A0A096N7W7_PAPAN Loading...

Vang-like protein

AlphaFold DB , UniProt , Accession A0A096N7W7, Species PAPAN (Papio anubis, Olive baboon), Gene VANGL1, Length 524 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.4	Very low	30.5	Very low	232 Å²	232	145.5 Å²	145.5	100%	1.143	79%	0.788	S	S	*	*				0	89.3	0	-81.4	174.6	163.4	0	0	106.8
2	D	28.5	Very low	30.1	Very low	143 Å²	143	150.6 Å²	150.6	77%	0.765	79%	0.79	S	S	*	*			trans	49.5	100.2	133.4	-44.2	-26.8	0	0	0	116.6
3	T	34	Very low	30	Very low	124 Å²	124	156.8 Å²	156.8	76%	0.761	80%	0.799	S	S	*	*				70	128.9	78.5	60.9	0	0	0	0	115.4
4	E	34.2	Very low	29.8	Very low	186 Å²	186	151.7 Å²	151.7	87%	0.869	79%	0.785	S	S	*	*			trans	133.1	144.6	148	-79.7	-173	165	0	0	110.3
5	S	32.6	Very low	29.6	Very low	94 Å²	94	149.5 Å²	149.5	66%	0.657	79%	0.788	S	S	*	*			cis	-174.7	171.8	-10	51.8	0	0	0	0	104.8
6	T	31.5	Very low	29.4	Very low	129 Å²	129	151.6 Å²	151.6	79%	0.791	79%	0.792	S	S	*	*				156	91.8	129.7	-47	0	0	0	0	111.5
7	Y	27.7	Very low	29.2	Very low	208 Å²	208	147.6 Å²	147.6	82%	0.816	78%	0.78	S	S	*	*				11	133.2	129.7	-144.5	-104.2	0	0	0	119.7
8	S	31.2	Very low	29.1	Very low	117 Å²	117	150.1 Å²	150.1	82%	0.818	78%	0.783	S	S	*	*				-164.9	114.4	120.3	45	0	0	0	0	111.1
9	G	25.2	Very low	29	Very low	58 Å²	58	152.2 Å²	152.2	60%	0.598	79%	0.785	S	S	*	*			trans	-81.5	155.5	161.7	0	0	0	0	0	110.8
10	Y	27.6	Very low	29	Very low	232 Å²	232	150.7 Å²	150.7	91%	0.91	79%	0.788	S	S	*	*			trans	-136.5	146.3	153.3	-142.1	-95.1	0	0	0	110.5
11	S	28.6	Very low	28.9	Very low	78 Å²	78	150.9 Å²	150.9	55%	0.545	79%	0.785	S	S	.	*			trans	-93	152.2	-152.2	46.9	0	0	0	0	115.2
12	Y	26	Very low	28.7	Very low	206 Å²	206	151.7 Å²	151.7	81%	0.808	78%	0.775	S	S	*	*			trans	30.8	129.4	134.2	-79.1	-99.9	0	0	0	120.4
13	Y	28.1	Very low	28.7	Very low	231 Å²	231	153.3 Å²	153.3	91%	0.906	78%	0.778	S	S	*	*				-153.3	136.5	113.8	-122.8	-87.7	0	0	0	111.9
14	S	27.7	Very low	28.4	Very low	86 Å²	86	151.1 Å²	151.1	60%	0.601	78%	0.78	S	S	*	*			trans	-96.8	153.8	-178.7	48.5	0	0	0	0	111.3
15	S	26.5	Very low	28.2	Very low	118 Å²	118	150.7 Å²	150.7	83%	0.825	78%	0.778	S	S	*	*			trans	-170.1	100	149.3	30.6	0	0	0	0	109.5
16	H	26.6	Very low	28.1	Very low	184 Å²	184	158 Å²	158	85%	0.852	79%	0.791	S	S	*	*				67.6	103.9	92.2	-112.3	-38	0	0	0	116.6
17	S	26.4	Very low	28.1	Very low	84 Å²	84	158.2 Å²	158.2	59%	0.587	79%	0.792	S	S	*	*				103.3	132.6	114.3	100.3	0	0	0	0	121
18	K	27.7	Very low	28.4	Very low	192 Å²	192	158.9 Å²	158.9	84%	0.835	79%	0.794	S	S	*	*			trans	91.8	95.8	138.8	-73.8	173.2	-179.4	178.6	0	120.4
19	K	27.3	Very low	28.4	Very low	190 Å²	190	161.6 Å²	161.6	83%	0.826	79%	0.793	S	S	*	*				30.7	126.4	114.3	-87.3	-178.5	172.3	178.8	0	117.9
20	S	28.1	Very low	28.7	Very low	122 Å²	122	170 Å²	170	85%	0.853	81%	0.807	S	S	*	*				-151.5	137.4	121.7	67.4	0	0	0	0	113.3
21	H	27.5	Very low	28.9	Very low	155 Å²	155	168 Å²	168	72%	0.718	81%	0.805	S	S	*	*			trans	-64.9	149.1	174	-91.1	-95	0	0	0	112.9
22	R	29.2	Very low	29	Very low	249 Å²	249	173.3 Å²	173.3	94%	0.94	82%	0.819	S	S	*	*				-169.9	142.3	107.7	-106.4	176.2	176	177.1	-0.8	115
23	Q	29.3	Very low	29.1	Very low	177 Å²	177	168.3 Å²	168.3	83%	0.827	81%	0.814	S	S	*	*			trans	-74.2	155.5	-178.7	-129.2	166.7	-15.7	0	0	111.9
24	G	27.7	Very low	30	Very low	77 Å²	77	162.9 Å²	162.9	79%	0.794	81%	0.807	S	S	*	*			trans	-174.2	75.4	167.1	0	0	0	0	0	112.3
25	E	30.8	Very low	30.1	Very low	178 Å²	178	170.9 Å²	170.9	83%	0.832	82%	0.824	S	S	*	*			trans	-62.8	140.6	161.5	-77.8	177.9	131.6	0	0	110.5
26	R	30.4	Very low	30.2	Very low	247 Å²	247	172.7 Å²	172.7	93%	0.932	82%	0.824	S	S	*	*			trans	-168.6	122.8	133.2	-103.8	164.6	-169.7	-168.4	3.4	112.1
27	T	31.2	Very low	30.5	Very low	133 Å²	133	173.6 Å²	173.6	82%	0.816	83%	0.826	S	S	*	*			trans	-64.2	139.5	164	28.1	0	0	0	0	112.2
28	R	32.4	Very low	30.7	Very low	223 Å²	223	177.1 Å²	177.1	84%	0.842	84%	0.838	S	S	*	*				169.4	128.2	121.5	-100	179.8	162.9	143.4	-2.7	113.9
29	E	31.5	Very low	30.8	Very low	173 Å²	173	171.8 Å²	171.8	81%	0.808	84%	0.837	S	S	*	*			trans	56	131.8	131.7	-68.2	-178.6	163	0	0	124.1
30	R	32.1	Very low	31	Very low	234 Å²	234	175 Å²	175	88%	0.883	84%	0.844	S	S	*	*			trans	-59.3	145.2	162.6	-71.8	168.1	161.7	-176.6	-5.6	111.7
31	H	32.3	Very low	31.1	Very low	190 Å²	190	173 Å²	173	88%	0.88	84%	0.842	S	S	*	*				-163.3	162.4	127.3	-96.8	-65	0	0	0	111.8
32	K	30.2	Very low	31.3	Very low	191 Å²	191	170.8 Å²	170.8	83%	0.83	84%	0.844	S	S	*	*			trans	-68.2	148	-160	-80.7	169.5	168.1	176.2	0	117.6
33	S	29.1	Very low	31.3	Very low	101 Å²	101	167.9 Å²	167.9	71%	0.706	84%	0.841	S	S	*	*			trans	-6.2	177.6	143	70.1	0	0	0	0	121.8
34	P	46.2	Very low	31.5	Very low	117 Å²	117	168.5 Å²	168.5	76%	0.76	84%	0.841	S	S	*	*			cis	-135.8	174.4	-23.6	26	-3.7	0	0	0	113.6
35	R	29.4	Very low	31.6	Very low	254 Å²	254	170.3 Å²	170.3	96%	0.958	84%	0.842	S	S	*	*			trans	-156.7	128.7	149.5	-140.6	169.9	174.1	175.5	-2.5	113.7
36	N	30	Very low	31.4	Very low	155 Å²	155	167.4 Å²	167.4	83%	0.829	84%	0.836	S	S	*	*			trans	-58.5	150.3	173.3	-80.9	-20.3	0	0	0	113.5
37	K	32.3	Very low	31.1	Very low	203 Å²	203	161.8 Å²	161.8	88%	0.883	83%	0.829	S	S	*	*			trans	-157.7	131.7	133.6	-148.6	168.4	-179.3	178.3	0	112
38	D	30.5	Very low	31	Very low	159 Å²	159	162.5 Å²	162.5	85%	0.85	83%	0.827	S	S	*	*			trans	-65.7	155.6	178.4	-58.1	-71.4	0	0	0	114
39	G	30.4	Very low	30.9	Very low	79 Å²	79	160.1 Å²	160.1	81%	0.814	83%	0.825	S	S	*	*			trans	-167.6	95.5	168.9	0	0	0	0	0	111.8
40	R	31.7	Very low	30.7	Very low	259 Å²	259	157.5 Å²	157.5	98%	0.977	82%	0.823	S	S	*	*			trans	-68.4	148.5	172.8	-83.2	177	166.6	-159.7	-2.7	112.1
41	G	29	Very low	30.7	Very low	78 Å²	78	152.3 Å²	152.3	80%	0.804	82%	0.82	S	S	*	*			trans	99.8	113.9	136.4	0	0	0	0	0	117.3
42	S	31.1	Very low	30.5	Very low	109 Å²	109	150.3 Å²	150.3	76%	0.762	82%	0.821	S	S	*	*				178.6	109.5	117.5	-172.6	0	0	0	0	109.3
43	E	30.9	Very low	30.5	Very low	189 Å²	189	144.7 Å²	144.7	88%	0.883	82%	0.817	S	S	*	*			trans	-66.9	130.5	161.8	-63.2	166.6	158.1	0	0	108.7
44	K	32.8	Very low	30.5	Very low	190 Å²	190	148.9 Å²	148.9	83%	0.826	83%	0.826	S	S	*	*			trans	-145	97.3	154.6	-86.5	-169.5	177.5	176.5	0	108.6
45	S	28.6	Very low	30.2	Very low	114 Å²	114	148.5 Å²	148.5	80%	0.797	82%	0.823	S	S	*	*			trans	-68.4	129.6	159.2	42.5	0	0	0	0	108.9
46	V	26.8	Very low	30.3	Very low	118 Å²	118	144.9 Å²	144.9	72%	0.715	82%	0.822	S	S	*	*			trans	-127.8	105.1	165.7	179.2	0	0	0	0	106.8	I48	V46-I48 HydrophobicContact CG1-CD1 4.38Å; V46-I48 HydrophobicContact CG1-CG1 3.98Å
47	T	25.1	Very low	30.4	Very low	128 Å²	128	145.7 Å²	145.7	79%	0.785	83%	0.825	S	S	*	*			trans	-79.5	124.6	169.3	-47.7	0	0	0	0	107.5
48	I	28.9	Very low	30.2	Very low	149 Å²	149	139.6 Å²	139.6	76%	0.764	82%	0.82	S	S	*	*			trans	-117.6	108	169.1	-57.8	179	0	0	0	107.2	V46	V46-I48 HydrophobicContact CG1-CD1 4.38Å; V46-I48 HydrophobicContact CG1-CG1 3.98Å
49	Q	29.6	Very low	30.1	Very low	172 Å²	172	139.4 Å²	139.4	80%	0.804	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-81.2	138.4	161	-92.5	172.9	-9.1	0	0	108.8
50	P	28.3	Very low	29.9	Very low	118 Å²	118	143.4 Å²	143.4	77%	0.766	82%	0.822	S	S	*	*	P	Polyproline II helix	trans	-88.3	149.1	177.8	35.2	-31.5	0	0	0	111.1
51	P	31.5	Very low	29.7	Very low	126 Å²	126	136.4 Å²	136.4	82%	0.818	81%	0.812	S	S	*	*	P	Polyproline II helix	trans	-103.9	137.6	157.8	32.4	-23	0	0	0	112.1
52	T	29.3	Very low	29.8	Very low	147 Å²	147	137.4 Å²	137.4	90%	0.902	81%	0.813	S	S	*	*	P	Polyproline II helix	trans	-74.7	150.7	168.3	36.7	0	0	0	0	113
53	G	29	Very low	29.7	Very low	73 Å²	73	142.7 Å²	142.7	75%	0.753	82%	0.816	S	S	*	*			trans	112.8	99.1	142.9	0	0	0	0	0	118.2
54	E	30.2	Very low	29.7	Very low	190 Å²	190	140.5 Å²	140.5	89%	0.888	82%	0.816	S	S	*	*			trans	-4.3	177.9	147.3	-58.7	-174.1	159.6	0	0	121.9
55	P	39.7	Very low	29.7	Very low	108 Å²	108	138.7 Å²	138.7	70%	0.701	81%	0.811	S	S	*	*				-130.1	169.5	-51.4	35.9	-20.5	0	0	0	110.6
56	L	30.6	Very low	29.9	Very low	178 Å²	178	142.4 Å²	142.4	93%	0.932	82%	0.816	S	S	*	*			trans	-166.9	132.4	153.1	-106.6	167	0	0	0	112.2
57	L	31.4	Very low	30.6	Very low	172 Å²	172	143.9 Å²	143.9	90%	0.901	82%	0.824	S	S	*	*			trans	-65.2	150.3	-179.1	-82.5	144.3	0	0	0	114.1
58	G	28.2	Very low	31.5	Very low	75 Å²	75	145.7 Å²	145.7	77%	0.773	82%	0.824	S	S	*	*			trans	-169.4	101.2	162.7	0	0	0	0	0	111.2
59	N	28.3	Very low	32.1	Very low	155 Å²	155	145.5 Å²	145.5	83%	0.829	83%	0.825	S	S	*	*			trans	-52.3	142.4	171.8	-100.8	-0.7	0	0	0	112
60	D	27.2	Very low	32.7	Very low	164 Å²	164	144.1 Å²	144.1	88%	0.877	82%	0.823	S	S	*	*				-162.1	145.8	123.9	-100.6	-23	0	0	0	113.1
61	S	27.7	Very low	33.6	Very low	111 Å²	111	143.8 Å²	143.8	78%	0.776	81%	0.814	S	S	*	*			trans	-72.7	140.8	-162.4	53	0	0	0	0	116.9
62	A	30.7	Very low	34.5	Very low	100 Å²	100	149.3 Å²	149.3	83%	0.826	82%	0.819	S	S	*	*			trans	-155.1	108.3	141.9	0	0	0	0	0	110.8
63	R	28.4	Very low	35.7	Very low	219 Å²	219	145 Å²	145	83%	0.826	80%	0.804	S	S	*	*			trans	-58.8	132.5	169.9	-85.1	167.3	145.7	152.2	-7.2	111.3
64	T	32.2	Very low	36.4	Very low	144 Å²	144	149.5 Å²	149.5	88%	0.883	81%	0.806	S	S	*	*			trans	-137.4	111.6	141.9	-16.3	0	0	0	0	106.4
65	E	32.1	Very low	37	Very low	152 Å²	152	146.8 Å²	146.8	71%	0.71	80%	0.802	S	S	*	*			trans	-74.1	119	179.2	-71.8	171.1	169.1	0	0	109.3
66	E	33.8	Very low	37.3	Very low	192 Å²	192	147.9 Å²	147.9	90%	0.897	81%	0.807	S	S	*	*			trans	-115.1	118.5	150.5	-73.9	-169.4	172	0	0	106.9	Q68	E66-Q68 PolarHBondContact O-N 2.61Å; E66-Q68 VanDerWaalsContact O-N 3.15Å
67	V	41.3	Very low	38.2	Very low	148 Å²	148	145.2 Å²	145.2	90%	0.897	80%	0.799	S	S	*	*			trans	-66.6	105.7	-175.7	174.7	0	0	0	0	108.8
68	Q	42.8	Very low	38.4	Very low	166 Å²	166	141.1 Å²	141.1	78%	0.776	79%	0.79	S	S	*	*			trans	-115.1	123.9	168.9	-167.2	156.1	-6.8	0	0	108.3	E66 D70	E66-Q68 PolarHBondContact O-N 2.61Å; E66-Q68 VanDerWaalsContact O-N 3.15Å; Q68-D70 PolarHBondContact O-N 3.16Å
69	D	42.3	Very low	38.9	Very low	146 Å²	146	145.9 Å²	145.9	78%	0.781	80%	0.795	S	S	*	*			trans	-74	88.6	-168	-149	7.1	0	0	0	110.4	N71	D69-N71 VanDerWaalsContact C-N 3.35Å; D69-N71 PolarHBondContact O-N 3.34Å
70	D	42.5	Very low	39.5	Very low	143 Å²	143	144.6 Å²	144.6	77%	0.765	79%	0.793	S	S	*	*			trans	-92.2	61.6	178.7	-79.3	-29.1	0	0	0	111.6	Q68	Q68-D70 PolarHBondContact O-N 3.16Å
71	N	46.1	Very low	40.3	Very low	110 Å²	110	139.5 Å²	139.5	59%	0.588	78%	0.78	S	S	*	*			trans	-101	69.1	167.3	-168.8	13.1	0	0	0	111	D69	D69-N71 VanDerWaalsContact C-N 3.35Å; D69-N71 PolarHBondContact O-N 3.34Å
72	W	50.4	Low	40.8	Very low	242 Å²	242	140.4 Å²	140.4	92%	0.917	78%	0.78	S	S	*	*			trans	-109.1	22.3	179.1	-87.7	91.3	0	0	0	114
73	G	55	Low	41	Very low	58 Å²	58	140.9 Å²	140.9	60%	0.598	78%	0.778	S	S	*	*	S	Bend	trans	-140.8	-9.7	-169.6	0	0	0	0	0	119.2
74	E	42.8	Very low	41.6	Very low	166 Å²	166	138.6 Å²	138.6	78%	0.776	78%	0.777	S	S	*	*			trans	-100.8	10.7	-165.7	-68.7	-166.8	163.1	0	0	116.7	T76	E74-T76 VanDerWaalsContact C-N 3.29Å; E74-T76 PolarHBondContact O-N 3.17Å
75	T	44.3	Very low	41.9	Very low	133 Å²	133	141.1 Å²	141.1	82%	0.816	78%	0.778	S	S	*	*			trans	-92.5	64.8	166.3	46.3	0	0	0	0	111.3	T77	T75-T77 PolarHBondContact O-N 2.88Å
76	T	45.9	Very low	42.2	Very low	132 Å²	132	137.9 Å²	137.9	81%	0.81	77%	0.772	S	S	*	*			trans	-76.1	77.7	164.7	-49	0	0	0	0	108.7	E74	E74-T76 VanDerWaalsContact C-N 3.29Å; E74-T76 PolarHBondContact O-N 3.17Å
77	T	48.3	Very low	42.7	Very low	122 Å²	122	135.7 Å²	135.7	75%	0.748	77%	0.765	S	S	*	*			trans	-88.7	116.6	164.5	47.2	0	0	0	0	109	T75 I79	T75-T77 PolarHBondContact O-N 2.88Å; T77-I79 PolarHBondContact O-N 2.81Å
78	A	36.8	Very low	42.9	Very low	86 Å²	86	130 Å²	130	71%	0.711	73%	0.732	S	S	*	*			trans	-38.8	125.8	177.3	0	0	0	0	0	113.5	T80	A78-T80 VanDerWaalsContact C-N 3.35Å; A78-T80 PolarHBondContact O-N 3.16Å; A78-T80 VanDerWaalsContact O-N 3.08Å
79	I	38.6	Very low	43.2	Very low	175 Å²	175	130.3 Å²	130.3	90%	0.897	73%	0.733	S	S	*	*			trans	-75.2	93.8	163.4	-62.5	170.7	0	0	0	106.3	T77	T77-I79 PolarHBondContact O-N 2.81Å
80	T	39.8	Very low	43.8	Very low	128 Å²	128	128.5 Å²	128.5	79%	0.785	72%	0.72	S	S	*	*			trans	-70.5	136.9	161.8	31.3	0	0	0	0	109.1	A78	A78-T80 VanDerWaalsContact C-N 3.35Å; A78-T80 PolarHBondContact O-N 3.16Å; A78-T80 VanDerWaalsContact O-N 3.08Å
81	G	45.4	Very low	44.4	Very low	57 Å²	57	125.3 Å²	125.3	59%	0.588	70%	0.703	S	S	*	*			trans	-69.6	168.5	-172.6	0	0	0	0	0	115.5
82	T	38.4	Very low	44.9	Very low	129 Å²	129	125 Å²	125	79%	0.791	70%	0.7	S	S	*	*			trans	70.7	105.5	148.2	65.2	0	0	0	0	118.6
83	S	34.7	Very low	45.2	Very low	110 Å²	110	115.6 Å²	115.6	77%	0.769	67%	0.674	S	S	*	*				-134.1	88.3	129.2	56.5	0	0	0	0	109.5	H85	S83-H85 PolarHBondContact O-N 3.24Å
84	E	40.9	Very low	45.3	Very low	172 Å²	172	119 Å²	119	80%	0.804	67%	0.669	S	S	*	*			trans	-70.6	80.7	163.1	-61.7	-175.6	169.9	0	0	108.1
85	H	37.8	Very low	46	Very low	196 Å²	196	116.3 Å²	116.3	91%	0.907	66%	0.659	S	S	*	*			trans	178.5	48.6	157.4	-91.8	-33	0	0	0	112.6	S83	S83-H85 PolarHBondContact O-N 3.24Å
86	S	37.3	Very low	46.6	Very low	84 Å²	84	111.8 Å²	111.8	59%	0.587	63%	0.633	S	S	*	*			trans	-114.2	112.3	154.7	62	0	0	0	0	107.5	S88	S86-S88 PolarHBondContact O-N 2.89Å
87	I	45.7	Very low	47.1	Very low	146 Å²	146	111.6 Å²	111.6	75%	0.749	62%	0.621	S	S	*	*			trans	-60.9	92.5	162.6	-65.5	171.7	0	0	0	105.3	I92	I87-I92 HydrophobicContact CG2-CG1 4.44Å
88	S	45.3	Very low	47.4	Very low	29 Å²	29	111 Å²	111	20%	0.203	61%	0.612	C	S	.	*			trans	-81	157.4	178.1	63.5	0	0	0	0	108	S86 E90 D91	S86-S88 PolarHBondContact O-N 2.89Å; S88-E90 WeakPolarHBondContact CB-OE2 3.34Å; S88-E90 PolarHBondContact O-N 3.46Å; S88-E90 VanDerWaalsContact OG-CB 3.28Å; S88-E90 WeakPolarHBondContact OG-CB 3.39Å; S88-E90 VanDerWaalsContact OG-CD 3.29Å; S88-E90 VanDerWaalsContact OG-CG 3.32Å; S88-E90 WeakPolarHBondContact OG-CG 3.34Å; S88-E90 PolarHBondContact OG-OE2 2.9Å; S88-D91 PolarHBondContact O-N 3.07Å; S88-D91 VanDerWaalsContact O-N 3.11Å
89	Q	49.6	Very low	48.2	Very low	173 Å²	173	111.6 Å²	111.6	81%	0.808	60%	0.602	S	S	*	*	H	α-helix	trans	-51.1	-15.6	172.6	-93.7	-178.4	-27.5	0	0	113.7	A93	Q89-A93 WeakPolarHBondContact O-CB 3.32Å; Q89-A93 PolarHBondContact O-N 3.39Å
90	E	53.9	Low	48.8	Very low	108 Å²	108	107 Å²	107	51%	0.505	58%	0.577	S	S	.	*	H	α-helix	trans	-68.6	-39.3	179.9	-48.5	167.3	141.2	0	0	112.4	S88 R94	S88-E90 WeakPolarHBondContact CB-OE2 3.34Å; S88-E90 PolarHBondContact O-N 3.46Å; S88-E90 VanDerWaalsContact OG-CB 3.28Å; S88-E90 WeakPolarHBondContact OG-CB 3.39Å; S88-E90 VanDerWaalsContact OG-CD 3.29Å; S88-E90 VanDerWaalsContact OG-CG 3.32Å; S88-E90 WeakPolarHBondContact OG-CG 3.34Å; S88-E90 PolarHBondContact OG-OE2 2.9Å; E90-R94 WeakPolarHBondContact O-CG 3.26Å; E90-R94 PolarHBondContact O-N 2.97Å; E90-R94 VanDerWaalsContact O-N 3.15Å
91	D	54.8	Low	49.5	Very low	75 Å²	75	107.1 Å²	107.1	40%	0.401	57%	0.573	S	S	.	*	H	α-helix	trans	-75.5	-34.7	175.9	-74	-22.1	0	0	0	111.1	S88 R94 I95	S88-D91 PolarHBondContact O-N 3.07Å; S88-D91 VanDerWaalsContact O-N 3.11Å; D91-R94 PolarHBondContact O-N 2.82Å; D91-I95 VanDerWaalsContact O-CB 3.29Å; D91-I95 WeakPolarHBondContact O-CB 3.44Å; D91-I95 WeakPolarHBondContact O-CD1 3.43Å; D91-I95 WeakPolarHBondContact O-CG1 3.07Å; D91-I95 PolarHBondContact O-N 2.91Å
92	I	58.1	Low	50	Low	104 Å²	104	108.8 Å²	108.8	53%	0.533	58%	0.575	S	S	.	*	H	α-helix	trans	-66.8	-39.4	176	-58.7	174.2	0	0	0	110.7	I87 S96	I87-I92 HydrophobicContact CG2-CG1 4.44Å; I92-S96 VanDerWaalsContact O-CB 3.23Å; I92-S96 WeakPolarHBondContact O-CB 3.19Å; I92-S96 PolarHBondContact O-N 3.41Å
93	A	56.2	Low	50.6	Low	45 Å²	45	105.6 Å²	105.6	37%	0.372	56%	0.555	S	S	.	*	H	α-helix	trans	-69.4	-39.1	177.5	0	0	0	0	0	112.4	Q89 S96 K97	Q89-A93 WeakPolarHBondContact O-CB 3.32Å; Q89-A93 PolarHBondContact O-N 3.39Å; A93-S96 PolarHBondContact O-N 3.31Å; A93-K97 WeakPolarHBondContact O-CB 3.06Å; A93-K97 PolarHBondContact O-N 3.45Å
94	R	57.7	Low	51.1	Low	130 Å²	130	102.9 Å²	102.9	49%	0.491	55%	0.545	S	S	.	.	H	α-helix	trans	-68.5	-45.3	174.1	-76.1	177.4	179.5	168.4	-5	112.4	E90 D91 S96 K97 D98	E90-R94 WeakPolarHBondContact O-CG 3.26Å; E90-R94 PolarHBondContact O-N 2.97Å; E90-R94 VanDerWaalsContact O-N 3.15Å; D91-R94 PolarHBondContact O-N 2.82Å; R94-S96 VanDerWaalsContact C-N 3.27Å; R94-S96 PolarHBondContact O-N 3.45Å; R94-K97 PolarHBondContact O-N 3.05Å; R94-K97 VanDerWaalsContact O-N 3.16Å; R94-D98 WeakPolarHBondContact O-CB 3.43Å; R94-D98 PolarHBondContact O-N 2.94Å
95	I	57	Low	51.6	Low	108 Å²	108	101.4 Å²	101.4	55%	0.554	54%	0.542	S	S	*	.	H	α-helix	trans	-61.2	-38.5	174	-67.4	164.3	0	0	0	110.5	D91 M99	D91-I95 VanDerWaalsContact O-CB 3.29Å; D91-I95 WeakPolarHBondContact O-CB 3.44Å; D91-I95 WeakPolarHBondContact O-CD1 3.43Å; D91-I95 WeakPolarHBondContact O-CG1 3.07Å; D91-I95 PolarHBondContact O-N 2.91Å; I95-M99 WeakPolarHBondContact O-CB 3.31Å; I95-M99 PolarHBondContact O-N 3.43Å
96	S	56.3	Low	52.4	Low	39 Å²	39	97.1 Å²	97.1	27%	0.273	53%	0.526	S	S	.	.	H	α-helix	trans	-65.7	-40.2	175.4	-173.2	0	0	0	0	112.3	I92 A93 R94 E100	I92-S96 VanDerWaalsContact O-CB 3.23Å; I92-S96 WeakPolarHBondContact O-CB 3.19Å; I92-S96 PolarHBondContact O-N 3.41Å; A93-S96 PolarHBondContact O-N 3.31Å; R94-S96 VanDerWaalsContact C-N 3.27Å; R94-S96 PolarHBondContact O-N 3.45Å; S96-E100 VanDerWaalsContact O-CB 3.31Å; S96-E100 WeakPolarHBondContact O-CB 3.34Å; S96-E100 WeakPolarHBondContact O-CG 3.32Å; S96-E100 PolarHBondContact O-N 3.44Å
97	K	55.7	Low	53.2	Low	128 Å²	128	96.7 Å²	96.7	56%	0.557	52%	0.522	S	S	*	.	H	α-helix	trans	-71.1	-45.6	179.3	-177.5	166.5	176.5	156.1	0	112	A93 R94 M99 E100 D101	A93-K97 WeakPolarHBondContact O-CB 3.06Å; A93-K97 PolarHBondContact O-N 3.45Å; R94-K97 PolarHBondContact O-N 3.05Å; R94-K97 VanDerWaalsContact O-N 3.16Å; K97-M99 VanDerWaalsContact C-N 3.28Å; K97-M99 PolarHBondContact O-N 2.73Å; K97-E100 PolarHBondContact O-N 3.06Å; K97-E100 VanDerWaalsContact O-N 3.07Å; K97-D101 PolarHBondContact O-N 2.94Å
98	D	55.7	Low	53.8	Low	108 Å²	108	94.5 Å²	94.5	58%	0.578	51%	0.507	S	S	*	.	H	α-helix	trans	-65.2	-33.7	176.1	-69.3	-16	0	0	0	111.3	R94 S102	R94-D98 WeakPolarHBondContact O-CB 3.43Å; R94-D98 PolarHBondContact O-N 2.94Å; D98-S102 WeakPolarHBondContact O-CB 3.26Å; D98-S102 PolarHBondContact O-N 2.77Å; D98-S102 VanDerWaalsContact O-N 3.16Å; D98-S102 PolarHBondContact O-OG 3.37Å
99	M	52.8	Low	54.5	Low	99 Å²	99	100.6 Å²	100.6	49%	0.488	53%	0.526	S	S	.	.	H	α-helix	trans	-74.4	-27	172.4	-172.2	163.2	53.8	0	0	113.1	I95 K97 S102 V103	I95-M99 WeakPolarHBondContact O-CB 3.31Å; I95-M99 PolarHBondContact O-N 3.43Å; K97-M99 VanDerWaalsContact C-N 3.28Å; K97-M99 PolarHBondContact O-N 2.73Å; M99-S102 WeakPolarHBondContact CA-OG 3.46Å; M99-V103 HydrophobicContact CG-CG2 4.42Å; M99-V103 WeakPolarHBondContact O-CB 3.22Å; M99-V103 WeakPolarHBondContact O-CG2 3.38Å; M99-V103 PolarHBondContact O-N 2.84Å
100	E	51	Low	55.2	Low	79 Å²	79	99 Å²	99	37%	0.369	51%	0.513	S	S	.	.	H	α-helix	trans	-77.1	-34.4	173.8	-87.9	168.2	175.1	0	0	112.9	S96 K97 K108	S96-E100 VanDerWaalsContact O-CB 3.31Å; S96-E100 WeakPolarHBondContact O-CB 3.34Å; S96-E100 WeakPolarHBondContact O-CG 3.32Å; S96-E100 PolarHBondContact O-N 3.44Å; K97-E100 PolarHBondContact O-N 3.06Å; K97-E100 VanDerWaalsContact O-N 3.07Å; E100-K108 IonicContact OE1-NZ 3.61Å; E100-K108 PolarHBondContact OE1-NZ 2.9Å
101	D	55.7	Low	56.1	Low	131 Å²	131	98.7 Å²	98.7	70%	0.701	51%	0.514	S	S	*	.	H	α-helix	trans	-76.6	-28.2	175.6	-75.7	-21.1	0	0	0	112.3	K97	K97-D101 PolarHBondContact O-N 2.94Å
102	S	55.9	Low	56.9	Low	92 Å²	92	97.3 Å²	97.3	64%	0.643	52%	0.518	S	S	*	.	H	α-helix	trans	-90.4	-20.4	179.6	53.1	0	0	0	0	114.5	D98 M99	D98-S102 WeakPolarHBondContact O-CB 3.26Å; D98-S102 PolarHBondContact O-N 2.77Å; D98-S102 VanDerWaalsContact O-N 3.16Å; D98-S102 PolarHBondContact O-OG 3.37Å; M99-S102 WeakPolarHBondContact CA-OG 3.46Å
103	V	50.4	Low	57.7	Low	61 Å²	61	96 Å²	96	37%	0.37	51%	0.512	S	S	.	.	S	Bend	trans	-120.3	96.3	178.1	-172.1	0	0	0	0	108.4	M99 L105 C107	M99-V103 HydrophobicContact CG-CG2 4.42Å; M99-V103 WeakPolarHBondContact O-CB 3.22Å; M99-V103 WeakPolarHBondContact O-CG2 3.38Å; M99-V103 PolarHBondContact O-N 2.84Å; V103-L105 PolarHBondContact O-N 3.5Å; V103-C107 HydrophobicContact CG1-CB 3.71Å
104	G	46.5	Very low	58.8	Low	54 Å²	54	97.4 Å²	97.4	56%	0.557	52%	0.516	S	S	*	.			trans	-41.8	133	-179.2	0	0	0	0	0	112.7	D106 C107	G104-D106 PolarHBondContact O-N 2.81Å; G104-C107 PolarHBondContact O-N 3.45Å
105	L	51.2	Low	60	Low	140 Å²	140	95 Å²	95	73%	0.733	52%	0.515	S	S	*	.	H	α-helix	trans	-46.2	-22.7	-170	-71.3	161.7	0	0	0	115.4	V103	V103-L105 PolarHBondContact O-N 3.5Å
106	D	52.8	Low	61.2	Low	107 Å²	107	90.3 Å²	90.3	57%	0.572	49%	0.492	S	S	*	.	H	α-helix	trans	-68.9	-37.3	175.5	-71.9	-38.7	0	0	0	113.2	G104 K108 R109 Y110	G104-D106 PolarHBondContact O-N 2.81Å; D106-K108 PolarHBondContact O-N 3.42Å; D106-R109 WeakPolarHBondContact O-CB 3.23Å; D106-R109 PolarHBondContact O-N 3.49Å; D106-Y110 HydrophobicContact CB-CE2 4.35Å; D106-Y110 WeakPolarHBondContact O-CD2 3.48Å; D106-Y110 PolarHBondContact O-N 2.91Å; D106-Y110 VanDerWaalsContact O-N 3.16Å
107	C	55	Low	62.5	Low	75 Å²	75	91.7 Å²	91.7	51%	0.507	50%	0.502	S	S	.	.	H	α-helix	trans	-68.7	-36.5	-172.6	-164.2	0	0	0	0	112.7	V103 G104 R109 Y110 L111	V103-C107 HydrophobicContact CG1-CB 3.71Å; G104-C107 PolarHBondContact O-N 3.45Å; C107-R109 VanDerWaalsContact C-N 3.34Å; C107-Y110 PolarHBondContact O-N 3.31Å; C107-L111 WeakPolarHBondContact O-CB 3.19Å; C107-L111 PolarHBondContact O-N 2.88Å
108	K	57.3	Low	64	Low	100 Å²	100	92.1 Å²	92.1	44%	0.435	50%	0.504	S	S	.	.	H	α-helix	trans	-68	-34.5	176.8	-138.9	174.6	-179.7	177.1	0	111.5	E100 D106 L111 G112	E100-K108 IonicContact OE1-NZ 3.61Å; E100-K108 PolarHBondContact OE1-NZ 2.9Å; D106-K108 PolarHBondContact O-N 3.42Å; K108-L111 PolarHBondContact O-N 2.94Å; K108-G112 PolarHBondContact O-N 3.23Å
109	R	59.9	Low	65.6	Low	157 Å²	157	87.9 Å²	87.9	59%	0.592	48%	0.481	S	S	*	.	H	α-helix	trans	-66.8	-41.9	177.1	-169.6	-177.9	-170.9	-172.7	5.4	111.9	D106 C107 D178	D106-R109 WeakPolarHBondContact O-CB 3.23Å; D106-R109 PolarHBondContact O-N 3.49Å; C107-R109 VanDerWaalsContact C-N 3.34Å; R109-D178 IonicContact CZ-OD2 3.84Å; R109-D178 IonicContact NE-OD2 3.92Å; R109-D178 IonicContact NH2-OD2 3.92Å; R109-D178 PolarHBondContact NH2-OD2 3.27Å
110	Y	64.9	Low	67.2	Low	139 Å²	139	84.2 Å²	84.2	55%	0.545	47%	0.469	S	S	.	.	H	α-helix	trans	-74.2	-37.4	174.4	-69.7	-71.9	0	0	0	111.8	D106 C107 G112 L113 T114	D106-Y110 HydrophobicContact CB-CE2 4.35Å; D106-Y110 WeakPolarHBondContact O-CD2 3.48Å; D106-Y110 PolarHBondContact O-N 2.91Å; D106-Y110 VanDerWaalsContact O-N 3.16Å; C107-Y110 PolarHBondContact O-N 3.31Å; Y110-G112 PolarHBondContact O-N 2.86Å; Y110-L113 CarbonylContact O-C 3.55Å; Y110-L113 PolarHBondContact O-N 3.42Å; Y110-T114 WeakPolarHBondContact O-CB 3.35Å; Y110-T114 VanDerWaalsContact O-CG2 3.26Å; Y110-T114 WeakPolarHBondContact O-CG2 3.38Å; Y110-T114 PolarHBondContact O-N 3.44Å; Y110-T114 PolarHBondContact O-OG1 3.27Å; Y110-T114 VanDerWaalsContact O-OG1 3.06Å
111	L	72.2	Confident	69.1	Low	102 Å²	102	85.3 Å²	85.3	53%	0.534	48%	0.477	S	S	.	.	H	α-helix	trans	-54.9	-47.5	-178.1	-168.7	79.8	0	0	0	113	C107 K108 L113 T114 V115	C107-L111 WeakPolarHBondContact O-CB 3.19Å; C107-L111 PolarHBondContact O-N 2.88Å; K108-L111 PolarHBondContact O-N 2.94Å; L111-L113 VanDerWaalsContact C-N 3.32Å; L111-L113 PolarHBondContact O-N 3.26Å; L111-T114 WeakPolarHBondContact CA-OG1 3.35Å; L111-T114 PolarHBondContact O-N 2.9Å; L111-T114 PolarHBondContact O-OG1 3.31Å; L111-V115 WeakPolarHBondContact O-CB 3.47Å; L111-V115 VanDerWaalsContact O-CG2 3.22Å; L111-V115 WeakPolarHBondContact O-CG2 3.27Å; L111-V115 PolarHBondContact O-N 3.24Å
112	G	73.1	Confident	70.7	Confident	46 Å²	46	81.8 Å²	81.8	47%	0.474	46%	0.458	S	S	.	.	H	α-helix	trans	-66.2	-35.2	178.5	0	0	0	0	0	113	K108 Y110 A116	K108-G112 PolarHBondContact O-N 3.23Å; Y110-G112 PolarHBondContact O-N 2.86Å; G112-A116 VanDerWaalsContact O-CB 3.25Å; G112-A116 WeakPolarHBondContact O-CB 3.49Å; G112-A116 PolarHBondContact O-N 3.16Å; G112-A116 VanDerWaalsContact O-N 3.17Å
113	L	74.8	Confident	72.4	Confident	77 Å²	77	77.7 Å²	77.7	40%	0.403	43%	0.429	S	S	.	.	H	α-helix	trans	-73.5	-40.4	176.7	-177.4	64.6	0	0	0	111.7	Y110 L111 A116 S117 F171	Y110-L113 CarbonylContact O-C 3.55Å; Y110-L113 PolarHBondContact O-N 3.42Å; L111-L113 VanDerWaalsContact C-N 3.32Å; L111-L113 PolarHBondContact O-N 3.26Å; L113-A116 PolarHBondContact O-N 3.03Å; L113-S117 WeakPolarHBondContact O-CB 3.31Å; L113-S117 PolarHBondContact O-N 3.22Å; L113-F171 HydrophobicContact CD1-CD1 4.27Å
114	T	79.1	Confident	74.4	Confident	74 Å²	74	77.2 Å²	77.2	45%	0.454	42%	0.422	S	S	.	.	H	α-helix	trans	-68.7	-43.5	179.7	55.6	0	0	0	0	110.7	Y110 L111 S117 F118	Y110-T114 WeakPolarHBondContact O-CB 3.35Å; Y110-T114 VanDerWaalsContact O-CG2 3.26Å; Y110-T114 WeakPolarHBondContact O-CG2 3.38Å; Y110-T114 PolarHBondContact O-N 3.44Å; Y110-T114 PolarHBondContact O-OG1 3.27Å; Y110-T114 VanDerWaalsContact O-OG1 3.06Å; L111-T114 WeakPolarHBondContact CA-OG1 3.35Å; L111-T114 PolarHBondContact O-N 2.9Å; L111-T114 PolarHBondContact O-OG1 3.31Å; T114-S117 PolarHBondContact O-N 3.4Å; T114-F118 VanDerWaalsContact O-CB 3.23Å; T114-F118 WeakPolarHBondContact O-CB 3.44Å; T114-F118 PolarHBondContact O-N 3.21Å
115	V	82.8	Confident	76.6	Confident	80 Å²	80	78.8 Å²	78.8	49%	0.485	42%	0.417	S	S	.	.	H	α-helix	trans	-62	-46.1	174.7	171.6	0	0	0	0	110.9	L111 S117 F118 L119	L111-V115 WeakPolarHBondContact O-CB 3.47Å; L111-V115 VanDerWaalsContact O-CG2 3.22Å; L111-V115 WeakPolarHBondContact O-CG2 3.27Å; L111-V115 PolarHBondContact O-N 3.24Å; V115-S117 PolarHBondContact O-N 3.24Å; V115-F118 PolarHBondContact O-N 3.02Å; V115-L119 VanDerWaalsContact O-CB 3.31Å; V115-L119 WeakPolarHBondContact O-CB 3.38Å; V115-L119 PolarHBondContact O-N 3.17Å
116	A	82.6	Confident	78.6	Confident	8 Å²	8	72.3 Å²	72.3	7%	0.066	38%	0.384	C	S	.	.	H	α-helix	trans	-65.3	-39.5	178.3	0	0	0	0	0	112.5	G112 L113 G120 F171 L190	G112-A116 VanDerWaalsContact O-CB 3.25Å; G112-A116 WeakPolarHBondContact O-CB 3.49Å; G112-A116 PolarHBondContact O-N 3.16Å; G112-A116 VanDerWaalsContact O-N 3.17Å; L113-A116 PolarHBondContact O-N 3.03Å; A116-G120 PolarHBondContact O-N 3.47Å; A116-F171 HydrophobicContact CB-CE1 3.74Å; A116-F171 HydrophobicContact CB-CZ 3.99Å; A116-L190 HydrophobicContact CB-CD1 3.93Å; A116-L190 HydrophobicContact CB-CD2 3.84Å
117	S	83.2	Confident	80.6	Confident	69 Å²	69	67.2 Å²	67.2	48%	0.483	36%	0.357	S	S	.	.	H	α-helix	trans	-67.6	-42.5	176.5	-171.9	0	0	0	0	111.7	L113 T114 V115 G120 L121	L113-S117 WeakPolarHBondContact O-CB 3.31Å; L113-S117 PolarHBondContact O-N 3.22Å; T114-S117 PolarHBondContact O-N 3.4Å; V115-S117 PolarHBondContact O-N 3.24Å; S117-G120 PolarHBondContact O-N 3.06Å; S117-L121 WeakPolarHBondContact O-CB 3.26Å; S117-L121 PolarHBondContact O-N 3.05Å
118	F	87.5	Confident	82.3	Confident	137 Å²	137	66.4 Å²	66.4	60%	0.601	35%	0.347	S	S	*	.	H	α-helix	trans	-64	-47.5	177.4	179.8	-99.1	0	0	0	110.9	T114 V115 G120 L121 L122	T114-F118 VanDerWaalsContact O-CB 3.23Å; T114-F118 WeakPolarHBondContact O-CB 3.44Å; T114-F118 PolarHBondContact O-N 3.21Å; V115-F118 PolarHBondContact O-N 3.02Å; F118-G120 VanDerWaalsContact C-N 3.33Å; F118-G120 PolarHBondContact O-N 3.22Å; F118-L121 PolarHBondContact O-N 3.12Å; F118-L122 HydrophobicContact CE1-CD1 3.99Å; F118-L122 HydrophobicContact CZ-CD1 4.3Å; F118-L122 WeakPolarHBondContact O-CB 3.32Å; F118-L122 PolarHBondContact O-N 3.36Å
119	L	88.8	Confident	84	Confident	18 Å²	18	63.1 Å²	63.1	9%	0.094	34%	0.338	C	S	.	.	H	α-helix	trans	-64.2	-38.4	177.4	-171.7	66.4	0	0	0	112	V115 L122 A123 L190 I193 F194	V115-L119 VanDerWaalsContact O-CB 3.31Å; V115-L119 WeakPolarHBondContact O-CB 3.38Å; V115-L119 PolarHBondContact O-N 3.17Å; L119-L122 PolarHBondContact O-N 3.44Å; L119-A123 WeakPolarHBondContact O-CB 3.34Å; L119-A123 PolarHBondContact O-N 3.46Å; L119-L190 HydrophobicContact CD2-CB 4.31Å; L119-L190 HydrophobicContact CD2-CD2 4.09Å; L119-L190 VanDerWaalsContact CD2-O 3.22Å; L119-L190 WeakPolarHBondContact CD2-O 3.09Å; L119-I193 HydrophobicContact CD2-CB 4.19Å; L119-I193 HydrophobicContact CD2-CG2 4.06Å; L119-I193 HydrophobicContact CG-CG2 4Å; L119-F194 HydrophobicContact CD1-CB 4.09Å; L119-F194 HydrophobicContact CD1-CD2 3.99Å; L119-F194 HydrophobicContact CD2-CB 4.03Å
120	G	87.3	Confident	85.5	Confident	22 Å²	22	55.6 Å²	55.6	23%	0.227	31%	0.31	C	S	.	.	H	α-helix	trans	-64.4	-42.9	174.9	0	0	0	0	0	112.9	A116 S117 F118 A123 F124	A116-G120 PolarHBondContact O-N 3.47Å; S117-G120 PolarHBondContact O-N 3.06Å; F118-G120 VanDerWaalsContact C-N 3.33Å; F118-G120 PolarHBondContact O-N 3.22Å; G120-A123 PolarHBondContact O-N 2.88Å; G120-F124 WeakPolarHBondContact O-CB 3.39Å; G120-F124 PolarHBondContact O-N 3.02Å
121	L	89.4	Confident	86.8	Confident	102 Å²	102	49.9 Å²	49.9	53%	0.534	29%	0.288	S	S	.	.	H	α-helix	trans	-63.6	-44.6	174.8	-172	111.2	0	0	0	111.1	S117 F118 F124 L125	S117-L121 WeakPolarHBondContact O-CB 3.26Å; S117-L121 PolarHBondContact O-N 3.05Å; F118-L121 PolarHBondContact O-N 3.12Å; L121-F124 PolarHBondContact O-N 2.95Å; L121-L125 HydrophobicContact CD2-CD1 3.7Å; L121-L125 HydrophobicContact CG-CD1 3.95Å; L121-L125 HydrophobicContact CG-CG 4.46Å; L121-L125 WeakPolarHBondContact O-CB 3.34Å; L121-L125 WeakPolarHBondContact O-CG 3.45Å; L121-L125 PolarHBondContact O-N 2.86Å
122	L	90.7	Very high	87.6	Confident	58 Å²	58	49.3 Å²	49.3	30%	0.304	29%	0.285	S	S	.	.	H	α-helix	trans	-59.6	-51.9	176.6	-164.5	158.1	0	0	0	109.8	F118 L119 F124 L125 T126 V197	F118-L122 HydrophobicContact CE1-CD1 3.99Å; F118-L122 HydrophobicContact CZ-CD1 4.3Å; F118-L122 WeakPolarHBondContact O-CB 3.32Å; F118-L122 PolarHBondContact O-N 3.36Å; L119-L122 PolarHBondContact O-N 3.44Å; L122-F124 VanDerWaalsContact C-N 3.27Å; L122-F124 PolarHBondContact O-N 3.47Å; L122-L125 PolarHBondContact O-N 3.15Å; L122-L125 VanDerWaalsContact O-N 3.12Å; L122-T126 HydrophobicContact CD2-CG2 3.62Å; L122-T126 HydrophobicContact CG-CG2 4.49Å; L122-T126 VanDerWaalsContact O-CG2 3.22Å; L122-T126 WeakPolarHBondContact O-CG2 3.29Å; L122-T126 PolarHBondContact O-N 3.16Å; L122-T126 PolarHBondContact O-OG1 2.95Å; L122-V197 HydrophobicContact CD2-CG1 3.35Å
123	A	91.1	Very high	88.4	Confident	6 Å²	6	49 Å²	49	5%	0.05	27%	0.273	C	S	.	.	H	α-helix	trans	-56.4	-38.2	177.3	0	0	0	0	0	112.9	L119 G120 T126 P127 I193 V197 L230	L119-A123 WeakPolarHBondContact O-CB 3.34Å; L119-A123 PolarHBondContact O-N 3.46Å; G120-A123 PolarHBondContact O-N 2.88Å; A123-T126 PolarHBondContact O-OG1 3.37Å; A123-P127 WeakPolarHBondContact O-CD 3.35Å; A123-I193 HydrophobicContact CB-CG2 4.05Å; A123-V197 HydrophobicContact CB-CG2 4.07Å; A123-L230 HydrophobicContact CB-CD1 4.31Å; A123-L230 HydrophobicContact CB-CD2 4.18Å
124	F	92	Very high	88.9	Confident	50 Å²	50	45.4 Å²	45.4	22%	0.219	25%	0.254	C	S	.	.	H	α-helix	trans	-69.8	-39.8	176.1	-179.9	-97.5	0	0	0	113.4	G120 L121 L122 P127 I128 L160 L163 L164	G120-F124 WeakPolarHBondContact O-CB 3.39Å; G120-F124 PolarHBondContact O-N 3.02Å; L121-F124 PolarHBondContact O-N 2.95Å; L122-F124 VanDerWaalsContact C-N 3.27Å; L122-F124 PolarHBondContact O-N 3.47Å; F124-P127 WeakPolarHBondContact O-CD 3.12Å; F124-I128 HydrophobicContact CD1-CD1 4.45Å; F124-I128 HydrophobicContact CE1-CD1 3.98Å; F124-I128 HydrophobicContact CZ-CD1 4.41Å; F124-L160 HydrophobicContact CD2-CD2 4.17Å; F124-L160 HydrophobicContact CE2-CB 3.99Å; F124-L160 HydrophobicContact CE2-CD2 4.24Å; F124-L163 HydrophobicContact CD2-CD2 4.12Å; F124-L164 HydrophobicContact CD2-CB 4.41Å; F124-L164 HydrophobicContact CD2-CD1 4.47Å; F124-L164 HydrophobicContact CE2-CB 3.9Å; F124-L164 HydrophobicContact CE2-CD1 4.28Å; F124-L164 HydrophobicContact CE2-CG 4.49Å; F124-L164 HydrophobicContact CZ-CD1 4.49Å
125	L	93.3	Very high	89.2	Confident	87 Å²	87	43.3 Å²	43.3	46%	0.455	24%	0.242	S	C	.	.	H	α-helix	trans	-77.2	-24.8	-178.6	-69.2	175.9	0	0	0	112.9	L121 L122 I128 A129	L121-L125 HydrophobicContact CD2-CD1 3.7Å; L121-L125 HydrophobicContact CG-CD1 3.95Å; L121-L125 HydrophobicContact CG-CG 4.46Å; L121-L125 WeakPolarHBondContact O-CB 3.34Å; L121-L125 WeakPolarHBondContact O-CG 3.45Å; L121-L125 PolarHBondContact O-N 2.86Å; L122-L125 PolarHBondContact O-N 3.15Å; L122-L125 VanDerWaalsContact O-N 3.12Å; L125-I128 HydrophobicContact CD2-CD1 4.49Å; L125-I128 WeakPolarHBondContact O-CB 3.25Å; L125-I128 PolarHBondContact O-N 2.88Å; L125-A129 PolarHBondContact O-N 2.94Å
126	T	93.8	Very high	89.4	Confident	5 Å²	5	45.8 Å²	45.8	3%	0.031	25%	0.251	C	S	.	.	H	α-helix	trans	-60.3	-45.2	-175.5	45.3	0	0	0	0	116	L122 A123 I128 A129 F130 V197 W201	L122-T126 HydrophobicContact CD2-CG2 3.62Å; L122-T126 HydrophobicContact CG-CG2 4.49Å; L122-T126 VanDerWaalsContact O-CG2 3.22Å; L122-T126 WeakPolarHBondContact O-CG2 3.29Å; L122-T126 PolarHBondContact O-N 3.16Å; L122-T126 PolarHBondContact O-OG1 2.95Å; A123-T126 PolarHBondContact O-OG1 3.37Å; T126-I128 VanDerWaalsContact C-N 3.28Å; T126-I128 PolarHBondContact O-N 3.17Å; T126-A129 WeakPolarHBondContact O-CB 3.22Å; T126-A129 PolarHBondContact O-N 3.46Å; T126-F130 PolarHBondContact O-N 2.83Å; T126-V197 HydrophobicContact CG2-CG1 3.94Å; T126-W201 HydrophobicContact CG2-CZ2 4.16Å
127	P	92.9	Very high	89.5	Confident	0 Å²	0	50.4 Å²	50.4	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-65.7	-32.9	176.6	-21.1	34.9	0	0	0	112.5	A123 F124 F130 I131 L160 L226 V227 L230	A123-P127 WeakPolarHBondContact O-CD 3.35Å; F124-P127 WeakPolarHBondContact O-CD 3.12Å; P127-F130 PolarHBondContact O-N 3.18Å; P127-I131 WeakPolarHBondContact O-CG1 3.23Å; P127-I131 PolarHBondContact O-N 3.34Å; P127-L160 HydrophobicContact CB-CD2 4.43Å; P127-L160 HydrophobicContact CG-CD2 4.16Å; P127-L226 HydrophobicContact CG-CD2 3.99Å; P127-L226 HydrophobicContact CG-CG 4.27Å; P127-V227 HydrophobicContact CB-CG2 3.47Å; P127-V227 VanDerWaalsContact CB-CG2 3.47Å; P127-V227 HydrophobicContact CG-CG2 3.55Å; P127-L230 HydrophobicContact CG-CD1 4.42Å
128	I	92.6	Very high	89.6	Confident	58 Å²	58	48.2 Å²	48.2	30%	0.297	26%	0.255	S	S	.	.	H	α-helix	trans	-66.3	-45.3	175.3	-57.9	173	0	0	0	109.5	F124 L125 T126 F130 I131 L132 L160	F124-I128 HydrophobicContact CD1-CD1 4.45Å; F124-I128 HydrophobicContact CE1-CD1 3.98Å; F124-I128 HydrophobicContact CZ-CD1 4.41Å; L125-I128 HydrophobicContact CD2-CD1 4.49Å; L125-I128 WeakPolarHBondContact O-CB 3.25Å; L125-I128 PolarHBondContact O-N 2.88Å; T126-I128 VanDerWaalsContact C-N 3.28Å; T126-I128 PolarHBondContact O-N 3.17Å; I128-F130 PolarHBondContact O-N 2.9Å; I128-I131 PolarHBondContact O-N 3.34Å; I128-L132 HydrophobicContact CG2-CD1 3.69Å; I128-L132 HydrophobicContact CG2-CG 4.3Å; I128-L132 WeakPolarHBondContact O-CG 3.31Å; I128-L132 PolarHBondContact O-N 3.05Å; I128-L160 HydrophobicContact CD1-CD1 4.24Å; I128-L160 HydrophobicContact CG1-CD1 3.77Å
129	A	91.9	Very high	89.2	Confident	30 Å²	30	50.8 Å²	50.8	25%	0.248	26%	0.26	C	S	.	.	H	α-helix	trans	-58.8	-46.9	175.8	0	0	0	0	0	111.2	L125 T126 I131 L132 L133 W201	L125-A129 PolarHBondContact O-N 2.94Å; T126-A129 WeakPolarHBondContact O-CB 3.22Å; T126-A129 PolarHBondContact O-N 3.46Å; A129-I131 PolarHBondContact O-N 3.5Å; A129-L132 PolarHBondContact O-N 3Å; A129-L132 VanDerWaalsContact O-N 3.16Å; A129-L133 VanDerWaalsContact O-CB 3.31Å; A129-L133 WeakPolarHBondContact O-CB 3.24Å; A129-L133 PolarHBondContact O-N 3.46Å; A129-W201 HydrophobicContact CB-CZ2 4.43Å
130	F	92.3	Very high	88.6	Confident	0 Å²	0	57.8 Å²	57.8	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-60.6	-30.5	-179.1	-74.9	4.5	0	0	0	114.2	T126 P127 I128 P134 W201 Y204 Y222 A223 L226	T126-F130 PolarHBondContact O-N 2.83Å; P127-F130 PolarHBondContact O-N 3.18Å; I128-F130 PolarHBondContact O-N 2.9Å; F130-P134 WeakPolarHBondContact O-CD 3.39Å; F130-W201 AromaticContact CE1-CD2 3.69Å; F130-W201 HydrophobicContact CE1-CD2 3.69Å; F130-W201 AromaticContact CE1-CE2 3.73Å; F130-W201 AromaticContact CE1-CE3 3.85Å; F130-W201 HydrophobicContact CE1-CE3 3.85Å; F130-W201 HydrophobicContact CE1-CG 4.24Å; F130-W201 HydrophobicContact CE1-CH2 4.1Å; F130-W201 AromaticContact CE1-CZ2 3.95Å; F130-W201 HydrophobicContact CE1-CZ2 3.95Å; F130-W201 HydrophobicContact CE1-CZ3 4.05Å; F130-W201 HydrophobicContact CZ-CD2 4.13Å; F130-W201 HydrophobicContact CZ-CG 4.19Å; F130-Y204 HydrophobicContact CB-CD2 4.15Å; F130-Y204 HydrophobicContact CB-CE2 3.66Å; F130-Y204 AromaticContact CD1-CD1 3.92Å; F130-Y204 HydrophobicContact CD1-CD1 3.92Å; F130-Y204 AromaticContact CD1-CD2 3.75Å; F130-Y204 HydrophobicContact CD1-CD2 3.75Å; F130-Y204 AromaticContact CD1-CE1 4Å; F130-Y204 HydrophobicContact CD1-CE1 4Å; F130-Y204 AromaticContact CD1-CE2 3.84Å; F130-Y204 HydrophobicContact CD1-CE2 3.84Å; F130-Y204 AromaticContact CD1-CG 3.8Å; F130-Y204 HydrophobicContact CD1-CG 3.8Å; F130-Y204 AromaticContact CD1-CZ 3.96Å; F130-Y204 AromaticContact CD2-CD2 3.68Å; F130-Y204 HydrophobicContact CD2-CD2 3.68Å; F130-Y204 HydrophobicContact CD2-CE2 4.09Å; F130-Y204 HydrophobicContact CD2-CG 4.25Å; F130-Y204 AromaticContact CE1-CD1 3.83Å; F130-Y204 HydrophobicContact CE1-CD1 3.83Å; F130-Y204 AromaticContact CE1-CD2 3.99Å; F130-Y204 HydrophobicContact CE1-CD2 3.99Å; F130-Y204 HydrophobicContact CE1-CE1 4.35Å; F130-Y204 HydrophobicContact CE1-CE2 4.5Å; F130-Y204 AromaticContact CE1-CG 3.63Å; F130-Y204 HydrophobicContact CE1-CG 3.63Å; F130-Y204 AromaticContact CE2-CD2 3.92Å; F130-Y204 HydrophobicContact CE2-CD2 3.92Å; F130-Y204 HydrophobicContact CE2-CG 4.1Å; F130-Y204 AromaticContact CG-CD2 3.59Å; F130-Y204 HydrophobicContact CG-CD2 3.59Å; F130-Y204 AromaticContact CG-CE2 3.61Å; F130-Y204 HydrophobicContact CG-CE2 3.61Å; F130-Y204 HydrophobicContact CG-CG 4.12Å; F130-Y204 HydrophobicContact CZ-CD1 4.42Å; F130-Y204 HydrophobicContact CZ-CD2 4.08Å; F130-Y204 AromaticContact CZ-CG 3.8Å; F130-Y204 HydrophobicContact CZ-CG 3.8Å; F130-Y204 PolarHBondContact O-OH 3.26Å; F130-Y222 HydrophobicContact CD2-CD1 4.23Å; F130-Y222 HydrophobicContact CD2-CE1 4.24Å; F130-Y222 HydrophobicContact CE2-CD1 4.33Å; F130-Y222 AromaticContact CE2-CE1 3.87Å; F130-Y222 HydrophobicContact CE2-CE1 3.87Å; F130-A223 HydrophobicContact CB-CB 4.1Å; F130-L226 HydrophobicContact CD2-CD2 4.13Å; F130-L226 HydrophobicContact CE2-CD2 3.83Å
131	I	90.6	Very high	88.2	Confident	18 Å²	18	60.2 Å²	60.2	9%	0.092	30%	0.303	C	S	.	.	H	α-helix	trans	-79.8	-40.3	176.6	-68.1	169.9	0	0	0	111.2	P127 I128 A129 P135 F153 V156 Y216 A223	P127-I131 WeakPolarHBondContact O-CG1 3.23Å; P127-I131 PolarHBondContact O-N 3.34Å; I128-I131 PolarHBondContact O-N 3.34Å; A129-I131 PolarHBondContact O-N 3.5Å; I131-P135 VanDerWaalsContact O-CD 3.32Å; I131-P135 WeakPolarHBondContact O-CD 3.32Å; I131-F153 HydrophobicContact CD1-CD1 4.43Å; I131-F153 HydrophobicContact CD1-CE1 4.41Å; I131-F153 HydrophobicContact CG2-CD1 4.3Å; I131-F153 HydrophobicContact CG2-CE1 3.58Å; I131-F153 HydrophobicContact CG2-CZ 4.49Å; I131-V156 HydrophobicContact CD1-CG1 4Å; I131-V156 HydrophobicContact CD1-CG2 4.38Å; I131-Y216 PolarHBondContact O-OH 2.96Å; I131-A223 HydrophobicContact CD1-CB 4.16Å; I131-A223 HydrophobicContact CG1-CB 3.81Å
132	L	89.7	Confident	87.8	Confident	90 Å²	90	56.9 Å²	56.9	47%	0.471	29%	0.286	S	S	.	.	H	α-helix	trans	-85.4	-25.6	-174.3	-65.2	-179.8	0	0	0	114.3	I128 A129 P135 I136	I128-L132 HydrophobicContact CG2-CD1 3.69Å; I128-L132 HydrophobicContact CG2-CG 4.3Å; I128-L132 WeakPolarHBondContact O-CG 3.31Å; I128-L132 PolarHBondContact O-N 3.05Å; A129-L132 PolarHBondContact O-N 3Å; A129-L132 VanDerWaalsContact O-N 3.16Å; L132-P135 VanDerWaalsContact O-CD 3.27Å; L132-P135 WeakPolarHBondContact O-CD 2.95Å; L132-P135 WeakPolarHBondContact O-CG 3.46Å; L132-I136 HydrophobicContact CB-CD1 4.3Å; L132-I136 VanDerWaalsContact O-CD1 3.26Å; L132-I136 WeakPolarHBondContact O-CD1 3.49Å; L132-I136 WeakPolarHBondContact O-CG1 3.15Å; L132-I136 PolarHBondContact O-N 3.23Å
133	L	89.4	Confident	87.4	Confident	41 Å²	41	59.4 Å²	59.4	22%	0.215	30%	0.296	C	S	.	.	H	α-helix	trans	-61.8	-47.9	-176	-129.7	149.3	0	0	0	113.6	A129 I136 L137 W201 L209	A129-L133 VanDerWaalsContact O-CB 3.31Å; A129-L133 WeakPolarHBondContact O-CB 3.24Å; A129-L133 PolarHBondContact O-N 3.46Å; L133-I136 PolarHBondContact O-N 2.93Å; L133-L137 HydrophobicContact CD2-CD1 3.64Å; L133-L137 HydrophobicContact CD2-CD2 3.88Å; L133-L137 HydrophobicContact CD2-CG 4.3Å; L133-L137 PolarHBondContact O-N 2.87Å; L133-W201 HydrophobicContact CD1-CH2 4.27Å; L133-L209 HydrophobicContact CD2-CD2 3.77Å
134	P	86.6	Confident	86.7	Confident	0 Å²	0	65.1 Å²	65.1	0%	0	33%	0.333	C	S	.	.	H	α-helix	trans	-61.1	-48.2	-178.6	-20.9	32.1	0	0	0	114.4	F130 I136 L137 W138 L142 Y204 I219	F130-P134 WeakPolarHBondContact O-CD 3.39Å; P134-I136 PolarHBondContact O-N 3.12Å; P134-L137 PolarHBondContact O-N 3.32Å; P134-W138 HydrophobicContact CB-CH2 4.02Å; P134-W138 HydrophobicContact CB-CZ2 4.12Å; P134-W138 HydrophobicContact CB-CZ3 4.42Å; P134-W138 PolarHBondContact O-N 2.95Å; P134-L142 HydrophobicContact CB-CD1 4.31Å; P134-L142 HydrophobicContact CB-CD2 4.17Å; P134-Y204 VanDerWaalsContact CD-OH 3.25Å; P134-Y204 WeakPolarHBondContact CD-OH 3.48Å; P134-Y204 VanDerWaalsContact CG-OH 3.3Å; P134-Y204 WeakPolarHBondContact CG-OH 3.45Å; P134-I219 HydrophobicContact CB-CD1 4.2Å; P134-I219 HydrophobicContact CG-CD1 3.97Å; P134-I219 HydrophobicContact CG-CG2 4.08Å
135	P	84.9	Confident	86	Confident	31 Å²	31	64.8 Å²	64.8	20%	0.201	34%	0.336	C	S	.	.	H	α-helix	trans	-69.3	-15	177.7	27.1	-34.3	0	0	0	113.8	I131 L132 R139	I131-P135 VanDerWaalsContact O-CD 3.32Å; I131-P135 WeakPolarHBondContact O-CD 3.32Å; L132-P135 VanDerWaalsContact O-CD 3.27Å; L132-P135 WeakPolarHBondContact O-CD 2.95Å; L132-P135 WeakPolarHBondContact O-CG 3.46Å; P135-R139 WeakPolarHBondContact O-CB 3.25Å
136	I	87.3	Confident	85.5	Confident	132 Å²	132	62.8 Å²	62.8	68%	0.677	34%	0.337	S	S	*	.	H	α-helix	trans	-82	-38.9	172.4	-67.7	167.6	0	0	0	111	L132 L133 P134	L132-I136 HydrophobicContact CB-CD1 4.3Å; L132-I136 VanDerWaalsContact O-CD1 3.26Å; L132-I136 WeakPolarHBondContact O-CD1 3.49Å; L132-I136 WeakPolarHBondContact O-CG1 3.15Å; L132-I136 PolarHBondContact O-N 3.23Å; L133-I136 PolarHBondContact O-N 2.93Å; P134-I136 PolarHBondContact O-N 3.12Å
137	L	84.9	Confident	85	Confident	105 Å²	105	68.4 Å²	68.4	55%	0.55	37%	0.371	S	S	.	.	H	α-helix	trans	-87	-38.5	-173.2	-102.7	68.5	0	0	0	114.2	L133 P134 L209	L133-L137 HydrophobicContact CD2-CD1 3.64Å; L133-L137 HydrophobicContact CD2-CD2 3.88Å; L133-L137 HydrophobicContact CD2-CG 4.3Å; L133-L137 PolarHBondContact O-N 2.87Å; P134-L137 PolarHBondContact O-N 3.32Å; L137-L209 HydrophobicContact CD2-CD2 4.39Å
138	W	85.4	Confident	84.6	Confident	23 Å²	23	73.2 Å²	73.2	9%	0.087	40%	0.396	C	S	.	.			trans	-149.5	53.5	-174.2	28.7	-89.9	0	0	0	112.6	P134 D140 E141 L142 D213 I219	P134-W138 HydrophobicContact CB-CH2 4.02Å; P134-W138 HydrophobicContact CB-CZ2 4.12Å; P134-W138 HydrophobicContact CB-CZ3 4.42Å; P134-W138 PolarHBondContact O-N 2.95Å; W138-D140 VanDerWaalsContact C-N 3.26Å; W138-D140 PolarHBondContact O-N 2.87Å; W138-D140 VanDerWaalsContact O-N 3.17Å; W138-E141 PolarHBondContact O-N 3.35Å; W138-E141 VanDerWaalsContact O-N 3.12Å; W138-L142 HydrophobicContact CD2-CD1 4.07Å; W138-L142 HydrophobicContact CE3-CD1 3.22Å; W138-L142 HydrophobicContact CE3-CG 4.37Å; W138-L142 HydrophobicContact CH2-CD1 4.49Å; W138-L142 HydrophobicContact CZ3-CD1 3.47Å; W138-L142 VanDerWaalsContact CZ3-CD1 3.47Å; W138-L142 HydrophobicContact CZ3-CG 4.23Å; W138-L142 WeakPolarHBondContact O-CD1 3.35Å; W138-D213 WeakPolarHBondContact CH2-O 3.21Å; W138-D213 WeakPolarHBondContact CZ3-O 3.22Å; W138-I219 HydrophobicContact CH2-CD1 4.15Å
139	R	77.4	Confident	84.2	Confident	190 Å²	190	70.4 Å²	70.4	72%	0.717	38%	0.382	S	S	*	.	G	3₁₀ helix	trans	-50.7	-40	-177.6	-162.8	178.9	-177	125.2	-0.3	114.5	P135 E141 L142	P135-R139 WeakPolarHBondContact O-CB 3.25Å; R139-E141 PolarHBondContact O-N 3.22Å; R139-L142 PolarHBondContact O-N 3.18Å
140	D	77.8	Confident	83.9	Confident	165 Å²	165	74.7 Å²	74.7	88%	0.882	40%	0.397	S	S	*	.	G	3₁₀ helix	trans	-75.7	-13.4	-172.9	-57.1	-37.8	0	0	0	113	W138	W138-D140 VanDerWaalsContact C-N 3.26Å; W138-D140 PolarHBondContact O-N 2.87Å; W138-D140 VanDerWaalsContact O-N 3.17Å
141	E	77.9	Confident	83.7	Confident	73 Å²	73	76.7 Å²	76.7	34%	0.341	42%	0.417	S	S	.	.	G	3₁₀ helix	trans	-101.2	-5.1	179.5	-62.5	-167.1	-148.8	0	0	113.5	W138 R139 R214	W138-E141 PolarHBondContact O-N 3.35Å; W138-E141 VanDerWaalsContact O-N 3.12Å; R139-E141 PolarHBondContact O-N 3.22Å; E141-R214 WeakPolarHBondContact O-CD 3.44Å; E141-R214 WeakPolarHBondContact O-CG 3.49Å; E141-R214 IonicContact OE2-CZ 2.88Å; E141-R214 IonicContact OE2-NE 2.77Å; E141-R214 PolarHBondContact OE2-NE 3.47Å; E141-R214 IonicContact OE2-NH2 2.64Å; E141-R214 PolarHBondContact OE2-NH2 2.89Å
142	L	81.8	Confident	83.7	Confident	32 Å²	32	77.4 Å²	77.4	17%	0.168	42%	0.421	C	S	.	.	S	Bend	trans	-79.4	136.7	-178.7	-95.2	78.5	0	0	0	112	P134 W138 R139 Y216	P134-L142 HydrophobicContact CB-CD1 4.31Å; P134-L142 HydrophobicContact CB-CD2 4.17Å; W138-L142 HydrophobicContact CD2-CD1 4.07Å; W138-L142 HydrophobicContact CE3-CD1 3.22Å; W138-L142 HydrophobicContact CE3-CG 4.37Å; W138-L142 HydrophobicContact CH2-CD1 4.49Å; W138-L142 HydrophobicContact CZ3-CD1 3.47Å; W138-L142 VanDerWaalsContact CZ3-CD1 3.47Å; W138-L142 HydrophobicContact CZ3-CG 4.23Å; W138-L142 WeakPolarHBondContact O-CD1 3.35Å; R139-L142 PolarHBondContact O-N 3.18Å; L142-Y216 HydrophobicContact CD2-CD1 4.42Å; L142-Y216 HydrophobicContact CD2-CD2 3.43Å; L142-Y216 VanDerWaalsContact CD2-CD2 3.43Å; L142-Y216 HydrophobicContact CD2-CE2 3.99Å; L142-Y216 HydrophobicContact CD2-CG 3.71Å
143	E	82.2	Confident	83.6	Confident	112 Å²	112	76 Å²	76	52%	0.523	41%	0.411	S	S	.	.	P	Polyproline II helix	trans	-68.2	138.7	169.2	-67.1	-179.7	167.2	0	0	111	C145 R214	E143-C145 PolarHBondContact O-N 2.95Å; E143-R214 PolarHBondContact N-O 3.29Å
144	P	76.6	Confident	83.7	Confident	126 Å²	126	78.7 Å²	78.7	82%	0.818	43%	0.425	S	S	*	.	P	Polyproline II helix	trans	-64.6	125.1	179.1	25.7	-32.7	0	0	0	110.4	G146	P144-G146 PolarHBondContact O-N 3.4Å
145	C	77.5	Confident	83.9	Confident	42 Å²	42	80.6 Å²	80.6	28%	0.284	44%	0.438	S	S	.	.	P	Polyproline II helix	trans	-72.2	126.5	177.1	-119.4	0	0	0	0	110.6	E143 C149 Y216	E143-C145 PolarHBondContact O-N 2.95Å; C145-C149 HydrophobicContact CB-CB 3.49Å; C145-C149 VanDerWaalsContact CB-CB 3.49Å; C145-C149 WeakPolarHBondContact CB-SG 3.45Å; C145-C149 WeakPolarHBondContact SG-CB 3.3Å; C145-C149 CovalentContact SG-SG 2Å; C145-C149 PolarHBondContact SG-SG 2.75Å; C145-Y216 HydrophobicContact CB-CD1 3.78Å; C145-Y216 HydrophobicContact CB-CE1 4.3Å; C145-Y216 WeakPolarHBondContact SG-CD1 3.33Å
146	G	82.1	Confident	84.3	Confident	46 Å²	46	79.5 Å²	79.5	47%	0.474	43%	0.431	S	S	.	.			trans	-77.7	-172	173.4	0	0	0	0	0	113.4	P144 I148 C149	P144-G146 PolarHBondContact O-N 3.4Å; G146-I148 PolarHBondContact O-N 3.05Å; G146-I148 VanDerWaalsContact O-N 3.08Å; G146-C149 WeakPolarHBondContact O-CB 3.33Å; G146-C149 PolarHBondContact O-N 3.44Å
147	T	82.7	Confident	84.5	Confident	123 Å²	123	76.1 Å²	76.1	76%	0.755	42%	0.422	S	S	*	.	H	α-helix	trans	-59	-22	-179.5	53	0	0	0	0	114.5	C149 E150 G151	T147-C149 VanDerWaalsContact C-N 3.29Å; T147-C149 PolarHBondContact O-N 2.9Å; T147-E150 PolarHBondContact O-N 3.39Å; T147-G151 PolarHBondContact O-N 2.87Å
148	I	84.1	Confident	84.9	Confident	100 Å²	100	77.5 Å²	77.5	51%	0.513	42%	0.424	S	S	.	.	H	α-helix	trans	-63.2	-38.4	175.8	-60.8	172.2	0	0	0	110.6	G146 G151 L152	G146-I148 PolarHBondContact O-N 3.05Å; G146-I148 VanDerWaalsContact O-N 3.08Å; I148-G151 PolarHBondContact O-N 3.14Å; I148-L152 HydrophobicContact CG2-CD1 4.49Å; I148-L152 WeakPolarHBondContact O-CG 3.41Å; I148-L152 PolarHBondContact O-N 3.38Å
149	C	84.5	Confident	85.3	Confident	0 Å²	0	78.4 Å²	78.4	0%	0	43%	0.429	C	S	.	.	H	α-helix	trans	-71.2	-36.9	-179	-53.8	0	0	0	0	112.4	C145 G146 T147 G151 L152 F153	C145-C149 HydrophobicContact CB-CB 3.49Å; C145-C149 VanDerWaalsContact CB-CB 3.49Å; C145-C149 WeakPolarHBondContact CB-SG 3.45Å; C145-C149 WeakPolarHBondContact SG-CB 3.3Å; C145-C149 CovalentContact SG-SG 2Å; C145-C149 PolarHBondContact SG-SG 2.75Å; G146-C149 WeakPolarHBondContact O-CB 3.33Å; G146-C149 PolarHBondContact O-N 3.44Å; T147-C149 VanDerWaalsContact C-N 3.29Å; T147-C149 PolarHBondContact O-N 2.9Å; C149-G151 PolarHBondContact O-N 3.01Å; C149-L152 CarbonylContact O-C 3.56Å; C149-L152 WeakPolarHBondContact O-CA 3.25Å; C149-L152 WeakPolarHBondContact O-CB 3.35Å; C149-L152 PolarHBondContact O-N 3.3Å; C149-F153 HydrophobicContact CB-CD2 4.44Å; C149-F153 HydrophobicContact CB-CE2 3.89Å; C149-F153 HydrophobicContact CB-CZ 4.48Å; C149-F153 WeakPolarHBondContact O-CD2 3.08Å; C149-F153 WeakPolarHBondContact O-CG 3.34Å; C149-F153 PolarHBondContact O-N 2.97Å
150	E	86.2	Confident	86	Confident	120 Å²	120	70 Å²	70	56%	0.561	40%	0.398	S	S	*	.	H	α-helix	trans	-53.9	-44.3	173	-65.1	-66.1	163.3	0	0	111	T147 L152 F153 I154	T147-E150 PolarHBondContact O-N 3.39Å; E150-L152 PolarHBondContact O-N 3.47Å; E150-F153 PolarHBondContact O-N 3.44Å; E150-I154 WeakPolarHBondContact O-CG1 3.46Å; E150-I154 PolarHBondContact O-N 2.76Å; E150-I154 VanDerWaalsContact O-N 3.16Å
151	G	88.3	Confident	86.7	Confident	42 Å²	42	66.6 Å²	66.6	43%	0.433	38%	0.379	S	S	.	.	H	α-helix	trans	-63.9	-38.9	174	0	0	0	0	0	113.6	T147 I148 C149 S155	T147-G151 PolarHBondContact O-N 2.87Å; I148-G151 PolarHBondContact O-N 3.14Å; C149-G151 PolarHBondContact O-N 3.01Å; G151-S155 WeakPolarHBondContact O-CB 3.29Å; G151-S155 PolarHBondContact O-N 2.85Å
152	L	89.8	Confident	87.3	Confident	33 Å²	33	66.8 Å²	66.8	17%	0.173	38%	0.382	C	S	.	.	H	α-helix	trans	-68.1	-37.7	176.8	-65.9	172.8	0	0	0	112.2	I148 C149 E150 S155 V156 V220 Q221 V224	I148-L152 HydrophobicContact CG2-CD1 4.49Å; I148-L152 WeakPolarHBondContact O-CG 3.41Å; I148-L152 PolarHBondContact O-N 3.38Å; C149-L152 CarbonylContact O-C 3.56Å; C149-L152 WeakPolarHBondContact O-CA 3.25Å; C149-L152 WeakPolarHBondContact O-CB 3.35Å; C149-L152 PolarHBondContact O-N 3.3Å; E150-L152 PolarHBondContact O-N 3.47Å; L152-S155 WeakPolarHBondContact O-CB 3.45Å; L152-S155 PolarHBondContact O-N 3.39Å; L152-V156 WeakPolarHBondContact O-CG2 3.43Å; L152-V156 PolarHBondContact O-N 2.98Å; L152-V220 HydrophobicContact CB-CG1 3.63Å; L152-V220 HydrophobicContact CD1-CB 4.48Å; L152-V220 HydrophobicContact CD1-CG1 3.99Å; L152-V220 HydrophobicContact CG-CG1 4.46Å; L152-Q221 HydrophobicContact CD1-CG 3.7Å; L152-V224 HydrophobicContact CB-CG2 4.23Å; L152-V224 HydrophobicContact CD2-CG2 4.06Å
153	F	89	Confident	87.7	Confident	59 Å²	59	65.7 Å²	65.7	26%	0.259	38%	0.376	S	S	.	.	H	α-helix	trans	-63.5	-44.4	175.5	-67.7	-51.6	0	0	0	111.9	I131 C149 E150 S155 V156 A157 Y216 V220	I131-F153 HydrophobicContact CD1-CD1 4.43Å; I131-F153 HydrophobicContact CD1-CE1 4.41Å; I131-F153 HydrophobicContact CG2-CD1 4.3Å; I131-F153 HydrophobicContact CG2-CE1 3.58Å; I131-F153 HydrophobicContact CG2-CZ 4.49Å; C149-F153 HydrophobicContact CB-CD2 4.44Å; C149-F153 HydrophobicContact CB-CE2 3.89Å; C149-F153 HydrophobicContact CB-CZ 4.48Å; C149-F153 WeakPolarHBondContact O-CD2 3.08Å; C149-F153 WeakPolarHBondContact O-CG 3.34Å; C149-F153 PolarHBondContact O-N 2.97Å; E150-F153 PolarHBondContact O-N 3.44Å; F153-S155 VanDerWaalsContact C-N 3.31Å; F153-S155 PolarHBondContact O-N 2.78Å; F153-V156 PolarHBondContact O-N 2.87Å; F153-A157 WeakPolarHBondContact O-CB 3.49Å; F153-A157 PolarHBondContact O-N 3.46Å; F153-Y216 AromaticContact CZ-CE1 3.74Å; F153-Y216 HydrophobicContact CZ-CE1 3.74Å; F153-Y216 AromaticContact CZ-CZ 3.99Å; F153-V220 HydrophobicContact CD1-CG1 4.36Å; F153-V220 HydrophobicContact CE1-CG1 3.99Å; F153-V220 HydrophobicContact CE1-CG2 3.76Å; F153-V220 HydrophobicContact CZ-CG1 4.43Å; F153-V220 HydrophobicContact CZ-CG2 3.76Å
154	I	90.2	Very high	88	Confident	99 Å²	99	64.6 Å²	64.6	51%	0.508	37%	0.374	S	S	.	.	H	α-helix	trans	-59.7	-46	174.6	-65.8	167.7	0	0	0	109.9	E150 V156 A157 F158	E150-I154 WeakPolarHBondContact O-CG1 3.46Å; E150-I154 PolarHBondContact O-N 2.76Å; E150-I154 VanDerWaalsContact O-N 3.16Å; I154-V156 PolarHBondContact O-N 3.48Å; I154-A157 PolarHBondContact O-N 3.49Å; I154-F158 HydrophobicContact CG2-CD2 3.66Å; I154-F158 HydrophobicContact CG2-CE2 3.63Å; I154-F158 VanDerWaalsContact O-CD2 3.29Å; I154-F158 WeakPolarHBondContact O-CD2 3.08Å; I154-F158 PolarHBondContact O-N 2.99Å
155	S	91.5	Very high	88.6	Confident	40 Å²	40	63.3 Å²	63.3	28%	0.28	36%	0.359	S	S	.	.	H	α-helix	trans	-58.7	-47.5	177.3	-174.4	0	0	0	0	112.3	G151 L152 F153 A157 F158 K159	G151-S155 WeakPolarHBondContact O-CB 3.29Å; G151-S155 PolarHBondContact O-N 2.85Å; L152-S155 WeakPolarHBondContact O-CB 3.45Å; L152-S155 PolarHBondContact O-N 3.39Å; F153-S155 VanDerWaalsContact C-N 3.31Å; F153-S155 PolarHBondContact O-N 2.78Å; S155-A157 PolarHBondContact O-N 3.27Å; S155-F158 PolarHBondContact O-N 3.3Å; S155-K159 WeakPolarHBondContact O-CB 3.21Å; S155-K159 WeakPolarHBondContact O-CG 3.3Å; S155-K159 PolarHBondContact O-N 3.32Å; S155-K159 VanDerWaalsContact OG-CE 3.3Å; S155-K159 WeakPolarHBondContact OG-CE 3.39Å
156	V	92.5	Very high	88.8	Confident	7 Å²	7	61.9 Å²	61.9	4%	0.042	35%	0.351	C	S	.	.	H	α-helix	trans	-61.4	-44.6	176.7	170.1	0	0	0	0	111	I131 L152 F153 I154 F158 K159 L160 V224 V227	I131-V156 HydrophobicContact CD1-CG1 4Å; I131-V156 HydrophobicContact CD1-CG2 4.38Å; L152-V156 WeakPolarHBondContact O-CG2 3.43Å; L152-V156 PolarHBondContact O-N 2.98Å; F153-V156 PolarHBondContact O-N 2.87Å; I154-V156 PolarHBondContact O-N 3.48Å; V156-F158 PolarHBondContact O-N 3.32Å; V156-K159 PolarHBondContact O-N 2.84Å; V156-L160 HydrophobicContact CG1-CD1 3.71Å; V156-L160 HydrophobicContact CG1-CG 4.1Å; V156-L160 VanDerWaalsContact O-CB 3.31Å; V156-L160 WeakPolarHBondContact O-CB 3.37Å; V156-L160 VanDerWaalsContact O-CG 3.32Å; V156-L160 WeakPolarHBondContact O-CG 3.32Å; V156-L160 PolarHBondContact O-N 3.27Å; V156-V224 HydrophobicContact CG2-CB 4.29Å; V156-V224 HydrophobicContact CG2-CG2 3.39Å; V156-V227 HydrophobicContact CG1-CG2 4.4Å
157	A	92.8	Very high	88.7	Confident	61 Å²	61	61.4 Å²	61.4	50%	0.504	34%	0.339	S	S	.	.	H	α-helix	trans	-60	-47.6	179.5	0	0	0	0	0	112	F153 I154 S155 L161	F153-A157 WeakPolarHBondContact O-CB 3.49Å; F153-A157 PolarHBondContact O-N 3.46Å; I154-A157 PolarHBondContact O-N 3.49Å; S155-A157 PolarHBondContact O-N 3.27Å; A157-L161 WeakPolarHBondContact O-CB 3.31Å; A157-L161 PolarHBondContact O-N 3.49Å
158	F	92.8	Very high	88.7	Confident	135 Å²	135	62.8 Å²	62.8	59%	0.592	33%	0.33	S	S	*	.	H	α-helix	trans	-64.4	-44.4	176.7	-84.4	-70.9	0	0	0	112.4	I154 S155 V156 L161 I162	I154-F158 HydrophobicContact CG2-CD2 3.66Å; I154-F158 HydrophobicContact CG2-CE2 3.63Å; I154-F158 VanDerWaalsContact O-CD2 3.29Å; I154-F158 WeakPolarHBondContact O-CD2 3.08Å; I154-F158 PolarHBondContact O-N 2.99Å; S155-F158 PolarHBondContact O-N 3.3Å; V156-F158 PolarHBondContact O-N 3.32Å; F158-L161 PolarHBondContact O-N 3.35Å; F158-I162 WeakPolarHBondContact O-CG1 3.39Å; F158-I162 PolarHBondContact O-N 3.29Å
159	K	94.4	Very high	88.4	Confident	42 Å²	42	60.4 Å²	60.4	18%	0.183	33%	0.326	C	S	.	.	H	α-helix	trans	-64	-41.5	179.2	-72.9	175.5	-177.4	-178.1	0	112.2	S155 V156 I162 L163 V227 D228 L231	S155-K159 WeakPolarHBondContact O-CB 3.21Å; S155-K159 WeakPolarHBondContact O-CG 3.3Å; S155-K159 PolarHBondContact O-N 3.32Å; S155-K159 VanDerWaalsContact OG-CE 3.3Å; S155-K159 WeakPolarHBondContact OG-CE 3.39Å; V156-K159 PolarHBondContact O-N 2.84Å; K159-I162 PolarHBondContact O-N 3.49Å; K159-L163 WeakPolarHBondContact O-CB 3.4Å; K159-L163 PolarHBondContact O-N 3.33Å; K159-V227 HydrophobicContact CB-CG1 3.4Å; K159-V227 HydrophobicContact CD-CG1 4.08Å; K159-V227 HydrophobicContact CG-CG1 4.35Å; K159-D228 WeakPolarHBondContact CD-OD1 3.36Å; K159-D228 WeakPolarHBondContact CE-OD1 3.29Å; K159-D228 IonicContact NZ-OD1 3.76Å; K159-D228 PolarHBondContact NZ-OD1 3.33Å; K159-D228 IonicContact NZ-OD2 3.18Å; K159-D228 PolarHBondContact NZ-OD2 2Å; K159-L231 HydrophobicContact CB-CD1 3.68Å; K159-L231 HydrophobicContact CD-CD1 4.19Å; K159-L231 HydrophobicContact CG-CD1 3.72Å
160	L	91.9	Very high	87.8	Confident	13 Å²	13	62.9 Å²	62.9	7%	0.068	34%	0.339	C	S	.	.	H	α-helix	trans	-64.8	-38.9	174.2	-75.7	178.8	0	0	0	111.9	F124 P127 I128 V156 L163 L164 V227	F124-L160 HydrophobicContact CD2-CD2 4.17Å; F124-L160 HydrophobicContact CE2-CB 3.99Å; F124-L160 HydrophobicContact CE2-CD2 4.24Å; P127-L160 HydrophobicContact CB-CD2 4.43Å; P127-L160 HydrophobicContact CG-CD2 4.16Å; I128-L160 HydrophobicContact CD1-CD1 4.24Å; I128-L160 HydrophobicContact CG1-CD1 3.77Å; V156-L160 HydrophobicContact CG1-CD1 3.71Å; V156-L160 HydrophobicContact CG1-CG 4.1Å; V156-L160 VanDerWaalsContact O-CB 3.31Å; V156-L160 WeakPolarHBondContact O-CB 3.37Å; V156-L160 VanDerWaalsContact O-CG 3.32Å; V156-L160 WeakPolarHBondContact O-CG 3.32Å; V156-L160 PolarHBondContact O-N 3.27Å; L160-L163 PolarHBondContact O-N 3.18Å; L160-L164 WeakPolarHBondContact O-CB 3.06Å; L160-L164 PolarHBondContact O-N 3.46Å; L160-V227 HydrophobicContact CD2-CG1 4.43Å; L160-V227 HydrophobicContact CD2-CG2 4.16Å; L160-V227 HydrophobicContact CG-CG2 4.43Å
161	L	92.3	Very high	86.9	Confident	93 Å²	93	61.1 Å²	61.1	49%	0.487	33%	0.329	S	S	.	.	H	α-helix	trans	-62.6	-44.1	175	-178.6	144.3	0	0	0	111.6	A157 F158 L163 L164 I165	A157-L161 WeakPolarHBondContact O-CB 3.31Å; A157-L161 PolarHBondContact O-N 3.49Å; F158-L161 PolarHBondContact O-N 3.35Å; L161-L163 VanDerWaalsContact C-N 3.33Å; L161-L163 PolarHBondContact O-N 2.9Å; L161-L164 PolarHBondContact O-N 2.74Å; L161-I165 HydrophobicContact CD2-CD1 3.55Å; L161-I165 HydrophobicContact CG-CD1 4.2Å; L161-I165 WeakPolarHBondContact O-CG1 3.27Å; L161-I165 PolarHBondContact O-N 3.01Å
162	I	90.7	Very high	85.6	Confident	77 Å²	77	66.4 Å²	66.4	40%	0.395	34%	0.341	S	S	.	.	H	α-helix	trans	-61	-45.1	174.8	-67.7	166.4	0	0	0	110.3	F158 K159 L164 I165 G166 L231	F158-I162 WeakPolarHBondContact O-CG1 3.39Å; F158-I162 PolarHBondContact O-N 3.29Å; K159-I162 PolarHBondContact O-N 3.49Å; I162-L164 VanDerWaalsContact C-N 3.34Å; I162-L164 PolarHBondContact O-N 2.62Å; I162-I165 PolarHBondContact O-N 3.18Å; I162-G166 PolarHBondContact O-N 3.45Å; I162-L231 HydrophobicContact CB-CD2 4.47Å; I162-L231 HydrophobicContact CG2-CD2 4.01Å
163	L	90.1	Very high	84.3	Confident	9 Å²	9	71 Å²	71	5%	0.047	36%	0.356	C	S	.	.	H	α-helix	trans	-63.8	-38.5	178.7	-171.9	136.3	0	0	0	112.1	F124 K159 L160 L161 T167 L230 L231	F124-L163 HydrophobicContact CD2-CD2 4.12Å; K159-L163 WeakPolarHBondContact O-CB 3.4Å; K159-L163 PolarHBondContact O-N 3.33Å; L160-L163 PolarHBondContact O-N 3.18Å; L161-L163 VanDerWaalsContact C-N 3.33Å; L161-L163 PolarHBondContact O-N 2.9Å; L163-T167 HydrophobicContact CD2-CG2 4.27Å; L163-T167 HydrophobicContact CG-CG2 4.46Å; L163-T167 WeakPolarHBondContact O-CB 3.47Å; L163-T167 VanDerWaalsContact O-CG2 3.25Å; L163-T167 WeakPolarHBondContact O-CG2 3.35Å; L163-T167 PolarHBondContact O-N 3.09Å; L163-T167 PolarHBondContact O-OG1 2.84Å; L163-L230 HydrophobicContact CD1-CB 3.61Å; L163-L231 HydrophobicContact CB-CD2 4.02Å; L163-L231 HydrophobicContact CD1-CD2 4.33Å; L163-L231 HydrophobicContact CD1-CG 4.43Å
164	L	89.4	Confident	82.7	Confident	90 Å²	90	77.5 Å²	77.5	47%	0.471	38%	0.384	S	S	.	.	H	α-helix	trans	-64.5	-49	175.3	-177	68	0	0	0	111.6	F124 L160 L161 I162 G166 T167 W168	F124-L164 HydrophobicContact CD2-CB 4.41Å; F124-L164 HydrophobicContact CD2-CD1 4.47Å; F124-L164 HydrophobicContact CE2-CB 3.9Å; F124-L164 HydrophobicContact CE2-CD1 4.28Å; F124-L164 HydrophobicContact CE2-CG 4.49Å; F124-L164 HydrophobicContact CZ-CD1 4.49Å; L160-L164 WeakPolarHBondContact O-CB 3.06Å; L160-L164 PolarHBondContact O-N 3.46Å; L161-L164 PolarHBondContact O-N 2.74Å; I162-L164 VanDerWaalsContact C-N 3.34Å; I162-L164 PolarHBondContact O-N 2.62Å; L164-G166 VanDerWaalsContact C-N 3.33Å; L164-G166 PolarHBondContact O-N 3.3Å; L164-T167 PolarHBondContact O-OG1 2.84Å; L164-W168 WeakPolarHBondContact O-CB 3.38Å; L164-W168 PolarHBondContact O-N 3.05Å
165	I	87.4	Confident	81	Confident	99 Å²	99	78.8 Å²	78.8	51%	0.508	38%	0.382	S	S	.	.	H	α-helix	trans	-63.3	-43.2	177.9	-66.6	171.9	0	0	0	110.4	L161 I162 W168 A169	L161-I165 HydrophobicContact CD2-CD1 3.55Å; L161-I165 HydrophobicContact CG-CD1 4.2Å; L161-I165 WeakPolarHBondContact O-CG1 3.27Å; L161-I165 PolarHBondContact O-N 3.01Å; I162-I165 PolarHBondContact O-N 3.18Å; I165-W168 PolarHBondContact O-N 2.62Å; I165-A169 VanDerWaalsContact O-CB 3.3Å; I165-A169 WeakPolarHBondContact O-CB 3.44Å; I165-A169 PolarHBondContact O-N 3.11Å
166	G	82.7	Confident	79.1	Confident	12 Å²	12	80.7 Å²	80.7	12%	0.124	38%	0.383	C	S	.	.	H	α-helix	trans	-63.9	-46.4	179.7	0	0	0	0	0	112.8	I162 L164 A169 L170 H234	I162-G166 PolarHBondContact O-N 3.45Å; L164-G166 VanDerWaalsContact C-N 3.33Å; L164-G166 PolarHBondContact O-N 3.3Å; G166-A169 PolarHBondContact O-N 3.26Å; G166-L170 WeakPolarHBondContact O-CG 3.4Å; G166-L170 PolarHBondContact O-N 2.84Å; G166-H234 VanDerWaalsContact CA-NE2 3.27Å; G166-H234 WeakPolarHBondContact CA-NE2 3.49Å; G166-H234 PolarHBondContact O-CE1 2.99Å
167	T	80.8	Confident	77.2	Confident	35 Å²	35	82.2 Å²	82.2	22%	0.215	40%	0.397	C	S	.	.	H	α-helix	trans	-64.9	-44	175	51.3	0	0	0	0	111.4	L163 L164 A169 L170 F171	L163-T167 HydrophobicContact CD2-CG2 4.27Å; L163-T167 HydrophobicContact CG-CG2 4.46Å; L163-T167 WeakPolarHBondContact O-CB 3.47Å; L163-T167 VanDerWaalsContact O-CG2 3.25Å; L163-T167 WeakPolarHBondContact O-CG2 3.35Å; L163-T167 PolarHBondContact O-N 3.09Å; L163-T167 PolarHBondContact O-OG1 2.84Å; L164-T167 PolarHBondContact O-OG1 2.84Å; T167-A169 VanDerWaalsContact C-N 3.32Å; T167-A169 PolarHBondContact O-N 3.32Å; T167-L170 PolarHBondContact O-N 3.01Å; T167-L170 VanDerWaalsContact O-N 3.14Å; T167-F171 WeakPolarHBondContact O-CD2 3.31Å; T167-F171 PolarHBondContact O-N 3.08Å
168	W	82.6	Confident	75.2	Confident	152 Å²	152	81.4 Å²	81.4	58%	0.576	38%	0.384	S	S	*	.	H	α-helix	trans	-56	-45.9	173.6	179.3	81.5	0	0	0	111.9	L164 I165 L170 F171 F172	L164-W168 WeakPolarHBondContact O-CB 3.38Å; L164-W168 PolarHBondContact O-N 3.05Å; I165-W168 PolarHBondContact O-N 2.62Å; W168-L170 VanDerWaalsContact C-N 3.33Å; W168-L170 PolarHBondContact O-N 2.82Å; W168-F171 PolarHBondContact O-N 3.19Å; W168-F172 AromaticContact CD1-CD2 3.16Å; W168-F172 AromaticContact CD1-CE2 3.4Å; W168-F172 AromaticContact CD1-CG 3.93Å; W168-F172 AromaticContact CG-CD2 3.94Å; W168-F172 HydrophobicContact CG-CD2 3.94Å; W168-F172 HydrophobicContact CG-CE2 4.47Å; W168-F172 AromaticContact NE1-CD2 3.29Å; W168-F172 VanDerWaalsContact NE1-CD2 3.29Å; W168-F172 AromaticContact NE1-CE2 3.61Å; W168-F172 AromaticContact NE1-CG 3.58Å; W168-F172 WeakPolarHBondContact O-CB 3.39Å; W168-F172 PolarHBondContact O-N 3.05Å
169	A	76.9	Confident	73.1	Confident	50 Å²	50	79.2 Å²	79.2	41%	0.413	38%	0.377	S	S	.	.	H	α-helix	trans	-62.1	-36.6	177.3	0	0	0	0	0	112.7	I165 G166 T167 R173	I165-A169 VanDerWaalsContact O-CB 3.3Å; I165-A169 WeakPolarHBondContact O-CB 3.44Å; I165-A169 PolarHBondContact O-N 3.11Å; G166-A169 PolarHBondContact O-N 3.26Å; T167-A169 VanDerWaalsContact C-N 3.32Å; T167-A169 PolarHBondContact O-N 3.32Å; A169-R173 VanDerWaalsContact O-CB 3.29Å; A169-R173 WeakPolarHBondContact O-CB 3.46Å
170	L	72.4	Confident	70.9	Confident	52 Å²	52	81.3 Å²	81.3	27%	0.272	39%	0.394	S	S	.	.	H	α-helix	trans	-72.9	-37.5	175.8	-71.6	178.2	0	0	0	113.1	G166 T167 W168 H234 A237 L241	G166-L170 WeakPolarHBondContact O-CG 3.4Å; G166-L170 PolarHBondContact O-N 2.84Å; T167-L170 PolarHBondContact O-N 3.01Å; T167-L170 VanDerWaalsContact O-N 3.14Å; W168-L170 VanDerWaalsContact C-N 3.33Å; W168-L170 PolarHBondContact O-N 2.82Å; L170-H234 WeakPolarHBondContact CD1-CE1 3.39Å; L170-A237 HydrophobicContact CD1-CB 4.43Å; L170-L241 HydrophobicContact CD2-CD1 4.38Å
171	F	66.5	Low	69.1	Low	83 Å²	83	89 Å²	89	36%	0.364	42%	0.423	S	S	.	.	H	α-helix	trans	-84.2	-38	-175.5	-77.4	-68.7	0	0	0	114.1	L113 A116 T167 W168	L113-F171 HydrophobicContact CD1-CD1 4.27Å; A116-F171 HydrophobicContact CB-CE1 3.74Å; A116-F171 HydrophobicContact CB-CZ 3.99Å; T167-F171 WeakPolarHBondContact O-CD2 3.31Å; T167-F171 PolarHBondContact O-N 3.08Å; W168-F171 PolarHBondContact O-N 3.19Å
172	F	61.7	Low	67.5	Low	153 Å²	153	90 Å²	90	67%	0.671	43%	0.433	S	S	*	.	H	α-helix	trans	-87	-4.9	-178.8	-78.9	-94.8	0	0	0	113.9	W168 K174	W168-F172 AromaticContact CD1-CD2 3.16Å; W168-F172 AromaticContact CD1-CE2 3.4Å; W168-F172 AromaticContact CD1-CG 3.93Å; W168-F172 AromaticContact CG-CD2 3.94Å; W168-F172 HydrophobicContact CG-CD2 3.94Å; W168-F172 HydrophobicContact CG-CE2 4.47Å; W168-F172 AromaticContact NE1-CD2 3.29Å; W168-F172 VanDerWaalsContact NE1-CD2 3.29Å; W168-F172 AromaticContact NE1-CE2 3.61Å; W168-F172 AromaticContact NE1-CG 3.58Å; W168-F172 WeakPolarHBondContact O-CB 3.39Å; W168-F172 PolarHBondContact O-N 3.05Å; F172-K174 PolarHBondContact O-N 2.98Å
173	R	62.6	Low	66.2	Low	131 Å²	131	90.8 Å²	90.8	49%	0.494	43%	0.433	S	S	.	.	S	Bend	trans	-71.3	116.7	173.7	-165.5	169.9	-170.8	-173	-0.1	109.8	A169 R175 E242	A169-R173 VanDerWaalsContact O-CB 3.29Å; A169-R173 WeakPolarHBondContact O-CB 3.46Å; R173-R175 PolarHBondContact O-N 2.86Å; R173-E242 IonicContact CZ-OE1 3.56Å; R173-E242 IonicContact CZ-OE2 2.62Å; R173-E242 IonicContact NH1-OE1 3.87Å; R173-E242 PolarHBondContact NH1-OE1 3.37Å; R173-E242 IonicContact NH1-OE2 3.65Å; R173-E242 PolarHBondContact NH1-OE2 3.12Å
174	K	53.9	Low	65.4	Low	195 Å²	195	95.6 Å²	95.6	85%	0.848	46%	0.463	S	S	*	.			trans	-51.8	114.6	175.9	-74.1	-176	178.2	-178.2	0	110.2	F172 R176	F172-K174 PolarHBondContact O-N 2.98Å; K174-R176 PolarHBondContact O-N 3.45Å
175	R	56.4	Low	64.4	Low	125 Å²	125	95.3 Å²	95.3	47%	0.472	46%	0.458	S	S	.	.			trans	-60.7	133.8	170.3	-63.2	179.3	-177.9	-176.1	3.6	107.9	R173 R186 F499	R173-R175 PolarHBondContact O-N 2.86Å; R175-R186 VanDerWaalsContact NE-NH1 3.17Å; R175-F499 WeakPolarHBondContact O-CE2 3.27Å
176	R	51.7	Low	64	Low	80 Å²	80	93.7 Å²	93.7	30%	0.302	45%	0.445	S	S	.	.	S	Bend	trans	-95.2	-11.5	-175	-71.9	-173.7	-177	177.9	5.5	115.2	K174 V249 H269 F499	K174-R176 PolarHBondContact O-N 3.45Å; R176-V249 VanDerWaalsContact CZ-CG2 3.49Å; R176-V249 VanDerWaalsContact NH1-CA 3.3Å; R176-V249 VanDerWaalsContact NH1-CB 3.31Å; R176-H269 PolarHBondContact NH2-CD2 3.23Å; R176-H269 PolarHBondContact NH2-NE2 2.88Å; R176-F499 WeakPolarHBondContact O-CD2 3.45Å; R176-F499 VanDerWaalsContact O-CE2 3.24Å; R176-F499 WeakPolarHBondContact O-CE2 3.46Å
177	A	52.6	Low	63.8	Low	40 Å²	40	94.7 Å²	94.7	33%	0.331	45%	0.453	S	S	.	.	S	Bend	trans	-147.8	126.1	167.6	0	0	0	0	0	105.9
178	D	49.2	Very low	63.9	Low	44 Å²	44	97.6 Å²	97.6	24%	0.235	47%	0.466	C	S	.	.			trans	-88.5	118.2	166.9	-83.7	-19.6	0	0	0	106.6	R109 F499	R109-D178 IonicContact CZ-OD2 3.84Å; R109-D178 IonicContact NE-OD2 3.92Å; R109-D178 IonicContact NH2-OD2 3.92Å; R109-D178 PolarHBondContact NH2-OD2 3.27Å; D178-F499 HydrophobicContact CB-CZ 4.37Å
179	M	49.6	Very low	64	Low	88 Å²	88	90.8 Å²	90.8	43%	0.433	44%	0.441	S	S	.	.			trans	-102.8	139.5	171	-67.8	-109.7	132.2	0	0	107.2	R181 F183 L502	M179-R181 PolarHBondContact O-N 2.9Å; M179-F183 HydrophobicContact CB-CZ 4.46Å; M179-F183 HydrophobicContact CG-CZ 4.38Å; M179-L502 HydrophobicContact CE-CB 4.19Å; M179-L502 HydrophobicContact CE-CD2 3.78Å
180	P	47.4	Very low	64.5	Low	86 Å²	86	90.8 Å²	90.8	56%	0.558	43%	0.434	S	S	*	.	S	Bend	trans	-65.6	-18.9	-177.5	24.5	-32.5	0	0	0	113	E504	P180-E504 HydrophobicContact CG-CG 4.21Å
181	R	55	Low	65.3	Low	175 Å²	175	92.3 Å²	92.3	66%	0.66	45%	0.445	S	S	*	.	S	Bend	trans	-90	138.6	-178.7	-58.1	-174.7	-169.5	-159.1	-0.9	112.3	M179 F183 E504	M179-R181 PolarHBondContact O-N 2.9Å; R181-F183 PolarHBondContact O-N 2.96Å; R181-E504 IonicContact CZ-OE2 2.65Å; R181-E504 IonicContact NE-OE1 3.06Å; R181-E504 IonicContact NE-OE2 3.01Å; R181-E504 PolarHBondContact NE-OE2 3.03Å; R181-E504 VanDerWaalsContact NE-OE2 3.08Å; R181-E504 IonicContact NH2-OE2 2.74Å; R181-E504 PolarHBondContact NH2-OE2 3.37Å
182	V	58.1	Low	66.5	Low	115 Å²	115	90.7 Å²	90.7	70%	0.697	44%	0.44	S	S	*	.			trans	-60	120	170.1	-174.2	0	0	0	0	108.6	V184 A187	V182-V184 PolarHBondContact O-N 3.35Å; V182-A187 HydrophobicContact CG1-CB 3.85Å
183	F	64.1	Low	67.8	Low	92 Å²	92	85.2 Å²	85.2	40%	0.404	42%	0.417	S	S	.	.			trans	-58.8	114.4	174.6	-76.4	-87.2	0	0	0	109.4	M179 R181 F185 R186 A187	M179-F183 HydrophobicContact CB-CZ 4.46Å; M179-F183 HydrophobicContact CG-CZ 4.38Å; R181-F183 PolarHBondContact O-N 2.96Å; F183-F185 PolarHBondContact O-N 3.41Å; F183-F185 VanDerWaalsContact O-N 3.12Å; F183-R186 HydrophobicContact CB-CB 4.11Å; F183-R186 HydrophobicContact CB-CG 4.03Å; F183-R186 WeakPolarHBondContact O-CA 3.45Å; F183-R186 WeakPolarHBondContact O-CB 3.32Å; F183-R186 PolarHBondContact O-N 2.95Å; F183-A187 PolarHBondContact O-N 3.35Å
184	V	71.5	Confident	69.3	Low	110 Å²	110	84.2 Å²	84.2	67%	0.667	42%	0.417	S	S	*	.	H	α-helix	trans	-51.4	-40.7	-175.6	-179.4	0	0	0	0	112.1	V182 R186 A187 L188	V182-V184 PolarHBondContact O-N 3.35Å; V184-R186 PolarHBondContact O-N 3.42Å; V184-A187 PolarHBondContact O-N 3.34Å; V184-L188 VanDerWaalsContact O-CB 3.27Å; V184-L188 WeakPolarHBondContact O-CB 3.43Å; V184-L188 PolarHBondContact O-N 3.38Å
185	F	70.1	Confident	71.1	Confident	85 Å²	85	79.7 Å²	79.7	37%	0.373	40%	0.401	S	S	.	.	H	α-helix	trans	-65.8	-37.3	176.7	-63.3	-76.7	0	0	0	113.3	F183 L189	F183-F185 PolarHBondContact O-N 3.41Å; F183-F185 VanDerWaalsContact O-N 3.12Å; F185-L189 WeakPolarHBondContact O-CB 3.32Å; F185-L189 WeakPolarHBondContact O-CD1 3.47Å; F185-L189 WeakPolarHBondContact O-CG 3.33Å; F185-L189 PolarHBondContact O-N 2.94Å
186	R	77.4	Confident	72.8	Confident	64 Å²	64	77.2 Å²	77.2	24%	0.242	39%	0.394	C	S	.	.	H	α-helix	trans	-69.6	-41.6	175.4	-70.8	-175	175.5	163.9	-2.5	111.1	R175 F183 V184 L189 L190 L241	R175-R186 VanDerWaalsContact NE-NH1 3.17Å; F183-R186 HydrophobicContact CB-CB 4.11Å; F183-R186 HydrophobicContact CB-CG 4.03Å; F183-R186 WeakPolarHBondContact O-CA 3.45Å; F183-R186 WeakPolarHBondContact O-CB 3.32Å; F183-R186 PolarHBondContact O-N 2.95Å; V184-R186 PolarHBondContact O-N 3.42Å; R186-L189 PolarHBondContact O-N 3.47Å; R186-L190 VanDerWaalsContact O-CG 3.3Å; R186-L190 WeakPolarHBondContact O-CG 3.28Å; R186-L190 PolarHBondContact O-N 3.42Å; R186-L241 HydrophobicContact CG-CD2 4.12Å
187	A	79.8	Confident	74.8	Confident	34 Å²	34	73.6 Å²	73.6	28%	0.281	38%	0.381	S	S	.	.	H	α-helix	trans	-60.5	-46.7	173.6	0	0	0	0	0	111.1	V182 F183 V184 L189 L190 V191	V182-A187 HydrophobicContact CG1-CB 3.85Å; F183-A187 PolarHBondContact O-N 3.35Å; V184-A187 PolarHBondContact O-N 3.34Å; A187-L189 PolarHBondContact O-N 2.95Å; A187-L190 PolarHBondContact O-N 3.15Å; A187-V191 VanDerWaalsContact O-CG2 3.32Å; A187-V191 WeakPolarHBondContact O-CG2 3.41Å; A187-V191 PolarHBondContact O-N 2.92Å
188	L	83.3	Confident	76.7	Confident	95 Å²	95	74.5 Å²	74.5	50%	0.497	38%	0.382	S	S	.	.	H	α-helix	trans	-59.8	-44.9	177.3	-174.7	155.1	0	0	0	111.7	V184 V191 L192	V184-L188 VanDerWaalsContact O-CB 3.27Å; V184-L188 WeakPolarHBondContact O-CB 3.43Å; V184-L188 PolarHBondContact O-N 3.38Å; L188-V191 PolarHBondContact O-N 3.44Å; L188-L192 WeakPolarHBondContact O-CB 3.48Å; L188-L192 PolarHBondContact O-N 3.44Å
189	L	84.4	Confident	78.8	Confident	10 Å²	10	75.2 Å²	75.2	5%	0.052	39%	0.391	C	S	.	.	H	α-helix	trans	-63.6	-40.7	176.7	-72.8	166.9	0	0	0	112.2	F185 R186 A187 L192 I193 I233 A237 L241	F185-L189 WeakPolarHBondContact O-CB 3.32Å; F185-L189 WeakPolarHBondContact O-CD1 3.47Å; F185-L189 WeakPolarHBondContact O-CG 3.33Å; F185-L189 PolarHBondContact O-N 2.94Å; R186-L189 PolarHBondContact O-N 3.47Å; A187-L189 PolarHBondContact O-N 2.95Å; L189-L192 PolarHBondContact O-N 2.96Å; L189-I193 VanDerWaalsContact O-CG1 3.28Å; L189-I193 WeakPolarHBondContact O-CG1 3.3Å; L189-I193 PolarHBondContact O-N 2.99Å; L189-I233 HydrophobicContact CD2-CG2 4.25Å; L189-A237 HydrophobicContact CD1-CB 3.62Å; L189-A237 HydrophobicContact CD2-CB 4.18Å; L189-L241 HydrophobicContact CD1-CD1 4.48Å
190	L	86.3	Confident	81	Confident	50 Å²	50	73 Å²	73	26%	0.262	38%	0.378	S	S	.	.	H	α-helix	trans	-65.3	-43	175.9	-71.1	172.3	0	0	0	111.6	A116 L119 R186 A187 L192 I193 F194	A116-L190 HydrophobicContact CB-CD1 3.93Å; A116-L190 HydrophobicContact CB-CD2 3.84Å; L119-L190 HydrophobicContact CD2-CB 4.31Å; L119-L190 HydrophobicContact CD2-CD2 4.09Å; L119-L190 VanDerWaalsContact CD2-O 3.22Å; L119-L190 WeakPolarHBondContact CD2-O 3.09Å; R186-L190 VanDerWaalsContact O-CG 3.3Å; R186-L190 WeakPolarHBondContact O-CG 3.28Å; R186-L190 PolarHBondContact O-N 3.42Å; A187-L190 PolarHBondContact O-N 3.15Å; L190-L192 VanDerWaalsContact C-N 3.32Å; L190-L192 PolarHBondContact O-N 3.37Å; L190-I193 PolarHBondContact O-N 3.24Å; L190-F194 WeakPolarHBondContact O-CB 3.26Å; L190-F194 PolarHBondContact O-N 3.02Å
191	V	89.6	Confident	83.2	Confident	84 Å²	84	73.2 Å²	73.2	51%	0.509	37%	0.368	S	S	.	.	H	α-helix	trans	-61.2	-43	174.2	171	0	0	0	0	110.6	A187 L188 F194 L195	A187-V191 VanDerWaalsContact O-CG2 3.32Å; A187-V191 WeakPolarHBondContact O-CG2 3.41Å; A187-V191 PolarHBondContact O-N 2.92Å; L188-V191 PolarHBondContact O-N 3.44Å; V191-F194 PolarHBondContact O-N 2.98Å; V191-L195 HydrophobicContact CG1-CD1 4.01Å; V191-L195 HydrophobicContact CG1-CG 4.29Å; V191-L195 WeakPolarHBondContact O-CG 3.48Å; V191-L195 PolarHBondContact O-N 3.31Å
192	L	90.9	Very high	85	Confident	48 Å²	48	70.6 Å²	70.6	25%	0.251	37%	0.366	S	S	.	.	H	α-helix	trans	-61	-47.7	177.5	-171.3	68.6	0	0	0	111.6	L188 L189 L190 F194 L195 F196 I233	L188-L192 WeakPolarHBondContact O-CB 3.48Å; L188-L192 PolarHBondContact O-N 3.44Å; L189-L192 PolarHBondContact O-N 2.96Å; L190-L192 VanDerWaalsContact C-N 3.32Å; L190-L192 PolarHBondContact O-N 3.37Å; L192-F194 VanDerWaalsContact C-N 3.31Å; L192-F194 PolarHBondContact O-N 2.88Å; L192-L195 PolarHBondContact O-N 3.5Å; L192-F196 HydrophobicContact CD1-CD2 3.94Å; L192-F196 HydrophobicContact CD1-CE2 3.66Å; L192-F196 HydrophobicContact CG-CD2 4.11Å; L192-F196 HydrophobicContact CG-CE2 4.14Å; L192-F196 WeakPolarHBondContact O-CD2 3.15Å; L192-F196 PolarHBondContact O-N 3.28Å; L192-I233 HydrophobicContact CD2-CD1 4.18Å; L192-I233 HydrophobicContact CD2-CG1 3.9Å; L192-I233 HydrophobicContact CD2-CG2 4.16Å; L192-I233 HydrophobicContact CG-CD1 4.09Å; L192-I233 HydrophobicContact CG-CG1 4.38Å
193	I	90.9	Very high	86.6	Confident	38 Å²	38	69.5 Å²	69.5	20%	0.195	35%	0.352	C	S	.	.	H	α-helix	trans	-58.4	-46	175.9	-67.9	166	0	0	0	110.3	L119 A123 L189 L190 F196 V197 L230 I233	L119-I193 HydrophobicContact CD2-CB 4.19Å; L119-I193 HydrophobicContact CD2-CG2 4.06Å; L119-I193 HydrophobicContact CG-CG2 4Å; A123-I193 HydrophobicContact CB-CG2 4.05Å; L189-I193 VanDerWaalsContact O-CG1 3.28Å; L189-I193 WeakPolarHBondContact O-CG1 3.3Å; L189-I193 PolarHBondContact O-N 2.99Å; L190-I193 PolarHBondContact O-N 3.24Å; I193-F196 PolarHBondContact O-N 3.42Å; I193-V197 HydrophobicContact CG2-CG2 4.23Å; I193-V197 WeakPolarHBondContact O-CB 3.32Å; I193-V197 VanDerWaalsContact O-CG2 3.26Å; I193-V197 WeakPolarHBondContact O-CG2 3.37Å; I193-V197 PolarHBondContact O-N 3.06Å; I193-L230 HydrophobicContact CG2-CD2 4.42Å; I193-I233 HydrophobicContact CD1-CG2 4.29Å; I193-I233 HydrophobicContact CG1-CG2 3.76Å
194	F	92.2	Very high	88	Confident	111 Å²	111	65.1 Å²	65.1	49%	0.487	33%	0.333	S	S	.	.	H	α-helix	trans	-59.8	-49	178.9	176.1	-100	0	0	0	112.2	L119 L190 V191 L192 F196 V197 V198	L119-F194 HydrophobicContact CD1-CB 4.09Å; L119-F194 HydrophobicContact CD1-CD2 3.99Å; L119-F194 HydrophobicContact CD2-CB 4.03Å; L190-F194 WeakPolarHBondContact O-CB 3.26Å; L190-F194 PolarHBondContact O-N 3.02Å; V191-F194 PolarHBondContact O-N 2.98Å; L192-F194 VanDerWaalsContact C-N 3.31Å; L192-F194 PolarHBondContact O-N 2.88Å; F194-F196 PolarHBondContact O-N 3.36Å; F194-V197 PolarHBondContact O-N 3.37Å; F194-V198 HydrophobicContact CD1-CG2 4.47Å; F194-V198 HydrophobicContact CD2-CG2 4.13Å; F194-V198 HydrophobicContact CE1-CG2 4.11Å; F194-V198 HydrophobicContact CE2-CG2 3.74Å; F194-V198 HydrophobicContact CG-CG2 4.48Å; F194-V198 HydrophobicContact CZ-CG2 3.74Å; F194-V198 WeakPolarHBondContact O-CB 3.43Å; F194-V198 WeakPolarHBondContact O-CG2 3.46Å; F194-V198 PolarHBondContact O-N 2.86Å
195	L	92.9	Very high	88.9	Confident	99 Å²	99	61 Å²	61	52%	0.518	31%	0.313	S	S	.	.	H	α-helix	trans	-59.8	-45.4	179.4	-71.1	176.9	0	0	0	111.9	V191 L192 S199	V191-L195 HydrophobicContact CG1-CD1 4.01Å; V191-L195 HydrophobicContact CG1-CG 4.29Å; V191-L195 WeakPolarHBondContact O-CG 3.48Å; V191-L195 PolarHBondContact O-N 3.31Å; L192-L195 PolarHBondContact O-N 3.5Å; L195-S199 WeakPolarHBondContact O-CB 3.44Å; L195-S199 PolarHBondContact O-N 3.14Å; L195-S199 PolarHBondContact O-OG 2.82Å
196	F	92.1	Very high	89.9	Confident	73 Å²	73	62 Å²	62	32%	0.32	33%	0.325	S	S	.	.	H	α-helix	trans	-62.8	-48.4	177.5	-91.8	-99.4	0	0	0	111.7	L192 I193 F194 V198 S199 Y200 A229 I233	L192-F196 HydrophobicContact CD1-CD2 3.94Å; L192-F196 HydrophobicContact CD1-CE2 3.66Å; L192-F196 HydrophobicContact CG-CD2 4.11Å; L192-F196 HydrophobicContact CG-CE2 4.14Å; L192-F196 WeakPolarHBondContact O-CD2 3.15Å; L192-F196 PolarHBondContact O-N 3.28Å; I193-F196 PolarHBondContact O-N 3.42Å; F194-F196 PolarHBondContact O-N 3.36Å; F196-V198 VanDerWaalsContact C-N 3.35Å; F196-V198 PolarHBondContact O-N 3.09Å; F196-S199 WeakPolarHBondContact CA-OG 3.24Å; F196-S199 PolarHBondContact O-N 2.85Å; F196-S199 PolarHBondContact O-OG 2.85Å; F196-Y200 HydrophobicContact CD1-CD2 4.46Å; F196-Y200 AromaticContact CD1-CE2 3.97Å; F196-Y200 HydrophobicContact CD1-CE2 3.97Å; F196-Y200 WeakPolarHBondContact O-CB 3.48Å; F196-Y200 VanDerWaalsContact O-CD2 3.24Å; F196-Y200 WeakPolarHBondContact O-CD2 3.2Å; F196-Y200 PolarHBondContact O-N 2.72Å; F196-A229 HydrophobicContact CD1-CB 4.1Å; F196-A229 HydrophobicContact CE1-CB 4.18Å; F196-I233 HydrophobicContact CB-CD1 4.39Å; F196-I233 HydrophobicContact CD1-CD1 4.48Å; F196-I233 HydrophobicContact CD2-CD1 3.96Å; F196-I233 HydrophobicContact CE2-CD1 4.37Å; F196-I233 HydrophobicContact CG-CD1 4.01Å
197	V	92.4	Very high	90.3	Very high	4 Å²	4	65.5 Å²	65.5	2%	0.024	34%	0.339	C	S	.	.	H	α-helix	trans	-62.8	-43.8	-178.3	174.6	0	0	0	0	111.1	L122 A123 T126 I193 F194 Y200 W201 L230	L122-V197 HydrophobicContact CD2-CG1 3.35Å; A123-V197 HydrophobicContact CB-CG2 4.07Å; T126-V197 HydrophobicContact CG2-CG1 3.94Å; I193-V197 HydrophobicContact CG2-CG2 4.23Å; I193-V197 WeakPolarHBondContact O-CB 3.32Å; I193-V197 VanDerWaalsContact O-CG2 3.26Å; I193-V197 WeakPolarHBondContact O-CG2 3.37Å; I193-V197 PolarHBondContact O-N 3.06Å; F194-V197 PolarHBondContact O-N 3.37Å; V197-Y200 PolarHBondContact O-N 3.25Å; V197-W201 VanDerWaalsContact O-CD1 3.32Å; V197-W201 PolarHBondContact O-N 2.92Å; V197-L230 HydrophobicContact CG2-CD2 4.26Å
198	V	93.6	Very high	90.7	Very high	59 Å²	59	64.1 Å²	64.1	36%	0.358	33%	0.326	S	S	.	.	H	α-helix	trans	-64.2	-44.7	176.8	172.9	0	0	0	0	111.5	F194 F196 Y200 W201 L202	F194-V198 HydrophobicContact CD1-CG2 4.47Å; F194-V198 HydrophobicContact CD2-CG2 4.13Å; F194-V198 HydrophobicContact CE1-CG2 4.11Å; F194-V198 HydrophobicContact CE2-CG2 3.74Å; F194-V198 HydrophobicContact CG-CG2 4.48Å; F194-V198 HydrophobicContact CZ-CG2 3.74Å; F194-V198 WeakPolarHBondContact O-CB 3.43Å; F194-V198 WeakPolarHBondContact O-CG2 3.46Å; F194-V198 PolarHBondContact O-N 2.86Å; F196-V198 VanDerWaalsContact C-N 3.35Å; F196-V198 PolarHBondContact O-N 3.09Å; V198-Y200 VanDerWaalsContact C-N 3.3Å; V198-Y200 PolarHBondContact O-N 2.88Å; V198-W201 PolarHBondContact O-N 2.51Å; V198-L202 HydrophobicContact CG1-CD1 4.13Å; V198-L202 HydrophobicContact CG1-CG 4.41Å; V198-L202 WeakPolarHBondContact O-CG 3.48Å; V198-L202 PolarHBondContact O-N 2.76Å
199	S	93.8	Very high	90.8	Very high	59 Å²	59	62 Å²	62	41%	0.413	32%	0.315	S	S	.	.	H	α-helix	trans	-62.1	-39	179.5	63.9	0	0	0	0	112.4	L195 F196 F203	L195-S199 WeakPolarHBondContact O-CB 3.44Å; L195-S199 PolarHBondContact O-N 3.14Å; L195-S199 PolarHBondContact O-OG 2.82Å; F196-S199 WeakPolarHBondContact CA-OG 3.24Å; F196-S199 PolarHBondContact O-N 2.85Å; F196-S199 PolarHBondContact O-OG 2.85Å; S199-F203 PolarHBondContact O-N 3.37Å; S199-F203 VanDerWaalsContact O-N 3.14Å
200	Y	94.3	Very high	91	Very high	42 Å²	42	67.9 Å²	67.9	17%	0.165	35%	0.347	C	S	.	.	H	α-helix	trans	-69.8	-37.8	177.4	-89.8	-100.3	0	0	0	112	F196 V197 V198 Y204 Y222 L226	F196-Y200 HydrophobicContact CD1-CD2 4.46Å; F196-Y200 AromaticContact CD1-CE2 3.97Å; F196-Y200 HydrophobicContact CD1-CE2 3.97Å; F196-Y200 WeakPolarHBondContact O-CB 3.48Å; F196-Y200 VanDerWaalsContact O-CD2 3.24Å; F196-Y200 WeakPolarHBondContact O-CD2 3.2Å; F196-Y200 PolarHBondContact O-N 2.72Å; V197-Y200 PolarHBondContact O-N 3.25Å; V198-Y200 VanDerWaalsContact C-N 3.3Å; V198-Y200 PolarHBondContact O-N 2.88Å; Y200-Y204 WeakPolarHBondContact O-CB 3.22Å; Y200-Y204 PolarHBondContact O-N 3.15Å; Y200-Y222 WeakPolarHBondContact CA-OH 3.31Å; Y200-Y222 AromaticContact CD1-CE1 3.81Å; Y200-Y222 HydrophobicContact CD1-CE1 3.81Å; Y200-Y222 AromaticContact CD1-CE2 3.95Å; Y200-Y222 HydrophobicContact CD1-CE2 3.95Å; Y200-Y222 AromaticContact CD1-CZ 3.37Å; Y200-Y222 WeakPolarHBondContact CD1-OH 3.37Å; Y200-Y222 HydrophobicContact CE1-CE1 4.46Å; Y200-Y222 AromaticContact CE1-CE2 3.9Å; Y200-Y222 HydrophobicContact CE1-CE2 3.9Å; Y200-Y222 AromaticContact CE1-CZ 3.83Å; Y200-Y222 PolarHBondContact O-OH 2.64Å; Y200-L226 HydrophobicContact CD1-CB 3.76Å; Y200-L226 HydrophobicContact CD1-CD1 3.98Å; Y200-L226 HydrophobicContact CD1-CG 4.31Å; Y200-L226 HydrophobicContact CD2-CD1 3.93Å; Y200-L226 HydrophobicContact CE1-CB 3.82Å; Y200-L226 HydrophobicContact CE1-CD1 4.4Å; Y200-L226 HydrophobicContact CE2-CD1 4.34Å; Y200-L226 HydrophobicContact CG-CB 4.4Å; Y200-L226 HydrophobicContact CG-CD1 3.73Å; Y200-L226 HydrophobicContact CG-CG 4.48Å
201	W	94.4	Very high	90.9	Very high	91 Å²	91	69.1 Å²	69.1	35%	0.345	36%	0.359	S	S	.	.	H	α-helix	trans	-62.9	-44	172.9	-94.5	104.8	0	0	0	113.2	T126 A129 F130 L133 V197 V198 F203 Y204 G205	T126-W201 HydrophobicContact CG2-CZ2 4.16Å; A129-W201 HydrophobicContact CB-CZ2 4.43Å; F130-W201 AromaticContact CE1-CD2 3.69Å; F130-W201 HydrophobicContact CE1-CD2 3.69Å; F130-W201 AromaticContact CE1-CE2 3.73Å; F130-W201 AromaticContact CE1-CE3 3.85Å; F130-W201 HydrophobicContact CE1-CE3 3.85Å; F130-W201 HydrophobicContact CE1-CG 4.24Å; F130-W201 HydrophobicContact CE1-CH2 4.1Å; F130-W201 AromaticContact CE1-CZ2 3.95Å; F130-W201 HydrophobicContact CE1-CZ2 3.95Å; F130-W201 HydrophobicContact CE1-CZ3 4.05Å; F130-W201 HydrophobicContact CZ-CD2 4.13Å; F130-W201 HydrophobicContact CZ-CG 4.19Å; L133-W201 HydrophobicContact CD1-CH2 4.27Å; V197-W201 VanDerWaalsContact O-CD1 3.32Å; V197-W201 PolarHBondContact O-N 2.92Å; V198-W201 PolarHBondContact O-N 2.51Å; W201-F203 VanDerWaalsContact C-N 3.35Å; W201-F203 PolarHBondContact O-N 3.17Å; W201-Y204 PolarHBondContact O-N 3.44Å; W201-G205 PolarHBondContact O-N 3.32Å
202	L	92.9	Very high	90.5	Very high	119 Å²	119	71.9 Å²	71.9	62%	0.623	36%	0.361	S	S	*	.	H	α-helix	trans	-61.6	-46.2	178.8	-71.6	174.6	0	0	0	111	V198 G205 V206	V198-L202 HydrophobicContact CG1-CD1 4.13Å; V198-L202 HydrophobicContact CG1-CG 4.41Å; V198-L202 WeakPolarHBondContact O-CG 3.48Å; V198-L202 PolarHBondContact O-N 2.76Å; L202-G205 PolarHBondContact O-N 3.43Å; L202-V206 WeakPolarHBondContact O-CG2 3.43Å; L202-V206 PolarHBondContact O-N 3.2Å
203	F	92.6	Very high	90.1	Very high	93 Å²	93	71.9 Å²	71.9	41%	0.408	36%	0.361	S	S	.	.	H	α-helix	trans	-68.2	-38.4	178.3	-170.8	-94.4	0	0	0	112.2	S199 W201 R207 Y222	S199-F203 PolarHBondContact O-N 3.37Å; S199-F203 VanDerWaalsContact O-N 3.14Å; W201-F203 VanDerWaalsContact C-N 3.35Å; W201-F203 PolarHBondContact O-N 3.17Å; F203-R207 HydrophobicContact CD1-CB 4.27Å; F203-R207 HydrophobicContact CE1-CB 4.16Å; F203-R207 HydrophobicContact CE1-CG 4.33Å; F203-R207 HydrophobicContact CZ-CB 4.39Å; F203-R207 HydrophobicContact CZ-CG 4.41Å; F203-R207 WeakPolarHBondContact O-CB 3.44Å; F203-R207 PolarHBondContact O-N 3.47Å; F203-Y222 WeakPolarHBondContact CB-OH 3.39Å; F203-Y222 HydrophobicContact CD1-CD2 4.5Å; F203-Y222 HydrophobicContact CD1-CE1 4.36Å; F203-Y222 AromaticContact CD1-CE2 3.58Å; F203-Y222 HydrophobicContact CD1-CE2 3.58Å; F203-Y222 AromaticContact CD1-CZ 3.5Å; F203-Y222 VanDerWaalsContact CD1-CZ 3.5Å; F203-Y222 VanDerWaalsContact CD1-OH 3.3Å; F203-Y222 WeakPolarHBondContact CD1-OH 3.48Å; F203-Y222 HydrophobicContact CE1-CD2 4.42Å; F203-Y222 AromaticContact CE1-CE2 3.79Å; F203-Y222 HydrophobicContact CE1-CE2 3.79Å
204	Y	92.2	Very high	89.8	Confident	0 Å²	0	76.5 Å²	76.5	0%	0	38%	0.376	C	S	.	.	H	α-helix	trans	-61.4	-44.7	173	-173.6	-90.4	0	0	0	111.8	F130 P134 Y200 W201 I208 L209 I219 Y222	F130-Y204 HydrophobicContact CB-CD2 4.15Å; F130-Y204 HydrophobicContact CB-CE2 3.66Å; F130-Y204 AromaticContact CD1-CD1 3.92Å; F130-Y204 HydrophobicContact CD1-CD1 3.92Å; F130-Y204 AromaticContact CD1-CD2 3.75Å; F130-Y204 HydrophobicContact CD1-CD2 3.75Å; F130-Y204 AromaticContact CD1-CE1 4Å; F130-Y204 HydrophobicContact CD1-CE1 4Å; F130-Y204 AromaticContact CD1-CE2 3.84Å; F130-Y204 HydrophobicContact CD1-CE2 3.84Å; F130-Y204 AromaticContact CD1-CG 3.8Å; F130-Y204 HydrophobicContact CD1-CG 3.8Å; F130-Y204 AromaticContact CD1-CZ 3.96Å; F130-Y204 AromaticContact CD2-CD2 3.68Å; F130-Y204 HydrophobicContact CD2-CD2 3.68Å; F130-Y204 HydrophobicContact CD2-CE2 4.09Å; F130-Y204 HydrophobicContact CD2-CG 4.25Å; F130-Y204 AromaticContact CE1-CD1 3.83Å; F130-Y204 HydrophobicContact CE1-CD1 3.83Å; F130-Y204 AromaticContact CE1-CD2 3.99Å; F130-Y204 HydrophobicContact CE1-CD2 3.99Å; F130-Y204 HydrophobicContact CE1-CE1 4.35Å; F130-Y204 HydrophobicContact CE1-CE2 4.5Å; F130-Y204 AromaticContact CE1-CG 3.63Å; F130-Y204 HydrophobicContact CE1-CG 3.63Å; F130-Y204 AromaticContact CE2-CD2 3.92Å; F130-Y204 HydrophobicContact CE2-CD2 3.92Å; F130-Y204 HydrophobicContact CE2-CG 4.1Å; F130-Y204 AromaticContact CG-CD2 3.59Å; F130-Y204 HydrophobicContact CG-CD2 3.59Å; F130-Y204 AromaticContact CG-CE2 3.61Å; F130-Y204 HydrophobicContact CG-CE2 3.61Å; F130-Y204 HydrophobicContact CG-CG 4.12Å; F130-Y204 HydrophobicContact CZ-CD1 4.42Å; F130-Y204 HydrophobicContact CZ-CD2 4.08Å; F130-Y204 AromaticContact CZ-CG 3.8Å; F130-Y204 HydrophobicContact CZ-CG 3.8Å; F130-Y204 PolarHBondContact O-OH 3.26Å; P134-Y204 VanDerWaalsContact CD-OH 3.25Å; P134-Y204 WeakPolarHBondContact CD-OH 3.48Å; P134-Y204 VanDerWaalsContact CG-OH 3.3Å; P134-Y204 WeakPolarHBondContact CG-OH 3.45Å; Y200-Y204 WeakPolarHBondContact O-CB 3.22Å; Y200-Y204 PolarHBondContact O-N 3.15Å; W201-Y204 PolarHBondContact O-N 3.44Å; Y204-I208 HydrophobicContact CD2-CB 4.24Å; Y204-I208 HydrophobicContact CD2-CD1 3.34Å; Y204-I208 HydrophobicContact CD2-CG1 4.36Å; Y204-I208 HydrophobicContact CD2-CG2 4.48Å; Y204-I208 HydrophobicContact CE2-CB 4.25Å; Y204-I208 HydrophobicContact CE2-CD1 3.68Å; Y204-I208 HydrophobicContact CE2-CG2 3.99Å; Y204-I208 HydrophobicContact CG-CB 4.49Å; Y204-I208 HydrophobicContact CG-CD1 4.15Å; Y204-I208 WeakPolarHBondContact O-CA 3.41Å; Y204-I208 VanDerWaalsContact O-CB 3.32Å; Y204-I208 WeakPolarHBondContact O-CB 3.27Å; Y204-I208 PolarHBondContact O-N 3.32Å; Y204-L209 HydrophobicContact CD1-CD1 3.91Å; Y204-L209 HydrophobicContact CD1-CG 3.91Å; Y204-L209 HydrophobicContact CE1-CD1 3.84Å; Y204-L209 HydrophobicContact CE1-CD2 3.87Å; Y204-L209 HydrophobicContact CE1-CG 3.65Å; Y204-L209 PolarHBondContact O-N 2.93Å; Y204-L209 VanDerWaalsContact O-N 3.09Å; Y204-I219 HydrophobicContact CE2-CG2 4.05Å; Y204-Y222 HydrophobicContact CD2-CD1 4.08Å; Y204-Y222 HydrophobicContact CD2-CE1 4.16Å
205	G	89.8	Confident	89.6	Confident	24 Å²	24	74.6 Å²	74.6	25%	0.247	37%	0.371	C	S	.	.	I	π-helix	trans	-58.7	-53.2	177.9	0	0	0	0	0	112.4	W201 L202 L209 D210	W201-G205 PolarHBondContact O-N 3.32Å; L202-G205 PolarHBondContact O-N 3.43Å; G205-L209 WeakPolarHBondContact O-CB 3.37Å; G205-L209 PolarHBondContact O-N 2.97Å; G205-D210 PolarHBondContact O-N 3.25Å
206	V	91.6	Very high	89.3	Confident	104 Å²	104	71.3 Å²	71.3	63%	0.63	35%	0.352	S	S	*	.	I	π-helix	trans	-72.9	-46.8	-177.4	178.1	0	0	0	0	111.8	L202 D210	L202-V206 WeakPolarHBondContact O-CG2 3.43Å; L202-V206 PolarHBondContact O-N 3.2Å; V206-D210 WeakPolarHBondContact O-CB 3.31Å
207	R	87	Confident	89.1	Confident	139 Å²	139	71 Å²	71	53%	0.525	35%	0.351	S	S	.	.	I	π-helix	trans	-82.5	-30.9	-171.1	-171.2	-178.9	175	-172.2	0.6	113.3	F203 S211	F203-R207 HydrophobicContact CD1-CB 4.27Å; F203-R207 HydrophobicContact CE1-CB 4.16Å; F203-R207 HydrophobicContact CE1-CG 4.33Å; F203-R207 HydrophobicContact CZ-CB 4.39Å; F203-R207 HydrophobicContact CZ-CG 4.41Å; F203-R207 WeakPolarHBondContact O-CB 3.44Å; F203-R207 PolarHBondContact O-N 3.47Å; R207-S211 WeakPolarHBondContact O-CB 3.42Å; R207-S211 PolarHBondContact O-OG 3.1Å
208	I	87.2	Confident	89	Confident	5 Å²	5	72 Å²	72	3%	0.026	36%	0.363	C	S	.	.	I	π-helix	trans	-111.8	-46.1	-171.7	-63.2	159.6	0	0	0	110.9	Y204 R212 D213 I219 Y222	Y204-I208 HydrophobicContact CD2-CB 4.24Å; Y204-I208 HydrophobicContact CD2-CD1 3.34Å; Y204-I208 HydrophobicContact CD2-CG1 4.36Å; Y204-I208 HydrophobicContact CD2-CG2 4.48Å; Y204-I208 HydrophobicContact CE2-CB 4.25Å; Y204-I208 HydrophobicContact CE2-CD1 3.68Å; Y204-I208 HydrophobicContact CE2-CG2 3.99Å; Y204-I208 HydrophobicContact CG-CB 4.49Å; Y204-I208 HydrophobicContact CG-CD1 4.15Å; Y204-I208 WeakPolarHBondContact O-CA 3.41Å; Y204-I208 VanDerWaalsContact O-CB 3.32Å; Y204-I208 WeakPolarHBondContact O-CB 3.27Å; Y204-I208 PolarHBondContact O-N 3.32Å; I208-R212 WeakPolarHBondContact O-CA 3.08Å; I208-R212 PolarHBondContact O-N 3.28Å; I208-D213 PolarHBondContact O-N 3.21Å; I208-I219 HydrophobicContact CD1-CG1 4.45Å; I208-I219 HydrophobicContact CG1-CG1 4.45Å; I208-I219 HydrophobicContact CG2-CD1 3.74Å; I208-I219 HydrophobicContact CG2-CG1 3.89Å; I208-I219 HydrophobicContact CG2-CG2 4.48Å; I208-Y222 HydrophobicContact CD1-CD1 3.91Å; I208-Y222 HydrophobicContact CD1-CE1 4.44Å; I208-Y222 HydrophobicContact CD1-CG 4.36Å
209	L	86.4	Confident	88.8	Confident	49 Å²	49	69.2 Å²	69.2	26%	0.257	35%	0.346	S	S	.	.	I	π-helix	trans	-77.2	-45.2	-178.2	-65.1	175.8	0	0	0	113.1	L133 L137 Y204 G205	L133-L209 HydrophobicContact CD2-CD2 3.77Å; L137-L209 HydrophobicContact CD2-CD2 4.39Å; Y204-L209 HydrophobicContact CD1-CD1 3.91Å; Y204-L209 HydrophobicContact CD1-CG 3.91Å; Y204-L209 HydrophobicContact CE1-CD1 3.84Å; Y204-L209 HydrophobicContact CE1-CD2 3.87Å; Y204-L209 HydrophobicContact CE1-CG 3.65Å; Y204-L209 PolarHBondContact O-N 2.93Å; Y204-L209 VanDerWaalsContact O-N 3.09Å; G205-L209 WeakPolarHBondContact O-CB 3.37Å; G205-L209 PolarHBondContact O-N 2.97Å
210	D	87.5	Confident	88.6	Confident	134 Å²	134	66.4 Å²	66.4	72%	0.717	33%	0.326	S	S	*	.	I	π-helix	trans	-73.7	-42.7	-177.9	-163.9	38.8	0	0	0	111.8	G205 V206 R212	G205-D210 PolarHBondContact O-N 3.25Å; V206-D210 WeakPolarHBondContact O-CB 3.31Å; D210-R212 VanDerWaalsContact C-N 3.33Å; D210-R212 PolarHBondContact O-N 3.31Å
211	S	83.8	Confident	88.5	Confident	76 Å²	76	69 Å²	69	53%	0.531	34%	0.339	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.7	-14.1	178.5	82.9	0	0	0	0	114.5	R207	R207-S211 WeakPolarHBondContact O-CB 3.42Å; R207-S211 PolarHBondContact O-OG 3.1Å
212	R	82.9	Confident	88.3	Confident	142 Å²	142	66.3 Å²	66.3	54%	0.536	33%	0.329	S	S	.	.	T	Hydrogen-bonded Turn	trans	48.3	60.4	-171.5	-59.8	-177.1	-173.3	176.7	1.4	112.9	I208 D210 R214	I208-R212 WeakPolarHBondContact O-CA 3.08Å; I208-R212 PolarHBondContact O-N 3.28Å; D210-R212 VanDerWaalsContact C-N 3.33Å; D210-R212 PolarHBondContact O-N 3.31Å; R212-R214 PolarHBondContact O-N 3.19Å
213	D	82.1	Confident	88.3	Confident	49 Å²	49	60.6 Å²	60.6	26%	0.262	30%	0.3	S	S	.	.			trans	-62.7	117.7	-178.1	-167.5	-8.9	0	0	0	111.8	W138 I208 N215	W138-D213 WeakPolarHBondContact CH2-O 3.21Å; W138-D213 WeakPolarHBondContact CZ3-O 3.22Å; I208-D213 PolarHBondContact O-N 3.21Å; D213-N215 VanDerWaalsContact C-N 3.33Å; D213-N215 PolarHBondContact O-N 3.03Å; D213-N215 PolarHBondContact OD1-N 3.16Å
214	R	84.4	Confident	88.4	Confident	135 Å²	135	56.7 Å²	56.7	51%	0.509	28%	0.284	S	S	.	.			trans	-78.2	-16.7	-175.1	-61.9	-172.7	172.9	-178.3	-5	113.8	E141 E143 R212 Y216	E141-R214 WeakPolarHBondContact O-CD 3.44Å; E141-R214 WeakPolarHBondContact O-CG 3.49Å; E141-R214 IonicContact OE2-CZ 2.88Å; E141-R214 IonicContact OE2-NE 2.77Å; E141-R214 PolarHBondContact OE2-NE 3.47Å; E141-R214 IonicContact OE2-NH2 2.64Å; E141-R214 PolarHBondContact OE2-NH2 2.89Å; E143-R214 PolarHBondContact N-O 3.29Å; R212-R214 PolarHBondContact O-N 3.19Å; R214-Y216 PolarHBondContact O-N 2.87Å
215	N	87.7	Confident	88.5	Confident	70 Å²	70	58.7 Å²	58.7	37%	0.374	30%	0.298	S	S	.	.			trans	-79.3	89.8	-177.6	-175.9	-7.3	0	0	0	111.3	D213 Q217 G218 I219	D213-N215 VanDerWaalsContact C-N 3.33Å; D213-N215 PolarHBondContact O-N 3.03Å; D213-N215 PolarHBondContact OD1-N 3.16Å; N215-Q217 VanDerWaalsContact C-N 3.27Å; N215-Q217 PolarHBondContact O-N 3.34Å; N215-Q217 WeakPolarHBondContact OD1-CB 3.33Å; N215-Q217 PolarHBondContact OD1-N 3.37Å; N215-G218 PolarHBondContact O-N 2.89Å; N215-G218 VanDerWaalsContact O-N 3.1Å; N215-G218 PolarHBondContact OD1-N 2.98Å; N215-I219 PolarHBondContact O-N 3.34Å
216	Y	86.8	Confident	88.6	Confident	30 Å²	30	57.6 Å²	57.6	12%	0.118	29%	0.286	C	S	.	.	H	α-helix	trans	-63	-31.4	-178	-170.7	-128.2	0	0	0	113.1	I131 L142 C145 F153 R214 G218 I219 V220	I131-Y216 PolarHBondContact O-OH 2.96Å; L142-Y216 HydrophobicContact CD2-CD1 4.42Å; L142-Y216 HydrophobicContact CD2-CD2 3.43Å; L142-Y216 VanDerWaalsContact CD2-CD2 3.43Å; L142-Y216 HydrophobicContact CD2-CE2 3.99Å; L142-Y216 HydrophobicContact CD2-CG 3.71Å; C145-Y216 HydrophobicContact CB-CD1 3.78Å; C145-Y216 HydrophobicContact CB-CE1 4.3Å; C145-Y216 WeakPolarHBondContact SG-CD1 3.33Å; F153-Y216 AromaticContact CZ-CE1 3.74Å; F153-Y216 HydrophobicContact CZ-CE1 3.74Å; F153-Y216 AromaticContact CZ-CZ 3.99Å; R214-Y216 PolarHBondContact O-N 2.87Å; Y216-G218 VanDerWaalsContact C-N 3.32Å; Y216-G218 PolarHBondContact O-N 2.83Å; Y216-I219 HydrophobicContact CD2-CB 4.49Å; Y216-I219 HydrophobicContact CD2-CD1 4.42Å; Y216-I219 PolarHBondContact O-N 3.48Å; Y216-V220 HydrophobicContact CD1-CG2 4.36Å; Y216-V220 HydrophobicContact CD2-CG2 4.42Å; Y216-V220 HydrophobicContact CE1-CG2 4.05Å; Y216-V220 HydrophobicContact CE2-CG2 4.13Å; Y216-V220 WeakPolarHBondContact O-CG2 3.37Å; Y216-V220 PolarHBondContact O-N 3.24Å
217	Q	88.6	Confident	88.8	Confident	67 Å²	67	52.6 Å²	52.6	31%	0.313	26%	0.256	S	S	.	.	H	α-helix	trans	-60.7	-42.4	174.5	-178.8	-174.8	-34	0	0	111.4	N215 I219 V220 Q221	N215-Q217 VanDerWaalsContact C-N 3.27Å; N215-Q217 PolarHBondContact O-N 3.34Å; N215-Q217 WeakPolarHBondContact OD1-CB 3.33Å; N215-Q217 PolarHBondContact OD1-N 3.37Å; Q217-I219 VanDerWaalsContact C-N 3.32Å; Q217-I219 PolarHBondContact O-N 2.98Å; Q217-V220 PolarHBondContact O-N 3.41Å; Q217-Q221 WeakPolarHBondContact O-CB 3.42Å; Q217-Q221 VanDerWaalsContact O-CG 3.32Å; Q217-Q221 WeakPolarHBondContact O-CG 3.34Å; Q217-Q221 PolarHBondContact O-N 3.04Å
218	G	88.4	Confident	89.1	Confident	25 Å²	25	48.4 Å²	48.4	26%	0.258	24%	0.244	S	C	.	.	H	α-helix	trans	-62.5	-38.7	176.7	0	0	0	0	0	112.6	N215 Y216 Q221 Y222	N215-G218 PolarHBondContact O-N 2.89Å; N215-G218 VanDerWaalsContact O-N 3.1Å; N215-G218 PolarHBondContact OD1-N 2.98Å; Y216-G218 VanDerWaalsContact C-N 3.32Å; Y216-G218 PolarHBondContact O-N 2.83Å; G218-Q221 PolarHBondContact O-N 2.84Å; G218-Y222 WeakPolarHBondContact O-CB 3.32Å; G218-Y222 PolarHBondContact O-N 3.4Å
219	I	89.6	Confident	89.4	Confident	0 Å²	0	48.9 Å²	48.9	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-65.9	-45.9	176.9	-58.7	172	0	0	0	111	P134 W138 Y204 I208 N215 Y216 Q217 Y222 A223	P134-I219 HydrophobicContact CB-CD1 4.2Å; P134-I219 HydrophobicContact CG-CD1 3.97Å; P134-I219 HydrophobicContact CG-CG2 4.08Å; W138-I219 HydrophobicContact CH2-CD1 4.15Å; Y204-I219 HydrophobicContact CE2-CG2 4.05Å; I208-I219 HydrophobicContact CD1-CG1 4.45Å; I208-I219 HydrophobicContact CG1-CG1 4.45Å; I208-I219 HydrophobicContact CG2-CD1 3.74Å; I208-I219 HydrophobicContact CG2-CG1 3.89Å; I208-I219 HydrophobicContact CG2-CG2 4.48Å; N215-I219 PolarHBondContact O-N 3.34Å; Y216-I219 HydrophobicContact CD2-CB 4.49Å; Y216-I219 HydrophobicContact CD2-CD1 4.42Å; Y216-I219 PolarHBondContact O-N 3.48Å; Q217-I219 VanDerWaalsContact C-N 3.32Å; Q217-I219 PolarHBondContact O-N 2.98Å; I219-Y222 WeakPolarHBondContact O-CB 3.11Å; I219-Y222 PolarHBondContact O-N 3.38Å; I219-A223 PolarHBondContact O-N 2.91Å
220	V	90.3	Very high	89.7	Confident	0 Å²	0	46.9 Å²	46.9	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-64.4	-41.8	178	178.1	0	0	0	0	110.7	L152 F153 Y216 Q217 Y222 A223 V224	L152-V220 HydrophobicContact CB-CG1 3.63Å; L152-V220 HydrophobicContact CD1-CB 4.48Å; L152-V220 HydrophobicContact CD1-CG1 3.99Å; L152-V220 HydrophobicContact CG-CG1 4.46Å; F153-V220 HydrophobicContact CD1-CG1 4.36Å; F153-V220 HydrophobicContact CE1-CG1 3.99Å; F153-V220 HydrophobicContact CE1-CG2 3.76Å; F153-V220 HydrophobicContact CZ-CG1 4.43Å; F153-V220 HydrophobicContact CZ-CG2 3.76Å; Y216-V220 HydrophobicContact CD1-CG2 4.36Å; Y216-V220 HydrophobicContact CD2-CG2 4.42Å; Y216-V220 HydrophobicContact CE1-CG2 4.05Å; Y216-V220 HydrophobicContact CE2-CG2 4.13Å; Y216-V220 WeakPolarHBondContact O-CG2 3.37Å; Y216-V220 PolarHBondContact O-N 3.24Å; Q217-V220 PolarHBondContact O-N 3.41Å; V220-Y222 VanDerWaalsContact C-N 3.3Å; V220-Y222 PolarHBondContact O-N 2.92Å; V220-A223 PolarHBondContact O-N 3.5Å; V220-V224 HydrophobicContact CG1-CG2 4.45Å; V220-V224 WeakPolarHBondContact O-CG2 3.3Å; V220-V224 PolarHBondContact O-N 2.95Å
221	Q	91.3	Very high	89.9	Confident	96 Å²	96	41 Å²	41	45%	0.449	21%	0.206	S	C	.	.	H	α-helix	trans	-60.5	-39.3	173.6	-75.2	179.8	-5.4	0	0	112.2	L152 Q217 G218 V224 S225	L152-Q221 HydrophobicContact CD1-CG 3.7Å; Q217-Q221 WeakPolarHBondContact O-CB 3.42Å; Q217-Q221 VanDerWaalsContact O-CG 3.32Å; Q217-Q221 WeakPolarHBondContact O-CG 3.34Å; Q217-Q221 PolarHBondContact O-N 3.04Å; G218-Q221 PolarHBondContact O-N 2.84Å; Q221-V224 PolarHBondContact O-N 3.44Å; Q221-S225 PolarHBondContact O-N 3.48Å
222	Y	92	Very high	90.3	Very high	35 Å²	35	44.4 Å²	44.4	14%	0.137	21%	0.212	C	C	.	.	H	α-helix	trans	-63.7	-44.4	175.5	-173.5	-106.9	0	0	0	111.8	F130 Y200 F203 Y204 I208 G218 I219 V220 V224 S225 L226	F130-Y222 HydrophobicContact CD2-CD1 4.23Å; F130-Y222 HydrophobicContact CD2-CE1 4.24Å; F130-Y222 HydrophobicContact CE2-CD1 4.33Å; F130-Y222 AromaticContact CE2-CE1 3.87Å; F130-Y222 HydrophobicContact CE2-CE1 3.87Å; Y200-Y222 WeakPolarHBondContact CA-OH 3.31Å; Y200-Y222 AromaticContact CD1-CE1 3.81Å; Y200-Y222 HydrophobicContact CD1-CE1 3.81Å; Y200-Y222 AromaticContact CD1-CE2 3.95Å; Y200-Y222 HydrophobicContact CD1-CE2 3.95Å; Y200-Y222 AromaticContact CD1-CZ 3.37Å; Y200-Y222 WeakPolarHBondContact CD1-OH 3.37Å; Y200-Y222 HydrophobicContact CE1-CE1 4.46Å; Y200-Y222 AromaticContact CE1-CE2 3.9Å; Y200-Y222 HydrophobicContact CE1-CE2 3.9Å; Y200-Y222 AromaticContact CE1-CZ 3.83Å; Y200-Y222 PolarHBondContact O-OH 2.64Å; F203-Y222 WeakPolarHBondContact CB-OH 3.39Å; F203-Y222 HydrophobicContact CD1-CD2 4.5Å; F203-Y222 HydrophobicContact CD1-CE1 4.36Å; F203-Y222 AromaticContact CD1-CE2 3.58Å; F203-Y222 HydrophobicContact CD1-CE2 3.58Å; F203-Y222 AromaticContact CD1-CZ 3.5Å; F203-Y222 VanDerWaalsContact CD1-CZ 3.5Å; F203-Y222 VanDerWaalsContact CD1-OH 3.3Å; F203-Y222 WeakPolarHBondContact CD1-OH 3.48Å; F203-Y222 HydrophobicContact CE1-CD2 4.42Å; F203-Y222 AromaticContact CE1-CE2 3.79Å; F203-Y222 HydrophobicContact CE1-CE2 3.79Å; Y204-Y222 HydrophobicContact CD2-CD1 4.08Å; Y204-Y222 HydrophobicContact CD2-CE1 4.16Å; I208-Y222 HydrophobicContact CD1-CD1 3.91Å; I208-Y222 HydrophobicContact CD1-CE1 4.44Å; I208-Y222 HydrophobicContact CD1-CG 4.36Å; G218-Y222 WeakPolarHBondContact O-CB 3.32Å; G218-Y222 PolarHBondContact O-N 3.4Å; I219-Y222 WeakPolarHBondContact O-CB 3.11Å; I219-Y222 PolarHBondContact O-N 3.38Å; V220-Y222 VanDerWaalsContact C-N 3.3Å; V220-Y222 PolarHBondContact O-N 2.92Å; Y222-V224 VanDerWaalsContact C-N 3.34Å; Y222-V224 PolarHBondContact O-N 3.02Å; Y222-S225 PolarHBondContact O-N 2.86Å; Y222-S225 PolarHBondContact O-OG 3.28Å; Y222-L226 PolarHBondContact O-N 3.01Å
223	A	92.7	Very high	90.7	Very high	0 Å²	0	38.2 Å²	38.2	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-61	-40.5	174	0	0	0	0	0	112.2	F130 I131 I219 V220 S225 L226 V227	F130-A223 HydrophobicContact CB-CB 4.1Å; I131-A223 HydrophobicContact CD1-CB 4.16Å; I131-A223 HydrophobicContact CG1-CB 3.81Å; I219-A223 PolarHBondContact O-N 2.91Å; V220-A223 PolarHBondContact O-N 3.5Å; A223-S225 VanDerWaalsContact C-N 3.31Å; A223-S225 PolarHBondContact O-N 3.48Å; A223-L226 WeakPolarHBondContact O-CB 3.32Å; A223-L226 PolarHBondContact O-N 2.83Å; A223-V227 WeakPolarHBondContact O-CG2 3.21Å; A223-V227 PolarHBondContact O-N 2.84Å; A223-V227 VanDerWaalsContact O-N 3.17Å
224	V	93.4	Very high	91	Very high	11 Å²	11	36.6 Å²	36.6	7%	0.067	18%	0.18	C	C	.	.	H	α-helix	trans	-59.8	-42.6	174.9	177.6	0	0	0	0	110.9	L152 V156 V220 Q221 Y222 L226 V227 D228	L152-V224 HydrophobicContact CB-CG2 4.23Å; L152-V224 HydrophobicContact CD2-CG2 4.06Å; V156-V224 HydrophobicContact CG2-CB 4.29Å; V156-V224 HydrophobicContact CG2-CG2 3.39Å; V220-V224 HydrophobicContact CG1-CG2 4.45Å; V220-V224 WeakPolarHBondContact O-CG2 3.3Å; V220-V224 PolarHBondContact O-N 2.95Å; Q221-V224 PolarHBondContact O-N 3.44Å; Y222-V224 VanDerWaalsContact C-N 3.34Å; Y222-V224 PolarHBondContact O-N 3.02Å; V224-L226 VanDerWaalsContact C-N 3.3Å; V224-L226 PolarHBondContact O-N 3.16Å; V224-V227 PolarHBondContact O-N 3.39Å; V224-V227 VanDerWaalsContact O-N 3.15Å; V224-D228 PolarHBondContact O-N 3Å
225	S	94.3	Very high	91.1	Very high	42 Å²	42	35.5 Å²	35.5	29%	0.294	18%	0.177	S	C	.	.	H	α-helix	trans	-63.1	-34.6	179.3	79.2	0	0	0	0	113.1	Q221 Y222 A223 D228 A229	Q221-S225 PolarHBondContact O-N 3.48Å; Y222-S225 PolarHBondContact O-N 2.86Å; Y222-S225 PolarHBondContact O-OG 3.28Å; A223-S225 VanDerWaalsContact C-N 3.31Å; A223-S225 PolarHBondContact O-N 3.48Å; S225-D228 PolarHBondContact O-N 3.19Å; S225-A229 PolarHBondContact O-N 3.46Å
226	L	93.3	Very high	91	Very high	0 Å²	0	35.8 Å²	35.8	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-64.9	-45.8	173	173.5	60.8	0	0	0	110.9	P127 F130 Y200 Y222 A223 V224 D228 A229 L230	P127-L226 HydrophobicContact CG-CD2 3.99Å; P127-L226 HydrophobicContact CG-CG 4.27Å; F130-L226 HydrophobicContact CD2-CD2 4.13Å; F130-L226 HydrophobicContact CE2-CD2 3.83Å; Y200-L226 HydrophobicContact CD1-CB 3.76Å; Y200-L226 HydrophobicContact CD1-CD1 3.98Å; Y200-L226 HydrophobicContact CD1-CG 4.31Å; Y200-L226 HydrophobicContact CD2-CD1 3.93Å; Y200-L226 HydrophobicContact CE1-CB 3.82Å; Y200-L226 HydrophobicContact CE1-CD1 4.4Å; Y200-L226 HydrophobicContact CE2-CD1 4.34Å; Y200-L226 HydrophobicContact CG-CB 4.4Å; Y200-L226 HydrophobicContact CG-CD1 3.73Å; Y200-L226 HydrophobicContact CG-CG 4.48Å; Y222-L226 PolarHBondContact O-N 3.01Å; A223-L226 WeakPolarHBondContact O-CB 3.32Å; A223-L226 PolarHBondContact O-N 2.83Å; V224-L226 VanDerWaalsContact C-N 3.3Å; V224-L226 PolarHBondContact O-N 3.16Å; L226-D228 VanDerWaalsContact C-N 3.28Å; L226-D228 PolarHBondContact O-N 3.49Å; L226-A229 PolarHBondContact O-N 3.03Å; L226-L230 HydrophobicContact CD1-CD1 4.17Å; L226-L230 HydrophobicContact CD1-CG 4.15Å; L226-L230 HydrophobicContact CG-CD1 4.11Å; L226-L230 VanDerWaalsContact O-CG 3.31Å; L226-L230 WeakPolarHBondContact O-CG 3.42Å; L226-L230 PolarHBondContact O-N 3.42Å
227	V	94.4	Very high	90.9	Very high	0 Å²	0	34.8 Å²	34.8	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-61	-40.3	177.5	-178.6	0	0	0	0	110.9	P127 V156 K159 L160 A223 V224 L230 L231	P127-V227 HydrophobicContact CB-CG2 3.47Å; P127-V227 VanDerWaalsContact CB-CG2 3.47Å; P127-V227 HydrophobicContact CG-CG2 3.55Å; V156-V227 HydrophobicContact CG1-CG2 4.4Å; K159-V227 HydrophobicContact CB-CG1 3.4Å; K159-V227 HydrophobicContact CD-CG1 4.08Å; K159-V227 HydrophobicContact CG-CG1 4.35Å; L160-V227 HydrophobicContact CD2-CG1 4.43Å; L160-V227 HydrophobicContact CD2-CG2 4.16Å; L160-V227 HydrophobicContact CG-CG2 4.43Å; A223-V227 WeakPolarHBondContact O-CG2 3.21Å; A223-V227 PolarHBondContact O-N 2.84Å; A223-V227 VanDerWaalsContact O-N 3.17Å; V224-V227 PolarHBondContact O-N 3.39Å; V224-V227 VanDerWaalsContact O-N 3.15Å; V227-L230 PolarHBondContact O-N 3.45Å; V227-L231 HydrophobicContact CG1-CD1 4.37Å; V227-L231 WeakPolarHBondContact O-CB 3.41Å; V227-L231 WeakPolarHBondContact O-CG 3.22Å; V227-L231 PolarHBondContact O-N 3.21Å
228	D	94.1	Very high	90.5	Very high	50 Å²	50	34.5 Å²	34.5	27%	0.267	18%	0.176	S	C	.	.	H	α-helix	trans	-62.8	-46.7	176.1	-74	-30.1	0	0	0	111.8	K159 V224 S225 L226 L230 L231 F232	K159-D228 WeakPolarHBondContact CD-OD1 3.36Å; K159-D228 WeakPolarHBondContact CE-OD1 3.29Å; K159-D228 IonicContact NZ-OD1 3.76Å; K159-D228 PolarHBondContact NZ-OD1 3.33Å; K159-D228 IonicContact NZ-OD2 3.18Å; K159-D228 PolarHBondContact NZ-OD2 2Å; V224-D228 PolarHBondContact O-N 3Å; S225-D228 PolarHBondContact O-N 3.19Å; L226-D228 VanDerWaalsContact C-N 3.28Å; L226-D228 PolarHBondContact O-N 3.49Å; D228-L230 VanDerWaalsContact C-N 3.34Å; D228-L230 PolarHBondContact O-N 2.9Å; D228-L231 PolarHBondContact O-N 2.83Å; D228-F232 HydrophobicContact CB-CE2 4.47Å; D228-F232 WeakPolarHBondContact O-CD2 3.45Å; D228-F232 PolarHBondContact O-N 2.9Å
229	A	93.5	Very high	90	Very high	16 Å²	16	36.8 Å²	36.8	13%	0.132	19%	0.185	C	C	.	.	H	α-helix	trans	-59	-44.3	175.4	0	0	0	0	0	112.1	F196 S225 L226 L231 F232 I233	F196-A229 HydrophobicContact CD1-CB 4.1Å; F196-A229 HydrophobicContact CE1-CB 4.18Å; S225-A229 PolarHBondContact O-N 3.46Å; L226-A229 PolarHBondContact O-N 3.03Å; A229-L231 PolarHBondContact O-N 3.44Å; A229-F232 PolarHBondContact O-N 3.01Å; A229-I233 WeakPolarHBondContact O-CG1 3.47Å; A229-I233 PolarHBondContact O-N 3.44Å
230	L	92.3	Very high	89.1	Confident	7 Å²	7	39.6 Å²	39.6	4%	0.037	20%	0.2	C	C	.	.	H	α-helix	trans	-63.9	-39.2	177.2	-69.2	173.7	0	0	0	112.2	A123 P127 L163 I193 V197 L226 V227 D228 I233 H234	A123-L230 HydrophobicContact CB-CD1 4.31Å; A123-L230 HydrophobicContact CB-CD2 4.18Å; P127-L230 HydrophobicContact CG-CD1 4.42Å; L163-L230 HydrophobicContact CD1-CB 3.61Å; I193-L230 HydrophobicContact CG2-CD2 4.42Å; V197-L230 HydrophobicContact CG2-CD2 4.26Å; L226-L230 HydrophobicContact CD1-CD1 4.17Å; L226-L230 HydrophobicContact CD1-CG 4.15Å; L226-L230 HydrophobicContact CG-CD1 4.11Å; L226-L230 VanDerWaalsContact O-CG 3.31Å; L226-L230 WeakPolarHBondContact O-CG 3.42Å; L226-L230 PolarHBondContact O-N 3.42Å; V227-L230 PolarHBondContact O-N 3.45Å; D228-L230 VanDerWaalsContact C-N 3.34Å; D228-L230 PolarHBondContact O-N 2.9Å; L230-I233 PolarHBondContact O-N 3.44Å; L230-H234 WeakPolarHBondContact O-CB 3.08Å; L230-H234 PolarHBondContact O-N 2.99Å
231	L	92.6	Very high	88.1	Confident	10 Å²	10	41 Å²	41	5%	0.052	21%	0.207	C	C	.	.	H	α-helix	trans	-65.4	-41.2	173.7	-81.4	175.9	0	0	0	112.2	K159 I162 L163 V227 D228 A229 I233 H234 Y235	K159-L231 HydrophobicContact CB-CD1 3.68Å; K159-L231 HydrophobicContact CD-CD1 4.19Å; K159-L231 HydrophobicContact CG-CD1 3.72Å; I162-L231 HydrophobicContact CB-CD2 4.47Å; I162-L231 HydrophobicContact CG2-CD2 4.01Å; L163-L231 HydrophobicContact CB-CD2 4.02Å; L163-L231 HydrophobicContact CD1-CD2 4.33Å; L163-L231 HydrophobicContact CD1-CG 4.43Å; V227-L231 HydrophobicContact CG1-CD1 4.37Å; V227-L231 WeakPolarHBondContact O-CB 3.41Å; V227-L231 WeakPolarHBondContact O-CG 3.22Å; V227-L231 PolarHBondContact O-N 3.21Å; D228-L231 PolarHBondContact O-N 2.83Å; A229-L231 PolarHBondContact O-N 3.44Å; L231-I233 PolarHBondContact O-N 3.08Å; L231-H234 CarbonylContact O-C 3.55Å; L231-H234 WeakPolarHBondContact O-CB 2.87Å; L231-H234 PolarHBondContact O-N 3.08Å; L231-H234 VanDerWaalsContact O-N 3.15Å; L231-Y235 HydrophobicContact CB-CE2 4.36Å; L231-Y235 VanDerWaalsContact O-CD2 3.3Å; L231-Y235 WeakPolarHBondContact O-CD2 3.48Å; L231-Y235 PolarHBondContact O-N 2.64Å
232	F	92	Very high	87	Confident	147 Å²	147	39.6 Å²	39.6	65%	0.645	20%	0.2	S	C	*	.	H	α-helix	trans	-62.2	-42.7	175	-78.5	-63.4	0	0	0	112.1	D228 A229 H234 Y235 L236	D228-F232 HydrophobicContact CB-CE2 4.47Å; D228-F232 WeakPolarHBondContact O-CD2 3.45Å; D228-F232 PolarHBondContact O-N 2.9Å; A229-F232 PolarHBondContact O-N 3.01Å; F232-H234 VanDerWaalsContact C-N 3.27Å; F232-H234 PolarHBondContact O-N 3.17Å; F232-Y235 PolarHBondContact O-N 2.78Å; F232-L236 WeakPolarHBondContact O-CB 3.13Å; F232-L236 PolarHBondContact O-N 3.49Å
233	I	90.4	Very high	85.3	Confident	12 Å²	12	44.3 Å²	44.3	6%	0.062	23%	0.227	C	C	.	.	H	α-helix	trans	-62.3	-38.6	174	-65.4	167.5	0	0	0	110.5	L189 L192 I193 F196 A229 L230 L231 L236 A237	L189-I233 HydrophobicContact CD2-CG2 4.25Å; L192-I233 HydrophobicContact CD2-CD1 4.18Å; L192-I233 HydrophobicContact CD2-CG1 3.9Å; L192-I233 HydrophobicContact CD2-CG2 4.16Å; L192-I233 HydrophobicContact CG-CD1 4.09Å; L192-I233 HydrophobicContact CG-CG1 4.38Å; I193-I233 HydrophobicContact CD1-CG2 4.29Å; I193-I233 HydrophobicContact CG1-CG2 3.76Å; F196-I233 HydrophobicContact CB-CD1 4.39Å; F196-I233 HydrophobicContact CD1-CD1 4.48Å; F196-I233 HydrophobicContact CD2-CD1 3.96Å; F196-I233 HydrophobicContact CE2-CD1 4.37Å; F196-I233 HydrophobicContact CG-CD1 4.01Å; A229-I233 WeakPolarHBondContact O-CG1 3.47Å; A229-I233 PolarHBondContact O-N 3.44Å; L230-I233 PolarHBondContact O-N 3.44Å; L231-I233 PolarHBondContact O-N 3.08Å; I233-L236 PolarHBondContact O-N 3.49Å; I233-A237 WeakPolarHBondContact O-CB 3.41Å; I233-A237 PolarHBondContact O-N 2.92Å
234	H	88.1	Confident	83.4	Confident	16 Å²	16	53.2 Å²	53.2	7%	0.074	26%	0.261	C	S	.	.	H	α-helix	trans	-65.3	-42.8	175.6	-175.1	65.8	0	0	0	112.6	G166 L170 L230 L231 F232 A237 I238	G166-H234 VanDerWaalsContact CA-NE2 3.27Å; G166-H234 WeakPolarHBondContact CA-NE2 3.49Å; G166-H234 PolarHBondContact O-CE1 2.99Å; L170-H234 WeakPolarHBondContact CD1-CE1 3.39Å; L230-H234 WeakPolarHBondContact O-CB 3.08Å; L230-H234 PolarHBondContact O-N 2.99Å; L231-H234 CarbonylContact O-C 3.55Å; L231-H234 WeakPolarHBondContact O-CB 2.87Å; L231-H234 PolarHBondContact O-N 3.08Å; L231-H234 VanDerWaalsContact O-N 3.15Å; F232-H234 VanDerWaalsContact C-N 3.27Å; F232-H234 PolarHBondContact O-N 3.17Å; H234-A237 WeakPolarHBondContact O-CB 3.2Å; H234-A237 PolarHBondContact O-N 2.85Å; H234-I238 WeakPolarHBondContact NE2-CD1 3.33Å; H234-I238 WeakPolarHBondContact O-CG1 3.41Å; H234-I238 PolarHBondContact O-N 3.24Å
235	Y	88.2	Confident	81.1	Confident	111 Å²	111	56 Å²	56	44%	0.435	27%	0.273	S	S	.	.	H	α-helix	trans	-64.3	-40.3	173.9	-64.6	-38.3	0	0	0	112	L231 F232 A237 I238 V239	L231-Y235 HydrophobicContact CB-CE2 4.36Å; L231-Y235 VanDerWaalsContact O-CD2 3.3Å; L231-Y235 WeakPolarHBondContact O-CD2 3.48Å; L231-Y235 PolarHBondContact O-N 2.64Å; F232-Y235 PolarHBondContact O-N 2.78Å; Y235-A237 VanDerWaalsContact C-N 3.29Å; Y235-A237 PolarHBondContact O-N 3.04Å; Y235-I238 HydrophobicContact CD1-CD1 4.26Å; Y235-I238 WeakPolarHBondContact O-CB 3.36Å; Y235-I238 PolarHBondContact O-N 2.92Å; Y235-V239 WeakPolarHBondContact O-CG2 3.28Å; Y235-V239 PolarHBondContact O-N 3.39Å
236	L	85.4	Confident	79.3	Confident	76 Å²	76	61.7 Å²	61.7	40%	0.398	30%	0.299	S	S	.	.	H	α-helix	trans	-60.9	-40.5	172.2	-178.7	64.7	0	0	0	111.2	F232 I233 V239 L240	F232-L236 WeakPolarHBondContact O-CB 3.13Å; F232-L236 PolarHBondContact O-N 3.49Å; I233-L236 PolarHBondContact O-N 3.49Å; L236-V239 PolarHBondContact O-N 2.83Å; L236-L240 HydrophobicContact CD1-CD1 3.94Å; L236-L240 HydrophobicContact CD1-CG 3.98Å; L236-L240 HydrophobicContact CD2-CD1 4.36Å; L236-L240 HydrophobicContact CG-CD1 3.79Å; L236-L240 HydrophobicContact CG-CG 4.23Å; L236-L240 WeakPolarHBondContact O-CB 3.32Å; L236-L240 VanDerWaalsContact O-CG 3.3Å; L236-L240 WeakPolarHBondContact O-CG 3.27Å; L236-L240 PolarHBondContact O-N 3.44Å
237	A	83.1	Confident	77.8	Confident	9 Å²	9	65.6 Å²	65.6	7%	0.074	32%	0.318	C	S	.	.	H	α-helix	trans	-61.4	-44	174.1	0	0	0	0	0	111.7	L170 L189 I233 H234 Y235 L241	L170-A237 HydrophobicContact CD1-CB 4.43Å; L189-A237 HydrophobicContact CD1-CB 3.62Å; L189-A237 HydrophobicContact CD2-CB 4.18Å; I233-A237 WeakPolarHBondContact O-CB 3.41Å; I233-A237 PolarHBondContact O-N 2.92Å; H234-A237 WeakPolarHBondContact O-CB 3.2Å; H234-A237 PolarHBondContact O-N 2.85Å; Y235-A237 VanDerWaalsContact C-N 3.29Å; Y235-A237 PolarHBondContact O-N 3.04Å; A237-L241 HydrophobicContact CB-CD1 4.47Å; A237-L241 WeakPolarHBondContact O-CB 3.47Å; A237-L241 WeakPolarHBondContact O-CG 3.18Å; A237-L241 PolarHBondContact O-N 3.18Å
238	I	80.9	Confident	76.5	Confident	62 Å²	62	68.6 Å²	68.6	32%	0.318	34%	0.337	S	S	.	.	H	α-helix	trans	-60	-47.7	174.3	-69.5	166.6	0	0	0	110.3	H234 Y235 E242	H234-I238 WeakPolarHBondContact NE2-CD1 3.33Å; H234-I238 WeakPolarHBondContact O-CG1 3.41Å; H234-I238 PolarHBondContact O-N 3.24Å; Y235-I238 HydrophobicContact CD1-CD1 4.26Å; Y235-I238 WeakPolarHBondContact O-CB 3.36Å; Y235-I238 PolarHBondContact O-N 2.92Å; I238-E242 HydrophobicContact CG2-CB 4.44Å; I238-E242 HydrophobicContact CG2-CG 3.93Å; I238-E242 WeakPolarHBondContact O-CA 3.4Å; I238-E242 WeakPolarHBondContact O-CB 3.34Å; I238-E242 WeakPolarHBondContact O-CG 3.33Å; I238-E242 PolarHBondContact O-N 3.5Å
239	V	78	Confident	75.8	Confident	72 Å²	72	66.5 Å²	66.5	44%	0.436	33%	0.326	S	S	.	.	H	α-helix	trans	-60.7	-53	179.2	166	0	0	0	0	110.9	Y235 L236 L241 L243	Y235-V239 WeakPolarHBondContact O-CG2 3.28Å; Y235-V239 PolarHBondContact O-N 3.39Å; L236-V239 PolarHBondContact O-N 2.83Å; V239-L241 VanDerWaalsContact C-N 3.32Å; V239-L241 PolarHBondContact O-N 3.39Å; V239-L243 HydrophobicContact CB-CD1 4.03Å; V239-L243 HydrophobicContact CG1-CD1 3.5Å; V239-L243 HydrophobicContact CG2-CD1 4.2Å; V239-L243 VanDerWaalsContact O-CB 3.26Å; V239-L243 WeakPolarHBondContact O-CB 3.46Å; V239-L243 PolarHBondContact O-N 2.83Å
240	L	71.3	Confident	75.6	Confident	60 Å²	60	66.1 Å²	66.1	31%	0.314	32%	0.321	S	S	.	.	H	α-helix	trans	-67.1	-31.8	-176.7	-68.2	175.7	0	0	0	113.1	L236	L236-L240 HydrophobicContact CD1-CD1 3.94Å; L236-L240 HydrophobicContact CD1-CG 3.98Å; L236-L240 HydrophobicContact CD2-CD1 4.36Å; L236-L240 HydrophobicContact CG-CD1 3.79Å; L236-L240 HydrophobicContact CG-CG 4.23Å; L236-L240 WeakPolarHBondContact O-CB 3.32Å; L236-L240 VanDerWaalsContact O-CG 3.3Å; L236-L240 WeakPolarHBondContact O-CG 3.27Å; L236-L240 PolarHBondContact O-N 3.44Å
241	L	69.4	Low	75.6	Confident	28 Å²	28	67.9 Å²	67.9	15%	0.147	33%	0.332	C	S	.	.	H	α-helix	trans	-90.2	-40.5	-178.8	-61.2	173.8	0	0	0	112.6	L170 R186 L189 A237 V239 Q245	L170-L241 HydrophobicContact CD2-CD1 4.38Å; R186-L241 HydrophobicContact CG-CD2 4.12Å; L189-L241 HydrophobicContact CD1-CD1 4.48Å; A237-L241 HydrophobicContact CB-CD1 4.47Å; A237-L241 WeakPolarHBondContact O-CB 3.47Å; A237-L241 WeakPolarHBondContact O-CG 3.18Å; A237-L241 PolarHBondContact O-N 3.18Å; V239-L241 VanDerWaalsContact C-N 3.32Å; V239-L241 PolarHBondContact O-N 3.39Å; L241-Q245 WeakPolarHBondContact O-CB 3.47Å; L241-Q245 VanDerWaalsContact O-CG 3.27Å; L241-Q245 WeakPolarHBondContact O-CG 3.3Å; L241-Q245 PolarHBondContact O-OE1 3.28Å
242	E	67	Low	75.6	Confident	67 Å²	67	67.4 Å²	67.4	31%	0.313	33%	0.33	S	S	.	.	H	α-helix	trans	-86.9	-39.7	-176.4	-60.8	-71.1	154.9	0	0	113.6	R173 I238 R244 Q245	R173-E242 IonicContact CZ-OE1 3.56Å; R173-E242 IonicContact CZ-OE2 2.62Å; R173-E242 IonicContact NH1-OE1 3.87Å; R173-E242 PolarHBondContact NH1-OE1 3.37Å; R173-E242 IonicContact NH1-OE2 3.65Å; R173-E242 PolarHBondContact NH1-OE2 3.12Å; I238-E242 HydrophobicContact CG2-CB 4.44Å; I238-E242 HydrophobicContact CG2-CG 3.93Å; I238-E242 WeakPolarHBondContact O-CA 3.4Å; I238-E242 WeakPolarHBondContact O-CB 3.34Å; I238-E242 WeakPolarHBondContact O-CG 3.33Å; I238-E242 PolarHBondContact O-N 3.5Å; E242-R244 PolarHBondContact O-N 3.44Å; E242-Q245 CarbonylContact O-C 3.58Å; E242-Q245 VanDerWaalsContact O-C 3.31Å; E242-Q245 WeakPolarHBondContact O-CA 3.48Å; E242-Q245 PolarHBondContact O-N 2.99Å
243	L	56.6	Low	75.8	Confident	134 Å²	134	63.5 Å²	63.5	70%	0.702	31%	0.314	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.4	-25	-179	-77.2	153.7	0	0	0	112.6	V239 Q245	V239-L243 HydrophobicContact CB-CD1 4.03Å; V239-L243 HydrophobicContact CG1-CD1 3.5Å; V239-L243 HydrophobicContact CG2-CD1 4.2Å; V239-L243 VanDerWaalsContact O-CB 3.26Å; V239-L243 WeakPolarHBondContact O-CB 3.46Å; V239-L243 PolarHBondContact O-N 2.83Å; L243-Q245 VanDerWaalsContact C-N 3.28Å
244	R	52.5	Low	76.1	Confident	187 Å²	187	63 Å²	63	71%	0.706	31%	0.311	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.8	-13.2	171.6	-161.9	172	-179.4	156.1	1.6	112.4	E242	E242-R244 PolarHBondContact O-N 3.44Å
245	Q	45.3	Very low	76.4	Confident	69 Å²	69	64.1 Å²	64.1	32%	0.322	32%	0.319	S	S	.	.			trans	-121.3	52.5	-173	-69.3	-172.6	-40.3	0	0	113.8	L241 E242 L243 Q247	L241-Q245 WeakPolarHBondContact O-CB 3.47Å; L241-Q245 VanDerWaalsContact O-CG 3.27Å; L241-Q245 WeakPolarHBondContact O-CG 3.3Å; L241-Q245 PolarHBondContact O-OE1 3.28Å; E242-Q245 CarbonylContact O-C 3.58Å; E242-Q245 VanDerWaalsContact O-C 3.31Å; E242-Q245 WeakPolarHBondContact O-CA 3.48Å; E242-Q245 PolarHBondContact O-N 2.99Å; L243-Q245 VanDerWaalsContact C-N 3.28Å; Q245-Q247 HydrophobicContact CB-CB 4.38Å; Q245-Q247 HydrophobicContact CB-CG 3.73Å; Q245-Q247 HydrophobicContact CG-CG 3.7Å; Q245-Q247 PolarHBondContact O-N 3.48Å
246	L	56.1	Low	76.6	Confident	163 Å²	163	58.9 Å²	58.9	85%	0.853	30%	0.298	S	S	*	.			trans	-65.2	59.1	140.5	-76.8	162.8	0	0	0	108.6
247	Q	62.6	Low	76.8	Confident	82 Å²	82	58.2 Å²	58.2	38%	0.383	30%	0.3	S	S	.	.			trans	-74	124.6	-175.9	-83.8	-172.6	-15.7	0	0	108.1	Q245 V249	Q245-Q247 HydrophobicContact CB-CB 4.38Å; Q245-Q247 HydrophobicContact CB-CG 3.73Å; Q245-Q247 HydrophobicContact CG-CG 3.7Å; Q245-Q247 PolarHBondContact O-N 3.48Å; Q247-V249 PolarHBondContact O-N 2.85Å; Q247-V249 VanDerWaalsContact O-N 3.16Å
248	P	67.2	Low	76.9	Confident	62 Å²	62	59.8 Å²	59.8	40%	0.403	31%	0.309	S	S	.	.			trans	-59.7	126.6	174.4	26.9	-33.4	0	0	0	108.9	L267 I497	P248-L267 CarbonylContact C-O 3.5Å; P248-L267 WeakPolarHBondContact CA-O 3.27Å; P248-I497 HydrophobicContact CB-CD1 3.83Å; P248-I497 HydrophobicContact CG-CD1 4.25Å
249	V	79.4	Confident	77	Confident	7 Å²	7	60.1 Å²	60.1	4%	0.042	31%	0.312	C	S	.	.			trans	-97.9	-35.8	173.1	-161.9	0	0	0	0	110.2	R176 Q247 L267 G268 I497	R176-V249 VanDerWaalsContact CZ-CG2 3.49Å; R176-V249 VanDerWaalsContact NH1-CA 3.3Å; R176-V249 VanDerWaalsContact NH1-CB 3.31Å; Q247-V249 PolarHBondContact O-N 2.85Å; Q247-V249 VanDerWaalsContact O-N 3.16Å; V249-L267 PolarHBondContact N-O 2.98Å; V249-G268 VanDerWaalsContact CG2-C 3.47Å; V249-I497 WeakPolarHBondContact O-CB 3.35Å; V249-I497 PolarHBondContact O-N 3.4Å
250	F	88.3	Confident	77.4	Confident	8 Å²	8	58.9 Å²	58.9	4%	0.035	31%	0.313	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.7	142.6	-170.2	-56.8	-73.1	0	0	0	109.3	S266 L267 H269 L475 V494 K495 K496	F250-S266 CarbonylContact O-C 3.59Å; F250-S266 WeakPolarHBondContact O-CA 3.36Å; F250-L267 PolarHBondContact N-O 3.16Å; F250-L267 PolarHBondContact O-N 2.79Å; F250-H269 AromaticContact CE2-ND1 3.91Å; F250-L475 HydrophobicContact CD2-CB 3.76Å; F250-L475 HydrophobicContact CD2-CD1 4.02Å; F250-L475 HydrophobicContact CE2-CB 3.66Å; F250-L475 WeakPolarHBondContact CE2-O 3.46Å; F250-L475 HydrophobicContact CG-CB 4.36Å; F250-L475 HydrophobicContact CZ-CB 4.16Å; F250-L475 WeakPolarHBondContact CZ-O 3.14Å; F250-V494 HydrophobicContact CB-CG1 3.94Å; F250-V494 HydrophobicContact CD1-CG1 3.83Å; F250-V494 HydrophobicContact CG-CG1 3.97Å; F250-K495 CarbonylContact C-O 3.47Å; F250-K495 VanDerWaalsContact CA-O 3.22Å; F250-K495 WeakPolarHBondContact CA-O 3.44Å; F250-K496 HydrophobicContact CD1-CB 4.16Å; F250-K496 HydrophobicContact CE1-CB 4.21Å; F250-K496 HydrophobicContact CE1-CG 4.33Å
251	T	92.4	Very high	78.3	Confident	43 Å²	43	57.6 Å²	57.6	26%	0.264	31%	0.305	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-104	121.6	163.6	-56.8	0	0	0	0	107.7	F264 Y265 K495 I497	T251-F264 HydrophobicContact CG2-CB 4.34Å; T251-F264 HydrophobicContact CG2-CD1 4.17Å; T251-Y265 CarbonylContact C-O 3.57Å; T251-Y265 WeakPolarHBondContact CA-O 3.13Å; T251-K495 PolarHBondContact N-O 3.36Å; T251-K495 PolarHBondContact O-N 2.99Å; T251-I497 WeakPolarHBondContact OG1-CG1 3.38Å
252	L	94.3	Very high	79.4	Confident	0 Å²	0	58.7 Å²	58.7	0%	0	32%	0.315	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.6	124.2	173.5	-61	176	0	0	0	108.9	V254 F264 Y265 L267 V279 F481 V492 N493 V494	L252-V254 HydrophobicContact CB-CG2 4.43Å; L252-F264 CarbonylContact O-C 3.5Å; L252-F264 VanDerWaalsContact O-CA 3.26Å; L252-F264 WeakPolarHBondContact O-CA 3.44Å; L252-Y265 PolarHBondContact N-O 3.23Å; L252-Y265 PolarHBondContact O-N 3.37Å; L252-L267 HydrophobicContact CD1-CD1 3.2Å; L252-L267 HydrophobicContact CD1-CG 3.66Å; L252-L267 HydrophobicContact CG-CD1 4.22Å; L252-L267 HydrophobicContact CG-CG 4.33Å; L252-V279 HydrophobicContact CD1-CG2 3.68Å; L252-F481 HydrophobicContact CD2-CE1 4.49Å; L252-V492 HydrophobicContact CB-CG1 4.04Å; L252-V492 HydrophobicContact CD1-CG1 4.31Å; L252-V492 HydrophobicContact CD2-CG1 3.75Å; L252-V492 HydrophobicContact CG-CG1 4.28Å; L252-N493 CarbonylContact C-O 3.56Å; L252-N493 WeakPolarHBondContact CA-O 3.37Å; L252-V494 HydrophobicContact CD2-CB 4.02Å; L252-V494 HydrophobicContact CD2-CG1 3.97Å; L252-V494 HydrophobicContact CD2-CG2 3.51Å
253	Q	95.8	Very high	80.7	Confident	66 Å²	66	60.9 Å²	60.9	31%	0.308	32%	0.321	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-94	113.8	163.7	-177.1	-177.8	7.4	0	0	108.1	V255 F264 V492 N493	Q253-V255 HydrophobicContact CG-CG2 3.92Å; Q253-F264 HydrophobicContact CB-CD1 3.9Å; Q253-F264 HydrophobicContact CB-CE1 3.66Å; Q253-F264 HydrophobicContact CG-CD1 4.1Å; Q253-F264 HydrophobicContact CG-CE1 3.52Å; Q253-F264 HydrophobicContact CG-CZ 3.94Å; Q253-V492 WeakPolarHBondContact O-CA 3.41Å; Q253-N493 HydrophobicContact CB-CB 4.36Å; Q253-N493 PolarHBondContact N-O 2.72Å; Q253-N493 PolarHBondContact O-N 2.75Å
254	V	95.6	Very high	82.5	Confident	0 Å²	0	60.6 Å²	60.6	0%	0	31%	0.314	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.9	120.6	178.2	-177.2	0	0	0	0	107.9	L252 S262 R263 Y265 V279 F287 L490 V491 V492	L252-V254 HydrophobicContact CB-CG2 4.43Å; V254-S262 CarbonylContact O-C 3.31Å; V254-S262 WeakPolarHBondContact O-CA 3.4Å; V254-R263 PolarHBondContact N-O 3.44Å; V254-R263 PolarHBondContact O-N 3.4Å; V254-Y265 HydrophobicContact CB-CD2 4.38Å; V254-Y265 HydrophobicContact CB-CE2 4.16Å; V254-Y265 HydrophobicContact CG2-CD2 3.61Å; V254-Y265 HydrophobicContact CG2-CE2 3.82Å; V254-V279 HydrophobicContact CB-CG1 4.45Å; V254-V279 HydrophobicContact CG1-CG1 3.83Å; V254-V279 HydrophobicContact CG2-CG1 3.74Å; V254-V279 HydrophobicContact CG2-CG2 3.99Å; V254-F287 HydrophobicContact CB-CZ 4.12Å; V254-F287 HydrophobicContact CG1-CE2 4.28Å; V254-F287 HydrophobicContact CG1-CZ 3.8Å; V254-L490 HydrophobicContact CG1-CB 4.05Å; V254-L490 HydrophobicContact CG1-CD1 4.42Å; V254-L490 HydrophobicContact CG1-CD2 4.42Å; V254-V491 WeakPolarHBondContact CA-O 3.35Å; V254-V492 HydrophobicContact CG1-CG2 4.31Å; V254-V492 HydrophobicContact CG2-CG1 4.09Å; V254-V492 HydrophobicContact CG2-CG2 4.1Å
255	V	95.1	Very high	84.4	Confident	40 Å²	40	52.7 Å²	52.7	24%	0.242	29%	0.285	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.3	128.2	-178.5	-172.6	0	0	0	0	109.7	Q253 E261 L490 V491	Q253-V255 HydrophobicContact CG-CG2 3.92Å; V255-E261 WeakPolarHBondContact CA-O 3.34Å; V255-L490 WeakPolarHBondContact O-CA 3.35Å; V255-V491 PolarHBondContact N-O 3.2Å; V255-V491 PolarHBondContact O-N 2.9Å
256	R	91.5	Very high	86.6	Confident	1 Å²	1	53 Å²	53	0%	0.004	29%	0.294	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-77	124.5	171.2	-176.6	161.2	63.4	-152.5	-4.6	109.7	T258 D259 G260 E261 Y283 F287 T288 F488 L490	R256-T258 PolarHBondContact O-N 3.15Å; R256-D259 WeakPolarHBondContact CB-OD1 3.33Å; R256-D259 WeakPolarHBondContact CG-OD1 3.38Å; R256-D259 IonicContact CZ-OD1 3.34Å; R256-D259 IonicContact CZ-OD2 3.59Å; R256-D259 VanDerWaalsContact CZ-OD2 3.24Å; R256-D259 VanDerWaalsContact NE-CG 3.3Å; R256-D259 IonicContact NE-OD1 2.74Å; R256-D259 PolarHBondContact NE-OD1 2.93Å; R256-D259 IonicContact NE-OD2 2.78Å; R256-D259 PolarHBondContact NE-OD2 3.43Å; R256-D259 VanDerWaalsContact NE-OD2 3.13Å; R256-D259 IonicContact NH2-OD1 3.08Å; R256-D259 IonicContact NH2-OD2 3.13Å; R256-D259 PolarHBondContact NH2-OD2 2.9Å; R256-G260 VanDerWaalsContact O-CA 3.31Å; R256-G260 WeakPolarHBondContact O-CA 3.44Å; R256-G260 PolarHBondContact O-N 3.23Å; R256-E261 IonicContact CZ-OE2 3.98Å; R256-E261 PolarHBondContact N-O 2.94Å; R256-E261 IonicContact NH1-OE2 3.56Å; R256-E261 IonicContact NH2-OE2 3.59Å; R256-E261 PolarHBondContact NH2-OE2 3.01Å; R256-Y283 PolarHBondContact NH1-OH 2.91Å; R256-F287 HydrophobicContact CB-CE1 4.39Å; R256-T288 PolarHBondContact NH1-O 3.32Å; R256-T288 PolarHBondContact NH2-O 2.85Å; R256-F488 HydrophobicContact CG-CD2 3.71Å; R256-F488 HydrophobicContact CG-CE2 4.22Å; R256-F488 HydrophobicContact CG-CG 4.36Å; R256-L490 HydrophobicContact CB-CD2 3.95Å; R256-L490 HydrophobicContact CG-CD2 4.27Å
257	S	89.7	Confident	88	Confident	63 Å²	63	46 Å²	46	44%	0.441	26%	0.257	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.4	-20.2	-169.9	56.7	0	0	0	0	115	S489	S257-S489 WeakPolarHBondContact CB-O 3.37Å; S257-S489 VanDerWaalsContact CB-OG 3.3Å; S257-S489 WeakPolarHBondContact CB-OG 3.27Å; S257-S489 PolarHBondContact N-O 3.3Å; S257-S489 PolarHBondContact OG-N 2.83Å; S257-S489 PolarHBondContact OG-O 2.84Å; S257-S489 VanDerWaalsContact OG-O 3.05Å; S257-S489 PolarHBondContact OG-OG 3.16Å
258	T	85.3	Confident	88.9	Confident	42 Å²	42	42.8 Å²	42.8	26%	0.258	25%	0.247	S	C	.	.	T	Hydrogen-bonded Turn	trans	-90.3	-46.6	-171.8	47.5	0	0	0	0	113.4	R256 Y290 L295 F488	R256-T258 PolarHBondContact O-N 3.15Å; T258-Y290 HydrophobicContact CG2-CE2 4.11Å; T258-Y290 WeakPolarHBondContact OG1-CE2 3.13Å; T258-L295 HydrophobicContact CG2-CD1 4.37Å; T258-L295 WeakPolarHBondContact O-CD2 3.35Å; T258-F488 HydrophobicContact CG2-CB 3.5Å
259	D	84.1	Confident	89.5	Confident	69 Å²	69	45.8 Å²	45.8	37%	0.369	26%	0.255	S	S	.	.	T	Hydrogen-bonded Turn	trans	-115.9	-3	-177.6	60.8	-4.4	0	0	0	114.3	R256 E261 L295	R256-D259 WeakPolarHBondContact CB-OD1 3.33Å; R256-D259 WeakPolarHBondContact CG-OD1 3.38Å; R256-D259 IonicContact CZ-OD1 3.34Å; R256-D259 IonicContact CZ-OD2 3.59Å; R256-D259 VanDerWaalsContact CZ-OD2 3.24Å; R256-D259 VanDerWaalsContact NE-CG 3.3Å; R256-D259 IonicContact NE-OD1 2.74Å; R256-D259 PolarHBondContact NE-OD1 2.93Å; R256-D259 IonicContact NE-OD2 2.78Å; R256-D259 PolarHBondContact NE-OD2 3.43Å; R256-D259 VanDerWaalsContact NE-OD2 3.13Å; R256-D259 IonicContact NH2-OD1 3.08Å; R256-D259 IonicContact NH2-OD2 3.13Å; R256-D259 PolarHBondContact NH2-OD2 2.9Å; D259-E261 PolarHBondContact O-N 3.42Å; D259-E261 PolarHBondContact OD1-N 3.37Å; D259-L295 HydrophobicContact CB-CD2 4.14Å
260	G	86.9	Confident	89.5	Confident	45 Å²	45	47.6 Å²	47.6	46%	0.464	26%	0.264	S	S	.	.			trans	73.6	11.4	176	0	0	0	0	0	114.3	R256 S262	R256-G260 VanDerWaalsContact O-CA 3.31Å; R256-G260 WeakPolarHBondContact O-CA 3.44Å; R256-G260 PolarHBondContact O-N 3.23Å; G260-S262 PolarHBondContact O-N 2.9Å
261	E	89.1	Confident	89.2	Confident	34 Å²	34	48.3 Å²	48.3	16%	0.159	27%	0.27	C	S	.	.			trans	-59.3	127.5	172.6	-172	178.4	171	0	0	108.8	V255 R256 D259 F287 T288	V255-E261 WeakPolarHBondContact CA-O 3.34Å; R256-E261 IonicContact CZ-OE2 3.98Å; R256-E261 PolarHBondContact N-O 2.94Å; R256-E261 IonicContact NH1-OE2 3.56Å; R256-E261 IonicContact NH2-OE2 3.59Å; R256-E261 PolarHBondContact NH2-OE2 3.01Å; D259-E261 PolarHBondContact O-N 3.42Å; D259-E261 PolarHBondContact OD1-N 3.37Å; E261-F287 HydrophobicContact CB-CD1 4.33Å; E261-F287 HydrophobicContact CB-CE1 4.42Å; E261-F287 HydrophobicContact CG-CD1 4.02Å; E261-F287 HydrophobicContact CG-CE1 4.26Å; E261-F287 WeakPolarHBondContact O-CE1 3.1Å; E261-T288 PolarHBondContact OE1-N 3.27Å; E261-T288 VanDerWaalsContact OE1-N 3.15Å; E261-T288 PolarHBondContact OE2-N 2.94Å; E261-T288 PolarHBondContact OE2-OG1 3.31Å
262	S	93.3	Very high	89	Confident	51 Å²	51	46.3 Å²	46.3	36%	0.357	26%	0.258	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.8	140.1	-176	71.2	0	0	0	0	112.6	V254 G260	V254-S262 CarbonylContact O-C 3.31Å; V254-S262 WeakPolarHBondContact O-CA 3.4Å; G260-S262 PolarHBondContact O-N 2.9Å
263	R	93.6	Very high	88.7	Confident	112 Å²	112	50.4 Å²	50.4	42%	0.423	28%	0.277	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.7	156	173.4	-63.2	-64.5	-172.5	156.2	5.8	110.3	V254 Y265 D286 F287	V254-R263 PolarHBondContact N-O 3.44Å; V254-R263 PolarHBondContact O-N 3.4Å; R263-Y265 HydrophobicContact CB-CE1 4.49Å; R263-Y265 HydrophobicContact CB-CE2 3.97Å; R263-D286 PolarHBondContact NE-O 2.94Å; R263-D286 PolarHBondContact NH2-O 3.3Å; R263-D286 VanDerWaalsContact NH2-O 3.09Å; R263-F287 HydrophobicContact CB-CE2 3.69Å; R263-F287 HydrophobicContact CB-CZ 3.86Å; R263-F287 HydrophobicContact CG-CD2 3.93Å; R263-F287 HydrophobicContact CG-CE1 4.37Å; R263-F287 HydrophobicContact CG-CE2 3.51Å; R263-F287 HydrophobicContact CG-CZ 3.75Å
264	F	93.9	Very high	88.1	Confident	129 Å²	129	55.3 Å²	55.3	57%	0.566	29%	0.293	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-114.9	132.9	178.9	-63.6	-88.5	0	0	0	110.2	T251 L252 Q253	T251-F264 HydrophobicContact CG2-CB 4.34Å; T251-F264 HydrophobicContact CG2-CD1 4.17Å; L252-F264 CarbonylContact O-C 3.5Å; L252-F264 VanDerWaalsContact O-CA 3.26Å; L252-F264 WeakPolarHBondContact O-CA 3.44Å; Q253-F264 HydrophobicContact CB-CD1 3.9Å; Q253-F264 HydrophobicContact CB-CE1 3.66Å; Q253-F264 HydrophobicContact CG-CD1 4.1Å; Q253-F264 HydrophobicContact CG-CE1 3.52Å; Q253-F264 HydrophobicContact CG-CZ 3.94Å
265	Y	92.7	Very high	87.8	Confident	21 Å²	21	55.3 Å²	55.3	8%	0.082	29%	0.293	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.9	145.1	178.8	-58.5	-62.9	0	0	0	111.1	T251 L252 V254 R263 N282 D286 F287	T251-Y265 CarbonylContact C-O 3.57Å; T251-Y265 WeakPolarHBondContact CA-O 3.13Å; L252-Y265 PolarHBondContact N-O 3.23Å; L252-Y265 PolarHBondContact O-N 3.37Å; V254-Y265 HydrophobicContact CB-CD2 4.38Å; V254-Y265 HydrophobicContact CB-CE2 4.16Å; V254-Y265 HydrophobicContact CG2-CD2 3.61Å; V254-Y265 HydrophobicContact CG2-CE2 3.82Å; R263-Y265 HydrophobicContact CB-CE1 4.49Å; R263-Y265 HydrophobicContact CB-CE2 3.97Å; Y265-N282 HydrophobicContact CD1-CB 4.15Å; Y265-N282 HydrophobicContact CE1-CB 3.56Å; Y265-N282 HydrophobicContact CE2-CB 4.05Å; Y265-N282 VanDerWaalsContact CZ-CB 3.49Å; Y265-N282 PolarHBondContact OH-O 3.19Å; Y265-D286 WeakPolarHBondContact CE1-OD2 3.21Å; Y265-D286 WeakPolarHBondContact OH-CB 3.32Å; Y265-D286 PolarHBondContact OH-OD2 2.84Å; Y265-D286 VanDerWaalsContact OH-OD2 3.11Å; Y265-F287 HydrophobicContact CE2-CE2 4.2Å; Y265-F287 WeakPolarHBondContact OH-CE2 3.37Å
266	S	90.6	Very high	87.5	Confident	74 Å²	74	53.7 Å²	53.7	52%	0.517	28%	0.283	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-110.1	116.2	-177.7	-64.3	0	0	0	0	109.5	F250	F250-S266 CarbonylContact O-C 3.59Å; F250-S266 WeakPolarHBondContact O-CA 3.36Å
267	L	87.1	Confident	87.4	Confident	16 Å²	16	58.6 Å²	58.6	8%	0.084	31%	0.309	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.6	151.1	-175.2	-64.3	-166.3	0	0	0	113.6	P248 V249 F250 L252 L270 A275 V278 L475	P248-L267 CarbonylContact C-O 3.5Å; P248-L267 WeakPolarHBondContact CA-O 3.27Å; V249-L267 PolarHBondContact N-O 2.98Å; F250-L267 PolarHBondContact N-O 3.16Å; F250-L267 PolarHBondContact O-N 2.79Å; L252-L267 HydrophobicContact CD1-CD1 3.2Å; L252-L267 HydrophobicContact CD1-CG 3.66Å; L252-L267 HydrophobicContact CG-CD1 4.22Å; L252-L267 HydrophobicContact CG-CG 4.33Å; L267-L270 HydrophobicContact CB-CD1 4.37Å; L267-L270 HydrophobicContact CD1-CD1 4.06Å; L267-L270 HydrophobicContact CD2-CD1 4.47Å; L267-A275 HydrophobicContact CD1-CB 3.87Å; L267-V278 HydrophobicContact CD1-CB 4.5Å; L267-V278 HydrophobicContact CD1-CG1 4.49Å; L267-V278 HydrophobicContact CD2-CB 4.44Å; L267-V278 HydrophobicContact CD2-CG1 3.67Å; L267-L475 HydrophobicContact CD1-CD1 4.47Å
268	G	81.9	Confident	87.4	Confident	16 Å²	16	57.5 Å²	57.5	17%	0.165	30%	0.3	C	S	.	.			trans	-74.1	-166.1	172.1	0	0	0	0	0	113.9	V249 L270	V249-G268 VanDerWaalsContact CG2-C 3.47Å; G268-L270 PolarHBondContact O-N 3.02Å
269	H	78.3	Confident	87.8	Confident	124 Å²	124	55.5 Å²	55.5	57%	0.574	29%	0.288	S	S	*	.	S	Bend	trans	-74.1	94.7	170.1	-74.4	-68.7	0	0	0	109.6	R176 F250	R176-H269 PolarHBondContact NH2-CD2 3.23Å; R176-H269 PolarHBondContact NH2-NE2 2.88Å; F250-H269 AromaticContact CE2-ND1 3.91Å
270	L	79.1	Confident	88.1	Confident	46 Å²	46	53.3 Å²	53.3	24%	0.241	28%	0.276	C	S	.	.			trans	-118.8	158.9	176.5	-66.6	171	0	0	0	109.7	L267 G268 R274 G474 L475	L267-L270 HydrophobicContact CB-CD1 4.37Å; L267-L270 HydrophobicContact CD1-CD1 4.06Å; L267-L270 HydrophobicContact CD2-CD1 4.47Å; G268-L270 PolarHBondContact O-N 3.02Å; L270-R274 HydrophobicContact CB-CB 4.22Å; L270-R274 HydrophobicContact CD2-CB 4.27Å; L270-G474 CarbonylContact O-C 3.53Å; L270-G474 WeakPolarHBondContact O-CA 3.37Å; L270-L475 HydrophobicContact CB-CD1 4.49Å; L270-L475 WeakPolarHBondContact O-CG 3.26Å; L270-L475 PolarHBondContact O-N 2.97Å
271	S	84	Confident	88.2	Confident	23 Å²	23	57.6 Å²	57.6	16%	0.161	28%	0.284	C	S	.	.	B	Isolated β-bridge	trans	-71.5	159.1	165.7	62.6	0	0	0	0	110.7	Q273 R274 A275 N473	S271-Q273 PolarHBondContact O-N 2.67Å; S271-R274 PolarHBondContact O-N 3.41Å; S271-R274 VanDerWaalsContact O-N 3.13Å; S271-R274 WeakPolarHBondContact OG-CG 3.4Å; S271-R274 PolarHBondContact OG-N 3.46Å; S271-A275 WeakPolarHBondContact O-CB 3.49Å; S271-A275 PolarHBondContact O-N 2.94Å; S271-N473 CarbonylContact C-O 3.56Å; S271-N473 WeakPolarHBondContact CA-O 3.29Å; S271-N473 WeakPolarHBondContact CB-O 3.44Å
272	I	86.9	Confident	88.2	Confident	0 Å²	0	57.7 Å²	57.7	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-56.4	-40.6	176.5	-58.8	170.7	0	0	0	110.3	A275 A276 L465 E469 V471 N473 L475 I479 F481	I272-A275 PolarHBondContact O-N 3.45Å; I272-A276 VanDerWaalsContact O-CB 3.31Å; I272-A276 WeakPolarHBondContact O-CB 3.3Å; I272-A276 PolarHBondContact O-N 2.66Å; I272-L465 HydrophobicContact CG2-CD1 4.24Å; I272-L465 HydrophobicContact CG2-CD2 4.3Å; I272-E469 HydrophobicContact CD1-CB 4.13Å; I272-V471 PolarHBondContact N-O 3.27Å; I272-N473 PolarHBondContact N-O 3.05Å; I272-L475 HydrophobicContact CG1-CD2 4.28Å; I272-I479 HydrophobicContact CD1-CD1 4.23Å; I272-I479 HydrophobicContact CD1-CG2 4.32Å; I272-F481 HydrophobicContact CG2-CB 4.07Å; I272-F481 HydrophobicContact CG2-CD1 3.87Å; I272-F481 HydrophobicContact CG2-CD2 4.26Å; I272-F481 HydrophobicContact CG2-CE1 4.34Å; I272-F481 HydrophobicContact CG2-CG 3.81Å
273	Q	88.4	Confident	88	Confident	87 Å²	87	55.5 Å²	55.5	41%	0.407	27%	0.269	S	S	.	.	H	α-helix	trans	-58.7	-48.7	173.9	-74.1	171.6	-18.4	0	0	113.5	S271 A276 L277 L465 V471	S271-Q273 PolarHBondContact O-N 2.67Å; Q273-A276 WeakPolarHBondContact O-CB 3.47Å; Q273-A276 PolarHBondContact O-N 3.42Å; Q273-L277 PolarHBondContact O-N 3.42Å; Q273-L465 HydrophobicContact CG-CD2 4.06Å; Q273-V471 HydrophobicContact CG-CB 3.72Å; Q273-V471 HydrophobicContact CG-CG2 3.86Å; Q273-V471 WeakPolarHBondContact CG-O 3.38Å; Q273-V471 PolarHBondContact N-O 2.88Å; Q273-V471 VanDerWaalsContact N-O 3.08Å
274	R	82.9	Confident	87.6	Confident	169 Å²	169	52 Å²	52	64%	0.638	26%	0.256	S	S	*	.	H	α-helix	trans	-68.6	-39.2	-179.4	-73.6	-178.3	179.1	-167.3	0	111.1	L270 S271 A276 L277 V278	L270-R274 HydrophobicContact CB-CB 4.22Å; L270-R274 HydrophobicContact CD2-CB 4.27Å; S271-R274 PolarHBondContact O-N 3.41Å; S271-R274 VanDerWaalsContact O-N 3.13Å; S271-R274 WeakPolarHBondContact OG-CG 3.4Å; S271-R274 PolarHBondContact OG-N 3.46Å; R274-A276 VanDerWaalsContact C-N 3.32Å; R274-A276 PolarHBondContact O-N 2.86Å; R274-L277 PolarHBondContact O-N 3.27Å; R274-V278 WeakPolarHBondContact O-CG2 3.42Å; R274-V278 PolarHBondContact O-N 3.47Å
275	A	88.8	Confident	87.2	Confident	0 Å²	0	52 Å²	52	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-61.3	-41.6	174.5	0	0	0	0	0	111.7	L267 S271 I272 L277 V278 V279 L475 F481	L267-A275 HydrophobicContact CD1-CB 3.87Å; S271-A275 WeakPolarHBondContact O-CB 3.49Å; S271-A275 PolarHBondContact O-N 2.94Å; I272-A275 PolarHBondContact O-N 3.45Å; A275-L277 PolarHBondContact O-N 2.99Å; A275-V278 PolarHBondContact O-N 2.88Å; A275-V279 VanDerWaalsContact O-CG2 3.31Å; A275-V279 WeakPolarHBondContact O-CG2 3.43Å; A275-V279 PolarHBondContact O-N 3.29Å; A275-L475 HydrophobicContact CB-CD1 3.77Å; A275-L475 HydrophobicContact CB-CD2 3.96Å; A275-L475 HydrophobicContact CB-CG 4.09Å; A275-F481 HydrophobicContact CB-CZ 4.32Å
276	A	90.4	Very high	87	Confident	5 Å²	5	53.3 Å²	53.3	4%	0.041	27%	0.265	C	S	.	.	H	α-helix	trans	-57.8	-44.4	175.5	0	0	0	0	0	112.7	I272 Q273 R274 V279 L280 L465 F481 L483	I272-A276 VanDerWaalsContact O-CB 3.31Å; I272-A276 WeakPolarHBondContact O-CB 3.3Å; I272-A276 PolarHBondContact O-N 2.66Å; Q273-A276 WeakPolarHBondContact O-CB 3.47Å; Q273-A276 PolarHBondContact O-N 3.42Å; R274-A276 VanDerWaalsContact C-N 3.32Å; R274-A276 PolarHBondContact O-N 2.86Å; A276-V279 PolarHBondContact O-N 2.85Å; A276-L280 WeakPolarHBondContact O-CG 3.06Å; A276-L280 PolarHBondContact O-N 2.93Å; A276-L465 HydrophobicContact CB-CD1 4.01Å; A276-L465 HydrophobicContact CB-CD2 4.05Å; A276-F481 HydrophobicContact CB-CE2 4.04Å; A276-L483 HydrophobicContact CB-CD2 3.59Å
277	L	89.4	Confident	86.8	Confident	105 Å²	105	49.9 Å²	49.9	55%	0.55	24%	0.24	S	C	.	.	H	α-helix	trans	-62.7	-45.9	177.2	-68.1	174.9	0	0	0	111.9	Q273 R274 A275 V279 L280 E281	Q273-L277 PolarHBondContact O-N 3.42Å; R274-L277 PolarHBondContact O-N 3.27Å; A275-L277 PolarHBondContact O-N 2.99Å; L277-V279 VanDerWaalsContact C-N 3.28Å; L277-V279 PolarHBondContact O-N 3.01Å; L277-L280 WeakPolarHBondContact O-CB 3.37Å; L277-L280 PolarHBondContact O-N 3.22Å; L277-E281 WeakPolarHBondContact O-CG 3.49Å; L277-E281 PolarHBondContact O-N 3.05Å
278	V	89.6	Confident	86.7	Confident	39 Å²	39	51.1 Å²	51.1	24%	0.236	25%	0.249	C	C	.	.	H	α-helix	trans	-62.2	-37.7	177.2	177.9	0	0	0	0	111.5	L267 R274 A275 L280 E281 N282	L267-V278 HydrophobicContact CD1-CB 4.5Å; L267-V278 HydrophobicContact CD1-CG1 4.49Å; L267-V278 HydrophobicContact CD2-CB 4.44Å; L267-V278 HydrophobicContact CD2-CG1 3.67Å; R274-V278 WeakPolarHBondContact O-CG2 3.42Å; R274-V278 PolarHBondContact O-N 3.47Å; A275-V278 PolarHBondContact O-N 2.88Å; V278-L280 VanDerWaalsContact C-N 3.34Å; V278-E281 PolarHBondContact O-N 2.65Å; V278-N282 WeakPolarHBondContact O-CB 3.47Å; V278-N282 PolarHBondContact O-N 2.84Å; V278-N282 PolarHBondContact O-ND2 2.84Å; V278-N282 VanDerWaalsContact O-ND2 3.16Å
279	V	92.4	Very high	86.7	Confident	1 Å²	1	51.3 Å²	51.3	1%	0.006	25%	0.246	C	C	.	.	H	α-helix	trans	-63.1	-40.7	173.7	169.1	0	0	0	0	111.2	L252 V254 A275 A276 L277 Y283 L483 V492	L252-V279 HydrophobicContact CD1-CG2 3.68Å; V254-V279 HydrophobicContact CB-CG1 4.45Å; V254-V279 HydrophobicContact CG1-CG1 3.83Å; V254-V279 HydrophobicContact CG2-CG1 3.74Å; V254-V279 HydrophobicContact CG2-CG2 3.99Å; A275-V279 VanDerWaalsContact O-CG2 3.31Å; A275-V279 WeakPolarHBondContact O-CG2 3.43Å; A275-V279 PolarHBondContact O-N 3.29Å; A276-V279 PolarHBondContact O-N 2.85Å; L277-V279 VanDerWaalsContact C-N 3.28Å; L277-V279 PolarHBondContact O-N 3.01Å; V279-Y283 VanDerWaalsContact O-CB 3.29Å; V279-Y283 WeakPolarHBondContact O-CB 3.41Å; V279-Y283 PolarHBondContact O-N 3.13Å; V279-L483 HydrophobicContact CB-CD1 4.03Å; V279-L483 HydrophobicContact CG1-CD1 3.59Å; V279-V492 HydrophobicContact CG1-CG2 4.08Å; V279-V492 HydrophobicContact CG2-CG1 4.46Å; V279-V492 HydrophobicContact CG2-CG2 4.47Å
280	L	90.1	Very high	86.9	Confident	23 Å²	23	47.1 Å²	47.1	12%	0.12	23%	0.225	C	C	.	.	H	α-helix	trans	-67.6	-42.6	177.5	-68.9	176.8	0	0	0	112.4	A276 L277 V278 N282 Y283 Y284 W463 L483 L490	A276-L280 WeakPolarHBondContact O-CG 3.06Å; A276-L280 PolarHBondContact O-N 2.93Å; L277-L280 WeakPolarHBondContact O-CB 3.37Å; L277-L280 PolarHBondContact O-N 3.22Å; V278-L280 VanDerWaalsContact C-N 3.34Å; L280-N282 VanDerWaalsContact C-N 3.33Å; L280-N282 PolarHBondContact O-N 3.43Å; L280-Y283 WeakPolarHBondContact O-CB 3.37Å; L280-Y283 PolarHBondContact O-N 2.87Å; L280-Y284 WeakPolarHBondContact O-CD2 3.2Å; L280-Y284 PolarHBondContact O-N 2.8Å; L280-Y284 VanDerWaalsContact O-N 3.15Å; L280-W463 HydrophobicContact CD1-CB 3.81Å; L280-W463 HydrophobicContact CD1-CD2 4.34Å; L280-W463 HydrophobicContact CD1-CG 3.8Å; L280-W463 HydrophobicContact CD2-CB 4.39Å; L280-W463 HydrophobicContact CD2-CD2 3.31Å; L280-W463 VanDerWaalsContact CD2-CE2 3.47Å; L280-W463 HydrophobicContact CD2-CE3 3.65Å; L280-W463 HydrophobicContact CD2-CG 3.67Å; L280-W463 HydrophobicContact CD2-CH2 4.12Å; L280-W463 HydrophobicContact CD2-CZ2 3.88Å; L280-W463 HydrophobicContact CD2-CZ3 4.03Å; L280-W463 HydrophobicContact CG-CD2 4.48Å; L280-W463 HydrophobicContact CG-CG 4.41Å; L280-L483 HydrophobicContact CD2-CB 4.48Å; L280-L483 HydrophobicContact CD2-CD1 3.84Å; L280-L483 HydrophobicContact CG-CD1 3.99Å; L280-L490 HydrophobicContact CD2-CD1 4.34Å
281	E	88.8	Confident	87.1	Confident	135 Å²	135	45.6 Å²	45.6	63%	0.631	22%	0.217	S	C	*	.	H	α-helix	trans	-57.7	-47.6	174.9	-72	173.4	-174.3	0	0	111.2	L277 V278 Y283 Y284 K285	L277-E281 WeakPolarHBondContact O-CG 3.49Å; L277-E281 PolarHBondContact O-N 3.05Å; V278-E281 PolarHBondContact O-N 2.65Å; E281-Y283 VanDerWaalsContact C-N 3.35Å; E281-Y283 PolarHBondContact O-N 3.29Å; E281-Y284 PolarHBondContact O-N 2.88Å; E281-K285 PolarHBondContact O-N 3.08Å
282	N	89.4	Confident	86.9	Confident	36 Å²	36	47.1 Å²	47.1	19%	0.193	23%	0.227	C	C	.	.	H	α-helix	trans	-70.2	-30.4	177.1	-68.4	-35.6	0	0	0	112.7	Y265 V278 L280 Y284 K285 D286	Y265-N282 HydrophobicContact CD1-CB 4.15Å; Y265-N282 HydrophobicContact CE1-CB 3.56Å; Y265-N282 HydrophobicContact CE2-CB 4.05Å; Y265-N282 VanDerWaalsContact CZ-CB 3.49Å; Y265-N282 PolarHBondContact OH-O 3.19Å; V278-N282 WeakPolarHBondContact O-CB 3.47Å; V278-N282 PolarHBondContact O-N 2.84Å; V278-N282 PolarHBondContact O-ND2 2.84Å; V278-N282 VanDerWaalsContact O-ND2 3.16Å; L280-N282 VanDerWaalsContact C-N 3.33Å; L280-N282 PolarHBondContact O-N 3.43Å; N282-Y284 PolarHBondContact O-N 3.04Å; N282-K285 PolarHBondContact O-N 3.47Å; N282-D286 WeakPolarHBondContact O-CB 3.45Å; N282-D286 PolarHBondContact O-N 2.97Å
283	Y	88.9	Confident	86.5	Confident	5 Å²	5	50 Å²	50	2%	0.02	24%	0.242	C	C	.	.	H	α-helix	trans	-58.4	-48.7	174.5	171.7	-98.8	0	0	0	111.2	R256 V279 L280 E281 K285 F287 W463 F488 L490	R256-Y283 PolarHBondContact NH1-OH 2.91Å; V279-Y283 VanDerWaalsContact O-CB 3.29Å; V279-Y283 WeakPolarHBondContact O-CB 3.41Å; V279-Y283 PolarHBondContact O-N 3.13Å; L280-Y283 WeakPolarHBondContact O-CB 3.37Å; L280-Y283 PolarHBondContact O-N 2.87Å; E281-Y283 VanDerWaalsContact C-N 3.35Å; E281-Y283 PolarHBondContact O-N 3.29Å; Y283-K285 PolarHBondContact O-N 3.37Å; Y283-F287 HydrophobicContact CD2-CB 3.62Å; Y283-F287 AromaticContact CD2-CD1 3.82Å; Y283-F287 HydrophobicContact CD2-CD1 3.82Å; Y283-F287 AromaticContact CD2-CD2 3.59Å; Y283-F287 HydrophobicContact CD2-CD2 3.59Å; Y283-F287 HydrophobicContact CD2-CE1 4.35Å; Y283-F287 HydrophobicContact CD2-CE2 4.13Å; Y283-F287 AromaticContact CD2-CG 3.39Å; Y283-F287 HydrophobicContact CD2-CG 3.39Å; Y283-F287 HydrophobicContact CD2-CZ 4.48Å; Y283-F287 HydrophobicContact CE2-CB 3.57Å; Y283-F287 AromaticContact CE2-CD1 3.78Å; Y283-F287 HydrophobicContact CE2-CD1 3.78Å; Y283-F287 HydrophobicContact CE2-CD2 4.3Å; Y283-F287 AromaticContact CE2-CG 3.63Å; Y283-F287 HydrophobicContact CE2-CG 3.63Å; Y283-F287 HydrophobicContact CG-CB 4.45Å; Y283-F287 HydrophobicContact CG-CD2 4.35Å; Y283-F287 HydrophobicContact CG-CG 4.42Å; Y283-F287 WeakPolarHBondContact O-CB 3.21Å; Y283-F287 PolarHBondContact O-N 3.08Å; Y283-W463 HydrophobicContact CD1-CH2 4.49Å; Y283-W463 HydrophobicContact CD1-CZ2 4.04Å; Y283-W463 HydrophobicContact CE1-CH2 4.39Å; Y283-W463 AromaticContact CE1-CZ2 3.96Å; Y283-W463 HydrophobicContact CE1-CZ2 3.96Å; Y283-F488 HydrophobicContact CE1-CZ 4.24Å; Y283-F488 HydrophobicContact CE2-CE2 4.2Å; Y283-F488 AromaticContact CZ-CE2 3.84Å; Y283-F488 AromaticContact CZ-CZ 3.73Å; Y283-F488 WeakPolarHBondContact OH-CE2 3.17Å; Y283-F488 WeakPolarHBondContact OH-CZ 3.42Å; Y283-L490 HydrophobicContact CD1-CD1 4.46Å; Y283-L490 HydrophobicContact CD2-CD1 3.61Å; Y283-L490 HydrophobicContact CD2-CD2 3.77Å; Y283-L490 HydrophobicContact CD2-CG 4.3Å; Y283-L490 HydrophobicContact CE2-CD1 4.25Å; Y283-L490 HydrophobicContact CE2-CD2 3.77Å; Y283-L490 HydrophobicContact CG-CD1 3.75Å
284	Y	86.2	Confident	85.9	Confident	37 Å²	37	50.2 Å²	50.2	15%	0.145	25%	0.245	C	C	.	.	H	α-helix	trans	-65.6	-23.5	179.3	-73.2	-63.4	0	0	0	113.4	L280 E281 N282 P449 T450 L451 W458 W463	L280-Y284 WeakPolarHBondContact O-CD2 3.2Å; L280-Y284 PolarHBondContact O-N 2.8Å; L280-Y284 VanDerWaalsContact O-N 3.15Å; E281-Y284 PolarHBondContact O-N 2.88Å; N282-Y284 PolarHBondContact O-N 3.04Å; Y284-P449 WeakPolarHBondContact O-CB 3.36Å; Y284-T450 HydrophobicContact CD1-CG2 3.89Å; Y284-T450 HydrophobicContact CE1-CG2 4.22Å; Y284-L451 WeakPolarHBondContact O-CG 3.3Å; Y284-W458 AromaticContact CD1-CE3 3.95Å; Y284-W458 HydrophobicContact CD1-CE3 3.95Å; Y284-W458 HydrophobicContact CD1-CZ3 4.47Å; Y284-W458 HydrophobicContact CE1-CB 4.34Å; Y284-W458 HydrophobicContact CE1-CD2 4.39Å; Y284-W458 AromaticContact CE1-CE3 3.59Å; Y284-W458 HydrophobicContact CE1-CE3 3.59Å; Y284-W458 HydrophobicContact CE1-CZ3 4.28Å; Y284-W463 AromaticContact CZ-NE1 3.86Å; Y284-W463 PolarHBondContact OH-NE1 3.22Å
285	K	85.1	Confident	85.3	Confident	129 Å²	129	44.8 Å²	44.8	56%	0.561	23%	0.229	S	C	*	.	H	α-helix	trans	-91.7	-35.9	-178.7	-175.6	-168.9	164.7	-172.7	0	114.8	E281 N282 Y283 P449	E281-K285 PolarHBondContact O-N 3.08Å; N282-K285 PolarHBondContact O-N 3.47Å; Y283-K285 PolarHBondContact O-N 3.37Å; K285-P449 WeakPolarHBondContact O-CB 3.46Å
286	D	87.8	Confident	84.3	Confident	50 Å²	50	47.2 Å²	47.2	27%	0.267	24%	0.244	S	C	.	.	H	α-helix	trans	-117.9	-19.3	-166.5	-57	-33.7	0	0	0	114.3	R263 Y265 N282	R263-D286 PolarHBondContact NE-O 2.94Å; R263-D286 PolarHBondContact NH2-O 3.3Å; R263-D286 VanDerWaalsContact NH2-O 3.09Å; Y265-D286 WeakPolarHBondContact CE1-OD2 3.21Å; Y265-D286 WeakPolarHBondContact OH-CB 3.32Å; Y265-D286 PolarHBondContact OH-OD2 2.84Å; Y265-D286 VanDerWaalsContact OH-OD2 3.11Å; N282-D286 WeakPolarHBondContact O-CB 3.45Å; N282-D286 PolarHBondContact O-N 2.97Å
287	F	87.3	Confident	83.2	Confident	1 Å²	1	47.3 Å²	47.3	0%	0.004	24%	0.244	C	C	.	.	S	Bend	trans	-87.9	141.4	178.9	-78.7	-111.5	0	0	0	111.4	V254 R256 E261 R263 Y265 Y283 P449 T450	V254-F287 HydrophobicContact CB-CZ 4.12Å; V254-F287 HydrophobicContact CG1-CE2 4.28Å; V254-F287 HydrophobicContact CG1-CZ 3.8Å; R256-F287 HydrophobicContact CB-CE1 4.39Å; E261-F287 HydrophobicContact CB-CD1 4.33Å; E261-F287 HydrophobicContact CB-CE1 4.42Å; E261-F287 HydrophobicContact CG-CD1 4.02Å; E261-F287 HydrophobicContact CG-CE1 4.26Å; E261-F287 WeakPolarHBondContact O-CE1 3.1Å; R263-F287 HydrophobicContact CB-CE2 3.69Å; R263-F287 HydrophobicContact CB-CZ 3.86Å; R263-F287 HydrophobicContact CG-CD2 3.93Å; R263-F287 HydrophobicContact CG-CE1 4.37Å; R263-F287 HydrophobicContact CG-CE2 3.51Å; R263-F287 HydrophobicContact CG-CZ 3.75Å; Y265-F287 HydrophobicContact CE2-CE2 4.2Å; Y265-F287 WeakPolarHBondContact OH-CE2 3.37Å; Y283-F287 HydrophobicContact CD2-CB 3.62Å; Y283-F287 AromaticContact CD2-CD1 3.82Å; Y283-F287 HydrophobicContact CD2-CD1 3.82Å; Y283-F287 AromaticContact CD2-CD2 3.59Å; Y283-F287 HydrophobicContact CD2-CD2 3.59Å; Y283-F287 HydrophobicContact CD2-CE1 4.35Å; Y283-F287 HydrophobicContact CD2-CE2 4.13Å; Y283-F287 AromaticContact CD2-CG 3.39Å; Y283-F287 HydrophobicContact CD2-CG 3.39Å; Y283-F287 HydrophobicContact CD2-CZ 4.48Å; Y283-F287 HydrophobicContact CE2-CB 3.57Å; Y283-F287 AromaticContact CE2-CD1 3.78Å; Y283-F287 HydrophobicContact CE2-CD1 3.78Å; Y283-F287 HydrophobicContact CE2-CD2 4.3Å; Y283-F287 AromaticContact CE2-CG 3.63Å; Y283-F287 HydrophobicContact CE2-CG 3.63Å; Y283-F287 HydrophobicContact CG-CB 4.45Å; Y283-F287 HydrophobicContact CG-CD2 4.35Å; Y283-F287 HydrophobicContact CG-CG 4.42Å; Y283-F287 WeakPolarHBondContact O-CB 3.21Å; Y283-F287 PolarHBondContact O-N 3.08Å; F287-P449 WeakPolarHBondContact O-CA 3.43Å; F287-T450 PolarHBondContact O-N 3.42Å
288	T	85.7	Confident	82	Confident	43 Å²	43	45.6 Å²	45.6	26%	0.264	24%	0.241	S	C	.	.	B	Isolated β-bridge	trans	-66.6	151.5	170.7	72.3	0	0	0	0	110.6	R256 E261 Y290 A447	R256-T288 PolarHBondContact NH1-O 3.32Å; R256-T288 PolarHBondContact NH2-O 2.85Å; E261-T288 PolarHBondContact OE1-N 3.27Å; E261-T288 VanDerWaalsContact OE1-N 3.15Å; E261-T288 PolarHBondContact OE2-N 2.94Å; E261-T288 PolarHBondContact OE2-OG1 3.31Å; T288-Y290 PolarHBondContact O-N 3.04Å; T288-A447 HydrophobicContact CG2-CB 4Å; T288-A447 WeakPolarHBondContact CG2-O 3.48Å
289	I	82.1	Confident	80.8	Confident	20 Å²	20	51.1 Å²	51.1	10%	0.103	26%	0.262	C	S	.	.	P	Polyproline II helix	trans	-60.5	131	179.4	-170.8	159.7	0	0	0	111.4	N291 Y417 Y453	I289-N291 PolarHBondContact O-N 3.34Å; I289-Y417 HydrophobicContact CD1-CD1 3.78Å; I289-Y417 HydrophobicContact CD1-CE1 3.43Å; I289-Y417 VanDerWaalsContact CD1-CE1 3.43Å; I289-Y417 HydrophobicContact CG1-CE1 3.78Å; I289-Y417 HydrophobicContact CG2-CD2 4.5Å; I289-Y417 HydrophobicContact CG2-CE1 4.07Å; I289-Y417 HydrophobicContact CG2-CE2 4.04Å; I289-Y453 HydrophobicContact CB-CD2 4.03Å; I289-Y453 HydrophobicContact CB-CE2 3.86Å; I289-Y453 HydrophobicContact CD1-CD1 4.25Å; I289-Y453 HydrophobicContact CD1-CD2 3.56Å; I289-Y453 HydrophobicContact CD1-CE2 4.16Å; I289-Y453 HydrophobicContact CD1-CG 3.61Å; I289-Y453 HydrophobicContact CG1-CD2 4.39Å; I289-Y453 HydrophobicContact CG2-CD2 4.22Å; I289-Y453 HydrophobicContact CG2-CE2 3.67Å
290	Y	82	Confident	79.5	Confident	36 Å²	36	57.6 Å²	57.6	14%	0.141	29%	0.29	C	S	.	.	P	Polyproline II helix	trans	-61.3	124.6	178.1	170.9	-118.4	0	0	0	111	T258 T288 P292 L295 Y417 D487 F488	T258-Y290 HydrophobicContact CG2-CE2 4.11Å; T258-Y290 WeakPolarHBondContact OG1-CE2 3.13Å; T288-Y290 PolarHBondContact O-N 3.04Å; Y290-P292 HydrophobicContact CE1-CB 4.03Å; Y290-P292 HydrophobicContact CE1-CG 4.26Å; Y290-L295 HydrophobicContact CE2-CD1 3.81Å; Y290-Y417 PolarHBondContact O-OH 2.94Å; Y290-D487 HydrophobicContact CD1-CB 4.49Å; Y290-D487 HydrophobicContact CE1-CB 3.88Å; Y290-F488 AromaticContact CD1-CD1 3.65Å; Y290-F488 HydrophobicContact CD1-CD1 3.65Å; Y290-F488 AromaticContact CD1-CE1 3.94Å; Y290-F488 HydrophobicContact CD1-CE1 3.94Å; Y290-F488 HydrophobicContact CD2-CD1 4.43Å; Y290-F488 HydrophobicContact CE1-CD1 4.02Å; Y290-F488 AromaticContact CG-CD1 3.86Å; Y290-F488 HydrophobicContact CG-CD1 3.86Å; Y290-F488 HydrophobicContact CG-CE1 4.05Å
291	N	82.1	Confident	78.4	Confident	13 Å²	13	59.3 Å²	59.3	7%	0.07	30%	0.295	C	S	.	.			trans	-119.6	96.3	178.9	-168.2	-8.2	0	0	0	112.3	I289 N293 L294 R413 H416 Y417	I289-N291 PolarHBondContact O-N 3.34Å; N291-N293 PolarHBondContact O-N 3.2Å; N291-N293 VanDerWaalsContact O-N 3.11Å; N291-N293 WeakPolarHBondContact OD1-CB 3.32Å; N291-N293 PolarHBondContact OD1-N 3.23Å; N291-N293 VanDerWaalsContact OD1-N 3.15Å; N291-L294 HydrophobicContact CB-CD1 3.98Å; N291-L294 HydrophobicContact CB-CG 4.07Å; N291-L294 PolarHBondContact O-N 3.4Å; N291-L294 VanDerWaalsContact O-N 3.1Å; N291-R413 PolarHBondContact ND2-O 3.12Å; N291-H416 PolarHBondContact OD1-CE1 3.45Å; N291-Y417 WeakPolarHBondContact CA-OH 3.39Å; N291-Y417 HydrophobicContact CB-CE2 4.29Å; N291-Y417 VanDerWaalsContact CB-OH 3.23Å; N291-Y417 WeakPolarHBondContact CB-OH 3.44Å
292	P	79.9	Confident	77.3	Confident	56 Å²	56	55.2 Å²	55.2	36%	0.364	28%	0.284	S	S	.	.	H	α-helix	trans	-62.5	-22.9	-179.5	25.3	-34.1	0	0	0	112.9	Y290 L294 L295 T296	Y290-P292 HydrophobicContact CE1-CB 4.03Å; Y290-P292 HydrophobicContact CE1-CG 4.26Å; P292-L294 VanDerWaalsContact C-N 3.26Å; P292-L294 PolarHBondContact O-N 3.1Å; P292-L295 PolarHBondContact O-N 3.37Å; P292-T296 PolarHBondContact O-N 3.34Å
293	N	79.2	Confident	76.1	Confident	59 Å²	59	56 Å²	56	32%	0.316	30%	0.296	S	S	.	.	H	α-helix	trans	-71.4	-19.5	179.6	-62.6	-43.2	0	0	0	112.8	N291 T296 R413	N291-N293 PolarHBondContact O-N 3.2Å; N291-N293 VanDerWaalsContact O-N 3.11Å; N291-N293 WeakPolarHBondContact OD1-CB 3.32Å; N291-N293 PolarHBondContact OD1-N 3.23Å; N291-N293 VanDerWaalsContact OD1-N 3.15Å; N293-T296 PolarHBondContact O-OG1 3.07Å; N293-R413 HydrophobicContact CB-CB 4.23Å; N293-R413 WeakPolarHBondContact O-CD 3.35Å; N293-R413 PolarHBondContact O-NH1 2.98Å
294	L	75.6	Confident	74.9	Confident	93 Å²	93	63.2 Å²	63.2	49%	0.487	33%	0.327	S	S	.	.	H	α-helix	trans	-73.8	-35.6	174.2	-67.5	177.2	0	0	0	111.3	N291 P292 A297 R413	N291-L294 HydrophobicContact CB-CD1 3.98Å; N291-L294 HydrophobicContact CB-CG 4.07Å; N291-L294 PolarHBondContact O-N 3.4Å; N291-L294 VanDerWaalsContact O-N 3.1Å; P292-L294 VanDerWaalsContact C-N 3.26Å; P292-L294 PolarHBondContact O-N 3.1Å; L294-A297 WeakPolarHBondContact O-CB 3.18Å; L294-A297 PolarHBondContact O-N 3.4Å; L294-R413 HydrophobicContact CD2-CB 4.37Å
295	L	69.6	Low	73.7	Confident	54 Å²	54	64.1 Å²	64.1	28%	0.283	33%	0.333	S	S	.	.	H	α-helix	trans	-71.9	-35.1	-178.4	-60.5	171.9	0	0	0	113.1	T258 D259 Y290 P292 A297 S298	T258-L295 HydrophobicContact CG2-CD1 4.37Å; T258-L295 WeakPolarHBondContact O-CD2 3.35Å; D259-L295 HydrophobicContact CB-CD2 4.14Å; Y290-L295 HydrophobicContact CE2-CD1 3.81Å; P292-L295 PolarHBondContact O-N 3.37Å; L295-A297 VanDerWaalsContact C-N 3.26Å; L295-S298 PolarHBondContact O-OG 2.89Å; L295-S298 VanDerWaalsContact O-OG 3.09Å
296	T	68.4	Low	72.5	Confident	52 Å²	52	65 Å²	65	32%	0.319	34%	0.34	S	S	.	.	H	α-helix	trans	-73.5	-21.8	174.1	52.8	0	0	0	0	112	P292 N293 S298 K299 F300	P292-T296 PolarHBondContact O-N 3.34Å; N293-T296 PolarHBondContact O-OG1 3.07Å; T296-S298 VanDerWaalsContact C-N 3.35Å; T296-S298 PolarHBondContact O-N 2.74Å; T296-K299 PolarHBondContact O-N 2.88Å; T296-F300 HydrophobicContact CG2-CE2 4.49Å; T296-F300 WeakPolarHBondContact O-CD2 3.49Å; T296-F300 PolarHBondContact O-N 3.06Å
297	A	66.5	Low	71.2	Confident	6 Å²	6	66.5 Å²	66.5	5%	0.05	36%	0.36	C	S	.	.	H	α-helix	trans	-60.3	-42.6	-177.8	0	0	0	0	0	112.5	L294 L295 R301 R413	L294-A297 WeakPolarHBondContact O-CB 3.18Å; L294-A297 PolarHBondContact O-N 3.4Å; L295-A297 VanDerWaalsContact C-N 3.26Å; A297-R301 VanDerWaalsContact O-CG 3.26Å; A297-R301 WeakPolarHBondContact O-CG 3.3Å; A297-R301 PolarHBondContact O-N 3.25Å; A297-R413 VanDerWaalsContact CB-CZ 3.41Å
298	S	64.8	Low	69.8	Low	69 Å²	69	69.7 Å²	69.7	48%	0.483	39%	0.393	S	S	.	.	H	α-helix	trans	-65.3	-43.4	176.9	58.4	0	0	0	0	111.6	L295 T296 F300 R301 A302	L295-S298 PolarHBondContact O-OG 2.89Å; L295-S298 VanDerWaalsContact O-OG 3.09Å; T296-S298 VanDerWaalsContact C-N 3.35Å; T296-S298 PolarHBondContact O-N 2.74Å; S298-F300 PolarHBondContact O-N 3.18Å; S298-R301 PolarHBondContact O-N 2.89Å; S298-A302 PolarHBondContact O-N 2.97Å
299	K	65.7	Low	68.4	Low	155 Å²	155	73.5 Å²	73.5	67%	0.674	41%	0.411	S	S	*	.	H	α-helix	trans	-62.5	-43.3	176.8	-63.1	-175.6	-179.4	-179.1	0	112.4	T296 A302 A303	T296-K299 PolarHBondContact O-N 2.88Å; K299-A302 PolarHBondContact O-N 2.9Å; K299-A303 WeakPolarHBondContact O-CB 3.48Å; K299-A303 PolarHBondContact O-N 2.87Å
300	F	64.6	Low	67.3	Low	138 Å²	138	80.4 Å²	80.4	61%	0.605	44%	0.44	S	S	*	.	H	α-helix	trans	-67.4	-35.1	176.7	-81.2	-67.9	0	0	0	112.8	T296 S298 K304	T296-F300 HydrophobicContact CG2-CE2 4.49Å; T296-F300 WeakPolarHBondContact O-CD2 3.49Å; T296-F300 PolarHBondContact O-N 3.06Å; S298-F300 PolarHBondContact O-N 3.18Å; F300-K304 WeakPolarHBondContact O-CB 3.38Å; F300-K304 PolarHBondContact O-N 2.86Å
301	R	67	Low	66.1	Low	59 Å²	59	83 Å²	83	22%	0.223	46%	0.46	C	S	.	.	H	α-helix	trans	-63.4	-50.1	173.2	-75.8	175.1	-159.1	171.2	5.2	111	A297 S298 A303 K304 H305 E346 H350	A297-R301 VanDerWaalsContact O-CG 3.26Å; A297-R301 WeakPolarHBondContact O-CG 3.3Å; A297-R301 PolarHBondContact O-N 3.25Å; S298-R301 PolarHBondContact O-N 2.89Å; R301-A303 PolarHBondContact O-N 2.94Å; R301-K304 PolarHBondContact O-N 3.18Å; R301-H305 PolarHBondContact O-N 2.84Å; R301-E346 WeakPolarHBondContact CB-OE2 3.4Å; R301-H350 PolarHBondContact NH2-CD2 3.06Å
302	A	64.5	Low	64.9	Low	48 Å²	48	90.9 Å²	90.9	40%	0.397	49%	0.49	S	S	.	.	H	α-helix	trans	-59.9	-41.6	176.7	0	0	0	0	0	112.9	S298 K299 H305 M306	S298-A302 PolarHBondContact O-N 2.97Å; K299-A302 PolarHBondContact O-N 2.9Å; A302-H305 PolarHBondContact O-N 3.48Å; A302-M306 PolarHBondContact O-N 2.87Å
303	A	64.9	Low	63.6	Low	53 Å²	53	94.4 Å²	94.4	44%	0.438	51%	0.506	S	S	.	.	H	α-helix	trans	-68.5	-36.3	178.9	0	0	0	0	0	113.2	K299 R301 H305 M306 A307	K299-A303 WeakPolarHBondContact O-CB 3.48Å; K299-A303 PolarHBondContact O-N 2.87Å; R301-A303 PolarHBondContact O-N 2.94Å; A303-H305 VanDerWaalsContact C-N 3.29Å; A303-H305 PolarHBondContact O-N 3.36Å; A303-M306 PolarHBondContact O-N 2.92Å; A303-A307 PolarHBondContact O-N 3.45Å
304	K	64.4	Low	62.5	Low	157 Å²	157	97.6 Å²	97.6	68%	0.683	53%	0.527	S	S	*	.	H	α-helix	trans	-62.8	-36.8	176.9	-173.6	-174.7	173.6	-162.9	0	111.9	F300 R301 M306 A307 G308	F300-K304 WeakPolarHBondContact O-CB 3.38Å; F300-K304 PolarHBondContact O-N 2.86Å; R301-K304 PolarHBondContact O-N 3.18Å; K304-M306 VanDerWaalsContact C-N 3.31Å; K304-M306 PolarHBondContact O-N 3.31Å; K304-A307 PolarHBondContact O-N 2.87Å; K304-G308 PolarHBondContact O-N 3.44Å
305	H	60.4	Low	61.5	Low	55 Å²	55	99.6 Å²	99.6	26%	0.255	54%	0.538	S	S	.	.	H	α-helix	trans	-63.6	-37	175.7	-179.9	-105.9	0	0	0	111.8	R301 A302 A303 E342	R301-H305 PolarHBondContact O-N 2.84Å; A302-H305 PolarHBondContact O-N 3.48Å; A303-H305 VanDerWaalsContact C-N 3.29Å; A303-H305 PolarHBondContact O-N 3.36Å; H305-E342 VanDerWaalsContact CD2-CD 3.46Å; H305-E342 IonicContact CD2-OE1 3.24Å; H305-E342 PolarHBondContact CD2-OE1 3.18Å; H305-E342 IonicContact CD2-OE2 2.62Å; H305-E342 PolarHBondContact CD2-OE2 3.49Å; H305-E342 IonicContact CE1-OE2 3.18Å; H305-E342 IonicContact NE2-OE1 2.82Å; H305-E342 IonicContact NE2-OE2 3.81Å; H305-E342 PolarHBondContact NE2-OE2 3.42Å
306	M	59.6	Low	61	Low	147 Å²	147	99.9 Å²	99.9	72%	0.724	55%	0.554	S	S	*	*	H	α-helix	trans	-72.8	-33.9	175.4	-63.9	-65	172.4	0	0	113	A302 A303 K304	A302-M306 PolarHBondContact O-N 2.87Å; A303-M306 PolarHBondContact O-N 2.92Å; K304-M306 VanDerWaalsContact C-N 3.31Å; K304-M306 PolarHBondContact O-N 3.31Å
307	A	60.6	Low	60.2	Low	83 Å²	83	104.3 Å²	104.3	69%	0.686	58%	0.584	S	S	*	*	H	α-helix	trans	-81.6	-12.9	-176.9	0	0	0	0	0	114.9	A303 K304 L309	A303-A307 PolarHBondContact O-N 3.45Å; K304-A307 PolarHBondContact O-N 2.87Å; A307-L309 PolarHBondContact O-N 3.32Å
308	G	58.4	Low	59.5	Low	67 Å²	67	109.2 Å²	109.2	69%	0.691	62%	0.618	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.7	-1.3	176.7	0	0	0	0	0	114.9	K304 K310	K304-G308 PolarHBondContact O-N 3.44Å; G308-K310 PolarHBondContact O-N 3.19Å
309	L	56.7	Low	59	Low	123 Å²	123	113.5 Å²	113.5	64%	0.644	64%	0.635	S	S	*	*			trans	-80.7	90.1	-178.7	-172.7	74.2	0	0	0	111.1	A307 V311	A307-L309 PolarHBondContact O-N 3.32Å; L309-V311 HydrophobicContact CD1-CG2 3.95Å; L309-V311 HydrophobicContact CD2-CG2 4.02Å; L309-V311 HydrophobicContact CG-CG2 3.75Å
310	K	59.1	Low	58.5	Low	165 Å²	165	112 Å²	112	72%	0.717	64%	0.635	S	S	*	*			trans	-93.8	99.4	158	-80.3	-174.4	178	-178	0	108.8	G308 Y312	G308-K310 PolarHBondContact O-N 3.19Å; K310-Y312 HydrophobicContact CB-CE2 4Å; K310-Y312 PolarHBondContact O-N 2.82Å
311	V	55.8	Low	58	Low	92 Å²	92	108.8 Å²	108.8	56%	0.558	63%	0.633	S	S	*	*			trans	-76.5	111.6	168.7	-174.9	0	0	0	0	107.3	L309	L309-V311 HydrophobicContact CD1-CG2 3.95Å; L309-V311 HydrophobicContact CD2-CG2 4.02Å; L309-V311 HydrophobicContact CG-CG2 3.75Å
312	Y	56.6	Low	57.5	Low	177 Å²	177	111.7 Å²	111.7	69%	0.694	66%	0.658	S	S	*	*			trans	-85.4	117.2	165.2	-68.7	-88.8	0	0	0	106.9	K310 V314	K310-Y312 HydrophobicContact CB-CE2 4Å; K310-Y312 PolarHBondContact O-N 2.82Å; Y312-V314 PolarHBondContact O-N 3.05Å; Y312-V314 VanDerWaalsContact O-N 3.13Å
313	N	52.4	Low	57	Low	130 Å²	130	111.5 Å²	111.5	70%	0.695	66%	0.661	S	S	*	*			trans	-68.2	106.8	167.6	-100	-10.3	0	0	0	107.4
314	V	57.7	Low	56.5	Low	127 Å²	127	113.6 Å²	113.6	77%	0.77	66%	0.662	S	S	*	*			trans	-89.1	-7.7	179.8	177.2	0	0	0	0	112.2	Y312	Y312-V314 PolarHBondContact O-N 3.05Å; Y312-V314 VanDerWaalsContact O-N 3.13Å
315	D	54.7	Low	56.2	Low	135 Å²	135	109.2 Å²	109.2	72%	0.722	65%	0.65	S	S	*	*	S	Bend	trans	-113.8	130.4	179.5	-64.4	-44.4	0	0	0	112.1
316	G	58.5	Low	56.1	Low	59 Å²	59	116.5 Å²	116.5	61%	0.608	68%	0.676	S	S	*	*			trans	-59.7	178.4	172	0	0	0	0	0	113	S318	G316-S318 PolarHBondContact O-N 3.02Å
317	P	51.4	Low	56.2	Low	145 Å²	145	112.4 Å²	112.4	94%	0.942	67%	0.666	S	S	*	*	S	Bend	trans	-69.8	95.5	-160.9	31.1	-34.6	0	0	0	110.9
318	S	52.7	Low	56.2	Low	109 Å²	109	113.6 Å²	113.6	76%	0.762	66%	0.658	S	S	*	*			trans	-139.5	145	169.3	-163.5	0	0	0	0	112.1	G316 N320	G316-S318 PolarHBondContact O-N 3.02Å; S318-N320 VanDerWaalsContact C-N 3.32Å; S318-N320 PolarHBondContact O-N 2.85Å
319	N	53.4	Low	56.3	Low	160 Å²	160	116 Å²	116	86%	0.856	65%	0.654	S	S	*	*	S	Bend	trans	-86.5	35.2	-141	-138.7	7.9	0	0	0	115.2
320	N	54.6	Low	56.6	Low	124 Å²	124	112.4 Å²	112.4	66%	0.663	64%	0.642	S	S	*	*			trans	-108.9	64.4	-174.1	-76.7	-13.6	0	0	0	113.4	S318 T322	S318-N320 VanDerWaalsContact C-N 3.32Å; S318-N320 PolarHBondContact O-N 2.85Å; N320-T322 PolarHBondContact O-N 2.82Å
321	A	55.2	Low	56.7	Low	69 Å²	69	107 Å²	107	57%	0.57	63%	0.628	S	S	*	*	H	α-helix	trans	-71.2	-25.3	-179.6	0	0	0	0	0	114.4
322	T	54.9	Low	57	Low	120 Å²	120	105.6 Å²	105.6	74%	0.736	63%	0.626	S	S	*	*	H	α-helix	trans	-80.3	-30.6	-172.8	47.3	0	0	0	0	114.2	N320	N320-T322 PolarHBondContact O-N 2.82Å
323	G	54.8	Low	57.1	Low	45 Å²	45	99.7 Å²	99.7	46%	0.464	61%	0.614	S	S	.	*	H	α-helix	trans	-74.2	-33.9	176	0	0	0	0	0	113.2	R326 A327	G323-R326 PolarHBondContact O-N 2.81Å; G323-A327 WeakPolarHBondContact O-CB 3.26Å; G323-A327 PolarHBondContact O-N 3.22Å
324	Q	55.3	Low	57.5	Low	97 Å²	97	103.2 Å²	103.2	45%	0.453	62%	0.617	S	S	.	*	H	α-helix	trans	-65.6	-39.1	177.4	-69.7	-176.5	-18	0	0	112	M328	Q324-M328 HydrophobicContact CB-CE 4.35Å; Q324-M328 WeakPolarHBondContact O-CB 3.35Å; Q324-M328 WeakPolarHBondContact O-CG 3.43Å; Q324-M328 PolarHBondContact O-N 3.35Å
325	S	56.5	Low	57.5	Low	64 Å²	64	104.3 Å²	104.3	45%	0.448	61%	0.608	S	S	.	*	H	α-helix	trans	-66	-41.4	175.4	-66.7	0	0	0	0	112.9	M328 I329	S325-M328 PolarHBondContact O-N 2.82Å; S325-I329 WeakPolarHBondContact O-CB 3.26Å; S325-I329 WeakPolarHBondContact O-CD1 3.46Å; S325-I329 WeakPolarHBondContact O-CG1 3.44Å; S325-I329 PolarHBondContact O-N 3.22Å
326	R	59	Low	57.7	Low	208 Å²	208	107.4 Å²	107.4	79%	0.785	61%	0.609	S	S	*	*	H	α-helix	trans	-68.4	-40.2	176.9	-99.9	-179.9	165.6	170.7	-3.9	112.6	G323 I329 A330	G323-R326 PolarHBondContact O-N 2.81Å; R326-I329 PolarHBondContact O-N 3Å; R326-A330 WeakPolarHBondContact O-CB 3.42Å; R326-A330 PolarHBondContact O-N 2.9Å
327	A	61.3	Low	57.5	Low	62 Å²	62	111 Å²	111	51%	0.512	61%	0.614	S	S	.	*	H	α-helix	trans	-65.8	-39.2	174.7	0	0	0	0	0	112	G323 A331	G323-A327 WeakPolarHBondContact O-CB 3.26Å; G323-A327 PolarHBondContact O-N 3.22Å; A327-A331 WeakPolarHBondContact O-CB 3.31Å; A327-A331 PolarHBondContact O-N 3.4Å
328	M	60	Low	57.9	Low	107 Å²	107	106.8 Å²	106.8	53%	0.527	59%	0.589	S	S	.	*	H	α-helix	trans	-64.9	-42.4	172.5	-83.1	-165.5	-101	0	0	112.6	Q324 S325 A331 A332	Q324-M328 HydrophobicContact CB-CE 4.35Å; Q324-M328 WeakPolarHBondContact O-CB 3.35Å; Q324-M328 WeakPolarHBondContact O-CG 3.43Å; Q324-M328 PolarHBondContact O-N 3.35Å; S325-M328 PolarHBondContact O-N 2.82Å; M328-A331 PolarHBondContact O-N 2.88Å; M328-A332 WeakPolarHBondContact O-CB 3.2Å; M328-A332 PolarHBondContact O-N 3.4Å
329	I	61.3	Low	58.4	Low	118 Å²	118	103.2 Å²	103.2	61%	0.605	56%	0.564	S	S	*	*	H	α-helix	trans	-66	-40.9	177.5	-68.5	162.9	0	0	0	110.9	S325 R326 A332 A333	S325-I329 WeakPolarHBondContact O-CB 3.26Å; S325-I329 WeakPolarHBondContact O-CD1 3.46Å; S325-I329 WeakPolarHBondContact O-CG1 3.44Å; S325-I329 PolarHBondContact O-N 3.22Å; R326-I329 PolarHBondContact O-N 3Å; I329-A332 PolarHBondContact O-N 3.5Å; I329-A333 WeakPolarHBondContact O-CB 3.48Å; I329-A333 PolarHBondContact O-N 3.21Å
330	A	63.2	Low	58.8	Low	48 Å²	48	102.5 Å²	102.5	40%	0.397	56%	0.555	S	S	.	*	H	α-helix	trans	-69.7	-37.3	176.5	0	0	0	0	0	112.9	R326 R334	R326-A330 WeakPolarHBondContact O-CB 3.42Å; R326-A330 PolarHBondContact O-N 2.9Å; A330-R334 WeakPolarHBondContact O-CG 3.49Å; A330-R334 PolarHBondContact O-N 3.11Å
331	A	61.7	Low	59.8	Low	51 Å²	51	100.9 Å²	100.9	42%	0.421	55%	0.546	S	S	.	.	H	α-helix	trans	-69.6	-38.4	174.2	0	0	0	0	0	112.2	A327 M328 R335	A327-A331 WeakPolarHBondContact O-CB 3.31Å; A327-A331 PolarHBondContact O-N 3.4Å; M328-A331 PolarHBondContact O-N 2.88Å; A331-R335 WeakPolarHBondContact O-CB 3.46Å; A331-R335 WeakPolarHBondContact O-CG 3.45Å; A331-R335 PolarHBondContact O-N 3.18Å
332	A	60.8	Low	60.6	Low	62 Å²	62	101.1 Å²	101.1	51%	0.512	54%	0.535	S	S	.	.	H	α-helix	trans	-66.3	-39.2	173.5	0	0	0	0	0	111.9	M328 I329 R335 R336	M328-A332 WeakPolarHBondContact O-CB 3.2Å; M328-A332 PolarHBondContact O-N 3.4Å; I329-A332 PolarHBondContact O-N 3.5Å; A332-R335 PolarHBondContact O-N 3.34Å; A332-R336 PolarHBondContact O-N 3.13Å
333	A	60.2	Low	61.5	Low	53 Å²	53	99.5 Å²	99.5	44%	0.438	52%	0.522	S	S	.	.	H	α-helix	trans	-63.6	-47.9	174.5	0	0	0	0	0	112.1	I329 R335 R336	I329-A333 WeakPolarHBondContact O-CB 3.48Å; I329-A333 PolarHBondContact O-N 3.21Å; A333-R335 VanDerWaalsContact C-N 3.29Å; A333-R335 PolarHBondContact O-N 2.94Å; A333-R336 WeakPolarHBondContact O-CB 3.46Å; A333-R336 PolarHBondContact O-N 3.5Å; A333-R336 VanDerWaalsContact O-N 3.16Å
334	R	61	Low	62.8	Low	204 Å²	204	104.1 Å²	104.1	77%	0.77	53%	0.526	S	S	*	.	H	α-helix	trans	-65.5	-28.5	177	-71.4	-179.4	-179.8	171.8	0.6	113.6	A330 S338	A330-R334 WeakPolarHBondContact O-CG 3.49Å; A330-R334 PolarHBondContact O-N 3.11Å; R334-S338 PolarHBondContact O-N 3.19Å
335	R	56.3	Low	64.1	Low	150 Å²	150	105.9 Å²	105.9	57%	0.566	53%	0.53	S	S	*	.	H	α-helix	trans	-80.1	-24.2	173.6	-76.6	-168.7	-179.3	-152.6	2.9	113.6	A331 A332 A333 D337 S338 S339	A331-R335 WeakPolarHBondContact O-CB 3.46Å; A331-R335 WeakPolarHBondContact O-CG 3.45Å; A331-R335 PolarHBondContact O-N 3.18Å; A332-R335 PolarHBondContact O-N 3.34Å; A333-R335 VanDerWaalsContact C-N 3.29Å; A333-R335 PolarHBondContact O-N 2.94Å; R335-D337 VanDerWaalsContact C-N 3.26Å; R335-D337 PolarHBondContact O-N 3.5Å; R335-S338 PolarHBondContact O-N 2.81Å; R335-S338 PolarHBondContact O-OG 3.37Å; R335-S339 WeakPolarHBondContact O-CB 3.31Å; R335-S339 PolarHBondContact O-N 2.62Å
336	R	59.8	Low	65.3	Low	200 Å²	200	105.1 Å²	105.1	76%	0.755	52%	0.519	S	S	*	.	H	α-helix	trans	-61.8	-38.5	172.4	-166.3	175.9	178	179.1	-2	110.8	A332 A333 S339	A332-R336 PolarHBondContact O-N 3.13Å; A333-R336 WeakPolarHBondContact O-CB 3.46Å; A333-R336 PolarHBondContact O-N 3.5Å; A333-R336 VanDerWaalsContact O-N 3.16Å; R336-S339 PolarHBondContact O-N 3.15Å; R336-S339 PolarHBondContact O-OG 3.16Å
337	D	54.9	Low	66.4	Low	135 Å²	135	100.4 Å²	100.4	72%	0.722	51%	0.506	S	S	*	.	H	α-helix	trans	-73.9	-31.4	175.8	-62.7	-28.5	0	0	0	112.8	R335	R335-D337 VanDerWaalsContact C-N 3.26Å; R335-D337 PolarHBondContact O-N 3.5Å
338	S	59	Low	67.7	Low	57 Å²	57	98.5 Å²	98.5	40%	0.399	49%	0.49	S	S	.	.	H	α-helix	trans	-77.2	-21.2	172.8	88.2	0	0	0	0	113.8	R334 R335 H340 N341 E342	R334-S338 PolarHBondContact O-N 3.19Å; R335-S338 PolarHBondContact O-N 2.81Å; R335-S338 PolarHBondContact O-OG 3.37Å; S338-H340 VanDerWaalsContact C-N 3.29Å; S338-H340 PolarHBondContact O-N 3.46Å; S338-N341 PolarHBondContact O-N 3.04Å; S338-E342 PolarHBondContact O-N 3.48Å
339	S	62.4	Low	69	Low	34 Å²	34	98.8 Å²	98.8	24%	0.238	49%	0.49	C	S	.	.	H	α-helix	trans	-65.2	-28.7	-176.5	74.6	0	0	0	0	113.7	R335 R336 E342 L343	R335-S339 WeakPolarHBondContact O-CB 3.31Å; R335-S339 PolarHBondContact O-N 2.62Å; R336-S339 PolarHBondContact O-N 3.15Å; R336-S339 PolarHBondContact O-OG 3.16Å; S339-E342 PolarHBondContact O-N 3.48Å; S339-L343 WeakPolarHBondContact O-CG 3.3Å; S339-L343 PolarHBondContact O-N 3.44Å
340	H	63	Low	70.2	Confident	144 Å²	144	95.1 Å²	95.1	67%	0.667	47%	0.471	S	S	*	.	H	α-helix	trans	-66.4	-40.1	175.5	-176.6	-86.6	0	0	0	111.9	S338 Y344	S338-H340 VanDerWaalsContact C-N 3.29Å; S338-H340 PolarHBondContact O-N 3.46Å; H340-Y344 PolarHBondContact O-N 3.21Å
341	N	74.2	Confident	71.5	Confident	91 Å²	91	97.4 Å²	97.4	49%	0.487	47%	0.473	S	S	.	.	H	α-helix	trans	-69	-36.9	176.6	-122.2	5.5	0	0	0	111.3	S338 Y344 Y345	S338-N341 PolarHBondContact O-N 3.04Å; N341-Y344 WeakPolarHBondContact O-CB 3.48Å; N341-Y344 PolarHBondContact O-N 3.18Å; N341-Y345 HydrophobicContact CB-CE2 4.39Å; N341-Y345 WeakPolarHBondContact O-CD2 3.22Å; N341-Y345 PolarHBondContact O-N 3.2Å; N341-Y345 VanDerWaalsContact O-N 3.1Å
342	E	72.6	Confident	72.9	Confident	73 Å²	73	103.6 Å²	103.6	34%	0.341	49%	0.485	S	S	.	.	H	α-helix	trans	-66.5	-41.6	178.1	-168.9	171.6	179	0	0	112.6	H305 S338 S339 Y344 Y345 E346	H305-E342 VanDerWaalsContact CD2-CD 3.46Å; H305-E342 IonicContact CD2-OE1 3.24Å; H305-E342 PolarHBondContact CD2-OE1 3.18Å; H305-E342 IonicContact CD2-OE2 2.62Å; H305-E342 PolarHBondContact CD2-OE2 3.49Å; H305-E342 IonicContact CE1-OE2 3.18Å; H305-E342 IonicContact NE2-OE1 2.82Å; H305-E342 IonicContact NE2-OE2 3.81Å; H305-E342 PolarHBondContact NE2-OE2 3.42Å; S338-E342 PolarHBondContact O-N 3.48Å; S339-E342 PolarHBondContact O-N 3.48Å; E342-Y344 VanDerWaalsContact C-N 3.31Å; E342-Y344 PolarHBondContact O-N 3.33Å; E342-Y345 PolarHBondContact O-N 3.05Å; E342-E346 WeakPolarHBondContact O-CG 3.4Å; E342-E346 PolarHBondContact O-N 3.38Å
343	L	73.9	Confident	74.4	Confident	86 Å²	86	107 Å²	107	45%	0.45	49%	0.485	S	S	.	.	H	α-helix	trans	-58.9	-42.2	173.9	-73.8	172	0	0	0	112	S339 E346 E347	S339-L343 WeakPolarHBondContact O-CG 3.3Å; S339-L343 PolarHBondContact O-N 3.44Å; L343-E346 PolarHBondContact O-N 2.94Å; L343-E347 WeakPolarHBondContact O-CB 3.31Å; L343-E347 PolarHBondContact O-N 3.45Å
344	Y	81.6	Confident	76	Confident	142 Å²	142	105.9 Å²	105.9	56%	0.557	47%	0.473	S	S	*	.	H	α-helix	trans	-59.7	-47.8	174.6	170	-98.6	0	0	0	111.9	H340 N341 E342 E346 E347 A348	H340-Y344 PolarHBondContact O-N 3.21Å; N341-Y344 WeakPolarHBondContact O-CB 3.48Å; N341-Y344 PolarHBondContact O-N 3.18Å; E342-Y344 VanDerWaalsContact C-N 3.31Å; E342-Y344 PolarHBondContact O-N 3.33Å; Y344-E346 PolarHBondContact O-N 3.32Å; Y344-E347 PolarHBondContact O-N 3.28Å; Y344-A348 WeakPolarHBondContact O-CB 2.95Å; Y344-A348 PolarHBondContact O-N 2.99Å
345	Y	83.3	Confident	77.6	Confident	135 Å²	135	102.4 Å²	102.4	53%	0.529	46%	0.463	S	S	.	.	H	α-helix	trans	-66.1	-38.2	178.6	-70.7	-63.2	0	0	0	112.5	N341 E342 A348 E349	N341-Y345 HydrophobicContact CB-CE2 4.39Å; N341-Y345 WeakPolarHBondContact O-CD2 3.22Å; N341-Y345 PolarHBondContact O-N 3.2Å; N341-Y345 VanDerWaalsContact O-N 3.1Å; E342-Y345 PolarHBondContact O-N 3.05Å; Y345-A348 PolarHBondContact O-N 3.5Å; Y345-E349 WeakPolarHBondContact O-CB 3.46Å; Y345-E349 WeakPolarHBondContact O-CG 3.41Å; Y345-E349 PolarHBondContact O-N 3.24Å
346	E	81.4	Confident	79.5	Confident	47 Å²	47	101.2 Å²	101.2	22%	0.22	46%	0.462	C	S	.	.	H	α-helix	trans	-64.7	-39.4	175.1	-75	-161.8	150.7	0	0	112.7	R301 E342 L343 Y344 E349 H350	R301-E346 WeakPolarHBondContact CB-OE2 3.4Å; E342-E346 WeakPolarHBondContact O-CG 3.4Å; E342-E346 PolarHBondContact O-N 3.38Å; L343-E346 PolarHBondContact O-N 2.94Å; Y344-E346 PolarHBondContact O-N 3.32Å; E346-E349 PolarHBondContact O-N 3.29Å; E346-H350 VanDerWaalsContact O-CB 3.29Å; E346-H350 WeakPolarHBondContact O-CB 3.43Å; E346-H350 PolarHBondContact O-N 2.78Å
347	E	83.4	Confident	81.1	Confident	109 Å²	109	95 Å²	95	51%	0.509	44%	0.439	S	S	.	.	H	α-helix	trans	-65	-47.3	174.3	-175.3	160.5	-140.6	0	0	110.7	L343 Y344 E349 H350 E351	L343-E347 WeakPolarHBondContact O-CB 3.31Å; L343-E347 PolarHBondContact O-N 3.45Å; Y344-E347 PolarHBondContact O-N 3.28Å; E347-E349 VanDerWaalsContact C-N 3.34Å; E347-E349 PolarHBondContact O-N 3.09Å; E347-H350 CarbonylContact O-C 3.59Å; E347-H350 WeakPolarHBondContact O-CA 3.21Å; E347-H350 WeakPolarHBondContact O-CB 3.44Å; E347-H350 PolarHBondContact O-N 2.99Å; E347-H350 VanDerWaalsContact O-N 3.09Å; E347-E351 WeakPolarHBondContact O-CG 3.36Å; E347-E351 PolarHBondContact O-N 3.37Å
348	A	87.1	Confident	83	Confident	22 Å²	22	93.1 Å²	93.1	18%	0.182	42%	0.424	C	S	.	.	H	α-helix	trans	-59.7	-41.3	174.6	0	0	0	0	0	112.4	Y344 Y345 E351 R352	Y344-A348 WeakPolarHBondContact O-CB 2.95Å; Y344-A348 PolarHBondContact O-N 2.99Å; Y345-A348 PolarHBondContact O-N 3.5Å; A348-E351 PolarHBondContact O-N 2.88Å; A348-R352 WeakPolarHBondContact O-CB 3.4Å; A348-R352 WeakPolarHBondContact O-CG 3.43Å; A348-R352 PolarHBondContact O-N 3.48Å
349	E	87.8	Confident	84.8	Confident	114 Å²	114	93.2 Å²	93.2	53%	0.533	43%	0.428	S	S	.	.	H	α-helix	trans	-66	-37.8	173.6	-79.9	-167.7	175.1	0	0	112.6	Y345 E346 E347 R353	Y345-E349 WeakPolarHBondContact O-CB 3.46Å; Y345-E349 WeakPolarHBondContact O-CG 3.41Å; Y345-E349 PolarHBondContact O-N 3.24Å; E346-E349 PolarHBondContact O-N 3.29Å; E347-E349 VanDerWaalsContact C-N 3.34Å; E347-E349 PolarHBondContact O-N 3.09Å; E349-R353 WeakPolarHBondContact O-CB 3.45Å; E349-R353 VanDerWaalsContact O-CG 3.31Å; E349-R353 WeakPolarHBondContact O-CG 3.4Å; E349-R353 PolarHBondContact O-N 3.38Å; E349-R353 PolarHBondContact O-NE 3.38Å
350	H	87.2	Confident	86.4	Confident	41 Å²	41	97.6 Å²	97.6	19%	0.19	44%	0.439	C	S	.	.	H	α-helix	trans	-63.7	-48.7	174.3	-176.8	69.1	0	0	0	111.1	R301 E346 E347 R352 R353 V354 T411	R301-H350 PolarHBondContact NH2-CD2 3.06Å; E346-H350 VanDerWaalsContact O-CB 3.29Å; E346-H350 WeakPolarHBondContact O-CB 3.43Å; E346-H350 PolarHBondContact O-N 2.78Å; E347-H350 CarbonylContact O-C 3.59Å; E347-H350 WeakPolarHBondContact O-CA 3.21Å; E347-H350 WeakPolarHBondContact O-CB 3.44Å; E347-H350 PolarHBondContact O-N 2.99Å; E347-H350 VanDerWaalsContact O-N 3.09Å; H350-R352 VanDerWaalsContact C-N 3.35Å; H350-R352 PolarHBondContact O-N 2.92Å; H350-R353 WeakPolarHBondContact O-CA 3.47Å; H350-R353 WeakPolarHBondContact O-CB 3.15Å; H350-R353 PolarHBondContact O-N 3.02Å; H350-R353 VanDerWaalsContact O-N 3.1Å; H350-V354 WeakPolarHBondContact O-CG2 3.49Å; H350-V354 PolarHBondContact O-N 3.43Å; H350-T411 PolarHBondContact CE1-O 3.31Å
351	E	89.8	Confident	88	Confident	95 Å²	95	90.8 Å²	90.8	44%	0.444	41%	0.408	S	S	.	.	H	α-helix	trans	-58.3	-45.3	174.8	-73.8	-165.5	177.5	0	0	112.2	E347 A348 R353 V354 K355	E347-E351 WeakPolarHBondContact O-CG 3.36Å; E347-E351 PolarHBondContact O-N 3.37Å; A348-E351 PolarHBondContact O-N 2.88Å; E351-R353 VanDerWaalsContact C-N 3.28Å; E351-R353 PolarHBondContact O-N 2.9Å; E351-V354 PolarHBondContact O-N 2.85Å; E351-K355 WeakPolarHBondContact O-CB 3.49Å; E351-K355 WeakPolarHBondContact O-CG 3.48Å; E351-K355 PolarHBondContact O-N 3.15Å; E351-K355 IonicContact OE2-NZ 3.38Å; E351-K355 PolarHBondContact OE2-NZ 3.43Å
352	R	92.4	Very high	89	Confident	182 Å²	182	88.1 Å²	88.1	69%	0.687	40%	0.395	S	S	*	.	H	α-helix	trans	-58.4	-41.4	175.3	-76.1	172.2	-178.1	-169.9	1.3	111.1	A348 H350 K356	A348-R352 WeakPolarHBondContact O-CB 3.4Å; A348-R352 WeakPolarHBondContact O-CG 3.43Å; A348-R352 PolarHBondContact O-N 3.48Å; H350-R352 VanDerWaalsContact C-N 3.35Å; H350-R352 PolarHBondContact O-N 2.92Å; R352-K356 VanDerWaalsContact O-CB 3.25Å; R352-K356 WeakPolarHBondContact O-CB 3.16Å; R352-K356 PolarHBondContact O-N 3.13Å
353	R	92.3	Very high	90.1	Very high	133 Å²	133	88 Å²	88	50%	0.502	40%	0.399	S	S	.	.	H	α-helix	trans	-64.2	-45.2	174.9	-77.2	-178.3	-69.1	-175.4	-3	111.7	E349 H350 E351 K356 R357 T411	E349-R353 WeakPolarHBondContact O-CB 3.45Å; E349-R353 VanDerWaalsContact O-CG 3.31Å; E349-R353 WeakPolarHBondContact O-CG 3.4Å; E349-R353 PolarHBondContact O-N 3.38Å; E349-R353 PolarHBondContact O-NE 3.38Å; H350-R353 WeakPolarHBondContact O-CA 3.47Å; H350-R353 WeakPolarHBondContact O-CB 3.15Å; H350-R353 PolarHBondContact O-N 3.02Å; H350-R353 VanDerWaalsContact O-N 3.1Å; E351-R353 VanDerWaalsContact C-N 3.28Å; E351-R353 PolarHBondContact O-N 2.9Å; R353-K356 PolarHBondContact O-N 3.38Å; R353-R357 WeakPolarHBondContact O-CB 3.28Å; R353-R357 VanDerWaalsContact O-CG 3.23Å; R353-R357 WeakPolarHBondContact O-CG 3.4Å; R353-R357 PolarHBondContact O-N 2.82Å; R353-T411 HydrophobicContact CB-CG2 4.47Å
354	V	92.6	Very high	91.2	Very high	30 Å²	30	84.5 Å²	84.5	18%	0.182	38%	0.383	C	S	.	.	H	α-helix	trans	-59.9	-50.9	176.5	173.8	0	0	0	0	110.3	H350 E351 K356 R357 K358 Y408 T411 T412	H350-V354 WeakPolarHBondContact O-CG2 3.49Å; H350-V354 PolarHBondContact O-N 3.43Å; E351-V354 PolarHBondContact O-N 2.85Å; V354-K356 VanDerWaalsContact C-N 3.35Å; V354-K356 PolarHBondContact O-N 3.49Å; V354-R357 PolarHBondContact O-N 3.48Å; V354-R357 VanDerWaalsContact O-N 3.12Å; V354-K358 WeakPolarHBondContact O-CB 3.29Å; V354-K358 PolarHBondContact O-N 3.09Å; V354-Y408 HydrophobicContact CG1-CE2 4.14Å; V354-T411 HydrophobicContact CG2-CG2 3.92Å; V354-T412 HydrophobicContact CG1-CG2 4.18Å; V354-T412 HydrophobicContact CG2-CG2 4.46Å
355	K	94.8	Very high	91.9	Very high	131 Å²	131	77.8 Å²	77.8	57%	0.57	36%	0.356	S	S	*	.	H	α-helix	trans	-56.9	-45.1	177.4	-71.8	171.4	-178	164.1	0	111.8	E351 R357 K358 A359	E351-K355 WeakPolarHBondContact O-CB 3.49Å; E351-K355 WeakPolarHBondContact O-CG 3.48Å; E351-K355 PolarHBondContact O-N 3.15Å; E351-K355 IonicContact OE2-NZ 3.38Å; E351-K355 PolarHBondContact OE2-NZ 3.43Å; K355-R357 PolarHBondContact O-N 3.34Å; K355-K358 WeakPolarHBondContact O-CB 3.38Å; K355-K358 PolarHBondContact O-N 2.9Å; K355-A359 PolarHBondContact O-N 3.09Å
356	K	96	Very high	92.5	Very high	124 Å²	124	74.7 Å²	74.7	54%	0.539	35%	0.347	S	S	.	.	H	α-helix	trans	-63.6	-39.3	176.1	-177.5	173	-177.1	169.3	0	112.9	R352 R353 V354 R360	R352-K356 VanDerWaalsContact O-CB 3.25Å; R352-K356 WeakPolarHBondContact O-CB 3.16Å; R352-K356 PolarHBondContact O-N 3.13Å; R353-K356 PolarHBondContact O-N 3.38Å; V354-K356 VanDerWaalsContact C-N 3.35Å; V354-K356 PolarHBondContact O-N 3.49Å; K356-R360 VanDerWaalsContact O-CG 3.3Å; K356-R360 WeakPolarHBondContact O-CG 3.37Å; K356-R360 PolarHBondContact O-N 2.75Å
357	R	94.6	Very high	93.1	Very high	71 Å²	71	78.5 Å²	78.5	27%	0.268	36%	0.364	S	S	.	.	H	α-helix	trans	-71.1	-40.3	176.6	-68.2	-64.8	-175.1	-149.8	-6.6	111.4	R353 V354 K355 R360 L361 Y408	R353-R357 WeakPolarHBondContact O-CB 3.28Å; R353-R357 VanDerWaalsContact O-CG 3.23Å; R353-R357 WeakPolarHBondContact O-CG 3.4Å; R353-R357 PolarHBondContact O-N 2.82Å; V354-R357 PolarHBondContact O-N 3.48Å; V354-R357 VanDerWaalsContact O-N 3.12Å; K355-R357 PolarHBondContact O-N 3.34Å; R357-R360 PolarHBondContact O-N 3.34Å; R357-L361 WeakPolarHBondContact O-CB 3.42Å; R357-L361 PolarHBondContact O-N 2.82Å; R357-Y408 HydrophobicContact CB-CD2 4.01Å
358	K	94.9	Very high	93.5	Very high	95 Å²	95	73.5 Å²	73.5	41%	0.413	34%	0.341	S	S	.	.	H	α-helix	trans	-56.6	-52.9	174.2	-178.3	176	-177.6	179.2	0	110.9	V354 K355 R360 L361 V362 Y408 L445	V354-K358 WeakPolarHBondContact O-CB 3.29Å; V354-K358 PolarHBondContact O-N 3.09Å; K355-K358 WeakPolarHBondContact O-CB 3.38Å; K355-K358 PolarHBondContact O-N 2.9Å; K358-R360 VanDerWaalsContact C-N 3.32Å; K358-R360 PolarHBondContact O-N 2.74Å; K358-L361 WeakPolarHBondContact O-CB 3.38Å; K358-L361 PolarHBondContact O-N 2.85Å; K358-L361 VanDerWaalsContact O-N 3.1Å; K358-V362 WeakPolarHBondContact O-CG2 3.4Å; K358-V362 PolarHBondContact O-N 3.5Å; K358-Y408 HydrophobicContact CB-CD2 4.28Å; K358-Y408 HydrophobicContact CB-CE2 3.88Å; K358-Y408 HydrophobicContact CG-CE2 4.5Å; K358-L445 HydrophobicContact CD-CD2 4.36Å; K358-L445 HydrophobicContact CG-CD1 4.47Å; K358-L445 HydrophobicContact CG-CD2 3.89Å
359	A	95.7	Very high	93.8	Very high	58 Å²	58	73 Å²	73	48%	0.479	34%	0.335	S	S	.	.	H	α-helix	trans	-57.7	-43.8	178.8	0	0	0	0	0	112.5	K355 L361 V362 V363	K355-A359 PolarHBondContact O-N 3.09Å; A359-L361 VanDerWaalsContact C-N 3.33Å; A359-L361 PolarHBondContact O-N 2.62Å; A359-V362 PolarHBondContact O-N 3.4Å; A359-V363 WeakPolarHBondContact O-CG2 3.49Å; A359-V363 PolarHBondContact O-N 3.35Å; A359-V363 VanDerWaalsContact O-N 3.12Å
360	R	95.8	Very high	93.9	Very high	127 Å²	127	71.2 Å²	71.2	48%	0.479	33%	0.328	S	S	.	.	H	α-helix	trans	-64.8	-36	176.6	-71.1	172.3	-179.7	-151.6	-4.2	113.3	K356 R357 K358 A364	K356-R360 VanDerWaalsContact O-CG 3.3Å; K356-R360 WeakPolarHBondContact O-CG 3.37Å; K356-R360 PolarHBondContact O-N 2.75Å; R357-R360 PolarHBondContact O-N 3.34Å; K358-R360 VanDerWaalsContact C-N 3.32Å; K358-R360 PolarHBondContact O-N 2.74Å; R360-A364 WeakPolarHBondContact O-CB 3.2Å; R360-A364 PolarHBondContact O-N 3.48Å; R360-A364 VanDerWaalsContact O-N 3.13Å
361	L	96.1	Very high	94	Very high	0 Å²	0	73.9 Å²	73.9	0%	0	34%	0.341	C	S	.	.	H	α-helix	trans	-68	-45.3	176.4	173	59.2	0	0	0	110.8	R357 K358 A359 V363 A364 V365 A404 L405 Y408 L441 L445	R357-L361 WeakPolarHBondContact O-CB 3.42Å; R357-L361 PolarHBondContact O-N 2.82Å; K358-L361 WeakPolarHBondContact O-CB 3.38Å; K358-L361 PolarHBondContact O-N 2.85Å; K358-L361 VanDerWaalsContact O-N 3.1Å; A359-L361 VanDerWaalsContact C-N 3.33Å; A359-L361 PolarHBondContact O-N 2.62Å; L361-V363 PolarHBondContact O-N 3.17Å; L361-A364 PolarHBondContact O-N 3.45Å; L361-V365 HydrophobicContact CD1-CG2 3.82Å; L361-V365 WeakPolarHBondContact O-CG2 3.36Å; L361-V365 PolarHBondContact O-N 3.41Å; L361-A404 HydrophobicContact CB-CB 4.45Å; L361-A404 HydrophobicContact CD1-CB 4.23Å; L361-L405 HydrophobicContact CD1-CB 3.8Å; L361-L405 HydrophobicContact CD1-CD1 4.02Å; L361-L405 HydrophobicContact CD2-CD1 3.83Å; L361-Y408 HydrophobicContact CD2-CD1 3.87Å; L361-Y408 HydrophobicContact CD2-CG 3.86Å; L361-L441 HydrophobicContact CD1-CD2 4.07Å; L361-L441 HydrophobicContact CD2-CD2 3.83Å; L361-L441 HydrophobicContact CG-CD2 3.65Å; L361-L445 HydrophobicContact CD2-CD2 4.21Å
362	V	96.2	Very high	93.8	Very high	35 Å²	35	69.8 Å²	69.8	21%	0.212	32%	0.322	C	S	.	.	H	α-helix	trans	-55.6	-52.9	177.4	172.4	0	0	0	0	110.6	K358 A359 A364 V365 E366 L441 L445	K358-V362 WeakPolarHBondContact O-CG2 3.4Å; K358-V362 PolarHBondContact O-N 3.5Å; A359-V362 PolarHBondContact O-N 3.4Å; V362-A364 PolarHBondContact O-N 3.18Å; V362-V365 PolarHBondContact O-N 2.83Å; V362-E366 HydrophobicContact CG1-CG 4.45Å; V362-E366 WeakPolarHBondContact O-CG 3.49Å; V362-E366 PolarHBondContact O-N 3.23Å; V362-L441 HydrophobicContact CB-CD1 4.33Å; V362-L441 HydrophobicContact CG2-CD1 3.94Å; V362-L445 HydrophobicContact CG2-CD1 4.34Å
363	V	96.4	Very high	93.4	Very high	70 Å²	70	66.8 Å²	66.8	42%	0.424	32%	0.316	S	S	.	.	H	α-helix	trans	-59.9	-46.6	179.4	175	0	0	0	0	111.8	A359 L361 V365 E366 E367	A359-V363 WeakPolarHBondContact O-CG2 3.49Å; A359-V363 PolarHBondContact O-N 3.35Å; A359-V363 VanDerWaalsContact O-N 3.12Å; L361-V363 PolarHBondContact O-N 3.17Å; V363-V365 VanDerWaalsContact C-N 3.29Å; V363-V365 PolarHBondContact O-N 3.41Å; V363-E366 PolarHBondContact O-N 3.2Å; V363-E367 HydrophobicContact CG1-CG 4.42Å; V363-E367 WeakPolarHBondContact O-CG 3.29Å; V363-E367 PolarHBondContact O-N 3.42Å
364	A	96	Very high	93	Very high	14 Å²	14	68 Å²	68	12%	0.116	32%	0.321	C	S	.	.	H	α-helix	trans	-63.7	-33.6	-179.1	0	0	0	0	0	113.1	R360 L361 V362 A368 A404	R360-A364 WeakPolarHBondContact O-CB 3.2Å; R360-A364 PolarHBondContact O-N 3.48Å; R360-A364 VanDerWaalsContact O-N 3.13Å; L361-A364 PolarHBondContact O-N 3.45Å; V362-A364 PolarHBondContact O-N 3.18Å; A364-A368 WeakPolarHBondContact O-CB 3.4Å; A364-A368 PolarHBondContact O-N 3.36Å; A364-A404 HydrophobicContact CB-CB 3.96Å
365	V	96	Very high	92.4	Very high	0 Å²	0	68.6 Å²	68.6	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-76.2	-40.4	176	176.4	0	0	0	0	111.1	L361 V362 V363 E367 A368 F369 M401 P437 F440 L441	L361-V365 HydrophobicContact CD1-CG2 3.82Å; L361-V365 WeakPolarHBondContact O-CG2 3.36Å; L361-V365 PolarHBondContact O-N 3.41Å; V362-V365 PolarHBondContact O-N 2.83Å; V363-V365 VanDerWaalsContact C-N 3.29Å; V363-V365 PolarHBondContact O-N 3.41Å; V365-E367 VanDerWaalsContact C-N 3.34Å; V365-E367 PolarHBondContact O-N 3.25Å; V365-A368 PolarHBondContact O-N 3.03Å; V365-F369 HydrophobicContact CG1-CD2 3.68Å; V365-F369 HydrophobicContact CG1-CE2 3.68Å; V365-F369 WeakPolarHBondContact O-CD2 3.45Å; V365-F369 PolarHBondContact O-N 2.7Å; V365-M401 HydrophobicContact CG1-CE 4.31Å; V365-M401 HydrophobicContact CG2-CB 4.05Å; V365-M401 HydrophobicContact CG2-CE 4.22Å; V365-M401 HydrophobicContact CG2-SD 3.97Å; V365-P437 HydrophobicContact CG1-CB 3.97Å; V365-F440 HydrophobicContact CG1-CD1 3.72Å; V365-F440 HydrophobicContact CG1-CE1 4.28Å; V365-F440 HydrophobicContact CG2-CD1 4.29Å; V365-F440 HydrophobicContact CG2-CE1 4.13Å; V365-L441 HydrophobicContact CB-CD1 4.15Å; V365-L441 HydrophobicContact CB-CD2 4.35Å; V365-L441 HydrophobicContact CB-CG 4.31Å; V365-L441 HydrophobicContact CG1-CD1 4.32Å; V365-L441 HydrophobicContact CG1-CG 4.16Å; V365-L441 HydrophobicContact CG2-CD1 4.47Å; V365-L441 HydrophobicContact CG2-CD2 3.81Å; V365-L441 HydrophobicContact CG2-CG 4.28Å
366	E	95.2	Very high	91.5	Very high	71 Å²	71	66.3 Å²	66.3	33%	0.332	31%	0.314	S	S	.	.	H	α-helix	trans	-58.5	-46.3	174.5	-73.5	173.2	168.5	0	0	111.2	V362 V363 A368 F369 I370 P437	V362-E366 HydrophobicContact CG1-CG 4.45Å; V362-E366 WeakPolarHBondContact O-CG 3.49Å; V362-E366 PolarHBondContact O-N 3.23Å; V363-E366 PolarHBondContact O-N 3.2Å; E366-A368 VanDerWaalsContact C-N 3.35Å; E366-A368 PolarHBondContact O-N 3.11Å; E366-F369 PolarHBondContact O-N 3.27Å; E366-I370 VanDerWaalsContact O-CG1 3.27Å; E366-I370 WeakPolarHBondContact O-CG1 3.06Å; E366-I370 PolarHBondContact O-N 3.15Å; E366-P437 HydrophobicContact CG-CB 4Å; E366-P437 HydrophobicContact CG-CG 4.31Å
367	E	94.6	Very high	90.7	Very high	127 Å²	127	64.1 Å²	64.1	59%	0.593	31%	0.31	S	S	*	.	H	α-helix	trans	-59.4	-42.6	175	-73	175.3	176.8	0	0	112.4	V363 V365 I370 H371	V363-E367 HydrophobicContact CG1-CG 4.42Å; V363-E367 WeakPolarHBondContact O-CG 3.29Å; V363-E367 PolarHBondContact O-N 3.42Å; V365-E367 VanDerWaalsContact C-N 3.34Å; V365-E367 PolarHBondContact O-N 3.25Å; E367-I370 PolarHBondContact O-N 3.3Å; E367-H371 PolarHBondContact O-N 3.1Å
368	A	92.7	Very high	89.8	Confident	3 Å²	3	66 Å²	66	3%	0.025	32%	0.322	C	S	.	.	H	α-helix	trans	-67.2	-37.7	179.6	0	0	0	0	0	113.2	A364 V365 E366 H371 I372 I397 S400 M401	A364-A368 WeakPolarHBondContact O-CB 3.4Å; A364-A368 PolarHBondContact O-N 3.36Å; V365-A368 PolarHBondContact O-N 3.03Å; E366-A368 VanDerWaalsContact C-N 3.35Å; E366-A368 PolarHBondContact O-N 3.11Å; A368-H371 VanDerWaalsContact O-CB 3.31Å; A368-H371 WeakPolarHBondContact O-CB 3.48Å; A368-H371 PolarHBondContact O-N 3.15Å; A368-I372 PolarHBondContact O-N 3.28Å; A368-I372 VanDerWaalsContact O-N 3.12Å; A368-I397 HydrophobicContact CB-CB 4.48Å; A368-I397 HydrophobicContact CB-CD1 4.23Å; A368-S400 WeakPolarHBondContact CB-OG 3.33Å; A368-M401 HydrophobicContact CB-CE 3.21Å
369	F	92.4	Very high	88.6	Confident	12 Å²	12	64.3 Å²	64.3	5%	0.053	32%	0.316	C	S	.	.	H	α-helix	trans	-73.7	-32.9	176.2	-88.9	-108.3	0	0	0	112.3	V365 E366 H371 I372 Q373 M401 L427 C430 M435 P437 F440	V365-F369 HydrophobicContact CG1-CD2 3.68Å; V365-F369 HydrophobicContact CG1-CE2 3.68Å; V365-F369 WeakPolarHBondContact O-CD2 3.45Å; V365-F369 PolarHBondContact O-N 2.7Å; E366-F369 PolarHBondContact O-N 3.27Å; F369-H371 PolarHBondContact O-N 3.15Å; F369-I372 HydrophobicContact CD1-CD1 4.42Å; F369-I372 HydrophobicContact CG-CD1 4.35Å; F369-I372 PolarHBondContact O-N 2.98Å; F369-Q373 WeakPolarHBondContact O-CG 3.39Å; F369-Q373 PolarHBondContact O-N 3.11Å; F369-M401 HydrophobicContact CD2-CE 4.49Å; F369-M401 HydrophobicContact CE2-CE 4.44Å; F369-L427 HydrophobicContact CE2-CD1 3.74Å; F369-L427 HydrophobicContact CZ-CD1 3.83Å; F369-C430 HydrophobicContact CE1-CB 4.47Å; F369-C430 HydrophobicContact CZ-CB 4.17Å; F369-M435 WeakPolarHBondContact CE1-O 3.33Å; F369-P437 HydrophobicContact CB-CG 3.61Å; F369-P437 HydrophobicContact CD1-CG 4.09Å; F369-P437 HydrophobicContact CD2-CB 4.34Å; F369-P437 HydrophobicContact CD2-CG 4.25Å; F369-P437 HydrophobicContact CG-CB 4.31Å; F369-P437 HydrophobicContact CG-CG 3.73Å; F369-F440 HydrophobicContact CE2-CB 4.13Å; F369-F440 HydrophobicContact CE2-CD1 4.35Å; F369-F440 HydrophobicContact CE2-CG 4.24Å; F369-F440 HydrophobicContact CZ-CB 3.83Å; F369-F440 HydrophobicContact CZ-CG 4.26Å
370	I	91.2	Very high	87.2	Confident	76 Å²	76	69.2 Å²	69.2	39%	0.39	33%	0.329	S	S	.	.	H	α-helix	trans	-60.6	-38.4	168.8	-69.3	165	0	0	0	110	E366 E367 Q373 R374	E366-I370 VanDerWaalsContact O-CG1 3.27Å; E366-I370 WeakPolarHBondContact O-CG1 3.06Å; E366-I370 PolarHBondContact O-N 3.15Å; E367-I370 PolarHBondContact O-N 3.3Å; I370-Q373 PolarHBondContact O-N 3.03Å; I370-R374 WeakPolarHBondContact O-CG 3.41Å; I370-R374 PolarHBondContact O-N 3.39Å
371	H	88.7	Confident	85.8	Confident	97 Å²	97	70.8 Å²	70.8	45%	0.449	34%	0.342	S	S	.	.	H	α-helix	trans	-62.8	-41.7	174.5	-169.9	-92.9	0	0	0	112.2	E367 A368 F369 R374 L375	E367-H371 PolarHBondContact O-N 3.1Å; A368-H371 VanDerWaalsContact O-CB 3.31Å; A368-H371 WeakPolarHBondContact O-CB 3.48Å; A368-H371 PolarHBondContact O-N 3.15Å; F369-H371 PolarHBondContact O-N 3.15Å; H371-R374 PolarHBondContact O-N 2.82Å; H371-L375 WeakPolarHBondContact ND1-CD1 3.48Å; H371-L375 WeakPolarHBondContact O-CG 3.26Å; H371-L375 PolarHBondContact O-N 3.3Å
372	I	85.3	Confident	84.3	Confident	10 Å²	10	78.3 Å²	78.3	5%	0.051	37%	0.374	C	S	.	.	H	α-helix	trans	-60.9	-47.3	173.8	-61.9	165.3	0	0	0	111.1	A368 F369 R374 L375 Q376 I397 I431	A368-I372 PolarHBondContact O-N 3.28Å; A368-I372 VanDerWaalsContact O-N 3.12Å; F369-I372 HydrophobicContact CD1-CD1 4.42Å; F369-I372 HydrophobicContact CG-CD1 4.35Å; F369-I372 PolarHBondContact O-N 2.98Å; I372-R374 VanDerWaalsContact C-N 3.25Å; I372-R374 PolarHBondContact O-N 3.19Å; I372-L375 PolarHBondContact O-N 2.95Å; I372-L375 VanDerWaalsContact O-N 3.16Å; I372-Q376 HydrophobicContact CG2-CG 4.13Å; I372-Q376 WeakPolarHBondContact O-CG 3.22Å; I372-Q376 PolarHBondContact O-N 3.1Å; I372-I397 HydrophobicContact CD1-CD1 3.26Å; I372-I397 HydrophobicContact CD1-CG1 3.9Å; I372-I397 HydrophobicContact CG1-CB 4.44Å; I372-I397 HydrophobicContact CG1-CD1 3.88Å; I372-I397 HydrophobicContact CG1-CG1 4.07Å; I372-I397 HydrophobicContact CG1-CG2 3.79Å; I372-I431 HydrophobicContact CD1-CD1 3.67Å; I372-I431 HydrophobicContact CD1-CG1 3.72Å; I372-I431 HydrophobicContact CG2-CG2 4.44Å
373	Q	83.9	Confident	82.4	Confident	119 Å²	119	80.7 Å²	80.7	56%	0.556	40%	0.398	S	S	*	.	H	α-helix	trans	-59.7	-39.1	-179.9	-74.2	178.4	-14.8	0	0	111.6	F369 I370 Q376 V377	F369-Q373 WeakPolarHBondContact O-CG 3.39Å; F369-Q373 PolarHBondContact O-N 3.11Å; I370-Q373 PolarHBondContact O-N 3.03Å; Q373-Q376 PolarHBondContact O-N 3.37Å; Q373-V377 VanDerWaalsContact O-CG2 3.27Å; Q373-V377 WeakPolarHBondContact O-CG2 3.21Å; Q373-V377 PolarHBondContact O-N 2.92Å
374	R	84.1	Confident	80.5	Confident	159 Å²	159	84.1 Å²	84.1	60%	0.6	42%	0.421	S	S	*	.	H	α-helix	trans	-65.1	-46.3	174.5	-70.6	175	-174.4	175.2	2.7	111.9	I370 H371 I372 Q376 V377 E378	I370-R374 WeakPolarHBondContact O-CG 3.41Å; I370-R374 PolarHBondContact O-N 3.39Å; H371-R374 PolarHBondContact O-N 2.82Å; I372-R374 VanDerWaalsContact C-N 3.25Å; I372-R374 PolarHBondContact O-N 3.19Å; R374-Q376 VanDerWaalsContact C-N 3.31Å; R374-Q376 PolarHBondContact O-N 2.87Å; R374-V377 PolarHBondContact O-N 3.34Å; R374-E378 WeakPolarHBondContact O-CG 3.2Å; R374-E378 PolarHBondContact O-N 2.96Å
375	L	79.8	Confident	78.6	Confident	42 Å²	42	87 Å²	87	22%	0.22	45%	0.452	C	S	.	.	H	α-helix	trans	-60.1	-41	176.2	-71.8	174.7	0	0	0	112	H371 I372 V377 E378 E379	H371-L375 WeakPolarHBondContact ND1-CD1 3.48Å; H371-L375 WeakPolarHBondContact O-CG 3.26Å; H371-L375 PolarHBondContact O-N 3.3Å; I372-L375 PolarHBondContact O-N 2.95Å; I372-L375 VanDerWaalsContact O-N 3.16Å; L375-V377 PolarHBondContact O-N 3.4Å; L375-E378 PolarHBondContact O-N 2.91Å; L375-E379 WeakPolarHBondContact O-CB 3.09Å; L375-E379 WeakPolarHBondContact O-CG 3.47Å; L375-E379 PolarHBondContact O-N 2.88Å
376	Q	76.4	Confident	76.8	Confident	83 Å²	83	95.5 Å²	95.5	39%	0.388	49%	0.492	S	S	.	.	H	α-helix	trans	-64.1	-38.9	176.2	-73.9	177.3	-17.8	0	0	112.3	I372 Q373 R374 Q380	I372-Q376 HydrophobicContact CG2-CG 4.13Å; I372-Q376 WeakPolarHBondContact O-CG 3.22Å; I372-Q376 PolarHBondContact O-N 3.1Å; Q373-Q376 PolarHBondContact O-N 3.37Å; R374-Q376 VanDerWaalsContact C-N 3.31Å; R374-Q376 PolarHBondContact O-N 2.87Å; Q376-Q380 WeakPolarHBondContact O-CB 3.08Å; Q376-Q380 VanDerWaalsContact O-CG 3.27Å; Q376-Q380 WeakPolarHBondContact O-CG 3.16Å; Q376-Q380 PolarHBondContact O-N 2.95Å
377	V	79.4	Confident	75.3	Confident	77 Å²	77	98.8 Å²	98.8	47%	0.467	52%	0.517	S	S	.	.	H	α-helix	trans	-68.9	-38.7	175.4	171.4	0	0	0	0	111.4	Q373 R374 L375 Q381	Q373-V377 VanDerWaalsContact O-CG2 3.27Å; Q373-V377 WeakPolarHBondContact O-CG2 3.21Å; Q373-V377 PolarHBondContact O-N 2.92Å; R374-V377 PolarHBondContact O-N 3.34Å; L375-V377 PolarHBondContact O-N 3.4Å; V377-Q381 WeakPolarHBondContact O-CG 3.1Å; V377-Q381 PolarHBondContact O-N 3.4Å
378	E	76.1	Confident	73.9	Confident	112 Å²	112	95 Å²	95	52%	0.523	50%	0.499	S	S	.	.	H	α-helix	trans	-68.5	-35	175.6	-72.6	174.2	-167	0	0	112.4	R374 L375 Q381	R374-E378 WeakPolarHBondContact O-CG 3.2Å; R374-E378 PolarHBondContact O-N 2.96Å; L375-E378 PolarHBondContact O-N 2.91Å; E378-Q381 PolarHBondContact O-N 2.99Å
379	E	69.3	Low	73.4	Confident	58 Å²	58	99.1 Å²	99.1	27%	0.271	52%	0.521	S	S	.	.	H	α-helix	trans	-73.5	-35.7	174.9	-78.3	-173.4	165.5	0	0	113.1	L375 Q381 K382 M388	L375-E379 WeakPolarHBondContact O-CB 3.09Å; L375-E379 WeakPolarHBondContact O-CG 3.47Å; L375-E379 PolarHBondContact O-N 2.88Å; E379-Q381 PolarHBondContact O-N 3.15Å; E379-K382 PolarHBondContact O-N 3.45Å; E379-M388 WeakPolarHBondContact OE1-CB 3.3Å; E379-M388 WeakPolarHBondContact OE1-CE 3.25Å; E379-M388 WeakPolarHBondContact OE2-CB 3.34Å
380	Q	65.5	Low	73	Confident	162 Å²	162	100.4 Å²	100.4	76%	0.757	53%	0.53	S	S	*	.	H	α-helix	trans	-62.6	-20.9	172.3	-78.5	174.9	8.6	0	0	113.1	Q376	Q376-Q380 WeakPolarHBondContact O-CB 3.08Å; Q376-Q380 VanDerWaalsContact O-CG 3.27Å; Q376-Q380 WeakPolarHBondContact O-CG 3.16Å; Q376-Q380 PolarHBondContact O-N 2.95Å
381	Q	67	Low	72.8	Confident	160 Å²	160	104 Å²	104	75%	0.748	54%	0.539	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.8	-10.5	174.6	-68.1	174.6	16.6	0	0	113.2	V377 E378 E379	V377-Q381 WeakPolarHBondContact O-CG 3.1Å; V377-Q381 PolarHBondContact O-N 3.4Å; E378-Q381 PolarHBondContact O-N 2.99Å; E379-Q381 PolarHBondContact O-N 3.15Å
382	K	63.1	Low	72.8	Confident	158 Å²	158	104.8 Å²	104.8	69%	0.687	54%	0.543	S	S	*	.	S	Bend	trans	-93.5	155.8	177.1	-71.6	178.5	-179	174	0	111.5	E379	E379-K382 PolarHBondContact O-N 3.45Å
383	A	58.2	Low	72.9	Confident	85 Å²	85	104.8 Å²	104.8	70%	0.702	55%	0.545	S	S	*	.			trans	-57.4	148.3	-178.2	0	0	0	0	0	112.5	G385	A383-G385 VanDerWaalsContact C-N 3.29Å; A383-G385 PolarHBondContact O-N 2.89Å
384	P	55.3	Low	73.1	Confident	142 Å²	142	99.1 Å²	99.1	92%	0.922	52%	0.518	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.5	67.2	-166.1	32.5	-37	0	0	0	113.3
385	G	56.1	Low	73.5	Confident	74 Å²	74	97.3 Å²	97.3	76%	0.763	52%	0.516	S	S	*	.	T	Hydrogen-bonded Turn	trans	-138	-13.3	-178.5	0	0	0	0	0	116.2	A383	A383-G385 VanDerWaalsContact C-N 3.29Å; A383-G385 PolarHBondContact O-N 2.89Å
386	E	57.9	Low	73.9	Confident	179 Å²	179	98.3 Å²	98.3	84%	0.836	53%	0.531	S	S	*	.			trans	-143	76.2	-173.7	-147.4	170.4	-156.8	0	0	109.8
387	V	63.4	Low	74.5	Confident	140 Å²	140	94.5 Å²	94.5	85%	0.848	51%	0.513	S	S	*	.	P	Polyproline II helix	trans	-77.3	118.4	170.1	-178.5	0	0	0	0	106.9	D389	V387-D389 PolarHBondContact O-N 3.42Å
388	M	67.1	Low	75.1	Confident	47 Å²	47	91.6 Å²	91.6	23%	0.232	49%	0.494	C	S	.	.	P	Polyproline II helix	trans	-58.6	133.9	179.4	-174.6	-177	-59.2	0	0	111.1	E379 P390 E392 A393	E379-M388 WeakPolarHBondContact OE1-CB 3.3Å; E379-M388 WeakPolarHBondContact OE1-CE 3.25Å; E379-M388 WeakPolarHBondContact OE2-CB 3.34Å; M388-P390 WeakPolarHBondContact O-CD 3.42Å; M388-E392 HydrophobicContact CG-CB 4.07Å; M388-E392 HydrophobicContact CG-CG 4.2Å; M388-A393 HydrophobicContact CG-CB 4.27Å; M388-A393 WeakPolarHBondContact SD-CA 3.49Å; M388-A393 HydrophobicContact SD-CB 3.57Å; M388-A393 VanDerWaalsContact SD-CB 3.57Å
389	D	81.9	Confident	75.9	Confident	89 Å²	89	90.7 Å²	90.7	48%	0.476	50%	0.498	S	S	.	.	P	Polyproline II helix	trans	-62.9	128.9	173.8	-179.7	16.8	0	0	0	109	V387 R391 E392 A393	V387-D389 PolarHBondContact O-N 3.42Å; D389-R391 PolarHBondContact O-N 2.73Å; D389-E392 HydrophobicContact CB-CB 4.23Å; D389-E392 WeakPolarHBondContact O-CA 3.4Å; D389-E392 WeakPolarHBondContact O-CB 3.31Å; D389-E392 PolarHBondContact O-N 3.41Å; D389-A393 PolarHBondContact O-N 3.34Å
390	P	83.7	Confident	77	Confident	39 Å²	39	91.5 Å²	91.5	25%	0.253	51%	0.51	S	S	.	.	H	α-helix	trans	-52	-26.7	177.3	-31.4	36	0	0	0	114.8	M388 A394 I431 T432	M388-P390 WeakPolarHBondContact O-CD 3.42Å; P390-A394 WeakPolarHBondContact O-CB 3.41Å; P390-A394 PolarHBondContact O-N 3.13Å; P390-A394 VanDerWaalsContact O-N 3.07Å; P390-I431 HydrophobicContact CB-CG2 4.32Å; P390-T432 VanDerWaalsContact CB-OG1 3.28Å; P390-T432 WeakPolarHBondContact CB-OG1 3.48Å
391	R	87.2	Confident	78.3	Confident	152 Å²	152	83.8 Å²	83.8	57%	0.574	47%	0.474	S	S	*	.	H	α-helix	trans	-71.4	-38.6	172.5	-71.1	-175	169.5	-160	-2.2	112.9	D389 A394 Q395 A428	D389-R391 PolarHBondContact O-N 2.73Å; R391-A394 PolarHBondContact O-N 2.97Å; R391-Q395 WeakPolarHBondContact O-CG 3.46Å; R391-Q395 PolarHBondContact O-N 3.37Å; R391-A428 HydrophobicContact CG-CB 3.92Å
392	E	88.3	Confident	79.5	Confident	114 Å²	114	76.8 Å²	76.8	53%	0.533	44%	0.444	S	S	.	.	H	α-helix	trans	-66.4	-44.5	175.5	-174.5	176.1	-170.5	0	0	110.6	M388 D389 A394 Q395 A396	M388-E392 HydrophobicContact CG-CB 4.07Å; M388-E392 HydrophobicContact CG-CG 4.2Å; D389-E392 HydrophobicContact CB-CB 4.23Å; D389-E392 WeakPolarHBondContact O-CA 3.4Å; D389-E392 WeakPolarHBondContact O-CB 3.31Å; D389-E392 PolarHBondContact O-N 3.41Å; E392-A394 VanDerWaalsContact C-N 3.31Å; E392-A394 PolarHBondContact O-N 2.87Å; E392-Q395 PolarHBondContact O-N 3.48Å; E392-Q395 VanDerWaalsContact O-N 3.12Å; E392-A396 PolarHBondContact O-N 2.93Å
393	A	86.7	Confident	80.9	Confident	10 Å²	10	77.7 Å²	77.7	8%	0.083	44%	0.443	C	S	.	.	H	α-helix	trans	-56.1	-45.9	172.9	0	0	0	0	0	111.7	M388 D389 Q395 A396 I397 I431	M388-A393 HydrophobicContact CG-CB 4.27Å; M388-A393 WeakPolarHBondContact SD-CA 3.49Å; M388-A393 HydrophobicContact SD-CB 3.57Å; M388-A393 VanDerWaalsContact SD-CB 3.57Å; D389-A393 PolarHBondContact O-N 3.34Å; A393-Q395 PolarHBondContact O-N 2.8Å; A393-A396 PolarHBondContact O-N 3.12Å; A393-I397 WeakPolarHBondContact O-CG1 3.44Å; A393-I397 PolarHBondContact O-N 2.91Å; A393-I431 HydrophobicContact CB-CD1 4.08Å
394	A	89.6	Confident	82.5	Confident	0 Å²	0	74.7 Å²	74.7	0%	0	42%	0.418	C	S	.	.	H	α-helix	trans	-61.2	-42.1	176.2	0	0	0	0	0	112.5	P390 R391 E392 F398 L427 A428 I431	P390-A394 WeakPolarHBondContact O-CB 3.41Å; P390-A394 PolarHBondContact O-N 3.13Å; P390-A394 VanDerWaalsContact O-N 3.07Å; R391-A394 PolarHBondContact O-N 2.97Å; E392-A394 VanDerWaalsContact C-N 3.31Å; E392-A394 PolarHBondContact O-N 2.87Å; A394-F398 WeakPolarHBondContact O-CB 3.41Å; A394-F398 PolarHBondContact O-N 3.39Å; A394-L427 HydrophobicContact CB-CB 4.08Å; A394-L427 HydrophobicContact CB-CD2 3.89Å; A394-L427 HydrophobicContact CB-CG 3.82Å; A394-L427 WeakPolarHBondContact O-CD2 3.48Å; A394-A428 HydrophobicContact CB-CB 4.08Å; A394-I431 HydrophobicContact CB-CD1 3.95Å
395	Q	90.6	Very high	84.3	Confident	120 Å²	120	68 Å²	68	56%	0.561	37%	0.374	S	S	*	.	H	α-helix	trans	-66.5	-37.7	177.5	-73.6	176.2	10.5	0	0	112.5	R391 E392 A393 P399 L424	R391-Q395 WeakPolarHBondContact O-CG 3.46Å; R391-Q395 PolarHBondContact O-N 3.37Å; E392-Q395 PolarHBondContact O-N 3.48Å; E392-Q395 VanDerWaalsContact O-N 3.12Å; A393-Q395 PolarHBondContact O-N 2.8Å; Q395-P399 VanDerWaalsContact O-CD 3.23Å; Q395-P399 WeakPolarHBondContact O-CD 3.48Å; Q395-L424 HydrophobicContact CG-CD1 4.33Å; Q395-L424 HydrophobicContact CG-CD2 4.33Å
396	A	88.7	Confident	86.1	Confident	63 Å²	63	68.9 Å²	68.9	52%	0.521	36%	0.359	S	S	.	.	H	α-helix	trans	-65.3	-40.7	179.3	0	0	0	0	0	112.4	E392 A393	E392-A396 PolarHBondContact O-N 2.93Å; A393-A396 PolarHBondContact O-N 3.12Å
397	I	89.5	Confident	87.7	Confident	4 Å²	4	63.3 Å²	63.3	2%	0.021	33%	0.332	C	S	.	.	H	α-helix	trans	-90.9	-23.5	-176.1	60.4	130.7	0	0	0	114.4	A368 I372 A393 P399 S400 M401 L427	A368-I397 HydrophobicContact CB-CB 4.48Å; A368-I397 HydrophobicContact CB-CD1 4.23Å; I372-I397 HydrophobicContact CD1-CD1 3.26Å; I372-I397 HydrophobicContact CD1-CG1 3.9Å; I372-I397 HydrophobicContact CG1-CB 4.44Å; I372-I397 HydrophobicContact CG1-CD1 3.88Å; I372-I397 HydrophobicContact CG1-CG1 4.07Å; I372-I397 HydrophobicContact CG1-CG2 3.79Å; A393-I397 WeakPolarHBondContact O-CG1 3.44Å; A393-I397 PolarHBondContact O-N 2.91Å; I397-P399 VanDerWaalsContact C-CD 3.42Å; I397-S400 WeakPolarHBondContact O-CB 3.44Å; I397-S400 PolarHBondContact O-N 3.37Å; I397-S400 VanDerWaalsContact O-N 3.1Å; I397-S400 PolarHBondContact O-OG 3.1Å; I397-M401 HydrophobicContact CD1-CE 3.67Å; I397-L427 HydrophobicContact CD1-CD1 3.96Å; I397-L427 HydrophobicContact CD1-CD2 3.73Å; I397-L427 HydrophobicContact CD1-CG 4.17Å; I397-L427 HydrophobicContact CG1-CD2 4.11Å
398	F	92.5	Very high	89.2	Confident	15 Å²	15	57.3 Å²	57.3	7%	0.066	29%	0.294	C	S	.	.	H	α-helix	trans	-52.2	-41.6	-177.8	178.5	-112.7	0	0	0	114.6	A394 S400 M401 A402 L405 M420 I423 L424 L427	A394-F398 WeakPolarHBondContact O-CB 3.41Å; A394-F398 PolarHBondContact O-N 3.39Å; F398-S400 PolarHBondContact O-N 2.91Å; F398-S400 VanDerWaalsContact O-N 3.16Å; F398-M401 HydrophobicContact CD2-CG 4.38Å; F398-M401 WeakPolarHBondContact O-CG 3.23Å; F398-M401 PolarHBondContact O-N 2.9Å; F398-M401 VanDerWaalsContact O-N 3.15Å; F398-A402 HydrophobicContact CD1-CB 4.18Å; F398-A402 HydrophobicContact CD2-CB 4.45Å; F398-A402 HydrophobicContact CE1-CB 3.86Å; F398-A402 HydrophobicContact CE2-CB 4.13Å; F398-A402 HydrophobicContact CG-CB 4.47Å; F398-A402 HydrophobicContact CZ-CB 3.83Å; F398-A402 VanDerWaalsContact O-CB 3.25Å; F398-A402 WeakPolarHBondContact O-CB 3.21Å; F398-A402 PolarHBondContact O-N 3.27Å; F398-L405 HydrophobicContact CE2-CD2 4.43Å; F398-M420 HydrophobicContact CD1-CE 4.35Å; F398-M420 HydrophobicContact CE1-CE 4.1Å; F398-M420 HydrophobicContact CE1-CG 3.89Å; F398-M420 HydrophobicContact CE1-SD 4.09Å; F398-M420 HydrophobicContact CZ-CG 4.23Å; F398-I423 HydrophobicContact CD2-CG2 4.16Å; F398-I423 HydrophobicContact CE2-CB 4.38Å; F398-I423 HydrophobicContact CE2-CG2 3.58Å; F398-I423 HydrophobicContact CZ-CG2 4.44Å; F398-L424 HydrophobicContact CB-CD2 3.6Å; F398-L424 HydrophobicContact CD1-CD2 4Å; F398-L424 HydrophobicContact CD2-CD2 4.19Å; F398-L424 HydrophobicContact CG-CD2 3.67Å; F398-L427 HydrophobicContact CB-CD2 4.28Å
399	P	93.3	Very high	90.3	Very high	93 Å²	93	55.3 Å²	55.3	60%	0.604	28%	0.284	S	S	*	.	H	α-helix	trans	-55.9	-32.7	178.5	-27.7	35.9	0	0	0	114.6	Q395 I397 M401	Q395-P399 VanDerWaalsContact O-CD 3.23Å; Q395-P399 WeakPolarHBondContact O-CD 3.48Å; I397-P399 VanDerWaalsContact C-CD 3.42Å; P399-M401 VanDerWaalsContact C-N 3.34Å; P399-M401 PolarHBondContact O-N 3.04Å
400	S	90.6	Very high	90.7	Very high	76 Å²	76	59 Å²	59	53%	0.531	29%	0.291	S	S	.	.	H	α-helix	trans	-66.2	-34.5	-179.6	70.5	0	0	0	0	112.8	A368 I397 F398	A368-S400 WeakPolarHBondContact CB-OG 3.33Å; I397-S400 WeakPolarHBondContact O-CB 3.44Å; I397-S400 PolarHBondContact O-N 3.37Å; I397-S400 VanDerWaalsContact O-N 3.1Å; I397-S400 PolarHBondContact O-OG 3.1Å; F398-S400 PolarHBondContact O-N 2.91Å; F398-S400 VanDerWaalsContact O-N 3.16Å
401	M	93.2	Very high	90.9	Very high	0 Å²	0	58.7 Å²	58.7	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-102.7	-20.4	-179	64.7	175.7	70.3	0	0	113.9	V365 A368 F369 I397 F398 P399 R403 A404 L405 L427 F440	V365-M401 HydrophobicContact CG1-CE 4.31Å; V365-M401 HydrophobicContact CG2-CB 4.05Å; V365-M401 HydrophobicContact CG2-CE 4.22Å; V365-M401 HydrophobicContact CG2-SD 3.97Å; A368-M401 HydrophobicContact CB-CE 3.21Å; F369-M401 HydrophobicContact CD2-CE 4.49Å; F369-M401 HydrophobicContact CE2-CE 4.44Å; I397-M401 HydrophobicContact CD1-CE 3.67Å; F398-M401 HydrophobicContact CD2-CG 4.38Å; F398-M401 WeakPolarHBondContact O-CG 3.23Å; F398-M401 PolarHBondContact O-N 2.9Å; F398-M401 VanDerWaalsContact O-N 3.15Å; P399-M401 VanDerWaalsContact C-N 3.34Å; P399-M401 PolarHBondContact O-N 3.04Å; M401-R403 VanDerWaalsContact C-N 3.31Å; M401-R403 PolarHBondContact O-N 3.44Å; M401-A404 WeakPolarHBondContact O-CB 3.48Å; M401-A404 PolarHBondContact O-N 2.99Å; M401-L405 PolarHBondContact O-N 2.91Å; M401-L427 HydrophobicContact CE-CD1 4.47Å; M401-L427 HydrophobicContact SD-CD2 4.4Å; M401-F440 HydrophobicContact SD-CE1 3.85Å; M401-F440 HydrophobicContact SD-CZ 4.1Å
402	A	91.6	Very high	90.9	Very high	13 Å²	13	52.4 Å²	52.4	11%	0.107	27%	0.267	C	S	.	.	H	α-helix	trans	-53.8	-43.9	-169.9	0	0	0	0	0	113.1	F398 A404 L405 Q406	F398-A402 HydrophobicContact CD1-CB 4.18Å; F398-A402 HydrophobicContact CD2-CB 4.45Å; F398-A402 HydrophobicContact CE1-CB 3.86Å; F398-A402 HydrophobicContact CE2-CB 4.13Å; F398-A402 HydrophobicContact CG-CB 4.47Å; F398-A402 HydrophobicContact CZ-CB 3.83Å; F398-A402 VanDerWaalsContact O-CB 3.25Å; F398-A402 WeakPolarHBondContact O-CB 3.21Å; F398-A402 PolarHBondContact O-N 3.27Å; A402-A404 PolarHBondContact O-N 2.67Å; A402-L405 PolarHBondContact O-N 3.25Å; A402-Q406 WeakPolarHBondContact O-CB 3.49Å; A402-Q406 VanDerWaalsContact O-CG 3.26Å; A402-Q406 WeakPolarHBondContact O-CG 3.42Å; A402-Q406 PolarHBondContact O-N 3.14Å
403	R	93.1	Very high	90.8	Very high	177 Å²	177	50.4 Å²	50.4	67%	0.668	26%	0.255	S	S	*	.	H	α-helix	trans	-66.7	-37.7	-179.9	-174.3	177.5	-175.8	-126.1	11.2	112.4	M401 K407	M401-R403 VanDerWaalsContact C-N 3.31Å; M401-R403 PolarHBondContact O-N 3.44Å; R403-K407 HydrophobicContact CG-CD 4.44Å; R403-K407 VanDerWaalsContact NH2-NZ 3.1Å; R403-K407 WeakPolarHBondContact O-CB 3.38Å; R403-K407 VanDerWaalsContact O-CG 3.27Å; R403-K407 WeakPolarHBondContact O-CG 3.23Å; R403-K407 PolarHBondContact O-N 3.19Å
404	A	93.2	Very high	90.7	Very high	21 Å²	21	51.1 Å²	51.1	17%	0.174	26%	0.256	C	S	.	.	H	α-helix	trans	-68.1	-44.2	177.7	0	0	0	0	0	110.1	L361 A364 M401 A402 K407 Y408	L361-A404 HydrophobicContact CB-CB 4.45Å; L361-A404 HydrophobicContact CD1-CB 4.23Å; A364-A404 HydrophobicContact CB-CB 3.96Å; M401-A404 WeakPolarHBondContact O-CB 3.48Å; M401-A404 PolarHBondContact O-N 2.99Å; A402-A404 PolarHBondContact O-N 2.67Å; A404-K407 PolarHBondContact O-N 3.32Å; A404-Y408 PolarHBondContact O-N 2.95Å
405	L	92.8	Very high	90.5	Very high	1 Å²	1	55.4 Å²	55.4	1%	0.005	28%	0.277	C	S	.	.	H	α-helix	trans	-63.6	-51.4	178.8	-176.6	60.8	0	0	0	111.7	L361 F398 M401 A402 K407 Y408 L409 I423 Y444	L361-L405 HydrophobicContact CD1-CB 3.8Å; L361-L405 HydrophobicContact CD1-CD1 4.02Å; L361-L405 HydrophobicContact CD2-CD1 3.83Å; F398-L405 HydrophobicContact CE2-CD2 4.43Å; M401-L405 PolarHBondContact O-N 2.91Å; A402-L405 PolarHBondContact O-N 3.25Å; L405-K407 VanDerWaalsContact C-N 3.3Å; L405-K407 PolarHBondContact O-N 3.47Å; L405-Y408 WeakPolarHBondContact O-CB 3.5Å; L405-Y408 PolarHBondContact O-N 2.79Å; L405-Y408 VanDerWaalsContact O-N 3.09Å; L405-L409 HydrophobicContact CD1-CD1 4.17Å; L405-L409 HydrophobicContact CD1-CG 4.16Å; L405-L409 HydrophobicContact CG-CD1 4.01Å; L405-L409 HydrophobicContact CG-CG 4.38Å; L405-L409 WeakPolarHBondContact O-CG 3.3Å; L405-L409 PolarHBondContact O-N 2.92Å; L405-I423 HydrophobicContact CD2-CD1 3.95Å; L405-I423 HydrophobicContact CD2-CG1 4.39Å; L405-I423 HydrophobicContact CD2-CG2 3.78Å; L405-Y444 HydrophobicContact CD1-CD1 4.26Å; L405-Y444 HydrophobicContact CD1-CD2 4.19Å; L405-Y444 HydrophobicContact CD1-CG 3.97Å
406	Q	92.6	Very high	90.1	Very high	94 Å²	94	52.4 Å²	52.4	44%	0.439	26%	0.262	S	S	.	.	H	α-helix	trans	-58.8	-40.1	177.6	-73.9	177.9	-1.5	0	0	112.6	A402 Y408 R410	A402-Q406 WeakPolarHBondContact O-CB 3.49Å; A402-Q406 VanDerWaalsContact O-CG 3.26Å; A402-Q406 WeakPolarHBondContact O-CG 3.42Å; A402-Q406 PolarHBondContact O-N 3.14Å; Q406-Y408 VanDerWaalsContact C-N 3.35Å; Q406-R410 WeakPolarHBondContact O-CB 3.44Å; Q406-R410 VanDerWaalsContact O-CG 3.27Å; Q406-R410 WeakPolarHBondContact O-CG 3.47Å; Q406-R410 PolarHBondContact O-N 3.29Å
407	K	92.6	Very high	89.6	Confident	62 Å²	62	50.4 Å²	50.4	27%	0.27	24%	0.242	S	C	.	.	H	α-helix	trans	-67.3	-37.2	176.9	-77.2	-177	-178.8	-174.9	0	112	R403 A404 L405 T411	R403-K407 HydrophobicContact CG-CD 4.44Å; R403-K407 VanDerWaalsContact NH2-NZ 3.1Å; R403-K407 WeakPolarHBondContact O-CB 3.38Å; R403-K407 VanDerWaalsContact O-CG 3.27Å; R403-K407 WeakPolarHBondContact O-CG 3.23Å; R403-K407 PolarHBondContact O-N 3.19Å; A404-K407 PolarHBondContact O-N 3.32Å; L405-K407 VanDerWaalsContact C-N 3.3Å; L405-K407 PolarHBondContact O-N 3.47Å; K407-T411 WeakPolarHBondContact O-CB 3.45Å; K407-T411 PolarHBondContact O-N 3.07Å; K407-T411 PolarHBondContact O-OG1 3.09Å
408	Y	93.5	Very high	89.4	Confident	13 Å²	13	50.9 Å²	50.9	5%	0.051	24%	0.243	C	C	.	.	H	α-helix	trans	-64.1	-56	173.9	179.1	-99.1	0	0	0	110.3	V354 R357 K358 L361 A404 L405 Q406 R410 T411 T412 Y444 L445	V354-Y408 HydrophobicContact CG1-CE2 4.14Å; R357-Y408 HydrophobicContact CB-CD2 4.01Å; K358-Y408 HydrophobicContact CB-CD2 4.28Å; K358-Y408 HydrophobicContact CB-CE2 3.88Å; K358-Y408 HydrophobicContact CG-CE2 4.5Å; L361-Y408 HydrophobicContact CD2-CD1 3.87Å; L361-Y408 HydrophobicContact CD2-CG 3.86Å; A404-Y408 PolarHBondContact O-N 2.95Å; L405-Y408 WeakPolarHBondContact O-CB 3.5Å; L405-Y408 PolarHBondContact O-N 2.79Å; L405-Y408 VanDerWaalsContact O-N 3.09Å; Q406-Y408 VanDerWaalsContact C-N 3.35Å; Y408-R410 VanDerWaalsContact C-N 3.32Å; Y408-R410 PolarHBondContact O-N 2.8Å; Y408-T411 WeakPolarHBondContact O-CA 3.46Å; Y408-T411 WeakPolarHBondContact O-CB 3.39Å; Y408-T411 PolarHBondContact O-N 3.23Å; Y408-T412 HydrophobicContact CD1-CG2 4.46Å; Y408-T412 HydrophobicContact CD2-CG2 4.37Å; Y408-T412 HydrophobicContact CE1-CG2 3.98Å; Y408-T412 HydrophobicContact CE2-CG2 3.89Å; Y408-T412 PolarHBondContact O-N 3.31Å; Y408-T412 PolarHBondContact O-OG1 3.47Å; Y408-Y444 WeakPolarHBondContact CE1-O 3.35Å; Y408-L445 HydrophobicContact CD1-CD2 4.4Å; Y408-L445 HydrophobicContact CE1-CD2 3.71Å; Y408-L445 HydrophobicContact CE2-CD2 4.03Å; Y408-L445 VanDerWaalsContact CZ-CD2 3.48Å; Y408-L445 WeakPolarHBondContact OH-CD2 3.26Å
409	L	90.6	Very high	89.2	Confident	6 Å²	6	53 Å²	53	3%	0.031	26%	0.26	C	S	.	.	H	α-helix	trans	-57.3	-39.3	-178.9	-66.3	178.7	0	0	0	113.2	L405 T412 R413 Q414 Q415 H418 I423 Y444	L405-L409 HydrophobicContact CD1-CD1 4.17Å; L405-L409 HydrophobicContact CD1-CG 4.16Å; L405-L409 HydrophobicContact CG-CD1 4.01Å; L405-L409 HydrophobicContact CG-CG 4.38Å; L405-L409 WeakPolarHBondContact O-CG 3.3Å; L405-L409 PolarHBondContact O-N 2.92Å; L409-T412 WeakPolarHBondContact CA-OG1 3.44Å; L409-T412 PolarHBondContact O-OG1 3.49Å; L409-R413 CarbonylContact O-C 3.55Å; L409-R413 WeakPolarHBondContact O-CA 3.45Å; L409-R413 PolarHBondContact O-N 2.77Å; L409-Q414 HydrophobicContact CD2-CB 3.9Å; L409-Q414 PolarHBondContact O-N 2.95Å; L409-Q415 PolarHBondContact O-OE1 3.24Å; L409-H418 HydrophobicContact CD1-CB 4.12Å; L409-I423 HydrophobicContact CD1-CD1 4.48Å; L409-Y444 HydrophobicContact CD2-CD1 4.28Å
410	R	89.8	Confident	88.9	Confident	166 Å²	166	54.2 Å²	54.2	63%	0.626	26%	0.259	S	S	*	.	H	α-helix	trans	-68.3	-35.2	174.4	-73.4	178.4	-171.9	171.7	5.1	112.8	Q406 Y408 R413 Q415	Q406-R410 WeakPolarHBondContact O-CB 3.44Å; Q406-R410 VanDerWaalsContact O-CG 3.27Å; Q406-R410 WeakPolarHBondContact O-CG 3.47Å; Q406-R410 PolarHBondContact O-N 3.29Å; Y408-R410 VanDerWaalsContact C-N 3.32Å; Y408-R410 PolarHBondContact O-N 2.8Å; R410-R413 PolarHBondContact O-N 2.73Å; R410-Q415 HydrophobicContact CG-CB 4.39Å
411	T	89.3	Confident	88.8	Confident	33 Å²	33	57.9 Å²	57.9	20%	0.202	27%	0.268	C	S	.	.	H	α-helix	trans	-71.7	-38.2	179.5	-55	0	0	0	0	110.5	H350 R353 V354 K407 Y408 R413	H350-T411 PolarHBondContact CE1-O 3.31Å; R353-T411 HydrophobicContact CB-CG2 4.47Å; V354-T411 HydrophobicContact CG2-CG2 3.92Å; K407-T411 WeakPolarHBondContact O-CB 3.45Å; K407-T411 PolarHBondContact O-N 3.07Å; K407-T411 PolarHBondContact O-OG1 3.09Å; Y408-T411 WeakPolarHBondContact O-CA 3.46Å; Y408-T411 WeakPolarHBondContact O-CB 3.39Å; Y408-T411 PolarHBondContact O-N 3.23Å; T411-R413 VanDerWaalsContact C-N 3.29Å
412	T	87.4	Confident	88.6	Confident	19 Å²	19	58.8 Å²	58.8	12%	0.117	27%	0.274	C	S	.	.	T	Hydrogen-bonded Turn	trans	-83.2	-1.3	174.5	56.6	0	0	0	0	113.8	V354 Y408 L409 Q414	V354-T412 HydrophobicContact CG1-CG2 4.18Å; V354-T412 HydrophobicContact CG2-CG2 4.46Å; Y408-T412 HydrophobicContact CD1-CG2 4.46Å; Y408-T412 HydrophobicContact CD2-CG2 4.37Å; Y408-T412 HydrophobicContact CE1-CG2 3.98Å; Y408-T412 HydrophobicContact CE2-CG2 3.89Å; Y408-T412 PolarHBondContact O-N 3.31Å; Y408-T412 PolarHBondContact O-OG1 3.47Å; L409-T412 WeakPolarHBondContact CA-OG1 3.44Å; L409-T412 PolarHBondContact O-OG1 3.49Å; T412-Q414 VanDerWaalsContact C-N 3.3Å; T412-Q414 PolarHBondContact O-N 3.01Å; T412-Q414 PolarHBondContact OG1-OE1 3.18Å
413	R	86.1	Confident	88.6	Confident	73 Å²	73	58.6 Å²	58.6	28%	0.275	27%	0.271	S	S	.	.	T	Hydrogen-bonded Turn	trans	56.4	38.2	-176.9	-57.1	-173.4	173.7	-151.1	-5.3	113.6	N291 N293 L294 A297 L409 R410 T411 Q415 H416	N291-R413 PolarHBondContact ND2-O 3.12Å; N293-R413 HydrophobicContact CB-CB 4.23Å; N293-R413 WeakPolarHBondContact O-CD 3.35Å; N293-R413 PolarHBondContact O-NH1 2.98Å; L294-R413 HydrophobicContact CD2-CB 4.37Å; A297-R413 VanDerWaalsContact CB-CZ 3.41Å; L409-R413 CarbonylContact O-C 3.55Å; L409-R413 WeakPolarHBondContact O-CA 3.45Å; L409-R413 PolarHBondContact O-N 2.77Å; R410-R413 PolarHBondContact O-N 2.73Å; T411-R413 VanDerWaalsContact C-N 3.29Å; R413-Q415 VanDerWaalsContact C-OE1 3.29Å; R413-Q415 VanDerWaalsContact CA-OE1 3.27Å; R413-H416 PolarHBondContact O-CE1 3.36Å; R413-H416 PolarHBondContact O-ND1 3.29Å
414	Q	84.4	Confident	88.5	Confident	25 Å²	25	51.5 Å²	51.5	12%	0.117	25%	0.247	C	C	.	.			trans	-105.4	2.2	179.9	-70.9	168.2	-29.1	0	0	113.3	L409 T412 H416 Y417 H418 Y444	L409-Q414 HydrophobicContact CD2-CB 3.9Å; L409-Q414 PolarHBondContact O-N 2.95Å; T412-Q414 VanDerWaalsContact C-N 3.3Å; T412-Q414 PolarHBondContact O-N 3.01Å; T412-Q414 PolarHBondContact OG1-OE1 3.18Å; Q414-H416 PolarHBondContact O-N 3.34Å; Q414-H416 VanDerWaalsContact O-N 3.09Å; Q414-Y417 HydrophobicContact CB-CD2 4.12Å; Q414-Y417 HydrophobicContact CG-CD2 4.3Å; Q414-Y417 PolarHBondContact O-N 3.12Å; Q414-H418 PolarHBondContact O-CD2 3.43Å; Q414-Y444 PolarHBondContact OE1-O 3.24Å
415	Q	84.9	Confident	88.4	Confident	90 Å²	90	56.1 Å²	56.1	42%	0.421	26%	0.264	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.6	-27.5	-174	68.5	-77.5	-5.8	0	0	114.1	L409 R410 R413 Y417	L409-Q415 PolarHBondContact O-OE1 3.24Å; R410-Q415 HydrophobicContact CG-CB 4.39Å; R413-Q415 VanDerWaalsContact C-OE1 3.29Å; R413-Q415 VanDerWaalsContact CA-OE1 3.27Å; Q415-Y417 VanDerWaalsContact C-N 3.29Å; Q415-Y417 PolarHBondContact O-N 3.47Å
416	H	82.4	Confident	88.4	Confident	57 Å²	57	57.1 Å²	57.1	26%	0.264	27%	0.269	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75	-19.8	179.9	58.3	-70.3	0	0	0	112.5	N291 R413 Q414 R457	N291-H416 PolarHBondContact OD1-CE1 3.45Å; R413-H416 PolarHBondContact O-CE1 3.36Å; R413-H416 PolarHBondContact O-ND1 3.29Å; Q414-H416 PolarHBondContact O-N 3.34Å; Q414-H416 VanDerWaalsContact O-N 3.09Å; H416-R457 PolarHBondContact O-NH1 3.3Å; H416-R457 PolarHBondContact O-NH2 3.34Å
417	Y	78.2	Confident	88.4	Confident	21 Å²	21	52.7 Å²	52.7	8%	0.082	25%	0.248	C	C	.	.	T	Hydrogen-bonded Turn	trans	-84	-19	-179.6	-61.2	-59.6	0	0	0	114.1	I289 Y290 N291 Q414 Q415 Y453	I289-Y417 HydrophobicContact CD1-CD1 3.78Å; I289-Y417 HydrophobicContact CD1-CE1 3.43Å; I289-Y417 VanDerWaalsContact CD1-CE1 3.43Å; I289-Y417 HydrophobicContact CG1-CE1 3.78Å; I289-Y417 HydrophobicContact CG2-CD2 4.5Å; I289-Y417 HydrophobicContact CG2-CE1 4.07Å; I289-Y417 HydrophobicContact CG2-CE2 4.04Å; Y290-Y417 PolarHBondContact O-OH 2.94Å; N291-Y417 WeakPolarHBondContact CA-OH 3.39Å; N291-Y417 HydrophobicContact CB-CE2 4.29Å; N291-Y417 VanDerWaalsContact CB-OH 3.23Å; N291-Y417 WeakPolarHBondContact CB-OH 3.44Å; Q414-Y417 HydrophobicContact CB-CD2 4.12Å; Q414-Y417 HydrophobicContact CG-CD2 4.3Å; Q414-Y417 PolarHBondContact O-N 3.12Å; Q415-Y417 VanDerWaalsContact C-N 3.29Å; Q415-Y417 PolarHBondContact O-N 3.47Å; Y417-Y453 HydrophobicContact CD1-CD1 4.28Å; Y417-Y453 HydrophobicContact CD1-CE1 4.48Å; Y417-Y453 HydrophobicContact CG-CD1 4.3Å; Y417-Y453 HydrophobicContact CG-CE1 4.13Å
418	H	85.3	Confident	88.4	Confident	13 Å²	13	50 Å²	50	6%	0.06	24%	0.238	C	C	.	.			trans	-125.7	104.1	-172.2	-54.1	-72.6	0	0	0	110.2	L409 Q414 I423 Y444 Y453	L409-H418 HydrophobicContact CD1-CB 4.12Å; Q414-H418 PolarHBondContact O-CD2 3.43Å; H418-I423 HydrophobicContact CB-CD1 4Å; H418-I423 HydrophobicContact CB-CG1 4.06Å; H418-Y444 HydrophobicContact CB-CE1 4.33Å; H418-Y444 AromaticContact CD2-CD1 4Å; H418-Y444 AromaticContact CE1-CD1 3.68Å; H418-Y444 AromaticContact CE1-CE1 3.88Å; H418-Y444 AromaticContact CG-CD1 3.95Å; H418-Y444 AromaticContact CG-CE1 3.83Å; H418-Y444 AromaticContact ND1-CD1 3.78Å; H418-Y444 AromaticContact ND1-CE1 3.53Å; H418-Y444 AromaticContact NE2-CD1 3.83Å; H418-Y453 AromaticContact CE1-CE1 3.84Å
419	S	87.3	Confident	88.3	Confident	59 Å²	59	54.9 Å²	54.9	41%	0.413	26%	0.26	S	S	.	.			trans	-74.3	157.6	167.9	67.9	0	0	0	0	110.3	E421 S422 I423	S419-E421 VanDerWaalsContact C-N 3.25Å; S419-E421 PolarHBondContact O-N 2.99Å; S419-S422 PolarHBondContact O-N 3.25Å; S419-S422 VanDerWaalsContact OG-CB 3.26Å; S419-S422 WeakPolarHBondContact OG-CB 3.37Å; S419-S422 PolarHBondContact OG-N 3.39Å; S419-S422 VanDerWaalsContact OG-N 3.1Å; S419-I423 WeakPolarHBondContact O-CD1 3.42Å; S419-I423 VanDerWaalsContact O-CG1 3.29Å; S419-I423 WeakPolarHBondContact O-CG1 3.36Å; S419-I423 PolarHBondContact O-N 3.41Å; S419-I423 VanDerWaalsContact O-N 3.08Å
420	M	88.7	Confident	88.4	Confident	120 Å²	120	54.6 Å²	54.6	59%	0.591	26%	0.258	S	S	*	.	H	α-helix	trans	-58.1	-41.4	174.9	175.6	170.3	160.2	0	0	111.5	F398 I423 L424	F398-M420 HydrophobicContact CD1-CE 4.35Å; F398-M420 HydrophobicContact CE1-CE 4.1Å; F398-M420 HydrophobicContact CE1-CG 3.89Å; F398-M420 HydrophobicContact CE1-SD 4.09Å; F398-M420 HydrophobicContact CZ-CG 4.23Å; M420-I423 PolarHBondContact O-N 2.99Å; M420-L424 HydrophobicContact CE-CD1 3.91Å; M420-L424 HydrophobicContact CG-CD1 4.13Å; M420-L424 WeakPolarHBondContact O-CG 3.44Å; M420-L424 PolarHBondContact O-N 3.14Å
421	E	88.4	Confident	88.5	Confident	153 Å²	153	47.5 Å²	47.5	72%	0.715	23%	0.233	S	C	*	.	H	α-helix	trans	-63.1	-44.5	178.1	-173.8	170.9	-166.7	0	0	112.3	S419 I423 L424 Q425	S419-E421 VanDerWaalsContact C-N 3.25Å; S419-E421 PolarHBondContact O-N 2.99Å; E421-I423 VanDerWaalsContact C-N 3.29Å; E421-I423 PolarHBondContact O-N 3.29Å; E421-L424 PolarHBondContact O-N 3.39Å; E421-Q425 WeakPolarHBondContact O-CB 3.35Å; E421-Q425 PolarHBondContact O-N 3.06Å
422	S	88.1	Confident	88.5	Confident	18 Å²	18	50.3 Å²	50.3	13%	0.126	25%	0.25	C	C	.	.	H	α-helix	trans	-61.9	-37.5	175.9	-178.9	0	0	0	0	112.1	S419 H426	S419-S422 PolarHBondContact O-N 3.25Å; S419-S422 VanDerWaalsContact OG-CB 3.26Å; S419-S422 WeakPolarHBondContact OG-CB 3.37Å; S419-S422 PolarHBondContact OG-N 3.39Å; S419-S422 VanDerWaalsContact OG-N 3.1Å; S422-H426 WeakPolarHBondContact O-CB 3.37Å; S422-H426 PolarHBondContact O-N 3.01Å
423	I	91	Very high	88.7	Confident	10 Å²	10	53.9 Å²	53.9	5%	0.051	27%	0.268	C	S	.	.	H	α-helix	trans	-67.8	-45	176.2	-63.5	160.7	0	0	0	111.1	F398 L405 L409 H418 S419 M420 E421 H426 L427 F440 Y444	F398-I423 HydrophobicContact CD2-CG2 4.16Å; F398-I423 HydrophobicContact CE2-CB 4.38Å; F398-I423 HydrophobicContact CE2-CG2 3.58Å; F398-I423 HydrophobicContact CZ-CG2 4.44Å; L405-I423 HydrophobicContact CD2-CD1 3.95Å; L405-I423 HydrophobicContact CD2-CG1 4.39Å; L405-I423 HydrophobicContact CD2-CG2 3.78Å; L409-I423 HydrophobicContact CD1-CD1 4.48Å; H418-I423 HydrophobicContact CB-CD1 4Å; H418-I423 HydrophobicContact CB-CG1 4.06Å; S419-I423 WeakPolarHBondContact O-CD1 3.42Å; S419-I423 VanDerWaalsContact O-CG1 3.29Å; S419-I423 WeakPolarHBondContact O-CG1 3.36Å; S419-I423 PolarHBondContact O-N 3.41Å; S419-I423 VanDerWaalsContact O-N 3.08Å; M420-I423 PolarHBondContact O-N 2.99Å; E421-I423 VanDerWaalsContact C-N 3.29Å; E421-I423 PolarHBondContact O-N 3.29Å; I423-H426 PolarHBondContact O-N 3.09Å; I423-L427 WeakPolarHBondContact O-CB 3.31Å; I423-L427 PolarHBondContact O-N 2.86Å; I423-F440 HydrophobicContact CG2-CE2 4.46Å; I423-F440 HydrophobicContact CG2-CZ 4.1Å; I423-Y444 WeakPolarHBondContact CA-OH 3.48Å; I423-Y444 HydrophobicContact CG1-CE1 3.92Å
424	L	91.7	Very high	88.8	Confident	28 Å²	28	53.6 Å²	53.6	15%	0.147	29%	0.288	C	S	.	.	H	α-helix	trans	-64.4	-40.4	177.6	-74.4	173.5	0	0	0	111.9	Q395 F398 M420 E421 L427 A428	Q395-L424 HydrophobicContact CG-CD1 4.33Å; Q395-L424 HydrophobicContact CG-CD2 4.33Å; F398-L424 HydrophobicContact CB-CD2 3.6Å; F398-L424 HydrophobicContact CD1-CD2 4Å; F398-L424 HydrophobicContact CD2-CD2 4.19Å; F398-L424 HydrophobicContact CG-CD2 3.67Å; M420-L424 HydrophobicContact CE-CD1 3.91Å; M420-L424 HydrophobicContact CG-CD1 4.13Å; M420-L424 WeakPolarHBondContact O-CG 3.44Å; M420-L424 PolarHBondContact O-N 3.14Å; E421-L424 PolarHBondContact O-N 3.39Å; L424-L427 PolarHBondContact O-N 2.86Å; L424-A428 WeakPolarHBondContact O-CB 3.45Å; L424-A428 PolarHBondContact O-N 3.39Å
425	Q	91.6	Very high	89.2	Confident	117 Å²	117	55 Å²	55	55%	0.547	30%	0.295	S	S	.	.	H	α-helix	trans	-63.5	-42.9	175.8	-173.5	-179.9	7.4	0	0	111.7	E421 F429	E421-Q425 WeakPolarHBondContact O-CB 3.35Å; E421-Q425 PolarHBondContact O-N 3.06Å; Q425-F429 WeakPolarHBondContact O-CB 3.27Å; Q425-F429 PolarHBondContact O-N 3.38Å
426	H	91.4	Very high	89.6	Confident	23 Å²	23	54.6 Å²	54.6	11%	0.106	30%	0.299	C	S	.	.	H	α-helix	trans	-64.4	-42.4	174.7	-171.7	62.1	0	0	0	111.7	S422 I423 F429 C430 F440 R443	S422-H426 WeakPolarHBondContact O-CB 3.37Å; S422-H426 PolarHBondContact O-N 3.01Å; I423-H426 PolarHBondContact O-N 3.09Å; H426-F429 WeakPolarHBondContact O-CB 3.34Å; H426-F429 PolarHBondContact O-N 3.41Å; H426-C430 PolarHBondContact O-N 3.18Å; H426-C430 PolarHBondContact O-SG 3.13Å; H426-F440 AromaticContact CD2-CD2 3.45Å; H426-F440 VanDerWaalsContact CD2-CD2 3.45Å; H426-F440 WeakPolarHBondContact CD2-CD2 3.37Å; H426-F440 AromaticContact CD2-CE2 3.73Å; H426-F440 PolarHBondContact NE2-O 3.28Å; H426-R443 PolarHBondContact ND1-NH1 3.3Å
427	L	92.9	Very high	90.1	Very high	0 Å²	0	53.1 Å²	53.1	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-63.3	-45.4	177.6	-175.2	60.1	0	0	0	111.7	F369 A394 I397 F398 M401 I423 L424 F429 C430 I431 F440	F369-L427 HydrophobicContact CE2-CD1 3.74Å; F369-L427 HydrophobicContact CZ-CD1 3.83Å; A394-L427 HydrophobicContact CB-CB 4.08Å; A394-L427 HydrophobicContact CB-CD2 3.89Å; A394-L427 HydrophobicContact CB-CG 3.82Å; A394-L427 WeakPolarHBondContact O-CD2 3.48Å; I397-L427 HydrophobicContact CD1-CD1 3.96Å; I397-L427 HydrophobicContact CD1-CD2 3.73Å; I397-L427 HydrophobicContact CD1-CG 4.17Å; I397-L427 HydrophobicContact CG1-CD2 4.11Å; F398-L427 HydrophobicContact CB-CD2 4.28Å; M401-L427 HydrophobicContact CE-CD1 4.47Å; M401-L427 HydrophobicContact SD-CD2 4.4Å; I423-L427 WeakPolarHBondContact O-CB 3.31Å; I423-L427 PolarHBondContact O-N 2.86Å; L424-L427 PolarHBondContact O-N 2.86Å; L427-F429 VanDerWaalsContact C-N 3.33Å; L427-F429 PolarHBondContact O-N 3Å; L427-C430 WeakPolarHBondContact O-CB 3.38Å; L427-C430 PolarHBondContact O-N 3.27Å; L427-C430 VanDerWaalsContact O-N 3.17Å; L427-I431 HydrophobicContact CG-CD1 4.24Å; L427-I431 VanDerWaalsContact O-CG1 3.3Å; L427-I431 WeakPolarHBondContact O-CG1 3.36Å; L427-I431 PolarHBondContact O-N 3.33Å; L427-F440 HydrophobicContact CB-CD2 4.32Å; L427-F440 HydrophobicContact CB-CE2 3.79Å; L427-F440 HydrophobicContact CD1-CD2 3.87Å; L427-F440 HydrophobicContact CD1-CE2 3.82Å; L427-F440 HydrophobicContact CD1-CG 4.33Å; L427-F440 HydrophobicContact CD1-CZ 4.22Å; L427-F440 HydrophobicContact CG-CE2 4.37Å
428	A	92.3	Very high	90.8	Very high	7 Å²	7	59.3 Å²	59.3	6%	0.058	32%	0.322	C	S	.	.	H	α-helix	trans	-59	-45.2	173.7	0	0	0	0	0	111	R391 A394 L424 C430 I431 T432	R391-A428 HydrophobicContact CG-CB 3.92Å; A394-A428 HydrophobicContact CB-CB 4.08Å; L424-A428 WeakPolarHBondContact O-CB 3.45Å; L424-A428 PolarHBondContact O-N 3.39Å; A428-C430 VanDerWaalsContact C-N 3.32Å; A428-C430 PolarHBondContact O-N 3.32Å; A428-I431 PolarHBondContact O-N 2.96Å; A428-I431 VanDerWaalsContact O-N 3.14Å; A428-T432 PolarHBondContact O-N 3.23Å; A428-T432 PolarHBondContact O-OG1 3.16Å
429	F	92.4	Very high	91	Very high	114 Å²	114	60.3 Å²	60.3	50%	0.5	33%	0.332	S	S	.	.	H	α-helix	trans	-59.8	-39.6	174.7	178.9	-97.2	0	0	0	112.6	Q425 H426 L427 N433 M435	Q425-F429 WeakPolarHBondContact O-CB 3.27Å; Q425-F429 PolarHBondContact O-N 3.38Å; H426-F429 WeakPolarHBondContact O-CB 3.34Å; H426-F429 PolarHBondContact O-N 3.41Å; L427-F429 VanDerWaalsContact C-N 3.33Å; L427-F429 PolarHBondContact O-N 3Å; F429-N433 WeakPolarHBondContact CD2-ND2 3.45Å; F429-N433 WeakPolarHBondContact CE2-ND2 3.27Å; F429-N433 WeakPolarHBondContact CZ-ND2 3.39Å; F429-N433 PolarHBondContact O-N 2.94Å; F429-N433 PolarHBondContact O-ND2 3.47Å; F429-M435 HydrophobicContact CD1-CE 3.33Å; F429-M435 HydrophobicContact CE1-CE 3.37Å; F429-M435 HydrophobicContact CE1-SD 4.46Å; F429-M435 HydrophobicContact CG-CE 4.48Å
430	C	93.1	Very high	91.3	Very high	0 Å²	0	57.5 Å²	57.5	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-62	-43	173.2	-65.6	0	0	0	0	112.7	F369 H426 L427 A428 G434 M435 F440	F369-C430 HydrophobicContact CE1-CB 4.47Å; F369-C430 HydrophobicContact CZ-CB 4.17Å; H426-C430 PolarHBondContact O-N 3.18Å; H426-C430 PolarHBondContact O-SG 3.13Å; L427-C430 WeakPolarHBondContact O-CB 3.38Å; L427-C430 PolarHBondContact O-N 3.27Å; L427-C430 VanDerWaalsContact O-N 3.17Å; A428-C430 VanDerWaalsContact C-N 3.32Å; A428-C430 PolarHBondContact O-N 3.32Å; C430-G434 PolarHBondContact O-N 3.23Å; C430-M435 VanDerWaalsContact CA-CE 3.47Å; C430-M435 HydrophobicContact CB-CB 4.13Å; C430-M435 HydrophobicContact CB-CE 3.99Å; C430-M435 PolarHBondContact O-N 3.2Å; C430-M435 VanDerWaalsContact SG-CE 3.51Å; C430-F440 HydrophobicContact CB-CB 4.43Å
431	I	90.5	Very high	91.5	Very high	18 Å²	18	52 Å²	52	9%	0.092	29%	0.285	C	S	.	.	H	α-helix	trans	-66.5	-47.6	179.5	-65	166.1	0	0	0	110.3	I372 P390 A393 A394 L427 A428 N433 G434	I372-I431 HydrophobicContact CD1-CD1 3.67Å; I372-I431 HydrophobicContact CD1-CG1 3.72Å; I372-I431 HydrophobicContact CG2-CG2 4.44Å; P390-I431 HydrophobicContact CB-CG2 4.32Å; A393-I431 HydrophobicContact CB-CD1 4.08Å; A394-I431 HydrophobicContact CB-CD1 3.95Å; L427-I431 HydrophobicContact CG-CD1 4.24Å; L427-I431 VanDerWaalsContact O-CG1 3.3Å; L427-I431 WeakPolarHBondContact O-CG1 3.36Å; L427-I431 PolarHBondContact O-N 3.33Å; A428-I431 PolarHBondContact O-N 2.96Å; A428-I431 VanDerWaalsContact O-N 3.14Å; I431-N433 VanDerWaalsContact C-N 3.26Å; I431-N433 PolarHBondContact O-N 2.87Å; I431-G434 PolarHBondContact O-N 3.19Å; I431-G434 VanDerWaalsContact O-N 3.14Å
432	T	90.6	Very high	91.6	Very high	91 Å²	91	48.4 Å²	48.4	56%	0.558	27%	0.269	S	S	*	.	H	α-helix	trans	-57.5	-38	179.7	-55	0	0	0	0	112.6	P390 A428	P390-T432 VanDerWaalsContact CB-OG1 3.28Å; P390-T432 WeakPolarHBondContact CB-OG1 3.48Å; A428-T432 PolarHBondContact O-N 3.23Å; A428-T432 PolarHBondContact O-OG1 3.16Å
433	N	91.4	Very high	91.5	Very high	94 Å²	94	50.1 Å²	50.1	50%	0.503	27%	0.272	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.4	9.2	-177.6	-65.6	-77.9	0	0	0	113.6	F429 I431 M435	F429-N433 WeakPolarHBondContact CD2-ND2 3.45Å; F429-N433 WeakPolarHBondContact CE2-ND2 3.27Å; F429-N433 WeakPolarHBondContact CZ-ND2 3.39Å; F429-N433 PolarHBondContact O-N 2.94Å; F429-N433 PolarHBondContact O-ND2 3.47Å; I431-N433 VanDerWaalsContact C-N 3.26Å; I431-N433 PolarHBondContact O-N 2.87Å; N433-M435 HydrophobicContact CB-CG 3.99Å; N433-M435 PolarHBondContact O-N 2.81Å
434	G	88.9	Confident	91.4	Very high	67 Å²	67	49.7 Å²	49.7	69%	0.691	27%	0.27	S	S	*	.	T	Hydrogen-bonded Turn	trans	60.4	30.2	-179.8	0	0	0	0	0	114	C430 I431	C430-G434 PolarHBondContact O-N 3.23Å; I431-G434 PolarHBondContact O-N 3.19Å; I431-G434 VanDerWaalsContact O-N 3.14Å
435	M	92.3	Very high	91.2	Very high	55 Å²	55	50.2 Å²	50.2	27%	0.271	27%	0.273	S	S	.	.			trans	-74	150.7	-176.6	-66.3	-157.9	-77.8	0	0	112.2	F369 F429 C430 N433 A439	F369-M435 WeakPolarHBondContact CE1-O 3.33Å; F429-M435 HydrophobicContact CD1-CE 3.33Å; F429-M435 HydrophobicContact CE1-CE 3.37Å; F429-M435 HydrophobicContact CE1-SD 4.46Å; F429-M435 HydrophobicContact CG-CE 4.48Å; C430-M435 VanDerWaalsContact CA-CE 3.47Å; C430-M435 HydrophobicContact CB-CB 4.13Å; C430-M435 HydrophobicContact CB-CE 3.99Å; C430-M435 PolarHBondContact O-N 3.2Å; C430-M435 VanDerWaalsContact SG-CE 3.51Å; N433-M435 HydrophobicContact CB-CG 3.99Å; N433-M435 PolarHBondContact O-N 2.81Å; M435-A439 HydrophobicContact CB-CB 4.04Å; M435-A439 HydrophobicContact SD-CB 4.32Å
436	T	93.3	Very high	90.7	Very high	81 Å²	81	49.4 Å²	49.4	50%	0.497	27%	0.271	S	S	.	.			trans	-74.6	160.3	179.9	65.1	0	0	0	0	112.5	K438 A439 F440	T436-K438 PolarHBondContact O-N 2.84Å; T436-K438 VanDerWaalsContact O-N 3.14Å; T436-A439 WeakPolarHBondContact O-CB 3.43Å; T436-A439 PolarHBondContact O-N 3.33Å; T436-A439 PolarHBondContact OG1-N 2.87Å; T436-F440 PolarHBondContact O-N 3.48Å; T436-F440 VanDerWaalsContact O-N 3.16Å
437	P	92.7	Very high	89.7	Confident	27 Å²	27	50 Å²	50	18%	0.175	28%	0.28	C	S	.	.	H	α-helix	trans	-51.3	-37.1	172.2	-28.3	34.8	0	0	0	113.3	V365 E366 F369 F440 L441	V365-P437 HydrophobicContact CG1-CB 3.97Å; E366-P437 HydrophobicContact CG-CB 4Å; E366-P437 HydrophobicContact CG-CG 4.31Å; F369-P437 HydrophobicContact CB-CG 3.61Å; F369-P437 HydrophobicContact CD1-CG 4.09Å; F369-P437 HydrophobicContact CD2-CB 4.34Å; F369-P437 HydrophobicContact CD2-CG 4.25Å; F369-P437 HydrophobicContact CG-CB 4.31Å; F369-P437 HydrophobicContact CG-CG 3.73Å; P437-F440 PolarHBondContact O-N 3Å; P437-L441 WeakPolarHBondContact O-CB 3.5Å; P437-L441 VanDerWaalsContact O-CG 3.31Å; P437-L441 WeakPolarHBondContact O-CG 3.38Å; P437-L441 PolarHBondContact O-N 3.18Å
438	K	92	Very high	88.6	Confident	150 Å²	150	50.2 Å²	50.2	65%	0.652	28%	0.283	S	S	*	.	H	α-helix	trans	-67.1	-38.4	179	-67.5	-178.3	179.9	174.3	0	111.9	T436 L441 E442	T436-K438 PolarHBondContact O-N 2.84Å; T436-K438 VanDerWaalsContact O-N 3.14Å; K438-L441 PolarHBondContact O-N 2.86Å; K438-E442 PolarHBondContact O-N 3.28Å
439	A	91.1	Very high	87.8	Confident	34 Å²	34	51.7 Å²	51.7	28%	0.281	29%	0.291	S	S	.	.	H	α-helix	trans	-68.2	-37.2	176.4	0	0	0	0	0	112	M435 T436 L441 E442	M435-A439 HydrophobicContact CB-CB 4.04Å; M435-A439 HydrophobicContact SD-CB 4.32Å; T436-A439 WeakPolarHBondContact O-CB 3.43Å; T436-A439 PolarHBondContact O-N 3.33Å; T436-A439 PolarHBondContact OG1-N 2.87Å; A439-L441 VanDerWaalsContact C-N 3.35Å; A439-E442 WeakPolarHBondContact O-CB 3.4Å
440	F	92.6	Very high	86.7	Confident	0 Å²	0	46.6 Å²	46.6	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-61	-45	170.1	170.8	-102.9	0	0	0	111.7	V365 F369 M401 I423 H426 L427 C430 T436 P437 E442 Y444	V365-F440 HydrophobicContact CG1-CD1 3.72Å; V365-F440 HydrophobicContact CG1-CE1 4.28Å; V365-F440 HydrophobicContact CG2-CD1 4.29Å; V365-F440 HydrophobicContact CG2-CE1 4.13Å; F369-F440 HydrophobicContact CE2-CB 4.13Å; F369-F440 HydrophobicContact CE2-CD1 4.35Å; F369-F440 HydrophobicContact CE2-CG 4.24Å; F369-F440 HydrophobicContact CZ-CB 3.83Å; F369-F440 HydrophobicContact CZ-CG 4.26Å; M401-F440 HydrophobicContact SD-CE1 3.85Å; M401-F440 HydrophobicContact SD-CZ 4.1Å; I423-F440 HydrophobicContact CG2-CE2 4.46Å; I423-F440 HydrophobicContact CG2-CZ 4.1Å; H426-F440 AromaticContact CD2-CD2 3.45Å; H426-F440 VanDerWaalsContact CD2-CD2 3.45Å; H426-F440 WeakPolarHBondContact CD2-CD2 3.37Å; H426-F440 AromaticContact CD2-CE2 3.73Å; H426-F440 PolarHBondContact NE2-O 3.28Å; L427-F440 HydrophobicContact CB-CD2 4.32Å; L427-F440 HydrophobicContact CB-CE2 3.79Å; L427-F440 HydrophobicContact CD1-CD2 3.87Å; L427-F440 HydrophobicContact CD1-CE2 3.82Å; L427-F440 HydrophobicContact CD1-CG 4.33Å; L427-F440 HydrophobicContact CD1-CZ 4.22Å; L427-F440 HydrophobicContact CG-CE2 4.37Å; C430-F440 HydrophobicContact CB-CB 4.43Å; T436-F440 PolarHBondContact O-N 3.48Å; T436-F440 VanDerWaalsContact O-N 3.16Å; P437-F440 PolarHBondContact O-N 3Å; F440-E442 VanDerWaalsContact C-N 3.33Å; F440-E442 PolarHBondContact O-N 3.36Å; F440-Y444 HydrophobicContact CD1-CE2 4.35Å; F440-Y444 HydrophobicContact CD2-CE2 4.26Å; F440-Y444 HydrophobicContact CE1-CD2 4.39Å; F440-Y444 AromaticContact CE1-CE2 3.87Å; F440-Y444 HydrophobicContact CE1-CE2 3.87Å; F440-Y444 AromaticContact CE2-CE2 3.74Å; F440-Y444 HydrophobicContact CE2-CE2 3.74Å; F440-Y444 HydrophobicContact CZ-CD2 4.46Å; F440-Y444 AromaticContact CZ-CE2 3.53Å; F440-Y444 HydrophobicContact CZ-CE2 3.53Å; F440-Y444 WeakPolarHBondContact O-CE2 3.36Å
441	L	93.1	Very high	85.6	Confident	4 Å²	4	51 Å²	51	2%	0.021	29%	0.293	C	S	.	.	H	α-helix	trans	-71	-22.9	-177.2	-74.9	173.5	0	0	0	114.6	L361 V362 V365 P437 K438 A439 R443 Y444 L445	L361-L441 HydrophobicContact CD1-CD2 4.07Å; L361-L441 HydrophobicContact CD2-CD2 3.83Å; L361-L441 HydrophobicContact CG-CD2 3.65Å; V362-L441 HydrophobicContact CB-CD1 4.33Å; V362-L441 HydrophobicContact CG2-CD1 3.94Å; V365-L441 HydrophobicContact CB-CD1 4.15Å; V365-L441 HydrophobicContact CB-CD2 4.35Å; V365-L441 HydrophobicContact CB-CG 4.31Å; V365-L441 HydrophobicContact CG1-CD1 4.32Å; V365-L441 HydrophobicContact CG1-CG 4.16Å; V365-L441 HydrophobicContact CG2-CD1 4.47Å; V365-L441 HydrophobicContact CG2-CD2 3.81Å; V365-L441 HydrophobicContact CG2-CG 4.28Å; P437-L441 WeakPolarHBondContact O-CB 3.5Å; P437-L441 VanDerWaalsContact O-CG 3.31Å; P437-L441 WeakPolarHBondContact O-CG 3.38Å; P437-L441 PolarHBondContact O-N 3.18Å; K438-L441 PolarHBondContact O-N 2.86Å; A439-L441 VanDerWaalsContact C-N 3.35Å; L441-R443 VanDerWaalsContact C-N 3.27Å; L441-R443 PolarHBondContact O-N 3.39Å; L441-Y444 PolarHBondContact O-N 3.17Å; L441-L445 HydrophobicContact CB-CD1 3.78Å; L441-L445 HydrophobicContact CB-CG 4.15Å; L441-L445 HydrophobicContact CD1-CD1 4.35Å; L441-L445 HydrophobicContact CG-CD1 4.48Å; L441-L445 WeakPolarHBondContact O-CB 3.23Å; L441-L445 WeakPolarHBondContact O-CG 3.37Å; L441-L445 PolarHBondContact O-N 2.94Å
442	E	90.5	Very high	84.5	Confident	78 Å²	78	53.3 Å²	53.3	36%	0.364	30%	0.303	S	S	.	.	H	α-helix	trans	-48.8	-49.6	-179.8	-174.2	-80.9	156.3	0	0	111.3	K438 A439 F440 Y444 L445 I446	K438-E442 PolarHBondContact O-N 3.28Å; A439-E442 WeakPolarHBondContact O-CB 3.4Å; F440-E442 VanDerWaalsContact C-N 3.33Å; F440-E442 PolarHBondContact O-N 3.36Å; E442-Y444 PolarHBondContact O-N 3.01Å; E442-L445 PolarHBondContact O-N 3.37Å; E442-I446 HydrophobicContact CG-CD1 4.28Å; E442-I446 PolarHBondContact O-N 3.08Å
443	R	87.1	Confident	83.6	Confident	55 Å²	55	49.6 Å²	49.6	21%	0.208	28%	0.279	C	S	.	.	H	α-helix	trans	-58.3	-23.4	-179.5	-170.7	170.7	-171.1	178.3	2.7	115.3	H426 L441 Q452	H426-R443 PolarHBondContact ND1-NH1 3.3Å; L441-R443 VanDerWaalsContact C-N 3.27Å; L441-R443 PolarHBondContact O-N 3.39Å; R443-Q452 PolarHBondContact NH2-O 3.42Å
444	Y	88.3	Confident	82.4	Confident	1 Å²	1	50.1 Å²	50.1	0%	0.004	28%	0.282	C	S	.	.	H	α-helix	trans	-107.7	-31.7	-177.5	-51	-72.2	0	0	0	112.5	L405 Y408 L409 Q414 H418 I423 F440 L441 E442	L405-Y444 HydrophobicContact CD1-CD1 4.26Å; L405-Y444 HydrophobicContact CD1-CD2 4.19Å; L405-Y444 HydrophobicContact CD1-CG 3.97Å; Y408-Y444 WeakPolarHBondContact CE1-O 3.35Å; L409-Y444 HydrophobicContact CD2-CD1 4.28Å; Q414-Y444 PolarHBondContact OE1-O 3.24Å; H418-Y444 HydrophobicContact CB-CE1 4.33Å; H418-Y444 AromaticContact CD2-CD1 4Å; H418-Y444 AromaticContact CE1-CD1 3.68Å; H418-Y444 AromaticContact CE1-CE1 3.88Å; H418-Y444 AromaticContact CG-CD1 3.95Å; H418-Y444 AromaticContact CG-CE1 3.83Å; H418-Y444 AromaticContact ND1-CD1 3.78Å; H418-Y444 AromaticContact ND1-CE1 3.53Å; H418-Y444 AromaticContact NE2-CD1 3.83Å; I423-Y444 WeakPolarHBondContact CA-OH 3.48Å; I423-Y444 HydrophobicContact CG1-CE1 3.92Å; F440-Y444 HydrophobicContact CD1-CE2 4.35Å; F440-Y444 HydrophobicContact CD2-CE2 4.26Å; F440-Y444 HydrophobicContact CE1-CD2 4.39Å; F440-Y444 AromaticContact CE1-CE2 3.87Å; F440-Y444 HydrophobicContact CE1-CE2 3.87Å; F440-Y444 AromaticContact CE2-CE2 3.74Å; F440-Y444 HydrophobicContact CE2-CE2 3.74Å; F440-Y444 HydrophobicContact CZ-CD2 4.46Å; F440-Y444 AromaticContact CZ-CE2 3.53Å; F440-Y444 HydrophobicContact CZ-CE2 3.53Å; F440-Y444 WeakPolarHBondContact O-CE2 3.36Å; L441-Y444 PolarHBondContact O-N 3.17Å; E442-Y444 PolarHBondContact O-N 3.01Å
445	L	88.1	Confident	81.2	Confident	39 Å²	39	53 Å²	53	20%	0.204	28%	0.275	C	S	.	.	H	α-helix	trans	-85.1	-30.6	-177	-64.4	-176.3	0	0	0	112.4	K358 L361 V362 Y408 L441 E442	K358-L445 HydrophobicContact CD-CD2 4.36Å; K358-L445 HydrophobicContact CG-CD1 4.47Å; K358-L445 HydrophobicContact CG-CD2 3.89Å; L361-L445 HydrophobicContact CD2-CD2 4.21Å; V362-L445 HydrophobicContact CG2-CD1 4.34Å; Y408-L445 HydrophobicContact CD1-CD2 4.4Å; Y408-L445 HydrophobicContact CE1-CD2 3.71Å; Y408-L445 HydrophobicContact CE2-CD2 4.03Å; Y408-L445 VanDerWaalsContact CZ-CD2 3.48Å; Y408-L445 WeakPolarHBondContact OH-CD2 3.26Å; L441-L445 HydrophobicContact CB-CD1 3.78Å; L441-L445 HydrophobicContact CB-CG 4.15Å; L441-L445 HydrophobicContact CD1-CD1 4.35Å; L441-L445 HydrophobicContact CG-CD1 4.48Å; L441-L445 WeakPolarHBondContact O-CB 3.23Å; L441-L445 WeakPolarHBondContact O-CG 3.37Å; L441-L445 PolarHBondContact O-N 2.94Å; E442-L445 PolarHBondContact O-N 3.37Å
446	I	80.1	Confident	79.9	Confident	100 Å²	100	57 Å²	57	51%	0.513	30%	0.298	S	S	.	.	S	Bend	trans	-110.9	121.5	176.7	-54.1	-178.5	0	0	0	106.2	E442 G448	E442-I446 HydrophobicContact CG-CD1 4.28Å; E442-I446 PolarHBondContact O-N 3.08Å; I446-G448 VanDerWaalsContact C-N 3.3Å; I446-G448 PolarHBondContact O-N 2.85Å
447	A	71.1	Confident	78.4	Confident	35 Å²	35	58.5 Å²	58.5	29%	0.289	29%	0.294	S	S	.	.			trans	-69.2	95.8	172.1	0	0	0	0	0	107.4	T288	T288-A447 HydrophobicContact CG2-CB 4Å; T288-A447 WeakPolarHBondContact CG2-O 3.48Å
448	G	69.8	Low	77	Confident	5 Å²	5	59.9 Å²	59.9	5%	0.052	30%	0.296	C	S	.	.			trans	-70.9	177	178.3	0	0	0	0	0	112.5	I446 Q452	I446-G448 VanDerWaalsContact C-N 3.3Å; I446-G448 PolarHBondContact O-N 2.85Å; G448-Q452 VanDerWaalsContact CA-OE1 3.32Å
449	P	75.9	Confident	75.3	Confident	37 Å²	37	57 Å²	57	24%	0.24	29%	0.287	C	S	.	.	B	Isolated β-bridge	trans	-62.9	155.5	-174.4	22.1	-32.5	0	0	0	113.6	Y284 K285 F287 L451 Q452	Y284-P449 WeakPolarHBondContact O-CB 3.36Å; K285-P449 WeakPolarHBondContact O-CB 3.46Å; F287-P449 WeakPolarHBondContact O-CA 3.43Å; P449-L451 PolarHBondContact O-N 3.38Å; P449-Q452 HydrophobicContact CG-CG 4.04Å; P449-Q452 WeakPolarHBondContact O-CB 3.25Å; P449-Q452 PolarHBondContact O-N 3.1Å
450	T	68.2	Low	73.4	Confident	7 Å²	7	59 Å²	59	4%	0.043	30%	0.299	C	S	.	.	G	3₁₀ helix	trans	-49.1	-34.2	-177.2	-57.3	0	0	0	0	112.9	Y284 F287 Q452 Y453 W458	Y284-T450 HydrophobicContact CD1-CG2 3.89Å; Y284-T450 HydrophobicContact CE1-CG2 4.22Å; F287-T450 PolarHBondContact O-N 3.42Å; T450-Q452 VanDerWaalsContact C-N 3.28Å; T450-Q452 PolarHBondContact O-N 3.18Å; T450-Y453 PolarHBondContact O-N 3.32Å; T450-W458 HydrophobicContact CG2-CB 3.43Å; T450-W458 VanDerWaalsContact CG2-CB 3.43Å; T450-W458 HydrophobicContact CG2-CG 4.07Å
451	L	69.3	Low	71.9	Confident	94 Å²	94	59.9 Å²	59.9	49%	0.492	31%	0.305	S	S	.	.	G	3₁₀ helix	trans	-65.8	-18.4	178.5	-70.3	166.5	0	0	0	115.5	Y284 P449 Y453 W458	Y284-L451 WeakPolarHBondContact O-CG 3.3Å; P449-L451 PolarHBondContact O-N 3.38Å; L451-Y453 PolarHBondContact O-N 3.05Å; L451-W458 HydrophobicContact CD2-CH2 3.76Å; L451-W458 HydrophobicContact CD2-CZ2 3.75Å; L451-W458 HydrophobicContact CD2-CZ3 4.17Å
452	Q	68.9	Low	71.1	Confident	65 Å²	65	68.3 Å²	68.3	30%	0.304	34%	0.344	S	S	.	.	G	3₁₀ helix	trans	-73.6	-8.7	179.5	-68.1	-173.9	-9.4	0	0	113.8	R443 G448 P449 T450	R443-Q452 PolarHBondContact NH2-O 3.42Å; G448-Q452 VanDerWaalsContact CA-OE1 3.32Å; P449-Q452 HydrophobicContact CG-CG 4.04Å; P449-Q452 WeakPolarHBondContact O-CB 3.25Å; P449-Q452 PolarHBondContact O-N 3.1Å; T450-Q452 VanDerWaalsContact C-N 3.28Å; T450-Q452 PolarHBondContact O-N 3.18Å
453	Y	70.6	Confident	71	Confident	13 Å²	13	66.7 Å²	66.7	5%	0.051	34%	0.335	C	S	.	.	S	Bend	trans	-109.3	158.3	-176.7	-56.9	-88	0	0	0	110.7	I289 Y417 H418 T450 L451 W458	I289-Y453 HydrophobicContact CB-CD2 4.03Å; I289-Y453 HydrophobicContact CB-CE2 3.86Å; I289-Y453 HydrophobicContact CD1-CD1 4.25Å; I289-Y453 HydrophobicContact CD1-CD2 3.56Å; I289-Y453 HydrophobicContact CD1-CE2 4.16Å; I289-Y453 HydrophobicContact CD1-CG 3.61Å; I289-Y453 HydrophobicContact CG1-CD2 4.39Å; I289-Y453 HydrophobicContact CG2-CD2 4.22Å; I289-Y453 HydrophobicContact CG2-CE2 3.67Å; Y417-Y453 HydrophobicContact CD1-CD1 4.28Å; Y417-Y453 HydrophobicContact CD1-CE1 4.48Å; Y417-Y453 HydrophobicContact CG-CD1 4.3Å; Y417-Y453 HydrophobicContact CG-CE1 4.13Å; H418-Y453 AromaticContact CE1-CE1 3.84Å; T450-Y453 PolarHBondContact O-N 3.32Å; L451-Y453 PolarHBondContact O-N 3.05Å; Y453-W458 VanDerWaalsContact O-CD1 3.3Å; Y453-W458 PolarHBondContact O-NE1 3.35Å; Y453-W458 VanDerWaalsContact O-NE1 3.12Å
454	D	67.1	Low	71.2	Confident	106 Å²	106	72.4 Å²	72.4	57%	0.567	36%	0.356	S	S	*	.			trans	-51.6	142.6	-174.7	-87.1	-40.8	0	0	0	113.8	D456 R457	D454-D456 PolarHBondContact O-N 3.41Å; D454-R457 HydrophobicContact CB-CG 4.5Å; D454-R457 WeakPolarHBondContact O-CB 3.33Å; D454-R457 PolarHBondContact O-N 2.99Å
455	K	62.7	Low	71.4	Confident	126 Å²	126	74.8 Å²	74.8	55%	0.548	37%	0.369	S	S	.	.	H	α-helix	trans	-48.8	-47	-176.9	-157.5	177.5	-176.8	-177.4	0	111.7	R457 W458 L459	K455-R457 PolarHBondContact O-N 3.21Å; K455-W458 HydrophobicContact CG-CZ2 4.12Å; K455-W458 PolarHBondContact O-N 3.43Å; K455-W458 VanDerWaalsContact O-N 3.13Å; K455-L459 HydrophobicContact CD-CD1 4.22Å; K455-L459 HydrophobicContact CD-CD2 4.19Å; K455-L459 HydrophobicContact CG-CB 4.17Å; K455-L459 HydrophobicContact CG-CD1 3.59Å; K455-L459 HydrophobicContact CG-CD2 4.03Å; K455-L459 HydrophobicContact CG-CG 4.14Å; K455-L459 WeakPolarHBondContact O-CB 3.45Å; K455-L459 PolarHBondContact O-N 3.12Å
456	D	64.7	Low	71.7	Confident	140 Å²	140	75.4 Å²	75.4	75%	0.749	37%	0.374	S	S	*	.	H	α-helix	trans	-61.7	-17.3	-176.5	-57.5	-26	0	0	0	114.2	D454	D454-D456 PolarHBondContact O-N 3.41Å
457	R	62.9	Low	72.3	Confident	112 Å²	112	71.9 Å²	71.9	42%	0.423	36%	0.358	S	S	.	.	H	α-helix	trans	-89.8	-20.1	-178.2	-62.6	174.2	177.8	-100.9	5.6	113.8	H416 D454 K455	H416-R457 PolarHBondContact O-NH1 3.3Å; H416-R457 PolarHBondContact O-NH2 3.34Å; D454-R457 HydrophobicContact CB-CG 4.5Å; D454-R457 WeakPolarHBondContact O-CB 3.33Å; D454-R457 PolarHBondContact O-N 2.99Å; K455-R457 PolarHBondContact O-N 3.21Å
458	W	64	Low	73.2	Confident	56 Å²	56	78.1 Å²	78.1	21%	0.212	39%	0.387	C	S	.	.	H	α-helix	trans	-123.5	-21.7	-179.2	63.1	-96.9	0	0	0	113.9	Y284 T450 L451 Y453 K455 S460	Y284-W458 AromaticContact CD1-CE3 3.95Å; Y284-W458 HydrophobicContact CD1-CE3 3.95Å; Y284-W458 HydrophobicContact CD1-CZ3 4.47Å; Y284-W458 HydrophobicContact CE1-CB 4.34Å; Y284-W458 HydrophobicContact CE1-CD2 4.39Å; Y284-W458 AromaticContact CE1-CE3 3.59Å; Y284-W458 HydrophobicContact CE1-CE3 3.59Å; Y284-W458 HydrophobicContact CE1-CZ3 4.28Å; T450-W458 HydrophobicContact CG2-CB 3.43Å; T450-W458 VanDerWaalsContact CG2-CB 3.43Å; T450-W458 HydrophobicContact CG2-CG 4.07Å; L451-W458 HydrophobicContact CD2-CH2 3.76Å; L451-W458 HydrophobicContact CD2-CZ2 3.75Å; L451-W458 HydrophobicContact CD2-CZ3 4.17Å; Y453-W458 VanDerWaalsContact O-CD1 3.3Å; Y453-W458 PolarHBondContact O-NE1 3.35Å; Y453-W458 VanDerWaalsContact O-NE1 3.12Å; K455-W458 HydrophobicContact CG-CZ2 4.12Å; K455-W458 PolarHBondContact O-N 3.43Å; K455-W458 VanDerWaalsContact O-N 3.13Å; W458-S460 PolarHBondContact O-N 2.97Å
459	L	55.6	Low	74.1	Confident	89 Å²	89	80.8 Å²	80.8	47%	0.466	40%	0.398	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.5	-10.7	-180	-136.1	85.7	0	0	0	113.9	K455 T461	K455-L459 HydrophobicContact CD-CD1 4.22Å; K455-L459 HydrophobicContact CD-CD2 4.19Å; K455-L459 HydrophobicContact CG-CB 4.17Å; K455-L459 HydrophobicContact CG-CD1 3.59Å; K455-L459 HydrophobicContact CG-CD2 4.03Å; K455-L459 HydrophobicContact CG-CG 4.14Å; K455-L459 WeakPolarHBondContact O-CB 3.45Å; K455-L459 PolarHBondContact O-N 3.12Å; L459-T461 PolarHBondContact O-N 3.28Å; L459-T461 VanDerWaalsContact O-N 3.11Å
460	S	51.1	Low	74.5	Confident	76 Å²	76	81.6 Å²	81.6	53%	0.531	41%	0.408	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.8	7	-167.9	59.4	0	0	0	0	115.1	W458	W458-S460 PolarHBondContact O-N 2.97Å
461	T	59.9	Low	75.3	Confident	20 Å²	20	83.3 Å²	83.3	12%	0.123	42%	0.418	C	S	.	.			trans	-127.3	101.2	-166.9	48.7	0	0	0	0	112.4	L459 W463 C485 L486	L459-T461 PolarHBondContact O-N 3.28Å; L459-T461 VanDerWaalsContact O-N 3.11Å; T461-W463 VanDerWaalsContact O-CD1 3.26Å; T461-W463 PolarHBondContact O-N 3.14Å; T461-W463 VanDerWaalsContact O-N 3.15Å; T461-C485 WeakPolarHBondContact CB-SG 3.5Å; T461-C485 WeakPolarHBondContact CG2-SG 3.21Å; T461-L486 HydrophobicContact CG2-CB 4.17Å; T461-L486 HydrophobicContact CG2-CD1 4.13Å; T461-L486 HydrophobicContact CG2-CG 4.27Å
462	Q	76.9	Confident	75.8	Confident	181 Å²	181	83.3 Å²	83.3	85%	0.846	42%	0.422	S	S	*	.			trans	-58.8	114.8	161.9	-177.8	-179.8	2.3	0	0	108.2
463	W	88.2	Confident	76.2	Confident	43 Å²	43	83 Å²	83	16%	0.163	42%	0.423	C	S	.	.			trans	-79.1	132.4	174.6	-71.5	88	0	0	0	110.2	L280 Y283 Y284 T461 L483 K484 C485 F488 L490	L280-W463 HydrophobicContact CD1-CB 3.81Å; L280-W463 HydrophobicContact CD1-CD2 4.34Å; L280-W463 HydrophobicContact CD1-CG 3.8Å; L280-W463 HydrophobicContact CD2-CB 4.39Å; L280-W463 HydrophobicContact CD2-CD2 3.31Å; L280-W463 VanDerWaalsContact CD2-CE2 3.47Å; L280-W463 HydrophobicContact CD2-CE3 3.65Å; L280-W463 HydrophobicContact CD2-CG 3.67Å; L280-W463 HydrophobicContact CD2-CH2 4.12Å; L280-W463 HydrophobicContact CD2-CZ2 3.88Å; L280-W463 HydrophobicContact CD2-CZ3 4.03Å; L280-W463 HydrophobicContact CG-CD2 4.48Å; L280-W463 HydrophobicContact CG-CG 4.41Å; Y283-W463 HydrophobicContact CD1-CH2 4.49Å; Y283-W463 HydrophobicContact CD1-CZ2 4.04Å; Y283-W463 HydrophobicContact CE1-CH2 4.39Å; Y283-W463 AromaticContact CE1-CZ2 3.96Å; Y283-W463 HydrophobicContact CE1-CZ2 3.96Å; Y284-W463 AromaticContact CZ-NE1 3.86Å; Y284-W463 PolarHBondContact OH-NE1 3.22Å; T461-W463 VanDerWaalsContact O-CD1 3.26Å; T461-W463 PolarHBondContact O-N 3.14Å; T461-W463 VanDerWaalsContact O-N 3.15Å; W463-L483 HydrophobicContact CE3-CB 3.63Å; W463-L483 HydrophobicContact CZ3-CB 3.81Å; W463-L483 WeakPolarHBondContact CZ3-O 3.21Å; W463-K484 WeakPolarHBondContact CA-O 3.3Å; W463-C485 HydrophobicContact CD2-CB 4.16Å; W463-C485 HydrophobicContact CE3-CB 3.83Å; W463-C485 HydrophobicContact CH2-CB 3.83Å; W463-C485 HydrophobicContact CZ2-CB 4.1Å; W463-C485 HydrophobicContact CZ3-CB 3.67Å; W463-F488 AromaticContact CH2-CE2 3.64Å; W463-F488 HydrophobicContact CH2-CE2 3.64Å; W463-F488 AromaticContact CH2-CZ 3.97Å; W463-F488 HydrophobicContact CH2-CZ 3.97Å; W463-F488 HydrophobicContact CZ2-CE2 4.35Å; W463-F488 HydrophobicContact CZ2-CZ 4.24Å; W463-F488 HydrophobicContact CZ3-CE2 4.5Å; W463-L490 HydrophobicContact CH2-CD1 3.52Å; W463-L490 HydrophobicContact CH2-CG 3.7Å; W463-L490 HydrophobicContact CZ2-CD1 4.4Å; W463-L490 HydrophobicContact CZ3-CB 4.48Å; W463-L490 HydrophobicContact CZ3-CD1 3.76Å; W463-L490 HydrophobicContact CZ3-CG 3.77Å
464	R	91.1	Very high	76.6	Confident	176 Å²	176	84.3 Å²	84.3	66%	0.664	44%	0.44	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-110.7	118.4	172.9	-173.8	-175.3	-61.2	170.9	2.3	109.6	V466 K484	R464-V466 HydrophobicContact CG-CG2 4.31Å; R464-K484 HydrophobicContact CB-CB 4.43Å; R464-K484 PolarHBondContact N-O 3.05Å; R464-K484 PolarHBondContact O-N 3.36Å
465	L	92.8	Very high	77.4	Confident	50 Å²	50	79.6 Å²	79.6	26%	0.262	42%	0.415	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-75.9	126	170.7	174.6	60.2	0	0	0	109.9	I272 Q273 A276 V471 F481 L483	I272-L465 HydrophobicContact CG2-CD1 4.24Å; I272-L465 HydrophobicContact CG2-CD2 4.3Å; Q273-L465 HydrophobicContact CG-CD2 4.06Å; A276-L465 HydrophobicContact CB-CD1 4.01Å; A276-L465 HydrophobicContact CB-CD2 4.05Å; L465-V471 HydrophobicContact CD2-CB 3.94Å; L465-V471 HydrophobicContact CD2-CG1 3.7Å; L465-V471 HydrophobicContact CG-CG1 3.98Å; L465-F481 HydrophobicContact CD1-CB 4.28Å; L465-F481 HydrophobicContact CD1-CD2 3.53Å; L465-F481 HydrophobicContact CD1-CE2 4.22Å; L465-F481 HydrophobicContact CD1-CG 4.23Å; L465-L483 HydrophobicContact CB-CD2 4.25Å; L465-L483 HydrophobicContact CD1-CD2 3.7Å
466	V	94.4	Very high	78.6	Confident	53 Å²	53	79.2 Å²	79.2	32%	0.321	41%	0.41	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.6	125.8	175	-176.5	0	0	0	0	107.8	R464 V482 K484	R464-V466 HydrophobicContact CG-CG2 4.31Å; V466-V482 HydrophobicContact CB-CB 4.45Å; V466-V482 PolarHBondContact N-O 3.33Å; V466-V482 PolarHBondContact O-N 3.35Å; V466-K484 HydrophobicContact CG2-CD 3.96Å; V466-K484 HydrophobicContact CG2-CG 4.16Å
467	S	92.7	Very high	79.8	Confident	26 Å²	26	77.5 Å²	77.5	18%	0.182	40%	0.401	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-146.6	142.1	-179.1	170.1	0	0	0	0	108	E469	S467-E469 VanDerWaalsContact C-N 3.27Å; S467-E469 WeakPolarHBondContact CB-O 3.38Å; S467-E469 PolarHBondContact OG-N 3.15Å; S467-E469 PolarHBondContact OG-O 3.47Å
468	D	90.4	Very high	81.1	Confident	166 Å²	166	74.6 Å²	74.6	89%	0.888	41%	0.406	S	S	*	.	S	Bend	trans	-72	-27.8	174.3	-64.8	-23.3	0	0	0	111.1
469	E	88.4	Confident	82.5	Confident	60 Å²	60	72.3 Å²	72.3	28%	0.28	40%	0.398	S	S	.	.	S	Bend	trans	-93.7	156.8	174	-57.2	-167.2	167.3	0	0	112.6	I272 S467 V471 R476 I479	I272-E469 HydrophobicContact CD1-CB 4.13Å; S467-E469 VanDerWaalsContact C-N 3.27Å; S467-E469 WeakPolarHBondContact CB-O 3.38Å; S467-E469 PolarHBondContact OG-N 3.15Å; S467-E469 PolarHBondContact OG-O 3.47Å; E469-V471 PolarHBondContact O-N 2.63Å; E469-V471 VanDerWaalsContact O-N 3.17Å; E469-R476 IonicContact OE1-CZ 3.77Å; E469-R476 IonicContact OE1-NE 2.78Å; E469-R476 IonicContact OE1-NH2 3.44Å; E469-R476 PolarHBondContact OE1-NH2 3.16Å; E469-R476 IonicContact OE2-CZ 2.83Å; E469-R476 IonicContact OE2-NE 3.51Å; E469-R476 IonicContact OE2-NH1 3.17Å; E469-R476 IonicContact OE2-NH2 3.49Å; E469-R476 PolarHBondContact OE2-NH2 3.02Å; E469-I479 WeakPolarHBondContact OE2-CD1 3.31Å
470	A	85.8	Confident	84.3	Confident	54 Å²	54	71.1 Å²	71.1	45%	0.446	39%	0.394	S	S	.	.			trans	-54.1	122.3	172.8	0	0	0	0	0	110.8	T472 N473	A470-T472 PolarHBondContact O-N 3.1Å; A470-T472 VanDerWaalsContact O-N 3.08Å; A470-N473 WeakPolarHBondContact O-CB 3.47Å; A470-N473 PolarHBondContact O-N 3.14Å
471	V	83.4	Confident	86.5	Confident	43 Å²	43	67.6 Å²	67.6	26%	0.261	37%	0.369	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.7	-18	-172	-66.5	0	0	0	0	113.6	I272 Q273 L465 E469 N473	I272-V471 PolarHBondContact N-O 3.27Å; Q273-V471 HydrophobicContact CG-CB 3.72Å; Q273-V471 HydrophobicContact CG-CG2 3.86Å; Q273-V471 WeakPolarHBondContact CG-O 3.38Å; Q273-V471 PolarHBondContact N-O 2.88Å; Q273-V471 VanDerWaalsContact N-O 3.08Å; L465-V471 HydrophobicContact CD2-CB 3.94Å; L465-V471 HydrophobicContact CD2-CG1 3.7Å; L465-V471 HydrophobicContact CG-CG1 3.98Å; E469-V471 PolarHBondContact O-N 2.63Å; E469-V471 VanDerWaalsContact O-N 3.17Å; V471-N473 VanDerWaalsContact C-N 3.32Å
472	T	80.3	Confident	88.2	Confident	95 Å²	95	68.1 Å²	68.1	58%	0.583	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.2	-17.7	173.2	49.6	0	0	0	0	113.2	A470	A470-T472 PolarHBondContact O-N 3.1Å; A470-T472 VanDerWaalsContact O-N 3.08Å
473	N	77.5	Confident	89	Confident	58 Å²	58	59.6 Å²	59.6	31%	0.31	33%	0.332	S	S	.	.	S	Bend	trans	-65.4	151.8	178.2	-70.4	-15.2	0	0	0	111.6	S271 I272 A470 V471	S271-N473 CarbonylContact C-O 3.56Å; S271-N473 WeakPolarHBondContact CA-O 3.29Å; S271-N473 WeakPolarHBondContact CB-O 3.44Å; I272-N473 PolarHBondContact N-O 3.05Å; A470-N473 WeakPolarHBondContact O-CB 3.47Å; A470-N473 PolarHBondContact O-N 3.14Å; V471-N473 VanDerWaalsContact C-N 3.32Å
474	G	79.4	Confident	89.1	Confident	40 Å²	40	62.5 Å²	62.5	41%	0.412	35%	0.346	S	S	.	.	B	Isolated β-bridge	trans	-65	150	169.8	0	0	0	0	0	112.3	L270	L270-G474 CarbonylContact O-C 3.53Å; L270-G474 WeakPolarHBondContact O-CA 3.37Å
475	L	83.8	Confident	88.9	Confident	8 Å²	8	54.9 Å²	54.9	4%	0.042	32%	0.32	C	S	.	.	P	Polyproline II helix	trans	-55.8	137.3	170	-70.8	175.9	0	0	0	110.7	F250 L267 L270 I272 A275 F481 V494	F250-L475 HydrophobicContact CD2-CB 3.76Å; F250-L475 HydrophobicContact CD2-CD1 4.02Å; F250-L475 HydrophobicContact CE2-CB 3.66Å; F250-L475 WeakPolarHBondContact CE2-O 3.46Å; F250-L475 HydrophobicContact CG-CB 4.36Å; F250-L475 HydrophobicContact CZ-CB 4.16Å; F250-L475 WeakPolarHBondContact CZ-O 3.14Å; L267-L475 HydrophobicContact CD1-CD1 4.47Å; L270-L475 HydrophobicContact CB-CD1 4.49Å; L270-L475 WeakPolarHBondContact O-CG 3.26Å; L270-L475 PolarHBondContact O-N 2.97Å; I272-L475 HydrophobicContact CG1-CD2 4.28Å; A275-L475 HydrophobicContact CB-CD1 3.77Å; A275-L475 HydrophobicContact CB-CD2 3.96Å; A275-L475 HydrophobicContact CB-CG 4.09Å; L475-F481 HydrophobicContact CD2-CE1 4.15Å; L475-V494 HydrophobicContact CB-CG1 4.43Å; L475-V494 HydrophobicContact CD2-CG1 4.31Å; L475-V494 HydrophobicContact CD2-CG2 3.85Å
476	R	87.3	Confident	88.3	Confident	117 Å²	117	59.1 Å²	59.1	44%	0.442	34%	0.342	S	S	.	.			trans	-129.7	163	173.2	-59	-170.3	-77.8	-103.4	9.5	109.7	E469 I479 V494	E469-R476 IonicContact OE1-CZ 3.77Å; E469-R476 IonicContact OE1-NE 2.78Å; E469-R476 IonicContact OE1-NH2 3.44Å; E469-R476 PolarHBondContact OE1-NH2 3.16Å; E469-R476 IonicContact OE2-CZ 2.83Å; E469-R476 IonicContact OE2-NE 3.51Å; E469-R476 IonicContact OE2-NH1 3.17Å; E469-R476 IonicContact OE2-NH2 3.49Å; E469-R476 PolarHBondContact OE2-NH2 3.02Å; R476-I479 HydrophobicContact CB-CD1 3.68Å; R476-I479 HydrophobicContact CB-CG1 3.96Å; R476-I479 HydrophobicContact CG-CD1 4.14Å; R476-I479 VanDerWaalsContact N-CD1 3.31Å; R476-I479 PolarHBondContact O-N 3.03Å; R476-V494 VanDerWaalsContact O-CG1 3.31Å; R476-V494 WeakPolarHBondContact O-CG1 3.23Å
477	D	89.9	Confident	87.7	Confident	104 Å²	104	61.9 Å²	61.9	56%	0.556	36%	0.355	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.6	136.7	175.1	-170.3	47.2	0	0	0	110.9	I479 K495 K496	D477-I479 VanDerWaalsContact C-N 3.26Å; D477-I479 PolarHBondContact O-N 2.85Å; D477-K495 WeakPolarHBondContact OD1-CA 3.27Å; D477-K496 HydrophobicContact CB-CB 3.87Å; D477-K496 WeakPolarHBondContact OD1-CB 3.32Å; D477-K496 PolarHBondContact OD1-N 3.46Å
478	G	90.1	Very high	87.4	Confident	51 Å²	51	61.7 Å²	61.7	53%	0.526	35%	0.351	S	S	.	.	T	Hydrogen-bonded Turn	trans	78	0.6	177.6	0	0	0	0	0	115.5	V480 V494	G478-V480 PolarHBondContact O-N 2.97Å; G478-V494 WeakPolarHBondContact CA-O 3.49Å; G478-V494 PolarHBondContact N-O 2.94Å
479	I	93	Very high	87.5	Confident	9 Å²	9	54.9 Å²	54.9	5%	0.046	32%	0.316	C	S	.	.			trans	-64.2	138	174	-67.7	-175.9	0	0	0	109.5	I272 E469 R476 D477 F481 V494	I272-I479 HydrophobicContact CD1-CD1 4.23Å; I272-I479 HydrophobicContact CD1-CG2 4.32Å; E469-I479 WeakPolarHBondContact OE2-CD1 3.31Å; R476-I479 HydrophobicContact CB-CD1 3.68Å; R476-I479 HydrophobicContact CB-CG1 3.96Å; R476-I479 HydrophobicContact CG-CD1 4.14Å; R476-I479 VanDerWaalsContact N-CD1 3.31Å; R476-I479 PolarHBondContact O-N 3.03Å; D477-I479 VanDerWaalsContact C-N 3.26Å; D477-I479 PolarHBondContact O-N 2.85Å; I479-F481 HydrophobicContact CG2-CD1 4.33Å; I479-V494 HydrophobicContact CB-CB 4.22Å; I479-V494 HydrophobicContact CB-CG2 3.97Å; I479-V494 HydrophobicContact CG2-CG2 4.19Å; I479-V494 WeakPolarHBondContact O-CB 3.36Å; I479-V494 VanDerWaalsContact O-CG2 3.22Å; I479-V494 WeakPolarHBondContact O-CG2 3.49Å; I479-V494 PolarHBondContact O-N 3.12Å
480	V	94.9	Very high	87.7	Confident	64 Å²	64	52 Å²	52	39%	0.388	30%	0.303	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.3	129.2	168.3	-177.7	0	0	0	0	108.4	G478 V491 V492	G478-V480 PolarHBondContact O-N 2.97Å; V480-V491 HydrophobicContact CG1-CG1 3.93Å; V480-V492 VanDerWaalsContact CA-O 3.3Å; V480-V492 WeakPolarHBondContact CA-O 3.38Å
481	F	95.8	Very high	88.2	Confident	1 Å²	1	51.9 Å²	51.9	0%	0.004	30%	0.296	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.8	157	171.7	67.6	-91.3	0	0	0	110.4	L252 I272 A275 A276 L465 L475 I479 L483 V492 V494	L252-F481 HydrophobicContact CD2-CE1 4.49Å; I272-F481 HydrophobicContact CG2-CB 4.07Å; I272-F481 HydrophobicContact CG2-CD1 3.87Å; I272-F481 HydrophobicContact CG2-CD2 4.26Å; I272-F481 HydrophobicContact CG2-CE1 4.34Å; I272-F481 HydrophobicContact CG2-CG 3.81Å; A275-F481 HydrophobicContact CB-CZ 4.32Å; A276-F481 HydrophobicContact CB-CE2 4.04Å; L465-F481 HydrophobicContact CD1-CB 4.28Å; L465-F481 HydrophobicContact CD1-CD2 3.53Å; L465-F481 HydrophobicContact CD1-CE2 4.22Å; L465-F481 HydrophobicContact CD1-CG 4.23Å; L475-F481 HydrophobicContact CD2-CE1 4.15Å; I479-F481 HydrophobicContact CG2-CD1 4.33Å; F481-L483 HydrophobicContact CD2-CD2 4.39Å; F481-L483 HydrophobicContact CD2-CG 4.45Å; F481-L483 HydrophobicContact CE2-CD1 4.45Å; F481-L483 HydrophobicContact CE2-CD2 4.28Å; F481-L483 HydrophobicContact CE2-CG 4.28Å; F481-V492 HydrophobicContact CD1-CB 4.12Å; F481-V492 HydrophobicContact CD1-CG1 4.31Å; F481-V492 HydrophobicContact CD2-CB 4.07Å; F481-V492 HydrophobicContact CD2-CG2 4.12Å; F481-V492 HydrophobicContact CE1-CB 3.83Å; F481-V492 HydrophobicContact CE1-CG1 3.59Å; F481-V492 HydrophobicContact CE2-CB 3.77Å; F481-V492 HydrophobicContact CE2-CG1 4.14Å; F481-V492 HydrophobicContact CE2-CG2 3.63Å; F481-V492 HydrophobicContact CG-CB 4.25Å; F481-V492 HydrophobicContact CZ-CB 3.65Å; F481-V492 HydrophobicContact CZ-CG1 3.51Å; F481-V492 HydrophobicContact CZ-CG2 3.89Å; F481-V492 PolarHBondContact N-O 3.48Å; F481-V492 PolarHBondContact O-N 2.91Å; F481-V494 HydrophobicContact CD1-CG2 4.23Å; F481-V494 HydrophobicContact CE1-CG2 4Å
482	V	95.9	Very high	88.8	Confident	31 Å²	31	49.9 Å²	49.9	19%	0.188	28%	0.284	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.5	130.4	-172.6	-175.9	0	0	0	0	110	V466 K484 L490 V491	V466-V482 HydrophobicContact CB-CB 4.45Å; V466-V482 PolarHBondContact N-O 3.33Å; V466-V482 PolarHBondContact O-N 3.35Å; V482-K484 HydrophobicContact CG1-CG 3.89Å; V482-L490 CarbonylContact C-O 3.58Å; V482-L490 WeakPolarHBondContact CA-O 3.45Å; V482-V491 HydrophobicContact CG2-CG2 4.37Å
483	L	93.7	Very high	89.6	Confident	2 Å²	2	47.7 Å²	47.7	1%	0.01	27%	0.269	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.9	109.2	169.9	-55	169.5	0	0	0	107.1	A276 V279 L280 W463 L465 F481 S489 L490 V492	A276-L483 HydrophobicContact CB-CD2 3.59Å; V279-L483 HydrophobicContact CB-CD1 4.03Å; V279-L483 HydrophobicContact CG1-CD1 3.59Å; L280-L483 HydrophobicContact CD2-CB 4.48Å; L280-L483 HydrophobicContact CD2-CD1 3.84Å; L280-L483 HydrophobicContact CG-CD1 3.99Å; W463-L483 HydrophobicContact CE3-CB 3.63Å; W463-L483 HydrophobicContact CZ3-CB 3.81Å; W463-L483 WeakPolarHBondContact CZ3-O 3.21Å; L465-L483 HydrophobicContact CB-CD2 4.25Å; L465-L483 HydrophobicContact CD1-CD2 3.7Å; F481-L483 HydrophobicContact CD2-CD2 4.39Å; F481-L483 HydrophobicContact CD2-CG 4.45Å; F481-L483 HydrophobicContact CE2-CD1 4.45Å; F481-L483 HydrophobicContact CE2-CD2 4.28Å; F481-L483 HydrophobicContact CE2-CG 4.28Å; L483-S489 CarbonylContact O-C 3.43Å; L483-S489 VanDerWaalsContact O-CA 3.22Å; L483-S489 WeakPolarHBondContact O-CA 3.37Å; L483-S489 WeakPolarHBondContact O-CB 3.28Å; L483-L490 HydrophobicContact CB-CB 4.19Å; L483-L490 HydrophobicContact CD1-CD1 4.36Å; L483-L490 PolarHBondContact N-O 3.34Å; L483-L490 PolarHBondContact O-N 3.21Å; L483-V492 HydrophobicContact CD1-CG2 4.39Å
484	K	91	Very high	90.4	Very high	104 Å²	104	45 Å²	45	45%	0.452	25%	0.254	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.9	130.7	-179.9	-67.1	-169.4	178.6	-179.1	0	110.5	W463 R464 V466 V482	W463-K484 WeakPolarHBondContact CA-O 3.3Å; R464-K484 HydrophobicContact CB-CB 4.43Å; R464-K484 PolarHBondContact N-O 3.05Å; R464-K484 PolarHBondContact O-N 3.36Å; V466-K484 HydrophobicContact CG2-CD 3.96Å; V466-K484 HydrophobicContact CG2-CG 4.16Å; V482-K484 HydrophobicContact CG1-CG 3.89Å
485	C	86	Confident	91	Very high	17 Å²	17	49.1 Å²	49.1	12%	0.115	26%	0.261	C	S	.	.			trans	-114.2	170.1	169.9	165.5	0	0	0	0	107.5	T461 W463 D487 F488	T461-C485 WeakPolarHBondContact CB-SG 3.5Å; T461-C485 WeakPolarHBondContact CG2-SG 3.21Å; W463-C485 HydrophobicContact CD2-CB 4.16Å; W463-C485 HydrophobicContact CE3-CB 3.83Å; W463-C485 HydrophobicContact CH2-CB 3.83Å; W463-C485 HydrophobicContact CZ2-CB 4.1Å; W463-C485 HydrophobicContact CZ3-CB 3.67Å; C485-D487 VanDerWaalsContact C-N 3.33Å; C485-D487 PolarHBondContact O-N 3.47Å; C485-F488 CarbonylContact C-O 3.58Å; C485-F488 WeakPolarHBondContact CA-O 3.37Å; C485-F488 HydrophobicContact CB-CZ 4.49Å; C485-F488 VanDerWaalsContact CB-O 3.28Å; C485-F488 WeakPolarHBondContact CB-O 3.32Å; C485-F488 PolarHBondContact N-O 2.98Å; C485-F488 VanDerWaalsContact O-O 3.08Å
486	L	81.3	Confident	91.3	Very high	139 Å²	139	54.9 Å²	54.9	73%	0.728	29%	0.286	S	S	*	.	S	Bend	trans	-60.1	-42.4	-177.3	-71.5	169.5	0	0	0	112.3	T461	T461-L486 HydrophobicContact CG2-CB 4.17Å; T461-L486 HydrophobicContact CG2-CD1 4.13Å; T461-L486 HydrophobicContact CG2-CG 4.27Å
487	D	80.8	Confident	91.3	Very high	111 Å²	111	51.7 Å²	51.7	59%	0.594	28%	0.277	S	S	*	.	S	Bend	trans	-100.8	-20.6	-171	-62.5	-36.2	0	0	0	114	Y290 C485	Y290-D487 HydrophobicContact CD1-CB 4.49Å; Y290-D487 HydrophobicContact CE1-CB 3.88Å; C485-D487 VanDerWaalsContact C-N 3.33Å; C485-D487 PolarHBondContact O-N 3.47Å
488	F	87.4	Confident	90.9	Very high	22 Å²	22	51.6 Å²	51.6	10%	0.096	28%	0.282	C	S	.	.			trans	-157.6	177.1	-176.3	64.8	-86.2	0	0	0	111.3	R256 T258 Y283 Y290 W463 C485 L490	R256-F488 HydrophobicContact CG-CD2 3.71Å; R256-F488 HydrophobicContact CG-CE2 4.22Å; R256-F488 HydrophobicContact CG-CG 4.36Å; T258-F488 HydrophobicContact CG2-CB 3.5Å; Y283-F488 HydrophobicContact CE1-CZ 4.24Å; Y283-F488 HydrophobicContact CE2-CE2 4.2Å; Y283-F488 AromaticContact CZ-CE2 3.84Å; Y283-F488 AromaticContact CZ-CZ 3.73Å; Y283-F488 WeakPolarHBondContact OH-CE2 3.17Å; Y283-F488 WeakPolarHBondContact OH-CZ 3.42Å; Y290-F488 AromaticContact CD1-CD1 3.65Å; Y290-F488 HydrophobicContact CD1-CD1 3.65Å; Y290-F488 AromaticContact CD1-CE1 3.94Å; Y290-F488 HydrophobicContact CD1-CE1 3.94Å; Y290-F488 HydrophobicContact CD2-CD1 4.43Å; Y290-F488 HydrophobicContact CE1-CD1 4.02Å; Y290-F488 AromaticContact CG-CD1 3.86Å; Y290-F488 HydrophobicContact CG-CD1 3.86Å; Y290-F488 HydrophobicContact CG-CE1 4.05Å; W463-F488 AromaticContact CH2-CE2 3.64Å; W463-F488 HydrophobicContact CH2-CE2 3.64Å; W463-F488 AromaticContact CH2-CZ 3.97Å; W463-F488 HydrophobicContact CH2-CZ 3.97Å; W463-F488 HydrophobicContact CZ2-CE2 4.35Å; W463-F488 HydrophobicContact CZ2-CZ 4.24Å; W463-F488 HydrophobicContact CZ3-CE2 4.5Å; C485-F488 CarbonylContact C-O 3.58Å; C485-F488 WeakPolarHBondContact CA-O 3.37Å; C485-F488 HydrophobicContact CB-CZ 4.49Å; C485-F488 VanDerWaalsContact CB-O 3.28Å; C485-F488 WeakPolarHBondContact CB-O 3.32Å; C485-F488 PolarHBondContact N-O 2.98Å; C485-F488 VanDerWaalsContact O-O 3.08Å; F488-L490 HydrophobicContact CD2-CD2 4.45Å; F488-L490 HydrophobicContact CE2-CD2 4.13Å; F488-L490 HydrophobicContact CE2-CG 4.44Å
489	S	91.9	Very high	90.2	Very high	23 Å²	23	54 Å²	54	16%	0.161	28%	0.278	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-134	152.6	174.2	57.4	0	0	0	0	111.7	S257 L483	S257-S489 WeakPolarHBondContact CB-O 3.37Å; S257-S489 VanDerWaalsContact CB-OG 3.3Å; S257-S489 WeakPolarHBondContact CB-OG 3.27Å; S257-S489 PolarHBondContact N-O 3.3Å; S257-S489 PolarHBondContact OG-N 2.83Å; S257-S489 PolarHBondContact OG-O 2.84Å; S257-S489 VanDerWaalsContact OG-O 3.05Å; S257-S489 PolarHBondContact OG-OG 3.16Å; L483-S489 CarbonylContact O-C 3.43Å; L483-S489 VanDerWaalsContact O-CA 3.22Å; L483-S489 WeakPolarHBondContact O-CA 3.37Å; L483-S489 WeakPolarHBondContact O-CB 3.28Å
490	L	93.4	Very high	89.3	Confident	0 Å²	0	58.7 Å²	58.7	0%	0	30%	0.302	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-101.3	118.4	167.3	-55.3	173.5	0	0	0	107.9	V254 V255 R256 L280 Y283 W463 V482 L483 F488	V254-L490 HydrophobicContact CG1-CB 4.05Å; V254-L490 HydrophobicContact CG1-CD1 4.42Å; V254-L490 HydrophobicContact CG1-CD2 4.42Å; V255-L490 WeakPolarHBondContact O-CA 3.35Å; R256-L490 HydrophobicContact CB-CD2 3.95Å; R256-L490 HydrophobicContact CG-CD2 4.27Å; L280-L490 HydrophobicContact CD2-CD1 4.34Å; Y283-L490 HydrophobicContact CD1-CD1 4.46Å; Y283-L490 HydrophobicContact CD2-CD1 3.61Å; Y283-L490 HydrophobicContact CD2-CD2 3.77Å; Y283-L490 HydrophobicContact CD2-CG 4.3Å; Y283-L490 HydrophobicContact CE2-CD1 4.25Å; Y283-L490 HydrophobicContact CE2-CD2 3.77Å; Y283-L490 HydrophobicContact CG-CD1 3.75Å; W463-L490 HydrophobicContact CH2-CD1 3.52Å; W463-L490 HydrophobicContact CH2-CG 3.7Å; W463-L490 HydrophobicContact CZ2-CD1 4.4Å; W463-L490 HydrophobicContact CZ3-CB 4.48Å; W463-L490 HydrophobicContact CZ3-CD1 3.76Å; W463-L490 HydrophobicContact CZ3-CG 3.77Å; V482-L490 CarbonylContact C-O 3.58Å; V482-L490 WeakPolarHBondContact CA-O 3.45Å; L483-L490 HydrophobicContact CB-CB 4.19Å; L483-L490 HydrophobicContact CD1-CD1 4.36Å; L483-L490 PolarHBondContact N-O 3.34Å; L483-L490 PolarHBondContact O-N 3.21Å; F488-L490 HydrophobicContact CD2-CD2 4.45Å; F488-L490 HydrophobicContact CE2-CD2 4.13Å; F488-L490 HydrophobicContact CE2-CG 4.44Å
491	V	95.8	Very high	88.1	Confident	51 Å²	51	62.1 Å²	62.1	31%	0.309	32%	0.317	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.8	122.2	173.7	-176.9	0	0	0	0	107.4	V254 V255 V480 V482	V254-V491 WeakPolarHBondContact CA-O 3.35Å; V255-V491 PolarHBondContact N-O 3.2Å; V255-V491 PolarHBondContact O-N 2.9Å; V480-V491 HydrophobicContact CG1-CG1 3.93Å; V482-V491 HydrophobicContact CG2-CG2 4.37Å
492	V	96.2	Very high	86.9	Confident	0 Å²	0	66.2 Å²	66.2	0%	0	34%	0.338	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-111.4	118.1	-177.7	-172.3	0	0	0	0	109	L252 Q253 V254 V279 V480 F481 L483	L252-V492 HydrophobicContact CB-CG1 4.04Å; L252-V492 HydrophobicContact CD1-CG1 4.31Å; L252-V492 HydrophobicContact CD2-CG1 3.75Å; L252-V492 HydrophobicContact CG-CG1 4.28Å; Q253-V492 WeakPolarHBondContact O-CA 3.41Å; V254-V492 HydrophobicContact CG1-CG2 4.31Å; V254-V492 HydrophobicContact CG2-CG1 4.09Å; V254-V492 HydrophobicContact CG2-CG2 4.1Å; V279-V492 HydrophobicContact CG1-CG2 4.08Å; V279-V492 HydrophobicContact CG2-CG1 4.46Å; V279-V492 HydrophobicContact CG2-CG2 4.47Å; V480-V492 VanDerWaalsContact CA-O 3.3Å; V480-V492 WeakPolarHBondContact CA-O 3.38Å; F481-V492 HydrophobicContact CD1-CB 4.12Å; F481-V492 HydrophobicContact CD1-CG1 4.31Å; F481-V492 HydrophobicContact CD2-CB 4.07Å; F481-V492 HydrophobicContact CD2-CG2 4.12Å; F481-V492 HydrophobicContact CE1-CB 3.83Å; F481-V492 HydrophobicContact CE1-CG1 3.59Å; F481-V492 HydrophobicContact CE2-CB 3.77Å; F481-V492 HydrophobicContact CE2-CG1 4.14Å; F481-V492 HydrophobicContact CE2-CG2 3.63Å; F481-V492 HydrophobicContact CG-CB 4.25Å; F481-V492 HydrophobicContact CZ-CB 3.65Å; F481-V492 HydrophobicContact CZ-CG1 3.51Å; F481-V492 HydrophobicContact CZ-CG2 3.89Å; F481-V492 PolarHBondContact N-O 3.48Å; F481-V492 PolarHBondContact O-N 2.91Å; L483-V492 HydrophobicContact CD1-CG2 4.39Å
493	N	96	Very high	85.8	Confident	50 Å²	50	70 Å²	70	27%	0.267	37%	0.366	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.3	122.8	175.3	-172.5	-22.3	0	0	0	109.7	L252 Q253	L252-N493 CarbonylContact C-O 3.56Å; L252-N493 WeakPolarHBondContact CA-O 3.37Å; Q253-N493 HydrophobicContact CB-CB 4.36Å; Q253-N493 PolarHBondContact N-O 2.72Å; Q253-N493 PolarHBondContact O-N 2.75Å
494	V	94.7	Very high	84.8	Confident	0 Å²	0	74.4 Å²	74.4	0%	0	39%	0.387	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.9	120.7	-177	-170.1	0	0	0	0	109.5	F250 L252 L475 R476 G478 I479 F481	F250-V494 HydrophobicContact CB-CG1 3.94Å; F250-V494 HydrophobicContact CD1-CG1 3.83Å; F250-V494 HydrophobicContact CG-CG1 3.97Å; L252-V494 HydrophobicContact CD2-CB 4.02Å; L252-V494 HydrophobicContact CD2-CG1 3.97Å; L252-V494 HydrophobicContact CD2-CG2 3.51Å; L475-V494 HydrophobicContact CB-CG1 4.43Å; L475-V494 HydrophobicContact CD2-CG1 4.31Å; L475-V494 HydrophobicContact CD2-CG2 3.85Å; R476-V494 VanDerWaalsContact O-CG1 3.31Å; R476-V494 WeakPolarHBondContact O-CG1 3.23Å; G478-V494 WeakPolarHBondContact CA-O 3.49Å; G478-V494 PolarHBondContact N-O 2.94Å; I479-V494 HydrophobicContact CB-CB 4.22Å; I479-V494 HydrophobicContact CB-CG2 3.97Å; I479-V494 HydrophobicContact CG2-CG2 4.19Å; I479-V494 WeakPolarHBondContact O-CB 3.36Å; I479-V494 VanDerWaalsContact O-CG2 3.22Å; I479-V494 WeakPolarHBondContact O-CG2 3.49Å; I479-V494 PolarHBondContact O-N 3.12Å; F481-V494 HydrophobicContact CD1-CG2 4.23Å; F481-V494 HydrophobicContact CE1-CG2 4Å
495	K	93.1	Very high	84.3	Confident	127 Å²	127	77.9 Å²	77.9	55%	0.552	40%	0.404	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-119.9	137.7	170.6	-68	-160.9	175.6	-172.5	0	111.3	F250 T251 D477	F250-K495 CarbonylContact C-O 3.47Å; F250-K495 VanDerWaalsContact CA-O 3.22Å; F250-K495 WeakPolarHBondContact CA-O 3.44Å; T251-K495 PolarHBondContact N-O 3.36Å; T251-K495 PolarHBondContact O-N 2.99Å; D477-K495 WeakPolarHBondContact OD1-CA 3.27Å
496	K	89.6	Confident	83.9	Confident	130 Å²	130	84.3 Å²	84.3	57%	0.565	43%	0.431	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-75.7	133.4	173.7	-172.9	179.3	177.4	-174.1	0	110.1	F250 D477	F250-K496 HydrophobicContact CD1-CB 4.16Å; F250-K496 HydrophobicContact CE1-CB 4.21Å; F250-K496 HydrophobicContact CE1-CG 4.33Å; D477-K496 HydrophobicContact CB-CB 3.87Å; D477-K496 WeakPolarHBondContact OD1-CB 3.32Å; D477-K496 PolarHBondContact OD1-N 3.46Å
497	I	86	Confident	83.6	Confident	50 Å²	50	82.4 Å²	82.4	26%	0.256	42%	0.42	S	S	.	.	P	Polyproline II helix	trans	-66.2	129.8	174.4	-63.7	170.3	0	0	0	108	P248 V249 T251	P248-I497 HydrophobicContact CB-CD1 3.83Å; P248-I497 HydrophobicContact CG-CD1 4.25Å; V249-I497 WeakPolarHBondContact O-CB 3.35Å; V249-I497 PolarHBondContact O-N 3.4Å; T251-I497 WeakPolarHBondContact OG1-CG1 3.38Å
498	P	83.4	Confident	83.2	Confident	101 Å²	101	79.9 Å²	79.9	66%	0.656	41%	0.407	S	S	*	.	P	Polyproline II helix	trans	-65.1	156.7	-179.3	27.3	-34.8	0	0	0	111.6	I500	P498-I500 PolarHBondContact O-N 3.07Å
499	F	73.5	Confident	82.5	Confident	103 Å²	103	83.2 Å²	83.2	45%	0.452	43%	0.43	S	S	.	.	P	Polyproline II helix	trans	-70.5	119.3	170.5	-176.8	-101.6	0	0	0	108.7	R175 R176 D178 I501	R175-F499 WeakPolarHBondContact O-CE2 3.27Å; R176-F499 WeakPolarHBondContact O-CD2 3.45Å; R176-F499 VanDerWaalsContact O-CE2 3.24Å; R176-F499 WeakPolarHBondContact O-CE2 3.46Å; D178-F499 HydrophobicContact CB-CZ 4.37Å; F499-I501 HydrophobicContact CD1-CD1 4.16Å; F499-I501 HydrophobicContact CD1-CG1 3.68Å; F499-I501 HydrophobicContact CE1-CD1 3.95Å; F499-I501 HydrophobicContact CE1-CG1 3.41Å; F499-I501 VanDerWaalsContact CE1-CG1 3.41Å
500	I	74.3	Confident	81.3	Confident	107 Å²	107	86.5 Å²	86.5	55%	0.549	44%	0.442	S	S	.	.	P	Polyproline II helix	trans	-97.8	122.2	-178.1	-57.7	172.6	0	0	0	108.1	P498	P498-I500 PolarHBondContact O-N 3.07Å
501	I	71	Confident	80.1	Confident	136 Å²	136	90 Å²	90	70%	0.697	47%	0.467	S	S	*	.	P	Polyproline II helix	trans	-101.9	119.6	170.2	-60.2	172.2	0	0	0	106.7	F499	F499-I501 HydrophobicContact CD1-CD1 4.16Å; F499-I501 HydrophobicContact CD1-CG1 3.68Å; F499-I501 HydrophobicContact CE1-CD1 3.95Å; F499-I501 HydrophobicContact CE1-CG1 3.41Å; F499-I501 VanDerWaalsContact CE1-CG1 3.41Å
502	L	70.7	Confident	78.6	Confident	86 Å²	86	93.2 Å²	93.2	45%	0.45	48%	0.478	S	S	.	.			trans	-108	120.1	176.3	-176	69.5	0	0	0	109	M179	M179-L502 HydrophobicContact CE-CB 4.19Å; M179-L502 HydrophobicContact CE-CD2 3.78Å
503	S	72.4	Confident	77.2	Confident	111 Å²	111	100.3 Å²	100.3	78%	0.776	51%	0.509	S	S	*	.			trans	-93.5	129.4	166.9	53.2	0	0	0	0	109.4
504	E	73.2	Confident	75.8	Confident	95 Å²	95	106.9 Å²	106.9	44%	0.444	54%	0.535	S	S	.	.			trans	-97.9	125.4	172.2	-69.6	178.6	-158.8	0	0	108.5	P180 R181	P180-E504 HydrophobicContact CG-CG 4.21Å; R181-E504 IonicContact CZ-OE2 2.65Å; R181-E504 IonicContact NE-OE1 3.06Å; R181-E504 IonicContact NE-OE2 3.01Å; R181-E504 PolarHBondContact NE-OE2 3.03Å; R181-E504 VanDerWaalsContact NE-OE2 3.08Å; R181-E504 IonicContact NH2-OE2 2.74Å; R181-E504 PolarHBondContact NH2-OE2 3.37Å
505	E	79.2	Confident	74.5	Confident	176 Å²	176	112.9 Å²	112.9	82%	0.822	57%	0.572	S	S	*	*			trans	-114.6	120.4	168.9	-174.1	176.2	-179.3	0	0	108.3
506	F	77.4	Confident	72.8	Confident	153 Å²	153	113.8 Å²	113.8	67%	0.671	58%	0.582	S	S	*	*			trans	-86.8	112.1	174.4	179.1	-99.8	0	0	0	109.4	D508	F506-D508 HydrophobicContact CE1-CB 4.44Å
507	I	75.1	Confident	71.2	Confident	98 Å²	98	118.3 Å²	118.3	50%	0.503	60%	0.595	S	S	.	*			trans	-85.7	114.4	173	-58.3	173.2	0	0	0	107.7	S511 H512	I507-S511 VanDerWaalsContact CG2-OG 3.31Å; I507-S511 WeakPolarHBondContact CG2-OG 3.1Å; I507-H512 WeakPolarHBondContact CG2-NE2 3.49Å
508	D	73.4	Confident	69.9	Low	59 Å²	59	122.8 Å²	122.8	32%	0.316	62%	0.619	S	S	.	*			trans	-61.1	127.5	178	-176.9	-11.4	0	0	0	109.4	F506 K510 S511	F506-D508 HydrophobicContact CE1-CB 4.44Å; D508-K510 PolarHBondContact O-N 2.84Å; D508-K510 WeakPolarHBondContact OD1-CB 3.39Å; D508-K510 PolarHBondContact OD1-N 2.98Å; D508-S511 VanDerWaalsContact O-CB 3.26Å; D508-S511 WeakPolarHBondContact O-CB 3.4Å; D508-S511 PolarHBondContact O-N 3.42Å; D508-S511 PolarHBondContact O-OG 2.9Å
509	P	72.3	Confident	68.5	Low	91 Å²	91	126 Å²	126	59%	0.591	63%	0.626	S	S	*	*	G	3₁₀ helix	trans	-56.7	-20.5	173.4	21.7	-32.9	0	0	0	113.5	S511	P509-S511 VanDerWaalsContact C-N 3.35Å
510	K	67.8	Low	67.9	Low	92 Å²	92	126.3 Å²	126.3	40%	0.4	64%	0.64	S	S	.	*	G	3₁₀ helix	trans	-74.7	-20	171.8	-62.8	178.6	-175.1	172.3	0	113.5	D508 H512 K513	D508-K510 PolarHBondContact O-N 2.84Å; D508-K510 WeakPolarHBondContact OD1-CB 3.39Å; D508-K510 PolarHBondContact OD1-N 2.98Å; K510-H512 PolarHBondContact O-N 3.19Å; K510-K513 HydrophobicContact CB-CD 4.42Å; K510-K513 HydrophobicContact CG-CD 4.34Å; K510-K513 WeakPolarHBondContact O-CB 3.48Å; K510-K513 PolarHBondContact O-N 3.3Å; K510-K513 VanDerWaalsContact O-N 3.09Å
511	S	66.6	Low	67.1	Low	75 Å²	75	129.1 Å²	129.1	52%	0.524	65%	0.651	S	S	.	*	G	3₁₀ helix	trans	-68.8	-18.3	176.3	71.7	0	0	0	0	113.3	I507 D508 P509	I507-S511 VanDerWaalsContact CG2-OG 3.31Å; I507-S511 WeakPolarHBondContact CG2-OG 3.1Å; D508-S511 VanDerWaalsContact O-CB 3.26Å; D508-S511 WeakPolarHBondContact O-CB 3.4Å; D508-S511 PolarHBondContact O-N 3.42Å; D508-S511 PolarHBondContact O-OG 2.9Å; P509-S511 VanDerWaalsContact C-N 3.35Å
512	H	64.4	Low	66	Low	118 Å²	118	128.9 Å²	128.9	55%	0.546	66%	0.656	S	S	.	*	G	3₁₀ helix	trans	-94.8	6.9	172.6	-57.6	-54	0	0	0	113.5	I507 K510 F514	I507-H512 WeakPolarHBondContact CG2-NE2 3.49Å; K510-H512 PolarHBondContact O-N 3.19Å; H512-F514 WeakPolarHBondContact O-CD2 3.35Å; H512-F514 WeakPolarHBondContact O-CE2 3.48Å; H512-F514 PolarHBondContact O-N 3.45Å
513	K	66.8	Low	64.8	Low	148 Å²	148	130.1 Å²	130.1	64%	0.643	67%	0.672	S	S	*	*			trans	-82.1	103.1	174.7	-69.4	-175.5	178.8	-169.7	0	109.4	K510 V515	K510-K513 HydrophobicContact CB-CD 4.42Å; K510-K513 HydrophobicContact CG-CD 4.34Å; K510-K513 WeakPolarHBondContact O-CB 3.48Å; K510-K513 PolarHBondContact O-N 3.3Å; K510-K513 VanDerWaalsContact O-N 3.09Å; K513-V515 PolarHBondContact O-N 3.48Å
514	F	67.7	Low	63.3	Low	188 Å²	188	135.3 Å²	135.3	83%	0.825	70%	0.698	S	S	*	*			trans	-74.4	120.4	170.2	-57.7	-82	0	0	0	109.1	H512 L516	H512-F514 WeakPolarHBondContact O-CD2 3.35Å; H512-F514 WeakPolarHBondContact O-CE2 3.48Å; H512-F514 PolarHBondContact O-N 3.45Å; F514-L516 PolarHBondContact O-N 2.84Å
515	V	66.5	Low	62.8	Low	126 Å²	126	137.3 Å²	137.3	76%	0.764	71%	0.711	S	S	*	*			trans	-75.6	103.4	167	178.8	0	0	0	0	106.9	K513 R517	K513-V515 PolarHBondContact O-N 3.48Å; V515-R517 VanDerWaalsContact C-N 3.32Å; V515-R517 HydrophobicContact CG1-CG 4.3Å; V515-R517 PolarHBondContact O-N 2.98Å
516	L	56.6	Low	61.9	Low	147 Å²	147	135.3 Å²	135.3	77%	0.77	71%	0.705	S	S	*	*			trans	-66.4	94.9	167.8	-119.1	148.4	0	0	0	107.3	F514 L518	F514-L516 PolarHBondContact O-N 2.84Å; L516-L518 VanDerWaalsContact C-N 3.29Å; L516-L518 HydrophobicContact CB-CD1 4.38Å; L516-L518 HydrophobicContact CD2-CD1 4.24Å; L516-L518 PolarHBondContact O-N 3.43Å
517	R	55.9	Low	61	Low	224 Å²	224	134.3 Å²	134.3	85%	0.845	71%	0.707	S	S	*	*			trans	-72.5	90.7	167.1	-74.6	-169.9	176.6	175.8	-0.1	107.1	V515 Q519	V515-R517 VanDerWaalsContact C-N 3.32Å; V515-R517 HydrophobicContact CG1-CG 4.3Å; V515-R517 PolarHBondContact O-N 2.98Å; R517-Q519 PolarHBondContact O-N 3Å
518	L	60.1	Low	60.2	Low	145 Å²	145	136.4 Å²	136.4	76%	0.759	72%	0.719	S	S	*	*			trans	-64.6	107.1	160.8	-78	97.2	0	0	0	106.6	L516 S520	L516-L518 VanDerWaalsContact C-N 3.29Å; L516-L518 HydrophobicContact CB-CD1 4.38Å; L516-L518 HydrophobicContact CD2-CD1 4.24Å; L516-L518 PolarHBondContact O-N 3.43Å; L518-S520 VanDerWaalsContact C-N 3.33Å; L518-S520 PolarHBondContact O-N 3.2Å
519	Q	53.6	Low	59.4	Low	169 Å²	169	141.3 Å²	141.3	79%	0.79	74%	0.744	S	S	*	*			trans	-64.5	102.6	161	-76.9	-178	-40.2	0	0	106	R517 E521	R517-Q519 PolarHBondContact O-N 3Å; Q519-E521 PolarHBondContact O-N 3.42Å
520	S	60.8	Low	58.5	Low	108 Å²	108	144.6 Å²	144.6	76%	0.755	75%	0.754	S	S	*	*			trans	-74.3	65.8	169.1	59.3	0	0	0	0	108.9	L518 T522	L518-S520 VanDerWaalsContact C-N 3.33Å; L518-S520 PolarHBondContact O-N 3.2Å; S520-T522 PolarHBondContact O-N 2.8Å
521	E	56.8	Low	57.9	Low	167 Å²	167	148.4 Å²	148.4	78%	0.78	78%	0.78	S	S	*	*			trans	-87.5	66.5	159.3	-73.5	-171.3	-177.9	0	0	108.2	Q519	Q519-E521 PolarHBondContact O-N 3.42Å
522	T	49.5	Very low	57.2	Low	131 Å²	131	154 Å²	154	80%	0.804	80%	0.799	S	S	*	*			trans	-147.2	92.1	149.4	34.4	0	0	0	0	106.6	S520	S520-T522 PolarHBondContact O-N 2.8Å
523	S	45.2	Very low	56.6	Low	112 Å²	112	157 Å²	157	78%	0.783	82%	0.82	S	S	*	*			trans	-70.6	123.9	162.2	50.9	0	0	0	0	109.1
524	V	39.8	Very low	55.7	Low	219 Å²	219	157.8 Å²	157.8	100%	1.327	84%	0.837	S	S	*	*			trans	56.7	0	162.6	-172.3	0	0	0	0	117.3

Retrieved 524 of 524 residues in 235.2 ms (Link to these results)

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