	0	0	111.3	R33 L34 L35 V39 C40 V41	R33-V37 WeakPolarHBondContact O-CG2 3.49Å; R33-V37 PolarHBondContact O-N 3.49Å; L34-V37 PolarHBondContact O-N 3.05Å; L35-V37 VanDerWaalsContact C-N 3.34Å; L35-V37 PolarHBondContact O-N 3.24Å; V37-V39 PolarHBondContact O-N 2.93Å; V37-C40 PolarHBondContact O-N 3.24Å; V37-V41 HydrophobicContact CG1-CG2 4.31Å; V37-V41 VanDerWaalsContact O-CG2 3.32Å; V37-V41 WeakPolarHBondContact O-CG2 3.49Å; V37-V41 PolarHBondContact O-N 3.49Å
38	I	91.6	Very high	87.7	Confident	0 Å²	0	49.2 Å²	49.2	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-56.6	-51.1	176.7	-69.4	156.7	0	0	0	110.2	L34 L35 C40 V41 A42 L155 D255 L258 L259 V262	L34-I38 WeakPolarHBondContact O-CD1 3.33Å; L34-I38 VanDerWaalsContact O-CG1 3.32Å; L34-I38 WeakPolarHBondContact O-CG1 3.49Å; L34-I38 PolarHBondContact O-N 3.44Å; L35-I38 HydrophobicContact CD2-CD1 4.11Å; L35-I38 PolarHBondContact O-N 3.12Å; I38-C40 VanDerWaalsContact C-N 3.33Å; I38-C40 PolarHBondContact O-N 3.03Å; I38-V41 PolarHBondContact O-N 3.34Å; I38-V41 VanDerWaalsContact O-N 3.15Å; I38-A42 WeakPolarHBondContact O-CB 3.3Å; I38-A42 PolarHBondContact O-N 2.97Å; I38-L155 HydrophobicContact CG2-CD2 4.47Å; I38-D255 WeakPolarHBondContact CA-OD1 3.05Å; I38-L258 HydrophobicContact CD1-CD2 4.37Å; I38-L258 HydrophobicContact CD1-CG 4Å; I38-L258 HydrophobicContact CG1-CB 4.36Å; I38-L258 HydrophobicContact CG1-CD2 3.77Å; I38-L258 HydrophobicContact CG1-CG 3.89Å; I38-L259 HydrophobicContact CD1-CB 4.4Å; I38-L259 HydrophobicContact CD1-CD1 4.38Å; I38-L259 HydrophobicContact CG2-CB 4.05Å; I38-L259 HydrophobicContact CG2-CD1 4.13Å; I38-V262 HydrophobicContact CD1-CB 4.16Å; I38-V262 HydrophobicContact CD1-CG2 4.11Å
39	V	91.5	Very high	88.4	Confident	0 Å²	0	45.1 Å²	45.1	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-62	-42.1	179.4	174.4	0	0	0	0	111.3	L35 L36 V37 V41 A42 L43 L155 G196 M199 I200	L35-V39 WeakPolarHBondContact O-CG2 3.45Å; L35-V39 PolarHBondContact O-N 2.95Å; L36-V39 PolarHBondContact O-N 3.28Å; V37-V39 PolarHBondContact O-N 2.93Å; V39-V41 VanDerWaalsContact C-N 3.31Å; V39-V41 PolarHBondContact O-N 3.02Å; V39-A42 PolarHBondContact O-N 3.22Å; V39-L43 HydrophobicContact CG1-CD1 3.87Å; V39-L43 HydrophobicContact CG1-CG 4.22Å; V39-L43 WeakPolarHBondContact O-CB 3.04Å; V39-L43 VanDerWaalsContact O-CG 3.27Å; V39-L43 WeakPolarHBondContact O-CG 3.49Å; V39-L43 PolarHBondContact O-N 2.85Å; V39-L155 HydrophobicContact CG2-CD2 4.12Å; V39-G196 WeakPolarHBondContact CG1-O 3.48Å; V39-M199 HydrophobicContact CG2-SD 4.19Å; V39-I200 HydrophobicContact CB-CD1 3.94Å; V39-I200 HydrophobicContact CB-CG1 4.21Å; V39-I200 HydrophobicContact CG1-CD1 3.45Å; V39-I200 VanDerWaalsContact CG1-CD1 3.45Å; V39-I200 HydrophobicContact CG1-CG1 4.04Å; V39-I200 HydrophobicContact CG2-CG1 4.3Å
40	C	92.9	Very high	88.8	Confident	4 Å²	4	35.8 Å²	35.8	3%	0.027	16%	0.161	C	C	.	.	H	α-helix	trans	-60.3	-40	175.4	-71.9	0	0	0	0	112.4	L36 V37 I38 L44 F220	L36-C40 WeakPolarHBondContact O-CB 3.38Å; L36-C40 PolarHBondContact O-N 3.38Å; L36-C40 PolarHBondContact O-SG 3.16Å; V37-C40 PolarHBondContact O-N 3.24Å; I38-C40 VanDerWaalsContact C-N 3.33Å; I38-C40 PolarHBondContact O-N 3.03Å; C40-L44 WeakPolarHBondContact O-CB 3.32Å; C40-L44 PolarHBondContact O-N 3.37Å; C40-F220 HydrophobicContact CB-CB 4.29Å; C40-F220 HydrophobicContact CB-CD1 3.92Å; C40-F220 HydrophobicContact CB-CD2 4.06Å; C40-F220 HydrophobicContact CB-CE1 4.23Å; C40-F220 HydrophobicContact CB-CE2 4.35Å; C40-F220 HydrophobicContact CB-CG 3.83Å; C40-F220 HydrophobicContact CB-CZ 4.43Å
41	V	93.4	Very high	89.1	Confident	30 Å²	30	29.9 Å²	29.9	18%	0.182	14%	0.139	C	C	.	.	H	α-helix	trans	-69.4	-42.6	177.1	172.5	0	0	0	0	110.8	V37 I38 V39 L44 L45 V251 D255	V37-V41 HydrophobicContact CG1-CG2 4.31Å; V37-V41 VanDerWaalsContact O-CG2 3.32Å; V37-V41 WeakPolarHBondContact O-CG2 3.49Å; V37-V41 PolarHBondContact O-N 3.49Å; I38-V41 PolarHBondContact O-N 3.34Å; I38-V41 VanDerWaalsContact O-N 3.15Å; V39-V41 VanDerWaalsContact C-N 3.31Å; V39-V41 PolarHBondContact O-N 3.02Å; V41-L44 WeakPolarHBondContact O-CB 3.48Å; V41-L44 PolarHBondContact O-N 3.31Å; V41-L45 HydrophobicContact CG1-CD1 3.89Å; V41-L45 HydrophobicContact CG1-CG 4.27Å; V41-L45 WeakPolarHBondContact O-CB 3.03Å; V41-L45 VanDerWaalsContact O-CG 3.22Å; V41-L45 WeakPolarHBondContact O-CG 3.36Å; V41-L45 PolarHBondContact O-N 3.08Å; V41-V251 HydrophobicContact CG1-CG1 3.98Å; V41-D255 HydrophobicContact CG1-CB 3.89Å
42	A	92.9	Very high	89.3	Confident	1 Å²	1	27.1 Å²	27.1	1%	0.008	13%	0.126	C	C	.	.	H	α-helix	trans	-58.8	-49.1	176	0	0	0	0	0	112	I38 V39 L45 D46 L155 L159	I38-A42 WeakPolarHBondContact O-CB 3.3Å; I38-A42 PolarHBondContact O-N 2.97Å; V39-A42 PolarHBondContact O-N 3.22Å; A42-L45 PolarHBondContact O-N 2.71Å; A42-D46 PolarHBondContact O-N 3.33Å; A42-D46 VanDerWaalsContact O-N 3.09Å; A42-L155 HydrophobicContact CB-CD1 4.36Å; A42-L159 HydrophobicContact CB-CD2 3.87Å; A42-L159 HydrophobicContact CB-CG 4.36Å
43	L	91	Very high	89.2	Confident	1 Å²	1	22.3 Å²	22.3	1%	0.005	11%	0.108	C	C	.	.	H	α-helix	trans	-64.6	-39.9	177.5	-68.7	175.5	0	0	0	112.1	V39 L45 N47 D193 I197 A217 I221	V39-L43 HydrophobicContact CG1-CD1 3.87Å; V39-L43 HydrophobicContact CG1-CG 4.22Å; V39-L43 WeakPolarHBondContact O-CB 3.04Å; V39-L43 VanDerWaalsContact O-CG 3.27Å; V39-L43 WeakPolarHBondContact O-CG 3.49Å; V39-L43 PolarHBondContact O-N 2.85Å; L43-L45 VanDerWaalsContact C-N 3.34Å; L43-N47 PolarHBondContact O-N 2.98Å; L43-N47 PolarHBondContact O-ND2 3.37Å; L43-D193 HydrophobicContact CD2-CB 4.23Å; L43-D193 WeakPolarHBondContact CD2-OD1 3.41Å; L43-I197 HydrophobicContact CD1-CG1 4.47Å; L43-A217 HydrophobicContact CD1-CB 3.79Å; L43-I221 HydrophobicContact CB-CD1 4.48Å; L43-I221 HydrophobicContact CB-CG1 3.83Å; L43-I221 HydrophobicContact CD1-CD1 4.23Å; L43-I221 HydrophobicContact CD1-CG1 4.27Å; L43-I221 HydrophobicContact CD2-CD1 4.2Å; L43-I221 HydrophobicContact CD2-CG1 4.42Å; L43-I221 HydrophobicContact CG-CG1 4.4Å
44	L	91.7	Very high	88.8	Confident	26 Å²	26	14.2 Å²	14.2	14%	0.136	8%	0.078	C	C	.	.	H	α-helix	trans	-59.1	-47.1	173.6	179	77.9	0	0	0	110.9	C40 V41 N47 M48 F220 F223 G224	C40-L44 WeakPolarHBondContact O-CB 3.32Å; C40-L44 PolarHBondContact O-N 3.37Å; V41-L44 WeakPolarHBondContact O-CB 3.48Å; V41-L44 PolarHBondContact O-N 3.31Å; L44-N47 PolarHBondContact O-N 3.4Å; L44-M48 HydrophobicContact CG-CG 4.34Å; L44-M48 HydrophobicContact CG-SD 4.21Å; L44-M48 WeakPolarHBondContact O-CB 3.36Å; L44-M48 VanDerWaalsContact O-CG 3.29Å; L44-M48 WeakPolarHBondContact O-CG 3.48Å; L44-M48 PolarHBondContact O-N 2.89Å; L44-F220 HydrophobicContact CB-CD1 4.19Å; L44-F220 HydrophobicContact CD1-CD1 4.23Å; L44-F220 WeakPolarHBondContact CD1-O 3.38Å; L44-F220 HydrophobicContact CD2-CD1 4.38Å; L44-F223 HydrophobicContact CD1-CD1 3.59Å; L44-F223 HydrophobicContact CD1-CE1 4.33Å; L44-G224 VanDerWaalsContact CD1-CA 3.4Å
45	L	91.7	Very high	88.2	Confident	2 Å²	2	12.4 Å²	12.4	1%	0.01	7%	0.07	C	C	.	.	H	α-helix	trans	-64.2	-43.3	-176.8	-77.5	169.4	0	0	0	112.5	V41 A42 L43 N47 M48 L49 L248 V251 S252	V41-L45 HydrophobicContact CG1-CD1 3.89Å; V41-L45 HydrophobicContact CG1-CG 4.27Å; V41-L45 WeakPolarHBondContact O-CB 3.03Å; V41-L45 VanDerWaalsContact O-CG 3.22Å; V41-L45 WeakPolarHBondContact O-CG 3.36Å; V41-L45 PolarHBondContact O-N 3.08Å; A42-L45 PolarHBondContact O-N 2.71Å; L43-L45 VanDerWaalsContact C-N 3.34Å; L45-N47 VanDerWaalsContact C-N 3.34Å; L45-N47 PolarHBondContact O-N 3Å; L45-M48 PolarHBondContact O-N 3.25Å; L45-L49 WeakPolarHBondContact O-CB 3.19Å; L45-L49 VanDerWaalsContact O-CG 3.3Å; L45-L49 WeakPolarHBondContact O-CG 3.36Å; L45-L49 PolarHBondContact O-N 2.9Å; L45-L248 HydrophobicContact CD2-CD2 3.99Å; L45-V251 HydrophobicContact CD1-CG1 4.05Å; L45-V251 HydrophobicContact CD2-CB 3.89Å; L45-V251 HydrophobicContact CD2-CG1 3.8Å; L45-V251 HydrophobicContact CG-CG1 4.21Å; L45-S252 VanDerWaalsContact CD1-CA 3.49Å
46	D	91.3	Very high	87.7	Confident	4 Å²	4	12.2 Å²	12.2	2%	0.021	7%	0.069	C	C	.	.	H	α-helix	trans	-60.1	-47.9	178.5	-176.9	51.1	0	0	0	111.3	A42 M48 L49 Y50 K131 M162 S189	A42-D46 PolarHBondContact O-N 3.33Å; A42-D46 VanDerWaalsContact O-N 3.09Å; D46-M48 VanDerWaalsContact C-N 3.33Å; D46-M48 PolarHBondContact O-N 3.35Å; D46-L49 PolarHBondContact O-N 3.19Å; D46-Y50 WeakPolarHBondContact O-CB 3.49Å; D46-Y50 PolarHBondContact O-N 3.47Å; D46-K131 WeakPolarHBondContact OD1-CE 3.37Å; D46-K131 IonicContact OD1-NZ 2.95Å; D46-K131 PolarHBondContact OD1-NZ 2.97Å; D46-K131 VanDerWaalsContact OD1-NZ 3.15Å; D46-K131 IonicContact OD2-NZ 2.88Å; D46-K131 PolarHBondContact OD2-NZ 2.98Å; D46-M162 HydrophobicContact CB-SD 4.04Å; D46-S189 VanDerWaalsContact CG-OG 3.22Å; D46-S189 WeakPolarHBondContact OD1-CB 3.32Å; D46-S189 PolarHBondContact OD1-OG 3.5Å; D46-S189 PolarHBondContact OD2-OG 3.04Å
47	N	88.6	Confident	87.1	Confident	25 Å²	25	10.8 Å²	10.8	13%	0.134	6%	0.061	C	C	.	.	H	α-helix	trans	-66.5	-36.3	178.8	-75.8	-76.9	0	0	0	112.2	L43 L44 L45 M51 I221 S225	L43-N47 PolarHBondContact O-N 2.98Å; L43-N47 PolarHBondContact O-ND2 3.37Å; L44-N47 PolarHBondContact O-N 3.4Å; L45-N47 VanDerWaalsContact C-N 3.34Å; L45-N47 PolarHBondContact O-N 3Å; N47-M51 PolarHBondContact O-N 3.02Å; N47-I221 WeakPolarHBondContact ND2-CG2 3.44Å; N47-S225 WeakPolarHBondContact CB-OG 3.36Å; N47-S225 PolarHBondContact OD1-OG 3.37Å
48	M	90.2	Very high	86.3	Confident	19 Å²	19	8.9 Å²	8.9	9%	0.094	5%	0.051	C	C	.	.	H	α-helix	trans	-66	-47.4	174	-78.5	-163.9	77.9	0	0	112.1	L44 L45 D46 Y50 M51 V52 G224 V227 A228 F231 L248	L44-M48 HydrophobicContact CG-CG 4.34Å; L44-M48 HydrophobicContact CG-SD 4.21Å; L44-M48 WeakPolarHBondContact O-CB 3.36Å; L44-M48 VanDerWaalsContact O-CG 3.29Å; L44-M48 WeakPolarHBondContact O-CG 3.48Å; L44-M48 PolarHBondContact O-N 2.89Å; L45-M48 PolarHBondContact O-N 3.25Å; D46-M48 VanDerWaalsContact C-N 3.33Å; D46-M48 PolarHBondContact O-N 3.35Å; M48-Y50 PolarHBondContact O-N 3.01Å; M48-M51 PolarHBondContact O-N 3.49Å; M48-V52 WeakPolarHBondContact O-CB 3.33Å; M48-V52 VanDerWaalsContact O-CG1 3.27Å; M48-V52 WeakPolarHBondContact O-CG1 3.4Å; M48-V52 PolarHBondContact O-N 2.97Å; M48-G224 WeakPolarHBondContact CG-O 3.18Å; M48-V227 HydrophobicContact CE-CG1 4.42Å; M48-A228 HydrophobicContact CB-CB 4.17Å; M48-A228 HydrophobicContact CE-CB 4.45Å; M48-A228 HydrophobicContact CG-CB 4.19Å; M48-A228 WeakPolarHBondContact O-CB 3.44Å; M48-F231 HydrophobicContact CE-CB 4.01Å; M48-F231 HydrophobicContact CE-CD1 3.62Å; M48-F231 HydrophobicContact CE-CD2 4.29Å; M48-F231 HydrophobicContact CE-CE1 4.13Å; M48-F231 HydrophobicContact CE-CG 3.71Å; M48-L248 HydrophobicContact CB-CD2 4.14Å; M48-L248 HydrophobicContact CE-CD2 4.12Å; M48-L248 HydrophobicContact SD-CD2 4.14Å
49	L	88.1	Confident	85.3	Confident	0 Å²	0	10.3 Å²	10.3	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-61.9	-33.8	178.9	-77.1	167	0	0	0	112	L45 D46 I53 T166 L248	L45-L49 WeakPolarHBondContact O-CB 3.19Å; L45-L49 VanDerWaalsContact O-CG 3.3Å; L45-L49 WeakPolarHBondContact O-CG 3.36Å; L45-L49 PolarHBondContact O-N 2.9Å; D46-L49 PolarHBondContact O-N 3.19Å; L49-I53 VanDerWaalsContact O-CD1 3.23Å; L49-I53 WeakPolarHBondContact O-CD1 3.36Å; L49-I53 WeakPolarHBondContact O-CG1 3.04Å; L49-T166 WeakPolarHBondContact CD1-OG1 3.29Å; L49-T166 HydrophobicContact CD2-CG2 3.51Å; L49-T166 WeakPolarHBondContact CD2-OG1 3.38Å; L49-L248 HydrophobicContact CD2-CB 3.85Å; L49-L248 HydrophobicContact CD2-CD1 3.64Å; L49-L248 HydrophobicContact CD2-CG 4.37Å; L49-L248 HydrophobicContact CG-CB 4.42Å; L49-L248 HydrophobicContact CG-CD1 4.15Å
50	Y	84.1	Confident	84.4	Confident	9 Å²	9	10.8 Å²	10.8	4%	0.035	6%	0.06	C	C	.	.	H	α-helix	trans	-61.4	-53.8	175	-175.5	-112.4	0	0	0	112	D46 M48 K131 E309 Y432	D46-Y50 WeakPolarHBondContact O-CB 3.49Å; D46-Y50 PolarHBondContact O-N 3.47Å; M48-Y50 PolarHBondContact O-N 3.01Å; Y50-K131 HydrophobicContact CD2-CD 3.52Å; Y50-K131 HydrophobicContact CE2-CD 4.16Å; Y50-K131 HydrophobicContact CG-CD 4.44Å; Y50-E309 WeakPolarHBondContact CE1-OE2 3.42Å; Y50-Y432 AromaticContact CE1-CD1 3.75Å; Y50-Y432 HydrophobicContact CE1-CD1 3.75Å; Y50-Y432 AromaticContact CE1-CE1 3.61Å; Y50-Y432 HydrophobicContact CE1-CE1 3.61Å; Y50-Y432 HydrophobicContact CE1-CG 4.4Å; Y50-Y432 AromaticContact CZ-CD1 3.59Å; Y50-Y432 AromaticContact CZ-CE1 3.97Å; Y50-Y432 WeakPolarHBondContact OH-CD1 3.2Å
51	M	85.3	Confident	83.6	Confident	9 Å²	9	11.4 Å²	11.4	4%	0.044	6%	0.063	C	C	.	.	H	α-helix	trans	-85.9	-28.8	-169.5	-68.1	-68.7	-176.7	0	0	114.4	N47 M48 I53 V54 S225 A228 P229 E309	N47-M51 PolarHBondContact O-N 3.02Å; M48-M51 PolarHBondContact O-N 3.49Å; M51-I53 PolarHBondContact O-N 3.4Å; M51-V54 WeakPolarHBondContact O-CB 3.37Å; M51-V54 WeakPolarHBondContact O-CG2 3.49Å; M51-V54 PolarHBondContact O-N 3.01Å; M51-V54 VanDerWaalsContact O-N 3.11Å; M51-S225 WeakPolarHBondContact CB-O 3.25Å; M51-S225 VanDerWaalsContact CG-O 3.31Å; M51-S225 WeakPolarHBondContact CG-O 3.27Å; M51-A228 HydrophobicContact CB-CB 3.48Å; M51-A228 VanDerWaalsContact CB-CB 3.48Å; M51-P229 HydrophobicContact CB-CG 4.2Å; M51-E309 HydrophobicContact CE-CG 4.36Å; M51-E309 WeakPolarHBondContact CE-OE1 3.37Å; M51-E309 HydrophobicContact SD-CG 3.97Å
52	V	85.8	Confident	82.4	Confident	0 Å²	0	12.5 Å²	12.5	0%	0	8%	0.075	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.3	-23.5	-178.5	73.6	0	0	0	0	111.7	M48 P55 I56 A228 F231 P244 F245 L248	M48-V52 WeakPolarHBondContact O-CB 3.33Å; M48-V52 VanDerWaalsContact O-CG1 3.27Å; M48-V52 WeakPolarHBondContact O-CG1 3.4Å; M48-V52 PolarHBondContact O-N 2.97Å; V52-P55 WeakPolarHBondContact O-CD 3.38Å; V52-I56 HydrophobicContact CG2-CD1 4.43Å; V52-I56 VanDerWaalsContact O-CD1 3.26Å; V52-I56 WeakPolarHBondContact O-CD1 3.4Å; V52-I56 WeakPolarHBondContact O-CG1 3.45Å; V52-A228 HydrophobicContact CB-CB 4.21Å; V52-F231 HydrophobicContact CG2-CD1 3.91Å; V52-F231 HydrophobicContact CG2-CE1 4.4Å; V52-P244 HydrophobicContact CG2-CB 4.24Å; V52-F245 HydrophobicContact CG1-CE1 3.99Å; V52-L248 HydrophobicContact CB-CD1 4.29Å; V52-L248 HydrophobicContact CG1-CD1 3.78Å; V52-L248 HydrophobicContact CG2-CD1 4.32Å
53	I	81.4	Confident	81.3	Confident	0 Å²	0	17.5 Å²	17.5	0%	0	10%	0.098	C	C	.	.	T	Hydrogen-bonded Turn	trans	-82.8	-22	-175.9	-65.8	175.1	0	0	0	112.1	L49 M51 I56 V57 F128 F169 R182 F245	L49-I53 VanDerWaalsContact O-CD1 3.23Å; L49-I53 WeakPolarHBondContact O-CD1 3.36Å; L49-I53 WeakPolarHBondContact O-CG1 3.04Å; M51-I53 PolarHBondContact O-N 3.4Å; I53-I56 PolarHBondContact O-N 3.43Å; I53-V57 HydrophobicContact CG2-CB 3.74Å; I53-V57 HydrophobicContact CG2-CG2 3.12Å; I53-V57 PolarHBondContact O-N 3.42Å; I53-F128 HydrophobicContact CG2-CE1 4.4Å; I53-F128 HydrophobicContact CG2-CZ 4.14Å; I53-F169 HydrophobicContact CD1-CD1 4.37Å; I53-F169 HydrophobicContact CD1-CD2 4.35Å; I53-F169 HydrophobicContact CD1-CE1 3.94Å; I53-F169 HydrophobicContact CD1-CE2 3.91Å; I53-F169 HydrophobicContact CD1-CZ 3.69Å; I53-F169 HydrophobicContact CG1-CE1 4.16Å; I53-F169 HydrophobicContact CG1-CZ 4.13Å; I53-F169 HydrophobicContact CG2-CE1 4.41Å; I53-F169 HydrophobicContact CG2-CZ 3.83Å; I53-R182 VanDerWaalsContact CD1-NE 3.32Å; I53-F245 HydrophobicContact CD1-CE1 3.8Å; I53-F245 HydrophobicContact CD1-CZ 4.41Å; I53-F245 HydrophobicContact CG1-CE1 3.43Å; I53-F245 VanDerWaalsContact CG1-CE1 3.43Å; I53-F245 HydrophobicContact CG1-CZ 3.76Å
54	V	76.8	Confident	80.3	Confident	7 Å²	7	20 Å²	20	4%	0.042	11%	0.111	C	C	.	.	T	Hydrogen-bonded Turn	trans	-49.7	-54.3	179.5	174.1	0	0	0	0	112.5	M51 I56 P58 F128 E309	M51-V54 WeakPolarHBondContact O-CB 3.37Å; M51-V54 WeakPolarHBondContact O-CG2 3.49Å; M51-V54 PolarHBondContact O-N 3.01Å; M51-V54 VanDerWaalsContact O-N 3.11Å; V54-I56 VanDerWaalsContact C-N 3.32Å; V54-I56 PolarHBondContact O-N 3.42Å; V54-P58 WeakPolarHBondContact O-CD 3.33Å; V54-F128 HydrophobicContact CG2-CE1 3.75Å; V54-F128 HydrophobicContact CG2-CZ 4.13Å; V54-E309 WeakPolarHBondContact CG1-O 3.32Å; V54-E309 HydrophobicContact CG2-CB 4.2Å
55	P	73.9	Confident	79	Confident	13 Å²	13	26.2 Å²	26.2	8%	0.084	13%	0.132	C	C	.	.	T	Hydrogen-bonded Turn	trans	-72.9	-21.5	177.9	26.7	-33.9	0	0	0	114.1	V52	V52-P55 WeakPolarHBondContact O-CD 3.38Å
56	I	77.8	Confident	77.2	Confident	0 Å²	0	28.1 Å²	28.1	0%	0	15%	0.152	C	C	.	.	T	Hydrogen-bonded Turn	trans	-91.5	-43.1	-168.3	-59.5	174.7	0	0	0	112.4	V52 I53 V54 D59 Y60 Y236 P244 F245	V52-I56 HydrophobicContact CG2-CD1 4.43Å; V52-I56 VanDerWaalsContact O-CD1 3.26Å; V52-I56 WeakPolarHBondContact O-CD1 3.4Å; V52-I56 WeakPolarHBondContact O-CG1 3.45Å; I53-I56 PolarHBondContact O-N 3.43Å; V54-I56 VanDerWaalsContact C-N 3.32Å; V54-I56 PolarHBondContact O-N 3.42Å; I56-D59 PolarHBondContact O-N 2.88Å; I56-Y60 WeakPolarHBondContact O-CB 3.48Å; I56-Y60 PolarHBondContact O-N 3.47Å; I56-Y236 HydrophobicContact CB-CD2 4.46Å; I56-Y236 HydrophobicContact CD1-CD2 4.33Å; I56-Y236 HydrophobicContact CG1-CD2 3.98Å; I56-Y236 HydrophobicContact CG1-CG 4.19Å; I56-Y236 HydrophobicContact CG2-CD2 3.89Å; I56-Y236 HydrophobicContact CG2-CE2 3.85Å; I56-P244 HydrophobicContact CD1-CB 4.24Å; I56-P244 HydrophobicContact CD1-CG 4.05Å; I56-F245 HydrophobicContact CD1-CE2 4.06Å; I56-F245 HydrophobicContact CD1-CZ 3.83Å; I56-F245 HydrophobicContact CG2-CE2 4.17Å; I56-F245 HydrophobicContact CG2-CZ 4.3Å
57	V	77.7	Confident	74.9	Confident	0 Å²	0	31.2 Å²	31.2	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-61.7	-41.4	-168.6	142.9	0	0	0	0	115.3	I53 D59 Y60 I61 I124 L127 F128 F169	I53-V57 HydrophobicContact CG2-CB 3.74Å; I53-V57 HydrophobicContact CG2-CG2 3.12Å; I53-V57 PolarHBondContact O-N 3.42Å; V57-D59 VanDerWaalsContact C-N 3.29Å; V57-D59 PolarHBondContact O-N 2.98Å; V57-Y60 WeakPolarHBondContact O-CB 3.42Å; V57-Y60 PolarHBondContact O-N 3.37Å; V57-I61 HydrophobicContact CG1-CD1 3.98Å; V57-I61 WeakPolarHBondContact O-CG1 3.42Å; V57-I61 PolarHBondContact O-N 3.2Å; V57-I124 HydrophobicContact CG1-CG1 4.2Å; V57-I124 HydrophobicContact CG1-CG2 4.08Å; V57-L127 HydrophobicContact CG1-CD2 3.98Å; V57-L127 HydrophobicContact CG2-CD2 3.88Å; V57-F128 HydrophobicContact CB-CE2 4.34Å; V57-F128 HydrophobicContact CB-CZ 4.4Å; V57-F128 HydrophobicContact CG1-CE2 3.94Å; V57-F128 HydrophobicContact CG1-CZ 4.48Å; V57-F169 HydrophobicContact CG2-CZ 3.89Å
58	P	73.7	Confident	72.4	Confident	37 Å²	37	33.3 Å²	33.3	24%	0.24	21%	0.213	C	C	.	.	H	α-helix	trans	-57.5	-44.2	179.1	-26.3	35.5	0	0	0	112.1	V54 A62 I124	V54-P58 WeakPolarHBondContact O-CD 3.33Å; P58-A62 PolarHBondContact O-N 3.5Å; P58-I124 HydrophobicContact CB-CD1 4.22Å; P58-I124 HydrophobicContact CG-CD1 4.39Å
59	D	71.2	Confident	70.1	Confident	30 Å²	30	40.9 Å²	40.9	16%	0.16	25%	0.248	C	C	.	.	H	α-helix	trans	-73.1	-35	178.2	-166.7	41.7	0	0	0	111.9	I56 V57 I61 A62 H63 Y236	I56-D59 PolarHBondContact O-N 2.88Å; V57-D59 VanDerWaalsContact C-N 3.29Å; V57-D59 PolarHBondContact O-N 2.98Å; D59-I61 PolarHBondContact O-N 3.08Å; D59-A62 PolarHBondContact O-N 2.89Å; D59-H63 VanDerWaalsContact CG-CE1 3.41Å; D59-H63 PolarHBondContact O-N 3.47Å; D59-H63 PolarHBondContact O-ND1 2.8Å; D59-H63 IonicContact OD1-CE1 2.95Å; D59-H63 PolarHBondContact OD1-CE1 3.29Å; D59-H63 IonicContact OD1-ND1 3.75Å; D59-H63 PolarHBondContact OD1-ND1 3.02Å; D59-H63 IonicContact OD2-CE1 3.86Å; D59-H63 PolarHBondContact OD2-CE1 3.25Å; D59-H63 IonicContact OD2-ND1 3.19Å; D59-H63 PolarHBondContact OD2-ND1 3.29Å; D59-Y236 PolarHBondContact OD2-OH 3.45Å
60	Y	73.6	Confident	67.3	Low	9 Å²	9	43.9 Å²	43.9	4%	0.035	28%	0.279	C	S	.	.	H	α-helix	trans	-60.3	-43	176.6	-157.5	-104.6	0	0	0	112.6	I56 V57 M64 A172 L178 K241	I56-Y60 WeakPolarHBondContact O-CB 3.48Å; I56-Y60 PolarHBondContact O-N 3.47Å; V57-Y60 WeakPolarHBondContact O-CB 3.42Å; V57-Y60 PolarHBondContact O-N 3.37Å; Y60-M64 HydrophobicContact CD1-CE 3.49Å; Y60-M64 VanDerWaalsContact CD1-CE 3.49Å; Y60-M64 HydrophobicContact CE1-CE 3.08Å; Y60-M64 WeakPolarHBondContact O-CG 3.42Å; Y60-M64 PolarHBondContact O-N 2.97Å; Y60-A172 WeakPolarHBondContact CE1-O 3.4Å; Y60-A172 VanDerWaalsContact CZ-O 3.32Å; Y60-A172 PolarHBondContact OH-O 3.11Å; Y60-L178 HydrophobicContact CD1-CD1 3.68Å; Y60-L178 HydrophobicContact CD1-CD2 3.99Å; Y60-L178 HydrophobicContact CD1-CG 4.36Å; Y60-L178 HydrophobicContact CE1-CD1 3.86Å; Y60-L178 HydrophobicContact CE1-CD2 3.65Å; Y60-L178 HydrophobicContact CE1-CG 4.09Å; Y60-K241 HydrophobicContact CD2-CB 4.29Å; Y60-K241 HydrophobicContact CD2-CD 4.19Å; Y60-K241 HydrophobicContact CE2-CB 4.15Å; Y60-K241 HydrophobicContact CE2-CD 3.7Å; Y60-K241 HydrophobicContact CE2-CG 4.09Å
61	I	74.7	Confident	65	Low	18 Å²	18	49.2 Å²	49.2	9%	0.092	32%	0.315	C	S	.	.	H	α-helix	trans	-70.7	-38.7	177.2	-67.7	175.6	0	0	0	110.9	V57 D59 H63 M64 R65 I124 L127 Y175	V57-I61 HydrophobicContact CG1-CD1 3.98Å; V57-I61 WeakPolarHBondContact O-CG1 3.42Å; V57-I61 PolarHBondContact O-N 3.2Å; D59-I61 PolarHBondContact O-N 3.08Å; I61-H63 VanDerWaalsContact C-N 3.35Å; I61-H63 PolarHBondContact O-N 3.2Å; I61-M64 PolarHBondContact O-N 3.37Å; I61-R65 PolarHBondContact O-N 3.5Å; I61-I124 HydrophobicContact CD1-CG1 3.76Å; I61-L127 HydrophobicContact CD1-CD2 4.38Å; I61-Y175 HydrophobicContact CD1-CD2 4.46Å; I61-Y175 HydrophobicContact CD1-CE2 4.49Å
62	A	69.6	Low	62.2	Low	52 Å²	52	55 Å²	55	43%	0.43	35%	0.351	S	S	.	.	H	α-helix	trans	-61	-43.5	176	0	0	0	0	0	111.8	P58 D59 M64 R65 G66	P58-A62 PolarHBondContact O-N 3.5Å; D59-A62 PolarHBondContact O-N 2.89Å; A62-M64 PolarHBondContact O-N 3.36Å; A62-R65 PolarHBondContact O-N 3.48Å; A62-G66 PolarHBondContact O-N 3.31Å; A62-G66 VanDerWaalsContact O-N 3.11Å
63	H	69.8	Low	59.7	Low	106 Å²	106	66.4 Å²	66.4	49%	0.491	39%	0.394	S	S	.	.	H	α-helix	trans	-63.1	-39.3	177.8	-82.8	85.4	0	0	0	113.5	D59 I61 R65 G66 G67	D59-H63 VanDerWaalsContact CG-CE1 3.41Å; D59-H63 PolarHBondContact O-N 3.47Å; D59-H63 PolarHBondContact O-ND1 2.8Å; D59-H63 IonicContact OD1-CE1 2.95Å; D59-H63 PolarHBondContact OD1-CE1 3.29Å; D59-H63 IonicContact OD1-ND1 3.75Å; D59-H63 PolarHBondContact OD1-ND1 3.02Å; D59-H63 IonicContact OD2-CE1 3.86Å; D59-H63 PolarHBondContact OD2-CE1 3.25Å; D59-H63 IonicContact OD2-ND1 3.19Å; D59-H63 PolarHBondContact OD2-ND1 3.29Å; I61-H63 VanDerWaalsContact C-N 3.35Å; I61-H63 PolarHBondContact O-N 3.2Å; H63-R65 PolarHBondContact O-N 3.14Å; H63-G66 PolarHBondContact O-N 2.84Å; H63-G67 PolarHBondContact O-N 2.91Å
64	M	70	Confident	57.1	Low	55 Å²	55	72.1 Å²	72.1	27%	0.271	43%	0.429	S	S	.	.	H	α-helix	trans	-61.5	-34.4	176.3	-72.4	-177.6	-175.8	0	0	112.4	Y60 I61 A62 A172 E173 L178	Y60-M64 HydrophobicContact CD1-CE 3.49Å; Y60-M64 VanDerWaalsContact CD1-CE 3.49Å; Y60-M64 HydrophobicContact CE1-CE 3.08Å; Y60-M64 WeakPolarHBondContact O-CG 3.42Å; Y60-M64 PolarHBondContact O-N 2.97Å; I61-M64 PolarHBondContact O-N 3.37Å; A62-M64 PolarHBondContact O-N 3.36Å; M64-A172 VanDerWaalsContact CE-O 3.25Å; M64-A172 WeakPolarHBondContact CE-O 3.47Å; M64-E173 VanDerWaalsContact SD-O 3.35Å; M64-L178 HydrophobicContact CE-CD1 3.64Å; M64-L178 HydrophobicContact CE-CG 4.19Å; M64-L178 HydrophobicContact SD-CD1 4.21Å
65	R	63.1	Low	54.8	Low	155 Å²	155	77.1 Å²	77.1	59%	0.585	46%	0.461	S	S	*	.	H	α-helix	trans	-77.4	-35.1	-179.9	-157.6	176.4	-178.4	177.4	0.1	112	I61 A62 H63 G67 T117 E120	I61-R65 PolarHBondContact O-N 3.5Å; A62-R65 PolarHBondContact O-N 3.48Å; H63-R65 PolarHBondContact O-N 3.14Å; R65-G67 PolarHBondContact O-N 3.47Å; R65-T117 PolarHBondContact NH1-OG1 3.13Å; R65-T117 VanDerWaalsContact NH1-OG1 3.15Å; R65-E120 IonicContact CZ-OE1 2.68Å; R65-E120 IonicContact NH1-OE1 3.35Å; R65-E120 PolarHBondContact NH1-OE1 3.2Å
66	G	54.3	Low	52.7	Low	42 Å²	42	85.3 Å²	85.3	43%	0.433	50%	0.499	S	S	.	.	H	α-helix	trans	-69.7	-14.4	173.4	0	0	0	0	0	114.3	A62 H63 G68 E69	A62-G66 PolarHBondContact O-N 3.31Å; A62-G66 VanDerWaalsContact O-N 3.11Å; H63-G66 PolarHBondContact O-N 2.84Å; G66-G68 PolarHBondContact O-N 3.29Å; G66-E69 CarbonylContact O-C 3.5Å; G66-E69 PolarHBondContact O-N 2.97Å
67	G	42.5	Very low	50.3	Low	69 Å²	69	91 Å²	91	71%	0.711	53%	0.533	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.8	-6.6	176.8	0	0	0	0	0	115.6	H63 R65	H63-G67 PolarHBondContact O-N 2.91Å; R65-G67 PolarHBondContact O-N 3.47Å
68	G	37.9	Very low	47.9	Very low	70 Å²	70	102.5 Å²	102.5	72%	0.722	58%	0.577	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88.7	-16	173.6	0	0	0	0	0	114.8	G66	G66-G68 PolarHBondContact O-N 3.29Å
69	E	40.3	Very low	45.7	Very low	177 Å²	177	109 Å²	109	83%	0.827	60%	0.604	S	S	*	*	S	Bend	trans	-140.5	100.1	174.8	-73.8	-177.2	150	0	0	107.7	G66	G66-E69 CarbonylContact O-C 3.5Å; G66-E69 PolarHBondContact O-N 2.97Å
70	G	29	Very low	43.7	Very low	64 Å²	64	113.3 Å²	113.3	66%	0.66	63%	0.634	S	S	*	*			trans	-55.7	145	-173.6	0	0	0	0	0	113.2	T72	G70-T72 PolarHBondContact O-N 3.43Å; G70-T72 VanDerWaalsContact O-N 3.12Å
71	P	36.3	Very low	41.7	Very low	121 Å²	121	119.6 Å²	119.6	79%	0.786	67%	0.673	S	S	*	*			trans	-77	103.1	170.7	30.3	-28.5	0	0	0	107.9	R73	P71-R73 PolarHBondContact O-N 2.92Å
72	T	27.8	Very low	39.8	Very low	131 Å²	131	126.5 Å²	126.5	80%	0.804	71%	0.709	S	S	*	*			trans	-60.4	96.7	151.8	29.8	0	0	0	0	107.1	G70 T74	G70-T72 PolarHBondContact O-N 3.43Å; G70-T72 VanDerWaalsContact O-N 3.12Å; T72-T74 PolarHBondContact O-N 3.42Å
73	R	31.6	Very low	38.1	Very low	239 Å²	239	129.6 Å²	129.6	90%	0.902	73%	0.725	S	S	*	*			trans	-57.6	92.7	157.9	-85.6	179	163.2	163.9	-4.5	107.2	P71	P71-R73 PolarHBondContact O-N 2.92Å
74	T	26.9	Very low	36.6	Very low	119 Å²	119	132.4 Å²	132.4	73%	0.73	74%	0.743	S	S	*	*			trans	-75.4	126.8	152.7	48.1	0	0	0	0	106.6	T72 E76	T72-T74 PolarHBondContact O-N 3.42Å; T74-E76 PolarHBondContact O-N 3.41Å
75	P	29.3	Very low	35	Very low	112 Å²	112	135.8 Å²	135.8	73%	0.727	77%	0.769	S	S	*	*			trans	-60.6	130.6	177.6	25.6	-31.1	0	0	0	108.8	V77	P75-V77 PolarHBondContact O-N 3.35Å
76	E	30.6	Very low	33.8	Very low	186 Å²	186	133.9 Å²	133.9	87%	0.869	78%	0.775	S	S	*	*			trans	-54.4	105.2	167	-86.2	179.1	137.3	0	0	108.5	T74 W78	T74-E76 PolarHBondContact O-N 3.41Å; E76-W78 PolarHBondContact O-N 2.97Å
77	V	25.6	Very low	33.1	Very low	120 Å²	120	138.6 Å²	138.6	73%	0.727	80%	0.798	S	S	*	*			trans	-76.3	113.5	159.8	175.6	0	0	0	0	105.4	P75 E79	P75-V77 PolarHBondContact O-N 3.35Å; V77-E79 PolarHBondContact O-N 3.37Å
78	W	28.6	Very low	32.9	Very low	240 Å²	240	138.9 Å²	138.9	91%	0.909	79%	0.794	S	S	*	*			trans	-60	102.4	164.7	-84.5	-13.3	0	0	0	108.8	E76	E76-W78 PolarHBondContact O-N 2.97Å
79	E	26.4	Very low	33.2	Very low	173 Å²	173	142.9 Å²	142.9	81%	0.808	80%	0.798	S	S	*	*			trans	-79.7	127	159.6	-75.4	-165.3	165.3	0	0	108.9	V77 T81	V77-E79 PolarHBondContact O-N 3.37Å; E79-T81 PolarHBondContact O-N 2.9Å
80	P	29.6	Very low	33.1	Very low	121 Å²	121	139.5 Å²	139.5	79%	0.786	80%	0.801	S	S	*	*			trans	-65.4	124.6	174.9	-13	26.4	0	0	0	109.7	L82	P80-L82 PolarHBondContact O-N 3.32Å; P80-L82 VanDerWaalsContact O-N 3.08Å
81	T	32.5	Very low	33.4	Very low	141 Å²	141	142 Å²	142	87%	0.865	81%	0.808	S	S	*	*			trans	-57.5	110.1	170.6	16.8	0	0	0	0	110.3	E79	E79-T81 PolarHBondContact O-N 2.9Å
82	L	35.1	Very low	33.6	Very low	163 Å²	163	140.3 Å²	140.3	85%	0.853	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-64	136.7	166	-83.9	158.9	0	0	0	109.7	P80	P80-L82 PolarHBondContact O-N 3.32Å; P80-L82 VanDerWaalsContact O-N 3.08Å
83	P	34	Very low	34.1	Very low	118 Å²	118	145.3 Å²	145.3	77%	0.766	81%	0.81	S	S	*	*	P	Polyproline II helix	trans	-70.5	145.3	179.1	26.6	-31.3	0	0	0	112.2
84	L	37.3	Very low	34.2	Very low	165 Å²	165	138.6 Å²	138.6	86%	0.864	81%	0.806	S	S	*	*	P	Polyproline II helix	trans	-50.3	138.1	176.4	-75.7	140.8	0	0	0	112.5	T86	L84-T86 PolarHBondContact O-N 3.32Å
85	P	35.4	Very low	34.8	Very low	125 Å²	125	137 Å²	137	81%	0.812	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-74.3	124.4	176.9	28.1	-30.6	0	0	0	111.4
86	T	38.2	Very low	35.1	Very low	116 Å²	116	139.1 Å²	139.1	71%	0.712	81%	0.81	S	S	*	*	P	Polyproline II helix	trans	-67.1	150.7	166.5	38.8	0	0	0	0	111.9	L84 A88	L84-T86 PolarHBondContact O-N 3.32Å; T86-A88 PolarHBondContact O-N 3.22Å
87	P	41	Very low	35.3	Very low	140 Å²	140	137.6 Å²	137.6	91%	0.909	81%	0.813	S	S	*	*	T	Hydrogen-bonded Turn	trans	-81.4	54.6	-170	35.3	-36.6	0	0	0	113.3
88	A	37.8	Very low	35.6	Very low	76 Å²	76	137.9 Å²	137.9	63%	0.628	82%	0.82	S	S	*	*	T	Hydrogen-bonded Turn	trans	-117.8	-15.4	-178.9	0	0	0	0	0	115.2	T86	T86-A88 PolarHBondContact O-N 3.22Å
89	N	43.3	Very low	35.8	Very low	154 Å²	154	131.2 Å²	131.2	82%	0.824	82%	0.817	S	S	*	*			trans	-124.9	48.3	-173.5	-70.9	-9.4	0	0	0	113.4	S91	N89-S91 PolarHBondContact O-N 3.15Å
90	A	39	Very low	36	Very low	106 Å²	106	128.3 Å²	128.3	88%	0.876	82%	0.816	S	S	*	*			trans	-87.5	11.4	-178.7	0	0	0	0	0	115.2
91	S	35.6	Very low	36.7	Very low	115 Å²	115	127.6 Å²	127.6	80%	0.804	81%	0.811	S	S	*	*	S	Bend	trans	-115.6	6.8	-170	51	0	0	0	0	116.5	N89	N89-S91 PolarHBondContact O-N 3.15Å
92	A	40.4	Very low	36.8	Very low	86 Å²	86	127.9 Å²	127.9	71%	0.711	81%	0.813	S	S	*	*	S	Bend	trans	-113.4	3.2	-173.4	0	0	0	0	0	116.8
93	Y	37.5	Very low	36.6	Very low	236 Å²	236	124.6 Å²	124.6	93%	0.925	81%	0.809	S	S	*	*	S	Bend	trans	-124.2	26.1	-179.2	-92.8	-82	0	0	0	114.4
94	A	34.8	Very low	36.6	Very low	99 Å²	99	124 Å²	124	82%	0.818	81%	0.814	S	S	*	*			trans	-107.4	58.3	173.5	0	0	0	0	0	111.3
95	A	39	Very low	36.1	Very low	84 Å²	84	127.2 Å²	127.2	69%	0.694	82%	0.815	S	S	*	*	S	Bend	trans	-161.8	89.7	165.8	0	0	0	0	0	110.6
96	N	36.1	Very low	36	Very low	158 Å²	158	127.2 Å²	127.2	85%	0.845	82%	0.815	S	S	*	*			trans	152.5	87.5	143.4	-80	-8.7	0	0	0	110.7
97	T	33.2	Very low	35.7	Very low	153 Å²	153	126.3 Å²	126.3	94%	0.939	82%	0.819	S	S	*	*			trans	-159.2	91.1	153.5	13.7	0	0	0	0	110.2
98	S	32.2	Very low	35.3	Very low	126 Å²	126	123.1 Å²	123.1	88%	0.881	81%	0.811	S	S	*	*			trans	-111.1	92.9	158.8	56.7	0	0	0	0	108.1
99	A	33.3	Very low	35	Very low	101 Å²	101	124.4 Å²	124.4	84%	0.835	82%	0.816	S	S	*	*			trans	-178.7	117.4	156.3	0	0	0	0	0	110.6
100	S	29.6	Very low	34.7	Very low	112 Å²	112	121 Å²	121	78%	0.783	81%	0.809	S	S	*	*			trans	-97.1	-179.9	164.4	49.3	0	0	0	0	109.8
101	P	45.8	Very low	34.8	Very low	105 Å²	105	123.8 Å²	123.8	68%	0.682	81%	0.808	S	S	*	*			cis	-130.6	149.9	-50	34.8	-19.6	0	0	0	111.3
102	T	34.1	Very low	34.5	Very low	148 Å²	148	128.7 Å²	128.7	91%	0.908	81%	0.809	S	S	*	*			trans	155.4	95.7	148.3	34.6	0	0	0	0	110.6
103	A	32	Very low	34.3	Very low	94 Å²	94	130.5 Å²	130.5	78%	0.777	81%	0.814	S	S	*	*			trans	-162.2	110.6	152.6	0	0	0	0	0	107.1	R105	A103-R105 PolarHBondContact O-N 3.16Å; A103-R105 VanDerWaalsContact O-N 3.09Å
104	A	32.2	Very low	34.2	Very low	105 Å²	105	130.5 Å²	130.5	87%	0.868	81%	0.812	S	S	*	*			trans	-56.1	113.2	172.7	0	0	0	0	0	109
105	R	28.7	Very low	34.4	Very low	232 Å²	232	135.2 Å²	135.2	88%	0.875	81%	0.81	S	S	*	*			trans	-69.1	126.8	165.8	-68.7	171.6	105.1	149.8	2.2	106.8	A103 A107	A103-R105 PolarHBondContact O-N 3.16Å; A103-R105 VanDerWaalsContact O-N 3.09Å; R105-A107 PolarHBondContact O-N 3.05Å; R105-A107 VanDerWaalsContact O-N 3.16Å
106	P	32.8	Very low	34.8	Very low	125 Å²	125	132.6 Å²	132.6	81%	0.812	79%	0.786	S	S	*	*			trans	-62.8	122.4	164.6	27	-29	0	0	0	106.2	G108	P106-G108 PolarHBondContact O-N 3.48Å
107	A	31.8	Very low	35.6	Very low	97 Å²	97	127.9 Å²	127.9	80%	0.802	76%	0.763	S	S	*	*			trans	-54	113.3	173.1	0	0	0	0	0	107.5	R105 S109	R105-A107 PolarHBondContact O-N 3.05Å; R105-A107 VanDerWaalsContact O-N 3.16Å; A107-S109 PolarHBondContact O-N 3.36Å
108	G	31.6	Very low	36.4	Very low	73 Å²	73	127.9 Å²	127.9	75%	0.753	75%	0.752	S	S	*	*			trans	-54.2	108.5	167.7	0	0	0	0	0	107	P106 A110	P106-G108 PolarHBondContact O-N 3.48Å; G108-A110 VanDerWaalsContact C-N 3.27Å; G108-A110 PolarHBondContact O-N 3.29Å
109	S	32.7	Very low	37.9	Very low	103 Å²	103	124.3 Å²	124.3	72%	0.72	73%	0.727	S	S	*	*			trans	-53.3	96.2	168.8	152.4	0	0	0	0	107.2	A107 L111	A107-S109 PolarHBondContact O-N 3.36Å; S109-L111 PolarHBondContact O-N 3.43Å
110	A	35.8	Very low	39.5	Very low	82 Å²	82	121.1 Å²	121.1	68%	0.678	70%	0.695	S	S	*	*			trans	-53.4	110.1	162.6	0	0	0	0	0	106.1	G108 R112	G108-A110 VanDerWaalsContact C-N 3.27Å; G108-A110 PolarHBondContact O-N 3.29Å; A110-R112 PolarHBondContact O-N 2.98Å
111	L	41.1	Very low	41.4	Very low	166 Å²	166	117.3 Å²	117.3	87%	0.869	67%	0.666	S	S	*	*			trans	-65.7	80.2	176.1	-144.8	88.9	0	0	0	107.2	S109	S109-L111 PolarHBondContact O-N 3.43Å
112	R	29.6	Very low	42.9	Very low	217 Å²	217	115.2 Å²	115.2	82%	0.819	65%	0.651	S	S	*	*	P	Polyproline II helix	trans	-67.8	125.6	168.5	-74.4	-175.8	168.9	-172.1	-3.2	106.3	A110 R114	A110-R112 PolarHBondContact O-N 2.98Å; R112-R114 PolarHBondContact O-N 2.94Å
113	P	36.6	Very low	45	Very low	125 Å²	125	112.3 Å²	112.3	81%	0.812	63%	0.626	S	S	*	*	P	Polyproline II helix	trans	-56.5	117.5	169.4	-18	29.8	0	0	0	107.6	Y115	P113-Y115 PolarHBondContact O-N 3.32Å
114	R	35.6	Very low	47.3	Very low	236 Å²	236	108.5 Å²	108.5	89%	0.891	59%	0.592	S	S	*	*	P	Polyproline II helix	trans	-74.2	120.3	-174.5	-146.2	172.4	-171.6	167.3	0.9	106.9	R112	R112-R114 PolarHBondContact O-N 2.94Å
115	Y	38.8	Very low	49.6	Very low	198 Å²	198	103.6 Å²	103.6	78%	0.776	55%	0.552	S	S	*	*	P	Polyproline II helix	trans	-47.8	147.1	168.4	-80.8	-95.9	0	0	0	110.2	P113 T117	P113-Y115 PolarHBondContact O-N 3.32Å; Y115-T117 PolarHBondContact O-N 3.42Å
116	P	47.6	Very low	52.4	Low	29 Å²	29	95.3 Å²	95.3	19%	0.188	53%	0.527	C	S	.	.	P	Polyproline II helix	trans	-53.9	120.8	158.8	10	-7.8	0	0	0	107	E118 E120	P116-E118 PolarHBondContact O-N 2.88Å; P116-E120 WeakPolarHBondContact CA-OE2 3.42Å; P116-E120 HydrophobicContact CB-CB 3.97Å; P116-E120 VanDerWaalsContact CB-OE2 3.24Å; P116-E120 WeakPolarHBondContact CB-OE2 3.41Å
117	T	52.1	Low	54.9	Low	58 Å²	58	89.3 Å²	89.3	36%	0.356	49%	0.489	S	S	.	.	P	Polyproline II helix	trans	-54.6	141.7	176.1	39.3	0	0	0	0	108.7	R65 Y115 S119 E120	R65-T117 PolarHBondContact NH1-OG1 3.13Å; R65-T117 VanDerWaalsContact NH1-OG1 3.15Å; Y115-T117 PolarHBondContact O-N 3.42Å; T117-S119 CarbonylContact O-C 3.55Å; T117-S119 PolarHBondContact O-N 3.24Å; T117-S119 PolarHBondContact OG1-OG 3.15Å; T117-E120 PolarHBondContact O-N 3.39Å
118	E	51.5	Low	57.5	Low	153 Å²	153	84.8 Å²	84.8	72%	0.715	45%	0.451	S	S	*	.	T	Hydrogen-bonded Turn	trans	-41.8	-24.5	-179.1	-64.5	-178.4	157.3	0	0	115	P116 V122	P116-E118 PolarHBondContact O-N 2.88Å; E118-V122 VanDerWaalsContact O-CG2 3.24Å; E118-V122 WeakPolarHBondContact O-CG2 3.28Å
119	S	62.5	Low	60.2	Low	51 Å²	51	81.3 Å²	81.3	36%	0.357	42%	0.415	S	S	.	.	H	α-helix	trans	-69.8	-20.9	172.8	74.2	0	0	0	0	116.4	T117 K123	T117-S119 CarbonylContact O-C 3.55Å; T117-S119 PolarHBondContact O-N 3.24Å; T117-S119 PolarHBondContact OG1-OG 3.15Å; S119-K123 WeakPolarHBondContact O-CB 3.37Å; S119-K123 VanDerWaalsContact O-CD 3.25Å; S119-K123 WeakPolarHBondContact O-CD 3.36Å; S119-K123 WeakPolarHBondContact O-CG 3.32Å; S119-K123 PolarHBondContact O-N 2.88Å; S119-K123 VanDerWaalsContact O-N 3.13Å
120	E	67.7	Low	63	Low	34 Å²	34	76.7 Å²	76.7	16%	0.159	38%	0.382	C	S	.	.	H	α-helix	trans	-85.1	-49.6	-170.5	-74.9	-178.4	167.2	0	0	112.6	R65 P116 T117 V122 K123 I124	R65-E120 IonicContact CZ-OE1 2.68Å; R65-E120 IonicContact NH1-OE1 3.35Å; R65-E120 PolarHBondContact NH1-OE1 3.2Å; P116-E120 WeakPolarHBondContact CA-OE2 3.42Å; P116-E120 HydrophobicContact CB-CB 3.97Å; P116-E120 VanDerWaalsContact CB-OE2 3.24Å; P116-E120 WeakPolarHBondContact CB-OE2 3.41Å; T117-E120 PolarHBondContact O-N 3.39Å; E120-V122 PolarHBondContact O-N 3.47Å; E120-K123 WeakPolarHBondContact O-CB 3.32Å; E120-K123 PolarHBondContact O-N 3.35Å; E120-K123 VanDerWaalsContact O-N 3.09Å; E120-I124 WeakPolarHBondContact O-CG1 3.22Å; E120-I124 PolarHBondContact O-N 3.49Å
121	D	69.7	Low	65.7	Low	33 Å²	33	73.2 Å²	73.2	18%	0.176	35%	0.352	C	S	.	.	H	α-helix	trans	-63.4	-34.6	175.5	-65.2	-31.1	0	0	0	111	I124 G125 H444	D121-I124 PolarHBondContact O-N 2.93Å; D121-G125 PolarHBondContact O-N 2.84Å; D121-H444 WeakPolarHBondContact CB-NE2 3.18Å; D121-H444 IonicContact OD2-CE1 3.09Å; D121-H444 PolarHBondContact OD2-CE1 2.91Å; D121-H444 IonicContact OD2-NE2 3.93Å; D121-H444 PolarHBondContact OD2-NE2 3.46Å
122	V	75.6	Confident	68.1	Low	60 Å²	60	65.4 Å²	65.4	36%	0.364	31%	0.312	S	S	.	.	H	α-helix	trans	-65.5	-43	172.3	176.2	0	0	0	0	111.4	E118 E120 G125 V126	E118-V122 VanDerWaalsContact O-CG2 3.24Å; E118-V122 WeakPolarHBondContact O-CG2 3.28Å; E120-V122 PolarHBondContact O-N 3.47Å; V122-G125 PolarHBondContact O-N 2.94Å; V122-V126 HydrophobicContact CG1-CG2 4.37Å; V122-V126 WeakPolarHBondContact O-CB 3.35Å; V122-V126 VanDerWaalsContact O-CG2 3.22Å; V122-V126 WeakPolarHBondContact O-CG2 3.49Å; V122-V126 PolarHBondContact O-N 2.86Å
123	K	79.8	Confident	71.1	Confident	88 Å²	88	58.5 Å²	58.5	38%	0.383	29%	0.29	S	S	.	.	H	α-helix	trans	-63.7	-42.3	175.2	-80.7	167.5	-170.1	175.6	0	111.9	S119 E120 L127 Y175	S119-K123 WeakPolarHBondContact O-CB 3.37Å; S119-K123 VanDerWaalsContact O-CD 3.25Å; S119-K123 WeakPolarHBondContact O-CD 3.36Å; S119-K123 WeakPolarHBondContact O-CG 3.32Å; S119-K123 PolarHBondContact O-N 2.88Å; S119-K123 VanDerWaalsContact O-N 3.13Å; E120-K123 WeakPolarHBondContact O-CB 3.32Å; E120-K123 PolarHBondContact O-N 3.35Å; E120-K123 VanDerWaalsContact O-N 3.09Å; K123-L127 VanDerWaalsContact O-CB 3.28Å; K123-L127 WeakPolarHBondContact O-CB 3.48Å; K123-L127 PolarHBondContact O-N 2.98Å; K123-Y175 HydrophobicContact CB-CE2 3.81Å; K123-Y175 HydrophobicContact CG-CE2 4.18Å; K123-Y175 PolarHBondContact O-OH 3.21Å; K123-Y175 VanDerWaalsContact O-OH 3.06Å
124	I	79.9	Confident	73.7	Confident	13 Å²	13	55 Å²	55	7%	0.067	26%	0.264	C	S	.	.	H	α-helix	trans	-61.5	-50.8	176	-67.9	165.1	0	0	0	109.4	V57 P58 I61 E120 D121 V126 L127 F128	V57-I124 HydrophobicContact CG1-CG1 4.2Å; V57-I124 HydrophobicContact CG1-CG2 4.08Å; P58-I124 HydrophobicContact CB-CD1 4.22Å; P58-I124 HydrophobicContact CG-CD1 4.39Å; I61-I124 HydrophobicContact CD1-CG1 3.76Å; E120-I124 WeakPolarHBondContact O-CG1 3.22Å; E120-I124 PolarHBondContact O-N 3.49Å; D121-I124 PolarHBondContact O-N 2.93Å; I124-V126 PolarHBondContact O-N 2.88Å; I124-L127 WeakPolarHBondContact O-CB 3.5Å; I124-L127 PolarHBondContact O-N 3.33Å; I124-L127 VanDerWaalsContact O-N 3.11Å; I124-F128 HydrophobicContact CG2-CD2 3.74Å; I124-F128 HydrophobicContact CG2-CE2 3.63Å; I124-F128 VanDerWaalsContact O-CD2 3.26Å; I124-F128 WeakPolarHBondContact O-CD2 3.42Å; I124-F128 PolarHBondContact O-N 3.27Å
125	G	80.8	Confident	76.4	Confident	3 Å²	3	44.2 Å²	44.2	3%	0.031	22%	0.224	C	C	.	.	H	α-helix	trans	-57.5	-47.1	178.3	0	0	0	0	0	113	D121 V122 L127 F128 A129 P436	D121-G125 PolarHBondContact O-N 2.84Å; V122-G125 PolarHBondContact O-N 2.94Å; G125-L127 VanDerWaalsContact C-N 3.31Å; G125-L127 PolarHBondContact O-N 3.32Å; G125-F128 PolarHBondContact O-N 3Å; G125-A129 WeakPolarHBondContact O-CB 3.46Å; G125-A129 PolarHBondContact O-N 3.27Å; G125-P436 VanDerWaalsContact O-CB 3.25Å; G125-P436 WeakPolarHBondContact O-CB 3.44Å
126	V	85.9	Confident	78.8	Confident	57 Å²	57	37.1 Å²	37.1	35%	0.345	20%	0.2	S	C	.	.	H	α-helix	trans	-62	-38.6	176	170.3	0	0	0	0	111.6	V122 I124 A129 S130 F179	V122-V126 HydrophobicContact CG1-CG2 4.37Å; V122-V126 WeakPolarHBondContact O-CB 3.35Å; V122-V126 VanDerWaalsContact O-CG2 3.22Å; V122-V126 WeakPolarHBondContact O-CG2 3.49Å; V122-V126 PolarHBondContact O-N 2.86Å; I124-V126 PolarHBondContact O-N 2.88Å; V126-A129 PolarHBondContact O-N 3.44Å; V126-S130 WeakPolarHBondContact O-CB 3.4Å; V126-S130 PolarHBondContact O-N 2.98Å; V126-F179 HydrophobicContact CG1-CE2 4.05Å
127	L	87.1	Confident	80.8	Confident	0 Å²	0	41.1 Å²	41.1	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-63.6	-44.9	177.4	-175	66.1	0	0	0	111.7	V57 I61 K123 I124 G125 S130 Y175 L178 F179 R182	V57-L127 HydrophobicContact CG1-CD2 3.98Å; V57-L127 HydrophobicContact CG2-CD2 3.88Å; I61-L127 HydrophobicContact CD1-CD2 4.38Å; K123-L127 VanDerWaalsContact O-CB 3.28Å; K123-L127 WeakPolarHBondContact O-CB 3.48Å; K123-L127 PolarHBondContact O-N 2.98Å; I124-L127 WeakPolarHBondContact O-CB 3.5Å; I124-L127 PolarHBondContact O-N 3.33Å; I124-L127 VanDerWaalsContact O-N 3.11Å; G125-L127 VanDerWaalsContact C-N 3.31Å; G125-L127 PolarHBondContact O-N 3.32Å; L127-S130 PolarHBondContact O-N 3.29Å; L127-S130 PolarHBondContact O-OG 3.05Å; L127-Y175 HydrophobicContact CB-CE2 4.4Å; L127-L178 HydrophobicContact CD1-CB 4.04Å; L127-L178 HydrophobicContact CD2-CB 4.4Å; L127-F179 HydrophobicContact CD1-CB 4.23Å; L127-R182 HydrophobicContact CD1-CB 4.16Å; L127-R182 HydrophobicContact CD1-CG 3.76Å; L127-R182 HydrophobicContact CG-CG 4.09Å
128	F	84.8	Confident	82.5	Confident	1 Å²	1	39 Å²	39	0%	0.004	21%	0.205	C	C	.	.	H	α-helix	trans	-64.6	-43.3	175.4	-82.4	-81.3	0	0	0	112.2	I53 V54 V57 I124 G125 S130 P310 P436	I53-F128 HydrophobicContact CG2-CE1 4.4Å; I53-F128 HydrophobicContact CG2-CZ 4.14Å; V54-F128 HydrophobicContact CG2-CE1 3.75Å; V54-F128 HydrophobicContact CG2-CZ 4.13Å; V57-F128 HydrophobicContact CB-CE2 4.34Å; V57-F128 HydrophobicContact CB-CZ 4.4Å; V57-F128 HydrophobicContact CG1-CE2 3.94Å; V57-F128 HydrophobicContact CG1-CZ 4.48Å; I124-F128 HydrophobicContact CG2-CD2 3.74Å; I124-F128 HydrophobicContact CG2-CE2 3.63Å; I124-F128 VanDerWaalsContact O-CD2 3.26Å; I124-F128 WeakPolarHBondContact O-CD2 3.42Å; I124-F128 PolarHBondContact O-N 3.27Å; G125-F128 PolarHBondContact O-N 3Å; F128-S130 VanDerWaalsContact C-N 3.3Å; F128-S130 PolarHBondContact O-N 3.25Å; F128-P310 HydrophobicContact CD2-CB 4.06Å; F128-P310 HydrophobicContact CE2-CB 4.3Å; F128-P436 HydrophobicContact CB-CB 3.9Å; F128-P436 HydrophobicContact CB-CG 3.83Å
129	A	88.9	Confident	84.1	Confident	0 Å²	0	31.7 Å²	31.7	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-67.9	-27.5	179.7	0	0	0	0	0	113.3	G125 V126 K131 A132 I133 A433 P436 I437	G125-A129 WeakPolarHBondContact O-CB 3.46Å; G125-A129 PolarHBondContact O-N 3.27Å; V126-A129 PolarHBondContact O-N 3.44Å; A129-K131 VanDerWaalsContact C-N 3.3Å; A129-K131 PolarHBondContact O-N 2.89Å; A129-A132 PolarHBondContact O-N 3.22Å; A129-A132 VanDerWaalsContact O-N 3.12Å; A129-I133 HydrophobicContact CB-CD1 4.19Å; A129-I133 VanDerWaalsContact O-CG1 3.3Å; A129-I133 WeakPolarHBondContact O-CG1 3.42Å; A129-I133 PolarHBondContact O-N 3.4Å; A129-A433 WeakPolarHBondContact CB-O 3.47Å; A129-P436 HydrophobicContact CB-CB 4.43Å; A129-I437 HydrophobicContact CB-CD1 3.74Å; A129-I437 HydrophobicContact CB-CG1 3.57Å
130	S	91.8	Very high	85	Confident	6 Å²	6	32.2 Å²	32.2	4%	0.042	17%	0.173	C	C	.	.	H	α-helix	trans	-58.5	-36.5	-177.1	71.6	0	0	0	0	114	V126 L127 F128 L134 F179 R182	V126-S130 WeakPolarHBondContact O-CB 3.4Å; V126-S130 PolarHBondContact O-N 2.98Å; L127-S130 PolarHBondContact O-N 3.29Å; L127-S130 PolarHBondContact O-OG 3.05Å; F128-S130 VanDerWaalsContact C-N 3.3Å; F128-S130 PolarHBondContact O-N 3.25Å; S130-L134 PolarHBondContact O-N 2.88Å; S130-F179 VanDerWaalsContact CB-CE2 3.45Å; S130-R182 WeakPolarHBondContact OG-CB 3.28Å
131	K	91.8	Very high	85.5	Confident	9 Å²	9	36.4 Å²	36.4	4%	0.039	20%	0.196	C	C	.	.	H	α-helix	trans	-59.9	-56.4	172.5	-179	-162.1	-173.6	-97.4	0	109.9	D46 Y50 A129 I133 L134 Q135 R182 G186 S189	D46-K131 WeakPolarHBondContact OD1-CE 3.37Å; D46-K131 IonicContact OD1-NZ 2.95Å; D46-K131 PolarHBondContact OD1-NZ 2.97Å; D46-K131 VanDerWaalsContact OD1-NZ 3.15Å; D46-K131 IonicContact OD2-NZ 2.88Å; D46-K131 PolarHBondContact OD2-NZ 2.98Å; Y50-K131 HydrophobicContact CD2-CD 3.52Å; Y50-K131 HydrophobicContact CE2-CD 4.16Å; Y50-K131 HydrophobicContact CG-CD 4.44Å; A129-K131 VanDerWaalsContact C-N 3.3Å; A129-K131 PolarHBondContact O-N 2.89Å; K131-I133 VanDerWaalsContact C-N 3.33Å; K131-I133 PolarHBondContact O-N 2.68Å; K131-L134 PolarHBondContact O-N 2.88Å; K131-Q135 WeakPolarHBondContact O-CB 3.43Å; K131-Q135 PolarHBondContact O-N 3.44Å; K131-R182 WeakPolarHBondContact CA-O 3.37Å; K131-G186 WeakPolarHBondContact O-CA 3.25Å; K131-S189 PolarHBondContact NZ-OG 3.25Å; K131-S189 VanDerWaalsContact NZ-OG 3.16Å
132	A	91.4	Very high	85.7	Confident	3 Å²	3	34.8 Å²	34.8	3%	0.025	19%	0.188	C	C	.	.	H	α-helix	trans	-64.8	-36.4	-173.7	0	0	0	0	0	112.3	A129 Q135 L136 A433	A129-A132 PolarHBondContact O-N 3.22Å; A129-A132 VanDerWaalsContact O-N 3.12Å; A132-Q135 PolarHBondContact O-N 3.47Å; A132-L136 VanDerWaalsContact O-CB 3.23Å; A132-L136 WeakPolarHBondContact O-CB 3.43Å; A132-L136 PolarHBondContact O-N 3.28Å; A132-A433 HydrophobicContact CB-CB 3.96Å
133	I	92.3	Very high	85.4	Confident	71 Å²	71	32.9 Å²	32.9	36%	0.364	18%	0.18	S	C	.	.	H	α-helix	trans	-63.3	-48.3	174.6	-69	166.9	0	0	0	110.5	A129 K131 L136 L137 A433 I437	A129-I133 HydrophobicContact CB-CD1 4.19Å; A129-I133 VanDerWaalsContact O-CG1 3.3Å; A129-I133 WeakPolarHBondContact O-CG1 3.42Å; A129-I133 PolarHBondContact O-N 3.4Å; K131-I133 VanDerWaalsContact C-N 3.33Å; K131-I133 PolarHBondContact O-N 2.68Å; I133-L136 PolarHBondContact O-N 3.46Å; I133-L137 HydrophobicContact CG2-CD1 4.22Å; I133-L137 WeakPolarHBondContact O-CG 3.5Å; I133-L137 PolarHBondContact O-N 2.95Å; I133-L137 VanDerWaalsContact O-N 3.08Å; I133-A433 HydrophobicContact CG1-CB 3.79Å; I133-I437 HydrophobicContact CD1-CD1 4.03Å
134	L	92.8	Very high	84.9	Confident	52 Å²	52	32.1 Å²	32.1	27%	0.272	18%	0.184	S	C	.	.	H	α-helix	trans	-68.1	-39	-179.7	-164	67.4	0	0	0	111.4	S130 K131 L136 L137 V138 S183 L187	S130-L134 PolarHBondContact O-N 2.88Å; K131-L134 PolarHBondContact O-N 2.88Å; L134-L136 PolarHBondContact O-N 3.38Å; L134-L137 PolarHBondContact O-N 2.87Å; L134-V138 HydrophobicContact CG-CG2 4.21Å; L134-V138 WeakPolarHBondContact O-CB 3.35Å; L134-V138 WeakPolarHBondContact O-CG2 3.49Å; L134-V138 PolarHBondContact O-N 3.3Å; L134-S183 WeakPolarHBondContact CD2-O 3.46Å; L134-L187 HydrophobicContact CD2-CB 3.86Å
135	Q	91.4	Very high	84.5	Confident	9 Å²	9	34.7 Å²	34.7	4%	0.042	20%	0.195	C	C	.	.	H	α-helix	trans	-57.6	-47.6	174	-175.7	168.8	-6.9	0	0	111.3	K131 A132 L137 V138 N139 S189 A190 D425 S429	K131-Q135 WeakPolarHBondContact O-CB 3.43Å; K131-Q135 PolarHBondContact O-N 3.44Å; A132-Q135 PolarHBondContact O-N 3.47Å; Q135-L137 VanDerWaalsContact C-N 3.31Å; Q135-L137 PolarHBondContact O-N 3.3Å; Q135-V138 PolarHBondContact O-N 2.82Å; Q135-V138 VanDerWaalsContact O-N 3.16Å; Q135-N139 WeakPolarHBondContact O-CB 3.08Å; Q135-N139 PolarHBondContact O-N 3.48Å; Q135-N139 PolarHBondContact O-OD1 3.12Å; Q135-S189 PolarHBondContact NE2-OG 3.14Å; Q135-S189 PolarHBondContact OE1-OG 2.87Å; Q135-S189 VanDerWaalsContact OE1-OG 3.09Å; Q135-A190 HydrophobicContact CG-CB 4.19Å; Q135-D425 PolarHBondContact NE2-OD1 2.92Å; Q135-D425 VanDerWaalsContact NE2-OD1 3.17Å; Q135-D425 PolarHBondContact NE2-OD2 3.48Å; Q135-S429 WeakPolarHBondContact CG-OG 3.19Å
136	L	89.5	Confident	84	Confident	50 Å²	50	35 Å²	35	26%	0.262	20%	0.196	S	C	.	.	H	α-helix	trans	-58.2	-39.3	175.9	-177.6	62.1	0	0	0	113	A132 I133 L134 P140 I426 V430	A132-L136 VanDerWaalsContact O-CB 3.23Å; A132-L136 WeakPolarHBondContact O-CB 3.43Å; A132-L136 PolarHBondContact O-N 3.28Å; I133-L136 PolarHBondContact O-N 3.46Å; L134-L136 PolarHBondContact O-N 3.38Å; L136-P140 WeakPolarHBondContact O-CD 3.2Å; L136-I426 HydrophobicContact CD1-CB 4.27Å; L136-I426 HydrophobicContact CD1-CG1 4.32Å; L136-I426 HydrophobicContact CD1-CG2 3.71Å; L136-V430 HydrophobicContact CD1-CG2 3.82Å; L136-V430 HydrophobicContact CD2-CG2 3.93Å
137	L	89.6	Confident	83.1	Confident	112 Å²	112	35 Å²	35	59%	0.586	19%	0.194	S	C	*	.	H	α-helix	trans	-72.9	-32.8	178.5	-69.3	174.1	0	0	0	112.7	I133 L134 Q135	I133-L137 HydrophobicContact CG2-CD1 4.22Å; I133-L137 WeakPolarHBondContact O-CG 3.5Å; I133-L137 PolarHBondContact O-N 2.95Å; I133-L137 VanDerWaalsContact O-N 3.08Å; L134-L137 PolarHBondContact O-N 2.87Å; Q135-L137 VanDerWaalsContact C-N 3.31Å; Q135-L137 PolarHBondContact O-N 3.3Å
138	V	88.4	Confident	82.2	Confident	13 Å²	13	44.7 Å²	44.7	8%	0.079	23%	0.231	C	C	.	.	H	α-helix	trans	-85.2	-33.5	-176.1	174.8	0	0	0	0	111.9	L134 Q135 L141 S142 L187 A190 F191	L134-V138 HydrophobicContact CG-CG2 4.21Å; L134-V138 WeakPolarHBondContact O-CB 3.35Å; L134-V138 WeakPolarHBondContact O-CG2 3.49Å; L134-V138 PolarHBondContact O-N 3.3Å; Q135-V138 PolarHBondContact O-N 2.82Å; Q135-V138 VanDerWaalsContact O-N 3.16Å; V138-L141 CarbonylContact O-C 3.36Å; V138-L141 WeakPolarHBondContact O-CA 3.29Å; V138-L141 WeakPolarHBondContact O-CB 3.26Å; V138-L141 PolarHBondContact O-N 2.85Å; V138-S142 PolarHBondContact O-N 3.13Å; V138-L187 HydrophobicContact CB-CD1 4.31Å; V138-L187 HydrophobicContact CG1-CD1 3.86Å; V138-L187 HydrophobicContact CG2-CD1 3.49Å; V138-L187 VanDerWaalsContact CG2-CD1 3.49Å; V138-A190 HydrophobicContact CB-CB 3.76Å; V138-A190 HydrophobicContact CG1-CB 3.52Å; V138-F191 HydrophobicContact CG1-CD2 4.5Å; V138-F191 HydrophobicContact CG1-CE2 4.09Å; V138-F191 HydrophobicContact CG1-CZ 4.13Å
139	N	84.4	Confident	81.3	Confident	0 Å²	0	48.5 Å²	48.5	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-53	-42.4	-176.4	-79.2	-9.1	0	0	0	115.2	Q135 L141 S142 A190 D425 I426	Q135-N139 WeakPolarHBondContact O-CB 3.08Å; Q135-N139 PolarHBondContact O-N 3.48Å; Q135-N139 PolarHBondContact O-OD1 3.12Å; N139-L141 PolarHBondContact O-N 3.16Å; N139-S142 PolarHBondContact O-N 2.87Å; N139-S142 PolarHBondContact O-OG 2.86Å; N139-A190 WeakPolarHBondContact OD1-CA 3.39Å; N139-A190 WeakPolarHBondContact OD1-CB 3.47Å; N139-D425 PolarHBondContact ND2-OD2 3.17Å; N139-D425 PolarHBondContact OD1-OD2 2.93Å; N139-I426 HydrophobicContact CB-CD1 4.37Å; N139-I426 HydrophobicContact CB-CG1 3.88Å
140	P	80.8	Confident	80.5	Confident	62 Å²	62	49.3 Å²	49.3	40%	0.403	26%	0.255	S	S	.	.	H	α-helix	trans	-67.4	-25.8	175	-22.2	34.3	0	0	0	113.5	L136 P144 I426	L136-P140 WeakPolarHBondContact O-CD 3.2Å; P140-P144 WeakPolarHBondContact O-CD 3.38Å; P140-I426 HydrophobicContact CG-CD1 4.39Å
141	L	78.6	Confident	79.8	Confident	122 Å²	122	51.2 Å²	51.2	64%	0.639	26%	0.262	S	S	*	.	H	α-helix	trans	-86.5	-27.4	-179.5	-59.6	174.2	0	0	0	112.5	V138 N139 G143 F145	V138-L141 CarbonylContact O-C 3.36Å; V138-L141 WeakPolarHBondContact O-CA 3.29Å; V138-L141 WeakPolarHBondContact O-CB 3.26Å; V138-L141 PolarHBondContact O-N 2.85Å; N139-L141 PolarHBondContact O-N 3.16Å; L141-G143 VanDerWaalsContact C-N 3.34Å; L141-G143 PolarHBondContact O-N 3.06Å; L141-F145 WeakPolarHBondContact O-CB 3.18Å; L141-F145 PolarHBondContact O-N 3.47Å
142	S	74.9	Confident	79.3	Confident	0 Å²	0	51.6 Å²	51.6	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-66.1	-35.9	-179.4	65	0	0	0	0	112.1	V138 N139 F145 I146 T194	V138-S142 PolarHBondContact O-N 3.13Å; N139-S142 PolarHBondContact O-N 2.87Å; N139-S142 PolarHBondContact O-OG 2.86Å; S142-F145 WeakPolarHBondContact O-CB 3.41Å; S142-F145 PolarHBondContact O-N 2.84Å; S142-I146 WeakPolarHBondContact O-CB 3.43Å; S142-I146 WeakPolarHBondContact O-CD1 3.35Å; S142-I146 WeakPolarHBondContact O-CG1 3.46Å; S142-I146 PolarHBondContact O-N 3.41Å; S142-T194 PolarHBondContact OG-OG1 3.34Å
143	G	68.4	Low	79	Confident	20 Å²	20	52.7 Å²	52.7	21%	0.206	27%	0.271	C	S	.	.	H	α-helix	trans	-54.3	-63.2	177.7	0	0	0	0	0	113.6	L141 F145 I146 D147	L141-G143 VanDerWaalsContact C-N 3.34Å; L141-G143 PolarHBondContact O-N 3.06Å; G143-F145 PolarHBondContact O-N 3.13Å; G143-F145 VanDerWaalsContact O-N 3.15Å; G143-I146 PolarHBondContact O-N 3.15Å; G143-I146 VanDerWaalsContact O-N 3.13Å; G143-D147 PolarHBondContact O-N 3.29Å
144	P	69.7	Low	78.8	Confident	71 Å²	71	49.3 Å²	49.3	46%	0.461	25%	0.253	S	S	.	.	H	α-helix	trans	-59.8	-27.1	176.9	-24.9	34	0	0	0	114.2	P140 R148	P140-P144 WeakPolarHBondContact O-CD 3.38Å; P144-R148 WeakPolarHBondContact O-CG 3.24Å; P144-R148 PolarHBondContact O-N 2.63Å
145	F	72.3	Confident	78.6	Confident	67 Å²	67	46.9 Å²	46.9	29%	0.294	24%	0.24	S	C	.	.	H	α-helix	trans	-72	-42.7	176.9	-171.5	-99.6	0	0	0	111.7	L141 S142 G143 R148 M149 P154 I157 F191	L141-F145 WeakPolarHBondContact O-CB 3.18Å; L141-F145 PolarHBondContact O-N 3.47Å; S142-F145 WeakPolarHBondContact O-CB 3.41Å; S142-F145 PolarHBondContact O-N 2.84Å; G143-F145 PolarHBondContact O-N 3.13Å; G143-F145 VanDerWaalsContact O-N 3.15Å; F145-R148 PolarHBondContact O-N 3.2Å; F145-M149 HydrophobicContact CD1-SD 4.47Å; F145-M149 HydrophobicContact CD2-SD 4.46Å; F145-M149 HydrophobicContact CE1-SD 3.74Å; F145-M149 HydrophobicContact CE2-CE 3.79Å; F145-M149 HydrophobicContact CE2-SD 3.73Å; F145-M149 HydrophobicContact CZ-CE 3.9Å; F145-M149 HydrophobicContact CZ-SD 3.32Å; F145-M149 WeakPolarHBondContact CZ-SD 3.43Å; F145-M149 WeakPolarHBondContact O-CB 3.35Å; F145-M149 PolarHBondContact O-N 3.03Å; F145-P154 HydrophobicContact CD1-CB 4.14Å; F145-P154 HydrophobicContact CD1-CG 3.91Å; F145-P154 HydrophobicContact CE1-CB 4.19Å; F145-P154 HydrophobicContact CE1-CG 3.99Å; F145-I157 HydrophobicContact CE1-CD1 4.14Å; F145-I157 HydrophobicContact CZ-CD1 4.27Å; F145-F191 HydrophobicContact CB-CE1 4.48Å; F145-F191 HydrophobicContact CD1-CD1 4.3Å; F145-F191 AromaticContact CD1-CE1 3.65Å; F145-F191 HydrophobicContact CD1-CE1 3.65Å; F145-F191 HydrophobicContact CD1-CZ 4.38Å; F145-F191 HydrophobicContact CE1-CE1 4.14Å; F145-F191 HydrophobicContact CG-CE1 4.22Å
146	I	70.2	Confident	78.6	Confident	10 Å²	10	47.9 Å²	47.9	5%	0.051	25%	0.246	C	C	.	.	H	α-helix	trans	-67.5	-35.8	173.6	-67.9	161.9	0	0	0	111.3	S142 G143 R148 M149 Y151 P154 T194 S195	S142-I146 WeakPolarHBondContact O-CB 3.43Å; S142-I146 WeakPolarHBondContact O-CD1 3.35Å; S142-I146 WeakPolarHBondContact O-CG1 3.46Å; S142-I146 PolarHBondContact O-N 3.41Å; G143-I146 PolarHBondContact O-N 3.15Å; G143-I146 VanDerWaalsContact O-N 3.13Å; I146-R148 PolarHBondContact O-N 3.48Å; I146-M149 CarbonylContact C-O 3.44Å; I146-M149 CarbonylContact O-C 3.56Å; I146-M149 PolarHBondContact O-N 3.37Å; I146-Y151 HydrophobicContact CG2-CD1 3.28Å; I146-Y151 HydrophobicContact CG2-CE1 3.57Å; I146-Y151 HydrophobicContact CG2-CG 4.36Å; I146-P154 HydrophobicContact CG1-CB 3.89Å; I146-P154 HydrophobicContact CG1-CG 3.87Å; I146-T194 VanDerWaalsContact CD1-OG1 3.24Å; I146-T194 WeakPolarHBondContact CD1-OG1 3.31Å; I146-S195 VanDerWaalsContact CD1-OG 3.26Å; I146-S195 WeakPolarHBondContact CD1-OG 3.43Å; I146-S195 WeakPolarHBondContact CG1-OG 3.36Å
147	D	66.9	Low	78.7	Confident	57 Å²	57	48.7 Å²	48.7	31%	0.305	25%	0.25	S	C	.	.	H	α-helix	trans	-64.3	-34.2	177.4	-66.3	-23.9	0	0	0	111.3	G143	G143-D147 PolarHBondContact O-N 3.29Å
148	R	66.7	Low	78.9	Confident	204 Å²	204	43.3 Å²	43.3	77%	0.77	22%	0.222	S	C	*	.	H	α-helix	trans	-84.5	-29.2	178	-71.3	-179.9	178.4	-179.3	1.3	114.1	P144 F145 I146 A274	P144-R148 WeakPolarHBondContact O-CG 3.24Å; P144-R148 PolarHBondContact O-N 2.63Å; F145-R148 PolarHBondContact O-N 3.2Å; I146-R148 PolarHBondContact O-N 3.48Å; R148-A274 WeakPolarHBondContact O-CB 3.37Å
149	M	66.6	Low	79.1	Confident	81 Å²	81	42.7 Å²	42.7	40%	0.399	22%	0.218	S	C	.	.	S	Bend	trans	-122.2	118.1	-177.1	-65.3	-175	-178.7	0	0	108.6	F145 I146 Y151 V153 P154	F145-M149 HydrophobicContact CD1-SD 4.47Å; F145-M149 HydrophobicContact CD2-SD 4.46Å; F145-M149 HydrophobicContact CE1-SD 3.74Å; F145-M149 HydrophobicContact CE2-CE 3.79Å; F145-M149 HydrophobicContact CE2-SD 3.73Å; F145-M149 HydrophobicContact CZ-CE 3.9Å; F145-M149 HydrophobicContact CZ-SD 3.32Å; F145-M149 WeakPolarHBondContact CZ-SD 3.43Å; F145-M149 WeakPolarHBondContact O-CB 3.35Å; F145-M149 PolarHBondContact O-N 3.03Å; I146-M149 CarbonylContact C-O 3.44Å; I146-M149 CarbonylContact O-C 3.56Å; I146-M149 PolarHBondContact O-N 3.37Å; M149-Y151 PolarHBondContact O-N 3.42Å; M149-V153 HydrophobicContact SD-CG1 4.36Å; M149-P154 HydrophobicContact CB-CG 4.19Å
150	S	72.3	Confident	79.6	Confident	17 Å²	17	44.3 Å²	44.3	12%	0.119	23%	0.234	C	C	.	.			trans	-39.3	137.5	178.6	-43.9	0	0	0	0	112.6	D152 V153 P154 A270	S150-D152 PolarHBondContact O-N 3.24Å; S150-V153 PolarHBondContact O-N 3.22Å; S150-P154 WeakPolarHBondContact O-CD 3.47Å; S150-A270 WeakPolarHBondContact OG-CA 3.43Å; S150-A270 WeakPolarHBondContact OG-CB 3.21Å; S150-A270 PolarHBondContact OG-O 3.4Å
151	Y	76.3	Confident	80.3	Confident	45 Å²	45	42.6 Å²	42.6	18%	0.176	22%	0.223	C	C	.	.	T	Hydrogen-bonded Turn	trans	-43.8	-29.4	-173.3	-47.3	-75.3	0	0	0	115.3	I146 M149 L155 A198 D202	I146-Y151 HydrophobicContact CG2-CD1 3.28Å; I146-Y151 HydrophobicContact CG2-CE1 3.57Å; I146-Y151 HydrophobicContact CG2-CG 4.36Å; M149-Y151 PolarHBondContact O-N 3.42Å; Y151-L155 WeakPolarHBondContact O-CB 3.38Å; Y151-L155 PolarHBondContact O-N 3.35Å; Y151-A198 HydrophobicContact CD1-CB 3.63Å; Y151-A198 HydrophobicContact CE1-CB 3.75Å; Y151-D202 HydrophobicContact CD2-CB 4.45Å; Y151-D202 HydrophobicContact CE2-CB 3.98Å
152	D	82.3	Confident	81	Confident	17 Å²	17	36.8 Å²	36.8	9%	0.091	19%	0.192	C	C	.	.	H	α-helix	trans	-65.5	-36	179.9	-47	-46.4	0	0	0	113.6	S150 L156 M199 A263 P265	S150-D152 PolarHBondContact O-N 3.24Å; D152-L156 WeakPolarHBondContact O-CB 3.44Å; D152-L156 PolarHBondContact O-N 3.36Å; D152-L156 VanDerWaalsContact O-N 3.14Å; D152-M199 HydrophobicContact CB-CE 4.28Å; D152-M199 WeakPolarHBondContact OD1-CE 3.17Å; D152-A263 HydrophobicContact CB-CB 3.93Å; D152-P265 HydrophobicContact CB-CB 3.89Å
153	V	85.6	Confident	82	Confident	27 Å²	27	40 Å²	40	16%	0.164	21%	0.206	C	C	.	.	H	α-helix	trans	-73.6	-50.8	-177	172.4	0	0	0	0	111.2	M149 S150 L155 L156 I157 P265	M149-V153 HydrophobicContact SD-CG1 4.36Å; S150-V153 PolarHBondContact O-N 3.22Å; V153-L155 VanDerWaalsContact C-N 3.32Å; V153-L155 PolarHBondContact O-N 2.99Å; V153-L156 PolarHBondContact O-N 3.44Å; V153-I157 HydrophobicContact CG1-CD1 3.94Å; V153-I157 WeakPolarHBondContact O-CG1 3.41Å; V153-I157 PolarHBondContact O-N 3.44Å; V153-P265 HydrophobicContact CG2-CB 3.72Å; V153-P265 WeakPolarHBondContact CG2-O 3.13Å
154	P	87.4	Confident	83.3	Confident	0 Å²	0	41.3 Å²	41.3	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-65.5	-34	178.2	-21.2	35.2	0	0	0	112.4	F145 I146 M149 S150 L156 I157 G158 F191 S195	F145-P154 HydrophobicContact CD1-CB 4.14Å; F145-P154 HydrophobicContact CD1-CG 3.91Å; F145-P154 HydrophobicContact CE1-CB 4.19Å; F145-P154 HydrophobicContact CE1-CG 3.99Å; I146-P154 HydrophobicContact CG1-CB 3.89Å; I146-P154 HydrophobicContact CG1-CG 3.87Å; M149-P154 HydrophobicContact CB-CG 4.19Å; S150-P154 WeakPolarHBondContact O-CD 3.47Å; P154-L156 PolarHBondContact O-N 3.18Å; P154-I157 PolarHBondContact O-N 3.25Å; P154-G158 PolarHBondContact O-N 3.14Å; P154-F191 HydrophobicContact CB-CD1 4.2Å; P154-S195 WeakPolarHBondContact CB-OG 3.48Å
155	L	89.1	Confident	84.5	Confident	0 Å²	0	38 Å²	38	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-60.9	-42.9	172.2	-178.3	60.2	0	0	0	112	I38 V39 A42 Y151 V153 G158 L159 A192 M199 L259	I38-L155 HydrophobicContact CG2-CD2 4.47Å; V39-L155 HydrophobicContact CG2-CD2 4.12Å; A42-L155 HydrophobicContact CB-CD1 4.36Å; Y151-L155 WeakPolarHBondContact O-CB 3.38Å; Y151-L155 PolarHBondContact O-N 3.35Å; V153-L155 VanDerWaalsContact C-N 3.32Å; V153-L155 PolarHBondContact O-N 2.99Å; L155-G158 PolarHBondContact O-N 3.15Å; L155-L159 HydrophobicContact CD1-CD1 4.43Å; L155-L159 HydrophobicContact CG-CD1 4.26Å; L155-L159 PolarHBondContact O-N 3.19Å; L155-A192 HydrophobicContact CD1-CB 4.16Å; L155-M199 HydrophobicContact CB-CE 4.34Å; L155-M199 HydrophobicContact CD2-CE 3.53Å; L155-M199 HydrophobicContact CD2-SD 4.12Å; L155-L259 HydrophobicContact CB-CD2 4.04Å; L155-L259 HydrophobicContact CD2-CD1 4.01Å; L155-L259 HydrophobicContact CD2-CD2 3.81Å; L155-L259 HydrophobicContact CG-CD2 3.68Å
156	L	91.3	Very high	85.5	Confident	30 Å²	30	34.8 Å²	34.8	16%	0.157	18%	0.18	C	C	.	.	H	α-helix	trans	-64.9	-40.8	176.2	-179.2	66.8	0	0	0	112.3	D152 V153 P154 G158 L159 G160 A256 L259 L260 P265	D152-L156 WeakPolarHBondContact O-CB 3.44Å; D152-L156 PolarHBondContact O-N 3.36Å; D152-L156 VanDerWaalsContact O-N 3.14Å; V153-L156 PolarHBondContact O-N 3.44Å; P154-L156 PolarHBondContact O-N 3.18Å; L156-G158 VanDerWaalsContact C-N 3.33Å; L156-L159 PolarHBondContact O-N 3.46Å; L156-G160 PolarHBondContact O-N 2.95Å; L156-A256 HydrophobicContact CD1-CB 4.12Å; L156-L259 HydrophobicContact CB-CD2 3.9Å; L156-L259 HydrophobicContact CD1-CD2 4.34Å; L156-L260 HydrophobicContact CD1-CD1 4.09Å; L156-L260 HydrophobicContact CD1-CD2 4.31Å; L156-L260 HydrophobicContact CD1-CG 3.77Å; L156-L260 HydrophobicContact CD2-CD1 4.41Å; L156-L260 HydrophobicContact CD2-CD2 3.47Å; L156-L260 VanDerWaalsContact CD2-CD2 3.47Å; L156-L260 HydrophobicContact CD2-CG 3.9Å; L156-P265 HydrophobicContact CD2-CG 4.08Å
157	I	91.4	Very high	86.6	Confident	67 Å²	67	36.3 Å²	36.3	34%	0.344	19%	0.189	S	C	.	.	H	α-helix	trans	-60.6	-46.8	174.3	-67.7	167.3	0	0	0	109.4	F145 V153 P154 G160 V161 F191	F145-I157 HydrophobicContact CE1-CD1 4.14Å; F145-I157 HydrophobicContact CZ-CD1 4.27Å; V153-I157 HydrophobicContact CG1-CD1 3.94Å; V153-I157 WeakPolarHBondContact O-CG1 3.41Å; V153-I157 PolarHBondContact O-N 3.44Å; P154-I157 PolarHBondContact O-N 3.25Å; I157-G160 PolarHBondContact O-N 3.16Å; I157-V161 HydrophobicContact CG2-CG2 4.18Å; I157-V161 WeakPolarHBondContact O-CB 3.22Å; I157-V161 WeakPolarHBondContact O-CG2 3.39Å; I157-V161 PolarHBondContact O-N 2.89Å; I157-F191 HydrophobicContact CG2-CD2 4.49Å
158	G	92.3	Very high	87.8	Confident	0 Å²	0	36.8 Å²	36.8	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-55.9	-52.5	177.1	0	0	0	0	0	112.5	P154 L155 L156 G160 V161 M162 G188	P154-G158 PolarHBondContact O-N 3.14Å; L155-G158 PolarHBondContact O-N 3.15Å; L156-G158 VanDerWaalsContact C-N 3.33Å; G158-G160 PolarHBondContact O-N 2.87Å; G158-V161 PolarHBondContact O-N 3.13Å; G158-M162 WeakPolarHBondContact O-CB 3.27Å; G158-M162 WeakPolarHBondContact O-CG 3.19Å; G158-M162 PolarHBondContact O-N 3.02Å; G158-G188 VanDerWaalsContact CA-O 3.29Å; G158-G188 WeakPolarHBondContact CA-O 3.35Å
159	L	93.4	Very high	88.9	Confident	0 Å²	0	27 Å²	27	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-60.7	-42.6	176.6	-78.1	164.5	0	0	0	112.8	A42 L155 L156 M162 F163 S252 D255 A256 L259	A42-L159 HydrophobicContact CB-CD2 3.87Å; A42-L159 HydrophobicContact CB-CG 4.36Å; L155-L159 HydrophobicContact CD1-CD1 4.43Å; L155-L159 HydrophobicContact CG-CD1 4.26Å; L155-L159 PolarHBondContact O-N 3.19Å; L156-L159 PolarHBondContact O-N 3.46Å; L159-M162 HydrophobicContact CD2-CE 3.81Å; L159-M162 HydrophobicContact CG-CE 4.22Å; L159-M162 PolarHBondContact O-N 3.45Å; L159-F163 WeakPolarHBondContact O-CB 3.27Å; L159-F163 PolarHBondContact O-N 3.14Å; L159-S252 PolarHBondContact O-OG 3.25Å; L159-D255 HydrophobicContact CD2-CB 4.34Å; L159-D255 WeakPolarHBondContact CD2-OD2 3.28Å; L159-A256 HydrophobicContact CB-CB 4Å; L159-L259 HydrophobicContact CD1-CD2 3.94Å
160	G	95.1	Very high	90	Very high	33 Å²	33	23.2 Å²	23.2	34%	0.34	14%	0.135	S	C	.	.	H	α-helix	trans	-64.5	-39.7	177.3	0	0	0	0	0	112.9	L156 I157 G158 F163 A164	L156-G160 PolarHBondContact O-N 2.95Å; I157-G160 PolarHBondContact O-N 3.16Å; G158-G160 PolarHBondContact O-N 2.87Å; G160-F163 PolarHBondContact O-N 3.08Å; G160-A164 WeakPolarHBondContact O-CB 3.45Å; G160-A164 PolarHBondContact O-N 2.87Å
161	V	95.3	Very high	90.8	Very high	27 Å²	27	27.6 Å²	27.6	16%	0.164	15%	0.152	C	C	.	.	H	α-helix	trans	-68.3	-41.8	175.7	171.3	0	0	0	0	110.9	I157 G158 A164 S165 L184 L187	I157-V161 HydrophobicContact CG2-CG2 4.18Å; I157-V161 WeakPolarHBondContact O-CB 3.22Å; I157-V161 WeakPolarHBondContact O-CG2 3.39Å; I157-V161 PolarHBondContact O-N 2.89Å; G158-V161 PolarHBondContact O-N 3.13Å; V161-A164 PolarHBondContact O-N 3.33Å; V161-S165 VanDerWaalsContact O-CB 3.27Å; V161-S165 WeakPolarHBondContact O-CB 3.34Å; V161-S165 PolarHBondContact O-N 2.96Å; V161-S165 PolarHBondContact O-OG 3.3Å; V161-L184 HydrophobicContact CG1-CD1 3.6Å; V161-L184 HydrophobicContact CG1-CG 3.65Å; V161-L184 WeakPolarHBondContact CG1-O 3.42Å; V161-L187 HydrophobicContact CG1-CB 4.35Å; V161-L187 HydrophobicContact CG1-CD2 4.36Å; V161-L187 HydrophobicContact CG1-CG 4.45Å
162	M	93.3	Very high	91.3	Very high	0 Å²	0	25.5 Å²	25.5	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-61.7	-42.9	173.3	-74.7	-169.1	-67.2	0	0	111.9	D46 G158 L159 S165 T166 A192	D46-M162 HydrophobicContact CB-SD 4.04Å; G158-M162 WeakPolarHBondContact O-CB 3.27Å; G158-M162 WeakPolarHBondContact O-CG 3.19Å; G158-M162 PolarHBondContact O-N 3.02Å; L159-M162 HydrophobicContact CD2-CE 3.81Å; L159-M162 HydrophobicContact CG-CE 4.22Å; L159-M162 PolarHBondContact O-N 3.45Å; M162-S165 WeakPolarHBondContact CA-OG 3.21Å; M162-S165 PolarHBondContact O-OG 2.85Å; M162-T166 VanDerWaalsContact O-CB 3.29Å; M162-T166 WeakPolarHBondContact O-CB 3.33Å; M162-T166 PolarHBondContact O-N 3.25Å; M162-T166 PolarHBondContact O-OG1 3.33Å; M162-A192 HydrophobicContact CE-CB 3.53Å; M162-A192 HydrophobicContact SD-CB 4.47Å
163	F	95.6	Very high	91.3	Very high	67 Å²	67	31.2 Å²	31.2	29%	0.294	17%	0.17	S	C	.	.	H	α-helix	trans	-59.3	-54.6	174	169.2	-109.7	0	0	0	111.8	L159 G160 S165 T166 V167 A249 F253	L159-F163 WeakPolarHBondContact O-CB 3.27Å; L159-F163 PolarHBondContact O-N 3.14Å; G160-F163 PolarHBondContact O-N 3.08Å; F163-S165 VanDerWaalsContact C-N 3.34Å; F163-S165 PolarHBondContact O-N 2.83Å; F163-T166 PolarHBondContact O-N 3.09Å; F163-V167 HydrophobicContact CD2-CG2 4.1Å; F163-V167 HydrophobicContact CE1-CG2 4.49Å; F163-V167 HydrophobicContact CE2-CG2 3.67Å; F163-V167 HydrophobicContact CZ-CG2 3.9Å; F163-V167 WeakPolarHBondContact O-CG2 3.37Å; F163-V167 PolarHBondContact O-N 3.26Å; F163-A249 HydrophobicContact CD2-CB 4Å; F163-A249 VanDerWaalsContact CD2-O 3.22Å; F163-A249 WeakPolarHBondContact CD2-O 3.12Å; F163-A249 HydrophobicContact CE2-CB 4.11Å; F163-F253 HydrophobicContact CD2-CB 3.79Å; F163-F253 HydrophobicContact CE1-CD2 4.24Å; F163-F253 HydrophobicContact CE2-CB 3.78Å; F163-F253 HydrophobicContact CE2-CD2 4.29Å; F163-F253 HydrophobicContact CE2-CG 4.33Å; F163-F253 HydrophobicContact CG-CB 4.42Å; F163-F253 HydrophobicContact CZ-CB 4.43Å; F163-F253 HydrophobicContact CZ-CD2 4.1Å
164	A	95.9	Very high	91.3	Very high	48 Å²	48	34.8 Å²	34.8	40%	0.397	19%	0.188	S	C	.	.	H	α-helix	trans	-60.9	-43.2	-177.2	0	0	0	0	0	112.1	G160 V161 V167 M168	G160-A164 WeakPolarHBondContact O-CB 3.45Å; G160-A164 PolarHBondContact O-N 2.87Å; V161-A164 PolarHBondContact O-N 3.33Å; A164-V167 PolarHBondContact O-N 3.48Å; A164-M168 WeakPolarHBondContact O-CB 3.42Å; A164-M168 PolarHBondContact O-N 3.27Å
165	S	95.1	Very high	91.2	Very high	0 Å²	0	38.1 Å²	38.1	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-67.4	-36.2	177.5	57.5	0	0	0	0	113	V161 M162 F163 M168 F169 A181 Q185	V161-S165 VanDerWaalsContact O-CB 3.27Å; V161-S165 WeakPolarHBondContact O-CB 3.34Å; V161-S165 PolarHBondContact O-N 2.96Å; V161-S165 PolarHBondContact O-OG 3.3Å; M162-S165 WeakPolarHBondContact CA-OG 3.21Å; M162-S165 PolarHBondContact O-OG 2.85Å; F163-S165 VanDerWaalsContact C-N 3.34Å; F163-S165 PolarHBondContact O-N 2.83Å; S165-M168 PolarHBondContact O-N 2.95Å; S165-F169 WeakPolarHBondContact O-CB 3.48Å; S165-F169 PolarHBondContact O-N 2.91Å; S165-A181 WeakPolarHBondContact CB-O 3.3Å; S165-Q185 WeakPolarHBondContact OG-CG 3.46Å
166	T	92.6	Very high	91.1	Very high	0 Å²	0	41.5 Å²	41.5	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-68.5	-41.3	176.3	-56.2	0	0	0	0	111.7	L49 M162 F163 F169 A170 F245 L248 A249	L49-T166 WeakPolarHBondContact CD1-OG1 3.29Å; L49-T166 HydrophobicContact CD2-CG2 3.51Å; L49-T166 WeakPolarHBondContact CD2-OG1 3.38Å; M162-T166 VanDerWaalsContact O-CB 3.29Å; M162-T166 WeakPolarHBondContact O-CB 3.33Å; M162-T166 PolarHBondContact O-N 3.25Å; M162-T166 PolarHBondContact O-OG1 3.33Å; F163-T166 PolarHBondContact O-N 3.09Å; T166-F169 WeakPolarHBondContact O-CB 3.45Å; T166-F169 PolarHBondContact O-N 3.43Å; T166-A170 PolarHBondContact O-N 3.15Å; T166-F245 HydrophobicContact CG2-CB 4.11Å; T166-F245 HydrophobicContact CG2-CD1 4.5Å; T166-F245 WeakPolarHBondContact CG2-O 3.37Å; T166-L248 HydrophobicContact CG2-CB 4.41Å; T166-A249 HydrophobicContact CG2-CB 3.88Å
167	V	94.2	Very high	91	Very high	43 Å²	43	42 Å²	42	26%	0.261	23%	0.234	S	C	.	.	H	α-helix	trans	-62.8	-45.6	173	174	0	0	0	0	110.3	F163 A164 F169 A170 F171 A249	F163-V167 HydrophobicContact CD2-CG2 4.1Å; F163-V167 HydrophobicContact CE1-CG2 4.49Å; F163-V167 HydrophobicContact CE2-CG2 3.67Å; F163-V167 HydrophobicContact CZ-CG2 3.9Å; F163-V167 WeakPolarHBondContact O-CG2 3.37Å; F163-V167 PolarHBondContact O-N 3.26Å; A164-V167 PolarHBondContact O-N 3.48Å; V167-F169 VanDerWaalsContact C-N 3.26Å; V167-F169 PolarHBondContact O-N 2.67Å; V167-A170 WeakPolarHBondContact O-CB 2.96Å; V167-A170 PolarHBondContact O-N 3.01Å; V167-A170 VanDerWaalsContact O-N 3.15Å; V167-F171 HydrophobicContact CG1-CD2 4.03Å; V167-F171 HydrophobicContact CG1-CE2 4.08Å; V167-F171 VanDerWaalsContact O-CD2 3.3Å; V167-F171 WeakPolarHBondContact O-CD2 3.48Å; V167-F171 PolarHBondContact O-N 3.04Å; V167-A249 HydrophobicContact CG2-CB 3.8Å
168	M	92.7	Very high	90.8	Very high	66 Å²	66	38.9 Å²	38.9	33%	0.325	22%	0.218	S	C	.	.	H	α-helix	trans	-57.5	-40.3	175.4	-174.6	-179	176.8	0	0	111.6	A164 S165 F171 A172 T177 A180 A181	A164-M168 WeakPolarHBondContact O-CB 3.42Å; A164-M168 PolarHBondContact O-N 3.27Å; S165-M168 PolarHBondContact O-N 2.95Å; M168-F171 PolarHBondContact O-N 2.92Å; M168-A172 WeakPolarHBondContact O-CB 3.34Å; M168-A172 PolarHBondContact O-N 2.97Å; M168-A172 VanDerWaalsContact O-N 3.1Å; M168-T177 HydrophobicContact CE-CG2 3.58Å; M168-T177 HydrophobicContact CG-CG2 3.95Å; M168-A180 HydrophobicContact CE-CB 3.66Å; M168-A181 HydrophobicContact CB-CB 4.19Å; M168-A181 HydrophobicContact CG-CB 4.01Å; M168-A181 HydrophobicContact SD-CB 4.06Å
169	F	89.3	Confident	90.7	Very high	0 Å²	0	42.8 Å²	42.8	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-64.1	-42.4	176.3	-159.5	-83.2	0	0	0	112.1	I53 V57 S165 T166 V167 F171 A172 L178 A181 R182 F245	I53-F169 HydrophobicContact CD1-CD1 4.37Å; I53-F169 HydrophobicContact CD1-CD2 4.35Å; I53-F169 HydrophobicContact CD1-CE1 3.94Å; I53-F169 HydrophobicContact CD1-CE2 3.91Å; I53-F169 HydrophobicContact CD1-CZ 3.69Å; I53-F169 HydrophobicContact CG1-CE1 4.16Å; I53-F169 HydrophobicContact CG1-CZ 4.13Å; I53-F169 HydrophobicContact CG2-CE1 4.41Å; I53-F169 HydrophobicContact CG2-CZ 3.83Å; V57-F169 HydrophobicContact CG2-CZ 3.89Å; S165-F169 WeakPolarHBondContact O-CB 3.48Å; S165-F169 PolarHBondContact O-N 2.91Å; T166-F169 WeakPolarHBondContact O-CB 3.45Å; T166-F169 PolarHBondContact O-N 3.43Å; V167-F169 VanDerWaalsContact C-N 3.26Å; V167-F169 PolarHBondContact O-N 2.67Å; F169-F171 PolarHBondContact O-N 3.16Å; F169-A172 WeakPolarHBondContact O-CB 3.3Å; F169-A172 PolarHBondContact O-N 2.84Å; F169-L178 HydrophobicContact CD1-CD2 4.3Å; F169-L178 HydrophobicContact CD2-CD2 3.78Å; F169-L178 HydrophobicContact CE1-CD2 3.99Å; F169-L178 HydrophobicContact CE2-CD2 3.44Å; F169-L178 VanDerWaalsContact CE2-CD2 3.44Å; F169-L178 HydrophobicContact CG-CD2 4.2Å; F169-L178 HydrophobicContact CZ-CD2 3.55Å; F169-A181 HydrophobicContact CB-CB 4.13Å; F169-A181 HydrophobicContact CD2-CB 4.01Å; F169-R182 HydrophobicContact CD2-CG 4.28Å; F169-R182 HydrophobicContact CE2-CG 3.79Å; F169-F245 AromaticContact CD1-CD1 3.78Å; F169-F245 HydrophobicContact CD1-CD1 3.78Å; F169-F245 AromaticContact CD1-CD2 3.98Å; F169-F245 HydrophobicContact CD1-CD2 3.98Å; F169-F245 AromaticContact CD1-CE1 3.55Å; F169-F245 HydrophobicContact CD1-CE1 3.55Å; F169-F245 AromaticContact CD1-CE2 3.74Å; F169-F245 HydrophobicContact CD1-CE2 3.74Å; F169-F245 HydrophobicContact CD1-CG 4Å; F169-F245 AromaticContact CD1-CZ 3.54Å; F169-F245 HydrophobicContact CD1-CZ 3.54Å; F169-F245 HydrophobicContact CE1-CD1 4.34Å; F169-F245 HydrophobicContact CE1-CD2 4.41Å; F169-F245 AromaticContact CE1-CE1 3.65Å; F169-F245 HydrophobicContact CE1-CE1 3.65Å; F169-F245 AromaticContact CE1-CE2 3.71Å; F169-F245 HydrophobicContact CE1-CE2 3.71Å; F169-F245 AromaticContact CE1-CZ 3.29Å; F169-F245 HydrophobicContact CE1-CZ 3.29Å; F169-F245 HydrophobicContact CZ-CZ 4.41Å
170	A	89.6	Confident	90.7	Very high	1 Å²	1	44.8 Å²	44.8	1%	0.008	25%	0.251	C	S	.	.	H	α-helix	trans	-61.6	-29.4	179.9	0	0	0	0	0	113.7	T166 V167 R242 F245 L246	T166-A170 PolarHBondContact O-N 3.15Å; V167-A170 WeakPolarHBondContact O-CB 2.96Å; V167-A170 PolarHBondContact O-N 3.01Å; V167-A170 VanDerWaalsContact O-N 3.15Å; A170-R242 WeakPolarHBondContact O-CG 3.26Å; A170-F245 HydrophobicContact CB-CB 3.71Å; A170-L246 HydrophobicContact CB-CD2 4.22Å; A170-L246 HydrophobicContact CB-CG 4.28Å
171	F	88.9	Confident	90.6	Very high	109 Å²	109	43.2 Å²	43.2	48%	0.478	24%	0.235	S	C	.	.	T	Hydrogen-bonded Turn	trans	-108	10.7	-179.7	-64.3	-75	0	0	0	113.4	V167 M168 F169 E173 L246	V167-F171 HydrophobicContact CG1-CD2 4.03Å; V167-F171 HydrophobicContact CG1-CE2 4.08Å; V167-F171 VanDerWaalsContact O-CD2 3.3Å; V167-F171 WeakPolarHBondContact O-CD2 3.48Å; V167-F171 PolarHBondContact O-N 3.04Å; M168-F171 PolarHBondContact O-N 2.92Å; F169-F171 PolarHBondContact O-N 3.16Å; F171-E173 PolarHBondContact O-N 3.5Å; F171-L246 HydrophobicContact CE2-CD2 4.15Å; F171-L246 HydrophobicContact CZ-CD2 4.4Å
172	A	86.6	Confident	90.4	Very high	0 Å²	0	41.9 Å²	41.9	0%	0	23%	0.227	C	C	.	.			trans	-71.9	116.7	-176.1	0	0	0	0	0	111.6	Y60 M64 M168 F169 T177 L178	Y60-A172 WeakPolarHBondContact CE1-O 3.4Å; Y60-A172 VanDerWaalsContact CZ-O 3.32Å; Y60-A172 PolarHBondContact OH-O 3.11Å; M64-A172 VanDerWaalsContact CE-O 3.25Å; M64-A172 WeakPolarHBondContact CE-O 3.47Å; M168-A172 WeakPolarHBondContact O-CB 3.34Å; M168-A172 PolarHBondContact O-N 2.97Å; M168-A172 VanDerWaalsContact O-N 3.1Å; F169-A172 WeakPolarHBondContact O-CB 3.3Å; F169-A172 PolarHBondContact O-N 2.84Å; A172-T177 HydrophobicContact CB-CG2 3.77Å; A172-L178 HydrophobicContact CB-CD2 3.61Å; A172-L178 HydrophobicContact CB-CG 3.8Å
173	E	83.7	Confident	90.4	Very high	137 Å²	137	42.9 Å²	42.9	64%	0.64	23%	0.234	S	C	*	.			trans	-99.2	-11.2	178.3	-63.3	-174.5	167.3	0	0	113.1	M64 F171	M64-E173 VanDerWaalsContact SD-O 3.35Å; F171-E173 PolarHBondContact O-N 3.5Å
174	D	85.1	Confident	90.4	Very high	103 Å²	103	42.3 Å²	42.3	55%	0.551	23%	0.234	S	C	*	.	S	Bend	trans	-128	154.4	-178.1	-56.2	-70.7	0	0	0	112.3	A176 T177 L178	D174-A176 VanDerWaalsContact C-N 3.29Å; D174-A176 PolarHBondContact O-N 3.31Å; D174-T177 PolarHBondContact O-N 3.03Å; D174-L178 PolarHBondContact O-N 2.92Å; D174-L178 VanDerWaalsContact O-N 3.11Å
175	Y	84.6	Confident	90.3	Very high	70 Å²	70	40.1 Å²	40.1	28%	0.275	22%	0.215	S	C	.	.	H	α-helix	trans	-59.3	-37.2	175.3	-178.9	-95.4	0	0	0	113	I61 K123 L127 T177 L178 F179	I61-Y175 HydrophobicContact CD1-CD2 4.46Å; I61-Y175 HydrophobicContact CD1-CE2 4.49Å; K123-Y175 HydrophobicContact CB-CE2 3.81Å; K123-Y175 HydrophobicContact CG-CE2 4.18Å; K123-Y175 PolarHBondContact O-OH 3.21Å; K123-Y175 VanDerWaalsContact O-OH 3.06Å; L127-Y175 HydrophobicContact CB-CE2 4.4Å; Y175-T177 VanDerWaalsContact C-N 3.32Å; Y175-T177 PolarHBondContact O-N 3.09Å; Y175-L178 WeakPolarHBondContact O-CB 3.43Å; Y175-L178 PolarHBondContact O-N 2.88Å; Y175-F179 HydrophobicContact CE1-CB 4.49Å; Y175-F179 WeakPolarHBondContact O-CB 3.32Å; Y175-F179 PolarHBondContact O-N 3.01Å
176	A	86.9	Confident	90.1	Very high	71 Å²	71	40.1 Å²	40.1	59%	0.587	22%	0.215	S	C	*	.	H	α-helix	trans	-63.2	-40.3	178.6	0	0	0	0	0	111.8	D174 F179 A180	D174-A176 VanDerWaalsContact C-N 3.29Å; D174-A176 PolarHBondContact O-N 3.31Å; A176-F179 PolarHBondContact O-N 3.27Å; A176-A180 WeakPolarHBondContact O-CB 3.16Å; A176-A180 PolarHBondContact O-N 2.52Å
177	T	89.2	Confident	90.1	Very high	41 Å²	41	42.4 Å²	42.4	25%	0.252	23%	0.227	S	C	.	.	H	α-helix	trans	-67.4	-40.7	177	-52.6	0	0	0	0	111	M168 A172 D174 Y175 A180 A181	M168-T177 HydrophobicContact CE-CG2 3.58Å; M168-T177 HydrophobicContact CG-CG2 3.95Å; A172-T177 HydrophobicContact CB-CG2 3.77Å; D174-T177 PolarHBondContact O-N 3.03Å; Y175-T177 VanDerWaalsContact C-N 3.32Å; Y175-T177 PolarHBondContact O-N 3.09Å; T177-A180 PolarHBondContact O-N 3.1Å; T177-A181 VanDerWaalsContact O-CB 3.27Å; T177-A181 WeakPolarHBondContact O-CB 3.25Å; T177-A181 PolarHBondContact O-N 3.4Å
178	L	88	Confident	90	Very high	0 Å²	0	40.3 Å²	40.3	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-61.2	-45.9	172.8	-74.3	172.7	0	0	0	112.4	Y60 M64 L127 F169 A172 D174 Y175 A181 R182	Y60-L178 HydrophobicContact CD1-CD1 3.68Å; Y60-L178 HydrophobicContact CD1-CD2 3.99Å; Y60-L178 HydrophobicContact CD1-CG 4.36Å; Y60-L178 HydrophobicContact CE1-CD1 3.86Å; Y60-L178 HydrophobicContact CE1-CD2 3.65Å; Y60-L178 HydrophobicContact CE1-CG 4.09Å; M64-L178 HydrophobicContact CE-CD1 3.64Å; M64-L178 HydrophobicContact CE-CG 4.19Å; M64-L178 HydrophobicContact SD-CD1 4.21Å; L127-L178 HydrophobicContact CD1-CB 4.04Å; L127-L178 HydrophobicContact CD2-CB 4.4Å; F169-L178 HydrophobicContact CD1-CD2 4.3Å; F169-L178 HydrophobicContact CD2-CD2 3.78Å; F169-L178 HydrophobicContact CE1-CD2 3.99Å; F169-L178 HydrophobicContact CE2-CD2 3.44Å; F169-L178 VanDerWaalsContact CE2-CD2 3.44Å; F169-L178 HydrophobicContact CG-CD2 4.2Å; F169-L178 HydrophobicContact CZ-CD2 3.55Å; A172-L178 HydrophobicContact CB-CD2 3.61Å; A172-L178 HydrophobicContact CB-CG 3.8Å; D174-L178 PolarHBondContact O-N 2.92Å; D174-L178 VanDerWaalsContact O-N 3.11Å; Y175-L178 WeakPolarHBondContact O-CB 3.43Å; Y175-L178 PolarHBondContact O-N 2.88Å; L178-A181 PolarHBondContact O-N 2.92Å; L178-R182 WeakPolarHBondContact O-CB 3.17Å; L178-R182 WeakPolarHBondContact O-CG 3.27Å; L178-R182 PolarHBondContact O-N 3.38Å
179	F	90.3	Very high	90	Very high	82 Å²	82	37.2 Å²	37.2	36%	0.36	20%	0.199	S	C	.	.	H	α-helix	trans	-62.4	-45.9	179.2	-179	-90.3	0	0	0	111.6	V126 L127 S130 Y175 A176 R182 S183	V126-F179 HydrophobicContact CG1-CE2 4.05Å; L127-F179 HydrophobicContact CD1-CB 4.23Å; S130-F179 VanDerWaalsContact CB-CE2 3.45Å; Y175-F179 HydrophobicContact CE1-CB 4.49Å; Y175-F179 WeakPolarHBondContact O-CB 3.32Å; Y175-F179 PolarHBondContact O-N 3.01Å; A176-F179 PolarHBondContact O-N 3.27Å; F179-R182 PolarHBondContact O-N 3.15Å; F179-S183 WeakPolarHBondContact O-CB 3.41Å; F179-S183 PolarHBondContact O-N 3.47Å; F179-S183 PolarHBondContact O-OG 3.06Å
180	A	92.7	Very high	90	Very high	42 Å²	42	37.2 Å²	37.2	35%	0.347	20%	0.199	S	C	.	.	H	α-helix	trans	-62.7	-43.6	176	0	0	0	0	0	111.7	M168 A176 T177 R182 S183 L184	M168-A180 HydrophobicContact CE-CB 3.66Å; A176-A180 WeakPolarHBondContact O-CB 3.16Å; A176-A180 PolarHBondContact O-N 2.52Å; T177-A180 PolarHBondContact O-N 3.1Å; A180-R182 PolarHBondContact O-N 3.44Å; A180-S183 PolarHBondContact O-N 3.27Å; A180-L184 VanDerWaalsContact O-CB 3.25Å; A180-L184 WeakPolarHBondContact O-CB 3.14Å; A180-L184 PolarHBondContact O-N 2.74Å
181	A	92.8	Very high	90	Very high	0 Å²	0	38.4 Å²	38.4	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-61.5	-43.2	176.2	0	0	0	0	0	112.2	S165 M168 F169 T177 L178 L184 Q185	S165-A181 WeakPolarHBondContact CB-O 3.3Å; M168-A181 HydrophobicContact CB-CB 4.19Å; M168-A181 HydrophobicContact CG-CB 4.01Å; M168-A181 HydrophobicContact SD-CB 4.06Å; F169-A181 HydrophobicContact CB-CB 4.13Å; F169-A181 HydrophobicContact CD2-CB 4.01Å; T177-A181 VanDerWaalsContact O-CB 3.27Å; T177-A181 WeakPolarHBondContact O-CB 3.25Å; T177-A181 PolarHBondContact O-N 3.4Å; L178-A181 PolarHBondContact O-N 2.92Å; A181-L184 PolarHBondContact O-N 2.85Å; A181-Q185 PolarHBondContact O-N 3.37Å
182	R	91.4	Very high	90	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-67.4	-42.2	177.9	-78.4	-60	-145.5	147.9	14.4	113.4	I53 L127 S130 K131 F169 L178 F179 A180 L184 Q185 G186	I53-R182 VanDerWaalsContact CD1-NE 3.32Å; L127-R182 HydrophobicContact CD1-CB 4.16Å; L127-R182 HydrophobicContact CD1-CG 3.76Å; L127-R182 HydrophobicContact CG-CG 4.09Å; S130-R182 WeakPolarHBondContact OG-CB 3.28Å; K131-R182 WeakPolarHBondContact CA-O 3.37Å; F169-R182 HydrophobicContact CD2-CG 4.28Å; F169-R182 HydrophobicContact CE2-CG 3.79Å; L178-R182 WeakPolarHBondContact O-CB 3.17Å; L178-R182 WeakPolarHBondContact O-CG 3.27Å; L178-R182 PolarHBondContact O-N 3.38Å; F179-R182 PolarHBondContact O-N 3.15Å; A180-R182 PolarHBondContact O-N 3.44Å; R182-L184 VanDerWaalsContact C-N 3.32Å; R182-Q185 WeakPolarHBondContact O-CB 3.24Å; R182-Q185 PolarHBondContact O-N 2.82Å; R182-G186 PolarHBondContact O-N 3.42Å
183	S	93.9	Very high	90.1	Very high	21 Å²	21	33.8 Å²	33.8	15%	0.147	19%	0.185	C	C	.	.	H	α-helix	trans	-59.4	-49	173.8	-64.8	0	0	0	0	109.1	L134 F179 A180 Q185 G186 L187	L134-S183 WeakPolarHBondContact CD2-O 3.46Å; F179-S183 WeakPolarHBondContact O-CB 3.41Å; F179-S183 PolarHBondContact O-N 3.47Å; F179-S183 PolarHBondContact O-OG 3.06Å; A180-S183 PolarHBondContact O-N 3.27Å; S183-Q185 VanDerWaalsContact C-N 3.3Å; S183-Q185 PolarHBondContact O-N 2.94Å; S183-G186 WeakPolarHBondContact O-CA 3.18Å; S183-G186 PolarHBondContact O-N 2.83Å; S183-L187 PolarHBondContact O-N 3.05Å
184	L	94.4	Very high	90	Very high	55 Å²	55	27.8 Å²	27.8	29%	0.288	16%	0.158	S	C	.	.	H	α-helix	trans	-61.2	-34.1	178.9	-168.8	63.7	0	0	0	113.2	V161 A180 A181 R182 G186 L187 G188	V161-L184 HydrophobicContact CG1-CD1 3.6Å; V161-L184 HydrophobicContact CG1-CG 3.65Å; V161-L184 WeakPolarHBondContact CG1-O 3.42Å; A180-L184 VanDerWaalsContact O-CB 3.25Å; A180-L184 WeakPolarHBondContact O-CB 3.14Å; A180-L184 PolarHBondContact O-N 2.74Å; A181-L184 PolarHBondContact O-N 2.85Å; R182-L184 VanDerWaalsContact C-N 3.32Å; L184-G186 VanDerWaalsContact C-N 3.32Å; L184-G186 PolarHBondContact O-N 3.22Å; L184-L187 HydrophobicContact CD1-CD2 3.9Å; L184-L187 WeakPolarHBondContact O-CB 3.36Å; L184-L187 PolarHBondContact O-N 2.61Å; L184-G188 PolarHBondContact O-N 3.07Å
185	Q	93.5	Very high	90	Very high	1 Å²	1	22.9 Å²	22.9	1%	0.005	13%	0.131	C	C	.	.	H	α-helix	trans	-59.6	-41.1	170	-79.3	172.9	34.4	0	0	112.1	S165 A181 R182 S183 L187 G188 S189	S165-Q185 WeakPolarHBondContact OG-CG 3.46Å; A181-Q185 PolarHBondContact O-N 3.37Å; R182-Q185 WeakPolarHBondContact O-CB 3.24Å; R182-Q185 PolarHBondContact O-N 2.82Å; S183-Q185 VanDerWaalsContact C-N 3.3Å; S183-Q185 PolarHBondContact O-N 2.94Å; Q185-L187 VanDerWaalsContact C-N 3.31Å; Q185-L187 PolarHBondContact O-N 3.38Å; Q185-G188 PolarHBondContact O-N 2.87Å; Q185-G188 VanDerWaalsContact O-N 3.15Å; Q185-S189 VanDerWaalsContact O-CB 3.28Å; Q185-S189 WeakPolarHBondContact O-CB 3Å; Q185-S189 PolarHBondContact O-N 3.49Å
186	G	91.9	Very high	90.1	Very high	0 Å²	0	19.5 Å²	19.5	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-62.4	-36.8	176.6	0	0	0	0	0	113.1	K131 R182 S183 L184 A190	K131-G186 WeakPolarHBondContact O-CA 3.25Å; R182-G186 PolarHBondContact O-N 3.42Å; S183-G186 WeakPolarHBondContact O-CA 3.18Å; S183-G186 PolarHBondContact O-N 2.83Å; L184-G186 VanDerWaalsContact C-N 3.32Å; L184-G186 PolarHBondContact O-N 3.22Å; G186-A190 WeakPolarHBondContact O-CB 3.33Å; G186-A190 PolarHBondContact O-N 3.07Å
187	L	93.4	Very high	89.9	Confident	48 Å²	48	16.9 Å²	16.9	25%	0.251	9%	0.094	S	C	.	.	H	α-helix	trans	-63.3	-45.3	171.8	-178.5	68.9	0	0	0	111.5	L134 V138 V161 S183 L184 Q185 F191	L134-L187 HydrophobicContact CD2-CB 3.86Å; V138-L187 HydrophobicContact CB-CD1 4.31Å; V138-L187 HydrophobicContact CG1-CD1 3.86Å; V138-L187 HydrophobicContact CG2-CD1 3.49Å; V138-L187 VanDerWaalsContact CG2-CD1 3.49Å; V161-L187 HydrophobicContact CG1-CB 4.35Å; V161-L187 HydrophobicContact CG1-CD2 4.36Å; V161-L187 HydrophobicContact CG1-CG 4.45Å; S183-L187 PolarHBondContact O-N 3.05Å; L184-L187 HydrophobicContact CD1-CD2 3.9Å; L184-L187 WeakPolarHBondContact O-CB 3.36Å; L184-L187 PolarHBondContact O-N 2.61Å; Q185-L187 VanDerWaalsContact C-N 3.31Å; Q185-L187 PolarHBondContact O-N 3.38Å; L187-F191 HydrophobicContact CD1-CD2 4.26Å; L187-F191 HydrophobicContact CD1-CE2 3.67Å; L187-F191 HydrophobicContact CG-CD2 4.37Å; L187-F191 HydrophobicContact CG-CE2 4.15Å; L187-F191 VanDerWaalsContact O-CD2 3.25Å; L187-F191 WeakPolarHBondContact O-CD2 3.37Å; L187-F191 PolarHBondContact O-N 2.9Å
188	G	91.8	Very high	89.4	Confident	0 Å²	0	15.3 Å²	15.3	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-64.2	-45.2	179.7	0	0	0	0	0	112.7	G158 L184 Q185 F191 A192	G158-G188 VanDerWaalsContact CA-O 3.29Å; G158-G188 WeakPolarHBondContact CA-O 3.35Å; L184-G188 PolarHBondContact O-N 3.07Å; Q185-G188 PolarHBondContact O-N 2.87Å; Q185-G188 VanDerWaalsContact O-N 3.15Å; G188-F191 PolarHBondContact O-N 2.9Å; G188-A192 WeakPolarHBondContact O-CB 3.5Å; G188-A192 PolarHBondContact O-N 3.43Å
189	S	91.4	Very high	89.1	Confident	0 Å²	0	15.4 Å²	15.4	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-56.5	-52.9	175.6	172.1	0	0	0	0	111.8	D46 K131 Q135 Q185 F191 A192 D193	D46-S189 VanDerWaalsContact CG-OG 3.22Å; D46-S189 WeakPolarHBondContact OD1-CB 3.32Å; D46-S189 PolarHBondContact OD1-OG 3.5Å; D46-S189 PolarHBondContact OD2-OG 3.04Å; K131-S189 PolarHBondContact NZ-OG 3.25Å; K131-S189 VanDerWaalsContact NZ-OG 3.16Å; Q135-S189 PolarHBondContact NE2-OG 3.14Å; Q135-S189 PolarHBondContact OE1-OG 2.87Å; Q135-S189 VanDerWaalsContact OE1-OG 3.09Å; Q185-S189 VanDerWaalsContact O-CB 3.28Å; Q185-S189 WeakPolarHBondContact O-CB 3Å; Q185-S189 PolarHBondContact O-N 3.49Å; S189-F191 VanDerWaalsContact C-N 3.26Å; S189-F191 PolarHBondContact O-N 3.36Å; S189-F191 VanDerWaalsContact O-N 3.16Å; S189-A192 PolarHBondContact O-N 3.38Å; S189-D193 WeakPolarHBondContact O-CB 3.42Å; S189-D193 VanDerWaalsContact O-CG 3.26Å; S189-D193 PolarHBondContact O-N 3.06Å; S189-D193 PolarHBondContact OG-OD2 3.3Å; S189-D193 VanDerWaalsContact OG-OD2 3.06Å
190	A	89.7	Confident	88.7	Confident	0 Å²	0	11.7 Å²	11.7	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-53.2	-42.3	179.1	0	0	0	0	0	113.1	Q135 V138 N139 G186 T194	Q135-A190 HydrophobicContact CG-CB 4.19Å; V138-A190 HydrophobicContact CB-CB 3.76Å; V138-A190 HydrophobicContact CG1-CB 3.52Å; N139-A190 WeakPolarHBondContact OD1-CA 3.39Å; N139-A190 WeakPolarHBondContact OD1-CB 3.47Å; G186-A190 WeakPolarHBondContact O-CB 3.33Å; G186-A190 PolarHBondContact O-N 3.07Å; A190-T194 WeakPolarHBondContact O-CB 3.19Å; A190-T194 WeakPolarHBondContact O-CG2 3.44Å; A190-T194 PolarHBondContact O-N 3.19Å; A190-T194 PolarHBondContact O-OG1 3.37Å
191	F	89	Confident	87.9	Confident	26 Å²	26	10.2 Å²	10.2	11%	0.114	6%	0.058	C	C	.	.	H	α-helix	trans	-75.6	-40.3	176.6	-74.2	-60.9	0	0	0	113	V138 F145 P154 I157 L187 G188 S189 S195	V138-F191 HydrophobicContact CG1-CD2 4.5Å; V138-F191 HydrophobicContact CG1-CE2 4.09Å; V138-F191 HydrophobicContact CG1-CZ 4.13Å; F145-F191 HydrophobicContact CB-CE1 4.48Å; F145-F191 HydrophobicContact CD1-CD1 4.3Å; F145-F191 AromaticContact CD1-CE1 3.65Å; F145-F191 HydrophobicContact CD1-CE1 3.65Å; F145-F191 HydrophobicContact CD1-CZ 4.38Å; F145-F191 HydrophobicContact CE1-CE1 4.14Å; F145-F191 HydrophobicContact CG-CE1 4.22Å; P154-F191 HydrophobicContact CB-CD1 4.2Å; I157-F191 HydrophobicContact CG2-CD2 4.49Å; L187-F191 HydrophobicContact CD1-CD2 4.26Å; L187-F191 HydrophobicContact CD1-CE2 3.67Å; L187-F191 HydrophobicContact CG-CD2 4.37Å; L187-F191 HydrophobicContact CG-CE2 4.15Å; L187-F191 VanDerWaalsContact O-CD2 3.25Å; L187-F191 WeakPolarHBondContact O-CD2 3.37Å; L187-F191 PolarHBondContact O-N 2.9Å; G188-F191 PolarHBondContact O-N 2.9Å; S189-F191 VanDerWaalsContact C-N 3.26Å; S189-F191 PolarHBondContact O-N 3.36Å; S189-F191 VanDerWaalsContact O-N 3.16Å; F191-S195 WeakPolarHBondContact O-CB 3.16Å; F191-S195 PolarHBondContact O-N 2.96Å; F191-S195 VanDerWaalsContact O-N 3.12Å; F191-S195 PolarHBondContact O-OG 3.23Å
192	A	90	Very high	87.1	Confident	1 Å²	1	12.6 Å²	12.6	1%	0.008	7%	0.07	C	C	.	.	H	α-helix	trans	-66.5	-45.2	-178.7	0	0	0	0	0	112.1	L155 M162 G188 S189 G196	L155-A192 HydrophobicContact CD1-CB 4.16Å; M162-A192 HydrophobicContact CE-CB 3.53Å; M162-A192 HydrophobicContact SD-CB 4.47Å; G188-A192 WeakPolarHBondContact O-CB 3.5Å; G188-A192 PolarHBondContact O-N 3.43Å; S189-A192 PolarHBondContact O-N 3.38Å; A192-G196 WeakPolarHBondContact O-CA 3.26Å; A192-G196 PolarHBondContact O-N 2.93Å
193	D	87.6	Confident	86.5	Confident	12 Å²	12	15 Å²	15	6%	0.064	8%	0.081	C	C	.	.	H	α-helix	trans	-69	-50.7	-175	-63.2	-16.7	0	0	0	110.9	L43 S189 S195 I197	L43-D193 HydrophobicContact CD2-CB 4.23Å; L43-D193 WeakPolarHBondContact CD2-OD1 3.41Å; S189-D193 WeakPolarHBondContact O-CB 3.42Å; S189-D193 VanDerWaalsContact O-CG 3.26Å; S189-D193 PolarHBondContact O-N 3.06Å; S189-D193 PolarHBondContact OG-OD2 3.3Å; S189-D193 VanDerWaalsContact OG-OD2 3.06Å; D193-S195 PolarHBondContact O-N 2.82Å; D193-I197 WeakPolarHBondContact O-CB 3.43Å; D193-I197 WeakPolarHBondContact O-CG1 3.4Å; D193-I197 PolarHBondContact O-N 3.29Å; D193-I197 VanDerWaalsContact O-N 3.13Å
194	T	82.5	Confident	85.8	Confident	10 Å²	10	15 Å²	15	6%	0.061	8%	0.078	C	C	.	.	H	α-helix	trans	-64.7	-42.4	179.8	55.5	0	0	0	0	112.2	S142 I146 A190 A198 A422	S142-T194 PolarHBondContact OG-OG1 3.34Å; I146-T194 VanDerWaalsContact CD1-OG1 3.24Å; I146-T194 WeakPolarHBondContact CD1-OG1 3.31Å; A190-T194 WeakPolarHBondContact O-CB 3.19Å; A190-T194 WeakPolarHBondContact O-CG2 3.44Å; A190-T194 PolarHBondContact O-N 3.19Å; A190-T194 PolarHBondContact O-OG1 3.37Å; T194-A198 WeakPolarHBondContact O-CB 3.47Å; T194-A198 PolarHBondContact O-N 3.47Å; T194-A198 VanDerWaalsContact O-N 3.16Å; T194-A422 HydrophobicContact CG2-CB 4.4Å
195	S	84.9	Confident	84.6	Confident	0 Å²	0	16.3 Å²	16.3	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-75	-37.9	-179.2	-50.7	0	0	0	0	112.6	I146 P154 F191 D193 M199	I146-S195 VanDerWaalsContact CD1-OG 3.26Å; I146-S195 WeakPolarHBondContact CD1-OG 3.43Å; I146-S195 WeakPolarHBondContact CG1-OG 3.36Å; P154-S195 WeakPolarHBondContact CB-OG 3.48Å; F191-S195 WeakPolarHBondContact O-CB 3.16Å; F191-S195 PolarHBondContact O-N 2.96Å; F191-S195 VanDerWaalsContact O-N 3.12Å; F191-S195 PolarHBondContact O-OG 3.23Å; D193-S195 PolarHBondContact O-N 2.82Å; S195-M199 WeakPolarHBondContact O-CB 3.29Å; S195-M199 PolarHBondContact O-N 3.48Å
196	G	86.5	Confident	83.7	Confident	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-64.9	-48.7	-179.7	0	0	0	0	0	111.5	V39 A192 M199 I200	V39-G196 WeakPolarHBondContact CG1-O 3.48Å; A192-G196 WeakPolarHBondContact O-CA 3.26Å; A192-G196 PolarHBondContact O-N 2.93Å; G196-M199 WeakPolarHBondContact O-CB 3.35Å; G196-M199 PolarHBondContact O-N 3.32Å; G196-I200 WeakPolarHBondContact O-CG1 3.37Å; G196-I200 PolarHBondContact O-N 2.85Å
197	I	83.2	Confident	82.7	Confident	15 Å²	15	25.5 Å²	25.5	8%	0.077	13%	0.132	C	C	.	.	H	α-helix	trans	-65.7	-42.7	178.2	-64.7	174.6	0	0	0	111	L43 D193 M199 I200 A201 L214 Y421	L43-I197 HydrophobicContact CD1-CG1 4.47Å; D193-I197 WeakPolarHBondContact O-CB 3.43Å; D193-I197 WeakPolarHBondContact O-CG1 3.4Å; D193-I197 PolarHBondContact O-N 3.29Å; D193-I197 VanDerWaalsContact O-N 3.13Å; I197-M199 VanDerWaalsContact C-N 3.32Å; I197-M199 PolarHBondContact O-N 3.3Å; I197-I200 PolarHBondContact O-N 3.44Å; I197-A201 PolarHBondContact O-N 2.85Å; I197-L214 HydrophobicContact CG2-CD2 3.75Å; I197-Y421 HydrophobicContact CD1-CD1 3.97Å; I197-Y421 HydrophobicContact CD1-CG 4.09Å; I197-Y421 HydrophobicContact CG2-CD1 4.18Å; I197-Y421 HydrophobicContact CG2-CD2 3.36Å; I197-Y421 HydrophobicContact CG2-CE2 3.82Å; I197-Y421 HydrophobicContact CG2-CG 3.58Å
198	A	78.3	Confident	81.6	Confident	8 Å²	8	27.8 Å²	27.8	7%	0.066	15%	0.15	C	C	.	.	H	α-helix	trans	-62.2	-38.9	175.7	0	0	0	0	0	112.3	Y151 T194 A201 D202	Y151-A198 HydrophobicContact CD1-CB 3.63Å; Y151-A198 HydrophobicContact CE1-CB 3.75Å; T194-A198 WeakPolarHBondContact O-CB 3.47Å; T194-A198 PolarHBondContact O-N 3.47Å; T194-A198 VanDerWaalsContact O-N 3.16Å; A198-A201 PolarHBondContact O-N 3.46Å; A198-D202 PolarHBondContact O-N 3.35Å
199	M	82.1	Confident	81	Confident	2 Å²	2	32.1 Å²	32.1	1%	0.01	17%	0.17	C	C	.	.	H	α-helix	trans	-63	-42.1	175.7	-176.7	-176.5	-61.3	0	0	111.9	L35 V39 D152 L155 S195 G196 I197 A201 D202 K203 L259	L35-M199 HydrophobicContact CB-SD 4.35Å; L35-M199 HydrophobicContact CD1-SD 4.49Å; L35-M199 HydrophobicContact CD2-SD 3.97Å; L35-M199 HydrophobicContact CG-SD 4.5Å; V39-M199 HydrophobicContact CG2-SD 4.19Å; D152-M199 HydrophobicContact CB-CE 4.28Å; D152-M199 WeakPolarHBondContact OD1-CE 3.17Å; L155-M199 HydrophobicContact CB-CE 4.34Å; L155-M199 HydrophobicContact CD2-CE 3.53Å; L155-M199 HydrophobicContact CD2-SD 4.12Å; S195-M199 WeakPolarHBondContact O-CB 3.29Å; S195-M199 PolarHBondContact O-N 3.48Å; G196-M199 WeakPolarHBondContact O-CB 3.35Å; G196-M199 PolarHBondContact O-N 3.32Å; I197-M199 VanDerWaalsContact C-N 3.32Å; I197-M199 PolarHBondContact O-N 3.3Å; M199-A201 VanDerWaalsContact C-N 3.35Å; M199-D202 PolarHBondContact O-N 2.8Å; M199-K203 HydrophobicContact CG-CG 4.28Å; M199-K203 WeakPolarHBondContact O-CB 3.37Å; M199-K203 WeakPolarHBondContact O-CG 3.35Å; M199-K203 PolarHBondContact O-N 3.13Å; M199-L259 HydrophobicContact CE-CD1 4.41Å
200	I	82.8	Confident	80.3	Confident	4 Å²	4	33.2 Å²	33.2	2%	0.021	18%	0.175	C	C	.	.	H	α-helix	trans	-61.8	-46.4	174.1	-67.2	173	0	0	0	109.9	L36 V39 G196 I197 D202 K203 Y204 A213 L214 A217	L36-I200 HydrophobicContact CD1-CD1 3.62Å; L36-I200 HydrophobicContact CD1-CG1 4.04Å; V39-I200 HydrophobicContact CB-CD1 3.94Å; V39-I200 HydrophobicContact CB-CG1 4.21Å; V39-I200 HydrophobicContact CG1-CD1 3.45Å; V39-I200 VanDerWaalsContact CG1-CD1 3.45Å; V39-I200 HydrophobicContact CG1-CG1 4.04Å; V39-I200 HydrophobicContact CG2-CG1 4.3Å; G196-I200 WeakPolarHBondContact O-CG1 3.37Å; G196-I200 PolarHBondContact O-N 2.85Å; I197-I200 PolarHBondContact O-N 3.44Å; I200-D202 VanDerWaalsContact C-N 3.32Å; I200-D202 PolarHBondContact O-N 3.34Å; I200-K203 PolarHBondContact O-N 2.93Å; I200-Y204 HydrophobicContact CG2-CD2 3.96Å; I200-Y204 HydrophobicContact CG2-CE2 4.44Å; I200-Y204 WeakPolarHBondContact O-CD2 3.37Å; I200-Y204 PolarHBondContact O-N 3.49Å; I200-Y204 VanDerWaalsContact O-N 3.08Å; I200-A213 HydrophobicContact CG2-CB 3.67Å; I200-L214 HydrophobicContact CB-CD2 4.27Å; I200-L214 HydrophobicContact CG2-CD2 3.94Å; I200-L214 HydrophobicContact CG2-CG 4.02Å; I200-A217 HydrophobicContact CD1-CB 3.67Å
201	A	75.3	Confident	79.4	Confident	12 Å²	12	37.1 Å²	37.1	10%	0.099	20%	0.202	C	C	.	.	H	α-helix	trans	-62	-36.2	-179.1	0	0	0	0	0	113.4	I197 A198 M199 Y417	I197-A201 PolarHBondContact O-N 2.85Å; A198-A201 PolarHBondContact O-N 3.46Å; M199-A201 VanDerWaalsContact C-N 3.35Å; A201-Y417 HydrophobicContact CB-CD2 4.3Å; A201-Y417 HydrophobicContact CB-CG 4.2Å
202	D	76.2	Confident	78.9	Confident	50 Å²	50	45.3 Å²	45.3	27%	0.267	23%	0.232	S	C	.	.	H	α-helix	trans	-73.3	-41	175.2	-178	68.2	0	0	0	112.5	Y151 A198 M199 I200 R273	Y151-D202 HydrophobicContact CD2-CB 4.45Å; Y151-D202 HydrophobicContact CE2-CB 3.98Å; A198-D202 PolarHBondContact O-N 3.35Å; M199-D202 PolarHBondContact O-N 2.8Å; I200-D202 VanDerWaalsContact C-N 3.32Å; I200-D202 PolarHBondContact O-N 3.34Å; D202-R273 IonicContact OD2-NH1 3.08Å; D202-R273 PolarHBondContact OD2-NH1 3.02Å; D202-R273 VanDerWaalsContact OD2-NH1 3.08Å
203	K	78.4	Confident	78.5	Confident	49 Å²	49	45.5 Å²	45.5	21%	0.213	23%	0.233	C	C	.	.	H	α-helix	trans	-76.8	-23.1	-173.8	-67.7	-68.2	178.9	-177.9	0	113.7	R32 L35 M199 I200 P205	R32-K203 WeakPolarHBondContact CD-O 3.49Å; R32-K203 HydrophobicContact CG-CB 4.49Å; R32-K203 PolarHBondContact NE-O 3.15Å; L35-K203 HydrophobicContact CD1-CD 4.09Å; L35-K203 HydrophobicContact CD1-CG 4.2Å; M199-K203 HydrophobicContact CG-CG 4.28Å; M199-K203 WeakPolarHBondContact O-CB 3.37Å; M199-K203 WeakPolarHBondContact O-CG 3.35Å; M199-K203 PolarHBondContact O-N 3.13Å; I200-K203 PolarHBondContact O-N 2.93Å; K203-P205 WeakPolarHBondContact O-CD 3.47Å
204	Y	79.4	Confident	78	Confident	22 Å²	22	45.4 Å²	45.4	9%	0.086	23%	0.233	C	C	.	.			trans	-112.6	88.4	176.6	-65.8	-88.1	0	0	0	109.4	R32 L36 I200 E209 R210 A213	R32-Y204 PolarHBondContact O-OH 2.78Å; L36-Y204 HydrophobicContact CB-CE2 4.36Å; I200-Y204 HydrophobicContact CG2-CD2 3.96Å; I200-Y204 HydrophobicContact CG2-CE2 4.44Å; I200-Y204 WeakPolarHBondContact O-CD2 3.37Å; I200-Y204 PolarHBondContact O-N 3.49Å; I200-Y204 VanDerWaalsContact O-N 3.08Å; Y204-E209 HydrophobicContact CD1-CB 4.2Å; Y204-R210 VanDerWaalsContact O-CB 3.32Å; Y204-R210 WeakPolarHBondContact O-CB 3.34Å; Y204-R210 WeakPolarHBondContact O-CD 3.43Å; Y204-A213 HydrophobicContact CD1-CB 4.39Å; Y204-A213 HydrophobicContact CD2-CB 3.9Å; Y204-A213 HydrophobicContact CE1-CB 4.46Å; Y204-A213 HydrophobicContact CE2-CB 4Å; Y204-A213 HydrophobicContact CG-CB 4.11Å
205	P	68.7	Low	77.7	Confident	82 Å²	82	46.8 Å²	46.8	53%	0.532	25%	0.249	S	C	.	.			trans	-74.2	-25.9	-177.1	28.4	-34.7	0	0	0	113.2	K203 E207	K203-P205 WeakPolarHBondContact O-CD 3.47Å; P205-E207 PolarHBondContact O-N 3.33Å
206	E	75	Confident	77.7	Confident	112 Å²	112	49.5 Å²	49.5	52%	0.523	27%	0.265	S	S	.	.	S	Bend	trans	-76.9	122.6	-179.7	-65.3	-178.1	-165.5	0	0	110.8	E209 R210	E206-E209 HydrophobicContact CB-CB 4.24Å; E206-E209 HydrophobicContact CB-CG 4.23Å; E206-E209 PolarHBondContact O-N 2.79Å; E206-E209 VanDerWaalsContact O-N 3.15Å; E206-R210 VanDerWaalsContact O-CB 3.28Å; E206-R210 WeakPolarHBondContact O-CB 3.27Å; E206-R210 PolarHBondContact O-N 3.09Å
207	E	69.7	Low	77.5	Confident	83 Å²	83	49.6 Å²	49.6	39%	0.388	27%	0.266	S	S	.	.	H	α-helix	trans	-41.4	-53.8	177.5	-74	-76.6	-175.4	0	0	114.7	P205 R210 S211 R477	P205-E207 PolarHBondContact O-N 3.33Å; E207-R210 IonicContact OE1-NH2 2.98Å; E207-R210 PolarHBondContact OE1-NH2 3.07Å; E207-R210 IonicContact OE2-CZ 3.73Å; E207-R210 IonicContact OE2-NH2 2.68Å; E207-R210 PolarHBondContact OE2-NH2 3.06Å; E207-S211 WeakPolarHBondContact O-CB 3.4Å; E207-S211 PolarHBondContact O-N 2.55Å; E207-R477 IonicContact OE1-NH2 3.04Å; E207-R477 PolarHBondContact OE1-NH2 3.23Å
208	P	72	Confident	77.3	Confident	96 Å²	96	51.1 Å²	51.1	62%	0.623	27%	0.274	S	S	*	.	H	α-helix	trans	-69.4	-38.6	-178	26.5	-34.6	0	0	0	113.2	R212	P208-R212 WeakPolarHBondContact O-CB 3.3Å; P208-R212 PolarHBondContact O-N 3.16Å; P208-R212 VanDerWaalsContact O-N 3.16Å
209	E	77.8	Confident	77.5	Confident	90 Å²	90	53.3 Å²	53.3	42%	0.421	29%	0.292	S	S	.	.	H	α-helix	trans	-69.1	-39.4	177.8	-64.6	-161.3	149.2	0	0	111.4	Y204 E206 R212 A213	Y204-E209 HydrophobicContact CD1-CB 4.2Å; E206-E209 HydrophobicContact CB-CB 4.24Å; E206-E209 HydrophobicContact CB-CG 4.23Å; E206-E209 PolarHBondContact O-N 2.79Å; E206-E209 VanDerWaalsContact O-N 3.15Å; E209-R212 PolarHBondContact O-N 3.15Å; E209-A213 WeakPolarHBondContact O-CB 3.47Å; E209-A213 PolarHBondContact O-N 3.31Å
210	R	77.4	Confident	77.7	Confident	24 Å²	24	56.9 Å²	56.9	9%	0.091	31%	0.308	C	S	.	.	H	α-helix	trans	-63.8	-50.1	177.2	-172.6	175.4	59.4	-159.6	1.9	112	Y204 E206 E207 R212 A213 L214 Y417	Y204-R210 VanDerWaalsContact O-CB 3.32Å; Y204-R210 WeakPolarHBondContact O-CB 3.34Å; Y204-R210 WeakPolarHBondContact O-CD 3.43Å; E206-R210 VanDerWaalsContact O-CB 3.28Å; E206-R210 WeakPolarHBondContact O-CB 3.27Å; E206-R210 PolarHBondContact O-N 3.09Å; E207-R210 IonicContact OE1-NH2 2.98Å; E207-R210 PolarHBondContact OE1-NH2 3.07Å; E207-R210 IonicContact OE2-CZ 3.73Å; E207-R210 IonicContact OE2-NH2 2.68Å; E207-R210 PolarHBondContact OE2-NH2 3.06Å; R210-R212 VanDerWaalsContact C-N 3.25Å; R210-R212 PolarHBondContact O-N 3.17Å; R210-A213 PolarHBondContact O-N 3.49Å; R210-A213 VanDerWaalsContact O-N 3.14Å; R210-L214 HydrophobicContact CG-CD1 3.91Å; R210-L214 HydrophobicContact CG-CG 4.46Å; R210-L214 WeakPolarHBondContact O-CB 3.48Å; R210-L214 WeakPolarHBondContact O-CG 3.16Å; R210-L214 PolarHBondContact O-N 2.87Å; R210-Y417 VanDerWaalsContact NH2-CZ 3.27Å; R210-Y417 PolarHBondContact NH2-OH 2.95Å
211	S	71.6	Confident	77.8	Confident	81 Å²	81	58.6 Å²	58.6	57%	0.566	32%	0.317	S	S	*	.	H	α-helix	trans	-58.4	-40.4	177.6	-179.3	0	0	0	0	111.1	E207 G215	E207-S211 WeakPolarHBondContact O-CB 3.4Å; E207-S211 PolarHBondContact O-N 2.55Å; S211-G215 PolarHBondContact O-N 3.41Å
212	R	77.9	Confident	78	Confident	199 Å²	199	59.7 Å²	59.7	75%	0.751	32%	0.324	S	S	*	.	H	α-helix	trans	-64.7	-44.4	174	-173.1	178.7	178.3	177.2	1.2	112.6	P208 E209 R210 G215 V216	P208-R212 WeakPolarHBondContact O-CB 3.3Å; P208-R212 PolarHBondContact O-N 3.16Å; P208-R212 VanDerWaalsContact O-N 3.16Å; E209-R212 PolarHBondContact O-N 3.15Å; R210-R212 VanDerWaalsContact C-N 3.25Å; R210-R212 PolarHBondContact O-N 3.17Å; R212-G215 PolarHBondContact O-N 3.43Å; R212-V216 WeakPolarHBondContact O-CG2 3.42Å; R212-V216 PolarHBondContact O-N 3.27Å
213	A	80.4	Confident	78.4	Confident	5 Å²	5	61.6 Å²	61.6	4%	0.041	33%	0.33	C	S	.	.	H	α-helix	trans	-65.2	-43.9	179.3	0	0	0	0	0	112	L36 I200 Y204 E209 R210 V216 A217	L36-A213 HydrophobicContact CD1-CB 4.05Å; L36-A213 HydrophobicContact CD2-CB 4.29Å; I200-A213 HydrophobicContact CG2-CB 3.67Å; Y204-A213 HydrophobicContact CD1-CB 4.39Å; Y204-A213 HydrophobicContact CD2-CB 3.9Å; Y204-A213 HydrophobicContact CE1-CB 4.46Å; Y204-A213 HydrophobicContact CE2-CB 4Å; Y204-A213 HydrophobicContact CG-CB 4.11Å; E209-A213 WeakPolarHBondContact O-CB 3.47Å; E209-A213 PolarHBondContact O-N 3.31Å; R210-A213 PolarHBondContact O-N 3.49Å; R210-A213 VanDerWaalsContact O-N 3.14Å; A213-V216 PolarHBondContact O-N 3.24Å; A213-A217 PolarHBondContact O-N 3.48Å
214	L	78.6	Confident	78.7	Confident	10 Å²	10	59.2 Å²	59.2	5%	0.052	32%	0.32	C	S	.	.	H	α-helix	trans	-63.2	-42.3	173.6	-72.6	169.7	0	0	0	111.7	I197 I200 R210 V216 A217 L218 Y421	I197-L214 HydrophobicContact CG2-CD2 3.75Å; I200-L214 HydrophobicContact CB-CD2 4.27Å; I200-L214 HydrophobicContact CG2-CD2 3.94Å; I200-L214 HydrophobicContact CG2-CG 4.02Å; R210-L214 HydrophobicContact CG-CD1 3.91Å; R210-L214 HydrophobicContact CG-CG 4.46Å; R210-L214 WeakPolarHBondContact O-CB 3.48Å; R210-L214 WeakPolarHBondContact O-CG 3.16Å; R210-L214 PolarHBondContact O-N 2.87Å; L214-V216 VanDerWaalsContact C-N 3.29Å; L214-V216 PolarHBondContact O-N 3.11Å; L214-A217 WeakPolarHBondContact O-CB 3.48Å; L214-A217 PolarHBondContact O-N 3.34Å; L214-A217 VanDerWaalsContact O-N 3.13Å; L214-L218 WeakPolarHBondContact O-CG 3.43Å; L214-L218 PolarHBondContact O-N 3.24Å; L214-Y421 HydrophobicContact CD1-CE2 4.19Å; L214-Y421 HydrophobicContact CD2-CE2 4.31Å
215	G	75.3	Confident	78.8	Confident	39 Å²	39	59.2 Å²	59.2	40%	0.402	32%	0.323	S	S	.	.	H	α-helix	trans	-59.8	-37.9	174.9	0	0	0	0	0	113	S211 R212 A219	S211-G215 PolarHBondContact O-N 3.41Å; R212-G215 PolarHBondContact O-N 3.43Å; G215-A219 WeakPolarHBondContact O-CB 3.16Å; G215-A219 PolarHBondContact O-N 3.36Å
216	V	84.4	Confident	79.2	Confident	56 Å²	56	56.2 Å²	56.2	34%	0.339	30%	0.302	S	S	.	.	H	α-helix	trans	-65.6	-46.2	172.3	174.6	0	0	0	0	110.6	R212 A213 L214 L218 A219 F220	R212-V216 WeakPolarHBondContact O-CG2 3.42Å; R212-V216 PolarHBondContact O-N 3.27Å; A213-V216 PolarHBondContact O-N 3.24Å; L214-V216 VanDerWaalsContact C-N 3.29Å; L214-V216 PolarHBondContact O-N 3.11Å; V216-L218 PolarHBondContact O-N 3.36Å; V216-A219 WeakPolarHBondContact O-CB 3.18Å; V216-A219 PolarHBondContact O-N 3.33Å; V216-F220 HydrophobicContact CG1-CD2 4.09Å; V216-F220 HydrophobicContact CG1-CE2 3.93Å; V216-F220 VanDerWaalsContact O-CD2 3.31Å; V216-F220 WeakPolarHBondContact O-CD2 3.48Å; V216-F220 PolarHBondContact O-N 2.97Å; V216-F220 VanDerWaalsContact O-N 3.16Å
217	A	84.2	Confident	79.6	Confident	2 Å²	2	53.2 Å²	53.2	2%	0.017	29%	0.291	C	S	.	.	H	α-helix	trans	-58.4	-46.5	178.2	0	0	0	0	0	112.8	L43 I200 A213 L214 A219 F220 I221	L43-A217 HydrophobicContact CD1-CB 3.79Å; I200-A217 HydrophobicContact CD1-CB 3.67Å; A213-A217 PolarHBondContact O-N 3.48Å; L214-A217 WeakPolarHBondContact O-CB 3.48Å; L214-A217 PolarHBondContact O-N 3.34Å; L214-A217 VanDerWaalsContact O-N 3.13Å; A217-A219 VanDerWaalsContact C-N 3.33Å; A217-A219 PolarHBondContact O-N 3.38Å; A217-F220 WeakPolarHBondContact O-CB 3.46Å; A217-F220 PolarHBondContact O-N 2.95Å; A217-F220 VanDerWaalsContact O-N 3.14Å; A217-I221 PolarHBondContact O-N 2.99Å
218	L	78.4	Confident	80.4	Confident	48 Å²	48	49.3 Å²	49.3	25%	0.251	27%	0.273	S	S	.	.	H	α-helix	trans	-64	-35.5	176.1	-66.8	173	0	0	0	112.4	L214 V216 F220 I221 S222 L402 Y421	L214-L218 WeakPolarHBondContact O-CG 3.43Å; L214-L218 PolarHBondContact O-N 3.24Å; V216-L218 PolarHBondContact O-N 3.36Å; L218-F220 VanDerWaalsContact C-N 3.27Å; L218-F220 PolarHBondContact O-N 2.9Å; L218-I221 HydrophobicContact CD2-CD1 4.05Å; L218-I221 WeakPolarHBondContact O-CB 3.4Å; L218-I221 PolarHBondContact O-N 3.37Å; L218-S222 PolarHBondContact O-N 3.47Å; L218-L402 HydrophobicContact CD1-CD1 4.12Å; L218-L402 HydrophobicContact CD2-CD1 4.24Å; L218-Y421 HydrophobicContact CD1-CE1 4.41Å; L218-Y421 HydrophobicContact CD2-CE1 4.33Å
219	A	81.6	Confident	80.9	Confident	54 Å²	54	44.9 Å²	44.9	45%	0.446	24%	0.244	S	C	.	.	H	α-helix	trans	-63.8	-33.6	174.8	0	0	0	0	0	112.3	G215 V216 A217 F223	G215-A219 WeakPolarHBondContact O-CB 3.16Å; G215-A219 PolarHBondContact O-N 3.36Å; V216-A219 WeakPolarHBondContact O-CB 3.18Å; V216-A219 PolarHBondContact O-N 3.33Å; A217-A219 VanDerWaalsContact C-N 3.33Å; A217-A219 PolarHBondContact O-N 3.38Å; A219-F223 VanDerWaalsContact O-CB 3.26Å; A219-F223 WeakPolarHBondContact O-CB 3.23Å; A219-F223 PolarHBondContact O-N 3.27Å
220	F	87.3	Confident	81.2	Confident	76 Å²	76	41.1 Å²	41.1	33%	0.333	23%	0.228	S	C	.	.	H	α-helix	trans	-70.5	-33	175.2	-88	-106.7	0	0	0	112.7	C40 L44 V216 A217 L218 F223 G224	C40-F220 HydrophobicContact CB-CB 4.29Å; C40-F220 HydrophobicContact CB-CD1 3.92Å; C40-F220 HydrophobicContact CB-CD2 4.06Å; C40-F220 HydrophobicContact CB-CE1 4.23Å; C40-F220 HydrophobicContact CB-CE2 4.35Å; C40-F220 HydrophobicContact CB-CG 3.83Å; C40-F220 HydrophobicContact CB-CZ 4.43Å; L44-F220 HydrophobicContact CB-CD1 4.19Å; L44-F220 HydrophobicContact CD1-CD1 4.23Å; L44-F220 WeakPolarHBondContact CD1-O 3.38Å; L44-F220 HydrophobicContact CD2-CD1 4.38Å; V216-F220 HydrophobicContact CG1-CD2 4.09Å; V216-F220 HydrophobicContact CG1-CE2 3.93Å; V216-F220 VanDerWaalsContact O-CD2 3.31Å; V216-F220 WeakPolarHBondContact O-CD2 3.48Å; V216-F220 PolarHBondContact O-N 2.97Å; V216-F220 VanDerWaalsContact O-N 3.16Å; A217-F220 WeakPolarHBondContact O-CB 3.46Å; A217-F220 PolarHBondContact O-N 2.95Å; A217-F220 VanDerWaalsContact O-N 3.14Å; L218-F220 VanDerWaalsContact C-N 3.27Å; L218-F220 PolarHBondContact O-N 2.9Å; F220-F223 PolarHBondContact O-N 3.49Å; F220-G224 PolarHBondContact O-N 3.28Å
221	I	84.8	Confident	81.7	Confident	41 Å²	41	42.1 Å²	42.1	21%	0.21	23%	0.233	C	C	.	.	H	α-helix	trans	-57.8	-57.2	170.3	-68.5	178	0	0	0	109.7	L43 N47 A217 L218 F223 G224 S225	L43-I221 HydrophobicContact CB-CD1 4.48Å; L43-I221 HydrophobicContact CB-CG1 3.83Å; L43-I221 HydrophobicContact CD1-CD1 4.23Å; L43-I221 HydrophobicContact CD1-CG1 4.27Å; L43-I221 HydrophobicContact CD2-CD1 4.2Å; L43-I221 HydrophobicContact CD2-CG1 4.42Å; L43-I221 HydrophobicContact CG-CG1 4.4Å; N47-I221 WeakPolarHBondContact ND2-CG2 3.44Å; A217-I221 PolarHBondContact O-N 2.99Å; L218-I221 HydrophobicContact CD2-CD1 4.05Å; L218-I221 WeakPolarHBondContact O-CB 3.4Å; L218-I221 PolarHBondContact O-N 3.37Å; I221-F223 VanDerWaalsContact C-N 3.28Å; I221-F223 PolarHBondContact O-N 3.35Å; I221-G224 PolarHBondContact O-N 3.23Å; I221-G224 VanDerWaalsContact O-N 3.14Å; I221-S225 PolarHBondContact O-N 3.29Å; I221-S225 VanDerWaalsContact O-N 3.07Å; I221-S225 PolarHBondContact O-OG 2.95Å
222	S	79.6	Confident	82.2	Confident	35 Å²	35	38.3 Å²	38.3	25%	0.245	21%	0.206	C	C	.	.	H	α-helix	trans	-57.3	-41	178.1	-67.7	0	0	0	0	112.7	L218 L226 H338	L218-S222 PolarHBondContact O-N 3.47Å; S222-L226 PolarHBondContact O-N 2.93Å; S222-H338 VanDerWaalsContact CB-NE2 3.3Å; S222-H338 WeakPolarHBondContact CB-NE2 3.34Å; S222-H338 PolarHBondContact OG-NE2 3.27Å
223	F	83.4	Confident	82.3	Confident	89 Å²	89	29 Å²	29	39%	0.39	17%	0.173	S	C	.	.	H	α-helix	trans	-65.4	-42.4	177.9	-177.7	-108.8	0	0	0	111.9	L44 A219 F220 I221 L226 V227 F335	L44-F223 HydrophobicContact CD1-CD1 3.59Å; L44-F223 HydrophobicContact CD1-CE1 4.33Å; A219-F223 VanDerWaalsContact O-CB 3.26Å; A219-F223 WeakPolarHBondContact O-CB 3.23Å; A219-F223 PolarHBondContact O-N 3.27Å; F220-F223 PolarHBondContact O-N 3.49Å; I221-F223 VanDerWaalsContact C-N 3.28Å; I221-F223 PolarHBondContact O-N 3.35Å; F223-L226 PolarHBondContact O-N 3.23Å; F223-V227 HydrophobicContact CD1-CG2 4.43Å; F223-V227 HydrophobicContact CD2-CG2 3.86Å; F223-V227 HydrophobicContact CE1-CG2 4.11Å; F223-V227 HydrophobicContact CE2-CG2 3.5Å; F223-V227 VanDerWaalsContact CE2-CG2 3.5Å; F223-V227 HydrophobicContact CG-CG2 4.32Å; F223-V227 HydrophobicContact CZ-CG2 3.64Å; F223-V227 WeakPolarHBondContact O-CB 3.48Å; F223-V227 WeakPolarHBondContact O-CG2 3.49Å; F223-V227 PolarHBondContact O-N 2.9Å; F223-F335 HydrophobicContact CD2-CE2 4.01Å; F223-F335 AromaticContact CD2-CZ 3.88Å; F223-F335 HydrophobicContact CD2-CZ 3.88Å; F223-F335 HydrophobicContact CE2-CZ 4.26Å
224	G	86.3	Confident	82.5	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-62.5	-49.4	179.3	0	0	0	0	0	112.4	L44 M48 F220 I221 L226 A228	L44-G224 VanDerWaalsContact CD1-CA 3.4Å; M48-G224 WeakPolarHBondContact CG-O 3.18Å; F220-G224 PolarHBondContact O-N 3.28Å; I221-G224 PolarHBondContact O-N 3.23Å; I221-G224 VanDerWaalsContact O-N 3.14Å; G224-L226 PolarHBondContact O-N 3.41Å; G224-L226 VanDerWaalsContact O-N 3.12Å; G224-A228 VanDerWaalsContact O-CB 3.26Å; G224-A228 WeakPolarHBondContact O-CB 3.36Å; G224-A228 PolarHBondContact O-N 3.43Å; G224-A228 VanDerWaalsContact O-N 3.15Å
225	S	80.2	Confident	82.7	Confident	22 Å²	22	34.1 Å²	34.1	15%	0.154	20%	0.198	C	C	.	.	H	α-helix	trans	-58.4	-30.6	-179.6	-62.3	0	0	0	0	112.6	N47 M51 I221 P229	N47-S225 WeakPolarHBondContact CB-OG 3.36Å; N47-S225 PolarHBondContact OD1-OG 3.37Å; M51-S225 WeakPolarHBondContact CB-O 3.25Å; M51-S225 VanDerWaalsContact CG-O 3.31Å; M51-S225 WeakPolarHBondContact CG-O 3.27Å; I221-S225 PolarHBondContact O-N 3.29Å; I221-S225 VanDerWaalsContact O-N 3.07Å; I221-S225 PolarHBondContact O-OG 2.95Å; S225-P229 VanDerWaalsContact O-CD 3.28Å; S225-P229 WeakPolarHBondContact O-CD 3.46Å
226	L	77.6	Confident	82.9	Confident	18 Å²	18	33.6 Å²	33.6	9%	0.094	18%	0.184	C	C	.	.	H	α-helix	trans	-98.6	-30.4	-171.4	-152.4	75.5	0	0	0	115	S222 F223 G224 A228 P230 W331 F335	S222-L226 PolarHBondContact O-N 2.93Å; F223-L226 PolarHBondContact O-N 3.23Å; G224-L226 PolarHBondContact O-N 3.41Å; G224-L226 VanDerWaalsContact O-N 3.12Å; L226-A228 VanDerWaalsContact C-N 3.26Å; L226-P230 WeakPolarHBondContact O-CD 3.43Å; L226-W331 HydrophobicContact CD1-CB 4.44Å; L226-F335 HydrophobicContact CB-CD2 4.48Å; L226-F335 HydrophobicContact CD2-CB 3.14Å; L226-F335 HydrophobicContact CD2-CD2 3.27Å; L226-F335 HydrophobicContact CD2-CE2 4.43Å; L226-F335 HydrophobicContact CD2-CG 3.59Å; L226-F335 HydrophobicContact CG-CB 4.34Å; L226-F335 HydrophobicContact CG-CD2 4.46Å
227	V	83.2	Confident	82.6	Confident	50 Å²	50	35.8 Å²	35.8	30%	0.303	19%	0.19	S	C	.	.	H	α-helix	trans	-74.9	-22.5	171.8	173.7	0	0	0	0	111	M48 F223 P230 F231	M48-V227 HydrophobicContact CE-CG1 4.42Å; F223-V227 HydrophobicContact CD1-CG2 4.43Å; F223-V227 HydrophobicContact CD2-CG2 3.86Å; F223-V227 HydrophobicContact CE1-CG2 4.11Å; F223-V227 HydrophobicContact CE2-CG2 3.5Å; F223-V227 VanDerWaalsContact CE2-CG2 3.5Å; F223-V227 HydrophobicContact CG-CG2 4.32Å; F223-V227 HydrophobicContact CZ-CG2 3.64Å; F223-V227 WeakPolarHBondContact O-CB 3.48Å; F223-V227 WeakPolarHBondContact O-CG2 3.49Å; F223-V227 PolarHBondContact O-N 2.9Å; V227-P230 WeakPolarHBondContact O-CD 3.46Å; V227-F231 HydrophobicContact CG1-CB 4.41Å; V227-F231 WeakPolarHBondContact O-CB 3.49Å; V227-F231 PolarHBondContact O-N 2.69Å
228	A	86.8	Confident	82.3	Confident	0 Å²	0	43.5 Å²	43.5	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-64	-46.8	-174.9	0	0	0	0	0	116.3	M48 M51 V52 G224 L226 F231 G232	M48-A228 HydrophobicContact CB-CB 4.17Å; M48-A228 HydrophobicContact CE-CB 4.45Å; M48-A228 HydrophobicContact CG-CB 4.19Å; M48-A228 WeakPolarHBondContact O-CB 3.44Å; M51-A228 HydrophobicContact CB-CB 3.48Å; M51-A228 VanDerWaalsContact CB-CB 3.48Å; V52-A228 HydrophobicContact CB-CB 4.21Å; G224-A228 VanDerWaalsContact O-CB 3.26Å; G224-A228 WeakPolarHBondContact O-CB 3.36Å; G224-A228 PolarHBondContact O-N 3.43Å; G224-A228 VanDerWaalsContact O-N 3.15Å; L226-A228 VanDerWaalsContact C-N 3.26Å; A228-F231 PolarHBondContact O-N 3.33Å; A228-G232 PolarHBondContact O-N 2.89Å
229	P	83.3	Confident	82.4	Confident	4 Å²	4	43.8 Å²	43.8	3%	0.026	23%	0.233	C	C	.	.	H	α-helix	trans	-62.9	-44.7	179.8	-18.6	28.6	0	0	0	112.8	M51 S225 G232 G233 W331	M51-P229 HydrophobicContact CB-CG 4.2Å; S225-P229 VanDerWaalsContact O-CD 3.28Å; S225-P229 WeakPolarHBondContact O-CD 3.46Å; P229-G232 PolarHBondContact O-N 3.12Å; P229-G233 PolarHBondContact O-N 3.45Å; P229-W331 HydrophobicContact CB-CG 4.49Å; P229-W331 HydrophobicContact CG-CB 4.39Å; P229-W331 HydrophobicContact CG-CG 4.32Å
230	P	83.6	Confident	82.2	Confident	10 Å²	10	42.7 Å²	42.7	7%	0.065	23%	0.227	C	C	.	.	H	α-helix	trans	-61.1	-44.8	171.3	-23.8	33.6	0	0	0	113	L226 V227 G232 I234 L332	L226-P230 WeakPolarHBondContact O-CD 3.43Å; V227-P230 WeakPolarHBondContact O-CD 3.46Å; P230-G232 VanDerWaalsContact C-N 3.33Å; P230-G232 PolarHBondContact O-N 2.88Å; P230-I234 WeakPolarHBondContact O-CB 3.36Å; P230-I234 WeakPolarHBondContact O-CD1 3.16Å; P230-I234 VanDerWaalsContact O-CG1 3.22Å; P230-I234 WeakPolarHBondContact O-CG1 3.41Å; P230-I234 PolarHBondContact O-N 2.95Å; P230-L332 HydrophobicContact CB-CD1 3.99Å; P230-L332 HydrophobicContact CG-CB 3.95Å; P230-L332 HydrophobicContact CG-CD1 3.86Å; P230-L332 HydrophobicContact CG-CG 4.38Å
231	F	87.3	Confident	81.7	Confident	46 Å²	46	42.9 Å²	42.9	20%	0.202	23%	0.228	C	C	.	.	H	α-helix	trans	-59.4	-44.4	177.5	173.5	-95.9	0	0	0	111.6	M48 V52 V227 A228 L235 V247 L248	M48-F231 HydrophobicContact CE-CB 4.01Å; M48-F231 HydrophobicContact CE-CD1 3.62Å; M48-F231 HydrophobicContact CE-CD2 4.29Å; M48-F231 HydrophobicContact CE-CE1 4.13Å; M48-F231 HydrophobicContact CE-CG 3.71Å; V52-F231 HydrophobicContact CG2-CD1 3.91Å; V52-F231 HydrophobicContact CG2-CE1 4.4Å; V227-F231 HydrophobicContact CG1-CB 4.41Å; V227-F231 WeakPolarHBondContact O-CB 3.49Å; V227-F231 PolarHBondContact O-N 2.69Å; A228-F231 PolarHBondContact O-N 3.33Å; F231-L235 HydrophobicContact CD2-CD1 4.22Å; F231-L235 HydrophobicContact CD2-CD2 4.42Å; F231-L235 HydrophobicContact CE1-CD2 4.05Å; F231-L235 HydrophobicContact CE2-CD1 4.15Å; F231-L235 HydrophobicContact CE2-CD2 3.7Å; F231-L235 HydrophobicContact CZ-CD2 3.49Å; F231-L235 VanDerWaalsContact CZ-CD2 3.49Å; F231-L235 WeakPolarHBondContact O-CB 3.33Å; F231-L235 PolarHBondContact O-N 3.11Å; F231-L235 VanDerWaalsContact O-N 3.13Å; F231-V247 HydrophobicContact CZ-CB 4.3Å; F231-V247 HydrophobicContact CZ-CG1 3.9Å; F231-L248 HydrophobicContact CE1-CD1 4.2Å; F231-L248 HydrophobicContact CE1-CD2 4.09Å; F231-L248 HydrophobicContact CE1-CG 3.99Å
232	G	82.4	Confident	81.7	Confident	0 Å²	0	45.9 Å²	45.9	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-66.7	-50.7	179.1	0	0	0	0	0	112.6	A228 P229 P230 I234 Y236	A228-G232 PolarHBondContact O-N 2.89Å; P229-G232 PolarHBondContact O-N 3.12Å; P230-G232 VanDerWaalsContact C-N 3.33Å; P230-G232 PolarHBondContact O-N 2.88Å; G232-I234 PolarHBondContact O-N 3.39Å; G232-Y236 WeakPolarHBondContact O-CB 3.45Å; G232-Y236 PolarHBondContact O-N 2.9Å
233	G	79.9	Confident	82.2	Confident	5 Å²	5	46.5 Å²	46.5	5%	0.052	24%	0.239	C	C	.	.	H	α-helix	trans	-60.2	-47	180	0	0	0	0	0	112.7	P229 Y236 E237	P229-G233 PolarHBondContact O-N 3.45Å; G233-Y236 PolarHBondContact O-N 3.49Å; G233-E237 PolarHBondContact O-N 3.2Å; G233-E237 VanDerWaalsContact O-N 3.11Å
234	I	84.1	Confident	82.4	Confident	79 Å²	79	42.3 Å²	42.3	41%	0.405	22%	0.22	S	C	.	.	H	α-helix	trans	-66.1	-51.8	-179.3	-65.5	169.2	0	0	0	110.9	P230 G232 Y236 E237 F238	P230-I234 WeakPolarHBondContact O-CB 3.36Å; P230-I234 WeakPolarHBondContact O-CD1 3.16Å; P230-I234 VanDerWaalsContact O-CG1 3.22Å; P230-I234 WeakPolarHBondContact O-CG1 3.41Å; P230-I234 PolarHBondContact O-N 2.95Å; G232-I234 PolarHBondContact O-N 3.39Å; I234-Y236 VanDerWaalsContact C-N 3.25Å; I234-Y236 PolarHBondContact O-N 3.19Å; I234-E237 PolarHBondContact O-N 3.31Å; I234-F238 HydrophobicContact CG2-CD2 3.73Å; I234-F238 HydrophobicContact CG2-CE2 3.97Å; I234-F238 VanDerWaalsContact O-CD2 3.22Å; I234-F238 WeakPolarHBondContact O-CD2 3.37Å; I234-F238 PolarHBondContact O-N 3.39Å; I234-F238 VanDerWaalsContact O-N 3.1Å
235	L	83.8	Confident	82.7	Confident	42 Å²	42	42.3 Å²	42.3	22%	0.22	22%	0.22	C	C	.	.	H	α-helix	trans	-65.4	-32.3	-179.1	-94.2	63.2	0	0	0	112.1	F231 A239 G240 V243 P244 V247	F231-L235 HydrophobicContact CD2-CD1 4.22Å; F231-L235 HydrophobicContact CD2-CD2 4.42Å; F231-L235 HydrophobicContact CE1-CD2 4.05Å; F231-L235 HydrophobicContact CE2-CD1 4.15Å; F231-L235 HydrophobicContact CE2-CD2 3.7Å; F231-L235 HydrophobicContact CZ-CD2 3.49Å; F231-L235 VanDerWaalsContact CZ-CD2 3.49Å; F231-L235 WeakPolarHBondContact O-CB 3.33Å; F231-L235 PolarHBondContact O-N 3.11Å; F231-L235 VanDerWaalsContact O-N 3.13Å; L235-A239 WeakPolarHBondContact O-CA 3.35Å; L235-A239 WeakPolarHBondContact O-CB 3Å; L235-A239 PolarHBondContact O-N 2.93Å; L235-G240 PolarHBondContact O-N 2.89Å; L235-V243 HydrophobicContact CD2-CG1 4.38Å; L235-P244 HydrophobicContact CB-CB 4.33Å; L235-P244 HydrophobicContact CB-CG 3.73Å; L235-V247 HydrophobicContact CD2-CG2 4.28Å
236	Y	79.8	Confident	83.3	Confident	28 Å²	28	44.5 Å²	44.5	11%	0.11	23%	0.23	C	C	.	.	H	α-helix	trans	-61.5	-48.4	175.5	-176.8	-103.5	0	0	0	111.5	I56 D59 G232 G233 I234 G240 K241 E324	I56-Y236 HydrophobicContact CB-CD2 4.46Å; I56-Y236 HydrophobicContact CD1-CD2 4.33Å; I56-Y236 HydrophobicContact CG1-CD2 3.98Å; I56-Y236 HydrophobicContact CG1-CG 4.19Å; I56-Y236 HydrophobicContact CG2-CD2 3.89Å; I56-Y236 HydrophobicContact CG2-CE2 3.85Å; D59-Y236 PolarHBondContact OD2-OH 3.45Å; G232-Y236 WeakPolarHBondContact O-CB 3.45Å; G232-Y236 PolarHBondContact O-N 2.9Å; G233-Y236 PolarHBondContact O-N 3.49Å; I234-Y236 VanDerWaalsContact C-N 3.25Å; I234-Y236 PolarHBondContact O-N 3.19Å; Y236-G240 VanDerWaalsContact O-CA 3.25Å; Y236-G240 WeakPolarHBondContact O-CA 3.21Å; Y236-G240 PolarHBondContact O-N 3.46Å; Y236-K241 HydrophobicContact CD2-CB 4.21Å; Y236-K241 HydrophobicContact CE2-CB 3.62Å; Y236-E324 WeakPolarHBondContact CE1-OE2 3.23Å
237	E	76.8	Confident	84	Confident	102 Å²	102	46.5 Å²	46.5	48%	0.477	24%	0.243	S	C	.	.	H	α-helix	trans	-66.8	-43.5	-178.4	-171.6	176.1	-179.6	0	0	112.5	G233 I234 W325	G233-E237 PolarHBondContact O-N 3.2Å; G233-E237 VanDerWaalsContact O-N 3.11Å; I234-E237 PolarHBondContact O-N 3.31Å; E237-W325 WeakPolarHBondContact OE2-CB 3.32Å
238	F	79.2	Confident	84.5	Confident	165 Å²	165	44.3 Å²	44.3	72%	0.724	23%	0.229	S	C	*	.	H	α-helix	trans	-87.1	-33.1	-173.8	-72.5	-71.8	0	0	0	114.7	I234	I234-F238 HydrophobicContact CG2-CD2 3.73Å; I234-F238 HydrophobicContact CG2-CE2 3.97Å; I234-F238 VanDerWaalsContact O-CD2 3.22Å; I234-F238 WeakPolarHBondContact O-CD2 3.37Å; I234-F238 PolarHBondContact O-N 3.39Å; I234-F238 VanDerWaalsContact O-N 3.1Å
239	A	79.1	Confident	84.8	Confident	54 Å²	54	44.4 Å²	44.4	45%	0.446	23%	0.23	S	C	.	.	H	α-helix	trans	-122.7	-2.8	-169.3	0	0	0	0	0	113.5	L235 V243	L235-A239 WeakPolarHBondContact O-CA 3.35Å; L235-A239 WeakPolarHBondContact O-CB 3Å; L235-A239 PolarHBondContact O-N 2.93Å; A239-V243 HydrophobicContact CB-CB 3.76Å; A239-V243 HydrophobicContact CB-CG1 3.76Å; A239-V243 HydrophobicContact CB-CG2 3.79Å; A239-V243 WeakPolarHBondContact O-CG2 3.48Å
240	G	79.1	Confident	85.4	Confident	30 Å²	30	46.1 Å²	46.1	31%	0.309	25%	0.245	S	C	.	.			trans	82.8	172.4	175.8	0	0	0	0	0	114.4	L235 Y236 R242 V243 P244	L235-G240 PolarHBondContact O-N 2.89Å; Y236-G240 VanDerWaalsContact O-CA 3.25Å; Y236-G240 WeakPolarHBondContact O-CA 3.21Å; Y236-G240 PolarHBondContact O-N 3.46Å; G240-R242 VanDerWaalsContact C-N 3.28Å; G240-R242 PolarHBondContact O-N 2.95Å; G240-V243 PolarHBondContact O-N 2.92Å; G240-P244 WeakPolarHBondContact O-CD 3.44Å
241	K	75.6	Confident	85.9	Confident	81 Å²	81	48.6 Å²	48.6	35%	0.352	26%	0.259	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55	-29.4	-166.2	72.2	-169.2	-167.6	168.5	0	117.2	Y60 Y236 F245	Y60-K241 HydrophobicContact CD2-CB 4.29Å; Y60-K241 HydrophobicContact CD2-CD 4.19Å; Y60-K241 HydrophobicContact CE2-CB 4.15Å; Y60-K241 HydrophobicContact CE2-CD 3.7Å; Y60-K241 HydrophobicContact CE2-CG 4.09Å; Y236-K241 HydrophobicContact CD2-CB 4.21Å; Y236-K241 HydrophobicContact CE2-CB 3.62Å; K241-F245 WeakPolarHBondContact O-CD2 3.22Å
242	R	85.7	Confident	86.2	Confident	103 Å²	103	46.4 Å²	46.4	39%	0.389	25%	0.25	S	C	.	.	T	Hydrogen-bonded Turn	trans	-86.1	-26.6	-172.9	-59	-172.7	174.3	160.7	-2.6	113	A170 G240 F245 L246	A170-R242 WeakPolarHBondContact O-CG 3.26Å; G240-R242 VanDerWaalsContact C-N 3.28Å; G240-R242 PolarHBondContact O-N 2.95Å; R242-F245 PolarHBondContact O-N 2.98Å; R242-L246 HydrophobicContact CB-CD1 4.26Å; R242-L246 WeakPolarHBondContact O-CG 3.47Å; R242-L246 PolarHBondContact O-N 3.32Å; R242-L246 VanDerWaalsContact O-N 3.08Å
243	V	88.9	Confident	86.8	Confident	49 Å²	49	51 Å²	51	30%	0.297	27%	0.27	S	S	.	.	H	α-helix	trans	-69.7	-44.7	-166.6	177.8	0	0	0	0	113.6	L235 A239 G240 F245 L246 V247	L235-V243 HydrophobicContact CD2-CG1 4.38Å; A239-V243 HydrophobicContact CB-CB 3.76Å; A239-V243 HydrophobicContact CB-CG1 3.76Å; A239-V243 HydrophobicContact CB-CG2 3.79Å; A239-V243 WeakPolarHBondContact O-CG2 3.48Å; G240-V243 PolarHBondContact O-N 2.92Å; V243-F245 VanDerWaalsContact C-N 3.25Å; V243-F245 PolarHBondContact O-N 3.49Å; V243-L246 PolarHBondContact O-N 2.9Å; V243-V247 HydrophobicContact CG1-CG2 4.18Å; V243-V247 WeakPolarHBondContact O-CG2 3.22Å; V243-V247 PolarHBondContact O-N 3.16Å
244	P	88.9	Confident	87.5	Confident	0 Å²	0	57.1 Å²	57.1	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-53.2	-44.4	176.6	-21.3	26.9	0	0	0	112.5	V52 I56 L235 G240 L248	V52-P244 HydrophobicContact CG2-CB 4.24Å; I56-P244 HydrophobicContact CD1-CB 4.24Å; I56-P244 HydrophobicContact CD1-CG 4.05Å; L235-P244 HydrophobicContact CB-CB 4.33Å; L235-P244 HydrophobicContact CB-CG 3.73Å; G240-P244 WeakPolarHBondContact O-CD 3.44Å; P244-L248 WeakPolarHBondContact O-CG 3.36Å; P244-L248 PolarHBondContact O-N 3.39Å; P244-L248 VanDerWaalsContact O-N 3.15Å
245	F	90.7	Very high	88	Confident	0 Å²	0	53.7 Å²	53.7	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-71.1	-40.7	-179.1	-59.1	-63.2	0	0	0	112.9	V52 I53 I56 T166 F169 A170 K241 R242 V243 V247 L248 A249	V52-F245 HydrophobicContact CG1-CE1 3.99Å; I53-F245 HydrophobicContact CD1-CE1 3.8Å; I53-F245 HydrophobicContact CD1-CZ 4.41Å; I53-F245 HydrophobicContact CG1-CE1 3.43Å; I53-F245 VanDerWaalsContact CG1-CE1 3.43Å; I53-F245 HydrophobicContact CG1-CZ 3.76Å; I56-F245 HydrophobicContact CD1-CE2 4.06Å; I56-F245 HydrophobicContact CD1-CZ 3.83Å; I56-F245 HydrophobicContact CG2-CE2 4.17Å; I56-F245 HydrophobicContact CG2-CZ 4.3Å; T166-F245 HydrophobicContact CG2-CB 4.11Å; T166-F245 HydrophobicContact CG2-CD1 4.5Å; T166-F245 WeakPolarHBondContact CG2-O 3.37Å; F169-F245 AromaticContact CD1-CD1 3.78Å; F169-F245 HydrophobicContact CD1-CD1 3.78Å; F169-F245 AromaticContact CD1-CD2 3.98Å; F169-F245 HydrophobicContact CD1-CD2 3.98Å; F169-F245 AromaticContact CD1-CE1 3.55Å; F169-F245 HydrophobicContact CD1-CE1 3.55Å; F169-F245 AromaticContact CD1-CE2 3.74Å; F169-F245 HydrophobicContact CD1-CE2 3.74Å; F169-F245 HydrophobicContact CD1-CG 4Å; F169-F245 AromaticContact CD1-CZ 3.54Å; F169-F245 HydrophobicContact CD1-CZ 3.54Å; F169-F245 HydrophobicContact CE1-CD1 4.34Å; F169-F245 HydrophobicContact CE1-CD2 4.41Å; F169-F245 AromaticContact CE1-CE1 3.65Å; F169-F245 HydrophobicContact CE1-CE1 3.65Å; F169-F245 AromaticContact CE1-CE2 3.71Å; F169-F245 HydrophobicContact CE1-CE2 3.71Å; F169-F245 AromaticContact CE1-CZ 3.29Å; F169-F245 HydrophobicContact CE1-CZ 3.29Å; F169-F245 HydrophobicContact CZ-CZ 4.41Å; A170-F245 HydrophobicContact CB-CB 3.71Å; K241-F245 WeakPolarHBondContact O-CD2 3.22Å; R242-F245 PolarHBondContact O-N 2.98Å; V243-F245 VanDerWaalsContact C-N 3.25Å; V243-F245 PolarHBondContact O-N 3.49Å; F245-V247 VanDerWaalsContact C-N 3.32Å; F245-V247 PolarHBondContact O-N 3.21Å; F245-L248 PolarHBondContact O-N 2.87Å; F245-A249 VanDerWaalsContact O-CB 3.27Å; F245-A249 WeakPolarHBondContact O-CB 3.38Å; F245-A249 PolarHBondContact O-N 3.08Å
246	L	93	Very high	88.4	Confident	69 Å²	69	52.2 Å²	52.2	36%	0.361	27%	0.272	S	S	.	.	H	α-helix	trans	-65.7	-35.8	177.5	-71.5	174.6	0	0	0	112.2	A170 F171 R242 V243 A250	A170-L246 HydrophobicContact CB-CD2 4.22Å; A170-L246 HydrophobicContact CB-CG 4.28Å; F171-L246 HydrophobicContact CE2-CD2 4.15Å; F171-L246 HydrophobicContact CZ-CD2 4.4Å; R242-L246 HydrophobicContact CB-CD1 4.26Å; R242-L246 WeakPolarHBondContact O-CG 3.47Å; R242-L246 PolarHBondContact O-N 3.32Å; R242-L246 VanDerWaalsContact O-N 3.08Å; V243-L246 PolarHBondContact O-N 2.9Å; L246-A250 WeakPolarHBondContact O-CB 3.38Å; L246-A250 PolarHBondContact O-N 2.87Å
247	V	93.2	Very high	88.9	Confident	59 Å²	59	55.3 Å²	55.3	36%	0.358	29%	0.29	S	S	.	.	H	α-helix	trans	-64.6	-49.1	174.3	174	0	0	0	0	110.3	F231 L235 V243 F245 A249 A250 V251	F231-V247 HydrophobicContact CZ-CB 4.3Å; F231-V247 HydrophobicContact CZ-CG1 3.9Å; L235-V247 HydrophobicContact CD2-CG2 4.28Å; V243-V247 HydrophobicContact CG1-CG2 4.18Å; V243-V247 WeakPolarHBondContact O-CG2 3.22Å; V243-V247 PolarHBondContact O-N 3.16Å; F245-V247 VanDerWaalsContact C-N 3.32Å; F245-V247 PolarHBondContact O-N 3.21Å; V247-A249 VanDerWaalsContact C-N 3.34Å; V247-A249 PolarHBondContact O-N 3.08Å; V247-A250 WeakPolarHBondContact O-CB 3.46Å; V247-A250 PolarHBondContact O-N 3.48Å; V247-V251 WeakPolarHBondContact O-CG2 3.43Å; V247-V251 PolarHBondContact O-N 3.15Å
248	L	92.6	Very high	89.5	Confident	5 Å²	5	53.6 Å²	53.6	3%	0.026	28%	0.283	C	S	.	.	H	α-helix	trans	-64	-38.2	178.2	-67.1	172.7	0	0	0	112.3	L45 M48 L49 V52 T166 F231 P244 F245 V251 S252	L45-L248 HydrophobicContact CD2-CD2 3.99Å; M48-L248 HydrophobicContact CB-CD2 4.14Å; M48-L248 HydrophobicContact CE-CD2 4.12Å; M48-L248 HydrophobicContact SD-CD2 4.14Å; L49-L248 HydrophobicContact CD2-CB 3.85Å; L49-L248 HydrophobicContact CD2-CD1 3.64Å; L49-L248 HydrophobicContact CD2-CG 4.37Å; L49-L248 HydrophobicContact CG-CB 4.42Å; L49-L248 HydrophobicContact CG-CD1 4.15Å; V52-L248 HydrophobicContact CB-CD1 4.29Å; V52-L248 HydrophobicContact CG1-CD1 3.78Å; V52-L248 HydrophobicContact CG2-CD1 4.32Å; T166-L248 HydrophobicContact CG2-CB 4.41Å; F231-L248 HydrophobicContact CE1-CD1 4.2Å; F231-L248 HydrophobicContact CE1-CD2 4.09Å; F231-L248 HydrophobicContact CE1-CG 3.99Å; P244-L248 WeakPolarHBondContact O-CG 3.36Å; P244-L248 PolarHBondContact O-N 3.39Å; P244-L248 VanDerWaalsContact O-N 3.15Å; F245-L248 PolarHBondContact O-N 2.87Å; L248-V251 PolarHBondContact O-N 3.06Å; L248-S252 WeakPolarHBondContact O-CB 3.34Å; L248-S252 PolarHBondContact O-N 3.06Å
249	A	94.2	Very high	90	Very high	2 Å²	2	45.7 Å²	45.7	2%	0.017	25%	0.249	C	C	.	.	H	α-helix	trans	-62	-42.7	173.1	0	0	0	0	0	111.6	F163 T166 V167 F245 V247 V251 S252 F253	F163-A249 HydrophobicContact CD2-CB 4Å; F163-A249 VanDerWaalsContact CD2-O 3.22Å; F163-A249 WeakPolarHBondContact CD2-O 3.12Å; F163-A249 HydrophobicContact CE2-CB 4.11Å; T166-A249 HydrophobicContact CG2-CB 3.88Å; V167-A249 HydrophobicContact CG2-CB 3.8Å; F245-A249 VanDerWaalsContact O-CB 3.27Å; F245-A249 WeakPolarHBondContact O-CB 3.38Å; F245-A249 PolarHBondContact O-N 3.08Å; V247-A249 VanDerWaalsContact C-N 3.34Å; V247-A249 PolarHBondContact O-N 3.08Å; A249-V251 PolarHBondContact O-N 3.23Å; A249-S252 PolarHBondContact O-N 2.95Å; A249-F253 WeakPolarHBondContact O-CB 3.35Å; A249-F253 PolarHBondContact O-N 3.26Å
250	A	95.3	Very high	90.4	Very high	40 Å²	40	46.6 Å²	46.6	33%	0.331	25%	0.246	S	C	.	.	H	α-helix	trans	-61.7	-44.5	176.9	0	0	0	0	0	111.6	L246 V247 F253 F254	L246-A250 WeakPolarHBondContact O-CB 3.38Å; L246-A250 PolarHBondContact O-N 2.87Å; V247-A250 WeakPolarHBondContact O-CB 3.46Å; V247-A250 PolarHBondContact O-N 3.48Å; A250-F253 PolarHBondContact O-N 3.05Å; A250-F254 HydrophobicContact CB-CE2 4.48Å; A250-F254 WeakPolarHBondContact O-CD2 3.25Å; A250-F254 PolarHBondContact O-N 3.43Å
251	V	94.7	Very high	90.6	Very high	61 Å²	61	47.7 Å²	47.7	37%	0.37	25%	0.252	S	S	.	.	H	α-helix	trans	-62.5	-44.2	177	-178.5	0	0	0	0	110.8	V41 L45 V247 L248 A249 F253 F254 D255	V41-V251 HydrophobicContact CG1-CG1 3.98Å; L45-V251 HydrophobicContact CD1-CG1 4.05Å; L45-V251 HydrophobicContact CD2-CB 3.89Å; L45-V251 HydrophobicContact CD2-CG1 3.8Å; L45-V251 HydrophobicContact CG-CG1 4.21Å; V247-V251 WeakPolarHBondContact O-CG2 3.43Å; V247-V251 PolarHBondContact O-N 3.15Å; L248-V251 PolarHBondContact O-N 3.06Å; A249-V251 PolarHBondContact O-N 3.23Å; V251-F253 VanDerWaalsContact C-N 3.34Å; V251-F253 PolarHBondContact O-N 3.45Å; V251-F254 PolarHBondContact O-N 3.36Å; V251-D255 WeakPolarHBondContact O-CB 3.34Å; V251-D255 PolarHBondContact O-N 2.91Å
252	S	93.8	Very high	90.9	Very high	0 Å²	0	44.2 Å²	44.2	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-60	-41.6	175.3	-178.9	0	0	0	0	112.8	L45 L159 L248 A249 D255 A256	L45-S252 VanDerWaalsContact CD1-CA 3.49Å; L159-S252 PolarHBondContact O-OG 3.25Å; L248-S252 WeakPolarHBondContact O-CB 3.34Å; L248-S252 PolarHBondContact O-N 3.06Å; A249-S252 PolarHBondContact O-N 2.95Å; S252-D255 PolarHBondContact O-N 3.29Å; S252-A256 WeakPolarHBondContact O-CB 3.42Å; S252-A256 PolarHBondContact O-N 3.33Å
253	F	95.3	Very high	90.1	Very high	97 Å²	97	40 Å²	40	43%	0.425	23%	0.225	S	C	.	.	H	α-helix	trans	-64	-45.6	176.7	177.7	-101.2	0	0	0	112.4	F163 A249 A250 V251 D255 A256 L257	F163-F253 HydrophobicContact CD2-CB 3.79Å; F163-F253 HydrophobicContact CE1-CD2 4.24Å; F163-F253 HydrophobicContact CE2-CB 3.78Å; F163-F253 HydrophobicContact CE2-CD2 4.29Å; F163-F253 HydrophobicContact CE2-CG 4.33Å; F163-F253 HydrophobicContact CG-CB 4.42Å; F163-F253 HydrophobicContact CZ-CB 4.43Å; F163-F253 HydrophobicContact CZ-CD2 4.1Å; A249-F253 WeakPolarHBondContact O-CB 3.35Å; A249-F253 PolarHBondContact O-N 3.26Å; A250-F253 PolarHBondContact O-N 3.05Å; V251-F253 VanDerWaalsContact C-N 3.34Å; V251-F253 PolarHBondContact O-N 3.45Å; F253-D255 VanDerWaalsContact C-N 3.33Å; F253-A256 PolarHBondContact O-N 2.96Å; F253-L257 WeakPolarHBondContact O-CB 3.36Å; F253-L257 PolarHBondContact O-N 3.04Å
254	F	94.6	Very high	89.2	Confident	133 Å²	133	44.2 Å²	44.2	58%	0.583	24%	0.239	S	C	*	.	H	α-helix	trans	-66.8	-35.8	177.8	-74.2	-60	0	0	0	112.3	A250 V251 L257 L258	A250-F254 HydrophobicContact CB-CE2 4.48Å; A250-F254 WeakPolarHBondContact O-CD2 3.25Å; A250-F254 PolarHBondContact O-N 3.43Å; V251-F254 PolarHBondContact O-N 3.36Å; F254-L257 PolarHBondContact O-N 3.1Å; F254-L258 WeakPolarHBondContact O-CB 3.17Å; F254-L258 PolarHBondContact O-N 3.13Å
255	D	93.4	Very high	87.8	Confident	7 Å²	7	44.6 Å²	44.6	4%	0.037	24%	0.241	C	C	.	.	H	α-helix	trans	-66.4	-43.1	175.8	-166.2	48.4	0	0	0	111.9	I38 V41 L159 V251 S252 F253 L257 L258 L259	I38-D255 WeakPolarHBondContact CA-OD1 3.05Å; V41-D255 HydrophobicContact CG1-CB 3.89Å; L159-D255 HydrophobicContact CD2-CB 4.34Å; L159-D255 WeakPolarHBondContact CD2-OD2 3.28Å; V251-D255 WeakPolarHBondContact O-CB 3.34Å; V251-D255 PolarHBondContact O-N 2.91Å; S252-D255 PolarHBondContact O-N 3.29Å; F253-D255 VanDerWaalsContact C-N 3.33Å; D255-L257 VanDerWaalsContact C-N 3.33Å; D255-L257 PolarHBondContact O-N 3.5Å; D255-L258 PolarHBondContact O-N 3.3Å; D255-L259 PolarHBondContact O-N 3.44Å
256	A	92.2	Very high	86.3	Confident	12 Å²	12	51.6 Å²	51.6	10%	0.099	27%	0.272	C	S	.	.	H	α-helix	trans	-60	-41.2	172.6	0	0	0	0	0	112.6	L156 L159 S252 F253 L259 L260	L156-A256 HydrophobicContact CD1-CB 4.12Å; L159-A256 HydrophobicContact CB-CB 4Å; S252-A256 WeakPolarHBondContact O-CB 3.42Å; S252-A256 PolarHBondContact O-N 3.33Å; F253-A256 PolarHBondContact O-N 2.96Å; A256-L259 PolarHBondContact O-N 3.25Å; A256-L260 PolarHBondContact O-N 2.92Å
257	L	90.9	Very high	84.5	Confident	93 Å²	93	51 Å²	51	49%	0.487	27%	0.274	S	S	.	.	H	α-helix	trans	-66.8	-40.1	176.7	-176.7	62.4	0	0	0	111.7	F253 F254 D255 L260 A261	F253-L257 WeakPolarHBondContact O-CB 3.36Å; F253-L257 PolarHBondContact O-N 3.04Å; F254-L257 PolarHBondContact O-N 3.1Å; D255-L257 VanDerWaalsContact C-N 3.33Å; D255-L257 PolarHBondContact O-N 3.5Å; L257-L260 PolarHBondContact O-N 3.48Å; L257-A261 PolarHBondContact O-N 3.46Å
258	L	89.9	Confident	82.4	Confident	65 Å²	65	51.7 Å²	51.7	34%	0.34	29%	0.286	S	S	.	.	H	α-helix	trans	-64	-42.4	175.9	-173.9	61.1	0	0	0	110.8	I38 F254 D255 L260 A261 V262	I38-L258 HydrophobicContact CD1-CD2 4.37Å; I38-L258 HydrophobicContact CD1-CG 4Å; I38-L258 HydrophobicContact CG1-CB 4.36Å; I38-L258 HydrophobicContact CG1-CD2 3.77Å; I38-L258 HydrophobicContact CG1-CG 3.89Å; F254-L258 WeakPolarHBondContact O-CB 3.17Å; F254-L258 PolarHBondContact O-N 3.13Å; D255-L258 PolarHBondContact O-N 3.3Å; L258-L260 PolarHBondContact O-N 3.35Å; L258-A261 PolarHBondContact O-N 2.99Å; L258-V262 HydrophobicContact CD1-CG2 4.04Å; L258-V262 HydrophobicContact CG-CG2 4.29Å; L258-V262 WeakPolarHBondContact O-CB 3.26Å; L258-V262 WeakPolarHBondContact O-CG2 3.31Å; L258-V262 PolarHBondContact O-N 2.94Å
259	L	89.1	Confident	80.5	Confident	0 Å²	0	54.7 Å²	54.7	0%	0	31%	0.311	C	S	.	.	H	α-helix	trans	-58.9	-46.8	173.7	-178.7	62.5	0	0	0	111.9	L35 I38 L155 L156 L159 M199 D255 A256 A261 V262 A263	L35-L259 HydrophobicContact CD2-CD1 4.26Å; I38-L259 HydrophobicContact CD1-CB 4.4Å; I38-L259 HydrophobicContact CD1-CD1 4.38Å; I38-L259 HydrophobicContact CG2-CB 4.05Å; I38-L259 HydrophobicContact CG2-CD1 4.13Å; L155-L259 HydrophobicContact CB-CD2 4.04Å; L155-L259 HydrophobicContact CD2-CD1 4.01Å; L155-L259 HydrophobicContact CD2-CD2 3.81Å; L155-L259 HydrophobicContact CG-CD2 3.68Å; L156-L259 HydrophobicContact CB-CD2 3.9Å; L156-L259 HydrophobicContact CD1-CD2 4.34Å; L159-L259 HydrophobicContact CD1-CD2 3.94Å; M199-L259 HydrophobicContact CE-CD1 4.41Å; D255-L259 PolarHBondContact O-N 3.44Å; A256-L259 PolarHBondContact O-N 3.25Å; L259-A261 VanDerWaalsContact C-N 3.29Å; L259-A261 PolarHBondContact O-N 3.12Å; L259-V262 PolarHBondContact O-N 3.41Å; L259-A263 HydrophobicContact CD1-CB 3.74Å; L259-A263 HydrophobicContact CG-CB 4.44Å; L259-A263 VanDerWaalsContact O-CB 3.3Å; L259-A263 WeakPolarHBondContact O-CB 3.48Å; L259-A263 PolarHBondContact O-N 3.07Å
260	L	87.1	Confident	78.5	Confident	73 Å²	73	55.2 Å²	55.2	38%	0.382	32%	0.316	S	S	.	.	H	α-helix	trans	-57.7	-41.8	176.2	-83.3	168.6	0	0	0	112.4	L156 A256 L257 L258 K264 P265	L156-L260 HydrophobicContact CD1-CD1 4.09Å; L156-L260 HydrophobicContact CD1-CD2 4.31Å; L156-L260 HydrophobicContact CD1-CG 3.77Å; L156-L260 HydrophobicContact CD2-CD1 4.41Å; L156-L260 HydrophobicContact CD2-CD2 3.47Å; L156-L260 VanDerWaalsContact CD2-CD2 3.47Å; L156-L260 HydrophobicContact CD2-CG 3.9Å; A256-L260 PolarHBondContact O-N 2.92Å; L257-L260 PolarHBondContact O-N 3.48Å; L258-L260 PolarHBondContact O-N 3.35Å; L260-K264 PolarHBondContact O-N 3.5Å; L260-P265 HydrophobicContact CD2-CG 3.78Å
261	A	84.2	Confident	76.4	Confident	52 Å²	52	62 Å²	62	43%	0.43	33%	0.333	S	S	.	.	H	α-helix	trans	-69.4	-39	179.8	0	0	0	0	0	112.9	L257 L258 L259	L257-A261 PolarHBondContact O-N 3.46Å; L258-A261 PolarHBondContact O-N 2.99Å; L259-A261 VanDerWaalsContact C-N 3.29Å; L259-A261 PolarHBondContact O-N 3.12Å
262	V	81.4	Confident	74.4	Confident	8 Å²	8	62.6 Å²	62.6	5%	0.048	34%	0.344	C	S	.	.	H	α-helix	trans	-87.4	-46.6	-173	178.8	0	0	0	0	112.5	L25 Q31 L34 L35 I38 L258 L259	L25-V262 HydrophobicContact CD2-CB 4.3Å; L25-V262 HydrophobicContact CD2-CG1 4.49Å; L25-V262 HydrophobicContact CD2-CG2 3.53Å; Q31-V262 HydrophobicContact CG-CG1 3.74Å; Q31-V262 PolarHBondContact NE2-O 3.04Å; L34-V262 HydrophobicContact CB-CG1 4.23Å; L34-V262 HydrophobicContact CB-CG2 4.27Å; L34-V262 HydrophobicContact CD1-CG2 4.38Å; L35-V262 HydrophobicContact CD2-CB 4.43Å; L35-V262 HydrophobicContact CD2-CG1 3.77Å; L35-V262 HydrophobicContact CG-CG1 3.93Å; I38-V262 HydrophobicContact CD1-CB 4.16Å; I38-V262 HydrophobicContact CD1-CG2 4.11Å; L258-V262 HydrophobicContact CD1-CG2 4.04Å; L258-V262 HydrophobicContact CG-CG2 4.29Å; L258-V262 WeakPolarHBondContact O-CB 3.26Å; L258-V262 WeakPolarHBondContact O-CG2 3.31Å; L258-V262 PolarHBondContact O-N 2.94Å; L259-V262 PolarHBondContact O-N 3.41Å
263	A	69.3	Low	72.5	Confident	15 Å²	15	69.2 Å²	69.2	12%	0.124	37%	0.369	C	S	.	.	H	α-helix	trans	-87.8	-24.6	-170.2	0	0	0	0	0	113.4	L35 D152 L259	L35-A263 HydrophobicContact CD2-CB 4.14Å; D152-A263 HydrophobicContact CB-CB 3.93Å; L259-A263 HydrophobicContact CD1-CB 3.74Å; L259-A263 HydrophobicContact CG-CB 4.44Å; L259-A263 VanDerWaalsContact O-CB 3.3Å; L259-A263 WeakPolarHBondContact O-CB 3.48Å; L259-A263 PolarHBondContact O-N 3.07Å
264	K	69.3	Low	70.4	Confident	138 Å²	138	66 Å²	66	60%	0.6	36%	0.36	S	S	*	.			trans	43.7	64.3	-172.4	-64.5	-175.9	-179.8	-179.9	0	111.7	L260 F266 S267	L260-K264 PolarHBondContact O-N 3.5Å; K264-F266 PolarHBondContact O-N 3.43Å; K264-S267 WeakPolarHBondContact O-CB 3.3Å; K264-S267 PolarHBondContact O-N 3.11Å
265	P	59.3	Low	68.3	Low	7 Å²	7	66.6 Å²	66.6	5%	0.045	37%	0.369	C	S	.	.	T	Hydrogen-bonded Turn	trans	-56.2	-18.5	-168.2	16.7	-29.4	0	0	0	115.3	D152 V153 L156 L260	D152-P265 HydrophobicContact CB-CB 3.89Å; V153-P265 HydrophobicContact CG2-CB 3.72Å; V153-P265 WeakPolarHBondContact CG2-O 3.13Å; L156-P265 HydrophobicContact CD2-CG 4.08Å; L260-P265 HydrophobicContact CD2-CG 3.78Å
266	F	58.8	Low	66.5	Low	147 Å²	147	70.7 Å²	70.7	65%	0.645	39%	0.391	S	S	*	.	T	Hydrogen-bonded Turn	trans	-96.6	6.6	-178.7	-60.8	-73.9	0	0	0	115.5	K264 R271	K264-F266 PolarHBondContact O-N 3.43Å; F266-R271 PolarHBondContact O-NH2 3.47Å
267	S	56	Low	64.5	Low	57 Å²	57	73.8 Å²	73.8	40%	0.399	41%	0.41	S	S	.	.			trans	-65.8	146.3	-178.6	-173.4	0	0	0	0	112.9	K264 A269 A270	K264-S267 WeakPolarHBondContact O-CB 3.3Å; K264-S267 PolarHBondContact O-N 3.11Å; S267-A269 PolarHBondContact O-N 2.9Å; S267-A270 VanDerWaalsContact O-CB 3.28Å; S267-A270 WeakPolarHBondContact O-CB 3.47Å; S267-A270 PolarHBondContact O-N 3.42Å
268	A	49.9	Very low	62.9	Low	74 Å²	74	75.1 Å²	75.1	61%	0.612	42%	0.421	S	S	*	.	H	α-helix	trans	-59.3	-28.2	177.6	0	0	0	0	0	113.2	A270 R271 A272	A268-A270 VanDerWaalsContact C-N 3.32Å; A268-A270 PolarHBondContact O-N 2.76Å; A268-R271 PolarHBondContact O-N 3.15Å; A268-A272 PolarHBondContact O-N 2.92Å
269	A	52	Low	61.4	Low	68 Å²	68	72.6 Å²	72.6	56%	0.562	41%	0.412	S	S	*	.	H	α-helix	trans	-70	-26.2	175.2	0	0	0	0	0	113.5	S267	S267-A269 PolarHBondContact O-N 2.9Å
270	A	52.9	Low	60.1	Low	13 Å²	13	74.2 Å²	74.2	11%	0.107	42%	0.421	C	S	.	.	H	α-helix	trans	-69.8	-46.7	174.2	0	0	0	0	0	109.6	S150 S267 A268 A272 R273	S150-A270 WeakPolarHBondContact OG-CA 3.43Å; S150-A270 WeakPolarHBondContact OG-CB 3.21Å; S150-A270 PolarHBondContact OG-O 3.4Å; S267-A270 VanDerWaalsContact O-CB 3.28Å; S267-A270 WeakPolarHBondContact O-CB 3.47Å; S267-A270 PolarHBondContact O-N 3.42Å; A268-A270 VanDerWaalsContact C-N 3.32Å; A268-A270 PolarHBondContact O-N 2.76Å; A270-A272 VanDerWaalsContact C-N 3.29Å; A270-A272 PolarHBondContact O-N 2.99Å; A270-R273 PolarHBondContact O-N 3.12Å
271	R	50.9	Low	59.2	Low	182 Å²	182	73.3 Å²	73.3	69%	0.687	42%	0.42	S	S	*	.	H	α-helix	trans	-59.3	-31.7	177	-84.4	-179.4	-97	173.3	-7.7	114.5	F266 A268 R273	F266-R271 PolarHBondContact O-NH2 3.47Å; A268-R271 PolarHBondContact O-N 3.15Å; R271-R273 VanDerWaalsContact C-N 3.29Å; R271-R273 PolarHBondContact O-N 3.35Å
272	A	51.9	Low	58.6	Low	73 Å²	73	72.1 Å²	72.1	60%	0.603	41%	0.406	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.6	-18.4	177.5	0	0	0	0	0	113.9	A268 A270	A268-A272 PolarHBondContact O-N 2.92Å; A270-A272 VanDerWaalsContact C-N 3.29Å; A270-A272 PolarHBondContact O-N 2.99Å
273	R	53.8	Low	58.3	Low	139 Å²	139	77.3 Å²	77.3	53%	0.525	43%	0.429	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.6	-4.6	-179.1	-77.7	-179.5	167.2	-151.5	-8.1	114.6	D202 A270 R271 N275 L276	D202-R273 IonicContact OD2-NH1 3.08Å; D202-R273 PolarHBondContact OD2-NH1 3.02Å; D202-R273 VanDerWaalsContact OD2-NH1 3.08Å; A270-R273 PolarHBondContact O-N 3.12Å; R271-R273 VanDerWaalsContact C-N 3.29Å; R271-R273 PolarHBondContact O-N 3.35Å; R273-N275 PolarHBondContact O-N 3.44Å; R273-L276 WeakPolarHBondContact O-CD1 3.26Å
274	A	52.2	Low	58.6	Low	29 Å²	29	84.3 Å²	84.3	24%	0.24	45%	0.453	C	S	.	.	T	Hydrogen-bonded Turn	trans	-68.8	7.5	177.1	0	0	0	0	0	114.7	R148	R148-A274 WeakPolarHBondContact O-CB 3.37Å
275	N	50	Low	59	Low	146 Å²	146	77.7 Å²	77.7	78%	0.781	42%	0.424	S	S	*	.	T	Hydrogen-bonded Turn	trans	-112.2	22.3	-177.7	-70.8	-26.5	0	0	0	112.7	R273	R273-N275 PolarHBondContact O-N 3.44Å
276	L	55.6	Low	59.9	Low	94 Å²	94	81.1 Å²	81.1	49%	0.492	44%	0.44	S	S	.	.	S	Bend	trans	-66.9	149.9	170.7	-98.4	89.6	0	0	0	110.7	R273 V278	R273-L276 WeakPolarHBondContact O-CD1 3.26Å; L276-V278 PolarHBondContact O-N 3.12Å
277	P	50.1	Low	60.9	Low	77 Å²	77	80.6 Å²	80.6	50%	0.5	44%	0.444	S	S	.	.	P	Polyproline II helix	trans	-61.7	129.6	-175.4	18.5	-25.6	0	0	0	111.1	G279 R482	P277-G279 PolarHBondContact O-N 2.68Å; P277-R482 VanDerWaalsContact CG-NH2 3.27Å
278	V	57.5	Low	62.3	Low	120 Å²	120	78.8 Å²	78.8	73%	0.727	43%	0.429	S	S	*	.	P	Polyproline II helix	trans	-60.5	117.7	176.5	-177.3	0	0	0	0	108.3	L276	L276-V278 PolarHBondContact O-N 3.12Å
279	G	58.5	Low	64	Low	13 Å²	13	79.3 Å²	79.3	13%	0.134	43%	0.427	C	S	.	.	P	Polyproline II helix	trans	-61.6	166.4	174	0	0	0	0	0	111.7	P277	P277-G279 PolarHBondContact O-N 2.68Å
280	T	62.2	Low	65.6	Low	33 Å²	33	79.5 Å²	79.5	20%	0.202	41%	0.413	C	S	.	.	P	Polyproline II helix	trans	-57.4	137.3	171.4	43.3	0	0	0	0	110	I282 L285 H413 V414	T280-I282 PolarHBondContact O-N 3.11Å; T280-L285 WeakPolarHBondContact O-CD1 3.47Å; T280-L285 WeakPolarHBondContact OG1-CD1 3.46Å; T280-H413 HydrophobicContact CG2-CB 4.23Å; T280-V414 PolarHBondContact OG1-O 3.25Å
281	P	67.2	Low	67.1	Low	55 Å²	55	78.9 Å²	78.9	36%	0.357	41%	0.408	S	S	.	.	P	Polyproline II helix	trans	-68.1	138	-173.4	28.1	-35.8	0	0	0	110.9	H283 R284 L285	P281-H283 VanDerWaalsContact CB-CE1 3.5Å; P281-H283 WeakPolarHBondContact CB-CE1 3.37Å; P281-H283 VanDerWaalsContact CG-CE1 3.44Å; P281-H283 WeakPolarHBondContact CG-CE1 3.36Å; P281-H283 PolarHBondContact O-N 3.39Å; P281-R284 HydrophobicContact CG-CB 4.39Å; P281-R284 HydrophobicContact CG-CG 4.16Å; P281-R284 WeakPolarHBondContact O-CB 3.25Å; P281-R284 PolarHBondContact O-N 3.06Å; P281-L285 VanDerWaalsContact O-CD1 3.26Å; P281-L285 WeakPolarHBondContact O-CD1 3.41Å
282	I	72.8	Confident	68.9	Low	26 Å²	26	72.2 Å²	72.2	13%	0.133	39%	0.392	C	S	.	.	H	α-helix	trans	-49.8	-39.2	-171.9	-63.7	167.5	0	0	0	112.8	T280 R284 L285 M286 A422 I423 I426	T280-I282 PolarHBondContact O-N 3.11Å; I282-R284 VanDerWaalsContact C-N 3.26Å; I282-R284 PolarHBondContact O-N 3.26Å; I282-L285 PolarHBondContact O-N 3.1Å; I282-L285 VanDerWaalsContact O-N 3.08Å; I282-M286 HydrophobicContact CG2-CG 4.2Å; I282-M286 HydrophobicContact CG2-SD 4.14Å; I282-M286 PolarHBondContact O-N 3.19Å; I282-A422 HydrophobicContact CD1-CB 4.04Å; I282-I423 HydrophobicContact CG2-CG1 4.02Å; I282-I426 HydrophobicContact CG2-CD1 4.18Å
283	H	74	Confident	70.7	Confident	117 Å²	117	69.5 Å²	69.5	54%	0.542	37%	0.368	S	S	.	.	H	α-helix	trans	-60.3	-33.4	179.1	71.3	-91	0	0	0	113.2	P281 L287	P281-H283 VanDerWaalsContact CB-CE1 3.5Å; P281-H283 WeakPolarHBondContact CB-CE1 3.37Å; P281-H283 VanDerWaalsContact CG-CE1 3.44Å; P281-H283 WeakPolarHBondContact CG-CE1 3.36Å; P281-H283 PolarHBondContact O-N 3.39Å; H283-L287 WeakPolarHBondContact O-CD1 3.45Å; H283-L287 VanDerWaalsContact O-CG 3.25Å; H283-L287 WeakPolarHBondContact O-CG 3.36Å; H283-L287 PolarHBondContact O-N 2.83Å
284	R	76.1	Confident	72.4	Confident	162 Å²	162	62.9 Å²	62.9	61%	0.611	34%	0.343	S	S	*	.	H	α-helix	trans	-73.4	-34.5	175.3	-77.9	-168.3	178.5	176	-1.1	112.2	P281 I282 L287	P281-R284 HydrophobicContact CG-CB 4.39Å; P281-R284 HydrophobicContact CG-CG 4.16Å; P281-R284 WeakPolarHBondContact O-CB 3.25Å; P281-R284 PolarHBondContact O-N 3.06Å; I282-R284 VanDerWaalsContact C-N 3.26Å; I282-R284 PolarHBondContact O-N 3.26Å; R284-L287 PolarHBondContact O-N 2.86Å
285	L	77.9	Confident	74.2	Confident	0 Å²	0	61.9 Å²	61.9	0%	0	34%	0.335	C	S	.	.	H	α-helix	trans	-67	-43.6	175.1	-74.2	72.5	0	0	0	110.5	T280 P281 I282 L287 D288 I291 V409 I423	T280-L285 WeakPolarHBondContact O-CD1 3.47Å; T280-L285 WeakPolarHBondContact OG1-CD1 3.46Å; P281-L285 VanDerWaalsContact O-CD1 3.26Å; P281-L285 WeakPolarHBondContact O-CD1 3.41Å; I282-L285 PolarHBondContact O-N 3.1Å; I282-L285 VanDerWaalsContact O-N 3.08Å; L285-L287 PolarHBondContact O-N 2.96Å; L285-D288 WeakPolarHBondContact O-CB 3.45Å; L285-D288 PolarHBondContact O-N 3.21Å; L285-I291 HydrophobicContact CB-CD1 4.09Å; L285-I291 HydrophobicContact CG-CD1 4.47Å; L285-I291 WeakPolarHBondContact O-CB 3.44Å; L285-I291 WeakPolarHBondContact O-CD1 3.18Å; L285-I291 WeakPolarHBondContact O-CG2 3.15Å; L285-V409 HydrophobicContact CD2-CG1 3.61Å; L285-V409 HydrophobicContact CD2-CG2 4Å; L285-I423 HydrophobicContact CB-CD1 3.55Å; L285-I423 HydrophobicContact CD2-CD1 3.73Å; L285-I423 HydrophobicContact CG-CD1 4.31Å
286	M	76.9	Confident	76.2	Confident	79 Å²	79	55.7 Å²	55.7	39%	0.389	31%	0.305	S	S	.	.	H	α-helix	trans	-65.5	-22.9	178.5	-69.4	-172.6	74.1	0	0	113.6	I282 D288 I423 I426	I282-M286 HydrophobicContact CG2-CG 4.2Å; I282-M286 HydrophobicContact CG2-SD 4.14Å; I282-M286 PolarHBondContact O-N 3.19Å; M286-D288 VanDerWaalsContact C-N 3.32Å; M286-I423 HydrophobicContact CG-CG1 4.18Å; M286-I426 HydrophobicContact CE-CG2 4.01Å; M286-I426 HydrophobicContact SD-CD1 4.39Å; M286-I426 HydrophobicContact SD-CG2 4.43Å
287	L	81.3	Confident	77.9	Confident	136 Å²	136	51.2 Å²	51.2	71%	0.712	28%	0.282	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.7	-11.9	174.5	-74.5	165.3	0	0	0	113.1	H283 R284 L285	H283-L287 WeakPolarHBondContact O-CD1 3.45Å; H283-L287 VanDerWaalsContact O-CG 3.25Å; H283-L287 WeakPolarHBondContact O-CG 3.36Å; H283-L287 PolarHBondContact O-N 2.83Å; R284-L287 PolarHBondContact O-N 2.86Å; L285-L287 PolarHBondContact O-N 2.96Å
288	D	84.5	Confident	79.9	Confident	18 Å²	18	47.6 Å²	47.6	10%	0.096	26%	0.258	C	S	.	.	S	Bend	trans	-70.1	124.9	173.4	-172.9	-51.3	0	0	0	109.4	L285 M286 Y290 I291 A292 R412 H413	L285-D288 WeakPolarHBondContact O-CB 3.45Å; L285-D288 PolarHBondContact O-N 3.21Å; M286-D288 VanDerWaalsContact C-N 3.32Å; D288-Y290 PolarHBondContact O-N 3.13Å; D288-Y290 PolarHBondContact OD1-N 2.87Å; D288-I291 HydrophobicContact CB-CB 4.05Å; D288-I291 HydrophobicContact CB-CD1 3.8Å; D288-I291 HydrophobicContact CB-CG1 3.91Å; D288-I291 PolarHBondContact O-N 3.26Å; D288-A292 WeakPolarHBondContact O-CB 3.39Å; D288-A292 PolarHBondContact O-N 3.5Å; D288-R412 VanDerWaalsContact CG-NH1 3.33Å; D288-R412 IonicContact OD1-CZ 3.19Å; D288-R412 IonicContact OD1-NH1 3.3Å; D288-R412 PolarHBondContact OD1-NH1 3.09Å; D288-R412 WeakPolarHBondContact OD2-CD 3.39Å; D288-R412 IonicContact OD2-CZ 3.6Å; D288-R412 IonicContact OD2-NE 2.92Å; D288-R412 IonicContact OD2-NH1 3.99Å; D288-R412 PolarHBondContact OD2-NH1 3.13Å; D288-H413 IonicContact OD2-NE2 3.15Å
289	P	85.4	Confident	81.5	Confident	86 Å²	86	42.9 Å²	42.9	56%	0.558	23%	0.23	S	C	*	.	H	α-helix	trans	-59.9	-33.1	-174.2	21.5	-32.1	0	0	0	113.3	V293	P289-V293 WeakPolarHBondContact O-CG2 3.23Å; P289-V293 PolarHBondContact O-N 3.27Å
290	Y	85	Confident	83.1	Confident	72 Å²	72	43.1 Å²	43.1	28%	0.282	23%	0.229	S	C	.	.	H	α-helix	trans	-77.2	-37.6	-179.1	-67.2	-101.3	0	0	0	111	D288 A292 V293 V294 R412 L468 L469 V472	D288-Y290 PolarHBondContact O-N 3.13Å; D288-Y290 PolarHBondContact OD1-N 2.87Å; Y290-A292 VanDerWaalsContact C-N 3.33Å; Y290-V293 PolarHBondContact O-N 3.39Å; Y290-V294 WeakPolarHBondContact O-CG2 3.29Å; Y290-V294 PolarHBondContact O-N 3.46Å; Y290-R412 VanDerWaalsContact CD2-CZ 3.45Å; Y290-L468 WeakPolarHBondContact CE1-O 3.31Å; Y290-L469 HydrophobicContact CD1-CD2 4.07Å; Y290-V472 HydrophobicContact CD1-CG2 3.96Å; Y290-V472 HydrophobicContact CE1-CG2 4.42Å
291	I	86.1	Confident	84.6	Confident	0 Å²	0	41.6 Å²	41.6	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-66.8	-41.9	175.7	-63.2	177.8	0	0	0	108.8	L285 D288 V293 V294 A295 L405 L408 V409 I423	L285-I291 HydrophobicContact CB-CD1 4.09Å; L285-I291 HydrophobicContact CG-CD1 4.47Å; L285-I291 WeakPolarHBondContact O-CB 3.44Å; L285-I291 WeakPolarHBondContact O-CD1 3.18Å; L285-I291 WeakPolarHBondContact O-CG2 3.15Å; D288-I291 HydrophobicContact CB-CB 4.05Å; D288-I291 HydrophobicContact CB-CD1 3.8Å; D288-I291 HydrophobicContact CB-CG1 3.91Å; D288-I291 PolarHBondContact O-N 3.26Å; I291-V293 PolarHBondContact O-N 3.12Å; I291-V294 PolarHBondContact O-N 2.96Å; I291-A295 VanDerWaalsContact O-CB 3.3Å; I291-A295 WeakPolarHBondContact O-CB 3.32Å; I291-A295 PolarHBondContact O-N 3.13Å; I291-L405 HydrophobicContact CG2-CD1 3.8Å; I291-L408 HydrophobicContact CB-CD2 4.27Å; I291-L408 HydrophobicContact CG1-CD2 3.48Å; I291-L408 VanDerWaalsContact CG1-CD2 3.48Å; I291-L408 HydrophobicContact CG1-CG 3.92Å; I291-L408 VanDerWaalsContact N-CD2 3.35Å; I291-V409 HydrophobicContact CD1-CG2 3.65Å; I291-V409 HydrophobicContact CG1-CG2 4.31Å; I291-I423 HydrophobicContact CG2-CD1 4.02Å; I291-I423 HydrophobicContact CG2-CG2 4.26Å
292	A	87.8	Confident	85.7	Confident	41 Å²	41	39.2 Å²	39.2	34%	0.339	20%	0.203	S	C	.	.	H	α-helix	trans	-61.8	-38.8	176.2	0	0	0	0	0	112.8	D288 Y290 G296	D288-A292 WeakPolarHBondContact O-CB 3.39Å; D288-A292 PolarHBondContact O-N 3.5Å; Y290-A292 VanDerWaalsContact C-N 3.33Å; A292-G296 PolarHBondContact O-N 2.8Å
293	V	90.4	Very high	86.5	Confident	17 Å²	17	40.1 Å²	40.1	10%	0.103	21%	0.208	C	C	.	.	H	α-helix	trans	-63.2	-44.4	174.3	170.9	0	0	0	0	111.3	P289 Y290 I291 G296 A297 Y462 V465 L466 L468 L469	P289-V293 WeakPolarHBondContact O-CG2 3.23Å; P289-V293 PolarHBondContact O-N 3.27Å; Y290-V293 PolarHBondContact O-N 3.39Å; I291-V293 PolarHBondContact O-N 3.12Å; V293-G296 PolarHBondContact O-N 3.3Å; V293-A297 WeakPolarHBondContact O-CB 3.25Å; V293-A297 PolarHBondContact O-N 2.84Å; V293-Y462 PolarHBondContact O-OH 2.71Å; V293-V465 HydrophobicContact CG1-CG1 4.03Å; V293-V465 HydrophobicContact CG2-CG1 4.16Å; V293-L466 HydrophobicContact CG1-CD2 4.35Å; V293-L468 HydrophobicContact CG2-CD1 4.15Å; V293-L469 HydrophobicContact CB-CD2 4.48Å; V293-L469 HydrophobicContact CG1-CD1 4.17Å; V293-L469 HydrophobicContact CG1-CD2 4.33Å; V293-L469 HydrophobicContact CG1-CG 4.09Å
294	V	89.9	Confident	87.3	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-65.4	-47	177.8	178.1	0	0	0	0	110.8	Y290 I291 G296 A297 L298 L401 T404 L405 L469	Y290-V294 WeakPolarHBondContact O-CG2 3.29Å; Y290-V294 PolarHBondContact O-N 3.46Å; I291-V294 PolarHBondContact O-N 2.96Å; V294-G296 VanDerWaalsContact C-N 3.32Å; V294-G296 PolarHBondContact O-N 3.12Å; V294-A297 PolarHBondContact O-N 3.4Å; V294-L298 HydrophobicContact CG1-CD1 4.29Å; V294-L298 WeakPolarHBondContact O-CG 3.49Å; V294-L298 PolarHBondContact O-N 2.98Å; V294-L401 HydrophobicContact CG1-CB 3.98Å; V294-L401 HydrophobicContact CG1-CD1 4.5Å; V294-T404 HydrophobicContact CG2-CG2 4.49Å; V294-L405 HydrophobicContact CB-CD1 4.04Å; V294-L405 HydrophobicContact CG1-CB 3.9Å; V294-L405 HydrophobicContact CG1-CD1 3.88Å; V294-L405 HydrophobicContact CG1-CG 4.37Å; V294-L469 HydrophobicContact CG2-CD1 3.62Å; V294-L469 HydrophobicContact CG2-CD2 3.94Å; V294-L469 HydrophobicContact CG2-CG 4.46Å
295	A	89.9	Confident	87.8	Confident	8 Å²	8	27.9 Å²	27.9	7%	0.066	16%	0.159	C	C	.	.	H	α-helix	trans	-60.6	-40.1	177.5	0	0	0	0	0	112.2	I291 T299 I423 S427	I291-A295 VanDerWaalsContact O-CB 3.3Å; I291-A295 WeakPolarHBondContact O-CB 3.32Å; I291-A295 PolarHBondContact O-N 3.13Å; A295-T299 PolarHBondContact O-N 2.9Å; A295-T299 PolarHBondContact O-OG1 2.8Å; A295-I423 HydrophobicContact CB-CG2 3.94Å; A295-S427 VanDerWaalsContact CA-OG 3.28Å; A295-S427 WeakPolarHBondContact CA-OG 3.44Å; A295-S427 WeakPolarHBondContact CB-OG 3.42Å; A295-S427 WeakPolarHBondContact O-CB 3.39Å; A295-S427 PolarHBondContact O-OG 3.36Å
296	G	91.1	Very high	88.2	Confident	16 Å²	16	27.9 Å²	27.9	17%	0.165	16%	0.159	C	C	.	.	H	α-helix	trans	-70.5	-35.4	176.2	0	0	0	0	0	113	A292 V293 V294 T299 T300 Y462	A292-G296 PolarHBondContact O-N 2.8Å; V293-G296 PolarHBondContact O-N 3.3Å; V294-G296 VanDerWaalsContact C-N 3.32Å; V294-G296 PolarHBondContact O-N 3.12Å; G296-T299 PolarHBondContact O-N 3.38Å; G296-T300 WeakPolarHBondContact O-CB 3.41Å; G296-T300 PolarHBondContact O-N 2.84Å; G296-T300 PolarHBondContact O-OG1 2.94Å; G296-Y462 WeakPolarHBondContact CA-OH 3.29Å
297	A	91.5	Very high	88.6	Confident	0 Å²	0	24.2 Å²	24.2	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-64.9	-44.7	172.2	0	0	0	0	0	111.8	V293 V294 T299 T300 C301 L401 Y462 L466	V293-A297 WeakPolarHBondContact O-CB 3.25Å; V293-A297 PolarHBondContact O-N 2.84Å; V294-A297 PolarHBondContact O-N 3.4Å; A297-T299 VanDerWaalsContact C-N 3.27Å; A297-T299 PolarHBondContact O-N 3.29Å; A297-T300 PolarHBondContact O-N 3.24Å; A297-C301 WeakPolarHBondContact O-CB 3.31Å; A297-C301 PolarHBondContact O-N 2.92Å; A297-C301 PolarHBondContact O-SG 3.33Å; A297-C301 VanDerWaalsContact O-SG 3.38Å; A297-L401 HydrophobicContact CB-CD1 3.43Å; A297-L401 VanDerWaalsContact CB-CD1 3.43Å; A297-Y462 HydrophobicContact CB-CD1 4.11Å; A297-Y462 HydrophobicContact CB-CE1 3.72Å; A297-L466 HydrophobicContact CB-CD2 3.86Å
298	L	91.8	Very high	88.7	Confident	0 Å²	0	17.8 Å²	17.8	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-60.7	-36.5	174.3	-70.1	174.1	0	0	0	112.1	V294 C301 N302 D398 L401 L402 L405 A424 Y428	V294-L298 HydrophobicContact CG1-CD1 4.29Å; V294-L298 WeakPolarHBondContact O-CG 3.49Å; V294-L298 PolarHBondContact O-N 2.98Å; L298-C301 PolarHBondContact O-SG 2.89Å; L298-N302 PolarHBondContact O-ND2 2.86Å; L298-D398 WeakPolarHBondContact CD2-OD1 3.48Å; L298-L401 HydrophobicContact CD2-CB 3.99Å; L298-L401 HydrophobicContact CD2-CD1 4.31Å; L298-L401 HydrophobicContact CG-CB 4.4Å; L298-L401 HydrophobicContact CG-CD1 4.39Å; L298-L402 HydrophobicContact CD1-CD2 4.13Å; L298-L405 HydrophobicContact CD1-CD2 4.42Å; L298-A424 HydrophobicContact CD1-CB 4.15Å; L298-Y428 HydrophobicContact CB-CE1 4.36Å; L298-Y428 HydrophobicContact CD2-CE1 4.31Å
299	T	92.1	Very high	88.4	Confident	22 Å²	22	17 Å²	17	14%	0.135	10%	0.103	C	C	.	.	H	α-helix	trans	-67.7	-50.1	174.4	-50.8	0	0	0	0	110.3	A295 G296 A297 C301 N302 I303 S427 V430 A431	A295-T299 PolarHBondContact O-N 2.9Å; A295-T299 PolarHBondContact O-OG1 2.8Å; G296-T299 PolarHBondContact O-N 3.38Å; A297-T299 VanDerWaalsContact C-N 3.27Å; A297-T299 PolarHBondContact O-N 3.29Å; T299-C301 PolarHBondContact O-N 2.95Å; T299-N302 PolarHBondContact O-N 2.95Å; T299-I303 HydrophobicContact CG2-CD1 4.44Å; T299-I303 WeakPolarHBondContact O-CG1 3.33Å; T299-I303 PolarHBondContact O-N 3.27Å; T299-S427 WeakPolarHBondContact OG1-CB 3.37Å; T299-S427 PolarHBondContact OG1-O 3.24Å; T299-V430 HydrophobicContact CG2-CB 4.08Å; T299-V430 HydrophobicContact CG2-CG1 3.71Å; T299-A431 HydrophobicContact CG2-CB 4.16Å; T299-A431 WeakPolarHBondContact O-CB 3.27Å
300	T	91.6	Very high	87.9	Confident	18 Å²	18	13.5 Å²	13.5	11%	0.11	8%	0.08	C	C	.	.	H	α-helix	trans	-65.7	-38.1	-173.2	-52.4	0	0	0	0	112.3	G296 A297 N302 P304 N459 Y462	G296-T300 WeakPolarHBondContact O-CB 3.41Å; G296-T300 PolarHBondContact O-N 2.84Å; G296-T300 PolarHBondContact O-OG1 2.94Å; A297-T300 PolarHBondContact O-N 3.24Å; T300-N302 VanDerWaalsContact C-N 3.31Å; T300-N302 PolarHBondContact O-N 3.17Å; T300-P304 WeakPolarHBondContact O-CD 3.42Å; T300-N459 PolarHBondContact O-ND2 3.46Å; T300-N459 PolarHBondContact O-OD1 3.17Å; T300-Y462 HydrophobicContact CG2-CG 4.32Å
301	C	92.3	Very high	87.5	Confident	0 Å²	0	11 Å²	11	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-67.7	-30	178.4	70.3	0	0	0	0	113.3	A297 L298 T299 P304 L364 I367 V397 N459	A297-C301 WeakPolarHBondContact O-CB 3.31Å; A297-C301 PolarHBondContact O-N 2.92Å; A297-C301 PolarHBondContact O-SG 3.33Å; A297-C301 VanDerWaalsContact O-SG 3.38Å; L298-C301 PolarHBondContact O-SG 2.89Å; T299-C301 PolarHBondContact O-N 2.95Å; C301-P304 WeakPolarHBondContact O-CD 3.35Å; C301-L364 HydrophobicContact CB-CD2 3.72Å; C301-I367 HydrophobicContact CB-CD1 3.53Å; C301-V397 HydrophobicContact CB-CB 4.13Å; C301-V397 HydrophobicContact CB-CG1 3.86Å; C301-V397 HydrophobicContact CB-CG2 4.11Å; C301-N459 WeakPolarHBondContact CA-OD1 3.38Å
302	N	90.8	Very high	87.2	Confident	5 Å²	5	11 Å²	11	3%	0.027	7%	0.072	C	C	.	.	H	α-helix	trans	-89.1	-16.9	-178.5	-79.3	-75.3	0	0	0	113.8	L298 T299 T300 L305 A306 Y428 A431	L298-N302 PolarHBondContact O-ND2 2.86Å; T299-N302 PolarHBondContact O-N 2.95Å; T300-N302 VanDerWaalsContact C-N 3.31Å; T300-N302 PolarHBondContact O-N 3.17Å; N302-L305 PolarHBondContact O-N 3.28Å; N302-A306 WeakPolarHBondContact O-CB 3.39Å; N302-A306 PolarHBondContact O-N 3.42Å; N302-Y428 VanDerWaalsContact ND2-CD1 3.32Å; N302-Y428 WeakPolarHBondContact ND2-CD1 3.43Å; N302-Y428 WeakPolarHBondContact ND2-CE1 3.27Å; N302-A431 HydrophobicContact CB-CB 3.78Å
303	I	90.3	Very high	86.7	Confident	46 Å²	46	9.5 Å²	9.5	24%	0.236	6%	0.06	C	C	.	.	H	α-helix	trans	-54.7	-48.4	176.9	-76	168.1	0	0	0	112.7	T299 L305 A306 F307 A431 M455	T299-I303 HydrophobicContact CG2-CD1 4.44Å; T299-I303 WeakPolarHBondContact O-CG1 3.33Å; T299-I303 PolarHBondContact O-N 3.27Å; I303-L305 VanDerWaalsContact C-N 3.3Å; I303-L305 PolarHBondContact O-N 3.05Å; I303-A306 PolarHBondContact O-N 3.27Å; I303-F307 WeakPolarHBondContact O-CB 3.28Å; I303-F307 PolarHBondContact O-N 2.84Å; I303-A431 HydrophobicContact CG1-CB 4.03Å; I303-M455 HydrophobicContact CG2-CB 4.48Å; I303-M455 HydrophobicContact CG2-CG 3.94Å; I303-M455 HydrophobicContact CG2-SD 3.78Å
304	P	89.9	Confident	86	Confident	0 Å²	0	10.1 Å²	10.1	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-59.6	-39.6	178.5	-26.5	35.5	0	0	0	113.4	T300 C301 F307 L308 I367 S371 L390 M455 N459	T300-P304 WeakPolarHBondContact O-CD 3.42Å; C301-P304 WeakPolarHBondContact O-CD 3.35Å; P304-F307 PolarHBondContact O-N 3.48Å; P304-L308 VanDerWaalsContact O-CB 3.28Å; P304-L308 WeakPolarHBondContact O-CB 3.3Å; P304-L308 WeakPolarHBondContact O-CG 3.36Å; P304-L308 PolarHBondContact O-N 3.45Å; P304-I367 HydrophobicContact CB-CG2 4.26Å; P304-I367 HydrophobicContact CG-CG2 3.74Å; P304-S371 WeakPolarHBondContact CB-OG 3.39Å; P304-L390 HydrophobicContact CB-CD1 3.98Å; P304-M455 HydrophobicContact CG-CB 4.29Å; P304-N459 WeakPolarHBondContact CG-ND2 3.3Å
305	L	87.5	Confident	85.3	Confident	21 Å²	21	12 Å²	12	11%	0.11	7%	0.071	C	C	.	.	H	α-helix	trans	-66.6	-50.9	178.4	-178.5	61.4	0	0	0	110.7	N302 I303 F307 L308 E309 W331 L390 I394 Y432	N302-L305 PolarHBondContact O-N 3.28Å; I303-L305 VanDerWaalsContact C-N 3.3Å; I303-L305 PolarHBondContact O-N 3.05Å; L305-F307 PolarHBondContact O-N 3.42Å; L305-L308 PolarHBondContact O-N 2.97Å; L305-L308 VanDerWaalsContact O-N 3.11Å; L305-E309 HydrophobicContact CD1-CG 4.38Å; L305-E309 VanDerWaalsContact CG-OE1 3.28Å; L305-E309 WeakPolarHBondContact CG-OE1 3.25Å; L305-E309 WeakPolarHBondContact O-CG 3.36Å; L305-E309 PolarHBondContact O-N 3.26Å; L305-W331 HydrophobicContact CD1-CH2 3.54Å; L305-W331 HydrophobicContact CD1-CZ3 3.5Å; L305-W331 VanDerWaalsContact CD1-CZ3 3.5Å; L305-L390 HydrophobicContact CB-CD2 4.26Å; L305-L390 HydrophobicContact CD1-CD2 4.13Å; L305-I394 HydrophobicContact CB-CD1 3.63Å; L305-I394 HydrophobicContact CD2-CD1 3.73Å; L305-I394 HydrophobicContact CG-CD1 4.15Å; L305-Y432 WeakPolarHBondContact CD2-OH 3.33Å
306	A	86.4	Confident	84.7	Confident	0 Å²	0	11.7 Å²	11.7	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-56.6	-32	176.4	0	0	0	0	0	113.9	N302 I303 P310 A431 Y432	N302-A306 WeakPolarHBondContact O-CB 3.39Å; N302-A306 PolarHBondContact O-N 3.42Å; I303-A306 PolarHBondContact O-N 3.27Å; A306-P310 VanDerWaalsContact O-CD 3.26Å; A306-P310 WeakPolarHBondContact O-CD 3.18Å; A306-A431 WeakPolarHBondContact CB-O 3.43Å; A306-Y432 HydrophobicContact CB-CD1 3.34Å; A306-Y432 HydrophobicContact CB-CE1 3.74Å; A306-Y432 HydrophobicContact CB-CG 4.12Å
307	F	84.8	Confident	83.9	Confident	2 Å²	2	16 Å²	16	1%	0.009	8%	0.082	C	C	.	.	H	α-helix	trans	-78.4	-46.9	174.9	167.6	-92.1	0	0	0	112.4	I303 P304 L305 E309 P310 T311 A439 V443 F448 L451 M455	I303-F307 WeakPolarHBondContact O-CB 3.28Å; I303-F307 PolarHBondContact O-N 2.84Å; P304-F307 PolarHBondContact O-N 3.48Å; L305-F307 PolarHBondContact O-N 3.42Å; F307-E309 VanDerWaalsContact C-N 3.34Å; F307-E309 PolarHBondContact O-N 3.14Å; F307-P310 WeakPolarHBondContact O-CD 3.14Å; F307-T311 HydrophobicContact CD2-CG2 4.41Å; F307-T311 HydrophobicContact CE2-CG2 3.76Å; F307-T311 HydrophobicContact CZ-CG2 3.9Å; F307-T311 WeakPolarHBondContact O-CG2 3.39Å; F307-T311 PolarHBondContact O-OG1 3.41Å; F307-A439 HydrophobicContact CD2-CB 3.28Å; F307-A439 HydrophobicContact CE2-CB 3.37Å; F307-A439 HydrophobicContact CG-CB 4.42Å; F307-V443 HydrophobicContact CE2-CG2 3.67Å; F307-V443 HydrophobicContact CZ-CG2 3.72Å; F307-F448 HydrophobicContact CE1-CD2 4.02Å; F307-F448 AromaticContact CE1-CE2 3.61Å; F307-F448 HydrophobicContact CE1-CE2 3.61Å; F307-F448 HydrophobicContact CE1-CZ 4.42Å; F307-F448 AromaticContact CZ-CD2 3.82Å; F307-F448 HydrophobicContact CZ-CD2 3.82Å; F307-F448 AromaticContact CZ-CE2 3.87Å; F307-F448 HydrophobicContact CZ-CE2 3.87Å; F307-L451 HydrophobicContact CD2-CD2 3.7Å; F307-L451 HydrophobicContact CD2-CG 4.13Å; F307-L451 HydrophobicContact CE2-CD2 3Å; F307-L451 HydrophobicContact CE2-CG 3.71Å; F307-L451 HydrophobicContact CZ-CB 4.49Å; F307-L451 HydrophobicContact CZ-CD2 3.47Å; F307-L451 VanDerWaalsContact CZ-CD2 3.47Å; F307-L451 HydrophobicContact CZ-CG 3.88Å; F307-M455 HydrophobicContact CB-CE 3.79Å; F307-M455 HydrophobicContact CB-SD 3.43Å; F307-M455 WeakPolarHBondContact CB-SD 3.12Å; F307-M455 HydrophobicContact CD1-CE 3.04Å; F307-M455 HydrophobicContact CD1-SD 3.93Å; F307-M455 HydrophobicContact CD2-CE 4.07Å; F307-M455 HydrophobicContact CD2-SD 4.22Å; F307-M455 HydrophobicContact CE1-CE 3.58Å; F307-M455 HydrophobicContact CG-CE 3.32Å; F307-M455 HydrophobicContact CG-SD 3.56Å; F307-M455 VanDerWaalsContact CG-SD 3.56Å; F307-M455 HydrophobicContact CZ-CE 4.34Å
308	L	83.2	Confident	82.9	Confident	1 Å²	1	21.8 Å²	21.8	1%	0.005	11%	0.109	C	C	.	.	H	α-helix	trans	-67.8	-36	-174.1	-77.2	172.8	0	0	0	111.5	P304 L305 T311 I312 V374 L387 L390 F448	P304-L308 VanDerWaalsContact O-CB 3.28Å; P304-L308 WeakPolarHBondContact O-CB 3.3Å; P304-L308 WeakPolarHBondContact O-CG 3.36Å; P304-L308 PolarHBondContact O-N 3.45Å; L305-L308 PolarHBondContact O-N 2.97Å; L305-L308 VanDerWaalsContact O-N 3.11Å; L308-T311 WeakPolarHBondContact CA-OG1 3.44Å; L308-T311 PolarHBondContact O-N 3.47Å; L308-T311 PolarHBondContact O-OG1 2.88Å; L308-I312 WeakPolarHBondContact O-CA 3.23Å; L308-I312 WeakPolarHBondContact O-CB 3.33Å; L308-I312 WeakPolarHBondContact O-CG2 3.45Å; L308-I312 PolarHBondContact O-N 3.39Å; L308-V374 HydrophobicContact CD1-CG2 4.19Å; L308-V374 HydrophobicContact CD2-CG1 3.9Å; L308-L387 HydrophobicContact CD1-CD2 4.39Å; L308-L390 HydrophobicContact CD1-CD1 3.43Å; L308-L390 VanDerWaalsContact CD1-CD1 3.43Å; L308-F448 HydrophobicContact CD2-CE2 4.23Å; L308-F448 HydrophobicContact CD2-CZ 3.87Å
309	E	79.1	Confident	82	Confident	2 Å²	2	25.6 Å²	25.6	1%	0.009	13%	0.132	C	C	.	.	H	α-helix	trans	-48.9	-61.8	179.7	-80.2	165.8	-152	0	0	114.4	Y50 M51 V54 L305 F307 T311 W331	Y50-E309 WeakPolarHBondContact CE1-OE2 3.42Å; M51-E309 HydrophobicContact CE-CG 4.36Å; M51-E309 WeakPolarHBondContact CE-OE1 3.37Å; M51-E309 HydrophobicContact SD-CG 3.97Å; V54-E309 WeakPolarHBondContact CG1-O 3.32Å; V54-E309 HydrophobicContact CG2-CB 4.2Å; L305-E309 HydrophobicContact CD1-CG 4.38Å; L305-E309 VanDerWaalsContact CG-OE1 3.28Å; L305-E309 WeakPolarHBondContact CG-OE1 3.25Å; L305-E309 WeakPolarHBondContact O-CG 3.36Å; L305-E309 PolarHBondContact O-N 3.26Å; F307-E309 VanDerWaalsContact C-N 3.34Å; F307-E309 PolarHBondContact O-N 3.14Å; E309-T311 VanDerWaalsContact C-N 3.3Å; E309-T311 PolarHBondContact O-N 3.04Å; E309-W331 HydrophobicContact CG-CH2 4.44Å; E309-W331 HydrophobicContact CG-CZ2 4.29Å
310	P	74.6	Confident	81.2	Confident	12 Å²	12	26.7 Å²	26.7	8%	0.078	14%	0.136	C	C	.	.	H	α-helix	trans	-72.2	-22.5	-178.5	28.4	-36.4	0	0	0	113.5	F128 A306 F307 P436	F128-P310 HydrophobicContact CD2-CB 4.06Å; F128-P310 HydrophobicContact CE2-CB 4.3Å; A306-P310 VanDerWaalsContact O-CD 3.26Å; A306-P310 WeakPolarHBondContact O-CD 3.18Å; F307-P310 WeakPolarHBondContact O-CD 3.14Å; P310-P436 HydrophobicContact CG-CB 4.28Å; P310-P436 HydrophobicContact CG-CG 4.36Å
311	T	77.4	Confident	80.2	Confident	19 Å²	19	30.1 Å²	30.1	12%	0.117	17%	0.166	C	C	.	.	H	α-helix	trans	-96	-29.6	-171.6	57.1	0	0	0	0	113.6	F307 L308 E309 A313 T314 W315 A439 V443	F307-T311 HydrophobicContact CD2-CG2 4.41Å; F307-T311 HydrophobicContact CE2-CG2 3.76Å; F307-T311 HydrophobicContact CZ-CG2 3.9Å; F307-T311 WeakPolarHBondContact O-CG2 3.39Å; F307-T311 PolarHBondContact O-OG1 3.41Å; L308-T311 WeakPolarHBondContact CA-OG1 3.44Å; L308-T311 PolarHBondContact O-N 3.47Å; L308-T311 PolarHBondContact O-OG1 2.88Å; E309-T311 VanDerWaalsContact C-N 3.3Å; E309-T311 PolarHBondContact O-N 3.04Å; T311-A313 PolarHBondContact O-N 3.18Å; T311-T314 PolarHBondContact O-N 3.15Å; T311-W315 VanDerWaalsContact O-CB 3.3Å; T311-W315 WeakPolarHBondContact O-CB 3.3Å; T311-W315 PolarHBondContact O-N 3.12Å; T311-A439 HydrophobicContact CG2-CB 3.76Å; T311-V443 HydrophobicContact CG2-CG2 4.23Å
312	I	79.8	Confident	79.2	Confident	2 Å²	2	30.7 Å²	30.7	1%	0.01	17%	0.171	C	C	.	.	H	α-helix	trans	-67.2	-37.6	-173.3	-160.7	162.3	0	0	0	111.9	L308 W315 M316 W331 L383 L387	L308-I312 WeakPolarHBondContact O-CA 3.23Å; L308-I312 WeakPolarHBondContact O-CB 3.33Å; L308-I312 WeakPolarHBondContact O-CG2 3.45Å; L308-I312 PolarHBondContact O-N 3.39Å; I312-W315 PolarHBondContact O-N 2.79Å; I312-M316 HydrophobicContact CG1-CG 4.27Å; I312-M316 HydrophobicContact CG1-SD 4.01Å; I312-M316 VanDerWaalsContact O-CB 3.27Å; I312-M316 WeakPolarHBondContact O-CB 3.49Å; I312-M316 WeakPolarHBondContact O-CG 3.2Å; I312-M316 PolarHBondContact O-N 3.01Å; I312-W331 HydrophobicContact CG2-CZ2 3.99Å; I312-L383 HydrophobicContact CD1-CD1 4.19Å; I312-L383 HydrophobicContact CD1-CD2 4.47Å; I312-L387 HydrophobicContact CD1-CD1 3.75Å; I312-L387 HydrophobicContact CD1-CD2 3.65Å; I312-L387 HydrophobicContact CD1-CG 4.13Å
313	A	76.9	Confident	78.4	Confident	9 Å²	9	32.4 Å²	32.4	7%	0.074	18%	0.184	C	C	.	.	H	α-helix	trans	-63	-49.9	177.6	0	0	0	0	0	110.7	T311 W315 M316 K317 M327	T311-A313 PolarHBondContact O-N 3.18Å; A313-W315 PolarHBondContact O-N 3.47Å; A313-M316 PolarHBondContact O-N 2.64Å; A313-K317 WeakPolarHBondContact O-CB 3.34Å; A313-K317 PolarHBondContact O-N 3.34Å; A313-M327 HydrophobicContact CB-SD 3.76Å
314	T	74	Confident	77.4	Confident	30 Å²	30	33.1 Å²	33.1	18%	0.184	19%	0.186	C	C	.	.	H	α-helix	trans	-60.5	-45.5	176.5	-55.2	0	0	0	0	111.3	T311 K317 H318	T311-T314 PolarHBondContact O-N 3.15Å; T314-K317 PolarHBondContact O-N 2.89Å; T314-H318 PolarHBondContact O-CD2 2.9Å; T314-H318 PolarHBondContact O-N 3.03Å; T314-H318 VanDerWaalsContact O-N 3.1Å
315	W	77.2	Confident	76.5	Confident	39 Å²	39	38 Å²	38	15%	0.148	20%	0.204	C	C	.	.	H	α-helix	trans	-64.1	-43.8	178.6	-179.8	83.3	0	0	0	112.5	T311 I312 A313 K317 H318 T319 M320 C377 L383 F448	T311-W315 VanDerWaalsContact O-CB 3.3Å; T311-W315 WeakPolarHBondContact O-CB 3.3Å; T311-W315 PolarHBondContact O-N 3.12Å; I312-W315 PolarHBondContact O-N 2.79Å; A313-W315 PolarHBondContact O-N 3.47Å; W315-K317 VanDerWaalsContact C-N 3.34Å; W315-K317 PolarHBondContact O-N 2.78Å; W315-H318 PolarHBondContact O-N 3.17Å; W315-T319 HydrophobicContact CZ2-CG2 4.16Å; W315-T319 PolarHBondContact NE1-OG1 3.05Å; W315-T319 VanDerWaalsContact O-CB 3.32Å; W315-T319 WeakPolarHBondContact O-CB 3.37Å; W315-T319 PolarHBondContact O-N 3.24Å; W315-T319 PolarHBondContact O-OG1 2.78Å; W315-M320 HydrophobicContact CH2-CE 3.74Å; W315-M320 HydrophobicContact CZ3-CE 3.82Å; W315-C377 VanDerWaalsContact CH2-O 3.23Å; W315-C377 WeakPolarHBondContact CH2-O 3.05Å; W315-L383 HydrophobicContact CH2-CD1 4.25Å; W315-L383 HydrophobicContact CZ3-CD1 3.7Å; W315-L383 HydrophobicContact CZ3-CD2 3.89Å; W315-L383 HydrophobicContact CZ3-CG 4.38Å; W315-F448 AromaticContact CD1-CD1 3.88Å; W315-F448 HydrophobicContact CD2-CE1 4.22Å; W315-F448 HydrophobicContact CG-CD1 4.4Å; W315-F448 HydrophobicContact CG-CE1 4.27Å; W315-F448 HydrophobicContact CG-CZ 4.39Å; W315-F448 AromaticContact NE1-CD1 3.81Å
316	M	75.8	Confident	76	Confident	1 Å²	1	40 Å²	40	1%	0.005	21%	0.213	C	C	.	.	H	α-helix	trans	-61.6	-40.4	175.8	-77.7	173.8	50.1	0	0	112.3	I312 A313 H318 M320 A321 A322 M327 A330 F380 L383	I312-M316 HydrophobicContact CG1-CG 4.27Å; I312-M316 HydrophobicContact CG1-SD 4.01Å; I312-M316 VanDerWaalsContact O-CB 3.27Å; I312-M316 WeakPolarHBondContact O-CB 3.49Å; I312-M316 WeakPolarHBondContact O-CG 3.2Å; I312-M316 PolarHBondContact O-N 3.01Å; A313-M316 PolarHBondContact O-N 2.64Å; M316-H318 PolarHBondContact O-N 2.95Å; M316-M320 CarbonylContact O-C 3.56Å; M316-M320 WeakPolarHBondContact O-CA 3.28Å; M316-M320 WeakPolarHBondContact O-CB 3.5Å; M316-M320 PolarHBondContact O-N 3.42Å; M316-A321 PolarHBondContact O-N 2.9Å; M316-A322 HydrophobicContact CB-CB 4.21Å; M316-A322 HydrophobicContact CE-CB 4.07Å; M316-A322 PolarHBondContact O-N 3.3Å; M316-M327 VanDerWaalsContact CE-CA 3.5Å; M316-M327 HydrophobicContact CE-CB 4.17Å; M316-M327 HydrophobicContact CE-CG 3.97Å; M316-A330 HydrophobicContact CE-CB 4.18Å; M316-A330 HydrophobicContact SD-CB 4.15Å; M316-F380 HydrophobicContact CE-CE2 4.33Å; M316-L383 HydrophobicContact CG-CD2 3.67Å; M316-L383 HydrophobicContact SD-CD2 3.64Å
317	K	74.1	Confident	75.4	Confident	107 Å²	107	40.9 Å²	40.9	47%	0.465	22%	0.217	S	C	.	.	H	α-helix	trans	-63.4	-40.8	176.9	-167.9	170	-175.7	167.5	0	111.8	A313 T314 W315 A321 M327	A313-K317 WeakPolarHBondContact O-CB 3.34Å; A313-K317 PolarHBondContact O-N 3.34Å; T314-K317 PolarHBondContact O-N 2.89Å; W315-K317 VanDerWaalsContact C-N 3.34Å; W315-K317 PolarHBondContact O-N 2.78Å; K317-A321 WeakPolarHBondContact O-CA 3.34Å; K317-A321 PolarHBondContact O-N 3.07Å; K317-M327 HydrophobicContact CB-SD 4.41Å
318	H	70.4	Confident	74.9	Confident	122 Å²	122	40.9 Å²	40.9	57%	0.565	22%	0.218	S	C	*	.	H	α-helix	trans	-80.9	-40.4	-178.7	-76.7	-65.1	0	0	0	114.3	T314 W315 M316	T314-H318 PolarHBondContact O-CD2 2.9Å; T314-H318 PolarHBondContact O-N 3.03Å; T314-H318 VanDerWaalsContact O-N 3.1Å; W315-H318 PolarHBondContact O-N 3.17Å; M316-H318 PolarHBondContact O-N 2.95Å
319	T	74.6	Confident	74.8	Confident	80 Å²	80	43.8 Å²	43.8	49%	0.491	23%	0.232	S	C	.	.	H	α-helix	trans	-89.2	-32.8	-173.9	-56.9	0	0	0	0	112.5	W315	W315-T319 HydrophobicContact CZ2-CG2 4.16Å; W315-T319 PolarHBondContact NE1-OG1 3.05Å; W315-T319 VanDerWaalsContact O-CB 3.32Å; W315-T319 WeakPolarHBondContact O-CB 3.37Å; W315-T319 PolarHBondContact O-N 3.24Å; W315-T319 PolarHBondContact O-OG1 2.78Å
320	M	75.6	Confident	74.9	Confident	45 Å²	45	43.7 Å²	43.7	22%	0.222	23%	0.232	C	C	.	.	H	α-helix	trans	-116.8	-2.4	-173.1	-56.4	-172.9	175.5	0	0	114	W315 M316 A322 C377 S379 L383	W315-M320 HydrophobicContact CH2-CE 3.74Å; W315-M320 HydrophobicContact CZ3-CE 3.82Å; M316-M320 CarbonylContact O-C 3.56Å; M316-M320 WeakPolarHBondContact O-CA 3.28Å; M316-M320 WeakPolarHBondContact O-CB 3.5Å; M316-M320 PolarHBondContact O-N 3.42Å; M320-A322 PolarHBondContact O-N 3Å; M320-C377 VanDerWaalsContact CE-O 3.29Å; M320-C377 WeakPolarHBondContact CE-O 3.44Å; M320-S379 WeakPolarHBondContact CE-O 3.22Å; M320-L383 HydrophobicContact CE-CB 4.47Å; M320-L383 HydrophobicContact CE-CD2 4.4Å; M320-L383 HydrophobicContact SD-CD2 4.41Å
321	A	70.3	Confident	75.3	Confident	89 Å²	89	43.7 Å²	43.7	74%	0.736	23%	0.23	S	C	*	.			trans	50.7	34.3	-173.2	0	0	0	0	0	112.9	M316 K317	M316-A321 PolarHBondContact O-N 2.9Å; K317-A321 WeakPolarHBondContact O-CA 3.34Å; K317-A321 PolarHBondContact O-N 3.07Å
322	A	70.7	Confident	75.7	Confident	13 Å²	13	47.5 Å²	47.5	11%	0.107	25%	0.249	C	C	.	.			trans	-68.3	143.7	-175.3	0	0	0	0	0	111.8	M316 M320 E326	M316-A322 HydrophobicContact CB-CB 4.21Å; M316-A322 HydrophobicContact CE-CB 4.07Å; M316-A322 PolarHBondContact O-N 3.3Å; M320-A322 PolarHBondContact O-N 3Å; A322-E326 HydrophobicContact CB-CB 4.35Å
323	S	73.8	Confident	76.1	Confident	41 Å²	41	49.9 Å²	49.9	29%	0.287	27%	0.265	S	S	.	.			trans	-76.8	161.9	173.7	57.6	0	0	0	0	112.1	W325 E326 M327	S323-W325 PolarHBondContact O-N 3.26Å; S323-W325 VanDerWaalsContact OG-CD1 3.27Å; S323-W325 PolarHBondContact OG-NE1 3.41Å; S323-E326 PolarHBondContact N-OE2 3.34Å; S323-E326 WeakPolarHBondContact O-CB 3.45Å; S323-E326 PolarHBondContact O-N 3.12Å; S323-E326 VanDerWaalsContact O-N 3.12Å; S323-E326 WeakPolarHBondContact OG-CG 3.33Å; S323-E326 PolarHBondContact OG-OE2 3.18Å; S323-M327 WeakPolarHBondContact O-CG 3.22Å; S323-M327 PolarHBondContact O-N 3.13Å; S323-M327 VanDerWaalsContact O-N 3.16Å
324	E	68.9	Low	76.5	Confident	60 Å²	60	49.5 Å²	49.5	28%	0.28	26%	0.262	S	S	.	.	H	α-helix	trans	-64.1	-37.4	-171.3	-62.2	-175.3	172.5	0	0	113.8	Y236 M327 G328	Y236-E324 WeakPolarHBondContact CE1-OE2 3.23Å; E324-M327 HydrophobicContact CB-CE 4.06Å; E324-M327 HydrophobicContact CG-CE 3.81Å; E324-M327 WeakPolarHBondContact O-CB 3.46Å; E324-M327 PolarHBondContact O-N 3.28Å; E324-G328 PolarHBondContact O-N 3.38Å
325	W	71.4	Confident	77	Confident	103 Å²	103	51.4 Å²	51.4	39%	0.39	27%	0.268	S	S	.	.	H	α-helix	trans	-69.1	-34.4	174.1	69.3	-81.5	0	0	0	112.4	E237 S323 M327 G328 M329	E237-W325 WeakPolarHBondContact OE2-CB 3.32Å; S323-W325 PolarHBondContact O-N 3.26Å; S323-W325 VanDerWaalsContact OG-CD1 3.27Å; S323-W325 PolarHBondContact OG-NE1 3.41Å; W325-M327 VanDerWaalsContact C-N 3.29Å; W325-M327 PolarHBondContact O-N 3.08Å; W325-G328 PolarHBondContact O-N 3.23Å; W325-M329 HydrophobicContact CD2-CE 4.29Å; W325-M329 HydrophobicContact CE3-CE 3.24Å; W325-M329 HydrophobicContact CE3-CG 4.09Å; W325-M329 HydrophobicContact CE3-SD 3.4Å; W325-M329 HydrophobicContact CH2-CE 3.64Å; W325-M329 HydrophobicContact CZ3-CE 2.9Å; W325-M329 HydrophobicContact CZ3-SD 3.34Å; W325-M329 WeakPolarHBondContact CZ3-SD 3.44Å; W325-M329 WeakPolarHBondContact O-CB 3.13Å; W325-M329 VanDerWaalsContact O-CG 3.3Å; W325-M329 WeakPolarHBondContact O-CG 3.33Å; W325-M329 PolarHBondContact O-N 3.04Å
326	E	76.5	Confident	77.5	Confident	64 Å²	64	54.5 Å²	54.5	30%	0.299	29%	0.29	S	S	.	.	H	α-helix	trans	-64	-35	174.8	-72	169.6	150.3	0	0	111.8	A322 S323 M329 A330 F380	A322-E326 HydrophobicContact CB-CB 4.35Å; S323-E326 PolarHBondContact N-OE2 3.34Å; S323-E326 WeakPolarHBondContact O-CB 3.45Å; S323-E326 PolarHBondContact O-N 3.12Å; S323-E326 VanDerWaalsContact O-N 3.12Å; S323-E326 WeakPolarHBondContact OG-CG 3.33Å; S323-E326 PolarHBondContact OG-OE2 3.18Å; E326-M329 HydrophobicContact CG-CE 4.45Å; E326-M329 PolarHBondContact O-N 3.19Å; E326-A330 PolarHBondContact O-N 3.27Å; E326-A330 VanDerWaalsContact O-N 3.12Å; E326-F380 HydrophobicContact CB-CE2 4.48Å
327	M	75.3	Confident	78.2	Confident	17 Å²	17	55.8 Å²	55.8	8%	0.084	30%	0.299	C	S	.	.	H	α-helix	trans	-62.2	-45.1	173.3	-57	-166.9	-77.4	0	0	112	A313 M316 K317 S323 E324 W325	A313-M327 HydrophobicContact CB-SD 3.76Å; M316-M327 VanDerWaalsContact CE-CA 3.5Å; M316-M327 HydrophobicContact CE-CB 4.17Å; M316-M327 HydrophobicContact CE-CG 3.97Å; K317-M327 HydrophobicContact CB-SD 4.41Å; S323-M327 WeakPolarHBondContact O-CG 3.22Å; S323-M327 PolarHBondContact O-N 3.13Å; S323-M327 VanDerWaalsContact O-N 3.16Å; E324-M327 HydrophobicContact CB-CE 4.06Å; E324-M327 HydrophobicContact CG-CE 3.81Å; E324-M327 WeakPolarHBondContact O-CB 3.46Å; E324-M327 PolarHBondContact O-N 3.28Å; W325-M327 VanDerWaalsContact C-N 3.29Å; W325-M327 PolarHBondContact O-N 3.08Å
328	G	73.9	Confident	78.9	Confident	2 Å²	2	51.7 Å²	51.7	2%	0.021	28%	0.281	C	S	.	.	H	α-helix	trans	-68.4	-40.2	176.7	0	0	0	0	0	112.9	E324 W325 A330	E324-G328 PolarHBondContact O-N 3.38Å; W325-G328 PolarHBondContact O-N 3.23Å; G328-A330 VanDerWaalsContact C-N 3.31Å; G328-A330 PolarHBondContact O-N 2.53Å
329	M	80.3	Confident	79.7	Confident	62 Å²	62	49.1 Å²	49.1	31%	0.305	27%	0.274	S	S	.	.	H	α-helix	trans	-70.6	-21.1	-179.4	-75.1	-159.4	-41.2	0	0	114.4	W325 E326 W331 L332 P333	W325-M329 HydrophobicContact CD2-CE 4.29Å; W325-M329 HydrophobicContact CE3-CE 3.24Å; W325-M329 HydrophobicContact CE3-CG 4.09Å; W325-M329 HydrophobicContact CE3-SD 3.4Å; W325-M329 HydrophobicContact CH2-CE 3.64Å; W325-M329 HydrophobicContact CZ3-CE 2.9Å; W325-M329 HydrophobicContact CZ3-SD 3.34Å; W325-M329 WeakPolarHBondContact CZ3-SD 3.44Å; W325-M329 WeakPolarHBondContact O-CB 3.13Å; W325-M329 VanDerWaalsContact O-CG 3.3Å; W325-M329 WeakPolarHBondContact O-CG 3.33Å; W325-M329 PolarHBondContact O-N 3.04Å; E326-M329 HydrophobicContact CG-CE 4.45Å; E326-M329 PolarHBondContact O-N 3.19Å; M329-W331 PolarHBondContact O-N 3.3Å; M329-W331 VanDerWaalsContact O-N 3.12Å; M329-L332 WeakPolarHBondContact O-CB 2.81Å; M329-L332 PolarHBondContact O-N 3.01Å; M329-P333 WeakPolarHBondContact O-CD 3.44Å
330	A	82.1	Confident	80.5	Confident	0 Å²	0	49.9 Å²	49.9	0%	0	28%	0.275	C	S	.	.	T	Hydrogen-bonded Turn	trans	-56.6	-29.6	179.7	0	0	0	0	0	112.9	M316 E326 G328 F380 L387	M316-A330 HydrophobicContact CE-CB 4.18Å; M316-A330 HydrophobicContact SD-CB 4.15Å; E326-A330 PolarHBondContact O-N 3.27Å; E326-A330 VanDerWaalsContact O-N 3.12Å; G328-A330 VanDerWaalsContact C-N 3.31Å; G328-A330 PolarHBondContact O-N 2.53Å; A330-F380 HydrophobicContact CB-CE2 4.12Å; A330-F380 HydrophobicContact CB-CZ 4.48Å; A330-L387 HydrophobicContact CB-CD1 4.26Å
331	W	82.9	Confident	81.1	Confident	13 Å²	13	47.7 Å²	47.7	5%	0.049	26%	0.264	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82.8	-21.6	178.8	-67.2	98.6	0	0	0	114	L226 P229 L305 E309 I312 M329 A334 L387	L226-W331 HydrophobicContact CD1-CB 4.44Å; P229-W331 HydrophobicContact CB-CG 4.49Å; P229-W331 HydrophobicContact CG-CB 4.39Å; P229-W331 HydrophobicContact CG-CG 4.32Å; L305-W331 HydrophobicContact CD1-CH2 3.54Å; L305-W331 HydrophobicContact CD1-CZ3 3.5Å; L305-W331 VanDerWaalsContact CD1-CZ3 3.5Å; E309-W331 HydrophobicContact CG-CH2 4.44Å; E309-W331 HydrophobicContact CG-CZ2 4.29Å; I312-W331 HydrophobicContact CG2-CZ2 3.99Å; M329-W331 PolarHBondContact O-N 3.3Å; M329-W331 VanDerWaalsContact O-N 3.12Å; W331-A334 WeakPolarHBondContact O-CB 3.09Å; W331-A334 PolarHBondContact O-N 3.44Å; W331-L387 HydrophobicContact CH2-CD2 4Å; W331-L387 HydrophobicContact CZ2-CD2 4.44Å; W331-L387 HydrophobicContact CZ3-CD2 4.16Å
332	L	85.1	Confident	82	Confident	98 Å²	98	45.6 Å²	45.6	51%	0.513	24%	0.242	S	C	.	.	S	Bend	trans	-66.6	-44.6	-172.9	-171.4	148.4	0	0	0	112.7	P230 M329 A334 F335	P230-L332 HydrophobicContact CB-CD1 3.99Å; P230-L332 HydrophobicContact CG-CB 3.95Å; P230-L332 HydrophobicContact CG-CD1 3.86Å; P230-L332 HydrophobicContact CG-CG 4.38Å; M329-L332 WeakPolarHBondContact O-CB 2.81Å; M329-L332 PolarHBondContact O-N 3.01Å; L332-A334 PolarHBondContact O-N 2.92Å; L332-F335 WeakPolarHBondContact O-CB 3.36Å; L332-F335 PolarHBondContact O-N 3.12Å; L332-F335 VanDerWaalsContact O-N 3.14Å
333	P	87.8	Confident	82.8	Confident	53 Å²	53	50.7 Å²	50.7	34%	0.344	26%	0.259	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.4	-26.5	174.1	-24.2	34.5	0	0	0	113.7	M329 F335 V336 P337 V384	M329-P333 WeakPolarHBondContact O-CD 3.44Å; P333-F335 PolarHBondContact O-N 3.38Å; P333-F335 VanDerWaalsContact O-N 3.14Å; P333-V336 PolarHBondContact O-N 3.4Å; P333-P337 WeakPolarHBondContact O-CD 3.28Å; P333-V384 HydrophobicContact CB-CG1 3.5Å; P333-V384 VanDerWaalsContact CB-CG1 3.5Å; P333-V384 HydrophobicContact CG-CG1 3.7Å
334	A	85.7	Confident	83.6	Confident	0 Å²	0	52 Å²	52	0%	0	26%	0.263	C	S	.	.	T	Hydrogen-bonded Turn	trans	-67	-11.3	177.9	0	0	0	0	0	113.1	W331 L332 P337 H338 L387 C391	W331-A334 WeakPolarHBondContact O-CB 3.09Å; W331-A334 PolarHBondContact O-N 3.44Å; L332-A334 PolarHBondContact O-N 2.92Å; A334-P337 WeakPolarHBondContact O-CD 3.2Å; A334-H338 WeakPolarHBondContact O-CB 3.44Å; A334-H338 PolarHBondContact O-N 2.85Å; A334-L387 HydrophobicContact CB-CB 4.49Å; A334-C391 HydrophobicContact CB-CB 4.1Å
335	F	84	Confident	84.5	Confident	71 Å²	71	49.2 Å²	49.2	31%	0.311	25%	0.25	S	C	.	.	H	α-helix	trans	-64	-46.6	175.6	-174	-128.5	0	0	0	113.5	F223 L226 L332 P333 H338 V339	F223-F335 HydrophobicContact CD2-CE2 4.01Å; F223-F335 AromaticContact CD2-CZ 3.88Å; F223-F335 HydrophobicContact CD2-CZ 3.88Å; F223-F335 HydrophobicContact CE2-CZ 4.26Å; L226-F335 HydrophobicContact CB-CD2 4.48Å; L226-F335 HydrophobicContact CD2-CB 3.14Å; L226-F335 HydrophobicContact CD2-CD2 3.27Å; L226-F335 HydrophobicContact CD2-CE2 4.43Å; L226-F335 HydrophobicContact CD2-CG 3.59Å; L226-F335 HydrophobicContact CG-CB 4.34Å; L226-F335 HydrophobicContact CG-CD2 4.46Å; L332-F335 WeakPolarHBondContact O-CB 3.36Å; L332-F335 PolarHBondContact O-N 3.12Å; L332-F335 VanDerWaalsContact O-N 3.14Å; P333-F335 PolarHBondContact O-N 3.38Å; P333-F335 VanDerWaalsContact O-N 3.14Å; F335-H338 PolarHBondContact O-N 2.94Å; F335-H338 VanDerWaalsContact O-N 3.15Å; F335-V339 HydrophobicContact CD1-CG2 4.48Å; F335-V339 HydrophobicContact CD2-CG2 3.65Å; F335-V339 HydrophobicContact CE1-CG2 4.14Å; F335-V339 HydrophobicContact CE2-CG2 3.31Å; F335-V339 HydrophobicContact CG-CG2 4.28Å; F335-V339 HydrophobicContact CZ-CG2 3.59Å; F335-V339 WeakPolarHBondContact O-CG2 3.47Å; F335-V339 PolarHBondContact O-N 2.86Å
336	V	88.6	Confident	85.2	Confident	103 Å²	103	48.3 Å²	48.3	62%	0.624	26%	0.255	S	S	*	.	H	α-helix	trans	-63	-47.5	-174.4	178.1	0	0	0	0	109.7	P333 L340	P333-V336 PolarHBondContact O-N 3.4Å; V336-L340 WeakPolarHBondContact O-CB 3.49Å; V336-L340 PolarHBondContact O-N 3.19Å
337	P	90.9	Very high	85.6	Confident	29 Å²	29	53.1 Å²	53.1	19%	0.188	27%	0.271	C	S	.	.	H	α-helix	trans	-61.3	-42.6	170.4	-24.2	35.3	0	0	0	113.5	P333 A334 V339 L340 G341 C388 F392	P333-P337 WeakPolarHBondContact O-CD 3.28Å; A334-P337 WeakPolarHBondContact O-CD 3.2Å; P337-V339 PolarHBondContact O-N 3.2Å; P337-L340 PolarHBondContact O-N 2.96Å; P337-G341 PolarHBondContact O-N 2.9Å; P337-C388 HydrophobicContact CB-CB 4.31Å; P337-C388 HydrophobicContact CG-CB 3.66Å; P337-F392 HydrophobicContact CB-CB 3.97Å; P337-F392 WeakPolarHBondContact O-CD2 3.47Å
338	H	89.1	Confident	86.1	Confident	20 Å²	20	54.8 Å²	54.8	9%	0.093	28%	0.28	C	S	.	.	H	α-helix	trans	-58.7	-51.5	179.6	-173	78.6	0	0	0	112	S222 A334 F335 L340 G341 V342 C391 A395	S222-H338 VanDerWaalsContact CB-NE2 3.3Å; S222-H338 WeakPolarHBondContact CB-NE2 3.34Å; S222-H338 PolarHBondContact OG-NE2 3.27Å; A334-H338 WeakPolarHBondContact O-CB 3.44Å; A334-H338 PolarHBondContact O-N 2.85Å; F335-H338 PolarHBondContact O-N 2.94Å; F335-H338 VanDerWaalsContact O-N 3.15Å; H338-L340 VanDerWaalsContact C-N 3.33Å; H338-L340 PolarHBondContact O-N 3.36Å; H338-G341 WeakPolarHBondContact O-CA 3.35Å; H338-G341 PolarHBondContact O-N 3.4Å; H338-G341 VanDerWaalsContact O-N 3.12Å; H338-V342 PolarHBondContact O-N 3.48Å; H338-C391 HydrophobicContact CB-CB 4.13Å; H338-C391 PolarHBondContact ND1-O 3.22Å; H338-A395 VanDerWaalsContact O-CB 3.28Å; H338-A395 WeakPolarHBondContact O-CB 3.35Å
339	V	87.1	Confident	86.5	Confident	69 Å²	69	55.6 Å²	55.6	42%	0.418	29%	0.286	S	S	.	.	H	α-helix	trans	-62.6	-40.5	177.3	175.1	0	0	0	0	111.4	F335 P337 G341 V342 Y343	F335-V339 HydrophobicContact CD1-CG2 4.48Å; F335-V339 HydrophobicContact CD2-CG2 3.65Å; F335-V339 HydrophobicContact CE1-CG2 4.14Å; F335-V339 HydrophobicContact CE2-CG2 3.31Å; F335-V339 HydrophobicContact CG-CG2 4.28Å; F335-V339 HydrophobicContact CZ-CG2 3.59Å; F335-V339 WeakPolarHBondContact O-CG2 3.47Å; F335-V339 PolarHBondContact O-N 2.86Å; P337-V339 PolarHBondContact O-N 3.2Å; V339-G341 VanDerWaalsContact C-N 3.29Å; V339-G341 PolarHBondContact O-N 3.29Å; V339-V342 PolarHBondContact O-N 3.43Å; V339-Y343 WeakPolarHBondContact O-CB 3.24Å; V339-Y343 PolarHBondContact O-N 2.98Å
340	L	89.7	Confident	86.5	Confident	95 Å²	95	56.8 Å²	56.8	50%	0.497	31%	0.306	S	S	.	.	H	α-helix	trans	-61.4	-39.8	174.9	-178.9	63.7	0	0	0	111.5	V336 P337 H338 Y343 L344	V336-L340 WeakPolarHBondContact O-CB 3.49Å; V336-L340 PolarHBondContact O-N 3.19Å; P337-L340 PolarHBondContact O-N 2.96Å; H338-L340 VanDerWaalsContact C-N 3.33Å; H338-L340 PolarHBondContact O-N 3.36Å; L340-Y343 PolarHBondContact O-N 3.34Å; L340-L344 WeakPolarHBondContact O-CB 3.26Å; L340-L344 PolarHBondContact O-N 2.99Å
341	G	89.5	Confident	86.7	Confident	0 Å²	0	65.7 Å²	65.7	0%	0	34%	0.34	C	S	.	.	H	α-helix	trans	-61.7	-48.2	175.4	0	0	0	0	0	112	P337 H338 V339 L344 T345 F392	P337-G341 PolarHBondContact O-N 2.9Å; H338-G341 WeakPolarHBondContact O-CA 3.35Å; H338-G341 PolarHBondContact O-N 3.4Å; H338-G341 VanDerWaalsContact O-N 3.12Å; V339-G341 VanDerWaalsContact C-N 3.29Å; V339-G341 PolarHBondContact O-N 3.29Å; G341-L344 PolarHBondContact O-N 3.12Å; G341-T345 WeakPolarHBondContact O-CB 3.49Å; G341-T345 PolarHBondContact O-N 3.26Å; G341-T345 PolarHBondContact O-OG1 3.21Å; G341-F392 VanDerWaalsContact CA-CE2 3.49Å
342	V	88	Confident	86.7	Confident	44 Å²	44	69.7 Å²	69.7	27%	0.267	36%	0.355	S	S	.	.	H	α-helix	trans	-59	-51.6	174.6	178.5	0	0	0	0	110.3	H338 V339 L344 T345 V346 A395 T399	H338-V342 PolarHBondContact O-N 3.48Å; V339-V342 PolarHBondContact O-N 3.43Å; V342-L344 PolarHBondContact O-N 3.37Å; V342-T345 PolarHBondContact O-N 3.36Å; V342-V346 HydrophobicContact CG1-CG2 4.35Å; V342-V346 WeakPolarHBondContact O-CG2 3.39Å; V342-V346 PolarHBondContact O-N 3Å; V342-A395 HydrophobicContact CG2-CB 3.87Å; V342-T399 HydrophobicContact CG1-CG2 4.24Å
343	Y	87.9	Confident	86.2	Confident	120 Å²	120	68.8 Å²	68.8	47%	0.471	36%	0.355	S	S	.	.	H	α-helix	trans	-58.5	-46.9	-179.1	176.3	-101.1	0	0	0	112.8	V339 L340 R347	V339-Y343 WeakPolarHBondContact O-CB 3.24Å; V339-Y343 PolarHBondContact O-N 2.98Å; L340-Y343 PolarHBondContact O-N 3.34Å; Y343-R347 PolarHBondContact O-N 2.95Å; Y343-R347 PolarHBondContact OH-NE 3.22Å; Y343-R347 PolarHBondContact OH-NH1 2.92Å; Y343-R347 PolarHBondContact OH-NH2 3.41Å; Y343-R347 VanDerWaalsContact OH-NH2 3.15Å
344	L	90.4	Very high	85.7	Confident	70 Å²	70	71.4 Å²	71.4	37%	0.366	36%	0.363	S	S	.	.	H	α-helix	trans	-61.7	-46.3	178.8	-179.6	64.1	0	0	0	110.5	L340 G341 V342 R347 L348 F392	L340-L344 WeakPolarHBondContact O-CB 3.26Å; L340-L344 PolarHBondContact O-N 2.99Å; G341-L344 PolarHBondContact O-N 3.12Å; V342-L344 PolarHBondContact O-N 3.37Å; L344-R347 PolarHBondContact O-N 3.38Å; L344-L348 HydrophobicContact CD1-CD1 3.91Å; L344-L348 HydrophobicContact CD1-CG 4.19Å; L344-L348 HydrophobicContact CD2-CD1 4.45Å; L344-L348 HydrophobicContact CG-CD1 3.75Å; L344-L348 HydrophobicContact CG-CG 4.4Å; L344-L348 VanDerWaalsContact O-CB 3.32Å; L344-L348 WeakPolarHBondContact O-CB 3.47Å; L344-L348 VanDerWaalsContact O-CG 3.23Å; L344-L348 WeakPolarHBondContact O-CG 3.36Å; L344-L348 PolarHBondContact O-N 3.48Å; L344-F392 HydrophobicContact CD2-CE2 4.3Å; L344-F392 HydrophobicContact CD2-CZ 3.96Å
345	T	88.1	Confident	85.7	Confident	0 Å²	0	73.6 Å²	73.6	0%	0	37%	0.374	C	S	.	.	H	α-helix	trans	-64.8	-43.7	-179	-50.1	0	0	0	0	111.7	G341 V342 R347 L348 A349 L396 T399 A400	G341-T345 WeakPolarHBondContact O-CB 3.49Å; G341-T345 PolarHBondContact O-N 3.26Å; G341-T345 PolarHBondContact O-OG1 3.21Å; V342-T345 PolarHBondContact O-N 3.36Å; T345-R347 PolarHBondContact O-N 3.23Å; T345-L348 PolarHBondContact O-N 3.11Å; T345-A349 WeakPolarHBondContact O-CB 3.34Å; T345-A349 PolarHBondContact O-N 3.38Å; T345-L396 WeakPolarHBondContact OG1-CD2 2.93Å; T345-T399 HydrophobicContact CG2-CG2 3.82Å; T345-A400 HydrophobicContact CG2-CB 3.95Å
346	V	86	Confident	85.6	Confident	84 Å²	84	72.1 Å²	72.1	51%	0.509	37%	0.368	S	S	.	.	H	α-helix	trans	-60.8	-46.1	176	172.2	0	0	0	0	111.1	V342 L348 A349 A350 T399	V342-V346 HydrophobicContact CG1-CG2 4.35Å; V342-V346 WeakPolarHBondContact O-CG2 3.39Å; V342-V346 PolarHBondContact O-N 3Å; V346-L348 PolarHBondContact O-N 3.34Å; V346-A349 PolarHBondContact O-N 3.11Å; V346-A350 WeakPolarHBondContact O-CB 3.15Å; V346-A350 PolarHBondContact O-N 3.35Å; V346-T399 HydrophobicContact CG2-CG2 3.62Å
347	R	86.4	Confident	85.5	Confident	166 Å²	166	69.2 Å²	69.2	63%	0.626	35%	0.346	S	S	*	.	H	α-helix	trans	-62.9	-42.7	177.6	-102.7	-169.2	168.8	175.3	1.4	112.5	Y343 L344 T345 R351	Y343-R347 PolarHBondContact O-N 2.95Å; Y343-R347 PolarHBondContact OH-NE 3.22Å; Y343-R347 PolarHBondContact OH-NH1 2.92Å; Y343-R347 PolarHBondContact OH-NH2 3.41Å; Y343-R347 VanDerWaalsContact OH-NH2 3.15Å; L344-R347 PolarHBondContact O-N 3.38Å; T345-R347 PolarHBondContact O-N 3.23Å; R347-R351 PolarHBondContact O-N 3.39Å
348	L	85.9	Confident	85.4	Confident	51 Å²	51	71.4 Å²	71.4	27%	0.267	36%	0.356	S	S	.	.	H	α-helix	trans	-68.1	-43.6	178.8	-75	173.2	0	0	0	111.3	L344 T345 V346 A350 R351 Y352 Y359	L344-L348 HydrophobicContact CD1-CD1 3.91Å; L344-L348 HydrophobicContact CD1-CG 4.19Å; L344-L348 HydrophobicContact CD2-CD1 4.45Å; L344-L348 HydrophobicContact CG-CD1 3.75Å; L344-L348 HydrophobicContact CG-CG 4.4Å; L344-L348 VanDerWaalsContact O-CB 3.32Å; L344-L348 WeakPolarHBondContact O-CB 3.47Å; L344-L348 VanDerWaalsContact O-CG 3.23Å; L344-L348 WeakPolarHBondContact O-CG 3.36Å; L344-L348 PolarHBondContact O-N 3.48Å; T345-L348 PolarHBondContact O-N 3.11Å; V346-L348 PolarHBondContact O-N 3.34Å; L348-A350 VanDerWaalsContact C-N 3.31Å; L348-A350 PolarHBondContact O-N 3Å; L348-R351 PolarHBondContact O-N 2.95Å; L348-R351 VanDerWaalsContact O-N 3.12Å; L348-Y352 PolarHBondContact O-N 3.42Å; L348-Y359 HydrophobicContact CB-CE1 4.18Å; L348-Y359 HydrophobicContact CB-CE2 3.89Å; L348-Y359 HydrophobicContact CD1-CD1 4.36Å; L348-Y359 HydrophobicContact CD1-CE1 3.99Å
349	A	80.8	Confident	85.5	Confident	20 Å²	20	71.3 Å²	71.3	17%	0.165	36%	0.355	C	S	.	.	H	α-helix	trans	-62.6	-36.4	176.9	0	0	0	0	0	112.3	T345 V346 R351 P353	T345-A349 WeakPolarHBondContact O-CB 3.34Å; T345-A349 PolarHBondContact O-N 3.38Å; V346-A349 PolarHBondContact O-N 3.11Å; A349-R351 VanDerWaalsContact C-N 3.33Å; A349-P353 WeakPolarHBondContact O-CA 3.29Å
350	A	81.8	Confident	85.5	Confident	87 Å²	87	68 Å²	68	72%	0.719	34%	0.335	S	S	*	.	H	α-helix	trans	-66.5	-34.3	174.4	0	0	0	0	0	112.7	V346 L348	V346-A350 WeakPolarHBondContact O-CB 3.15Å; V346-A350 PolarHBondContact O-N 3.35Å; L348-A350 VanDerWaalsContact C-N 3.31Å; L348-A350 PolarHBondContact O-N 3Å
351	R	84.9	Confident	85.6	Confident	186 Å²	186	64.3 Å²	64.3	70%	0.702	32%	0.318	S	S	*	.	H	α-helix	trans	-86.2	-34.8	-178.9	-165.9	171.5	-178.8	155.5	2.5	113.1	R347 L348 A349	R347-R351 PolarHBondContact O-N 3.39Å; L348-R351 PolarHBondContact O-N 2.95Å; L348-R351 VanDerWaalsContact O-N 3.12Å; A349-R351 VanDerWaalsContact C-N 3.33Å
352	Y	83.3	Confident	85.8	Confident	97 Å²	97	69 Å²	69	38%	0.38	34%	0.342	S	S	.	.			trans	-137.6	73.8	-175.6	-57.4	-71.1	0	0	0	111.2	L348 H354 L355	L348-Y352 PolarHBondContact O-N 3.42Å; Y352-H354 VanDerWaalsContact C-N 3.26Å; Y352-H354 PolarHBondContact O-N 3.43Å; Y352-L355 HydrophobicContact CG-CD1 4.22Å; Y352-L355 PolarHBondContact O-N 3.32Å
353	P	74.6	Confident	86	Confident	79 Å²	79	66.9 Å²	66.9	51%	0.513	33%	0.329	S	S	.	.	G	3₁₀ helix	trans	-64.4	-27.7	-175.7	22.9	-33.1	0	0	0	113.6	A349 L355 Q356	A349-P353 WeakPolarHBondContact O-CA 3.29Å; P353-L355 PolarHBondContact O-N 3.4Å; P353-Q356 WeakPolarHBondContact O-CG 3.4Å
354	H	78.2	Confident	86.2	Confident	109 Å²	109	61.1 Å²	61.1	51%	0.505	31%	0.307	S	S	.	.	G	3₁₀ helix	trans	-72.7	-10.9	179.1	63.2	-83.6	0	0	0	114.2	Y352 W357	Y352-H354 VanDerWaalsContact C-N 3.26Å; Y352-H354 PolarHBondContact O-N 3.43Å; H354-W357 PolarHBondContact O-NE1 3.5Å
355	L	83.9	Confident	86.4	Confident	45 Å²	45	59.7 Å²	59.7	24%	0.236	31%	0.305	C	S	.	.	G	3₁₀ helix	trans	-99.2	9.9	-178.7	-64.3	177.8	0	0	0	113.5	Y352 P353 W357 L358 Y359	Y352-L355 HydrophobicContact CG-CD1 4.22Å; Y352-L355 PolarHBondContact O-N 3.32Å; P353-L355 PolarHBondContact O-N 3.4Å; L355-W357 VanDerWaalsContact C-N 3.25Å; L355-W357 PolarHBondContact O-N 3.44Å; L355-L358 HydrophobicContact CB-CB 4.49Å; L355-L358 HydrophobicContact CD2-CD2 4.39Å; L355-L358 WeakPolarHBondContact O-CA 3.25Å; L355-L358 VanDerWaalsContact O-CB 3.31Å; L355-L358 WeakPolarHBondContact O-CB 3.4Å; L355-L358 PolarHBondContact O-N 3.47Å; L355-Y359 HydrophobicContact CB-CE1 4.38Å; L355-Y359 HydrophobicContact CB-CE2 4.02Å; L355-Y359 WeakPolarHBondContact O-CD2 3.06Å; L355-Y359 PolarHBondContact O-N 3.2Å
356	Q	82.9	Confident	86.7	Confident	41 Å²	41	61.4 Å²	61.4	19%	0.192	32%	0.316	C	S	.	.	H	α-helix	trans	-53.4	-40.1	-179.9	-76.9	176	-13.7	0	0	113.4	P353 L358 Y359 G360 T404	P353-Q356 WeakPolarHBondContact O-CG 3.4Å; Q356-L358 VanDerWaalsContact C-N 3.27Å; Q356-L358 PolarHBondContact O-N 2.85Å; Q356-Y359 PolarHBondContact O-N 3.49Å; Q356-G360 PolarHBondContact O-N 2.92Å; Q356-G360 VanDerWaalsContact O-N 3.12Å; Q356-T404 PolarHBondContact OE1-OG1 2.86Å
357	W	86.1	Confident	87.1	Confident	42 Å²	42	57.4 Å²	57.4	16%	0.159	29%	0.291	C	S	.	.	H	α-helix	trans	-62	-33.4	176.3	68.8	-91.1	0	0	0	112.9	H354 L355 A361 L467 L469 R470	H354-W357 PolarHBondContact O-NE1 3.5Å; L355-W357 VanDerWaalsContact C-N 3.25Å; L355-W357 PolarHBondContact O-N 3.44Å; W357-A361 WeakPolarHBondContact O-CB 3.28Å; W357-A361 PolarHBondContact O-N 3.33Å; W357-L467 HydrophobicContact CE3-CD2 4.03Å; W357-L467 HydrophobicContact CH2-CD2 3.62Å; W357-L467 HydrophobicContact CZ3-CD2 3.27Å; W357-L467 HydrophobicContact CZ3-CG 4.3Å; W357-L469 HydrophobicContact CB-CB 3.95Å; W357-R470 HydrophobicContact CD2-CB 4.44Å; W357-R470 HydrophobicContact CZ2-CB 4.49Å; W357-R470 HydrophobicContact CZ2-CG 4.07Å
358	L	89.2	Confident	87.3	Confident	75 Å²	75	49.5 Å²	49.5	39%	0.393	26%	0.262	S	S	.	.	H	α-helix	trans	-71.6	-39	179.3	-179.2	67.6	0	0	0	110.7	L355 Q356 A361 L362	L355-L358 HydrophobicContact CB-CB 4.49Å; L355-L358 HydrophobicContact CD2-CD2 4.39Å; L355-L358 WeakPolarHBondContact O-CA 3.25Å; L355-L358 VanDerWaalsContact O-CB 3.31Å; L355-L358 WeakPolarHBondContact O-CB 3.4Å; L355-L358 PolarHBondContact O-N 3.47Å; Q356-L358 VanDerWaalsContact C-N 3.27Å; Q356-L358 PolarHBondContact O-N 2.85Å; L358-A361 PolarHBondContact O-N 2.83Å; L358-L362 WeakPolarHBondContact O-CB 3.5Å; L358-L362 PolarHBondContact O-N 3.11Å
359	Y	90	Very high	87.6	Confident	18 Å²	18	49.5 Å²	49.5	7%	0.071	27%	0.269	C	S	.	.	H	α-helix	trans	-64.8	-41.3	175.4	-52.9	-40.6	0	0	0	111.3	L348 L355 Q356 L362 G363	L348-Y359 HydrophobicContact CB-CE1 4.18Å; L348-Y359 HydrophobicContact CB-CE2 3.89Å; L348-Y359 HydrophobicContact CD1-CD1 4.36Å; L348-Y359 HydrophobicContact CD1-CE1 3.99Å; L355-Y359 HydrophobicContact CB-CE1 4.38Å; L355-Y359 HydrophobicContact CB-CE2 4.02Å; L355-Y359 WeakPolarHBondContact O-CD2 3.06Å; L355-Y359 PolarHBondContact O-N 3.2Å; Q356-Y359 PolarHBondContact O-N 3.49Å; Y359-L362 PolarHBondContact O-N 3.02Å; Y359-G363 PolarHBondContact O-N 3.46Å
360	G	88.6	Confident	88.2	Confident	0 Å²	0	49 Å²	49	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-61.3	-44.1	171.6	0	0	0	0	0	112.8	Q356 G363 L364	Q356-G360 PolarHBondContact O-N 2.92Å; Q356-G360 VanDerWaalsContact O-N 3.12Å; G360-G363 PolarHBondContact O-N 2.75Å; G360-L364 PolarHBondContact O-N 2.82Å
361	A	91.1	Very high	88.5	Confident	16 Å²	16	45 Å²	45	13%	0.132	23%	0.23	C	C	.	.	H	α-helix	trans	-66.6	-40.2	178.9	0	0	0	0	0	112.4	W357 L358 L364 A365 L466	W357-A361 WeakPolarHBondContact O-CB 3.28Å; W357-A361 PolarHBondContact O-N 3.33Å; L358-A361 PolarHBondContact O-N 2.83Å; A361-L364 PolarHBondContact O-N 3.19Å; A361-A365 PolarHBondContact O-N 3.27Å; A361-L466 HydrophobicContact CB-CB 4.38Å; A361-L466 HydrophobicContact CB-CD1 4.01Å; A361-L466 VanDerWaalsContact N-CD1 3.28Å
362	L	93.3	Very high	88.6	Confident	98 Å²	98	38.3 Å²	38.3	51%	0.513	21%	0.212	S	C	.	.	H	α-helix	trans	-62.8	-44	172.9	-178	64.9	0	0	0	110.8	L358 Y359 A365 V366	L358-L362 WeakPolarHBondContact O-CB 3.5Å; L358-L362 PolarHBondContact O-N 3.11Å; Y359-L362 PolarHBondContact O-N 3.02Å; L362-A365 PolarHBondContact O-N 3.4Å; L362-V366 VanDerWaalsContact O-CG2 3.32Å; L362-V366 WeakPolarHBondContact O-CG2 3.41Å; L362-V366 PolarHBondContact O-N 2.87Å
363	G	92.3	Very high	88.8	Confident	0 Å²	0	38 Å²	38	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-56.6	-50.8	175	0	0	0	0	0	112	Y359 G360 A365 V366 I367	Y359-G363 PolarHBondContact O-N 3.46Å; G360-G363 PolarHBondContact O-N 2.75Å; G363-A365 VanDerWaalsContact C-N 3.32Å; G363-A365 PolarHBondContact O-N 3.47Å; G363-V366 PolarHBondContact O-N 3.18Å; G363-V366 VanDerWaalsContact O-N 3.17Å; G363-I367 VanDerWaalsContact O-CG1 3.25Å; G363-I367 WeakPolarHBondContact O-CG1 3.5Å; G363-I367 PolarHBondContact O-N 2.9Å
364	L	93.1	Very high	89.4	Confident	0 Å²	0	34.2 Å²	34.2	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-58.3	-40.6	175.8	-74.3	174.9	0	0	0	112.8	C301 G360 A361 I367 G368 V397 N459 Y462 A463 L466	C301-L364 HydrophobicContact CB-CD2 3.72Å; G360-L364 PolarHBondContact O-N 2.82Å; A361-L364 PolarHBondContact O-N 3.19Å; L364-I367 PolarHBondContact O-N 3.14Å; L364-G368 PolarHBondContact O-N 2.82Å; L364-V397 HydrophobicContact CD2-CG2 4.38Å; L364-V397 HydrophobicContact CG-CG2 4.12Å; L364-N459 WeakPolarHBondContact CD2-OD1 3.47Å; L364-Y462 HydrophobicContact CD1-CD1 4.13Å; L364-A463 HydrophobicContact CB-CB 4.12Å; L364-A463 HydrophobicContact CD1-CB 4.48Å; L364-L466 HydrophobicContact CD1-CD1 3.49Å; L364-L466 VanDerWaalsContact CD1-CD1 3.49Å; L364-L466 HydrophobicContact CD1-CG 4.25Å; L364-L466 HydrophobicContact CG-CD1 4.4Å
365	A	93.9	Very high	89.5	Confident	39 Å²	39	30 Å²	30	32%	0.322	17%	0.174	S	C	.	.	H	α-helix	trans	-64.6	-42.1	176.7	0	0	0	0	0	112.1	A361 L362 G363 G368 A369	A361-A365 PolarHBondContact O-N 3.27Å; L362-A365 PolarHBondContact O-N 3.4Å; G363-A365 VanDerWaalsContact C-N 3.32Å; G363-A365 PolarHBondContact O-N 3.47Å; A365-G368 PolarHBondContact O-N 3.38Å; A365-A369 WeakPolarHBondContact O-CB 3.34Å; A365-A369 PolarHBondContact O-N 3.07Å
366	V	94.6	Very high	89.5	Confident	37 Å²	37	31.5 Å²	31.5	22%	0.224	19%	0.193	C	C	.	.	H	α-helix	trans	-65	-42.9	176.2	173.6	0	0	0	0	111.1	L362 G363 A369 S370 G389 F392	L362-V366 VanDerWaalsContact O-CG2 3.32Å; L362-V366 WeakPolarHBondContact O-CG2 3.41Å; L362-V366 PolarHBondContact O-N 2.87Å; G363-V366 PolarHBondContact O-N 3.18Å; G363-V366 VanDerWaalsContact O-N 3.17Å; V366-A369 PolarHBondContact O-N 3.06Å; V366-S370 WeakPolarHBondContact O-CB 3.36Å; V366-S370 PolarHBondContact O-N 2.93Å; V366-S370 PolarHBondContact O-OG 3.12Å; V366-G389 VanDerWaalsContact CG1-O 3.31Å; V366-G389 WeakPolarHBondContact CG1-O 3.33Å; V366-F392 HydrophobicContact CG1-CD1 4.32Å
367	I	93.7	Very high	89.4	Confident	0 Å²	0	29.8 Å²	29.8	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-59.5	-48.6	175.9	-66.7	167.5	0	0	0	110	C301 P304 G363 L364 S370 S371 I394 V397	C301-I367 HydrophobicContact CB-CD1 3.53Å; P304-I367 HydrophobicContact CB-CG2 4.26Å; P304-I367 HydrophobicContact CG-CG2 3.74Å; G363-I367 VanDerWaalsContact O-CG1 3.25Å; G363-I367 WeakPolarHBondContact O-CG1 3.5Å; G363-I367 PolarHBondContact O-N 2.9Å; L364-I367 PolarHBondContact O-N 3.14Å; I367-S370 PolarHBondContact O-N 2.71Å; I367-S371 WeakPolarHBondContact O-CB 3.22Å; I367-S371 PolarHBondContact O-N 3.25Å; I367-S371 PolarHBondContact O-OG 3.12Å; I367-I394 HydrophobicContact CD1-CB 4.45Å; I367-I394 HydrophobicContact CD1-CG1 3.68Å; I367-I394 HydrophobicContact CG1-CG1 4.06Å; I367-V397 HydrophobicContact CD1-CG2 4.05Å
368	G	91.9	Very high	88.9	Confident	0 Å²	0	38.8 Å²	38.8	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-68.8	-38.8	-177.2	0	0	0	0	0	113	L364 A365 S371 C372 G456	L364-G368 PolarHBondContact O-N 2.82Å; A365-G368 PolarHBondContact O-N 3.38Å; G368-S371 PolarHBondContact O-N 3.42Å; G368-C372 PolarHBondContact O-N 3.16Å; G368-C372 VanDerWaalsContact O-N 3.07Å; G368-C372 PolarHBondContact O-SG 3Å; G368-G456 WeakPolarHBondContact CA-O 3.14Å
369	A	91.8	Very high	88.4	Confident	50 Å²	50	38.1 Å²	38.1	41%	0.413	22%	0.221	S	C	.	.	H	α-helix	trans	-61.3	-45.5	172.5	0	0	0	0	0	111.8	A365 V366 C372 I373	A365-A369 WeakPolarHBondContact O-CB 3.34Å; A365-A369 PolarHBondContact O-N 3.07Å; V366-A369 PolarHBondContact O-N 3.06Å; A369-C372 PolarHBondContact O-N 3.38Å; A369-I373 WeakPolarHBondContact O-CD1 3.45Å; A369-I373 VanDerWaalsContact O-CG1 3.3Å; A369-I373 WeakPolarHBondContact O-CG1 3.41Å; A369-I373 PolarHBondContact O-N 3.44Å
370	S	92.1	Very high	88	Confident	11 Å²	11	41 Å²	41	8%	0.077	23%	0.234	C	C	.	.	H	α-helix	trans	-63.8	-44.4	178.4	-53.8	0	0	0	0	111.1	V366 I367 C372 I373 V374 S386 G389 L390	V366-S370 WeakPolarHBondContact O-CB 3.36Å; V366-S370 PolarHBondContact O-N 2.93Å; V366-S370 PolarHBondContact O-OG 3.12Å; I367-S370 PolarHBondContact O-N 2.71Å; S370-C372 VanDerWaalsContact C-N 3.28Å; S370-C372 PolarHBondContact O-N 3.12Å; S370-I373 PolarHBondContact O-N 3.43Å; S370-V374 WeakPolarHBondContact O-CG2 3.17Å; S370-V374 PolarHBondContact O-N 3.16Å; S370-V374 VanDerWaalsContact O-N 3.16Å; S370-S386 PolarHBondContact O-OG 2.87Å; S370-G389 VanDerWaalsContact OG-C 3.27Å; S370-G389 WeakPolarHBondContact OG-CA 3.42Å; S370-L390 PolarHBondContact OG-N 3.11Å
371	S	88.7	Confident	87.8	Confident	1 Å²	1	44 Å²	44	1%	0.007	26%	0.259	C	S	.	.	H	α-helix	trans	-60.3	-35.4	177.7	-56.3	0	0	0	0	112.5	P304 I367 G368 I373 S452	P304-S371 WeakPolarHBondContact CB-OG 3.39Å; I367-S371 WeakPolarHBondContact O-CB 3.22Å; I367-S371 PolarHBondContact O-N 3.25Å; I367-S371 PolarHBondContact O-OG 3.12Å; G368-S371 PolarHBondContact O-N 3.42Å; S371-I373 VanDerWaalsContact C-N 3.32Å; S371-I373 PolarHBondContact O-N 2.87Å; S371-S452 PolarHBondContact O-OG 3.49Å
372	C	88.3	Confident	87.6	Confident	47 Å²	47	45.9 Å²	45.9	32%	0.318	27%	0.27	S	S	.	.	H	α-helix	trans	-71.1	-24.8	174.6	-67.4	0	0	0	0	113.4	G368 A369 S370 L453	G368-C372 PolarHBondContact O-N 3.16Å; G368-C372 VanDerWaalsContact O-N 3.07Å; G368-C372 PolarHBondContact O-SG 3Å; A369-C372 PolarHBondContact O-N 3.38Å; S370-C372 VanDerWaalsContact C-N 3.28Å; S370-C372 PolarHBondContact O-N 3.12Å; C372-L453 HydrophobicContact CB-CD2 3.91Å
373	I	87.6	Confident	87.3	Confident	90 Å²	90	41.2 Å²	41.2	46%	0.462	25%	0.245	S	C	.	.	H	α-helix	trans	-84.2	-27.9	-178.7	-66.7	163.8	0	0	0	111.8	A369 S370 S371 A376 C377	A369-I373 WeakPolarHBondContact O-CD1 3.45Å; A369-I373 VanDerWaalsContact O-CG1 3.3Å; A369-I373 WeakPolarHBondContact O-CG1 3.41Å; A369-I373 PolarHBondContact O-N 3.44Å; S370-I373 PolarHBondContact O-N 3.43Å; S371-I373 VanDerWaalsContact C-N 3.32Å; S371-I373 PolarHBondContact O-N 2.87Å; I373-A376 WeakPolarHBondContact O-CB 3.36Å; I373-A376 PolarHBondContact O-N 3.33Å; I373-C377 PolarHBondContact O-SG 2.9Å
374	V	85.5	Confident	87.1	Confident	0 Å²	0	42 Å²	42	0%	0	25%	0.25	C	C	.	.	G	3₁₀ helix	trans	-49.2	-49.7	-177.7	176.8	0	0	0	0	113.1	L308 S370 A376 C377 L383 S386 F448	L308-V374 HydrophobicContact CD1-CG2 4.19Å; L308-V374 HydrophobicContact CD2-CG1 3.9Å; S370-V374 WeakPolarHBondContact O-CG2 3.17Å; S370-V374 PolarHBondContact O-N 3.16Å; S370-V374 VanDerWaalsContact O-N 3.16Å; V374-A376 VanDerWaalsContact C-N 3.27Å; V374-A376 PolarHBondContact O-N 3.34Å; V374-C377 WeakPolarHBondContact O-CB 3.34Å; V374-C377 PolarHBondContact O-N 3.37Å; V374-L383 HydrophobicContact CG1-CD1 4.02Å; V374-S386 VanDerWaalsContact CG2-OG 3.31Å; V374-S386 WeakPolarHBondContact CG2-OG 3.49Å; V374-F448 HydrophobicContact CG1-CE1 4.04Å; V374-F448 HydrophobicContact CG1-CZ 3.97Å
375	P	81.6	Confident	87	Confident	20 Å²	20	46.9 Å²	46.9	13%	0.13	28%	0.279	C	S	.	.	G	3₁₀ helix	trans	-70.1	-22.5	-177.4	-14.5	29.3	0	0	0	113.9	C377 F448 E449	P375-C377 VanDerWaalsContact C-N 3.25Å; P375-C377 PolarHBondContact O-N 3.26Å; P375-F448 HydrophobicContact CB-CD1 4.22Å; P375-F448 HydrophobicContact CB-CE1 4.31Å; P375-F448 HydrophobicContact CG-CD1 4.38Å; P375-F448 HydrophobicContact CG-CE1 4.25Å; P375-E449 HydrophobicContact CB-CB 4.09Å; P375-E449 HydrophobicContact CB-CG 3.84Å
376	A	82.6	Confident	86.9	Confident	77 Å²	77	45.2 Å²	45.2	64%	0.636	27%	0.266	S	S	*	.	G	3₁₀ helix	trans	-77.9	-10.1	178.8	0	0	0	0	0	113	I373 V374 R378	I373-A376 WeakPolarHBondContact O-CB 3.36Å; I373-A376 PolarHBondContact O-N 3.33Å; V374-A376 VanDerWaalsContact C-N 3.27Å; V374-A376 PolarHBondContact O-N 3.34Å; A376-R378 PolarHBondContact O-N 3.31Å
377	C	80.5	Confident	86.7	Confident	5 Å²	5	43.5 Å²	43.5	3%	0.034	26%	0.255	C	S	.	.			trans	-78.3	108.6	-175.5	-65.6	0	0	0	0	111.4	W315 M320 I373 V374 P375 P382 L383	W315-C377 VanDerWaalsContact CH2-O 3.23Å; W315-C377 WeakPolarHBondContact CH2-O 3.05Å; M320-C377 VanDerWaalsContact CE-O 3.29Å; M320-C377 WeakPolarHBondContact CE-O 3.44Å; I373-C377 PolarHBondContact O-SG 2.9Å; V374-C377 WeakPolarHBondContact O-CB 3.34Å; V374-C377 PolarHBondContact O-N 3.37Å; P375-C377 VanDerWaalsContact C-N 3.25Å; P375-C377 PolarHBondContact O-N 3.26Å; C377-P382 HydrophobicContact CB-CB 4.19Å; C377-P382 VanDerWaalsContact SG-C 3.58Å; C377-L383 HydrophobicContact CB-CB 4.14Å; C377-L383 HydrophobicContact CB-CD1 4.38Å
378	R	76	Confident	86.6	Confident	231 Å²	231	44.5 Å²	44.5	87%	0.872	26%	0.262	S	S	*	.			trans	-95.3	3.7	176.8	-64.8	-169.8	176.8	172.4	-0.1	114.8	A376	A376-R378 PolarHBondContact O-N 3.31Å
379	S	79.9	Confident	86.6	Confident	61 Å²	61	45.4 Å²	45.4	43%	0.427	27%	0.271	S	S	.	.	S	Bend	trans	-142.7	161.9	178.3	52.9	0	0	0	0	111.4	M320 A381 P382 L383	M320-S379 WeakPolarHBondContact CE-O 3.22Å; S379-A381 PolarHBondContact O-N 3.46Å; S379-P382 WeakPolarHBondContact O-CD 3.42Å; S379-P382 WeakPolarHBondContact OG-CD 3.28Å; S379-P382 VanDerWaalsContact OG-CG 3.23Å; S379-P382 WeakPolarHBondContact OG-CG 3.01Å; S379-L383 PolarHBondContact O-N 2.98Å
380	F	80.9	Confident	86.7	Confident	78 Å²	78	43 Å²	43	34%	0.342	25%	0.251	S	S	.	.	H	α-helix	trans	-61.1	-43.6	-175.5	-175.8	-101.5	0	0	0	113.1	M316 E326 A330 L383 V384	M316-F380 HydrophobicContact CE-CE2 4.33Å; E326-F380 HydrophobicContact CB-CE2 4.48Å; A330-F380 HydrophobicContact CB-CE2 4.12Å; A330-F380 HydrophobicContact CB-CZ 4.48Å; F380-L383 WeakPolarHBondContact O-CB 3.44Å; F380-L383 PolarHBondContact O-N 3.23Å; F380-V384 HydrophobicContact CD1-CG2 4.14Å; F380-V384 HydrophobicContact CE1-CG2 3.79Å; F380-V384 HydrophobicContact CE2-CG2 4.33Å; F380-V384 HydrophobicContact CZ-CG2 3.9Å; F380-V384 WeakPolarHBondContact O-CG2 3.45Å; F380-V384 PolarHBondContact O-N 2.94Å
381	A	83.9	Confident	86.6	Confident	64 Å²	64	42.7 Å²	42.7	53%	0.529	25%	0.249	S	C	.	.	H	α-helix	trans	-65	-48.2	-176	0	0	0	0	0	113.9	S379 L383 V384 V385	S379-A381 PolarHBondContact O-N 3.46Å; A381-L383 VanDerWaalsContact C-N 3.29Å; A381-L383 PolarHBondContact O-N 3.42Å; A381-V384 PolarHBondContact O-N 3.47Å; A381-V385 WeakPolarHBondContact O-CG2 3.49Å; A381-V385 PolarHBondContact O-N 3.31Å
382	P	86.9	Confident	86.8	Confident	55 Å²	55	45 Å²	45	36%	0.357	26%	0.259	S	S	.	.	H	α-helix	trans	-60.1	-35.6	173.1	-25.9	35	0	0	0	113.9	C377 S379 V385 S386	C377-P382 HydrophobicContact CB-CB 4.19Å; C377-P382 VanDerWaalsContact SG-C 3.58Å; S379-P382 WeakPolarHBondContact O-CD 3.42Å; S379-P382 WeakPolarHBondContact OG-CD 3.28Å; S379-P382 VanDerWaalsContact OG-CG 3.23Å; S379-P382 WeakPolarHBondContact OG-CG 3.01Å; P382-V385 PolarHBondContact O-N 2.92Å; P382-S386 PolarHBondContact O-N 2.89Å
383	L	87.5	Confident	87	Confident	0 Å²	0	42.8 Å²	42.8	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-61.8	-49.1	176.2	-178.4	67.4	0	0	0	110.8	I312 W315 M316 M320 V374 C377 S379 F380 A381 V385 S386 L387	I312-L383 HydrophobicContact CD1-CD1 4.19Å; I312-L383 HydrophobicContact CD1-CD2 4.47Å; W315-L383 HydrophobicContact CH2-CD1 4.25Å; W315-L383 HydrophobicContact CZ3-CD1 3.7Å; W315-L383 HydrophobicContact CZ3-CD2 3.89Å; W315-L383 HydrophobicContact CZ3-CG 4.38Å; M316-L383 HydrophobicContact CG-CD2 3.67Å; M316-L383 HydrophobicContact SD-CD2 3.64Å; M320-L383 HydrophobicContact CE-CB 4.47Å; M320-L383 HydrophobicContact CE-CD2 4.4Å; M320-L383 HydrophobicContact SD-CD2 4.41Å; V374-L383 HydrophobicContact CG1-CD1 4.02Å; C377-L383 HydrophobicContact CB-CB 4.14Å; C377-L383 HydrophobicContact CB-CD1 4.38Å; S379-L383 PolarHBondContact O-N 2.98Å; F380-L383 WeakPolarHBondContact O-CB 3.44Å; F380-L383 PolarHBondContact O-N 3.23Å; A381-L383 VanDerWaalsContact C-N 3.29Å; A381-L383 PolarHBondContact O-N 3.42Å; L383-V385 VanDerWaalsContact C-N 3.31Å; L383-V385 PolarHBondContact O-N 3.2Å; L383-S386 WeakPolarHBondContact O-CB 3.34Å; L383-S386 PolarHBondContact O-N 3.27Å; L383-S386 VanDerWaalsContact O-N 3.12Å; L383-L387 HydrophobicContact CG-CD1 4.41Å; L383-L387 WeakPolarHBondContact O-CG 3.36Å; L383-L387 PolarHBondContact O-N 2.87Å
384	V	88.6	Confident	87.2	Confident	15 Å²	15	38.7 Å²	38.7	9%	0.091	22%	0.223	C	C	.	.	H	α-helix	trans	-58.4	-43.4	176.3	171.5	0	0	0	0	111	P333 F380 A381 S386 L387 C388	P333-V384 HydrophobicContact CB-CG1 3.5Å; P333-V384 VanDerWaalsContact CB-CG1 3.5Å; P333-V384 HydrophobicContact CG-CG1 3.7Å; F380-V384 HydrophobicContact CD1-CG2 4.14Å; F380-V384 HydrophobicContact CE1-CG2 3.79Å; F380-V384 HydrophobicContact CE2-CG2 4.33Å; F380-V384 HydrophobicContact CZ-CG2 3.9Å; F380-V384 WeakPolarHBondContact O-CG2 3.45Å; F380-V384 PolarHBondContact O-N 2.94Å; A381-V384 PolarHBondContact O-N 3.47Å; V384-S386 VanDerWaalsContact C-N 3.3Å; V384-S386 PolarHBondContact O-N 3.24Å; V384-L387 PolarHBondContact O-N 2.85Å; V384-C388 WeakPolarHBondContact O-CB 3.4Å; V384-C388 PolarHBondContact O-N 3.44Å; V384-C388 PolarHBondContact O-SG 3.23Å
385	V	91.2	Very high	87.4	Confident	103 Å²	103	38.8 Å²	38.8	62%	0.624	22%	0.223	S	C	*	.	H	α-helix	trans	-61.6	-39.2	176.9	172.3	0	0	0	0	111.8	A381 P382 L383 C388 G389	A381-V385 WeakPolarHBondContact O-CG2 3.49Å; A381-V385 PolarHBondContact O-N 3.31Å; P382-V385 PolarHBondContact O-N 2.92Å; L383-V385 VanDerWaalsContact C-N 3.31Å; L383-V385 PolarHBondContact O-N 3.2Å; V385-C388 WeakPolarHBondContact O-CB 3.31Å; V385-C388 PolarHBondContact O-N 3.39Å; V385-G389 PolarHBondContact O-N 2.98Å; V385-G389 VanDerWaalsContact O-N 3.07Å
386	S	91.1	Very high	87.9	Confident	5 Å²	5	38 Å²	38	4%	0.035	22%	0.218	C	C	.	.	H	α-helix	trans	-65.9	-43.9	176	-166.6	0	0	0	0	112	S370 V374 P382 L383 V384 C388 G389 L390	S370-S386 PolarHBondContact O-OG 2.87Å; V374-S386 VanDerWaalsContact CG2-OG 3.31Å; V374-S386 WeakPolarHBondContact CG2-OG 3.49Å; P382-S386 PolarHBondContact O-N 2.89Å; L383-S386 WeakPolarHBondContact O-CB 3.34Å; L383-S386 PolarHBondContact O-N 3.27Å; L383-S386 VanDerWaalsContact O-N 3.12Å; V384-S386 VanDerWaalsContact C-N 3.3Å; V384-S386 PolarHBondContact O-N 3.24Å; S386-C388 VanDerWaalsContact C-N 3.32Å; S386-C388 PolarHBondContact O-N 2.78Å; S386-G389 PolarHBondContact O-N 3.49Å; S386-G389 VanDerWaalsContact O-N 3.16Å; S386-L390 PolarHBondContact O-N 3.17Å
387	L	89.8	Confident	88.3	Confident	0 Å²	0	34.3 Å²	34.3	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-62.7	-38.7	175.4	-67.5	175.5	0	0	0	112.5	L308 I312 A330 W331 A334 L383 V384 L390 C391	L308-L387 HydrophobicContact CD1-CD2 4.39Å; I312-L387 HydrophobicContact CD1-CD1 3.75Å; I312-L387 HydrophobicContact CD1-CD2 3.65Å; I312-L387 HydrophobicContact CD1-CG 4.13Å; A330-L387 HydrophobicContact CB-CD1 4.26Å; W331-L387 HydrophobicContact CH2-CD2 4Å; W331-L387 HydrophobicContact CZ2-CD2 4.44Å; W331-L387 HydrophobicContact CZ3-CD2 4.16Å; A334-L387 HydrophobicContact CB-CB 4.49Å; L383-L387 HydrophobicContact CG-CD1 4.41Å; L383-L387 WeakPolarHBondContact O-CG 3.36Å; L383-L387 PolarHBondContact O-N 2.87Å; V384-L387 PolarHBondContact O-N 2.85Å; L387-L390 PolarHBondContact O-N 3.19Å; L387-C391 WeakPolarHBondContact O-CB 3.5Å; L387-C391 PolarHBondContact O-N 3.37Å; L387-C391 PolarHBondContact O-SG 3.46Å
388	C	91.8	Very high	88.7	Confident	22 Å²	22	35.2 Å²	35.2	15%	0.149	19%	0.192	C	C	.	.	H	α-helix	trans	-57.4	-46.7	171.9	-77	0	0	0	0	111.8	P337 V384 V385 S386 F392	P337-C388 HydrophobicContact CB-CB 4.31Å; P337-C388 HydrophobicContact CG-CB 3.66Å; V384-C388 WeakPolarHBondContact O-CB 3.4Å; V384-C388 PolarHBondContact O-N 3.44Å; V384-C388 PolarHBondContact O-SG 3.23Å; V385-C388 WeakPolarHBondContact O-CB 3.31Å; V385-C388 PolarHBondContact O-N 3.39Å; S386-C388 VanDerWaalsContact C-N 3.32Å; S386-C388 PolarHBondContact O-N 2.78Å; C388-F392 VanDerWaalsContact O-CB 3.28Å; C388-F392 WeakPolarHBondContact O-CB 3.41Å; C388-F392 PolarHBondContact O-N 3.37Å
389	G	92.6	Very high	89.2	Confident	18 Å²	18	25.5 Å²	25.5	19%	0.186	16%	0.159	C	C	.	.	H	α-helix	trans	-62.2	-44.3	175.9	0	0	0	0	0	112.2	V366 S370 V385 S386 F392 G393	V366-G389 VanDerWaalsContact CG1-O 3.31Å; V366-G389 WeakPolarHBondContact CG1-O 3.33Å; S370-G389 VanDerWaalsContact OG-C 3.27Å; S370-G389 WeakPolarHBondContact OG-CA 3.42Å; V385-G389 PolarHBondContact O-N 2.98Å; V385-G389 VanDerWaalsContact O-N 3.07Å; S386-G389 PolarHBondContact O-N 3.49Å; S386-G389 VanDerWaalsContact O-N 3.16Å; G389-F392 PolarHBondContact O-N 2.93Å; G389-G393 PolarHBondContact O-N 3.12Å
390	L	92.6	Very high	89.5	Confident	0 Å²	0	22.6 Å²	22.6	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-60.9	-49.8	177.8	-172.9	144.6	0	0	0	111.9	P304 L305 L308 S370 S386 L387 F392 G393 I394	P304-L390 HydrophobicContact CB-CD1 3.98Å; L305-L390 HydrophobicContact CB-CD2 4.26Å; L305-L390 HydrophobicContact CD1-CD2 4.13Å; L308-L390 HydrophobicContact CD1-CD1 3.43Å; L308-L390 VanDerWaalsContact CD1-CD1 3.43Å; S370-L390 PolarHBondContact OG-N 3.11Å; S386-L390 PolarHBondContact O-N 3.17Å; L387-L390 PolarHBondContact O-N 3.19Å; L390-F392 PolarHBondContact O-N 2.96Å; L390-G393 PolarHBondContact O-N 2.91Å; L390-I394 HydrophobicContact CD2-CD1 3.56Å; L390-I394 HydrophobicContact CG-CD1 4.39Å; L390-I394 WeakPolarHBondContact O-CG1 3.31Å; L390-I394 PolarHBondContact O-N 2.74Å
391	C	91.1	Very high	89.8	Confident	5 Å²	5	18.9 Å²	18.9	3%	0.034	12%	0.122	C	C	.	.	H	α-helix	trans	-67.8	-34.1	-179.8	-63.6	0	0	0	0	112.9	A334 H338 L387 A395	A334-C391 HydrophobicContact CB-CB 4.1Å; H338-C391 HydrophobicContact CB-CB 4.13Å; H338-C391 PolarHBondContact ND1-O 3.22Å; L387-C391 WeakPolarHBondContact O-CB 3.5Å; L387-C391 PolarHBondContact O-N 3.37Å; L387-C391 PolarHBondContact O-SG 3.46Å; C391-A395 WeakPolarHBondContact O-CB 3.09Å; C391-A395 PolarHBondContact O-N 2.94Å
392	F	93.4	Very high	89.9	Confident	49 Å²	49	16.5 Å²	16.5	22%	0.215	10%	0.101	C	C	.	.	H	α-helix	trans	-64.8	-42	172.4	176.5	-100.7	0	0	0	111.6	P337 G341 L344 V366 C388 G389 L390 A395 L396	P337-F392 HydrophobicContact CB-CB 3.97Å; P337-F392 WeakPolarHBondContact O-CD2 3.47Å; G341-F392 VanDerWaalsContact CA-CE2 3.49Å; L344-F392 HydrophobicContact CD2-CE2 4.3Å; L344-F392 HydrophobicContact CD2-CZ 3.96Å; V366-F392 HydrophobicContact CG1-CD1 4.32Å; C388-F392 VanDerWaalsContact O-CB 3.28Å; C388-F392 WeakPolarHBondContact O-CB 3.41Å; C388-F392 PolarHBondContact O-N 3.37Å; G389-F392 PolarHBondContact O-N 2.93Å; L390-F392 PolarHBondContact O-N 2.96Å; F392-A395 PolarHBondContact O-N 3.19Å; F392-L396 HydrophobicContact CD1-CD1 3.76Å; F392-L396 HydrophobicContact CE1-CD1 3.37Å; F392-L396 HydrophobicContact CE1-CG 4.32Å; F392-L396 HydrophobicContact CZ-CD1 3.9Å; F392-L396 HydrophobicContact CZ-CG 4.44Å; F392-L396 PolarHBondContact O-N 3.44Å; F392-L396 VanDerWaalsContact O-N 3.08Å
393	G	92.7	Very high	89.5	Confident	0 Å²	0	17 Å²	17	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-63.7	-43.3	175.9	0	0	0	0	0	112.6	G389 L390 L396 V397	G389-G393 PolarHBondContact O-N 3.12Å; L390-G393 PolarHBondContact O-N 2.91Å; G393-L396 WeakPolarHBondContact O-CB 3.5Å; G393-L396 PolarHBondContact O-N 3.25Å; G393-V397 WeakPolarHBondContact O-CG2 3.17Å; G393-V397 PolarHBondContact O-N 2.95Å; G393-V397 VanDerWaalsContact O-N 3.13Å
394	I	91.4	Very high	89.3	Confident	5 Å²	5	17.2 Å²	17.2	3%	0.026	11%	0.105	C	C	.	.	H	α-helix	trans	-61.5	-45.5	175.5	-68	172.2	0	0	0	110.7	L305 I367 L390 L396 V397 D398	L305-I394 HydrophobicContact CB-CD1 3.63Å; L305-I394 HydrophobicContact CD2-CD1 3.73Å; L305-I394 HydrophobicContact CG-CD1 4.15Å; I367-I394 HydrophobicContact CD1-CB 4.45Å; I367-I394 HydrophobicContact CD1-CG1 3.68Å; I367-I394 HydrophobicContact CG1-CG1 4.06Å; L390-I394 HydrophobicContact CD2-CD1 3.56Å; L390-I394 HydrophobicContact CG-CD1 4.39Å; L390-I394 WeakPolarHBondContact O-CG1 3.31Å; L390-I394 PolarHBondContact O-N 2.74Å; I394-L396 VanDerWaalsContact C-N 3.29Å; I394-L396 PolarHBondContact O-N 3.48Å; I394-V397 PolarHBondContact O-N 2.96Å; I394-V397 VanDerWaalsContact O-N 3.07Å; I394-D398 WeakPolarHBondContact CG2-OD2 3.09Å; I394-D398 PolarHBondContact O-N 3.38Å
395	A	90.1	Very high	89	Confident	1 Å²	1	16.5 Å²	16.5	1%	0.008	10%	0.101	C	C	.	.	H	α-helix	trans	-56.7	-41.3	176.1	0	0	0	0	0	113	H338 V342 C391 F392 T399	H338-A395 VanDerWaalsContact O-CB 3.28Å; H338-A395 WeakPolarHBondContact O-CB 3.35Å; V342-A395 HydrophobicContact CG2-CB 3.87Å; C391-A395 WeakPolarHBondContact O-CB 3.09Å; C391-A395 PolarHBondContact O-N 2.94Å; F392-A395 PolarHBondContact O-N 3.19Å; A395-T399 WeakPolarHBondContact O-CB 3.35Å; A395-T399 PolarHBondContact O-N 2.87Å; A395-T399 VanDerWaalsContact O-N 3.12Å; A395-T399 PolarHBondContact O-OG1 2.97Å
396	L	90.9	Very high	88.4	Confident	3 Å²	3	12.2 Å²	12.2	2%	0.016	8%	0.076	C	C	.	.	H	α-helix	trans	-60.9	-45	175.3	-80.9	160.1	0	0	0	111.7	T345 F392 G393 I394 A400	T345-L396 WeakPolarHBondContact OG1-CD2 2.93Å; F392-L396 HydrophobicContact CD1-CD1 3.76Å; F392-L396 HydrophobicContact CE1-CD1 3.37Å; F392-L396 HydrophobicContact CE1-CG 4.32Å; F392-L396 HydrophobicContact CZ-CD1 3.9Å; F392-L396 HydrophobicContact CZ-CG 4.44Å; F392-L396 PolarHBondContact O-N 3.44Å; F392-L396 VanDerWaalsContact O-N 3.08Å; G393-L396 WeakPolarHBondContact O-CB 3.5Å; G393-L396 PolarHBondContact O-N 3.25Å; I394-L396 VanDerWaalsContact C-N 3.29Å; I394-L396 PolarHBondContact O-N 3.48Å; L396-A400 WeakPolarHBondContact O-CB 3.28Å; L396-A400 PolarHBondContact O-N 3.41Å
397	V	91.5	Very high	87.7	Confident	0 Å²	0	15.2 Å²	15.2	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-68.3	-55.5	-178.3	-180	0	0	0	0	111	C301 L364 I367 G393 I394 T399 A400 L401	C301-V397 HydrophobicContact CB-CB 4.13Å; C301-V397 HydrophobicContact CB-CG1 3.86Å; C301-V397 HydrophobicContact CB-CG2 4.11Å; L364-V397 HydrophobicContact CD2-CG2 4.38Å; L364-V397 HydrophobicContact CG-CG2 4.12Å; I367-V397 HydrophobicContact CD1-CG2 4.05Å; G393-V397 WeakPolarHBondContact O-CG2 3.17Å; G393-V397 PolarHBondContact O-N 2.95Å; G393-V397 VanDerWaalsContact O-N 3.13Å; I394-V397 PolarHBondContact O-N 2.96Å; I394-V397 VanDerWaalsContact O-N 3.07Å; V397-T399 VanDerWaalsContact C-N 3.35Å; V397-T399 PolarHBondContact O-N 3.24Å; V397-A400 PolarHBondContact O-N 3.26Å; V397-L401 HydrophobicContact CG1-CD1 3.45Å; V397-L401 VanDerWaalsContact CG1-CD1 3.45Å; V397-L401 HydrophobicContact CG1-CG 4.05Å; V397-L401 VanDerWaalsContact O-CB 3.24Å; V397-L401 WeakPolarHBondContact O-CB 3.49Å; V397-L401 WeakPolarHBondContact O-CG 3.49Å; V397-L401 PolarHBondContact O-N 3.03Å
398	D	88.4	Confident	87.1	Confident	24 Å²	24	15.2 Å²	15.2	13%	0.128	9%	0.089	C	C	.	.	H	α-helix	trans	-61.2	-44.5	-175.5	-72.5	-33.6	0	0	0	111.6	L298 I394 A400 L402 Y428	L298-D398 WeakPolarHBondContact CD2-OD1 3.48Å; I394-D398 WeakPolarHBondContact CG2-OD2 3.09Å; I394-D398 PolarHBondContact O-N 3.38Å; D398-A400 VanDerWaalsContact C-N 3.32Å; D398-A400 PolarHBondContact O-N 3.23Å; D398-L402 WeakPolarHBondContact O-CB 3.39Å; D398-L402 VanDerWaalsContact O-CG 3.25Å; D398-L402 WeakPolarHBondContact O-CG 3.32Å; D398-L402 PolarHBondContact O-N 3.21Å; D398-L402 VanDerWaalsContact O-N 3.1Å; D398-Y428 WeakPolarHBondContact OD1-CE1 3.44Å; D398-Y428 PolarHBondContact OD1-OH 3.37Å
399	T	86.4	Confident	86.2	Confident	28 Å²	28	14.2 Å²	14.2	17%	0.172	8%	0.082	C	C	.	.	H	α-helix	trans	-68.2	-32.7	-179	-51.7	0	0	0	0	112.2	V342 T345 V346 A395 V397 P403	V342-T399 HydrophobicContact CG1-CG2 4.24Å; T345-T399 HydrophobicContact CG2-CG2 3.82Å; V346-T399 HydrophobicContact CG2-CG2 3.62Å; A395-T399 WeakPolarHBondContact O-CB 3.35Å; A395-T399 PolarHBondContact O-N 2.87Å; A395-T399 VanDerWaalsContact O-N 3.12Å; A395-T399 PolarHBondContact O-OG1 2.97Å; V397-T399 VanDerWaalsContact C-N 3.35Å; V397-T399 PolarHBondContact O-N 3.24Å; T399-P403 WeakPolarHBondContact O-CD 3.26Å; T399-P403 WeakPolarHBondContact O-CG 3.39Å
400	A	87.3	Confident	85.3	Confident	0 Å²	0	14.8 Å²	14.8	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-80.3	-41.2	178.6	0	0	0	0	0	112.3	T345 L396 V397 D398 T404	T345-A400 HydrophobicContact CG2-CB 3.95Å; L396-A400 WeakPolarHBondContact O-CB 3.28Å; L396-A400 PolarHBondContact O-N 3.41Å; V397-A400 PolarHBondContact O-N 3.26Å; D398-A400 VanDerWaalsContact C-N 3.32Å; D398-A400 PolarHBondContact O-N 3.23Å; A400-T404 PolarHBondContact O-OG1 3.05Å
401	L	87.4	Confident	84.3	Confident	0 Å²	0	15.6 Å²	15.6	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-87.2	-31.9	-168.6	-69.9	-169.5	0	0	0	114.3	V294 A297 L298 V397 T404 L405 L466 L469	V294-L401 HydrophobicContact CG1-CB 3.98Å; V294-L401 HydrophobicContact CG1-CD1 4.5Å; A297-L401 HydrophobicContact CB-CD1 3.43Å; A297-L401 VanDerWaalsContact CB-CD1 3.43Å; L298-L401 HydrophobicContact CD2-CB 3.99Å; L298-L401 HydrophobicContact CD2-CD1 4.31Å; L298-L401 HydrophobicContact CG-CB 4.4Å; L298-L401 HydrophobicContact CG-CD1 4.39Å; V397-L401 HydrophobicContact CG1-CD1 3.45Å; V397-L401 VanDerWaalsContact CG1-CD1 3.45Å; V397-L401 HydrophobicContact CG1-CG 4.05Å; V397-L401 VanDerWaalsContact O-CB 3.24Å; V397-L401 WeakPolarHBondContact O-CB 3.49Å; V397-L401 WeakPolarHBondContact O-CG 3.49Å; V397-L401 PolarHBondContact O-N 3.03Å; L401-T404 PolarHBondContact O-N 3.45Å; L401-L405 WeakPolarHBondContact O-CB 3.46Å; L401-L405 PolarHBondContact O-N 3.13Å; L401-L466 HydrophobicContact CD1-CD2 4.37Å; L401-L466 HydrophobicContact CD2-CD2 4.06Å; L401-L469 HydrophobicContact CD2-CD1 4.33Å
402	L	84.3	Confident	83.2	Confident	14 Å²	14	19.5 Å²	19.5	7%	0.073	10%	0.099	C	C	.	.	H	α-helix	trans	-61	-44.9	178.3	-70.6	172.4	0	0	0	112.6	L218 L298 D398 L405 A406 A424	L218-L402 HydrophobicContact CD1-CD1 4.12Å; L218-L402 HydrophobicContact CD2-CD1 4.24Å; L298-L402 HydrophobicContact CD1-CD2 4.13Å; D398-L402 WeakPolarHBondContact O-CB 3.39Å; D398-L402 VanDerWaalsContact O-CG 3.25Å; D398-L402 WeakPolarHBondContact O-CG 3.32Å; D398-L402 PolarHBondContact O-N 3.21Å; D398-L402 VanDerWaalsContact O-N 3.1Å; L402-L405 WeakPolarHBondContact O-CB 3.48Å; L402-L405 PolarHBondContact O-N 3.04Å; L402-A406 PolarHBondContact O-N 3.32Å; L402-A406 VanDerWaalsContact O-N 3.13Å; L402-A424 HydrophobicContact CD2-CB 3.5Å; L402-A424 VanDerWaalsContact CD2-CB 3.5Å
403	P	80.1	Confident	82.3	Confident	64 Å²	64	19.8 Å²	19.8	42%	0.416	10%	0.101	S	C	.	.	H	α-helix	trans	-65.2	-37.2	173.2	-22	34.9	0	0	0	112.9	T399 L405 A406 F407	T399-P403 WeakPolarHBondContact O-CD 3.26Å; T399-P403 WeakPolarHBondContact O-CG 3.39Å; P403-L405 VanDerWaalsContact C-N 3.32Å; P403-L405 PolarHBondContact O-N 3.31Å; P403-A406 PolarHBondContact O-N 3.03Å; P403-F407 WeakPolarHBondContact O-CB 3.39Å; P403-F407 PolarHBondContact O-N 2.68Å
404	T	81.5	Confident	80.9	Confident	5 Å²	5	24.4 Å²	24.4	3%	0.031	13%	0.129	C	C	.	.	H	α-helix	trans	-63.6	-39.4	176.1	-52.6	0	0	0	0	111.3	V294 Q356 A400 L401 F407 L408 V472	V294-T404 HydrophobicContact CG2-CG2 4.49Å; Q356-T404 PolarHBondContact OE1-OG1 2.86Å; A400-T404 PolarHBondContact O-OG1 3.05Å; L401-T404 PolarHBondContact O-N 3.45Å; T404-F407 PolarHBondContact O-N 3.35Å; T404-L408 VanDerWaalsContact O-CB 3.25Å; T404-L408 WeakPolarHBondContact O-CB 3.16Å; T404-L408 PolarHBondContact O-N 3.49Å; T404-V472 HydrophobicContact CG2-CG1 4.21Å
405	L	83.1	Confident	79.2	Confident	0 Å²	0	26 Å²	26	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-60.4	-48.3	175	-171	66.3	0	0	0	110.9	I291 V294 L298 L401 L402 P403 L408 V409 V420 I423 A424	I291-L405 HydrophobicContact CG2-CD1 3.8Å; V294-L405 HydrophobicContact CB-CD1 4.04Å; V294-L405 HydrophobicContact CG1-CB 3.9Å; V294-L405 HydrophobicContact CG1-CD1 3.88Å; V294-L405 HydrophobicContact CG1-CG 4.37Å; L298-L405 HydrophobicContact CD1-CD2 4.42Å; L401-L405 WeakPolarHBondContact O-CB 3.46Å; L401-L405 PolarHBondContact O-N 3.13Å; L402-L405 WeakPolarHBondContact O-CB 3.48Å; L402-L405 PolarHBondContact O-N 3.04Å; P403-L405 VanDerWaalsContact C-N 3.32Å; P403-L405 PolarHBondContact O-N 3.31Å; L405-L408 PolarHBondContact O-N 2.85Å; L405-V409 WeakPolarHBondContact O-CG2 3.45Å; L405-V409 PolarHBondContact O-N 3.09Å; L405-V409 VanDerWaalsContact O-N 3.11Å; L405-V420 HydrophobicContact CB-CG1 4.26Å; L405-V420 HydrophobicContact CD2-CG1 4.01Å; L405-V420 WeakPolarHBondContact CD2-O 3.38Å; L405-V420 HydrophobicContact CG-CG1 3.82Å; L405-I423 HydrophobicContact CD1-CG2 4.42Å; L405-I423 HydrophobicContact CD2-CB 4.46Å; L405-I423 HydrophobicContact CD2-CG2 4.37Å; L405-A424 HydrophobicContact CD2-CB 4.07Å
406	A	77.8	Confident	78	Confident	13 Å²	13	28 Å²	28	11%	0.107	15%	0.153	C	C	.	.	H	α-helix	trans	-60.6	-48.3	177.7	0	0	0	0	0	112	L402 P403 L408 V409 D410 V420	L402-A406 PolarHBondContact O-N 3.32Å; L402-A406 VanDerWaalsContact O-N 3.13Å; P403-A406 PolarHBondContact O-N 3.03Å; A406-L408 VanDerWaalsContact C-N 3.32Å; A406-L408 PolarHBondContact O-N 3.43Å; A406-V409 PolarHBondContact O-N 3.32Å; A406-D410 WeakPolarHBondContact O-CB 3.39Å; A406-D410 VanDerWaalsContact O-CG 3.31Å; A406-D410 PolarHBondContact O-N 2.73Å; A406-V420 VanDerWaalsContact CA-CG1 3.49Å; A406-V420 HydrophobicContact CB-CG1 3.92Å
407	F	77.3	Confident	76.7	Confident	69 Å²	69	29.7 Å²	29.7	30%	0.303	16%	0.159	S	C	.	.	H	α-helix	trans	-58.7	-43.6	177.7	176.2	-102.2	0	0	0	112.3	P403 T404 V409 D410 V411 V472 L475	P403-F407 WeakPolarHBondContact O-CB 3.39Å; P403-F407 PolarHBondContact O-N 2.68Å; T404-F407 PolarHBondContact O-N 3.35Å; F407-V409 PolarHBondContact O-N 2.79Å; F407-D410 PolarHBondContact O-N 3.15Å; F407-V411 HydrophobicContact CD1-CG2 4.3Å; F407-V411 HydrophobicContact CD2-CG2 4.23Å; F407-V411 HydrophobicContact CE1-CG2 3.91Å; F407-V411 HydrophobicContact CE2-CG2 3.83Å; F407-V411 HydrophobicContact CG-CG2 4.45Å; F407-V411 HydrophobicContact CZ-CG2 3.66Å; F407-V411 VanDerWaalsContact O-CG2 3.23Å; F407-V411 WeakPolarHBondContact O-CG2 3.48Å; F407-V411 PolarHBondContact O-N 2.98Å; F407-V472 HydrophobicContact CD1-CG1 3.9Å; F407-V472 HydrophobicContact CE1-CG1 3.98Å; F407-L475 HydrophobicContact CE1-CB 4.47Å
408	L	76.6	Confident	75.4	Confident	0 Å²	0	30.4 Å²	30.4	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-67.1	-38	-177.5	-175	66.3	0	0	0	112.5	I291 T404 L405 A406 R412 L475	I291-L408 HydrophobicContact CB-CD2 4.27Å; I291-L408 HydrophobicContact CG1-CD2 3.48Å; I291-L408 VanDerWaalsContact CG1-CD2 3.48Å; I291-L408 HydrophobicContact CG1-CG 3.92Å; I291-L408 VanDerWaalsContact N-CD2 3.35Å; T404-L408 VanDerWaalsContact O-CB 3.25Å; T404-L408 WeakPolarHBondContact O-CB 3.16Å; T404-L408 PolarHBondContact O-N 3.49Å; L405-L408 PolarHBondContact O-N 2.85Å; A406-L408 VanDerWaalsContact C-N 3.32Å; A406-L408 PolarHBondContact O-N 3.43Å; L408-R412 HydrophobicContact CD1-CG 4.47Å; L408-R412 WeakPolarHBondContact O-CB 3.38Å; L408-R412 PolarHBondContact O-N 3.41Å; L408-L475 HydrophobicContact CD1-CD1 4.24Å
409	V	74.3	Confident	74.5	Confident	0 Å²	0	29.8 Å²	29.8	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-68.4	-43.1	174.8	178.3	0	0	0	0	110.5	L285 I291 L405 A406 F407 V411 R412 H413 V420	L285-V409 HydrophobicContact CD2-CG1 3.61Å; L285-V409 HydrophobicContact CD2-CG2 4Å; I291-V409 HydrophobicContact CD1-CG2 3.65Å; I291-V409 HydrophobicContact CG1-CG2 4.31Å; L405-V409 WeakPolarHBondContact O-CG2 3.45Å; L405-V409 PolarHBondContact O-N 3.09Å; L405-V409 VanDerWaalsContact O-N 3.11Å; A406-V409 PolarHBondContact O-N 3.32Å; F407-V409 PolarHBondContact O-N 2.79Å; V409-V411 VanDerWaalsContact C-N 3.29Å; V409-V411 PolarHBondContact O-N 2.73Å; V409-R412 PolarHBondContact O-N 3.47Å; V409-H413 HydrophobicContact CG1-CB 4.48Å; V409-H413 CarbonylContact O-C 3.54Å; V409-H413 PolarHBondContact O-N 2.91Å; V409-V420 HydrophobicContact CB-CG2 3.74Å; V409-V420 HydrophobicContact CG1-CG2 3.76Å; V409-V420 HydrophobicContact CG2-CG2 3.99Å
410	D	72.8	Confident	73.9	Confident	31 Å²	31	28.6 Å²	28.6	17%	0.166	16%	0.157	C	C	.	.	H	α-helix	trans	-60.5	-35.5	176.9	-74.6	-6.7	0	0	0	112.6	A406 F407 S415 Y417	A406-D410 WeakPolarHBondContact O-CB 3.39Å; A406-D410 VanDerWaalsContact O-CG 3.31Å; A406-D410 PolarHBondContact O-N 2.73Å; F407-D410 PolarHBondContact O-N 3.15Å; D410-S415 WeakPolarHBondContact OD1-CB 3.47Å; D410-S415 PolarHBondContact OD1-OG 2.93Å; D410-Y417 PolarHBondContact OD2-OH 3.39Å
411	V	71.1	Confident	73.3	Confident	16 Å²	16	30 Å²	30	10%	0.097	16%	0.163	C	C	.	.	H	α-helix	trans	-78.1	-36.5	-179.1	171.7	0	0	0	0	112.4	F407 V409 L475 S478	F407-V411 HydrophobicContact CD1-CG2 4.3Å; F407-V411 HydrophobicContact CD2-CG2 4.23Å; F407-V411 HydrophobicContact CE1-CG2 3.91Å; F407-V411 HydrophobicContact CE2-CG2 3.83Å; F407-V411 HydrophobicContact CG-CG2 4.45Å; F407-V411 HydrophobicContact CZ-CG2 3.66Å; F407-V411 VanDerWaalsContact O-CG2 3.23Å; F407-V411 WeakPolarHBondContact O-CG2 3.48Å; F407-V411 PolarHBondContact O-N 2.98Å; V409-V411 VanDerWaalsContact C-N 3.29Å; V409-V411 PolarHBondContact O-N 2.73Å; V411-L475 HydrophobicContact CG1-CB 4.24Å; V411-S478 WeakPolarHBondContact O-CB 3.34Å
412	R	68.4	Low	72.9	Confident	87 Å²	87	30.2 Å²	30.2	33%	0.328	16%	0.164	S	C	.	.	H	α-helix	trans	-104.5	-20.6	-167.7	-68	-170.1	168.1	-160	-1.4	114.8	D288 Y290 L408 V409	D288-R412 VanDerWaalsContact CG-NH1 3.33Å; D288-R412 IonicContact OD1-CZ 3.19Å; D288-R412 IonicContact OD1-NH1 3.3Å; D288-R412 PolarHBondContact OD1-NH1 3.09Å; D288-R412 WeakPolarHBondContact OD2-CD 3.39Å; D288-R412 IonicContact OD2-CZ 3.6Å; D288-R412 IonicContact OD2-NE 2.92Å; D288-R412 IonicContact OD2-NH1 3.99Å; D288-R412 PolarHBondContact OD2-NH1 3.13Å; Y290-R412 VanDerWaalsContact CD2-CZ 3.45Å; L408-R412 HydrophobicContact CD1-CG 4.47Å; L408-R412 WeakPolarHBondContact O-CB 3.38Å; L408-R412 PolarHBondContact O-N 3.41Å; V409-R412 PolarHBondContact O-N 3.47Å
413	H	73.9	Confident	72.8	Confident	55 Å²	55	29.6 Å²	29.6	26%	0.255	16%	0.161	S	C	.	.	S	Bend	trans	-139.7	164.5	-172.2	-63.8	-78	0	0	0	110.6	T280 D288 V409 S415	T280-H413 HydrophobicContact CG2-CB 4.23Å; D288-H413 IonicContact OD2-NE2 3.15Å; V409-H413 HydrophobicContact CG1-CB 4.48Å; V409-H413 CarbonylContact O-C 3.54Å; V409-H413 PolarHBondContact O-N 2.91Å; H413-S415 PolarHBondContact O-N 3.45Å
414	V	63.9	Low	72.9	Confident	98 Å²	98	26.6 Å²	26.6	59%	0.594	14%	0.142	S	C	*	.			trans	-74.1	100.5	168.7	-178.2	0	0	0	0	107.2	T280	T280-V414 PolarHBondContact OG1-O 3.25Å
415	S	55.9	Low	73	Confident	37 Å²	37	27.5 Å²	27.5	26%	0.259	15%	0.146	S	C	.	.			trans	-78.2	134.5	-172.7	64.1	0	0	0	0	112.1	D410 H413	D410-S415 WeakPolarHBondContact OD1-CB 3.47Å; D410-S415 PolarHBondContact OD1-OG 2.93Å; H413-S415 PolarHBondContact O-N 3.45Å
416	V	64.9	Low	73.2	Confident	43 Å²	43	28 Å²	28	26%	0.261	15%	0.149	S	C	.	.			trans	-114.4	121	158.8	175.8	0	0	0	0	104.3	G418 S419	V416-G418 PolarHBondContact O-N 3.33Å; V416-S419 PolarHBondContact O-N 3.27Å; V416-S419 PolarHBondContact O-OG 3.4Å
417	Y	63.9	Low	73.7	Confident	39 Å²	39	27.5 Å²	27.5	15%	0.153	15%	0.145	C	C	.	.	H	α-helix	trans	-53.8	-32.1	-175.8	-76.2	-77.6	0	0	0	112.6	A201 R210 D410 S419 V420 Y421	A201-Y417 HydrophobicContact CB-CD2 4.3Å; A201-Y417 HydrophobicContact CB-CG 4.2Å; R210-Y417 VanDerWaalsContact NH2-CZ 3.27Å; R210-Y417 PolarHBondContact NH2-OH 2.95Å; D410-Y417 PolarHBondContact OD2-OH 3.39Å; Y417-S419 VanDerWaalsContact C-N 3.29Å; Y417-S419 PolarHBondContact O-N 2.83Å; Y417-V420 PolarHBondContact O-N 3.31Å; Y417-Y421 VanDerWaalsContact O-CD2 3.3Å; Y417-Y421 WeakPolarHBondContact O-CD2 3.45Å; Y417-Y421 PolarHBondContact O-N 3.04Å
418	G	64.8	Low	74.3	Confident	15 Å²	15	26.3 Å²	26.3	16%	0.155	14%	0.138	C	C	.	.	H	α-helix	trans	-56.4	-36.2	172.2	0	0	0	0	0	114.4	V416 A422	V416-G418 PolarHBondContact O-N 3.33Å; G418-A422 VanDerWaalsContact O-CB 3.24Å; G418-A422 WeakPolarHBondContact O-CB 3.3Å; G418-A422 PolarHBondContact O-N 3.03Å
419	S	69.7	Low	74.8	Confident	12 Å²	12	26.4 Å²	26.4	8%	0.084	14%	0.139	C	C	.	.	H	α-helix	trans	-75	-34.2	179.2	67.4	0	0	0	0	112.9	V416 Y417 A422 I423	V416-S419 PolarHBondContact O-N 3.27Å; V416-S419 PolarHBondContact O-OG 3.4Å; Y417-S419 VanDerWaalsContact C-N 3.29Å; Y417-S419 PolarHBondContact O-N 2.83Å; S419-A422 PolarHBondContact O-N 3.16Å; S419-I423 WeakPolarHBondContact O-CG1 3.25Å; S419-I423 PolarHBondContact O-N 3.18Å; S419-I423 VanDerWaalsContact O-N 3.12Å
420	V	73.6	Confident	75.7	Confident	2 Å²	2	28.4 Å²	28.4	1%	0.012	15%	0.151	C	C	.	.	H	α-helix	trans	-60.1	-51.4	173.7	-177.5	0	0	0	0	110.4	L405 A406 V409 Y417 I423 A424	L405-V420 HydrophobicContact CB-CG1 4.26Å; L405-V420 HydrophobicContact CD2-CG1 4.01Å; L405-V420 WeakPolarHBondContact CD2-O 3.38Å; L405-V420 HydrophobicContact CG-CG1 3.82Å; A406-V420 VanDerWaalsContact CA-CG1 3.49Å; A406-V420 HydrophobicContact CB-CG1 3.92Å; V409-V420 HydrophobicContact CB-CG2 3.74Å; V409-V420 HydrophobicContact CG1-CG2 3.76Å; V409-V420 HydrophobicContact CG2-CG2 3.99Å; Y417-V420 PolarHBondContact O-N 3.31Å; V420-I423 WeakPolarHBondContact O-CB 3.33Å; V420-I423 PolarHBondContact O-N 3.3Å; V420-A424 PolarHBondContact O-N 2.95Å
421	Y	74.8	Confident	76.5	Confident	31 Å²	31	27 Å²	27	12%	0.122	14%	0.143	C	C	.	.	H	α-helix	trans	-72.7	-29.8	-178.7	-75.7	-80.7	0	0	0	112.3	I197 L214 L218 Y417 I423 A424 D425	I197-Y421 HydrophobicContact CD1-CD1 3.97Å; I197-Y421 HydrophobicContact CD1-CG 4.09Å; I197-Y421 HydrophobicContact CG2-CD1 4.18Å; I197-Y421 HydrophobicContact CG2-CD2 3.36Å; I197-Y421 HydrophobicContact CG2-CE2 3.82Å; I197-Y421 HydrophobicContact CG2-CG 3.58Å; L214-Y421 HydrophobicContact CD1-CE2 4.19Å; L214-Y421 HydrophobicContact CD2-CE2 4.31Å; L218-Y421 HydrophobicContact CD1-CE1 4.41Å; L218-Y421 HydrophobicContact CD2-CE1 4.33Å; Y417-Y421 VanDerWaalsContact O-CD2 3.3Å; Y417-Y421 WeakPolarHBondContact O-CD2 3.45Å; Y417-Y421 PolarHBondContact O-N 3.04Å; Y421-I423 VanDerWaalsContact C-N 3.28Å; Y421-I423 PolarHBondContact O-N 3.12Å; Y421-A424 PolarHBondContact O-N 3.07Å; Y421-D425 WeakPolarHBondContact O-CB 3.47Å; Y421-D425 PolarHBondContact O-N 2.73Å
422	A	77.7	Confident	77.3	Confident	4 Å²	4	27.8 Å²	27.8	3%	0.033	15%	0.145	C	C	.	.	H	α-helix	trans	-61.4	-36	170.2	0	0	0	0	0	112.2	T194 I282 G418 S419 D425 I426	T194-A422 HydrophobicContact CG2-CB 4.4Å; I282-A422 HydrophobicContact CD1-CB 4.04Å; G418-A422 VanDerWaalsContact O-CB 3.24Å; G418-A422 WeakPolarHBondContact O-CB 3.3Å; G418-A422 PolarHBondContact O-N 3.03Å; S419-A422 PolarHBondContact O-N 3.16Å; A422-D425 PolarHBondContact O-N 3.42Å; A422-I426 WeakPolarHBondContact O-CB 3.19Å; A422-I426 WeakPolarHBondContact O-CD1 3.17Å; A422-I426 WeakPolarHBondContact O-CG1 3.25Å; A422-I426 PolarHBondContact O-N 2.97Å
423	I	82.3	Confident	78.3	Confident	0 Å²	0	24 Å²	24	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-65.9	-44.1	174.6	-66.7	164.2	0	0	0	110.8	I282 L285 M286 I291 A295 L405 S419 V420 Y421 D425 I426 S427	I282-I423 HydrophobicContact CG2-CG1 4.02Å; L285-I423 HydrophobicContact CB-CD1 3.55Å; L285-I423 HydrophobicContact CD2-CD1 3.73Å; L285-I423 HydrophobicContact CG-CD1 4.31Å; M286-I423 HydrophobicContact CG-CG1 4.18Å; I291-I423 HydrophobicContact CG2-CD1 4.02Å; I291-I423 HydrophobicContact CG2-CG2 4.26Å; A295-I423 HydrophobicContact CB-CG2 3.94Å; L405-I423 HydrophobicContact CD1-CG2 4.42Å; L405-I423 HydrophobicContact CD2-CB 4.46Å; L405-I423 HydrophobicContact CD2-CG2 4.37Å; S419-I423 WeakPolarHBondContact O-CG1 3.25Å; S419-I423 PolarHBondContact O-N 3.18Å; S419-I423 VanDerWaalsContact O-N 3.12Å; V420-I423 WeakPolarHBondContact O-CB 3.33Å; V420-I423 PolarHBondContact O-N 3.3Å; Y421-I423 VanDerWaalsContact C-N 3.28Å; Y421-I423 PolarHBondContact O-N 3.12Å; I423-D425 VanDerWaalsContact C-N 3.33Å; I423-D425 PolarHBondContact O-N 2.89Å; I423-I426 PolarHBondContact O-N 2.93Å; I423-S427 PolarHBondContact O-N 3.35Å; I423-S427 PolarHBondContact O-OG 2.99Å
424	A	82.8	Confident	78.9	Confident	2 Å²	2	25.7 Å²	25.7	2%	0.017	14%	0.143	C	C	.	.	H	α-helix	trans	-60.7	-43.5	175.3	0	0	0	0	0	111.6	L298 L402 L405 V420 Y421 I426 S427 Y428	L298-A424 HydrophobicContact CD1-CB 4.15Å; L402-A424 HydrophobicContact CD2-CB 3.5Å; L402-A424 VanDerWaalsContact CD2-CB 3.5Å; L405-A424 HydrophobicContact CD2-CB 4.07Å; V420-A424 PolarHBondContact O-N 2.95Å; Y421-A424 PolarHBondContact O-N 3.07Å; A424-I426 PolarHBondContact O-N 3.46Å; A424-S427 VanDerWaalsContact O-CB 3.29Å; A424-S427 WeakPolarHBondContact O-CB 3.07Å; A424-S427 PolarHBondContact O-N 2.95Å; A424-S427 VanDerWaalsContact O-N 3.13Å; A424-Y428 HydrophobicContact CB-CE2 4.35Å; A424-Y428 VanDerWaalsContact O-CD2 3.29Å; A424-Y428 WeakPolarHBondContact O-CD2 3.48Å; A424-Y428 PolarHBondContact O-N 3.37Å
425	D	83.1	Confident	79.9	Confident	23 Å²	23	21.2 Å²	21.2	12%	0.123	12%	0.116	C	C	.	.	H	α-helix	trans	-68.1	-35.8	179.3	-163.6	50.7	0	0	0	112.8	Q135 N139 Y421 A422 I423 S427 Y428 S429	Q135-D425 PolarHBondContact NE2-OD1 2.92Å; Q135-D425 VanDerWaalsContact NE2-OD1 3.17Å; Q135-D425 PolarHBondContact NE2-OD2 3.48Å; N139-D425 PolarHBondContact ND2-OD2 3.17Å; N139-D425 PolarHBondContact OD1-OD2 2.93Å; Y421-D425 WeakPolarHBondContact O-CB 3.47Å; Y421-D425 PolarHBondContact O-N 2.73Å; A422-D425 PolarHBondContact O-N 3.42Å; I423-D425 VanDerWaalsContact C-N 3.33Å; I423-D425 PolarHBondContact O-N 2.89Å; D425-S427 VanDerWaalsContact C-N 3.34Å; D425-Y428 PolarHBondContact O-N 3.43Å; D425-S429 VanDerWaalsContact O-CB 3.27Å; D425-S429 WeakPolarHBondContact O-CB 3.2Å; D425-S429 PolarHBondContact O-N 2.8Å; D425-S429 PolarHBondContact O-OG 3.42Å
426	I	87.3	Confident	81.2	Confident	11 Å²	11	19.5 Å²	19.5	6%	0.056	10%	0.104	C	C	.	.	H	α-helix	trans	-59.5	-45.4	168.9	-74.9	165.2	0	0	0	110.4	L136 N139 P140 I282 M286 A422 I423 A424 S429 V430	L136-I426 HydrophobicContact CD1-CB 4.27Å; L136-I426 HydrophobicContact CD1-CG1 4.32Å; L136-I426 HydrophobicContact CD1-CG2 3.71Å; N139-I426 HydrophobicContact CB-CD1 4.37Å; N139-I426 HydrophobicContact CB-CG1 3.88Å; P140-I426 HydrophobicContact CG-CD1 4.39Å; I282-I426 HydrophobicContact CG2-CD1 4.18Å; M286-I426 HydrophobicContact CE-CG2 4.01Å; M286-I426 HydrophobicContact SD-CD1 4.39Å; M286-I426 HydrophobicContact SD-CG2 4.43Å; A422-I426 WeakPolarHBondContact O-CB 3.19Å; A422-I426 WeakPolarHBondContact O-CD1 3.17Å; A422-I426 WeakPolarHBondContact O-CG1 3.25Å; A422-I426 PolarHBondContact O-N 2.97Å; I423-I426 PolarHBondContact O-N 2.93Å; A424-I426 PolarHBondContact O-N 3.46Å; I426-S429 PolarHBondContact O-N 3.46Å; I426-V430 VanDerWaalsContact O-CG2 3.31Å; I426-V430 WeakPolarHBondContact O-CG2 3.35Å; I426-V430 PolarHBondContact O-N 3.42Å
427	S	89.7	Confident	81.9	Confident	3 Å²	3	21.1 Å²	21.1	2%	0.021	11%	0.111	C	C	.	.	H	α-helix	trans	-59.6	-45.9	176.5	-70.6	0	0	0	0	112.6	A295 T299 I423 A424 D425 V430 A431	A295-S427 VanDerWaalsContact CA-OG 3.28Å; A295-S427 WeakPolarHBondContact CA-OG 3.44Å; A295-S427 WeakPolarHBondContact CB-OG 3.42Å; A295-S427 WeakPolarHBondContact O-CB 3.39Å; A295-S427 PolarHBondContact O-OG 3.36Å; T299-S427 WeakPolarHBondContact OG1-CB 3.37Å; T299-S427 PolarHBondContact OG1-O 3.24Å; I423-S427 PolarHBondContact O-N 3.35Å; I423-S427 PolarHBondContact O-OG 2.99Å; A424-S427 VanDerWaalsContact O-CB 3.29Å; A424-S427 WeakPolarHBondContact O-CB 3.07Å; A424-S427 PolarHBondContact O-N 2.95Å; A424-S427 VanDerWaalsContact O-N 3.13Å; D425-S427 VanDerWaalsContact C-N 3.34Å; S427-V430 PolarHBondContact O-N 2.88Å; S427-A431 PolarHBondContact O-N 3.39Å
428	Y	88.5	Confident	82.7	Confident	44 Å²	44	21.9 Å²	21.9	17%	0.173	12%	0.119	C	C	.	.	H	α-helix	trans	-62.3	-46.3	175.4	-61	-37.6	0	0	0	111.2	L298 N302 D398 A424 D425 V430 A431 Y432	L298-Y428 HydrophobicContact CB-CE1 4.36Å; L298-Y428 HydrophobicContact CD2-CE1 4.31Å; N302-Y428 VanDerWaalsContact ND2-CD1 3.32Å; N302-Y428 WeakPolarHBondContact ND2-CD1 3.43Å; N302-Y428 WeakPolarHBondContact ND2-CE1 3.27Å; D398-Y428 WeakPolarHBondContact OD1-CE1 3.44Å; D398-Y428 PolarHBondContact OD1-OH 3.37Å; A424-Y428 HydrophobicContact CB-CE2 4.35Å; A424-Y428 VanDerWaalsContact O-CD2 3.29Å; A424-Y428 WeakPolarHBondContact O-CD2 3.48Å; A424-Y428 PolarHBondContact O-N 3.37Å; D425-Y428 PolarHBondContact O-N 3.43Å; Y428-V430 VanDerWaalsContact C-N 3.3Å; Y428-V430 PolarHBondContact O-N 3.1Å; Y428-A431 WeakPolarHBondContact O-CB 3.25Å; Y428-A431 PolarHBondContact O-N 2.72Å; Y428-A431 VanDerWaalsContact O-N 3.11Å; Y428-Y432 WeakPolarHBondContact O-CD2 3.45Å; Y428-Y432 PolarHBondContact O-N 2.94Å
429	S	88.7	Confident	83	Confident	2 Å²	2	21.3 Å²	21.3	1%	0.014	11%	0.113	C	C	.	.	H	α-helix	trans	-60.7	-37.6	178.9	-61.9	0	0	0	0	112.5	Q135 D425 I426 Y432 A433	Q135-S429 WeakPolarHBondContact CG-OG 3.19Å; D425-S429 VanDerWaalsContact O-CB 3.27Å; D425-S429 WeakPolarHBondContact O-CB 3.2Å; D425-S429 PolarHBondContact O-N 2.8Å; D425-S429 PolarHBondContact O-OG 3.42Å; I426-S429 PolarHBondContact O-N 3.46Å; S429-Y432 PolarHBondContact O-N 3.03Å; S429-A433 WeakPolarHBondContact O-CB 3.32Å; S429-A433 PolarHBondContact O-N 2.98Å
430	V	91.3	Very high	82.9	Confident	42 Å²	42	21 Å²	21	26%	0.255	11%	0.112	S	C	.	.	H	α-helix	trans	-63.4	-45.3	174.4	170.9	0	0	0	0	110.9	L136 T299 I426 S427 Y428 A433 L434	L136-V430 HydrophobicContact CD1-CG2 3.82Å; L136-V430 HydrophobicContact CD2-CG2 3.93Å; T299-V430 HydrophobicContact CG2-CB 4.08Å; T299-V430 HydrophobicContact CG2-CG1 3.71Å; I426-V430 VanDerWaalsContact O-CG2 3.31Å; I426-V430 WeakPolarHBondContact O-CG2 3.35Å; I426-V430 PolarHBondContact O-N 3.42Å; S427-V430 PolarHBondContact O-N 2.88Å; Y428-V430 VanDerWaalsContact C-N 3.3Å; Y428-V430 PolarHBondContact O-N 3.1Å; V430-A433 PolarHBondContact O-N 3.09Å; V430-L434 HydrophobicContact CG1-CD1 3.8Å; V430-L434 HydrophobicContact CG1-CG 4.45Å; V430-L434 WeakPolarHBondContact O-CB 3.32Å; V430-L434 WeakPolarHBondContact O-CG 3.36Å; V430-L434 PolarHBondContact O-N 3.14Å
431	A	90.4	Very high	82.8	Confident	0 Å²	0	27.7 Å²	27.7	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-61.7	-46.9	177.7	0	0	0	0	0	111.6	T299 N302 I303 A306 S427 Y428 A433 L434 G435	T299-A431 HydrophobicContact CG2-CB 4.16Å; T299-A431 WeakPolarHBondContact O-CB 3.27Å; N302-A431 HydrophobicContact CB-CB 3.78Å; I303-A431 HydrophobicContact CG1-CB 4.03Å; A306-A431 WeakPolarHBondContact CB-O 3.43Å; S427-A431 PolarHBondContact O-N 3.39Å; Y428-A431 WeakPolarHBondContact O-CB 3.25Å; Y428-A431 PolarHBondContact O-N 2.72Å; Y428-A431 VanDerWaalsContact O-N 3.11Å; A431-A433 PolarHBondContact O-N 3.35Å; A431-L434 PolarHBondContact O-N 3.42Å; A431-G435 WeakPolarHBondContact O-CA 3.46Å; A431-G435 PolarHBondContact O-N 2.84Å
432	Y	87.7	Confident	82.5	Confident	33 Å²	33	28.4 Å²	28.4	13%	0.129	15%	0.148	C	C	.	.	H	α-helix	trans	-75.6	-19.2	-179.1	-71.7	-64.8	0	0	0	114.5	Y50 L305 A306 Y428 S429 P436	Y50-Y432 AromaticContact CE1-CD1 3.75Å; Y50-Y432 HydrophobicContact CE1-CD1 3.75Å; Y50-Y432 AromaticContact CE1-CE1 3.61Å; Y50-Y432 HydrophobicContact CE1-CE1 3.61Å; Y50-Y432 HydrophobicContact CE1-CG 4.4Å; Y50-Y432 AromaticContact CZ-CD1 3.59Å; Y50-Y432 AromaticContact CZ-CE1 3.97Å; Y50-Y432 WeakPolarHBondContact OH-CD1 3.2Å; L305-Y432 WeakPolarHBondContact CD2-OH 3.33Å; A306-Y432 HydrophobicContact CB-CD1 3.34Å; A306-Y432 HydrophobicContact CB-CE1 3.74Å; A306-Y432 HydrophobicContact CB-CG 4.12Å; Y428-Y432 WeakPolarHBondContact O-CD2 3.45Å; Y428-Y432 PolarHBondContact O-N 2.94Å; S429-Y432 PolarHBondContact O-N 3.03Å; Y432-P436 WeakPolarHBondContact O-CD 3.3Å; Y432-P436 WeakPolarHBondContact O-CG 3.44Å
433	A	89.8	Confident	81.9	Confident	7 Å²	7	30 Å²	30	6%	0.058	16%	0.158	C	C	.	.	H	α-helix	trans	-79.1	-44.9	170.4	0	0	0	0	0	111.2	A129 A132 I133 S429 V430 A431 I437	A129-A433 WeakPolarHBondContact CB-O 3.47Å; A132-A433 HydrophobicContact CB-CB 3.96Å; I133-A433 HydrophobicContact CG1-CB 3.79Å; S429-A433 WeakPolarHBondContact O-CB 3.32Å; S429-A433 PolarHBondContact O-N 2.98Å; V430-A433 PolarHBondContact O-N 3.09Å; A431-A433 PolarHBondContact O-N 3.35Å; A433-I437 WeakPolarHBondContact O-CD1 3.29Å; A433-I437 WeakPolarHBondContact O-CG1 3.46Å
434	L	87	Confident	80.9	Confident	92 Å²	92	33.8 Å²	33.8	48%	0.482	18%	0.175	S	C	.	.	H	α-helix	trans	-75.2	-40.8	-178.1	-67.6	176.1	0	0	0	112.1	V430 A431 I437 V438	V430-L434 HydrophobicContact CG1-CD1 3.8Å; V430-L434 HydrophobicContact CG1-CG 4.45Å; V430-L434 WeakPolarHBondContact O-CB 3.32Å; V430-L434 WeakPolarHBondContact O-CG 3.36Å; V430-L434 PolarHBondContact O-N 3.14Å; A431-L434 PolarHBondContact O-N 3.42Å; L434-I437 PolarHBondContact O-N 3.1Å; L434-V438 VanDerWaalsContact O-CB 3.25Å; L434-V438 WeakPolarHBondContact O-CB 3.43Å; L434-V438 WeakPolarHBondContact O-CG2 3.49Å; L434-V438 PolarHBondContact O-N 3.37Å
435	G	84.3	Confident	80.1	Confident	4 Å²	4	37.4 Å²	37.4	4%	0.041	20%	0.2	C	C	.	.	H	α-helix	trans	-50.7	-62.5	-173.9	0	0	0	0	0	113.1	A431 I437 V438 A439	A431-G435 WeakPolarHBondContact O-CA 3.46Å; A431-G435 PolarHBondContact O-N 2.84Å; G435-I437 PolarHBondContact O-N 3.49Å; G435-V438 PolarHBondContact O-N 3.38Å; G435-A439 WeakPolarHBondContact O-CB 3.5Å; G435-A439 PolarHBondContact O-N 3.33Å
436	P	82.6	Confident	79.2	Confident	0 Å²	0	40.6 Å²	40.6	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-65.9	-32	-178	-23.9	35.2	0	0	0	115	G125 F128 A129 P310 Y432 A439 G440	G125-P436 VanDerWaalsContact O-CB 3.25Å; G125-P436 WeakPolarHBondContact O-CB 3.44Å; F128-P436 HydrophobicContact CB-CB 3.9Å; F128-P436 HydrophobicContact CB-CG 3.83Å; A129-P436 HydrophobicContact CB-CB 4.43Å; P310-P436 HydrophobicContact CG-CB 4.28Å; P310-P436 HydrophobicContact CG-CG 4.36Å; Y432-P436 WeakPolarHBondContact O-CD 3.3Å; Y432-P436 WeakPolarHBondContact O-CG 3.44Å; P436-A439 WeakPolarHBondContact O-CB 3.16Å; P436-A439 PolarHBondContact O-N 2.99Å; P436-G440 PolarHBondContact O-N 3.2Å
437	I	81.1	Confident	78.5	Confident	77 Å²	77	41.5 Å²	41.5	40%	0.395	23%	0.229	S	C	.	.	H	α-helix	trans	-69.8	-49.3	178.1	-66.7	175.6	0	0	0	110.2	A129 I133 A433 L434 G435 A439 G440 H441	A129-I437 HydrophobicContact CB-CD1 3.74Å; A129-I437 HydrophobicContact CB-CG1 3.57Å; I133-I437 HydrophobicContact CD1-CD1 4.03Å; A433-I437 WeakPolarHBondContact O-CD1 3.29Å; A433-I437 WeakPolarHBondContact O-CG1 3.46Å; L434-I437 PolarHBondContact O-N 3.1Å; G435-I437 PolarHBondContact O-N 3.49Å; I437-A439 PolarHBondContact O-N 2.95Å; I437-G440 PolarHBondContact O-N 3.49Å; I437-H441 PolarHBondContact O-N 3.11Å
438	V	79.7	Confident	77.8	Confident	55 Å²	55	42.3 Å²	42.3	33%	0.333	23%	0.232	S	C	.	.	H	α-helix	trans	-63.2	-38.5	176	176.1	0	0	0	0	109.3	L434 G435 H441 I442 L451	L434-V438 VanDerWaalsContact O-CB 3.25Å; L434-V438 WeakPolarHBondContact O-CB 3.43Å; L434-V438 WeakPolarHBondContact O-CG2 3.49Å; L434-V438 PolarHBondContact O-N 3.37Å; G435-V438 PolarHBondContact O-N 3.38Å; V438-H441 PolarHBondContact O-N 3.4Å; V438-I442 HydrophobicContact CG1-CB 4.46Å; V438-I442 HydrophobicContact CG1-CD1 3.39Å; V438-I442 HydrophobicContact CG1-CG1 3.93Å; V438-I442 WeakPolarHBondContact O-CB 3.25Å; V438-I442 WeakPolarHBondContact O-CG1 3.24Å; V438-I442 PolarHBondContact O-N 3.33Å; V438-L451 HydrophobicContact CG1-CD1 4.22Å
439	A	71.9	Confident	77.4	Confident	3 Å²	3	46.5 Å²	46.5	3%	0.025	25%	0.253	C	S	.	.	H	α-helix	trans	-57.3	-55.4	175.7	0	0	0	0	0	112.4	F307 T311 G435 P436 I437 H441 V443	F307-A439 HydrophobicContact CD2-CB 3.28Å; F307-A439 HydrophobicContact CE2-CB 3.37Å; F307-A439 HydrophobicContact CG-CB 4.42Å; T311-A439 HydrophobicContact CG2-CB 3.76Å; G435-A439 WeakPolarHBondContact O-CB 3.5Å; G435-A439 PolarHBondContact O-N 3.33Å; P436-A439 WeakPolarHBondContact O-CB 3.16Å; P436-A439 PolarHBondContact O-N 2.99Å; I437-A439 PolarHBondContact O-N 2.95Å; A439-H441 VanDerWaalsContact C-N 3.29Å; A439-H441 PolarHBondContact O-N 3.45Å; A439-V443 WeakPolarHBondContact O-CB 3.31Å; A439-V443 WeakPolarHBondContact O-CG2 3.32Å; A439-V443 PolarHBondContact O-N 3.06Å
440	G	67.9	Low	77	Confident	7 Å²	7	51.9 Å²	51.9	7%	0.072	28%	0.278	C	S	.	.	H	α-helix	trans	-59.7	-39.1	-176.9	0	0	0	0	0	112.4	P436 I437 H444	P436-G440 PolarHBondContact O-N 3.2Å; I437-G440 PolarHBondContact O-N 3.49Å; G440-H444 PolarHBondContact O-CD2 2.85Å
441	H	70.1	Confident	76.4	Confident	142 Å²	142	50.5 Å²	50.5	66%	0.657	27%	0.269	S	S	*	.	H	α-helix	trans	-83.8	-40.4	-177.7	-162.6	65.9	0	0	0	113.7	I437 V438 A439 S445	I437-H441 PolarHBondContact O-N 3.11Å; V438-H441 PolarHBondContact O-N 3.4Å; A439-H441 VanDerWaalsContact C-N 3.29Å; A439-H441 PolarHBondContact O-N 3.45Å; H441-S445 PolarHBondContact O-N 3.4Å; H441-S445 PolarHBondContact O-OG 2.71Å
442	I	68.3	Low	76.1	Confident	45 Å²	45	50.5 Å²	50.5	23%	0.231	27%	0.269	C	S	.	.	H	α-helix	trans	-82	-34.1	-173.1	-61.6	-168.1	0	0	0	112.1	V438 H444 S445 L446 G447 L451	V438-I442 HydrophobicContact CG1-CB 4.46Å; V438-I442 HydrophobicContact CG1-CD1 3.39Å; V438-I442 HydrophobicContact CG1-CG1 3.93Å; V438-I442 WeakPolarHBondContact O-CB 3.25Å; V438-I442 WeakPolarHBondContact O-CG1 3.24Å; V438-I442 PolarHBondContact O-N 3.33Å; I442-H444 PolarHBondContact O-N 3.46Å; I442-S445 WeakPolarHBondContact CA-OG 3.24Å; I442-S445 PolarHBondContact O-N 3.35Å; I442-S445 PolarHBondContact O-OG 3.09Å; I442-L446 HydrophobicContact CG2-CB 3.87Å; I442-L446 HydrophobicContact CG2-CD1 3.6Å; I442-L446 HydrophobicContact CG2-CG 4.32Å; I442-L446 PolarHBondContact O-N 3.43Å; I442-G447 PolarHBondContact O-N 3.01Å; I442-L451 HydrophobicContact CB-CD1 4.14Å; I442-L451 HydrophobicContact CB-CD2 3.79Å; I442-L451 HydrophobicContact CB-CG 4.49Å; I442-L451 HydrophobicContact CD1-CD1 4.3Å; I442-L451 HydrophobicContact CG2-CB 4.01Å; I442-L451 HydrophobicContact CG2-CD1 3.78Å; I442-L451 HydrophobicContact CG2-CD2 3.8Å; I442-L451 HydrophobicContact CG2-CG 4.08Å
443	V	65.7	Low	76	Confident	39 Å²	39	53.2 Å²	53.2	24%	0.236	29%	0.286	C	S	.	.	H	α-helix	trans	-58	-36.4	176	171.5	0	0	0	0	111.2	F307 T311 A439 G447 L451	F307-V443 HydrophobicContact CE2-CG2 3.67Å; F307-V443 HydrophobicContact CZ-CG2 3.72Å; T311-V443 HydrophobicContact CG2-CG2 4.23Å; A439-V443 WeakPolarHBondContact O-CB 3.31Å; A439-V443 WeakPolarHBondContact O-CG2 3.32Å; A439-V443 PolarHBondContact O-N 3.06Å; V443-G447 VanDerWaalsContact O-CA 3.27Å; V443-G447 WeakPolarHBondContact O-CA 3.47Å; V443-G447 PolarHBondContact O-N 3.3Å; V443-L451 HydrophobicContact CG2-CD2 3.7Å
444	H	61.5	Low	75.8	Confident	78 Å²	78	54.7 Å²	54.7	36%	0.361	30%	0.302	S	S	.	.	H	α-helix	trans	-74.7	-35.2	177.9	-71.5	-53.5	0	0	0	114.2	D121 G440 I442	D121-H444 WeakPolarHBondContact CB-NE2 3.18Å; D121-H444 IonicContact OD2-CE1 3.09Å; D121-H444 PolarHBondContact OD2-CE1 2.91Å; D121-H444 IonicContact OD2-NE2 3.93Å; D121-H444 PolarHBondContact OD2-NE2 3.46Å; G440-H444 PolarHBondContact O-CD2 2.85Å; I442-H444 PolarHBondContact O-N 3.46Å
445	S	65.6	Low	75.8	Confident	78 Å²	78	51 Å²	51	55%	0.545	28%	0.283	S	S	.	.	H	α-helix	trans	-90.7	-39.6	-173.3	49.6	0	0	0	0	114	H441 I442	H441-S445 PolarHBondContact O-N 3.4Å; H441-S445 PolarHBondContact O-OG 2.71Å; I442-S445 WeakPolarHBondContact CA-OG 3.24Å; I442-S445 PolarHBondContact O-N 3.35Å; I442-S445 PolarHBondContact O-OG 3.09Å
446	L	64.4	Low	76	Confident	91 Å²	91	50.9 Å²	50.9	48%	0.476	28%	0.281	S	S	.	.	H	α-helix	trans	-114.5	-11	-172.7	-72.8	147.4	0	0	0	112.7	I442 Q450	I442-L446 HydrophobicContact CG2-CB 3.87Å; I442-L446 HydrophobicContact CG2-CD1 3.6Å; I442-L446 HydrophobicContact CG2-CG 4.32Å; I442-L446 PolarHBondContact O-N 3.43Å; L446-Q450 HydrophobicContact CB-CB 4.31Å; L446-Q450 WeakPolarHBondContact O-CB 3.11Å; L446-Q450 VanDerWaalsContact O-CG 3.27Å; L446-Q450 WeakPolarHBondContact O-CG 3.21Å; L446-Q450 PolarHBondContact O-OE1 3.39Å
447	G	72.8	Confident	76.3	Confident	30 Å²	30	55.7 Å²	55.7	31%	0.309	31%	0.306	S	S	.	.	H	α-helix	trans	82.2	153.1	-177.4	0	0	0	0	0	113.3	I442 V443 E449 Q450 L451	I442-G447 PolarHBondContact O-N 3.01Å; V443-G447 VanDerWaalsContact O-CA 3.27Å; V443-G447 WeakPolarHBondContact O-CA 3.47Å; V443-G447 PolarHBondContact O-N 3.3Å; G447-E449 VanDerWaalsContact C-N 3.25Å; G447-E449 PolarHBondContact O-N 2.99Å; G447-Q450 PolarHBondContact O-N 3.49Å; G447-L451 PolarHBondContact O-N 3.39Å
448	F	75.3	Confident	76.7	Confident	19 Å²	19	54.1 Å²	54.1	8%	0.083	31%	0.305	C	S	.	.	H	α-helix	trans	-56.3	-36.8	-178.6	-178.9	-98.9	0	0	0	113.1	F307 L308 W315 V374 P375 S452	F307-F448 HydrophobicContact CE1-CD2 4.02Å; F307-F448 AromaticContact CE1-CE2 3.61Å; F307-F448 HydrophobicContact CE1-CE2 3.61Å; F307-F448 HydrophobicContact CE1-CZ 4.42Å; F307-F448 AromaticContact CZ-CD2 3.82Å; F307-F448 HydrophobicContact CZ-CD2 3.82Å; F307-F448 AromaticContact CZ-CE2 3.87Å; F307-F448 HydrophobicContact CZ-CE2 3.87Å; L308-F448 HydrophobicContact CD2-CE2 4.23Å; L308-F448 HydrophobicContact CD2-CZ 3.87Å; W315-F448 AromaticContact CD1-CD1 3.88Å; W315-F448 HydrophobicContact CD2-CE1 4.22Å; W315-F448 HydrophobicContact CG-CD1 4.4Å; W315-F448 HydrophobicContact CG-CE1 4.27Å; W315-F448 HydrophobicContact CG-CZ 4.39Å; W315-F448 AromaticContact NE1-CD1 3.81Å; V374-F448 HydrophobicContact CG1-CE1 4.04Å; V374-F448 HydrophobicContact CG1-CZ 3.97Å; P375-F448 HydrophobicContact CB-CD1 4.22Å; P375-F448 HydrophobicContact CB-CE1 4.31Å; P375-F448 HydrophobicContact CG-CD1 4.38Å; P375-F448 HydrophobicContact CG-CE1 4.25Å; F448-S452 WeakPolarHBondContact O-CB 3.35Å; F448-S452 PolarHBondContact O-N 3.37Å
449	E	78.8	Confident	77.3	Confident	132 Å²	132	51.6 Å²	51.6	62%	0.617	29%	0.289	S	S	*	.	H	α-helix	trans	-64.3	-47.6	-177.9	-55.9	-175	172.5	0	0	112.7	P375 G447 L451 S452 L453	P375-E449 HydrophobicContact CB-CB 4.09Å; P375-E449 HydrophobicContact CB-CG 3.84Å; G447-E449 VanDerWaalsContact C-N 3.25Å; G447-E449 PolarHBondContact O-N 2.99Å; E449-L451 VanDerWaalsContact C-N 3.33Å; E449-L451 PolarHBondContact O-N 2.99Å; E449-S452 PolarHBondContact O-N 3.31Å; E449-L453 WeakPolarHBondContact O-CB 3.19Å; E449-L453 WeakPolarHBondContact O-CG 3.48Å; E449-L453 PolarHBondContact O-N 3.26Å
450	Q	80.4	Confident	78.1	Confident	115 Å²	115	55.4 Å²	55.4	54%	0.537	31%	0.309	S	S	.	.	H	α-helix	trans	-68.5	-35.6	-177	-63.3	-173.4	7.9	0	0	111.7	L446 G447 G454	L446-Q450 HydrophobicContact CB-CB 4.31Å; L446-Q450 WeakPolarHBondContact O-CB 3.11Å; L446-Q450 VanDerWaalsContact O-CG 3.27Å; L446-Q450 WeakPolarHBondContact O-CG 3.21Å; L446-Q450 PolarHBondContact O-OE1 3.39Å; G447-Q450 PolarHBondContact O-N 3.49Å; Q450-G454 PolarHBondContact O-N 3.29Å
451	L	79.6	Confident	79.2	Confident	13 Å²	13	60.4 Å²	60.4	7%	0.068	33%	0.333	C	S	.	.	H	α-helix	trans	-69.8	-43.9	178	-177.3	52.1	0	0	0	112.1	F307 V438 I442 V443 G447 E449 L453 G454 M455	F307-L451 HydrophobicContact CD2-CD2 3.7Å; F307-L451 HydrophobicContact CD2-CG 4.13Å; F307-L451 HydrophobicContact CE2-CD2 3Å; F307-L451 HydrophobicContact CE2-CG 3.71Å; F307-L451 HydrophobicContact CZ-CB 4.49Å; F307-L451 HydrophobicContact CZ-CD2 3.47Å; F307-L451 VanDerWaalsContact CZ-CD2 3.47Å; F307-L451 HydrophobicContact CZ-CG 3.88Å; V438-L451 HydrophobicContact CG1-CD1 4.22Å; I442-L451 HydrophobicContact CB-CD1 4.14Å; I442-L451 HydrophobicContact CB-CD2 3.79Å; I442-L451 HydrophobicContact CB-CG 4.49Å; I442-L451 HydrophobicContact CD1-CD1 4.3Å; I442-L451 HydrophobicContact CG2-CB 4.01Å; I442-L451 HydrophobicContact CG2-CD1 3.78Å; I442-L451 HydrophobicContact CG2-CD2 3.8Å; I442-L451 HydrophobicContact CG2-CG 4.08Å; V443-L451 HydrophobicContact CG2-CD2 3.7Å; G447-L451 PolarHBondContact O-N 3.39Å; E449-L451 VanDerWaalsContact C-N 3.33Å; E449-L451 PolarHBondContact O-N 2.99Å; L451-L453 VanDerWaalsContact C-N 3.33Å; L451-L453 PolarHBondContact O-N 3.23Å; L451-G454 PolarHBondContact O-N 3.03Å; L451-M455 HydrophobicContact CD1-CG 4.48Å; L451-M455 HydrophobicContact CG-CE 4.23Å; L451-M455 WeakPolarHBondContact O-CE 3.49Å; L451-M455 WeakPolarHBondContact O-CG 3.19Å; L451-M455 PolarHBondContact O-N 2.86Å
452	S	83.1	Confident	80.2	Confident	0 Å²	0	56.1 Å²	56.1	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-61.1	-42.2	175.4	-154.9	0	0	0	0	111.9	S371 F448 E449 G456	S371-S452 PolarHBondContact O-OG 3.49Å; F448-S452 WeakPolarHBondContact O-CB 3.35Å; F448-S452 PolarHBondContact O-N 3.37Å; E449-S452 PolarHBondContact O-N 3.31Å; S452-G456 PolarHBondContact O-N 2.95Å
453	L	85.1	Confident	81.2	Confident	90 Å²	90	54.6 Å²	54.6	47%	0.471	31%	0.306	S	S	.	.	H	α-helix	trans	-64	-40.9	173.4	-74.2	169.2	0	0	0	112.1	C372 E449 L451 G456 L457	C372-L453 HydrophobicContact CB-CD2 3.91Å; E449-L453 WeakPolarHBondContact O-CB 3.19Å; E449-L453 WeakPolarHBondContact O-CG 3.48Å; E449-L453 PolarHBondContact O-N 3.26Å; L451-L453 VanDerWaalsContact C-N 3.33Å; L451-L453 PolarHBondContact O-N 3.23Å; L453-G456 PolarHBondContact O-N 2.96Å; L453-L457 WeakPolarHBondContact O-CB 3.24Å; L453-L457 PolarHBondContact O-N 3.49Å
454	G	85.8	Confident	82.3	Confident	39 Å²	39	56.2 Å²	56.2	40%	0.402	32%	0.317	S	S	.	.	H	α-helix	trans	-61.5	-45.5	178.2	0	0	0	0	0	113.1	Q450 L451 L457 A458	Q450-G454 PolarHBondContact O-N 3.29Å; L451-G454 PolarHBondContact O-N 3.03Å; G454-L457 PolarHBondContact O-N 3.28Å; G454-A458 WeakPolarHBondContact O-CB 3.01Å; G454-A458 PolarHBondContact O-N 3.28Å
455	M	87.6	Confident	83.5	Confident	15 Å²	15	54.8 Å²	54.8	7%	0.074	31%	0.314	C	S	.	.	H	α-helix	trans	-70.3	-35	176.5	-60.6	177.7	-68.9	0	0	112.3	I303 P304 F307 L451 A458 N459	I303-M455 HydrophobicContact CG2-CB 4.48Å; I303-M455 HydrophobicContact CG2-CG 3.94Å; I303-M455 HydrophobicContact CG2-SD 3.78Å; P304-M455 HydrophobicContact CG-CB 4.29Å; F307-M455 HydrophobicContact CB-CE 3.79Å; F307-M455 HydrophobicContact CB-SD 3.43Å; F307-M455 WeakPolarHBondContact CB-SD 3.12Å; F307-M455 HydrophobicContact CD1-CE 3.04Å; F307-M455 HydrophobicContact CD1-SD 3.93Å; F307-M455 HydrophobicContact CD2-CE 4.07Å; F307-M455 HydrophobicContact CD2-SD 4.22Å; F307-M455 HydrophobicContact CE1-CE 3.58Å; F307-M455 HydrophobicContact CG-CE 3.32Å; F307-M455 HydrophobicContact CG-SD 3.56Å; F307-M455 VanDerWaalsContact CG-SD 3.56Å; F307-M455 HydrophobicContact CZ-CE 4.34Å; L451-M455 HydrophobicContact CD1-CG 4.48Å; L451-M455 HydrophobicContact CG-CE 4.23Å; L451-M455 WeakPolarHBondContact O-CE 3.49Å; L451-M455 WeakPolarHBondContact O-CG 3.19Å; L451-M455 PolarHBondContact O-N 2.86Å; M455-A458 PolarHBondContact O-N 3.16Å; M455-N459 PolarHBondContact O-N 3.32Å; M455-N459 VanDerWaalsContact O-N 3.09Å; M455-N459 PolarHBondContact O-ND2 2.65Å
456	G	87.6	Confident	84.4	Confident	0 Å²	0	51 Å²	51	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-62.1	-44.6	173.7	0	0	0	0	0	111.8	G368 S452 L453 N459 L460	G368-G456 WeakPolarHBondContact CA-O 3.14Å; S452-G456 PolarHBondContact O-N 2.95Å; L453-G456 PolarHBondContact O-N 2.96Å; G456-N459 PolarHBondContact O-N 3.26Å; G456-L460 VanDerWaalsContact O-CD1 3.31Å; G456-L460 WeakPolarHBondContact O-CD1 3.23Å; G456-L460 PolarHBondContact O-N 3.07Å; G456-L460 VanDerWaalsContact O-N 3.1Å
457	L	90.2	Very high	85.2	Confident	101 Å²	101	51.1 Å²	51.1	53%	0.529	29%	0.288	S	S	.	.	H	α-helix	trans	-63.5	-43.1	174.9	-175.5	65.9	0	0	0	111.9	L453 G454 N459 L460 L461	L453-L457 WeakPolarHBondContact O-CB 3.24Å; L453-L457 PolarHBondContact O-N 3.49Å; G454-L457 PolarHBondContact O-N 3.28Å; L457-N459 VanDerWaalsContact C-N 3.29Å; L457-N459 PolarHBondContact O-N 3.25Å; L457-L460 PolarHBondContact O-N 3.21Å; L457-L461 HydrophobicContact CD1-CD1 4.32Å; L457-L461 HydrophobicContact CD1-CG 4.23Å; L457-L461 HydrophobicContact CD2-CD1 4.35Å; L457-L461 HydrophobicContact CG-CD1 3.85Å; L457-L461 HydrophobicContact CG-CG 4.19Å; L457-L461 WeakPolarHBondContact O-CB 3.44Å; L457-L461 VanDerWaalsContact O-CG 3.27Å; L457-L461 WeakPolarHBondContact O-CG 3.38Å; L457-L461 PolarHBondContact O-N 3.03Å
458	A	90	Very high	85.5	Confident	45 Å²	45	54.7 Å²	54.7	37%	0.372	30%	0.3	S	S	.	.	H	α-helix	trans	-57.9	-41.8	176.7	0	0	0	0	0	112.1	G454 M455 L461 Y462	G454-A458 WeakPolarHBondContact O-CB 3.01Å; G454-A458 PolarHBondContact O-N 3.28Å; M455-A458 PolarHBondContact O-N 3.16Å; A458-L461 PolarHBondContact O-N 3.35Å; A458-Y462 WeakPolarHBondContact O-CB 3.36Å; A458-Y462 PolarHBondContact O-N 3.4Å
459	N	90.7	Very high	85.6	Confident	1 Å²	1	54 Å²	54	1%	0.005	30%	0.297	C	S	.	.	H	α-helix	trans	-64.8	-43.7	175.1	-84.7	-75.8	0	0	0	112.7	T300 C301 P304 L364 M455 G456 L457 L461 Y462 A463	T300-N459 PolarHBondContact O-ND2 3.46Å; T300-N459 PolarHBondContact O-OD1 3.17Å; C301-N459 WeakPolarHBondContact CA-OD1 3.38Å; P304-N459 WeakPolarHBondContact CG-ND2 3.3Å; L364-N459 WeakPolarHBondContact CD2-OD1 3.47Å; M455-N459 PolarHBondContact O-N 3.32Å; M455-N459 VanDerWaalsContact O-N 3.09Å; M455-N459 PolarHBondContact O-ND2 2.65Å; G456-N459 PolarHBondContact O-N 3.26Å; L457-N459 VanDerWaalsContact C-N 3.29Å; L457-N459 PolarHBondContact O-N 3.25Å; N459-L461 VanDerWaalsContact C-N 3.34Å; N459-L461 PolarHBondContact O-N 3.41Å; N459-Y462 PolarHBondContact O-N 3.06Å; N459-A463 PolarHBondContact O-N 2.82Å; N459-A463 VanDerWaalsContact O-N 3.11Å
460	L	90.6	Very high	85.4	Confident	83 Å²	83	55.5 Å²	55.5	44%	0.435	30%	0.297	S	S	.	.	H	α-helix	trans	-63.9	-39.2	175.7	-95.6	78.1	0	0	0	112.2	G456 L457 Y462 A463 P464	G456-L460 VanDerWaalsContact O-CD1 3.31Å; G456-L460 WeakPolarHBondContact O-CD1 3.23Å; G456-L460 PolarHBondContact O-N 3.07Å; G456-L460 VanDerWaalsContact O-N 3.1Å; L457-L460 PolarHBondContact O-N 3.21Å; L460-Y462 VanDerWaalsContact C-N 3.32Å; L460-A463 WeakPolarHBondContact O-CB 3.29Å; L460-A463 PolarHBondContact O-N 3.46Å; L460-P464 VanDerWaalsContact O-CD 3.25Å; L460-P464 WeakPolarHBondContact O-CD 3.23Å
461	L	90.8	Very high	84.7	Confident	113 Å²	113	54.5 Å²	54.5	59%	0.592	30%	0.295	S	S	*	.	H	α-helix	trans	-70.3	-28.8	178.7	-72	175	0	0	0	112.4	L457 A458 N459 P464	L457-L461 HydrophobicContact CD1-CD1 4.32Å; L457-L461 HydrophobicContact CD1-CG 4.23Å; L457-L461 HydrophobicContact CD2-CD1 4.35Å; L457-L461 HydrophobicContact CG-CD1 3.85Å; L457-L461 HydrophobicContact CG-CG 4.19Å; L457-L461 WeakPolarHBondContact O-CB 3.44Å; L457-L461 VanDerWaalsContact O-CG 3.27Å; L457-L461 WeakPolarHBondContact O-CG 3.38Å; L457-L461 PolarHBondContact O-N 3.03Å; A458-L461 PolarHBondContact O-N 3.35Å; N459-L461 VanDerWaalsContact C-N 3.34Å; N459-L461 PolarHBondContact O-N 3.41Å; L461-P464 VanDerWaalsContact O-CD 3.29Å; L461-P464 WeakPolarHBondContact O-CD 3.39Å; L461-P464 VanDerWaalsContact O-CG 3.31Å; L461-P464 WeakPolarHBondContact O-CG 3.38Å
462	Y	91.3	Very high	84	Confident	51 Å²	51	54.2 Å²	54.2	20%	0.2	29%	0.294	C	S	.	.	H	α-helix	trans	-80.5	-26.7	176.5	-152.2	-82.1	0	0	0	112.9	V293 G296 A297 T300 L364 A458 N459 L460 V465	V293-Y462 PolarHBondContact O-OH 2.71Å; G296-Y462 WeakPolarHBondContact CA-OH 3.29Å; A297-Y462 HydrophobicContact CB-CD1 4.11Å; A297-Y462 HydrophobicContact CB-CE1 3.72Å; T300-Y462 HydrophobicContact CG2-CG 4.32Å; L364-Y462 HydrophobicContact CD1-CD1 4.13Å; A458-Y462 WeakPolarHBondContact O-CB 3.36Å; A458-Y462 PolarHBondContact O-N 3.4Å; N459-Y462 PolarHBondContact O-N 3.06Å; L460-Y462 VanDerWaalsContact C-N 3.32Å; Y462-V465 HydrophobicContact CD1-CB 4.31Å; Y462-V465 HydrophobicContact CE1-CB 4.26Å; Y462-V465 HydrophobicContact CE1-CG1 4.37Å; Y462-V465 VanDerWaalsContact O-CB 3.24Å; Y462-V465 WeakPolarHBondContact O-CB 3.39Å; Y462-V465 PolarHBondContact O-N 3.01Å
463	A	88.7	Confident	82.5	Confident	14 Å²	14	56.8 Å²	56.8	12%	0.116	32%	0.321	C	S	.	.	G	3₁₀ helix	trans	-49.3	-45.9	178.2	0	0	0	0	0	115.3	L364 N459 L460 V465 L466	L364-A463 HydrophobicContact CB-CB 4.12Å; L364-A463 HydrophobicContact CD1-CB 4.48Å; N459-A463 PolarHBondContact O-N 2.82Å; N459-A463 VanDerWaalsContact O-N 3.11Å; L460-A463 WeakPolarHBondContact O-CB 3.29Å; L460-A463 PolarHBondContact O-N 3.46Å; A463-V465 VanDerWaalsContact C-N 3.26Å; A463-V465 PolarHBondContact O-N 3.18Å; A463-L466 WeakPolarHBondContact O-CB 3.43Å; A463-L466 PolarHBondContact O-N 2.89Å
464	P	88	Confident	81	Confident	73 Å²	73	59.2 Å²	59.2	47%	0.474	33%	0.334	S	S	.	.	G	3₁₀ helix	trans	-67.7	-21.7	177.1	26.2	-35.9	0	0	0	113.8	L460 L461 L466 L467	L460-P464 VanDerWaalsContact O-CD 3.25Å; L460-P464 WeakPolarHBondContact O-CD 3.23Å; L461-P464 VanDerWaalsContact O-CD 3.29Å; L461-P464 WeakPolarHBondContact O-CD 3.39Å; L461-P464 VanDerWaalsContact O-CG 3.31Å; L461-P464 WeakPolarHBondContact O-CG 3.38Å; P464-L466 PolarHBondContact O-N 3.46Å; P464-L467 HydrophobicContact CB-CD1 4.34Å; P464-L467 WeakPolarHBondContact O-CB 3.3Å; P464-L467 WeakPolarHBondContact O-CD1 3.32Å; P464-L467 VanDerWaalsContact O-CG 3.32Å; P464-L467 WeakPolarHBondContact O-CG 3.47Å; P464-L467 PolarHBondContact O-N 3.06Å
465	V	86.4	Confident	79.6	Confident	47 Å²	47	60.1 Å²	60.1	29%	0.285	33%	0.329	S	S	.	.	G	3₁₀ helix	trans	-64.7	-29.5	177.6	-174.3	0	0	0	0	110.9	V293 Y462 A463 L467 L468	V293-V465 HydrophobicContact CG1-CG1 4.03Å; V293-V465 HydrophobicContact CG2-CG1 4.16Å; Y462-V465 HydrophobicContact CD1-CB 4.31Å; Y462-V465 HydrophobicContact CE1-CB 4.26Å; Y462-V465 HydrophobicContact CE1-CG1 4.37Å; Y462-V465 VanDerWaalsContact O-CB 3.24Å; Y462-V465 WeakPolarHBondContact O-CB 3.39Å; Y462-V465 PolarHBondContact O-N 3.01Å; A463-V465 VanDerWaalsContact C-N 3.26Å; A463-V465 PolarHBondContact O-N 3.18Å; V465-L467 PolarHBondContact O-N 3.04Å; V465-L467 VanDerWaalsContact O-N 3.13Å; V465-L468 HydrophobicContact CG1-CD1 3.94Å; V465-L468 VanDerWaalsContact O-CB 3.3Å; V465-L468 WeakPolarHBondContact O-CB 3.48Å; V465-L468 WeakPolarHBondContact O-CG 3.31Å; V465-L468 PolarHBondContact O-N 2.94Å
466	L	84.5	Confident	77.5	Confident	0 Å²	0	65.5 Å²	65.5	0%	0	36%	0.363	C	S	.	.	G	3₁₀ helix	trans	-63.9	-15.2	174.2	-70	172	0	0	0	113.4	V293 A297 A361 L364 L401 A463 P464 L468 L469	V293-L466 HydrophobicContact CG1-CD2 4.35Å; A297-L466 HydrophobicContact CB-CD2 3.86Å; A361-L466 HydrophobicContact CB-CB 4.38Å; A361-L466 HydrophobicContact CB-CD1 4.01Å; A361-L466 VanDerWaalsContact N-CD1 3.28Å; L364-L466 HydrophobicContact CD1-CD1 3.49Å; L364-L466 VanDerWaalsContact CD1-CD1 3.49Å; L364-L466 HydrophobicContact CD1-CG 4.25Å; L364-L466 HydrophobicContact CG-CD1 4.4Å; L401-L466 HydrophobicContact CD1-CD2 4.37Å; L401-L466 HydrophobicContact CD2-CD2 4.06Å; A463-L466 WeakPolarHBondContact O-CB 3.43Å; A463-L466 PolarHBondContact O-N 2.89Å; P464-L466 PolarHBondContact O-N 3.46Å; L466-L468 PolarHBondContact O-N 2.87Å; L466-L469 HydrophobicContact CD2-CD1 3.55Å; L466-L469 WeakPolarHBondContact O-CB 3.42Å; L466-L469 PolarHBondContact O-N 3.42Å
467	L	82.4	Confident	75.5	Confident	92 Å²	92	72.2 Å²	72.2	48%	0.482	39%	0.388	S	S	.	.	G	3₁₀ helix	trans	-61.5	-24.4	171.2	-68.1	167	0	0	0	112.3	W357 P464 V465 L469 R470	W357-L467 HydrophobicContact CE3-CD2 4.03Å; W357-L467 HydrophobicContact CH2-CD2 3.62Å; W357-L467 HydrophobicContact CZ3-CD2 3.27Å; W357-L467 HydrophobicContact CZ3-CG 4.3Å; P464-L467 HydrophobicContact CB-CD1 4.34Å; P464-L467 WeakPolarHBondContact O-CB 3.3Å; P464-L467 WeakPolarHBondContact O-CD1 3.32Å; P464-L467 VanDerWaalsContact O-CG 3.32Å; P464-L467 WeakPolarHBondContact O-CG 3.47Å; P464-L467 PolarHBondContact O-N 3.06Å; V465-L467 PolarHBondContact O-N 3.04Å; V465-L467 VanDerWaalsContact O-N 3.13Å; L467-L469 PolarHBondContact O-N 3.34Å; L467-R470 WeakPolarHBondContact O-CB 3.36Å; L467-R470 PolarHBondContact O-N 2.84Å
468	L	78.8	Confident	73.2	Confident	106 Å²	106	70.7 Å²	70.7	56%	0.555	39%	0.386	S	S	*	.	G	3₁₀ helix	trans	-62.7	-24.4	173.2	-65.1	169.2	0	0	0	112	Y290 V293 V465 L466 R470	Y290-L468 WeakPolarHBondContact CE1-O 3.31Å; V293-L468 HydrophobicContact CG2-CD1 4.15Å; V465-L468 HydrophobicContact CG1-CD1 3.94Å; V465-L468 VanDerWaalsContact O-CB 3.3Å; V465-L468 WeakPolarHBondContact O-CB 3.48Å; V465-L468 WeakPolarHBondContact O-CG 3.31Å; V465-L468 PolarHBondContact O-N 2.94Å; L466-L468 PolarHBondContact O-N 2.87Å; L468-R470 VanDerWaalsContact C-N 3.31Å
469	L	76.9	Confident	70.7	Confident	5 Å²	5	77.3 Å²	77.3	3%	0.026	40%	0.401	C	S	.	.	G	3₁₀ helix	trans	-84.2	-2.8	176.2	-55.9	175.1	0	0	0	113.1	Y290 V293 V294 W357 L401 L466 L467 N471 V472	Y290-L469 HydrophobicContact CD1-CD2 4.07Å; V293-L469 HydrophobicContact CB-CD2 4.48Å; V293-L469 HydrophobicContact CG1-CD1 4.17Å; V293-L469 HydrophobicContact CG1-CD2 4.33Å; V293-L469 HydrophobicContact CG1-CG 4.09Å; V294-L469 HydrophobicContact CG2-CD1 3.62Å; V294-L469 HydrophobicContact CG2-CD2 3.94Å; V294-L469 HydrophobicContact CG2-CG 4.46Å; W357-L469 HydrophobicContact CB-CB 3.95Å; L401-L469 HydrophobicContact CD2-CD1 4.33Å; L466-L469 HydrophobicContact CD2-CD1 3.55Å; L466-L469 WeakPolarHBondContact O-CB 3.42Å; L466-L469 PolarHBondContact O-N 3.42Å; L467-L469 PolarHBondContact O-N 3.34Å; L469-N471 PolarHBondContact O-N 3.23Å; L469-N471 VanDerWaalsContact O-N 3.12Å; L469-V472 HydrophobicContact CB-CG2 4.07Å; L469-V472 HydrophobicContact CD2-CG2 3.98Å; L469-V472 VanDerWaalsContact O-CB 3.29Å; L469-V472 WeakPolarHBondContact O-CB 3.27Å; L469-V472 WeakPolarHBondContact O-CG2 3.27Å; L469-V472 PolarHBondContact O-N 3.25Å
470	R	74.5	Confident	68.3	Low	162 Å²	162	80 Å²	80	61%	0.611	42%	0.421	S	S	*	.	G	3₁₀ helix	trans	-55.8	-33.4	-178.4	-177.8	177.6	178.3	-175.3	0.5	113	W357 L467 L468	W357-R470 HydrophobicContact CD2-CB 4.44Å; W357-R470 HydrophobicContact CZ2-CB 4.49Å; W357-R470 HydrophobicContact CZ2-CG 4.07Å; L467-R470 WeakPolarHBondContact O-CB 3.36Å; L467-R470 PolarHBondContact O-N 2.84Å; L468-R470 VanDerWaalsContact C-N 3.31Å
471	N	65.8	Low	65.9	Low	94 Å²	94	84 Å²	84	50%	0.503	44%	0.437	S	S	.	.	G	3₁₀ helix	trans	-89.9	-0.6	-177.5	-63.2	-15.5	0	0	0	113.2	L469 G473 L474	L469-N471 PolarHBondContact O-N 3.23Å; L469-N471 VanDerWaalsContact O-N 3.12Å; N471-G473 VanDerWaalsContact C-N 3.3Å; N471-G473 PolarHBondContact O-N 3.41Å; N471-L474 WeakPolarHBondContact O-CB 3.48Å; N471-L474 PolarHBondContact O-N 3.18Å; N471-L474 VanDerWaalsContact O-N 3.12Å
472	V	64.4	Low	63.4	Low	7 Å²	7	86.1 Å²	86.1	4%	0.042	44%	0.437	C	S	.	.	G	3₁₀ helix	trans	-65.5	-34.8	-178.6	173.9	0	0	0	0	111.3	Y290 T404 F407 L469 L474 L475	Y290-V472 HydrophobicContact CD1-CG2 3.96Å; Y290-V472 HydrophobicContact CE1-CG2 4.42Å; T404-V472 HydrophobicContact CG2-CG1 4.21Å; F407-V472 HydrophobicContact CD1-CG1 3.9Å; F407-V472 HydrophobicContact CE1-CG1 3.98Å; L469-V472 HydrophobicContact CB-CG2 4.07Å; L469-V472 HydrophobicContact CD2-CG2 3.98Å; L469-V472 VanDerWaalsContact O-CB 3.29Å; L469-V472 WeakPolarHBondContact O-CB 3.27Å; L469-V472 WeakPolarHBondContact O-CG2 3.27Å; L469-V472 PolarHBondContact O-N 3.25Å; V472-L474 PolarHBondContact O-N 3.5Å; V472-L474 VanDerWaalsContact O-N 3.13Å; V472-L475 HydrophobicContact CB-CD1 4.46Å; V472-L475 HydrophobicContact CG1-CD1 4.33Å; V472-L475 HydrophobicContact CG2-CD1 4.47Å; V472-L475 WeakPolarHBondContact O-CB 3.39Å; V472-L475 PolarHBondContact O-N 2.91Å; V472-L475 VanDerWaalsContact O-N 3.09Å
473	G	53.4	Low	60.9	Low	55 Å²	55	87.3 Å²	87.3	57%	0.567	45%	0.447	S	S	*	.	G	3₁₀ helix	trans	-66.7	-9.7	175.6	0	0	0	0	0	115	N471	N471-G473 VanDerWaalsContact C-N 3.3Å; N471-G473 PolarHBondContact O-N 3.41Å
474	L	52.6	Low	58.7	Low	141 Å²	141	89.2 Å²	89.2	74%	0.738	46%	0.457	S	S	*	.	G	3₁₀ helix	trans	-96.4	-8.5	175.4	-61.9	172	0	0	0	112.7	N471 V472 T476	N471-L474 WeakPolarHBondContact O-CB 3.48Å; N471-L474 PolarHBondContact O-N 3.18Å; N471-L474 VanDerWaalsContact O-N 3.12Å; V472-L474 PolarHBondContact O-N 3.5Å; V472-L474 VanDerWaalsContact O-N 3.13Å; L474-T476 PolarHBondContact O-N 3.41Å
475	L	55.6	Low	56.7	Low	57 Å²	57	91.8 Å²	91.8	30%	0.298	47%	0.466	S	S	.	.			trans	-72.1	114.8	177	-70.4	164.2	0	0	0	109	F407 L408 V411 V472	F407-L475 HydrophobicContact CE1-CB 4.47Å; L408-L475 HydrophobicContact CD1-CD1 4.24Å; V411-L475 HydrophobicContact CG1-CB 4.24Å; V472-L475 HydrophobicContact CB-CD1 4.46Å; V472-L475 HydrophobicContact CG1-CD1 4.33Å; V472-L475 HydrophobicContact CG2-CD1 4.47Å; V472-L475 WeakPolarHBondContact O-CB 3.39Å; V472-L475 PolarHBondContact O-N 2.91Å; V472-L475 VanDerWaalsContact O-N 3.09Å
476	T	44.3	Very low	55	Low	128 Å²	128	96.1 Å²	96.1	79%	0.785	49%	0.487	S	S	*	.			trans	-66.4	139.1	171.3	12.3	0	0	0	0	110.1	L474 S478	L474-T476 PolarHBondContact O-N 3.41Å; T476-S478 PolarHBondContact O-N 3.02Å; T476-S478 VanDerWaalsContact O-N 3.09Å
477	R	45.9	Very low	53	Low	141 Å²	141	102.2 Å²	102.2	53%	0.532	52%	0.52	S	S	.	.			trans	-53.9	117.4	176.8	-155.2	175.3	-166.8	178.2	2.5	108.3	E207 R479	E207-R477 IonicContact OE1-NH2 3.04Å; E207-R477 PolarHBondContact OE1-NH2 3.23Å; R477-R479 PolarHBondContact O-N 3.49Å
478	S	41.7	Very low	51.1	Low	70 Å²	70	102.3 Å²	102.3	49%	0.49	52%	0.518	S	S	.	.			trans	-59.6	111.8	168.1	173.1	0	0	0	0	106.5	V411 T476 S480	V411-S478 WeakPolarHBondContact O-CB 3.34Å; T476-S478 PolarHBondContact O-N 3.02Å; T476-S478 VanDerWaalsContact O-N 3.09Å; S478-S480 PolarHBondContact O-N 3.3Å
479	R	37.4	Very low	49.1	Very low	183 Å²	183	102.3 Å²	102.3	69%	0.691	52%	0.524	S	S	*	.			trans	-62.3	113.7	175.3	-72.8	-176.1	178.7	-164.5	-2.9	106.4	R477 E481 V484	R477-R479 PolarHBondContact O-N 3.49Å; R479-E481 PolarHBondContact O-N 3.08Å; R479-V484 HydrophobicContact CB-CG2 4.22Å
480	S	40	Very low	47.3	Very low	59 Å²	59	108.3 Å²	108.3	41%	0.413	56%	0.563	S	S	.	*			trans	-56.7	138.8	169	-178	0	0	0	0	107.8	S478 R482 D483 V484	S478-S480 PolarHBondContact O-N 3.3Å; S480-R482 PolarHBondContact O-N 3.29Å; S480-R482 PolarHBondContact OG-N 3.43Å; S480-D483 PolarHBondContact O-N 2.95Å; S480-V484 PolarHBondContact O-N 2.72Å
481	E	39.7	Very low	45.5	Very low	166 Å²	166	108.4 Å²	108.4	78%	0.776	57%	0.571	S	S	*	*	H	α-helix	trans	-51.5	-21.2	172.2	-72.1	177.7	148.1	0	0	112.4	R479 L485	R479-E481 PolarHBondContact O-N 3.08Å; E481-L485 WeakPolarHBondContact O-CG 3.49Å; E481-L485 PolarHBondContact O-N 2.81Å; E481-L485 VanDerWaalsContact O-N 3.13Å
482	R	38.6	Very low	44.4	Very low	157 Å²	157	107 Å²	107	59%	0.592	58%	0.578	S	S	*	*	H	α-helix	trans	-70.8	-35	172.4	-67.3	-175.2	-169.9	157.3	7.8	114.5	P277 S480 V484 L485 L486	P277-R482 VanDerWaalsContact CG-NH2 3.27Å; S480-R482 PolarHBondContact O-N 3.29Å; S480-R482 PolarHBondContact OG-N 3.43Å; R482-V484 VanDerWaalsContact C-N 3.35Å; R482-L485 PolarHBondContact O-N 3.38Å; R482-L486 WeakPolarHBondContact O-CG 3.27Å; R482-L486 PolarHBondContact O-N 3.25Å
483	D	38.5	Very low	42.9	Very low	77 Å²	77	114.2 Å²	114.2	41%	0.412	62%	0.616	S	S	.	*	H	α-helix	trans	-73.8	-32.5	175.1	-75.3	-20.2	0	0	0	110.4	S480 L485 L486 D487	S480-D483 PolarHBondContact O-N 2.95Å; D483-L485 VanDerWaalsContact C-N 3.33Å; D483-L485 PolarHBondContact O-N 3.46Å; D483-L486 PolarHBondContact O-N 2.9Å; D483-D487 PolarHBondContact O-N 3.16Å
484	V	43.5	Very low	42	Very low	54 Å²	54	122.4 Å²	122.4	33%	0.327	63%	0.631	S	S	.	*	H	α-helix	trans	-63.8	-39.6	172.7	-178.1	0	0	0	0	111.1	R479 S480 R482 L486 E488	R479-V484 HydrophobicContact CB-CG2 4.22Å; S480-V484 PolarHBondContact O-N 2.72Å; R482-V484 VanDerWaalsContact C-N 3.35Å; V484-L486 VanDerWaalsContact C-N 3.27Å; V484-L486 PolarHBondContact O-N 3.24Å; V484-E488 WeakPolarHBondContact O-CB 3.45Å; V484-E488 PolarHBondContact O-N 2.98Å; V484-E488 VanDerWaalsContact O-N 3.11Å
485	L	45.1	Very low	41	Very low	126 Å²	126	121.7 Å²	121.7	66%	0.66	63%	0.628	S	S	*	*	H	α-helix	trans	-73	-12.6	177	-74.4	166.5	0	0	0	114.8	E481 R482 D483	E481-L485 WeakPolarHBondContact O-CG 3.49Å; E481-L485 PolarHBondContact O-N 2.81Å; E481-L485 VanDerWaalsContact O-N 3.13Å; R482-L485 PolarHBondContact O-N 3.38Å; D483-L485 VanDerWaalsContact C-N 3.33Å; D483-L485 PolarHBondContact O-N 3.46Å
486	L	51.8	Low	39.8	Very low	139 Å²	139	123.5 Å²	123.5	73%	0.728	65%	0.651	S	S	*	*	H	α-helix	trans	-96.6	-28.1	178	-73.5	166.8	0	0	0	112.4	R482 D483 V484	R482-L486 WeakPolarHBondContact O-CG 3.27Å; R482-L486 PolarHBondContact O-N 3.25Å; D483-L486 PolarHBondContact O-N 2.9Å; V484-L486 VanDerWaalsContact C-N 3.27Å; V484-L486 PolarHBondContact O-N 3.24Å
487	D	43.1	Very low	39.3	Very low	128 Å²	128	123.9 Å²	123.9	68%	0.684	65%	0.653	S	S	*	*	H	α-helix	trans	-89.4	-20.2	175.8	-76.2	-20.5	0	0	0	113.1	D483	D483-D487 PolarHBondContact O-N 3.16Å
488	E	41.1	Very low	38.5	Very low	94 Å²	94	128 Å²	128	44%	0.439	67%	0.668	S	S	.	*	S	Bend	trans	-84.9	124.6	168.6	-73.4	-177.3	163.9	0	0	110	V484	V484-E488 WeakPolarHBondContact O-CB 3.45Å; V484-E488 PolarHBondContact O-N 2.98Å; V484-E488 VanDerWaalsContact O-N 3.11Å
489	P	37.7	Very low	38	Very low	106 Å²	106	132.2 Å²	132.2	69%	0.688	69%	0.685	S	S	*	*			trans	-55.7	140.8	166.5	26.3	-32.8	0	0	0	107.8	Q491	P489-Q491 PolarHBondContact O-N 3.09Å
490	P	38.4	Very low	37.6	Very low	130 Å²	130	135 Å²	135	84%	0.844	70%	0.695	S	S	*	*			trans	-56.9	102.8	-165.9	21.4	-32.9	0	0	0	110.8	G492	P490-G492 PolarHBondContact O-N 3.42Å; P490-G492 VanDerWaalsContact O-N 3.15Å
491	Q	37	Very low	37.2	Very low	165 Å²	165	141.1 Å²	141.1	77%	0.771	72%	0.717	S	S	*	*			trans	-71.1	109.7	164.1	-71.4	-167.6	4.9	0	0	106	P489 L493	P489-Q491 PolarHBondContact O-N 3.09Å; Q491-L493 PolarHBondContact O-N 2.86Å; Q491-L493 VanDerWaalsContact O-N 3.12Å
492	G	42.1	Very low	36.5	Very low	64 Å²	64	144.9 Å²	144.9	66%	0.66	72%	0.724	S	S	*	*	S	Bend	trans	-51.9	114.8	-162.1	0	0	0	0	0	113.6	P490	P490-G492 PolarHBondContact O-N 3.42Å; P490-G492 VanDerWaalsContact O-N 3.15Å
493	L	34.4	Very low	36.1	Very low	159 Å²	159	143.2 Å²	143.2	83%	0.832	73%	0.734	S	S	*	*			trans	-142.8	17.7	159	-139.3	83.4	0	0	0	113	Q491	Q491-L493 PolarHBondContact O-N 2.86Å; Q491-L493 VanDerWaalsContact O-N 3.12Å
494	Y	33.5	Very low	35.8	Very low	227 Å²	227	146.3 Å²	146.3	89%	0.89	76%	0.755	S	S	*	*	S	Bend	trans	-110.5	-1.9	172.7	-79.7	-77	0	0	0	114.4
495	D	30.9	Very low	35.1	Very low	125 Å²	125	149.2 Å²	149.2	67%	0.668	78%	0.778	S	S	*	*	G	3₁₀ helix	trans	-89.3	-0.3	178.3	-89	-23.7	0	0	0	115	V497	D495-V497 PolarHBondContact O-N 3.5Å
496	A	31.9	Very low	34.4	Very low	95 Å²	95	146.4 Å²	146.4	79%	0.785	78%	0.78	S	S	*	*	G	3₁₀ helix	trans	-72.7	-11.4	178.6	0	0	0	0	0	114.2
497	V	32.8	Very low	33.3	Very low	137 Å²	137	148.4 Å²	148.4	83%	0.83	79%	0.785	S	S	*	*	G	3₁₀ helix	trans	-109	-1	-174.4	-175.7	0	0	0	0	113.3	D495	D495-V497 PolarHBondContact O-N 3.5Å
498	R	29	Very low	32.7	Very low	226 Å²	226	149.9 Å²	149.9	85%	0.853	79%	0.793	S	S	*	*	S	Bend	trans	-118.1	4.3	-179.9	-93.1	-165.5	179	-169.7	2.2	118.2
499	L	31.3	Very low	32.1	Very low	159 Å²	159	149.3 Å²	149.3	83%	0.832	81%	0.812	S	S	*	*			trans	-126.2	38.5	179.1	-87.8	160.4	0	0	0	114.4
500	R	29	Very low	31.5	Very low	241 Å²	241	153.1 Å²	153.1	91%	0.909	82%	0.821	S	S	*	*			trans	-117	63.9	163.9	-128.8	-171.5	-169.9	-179.4	3.2	110.7
501	E	31.2	Very low	31.7	Very low	188 Å²	188	151.5 Å²	151.5	88%	0.879	81%	0.811	S	S	*	*			trans	-170.4	91.7	157.6	-108.3	168.8	-148.3	0	0	110.6
502	R	26.4	Very low	31.2	Very low	246 Å²	246	155.5 Å²	155.5	93%	0.928	82%	0.818	S	S	*	*			trans	-171.9	143.6	131.5	-101.6	170.3	-175.4	-166.2	1.2	110.7
503	P	29.3	Very low	30.4	Very low	121 Å²	121	157.8 Å²	157.8	79%	0.786	82%	0.824	S	S	*	*			trans	-86.4	162.2	-164	35.4	-34.4	0	0	0	113.6
504	V	33	Very low	30.7	Very low	143 Å²	143	155.8 Å²	155.8	87%	0.867	82%	0.821	S	S	*	*			trans	-51.4	134.4	174.7	175.8	0	0	0	0	113.3
505	S	29.2	Very low	30.7	Very low	115 Å²	115	150.5 Å²	150.5	80%	0.804	81%	0.814	S	S	*	*			trans	-152.2	106.8	145.9	67.6	0	0	0	0	112.1
506	G	29.4	Very low	30.6	Very low	67 Å²	67	147.5 Å²	147.5	69%	0.691	81%	0.813	S	S	*	*				74.3	118.4	129.7	0	0	0	0	0	122
507	Q	28.8	Very low	30.7	Very low	180 Å²	180	148.3 Å²	148.3	84%	0.841	81%	0.811	S	S	*	*			trans	93.5	105.4	138.6	-68.2	-179.7	-13	0	0	121
508	D	30.9	Very low	30.4	Very low	160 Å²	160	150.5 Å²	150.5	86%	0.856	81%	0.809	S	S	*	*				57.6	121.5	124	-55.4	-26	0	0	0	122
509	G	28.4	Very low	30.2	Very low	82 Å²	82	146.7 Å²	146.7	85%	0.845	81%	0.806	S	S	*	*			trans	139.8	91.7	147.5	0	0	0	0	0	116.5
510	E	25.1	Very low	29.9	Very low	185 Å²	185	147.7 Å²	147.7	86%	0.864	81%	0.806	S	S	*	*			trans	-81.3	174	149.3	-109.1	-154.2	179.6	0	0	109.8
511	P	42.4	Very low	29.8	Very low	97 Å²	97	142.3 Å²	142.3	63%	0.63	80%	0.804	S	S	*	*			cis	-135.7	177.8	-14	28.2	-6.3	0	0	0	113
512	R	25.7	Very low	29.6	Very low	248 Å²	248	142.3 Å²	142.3	94%	0.936	80%	0.804	S	S	*	*			trans	179	121.5	140.5	-98.9	160.5	-169.1	-165.9	4.1	113.8
513	S	26.5	Very low	29.6	Very low	112 Å²	112	137.8 Å²	137.8	78%	0.783	80%	0.798	S	S	*	*			trans	-103.6	177.7	146.8	45.3	0	0	0	0	108.1
514	P	39.8	Very low	29.5	Very low	117 Å²	117	140 Å²	140	76%	0.76	80%	0.804	S	S	*	*			cis	-131.2	-147.2	-5.8	42.2	-21.4	0	0	0	110.1
515	P	33.7	Very low	29.2	Very low	116 Å²	116	143 Å²	143	75%	0.753	80%	0.801	S	S	*	*			cis	-129.7	174.6	-17.4	35.7	-15.2	0	0	0	114.9
516	G	28.8	Very low	29.1	Very low	63 Å²	63	143.9 Å²	143.9	65%	0.649	80%	0.797	S	S	*	*			trans	-66.5	172.2	163.3	0	0	0	0	0	112.5
517	P	34.3	Very low	29	Very low	112 Å²	112	150.6 Å²	150.6	73%	0.727	80%	0.802	S	S	*	*				-156.3	176.2	80.3	34.9	-11.2	0	0	0	117
518	F	26.1	Very low	29	Very low	182 Å²	182	151.3 Å²	151.3	80%	0.798	80%	0.799	S	S	*	*			trans	77.2	111.4	162.4	-68.8	-77.3	0	0	0	121
519	D	26.1	Very low	28.8	Very low	146 Å²	146	154.5 Å²	154.5	78%	0.781	80%	0.8	S	S	*	*				43.1	148.3	116.7	-85.2	-33	0	0	0	121.9
520	E	24.7	Very low	28.8	Very low	181 Å²	181	156.3 Å²	156.3	85%	0.846	80%	0.795	S	S	*	*			trans	93.3	92.1	164.8	-57.7	-175	163.5	0	0	117.3
521	C	27.3	Very low	29	Very low	128 Å²	128	159.3 Å²	159.3	87%	0.865	80%	0.799	S	S	*	*				172.7	91.7	109.4	-84.5	0	0	0	0	109.6
522	E	26.3	Very low	28.5	Very low	187 Å²	187	163.7 Å²	163.7	87%	0.874	83%	0.832	S	S	*	*			trans	-70.8	126.2	144.8	-83.3	-177.6	131.3	0	0	107.4
523	D	26.4	Very low	28.7	Very low	151 Å²	151	159.5 Å²	159.5	81%	0.807	83%	0.826	S	S	*	*			trans	153.6	101.6	144.6	-83.4	-24.1	0	0	0	109.7
524	D	26.9	Very low	28.8	Very low	169 Å²	169	161.9 Å²	161.9	90%	0.904	83%	0.829	S	S	*	*				-163.2	96.8	126.9	-117.7	-16.8	0	0	0	110.2
525	Y	27.8	Very low	28.2	Very low	204 Å²	204	164.4 Å²	164.4	80%	0.8	83%	0.833	S	S	*	*			trans	-83.4	140.7	169.2	-112.4	-87.8	0	0	0	109.7
526	N	25.6	Very low	27.8	Very low	134 Å²	134	167.3 Å²	167.3	72%	0.717	84%	0.837	S	S	*	*			trans	55.4	107	149.1	-89.2	-21.6	0	0	0	118.1
527	Y	28	Very low	27.8	Very low	208 Å²	208	173.8 Å²	173.8	82%	0.816	85%	0.849	S	S	*	*			trans	-156	133.1	138.4	-114.4	-77.3	0	0	0	113.1
528	Y	27.9	Very low	27.4	Very low	196 Å²	196	177.9 Å²	177.9	77%	0.769	86%	0.857	S	S	*	*			trans	93.6	72.2	165.7	-64.3	-75.1	0	0	0	120.2
529	Y	27.4	Very low	27.4	Very low	226 Å²	226	177.6 Å²	177.6	89%	0.886	86%	0.861	S	S	*	*				-98.7	148.8	128.7	-114.1	-90	0	0	0	108.9
530	T	28.7	Very low	27.5	Very low	120 Å²	120	180.1 Å²	180.1	74%	0.736	87%	0.867	S	S	*	*			trans	95.4	107	168.1	69.7	0	0	0	0	119.8
531	R	28.5	Very low	27.8	Very low	248 Å²	248	180 Å²	180	94%	0.936	87%	0.869	S	S	*	*			trans	168.1	127.1	133.4	-92.3	174.8	-178	-172.1	2	105.4
532	S	32.6	Very low	27.8	Very low	189 Å²	189	184.7 Å²	184.7	100%	1.322	87%	0.87	S	S	*	*			cis	-172.4	0	25.7	42.3	0	0	0	0	108.8

Retrieved 532 of 532 residues in 921 ms (Link to these results)

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