A0A096NA21_PAPAN Loading...

G protein-coupled receptor 63

Orphan receptor. May play a role in brain function.

AlphaFold DB , UniProt , Accession A0A096NA21, Species PAPAN (Papio anubis, Olive baboon), Gene GPR63, Length 419 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.1	Very low	26.8	Very low	236 Å²	236	158.1 Å²	158.1	100%	1.163	86%	0.857	S	S	*	*				0	81.6	0	-70.1	173.7	178.8	0	0	106.4
2	V	25.6	Very low	26.9	Very low	133 Å²	133	155.9 Å²	155.9	81%	0.806	85%	0.853	S	S	*	*				38.2	95.2	69	-169.9	0	0	0	0	111.9
3	F	25.9	Very low	27	Very low	217 Å²	217	149.8 Å²	149.8	95%	0.952	85%	0.848	S	S	*	*				-148.3	137.4	129.3	-108.2	-80.2	0	0	0	109.2
4	S	23.3	Very low	27.1	Very low	106 Å²	106	149.1 Å²	149.1	74%	0.741	85%	0.849	S	S	*	*			trans	-121.4	162.7	-169.4	-165.6	0	0	0	0	109.2
5	A	27.3	Very low	27.2	Very low	88 Å²	88	146.5 Å²	146.5	73%	0.727	84%	0.843	S	S	*	*			trans	68.4	142.2	163.4	0	0	0	0	0	116.5
6	V	26.8	Very low	27.4	Very low	124 Å²	124	147.8 Å²	147.8	75%	0.752	85%	0.847	S	S	*	*				-154.1	131	56.4	167.3	0	0	0	0	111.3	T8	V6-T8 HydrophobicContact CG1-CG2 4.2Å
7	L	24.6	Very low	27.5	Very low	170 Å²	170	145.9 Å²	145.9	89%	0.89	84%	0.839	S	S	*	*			trans	-77.9	134.2	156.9	-99.3	118.3	0	0	0	109.1
8	T	26.7	Very low	27.5	Very low	130 Å²	130	145.8 Å²	145.8	80%	0.798	84%	0.841	S	S	*	*			trans	-124.9	127.1	155.2	38.4	0	0	0	0	109.8	V6	V6-T8 HydrophobicContact CG1-CG2 4.2Å
9	A	27.9	Very low	27.5	Very low	100 Å²	100	148.1 Å²	148.1	83%	0.826	84%	0.841	S	S	*	*			trans	-63.8	142.1	-179.2	0	0	0	0	0	112.5
10	F	25.3	Very low	27.5	Very low	213 Å²	213	146.5 Å²	146.5	93%	0.934	83%	0.833	S	S	*	*			trans	-118.1	126	161.4	-137.6	-91.6	0	0	0	109.4
11	R	27.6	Very low	27.4	Very low	222 Å²	222	145.4 Å²	145.4	84%	0.838	83%	0.83	S	S	*	*			trans	-79.9	134	-178.8	-127.4	-178.6	-168	-170.4	2.2	110
12	T	28.3	Very low	27.1	Very low	132 Å²	132	143.6 Å²	143.6	81%	0.81	81%	0.811	S	S	*	*			trans	22.5	118.1	144.1	56.3	0	0	0	0	119.5
13	G	27.4	Very low	27.2	Very low	77 Å²	77	145.6 Å²	145.6	79%	0.794	81%	0.812	S	S	*	*			trans	-174.4	92.3	163.4	0	0	0	0	0	112.1
14	T	29.1	Very low	27.2	Very low	139 Å²	139	141.8 Å²	141.8	85%	0.853	80%	0.802	S	S	*	*			trans	-20.1	128.4	170	50.3	0	0	0	0	118.3
15	S	29	Very low	27.4	Very low	110 Å²	110	143.4 Å²	143.4	77%	0.769	81%	0.807	S	S	*	*				-179.6	120.5	129.2	29.8	0	0	0	0	113
16	N	30	Very low	27.4	Very low	168 Å²	168	149.5 Å²	149.5	90%	0.898	81%	0.813	S	S	*	*			trans	16.5	105.1	156.4	-64.8	-9.4	0	0	0	119.2
17	T	29.4	Very low	27.4	Very low	115 Å²	115	152.9 Å²	152.9	71%	0.706	82%	0.823	S	S	*	*			trans	-139	119	153.2	35.9	0	0	0	0	110.2	F19	T17-F19 PolarHBondContact O-N 2.8Å
18	T	27.6	Very low	27.4	Very low	144 Å²	144	152.8 Å²	152.8	88%	0.883	82%	0.823	S	S	*	*			trans	-69.7	117.7	170.8	32.2	0	0	0	0	109.3
19	F	26.6	Very low	27.6	Very low	190 Å²	190	153.8 Å²	153.8	83%	0.833	82%	0.822	S	S	*	*			trans	-84.4	122.2	170.8	-74.7	-90	0	0	0	109.7	T17	T17-F19 PolarHBondContact O-N 2.8Å
20	V	27.8	Very low	27.5	Very low	115 Å²	115	155.3 Å²	155.3	70%	0.697	82%	0.821	S	S	*	*			trans	-95	114.1	163.2	176.5	0	0	0	0	107	Y22	V20-Y22 HydrophobicContact CG1-CD2 4.15Å; V20-Y22 HydrophobicContact CG1-CE2 3.87Å
21	V	25.7	Very low	27.8	Very low	125 Å²	125	151.1 Å²	151.1	76%	0.758	81%	0.813	S	S	*	*			trans	-76.9	123.5	175.6	176.5	0	0	0	0	108.6
22	Y	26.6	Very low	28.1	Very low	198 Å²	198	146 Å²	146	78%	0.776	81%	0.808	S	S	*	*			trans	-107.6	110.3	162.3	-85.2	-88.4	0	0	0	108.2	V20	V20-Y22 HydrophobicContact CG1-CD2 4.15Å; V20-Y22 HydrophobicContact CG1-CE2 3.87Å
23	E	28.2	Very low	28.7	Very low	175 Å²	175	144.9 Å²	144.9	82%	0.818	80%	0.803	S	S	*	*			trans	-76.9	114.2	166.4	-117.4	178.3	166.5	0	0	108.4
24	N	26.2	Very low	28.8	Very low	137 Å²	137	147.3 Å²	147.3	73%	0.733	81%	0.805	S	S	*	*			trans	-114	104	167.7	-91	-14.4	0	0	0	108.2
25	T	27.9	Very low	28.7	Very low	139 Å²	139	150 Å²	150	85%	0.853	81%	0.805	S	S	*	*			trans	-79.8	121.1	169.9	24.3	0	0	0	0	110.1
26	Y	26.7	Very low	28.6	Very low	216 Å²	216	153.9 Å²	153.9	85%	0.847	81%	0.811	S	S	*	*			trans	-80.4	139.9	167	-72.4	-97.2	0	0	0	109.7
27	M	27.9	Very low	28.5	Very low	196 Å²	196	154.7 Å²	154.7	97%	0.966	81%	0.809	S	S	*	*			trans	-152.2	139.3	143	-117.3	-168.1	-76.2	0	0	113.6
28	N	24.4	Very low	28.9	Very low	168 Å²	168	153.8 Å²	153.8	90%	0.898	81%	0.806	S	S	*	*			trans	-79.2	160.2	-170.4	-104	-20.6	0	0	0	113.9
29	I	31	Very low	28.8	Very low	150 Å²	150	153.6 Å²	153.6	77%	0.769	80%	0.799	S	S	*	*			trans	-73.9	145.6	175	-65.7	161.7	0	0	0	112.1
30	T	25.8	Very low	28.9	Very low	133 Å²	133	151.8 Å²	151.8	82%	0.816	80%	0.796	S	S	*	*			trans	-168.2	103.2	141.7	14.8	0	0	0	0	113.9
31	V	30.3	Very low	28.8	Very low	125 Å²	125	151.3 Å²	151.3	76%	0.758	80%	0.798	S	S	*	*				54	146.8	127.2	-177.9	0	0	0	0	121
32	P	35.3	Very low	29.4	Very low	113 Å²	113	150.4 Å²	150.4	73%	0.734	80%	0.795	S	S	*	*			cis	-137.4	-160.7	-38	46.2	-24.1	0	0	0	112.3
33	P	39.2	Very low	29.4	Very low	109 Å²	109	148.7 Å²	148.7	71%	0.708	80%	0.798	S	S	*	*			trans	-102.3	-178.8	-151.1	45.1	-41.3	0	0	0	116.4
34	P	29.2	Very low	29.3	Very low	128 Å²	128	148.5 Å²	148.5	83%	0.831	80%	0.802	S	S	*	*				-136.6	154.1	123.9	34.2	-19.2	0	0	0	115.4
35	F	28	Very low	29.2	Very low	196 Å²	196	152.9 Å²	152.9	86%	0.86	81%	0.808	S	S	*	*			trans	-55.3	137.1	171.8	-87	-108	0	0	0	114.1
36	Q	26.3	Very low	29	Very low	192 Å²	192	156.1 Å²	156.1	90%	0.897	81%	0.806	S	S	*	*				-174.2	128.1	126.9	-115.9	160.9	-27.8	0	0	112.8
37	H	28.6	Very low	28.8	Very low	184 Å²	184	150.8 Å²	150.8	85%	0.852	80%	0.8	S	S	*	*			trans	-110.1	168.3	153.6	-102.2	-53.2	0	0	0	106.6
38	P	37.6	Very low	28.7	Very low	97 Å²	97	150.7 Å²	150.7	63%	0.63	80%	0.795	S	S	*	*			cis	-136.4	-172.3	7.1	29.8	-5	0	0	0	114.4
39	D	25.4	Very low	28.7	Very low	139 Å²	139	150.5 Å²	150.5	74%	0.743	79%	0.789	S	S	*	*			trans	104.1	124.9	142.3	-75.7	-18.3	0	0	0	123
40	I	28.4	Very low	28.5	Very low	152 Å²	152	149.3 Å²	149.3	78%	0.779	79%	0.789	S	S	*	*			trans	84.7	105.7	143.9	-58.5	155.8	0	0	0	119.2
41	S	26.5	Very low	28.5	Very low	105 Å²	105	152.4 Å²	152.4	73%	0.734	80%	0.796	S	S	*	*			trans	-68.4	151.1	148.7	57.1	0	0	0	0	110.5
42	P	37.9	Very low	28.5	Very low	107 Å²	107	150.8 Å²	150.8	70%	0.695	80%	0.796	S	S	*	*				-154.7	168.3	68.2	38.7	-17.1	0	0	0	117.9
43	L	26.3	Very low	28.6	Very low	162 Å²	162	151.1 Å²	151.1	85%	0.848	80%	0.798	S	S	*	*			trans	42.9	108.3	144.7	-75.9	160	0	0	0	119.1
44	L	26.7	Very low	28.3	Very low	170 Å²	170	152.7 Å²	152.7	89%	0.89	81%	0.806	S	S	*	*			trans	-141.1	113	142.1	-101.8	168.7	0	0	0	111.5
45	R	23.8	Very low	28.3	Very low	229 Å²	229	150.5 Å²	150.5	86%	0.864	81%	0.807	S	S	*	*			trans	-50.5	133	152.2	-99.9	174.2	-171.1	-157	2.6	109
46	Y	23.7	Very low	28.5	Very low	208 Å²	208	149.3 Å²	149.3	82%	0.816	81%	0.808	S	S	*	*			trans	-151.4	109	144.5	-130.5	-93.2	0	0	0	110.1	F48	Y46-F48 HydrophobicContact CD1-CD2 4.33Å; Y46-F48 AromaticContact CE1-CD2 3.98Å; Y46-F48 HydrophobicContact CE1-CD2 3.98Å; Y46-F48 HydrophobicContact CE1-CE2 4.39Å
47	S	22.2	Very low	28.7	Very low	103 Å²	103	145.5 Å²	145.5	72%	0.72	80%	0.803	S	S	*	*			trans	-76.4	136.1	160.4	44.6	0	0	0	0	109.1
48	F	25.2	Very low	28.8	Very low	194 Å²	194	142 Å²	142	85%	0.851	80%	0.8	S	S	*	*			trans	-144.5	136.8	152.5	-131.2	-92.5	0	0	0	110	Y46	Y46-F48 HydrophobicContact CD1-CD2 4.33Å; Y46-F48 AromaticContact CE1-CD2 3.98Å; Y46-F48 HydrophobicContact CE1-CD2 3.98Å; Y46-F48 HydrophobicContact CE1-CE2 4.39Å
49	E	26	Very low	28.5	Very low	165 Å²	165	145.3 Å²	145.3	77%	0.771	81%	0.811	S	S	*	*			trans	-85.1	165.1	-167.8	-65.4	176.9	133.6	0	0	113.7
50	T	25.3	Very low	28.7	Very low	125 Å²	125	144.9 Å²	144.9	77%	0.767	81%	0.813	S	S	*	*			trans	61.3	113.1	141.4	43.3	0	0	0	0	121.4
51	M	26.2	Very low	28.9	Very low	197 Å²	197	144 Å²	144	97%	0.97	81%	0.814	S	S	*	*				-159.1	121	117.6	-106	-179.7	-149.5	0	0	110.5
52	A	30.1	Very low	29.4	Very low	91 Å²	91	146.8 Å²	146.8	75%	0.752	82%	0.822	S	S	*	*			trans	-110.8	154	161.2	0	0	0	0	0	108.2
53	P	38.4	Very low	29.3	Very low	120 Å²	120	146.3 Å²	146.3	78%	0.779	82%	0.82	S	S	*	*				-136.1	131.1	118.7	29.3	-13.4	0	0	0	114
54	T	31.9	Very low	29.8	Very low	143 Å²	143	145 Å²	145	88%	0.877	82%	0.819	S	S	*	*			trans	13.3	126	145.1	51.7	0	0	0	0	121.2
55	G	30.5	Very low	30.2	Very low	82 Å²	82	141.2 Å²	141.2	85%	0.845	81%	0.813	S	S	*	*			trans	-164.7	105	153.6	0	0	0	0	0	110.6
56	L	31.9	Very low	30.9	Very low	170 Å²	170	135.8 Å²	135.8	89%	0.89	81%	0.805	S	S	*	*			trans	-84.8	128.6	-170.6	-172.3	80.3	0	0	0	112.1
57	S	30.8	Very low	31.5	Very low	112 Å²	112	131.1 Å²	131.1	78%	0.783	80%	0.8	S	S	*	*			trans	-166.6	117.3	142.7	-0.1	0	0	0	0	113.6
58	S	29.1	Very low	32.1	Very low	112 Å²	112	132.9 Å²	132.9	78%	0.783	81%	0.807	S	S	*	*			trans	53.9	105.5	147.9	59.7	0	0	0	0	121.8
59	L	32.7	Very low	32.6	Very low	166 Å²	166	129.4 Å²	129.4	87%	0.869	80%	0.802	S	S	*	*			trans	-56.8	143.2	141.5	-70	118.8	0	0	0	109.1
60	T	29.5	Very low	33.4	Very low	129 Å²	129	127.3 Å²	127.3	79%	0.791	80%	0.802	S	S	*	*				-165.8	125.2	71.5	38	0	0	0	0	111.1
61	V	31.7	Very low	33.9	Very low	133 Å²	133	125.5 Å²	125.5	81%	0.806	80%	0.8	S	S	*	*			trans	-126	103.6	155.3	177	0	0	0	0	107	S63	V61-S63 PolarHBondContact O-N 2.93Å
62	N	37	Very low	34.5	Very low	165 Å²	165	120.8 Å²	120.8	88%	0.882	79%	0.792	S	S	*	*			trans	-62	105.1	164.5	-102.1	-6.6	0	0	0	107.8
63	S	36.3	Very low	35.2	Very low	96 Å²	96	125.1 Å²	125.1	67%	0.671	79%	0.794	S	S	*	*			trans	-122.6	95.3	159.3	-72.2	0	0	0	0	106.6	V61 A65	V61-S63 PolarHBondContact O-N 2.93Å; S63-A65 PolarHBondContact O-N 3.35Å
64	T	36.3	Very low	35.8	Very low	134 Å²	134	127.7 Å²	127.7	82%	0.822	79%	0.793	S	S	*	*			trans	-58.5	89.4	156.7	34.7	0	0	0	0	107.2	V66	T64-V66 PolarHBondContact O-N 2.85Å
65	A	36.6	Very low	37.1	Very low	91 Å²	91	125.3 Å²	125.3	75%	0.752	78%	0.782	S	S	*	*			trans	-66.6	90.4	167.1	0	0	0	0	0	107.3	S63	S63-A65 PolarHBondContact O-N 3.35Å
66	V	37.6	Very low	39	Very low	115 Å²	115	124.4 Å²	124.4	70%	0.697	76%	0.758	S	S	*	*			trans	-54.4	127.1	159.7	176.7	0	0	0	0	106.3	T64 T68	T64-V66 PolarHBondContact O-N 2.85Å; V66-T68 PolarHBondContact O-N 3.15Å
67	P	36.7	Very low	41.4	Very low	111 Å²	111	121.9 Å²	121.9	72%	0.721	75%	0.745	S	S	*	*			trans	-60.8	113.6	170.8	-10.7	23.9	0	0	0	106.6	T69	P67-T69 VanDerWaalsContact C-N 3.33Å; P67-T69 PolarHBondContact O-N 3.15Å
68	T	34.8	Very low	44	Very low	140 Å²	140	122 Å²	122	86%	0.859	74%	0.737	S	S	*	*			trans	-57.5	101.1	168.3	29.2	0	0	0	0	107.4	V66	V66-T68 PolarHBondContact O-N 3.15Å
69	T	36.1	Very low	46.8	Very low	121 Å²	121	120.9 Å²	120.9	74%	0.742	73%	0.726	S	S	*	*			trans	-55.4	136.1	167.5	37.1	0	0	0	0	108.5	P67 A71	P67-T69 VanDerWaalsContact C-N 3.33Å; P67-T69 PolarHBondContact O-N 3.15Å; T69-A71 PolarHBondContact O-N 3.2Å
70	P	41.5	Very low	49.4	Very low	121 Å²	121	116.3 Å²	116.3	79%	0.786	70%	0.703	S	S	*	*	S	Bend	trans	-59	134.5	175.1	22.6	-29.1	0	0	0	108.7	A72	P70-A72 PolarHBondContact O-N 3.38Å; P70-A72 VanDerWaalsContact O-N 3.15Å
71	A	37.2	Very low	52.1	Low	87 Å²	87	111.6 Å²	111.6	72%	0.719	67%	0.672	S	S	*	*			trans	-20.4	109.4	-178.8	0	0	0	0	0	113.4	T69 F73	T69-A71 PolarHBondContact O-N 3.2Å; A71-F73 PolarHBondContact O-N 3.17Å
72	A	37.7	Very low	55	Low	97 Å²	97	110.2 Å²	110.2	80%	0.802	66%	0.659	S	S	*	*			trans	-53.8	106	173.4	0	0	0	0	0	109	P70 K74	P70-A72 PolarHBondContact O-N 3.38Å; P70-A72 VanDerWaalsContact O-N 3.15Å; A72-K74 PolarHBondContact O-N 3.45Å
73	F	44.9	Very low	57.5	Low	182 Å²	182	106 Å²	106	80%	0.798	64%	0.639	S	S	*	*			trans	-54.7	109.9	163.7	-73.9	-93.7	0	0	0	106.4	A71 S75	A71-F73 PolarHBondContact O-N 3.17Å; F73-S75 PolarHBondContact O-N 2.97Å
74	K	50.9	Low	60.1	Low	174 Å²	174	102.2 Å²	102.2	76%	0.757	61%	0.611	S	S	*	*			trans	-63.4	88.5	163.3	-99.8	-177.1	175.6	178.4	0	106.6	A72 L76	A72-K74 PolarHBondContact O-N 3.45Å; K74-L76 PolarHBondContact O-N 3.08Å
75	S	60.3	Low	62.7	Low	93 Å²	93	96.3 Å²	96.3	65%	0.65	58%	0.575	S	S	*	*	P	Polyproline II helix	trans	-58.2	129.1	167.1	50.7	0	0	0	0	107.3	F73 N77	F73-S75 PolarHBondContact O-N 2.97Å; S75-N77 PolarHBondContact O-N 3.28Å
76	L	68.5	Low	65.5	Low	64 Å²	64	94.6 Å²	94.6	34%	0.335	56%	0.561	S	S	.	*	P	Polyproline II helix	trans	-52.5	136.9	171	-157.7	70.4	0	0	0	108.4	K74 L78 L80 Q81 L84	K74-L76 PolarHBondContact O-N 3.08Å; L76-L78 PolarHBondContact O-N 3.35Å; L76-L78 VanDerWaalsContact O-N 3.12Å; L76-L80 HydrophobicContact CD1-CD2 3.81Å; L76-L80 HydrophobicContact CD2-CD2 4.41Å; L76-L80 HydrophobicContact CD2-CG 4.33Å; L76-L80 HydrophobicContact CG-CD2 3.92Å; L76-L80 HydrophobicContact CG-CG 4.22Å; L76-Q81 HydrophobicContact CD2-CB 4.15Å; L76-Q81 HydrophobicContact CD2-CG 4.42Å; L76-L84 HydrophobicContact CD2-CD1 3.69Å
77	N	83.4	Confident	68.2	Low	117 Å²	117	92.6 Å²	92.6	63%	0.626	55%	0.546	S	S	*	.	P	Polyproline II helix	trans	-51.2	125.6	179.4	-69.1	-28.5	0	0	0	109.1	S75 P79 L80 Q81	S75-N77 PolarHBondContact O-N 3.28Å; N77-P79 VanDerWaalsContact C-CD 3.43Å; N77-P79 VanDerWaalsContact C-N 3.32Å; N77-P79 HydrophobicContact CB-CG 4.36Å; N77-L80 HydrophobicContact CB-CB 4.06Å; N77-L80 WeakPolarHBondContact O-CA 3.45Å; N77-L80 VanDerWaalsContact O-CB 3.29Å; N77-L80 WeakPolarHBondContact O-CB 3.35Å; N77-L80 PolarHBondContact O-N 2.83Å; N77-Q81 PolarHBondContact O-N 3.21Å
78	L	84.4	Confident	70.9	Confident	115 Å²	115	87.4 Å²	87.4	60%	0.602	51%	0.512	S	S	*	.	H	α-helix	trans	-46.5	-46.8	-178.7	-174.8	65.1	0	0	0	113.8	L76 L80 Q81 I82	L76-L78 PolarHBondContact O-N 3.35Å; L76-L78 VanDerWaalsContact O-N 3.12Å; L78-L80 VanDerWaalsContact C-N 3.32Å; L78-L80 PolarHBondContact O-N 2.92Å; L78-Q81 PolarHBondContact O-N 3.14Å; L78-I82 HydrophobicContact CD1-CD1 4.31Å; L78-I82 HydrophobicContact CG-CD1 4.01Å; L78-I82 VanDerWaalsContact O-CG1 3.31Å; L78-I82 WeakPolarHBondContact O-CG1 3.38Å; L78-I82 PolarHBondContact O-N 3.34Å
79	P	88.6	Confident	73.8	Confident	87 Å²	87	85 Å²	85	57%	0.565	49%	0.493	S	S	*	.	H	α-helix	trans	-64.2	-34.9	177.1	24.5	-35.5	0	0	0	113.5	N77 T83	N77-P79 VanDerWaalsContact C-CD 3.43Å; N77-P79 VanDerWaalsContact C-N 3.32Å; N77-P79 HydrophobicContact CB-CG 4.36Å; P79-T83 WeakPolarHBondContact O-CB 3.22Å; P79-T83 PolarHBondContact O-N 3.5Å; P79-T83 PolarHBondContact O-OG1 2.9Å
80	L	86.6	Confident	76.7	Confident	71 Å²	71	85.9 Å²	85.9	37%	0.372	49%	0.486	S	S	.	.	H	α-helix	trans	-66.3	-45.6	175	177.8	62	0	0	0	110.1	L76 N77 L78 I82 T83 L84	L76-L80 HydrophobicContact CD1-CD2 3.81Å; L76-L80 HydrophobicContact CD2-CD2 4.41Å; L76-L80 HydrophobicContact CD2-CG 4.33Å; L76-L80 HydrophobicContact CG-CD2 3.92Å; L76-L80 HydrophobicContact CG-CG 4.22Å; N77-L80 HydrophobicContact CB-CB 4.06Å; N77-L80 WeakPolarHBondContact O-CA 3.45Å; N77-L80 VanDerWaalsContact O-CB 3.29Å; N77-L80 WeakPolarHBondContact O-CB 3.35Å; N77-L80 PolarHBondContact O-N 2.83Å; L78-L80 VanDerWaalsContact C-N 3.32Å; L78-L80 PolarHBondContact O-N 2.92Å; L80-I82 PolarHBondContact O-N 3.29Å; L80-T83 PolarHBondContact O-N 2.88Å; L80-L84 HydrophobicContact CD1-CD1 4.16Å; L80-L84 HydrophobicContact CD1-CG 4.14Å; L80-L84 HydrophobicContact CG-CD1 4.01Å; L80-L84 HydrophobicContact CG-CG 4.4Å; L80-L84 WeakPolarHBondContact O-CB 3.33Å; L80-L84 VanDerWaalsContact O-CG 3.22Å; L80-L84 WeakPolarHBondContact O-CG 3.49Å; L80-L84 PolarHBondContact O-N 3.48Å
81	Q	87.4	Confident	79.2	Confident	30 Å²	30	80.5 Å²	80.5	14%	0.14	45%	0.451	C	S	.	.	H	α-helix	trans	-61.3	-41.6	178.2	-166.5	-179.7	17.4	0	0	112.6	L76 N77 L78 L84 S85 I142 L143	L76-Q81 HydrophobicContact CD2-CB 4.15Å; L76-Q81 HydrophobicContact CD2-CG 4.42Å; N77-Q81 PolarHBondContact O-N 3.21Å; L78-Q81 PolarHBondContact O-N 3.14Å; Q81-L84 PolarHBondContact O-N 2.91Å; Q81-S85 WeakPolarHBondContact O-CB 3.5Å; Q81-S85 PolarHBondContact O-N 3.43Å; Q81-S85 PolarHBondContact O-OG 3.38Å; Q81-I142 PolarHBondContact NE2-O 3.33Å; Q81-L143 VanDerWaalsContact NE2-C 3.31Å; Q81-L143 PolarHBondContact NE2-O 3.28Å
82	I	91.4	Very high	82.1	Confident	104 Å²	104	78.4 Å²	78.4	53%	0.533	43%	0.428	S	S	.	.	H	α-helix	trans	-62.3	-48.7	175.3	-68.6	166.2	0	0	0	110.2	L78 L80 L84 S85 A86	L78-I82 HydrophobicContact CD1-CD1 4.31Å; L78-I82 HydrophobicContact CG-CD1 4.01Å; L78-I82 VanDerWaalsContact O-CG1 3.31Å; L78-I82 WeakPolarHBondContact O-CG1 3.38Å; L78-I82 PolarHBondContact O-N 3.34Å; L80-I82 PolarHBondContact O-N 3.29Å; I82-L84 VanDerWaalsContact C-N 3.33Å; I82-L84 PolarHBondContact O-N 3.23Å; I82-S85 PolarHBondContact O-N 3.47Å; I82-A86 WeakPolarHBondContact O-CB 3.41Å; I82-A86 PolarHBondContact O-N 3.27Å
83	T	90.9	Very high	84.9	Confident	77 Å²	77	79.7 Å²	79.7	47%	0.472	42%	0.415	S	S	.	.	H	α-helix	trans	-59.1	-46.4	179.7	-57.8	0	0	0	0	110.9	P79 L80 A86 I87	P79-T83 WeakPolarHBondContact O-CB 3.22Å; P79-T83 PolarHBondContact O-N 3.5Å; P79-T83 PolarHBondContact O-OG1 2.9Å; L80-T83 PolarHBondContact O-N 2.88Å; T83-A86 PolarHBondContact O-N 3.25Å; T83-I87 HydrophobicContact CG2-CD1 4.03Å; T83-I87 VanDerWaalsContact O-CG1 3.31Å; T83-I87 WeakPolarHBondContact O-CG1 3.48Å; T83-I87 PolarHBondContact O-N 3.47Å
84	L	90.1	Very high	87.3	Confident	16 Å²	16	72.3 Å²	72.3	8%	0.084	39%	0.385	C	S	.	.	H	α-helix	trans	-63.2	-44.8	178.7	-70.6	175.8	0	0	0	112	L76 L80 Q81 I82 A86 I87 M88 I142 W355 W358	L76-L84 HydrophobicContact CD2-CD1 3.69Å; L80-L84 HydrophobicContact CD1-CD1 4.16Å; L80-L84 HydrophobicContact CD1-CG 4.14Å; L80-L84 HydrophobicContact CG-CD1 4.01Å; L80-L84 HydrophobicContact CG-CG 4.4Å; L80-L84 WeakPolarHBondContact O-CB 3.33Å; L80-L84 VanDerWaalsContact O-CG 3.22Å; L80-L84 WeakPolarHBondContact O-CG 3.49Å; L80-L84 PolarHBondContact O-N 3.48Å; Q81-L84 PolarHBondContact O-N 2.91Å; I82-L84 VanDerWaalsContact C-N 3.33Å; I82-L84 PolarHBondContact O-N 3.23Å; L84-A86 VanDerWaalsContact C-N 3.3Å; L84-A86 PolarHBondContact O-N 3.43Å; L84-I87 PolarHBondContact O-N 3.16Å; L84-M88 PolarHBondContact O-N 3.1Å; L84-I142 HydrophobicContact CB-CG2 4.4Å; L84-W355 HydrophobicContact CD2-CH2 3.31Å; L84-W355 HydrophobicContact CD2-CZ2 3.96Å; L84-W355 HydrophobicContact CD2-CZ3 3.88Å; L84-W358 HydrophobicContact CB-CH2 3.58Å; L84-W358 HydrophobicContact CB-CZ2 3.97Å; L84-W358 HydrophobicContact CD2-CH2 3.44Å; L84-W358 VanDerWaalsContact CD2-CH2 3.44Å; L84-W358 HydrophobicContact CD2-CZ2 4.04Å; L84-W358 HydrophobicContact CD2-CZ3 4Å; L84-W358 HydrophobicContact CG-CH2 4.07Å; L84-W358 HydrophobicContact CG-CZ2 4.48Å; L84-W358 WeakPolarHBondContact O-CH2 3.1Å
85	S	92	Very high	89.5	Confident	10 Å²	10	64 Å²	64	7%	0.07	35%	0.349	C	S	.	.	H	α-helix	trans	-61	-42.5	178.3	-57.1	0	0	0	0	111.1	Q81 I82 I87 M88 I89 L143	Q81-S85 WeakPolarHBondContact O-CB 3.5Å; Q81-S85 PolarHBondContact O-N 3.43Å; Q81-S85 PolarHBondContact O-OG 3.38Å; I82-S85 PolarHBondContact O-N 3.47Å; S85-I87 PolarHBondContact O-N 3.09Å; S85-M88 PolarHBondContact O-N 3.16Å; S85-I89 WeakPolarHBondContact O-CD1 3.42Å; S85-I89 VanDerWaalsContact O-CG1 3.23Å; S85-I89 WeakPolarHBondContact O-CG1 3.3Å; S85-I89 PolarHBondContact O-N 3.11Å; S85-L143 VanDerWaalsContact OG-CD2 3.3Å; S85-L143 WeakPolarHBondContact OG-CD2 3.4Å
86	A	94.4	Very high	91.2	Very high	55 Å²	55	63.2 Å²	63.2	46%	0.455	33%	0.334	S	S	.	.	H	α-helix	trans	-61.5	-43.4	175.9	0	0	0	0	0	112.4	I82 T83 L84 I89 F90	I82-A86 WeakPolarHBondContact O-CB 3.41Å; I82-A86 PolarHBondContact O-N 3.27Å; T83-A86 PolarHBondContact O-N 3.25Å; L84-A86 VanDerWaalsContact C-N 3.3Å; L84-A86 PolarHBondContact O-N 3.43Å; A86-I89 PolarHBondContact O-N 2.96Å; A86-F90 PolarHBondContact O-N 3.43Å
87	I	94.1	Very high	92.5	Very high	72 Å²	72	63.8 Å²	63.8	37%	0.369	34%	0.337	S	S	.	.	H	α-helix	trans	-63.5	-43.5	176.6	-65	163.9	0	0	0	110.9	T83 L84 S85 F90 I91 W358	T83-I87 HydrophobicContact CG2-CD1 4.03Å; T83-I87 VanDerWaalsContact O-CG1 3.31Å; T83-I87 WeakPolarHBondContact O-CG1 3.48Å; T83-I87 PolarHBondContact O-N 3.47Å; L84-I87 PolarHBondContact O-N 3.16Å; S85-I87 PolarHBondContact O-N 3.09Å; I87-F90 WeakPolarHBondContact O-CB 3.34Å; I87-F90 PolarHBondContact O-N 2.96Å; I87-I91 HydrophobicContact CG2-CD1 3.9Å; I87-I91 HydrophobicContact CG2-CG1 4.4Å; I87-I91 WeakPolarHBondContact O-CG1 3.49Å; I87-I91 PolarHBondContact O-N 3.46Å; I87-W358 HydrophobicContact CB-CH2 4.29Å; I87-W358 HydrophobicContact CB-CZ3 3.75Å; I87-W358 HydrophobicContact CG2-CE3 4.14Å; I87-W358 HydrophobicContact CG2-CH2 4.47Å; I87-W358 HydrophobicContact CG2-CZ3 3.5Å
88	M	93.5	Very high	93	Very high	2 Å²	2	59 Å²	59	1%	0.01	32%	0.315	C	S	.	.	H	α-helix	trans	-64.4	-40.7	177.6	-80.9	-63.3	-64.6	0	0	112.8	L84 S85 F90 I91 L92 A138 L139 I142 W358 Y361	L84-M88 PolarHBondContact O-N 3.1Å; S85-M88 PolarHBondContact O-N 3.16Å; M88-F90 VanDerWaalsContact C-N 3.29Å; M88-F90 PolarHBondContact O-N 3.22Å; M88-I91 PolarHBondContact O-N 3.38Å; M88-L92 VanDerWaalsContact O-CB 3.24Å; M88-L92 WeakPolarHBondContact O-CB 3.33Å; M88-L92 PolarHBondContact O-N 2.92Å; M88-A138 HydrophobicContact CE-CB 4.31Å; M88-L139 HydrophobicContact CB-CD1 4.12Å; M88-I142 HydrophobicContact CG-CD1 3.75Å; M88-W358 HydrophobicContact CB-CH2 4.47Å; M88-W358 HydrophobicContact CB-CZ2 4.45Å; M88-W358 HydrophobicContact CG-CD2 3.91Å; M88-W358 HydrophobicContact CG-CE3 4.11Å; M88-W358 HydrophobicContact CG-CH2 3.41Å; M88-W358 VanDerWaalsContact CG-CH2 3.41Å; M88-W358 HydrophobicContact CG-CZ2 3.14Å; M88-W358 HydrophobicContact CG-CZ3 3.88Å; M88-W358 HydrophobicContact SD-CD2 3.43Å; M88-W358 HydrophobicContact SD-CE3 3.85Å; M88-W358 HydrophobicContact SD-CG 3.9Å; M88-W358 HydrophobicContact SD-CH2 4.23Å; M88-W358 HydrophobicContact SD-CZ2 3.84Å; M88-W358 HydrophobicContact SD-CZ3 4.23Å; M88-Y361 HydrophobicContact CE-CD2 3.66Å; M88-Y361 HydrophobicContact CE-CE2 3.95Å; M88-Y361 HydrophobicContact SD-CD2 4.27Å
89	I	96.2	Very high	93.6	Very high	91 Å²	91	53.5 Å²	53.5	47%	0.467	29%	0.287	S	S	.	.	H	α-helix	trans	-60.4	-42.6	174.2	-70.3	164.5	0	0	0	110.2	S85 A86 L92 F93 L139	S85-I89 WeakPolarHBondContact O-CD1 3.42Å; S85-I89 VanDerWaalsContact O-CG1 3.23Å; S85-I89 WeakPolarHBondContact O-CG1 3.3Å; S85-I89 PolarHBondContact O-N 3.11Å; A86-I89 PolarHBondContact O-N 2.96Å; I89-L92 PolarHBondContact O-N 2.93Å; I89-F93 WeakPolarHBondContact O-CB 3.47Å; I89-F93 PolarHBondContact O-N 3.09Å; I89-L139 HydrophobicContact CD1-CD2 4.21Å; I89-L139 HydrophobicContact CG1-CD1 4.2Å; I89-L139 HydrophobicContact CG1-CD2 3.62Å
90	F	95.8	Very high	93.9	Very high	138 Å²	138	52 Å²	52	61%	0.605	27%	0.273	S	S	*	.	H	α-helix	trans	-62.7	-48.4	176.3	178.5	-99.6	0	0	0	112.2	A86 I87 M88 L92 F93 V94	A86-F90 PolarHBondContact O-N 3.43Å; I87-F90 WeakPolarHBondContact O-CB 3.34Å; I87-F90 PolarHBondContact O-N 2.96Å; M88-F90 VanDerWaalsContact C-N 3.29Å; M88-F90 PolarHBondContact O-N 3.22Å; F90-L92 VanDerWaalsContact C-N 3.33Å; F90-L92 PolarHBondContact O-N 3.4Å; F90-F93 PolarHBondContact O-N 3.13Å; F90-V94 HydrophobicContact CD1-CG2 4.4Å; F90-V94 HydrophobicContact CD2-CG2 4.31Å; F90-V94 HydrophobicContact CE1-CG2 4Å; F90-V94 HydrophobicContact CE2-CG2 3.89Å; F90-V94 HydrophobicContact CZ-CG2 3.73Å; F90-V94 WeakPolarHBondContact O-CG2 3.17Å; F90-V94 PolarHBondContact O-N 2.75Å
91	I	96	Very high	94.2	Very high	9 Å²	9	50.3 Å²	50.3	5%	0.046	27%	0.266	C	S	.	.	H	α-helix	trans	-59.3	-45.8	177.2	-68.5	170	0	0	0	110.6	I87 M88 F93 V94 S95 M135 W358 L362 A365	I87-I91 HydrophobicContact CG2-CD1 3.9Å; I87-I91 HydrophobicContact CG2-CG1 4.4Å; I87-I91 WeakPolarHBondContact O-CG1 3.49Å; I87-I91 PolarHBondContact O-N 3.46Å; M88-I91 PolarHBondContact O-N 3.38Å; I91-F93 PolarHBondContact O-N 2.87Å; I91-V94 PolarHBondContact O-N 3.28Å; I91-S95 WeakPolarHBondContact O-CB 3.36Å; I91-S95 PolarHBondContact O-N 3.44Å; I91-M135 HydrophobicContact CG2-SD 4.28Å; I91-W358 HydrophobicContact CD1-CE3 4.4Å; I91-L362 HydrophobicContact CD1-CD1 4.4Å; I91-L362 HydrophobicContact CG1-CD1 4.34Å; I91-A365 HydrophobicContact CG2-CB 4.25Å
92	L	96.4	Very high	94.5	Very high	43 Å²	43	48.9 Å²	48.9	23%	0.225	26%	0.26	C	S	.	.	H	α-helix	trans	-57.8	-50.2	177.3	-178.5	166.1	0	0	0	110.8	M88 I89 F90 S95 F96 M135 P136	M88-L92 VanDerWaalsContact O-CB 3.24Å; M88-L92 WeakPolarHBondContact O-CB 3.33Å; M88-L92 PolarHBondContact O-N 2.92Å; I89-L92 PolarHBondContact O-N 2.93Å; F90-L92 VanDerWaalsContact C-N 3.33Å; F90-L92 PolarHBondContact O-N 3.4Å; L92-S95 PolarHBondContact O-N 3.46Å; L92-F96 WeakPolarHBondContact O-CB 3.46Å; L92-F96 PolarHBondContact O-N 2.92Å; L92-M135 HydrophobicContact CB-CB 4.37Å; L92-M135 HydrophobicContact CB-SD 4.23Å; L92-M135 HydrophobicContact CD1-CB 4.08Å; L92-M135 HydrophobicContact CG-CB 4.24Å; L92-P136 HydrophobicContact CD1-CG 3.99Å
93	F	96.4	Very high	94.6	Very high	124 Å²	124	45.3 Å²	45.3	54%	0.544	24%	0.243	S	C	.	.	H	α-helix	trans	-62.1	-48.4	-178.1	-176.9	-98.2	0	0	0	112	I89 F90 I91 F96 L97	I89-F93 WeakPolarHBondContact O-CB 3.47Å; I89-F93 PolarHBondContact O-N 3.09Å; F90-F93 PolarHBondContact O-N 3.13Å; I91-F93 PolarHBondContact O-N 2.87Å; F93-F96 PolarHBondContact O-N 2.92Å; F93-L97 HydrophobicContact CE1-CD2 3.76Å; F93-L97 HydrophobicContact CE2-CD2 4.43Å; F93-L97 HydrophobicContact CZ-CD2 3.61Å; F93-L97 VanDerWaalsContact O-CB 3.29Å; F93-L97 WeakPolarHBondContact O-CB 3.43Å; F93-L97 PolarHBondContact O-N 3.37Å
94	V	96	Very high	94.7	Very high	26 Å²	26	44.6 Å²	44.6	16%	0.158	24%	0.236	C	C	.	.	H	α-helix	trans	-63.3	-43.7	178.1	175.1	0	0	0	0	110.8	F90 I91 G98 A365 L369	F90-V94 HydrophobicContact CD1-CG2 4.4Å; F90-V94 HydrophobicContact CD2-CG2 4.31Å; F90-V94 HydrophobicContact CE1-CG2 4Å; F90-V94 HydrophobicContact CE2-CG2 3.89Å; F90-V94 HydrophobicContact CZ-CG2 3.73Å; F90-V94 WeakPolarHBondContact O-CG2 3.17Å; F90-V94 PolarHBondContact O-N 2.75Å; I91-V94 PolarHBondContact O-N 3.28Å; V94-G98 WeakPolarHBondContact O-CA 3.41Å; V94-G98 PolarHBondContact O-N 3.3Å; V94-A365 HydrophobicContact CB-CB 4.17Å; V94-A365 HydrophobicContact CG1-CB 3.89Å; V94-L369 HydrophobicContact CG1-CD1 4.33Å; V94-L369 HydrophobicContact CG1-CG 4.45Å
95	S	96.8	Very high	94.6	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-62.2	-47.9	178.1	-175.5	0	0	0	0	111.5	I91 L92 N99 S364	I91-S95 WeakPolarHBondContact O-CB 3.36Å; I91-S95 PolarHBondContact O-N 3.44Å; L92-S95 PolarHBondContact O-N 3.46Å; S95-N99 VanDerWaalsContact O-CB 3.24Å; S95-N99 WeakPolarHBondContact O-CB 3.45Å; S95-N99 PolarHBondContact O-N 3.23Å; S95-N99 PolarHBondContact O-ND2 2.9Å; S95-S364 WeakPolarHBondContact OG-CB 3.07Å; S95-S364 PolarHBondContact OG-OG 3.24Å
96	F	97.3	Very high	94.5	Very high	77 Å²	77	44 Å²	44	34%	0.338	23%	0.233	S	C	.	.	H	α-helix	trans	-66.5	-56.7	-179.9	176.7	-103.4	0	0	0	111.6	L92 F93 N99 L100 M128 A131 V132	L92-F96 WeakPolarHBondContact O-CB 3.46Å; L92-F96 PolarHBondContact O-N 2.92Å; F93-F96 PolarHBondContact O-N 2.92Å; F96-N99 PolarHBondContact O-N 3.38Å; F96-L100 HydrophobicContact CE1-CD2 4.23Å; F96-L100 HydrophobicContact CZ-CD2 4.34Å; F96-L100 VanDerWaalsContact O-CB 3.24Å; F96-L100 WeakPolarHBondContact O-CB 3.45Å; F96-L100 PolarHBondContact O-N 2.99Å; F96-M128 HydrophobicContact CD2-CG 3.67Å; F96-M128 HydrophobicContact CD2-SD 4.46Å; F96-M128 HydrophobicContact CE2-CG 3.85Å; F96-M128 HydrophobicContact CE2-SD 4.1Å; F96-A131 HydrophobicContact CB-CB 4.34Å; F96-V132 HydrophobicContact CD2-CG2 3.63Å; F96-V132 HydrophobicContact CE2-CG2 3.77Å
97	L	95.4	Very high	94.2	Very high	75 Å²	75	49.9 Å²	49.9	39%	0.393	24%	0.244	S	C	.	.	H	α-helix	trans	-67.5	-42.7	-173.6	-175.6	61.5	0	0	0	111.8	F93 L100 V101	F93-L97 HydrophobicContact CE1-CD2 3.76Å; F93-L97 HydrophobicContact CE2-CD2 4.43Å; F93-L97 HydrophobicContact CZ-CD2 3.61Å; F93-L97 VanDerWaalsContact O-CB 3.29Å; F93-L97 WeakPolarHBondContact O-CB 3.43Å; F93-L97 PolarHBondContact O-N 3.37Å; L97-L100 PolarHBondContact O-N 3.19Å; L97-V101 WeakPolarHBondContact O-CG2 3.31Å; L97-V101 PolarHBondContact O-N 3.39Å
98	G	94.4	Very high	93.9	Very high	17 Å²	17	51.5 Å²	51.5	18%	0.175	25%	0.251	C	S	.	.	H	α-helix	trans	-62.1	-46.5	179.5	0	0	0	0	0	111.9	V94 V101 V102	V94-G98 WeakPolarHBondContact O-CA 3.41Å; V94-G98 PolarHBondContact O-N 3.3Å; G98-V101 PolarHBondContact O-N 2.94Å; G98-V102 WeakPolarHBondContact O-CG2 3.36Å; G98-V102 PolarHBondContact O-N 3.39Å; G98-V102 VanDerWaalsContact O-N 3.13Å
99	N	96.4	Very high	93.4	Very high	0 Å²	0	55.3 Å²	55.3	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-73	-30.9	179.4	-72.4	-62	0	0	0	112.6	S95 F96 V102 C103 A124 M128 S364 P368	S95-N99 VanDerWaalsContact O-CB 3.24Å; S95-N99 WeakPolarHBondContact O-CB 3.45Å; S95-N99 PolarHBondContact O-N 3.23Å; S95-N99 PolarHBondContact O-ND2 2.9Å; F96-N99 PolarHBondContact O-N 3.38Å; N99-V102 WeakPolarHBondContact O-CB 3.23Å; N99-V102 PolarHBondContact O-N 3.09Å; N99-C103 PolarHBondContact O-N 3.24Å; N99-C103 PolarHBondContact O-SG 3.26Å; N99-A124 HydrophobicContact CB-CB 3.97Å; N99-A124 WeakPolarHBondContact CB-O 3.22Å; N99-A124 WeakPolarHBondContact OD1-CA 3.3Å; N99-M128 HydrophobicContact CB-CB 4.17Å; N99-S364 PolarHBondContact ND2-O 2.7Å; N99-P368 HydrophobicContact CB-CG 4.32Å; N99-P368 VanDerWaalsContact CG-CG 3.5Å; N99-P368 VanDerWaalsContact OD1-CG 3.28Å; N99-P368 WeakPolarHBondContact OD1-CG 3.49Å
100	L	95.4	Very high	92.8	Very high	55 Å²	55	54.4 Å²	54.4	29%	0.288	27%	0.273	S	S	.	.	H	α-helix	trans	-59.9	-46.4	170.1	177.3	62.8	0	0	0	111.1	F96 L97 V102 C103 L104 M128	F96-L100 HydrophobicContact CE1-CD2 4.23Å; F96-L100 HydrophobicContact CZ-CD2 4.34Å; F96-L100 VanDerWaalsContact O-CB 3.24Å; F96-L100 WeakPolarHBondContact O-CB 3.45Å; F96-L100 PolarHBondContact O-N 2.99Å; L97-L100 PolarHBondContact O-N 3.19Å; L100-V102 PolarHBondContact O-N 2.98Å; L100-C103 PolarHBondContact O-N 3.44Å; L100-L104 HydrophobicContact CD1-CD1 4.21Å; L100-L104 HydrophobicContact CD1-CG 4.17Å; L100-L104 HydrophobicContact CG-CD1 4.02Å; L100-L104 HydrophobicContact CG-CG 4.39Å; L100-L104 WeakPolarHBondContact O-CG 3.48Å; L100-L104 PolarHBondContact O-N 3.48Å; L100-M128 HydrophobicContact CB-SD 4.32Å; L100-M128 HydrophobicContact CD1-SD 4.17Å
101	V	92.6	Very high	92	Very high	35 Å²	35	52.6 Å²	52.6	21%	0.212	28%	0.284	C	S	.	.	H	α-helix	trans	-59.3	-45.2	176.3	168.6	0	0	0	0	110.9	L97 G98 C103 L104 M105	L97-V101 WeakPolarHBondContact O-CG2 3.31Å; L97-V101 PolarHBondContact O-N 3.39Å; G98-V101 PolarHBondContact O-N 2.94Å; V101-C103 VanDerWaalsContact C-N 3.32Å; V101-C103 PolarHBondContact O-N 3.13Å; V101-L104 PolarHBondContact O-N 2.95Å; V101-M105 HydrophobicContact CG1-CG 4.15Å; V101-M105 HydrophobicContact CG1-SD 3.5Å; V101-M105 VanDerWaalsContact CG1-SD 3.5Å; V101-M105 WeakPolarHBondContact O-CB 3.25Å; V101-M105 WeakPolarHBondContact O-CG 3.42Å; V101-M105 PolarHBondContact O-N 2.76Å
102	V	93	Very high	91.2	Very high	1 Å²	1	52.8 Å²	52.8	1%	0.006	29%	0.285	C	S	.	.	H	α-helix	trans	-54.4	-48.7	174.9	177	0	0	0	0	111.2	G98 N99 L100 M105 V106 A124 P368 Y371 F378	G98-V102 WeakPolarHBondContact O-CG2 3.36Å; G98-V102 PolarHBondContact O-N 3.39Å; G98-V102 VanDerWaalsContact O-N 3.13Å; N99-V102 WeakPolarHBondContact O-CB 3.23Å; N99-V102 PolarHBondContact O-N 3.09Å; L100-V102 PolarHBondContact O-N 2.98Å; V102-M105 PolarHBondContact O-N 2.88Å; V102-V106 WeakPolarHBondContact O-CG2 3.49Å; V102-V106 PolarHBondContact O-N 3.45Å; V102-A124 HydrophobicContact CB-CB 3.71Å; V102-A124 HydrophobicContact CG1-CB 3.58Å; V102-A124 HydrophobicContact CG2-CB 4.38Å; V102-P368 HydrophobicContact CG2-CB 4.25Å; V102-P368 HydrophobicContact CG2-CG 4.34Å; V102-Y371 HydrophobicContact CG2-CD2 3.87Å; V102-Y371 HydrophobicContact CG2-CE2 4.39Å; V102-F378 HydrophobicContact CB-CE2 4.09Å; V102-F378 HydrophobicContact CB-CZ 4.06Å; V102-F378 HydrophobicContact CG1-CE2 4.09Å; V102-F378 HydrophobicContact CG2-CE1 4.45Å; V102-F378 HydrophobicContact CG2-CE2 3.73Å; V102-F378 HydrophobicContact CG2-CZ 3.36Å
103	C	94.5	Very high	90.8	Very high	28 Å²	28	57 Å²	57	19%	0.189	30%	0.298	C	S	.	.	H	α-helix	trans	-62	-48.1	179.7	-66.2	0	0	0	0	111.8	N99 L100 V101 M105 V106 Y107	N99-C103 PolarHBondContact O-N 3.24Å; N99-C103 PolarHBondContact O-SG 3.26Å; L100-C103 PolarHBondContact O-N 3.44Å; V101-C103 VanDerWaalsContact C-N 3.32Å; V101-C103 PolarHBondContact O-N 3.13Å; C103-M105 PolarHBondContact O-N 2.86Å; C103-V106 PolarHBondContact O-N 3.47Å; C103-Y107 PolarHBondContact O-N 3.03Å; C103-Y107 VanDerWaalsContact O-N 3.07Å
104	L	91.4	Very high	90.5	Very high	62 Å²	62	53.7 Å²	53.7	33%	0.325	29%	0.289	S	S	.	.	H	α-helix	trans	-62.6	-41.3	-179.3	-69.6	175.3	0	0	0	112	L100 V101 V106 Y107 Q108 M385	L100-L104 HydrophobicContact CD1-CD1 4.21Å; L100-L104 HydrophobicContact CD1-CG 4.17Å; L100-L104 HydrophobicContact CG-CD1 4.02Å; L100-L104 HydrophobicContact CG-CG 4.39Å; L100-L104 WeakPolarHBondContact O-CG 3.48Å; L100-L104 PolarHBondContact O-N 3.48Å; V101-L104 PolarHBondContact O-N 2.95Å; L104-V106 VanDerWaalsContact C-N 3.34Å; L104-V106 PolarHBondContact O-N 3.11Å; L104-Y107 PolarHBondContact O-N 3.01Å; L104-Q108 VanDerWaalsContact O-CB 3.31Å; L104-Q108 WeakPolarHBondContact O-CB 3.45Å; L104-Q108 VanDerWaalsContact O-CG 3.3Å; L104-Q108 WeakPolarHBondContact O-CG 3.28Å; L104-Q108 PolarHBondContact O-N 3.05Å; L104-M385 HydrophobicContact CB-CE 3.68Å; L104-M385 HydrophobicContact CD1-CE 4.34Å
105	M	87.9	Confident	90.3	Very high	0 Å²	0	52.9 Å²	52.9	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-60.2	-42.9	179.6	-73.4	167.1	71.9	0	0	112.4	V101 V102 C103 K109 F378 A381 C382 M385	V101-M105 HydrophobicContact CG1-CG 4.15Å; V101-M105 HydrophobicContact CG1-SD 3.5Å; V101-M105 VanDerWaalsContact CG1-SD 3.5Å; V101-M105 WeakPolarHBondContact O-CB 3.25Å; V101-M105 WeakPolarHBondContact O-CG 3.42Å; V101-M105 PolarHBondContact O-N 2.76Å; V102-M105 PolarHBondContact O-N 2.88Å; C103-M105 PolarHBondContact O-N 2.86Å; M105-K109 WeakPolarHBondContact O-CB 3.34Å; M105-K109 PolarHBondContact O-N 3.3Å; M105-F378 HydrophobicContact CE-CB 4.17Å; M105-F378 HydrophobicContact CE-CD1 3.84Å; M105-F378 HydrophobicContact CE-CD2 3.49Å; M105-F378 VanDerWaalsContact CE-CD2 3.49Å; M105-F378 HydrophobicContact CE-CE1 3.98Å; M105-F378 HydrophobicContact CE-CE2 3.63Å; M105-F378 HydrophobicContact CE-CG 3.58Å; M105-F378 HydrophobicContact CE-CZ 3.85Å; M105-F378 WeakPolarHBondContact CE-O 3.38Å; M105-F378 HydrophobicContact SD-CD1 4.24Å; M105-F378 HydrophobicContact SD-CD2 4.04Å; M105-F378 HydrophobicContact SD-CE1 3.76Å; M105-F378 HydrophobicContact SD-CE2 3.5Å; M105-F378 VanDerWaalsContact SD-CE2 3.5Å; M105-F378 HydrophobicContact SD-CG 4.36Å; M105-F378 HydrophobicContact SD-CZ 3.32Å; M105-F378 WeakPolarHBondContact SD-CZ 3.07Å; M105-A381 HydrophobicContact CE-CB 3.42Å; M105-A381 VanDerWaalsContact CE-CB 3.42Å; M105-C382 HydrophobicContact CE-CB 4.43Å; M105-C382 HydrophobicContact SD-CB 4.4Å; M105-M385 HydrophobicContact CB-SD 4.39Å; M105-M385 HydrophobicContact CG-SD 3.38Å; M105-M385 WeakPolarHBondContact CG-SD 3.4Å
106	V	90.4	Very high	90	Very high	14 Å²	14	54.3 Å²	54.3	9%	0.085	29%	0.293	C	S	.	.	H	α-helix	trans	-71.9	-37.4	179.1	178.4	0	0	0	0	111.2	V102 C103 L104 R113 N117 I118 A121	V102-V106 WeakPolarHBondContact O-CG2 3.49Å; V102-V106 PolarHBondContact O-N 3.45Å; C103-V106 PolarHBondContact O-N 3.47Å; L104-V106 VanDerWaalsContact C-N 3.34Å; L104-V106 PolarHBondContact O-N 3.11Å; V106-R113 WeakPolarHBondContact O-CG 3.29Å; V106-N117 HydrophobicContact CG1-CB 4.45Å; V106-N117 HydrophobicContact CG2-CB 4.09Å; V106-I118 HydrophobicContact CG1-CG1 4.39Å; V106-A121 HydrophobicContact CB-CB 4.07Å; V106-A121 HydrophobicContact CG1-CB 4.12Å; V106-A121 HydrophobicContact CG2-CB 4.13Å
107	Y	88.1	Confident	89.7	Confident	178 Å²	178	52 Å²	52	70%	0.698	28%	0.284	S	S	*	.	H	α-helix	trans	-69.1	-47.3	178.3	-175.3	-99.7	0	0	0	112.4	C103 L104 R113	C103-Y107 PolarHBondContact O-N 3.03Å; C103-Y107 VanDerWaalsContact O-N 3.07Å; L104-Y107 PolarHBondContact O-N 3.01Å; Y107-R113 PolarHBondContact O-NE 2.83Å; Y107-R113 PolarHBondContact O-NH2 3.48Å
108	Q	87.1	Confident	89.7	Confident	107 Å²	107	49.8 Å²	49.8	50%	0.5	27%	0.272	S	S	.	.	H	α-helix	trans	-78.1	-35.2	-172.3	-67.9	-178.9	-3.1	0	0	113.5	L104	L104-Q108 VanDerWaalsContact O-CB 3.31Å; L104-Q108 WeakPolarHBondContact O-CB 3.45Å; L104-Q108 VanDerWaalsContact O-CG 3.3Å; L104-Q108 WeakPolarHBondContact O-CG 3.28Å; L104-Q108 PolarHBondContact O-N 3.05Å
109	K	83.7	Confident	89.7	Confident	81 Å²	81	49 Å²	49	35%	0.352	26%	0.264	S	S	.	.			trans	-100.6	108.4	-174	-58	-68.7	-175.1	172.5	0	110.7	M105 A111 M112	M105-K109 WeakPolarHBondContact O-CB 3.34Å; M105-K109 PolarHBondContact O-N 3.3Å; K109-A111 PolarHBondContact O-N 3.42Å; K109-M112 HydrophobicContact CB-CB 4.14Å; K109-M112 HydrophobicContact CB-CG 3.93Å; K109-M112 WeakPolarHBondContact O-CB 3.46Å; K109-M112 PolarHBondContact O-N 2.96Å
110	A	83.4	Confident	89.6	Confident	72 Å²	72	49.8 Å²	49.8	60%	0.595	27%	0.268	S	S	*	.	G	3₁₀ helix	trans	-54.9	-36.9	176.7	0	0	0	0	0	112.9	M112 R113	A110-M112 PolarHBondContact O-N 3.45Å; A110-M112 VanDerWaalsContact O-N 3.11Å; A110-R113 WeakPolarHBondContact O-CB 3.43Å; A110-R113 PolarHBondContact O-N 3.38Å; A110-R113 VanDerWaalsContact O-N 3.1Å
111	A	78.3	Confident	89.6	Confident	100 Å²	100	48 Å²	48	83%	0.826	26%	0.262	S	S	*	.	G	3₁₀ helix	trans	-62.3	-16.4	176.1	0	0	0	0	0	114.3	K109	K109-A111 PolarHBondContact O-N 3.42Å
112	M	80.8	Confident	89.8	Confident	14 Å²	14	46.8 Å²	46.8	7%	0.069	26%	0.255	C	S	.	.	G	3₁₀ helix	trans	-99.8	1	178.8	-66.3	-66.1	-78.1	0	0	112.9	K109 A110 S114 N117 K377	K109-M112 HydrophobicContact CB-CB 4.14Å; K109-M112 HydrophobicContact CB-CG 3.93Å; K109-M112 WeakPolarHBondContact O-CB 3.46Å; K109-M112 PolarHBondContact O-N 2.96Å; A110-M112 PolarHBondContact O-N 3.45Å; A110-M112 VanDerWaalsContact O-N 3.11Å; M112-S114 PolarHBondContact O-N 3.37Å; M112-N117 WeakPolarHBondContact O-CB 3.28Å; M112-N117 PolarHBondContact O-ND2 2.96Å; M112-K377 HydrophobicContact SD-CB 4.26Å
113	R	86.6	Confident	89.9	Confident	132 Å²	132	46.8 Å²	46.8	50%	0.498	26%	0.255	S	S	.	.			trans	-82.2	42.6	-178.3	-62.3	179.4	-177.2	166.1	-1.9	113.6	V106 Y107 A110	V106-R113 WeakPolarHBondContact O-CG 3.29Å; Y107-R113 PolarHBondContact O-NE 2.83Å; Y107-R113 PolarHBondContact O-NH2 3.48Å; A110-R113 WeakPolarHBondContact O-CB 3.43Å; A110-R113 PolarHBondContact O-N 3.38Å; A110-R113 VanDerWaalsContact O-N 3.1Å
114	S	90.5	Very high	90.1	Very high	53 Å²	53	45.4 Å²	45.4	37%	0.371	25%	0.246	S	C	.	.			trans	-74.8	157.6	171.2	74.5	0	0	0	0	110.7	M112 I116 N117 I118	M112-S114 PolarHBondContact O-N 3.37Å; S114-I116 PolarHBondContact O-N 3.06Å; S114-N117 PolarHBondContact O-N 3.26Å; S114-N117 WeakPolarHBondContact OG-CB 3.16Å; S114-N117 PolarHBondContact OG-N 2.89Å; S114-N117 PolarHBondContact OG-ND2 2.77Å; S114-I118 WeakPolarHBondContact O-CG1 3.33Å; S114-I118 PolarHBondContact O-N 3.15Å
115	A	92	Very high	90.4	Very high	10 Å²	10	46.7 Å²	46.7	8%	0.083	25%	0.249	C	C	.	.	H	α-helix	trans	-54.4	-41.1	179.7	0	0	0	0	0	112.6	I118 L119 L190 P192 A195	A115-I118 PolarHBondContact O-N 3.41Å; A115-L119 WeakPolarHBondContact O-CG 3.42Å; A115-L119 PolarHBondContact O-N 3.08Å; A115-L119 VanDerWaalsContact O-N 3.09Å; A115-L190 HydrophobicContact CB-CD2 4.08Å; A115-L190 HydrophobicContact CB-CG 3.9Å; A115-P192 HydrophobicContact CB-CG 4.46Å; A115-A195 HydrophobicContact CB-CB 4.05Å
116	I	90.1	Very high	90.9	Very high	30 Å²	30	46.7 Å²	46.7	15%	0.154	25%	0.249	C	C	.	.	H	α-helix	trans	-72.1	-40.5	-178.6	-61	179.4	0	0	0	111.5	S114 I118 L119 L120 R179 L190	S114-I116 PolarHBondContact O-N 3.06Å; I116-I118 PolarHBondContact O-N 3.47Å; I116-L119 WeakPolarHBondContact O-CB 3.43Å; I116-L119 PolarHBondContact O-N 3.18Å; I116-L119 VanDerWaalsContact O-N 3.17Å; I116-L120 HydrophobicContact CG2-CD1 4.38Å; I116-L120 HydrophobicContact CG2-CG 4.47Å; I116-L120 WeakPolarHBondContact O-CG 3.3Å; I116-L120 PolarHBondContact O-N 3.21Å; I116-R179 VanDerWaalsContact CD1-NH1 3.3Å; I116-L190 HydrophobicContact CG1-CD2 4.39Å
117	N	91.6	Very high	91.2	Very high	28 Å²	28	46.2 Å²	46.2	15%	0.15	25%	0.245	C	C	.	.	H	α-helix	trans	-66.6	-31.4	176.5	-70.7	-4.8	0	0	0	111.5	V106 M112 S114 L120 A121	V106-N117 HydrophobicContact CG1-CB 4.45Å; V106-N117 HydrophobicContact CG2-CB 4.09Å; M112-N117 WeakPolarHBondContact O-CB 3.28Å; M112-N117 PolarHBondContact O-ND2 2.96Å; S114-N117 PolarHBondContact O-N 3.26Å; S114-N117 WeakPolarHBondContact OG-CB 3.16Å; S114-N117 PolarHBondContact OG-N 2.89Å; S114-N117 PolarHBondContact OG-ND2 2.77Å; N117-L120 PolarHBondContact O-N 2.82Å; N117-A121 WeakPolarHBondContact O-CB 3.41Å; N117-A121 PolarHBondContact O-N 3.09Å
118	I	94.9	Very high	91.6	Very high	28 Å²	28	39 Å²	39	14%	0.144	22%	0.219	C	C	.	.	H	α-helix	trans	-65.5	-42.2	171.6	-67.2	165.1	0	0	0	110.7	V106 S114 A115 I116 A121 S122 P192 K196 I199	V106-I118 HydrophobicContact CG1-CG1 4.39Å; S114-I118 WeakPolarHBondContact O-CG1 3.33Å; S114-I118 PolarHBondContact O-N 3.15Å; A115-I118 PolarHBondContact O-N 3.41Å; I116-I118 PolarHBondContact O-N 3.47Å; I118-A121 PolarHBondContact O-N 2.89Å; I118-S122 PolarHBondContact O-N 3.2Å; I118-P192 HydrophobicContact CD1-CB 3.8Å; I118-K196 HydrophobicContact CG2-CG 4.32Å; I118-I199 HydrophobicContact CG2-CD1 3.65Å
119	L	95.6	Very high	92.2	Very high	0 Å²	0	35.9 Å²	35.9	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-61.4	-46.8	172.8	-69.4	170.8	0	0	0	111.5	A115 I116 A121 S122 L123 I171 I174 I175 L190 A195 I199	A115-L119 WeakPolarHBondContact O-CG 3.42Å; A115-L119 PolarHBondContact O-N 3.08Å; A115-L119 VanDerWaalsContact O-N 3.09Å; I116-L119 WeakPolarHBondContact O-CB 3.43Å; I116-L119 PolarHBondContact O-N 3.18Å; I116-L119 VanDerWaalsContact O-N 3.17Å; L119-A121 VanDerWaalsContact C-N 3.25Å; L119-A121 PolarHBondContact O-N 3.2Å; L119-S122 WeakPolarHBondContact O-CB 2.98Å; L119-S122 PolarHBondContact O-N 3.28Å; L119-L123 PolarHBondContact O-N 3.02Å; L119-I171 HydrophobicContact CB-CG2 4.03Å; L119-I171 HydrophobicContact CD2-CD1 3.89Å; L119-I171 WeakPolarHBondContact O-CG2 3.46Å; L119-I174 HydrophobicContact CD1-CG2 3.69Å; L119-I174 HydrophobicContact CD2-CG2 4.04Å; L119-I175 HydrophobicContact CB-CD1 4.16Å; L119-I175 HydrophobicContact CB-CG1 4.09Å; L119-I175 HydrophobicContact CD1-CG1 3.93Å; L119-L190 HydrophobicContact CD1-CD2 3.79Å; L119-A195 HydrophobicContact CD2-CB 4.46Å; L119-A195 HydrophobicContact CG-CB 4.29Å; L119-I199 HydrophobicContact CD2-CD1 4.02Å; L119-I199 HydrophobicContact CD2-CG1 3.8Å
120	L	93.3	Very high	92.8	Very high	17 Å²	17	32.3 Å²	32.3	9%	0.089	19%	0.19	C	C	.	.	H	α-helix	trans	-60.1	-35.2	175.9	-67	176.2	0	0	0	112.3	I116 N117 L123 A124 I175 Y371 I375	I116-L120 HydrophobicContact CG2-CD1 4.38Å; I116-L120 HydrophobicContact CG2-CG 4.47Å; I116-L120 WeakPolarHBondContact O-CG 3.3Å; I116-L120 PolarHBondContact O-N 3.21Å; N117-L120 PolarHBondContact O-N 2.82Å; L120-L123 PolarHBondContact O-N 2.89Å; L120-A124 WeakPolarHBondContact O-CB 3.27Å; L120-A124 PolarHBondContact O-N 3Å; L120-I175 HydrophobicContact CD2-CD1 3.78Å; L120-I175 HydrophobicContact CG-CD1 4.41Å; L120-Y371 HydrophobicContact CD2-CE1 3.79Å; L120-I375 HydrophobicContact CD1-CD1 4.4Å
121	A	95.3	Very high	93.4	Very high	18 Å²	18	28.9 Å²	28.9	15%	0.149	16%	0.162	C	C	.	.	H	α-helix	trans	-67.9	-37.5	173.1	0	0	0	0	0	112.5	V106 N117 I118 L119 A124 F125	V106-A121 HydrophobicContact CB-CB 4.07Å; V106-A121 HydrophobicContact CG1-CB 4.12Å; V106-A121 HydrophobicContact CG2-CB 4.13Å; N117-A121 WeakPolarHBondContact O-CB 3.41Å; N117-A121 PolarHBondContact O-N 3.09Å; I118-A121 PolarHBondContact O-N 2.89Å; L119-A121 VanDerWaalsContact C-N 3.25Å; L119-A121 PolarHBondContact O-N 3.2Å; A121-A124 PolarHBondContact O-N 2.81Å; A121-F125 WeakPolarHBondContact O-CB 3.42Å; A121-F125 PolarHBondContact O-N 3.38Å
122	S	97.4	Very high	94.3	Very high	10 Å²	10	27.4 Å²	27.4	7%	0.07	14%	0.142	C	C	.	.	H	α-helix	trans	-62.3	-45.4	172.8	-163.4	0	0	0	0	111.4	I118 L119 A124 F125 A126 E167 I199 W203	I118-S122 PolarHBondContact O-N 3.2Å; L119-S122 WeakPolarHBondContact O-CB 2.98Å; L119-S122 PolarHBondContact O-N 3.28Å; S122-A124 PolarHBondContact O-N 3.28Å; S122-F125 PolarHBondContact O-N 3.24Å; S122-A126 PolarHBondContact O-N 2.84Å; S122-E167 PolarHBondContact OG-OE1 3.45Å; S122-I199 WeakPolarHBondContact OG-CG2 3.33Å; S122-W203 PolarHBondContact OG-NE1 3.48Å
123	L	96.1	Very high	95	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-59	-46.6	175.4	177	60.1	0	0	0	111.5	L119 L120 F125 A126 D127 G168 I171 L172 Y371	L119-L123 PolarHBondContact O-N 3.02Å; L120-L123 PolarHBondContact O-N 2.89Å; L123-F125 VanDerWaalsContact C-N 3.33Å; L123-F125 PolarHBondContact O-N 2.69Å; L123-A126 PolarHBondContact O-N 2.65Å; L123-D127 WeakPolarHBondContact O-CB 3.14Å; L123-D127 PolarHBondContact O-N 3.42Å; L123-G168 VanDerWaalsContact CD1-CA 3.43Å; L123-I171 HydrophobicContact CB-CB 4.37Å; L123-I171 HydrophobicContact CB-CG2 3.89Å; L123-L172 HydrophobicContact CD2-CD2 3.96Å; L123-L172 HydrophobicContact CD2-CG 4.29Å; L123-Y371 VanDerWaalsContact CD2-OH 3.26Å; L123-Y371 WeakPolarHBondContact CD2-OH 3.33Å
124	A	96.9	Very high	95.4	Very high	0 Å²	0	23 Å²	23	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-63.3	-38.2	176.4	0	0	0	0	0	112.3	N99 V102 L120 A121 S122 D127 M128	N99-A124 HydrophobicContact CB-CB 3.97Å; N99-A124 WeakPolarHBondContact CB-O 3.22Å; N99-A124 WeakPolarHBondContact OD1-CA 3.3Å; V102-A124 HydrophobicContact CB-CB 3.71Å; V102-A124 HydrophobicContact CG1-CB 3.58Å; V102-A124 HydrophobicContact CG2-CB 4.38Å; L120-A124 WeakPolarHBondContact O-CB 3.27Å; L120-A124 PolarHBondContact O-N 3Å; A121-A124 PolarHBondContact O-N 2.81Å; S122-A124 PolarHBondContact O-N 3.28Å; A124-D127 PolarHBondContact O-N 3.5Å; A124-M128 VanDerWaalsContact O-CB 3.3Å; A124-M128 WeakPolarHBondContact O-CB 3.35Å; A124-M128 PolarHBondContact O-N 2.99Å
125	F	98	Very high	95.6	Very high	89 Å²	89	20.4 Å²	20.4	39%	0.39	11%	0.111	S	C	.	.	H	α-helix	trans	-63.8	-43.1	176.5	-176.4	-112.4	0	0	0	111.8	A121 S122 L123 M128 L129 W203	A121-F125 WeakPolarHBondContact O-CB 3.42Å; A121-F125 PolarHBondContact O-N 3.38Å; S122-F125 PolarHBondContact O-N 3.24Å; L123-F125 VanDerWaalsContact C-N 3.33Å; L123-F125 PolarHBondContact O-N 2.69Å; F125-M128 HydrophobicContact CD2-CE 3.63Å; F125-M128 HydrophobicContact CE2-CE 3.74Å; F125-M128 PolarHBondContact O-N 3.32Å; F125-L129 HydrophobicContact CD1-CD1 4.02Å; F125-L129 HydrophobicContact CE1-CD1 3.53Å; F125-L129 HydrophobicContact CE1-CG 4.36Å; F125-L129 HydrophobicContact CE2-CD1 4.39Å; F125-L129 HydrophobicContact CE2-CG 4.42Å; F125-L129 HydrophobicContact CZ-CD1 3.74Å; F125-L129 HydrophobicContact CZ-CD2 4.44Å; F125-L129 HydrophobicContact CZ-CG 4.22Å; F125-L129 WeakPolarHBondContact O-CG 3.33Å; F125-L129 PolarHBondContact O-N 3.29Å; F125-W203 HydrophobicContact CD1-CH2 4.2Å; F125-W203 AromaticContact CD1-CZ2 3.76Å; F125-W203 HydrophobicContact CD1-CZ2 3.76Å; F125-W203 HydrophobicContact CE1-CH2 4.37Å; F125-W203 HydrophobicContact CE1-CZ2 4.23Å
126	A	98	Very high	95.7	Very high	0 Å²	0	22 Å²	22	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-63.3	-44.9	174.4	0	0	0	0	0	112.4	S122 L123 M128 L129 L130 F164 E167 W203	S122-A126 PolarHBondContact O-N 2.84Å; L123-A126 PolarHBondContact O-N 2.65Å; A126-M128 VanDerWaalsContact C-N 3.33Å; A126-M128 PolarHBondContact O-N 3.17Å; A126-L129 PolarHBondContact O-N 3.4Å; A126-L130 WeakPolarHBondContact O-CB 3.43Å; A126-L130 PolarHBondContact O-N 3.01Å; A126-F164 HydrophobicContact CB-CB 4.33Å; A126-F164 HydrophobicContact CB-CD1 4.35Å; A126-E167 HydrophobicContact CB-CB 4.44Å; A126-E167 HydrophobicContact CB-CG 3.93Å; A126-W203 HydrophobicContact CB-CH2 4.22Å; A126-W203 HydrophobicContact CB-CZ2 4.17Å
127	D	97.6	Very high	95.8	Very high	3 Å²	3	22.8 Å²	22.8	2%	0.016	12%	0.122	C	C	.	.	H	α-helix	trans	-64.1	-35.7	177	-83.1	-17.4	0	0	0	112	L123 A124 A131 K363 S364 N367	L123-D127 WeakPolarHBondContact O-CB 3.14Å; L123-D127 PolarHBondContact O-N 3.42Å; A124-D127 PolarHBondContact O-N 3.5Å; D127-A131 WeakPolarHBondContact O-CB 3.37Å; D127-A131 PolarHBondContact O-N 2.96Å; D127-K363 IonicContact OD1-NZ 3.44Å; D127-K363 PolarHBondContact OD1-NZ 2.9Å; D127-K363 IonicContact OD2-NZ 3.05Å; D127-K363 PolarHBondContact OD2-NZ 3.44Å; D127-S364 WeakPolarHBondContact CB-OG 3.3Å; D127-S364 PolarHBondContact O-OG 3.34Å; D127-N367 PolarHBondContact OD2-ND2 2.86Å
128	M	97.4	Very high	95.8	Very high	28 Å²	28	21.5 Å²	21.5	14%	0.138	12%	0.116	C	C	.	.	H	α-helix	trans	-65.8	-45.5	172.4	-175.6	-173.6	72.9	0	0	111.5	F96 N99 L100 A124 F125 A126 L130 A131 V132	F96-M128 HydrophobicContact CD2-CG 3.67Å; F96-M128 HydrophobicContact CD2-SD 4.46Å; F96-M128 HydrophobicContact CE2-CG 3.85Å; F96-M128 HydrophobicContact CE2-SD 4.1Å; N99-M128 HydrophobicContact CB-CB 4.17Å; L100-M128 HydrophobicContact CB-SD 4.32Å; L100-M128 HydrophobicContact CD1-SD 4.17Å; A124-M128 VanDerWaalsContact O-CB 3.3Å; A124-M128 WeakPolarHBondContact O-CB 3.35Å; A124-M128 PolarHBondContact O-N 2.99Å; F125-M128 HydrophobicContact CD2-CE 3.63Å; F125-M128 HydrophobicContact CE2-CE 3.74Å; F125-M128 PolarHBondContact O-N 3.32Å; A126-M128 VanDerWaalsContact C-N 3.33Å; A126-M128 PolarHBondContact O-N 3.17Å; M128-L130 VanDerWaalsContact C-N 3.34Å; M128-A131 WeakPolarHBondContact O-CB 3.43Å; M128-A131 PolarHBondContact O-N 3.25Å; M128-V132 WeakPolarHBondContact O-CG2 3.46Å; M128-V132 PolarHBondContact O-N 2.98Å; M128-V132 VanDerWaalsContact O-N 3.08Å
129	L	97.9	Very high	95.7	Very high	41 Å²	41	21.4 Å²	21.4	22%	0.215	12%	0.115	C	C	.	.	H	α-helix	trans	-64.8	-38	176.9	-71.2	176.4	0	0	0	111.8	F125 A126 A131 V132 L133 F164 W203	F125-L129 HydrophobicContact CD1-CD1 4.02Å; F125-L129 HydrophobicContact CE1-CD1 3.53Å; F125-L129 HydrophobicContact CE1-CG 4.36Å; F125-L129 HydrophobicContact CE2-CD1 4.39Å; F125-L129 HydrophobicContact CE2-CG 4.42Å; F125-L129 HydrophobicContact CZ-CD1 3.74Å; F125-L129 HydrophobicContact CZ-CD2 4.44Å; F125-L129 HydrophobicContact CZ-CG 4.22Å; F125-L129 WeakPolarHBondContact O-CG 3.33Å; F125-L129 PolarHBondContact O-N 3.29Å; A126-L129 PolarHBondContact O-N 3.4Å; L129-A131 VanDerWaalsContact C-N 3.31Å; L129-A131 PolarHBondContact O-N 2.9Å; L129-V132 PolarHBondContact O-N 3.24Å; L129-L133 HydrophobicContact CB-CD1 4.38Å; L129-L133 HydrophobicContact CD2-CD1 4.39Å; L129-L133 VanDerWaalsContact O-CB 3.28Å; L129-L133 WeakPolarHBondContact O-CB 3.42Å; L129-L133 WeakPolarHBondContact O-CG 3.35Å; L129-L133 PolarHBondContact O-N 3.32Å; L129-F164 HydrophobicContact CB-CD1 4.04Å; L129-F164 HydrophobicContact CB-CD2 4.2Å; L129-F164 HydrophobicContact CB-CE1 3.59Å; L129-F164 HydrophobicContact CB-CE2 3.76Å; L129-F164 HydrophobicContact CB-CG 4.36Å; L129-F164 HydrophobicContact CB-CZ 3.46Å; L129-F164 VanDerWaalsContact CB-CZ 3.46Å; L129-F164 HydrophobicContact CD1-CD1 4.32Å; L129-F164 HydrophobicContact CD1-CE1 3.52Å; L129-F164 HydrophobicContact CD1-CZ 3.92Å; L129-F164 HydrophobicContact CG-CE1 4.22Å; L129-F164 HydrophobicContact CG-CZ 4.28Å; L129-W203 HydrophobicContact CD1-CH2 4.04Å
130	L	96.8	Very high	95.5	Very high	5 Å²	5	23.6 Å²	23.6	3%	0.026	13%	0.128	C	C	.	.	H	α-helix	trans	-59.7	-41.9	171.8	-177.8	67.3	0	0	0	111.5	A126 M128 V132 N134 M135 F161 F164 Y361	A126-L130 WeakPolarHBondContact O-CB 3.43Å; A126-L130 PolarHBondContact O-N 3.01Å; M128-L130 VanDerWaalsContact C-N 3.34Å; L130-V132 VanDerWaalsContact C-N 3.29Å; L130-V132 PolarHBondContact O-N 3.4Å; L130-N134 HydrophobicContact CD1-CB 3.97Å; L130-N134 WeakPolarHBondContact O-CB 3.35Å; L130-N134 PolarHBondContact O-N 3.33Å; L130-N134 VanDerWaalsContact O-N 3.13Å; L130-M135 PolarHBondContact O-N 2.84Å; L130-F161 HydrophobicContact CD1-CD2 3.92Å; L130-F161 HydrophobicContact CD1-CE2 4.49Å; L130-F164 HydrophobicContact CB-CB 4.15Å; L130-F164 HydrophobicContact CB-CD2 4.03Å; L130-F164 HydrophobicContact CB-CG 4.4Å; L130-F164 HydrophobicContact CD1-CD2 4.34Å; L130-Y361 HydrophobicContact CD1-CE1 4.3Å; L130-Y361 HydrophobicContact CD2-CD1 4.37Å; L130-Y361 HydrophobicContact CG-CE1 4.47Å
131	A	97.1	Very high	95.3	Very high	1 Å²	1	23 Å²	23	1%	0.008	13%	0.125	C	C	.	.	H	α-helix	trans	-65.8	-29.7	177.5	0	0	0	0	0	113.5	F96 D127 M128 L129 M135 P136	F96-A131 HydrophobicContact CB-CB 4.34Å; D127-A131 WeakPolarHBondContact O-CB 3.37Å; D127-A131 PolarHBondContact O-N 2.96Å; M128-A131 WeakPolarHBondContact O-CB 3.43Å; M128-A131 PolarHBondContact O-N 3.25Å; L129-A131 VanDerWaalsContact C-N 3.31Å; L129-A131 PolarHBondContact O-N 2.9Å; A131-M135 HydrophobicContact CB-CE 4.11Å; A131-M135 HydrophobicContact CB-SD 3.94Å; A131-P136 VanDerWaalsContact O-CD 3.29Å; A131-P136 WeakPolarHBondContact O-CD 3.38Å
132	V	96.8	Very high	94.9	Very high	68 Å²	68	23 Å²	23	41%	0.412	12%	0.122	S	C	.	.	H	α-helix	trans	-89.8	-40.8	-179.6	174	0	0	0	0	112	F96 M128 L129 L130 P136	F96-V132 HydrophobicContact CD2-CG2 3.63Å; F96-V132 HydrophobicContact CE2-CG2 3.77Å; M128-V132 WeakPolarHBondContact O-CG2 3.46Å; M128-V132 PolarHBondContact O-N 2.98Å; M128-V132 VanDerWaalsContact O-N 3.08Å; L129-V132 PolarHBondContact O-N 3.24Å; L130-V132 VanDerWaalsContact C-N 3.29Å; L130-V132 PolarHBondContact O-N 3.4Å; V132-P136 WeakPolarHBondContact O-CD 3.37Å; V132-P136 WeakPolarHBondContact O-CG 3.33Å
133	L	96	Very high	94.4	Very high	51 Å²	51	26.8 Å²	26.8	27%	0.267	14%	0.142	S	C	.	.	H	α-helix	trans	-93.1	-13.6	-169.6	-62.3	175.2	0	0	0	113.7	L129 F137 F160 F164	L129-L133 HydrophobicContact CB-CD1 4.38Å; L129-L133 HydrophobicContact CD2-CD1 4.39Å; L129-L133 VanDerWaalsContact O-CB 3.28Å; L129-L133 WeakPolarHBondContact O-CB 3.42Å; L129-L133 WeakPolarHBondContact O-CG 3.35Å; L129-L133 PolarHBondContact O-N 3.32Å; L133-F137 WeakPolarHBondContact O-CD2 3.45Å; L133-F137 VanDerWaalsContact O-CE2 3.24Å; L133-F137 WeakPolarHBondContact O-CE2 3.39Å; L133-F160 HydrophobicContact CD1-CD1 4.16Å; L133-F160 HydrophobicContact CD1-CD2 4.43Å; L133-F160 HydrophobicContact CD1-CE1 4.3Å; L133-F160 HydrophobicContact CD1-CG 4.25Å; L133-F160 HydrophobicContact CD1-CZ 4.49Å; L133-F164 HydrophobicContact CB-CE2 4.28Å; L133-F164 HydrophobicContact CD1-CE2 3.71Å; L133-F164 HydrophobicContact CD1-CZ 3.62Å
134	N	94	Very high	94	Very high	2 Å²	2	29.1 Å²	29.1	1%	0.011	16%	0.156	C	C	.	.	T	Hydrogen-bonded Turn	trans	-127.6	-49.4	-176.1	-69.3	42.6	0	0	0	113.5	L130 P136 F137 A138 S157 F161	L130-N134 HydrophobicContact CD1-CB 3.97Å; L130-N134 WeakPolarHBondContact O-CB 3.35Å; L130-N134 PolarHBondContact O-N 3.33Å; L130-N134 VanDerWaalsContact O-N 3.13Å; N134-P136 VanDerWaalsContact C-CD 3.43Å; N134-F137 PolarHBondContact O-N 3.18Å; N134-A138 PolarHBondContact O-N 3.29Å; N134-S157 PolarHBondContact ND2-O 3Å; N134-S157 VanDerWaalsContact ND2-O 3.16Å; N134-F161 WeakPolarHBondContact ND2-CA 3.35Å; N134-F161 WeakPolarHBondContact ND2-CB 3.33Å; N134-F161 PolarHBondContact ND2-N 3.44Å
135	M	95.2	Very high	93.3	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-58.8	-37.6	-174.9	-60.9	-174.6	-168.5	0	0	114.7	I91 L92 L130 A131 F137 A138 L139 Y361	I91-M135 HydrophobicContact CG2-SD 4.28Å; L92-M135 HydrophobicContact CB-CB 4.37Å; L92-M135 HydrophobicContact CB-SD 4.23Å; L92-M135 HydrophobicContact CD1-CB 4.08Å; L92-M135 HydrophobicContact CG-CB 4.24Å; L130-M135 PolarHBondContact O-N 2.84Å; A131-M135 HydrophobicContact CB-CE 4.11Å; A131-M135 HydrophobicContact CB-SD 3.94Å; M135-F137 VanDerWaalsContact C-N 3.35Å; M135-F137 PolarHBondContact O-N 2.85Å; M135-A138 PolarHBondContact O-N 3.41Å; M135-L139 WeakPolarHBondContact O-CB 3.32Å; M135-L139 PolarHBondContact O-N 2.92Å; M135-Y361 HydrophobicContact CE-CD1 3.91Å; M135-Y361 HydrophobicContact CE-CG 4.06Å; M135-Y361 HydrophobicContact CG-CD1 4.06Å; M135-Y361 HydrophobicContact CG-CD2 4.35Å; M135-Y361 HydrophobicContact CG-CE1 4.24Å; M135-Y361 HydrophobicContact CG-CE2 4.5Å; M135-Y361 HydrophobicContact CG-CG 4.11Å
136	P	94.6	Very high	92.6	Very high	42 Å²	42	36 Å²	36	27%	0.273	19%	0.187	S	C	.	.	H	α-helix	trans	-67.1	-37	178.4	-19.1	32.2	0	0	0	112.1	L92 A131 V132 N134 L139 V140	L92-P136 HydrophobicContact CD1-CG 3.99Å; A131-P136 VanDerWaalsContact O-CD 3.29Å; A131-P136 WeakPolarHBondContact O-CD 3.38Å; V132-P136 WeakPolarHBondContact O-CD 3.37Å; V132-P136 WeakPolarHBondContact O-CG 3.33Å; N134-P136 VanDerWaalsContact C-CD 3.43Å; P136-L139 WeakPolarHBondContact O-CB 3.48Å; P136-L139 PolarHBondContact O-N 2.9Å; P136-V140 WeakPolarHBondContact O-CG2 3.45Å; P136-V140 PolarHBondContact O-N 3.12Å
137	F	92.3	Very high	92.1	Very high	48 Å²	48	37.1 Å²	37.1	21%	0.211	19%	0.191	C	C	.	.	H	α-helix	trans	-72.6	-34.9	178.6	-55	-78.8	0	0	0	111.4	L133 N134 M135 V140 T141 W147 F149 F153	L133-F137 WeakPolarHBondContact O-CD2 3.45Å; L133-F137 VanDerWaalsContact O-CE2 3.24Å; L133-F137 WeakPolarHBondContact O-CE2 3.39Å; N134-F137 PolarHBondContact O-N 3.18Å; M135-F137 VanDerWaalsContact C-N 3.35Å; M135-F137 PolarHBondContact O-N 2.85Å; F137-V140 PolarHBondContact O-N 2.98Å; F137-T141 WeakPolarHBondContact O-CB 3.33Å; F137-T141 PolarHBondContact O-N 3.14Å; F137-T141 PolarHBondContact O-OG1 2.96Å; F137-W147 HydrophobicContact CB-CH2 4.12Å; F137-W147 HydrophobicContact CB-CZ3 4.18Å; F137-F149 HydrophobicContact CB-CD2 4.42Å; F137-F149 HydrophobicContact CB-CE2 3.96Å; F137-F149 HydrophobicContact CB-CZ 4.42Å; F137-F149 HydrophobicContact CD1-CD1 4.07Å; F137-F149 HydrophobicContact CD1-CD2 4.15Å; F137-F149 AromaticContact CD1-CE1 3.7Å; F137-F149 HydrophobicContact CD1-CE1 3.7Å; F137-F149 AromaticContact CD1-CE2 3.79Å; F137-F149 HydrophobicContact CD1-CE2 3.79Å; F137-F149 HydrophobicContact CD1-CG 4.29Å; F137-F149 AromaticContact CD1-CZ 3.55Å; F137-F149 HydrophobicContact CD1-CZ 3.55Å; F137-F149 HydrophobicContact CE1-CD1 4.4Å; F137-F149 HydrophobicContact CE1-CE1 4.09Å; F137-F149 HydrophobicContact CE1-CZ 4.34Å; F137-F149 HydrophobicContact CG-CE2 4.39Å; F137-F149 HydrophobicContact CG-CZ 4.46Å; F137-F153 HydrophobicContact CB-CE1 4.34Å; F137-F153 HydrophobicContact CD1-CD1 4.34Å; F137-F153 AromaticContact CD1-CE1 3.34Å; F137-F153 HydrophobicContact CD1-CE1 3.34Å; F137-F153 AromaticContact CD1-CZ 3.84Å; F137-F153 HydrophobicContact CD1-CZ 3.84Å; F137-F153 AromaticContact CD2-CE1 3.96Å; F137-F153 HydrophobicContact CD2-CE1 3.96Å; F137-F153 AromaticContact CD2-CZ 3.99Å; F137-F153 HydrophobicContact CD2-CZ 3.99Å; F137-F153 AromaticContact CE1-CE1 3.47Å; F137-F153 HydrophobicContact CE1-CE1 3.47Å; F137-F153 VanDerWaalsContact CE1-CE1 3.47Å; F137-F153 AromaticContact CE1-CZ 3.49Å; F137-F153 HydrophobicContact CE1-CZ 3.49Å; F137-F153 VanDerWaalsContact CE1-CZ 3.49Å; F137-F153 HydrophobicContact CE2-CE1 4.07Å; F137-F153 AromaticContact CE2-CZ 3.66Å; F137-F153 HydrophobicContact CE2-CZ 3.66Å; F137-F153 AromaticContact CG-CE1 3.6Å; F137-F153 HydrophobicContact CG-CE1 3.6Å; F137-F153 HydrophobicContact CG-CZ 4.08Å; F137-F153 AromaticContact CZ-CE1 3.84Å; F137-F153 HydrophobicContact CZ-CE1 3.84Å; F137-F153 HydrophobicContact CZ-CE2 4.42Å; F137-F153 AromaticContact CZ-CZ 3.4Å; F137-F153 HydrophobicContact CZ-CZ 3.4Å
138	A	90.8	Very high	91.7	Very high	1 Å²	1	41.1 Å²	41.1	1%	0.008	21%	0.212	C	C	.	.	H	α-helix	trans	-61.9	-43.1	168.5	0	0	0	0	0	111.7	M88 N134 M135 T141 I142 P227 Y361	M88-A138 HydrophobicContact CE-CB 4.31Å; N134-A138 PolarHBondContact O-N 3.29Å; M135-A138 PolarHBondContact O-N 3.41Å; A138-T141 PolarHBondContact O-N 3.28Å; A138-I142 WeakPolarHBondContact O-CD1 3.49Å; A138-I142 WeakPolarHBondContact O-CG1 3.37Å; A138-I142 PolarHBondContact O-N 3.49Å; A138-P227 WeakPolarHBondContact CA-O 3.37Å; A138-P227 HydrophobicContact CB-CB 4.23Å; A138-Y361 HydrophobicContact CB-CE2 3.92Å
139	L	92.7	Very high	91.3	Very high	25 Å²	25	42.9 Å²	42.9	13%	0.131	22%	0.219	C	C	.	.	H	α-helix	trans	-60.3	-48	174.9	176	64.8	0	0	0	112	M88 I89 M135 P136 T141 I142 L143	M88-L139 HydrophobicContact CB-CD1 4.12Å; I89-L139 HydrophobicContact CD1-CD2 4.21Å; I89-L139 HydrophobicContact CG1-CD1 4.2Å; I89-L139 HydrophobicContact CG1-CD2 3.62Å; M135-L139 WeakPolarHBondContact O-CB 3.32Å; M135-L139 PolarHBondContact O-N 2.92Å; P136-L139 WeakPolarHBondContact O-CB 3.48Å; P136-L139 PolarHBondContact O-N 2.9Å; L139-T141 PolarHBondContact O-N 3.03Å; L139-I142 WeakPolarHBondContact O-CB 3.39Å; L139-I142 PolarHBondContact O-N 2.92Å; L139-I142 VanDerWaalsContact O-N 3.13Å; L139-L143 HydrophobicContact CG-CD1 4.36Å; L139-L143 WeakPolarHBondContact O-CG 3.37Å; L139-L143 PolarHBondContact O-N 2.73Å
140	V	91.9	Very high	90.9	Very high	46 Å²	46	42.7 Å²	42.7	28%	0.279	23%	0.227	S	C	.	.	H	α-helix	trans	-61	-37	176.7	173.2	0	0	0	0	111.2	P136 F137 I142 L143 T144 I148 F149	P136-V140 WeakPolarHBondContact O-CG2 3.45Å; P136-V140 PolarHBondContact O-N 3.12Å; F137-V140 PolarHBondContact O-N 2.98Å; V140-I142 VanDerWaalsContact C-N 3.34Å; V140-L143 PolarHBondContact O-N 3.43Å; V140-T144 HydrophobicContact CG1-CG2 4.07Å; V140-T144 WeakPolarHBondContact O-CB 3.39Å; V140-T144 WeakPolarHBondContact O-CG2 3.05Å; V140-T144 PolarHBondContact O-N 3.43Å; V140-T144 PolarHBondContact O-OG1 3.42Å; V140-I148 HydrophobicContact CG1-CD1 4.04Å; V140-I148 HydrophobicContact CG1-CG1 4.32Å; V140-F149 HydrophobicContact CB-CE2 4.02Å; V140-F149 HydrophobicContact CB-CZ 3.71Å; V140-F149 HydrophobicContact CG1-CE2 3.93Å; V140-F149 HydrophobicContact CG1-CZ 3.55Å; V140-F149 HydrophobicContact CG2-CZ 4.11Å
141	T	88	Confident	90.5	Very high	5 Å²	5	47 Å²	47	3%	0.031	25%	0.245	C	C	.	.	H	α-helix	trans	-68.9	-33.1	177.5	-54.4	0	0	0	0	112.1	F137 A138 L139 T145 W147 A226	F137-T141 WeakPolarHBondContact O-CB 3.33Å; F137-T141 PolarHBondContact O-N 3.14Å; F137-T141 PolarHBondContact O-OG1 2.96Å; A138-T141 PolarHBondContact O-N 3.28Å; L139-T141 PolarHBondContact O-N 3.03Å; T141-T145 WeakPolarHBondContact O-CA 3.4Å; T141-T145 PolarHBondContact O-N 3.47Å; T141-W147 VanDerWaalsContact OG1-CE3 3.32Å; T141-A226 VanDerWaalsContact CG2-O 3.26Å; T141-A226 WeakPolarHBondContact CG2-O 3.4Å
142	I	86.4	Confident	90.1	Very high	17 Å²	17	54.2 Å²	54.2	9%	0.087	28%	0.277	C	S	.	.	H	α-helix	trans	-64.9	-42.5	170.2	-67.9	155.6	0	0	0	110.8	Q81 L84 M88 A138 L139 V140 W358	Q81-I142 PolarHBondContact NE2-O 3.33Å; L84-I142 HydrophobicContact CB-CG2 4.4Å; M88-I142 HydrophobicContact CG-CD1 3.75Å; A138-I142 WeakPolarHBondContact O-CD1 3.49Å; A138-I142 WeakPolarHBondContact O-CG1 3.37Å; A138-I142 PolarHBondContact O-N 3.49Å; L139-I142 WeakPolarHBondContact O-CB 3.39Å; L139-I142 PolarHBondContact O-N 2.92Å; L139-I142 VanDerWaalsContact O-N 3.13Å; V140-I142 VanDerWaalsContact C-N 3.34Å; I142-W358 HydrophobicContact CD1-CZ2 3.57Å
143	L	88.2	Confident	89.9	Confident	91 Å²	91	53.6 Å²	53.6	48%	0.476	27%	0.268	S	S	.	.	H	α-helix	trans	-69.3	-40.1	-180	-68.6	173	0	0	0	112.9	Q81 S85 L139 V140	Q81-L143 VanDerWaalsContact NE2-C 3.31Å; Q81-L143 PolarHBondContact NE2-O 3.28Å; S85-L143 VanDerWaalsContact OG-CD2 3.3Å; S85-L143 WeakPolarHBondContact OG-CD2 3.4Å; L139-L143 HydrophobicContact CG-CD1 4.36Å; L139-L143 WeakPolarHBondContact O-CG 3.37Å; L139-L143 PolarHBondContact O-N 2.73Å; V140-L143 PolarHBondContact O-N 3.43Å
144	T	86.9	Confident	89.6	Confident	48 Å²	48	51.1 Å²	51.1	29%	0.294	26%	0.256	S	S	.	.	H	α-helix	trans	-93	-9.2	-176.2	57	0	0	0	0	113.1	V140 R146 I148	V140-T144 HydrophobicContact CG1-CG2 4.07Å; V140-T144 WeakPolarHBondContact O-CB 3.39Å; V140-T144 WeakPolarHBondContact O-CG2 3.05Å; V140-T144 PolarHBondContact O-N 3.43Å; V140-T144 PolarHBondContact O-OG1 3.42Å; T144-R146 PolarHBondContact O-N 2.85Å; T144-R146 PolarHBondContact OG1-O 3.35Å; T144-I148 HydrophobicContact CG2-CD1 4.26Å
145	T	82.9	Confident	89.5	Confident	67 Å²	67	53.3 Å²	53.3	41%	0.411	26%	0.263	S	S	.	.	S	Bend	trans	59.3	5.6	-175	67.8	0	0	0	0	115.3	T141	T141-T145 WeakPolarHBondContact O-CA 3.4Å; T141-T145 PolarHBondContact O-N 3.47Å
146	R	83	Confident	89.4	Confident	167 Å²	167	54.5 Å²	54.5	63%	0.63	27%	0.271	S	S	*	.	S	Bend	trans	-148	148.7	-178.1	69	-174.2	-178.6	172.4	-0.8	110.6	T144 I148	T144-R146 PolarHBondContact O-N 2.85Å; T144-R146 PolarHBondContact OG1-O 3.35Å; R146-I148 HydrophobicContact CG-CG2 3.69Å; R146-I148 PolarHBondContact O-N 3.26Å
147	W	87.1	Confident	89.4	Confident	24 Å²	24	52.6 Å²	52.6	9%	0.091	26%	0.259	C	S	.	.			trans	-75.8	109.2	174.3	-178.1	-91.7	0	0	0	110.9	F137 T141 F149 G150 F153 C154 I222	F137-W147 HydrophobicContact CB-CH2 4.12Å; F137-W147 HydrophobicContact CB-CZ3 4.18Å; T141-W147 VanDerWaalsContact OG1-CE3 3.32Å; W147-F149 HydrophobicContact CD2-CD2 4.07Å; W147-F149 AromaticContact CE2-CD2 3.94Å; W147-F149 HydrophobicContact CE3-CD2 4.16Å; W147-F149 HydrophobicContact CH2-CD2 4.05Å; W147-F149 HydrophobicContact CZ2-CB 3.93Å; W147-F149 AromaticContact CZ2-CD2 3.96Å; W147-F149 HydrophobicContact CZ2-CD2 3.96Å; W147-F149 HydrophobicContact CZ2-CG 4.36Å; W147-F149 HydrophobicContact CZ3-CD2 4.14Å; W147-G150 PolarHBondContact NE1-O 2.76Å; W147-F153 HydrophobicContact CH2-CD1 4.1Å; W147-F153 HydrophobicContact CH2-CE1 4.26Å; W147-F153 AromaticContact CZ2-CD1 3.63Å; W147-F153 HydrophobicContact CZ2-CD1 3.63Å; W147-F153 HydrophobicContact CZ2-CE1 4.25Å; W147-C154 HydrophobicContact CZ2-CB 4.17Å; W147-I222 HydrophobicContact CB-CG2 3.82Å; W147-I222 HydrophobicContact CG-CG2 4.22Å
148	I	89.2	Confident	89.4	Confident	87 Å²	87	50.5 Å²	50.5	45%	0.446	25%	0.25	S	C	.	.			trans	-96.8	-6.5	-176	61.4	166.4	0	0	0	114.9	V140 T144 R146 G150	V140-I148 HydrophobicContact CG1-CD1 4.04Å; V140-I148 HydrophobicContact CG1-CG1 4.32Å; T144-I148 HydrophobicContact CG2-CD1 4.26Å; R146-I148 HydrophobicContact CG-CG2 3.69Å; R146-I148 PolarHBondContact O-N 3.26Å; I148-G150 VanDerWaalsContact C-N 3.26Å; I148-G150 PolarHBondContact O-N 3.04Å
149	F	89.9	Confident	89.6	Confident	65 Å²	65	50.8 Å²	50.8	29%	0.285	25%	0.251	S	S	.	.	S	Bend	trans	-83.5	3.2	-172.4	-55.3	-77	0	0	0	114.3	F137 V140 W147 F153	F137-F149 HydrophobicContact CB-CD2 4.42Å; F137-F149 HydrophobicContact CB-CE2 3.96Å; F137-F149 HydrophobicContact CB-CZ 4.42Å; F137-F149 HydrophobicContact CD1-CD1 4.07Å; F137-F149 HydrophobicContact CD1-CD2 4.15Å; F137-F149 AromaticContact CD1-CE1 3.7Å; F137-F149 HydrophobicContact CD1-CE1 3.7Å; F137-F149 AromaticContact CD1-CE2 3.79Å; F137-F149 HydrophobicContact CD1-CE2 3.79Å; F137-F149 HydrophobicContact CD1-CG 4.29Å; F137-F149 AromaticContact CD1-CZ 3.55Å; F137-F149 HydrophobicContact CD1-CZ 3.55Å; F137-F149 HydrophobicContact CE1-CD1 4.4Å; F137-F149 HydrophobicContact CE1-CE1 4.09Å; F137-F149 HydrophobicContact CE1-CZ 4.34Å; F137-F149 HydrophobicContact CG-CE2 4.39Å; F137-F149 HydrophobicContact CG-CZ 4.46Å; V140-F149 HydrophobicContact CB-CE2 4.02Å; V140-F149 HydrophobicContact CB-CZ 3.71Å; V140-F149 HydrophobicContact CG1-CE2 3.93Å; V140-F149 HydrophobicContact CG1-CZ 3.55Å; V140-F149 HydrophobicContact CG2-CZ 4.11Å; W147-F149 HydrophobicContact CD2-CD2 4.07Å; W147-F149 AromaticContact CE2-CD2 3.94Å; W147-F149 HydrophobicContact CE3-CD2 4.16Å; W147-F149 HydrophobicContact CH2-CD2 4.05Å; W147-F149 HydrophobicContact CZ2-CB 3.93Å; W147-F149 AromaticContact CZ2-CD2 3.96Å; W147-F149 HydrophobicContact CZ2-CD2 3.96Å; W147-F149 HydrophobicContact CZ2-CG 4.36Å; W147-F149 HydrophobicContact CZ3-CD2 4.14Å; F149-F153 HydrophobicContact CB-CB 3.98Å; F149-F153 HydrophobicContact CB-CD1 3.47Å; F149-F153 VanDerWaalsContact CB-CD1 3.47Å; F149-F153 HydrophobicContact CB-CE1 4.39Å; F149-F153 HydrophobicContact CB-CG 4.06Å; F149-F153 HydrophobicContact CD1-CD1 4.46Å; F149-F153 HydrophobicContact CD2-CD1 4.46Å; F149-F153 AromaticContact CG-CD1 3.91Å; F149-F153 HydrophobicContact CG-CD1 3.91Å; F149-F153 HydrophobicContact CG-CE1 4.38Å; F149-F153 WeakPolarHBondContact O-CB 3.21Å
150	G	88.9	Confident	89.8	Confident	37 Å²	37	52.6 Å²	52.6	38%	0.381	26%	0.258	S	S	.	.	H	α-helix	trans	78.1	172.5	179.9	0	0	0	0	0	114.8	W147 I148 C154	W147-G150 PolarHBondContact NE1-O 2.76Å; I148-G150 VanDerWaalsContact C-N 3.26Å; I148-G150 PolarHBondContact O-N 3.04Å; G150-C154 WeakPolarHBondContact O-CB 3.35Å; G150-C154 PolarHBondContact O-N 3.49Å; G150-C154 VanDerWaalsContact O-N 3.16Å
151	K	87.7	Confident	90	Very high	95 Å²	95	50.5 Å²	50.5	41%	0.413	25%	0.245	S	C	.	.	H	α-helix	trans	-70.4	-35.7	-174.1	-168.3	-179.5	-177	-170.5	0	113.4	C154 R155 D219 I222	K151-C154 WeakPolarHBondContact O-CB 3.05Å; K151-R155 VanDerWaalsContact NZ-NH2 3.11Å; K151-R155 WeakPolarHBondContact O-CG 3.1Å; K151-R155 PolarHBondContact O-N 3.23Å; K151-D219 IonicContact NZ-OD1 2.92Å; K151-D219 PolarHBondContact NZ-OD1 3.48Å; K151-I222 HydrophobicContact CB-CD1 4.05Å; K151-I222 HydrophobicContact CG-CD1 4.34Å
152	F	90.1	Very high	90.4	Very high	153 Å²	153	50.7 Å²	50.7	67%	0.671	25%	0.245	S	C	*	.	H	α-helix	trans	-64	-52.2	178.2	178	-100	0	0	0	111.3	C154 R155 V156	F152-C154 VanDerWaalsContact C-N 3.29Å; F152-C154 PolarHBondContact O-N 3.25Å; F152-R155 WeakPolarHBondContact O-CB 3.42Å; F152-R155 PolarHBondContact O-N 2.88Å; F152-R155 VanDerWaalsContact O-N 3.16Å; F152-V156 HydrophobicContact CD1-CG2 4.4Å; F152-V156 HydrophobicContact CE1-CG2 3.94Å; F152-V156 HydrophobicContact CE2-CG2 4.27Å; F152-V156 HydrophobicContact CZ-CG2 3.87Å; F152-V156 PolarHBondContact O-N 3.46Å; F152-V156 VanDerWaalsContact O-N 3.12Å
153	F	91.3	Very high	90.9	Very high	54 Å²	54	50.3 Å²	50.3	24%	0.237	24%	0.243	C	C	.	.	H	α-helix	trans	-66.8	-32	-179.7	-166.5	-105.7	0	0	0	112.5	F137 W147 F149 R155 V156 S157	F137-F153 HydrophobicContact CB-CE1 4.34Å; F137-F153 HydrophobicContact CD1-CD1 4.34Å; F137-F153 AromaticContact CD1-CE1 3.34Å; F137-F153 HydrophobicContact CD1-CE1 3.34Å; F137-F153 AromaticContact CD1-CZ 3.84Å; F137-F153 HydrophobicContact CD1-CZ 3.84Å; F137-F153 AromaticContact CD2-CE1 3.96Å; F137-F153 HydrophobicContact CD2-CE1 3.96Å; F137-F153 AromaticContact CD2-CZ 3.99Å; F137-F153 HydrophobicContact CD2-CZ 3.99Å; F137-F153 AromaticContact CE1-CE1 3.47Å; F137-F153 HydrophobicContact CE1-CE1 3.47Å; F137-F153 VanDerWaalsContact CE1-CE1 3.47Å; F137-F153 AromaticContact CE1-CZ 3.49Å; F137-F153 HydrophobicContact CE1-CZ 3.49Å; F137-F153 VanDerWaalsContact CE1-CZ 3.49Å; F137-F153 HydrophobicContact CE2-CE1 4.07Å; F137-F153 AromaticContact CE2-CZ 3.66Å; F137-F153 HydrophobicContact CE2-CZ 3.66Å; F137-F153 AromaticContact CG-CE1 3.6Å; F137-F153 HydrophobicContact CG-CE1 3.6Å; F137-F153 HydrophobicContact CG-CZ 4.08Å; F137-F153 AromaticContact CZ-CE1 3.84Å; F137-F153 HydrophobicContact CZ-CE1 3.84Å; F137-F153 HydrophobicContact CZ-CE2 4.42Å; F137-F153 AromaticContact CZ-CZ 3.4Å; F137-F153 HydrophobicContact CZ-CZ 3.4Å; W147-F153 HydrophobicContact CH2-CD1 4.1Å; W147-F153 HydrophobicContact CH2-CE1 4.26Å; W147-F153 AromaticContact CZ2-CD1 3.63Å; W147-F153 HydrophobicContact CZ2-CD1 3.63Å; W147-F153 HydrophobicContact CZ2-CE1 4.25Å; F149-F153 HydrophobicContact CB-CB 3.98Å; F149-F153 HydrophobicContact CB-CD1 3.47Å; F149-F153 VanDerWaalsContact CB-CD1 3.47Å; F149-F153 HydrophobicContact CB-CE1 4.39Å; F149-F153 HydrophobicContact CB-CG 4.06Å; F149-F153 HydrophobicContact CD1-CD1 4.46Å; F149-F153 HydrophobicContact CD2-CD1 4.46Å; F149-F153 AromaticContact CG-CD1 3.91Å; F149-F153 HydrophobicContact CG-CD1 3.91Å; F149-F153 HydrophobicContact CG-CE1 4.38Å; F149-F153 WeakPolarHBondContact O-CB 3.21Å; F153-R155 PolarHBondContact O-N 2.95Å; F153-V156 PolarHBondContact O-N 3.31Å; F153-S157 WeakPolarHBondContact O-CB 3.34Å; F153-S157 PolarHBondContact O-N 3.4Å
154	C	90.6	Very high	91.3	Very high	0 Å²	0	46.2 Å²	46.2	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-53.2	-49.6	170	163.4	0	0	0	0	112.6	W147 G150 K151 F152 A158 I222 C229	W147-C154 HydrophobicContact CZ2-CB 4.17Å; G150-C154 WeakPolarHBondContact O-CB 3.35Å; G150-C154 PolarHBondContact O-N 3.49Å; G150-C154 VanDerWaalsContact O-N 3.16Å; K151-C154 WeakPolarHBondContact O-CB 3.05Å; F152-C154 VanDerWaalsContact C-N 3.29Å; F152-C154 PolarHBondContact O-N 3.25Å; C154-A158 WeakPolarHBondContact O-CB 3.44Å; C154-A158 PolarHBondContact O-N 3.3Å; C154-I222 HydrophobicContact CB-CG1 4.39Å; C154-C229 WeakPolarHBondContact CA-SG 3.41Å; C154-C229 HydrophobicContact CB-CB 4.22Å; C154-C229 WeakPolarHBondContact CB-SG 3.46Å; C154-C229 WeakPolarHBondContact SG-CB 3.32Å; C154-C229 CovalentContact SG-SG 1.99Å; C154-C229 PolarHBondContact SG-SG 2.84Å
155	R	91.5	Very high	91.8	Very high	47 Å²	47	44.2 Å²	44.2	18%	0.177	21%	0.21	C	C	.	.	H	α-helix	trans	-63.3	-46.4	178.4	-75.2	172.9	-179.6	178.7	-3.6	112.2	K151 F152 F153 A158 M159 L213 D219 L220	K151-R155 VanDerWaalsContact NZ-NH2 3.11Å; K151-R155 WeakPolarHBondContact O-CG 3.1Å; K151-R155 PolarHBondContact O-N 3.23Å; F152-R155 WeakPolarHBondContact O-CB 3.42Å; F152-R155 PolarHBondContact O-N 2.88Å; F152-R155 VanDerWaalsContact O-N 3.16Å; F153-R155 PolarHBondContact O-N 2.95Å; R155-A158 PolarHBondContact O-N 2.87Å; R155-M159 WeakPolarHBondContact O-CB 3.45Å; R155-M159 PolarHBondContact O-N 3.21Å; R155-L213 VanDerWaalsContact CB-O 3.29Å; R155-L213 WeakPolarHBondContact CB-O 3.32Å; R155-D219 IonicContact CZ-OD1 3.67Å; R155-D219 IonicContact NE-OD1 3.92Å; R155-D219 IonicContact NH2-OD1 2.69Å; R155-D219 PolarHBondContact NH2-OD1 3.05Å; R155-L220 HydrophobicContact CG-CD1 4.47Å
156	V	93.4	Very high	92.4	Very high	26 Å²	26	41.3 Å²	41.3	16%	0.158	19%	0.192	C	C	.	.	H	α-helix	trans	-65.8	-41.9	179.2	174.2	0	0	0	0	111.5	F152 F153 M159 F160	F152-V156 HydrophobicContact CD1-CG2 4.4Å; F152-V156 HydrophobicContact CE1-CG2 3.94Å; F152-V156 HydrophobicContact CE2-CG2 4.27Å; F152-V156 HydrophobicContact CZ-CG2 3.87Å; F152-V156 PolarHBondContact O-N 3.46Å; F152-V156 VanDerWaalsContact O-N 3.12Å; F153-V156 PolarHBondContact O-N 3.31Å; V156-M159 WeakPolarHBondContact O-CB 3.36Å; V156-M159 PolarHBondContact O-N 3.47Å; V156-F160 HydrophobicContact CG1-CD2 3.74Å; V156-F160 HydrophobicContact CG1-CE2 3.45Å; V156-F160 VanDerWaalsContact CG1-CE2 3.45Å; V156-F160 HydrophobicContact CG1-CZ 4.4Å; V156-F160 WeakPolarHBondContact O-CD2 3.31Å; V156-F160 PolarHBondContact O-N 2.91Å
157	S	93.7	Very high	93.1	Very high	2 Å²	2	33.4 Å²	33.4	1%	0.014	16%	0.162	C	C	.	.	H	α-helix	trans	-65.2	-39.5	177.1	-177.4	0	0	0	0	112	N134 F153 F160 F161	N134-S157 PolarHBondContact ND2-O 3Å; N134-S157 VanDerWaalsContact ND2-O 3.16Å; F153-S157 WeakPolarHBondContact O-CB 3.34Å; F153-S157 PolarHBondContact O-N 3.4Å; S157-F160 PolarHBondContact O-N 3.03Å; S157-F161 WeakPolarHBondContact O-CB 3.3Å; S157-F161 PolarHBondContact O-N 2.83Å
158	A	93.3	Very high	93.6	Very high	3 Å²	3	32.3 Å²	32.3	3%	0.025	16%	0.158	C	C	.	.	H	α-helix	trans	-65.3	-38.9	172.4	0	0	0	0	0	112.2	C154 R155 F161 W162 L220 C229	C154-A158 WeakPolarHBondContact O-CB 3.44Å; C154-A158 PolarHBondContact O-N 3.3Å; R155-A158 PolarHBondContact O-N 2.87Å; A158-F161 WeakPolarHBondContact O-CB 3.32Å; A158-F161 PolarHBondContact O-N 3.41Å; A158-W162 PolarHBondContact O-N 2.89Å; A158-W162 VanDerWaalsContact O-N 3.07Å; A158-L220 HydrophobicContact CB-CD1 3.49Å; A158-L220 VanDerWaalsContact CB-CD1 3.49Å; A158-C229 HydrophobicContact CB-CB 4.27Å
159	M	95.7	Very high	93.9	Very high	8 Å²	8	28.3 Å²	28.3	4%	0.039	14%	0.137	C	C	.	.	H	α-helix	trans	-60.7	-48.8	173.3	-178	-111.2	104.9	0	0	111	R155 V156 F161 W162 L163 F207 A210 L213 A214	R155-M159 WeakPolarHBondContact O-CB 3.45Å; R155-M159 PolarHBondContact O-N 3.21Å; V156-M159 WeakPolarHBondContact O-CB 3.36Å; V156-M159 PolarHBondContact O-N 3.47Å; M159-F161 VanDerWaalsContact C-N 3.33Å; M159-F161 PolarHBondContact O-N 3.43Å; M159-W162 PolarHBondContact O-N 3.22Å; M159-L163 HydrophobicContact CE-CB 3.59Å; M159-L163 HydrophobicContact CE-CD2 3.39Å; M159-L163 HydrophobicContact CE-CG 4.07Å; M159-L163 WeakPolarHBondContact O-CB 3.35Å; M159-L163 PolarHBondContact O-N 3.34Å; M159-F207 HydrophobicContact CE-CD2 4.36Å; M159-A210 HydrophobicContact CG-CB 4.18Å; M159-A210 WeakPolarHBondContact CG-O 3.35Å; M159-L213 HydrophobicContact CB-CB 3.97Å; M159-A214 HydrophobicContact CB-CB 4.1Å; M159-A214 HydrophobicContact CG-CB 3.99Å; M159-A214 HydrophobicContact SD-CB 4.26Å
160	F	96.6	Very high	94.2	Very high	63 Å²	63	26.3 Å²	26.3	28%	0.276	13%	0.133	S	C	.	.	H	α-helix	trans	-61.3	-40.1	176.3	-78.5	-49.5	0	0	0	112.7	L133 V156 S157 W162 L163 F164	L133-F160 HydrophobicContact CD1-CD1 4.16Å; L133-F160 HydrophobicContact CD1-CD2 4.43Å; L133-F160 HydrophobicContact CD1-CE1 4.3Å; L133-F160 HydrophobicContact CD1-CG 4.25Å; L133-F160 HydrophobicContact CD1-CZ 4.49Å; V156-F160 HydrophobicContact CG1-CD2 3.74Å; V156-F160 HydrophobicContact CG1-CE2 3.45Å; V156-F160 VanDerWaalsContact CG1-CE2 3.45Å; V156-F160 HydrophobicContact CG1-CZ 4.4Å; V156-F160 WeakPolarHBondContact O-CD2 3.31Å; V156-F160 PolarHBondContact O-N 2.91Å; S157-F160 PolarHBondContact O-N 3.03Å; F160-W162 PolarHBondContact O-N 3.45Å; F160-L163 HydrophobicContact CD1-CD2 4.28Å; F160-L163 PolarHBondContact O-N 2.92Å; F160-F164 HydrophobicContact CB-CD2 4.41Å; F160-F164 HydrophobicContact CB-CE2 3.8Å; F160-F164 HydrophobicContact CB-CZ 4.43Å; F160-F164 AromaticContact CD1-CE2 3.99Å; F160-F164 HydrophobicContact CD1-CE2 3.99Å; F160-F164 AromaticContact CD1-CZ 3.75Å; F160-F164 HydrophobicContact CD1-CZ 3.75Å; F160-F164 HydrophobicContact CE1-CZ 4.48Å; F160-F164 HydrophobicContact CG-CE2 4.2Å; F160-F164 HydrophobicContact CG-CZ 4.41Å; F160-F164 WeakPolarHBondContact O-CD2 3.32Å; F160-F164 WeakPolarHBondContact O-CG 3.47Å; F160-F164 PolarHBondContact O-N 3.34Å; F160-F164 VanDerWaalsContact O-N 3.12Å
161	F	95.4	Very high	94.6	Very high	2 Å²	2	24.6 Å²	24.6	1%	0.009	12%	0.115	C	C	.	.	H	α-helix	trans	-52.4	-59.9	173.6	-176.4	-105.1	0	0	0	110.1	L130 N134 S157 A158 M159 L163 F164 V165 W327 F330 L357 Y361	L130-F161 HydrophobicContact CD1-CD2 3.92Å; L130-F161 HydrophobicContact CD1-CE2 4.49Å; N134-F161 WeakPolarHBondContact ND2-CA 3.35Å; N134-F161 WeakPolarHBondContact ND2-CB 3.33Å; N134-F161 PolarHBondContact ND2-N 3.44Å; S157-F161 WeakPolarHBondContact O-CB 3.3Å; S157-F161 PolarHBondContact O-N 2.83Å; A158-F161 WeakPolarHBondContact O-CB 3.32Å; A158-F161 PolarHBondContact O-N 3.41Å; M159-F161 VanDerWaalsContact C-N 3.33Å; M159-F161 PolarHBondContact O-N 3.43Å; F161-L163 VanDerWaalsContact C-N 3.34Å; F161-L163 PolarHBondContact O-N 3.48Å; F161-F164 PolarHBondContact O-N 2.86Å; F161-V165 HydrophobicContact CD1-CG2 4.35Å; F161-V165 HydrophobicContact CE1-CG2 4.2Å; F161-V165 HydrophobicContact CE2-CG2 4.37Å; F161-V165 HydrophobicContact CZ-CG2 4.22Å; F161-V165 WeakPolarHBondContact O-CB 3.31Å; F161-V165 WeakPolarHBondContact O-CG2 3.41Å; F161-V165 PolarHBondContact O-N 3.23Å; F161-V165 VanDerWaalsContact O-N 3.12Å; F161-W327 HydrophobicContact CE1-CH2 4.01Å; F161-W327 HydrophobicContact CE1-CZ3 4.33Å; F161-W327 HydrophobicContact CE2-CH2 4.41Å; F161-W327 AromaticContact CZ-CH2 3.63Å; F161-W327 HydrophobicContact CZ-CH2 3.63Å; F161-W327 HydrophobicContact CZ-CZ3 4.23Å; F161-F330 AromaticContact CE1-CE1 3.77Å; F161-F330 HydrophobicContact CE1-CE1 3.77Å; F161-F330 HydrophobicContact CE1-CZ 4.02Å; F161-F330 HydrophobicContact CZ-CE1 4.02Å; F161-F330 HydrophobicContact CZ-CZ 4.15Å; F161-L357 HydrophobicContact CD2-CD1 4.43Å; F161-L357 HydrophobicContact CE2-CD1 3.47Å; F161-L357 VanDerWaalsContact CE2-CD1 3.47Å; F161-L357 HydrophobicContact CZ-CD1 3.7Å; F161-Y361 HydrophobicContact CD2-CE1 4.29Å; F161-Y361 AromaticContact CE2-CE1 3.98Å; F161-Y361 HydrophobicContact CE2-CE1 3.98Å
162	W	95.8	Very high	94.9	Very high	8 Å²	8	20.6 Å²	20.6	3%	0.03	10%	0.098	C	C	.	.	H	α-helix	trans	-68	-32.4	-175.5	-72.9	109.7	0	0	0	113	A158 M159 F160 V165 I166 A210 L213 F231 I246 W327 F330	A158-W162 PolarHBondContact O-N 2.89Å; A158-W162 VanDerWaalsContact O-N 3.07Å; M159-W162 PolarHBondContact O-N 3.22Å; F160-W162 PolarHBondContact O-N 3.45Å; W162-V165 HydrophobicContact CE3-CB 4.47Å; W162-V165 HydrophobicContact CE3-CG1 4.16Å; W162-V165 HydrophobicContact CZ3-CG1 4.26Å; W162-V165 PolarHBondContact O-N 3.41Å; W162-I166 HydrophobicContact CB-CD1 4.49Å; W162-I166 WeakPolarHBondContact O-CB 3.41Å; W162-I166 WeakPolarHBondContact O-CD1 3.16Å; W162-I166 WeakPolarHBondContact O-CG1 3.31Å; W162-I166 PolarHBondContact O-N 2.91Å; W162-A210 HydrophobicContact CB-CB 4.21Å; W162-L213 HydrophobicContact CB-CD1 4.3Å; W162-L213 VanDerWaalsContact CD1-CD1 3.44Å; W162-L213 HydrophobicContact CG-CD1 4.13Å; W162-F231 AromaticContact CE2-CE2 3.46Å; W162-F231 VanDerWaalsContact CE2-CE2 3.46Å; W162-F231 AromaticContact CE2-CZ 3.79Å; W162-F231 HydrophobicContact CH2-CE2 4.24Å; W162-F231 AromaticContact CZ2-CD2 3.96Å; W162-F231 HydrophobicContact CZ2-CD2 3.96Å; W162-F231 AromaticContact CZ2-CE2 3.31Å; W162-F231 HydrophobicContact CZ2-CE2 3.31Å; W162-F231 HydrophobicContact CZ2-CZ 4.12Å; W162-F231 AromaticContact NE1-CE2 3.48Å; W162-F231 AromaticContact NE1-CZ 3.36Å; W162-I246 HydrophobicContact CD2-CD1 4.22Å; W162-I246 HydrophobicContact CD2-CG2 3.81Å; W162-I246 HydrophobicContact CE3-CG2 3.39Å; W162-I246 HydrophobicContact CG-CD1 4.16Å; W162-I246 HydrophobicContact CH2-CG2 3.62Å; W162-I246 HydrophobicContact CZ2-CG2 4.03Å; W162-I246 HydrophobicContact CZ3-CG2 3.28Å; W162-W327 HydrophobicContact CZ3-CZ3 4.28Å; W162-F330 HydrophobicContact CH2-CD1 4.49Å; W162-F330 AromaticContact CH2-CE1 3.86Å; W162-F330 HydrophobicContact CH2-CE1 3.86Å; W162-F330 AromaticContact CZ2-CE1 3.89Å; W162-F330 HydrophobicContact CZ2-CE1 3.89Å
163	L	97.8	Very high	95.1	Very high	9 Å²	9	15.1 Å²	15.1	5%	0.047	8%	0.076	C	C	.	.	H	α-helix	trans	-56.6	-56.1	173.5	171.6	58.3	0	0	0	111.8	M159 F160 F161 V165 I166 E167 W203 S206 F207 A210	M159-L163 HydrophobicContact CE-CB 3.59Å; M159-L163 HydrophobicContact CE-CD2 3.39Å; M159-L163 HydrophobicContact CE-CG 4.07Å; M159-L163 WeakPolarHBondContact O-CB 3.35Å; M159-L163 PolarHBondContact O-N 3.34Å; F160-L163 HydrophobicContact CD1-CD2 4.28Å; F160-L163 PolarHBondContact O-N 2.92Å; F161-L163 VanDerWaalsContact C-N 3.34Å; F161-L163 PolarHBondContact O-N 3.48Å; L163-V165 VanDerWaalsContact C-N 3.26Å; L163-V165 PolarHBondContact O-N 3.35Å; L163-I166 PolarHBondContact O-N 2.93Å; L163-E167 WeakPolarHBondContact O-CB 3.41Å; L163-E167 PolarHBondContact O-N 2.86Å; L163-W203 HydrophobicContact CD1-CE3 4.32Å; L163-W203 HydrophobicContact CD1-CZ3 4.39Å; L163-W203 HydrophobicContact CD2-CZ3 4.3Å; L163-W203 HydrophobicContact CG-CZ3 4.28Å; L163-S206 VanDerWaalsContact CD1-C 3.49Å; L163-F207 HydrophobicContact CD1-CB 4.12Å; L163-F207 HydrophobicContact CD2-CD2 4.43Å; L163-A210 HydrophobicContact CB-CB 4.04Å
164	F	97.6	Very high	95.4	Very high	5 Å²	5	14 Å²	14	2%	0.022	7%	0.072	C	C	.	.	H	α-helix	trans	-69.8	-28.7	-176.1	-57	-44.4	0	0	0	112.4	A126 L129 L130 L133 F160 F161 G168 W203	A126-F164 HydrophobicContact CB-CB 4.33Å; A126-F164 HydrophobicContact CB-CD1 4.35Å; L129-F164 HydrophobicContact CB-CD1 4.04Å; L129-F164 HydrophobicContact CB-CD2 4.2Å; L129-F164 HydrophobicContact CB-CE1 3.59Å; L129-F164 HydrophobicContact CB-CE2 3.76Å; L129-F164 HydrophobicContact CB-CG 4.36Å; L129-F164 HydrophobicContact CB-CZ 3.46Å; L129-F164 VanDerWaalsContact CB-CZ 3.46Å; L129-F164 HydrophobicContact CD1-CD1 4.32Å; L129-F164 HydrophobicContact CD1-CE1 3.52Å; L129-F164 HydrophobicContact CD1-CZ 3.92Å; L129-F164 HydrophobicContact CG-CE1 4.22Å; L129-F164 HydrophobicContact CG-CZ 4.28Å; L130-F164 HydrophobicContact CB-CB 4.15Å; L130-F164 HydrophobicContact CB-CD2 4.03Å; L130-F164 HydrophobicContact CB-CG 4.4Å; L130-F164 HydrophobicContact CD1-CD2 4.34Å; L133-F164 HydrophobicContact CB-CE2 4.28Å; L133-F164 HydrophobicContact CD1-CE2 3.71Å; L133-F164 HydrophobicContact CD1-CZ 3.62Å; F160-F164 HydrophobicContact CB-CD2 4.41Å; F160-F164 HydrophobicContact CB-CE2 3.8Å; F160-F164 HydrophobicContact CB-CZ 4.43Å; F160-F164 AromaticContact CD1-CE2 3.99Å; F160-F164 HydrophobicContact CD1-CE2 3.99Å; F160-F164 AromaticContact CD1-CZ 3.75Å; F160-F164 HydrophobicContact CD1-CZ 3.75Å; F160-F164 HydrophobicContact CE1-CZ 4.48Å; F160-F164 HydrophobicContact CG-CE2 4.2Å; F160-F164 HydrophobicContact CG-CZ 4.41Å; F160-F164 WeakPolarHBondContact O-CD2 3.32Å; F160-F164 WeakPolarHBondContact O-CG 3.47Å; F160-F164 PolarHBondContact O-N 3.34Å; F160-F164 VanDerWaalsContact O-N 3.12Å; F161-F164 PolarHBondContact O-N 2.86Å; F164-G168 PolarHBondContact O-N 2.94Å; F164-W203 AromaticContact CD1-CH2 3.88Å; F164-W203 HydrophobicContact CD1-CH2 3.88Å; F164-W203 HydrophobicContact CD1-CZ3 4.04Å; F164-W203 AromaticContact CE1-CH2 3.91Å; F164-W203 HydrophobicContact CE1-CH2 3.91Å; F164-W203 AromaticContact CE1-CZ3 3.89Å; F164-W203 HydrophobicContact CE1-CZ3 3.89Å
165	V	95.4	Very high	95.5	Very high	7 Å²	7	14.2 Å²	14.2	4%	0.042	7%	0.073	C	C	.	.	H	α-helix	trans	-67.1	-52.4	174.5	169.8	0	0	0	0	110.9	F161 W162 L163 E167 G168 V169 W327	F161-V165 HydrophobicContact CD1-CG2 4.35Å; F161-V165 HydrophobicContact CE1-CG2 4.2Å; F161-V165 HydrophobicContact CE2-CG2 4.37Å; F161-V165 HydrophobicContact CZ-CG2 4.22Å; F161-V165 WeakPolarHBondContact O-CB 3.31Å; F161-V165 WeakPolarHBondContact O-CG2 3.41Å; F161-V165 PolarHBondContact O-N 3.23Å; F161-V165 VanDerWaalsContact O-N 3.12Å; W162-V165 HydrophobicContact CE3-CB 4.47Å; W162-V165 HydrophobicContact CE3-CG1 4.16Å; W162-V165 HydrophobicContact CZ3-CG1 4.26Å; W162-V165 PolarHBondContact O-N 3.41Å; L163-V165 VanDerWaalsContact C-N 3.26Å; L163-V165 PolarHBondContact O-N 3.35Å; V165-E167 VanDerWaalsContact C-N 3.32Å; V165-E167 PolarHBondContact O-N 3.36Å; V165-G168 PolarHBondContact O-N 3.31Å; V165-V169 WeakPolarHBondContact O-CB 3.42Å; V165-V169 VanDerWaalsContact O-CG2 3.25Å; V165-V169 WeakPolarHBondContact O-CG2 3.5Å; V165-V169 PolarHBondContact O-N 3.25Å; V165-W327 HydrophobicContact CB-CH2 3.8Å; V165-W327 HydrophobicContact CB-CZ2 4.07Å; V165-W327 HydrophobicContact CB-CZ3 4.43Å; V165-W327 HydrophobicContact CG1-CD2 4.39Å; V165-W327 HydrophobicContact CG1-CE3 4.05Å; V165-W327 HydrophobicContact CG1-CH2 3.26Å; V165-W327 HydrophobicContact CG1-CZ2 3.59Å; V165-W327 HydrophobicContact CG1-CZ3 3.47Å; V165-W327 VanDerWaalsContact CG1-CZ3 3.47Å; V165-W327 HydrophobicContact CG2-CH2 3.12Å; V165-W327 HydrophobicContact CG2-CZ2 3.41Å; V165-W327 VanDerWaalsContact CG2-CZ2 3.41Å; V165-W327 HydrophobicContact CG2-CZ3 4.11Å
166	I	97	Very high	95.5	Very high	6 Å²	6	12.2 Å²	12.2	3%	0.031	7%	0.066	C	C	.	.	H	α-helix	trans	-63.4	-41.8	-179.6	-64.3	164	0	0	0	110	W162 L163 V169 A170 S206 V209 I249	W162-I166 HydrophobicContact CB-CD1 4.49Å; W162-I166 WeakPolarHBondContact O-CB 3.41Å; W162-I166 WeakPolarHBondContact O-CD1 3.16Å; W162-I166 WeakPolarHBondContact O-CG1 3.31Å; W162-I166 PolarHBondContact O-N 2.91Å; L163-I166 PolarHBondContact O-N 2.93Å; I166-V169 PolarHBondContact O-N 3.09Å; I166-A170 WeakPolarHBondContact O-CB 3.44Å; I166-A170 PolarHBondContact O-N 3.07Å; I166-S206 WeakPolarHBondContact CG2-OG 3.36Å; I166-V209 HydrophobicContact CD1-CB 4.1Å; I166-V209 HydrophobicContact CD1-CG1 3.63Å; I166-I249 HydrophobicContact CG2-CG2 3.88Å
167	E	97.9	Very high	95.5	Very high	0 Å²	0	14.1 Å²	14.1	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-60.5	-49.8	175.3	171.4	59.2	-165.2	0	0	111.1	S122 A126 L163 V165 V169 A170 I171 S202 W203 S206	S122-E167 PolarHBondContact OG-OE1 3.45Å; A126-E167 HydrophobicContact CB-CB 4.44Å; A126-E167 HydrophobicContact CB-CG 3.93Å; L163-E167 WeakPolarHBondContact O-CB 3.41Å; L163-E167 PolarHBondContact O-N 2.86Å; V165-E167 VanDerWaalsContact C-N 3.32Å; V165-E167 PolarHBondContact O-N 3.36Å; E167-V169 VanDerWaalsContact C-N 3.25Å; E167-V169 PolarHBondContact O-N 3.27Å; E167-A170 PolarHBondContact O-N 3.4Å; E167-I171 WeakPolarHBondContact O-CG1 3.32Å; E167-I171 PolarHBondContact O-N 3.44Å; E167-I171 WeakPolarHBondContact OE1-CD1 3.38Å; E167-I171 VanDerWaalsContact OE1-CG1 3.3Å; E167-I171 WeakPolarHBondContact OE1-CG1 3.47Å; E167-S202 PolarHBondContact OE1-OG 3.31Å; E167-S202 VanDerWaalsContact OE2-C 3.23Å; E167-S202 VanDerWaalsContact OE2-CB 3.22Å; E167-S202 WeakPolarHBondContact OE2-CB 3.34Å; E167-S202 PolarHBondContact OE2-OG 2.91Å; E167-W203 HydrophobicContact CG-CD2 4.11Å; E167-W203 HydrophobicContact CG-CH2 4.22Å; E167-W203 HydrophobicContact CG-CZ2 3.73Å; E167-W203 PolarHBondContact OE1-NE1 3.26Å; E167-W203 PolarHBondContact OE2-N 2.98Å; E167-S206 WeakPolarHBondContact CA-OG 3.41Å; E167-S206 PolarHBondContact N-OG 3.45Å
168	G	96.2	Very high	95.5	Very high	1 Å²	1	14.5 Å²	14.5	1%	0.01	8%	0.077	C	C	.	.	H	α-helix	trans	-59.2	-38.2	179.7	0	0	0	0	0	112.8	L123 F164 V165 L172	L123-G168 VanDerWaalsContact CD1-CA 3.43Å; F164-G168 PolarHBondContact O-N 2.94Å; V165-G168 PolarHBondContact O-N 3.31Å; G168-L172 WeakPolarHBondContact O-CG 3.39Å; G168-L172 PolarHBondContact O-N 2.85Å; G168-L172 VanDerWaalsContact O-N 3.13Å
169	V	95.7	Very high	95.3	Very high	3 Å²	3	17 Å²	17	2%	0.018	9%	0.086	C	C	.	.	H	α-helix	trans	-70.7	-42.2	176.7	173.4	0	0	0	0	112.2	V165 I166 E167 I171 L172 L173 P254 F323	V165-V169 WeakPolarHBondContact O-CB 3.42Å; V165-V169 VanDerWaalsContact O-CG2 3.25Å; V165-V169 WeakPolarHBondContact O-CG2 3.5Å; V165-V169 PolarHBondContact O-N 3.25Å; I166-V169 PolarHBondContact O-N 3.09Å; E167-V169 VanDerWaalsContact C-N 3.25Å; E167-V169 PolarHBondContact O-N 3.27Å; V169-I171 VanDerWaalsContact C-N 3.29Å; V169-I171 PolarHBondContact O-N 2.91Å; V169-L172 PolarHBondContact O-N 3.34Å; V169-L173 WeakPolarHBondContact O-CB 3.15Å; V169-L173 PolarHBondContact O-N 2.99Å; V169-P254 HydrophobicContact CG1-CB 3.5Å; V169-P254 VanDerWaalsContact CG1-CB 3.5Å; V169-P254 HydrophobicContact CG1-CG 3.28Å; V169-F323 HydrophobicContact CG1-CZ 4.31Å; V169-F323 HydrophobicContact CG2-CD2 4.17Å; V169-F323 HydrophobicContact CG2-CE2 3.35Å; V169-F323 HydrophobicContact CG2-CZ 3.91Å
170	A	97.1	Very high	95	Very high	24 Å²	24	17.5 Å²	17.5	20%	0.198	9%	0.088	C	C	.	.	H	α-helix	trans	-58.8	-42.4	175.6	0	0	0	0	0	111.2	I166 E167 L173 I174	I166-A170 WeakPolarHBondContact O-CB 3.44Å; I166-A170 PolarHBondContact O-N 3.07Å; E167-A170 PolarHBondContact O-N 3.4Å; A170-L173 WeakPolarHBondContact O-CB 3.11Å; A170-L173 PolarHBondContact O-N 3.38Å; A170-I174 WeakPolarHBondContact O-CD1 3.39Å; A170-I174 VanDerWaalsContact O-CG1 3.25Å; A170-I174 WeakPolarHBondContact O-CG1 3.49Å; A170-I174 PolarHBondContact O-N 3.35Å
171	I	96.7	Very high	94.7	Very high	0 Å²	0	16.5 Å²	16.5	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-65.6	-43.7	176.7	-62.7	-60.9	0	0	0	112	L119 L123 E167 V169 L173 I174 I175 I199	L119-I171 HydrophobicContact CB-CG2 4.03Å; L119-I171 HydrophobicContact CD2-CD1 3.89Å; L119-I171 WeakPolarHBondContact O-CG2 3.46Å; L123-I171 HydrophobicContact CB-CB 4.37Å; L123-I171 HydrophobicContact CB-CG2 3.89Å; E167-I171 WeakPolarHBondContact O-CG1 3.32Å; E167-I171 PolarHBondContact O-N 3.44Å; E167-I171 WeakPolarHBondContact OE1-CD1 3.38Å; E167-I171 VanDerWaalsContact OE1-CG1 3.3Å; E167-I171 WeakPolarHBondContact OE1-CG1 3.47Å; V169-I171 VanDerWaalsContact C-N 3.29Å; V169-I171 PolarHBondContact O-N 2.91Å; I171-L173 VanDerWaalsContact C-N 3.28Å; I171-L173 PolarHBondContact O-N 3.49Å; I171-I174 HydrophobicContact CD1-CD1 4.28Å; I171-I174 PolarHBondContact O-N 3.28Å; I171-I175 HydrophobicContact CG2-CD1 3.91Å; I171-I175 HydrophobicContact CG2-CG1 4.47Å; I171-I175 VanDerWaalsContact O-CG1 3.32Å; I171-I175 WeakPolarHBondContact O-CG1 3.26Å; I171-I175 PolarHBondContact O-N 2.92Å; I171-I199 HydrophobicContact CD1-CG1 3.89Å
172	L	93.8	Very high	94.3	Very high	12 Å²	12	18.5 Å²	18.5	6%	0.063	10%	0.095	C	C	.	.	H	α-helix	trans	-61.3	-38.6	175.4	-73.3	174.6	0	0	0	112.1	L123 G168 V169 S176 L319 F323	L123-L172 HydrophobicContact CD2-CD2 3.96Å; L123-L172 HydrophobicContact CD2-CG 4.29Å; G168-L172 WeakPolarHBondContact O-CG 3.39Å; G168-L172 PolarHBondContact O-N 2.85Å; G168-L172 VanDerWaalsContact O-N 3.13Å; V169-L172 PolarHBondContact O-N 3.34Å; L172-S176 WeakPolarHBondContact O-CB 3.46Å; L172-S176 PolarHBondContact O-N 3Å; L172-S176 PolarHBondContact O-OG 3.24Å; L172-L319 HydrophobicContact CD2-CB 4.33Å; L172-F323 HydrophobicContact CD1-CB 4.2Å; L172-F323 HydrophobicContact CD1-CD2 4.28Å; L172-F323 HydrophobicContact CD1-CG 4.34Å
173	L	95.5	Very high	93.8	Very high	38 Å²	38	19.8 Å²	19.8	20%	0.199	10%	0.102	C	C	.	.	H	α-helix	trans	-63.3	-48.1	174.9	-178.1	63.7	0	0	0	111.5	V169 A170 I171 I175 S176 I177 V257 I258	V169-L173 WeakPolarHBondContact O-CB 3.15Å; V169-L173 PolarHBondContact O-N 2.99Å; A170-L173 WeakPolarHBondContact O-CB 3.11Å; A170-L173 PolarHBondContact O-N 3.38Å; I171-L173 VanDerWaalsContact C-N 3.28Å; I171-L173 PolarHBondContact O-N 3.49Å; L173-I175 VanDerWaalsContact C-N 3.35Å; L173-I175 PolarHBondContact O-N 3.05Å; L173-S176 PolarHBondContact O-N 3.4Å; L173-S176 VanDerWaalsContact O-N 3.12Å; L173-I177 HydrophobicContact CD1-CD1 4.03Å; L173-I177 HydrophobicContact CD1-CG1 4.36Å; L173-I177 HydrophobicContact CG-CD1 3.94Å; L173-I177 WeakPolarHBondContact O-CG1 3.39Å; L173-I177 PolarHBondContact O-N 3.04Å; L173-V257 HydrophobicContact CD1-CB 3.75Å; L173-V257 HydrophobicContact CD1-CG1 3.55Å; L173-I258 HydrophobicContact CD1-CD1 4.37Å; L173-I258 HydrophobicContact CD1-CG1 3.77Å
174	I	96	Very high	93.3	Very high	31 Å²	31	21.2 Å²	21.2	16%	0.159	11%	0.112	C	C	.	.	H	α-helix	trans	-57.8	-47.1	176.8	-68.3	159.8	0	0	0	110.8	L119 A170 I171 S176 I177 D178 L198	L119-I174 HydrophobicContact CD1-CG2 3.69Å; L119-I174 HydrophobicContact CD2-CG2 4.04Å; A170-I174 WeakPolarHBondContact O-CD1 3.39Å; A170-I174 VanDerWaalsContact O-CG1 3.25Å; A170-I174 WeakPolarHBondContact O-CG1 3.49Å; A170-I174 PolarHBondContact O-N 3.35Å; I171-I174 HydrophobicContact CD1-CD1 4.28Å; I171-I174 PolarHBondContact O-N 3.28Å; I174-S176 VanDerWaalsContact C-N 3.28Å; I174-S176 PolarHBondContact O-N 2.86Å; I174-I177 PolarHBondContact O-N 3.46Å; I174-D178 WeakPolarHBondContact O-CB 3.25Å; I174-D178 PolarHBondContact O-N 3.2Å; I174-L198 HydrophobicContact CD1-CB 4.1Å; I174-L198 HydrophobicContact CG2-CD1 3.98Å
175	I	93.3	Very high	92.7	Very high	4 Å²	4	25.3 Å²	25.3	2%	0.021	13%	0.131	C	C	.	.	H	α-helix	trans	-61	-39.5	177.6	-67.5	168.4	0	0	0	110.8	L119 L120 I171 L173 R179 I316	L119-I175 HydrophobicContact CB-CD1 4.16Å; L119-I175 HydrophobicContact CB-CG1 4.09Å; L119-I175 HydrophobicContact CD1-CG1 3.93Å; L120-I175 HydrophobicContact CD2-CD1 3.78Å; L120-I175 HydrophobicContact CG-CD1 4.41Å; I171-I175 HydrophobicContact CG2-CD1 3.91Å; I171-I175 HydrophobicContact CG2-CG1 4.47Å; I171-I175 VanDerWaalsContact O-CG1 3.32Å; I171-I175 WeakPolarHBondContact O-CG1 3.26Å; I171-I175 PolarHBondContact O-N 2.92Å; L173-I175 VanDerWaalsContact C-N 3.35Å; L173-I175 PolarHBondContact O-N 3.05Å; I175-R179 HydrophobicContact CG2-CG 4.49Å; I175-R179 WeakPolarHBondContact O-CB 3.48Å; I175-R179 WeakPolarHBondContact O-CG 3.36Å; I175-R179 PolarHBondContact O-N 3.32Å; I175-R179 VanDerWaalsContact O-N 3.13Å; I175-I316 HydrophobicContact CG2-CD1 4.33Å; I175-I316 HydrophobicContact CG2-CG1 4.31Å; I175-I316 HydrophobicContact CG2-CG2 4.45Å
176	S	91.9	Very high	92.3	Very high	5 Å²	5	34.4 Å²	34.4	4%	0.035	16%	0.164	C	C	.	.	H	α-helix	trans	-71	-41.5	-177.2	-58.6	0	0	0	0	111.8	L172 L173 I174 R179 F180	L172-S176 WeakPolarHBondContact O-CB 3.46Å; L172-S176 PolarHBondContact O-N 3Å; L172-S176 PolarHBondContact O-OG 3.24Å; L173-S176 PolarHBondContact O-N 3.4Å; L173-S176 VanDerWaalsContact O-N 3.12Å; I174-S176 VanDerWaalsContact C-N 3.28Å; I174-S176 PolarHBondContact O-N 2.86Å; S176-R179 PolarHBondContact O-N 3.48Å; S176-F180 PolarHBondContact O-N 3.04Å
177	I	93.8	Very high	91.7	Very high	65 Å²	65	37.5 Å²	37.5	33%	0.333	18%	0.179	S	C	.	.	H	α-helix	trans	-64.8	-47.7	175	-67.4	169.6	0	0	0	110.5	L173 I174 R179 F180 L181 V257	L173-I177 HydrophobicContact CD1-CD1 4.03Å; L173-I177 HydrophobicContact CD1-CG1 4.36Å; L173-I177 HydrophobicContact CG-CD1 3.94Å; L173-I177 WeakPolarHBondContact O-CG1 3.39Å; L173-I177 PolarHBondContact O-N 3.04Å; I174-I177 PolarHBondContact O-N 3.46Å; I177-R179 PolarHBondContact O-N 3.43Å; I177-F180 WeakPolarHBondContact O-CB 3.04Å; I177-F180 PolarHBondContact O-N 3.16Å; I177-F180 VanDerWaalsContact O-N 3.11Å; I177-L181 HydrophobicContact CG2-CD1 4.04Å; I177-L181 HydrophobicContact CG2-CG 4.21Å; I177-L181 WeakPolarHBondContact O-CG 3.41Å; I177-L181 PolarHBondContact O-N 2.87Å; I177-V257 HydrophobicContact CD1-CG1 4.2Å; I177-V257 HydrophobicContact CG1-CG1 4.17Å
178	D	92.3	Very high	91.3	Very high	11 Å²	11	43.3 Å²	43.3	6%	0.059	21%	0.21	C	C	.	.	H	α-helix	trans	-51.3	-45.8	175.6	173.3	72.7	0	0	0	111.4	I174 F180 L181 I182 L190	I174-D178 WeakPolarHBondContact O-CB 3.25Å; I174-D178 PolarHBondContact O-N 3.2Å; D178-F180 PolarHBondContact O-N 3.15Å; D178-L181 PolarHBondContact O-N 3.1Å; D178-I182 WeakPolarHBondContact O-CG1 3.38Å; D178-I182 PolarHBondContact O-N 3.15Å; D178-I182 WeakPolarHBondContact OD2-CD1 3.44Å; D178-L190 HydrophobicContact CB-CD2 4.05Å; D178-L190 WeakPolarHBondContact OD1-CB 3.32Å; D178-L190 WeakPolarHBondContact OD1-CD2 3.36Å
179	R	89.3	Confident	90.9	Very high	55 Å²	55	48.8 Å²	48.8	21%	0.208	23%	0.233	C	C	.	.	H	α-helix	trans	-67.1	-39.1	-179.5	-68.7	-77	-179.6	-137	14.3	112.8	I116 I175 S176 I177 I183 I265 I316	I116-R179 VanDerWaalsContact CD1-NH1 3.3Å; I175-R179 HydrophobicContact CG2-CG 4.49Å; I175-R179 WeakPolarHBondContact O-CB 3.48Å; I175-R179 WeakPolarHBondContact O-CG 3.36Å; I175-R179 PolarHBondContact O-N 3.32Å; I175-R179 VanDerWaalsContact O-N 3.13Å; S176-R179 PolarHBondContact O-N 3.48Å; I177-R179 PolarHBondContact O-N 3.43Å; R179-I183 WeakPolarHBondContact O-CB 3.25Å; R179-I183 VanDerWaalsContact O-CG1 3.28Å; R179-I183 WeakPolarHBondContact O-CG1 3.47Å; R179-I183 PolarHBondContact O-N 2.91Å; R179-I265 HydrophobicContact CB-CD1 4.19Å; R179-I316 HydrophobicContact CB-CD1 4.49Å; R179-I316 HydrophobicContact CG-CD1 3.49Å; R179-I316 VanDerWaalsContact CG-CD1 3.49Å
180	F	90.1	Very high	90.8	Very high	19 Å²	19	49.9 Å²	49.9	8%	0.083	24%	0.239	C	C	.	.	H	α-helix	trans	-62.7	-46.1	172.9	175.6	-98	0	0	0	111.5	S176 I177 D178 I182 I183 V184 Q185 Y260 I265	S176-F180 PolarHBondContact O-N 3.04Å; I177-F180 WeakPolarHBondContact O-CB 3.04Å; I177-F180 PolarHBondContact O-N 3.16Å; I177-F180 VanDerWaalsContact O-N 3.11Å; D178-F180 PolarHBondContact O-N 3.15Å; F180-I182 PolarHBondContact O-N 3.05Å; F180-I183 PolarHBondContact O-N 3.39Å; F180-V184 HydrophobicContact CD2-CB 3.95Å; F180-V184 HydrophobicContact CD2-CG1 4.47Å; F180-V184 HydrophobicContact CD2-CG2 3.55Å; F180-V184 HydrophobicContact CE2-CB 3.84Å; F180-V184 HydrophobicContact CE2-CG1 3.86Å; F180-V184 HydrophobicContact CE2-CG2 3.73Å; F180-V184 HydrophobicContact CG-CB 4.48Å; F180-V184 HydrophobicContact CG-CG2 4.35Å; F180-V184 HydrophobicContact CZ-CB 4.27Å; F180-V184 HydrophobicContact CZ-CG1 4.11Å; F180-V184 WeakPolarHBondContact O-CA 3.45Å; F180-V184 VanDerWaalsContact O-CB 3.29Å; F180-V184 WeakPolarHBondContact O-CB 3.34Å; F180-V184 PolarHBondContact O-N 3.39Å; F180-Q185 HydrophobicContact CE1-CG 4.14Å; F180-Q185 PolarHBondContact O-N 2.93Å; F180-Y260 HydrophobicContact CE1-CE1 4.36Å; F180-Y260 HydrophobicContact CE2-CE1 4.1Å; F180-Y260 AromaticContact CZ-CE1 3.77Å; F180-Y260 HydrophobicContact CZ-CE1 3.77Å; F180-I265 HydrophobicContact CB-CD1 4.43Å
181	L	90.3	Very high	90.6	Very high	42 Å²	42	52 Å²	52	22%	0.22	25%	0.247	C	C	.	.	H	α-helix	trans	-60.3	-46.7	178.4	-66.9	178.3	0	0	0	111.7	I177 D178 Q185 R186 Q187	I177-L181 HydrophobicContact CG2-CD1 4.04Å; I177-L181 HydrophobicContact CG2-CG 4.21Å; I177-L181 WeakPolarHBondContact O-CG 3.41Å; I177-L181 PolarHBondContact O-N 2.87Å; D178-L181 PolarHBondContact O-N 3.1Å; L181-Q185 HydrophobicContact CD2-CG 4.45Å; L181-Q185 CarbonylContact O-C 3.31Å; L181-Q185 VanDerWaalsContact O-C 3.31Å; L181-Q185 WeakPolarHBondContact O-CA 3.45Å; L181-Q185 WeakPolarHBondContact O-CB 3.28Å; L181-Q185 PolarHBondContact O-N 3.4Å; L181-R186 PolarHBondContact O-N 3.12Å; L181-Q187 CarbonylContact C-O 3.32Å; L181-Q187 HydrophobicContact CB-CB 4.46Å; L181-Q187 PolarHBondContact O-N 2.97Å
182	I	87.3	Confident	90.5	Very high	43 Å²	43	54.6 Å²	54.6	22%	0.221	26%	0.264	C	S	.	.	H	α-helix	trans	-66.9	-44.2	-179.6	-68.2	170	0	0	0	111.7	D178 F180 R186 Q187 D188	D178-I182 WeakPolarHBondContact O-CG1 3.38Å; D178-I182 PolarHBondContact O-N 3.15Å; D178-I182 WeakPolarHBondContact OD2-CD1 3.44Å; F180-I182 PolarHBondContact O-N 3.05Å; I182-R186 VanDerWaalsContact O-CA 3.3Å; I182-R186 WeakPolarHBondContact O-CA 3.33Å; I182-R186 PolarHBondContact O-N 3.39Å; I182-Q187 WeakPolarHBondContact CA-O 3.28Å; I182-Q187 WeakPolarHBondContact CG1-O 3.44Å; I182-Q187 PolarHBondContact N-O 2.99Å; I182-D188 HydrophobicContact CG1-CB 4.24Å
183	I	84.4	Confident	90.6	Very high	35 Å²	35	62.3 Å²	62.3	18%	0.179	29%	0.293	C	S	.	.	H	α-helix	trans	-85.7	-47.5	-170.6	-61.8	169.2	0	0	0	111.9	R179 F180 I265 T268	R179-I183 WeakPolarHBondContact O-CB 3.25Å; R179-I183 VanDerWaalsContact O-CG1 3.28Å; R179-I183 WeakPolarHBondContact O-CG1 3.47Å; R179-I183 PolarHBondContact O-N 2.91Å; F180-I183 PolarHBondContact O-N 3.39Å; I183-I265 HydrophobicContact CB-CG1 4.42Å; I183-I265 HydrophobicContact CD1-CD1 4.47Å; I183-I265 HydrophobicContact CD1-CG1 4.38Å; I183-I265 HydrophobicContact CD1-CG2 3.85Å; I183-I265 HydrophobicContact CG2-CG2 4.06Å; I183-T268 HydrophobicContact CG2-CG2 4.43Å
184	V	86.8	Confident	90.6	Very high	40 Å²	40	66.5 Å²	66.5	24%	0.242	31%	0.307	C	S	.	.	T	Hydrogen-bonded Turn	trans	-87.6	-46.8	-173	-175.5	0	0	0	0	110.5	F180 I265	F180-V184 HydrophobicContact CD2-CB 3.95Å; F180-V184 HydrophobicContact CD2-CG1 4.47Å; F180-V184 HydrophobicContact CD2-CG2 3.55Å; F180-V184 HydrophobicContact CE2-CB 3.84Å; F180-V184 HydrophobicContact CE2-CG1 3.86Å; F180-V184 HydrophobicContact CE2-CG2 3.73Å; F180-V184 HydrophobicContact CG-CB 4.48Å; F180-V184 HydrophobicContact CG-CG2 4.35Å; F180-V184 HydrophobicContact CZ-CB 4.27Å; F180-V184 HydrophobicContact CZ-CG1 4.11Å; F180-V184 WeakPolarHBondContact O-CA 3.45Å; F180-V184 VanDerWaalsContact O-CB 3.29Å; F180-V184 WeakPolarHBondContact O-CB 3.34Å; F180-V184 PolarHBondContact O-N 3.39Å; V184-I265 HydrophobicContact CG2-CB 4.48Å; V184-I265 HydrophobicContact CG2-CG1 3.93Å
185	Q	85.6	Confident	90.7	Very high	90 Å²	90	65 Å²	65	42%	0.421	30%	0.299	S	S	.	.	S	Bend	trans	-92.9	-8.4	-177	-57.8	-170.7	-3.9	0	0	113.8	F180 L181 Q187	F180-Q185 HydrophobicContact CE1-CG 4.14Å; F180-Q185 PolarHBondContact O-N 2.93Å; L181-Q185 HydrophobicContact CD2-CG 4.45Å; L181-Q185 CarbonylContact O-C 3.31Å; L181-Q185 VanDerWaalsContact O-C 3.31Å; L181-Q185 WeakPolarHBondContact O-CA 3.45Å; L181-Q185 WeakPolarHBondContact O-CB 3.28Å; L181-Q185 PolarHBondContact O-N 3.4Å; Q185-Q187 HydrophobicContact CB-CG 4.14Å; Q185-Q187 PolarHBondContact O-N 3.4Å
186	R	86.7	Confident	90.8	Very high	199 Å²	199	71.2 Å²	71.2	75%	0.751	33%	0.326	S	S	*	.			trans	55.8	32.3	-175.1	-55.7	-174.8	179.4	97.4	-0.5	113.5	L181 I182	L181-R186 PolarHBondContact O-N 3.12Å; I182-R186 VanDerWaalsContact O-CA 3.3Å; I182-R186 WeakPolarHBondContact O-CA 3.33Å; I182-R186 PolarHBondContact O-N 3.39Å
187	Q	86.1	Confident	91.1	Very high	71 Å²	71	74.1 Å²	74.1	33%	0.332	34%	0.343	S	S	.	.			trans	-107.1	113.7	177.8	-63.8	-174.9	9.5	0	0	110.1	L181 I182 Q185 K189	L181-Q187 CarbonylContact C-O 3.32Å; L181-Q187 HydrophobicContact CB-CB 4.46Å; L181-Q187 PolarHBondContact O-N 2.97Å; I182-Q187 WeakPolarHBondContact CA-O 3.28Å; I182-Q187 WeakPolarHBondContact CG1-O 3.44Å; I182-Q187 PolarHBondContact N-O 2.99Å; Q185-Q187 HydrophobicContact CB-CG 4.14Å; Q185-Q187 PolarHBondContact O-N 3.4Å; Q187-K189 VanDerWaalsContact OE1-CE 3.25Å
188	D	87.6	Confident	91.3	Very high	122 Å²	122	74.3 Å²	74.3	65%	0.652	34%	0.344	S	S	*	.			trans	-103.7	97.9	171.2	-168	-5.5	0	0	0	109.5	I182	I182-D188 HydrophobicContact CG1-CB 4.24Å
189	K	89	Confident	91.6	Very high	115 Å²	115	74.9 Å²	74.9	50%	0.5	35%	0.347	S	S	.	.			trans	-114.5	-13.2	-174.2	-74	176.6	174.9	169.6	0	112.8	Q187 R194	Q187-K189 VanDerWaalsContact OE1-CE 3.25Å; K189-R194 WeakPolarHBondContact O-CD 3.39Å; K189-R194 PolarHBondContact O-NH1 2.9Å
190	L	93	Very high	92.1	Very high	26 Å²	26	75.2 Å²	75.2	14%	0.136	36%	0.361	C	S	.	.			trans	-89.4	112.9	-172.4	-173.2	70.5	0	0	0	110.1	A115 I116 L119 D178 R194 A195 L198	A115-L190 HydrophobicContact CB-CD2 4.08Å; A115-L190 HydrophobicContact CB-CG 3.9Å; I116-L190 HydrophobicContact CG1-CD2 4.39Å; L119-L190 HydrophobicContact CD1-CD2 3.79Å; D178-L190 HydrophobicContact CB-CD2 4.05Å; D178-L190 WeakPolarHBondContact OD1-CB 3.32Å; D178-L190 WeakPolarHBondContact OD1-CD2 3.36Å; L190-R194 HydrophobicContact CD1-CB 4.43Å; L190-A195 HydrophobicContact CD1-CB 4.21Å; L190-L198 HydrophobicContact CD1-CD1 3.84Å
191	N	94.1	Very high	92.4	Very high	68 Å²	68	78.2 Å²	78.2	36%	0.364	38%	0.381	S	S	.	.			trans	-114.3	167.2	172.7	70.9	31.1	0	0	0	110.5	Y193 R194 A195	N191-Y193 PolarHBondContact O-N 2.94Å; N191-Y193 WeakPolarHBondContact OD1-CB 3.42Å; N191-Y193 PolarHBondContact OD1-N 3.49Å; N191-Y193 VanDerWaalsContact OD1-N 3.15Å; N191-R194 PolarHBondContact O-N 3.01Å; N191-R194 WeakPolarHBondContact OD1-CG 3.1Å; N191-R194 PolarHBondContact OD1-N 2.74Å; N191-A195 PolarHBondContact O-N 3.45Å
192	P	93.8	Very high	92.8	Very high	56 Å²	56	76.7 Å²	76.7	36%	0.364	37%	0.374	S	S	.	.	H	α-helix	trans	-56.9	-33.8	-177.8	-29.5	37.5	0	0	0	114.5	A115 I118 K196	A115-P192 HydrophobicContact CB-CG 4.46Å; I118-P192 HydrophobicContact CD1-CB 3.8Å; P192-K196 WeakPolarHBondContact O-CG 3.47Å; P192-K196 PolarHBondContact O-N 3.47Å; P192-K196 VanDerWaalsContact O-N 3.15Å
193	Y	95.6	Very high	93.4	Very high	174 Å²	174	77.3 Å²	77.3	68%	0.682	37%	0.374	S	S	*	.	H	α-helix	trans	-67.2	-51.5	176.9	175.2	-97.3	0	0	0	111.3	N191 A195 K196 V197	N191-Y193 PolarHBondContact O-N 2.94Å; N191-Y193 WeakPolarHBondContact OD1-CB 3.42Å; N191-Y193 PolarHBondContact OD1-N 3.49Å; N191-Y193 VanDerWaalsContact OD1-N 3.15Å; Y193-A195 VanDerWaalsContact C-N 3.29Å; Y193-A195 PolarHBondContact O-N 3.33Å; Y193-K196 PolarHBondContact O-N 3.22Å; Y193-K196 VanDerWaalsContact O-N 3.14Å; Y193-V197 HydrophobicContact CD1-CG2 4.48Å; Y193-V197 HydrophobicContact CE1-CG2 4.06Å; Y193-V197 PolarHBondContact O-N 3.25Å; Y193-V197 VanDerWaalsContact O-N 3.08Å
194	R	96.3	Very high	94	Very high	126 Å²	126	78.2 Å²	78.2	48%	0.475	39%	0.387	S	S	.	.	H	α-helix	trans	-59.1	-39.6	176.2	-72.5	177.9	176.5	-177.4	-3.1	111.8	K189 L190 N191 K196 V197 L198	K189-R194 WeakPolarHBondContact O-CD 3.39Å; K189-R194 PolarHBondContact O-NH1 2.9Å; L190-R194 HydrophobicContact CD1-CB 4.43Å; N191-R194 PolarHBondContact O-N 3.01Å; N191-R194 WeakPolarHBondContact OD1-CG 3.1Å; N191-R194 PolarHBondContact OD1-N 2.74Å; R194-K196 PolarHBondContact O-N 2.9Å; R194-V197 PolarHBondContact O-N 3.13Å; R194-L198 WeakPolarHBondContact O-CG 3.35Å; R194-L198 PolarHBondContact O-N 3.45Å
195	A	96.9	Very high	94.5	Very high	0 Å²	0	79.9 Å²	79.9	0%	0	40%	0.397	C	S	.	.	H	α-helix	trans	-60	-45.1	175.2	0	0	0	0	0	112.2	A115 L119 L190 N191 Y193 V197 L198 I199	A115-A195 HydrophobicContact CB-CB 4.05Å; L119-A195 HydrophobicContact CD2-CB 4.46Å; L119-A195 HydrophobicContact CG-CB 4.29Å; L190-A195 HydrophobicContact CD1-CB 4.21Å; N191-A195 PolarHBondContact O-N 3.45Å; Y193-A195 VanDerWaalsContact C-N 3.29Å; Y193-A195 PolarHBondContact O-N 3.33Å; A195-V197 VanDerWaalsContact C-N 3.34Å; A195-V197 PolarHBondContact O-N 3.25Å; A195-L198 PolarHBondContact O-N 2.96Å; A195-I199 WeakPolarHBondContact O-CD1 3.46Å; A195-I199 VanDerWaalsContact O-CG1 3.23Å; A195-I199 WeakPolarHBondContact O-CG1 3.13Å; A195-I199 PolarHBondContact O-N 3Å
196	K	96.7	Very high	95.1	Very high	133 Å²	133	75.7 Å²	75.7	58%	0.578	38%	0.377	S	S	*	.	H	α-helix	trans	-62.3	-39.5	176	-71	174.4	-177	-175.8	0	112.7	I118 P192 Y193 R194 I199 A200	I118-K196 HydrophobicContact CG2-CG 4.32Å; P192-K196 WeakPolarHBondContact O-CG 3.47Å; P192-K196 PolarHBondContact O-N 3.47Å; P192-K196 VanDerWaalsContact O-N 3.15Å; Y193-K196 PolarHBondContact O-N 3.22Å; Y193-K196 VanDerWaalsContact O-N 3.14Å; R194-K196 PolarHBondContact O-N 2.9Å; K196-I199 PolarHBondContact O-N 2.99Å; K196-A200 PolarHBondContact O-N 3.29Å
197	V	98.1	Very high	95.7	Very high	66 Å²	66	70.8 Å²	70.8	40%	0.4	36%	0.362	S	S	.	.	H	α-helix	trans	-64.4	-46.8	175.4	174.8	0	0	0	0	110.7	Y193 R194 A195 I199 A200 V201	Y193-V197 HydrophobicContact CD1-CG2 4.48Å; Y193-V197 HydrophobicContact CE1-CG2 4.06Å; Y193-V197 PolarHBondContact O-N 3.25Å; Y193-V197 VanDerWaalsContact O-N 3.08Å; R194-V197 PolarHBondContact O-N 3.13Å; A195-V197 VanDerWaalsContact C-N 3.34Å; A195-V197 PolarHBondContact O-N 3.25Å; V197-I199 VanDerWaalsContact C-N 3.29Å; V197-I199 PolarHBondContact O-N 3.4Å; V197-A200 PolarHBondContact O-N 3.23Å; V197-V201 WeakPolarHBondContact O-CG2 3.43Å; V197-V201 PolarHBondContact O-N 2.85Å
198	L	97.9	Very high	96.2	Very high	70 Å²	70	71.7 Å²	71.7	37%	0.366	38%	0.375	S	S	.	.	H	α-helix	trans	-59.9	-39.5	177	-71.2	172.4	0	0	0	112	I174 L190 R194 A195 V201 S202	I174-L198 HydrophobicContact CD1-CB 4.1Å; I174-L198 HydrophobicContact CG2-CD1 3.98Å; L190-L198 HydrophobicContact CD1-CD1 3.84Å; R194-L198 WeakPolarHBondContact O-CG 3.35Å; R194-L198 PolarHBondContact O-N 3.45Å; A195-L198 PolarHBondContact O-N 2.96Å; L198-V201 PolarHBondContact O-N 3.27Å; L198-S202 WeakPolarHBondContact O-CB 3.1Å; L198-S202 PolarHBondContact O-N 3.31Å; L198-S202 PolarHBondContact O-OG 3.3Å
199	I	98.4	Very high	96.6	Very high	23 Å²	23	67 Å²	67	12%	0.118	35%	0.35	C	S	.	.	H	α-helix	trans	-61.3	-50.5	173.1	-71	162.8	0	0	0	110.6	I118 L119 S122 I171 A195 K196 V197 V201 S202 W203	I118-I199 HydrophobicContact CG2-CD1 3.65Å; L119-I199 HydrophobicContact CD2-CD1 4.02Å; L119-I199 HydrophobicContact CD2-CG1 3.8Å; S122-I199 WeakPolarHBondContact OG-CG2 3.33Å; I171-I199 HydrophobicContact CD1-CG1 3.89Å; A195-I199 WeakPolarHBondContact O-CD1 3.46Å; A195-I199 VanDerWaalsContact O-CG1 3.23Å; A195-I199 WeakPolarHBondContact O-CG1 3.13Å; A195-I199 PolarHBondContact O-N 3Å; K196-I199 PolarHBondContact O-N 2.99Å; V197-I199 VanDerWaalsContact C-N 3.29Å; V197-I199 PolarHBondContact O-N 3.4Å; I199-V201 VanDerWaalsContact C-N 3.26Å; I199-V201 PolarHBondContact O-N 2.93Å; I199-S202 WeakPolarHBondContact CA-OG 3.24Å; I199-S202 PolarHBondContact O-N 2.78Å; I199-S202 VanDerWaalsContact O-N 3.13Å; I199-S202 PolarHBondContact O-OG 3.01Å; I199-W203 VanDerWaalsContact O-CD1 3.24Å; I199-W203 PolarHBondContact O-N 3.43Å
200	A	98.4	Very high	97	Very high	61 Å²	61	61.5 Å²	61.5	50%	0.504	33%	0.327	S	S	.	.	H	α-helix	trans	-58.5	-40.8	180	0	0	0	0	0	112	K196 V197 A204	K196-A200 PolarHBondContact O-N 3.29Å; V197-A200 PolarHBondContact O-N 3.23Å; A200-A204 WeakPolarHBondContact O-CB 3.38Å; A200-A204 PolarHBondContact O-N 3.46Å; A200-A204 VanDerWaalsContact O-N 3.09Å
201	V	98.4	Very high	97.1	Very high	83 Å²	83	64.5 Å²	64.5	50%	0.503	34%	0.339	S	S	.	.	H	α-helix	trans	-67.1	-41.1	175.9	173.5	0	0	0	0	111.7	V197 L198 I199 A204 T205	V197-V201 WeakPolarHBondContact O-CG2 3.43Å; V197-V201 PolarHBondContact O-N 2.85Å; L198-V201 PolarHBondContact O-N 3.27Å; I199-V201 VanDerWaalsContact C-N 3.26Å; I199-V201 PolarHBondContact O-N 2.93Å; V201-A204 PolarHBondContact O-N 2.96Å; V201-T205 WeakPolarHBondContact O-CB 3.15Å; V201-T205 PolarHBondContact O-N 3.33Å; V201-T205 PolarHBondContact O-OG1 3.44Å
202	S	98.2	Very high	97.2	Very high	10 Å²	10	63.1 Å²	63.1	7%	0.07	33%	0.334	C	S	.	.	H	α-helix	trans	-66.9	-41.4	179.2	68.4	0	0	0	0	111.8	E167 L198 I199 T205 S206	E167-S202 PolarHBondContact OE1-OG 3.31Å; E167-S202 VanDerWaalsContact OE2-C 3.23Å; E167-S202 VanDerWaalsContact OE2-CB 3.22Å; E167-S202 WeakPolarHBondContact OE2-CB 3.34Å; E167-S202 PolarHBondContact OE2-OG 2.91Å; L198-S202 WeakPolarHBondContact O-CB 3.1Å; L198-S202 PolarHBondContact O-N 3.31Å; L198-S202 PolarHBondContact O-OG 3.3Å; I199-S202 WeakPolarHBondContact CA-OG 3.24Å; I199-S202 PolarHBondContact O-N 2.78Å; I199-S202 VanDerWaalsContact O-N 3.13Å; I199-S202 PolarHBondContact O-OG 3.01Å; S202-T205 PolarHBondContact O-N 3.17Å; S202-S206 VanDerWaalsContact O-CB 3.27Å; S202-S206 WeakPolarHBondContact O-CB 3.36Å; S202-S206 PolarHBondContact O-N 2.92Å; S202-S206 PolarHBondContact O-OG 3.24Å
203	W	98.5	Very high	97.1	Very high	55 Å²	55	60.5 Å²	60.5	21%	0.208	32%	0.316	C	S	.	.	H	α-helix	trans	-61.4	-48	174.2	-85.8	95.7	0	0	0	111.8	S122 F125 A126 L129 L163 F164 E167 I199 T205 S206 F207	S122-W203 PolarHBondContact OG-NE1 3.48Å; F125-W203 HydrophobicContact CD1-CH2 4.2Å; F125-W203 AromaticContact CD1-CZ2 3.76Å; F125-W203 HydrophobicContact CD1-CZ2 3.76Å; F125-W203 HydrophobicContact CE1-CH2 4.37Å; F125-W203 HydrophobicContact CE1-CZ2 4.23Å; A126-W203 HydrophobicContact CB-CH2 4.22Å; A126-W203 HydrophobicContact CB-CZ2 4.17Å; L129-W203 HydrophobicContact CD1-CH2 4.04Å; L163-W203 HydrophobicContact CD1-CE3 4.32Å; L163-W203 HydrophobicContact CD1-CZ3 4.39Å; L163-W203 HydrophobicContact CD2-CZ3 4.3Å; L163-W203 HydrophobicContact CG-CZ3 4.28Å; F164-W203 AromaticContact CD1-CH2 3.88Å; F164-W203 HydrophobicContact CD1-CH2 3.88Å; F164-W203 HydrophobicContact CD1-CZ3 4.04Å; F164-W203 AromaticContact CE1-CH2 3.91Å; F164-W203 HydrophobicContact CE1-CH2 3.91Å; F164-W203 AromaticContact CE1-CZ3 3.89Å; F164-W203 HydrophobicContact CE1-CZ3 3.89Å; E167-W203 HydrophobicContact CG-CD2 4.11Å; E167-W203 HydrophobicContact CG-CH2 4.22Å; E167-W203 HydrophobicContact CG-CZ2 3.73Å; E167-W203 PolarHBondContact OE1-NE1 3.26Å; E167-W203 PolarHBondContact OE2-N 2.98Å; I199-W203 VanDerWaalsContact O-CD1 3.24Å; I199-W203 PolarHBondContact O-N 3.43Å; W203-T205 VanDerWaalsContact C-N 3.34Å; W203-T205 PolarHBondContact O-N 3.04Å; W203-S206 PolarHBondContact O-N 3.33Å; W203-F207 WeakPolarHBondContact O-CB 3.37Å; W203-F207 PolarHBondContact O-N 3.34Å
204	A	98.4	Very high	97	Very high	55 Å²	55	53.2 Å²	53.2	46%	0.455	29%	0.292	S	S	.	.	H	α-helix	trans	-60.3	-45.4	178.3	0	0	0	0	0	111.3	A200 V201 F207 C208	A200-A204 WeakPolarHBondContact O-CB 3.38Å; A200-A204 PolarHBondContact O-N 3.46Å; A200-A204 VanDerWaalsContact O-N 3.09Å; V201-A204 PolarHBondContact O-N 2.96Å; A204-F207 PolarHBondContact O-N 3.02Å; A204-C208 WeakPolarHBondContact O-CB 3.28Å; A204-C208 PolarHBondContact O-N 3.42Å; A204-C208 PolarHBondContact O-SG 2.97Å
205	T	97.3	Very high	96.8	Very high	75 Å²	75	52.5 Å²	52.5	46%	0.46	30%	0.297	S	S	.	.	H	α-helix	trans	-64.5	-45.9	178.9	-54.2	0	0	0	0	111.4	V201 S202 W203 F207 C208 V209	V201-T205 WeakPolarHBondContact O-CB 3.15Å; V201-T205 PolarHBondContact O-N 3.33Å; V201-T205 PolarHBondContact O-OG1 3.44Å; S202-T205 PolarHBondContact O-N 3.17Å; W203-T205 VanDerWaalsContact C-N 3.34Å; W203-T205 PolarHBondContact O-N 3.04Å; T205-F207 VanDerWaalsContact C-N 3.31Å; T205-F207 PolarHBondContact O-N 3.32Å; T205-C208 PolarHBondContact O-N 3.4Å; T205-V209 HydrophobicContact CG2-CG2 4.5Å; T205-V209 WeakPolarHBondContact O-CG2 3.3Å; T205-V209 PolarHBondContact O-N 3.04Å
206	S	98.3	Very high	96.2	Very high	1 Å²	1	53 Å²	53	1%	0.007	30%	0.302	C	S	.	.	H	α-helix	trans	-62	-40.2	178.8	-55.6	0	0	0	0	111.5	L163 I166 E167 S202 W203 V209 A210	L163-S206 VanDerWaalsContact CD1-C 3.49Å; I166-S206 WeakPolarHBondContact CG2-OG 3.36Å; E167-S206 WeakPolarHBondContact CA-OG 3.41Å; E167-S206 PolarHBondContact N-OG 3.45Å; S202-S206 VanDerWaalsContact O-CB 3.27Å; S202-S206 WeakPolarHBondContact O-CB 3.36Å; S202-S206 PolarHBondContact O-N 2.92Å; S202-S206 PolarHBondContact O-OG 3.24Å; W203-S206 PolarHBondContact O-N 3.33Å; S206-V209 PolarHBondContact O-N 3Å; S206-A210 VanDerWaalsContact O-CB 3.3Å; S206-A210 WeakPolarHBondContact O-CB 3.41Å; S206-A210 PolarHBondContact O-N 3.33Å
207	F	97.9	Very high	95.6	Very high	96 Å²	96	52.2 Å²	52.2	42%	0.421	30%	0.304	S	S	.	.	H	α-helix	trans	-63.4	-50.8	174.6	-178.9	-98	0	0	0	111.1	M159 L163 W203 A204 T205 V209 A210 F211	M159-F207 HydrophobicContact CE-CD2 4.36Å; L163-F207 HydrophobicContact CD1-CB 4.12Å; L163-F207 HydrophobicContact CD2-CD2 4.43Å; W203-F207 WeakPolarHBondContact O-CB 3.37Å; W203-F207 PolarHBondContact O-N 3.34Å; A204-F207 PolarHBondContact O-N 3.02Å; T205-F207 VanDerWaalsContact C-N 3.31Å; T205-F207 PolarHBondContact O-N 3.32Å; F207-V209 VanDerWaalsContact C-N 3.27Å; F207-V209 PolarHBondContact O-N 2.86Å; F207-A210 PolarHBondContact O-N 3.43Å; F207-F211 HydrophobicContact CE1-CB 4.3Å; F207-F211 AromaticContact CE1-CD2 3.97Å; F207-F211 HydrophobicContact CE1-CD2 3.97Å; F207-F211 HydrophobicContact CE1-CG 4.17Å; F207-F211 HydrophobicContact CE2-CD2 4.09Å; F207-F211 HydrophobicContact CZ-CB 4.41Å; F207-F211 AromaticContact CZ-CD2 3.48Å; F207-F211 HydrophobicContact CZ-CD2 3.48Å; F207-F211 VanDerWaalsContact CZ-CD2 3.48Å; F207-F211 AromaticContact CZ-CE2 3.97Å; F207-F211 HydrophobicContact CZ-CE2 3.97Å; F207-F211 HydrophobicContact CZ-CG 4.13Å; F207-F211 WeakPolarHBondContact O-CB 3.49Å; F207-F211 PolarHBondContact O-N 2.85Å
208	C	97.4	Very high	95	Very high	90 Å²	90	49.3 Å²	49.3	61%	0.608	29%	0.287	S	S	*	.	H	α-helix	trans	-57.6	-39.6	178.7	-70.9	0	0	0	0	112.7	A204 T205 P212	A204-C208 WeakPolarHBondContact O-CB 3.28Å; A204-C208 PolarHBondContact O-N 3.42Å; A204-C208 PolarHBondContact O-SG 2.97Å; T205-C208 PolarHBondContact O-N 3.4Å; C208-P212 WeakPolarHBondContact O-CD 3.24Å
209	V	96.2	Very high	94.1	Very high	23 Å²	23	50.1 Å²	50.1	14%	0.139	29%	0.291	C	S	.	.	H	α-helix	trans	-71.8	-39.5	178.7	174.8	0	0	0	0	111.7	I166 T205 S206 F207 P212 Y242 I246 I249	I166-V209 HydrophobicContact CD1-CB 4.1Å; I166-V209 HydrophobicContact CD1-CG1 3.63Å; T205-V209 HydrophobicContact CG2-CG2 4.5Å; T205-V209 WeakPolarHBondContact O-CG2 3.3Å; T205-V209 PolarHBondContact O-N 3.04Å; S206-V209 PolarHBondContact O-N 3Å; F207-V209 VanDerWaalsContact C-N 3.27Å; F207-V209 PolarHBondContact O-N 2.86Å; V209-P212 WeakPolarHBondContact O-CD 3.37Å; V209-Y242 PolarHBondContact O-OH 3.44Å; V209-I246 HydrophobicContact CG1-CG1 4.31Å; V209-I249 HydrophobicContact CG1-CD1 4.34Å; V209-I249 HydrophobicContact CG2-CD1 4.13Å
210	A	96.6	Very high	93.3	Very high	0 Å²	0	49.3 Å²	49.3	0%	0	29%	0.287	C	S	.	.	H	α-helix	trans	-84.4	-26.3	-176.4	0	0	0	0	0	114	M159 W162 L163 S206 F207 L213	M159-A210 HydrophobicContact CG-CB 4.18Å; M159-A210 WeakPolarHBondContact CG-O 3.35Å; W162-A210 HydrophobicContact CB-CB 4.21Å; L163-A210 HydrophobicContact CB-CB 4.04Å; S206-A210 VanDerWaalsContact O-CB 3.3Å; S206-A210 WeakPolarHBondContact O-CB 3.41Å; S206-A210 PolarHBondContact O-N 3.33Å; F207-A210 PolarHBondContact O-N 3.43Å; A210-L213 WeakPolarHBondContact O-CB 3.39Å; A210-L213 PolarHBondContact O-N 3.16Å; A210-L213 VanDerWaalsContact O-N 3.16Å
211	F	95.9	Very high	92	Very high	90 Å²	90	50.8 Å²	50.8	40%	0.395	28%	0.283	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.2	-37.5	-174.9	-177	-113.1	0	0	0	115.5	F207 L213 A214 I215	F207-F211 HydrophobicContact CE1-CB 4.3Å; F207-F211 AromaticContact CE1-CD2 3.97Å; F207-F211 HydrophobicContact CE1-CD2 3.97Å; F207-F211 HydrophobicContact CE1-CG 4.17Å; F207-F211 HydrophobicContact CE2-CD2 4.09Å; F207-F211 HydrophobicContact CZ-CB 4.41Å; F207-F211 AromaticContact CZ-CD2 3.48Å; F207-F211 HydrophobicContact CZ-CD2 3.48Å; F207-F211 VanDerWaalsContact CZ-CD2 3.48Å; F207-F211 AromaticContact CZ-CE2 3.97Å; F207-F211 HydrophobicContact CZ-CE2 3.97Å; F207-F211 HydrophobicContact CZ-CG 4.13Å; F207-F211 WeakPolarHBondContact O-CB 3.49Å; F207-F211 PolarHBondContact O-N 2.85Å; F211-L213 PolarHBondContact O-N 2.74Å; F211-A214 HydrophobicContact CD2-CB 4.48Å; F211-A214 WeakPolarHBondContact O-CB 3Å; F211-A214 PolarHBondContact O-N 2.9Å; F211-I215 HydrophobicContact CD1-CD1 3.98Å; F211-I215 HydrophobicContact CD1-CG1 4.45Å; F211-I215 HydrophobicContact CE1-CD1 3.58Å; F211-I215 HydrophobicContact CE1-CG1 4.04Å; F211-I215 HydrophobicContact CZ-CD1 4.23Å; F211-I215 HydrophobicContact CZ-CG1 4.23Å
212	P	94.9	Very high	90.6	Very high	39 Å²	39	50.2 Å²	50.2	25%	0.253	28%	0.277	S	S	.	.	H	α-helix	trans	-53.5	-29.9	177.5	-28.6	37.1	0	0	0	114	C208 V209 A214 I215 G216 N217 Y242	C208-P212 WeakPolarHBondContact O-CD 3.24Å; V209-P212 WeakPolarHBondContact O-CD 3.37Å; P212-A214 VanDerWaalsContact C-N 3.34Å; P212-A214 PolarHBondContact O-N 3.13Å; P212-I215 PolarHBondContact O-N 2.92Å; P212-G216 PolarHBondContact O-N 2.8Å; P212-G216 VanDerWaalsContact O-N 3.15Å; P212-N217 CarbonylContact C-O 3.3Å; P212-N217 VanDerWaalsContact C-O 3.3Å; P212-N217 WeakPolarHBondContact CB-O 3.39Å; P212-N217 PolarHBondContact O-N 2.83Å; P212-N217 VanDerWaalsContact O-O 3.08Å; P212-Y242 HydrophobicContact CB-CE2 4.02Å; P212-Y242 HydrophobicContact CG-CE2 4.08Å
213	L	92.9	Very high	89.1	Confident	0 Å²	0	50.2 Å²	50.2	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-63.8	-36.3	175.5	-67.4	168.8	0	0	0	113.2	R155 M159 W162 A210 F211 I215 G216 P218 L220 F231 Y242 I246	R155-L213 VanDerWaalsContact CB-O 3.29Å; R155-L213 WeakPolarHBondContact CB-O 3.32Å; M159-L213 HydrophobicContact CB-CB 3.97Å; W162-L213 HydrophobicContact CB-CD1 4.3Å; W162-L213 VanDerWaalsContact CD1-CD1 3.44Å; W162-L213 HydrophobicContact CG-CD1 4.13Å; A210-L213 WeakPolarHBondContact O-CB 3.39Å; A210-L213 PolarHBondContact O-N 3.16Å; A210-L213 VanDerWaalsContact O-N 3.16Å; F211-L213 PolarHBondContact O-N 2.74Å; L213-I215 VanDerWaalsContact C-N 3.32Å; L213-I215 PolarHBondContact O-N 3.41Å; L213-G216 PolarHBondContact O-N 3.46Å; L213-G216 VanDerWaalsContact O-N 3.1Å; L213-P218 HydrophobicContact CD2-CG 4.41Å; L213-L220 HydrophobicContact CD2-CD1 4.02Å; L213-L220 HydrophobicContact CD2-CD2 4.37Å; L213-L220 HydrophobicContact CD2-CG 4.22Å; L213-F231 HydrophobicContact CD2-CE1 3.91Å; L213-F231 HydrophobicContact CD2-CZ 4.49Å; L213-Y242 HydrophobicContact CD1-CE1 4.24Å; L213-Y242 HydrophobicContact CD2-CE1 3.73Å; L213-Y242 HydrophobicContact CG-CE1 3.9Å; L213-Y242 WeakPolarHBondContact CG-OH 3.21Å; L213-I246 HydrophobicContact CD1-CD1 4.48Å
214	A	92.9	Very high	87.4	Confident	21 Å²	21	52 Å²	52	17%	0.174	30%	0.298	C	S	.	.	H	α-helix	trans	-66.7	-36.4	179.1	0	0	0	0	0	111.6	M159 F211 P212 G216	M159-A214 HydrophobicContact CB-CB 4.1Å; M159-A214 HydrophobicContact CG-CB 3.99Å; M159-A214 HydrophobicContact SD-CB 4.26Å; F211-A214 HydrophobicContact CD2-CB 4.48Å; F211-A214 WeakPolarHBondContact O-CB 3Å; F211-A214 PolarHBondContact O-N 2.9Å; P212-A214 VanDerWaalsContact C-N 3.34Å; P212-A214 PolarHBondContact O-N 3.13Å; A214-G216 PolarHBondContact O-N 3.1Å
215	I	91.6	Very high	85.7	Confident	112 Å²	112	54.7 Å²	54.7	57%	0.574	30%	0.296	S	S	*	.	H	α-helix	trans	-70	-26.1	174.7	-51.4	175.5	0	0	0	110.7	F211 P212 L213	F211-I215 HydrophobicContact CD1-CD1 3.98Å; F211-I215 HydrophobicContact CD1-CG1 4.45Å; F211-I215 HydrophobicContact CE1-CD1 3.58Å; F211-I215 HydrophobicContact CE1-CG1 4.04Å; F211-I215 HydrophobicContact CZ-CD1 4.23Å; F211-I215 HydrophobicContact CZ-CG1 4.23Å; P212-I215 PolarHBondContact O-N 2.92Å; L213-I215 VanDerWaalsContact C-N 3.32Å; L213-I215 PolarHBondContact O-N 3.41Å
216	G	84.9	Confident	84.2	Confident	10 Å²	10	51.3 Å²	51.3	10%	0.103	28%	0.275	C	S	.	.	T	Hydrogen-bonded Turn	trans	91.4	27.2	-176.4	0	0	0	0	0	113.4	P212 L213 A214 P218 D219	P212-G216 PolarHBondContact O-N 2.8Å; P212-G216 VanDerWaalsContact O-N 3.15Å; L213-G216 PolarHBondContact O-N 3.46Å; L213-G216 VanDerWaalsContact O-N 3.1Å; A214-G216 PolarHBondContact O-N 3.1Å; G216-P218 CarbonylContact C-O 3.3Å; G216-P218 VanDerWaalsContact C-O 3.3Å; G216-P218 CarbonylContact O-C 3.25Å; G216-P218 VanDerWaalsContact O-C 3.25Å; G216-D219 WeakPolarHBondContact O-CA 3.39Å; G216-D219 PolarHBondContact O-N 3.4Å
217	N	85.3	Confident	82.6	Confident	117 Å²	117	51.5 Å²	51.5	63%	0.626	28%	0.277	S	S	*	.	S	Bend	trans	-123.7	101.7	172.1	-168.2	-12.5	0	0	0	109.2	P212	P212-N217 CarbonylContact C-O 3.3Å; P212-N217 VanDerWaalsContact C-O 3.3Å; P212-N217 WeakPolarHBondContact CB-O 3.39Å; P212-N217 PolarHBondContact O-N 2.83Å; P212-N217 VanDerWaalsContact O-O 3.08Å
218	P	84.3	Confident	81.6	Confident	5 Å²	5	47.2 Å²	47.2	3%	0.032	26%	0.258	C	S	.	.	S	Bend	cis	-77.8	159.3	9.4	29.9	-35	0	0	0	114.8	L213 G216 L220 Y239 Y242	L213-P218 HydrophobicContact CD2-CG 4.41Å; G216-P218 CarbonylContact C-O 3.3Å; G216-P218 VanDerWaalsContact C-O 3.3Å; G216-P218 CarbonylContact O-C 3.25Å; G216-P218 VanDerWaalsContact O-C 3.25Å; P218-L220 PolarHBondContact O-N 3.42Å; P218-Y239 HydrophobicContact CB-CD1 3.49Å; P218-Y239 VanDerWaalsContact CB-CD1 3.49Å; P218-Y239 HydrophobicContact CB-CD2 3.65Å; P218-Y239 HydrophobicContact CB-CE1 3.99Å; P218-Y239 HydrophobicContact CB-CE2 4.15Å; P218-Y239 HydrophobicContact CB-CG 3.3Å; P218-Y239 HydrophobicContact CG-CD1 4.32Å; P218-Y239 HydrophobicContact CG-CD2 3.65Å; P218-Y239 HydrophobicContact CG-CE2 3.93Å; P218-Y239 HydrophobicContact CG-CG 3.88Å; P218-Y242 VanDerWaalsContact CD-CD1 3.5Å; P218-Y242 HydrophobicContact CG-CD1 3.62Å; P218-Y242 HydrophobicContact CG-CE1 4.19Å; P218-Y242 HydrophobicContact CG-CG 4.16Å
219	D	79.6	Confident	80.9	Confident	87 Å²	87	43.1 Å²	43.1	47%	0.465	23%	0.23	S	C	.	.			trans	-72.8	110.7	178.8	-120.8	-28	0	0	0	110.5	K151 R155 G216 Y239	K151-D219 IonicContact NZ-OD1 2.92Å; K151-D219 PolarHBondContact NZ-OD1 3.48Å; R155-D219 IonicContact CZ-OD1 3.67Å; R155-D219 IonicContact NE-OD1 3.92Å; R155-D219 IonicContact NH2-OD1 2.69Å; R155-D219 PolarHBondContact NH2-OD1 3.05Å; G216-D219 WeakPolarHBondContact O-CA 3.39Å; G216-D219 PolarHBondContact O-N 3.4Å; D219-Y239 WeakPolarHBondContact O-CE1 3.29Å
220	L	81.4	Confident	80.4	Confident	6 Å²	6	42.3 Å²	42.3	3%	0.031	23%	0.226	C	C	.	.			trans	-76.5	129.8	176.3	-72	165.7	0	0	0	110.7	R155 A158 L213 P218 C229 F231	R155-L220 HydrophobicContact CG-CD1 4.47Å; A158-L220 HydrophobicContact CB-CD1 3.49Å; A158-L220 VanDerWaalsContact CB-CD1 3.49Å; L213-L220 HydrophobicContact CD2-CD1 4.02Å; L213-L220 HydrophobicContact CD2-CD2 4.37Å; L213-L220 HydrophobicContact CD2-CG 4.22Å; P218-L220 PolarHBondContact O-N 3.42Å; L220-C229 HydrophobicContact CD1-CB 4.37Å; L220-F231 HydrophobicContact CD2-CD1 3.81Å; L220-F231 HydrophobicContact CD2-CE1 4.05Å
221	Q	71.9	Confident	80	Confident	91 Å²	91	42.5 Å²	42.5	43%	0.425	23%	0.226	S	C	.	.			trans	-80.3	139	168.3	-62.7	-168	10.9	0	0	109.4	P223	Q221-P223 WeakPolarHBondContact O-CD 3.49Å
222	I	69	Low	79.6	Confident	71 Å²	71	38.3 Å²	38.3	36%	0.364	21%	0.208	S	C	.	.			trans	-89.6	99.7	171.2	-54.8	172.1	0	0	0	106.4	W147 K151 C154	W147-I222 HydrophobicContact CB-CG2 3.82Å; W147-I222 HydrophobicContact CG-CG2 4.22Å; K151-I222 HydrophobicContact CB-CD1 4.05Å; K151-I222 HydrophobicContact CG-CD1 4.34Å; C154-I222 HydrophobicContact CB-CG1 4.39Å
223	P	66.9	Low	79.4	Confident	10 Å²	10	39.2 Å²	39.2	7%	0.065	21%	0.207	C	C	.	.			trans	-67.8	145.2	173.8	29.7	-37.5	0	0	0	110.6	Q221 R225 A226 V230 F350	Q221-P223 WeakPolarHBondContact O-CD 3.49Å; P223-R225 PolarHBondContact O-N 2.99Å; P223-A226 HydrophobicContact CB-CB 4.21Å; P223-A226 HydrophobicContact CG-CB 3.28Å; P223-V230 HydrophobicContact CG-CG2 4.24Å; P223-F350 HydrophobicContact CB-CD1 3.57Å; P223-F350 HydrophobicContact CB-CE1 2.97Å; P223-F350 HydrophobicContact CB-CE2 4.26Å; P223-F350 HydrophobicContact CB-CG 4.44Å; P223-F350 HydrophobicContact CB-CZ 3.37Å; P223-F350 HydrophobicContact CG-CD1 4.09Å; P223-F350 HydrophobicContact CG-CE1 3.75Å
224	S	60.8	Low	79.3	Confident	93 Å²	93	40.1 Å²	40.1	65%	0.65	21%	0.212	S	C	*	.	T	Hydrogen-bonded Turn	trans	-66.7	-4	-176.3	33	0	0	0	0	114.7
225	R	64.1	Low	79.2	Confident	112 Å²	112	44.1 Å²	44.1	42%	0.423	24%	0.235	S	C	.	.	T	Hydrogen-bonded Turn	trans	-145.9	7.4	-174.5	-63.7	-174.6	-176.2	164	2.6	116.2	P223 F350	P223-R225 PolarHBondContact O-N 2.99Å; R225-F350 HydrophobicContact CB-CB 3.87Å; R225-F350 HydrophobicContact CB-CD2 4.34Å; R225-F350 HydrophobicContact CB-CG 4.19Å
226	A	65.6	Low	79.3	Confident	3 Å²	3	43.1 Å²	43.1	3%	0.025	23%	0.231	C	C	.	.			trans	-89.7	139.9	178.9	0	0	0	0	0	111.4	T141 P223 Q228 V230 F350	T141-A226 VanDerWaalsContact CG2-O 3.26Å; T141-A226 WeakPolarHBondContact CG2-O 3.4Å; P223-A226 HydrophobicContact CB-CB 4.21Å; P223-A226 HydrophobicContact CG-CB 3.28Å; A226-Q228 VanDerWaalsContact CB-O 3.32Å; A226-Q228 WeakPolarHBondContact CB-O 3Å; A226-Q228 PolarHBondContact O-N 2.88Å; A226-V230 HydrophobicContact CB-CG2 4.3Å; A226-F350 HydrophobicContact CB-CD1 4.11Å
227	P	64.6	Low	79.7	Confident	5 Å²	5	47.3 Å²	47.3	3%	0.032	26%	0.256	C	S	.	.	S	Bend	trans	-64.1	-18.8	179	28.6	-40.6	0	0	0	113.4	A138 T354 L357	A138-P227 WeakPolarHBondContact CA-O 3.37Å; A138-P227 HydrophobicContact CB-CB 4.23Å; P227-T354 WeakPolarHBondContact CD-OG1 3.41Å; P227-T354 HydrophobicContact CG-CG2 3.94Å; P227-L357 HydrophobicContact CB-CD2 4.24Å; P227-L357 HydrophobicContact CG-CD2 3.54Å
228	Q	76.9	Confident	80	Confident	6 Å²	6	43.8 Å²	43.8	3%	0.028	25%	0.247	C	C	.	.	S	Bend	trans	-147.7	169.6	175	75.2	179.6	-6	0	0	109.5	A226 V230 L357 Y361	A226-Q228 VanDerWaalsContact CB-O 3.32Å; A226-Q228 WeakPolarHBondContact CB-O 3Å; A226-Q228 PolarHBondContact O-N 2.88Å; Q228-V230 HydrophobicContact CG-CG1 3.93Å; Q228-V230 PolarHBondContact O-N 2.9Å; Q228-L357 HydrophobicContact CB-CD2 4.11Å; Q228-L357 HydrophobicContact CG-CD2 3.48Å; Q228-L357 VanDerWaalsContact CG-CD2 3.48Å; Q228-Y361 PolarHBondContact OE1-OH 3.46Å
229	C	83.6	Confident	80.4	Confident	5 Å²	5	44.2 Å²	44.2	3%	0.034	25%	0.248	C	C	.	.			trans	-71.9	119.8	171.8	-63.7	0	0	0	0	111	C154 A158 L220	C154-C229 WeakPolarHBondContact CA-SG 3.41Å; C154-C229 HydrophobicContact CB-CB 4.22Å; C154-C229 WeakPolarHBondContact CB-SG 3.46Å; C154-C229 WeakPolarHBondContact SG-CB 3.32Å; C154-C229 CovalentContact SG-SG 1.99Å; C154-C229 PolarHBondContact SG-SG 2.84Å; A158-C229 HydrophobicContact CB-CB 4.27Å; L220-C229 HydrophobicContact CD1-CB 4.37Å
230	V	84.5	Confident	81.1	Confident	6 Å²	6	42.3 Å²	42.3	4%	0.036	24%	0.237	C	C	.	.			trans	-117.2	162.6	-177.7	-65.9	0	0	0	0	110.3	P223 A226 Q228	P223-V230 HydrophobicContact CG-CG2 4.24Å; A226-V230 HydrophobicContact CB-CG2 4.3Å; Q228-V230 HydrophobicContact CG-CG1 3.93Å; Q228-V230 PolarHBondContact O-N 2.9Å
231	F	89.3	Confident	81.8	Confident	4 Å²	4	44.8 Å²	44.8	2%	0.018	26%	0.258	C	S	.	.			trans	-66.5	136.7	172.3	-61.2	-50.2	0	0	0	110.9	W162 L213 L220 Y239 Y242 V243 I246	W162-F231 AromaticContact CE2-CE2 3.46Å; W162-F231 VanDerWaalsContact CE2-CE2 3.46Å; W162-F231 AromaticContact CE2-CZ 3.79Å; W162-F231 HydrophobicContact CH2-CE2 4.24Å; W162-F231 AromaticContact CZ2-CD2 3.96Å; W162-F231 HydrophobicContact CZ2-CD2 3.96Å; W162-F231 AromaticContact CZ2-CE2 3.31Å; W162-F231 HydrophobicContact CZ2-CE2 3.31Å; W162-F231 HydrophobicContact CZ2-CZ 4.12Å; W162-F231 AromaticContact NE1-CE2 3.48Å; W162-F231 AromaticContact NE1-CZ 3.36Å; L213-F231 HydrophobicContact CD2-CE1 3.91Å; L213-F231 HydrophobicContact CD2-CZ 4.49Å; L220-F231 HydrophobicContact CD2-CD1 3.81Å; L220-F231 HydrophobicContact CD2-CE1 4.05Å; F231-Y239 WeakPolarHBondContact CA-OH 3.43Å; F231-Y239 HydrophobicContact CB-CE2 4.35Å; F231-Y239 AromaticContact CD1-CE2 3.74Å; F231-Y239 HydrophobicContact CD1-CE2 3.74Å; F231-Y239 HydrophobicContact CE1-CE2 4.47Å; F231-Y239 HydrophobicContact CG-CE2 4.33Å; F231-Y242 HydrophobicContact CE1-CD1 4.44Å; F231-Y242 HydrophobicContact CE1-CE1 4.24Å; F231-Y242 HydrophobicContact CZ-CD1 4.5Å; F231-Y242 HydrophobicContact CZ-CE1 4.15Å; F231-V243 HydrophobicContact CB-CG2 4.18Å; F231-V243 HydrophobicContact CD1-CG2 3.97Å; F231-V243 HydrophobicContact CD2-CG1 4.25Å; F231-V243 HydrophobicContact CD2-CG2 3.95Å; F231-V243 HydrophobicContact CE1-CG2 4.35Å; F231-V243 HydrophobicContact CE2-CG2 4.32Å; F231-V243 HydrophobicContact CG-CG2 3.77Å; F231-I246 HydrophobicContact CE2-CD1 4.25Å; F231-I246 HydrophobicContact CE2-CG2 4.29Å; F231-I246 HydrophobicContact CZ-CD1 3.7Å
232	G	87.6	Confident	82.9	Confident	1 Å²	1	41.6 Å²	41.6	1%	0.01	24%	0.242	C	C	.	.			trans	-113.9	176.6	176.9	0	0	0	0	0	113.1	Y239	G232-Y239 PolarHBondContact N-OH 3.04Å; G232-Y239 VanDerWaalsContact N-OH 3.08Å
233	Y	89.9	Confident	84.1	Confident	58 Å²	58	38.2 Å²	38.2	23%	0.227	23%	0.225	C	C	.	.			trans	-61.5	136.1	174	170.7	-104	0	0	0	111.4	T235 A337 T338 K341	Y233-T235 HydrophobicContact CE1-CG2 4.28Å; Y233-T235 VanDerWaalsContact OH-CG2 3.27Å; Y233-T235 WeakPolarHBondContact OH-CG2 3.48Å; Y233-A337 VanDerWaalsContact CA-O 3.31Å; Y233-A337 WeakPolarHBondContact CA-O 3.49Å; Y233-A337 PolarHBondContact N-O 3.38Å; Y233-T338 WeakPolarHBondContact CD2-O 3.42Å; Y233-K341 HydrophobicContact CD1-CB 3.99Å; Y233-K341 HydrophobicContact CD1-CD 4.41Å; Y233-K341 HydrophobicContact CD1-CG 3.9Å; Y233-K341 HydrophobicContact CD2-CB 3.91Å; Y233-K341 VanDerWaalsContact CD2-N 3.31Å; Y233-K341 HydrophobicContact CE1-CB 3.8Å; Y233-K341 HydrophobicContact CE1-CD 3.91Å; Y233-K341 HydrophobicContact CE1-CG 3.82Å; Y233-K341 HydrophobicContact CE2-CB 3.73Å; Y233-K341 HydrophobicContact CG-CB 4.02Å; Y233-K341 HydrophobicContact CG-CG 4.33Å
234	T	90.3	Very high	85.5	Confident	19 Å²	19	41 Å²	41	12%	0.117	24%	0.239	C	C	.	.			trans	-151.5	145.7	178.7	-172.5	0	0	0	0	111.7	N236 Y239 Q240 T338	T234-N236 PolarHBondContact OG1-N 3.37Å; T234-N236 VanDerWaalsContact OG1-N 3.17Å; T234-Y239 HydrophobicContact CG2-CD1 3.66Å; T234-Y239 HydrophobicContact CG2-CD2 3.91Å; T234-Y239 HydrophobicContact CG2-CE1 4.23Å; T234-Y239 HydrophobicContact CG2-CE2 4.43Å; T234-Y239 HydrophobicContact CG2-CG 3.47Å; T234-Y239 VanDerWaalsContact CG2-CG 3.47Å; T234-Q240 HydrophobicContact CG2-CG 3.88Å; T234-Q240 PolarHBondContact O-NE2 2.85Å; T234-T338 HydrophobicContact CG2-CG2 3.83Å; T234-T338 PolarHBondContact N-O 3.08Å
235	T	91.4	Very high	87.2	Confident	106 Å²	106	40.4 Å²	40.4	65%	0.65	23%	0.228	S	C	*	.			trans	-96.9	-5.7	170.2	52.8	0	0	0	0	112.4	Y233 P237	Y233-T235 HydrophobicContact CE1-CG2 4.28Å; Y233-T235 VanDerWaalsContact OH-CG2 3.27Å; Y233-T235 WeakPolarHBondContact OH-CG2 3.48Å; T235-P237 WeakPolarHBondContact O-CD 3.23Å
236	N	93.3	Very high	88.6	Confident	90 Å²	90	35.1 Å²	35.1	48%	0.481	21%	0.208	S	C	.	.			trans	-74.4	120.1	-179.1	-175.8	-44	0	0	0	110.1	T234 G238 Y239 Q240	T234-N236 PolarHBondContact OG1-N 3.37Å; T234-N236 VanDerWaalsContact OG1-N 3.17Å; N236-G238 VanDerWaalsContact C-N 3.29Å; N236-G238 PolarHBondContact O-N 3.21Å; N236-G238 WeakPolarHBondContact OD1-CA 2.99Å; N236-G238 PolarHBondContact OD1-N 2.99Å; N236-Y239 PolarHBondContact O-N 3.33Å; N236-Y239 PolarHBondContact OD1-N 3.04Å; N236-Q240 WeakPolarHBondContact O-CG 3.14Å; N236-Q240 PolarHBondContact O-N 3.45Å
237	P	92.8	Very high	90.1	Very high	98 Å²	98	35.1 Å²	35.1	64%	0.636	21%	0.208	S	C	*	.	H	α-helix	trans	-64.4	-31.2	-177.1	25.6	-34.3	0	0	0	113.1	T235 Q240 A241	T235-P237 WeakPolarHBondContact O-CD 3.23Å; P237-Q240 PolarHBondContact O-N 3.36Å; P237-A241 VanDerWaalsContact O-CB 3.28Å; P237-A241 WeakPolarHBondContact O-CB 3.16Å; P237-A241 PolarHBondContact O-N 3.46Å
238	G	92.8	Very high	91.6	Very high	43 Å²	43	38.2 Å²	38.2	44%	0.443	22%	0.224	S	C	.	.	H	α-helix	trans	-67.6	-40.5	176.3	0	0	0	0	0	112.6	N236 Y242	N236-G238 VanDerWaalsContact C-N 3.29Å; N236-G238 PolarHBondContact O-N 3.21Å; N236-G238 WeakPolarHBondContact OD1-CA 2.99Å; N236-G238 PolarHBondContact OD1-N 2.99Å; G238-Y242 WeakPolarHBondContact O-CB 3.28Å; G238-Y242 PolarHBondContact O-N 3.12Å
239	Y	92.9	Very high	92.5	Very high	14 Å²	14	40.4 Å²	40.4	6%	0.055	24%	0.235	C	C	.	.	H	α-helix	trans	-63.1	-51.6	172.1	-169.6	159.1	0	0	0	109.2	P218 D219 F231 G232 T234 N236 A241 Y242 V243	P218-Y239 HydrophobicContact CB-CD1 3.49Å; P218-Y239 VanDerWaalsContact CB-CD1 3.49Å; P218-Y239 HydrophobicContact CB-CD2 3.65Å; P218-Y239 HydrophobicContact CB-CE1 3.99Å; P218-Y239 HydrophobicContact CB-CE2 4.15Å; P218-Y239 HydrophobicContact CB-CG 3.3Å; P218-Y239 HydrophobicContact CG-CD1 4.32Å; P218-Y239 HydrophobicContact CG-CD2 3.65Å; P218-Y239 HydrophobicContact CG-CE2 3.93Å; P218-Y239 HydrophobicContact CG-CG 3.88Å; D219-Y239 WeakPolarHBondContact O-CE1 3.29Å; F231-Y239 WeakPolarHBondContact CA-OH 3.43Å; F231-Y239 HydrophobicContact CB-CE2 4.35Å; F231-Y239 AromaticContact CD1-CE2 3.74Å; F231-Y239 HydrophobicContact CD1-CE2 3.74Å; F231-Y239 HydrophobicContact CE1-CE2 4.47Å; F231-Y239 HydrophobicContact CG-CE2 4.33Å; G232-Y239 PolarHBondContact N-OH 3.04Å; G232-Y239 VanDerWaalsContact N-OH 3.08Å; T234-Y239 HydrophobicContact CG2-CD1 3.66Å; T234-Y239 HydrophobicContact CG2-CD2 3.91Å; T234-Y239 HydrophobicContact CG2-CE1 4.23Å; T234-Y239 HydrophobicContact CG2-CE2 4.43Å; T234-Y239 HydrophobicContact CG2-CG 3.47Å; T234-Y239 VanDerWaalsContact CG2-CG 3.47Å; N236-Y239 PolarHBondContact O-N 3.33Å; N236-Y239 PolarHBondContact OD1-N 3.04Å; Y239-A241 VanDerWaalsContact C-N 3.29Å; Y239-A241 PolarHBondContact O-N 3.32Å; Y239-Y242 WeakPolarHBondContact O-CA 3.44Å; Y239-Y242 WeakPolarHBondContact O-CB 3.23Å; Y239-Y242 PolarHBondContact O-N 2.88Å; Y239-V243 HydrophobicContact CD2-CG2 3.62Å; Y239-V243 HydrophobicContact CE2-CG2 3.42Å; Y239-V243 VanDerWaalsContact CE2-CG2 3.42Å; Y239-V243 PolarHBondContact O-N 2.97Å
240	Q	94.2	Very high	93	Very high	47 Å²	47	40.1 Å²	40.1	22%	0.22	23%	0.233	C	C	.	.	H	α-helix	trans	-55.5	-44.7	179.3	-68.2	178.3	-13.5	0	0	112.3	T234 N236 P237 Y242 V243 I244 T338 F339	T234-Q240 HydrophobicContact CG2-CG 3.88Å; T234-Q240 PolarHBondContact O-NE2 2.85Å; N236-Q240 WeakPolarHBondContact O-CG 3.14Å; N236-Q240 PolarHBondContact O-N 3.45Å; P237-Q240 PolarHBondContact O-N 3.36Å; Q240-Y242 VanDerWaalsContact C-N 3.33Å; Q240-Y242 PolarHBondContact O-N 2.81Å; Q240-V243 PolarHBondContact O-N 3.26Å; Q240-I244 WeakPolarHBondContact O-CG1 3.48Å; Q240-I244 PolarHBondContact O-N 3.23Å; Q240-T338 HydrophobicContact CG-CG2 4.14Å; Q240-F339 HydrophobicContact CB-CE1 3.93Å; Q240-F339 HydrophobicContact CB-CZ 4.02Å; Q240-F339 HydrophobicContact CG-CD1 4.47Å; Q240-F339 HydrophobicContact CG-CE1 3.84Å; Q240-F339 HydrophobicContact CG-CZ 4.27Å
241	A	95.1	Very high	93.5	Very high	58 Å²	58	40.5 Å²	40.5	48%	0.479	23%	0.234	S	C	.	.	H	α-helix	trans	-60.1	-41.3	175.5	0	0	0	0	0	112.2	P237 Y239 I244 L245	P237-A241 VanDerWaalsContact O-CB 3.28Å; P237-A241 WeakPolarHBondContact O-CB 3.16Å; P237-A241 PolarHBondContact O-N 3.46Å; Y239-A241 VanDerWaalsContact C-N 3.29Å; Y239-A241 PolarHBondContact O-N 3.32Å; A241-I244 PolarHBondContact O-N 2.9Å; A241-L245 WeakPolarHBondContact O-CB 3.16Å; A241-L245 PolarHBondContact O-N 3.37Å
242	Y	95.2	Very high	93.9	Very high	24 Å²	24	43.6 Å²	43.6	9%	0.094	25%	0.248	C	C	.	.	H	α-helix	trans	-64.2	-42.4	176.6	-176	-97.9	0	0	0	112.8	V209 P212 L213 P218 F231 G238 Y239 Q240 L245 I246	V209-Y242 PolarHBondContact O-OH 3.44Å; P212-Y242 HydrophobicContact CB-CE2 4.02Å; P212-Y242 HydrophobicContact CG-CE2 4.08Å; L213-Y242 HydrophobicContact CD1-CE1 4.24Å; L213-Y242 HydrophobicContact CD2-CE1 3.73Å; L213-Y242 HydrophobicContact CG-CE1 3.9Å; L213-Y242 WeakPolarHBondContact CG-OH 3.21Å; P218-Y242 VanDerWaalsContact CD-CD1 3.5Å; P218-Y242 HydrophobicContact CG-CD1 3.62Å; P218-Y242 HydrophobicContact CG-CE1 4.19Å; P218-Y242 HydrophobicContact CG-CG 4.16Å; F231-Y242 HydrophobicContact CE1-CD1 4.44Å; F231-Y242 HydrophobicContact CE1-CE1 4.24Å; F231-Y242 HydrophobicContact CZ-CD1 4.5Å; F231-Y242 HydrophobicContact CZ-CE1 4.15Å; G238-Y242 WeakPolarHBondContact O-CB 3.28Å; G238-Y242 PolarHBondContact O-N 3.12Å; Y239-Y242 WeakPolarHBondContact O-CA 3.44Å; Y239-Y242 WeakPolarHBondContact O-CB 3.23Å; Y239-Y242 PolarHBondContact O-N 2.88Å; Q240-Y242 VanDerWaalsContact C-N 3.33Å; Q240-Y242 PolarHBondContact O-N 2.81Å; Y242-L245 WeakPolarHBondContact O-CB 3.14Å; Y242-L245 PolarHBondContact O-N 3.21Å; Y242-I246 HydrophobicContact CD1-CD1 4.01Å; Y242-I246 HydrophobicContact CE1-CD1 3.22Å; Y242-I246 HydrophobicContact CE1-CG1 4.08Å; Y242-I246 HydrophobicContact CE2-CD1 4.37Å; Y242-I246 VanDerWaalsContact CZ-CD1 3.45Å; Y242-I246 PolarHBondContact O-N 3.13Å; Y242-I246 WeakPolarHBondContact OH-CD1 3.31Å
243	V	94.6	Very high	94.3	Very high	0 Å²	0	47.6 Å²	47.6	0%	0	27%	0.268	C	S	.	.	H	α-helix	trans	-66	-40.8	176.2	174.3	0	0	0	0	111.4	F231 Y239 Q240 S247 L335 T338	F231-V243 HydrophobicContact CB-CG2 4.18Å; F231-V243 HydrophobicContact CD1-CG2 3.97Å; F231-V243 HydrophobicContact CD2-CG1 4.25Å; F231-V243 HydrophobicContact CD2-CG2 3.95Å; F231-V243 HydrophobicContact CE1-CG2 4.35Å; F231-V243 HydrophobicContact CE2-CG2 4.32Å; F231-V243 HydrophobicContact CG-CG2 3.77Å; Y239-V243 HydrophobicContact CD2-CG2 3.62Å; Y239-V243 HydrophobicContact CE2-CG2 3.42Å; Y239-V243 VanDerWaalsContact CE2-CG2 3.42Å; Y239-V243 PolarHBondContact O-N 2.97Å; Q240-V243 PolarHBondContact O-N 3.26Å; V243-S247 WeakPolarHBondContact O-CB 3.43Å; V243-S247 PolarHBondContact O-N 3.39Å; V243-S247 PolarHBondContact O-OG 3.46Å; V243-L335 HydrophobicContact CG1-CD1 4.19Å; V243-T338 HydrophobicContact CB-CG2 4.19Å; V243-T338 HydrophobicContact CG1-CG2 4.35Å; V243-T338 HydrophobicContact CG2-CG2 4.06Å
244	I	96.3	Very high	94.5	Very high	70 Å²	70	45 Å²	45	36%	0.359	26%	0.259	S	S	.	.	H	α-helix	trans	-60.3	-48.5	173.5	-70	167	0	0	0	109.7	Q240 A241 I246 S247 L248 L335 F339	Q240-I244 WeakPolarHBondContact O-CG1 3.48Å; Q240-I244 PolarHBondContact O-N 3.23Å; A241-I244 PolarHBondContact O-N 2.9Å; I244-I246 PolarHBondContact O-N 3.43Å; I244-S247 PolarHBondContact O-N 2.84Å; I244-S247 VanDerWaalsContact O-N 3.16Å; I244-L248 HydrophobicContact CG2-CD1 3.75Å; I244-L248 HydrophobicContact CG2-CG 4.1Å; I244-L248 WeakPolarHBondContact O-CB 3.36Å; I244-L248 VanDerWaalsContact O-CG 3.28Å; I244-L248 WeakPolarHBondContact O-CG 3.49Å; I244-L248 PolarHBondContact O-N 3.41Å; I244-L335 HydrophobicContact CG1-CD1 4.24Å; I244-F339 HydrophobicContact CD1-CE2 4.48Å; I244-F339 HydrophobicContact CD1-CZ 3.75Å; I244-F339 HydrophobicContact CG1-CE2 4.28Å; I244-F339 HydrophobicContact CG1-CZ 3.98Å
245	L	95.9	Very high	94.8	Very high	80 Å²	80	46.8 Å²	46.8	42%	0.419	27%	0.265	S	S	.	.	H	α-helix	trans	-56.1	-50.8	179.4	178	67.3	0	0	0	111.4	A241 Y242 S247 L248 I249	A241-L245 WeakPolarHBondContact O-CB 3.16Å; A241-L245 PolarHBondContact O-N 3.37Å; Y242-L245 WeakPolarHBondContact O-CB 3.14Å; Y242-L245 PolarHBondContact O-N 3.21Å; L245-S247 PolarHBondContact O-N 2.92Å; L245-L248 PolarHBondContact O-N 3.39Å; L245-I249 HydrophobicContact CD1-CD1 3.61Å; L245-I249 HydrophobicContact CD1-CG1 4.27Å; L245-I249 HydrophobicContact CG-CD1 3.91Å; L245-I249 WeakPolarHBondContact O-CB 3.42Å; L245-I249 WeakPolarHBondContact O-CG1 3.34Å; L245-I249 PolarHBondContact O-N 3.33Å
246	I	94.9	Very high	95	Very high	0 Å²	0	47 Å²	47	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-58.1	-49.2	175.6	-80.1	-175.8	0	0	0	110.5	W162 V209 L213 F231 Y242 I244 L248 I249 S250	W162-I246 HydrophobicContact CD2-CD1 4.22Å; W162-I246 HydrophobicContact CD2-CG2 3.81Å; W162-I246 HydrophobicContact CE3-CG2 3.39Å; W162-I246 HydrophobicContact CG-CD1 4.16Å; W162-I246 HydrophobicContact CH2-CG2 3.62Å; W162-I246 HydrophobicContact CZ2-CG2 4.03Å; W162-I246 HydrophobicContact CZ3-CG2 3.28Å; V209-I246 HydrophobicContact CG1-CG1 4.31Å; L213-I246 HydrophobicContact CD1-CD1 4.48Å; F231-I246 HydrophobicContact CE2-CD1 4.25Å; F231-I246 HydrophobicContact CE2-CG2 4.29Å; F231-I246 HydrophobicContact CZ-CD1 3.7Å; Y242-I246 HydrophobicContact CD1-CD1 4.01Å; Y242-I246 HydrophobicContact CE1-CD1 3.22Å; Y242-I246 HydrophobicContact CE1-CG1 4.08Å; Y242-I246 HydrophobicContact CE2-CD1 4.37Å; Y242-I246 VanDerWaalsContact CZ-CD1 3.45Å; Y242-I246 PolarHBondContact O-N 3.13Å; Y242-I246 WeakPolarHBondContact OH-CD1 3.31Å; I244-I246 PolarHBondContact O-N 3.43Å; I246-L248 VanDerWaalsContact C-N 3.28Å; I246-L248 PolarHBondContact O-N 3.16Å; I246-I249 PolarHBondContact O-N 2.87Å; I246-S250 VanDerWaalsContact O-CB 3.25Å; I246-S250 WeakPolarHBondContact O-CB 3.38Å; I246-S250 PolarHBondContact O-N 3.38Å; I246-S250 PolarHBondContact O-OG 3.45Å
247	S	95.9	Very high	95.2	Very high	3 Å²	3	45.1 Å²	45.1	2%	0.021	25%	0.253	C	S	.	.	H	α-helix	trans	-61.2	-37.6	-178	-57.2	0	0	0	0	112.2	V243 I244 L245 F251 F252	V243-S247 WeakPolarHBondContact O-CB 3.43Å; V243-S247 PolarHBondContact O-N 3.39Å; V243-S247 PolarHBondContact O-OG 3.46Å; I244-S247 PolarHBondContact O-N 2.84Å; I244-S247 VanDerWaalsContact O-N 3.16Å; L245-S247 PolarHBondContact O-N 2.92Å; S247-F251 WeakPolarHBondContact O-CB 3.27Å; S247-F251 PolarHBondContact O-N 3.3Å; S247-F251 VanDerWaalsContact O-N 3.1Å; S247-F252 WeakPolarHBondContact O-CD2 3.39Å; S247-F252 PolarHBondContact O-N 3.31Å; S247-F252 VanDerWaalsContact O-N 3.13Å
248	L	96.7	Very high	95.2	Very high	70 Å²	70	40.5 Å²	40.5	37%	0.366	22%	0.223	S	C	.	.	I	π-helix	trans	-66.5	-49	176.5	-72.6	175.3	0	0	0	111.4	I244 L245 I246 F252 I253 P254	I244-L248 HydrophobicContact CG2-CD1 3.75Å; I244-L248 HydrophobicContact CG2-CG 4.1Å; I244-L248 WeakPolarHBondContact O-CB 3.36Å; I244-L248 VanDerWaalsContact O-CG 3.28Å; I244-L248 WeakPolarHBondContact O-CG 3.49Å; I244-L248 PolarHBondContact O-N 3.41Å; L245-L248 PolarHBondContact O-N 3.39Å; I246-L248 VanDerWaalsContact C-N 3.28Å; I246-L248 PolarHBondContact O-N 3.16Å; L248-F252 HydrophobicContact CD2-CB 4.04Å; L248-F252 HydrophobicContact CD2-CD2 4.33Å; L248-F252 HydrophobicContact CD2-CG 4.5Å; L248-F252 PolarHBondContact O-N 3.02Å; L248-I253 HydrophobicContact CB-CD1 4.14Å; L248-I253 HydrophobicContact CB-CG1 4.45Å; L248-I253 WeakPolarHBondContact O-CB 3.39Å; L248-I253 PolarHBondContact O-N 2.69Å; L248-P254 WeakPolarHBondContact O-CD 3.49Å
249	I	95.4	Very high	95.2	Very high	52 Å²	52	41.6 Å²	41.6	27%	0.267	22%	0.219	S	C	.	.	I	π-helix	trans	-71.6	-40.1	-176.9	-68.8	175.1	0	0	0	111.6	I166 V209 L245 I246 P254	I166-I249 HydrophobicContact CG2-CG2 3.88Å; V209-I249 HydrophobicContact CG1-CD1 4.34Å; V209-I249 HydrophobicContact CG2-CD1 4.13Å; L245-I249 HydrophobicContact CD1-CD1 3.61Å; L245-I249 HydrophobicContact CD1-CG1 4.27Å; L245-I249 HydrophobicContact CG-CD1 3.91Å; L245-I249 WeakPolarHBondContact O-CB 3.42Å; L245-I249 WeakPolarHBondContact O-CG1 3.34Å; L245-I249 PolarHBondContact O-N 3.33Å; I246-I249 PolarHBondContact O-N 2.87Å; I249-P254 WeakPolarHBondContact O-CD 3.36Å; I249-P254 WeakPolarHBondContact O-CG 3.37Å
250	S	94.1	Very high	95.3	Very high	0 Å²	0	48.2 Å²	48.2	0%	0	24%	0.244	C	C	.	.	I	π-helix	trans	-85	-19.1	-175.3	75.1	0	0	0	0	113.4	I246 F323	I246-S250 VanDerWaalsContact O-CB 3.25Å; I246-S250 WeakPolarHBondContact O-CB 3.38Å; I246-S250 PolarHBondContact O-N 3.38Å; I246-S250 PolarHBondContact O-OG 3.45Å; S250-F323 WeakPolarHBondContact O-CZ 3.46Å
251	F	95.5	Very high	95.2	Very high	13 Å²	13	46.2 Å²	46.2	6%	0.057	24%	0.235	C	C	.	.	I	π-helix	trans	-140.3	-64.7	-174.9	-174.2	-104.2	0	0	0	114.5	S247 P254 F255 F323 W327 A328 T331	S247-F251 WeakPolarHBondContact O-CB 3.27Å; S247-F251 PolarHBondContact O-N 3.3Å; S247-F251 VanDerWaalsContact O-N 3.1Å; F251-P254 WeakPolarHBondContact O-CD 3.22Å; F251-F255 HydrophobicContact CZ-CD2 4.47Å; F251-F255 WeakPolarHBondContact O-CB 3.36Å; F251-F255 PolarHBondContact O-N 2.92Å; F251-F323 HydrophobicContact CD2-CE1 4.05Å; F251-F323 AromaticContact CD2-CZ 3.88Å; F251-F323 HydrophobicContact CD2-CZ 3.88Å; F251-F323 HydrophobicContact CE2-CE1 4.28Å; F251-W327 HydrophobicContact CD2-CB 4Å; F251-W327 HydrophobicContact CE2-CB 4.36Å; F251-A328 HydrophobicContact CE1-CB 4.11Å; F251-A328 HydrophobicContact CE2-CB 3.58Å; F251-A328 HydrophobicContact CZ-CB 3.26Å; F251-T331 HydrophobicContact CB-CG2 3.83Å; F251-T331 HydrophobicContact CD1-CG2 4.35Å; F251-T331 HydrophobicContact CG-CG2 4.26Å
252	F	96.5	Very high	94.9	Very high	69 Å²	69	43.7 Å²	43.7	30%	0.303	21%	0.214	S	C	.	.	I	π-helix	trans	-66.2	-47.3	-165.5	-68.6	-77.1	0	0	0	113.9	S247 L248 F255 L256 T331 L335	S247-F252 WeakPolarHBondContact O-CD2 3.39Å; S247-F252 PolarHBondContact O-N 3.31Å; S247-F252 VanDerWaalsContact O-N 3.13Å; L248-F252 HydrophobicContact CD2-CB 4.04Å; L248-F252 HydrophobicContact CD2-CD2 4.33Å; L248-F252 HydrophobicContact CD2-CG 4.5Å; L248-F252 PolarHBondContact O-N 3.02Å; F252-F255 PolarHBondContact O-N 3.43Å; F252-L256 WeakPolarHBondContact O-CG 3.35Å; F252-L256 PolarHBondContact O-N 3.37Å; F252-L256 VanDerWaalsContact O-N 3.08Å; F252-T331 HydrophobicContact CE2-CG2 4.37Å; F252-L335 HydrophobicContact CE2-CD2 4.23Å; F252-L335 HydrophobicContact CZ-CD2 4.37Å
253	I	96.4	Very high	94.6	Very high	86 Å²	86	48 Å²	48	44%	0.441	24%	0.236	S	C	.	.	H	α-helix	trans	-64.7	-51.6	177.6	-65.6	169.5	0	0	0	110.5	L248 F255 L256 V257	L248-I253 HydrophobicContact CB-CD1 4.14Å; L248-I253 HydrophobicContact CB-CG1 4.45Å; L248-I253 WeakPolarHBondContact O-CB 3.39Å; L248-I253 PolarHBondContact O-N 2.69Å; I253-F255 VanDerWaalsContact C-N 3.31Å; I253-F255 PolarHBondContact O-N 2.93Å; I253-L256 PolarHBondContact O-N 3.07Å; I253-V257 HydrophobicContact CG2-CG2 4.34Å; I253-V257 WeakPolarHBondContact O-CG2 3.43Å; I253-V257 PolarHBondContact O-N 3.37Å
254	P	95.3	Very high	94.3	Very high	4 Å²	4	48.8 Å²	48.8	3%	0.026	25%	0.245	C	C	.	.	H	α-helix	trans	-54	-45.6	174.4	-24.9	30.1	0	0	0	112.9	V169 L248 I249 F251 L256 V257 I258	V169-P254 HydrophobicContact CG1-CB 3.5Å; V169-P254 VanDerWaalsContact CG1-CB 3.5Å; V169-P254 HydrophobicContact CG1-CG 3.28Å; L248-P254 WeakPolarHBondContact O-CD 3.49Å; I249-P254 WeakPolarHBondContact O-CD 3.36Å; I249-P254 WeakPolarHBondContact O-CG 3.37Å; F251-P254 WeakPolarHBondContact O-CD 3.22Å; P254-L256 PolarHBondContact O-N 3.41Å; P254-V257 PolarHBondContact O-N 3.12Å; P254-I258 HydrophobicContact CB-CD1 4.19Å; P254-I258 WeakPolarHBondContact O-CB 3.42Å; P254-I258 WeakPolarHBondContact O-CD1 3.43Å; P254-I258 WeakPolarHBondContact O-CG1 3.33Å; P254-I258 PolarHBondContact O-N 2.92Å
255	F	95.4	Very high	93.8	Very high	55 Å²	55	45.6 Å²	45.6	24%	0.241	23%	0.228	C	C	.	.	H	α-helix	trans	-56.3	-50.1	179	171.6	-99.5	0	0	0	111.6	F251 F252 I253 L259 F320 I324	F251-F255 HydrophobicContact CZ-CD2 4.47Å; F251-F255 WeakPolarHBondContact O-CB 3.36Å; F251-F255 PolarHBondContact O-N 2.92Å; F252-F255 PolarHBondContact O-N 3.43Å; I253-F255 VanDerWaalsContact C-N 3.31Å; I253-F255 PolarHBondContact O-N 2.93Å; F255-L259 HydrophobicContact CE1-CD2 4.1Å; F255-L259 HydrophobicContact CZ-CD2 4.05Å; F255-L259 WeakPolarHBondContact O-CB 3.24Å; F255-L259 PolarHBondContact O-N 2.87Å; F255-F320 HydrophobicContact CD2-CE2 4.25Å; F255-F320 AromaticContact CD2-CZ 3.91Å; F255-F320 HydrophobicContact CD2-CZ 3.91Å; F255-F320 HydrophobicContact CE2-CZ 4.22Å; F255-I324 HydrophobicContact CD2-CD1 4Å; F255-I324 HydrophobicContact CD2-CG1 3.86Å; F255-I324 HydrophobicContact CE2-CD1 3.72Å; F255-I324 HydrophobicContact CE2-CG1 3.98Å
256	L	96.6	Very high	93.3	Very high	111 Å²	111	45.2 Å²	45.2	58%	0.581	23%	0.226	S	C	*	.	H	α-helix	trans	-64.5	-46.4	-178.9	-69.2	173.5	0	0	0	112.2	F252 I253 P254 L259 Y260	F252-L256 WeakPolarHBondContact O-CG 3.35Å; F252-L256 PolarHBondContact O-N 3.37Å; F252-L256 VanDerWaalsContact O-N 3.08Å; I253-L256 PolarHBondContact O-N 3.07Å; P254-L256 PolarHBondContact O-N 3.41Å; L256-L259 PolarHBondContact O-N 3.3Å; L256-Y260 WeakPolarHBondContact O-CB 3.43Å; L256-Y260 PolarHBondContact O-N 3.49Å
257	V	96.1	Very high	93	Very high	51 Å²	51	50.6 Å²	50.6	31%	0.309	26%	0.255	S	S	.	.	H	α-helix	trans	-67.3	-42.4	-178.6	177	0	0	0	0	111.2	L173 I177 I253 P254 Y260 S261	L173-V257 HydrophobicContact CD1-CB 3.75Å; L173-V257 HydrophobicContact CD1-CG1 3.55Å; I177-V257 HydrophobicContact CD1-CG1 4.2Å; I177-V257 HydrophobicContact CG1-CG1 4.17Å; I253-V257 HydrophobicContact CG2-CG2 4.34Å; I253-V257 WeakPolarHBondContact O-CG2 3.43Å; I253-V257 PolarHBondContact O-N 3.37Å; P254-V257 PolarHBondContact O-N 3.12Å; V257-Y260 PolarHBondContact O-N 3.39Å; V257-S261 WeakPolarHBondContact O-CB 3.46Å; V257-S261 PolarHBondContact O-N 3.32Å; V257-S261 PolarHBondContact O-OG 2.85Å
258	I	93.3	Very high	92.4	Very high	1 Å²	1	51.8 Å²	51.8	1%	0.005	26%	0.262	C	S	.	.	H	α-helix	trans	-67.5	-44	178.7	-65.8	169.6	0	0	0	110	L173 P254 Y260 S261 F262 F320	L173-I258 HydrophobicContact CD1-CD1 4.37Å; L173-I258 HydrophobicContact CD1-CG1 3.77Å; P254-I258 HydrophobicContact CB-CD1 4.19Å; P254-I258 WeakPolarHBondContact O-CB 3.42Å; P254-I258 WeakPolarHBondContact O-CD1 3.43Å; P254-I258 WeakPolarHBondContact O-CG1 3.33Å; P254-I258 PolarHBondContact O-N 2.92Å; I258-Y260 PolarHBondContact O-N 2.7Å; I258-S261 WeakPolarHBondContact O-CB 3.2Å; I258-S261 PolarHBondContact O-N 3.44Å; I258-F262 HydrophobicContact CG2-CD2 3.4Å; I258-F262 HydrophobicContact CG2-CE2 3.14Å; I258-F262 HydrophobicContact CG2-CZ 4.31Å; I258-F262 WeakPolarHBondContact O-CD2 3.34Å; I258-F262 PolarHBondContact O-N 3.43Å; I258-F320 HydrophobicContact CB-CD2 4.03Å; I258-F320 HydrophobicContact CB-CE2 3.65Å; I258-F320 HydrophobicContact CB-CZ 4.04Å; I258-F320 HydrophobicContact CD1-CD2 4.28Å; I258-F320 HydrophobicContact CD1-CE2 4.29Å; I258-F320 HydrophobicContact CG2-CB 4.28Å; I258-F320 HydrophobicContact CG2-CD1 4Å; I258-F320 HydrophobicContact CG2-CD2 3.24Å; I258-F320 HydrophobicContact CG2-CE1 4.05Å; I258-F320 HydrophobicContact CG2-CE2 3.32Å; I258-F320 HydrophobicContact CG2-CG 3.59Å; I258-F320 HydrophobicContact CG2-CZ 3.72Å
259	L	94.1	Very high	91.6	Very high	66 Å²	66	50 Å²	50	35%	0.346	25%	0.253	S	S	.	.	H	α-helix	trans	-58	-49.4	174.9	179.4	63.6	0	0	0	111.3	F255 L256 S261 F262 M263 F320	F255-L259 HydrophobicContact CE1-CD2 4.1Å; F255-L259 HydrophobicContact CZ-CD2 4.05Å; F255-L259 WeakPolarHBondContact O-CB 3.24Å; F255-L259 PolarHBondContact O-N 2.87Å; L256-L259 PolarHBondContact O-N 3.3Å; L259-S261 VanDerWaalsContact C-N 3.32Å; L259-S261 PolarHBondContact O-N 3.27Å; L259-F262 PolarHBondContact O-N 2.87Å; L259-M263 HydrophobicContact CD1-CG 4.24Å; L259-M263 HydrophobicContact CG-CG 4.45Å; L259-M263 VanDerWaalsContact O-CG 3.31Å; L259-M263 WeakPolarHBondContact O-CG 3.36Å; L259-M263 PolarHBondContact O-N 3.45Å; L259-F320 HydrophobicContact CB-CZ 4.25Å
260	Y	94.3	Very high	90.9	Very high	153 Å²	153	56 Å²	56	60%	0.6	27%	0.272	S	S	*	.	H	α-helix	trans	-56.3	-47.2	176	172.7	-96.6	0	0	0	111.7	F180 L256 V257 I258 F262 M263 G264	F180-Y260 HydrophobicContact CE1-CE1 4.36Å; F180-Y260 HydrophobicContact CE2-CE1 4.1Å; F180-Y260 AromaticContact CZ-CE1 3.77Å; F180-Y260 HydrophobicContact CZ-CE1 3.77Å; L256-Y260 WeakPolarHBondContact O-CB 3.43Å; L256-Y260 PolarHBondContact O-N 3.49Å; V257-Y260 PolarHBondContact O-N 3.39Å; I258-Y260 PolarHBondContact O-N 2.7Å; Y260-F262 VanDerWaalsContact C-N 3.34Å; Y260-F262 PolarHBondContact O-N 2.9Å; Y260-M263 PolarHBondContact O-N 3.27Å; Y260-G264 PolarHBondContact O-N 2.95Å
261	S	91.6	Very high	90.2	Very high	4 Å²	4	60.2 Å²	60.2	3%	0.028	29%	0.292	C	S	.	.	H	α-helix	trans	-57.6	-46.3	177.6	-61.9	0	0	0	0	111.3	V257 I258 L259 G264 I265	V257-S261 WeakPolarHBondContact O-CB 3.46Å; V257-S261 PolarHBondContact O-N 3.32Å; V257-S261 PolarHBondContact O-OG 2.85Å; I258-S261 WeakPolarHBondContact O-CB 3.2Å; I258-S261 PolarHBondContact O-N 3.44Å; L259-S261 VanDerWaalsContact C-N 3.32Å; L259-S261 PolarHBondContact O-N 3.27Å; S261-G264 PolarHBondContact O-N 3.25Å; S261-I265 WeakPolarHBondContact O-CD1 3.35Å; S261-I265 WeakPolarHBondContact O-CG1 3.5Å; S261-I265 PolarHBondContact O-N 3.05Å
262	F	88.1	Confident	89.3	Confident	6 Å²	6	61.8 Å²	61.8	3%	0.026	30%	0.3	C	S	.	.	H	α-helix	trans	-66	-42.7	177.9	-80.7	-62.7	0	0	0	113.3	I258 L259 Y260 G264 I265 L266 F313 I316 L317 F320	I258-F262 HydrophobicContact CG2-CD2 3.4Å; I258-F262 HydrophobicContact CG2-CE2 3.14Å; I258-F262 HydrophobicContact CG2-CZ 4.31Å; I258-F262 WeakPolarHBondContact O-CD2 3.34Å; I258-F262 PolarHBondContact O-N 3.43Å; L259-F262 PolarHBondContact O-N 2.87Å; Y260-F262 VanDerWaalsContact C-N 3.34Å; Y260-F262 PolarHBondContact O-N 2.9Å; F262-G264 VanDerWaalsContact C-N 3.31Å; F262-G264 PolarHBondContact O-N 3.39Å; F262-I265 PolarHBondContact O-N 2.93Å; F262-L266 WeakPolarHBondContact O-CB 3.09Å; F262-L266 WeakPolarHBondContact O-CG 3.29Å; F262-L266 PolarHBondContact O-N 2.75Å; F262-F313 AromaticContact CD1-CE2 3.57Å; F262-F313 HydrophobicContact CD1-CE2 3.57Å; F262-F313 AromaticContact CD1-CZ 3.98Å; F262-F313 HydrophobicContact CD1-CZ 3.98Å; F262-F313 HydrophobicContact CE1-CD2 4.47Å; F262-F313 AromaticContact CE1-CE2 3.91Å; F262-F313 HydrophobicContact CE1-CE2 3.91Å; F262-F313 HydrophobicContact CE1-CZ 4.47Å; F262-I316 HydrophobicContact CE1-CB 4.31Å; F262-I316 HydrophobicContact CE1-CG2 3.79Å; F262-I316 HydrophobicContact CZ-CB 4.26Å; F262-I316 HydrophobicContact CZ-CG2 3.43Å; F262-I316 VanDerWaalsContact CZ-CG2 3.43Å; F262-I316 WeakPolarHBondContact CZ-O 3.22Å; F262-L317 HydrophobicContact CD1-CD1 4.11Å; F262-L317 HydrophobicContact CE1-CB 4.15Å; F262-L317 HydrophobicContact CE1-CD1 4.3Å; F262-L317 HydrophobicContact CG-CD1 4.37Å; F262-F320 HydrophobicContact CD2-CB 4.3Å; F262-F320 AromaticContact CD2-CD1 3.45Å; F262-F320 HydrophobicContact CD2-CD1 3.45Å; F262-F320 VanDerWaalsContact CD2-CD1 3.45Å; F262-F320 AromaticContact CD2-CE1 3.84Å; F262-F320 HydrophobicContact CD2-CE1 3.84Å; F262-F320 AromaticContact CD2-CG 3.94Å; F262-F320 HydrophobicContact CD2-CG 3.94Å; F262-F320 HydrophobicContact CE2-CB 3.36Å; F262-F320 AromaticContact CE2-CD1 3.41Å; F262-F320 HydrophobicContact CE2-CD1 3.41Å; F262-F320 VanDerWaalsContact CE2-CD1 3.41Å; F262-F320 HydrophobicContact CE2-CD2 4.25Å; F262-F320 HydrophobicContact CE2-CE1 4.19Å; F262-F320 AromaticContact CE2-CG 3.42Å; F262-F320 HydrophobicContact CE2-CG 3.42Å; F262-F320 VanDerWaalsContact CE2-CG 3.42Å; F262-F320 HydrophobicContact CZ-CB 3.81Å; F262-F320 HydrophobicContact CZ-CD1 4.43Å; F262-F320 HydrophobicContact CZ-CG 4.34Å
263	M	89.6	Confident	88.2	Confident	113 Å²	113	60.7 Å²	60.7	56%	0.557	30%	0.304	S	S	*	.	H	α-helix	trans	-61.2	-42.6	177.5	-69.2	-55.7	-68	0	0	111	L259 Y260 L266 N267	L259-M263 HydrophobicContact CD1-CG 4.24Å; L259-M263 HydrophobicContact CG-CG 4.45Å; L259-M263 VanDerWaalsContact O-CG 3.31Å; L259-M263 WeakPolarHBondContact O-CG 3.36Å; L259-M263 PolarHBondContact O-N 3.45Å; Y260-M263 PolarHBondContact O-N 3.27Å; M263-L266 PolarHBondContact O-N 2.92Å; M263-N267 WeakPolarHBondContact O-CB 3.4Å; M263-N267 PolarHBondContact O-N 3.29Å
264	G	88.9	Confident	87	Confident	18 Å²	18	61.4 Å²	61.4	19%	0.186	31%	0.308	C	S	.	.	H	α-helix	trans	-62.4	-41.7	174.4	0	0	0	0	0	113.2	Y260 S261 F262 T268	Y260-G264 PolarHBondContact O-N 2.95Å; S261-G264 PolarHBondContact O-N 3.25Å; F262-G264 VanDerWaalsContact C-N 3.31Å; F262-G264 PolarHBondContact O-N 3.39Å; G264-T268 WeakPolarHBondContact O-CB 3.48Å; G264-T268 PolarHBondContact O-N 3.23Å; G264-T268 PolarHBondContact O-OG1 3.21Å
265	I	86.2	Confident	85.8	Confident	2 Å²	2	68.5 Å²	68.5	1%	0.01	34%	0.335	C	S	.	.	H	α-helix	trans	-64.5	-49.1	176.2	-65.1	161.3	0	0	0	110.8	R179 F180 I183 V184 S261 F262 N267 T268 L269 F313	R179-I265 HydrophobicContact CB-CD1 4.19Å; F180-I265 HydrophobicContact CB-CD1 4.43Å; I183-I265 HydrophobicContact CB-CG1 4.42Å; I183-I265 HydrophobicContact CD1-CD1 4.47Å; I183-I265 HydrophobicContact CD1-CG1 4.38Å; I183-I265 HydrophobicContact CD1-CG2 3.85Å; I183-I265 HydrophobicContact CG2-CG2 4.06Å; V184-I265 HydrophobicContact CG2-CB 4.48Å; V184-I265 HydrophobicContact CG2-CG1 3.93Å; S261-I265 WeakPolarHBondContact O-CD1 3.35Å; S261-I265 WeakPolarHBondContact O-CG1 3.5Å; S261-I265 PolarHBondContact O-N 3.05Å; F262-I265 PolarHBondContact O-N 2.93Å; I265-N267 VanDerWaalsContact C-N 3.32Å; I265-N267 PolarHBondContact O-N 3.49Å; I265-T268 PolarHBondContact O-N 2.9Å; I265-L269 HydrophobicContact CG2-CD1 3.88Å; I265-L269 HydrophobicContact CG2-CG 4.25Å; I265-L269 WeakPolarHBondContact O-CG 3.45Å; I265-L269 PolarHBondContact O-N 3.39Å; I265-F313 HydrophobicContact CB-CD2 4.29Å; I265-F313 HydrophobicContact CB-CE2 3.75Å; I265-F313 HydrophobicContact CD1-CD2 4.36Å; I265-F313 HydrophobicContact CD1-CE2 4.14Å; I265-F313 HydrophobicContact CG2-CD2 3.35Å; I265-F313 HydrophobicContact CG2-CE2 3.2Å; I265-F313 HydrophobicContact CG2-CG 4.23Å; I265-F313 HydrophobicContact CG2-CZ 4.03Å
266	L	85.3	Confident	84.3	Confident	73 Å²	73	70.3 Å²	70.3	38%	0.382	35%	0.346	S	S	.	.	H	α-helix	trans	-59.8	-42.9	179.1	-73.6	175	0	0	0	111.8	F262 M263 L269 R270 F313	F262-L266 WeakPolarHBondContact O-CB 3.09Å; F262-L266 WeakPolarHBondContact O-CG 3.29Å; F262-L266 PolarHBondContact O-N 2.75Å; M263-L266 PolarHBondContact O-N 2.92Å; L266-L269 PolarHBondContact O-N 3.23Å; L266-R270 WeakPolarHBondContact O-CB 3.38Å; L266-R270 PolarHBondContact O-N 3.2Å; L266-F313 HydrophobicContact CD2-CE1 3.54Å; L266-F313 HydrophobicContact CD2-CZ 3.45Å; L266-F313 VanDerWaalsContact CD2-CZ 3.45Å; L266-F313 HydrophobicContact CG-CE1 4.4Å; L266-F313 HydrophobicContact CG-CZ 3.8Å
267	N	87.1	Confident	82.5	Confident	112 Å²	112	72.8 Å²	72.8	60%	0.599	35%	0.354	S	S	*	.	H	α-helix	trans	-62.9	-43.8	177.6	-170.2	29	0	0	0	111.5	M263 I265 L269 R270 H271	M263-N267 WeakPolarHBondContact O-CB 3.4Å; M263-N267 PolarHBondContact O-N 3.29Å; I265-N267 VanDerWaalsContact C-N 3.32Å; I265-N267 PolarHBondContact O-N 3.49Å; N267-L269 PolarHBondContact O-N 3.27Å; N267-R270 PolarHBondContact O-N 3.36Å; N267-H271 WeakPolarHBondContact O-CB 2.93Å; N267-H271 PolarHBondContact O-N 3.31Å
268	T	84.3	Confident	80.6	Confident	28 Å²	28	74.4 Å²	74.4	17%	0.172	37%	0.368	C	S	.	.	H	α-helix	trans	-62.7	-43.3	176.9	-57	0	0	0	0	111.5	I183 G264 I265 H271 N272	I183-T268 HydrophobicContact CG2-CG2 4.43Å; G264-T268 WeakPolarHBondContact O-CB 3.48Å; G264-T268 PolarHBondContact O-N 3.23Å; G264-T268 PolarHBondContact O-OG1 3.21Å; I265-T268 PolarHBondContact O-N 2.9Å; T268-H271 PolarHBondContact O-N 3Å; T268-N272 WeakPolarHBondContact O-CB 3.49Å; T268-N272 PolarHBondContact O-N 2.9Å; T268-N272 PolarHBondContact O-ND2 2.94Å
269	L	79.8	Confident	78.6	Confident	34 Å²	34	83.6 Å²	83.6	18%	0.178	40%	0.404	C	S	.	.	H	α-helix	trans	-64.3	-43.7	176.8	-70.1	175.7	0	0	0	111.8	I265 L266 N267 N272 A273 F313	I265-L269 HydrophobicContact CG2-CD1 3.88Å; I265-L269 HydrophobicContact CG2-CG 4.25Å; I265-L269 WeakPolarHBondContact O-CG 3.45Å; I265-L269 PolarHBondContact O-N 3.39Å; L266-L269 PolarHBondContact O-N 3.23Å; N267-L269 PolarHBondContact O-N 3.27Å; L269-N272 PolarHBondContact O-N 2.99Å; L269-A273 WeakPolarHBondContact O-CB 3.29Å; L269-A273 PolarHBondContact O-N 3.09Å; L269-F313 HydrophobicContact CD1-CD1 3.98Å; L269-F313 HydrophobicContact CD1-CE1 4.2Å; L269-F313 HydrophobicContact CD1-CG 4.18Å
270	R	81.8	Confident	76.2	Confident	178 Å²	178	84 Å²	84	67%	0.672	41%	0.41	S	S	*	.	H	α-helix	trans	-61.7	-45.6	176	-175.3	178	178.6	173	-0.1	111.1	L266 N267 N272 A273 L274	L266-R270 WeakPolarHBondContact O-CB 3.38Å; L266-R270 PolarHBondContact O-N 3.2Å; N267-R270 PolarHBondContact O-N 3.36Å; R270-N272 VanDerWaalsContact C-N 3.34Å; R270-N272 PolarHBondContact O-N 3.3Å; R270-A273 PolarHBondContact O-N 3.25Å; R270-L274 HydrophobicContact CG-CD1 4.22Å; R270-L274 WeakPolarHBondContact O-CG 2.98Å; R270-L274 PolarHBondContact O-N 3.17Å
271	H	79.4	Confident	73.9	Confident	88 Å²	88	86 Å²	86	41%	0.407	43%	0.425	S	S	.	.	H	α-helix	trans	-62.6	-41.9	178.2	-168.5	-15.7	0	0	0	111.5	N267 T268 L274 R275	N267-H271 WeakPolarHBondContact O-CB 2.93Å; N267-H271 PolarHBondContact O-N 3.31Å; T268-H271 PolarHBondContact O-N 3Å; H271-L274 PolarHBondContact O-N 2.88Å; H271-R275 PolarHBondContact CE1-NE 3.22Å; H271-R275 PolarHBondContact ND1-NE 3.16Å; H271-R275 PolarHBondContact NE2-NH2 2.8Å; H271-R275 PolarHBondContact O-N 2.82Å
272	N	74.9	Confident	71.9	Confident	45 Å²	45	88.5 Å²	88.5	24%	0.241	45%	0.452	C	S	.	.	H	α-helix	trans	-66.3	-39.2	177.5	-69.1	-18.5	0	0	0	112	T268 L269 R270 R275 I276	T268-N272 WeakPolarHBondContact O-CB 3.49Å; T268-N272 PolarHBondContact O-N 2.9Å; T268-N272 PolarHBondContact O-ND2 2.94Å; L269-N272 PolarHBondContact O-N 2.99Å; R270-N272 VanDerWaalsContact C-N 3.34Å; R270-N272 PolarHBondContact O-N 3.3Å; N272-R275 PolarHBondContact O-N 3.17Å; N272-I276 WeakPolarHBondContact O-CD1 3.24Å; N272-I276 VanDerWaalsContact O-CG1 3.28Å; N272-I276 WeakPolarHBondContact O-CG1 3.34Å; N272-I276 PolarHBondContact O-N 3.45Å; N272-I276 VanDerWaalsContact O-N 3.15Å
273	A	73.6	Confident	70	Confident	46 Å²	46	93.7 Å²	93.7	38%	0.38	48%	0.479	S	S	.	.	H	α-helix	trans	-63.3	-43.9	174.4	0	0	0	0	0	111.8	L269 R270 R275 I276 H277	L269-A273 WeakPolarHBondContact O-CB 3.29Å; L269-A273 PolarHBondContact O-N 3.09Å; R270-A273 PolarHBondContact O-N 3.25Å; A273-R275 PolarHBondContact O-N 3.36Å; A273-I276 PolarHBondContact O-N 3.13Å; A273-H277 PolarHBondContact O-CD2 3.45Å; A273-H277 VanDerWaalsContact O-CD2 3.25Å; A273-H277 PolarHBondContact O-N 2.92Å; A273-H277 VanDerWaalsContact O-N 3.09Å
274	L	71.5	Confident	67.9	Low	101 Å²	101	93 Å²	93	53%	0.529	48%	0.484	S	S	.	.	H	α-helix	trans	-62.8	-39.9	176	-69.7	173.3	0	0	0	112	R270 H271 I276 H277 S278	R270-L274 HydrophobicContact CG-CD1 4.22Å; R270-L274 WeakPolarHBondContact O-CG 2.98Å; R270-L274 PolarHBondContact O-N 3.17Å; H271-L274 PolarHBondContact O-N 2.88Å; L274-I276 VanDerWaalsContact C-N 3.31Å; L274-I276 PolarHBondContact O-N 3.41Å; L274-H277 PolarHBondContact O-N 3.18Å; L274-S278 WeakPolarHBondContact O-CB 3.11Å; L274-S278 PolarHBondContact O-N 3.49Å; L274-S278 PolarHBondContact O-OG 3.03Å; L274-S278 VanDerWaalsContact O-OG 3.06Å
275	R	70.5	Confident	66	Low	154 Å²	154	99.3 Å²	99.3	58%	0.581	51%	0.512	S	S	*	.	H	α-helix	trans	-63.3	-34.3	175.8	-76.8	-171.6	-166.5	-134.9	-1.7	113.5	H271 N272 A273 S278	H271-R275 PolarHBondContact CE1-NE 3.22Å; H271-R275 PolarHBondContact ND1-NE 3.16Å; H271-R275 PolarHBondContact NE2-NH2 2.8Å; H271-R275 PolarHBondContact O-N 2.82Å; N272-R275 PolarHBondContact O-N 3.17Å; A273-R275 PolarHBondContact O-N 3.36Å; R275-S278 VanDerWaalsContact CA-OG 3.3Å; R275-S278 WeakPolarHBondContact CA-OG 3.42Å; R275-S278 PolarHBondContact O-OG 3.16Å; R275-S278 VanDerWaalsContact O-OG 3.08Å
276	I	62.9	Low	64.1	Low	93 Å²	93	103.1 Å²	103.1	48%	0.477	54%	0.539	S	S	.	.	H	α-helix	trans	-72.7	-41.9	178.8	-66.9	164.6	0	0	0	110.1	N272 A273 L274 S278 Y279	N272-I276 WeakPolarHBondContact O-CD1 3.24Å; N272-I276 VanDerWaalsContact O-CG1 3.28Å; N272-I276 WeakPolarHBondContact O-CG1 3.34Å; N272-I276 PolarHBondContact O-N 3.45Å; N272-I276 VanDerWaalsContact O-N 3.15Å; A273-I276 PolarHBondContact O-N 3.13Å; L274-I276 VanDerWaalsContact C-N 3.31Å; L274-I276 PolarHBondContact O-N 3.41Å; I276-S278 VanDerWaalsContact C-N 3.32Å; I276-Y279 PolarHBondContact O-N 3.08Å
277	H	59.6	Low	62.3	Low	162 Å²	162	106.4 Å²	106.4	75%	0.75	55%	0.553	S	S	*	*	H	α-helix	trans	-72	-24.8	175.9	-76.7	-66.8	0	0	0	113.6	A273 L274 Y279	A273-H277 PolarHBondContact O-CD2 3.45Å; A273-H277 VanDerWaalsContact O-CD2 3.25Å; A273-H277 PolarHBondContact O-N 2.92Å; A273-H277 VanDerWaalsContact O-N 3.09Å; L274-H277 PolarHBondContact O-N 3.18Å; H277-Y279 VanDerWaalsContact C-N 3.3Å
278	S	56.8	Low	60.4	Low	85 Å²	85	104 Å²	104	59%	0.594	55%	0.548	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.8	1.8	177	65.3	0	0	0	0	114.1	L274 R275 I276 P280	L274-S278 WeakPolarHBondContact O-CB 3.11Å; L274-S278 PolarHBondContact O-N 3.49Å; L274-S278 PolarHBondContact O-OG 3.03Å; L274-S278 VanDerWaalsContact O-OG 3.06Å; R275-S278 VanDerWaalsContact CA-OG 3.3Å; R275-S278 WeakPolarHBondContact CA-OG 3.42Å; R275-S278 PolarHBondContact O-OG 3.16Å; R275-S278 VanDerWaalsContact O-OG 3.08Å; I276-S278 VanDerWaalsContact C-N 3.32Å; S278-P280 WeakPolarHBondContact O-CD 3.36Å
279	Y	49.8	Very low	58.8	Low	194 Å²	194	107.2 Å²	107.2	76%	0.761	57%	0.572	S	S	*	*	S	Bend	trans	-83.2	104.3	163.4	-118	-88.4	0	0	0	107.4	I276 H277 E281	I276-Y279 PolarHBondContact O-N 3.08Å; H277-Y279 VanDerWaalsContact C-N 3.3Å; Y279-E281 PolarHBondContact O-N 3.37Å; Y279-E281 VanDerWaalsContact O-N 3.09Å
280	P	45.4	Very low	57.4	Low	74 Å²	74	114.4 Å²	114.4	48%	0.481	60%	0.602	S	S	.	*			trans	-63.5	119.2	175.7	24.6	-28.9	0	0	0	107.8	S278 G282 I283	S278-P280 WeakPolarHBondContact O-CD 3.36Å; P280-G282 PolarHBondContact O-N 3.27Å; P280-I283 HydrophobicContact CB-CD1 4.49Å; P280-I283 HydrophobicContact CB-CG1 4.43Å; P280-I283 HydrophobicContact CG-CD1 3.73Å; P280-I283 HydrophobicContact CG-CG1 4.02Å
281	E	45.2	Very low	56.2	Low	196 Å²	196	112.2 Å²	112.2	92%	0.916	60%	0.602	S	S	*	*	T	Hydrogen-bonded Turn	trans	-55.5	-4.8	167.1	-76.1	-169.1	144.1	0	0	112.8	Y279	Y279-E281 PolarHBondContact O-N 3.37Å; Y279-E281 VanDerWaalsContact O-N 3.09Å
282	G	48.5	Very low	54.9	Low	57 Å²	57	111.6 Å²	111.6	59%	0.588	62%	0.62	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.1	-12.2	-173.6	0	0	0	0	0	118.3	P280	P280-G282 PolarHBondContact O-N 3.27Å
283	I	48.6	Very low	53.7	Low	115 Å²	115	116 Å²	116	59%	0.59	64%	0.643	S	S	*	*	S	Bend	trans	-103	-25.3	-169.2	-58.4	-179.8	0	0	0	114.1	P280	P280-I283 HydrophobicContact CB-CD1 4.49Å; P280-I283 HydrophobicContact CB-CG1 4.43Å; P280-I283 HydrophobicContact CG-CD1 3.73Å; P280-I283 HydrophobicContact CG-CG1 4.02Å
284	C	45.3	Very low	52.5	Low	99 Å²	99	123.1 Å²	123.1	67%	0.669	67%	0.67	S	S	*	*	S	Bend	trans	-95.5	-20.3	-176.8	-142.2	0	0	0	0	114.1	A288	C284-A288 WeakPolarHBondContact O-CB 3.36Å; C284-A288 PolarHBondContact O-N 3.5Å; C284-A288 VanDerWaalsContact O-N 3.16Å
285	L	50.1	Low	51.3	Low	149 Å²	149	122.7 Å²	122.7	78%	0.78	68%	0.676	S	S	*	*	H	α-helix	trans	-76.2	-28.3	-176.6	-145.1	90.9	0	0	0	113.3
286	S	46.4	Very low	50.4	Low	82 Å²	82	123.3 Å²	123.3	57%	0.573	69%	0.69	S	S	*	*	H	α-helix	trans	-85.6	-24.3	-179.2	66.1	0	0	0	0	113.8	S289	S286-S289 PolarHBondContact O-OG 2.89Å
287	Q	46	Very low	49.5	Very low	143 Å²	143	127.6 Å²	127.6	67%	0.668	71%	0.708	S	S	*	*	H	α-helix	trans	-92.9	-32.2	177	-101.5	177.2	-8.1	0	0	113.1	S289 K290	Q287-S289 VanDerWaalsContact C-N 3.32Å; Q287-S289 PolarHBondContact O-N 3.25Å; Q287-K290 PolarHBondContact O-N 2.91Å
288	A	48.3	Very low	49	Very low	60 Å²	60	130.2 Å²	130.2	50%	0.496	71%	0.711	S	S	.	*	H	α-helix	trans	-72	-24.2	178.2	0	0	0	0	0	113.3	C284 K290	C284-A288 WeakPolarHBondContact O-CB 3.36Å; C284-A288 PolarHBondContact O-N 3.5Å; C284-A288 VanDerWaalsContact O-N 3.16Å; A288-K290 PolarHBondContact O-N 3.44Å
289	S	50.4	Low	48.4	Very low	96 Å²	96	130.9 Å²	130.9	67%	0.671	71%	0.714	S	S	*	*	T	Hydrogen-bonded Turn	trans	-69.5	-19.4	173.3	66	0	0	0	0	113.2	S286 Q287	S286-S289 PolarHBondContact O-OG 2.89Å; Q287-S289 VanDerWaalsContact C-N 3.32Å; Q287-S289 PolarHBondContact O-N 3.25Å
290	K	50.1	Low	47.9	Very low	186 Å²	186	129 Å²	129	81%	0.809	71%	0.71	S	S	*	*	T	Hydrogen-bonded Turn	trans	-92	-10.9	-179.4	-106.7	-173.4	177.3	-175	0	114.9	Q287 A288	Q287-K290 PolarHBondContact O-N 2.91Å; A288-K290 PolarHBondContact O-N 3.44Å
291	L	56.9	Low	47.6	Very low	132 Å²	132	133.3 Å²	133.3	69%	0.691	72%	0.723	S	S	*	*	S	Bend	trans	-124.3	8.1	-171.6	-109.8	115.3	0	0	0	116	L293	L291-L293 PolarHBondContact O-N 2.83Å
292	G	52.8	Low	47.5	Very low	75 Å²	75	130.4 Å²	130.4	77%	0.773	71%	0.711	S	S	*	*			trans	57.9	14.4	166.1	0	0	0	0	0	116.5	M294	G292-M294 PolarHBondContact O-N 2.75Å
293	L	49.5	Very low	47.1	Very low	137 Å²	137	130.4 Å²	130.4	72%	0.717	70%	0.702	S	S	*	*			trans	-97.7	81.9	-173.5	-112.5	141.2	0	0	0	110.1	L291 S295	L291-L293 PolarHBondContact O-N 2.83Å; L293-S295 VanDerWaalsContact C-N 3.29Å; L293-S295 PolarHBondContact O-N 2.74Å
294	M	48.8	Very low	46.9	Very low	195 Å²	195	130.2 Å²	130.2	96%	0.961	70%	0.702	S	S	*	*			trans	-69.2	80.8	167.9	-73.9	-179.2	77.1	0	0	110.2	G292	G292-M294 PolarHBondContact O-N 2.75Å
295	S	45.7	Very low	47	Very low	93 Å²	93	129 Å²	129	65%	0.65	69%	0.688	S	S	*	*			trans	-159.3	32.7	175.7	-175	0	0	0	0	116	L293	L293-S295 VanDerWaalsContact C-N 3.29Å; L293-S295 PolarHBondContact O-N 2.74Å
296	L	50.3	Low	46.8	Very low	167 Å²	167	124.3 Å²	124.3	87%	0.874	66%	0.663	S	S	*	*			trans	-149.4	40.4	174.1	-115.6	145.1	0	0	0	114.8	R298	L296-R298 PolarHBondContact O-N 2.77Å; L296-R298 VanDerWaalsContact O-N 3.16Å
297	Q	45.6	Very low	46.7	Very low	182 Å²	182	122.1 Å²	122.1	85%	0.85	65%	0.653	S	S	*	*			trans	-86.7	81.9	172.2	-164.3	148.5	-31.5	0	0	111.2
298	R	48.1	Very low	46.7	Very low	217 Å²	217	122.7 Å²	122.7	82%	0.819	65%	0.654	S	S	*	*			trans	-125.1	30	164.3	-95.3	-170	-173.8	172.2	4.4	116.9	L296	L296-R298 PolarHBondContact O-N 2.77Å; L296-R298 VanDerWaalsContact O-N 3.16Å
299	P	43.6	Very low	46.8	Very low	100 Å²	100	124.7 Å²	124.7	65%	0.649	65%	0.651	S	S	*	*	S	Bend	trans	-91.4	-21.2	171.8	28.1	-20.8	0	0	0	115
300	F	40.5	Very low	47	Very low	155 Å²	155	122.9 Å²	122.9	68%	0.68	64%	0.636	S	S	*	*	H	α-helix	trans	-84.4	-14.9	-170.9	-153.7	-102.1	0	0	0	115.3	S303 I304	F300-S303 PolarHBondContact O-OG 3.14Å; F300-I304 HydrophobicContact CD1-CD1 4.43Å; F300-I304 HydrophobicContact CE1-CD1 4.18Å
301	Q	39.6	Very low	47.4	Very low	163 Å²	163	122.3 Å²	122.3	76%	0.762	63%	0.629	S	S	*	*	H	α-helix	trans	-87.9	-16.7	-176.6	-162.9	162	-5.6	0	0	113.6
302	M	42.5	Very low	47.7	Very low	135 Å²	135	118 Å²	118	67%	0.665	61%	0.613	S	S	*	*	H	α-helix	trans	-82.7	-32.4	176.8	-89.8	-177	177.5	0	0	113.7	I304 D305 M306	M302-I304 PolarHBondContact O-N 3.05Å; M302-D305 PolarHBondContact O-N 3.16Å; M302-M306 WeakPolarHBondContact O-CG 3.42Å; M302-M306 PolarHBondContact O-N 3.36Å
303	S	40.5	Very low	48.5	Very low	57 Å²	57	115 Å²	115	40%	0.399	58%	0.578	S	S	.	*	H	α-helix	trans	-66.1	-37	-178.6	61.5	0	0	0	0	112.5	F300 G307	F300-S303 PolarHBondContact O-OG 3.14Å; S303-G307 PolarHBondContact O-N 3.18Å
304	I	43.8	Very low	49.7	Very low	112 Å²	112	110.9 Å²	110.9	57%	0.574	56%	0.559	S	S	*	*	H	α-helix	trans	-73	-35.7	177	-59.2	176.2	0	0	0	111.4	F300 M302 G307 F308	F300-I304 HydrophobicContact CD1-CD1 4.43Å; F300-I304 HydrophobicContact CE1-CD1 4.18Å; M302-I304 PolarHBondContact O-N 3.05Å; I304-G307 PolarHBondContact O-N 1.99Å; I304-F308 PolarHBondContact O-N 3.01Å
305	D	47.1	Very low	51.2	Low	73 Å²	73	102 Å²	102	39%	0.39	52%	0.515	S	S	.	.	H	α-helix	trans	-66.8	-37.7	175.4	-172.3	51.1	0	0	0	111.9	M302 F308 K309	M302-D305 PolarHBondContact O-N 3.16Å; D305-F308 PolarHBondContact O-N 2.67Å; D305-K309 WeakPolarHBondContact O-CB 3.42Å; D305-K309 PolarHBondContact O-N 3.28Å; D305-K309 IonicContact OD1-NZ 3.88Å; D305-K309 IonicContact OD2-NZ 2.76Å; D305-K309 PolarHBondContact OD2-NZ 3.22Å
306	M	46.6	Very low	52.7	Low	50 Å²	50	98.3 Å²	98.3	25%	0.246	49%	0.488	C	S	.	.	H	α-helix	trans	-65.6	-44	174.7	-70.5	-60.3	126.3	0	0	112.1	M302 F308 K309 T310	M302-M306 WeakPolarHBondContact O-CG 3.42Å; M302-M306 PolarHBondContact O-N 3.36Å; M306-F308 VanDerWaalsContact C-N 3.31Å; M306-F308 PolarHBondContact O-N 3.33Å; M306-K309 HydrophobicContact CE-CD 4.34Å; M306-K309 PolarHBondContact O-N 3.43Å; M306-T310 WeakPolarHBondContact O-CB 3.28Å; M306-T310 PolarHBondContact O-N 3.09Å; M306-T310 PolarHBondContact O-OG1 3Å
307	G	44.9	Very low	54.3	Low	36 Å²	36	93.3 Å²	93.3	37%	0.371	46%	0.462	S	S	.	.	H	α-helix	trans	-62.3	-33.7	178.1	0	0	0	0	0	114.2	S303 I304 R311	S303-G307 PolarHBondContact O-N 3.18Å; I304-G307 PolarHBondContact O-N 1.99Å; G307-R311 WeakPolarHBondContact O-CG 3.37Å
308	F	44.4	Very low	56.3	Low	156 Å²	156	87.8 Å²	87.8	68%	0.684	44%	0.438	S	S	*	.	H	α-helix	trans	-76.9	-38.9	175.8	-138.6	-88.3	0	0	0	112	I304 D305 M306 R311	I304-F308 PolarHBondContact O-N 3.01Å; D305-F308 PolarHBondContact O-N 2.67Å; M306-F308 VanDerWaalsContact C-N 3.31Å; M306-F308 PolarHBondContact O-N 3.33Å; F308-R311 PolarHBondContact O-N 3.47Å
309	K	51.1	Low	58.2	Low	102 Å²	102	77.8 Å²	77.8	44%	0.443	40%	0.401	S	S	.	.	H	α-helix	trans	-64.6	-39.1	173.4	-87.4	171.4	175.8	154.2	0	112.9	D305 M306 R311 A312 F313	D305-K309 WeakPolarHBondContact O-CB 3.42Å; D305-K309 PolarHBondContact O-N 3.28Å; D305-K309 IonicContact OD1-NZ 3.88Å; D305-K309 IonicContact OD2-NZ 2.76Å; D305-K309 PolarHBondContact OD2-NZ 3.22Å; M306-K309 HydrophobicContact CE-CD 4.34Å; M306-K309 PolarHBondContact O-N 3.43Å; K309-R311 VanDerWaalsContact C-N 3.34Å; K309-R311 PolarHBondContact O-N 3.43Å; K309-A312 PolarHBondContact O-N 3.33Å; K309-F313 PolarHBondContact O-N 3.07Å; K309-F313 VanDerWaalsContact O-N 3.14Å
310	T	54.3	Low	60.3	Low	57 Å²	57	73.8 Å²	73.8	35%	0.35	37%	0.373	S	S	.	.	H	α-helix	trans	-63.7	-36.8	177.6	-55.5	0	0	0	0	111.9	M306 F313 T314	M306-T310 WeakPolarHBondContact O-CB 3.28Å; M306-T310 PolarHBondContact O-N 3.09Å; M306-T310 PolarHBondContact O-OG1 3Å; T310-F313 WeakPolarHBondContact O-CB 3.33Å; T310-F313 PolarHBondContact O-N 3.12Å; T310-T314 PolarHBondContact O-N 2.96Å; T310-T314 PolarHBondContact O-OG1 3.34Å
311	R	59.8	Low	62.7	Low	174 Å²	174	68.7 Å²	68.7	66%	0.657	36%	0.359	S	S	*	.	H	α-helix	trans	-66.7	-40.1	179.4	-71.3	173.7	-175.5	-174.3	1.1	113.3	G307 F308 K309 T315 R374	G307-R311 WeakPolarHBondContact O-CG 3.37Å; F308-R311 PolarHBondContact O-N 3.47Å; K309-R311 VanDerWaalsContact C-N 3.34Å; K309-R311 PolarHBondContact O-N 3.43Å; R311-T315 PolarHBondContact O-N 3.3Å; R311-T315 PolarHBondContact O-OG1 3.16Å; R311-R374 PolarHBondContact O-NH2 2.96Å
312	A	62.2	Low	65.2	Low	42 Å²	42	62 Å²	62	35%	0.347	33%	0.33	S	S	.	.	H	α-helix	trans	-66.2	-42.3	174.8	0	0	0	0	0	111	K309 T315 I316	K309-A312 PolarHBondContact O-N 3.33Å; A312-T315 WeakPolarHBondContact O-CB 3.42Å; A312-T315 PolarHBondContact O-N 3.15Å; A312-T315 VanDerWaalsContact O-N 3.17Å; A312-I316 PolarHBondContact O-N 2.83Å
313	F	69.2	Low	67.5	Low	12 Å²	12	55.7 Å²	55.7	5%	0.053	30%	0.299	C	S	.	.	H	α-helix	trans	-59.5	-48.1	174.4	167.7	-99.1	0	0	0	112.9	F262 I265 L266 L269 K309 T310 T315 I316 L317	F262-F313 AromaticContact CD1-CE2 3.57Å; F262-F313 HydrophobicContact CD1-CE2 3.57Å; F262-F313 AromaticContact CD1-CZ 3.98Å; F262-F313 HydrophobicContact CD1-CZ 3.98Å; F262-F313 HydrophobicContact CE1-CD2 4.47Å; F262-F313 AromaticContact CE1-CE2 3.91Å; F262-F313 HydrophobicContact CE1-CE2 3.91Å; F262-F313 HydrophobicContact CE1-CZ 4.47Å; I265-F313 HydrophobicContact CB-CD2 4.29Å; I265-F313 HydrophobicContact CB-CE2 3.75Å; I265-F313 HydrophobicContact CD1-CD2 4.36Å; I265-F313 HydrophobicContact CD1-CE2 4.14Å; I265-F313 HydrophobicContact CG2-CD2 3.35Å; I265-F313 HydrophobicContact CG2-CE2 3.2Å; I265-F313 HydrophobicContact CG2-CG 4.23Å; I265-F313 HydrophobicContact CG2-CZ 4.03Å; L266-F313 HydrophobicContact CD2-CE1 3.54Å; L266-F313 HydrophobicContact CD2-CZ 3.45Å; L266-F313 VanDerWaalsContact CD2-CZ 3.45Å; L266-F313 HydrophobicContact CG-CE1 4.4Å; L266-F313 HydrophobicContact CG-CZ 3.8Å; L269-F313 HydrophobicContact CD1-CD1 3.98Å; L269-F313 HydrophobicContact CD1-CE1 4.2Å; L269-F313 HydrophobicContact CD1-CG 4.18Å; K309-F313 PolarHBondContact O-N 3.07Å; K309-F313 VanDerWaalsContact O-N 3.14Å; T310-F313 WeakPolarHBondContact O-CB 3.33Å; T310-F313 PolarHBondContact O-N 3.12Å; F313-T315 PolarHBondContact O-N 3.01Å; F313-T315 VanDerWaalsContact O-N 3.09Å; F313-I316 PolarHBondContact O-N 3.27Å; F313-L317 HydrophobicContact CE1-CD2 4.43Å; F313-L317 PolarHBondContact O-N 3.31Å
314	T	75.2	Confident	70	Confident	50 Å²	50	55.1 Å²	55.1	31%	0.307	29%	0.291	S	S	.	.	H	α-helix	trans	-62	-22.3	178.8	-54.1	0	0	0	0	111.6	T310 I318 R374	T310-T314 PolarHBondContact O-N 2.96Å; T310-T314 PolarHBondContact O-OG1 3.34Å; T314-I318 WeakPolarHBondContact O-CG1 3.34Å; T314-I318 PolarHBondContact O-N 2.9Å; T314-R374 VanDerWaalsContact C-NH2 3.27Å; T314-R374 PolarHBondContact O-NH1 3.23Å
315	T	79.6	Confident	72.4	Confident	8 Å²	8	54.1 Å²	54.1	5%	0.049	29%	0.29	C	S	.	.	H	α-helix	trans	-71.4	-44.2	174.8	-51.5	0	0	0	0	110.5	R311 A312 F313 I318 L319 I370 R374 I375	R311-T315 PolarHBondContact O-N 3.3Å; R311-T315 PolarHBondContact O-OG1 3.16Å; A312-T315 WeakPolarHBondContact O-CB 3.42Å; A312-T315 PolarHBondContact O-N 3.15Å; A312-T315 VanDerWaalsContact O-N 3.17Å; F313-T315 PolarHBondContact O-N 3.01Å; F313-T315 VanDerWaalsContact O-N 3.09Å; T315-I318 PolarHBondContact O-N 3.08Å; T315-L319 WeakPolarHBondContact O-CG 3.48Å; T315-L319 PolarHBondContact O-N 3.48Å; T315-I370 HydrophobicContact CG2-CG2 4.05Å; T315-R374 HydrophobicContact CG2-CB 3.67Å; T315-R374 HydrophobicContact CG2-CG 4.22Å; T315-R374 VanDerWaalsContact N-NH2 3.19Å; T315-R374 WeakPolarHBondContact OG1-CB 3.24Å; T315-R374 PolarHBondContact OG1-NH2 3.13Å; T315-I375 HydrophobicContact CG2-CG1 4.47Å
316	I	78.6	Confident	74.7	Confident	17 Å²	17	50.9 Å²	50.9	9%	0.087	27%	0.272	C	S	.	.	H	α-helix	trans	-68.8	-37.6	-179.5	-61.7	157.8	0	0	0	110.6	I175 R179 F262 A312 F313 I318 L319 F320	I175-I316 HydrophobicContact CG2-CD1 4.33Å; I175-I316 HydrophobicContact CG2-CG1 4.31Å; I175-I316 HydrophobicContact CG2-CG2 4.45Å; R179-I316 HydrophobicContact CB-CD1 4.49Å; R179-I316 HydrophobicContact CG-CD1 3.49Å; R179-I316 VanDerWaalsContact CG-CD1 3.49Å; F262-I316 HydrophobicContact CE1-CB 4.31Å; F262-I316 HydrophobicContact CE1-CG2 3.79Å; F262-I316 HydrophobicContact CZ-CB 4.26Å; F262-I316 HydrophobicContact CZ-CG2 3.43Å; F262-I316 VanDerWaalsContact CZ-CG2 3.43Å; F262-I316 WeakPolarHBondContact CZ-O 3.22Å; A312-I316 PolarHBondContact O-N 2.83Å; F313-I316 PolarHBondContact O-N 3.27Å; I316-I318 VanDerWaalsContact C-N 3.34Å; I316-I318 PolarHBondContact O-N 3.36Å; I316-L319 PolarHBondContact O-N 3.34Å; I316-F320 PolarHBondContact O-N 3.26Å
317	L	83.3	Confident	76.9	Confident	61 Å²	61	48.7 Å²	48.7	32%	0.319	26%	0.261	S	S	.	.	H	α-helix	trans	-60	-42.7	172	-176.2	66.6	0	0	0	112.1	F262 F313 F320 A321	F262-L317 HydrophobicContact CD1-CD1 4.11Å; F262-L317 HydrophobicContact CE1-CB 4.15Å; F262-L317 HydrophobicContact CE1-CD1 4.3Å; F262-L317 HydrophobicContact CG-CD1 4.37Å; F313-L317 HydrophobicContact CE1-CD2 4.43Å; F313-L317 PolarHBondContact O-N 3.31Å; L317-F320 PolarHBondContact O-N 3.47Å; L317-A321 WeakPolarHBondContact O-CB 3.4Å; L317-A321 PolarHBondContact O-N 3.25Å
318	I	88.6	Confident	79.3	Confident	67 Å²	67	48 Å²	48	34%	0.344	25%	0.252	S	S	.	.	H	α-helix	trans	-63.9	-45.1	175.5	-70.8	-169.7	0	0	0	110.8	T314 T315 I316 F320 A321 V322 I370	T314-I318 WeakPolarHBondContact O-CG1 3.34Å; T314-I318 PolarHBondContact O-N 2.9Å; T315-I318 PolarHBondContact O-N 3.08Å; I316-I318 VanDerWaalsContact C-N 3.34Å; I316-I318 PolarHBondContact O-N 3.36Å; I318-F320 PolarHBondContact O-N 3.34Å; I318-A321 PolarHBondContact O-N 3.29Å; I318-V322 HydrophobicContact CG2-CG2 4.26Å; I318-V322 WeakPolarHBondContact O-CG2 3.5Å; I318-V322 PolarHBondContact O-N 2.95Å; I318-I370 HydrophobicContact CG2-CD1 4.04Å; I318-I370 HydrophobicContact CG2-CG1 4.17Å; I318-I370 HydrophobicContact CG2-CG2 4.17Å
319	L	87.2	Confident	81.7	Confident	7 Å²	7	42.9 Å²	42.9	4%	0.037	24%	0.235	C	C	.	.	H	α-helix	trans	-58.2	-39.5	177.6	-66.4	168	0	0	0	111.7	L172 T315 I316 F323 I370 Y371	L172-L319 HydrophobicContact CD2-CB 4.33Å; T315-L319 WeakPolarHBondContact O-CG 3.48Å; T315-L319 PolarHBondContact O-N 3.48Å; I316-L319 PolarHBondContact O-N 3.34Å; L319-F323 WeakPolarHBondContact O-CB 3.22Å; L319-F323 PolarHBondContact O-N 3.44Å; L319-I370 HydrophobicContact CD2-CB 4.2Å; L319-I370 HydrophobicContact CD2-CD1 3.87Å; L319-I370 HydrophobicContact CD2-CG2 3.83Å; L319-I370 HydrophobicContact CG-CG2 4.21Å; L319-Y371 HydrophobicContact CD1-CE1 3.77Å; L319-Y371 HydrophobicContact CD2-CE1 3.76Å; L319-Y371 HydrophobicContact CG-CE1 4.37Å
320	F	86.7	Confident	83.7	Confident	15 Å²	15	38.1 Å²	38.1	7%	0.066	21%	0.214	C	C	.	.	H	α-helix	trans	-69.1	-42.8	176	178.6	-127.3	0	0	0	113.2	F255 I258 L259 F262 I316 L317 I318 V322 F323 I324	F255-F320 HydrophobicContact CD2-CE2 4.25Å; F255-F320 AromaticContact CD2-CZ 3.91Å; F255-F320 HydrophobicContact CD2-CZ 3.91Å; F255-F320 HydrophobicContact CE2-CZ 4.22Å; I258-F320 HydrophobicContact CB-CD2 4.03Å; I258-F320 HydrophobicContact CB-CE2 3.65Å; I258-F320 HydrophobicContact CB-CZ 4.04Å; I258-F320 HydrophobicContact CD1-CD2 4.28Å; I258-F320 HydrophobicContact CD1-CE2 4.29Å; I258-F320 HydrophobicContact CG2-CB 4.28Å; I258-F320 HydrophobicContact CG2-CD1 4Å; I258-F320 HydrophobicContact CG2-CD2 3.24Å; I258-F320 HydrophobicContact CG2-CE1 4.05Å; I258-F320 HydrophobicContact CG2-CE2 3.32Å; I258-F320 HydrophobicContact CG2-CG 3.59Å; I258-F320 HydrophobicContact CG2-CZ 3.72Å; L259-F320 HydrophobicContact CB-CZ 4.25Å; F262-F320 HydrophobicContact CD2-CB 4.3Å; F262-F320 AromaticContact CD2-CD1 3.45Å; F262-F320 HydrophobicContact CD2-CD1 3.45Å; F262-F320 VanDerWaalsContact CD2-CD1 3.45Å; F262-F320 AromaticContact CD2-CE1 3.84Å; F262-F320 HydrophobicContact CD2-CE1 3.84Å; F262-F320 AromaticContact CD2-CG 3.94Å; F262-F320 HydrophobicContact CD2-CG 3.94Å; F262-F320 HydrophobicContact CE2-CB 3.36Å; F262-F320 AromaticContact CE2-CD1 3.41Å; F262-F320 HydrophobicContact CE2-CD1 3.41Å; F262-F320 VanDerWaalsContact CE2-CD1 3.41Å; F262-F320 HydrophobicContact CE2-CD2 4.25Å; F262-F320 HydrophobicContact CE2-CE1 4.19Å; F262-F320 AromaticContact CE2-CG 3.42Å; F262-F320 HydrophobicContact CE2-CG 3.42Å; F262-F320 VanDerWaalsContact CE2-CG 3.42Å; F262-F320 HydrophobicContact CZ-CB 3.81Å; F262-F320 HydrophobicContact CZ-CD1 4.43Å; F262-F320 HydrophobicContact CZ-CG 4.34Å; I316-F320 PolarHBondContact O-N 3.26Å; L317-F320 PolarHBondContact O-N 3.47Å; I318-F320 PolarHBondContact O-N 3.34Å; F320-V322 VanDerWaalsContact C-N 3.31Å; F320-V322 PolarHBondContact O-N 2.85Å; F320-F323 HydrophobicContact CD2-CD1 4.11Å; F320-F323 HydrophobicContact CE2-CD1 4.25Å; F320-F323 WeakPolarHBondContact O-CB 3.5Å; F320-F323 PolarHBondContact O-N 2.94Å; F320-I324 HydrophobicContact CD1-CD1 3.89Å; F320-I324 HydrophobicContact CD2-CD1 4.15Å; F320-I324 HydrophobicContact CD2-CG1 4.25Å; F320-I324 HydrophobicContact CE1-CD1 3.5Å; F320-I324 VanDerWaalsContact CE1-CD1 3.5Å; F320-I324 HydrophobicContact CE2-CD1 3.77Å; F320-I324 HydrophobicContact CE2-CG1 3.9Å; F320-I324 HydrophobicContact CG-CD1 4.22Å; F320-I324 HydrophobicContact CZ-CD1 3.45Å; F320-I324 VanDerWaalsContact CZ-CD1 3.45Å; F320-I324 HydrophobicContact CZ-CG1 4.07Å; F320-I324 WeakPolarHBondContact O-CG1 3.41Å; F320-I324 PolarHBondContact O-N 3.31Å
321	A	91.1	Very high	85.5	Confident	48 Å²	48	35.4 Å²	35.4	40%	0.397	20%	0.197	S	C	.	.	H	α-helix	trans	-60.2	-43.8	175.4	0	0	0	0	0	111.3	L317 I318 I324 V325	L317-A321 WeakPolarHBondContact O-CB 3.4Å; L317-A321 PolarHBondContact O-N 3.25Å; I318-A321 PolarHBondContact O-N 3.29Å; A321-I324 PolarHBondContact O-N 2.94Å; A321-V325 WeakPolarHBondContact O-CG2 3.28Å; A321-V325 PolarHBondContact O-N 3.46Å
322	V	92.9	Very high	87.1	Confident	24 Å²	24	30.4 Å²	30.4	15%	0.145	19%	0.186	C	C	.	.	H	α-helix	trans	-63	-42	174.8	171.7	0	0	0	0	111	I318 F320 I324 V325 C326 K363 L366 I370	I318-V322 HydrophobicContact CG2-CG2 4.26Å; I318-V322 WeakPolarHBondContact O-CG2 3.5Å; I318-V322 PolarHBondContact O-N 2.95Å; F320-V322 VanDerWaalsContact C-N 3.31Å; F320-V322 PolarHBondContact O-N 2.85Å; V322-I324 PolarHBondContact O-N 3.09Å; V322-V325 PolarHBondContact O-N 3.24Å; V322-C326 VanDerWaalsContact O-CB 3.22Å; V322-C326 WeakPolarHBondContact O-CB 3.36Å; V322-C326 PolarHBondContact O-N 3.36Å; V322-C326 PolarHBondContact O-SG 3.42Å; V322-K363 HydrophobicContact CG1-CG 4.36Å; V322-L366 HydrophobicContact CG1-CB 4.31Å; V322-L366 HydrophobicContact CG1-CD1 3.82Å; V322-I370 HydrophobicContact CG2-CD1 3.98Å
323	F	90.8	Very high	88.6	Confident	2 Å²	2	29.7 Å²	29.7	1%	0.009	18%	0.175	C	C	.	.	H	α-helix	trans	-55.9	-50.4	173.3	168.5	-104.5	0	0	0	111.8	V169 L172 S250 F251 L319 F320 C326 W327	V169-F323 HydrophobicContact CG1-CZ 4.31Å; V169-F323 HydrophobicContact CG2-CD2 4.17Å; V169-F323 HydrophobicContact CG2-CE2 3.35Å; V169-F323 HydrophobicContact CG2-CZ 3.91Å; L172-F323 HydrophobicContact CD1-CB 4.2Å; L172-F323 HydrophobicContact CD1-CD2 4.28Å; L172-F323 HydrophobicContact CD1-CG 4.34Å; S250-F323 WeakPolarHBondContact O-CZ 3.46Å; F251-F323 HydrophobicContact CD2-CE1 4.05Å; F251-F323 AromaticContact CD2-CZ 3.88Å; F251-F323 HydrophobicContact CD2-CZ 3.88Å; F251-F323 HydrophobicContact CE2-CE1 4.28Å; L319-F323 WeakPolarHBondContact O-CB 3.22Å; L319-F323 PolarHBondContact O-N 3.44Å; F320-F323 HydrophobicContact CD2-CD1 4.11Å; F320-F323 HydrophobicContact CE2-CD1 4.25Å; F320-F323 WeakPolarHBondContact O-CB 3.5Å; F320-F323 PolarHBondContact O-N 2.94Å; F323-C326 PolarHBondContact O-N 3.36Å; F323-W327 HydrophobicContact CD2-CB 4.24Å; F323-W327 AromaticContact CD2-CD1 3.38Å; F323-W327 AromaticContact CD2-CG 3.92Å; F323-W327 HydrophobicContact CD2-CG 3.92Å; F323-W327 HydrophobicContact CE2-CB 3.87Å; F323-W327 AromaticContact CE2-CD1 3.56Å; F323-W327 HydrophobicContact CE2-CD2 4.45Å; F323-W327 AromaticContact CE2-CG 3.64Å; F323-W327 HydrophobicContact CE2-CG 3.64Å; F323-W327 HydrophobicContact CZ-CB 4.32Å; F323-W327 VanDerWaalsContact O-CB 3.27Å; F323-W327 WeakPolarHBondContact O-CB 3.25Å; F323-W327 PolarHBondContact O-N 3.48Å
324	I	93.1	Very high	89.6	Confident	45 Å²	45	29.4 Å²	29.4	23%	0.231	17%	0.174	C	C	.	.	H	α-helix	trans	-60.7	-52.7	179.9	-66.4	161.6	0	0	0	111.1	F255 F320 A321 V322 C326 W327 A328	F255-I324 HydrophobicContact CD2-CD1 4Å; F255-I324 HydrophobicContact CD2-CG1 3.86Å; F255-I324 HydrophobicContact CE2-CD1 3.72Å; F255-I324 HydrophobicContact CE2-CG1 3.98Å; F320-I324 HydrophobicContact CD1-CD1 3.89Å; F320-I324 HydrophobicContact CD2-CD1 4.15Å; F320-I324 HydrophobicContact CD2-CG1 4.25Å; F320-I324 HydrophobicContact CE1-CD1 3.5Å; F320-I324 VanDerWaalsContact CE1-CD1 3.5Å; F320-I324 HydrophobicContact CE2-CD1 3.77Å; F320-I324 HydrophobicContact CE2-CG1 3.9Å; F320-I324 HydrophobicContact CG-CD1 4.22Å; F320-I324 HydrophobicContact CZ-CD1 3.45Å; F320-I324 VanDerWaalsContact CZ-CD1 3.45Å; F320-I324 HydrophobicContact CZ-CG1 4.07Å; F320-I324 WeakPolarHBondContact O-CG1 3.41Å; F320-I324 PolarHBondContact O-N 3.31Å; A321-I324 PolarHBondContact O-N 2.94Å; V322-I324 PolarHBondContact O-N 3.09Å; I324-C326 PolarHBondContact O-N 2.94Å; I324-W327 PolarHBondContact O-N 2.9Å; I324-A328 HydrophobicContact CG2-CB 4.24Å; I324-A328 WeakPolarHBondContact O-CB 3.35Å; I324-A328 PolarHBondContact O-N 3.44Å
325	V	94.6	Very high	90.5	Very high	91 Å²	91	28.9 Å²	28.9	55%	0.552	17%	0.169	S	C	*	.	H	α-helix	trans	-59.3	-39.8	-176.8	171	0	0	0	0	110.5	A321 V322 P329 L359	A321-V325 WeakPolarHBondContact O-CG2 3.28Å; A321-V325 PolarHBondContact O-N 3.46Å; V322-V325 PolarHBondContact O-N 3.24Å; V325-P329 VanDerWaalsContact O-CD 3.25Å; V325-P329 WeakPolarHBondContact O-CD 3.33Å; V325-P329 WeakPolarHBondContact O-CG 3.31Å; V325-L359 WeakPolarHBondContact O-CD2 3.23Å
326	C	94.2	Very high	91.2	Very high	4 Å²	4	31.4 Å²	31.4	3%	0.027	18%	0.184	C	C	.	.	H	α-helix	trans	-81	-28.6	-177.7	-67.5	0	0	0	0	115	V322 F323 I324 L359 C360 K363	V322-C326 VanDerWaalsContact O-CB 3.22Å; V322-C326 WeakPolarHBondContact O-CB 3.36Å; V322-C326 PolarHBondContact O-N 3.36Å; V322-C326 PolarHBondContact O-SG 3.42Å; F323-C326 PolarHBondContact O-N 3.36Å; I324-C326 PolarHBondContact O-N 2.94Å; C326-L359 HydrophobicContact CB-CG 4.35Å; C326-L359 WeakPolarHBondContact CB-O 3.17Å; C326-L359 PolarHBondContact SG-O 3.49Å; C326-C360 PolarHBondContact O-SG 3.13Å; C326-K363 HydrophobicContact CB-CB 3.85Å
327	W	93.4	Very high	91.8	Very high	4 Å²	4	30.6 Å²	30.6	2%	0.015	18%	0.18	C	C	.	.	H	α-helix	trans	-106.9	-33.3	-172.7	-79.9	91.8	0	0	0	115.3	F161 W162 V165 F251 F323 I324 F330 T331 C360	F161-W327 HydrophobicContact CE1-CH2 4.01Å; F161-W327 HydrophobicContact CE1-CZ3 4.33Å; F161-W327 HydrophobicContact CE2-CH2 4.41Å; F161-W327 AromaticContact CZ-CH2 3.63Å; F161-W327 HydrophobicContact CZ-CH2 3.63Å; F161-W327 HydrophobicContact CZ-CZ3 4.23Å; W162-W327 HydrophobicContact CZ3-CZ3 4.28Å; V165-W327 HydrophobicContact CB-CH2 3.8Å; V165-W327 HydrophobicContact CB-CZ2 4.07Å; V165-W327 HydrophobicContact CB-CZ3 4.43Å; V165-W327 HydrophobicContact CG1-CD2 4.39Å; V165-W327 HydrophobicContact CG1-CE3 4.05Å; V165-W327 HydrophobicContact CG1-CH2 3.26Å; V165-W327 HydrophobicContact CG1-CZ2 3.59Å; V165-W327 HydrophobicContact CG1-CZ3 3.47Å; V165-W327 VanDerWaalsContact CG1-CZ3 3.47Å; V165-W327 HydrophobicContact CG2-CH2 3.12Å; V165-W327 HydrophobicContact CG2-CZ2 3.41Å; V165-W327 VanDerWaalsContact CG2-CZ2 3.41Å; V165-W327 HydrophobicContact CG2-CZ3 4.11Å; F251-W327 HydrophobicContact CD2-CB 4Å; F251-W327 HydrophobicContact CE2-CB 4.36Å; F323-W327 HydrophobicContact CD2-CB 4.24Å; F323-W327 AromaticContact CD2-CD1 3.38Å; F323-W327 AromaticContact CD2-CG 3.92Å; F323-W327 HydrophobicContact CD2-CG 3.92Å; F323-W327 HydrophobicContact CE2-CB 3.87Å; F323-W327 AromaticContact CE2-CD1 3.56Å; F323-W327 HydrophobicContact CE2-CD2 4.45Å; F323-W327 AromaticContact CE2-CG 3.64Å; F323-W327 HydrophobicContact CE2-CG 3.64Å; F323-W327 HydrophobicContact CZ-CB 4.32Å; F323-W327 VanDerWaalsContact O-CB 3.27Å; F323-W327 WeakPolarHBondContact O-CB 3.25Å; F323-W327 PolarHBondContact O-N 3.48Å; I324-W327 PolarHBondContact O-N 2.9Å; W327-F330 HydrophobicContact CE3-CD1 4.33Å; W327-F330 AromaticContact CZ3-CD1 3.88Å; W327-F330 HydrophobicContact CZ3-CD1 3.88Å; W327-F330 HydrophobicContact CZ3-CE1 4.28Å; W327-F330 PolarHBondContact O-N 3.45Å; W327-T331 WeakPolarHBondContact O-CB 3.27Å; W327-T331 PolarHBondContact O-N 2.96Å; W327-T331 PolarHBondContact O-OG1 2.75Å; W327-C360 HydrophobicContact CH2-CB 4.06Å; W327-C360 HydrophobicContact CZ2-CB 3.89Å
328	A	94.4	Very high	92.2	Very high	22 Å²	22	27.7 Å²	27.7	18%	0.182	17%	0.165	C	C	.	.	H	α-helix	trans	-58.5	-44.9	-177.3	0	0	0	0	0	112.4	F251 I324 T332	F251-A328 HydrophobicContact CE1-CB 4.11Å; F251-A328 HydrophobicContact CE2-CB 3.58Å; F251-A328 HydrophobicContact CZ-CB 3.26Å; I324-A328 HydrophobicContact CG2-CB 4.24Å; I324-A328 WeakPolarHBondContact O-CB 3.35Å; I324-A328 PolarHBondContact O-N 3.44Å; A328-T332 WeakPolarHBondContact O-CB 3.14Å; A328-T332 PolarHBondContact O-N 2.9Å; A328-T332 PolarHBondContact O-OG1 3.04Å
329	P	95.1	Very high	92.5	Very high	48 Å²	48	29 Å²	29	31%	0.312	17%	0.168	S	C	.	.	H	α-helix	trans	-62.6	-50	179.3	-25	37.8	0	0	0	111.9	V325 T331 T332 Y333 L356 L359	V325-P329 VanDerWaalsContact O-CD 3.25Å; V325-P329 WeakPolarHBondContact O-CD 3.33Å; V325-P329 WeakPolarHBondContact O-CG 3.31Å; P329-T331 PolarHBondContact O-N 3.39Å; P329-T332 PolarHBondContact O-N 2.97Å; P329-Y333 WeakPolarHBondContact O-CB 3.44Å; P329-Y333 PolarHBondContact O-N 2.94Å; P329-L356 HydrophobicContact CB-CD1 4.44Å; P329-L356 HydrophobicContact CB-CD2 3.54Å; P329-L359 HydrophobicContact CG-CD2 4.32Å
330	F	92.7	Very high	92.7	Very high	3 Å²	3	30.6 Å²	30.6	1%	0.013	18%	0.18	C	C	.	.	H	α-helix	trans	-63.1	-41.8	-177.8	-179.9	-98.4	0	0	0	112.7	F161 W162 W327 Y333 S334 L356 L357 C360	F161-F330 AromaticContact CE1-CE1 3.77Å; F161-F330 HydrophobicContact CE1-CE1 3.77Å; F161-F330 HydrophobicContact CE1-CZ 4.02Å; F161-F330 HydrophobicContact CZ-CE1 4.02Å; F161-F330 HydrophobicContact CZ-CZ 4.15Å; W162-F330 HydrophobicContact CH2-CD1 4.49Å; W162-F330 AromaticContact CH2-CE1 3.86Å; W162-F330 HydrophobicContact CH2-CE1 3.86Å; W162-F330 AromaticContact CZ2-CE1 3.89Å; W162-F330 HydrophobicContact CZ2-CE1 3.89Å; W327-F330 HydrophobicContact CE3-CD1 4.33Å; W327-F330 AromaticContact CZ3-CD1 3.88Å; W327-F330 HydrophobicContact CZ3-CD1 3.88Å; W327-F330 HydrophobicContact CZ3-CE1 4.28Å; W327-F330 PolarHBondContact O-N 3.45Å; F330-Y333 PolarHBondContact O-N 3.22Å; F330-S334 WeakPolarHBondContact O-CB 3.46Å; F330-S334 PolarHBondContact O-N 2.94Å; F330-S334 PolarHBondContact O-OG 2.99Å; F330-L356 HydrophobicContact CB-CB 4.19Å; F330-L356 HydrophobicContact CD2-CB 4.06Å; F330-L357 HydrophobicContact CE2-CB 4.34Å; F330-C360 WeakPolarHBondContact CB-SG 3.34Å
331	T	93.4	Very high	92.9	Very high	0 Å²	0	35.8 Å²	35.8	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-66.1	-48.1	179.5	-52.5	0	0	0	0	110.8	F251 F252 W327 P329 Y333 S334 L335	F251-T331 HydrophobicContact CB-CG2 3.83Å; F251-T331 HydrophobicContact CD1-CG2 4.35Å; F251-T331 HydrophobicContact CG-CG2 4.26Å; F252-T331 HydrophobicContact CE2-CG2 4.37Å; W327-T331 WeakPolarHBondContact O-CB 3.27Å; W327-T331 PolarHBondContact O-N 2.96Å; W327-T331 PolarHBondContact O-OG1 2.75Å; P329-T331 PolarHBondContact O-N 3.39Å; T331-Y333 VanDerWaalsContact C-N 3.31Å; T331-Y333 PolarHBondContact O-N 3.49Å; T331-S334 PolarHBondContact O-N 3.44Å; T331-L335 WeakPolarHBondContact O-CB 3.33Å; T331-L335 PolarHBondContact O-N 3.31Å
332	T	93.6	Very high	92.9	Very high	68 Å²	68	40.3 Å²	40.3	42%	0.417	22%	0.215	S	C	.	.	H	α-helix	trans	-62	-43.3	178.8	-52.4	0	0	0	0	110.6	A328 P329 L335 V336	A328-T332 WeakPolarHBondContact O-CB 3.14Å; A328-T332 PolarHBondContact O-N 2.9Å; A328-T332 PolarHBondContact O-OG1 3.04Å; P329-T332 PolarHBondContact O-N 2.97Å; T332-L335 PolarHBondContact O-N 2.98Å; T332-V336 HydrophobicContact CG2-CG2 4.48Å; T332-V336 WeakPolarHBondContact O-CG2 3.29Å; T332-V336 PolarHBondContact O-N 2.99Å
333	Y	92.8	Very high	92.8	Very high	28 Å²	28	41.7 Å²	41.7	11%	0.11	22%	0.219	C	C	.	.	H	α-helix	trans	-62	-46.2	179	-161.7	-96.8	0	0	0	112.3	P329 F330 T331 L335 V336 A337 F343 F349 I352 L356	P329-Y333 WeakPolarHBondContact O-CB 3.44Å; P329-Y333 PolarHBondContact O-N 2.94Å; F330-Y333 PolarHBondContact O-N 3.22Å; T331-Y333 VanDerWaalsContact C-N 3.31Å; T331-Y333 PolarHBondContact O-N 3.49Å; Y333-L335 VanDerWaalsContact C-N 3.33Å; Y333-L335 PolarHBondContact O-N 3.24Å; Y333-V336 PolarHBondContact O-N 2.95Å; Y333-A337 VanDerWaalsContact O-CB 3.28Å; Y333-A337 WeakPolarHBondContact O-CB 3.34Å; Y333-A337 PolarHBondContact O-N 3.31Å; Y333-F343 HydrophobicContact CD1-CE1 4.38Å; Y333-F343 AromaticContact CD2-CE1 3.9Å; Y333-F343 HydrophobicContact CD2-CE1 3.9Å; Y333-F343 AromaticContact CD2-CZ 3.56Å; Y333-F343 HydrophobicContact CD2-CZ 3.56Å; Y333-F343 HydrophobicContact CE1-CE1 4.14Å; Y333-F343 AromaticContact CE2-CE1 3.64Å; Y333-F343 HydrophobicContact CE2-CE1 3.64Å; Y333-F343 HydrophobicContact CE2-CE2 4.27Å; Y333-F343 AromaticContact CE2-CZ 3.23Å; Y333-F343 HydrophobicContact CE2-CZ 3.23Å; Y333-F343 HydrophobicContact CG-CE1 4.24Å; Y333-F343 HydrophobicContact CG-CZ 4.34Å; Y333-F343 AromaticContact CZ-CE1 3.74Å; Y333-F343 AromaticContact CZ-CZ 3.78Å; Y333-F349 AromaticContact CD1-CE2 3.93Å; Y333-F349 HydrophobicContact CD1-CE2 3.93Å; Y333-F349 HydrophobicContact CD1-CZ 4.35Å; Y333-F349 AromaticContact CE1-CD2 3.5Å; Y333-F349 HydrophobicContact CE1-CD2 3.5Å; Y333-F349 VanDerWaalsContact CE1-CD2 3.5Å; Y333-F349 AromaticContact CE1-CE2 3.19Å; Y333-F349 HydrophobicContact CE1-CE2 3.19Å; Y333-F349 HydrophobicContact CE1-CG 4.28Å; Y333-F349 AromaticContact CE1-CZ 3.77Å; Y333-F349 HydrophobicContact CE1-CZ 3.77Å; Y333-F349 AromaticContact CZ-CD2 3.59Å; Y333-F349 AromaticContact CZ-CE2 3.74Å; Y333-F349 VanDerWaalsContact OH-CA 3.24Å; Y333-F349 WeakPolarHBondContact OH-CA 3.36Å; Y333-F349 WeakPolarHBondContact OH-CD2 3.15Å; Y333-F349 PolarHBondContact OH-O 2.81Å; Y333-I352 HydrophobicContact CD2-CG2 4.1Å; Y333-I352 HydrophobicContact CE1-CG2 4.45Å; Y333-I352 HydrophobicContact CE2-CB 4.15Å; Y333-I352 HydrophobicContact CE2-CG2 3.48Å; Y333-I352 VanDerWaalsContact CE2-CG2 3.48Å; Y333-L356 HydrophobicContact CD1-CD1 3.94Å; Y333-L356 HydrophobicContact CD2-CD1 3.67Å; Y333-L356 HydrophobicContact CE2-CD1 4.43Å; Y333-L356 HydrophobicContact CG-CD1 3.39Å
334	S	90.8	Very high	92.6	Very high	5 Å²	5	41.8 Å²	41.8	4%	0.035	22%	0.22	C	C	.	.	H	α-helix	trans	-65	-37.1	177.2	-58.7	0	0	0	0	112.3	F330 T331 T338	F330-S334 WeakPolarHBondContact O-CB 3.46Å; F330-S334 PolarHBondContact O-N 2.94Å; F330-S334 PolarHBondContact O-OG 2.99Å; T331-S334 PolarHBondContact O-N 3.44Å; S334-T338 PolarHBondContact O-N 3.19Å; S334-T338 PolarHBondContact O-OG1 2.92Å
335	L	94	Very high	92.3	Very high	40 Å²	40	46 Å²	46	21%	0.209	23%	0.234	C	C	.	.	H	α-helix	trans	-65.3	-51.7	176.7	-169.7	68.9	0	0	0	110.6	V243 I244 F252 T331 T332 Y333 A337 T338 F339	V243-L335 HydrophobicContact CG1-CD1 4.19Å; I244-L335 HydrophobicContact CG1-CD1 4.24Å; F252-L335 HydrophobicContact CE2-CD2 4.23Å; F252-L335 HydrophobicContact CZ-CD2 4.37Å; T331-L335 WeakPolarHBondContact O-CB 3.33Å; T331-L335 PolarHBondContact O-N 3.31Å; T332-L335 PolarHBondContact O-N 2.98Å; Y333-L335 VanDerWaalsContact C-N 3.33Å; Y333-L335 PolarHBondContact O-N 3.24Å; L335-A337 VanDerWaalsContact C-N 3.3Å; L335-A337 PolarHBondContact O-N 3Å; L335-T338 WeakPolarHBondContact O-CB 3.24Å; L335-T338 PolarHBondContact O-N 3.48Å; L335-T338 VanDerWaalsContact O-N 3.09Å; L335-F339 HydrophobicContact CD1-CD2 4.46Å; L335-F339 HydrophobicContact CD1-CE2 3.8Å; L335-F339 HydrophobicContact CG-CD2 4.49Å; L335-F339 HydrophobicContact CG-CE2 4.27Å; L335-F339 VanDerWaalsContact O-CD2 3.22Å; L335-F339 WeakPolarHBondContact O-CD2 3.37Å; L335-F339 PolarHBondContact O-N 3.5Å
336	V	93.7	Very high	92	Very high	60 Å²	60	45.9 Å²	45.9	36%	0.364	23%	0.227	S	C	.	.	H	α-helix	trans	-60.6	-40.1	178.2	175.8	0	0	0	0	111.4	T332 Y333 T338 F339 S340 F343	T332-V336 HydrophobicContact CG2-CG2 4.48Å; T332-V336 WeakPolarHBondContact O-CG2 3.29Å; T332-V336 PolarHBondContact O-N 2.99Å; Y333-V336 PolarHBondContact O-N 2.95Å; V336-T338 PolarHBondContact O-N 2.92Å; V336-F339 PolarHBondContact O-N 3.28Å; V336-S340 WeakPolarHBondContact O-CB 3.42Å; V336-S340 PolarHBondContact O-N 3.37Å; V336-F343 HydrophobicContact CB-CD1 4.37Å; V336-F343 HydrophobicContact CB-CE1 4.19Å; V336-F343 HydrophobicContact CG1-CB 4.31Å; V336-F343 HydrophobicContact CG1-CD1 3.76Å; V336-F343 HydrophobicContact CG1-CD2 4.04Å; V336-F343 HydrophobicContact CG1-CE1 3.92Å; V336-F343 HydrophobicContact CG1-CE2 4.2Å; V336-F343 HydrophobicContact CG1-CG 3.79Å; V336-F343 HydrophobicContact CG1-CZ 4.11Å
337	A	90.9	Very high	91.4	Very high	0 Å²	0	50.9 Å²	50.9	0%	0	25%	0.25	C	S	.	.	H	α-helix	trans	-56.8	-35	175.9	0	0	0	0	0	113.2	Y233 Y333 L335 F343 Y344 F349	Y233-A337 VanDerWaalsContact CA-O 3.31Å; Y233-A337 WeakPolarHBondContact CA-O 3.49Å; Y233-A337 PolarHBondContact N-O 3.38Å; Y333-A337 VanDerWaalsContact O-CB 3.28Å; Y333-A337 WeakPolarHBondContact O-CB 3.34Å; Y333-A337 PolarHBondContact O-N 3.31Å; L335-A337 VanDerWaalsContact C-N 3.3Å; L335-A337 PolarHBondContact O-N 3Å; A337-F343 HydrophobicContact CB-CD1 4.35Å; A337-Y344 HydrophobicContact CB-CD2 4.25Å; A337-F349 HydrophobicContact CB-CE2 3.53Å; A337-F349 HydrophobicContact CB-CZ 3.6Å
338	T	92.4	Very high	91	Very high	0 Å²	0	54.5 Å²	54.5	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-71.7	-35.5	-177.7	-57.9	0	0	0	0	111.7	Y233 T234 Q240 V243 S334 L335 V336	Y233-T338 WeakPolarHBondContact CD2-O 3.42Å; T234-T338 HydrophobicContact CG2-CG2 3.83Å; T234-T338 PolarHBondContact N-O 3.08Å; Q240-T338 HydrophobicContact CG-CG2 4.14Å; V243-T338 HydrophobicContact CB-CG2 4.19Å; V243-T338 HydrophobicContact CG1-CG2 4.35Å; V243-T338 HydrophobicContact CG2-CG2 4.06Å; S334-T338 PolarHBondContact O-N 3.19Å; S334-T338 PolarHBondContact O-OG1 2.92Å; L335-T338 WeakPolarHBondContact O-CB 3.24Å; L335-T338 PolarHBondContact O-N 3.48Å; L335-T338 VanDerWaalsContact O-N 3.09Å; V336-T338 PolarHBondContact O-N 2.92Å
339	F	93.9	Very high	90.6	Very high	95 Å²	95	53.6 Å²	53.6	42%	0.417	26%	0.262	S	S	.	.	H	α-helix	trans	-96.4	-22	-175.9	-66.3	-75.9	0	0	0	114.5	Q240 I244 L335 V336	Q240-F339 HydrophobicContact CB-CE1 3.93Å; Q240-F339 HydrophobicContact CB-CZ 4.02Å; Q240-F339 HydrophobicContact CG-CD1 4.47Å; Q240-F339 HydrophobicContact CG-CE1 3.84Å; Q240-F339 HydrophobicContact CG-CZ 4.27Å; I244-F339 HydrophobicContact CD1-CE2 4.48Å; I244-F339 HydrophobicContact CD1-CZ 3.75Å; I244-F339 HydrophobicContact CG1-CE2 4.28Å; I244-F339 HydrophobicContact CG1-CZ 3.98Å; L335-F339 HydrophobicContact CD1-CD2 4.46Å; L335-F339 HydrophobicContact CD1-CE2 3.8Å; L335-F339 HydrophobicContact CG-CD2 4.49Å; L335-F339 HydrophobicContact CG-CE2 4.27Å; L335-F339 VanDerWaalsContact O-CD2 3.22Å; L335-F339 WeakPolarHBondContact O-CD2 3.37Å; L335-F339 PolarHBondContact O-N 3.5Å; V336-F339 PolarHBondContact O-N 3.28Å
340	S	93	Very high	90	Very high	41 Å²	41	52.9 Å²	52.9	29%	0.287	25%	0.254	S	S	.	.			trans	-114	106.2	-175.5	-179.2	0	0	0	0	112.4	V336 H342 F343 Y344	V336-S340 WeakPolarHBondContact O-CB 3.42Å; V336-S340 PolarHBondContact O-N 3.37Å; S340-H342 VanDerWaalsContact C-N 3.32Å; S340-H342 PolarHBondContact O-N 2.87Å; S340-F343 PolarHBondContact O-N 3.44Å; S340-F343 WeakPolarHBondContact OG-CB 3.34Å; S340-F343 PolarHBondContact OG-N 2.85Å; S340-Y344 PolarHBondContact O-N 2.97Å; S340-Y344 VanDerWaalsContact O-N 3.08Å
341	K	90.2	Very high	89.5	Confident	124 Å²	124	57.1 Å²	57.1	54%	0.539	27%	0.274	S	S	.	.	H	α-helix	trans	-57.6	-46	173.7	-170.9	176.2	179.1	-179.2	0	111.4	Y233 F343 Y344 Y345	Y233-K341 HydrophobicContact CD1-CB 3.99Å; Y233-K341 HydrophobicContact CD1-CD 4.41Å; Y233-K341 HydrophobicContact CD1-CG 3.9Å; Y233-K341 HydrophobicContact CD2-CB 3.91Å; Y233-K341 VanDerWaalsContact CD2-N 3.31Å; Y233-K341 HydrophobicContact CE1-CB 3.8Å; Y233-K341 HydrophobicContact CE1-CD 3.91Å; Y233-K341 HydrophobicContact CE1-CG 3.82Å; Y233-K341 HydrophobicContact CE2-CB 3.73Å; Y233-K341 HydrophobicContact CG-CB 4.02Å; Y233-K341 HydrophobicContact CG-CG 4.33Å; K341-F343 VanDerWaalsContact C-N 3.29Å; K341-F343 PolarHBondContact O-N 3.45Å; K341-Y344 PolarHBondContact O-N 3.5Å; K341-Y345 HydrophobicContact CD-CE2 4.47Å; K341-Y345 HydrophobicContact CG-CD2 3.7Å; K341-Y345 HydrophobicContact CG-CE2 3.73Å; K341-Y345 VanDerWaalsContact O-CD2 3.27Å; K341-Y345 WeakPolarHBondContact O-CD2 3.42Å; K341-Y345 PolarHBondContact O-N 2.88Å
342	H	90.7	Very high	89.3	Confident	142 Å²	142	60.7 Å²	60.7	66%	0.657	29%	0.292	S	S	*	.	H	α-helix	trans	-60.6	-41.4	-179	179.1	71.4	0	0	0	111.4	S340 Q346	S340-H342 VanDerWaalsContact C-N 3.32Å; S340-H342 PolarHBondContact O-N 2.87Å; H342-Q346 PolarHBondContact NE2-NE2 3.32Å; H342-Q346 VanDerWaalsContact NE2-NE2 3.13Å; H342-Q346 WeakPolarHBondContact O-CG 3.44Å; H342-Q346 PolarHBondContact O-N 3.14Å
343	F	90.7	Very high	89	Confident	53 Å²	53	57.5 Å²	57.5	23%	0.232	27%	0.272	C	S	.	.	H	α-helix	trans	-66.2	-44.3	178.6	-172.5	-99.4	0	0	0	112.6	Y333 V336 A337 S340 K341 Y345 Q346 F349	Y333-F343 HydrophobicContact CD1-CE1 4.38Å; Y333-F343 AromaticContact CD2-CE1 3.9Å; Y333-F343 HydrophobicContact CD2-CE1 3.9Å; Y333-F343 AromaticContact CD2-CZ 3.56Å; Y333-F343 HydrophobicContact CD2-CZ 3.56Å; Y333-F343 HydrophobicContact CE1-CE1 4.14Å; Y333-F343 AromaticContact CE2-CE1 3.64Å; Y333-F343 HydrophobicContact CE2-CE1 3.64Å; Y333-F343 HydrophobicContact CE2-CE2 4.27Å; Y333-F343 AromaticContact CE2-CZ 3.23Å; Y333-F343 HydrophobicContact CE2-CZ 3.23Å; Y333-F343 HydrophobicContact CG-CE1 4.24Å; Y333-F343 HydrophobicContact CG-CZ 4.34Å; Y333-F343 AromaticContact CZ-CE1 3.74Å; Y333-F343 AromaticContact CZ-CZ 3.78Å; V336-F343 HydrophobicContact CB-CD1 4.37Å; V336-F343 HydrophobicContact CB-CE1 4.19Å; V336-F343 HydrophobicContact CG1-CB 4.31Å; V336-F343 HydrophobicContact CG1-CD1 3.76Å; V336-F343 HydrophobicContact CG1-CD2 4.04Å; V336-F343 HydrophobicContact CG1-CE1 3.92Å; V336-F343 HydrophobicContact CG1-CE2 4.2Å; V336-F343 HydrophobicContact CG1-CG 3.79Å; V336-F343 HydrophobicContact CG1-CZ 4.11Å; A337-F343 HydrophobicContact CB-CD1 4.35Å; S340-F343 PolarHBondContact O-N 3.44Å; S340-F343 WeakPolarHBondContact OG-CB 3.34Å; S340-F343 PolarHBondContact OG-N 2.85Å; K341-F343 VanDerWaalsContact C-N 3.29Å; K341-F343 PolarHBondContact O-N 3.45Å; F343-Y345 PolarHBondContact O-N 3.18Å; F343-Q346 PolarHBondContact O-N 2.99Å; F343-F349 AromaticContact CD1-CD2 3.98Å; F343-F349 HydrophobicContact CD1-CD2 3.98Å; F343-F349 AromaticContact CD1-CE2 3.92Å; F343-F349 HydrophobicContact CD1-CE2 3.92Å; F343-F349 AromaticContact CE1-CD2 4Å; F343-F349 HydrophobicContact CE1-CD2 4Å; F343-F349 AromaticContact CE1-CE2 3.85Å; F343-F349 HydrophobicContact CE1-CE2 3.85Å
344	Y	87.4	Confident	88.7	Confident	4 Å²	4	57.4 Å²	57.4	2%	0.016	28%	0.275	C	S	.	.	H	α-helix	trans	-64.4	-37.4	-177.6	-176.1	-106.4	0	0	0	113.3	A337 S340 K341 F349 F350	A337-Y344 HydrophobicContact CB-CD2 4.25Å; S340-Y344 PolarHBondContact O-N 2.97Å; S340-Y344 VanDerWaalsContact O-N 3.08Å; K341-Y344 PolarHBondContact O-N 3.5Å; Y344-F349 HydrophobicContact CD2-CD1 4.07Å; Y344-F349 AromaticContact CD2-CE1 3.5Å; Y344-F349 HydrophobicContact CD2-CE1 3.5Å; Y344-F349 VanDerWaalsContact CD2-CE1 3.5Å; Y344-F349 HydrophobicContact CD2-CE2 4.06Å; Y344-F349 AromaticContact CD2-CZ 3.5Å; Y344-F349 HydrophobicContact CD2-CZ 3.5Å; Y344-F349 HydrophobicContact CE2-CD1 4.18Å; Y344-F349 AromaticContact CE2-CE1 3.46Å; Y344-F349 HydrophobicContact CE2-CE1 3.46Å; Y344-F349 VanDerWaalsContact CE2-CE1 3.46Å; Y344-F349 AromaticContact CE2-CZ 3.82Å; Y344-F349 HydrophobicContact CE2-CZ 3.82Å; Y344-F349 WeakPolarHBondContact O-CB 3Å; Y344-F349 WeakPolarHBondContact O-CG 3.32Å; Y344-F350 HydrophobicContact CE2-CE1 4.33Å
345	Y	86.1	Confident	88.6	Confident	133 Å²	133	63.7 Å²	63.7	52%	0.522	30%	0.298	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91.1	9	-178.5	-67.8	-68.5	0	0	0	114.3	K341 F343	K341-Y345 HydrophobicContact CD-CE2 4.47Å; K341-Y345 HydrophobicContact CG-CD2 3.7Å; K341-Y345 HydrophobicContact CG-CE2 3.73Å; K341-Y345 VanDerWaalsContact O-CD2 3.27Å; K341-Y345 WeakPolarHBondContact O-CD2 3.42Å; K341-Y345 PolarHBondContact O-N 2.88Å; F343-Y345 PolarHBondContact O-N 3.18Å
346	Q	87.9	Confident	88.5	Confident	89 Å²	89	63.1 Å²	63.1	42%	0.416	30%	0.295	S	S	.	.	S	Bend	trans	-65.6	144.3	172.5	-66.3	-154.2	-3.5	0	0	111.3	H342 F343 N348 F349	H342-Q346 PolarHBondContact NE2-NE2 3.32Å; H342-Q346 VanDerWaalsContact NE2-NE2 3.13Å; H342-Q346 WeakPolarHBondContact O-CG 3.44Å; H342-Q346 PolarHBondContact O-N 3.14Å; F343-Q346 PolarHBondContact O-N 2.99Å; Q346-N348 PolarHBondContact O-N 3.31Å; Q346-N348 VanDerWaalsContact O-N 3.12Å; Q346-F349 VanDerWaalsContact O-CB 3.27Å; Q346-F349 WeakPolarHBondContact O-CB 3.48Å; Q346-F349 PolarHBondContact O-N 3Å
347	H	82.3	Confident	88.4	Confident	110 Å²	110	60.3 Å²	60.3	51%	0.509	28%	0.278	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.2	-36.4	-177.3	178.8	-82.5	0	0	0	113.2
348	N	85	Confident	88.4	Confident	80 Å²	80	61 Å²	61	43%	0.428	28%	0.28	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.7	2	-174.9	-58.4	-11.4	0	0	0	113.2	Q346 F350 E351 I352	Q346-N348 PolarHBondContact O-N 3.31Å; Q346-N348 VanDerWaalsContact O-N 3.12Å; N348-F350 PolarHBondContact O-N 3.04Å; N348-E351 PolarHBondContact O-N 3.19Å; N348-I352 HydrophobicContact CB-CD1 4.23Å; N348-I352 WeakPolarHBondContact O-CG1 3.33Å; N348-I352 PolarHBondContact O-N 2.95Å
349	F	86	Confident	88.4	Confident	3 Å²	3	63.4 Å²	63.4	1%	0.013	29%	0.293	C	S	.	.	H	α-helix	trans	-59.5	-51.1	-172.2	174.6	-92.4	0	0	0	112.4	Y333 A337 F343 Y344 Q346 E351 I352 S353	Y333-F349 AromaticContact CD1-CE2 3.93Å; Y333-F349 HydrophobicContact CD1-CE2 3.93Å; Y333-F349 HydrophobicContact CD1-CZ 4.35Å; Y333-F349 AromaticContact CE1-CD2 3.5Å; Y333-F349 HydrophobicContact CE1-CD2 3.5Å; Y333-F349 VanDerWaalsContact CE1-CD2 3.5Å; Y333-F349 AromaticContact CE1-CE2 3.19Å; Y333-F349 HydrophobicContact CE1-CE2 3.19Å; Y333-F349 HydrophobicContact CE1-CG 4.28Å; Y333-F349 AromaticContact CE1-CZ 3.77Å; Y333-F349 HydrophobicContact CE1-CZ 3.77Å; Y333-F349 AromaticContact CZ-CD2 3.59Å; Y333-F349 AromaticContact CZ-CE2 3.74Å; Y333-F349 VanDerWaalsContact OH-CA 3.24Å; Y333-F349 WeakPolarHBondContact OH-CA 3.36Å; Y333-F349 WeakPolarHBondContact OH-CD2 3.15Å; Y333-F349 PolarHBondContact OH-O 2.81Å; A337-F349 HydrophobicContact CB-CE2 3.53Å; A337-F349 HydrophobicContact CB-CZ 3.6Å; F343-F349 AromaticContact CD1-CD2 3.98Å; F343-F349 HydrophobicContact CD1-CD2 3.98Å; F343-F349 AromaticContact CD1-CE2 3.92Å; F343-F349 HydrophobicContact CD1-CE2 3.92Å; F343-F349 AromaticContact CE1-CD2 4Å; F343-F349 HydrophobicContact CE1-CD2 4Å; F343-F349 AromaticContact CE1-CE2 3.85Å; F343-F349 HydrophobicContact CE1-CE2 3.85Å; Y344-F349 HydrophobicContact CD2-CD1 4.07Å; Y344-F349 AromaticContact CD2-CE1 3.5Å; Y344-F349 HydrophobicContact CD2-CE1 3.5Å; Y344-F349 VanDerWaalsContact CD2-CE1 3.5Å; Y344-F349 HydrophobicContact CD2-CE2 4.06Å; Y344-F349 AromaticContact CD2-CZ 3.5Å; Y344-F349 HydrophobicContact CD2-CZ 3.5Å; Y344-F349 HydrophobicContact CE2-CD1 4.18Å; Y344-F349 AromaticContact CE2-CE1 3.46Å; Y344-F349 HydrophobicContact CE2-CE1 3.46Å; Y344-F349 VanDerWaalsContact CE2-CE1 3.46Å; Y344-F349 AromaticContact CE2-CZ 3.82Å; Y344-F349 HydrophobicContact CE2-CZ 3.82Å; Y344-F349 WeakPolarHBondContact O-CB 3Å; Y344-F349 WeakPolarHBondContact O-CG 3.32Å; Q346-F349 VanDerWaalsContact O-CB 3.27Å; Q346-F349 WeakPolarHBondContact O-CB 3.48Å; Q346-F349 PolarHBondContact O-N 3Å; F349-E351 VanDerWaalsContact C-N 3.33Å; F349-E351 PolarHBondContact O-N 3.26Å; F349-I352 PolarHBondContact O-N 3.4Å; F349-S353 WeakPolarHBondContact O-CB 3.33Å; F349-S353 PolarHBondContact O-N 3.46Å
350	F	81.6	Confident	88.4	Confident	32 Å²	32	59 Å²	59	14%	0.14	27%	0.274	C	S	.	.	H	α-helix	trans	-68.6	-32.5	-178.2	-61.3	-60.4	0	0	0	112.8	P223 R225 A226 Y344 N348 T354	P223-F350 HydrophobicContact CB-CD1 3.57Å; P223-F350 HydrophobicContact CB-CE1 2.97Å; P223-F350 HydrophobicContact CB-CE2 4.26Å; P223-F350 HydrophobicContact CB-CG 4.44Å; P223-F350 HydrophobicContact CB-CZ 3.37Å; P223-F350 HydrophobicContact CG-CD1 4.09Å; P223-F350 HydrophobicContact CG-CE1 3.75Å; R225-F350 HydrophobicContact CB-CB 3.87Å; R225-F350 HydrophobicContact CB-CD2 4.34Å; R225-F350 HydrophobicContact CB-CG 4.19Å; A226-F350 HydrophobicContact CB-CD1 4.11Å; Y344-F350 HydrophobicContact CE2-CE1 4.33Å; N348-F350 PolarHBondContact O-N 3.04Å; F350-T354 WeakPolarHBondContact O-CB 3.43Å; F350-T354 PolarHBondContact O-N 3.44Å; F350-T354 PolarHBondContact O-OG1 2.87Å
351	E	84.1	Confident	88.5	Confident	93 Å²	93	57 Å²	57	44%	0.435	26%	0.26	S	S	.	.	H	α-helix	trans	-65.4	-49.7	175.8	-65.3	179.2	-162.1	0	0	110.5	N348 F349 T354 W355	N348-E351 PolarHBondContact O-N 3.19Å; F349-E351 VanDerWaalsContact C-N 3.33Å; F349-E351 PolarHBondContact O-N 3.26Å; E351-T354 WeakPolarHBondContact O-CB 3.42Å; E351-T354 PolarHBondContact O-N 3.39Å; E351-W355 PolarHBondContact O-N 3.08Å
352	I	88.1	Confident	88.7	Confident	74 Å²	74	54.2 Å²	54.2	38%	0.379	25%	0.251	S	S	.	.	H	α-helix	trans	-63.6	-46.3	177.3	-63.6	167.7	0	0	0	110.2	Y333 N348 F349 T354 W355 L356	Y333-I352 HydrophobicContact CD2-CG2 4.1Å; Y333-I352 HydrophobicContact CE1-CG2 4.45Å; Y333-I352 HydrophobicContact CE2-CB 4.15Å; Y333-I352 HydrophobicContact CE2-CG2 3.48Å; Y333-I352 VanDerWaalsContact CE2-CG2 3.48Å; N348-I352 HydrophobicContact CB-CD1 4.23Å; N348-I352 WeakPolarHBondContact O-CG1 3.33Å; N348-I352 PolarHBondContact O-N 2.95Å; F349-I352 PolarHBondContact O-N 3.4Å; I352-T354 PolarHBondContact O-N 3.24Å; I352-W355 PolarHBondContact O-N 3.08Å; I352-W355 VanDerWaalsContact O-N 3.09Å; I352-L356 HydrophobicContact CG2-CD1 4.07Å; I352-L356 HydrophobicContact CG2-CG 4.16Å; I352-L356 WeakPolarHBondContact O-CG 3.13Å; I352-L356 PolarHBondContact O-N 3.32Å
353	S	87.7	Confident	88.9	Confident	2 Å²	2	48 Å²	48	1%	0.014	22%	0.221	C	C	.	.	H	α-helix	trans	-56.5	-34.1	177	-174.8	0	0	0	0	112.7	F349 L357	F349-S353 WeakPolarHBondContact O-CB 3.33Å; F349-S353 PolarHBondContact O-N 3.46Å; S353-L357 WeakPolarHBondContact O-CB 3.41Å; S353-L357 PolarHBondContact O-N 3.34Å
354	T	86.3	Confident	89.1	Confident	25 Å²	25	45.4 Å²	45.4	15%	0.153	21%	0.21	C	C	.	.	H	α-helix	trans	-65.3	-49.3	175.8	-61.1	0	0	0	0	110.9	P227 F350 E351 I352 L356 L357 W358	P227-T354 WeakPolarHBondContact CD-OG1 3.41Å; P227-T354 HydrophobicContact CG-CG2 3.94Å; F350-T354 WeakPolarHBondContact O-CB 3.43Å; F350-T354 PolarHBondContact O-N 3.44Å; F350-T354 PolarHBondContact O-OG1 2.87Å; E351-T354 WeakPolarHBondContact O-CB 3.42Å; E351-T354 PolarHBondContact O-N 3.39Å; I352-T354 PolarHBondContact O-N 3.24Å; T354-L356 VanDerWaalsContact C-N 3.33Å; T354-L356 PolarHBondContact O-N 3.28Å; T354-L357 WeakPolarHBondContact O-CB 3.46Å; T354-L357 PolarHBondContact O-N 3.24Å; T354-W358 PolarHBondContact O-N 3.22Å
355	W	89.4	Confident	89.4	Confident	138 Å²	138	45.4 Å²	45.4	52%	0.523	21%	0.211	S	C	.	.	H	α-helix	trans	-62	-40	177.9	-70.5	116.8	0	0	0	112.9	L84 E351 I352 W358 L359	L84-W355 HydrophobicContact CD2-CH2 3.31Å; L84-W355 HydrophobicContact CD2-CZ2 3.96Å; L84-W355 HydrophobicContact CD2-CZ3 3.88Å; E351-W355 PolarHBondContact O-N 3.08Å; I352-W355 PolarHBondContact O-N 3.08Å; I352-W355 VanDerWaalsContact O-N 3.09Å; W355-W358 HydrophobicContact CZ3-CE3 4.41Å; W355-W358 HydrophobicContact CZ3-CZ3 4.46Å; W355-W358 WeakPolarHBondContact O-CB 3.39Å; W355-W358 PolarHBondContact O-N 2.71Å; W355-L359 PolarHBondContact O-N 3.46Å; W355-L359 VanDerWaalsContact O-N 3.08Å
356	L	92.2	Very high	89.9	Confident	28 Å²	28	41.6 Å²	41.6	15%	0.147	20%	0.199	C	C	.	.	H	α-helix	trans	-65.3	-40	176.7	-64	-174.3	0	0	0	111.9	P329 F330 Y333 I352 T354 L359 C360	P329-L356 HydrophobicContact CB-CD1 4.44Å; P329-L356 HydrophobicContact CB-CD2 3.54Å; F330-L356 HydrophobicContact CB-CB 4.19Å; F330-L356 HydrophobicContact CD2-CB 4.06Å; Y333-L356 HydrophobicContact CD1-CD1 3.94Å; Y333-L356 HydrophobicContact CD2-CD1 3.67Å; Y333-L356 HydrophobicContact CE2-CD1 4.43Å; Y333-L356 HydrophobicContact CG-CD1 3.39Å; I352-L356 HydrophobicContact CG2-CD1 4.07Å; I352-L356 HydrophobicContact CG2-CG 4.16Å; I352-L356 WeakPolarHBondContact O-CG 3.13Å; I352-L356 PolarHBondContact O-N 3.32Å; T354-L356 VanDerWaalsContact C-N 3.33Å; T354-L356 PolarHBondContact O-N 3.28Å; L356-L359 WeakPolarHBondContact O-CB 3.43Å; L356-L359 PolarHBondContact O-N 2.92Å; L356-C360 PolarHBondContact O-N 3Å; L356-C360 PolarHBondContact O-SG 3.27Å; L356-C360 VanDerWaalsContact O-SG 3.36Å
357	L	90	Very high	90.1	Very high	1 Å²	1	37.4 Å²	37.4	1%	0.005	18%	0.18	C	C	.	.	H	α-helix	trans	-63.2	-42.3	174.2	175.5	58.6	0	0	0	112.2	F161 P227 Q228 F330 S353 T354 L359 C360 Y361	F161-L357 HydrophobicContact CD2-CD1 4.43Å; F161-L357 HydrophobicContact CE2-CD1 3.47Å; F161-L357 VanDerWaalsContact CE2-CD1 3.47Å; F161-L357 HydrophobicContact CZ-CD1 3.7Å; P227-L357 HydrophobicContact CB-CD2 4.24Å; P227-L357 HydrophobicContact CG-CD2 3.54Å; Q228-L357 HydrophobicContact CB-CD2 4.11Å; Q228-L357 HydrophobicContact CG-CD2 3.48Å; Q228-L357 VanDerWaalsContact CG-CD2 3.48Å; F330-L357 HydrophobicContact CE2-CB 4.34Å; S353-L357 WeakPolarHBondContact O-CB 3.41Å; S353-L357 PolarHBondContact O-N 3.34Å; T354-L357 WeakPolarHBondContact O-CB 3.46Å; T354-L357 PolarHBondContact O-N 3.24Å; L357-L359 PolarHBondContact O-N 2.99Å; L357-C360 HydrophobicContact CD1-CB 4.48Å; L357-C360 WeakPolarHBondContact O-CA 3.37Å; L357-C360 VanDerWaalsContact O-CB 3.28Å; L357-C360 WeakPolarHBondContact O-CB 3.26Å; L357-C360 PolarHBondContact O-N 3.24Å; L357-Y361 HydrophobicContact CD1-CD1 4.39Å; L357-Y361 HydrophobicContact CD1-CD2 4.47Å; L357-Y361 HydrophobicContact CD1-CE1 3.86Å; L357-Y361 HydrophobicContact CD1-CE2 3.96Å; L357-Y361 HydrophobicContact CD2-CE2 3.74Å; L357-Y361 HydrophobicContact CG-CD2 4.09Å; L357-Y361 HydrophobicContact CG-CE1 4.4Å; L357-Y361 HydrophobicContact CG-CE2 3.57Å; L357-Y361 PolarHBondContact O-N 2.79Å
358	W	91.4	Very high	90.5	Very high	13 Å²	13	32.6 Å²	32.6	5%	0.049	16%	0.158	C	C	.	.	H	α-helix	trans	-59.9	-36.6	176.4	-82	45.9	0	0	0	112.3	L84 I87 M88 I91 I142 T354 W355 C360 Y361 L362	L84-W358 HydrophobicContact CB-CH2 3.58Å; L84-W358 HydrophobicContact CB-CZ2 3.97Å; L84-W358 HydrophobicContact CD2-CH2 3.44Å; L84-W358 VanDerWaalsContact CD2-CH2 3.44Å; L84-W358 HydrophobicContact CD2-CZ2 4.04Å; L84-W358 HydrophobicContact CD2-CZ3 4Å; L84-W358 HydrophobicContact CG-CH2 4.07Å; L84-W358 HydrophobicContact CG-CZ2 4.48Å; L84-W358 WeakPolarHBondContact O-CH2 3.1Å; I87-W358 HydrophobicContact CB-CH2 4.29Å; I87-W358 HydrophobicContact CB-CZ3 3.75Å; I87-W358 HydrophobicContact CG2-CE3 4.14Å; I87-W358 HydrophobicContact CG2-CH2 4.47Å; I87-W358 HydrophobicContact CG2-CZ3 3.5Å; M88-W358 HydrophobicContact CB-CH2 4.47Å; M88-W358 HydrophobicContact CB-CZ2 4.45Å; M88-W358 HydrophobicContact CG-CD2 3.91Å; M88-W358 HydrophobicContact CG-CE3 4.11Å; M88-W358 HydrophobicContact CG-CH2 3.41Å; M88-W358 VanDerWaalsContact CG-CH2 3.41Å; M88-W358 HydrophobicContact CG-CZ2 3.14Å; M88-W358 HydrophobicContact CG-CZ3 3.88Å; M88-W358 HydrophobicContact SD-CD2 3.43Å; M88-W358 HydrophobicContact SD-CE3 3.85Å; M88-W358 HydrophobicContact SD-CG 3.9Å; M88-W358 HydrophobicContact SD-CH2 4.23Å; M88-W358 HydrophobicContact SD-CZ2 3.84Å; M88-W358 HydrophobicContact SD-CZ3 4.23Å; I91-W358 HydrophobicContact CD1-CE3 4.4Å; I142-W358 HydrophobicContact CD1-CZ2 3.57Å; T354-W358 PolarHBondContact O-N 3.22Å; W355-W358 HydrophobicContact CZ3-CE3 4.41Å; W355-W358 HydrophobicContact CZ3-CZ3 4.46Å; W355-W358 WeakPolarHBondContact O-CB 3.39Å; W355-W358 PolarHBondContact O-N 2.71Å; W358-C360 VanDerWaalsContact C-N 3.29Å; W358-C360 PolarHBondContact O-N 2.84Å; W358-Y361 PolarHBondContact O-N 2.99Å; W358-Y361 VanDerWaalsContact O-N 3.16Å; W358-L362 WeakPolarHBondContact O-CB 3.45Å; W358-L362 PolarHBondContact O-N 3.23Å
359	L	93.3	Very high	90.8	Very high	51 Å²	51	33.1 Å²	33.1	27%	0.267	16%	0.161	S	C	.	.	H	α-helix	trans	-63.4	-37.2	174	-163.5	68.2	0	0	0	111.6	V325 C326 P329 W355 L356 L357 L362 K363	V325-L359 WeakPolarHBondContact O-CD2 3.23Å; C326-L359 HydrophobicContact CB-CG 4.35Å; C326-L359 WeakPolarHBondContact CB-O 3.17Å; C326-L359 PolarHBondContact SG-O 3.49Å; P329-L359 HydrophobicContact CG-CD2 4.32Å; W355-L359 PolarHBondContact O-N 3.46Å; W355-L359 VanDerWaalsContact O-N 3.08Å; L356-L359 WeakPolarHBondContact O-CB 3.43Å; L356-L359 PolarHBondContact O-N 2.92Å; L357-L359 PolarHBondContact O-N 2.99Å; L359-L362 HydrophobicContact CD1-CD2 4.34Å; L359-L362 PolarHBondContact O-N 2.94Å; L359-K363 PolarHBondContact O-N 3.41Å
360	C	93.2	Very high	91	Very high	2 Å²	2	33.9 Å²	33.9	1%	0.014	17%	0.165	C	C	.	.	H	α-helix	trans	-64.3	-40.1	171.1	-56.6	0	0	0	0	112.4	C326 W327 F330 L356 L357 W358 K363	C326-C360 PolarHBondContact O-SG 3.13Å; W327-C360 HydrophobicContact CH2-CB 4.06Å; W327-C360 HydrophobicContact CZ2-CB 3.89Å; F330-C360 WeakPolarHBondContact CB-SG 3.34Å; L356-C360 PolarHBondContact O-N 3Å; L356-C360 PolarHBondContact O-SG 3.27Å; L356-C360 VanDerWaalsContact O-SG 3.36Å; L357-C360 HydrophobicContact CD1-CB 4.48Å; L357-C360 WeakPolarHBondContact O-CA 3.37Å; L357-C360 VanDerWaalsContact O-CB 3.28Å; L357-C360 WeakPolarHBondContact O-CB 3.26Å; L357-C360 PolarHBondContact O-N 3.24Å; W358-C360 VanDerWaalsContact C-N 3.29Å; W358-C360 PolarHBondContact O-N 2.84Å; C360-K363 WeakPolarHBondContact O-CB 3.45Å; C360-K363 PolarHBondContact O-N 2.97Å
361	Y	94.6	Very high	91.3	Very high	1 Å²	1	32.5 Å²	32.5	0%	0.004	16%	0.158	C	C	.	.	H	α-helix	trans	-67.7	-37	175.1	-65.6	-30.5	0	0	0	112.6	M88 L130 M135 A138 F161 Q228 L357 W358 K363 S364	M88-Y361 HydrophobicContact CE-CD2 3.66Å; M88-Y361 HydrophobicContact CE-CE2 3.95Å; M88-Y361 HydrophobicContact SD-CD2 4.27Å; L130-Y361 HydrophobicContact CD1-CE1 4.3Å; L130-Y361 HydrophobicContact CD2-CD1 4.37Å; L130-Y361 HydrophobicContact CG-CE1 4.47Å; M135-Y361 HydrophobicContact CE-CD1 3.91Å; M135-Y361 HydrophobicContact CE-CG 4.06Å; M135-Y361 HydrophobicContact CG-CD1 4.06Å; M135-Y361 HydrophobicContact CG-CD2 4.35Å; M135-Y361 HydrophobicContact CG-CE1 4.24Å; M135-Y361 HydrophobicContact CG-CE2 4.5Å; M135-Y361 HydrophobicContact CG-CG 4.11Å; A138-Y361 HydrophobicContact CB-CE2 3.92Å; F161-Y361 HydrophobicContact CD2-CE1 4.29Å; F161-Y361 AromaticContact CE2-CE1 3.98Å; F161-Y361 HydrophobicContact CE2-CE1 3.98Å; Q228-Y361 PolarHBondContact OE1-OH 3.46Å; L357-Y361 HydrophobicContact CD1-CD1 4.39Å; L357-Y361 HydrophobicContact CD1-CD2 4.47Å; L357-Y361 HydrophobicContact CD1-CE1 3.86Å; L357-Y361 HydrophobicContact CD1-CE2 3.96Å; L357-Y361 HydrophobicContact CD2-CE2 3.74Å; L357-Y361 HydrophobicContact CG-CD2 4.09Å; L357-Y361 HydrophobicContact CG-CE1 4.4Å; L357-Y361 HydrophobicContact CG-CE2 3.57Å; L357-Y361 PolarHBondContact O-N 2.79Å; W358-Y361 PolarHBondContact O-N 2.99Å; W358-Y361 VanDerWaalsContact O-N 3.16Å; Y361-K363 VanDerWaalsContact C-N 3.28Å; Y361-K363 PolarHBondContact O-N 3.35Å; Y361-S364 VanDerWaalsContact O-CB 3.24Å; Y361-S364 WeakPolarHBondContact O-CB 3.34Å; Y361-S364 PolarHBondContact O-N 2.95Å
362	L	94.8	Very high	91.5	Very high	65 Å²	65	32.3 Å²	32.3	34%	0.34	16%	0.155	S	C	.	.	H	α-helix	trans	-60.3	-37.2	177.4	-177.2	61.8	0	0	0	111.9	I91 W358 L359 S364 A365 L366	I91-L362 HydrophobicContact CD1-CD1 4.4Å; I91-L362 HydrophobicContact CG1-CD1 4.34Å; W358-L362 WeakPolarHBondContact O-CB 3.45Å; W358-L362 PolarHBondContact O-N 3.23Å; L359-L362 HydrophobicContact CD1-CD2 4.34Å; L359-L362 PolarHBondContact O-N 2.94Å; L362-S364 PolarHBondContact O-N 3Å; L362-A365 PolarHBondContact O-N 3.43Å; L362-A365 VanDerWaalsContact O-N 3.09Å; L362-L366 HydrophobicContact CD1-CG 4.36Å; L362-L366 HydrophobicContact CD2-CD1 4.47Å; L362-L366 HydrophobicContact CG-CD1 4Å; L362-L366 HydrophobicContact CG-CG 4.15Å; L362-L366 WeakPolarHBondContact O-CG 3.38Å; L362-L366 PolarHBondContact O-N 3.33Å
363	K	94.1	Very high	91.3	Very high	10 Å²	10	39.3 Å²	39.3	4%	0.043	18%	0.176	C	C	.	.	H	α-helix	trans	-48.2	-47.8	172.2	173	-159.5	152	-72.5	0	111.5	D127 V322 C326 L359 C360 Y361 A365 L366 N367	D127-K363 IonicContact OD1-NZ 3.44Å; D127-K363 PolarHBondContact OD1-NZ 2.9Å; D127-K363 IonicContact OD2-NZ 3.05Å; D127-K363 PolarHBondContact OD2-NZ 3.44Å; V322-K363 HydrophobicContact CG1-CG 4.36Å; C326-K363 HydrophobicContact CB-CB 3.85Å; L359-K363 PolarHBondContact O-N 3.41Å; C360-K363 WeakPolarHBondContact O-CB 3.45Å; C360-K363 PolarHBondContact O-N 2.97Å; Y361-K363 VanDerWaalsContact C-N 3.28Å; Y361-K363 PolarHBondContact O-N 3.35Å; K363-A365 VanDerWaalsContact C-N 3.27Å; K363-A365 PolarHBondContact O-N 3.43Å; K363-L366 PolarHBondContact O-N 3.45Å; K363-L366 VanDerWaalsContact O-N 3.12Å; K363-N367 PolarHBondContact NZ-ND2 2.91Å; K363-N367 PolarHBondContact O-N 3.16Å; K363-N367 VanDerWaalsContact O-N 3.15Å
364	S	94.9	Very high	91.1	Very high	0 Å²	0	42.2 Å²	42.2	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-60.9	-37.6	-176	-169.4	0	0	0	0	111.9	S95 N99 D127 Y361 L362 P368	S95-S364 WeakPolarHBondContact OG-CB 3.07Å; S95-S364 PolarHBondContact OG-OG 3.24Å; N99-S364 PolarHBondContact ND2-O 2.7Å; D127-S364 WeakPolarHBondContact CB-OG 3.3Å; D127-S364 PolarHBondContact O-OG 3.34Å; Y361-S364 VanDerWaalsContact O-CB 3.24Å; Y361-S364 WeakPolarHBondContact O-CB 3.34Å; Y361-S364 PolarHBondContact O-N 2.95Å; L362-S364 PolarHBondContact O-N 3Å; S364-P368 WeakPolarHBondContact O-CD 3.46Å
365	A	95.3	Very high	90.8	Very high	4 Å²	4	43.2 Å²	43.2	3%	0.033	19%	0.191	C	C	.	.	H	α-helix	trans	-74.8	-32.4	174.5	0	0	0	0	0	113.3	I91 V94 L362 K363	I91-A365 HydrophobicContact CG2-CB 4.25Å; V94-A365 HydrophobicContact CB-CB 4.17Å; V94-A365 HydrophobicContact CG1-CB 3.89Å; L362-A365 PolarHBondContact O-N 3.43Å; L362-A365 VanDerWaalsContact O-N 3.09Å; K363-A365 VanDerWaalsContact C-N 3.27Å; K363-A365 PolarHBondContact O-N 3.43Å
366	L	94.9	Very high	90.2	Very high	52 Å²	52	44 Å²	44	27%	0.272	20%	0.198	S	C	.	.	H	α-helix	trans	-70.8	-31.2	-179.9	-69.8	173.9	0	0	0	113	V322 L362 K363 L369 I370	V322-L366 HydrophobicContact CG1-CB 4.31Å; V322-L366 HydrophobicContact CG1-CD1 3.82Å; L362-L366 HydrophobicContact CD1-CG 4.36Å; L362-L366 HydrophobicContact CD2-CD1 4.47Å; L362-L366 HydrophobicContact CG-CD1 4Å; L362-L366 HydrophobicContact CG-CG 4.15Å; L362-L366 WeakPolarHBondContact O-CG 3.38Å; L362-L366 PolarHBondContact O-N 3.33Å; K363-L366 PolarHBondContact O-N 3.45Å; K363-L366 VanDerWaalsContact O-N 3.12Å; L366-L369 HydrophobicContact CD2-CD1 4.48Å; L366-L369 WeakPolarHBondContact O-CB 3.34Å; L366-L369 PolarHBondContact O-N 3.22Å; L366-I370 HydrophobicContact CB-CD1 4.2Å; L366-I370 WeakPolarHBondContact O-CD1 3.27Å; L366-I370 VanDerWaalsContact O-CG1 3.22Å; L366-I370 WeakPolarHBondContact O-CG1 3.27Å; L366-I370 PolarHBondContact O-N 3.09Å
367	N	92.1	Very high	89.4	Confident	2 Å²	2	50 Å²	50	1%	0.011	22%	0.223	C	C	.	.	H	α-helix	trans	-54.2	-56.9	-176.8	-82.7	-11.6	0	0	0	113.2	D127 K363 L369 I370 Y371	D127-N367 PolarHBondContact OD2-ND2 2.86Å; K363-N367 PolarHBondContact NZ-ND2 2.91Å; K363-N367 PolarHBondContact O-N 3.16Å; K363-N367 VanDerWaalsContact O-N 3.15Å; N367-L369 VanDerWaalsContact C-N 3.31Å; N367-L369 PolarHBondContact O-N 2.99Å; N367-I370 PolarHBondContact O-N 2.88Å; N367-Y371 HydrophobicContact CB-CE2 4.15Å; N367-Y371 VanDerWaalsContact O-CD2 3.23Å; N367-Y371 WeakPolarHBondContact O-CD2 3.35Å; N367-Y371 VanDerWaalsContact O-CG 3.28Å; N367-Y371 PolarHBondContact O-N 3.41Å
368	P	91.4	Very high	88.8	Confident	8 Å²	8	50.6 Å²	50.6	5%	0.052	23%	0.226	C	C	.	.	H	α-helix	trans	-57.8	-38.1	174.9	-26.5	34.2	0	0	0	114.4	N99 V102 S364 I370 Y371 Y372	N99-P368 HydrophobicContact CB-CG 4.32Å; N99-P368 VanDerWaalsContact CG-CG 3.5Å; N99-P368 VanDerWaalsContact OD1-CG 3.28Å; N99-P368 WeakPolarHBondContact OD1-CG 3.49Å; V102-P368 HydrophobicContact CG2-CB 4.25Å; V102-P368 HydrophobicContact CG2-CG 4.34Å; S364-P368 WeakPolarHBondContact O-CD 3.46Å; P368-I370 VanDerWaalsContact C-N 3.35Å; P368-Y371 PolarHBondContact O-N 3.18Å; P368-Y372 WeakPolarHBondContact O-CB 3.41Å; P368-Y372 PolarHBondContact O-N 3.04Å
369	L	91.4	Very high	88.4	Confident	92 Å²	92	52.8 Å²	52.8	48%	0.482	24%	0.236	S	C	.	.	H	α-helix	trans	-65.2	-40.6	179.1	-63.7	176	0	0	0	111.3	V94 L366 N367 Y372 W373	V94-L369 HydrophobicContact CG1-CD1 4.33Å; V94-L369 HydrophobicContact CG1-CG 4.45Å; L366-L369 HydrophobicContact CD2-CD1 4.48Å; L366-L369 WeakPolarHBondContact O-CB 3.34Å; L366-L369 PolarHBondContact O-N 3.22Å; N367-L369 VanDerWaalsContact C-N 3.31Å; N367-L369 PolarHBondContact O-N 2.99Å; L369-Y372 PolarHBondContact O-N 3.37Å; L369-W373 PolarHBondContact O-N 3.49Å
370	I	90.8	Very high	87.8	Confident	19 Å²	19	53.5 Å²	53.5	10%	0.097	24%	0.24	C	C	.	.	H	α-helix	trans	-63.4	-44.8	174.7	-65.7	159.8	0	0	0	109.8	T315 I318 L319 V322 L366 N367 P368 W373 R374	T315-I370 HydrophobicContact CG2-CG2 4.05Å; I318-I370 HydrophobicContact CG2-CD1 4.04Å; I318-I370 HydrophobicContact CG2-CG1 4.17Å; I318-I370 HydrophobicContact CG2-CG2 4.17Å; L319-I370 HydrophobicContact CD2-CB 4.2Å; L319-I370 HydrophobicContact CD2-CD1 3.87Å; L319-I370 HydrophobicContact CD2-CG2 3.83Å; L319-I370 HydrophobicContact CG-CG2 4.21Å; V322-I370 HydrophobicContact CG2-CD1 3.98Å; L366-I370 HydrophobicContact CB-CD1 4.2Å; L366-I370 WeakPolarHBondContact O-CD1 3.27Å; L366-I370 VanDerWaalsContact O-CG1 3.22Å; L366-I370 WeakPolarHBondContact O-CG1 3.27Å; L366-I370 PolarHBondContact O-N 3.09Å; N367-I370 PolarHBondContact O-N 2.88Å; P368-I370 VanDerWaalsContact C-N 3.35Å; I370-W373 PolarHBondContact O-N 3.02Å; I370-R374 HydrophobicContact CG2-CG 4.12Å; I370-R374 WeakPolarHBondContact O-CB 3.39Å; I370-R374 WeakPolarHBondContact O-CG 3.16Å; I370-R374 PolarHBondContact O-N 3.44Å
371	Y	87.5	Confident	87.1	Confident	2 Å²	2	54 Å²	54	1%	0.008	24%	0.244	C	C	.	.	H	α-helix	trans	-62.8	-44.6	177.7	-55.4	-33.2	0	0	0	112	V102 L120 L123 L319 N367 P368 R374 I375	V102-Y371 HydrophobicContact CG2-CD2 3.87Å; V102-Y371 HydrophobicContact CG2-CE2 4.39Å; L120-Y371 HydrophobicContact CD2-CE1 3.79Å; L123-Y371 VanDerWaalsContact CD2-OH 3.26Å; L123-Y371 WeakPolarHBondContact CD2-OH 3.33Å; L319-Y371 HydrophobicContact CD1-CE1 3.77Å; L319-Y371 HydrophobicContact CD2-CE1 3.76Å; L319-Y371 HydrophobicContact CG-CE1 4.37Å; N367-Y371 HydrophobicContact CB-CE2 4.15Å; N367-Y371 VanDerWaalsContact O-CD2 3.23Å; N367-Y371 WeakPolarHBondContact O-CD2 3.35Å; N367-Y371 VanDerWaalsContact O-CG 3.28Å; N367-Y371 PolarHBondContact O-N 3.41Å; P368-Y371 PolarHBondContact O-N 3.18Å; Y371-R374 PolarHBondContact O-N 3.21Å; Y371-I375 HydrophobicContact CD1-CD1 4.08Å; Y371-I375 HydrophobicContact CG-CD1 4.47Å; Y371-I375 VanDerWaalsContact O-CB 3.31Å; Y371-I375 WeakPolarHBondContact O-CB 3.3Å; Y371-I375 PolarHBondContact O-N 3.12Å
372	Y	87.3	Confident	86.4	Confident	90 Å²	90	55.1 Å²	55.1	35%	0.353	25%	0.252	S	S	.	.	H	α-helix	trans	-58.3	-49.4	177.9	179	-99.4	0	0	0	112.3	P368 L369 H379 C382	P368-Y372 WeakPolarHBondContact O-CB 3.41Å; P368-Y372 PolarHBondContact O-N 3.04Å; L369-Y372 PolarHBondContact O-N 3.37Å; Y372-H379 AromaticContact CE1-CD2 3.92Å; Y372-H379 HydrophobicContact CE2-CB 4.49Å; Y372-H379 AromaticContact CE2-CD2 3.48Å; Y372-H379 VanDerWaalsContact CE2-CD2 3.48Å; Y372-H379 WeakPolarHBondContact CE2-CD2 3.47Å; Y372-H379 AromaticContact CZ-CD2 3.35Å; Y372-H379 AromaticContact CZ-NE2 3.87Å; Y372-H379 PolarHBondContact OH-CD2 2.73Å; Y372-H379 PolarHBondContact OH-NE2 2.94Å; Y372-C382 HydrophobicContact CD2-CB 4.18Å; Y372-C382 HydrophobicContact CE2-CB 4.23Å
373	W	85.6	Confident	85.7	Confident	221 Å²	221	55.1 Å²	55.1	84%	0.837	25%	0.252	S	S	*	.	H	α-helix	trans	-72.1	-39.3	-178.8	-166.9	-8.5	0	0	0	111.9	L369 I370	L369-W373 PolarHBondContact O-N 3.49Å; I370-W373 PolarHBondContact O-N 3.02Å
374	R	82.6	Confident	85	Confident	63 Å²	63	59.7 Å²	59.7	24%	0.238	28%	0.277	C	S	.	.	H	α-helix	trans	-93.5	-26.1	-166.1	-58.6	-59.4	-53.9	-67.3	-16.3	114.2	R311 T314 T315 I370 Y371	R311-R374 PolarHBondContact O-NH2 2.96Å; T314-R374 VanDerWaalsContact C-NH2 3.27Å; T314-R374 PolarHBondContact O-NH1 3.23Å; T315-R374 HydrophobicContact CG2-CB 3.67Å; T315-R374 HydrophobicContact CG2-CG 4.22Å; T315-R374 VanDerWaalsContact N-NH2 3.19Å; T315-R374 WeakPolarHBondContact OG1-CB 3.24Å; T315-R374 PolarHBondContact OG1-NH2 3.13Å; I370-R374 HydrophobicContact CG2-CG 4.12Å; I370-R374 WeakPolarHBondContact O-CB 3.39Å; I370-R374 WeakPolarHBondContact O-CG 3.16Å; I370-R374 PolarHBondContact O-N 3.44Å; Y371-R374 PolarHBondContact O-N 3.21Å
375	I	79.8	Confident	84	Confident	45 Å²	45	62.6 Å²	62.6	23%	0.231	29%	0.291	C	S	.	.			trans	-108.2	100.3	-176	-53.2	175.3	0	0	0	108.8	L120 T315 Y371 K377 F378 H379	L120-I375 HydrophobicContact CD1-CD1 4.4Å; T315-I375 HydrophobicContact CG2-CG1 4.47Å; Y371-I375 HydrophobicContact CD1-CD1 4.08Å; Y371-I375 HydrophobicContact CG-CD1 4.47Å; Y371-I375 VanDerWaalsContact O-CB 3.31Å; Y371-I375 WeakPolarHBondContact O-CB 3.3Å; Y371-I375 PolarHBondContact O-N 3.12Å; I375-K377 VanDerWaalsContact C-N 3.29Å; I375-K377 HydrophobicContact CG2-CB 4.44Å; I375-K377 PolarHBondContact O-N 3.49Å; I375-F378 HydrophobicContact CB-CB 3.67Å; I375-F378 HydrophobicContact CG2-CB 3.73Å; I375-F378 WeakPolarHBondContact O-CA 3.35Å; I375-F378 WeakPolarHBondContact O-CB 3.47Å; I375-F378 PolarHBondContact O-N 3.5Å; I375-H379 PolarHBondContact O-N 3.04Å
376	K	77.2	Confident	83.1	Confident	156 Å²	156	66 Å²	66	68%	0.678	31%	0.308	S	S	*	.	H	α-helix	trans	-54.6	-42.2	-179.1	-173.4	175.3	-179.8	178	0	113.4	F378 H379 D380	K376-F378 PolarHBondContact O-N 3.32Å; K376-H379 WeakPolarHBondContact O-CB 3.43Å; K376-H379 PolarHBondContact O-N 2.86Å; K376-D380 PolarHBondContact O-N 3.27Å
377	K	75.5	Confident	82	Confident	154 Å²	154	67.1 Å²	67.1	67%	0.67	32%	0.318	S	S	*	.	H	α-helix	trans	-60.7	-32	175.5	-67.8	-174.3	178.4	-177.6	0	112.7	M112 I375 A381	M112-K377 HydrophobicContact SD-CB 4.26Å; I375-K377 VanDerWaalsContact C-N 3.29Å; I375-K377 HydrophobicContact CG2-CB 4.44Å; I375-K377 PolarHBondContact O-N 3.49Å; K377-A381 VanDerWaalsContact O-CB 3.31Å; K377-A381 WeakPolarHBondContact O-CB 3.31Å; K377-A381 PolarHBondContact O-N 2.83Å; K377-A381 VanDerWaalsContact O-N 3.15Å
378	F	77.4	Confident	80.3	Confident	13 Å²	13	76.1 Å²	76.1	6%	0.057	36%	0.357	C	S	.	.	H	α-helix	trans	-74.3	-48.3	177.5	-168.7	-80.6	0	0	0	110.2	V102 M105 I375 K376 D380 A381 C382	V102-F378 HydrophobicContact CB-CE2 4.09Å; V102-F378 HydrophobicContact CB-CZ 4.06Å; V102-F378 HydrophobicContact CG1-CE2 4.09Å; V102-F378 HydrophobicContact CG2-CE1 4.45Å; V102-F378 HydrophobicContact CG2-CE2 3.73Å; V102-F378 HydrophobicContact CG2-CZ 3.36Å; M105-F378 HydrophobicContact CE-CB 4.17Å; M105-F378 HydrophobicContact CE-CD1 3.84Å; M105-F378 HydrophobicContact CE-CD2 3.49Å; M105-F378 VanDerWaalsContact CE-CD2 3.49Å; M105-F378 HydrophobicContact CE-CE1 3.98Å; M105-F378 HydrophobicContact CE-CE2 3.63Å; M105-F378 HydrophobicContact CE-CG 3.58Å; M105-F378 HydrophobicContact CE-CZ 3.85Å; M105-F378 WeakPolarHBondContact CE-O 3.38Å; M105-F378 HydrophobicContact SD-CD1 4.24Å; M105-F378 HydrophobicContact SD-CD2 4.04Å; M105-F378 HydrophobicContact SD-CE1 3.76Å; M105-F378 HydrophobicContact SD-CE2 3.5Å; M105-F378 VanDerWaalsContact SD-CE2 3.5Å; M105-F378 HydrophobicContact SD-CG 4.36Å; M105-F378 HydrophobicContact SD-CZ 3.32Å; M105-F378 WeakPolarHBondContact SD-CZ 3.07Å; I375-F378 HydrophobicContact CB-CB 3.67Å; I375-F378 HydrophobicContact CG2-CB 3.73Å; I375-F378 WeakPolarHBondContact O-CA 3.35Å; I375-F378 WeakPolarHBondContact O-CB 3.47Å; I375-F378 PolarHBondContact O-N 3.5Å; K376-F378 PolarHBondContact O-N 3.32Å; F378-D380 VanDerWaalsContact C-N 3.33Å; F378-D380 PolarHBondContact O-N 3.23Å; F378-A381 PolarHBondContact O-N 3.49Å; F378-C382 WeakPolarHBondContact O-CB 3.2Å; F378-C382 PolarHBondContact O-N 3.41Å
379	H	82.6	Confident	78.8	Confident	58 Å²	58	80.1 Å²	80.1	27%	0.269	39%	0.385	S	S	.	.	H	α-helix	trans	-50.5	-52.2	172	173.3	-89.7	0	0	0	112.2	Y372 I375 K376 A381 C382 L383	Y372-H379 AromaticContact CE1-CD2 3.92Å; Y372-H379 HydrophobicContact CE2-CB 4.49Å; Y372-H379 AromaticContact CE2-CD2 3.48Å; Y372-H379 VanDerWaalsContact CE2-CD2 3.48Å; Y372-H379 WeakPolarHBondContact CE2-CD2 3.47Å; Y372-H379 AromaticContact CZ-CD2 3.35Å; Y372-H379 AromaticContact CZ-NE2 3.87Å; Y372-H379 PolarHBondContact OH-CD2 2.73Å; Y372-H379 PolarHBondContact OH-NE2 2.94Å; I375-H379 PolarHBondContact O-N 3.04Å; K376-H379 WeakPolarHBondContact O-CB 3.43Å; K376-H379 PolarHBondContact O-N 2.86Å; H379-A381 PolarHBondContact O-N 2.88Å; H379-C382 WeakPolarHBondContact O-CB 3.45Å; H379-C382 PolarHBondContact O-N 3.02Å; H379-C382 VanDerWaalsContact O-N 3.16Å; H379-L383 WeakPolarHBondContact CE1-CD1 3.22Å; H379-L383 PolarHBondContact O-N 2.84Å
380	D	81.9	Confident	77.1	Confident	67 Å²	67	83.2 Å²	83.2	36%	0.358	40%	0.395	S	S	.	.	H	α-helix	trans	-64.2	-42.6	-177.1	-61.8	-17	0	0	0	111.4	K376 F378 C382 L383 D384	K376-D380 PolarHBondContact O-N 3.27Å; F378-D380 VanDerWaalsContact C-N 3.33Å; F378-D380 PolarHBondContact O-N 3.23Å; D380-C382 VanDerWaalsContact C-N 3.32Å; D380-C382 PolarHBondContact O-N 3.35Å; D380-L383 PolarHBondContact O-N 3.4Å; D380-D384 PolarHBondContact O-N 2.92Å
381	A	77.3	Confident	75.4	Confident	11 Å²	11	87.7 Å²	87.7	9%	0.091	41%	0.413	C	S	.	.	H	α-helix	trans	-68.8	-28	176.4	0	0	0	0	0	113.2	M105 K377 F378 H379 M385	M105-A381 HydrophobicContact CE-CB 3.42Å; M105-A381 VanDerWaalsContact CE-CB 3.42Å; K377-A381 VanDerWaalsContact O-CB 3.31Å; K377-A381 WeakPolarHBondContact O-CB 3.31Å; K377-A381 PolarHBondContact O-N 2.83Å; K377-A381 VanDerWaalsContact O-N 3.15Å; F378-A381 PolarHBondContact O-N 3.49Å; H379-A381 PolarHBondContact O-N 2.88Å; A381-M385 WeakPolarHBondContact O-CG 3.31Å; A381-M385 PolarHBondContact O-N 2.97Å
382	C	79.2	Confident	73.6	Confident	25 Å²	25	96.7 Å²	96.7	17%	0.169	45%	0.453	C	S	.	.	H	α-helix	trans	-67.7	-45.9	172.2	-172.6	0	0	0	0	110.6	M105 Y372 F378 H379 D380 D384 M385 M386	M105-C382 HydrophobicContact CE-CB 4.43Å; M105-C382 HydrophobicContact SD-CB 4.4Å; Y372-C382 HydrophobicContact CD2-CB 4.18Å; Y372-C382 HydrophobicContact CE2-CB 4.23Å; F378-C382 WeakPolarHBondContact O-CB 3.2Å; F378-C382 PolarHBondContact O-N 3.41Å; H379-C382 WeakPolarHBondContact O-CB 3.45Å; H379-C382 PolarHBondContact O-N 3.02Å; H379-C382 VanDerWaalsContact O-N 3.16Å; D380-C382 VanDerWaalsContact C-N 3.32Å; D380-C382 PolarHBondContact O-N 3.35Å; C382-D384 VanDerWaalsContact C-N 3.26Å; C382-D384 PolarHBondContact O-N 3.12Å; C382-M385 PolarHBondContact O-N 3.44Å; C382-M386 PolarHBondContact O-N 3.25Å
383	L	80.8	Confident	71.6	Confident	65 Å²	65	99.8 Å²	99.8	34%	0.34	48%	0.475	S	S	.	.	H	α-helix	trans	-61.9	-31.9	175.7	-69.7	-179.5	0	0	0	113.3	H379 D380 M385 M386	H379-L383 WeakPolarHBondContact CE1-CD1 3.22Å; H379-L383 PolarHBondContact O-N 2.84Å; D380-L383 PolarHBondContact O-N 3.4Å; L383-M385 VanDerWaalsContact C-N 3.3Å; L383-M386 HydrophobicContact CD2-SD 3.86Å; L383-M386 PolarHBondContact O-N 2.92Å
384	D	79.1	Confident	69.7	Low	107 Å²	107	94.5 Å²	94.5	57%	0.572	47%	0.469	S	S	*	.	H	α-helix	trans	-69.3	-27.9	174.4	-78.5	-12.2	0	0	0	112.9	D380 C382	D380-D384 PolarHBondContact O-N 2.92Å; C382-D384 VanDerWaalsContact C-N 3.26Å; C382-D384 PolarHBondContact O-N 3.12Å
385	M	74.3	Confident	67.9	Low	60 Å²	60	99.8 Å²	99.8	30%	0.296	50%	0.497	S	S	.	.	H	α-helix	trans	-86.5	-16.4	178.1	-66.6	-178.8	83.6	0	0	112.9	L104 M105 A381 C382 L383	L104-M385 HydrophobicContact CB-CE 3.68Å; L104-M385 HydrophobicContact CD1-CE 4.34Å; M105-M385 HydrophobicContact CB-SD 4.39Å; M105-M385 HydrophobicContact CG-SD 3.38Å; M105-M385 WeakPolarHBondContact CG-SD 3.4Å; A381-M385 WeakPolarHBondContact O-CG 3.31Å; A381-M385 PolarHBondContact O-N 2.97Å; C382-M385 PolarHBondContact O-N 3.44Å; L383-M385 VanDerWaalsContact C-N 3.3Å
386	M	76.3	Confident	66.4	Low	77 Å²	77	105 Å²	105	38%	0.379	52%	0.524	S	S	.	.	S	Bend	trans	-66.3	130.6	177.2	-70.2	-176.6	74.9	0	0	111	C382 L383 F390	C382-M386 PolarHBondContact O-N 3.25Å; L383-M386 HydrophobicContact CD2-SD 3.86Å; L383-M386 PolarHBondContact O-N 2.92Å; M386-F390 HydrophobicContact CE-CB 4.05Å
387	P	71.4	Confident	64.7	Low	74 Å²	74	103.6 Å²	103.6	48%	0.481	53%	0.531	S	S	.	.			trans	-53.7	142.8	176.5	-23.2	31.2	0	0	0	111.4	S389 F390	P387-S389 WeakPolarHBondContact CB-OG 3.29Å; P387-S389 PolarHBondContact O-N 2.75Å; P387-F390 PolarHBondContact O-N 3.02Å
388	K	57.7	Low	63.1	Low	191 Å²	191	99.1 Å²	99.1	83%	0.83	53%	0.529	S	S	*	.	G	3₁₀ helix	trans	-55.3	-23.8	178.3	-67.1	-177.1	-178.9	178.5	0	112.9	F390 K391	K388-F390 VanDerWaalsContact C-N 3.32Å; K388-F390 PolarHBondContact O-N 3.26Å; K388-K391 PolarHBondContact O-N 3.41Å
389	S	58.9	Low	61.4	Low	93 Å²	93	107.2 Å²	107.2	65%	0.65	57%	0.566	S	S	*	*	G	3₁₀ helix	trans	-67.8	-21	175.3	36.1	0	0	0	0	115	P387	P387-S389 WeakPolarHBondContact CB-OG 3.29Å; P387-S389 PolarHBondContact O-N 2.75Å
390	F	56.7	Low	59.5	Low	157 Å²	157	110.6 Å²	110.6	69%	0.689	59%	0.591	S	S	*	*	G	3₁₀ helix	trans	-96.8	-1.1	174.6	-84.2	-86.3	0	0	0	113.6	M386 P387 K388 F392	M386-F390 HydrophobicContact CE-CB 4.05Å; P387-F390 PolarHBondContact O-N 3.02Å; K388-F390 VanDerWaalsContact C-N 3.32Å; K388-F390 PolarHBondContact O-N 3.26Å; F390-F392 PolarHBondContact O-N 2.99Å
391	K	54.1	Low	57.7	Low	112 Å²	112	118.5 Å²	118.5	49%	0.487	62%	0.616	S	S	.	*			trans	-80.7	61.1	171.6	-69.7	-174.7	178.4	-178	0	110.5	K388	K388-K391 PolarHBondContact O-N 3.41Å
392	F	49.4	Very low	56	Low	191 Å²	191	128.7 Å²	128.7	84%	0.838	65%	0.652	S	S	*	*			trans	-86.8	-5	178.3	-124.6	-84	0	0	0	113.7	F390	F390-F392 PolarHBondContact O-N 2.99Å
393	L	46.5	Very low	54.2	Low	155 Å²	155	138.9 Å²	138.9	81%	0.812	69%	0.687	S	S	*	*	S	Bend	trans	-93.3	116.2	171.9	-88.9	147.5	0	0	0	109	Q395	L393-Q395 PolarHBondContact O-N 3.39Å
394	P	44.8	Very low	52.5	Low	111 Å²	111	142.8 Å²	142.8	72%	0.721	71%	0.706	S	S	*	*			trans	-60	128.9	175.6	24.5	-30.3	0	0	0	108.2	L396	P394-L396 VanDerWaalsContact C-N 3.34Å; P394-L396 PolarHBondContact O-N 2.88Å
395	Q	45	Very low	50.5	Low	174 Å²	174	148.1 Å²	148.1	81%	0.813	72%	0.719	S	S	*	*			trans	-61.1	101	167.7	-70.3	-171.1	-8.8	0	0	107.4	L393	L393-Q395 PolarHBondContact O-N 3.39Å
396	L	48.9	Very low	49	Very low	155 Å²	155	151.2 Å²	151.2	81%	0.812	74%	0.743	S	S	*	*			trans	-54.9	129.8	159.7	-88.7	137.2	0	0	0	106.7	P394 G398	P394-L396 VanDerWaalsContact C-N 3.34Å; P394-L396 PolarHBondContact O-N 2.88Å; L396-G398 PolarHBondContact O-N 3.15Å
397	P	40.9	Very low	47.3	Very low	125 Å²	125	152 Å²	152	81%	0.812	76%	0.757	S	S	*	*			trans	-57.1	104	-179.9	-13.3	22.2	0	0	0	108.2	H399	P397-H399 PolarHBondContact O-N 3.33Å; P397-H399 VanDerWaalsContact O-N 3.14Å
398	G	41.8	Very low	45.9	Very low	61 Å²	61	152.8 Å²	152.8	63%	0.629	77%	0.769	S	S	*	*			trans	-58.9	122.2	174.2	0	0	0	0	0	107	L396 T400	L396-G398 PolarHBondContact O-N 3.15Å; G398-T400 VanDerWaalsContact C-N 3.31Å; G398-T400 PolarHBondContact O-N 2.87Å; G398-T400 PolarHBondContact O-OG1 3.4Å
399	H	41.2	Very low	45.3	Very low	183 Å²	183	150.1 Å²	150.1	85%	0.847	77%	0.768	S	S	*	*			trans	-46.6	98.1	172.9	-144	-74.4	0	0	0	108.4	P397 R401	P397-H399 PolarHBondContact O-N 3.33Å; P397-H399 VanDerWaalsContact O-N 3.14Å; H399-R401 PolarHBondContact O-N 2.76Å
400	T	42.8	Very low	44.3	Very low	128 Å²	128	156.7 Å²	156.7	79%	0.785	78%	0.781	S	S	*	*			trans	-66.3	88.8	176.4	-28.3	0	0	0	0	105.1	G398 R402	G398-T400 VanDerWaalsContact C-N 3.31Å; G398-T400 PolarHBondContact O-N 2.87Å; G398-T400 PolarHBondContact O-OG1 3.4Å; T400-R402 PolarHBondContact O-N 2.96Å
401	R	45.7	Very low	43.4	Very low	233 Å²	233	155.4 Å²	155.4	88%	0.879	79%	0.785	S	S	*	*			trans	-63.4	91.6	164.6	-111.7	-170.4	-178.5	-161.1	1.6	105.1	H399 R403	H399-R401 PolarHBondContact O-N 2.76Å; R401-R403 PolarHBondContact O-N 2.87Å
402	R	40.1	Very low	42.4	Very low	225 Å²	225	155.4 Å²	155.4	85%	0.849	80%	0.798	S	S	*	*			trans	-43.4	114.8	167.9	-122.4	178.4	-179.8	175.8	0.2	105.8	T400 I404	T400-R402 PolarHBondContact O-N 2.96Å; R402-I404 PolarHBondContact O-N 2.86Å
403	R	43	Very low	41.6	Very low	240 Å²	240	149.9 Å²	149.9	91%	0.906	80%	0.795	S	S	*	*			trans	-67.2	90.6	171.8	-157.3	-179.3	-157	-174.7	4.3	105.4	R401 R405	R401-R403 PolarHBondContact O-N 2.87Å; R403-R405 PolarHBondContact O-N 2.83Å
404	I	43.3	Very low	41.2	Very low	146 Å²	146	151.2 Å²	151.2	75%	0.749	80%	0.797	S	S	*	*			trans	-57.7	111.7	171.9	-61.8	172.2	0	0	0	105.2	R402 P406	R402-I404 PolarHBondContact O-N 2.86Å; I404-P406 VanDerWaalsContact O-CD 3.31Å; I404-P406 WeakPolarHBondContact O-CD 3.39Å
405	R	37.1	Very low	41.1	Very low	219 Å²	219	154.8 Å²	154.8	83%	0.826	80%	0.804	S	S	*	*			trans	-69.8	114.4	168.7	-81.6	-179.4	171.8	-179.3	-2.9	106.6	R403 S407	R403-R405 PolarHBondContact O-N 2.83Å; R405-S407 PolarHBondContact O-N 3.07Å
406	P	42.5	Very low	40.8	Very low	125 Å²	125	157.8 Å²	157.8	81%	0.812	81%	0.808	S	S	*	*	S	Bend	trans	-84.3	66.6	176.7	34.7	-29.1	0	0	0	108.6	I404	I404-P406 VanDerWaalsContact O-CD 3.31Å; I404-P406 WeakPolarHBondContact O-CD 3.39Å
407	S	41.2	Very low	40.4	Very low	95 Å²	95	156.8 Å²	156.8	66%	0.664	81%	0.808	S	S	*	*			trans	-137.7	15.2	-176.6	-42.6	0	0	0	0	113.9	R405	R405-S407 PolarHBondContact O-N 3.07Å
408	A	43.2	Very low	40.7	Very low	90 Å²	90	157.6 Å²	157.6	74%	0.744	81%	0.811	S	S	*	*			trans	-136.7	65	174.4	0	0	0	0	0	110
409	V	43.5	Very low	40.9	Very low	134 Å²	134	164.6 Å²	164.6	81%	0.812	84%	0.841	S	S	*	*			trans	-137.8	86.4	155.2	-175.2	0	0	0	0	105.8
410	Y	37.7	Very low	40.9	Very low	232 Å²	232	163.7 Å²	163.7	91%	0.91	84%	0.84	S	S	*	*			trans	-105.3	140.5	156.9	-79.8	-81.7	0	0	0	108
411	V	38.3	Very low	40.8	Very low	129 Å²	129	165.6 Å²	165.6	78%	0.782	84%	0.843	S	S	*	*			trans	-79.4	147.2	-164.2	174.9	0	0	0	0	111.9
412	C	33.4	Very low	40.5	Very low	112 Å²	112	161.8 Å²	161.8	76%	0.757	84%	0.841	S	S	*	*				150.2	135.4	113.9	-152	0	0	0	0	112.5
413	G	32.7	Very low	40.5	Very low	75 Å²	75	158.1 Å²	158.1	77%	0.773	84%	0.841	S	S	*	*			trans	-169.2	61.4	170.8	0	0	0	0	0	108.8
414	E	39.1	Very low	40.4	Very low	183 Å²	183	153 Å²	153	86%	0.855	84%	0.837	S	S	*	*			trans	-74.7	127.6	172.5	-133.5	174.6	-171.7	0	0	109.3
415	H	42.5	Very low	40.2	Very low	186 Å²	186	153.5 Å²	153.5	86%	0.861	84%	0.843	S	S	*	*			trans	-60.1	133.6	172.3	-88.7	-77.8	0	0	0	111.2
416	R	37.7	Very low	40.4	Very low	237 Å²	237	148.8 Å²	148.8	89%	0.894	84%	0.844	S	S	*	*			trans	-117.3	118.1	151.6	-95.7	-175.8	171.5	175.9	-2.4	109.5
417	T	41.3	Very low	40.2	Very low	134 Å²	134	150.6 Å²	150.6	82%	0.822	85%	0.846	S	S	*	*			trans	-57.5	134.3	165.3	44.2	0	0	0	0	110.9
418	V	45.7	Very low	40.2	Very low	143 Å²	143	155.3 Å²	155.3	87%	0.867	86%	0.861	S	S	*	*			trans	-88.4	133.9	164.5	-178.6	0	0	0	0	107.4
419	V	46.7	Very low	39.9	Very low	208 Å²	208	161.2 Å²	161.2	100%	1.261	87%	0.872	S	S	*	*			trans	-64	0	172.8	172.7	0	0	0	0	110.9

Retrieved 419 of 419 residues in 303.3 ms (Link to these results)

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