A0A096NBV3_PAPAN Loading...

Protein-glutamine gamma-glutamyltransferase 5

Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.

AlphaFold DB , UniProt , Accession A0A096NBV3, Species PAPAN (Papio anubis, Olive baboon), Gene TGM5, Length 720 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M48.3Very low81.5Confident228 Ų22871.5 Ų71.5100%1.12341%0.405SS*.  0123.10-71.6-167.9-85.700107.1Q3M1-Q3 PolarHBondContact O-N 3.38Å
2A53.5Low82.8Confident58 Ų5867.8 Ų67.848%0.47938%0.383SS..PPolyproline II helixtrans-69.8117178.300000108.3
3Q65.4Low83.8Confident123 Ų12364.7 Ų64.758%0.57536%0.364SS*.PPolyproline II helixtrans-67.9145.5174.8-71176.2-14.300109.7M1 R48M1-Q3 PolarHBondContact O-N 3.38Å; Q3-R48 PolarHBondContact O-NE 2.6Å; Q3-R48 PolarHBondContact O-NH2 2.85Å
4G77Confident84.8Confident32 Ų3261.4 Ų61.433%0.3335%0.347SS..PPolyproline II helixtrans-60146.7173.800000111.5E6G4-E6 PolarHBondContact O-N 2.71Å
5L87.9Confident85.6Confident3 Ų362 Ų622%0.01636%0.357CS..PPolyproline II helixtrans-76.2121.4178.2-175.671000109.6F45 R48 F50 D55 I57 I121 S123L5-F45 HydrophobicContact CD1-CB 4.05Å; L5-F45 HydrophobicContact CD1-CD1 3.48Å; L5-F45 VanDerWaalsContact CD1-CD1 3.48Å; L5-F45 HydrophobicContact CD1-CD2 4.14Å; L5-F45 HydrophobicContact CD1-CE1 3.89Å; L5-F45 HydrophobicContact CD1-CE2 4.5Å; L5-F45 HydrophobicContact CD1-CG 3.61Å; L5-F45 HydrophobicContact CD1-CZ 4.38Å; L5-F45 HydrophobicContact CD2-CD1 4.1Å; L5-F45 HydrophobicContact CD2-CE1 3.65Å; L5-F45 HydrophobicContact CD2-CZ 4Å; L5-F45 HydrophobicContact CG-CD1 3.58Å; L5-F45 HydrophobicContact CG-CE1 3.66Å; L5-F45 HydrophobicContact CG-CG 4.25Å; L5-F45 HydrophobicContact CG-CZ 4.38Å; L5-R48 HydrophobicContact CD1-CG 4.39Å; L5-R48 WeakPolarHBondContact CD1-O 3.42Å; L5-F50 HydrophobicContact CD2-CB 4.2Å; L5-F50 HydrophobicContact CD2-CD2 3.83Å; L5-D55 HydrophobicContact CD2-CB 4.02Å; L5-I57 HydrophobicContact CD2-CD1 4.49Å; L5-I121 HydrophobicContact CB-CG2 3.96Å; L5-I121 HydrophobicContact CD2-CD1 4.34Å; L5-I121 HydrophobicContact CD2-CG2 4.03Å; L5-I121 HydrophobicContact CG-CD1 4.45Å; L5-I121 HydrophobicContact CG-CG2 4.37Å; L5-S123 PolarHBondContact N-OG 2.74Å
6E90.1Very high86.3Confident74 Ų7465 Ų6535%0.34636%0.36SS..  trans-123.9128.7-173.9-171.6-172.4166.500110.9G4 F45 R46 N47 Y131G4-E6 PolarHBondContact O-N 2.71Å; E6-F45 CarbonylContact O-C 3.58Å; E6-F45 WeakPolarHBondContact O-CA 3.45Å; E6-F45 WeakPolarHBondContact O-CB 3.46Å; E6-R46 PolarHBondContact O-N 3.49Å; E6-R46 WeakPolarHBondContact OE1-CD 3.47Å; E6-R46 IonicContact OE1-NE 2.78Å; E6-N47 PolarHBondContact OE2-ND2 3.13Å; E6-N47 VanDerWaalsContact OE2-ND2 3.11Å; E6-Y131 WeakPolarHBondContact CG-OH 3.42Å
7V93.1Very high87Confident15 Ų1561.2 Ų61.29%0.09134%0.339CS..EExtended strand (participates in β ladder)trans-82124.1-177.7-1780000109.7F45 I119 I121 Y131V7-F45 HydrophobicContact CG2-CD1 4.25Å; V7-F45 HydrophobicContact CG2-CE1 4.05Å; V7-I119 HydrophobicContact CG2-CD1 3.83Å; V7-I121 HydrophobicContact CG2-CD1 3.52Å; V7-Y131 HydrophobicContact CB-CD1 4.04Å; V7-Y131 HydrophobicContact CB-CD2 4.19Å; V7-Y131 HydrophobicContact CB-CE1 4.05Å; V7-Y131 HydrophobicContact CB-CE2 4.21Å; V7-Y131 HydrophobicContact CB-CG 4.12Å; V7-Y131 HydrophobicContact CG2-CD2 3.77Å; V7-Y131 HydrophobicContact CG2-CE2 3.8Å; V7-Y131 HydrophobicContact CG2-CG 4.15Å
8A93.8Very high87.6Confident44 Ų4457.8 Ų57.836%0.36432%0.32SS..EExtended strand (participates in β ladder)trans-89.1-47.617700000112Y44 R46A8-Y44 WeakPolarHBondContact CB-O 3.34Å; A8-Y44 PolarHBondContact N-O 2.8Å; A8-R46 HydrophobicContact CB-CB 4.48Å; A8-R46 HydrophobicContact CB-CG 3.46Å; A8-R46 VanDerWaalsContact CB-CG 3.46Å
9L94.8Very high88.2Confident108 Ų10858.8 Ų58.857%0.56533%0.328SS*.EExtended strand (participates in β ladder)trans-152.4149.8-172.6176.268.3000108.9Y44L9-Y44 HydrophobicContact CB-CD2 4.22Å; L9-Y44 HydrophobicContact CD2-CD2 4.15Å; L9-Y44 HydrophobicContact CD2-CE2 4.48Å; L9-Y44 HydrophobicContact CG-CD2 4.24Å; L9-Y44 PolarHBondContact N-O 2.84Å; L9-Y44 PolarHBondContact O-N 2.75Å
10T96Very high88.7Confident32 Ų3261.6 Ų61.620%0.19633%0.333CS..EExtended strand (participates in β ladder)trans-123.5132.6169.2-61.10000109.6L12 L41 T42 L43 L133T10-L12 HydrophobicContact CG2-CD2 4.05Å; T10-L41 HydrophobicContact CG2-CD1 4.44Å; T10-T42 WeakPolarHBondContact CA-O 3.48Å; T10-L43 HydrophobicContact CG2-CD2 4Å; T10-L133 HydrophobicContact CG2-CB 4.22Å; T10-L133 HydrophobicContact CG2-CD1 4.26Å; T10-L133 HydrophobicContact CG2-CD2 4.48Å; T10-L133 WeakPolarHBondContact OG1-CD2 3.35Å
11D96.8Very high89.2Confident69 Ų6958.6 Ų58.637%0.36932%0.317SS..EExtended strand (participates in β ladder)trans-110.8114.8169.9178.95.6000108.3Q13 L41 T42 Y44D11-Q13 PolarHBondContact O-N 3.12Å; D11-Q13 WeakPolarHBondContact OD1-CA 3.47Å; D11-Q13 PolarHBondContact OD1-N 3.34Å; D11-L41 CarbonylContact O-C 3.56Å; D11-L41 WeakPolarHBondContact O-CA 3.31Å; D11-L41 WeakPolarHBondContact O-CB 3.23Å; D11-T42 PolarHBondContact N-O 3.39Å; D11-T42 PolarHBondContact O-N 3.5Å; D11-Y44 HydrophobicContact CB-CE2 4.13Å
12L96.9Very high91.5Very high28 Ų2850.2 Ų50.215%0.14728%0.275CS..  trans-77.4-0178.4-64.7-178.2000112.9T10 S14 N17 L31 L41 L117T10-L12 HydrophobicContact CG2-CD2 4.05Å; L12-S14 PolarHBondContact O-N 2.89Å; L12-S14 VanDerWaalsContact O-N 3.11Å; L12-N17 PolarHBondContact O-ND2 2.93Å; L12-L31 HydrophobicContact CB-CB 4.38Å; L12-L31 HydrophobicContact CB-CD2 4.11Å; L12-L31 HydrophobicContact CD1-CB 4.32Å; L12-L31 HydrophobicContact CD1-CD2 4.42Å; L12-L31 HydrophobicContact CD2-CD2 4.5Å; L12-L41 HydrophobicContact CD2-CB 4.37Å; L12-L41 HydrophobicContact CD2-CD2 4.45Å; L12-L117 HydrophobicContact CD2-CD2 4.28Å
13Q96.6Very high93.7Very high27 Ų2747.5 Ų47.513%0.12625%0.253CS..  trans48.837.9-178.1-57.9-168.56.800113D11 S15 R16 N17 T42 E101D11-Q13 PolarHBondContact O-N 3.12Å; D11-Q13 WeakPolarHBondContact OD1-CA 3.47Å; D11-Q13 PolarHBondContact OD1-N 3.34Å; Q13-S15 PolarHBondContact O-N 2.92Å; Q13-R16 PolarHBondContact O-N 2.82Å; Q13-R16 VanDerWaalsContact O-N 3.13Å; Q13-N17 PolarHBondContact O-N 2.95Å; Q13-N17 PolarHBondContact O-ND2 3.39Å; Q13-T42 PolarHBondContact NE2-OG1 2.86Å; Q13-E101 PolarHBondContact NE2-OE1 3.25Å; Q13-E101 PolarHBondContact OE1-OE1 2.94Å
14S97.4Very high95.1Very high19 Ų1944.8 Ų44.813%0.13324%0.24CC..Hα-helixtrans-49.9-52.1-168.4-57.30000112.8L12 R16 N17 N18 D29 L31L12-S14 PolarHBondContact O-N 2.89Å; L12-S14 VanDerWaalsContact O-N 3.11Å; S14-R16 PolarHBondContact O-N 3.36Å; S14-N17 PolarHBondContact O-N 3.22Å; S14-N18 VanDerWaalsContact O-CB 3.3Å; S14-N18 WeakPolarHBondContact O-CB 3.32Å; S14-N18 PolarHBondContact O-N 2.93Å; S14-N18 PolarHBondContact O-OD1 3.2Å; S14-N18 VanDerWaalsContact O-OD1 3.07Å; S14-D29 PolarHBondContact OG-O 2.96Å; S14-L31 PolarHBondContact OG-N 3.32Å
15S96.6Very high96Very high70 Ų7045.5 Ų45.549%0.4924%0.235SC..Hα-helixtrans-58.1-47.3-178.5176.20000112.8Q13 V19 V28Q13-S15 PolarHBondContact O-N 2.92Å; S15-V19 WeakPolarHBondContact O-CG2 3.46Å; S15-V19 PolarHBondContact O-N 3.46Å; S15-V28 PolarHBondContact N-O 2.7Å
16R96.8Very high96.4Very high110 Ų11046.6 Ų46.642%0.41524%0.24SC..Hα-helixtrans-66.9-42.2-179.3-177.1-173.9179.5-160.34.8111.6Q13 S14 R20 E101Q13-R16 PolarHBondContact O-N 2.82Å; Q13-R16 VanDerWaalsContact O-N 3.13Å; S14-R16 PolarHBondContact O-N 3.36Å; R16-R20 VanDerWaalsContact NH2-NH2 3.18Å; R16-R20 WeakPolarHBondContact O-CG 3.36Å; R16-R20 PolarHBondContact O-N 2.89Å; R16-E101 IonicContact NH1-OE1 3.42Å; R16-E101 PolarHBondContact NH1-OE1 2.9Å
17N98.4Very high96.5Very high0 Ų044.4 Ų44.40%023%0.232CC..Hα-helixtrans-66.5-46.3178.3-74-39000110.9L12 Q13 S14 V19 R20 H21 L31 V33 F39 N40L12-N17 PolarHBondContact O-ND2 2.93Å; Q13-N17 PolarHBondContact O-N 2.95Å; Q13-N17 PolarHBondContact O-ND2 3.39Å; S14-N17 PolarHBondContact O-N 3.22Å; N17-V19 VanDerWaalsContact C-N 3.29Å; N17-V19 PolarHBondContact O-N 3.24Å; N17-R20 CarbonylContact O-C 3.56Å; N17-R20 WeakPolarHBondContact O-CA 3.41Å; N17-R20 WeakPolarHBondContact O-CB 3.28Å; N17-R20 PolarHBondContact O-N 3.26Å; N17-H21 WeakPolarHBondContact O-CB 3.36Å; N17-H21 PolarHBondContact O-CD2 3.15Å; N17-H21 PolarHBondContact O-N 3.15Å; N17-L31 HydrophobicContact CB-CD1 3.54Å; N17-V33 HydrophobicContact CB-CG1 4.34Å; N17-F39 HydrophobicContact CB-CB 4.37Å; N17-N40 PolarHBondContact ND2-O 2.9Å; N17-N40 PolarHBondContact OD1-N 3Å
18N98.5Very high96.4Very high0 Ų047.2 Ų47.20%025%0.249CC..Hα-helixtrans-60.6-40-176.8-68.48.1000111.9S14 R20 H21 H22 T23 E24 T27 H30 L32S14-N18 VanDerWaalsContact O-CB 3.3Å; S14-N18 WeakPolarHBondContact O-CB 3.32Å; S14-N18 PolarHBondContact O-N 2.93Å; S14-N18 PolarHBondContact O-OD1 3.2Å; S14-N18 VanDerWaalsContact O-OD1 3.07Å; N18-R20 PolarHBondContact O-N 2.94Å; N18-H21 CarbonylContact O-C 3.58Å; N18-H21 PolarHBondContact O-N 2.82Å; N18-H22 PolarHBondContact O-N 2.7Å; N18-T23 WeakPolarHBondContact CA-OG1 3.34Å; N18-T23 WeakPolarHBondContact CB-OG1 3.2Å; N18-T23 PolarHBondContact O-N 3.44Å; N18-T23 PolarHBondContact O-OG1 3.4Å; N18-E24 HydrophobicContact CB-CB 4.36Å; N18-E24 PolarHBondContact O-N 2.88Å; N18-T27 PolarHBondContact ND2-O 2.86Å; N18-H30 PolarHBondContact ND2-O 3.17Å; N18-L32 PolarHBondContact OD1-N 3.02Å; N18-L32 PolarHBondContact OD1-O 2.96Å; N18-L32 VanDerWaalsContact OD1-O 3.09Å
19V97.9Very high96.2Very high78 Ų7851.1 Ų51.147%0.47326%0.264SS..Hα-helixtrans-60.4-44.8173.1172.50000111.7S15 N17 H21 H22 E24S15-V19 WeakPolarHBondContact O-CG2 3.46Å; S15-V19 PolarHBondContact O-N 3.46Å; N17-V19 VanDerWaalsContact C-N 3.29Å; N17-V19 PolarHBondContact O-N 3.24Å; V19-H21 PolarHBondContact O-N 3.2Å; V19-H22 PolarHBondContact O-N 3.3Å; V19-E24 HydrophobicContact CG2-CB 3.9Å; V19-E24 HydrophobicContact CG2-CG 4.18Å
20R98.1Very high96.2Very high113 Ų11352.2 Ų52.243%0.42627%0.266SS..Hα-helixtrans-66.8-27.3178-73.2177.7170.5-175.1-6.2113R16 N17 N18 Q37 N40R16-R20 VanDerWaalsContact NH2-NH2 3.18Å; R16-R20 WeakPolarHBondContact O-CG 3.36Å; R16-R20 PolarHBondContact O-N 2.89Å; N17-R20 CarbonylContact O-C 3.56Å; N17-R20 WeakPolarHBondContact O-CA 3.41Å; N17-R20 WeakPolarHBondContact O-CB 3.28Å; N17-R20 PolarHBondContact O-N 3.26Å; N18-R20 PolarHBondContact O-N 2.94Å; R20-Q37 PolarHBondContact O-NE2 3.37Å; R20-N40 PolarHBondContact NH1-OD1 2.97Å
21H98.6Very high96.3Very high0 Ų050.9 Ų50.90%026%0.257CS..THydrogen-bonded Turntrans-98.64.3-178.3-77.7-89.6000113.4N17 N18 V19 T23 R34 Q37 A38N17-H21 WeakPolarHBondContact O-CB 3.36Å; N17-H21 PolarHBondContact O-CD2 3.15Å; N17-H21 PolarHBondContact O-N 3.15Å; N18-H21 CarbonylContact O-C 3.58Å; N18-H21 PolarHBondContact O-N 2.82Å; V19-H21 PolarHBondContact O-N 3.2Å; H21-T23 HydrophobicContact CB-CG2 4.45Å; H21-T23 PolarHBondContact O-N 3.03Å; H21-R34 HydrophobicContact CB-CG 4.43Å; H21-R34 PolarHBondContact CE1-O 3.42Å; H21-R34 PolarHBondContact ND1-N 2.96Å; H21-R34 WeakPolarHBondContact O-CD 3.45Å; H21-R34 PolarHBondContact O-NE 2.91Å; H21-Q37 WeakPolarHBondContact CE1-CG 3.14Å; H21-Q37 PolarHBondContact ND1-OE1 3.23Å; H21-A38 PolarHBondContact NE2-O 2.95Å
22H98.3Very high96.4Very high52 Ų5247.7 Ų47.724%0.24124%0.24CC..THydrogen-bonded Turntrans56.248.5-178.6-48.1-71000112.2N18 V19 E24 R34 W143 M162N18-H22 PolarHBondContact O-N 2.7Å; V19-H22 PolarHBondContact O-N 3.3Å; H22-E24 VanDerWaalsContact CA-OE2 3.29Å; H22-E24 WeakPolarHBondContact CA-OE2 3.17Å; H22-R34 PolarHBondContact O-NH2 2.94Å; H22-W143 HydrophobicContact CB-CH2 3.9Å; H22-W143 HydrophobicContact CB-CZ2 4.16Å; H22-W143 HydrophobicContact CB-CZ3 4.1Å; H22-W143 AromaticContact CD2-CD2 3.49Å; H22-W143 VanDerWaalsContact CD2-CD2 3.49Å; H22-W143 AromaticContact CD2-CE2 3.48Å; H22-W143 VanDerWaalsContact CD2-CE2 3.48Å; H22-W143 AromaticContact CD2-CE3 3.85Å; H22-W143 AromaticContact CD2-CG 3.92Å; H22-W143 AromaticContact CD2-CZ2 3.89Å; H22-W143 AromaticContact CD2-NE1 3.8Å; H22-W143 AromaticContact CG-CE2 3.99Å; H22-W143 AromaticContact CG-CZ2 3.93Å; H22-W143 AromaticContact NE2-CD1 3.75Å; H22-W143 AromaticContact NE2-CE2 3.81Å; H22-W143 AromaticContact NE2-NE1 3.62Å; H22-M162 HydrophobicContact CB-CE 4.4Å; H22-M162 HydrophobicContact CB-SD 4.27Å
23T98.4Very high96.5Very high1 Ų146.4 Ų46.41%0.00623%0.233CC..  trans-131.72.9-179.555.40000112.9N18 H21 E25 I26 T27 L32 R34 L139N18-T23 WeakPolarHBondContact CA-OG1 3.34Å; N18-T23 WeakPolarHBondContact CB-OG1 3.2Å; N18-T23 PolarHBondContact O-N 3.44Å; N18-T23 PolarHBondContact O-OG1 3.4Å; H21-T23 HydrophobicContact CB-CG2 4.45Å; H21-T23 PolarHBondContact O-N 3.03Å; T23-E25 PolarHBondContact O-N 3.17Å; T23-I26 HydrophobicContact CG2-CD1 4.42Å; T23-I26 WeakPolarHBondContact O-CB 2.8Å; T23-I26 PolarHBondContact O-N 2.84Å; T23-T27 PolarHBondContact O-N 3.39Å; T23-L32 HydrophobicContact CG2-CB 4.18Å; T23-L32 PolarHBondContact OG1-O 3.38Å; T23-R34 HydrophobicContact CG2-CG 4.37Å; T23-L139 HydrophobicContact CG2-CD1 4.13Å
24E96.4Very high96.6Very high65 Ų6545.2 Ų45.230%0.30423%0.228SC..THydrogen-bonded Turntrans-61.5-29178.572.1-78.2-167.700113.1N18 V19 H22 I26N18-E24 HydrophobicContact CB-CB 4.36Å; N18-E24 PolarHBondContact O-N 2.88Å; V19-E24 HydrophobicContact CG2-CB 3.9Å; V19-E24 HydrophobicContact CG2-CG 4.18Å; H22-E24 VanDerWaalsContact CA-OE2 3.29Å; H22-E24 WeakPolarHBondContact CA-OE2 3.17Å; E24-I26 PolarHBondContact O-N 3.15Å
25E95.5Very high96.7Very high47 Ų4744.4 Ų44.422%0.2222%0.222CC..THydrogen-bonded Turntrans-65.7-25174.4-81.1-71.8172.800112.5T23 M162 F186 K690 R694T23-E25 PolarHBondContact O-N 3.17Å; E25-M162 HydrophobicContact CG-CE 4.45Å; E25-F186 HydrophobicContact CB-CB 4.2Å; E25-F186 HydrophobicContact CB-CD2 3.57Å; E25-F186 HydrophobicContact CB-CE2 3.96Å; E25-F186 HydrophobicContact CB-CG 3.86Å; E25-F186 HydrophobicContact CG-CD2 4.22Å; E25-F186 HydrophobicContact CG-CE2 4.41Å; E25-K690 PolarHBondContact O-NZ 2.91Å; E25-K690 WeakPolarHBondContact OE2-CD 3.45Å; E25-K690 WeakPolarHBondContact OE2-CE 3.16Å; E25-K690 IonicContact OE2-NZ 2.72Å; E25-K690 PolarHBondContact OE2-NZ 2.83Å; E25-R694 IonicContact OE1-NH2 3.3Å; E25-R694 PolarHBondContact OE1-NH2 2.91Å; E25-R694 IonicContact OE2-NH2 3.4Å; E25-R694 PolarHBondContact OE2-NH2 2.98Å
26I95.6Very high96.7Very high27 Ų2742 Ų4214%0.13821%0.208CC..THydrogen-bonded Turntrans-80.2-49.3177.7-57.6167000110T23 E24 L32 L139 F186 I191T23-I26 HydrophobicContact CG2-CD1 4.42Å; T23-I26 WeakPolarHBondContact O-CB 2.8Å; T23-I26 PolarHBondContact O-N 2.84Å; E24-I26 PolarHBondContact O-N 3.15Å; I26-L32 HydrophobicContact CB-CD2 3.81Å; I26-L32 HydrophobicContact CD1-CD2 3.74Å; I26-L32 HydrophobicContact CG1-CD2 4.37Å; I26-L32 HydrophobicContact CG2-CD2 3.45Å; I26-L32 VanDerWaalsContact CG2-CD2 3.45Å; I26-L139 HydrophobicContact CD1-CD1 4.23Å; I26-F186 HydrophobicContact CD1-CD1 4.21Å; I26-F186 HydrophobicContact CD1-CE1 4.33Å; I26-F186 HydrophobicContact CG1-CD1 3.46Å; I26-F186 VanDerWaalsContact CG1-CD1 3.46Å; I26-F186 HydrophobicContact CG1-CE1 4Å; I26-F186 HydrophobicContact CG1-CG 4.29Å; I26-I191 HydrophobicContact CG2-CB 4.15Å; I26-I191 HydrophobicContact CG2-CG2 3.75Å
27T93.2Very high96.8Very high27 Ų2739.2 Ų39.217%0.16620%0.2CC..  trans-166.8156.8179.9-179.30000110.7N18 T23 D29 H30 L32N18-T27 PolarHBondContact ND2-O 2.86Å; T23-T27 PolarHBondContact O-N 3.39Å; T27-D29 PolarHBondContact OG1-N 3.41Å; T27-D29 VanDerWaalsContact OG1-N 3.14Å; T27-H30 HydrophobicContact CG2-CB 4.05Å; T27-L32 HydrophobicContact CG2-CD1 3.28Å; T27-L32 HydrophobicContact CG2-CD2 4.14Å; T27-L32 HydrophobicContact CG2-CG 4.24Å
28V89.8Confident96.8Very high74 Ų7440.6 Ų40.645%0.44821%0.212SC..SBendtrans-110-11.4170.4-64.90000112.8S15S15-V28 PolarHBondContact N-O 2.7Å
29D90.2Very high96.8Very high126 Ų12640.7 Ų40.767%0.67421%0.212SC*.SBendtrans-92.8-40.4-171.9-57.8-49.9000112S14 T27S14-D29 PolarHBondContact OG-O 2.96Å; T27-D29 PolarHBondContact OG1-N 3.41Å; T27-D29 VanDerWaalsContact OG1-N 3.14Å
30H94.6Very high96.8Very high132 Ų13237.3 Ų37.361%0.61119%0.191SC*.SBendtrans-99145.9179.4-57.9-74.9000111.3N18 T27 L32N18-H30 PolarHBondContact ND2-O 3.17Å; T27-H30 HydrophobicContact CG2-CB 4.05Å; H30-L32 HydrophobicContact CB-CD1 3.87Å; H30-L32 WeakPolarHBondContact O-CD1 3.42Å; H30-L32 PolarHBondContact O-N 2.8Å
31L98.3Very high96.8Very high3 Ų332 Ų322%0.01617%0.171CC..EExtended strand (participates in β ladder)trans-76.3112.8178.8-17963.8000110.3L12 S14 N17 V33 F39 F136 I137L12-L31 HydrophobicContact CB-CB 4.38Å; L12-L31 HydrophobicContact CB-CD2 4.11Å; L12-L31 HydrophobicContact CD1-CB 4.32Å; L12-L31 HydrophobicContact CD1-CD2 4.42Å; L12-L31 HydrophobicContact CD2-CD2 4.5Å; S14-L31 PolarHBondContact OG-N 3.32Å; N17-L31 HydrophobicContact CB-CD1 3.54Å; L31-V33 HydrophobicContact CD1-CG1 3.59Å; L31-V33 HydrophobicContact CG-CG1 4.03Å; L31-F39 HydrophobicContact CD2-CD2 3.85Å; L31-F39 HydrophobicContact CD2-CE2 3.87Å; L31-F136 HydrophobicContact CB-CB 3.91Å; L31-F136 HydrophobicContact CD2-CB 3.73Å; L31-F136 HydrophobicContact CD2-CG 4.35Å; L31-F136 HydrophobicContact CG-CB 3.81Å; L31-F136 VanDerWaalsContact O-CA 3.3Å; L31-F136 WeakPolarHBondContact O-CA 3.41Å; L31-F136 WeakPolarHBondContact O-CB 3.46Å; L31-I137 PolarHBondContact O-N 2.6Å
32L98.4Very high96.7Very high3 Ų332.5 Ų32.52%0.01617%0.174CC..EExtended strand (participates in β ladder)trans-122.1116.1174.6-81.271000108.6N18 T23 I26 T27 H30 I137 I191N18-L32 PolarHBondContact OD1-N 3.02Å; N18-L32 PolarHBondContact OD1-O 2.96Å; N18-L32 VanDerWaalsContact OD1-O 3.09Å; T23-L32 HydrophobicContact CG2-CB 4.18Å; T23-L32 PolarHBondContact OG1-O 3.38Å; I26-L32 HydrophobicContact CB-CD2 3.81Å; I26-L32 HydrophobicContact CD1-CD2 3.74Å; I26-L32 HydrophobicContact CG1-CD2 4.37Å; I26-L32 HydrophobicContact CG2-CD2 3.45Å; I26-L32 VanDerWaalsContact CG2-CD2 3.45Å; T27-L32 HydrophobicContact CG2-CD1 3.28Å; T27-L32 HydrophobicContact CG2-CD2 4.14Å; T27-L32 HydrophobicContact CG2-CG 4.24Å; H30-L32 HydrophobicContact CB-CD1 3.87Å; H30-L32 WeakPolarHBondContact O-CD1 3.42Å; H30-L32 PolarHBondContact O-N 2.8Å; L32-I137 HydrophobicContact CD1-CD1 4.37Å; L32-I137 HydrophobicContact CG-CB 4.09Å; L32-I137 HydrophobicContact CG-CD1 4.26Å; L32-I191 HydrophobicContact CD2-CG1 4.41Å
33V98.8Very high96.7Very high0 Ų030 Ų300%016%0.163CC..EExtended strand (participates in β ladder)trans-128.9162.8-174.7-66.90000110.7N17 L31 F39 F136 I137 L138 L139N17-V33 HydrophobicContact CB-CG1 4.34Å; L31-V33 HydrophobicContact CD1-CG1 3.59Å; L31-V33 HydrophobicContact CG-CG1 4.03Å; V33-F39 HydrophobicContact CB-CD1 4.3Å; V33-F39 HydrophobicContact CG1-CB 3.75Å; V33-F39 HydrophobicContact CG1-CD1 4.22Å; V33-F39 HydrophobicContact CG1-CG 3.95Å; V33-F39 HydrophobicContact CG2-CD1 4Å; V33-F39 HydrophobicContact CG2-CE1 4.15Å; V33-F39 HydrophobicContact CG2-CG 4.45Å; V33-F136 HydrophobicContact CG2-CD2 3.72Å; V33-F136 HydrophobicContact CG2-CE2 4.16Å; V33-I137 PolarHBondContact N-O 2.83Å; V33-L138 HydrophobicContact CG2-CD1 3.81Å; V33-L138 CarbonylContact O-C 3.6Å; V33-L138 WeakPolarHBondContact O-CA 3.38Å; V33-L139 PolarHBondContact O-N 2.68Å
34R98.9Very high96.6Very high2 Ų234.1 Ų34.11%0.00818%0.179CC..EExtended strand (participates in β ladder)trans-110138.2178.4-56.8-174.6-178.1-83.7-2.1109.5H21 H22 T23 L139 F140 N141H21-R34 HydrophobicContact CB-CG 4.43Å; H21-R34 PolarHBondContact CE1-O 3.42Å; H21-R34 PolarHBondContact ND1-N 2.96Å; H21-R34 WeakPolarHBondContact O-CD 3.45Å; H21-R34 PolarHBondContact O-NE 2.91Å; H22-R34 PolarHBondContact O-NH2 2.94Å; T23-R34 HydrophobicContact CG2-CG 4.37Å; R34-L139 WeakPolarHBondContact CA-O 3.48Å; R34-L139 HydrophobicContact CG-CB 4.34Å; R34-F140 PolarHBondContact NH1-O 3.08Å; R34-N141 HydrophobicContact CB-CB 3.64Å
35R98.8Very high96.5Very high2 Ų231.5 Ų31.51%0.00817%0.167CC..THydrogen-bonded Turntrans-59.9157.8-179.168.7-170.9-172.3162.310.8112.6Q37 A106 P108 A110 L138 L139 F140 N141 D147 G216R35-Q37 PolarHBondContact O-N 3.43Å; R35-A106 HydrophobicContact CB-CB 4.49Å; R35-P108 WeakPolarHBondContact CD-O 3.44Å; R35-P108 PolarHBondContact NE-O 3.22Å; R35-P108 PolarHBondContact NH1-O 2.98Å; R35-P108 PolarHBondContact NH2-O 3.4Å; R35-A110 HydrophobicContact CB-CB 4.37Å; R35-A110 WeakPolarHBondContact CD-O 3.27Å; R35-A110 PolarHBondContact NH1-O 2.8Å; R35-L138 HydrophobicContact CB-CD1 4.09Å; R35-L138 HydrophobicContact CB-CD2 4.04Å; R35-L138 HydrophobicContact CB-CG 4.03Å; R35-L139 PolarHBondContact N-O 2.94Å; R35-F140 VanDerWaalsContact CZ-CE1 3.43Å; R35-F140 VanDerWaalsContact NH2-CE1 3.28Å; R35-N141 HydrophobicContact CG-CB 4.33Å; R35-N141 WeakPolarHBondContact O-CB 3.28Å; R35-N141 PolarHBondContact O-ND2 3.16Å; R35-D147 VanDerWaalsContact CG-OD2 3.32Å; R35-D147 WeakPolarHBondContact CG-OD2 3.19Å; R35-D147 IonicContact CZ-OD1 3.35Å; R35-D147 IonicContact CZ-OD2 3.21Å; R35-D147 IonicContact NE-OD1 3.68Å; R35-D147 PolarHBondContact NE-OD1 3.33Å; R35-D147 IonicContact NE-OD2 3.83Å; R35-D147 PolarHBondContact NE-OD2 3.2Å; R35-D147 IonicContact NH2-OD1 3.65Å; R35-D147 PolarHBondContact NH2-OD1 2.78Å; R35-D147 IonicContact NH2-OD2 2.92Å; R35-G216 PolarHBondContact NH1-O 2.81Å
36G98.4Very high96.3Very high20 Ų2037 Ų3721%0.20619%0.185CC..THydrogen-bonded Turntrans71.43.9-178.400000115.2A106G36-A106 WeakPolarHBondContact CA-O 3.33Å; G36-A106 PolarHBondContact N-O 3.39Å
37Q98.6Very high95.9Very high51 Ų5139.2 Ų39.224%0.23820%0.197CC..SBendtrans-129142.8177.7-179.8-179.1-4.300110.2R20 H21 R35 N141R20-Q37 PolarHBondContact O-NE2 3.37Å; H21-Q37 WeakPolarHBondContact CE1-CG 3.14Å; H21-Q37 PolarHBondContact ND1-OE1 3.23Å; R35-Q37 PolarHBondContact O-N 3.43Å; Q37-N141 WeakPolarHBondContact CB-ND2 3.49Å; Q37-N141 PolarHBondContact OE1-ND2 2.59Å
38A98.3Very high95.7Very high30 Ų3040 Ų4025%0.24820%0.197CC..EExtended strand (participates in β ladder)trans-78140.3-176.800000112.3H21 W91 L104 C105H21-A38 PolarHBondContact NE2-O 2.95Å; A38-W91 HydrophobicContact CB-CH2 3.46Å; A38-W91 VanDerWaalsContact CB-CH2 3.46Å; A38-W91 HydrophobicContact CB-CZ2 3.73Å; A38-L104 CarbonylContact C-O 3.47Å; A38-L104 VanDerWaalsContact CA-O 3.26Å; A38-L104 WeakPolarHBondContact CA-O 3.37Å; A38-C105 HydrophobicContact CB-CB 4.27Å
39F98.5Very high95.7Very high1 Ų136.8 Ų36.80%0.00418%0.18CC..EExtended strand (participates in β ladder)trans-127.7150.4171.465.1-86.6000111.1N17 L31 V33 S103 L104 F136N17-F39 HydrophobicContact CB-CB 4.37Å; L31-F39 HydrophobicContact CD2-CD2 3.85Å; L31-F39 HydrophobicContact CD2-CE2 3.87Å; V33-F39 HydrophobicContact CB-CD1 4.3Å; V33-F39 HydrophobicContact CG1-CB 3.75Å; V33-F39 HydrophobicContact CG1-CD1 4.22Å; V33-F39 HydrophobicContact CG1-CG 3.95Å; V33-F39 HydrophobicContact CG2-CD1 4Å; V33-F39 HydrophobicContact CG2-CE1 4.15Å; V33-F39 HydrophobicContact CG2-CG 4.45Å; F39-S103 WeakPolarHBondContact O-CA 3.24Å; F39-L104 HydrophobicContact CD1-CB 4.45Å; F39-L104 WeakPolarHBondContact CD1-O 3.35Å; F39-L104 HydrophobicContact CE1-CB 3.92Å; F39-L104 HydrophobicContact CE2-CB 4.05Å; F39-L104 HydrophobicContact CE2-CD2 4.23Å; F39-L104 HydrophobicContact CZ-CB 3.71Å; F39-L104 HydrophobicContact CZ-CD2 4.06Å; F39-L104 HydrophobicContact CZ-CG 4.49Å; F39-L104 PolarHBondContact N-O 3.14Å; F39-L104 PolarHBondContact O-N 2.86Å; F39-F136 HydrophobicContact CZ-CE2 4.38Å; F39-F136 HydrophobicContact CZ-CZ 4.3Å
40N97.7Very high95.8Very high8 Ų831.2 Ų31.24%0.04315%0.15CC..EExtended strand (participates in β ladder)trans-99.2147.7-172.6-66.291.3000111.8N17 R20 V102 S103N17-N40 PolarHBondContact ND2-O 2.9Å; N17-N40 PolarHBondContact OD1-N 3Å; R20-N40 PolarHBondContact NH1-OD1 2.97Å; N40-V102 CarbonylContact C-O 3.53Å; N40-V102 WeakPolarHBondContact CA-O 3.36Å; N40-S103 PolarHBondContact ND2-OG 3.04Å
41L97.4Very high95.6Very high0 Ų029 Ų290%014%0.139CC..EExtended strand (participates in β ladder)trans-141.9154.4162.966.388.4000110.4T10 D11 L12 L43 E101 V102 L104 L117T10-L41 HydrophobicContact CG2-CD1 4.44Å; D11-L41 CarbonylContact O-C 3.56Å; D11-L41 WeakPolarHBondContact O-CA 3.31Å; D11-L41 WeakPolarHBondContact O-CB 3.23Å; L12-L41 HydrophobicContact CD2-CB 4.37Å; L12-L41 HydrophobicContact CD2-CD2 4.45Å; L41-L43 HydrophobicContact CD1-CD1 4.41Å; L41-L43 HydrophobicContact CD1-CD2 3.6Å; L41-L43 HydrophobicContact CD1-CG 3.68Å; L41-E101 WeakPolarHBondContact O-CA 3.35Å; L41-V102 HydrophobicContact CD1-CG2 3.39Å; L41-V102 HydrophobicContact CD2-CG2 4.4Å; L41-V102 HydrophobicContact CG-CG2 3.57Å; L41-V102 PolarHBondContact N-O 2.8Å; L41-V102 PolarHBondContact O-N 2.89Å; L41-L104 HydrophobicContact CD2-CD1 3.55Å; L41-L104 HydrophobicContact CD2-CD2 3.98Å; L41-L104 HydrophobicContact CD2-CG 4.45Å; L41-L104 HydrophobicContact CG-CD1 3.91Å; L41-L117 HydrophobicContact CD2-CD2 3.59Å
42T97.8Very high95.1Very high11 Ų1132.7 Ų32.77%0.06716%0.164CC..EExtended strand (participates in β ladder)trans-114.8124177.5-54.70000110.3T10 D11 Q13 Y44 T100T10-T42 WeakPolarHBondContact CA-O 3.48Å; D11-T42 PolarHBondContact N-O 3.39Å; D11-T42 PolarHBondContact O-N 3.5Å; Q13-T42 PolarHBondContact NE2-OG1 2.86Å; T42-Y44 HydrophobicContact CG2-CD2 4.15Å; T42-Y44 HydrophobicContact CG2-CE1 4.22Å; T42-Y44 HydrophobicContact CG2-CE2 3.6Å; T42-T100 WeakPolarHBondContact CA-O 3.33Å
43L97.2Very high94.4Very high0 Ų036.2 Ų36.20%020%0.2CC..EExtended strand (participates in β ladder)trans-97.2124.1172.4-58.6176.3000108.7T10 L41 F45 I57 S99 T100 I119 L133T10-L43 HydrophobicContact CG2-CD2 4Å; L41-L43 HydrophobicContact CD1-CD1 4.41Å; L41-L43 HydrophobicContact CD1-CD2 3.6Å; L41-L43 HydrophobicContact CD1-CG 3.68Å; L43-F45 HydrophobicContact CB-CE1 4.2Å; L43-F45 HydrophobicContact CB-CE2 4.13Å; L43-F45 HydrophobicContact CB-CZ 3.69Å; L43-F45 HydrophobicContact CD1-CZ 4.24Å; L43-I57 HydrophobicContact CD1-CD1 3.89Å; L43-I57 HydrophobicContact CD1-CG2 4.49Å; L43-S99 CarbonylContact O-C 3.49Å; L43-S99 WeakPolarHBondContact O-CA 3.18Å; L43-T100 PolarHBondContact N-O 3.44Å; L43-T100 PolarHBondContact O-N 2.87Å; L43-I119 HydrophobicContact CD1-CD1 4.14Å; L43-I119 HydrophobicContact CD2-CD1 4.24Å; L43-L133 HydrophobicContact CD2-CD1 3.84Å; L43-L133 HydrophobicContact CD2-CD2 4.36Å
44Y96.8Very high93.8Very high88 Ų8839.8 Ų39.835%0.34522%0.219SC..EExtended strand (participates in β ladder)trans-102.6137171.8-64-89.6000109.3A8 L9 D11 T42A8-Y44 WeakPolarHBondContact CB-O 3.34Å; A8-Y44 PolarHBondContact N-O 2.8Å; L9-Y44 HydrophobicContact CB-CD2 4.22Å; L9-Y44 HydrophobicContact CD2-CD2 4.15Å; L9-Y44 HydrophobicContact CD2-CE2 4.48Å; L9-Y44 HydrophobicContact CG-CD2 4.24Å; L9-Y44 PolarHBondContact N-O 2.84Å; L9-Y44 PolarHBondContact O-N 2.75Å; D11-Y44 HydrophobicContact CB-CE2 4.13Å; T42-Y44 HydrophobicContact CG2-CD2 4.15Å; T42-Y44 HydrophobicContact CG2-CE1 4.22Å; T42-Y44 HydrophobicContact CG2-CE2 3.6Å
45F94.3Very high93.4Very high10 Ų1039.9 Ų39.94%0.04422%0.22CC..EExtended strand (participates in β ladder)trans-114.4145.2-175.1-55.5-75.9000111.9L5 E6 V7 L43 R48 F50 I57 T98 T100 I121L5-F45 HydrophobicContact CD1-CB 4.05Å; L5-F45 HydrophobicContact CD1-CD1 3.48Å; L5-F45 VanDerWaalsContact CD1-CD1 3.48Å; L5-F45 HydrophobicContact CD1-CD2 4.14Å; L5-F45 HydrophobicContact CD1-CE1 3.89Å; L5-F45 HydrophobicContact CD1-CE2 4.5Å; L5-F45 HydrophobicContact CD1-CG 3.61Å; L5-F45 HydrophobicContact CD1-CZ 4.38Å; L5-F45 HydrophobicContact CD2-CD1 4.1Å; L5-F45 HydrophobicContact CD2-CE1 3.65Å; L5-F45 HydrophobicContact CD2-CZ 4Å; L5-F45 HydrophobicContact CG-CD1 3.58Å; L5-F45 HydrophobicContact CG-CE1 3.66Å; L5-F45 HydrophobicContact CG-CG 4.25Å; L5-F45 HydrophobicContact CG-CZ 4.38Å; E6-F45 CarbonylContact O-C 3.58Å; E6-F45 WeakPolarHBondContact O-CA 3.45Å; E6-F45 WeakPolarHBondContact O-CB 3.46Å; V7-F45 HydrophobicContact CG2-CD1 4.25Å; V7-F45 HydrophobicContact CG2-CE1 4.05Å; L43-F45 HydrophobicContact CB-CE1 4.2Å; L43-F45 HydrophobicContact CB-CE2 4.13Å; L43-F45 HydrophobicContact CB-CZ 3.69Å; L43-F45 HydrophobicContact CD1-CZ 4.24Å; F45-R48 WeakPolarHBondContact CB-O 3.28Å; F45-F50 HydrophobicContact CE2-CB 4.02Å; F45-F50 HydrophobicContact CZ-CB 4.21Å; F45-I57 HydrophobicContact CZ-CD1 4.16Å; F45-T98 PolarHBondContact N-O 2.94Å; F45-T100 WeakPolarHBondContact CE2-OG1 3.34Å; F45-I121 HydrophobicContact CE1-CD1 4.33Å
46R90.7Very high93Very high161 Ų16141.4 Ų41.461%0.60823%0.228SC*.SBendtrans-75.4-44.3-178.2-68.3-170.4-177.8-102.2-4.6113.3E6 A8E6-R46 PolarHBondContact O-N 3.49Å; E6-R46 WeakPolarHBondContact OE1-CD 3.47Å; E6-R46 IonicContact OE1-NE 2.78Å; A8-R46 HydrophobicContact CB-CB 4.48Å; A8-R46 HydrophobicContact CB-CG 3.46Å; A8-R46 VanDerWaalsContact CB-CG 3.46Å
47N86.8Confident92.7Very high74 Ų7440.5 Ų40.540%0.39622%0.218SC..SBendtrans-102.5-46.4-161.8-56.3-31.4000112.3E6E6-N47 PolarHBondContact OE2-ND2 3.13Å; E6-N47 VanDerWaalsContact OE2-ND2 3.11Å
48R89.8Confident92.5Very high43 Ų4340.1 Ų40.116%0.16222%0.218CC..  trans-157.216317963.2175-177.581-2.7110.6Q3 L5 F45 D55Q3-R48 PolarHBondContact O-NE 2.6Å; Q3-R48 PolarHBondContact O-NH2 2.85Å; L5-R48 HydrophobicContact CD1-CG 4.39Å; L5-R48 WeakPolarHBondContact CD1-O 3.42Å; F45-R48 WeakPolarHBondContact CB-O 3.28Å; R48-D55 IonicContact CZ-OD1 3.11Å; R48-D55 IonicContact CZ-OD2 2.91Å; R48-D55 IonicContact NH1-OD1 3.26Å; R48-D55 IonicContact NH1-OD2 3.92Å; R48-D55 PolarHBondContact NH1-OD2 2.88Å; R48-D55 VanDerWaalsContact NH2-CG 3.32Å; R48-D55 IonicContact NH2-OD1 2.75Å; R48-D55 PolarHBondContact NH2-OD1 3.07Å; R48-D55 IonicContact NH2-OD2 2.65Å; R48-D55 PolarHBondContact NH2-OD2 3.14Å; R48-D55 VanDerWaalsContact NH2-OD2 3.17Å
49G89.6Confident92.4Very high8 Ų838.7 Ų38.78%0.08221%0.206CC..  trans-70.3163.1172.300000113.8A97G49-A97 VanDerWaalsContact CA-O 3.22Å; G49-A97 WeakPolarHBondContact CA-O 2.86Å; G49-A97 PolarHBondContact N-O 2.84Å
50F91.9Very high92.4Very high9 Ų938.7 Ų38.74%0.03921%0.206CC..  trans-63.1131175.1172.9-111.2000111L5 F45 P52 D55 I57 L79 N95 T100L5-F50 HydrophobicContact CD2-CB 4.2Å; L5-F50 HydrophobicContact CD2-CD2 3.83Å; F45-F50 HydrophobicContact CE2-CB 4.02Å; F45-F50 HydrophobicContact CZ-CB 4.21Å; F50-P52 HydrophobicContact CD1-CG 4.21Å; F50-P52 HydrophobicContact CE1-CB 4.41Å; F50-P52 HydrophobicContact CE1-CG 3.79Å; F50-D55 HydrophobicContact CD2-CB 3.59Å; F50-D55 HydrophobicContact CE2-CB 3.55Å; F50-D55 WeakPolarHBondContact CE2-O 3.42Å; F50-I57 HydrophobicContact CD2-CD1 3.68Å; F50-I57 HydrophobicContact CD2-CG1 3.96Å; F50-I57 HydrophobicContact CE2-CD1 3.95Å; F50-I57 HydrophobicContact CE2-CG1 3.84Å; F50-I57 HydrophobicContact CG-CD1 4.27Å; F50-L79 HydrophobicContact CD1-CD2 4.31Å; F50-L79 HydrophobicContact CE1-CD2 3.67Å; F50-L79 HydrophobicContact CE2-CD2 4.32Å; F50-L79 HydrophobicContact CZ-CD2 3.7Å; F50-N95 PolarHBondContact O-ND2 3.22Å; F50-N95 PolarHBondContact O-OD1 3.47Å; F50-T100 HydrophobicContact CB-CG2 4.46Å; F50-T100 VanDerWaalsContact CB-OG1 3.28Å; F50-T100 WeakPolarHBondContact CB-OG1 3.43Å; F50-T100 HydrophobicContact CD1-CG2 4.26Å
51Q90.6Very high92.4Very high84 Ų8438.4 Ų38.439%0.39320%0.204SC..  trans-116.2104.4178.7-71-178-1900110.3G53 L54 D55Q51-G53 PolarHBondContact O-N 3.28Å; Q51-L54 HydrophobicContact CB-CB 4.03Å; Q51-L54 HydrophobicContact CB-CD1 4.19Å; Q51-L54 PolarHBondContact O-N 3.09Å; Q51-D55 PolarHBondContact N-OD2 2.89Å; Q51-D55 PolarHBondContact O-N 3.47Å
52P87.3Confident92.4Very high82 Ų8239.9 Ų39.953%0.53221%0.212SC..BIsolated β-bridgetrans-52.9132175.6-25.532.8000111.9F50 L54 L92F50-P52 HydrophobicContact CD1-CG 4.21Å; F50-P52 HydrophobicContact CE1-CB 4.41Å; F50-P52 HydrophobicContact CE1-CG 3.79Å; P52-L54 VanDerWaalsContact C-N 3.27Å; P52-L54 PolarHBondContact O-N 2.83Å; P52-L92 HydrophobicContact CG-CD2 4.49Å
53G83.9Confident92.5Very high76 Ų7639.8 Ų39.878%0.78421%0.211SC*.THydrogen-bonded Turntrans86.5-18.8-177.900000114.9Q51Q51-G53 PolarHBondContact O-N 3.28Å
54L87.6Confident92.5Very high76 Ų7641.2 Ų41.240%0.39823%0.226SC..THydrogen-bonded Turntrans-104.9-30171.6-67.3175.7000112.5Q51 P52 F124Q51-L54 HydrophobicContact CB-CB 4.03Å; Q51-L54 HydrophobicContact CB-CD1 4.19Å; Q51-L54 PolarHBondContact O-N 3.09Å; P52-L54 VanDerWaalsContact C-N 3.27Å; P52-L54 PolarHBondContact O-N 2.83Å; L54-F124 HydrophobicContact CD2-CB 4.17Å; L54-F124 HydrophobicContact CD2-CD1 4.26Å; L54-F124 HydrophobicContact CD2-CG 4.18Å; L54-F124 WeakPolarHBondContact O-CB 3.18Å; L54-F124 PolarHBondContact O-N 2.86Å
55D89.6Confident92.5Very high4 Ų440.7 Ų40.72%0.02123%0.233CC..EExtended strand (participates in β ladder)trans-117.5144.1174.8-57.1-54.4000110.5L5 R48 F50 Q51 D122 S123L5-D55 HydrophobicContact CD2-CB 4.02Å; R48-D55 IonicContact CZ-OD1 3.11Å; R48-D55 IonicContact CZ-OD2 2.91Å; R48-D55 IonicContact NH1-OD1 3.26Å; R48-D55 IonicContact NH1-OD2 3.92Å; R48-D55 PolarHBondContact NH1-OD2 2.88Å; R48-D55 VanDerWaalsContact NH2-CG 3.32Å; R48-D55 IonicContact NH2-OD1 2.75Å; R48-D55 PolarHBondContact NH2-OD1 3.07Å; R48-D55 IonicContact NH2-OD2 2.65Å; R48-D55 PolarHBondContact NH2-OD2 3.14Å; R48-D55 VanDerWaalsContact NH2-OD2 3.17Å; F50-D55 HydrophobicContact CD2-CB 3.59Å; F50-D55 HydrophobicContact CE2-CB 3.55Å; F50-D55 WeakPolarHBondContact CE2-O 3.42Å; Q51-D55 PolarHBondContact N-OD2 2.89Å; Q51-D55 PolarHBondContact O-N 3.47Å; D55-D122 CarbonylContact C-O 3.54Å; D55-D122 WeakPolarHBondContact CA-O 3.46Å; D55-S123 WeakPolarHBondContact OD1-CB 3.33Å; D55-S123 PolarHBondContact OD1-OG 2.91Å
56N89.9Confident92.6Very high34 Ų3445 Ų4518%0.18226%0.256CS..EExtended strand (participates in β ladder)trans-126.6115.4171.2-179.730.4000109.3S78 D122N56-S78 PolarHBondContact OD1-OG 2.99Å; N56-D122 HydrophobicContact CB-CB 4.34Å; N56-D122 PolarHBondContact N-O 2.96Å; N56-D122 PolarHBondContact O-N 2.87Å
57I93Very high92.9Very high0 Ų039.6 Ų39.60%024%0.242CC..EExtended strand (participates in β ladder)trans-93.1119.8173.3-58.3176.7000107.8L5 L43 F45 F50 F59 S78 L79 I119 I121L5-I57 HydrophobicContact CD2-CD1 4.49Å; L43-I57 HydrophobicContact CD1-CD1 3.89Å; L43-I57 HydrophobicContact CD1-CG2 4.49Å; F45-I57 HydrophobicContact CZ-CD1 4.16Å; F50-I57 HydrophobicContact CD2-CD1 3.68Å; F50-I57 HydrophobicContact CD2-CG1 3.96Å; F50-I57 HydrophobicContact CE2-CD1 3.95Å; F50-I57 HydrophobicContact CE2-CG1 3.84Å; F50-I57 HydrophobicContact CG-CD1 4.27Å; I57-F59 HydrophobicContact CG2-CD2 4.46Å; I57-F59 HydrophobicContact CG2-CE1 4.28Å; I57-F59 HydrophobicContact CG2-CE2 3.89Å; I57-F59 HydrophobicContact CG2-CZ 3.77Å; I57-S78 WeakPolarHBondContact O-CA 3.37Å; I57-L79 HydrophobicContact CB-CB 4.27Å; I57-L79 HydrophobicContact CB-CD2 4.4Å; I57-L79 HydrophobicContact CD1-CD2 4.18Å; I57-L79 PolarHBondContact O-N 2.92Å; I57-I119 HydrophobicContact CG2-CB 4.2Å; I57-I119 HydrophobicContact CG2-CD1 4.46Å; I57-I119 HydrophobicContact CG2-CG2 4.02Å; I57-I121 HydrophobicContact CG1-CG1 4.35Å
58I94.1Very high93.4Very high43 Ų4339.2 Ų39.222%0.22124%0.24CC..EExtended strand (participates in β ladder)trans-110.8114.6179-54.2171.5000107.5V76 F77 I119 H120I58-V76 HydrophobicContact CG2-CG1 3.48Å; I58-V76 VanDerWaalsContact CG2-CG1 3.48Å; I58-F77 CarbonylContact C-O 3.56Å; I58-F77 WeakPolarHBondContact CA-O 3.17Å; I58-I119 CarbonylContact O-C 3.57Å; I58-I119 VanDerWaalsContact O-CA 3.23Å; I58-I119 WeakPolarHBondContact O-CA 3.41Å; I58-H120 HydrophobicContact CB-CB 4.24Å; I58-H120 PolarHBondContact N-O 2.94Å; I58-H120 PolarHBondContact O-N 2.62Å
59F96.5Very high93.6Very high0 Ų041.9 Ų41.90%026%0.256CS..EExtended strand (participates in β ladder)trans-81.5143173.9-60.9-87.2000110.8I57 V76 F77 L79 A90 V102 L104 L117 K118 I119I57-F59 HydrophobicContact CG2-CD2 4.46Å; I57-F59 HydrophobicContact CG2-CE1 4.28Å; I57-F59 HydrophobicContact CG2-CE2 3.89Å; I57-F59 HydrophobicContact CG2-CZ 3.77Å; F59-V76 VanDerWaalsContact O-CA 3.31Å; F59-V76 WeakPolarHBondContact O-CA 3.13Å; F59-F77 HydrophobicContact CB-CD1 4.19Å; F59-F77 HydrophobicContact CB-CD2 3.95Å; F59-F77 HydrophobicContact CB-CE1 3.83Å; F59-F77 HydrophobicContact CB-CE2 3.59Å; F59-F77 HydrophobicContact CB-CG 4.23Å; F59-F77 HydrophobicContact CB-CZ 3.52Å; F59-F77 HydrophobicContact CD2-CD2 4.15Å; F59-F77 HydrophobicContact CD2-CE2 4.03Å; F59-F77 HydrophobicContact CG-CD2 4.37Å; F59-F77 AromaticContact CG-CE2 3.92Å; F59-F77 HydrophobicContact CG-CE2 3.92Å; F59-F77 HydrophobicContact CG-CZ 4.22Å; F59-F77 PolarHBondContact N-O 2.7Å; F59-F77 PolarHBondContact O-N 2.87Å; F59-L79 HydrophobicContact CE2-CB 4.21Å; F59-L79 HydrophobicContact CE2-CD1 4.43Å; F59-A90 HydrophobicContact CD2-CB 3.7Å; F59-A90 HydrophobicContact CE2-CB 3.61Å; F59-V102 HydrophobicContact CE1-CG2 4.34Å; F59-V102 HydrophobicContact CZ-CB 4.45Å; F59-V102 HydrophobicContact CZ-CG2 3.9Å; F59-L104 HydrophobicContact CD1-CD2 3.89Å; F59-L104 HydrophobicContact CD1-CG 4.48Å; F59-L104 HydrophobicContact CE1-CD1 4.16Å; F59-L104 HydrophobicContact CE1-CD2 4.22Å; F59-L104 HydrophobicContact CE1-CG 4.5Å; F59-L104 HydrophobicContact CG-CD2 4.37Å; F59-L104 HydrophobicContact CZ-CD1 4.34Å; F59-L117 HydrophobicContact CD1-CD1 4.23Å; F59-K118 WeakPolarHBondContact CA-O 3.47Å; F59-I119 HydrophobicContact CD1-CG2 3.3Å; F59-I119 HydrophobicContact CE1-CG2 3.51Å; F59-I119 HydrophobicContact CG-CG2 4.07Å; F59-I119 HydrophobicContact CZ-CG2 4.4Å
60V97.3Very high93.8Very high2 Ų246.1 Ų46.11%0.01229%0.291CS..EExtended strand (participates in β ladder)trans-128.7123.7170.1-173.20000108E62 R74 A75 V76 K118 H120V60-E62 HydrophobicContact CG1-CG 4.22Å; V60-R74 HydrophobicContact CG1-CG 4.46Å; V60-A75 WeakPolarHBondContact CA-O 3.12Å; V60-V76 HydrophobicContact CG1-CG2 4.15Å; V60-V76 HydrophobicContact CG2-CG1 4.42Å; V60-V76 HydrophobicContact CG2-CG2 4.09Å; V60-K118 HydrophobicContact CB-CB 4.25Å; V60-K118 PolarHBondContact N-O 3.08Å; V60-K118 PolarHBondContact O-N 2.64Å; V60-H120 VanDerWaalsContact CG2-CD2 3.47Å; V60-H120 WeakPolarHBondContact CG2-CD2 3.29Å
61V98.2Very high93.9Very high1 Ų149.8 Ų49.81%0.00631%0.31CS..EExtended strand (participates in β ladder)trans-117.6137174.2-630000109.7R74 A75 F77 W88 Y115 L116 L117 F136V61-R74 CarbonylContact O-C 3.55Å; V61-R74 VanDerWaalsContact O-CA 3.27Å; V61-R74 WeakPolarHBondContact O-CA 3.45Å; V61-A75 HydrophobicContact CG2-CB 3.75Å; V61-A75 PolarHBondContact N-O 3.29Å; V61-A75 PolarHBondContact O-N 2.81Å; V61-F77 HydrophobicContact CG1-CE1 4.02Å; V61-F77 HydrophobicContact CG1-CZ 4.14Å; V61-F77 HydrophobicContact CG2-CE1 3.95Å; V61-W88 HydrophobicContact CB-CH2 4.46Å; V61-W88 HydrophobicContact CB-CZ3 4.47Å; V61-W88 HydrophobicContact CG1-CE3 4.4Å; V61-W88 HydrophobicContact CG1-CZ3 4.13Å; V61-W88 HydrophobicContact CG2-CD2 3.82Å; V61-W88 HydrophobicContact CG2-CE3 3.96Å; V61-W88 HydrophobicContact CG2-CG 4.42Å; V61-W88 HydrophobicContact CG2-CH2 4.01Å; V61-W88 HydrophobicContact CG2-CZ2 3.88Å; V61-W88 HydrophobicContact CG2-CZ3 4.04Å; V61-Y115 HydrophobicContact CB-CD1 4.06Å; V61-Y115 HydrophobicContact CG2-CD1 4.46Å; V61-L116 WeakPolarHBondContact CA-O 3.45Å; V61-L117 HydrophobicContact CG1-CD1 3.56Å; V61-F136 HydrophobicContact CG1-CE1 4.27Å; V61-F136 HydrophobicContact CG1-CZ 4.36Å
62E98.5Very high94.1Very high32 Ų3247.5 Ų47.515%0.1531%0.31CS..EExtended strand (participates in β ladder)trans-137.9133.5-174.1-74.5169.8170.500110.2V60 P67 T73 R74 Y115 L116 K118V60-E62 HydrophobicContact CG1-CG 4.22Å; E62-P67 HydrophobicContact CB-CB 3.81Å; E62-P67 HydrophobicContact CB-CG 3.82Å; E62-P67 HydrophobicContact CG-CB 3.79Å; E62-P67 HydrophobicContact CG-CG 4.17Å; E62-T73 CarbonylContact C-O 3.59Å; E62-T73 WeakPolarHBondContact CA-O 3.32Å; E62-R74 HydrophobicContact CG-CB 4.21Å; E62-R74 HydrophobicContact CG-CG 3.73Å; E62-R74 WeakPolarHBondContact OE1-CD 3.49Å; E62-R74 IonicContact OE1-CZ 3.17Å; E62-R74 IonicContact OE1-NE 2.67Å; E62-R74 PolarHBondContact OE1-NE 2.75Å; E62-R74 IonicContact OE1-NH2 2.7Å; E62-Y115 CarbonylContact O-C 3.56Å; E62-Y115 VanDerWaalsContact O-CA 3.28Å; E62-Y115 WeakPolarHBondContact O-CA 3.34Å; E62-L116 PolarHBondContact N-O 3.33Å; E62-L116 VanDerWaalsContact N-O 3.09Å; E62-L116 PolarHBondContact O-N 2.9Å; E62-K118 IonicContact OE2-NZ 2.71Å; E62-K118 PolarHBondContact OE2-NZ 3.09Å
63T98.4Very high94.6Very high9 Ų943.7 Ų43.76%0.05529%0.285CS..EExtended strand (participates in β ladder)trans-130.5153173.8-175.20000110.9T73 A111 R114 Y115T63-T73 HydrophobicContact CG2-CG2 4.05Å; T63-T73 PolarHBondContact N-O 2.77Å; T63-A111 HydrophobicContact CG2-CB 4.39Å; T63-R114 WeakPolarHBondContact CB-O 3.47Å; T63-R114 PolarHBondContact OG1-O 2.96Å; T63-Y115 HydrophobicContact CG2-CD1 4.28Å; T63-Y115 HydrophobicContact CG2-CE1 3.56Å; T63-Y115 HydrophobicContact CG2-CE2 4Å; T63-Y115 WeakPolarHBondContact CG2-OH 3.27Å
64G96.9Very high95.3Very high30 Ų3043.9 Ų43.931%0.30926%0.262SS..SBendtrans75.6171.4-177.700000113.9L66G64-L66 VanDerWaalsContact C-N 3.3Å; G64-L66 PolarHBondContact O-N 2.88Å
65P96.8Very high95.7Very high76 Ų7640.6 Ų40.649%0.49425%0.246SC..SBendtrans-75.8-19.3-177.630.8-35.6000113.3F204 P208P65-F204 HydrophobicContact CG-CE2 4.19Å; P65-F204 HydrophobicContact CG-CZ 4.02Å; P65-P208 HydrophobicContact CG-CB 3.78Å; P65-P208 HydrophobicContact CG-CG 4.34Å
66L96.9Very high96Very high102 Ų10242.9 Ų42.953%0.53426%0.26SS..SBendtrans-129.872.6-179.6-62.4173.2000110.2G64 D68 P208 A209G64-L66 VanDerWaalsContact C-N 3.3Å; G64-L66 PolarHBondContact O-N 2.88Å; L66-D68 PolarHBondContact O-N 3.01Å; L66-P208 HydrophobicContact CD1-CG 4.35Å; L66-A209 HydrophobicContact CB-CB 4.04Å; L66-A209 HydrophobicContact CD1-CB 4.1Å
67P96.9Very high96.2Very high47 Ų4741.4 Ų41.431%0.30525%0.252SS..  trans-66.6130-178.3-18.131.6000112E62 R74E62-P67 HydrophobicContact CB-CB 3.81Å; E62-P67 HydrophobicContact CB-CG 3.82Å; E62-P67 HydrophobicContact CG-CB 3.79Å; E62-P67 HydrophobicContact CG-CG 4.17Å; P67-R74 HydrophobicContact CB-CB 3.97Å
68D96.7Very high96.1Very high66 Ų6642 Ų4235%0.35326%0.256SS..  trans-136138.1-175.3-177-87.1000112.1L66 A70 L71 G72 T73 R74L66-D68 PolarHBondContact O-N 3.01Å; D68-A70 WeakPolarHBondContact OD1-CA 3.44Å; D68-A70 WeakPolarHBondContact OD1-CB 3.35Å; D68-A70 PolarHBondContact OD1-N 2.87Å; D68-L71 HydrophobicContact CB-CB 4.1Å; D68-L71 HydrophobicContact CB-CD1 4.09Å; D68-L71 HydrophobicContact CB-CG 4.13Å; D68-L71 PolarHBondContact OD1-N 2.84Å; D68-G72 PolarHBondContact O-N 2.72Å; D68-T73 PolarHBondContact N-OG1 2.58Å; D68-T73 PolarHBondContact O-N 2.96Å; D68-T73 VanDerWaalsContact O-N 3.11Å; D68-T73 PolarHBondContact O-OG1 2.81Å; D68-R74 PolarHBondContact O-N 3.15Å
69L94.9Very high95.8Very high98 Ų9840.8 Ų40.851%0.51325%0.25SC..THydrogen-bonded Turntrans-70.6-39.3-176.8-79.7166.5000112.5G72 R74 V76L69-G72 PolarHBondContact O-N 2.65Å; L69-R74 HydrophobicContact CD2-CB 4.42Å; L69-R74 HydrophobicContact CD2-CG 4.08Å; L69-R74 HydrophobicContact CG-CB 4.41Å; L69-R74 HydrophobicContact CG-CG 4.2Å; L69-V76 HydrophobicContact CD2-CG2 4.02Å
70A93.9Very high94.5Very high98 Ų9843.6 Ų43.681%0.8127%0.273SS*.THydrogen-bonded Turntrans-75.8-33.8-177.600000111.6D68 G72D68-A70 WeakPolarHBondContact OD1-CA 3.44Å; D68-A70 WeakPolarHBondContact OD1-CB 3.35Å; D68-A70 PolarHBondContact OD1-N 2.87Å; A70-G72 VanDerWaalsContact C-N 3.29Å
71L93.7Very high92.7Very high85 Ų8552 Ų5245%0.44531%0.305SS..THydrogen-bonded Turntrans-79.2-10.7175.1-60.5-178.9000113.5D68 T73 A209 A213D68-L71 HydrophobicContact CB-CB 4.1Å; D68-L71 HydrophobicContact CB-CD1 4.09Å; D68-L71 HydrophobicContact CB-CG 4.13Å; D68-L71 PolarHBondContact OD1-N 2.84Å; L71-T73 VanDerWaalsContact C-N 3.3Å; L71-T73 PolarHBondContact O-N 2.97Å; L71-A209 HydrophobicContact CD1-CB 4.37Å; L71-A213 HydrophobicContact CB-CB 3.88Å
72G94.9Very high90.5Very high37 Ų3760.3 Ų60.338%0.38134%0.343SS..THydrogen-bonded Turntrans78.28.4178.900000114.9D68 L69 A70 R74D68-G72 PolarHBondContact O-N 2.72Å; L69-G72 PolarHBondContact O-N 2.65Å; A70-G72 VanDerWaalsContact C-N 3.29Å; G72-R74 VanDerWaalsContact C-N 3.29Å
73T97.8Very high88.3Confident1 Ų167.4 Ų67.41%0.00638%0.376CS..SBendtrans-83.5-7172.152.60000112.6E62 T63 D68 L71 C212 A213E62-T73 CarbonylContact C-O 3.59Å; E62-T73 WeakPolarHBondContact CA-O 3.32Å; T63-T73 HydrophobicContact CG2-CG2 4.05Å; T63-T73 PolarHBondContact N-O 2.77Å; D68-T73 PolarHBondContact N-OG1 2.58Å; D68-T73 PolarHBondContact O-N 2.96Å; D68-T73 VanDerWaalsContact O-N 3.11Å; D68-T73 PolarHBondContact O-OG1 2.81Å; L71-T73 VanDerWaalsContact C-N 3.3Å; L71-T73 PolarHBondContact O-N 2.97Å; T73-C212 HydrophobicContact CG2-CB 4.1Å; T73-A213 HydrophobicContact CG2-CB 4.03Å
74R97.9Very high86.3Confident80 Ų8068.9 Ų68.930%0.30239%0.387SS..EExtended strand (participates in β ladder)trans-128.7138.8166.2-177.9171.4-173.5-126.8-4.5109.8V60 V61 E62 P67 D68 L69 G72V60-R74 HydrophobicContact CG1-CG 4.46Å; V61-R74 CarbonylContact O-C 3.55Å; V61-R74 VanDerWaalsContact O-CA 3.27Å; V61-R74 WeakPolarHBondContact O-CA 3.45Å; E62-R74 HydrophobicContact CG-CB 4.21Å; E62-R74 HydrophobicContact CG-CG 3.73Å; E62-R74 WeakPolarHBondContact OE1-CD 3.49Å; E62-R74 IonicContact OE1-CZ 3.17Å; E62-R74 IonicContact OE1-NE 2.67Å; E62-R74 PolarHBondContact OE1-NE 2.75Å; E62-R74 IonicContact OE1-NH2 2.7Å; P67-R74 HydrophobicContact CB-CB 3.97Å; D68-R74 PolarHBondContact O-N 3.15Å; L69-R74 HydrophobicContact CD2-CB 4.42Å; L69-R74 HydrophobicContact CD2-CG 4.08Å; L69-R74 HydrophobicContact CG-CB 4.41Å; L69-R74 HydrophobicContact CG-CG 4.2Å; G72-R74 VanDerWaalsContact C-N 3.29Å
75A96.6Very high85.1Confident7 Ų773.9 Ų73.96%0.05841%0.414CS..EExtended strand (participates in β ladder)trans-136.9144.217200000111.8V60 V61 F77 W88V60-A75 WeakPolarHBondContact CA-O 3.12Å; V61-A75 HydrophobicContact CG2-CB 3.75Å; V61-A75 PolarHBondContact N-O 3.29Å; V61-A75 PolarHBondContact O-N 2.81Å; A75-F77 HydrophobicContact CB-CD1 4.42Å; A75-W88 HydrophobicContact CB-CB 4.24Å; A75-W88 HydrophobicContact CB-CD2 4.44Å; A75-W88 HydrophobicContact CB-CG 3.78Å
76V95.3Very high84.5Confident52 Ų5271.2 Ų71.232%0.31540%0.396SS..EExtended strand (participates in β ladder)trans-127.6121.3179.7-179.20000108.7I58 F59 V60 L69 S86I58-V76 HydrophobicContact CG2-CG1 3.48Å; I58-V76 VanDerWaalsContact CG2-CG1 3.48Å; F59-V76 VanDerWaalsContact O-CA 3.31Å; F59-V76 WeakPolarHBondContact O-CA 3.13Å; V60-V76 HydrophobicContact CG1-CG2 4.15Å; V60-V76 HydrophobicContact CG2-CG1 4.42Å; V60-V76 HydrophobicContact CG2-CG2 4.09Å; L69-V76 HydrophobicContact CD2-CG2 4.02Å; V76-S86 WeakPolarHBondContact O-CB 3.34Å
77F94.1Very high84.1Confident3 Ų370.5 Ų70.51%0.01340%0.398CS..EExtended strand (participates in β ladder)trans-147.8150.8-173.653.5-76.4000111.3I58 F59 V61 A75 W88 A90 L104I58-F77 CarbonylContact C-O 3.56Å; I58-F77 WeakPolarHBondContact CA-O 3.17Å; F59-F77 HydrophobicContact CB-CD1 4.19Å; F59-F77 HydrophobicContact CB-CD2 3.95Å; F59-F77 HydrophobicContact CB-CE1 3.83Å; F59-F77 HydrophobicContact CB-CE2 3.59Å; F59-F77 HydrophobicContact CB-CG 4.23Å; F59-F77 HydrophobicContact CB-CZ 3.52Å; F59-F77 HydrophobicContact CD2-CD2 4.15Å; F59-F77 HydrophobicContact CD2-CE2 4.03Å; F59-F77 HydrophobicContact CG-CD2 4.37Å; F59-F77 AromaticContact CG-CE2 3.92Å; F59-F77 HydrophobicContact CG-CE2 3.92Å; F59-F77 HydrophobicContact CG-CZ 4.22Å; F59-F77 PolarHBondContact N-O 2.7Å; F59-F77 PolarHBondContact O-N 2.87Å; V61-F77 HydrophobicContact CG1-CE1 4.02Å; V61-F77 HydrophobicContact CG1-CZ 4.14Å; V61-F77 HydrophobicContact CG2-CE1 3.95Å; A75-F77 HydrophobicContact CB-CD1 4.42Å; F77-W88 VanDerWaalsContact CB-O 3.3Å; F77-W88 WeakPolarHBondContact CB-O 3.33Å; F77-W88 HydrophobicContact CD1-CB 3.48Å; F77-W88 VanDerWaalsContact CD1-CB 3.48Å; F77-W88 HydrophobicContact CD1-CG 4.31Å; F77-W88 HydrophobicContact CD2-CB 4.31Å; F77-W88 HydrophobicContact CE1-CB 3.6Å; F77-W88 HydrophobicContact CE1-CD2 4.22Å; F77-W88 HydrophobicContact CE1-CE3 4.03Å; F77-W88 HydrophobicContact CE1-CG 4.09Å; F77-W88 HydrophobicContact CE2-CB 4.37Å; F77-W88 HydrophobicContact CG-CB 3.88Å; F77-W88 HydrophobicContact CZ-CB 4.06Å; F77-W88 AromaticContact CZ-CE3 3.9Å; F77-W88 HydrophobicContact CZ-CE3 3.9Å; F77-A90 HydrophobicContact CD2-CB 3.74Å; F77-A90 HydrophobicContact CE2-CB 3.82Å; F77-L104 HydrophobicContact CE2-CD2 4.27Å; F77-L104 HydrophobicContact CE2-CG 4.18Å; F77-L104 HydrophobicContact CZ-CD2 4.16Å
78S91.7Very high84Confident14 Ų1468.6 Ų68.610%0.09839%0.385CS..EExtended strand (participates in β ladder)trans-114.9144.3-170.2155.10000110.9N56 I57 A80N56-S78 PolarHBondContact OD1-OG 2.99Å; I57-S78 WeakPolarHBondContact O-CA 3.37Å; S78-A80 PolarHBondContact O-N 2.97Å; S78-A80 PolarHBondContact OG-N 3.18Å
79L88.3Confident83.9Confident17 Ų1769.7 Ų69.79%0.08939%0.39CS..THydrogen-bonded Turntrans-65.5-26.3172.5-168.663.5000112.9F50 I57 F59 A90 L92 V102F50-L79 HydrophobicContact CD1-CD2 4.31Å; F50-L79 HydrophobicContact CE1-CD2 3.67Å; F50-L79 HydrophobicContact CE2-CD2 4.32Å; F50-L79 HydrophobicContact CZ-CD2 3.7Å; I57-L79 HydrophobicContact CB-CB 4.27Å; I57-L79 HydrophobicContact CB-CD2 4.4Å; I57-L79 HydrophobicContact CD1-CD2 4.18Å; I57-L79 PolarHBondContact O-N 2.92Å; F59-L79 HydrophobicContact CE2-CB 4.21Å; F59-L79 HydrophobicContact CE2-CD1 4.43Å; L79-A90 HydrophobicContact CD1-CB 4.3Å; L79-L92 HydrophobicContact CD1-CB 4.37Å; L79-V102 HydrophobicContact CD1-CB 4.18Å; L79-V102 HydrophobicContact CD1-CG1 3.73Å; L79-V102 HydrophobicContact CD2-CG1 3.85Å; L79-V102 HydrophobicContact CG-CG1 4.48Å
80A67.8Low83.9Confident59 Ų5965.5 Ų65.549%0.48837%0.37SS..THydrogen-bonded Turntrans-97.5-4.3-170.200000114.1S78S78-A80 PolarHBondContact O-N 2.97Å; S78-A80 PolarHBondContact OG-N 3.18Å
81R60.5Low83.9Confident179 Ų17964.5 Ų64.568%0.67535%0.345SS*.  trans-128.5101.9-172.3-70.7-172.5173.3-170.1-0.6112.8H83 S84R81-H83 PolarHBondContact O-N 3.42Å; R81-S84 PolarHBondContact O-N 3.04Å
82H53Low83.9Confident175 Ų17563.5 Ų63.581%0.8134%0.34SS*.THydrogen-bonded Turntrans-64-2.1165.8-68.8-71.2000114.2
83H50.9Low83.9Confident180 Ų18065.9 Ų65.983%0.83334%0.341SS*.THydrogen-bonded Turntrans-120.725.6-179-59-59.1000113.5R81R81-H83 PolarHBondContact O-N 3.42Å
84S57.3Low83.7Confident41 Ų4169.6 Ų69.629%0.28736%0.363SS..  trans-67.2136.6168.3-170.80000109.4R81 S86R81-S84 PolarHBondContact O-N 3.04Å; S84-S86 PolarHBondContact O-N 2.83Å; S84-S86 VanDerWaalsContact O-N 3.16Å
85P71.4Confident83.5Confident135 Ų13569.2 Ų69.288%0.87737%0.367SS*.SBendtrans-69.9-4.4174.830.3-35.6000113.1
86S83.3Confident83.2Confident19 Ų1970.4 Ų70.413%0.13338%0.381CS..  trans-68.6134.1177.21690000111.1V76 S84 W88V76-S86 WeakPolarHBondContact O-CB 3.34Å; S84-S86 PolarHBondContact O-N 2.83Å; S84-S86 VanDerWaalsContact O-N 3.16Å; S86-W88 PolarHBondContact O-N 3.29Å; S86-W88 WeakPolarHBondContact OG-CB 3.5Å; S86-W88 PolarHBondContact OG-N 2.92Å; S86-W88 VanDerWaalsContact OG-N 3.08Å; S86-W88 PolarHBondContact OG-O 2.81Å
87P89.4Confident82.9Confident88 Ų8872.2 Ų72.257%0.57140%0.401SS*.SBendtrans-73.6-15.6172.632.9-36.5000112.4P107P87-P107 HydrophobicContact CB-CB 3.93Å; P87-P107 HydrophobicContact CB-CG 3.89Å; P87-P107 HydrophobicContact CG-CG 4.03Å
88W95.2Very high82.8Confident6 Ų676 Ų762%0.02342%0.424CS..  trans-80137166.1-70.471.3000110.3V61 A75 F77 S86 C105 A106 P107 A110 Y115 F136 L138V61-W88 HydrophobicContact CB-CH2 4.46Å; V61-W88 HydrophobicContact CB-CZ3 4.47Å; V61-W88 HydrophobicContact CG1-CE3 4.4Å; V61-W88 HydrophobicContact CG1-CZ3 4.13Å; V61-W88 HydrophobicContact CG2-CD2 3.82Å; V61-W88 HydrophobicContact CG2-CE3 3.96Å; V61-W88 HydrophobicContact CG2-CG 4.42Å; V61-W88 HydrophobicContact CG2-CH2 4.01Å; V61-W88 HydrophobicContact CG2-CZ2 3.88Å; V61-W88 HydrophobicContact CG2-CZ3 4.04Å; A75-W88 HydrophobicContact CB-CB 4.24Å; A75-W88 HydrophobicContact CB-CD2 4.44Å; A75-W88 HydrophobicContact CB-CG 3.78Å; F77-W88 VanDerWaalsContact CB-O 3.3Å; F77-W88 WeakPolarHBondContact CB-O 3.33Å; F77-W88 HydrophobicContact CD1-CB 3.48Å; F77-W88 VanDerWaalsContact CD1-CB 3.48Å; F77-W88 HydrophobicContact CD1-CG 4.31Å; F77-W88 HydrophobicContact CD2-CB 4.31Å; F77-W88 HydrophobicContact CE1-CB 3.6Å; F77-W88 HydrophobicContact CE1-CD2 4.22Å; F77-W88 HydrophobicContact CE1-CE3 4.03Å; F77-W88 HydrophobicContact CE1-CG 4.09Å; F77-W88 HydrophobicContact CE2-CB 4.37Å; F77-W88 HydrophobicContact CG-CB 3.88Å; F77-W88 HydrophobicContact CZ-CB 4.06Å; F77-W88 AromaticContact CZ-CE3 3.9Å; F77-W88 HydrophobicContact CZ-CE3 3.9Å; S86-W88 PolarHBondContact O-N 3.29Å; S86-W88 WeakPolarHBondContact OG-CB 3.5Å; S86-W88 PolarHBondContact OG-N 2.92Å; S86-W88 VanDerWaalsContact OG-N 3.08Å; S86-W88 PolarHBondContact OG-O 2.81Å; W88-C105 WeakPolarHBondContact CA-O 3.43Å; W88-A106 HydrophobicContact CD2-CB 4.02Å; W88-A106 HydrophobicContact CE3-CB 3.82Å; W88-A106 HydrophobicContact CH2-CB 3.36Å; W88-A106 HydrophobicContact CZ2-CB 3.56Å; W88-A106 HydrophobicContact CZ3-CB 3.49Å; W88-A106 VanDerWaalsContact CZ3-CB 3.49Å; W88-P107 VanDerWaalsContact CD1-CD 3.43Å; W88-A110 HydrophobicContact CZ2-CB 4.15Å; W88-Y115 HydrophobicContact CH2-CD1 4.41Å; W88-Y115 HydrophobicContact CH2-CE1 4.2Å; W88-Y115 HydrophobicContact CZ2-CD1 4.47Å; W88-Y115 AromaticContact CZ2-CE1 3.85Å; W88-Y115 HydrophobicContact CZ2-CE1 3.85Å; W88-F136 HydrophobicContact CH2-CE2 4.27Å; W88-F136 AromaticContact CH2-CZ 3.89Å; W88-F136 HydrophobicContact CH2-CZ 3.89Å; W88-F136 HydrophobicContact CZ3-CZ 4.09Å; W88-L138 HydrophobicContact CH2-CD2 4.01Å; W88-L138 HydrophobicContact CZ2-CD2 4.11Å
89I94.6Very high83Confident89 Ų8977 Ų7746%0.45643%0.431SS..EExtended strand (participates in β ladder)trans-127.2149.1-177.255.8167.5000111.1W91 L104 C105I89-W91 HydrophobicContact CD1-CE3 4.12Å; I89-W91 HydrophobicContact CD1-CH2 4.46Å; I89-W91 HydrophobicContact CD1-CZ3 3.54Å; I89-W91 HydrophobicContact CG1-CE3 4.32Å; I89-W91 HydrophobicContact CG1-CZ3 3.8Å; I89-L104 WeakPolarHBondContact O-CA 3.36Å; I89-C105 HydrophobicContact CD1-CB 4.14Å; I89-C105 HydrophobicContact CG1-CB 3.75Å; I89-C105 PolarHBondContact N-O 2.92Å; I89-C105 VanDerWaalsContact N-O 3.13Å; I89-C105 PolarHBondContact O-N 2.9Å
90A94.7Very high83.3Confident11 Ų1176.2 Ų76.29%0.09143%0.427CS..EExtended strand (participates in β ladder)trans-133.1145.1170.700000109.8F59 F77 L79 S103F59-A90 HydrophobicContact CD2-CB 3.7Å; F59-A90 HydrophobicContact CE2-CB 3.61Å; F77-A90 HydrophobicContact CD2-CB 3.74Å; F77-A90 HydrophobicContact CE2-CB 3.82Å; L79-A90 HydrophobicContact CD1-CB 4.3Å; A90-S103 CarbonylContact C-O 3.58Å; A90-S103 WeakPolarHBondContact CA-O 3.46Å
91W93.9Very high84.7Confident76 Ų7674.8 Ų74.829%0.28841%0.41SS..EExtended strand (participates in β ladder)trans-144.2158.9172.26392.4000111.5A38 I89 E93 V102 S103 C105A38-W91 HydrophobicContact CB-CH2 3.46Å; A38-W91 VanDerWaalsContact CB-CH2 3.46Å; A38-W91 HydrophobicContact CB-CZ2 3.73Å; I89-W91 HydrophobicContact CD1-CE3 4.12Å; I89-W91 HydrophobicContact CD1-CH2 4.46Å; I89-W91 HydrophobicContact CD1-CZ3 3.54Å; I89-W91 HydrophobicContact CG1-CE3 4.32Å; I89-W91 HydrophobicContact CG1-CZ3 3.8Å; W91-E93 PolarHBondContact NE1-OE1 2.97Å; W91-V102 WeakPolarHBondContact O-CA 3.49Å; W91-S103 VanDerWaalsContact CZ2-CB 3.42Å; W91-S103 PolarHBondContact N-O 3.3Å; W91-S103 PolarHBondContact O-N 2.8Å; W91-C105 HydrophobicContact CH2-CB 4.01Å; W91-C105 HydrophobicContact CZ3-CB 3.87Å
92L94.2Very high86.4Confident65 Ų6566.2 Ų66.234%0.3438%0.378SS..EExtended strand (participates in β ladder)trans-80.1127.9179.6-179.966.6000109.6P52 L79 N95 T100P52-L92 HydrophobicContact CG-CD2 4.49Å; L79-L92 HydrophobicContact CD1-CB 4.37Å; L92-N95 HydrophobicContact CD1-CB 4.13Å; L92-N95 HydrophobicContact CD2-CB 4.14Å; L92-T100 HydrophobicContact CD1-CG2 3.15Å
93E94.4Very high88.5Confident87 Ų8758 Ų5841%0.40734%0.34SS..EExtended strand (participates in β ladder)trans-97.5-57.1174.5-68.9-71.4177.400110.5W91 E101 S103W91-E93 PolarHBondContact NE1-OE1 2.97Å; E93-E101 HydrophobicContact CB-CB 4.23Å; E93-E101 HydrophobicContact CB-CG 4.15Å; E93-E101 PolarHBondContact N-O 2.75Å; E93-S103 VanDerWaalsContact CD-OG 3.27Å; E93-S103 WeakPolarHBondContact CG-OG 3.42Å; E93-S103 WeakPolarHBondContact OE1-CB 3.41Å; E93-S103 PolarHBondContact OE1-OG 3.14Å
94T93.6Very high90.8Very high78 Ų7849.4 Ų49.448%0.47930%0.3SS..EExtended strand (participates in β ladder)trans-137.3142.1178.264.40000110.5T100 E101T94-T100 WeakPolarHBondContact O-CA 3.36Å; T94-E101 PolarHBondContact N-O 3.01Å; T94-E101 PolarHBondContact O-N 2.83Å; T94-E101 WeakPolarHBondContact OG1-CB 3.34Å; T94-E101 PolarHBondContact OG1-OE2 3.17Å
95N93.3Very high92.7Very high72 Ų7248.3 Ų48.339%0.38529%0.293SS..EExtended strand (participates in β ladder)trans-125.8113.9177.7-161.130000110.1F50 L92 T100F50-N95 PolarHBondContact O-ND2 3.22Å; F50-N95 PolarHBondContact O-OD1 3.47Å; L92-N95 HydrophobicContact CD1-CB 4.13Å; L92-N95 HydrophobicContact CD2-CB 4.14Å; N95-T100 PolarHBondContact OD1-OG1 2.94Å
96G90.8Very high93.9Very high33 Ų3341.9 Ų41.934%0.3425%0.251SS..  trans-106.3179.8179.400000112.8T98 S99G96-T98 VanDerWaalsContact C-N 3.29Å; G96-T98 PolarHBondContact O-N 2.82Å; G96-S99 VanDerWaalsContact CA-O 3.29Å; G96-S99 WeakPolarHBondContact CA-O 3.06Å; G96-S99 PolarHBondContact N-O 2.75Å
97A89.3Confident94.6Very high89 Ų8941.7 Ų41.774%0.73625%0.249SC*.SBendtrans-65.9-29.7-178.700000113.5G49G49-A97 VanDerWaalsContact CA-O 3.22Å; G49-A97 WeakPolarHBondContact CA-O 2.86Å; G49-A97 PolarHBondContact N-O 2.84Å
98T91.1Very high95Very high83 Ų8339.1 Ų39.151%0.50923%0.232SC..SBendtrans-137.82.9-176.754.20000113.4F45 G96F45-T98 PolarHBondContact N-O 2.94Å; G96-T98 VanDerWaalsContact C-N 3.29Å; G96-T98 PolarHBondContact O-N 2.82Å
99S95.4Very high95.1Very high35 Ų3543.3 Ų43.325%0.24526%0.259CS..EExtended strand (participates in β ladder)trans-146.7150.9-178.862.90000111.5L43 G96L43-S99 CarbonylContact O-C 3.49Å; L43-S99 WeakPolarHBondContact O-CA 3.18Å; G96-S99 VanDerWaalsContact CA-O 3.29Å; G96-S99 WeakPolarHBondContact CA-O 3.06Å; G96-S99 PolarHBondContact N-O 2.75Å
100T95.6Very high95.3Very high0 Ų039.4 Ų39.40%024%0.24CC..EExtended strand (participates in β ladder)trans-136.6126.1178.2-58.50000109.4T42 L43 F45 F50 L92 T94 N95 V102T42-T100 WeakPolarHBondContact CA-O 3.33Å; L43-T100 PolarHBondContact N-O 3.44Å; L43-T100 PolarHBondContact O-N 2.87Å; F45-T100 WeakPolarHBondContact CE2-OG1 3.34Å; F50-T100 HydrophobicContact CB-CG2 4.46Å; F50-T100 VanDerWaalsContact CB-OG1 3.28Å; F50-T100 WeakPolarHBondContact CB-OG1 3.43Å; F50-T100 HydrophobicContact CD1-CG2 4.26Å; L92-T100 HydrophobicContact CD1-CG2 3.15Å; T94-T100 WeakPolarHBondContact O-CA 3.36Å; N95-T100 PolarHBondContact OD1-OG1 2.94Å; T100-V102 HydrophobicContact CG2-CG1 3.97Å
101E96.9Very high95.5Very high29 Ų2939.2 Ų39.214%0.13624%0.238CC..EExtended strand (participates in β ladder)trans-92.7131.8170.5-168.6177.6-162.700109.2Q13 R16 L41 E93 T94Q13-E101 PolarHBondContact NE2-OE1 3.25Å; Q13-E101 PolarHBondContact OE1-OE1 2.94Å; R16-E101 IonicContact NH1-OE1 3.42Å; R16-E101 PolarHBondContact NH1-OE1 2.9Å; L41-E101 WeakPolarHBondContact O-CA 3.35Å; E93-E101 HydrophobicContact CB-CB 4.23Å; E93-E101 HydrophobicContact CB-CG 4.15Å; E93-E101 PolarHBondContact N-O 2.75Å; T94-E101 PolarHBondContact N-O 3.01Å; T94-E101 PolarHBondContact O-N 2.83Å; T94-E101 WeakPolarHBondContact OG1-CB 3.34Å; T94-E101 PolarHBondContact OG1-OE2 3.17Å
102V96.7Very high95.8Very high0 Ų035.6 Ų35.60%022%0.224CC..EExtended strand (participates in β ladder)trans-128.5149.7179.7-59.90000109.3N40 L41 F59 L79 W91 T100 L104N40-V102 CarbonylContact C-O 3.53Å; N40-V102 WeakPolarHBondContact CA-O 3.36Å; L41-V102 HydrophobicContact CD1-CG2 3.39Å; L41-V102 HydrophobicContact CD2-CG2 4.4Å; L41-V102 HydrophobicContact CG-CG2 3.57Å; L41-V102 PolarHBondContact N-O 2.8Å; L41-V102 PolarHBondContact O-N 2.89Å; F59-V102 HydrophobicContact CE1-CG2 4.34Å; F59-V102 HydrophobicContact CZ-CB 4.45Å; F59-V102 HydrophobicContact CZ-CG2 3.9Å; L79-V102 HydrophobicContact CD1-CB 4.18Å; L79-V102 HydrophobicContact CD1-CG1 3.73Å; L79-V102 HydrophobicContact CD2-CG1 3.85Å; L79-V102 HydrophobicContact CG-CG1 4.48Å; W91-V102 WeakPolarHBondContact O-CA 3.49Å; T100-V102 HydrophobicContact CG2-CG1 3.97Å; V102-L104 HydrophobicContact CB-CD1 4.42Å; V102-L104 HydrophobicContact CG2-CD1 3.69Å
103S97.3Very high96Very high1 Ų132.5 Ų32.51%0.00721%0.209CC..EExtended strand (participates in β ladder)trans-108.4136.8171.2-77.60000109.6F39 N40 A90 W91 E93F39-S103 WeakPolarHBondContact O-CA 3.24Å; N40-S103 PolarHBondContact ND2-OG 3.04Å; A90-S103 CarbonylContact C-O 3.58Å; A90-S103 WeakPolarHBondContact CA-O 3.46Å; W91-S103 VanDerWaalsContact CZ2-CB 3.42Å; W91-S103 PolarHBondContact N-O 3.3Å; W91-S103 PolarHBondContact O-N 2.8Å; E93-S103 VanDerWaalsContact CD-OG 3.27Å; E93-S103 WeakPolarHBondContact CG-OG 3.42Å; E93-S103 WeakPolarHBondContact OE1-CB 3.41Å; E93-S103 PolarHBondContact OE1-OG 3.14Å
104L97.5Very high96.2Very high0 Ų032.6 Ų32.60%021%0.205CC..EExtended strand (participates in β ladder)trans-118.4140.8175.9-71.770.2000108.3A38 F39 L41 F59 F77 I89 V102 L117A38-L104 CarbonylContact C-O 3.47Å; A38-L104 VanDerWaalsContact CA-O 3.26Å; A38-L104 WeakPolarHBondContact CA-O 3.37Å; F39-L104 HydrophobicContact CD1-CB 4.45Å; F39-L104 WeakPolarHBondContact CD1-O 3.35Å; F39-L104 HydrophobicContact CE1-CB 3.92Å; F39-L104 HydrophobicContact CE2-CB 4.05Å; F39-L104 HydrophobicContact CE2-CD2 4.23Å; F39-L104 HydrophobicContact CZ-CB 3.71Å; F39-L104 HydrophobicContact CZ-CD2 4.06Å; F39-L104 HydrophobicContact CZ-CG 4.49Å; F39-L104 PolarHBondContact N-O 3.14Å; F39-L104 PolarHBondContact O-N 2.86Å; L41-L104 HydrophobicContact CD2-CD1 3.55Å; L41-L104 HydrophobicContact CD2-CD2 3.98Å; L41-L104 HydrophobicContact CD2-CG 4.45Å; L41-L104 HydrophobicContact CG-CD1 3.91Å; F59-L104 HydrophobicContact CD1-CD2 3.89Å; F59-L104 HydrophobicContact CD1-CG 4.48Å; F59-L104 HydrophobicContact CE1-CD1 4.16Å; F59-L104 HydrophobicContact CE1-CD2 4.22Å; F59-L104 HydrophobicContact CE1-CG 4.5Å; F59-L104 HydrophobicContact CG-CD2 4.37Å; F59-L104 HydrophobicContact CZ-CD1 4.34Å; F77-L104 HydrophobicContact CE2-CD2 4.27Å; F77-L104 HydrophobicContact CE2-CG 4.18Å; F77-L104 HydrophobicContact CZ-CD2 4.16Å; I89-L104 WeakPolarHBondContact O-CA 3.36Å; V102-L104 HydrophobicContact CB-CD1 4.42Å; V102-L104 HydrophobicContact CG2-CD1 3.69Å; L104-L117 HydrophobicContact CD2-CD1 3.93Å; L104-L117 HydrophobicContact CD2-CD2 4.27Å
105C97.6Very high96.4Very high18 Ų1829 Ų2912%0.12218%0.183CC..EExtended strand (participates in β ladder)trans-134.5122.7174.5-170.70000110.7A38 W88 I89 W91A38-C105 HydrophobicContact CB-CB 4.27Å; W88-C105 WeakPolarHBondContact CA-O 3.43Å; I89-C105 HydrophobicContact CD1-CB 4.14Å; I89-C105 HydrophobicContact CG1-CB 3.75Å; I89-C105 PolarHBondContact N-O 2.92Å; I89-C105 VanDerWaalsContact N-O 3.13Å; I89-C105 PolarHBondContact O-N 2.9Å; W91-C105 HydrophobicContact CH2-CB 4.01Å; W91-C105 HydrophobicContact CZ3-CB 3.87Å
106A97.9Very high96.6Very high1 Ų127.4 Ų27.41%0.00817%0.174CC..  trans-77.4144.7169.900000109.8R35 G36 W88 A110 L138R35-A106 HydrophobicContact CB-CB 4.49Å; G36-A106 WeakPolarHBondContact CA-O 3.33Å; G36-A106 PolarHBondContact N-O 3.39Å; W88-A106 HydrophobicContact CD2-CB 4.02Å; W88-A106 HydrophobicContact CE3-CB 3.82Å; W88-A106 HydrophobicContact CH2-CB 3.36Å; W88-A106 HydrophobicContact CZ2-CB 3.56Å; W88-A106 HydrophobicContact CZ3-CB 3.49Å; W88-A106 VanDerWaalsContact CZ3-CB 3.49Å; A106-A110 HydrophobicContact CB-CB 4.11Å; A106-L138 HydrophobicContact CB-CD1 4.14Å; A106-L138 HydrophobicContact CB-CD2 3.77Å
107P97.7Very high97Very high15 Ų1525.9 Ų25.910%0.09716%0.158CC..  trans-63.6152.517428.3-35.2000111.2P87 W88 T109 A110P87-P107 HydrophobicContact CB-CB 3.93Å; P87-P107 HydrophobicContact CB-CG 3.89Å; P87-P107 HydrophobicContact CG-CG 4.03Å; W88-P107 VanDerWaalsContact CD1-CD 3.43Å; P107-T109 PolarHBondContact O-N 2.87Å; P107-A110 HydrophobicContact CG-CB 4.05Å; P107-A110 VanDerWaalsContact O-CB 3.31Å; P107-A110 WeakPolarHBondContact O-CB 3.3Å; P107-A110 PolarHBondContact O-N 2.95Å
108P98.1Very high97.4Very high33 Ų3324.2 Ų24.221%0.21413%0.134CC..THydrogen-bonded Turntrans-60.5-8.5176.7-20.930.3000114.9R35 E146 D147R35-P108 WeakPolarHBondContact CD-O 3.44Å; R35-P108 PolarHBondContact NE-O 3.22Å; R35-P108 PolarHBondContact NH1-O 2.98Å; R35-P108 PolarHBondContact NH2-O 3.4Å; P108-E146 HydrophobicContact CB-CB 3.96Å; P108-E146 HydrophobicContact CG-CB 3.59Å; P108-D147 HydrophobicContact CB-CB 4.42Å
109T97.6Very high97.7Very high95 Ų9520.2 Ų20.258%0.58311%0.11SC*.THydrogen-bonded Turntrans-105.3-0.1177.954.70000113.6P107P107-T109 PolarHBondContact O-N 2.87Å
110A98.6Very high97.6Very high7 Ų721.5 Ų21.56%0.05811%0.112CC..PPolyproline II helixtrans-55.8144.5179.500000111.5R35 W88 A106 P107 L138R35-A110 HydrophobicContact CB-CB 4.37Å; R35-A110 WeakPolarHBondContact CD-O 3.27Å; R35-A110 PolarHBondContact NH1-O 2.8Å; W88-A110 HydrophobicContact CZ2-CB 4.15Å; A106-A110 HydrophobicContact CB-CB 4.11Å; P107-A110 HydrophobicContact CG-CB 4.05Å; P107-A110 VanDerWaalsContact O-CB 3.31Å; P107-A110 WeakPolarHBondContact O-CB 3.3Å; P107-A110 PolarHBondContact O-N 2.95Å; A110-L138 HydrophobicContact CB-CD2 3.61Å
111A98.6Very high97.4Very high6 Ų621.5 Ų21.55%0.0511%0.112CC..PPolyproline II helixtrans-60.6138.6174.700000110.8T63 Y115 C212 R215T63-A111 HydrophobicContact CG2-CB 4.39Å; A111-Y115 VanDerWaalsContact O-CE2 3.24Å; A111-Y115 WeakPolarHBondContact O-CE2 3.41Å; A111-Y115 PolarHBondContact O-OH 2.87Å; A111-C212 VanDerWaalsContact CB-O 3.31Å; A111-C212 WeakPolarHBondContact CB-O 3.49Å; A111-R215 HydrophobicContact CB-CB 4.25Å
112V98.8Very high97Very high0 Ų023.6 Ų23.60%012%0.124CC..PPolyproline II helixtrans-83.7144.3173.4-57.60000110.3L138 F140 R215 V221V112-L138 CarbonylContact C-O 3.59Å; V112-L138 VanDerWaalsContact CA-O 3.25Å; V112-L138 WeakPolarHBondContact CA-O 3.43Å; V112-L138 VanDerWaalsContact CB-O 3.31Å; V112-L138 WeakPolarHBondContact CB-O 3.46Å; V112-F140 HydrophobicContact CB-CD2 4.45Å; V112-F140 HydrophobicContact CB-CE2 4.28Å; V112-F140 HydrophobicContact CG1-CD1 4.14Å; V112-F140 HydrophobicContact CG1-CD2 3.65Å; V112-F140 HydrophobicContact CG1-CE1 4.17Å; V112-F140 HydrophobicContact CG1-CE2 3.69Å; V112-F140 HydrophobicContact CG1-CG 3.85Å; V112-F140 HydrophobicContact CG1-CZ 3.95Å; V112-F140 HydrophobicContact CG2-CD2 4.18Å; V112-F140 HydrophobicContact CG2-CE2 3.61Å; V112-F140 HydrophobicContact CG2-CZ 4.12Å; V112-R215 HydrophobicContact CG2-CB 4.3Å; V112-R215 PolarHBondContact N-O 2.75Å; V112-V221 HydrophobicContact CG2-CG2 4.43Å
113G98.4Very high96.4Very high1 Ų124 Ų241%0.0113%0.127CC..EExtended strand (participates in β ladder)trans151.3-170.1-178.800000114.3I137 L138G113-I137 WeakPolarHBondContact O-CA 3.48Å; G113-L138 PolarHBondContact N-O 2.99Å; G113-L138 PolarHBondContact O-N 2.76Å
114R98.6Very high95.2Very high89 Ų8931.1 Ų31.134%0.33616%0.158SC..EExtended strand (participates in β ladder)trans-79.6130.4172.9-60.9-170.2177.586-0.6109.8T63 I137 D192 L195T63-R114 WeakPolarHBondContact CB-O 3.47Å; T63-R114 PolarHBondContact OG1-O 2.96Å; R114-I137 HydrophobicContact CG-CG1 4.18Å; R114-D192 IonicContact CZ-OD1 3.49Å; R114-D192 IonicContact NE-OD1 2.74Å; R114-D192 VanDerWaalsContact NH2-CA 3.28Å; R114-D192 PolarHBondContact NH2-O 3.07Å; R114-D192 IonicContact NH2-OD1 3.56Å; R114-D192 PolarHBondContact NH2-OD1 3.18Å; R114-L195 HydrophobicContact CG-CD1 3.81Å
115Y98.7Very high93.7Very high3 Ų337.4 Ų37.41%0.01219%0.187CC..EExtended strand (participates in β ladder)trans-117.1140.6177.4-82.9-97.3000111.1V61 E62 T63 W88 A111 E135 F136 L138V61-Y115 HydrophobicContact CB-CD1 4.06Å; V61-Y115 HydrophobicContact CG2-CD1 4.46Å; E62-Y115 CarbonylContact O-C 3.56Å; E62-Y115 VanDerWaalsContact O-CA 3.28Å; E62-Y115 WeakPolarHBondContact O-CA 3.34Å; T63-Y115 HydrophobicContact CG2-CD1 4.28Å; T63-Y115 HydrophobicContact CG2-CE1 3.56Å; T63-Y115 HydrophobicContact CG2-CE2 4Å; T63-Y115 WeakPolarHBondContact CG2-OH 3.27Å; W88-Y115 HydrophobicContact CH2-CD1 4.41Å; W88-Y115 HydrophobicContact CH2-CE1 4.2Å; W88-Y115 HydrophobicContact CZ2-CD1 4.47Å; W88-Y115 AromaticContact CZ2-CE1 3.85Å; W88-Y115 HydrophobicContact CZ2-CE1 3.85Å; A111-Y115 VanDerWaalsContact O-CE2 3.24Å; A111-Y115 WeakPolarHBondContact O-CE2 3.41Å; A111-Y115 PolarHBondContact O-OH 2.87Å; Y115-E135 CarbonylContact O-C 3.55Å; Y115-E135 WeakPolarHBondContact O-CA 3.34Å; Y115-F136 VanDerWaalsContact CB-CE1 3.44Å; Y115-F136 HydrophobicContact CD1-CZ 4.2Å; Y115-F136 HydrophobicContact CD2-CE2 4.19Å; Y115-F136 HydrophobicContact CD2-CZ 4.38Å; Y115-F136 HydrophobicContact CG-CE1 4.29Å; Y115-F136 HydrophobicContact CG-CE2 4.01Å; Y115-F136 AromaticContact CG-CZ 3.75Å; Y115-F136 HydrophobicContact CG-CZ 3.75Å; Y115-F136 PolarHBondContact N-O 2.82Å; Y115-F136 PolarHBondContact O-N 2.86Å; Y115-L138 HydrophobicContact CD2-CB 3.78Å; Y115-L138 HydrophobicContact CE2-CB 3.72Å; Y115-L138 HydrophobicContact CE2-CD2 3.86Å; Y115-L138 HydrophobicContact CE2-CG 4.46Å
116L98.6Very high92.3Very high37 Ų3738 Ų3819%0.19420%0.197CC..EExtended strand (participates in β ladder)trans-95.6126167-176.358.8000109.4V61 E62 K118 Q132 E135V61-L116 WeakPolarHBondContact CA-O 3.45Å; E62-L116 PolarHBondContact N-O 3.33Å; E62-L116 VanDerWaalsContact N-O 3.09Å; E62-L116 PolarHBondContact O-N 2.9Å; L116-K118 HydrophobicContact CG-CG 4.36Å; L116-Q132 HydrophobicContact CD1-CG 3.77Å; L116-E135 HydrophobicContact CD1-CG 3.99Å
117L98.4Very high91.1Very high1 Ų142.7 Ų42.71%0.00523%0.229CC..EExtended strand (participates in β ladder)trans-103.4125.6176.9-179.363.2000110.8L12 L41 F59 V61 L104 L133 G134 F136L12-L117 HydrophobicContact CD2-CD2 4.28Å; L41-L117 HydrophobicContact CD2-CD2 3.59Å; F59-L117 HydrophobicContact CD1-CD1 4.23Å; V61-L117 HydrophobicContact CG1-CD1 3.56Å; L104-L117 HydrophobicContact CD2-CD1 3.93Å; L104-L117 HydrophobicContact CD2-CD2 4.27Å; L117-L133 HydrophobicContact CB-CB 4.47Å; L117-L133 HydrophobicContact CD2-CB 4.19Å; L117-L133 HydrophobicContact CD2-CD1 4.08Å; L117-L133 HydrophobicContact CG-CB 4.11Å; L117-L133 HydrophobicContact CG-CD1 4.18Å; L117-L133 HydrophobicContact CG-CG 4.46Å; L117-L133 PolarHBondContact O-N 3.02Å; L117-G134 PolarHBondContact N-O 3.39Å; L117-G134 PolarHBondContact O-N 3.45Å; L117-F136 HydrophobicContact CB-CD1 4.23Å; L117-F136 HydrophobicContact CB-CE1 4.11Å
118K97.8Very high90.3Very high54 Ų5446.4 Ų46.424%0.23525%0.251CS..EExtended strand (participates in β ladder)trans-128.9160175.9-58.6168.8-177.5165.10110.2F59 V60 E62 L116 Y131F59-K118 WeakPolarHBondContact CA-O 3.47Å; V60-K118 HydrophobicContact CB-CB 4.25Å; V60-K118 PolarHBondContact N-O 3.08Å; V60-K118 PolarHBondContact O-N 2.64Å; E62-K118 IonicContact OE2-NZ 2.71Å; E62-K118 PolarHBondContact OE2-NZ 3.09Å; L116-K118 HydrophobicContact CG-CG 4.36Å; K118-Y131 CarbonylContact C-O 3.59Å; K118-Y131 VanDerWaalsContact CA-O 3.25Å; K118-Y131 WeakPolarHBondContact CA-O 3.39Å
119I96.1Very high89.9Confident0 Ų046.6 Ų46.60%025%0.252CS..EExtended strand (participates in β ladder)trans-131.4147.5167.257.1173.4000111.5V7 L43 I57 I58 F59 I121 A130 Y131 L133V7-I119 HydrophobicContact CG2-CD1 3.83Å; L43-I119 HydrophobicContact CD1-CD1 4.14Å; L43-I119 HydrophobicContact CD2-CD1 4.24Å; I57-I119 HydrophobicContact CG2-CB 4.2Å; I57-I119 HydrophobicContact CG2-CD1 4.46Å; I57-I119 HydrophobicContact CG2-CG2 4.02Å; I58-I119 CarbonylContact O-C 3.57Å; I58-I119 VanDerWaalsContact O-CA 3.23Å; I58-I119 WeakPolarHBondContact O-CA 3.41Å; F59-I119 HydrophobicContact CD1-CG2 3.3Å; F59-I119 HydrophobicContact CE1-CG2 3.51Å; F59-I119 HydrophobicContact CG-CG2 4.07Å; F59-I119 HydrophobicContact CZ-CG2 4.4Å; I119-I121 HydrophobicContact CD1-CD1 4.1Å; I119-I121 HydrophobicContact CD1-CG1 4.22Å; I119-A130 CarbonylContact O-C 3.51Å; I119-A130 VanDerWaalsContact O-CA 3.32Å; I119-A130 WeakPolarHBondContact O-CA 3.31Å; I119-Y131 HydrophobicContact CD1-CD2 4.3Å; I119-Y131 HydrophobicContact CG1-CD2 4.14Å; I119-Y131 PolarHBondContact N-O 2.86Å; I119-Y131 PolarHBondContact O-N 2.83Å; I119-L133 HydrophobicContact CB-CD1 4.45Å; I119-L133 HydrophobicContact CD1-CD1 4.1Å; I119-L133 HydrophobicContact CD1-CD2 3.81Å; I119-L133 HydrophobicContact CD1-CG 4.34Å; I119-L133 HydrophobicContact CG1-CD1 4.1Å; I119-L133 HydrophobicContact CG1-CD2 3.75Å; I119-L133 HydrophobicContact CG1-CG 4.02Å; I119-L133 HydrophobicContact CG2-CD1 3.62Å; I119-L133 HydrophobicContact CG2-CG 4.23Å
120H94.3Very high89.6Confident61 Ų6145.3 Ų45.328%0.28225%0.251SS..EExtended strand (participates in β ladder)trans-111.5131.8162.5-59.6-69.7000108.7I58 V60 V128 T129 A130I58-H120 HydrophobicContact CB-CB 4.24Å; I58-H120 PolarHBondContact N-O 2.94Å; I58-H120 PolarHBondContact O-N 2.62Å; V60-H120 VanDerWaalsContact CG2-CD2 3.47Å; V60-H120 WeakPolarHBondContact CG2-CD2 3.29Å; H120-V128 HydrophobicContact CB-CG1 4.25Å; H120-T129 CarbonylContact C-O 3.57Å; H120-T129 VanDerWaalsContact CA-O 3.28Å; H120-T129 WeakPolarHBondContact CA-O 3.27Å; H120-A130 WeakPolarHBondContact ND1-CB 3.33Å
121I91.7Very high89.5Confident0 Ų047.4 Ų47.40%026%0.258CS..EExtended strand (participates in β ladder)trans-111.6117.6177.1-56.6-174.7000108.2L5 V7 F45 I57 I119 V128 T129 Y131L5-I121 HydrophobicContact CB-CG2 3.96Å; L5-I121 HydrophobicContact CD2-CD1 4.34Å; L5-I121 HydrophobicContact CD2-CG2 4.03Å; L5-I121 HydrophobicContact CG-CD1 4.45Å; L5-I121 HydrophobicContact CG-CG2 4.37Å; V7-I121 HydrophobicContact CG2-CD1 3.52Å; F45-I121 HydrophobicContact CE1-CD1 4.33Å; I57-I121 HydrophobicContact CG1-CG1 4.35Å; I119-I121 HydrophobicContact CD1-CD1 4.1Å; I119-I121 HydrophobicContact CD1-CG1 4.22Å; I121-V128 WeakPolarHBondContact O-CA 3.39Å; I121-T129 PolarHBondContact N-O 2.89Å; I121-T129 PolarHBondContact O-N 2.8Å; I121-T129 VanDerWaalsContact O-N 3.07Å; I121-Y131 HydrophobicContact CD1-CD2 4.28Å; I121-Y131 HydrophobicContact CD1-CE2 3.93Å; I121-Y131 HydrophobicContact CG1-CE2 4.32Å
122D88.6Confident89.4Confident74 Ų7453.3 Ų53.340%0.39628%0.284SS..EExtended strand (participates in β ladder)trans-104.1109.3172.8-177.912.5000108.7D55 N56 V128D55-D122 CarbonylContact C-O 3.54Å; D55-D122 WeakPolarHBondContact CA-O 3.46Å; N56-D122 HydrophobicContact CB-CB 4.34Å; N56-D122 PolarHBondContact N-O 2.96Å; N56-D122 PolarHBondContact O-N 2.87Å; D122-V128 HydrophobicContact CB-CG2 4.41Å
123S84.8Confident89.2Confident7 Ų754.4 Ų54.45%0.04929%0.29CS..EExtended strand (participates in β ladder)trans-106.6137.2178.9-71.90000109.5L5 D55 Q125 G126L5-S123 PolarHBondContact N-OG 2.74Å; D55-S123 WeakPolarHBondContact OD1-CB 3.33Å; D55-S123 PolarHBondContact OD1-OG 2.91Å; S123-Q125 PolarHBondContact O-N 3.26Å; S123-G126 PolarHBondContact O-N 2.89Å
124F71.1Confident89.1Confident151 Ų15155.2 Ų55.266%0.66230%0.299SS*.THydrogen-bonded Turntrans-46.1-23.6-173.9-175.5-108.3000116.6L54L54-F124 HydrophobicContact CD2-CB 4.17Å; L54-F124 HydrophobicContact CD2-CD1 4.26Å; L54-F124 HydrophobicContact CD2-CG 4.18Å; L54-F124 WeakPolarHBondContact O-CB 3.18Å; L54-F124 PolarHBondContact O-N 2.86Å
125Q66.8Low89.1Confident132 Ų13256.9 Ų56.962%0.61731%0.31SS*.THydrogen-bonded Turntrans-136.315.6178.2-68.8-179.9-10.600113.7S123S123-Q125 PolarHBondContact O-N 3.26Å
126G66.6Low89.1Confident31 Ų3157 Ų5732%0.3231%0.311SS..SBendtrans-114.3162.3-177.700000113.1S123S123-G126 PolarHBondContact O-N 2.89Å
127S73.8Confident89.1Confident100 Ų10056 Ų5670%0.69931%0.305SS*.  trans-67.7142.9165.254.40000110T129S127-T129 PolarHBondContact O-N 3.37Å
128V81.3Confident89.1Confident92 Ų9256 Ų5656%0.55831%0.305SS*.  trans-57.4122.9170.3178.70000108.9H120 I121 D122H120-V128 HydrophobicContact CB-CG1 4.25Å; I121-V128 WeakPolarHBondContact O-CA 3.39Å; D122-V128 HydrophobicContact CB-CG2 4.41Å
129T88.8Confident89.1Confident38 Ų3853.4 Ų53.423%0.23329%0.294CS..EExtended strand (participates in β ladder)trans-107.3147.2175.752.30000110.1H120 I121 S127 Y131H120-T129 CarbonylContact C-O 3.57Å; H120-T129 VanDerWaalsContact CA-O 3.28Å; H120-T129 WeakPolarHBondContact CA-O 3.27Å; I121-T129 PolarHBondContact N-O 2.89Å; I121-T129 PolarHBondContact O-N 2.8Å; I121-T129 VanDerWaalsContact O-N 3.07Å; S127-T129 PolarHBondContact O-N 3.37Å; T129-Y131 VanDerWaalsContact OG1-CE2 3.28Å; T129-Y131 WeakPolarHBondContact OG1-CE2 3.32Å; T129-Y131 PolarHBondContact OG1-OH 3.14Å
130A92.4Very high89.3Confident67 Ų6753.4 Ų53.455%0.55429%0.294SS*.EExtended strand (participates in β ladder)trans-125134.7-178.900000110I119 H120I119-A130 CarbonylContact O-C 3.51Å; I119-A130 VanDerWaalsContact O-CA 3.32Å; I119-A130 WeakPolarHBondContact O-CA 3.31Å; H120-A130 WeakPolarHBondContact ND1-CB 3.33Å
131Y95.3Very high89.5Confident52 Ų5250.6 Ų50.620%0.20428%0.281CS..EExtended strand (participates in β ladder)trans-131.9137.2179.3-53.9-90.8000109.9E6 V7 K118 I119 I121 T129E6-Y131 WeakPolarHBondContact CG-OH 3.42Å; V7-Y131 HydrophobicContact CB-CD1 4.04Å; V7-Y131 HydrophobicContact CB-CD2 4.19Å; V7-Y131 HydrophobicContact CB-CE1 4.05Å; V7-Y131 HydrophobicContact CB-CE2 4.21Å; V7-Y131 HydrophobicContact CB-CG 4.12Å; V7-Y131 HydrophobicContact CG2-CD2 3.77Å; V7-Y131 HydrophobicContact CG2-CE2 3.8Å; V7-Y131 HydrophobicContact CG2-CG 4.15Å; K118-Y131 CarbonylContact C-O 3.59Å; K118-Y131 VanDerWaalsContact CA-O 3.25Å; K118-Y131 WeakPolarHBondContact CA-O 3.39Å; I119-Y131 HydrophobicContact CD1-CD2 4.3Å; I119-Y131 HydrophobicContact CG1-CD2 4.14Å; I119-Y131 PolarHBondContact N-O 2.86Å; I119-Y131 PolarHBondContact O-N 2.83Å; I121-Y131 HydrophobicContact CD1-CD2 4.28Å; I121-Y131 HydrophobicContact CD1-CE2 3.93Å; I121-Y131 HydrophobicContact CG1-CE2 4.32Å; T129-Y131 VanDerWaalsContact OG1-CE2 3.28Å; T129-Y131 WeakPolarHBondContact OG1-CE2 3.32Å; T129-Y131 PolarHBondContact OG1-OH 3.14Å
132Q96.1Very high89.8Confident130 Ų13050.6 Ų50.661%0.60728%0.281SS*.EExtended strand (participates in β ladder)trans-88.9117.5165.7179.2172.5-39.900107.9L116L116-Q132 HydrophobicContact CD1-CG 3.77Å
133L96.2Very high90.3Very high22 Ų2248.8 Ų48.812%0.11527%0.269CS..EExtended strand (participates in β ladder)trans-87.5-33-172.9-61.5-164.2000112.7T10 L43 L117 I119T10-L133 HydrophobicContact CG2-CB 4.22Å; T10-L133 HydrophobicContact CG2-CD1 4.26Å; T10-L133 HydrophobicContact CG2-CD2 4.48Å; T10-L133 WeakPolarHBondContact OG1-CD2 3.35Å; L43-L133 HydrophobicContact CD2-CD1 3.84Å; L43-L133 HydrophobicContact CD2-CD2 4.36Å; L117-L133 HydrophobicContact CB-CB 4.47Å; L117-L133 HydrophobicContact CD2-CB 4.19Å; L117-L133 HydrophobicContact CD2-CD1 4.08Å; L117-L133 HydrophobicContact CG-CB 4.11Å; L117-L133 HydrophobicContact CG-CD1 4.18Å; L117-L133 HydrophobicContact CG-CG 4.46Å; L117-L133 PolarHBondContact O-N 3.02Å; I119-L133 HydrophobicContact CB-CD1 4.45Å; I119-L133 HydrophobicContact CD1-CD1 4.1Å; I119-L133 HydrophobicContact CD1-CD2 3.81Å; I119-L133 HydrophobicContact CD1-CG 4.34Å; I119-L133 HydrophobicContact CG1-CD1 4.1Å; I119-L133 HydrophobicContact CG1-CD2 3.75Å; I119-L133 HydrophobicContact CG1-CG 4.02Å; I119-L133 HydrophobicContact CG2-CD1 3.62Å; I119-L133 HydrophobicContact CG2-CG 4.23Å
134G96.1Very high91Very high19 Ų1948.8 Ų48.820%0.19627%0.269CS..EExtended strand (participates in β ladder)trans152.1-168.7-179.200000112.3L117L117-G134 PolarHBondContact N-O 3.39Å; L117-G134 PolarHBondContact O-N 3.45Å
135E97.1Very high92.3Very high123 Ų12345.3 Ų45.358%0.57526%0.261SS*.EExtended strand (participates in β ladder)trans-118152.4177.4-64.6-178.1170.900110.6Y115 L116Y115-E135 CarbonylContact O-C 3.55Å; Y115-E135 WeakPolarHBondContact O-CA 3.34Å; L116-E135 HydrophobicContact CD1-CG 3.99Å
136F98.6Very high93.8Very high6 Ų645.1 Ų45.13%0.02626%0.261CS..EExtended strand (participates in β ladder)trans-144.2159.8171.568.2-85.2000110.5L31 V33 F39 V61 W88 Y115 L117 L138L31-F136 HydrophobicContact CB-CB 3.91Å; L31-F136 HydrophobicContact CD2-CB 3.73Å; L31-F136 HydrophobicContact CD2-CG 4.35Å; L31-F136 HydrophobicContact CG-CB 3.81Å; L31-F136 VanDerWaalsContact O-CA 3.3Å; L31-F136 WeakPolarHBondContact O-CA 3.41Å; L31-F136 WeakPolarHBondContact O-CB 3.46Å; V33-F136 HydrophobicContact CG2-CD2 3.72Å; V33-F136 HydrophobicContact CG2-CE2 4.16Å; F39-F136 HydrophobicContact CZ-CE2 4.38Å; F39-F136 HydrophobicContact CZ-CZ 4.3Å; V61-F136 HydrophobicContact CG1-CE1 4.27Å; V61-F136 HydrophobicContact CG1-CZ 4.36Å; W88-F136 HydrophobicContact CH2-CE2 4.27Å; W88-F136 AromaticContact CH2-CZ 3.89Å; W88-F136 HydrophobicContact CH2-CZ 3.89Å; W88-F136 HydrophobicContact CZ3-CZ 4.09Å; Y115-F136 VanDerWaalsContact CB-CE1 3.44Å; Y115-F136 HydrophobicContact CD1-CZ 4.2Å; Y115-F136 HydrophobicContact CD2-CE2 4.19Å; Y115-F136 HydrophobicContact CD2-CZ 4.38Å; Y115-F136 HydrophobicContact CG-CE1 4.29Å; Y115-F136 HydrophobicContact CG-CE2 4.01Å; Y115-F136 AromaticContact CG-CZ 3.75Å; Y115-F136 HydrophobicContact CG-CZ 3.75Å; Y115-F136 PolarHBondContact N-O 2.82Å; Y115-F136 PolarHBondContact O-N 2.86Å; L117-F136 HydrophobicContact CB-CD1 4.23Å; L117-F136 HydrophobicContact CB-CE1 4.11Å; F136-L138 HydrophobicContact CE2-CB 4.19Å; F136-L138 HydrophobicContact CE2-CD1 4.37Å
137I98.8Very high95.3Very high16 Ų1644 Ų448%0.08225%0.247CC..EExtended strand (participates in β ladder)trans-105.3132.7173-63.1167.8000108.6L31 L32 V33 G113 R114 L139 I191 L195L31-I137 PolarHBondContact O-N 2.6Å; L32-I137 HydrophobicContact CD1-CD1 4.37Å; L32-I137 HydrophobicContact CG-CB 4.09Å; L32-I137 HydrophobicContact CG-CD1 4.26Å; V33-I137 PolarHBondContact N-O 2.83Å; G113-I137 WeakPolarHBondContact O-CA 3.48Å; R114-I137 HydrophobicContact CG-CG1 4.18Å; I137-L139 HydrophobicContact CG2-CD2 3.68Å; I137-L139 HydrophobicContact CG2-CG 4.16Å; I137-I191 HydrophobicContact CD1-CG1 4Å; I137-L195 HydrophobicContact CD1-CD1 3.9Å; I137-L195 HydrophobicContact CG1-CD1 4.12Å; I137-L195 HydrophobicContact CG2-CD1 4.04Å
138L98.9Very high96.5Very high1 Ų140.1 Ų40.11%0.00522%0.221CC..EExtended strand (participates in β ladder)trans-106.2125.5173.9-165.266.3000110V33 R35 W88 A106 A110 V112 G113 Y115 F136V33-L138 HydrophobicContact CG2-CD1 3.81Å; V33-L138 CarbonylContact O-C 3.6Å; V33-L138 WeakPolarHBondContact O-CA 3.38Å; R35-L138 HydrophobicContact CB-CD1 4.09Å; R35-L138 HydrophobicContact CB-CD2 4.04Å; R35-L138 HydrophobicContact CB-CG 4.03Å; W88-L138 HydrophobicContact CH2-CD2 4.01Å; W88-L138 HydrophobicContact CZ2-CD2 4.11Å; A106-L138 HydrophobicContact CB-CD1 4.14Å; A106-L138 HydrophobicContact CB-CD2 3.77Å; A110-L138 HydrophobicContact CB-CD2 3.61Å; V112-L138 CarbonylContact C-O 3.59Å; V112-L138 VanDerWaalsContact CA-O 3.25Å; V112-L138 WeakPolarHBondContact CA-O 3.43Å; V112-L138 VanDerWaalsContact CB-O 3.31Å; V112-L138 WeakPolarHBondContact CB-O 3.46Å; G113-L138 PolarHBondContact N-O 2.99Å; G113-L138 PolarHBondContact O-N 2.76Å; Y115-L138 HydrophobicContact CD2-CB 3.78Å; Y115-L138 HydrophobicContact CE2-CB 3.72Å; Y115-L138 HydrophobicContact CE2-CD2 3.86Å; Y115-L138 HydrophobicContact CE2-CG 4.46Å; F136-L138 HydrophobicContact CE2-CB 4.19Å; F136-L138 HydrophobicContact CE2-CD1 4.37Å
139L98.9Very high97.3Very high0 Ų035.8 Ų35.80%020%0.195CC..EExtended strand (participates in β ladder)trans-113.1168.2-180-57.4-179.6000112.1T23 I26 V33 R34 R35 I137 I191T23-L139 HydrophobicContact CG2-CD1 4.13Å; I26-L139 HydrophobicContact CD1-CD1 4.23Å; V33-L139 PolarHBondContact O-N 2.68Å; R34-L139 WeakPolarHBondContact CA-O 3.48Å; R34-L139 HydrophobicContact CG-CB 4.34Å; R35-L139 PolarHBondContact N-O 2.94Å; I137-L139 HydrophobicContact CG2-CD2 3.68Å; I137-L139 HydrophobicContact CG2-CG 4.16Å; L139-I191 HydrophobicContact CD2-CD1 3.87Å
140F98.9Very high97.8Very high0 Ų037.9 Ų37.90%020%0.199CC..  trans-63150.2167.8-73-77.1000110.9R34 R35 V112 P142 V149 P218 V221 L292 I294R34-F140 PolarHBondContact NH1-O 3.08Å; R35-F140 VanDerWaalsContact CZ-CE1 3.43Å; R35-F140 VanDerWaalsContact NH2-CE1 3.28Å; V112-F140 HydrophobicContact CB-CD2 4.45Å; V112-F140 HydrophobicContact CB-CE2 4.28Å; V112-F140 HydrophobicContact CG1-CD1 4.14Å; V112-F140 HydrophobicContact CG1-CD2 3.65Å; V112-F140 HydrophobicContact CG1-CE1 4.17Å; V112-F140 HydrophobicContact CG1-CE2 3.69Å; V112-F140 HydrophobicContact CG1-CG 3.85Å; V112-F140 HydrophobicContact CG1-CZ 3.95Å; V112-F140 HydrophobicContact CG2-CD2 4.18Å; V112-F140 HydrophobicContact CG2-CE2 3.61Å; V112-F140 HydrophobicContact CG2-CZ 4.12Å; F140-P142 WeakPolarHBondContact O-CD 3.4Å; F140-V149 HydrophobicContact CB-CG2 3.79Å; F140-V149 HydrophobicContact CD1-CG1 4.14Å; F140-V149 HydrophobicContact CD1-CG2 4.36Å; F140-V149 HydrophobicContact CG-CG2 4.46Å; F140-P218 HydrophobicContact CD1-CB 4.41Å; F140-P218 HydrophobicContact CE1-CB 3.85Å; F140-P218 HydrophobicContact CE1-CG 4.35Å; F140-P218 HydrophobicContact CZ-CB 4.12Å; F140-V221 HydrophobicContact CE2-CB 4.17Å; F140-V221 HydrophobicContact CE2-CG1 4.13Å; F140-V221 HydrophobicContact CE2-CG2 4.04Å; F140-V221 HydrophobicContact CZ-CB 4.22Å; F140-V221 HydrophobicContact CZ-CG2 3.9Å; F140-L292 WeakPolarHBondContact CB-O 3.24Å; F140-L292 HydrophobicContact CD2-CB 4.45Å; F140-L292 WeakPolarHBondContact CD2-O 3.1Å; F140-L292 PolarHBondContact N-O 2.9Å; F140-I294 HydrophobicContact CB-CG1 4.41Å; F140-I294 HydrophobicContact CD2-CD1 3.94Å; F140-I294 HydrophobicContact CD2-CG1 3.51Å; F140-I294 HydrophobicContact CE2-CD1 3.77Å; F140-I294 HydrophobicContact CE2-CG1 3.91Å; F140-I294 HydrophobicContact CG-CG1 3.96Å; F140-I294 HydrophobicContact CZ-CD1 4.37Å
141N98.9Very high98.1Very high1 Ų134.7 Ų34.71%0.00517%0.173CC..  trans-121.692.7-174.7-161.7-12.3000113.7R34 R35 Q37 W143 C144 D147R34-N141 HydrophobicContact CB-CB 3.64Å; R35-N141 HydrophobicContact CG-CB 4.33Å; R35-N141 WeakPolarHBondContact O-CB 3.28Å; R35-N141 PolarHBondContact O-ND2 3.16Å; Q37-N141 WeakPolarHBondContact CB-ND2 3.49Å; Q37-N141 PolarHBondContact OE1-ND2 2.59Å; N141-W143 PolarHBondContact O-N 3.23Å; N141-W143 WeakPolarHBondContact OD1-CB 3.37Å; N141-W143 PolarHBondContact OD1-N 3.22Å; N141-C144 HydrophobicContact CB-CB 3.82Å; N141-C144 PolarHBondContact O-N 3.41Å; N141-C144 PolarHBondContact OD1-N 3.09Å; N141-D147 WeakPolarHBondContact CA-OD2 3.29Å; N141-D147 HydrophobicContact CB-CB 4.46Å; N141-D147 WeakPolarHBondContact CB-OD2 3.24Å; N141-D147 PolarHBondContact N-OD2 2.75Å; N141-D147 VanDerWaalsContact O-CB 3.25Å; N141-D147 WeakPolarHBondContact O-CB 3.42Å
142P98.8Very high98.2Very high0 Ų037.3 Ų37.30%019%0.191CC..THydrogen-bonded Turntrans-73-6.5176.925-25.8000113.8F140 V149 Y150 L151 R157 V161 G293 P295F140-P142 WeakPolarHBondContact O-CD 3.4Å; P142-V149 WeakPolarHBondContact CA-O 3.46Å; P142-V149 HydrophobicContact CB-CG2 4.34Å; P142-V149 WeakPolarHBondContact CB-O 3.33Å; P142-Y150 WeakPolarHBondContact O-CD2 3.26Å; P142-L151 PolarHBondContact O-N 2.9Å; P142-R157 HydrophobicContact CB-CG 4.45Å; P142-R157 VanDerWaalsContact O-CD 3.31Å; P142-R157 WeakPolarHBondContact O-CD 3.36Å; P142-V161 HydrophobicContact CB-CG2 4.49Å; P142-V161 HydrophobicContact CG-CG2 3.82Å; P142-G293 WeakPolarHBondContact CD-O 3.34Å; P142-P295 HydrophobicContact CB-CG 3.62Å; P142-P295 HydrophobicContact CG-CG 4.23Å
143W98.8Very high98.3Very high37 Ų3733 Ų3314%0.1417%0.174CC..THydrogen-bonded Turntrans-92.7-11173.2-69.9-97.6000113.7H22 N141 P145 E154 R157 V161 M162H22-W143 HydrophobicContact CB-CH2 3.9Å; H22-W143 HydrophobicContact CB-CZ2 4.16Å; H22-W143 HydrophobicContact CB-CZ3 4.1Å; H22-W143 AromaticContact CD2-CD2 3.49Å; H22-W143 VanDerWaalsContact CD2-CD2 3.49Å; H22-W143 AromaticContact CD2-CE2 3.48Å; H22-W143 VanDerWaalsContact CD2-CE2 3.48Å; H22-W143 AromaticContact CD2-CE3 3.85Å; H22-W143 AromaticContact CD2-CG 3.92Å; H22-W143 AromaticContact CD2-CZ2 3.89Å; H22-W143 AromaticContact CD2-NE1 3.8Å; H22-W143 AromaticContact CG-CE2 3.99Å; H22-W143 AromaticContact CG-CZ2 3.93Å; H22-W143 AromaticContact NE2-CD1 3.75Å; H22-W143 AromaticContact NE2-CE2 3.81Å; H22-W143 AromaticContact NE2-NE1 3.62Å; N141-W143 PolarHBondContact O-N 3.23Å; N141-W143 WeakPolarHBondContact OD1-CB 3.37Å; N141-W143 PolarHBondContact OD1-N 3.22Å; W143-P145 WeakPolarHBondContact O-CD 3.43Å; W143-E154 PolarHBondContact NE1-OE2 2.59Å; W143-R157 HydrophobicContact CH2-CB 4.37Å; W143-R157 HydrophobicContact CZ2-CB 3.8Å; W143-R157 VanDerWaalsContact NE1-NE 3.1Å; W143-V161 HydrophobicContact CH2-CB 4.38Å; W143-V161 HydrophobicContact CH2-CG1 4.24Å; W143-V161 HydrophobicContact CZ3-CG1 4.34Å; W143-M162 HydrophobicContact CH2-CG 4.01Å; W143-M162 HydrophobicContact CH2-SD 3.87Å; W143-M162 HydrophobicContact CZ2-CG 4.32Å
144C98.7Very high98.4Very high7 Ų735.2 Ų35.25%0.04718%0.184CC..  trans-92.6115.3179.9170.80000110.6N141 E146 D147 Y150N141-C144 HydrophobicContact CB-CB 3.82Å; N141-C144 PolarHBondContact O-N 3.41Å; N141-C144 PolarHBondContact OD1-N 3.09Å; C144-E146 PolarHBondContact O-N 3.35Å; C144-E146 VanDerWaalsContact O-N 3.12Å; C144-E146 PolarHBondContact SG-OE2 2.84Å; C144-D147 HydrophobicContact CB-CB 4.02Å; C144-D147 WeakPolarHBondContact O-CB 3.47Å; C144-D147 PolarHBondContact O-N 3.18Å; C144-Y150 VanDerWaalsContact C-CD2 3.47Å; C144-Y150 VanDerWaalsContact O-CB 3.3Å; C144-Y150 WeakPolarHBondContact O-CB 3.49Å; C144-Y150 WeakPolarHBondContact O-CD2 3.38Å
145P98.4Very high98.5Very high78 Ų7836.8 Ų36.851%0.50619%0.191SC..THydrogen-bonded Turntrans-56-28.3-178.2-28.137.2000115.3W143 Y150W143-P145 WeakPolarHBondContact O-CD 3.43Å; P145-Y150 HydrophobicContact CB-CD1 4.5Å; P145-Y150 HydrophobicContact CB-CD2 4.47Å; P145-Y150 HydrophobicContact CB-CE1 4.38Å; P145-Y150 HydrophobicContact CB-CE2 4.36Å; P145-Y150 HydrophobicContact CG-CD2 4.42Å; P145-Y150 HydrophobicContact CG-CE2 3.98Å
146E98.3Very high98.6Very high128 Ų12833 Ų3360%0.59817%0.173SC*.THydrogen-bonded Turntrans-85.3-12.6-180-59.774.8-15600113.4P108 C144P108-E146 HydrophobicContact CB-CB 3.96Å; P108-E146 HydrophobicContact CG-CB 3.59Å; C144-E146 PolarHBondContact O-N 3.35Å; C144-E146 VanDerWaalsContact O-N 3.12Å; C144-E146 PolarHBondContact SG-OE2 2.84Å
147D98.8Very high98.6Very high6 Ų634 Ų343%0.03218%0.177CC..SBendtrans-73.8140.5176.4-163.6-37.2000110.3R35 P108 N141 C144 V149 Y150R35-D147 VanDerWaalsContact CG-OD2 3.32Å; R35-D147 WeakPolarHBondContact CG-OD2 3.19Å; R35-D147 IonicContact CZ-OD1 3.35Å; R35-D147 IonicContact CZ-OD2 3.21Å; R35-D147 IonicContact NE-OD1 3.68Å; R35-D147 PolarHBondContact NE-OD1 3.33Å; R35-D147 IonicContact NE-OD2 3.83Å; R35-D147 PolarHBondContact NE-OD2 3.2Å; R35-D147 IonicContact NH2-OD1 3.65Å; R35-D147 PolarHBondContact NH2-OD1 2.78Å; R35-D147 IonicContact NH2-OD2 2.92Å; P108-D147 HydrophobicContact CB-CB 4.42Å; N141-D147 WeakPolarHBondContact CA-OD2 3.29Å; N141-D147 HydrophobicContact CB-CB 4.46Å; N141-D147 WeakPolarHBondContact CB-OD2 3.24Å; N141-D147 PolarHBondContact N-OD2 2.75Å; N141-D147 VanDerWaalsContact O-CB 3.25Å; N141-D147 WeakPolarHBondContact O-CB 3.42Å; C144-D147 HydrophobicContact CB-CB 4.02Å; C144-D147 WeakPolarHBondContact O-CB 3.47Å; C144-D147 PolarHBondContact O-N 3.18Å; D147-V149 PolarHBondContact O-N 2.82Å; D147-V149 VanDerWaalsContact O-N 3.12Å; D147-V149 WeakPolarHBondContact OD1-CG2 3.45Å; D147-V149 PolarHBondContact OD1-N 2.78Å; D147-Y150 WeakPolarHBondContact O-CB 3.43Å; D147-Y150 PolarHBondContact O-N 2.95Å
148A98.6Very high98.6Very high20 Ų2036.4 Ų36.417%0.16519%0.188CC..THydrogen-bonded Turntrans-60.8-18.7175.500000113.6P218 M344 A345A148-P218 HydrophobicContact CB-CG 3.73Å; A148-M344 CarbonylContact O-C 3.5Å; A148-M344 VanDerWaalsContact O-CA 3.28Å; A148-M344 WeakPolarHBondContact O-CA 3.17Å; A148-A345 HydrophobicContact CB-CB 4.32Å; A148-A345 PolarHBondContact O-N 3.32Å
149V98.9Very high98.6Very high0 Ų036.8 Ų36.80%019%0.189CC..THydrogen-bonded Turntrans-100.912175.7-57.20000114F140 P142 D147 L151 P218 I294 M344F140-V149 HydrophobicContact CB-CG2 3.79Å; F140-V149 HydrophobicContact CD1-CG1 4.14Å; F140-V149 HydrophobicContact CD1-CG2 4.36Å; F140-V149 HydrophobicContact CG-CG2 4.46Å; P142-V149 WeakPolarHBondContact CA-O 3.46Å; P142-V149 HydrophobicContact CB-CG2 4.34Å; P142-V149 WeakPolarHBondContact CB-O 3.33Å; D147-V149 PolarHBondContact O-N 2.82Å; D147-V149 VanDerWaalsContact O-N 3.12Å; D147-V149 WeakPolarHBondContact OD1-CG2 3.45Å; D147-V149 PolarHBondContact OD1-N 2.78Å; V149-L151 PolarHBondContact O-N 2.8Å; V149-P218 HydrophobicContact CG1-CB 3.61Å; V149-P218 HydrophobicContact CG1-CG 3.95Å; V149-I294 HydrophobicContact CG1-CG1 4.3Å; V149-I294 HydrophobicContact CG1-CG2 4.38Å; V149-M344 HydrophobicContact CG1-CB 4.35Å
150Y98.8Very high98.6Very high82 Ų8237 Ų3732%0.32219%0.191SC..  trans-54.2126179179.2-119.1000112P142 C144 P145 D147 D152 W343P142-Y150 WeakPolarHBondContact O-CD2 3.26Å; C144-Y150 VanDerWaalsContact C-CD2 3.47Å; C144-Y150 VanDerWaalsContact O-CB 3.3Å; C144-Y150 WeakPolarHBondContact O-CB 3.49Å; C144-Y150 WeakPolarHBondContact O-CD2 3.38Å; P145-Y150 HydrophobicContact CB-CD1 4.5Å; P145-Y150 HydrophobicContact CB-CD2 4.47Å; P145-Y150 HydrophobicContact CB-CE1 4.38Å; P145-Y150 HydrophobicContact CB-CE2 4.36Å; P145-Y150 HydrophobicContact CG-CD2 4.42Å; P145-Y150 HydrophobicContact CG-CE2 3.98Å; D147-Y150 WeakPolarHBondContact O-CB 3.43Å; D147-Y150 PolarHBondContact O-N 2.95Å; Y150-D152 HydrophobicContact CE1-CB 3.95Å; Y150-W343 PolarHBondContact O-NE1 2.86Å
151L98.4Very high98.5Very high0 Ų037 Ų370%019%0.191CC..  trans-125.3110.2176.7-17665.7000107.9P142 V149 S153 Q156 R157 Y160 P295 W343P142-L151 PolarHBondContact O-N 2.9Å; V149-L151 PolarHBondContact O-N 2.8Å; L151-S153 VanDerWaalsContact C-N 3.35Å; L151-S153 PolarHBondContact O-N 2.8Å; L151-Q156 HydrophobicContact CD2-CB 3.59Å; L151-Q156 HydrophobicContact CG-CB 4.1Å; L151-R157 HydrophobicContact CB-CG 4.01Å; L151-R157 HydrophobicContact CD2-CG 4.19Å; L151-R157 HydrophobicContact CG-CG 4.3Å; L151-R157 VanDerWaalsContact O-CD 3.22Å; L151-R157 WeakPolarHBondContact O-CD 3.46Å; L151-R157 WeakPolarHBondContact O-CG 3.35Å; L151-R157 PolarHBondContact O-NH1 2.81Å; L151-Y160 HydrophobicContact CD2-CD2 4.01Å; L151-P295 HydrophobicContact CB-CG 4.33Å; L151-P295 HydrophobicContact CD2-CB 3.96Å; L151-P295 HydrophobicContact CD2-CG 4.23Å; L151-W343 HydrophobicContact CD1-CD2 3.53Å; L151-W343 VanDerWaalsContact CD1-CE2 3.4Å; L151-W343 HydrophobicContact CD1-CE3 4.04Å; L151-W343 HydrophobicContact CD1-CG 3.84Å; L151-W343 HydrophobicContact CD1-CH2 4.26Å; L151-W343 HydrophobicContact CD1-CZ2 3.8Å; L151-W343 HydrophobicContact CD1-CZ3 4.37Å
152D97.8Very high98.5Very high108 Ų10838.1 Ų38.158%0.57820%0.196SC*.  trans-60.8-39.4-16963.7-15.2000114.1Y150 E154 R157Y150-D152 HydrophobicContact CE1-CB 3.95Å; D152-E154 PolarHBondContact O-N 2.8Å; D152-R157 PolarHBondContact O-NH1 2.95Å; D152-R157 VanDerWaalsContact O-NH1 3.1Å
153S98.4Very high98.5Very high38 Ų3839.1 Ų39.127%0.26620%0.201SC..  trans-76.5113.8-174.3-178.60000112.4L151 Q156 R157L151-S153 VanDerWaalsContact C-N 3.35Å; L151-S153 PolarHBondContact O-N 2.8Å; S153-Q156 WeakPolarHBondContact O-CB 3.39Å; S153-Q156 PolarHBondContact O-N 2.86Å; S153-Q156 VanDerWaalsContact O-N 3.09Å; S153-Q156 WeakPolarHBondContact OG-CG 3.49Å; S153-R157 PolarHBondContact O-N 2.84Å
154E98.1Very high98.4Very high70 Ų7037.6 Ų37.633%0.32720%0.196SC..Hα-helixtrans-57.7-46.4175.9-178.959.4-15600113.3W143 D152 Q156 R157 Q158W143-E154 PolarHBondContact NE1-OE2 2.59Å; D152-E154 PolarHBondContact O-N 2.8Å; E154-Q156 PolarHBondContact O-N 2.84Å; E154-R157 PolarHBondContact O-N 2.96Å; E154-R157 VanDerWaalsContact O-N 3.11Å; E154-R157 IonicContact OE2-CZ 3.53Å; E154-R157 VanDerWaalsContact OE2-CZ 3.25Å; E154-R157 IonicContact OE2-NE 3.29Å; E154-R157 PolarHBondContact OE2-NE 2.84Å; E154-R157 IonicContact OE2-NH2 2.59Å; E154-R157 PolarHBondContact OE2-NH2 2.98Å; E154-Q158 WeakPolarHBondContact O-CG 3.22Å; E154-Q158 PolarHBondContact O-N 2.48Å; E154-Q158 PolarHBondContact OE1-NE2 3.43Å
155P98.4Very high98.3Very high51 Ų5138.2 Ų38.233%0.33120%0.197SC..Hα-helixtrans-55.3-36.8173.1-28.336.3000113.8Q158 E159 I432P155-Q158 PolarHBondContact O-N 3.46Å; P155-E159 PolarHBondContact O-N 2.72Å; P155-I432 HydrophobicContact CB-CG2 3.75Å; P155-I432 WeakPolarHBondContact O-CG2 3.35Å
156Q98.6Very high98.3Very high45 Ų4534.5 Ų34.521%0.2117%0.174CC..Hα-helixtrans-71.6-39.3176.9-67.3-178.1-1500112L151 S153 E154 Q158 E159 Y160 I432L151-Q156 HydrophobicContact CD2-CB 3.59Å; L151-Q156 HydrophobicContact CG-CB 4.1Å; S153-Q156 WeakPolarHBondContact O-CB 3.39Å; S153-Q156 PolarHBondContact O-N 2.86Å; S153-Q156 VanDerWaalsContact O-N 3.09Å; S153-Q156 WeakPolarHBondContact OG-CG 3.49Å; E154-Q156 PolarHBondContact O-N 2.84Å; Q156-Q158 VanDerWaalsContact C-N 3.3Å; Q156-Q158 PolarHBondContact O-N 3.17Å; Q156-E159 PolarHBondContact O-N 3.11Å; Q156-Y160 HydrophobicContact CB-CD2 3.77Å; Q156-Y160 HydrophobicContact CB-CE2 3.72Å; Q156-Y160 HydrophobicContact CG-CD2 4.41Å; Q156-Y160 HydrophobicContact CG-CE2 3.85Å; Q156-Y160 VanDerWaalsContact O-CB 3.31Å; Q156-Y160 WeakPolarHBondContact O-CB 3.5Å; Q156-Y160 WeakPolarHBondContact O-CD2 3.48Å; Q156-Y160 PolarHBondContact O-N 2.76Å; Q156-I432 HydrophobicContact CG-CD1 3.53Å; Q156-I432 HydrophobicContact CG-CG1 4.23Å
157R98.7Very high98.3Very high25 Ų2528.6 Ų28.69%0.09415%0.146CC..Hα-helixtrans-61-41.7173.1-69-172.5-67.4-117.53.8111.3P142 W143 L151 D152 S153 E154 V161 M162P142-R157 HydrophobicContact CB-CG 4.45Å; P142-R157 VanDerWaalsContact O-CD 3.31Å; P142-R157 WeakPolarHBondContact O-CD 3.36Å; W143-R157 HydrophobicContact CH2-CB 4.37Å; W143-R157 HydrophobicContact CZ2-CB 3.8Å; W143-R157 VanDerWaalsContact NE1-NE 3.1Å; L151-R157 HydrophobicContact CB-CG 4.01Å; L151-R157 HydrophobicContact CD2-CG 4.19Å; L151-R157 HydrophobicContact CG-CG 4.3Å; L151-R157 VanDerWaalsContact O-CD 3.22Å; L151-R157 WeakPolarHBondContact O-CD 3.46Å; L151-R157 WeakPolarHBondContact O-CG 3.35Å; L151-R157 PolarHBondContact O-NH1 2.81Å; D152-R157 PolarHBondContact O-NH1 2.95Å; D152-R157 VanDerWaalsContact O-NH1 3.1Å; S153-R157 PolarHBondContact O-N 2.84Å; E154-R157 PolarHBondContact O-N 2.96Å; E154-R157 VanDerWaalsContact O-N 3.11Å; E154-R157 IonicContact OE2-CZ 3.53Å; E154-R157 VanDerWaalsContact OE2-CZ 3.25Å; E154-R157 IonicContact OE2-NE 3.29Å; E154-R157 PolarHBondContact OE2-NE 2.84Å; E154-R157 IonicContact OE2-NH2 2.59Å; E154-R157 PolarHBondContact OE2-NH2 2.98Å; R157-V161 VanDerWaalsContact O-CB 3.28Å; R157-V161 WeakPolarHBondContact O-CB 3.3Å; R157-V161 PolarHBondContact O-N 3.39Å; R157-M162 PolarHBondContact O-N 3.4Å
158Q98.3Very high98.3Very high67 Ų6728.3 Ų28.331%0.31314%0.144SC..Iπ-helixtrans-62-45.1175-65.8-56.8-38.200111.8E154 P155 Q156 M162 N163E154-Q158 WeakPolarHBondContact O-CG 3.22Å; E154-Q158 PolarHBondContact O-N 2.48Å; E154-Q158 PolarHBondContact OE1-NE2 3.43Å; P155-Q158 PolarHBondContact O-N 3.46Å; Q156-Q158 VanDerWaalsContact C-N 3.3Å; Q156-Q158 PolarHBondContact O-N 3.17Å; Q158-M162 CarbonylContact O-C 3.55Å; Q158-M162 WeakPolarHBondContact O-CA 3.32Å; Q158-M162 WeakPolarHBondContact O-CB 3.47Å; Q158-M162 PolarHBondContact O-N 3.36Å; Q158-N163 PolarHBondContact O-N 2.92Å
159E98.6Very high98.2Very high9 Ų927.7 Ų27.74%0.04214%0.138CC..Iπ-helixtrans-71.3-40.6179.1-179.562.8-157.600113.8P155 Q156 N163 R290 K430 I432P155-E159 PolarHBondContact O-N 2.72Å; Q156-E159 PolarHBondContact O-N 3.11Å; E159-N163 WeakPolarHBondContact O-CB 3.1Å; E159-N163 PolarHBondContact OE1-ND2 2.93Å; E159-N163 PolarHBondContact OE2-ND2 3.04Å; E159-R290 PolarHBondContact O-NH1 2.93Å; E159-R290 VanDerWaalsContact O-NH1 3.12Å; E159-R290 PolarHBondContact O-NH2 3.47Å; E159-R290 VanDerWaalsContact O-NH2 3.12Å; E159-K430 WeakPolarHBondContact OE1-CD 3.5Å; E159-K430 IonicContact OE1-NZ 3.74Å; E159-K430 PolarHBondContact OE1-NZ 3.4Å; E159-K430 IonicContact OE2-NZ 3.97Å; E159-K430 PolarHBondContact OE2-NZ 3.03Å; E159-I432 HydrophobicContact CB-CB 4.49Å; E159-I432 HydrophobicContact CB-CG1 4.42Å; E159-I432 HydrophobicContact CB-CG2 4.21Å; E159-I432 HydrophobicContact CG-CG1 4.45Å
160Y98.8Very high97.8Very high6 Ų628.2 Ų28.22%0.02414%0.14CC..Iπ-helixtrans-99.2-2.3-167.8-54.8-44.8000114.1L151 Q156 R290 P295 T296 R297 W356 I432L151-Y160 HydrophobicContact CD2-CD2 4.01Å; Q156-Y160 HydrophobicContact CB-CD2 3.77Å; Q156-Y160 HydrophobicContact CB-CE2 3.72Å; Q156-Y160 HydrophobicContact CG-CD2 4.41Å; Q156-Y160 HydrophobicContact CG-CE2 3.85Å; Q156-Y160 VanDerWaalsContact O-CB 3.31Å; Q156-Y160 WeakPolarHBondContact O-CB 3.5Å; Q156-Y160 WeakPolarHBondContact O-CD2 3.48Å; Q156-Y160 PolarHBondContact O-N 2.76Å; Y160-R290 VanDerWaalsContact O-CG 3.31Å; Y160-R290 WeakPolarHBondContact O-CG 3.44Å; Y160-R290 PolarHBondContact O-NE 2.9Å; Y160-P295 WeakPolarHBondContact O-CA 3.48Å; Y160-T296 PolarHBondContact O-N 3.36Å; Y160-R297 HydrophobicContact CD1-CB 3.84Å; Y160-R297 HydrophobicContact CE1-CB 3.82Å; Y160-R297 HydrophobicContact CE1-CG 4.37Å; Y160-R297 PolarHBondContact OH-NH1 2.85Å; Y160-W356 HydrophobicContact CD1-CH2 4.4Å; Y160-W356 AromaticContact CD2-CH2 3.57Å; Y160-W356 HydrophobicContact CD2-CH2 3.57Å; Y160-W356 AromaticContact CD2-CZ2 3.76Å; Y160-W356 HydrophobicContact CD2-CZ2 3.76Å; Y160-W356 AromaticContact CE2-CH2 3.81Å; Y160-W356 HydrophobicContact CE2-CH2 3.81Å; Y160-W356 AromaticContact CE2-CZ2 3.52Å; Y160-W356 HydrophobicContact CE2-CZ2 3.52Å; Y160-W356 AromaticContact CG-CH2 3.9Å; Y160-W356 HydrophobicContact CG-CH2 3.9Å; Y160-W356 HydrophobicContact CG-CZ2 4.46Å; Y160-I432 HydrophobicContact CE2-CD1 4.49Å; Y160-I432 HydrophobicContact CE2-CG1 4.27Å; Y160-I432 WeakPolarHBondContact OH-CG1 3.37Å
161V98.7Very high97.3Very high0 Ų024.4 Ų24.40%013%0.126CC..Iπ-helixtrans-130.7-50.4175.5-173.20000110.8P142 W143 R157 Q185 P295P142-V161 HydrophobicContact CB-CG2 4.49Å; P142-V161 HydrophobicContact CG-CG2 3.82Å; W143-V161 HydrophobicContact CH2-CB 4.38Å; W143-V161 HydrophobicContact CH2-CG1 4.24Å; W143-V161 HydrophobicContact CZ3-CG1 4.34Å; R157-V161 VanDerWaalsContact O-CB 3.28Å; R157-V161 WeakPolarHBondContact O-CB 3.3Å; R157-V161 PolarHBondContact O-N 3.39Å; V161-Q185 PolarHBondContact O-NE2 3.22Å; V161-P295 HydrophobicContact CG2-CB 3.94Å; V161-P295 HydrophobicContact CG2-CG 3.89Å
162M98.2Very high96.8Very high23 Ų2324.5 Ų24.511%0.11313%0.127CC..Iπ-helixtrans-88.6-26.2-170.5-56-53.4-65.400114.6H22 E25 W143 R157 Q158 D164 F186H22-M162 HydrophobicContact CB-CE 4.4Å; H22-M162 HydrophobicContact CB-SD 4.27Å; E25-M162 HydrophobicContact CG-CE 4.45Å; W143-M162 HydrophobicContact CH2-CG 4.01Å; W143-M162 HydrophobicContact CH2-SD 3.87Å; W143-M162 HydrophobicContact CZ2-CG 4.32Å; R157-M162 PolarHBondContact O-N 3.4Å; Q158-M162 CarbonylContact O-C 3.55Å; Q158-M162 WeakPolarHBondContact O-CA 3.32Å; Q158-M162 WeakPolarHBondContact O-CB 3.47Å; Q158-M162 PolarHBondContact O-N 3.36Å; M162-D164 PolarHBondContact O-N 3.09Å; M162-F186 HydrophobicContact CE-CE2 3.95Å; M162-F186 HydrophobicContact CE-CZ 3.79Å; M162-F186 WeakPolarHBondContact O-CE2 3.06Å; M162-F186 HydrophobicContact SD-CE2 4.49Å; M162-F186 HydrophobicContact SD-CZ 3.9Å
163N97.8Very high96.4Very high21 Ų2122.2 Ų22.211%0.11211%0.112CC..  trans-72.3122.2177.6-170.2-3000110.1Q158 E159 Y165 Q185 R290Q158-N163 PolarHBondContact O-N 2.92Å; E159-N163 WeakPolarHBondContact O-CB 3.1Å; E159-N163 PolarHBondContact OE1-ND2 2.93Å; E159-N163 PolarHBondContact OE2-ND2 3.04Å; N163-Y165 VanDerWaalsContact CG-O 3.27Å; N163-Y165 PolarHBondContact ND2-O 2.88Å; N163-Y165 WeakPolarHBondContact OD1-CD1 3.37Å; N163-Y165 PolarHBondContact OD1-N 3.3Å; N163-Y165 PolarHBondContact OD1-O 2.86Å; N163-Q185 PolarHBondContact O-NE2 2.76Å; N163-R290 PolarHBondContact O-NH1 2.91Å
164D97.4Very high95.8Very high6 Ų624.8 Ų24.83%0.03212%0.123CC..  trans-103.26.7-174.868.2-8.1000114M162 N182 Y183 G184 Q185 F186 S660M162-D164 PolarHBondContact O-N 3.09Å; D164-N182 PolarHBondContact O-OD1 2.79Å; D164-Y183 WeakPolarHBondContact O-CA 3.41Å; D164-Y183 WeakPolarHBondContact O-CB 3.27Å; D164-Y183 PolarHBondContact O-N 2.86Å; D164-G184 PolarHBondContact O-N 3.08Å; D164-Q185 VanDerWaalsContact CA-OE1 3.32Å; D164-F186 HydrophobicContact CB-CD2 4.35Å; D164-S660 WeakPolarHBondContact OD2-CB 3.49Å
165Y97.6Very high95.3Very high19 Ų1928.1 Ų28.18%0.07513%0.132CC..EExtended strand (participates in β ladder)trans-133.9165.9168.167.4-90.9000110.6N163 W181 Q693 Q695N163-Y165 VanDerWaalsContact CG-O 3.27Å; N163-Y165 PolarHBondContact ND2-O 2.88Å; N163-Y165 WeakPolarHBondContact OD1-CD1 3.37Å; N163-Y165 PolarHBondContact OD1-N 3.3Å; N163-Y165 PolarHBondContact OD1-O 2.86Å; Y165-W181 WeakPolarHBondContact CA-O 3.12Å; Y165-Q693 HydrophobicContact CE1-CG 4.43Å; Y165-Q693 WeakPolarHBondContact OH-CG 3.35Å; Y165-Q695 HydrophobicContact CD1-CB 3.95Å; Y165-Q695 HydrophobicContact CD2-CB 3.61Å; Y165-Q695 VanDerWaalsContact CD2-CD 3.45Å; Y165-Q695 HydrophobicContact CD2-CG 4.15Å; Y165-Q695 HydrophobicContact CE1-CB 4.23Å; Y165-Q695 HydrophobicContact CE2-CB 3.93Å; Y165-Q695 HydrophobicContact CE2-CG 4.46Å; Y165-Q695 HydrophobicContact CG-CB 3.63Å
166G97.6Very high94.9Very high1 Ų127.8 Ų27.81%0.0113%0.127CC..EExtended strand (participates in β ladder)trans-173.9-163.6175.700000113.3P180 W181G166-P180 CarbonylContact O-C 3.43Å; G166-P180 WeakPolarHBondContact O-CA 3.31Å; G166-W181 PolarHBondContact N-O 3.21Å; G166-W181 PolarHBondContact O-N 3.43Å
167F97.9Very high94.5Very high3 Ų328.1 Ų28.11%0.01313%0.126CC..EExtended strand (participates in β ladder)trans-123.8141.4177.5-61.7-73.9000110.6Y169 P178 C179 P180 K430 D435 Y711F167-Y169 HydrophobicContact CB-CE2 4.37Å; F167-P178 HydrophobicContact CB-CB 4.27Å; F167-P178 HydrophobicContact CD1-CB 3.77Å; F167-P178 HydrophobicContact CE1-CB 4.41Å; F167-P178 HydrophobicContact CG-CB 4.08Å; F167-C179 WeakPolarHBondContact CA-O 3.32Å; F167-P180 HydrophobicContact CD1-CB 4.23Å; F167-P180 HydrophobicContact CE1-CB 3.98Å; F167-K430 HydrophobicContact CD2-CD 3.79Å; F167-K430 HydrophobicContact CD2-CG 4.1Å; F167-K430 HydrophobicContact CE2-CD 4.41Å; F167-D435 HydrophobicContact CD2-CB 4.42Å; F167-D435 HydrophobicContact CE2-CB 3.52Å; F167-D435 VanDerWaalsContact CE2-CG 3.43Å; F167-D435 WeakPolarHBondContact CE2-OD1 3.46Å; F167-D435 HydrophobicContact CZ-CB 4.06Å; F167-Y711 AromaticContact CE1-CD1 3.73Å; F167-Y711 HydrophobicContact CE1-CD1 3.73Å; F167-Y711 HydrophobicContact CE1-CD2 4.23Å; F167-Y711 AromaticContact CE1-CE1 3.51Å; F167-Y711 HydrophobicContact CE1-CE1 3.51Å; F167-Y711 HydrophobicContact CE1-CE2 4.04Å; F167-Y711 HydrophobicContact CE1-CG 4.09Å; F167-Y711 AromaticContact CE1-CZ 3.68Å; F167-Y711 HydrophobicContact CZ-CD1 4.27Å; F167-Y711 AromaticContact CZ-CD2 3.99Å; F167-Y711 HydrophobicContact CZ-CD2 3.99Å; F167-Y711 AromaticContact CZ-CE1 3.85Å; F167-Y711 HydrophobicContact CZ-CE1 3.85Å; F167-Y711 AromaticContact CZ-CE2 3.56Å; F167-Y711 HydrophobicContact CZ-CE2 3.56Å; F167-Y711 HydrophobicContact CZ-CG 4.33Å; F167-Y711 AromaticContact CZ-CZ 3.48Å; F167-Y711 VanDerWaalsContact CZ-CZ 3.48Å
168I98Very high94.3Very high1 Ų129.8 Ų29.81%0.00514%0.141CC..EExtended strand (participates in β ladder)trans-110.3127.4165.1-49.3171.5000106.5C179 W181 W279 A283 V298 V338I168-C179 PolarHBondContact N-O 3.35Å; I168-C179 WeakPolarHBondContact O-CA 3.12Å; I168-C179 VanDerWaalsContact O-CB 3.3Å; I168-C179 WeakPolarHBondContact O-CB 3.3Å; I168-C179 PolarHBondContact O-N 3.02Å; I168-W181 HydrophobicContact CD1-CB 3.99Å; I168-W181 HydrophobicContact CD1-CD2 3.83Å; I168-W181 HydrophobicContact CD1-CE3 3.76Å; I168-W181 HydrophobicContact CD1-CG 3.94Å; I168-W181 HydrophobicContact CD1-CZ3 4.48Å; I168-W181 HydrophobicContact CG1-CB 4.17Å; I168-W279 HydrophobicContact CD1-CB 4.2Å; I168-W279 HydrophobicContact CG2-CB 3.92Å; I168-A283 HydrophobicContact CD1-CB 3.66Å; I168-V298 HydrophobicContact CG1-CG1 4.22Å; I168-V298 HydrophobicContact CG2-CG1 4.11Å; I168-V338 HydrophobicContact CG2-CG1 3.87Å; I168-V338 HydrophobicContact CG2-CG2 4.13Å
169Y96.4Very high94.1Very high6 Ų627.1 Ų27.12%0.02413%0.129CC..EExtended strand (participates in β ladder)trans-83.2133.2-179.9-64.4-82.1000109.1F167 I176 R177 P178 T300 T429 E436 R437F167-Y169 HydrophobicContact CB-CE2 4.37Å; Y169-I176 HydrophobicContact CD1-CG2 3.7Å; Y169-I176 HydrophobicContact CG-CG2 4.18Å; Y169-R177 WeakPolarHBondContact CA-O 3.31Å; Y169-P178 HydrophobicContact CD1-CB 4.43Å; Y169-P178 HydrophobicContact CE1-CB 4.04Å; Y169-T300 PolarHBondContact N-OG1 3.38Å; Y169-T300 WeakPolarHBondContact O-CB 3.34Å; Y169-T300 WeakPolarHBondContact O-CG2 3.37Å; Y169-T300 PolarHBondContact O-OG1 3.38Å; Y169-T429 WeakPolarHBondContact CE2-O 3.46Å; Y169-E436 PolarHBondContact OH-O 2.78Å; Y169-R437 HydrophobicContact CD1-CB 4.31Å; Y169-R437 HydrophobicContact CD1-CG 3.92Å; Y169-R437 HydrophobicContact CD2-CG 4.37Å; Y169-R437 HydrophobicContact CE1-CB 3.53Å; Y169-R437 HydrophobicContact CE1-CG 3.59Å; Y169-R437 HydrophobicContact CE2-CB 4.49Å; Y169-R437 HydrophobicContact CE2-CG 4.12Å; Y169-R437 HydrophobicContact CG-CG 4.29Å; Y169-R437 WeakPolarHBondContact OH-CA 3.46Å; Y169-R437 PolarHBondContact OH-N 2.85Å
170Q92.1Very high94Very high11 Ų1127 Ų275%0.05113%0.129CC..EExtended strand (participates in β ladder)trans-135.6-179.2179.8-60-173.40.100110R177 C179 F336Q170-R177 HydrophobicContact CB-CG 4.16Å; Q170-R177 PolarHBondContact N-O 3.44Å; Q170-R177 WeakPolarHBondContact O-CG 3.25Å; Q170-R177 PolarHBondContact O-N 3.12Å; Q170-C179 VanDerWaalsContact CD-SG 3.51Å; Q170-C179 HydrophobicContact CG-CB 4.29Å; Q170-C179 PolarHBondContact OE1-SG 2.99Å; Q170-F336 HydrophobicContact CB-CE1 4.02Å; Q170-F336 HydrophobicContact CB-CE2 4.17Å; Q170-F336 HydrophobicContact CB-CZ 3.72Å; Q170-F336 HydrophobicContact CG-CE1 4.47Å; Q170-F336 HydrophobicContact CG-CE2 3.82Å; Q170-F336 HydrophobicContact CG-CZ 3.68Å
171G88Confident94Very high3 Ų327 Ų273%0.03113%0.129CC..EExtended strand (participates in β ladder)trans103.4-128.6178.200000111.1F336G171-F336 WeakPolarHBondContact O-CD1 3.08Å
172S87.7Confident94Very high2 Ų227.2 Ų27.21%0.01413%0.13CC..EExtended strand (participates in β ladder)trans-138168.2174.370.20000110.6N174 W175 I176 T616S172-N174 PolarHBondContact O-N 2.97Å; S172-W175 PolarHBondContact N-O 3.42Å; S172-W175 CarbonylContact O-C 3.55Å; S172-W175 PolarHBondContact O-N 2.69Å; S172-I176 WeakPolarHBondContact O-CG1 3.48Å; S172-I176 PolarHBondContact O-N 2.74Å; S172-T616 PolarHBondContact OG-OG1 3.49Å
173K88.6Confident94Very high60 Ų6026.4 Ų26.426%0.26113%0.126SC..THydrogen-bonded Turntrans-53.6-25.1176.365.4161.7162.5-139.70114.8F302 D303 N425 F426K173-F302 HydrophobicContact CB-CB 4.08Å; K173-D303 WeakPolarHBondContact CD-OD2 3.48Å; K173-D303 WeakPolarHBondContact CE-OD2 3.48Å; K173-D303 WeakPolarHBondContact CG-OD2 3.38Å; K173-D303 IonicContact NZ-OD2 3.25Å; K173-D303 PolarHBondContact NZ-OD2 3.38Å; K173-N425 HydrophobicContact CB-CB 4.49Å; K173-N425 HydrophobicContact CD-CB 4.49Å; K173-F426 HydrophobicContact CB-CD2 3.62Å; K173-F426 HydrophobicContact CB-CE2 3.8Å; K173-F426 HydrophobicContact CD-CE2 4.49Å; K173-F426 WeakPolarHBondContact O-CE2 3.43Å
174N85.9Confident94Very high92 Ų9225.4 Ų25.449%0.49212%0.121SC..THydrogen-bonded Turntrans-89-15.5179.6-60.3-58.1000113S172S172-N174 PolarHBondContact O-N 2.97Å
175W87.3Confident94.1Very high140 Ų14025.1 Ų25.153%0.5312%0.119SC..EExtended strand (participates in β ladder)trans-152.982.4-176.8-166.8-91.6000109.9S172 T616S172-W175 PolarHBondContact N-O 3.42Å; S172-W175 CarbonylContact O-C 3.55Å; S172-W175 PolarHBondContact O-N 2.69Å; W175-T616 HydrophobicContact CB-CG2 4.43Å; W175-T616 HydrophobicContact CG-CG2 4.49Å
176I91.8Very high94.1Very high43 Ų4324.5 Ų24.522%0.22112%0.117CC..EExtended strand (participates in β ladder)trans-84.1122.1179.9-60.2175.8000108.5Y169 S172 F302 F426Y169-I176 HydrophobicContact CD1-CG2 3.7Å; Y169-I176 HydrophobicContact CG-CG2 4.18Å; S172-I176 WeakPolarHBondContact O-CG1 3.48Å; S172-I176 PolarHBondContact O-N 2.74Å; I176-F302 HydrophobicContact CB-CZ 4.18Å; I176-F302 HydrophobicContact CD1-CD2 4.1Å; I176-F302 HydrophobicContact CD1-CE2 3.71Å; I176-F302 HydrophobicContact CD1-CZ 4.16Å; I176-F302 HydrophobicContact CG1-CD2 4.35Å; I176-F302 HydrophobicContact CG1-CE1 4.17Å; I176-F302 HydrophobicContact CG1-CE2 3.78Å; I176-F302 HydrophobicContact CG1-CZ 3.69Å; I176-F302 HydrophobicContact CG2-CE2 4.07Å; I176-F302 HydrophobicContact CG2-CZ 3.76Å; I176-F426 HydrophobicContact CD1-CB 3.62Å; I176-F426 HydrophobicContact CD1-CD2 4.44Å; I176-F426 HydrophobicContact CD1-CG 3.96Å
177R89.3Confident94Very high52 Ų5225.2 Ų25.220%0.19612%0.12CC..EExtended strand (participates in β ladder)trans-110.8136176.964.4176-173.1156.87111.1Y169 Q170 D707Y169-R177 WeakPolarHBondContact CA-O 3.31Å; Q170-R177 HydrophobicContact CB-CG 4.16Å; Q170-R177 PolarHBondContact N-O 3.44Å; Q170-R177 WeakPolarHBondContact O-CG 3.25Å; Q170-R177 PolarHBondContact O-N 3.12Å; R177-D707 IonicContact CZ-OD2 3.38Å; R177-D707 IonicContact NH1-OD2 2.71Å; R177-D707 PolarHBondContact NH1-OD2 2.7Å; R177-D707 IonicContact NH2-OD2 3.8Å; R177-D707 PolarHBondContact NH2-OD2 2.67Å
178P93.8Very high93.9Very high61 Ų6131 Ų3140%0.39615%0.147SC..EExtended strand (participates in β ladder)trans-75.8127.1167.730.6-31.8000109.7F167 Y169F167-P178 HydrophobicContact CB-CB 4.27Å; F167-P178 HydrophobicContact CD1-CB 3.77Å; F167-P178 HydrophobicContact CE1-CB 4.41Å; F167-P178 HydrophobicContact CG-CB 4.08Å; Y169-P178 HydrophobicContact CD1-CB 4.43Å; Y169-P178 HydrophobicContact CE1-CB 4.04Å
179C94.7Very high93.8Very high10 Ų1036.6 Ų36.67%0.06817%0.171CC..EExtended strand (participates in β ladder)trans-109114.4171.6-66.30000108.8F167 I168 Q170F167-C179 WeakPolarHBondContact CA-O 3.32Å; I168-C179 PolarHBondContact N-O 3.35Å; I168-C179 WeakPolarHBondContact O-CA 3.12Å; I168-C179 VanDerWaalsContact O-CB 3.3Å; I168-C179 WeakPolarHBondContact O-CB 3.3Å; I168-C179 PolarHBondContact O-N 3.02Å; Q170-C179 VanDerWaalsContact CD-SG 3.51Å; Q170-C179 HydrophobicContact CG-CB 4.29Å; Q170-C179 PolarHBondContact OE1-SG 2.99Å
180P96.9Very high93.9Very high6 Ų636.3 Ų36.34%0.03917%0.17CC..EExtended strand (participates in β ladder)trans-65.1142.9-179.229.4-36.4000110.5G166 F167 Q697 K709 Y711G166-P180 CarbonylContact O-C 3.43Å; G166-P180 WeakPolarHBondContact O-CA 3.31Å; F167-P180 HydrophobicContact CD1-CB 4.23Å; F167-P180 HydrophobicContact CE1-CB 3.98Å; P180-Q697 HydrophobicContact CB-CG 3.99Å; P180-K709 HydrophobicContact CG-CB 4.25Å; P180-Y711 HydrophobicContact CB-CD1 4.22Å; P180-Y711 HydrophobicContact CB-CG 4.2Å; P180-Y711 HydrophobicContact CG-CD1 4.2Å; P180-Y711 HydrophobicContact CG-CG 4.46Å
181W98.4Very high94.2Very high6 Ų636.3 Ų36.32%0.02317%0.17CC..EExtended strand (participates in β ladder)trans-138.9132.9177.6-165.3-87.1000111.6Y165 G166 I168 Y183 W255 S258 I261 W279 V280 A283 Q697Y165-W181 WeakPolarHBondContact CA-O 3.12Å; G166-W181 PolarHBondContact N-O 3.21Å; G166-W181 PolarHBondContact O-N 3.43Å; I168-W181 HydrophobicContact CD1-CB 3.99Å; I168-W181 HydrophobicContact CD1-CD2 3.83Å; I168-W181 HydrophobicContact CD1-CE3 3.76Å; I168-W181 HydrophobicContact CD1-CG 3.94Å; I168-W181 HydrophobicContact CD1-CZ3 4.48Å; I168-W181 HydrophobicContact CG1-CB 4.17Å; W181-Y183 AromaticContact CD1-CD1 3.66Å; W181-Y183 AromaticContact CD1-CE1 3.86Å; W181-W255 HydrophobicContact CH2-CB 3.51Å; W181-W255 HydrophobicContact CH2-CG 4.5Å; W181-W255 HydrophobicContact CZ2-CB 4.45Å; W181-W255 HydrophobicContact CZ3-CB 3.95Å; W181-W255 WeakPolarHBondContact CZ3-O 3.1Å; W181-S258 PolarHBondContact NE1-OG 3.33Å; W181-I261 HydrophobicContact CZ2-CD1 4.31Å; W181-W279 AromaticContact CZ3-CD1 3.95Å; W181-V280 HydrophobicContact CH2-CB 4.39Å; W181-V280 HydrophobicContact CH2-CG1 4.11Å; W181-V280 HydrophobicContact CH2-CG2 4.21Å; W181-V280 HydrophobicContact CZ2-CG1 4.48Å; W181-A283 HydrophobicContact CD2-CB 3.77Å; W181-A283 HydrophobicContact CG-CB 3.96Å; W181-A283 HydrophobicContact CZ2-CB 3.75Å; W181-A283 VanDerWaalsContact NE1-CB 3.26Å; W181-Q697 VanDerWaalsContact C-OE1 3.27Å; W181-Q697 PolarHBondContact O-NE2 2.93Å
182N98.4Very high94.7Very high6 Ų638.8 Ų38.83%0.03218%0.183CC..EExtended strand (participates in β ladder)trans-91.1101.5174.6-179.531.8000109.1D164 T256 G257 S258 E658 S660D164-N182 PolarHBondContact O-OD1 2.79Å; N182-T256 PolarHBondContact N-O 2.94Å; N182-G257 CarbonylContact O-C 3.56Å; N182-G257 WeakPolarHBondContact O-CA 3.45Å; N182-S258 PolarHBondContact O-N 3.05Å; N182-E658 HydrophobicContact CB-CG 4.4Å; N182-E658 PolarHBondContact ND2-OE2 2.92Å; N182-S660 PolarHBondContact ND2-OG 3.1Å; N182-S660 PolarHBondContact OD1-OG 2.95Å
183Y98.7Very high95.2Very high6 Ų638.8 Ų38.82%0.02418%0.183CC..  trans-68.5-51.8174.5-61.5-61.3000109.5D164 W181 Q185 A283 C286 T287 V298D164-Y183 WeakPolarHBondContact O-CA 3.41Å; D164-Y183 WeakPolarHBondContact O-CB 3.27Å; D164-Y183 PolarHBondContact O-N 2.86Å; W181-Y183 AromaticContact CD1-CD1 3.66Å; W181-Y183 AromaticContact CD1-CE1 3.86Å; Y183-Q185 VanDerWaalsContact C-N 3.31Å; Y183-Q185 VanDerWaalsContact CB-OE1 3.31Å; Y183-Q185 PolarHBondContact O-N 3.39Å; Y183-A283 HydrophobicContact CE1-CB 4.12Å; Y183-C286 HydrophobicContact CD1-CB 4.1Å; Y183-C286 HydrophobicContact CE1-CB 3.77Å; Y183-T287 WeakPolarHBondContact CA-OG1 3.47Å; Y183-T287 WeakPolarHBondContact O-CG2 3.1Å; Y183-T287 PolarHBondContact O-OG1 2.91Å; Y183-V298 HydrophobicContact CE1-CG2 3.96Å; Y183-V298 WeakPolarHBondContact OH-CG2 3.48Å
184G97.9Very high95.7Very high0 Ų036 Ų360%017%0.17CC..  trans59.836.9173.300000113.7D164 F186 E187 S660D164-G184 PolarHBondContact O-N 3.08Å; G184-F186 PolarHBondContact O-N 3.09Å; G184-E187 WeakPolarHBondContact O-CB 3.45Å; G184-E187 PolarHBondContact O-N 2.96Å; G184-S660 VanDerWaalsContact CA-OG 3.23Å; G184-S660 WeakPolarHBondContact CA-OG 3.38Å
185Q98.5Very high96.3Very high0 Ų031.7 Ų31.70%015%0.148CC..THydrogen-bonded Turntrans-60.2-15.3-179.363.5-88.621.400114.1V161 N163 D164 Y183 T287 R290 C291V161-Q185 PolarHBondContact O-NE2 3.22Å; N163-Q185 PolarHBondContact O-NE2 2.76Å; D164-Q185 VanDerWaalsContact CA-OE1 3.32Å; Y183-Q185 VanDerWaalsContact C-N 3.31Å; Y183-Q185 VanDerWaalsContact CB-OE1 3.31Å; Y183-Q185 PolarHBondContact O-N 3.39Å; Q185-T287 HydrophobicContact CB-CG2 4.05Å; Q185-R290 HydrophobicContact CB-CB 4.39Å; Q185-R290 HydrophobicContact CG-CB 4.02Å; Q185-C291 HydrophobicContact CB-CB 3.9Å; Q185-C291 PolarHBondContact O-SG 2.94Å; Q185-C291 VanDerWaalsContact O-SG 3.37Å
186F97.4Very high96.8Very high6 Ų628.6 Ų28.63%0.02614%0.138CC..THydrogen-bonded Turntrans-1066.2179.7-52.5-34.9000113.5E25 I26 M162 D164 G184 K690E25-F186 HydrophobicContact CB-CB 4.2Å; E25-F186 HydrophobicContact CB-CD2 3.57Å; E25-F186 HydrophobicContact CB-CE2 3.96Å; E25-F186 HydrophobicContact CB-CG 3.86Å; E25-F186 HydrophobicContact CG-CD2 4.22Å; E25-F186 HydrophobicContact CG-CE2 4.41Å; I26-F186 HydrophobicContact CD1-CD1 4.21Å; I26-F186 HydrophobicContact CD1-CE1 4.33Å; I26-F186 HydrophobicContact CG1-CD1 3.46Å; I26-F186 VanDerWaalsContact CG1-CD1 3.46Å; I26-F186 HydrophobicContact CG1-CE1 4Å; I26-F186 HydrophobicContact CG1-CG 4.29Å; M162-F186 HydrophobicContact CE-CE2 3.95Å; M162-F186 HydrophobicContact CE-CZ 3.79Å; M162-F186 WeakPolarHBondContact O-CE2 3.06Å; M162-F186 HydrophobicContact SD-CE2 4.49Å; M162-F186 HydrophobicContact SD-CZ 3.9Å; D164-F186 HydrophobicContact CB-CD2 4.35Å; G184-F186 PolarHBondContact O-N 3.09Å; F186-K690 PolarHBondContact O-NZ 2.57Å
187E97Very high97.1Very high15 Ų1526.6 Ų26.67%0.0713%0.128CC..SBendtrans-71.5155173.8-72.6-64.7133.200111G184 K189 I190 V259 S660 G661G184-E187 WeakPolarHBondContact O-CB 3.45Å; G184-E187 PolarHBondContact O-N 2.96Å; E187-K189 PolarHBondContact O-N 3.06Å; E187-I190 HydrophobicContact CB-CG1 3.97Å; E187-I190 WeakPolarHBondContact O-CB 3.34Å; E187-I190 WeakPolarHBondContact O-CG1 3.18Å; E187-I190 PolarHBondContact O-N 3.39Å; E187-I190 VanDerWaalsContact O-N 3.07Å; E187-V259 HydrophobicContact CB-CG1 4.08Å; E187-V259 HydrophobicContact CB-CG2 4.13Å; E187-V259 HydrophobicContact CG-CG1 4.38Å; E187-V259 HydrophobicContact CG-CG2 3.97Å; E187-S660 WeakPolarHBondContact CG-OG 3.15Å; E187-S660 VanDerWaalsContact OE1-CA 3.24Å; E187-S660 WeakPolarHBondContact OE1-CA 3.19Å; E187-S660 VanDerWaalsContact OE1-CB 3.29Å; E187-S660 WeakPolarHBondContact OE1-CB 3.22Å; E187-G661 PolarHBondContact OE1-N 2.75Å
188E94.5Very high97.6Very high126 Ų12624.2 Ų24.259%0.58912%0.119SC*.THydrogen-bonded Turntrans-51.5133.7-174.5-163-157.2141.800111.9I190 K263E188-I190 PolarHBondContact O-N 3.26Å; E188-K263 WeakPolarHBondContact O-CE 3.29Å; E188-K263 PolarHBondContact O-NZ 2.82Å; E188-K263 VanDerWaalsContact O-NZ 3.09Å
189K95.6Very high97.8Very high117 Ų11723 Ų2351%0.50911%0.109SC..THydrogen-bonded Turntrans67.5-3.7-178.7-55.7-178179.6177.60116.4E187 I191 D192 I193E187-K189 PolarHBondContact O-N 3.06Å; K189-I191 VanDerWaalsContact C-N 3.35Å; K189-I191 PolarHBondContact O-N 3.25Å; K189-D192 PolarHBondContact O-N 2.88Å; K189-D192 VanDerWaalsContact O-N 3.14Å; K189-I193 HydrophobicContact CB-CD1 4.37Å; K189-I193 VanDerWaalsContact O-CG1 3.24Å; K189-I193 WeakPolarHBondContact O-CG1 3.3Å; K189-I193 PolarHBondContact O-N 3.46Å
190I98.4Very high97.9Very high0 Ų026 Ų260%012%0.121CC..Hα-helixtrans-62.7-42.2-177.4-65.6-65.5000111.5E187 E188 D192 I193 C194 V259 L262 K263 T287E187-I190 HydrophobicContact CB-CG1 3.97Å; E187-I190 WeakPolarHBondContact O-CB 3.34Å; E187-I190 WeakPolarHBondContact O-CG1 3.18Å; E187-I190 PolarHBondContact O-N 3.39Å; E187-I190 VanDerWaalsContact O-N 3.07Å; E188-I190 PolarHBondContact O-N 3.26Å; I190-D192 VanDerWaalsContact C-N 3.29Å; I190-D192 PolarHBondContact O-N 3.08Å; I190-I193 HydrophobicContact CD1-CD1 4.3Å; I190-I193 PolarHBondContact O-N 2.92Å; I190-I193 VanDerWaalsContact O-N 3.16Å; I190-C194 PolarHBondContact O-N 2.8Å; I190-C194 PolarHBondContact O-SG 2.98Å; I190-V259 HydrophobicContact CD1-CB 4.48Å; I190-V259 HydrophobicContact CD1-CG1 4.19Å; I190-L262 HydrophobicContact CD1-CB 4.05Å; I190-L262 HydrophobicContact CD1-CD1 4.2Å; I190-L262 HydrophobicContact CG2-CD1 4.36Å; I190-K263 HydrophobicContact CD1-CG 4.36Å; I190-T287 HydrophobicContact CG2-CG2 4.32Å
191I98.4Very high98Very high11 Ų1125.7 Ų25.76%0.05612%0.119CC..Hα-helixtrans-58.3-41.3174.4-176.558.2000112.5I26 L32 I137 L139 K189 I193 C194 L195 C291I26-I191 HydrophobicContact CG2-CB 4.15Å; I26-I191 HydrophobicContact CG2-CG2 3.75Å; L32-I191 HydrophobicContact CD2-CG1 4.41Å; I137-I191 HydrophobicContact CD1-CG1 4Å; L139-I191 HydrophobicContact CD2-CD1 3.87Å; K189-I191 VanDerWaalsContact C-N 3.35Å; K189-I191 PolarHBondContact O-N 3.25Å; I191-I193 VanDerWaalsContact C-N 3.32Å; I191-I193 PolarHBondContact O-N 3.44Å; I191-C194 PolarHBondContact O-N 2.81Å; I191-L195 HydrophobicContact CD1-CD1 4.42Å; I191-L195 HydrophobicContact CD1-CG 4.29Å; I191-L195 HydrophobicContact CG1-CD1 4.33Å; I191-L195 WeakPolarHBondContact O-CG 3.2Å; I191-L195 PolarHBondContact O-N 2.66Å; I191-C291 VanDerWaalsContact CA-SG 3.52Å
192D98.4Very high97.8Very high56 Ų5628.6 Ų28.630%0.29914%0.135SC..Hα-helixtrans-66.1-38179.2-65.9-58.6000112.3R114 K189 I190 K196R114-D192 IonicContact CZ-OD1 3.49Å; R114-D192 IonicContact NE-OD1 2.74Å; R114-D192 VanDerWaalsContact NH2-CA 3.28Å; R114-D192 PolarHBondContact NH2-O 3.07Å; R114-D192 IonicContact NH2-OD1 3.56Å; R114-D192 PolarHBondContact NH2-OD1 3.18Å; K189-D192 PolarHBondContact O-N 2.88Å; K189-D192 VanDerWaalsContact O-N 3.14Å; I190-D192 VanDerWaalsContact C-N 3.29Å; I190-D192 PolarHBondContact O-N 3.08Å; D192-K196 WeakPolarHBondContact O-CB 3.33Å; D192-K196 PolarHBondContact O-N 3.43Å
193I98.8Very high97.7Very high2 Ų233 Ų331%0.0116%0.155CC..Hα-helixtrans-67.4-43.6176.3-63.9165.3000110.2K189 I190 I191 L195 K196 L197 L262 K263 W265 Y266K189-I193 HydrophobicContact CB-CD1 4.37Å; K189-I193 VanDerWaalsContact O-CG1 3.24Å; K189-I193 WeakPolarHBondContact O-CG1 3.3Å; K189-I193 PolarHBondContact O-N 3.46Å; I190-I193 HydrophobicContact CD1-CD1 4.3Å; I190-I193 PolarHBondContact O-N 2.92Å; I190-I193 VanDerWaalsContact O-N 3.16Å; I191-I193 VanDerWaalsContact C-N 3.32Å; I191-I193 PolarHBondContact O-N 3.44Å; I193-L195 PolarHBondContact O-N 2.83Å; I193-K196 PolarHBondContact O-N 2.82Å; I193-L197 WeakPolarHBondContact O-CB 3.4Å; I193-L197 PolarHBondContact O-N 3.04Å; I193-L262 HydrophobicContact CG2-CB 4.1Å; I193-L262 HydrophobicContact CG2-CD2 4.2Å; I193-K263 HydrophobicContact CD1-CG 3.96Å; I193-W265 HydrophobicContact CG2-CE3 3.96Å; I193-W265 HydrophobicContact CG2-CZ3 4.01Å; I193-Y266 HydrophobicContact CD1-CG 4.26Å; I193-Y266 HydrophobicContact CG1-CD1 4.24Å; I193-Y266 HydrophobicContact CG1-CD2 3.86Å; I193-Y266 HydrophobicContact CG1-CG 3.7Å
194C98.9Very high97.7Very high0 Ų034.6 Ų34.60%016%0.162CC..Hα-helixtrans-61.1-42.4176.5-67.90000112I190 I191 L197 L198 V288 C291 L292I190-C194 PolarHBondContact O-N 2.8Å; I190-C194 PolarHBondContact O-SG 2.98Å; I191-C194 PolarHBondContact O-N 2.81Å; C194-L197 WeakPolarHBondContact O-CB 3.46Å; C194-L197 PolarHBondContact O-N 2.72Å; C194-L198 PolarHBondContact O-N 3.16Å; C194-V288 HydrophobicContact CB-CG1 4.23Å; C194-C291 HydrophobicContact CB-CB 4.43Å; C194-L292 HydrophobicContact CB-CD2 4.37Å
195L98.8Very high97.6Very high3 Ų340.3 Ų40.32%0.01619%0.188CC..Hα-helixtrans-67.6-39.4174.3-66.4176.7000111.7R114 I137 I191 I193 L197 L198 D199 L292R114-L195 HydrophobicContact CG-CD1 3.81Å; I137-L195 HydrophobicContact CD1-CD1 3.9Å; I137-L195 HydrophobicContact CG1-CD1 4.12Å; I137-L195 HydrophobicContact CG2-CD1 4.04Å; I191-L195 HydrophobicContact CD1-CD1 4.42Å; I191-L195 HydrophobicContact CD1-CG 4.29Å; I191-L195 HydrophobicContact CG1-CD1 4.33Å; I191-L195 WeakPolarHBondContact O-CG 3.2Å; I191-L195 PolarHBondContact O-N 2.66Å; I193-L195 PolarHBondContact O-N 2.83Å; L195-L197 VanDerWaalsContact C-N 3.27Å; L195-L197 PolarHBondContact O-N 2.79Å; L195-L198 PolarHBondContact O-N 2.8Å; L195-D199 PolarHBondContact O-N 3.39Å; L195-L292 HydrophobicContact CD2-CD2 4.01Å
196K98.6Very high97.5Very high75 Ų7546 Ų4633%0.32622%0.223SC..Hα-helixtrans-63.6-33.6175.8-175.258.7173.2175.50112.5D192 I193 D199 K200 Y266D192-K196 WeakPolarHBondContact O-CB 3.33Å; D192-K196 PolarHBondContact O-N 3.43Å; I193-K196 PolarHBondContact O-N 2.82Å; K196-D199 CarbonylContact O-C 3.58Å; K196-D199 PolarHBondContact O-N 2.94Å; K196-K200 WeakPolarHBondContact O-CG 3.24Å; K196-K200 PolarHBondContact O-N 3.35Å; K196-Y266 HydrophobicContact CB-CD2 4.47Å; K196-Y266 HydrophobicContact CB-CE2 4.2Å; K196-Y266 HydrophobicContact CG-CD2 4.25Å; K196-Y266 HydrophobicContact CG-CE2 3.98Å
197L98.7Very high97.5Very high0 Ų049 Ų490%024%0.24CC..Hα-helixtrans-61.2-42.9175.6179.5159.8000111.3I193 C194 L195 D199 K200 V225 M228 I229 V237 W265 V288I193-L197 WeakPolarHBondContact O-CB 3.4Å; I193-L197 PolarHBondContact O-N 3.04Å; C194-L197 WeakPolarHBondContact O-CB 3.46Å; C194-L197 PolarHBondContact O-N 2.72Å; L195-L197 VanDerWaalsContact C-N 3.27Å; L195-L197 PolarHBondContact O-N 2.79Å; L197-D199 VanDerWaalsContact C-N 3.3Å; L197-D199 PolarHBondContact O-N 2.77Å; L197-K200 PolarHBondContact O-N 3.4Å; L197-K200 VanDerWaalsContact O-N 3.08Å; L197-V225 HydrophobicContact CD2-CG2 4.24Å; L197-M228 HydrophobicContact CD1-CB 4.49Å; L197-M228 HydrophobicContact CD2-CB 3.43Å; L197-M228 VanDerWaalsContact CD2-CB 3.43Å; L197-M228 HydrophobicContact CD2-CG 3.89Å; L197-M228 HydrophobicContact CG-CB 3.9Å; L197-M228 HydrophobicContact CG-CE 4.12Å; L197-M228 HydrophobicContact CG-CG 4.42Å; L197-I229 HydrophobicContact CD1-CD1 3.93Å; L197-V237 HydrophobicContact CD1-CG2 3.55Å; L197-V237 HydrophobicContact CG-CG2 4.46Å; L197-W265 HydrophobicContact CB-CH2 4.09Å; L197-W265 HydrophobicContact CB-CZ3 4.23Å; L197-V288 HydrophobicContact CD1-CG2 4.11Å
198L98.7Very high97.6Very high2 Ų249.8 Ų49.81%0.0125%0.246CC..Hα-helixtrans-61.5-39.7174.1-59.7178.4000111.8C194 L195 K200 S201 R215 V221 V224 V225 L292C194-L198 PolarHBondContact O-N 3.16Å; L195-L198 PolarHBondContact O-N 2.8Å; L198-K200 PolarHBondContact O-N 2.84Å; L198-K200 VanDerWaalsContact O-N 3.16Å; L198-S201 PolarHBondContact O-N 2.6Å; L198-S201 PolarHBondContact O-OG 2.96Å; L198-R215 PolarHBondContact O-NH2 2.72Å; L198-V221 HydrophobicContact CD2-CG1 4.26Å; L198-V224 HydrophobicContact CD2-CG1 3.97Å; L198-V225 HydrophobicContact CD2-CG2 3.74Å; L198-L292 HydrophobicContact CD1-CD1 4.24Å; L198-L292 HydrophobicContact CD1-CD2 4.36Å; L198-L292 HydrophobicContact CD2-CD1 4.49Å
199D97.9Very high97.7Very high36 Ų3644.6 Ų44.619%0.19323%0.225CC..THydrogen-bonded Turntrans-73.3-0.1177.3-56.1-21.3000113.8L195 K196 L197 F204 R215L195-D199 PolarHBondContact O-N 3.39Å; K196-D199 CarbonylContact O-C 3.58Å; K196-D199 PolarHBondContact O-N 2.94Å; L197-D199 VanDerWaalsContact C-N 3.3Å; L197-D199 PolarHBondContact O-N 2.77Å; D199-F204 HydrophobicContact CB-CD1 4.18Å; D199-F204 HydrophobicContact CB-CE1 4.04Å; D199-F204 HydrophobicContact CB-CG 4.5Å; D199-F204 HydrophobicContact CB-CZ 4.21Å; D199-F204 WeakPolarHBondContact O-CD1 3.26Å; D199-R215 IonicContact OD1-CZ 2.66Å; D199-R215 VanDerWaalsContact OD1-CZ 3.26Å; D199-R215 IonicContact OD1-NH1 3.82Å; D199-R215 PolarHBondContact OD1-NH1 2.99Å; D199-R215 IonicContact OD1-NH2 2.68Å; D199-R215 PolarHBondContact OD1-NH2 3.33Å
200K97.8Very high97.8Very high73 Ų7341.8 Ų41.832%0.31722%0.217SC..THydrogen-bonded Turntrans-108.7-4.2176.6-74.8-65-171.3176.50113.4K196 L197 L198 Q205 M228 W265 C270K196-K200 WeakPolarHBondContact O-CG 3.24Å; K196-K200 PolarHBondContact O-N 3.35Å; L197-K200 PolarHBondContact O-N 3.4Å; L197-K200 VanDerWaalsContact O-N 3.08Å; L198-K200 PolarHBondContact O-N 2.84Å; L198-K200 VanDerWaalsContact O-N 3.16Å; K200-Q205 PolarHBondContact O-NE2 2.96Å; K200-M228 HydrophobicContact CB-CE 3.59Å; K200-M228 HydrophobicContact CB-SD 4.45Å; K200-W265 HydrophobicContact CB-CH2 4.37Å; K200-W265 HydrophobicContact CB-CZ2 4.38Å; K200-W265 HydrophobicContact CG-CH2 4.12Å; K200-W265 HydrophobicContact CG-CZ2 4.3Å; K200-C270 HydrophobicContact CG-CB 4.47Å
201S97.5Very high97.8Very high0 Ų041.9 Ų41.90%022%0.218CC..SBendtrans-60.8152176.275.80000112.4L198 H203 F204 Q205 D211 M228 D234L198-S201 PolarHBondContact O-N 2.6Å; L198-S201 PolarHBondContact O-OG 2.96Å; S201-H203 PolarHBondContact O-N 2.85Å; S201-F204 PolarHBondContact O-N 2.73Å; S201-F204 WeakPolarHBondContact OG-CB 3.38Å; S201-F204 PolarHBondContact OG-N 2.98Å; S201-Q205 WeakPolarHBondContact O-CG 3.4Å; S201-Q205 PolarHBondContact O-N 3.34Å; S201-D211 PolarHBondContact OG-OD1 2.83Å; S201-M228 WeakPolarHBondContact CA-SD 3.42Å; S201-D234 WeakPolarHBondContact CA-OD2 3.48Å
202L95.9Very high97.8Very high67 Ų6741.5 Ų41.535%0.35122%0.216SC..Hα-helixtrans-58-34.1170.9-77.2177.6000111.7Q205 T206 D233 D234L202-Q205 PolarHBondContact O-N 2.83Å; L202-T206 WeakPolarHBondContact O-CB 3.33Å; L202-T206 PolarHBondContact O-N 2.9Å; L202-T206 PolarHBondContact O-OG1 2.83Å; L202-D233 HydrophobicContact CD1-CB 4.21Å; L202-D234 WeakPolarHBondContact CD1-OD1 3.34Å; L202-D234 HydrophobicContact CG-CB 4.25Å; L202-D234 WeakPolarHBondContact CG-OD1 3.45Å; L202-D234 PolarHBondContact N-OD2 2.96Å
203H96Very high97.8Very high99 Ų9940 Ų4046%0.45821%0.212SC..Hα-helixtrans-61.9-48.5177-67.1-67.3000112.2S201 T206 D207 D211 Y220S201-H203 PolarHBondContact O-N 2.85Å; H203-T206 PolarHBondContact O-N 3.37Å; H203-D207 CarbonylContact O-C 3.55Å; H203-D207 PolarHBondContact O-N 2.89Å; H203-D211 HydrophobicContact CB-CB 4.43Å; H203-Y220 VanDerWaalsContact CB-OH 3.24Å; H203-Y220 WeakPolarHBondContact CB-OH 3.43Å
204F97.6Very high97.8Very high39 Ų3943.6 Ų43.617%0.17123%0.231CC..Hα-helixtrans-65.3-39.6177.2-177.5-91.8000112.1P65 D199 S201 T206 P208 D211P65-F204 HydrophobicContact CG-CE2 4.19Å; P65-F204 HydrophobicContact CG-CZ 4.02Å; D199-F204 HydrophobicContact CB-CD1 4.18Å; D199-F204 HydrophobicContact CB-CE1 4.04Å; D199-F204 HydrophobicContact CB-CG 4.5Å; D199-F204 HydrophobicContact CB-CZ 4.21Å; D199-F204 WeakPolarHBondContact O-CD1 3.26Å; S201-F204 PolarHBondContact O-N 2.73Å; S201-F204 WeakPolarHBondContact OG-CB 3.38Å; S201-F204 PolarHBondContact OG-N 2.98Å; F204-T206 PolarHBondContact O-N 3.38Å; F204-P208 HydrophobicContact CD1-CB 4.44Å; F204-P208 HydrophobicContact CD2-CB 3.83Å; F204-P208 HydrophobicContact CE1-CB 4.26Å; F204-P208 HydrophobicContact CE2-CB 3.64Å; F204-P208 HydrophobicContact CG-CB 4.26Å; F204-P208 HydrophobicContact CZ-CB 3.88Å; F204-P208 WeakPolarHBondContact O-CA 3.46Å; F204-P208 WeakPolarHBondContact O-CB 3.47Å; F204-P208 VanDerWaalsContact O-CD 3.32Å; F204-P208 WeakPolarHBondContact O-CD 3.24Å; F204-D211 HydrophobicContact CB-CB 4.18Å; F204-D211 HydrophobicContact CD2-CB 4.35Å
205Q96.6Very high97.8Very high119 Ų11944.1 Ų44.156%0.55623%0.233SC*.Hα-helixtrans-65.5-30.7177.9-68.8-177.658.600112.4K200 S201 L202K200-Q205 PolarHBondContact O-NE2 2.96Å; S201-Q205 WeakPolarHBondContact O-CG 3.4Å; S201-Q205 PolarHBondContact O-N 3.34Å; L202-Q205 PolarHBondContact O-N 2.83Å
206T96.8Very high97.8Very high119 Ų11944.7 Ų44.773%0.7324%0.239SC*.Hα-helixtrans-83.5-50.4-179.3-56.30000112.1L202 H203 F204L202-T206 WeakPolarHBondContact O-CB 3.33Å; L202-T206 PolarHBondContact O-N 2.9Å; L202-T206 PolarHBondContact O-OG1 2.83Å; H203-T206 PolarHBondContact O-N 3.37Å; F204-T206 PolarHBondContact O-N 3.38Å
207D97.7Very high97.8Very high70 Ų7043.2 Ų43.237%0.37424%0.238SC..  trans-144.988.1-179.4-175.7-9.7000110.1H203 A209 T210 D211H203-D207 CarbonylContact O-C 3.55Å; H203-D207 PolarHBondContact O-N 2.89Å; D207-A209 VanDerWaalsContact C-N 3.27Å; D207-A209 PolarHBondContact O-N 3.21Å; D207-A209 PolarHBondContact OD1-N 2.91Å; D207-T210 VanDerWaalsContact CG-CB 3.47Å; D207-T210 VanDerWaalsContact CG-OG1 3.24Å; D207-T210 PolarHBondContact O-N 3.45Å; D207-T210 PolarHBondContact OD1-N 2.88Å; D207-T210 VanDerWaalsContact OD1-N 3.1Å; D207-T210 PolarHBondContact OD1-OG1 2.98Å; D207-T210 WeakPolarHBondContact OD2-CB 3.17Å; D207-T210 PolarHBondContact OD2-OG1 3.44Å; D207-D211 WeakPolarHBondContact O-CB 3.24Å; D207-D211 PolarHBondContact O-N 3.21Å
208P97.6Very high97.8Very high32 Ų3243.5 Ų43.521%0.20824%0.24CC..Hα-helixtrans-68.2-25.7-175.525.6-33.5000113.2P65 L66 F204 C212P65-P208 HydrophobicContact CG-CB 3.78Å; P65-P208 HydrophobicContact CG-CG 4.34Å; L66-P208 HydrophobicContact CD1-CG 4.35Å; F204-P208 HydrophobicContact CD1-CB 4.44Å; F204-P208 HydrophobicContact CD2-CB 3.83Å; F204-P208 HydrophobicContact CE1-CB 4.26Å; F204-P208 HydrophobicContact CE2-CB 3.64Å; F204-P208 HydrophobicContact CG-CB 4.26Å; F204-P208 HydrophobicContact CZ-CB 3.88Å; F204-P208 WeakPolarHBondContact O-CA 3.46Å; F204-P208 WeakPolarHBondContact O-CB 3.47Å; F204-P208 VanDerWaalsContact O-CD 3.32Å; F204-P208 WeakPolarHBondContact O-CD 3.24Å; P208-C212 WeakPolarHBondContact O-CB 3.4Å; P208-C212 PolarHBondContact O-N 2.91Å; P208-C212 VanDerWaalsContact O-N 3.15Å; P208-C212 PolarHBondContact O-SG 3.02Å
209A97.5Very high97.8Very high17 Ų1744 Ų4414%0.1424%0.244CC..Hα-helixtrans-68.8-48.8177.800000110.3L66 L71 D207 A213L66-A209 HydrophobicContact CB-CB 4.04Å; L66-A209 HydrophobicContact CD1-CB 4.1Å; L71-A209 HydrophobicContact CD1-CB 4.37Å; D207-A209 VanDerWaalsContact C-N 3.27Å; D207-A209 PolarHBondContact O-N 3.21Å; D207-A209 PolarHBondContact OD1-N 2.91Å; A209-A213 PolarHBondContact O-N 2.95Å; A209-A213 VanDerWaalsContact O-N 3.14Å
210T98.1Very high97.8Very high57 Ų5744.1 Ų44.135%0.3524%0.241SC..Hα-helixtrans-68-43.6178.5-61.20000111.9D207 C212 A213 L214D207-T210 VanDerWaalsContact CG-CB 3.47Å; D207-T210 VanDerWaalsContact CG-OG1 3.24Å; D207-T210 PolarHBondContact O-N 3.45Å; D207-T210 PolarHBondContact OD1-N 2.88Å; D207-T210 VanDerWaalsContact OD1-N 3.1Å; D207-T210 PolarHBondContact OD1-OG1 2.98Å; D207-T210 WeakPolarHBondContact OD2-CB 3.17Å; D207-T210 PolarHBondContact OD2-OG1 3.44Å; T210-C212 PolarHBondContact O-N 3Å; T210-A213 PolarHBondContact O-N 2.9Å; T210-L214 HydrophobicContact CG2-CD1 3.8Å; T210-L214 HydrophobicContact CG2-CG 4.24Å; T210-L214 VanDerWaalsContact O-CG 3.31Å; T210-L214 WeakPolarHBondContact O-CG 3.19Å; T210-L214 PolarHBondContact O-N 3.18Å
211D98.6Very high97.9Very high2 Ų240.7 Ų40.71%0.01123%0.227CC..Hα-helixtrans-56.1-51.7176.6173.498.4000111.1S201 H203 F204 D207 A213 L214 R215 Y220S201-D211 PolarHBondContact OG-OD1 2.83Å; H203-D211 HydrophobicContact CB-CB 4.43Å; F204-D211 HydrophobicContact CB-CB 4.18Å; F204-D211 HydrophobicContact CD2-CB 4.35Å; D207-D211 WeakPolarHBondContact O-CB 3.24Å; D207-D211 PolarHBondContact O-N 3.21Å; D211-A213 VanDerWaalsContact C-N 3.31Å; D211-A213 PolarHBondContact O-N 3.49Å; D211-L214 PolarHBondContact O-N 3.36Å; D211-L214 VanDerWaalsContact O-N 3.1Å; D211-R215 WeakPolarHBondContact O-CG 3.4Å; D211-R215 PolarHBondContact O-N 2.81Å; D211-R215 VanDerWaalsContact O-N 3.15Å; D211-R215 IonicContact OD2-CZ 3.4Å; D211-R215 IonicContact OD2-NE 3.77Å; D211-R215 PolarHBondContact OD2-NE 3.24Å; D211-R215 IonicContact OD2-NH2 3.42Å; D211-R215 PolarHBondContact OD2-NH2 3.13Å; D211-Y220 PolarHBondContact OD1-OH 2.95Å
212C98.5Very high97.9Very high3 Ų340.7 Ų40.72%0.0223%0.227CC..Hα-helixtrans-60.3-37.9178.6-77.60000113.1T73 A111 P208 T210 L214 R215T73-C212 HydrophobicContact CG2-CB 4.1Å; A111-C212 VanDerWaalsContact CB-O 3.31Å; A111-C212 WeakPolarHBondContact CB-O 3.49Å; P208-C212 WeakPolarHBondContact O-CB 3.4Å; P208-C212 PolarHBondContact O-N 2.91Å; P208-C212 VanDerWaalsContact O-N 3.15Å; P208-C212 PolarHBondContact O-SG 3.02Å; T210-C212 PolarHBondContact O-N 3Å; C212-L214 VanDerWaalsContact C-N 3.35Å; C212-R215 WeakPolarHBondContact O-CB 3.03Å; C212-R215 PolarHBondContact O-N 3.48Å
213A98.1Very high98Very high26 Ų2639.3 Ų39.322%0.21522%0.217CC..Hα-helixtrans-65.2-39175.500000112.2L71 T73 A209 T210 D211 R215L71-A213 HydrophobicContact CB-CB 3.88Å; T73-A213 HydrophobicContact CG2-CB 4.03Å; A209-A213 PolarHBondContact O-N 2.95Å; A209-A213 VanDerWaalsContact O-N 3.14Å; T210-A213 PolarHBondContact O-N 2.9Å; D211-A213 VanDerWaalsContact C-N 3.31Å; D211-A213 PolarHBondContact O-N 3.49Å; A213-R215 VanDerWaalsContact C-N 3.27Å; A213-R215 PolarHBondContact O-N 3.07Å
214L98.5Very high98.2Very high76 Ų7634.7 Ų34.740%0.39820%0.196SC..Hα-helixtrans-74.3-13.6179.8-68.4175000113.7T210 D211 C212 G216 S217 Y220T210-L214 HydrophobicContact CG2-CD1 3.8Å; T210-L214 HydrophobicContact CG2-CG 4.24Å; T210-L214 VanDerWaalsContact O-CG 3.31Å; T210-L214 WeakPolarHBondContact O-CG 3.19Å; T210-L214 PolarHBondContact O-N 3.18Å; D211-L214 PolarHBondContact O-N 3.36Å; D211-L214 VanDerWaalsContact O-N 3.1Å; C212-L214 VanDerWaalsContact C-N 3.35Å; L214-G216 PolarHBondContact O-N 2.82Å; L214-S217 WeakPolarHBondContact O-CB 3.47Å; L214-S217 PolarHBondContact O-N 3.28Å; L214-Y220 HydrophobicContact CB-CD1 3.47Å; L214-Y220 VanDerWaalsContact CB-CD1 3.47Å; L214-Y220 HydrophobicContact CB-CD2 4.01Å; L214-Y220 HydrophobicContact CB-CE1 3.51Å; L214-Y220 HydrophobicContact CB-CE2 4.07Å; L214-Y220 HydrophobicContact CB-CG 3.71Å; L214-Y220 HydrophobicContact CD1-CD2 3.98Å; L214-Y220 HydrophobicContact CD1-CE1 4.46Å; L214-Y220 HydrophobicContact CD1-CE2 3.63Å; L214-Y220 WeakPolarHBondContact O-CD1 3.37Å
215R98.8Very high98.2Very high12 Ų1232.9 Ų32.95%0.04519%0.187CC..THydrogen-bonded Turntrans-62.7-5.9173.9-67.5175.6-165.9-166.41113.9A111 V112 L198 D199 D211 C212 A213 S217 V221A111-R215 HydrophobicContact CB-CB 4.25Å; V112-R215 HydrophobicContact CG2-CB 4.3Å; V112-R215 PolarHBondContact N-O 2.75Å; L198-R215 PolarHBondContact O-NH2 2.72Å; D199-R215 IonicContact OD1-CZ 2.66Å; D199-R215 VanDerWaalsContact OD1-CZ 3.26Å; D199-R215 IonicContact OD1-NH1 3.82Å; D199-R215 PolarHBondContact OD1-NH1 2.99Å; D199-R215 IonicContact OD1-NH2 2.68Å; D199-R215 PolarHBondContact OD1-NH2 3.33Å; D211-R215 WeakPolarHBondContact O-CG 3.4Å; D211-R215 PolarHBondContact O-N 2.81Å; D211-R215 VanDerWaalsContact O-N 3.15Å; D211-R215 IonicContact OD2-CZ 3.4Å; D211-R215 IonicContact OD2-NE 3.77Å; D211-R215 PolarHBondContact OD2-NE 3.24Å; D211-R215 IonicContact OD2-NH2 3.42Å; D211-R215 PolarHBondContact OD2-NH2 3.13Å; C212-R215 WeakPolarHBondContact O-CB 3.03Å; C212-R215 PolarHBondContact O-N 3.48Å; A213-R215 VanDerWaalsContact C-N 3.27Å; A213-R215 PolarHBondContact O-N 3.07Å; R215-S217 VanDerWaalsContact C-N 3.26Å; R215-V221 HydrophobicContact CB-CG2 4.22Å; R215-V221 HydrophobicContact CG-CG2 4.39Å
216G98.1Very high98.3Very high14 Ų1427.2 Ų27.214%0.14416%0.161CC..THydrogen-bonded Turntrans-72.6-15.6167.400000114R35 L214R35-G216 PolarHBondContact NH1-O 2.81Å; L214-G216 PolarHBondContact O-N 2.82Å
217S98.7Very high98.4Very high45 Ų4521.9 Ų21.932%0.31513%0.129SC..  trans-99.2120-178.6174.90000111.4L214 R215 V219 Y220 V221L214-S217 WeakPolarHBondContact O-CB 3.47Å; L214-S217 PolarHBondContact O-N 3.28Å; R215-S217 VanDerWaalsContact C-N 3.26Å; S217-V219 PolarHBondContact O-N 3.06Å; S217-V219 PolarHBondContact OG-N 3.29Å; S217-Y220 PolarHBondContact O-N 3.09Å; S217-Y220 PolarHBondContact OG-N 3.2Å; S217-V221 WeakPolarHBondContact O-CG2 3.41Å; S217-V221 PolarHBondContact O-N 3.45Å
218P98.8Very high98.4Very high6 Ų618.6 Ų18.64%0.03911%0.112CC..Hα-helixtrans-65.4-28.5174.728.1-34.4000111.9F140 A148 V149 S222 I294 M344F140-P218 HydrophobicContact CD1-CB 4.41Å; F140-P218 HydrophobicContact CE1-CB 3.85Å; F140-P218 HydrophobicContact CE1-CG 4.35Å; F140-P218 HydrophobicContact CZ-CB 4.12Å; A148-P218 HydrophobicContact CB-CG 3.73Å; V149-P218 HydrophobicContact CG1-CB 3.61Å; V149-P218 HydrophobicContact CG1-CG 3.95Å; P218-S222 WeakPolarHBondContact O-CB 3.45Å; P218-S222 PolarHBondContact O-N 3.32Å; P218-S222 PolarHBondContact O-OG 3.41Å; P218-I294 HydrophobicContact CB-CD1 4.18Å; P218-M344 HydrophobicContact CB-CB 4.23Å; P218-M344 HydrophobicContact CB-SD 4.18Å; P218-M344 HydrophobicContact CG-CB 4.03Å; P218-M344 HydrophobicContact CG-SD 4.43Å
219V98.7Very high98.5Very high13 Ų1317 Ų178%0.07910%0.102CC..Hα-helixtrans-62.1-46.9174171.40000110.4S217 S222 R223 M344 P375 Y390S217-V219 PolarHBondContact O-N 3.06Å; S217-V219 PolarHBondContact OG-N 3.29Å; V219-S222 PolarHBondContact O-N 3.33Å; V219-R223 PolarHBondContact O-N 2.84Å; V219-M344 HydrophobicContact CB-SD 4.48Å; V219-M344 HydrophobicContact CG2-SD 3.78Å; V219-P375 HydrophobicContact CB-CG 4.42Å; V219-P375 HydrophobicContact CG1-CG 3.8Å; V219-P375 HydrophobicContact CG2-CG 4.49Å; V219-Y390 HydrophobicContact CG1-CE2 3.87Å
220Y98.6Very high98.5Very high38 Ų3816.3 Ų16.315%0.14910%0.095CC..Hα-helixtrans-66.2-52.8179.2178.2-101.7000111.7H203 D211 L214 S217 S222 R223 V224H203-Y220 VanDerWaalsContact CB-OH 3.24Å; H203-Y220 WeakPolarHBondContact CB-OH 3.43Å; D211-Y220 PolarHBondContact OD1-OH 2.95Å; L214-Y220 HydrophobicContact CB-CD1 3.47Å; L214-Y220 VanDerWaalsContact CB-CD1 3.47Å; L214-Y220 HydrophobicContact CB-CD2 4.01Å; L214-Y220 HydrophobicContact CB-CE1 3.51Å; L214-Y220 HydrophobicContact CB-CE2 4.07Å; L214-Y220 HydrophobicContact CB-CG 3.71Å; L214-Y220 HydrophobicContact CD1-CD2 3.98Å; L214-Y220 HydrophobicContact CD1-CE1 4.46Å; L214-Y220 HydrophobicContact CD1-CE2 3.63Å; L214-Y220 WeakPolarHBondContact O-CD1 3.37Å; S217-Y220 PolarHBondContact O-N 3.09Å; S217-Y220 PolarHBondContact OG-N 3.2Å; Y220-S222 PolarHBondContact O-N 2.85Å; Y220-R223 PolarHBondContact O-N 2.88Å; Y220-R223 VanDerWaalsContact O-N 3.09Å; Y220-V224 HydrophobicContact CD1-CG2 4.1Å; Y220-V224 HydrophobicContact CD2-CG2 4.47Å; Y220-V224 HydrophobicContact CE1-CG2 3.67Å; Y220-V224 HydrophobicContact CE2-CG2 4.07Å; Y220-V224 HydrophobicContact CG-CG2 4.49Å; Y220-V224 WeakPolarHBondContact O-CG2 3.3Å; Y220-V224 PolarHBondContact O-N 3.48Å
221V98.8Very high98.4Very high1 Ų114.2 Ų14.21%0.0068%0.083CC..Hα-helixtrans-56.8-39.3178.4173.20000110.5V112 F140 L198 R215 S217 R223 V224 V225 L292 I294V112-V221 HydrophobicContact CG2-CG2 4.43Å; F140-V221 HydrophobicContact CE2-CB 4.17Å; F140-V221 HydrophobicContact CE2-CG1 4.13Å; F140-V221 HydrophobicContact CE2-CG2 4.04Å; F140-V221 HydrophobicContact CZ-CB 4.22Å; F140-V221 HydrophobicContact CZ-CG2 3.9Å; L198-V221 HydrophobicContact CD2-CG1 4.26Å; R215-V221 HydrophobicContact CB-CG2 4.22Å; R215-V221 HydrophobicContact CG-CG2 4.39Å; S217-V221 WeakPolarHBondContact O-CG2 3.41Å; S217-V221 PolarHBondContact O-N 3.45Å; V221-R223 PolarHBondContact O-N 3.03Å; V221-V224 PolarHBondContact O-N 3.11Å; V221-V225 HydrophobicContact CG1-CG2 4.16Å; V221-V225 WeakPolarHBondContact O-CB 3.42Å; V221-V225 VanDerWaalsContact O-CG2 3.32Å; V221-V225 WeakPolarHBondContact O-CG2 3.12Å; V221-V225 PolarHBondContact O-N 2.85Å; V221-L292 HydrophobicContact CG1-CD1 3.87Å; V221-I294 HydrophobicContact CG1-CD1 4.22Å
222S98.6Very high98.2Very high0 Ų018 Ų180%010%0.103CC..Hα-helixtrans-64.1-41.4180-60.50000112.4P218 V219 Y220 C226 M344 L359P218-S222 WeakPolarHBondContact O-CB 3.45Å; P218-S222 PolarHBondContact O-N 3.32Å; P218-S222 PolarHBondContact O-OG 3.41Å; V219-S222 PolarHBondContact O-N 3.33Å; Y220-S222 PolarHBondContact O-N 2.85Å; S222-C226 VanDerWaalsContact O-CB 3.22Å; S222-C226 WeakPolarHBondContact O-CB 3.17Å; S222-C226 PolarHBondContact O-N 3.31Å; S222-M344 VanDerWaalsContact OG-CE 3.29Å; S222-M344 WeakPolarHBondContact OG-CE 3.36Å; S222-L359 WeakPolarHBondContact O-CD2 3.37Å
223R98.2Very high97.9Very high37 Ų3720.4 Ų20.414%0.1412%0.116CC..Hα-helixtrans-65.9-44.2174.8-71.7-169.863.593.7-6.9112.5V219 Y220 V221 V225 C226 A227 S367 C372 G374 D391V219-R223 PolarHBondContact O-N 2.84Å; Y220-R223 PolarHBondContact O-N 2.88Å; Y220-R223 VanDerWaalsContact O-N 3.09Å; V221-R223 PolarHBondContact O-N 3.03Å; R223-V225 PolarHBondContact O-N 2.81Å; R223-C226 WeakPolarHBondContact O-CB 3.43Å; R223-C226 PolarHBondContact O-N 3.17Å; R223-A227 PolarHBondContact O-N 3.49Å; R223-S367 PolarHBondContact NH2-OG 3.36Å; R223-C372 PolarHBondContact O-SG 3.31Å; R223-G374 VanDerWaalsContact CG-O 3.3Å; R223-G374 WeakPolarHBondContact CG-O 3.36Å; R223-G374 PolarHBondContact NH1-O 2.98Å; R223-D391 IonicContact NH1-OD2 3.69Å; R223-D391 PolarHBondContact NH1-OD2 2.73Å
224V98.6Very high97.1Very high3 Ų319.8 Ų19.82%0.01811%0.109CC..Hα-helixtrans-59.3-48.5177.3171.10000110.7L198 Y220 V221 A227 M228L198-V224 HydrophobicContact CD2-CG1 3.97Å; Y220-V224 HydrophobicContact CD1-CG2 4.1Å; Y220-V224 HydrophobicContact CD2-CG2 4.47Å; Y220-V224 HydrophobicContact CE1-CG2 3.67Å; Y220-V224 HydrophobicContact CE2-CG2 4.07Å; Y220-V224 HydrophobicContact CG-CG2 4.49Å; Y220-V224 WeakPolarHBondContact O-CG2 3.3Å; Y220-V224 PolarHBondContact O-N 3.48Å; V221-V224 PolarHBondContact O-N 3.11Å; V224-A227 PolarHBondContact O-N 3.09Å; V224-M228 HydrophobicContact CG1-CG 4.42Å; V224-M228 VanDerWaalsContact O-CB 3.31Å; V224-M228 WeakPolarHBondContact O-CB 3.49Å; V224-M228 WeakPolarHBondContact O-CG 3.45Å; V224-M228 PolarHBondContact O-N 2.81Å
225V98.8Very high96.7Very high0 Ų019.7 Ų19.70%011%0.109CC..Hα-helixtrans-62.8-44.8177.8170.80000110.4L197 L198 V221 R223 A227 M228 I229 M285 V288 M289 L292L197-V225 HydrophobicContact CD2-CG2 4.24Å; L198-V225 HydrophobicContact CD2-CG2 3.74Å; V221-V225 HydrophobicContact CG1-CG2 4.16Å; V221-V225 WeakPolarHBondContact O-CB 3.42Å; V221-V225 VanDerWaalsContact O-CG2 3.32Å; V221-V225 WeakPolarHBondContact O-CG2 3.12Å; V221-V225 PolarHBondContact O-N 2.85Å; R223-V225 PolarHBondContact O-N 2.81Å; V225-A227 PolarHBondContact O-N 2.96Å; V225-M228 PolarHBondContact O-N 2.94Å; V225-M228 VanDerWaalsContact O-N 3.1Å; V225-I229 HydrophobicContact CG1-CD1 3.88Å; V225-I229 HydrophobicContact CG1-CG1 4.11Å; V225-I229 VanDerWaalsContact O-CG1 3.22Å; V225-I229 WeakPolarHBondContact O-CG1 3.3Å; V225-I229 PolarHBondContact O-N 2.64Å; V225-M285 HydrophobicContact CG1-CG 4.2Å; V225-V288 HydrophobicContact CG1-CB 4.05Å; V225-V288 HydrophobicContact CG1-CG1 3.72Å; V225-V288 HydrophobicContact CG2-CG1 3.89Å; V225-M289 HydrophobicContact CB-CE 3.76Å; V225-M289 HydrophobicContact CB-SD 4.16Å; V225-M289 HydrophobicContact CG1-CE 3.72Å; V225-M289 HydrophobicContact CG1-SD 4.06Å; V225-M289 HydrophobicContact CG2-SD 4.34Å; V225-L292 HydrophobicContact CG2-CD1 4.15Å
226C98.4Very high96.6Very high0 Ų019.1 Ų19.10%011%0.107CC..Hα-helixtrans-51.8-50.9177.8-169.90000112.3S222 R223 M285 L359 D360 C373S222-C226 VanDerWaalsContact O-CB 3.22Å; S222-C226 WeakPolarHBondContact O-CB 3.17Å; S222-C226 PolarHBondContact O-N 3.31Å; R223-C226 WeakPolarHBondContact O-CB 3.43Å; R223-C226 PolarHBondContact O-N 3.17Å; C226-M285 HydrophobicContact CB-CE 3.63Å; C226-L359 HydrophobicContact CB-CD2 4.01Å; C226-D360 PolarHBondContact SG-O 2.86Å; C226-C373 PolarHBondContact SG-O 3.23Å; C226-C373 VanDerWaalsContact SG-O 3.35Å
227A98.1Very high96.6Very high8 Ų818.4 Ų18.47%0.06610%0.1CC..Hα-helixtrans-62.1-45.8175.500000112R223 V224 V225 I229 N230 V370 C372R223-A227 PolarHBondContact O-N 3.49Å; V224-A227 PolarHBondContact O-N 3.09Å; V225-A227 PolarHBondContact O-N 2.96Å; A227-I229 VanDerWaalsContact C-N 3.29Å; A227-I229 PolarHBondContact O-N 2.81Å; A227-N230 PolarHBondContact O-N 2.72Å; A227-N230 PolarHBondContact O-ND2 3.19Å; A227-N230 VanDerWaalsContact O-O 3.12Å; A227-V370 HydrophobicContact CB-CG1 3.92Å; A227-C372 HydrophobicContact CB-CB 4.05Å
228M98.5Very high96.6Very high0 Ų016.3 Ų16.30%09%0.085CC..Hα-helixtrans-69.1-19.1-176-81.7-61-5600114.9L197 K200 S201 V224 V225 N230 D234 G236 V237 W265L197-M228 HydrophobicContact CD1-CB 4.49Å; L197-M228 HydrophobicContact CD2-CB 3.43Å; L197-M228 VanDerWaalsContact CD2-CB 3.43Å; L197-M228 HydrophobicContact CD2-CG 3.89Å; L197-M228 HydrophobicContact CG-CB 3.9Å; L197-M228 HydrophobicContact CG-CE 4.12Å; L197-M228 HydrophobicContact CG-CG 4.42Å; K200-M228 HydrophobicContact CB-CE 3.59Å; K200-M228 HydrophobicContact CB-SD 4.45Å; S201-M228 WeakPolarHBondContact CA-SD 3.42Å; V224-M228 HydrophobicContact CG1-CG 4.42Å; V224-M228 VanDerWaalsContact O-CB 3.31Å; V224-M228 WeakPolarHBondContact O-CB 3.49Å; V224-M228 WeakPolarHBondContact O-CG 3.45Å; V224-M228 PolarHBondContact O-N 2.81Å; V225-M228 PolarHBondContact O-N 2.94Å; V225-M228 VanDerWaalsContact O-N 3.1Å; M228-N230 VanDerWaalsContact C-N 3.34Å; M228-D234 HydrophobicContact SD-CB 3.4Å; M228-D234 WeakPolarHBondContact SD-CB 3.05Å; M228-D234 VanDerWaalsContact SD-OD2 3.41Å; M228-G236 CarbonylContact O-C 3.6Å; M228-G236 WeakPolarHBondContact O-CA 3.41Å; M228-V237 PolarHBondContact O-N 2.77Å; M228-W265 HydrophobicContact CE-CZ2 4.14Å
229I98.7Very high96.6Very high0 Ų018.3 Ų18.30%010%0.095CC..Hα-helixtrans-70.8-33.8178.1-61.3-36.9000110.6L197 V225 A227 V237 L238 F281 V284 M285 V288 A361L197-I229 HydrophobicContact CD1-CD1 3.93Å; V225-I229 HydrophobicContact CG1-CD1 3.88Å; V225-I229 HydrophobicContact CG1-CG1 4.11Å; V225-I229 VanDerWaalsContact O-CG1 3.22Å; V225-I229 WeakPolarHBondContact O-CG1 3.3Å; V225-I229 PolarHBondContact O-N 2.64Å; A227-I229 VanDerWaalsContact C-N 3.29Å; A227-I229 PolarHBondContact O-N 2.81Å; I229-V237 HydrophobicContact CD1-CG2 4.46Å; I229-V237 PolarHBondContact O-N 3.37Å; I229-L238 HydrophobicContact CG2-CD1 4.37Å; I229-L238 WeakPolarHBondContact O-CB 3.39Å; I229-L238 PolarHBondContact O-N 3.48Å; I229-F281 HydrophobicContact CG2-CB 4.2Å; I229-F281 HydrophobicContact CG2-CD1 3.95Å; I229-F281 WeakPolarHBondContact CG2-O 3.42Å; I229-V284 HydrophobicContact CD1-CG1 4.2Å; I229-V284 HydrophobicContact CG2-CB 4.3Å; I229-V284 HydrophobicContact CG2-CG1 4.26Å; I229-M285 HydrophobicContact CG1-CB 3.8Å; I229-M285 HydrophobicContact CG1-CG 4.15Å; I229-V288 HydrophobicContact CD1-CG2 4.14Å; I229-A361 HydrophobicContact CB-CB 3.77Å; I229-A361 HydrophobicContact CG1-CB 4.25Å; I229-A361 HydrophobicContact CG2-CB 4.01Å
230N97.6Very high96.5Very high1 Ų118.7 Ų18.71%0.00510%0.102CC..BIsolated β-bridgetrans-96.8159.9175.377.381.1000112.4A227 M228 N232 G236 L238 F281 A361 P363 Y371A227-N230 PolarHBondContact O-N 2.72Å; A227-N230 PolarHBondContact O-ND2 3.19Å; A227-N230 VanDerWaalsContact O-O 3.12Å; M228-N230 VanDerWaalsContact C-N 3.34Å; N230-N232 PolarHBondContact OD1-N 3.15Å; N230-N232 PolarHBondContact OD1-ND2 3.32Å; N230-G236 VanDerWaalsContact O-CA 3.29Å; N230-G236 WeakPolarHBondContact O-CA 3.35Å; N230-G236 PolarHBondContact O-N 3.21Å; N230-L238 CarbonylContact C-O 3.46Å; N230-L238 WeakPolarHBondContact CA-O 3.33Å; N230-F281 HydrophobicContact CB-CD1 4.07Å; N230-F281 HydrophobicContact CB-CE1 3.69Å; N230-A361 WeakPolarHBondContact CB-O 3.45Å; N230-A361 PolarHBondContact ND2-O 3.45Å; N230-P363 HydrophobicContact CB-CB 4.44Å; N230-P363 HydrophobicContact CB-CG 4.31Å; N230-Y371 PolarHBondContact ND2-O 3.04Å
231S96.3Very high96.2Very high14 Ų1417.9 Ų17.910%0.09810%0.1CC..SBendtrans-97.66.3-171.879.30000115.7L238 N239S231-L238 WeakPolarHBondContact CB-O 3.34Å; S231-L238 PolarHBondContact N-O 3.06Å; S231-L238 PolarHBondContact OG-O 2.86Å; S231-N239 PolarHBondContact OG-ND2 2.85Å
232N94.1Very high95.7Very high80 Ų8020.5 Ų20.543%0.42811%0.11SC..SBendtrans-71.2-42.1-165.1-67-84.3000112.9N230 P363 Y371N230-N232 PolarHBondContact OD1-N 3.15Å; N230-N232 PolarHBondContact OD1-ND2 3.32Å; N232-P363 WeakPolarHBondContact ND2-CB 3.33Å; N232-P363 VanDerWaalsContact ND2-CG 3.27Å; N232-P363 WeakPolarHBondContact ND2-CG 3.36Å; N232-Y371 HydrophobicContact CB-CD2 3.41Å; N232-Y371 VanDerWaalsContact CB-CD2 3.41Å; N232-Y371 HydrophobicContact CB-CE2 3.91Å; N232-Y371 HydrophobicContact CB-CG 4.17Å
233D92.4Very high95.2Very high55 Ų5524 Ų2429%0.29414%0.135SC..SBendtrans-110.7-59.6-175.5-51.5-57.6000111L202 N235 V370 Y371L202-D233 HydrophobicContact CD1-CB 4.21Å; D233-N235 PolarHBondContact O-N 3.27Å; D233-V370 HydrophobicContact CB-CG1 4.3Å; D233-Y371 WeakPolarHBondContact OD2-CB 3.43Å; D233-Y371 WeakPolarHBondContact OD2-CD2 3.46Å; D233-Y371 PolarHBondContact OD2-N 3.14Å
234D82.4Confident94.6Very high12 Ų1224.9 Ų24.96%0.06414%0.141CC..SBendtrans-78.92.8-173.4-65.925.3000113.8S201 L202 M228 G236S201-D234 WeakPolarHBondContact CA-OD2 3.48Å; L202-D234 WeakPolarHBondContact CD1-OD1 3.34Å; L202-D234 HydrophobicContact CG-CB 4.25Å; L202-D234 WeakPolarHBondContact CG-OD1 3.45Å; L202-D234 PolarHBondContact N-OD2 2.96Å; M228-D234 HydrophobicContact SD-CB 3.4Å; M228-D234 WeakPolarHBondContact SD-CB 3.05Å; M228-D234 VanDerWaalsContact SD-OD2 3.41Å; D234-G236 PolarHBondContact O-N 3.14Å
235N89.9Confident94.2Very high74 Ų7428.9 Ų28.940%0.39616%0.162SC..  trans50.842.8-166.8-167.756.1000111.5D233 P272D233-N235 PolarHBondContact O-N 3.27Å; N235-P272 WeakPolarHBondContact OD1-CD 3.11Å; N235-P272 WeakPolarHBondContact OD1-CG 3.44Å
236G96.5Very high93.9Very high0 Ų029.9 Ų29.90%017%0.166CC..  trans-67.2-156.2-176.100000115.6M228 N230 D234 W265M228-G236 CarbonylContact O-C 3.6Å; M228-G236 WeakPolarHBondContact O-CA 3.41Å; N230-G236 VanDerWaalsContact O-CA 3.29Å; N230-G236 WeakPolarHBondContact O-CA 3.35Å; N230-G236 PolarHBondContact O-N 3.21Å; D234-G236 PolarHBondContact O-N 3.14Å; G236-W265 PolarHBondContact O-NE1 2.88Å
237V98.7Very high93.6Very high0 Ų036 Ų360%020%0.203CC..SBendtrans-71-49.6-162.8-176.10000113.4L197 M228 I229 I261 L262 W265 V273 V284L197-V237 HydrophobicContact CD1-CG2 3.55Å; L197-V237 HydrophobicContact CG-CG2 4.46Å; M228-V237 PolarHBondContact O-N 2.77Å; I229-V237 HydrophobicContact CD1-CG2 4.46Å; I229-V237 PolarHBondContact O-N 3.37Å; V237-I261 HydrophobicContact CG1-CG2 3.87Å; V237-L262 HydrophobicContact CG1-CD2 4.22Å; V237-L262 HydrophobicContact CG2-CD2 4.4Å; V237-W265 HydrophobicContact CB-CG 4.46Å; V237-W265 HydrophobicContact CG1-CB 4.11Å; V237-W265 HydrophobicContact CG1-CG 4.15Å; V237-W265 HydrophobicContact CG2-CD2 4.2Å; V237-W265 HydrophobicContact CG2-CG 4.4Å; V237-V273 PolarHBondContact O-N 2.72Å; V237-V284 HydrophobicContact CG1-CG1 4.27Å
238L98.5Very high93.4Very high0 Ų039.8 Ų39.80%022%0.222CC..EExtended strand (participates in β ladder)trans-120.1136.8-168.7-78.2162.1000112.4I229 N230 S231 I261 V273 V280 F281 V284I229-L238 HydrophobicContact CG2-CD1 4.37Å; I229-L238 WeakPolarHBondContact O-CB 3.39Å; I229-L238 PolarHBondContact O-N 3.48Å; N230-L238 CarbonylContact C-O 3.46Å; N230-L238 WeakPolarHBondContact CA-O 3.33Å; S231-L238 WeakPolarHBondContact CB-O 3.34Å; S231-L238 PolarHBondContact N-O 3.06Å; S231-L238 PolarHBondContact OG-O 2.86Å; L238-I261 HydrophobicContact CD1-CG2 4.46Å; L238-I261 HydrophobicContact CD2-CD1 4.49Å; L238-I261 HydrophobicContact CD2-CG2 3.72Å; L238-I261 HydrophobicContact CG-CG2 4.03Å; L238-V273 HydrophobicContact CD2-CB 4.17Å; L238-V273 HydrophobicContact CD2-CG1 4.32Å; L238-V280 HydrophobicContact CD1-CB 4.41Å; L238-V280 HydrophobicContact CD1-CG1 3.73Å; L238-V280 HydrophobicContact CD2-CG1 4.14Å; L238-F281 HydrophobicContact CB-CD1 3.91Å; L238-F281 HydrophobicContact CB-CE1 3.41Å; L238-F281 VanDerWaalsContact CB-CE1 3.41Å; L238-F281 HydrophobicContact CB-CZ 4.13Å; L238-F281 HydrophobicContact CD1-CD1 3.97Å; L238-F281 HydrophobicContact CD1-CE1 4.28Å; L238-F281 HydrophobicContact CD1-CG 4.46Å; L238-V284 HydrophobicContact CD1-CB 4.32Å; L238-V284 HydrophobicContact CD1-CG2 4.01Å
239N98.1Very high93.3Very high48 Ų4841.4 Ų41.426%0.25724%0.239SC..EExtended strand (participates in β ladder)trans-92.6126.5167.1-168.5-99.6000110.2S231 P272 V273 R274 Y275 G276S231-N239 PolarHBondContact OG-ND2 2.85Å; N239-P272 HydrophobicContact CB-CB 4.23Å; N239-V273 PolarHBondContact N-O 2.92Å; N239-R274 HydrophobicContact CB-CG 4.13Å; N239-Y275 HydrophobicContact CB-CD1 4.24Å; N239-Y275 HydrophobicContact CB-CE1 4.49Å; N239-Y275 CarbonylContact O-C 3.55Å; N239-Y275 WeakPolarHBondContact O-CA 3.07Å; N239-Y275 WeakPolarHBondContact O-CD1 3.23Å; N239-Y275 WeakPolarHBondContact OD1-CD1 3.35Å; N239-Y275 WeakPolarHBondContact OD1-CE1 3.33Å; N239-G276 PolarHBondContact O-N 3.39Å
240G95.9Very high93.1Very high22 Ų2242.6 Ų42.623%0.22725%0.249CC..EExtended strand (participates in β ladder)trans-81.4137.9-178.300000112.9G276G240-G276 WeakPolarHBondContact CA-O 3.41Å
241N93.3Very high92.9Very high20 Ų2043.1 Ų43.111%0.10725%0.252CS..  trans-150.4122.6174.9-174.80.2000112.3S243 N245 Y246 Y275 G276 Q277N241-S243 VanDerWaalsContact OD1-CB 3.32Å; N241-S243 WeakPolarHBondContact OD1-CB 3.49Å; N241-S243 PolarHBondContact OD1-N 2.83Å; N241-S243 PolarHBondContact OD1-OG 3.08Å; N241-N245 PolarHBondContact ND2-O 2.61Å; N241-Y246 HydrophobicContact CB-CD1 4.42Å; N241-Y246 HydrophobicContact CB-CE1 4.1Å; N241-Y246 WeakPolarHBondContact O-CE1 3.12Å; N241-Y275 HydrophobicContact CB-CD1 3.36Å; N241-Y275 HydrophobicContact CB-CD2 4.31Å; N241-Y275 HydrophobicContact CB-CE1 3.82Å; N241-Y275 HydrophobicContact CB-CG 3.63Å; N241-G276 PolarHBondContact N-O 2.98Å; N241-Q277 PolarHBondContact O-NE2 3.29Å
242W89.1Confident92.8Very high56 Ų5642.4 Ų42.421%0.21225%0.247CC..  trans-11612.2179.2-71-100.8000113.2E244 Q277 F281 W334 T362 H550W242-E244 VanDerWaalsContact C-N 3.31Å; W242-E244 PolarHBondContact O-N 2.99Å; W242-Q277 HydrophobicContact CD2-CG 4.15Å; W242-Q277 HydrophobicContact CG-CG 4.28Å; W242-Q277 HydrophobicContact CZ2-CB 4.25Å; W242-Q277 HydrophobicContact CZ2-CG 4.24Å; W242-F281 AromaticContact CH2-CE2 3.76Å; W242-F281 HydrophobicContact CH2-CE2 3.76Å; W242-F281 HydrophobicContact CZ2-CE2 4.32Å; W242-W334 AromaticContact CE2-CH2 3.94Å; W242-W334 AromaticContact CZ2-CH2 3.98Å; W242-W334 HydrophobicContact CZ2-CH2 3.98Å; W242-W334 HydrophobicContact CZ2-CZ3 4.32Å; W242-W334 AromaticContact NE1-CH2 3.78Å; W242-W334 AromaticContact NE1-CZ3 3.81Å; W242-T362 HydrophobicContact CH2-CG2 3.93Å; W242-T362 HydrophobicContact CZ2-CG2 3.85Å; W242-H550 AromaticContact CD1-CD2 3.9Å; W242-H550 AromaticContact NE1-CD2 3.52Å
243S86.4Confident92.7Very high75 Ų7538.9 Ų38.952%0.52423%0.229SC..SBendtrans-80.2-4.3-17568.10000115.3N241 N245N241-S243 VanDerWaalsContact OD1-CB 3.32Å; N241-S243 WeakPolarHBondContact OD1-CB 3.49Å; N241-S243 PolarHBondContact OD1-N 2.83Å; N241-S243 PolarHBondContact OD1-OG 3.08Å; S243-N245 PolarHBondContact O-N 2.93Å; S243-N245 VanDerWaalsContact O-N 3.09Å; S243-N245 PolarHBondContact OG-N 2.91Å; S243-N245 PolarHBondContact OG-O 3.27Å
244E85.8Confident92.8Very high55 Ų5538.5 Ų38.526%0.25723%0.225SC..SBendtrans60.71.1-166.7-60.8-69.1121.900115.4W242 Y246 L549 T590W242-E244 VanDerWaalsContact C-N 3.31Å; W242-E244 PolarHBondContact O-N 2.99Å; E244-Y246 PolarHBondContact OE1-OH 3.45Å; E244-L549 HydrophobicContact CG-CD2 3.43Å; E244-L549 VanDerWaalsContact CG-CD2 3.43Å; E244-T590 WeakPolarHBondContact OE2-CB 3.48Å; E244-T590 PolarHBondContact OE2-N 2.92Å; E244-T590 VanDerWaalsContact OE2-N 3.08Å; E244-T590 PolarHBondContact OE2-OG1 3.38Å
245N89.8Confident93.4Very high86 Ų8639 Ų3946%0.4623%0.226SC..  trans-101.5110.7171.4-176.94.3000110.4N241 S243 T247N241-N245 PolarHBondContact ND2-O 2.61Å; S243-N245 PolarHBondContact O-N 2.93Å; S243-N245 VanDerWaalsContact O-N 3.09Å; S243-N245 PolarHBondContact OG-N 2.91Å; S243-N245 PolarHBondContact OG-O 3.27Å; N245-T247 WeakPolarHBondContact OD1-CG2 3.03Å; N245-T247 PolarHBondContact OD1-N 2.94Å; N245-T247 PolarHBondContact OD1-OG1 2.97Å
246Y92.9Very high93.7Very high21 Ų2135.6 Ų35.68%0.08221%0.208CC..  trans-121.825.5-178.3-47.4-67.6000112.3N241 E244 D248 G249 N251 P252 Y275 Q277N241-Y246 HydrophobicContact CB-CD1 4.42Å; N241-Y246 HydrophobicContact CB-CE1 4.1Å; N241-Y246 WeakPolarHBondContact O-CE1 3.12Å; E244-Y246 PolarHBondContact OE1-OH 3.45Å; Y246-D248 PolarHBondContact O-N 2.86Å; Y246-D248 VanDerWaalsContact O-N 3.14Å; Y246-G249 CarbonylContact O-C 3.59Å; Y246-G249 PolarHBondContact O-N 3.22Å; Y246-G249 VanDerWaalsContact O-N 3.07Å; Y246-N251 HydrophobicContact CD2-CB 3.74Å; Y246-N251 WeakPolarHBondContact CD2-ND2 3.16Å; Y246-N251 HydrophobicContact CE2-CB 4.33Å; Y246-N251 HydrophobicContact CG-CB 4.16Å; Y246-P252 HydrophobicContact CD1-CG 4.42Å; Y246-P252 HydrophobicContact CE1-CG 3.87Å; Y246-Y275 AromaticContact CD1-CD2 3.83Å; Y246-Y275 HydrophobicContact CD1-CD2 3.83Å; Y246-Y275 HydrophobicContact CD1-CG 4.32Å; Y246-Q277 PolarHBondContact OH-NE2 3.04Å
247T92.6Very high93.7Very high129 Ų12935.6 Ų35.679%0.79121%0.208SC*.THydrogen-bonded Turntrans-60.9-24.2-171.844.50000114.7N245N245-T247 WeakPolarHBondContact OD1-CG2 3.03Å; N245-T247 PolarHBondContact OD1-N 2.94Å; N245-T247 PolarHBondContact OD1-OG1 2.97Å
248D95Very high93.7Very high87 Ų8735.6 Ų35.647%0.46521%0.208SC..THydrogen-bonded Turntrans-106.113.2178.369-41.2000113.6Y246 R274 Y275Y246-D248 PolarHBondContact O-N 2.86Å; Y246-D248 VanDerWaalsContact O-N 3.14Å; D248-R274 IonicContact OD2-CZ 2.78Å; D248-R274 IonicContact OD2-NH1 2.79Å; D248-R274 PolarHBondContact OD2-NH1 3.09Å; D248-Y275 VanDerWaalsContact CG-OH 3.23Å; D248-Y275 WeakPolarHBondContact OD1-CE2 3.49Å; D248-Y275 PolarHBondContact OD1-OH 2.88Å; D248-Y275 PolarHBondContact OD2-OH 3.36Å
249G95.2Very high93.7Very high34 Ų3436.3 Ų36.335%0.35121%0.212SC..SBendtrans-154.3-170.2-18000000113.5Y246Y246-G249 CarbonylContact O-C 3.59Å; Y246-G249 PolarHBondContact O-N 3.22Å; Y246-G249 VanDerWaalsContact O-N 3.07Å
250A94.2Very high93.7Very high25 Ų2535.1 Ų35.121%0.20721%0.209CC..  trans-83.9137.8169.700000110.1P252 W255 R274 Y275A250-P252 WeakPolarHBondContact O-CD 3.48Å; A250-W255 HydrophobicContact CB-CH2 4.18Å; A250-W255 HydrophobicContact CB-CZ2 3.49Å; A250-W255 VanDerWaalsContact CB-CZ2 3.49Å; A250-R274 PolarHBondContact N-O 2.89Å; A250-Y275 PolarHBondContact O-N 3.36Å; A250-Y275 VanDerWaalsContact O-N 3.14Å
251N93.9Very high93.8Very high12 Ų1234 Ų346%0.06420%0.198CC..  trans-63.3126.9166.4-179.8-38.3000108.7Y246 A253 E254Y246-N251 HydrophobicContact CD2-CB 3.74Å; Y246-N251 WeakPolarHBondContact CD2-ND2 3.16Å; Y246-N251 HydrophobicContact CE2-CB 4.33Å; Y246-N251 HydrophobicContact CG-CB 4.16Å; N251-A253 PolarHBondContact O-N 3.37Å; N251-A253 VanDerWaalsContact O-N 3.07Å; N251-A253 WeakPolarHBondContact OD1-CB 3.11Å; N251-A253 PolarHBondContact OD1-N 2.89Å; N251-E254 HydrophobicContact CB-CG 4.06Å; N251-E254 WeakPolarHBondContact O-CB 3.49Å; N251-E254 PolarHBondContact O-N 2.75Å
252P94.8Very high94.1Very high0 Ų033.1 Ų33.10%019%0.193CC..G310 helixtrans-52-31.3-179.4-29.335.9000115Y246 A250 E254 Q277 W279 V280Y246-P252 HydrophobicContact CD1-CG 4.42Å; Y246-P252 HydrophobicContact CE1-CG 3.87Å; A250-P252 WeakPolarHBondContact O-CD 3.48Å; P252-E254 VanDerWaalsContact C-N 3.31Å; P252-E254 PolarHBondContact O-N 3.39Å; P252-Q277 HydrophobicContact CB-CB 4.11Å; P252-Q277 HydrophobicContact CB-CG 3.88Å; P252-Q277 HydrophobicContact CG-CG 3.83Å; P252-W279 HydrophobicContact CB-CZ2 4Å; P252-V280 HydrophobicContact CB-CG2 4.21Å
253A92.3Very high94.5Very high6 Ų633.3 Ų33.35%0.0520%0.196CC..G310 helixtrans-74.5-18.1179.300000113.4N251 W279 T590 D707 K709N251-A253 PolarHBondContact O-N 3.37Å; N251-A253 VanDerWaalsContact O-N 3.07Å; N251-A253 WeakPolarHBondContact OD1-CB 3.11Å; N251-A253 PolarHBondContact OD1-N 2.89Å; A253-W279 HydrophobicContact CB-CZ2 4.38Å; A253-T590 HydrophobicContact CB-CG2 3.44Å; A253-T590 VanDerWaalsContact CB-CG2 3.44Å; A253-D707 HydrophobicContact CB-CB 3.9Å; A253-D707 WeakPolarHBondContact O-CB 3.35Å; A253-K709 WeakPolarHBondContact O-CE 3.3Å; A253-K709 PolarHBondContact O-NZ 2.9Å
254E93.8Very high95.1Very high47 Ų4733.7 Ų33.722%0.2219%0.189CC..G310 helixtrans-75.4-25.1179.2-70.5-177.2-158.600112.7N251 P252 T256 R701 K709N251-E254 HydrophobicContact CB-CG 4.06Å; N251-E254 WeakPolarHBondContact O-CB 3.49Å; N251-E254 PolarHBondContact O-N 2.75Å; P252-E254 VanDerWaalsContact C-N 3.31Å; P252-E254 PolarHBondContact O-N 3.39Å; E254-T256 PolarHBondContact O-N 2.76Å; E254-R701 HydrophobicContact CG-CB 4.33Å; E254-R701 WeakPolarHBondContact OE1-CD 3.41Å; E254-R701 IonicContact OE1-NH1 3.76Å; E254-R701 WeakPolarHBondContact OE2-CD 3.48Å; E254-R701 IonicContact OE2-NE 3.23Å; E254-K709 PolarHBondContact O-NZ 3.01Å; E254-K709 VanDerWaalsContact O-NZ 3.11Å
255W95.9Very high95.7Very high22 Ų2231.1 Ų31.18%0.08318%0.177CC..  trans-59134.5179-64.9119.2000112.1W181 A250 A260 I261 V273 Y275 V280 K709W181-W255 HydrophobicContact CH2-CB 3.51Å; W181-W255 HydrophobicContact CH2-CG 4.5Å; W181-W255 HydrophobicContact CZ2-CB 4.45Å; W181-W255 HydrophobicContact CZ3-CB 3.95Å; W181-W255 WeakPolarHBondContact CZ3-O 3.1Å; A250-W255 HydrophobicContact CB-CH2 4.18Å; A250-W255 HydrophobicContact CB-CZ2 3.49Å; A250-W255 VanDerWaalsContact CB-CZ2 3.49Å; W255-A260 HydrophobicContact CZ3-CB 4.18Å; W255-I261 HydrophobicContact CB-CD1 4.44Å; W255-I261 HydrophobicContact CD2-CD1 3.8Å; W255-I261 HydrophobicContact CD2-CG1 3.74Å; W255-I261 HydrophobicContact CE3-CD1 4.08Å; W255-I261 HydrophobicContact CE3-CG1 3.62Å; W255-I261 HydrophobicContact CG-CD1 3.95Å; W255-I261 HydrophobicContact CG-CG1 4.43Å; W255-I261 HydrophobicContact CH2-CG1 3.94Å; W255-I261 HydrophobicContact CZ2-CG1 4.04Å; W255-I261 HydrophobicContact CZ3-CG1 3.73Å; W255-V273 HydrophobicContact CH2-CG1 4.07Å; W255-V273 HydrophobicContact CZ2-CG1 3.76Å; W255-Y275 PolarHBondContact NE1-O 3.4Å; W255-V280 HydrophobicContact CG-CG1 4.47Å; W255-K709 PolarHBondContact O-NZ 3.14Å
256T95.1Very high96.1Very high3 Ų332.1 Ų32.12%0.01818%0.175CC..  trans-114.6-10.9178.236.40000112.5N182 E254 E658 Q697 N699 K709N182-T256 PolarHBondContact N-O 2.94Å; E254-T256 PolarHBondContact O-N 2.76Å; T256-E658 WeakPolarHBondContact CB-OE1 3.43Å; T256-E658 PolarHBondContact OG1-OE1 2.81Å; T256-Q697 PolarHBondContact O-OE1 3.07Å; T256-N699 HydrophobicContact CG2-CB 3.43Å; T256-N699 VanDerWaalsContact CG2-CB 3.43Å; T256-K709 HydrophobicContact CG2-CD 4.19Å
257G97.3Very high96.3Very high0 Ų035.1 Ų35.10%021%0.205CC..BIsolated β-bridgetrans-169.5162.7-177.700000113.8N182N182-G257 CarbonylContact O-C 3.56Å; N182-G257 WeakPolarHBondContact O-CA 3.45Å
258S98.8Very high96.6Very high0 Ų032.3 Ų32.30%019%0.187CC..Hα-helixtrans-79.4-26.6-178.7-53.90000112.9W181 N182 A260 I261 L262 A283 T287W181-S258 PolarHBondContact NE1-OG 3.33Å; N182-S258 PolarHBondContact O-N 3.05Å; S258-A260 PolarHBondContact O-N 3.12Å; S258-I261 PolarHBondContact O-N 3.04Å; S258-L262 PolarHBondContact O-N 3.05Å; S258-A283 PolarHBondContact OG-O 3.16Å; S258-A283 VanDerWaalsContact OG-O 3.12Å; S258-T287 WeakPolarHBondContact CB-OG1 3.37Å; S258-T287 PolarHBondContact OG-OG1 3.49Å
259V98.3Very high96.7Very high14 Ų1430.5 Ų30.59%0.08519%0.189CC..Hα-helixtrans-57.9-47-174.1177.90000111.6E187 I190 I261 K263E187-V259 HydrophobicContact CB-CG1 4.08Å; E187-V259 HydrophobicContact CB-CG2 4.13Å; E187-V259 HydrophobicContact CG-CG1 4.38Å; E187-V259 HydrophobicContact CG-CG2 3.97Å; I190-V259 HydrophobicContact CD1-CB 4.48Å; I190-V259 HydrophobicContact CD1-CG1 4.19Å; V259-I261 PolarHBondContact O-N 3.46Å; V259-K263 HydrophobicContact CG1-CD 3.98Å; V259-K263 WeakPolarHBondContact O-CB 3.49Å; V259-K263 WeakPolarHBondContact O-CG 3.22Å; V259-K263 PolarHBondContact O-N 3.33Å
260A97.1Very high96.8Very high23 Ų2329.4 Ų29.419%0.1918%0.176CC..Hα-helixtrans-64.5-40.2179.700000112W255 S258 Q264W255-A260 HydrophobicContact CZ3-CB 4.18Å; S258-A260 PolarHBondContact O-N 3.12Å; A260-Q264 WeakPolarHBondContact O-CB 3.15Å; A260-Q264 PolarHBondContact O-N 2.83Å
261I98.7Very high96.9Very high0 Ų033 Ų330%019%0.189CC..Hα-helixtrans-63.7-53178.8-62168.7000110.2W181 V237 L238 W255 S258 V259 K263 Q264 W265 V273 V280 V284W181-I261 HydrophobicContact CZ2-CD1 4.31Å; V237-I261 HydrophobicContact CG1-CG2 3.87Å; L238-I261 HydrophobicContact CD1-CG2 4.46Å; L238-I261 HydrophobicContact CD2-CD1 4.49Å; L238-I261 HydrophobicContact CD2-CG2 3.72Å; L238-I261 HydrophobicContact CG-CG2 4.03Å; W255-I261 HydrophobicContact CB-CD1 4.44Å; W255-I261 HydrophobicContact CD2-CD1 3.8Å; W255-I261 HydrophobicContact CD2-CG1 3.74Å; W255-I261 HydrophobicContact CE3-CD1 4.08Å; W255-I261 HydrophobicContact CE3-CG1 3.62Å; W255-I261 HydrophobicContact CG-CD1 3.95Å; W255-I261 HydrophobicContact CG-CG1 4.43Å; W255-I261 HydrophobicContact CH2-CG1 3.94Å; W255-I261 HydrophobicContact CZ2-CG1 4.04Å; W255-I261 HydrophobicContact CZ3-CG1 3.73Å; S258-I261 PolarHBondContact O-N 3.04Å; V259-I261 PolarHBondContact O-N 3.46Å; I261-K263 PolarHBondContact O-N 2.95Å; I261-Q264 PolarHBondContact O-N 3.14Å; I261-W265 PolarHBondContact O-N 3.37Å; I261-V273 HydrophobicContact CG2-CB 4.22Å; I261-V273 HydrophobicContact CG2-CG1 4.21Å; I261-V273 HydrophobicContact CG2-CG2 4.32Å; I261-V280 HydrophobicContact CD1-CG1 3.5Å; I261-V284 HydrophobicContact CB-CG2 4.29Å; I261-V284 HydrophobicContact CD1-CG2 3.79Å; I261-V284 HydrophobicContact CG2-CG2 4.11Å
262L98.8Very high97.1Very high0 Ų033.8 Ų33.80%019%0.194CC..Hα-helixtrans-62.8-42.5-178.4-73.9171000111.9I190 I193 V237 S258 W265 Y266 V284 T287 V288I190-L262 HydrophobicContact CD1-CB 4.05Å; I190-L262 HydrophobicContact CD1-CD1 4.2Å; I190-L262 HydrophobicContact CG2-CD1 4.36Å; I193-L262 HydrophobicContact CG2-CB 4.1Å; I193-L262 HydrophobicContact CG2-CD2 4.2Å; V237-L262 HydrophobicContact CG1-CD2 4.22Å; V237-L262 HydrophobicContact CG2-CD2 4.4Å; S258-L262 PolarHBondContact O-N 3.05Å; L262-W265 PolarHBondContact O-N 3.44Å; L262-Y266 WeakPolarHBondContact O-CB 3.27Å; L262-Y266 PolarHBondContact O-N 3.43Å; L262-V284 HydrophobicContact CD2-CG1 3.88Å; L262-V284 HydrophobicContact CG-CG1 4.15Å; L262-T287 HydrophobicContact CD1-CG2 3.91Å; L262-V288 HydrophobicContact CD1-CG2 4.37Å; L262-V288 HydrophobicContact CD2-CG2 4.24Å
263K98.3Very high97.3Very high60 Ų6033.9 Ų33.926%0.26120%0.195SC..Hα-helixtrans-65.6-38.5175.8-74.1-177.4177.1-179.40112E188 I190 I193 V259 I261 A267E188-K263 WeakPolarHBondContact O-CE 3.29Å; E188-K263 PolarHBondContact O-NZ 2.82Å; E188-K263 VanDerWaalsContact O-NZ 3.09Å; I190-K263 HydrophobicContact CD1-CG 4.36Å; I193-K263 HydrophobicContact CD1-CG 3.96Å; V259-K263 HydrophobicContact CG1-CD 3.98Å; V259-K263 WeakPolarHBondContact O-CB 3.49Å; V259-K263 WeakPolarHBondContact O-CG 3.22Å; V259-K263 PolarHBondContact O-N 3.33Å; I261-K263 PolarHBondContact O-N 2.95Å; K263-A267 WeakPolarHBondContact O-CB 3.47Å; K263-A267 PolarHBondContact O-N 2.98Å
264Q98Very high97.6Very high83 Ų8339.3 Ų39.339%0.38821%0.214SC..Hα-helixtrans-64-50.4175.6-178.8178.1-19.800111A260 I261 Y266 A267 T268 V273A260-Q264 WeakPolarHBondContact O-CB 3.15Å; A260-Q264 PolarHBondContact O-N 2.83Å; I261-Q264 PolarHBondContact O-N 3.14Å; Q264-Y266 VanDerWaalsContact C-N 3.28Å; Q264-Y266 PolarHBondContact O-N 2.74Å; Q264-A267 PolarHBondContact O-N 3.33Å; Q264-T268 HydrophobicContact CG-CG2 4.4Å; Q264-T268 WeakPolarHBondContact O-CG2 3.49Å; Q264-T268 PolarHBondContact O-N 3.42Å; Q264-T268 PolarHBondContact O-OG1 2.96Å; Q264-V273 HydrophobicContact CB-CG2 4.09Å; Q264-V273 HydrophobicContact CG-CG2 3.99Å
265W98.7Very high97.8Very high1 Ų138 Ų380%0.00421%0.207CC..Hα-helixtrans-53.9-46.4176.9176.177.8000111.5I193 L197 K200 M228 G236 V237 I261 L262 T268 C270 Q271 V273I193-W265 HydrophobicContact CG2-CE3 3.96Å; I193-W265 HydrophobicContact CG2-CZ3 4.01Å; L197-W265 HydrophobicContact CB-CH2 4.09Å; L197-W265 HydrophobicContact CB-CZ3 4.23Å; K200-W265 HydrophobicContact CB-CH2 4.37Å; K200-W265 HydrophobicContact CB-CZ2 4.38Å; K200-W265 HydrophobicContact CG-CH2 4.12Å; K200-W265 HydrophobicContact CG-CZ2 4.3Å; M228-W265 HydrophobicContact CE-CZ2 4.14Å; G236-W265 PolarHBondContact O-NE1 2.88Å; V237-W265 HydrophobicContact CB-CG 4.46Å; V237-W265 HydrophobicContact CG1-CB 4.11Å; V237-W265 HydrophobicContact CG1-CG 4.15Å; V237-W265 HydrophobicContact CG2-CD2 4.2Å; V237-W265 HydrophobicContact CG2-CG 4.4Å; I261-W265 PolarHBondContact O-N 3.37Å; L262-W265 PolarHBondContact O-N 3.44Å; W265-T268 PolarHBondContact O-OG1 2.96Å; W265-T268 VanDerWaalsContact O-OG1 3.12Å; W265-C270 HydrophobicContact CD2-CB 4.27Å; W265-C270 HydrophobicContact CH2-CB 3.99Å; W265-C270 WeakPolarHBondContact CH2-SG 3.27Å; W265-C270 HydrophobicContact CZ2-CB 3.42Å; W265-C270 VanDerWaalsContact CZ2-CB 3.42Å; W265-C270 PolarHBondContact NE1-O 3.48Å; W265-C270 WeakPolarHBondContact O-CA 3.33Å; W265-C270 PolarHBondContact O-N 2.68Å; W265-Q271 VanDerWaalsContact CD1-O 3.24Å; W265-V273 HydrophobicContact CB-CG2 3.78Å
266Y98.3Very high97.8Very high107 Ų10736.9 Ų36.942%0.4220%0.203SC..Hα-helixtrans-66.3-45.3178.7-174.3-100000112.6I193 K196 L262 Q264 T268 G269I193-Y266 HydrophobicContact CD1-CG 4.26Å; I193-Y266 HydrophobicContact CG1-CD1 4.24Å; I193-Y266 HydrophobicContact CG1-CD2 3.86Å; I193-Y266 HydrophobicContact CG1-CG 3.7Å; K196-Y266 HydrophobicContact CB-CD2 4.47Å; K196-Y266 HydrophobicContact CB-CE2 4.2Å; K196-Y266 HydrophobicContact CG-CD2 4.25Å; K196-Y266 HydrophobicContact CG-CE2 3.98Å; L262-Y266 WeakPolarHBondContact O-CB 3.27Å; L262-Y266 PolarHBondContact O-N 3.43Å; Q264-Y266 VanDerWaalsContact C-N 3.28Å; Q264-Y266 PolarHBondContact O-N 2.74Å; Y266-T268 VanDerWaalsContact C-N 3.29Å; Y266-T268 PolarHBondContact O-N 3.42Å; Y266-G269 PolarHBondContact O-N 3.5Å; Y266-G269 VanDerWaalsContact O-N 3.13Å
267A97.9Very high97.8Very high85 Ų8536.9 Ų36.970%0.70220%0.203SC*.Hα-helixtrans-66.5-27.9-177.900000113.4K263 Q264 G269K263-A267 WeakPolarHBondContact O-CB 3.47Å; K263-A267 PolarHBondContact O-N 2.98Å; Q264-A267 PolarHBondContact O-N 3.33Å; A267-G269 PolarHBondContact O-N 2.88Å
268T97.4Very high97.8Very high70 Ų7036.9 Ų36.943%0.42920%0.203SC..THydrogen-bonded Turntrans-85.910.8176.257.90000113.2Q264 W265 Y266 Q271Q264-T268 HydrophobicContact CG-CG2 4.4Å; Q264-T268 WeakPolarHBondContact O-CG2 3.49Å; Q264-T268 PolarHBondContact O-N 3.42Å; Q264-T268 PolarHBondContact O-OG1 2.96Å; W265-T268 PolarHBondContact O-OG1 2.96Å; W265-T268 VanDerWaalsContact O-OG1 3.12Å; Y266-T268 VanDerWaalsContact C-N 3.29Å; Y266-T268 PolarHBondContact O-N 3.42Å; T268-Q271 VanDerWaalsContact O-CG 3.24Å; T268-Q271 WeakPolarHBondContact O-CG 3.44Å; T268-Q271 PolarHBondContact OG1-O 2.98Å
269G97.3Very high97.8Very high49 Ų4937.1 Ų37.151%0.50520%0.204SC..THydrogen-bonded Turntrans76.937.8-179.400000113.1Y266 A267Y266-G269 PolarHBondContact O-N 3.5Å; Y266-G269 VanDerWaalsContact O-N 3.13Å; A267-G269 PolarHBondContact O-N 2.88Å
270C97.8Very high97.8Very high11 Ų1136.4 Ų36.47%0.07420%0.2CC..SBendtrans64.436.9-177.5-560000113.2K200 W265K200-C270 HydrophobicContact CG-CB 4.47Å; W265-C270 HydrophobicContact CD2-CB 4.27Å; W265-C270 HydrophobicContact CH2-CB 3.99Å; W265-C270 WeakPolarHBondContact CH2-SG 3.27Å; W265-C270 HydrophobicContact CZ2-CB 3.42Å; W265-C270 VanDerWaalsContact CZ2-CB 3.42Å; W265-C270 PolarHBondContact NE1-O 3.48Å; W265-C270 WeakPolarHBondContact O-CA 3.33Å; W265-C270 PolarHBondContact O-N 2.68Å
271Q97.6Very high97.9Very high101 Ų10135.3 Ų35.347%0.47219%0.19SC..PPolyproline II helixtrans-89.1139.8174-65.5-61.1-48.900110.6W265 T268 V273W265-Q271 VanDerWaalsContact CD1-O 3.24Å; T268-Q271 VanDerWaalsContact O-CG 3.24Å; T268-Q271 WeakPolarHBondContact O-CG 3.44Å; T268-Q271 PolarHBondContact OG1-O 2.98Å; Q271-V273 PolarHBondContact O-N 3.1Å
272P98.2Very high97.9Very high28 Ų2835.4 Ų35.418%0.18219%0.191CC..PPolyproline II helixtrans-54.1132.5-178.1-28.935.3000113.4N235 N239N235-P272 WeakPolarHBondContact OD1-CD 3.11Å; N235-P272 WeakPolarHBondContact OD1-CG 3.44Å; N239-P272 HydrophobicContact CB-CB 4.23Å
273V98.6Very high97.9Very high1 Ų135.4 Ų35.41%0.00619%0.191CC..EExtended strand (participates in β ladder)trans-82.3126176178.20000109.2V237 L238 N239 W255 I261 Q264 W265 Q271V237-V273 PolarHBondContact O-N 2.72Å; L238-V273 HydrophobicContact CD2-CB 4.17Å; L238-V273 HydrophobicContact CD2-CG1 4.32Å; N239-V273 PolarHBondContact N-O 2.92Å; W255-V273 HydrophobicContact CH2-CG1 4.07Å; W255-V273 HydrophobicContact CZ2-CG1 3.76Å; I261-V273 HydrophobicContact CG2-CB 4.22Å; I261-V273 HydrophobicContact CG2-CG1 4.21Å; I261-V273 HydrophobicContact CG2-CG2 4.32Å; Q264-V273 HydrophobicContact CB-CG2 4.09Å; Q264-V273 HydrophobicContact CG-CG2 3.99Å; W265-V273 HydrophobicContact CB-CG2 3.78Å; Q271-V273 PolarHBondContact O-N 3.1Å
274R97.9Very high97.9Very high120 Ų12032.5 Ų32.545%0.45318%0.178SC..EExtended strand (participates in β ladder)trans-97.2124.6177-66.4-179.5-174.4-173.44.2109.7N239 D248 A250N239-R274 HydrophobicContact CB-CG 4.13Å; D248-R274 IonicContact OD2-CZ 2.78Å; D248-R274 IonicContact OD2-NH1 2.79Å; D248-R274 PolarHBondContact OD2-NH1 3.09Å; A250-R274 PolarHBondContact N-O 2.89Å
275Y97.3Very high97.9Very high19 Ų1928.6 Ų28.68%0.07516%0.16CC..EExtended strand (participates in β ladder)cis-129164.3-5.5-67.6-76.3000111.7N239 N241 Y246 D248 A250 W255N239-Y275 HydrophobicContact CB-CD1 4.24Å; N239-Y275 HydrophobicContact CB-CE1 4.49Å; N239-Y275 CarbonylContact O-C 3.55Å; N239-Y275 WeakPolarHBondContact O-CA 3.07Å; N239-Y275 WeakPolarHBondContact O-CD1 3.23Å; N239-Y275 WeakPolarHBondContact OD1-CD1 3.35Å; N239-Y275 WeakPolarHBondContact OD1-CE1 3.33Å; N241-Y275 HydrophobicContact CB-CD1 3.36Å; N241-Y275 HydrophobicContact CB-CD2 4.31Å; N241-Y275 HydrophobicContact CB-CE1 3.82Å; N241-Y275 HydrophobicContact CB-CG 3.63Å; Y246-Y275 AromaticContact CD1-CD2 3.83Å; Y246-Y275 HydrophobicContact CD1-CD2 3.83Å; Y246-Y275 HydrophobicContact CD1-CG 4.32Å; D248-Y275 VanDerWaalsContact CG-OH 3.23Å; D248-Y275 WeakPolarHBondContact OD1-CE2 3.49Å; D248-Y275 PolarHBondContact OD1-OH 2.88Å; D248-Y275 PolarHBondContact OD2-OH 3.36Å; A250-Y275 PolarHBondContact O-N 3.36Å; A250-Y275 VanDerWaalsContact O-N 3.14Å; W255-Y275 PolarHBondContact NE1-O 3.4Å
276G96.8Very high98Very high0 Ų028.5 Ų28.50%016%0.16CC..EExtended strand (participates in β ladder)trans-124.1158.8172.400000113N239 G240 N241N239-G276 PolarHBondContact O-N 3.39Å; G240-G276 WeakPolarHBondContact CA-O 3.41Å; N241-G276 PolarHBondContact N-O 2.98Å
277Q95.4Very high98Very high3 Ų323.4 Ų23.41%0.01414%0.14CC..  trans-130.8176.9165.1-74.4-177.5-0.600108.5N241 W242 Y246 P252 W279 V280 F281N241-Q277 PolarHBondContact O-NE2 3.29Å; W242-Q277 HydrophobicContact CD2-CG 4.15Å; W242-Q277 HydrophobicContact CG-CG 4.28Å; W242-Q277 HydrophobicContact CZ2-CB 4.25Å; W242-Q277 HydrophobicContact CZ2-CG 4.24Å; Y246-Q277 PolarHBondContact OH-NE2 3.04Å; P252-Q277 HydrophobicContact CB-CB 4.11Å; P252-Q277 HydrophobicContact CB-CG 3.88Å; P252-Q277 HydrophobicContact CG-CG 3.83Å; Q277-W279 VanDerWaalsContact C-N 3.28Å; Q277-W279 HydrophobicContact CB-CD2 4.41Å; Q277-W279 HydrophobicContact CB-CE3 3.92Å; Q277-W279 HydrophobicContact CB-CH2 3.81Å; Q277-W279 HydrophobicContact CB-CZ2 4.26Å; Q277-W279 HydrophobicContact CB-CZ3 3.59Å; Q277-W279 HydrophobicContact CG-CH2 4.35Å; Q277-W279 HydrophobicContact CG-CZ3 4.42Å; Q277-W279 PolarHBondContact O-N 3.1Å; Q277-V280 WeakPolarHBondContact O-CA 3.43Å; Q277-V280 WeakPolarHBondContact O-CB 3.46Å; Q277-V280 PolarHBondContact O-N 2.99Å; Q277-F281 WeakPolarHBondContact O-CD2 3.44Å; Q277-F281 PolarHBondContact O-N 3.35Å
278C96.8Very high98Very high0 Ų019.4 Ų19.40%011%0.106CC..Hα-helixtrans-47-45.7-16763.20000113.9V280 F281 A282 W334 H337 V338 T362 H550C278-V280 VanDerWaalsContact C-N 3.32Å; C278-V280 PolarHBondContact O-N 3.25Å; C278-F281 PolarHBondContact O-N 2.81Å; C278-A282 WeakPolarHBondContact O-CB 3.48Å; C278-A282 PolarHBondContact O-N 2.83Å; C278-W334 HydrophobicContact CB-CZ3 4.27Å; C278-H337 VanDerWaalsContact CB-ND1 3.27Å; C278-H337 WeakPolarHBondContact CB-ND1 3.44Å; C278-V338 HydrophobicContact CB-CB 4.43Å; C278-T362 WeakPolarHBondContact CA-OG1 3.41Å; C278-T362 HydrophobicContact CB-CG2 4.11Å; C278-T362 WeakPolarHBondContact CB-OG1 3.27Å; C278-H550 PolarHBondContact SG-NE2 3.22Å
279W97.9Very high98.1Very high4 Ų416 Ų162%0.0159%0.086CC..Hα-helixtrans-66-32.8178.968.689.1000113.6I168 W181 P252 A253 Q277 A283 F336 V338 H550I168-W279 HydrophobicContact CD1-CB 4.2Å; I168-W279 HydrophobicContact CG2-CB 3.92Å; W181-W279 AromaticContact CZ3-CD1 3.95Å; P252-W279 HydrophobicContact CB-CZ2 4Å; A253-W279 HydrophobicContact CB-CZ2 4.38Å; Q277-W279 VanDerWaalsContact C-N 3.28Å; Q277-W279 HydrophobicContact CB-CD2 4.41Å; Q277-W279 HydrophobicContact CB-CE3 3.92Å; Q277-W279 HydrophobicContact CB-CH2 3.81Å; Q277-W279 HydrophobicContact CB-CZ2 4.26Å; Q277-W279 HydrophobicContact CB-CZ3 3.59Å; Q277-W279 HydrophobicContact CG-CH2 4.35Å; Q277-W279 HydrophobicContact CG-CZ3 4.42Å; Q277-W279 PolarHBondContact O-N 3.1Å; W279-A283 WeakPolarHBondContact O-CB 3.29Å; W279-A283 PolarHBondContact O-N 3.26Å; W279-F336 HydrophobicContact CE3-CE2 4.05Å; W279-F336 HydrophobicContact CE3-CZ 4.15Å; W279-F336 HydrophobicContact CZ3-CZ 4.26Å; W279-V338 HydrophobicContact CB-CB 4.15Å; W279-V338 HydrophobicContact CB-CG1 4.32Å; W279-V338 HydrophobicContact CB-CG2 3.91Å; W279-H550 AromaticContact CE3-CE1 4Å; W279-H550 AromaticContact CZ3-CE1 3.74Å; W279-H550 AromaticContact CZ3-ND1 3.62Å
280V98.6Very high98.2Very high0 Ų014 Ų140%06%0.063CC..Hα-helixtrans-70.4-44.8176.9-170.40000109.4W181 L238 P252 W255 I261 Q277 C278 A283 V284W181-V280 HydrophobicContact CH2-CB 4.39Å; W181-V280 HydrophobicContact CH2-CG1 4.11Å; W181-V280 HydrophobicContact CH2-CG2 4.21Å; W181-V280 HydrophobicContact CZ2-CG1 4.48Å; L238-V280 HydrophobicContact CD1-CB 4.41Å; L238-V280 HydrophobicContact CD1-CG1 3.73Å; L238-V280 HydrophobicContact CD2-CG1 4.14Å; P252-V280 HydrophobicContact CB-CG2 4.21Å; W255-V280 HydrophobicContact CG-CG1 4.47Å; I261-V280 HydrophobicContact CD1-CG1 3.5Å; Q277-V280 WeakPolarHBondContact O-CA 3.43Å; Q277-V280 WeakPolarHBondContact O-CB 3.46Å; Q277-V280 PolarHBondContact O-N 2.99Å; C278-V280 VanDerWaalsContact C-N 3.32Å; C278-V280 PolarHBondContact O-N 3.25Å; V280-A283 PolarHBondContact O-N 2.66Å; V280-V284 WeakPolarHBondContact O-CB 3.24Å; V280-V284 WeakPolarHBondContact O-CG2 3.21Å; V280-V284 PolarHBondContact O-N 3.44Å
281F98.8Very high98.2Very high0 Ų013.5 Ų13.50%06%0.06CC..Hα-helixtrans-57.9-52.6173.9-66.2-76000110.4I229 N230 L238 W242 Q277 C278 A283 V284 M285 A361 T362I229-F281 HydrophobicContact CG2-CB 4.2Å; I229-F281 HydrophobicContact CG2-CD1 3.95Å; I229-F281 WeakPolarHBondContact CG2-O 3.42Å; N230-F281 HydrophobicContact CB-CD1 4.07Å; N230-F281 HydrophobicContact CB-CE1 3.69Å; L238-F281 HydrophobicContact CB-CD1 3.91Å; L238-F281 HydrophobicContact CB-CE1 3.41Å; L238-F281 VanDerWaalsContact CB-CE1 3.41Å; L238-F281 HydrophobicContact CB-CZ 4.13Å; L238-F281 HydrophobicContact CD1-CD1 3.97Å; L238-F281 HydrophobicContact CD1-CE1 4.28Å; L238-F281 HydrophobicContact CD1-CG 4.46Å; W242-F281 AromaticContact CH2-CE2 3.76Å; W242-F281 HydrophobicContact CH2-CE2 3.76Å; W242-F281 HydrophobicContact CZ2-CE2 4.32Å; Q277-F281 WeakPolarHBondContact O-CD2 3.44Å; Q277-F281 PolarHBondContact O-N 3.35Å; C278-F281 PolarHBondContact O-N 2.81Å; F281-A283 VanDerWaalsContact C-N 3.32Å; F281-A283 PolarHBondContact O-N 3Å; F281-V284 PolarHBondContact O-N 2.82Å; F281-M285 WeakPolarHBondContact O-CB 3.48Å; F281-M285 PolarHBondContact O-N 2.9Å; F281-A361 HydrophobicContact CB-CB 4.1Å; F281-T362 HydrophobicContact CD2-CG2 4.4Å
282A98.9Very high98.3Very high1 Ų18.7 Ų8.71%0.0084%0.037CC..Hα-helixtrans-62.1-37.7-177.900000112.9C278 C286 V298 V338 N340C278-A282 WeakPolarHBondContact O-CB 3.48Å; C278-A282 PolarHBondContact O-N 2.83Å; A282-C286 VanDerWaalsContact O-CB 3.3Å; A282-C286 WeakPolarHBondContact O-CB 2.93Å; A282-C286 PolarHBondContact O-N 2.71Å; A282-V298 HydrophobicContact CB-CG1 4.18Å; A282-V338 HydrophobicContact CB-CB 4.34Å; A282-V338 HydrophobicContact CB-CG1 3.69Å; A282-N340 WeakPolarHBondContact CA-OD1 3.46Å; A282-N340 PolarHBondContact O-ND2 2.87Å; A282-N340 PolarHBondContact O-OD1 3.48Å
283A98.9Very high98.3Very high0 Ų07.3 Ų7.30%03%0.028CC..Hα-helixtrans-74.3-38.3-178.900000113.1I168 W181 Y183 S258 W279 V280 F281 C286 T287I168-A283 HydrophobicContact CD1-CB 3.66Å; W181-A283 HydrophobicContact CD2-CB 3.77Å; W181-A283 HydrophobicContact CG-CB 3.96Å; W181-A283 HydrophobicContact CZ2-CB 3.75Å; W181-A283 VanDerWaalsContact NE1-CB 3.26Å; Y183-A283 HydrophobicContact CE1-CB 4.12Å; S258-A283 PolarHBondContact OG-O 3.16Å; S258-A283 VanDerWaalsContact OG-O 3.12Å; W279-A283 WeakPolarHBondContact O-CB 3.29Å; W279-A283 PolarHBondContact O-N 3.26Å; V280-A283 PolarHBondContact O-N 2.66Å; F281-A283 VanDerWaalsContact C-N 3.32Å; F281-A283 PolarHBondContact O-N 3Å; A283-C286 PolarHBondContact O-N 2.78Å; A283-T287 PolarHBondContact O-N 2.85Å; A283-T287 PolarHBondContact O-OG1 2.79Å
284V98.9Very high98.3Very high0 Ų07.3 Ų7.30%03%0.028CC..Hα-helixtrans-65.5-44.1172.2173.60000110.2I229 V237 L238 I261 L262 V280 F281 C286 T287 V288I229-V284 HydrophobicContact CD1-CG1 4.2Å; I229-V284 HydrophobicContact CG2-CB 4.3Å; I229-V284 HydrophobicContact CG2-CG1 4.26Å; V237-V284 HydrophobicContact CG1-CG1 4.27Å; L238-V284 HydrophobicContact CD1-CB 4.32Å; L238-V284 HydrophobicContact CD1-CG2 4.01Å; I261-V284 HydrophobicContact CB-CG2 4.29Å; I261-V284 HydrophobicContact CD1-CG2 3.79Å; I261-V284 HydrophobicContact CG2-CG2 4.11Å; L262-V284 HydrophobicContact CD2-CG1 3.88Å; L262-V284 HydrophobicContact CG-CG1 4.15Å; V280-V284 WeakPolarHBondContact O-CB 3.24Å; V280-V284 WeakPolarHBondContact O-CG2 3.21Å; V280-V284 PolarHBondContact O-N 3.44Å; F281-V284 PolarHBondContact O-N 2.82Å; V284-C286 PolarHBondContact O-N 3.38Å; V284-T287 WeakPolarHBondContact O-CB 3.43Å; V284-T287 PolarHBondContact O-N 2.91Å; V284-T287 VanDerWaalsContact O-N 3.16Å; V284-V288 WeakPolarHBondContact O-CG2 3.23Å; V284-V288 PolarHBondContact O-N 2.8Å
285M98.9Very high98.4Very high0 Ų01.6 Ų1.60%01%0.007CC..Hα-helixtrans-57.5-48.1174-173.1172.4-171.800111.9V225 C226 I229 F281 T287 V288 M289 N340 L359 A361V225-M285 HydrophobicContact CG1-CG 4.2Å; C226-M285 HydrophobicContact CB-CE 3.63Å; I229-M285 HydrophobicContact CG1-CB 3.8Å; I229-M285 HydrophobicContact CG1-CG 4.15Å; F281-M285 WeakPolarHBondContact O-CB 3.48Å; F281-M285 PolarHBondContact O-N 2.9Å; M285-T287 PolarHBondContact O-N 2.77Å; M285-V288 PolarHBondContact O-N 3.01Å; M285-V288 VanDerWaalsContact O-N 3.14Å; M285-M289 HydrophobicContact CE-CE 3.18Å; M285-M289 HydrophobicContact CG-CE 4.08Å; M285-M289 HydrophobicContact CG-CG 4.31Å; M285-M289 WeakPolarHBondContact O-CG 3.38Å; M285-M289 PolarHBondContact O-N 2.84Å; M285-M289 HydrophobicContact SD-CE 4.48Å; M285-N340 WeakPolarHBondContact CB-OD1 3.39Å; M285-N340 HydrophobicContact SD-CB 4.21Å; M285-N340 PolarHBondContact SD-OD1 3Å; M285-L359 HydrophobicContact CE-CB 3.37Å; M285-L359 HydrophobicContact CE-CD1 4.37Å; M285-L359 HydrophobicContact CE-CD2 3.76Å; M285-L359 HydrophobicContact CE-CG 4.02Å; M285-L359 HydrophobicContact SD-CB 4.24Å; M285-A361 HydrophobicContact SD-CB 3.76Å
286C98.9Very high98.5Very high0 Ų00.7 Ų0.70%00%0.003CC..Hα-helixtrans-54.3-44176.3-1720000111.4Y183 A282 A283 V284 V288 M289 R290 T296 V298Y183-C286 HydrophobicContact CD1-CB 4.1Å; Y183-C286 HydrophobicContact CE1-CB 3.77Å; A282-C286 VanDerWaalsContact O-CB 3.3Å; A282-C286 WeakPolarHBondContact O-CB 2.93Å; A282-C286 PolarHBondContact O-N 2.71Å; A283-C286 PolarHBondContact O-N 2.78Å; V284-C286 PolarHBondContact O-N 3.38Å; C286-V288 PolarHBondContact O-N 3.31Å; C286-M289 PolarHBondContact O-N 3.1Å; C286-R290 WeakPolarHBondContact O-CB 3.48Å; C286-R290 VanDerWaalsContact O-CG 3.25Å; C286-R290 WeakPolarHBondContact O-CG 3.1Å; C286-R290 PolarHBondContact O-N 3.48Å; C286-R290 PolarHBondContact SG-NE 2.65Å; C286-R290 VanDerWaalsContact SG-NE 3.38Å; C286-T296 HydrophobicContact CB-CG2 4.23Å; C286-V298 HydrophobicContact CB-CG2 3.69Å
287T98.9Very high98.6Very high0 Ų01.4 Ų1.40%01%0.006CC..Hα-helixtrans-60.3-47.9178.4-54.40000111.3Y183 Q185 I190 S258 L262 A283 V284 M285 C291Y183-T287 WeakPolarHBondContact CA-OG1 3.47Å; Y183-T287 WeakPolarHBondContact O-CG2 3.1Å; Y183-T287 PolarHBondContact O-OG1 2.91Å; Q185-T287 HydrophobicContact CB-CG2 4.05Å; I190-T287 HydrophobicContact CG2-CG2 4.32Å; S258-T287 WeakPolarHBondContact CB-OG1 3.37Å; S258-T287 PolarHBondContact OG-OG1 3.49Å; L262-T287 HydrophobicContact CD1-CG2 3.91Å; A283-T287 PolarHBondContact O-N 2.85Å; A283-T287 PolarHBondContact O-OG1 2.79Å; V284-T287 WeakPolarHBondContact O-CB 3.43Å; V284-T287 PolarHBondContact O-N 2.91Å; V284-T287 VanDerWaalsContact O-N 3.16Å; M285-T287 PolarHBondContact O-N 2.77Å; T287-C291 VanDerWaalsContact O-CB 3.24Å; T287-C291 WeakPolarHBondContact O-CB 3.35Å; T287-C291 PolarHBondContact O-N 2.77Å
288V98.9Very high98.7Very high0 Ų01.5 Ų1.50%01%0.007CC..Hα-helixtrans-64.5-46.1-179.7177.50000111C194 L197 V225 I229 L262 V284 M285 C286 C291 L292C194-V288 HydrophobicContact CB-CG1 4.23Å; L197-V288 HydrophobicContact CD1-CG2 4.11Å; V225-V288 HydrophobicContact CG1-CB 4.05Å; V225-V288 HydrophobicContact CG1-CG1 3.72Å; V225-V288 HydrophobicContact CG2-CG1 3.89Å; I229-V288 HydrophobicContact CD1-CG2 4.14Å; L262-V288 HydrophobicContact CD1-CG2 4.37Å; L262-V288 HydrophobicContact CD2-CG2 4.24Å; V284-V288 WeakPolarHBondContact O-CG2 3.23Å; V284-V288 PolarHBondContact O-N 2.8Å; M285-V288 PolarHBondContact O-N 3.01Å; M285-V288 VanDerWaalsContact O-N 3.14Å; C286-V288 PolarHBondContact O-N 3.31Å; V288-C291 WeakPolarHBondContact O-CB 3.48Å; V288-C291 PolarHBondContact O-N 3.41Å; V288-L292 HydrophobicContact CG1-CD1 4.01Å; V288-L292 VanDerWaalsContact O-CG 3.32Å; V288-L292 WeakPolarHBondContact O-CG 3.09Å; V288-L292 PolarHBondContact O-N 2.86Å
289M98.9Very high98.8Very high0 Ų01.5 Ų1.50%01%0.007CC..Hα-helixtrans-63.1-46.1179.6-64.1-59.8-167.500112.5V225 M285 C286 C291 L292 G293 I294 T296V225-M289 HydrophobicContact CB-CE 3.76Å; V225-M289 HydrophobicContact CB-SD 4.16Å; V225-M289 HydrophobicContact CG1-CE 3.72Å; V225-M289 HydrophobicContact CG1-SD 4.06Å; V225-M289 HydrophobicContact CG2-SD 4.34Å; M285-M289 HydrophobicContact CE-CE 3.18Å; M285-M289 HydrophobicContact CG-CE 4.08Å; M285-M289 HydrophobicContact CG-CG 4.31Å; M285-M289 WeakPolarHBondContact O-CG 3.38Å; M285-M289 PolarHBondContact O-N 2.84Å; M285-M289 HydrophobicContact SD-CE 4.48Å; C286-M289 PolarHBondContact O-N 3.1Å; M289-C291 VanDerWaalsContact C-N 3.32Å; M289-C291 PolarHBondContact O-N 2.98Å; M289-L292 PolarHBondContact O-N 2.88Å; M289-G293 PolarHBondContact O-N 2.8Å; M289-G293 VanDerWaalsContact O-N 3.09Å; M289-I294 CarbonylContact C-O 3.54Å; M289-I294 HydrophobicContact CB-CB 4.27Å; M289-I294 PolarHBondContact O-N 3.03Å; M289-I294 HydrophobicContact SD-CD1 4.01Å; M289-T296 HydrophobicContact CB-CG2 4.17Å; M289-T296 WeakPolarHBondContact CB-OG1 3.49Å; M289-T296 HydrophobicContact CG-CG2 4.4Å
290R98.9Very high98.9Very high5 Ų51.4 Ų1.42%0.0191%0.006CC..Hα-helixtrans-60.2-42.9175.8-71.9-170.5179.9-170.8-2111.5E159 Y160 N163 Q185 C286 L292 G293 T296E159-R290 PolarHBondContact O-NH1 2.93Å; E159-R290 VanDerWaalsContact O-NH1 3.12Å; E159-R290 PolarHBondContact O-NH2 3.47Å; E159-R290 VanDerWaalsContact O-NH2 3.12Å; Y160-R290 VanDerWaalsContact O-CG 3.31Å; Y160-R290 WeakPolarHBondContact O-CG 3.44Å; Y160-R290 PolarHBondContact O-NE 2.9Å; N163-R290 PolarHBondContact O-NH1 2.91Å; Q185-R290 HydrophobicContact CB-CB 4.39Å; Q185-R290 HydrophobicContact CG-CB 4.02Å; C286-R290 WeakPolarHBondContact O-CB 3.48Å; C286-R290 VanDerWaalsContact O-CG 3.25Å; C286-R290 WeakPolarHBondContact O-CG 3.1Å; C286-R290 PolarHBondContact O-N 3.48Å; C286-R290 PolarHBondContact SG-NE 2.65Å; C286-R290 VanDerWaalsContact SG-NE 3.38Å; R290-L292 VanDerWaalsContact C-N 3.31Å; R290-L292 PolarHBondContact O-N 2.79Å; R290-G293 PolarHBondContact O-N 3.5Å; R290-T296 PolarHBondContact NE-O 3.42Å; R290-T296 PolarHBondContact NH2-O 2.67Å
291C98.9Very high98.9Very high1 Ų11.4 Ų1.41%0.0071%0.006CC..Hα-helixtrans-59.3-41.8176.4-163.20000112Q185 I191 C194 T287 V288 M289 G293Q185-C291 HydrophobicContact CB-CB 3.9Å; Q185-C291 PolarHBondContact O-SG 2.94Å; Q185-C291 VanDerWaalsContact O-SG 3.37Å; I191-C291 VanDerWaalsContact CA-SG 3.52Å; C194-C291 HydrophobicContact CB-CB 4.43Å; T287-C291 VanDerWaalsContact O-CB 3.24Å; T287-C291 WeakPolarHBondContact O-CB 3.35Å; T287-C291 PolarHBondContact O-N 2.77Å; V288-C291 WeakPolarHBondContact O-CB 3.48Å; V288-C291 PolarHBondContact O-N 3.41Å; M289-C291 VanDerWaalsContact C-N 3.32Å; M289-C291 PolarHBondContact O-N 2.98Å; C291-G293 PolarHBondContact O-N 2.83Å
292L98.9Very high98.7Very high0 Ų01.4 Ų1.40%01%0.006CC..Hα-helixtrans-75.3-10177.9-64.9175.1000113.5F140 C194 L195 L198 V221 V225 V288 M289 R290F140-L292 WeakPolarHBondContact CB-O 3.24Å; F140-L292 HydrophobicContact CD2-CB 4.45Å; F140-L292 WeakPolarHBondContact CD2-O 3.1Å; F140-L292 PolarHBondContact N-O 2.9Å; C194-L292 HydrophobicContact CB-CD2 4.37Å; L195-L292 HydrophobicContact CD2-CD2 4.01Å; L198-L292 HydrophobicContact CD1-CD1 4.24Å; L198-L292 HydrophobicContact CD1-CD2 4.36Å; L198-L292 HydrophobicContact CD2-CD1 4.49Å; V221-L292 HydrophobicContact CG1-CD1 3.87Å; V225-L292 HydrophobicContact CG2-CD1 4.15Å; V288-L292 HydrophobicContact CG1-CD1 4.01Å; V288-L292 VanDerWaalsContact O-CG 3.32Å; V288-L292 WeakPolarHBondContact O-CG 3.09Å; V288-L292 PolarHBondContact O-N 2.86Å; M289-L292 PolarHBondContact O-N 2.88Å; R290-L292 VanDerWaalsContact C-N 3.31Å; R290-L292 PolarHBondContact O-N 2.79Å
293G98.8Very high98.4Very high0 Ų01.8 Ų1.80%01%0.008CC..THydrogen-bonded Turntrans92.113.4179.100000115.1P142 M289 R290 C291P142-G293 WeakPolarHBondContact CD-O 3.34Å; M289-G293 PolarHBondContact O-N 2.8Å; M289-G293 VanDerWaalsContact O-N 3.09Å; R290-G293 PolarHBondContact O-N 3.5Å; C291-G293 PolarHBondContact O-N 2.83Å
294I98.9Very high98.2Very high0 Ų01.9 Ų1.90%01%0.009CC..  trans-87121.7172-56.9-179.9000107.6F140 V149 P218 V221 M289 T296 C342 M344F140-I294 HydrophobicContact CB-CG1 4.41Å; F140-I294 HydrophobicContact CD2-CD1 3.94Å; F140-I294 HydrophobicContact CD2-CG1 3.51Å; F140-I294 HydrophobicContact CE2-CD1 3.77Å; F140-I294 HydrophobicContact CE2-CG1 3.91Å; F140-I294 HydrophobicContact CG-CG1 3.96Å; F140-I294 HydrophobicContact CZ-CD1 4.37Å; V149-I294 HydrophobicContact CG1-CG1 4.3Å; V149-I294 HydrophobicContact CG1-CG2 4.38Å; P218-I294 HydrophobicContact CB-CD1 4.18Å; V221-I294 HydrophobicContact CG1-CD1 4.22Å; M289-I294 CarbonylContact C-O 3.54Å; M289-I294 HydrophobicContact CB-CB 4.27Å; M289-I294 PolarHBondContact O-N 3.03Å; M289-I294 HydrophobicContact SD-CD1 4.01Å; I294-T296 PolarHBondContact O-N 2.79Å; I294-T296 PolarHBondContact O-OG1 3.38Å; I294-C342 HydrophobicContact CG2-CB 3.97Å; I294-M344 HydrophobicContact CG2-CE 4.31Å
295P98.9Very high97.8Very high0 Ų02 Ų20%01%0.01CC..  trans-64122.6177-1829.5000110.6P142 L151 Y160 V161 C342 W343P142-P295 HydrophobicContact CB-CG 3.62Å; P142-P295 HydrophobicContact CG-CG 4.23Å; L151-P295 HydrophobicContact CB-CG 4.33Å; L151-P295 HydrophobicContact CD2-CB 3.96Å; L151-P295 HydrophobicContact CD2-CG 4.23Å; Y160-P295 WeakPolarHBondContact O-CA 3.48Å; V161-P295 HydrophobicContact CG2-CB 3.94Å; V161-P295 HydrophobicContact CG2-CG 3.89Å; P295-C342 WeakPolarHBondContact O-CA 3.32Å; P295-W343 HydrophobicContact CB-CB 3.99Å; P295-W343 HydrophobicContact CG-CB 4.3Å; P295-W343 PolarHBondContact O-N 3.38Å
296T98.9Very high97.2Very high0 Ų03.1 Ų3.10%02%0.015CC..EExtended strand (participates in β ladder)trans-139.4142.3-173-59.70000112Y160 C286 M289 R290 I294 N340 E341 C342Y160-T296 PolarHBondContact O-N 3.36Å; C286-T296 HydrophobicContact CB-CG2 4.23Å; M289-T296 HydrophobicContact CB-CG2 4.17Å; M289-T296 WeakPolarHBondContact CB-OG1 3.49Å; M289-T296 HydrophobicContact CG-CG2 4.4Å; R290-T296 PolarHBondContact NE-O 3.42Å; R290-T296 PolarHBondContact NH2-O 2.67Å; I294-T296 PolarHBondContact O-N 2.79Å; I294-T296 PolarHBondContact O-OG1 3.38Å; T296-N340 HydrophobicContact CG2-CB 4.04Å; T296-E341 VanDerWaalsContact CA-O 3.28Å; T296-E341 WeakPolarHBondContact CA-O 3.44Å; T296-C342 PolarHBondContact OG1-SG 2.9Å
297R98.9Very high96.5Very high16 Ų163.4 Ų3.46%0.062%0.017CC..EExtended strand (participates in β ladder)trans-130153.9171.561.5-175.8-175.7176.63.9111.3Y160 I299 N340 E341 W356Y160-R297 HydrophobicContact CD1-CB 3.84Å; Y160-R297 HydrophobicContact CE1-CB 3.82Å; Y160-R297 HydrophobicContact CE1-CG 4.37Å; Y160-R297 PolarHBondContact OH-NH1 2.85Å; R297-I299 HydrophobicContact CG-CD1 3.83Å; R297-N340 WeakPolarHBondContact O-CA 3.16Å; R297-E341 HydrophobicContact CG-CB 3.91Å; R297-E341 IonicContact CZ-OE2 2.67Å; R297-E341 PolarHBondContact N-O 3.45Å; R297-E341 IonicContact NE-OE2 3.74Å; R297-E341 PolarHBondContact NE-OE2 3.49Å; R297-E341 IonicContact NH2-OE1 3.93Å; R297-E341 IonicContact NH2-OE2 2.84Å; R297-E341 PolarHBondContact NH2-OE2 2.91Å; R297-E341 PolarHBondContact O-N 3.12Å; R297-W356 HydrophobicContact CG-CE3 4.49Å; R297-W356 HydrophobicContact CG-CH2 4.13Å; R297-W356 HydrophobicContact CG-CZ3 4.07Å
298V98.9Very high95.5Very high5 Ų56.1 Ų6.13%0.033%0.033CC..EExtended strand (participates in β ladder)trans-93131.2176.1177.30000108.5I168 Y183 A282 C286 V338 T429I168-V298 HydrophobicContact CG1-CG1 4.22Å; I168-V298 HydrophobicContact CG2-CG1 4.11Å; Y183-V298 HydrophobicContact CE1-CG2 3.96Å; Y183-V298 WeakPolarHBondContact OH-CG2 3.48Å; A282-V298 HydrophobicContact CB-CG1 4.18Å; C286-V298 HydrophobicContact CB-CG2 3.69Å; V298-V338 HydrophobicContact CG1-CG1 3.27Å; V298-T429 PolarHBondContact O-OG1 2.74Å
299I98.9Very high94.5Very high0 Ų09.8 Ų9.80%05%0.053CC..EExtended strand (participates in β ladder)trans-115132-178.1-55.4-50000109R297 V338 W339 E341 I427 S428 T429 I440R297-I299 HydrophobicContact CG-CD1 3.83Å; I299-V338 CarbonylContact O-C 3.55Å; I299-V338 VanDerWaalsContact O-CA 3.23Å; I299-V338 WeakPolarHBondContact O-CA 3.41Å; I299-V338 VanDerWaalsContact O-CG1 3.28Å; I299-V338 WeakPolarHBondContact O-CG1 3.45Å; I299-W339 HydrophobicContact CB-CG 4.37Å; I299-W339 HydrophobicContact CG2-CZ2 4.02Å; I299-W339 PolarHBondContact N-O 2.87Å; I299-W339 PolarHBondContact O-N 3.26Å; I299-E341 HydrophobicContact CD1-CB 4.39Å; I299-E341 HydrophobicContact CD1-CG 4.19Å; I299-E341 HydrophobicContact CG1-CB 4.07Å; I299-E341 HydrophobicContact CG1-CG 3.66Å; I299-I427 HydrophobicContact CG2-CG2 3.35Å; I299-S428 WeakPolarHBondContact CA-O 3.48Å; I299-T429 HydrophobicContact CD1-CG2 4.31Å; I299-I440 HydrophobicContact CD1-CD1 3.54Å; I299-I440 HydrophobicContact CG1-CD1 4.38Å; I299-I440 HydrophobicContact CG2-CD1 4.36Å
300T98.8Very high93.7Very high1 Ų111.1 Ų11.11%0.0067%0.067CC..EExtended strand (participates in β ladder)trans-108.2127168.6-59.10000109.5Y169 F302 F336 H337 V338 I427 S428Y169-T300 PolarHBondContact N-OG1 3.38Å; Y169-T300 WeakPolarHBondContact O-CB 3.34Å; Y169-T300 WeakPolarHBondContact O-CG2 3.37Å; Y169-T300 PolarHBondContact O-OG1 3.38Å; T300-F302 HydrophobicContact CG2-CD2 4.16Å; T300-F302 HydrophobicContact CG2-CE1 4.2Å; T300-F302 HydrophobicContact CG2-CE2 3.65Å; T300-F302 HydrophobicContact CG2-CZ 3.67Å; T300-F336 HydrophobicContact CG2-CB 3.82Å; T300-F336 HydrophobicContact CG2-CD2 3.96Å; T300-F336 HydrophobicContact CG2-CG 4.21Å; T300-H337 CarbonylContact C-O 3.55Å; T300-H337 WeakPolarHBondContact CA-O 3.28Å; T300-V338 HydrophobicContact CG2-CG2 4.26Å; T300-I427 CarbonylContact O-C 3.59Å; T300-I427 VanDerWaalsContact O-CA 3.28Å; T300-I427 WeakPolarHBondContact O-CA 3.38Å; T300-S428 PolarHBondContact N-O 3.37Å; T300-S428 PolarHBondContact O-N 3.45Å
301N98.3Very high93Very high0 Ų012.8 Ų12.80%08%0.076CC..EExtended strand (participates in β ladder)trans-106.6124.2169.417932.7000110S304 F336 H337 W339 M398 G424 N425 I427N301-S304 WeakPolarHBondContact ND2-CA 3.43Å; N301-S304 VanDerWaalsContact ND2-CB 3.26Å; N301-S304 WeakPolarHBondContact ND2-CB 3.33Å; N301-S304 PolarHBondContact ND2-OG 3.02Å; N301-F336 CarbonylContact O-C 3.54Å; N301-F336 WeakPolarHBondContact O-CA 3.42Å; N301-F336 WeakPolarHBondContact O-CB 3.36Å; N301-H337 PolarHBondContact N-O 2.71Å; N301-H337 PolarHBondContact O-N 2.87Å; N301-W339 HydrophobicContact CB-CE3 4.42Å; N301-W339 HydrophobicContact CB-CH2 3.27Å; N301-W339 HydrophobicContact CB-CZ2 4.13Å; N301-W339 HydrophobicContact CB-CZ3 3.44Å; N301-W339 VanDerWaalsContact CB-CZ3 3.44Å; N301-M398 PolarHBondContact ND2-O 2.89Å; N301-G424 WeakPolarHBondContact OD1-CA 3.15Å; N301-N425 PolarHBondContact OD1-N 2.75Å; N301-I427 HydrophobicContact CB-CG1 4.41Å; N301-I427 WeakPolarHBondContact OD1-CG1 3.4Å
302F95.3Very high92.6Very high0 Ų012.8 Ų12.80%08%0.076CC..EExtended strand (participates in β ladder)trans-90.6147.3176.2-64.8-89.2000110.9K173 I176 T300 S304 F336 N425 F426K173-F302 HydrophobicContact CB-CB 4.08Å; I176-F302 HydrophobicContact CB-CZ 4.18Å; I176-F302 HydrophobicContact CD1-CD2 4.1Å; I176-F302 HydrophobicContact CD1-CE2 3.71Å; I176-F302 HydrophobicContact CD1-CZ 4.16Å; I176-F302 HydrophobicContact CG1-CD2 4.35Å; I176-F302 HydrophobicContact CG1-CE1 4.17Å; I176-F302 HydrophobicContact CG1-CE2 3.78Å; I176-F302 HydrophobicContact CG1-CZ 3.69Å; I176-F302 HydrophobicContact CG2-CE2 4.07Å; I176-F302 HydrophobicContact CG2-CZ 3.76Å; T300-F302 HydrophobicContact CG2-CD2 4.16Å; T300-F302 HydrophobicContact CG2-CE1 4.2Å; T300-F302 HydrophobicContact CG2-CE2 3.65Å; T300-F302 HydrophobicContact CG2-CZ 3.67Å; F302-S304 VanDerWaalsContact C-N 3.32Å; F302-S304 PolarHBondContact O-N 3.24Å; F302-F336 HydrophobicContact CD1-CB 3.65Å; F302-F336 HydrophobicContact CE1-CB 3.87Å; F302-F336 HydrophobicContact CE1-CG 4.37Å; F302-F336 HydrophobicContact CG-CB 4.28Å; F302-N425 WeakPolarHBondContact CB-O 3.42Å; F302-N425 PolarHBondContact N-O 3.34Å; F302-N425 PolarHBondContact O-N 2.53Å; F302-F426 HydrophobicContact CD2-CB 4.03Å; F302-F426 WeakPolarHBondContact CD2-O 2.98Å
303D93Very high92.1Very high10 Ų1014.5 Ų14.55%0.0539%0.085CC..EExtended strand (participates in β ladder)trans52.251.6-171.5-57.2-44.2000111.3K173 G305 I333 W334 N335 S422 V423 G424K173-D303 WeakPolarHBondContact CD-OD2 3.48Å; K173-D303 WeakPolarHBondContact CE-OD2 3.48Å; K173-D303 WeakPolarHBondContact CG-OD2 3.38Å; K173-D303 IonicContact NZ-OD2 3.25Å; K173-D303 PolarHBondContact NZ-OD2 3.38Å; D303-G305 PolarHBondContact O-N 2.98Å; D303-I333 HydrophobicContact CB-CG2 3.96Å; D303-W334 CarbonylContact C-O 3.57Å; D303-W334 VanDerWaalsContact CA-O 3.22Å; D303-W334 WeakPolarHBondContact CA-O 3.25Å; D303-W334 PolarHBondContact N-O 2.88Å; D303-N335 PolarHBondContact N-O 2.84Å; D303-S422 WeakPolarHBondContact CB-O 3.33Å; D303-V423 VanDerWaalsContact O-CA 3.3Å; D303-V423 WeakPolarHBondContact O-CA 3.04Å; D303-G424 PolarHBondContact O-N 2.96Å
304S94.5Very high91.6Very high2 Ų214.6 Ų14.61%0.0149%0.085CC..EExtended strand (participates in β ladder)trans-76126.8-175.6-167.10000110.6N301 F302 I333 W334 H337N301-S304 WeakPolarHBondContact ND2-CA 3.43Å; N301-S304 VanDerWaalsContact ND2-CB 3.26Å; N301-S304 WeakPolarHBondContact ND2-CB 3.33Å; N301-S304 PolarHBondContact ND2-OG 3.02Å; F302-S304 VanDerWaalsContact C-N 3.32Å; F302-S304 PolarHBondContact O-N 3.24Å; S304-I333 CarbonylContact O-C 3.58Å; S304-I333 WeakPolarHBondContact O-CA 3.17Å; S304-W334 PolarHBondContact N-O 3.16Å; S304-W334 PolarHBondContact O-N 2.94Å; S304-H337 VanDerWaalsContact CB-CB 3.41Å; S304-H337 WeakPolarHBondContact OG-CB 3.42Å
305G90.3Very high91.1Very high1 Ų115.8 Ų15.81%0.019%0.091CC..EExtended strand (participates in β ladder)trans-72.8139.5177.300000111.9D303 M398D303-G305 PolarHBondContact O-N 2.98Å; G305-M398 PolarHBondContact N-O 3.44Å; G305-M398 VanDerWaalsContact O-CA 3.29Å; G305-M398 WeakPolarHBondContact O-CA 3.22Å; G305-M398 WeakPolarHBondContact O-CG 3.19Å
306H85.9Confident90.6Very high25 Ų2516.1 Ų16.112%0.1169%0.093CC..EExtended strand (participates in β ladder)trans-125.190.2167.3-173.3-157.2000108.1D331 T332 W334 F394H306-D331 WeakPolarHBondContact O-CA 3.47Å; H306-D331 WeakPolarHBondContact O-CB 3.26Å; H306-T332 WeakPolarHBondContact CB-O 3.27Å; H306-T332 PolarHBondContact N-O 3.29Å; H306-T332 PolarHBondContact O-N 2.73Å; H306-W334 AromaticContact ND1-NE1 3.98Å; H306-F394 AromaticContact CD2-CE2 3.6Å; H306-F394 AromaticContact CD2-CZ 3.89Å; H306-F394 AromaticContact NE2-CE2 3.95Å
307D83.7Confident90.2Very high6 Ų617.3 Ų17.33%0.03210%0.097CC..  trans-90.8113.3178.5171.710.1000109.7D309 G310 N311 L312D307-D309 PolarHBondContact OD1-N 2.76Å; D307-D309 VanDerWaalsContact OD1-N 3.1Å; D307-G310 WeakPolarHBondContact OD1-CA 3.4Å; D307-G310 PolarHBondContact OD1-N 3.29Å; D307-G310 WeakPolarHBondContact OD2-CA 3.3Å; D307-G310 PolarHBondContact OD2-N 3.07Å; D307-N311 PolarHBondContact OD1-N 2.86Å; D307-N311 PolarHBondContact OD2-N 2.93Å; D307-L312 WeakPolarHBondContact OD2-CA 3.48Å; D307-L312 PolarHBondContact OD2-N 2.82Å
308T78.1Confident89.8Confident56 Ų5616.5 Ų16.534%0.34410%0.095SC..SBendtrans-93.2-16-174.861.40000113.6K330 D331T308-K330 VanDerWaalsContact CG2-O 3.23Å; T308-K330 WeakPolarHBondContact CG2-O 3.49Å; T308-K330 PolarHBondContact OG1-O 3.14Å; T308-D331 WeakPolarHBondContact CB-OD1 3.06Å; T308-D331 PolarHBondContact N-OD1 2.96Å; T308-D331 PolarHBondContact OG1-OD1 3.27Å
309D79.6Confident89.4Confident78 Ų7816.9 Ų16.942%0.41710%0.096SC..SBendtrans-108.7-5.6-179.285.19000113.1D307 N311 R468D307-D309 PolarHBondContact OD1-N 2.76Å; D307-D309 VanDerWaalsContact OD1-N 3.1Å; D309-N311 VanDerWaalsContact CG-ND2 3.25Å; D309-N311 WeakPolarHBondContact OD1-CB 2.94Å; D309-N311 PolarHBondContact OD1-N 3.32Å; D309-N311 PolarHBondContact OD1-ND2 3.29Å; D309-N311 PolarHBondContact OD1-OD1 2.87Å; D309-N311 PolarHBondContact OD2-ND2 3.01Å; D309-R468 PolarHBondContact O-NH2 2.97Å
310G80.9Confident89Confident28 Ų2820.6 Ų20.629%0.28912%0.116SC..SBendtrans73.921.4172.800000114.2D307 R468D307-G310 WeakPolarHBondContact OD1-CA 3.4Å; D307-G310 PolarHBondContact OD1-N 3.29Å; D307-G310 WeakPolarHBondContact OD2-CA 3.3Å; D307-G310 PolarHBondContact OD2-N 3.07Å; G310-R468 PolarHBondContact O-NH2 3Å
311N85.4Confident88.5Confident39 Ų3922.5 Ų22.521%0.20913%0.128CC..SBendtrans-89.5-2.2-175.673.719.8000113.7D307 D309 I313D307-N311 PolarHBondContact OD1-N 2.86Å; D307-N311 PolarHBondContact OD2-N 2.93Å; D309-N311 VanDerWaalsContact CG-ND2 3.25Å; D309-N311 WeakPolarHBondContact OD1-CB 2.94Å; D309-N311 PolarHBondContact OD1-N 3.32Å; D309-N311 PolarHBondContact OD1-ND2 3.29Å; D309-N311 PolarHBondContact OD1-OD1 2.87Å; D309-N311 PolarHBondContact OD2-ND2 3.01Å; N311-I313 VanDerWaalsContact C-N 3.28Å; N311-I313 VanDerWaalsContact OD1-CA 3.25Å; N311-I313 WeakPolarHBondContact OD1-CA 3.38Å; N311-I313 WeakPolarHBondContact OD1-CB 3.1Å; N311-I313 PolarHBondContact OD1-N 3.37Å; N311-I313 PolarHBondContact OD1-O 3.01Å
312L89.8Confident88Confident1 Ų122.5 Ų22.51%0.00513%0.128CC..SBendtrans64.424.2-174.4-55178.7000114.7D307 F396 A401 D402 F457 A460 L461 L464D307-L312 WeakPolarHBondContact OD2-CA 3.48Å; D307-L312 PolarHBondContact OD2-N 2.82Å; L312-F396 HydrophobicContact CD1-CD1 4.21Å; L312-F396 HydrophobicContact CD1-CE1 4.07Å; L312-F396 HydrophobicContact CD2-CD1 3.98Å; L312-A401 WeakPolarHBondContact O-CA 3.24Å; L312-D402 PolarHBondContact O-N 2.94Å; L312-F457 HydrophobicContact CB-CE2 3.96Å; L312-F457 HydrophobicContact CB-CZ 3.89Å; L312-F457 HydrophobicContact CD1-CE2 4.17Å; L312-F457 HydrophobicContact CD1-CZ 4.33Å; L312-A460 HydrophobicContact CD1-CB 4.31Å; L312-L461 HydrophobicContact CD1-CB 4.24Å; L312-L461 HydrophobicContact CD1-CD1 4.31Å; L312-L464 HydrophobicContact CD1-CD1 3.69Å; L312-L464 HydrophobicContact CD2-CD1 3.89Å; L312-L464 HydrophobicContact CG-CD1 3.61Å
313I88.7Confident87.7Confident37 Ų3727.2 Ų27.219%0.1915%0.146CC..EExtended strand (participates in β ladder)trans-130.3129.8179.8-56.9174.7000108.4N311 D402 M404N311-I313 VanDerWaalsContact C-N 3.28Å; N311-I313 VanDerWaalsContact OD1-CA 3.25Å; N311-I313 WeakPolarHBondContact OD1-CA 3.38Å; N311-I313 WeakPolarHBondContact OD1-CB 3.1Å; N311-I313 PolarHBondContact OD1-N 3.37Å; N311-I313 PolarHBondContact OD1-O 3.01Å; I313-D402 CarbonylContact C-O 3.55Å; I313-D402 VanDerWaalsContact CA-O 3.27Å; I313-D402 WeakPolarHBondContact CA-O 3.44Å; I313-M404 HydrophobicContact CG2-CB 4Å; I313-M404 HydrophobicContact CG2-CG 3.38Å
314I86.9Confident87.5Confident1 Ų127 Ų271%0.00514%0.144CC..EExtended strand (participates in β ladder)trans-109122175.8-62.5172000109D331 I333 A401 D402 C403 M404 V423I314-D331 HydrophobicContact CB-CB 4.32Å; I314-D331 HydrophobicContact CG1-CB 4.33Å; I314-D331 HydrophobicContact CG2-CB 3.81Å; I314-I333 HydrophobicContact CB-CG1 4.42Å; I314-I333 HydrophobicContact CD1-CG1 4.03Å; I314-I333 HydrophobicContact CG2-CD1 4.27Å; I314-I333 HydrophobicContact CG2-CG1 3.71Å; I314-A401 HydrophobicContact CD1-CB 3.75Å; I314-A401 HydrophobicContact CG1-CB 3.96Å; I314-D402 PolarHBondContact N-O 3.35Å; I314-C403 WeakPolarHBondContact O-CA 3.37Å; I314-M404 PolarHBondContact O-N 2.88Å; I314-V423 HydrophobicContact CD1-CG2 4.23Å
315D88.6Confident87.1Confident26 Ų2628 Ų2814%0.13915%0.149CC..EExtended strand (participates in β ladder)trans-94.7120.1-178.9-68.9-45.7000112.3Y317 M404 W406D315-Y317 HydrophobicContact CB-CE2 3.76Å; D315-M404 WeakPolarHBondContact CA-O 3.4Å; D315-M404 WeakPolarHBondContact OD1-CB 3.41Å; D315-W406 PolarHBondContact OD1-NE1 2.59Å
316E89Confident86.4Confident7 Ų729.8 Ų29.83%0.03317%0.168CC..EExtended strand (participates in β ladder)trans-107.2129.3170.2-73.8-161.1141.800111.5Y318 M404 S405 W406 R595E316-Y318 HydrophobicContact CB-CE2 3.83Å; E316-Y318 PolarHBondContact OE2-OH 3.01Å; E316-M404 PolarHBondContact N-O 2.84Å; E316-S405 CarbonylContact O-C 3.46Å; E316-S405 WeakPolarHBondContact O-CA 3.27Å; E316-W406 PolarHBondContact O-N 3.36Å; E316-R595 IonicContact OE1-CZ 3.84Å; E316-R595 IonicContact OE1-NH1 3.29Å; E316-R595 PolarHBondContact OE1-NH1 3.03Å; E316-R595 IonicContact OE1-NH2 2.72Å; E316-R595 IonicContact OE2-NH1 2.65Å; E316-R595 PolarHBondContact OE2-NH1 3.21Å
317Y90.3Very high85.7Confident24 Ų2435.4 Ų35.49%0.09420%0.199CC..EExtended strand (participates in β ladder)trans-109132.6-177.9-62.5-87.4000112.2D315 I324 L325 K328 W406 V408 E413D315-Y317 HydrophobicContact CB-CE2 3.76Å; Y317-I324 WeakPolarHBondContact O-CA 3.07Å; Y317-L325 PolarHBondContact O-N 3.22Å; Y317-K328 HydrophobicContact CD1-CD 4.29Å; Y317-K328 HydrophobicContact CD2-CB 3.82Å; Y317-K328 HydrophobicContact CE2-CB 4.33Å; Y317-K328 HydrophobicContact CG-CB 4.05Å; Y317-K328 HydrophobicContact CG-CD 4.29Å; Y317-W406 CarbonylContact C-O 3.5Å; Y317-W406 WeakPolarHBondContact CA-O 3.29Å; Y317-W406 HydrophobicContact CD1-CB 3.61Å; Y317-W406 HydrophobicContact CD1-CG 4.17Å; Y317-W406 HydrophobicContact CE1-CB 3.82Å; Y317-W406 AromaticContact CE1-CD1 3.95Å; Y317-W406 AromaticContact CE1-CG 3.91Å; Y317-W406 HydrophobicContact CE1-CG 3.91Å; Y317-W406 HydrophobicContact CG-CB 4.47Å; Y317-V408 HydrophobicContact CD1-CG2 3.79Å; Y317-V408 HydrophobicContact CG-CG2 4.4Å; Y317-E413 HydrophobicContact CE1-CG 4.14Å
318Y91Very high85Confident0 Ų038.7 Ų38.70%021%0.213CC..EExtended strand (participates in β ladder)trans-120.7154.2178.2-64.9-99.3000110.3E316 R323 I324 W406 L407 V408 R595 L610E316-Y318 HydrophobicContact CB-CE2 3.83Å; E316-Y318 PolarHBondContact OE2-OH 3.01Å; Y318-R323 VanDerWaalsContact CA-O 3.27Å; Y318-R323 WeakPolarHBondContact CA-O 3.49Å; Y318-I324 HydrophobicContact CD1-CG1 3.85Å; Y318-I324 HydrophobicContact CE1-CD1 4.04Å; Y318-I324 HydrophobicContact CE1-CG1 3.32Å; Y318-W406 PolarHBondContact N-O 2.77Å; Y318-L407 CarbonylContact O-C 3.51Å; Y318-L407 WeakPolarHBondContact O-CA 3.35Å; Y318-V408 PolarHBondContact O-N 3.36Å; Y318-R595 PolarHBondContact OH-NH1 3.38Å; Y318-L610 HydrophobicContact CD1-CD1 4.01Å; Y318-L610 HydrophobicContact CD1-CD2 4.22Å; Y318-L610 HydrophobicContact CD2-CD2 3.77Å; Y318-L610 HydrophobicContact CE1-CD1 4.02Å; Y318-L610 HydrophobicContact CE1-CD2 3.99Å; Y318-L610 HydrophobicContact CE2-CD2 3.56Å; Y318-L610 HydrophobicContact CG-CD1 4.48Å; Y318-L610 HydrophobicContact CG-CD2 4.13Å
319D91.2Very high84.3Confident13 Ų1337.8 Ų37.87%0.0720%0.204CC..  trans-105.2-178.5166.275.616.6000112.7T321 G322 R323 L325 L407 L599D319-T321 PolarHBondContact O-N 2.78Å; D319-T321 VanDerWaalsContact O-N 3.15Å; D319-T321 WeakPolarHBondContact OD1-CA 3.46Å; D319-T321 WeakPolarHBondContact OD1-CB 3.47Å; D319-T321 PolarHBondContact OD1-N 2.71Å; D319-T321 PolarHBondContact OD1-OG1 3.44Å; D319-G322 PolarHBondContact O-N 3.16Å; D319-R323 PolarHBondContact N-O 3.33Å; D319-R323 VanDerWaalsContact N-O 3.09Å; D319-R323 WeakPolarHBondContact OD1-CG 3.4Å; D319-R323 WeakPolarHBondContact OD2-CG 3.02Å; D319-R323 IonicContact OD2-CZ 2.7Å; D319-R323 VanDerWaalsContact OD2-CZ 3.23Å; D319-R323 IonicContact OD2-NE 3.84Å; D319-R323 PolarHBondContact OD2-NE 2.99Å; D319-R323 IonicContact OD2-NH2 2.7Å; D319-R323 PolarHBondContact OD2-NH2 3.32Å; D319-L325 HydrophobicContact CB-CD1 4.26Å; D319-L325 HydrophobicContact CB-CD2 4.13Å; D319-L325 HydrophobicContact CB-CG 4.38Å; D319-L407 VanDerWaalsContact C-CD1 3.45Å; D319-L407 WeakPolarHBondContact O-CD1 3.2Å; D319-L599 WeakPolarHBondContact O-CD2 3.24Å
320N89.5Confident83.6Confident77 Ų7742.4 Ų42.441%0.41222%0.221SC..THydrogen-bonded Turntrans-64.4-14.1-178.563.2-9.3000114.4G322 N542N320-G322 VanDerWaalsContact C-N 3.31Å; N320-N542 PolarHBondContact O-ND2 3.05Å
321T88.8Confident83.3Confident41 Ų4141.4 Ų41.425%0.25221%0.208SC..THydrogen-bonded Turntrans-85.9-7.1173.372.80000112.5D319 R323 Q560D319-T321 PolarHBondContact O-N 2.78Å; D319-T321 VanDerWaalsContact O-N 3.15Å; D319-T321 WeakPolarHBondContact OD1-CA 3.46Å; D319-T321 WeakPolarHBondContact OD1-CB 3.47Å; D319-T321 PolarHBondContact OD1-N 2.71Å; D319-T321 PolarHBondContact OD1-OG1 3.44Å; T321-R323 VanDerWaalsContact C-N 3.31Å; T321-Q560 PolarHBondContact OG1-NE2 3.25Å
322G86.7Confident83.1Confident0 Ų040.3 Ų40.30%020%0.203CC..SBendtrans83.32-175.800000113.9D319 N320 S597D319-G322 PolarHBondContact O-N 3.16Å; N320-G322 VanDerWaalsContact C-N 3.31Å; G322-S597 WeakPolarHBondContact O-CB 3.33Å; G322-S597 PolarHBondContact O-OG 3.05Å
323R89.8Confident82.8Confident99 Ų9940.7 Ų40.737%0.37421%0.205SC..  trans-76.7153.3174.680.6-179.5171.9177.3-8.2111.3Y318 D319 T321Y318-R323 VanDerWaalsContact CA-O 3.27Å; Y318-R323 WeakPolarHBondContact CA-O 3.49Å; D319-R323 PolarHBondContact N-O 3.33Å; D319-R323 VanDerWaalsContact N-O 3.09Å; D319-R323 WeakPolarHBondContact OD1-CG 3.4Å; D319-R323 WeakPolarHBondContact OD2-CG 3.02Å; D319-R323 IonicContact OD2-CZ 2.7Å; D319-R323 VanDerWaalsContact OD2-CZ 3.23Å; D319-R323 IonicContact OD2-NE 3.84Å; D319-R323 PolarHBondContact OD2-NE 2.99Å; D319-R323 IonicContact OD2-NH2 2.7Å; D319-R323 PolarHBondContact OD2-NH2 3.32Å; T321-R323 VanDerWaalsContact C-N 3.31Å
324I88.7Confident82.8Confident5 Ų539.6 Ų39.63%0.02620%0.199CC..BIsolated β-bridgetrans-83137.4174.1-60.1168.8000109.5Y317 Y318 P554 R595Y317-I324 WeakPolarHBondContact O-CA 3.07Å; Y318-I324 HydrophobicContact CD1-CG1 3.85Å; Y318-I324 HydrophobicContact CE1-CD1 4.04Å; Y318-I324 HydrophobicContact CE1-CG1 3.32Å; I324-P554 HydrophobicContact CB-CB 4.21Å; I324-P554 HydrophobicContact CB-CG 3.95Å; I324-P554 HydrophobicContact CG2-CG 3.81Å; I324-R595 VanDerWaalsContact CD1-CD 3.41Å
325L86.3Confident82.9Confident23 Ų2339.6 Ų39.612%0.1220%0.199CC..  trans-93.899.1177.7-60.3179.7000110.3Y317 D319 N327 V408Y317-L325 PolarHBondContact O-N 3.22Å; D319-L325 HydrophobicContact CB-CD1 4.26Å; D319-L325 HydrophobicContact CB-CD2 4.13Å; D319-L325 HydrophobicContact CB-CG 4.38Å; L325-N327 VanDerWaalsContact C-N 3.3Å; L325-N327 PolarHBondContact O-N 2.92Å; L325-V408 HydrophobicContact CD1-CB 3.83Å; L325-V408 HydrophobicContact CD1-CG1 4.42Å; L325-V408 HydrophobicContact CD1-CG2 3.85Å
326G75Confident83.2Confident39 Ų3938.4 Ų38.440%0.40219%0.192SC..G310 helixtrans-65.8-29178.300000114K328 K329G326-K328 PolarHBondContact O-N 2.87Å; G326-K329 PolarHBondContact O-N 3.43Å
327N71.4Confident83.6Confident143 Ų14338.1 Ų38.177%0.76519%0.191SC*.G310 helixtrans-74.2-3-176.366.5-29000115.2L325L325-N327 VanDerWaalsContact C-N 3.3Å; L325-N327 PolarHBondContact O-N 2.92Å
328K68.8Low83.9Confident76 Ų7637 Ų3733%0.3319%0.186SC..G310 helixtrans-111.85.7177.1-82.3-164.2160.9-157.30113.5Y317 G326 V408 E413Y317-K328 HydrophobicContact CD1-CD 4.29Å; Y317-K328 HydrophobicContact CD2-CB 3.82Å; Y317-K328 HydrophobicContact CE2-CB 4.33Å; Y317-K328 HydrophobicContact CG-CB 4.05Å; Y317-K328 HydrophobicContact CG-CD 4.29Å; G326-K328 PolarHBondContact O-N 2.87Å; K328-V408 HydrophobicContact CD-CG2 4.15Å; K328-E413 IonicContact NZ-OE1 3.8Å; K328-E413 PolarHBondContact NZ-OE1 3.48Å
329K63.8Low84.3Confident37 Ų3737 Ų3716%0.16119%0.186CC..  trans-83.7117.3-177.2-70.6-163.9175.3-169.10111.5G326 T332 G552G326-K329 PolarHBondContact O-N 3.43Å; K329-T332 HydrophobicContact CD-CG2 3.9Å; K329-G552 PolarHBondContact NZ-O 3.16Å
330K65.8Low84.7Confident175 Ų17536.3 Ų36.376%0.76118%0.183SC*.SBendtrans-91.9-42.7155.3-72.2-173.2176.6-175.70109.8T308T308-K330 VanDerWaalsContact CG2-O 3.23Å; T308-K330 WeakPolarHBondContact CG2-O 3.49Å; T308-K330 PolarHBondContact OG1-O 3.14Å
331D74.8Confident85.1Confident6 Ų632.7 Ų32.73%0.03216%0.163CC..SBendtrans-99.7154.4178-49.7-45.1000111.9H306 T308 I314H306-D331 WeakPolarHBondContact O-CA 3.47Å; H306-D331 WeakPolarHBondContact O-CB 3.26Å; T308-D331 WeakPolarHBondContact CB-OD1 3.06Å; T308-D331 PolarHBondContact N-OD1 2.96Å; T308-D331 PolarHBondContact OG1-OD1 3.27Å; I314-D331 HydrophobicContact CB-CB 4.32Å; I314-D331 HydrophobicContact CG1-CB 4.33Å; I314-D331 HydrophobicContact CG2-CB 3.81Å
332T79.4Confident85.6Confident16 Ų1630.7 Ų30.710%0.09815%0.152CC..EExtended strand (participates in β ladder)trans-137.8148179.345.20000111.2H306 K329 W334H306-T332 WeakPolarHBondContact CB-O 3.27Å; H306-T332 PolarHBondContact N-O 3.29Å; H306-T332 PolarHBondContact O-N 2.73Å; K329-T332 HydrophobicContact CD-CG2 3.9Å; T332-W334 PolarHBondContact OG1-NE1 2.82Å; T332-W334 VanDerWaalsContact OG1-NE1 3.09Å
333I84.3Confident86.2Confident9 Ų933.7 Ų33.75%0.04616%0.163CC..EExtended strand (participates in β ladder)trans-104.4110.9163.8-57.5-178000106.5D303 S304 I314 C403 V423 G552D303-I333 HydrophobicContact CB-CG2 3.96Å; S304-I333 CarbonylContact O-C 3.58Å; S304-I333 WeakPolarHBondContact O-CA 3.17Å; I314-I333 HydrophobicContact CB-CG1 4.42Å; I314-I333 HydrophobicContact CD1-CG1 4.03Å; I314-I333 HydrophobicContact CG2-CD1 4.27Å; I314-I333 HydrophobicContact CG2-CG1 3.71Å; I333-C403 HydrophobicContact CD1-CB 3.92Å; I333-V423 HydrophobicContact CD1-CG2 4.04Å; I333-V423 HydrophobicContact CG1-CG2 4.48Å; I333-G552 WeakPolarHBondContact O-CA 3.25Å
334W89.9Confident86.6Confident15 Ų1529 Ų296%0.05715%0.145CC..EExtended strand (participates in β ladder)trans-76.1139.7177.7-69.433.8000108.7W242 C278 D303 S304 H306 T332 F336 H337 T362 Q364 H550 D551W242-W334 AromaticContact CE2-CH2 3.94Å; W242-W334 AromaticContact CZ2-CH2 3.98Å; W242-W334 HydrophobicContact CZ2-CH2 3.98Å; W242-W334 HydrophobicContact CZ2-CZ3 4.32Å; W242-W334 AromaticContact NE1-CH2 3.78Å; W242-W334 AromaticContact NE1-CZ3 3.81Å; C278-W334 HydrophobicContact CB-CZ3 4.27Å; D303-W334 CarbonylContact C-O 3.57Å; D303-W334 VanDerWaalsContact CA-O 3.22Å; D303-W334 WeakPolarHBondContact CA-O 3.25Å; D303-W334 PolarHBondContact N-O 2.88Å; S304-W334 PolarHBondContact N-O 3.16Å; S304-W334 PolarHBondContact O-N 2.94Å; H306-W334 AromaticContact ND1-NE1 3.98Å; T332-W334 PolarHBondContact OG1-NE1 2.82Å; T332-W334 VanDerWaalsContact OG1-NE1 3.09Å; W334-F336 PolarHBondContact O-N 2.92Å; W334-H337 HydrophobicContact CE3-CB 4.31Å; W334-H337 AromaticContact CE3-ND1 3.84Å; W334-H337 AromaticContact CZ3-ND1 3.82Å; W334-T362 HydrophobicContact CH2-CG2 4.41Å; W334-Q364 HydrophobicContact CZ2-CG 4.49Å; W334-H550 AromaticContact CE3-CD2 3.7Å; W334-H550 AromaticContact CE3-NE2 3.54Å; W334-H550 AromaticContact CZ3-CD2 3.77Å; W334-H550 AromaticContact CZ3-NE2 3.75Å; W334-D551 VanDerWaalsContact CD1-O 3.27Å; W334-D551 HydrophobicContact CD2-CB 3.99Å; W334-D551 HydrophobicContact CG-CB 4.3Å; W334-D551 HydrophobicContact CZ2-CB 3.98Å
335N88.7Confident87.1Confident1 Ų130.6 Ų30.61%0.00516%0.159CC..EExtended strand (participates in β ladder)trans-58.9-39.6-179.1-61.1-69.3000111.1D303 L548 L549 H550 L593D303-N335 PolarHBondContact N-O 2.84Å; N335-L548 WeakPolarHBondContact OD1-CD1 3.44Å; N335-L549 PolarHBondContact ND2-O 3.17Å; N335-H550 PolarHBondContact N-O 3.37Å; N335-H550 PolarHBondContact ND2-O 2.86Å; N335-L593 HydrophobicContact CB-CD1 3.47Å; N335-L593 VanDerWaalsContact CB-CD1 3.47Å; N335-L593 VanDerWaalsContact ND2-CD1 3.3Å; N335-L593 WeakPolarHBondContact ND2-CD1 3.46Å
336F93.5Very high87.7Confident1 Ų130.1 Ų30.10%0.00416%0.156CC..EExtended strand (participates in β ladder)trans-150.5157.2160.965.4-85.2000109.3Q170 G171 W279 T300 N301 F302 W334 V338 H550Q170-F336 HydrophobicContact CB-CE1 4.02Å; Q170-F336 HydrophobicContact CB-CE2 4.17Å; Q170-F336 HydrophobicContact CB-CZ 3.72Å; Q170-F336 HydrophobicContact CG-CE1 4.47Å; Q170-F336 HydrophobicContact CG-CE2 3.82Å; Q170-F336 HydrophobicContact CG-CZ 3.68Å; G171-F336 WeakPolarHBondContact O-CD1 3.08Å; W279-F336 HydrophobicContact CE3-CE2 4.05Å; W279-F336 HydrophobicContact CE3-CZ 4.15Å; W279-F336 HydrophobicContact CZ3-CZ 4.26Å; T300-F336 HydrophobicContact CG2-CB 3.82Å; T300-F336 HydrophobicContact CG2-CD2 3.96Å; T300-F336 HydrophobicContact CG2-CG 4.21Å; N301-F336 CarbonylContact O-C 3.54Å; N301-F336 WeakPolarHBondContact O-CA 3.42Å; N301-F336 WeakPolarHBondContact O-CB 3.36Å; F302-F336 HydrophobicContact CD1-CB 3.65Å; F302-F336 HydrophobicContact CE1-CB 3.87Å; F302-F336 HydrophobicContact CE1-CG 4.37Å; F302-F336 HydrophobicContact CG-CB 4.28Å; W334-F336 PolarHBondContact O-N 2.92Å; F336-V338 HydrophobicContact CD2-CG2 3.65Å; F336-V338 HydrophobicContact CE2-CG2 3.8Å; F336-H550 AromaticContact CD2-CE1 3.77Å; F336-H550 AromaticContact CE1-CE1 3.71Å; F336-H550 AromaticContact CE1-ND1 3.69Å; F336-H550 AromaticContact CE2-CE1 3.39Å; F336-H550 WeakPolarHBondContact CE2-CE1 3.19Å; F336-H550 AromaticContact CZ-CE1 3.35Å; F336-H550 WeakPolarHBondContact CZ-CE1 3.47Å; F336-H550 AromaticContact CZ-ND1 3.56Å; F336-H550 PolarHBondContact O-CE1 3Å; F336-H550 PolarHBondContact O-NE2 3.34Å
337H97Very high88.7Confident0 Ų036.4 Ų36.40%017%0.172CC..EExtended strand (participates in β ladder)trans-131148.6171-175.838.8000109.3C278 T300 N301 S304 W334 W339 D360 T362 Q364 M398C278-H337 VanDerWaalsContact CB-ND1 3.27Å; C278-H337 WeakPolarHBondContact CB-ND1 3.44Å; T300-H337 CarbonylContact C-O 3.55Å; T300-H337 WeakPolarHBondContact CA-O 3.28Å; N301-H337 PolarHBondContact N-O 2.71Å; N301-H337 PolarHBondContact O-N 2.87Å; S304-H337 VanDerWaalsContact CB-CB 3.41Å; S304-H337 WeakPolarHBondContact OG-CB 3.42Å; W334-H337 HydrophobicContact CE3-CB 4.31Å; W334-H337 AromaticContact CE3-ND1 3.84Å; W334-H337 AromaticContact CZ3-ND1 3.82Å; H337-W339 AromaticContact CD2-CE3 3.64Å; H337-W339 AromaticContact CD2-CZ3 3.95Å; H337-D360 IonicContact CD2-OD2 3.36Å; H337-D360 IonicContact CE1-OD1 3.88Å; H337-D360 IonicContact CE1-OD2 2.82Å; H337-D360 PolarHBondContact CE1-OD2 2.96Å; H337-D360 IonicContact NE2-OD1 2.92Å; H337-D360 IonicContact NE2-OD2 2.72Å; H337-D360 PolarHBondContact NE2-OD2 3.49Å; H337-T362 PolarHBondContact CE1-OG1 2.79Å; H337-Q364 PolarHBondContact NE2-OE1 3.27Å; H337-M398 VanDerWaalsContact CD2-SD 3.58Å
338V98.4Very high89.9Confident0 Ų033.2 Ų33.20%016%0.155CC..EExtended strand (participates in β ladder)trans-128.4127.8-173-170.30000110.3I168 C278 W279 A282 V298 I299 T300 F336I168-V338 HydrophobicContact CG2-CG1 3.87Å; I168-V338 HydrophobicContact CG2-CG2 4.13Å; C278-V338 HydrophobicContact CB-CB 4.43Å; W279-V338 HydrophobicContact CB-CB 4.15Å; W279-V338 HydrophobicContact CB-CG1 4.32Å; W279-V338 HydrophobicContact CB-CG2 3.91Å; A282-V338 HydrophobicContact CB-CB 4.34Å; A282-V338 HydrophobicContact CB-CG1 3.69Å; V298-V338 HydrophobicContact CG1-CG1 3.27Å; I299-V338 CarbonylContact O-C 3.55Å; I299-V338 VanDerWaalsContact O-CA 3.23Å; I299-V338 WeakPolarHBondContact O-CA 3.41Å; I299-V338 VanDerWaalsContact O-CG1 3.28Å; I299-V338 WeakPolarHBondContact O-CG1 3.45Å; T300-V338 HydrophobicContact CG2-CG2 4.26Å; F336-V338 HydrophobicContact CD2-CG2 3.65Å; F336-V338 HydrophobicContact CE2-CG2 3.8Å
339W98.8Very high91.3Very high0 Ų030.5 Ų30.50%014%0.144CC..EExtended strand (participates in β ladder)trans-136.7-171.9177.663.975.1000111.2I299 N301 H337 V358 D360 M398 V399 Y444I299-W339 HydrophobicContact CB-CG 4.37Å; I299-W339 HydrophobicContact CG2-CZ2 4.02Å; I299-W339 PolarHBondContact N-O 2.87Å; I299-W339 PolarHBondContact O-N 3.26Å; N301-W339 HydrophobicContact CB-CE3 4.42Å; N301-W339 HydrophobicContact CB-CH2 3.27Å; N301-W339 HydrophobicContact CB-CZ2 4.13Å; N301-W339 HydrophobicContact CB-CZ3 3.44Å; N301-W339 VanDerWaalsContact CB-CZ3 3.44Å; H337-W339 AromaticContact CD2-CE3 3.64Å; H337-W339 AromaticContact CD2-CZ3 3.95Å; W339-V358 HydrophobicContact CD2-CG1 4.39Å; W339-V358 HydrophobicContact CG-CG1 4.06Å; W339-D360 HydrophobicContact CB-CB 3.86Å; W339-M398 HydrophobicContact CE3-CE 4.01Å; W339-M398 HydrophobicContact CE3-SD 4.2Å; W339-M398 HydrophobicContact CH2-CE 4.47Å; W339-M398 HydrophobicContact CZ3-CB 4.44Å; W339-M398 HydrophobicContact CZ3-CE 3.94Å; W339-M398 HydrophobicContact CZ3-SD 3.92Å; W339-V399 HydrophobicContact CH2-CG1 3.84Å; W339-V399 HydrophobicContact CZ2-CG1 4.4Å; W339-Y444 HydrophobicContact CZ2-CD1 4.43Å; W339-Y444 AromaticContact CZ2-CE1 3.65Å; W339-Y444 HydrophobicContact CZ2-CE1 3.65Å; W339-Y444 AromaticContact CZ2-CZ 3.85Å; W339-Y444 AromaticContact NE1-CZ 3.89Å; W339-Y444 PolarHBondContact NE1-OH 3.47Å
340N98.9Very high92.9Very high0 Ų031.9 Ų31.90%016%0.157CC..EExtended strand (participates in β ladder)trans-114.9146.5177.6-63.198.9000112.4A282 M285 T296 R297 V358 L359A282-N340 WeakPolarHBondContact CA-OD1 3.46Å; A282-N340 PolarHBondContact O-ND2 2.87Å; A282-N340 PolarHBondContact O-OD1 3.48Å; M285-N340 WeakPolarHBondContact CB-OD1 3.39Å; M285-N340 HydrophobicContact SD-CB 4.21Å; M285-N340 PolarHBondContact SD-OD1 3Å; T296-N340 HydrophobicContact CG2-CB 4.04Å; R297-N340 WeakPolarHBondContact O-CA 3.16Å; N340-V358 CarbonylContact O-C 3.57Å; N340-V358 WeakPolarHBondContact O-CA 3.34Å; N340-L359 PolarHBondContact N-O 3.38Å; N340-L359 PolarHBondContact O-N 3.39Å
341E98.9Very high94.3Very high0 Ų030 Ų300%016%0.162CC..EExtended strand (participates in β ladder)trans-108.2126.6158.8-83.2177.6-16300109.4T296 R297 I299 W356 Q357 V378 Y444T296-E341 VanDerWaalsContact CA-O 3.28Å; T296-E341 WeakPolarHBondContact CA-O 3.44Å; R297-E341 HydrophobicContact CG-CB 3.91Å; R297-E341 IonicContact CZ-OE2 2.67Å; R297-E341 PolarHBondContact N-O 3.45Å; R297-E341 IonicContact NE-OE2 3.74Å; R297-E341 PolarHBondContact NE-OE2 3.49Å; R297-E341 IonicContact NH2-OE1 3.93Å; R297-E341 IonicContact NH2-OE2 2.84Å; R297-E341 PolarHBondContact NH2-OE2 2.91Å; R297-E341 PolarHBondContact O-N 3.12Å; I299-E341 HydrophobicContact CD1-CB 4.39Å; I299-E341 HydrophobicContact CD1-CG 4.19Å; I299-E341 HydrophobicContact CG1-CB 4.07Å; I299-E341 HydrophobicContact CG1-CG 3.66Å; E341-W356 HydrophobicContact CB-CB 4.31Å; E341-W356 HydrophobicContact CB-CD2 4.17Å; E341-W356 HydrophobicContact CB-CE3 3.65Å; E341-W356 HydrophobicContact CB-CG 4.49Å; E341-W356 HydrophobicContact CB-CZ3 4.33Å; E341-W356 HydrophobicContact CG-CB 4.23Å; E341-W356 WeakPolarHBondContact O-CZ3 3.36Å; E341-W356 WeakPolarHBondContact OE2-CB 3.13Å; E341-W356 VanDerWaalsContact OE2-CG 3.25Å; E341-Q357 CarbonylContact C-O 3.46Å; E341-Q357 VanDerWaalsContact CA-O 3.27Å; E341-Q357 WeakPolarHBondContact CA-O 3.41Å; E341-V378 HydrophobicContact CG-CG2 4.01Å; E341-Y444 WeakPolarHBondContact CG-OH 3.49Å; E341-Y444 WeakPolarHBondContact OE1-CE2 3.48Å; E341-Y444 PolarHBondContact OE1-OH 2.82Å
342C98.9Very high95.4Very high0 Ų031.6 Ų31.60%018%0.18CC..EExtended strand (participates in β ladder)trans-111.8132.2174.3-61.90000110I294 P295 T296 M344 Q357 L359I294-C342 HydrophobicContact CG2-CB 3.97Å; P295-C342 WeakPolarHBondContact O-CA 3.32Å; T296-C342 PolarHBondContact OG1-SG 2.9Å; C342-M344 HydrophobicContact CB-CE 3.39Å; C342-Q357 PolarHBondContact N-O 3.23Å; C342-Q357 PolarHBondContact O-N 2.67Å; C342-L359 HydrophobicContact CB-CD1 3.66Å; C342-L359 VanDerWaalsContact SG-CD1 3.5Å
343W98.9Very high96.3Very high62 Ų6232.4 Ų32.424%0.23518%0.182CC..EExtended strand (participates in β ladder)trans-85118.5-179.8-177.8-91.9000111Y150 L151 P295 W356Y150-W343 PolarHBondContact O-NE1 2.86Å; L151-W343 HydrophobicContact CD1-CD2 3.53Å; L151-W343 VanDerWaalsContact CD1-CE2 3.4Å; L151-W343 HydrophobicContact CD1-CE3 4.04Å; L151-W343 HydrophobicContact CD1-CG 3.84Å; L151-W343 HydrophobicContact CD1-CH2 4.26Å; L151-W343 HydrophobicContact CD1-CZ2 3.8Å; L151-W343 HydrophobicContact CD1-CZ3 4.37Å; P295-W343 HydrophobicContact CB-CB 3.99Å; P295-W343 HydrophobicContact CG-CB 4.3Å; P295-W343 PolarHBondContact O-N 3.38Å; W343-W356 HydrophobicContact CB-CD2 4.49Å; W343-W356 HydrophobicContact CB-CE3 3.89Å; W343-W356 HydrophobicContact CB-CH2 4.07Å; W343-W356 HydrophobicContact CB-CZ3 3.68Å; W343-W356 AromaticContact CE3-CD1 3.92Å; W343-W356 AromaticContact CE3-CD2 3.76Å; W343-W356 HydrophobicContact CE3-CD2 3.76Å; W343-W356 AromaticContact CE3-CE2 3.66Å; W343-W356 HydrophobicContact CE3-CE3 4.31Å; W343-W356 AromaticContact CE3-CG 3.93Å; W343-W356 HydrophobicContact CE3-CG 3.93Å; W343-W356 HydrophobicContact CE3-CZ2 4.16Å; W343-W356 AromaticContact CE3-NE1 3.73Å; W343-W356 AromaticContact CZ3-CD1 3.91Å; W343-W356 HydrophobicContact CZ3-CD2 4.5Å; W343-W356 HydrophobicContact CZ3-CG 4.32Å; W343-W356 AromaticContact CZ3-NE1 3.81Å
344M98.8Very high97Very high1 Ų133.6 Ų33.61%0.00520%0.196CC..EExtended strand (participates in β ladder)trans-160.5158.4174.866.1-163.774.200113A148 V149 P218 V219 S222 I294 C342 G354 G355 Q357A148-M344 CarbonylContact O-C 3.5Å; A148-M344 VanDerWaalsContact O-CA 3.28Å; A148-M344 WeakPolarHBondContact O-CA 3.17Å; V149-M344 HydrophobicContact CG1-CB 4.35Å; P218-M344 HydrophobicContact CB-CB 4.23Å; P218-M344 HydrophobicContact CB-SD 4.18Å; P218-M344 HydrophobicContact CG-CB 4.03Å; P218-M344 HydrophobicContact CG-SD 4.43Å; V219-M344 HydrophobicContact CB-SD 4.48Å; V219-M344 HydrophobicContact CG2-SD 3.78Å; S222-M344 VanDerWaalsContact OG-CE 3.29Å; S222-M344 WeakPolarHBondContact OG-CE 3.36Å; I294-M344 HydrophobicContact CG2-CE 4.31Å; C342-M344 HydrophobicContact CB-CE 3.39Å; M344-G354 CarbonylContact O-C 3.51Å; M344-G354 WeakPolarHBondContact O-CA 3.43Å; M344-G355 PolarHBondContact N-O 3.1Å; M344-G355 PolarHBondContact O-N 2.75Å; M344-G355 VanDerWaalsContact O-O 3.14Å; M344-Q357 HydrophobicContact CE-CG 4.34Å; M344-Q357 HydrophobicContact CG-CG 3.59Å; M344-Q357 HydrophobicContact SD-CG 4.12Å
345A98.5Very high97.4Very high39 Ų3933.5 Ų33.532%0.32220%0.2SC..  trans-71.4148164.900000111.3A148A148-A345 HydrophobicContact CB-CB 4.32Å; A148-A345 PolarHBondContact O-N 3.32Å
346R98.1Very high97.9Very high12 Ų1235 Ų355%0.04521%0.206CC..  trans-119.276.6179-69.5-63.4-59.2-81.72.7111D348 L349 Q357 P375 N389R346-D348 WeakPolarHBondContact CA-OD1 3.4Å; R346-D348 IonicContact CZ-OD1 2.9Å; R346-D348 IonicContact CZ-OD2 3.38Å; R346-D348 IonicContact NE-OD1 2.66Å; R346-D348 PolarHBondContact NE-OD1 3.4Å; R346-D348 IonicContact NE-OD2 3.76Å; R346-D348 PolarHBondContact NE-OD2 3.38Å; R346-D348 IonicContact NH2-OD1 2.82Å; R346-D348 IonicContact NH2-OD2 2.93Å; R346-D348 PolarHBondContact NH2-OD2 2.84Å; R346-D348 PolarHBondContact O-N 3.19Å; R346-L349 HydrophobicContact CB-CB 4.02Å; R346-L349 HydrophobicContact CB-CD1 3.98Å; R346-L349 HydrophobicContact CB-CG 4Å; R346-L349 HydrophobicContact CG-CD1 4.17Å; R346-L349 PolarHBondContact O-N 3.47Å; R346-L349 VanDerWaalsContact O-N 3.11Å; R346-Q357 HydrophobicContact CG-CG 4.39Å; R346-P375 PolarHBondContact NH1-O 3.27Å; R346-N389 PolarHBondContact NH2-O 3.23Å
347K96Very high98.1Very high172 Ų17235 Ų3575%0.74821%0.206SC*.THydrogen-bonded Turntrans-67.8-16179.7-64.2-177.2-178.7177.70112.8L349K347-L349 VanDerWaalsContact C-N 3.35Å
348D96.6Very high98.2Very high75 Ų7535 Ų3540%0.40121%0.206SC..THydrogen-bonded Turntrans-81.2-11.3173.861.2-54.2000113.5R346R346-D348 WeakPolarHBondContact CA-OD1 3.4Å; R346-D348 IonicContact CZ-OD1 2.9Å; R346-D348 IonicContact CZ-OD2 3.38Å; R346-D348 IonicContact NE-OD1 2.66Å; R346-D348 PolarHBondContact NE-OD1 3.4Å; R346-D348 IonicContact NE-OD2 3.76Å; R346-D348 PolarHBondContact NE-OD2 3.38Å; R346-D348 IonicContact NH2-OD1 2.82Å; R346-D348 IonicContact NH2-OD2 2.93Å; R346-D348 PolarHBondContact NH2-OD2 2.84Å; R346-D348 PolarHBondContact O-N 3.19Å
349L98.1Very high98.2Very high19 Ų1935 Ų3510%0.09921%0.206CC..SBendtrans-111.6165.7178.4-62.8-172000111.7R346 K347 Y353 L388R346-L349 HydrophobicContact CB-CB 4.02Å; R346-L349 HydrophobicContact CB-CD1 3.98Å; R346-L349 HydrophobicContact CB-CG 4Å; R346-L349 HydrophobicContact CG-CD1 4.17Å; R346-L349 PolarHBondContact O-N 3.47Å; R346-L349 VanDerWaalsContact O-N 3.11Å; K347-L349 VanDerWaalsContact C-N 3.35Å; L349-Y353 HydrophobicContact CD1-CG 4.44Å; L349-L388 HydrophobicContact CD2-CB 4.29Å; L349-L388 HydrophobicContact CD2-CD2 4.49Å
350P97.5Very high98.2Very high66 Ų6635 Ų3543%0.42921%0.206SC..  trans-54.1150.8168.1-25.334.9000112.2G352 Y353 L388P350-G352 PolarHBondContact O-N 2.86Å; P350-Y353 HydrophobicContact CB-CD2 4.16Å; P350-Y353 HydrophobicContact CB-CE2 4.14Å; P350-Y353 HydrophobicContact CG-CE2 4.47Å; P350-Y353 WeakPolarHBondContact O-CD2 3.39Å; P350-L388 HydrophobicContact CG-CD2 4.5Å
351P97.1Very high98.2Very high135 Ų13535.1 Ų35.188%0.87721%0.206SC*.THydrogen-bonded Turntrans-53.8137.2177.3-26.935.1000112.5
352G97.2Very high98.1Very high40 Ų4035.3 Ų35.341%0.41221%0.208SC..THydrogen-bonded Turntrans105.1-617700000115.9P350 R379P350-G352 PolarHBondContact O-N 2.86Å; G352-R379 WeakPolarHBondContact O-CD 3.19Å; G352-R379 PolarHBondContact O-NH1 2.99Å
353Y98.4Very high97.8Very high33 Ų3336.5 Ų36.513%0.12922%0.215CC..  trans-98.88.4178-66.7-70.7000114.9L349 P350 Q357 S377 R379 A380 E385 L388L349-Y353 HydrophobicContact CD1-CG 4.44Å; P350-Y353 HydrophobicContact CB-CD2 4.16Å; P350-Y353 HydrophobicContact CB-CE2 4.14Å; P350-Y353 HydrophobicContact CG-CE2 4.47Å; P350-Y353 WeakPolarHBondContact O-CD2 3.39Å; Y353-Q357 PolarHBondContact O-NE2 3.31Å; Y353-S377 VanDerWaalsContact O-CB 3.31Å; Y353-S377 WeakPolarHBondContact O-CB 3.37Å; Y353-S377 PolarHBondContact O-OG 3.2Å; Y353-R379 HydrophobicContact CD1-CB 4.2Å; Y353-R379 HydrophobicContact CD1-CG 4.27Å; Y353-R379 HydrophobicContact CE1-CG 4.24Å; Y353-A380 HydrophobicContact CD1-CB 3.88Å; Y353-A380 HydrophobicContact CE1-CB 3.98Å; Y353-E385 HydrophobicContact CE1-CG 4.33Å; Y353-E385 WeakPolarHBondContact OH-CG 3.33Å; Y353-L388 HydrophobicContact CD1-CD1 4.16Å; Y353-L388 HydrophobicContact CD2-CD1 3.86Å; Y353-L388 HydrophobicContact CE1-CD1 3.98Å; Y353-L388 HydrophobicContact CE2-CD1 3.68Å; Y353-L388 HydrophobicContact CG-CD1 4.12Å
354G98.2Very high97.2Very high34 Ų3434.6 Ų34.635%0.35121%0.209SC..  trans-69.2-175.1166.200000112.8M344M344-G354 CarbonylContact O-C 3.51Å; M344-G354 WeakPolarHBondContact O-CA 3.43Å
355G98.7Very high96.6Very high13 Ų1338.1 Ų38.113%0.13423%0.226CC..EExtended strand (participates in β ladder)trans93.4-139.2-175.600000111M344 Q357M344-G355 PolarHBondContact N-O 3.1Å; M344-G355 PolarHBondContact O-N 2.75Å; M344-G355 VanDerWaalsContact O-O 3.14Å; G355-Q357 PolarHBondContact O-N 2.78Å; G355-Q357 PolarHBondContact O-NE2 3.41Å
356W98.9Very high96.2Very high34 Ų3440.9 Ų40.913%0.12923%0.233CC..EExtended strand (participates in β ladder)trans-69.1128.2-179.4-67117.2000113Y160 R297 E341 W343 V378Y160-W356 HydrophobicContact CD1-CH2 4.4Å; Y160-W356 AromaticContact CD2-CH2 3.57Å; Y160-W356 HydrophobicContact CD2-CH2 3.57Å; Y160-W356 AromaticContact CD2-CZ2 3.76Å; Y160-W356 HydrophobicContact CD2-CZ2 3.76Å; Y160-W356 AromaticContact CE2-CH2 3.81Å; Y160-W356 HydrophobicContact CE2-CH2 3.81Å; Y160-W356 AromaticContact CE2-CZ2 3.52Å; Y160-W356 HydrophobicContact CE2-CZ2 3.52Å; Y160-W356 AromaticContact CG-CH2 3.9Å; Y160-W356 HydrophobicContact CG-CH2 3.9Å; Y160-W356 HydrophobicContact CG-CZ2 4.46Å; R297-W356 HydrophobicContact CG-CE3 4.49Å; R297-W356 HydrophobicContact CG-CH2 4.13Å; R297-W356 HydrophobicContact CG-CZ3 4.07Å; E341-W356 HydrophobicContact CB-CB 4.31Å; E341-W356 HydrophobicContact CB-CD2 4.17Å; E341-W356 HydrophobicContact CB-CE3 3.65Å; E341-W356 HydrophobicContact CB-CG 4.49Å; E341-W356 HydrophobicContact CB-CZ3 4.33Å; E341-W356 HydrophobicContact CG-CB 4.23Å; E341-W356 WeakPolarHBondContact O-CZ3 3.36Å; E341-W356 WeakPolarHBondContact OE2-CB 3.13Å; E341-W356 VanDerWaalsContact OE2-CG 3.25Å; W343-W356 HydrophobicContact CB-CD2 4.49Å; W343-W356 HydrophobicContact CB-CE3 3.89Å; W343-W356 HydrophobicContact CB-CH2 4.07Å; W343-W356 HydrophobicContact CB-CZ3 3.68Å; W343-W356 AromaticContact CE3-CD1 3.92Å; W343-W356 AromaticContact CE3-CD2 3.76Å; W343-W356 HydrophobicContact CE3-CD2 3.76Å; W343-W356 AromaticContact CE3-CE2 3.66Å; W343-W356 HydrophobicContact CE3-CE3 4.31Å; W343-W356 AromaticContact CE3-CG 3.93Å; W343-W356 HydrophobicContact CE3-CG 3.93Å; W343-W356 HydrophobicContact CE3-CZ2 4.16Å; W343-W356 AromaticContact CE3-NE1 3.73Å; W343-W356 AromaticContact CZ3-CD1 3.91Å; W343-W356 HydrophobicContact CZ3-CD2 4.5Å; W343-W356 HydrophobicContact CZ3-CG 4.32Å; W343-W356 AromaticContact CZ3-NE1 3.81Å; W356-V378 HydrophobicContact CB-CB 4.36Å; W356-V378 HydrophobicContact CB-CG2 3.87Å; W356-V378 WeakPolarHBondContact O-CG2 3.3Å; W356-V378 PolarHBondContact O-N 3.34Å
357Q98.9Very high95.7Very high0 Ų040.7 Ų40.70%023%0.233CC..EExtended strand (participates in β ladder)trans-120125.1177.2-44-60.8-59.200110.1E341 C342 M344 R346 Y353 G355 L359 P375 A376 S377E341-Q357 CarbonylContact C-O 3.46Å; E341-Q357 VanDerWaalsContact CA-O 3.27Å; E341-Q357 WeakPolarHBondContact CA-O 3.41Å; C342-Q357 PolarHBondContact N-O 3.23Å; C342-Q357 PolarHBondContact O-N 2.67Å; M344-Q357 HydrophobicContact CE-CG 4.34Å; M344-Q357 HydrophobicContact CG-CG 3.59Å; M344-Q357 HydrophobicContact SD-CG 4.12Å; R346-Q357 HydrophobicContact CG-CG 4.39Å; Y353-Q357 PolarHBondContact O-NE2 3.31Å; G355-Q357 PolarHBondContact O-N 2.78Å; G355-Q357 PolarHBondContact O-NE2 3.41Å; Q357-L359 PolarHBondContact O-N 3.08Å; Q357-P375 HydrophobicContact CB-CB 3.6Å; Q357-P375 HydrophobicContact CG-CB 4.18Å; Q357-A376 CarbonylContact C-O 3.57Å; Q357-A376 VanDerWaalsContact CA-O 3.26Å; Q357-A376 WeakPolarHBondContact CA-O 3.44Å; Q357-S377 VanDerWaalsContact OE1-CA 3.24Å
358V98.9Very high95.2Very high0 Ų039.4 Ų39.40%024%0.235CC..EExtended strand (participates in β ladder)trans-67.8126.8173.2-179.60000109.5W339 N340 G374 P375 A376 V378 V395 Y444W339-V358 HydrophobicContact CD2-CG1 4.39Å; W339-V358 HydrophobicContact CG-CG1 4.06Å; N340-V358 CarbonylContact O-C 3.57Å; N340-V358 WeakPolarHBondContact O-CA 3.34Å; V358-G374 WeakPolarHBondContact O-CA 3.29Å; V358-P375 CarbonylContact O-C 3.59Å; V358-P375 VanDerWaalsContact O-CA 3.27Å; V358-P375 WeakPolarHBondContact O-CA 3.42Å; V358-A376 HydrophobicContact CB-CB 4.19Å; V358-A376 PolarHBondContact N-O 3.23Å; V358-A376 PolarHBondContact O-N 3.25Å; V358-V378 HydrophobicContact CG2-CG2 3.71Å; V358-V395 HydrophobicContact CB-CG1 4.05Å; V358-V395 HydrophobicContact CB-CG2 4.47Å; V358-V395 HydrophobicContact CG1-CG1 3.85Å; V358-V395 HydrophobicContact CG1-CG2 4.01Å; V358-V395 HydrophobicContact CG2-CG1 3.91Å; V358-Y444 HydrophobicContact CG2-CE1 3.73Å; V358-Y444 WeakPolarHBondContact CG2-OH 3.17Å
359L98.7Very high94.8Very high0 Ų038.4 Ų38.40%024%0.242CC..EExtended strand (participates in β ladder)trans-129137.1162.8-68.8113.8000109.7S222 C226 M285 N340 C342 Q357 C373 P375S222-L359 WeakPolarHBondContact O-CD2 3.37Å; C226-L359 HydrophobicContact CB-CD2 4.01Å; M285-L359 HydrophobicContact CE-CB 3.37Å; M285-L359 HydrophobicContact CE-CD1 4.37Å; M285-L359 HydrophobicContact CE-CD2 3.76Å; M285-L359 HydrophobicContact CE-CG 4.02Å; M285-L359 HydrophobicContact SD-CB 4.24Å; N340-L359 PolarHBondContact N-O 3.38Å; N340-L359 PolarHBondContact O-N 3.39Å; C342-L359 HydrophobicContact CB-CD1 3.66Å; C342-L359 VanDerWaalsContact SG-CD1 3.5Å; Q357-L359 PolarHBondContact O-N 3.08Å; L359-C373 WeakPolarHBondContact CA-O 3.42Å; L359-P375 HydrophobicContact CD1-CB 4.18Å; L359-P375 HydrophobicContact CD2-CB 4.41Å; L359-P375 HydrophobicContact CG-CB 4.17Å
360D98.6Very high94.4Very high1 Ų139.3 Ų39.31%0.00525%0.248CC..EExtended strand (participates in β ladder)trans-130.2108.4-179.4-177.28.8000110.5C226 H337 W339 T362 C373C226-D360 PolarHBondContact SG-O 2.86Å; H337-D360 IonicContact CD2-OD2 3.36Å; H337-D360 IonicContact CE1-OD1 3.88Å; H337-D360 IonicContact CE1-OD2 2.82Å; H337-D360 PolarHBondContact CE1-OD2 2.96Å; H337-D360 IonicContact NE2-OD1 2.92Å; H337-D360 IonicContact NE2-OD2 2.72Å; H337-D360 PolarHBondContact NE2-OD2 3.49Å; W339-D360 HydrophobicContact CB-CB 3.86Å; D360-T362 PolarHBondContact O-N 3.04Å; D360-T362 WeakPolarHBondContact OD1-CB 3.18Å; D360-T362 PolarHBondContact OD1-N 3.35Å; D360-T362 PolarHBondContact OD1-OG1 2.92Å; D360-C373 HydrophobicContact CB-CB 3.98Å; D360-C373 PolarHBondContact N-O 3.16Å; D360-C373 WeakPolarHBondContact O-CB 3.22Å; D360-C373 PolarHBondContact O-N 2.9Å
361A98.1Very high94.2Very high1 Ų139.1 Ų39.11%0.00824%0.239CC..  trans-78.5-5.617800000113.2I229 N230 F281 M285I229-A361 HydrophobicContact CB-CB 3.77Å; I229-A361 HydrophobicContact CG1-CB 4.25Å; I229-A361 HydrophobicContact CG2-CB 4.01Å; N230-A361 WeakPolarHBondContact CB-O 3.45Å; N230-A361 PolarHBondContact ND2-O 3.45Å; F281-A361 HydrophobicContact CB-CB 4.1Å; M285-A361 HydrophobicContact SD-CB 3.76Å
362T97.1Very high94Very high5 Ų533 Ų333%0.03120%0.199CC..SBendtrans-71.4126.9176-470000108.8W242 C278 F281 W334 H337 D360 Q364W242-T362 HydrophobicContact CH2-CG2 3.93Å; W242-T362 HydrophobicContact CZ2-CG2 3.85Å; C278-T362 WeakPolarHBondContact CA-OG1 3.41Å; C278-T362 HydrophobicContact CB-CG2 4.11Å; C278-T362 WeakPolarHBondContact CB-OG1 3.27Å; F281-T362 HydrophobicContact CD2-CG2 4.4Å; W334-T362 HydrophobicContact CH2-CG2 4.41Å; H337-T362 PolarHBondContact CE1-OG1 2.79Å; D360-T362 PolarHBondContact O-N 3.04Å; D360-T362 WeakPolarHBondContact OD1-CB 3.18Å; D360-T362 PolarHBondContact OD1-N 3.35Å; D360-T362 PolarHBondContact OD1-OG1 2.92Å; T362-Q364 VanDerWaalsContact C-N 3.28Å; T362-Q364 HydrophobicContact CG2-CG 4.18Å; T362-Q364 PolarHBondContact O-N 3.15Å
363P92.8Very high93.9Very high25 Ų2531.4 Ų31.416%0.16218%0.182CC..SBendtrans-77.976.7-175.232.9-37.6000111.5N230 N232 Y371N230-P363 HydrophobicContact CB-CB 4.44Å; N230-P363 HydrophobicContact CB-CG 4.31Å; N232-P363 WeakPolarHBondContact ND2-CB 3.33Å; N232-P363 VanDerWaalsContact ND2-CG 3.27Å; N232-P363 WeakPolarHBondContact ND2-CG 3.36Å; P363-Y371 HydrophobicContact CB-CD1 3.67Å; P363-Y371 HydrophobicContact CB-CE1 4.27Å; P363-Y371 HydrophobicContact CB-CG 3.84Å
364Q86.8Confident93.9Very high22 Ų2229.8 Ų29.810%0.10318%0.176CC..SBendtrans-95.7-61176.3-71.8-179.5-35.700110.8W334 H337 T362 F394W334-Q364 HydrophobicContact CZ2-CG 4.49Å; H337-Q364 PolarHBondContact NE2-OE1 3.27Å; T362-Q364 VanDerWaalsContact C-N 3.28Å; T362-Q364 HydrophobicContact CG2-CG 4.18Å; T362-Q364 PolarHBondContact O-N 3.15Å; Q364-F394 HydrophobicContact CB-CE1 4.38Å; Q364-F394 HydrophobicContact CB-CZ 3.75Å; Q364-F394 VanDerWaalsContact OE1-CZ 3.29Å
365E86.1Confident93.9Very high75 Ų7528.2 Ų28.235%0.3516%0.159SC..SBendtrans-120.6148.2-178.4-74.3-62150.200112F394E365-F394 HydrophobicContact CB-CD2 4.19Å; E365-F394 HydrophobicContact CB-CE2 4.14Å; E365-F394 HydrophobicContact CB-CG 4.43Å; E365-F394 HydrophobicContact CB-CZ 4.38Å; E365-F394 HydrophobicContact CG-CD2 3.49Å; E365-F394 VanDerWaalsContact CG-CD2 3.49Å; E365-F394 HydrophobicContact CG-CE2 3.3Å; E365-F394 HydrophobicContact CG-CG 4.2Å; E365-F394 HydrophobicContact CG-CZ 3.92Å
366M88.7Confident93.9Very high96 Ų9627.6 Ų27.647%0.47315%0.153SC..  trans-87.1130.2175.2-71.3-176.1172.100110.8V370 Y371M366-V370 CarbonylContact C-O 3.58Å; M366-V370 WeakPolarHBondContact CA-O 3.37Å; M366-Y371 HydrophobicContact CE-CD2 3.75Å; M366-Y371 HydrophobicContact CE-CE1 4.49Å; M366-Y371 HydrophobicContact CE-CE2 3.17Å; M366-Y371 HydrophobicContact CG-CD1 4.04Å; M366-Y371 HydrophobicContact CG-CD2 4.19Å; M366-Y371 HydrophobicContact CG-CE1 3.94Å; M366-Y371 HydrophobicContact CG-CE2 4.12Å; M366-Y371 HydrophobicContact CG-CG 4.17Å; M366-Y371 HydrophobicContact SD-CE2 4.5Å
367S88.8Confident93.9Very high8 Ų826 Ų266%0.05615%0.147CC..BIsolated β-bridgetrans-107.2117.7168.8-172.20000109R223 G369 V370 C372 D391R223-S367 PolarHBondContact NH2-OG 3.36Å; S367-G369 PolarHBondContact O-N 3.02Å; S367-V370 PolarHBondContact N-O 3.43Å; S367-V370 PolarHBondContact O-N 3.15Å; S367-C372 WeakPolarHBondContact CB-O 3.4Å; S367-D391 WeakPolarHBondContact CB-OD1 3.21Å; S367-D391 VanDerWaalsContact OG-CG 3.28Å; S367-D391 PolarHBondContact OG-OD1 3.45Å; S367-D391 PolarHBondContact OG-OD2 3.03Å
368N86.1Confident93.9Very high146 Ų14626.4 Ų26.478%0.78115%0.149SC*.THydrogen-bonded Turntrans53.836.3-175.6-58.7-33.7000113.7
369G86.5Confident93.9Very high54 Ų5432.8 Ų32.856%0.55717%0.174SC*.THydrogen-bonded Turntrans81.110.117700000115.5S367S367-G369 PolarHBondContact O-N 3.02Å
370V90.7Very high93.9Very high37 Ų3732.8 Ų32.822%0.22417%0.174CC..BIsolated β-bridgetrans-127.2142.1176.3179.90000109.2A227 D233 M366 S367 C372A227-V370 HydrophobicContact CB-CG1 3.92Å; D233-V370 HydrophobicContact CB-CG1 4.3Å; M366-V370 CarbonylContact C-O 3.58Å; M366-V370 WeakPolarHBondContact CA-O 3.37Å; S367-V370 PolarHBondContact N-O 3.43Å; S367-V370 PolarHBondContact O-N 3.15Å; V370-C372 VanDerWaalsContact C-N 3.26Å; V370-C372 HydrophobicContact CG1-CB 4.39Å; V370-C372 PolarHBondContact O-N 3.1Å
371Y92.8Very high93.9Very high63 Ų6332.8 Ų32.825%0.24717%0.173CC..SBendtrans-70.180.9173-76.8-74.1000111.4N230 N232 D233 P363 M366N230-Y371 PolarHBondContact ND2-O 3.04Å; N232-Y371 HydrophobicContact CB-CD2 3.41Å; N232-Y371 VanDerWaalsContact CB-CD2 3.41Å; N232-Y371 HydrophobicContact CB-CE2 3.91Å; N232-Y371 HydrophobicContact CB-CG 4.17Å; D233-Y371 WeakPolarHBondContact OD2-CB 3.43Å; D233-Y371 WeakPolarHBondContact OD2-CD2 3.46Å; D233-Y371 PolarHBondContact OD2-N 3.14Å; P363-Y371 HydrophobicContact CB-CD1 3.67Å; P363-Y371 HydrophobicContact CB-CE1 4.27Å; P363-Y371 HydrophobicContact CB-CG 3.84Å; M366-Y371 HydrophobicContact CE-CD2 3.75Å; M366-Y371 HydrophobicContact CE-CE1 4.49Å; M366-Y371 HydrophobicContact CE-CE2 3.17Å; M366-Y371 HydrophobicContact CG-CD1 4.04Å; M366-Y371 HydrophobicContact CG-CD2 4.19Å; M366-Y371 HydrophobicContact CG-CE1 3.94Å; M366-Y371 HydrophobicContact CG-CE2 4.12Å; M366-Y371 HydrophobicContact CG-CG 4.17Å; M366-Y371 HydrophobicContact SD-CE2 4.5Å
372C92.3Very high93.9Very high5 Ų535.2 Ų35.23%0.03418%0.184CC..  trans-147.5121179.3167.30000108.7R223 A227 S367 V370R223-C372 PolarHBondContact O-SG 3.31Å; A227-C372 HydrophobicContact CB-CB 4.05Å; S367-C372 WeakPolarHBondContact CB-O 3.4Å; V370-C372 VanDerWaalsContact C-N 3.26Å; V370-C372 HydrophobicContact CG1-CB 4.39Å; V370-C372 PolarHBondContact O-N 3.1Å
373C96.8Very high93.9Very high7 Ų737.3 Ų37.35%0.04719%0.193CC..EExtended strand (participates in β ladder)trans-112.4134.1175.1-176.80000111.3C226 L359 D360C226-C373 PolarHBondContact SG-O 3.23Å; C226-C373 VanDerWaalsContact SG-O 3.35Å; L359-C373 WeakPolarHBondContact CA-O 3.42Å; D360-C373 HydrophobicContact CB-CB 3.98Å; D360-C373 PolarHBondContact N-O 3.16Å; D360-C373 WeakPolarHBondContact O-CB 3.22Å; D360-C373 PolarHBondContact O-N 2.9Å
374G96.9Very high94.2Very high0 Ų036.1 Ų36.10%019%0.185CC..EExtended strand (participates in β ladder)trans89.6179.9178.300000113.9R223 V358 D391R223-G374 VanDerWaalsContact CG-O 3.3Å; R223-G374 WeakPolarHBondContact CG-O 3.36Å; R223-G374 PolarHBondContact NH1-O 2.98Å; V358-G374 WeakPolarHBondContact O-CA 3.29Å; G374-D391 PolarHBondContact N-OD2 3.41Å
375P98.3Very high94.7Very high0 Ų036.7 Ų36.70%019%0.188CC..EExtended strand (participates in β ladder)cis-74.5118.16.726.3-31.6000113.3V219 R346 Q357 V358 L359 Y390V219-P375 HydrophobicContact CB-CG 4.42Å; V219-P375 HydrophobicContact CG1-CG 3.8Å; V219-P375 HydrophobicContact CG2-CG 4.49Å; R346-P375 PolarHBondContact NH1-O 3.27Å; Q357-P375 HydrophobicContact CB-CB 3.6Å; Q357-P375 HydrophobicContact CG-CB 4.18Å; V358-P375 CarbonylContact O-C 3.59Å; V358-P375 VanDerWaalsContact O-CA 3.27Å; V358-P375 WeakPolarHBondContact O-CA 3.42Å; L359-P375 HydrophobicContact CD1-CB 4.18Å; L359-P375 HydrophobicContact CD2-CB 4.41Å; L359-P375 HydrophobicContact CG-CB 4.17Å; P375-Y390 HydrophobicContact CG-CD2 4.01Å; P375-Y390 HydrophobicContact CG-CE2 4.44Å; P375-Y390 PolarHBondContact O-N 2.98Å; P375-Y390 VanDerWaalsContact O-N 3.16Å
376A98.6Very high95.2Very high0 Ų033.4 Ų33.40%017%0.173CC..EExtended strand (participates in β ladder)trans-98.8126.3172.800000109.6Q357 V358 V378 I381 Y390 T392 V395Q357-A376 CarbonylContact C-O 3.57Å; Q357-A376 VanDerWaalsContact CA-O 3.26Å; Q357-A376 WeakPolarHBondContact CA-O 3.44Å; V358-A376 HydrophobicContact CB-CB 4.19Å; V358-A376 PolarHBondContact N-O 3.23Å; V358-A376 PolarHBondContact O-N 3.25Å; A376-V378 PolarHBondContact O-N 3.29Å; A376-I381 HydrophobicContact CB-CD1 4.32Å; A376-Y390 WeakPolarHBondContact CA-O 3.45Å; A376-Y390 WeakPolarHBondContact CB-O 3.5Å; A376-T392 HydrophobicContact CB-CG2 4.02Å; A376-V395 HydrophobicContact CB-CB 4.29Å; A376-V395 HydrophobicContact CB-CG2 3.89Å
377S98.8Very high95.5Very high0 Ų033.7 Ų33.70%018%0.177CC..EExtended strand (participates in β ladder)trans-64.8123.4179177.90000110.5Y353 Q357 R379 A380 I381Y353-S377 VanDerWaalsContact O-CB 3.31Å; Y353-S377 WeakPolarHBondContact O-CB 3.37Å; Y353-S377 PolarHBondContact O-OG 3.2Å; Q357-S377 VanDerWaalsContact OE1-CA 3.24Å; S377-R379 PolarHBondContact O-N 3.45Å; S377-A380 WeakPolarHBondContact O-CA 3.37Å; S377-A380 VanDerWaalsContact O-CB 3.32Å; S377-A380 WeakPolarHBondContact O-CB 3.23Å; S377-A380 PolarHBondContact O-N 3.11Å; S377-I381 WeakPolarHBondContact O-CG1 3.45Å; S377-I381 PolarHBondContact O-N 3.07Å; S377-I381 VanDerWaalsContact O-N 3.09Å
378V98.9Very high95.9Very high10 Ų1034.7 Ų34.76%0.06118%0.181CC..Hα-helixtrans-56.4-35.7177.6172.30000110.7E341 W356 V358 A376 I381 K382 N443 Y444E341-V378 HydrophobicContact CG-CG2 4.01Å; W356-V378 HydrophobicContact CB-CB 4.36Å; W356-V378 HydrophobicContact CB-CG2 3.87Å; W356-V378 WeakPolarHBondContact O-CG2 3.3Å; W356-V378 PolarHBondContact O-N 3.34Å; V358-V378 HydrophobicContact CG2-CG2 3.71Å; A376-V378 PolarHBondContact O-N 3.29Å; V378-I381 WeakPolarHBondContact O-CB 3.24Å; V378-I381 PolarHBondContact O-N 3.05Å; V378-K382 PolarHBondContact O-N 3.31Å; V378-N443 HydrophobicContact CG1-CB 4.13Å; V378-N443 VanDerWaalsContact CG1-O 3.28Å; V378-N443 WeakPolarHBondContact CG1-O 3.39Å; V378-Y444 HydrophobicContact CG1-CD2 4.15Å; V378-Y444 HydrophobicContact CG1-CE1 4.47Å; V378-Y444 HydrophobicContact CG1-CE2 4.04Å; V378-Y444 HydrophobicContact CG1-CG 4.39Å; V378-Y444 HydrophobicContact CG2-CE1 4.38Å; V378-Y444 HydrophobicContact CG2-CE2 4.47Å
379R98.7Very high96.4Very high134 Ų13432.2 Ų32.251%0.50617%0.168SC..Hα-helixtrans-63.6-42173-173.6-176.4-176.4164.52.4112.5G352 Y353 S377 I381 K382 E383G352-R379 WeakPolarHBondContact O-CD 3.19Å; G352-R379 PolarHBondContact O-NH1 2.99Å; Y353-R379 HydrophobicContact CD1-CB 4.2Å; Y353-R379 HydrophobicContact CD1-CG 4.27Å; Y353-R379 HydrophobicContact CE1-CG 4.24Å; S377-R379 PolarHBondContact O-N 3.45Å; R379-I381 PolarHBondContact O-N 3.42Å; R379-K382 PolarHBondContact O-N 2.85Å; R379-E383 HydrophobicContact CG-CG 4.27Å; R379-E383 WeakPolarHBondContact O-CG 3.34Å; R379-E383 PolarHBondContact O-N 2.84Å
380A98.7Very high96.9Very high0 Ų032 Ų320%015%0.151CC..Hα-helixtrans-61.2-36.9176.300000111.3Y353 S377 E383 G384 E385 L388 T392Y353-A380 HydrophobicContact CD1-CB 3.88Å; Y353-A380 HydrophobicContact CE1-CB 3.98Å; S377-A380 WeakPolarHBondContact O-CA 3.37Å; S377-A380 VanDerWaalsContact O-CB 3.32Å; S377-A380 WeakPolarHBondContact O-CB 3.23Å; S377-A380 PolarHBondContact O-N 3.11Å; A380-E383 PolarHBondContact O-N 3.13Å; A380-G384 PolarHBondContact O-N 3.45Å; A380-G384 VanDerWaalsContact O-N 3.09Å; A380-E385 HydrophobicContact CB-CB 4Å; A380-E385 PolarHBondContact O-N 3.13Å; A380-L388 HydrophobicContact CB-CD1 4.11Å; A380-T392 HydrophobicContact CB-CG2 4.22Å
381I98.7Very high97.2Very high0 Ų031.9 Ų31.90%015%0.149CC..Hα-helixtrans-63.2-50.9173.7-53.3-51.7000110.6A376 S377 V378 R379 E383 G384 T392 V395 F396 V399 Y444A376-I381 HydrophobicContact CB-CD1 4.32Å; S377-I381 WeakPolarHBondContact O-CG1 3.45Å; S377-I381 PolarHBondContact O-N 3.07Å; S377-I381 VanDerWaalsContact O-N 3.09Å; V378-I381 WeakPolarHBondContact O-CB 3.24Å; V378-I381 PolarHBondContact O-N 3.05Å; R379-I381 PolarHBondContact O-N 3.42Å; I381-E383 VanDerWaalsContact C-N 3.25Å; I381-E383 PolarHBondContact O-N 2.89Å; I381-G384 PolarHBondContact O-N 2.97Å; I381-G384 VanDerWaalsContact O-N 3.13Å; I381-T392 HydrophobicContact CD1-CG2 4.04Å; I381-V395 HydrophobicContact CD1-CB 3.68Å; I381-V395 HydrophobicContact CD1-CG1 3.65Å; I381-V395 HydrophobicContact CG1-CB 4.29Å; I381-V395 HydrophobicContact CG1-CG1 3.68Å; I381-F396 HydrophobicContact CD1-CB 4.47Å; I381-F396 HydrophobicContact CG2-CB 4.49Å; I381-F396 HydrophobicContact CG2-CD2 4.15Å; I381-F396 WeakPolarHBondContact O-CD2 3.33Å; I381-F396 WeakPolarHBondContact O-CE2 3.31Å; I381-V399 HydrophobicContact CG2-CG2 3.76Å; I381-Y444 HydrophobicContact CG2-CD1 4.19Å
382K98.6Very high97.4Very high53 Ų5329 Ų2923%0.2314%0.137CC..Hα-helixtrans-57.7-36.2178-175.5170.9178.2166.90114.1V378 R379 E442 N443 Y444 Y446 V456V378-K382 PolarHBondContact O-N 3.31Å; R379-K382 PolarHBondContact O-N 2.85Å; K382-E442 VanDerWaalsContact CE-O 3.31Å; K382-E442 WeakPolarHBondContact CE-O 3.27Å; K382-E442 PolarHBondContact NZ-O 3.35Å; K382-N443 WeakPolarHBondContact CB-O 3.46Å; K382-Y444 WeakPolarHBondContact CA-O 3.45Å; K382-Y444 PolarHBondContact N-O 3.42Å; K382-Y446 HydrophobicContact CG-CD2 4.43Å; K382-Y446 HydrophobicContact CG-CE2 4.06Å; K382-Y446 WeakPolarHBondContact O-CE2 3.41Å; K382-V456 WeakPolarHBondContact O-CG1 3.28Å
383E98.4Very high97.5Very high48 Ų4831.2 Ų31.222%0.22415%0.152CC..THydrogen-bonded Turntrans-92.82.6-178.2-57.8-5515700113.9R379 A380 I381 E385 Y446 K459R379-E383 HydrophobicContact CG-CG 4.27Å; R379-E383 WeakPolarHBondContact O-CG 3.34Å; R379-E383 PolarHBondContact O-N 2.84Å; A380-E383 PolarHBondContact O-N 3.13Å; I381-E383 VanDerWaalsContact C-N 3.25Å; I381-E383 PolarHBondContact O-N 2.89Å; E383-E385 VanDerWaalsContact C-N 3.33Å; E383-E385 HydrophobicContact CB-CG 3.95Å; E383-E385 PolarHBondContact O-N 3.3Å; E383-Y446 VanDerWaalsContact CD-OH 3.29Å; E383-Y446 PolarHBondContact OE1-OH 3.28Å; E383-Y446 PolarHBondContact OE2-OH 3.15Å; E383-K459 WeakPolarHBondContact O-CE 3.43Å; E383-K459 PolarHBondContact O-NZ 3.39Å
384G97.8Very high97.4Very high0 Ų031.8 Ų31.80%015%0.154CC..THydrogen-bonded Turntrans66.431.2179.800000114A380 I381 V386A380-G384 PolarHBondContact O-N 3.45Å; A380-G384 VanDerWaalsContact O-N 3.09Å; I381-G384 PolarHBondContact O-N 2.97Å; I381-G384 VanDerWaalsContact O-N 3.13Å; G384-V386 VanDerWaalsContact C-N 3.26Å; G384-V386 PolarHBondContact O-N 2.83Å; G384-V386 VanDerWaalsContact O-N 3.14Å
385E97.8Very high97.4Very high35 Ų3531.8 Ų31.816%0.16415%0.154CC..  trans-87.562.7179.3-57.8-71.1-178.300111Y353 A380 E383 D387 L388 T392 K459 K463Y353-E385 HydrophobicContact CE1-CG 4.33Å; Y353-E385 WeakPolarHBondContact OH-CG 3.33Å; A380-E385 HydrophobicContact CB-CB 4Å; A380-E385 PolarHBondContact O-N 3.13Å; E383-E385 VanDerWaalsContact C-N 3.33Å; E383-E385 HydrophobicContact CB-CG 3.95Å; E383-E385 PolarHBondContact O-N 3.3Å; E385-D387 PolarHBondContact O-N 3.41Å; E385-L388 HydrophobicContact CB-CD1 3.84Å; E385-L388 HydrophobicContact CB-CG 4.13Å; E385-L388 PolarHBondContact O-N 2.74Å; E385-T392 PolarHBondContact O-OG1 2.89Å; E385-K459 WeakPolarHBondContact OE1-CE 3.19Å; E385-K459 IonicContact OE1-NZ 3.69Å; E385-K459 PolarHBondContact OE1-NZ 2.95Å; E385-K459 IonicContact OE2-NZ 3.51Å; E385-K463 IonicContact OE2-NZ 2.67Å; E385-K463 PolarHBondContact OE2-NZ 3.23Å
386V96.6Very high97.4Very high6 Ų631.8 Ų31.84%0.03615%0.154CC..THydrogen-bonded Turntrans-74.92.7-173.1-62.20000115G384 T392 P393 F396 A460 K463 L464G384-V386 VanDerWaalsContact C-N 3.26Å; G384-V386 PolarHBondContact O-N 2.83Å; G384-V386 VanDerWaalsContact O-N 3.14Å; V386-T392 VanDerWaalsContact CA-OG1 3.26Å; V386-T392 WeakPolarHBondContact CA-OG1 2.92Å; V386-T392 PolarHBondContact O-OG1 3.18Å; V386-T392 VanDerWaalsContact O-OG1 3.13Å; V386-P393 HydrophobicContact CB-CG 4.27Å; V386-P393 WeakPolarHBondContact O-CD 3.29Å; V386-P393 WeakPolarHBondContact O-CG 3.2Å; V386-F396 HydrophobicContact CG1-CB 3.71Å; V386-F396 HydrophobicContact CG1-CD1 4.25Å; V386-F396 HydrophobicContact CG1-CD2 4.07Å; V386-F396 HydrophobicContact CG1-CG 3.74Å; V386-A460 HydrophobicContact CG1-CB 3.83Å; V386-A460 HydrophobicContact CG2-CB 4.22Å; V386-K463 HydrophobicContact CG2-CB 3.67Å; V386-K463 HydrophobicContact CG2-CD 4.26Å; V386-L464 HydrophobicContact CB-CD2 4.26Å; V386-L464 HydrophobicContact CG2-CD2 3.91Å; V386-L464 HydrophobicContact CG2-CG 3.98Å
387D95.6Very high97.2Very high102 Ų10232 Ų3255%0.54516%0.155SC..THydrogen-bonded Turntrans-100.2-8175.255.9-37.5000112.7E385 K463E385-D387 PolarHBondContact O-N 3.41Å; D387-K463 VanDerWaalsContact CG-NZ 3.29Å; D387-K463 IonicContact OD1-NZ 2.67Å; D387-K463 PolarHBondContact OD1-NZ 2.98Å; D387-K463 IonicContact OD2-NZ 3.76Å; D387-K463 PolarHBondContact OD2-NZ 2.61Å
388L96.9Very high97Very high28 Ų2832 Ų3215%0.14716%0.155CC..SBendtrans-80.8142.1176.8-63.8-177.7000111L349 P350 Y353 A380 E385 T392L349-L388 HydrophobicContact CD2-CB 4.29Å; L349-L388 HydrophobicContact CD2-CD2 4.49Å; P350-L388 HydrophobicContact CG-CD2 4.5Å; Y353-L388 HydrophobicContact CD1-CD1 4.16Å; Y353-L388 HydrophobicContact CD2-CD1 3.86Å; Y353-L388 HydrophobicContact CE1-CD1 3.98Å; Y353-L388 HydrophobicContact CE2-CD1 3.68Å; Y353-L388 HydrophobicContact CG-CD1 4.12Å; A380-L388 HydrophobicContact CB-CD1 4.11Å; E385-L388 HydrophobicContact CB-CD1 3.84Å; E385-L388 HydrophobicContact CB-CG 4.13Å; E385-L388 PolarHBondContact O-N 2.74Å; L388-T392 HydrophobicContact CB-CG2 4.49Å; L388-T392 WeakPolarHBondContact O-CB 3.42Å; L388-T392 WeakPolarHBondContact O-CG2 3.33Å; L388-T392 PolarHBondContact O-OG1 3.25Å
389N96.3Very high96.9Very high94 Ų9431.5 Ų31.550%0.50315%0.152SC..THydrogen-bonded Turntrans-67145.6172.2-73.9-29000110.9R346R346-N389 PolarHBondContact NH2-O 3.23Å
390Y96.4Very high96.8Very high50 Ų5025.9 Ų25.920%0.19613%0.132CC..THydrogen-bonded Turncis-112.8147.1-3-65.9-92000109.3V219 P375 A376 T392V219-Y390 HydrophobicContact CG1-CE2 3.87Å; P375-Y390 HydrophobicContact CG-CD2 4.01Å; P375-Y390 HydrophobicContact CG-CE2 4.44Å; P375-Y390 PolarHBondContact O-N 2.98Å; P375-Y390 VanDerWaalsContact O-N 3.16Å; A376-Y390 WeakPolarHBondContact CA-O 3.45Å; A376-Y390 WeakPolarHBondContact CB-O 3.5Å; Y390-T392 PolarHBondContact O-N 3.27Å
391D96.5Very high96.6Very high35 Ų3526 Ų2619%0.18713%0.133CC..THydrogen-bonded Turntrans54.122.4165.4-43-52.2000115R223 S367 G374 F394 V395R223-D391 IonicContact NH1-OD2 3.69Å; R223-D391 PolarHBondContact NH1-OD2 2.73Å; S367-D391 WeakPolarHBondContact CB-OD1 3.21Å; S367-D391 VanDerWaalsContact OG-CG 3.28Å; S367-D391 PolarHBondContact OG-OD1 3.45Å; S367-D391 PolarHBondContact OG-OD2 3.03Å; G374-D391 PolarHBondContact N-OD2 3.41Å; D391-F394 PolarHBondContact O-N 3.49Å; D391-F394 VanDerWaalsContact O-N 3.13Å; D391-V395 PolarHBondContact O-N 3.14Å; D391-V395 VanDerWaalsContact O-N 3.11Å
392T96.9Very high96.3Very high1 Ų126.2 Ų26.21%0.00613%0.134CC..Hα-helixtrans-60.1-32.6-178.250.80000114.1A376 A380 I381 E385 V386 L388 Y390 F394 F396A376-T392 HydrophobicContact CB-CG2 4.02Å; A380-T392 HydrophobicContact CB-CG2 4.22Å; I381-T392 HydrophobicContact CD1-CG2 4.04Å; E385-T392 PolarHBondContact O-OG1 2.89Å; V386-T392 VanDerWaalsContact CA-OG1 3.26Å; V386-T392 WeakPolarHBondContact CA-OG1 2.92Å; V386-T392 PolarHBondContact O-OG1 3.18Å; V386-T392 VanDerWaalsContact O-OG1 3.13Å; L388-T392 HydrophobicContact CB-CG2 4.49Å; L388-T392 WeakPolarHBondContact O-CB 3.42Å; L388-T392 WeakPolarHBondContact O-CG2 3.33Å; L388-T392 PolarHBondContact O-OG1 3.25Å; Y390-T392 PolarHBondContact O-N 3.27Å; T392-F394 VanDerWaalsContact C-N 3.35Å; T392-F394 PolarHBondContact O-N 2.98Å; T392-F396 WeakPolarHBondContact O-CB 3.41Å; T392-F396 PolarHBondContact O-N 2.79Å
393P95.4Very high95.9Very high52 Ų5224 Ų2434%0.33813%0.125SC..Hα-helixtrans-55.7-47.8171.1-29.137.9000113.4V386 F396 S397 L464V386-P393 HydrophobicContact CB-CG 4.27Å; V386-P393 WeakPolarHBondContact O-CD 3.29Å; V386-P393 WeakPolarHBondContact O-CG 3.2Å; P393-F396 PolarHBondContact O-N 3.46Å; P393-S397 PolarHBondContact O-N 2.91Å; P393-S397 VanDerWaalsContact O-N 3.07Å; P393-L464 HydrophobicContact CB-CD2 3.69Å; P393-L464 HydrophobicContact CG-CD2 3.9Å
394F94.6Very high95.6Very high20 Ų2022.5 Ų22.59%0.08812%0.119CC..Hα-helixtrans-69.4-48.6-175.8179.5-107.1000110.5H306 Q364 E365 D391 T392 F396 S397 M398H306-F394 AromaticContact CD2-CE2 3.6Å; H306-F394 AromaticContact CD2-CZ 3.89Å; H306-F394 AromaticContact NE2-CE2 3.95Å; Q364-F394 HydrophobicContact CB-CE1 4.38Å; Q364-F394 HydrophobicContact CB-CZ 3.75Å; Q364-F394 VanDerWaalsContact OE1-CZ 3.29Å; E365-F394 HydrophobicContact CB-CD2 4.19Å; E365-F394 HydrophobicContact CB-CE2 4.14Å; E365-F394 HydrophobicContact CB-CG 4.43Å; E365-F394 HydrophobicContact CB-CZ 4.38Å; E365-F394 HydrophobicContact CG-CD2 3.49Å; E365-F394 VanDerWaalsContact CG-CD2 3.49Å; E365-F394 HydrophobicContact CG-CE2 3.3Å; E365-F394 HydrophobicContact CG-CG 4.2Å; E365-F394 HydrophobicContact CG-CZ 3.92Å; D391-F394 PolarHBondContact O-N 3.49Å; D391-F394 VanDerWaalsContact O-N 3.13Å; T392-F394 VanDerWaalsContact C-N 3.35Å; T392-F394 PolarHBondContact O-N 2.98Å; F394-F396 PolarHBondContact O-N 3.35Å; F394-S397 PolarHBondContact O-N 3.38Å; F394-S397 VanDerWaalsContact O-N 3.13Å; F394-S397 PolarHBondContact O-OG 3Å; F394-M398 HydrophobicContact CD1-CE 4.26Å; F394-M398 HydrophobicContact CD1-SD 4.45Å; F394-M398 HydrophobicContact CE1-CE 4.13Å; F394-M398 HydrophobicContact CE1-CG 4.27Å; F394-M398 HydrophobicContact CE1-SD 3.86Å; F394-M398 HydrophobicContact CZ-CG 4.44Å; F394-M398 HydrophobicContact CZ-SD 4.31Å; F394-M398 WeakPolarHBondContact O-CG 3.45Å; F394-M398 PolarHBondContact O-N 3.28Å; F394-M398 VanDerWaalsContact O-N 3.15Å
395V96.9Very high95.2Very high0 Ų022.9 Ų22.90%012%0.121CC..Hα-helixtrans-62.2-35.2178-179.90000111.6V358 A376 I381 D391 M398V358-V395 HydrophobicContact CB-CG1 4.05Å; V358-V395 HydrophobicContact CB-CG2 4.47Å; V358-V395 HydrophobicContact CG1-CG1 3.85Å; V358-V395 HydrophobicContact CG1-CG2 4.01Å; V358-V395 HydrophobicContact CG2-CG1 3.91Å; A376-V395 HydrophobicContact CB-CB 4.29Å; A376-V395 HydrophobicContact CB-CG2 3.89Å; I381-V395 HydrophobicContact CD1-CB 3.68Å; I381-V395 HydrophobicContact CD1-CG1 3.65Å; I381-V395 HydrophobicContact CG1-CB 4.29Å; I381-V395 HydrophobicContact CG1-CG1 3.68Å; D391-V395 PolarHBondContact O-N 3.14Å; D391-V395 VanDerWaalsContact O-N 3.11Å; V395-M398 HydrophobicContact CB-CE 4.09Å; V395-M398 HydrophobicContact CG1-CE 4.08Å; V395-M398 HydrophobicContact CG2-CE 3.92Å; V395-M398 PolarHBondContact O-N 3.39Å
396F97.6Very high94.9Very high0 Ų023.1 Ų23.10%012%0.12CC..Hα-helixtrans-65.9-41.1175.6-172-86.2000112.4L312 I381 V386 T392 P393 F394 M398 V399 N400 V456 F457 A460L312-F396 HydrophobicContact CD1-CD1 4.21Å; L312-F396 HydrophobicContact CD1-CE1 4.07Å; L312-F396 HydrophobicContact CD2-CD1 3.98Å; I381-F396 HydrophobicContact CD1-CB 4.47Å; I381-F396 HydrophobicContact CG2-CB 4.49Å; I381-F396 HydrophobicContact CG2-CD2 4.15Å; I381-F396 WeakPolarHBondContact O-CD2 3.33Å; I381-F396 WeakPolarHBondContact O-CE2 3.31Å; V386-F396 HydrophobicContact CG1-CB 3.71Å; V386-F396 HydrophobicContact CG1-CD1 4.25Å; V386-F396 HydrophobicContact CG1-CD2 4.07Å; V386-F396 HydrophobicContact CG1-CG 3.74Å; T392-F396 WeakPolarHBondContact O-CB 3.41Å; T392-F396 PolarHBondContact O-N 2.79Å; P393-F396 PolarHBondContact O-N 3.46Å; F394-F396 PolarHBondContact O-N 3.35Å; F396-M398 VanDerWaalsContact C-N 3.29Å; F396-M398 PolarHBondContact O-N 3.19Å; F396-V399 PolarHBondContact O-N 2.8Å; F396-N400 HydrophobicContact CD1-CB 3.99Å; F396-N400 WeakPolarHBondContact CD2-ND2 3.46Å; F396-N400 HydrophobicContact CE1-CB 3.55Å; F396-N400 HydrophobicContact CE2-CB 4.49Å; F396-N400 WeakPolarHBondContact CE2-ND2 3.44Å; F396-N400 HydrophobicContact CZ-CB 3.83Å; F396-N400 VanDerWaalsContact CZ-ND2 3.34Å; F396-N400 WeakPolarHBondContact CZ-ND2 3.42Å; F396-N400 WeakPolarHBondContact O-CB 3.22Å; F396-N400 PolarHBondContact O-N 2.9Å; F396-V456 HydrophobicContact CE2-CG1 3.87Å; F396-V456 HydrophobicContact CZ-CG1 4.05Å; F396-F457 HydrophobicContact CE1-CD2 4.35Å; F396-A460 HydrophobicContact CD1-CB 3.98Å; F396-A460 HydrophobicContact CE1-CB 3.53Å; F396-A460 HydrophobicContact CE2-CB 4.14Å; F396-A460 HydrophobicContact CG-CB 4.48Å; F396-A460 HydrophobicContact CZ-CB 3.62Å
397S94.8Very high94.7Very high3 Ų322.9 Ų22.92%0.02112%0.119CC..Hα-helixtrans-64.8-34.7178.374.90000112.1P393 F394 V399 A401P393-S397 PolarHBondContact O-N 2.91Å; P393-S397 VanDerWaalsContact O-N 3.07Å; F394-S397 PolarHBondContact O-N 3.38Å; F394-S397 VanDerWaalsContact O-N 3.13Å; F394-S397 PolarHBondContact O-OG 3Å; S397-V399 PolarHBondContact O-N 3.12Å; S397-V399 VanDerWaalsContact O-N 3.1Å; S397-A401 VanDerWaalsContact O-CB 3.24Å; S397-A401 WeakPolarHBondContact O-CB 3.32Å; S397-A401 PolarHBondContact O-N 2.84Å; S397-A401 VanDerWaalsContact O-N 3.14Å
398M95.5Very high94.5Very high0 Ų019 Ų190%010%0.099CC..Hα-helixtrans-56.7-29177.6-66.7-161.6-75.800114.2N301 G305 H337 W339 F394 V395 F396 V423N301-M398 PolarHBondContact ND2-O 2.89Å; G305-M398 PolarHBondContact N-O 3.44Å; G305-M398 VanDerWaalsContact O-CA 3.29Å; G305-M398 WeakPolarHBondContact O-CA 3.22Å; G305-M398 WeakPolarHBondContact O-CG 3.19Å; H337-M398 VanDerWaalsContact CD2-SD 3.58Å; W339-M398 HydrophobicContact CE3-CE 4.01Å; W339-M398 HydrophobicContact CE3-SD 4.2Å; W339-M398 HydrophobicContact CH2-CE 4.47Å; W339-M398 HydrophobicContact CZ3-CB 4.44Å; W339-M398 HydrophobicContact CZ3-CE 3.94Å; W339-M398 HydrophobicContact CZ3-SD 3.92Å; F394-M398 HydrophobicContact CD1-CE 4.26Å; F394-M398 HydrophobicContact CD1-SD 4.45Å; F394-M398 HydrophobicContact CE1-CE 4.13Å; F394-M398 HydrophobicContact CE1-CG 4.27Å; F394-M398 HydrophobicContact CE1-SD 3.86Å; F394-M398 HydrophobicContact CZ-CG 4.44Å; F394-M398 HydrophobicContact CZ-SD 4.31Å; F394-M398 WeakPolarHBondContact O-CG 3.45Å; F394-M398 PolarHBondContact O-N 3.28Å; F394-M398 VanDerWaalsContact O-N 3.15Å; V395-M398 HydrophobicContact CB-CE 4.09Å; V395-M398 HydrophobicContact CG1-CE 4.08Å; V395-M398 HydrophobicContact CG2-CE 3.92Å; V395-M398 PolarHBondContact O-N 3.39Å; F396-M398 VanDerWaalsContact C-N 3.29Å; F396-M398 PolarHBondContact O-N 3.19Å; M398-V423 WeakPolarHBondContact O-CG1 3.42Å
399V96.9Very high93.9Very high0 Ų022.4 Ų22.40%011%0.114CC..Hα-helixtrans-116.2-13.3-173.5-63.20000114.7W339 I381 F396 S397 I427 Y444 K445W339-V399 HydrophobicContact CH2-CG1 3.84Å; W339-V399 HydrophobicContact CZ2-CG1 4.4Å; I381-V399 HydrophobicContact CG2-CG2 3.76Å; F396-V399 PolarHBondContact O-N 2.8Å; S397-V399 PolarHBondContact O-N 3.12Å; S397-V399 VanDerWaalsContact O-N 3.1Å; V399-I427 HydrophobicContact CB-CD1 4.34Å; V399-I427 HydrophobicContact CG1-CD1 3.72Å; V399-Y444 HydrophobicContact CG1-CD1 4.1Å; V399-Y444 HydrophobicContact CG2-CD1 4.4Å; V399-K445 PolarHBondContact O-NZ 3.12Å; V399-K445 VanDerWaalsContact O-NZ 3.1Å
400N96.5Very high93.3Very high17 Ų1722 Ų229%0.09113%0.132CC..Hα-helixtrans-129.8-0.7-173.9-68.3-63.3000115.1F396 K445 F457F396-N400 HydrophobicContact CD1-CB 3.99Å; F396-N400 WeakPolarHBondContact CD2-ND2 3.46Å; F396-N400 HydrophobicContact CE1-CB 3.55Å; F396-N400 HydrophobicContact CE2-CB 4.49Å; F396-N400 WeakPolarHBondContact CE2-ND2 3.44Å; F396-N400 HydrophobicContact CZ-CB 3.83Å; F396-N400 VanDerWaalsContact CZ-ND2 3.34Å; F396-N400 WeakPolarHBondContact CZ-ND2 3.42Å; F396-N400 WeakPolarHBondContact O-CB 3.22Å; F396-N400 PolarHBondContact O-N 2.9Å; N400-K445 WeakPolarHBondContact OD1-CB 3.41Å; N400-F457 HydrophobicContact CB-CD2 4.34Å; N400-F457 WeakPolarHBondContact O-CD2 3.37Å; N400-F457 WeakPolarHBondContact O-CE2 3.36Å
401A93.9Very high92.5Very high2 Ų222.8 Ų22.82%0.01716%0.156CC..PPolyproline II helixtrans-62.8141.1-176.100000113.1L312 I314 S397 V423L312-A401 WeakPolarHBondContact O-CA 3.24Å; I314-A401 HydrophobicContact CD1-CB 3.75Å; I314-A401 HydrophobicContact CG1-CB 3.96Å; S397-A401 VanDerWaalsContact O-CB 3.24Å; S397-A401 WeakPolarHBondContact O-CB 3.32Å; S397-A401 PolarHBondContact O-N 2.84Å; S397-A401 VanDerWaalsContact O-N 3.14Å; A401-V423 HydrophobicContact CB-CG1 4.33Å; A401-V423 VanDerWaalsContact O-CB 3.24Å; A401-V423 WeakPolarHBondContact O-CB 3.4Å; A401-V423 WeakPolarHBondContact O-CG2 3.33Å
402D92.8Very high92Very high5 Ų529.1 Ų29.13%0.02718%0.181CC..EExtended strand (participates in β ladder)trans-76.4139.8171.3-76.8-13.9000109.1L312 I313 I314 Q418 T420 R454L312-D402 PolarHBondContact O-N 2.94Å; I313-D402 CarbonylContact C-O 3.55Å; I313-D402 VanDerWaalsContact CA-O 3.27Å; I313-D402 WeakPolarHBondContact CA-O 3.44Å; I314-D402 PolarHBondContact N-O 3.35Å; D402-Q418 PolarHBondContact OD2-NE2 3.07Å; D402-T420 VanDerWaalsContact OD1-CA 3.31Å; D402-T420 WeakPolarHBondContact OD1-CA 3.4Å; D402-T420 VanDerWaalsContact OD1-CB 3.27Å; D402-T420 WeakPolarHBondContact OD1-CB 2.87Å; D402-T420 WeakPolarHBondContact OD1-CG2 3.39Å; D402-R454 IonicContact OD1-NH1 3.52Å; D402-R454 IonicContact OD2-NH1 2.81Å; D402-R454 PolarHBondContact OD2-NH1 3.46Å; D402-R454 IonicContact OD2-NH2 2.8Å
403C90.7Very high91.7Very high6 Ų632.3 Ų32.34%0.04120%0.196CC..EExtended strand (participates in β ladder)trans-100.5131.3174.1-177.70000111.3I314 I333 Q418 D419I314-C403 WeakPolarHBondContact O-CA 3.37Å; I333-C403 HydrophobicContact CD1-CB 3.92Å; C403-Q418 WeakPolarHBondContact O-CA 3.16Å; C403-D419 HydrophobicContact CB-CB 4.38Å; C403-D419 PolarHBondContact N-O 3.38Å; C403-D419 PolarHBondContact O-N 2.94Å
404M90.7Very high91.5Very high17 Ų1733.4 Ų33.48%0.08420%0.197CC..EExtended strand (participates in β ladder)trans-117.3119.4179.7-71.9-75-65.500110.1I313 I314 D315 E316 W406 K415 Q418I313-M404 HydrophobicContact CG2-CB 4Å; I313-M404 HydrophobicContact CG2-CG 3.38Å; I314-M404 PolarHBondContact O-N 2.88Å; D315-M404 WeakPolarHBondContact CA-O 3.4Å; D315-M404 WeakPolarHBondContact OD1-CB 3.41Å; E316-M404 PolarHBondContact N-O 2.84Å; M404-W406 HydrophobicContact CB-CZ2 4.46Å; M404-W406 HydrophobicContact CE-CH2 4.06Å; M404-W406 HydrophobicContact CE-CZ2 3.56Å; M404-K415 HydrophobicContact CE-CD 3.5Å; M404-K415 HydrophobicContact CE-CG 3.96Å; M404-Q418 HydrophobicContact SD-CB 3.58Å; M404-Q418 VanDerWaalsContact SD-CB 3.58Å; M404-Q418 HydrophobicContact SD-CG 3.58Å; M404-Q418 VanDerWaalsContact SD-CG 3.58Å
405S90.3Very high91.2Very high7 Ų737 Ų375%0.04921%0.213CC..EExtended strand (participates in β ladder)trans-96.4132.9176.5-55.50000111E316 L416 H417E316-S405 CarbonylContact O-C 3.46Å; E316-S405 WeakPolarHBondContact O-CA 3.27Å; S405-L416 WeakPolarHBondContact O-CB 3.31Å; S405-L416 PolarHBondContact O-N 2.83Å; S405-H417 PolarHBondContact N-O 3.01Å; S405-H417 PolarHBondContact O-N 3.32Å
406W91.9Very high90.7Very high40 Ų4038.4 Ų38.415%0.15222%0.22CC..EExtended strand (participates in β ladder)trans-125138.1-177.8-57.692.4000111.3D315 E316 Y317 Y318 M404 E413 Q414 K415D315-W406 PolarHBondContact OD1-NE1 2.59Å; E316-W406 PolarHBondContact O-N 3.36Å; Y317-W406 CarbonylContact C-O 3.5Å; Y317-W406 WeakPolarHBondContact CA-O 3.29Å; Y317-W406 HydrophobicContact CD1-CB 3.61Å; Y317-W406 HydrophobicContact CD1-CG 4.17Å; Y317-W406 HydrophobicContact CE1-CB 3.82Å; Y317-W406 AromaticContact CE1-CD1 3.95Å; Y317-W406 AromaticContact CE1-CG 3.91Å; Y317-W406 HydrophobicContact CE1-CG 3.91Å; Y317-W406 HydrophobicContact CG-CB 4.47Å; Y318-W406 PolarHBondContact N-O 2.77Å; M404-W406 HydrophobicContact CB-CZ2 4.46Å; M404-W406 HydrophobicContact CE-CH2 4.06Å; M404-W406 HydrophobicContact CE-CZ2 3.56Å; W406-E413 HydrophobicContact CE3-CB 4.36Å; W406-Q414 CarbonylContact C-O 3.46Å; W406-Q414 WeakPolarHBondContact CA-O 3.09Å; W406-K415 HydrophobicContact CE3-CB 4.01Å; W406-K415 HydrophobicContact CH2-CB 4.28Å; W406-K415 HydrophobicContact CZ3-CB 3.72Å; W406-K415 HydrophobicContact CZ3-CG 4.49Å
407L91.7Very high90.1Very high1 Ų143.2 Ų43.21%0.00524%0.242CC..EExtended strand (participates in β ladder)trans-93.5130.1167.6-179.764000109.6Y318 D319 E413 Q414 L416 L599 K608Y318-L407 CarbonylContact O-C 3.51Å; Y318-L407 WeakPolarHBondContact O-CA 3.35Å; D319-L407 VanDerWaalsContact C-CD1 3.45Å; D319-L407 WeakPolarHBondContact O-CD1 3.2Å; L407-E413 CarbonylContact O-C 3.59Å; L407-E413 WeakPolarHBondContact O-CA 3.43Å; L407-Q414 HydrophobicContact CB-CB 4.36Å; L407-Q414 PolarHBondContact N-O 3.02Å; L407-Q414 PolarHBondContact O-N 2.59Å; L407-L416 HydrophobicContact CB-CD1 3.9Å; L407-L416 HydrophobicContact CB-CD2 3.83Å; L407-L416 HydrophobicContact CB-CG 3.81Å; L407-L416 HydrophobicContact CD2-CD2 4.47Å; L407-L599 HydrophobicContact CD1-CD2 3.88Å; L407-K608 HydrophobicContact CD2-CG 4.15Å
408V91.2Very high89.7Confident22 Ų2246.8 Ų46.813%0.13326%0.259CS..EExtended strand (participates in β ladder)trans-103.1111.4173.1-174.30000109Y317 Y318 L325 K328 K412 E413Y317-V408 HydrophobicContact CD1-CG2 3.79Å; Y317-V408 HydrophobicContact CG-CG2 4.4Å; Y318-V408 PolarHBondContact O-N 3.36Å; L325-V408 HydrophobicContact CD1-CB 3.83Å; L325-V408 HydrophobicContact CD1-CG1 4.42Å; L325-V408 HydrophobicContact CD1-CG2 3.85Å; K328-V408 HydrophobicContact CD-CG2 4.15Å; V408-K412 WeakPolarHBondContact CA-O 3.34Å; V408-E413 HydrophobicContact CG2-CG 4.35Å
409Q84.9Confident89.2Confident98 Ų9848.8 Ų48.846%0.45827%0.269SS..EExtended strand (participates in β ladder)trans-134.7123.9178.9-169.8178.113.100110.6G411 K412Q409-G411 PolarHBondContact O-N 3.42Å; Q409-K412 PolarHBondContact N-O 3.44Å; Q409-K412 PolarHBondContact O-N 3.18Å
410G82.6Confident88.8Confident85 Ų8551.5 Ų51.588%0.87629%0.286SS*.THydrogen-bonded Turntrans57.431.5179.300000113.8K412G410-K412 VanDerWaalsContact C-N 3.29Å; G410-K412 PolarHBondContact O-N 3Å
411G80.9Confident88.3Confident68 Ų6853.3 Ų53.370%0.70130%0.3SS*.THydrogen-bonded Turntrans80.7-2.7-176.300000115.5Q409Q409-G411 PolarHBondContact O-N 3.42Å
412K86.3Confident87.9Confident167 Ų16754 Ų5473%0.72631%0.305SS*.EExtended strand (participates in β ladder)trans-98.4149.6176.7-63.7-176.7179.7-179.90111.6V408 Q409 G410V408-K412 WeakPolarHBondContact CA-O 3.34Å; Q409-K412 PolarHBondContact N-O 3.44Å; Q409-K412 PolarHBondContact O-N 3.18Å; G410-K412 VanDerWaalsContact C-N 3.29Å; G410-K412 PolarHBondContact O-N 3Å
413E90.4Very high87.9Confident68 Ų6853.9 Ų53.932%0.31830%0.304SS..EExtended strand (participates in β ladder)trans-104.6125.6177.1-69.9168.1-173.900110.1Y317 K328 W406 L407 V408 R492Y317-E413 HydrophobicContact CE1-CG 4.14Å; K328-E413 IonicContact NZ-OE1 3.8Å; K328-E413 PolarHBondContact NZ-OE1 3.48Å; W406-E413 HydrophobicContact CE3-CB 4.36Å; L407-E413 CarbonylContact O-C 3.59Å; L407-E413 WeakPolarHBondContact O-CA 3.43Å; V408-E413 HydrophobicContact CG2-CG 4.35Å; E413-R492 IonicContact OE2-NH2 3.17Å; E413-R492 PolarHBondContact OE2-NH2 3.2Å
414Q89.8Confident88.1Confident76 Ų7653.6 Ų53.636%0.35530%0.302SS..EExtended strand (participates in β ladder)trans-118.4127.5175.9175.8-178.20.400109.2W406 L407 L416W406-Q414 CarbonylContact C-O 3.46Å; W406-Q414 WeakPolarHBondContact CA-O 3.09Å; L407-Q414 HydrophobicContact CB-CB 4.36Å; L407-Q414 PolarHBondContact N-O 3.02Å; L407-Q414 PolarHBondContact O-N 2.59Å; Q414-L416 PolarHBondContact O-N 3.31Å
415K89.1Confident88.3Confident96 Ų9654.3 Ų54.342%0.41731%0.306SS..EExtended strand (participates in β ladder)trans-64.4127.1174.6-175.3177.1176.91710109.4M404 W406M404-K415 HydrophobicContact CE-CD 3.5Å; M404-K415 HydrophobicContact CE-CG 3.96Å; W406-K415 HydrophobicContact CE3-CB 4.01Å; W406-K415 HydrophobicContact CH2-CB 4.28Å; W406-K415 HydrophobicContact CZ3-CB 3.72Å; W406-K415 HydrophobicContact CZ3-CG 4.49Å
416L85.8Confident88.6Confident29 Ų2957.8 Ų57.815%0.15232%0.321CS..EExtended strand (participates in β ladder)trans-97.5-52.7175.4-69.4177.1000111.3S405 L407 Q414 L599 K608 L610S405-L416 WeakPolarHBondContact O-CB 3.31Å; S405-L416 PolarHBondContact O-N 2.83Å; L407-L416 HydrophobicContact CB-CD1 3.9Å; L407-L416 HydrophobicContact CB-CD2 3.83Å; L407-L416 HydrophobicContact CB-CG 3.81Å; L407-L416 HydrophobicContact CD2-CD2 4.47Å; Q414-L416 PolarHBondContact O-N 3.31Å; L416-L599 HydrophobicContact CD1-CD1 4.26Å; L416-L599 HydrophobicContact CD2-CD1 4.38Å; L416-K608 HydrophobicContact CD2-CB 3.49Å; L416-K608 VanDerWaalsContact CD2-CB 3.49Å; L416-K608 HydrophobicContact CD2-CG 4.22Å; L416-L610 HydrophobicContact CD1-CB 4.3Å; L416-L610 HydrophobicContact CD1-CD2 4.06Å
417H85.1Confident88.9Confident100 Ų10055.9 Ų55.946%0.46331%0.314SS..EExtended strand (participates in β ladder)trans-153.9154.1-170.4-173.259000110.7S405S405-H417 PolarHBondContact N-O 3.01Å; S405-H417 PolarHBondContact O-N 3.32Å
418Q86.8Confident89.3Confident79 Ų7955.9 Ų55.937%0.36931%0.313SS..EExtended strand (participates in β ladder)trans-125.7124.2168.4177.2172.90.500107.3D402 C403 M404 T420D402-Q418 PolarHBondContact OD2-NE2 3.07Å; C403-Q418 WeakPolarHBondContact O-CA 3.16Å; M404-Q418 HydrophobicContact SD-CB 3.58Å; M404-Q418 VanDerWaalsContact SD-CB 3.58Å; M404-Q418 HydrophobicContact SD-CG 3.58Å; M404-Q418 VanDerWaalsContact SD-CG 3.58Å; Q418-T420 HydrophobicContact CG-CG2 4.17Å
419D85.8Confident89.6Confident41 Ų4155 Ų5522%0.21931%0.308CS..EExtended strand (participates in β ladder)trans-117.7117.6177.2-176.7-8.3000108.7C403 S421 S422C403-D419 HydrophobicContact CB-CB 4.38Å; C403-D419 PolarHBondContact N-O 3.38Å; C403-D419 PolarHBondContact O-N 2.94Å; D419-S421 PolarHBondContact OD1-N 3.09Å; D419-S421 PolarHBondContact OD1-OG 3.23Å; D419-S422 PolarHBondContact OD1-N 3.18Å; D419-S422 VanDerWaalsContact OD1-N 3.1Å; D419-S422 WeakPolarHBondContact OD2-CB 3.32Å; D419-S422 PolarHBondContact OD2-OG 3.23Å
420T88.2Confident90.3Very high58 Ų5850.8 Ų50.836%0.35629%0.288SS..SBendtrans-998.7-177.564.70000112.7D402 Q418D402-T420 VanDerWaalsContact OD1-CA 3.31Å; D402-T420 WeakPolarHBondContact OD1-CA 3.4Å; D402-T420 VanDerWaalsContact OD1-CB 3.27Å; D402-T420 WeakPolarHBondContact OD1-CB 2.87Å; D402-T420 WeakPolarHBondContact OD1-CG2 3.39Å; Q418-T420 HydrophobicContact CG-CG2 4.17Å
421S86.1Confident91Very high54 Ų5448 Ų4838%0.37826%0.255SS..SBendtrans-135.4-10.1-167.564.60000114.6D419 N425D419-S421 PolarHBondContact OD1-N 3.09Å; D419-S421 PolarHBondContact OD1-OG 3.23Å; S421-N425 PolarHBondContact O-ND2 3.22Å
422S84.9Confident91.7Very high18 Ų1847.5 Ų47.513%0.12624%0.236CC..SBendtrans-76.1-23.1-176.841.90000115D303 D419 N425D303-S422 WeakPolarHBondContact CB-O 3.33Å; D419-S422 PolarHBondContact OD1-N 3.18Å; D419-S422 VanDerWaalsContact OD1-N 3.1Å; D419-S422 WeakPolarHBondContact OD2-CB 3.32Å; D419-S422 PolarHBondContact OD2-OG 3.23Å; S422-N425 PolarHBondContact O-ND2 3.1Å
423V92.6Very high91.8Very high2 Ų246.2 Ų46.21%0.01223%0.232CC..SBendtrans-85.2138.7-178.3173.60000110.2D303 I314 I333 M398 A401 K445D303-V423 VanDerWaalsContact O-CA 3.3Å; D303-V423 WeakPolarHBondContact O-CA 3.04Å; I314-V423 HydrophobicContact CD1-CG2 4.23Å; I333-V423 HydrophobicContact CD1-CG2 4.04Å; I333-V423 HydrophobicContact CG1-CG2 4.48Å; M398-V423 WeakPolarHBondContact O-CG1 3.42Å; A401-V423 HydrophobicContact CB-CG1 4.33Å; A401-V423 VanDerWaalsContact O-CB 3.24Å; A401-V423 WeakPolarHBondContact O-CB 3.4Å; A401-V423 WeakPolarHBondContact O-CG2 3.33Å; V423-K445 PolarHBondContact O-NZ 3.43Å
424G95Very high91.9Very high0 Ų045 Ų450%023%0.232CC..SBendtrans78.265.4171.500000114.1N301 D303 K445N301-G424 WeakPolarHBondContact OD1-CA 3.15Å; D303-G424 PolarHBondContact O-N 2.96Å; G424-K445 WeakPolarHBondContact O-CE 3.47Å; G424-K445 PolarHBondContact O-NZ 2.65Å
425N94.6Very high92.1Very high32 Ų3243.3 Ų43.317%0.17123%0.225CC..EExtended strand (participates in β ladder)trans-116149.4-173.4-82-80.7000112.7K173 N301 F302 S421 S422 I427K173-N425 HydrophobicContact CB-CB 4.49Å; K173-N425 HydrophobicContact CD-CB 4.49Å; N301-N425 PolarHBondContact OD1-N 2.75Å; F302-N425 WeakPolarHBondContact CB-O 3.42Å; F302-N425 PolarHBondContact N-O 3.34Å; F302-N425 PolarHBondContact O-N 2.53Å; S421-N425 PolarHBondContact O-ND2 3.22Å; S422-N425 PolarHBondContact O-ND2 3.1Å; N425-I427 PolarHBondContact O-N 2.92Å; N425-I427 VanDerWaalsContact O-N 3.14Å
426F97Very high92.5Very high80 Ų8045.2 Ų45.235%0.35124%0.236SC..EExtended strand (participates in β ladder)trans42.650.2175.4-57.1-77.2000112.9K173 I176 F302 S428 D439 T441K173-F426 HydrophobicContact CB-CD2 3.62Å; K173-F426 HydrophobicContact CB-CE2 3.8Å; K173-F426 HydrophobicContact CD-CE2 4.49Å; K173-F426 WeakPolarHBondContact O-CE2 3.43Å; I176-F426 HydrophobicContact CD1-CB 3.62Å; I176-F426 HydrophobicContact CD1-CD2 4.44Å; I176-F426 HydrophobicContact CD1-CG 3.96Å; F302-F426 HydrophobicContact CD2-CB 4.03Å; F302-F426 WeakPolarHBondContact CD2-O 2.98Å; F426-S428 WeakPolarHBondContact O-CB 3.21Å; F426-S428 PolarHBondContact O-N 3.17Å; F426-S428 PolarHBondContact O-OG 3.48Å; F426-D439 WeakPolarHBondContact CA-OD2 3.28Å; F426-D439 WeakPolarHBondContact CD1-OD2 3.43Å; F426-T441 WeakPolarHBondContact CA-OG1 3.08Å; F426-T441 PolarHBondContact N-OG1 3.18Å
427I98.6Very high93.1Very high0 Ų047.9 Ų47.90%024%0.244CC..EExtended strand (participates in β ladder)trans-60.6114.6-179.2-56177.2000107.3I299 T300 N301 V399 N425 I440 T441 Y444I299-I427 HydrophobicContact CG2-CG2 3.35Å; T300-I427 CarbonylContact O-C 3.59Å; T300-I427 VanDerWaalsContact O-CA 3.28Å; T300-I427 WeakPolarHBondContact O-CA 3.38Å; N301-I427 HydrophobicContact CB-CG1 4.41Å; N301-I427 WeakPolarHBondContact OD1-CG1 3.4Å; V399-I427 HydrophobicContact CB-CD1 4.34Å; V399-I427 HydrophobicContact CG1-CD1 3.72Å; N425-I427 PolarHBondContact O-N 2.92Å; N425-I427 VanDerWaalsContact O-N 3.14Å; I427-I440 HydrophobicContact CB-CG1 4.31Å; I427-I440 HydrophobicContact CG2-CD1 4.23Å; I427-I440 HydrophobicContact CG2-CG1 3.87Å; I427-I440 VanDerWaalsContact O-CG1 3.29Å; I427-I440 WeakPolarHBondContact O-CG1 3.46Å; I427-I440 PolarHBondContact O-N 2.98Å; I427-T441 HydrophobicContact CD1-CG2 4.4Å; I427-T441 HydrophobicContact CG1-CG2 4.37Å; I427-T441 PolarHBondContact N-OG1 2.98Å; I427-Y444 HydrophobicContact CD1-CD1 4.26Å; I427-Y444 HydrophobicContact CD1-CD2 3.81Å; I427-Y444 HydrophobicContact CD1-CG 3.63Å; I427-Y444 HydrophobicContact CG2-CD2 3.98Å; I427-Y444 HydrophobicContact CG2-CE2 3.87Å
428S98.7Very high93.7Very high0 Ų044.4 Ų44.40%023%0.232CC..EExtended strand (participates in β ladder)trans-123.1141.6-160.5-670000112.2I299 T300 F426 R437 A438I299-S428 WeakPolarHBondContact CA-O 3.48Å; T300-S428 PolarHBondContact N-O 3.37Å; T300-S428 PolarHBondContact O-N 3.45Å; F426-S428 WeakPolarHBondContact O-CB 3.21Å; F426-S428 PolarHBondContact O-N 3.17Å; F426-S428 PolarHBondContact O-OG 3.48Å; S428-R437 WeakPolarHBondContact OG-CD 3.43Å; S428-R437 PolarHBondContact OG-NH1 2.82Å; S428-A438 WeakPolarHBondContact CA-O 3.32Å
429T98.8Very high94.2Very high3 Ų343.6 Ų43.62%0.01823%0.23CC..EExtended strand (participates in β ladder)trans-139163.5169.1179.70000109.9Y169 V298 I299 A438 I440Y169-T429 WeakPolarHBondContact CE2-O 3.46Å; V298-T429 PolarHBondContact O-OG1 2.74Å; I299-T429 HydrophobicContact CD1-CG2 4.31Å; T429-A438 HydrophobicContact CG2-CB 4.07Å; T429-A438 PolarHBondContact N-O 2.88Å; T429-A438 PolarHBondContact O-N 2.88Å; T429-I440 HydrophobicContact CG2-CD1 4.21Å; T429-I440 HydrophobicContact CG2-CG1 4.47Å; T429-I440 HydrophobicContact CG2-CG2 3.93Å
430K98.4Very high94.8Very high10 Ų1042.1 Ų42.14%0.04322%0.222CC..EExtended strand (participates in β ladder)trans-65.7138.8170.8-178-178.4170-62.40109.4E159 F167 S434E159-K430 WeakPolarHBondContact OE1-CD 3.5Å; E159-K430 IonicContact OE1-NZ 3.74Å; E159-K430 PolarHBondContact OE1-NZ 3.4Å; E159-K430 IonicContact OE2-NZ 3.97Å; E159-K430 PolarHBondContact OE2-NZ 3.03Å; F167-K430 HydrophobicContact CD2-CD 3.79Å; F167-K430 HydrophobicContact CD2-CG 4.1Å; F167-K430 HydrophobicContact CE2-CD 4.41Å; K430-S434 WeakPolarHBondContact CE-O 3.31Å; K430-S434 PolarHBondContact NZ-O 2.73Å
431S97.3Very high95.3Very high26 Ų2640.6 Ų40.618%0.18221%0.213CC..PPolyproline II helixtrans-71.2151.5175.1-59.40000111.8Q433 S434 E436 A438S431-Q433 PolarHBondContact O-N 3.42Å; S431-S434 PolarHBondContact O-N 2.65Å; S431-E436 WeakPolarHBondContact CB-O 3.39Å; S431-E436 PolarHBondContact N-O 2.79Å; S431-E436 PolarHBondContact OG-O 3.23Å; S431-A438 WeakPolarHBondContact OG-CB 3.48Å; S431-A438 PolarHBondContact OG-N 3.34Å
432I96.7Very high95.9Very high58 Ų5844.8 Ų44.830%0.29723%0.227SC..THydrogen-bonded Turntrans-63.4128.9175-61.4152.9000109P155 Q156 E159 Y160 S434P155-I432 HydrophobicContact CB-CG2 3.75Å; P155-I432 WeakPolarHBondContact O-CG2 3.35Å; Q156-I432 HydrophobicContact CG-CD1 3.53Å; Q156-I432 HydrophobicContact CG-CG1 4.23Å; E159-I432 HydrophobicContact CB-CB 4.49Å; E159-I432 HydrophobicContact CB-CG1 4.42Å; E159-I432 HydrophobicContact CB-CG2 4.21Å; E159-I432 HydrophobicContact CG-CG1 4.45Å; Y160-I432 HydrophobicContact CE2-CD1 4.49Å; Y160-I432 HydrophobicContact CE2-CG1 4.27Å; Y160-I432 WeakPolarHBondContact OH-CG1 3.37Å; I432-S434 PolarHBondContact O-N 2.81Å
433Q88.2Confident96.6Very high140 Ų14046.7 Ų46.765%0.65424%0.236SC*.THydrogen-bonded Turntrans56.718.4175.7-63.9177.2-30.700115.1S431S431-Q433 PolarHBondContact O-N 3.42Å
434S93.3Very high96.8Very high44 Ų4446.6 Ų46.631%0.30824%0.235SC..SBendtrans-142.5156.2179.5176.30000110.8K430 S431 I432 E436K430-S434 WeakPolarHBondContact CE-O 3.31Å; K430-S434 PolarHBondContact NZ-O 2.73Å; S431-S434 PolarHBondContact O-N 2.65Å; I432-S434 PolarHBondContact O-N 2.81Å; S434-E436 VanDerWaalsContact C-N 3.27Å; S434-E436 WeakPolarHBondContact OG-CB 3.25Å; S434-E436 WeakPolarHBondContact OG-CG 3.28Å; S434-E436 PolarHBondContact OG-N 3.44Å; S434-E436 VanDerWaalsContact OG-N 3.12Å
435D93.9Very high97Very high40 Ų4047.1 Ų47.121%0.21424%0.237CC..SBendtrans-87-1.2173.7-70.2-3.8000112.2F167 N713F167-D435 HydrophobicContact CD2-CB 4.42Å; F167-D435 HydrophobicContact CE2-CB 3.52Å; F167-D435 VanDerWaalsContact CE2-CG 3.43Å; F167-D435 WeakPolarHBondContact CE2-OD1 3.46Å; F167-D435 HydrophobicContact CZ-CB 4.06Å; D435-N713 PolarHBondContact OD2-ND2 2.8Å
436E96.7Very high97.1Very high136 Ų13648.8 Ų48.864%0.63624%0.242SC*.SBendtrans-73.8155178.8-67.1-62.5157.800113.1Y169 S431 S434Y169-E436 PolarHBondContact OH-O 2.78Å; S431-E436 WeakPolarHBondContact CB-O 3.39Å; S431-E436 PolarHBondContact N-O 2.79Å; S431-E436 PolarHBondContact OG-O 3.23Å; S434-E436 VanDerWaalsContact C-N 3.27Å; S434-E436 WeakPolarHBondContact OG-CB 3.25Å; S434-E436 WeakPolarHBondContact OG-CG 3.28Å; S434-E436 PolarHBondContact OG-N 3.44Å; S434-E436 VanDerWaalsContact OG-N 3.12Å
437R97.7Very high97Very high84 Ų8452.8 Ų52.832%0.31726%0.261SS..EExtended strand (participates in β ladder)trans-76.8126.8174.1-169.9-174.273.885.22.7111.2Y169 S428 D439Y169-R437 HydrophobicContact CD1-CB 4.31Å; Y169-R437 HydrophobicContact CD1-CG 3.92Å; Y169-R437 HydrophobicContact CD2-CG 4.37Å; Y169-R437 HydrophobicContact CE1-CB 3.53Å; Y169-R437 HydrophobicContact CE1-CG 3.59Å; Y169-R437 HydrophobicContact CE2-CB 4.49Å; Y169-R437 HydrophobicContact CE2-CG 4.12Å; Y169-R437 HydrophobicContact CG-CG 4.29Å; Y169-R437 WeakPolarHBondContact OH-CA 3.46Å; Y169-R437 PolarHBondContact OH-N 2.85Å; S428-R437 WeakPolarHBondContact OG-CD 3.43Å; S428-R437 PolarHBondContact OG-NH1 2.82Å; R437-D439 IonicContact CZ-OD2 3.71Å; R437-D439 IonicContact NH1-OD2 3.67Å; R437-D439 PolarHBondContact NH1-OD2 3.09Å; R437-D439 IonicContact NH2-OD2 3.39Å; R437-D439 PolarHBondContact NH2-OD2 3.49Å
438A98.3Very high96.6Very high27 Ų2755.5 Ų55.522%0.22327%0.274CS..EExtended strand (participates in β ladder)trans-96.1123.6164.800000109.2S428 T429 S431S428-A438 WeakPolarHBondContact CA-O 3.32Å; T429-A438 HydrophobicContact CG2-CB 4.07Å; T429-A438 PolarHBondContact N-O 2.88Å; T429-A438 PolarHBondContact O-N 2.88Å; S431-A438 WeakPolarHBondContact OG-CB 3.48Å; S431-A438 PolarHBondContact OG-N 3.34Å
439D98.4Very high96.1Very high62 Ų6259 Ų5933%0.33231%0.31SS..EExtended strand (participates in β ladder)trans-84.9125168.3-156.1-56.5000109.3F426 R437 T441F426-D439 WeakPolarHBondContact CA-OD2 3.28Å; F426-D439 WeakPolarHBondContact CD1-OD2 3.43Å; R437-D439 IonicContact CZ-OD2 3.71Å; R437-D439 IonicContact NH1-OD2 3.67Å; R437-D439 PolarHBondContact NH1-OD2 3.09Å; R437-D439 IonicContact NH2-OD2 3.39Å; R437-D439 PolarHBondContact NH2-OD2 3.49Å; D439-T441 VanDerWaalsContact OD1-CB 3.28Å; D439-T441 WeakPolarHBondContact OD1-CB 3.07Å; D439-T441 PolarHBondContact OD1-N 3.45Å; D439-T441 PolarHBondContact OD1-OG1 3.2Å
440I98.6Very high95.9Very high10 Ų1060.1 Ų60.15%0.05132%0.318CS..  trans-122.520.1-179.363163.4000111.7I299 I427 T429 E442 N443 Y444I299-I440 HydrophobicContact CD1-CD1 3.54Å; I299-I440 HydrophobicContact CG1-CD1 4.38Å; I299-I440 HydrophobicContact CG2-CD1 4.36Å; I427-I440 HydrophobicContact CB-CG1 4.31Å; I427-I440 HydrophobicContact CG2-CD1 4.23Å; I427-I440 HydrophobicContact CG2-CG1 3.87Å; I427-I440 VanDerWaalsContact O-CG1 3.29Å; I427-I440 WeakPolarHBondContact O-CG1 3.46Å; I427-I440 PolarHBondContact O-N 2.98Å; T429-I440 HydrophobicContact CG2-CD1 4.21Å; T429-I440 HydrophobicContact CG2-CG1 4.47Å; T429-I440 HydrophobicContact CG2-CG2 3.93Å; I440-E442 PolarHBondContact O-N 2.62Å; I440-N443 VanDerWaalsContact O-CB 3.28Å; I440-N443 WeakPolarHBondContact O-CB 3.42Å; I440-N443 PolarHBondContact O-N 2.88Å; I440-Y444 HydrophobicContact CD1-CE2 3.96Å
441T98.5Very high95.7Very high27 Ų2766.1 Ų66.117%0.16635%0.35CS..Hα-helixtrans-54.7-40.1-179.2-52.30000111.8F426 I427 D439 N443 Y444 K445F426-T441 WeakPolarHBondContact CA-OG1 3.08Å; F426-T441 PolarHBondContact N-OG1 3.18Å; I427-T441 HydrophobicContact CD1-CG2 4.4Å; I427-T441 HydrophobicContact CG1-CG2 4.37Å; I427-T441 PolarHBondContact N-OG1 2.98Å; D439-T441 VanDerWaalsContact OD1-CB 3.28Å; D439-T441 WeakPolarHBondContact OD1-CB 3.07Å; D439-T441 PolarHBondContact OD1-N 3.45Å; D439-T441 PolarHBondContact OD1-OG1 3.2Å; T441-N443 PolarHBondContact O-N 2.93Å; T441-N443 VanDerWaalsContact O-N 3.1Å; T441-Y444 PolarHBondContact O-N 3.27Å; T441-K445 HydrophobicContact CG2-CG 4.26Å; T441-K445 PolarHBondContact O-N 3.46Å
442E98.2Very high95.7Very high141 Ų14169.6 Ų69.666%0.65936%0.363SS*.Hα-helixtrans-62.9-16.3177.664.2174.7-162.300114.3K382 I440 K445K382-E442 VanDerWaalsContact CE-O 3.31Å; K382-E442 WeakPolarHBondContact CE-O 3.27Å; K382-E442 PolarHBondContact NZ-O 3.35Å; I440-E442 PolarHBondContact O-N 2.62Å; E442-K445 WeakPolarHBondContact CA-O 3.28Å
443N98.6Very high95.7Very high59 Ų5967.5 Ų67.532%0.31635%0.352SS..Hα-helixtrans-78.9-23.5174.5-66.6-25.2000112.3V378 K382 I440 T441V378-N443 HydrophobicContact CG1-CB 4.13Å; V378-N443 VanDerWaalsContact CG1-O 3.28Å; V378-N443 WeakPolarHBondContact CG1-O 3.39Å; K382-N443 WeakPolarHBondContact CB-O 3.46Å; I440-N443 VanDerWaalsContact O-CB 3.28Å; I440-N443 WeakPolarHBondContact O-CB 3.42Å; I440-N443 PolarHBondContact O-N 2.88Å; T441-N443 PolarHBondContact O-N 2.93Å; T441-N443 VanDerWaalsContact O-N 3.1Å
444Y98.7Very high96Very high0 Ų064.6 Ų64.60%034%0.335CS..Hα-helixtrans-99.6-29.3-176.9-80-99.6000113.6W339 E341 V358 V378 I381 K382 V399 I427 I440 T441W339-Y444 HydrophobicContact CZ2-CD1 4.43Å; W339-Y444 AromaticContact CZ2-CE1 3.65Å; W339-Y444 HydrophobicContact CZ2-CE1 3.65Å; W339-Y444 AromaticContact CZ2-CZ 3.85Å; W339-Y444 AromaticContact NE1-CZ 3.89Å; W339-Y444 PolarHBondContact NE1-OH 3.47Å; E341-Y444 WeakPolarHBondContact CG-OH 3.49Å; E341-Y444 WeakPolarHBondContact OE1-CE2 3.48Å; E341-Y444 PolarHBondContact OE1-OH 2.82Å; V358-Y444 HydrophobicContact CG2-CE1 3.73Å; V358-Y444 WeakPolarHBondContact CG2-OH 3.17Å; V378-Y444 HydrophobicContact CG1-CD2 4.15Å; V378-Y444 HydrophobicContact CG1-CE1 4.47Å; V378-Y444 HydrophobicContact CG1-CE2 4.04Å; V378-Y444 HydrophobicContact CG1-CG 4.39Å; V378-Y444 HydrophobicContact CG2-CE1 4.38Å; V378-Y444 HydrophobicContact CG2-CE2 4.47Å; I381-Y444 HydrophobicContact CG2-CD1 4.19Å; K382-Y444 WeakPolarHBondContact CA-O 3.45Å; K382-Y444 PolarHBondContact N-O 3.42Å; V399-Y444 HydrophobicContact CG1-CD1 4.1Å; V399-Y444 HydrophobicContact CG2-CD1 4.4Å; I427-Y444 HydrophobicContact CD1-CD1 4.26Å; I427-Y444 HydrophobicContact CD1-CD2 3.81Å; I427-Y444 HydrophobicContact CD1-CG 3.63Å; I427-Y444 HydrophobicContact CG2-CD2 3.98Å; I427-Y444 HydrophobicContact CG2-CE2 3.87Å; I440-Y444 HydrophobicContact CD1-CE2 3.96Å; T441-Y444 PolarHBondContact O-N 3.27Å
445K97.8Very high96.2Very high10 Ų1068.5 Ų68.54%0.04335%0.349CS..SBendtrans-152.4160.9-17959.9179.1178.3-179.10112.1V399 N400 V423 G424 T441 E442 E448V399-K445 PolarHBondContact O-NZ 3.12Å; V399-K445 VanDerWaalsContact O-NZ 3.1Å; N400-K445 WeakPolarHBondContact OD1-CB 3.41Å; V423-K445 PolarHBondContact O-NZ 3.43Å; G424-K445 WeakPolarHBondContact O-CE 3.47Å; G424-K445 PolarHBondContact O-NZ 2.65Å; T441-K445 HydrophobicContact CG2-CG 4.26Å; T441-K445 PolarHBondContact O-N 3.46Å; E442-K445 WeakPolarHBondContact CA-O 3.28Å; K445-E448 VanDerWaalsContact CE-OE1 3.29Å; K445-E448 WeakPolarHBondContact CE-OE1 3.35Å; K445-E448 IonicContact NZ-OE1 3.55Å; K445-E448 PolarHBondContact NZ-OE1 3.26Å
446Y97.8Very high96.4Very high67 Ų6767.4 Ų67.426%0.26334%0.343SS..PPolyproline II helixtrans-74.2165171.3-68.2-82.7000110.5K382 E383 E448 Q452 V456K382-Y446 HydrophobicContact CG-CD2 4.43Å; K382-Y446 HydrophobicContact CG-CE2 4.06Å; K382-Y446 WeakPolarHBondContact O-CE2 3.41Å; E383-Y446 VanDerWaalsContact CD-OH 3.29Å; E383-Y446 PolarHBondContact OE1-OH 3.28Å; E383-Y446 PolarHBondContact OE2-OH 3.15Å; Y446-E448 PolarHBondContact O-N 2.97Å; Y446-Q452 HydrophobicContact CD1-CB 3.92Å; Y446-Q452 HydrophobicContact CD2-CB 4.26Å; Y446-Q452 HydrophobicContact CE1-CB 4.37Å; Y446-Q452 HydrophobicContact CG-CB 3.84Å; Y446-V456 HydrophobicContact CD2-CG2 3.77Å; Y446-V456 HydrophobicContact CE2-CG2 3.6Å
447E94.8Very high96.4Very high164 Ų16461.2 Ų61.277%0.76631%0.314SS*.PPolyproline II helixtrans-58.3130.7179.8-173.3178.8-175.500111.1G449 S450 E453E447-G449 PolarHBondContact O-N 3.2Å; E447-S450 WeakPolarHBondContact O-CB 3.15Å; E447-S450 PolarHBondContact O-N 2.68Å; E447-S450 PolarHBondContact O-OG 2.96Å; E447-E453 WeakPolarHBondContact O-CB 3.14Å
448E90.1Very high96.3Very high58 Ų5861.4 Ų61.427%0.27132%0.321SS..THydrogen-bonded Turntrans-55.5131.7178.8-71-65.6168.300111.6K445 Y446 S450K445-E448 VanDerWaalsContact CE-OE1 3.29Å; K445-E448 WeakPolarHBondContact CE-OE1 3.35Å; K445-E448 IonicContact NZ-OE1 3.55Å; K445-E448 PolarHBondContact NZ-OE1 3.26Å; Y446-E448 PolarHBondContact O-N 2.97Å; E448-S450 VanDerWaalsContact C-N 3.27Å; E448-S450 PolarHBondContact O-N 2.81Å
449G88.1Confident96.2Very high73 Ų7363.4 Ų63.475%0.75333%0.325SS*.THydrogen-bonded Turntrans80.9-2.2-176.800000115.1E447E447-G449 PolarHBondContact O-N 3.2Å
450S94Very high96.1Very high26 Ų2660.4 Ų60.418%0.18231%0.309CS..SBendtrans-71.9156.6169.471.20000111.8E447 E448 Q452 E453E447-S450 WeakPolarHBondContact O-CB 3.15Å; E447-S450 PolarHBondContact O-N 2.68Å; E447-S450 PolarHBondContact O-OG 2.96Å; E448-S450 VanDerWaalsContact C-N 3.27Å; E448-S450 PolarHBondContact O-N 2.81Å; S450-Q452 PolarHBondContact O-N 2.87Å; S450-E453 WeakPolarHBondContact OG-CB 3.27Å; S450-E453 PolarHBondContact OG-N 3.46Å
451L94.8Very high95.9Very high136 Ų13661.4 Ų61.471%0.71231%0.314SS*.Hα-helixtrans-64-33.8175.2-70.4174.3000111.8Q455L451-Q455 WeakPolarHBondContact O-CB 3.36Å; L451-Q455 WeakPolarHBondContact O-CG 3.11Å; L451-Q455 PolarHBondContact O-N 3.26Å
452Q96.5Very high95.7Very high99 Ų9967 Ų6746%0.46334%0.338SS..Hα-helixtrans-67.1-45.7-178.6-67.484.3-17.500111.5Y446 S450 R454 Q455 V456Y446-Q452 HydrophobicContact CD1-CB 3.92Å; Y446-Q452 HydrophobicContact CD2-CB 4.26Å; Y446-Q452 HydrophobicContact CE1-CB 4.37Å; Y446-Q452 HydrophobicContact CG-CB 3.84Å; S450-Q452 PolarHBondContact O-N 2.87Å; Q452-R454 VanDerWaalsContact C-N 3.35Å; Q452-R454 PolarHBondContact O-N 2.95Å; Q452-Q455 PolarHBondContact O-N 3.44Å; Q452-V456 WeakPolarHBondContact O-CG2 3.44Å; Q452-V456 PolarHBondContact O-N 3.33Å
453E96.1Very high95.6Very high15 Ų1563 Ų637%0.0732%0.319CS..Hα-helixtrans-51.3-55.2174.8168-80131.700110.2E447 S450 Q455 V456 F457E447-E453 WeakPolarHBondContact O-CB 3.14Å; S450-E453 WeakPolarHBondContact OG-CB 3.27Å; S450-E453 PolarHBondContact OG-N 3.46Å; E453-Q455 VanDerWaalsContact C-N 3.34Å; E453-Q455 PolarHBondContact O-N 3Å; E453-V456 PolarHBondContact O-N 3.29Å; E453-F457 PolarHBondContact O-N 3.45Å
454R95.1Very high95.2Very high78 Ų7861.5 Ų61.529%0.29431%0.311SS..Hα-helixtrans-68-34.5-176.4-165.665.4-166.1172.9-0.9113.3D402 Q452 F457 L458D402-R454 IonicContact OD1-NH1 3.52Å; D402-R454 IonicContact OD2-NH1 2.81Å; D402-R454 PolarHBondContact OD2-NH1 3.46Å; D402-R454 IonicContact OD2-NH2 2.8Å; Q452-R454 VanDerWaalsContact C-N 3.35Å; Q452-R454 PolarHBondContact O-N 2.95Å; R454-F457 VanDerWaalsContact CZ-CD1 3.43Å; R454-F457 VanDerWaalsContact NH1-CD1 3.27Å; R454-F457 PolarHBondContact O-N 3.1Å; R454-L458 HydrophobicContact CG-CD1 4.24Å; R454-L458 HydrophobicContact CG-CG 4.45Å; R454-L458 WeakPolarHBondContact O-CB 3.34Å; R454-L458 VanDerWaalsContact O-CG 3.27Å; R454-L458 WeakPolarHBondContact O-CG 3.19Å; R454-L458 PolarHBondContact O-N 2.91Å
455Q97.4Very high94.7Very high127 Ų12766.2 Ų66.259%0.59333%0.331SS*.Hα-helixtrans-61.8-43.9174.6-77.9171.5-000111.7L451 Q452 E453 L458 K459L451-Q455 WeakPolarHBondContact O-CB 3.36Å; L451-Q455 WeakPolarHBondContact O-CG 3.11Å; L451-Q455 PolarHBondContact O-N 3.26Å; Q452-Q455 PolarHBondContact O-N 3.44Å; E453-Q455 VanDerWaalsContact C-N 3.34Å; E453-Q455 PolarHBondContact O-N 3Å; Q455-L458 PolarHBondContact O-N 2.97Å; Q455-K459 WeakPolarHBondContact O-CB 3.46Å; Q455-K459 PolarHBondContact O-N 3.3Å
456V97.7Very high94.1Very high17 Ų1768.2 Ų68.210%0.10335%0.35CS..Hα-helixtrans-64.1-45.4176.71680000111.2K382 F396 Y446 Q452 E453 L458 K459 A460K382-V456 WeakPolarHBondContact O-CG1 3.28Å; F396-V456 HydrophobicContact CE2-CG1 3.87Å; F396-V456 HydrophobicContact CZ-CG1 4.05Å; Y446-V456 HydrophobicContact CD2-CG2 3.77Å; Y446-V456 HydrophobicContact CE2-CG2 3.6Å; Q452-V456 WeakPolarHBondContact O-CG2 3.44Å; Q452-V456 PolarHBondContact O-N 3.33Å; E453-V456 PolarHBondContact O-N 3.29Å; V456-L458 PolarHBondContact O-N 3.12Å; V456-K459 WeakPolarHBondContact O-CB 3.22Å; V456-K459 PolarHBondContact O-N 3.27Å; V456-A460 PolarHBondContact O-N 3.11Å
457F96.5Very high93Very high5 Ų567.1 Ų67.12%0.02236%0.358CS..Hα-helixtrans-57.6-48.3176.1-178.4-86.7000111.9L312 F396 N400 E453 R454 K459 A460 L461L312-F457 HydrophobicContact CB-CE2 3.96Å; L312-F457 HydrophobicContact CB-CZ 3.89Å; L312-F457 HydrophobicContact CD1-CE2 4.17Å; L312-F457 HydrophobicContact CD1-CZ 4.33Å; F396-F457 HydrophobicContact CE1-CD2 4.35Å; N400-F457 HydrophobicContact CB-CD2 4.34Å; N400-F457 WeakPolarHBondContact O-CD2 3.37Å; N400-F457 WeakPolarHBondContact O-CE2 3.36Å; E453-F457 PolarHBondContact O-N 3.45Å; R454-F457 VanDerWaalsContact CZ-CD1 3.43Å; R454-F457 VanDerWaalsContact NH1-CD1 3.27Å; R454-F457 PolarHBondContact O-N 3.1Å; F457-K459 VanDerWaalsContact C-N 3.34Å; F457-K459 PolarHBondContact O-N 3.46Å; F457-A460 PolarHBondContact O-N 3.4Å; F457-L461 HydrophobicContact CE1-CD2 4.38Å; F457-L461 WeakPolarHBondContact O-CB 3.48Å; F457-L461 PolarHBondContact O-N 2.97Å
458L95.8Very high91.7Very high89 Ų8964.9 Ų64.947%0.46634%0.343SS..Hα-helixtrans-65.2-37.6179.6-70.3173.9000112.4R454 Q455 V456 L461 Q462R454-L458 HydrophobicContact CG-CD1 4.24Å; R454-L458 HydrophobicContact CG-CG 4.45Å; R454-L458 WeakPolarHBondContact O-CB 3.34Å; R454-L458 VanDerWaalsContact O-CG 3.27Å; R454-L458 WeakPolarHBondContact O-CG 3.19Å; R454-L458 PolarHBondContact O-N 2.91Å; Q455-L458 PolarHBondContact O-N 2.97Å; V456-L458 PolarHBondContact O-N 3.12Å; L458-L461 PolarHBondContact O-N 3.35Å; L458-Q462 WeakPolarHBondContact O-CB 3.46Å; L458-Q462 PolarHBondContact O-N 3.45Å
459K97.3Very high90.1Very high68 Ų6869 Ų6930%0.29636%0.36SS..Hα-helixtrans-59.3-50.2173173.8-171.4173.1-170.80110.9E383 E385 Q455 V456 F457 L461 Q462 K463E383-K459 WeakPolarHBondContact O-CE 3.43Å; E383-K459 PolarHBondContact O-NZ 3.39Å; E385-K459 WeakPolarHBondContact OE1-CE 3.19Å; E385-K459 IonicContact OE1-NZ 3.69Å; E385-K459 PolarHBondContact OE1-NZ 2.95Å; E385-K459 IonicContact OE2-NZ 3.51Å; Q455-K459 WeakPolarHBondContact O-CB 3.46Å; Q455-K459 PolarHBondContact O-N 3.3Å; V456-K459 WeakPolarHBondContact O-CB 3.22Å; V456-K459 PolarHBondContact O-N 3.27Å; F457-K459 VanDerWaalsContact C-N 3.34Å; F457-K459 PolarHBondContact O-N 3.46Å; K459-L461 PolarHBondContact O-N 3.24Å; K459-Q462 PolarHBondContact O-N 3.41Å; K459-K463 WeakPolarHBondContact O-CG 3.48Å; K459-K463 PolarHBondContact O-N 2.99Å; K459-K463 VanDerWaalsContact O-N 3.07Å
460A96.8Very high88.2Confident0 Ų072.1 Ų72.10%036%0.355CS..Hα-helixtrans-59.2-48.4177.800000111.1L312 V386 F396 V456 F457 Q462 K463 L464L312-A460 HydrophobicContact CD1-CB 4.31Å; V386-A460 HydrophobicContact CG1-CB 3.83Å; V386-A460 HydrophobicContact CG2-CB 4.22Å; F396-A460 HydrophobicContact CD1-CB 3.98Å; F396-A460 HydrophobicContact CE1-CB 3.53Å; F396-A460 HydrophobicContact CE2-CB 4.14Å; F396-A460 HydrophobicContact CG-CB 4.48Å; F396-A460 HydrophobicContact CZ-CB 3.62Å; V456-A460 PolarHBondContact O-N 3.11Å; F457-A460 PolarHBondContact O-N 3.4Å; A460-Q462 VanDerWaalsContact C-N 3.3Å; A460-Q462 PolarHBondContact O-N 3.49Å; A460-K463 WeakPolarHBondContact O-CB 3.35Å; A460-K463 PolarHBondContact O-N 3.46Å; A460-K463 VanDerWaalsContact O-N 3.12Å; A460-L464 WeakPolarHBondContact O-CG 3.3Å; A460-L464 PolarHBondContact O-N 3.21Å
461L94.6Very high86Confident31 Ų3174.7 Ų74.716%0.16237%0.373CS..Hα-helixtrans-58.3-40.1178-174.465.3000112.6L312 F457 L458 K459 K465L312-L461 HydrophobicContact CD1-CB 4.24Å; L312-L461 HydrophobicContact CD1-CD1 4.31Å; F457-L461 HydrophobicContact CE1-CD2 4.38Å; F457-L461 WeakPolarHBondContact O-CB 3.48Å; F457-L461 PolarHBondContact O-N 2.97Å; L458-L461 PolarHBondContact O-N 3.35Å; K459-L461 PolarHBondContact O-N 3.24Å; L461-K465 HydrophobicContact CG-CD 4.48Å; L461-K465 WeakPolarHBondContact O-CG 3.24Å; L461-K465 PolarHBondContact O-N 3.45Å; L461-K465 VanDerWaalsContact O-N 3.11Å
462Q94.3Very high83.5Confident144 Ų14472 Ų7267%0.67337%0.365SS*.Hα-helixtrans-64.9-42.5177-172.5177.77.400111.7L458 K459 A460 K465 A466L458-Q462 WeakPolarHBondContact O-CB 3.46Å; L458-Q462 PolarHBondContact O-N 3.45Å; K459-Q462 PolarHBondContact O-N 3.41Å; A460-Q462 VanDerWaalsContact C-N 3.3Å; A460-Q462 PolarHBondContact O-N 3.49Å; Q462-K465 PolarHBondContact O-N 3.04Å; Q462-A466 PolarHBondContact O-N 3.41Å
463K94.4Very high80.7Confident58 Ų5877.1 Ų77.125%0.25238%0.381SS..Hα-helixtrans-62.9-44.7176.6-73.4-173.7164.3-149.90112.2E385 V386 D387 K459 A460 K465 A466 G467E385-K463 IonicContact OE2-NZ 2.67Å; E385-K463 PolarHBondContact OE2-NZ 3.23Å; V386-K463 HydrophobicContact CG2-CB 3.67Å; V386-K463 HydrophobicContact CG2-CD 4.26Å; D387-K463 VanDerWaalsContact CG-NZ 3.29Å; D387-K463 IonicContact OD1-NZ 2.67Å; D387-K463 PolarHBondContact OD1-NZ 2.98Å; D387-K463 IonicContact OD2-NZ 3.76Å; D387-K463 PolarHBondContact OD2-NZ 2.61Å; K459-K463 WeakPolarHBondContact O-CG 3.48Å; K459-K463 PolarHBondContact O-N 2.99Å; K459-K463 VanDerWaalsContact O-N 3.07Å; A460-K463 WeakPolarHBondContact O-CB 3.35Å; A460-K463 PolarHBondContact O-N 3.46Å; A460-K463 VanDerWaalsContact O-N 3.12Å; K463-K465 VanDerWaalsContact C-N 3.34Å; K463-K465 PolarHBondContact O-N 3.46Å; K463-A466 PolarHBondContact O-N 3.45Å; K463-G467 PolarHBondContact O-N 3.16Å
464L90.9Very high77.9Confident26 Ų2687.5 Ų87.514%0.13642%0.419CS..Hα-helixtrans-60.7-42.9177.2-65.7174.7000111.9L312 V386 P393 A460 G467 R468L312-L464 HydrophobicContact CD1-CD1 3.69Å; L312-L464 HydrophobicContact CD2-CD1 3.89Å; L312-L464 HydrophobicContact CG-CD1 3.61Å; V386-L464 HydrophobicContact CB-CD2 4.26Å; V386-L464 HydrophobicContact CG2-CD2 3.91Å; V386-L464 HydrophobicContact CG2-CG 3.98Å; P393-L464 HydrophobicContact CB-CD2 3.69Å; P393-L464 HydrophobicContact CG-CD2 3.9Å; A460-L464 WeakPolarHBondContact O-CG 3.3Å; A460-L464 PolarHBondContact O-N 3.21Å; L464-G467 PolarHBondContact O-N 3.17Å; L464-R468 WeakPolarHBondContact O-CG 3.48Å; L464-R468 PolarHBondContact O-N 3.26Å
465K88.2Confident75Confident99 Ų9987.1 Ų87.143%0.4344%0.439SS..Hα-helixtrans-61.2-46.3175.3-73.8173.5-178.41750111.5L461 Q462 K463 G467 R468 F469L461-K465 HydrophobicContact CG-CD 4.48Å; L461-K465 WeakPolarHBondContact O-CG 3.24Å; L461-K465 PolarHBondContact O-N 3.45Å; L461-K465 VanDerWaalsContact O-N 3.11Å; Q462-K465 PolarHBondContact O-N 3.04Å; K463-K465 VanDerWaalsContact C-N 3.34Å; K463-K465 PolarHBondContact O-N 3.46Å; K465-G467 PolarHBondContact O-N 3.13Å; K465-R468 PolarHBondContact O-N 2.7Å; K465-F469 WeakPolarHBondContact O-CD2 3.15Å; K465-F469 PolarHBondContact O-N 3.42Å
466A85.4Confident72Confident53 Ų5385 Ų8544%0.43844%0.443SS..Hα-helixtrans-61.1-41.5178.900000112.7Q462 K463 R468 F469 H470Q462-A466 PolarHBondContact O-N 3.41Å; K463-A466 PolarHBondContact O-N 3.45Å; A466-R468 PolarHBondContact O-N 3.4Å; A466-F469 PolarHBondContact O-N 3.42Å; A466-H470 PolarHBondContact O-N 3.34Å
467G75.2Confident69Low43 Ų4392.9 Ų92.944%0.44348%0.479SS..Hα-helixtrans-60.5-41177.200000113.5K463 L464 K465 F469 H470 S471K463-G467 PolarHBondContact O-N 3.16Å; L464-G467 PolarHBondContact O-N 3.17Å; K465-G467 PolarHBondContact O-N 3.13Å; G467-F469 VanDerWaalsContact C-N 3.3Å; G467-F469 PolarHBondContact O-N 3.35Å; G467-H470 PolarHBondContact O-N 3.44Å; G467-H470 VanDerWaalsContact O-N 3.13Å; G467-S471 PolarHBondContact O-N 3.34Å; G467-S471 VanDerWaalsContact O-N 3.17Å; G467-S471 PolarHBondContact O-OG 3.3Å
468R66.3Low66Low118 Ų118100.6 Ų100.645%0.44552%0.52SS..Hα-helixtrans-63.5-31.8177.5-68.3-179-168-153.73.6113.4D309 G310 L464 K465 A466 H470 S471 S472D309-R468 PolarHBondContact O-NH2 2.97Å; G310-R468 PolarHBondContact O-NH2 3Å; L464-R468 WeakPolarHBondContact O-CG 3.48Å; L464-R468 PolarHBondContact O-N 3.26Å; K465-R468 PolarHBondContact O-N 2.7Å; A466-R468 PolarHBondContact O-N 3.4Å; R468-H470 VanDerWaalsContact C-N 3.33Å; R468-S471 PolarHBondContact O-OG 3.49Å; R468-S472 PolarHBondContact O-N 3.38Å; R468-S472 PolarHBondContact O-OG 3.3Å
469F56.6Low62.9Low145 Ų145105 Ų10564%0.63654%0.538SS*.Hα-helixtrans-74.4-22.3176.5-74.5-70.6000113.2K465 A466 G467 S472K465-F469 WeakPolarHBondContact O-CD2 3.15Å; K465-F469 PolarHBondContact O-N 3.42Å; A466-F469 PolarHBondContact O-N 3.42Å; G467-F469 VanDerWaalsContact C-N 3.3Å; G467-F469 PolarHBondContact O-N 3.35Å; F469-S472 WeakPolarHBondContact CA-OG 3.47Å; F469-S472 PolarHBondContact O-OG 2.82Å
470H48.2Very low60Low137 Ų137107.4 Ų107.463%0.63456%0.56SS**Hα-helixtrans-87.4-35.9178.4-80.824.9000112.6A466 G467 R468 R473 R474A466-H470 PolarHBondContact O-N 3.34Å; G467-H470 PolarHBondContact O-N 3.44Å; G467-H470 VanDerWaalsContact O-N 3.13Å; R468-H470 VanDerWaalsContact C-N 3.33Å; H470-R473 PolarHBondContact O-N 3.26Å; H470-R474 PolarHBondContact O-N 3.33Å
471S47.4Very low56.8Low81 Ų81113.1 Ų113.157%0.56660%0.601SS**Hα-helixtrans-67-36.8174.155.50000112.6G467 R468 R473 R474 G475G467-S471 PolarHBondContact O-N 3.34Å; G467-S471 VanDerWaalsContact O-N 3.17Å; G467-S471 PolarHBondContact O-OG 3.3Å; R468-S471 PolarHBondContact O-OG 3.49Å; S471-R473 VanDerWaalsContact C-N 3.28Å; S471-R473 PolarHBondContact O-N 3.24Å; S471-R474 PolarHBondContact O-N 3.39Å; S471-G475 PolarHBondContact O-N 2.83Å
472S43.1Very low53.7Low78 Ų78123.1 Ų123.155%0.54564%0.636SS.*Hα-helixtrans-68.7-18.7175.541.40000114.6R468 F469R468-S472 PolarHBondContact O-N 3.38Å; R468-S472 PolarHBondContact O-OG 3.3Å; F469-S472 WeakPolarHBondContact CA-OG 3.47Å; F469-S472 PolarHBondContact O-OG 2.82Å
473R38.3Very low50.8Low208 Ų208122.3 Ų122.379%0.78564%0.643SS**Hα-helixtrans-87.7-24.2173.1-75.4-175.5178.5-171.2-0.1113.9H470 S471H470-R473 PolarHBondContact O-N 3.26Å; S471-R473 VanDerWaalsContact C-N 3.28Å; S471-R473 PolarHBondContact O-N 3.24Å
474R37.3Very low47.6Very low233 Ų233125.5 Ų125.588%0.87967%0.668SS**Hα-helixtrans-85.6-17.8178.4-78-173.8175.7-165.8-0.5113.9H470 S471H470-R474 PolarHBondContact O-N 3.33Å; S471-R474 PolarHBondContact O-N 3.39Å
475G33.6Very low44.6Very low69 Ų69130.4 Ų130.471%0.71170%0.701SS**SBendtrans-84.33.1178.400000116S471S471-G475 PolarHBondContact O-N 2.83Å
476A33.7Very low41.7Very low83 Ų83133.7 Ų133.769%0.68672%0.723SS**  trans-98.213.7-169.700000115.6
477E35.3Very low38.9Very low183 Ų183135.9 Ų135.986%0.85574%0.735SS**SBendtrans-113.317.6-176.8-83.2-171.7170.500116.3
478L34.3Very low36.7Very low166 Ų166145.4 Ų145.487%0.86976%0.757SS**SBendtrans-130.1102.5172-72168.5000113.1
479Q30.8Very low34.9Very low181 Ų181146.8 Ų146.885%0.84677%0.773SS**  trans71.9140.5157.8-64.7-94.74.700119.8
480P34.5Very low33.7Very low119 Ų119144.8 Ų144.877%0.77378%0.778SS**  trans-97.7125.9-174.235.7-27.3000112.6
481S31.5Very low33.1Very low121 Ų121144.3 Ų144.385%0.84679%0.787SS**  trans-134.6135.516453.20000112
482R29.2Very low32.7Very low240 Ų240149.3 Ų149.391%0.90679%0.793SS**  trans-49.7150.3-172.8-94.3173.2162173.4-5.7115.2
483P31.9Very low32.1Very low127 Ų127149.6 Ų149.683%0.82580%0.795SS**  trans-79133-178.932.3-31.9000111.9
484T27.6Very low32.1Very low125 Ų125145.9 Ų145.977%0.76779%0.79SS**  trans-105.7142.7157.3-100000107.3L486T484-L486 PolarHBondContact O-N 3.07Å; T484-L486 VanDerWaalsContact O-N 3.15Å
485P27.5Very low31.9Very low129 Ų129142.4 Ų142.484%0.83878%0.783SS**  trans-77.6110.1-166.921.9-15.2000110.7
486L28Very low31.7Very low169 Ų169145.3 Ų145.389%0.88579%0.787SS**  trans-68.6127.3163.9-80.1157.3000108.9T484 R488T484-L486 PolarHBondContact O-N 3.07Å; T484-L486 VanDerWaalsContact O-N 3.15Å; L486-R488 PolarHBondContact O-N 3.48Å
487S26.9Very low31.9Very low98 Ų98146.9 Ų146.969%0.68579%0.791SS**  trans-46.9125.8166.9-1780000110D489S487-D489 PolarHBondContact O-N 3.5Å
488R28.5Very low31.6Very low243 Ų243142.6 Ų142.692%0.91778%0.781SS**  trans-67.795.4165.2-91.7176.2157.4177.9-5.5107.9L486L486-R488 PolarHBondContact O-N 3.48Å
489D29Very low31.4Very low147 Ų147141.8 Ų141.879%0.78678%0.777SS**  trans-114.1128.1152.9-84.3-45.3000109.1S487S487-D489 PolarHBondContact O-N 3.5Å
490S30.4Very low31.5Very low104 Ų104141.6 Ų141.673%0.72777%0.768SS**  trans-59.5152-157-52.80000116R492S490-R492 PolarHBondContact O-N 3.2Å
491P35.8Very low31.5Very low127 Ų127142.3 Ų142.383%0.82577%0.773SS**  trans-67.9117.4165.926.9-28.3000109.2S493P491-S493 VanDerWaalsContact C-N 3.26Å; P491-S493 PolarHBondContact O-N 2.92Å
492R38.6Very low31.9Very low186 Ų186139.7 Ų139.770%0.70276%0.755SS**  trans-63.388.5169.1-75.4179.3176.3-177.3-3.5108.7E413 S490 L494E413-R492 IonicContact OE2-NH2 3.17Å; E413-R492 PolarHBondContact OE2-NH2 3.2Å; S490-R492 PolarHBondContact O-N 3.2Å; R492-L494 PolarHBondContact O-N 2.96Å
493S32Very low32.9Very low83 Ų83133.3 Ų133.358%0.5874%0.739SS**  trans-68116.8169.6175.20000109.2P491 H495P491-S493 VanDerWaalsContact C-N 3.26Å; P491-S493 PolarHBondContact O-N 2.92Å; S493-H495 VanDerWaalsContact C-N 3.3Å; S493-H495 PolarHBondContact O-N 3.48Å
494L38.6Very low34.2Very low130 Ų130132.1 Ų132.168%0.68173%0.729SS**  trans-68.990.2165.1-80.6156000108R492 T496R492-L494 PolarHBondContact O-N 2.96Å; L494-T496 PolarHBondContact O-N 2.71Å
495H32.1Very low36.2Very low160 Ų160130.3 Ų130.374%0.74172%0.718SS**  trans-62.4128.5164.1-81.3-74.1000109.2S493S493-H495 VanDerWaalsContact C-N 3.3Å; S493-H495 PolarHBondContact O-N 3.48Å
496T29.8Very low38.9Very low130 Ų130127.1 Ų127.180%0.79869%0.692SS**  trans-44.7127.5163.7-25.10000109.1L494 S498L494-T496 PolarHBondContact O-N 2.71Å; T496-S498 PolarHBondContact O-N 3.28Å
497P38.5Very low41.8Very low116 Ų116119.2 Ų119.275%0.75365%0.65SS**  trans-70.3109.9-179.626-28.9000108.5L499P497-L499 PolarHBondContact O-N 3.02Å
498S28.6Very low44.9Very low94 Ų94116.8 Ų116.866%0.65763%0.633SS**  trans-72.1109.3151.761.20000106.1T496 R500T496-S498 PolarHBondContact O-N 3.28Å; S498-R500 PolarHBondContact O-N 2.94Å
499L29.6Very low48Very low149 Ų149105.9 Ų105.978%0.7859%0.593SS**  trans-52.7104.1165.9-86147.1000107P497P497-L499 PolarHBondContact O-N 3.02Å
500R33.9Very low51.2Low176 Ų176105.2 Ų105.266%0.66458%0.583SS**  trans-75.5142.2169.2-68.4-169.8-176.1-1692.5106.4S498 S502 D503S498-R500 PolarHBondContact O-N 2.94Å; R500-S502 WeakPolarHBondContact CB-OG 3.27Å; R500-S502 PolarHBondContact O-N 3.46Å; R500-D503 PolarHBondContact O-N 3.01Å
501P33.2Very low54.3Low134 Ų134100.7 Ų100.787%0.8755%0.55SS**THydrogen-bonded Turntrans-59.34.7176.6-23.532.9000115.9
502S40.5Very low57.1Low67 Ų67100.6 Ų100.647%0.46954%0.537SS..THydrogen-bonded Turntrans-97-6.2-175.646.70000115R500 V504R500-S502 WeakPolarHBondContact CB-OG 3.27Å; R500-S502 PolarHBondContact O-N 3.46Å; S502-V504 PolarHBondContact O-N 3.49Å
503D49.7Very low59.7Low105 Ų10593.8 Ų93.856%0.56151%0.514SS*.  trans-77.221.8-177.1-60.1-24.7000114R500 V505R500-D503 PolarHBondContact O-N 3.01Å; D503-V505 PolarHBondContact O-N 3.11Å; D503-V505 VanDerWaalsContact O-N 3.11Å
504V59.6Low62.7Low102 Ų10294.5 Ų94.562%0.61851%0.511SS*.  trans-76.6103.3178-1760000108.4S502 Q506S502-V504 PolarHBondContact O-N 3.49Å; V504-Q506 WeakPolarHBondContact O-CG 3.19Å; V504-Q506 PolarHBondContact O-N 2.97Å
505V68.8Low65.2Low88 Ų8893.2 Ų93.253%0.53351%0.505SS..  trans-49.8113.9172.4-177.90000109.3D503 V507 M532D503-V505 PolarHBondContact O-N 3.11Å; D503-V505 VanDerWaalsContact O-N 3.11Å; V505-V507 VanDerWaalsContact CG1-O 3.24Å; V505-V507 WeakPolarHBondContact CG1-O 3.13Å; V505-M532 HydrophobicContact CB-CE 3.78Å; V505-M532 HydrophobicContact CG1-CE 3.51Å; V505-M532 WeakPolarHBondContact O-CE 3.21Å
506Q84.3Confident68Low62 Ų6289.8 Ų89.829%0.2950%0.497SS..  trans-90.3-25.3-173.2-54.9-166.717.600112.6V504 N531 M532 S533V504-Q506 WeakPolarHBondContact O-CG 3.19Å; V504-Q506 PolarHBondContact O-N 2.97Å; Q506-N531 PolarHBondContact O-OD1 2.87Å; Q506-M532 PolarHBondContact O-N 2.88Å; Q506-S533 PolarHBondContact O-N 2.84Å
507V89.3Confident70.9Confident2 Ų284.7 Ų84.71%0.01247%0.466CS..EExtended strand (participates in β ladder)trans-136.1136.8179.6170.10000108.9V505 L509 L530 K537 L539 I609V505-V507 VanDerWaalsContact CG1-O 3.24Å; V505-V507 WeakPolarHBondContact CG1-O 3.13Å; V507-L509 HydrophobicContact CG1-CD2 4.27Å; V507-L530 CarbonylContact C-O 3.53Å; V507-L530 WeakPolarHBondContact CA-O 3.41Å; V507-K537 HydrophobicContact CG2-CB 4.21Å; V507-K537 HydrophobicContact CG2-CD 4.12Å; V507-K537 HydrophobicContact CG2-CG 3.83Å; V507-L539 HydrophobicContact CG1-CD1 3.59Å; V507-L539 HydrophobicContact CG1-CD2 4.3Å; V507-L539 HydrophobicContact CG2-CD1 4.25Å; V507-L539 HydrophobicContact CG2-CD2 4.3Å; V507-I609 HydrophobicContact CB-CD1 3.6Å; V507-I609 HydrophobicContact CG1-CD1 3.87Å
508S91.8Very high73.3Confident48 Ų4881.9 Ų81.934%0.33645%0.445SS..EExtended strand (participates in β ladder)trans-110.2133173.3-179.20000110.1A529 L530S508-A529 WeakPolarHBondContact O-CA 3.28Å; S508-L530 PolarHBondContact N-O 2.92Å; S508-L530 PolarHBondContact O-N 3.09Å
509L94.2Very high76.1Confident13 Ų1377.8 Ų77.87%0.06842%0.415CS..EExtended strand (participates in β ladder)trans-115.3137.8173.2-63-177.7000109.7V507 L527 L528 A529 V541 I609 V611V507-L509 HydrophobicContact CG1-CD2 4.27Å; L509-L527 HydrophobicContact CB-CD1 4.22Å; L509-L528 CarbonylContact C-O 3.6Å; L509-L528 WeakPolarHBondContact CA-O 3.41Å; L509-A529 HydrophobicContact CD2-CB 3.64Å; L509-V541 HydrophobicContact CD1-CG1 4.38Å; L509-V541 HydrophobicContact CD1-CG2 4.46Å; L509-I609 HydrophobicContact CB-CG2 4.39Å; L509-I609 HydrophobicContact CD1-CB 4.27Å; L509-I609 HydrophobicContact CD1-CG2 3.96Å; L509-I609 HydrophobicContact CG-CG2 4.05Å; L509-V611 HydrophobicContact CB-CB 4.21Å; L509-V611 HydrophobicContact CB-CG1 3.62Å; L509-V611 HydrophobicContact CD1-CG1 4.48Å
510K95Very high79Confident134 Ų13471.3 Ų71.358%0.58338%0.384SS*.EExtended strand (participates in β ladder)trans-148.5134.2178.5-175.3173.2-178.2173.40112.2L528K510-L528 HydrophobicContact CB-CB 4.4Å; K510-L528 PolarHBondContact N-O 2.98Å; K510-L528 WeakPolarHBondContact O-CB 3.39Å; K510-L528 PolarHBondContact O-N 2.78Å
511F95.8Very high81.7Confident9 Ų968 Ų684%0.03938%0.376CS..EExtended strand (participates in β ladder)trans-84.8138170.2-68.3-61.5000112.2F525 V526 L527 L543 I596 A598 V611 K613F511-F525 AromaticContact CD1-CD2 3.9Å; F511-F525 HydrophobicContact CD1-CD2 3.9Å; F511-F525 AromaticContact CD1-CE2 3.91Å; F511-F525 HydrophobicContact CD1-CE2 3.91Å; F511-F525 HydrophobicContact CE1-CD2 4.3Å; F511-F525 AromaticContact CE1-CE2 3.84Å; F511-F525 HydrophobicContact CE1-CE2 3.84Å; F511-V526 WeakPolarHBondContact CA-O 3.29Å; F511-L527 HydrophobicContact CD1-CB 4.36Å; F511-L527 HydrophobicContact CD1-CD1 4.02Å; F511-L527 HydrophobicContact CE1-CB 4.24Å; F511-L527 HydrophobicContact CE1-CD1 3.8Å; F511-L527 HydrophobicContact CZ-CD1 4.3Å; F511-L543 HydrophobicContact CE1-CD2 3.66Å; F511-L543 HydrophobicContact CZ-CD2 3.75Å; F511-I596 HydrophobicContact CB-CD1 3.9Å; F511-I596 HydrophobicContact CD1-CD1 3.67Å; F511-I596 HydrophobicContact CD2-CD1 3.77Å; F511-I596 HydrophobicContact CD2-CG1 3.92Å; F511-I596 HydrophobicContact CE1-CD1 4.05Å; F511-I596 HydrophobicContact CE2-CB 4.43Å; F511-I596 HydrophobicContact CE2-CD1 4.13Å; F511-I596 HydrophobicContact CE2-CG1 4.01Å; F511-I596 HydrophobicContact CG-CD1 3.51Å; F511-I596 HydrophobicContact CG-CG1 4.2Å; F511-I596 HydrophobicContact CZ-CB 4.46Å; F511-I596 HydrophobicContact CZ-CD1 4.24Å; F511-I596 HydrophobicContact CZ-CG1 4.37Å; F511-A598 HydrophobicContact CE1-CB 4.27Å; F511-A598 HydrophobicContact CE2-CB 4.06Å; F511-A598 HydrophobicContact CZ-CB 3.48Å; F511-A598 VanDerWaalsContact CZ-CB 3.48Å; F511-V611 HydrophobicContact CD2-CG1 4.22Å; F511-V611 HydrophobicContact CD2-CG2 4.32Å; F511-V611 HydrophobicContact CE2-CG1 3.9Å; F511-V611 HydrophobicContact CZ-CG1 4.43Å; F511-K613 HydrophobicContact CB-CB 4.12Å; F511-K613 HydrophobicContact CB-CD 3.94Å; F511-K613 HydrophobicContact CD2-CB 4Å; F511-K613 HydrophobicContact CG-CB 4.47Å
512K94.8Very high84.7Confident124 Ų12464.9 Ų64.954%0.53935%0.352SS..EExtended strand (participates in β ladder)trans-133.5124.4171.5-177.6-178.1177.5-174.40110F525 V526 L528K512-F525 CarbonylContact O-C 3.57Å; K512-F525 WeakPolarHBondContact O-CA 3.17Å; K512-F525 WeakPolarHBondContact O-CB 3.48Å; K512-V526 HydrophobicContact CB-CG2 3.88Å; K512-V526 PolarHBondContact N-O 3.03Å; K512-V526 PolarHBondContact O-N 3.22Å; K512-L528 HydrophobicContact CB-CD1 4.2Å; K512-L528 HydrophobicContact CD-CD1 4.49Å
513L94.3Very high87.3Confident44 Ų4461.9 Ų61.923%0.2333%0.331CS..EExtended strand (participates in β ladder)trans-70140.9171-63.8179.3000109.5P517 I523 F525 I615L513-P517 HydrophobicContact CD1-CG 4.14Å; L513-I523 HydrophobicContact CD2-CG2 4.33Å; L513-F525 HydrophobicContact CD2-CB 3.84Å; L513-I615 HydrophobicContact CD2-CD1 3.8Å; L513-I615 HydrophobicContact CD2-CG1 4.16Å
514L94.7Very high89.5Confident97 Ų9758.6 Ų58.651%0.50832%0.316SS..SBendtrans-84.6-37.2175.7-66.4178000111.4C524 V526L514-C524 HydrophobicContact CB-CB 4.23Å; L514-C524 HydrophobicContact CD1-CB 4.17Å; L514-C524 PolarHBondContact N-O 2.78Å; L514-V526 HydrophobicContact CD1-CG1 4.08Å; L514-V526 HydrophobicContact CD2-CG1 3.87Å; L514-V526 HydrophobicContact CD2-CG2 4.43Å; L514-V526 HydrophobicContact CG-CG1 4.16Å
515D91.5Very high91.3Very high104 Ų10453.7 Ų53.756%0.55629%0.286SS*.SBendtrans-135.3161-178.6-61.2-71.4000110.9
516P89.8Confident92.7Very high88 Ų8850.3 Ų50.357%0.57127%0.265SS*.  trans-57.1132.5169.5-2434.6000111.4N518P516-N518 PolarHBondContact O-N 3.26Å
517P90.3Very high93.3Very high23 Ų2347.3 Ų47.315%0.14925%0.252CS..  trans-80.484.3-17634.2-36.8000110.5L513 I615 T616 L617 S618L513-P517 HydrophobicContact CD1-CG 4.14Å; P517-I615 HydrophobicContact CB-CG2 3.58Å; P517-I615 HydrophobicContact CG-CG2 3.73Å; P517-T616 VanDerWaalsContact CG-O 3.31Å; P517-T616 WeakPolarHBondContact CG-O 3.36Å; P517-L617 HydrophobicContact CB-CD2 4Å; P517-L617 CarbonylContact O-C 3.6Å; P517-L617 VanDerWaalsContact O-CA 3.32Å; P517-L617 WeakPolarHBondContact O-CA 3.49Å; P517-S618 PolarHBondContact O-N 2.72Å
518N90Very high93.7Very high57 Ų5749.9 Ų49.931%0.30527%0.265SS..BIsolated β-bridgetrans-83.8138.7178.9-58.2-50.2000111.6P516 G520 Q521P516-N518 PolarHBondContact O-N 3.26Å; N518-G520 PolarHBondContact O-N 2.95Å; N518-Q521 HydrophobicContact CB-CG 4.27Å; N518-Q521 PolarHBondContact ND2-OE1 3.09Å; N518-Q521 VanDerWaalsContact ND2-OE1 3.08Å; N518-Q521 PolarHBondContact O-N 2.64Å; N518-Q521 VanDerWaalsContact O-N 3.14Å
519M88.1Confident93.9Very high8 Ų847.7 Ų47.74%0.03925%0.249CC..THydrogen-bonded Turntrans-58.5132.5174.5-178.762.9172.400110.8Y581 Y584 L588 L617 S618 Y619 L646M519-Y581 HydrophobicContact CE-CE2 3.97Å; M519-Y581 HydrophobicContact SD-CE2 4.23Å; M519-Y584 HydrophobicContact SD-CE2 4.25Å; M519-L588 HydrophobicContact CE-CD1 3.66Å; M519-L588 HydrophobicContact SD-CD1 3.59Å; M519-L588 VanDerWaalsContact SD-CD1 3.59Å; M519-L617 HydrophobicContact SD-CD1 3.76Å; M519-S618 WeakPolarHBondContact CB-O 3.08Å; M519-S618 PolarHBondContact N-O 3.42Å; M519-Y619 HydrophobicContact CB-CD1 4.18Å; M519-Y619 HydrophobicContact CB-CD2 4.23Å; M519-Y619 HydrophobicContact CB-CE1 3.95Å; M519-Y619 HydrophobicContact CB-CE2 3.95Å; M519-Y619 HydrophobicContact CB-CG 4.33Å; M519-Y619 WeakPolarHBondContact CE-OH 3.43Å; M519-Y619 HydrophobicContact CG-CD1 4.21Å; M519-Y619 HydrophobicContact CG-CE1 3.56Å; M519-Y619 HydrophobicContact CG-CE2 4.15Å; M519-Y619 HydrophobicContact SD-CE1 4.46Å; M519-Y619 PolarHBondContact SD-OH 3.3Å; M519-L646 HydrophobicContact CE-CD2 4.43Å; M519-L646 HydrophobicContact CG-CD2 4.05Å
520G89.1Confident93.9Very high12 Ų1250.3 Ų50.312%0.12426%0.263CS..THydrogen-bonded Turntrans91.5-7.4-177.900000114.4N518 Y581 Y584N518-G520 PolarHBondContact O-N 2.95Å; G520-Y581 VanDerWaalsContact CA-CD2 3.45Å; G520-Y584 PolarHBondContact N-OH 2.91Å
521Q92.3Very high93.9Very high108 Ų10844 Ų4451%0.50524%0.236SC..SBendtrans-108.6160.5178.2-62-174.7-19.200111.8N518 Y584N518-Q521 HydrophobicContact CB-CG 4.27Å; N518-Q521 PolarHBondContact ND2-OE1 3.09Å; N518-Q521 VanDerWaalsContact ND2-OE1 3.08Å; N518-Q521 PolarHBondContact O-N 2.64Å; N518-Q521 VanDerWaalsContact O-N 3.14Å; Q521-Y584 VanDerWaalsContact O-CE1 3.32Å; Q521-Y584 WeakPolarHBondContact O-CE1 3.4Å; Q521-Y584 PolarHBondContact O-OH 3.32Å
522D95.1Very high93.7Very high67 Ų6747.1 Ų47.136%0.35825%0.251SS..  trans-69.8141.4173.8-61.9-22.3000110.5K578 S580 Y581D522-K578 HydrophobicContact CB-CG 4.48Å; D522-K578 VanDerWaalsContact CG-CE 3.41Å; D522-K578 WeakPolarHBondContact OD2-CE 3.3Å; D522-K578 IonicContact OD2-NZ 2.73Å; D522-K578 PolarHBondContact OD2-NZ 2.9Å; D522-S580 WeakPolarHBondContact OD1-CA 3.4Å; D522-S580 WeakPolarHBondContact OD1-CB 3.13Å; D522-Y581 PolarHBondContact OD1-N 3.07Å
523I95.6Very high93.4Very high4 Ų442 Ų422%0.02123%0.231CC..EExtended strand (participates in β ladder)trans-91.2109.8175.8-55.8169000108.1L513 F525 K578 I579 Y584 I594 I615 L617L513-I523 HydrophobicContact CD2-CG2 4.33Å; I523-F525 HydrophobicContact CG2-CD1 4.18Å; I523-K578 WeakPolarHBondContact O-CA 3.33Å; I523-I579 HydrophobicContact CB-CB 4.35Å; I523-I579 PolarHBondContact N-O 2.95Å; I523-I579 PolarHBondContact O-N 3.03Å; I523-Y584 HydrophobicContact CD1-CD1 3.85Å; I523-Y584 HydrophobicContact CD1-CE1 3.77Å; I523-Y584 HydrophobicContact CD1-CG 4.47Å; I523-Y584 HydrophobicContact CG1-CD1 4.26Å; I523-Y584 HydrophobicContact CG1-CE1 3.76Å; I523-I594 HydrophobicContact CD1-CD1 3.57Å; I523-I615 HydrophobicContact CG2-CD1 3.93Å; I523-L617 HydrophobicContact CD1-CD2 3.99Å; I523-L617 HydrophobicContact CG1-CD2 4.4Å
524C96.4Very high93.2Very high36 Ų3644.7 Ų44.724%0.24325%0.254CS..EExtended strand (participates in β ladder)trans-104.8125.1178.9-64.80000110.5L514L514-C524 HydrophobicContact CB-CB 4.23Å; L514-C524 HydrophobicContact CD1-CB 4.17Å; L514-C524 PolarHBondContact N-O 2.78Å
525F96.3Very high93.1Very high0 Ų046 Ų460%026%0.258CS..EExtended strand (participates in β ladder)trans-149.2168.3-178.966.3-83.3000111.8F511 K512 L513 I523 W559 C577 I579 I596F511-F525 AromaticContact CD1-CD2 3.9Å; F511-F525 HydrophobicContact CD1-CD2 3.9Å; F511-F525 AromaticContact CD1-CE2 3.91Å; F511-F525 HydrophobicContact CD1-CE2 3.91Å; F511-F525 HydrophobicContact CE1-CD2 4.3Å; F511-F525 AromaticContact CE1-CE2 3.84Å; F511-F525 HydrophobicContact CE1-CE2 3.84Å; K512-F525 CarbonylContact O-C 3.57Å; K512-F525 WeakPolarHBondContact O-CA 3.17Å; K512-F525 WeakPolarHBondContact O-CB 3.48Å; L513-F525 HydrophobicContact CD2-CB 3.84Å; I523-F525 HydrophobicContact CG2-CD1 4.18Å; F525-W559 HydrophobicContact CZ-CH2 4.08Å; F525-W559 HydrophobicContact CZ-CZ3 4.21Å; F525-C577 HydrophobicContact CD1-CB 3.95Å; F525-C577 HydrophobicContact CD2-CB 3.76Å; F525-C577 HydrophobicContact CE1-CB 3.59Å; F525-C577 HydrophobicContact CE2-CB 3.38Å; F525-C577 HydrophobicContact CG-CB 4.03Å; F525-C577 HydrophobicContact CZ-CB 3.3Å; F525-C577 PolarHBondContact N-O 2.95Å; F525-C577 PolarHBondContact O-N 3.49Å; F525-C577 VanDerWaalsContact O-O 3.04Å; F525-I579 HydrophobicContact CE1-CD1 3.76Å; F525-I579 HydrophobicContact CE1-CG1 3.95Å; F525-I579 HydrophobicContact CZ-CD1 4.27Å; F525-I596 HydrophobicContact CD2-CD1 3.8Å; F525-I596 HydrophobicContact CE2-CD1 3.7Å; F525-I596 HydrophobicContact CG-CD1 4.34Å; F525-I596 HydrophobicContact CZ-CD1 4.16Å; F525-I596 HydrophobicContact CZ-CG2 4.21Å
526V97.3Very high93.1Very high16 Ų1646.6 Ų46.610%0.09726%0.255CS..EExtended strand (participates in β ladder)trans-126.7143.2175.6-61.90000110.9F511 K512 L514 L528 Y575F511-V526 WeakPolarHBondContact CA-O 3.29Å; K512-V526 HydrophobicContact CB-CG2 3.88Å; K512-V526 PolarHBondContact N-O 3.03Å; K512-V526 PolarHBondContact O-N 3.22Å; L514-V526 HydrophobicContact CD1-CG1 4.08Å; L514-V526 HydrophobicContact CD2-CG1 3.87Å; L514-V526 HydrophobicContact CD2-CG2 4.43Å; L514-V526 HydrophobicContact CG-CG1 4.16Å; V526-L528 HydrophobicContact CG2-CD2 3.75Å; V526-L528 HydrophobicContact CG2-CG 4.24Å; V526-Y575 CarbonylContact C-O 3.59Å; V526-Y575 WeakPolarHBondContact CA-O 3.4Å
527L97.7Very high93.2Very high0 Ų042.5 Ų42.50%023%0.228CC..EExtended strand (participates in β ladder)trans-90.2115161.7177.571000108.5L509 F511 V541 L543 I565 T574 Y575 A598 V611L509-L527 HydrophobicContact CB-CD1 4.22Å; F511-L527 HydrophobicContact CD1-CB 4.36Å; F511-L527 HydrophobicContact CD1-CD1 4.02Å; F511-L527 HydrophobicContact CE1-CB 4.24Å; F511-L527 HydrophobicContact CE1-CD1 3.8Å; F511-L527 HydrophobicContact CZ-CD1 4.3Å; L527-V541 HydrophobicContact CD2-CB 4.3Å; L527-V541 HydrophobicContact CD2-CG1 3.8Å; L527-V541 HydrophobicContact CD2-CG2 4.37Å; L527-L543 HydrophobicContact CD2-CD2 4.41Å; L527-I565 HydrophobicContact CD2-CD1 4.18Å; L527-T574 CarbonylContact O-C 3.6Å; L527-T574 WeakPolarHBondContact O-CA 3.17Å; L527-Y575 PolarHBondContact N-O 3.3Å; L527-Y575 PolarHBondContact O-N 3.14Å; L527-A598 HydrophobicContact CD1-CB 4.12Å; L527-V611 HydrophobicContact CD1-CG1 4.25Å
528L97Very high93.4Very high56 Ų5643.1 Ų43.129%0.29323%0.23SC..EExtended strand (participates in β ladder)trans-87.8124.3172.5-53.3176.8000108.3L509 K510 K512 V526 T574L509-L528 CarbonylContact C-O 3.6Å; L509-L528 WeakPolarHBondContact CA-O 3.41Å; K510-L528 HydrophobicContact CB-CB 4.4Å; K510-L528 PolarHBondContact N-O 2.98Å; K510-L528 WeakPolarHBondContact O-CB 3.39Å; K510-L528 PolarHBondContact O-N 2.78Å; K512-L528 HydrophobicContact CB-CD1 4.2Å; K512-L528 HydrophobicContact CD-CD1 4.49Å; V526-L528 HydrophobicContact CG2-CD2 3.75Å; V526-L528 HydrophobicContact CG2-CG 4.24Å; L528-T574 HydrophobicContact CD2-CG2 3.31Å
529A96.3Very high93.6Very high1 Ų140.4 Ų40.41%0.00822%0.216CC..EExtended strand (participates in β ladder)trans-119121.1175.200000109.5S508 L509 I565 L567 A572 K573S508-A529 WeakPolarHBondContact O-CA 3.28Å; L509-A529 HydrophobicContact CD2-CB 3.64Å; A529-I565 HydrophobicContact CB-CD1 4.07Å; A529-I565 HydrophobicContact CB-CG2 4.27Å; A529-L567 HydrophobicContact CB-CD1 4.07Å; A529-A572 CarbonylContact O-C 3.44Å; A529-A572 VanDerWaalsContact O-CA 3.29Å; A529-A572 WeakPolarHBondContact O-CA 3.43Å; A529-K573 PolarHBondContact N-O 2.68Å; A529-K573 PolarHBondContact O-N 2.83Å
530L95.1Very high93.9Very high69 Ų6943.6 Ų43.636%0.36123%0.229SC..EExtended strand (participates in β ladder)trans-119125.1-180172.367.2000109.9V507 S508 M532 A572V507-L530 CarbonylContact C-O 3.53Å; V507-L530 WeakPolarHBondContact CA-O 3.41Å; S508-L530 PolarHBondContact N-O 2.92Å; S508-L530 PolarHBondContact O-N 3.09Å; L530-M532 HydrophobicContact CD2-CG 3.96Å; L530-M532 HydrophobicContact CD2-SD 4.4Å; L530-M532 HydrophobicContact CG-CG 4Å; L530-A572 HydrophobicContact CD1-CB 3.94Å
531N94Very high94.2Very high0 Ų043 Ų430%022%0.224CC..EExtended strand (participates in β ladder)trans-85.4110.7170.6-179.15.7000109.9Q506 S533 Q535 K537 L567 S568 K570 E571Q506-N531 PolarHBondContact O-OD1 2.87Å; N531-S533 VanDerWaalsContact C-N 3.35Å; N531-S533 WeakPolarHBondContact OD1-CB 3.31Å; N531-S533 PolarHBondContact OD1-N 2.86Å; N531-S533 PolarHBondContact OD1-OG 2.72Å; N531-Q535 PolarHBondContact ND2-O 3.05Å; N531-K537 HydrophobicContact CB-CG 4.45Å; N531-K537 WeakPolarHBondContact OD1-CG 3.1Å; N531-L567 HydrophobicContact CB-CB 3.7Å; N531-L567 HydrophobicContact CB-CD1 3.96Å; N531-L567 HydrophobicContact CB-CG 4.42Å; N531-L567 PolarHBondContact ND2-O 3.46Å; N531-S568 PolarHBondContact ND2-O 3.14Å; N531-K570 WeakPolarHBondContact O-CA 3.32Å; N531-K570 PolarHBondContact O-N 3.23Å; N531-E571 PolarHBondContact N-O 3.1Å
532M91.4Very high94.4Very high75 Ų7538.6 Ų38.637%0.36920%0.203SC..  trans-89.5-6.3179.1-60.2-170.5-59.900112.1V505 Q506 L530 K570V505-M532 HydrophobicContact CB-CE 3.78Å; V505-M532 HydrophobicContact CG1-CE 3.51Å; V505-M532 WeakPolarHBondContact O-CE 3.21Å; Q506-M532 PolarHBondContact O-N 2.88Å; L530-M532 HydrophobicContact CD2-CG 3.96Å; L530-M532 HydrophobicContact CD2-SD 4.4Å; L530-M532 HydrophobicContact CG-CG 4Å; M532-K570 PolarHBondContact O-NZ 3.46Å
533S89.8Confident94.4Very high17 Ų1735.5 Ų35.512%0.11919%0.187CC..SBendtrans-86.3168177.882.80000112.8Q506 N531 Q535 K537 K570Q506-S533 PolarHBondContact O-N 2.84Å; N531-S533 VanDerWaalsContact C-N 3.35Å; N531-S533 WeakPolarHBondContact OD1-CB 3.31Å; N531-S533 PolarHBondContact OD1-N 2.86Å; N531-S533 PolarHBondContact OD1-OG 2.72Å; S533-Q535 VanDerWaalsContact C-N 3.3Å; S533-Q535 PolarHBondContact OG-N 2.98Å; S533-Q535 PolarHBondContact OG-O 2.97Å; S533-Q535 VanDerWaalsContact OG-O 3.08Å; S533-K537 VanDerWaalsContact OG-CE 3.26Å; S533-K537 WeakPolarHBondContact OG-CE 3.36Å; S533-K570 PolarHBondContact O-N 3.38Å
534S90.4Very high94.5Very high100 Ų10035.3 Ų35.370%0.69919%0.186SC*.SBendtrans-87.72.9169.253.10000113.1P569S534-P569 WeakPolarHBondContact O-CB 3.48Å; S534-P569 VanDerWaalsContact O-CG 3.24Å; S534-P569 WeakPolarHBondContact O-CG 3.31Å
535Q90.9Very high94.5Very high126 Ų12633.6 Ų33.659%0.58917%0.174SC*.SBendtrans-108.2156-177.5-64.5-177-2.800110.7N531 S533N531-Q535 PolarHBondContact ND2-O 3.05Å; S533-Q535 VanDerWaalsContact C-N 3.3Å; S533-Q535 PolarHBondContact OG-N 2.98Å; S533-Q535 PolarHBondContact OG-O 2.97Å; S533-Q535 VanDerWaalsContact OG-O 3.08Å
536F92.4Very high94.4Very high116 Ų11634 Ų3451%0.50918%0.176SC..  trans-65.2145.8170.6173.7-95000110.8D538 T566 L567F536-D538 HydrophobicContact CE1-CB 3.93Å; F536-D538 HydrophobicContact CZ-CB 4.48Å; F536-T566 HydrophobicContact CE2-CG2 4.47Å; F536-T566 HydrophobicContact CZ-CG2 3.83Å; F536-L567 WeakPolarHBondContact CD2-O 3.46Å
537K92.3Very high94.1Very high2 Ų233.2 Ų33.21%0.00917%0.172CC..EExtended strand (participates in β ladder)trans-129.1136.1179.6-61.6-69.1174.6179.30111V507 N531 S533 T566 L567 E602V507-K537 HydrophobicContact CG2-CB 4.21Å; V507-K537 HydrophobicContact CG2-CD 4.12Å; V507-K537 HydrophobicContact CG2-CG 3.83Å; N531-K537 HydrophobicContact CB-CG 4.45Å; N531-K537 WeakPolarHBondContact OD1-CG 3.1Å; S533-K537 VanDerWaalsContact OG-CE 3.26Å; S533-K537 WeakPolarHBondContact OG-CE 3.36Å; K537-T566 CarbonylContact O-C 3.45Å; K537-T566 WeakPolarHBondContact O-CA 3.42Å; K537-L567 HydrophobicContact CB-CB 4.31Å; K537-L567 PolarHBondContact N-O 3.48Å; K537-L567 PolarHBondContact O-N 3.05Å; K537-E602 HydrophobicContact CD-CG 4.06Å; K537-E602 WeakPolarHBondContact CD-OE1 3.41Å; K537-E602 WeakPolarHBondContact CD-OE2 3.3Å; K537-E602 IonicContact NZ-OE1 2.75Å; K537-E602 PolarHBondContact NZ-OE1 3.34Å; K537-E602 IonicContact NZ-OE2 2.7Å; K537-E602 PolarHBondContact NZ-OE2 2.95Å
538D93.9Very high93.7Very high35 Ų3533.2 Ų33.219%0.18717%0.172CC..EExtended strand (participates in β ladder)trans-123.1109.3174.9-171.1-0.8000108.9F536 K603F536-D538 HydrophobicContact CE1-CB 3.93Å; F536-D538 HydrophobicContact CZ-CB 4.48Å; D538-K603 HydrophobicContact CB-CD 4.35Å; D538-K603 PolarHBondContact O-N 3.06Å; D538-K603 IonicContact OD1-NZ 2.8Å; D538-K603 VanDerWaalsContact OD2-CD 3.3Å; D538-K603 WeakPolarHBondContact OD2-CD 3.43Å; D538-K603 VanDerWaalsContact OD2-CE 3.27Å; D538-K603 WeakPolarHBondContact OD2-CE 3.38Å; D538-K603 IonicContact OD2-NZ 2.71Å; D538-K603 PolarHBondContact OD2-NZ 3.09Å
539L93.5Very high93.2Very high0 Ų031.7 Ų31.70%016%0.163CC..EExtended strand (participates in β ladder)trans-112.2130-170.5-61.9164.2000110.4V507 V541 F564 I565 L567 E601 E602V507-L539 HydrophobicContact CG1-CD1 3.59Å; V507-L539 HydrophobicContact CG1-CD2 4.3Å; V507-L539 HydrophobicContact CG2-CD1 4.25Å; V507-L539 HydrophobicContact CG2-CD2 4.3Å; L539-V541 HydrophobicContact CB-CG2 4.29Å; L539-F564 WeakPolarHBondContact O-CA 3.38Å; L539-I565 HydrophobicContact CB-CB 4.39Å; L539-I565 WeakPolarHBondContact CB-O 3.4Å; L539-I565 PolarHBondContact N-O 3.27Å; L539-I565 PolarHBondContact O-N 2.96Å; L539-L567 HydrophobicContact CD1-CD1 3.62Å; L539-L567 HydrophobicContact CD1-CG 4.47Å; L539-E601 WeakPolarHBondContact CA-O 3.47Å; L539-E602 HydrophobicContact CD2-CB 3.84Å; L539-E602 HydrophobicContact CD2-CG 4.15Å
540K94.6Very high92.5Very high75 Ų7531.7 Ų31.733%0.32616%0.163SC..EExtended strand (participates in β ladder)trans-99.5122.4159.6-179.7-173.9176.5-170.70108N542 T562 F564 G600 E601K540-N542 WeakPolarHBondContact CE-OD1 3.46Å; K540-T562 HydrophobicContact CG-CG2 4.14Å; K540-F564 HydrophobicContact CB-CD1 4.3Å; K540-F564 HydrophobicContact CB-CE1 4.22Å; K540-F564 HydrophobicContact CD-CE1 4.11Å; K540-F564 HydrophobicContact CG-CD1 4.25Å; K540-F564 HydrophobicContact CG-CE1 3.81Å; K540-F564 HydrophobicContact CG-CZ 4.41Å; K540-G600 CarbonylContact O-C 3.6Å; K540-E601 PolarHBondContact N-O 3.46Å; K540-E601 PolarHBondContact O-N 2.87Å
541V95.5Very high91.9Very high0 Ų029.7 Ų29.70%015%0.153CC..EExtended strand (participates in β ladder)trans-117.6117.5179.7-170.50000109.4L509 L527 L539 L543 T562 A563 I565 A598 L599L509-V541 HydrophobicContact CD1-CG1 4.38Å; L509-V541 HydrophobicContact CD1-CG2 4.46Å; L527-V541 HydrophobicContact CD2-CB 4.3Å; L527-V541 HydrophobicContact CD2-CG1 3.8Å; L527-V541 HydrophobicContact CD2-CG2 4.37Å; L539-V541 HydrophobicContact CB-CG2 4.29Å; V541-L543 HydrophobicContact CG1-CG 4.48Å; V541-T562 CarbonylContact O-C 3.58Å; V541-T562 WeakPolarHBondContact O-CA 3.43Å; V541-A563 HydrophobicContact CB-CB 4.37Å; V541-A563 PolarHBondContact N-O 3.24Å; V541-A563 PolarHBondContact O-N 3.44Å; V541-I565 HydrophobicContact CG2-CD1 4.22Å; V541-A598 HydrophobicContact CG1-CB 3.67Å; V541-L599 WeakPolarHBondContact CA-O 3.45Å
542N96.3Very high91.5Very high15 Ų1529.7 Ų29.78%0.0815%0.153CC..EExtended strand (participates in β ladder)trans-91127.2172.1-57.1-47000108.9N320 K540 A598 L599N320-N542 PolarHBondContact O-ND2 3.05Å; K540-N542 WeakPolarHBondContact CE-OD1 3.46Å; N542-A598 CarbonylContact O-C 3.58Å; N542-A598 WeakPolarHBondContact O-CA 3.47Å; N542-L599 PolarHBondContact N-O 2.87Å; N542-L599 PolarHBondContact O-N 3.01Å
543L96.5Very high91.1Very high2 Ų227.6 Ų27.61%0.0115%0.146CC..EExtended strand (participates in β ladder)trans-110.8139.8-176.3-71.4153.3000109.5F511 L527 V541 W559 Q560 D561 A563 Y575 S597 A598F511-L543 HydrophobicContact CE1-CD2 3.66Å; F511-L543 HydrophobicContact CZ-CD2 3.75Å; L527-L543 HydrophobicContact CD2-CD2 4.41Å; V541-L543 HydrophobicContact CG1-CG 4.48Å; L543-W559 HydrophobicContact CB-CH2 3.8Å; L543-W559 HydrophobicContact CB-CZ3 3.7Å; L543-W559 HydrophobicContact CD1-CH2 4.26Å; L543-W559 HydrophobicContact CG-CH2 4.48Å; L543-Q560 VanDerWaalsContact O-CA 3.24Å; L543-Q560 WeakPolarHBondContact O-CA 3.45Å; L543-D561 HydrophobicContact CB-CB 4.09Å; L543-D561 HydrophobicContact CD1-CB 4.11Å; L543-D561 PolarHBondContact N-O 2.78Å; L543-D561 PolarHBondContact O-N 3.13Å; L543-A563 HydrophobicContact CD1-CB 4.4Å; L543-Y575 HydrophobicContact CD1-CD1 4.25Å; L543-Y575 HydrophobicContact CD1-CE1 4.09Å; L543-S597 WeakPolarHBondContact CA-O 3.43Å; L543-A598 HydrophobicContact CD2-CB 3.77Å
544S96.5Very high91.1Very high0 Ų027.9 Ų27.90%015%0.147CC..EExtended strand (participates in β ladder)trans-142.8146177.6-177.80000110.9W559 I596 S597S544-W559 CarbonylContact C-O 3.54Å; S544-W559 WeakPolarHBondContact CA-O 3.28Å; S544-I596 WeakPolarHBondContact O-CA 3.19Å; S544-S597 PolarHBondContact N-O 3.24Å; S544-S597 PolarHBondContact O-N 3.18Å; S544-S597 PolarHBondContact O-OG 3.25Å
545A96.2Very high91Very high0 Ų026 Ų260%013%0.129CC..EExtended strand (participates in β ladder)trans-125.3130.7168.900000110.9P557 F558 W559 I579 I594 R595 I596A545-P557 WeakPolarHBondContact O-CA 3.26Å; A545-F558 HydrophobicContact CB-CE1 4.4Å; A545-F558 HydrophobicContact CB-CE2 3.85Å; A545-F558 HydrophobicContact CB-CZ 3.77Å; A545-F558 PolarHBondContact O-N 3.47Å; A545-F558 VanDerWaalsContact O-N 3.15Å; A545-W559 HydrophobicContact CB-CB 4.04Å; A545-W559 HydrophobicContact CB-CE3 3.92Å; A545-W559 PolarHBondContact N-O 2.96Å; A545-I579 HydrophobicContact CB-CD1 3.83Å; A545-I594 HydrophobicContact CB-CG2 4.24Å; A545-R595 WeakPolarHBondContact CA-O 3.31Å; A545-I596 HydrophobicContact CB-CG2 3.97Å
546Q94.5Very high91Very high9 Ų924.3 Ų24.34%0.04213%0.131CC..EExtended strand (participates in β ladder)trans-132.3138.8177.1-71.2174.6-80.700109P554 L555 P557 R595Q546-P554 HydrophobicContact CB-CB 4.45Å; Q546-L555 WeakPolarHBondContact CG-O 3.46Å; Q546-L555 PolarHBondContact NE2-O 3.09Å; Q546-P557 HydrophobicContact CG-CB 3.91Å; Q546-R595 PolarHBondContact N-O 3.36Å; Q546-R595 PolarHBondContact O-N 2.99Å
547S92.2Very high91Very high0 Ų020.6 Ų20.60%012%0.118CC..EExtended strand (participates in β ladder)trans-71146.4165.4-58.80000109.3L555 F558 Y587 L593S547-L555 PolarHBondContact O-N 2.86Å; S547-F558 WeakPolarHBondContact OG-CE1 3.37Å; S547-Y587 WeakPolarHBondContact CB-O 3.49Å; S547-Y587 PolarHBondContact OG-O 3.37Å; S547-L593 WeakPolarHBondContact CA-O 3.28Å
548L88.6Confident91.1Very high0 Ų021.7 Ų21.70%012%0.123CC..EExtended strand (participates in β ladder)trans-109.1137.4174.5-59.3-175.3000109.9N335 P554 S589 L593 R595 I614N335-L548 WeakPolarHBondContact OD1-CD1 3.44Å; L548-P554 HydrophobicContact CD2-CB 4.06Å; L548-S589 VanDerWaalsContact O-CB 3.26Å; L548-S589 WeakPolarHBondContact O-CB 3.5Å; L548-S589 PolarHBondContact O-OG 2.96Å; L548-L593 HydrophobicContact CB-CB 4.29Å; L548-L593 PolarHBondContact N-O 3.07Å; L548-R595 HydrophobicContact CD1-CB 3.81Å; L548-R595 HydrophobicContact CD2-CB 4.03Å; L548-R595 HydrophobicContact CG-CB 3.87Å; L548-I614 HydrophobicContact CD1-CD1 4.07Å; L548-I614 HydrophobicContact CD1-CG1 4.2Å
549L85.7Confident91.2Very high23 Ų2321.1 Ų21.112%0.1212%0.118CC..  trans-71.4165.9161.3-60.3-174.5000110E244 N335 D551 G552 S553 L555E244-L549 HydrophobicContact CG-CD2 3.43Å; E244-L549 VanDerWaalsContact CG-CD2 3.43Å; N335-L549 PolarHBondContact ND2-O 3.17Å; L549-D551 VanDerWaalsContact C-N 3.28Å; L549-D551 VanDerWaalsContact CB-OD1 3.3Å; L549-D551 WeakPolarHBondContact CB-OD1 3.31Å; L549-D551 PolarHBondContact O-N 3.31Å; L549-G552 PolarHBondContact O-N 3.43Å; L549-S553 PolarHBondContact N-O 2.81Å; L549-L555 HydrophobicContact CD1-CD2 4.28Å; L549-L555 HydrophobicContact CD2-CD1 4.1Å; L549-L555 HydrophobicContact CD2-CD2 3.93Å; L549-L555 HydrophobicContact CD2-CG 4.09Å; L549-L555 HydrophobicContact CG-CD2 4.03Å; L549-L555 HydrophobicContact CG-CG 4.3Å
550H82.4Confident91.3Very high1 Ų125.9 Ų25.91%0.00514%0.141CC..THydrogen-bonded Turntrans-46-50.1178.5-18065.2000113.5W242 C278 W279 W334 N335 F336 G552 D591W242-H550 AromaticContact CD1-CD2 3.9Å; W242-H550 AromaticContact NE1-CD2 3.52Å; C278-H550 PolarHBondContact SG-NE2 3.22Å; W279-H550 AromaticContact CE3-CE1 4Å; W279-H550 AromaticContact CZ3-CE1 3.74Å; W279-H550 AromaticContact CZ3-ND1 3.62Å; W334-H550 AromaticContact CE3-CD2 3.7Å; W334-H550 AromaticContact CE3-NE2 3.54Å; W334-H550 AromaticContact CZ3-CD2 3.77Å; W334-H550 AromaticContact CZ3-NE2 3.75Å; N335-H550 PolarHBondContact N-O 3.37Å; N335-H550 PolarHBondContact ND2-O 2.86Å; F336-H550 AromaticContact CD2-CE1 3.77Å; F336-H550 AromaticContact CE1-CE1 3.71Å; F336-H550 AromaticContact CE1-ND1 3.69Å; F336-H550 AromaticContact CE2-CE1 3.39Å; F336-H550 WeakPolarHBondContact CE2-CE1 3.19Å; F336-H550 AromaticContact CZ-CE1 3.35Å; F336-H550 WeakPolarHBondContact CZ-CE1 3.47Å; F336-H550 AromaticContact CZ-ND1 3.56Å; F336-H550 PolarHBondContact O-CE1 3Å; F336-H550 PolarHBondContact O-NE2 3.34Å; H550-G552 PolarHBondContact O-N 2.76Å; H550-G552 VanDerWaalsContact O-N 3.09Å; H550-D591 WeakPolarHBondContact CA-OD2 3.47Å; H550-D591 WeakPolarHBondContact CB-OD2 3.44Å; H550-D591 IonicContact CG-OD1 2.67Å; H550-D591 PolarHBondContact N-OD2 2.82Å; H550-D591 VanDerWaalsContact N-OD2 3.08Å; H550-D591 IonicContact ND1-OD1 3.87Å; H550-D591 PolarHBondContact ND1-OD1 2.84Å
551D83Confident91.4Very high27 Ų2725 Ų2514%0.14414%0.139CC..THydrogen-bonded Turntrans-71.44.2-178.870.4-19000114.2W334 L549 S553W334-D551 VanDerWaalsContact CD1-O 3.27Å; W334-D551 HydrophobicContact CD2-CB 3.99Å; W334-D551 HydrophobicContact CG-CB 4.3Å; W334-D551 HydrophobicContact CZ2-CB 3.98Å; L549-D551 VanDerWaalsContact C-N 3.28Å; L549-D551 VanDerWaalsContact CB-OD1 3.3Å; L549-D551 WeakPolarHBondContact CB-OD1 3.31Å; L549-D551 PolarHBondContact O-N 3.31Å; D551-S553 VanDerWaalsContact C-N 3.26Å; D551-S553 VanDerWaalsContact CG-OG 3.23Å; D551-S553 PolarHBondContact O-N 3.21Å; D551-S553 WeakPolarHBondContact OD1-CB 3.29Å; D551-S553 PolarHBondContact OD1-N 2.88Å; D551-S553 PolarHBondContact OD1-OG 3.38Å; D551-S553 PolarHBondContact OD2-OG 3.09Å
552G84.4Confident91.4Very high0 Ų027.6 Ų27.60%016%0.156CC..SBendtrans77.78.5-176.800000113.9K329 I333 L549 H550K329-G552 PolarHBondContact NZ-O 3.16Å; I333-G552 WeakPolarHBondContact O-CA 3.25Å; L549-G552 PolarHBondContact O-N 3.43Å; H550-G552 PolarHBondContact O-N 2.76Å; H550-G552 VanDerWaalsContact O-N 3.09Å
553S84.6Confident91.4Very high32 Ų3227 Ų2722%0.22415%0.152CC..  trans-68.4127.7171.8-70.20000110.2L549 D551L549-S553 PolarHBondContact N-O 2.81Å; D551-S553 VanDerWaalsContact C-N 3.26Å; D551-S553 VanDerWaalsContact CG-OG 3.23Å; D551-S553 PolarHBondContact O-N 3.21Å; D551-S553 WeakPolarHBondContact OD1-CB 3.29Å; D551-S553 PolarHBondContact OD1-N 2.88Å; D551-S553 PolarHBondContact OD1-OG 3.38Å; D551-S553 PolarHBondContact OD2-OG 3.09Å
554P88.2Confident91.3Very high22 Ų2233.6 Ų33.614%0.14318%0.181CC..EExtended strand (participates in β ladder)trans-80.6139.4-179.633.8-36000111.3I324 Q546 L548I324-P554 HydrophobicContact CB-CB 4.21Å; I324-P554 HydrophobicContact CB-CG 3.95Å; I324-P554 HydrophobicContact CG2-CG 3.81Å; Q546-P554 HydrophobicContact CB-CB 4.45Å; L548-P554 HydrophobicContact CD2-CB 4.06Å
555L89.1Confident91.3Very high61 Ų6134 Ų3432%0.31918%0.183SC..EExtended strand (participates in β ladder)trans-81.3175.4164.3-63.3-177.5000110.8Q546 S547 L549Q546-L555 WeakPolarHBondContact CG-O 3.46Å; Q546-L555 PolarHBondContact NE2-O 3.09Å; S547-L555 PolarHBondContact O-N 2.86Å; L549-L555 HydrophobicContact CD1-CD2 4.28Å; L549-L555 HydrophobicContact CD2-CD1 4.1Å; L549-L555 HydrophobicContact CD2-CD2 3.93Å; L549-L555 HydrophobicContact CD2-CG 4.09Å; L549-L555 HydrophobicContact CG-CD2 4.03Å; L549-L555 HydrophobicContact CG-CG 4.3Å
556S89.8Confident91.2Very high90 Ų9036.9 Ų36.963%0.62920%0.201SC*.EExtended strand (participates in β ladder)trans-58.8141.7177.6-720000111F558S556-F558 PolarHBondContact O-N 2.88Å
557P93.4Very high91.3Very high38 Ų3836.5 Ų36.525%0.24720%0.199CC..EExtended strand (participates in β ladder)trans-62.7133177.127.4-34.1000110A545 Q546 Q560A545-P557 WeakPolarHBondContact O-CA 3.26Å; Q546-P557 HydrophobicContact CG-CB 3.91Å; P557-Q560 HydrophobicContact CB-CG 4.41Å
558F94.6Very high91.4Very high25 Ų2539.2 Ų39.211%0.1122%0.219CC..EExtended strand (participates in β ladder)trans-110.6-12.517962.4-104.6000112.6A545 S547 S556 I579 Y587 I594A545-F558 HydrophobicContact CB-CE1 4.4Å; A545-F558 HydrophobicContact CB-CE2 3.85Å; A545-F558 HydrophobicContact CB-CZ 3.77Å; A545-F558 PolarHBondContact O-N 3.47Å; A545-F558 VanDerWaalsContact O-N 3.15Å; S547-F558 WeakPolarHBondContact OG-CE1 3.37Å; S556-F558 PolarHBondContact O-N 2.88Å; F558-I579 HydrophobicContact CD2-CG2 4.49Å; F558-I579 HydrophobicContact CE2-CD1 4.44Å; F558-I579 HydrophobicContact CE2-CG2 3.77Å; F558-Y587 HydrophobicContact CB-CD1 4.36Å; F558-Y587 HydrophobicContact CB-CD2 3.25Å; F558-Y587 HydrophobicContact CB-CE2 3.56Å; F558-Y587 HydrophobicContact CB-CG 3.68Å; F558-Y587 HydrophobicContact CD1-CD2 4.45Å; F558-Y587 HydrophobicContact CD1-CG 4.34Å; F558-Y587 AromaticContact CG-CD2 3.96Å; F558-Y587 HydrophobicContact CG-CD2 3.96Å; F558-Y587 HydrophobicContact CG-CG 4.28Å; F558-I594 HydrophobicContact CE1-CG1 4.34Å; F558-I594 HydrophobicContact CE1-CG2 4.27Å; F558-I594 HydrophobicContact CZ-CD1 4.02Å; F558-I594 HydrophobicContact CZ-CG1 4.05Å; F558-I594 HydrophobicContact CZ-CG2 3.7Å
559W96.1Very high91.7Very high23 Ų2342.4 Ų42.49%0.08724%0.239CC..EExtended strand (participates in β ladder)trans-145.1137.2176.6177.795.5000109.9F525 L543 S544 A545 D561 C577 K578 I579F525-W559 HydrophobicContact CZ-CH2 4.08Å; F525-W559 HydrophobicContact CZ-CZ3 4.21Å; L543-W559 HydrophobicContact CB-CH2 3.8Å; L543-W559 HydrophobicContact CB-CZ3 3.7Å; L543-W559 HydrophobicContact CD1-CH2 4.26Å; L543-W559 HydrophobicContact CG-CH2 4.48Å; S544-W559 CarbonylContact C-O 3.54Å; S544-W559 WeakPolarHBondContact CA-O 3.28Å; A545-W559 HydrophobicContact CB-CB 4.04Å; A545-W559 HydrophobicContact CB-CE3 3.92Å; A545-W559 PolarHBondContact N-O 2.96Å; W559-D561 HydrophobicContact CH2-CB 3.6Å; W559-D561 HydrophobicContact CZ2-CB 3.52Å; W559-D561 HydrophobicContact CZ3-CB 4.37Å; W559-C577 HydrophobicContact CH2-CB 4.26Å; W559-C577 HydrophobicContact CZ2-CB 4.31Å; W559-K578 PolarHBondContact NE1-O 3.28Å; W559-I579 HydrophobicContact CB-CG1 4.37Å; W559-I579 HydrophobicContact CD2-CD1 4.13Å; W559-I579 HydrophobicContact CD2-CG1 3.83Å; W559-I579 HydrophobicContact CE3-CD1 4.22Å; W559-I579 HydrophobicContact CE3-CG1 4.37Å; W559-I579 HydrophobicContact CG-CD1 4.26Å; W559-I579 HydrophobicContact CG-CG1 3.8Å
560Q95.7Very high92.1Very high101 Ų10148 Ų4847%0.47226%0.262SS..EExtended strand (participates in β ladder)trans-144.4149.9176-65.1-173.7-52.300109.3T321 L543 P557T321-Q560 PolarHBondContact OG1-NE2 3.25Å; L543-Q560 VanDerWaalsContact O-CA 3.24Å; L543-Q560 WeakPolarHBondContact O-CA 3.45Å; P557-Q560 HydrophobicContact CB-CG 4.41Å
561D96.1Very high92.8Very high55 Ų5550.7 Ų50.729%0.29428%0.275SS..EExtended strand (participates in β ladder)trans-151.7166.8177.5-164.37.8000110.6L543 W559 Y575L543-D561 HydrophobicContact CB-CB 4.09Å; L543-D561 HydrophobicContact CD1-CB 4.11Å; L543-D561 PolarHBondContact N-O 2.78Å; L543-D561 PolarHBondContact O-N 3.13Å; W559-D561 HydrophobicContact CH2-CB 3.6Å; W559-D561 HydrophobicContact CZ2-CB 3.52Å; W559-D561 HydrophobicContact CZ3-CB 4.37Å; D561-Y575 WeakPolarHBondContact OD2-CE1 3.31Å; D561-Y575 PolarHBondContact OD2-OH 3.2Å
562T96.3Very high93.4Very high56 Ų5652.8 Ų52.834%0.34430%0.296SS..EExtended strand (participates in β ladder)trans-137.8119.2176.2-59.20000110.4K540 V541 F564K540-T562 HydrophobicContact CG-CG2 4.14Å; V541-T562 CarbonylContact O-C 3.58Å; V541-T562 WeakPolarHBondContact O-CA 3.43Å; T562-F564 HydrophobicContact CG2-CD2 4.48Å; T562-F564 HydrophobicContact CG2-CE2 3.84Å; T562-F564 HydrophobicContact CG2-CZ 3.92Å
563A95Very high94Very high1 Ų156.3 Ų56.31%0.00831%0.311CS..EExtended strand (participates in β ladder)trans-102.5137176.500000111V541 L543 I565 Y575V541-A563 HydrophobicContact CB-CB 4.37Å; V541-A563 PolarHBondContact N-O 3.24Å; V541-A563 PolarHBondContact O-N 3.44Å; L543-A563 HydrophobicContact CD1-CB 4.4Å; A563-I565 HydrophobicContact CB-CD1 4.21Å; A563-I565 HydrophobicContact CB-CG1 4.1Å; A563-Y575 HydrophobicContact CB-CD1 3.95Å; A563-Y575 HydrophobicContact CB-CD2 3.74Å; A563-Y575 HydrophobicContact CB-CE1 3.94Å; A563-Y575 HydrophobicContact CB-CE2 3.72Å; A563-Y575 HydrophobicContact CB-CG 3.84Å
564F95.6Very high94.6Very high141 Ų14159.2 Ų59.262%0.61833%0.328SS*.EExtended strand (participates in β ladder)trans-110112.6169.4-63.5-85.5000108.1L539 K540 T562L539-F564 WeakPolarHBondContact O-CA 3.38Å; K540-F564 HydrophobicContact CB-CD1 4.3Å; K540-F564 HydrophobicContact CB-CE1 4.22Å; K540-F564 HydrophobicContact CD-CE1 4.11Å; K540-F564 HydrophobicContact CG-CD1 4.25Å; K540-F564 HydrophobicContact CG-CE1 3.81Å; K540-F564 HydrophobicContact CG-CZ 4.41Å; T562-F564 HydrophobicContact CG2-CD2 4.48Å; T562-F564 HydrophobicContact CG2-CE2 3.84Å; T562-F564 HydrophobicContact CG2-CZ 3.92Å
565I95.4Very high95.1Very high9 Ų961.3 Ų61.35%0.04633%0.334CS..EExtended strand (participates in β ladder)trans-122.8116-170.6-51177.2000109.2L527 A529 L539 V541 A563 L567 K573L527-I565 HydrophobicContact CD2-CD1 4.18Å; A529-I565 HydrophobicContact CB-CD1 4.07Å; A529-I565 HydrophobicContact CB-CG2 4.27Å; L539-I565 HydrophobicContact CB-CB 4.39Å; L539-I565 WeakPolarHBondContact CB-O 3.4Å; L539-I565 PolarHBondContact N-O 3.27Å; L539-I565 PolarHBondContact O-N 2.96Å; V541-I565 HydrophobicContact CG2-CD1 4.22Å; A563-I565 HydrophobicContact CB-CD1 4.21Å; A563-I565 HydrophobicContact CB-CG1 4.1Å; I565-L567 HydrophobicContact CG2-CD2 3.87Å; I565-L567 HydrophobicContact CG2-CG 3.96Å; I565-K573 HydrophobicContact CG2-CB 4.28Å; I565-K573 HydrophobicContact CG2-CD 4.3Å
566T95.2Very high95.4Very high61 Ų6163 Ų6337%0.37435%0.348SS..EExtended strand (participates in β ladder)trans-95.2132.4169.355.10000109.7F536 K537 K573F536-T566 HydrophobicContact CE2-CG2 4.47Å; F536-T566 HydrophobicContact CZ-CG2 3.83Å; K537-T566 CarbonylContact O-C 3.45Å; K537-T566 WeakPolarHBondContact O-CA 3.42Å; T566-K573 WeakPolarHBondContact O-CD 3.46Å; T566-K573 WeakPolarHBondContact O-CE 3.41Å; T566-K573 PolarHBondContact O-NZ 3.41Å; T566-K573 PolarHBondContact OG1-NZ 3.13Å
567L95.1Very high95.8Very high0 Ų059 Ų590%032%0.32CS..EExtended strand (participates in β ladder)trans-128.3120.3180-59.6168.1000110A529 N531 F536 K537 L539 I565 K573A529-L567 HydrophobicContact CB-CD1 4.07Å; N531-L567 HydrophobicContact CB-CB 3.7Å; N531-L567 HydrophobicContact CB-CD1 3.96Å; N531-L567 HydrophobicContact CB-CG 4.42Å; N531-L567 PolarHBondContact ND2-O 3.46Å; F536-L567 WeakPolarHBondContact CD2-O 3.46Å; K537-L567 HydrophobicContact CB-CB 4.31Å; K537-L567 PolarHBondContact N-O 3.48Å; K537-L567 PolarHBondContact O-N 3.05Å; L539-L567 HydrophobicContact CD1-CD1 3.62Å; L539-L567 HydrophobicContact CD1-CG 4.47Å; I565-L567 HydrophobicContact CG2-CD2 3.87Å; I565-L567 HydrophobicContact CG2-CG 3.96Å; L567-K573 HydrophobicContact CD2-CB 3.82Å; L567-K573 HydrophobicContact CD2-CD 4.07Å; L567-K573 HydrophobicContact CD2-CG 3.78Å
568S96.1Very high95.9Very high58 Ų5862.8 Ų62.841%0.40633%0.333SS..  trans-63.6162.6165.5-480000110.3N531 K570 E571N531-S568 PolarHBondContact ND2-O 3.14Å; S568-K570 PolarHBondContact O-N 3.33Å; S568-E571 VanDerWaalsContact CB-OE2 3.28Å; S568-E571 WeakPolarHBondContact CB-OE2 3.36Å; S568-E571 PolarHBondContact N-OE2 2.97Å; S568-E571 VanDerWaalsContact O-CB 3.24Å; S568-E571 WeakPolarHBondContact O-CB 3.43Å; S568-E571 PolarHBondContact O-N 3.15Å; S568-E571 PolarHBondContact OG-OE2 2.71Å
569P95.1Very high96Very high66 Ų6661.6 Ų61.643%0.42933%0.327SS..THydrogen-bonded Turntrans-50.3129.6174.5-29.337.4000111.6S534 E571S534-P569 WeakPolarHBondContact O-CB 3.48Å; S534-P569 VanDerWaalsContact O-CG 3.24Å; S534-P569 WeakPolarHBondContact O-CG 3.31Å; P569-E571 PolarHBondContact O-N 3.38Å; P569-E571 VanDerWaalsContact O-N 3.09Å
570K93.1Very high96Very high141 Ų14161.7 Ų61.761%0.61333%0.332SS*.THydrogen-bonded Turntrans62.77.5-179.8-50.1-59.5-176.4172.30116N531 M532 S533 S568N531-K570 WeakPolarHBondContact O-CA 3.32Å; N531-K570 PolarHBondContact O-N 3.23Å; M532-K570 PolarHBondContact O-NZ 3.46Å; S533-K570 PolarHBondContact O-N 3.38Å; S568-K570 PolarHBondContact O-N 3.33Å
571E96.8Very high95.8Very high58 Ų5858.4 Ų58.427%0.27132%0.315SS..  trans-75.2144.6179.2-170.6177.1-171.900111.8N531 S568 P569 K573N531-E571 PolarHBondContact N-O 3.1Å; S568-E571 VanDerWaalsContact CB-OE2 3.28Å; S568-E571 WeakPolarHBondContact CB-OE2 3.36Å; S568-E571 PolarHBondContact N-OE2 2.97Å; S568-E571 VanDerWaalsContact O-CB 3.24Å; S568-E571 WeakPolarHBondContact O-CB 3.43Å; S568-E571 PolarHBondContact O-N 3.15Å; S568-E571 PolarHBondContact OG-OE2 2.71Å; P569-E571 PolarHBondContact O-N 3.38Å; P569-E571 VanDerWaalsContact O-N 3.09Å; E571-K573 VanDerWaalsContact CD-CE 3.45Å; E571-K573 HydrophobicContact CG-CG 4.36Å; E571-K573 WeakPolarHBondContact OE1-CE 3.36Å; E571-K573 IonicContact OE1-NZ 2.96Å
572A96.3Very high95.7Very high71 Ų7159.8 Ų59.859%0.58733%0.329SS*.EExtended strand (participates in β ladder)trans-115132.7166.700000109.9A529 L530A529-A572 CarbonylContact O-C 3.44Å; A529-A572 VanDerWaalsContact O-CA 3.29Å; A529-A572 WeakPolarHBondContact O-CA 3.43Å; L530-A572 HydrophobicContact CD1-CB 3.94Å
573K97.2Very high95.5Very high73 Ų7360.6 Ų60.632%0.31733%0.329SS..EExtended strand (participates in β ladder)trans-124.9156.2171.8-72.8-172.6-176.8173.10111.3A529 I565 T566 L567 E571A529-K573 PolarHBondContact N-O 2.68Å; A529-K573 PolarHBondContact O-N 2.83Å; I565-K573 HydrophobicContact CG2-CB 4.28Å; I565-K573 HydrophobicContact CG2-CD 4.3Å; T566-K573 WeakPolarHBondContact O-CD 3.46Å; T566-K573 WeakPolarHBondContact O-CE 3.41Å; T566-K573 PolarHBondContact O-NZ 3.41Å; T566-K573 PolarHBondContact OG1-NZ 3.13Å; L567-K573 HydrophobicContact CD2-CB 3.82Å; L567-K573 HydrophobicContact CD2-CD 4.07Å; L567-K573 HydrophobicContact CD2-CG 3.78Å; E571-K573 VanDerWaalsContact CD-CE 3.45Å; E571-K573 HydrophobicContact CG-CG 4.36Å; E571-K573 WeakPolarHBondContact OE1-CE 3.36Å; E571-K573 IonicContact OE1-NZ 2.96Å
574T96.9Very high95.4Very high94 Ų9460.6 Ų60.658%0.57733%0.329SS*.EExtended strand (participates in β ladder)trans-118.5130.8175.463.40000110L527 L528L527-T574 CarbonylContact O-C 3.6Å; L527-T574 WeakPolarHBondContact O-CA 3.17Å; L528-T574 HydrophobicContact CD2-CG2 3.31Å
575Y97.5Very high95.1Very high66 Ų6655.6 Ų55.626%0.25931%0.312SS..EExtended strand (participates in β ladder)trans-108.2115.8172.4-174.7-92.8000109.3V526 L527 L543 D561 A563V526-Y575 CarbonylContact C-O 3.59Å; V526-Y575 WeakPolarHBondContact CA-O 3.4Å; L527-Y575 PolarHBondContact N-O 3.3Å; L527-Y575 PolarHBondContact O-N 3.14Å; L543-Y575 HydrophobicContact CD1-CD1 4.25Å; L543-Y575 HydrophobicContact CD1-CE1 4.09Å; D561-Y575 WeakPolarHBondContact OD2-CE1 3.31Å; D561-Y575 PolarHBondContact OD2-OH 3.2Å; A563-Y575 HydrophobicContact CB-CD1 3.95Å; A563-Y575 HydrophobicContact CB-CD2 3.74Å; A563-Y575 HydrophobicContact CB-CE1 3.94Å; A563-Y575 HydrophobicContact CB-CE2 3.72Å; A563-Y575 HydrophobicContact CB-CG 3.84Å
576P97.3Very high94.7Very high95 Ų9561.9 Ų61.962%0.61734%0.341SS*.EExtended strand (participates in β ladder)trans-77.8134.7-178.531.4-33.1000111.6
577C97.2Very high94.4Very high8 Ų863.4 Ų63.45%0.05434%0.34CS..EExtended strand (participates in β ladder)trans-124.2145.8177.6-57.90000110.2F525 W559F525-C577 HydrophobicContact CD1-CB 3.95Å; F525-C577 HydrophobicContact CD2-CB 3.76Å; F525-C577 HydrophobicContact CE1-CB 3.59Å; F525-C577 HydrophobicContact CE2-CB 3.38Å; F525-C577 HydrophobicContact CG-CB 4.03Å; F525-C577 HydrophobicContact CZ-CB 3.3Å; F525-C577 PolarHBondContact N-O 2.95Å; F525-C577 PolarHBondContact O-N 3.49Å; F525-C577 VanDerWaalsContact O-O 3.04Å; W559-C577 HydrophobicContact CH2-CB 4.26Å; W559-C577 HydrophobicContact CZ2-CB 4.31Å
578K96.4Very high93.9Very high116 Ų11665 Ų6550%0.50435%0.349SS..EExtended strand (participates in β ladder)trans-138.6128.7176.1-175.5179.6179.3-178.60110D522 I523 W559D522-K578 HydrophobicContact CB-CG 4.48Å; D522-K578 VanDerWaalsContact CG-CE 3.41Å; D522-K578 WeakPolarHBondContact OD2-CE 3.3Å; D522-K578 IonicContact OD2-NZ 2.73Å; D522-K578 PolarHBondContact OD2-NZ 2.9Å; I523-K578 WeakPolarHBondContact O-CA 3.33Å; W559-K578 PolarHBondContact NE1-O 3.28Å
579I96.6Very high93.3Very high0 Ų062.6 Ų62.60%033%0.332CS..EExtended strand (participates in β ladder)trans-115.7115.6170-58.2170.5000107I523 F525 A545 F558 W559 Q583 Y584 I596I523-I579 HydrophobicContact CB-CB 4.35Å; I523-I579 PolarHBondContact N-O 2.95Å; I523-I579 PolarHBondContact O-N 3.03Å; F525-I579 HydrophobicContact CE1-CD1 3.76Å; F525-I579 HydrophobicContact CE1-CG1 3.95Å; F525-I579 HydrophobicContact CZ-CD1 4.27Å; A545-I579 HydrophobicContact CB-CD1 3.83Å; F558-I579 HydrophobicContact CD2-CG2 4.49Å; F558-I579 HydrophobicContact CE2-CD1 4.44Å; F558-I579 HydrophobicContact CE2-CG2 3.77Å; W559-I579 HydrophobicContact CB-CG1 4.37Å; W559-I579 HydrophobicContact CD2-CD1 4.13Å; W559-I579 HydrophobicContact CD2-CG1 3.83Å; W559-I579 HydrophobicContact CE3-CD1 4.22Å; W559-I579 HydrophobicContact CE3-CG1 4.37Å; W559-I579 HydrophobicContact CG-CD1 4.26Å; W559-I579 HydrophobicContact CG-CG1 3.8Å; I579-Q583 HydrophobicContact CG2-CB 4.2Å; I579-Y584 HydrophobicContact CG2-CD1 3.91Å; I579-I596 HydrophobicContact CD1-CG2 4.28Å
580S94.9Very high92.6Very high25 Ų2560 Ų6018%0.17532%0.315CS..  trans-75.8155.4-178.668.60000112.6D522 S582 Q583 Y584D522-S580 WeakPolarHBondContact OD1-CA 3.4Å; D522-S580 WeakPolarHBondContact OD1-CB 3.13Å; S580-S582 PolarHBondContact O-N 2.83Å; S580-S582 PolarHBondContact OG-OG 3.34Å; S580-Q583 WeakPolarHBondContact O-CB 3.26Å; S580-Q583 PolarHBondContact O-N 2.98Å; S580-Q583 WeakPolarHBondContact OG-CG 3.46Å; S580-Q583 PolarHBondContact OG-N 2.62Å; S580-Q583 PolarHBondContact OG-OE1 2.67Å; S580-Y584 WeakPolarHBondContact O-CD1 3.44Å; S580-Y584 PolarHBondContact O-N 3.11Å
581Y92.7Very high91.9Very high33 Ų3353.8 Ų53.813%0.12929%0.288CS..Hα-helixtrans-51.5-43.9174.1174.4-113.4000112.3M519 G520 D522 Q583 Y584 S585 L646 E648M519-Y581 HydrophobicContact CE-CE2 3.97Å; M519-Y581 HydrophobicContact SD-CE2 4.23Å; G520-Y581 VanDerWaalsContact CA-CD2 3.45Å; D522-Y581 PolarHBondContact OD1-N 3.07Å; Y581-Q583 PolarHBondContact O-N 3.13Å; Y581-Y584 VanDerWaalsContact CA-CE1 3.42Å; Y581-Y584 HydrophobicContact CD2-CD2 4.46Å; Y581-Y584 HydrophobicContact CD2-CE1 4.38Å; Y581-Y584 AromaticContact CD2-CE2 3.63Å; Y581-Y584 HydrophobicContact CD2-CE2 3.63Å; Y581-Y584 AromaticContact CD2-CZ 3.59Å; Y581-Y584 WeakPolarHBondContact CD2-OH 3.34Å; Y581-Y584 HydrophobicContact CE2-CE2 4.12Å; Y581-Y584 PolarHBondContact O-N 3.31Å; Y581-S585 VanDerWaalsContact CE2-CB 3.45Å; Y581-S585 VanDerWaalsContact CZ-CB 3.49Å; Y581-S585 WeakPolarHBondContact O-CB 3.22Å; Y581-S585 PolarHBondContact O-N 3.28Å; Y581-S585 PolarHBondContact O-OG 3.2Å; Y581-L646 HydrophobicContact CE2-CD2 4.18Å; Y581-E648 WeakPolarHBondContact CE1-OE1 3.27Å; Y581-E648 PolarHBondContact OH-OE1 3.11Å; Y581-E648 VanDerWaalsContact OH-OE1 3.13Å
582S92.2Very high91.3Very high84 Ų8451.3 Ų51.359%0.58728%0.276SS*.Hα-helixtrans-61.7-25178.861.30000114.1S580S580-S582 PolarHBondContact O-N 2.83Å; S580-S582 PolarHBondContact OG-OG 3.34Å
583Q93.6Very high90.9Very high73 Ų7347.9 Ų47.934%0.34125%0.248SC..Hα-helixtrans-79.2-40.9177.9-73.9174.2-52.800111.7I579 S580 Y581 Y587I579-Q583 HydrophobicContact CG2-CB 4.2Å; S580-Q583 WeakPolarHBondContact O-CB 3.26Å; S580-Q583 PolarHBondContact O-N 2.98Å; S580-Q583 WeakPolarHBondContact OG-CG 3.46Å; S580-Q583 PolarHBondContact OG-N 2.62Å; S580-Q583 PolarHBondContact OG-OE1 2.67Å; Y581-Q583 PolarHBondContact O-N 3.13Å; Q583-Y587 WeakPolarHBondContact O-CD2 3.42Å; Q583-Y587 WeakPolarHBondContact O-CE2 3.44Å
584Y92.8Very high90.7Very high0 Ų044.4 Ų44.40%023%0.233CC..Hα-helixtrans-95.9-24.8-173.670.6-109.2000114.1M519 G520 Q521 I523 I579 S580 Y581 Q586 Y587 L588 I594 L617M519-Y584 HydrophobicContact SD-CE2 4.25Å; G520-Y584 PolarHBondContact N-OH 2.91Å; Q521-Y584 VanDerWaalsContact O-CE1 3.32Å; Q521-Y584 WeakPolarHBondContact O-CE1 3.4Å; Q521-Y584 PolarHBondContact O-OH 3.32Å; I523-Y584 HydrophobicContact CD1-CD1 3.85Å; I523-Y584 HydrophobicContact CD1-CE1 3.77Å; I523-Y584 HydrophobicContact CD1-CG 4.47Å; I523-Y584 HydrophobicContact CG1-CD1 4.26Å; I523-Y584 HydrophobicContact CG1-CE1 3.76Å; I579-Y584 HydrophobicContact CG2-CD1 3.91Å; S580-Y584 WeakPolarHBondContact O-CD1 3.44Å; S580-Y584 PolarHBondContact O-N 3.11Å; Y581-Y584 VanDerWaalsContact CA-CE1 3.42Å; Y581-Y584 HydrophobicContact CD2-CD2 4.46Å; Y581-Y584 HydrophobicContact CD2-CE1 4.38Å; Y581-Y584 AromaticContact CD2-CE2 3.63Å; Y581-Y584 HydrophobicContact CD2-CE2 3.63Å; Y581-Y584 AromaticContact CD2-CZ 3.59Å; Y581-Y584 WeakPolarHBondContact CD2-OH 3.34Å; Y581-Y584 HydrophobicContact CE2-CE2 4.12Å; Y581-Y584 PolarHBondContact O-N 3.31Å; Y584-Q586 VanDerWaalsContact C-N 3.31Å; Y584-Q586 PolarHBondContact O-N 2.9Å; Y584-Q586 VanDerWaalsContact O-N 3.17Å; Y584-Y587 PolarHBondContact O-N 3.39Å; Y584-L588 HydrophobicContact CD2-CD1 3.68Å; Y584-L588 HydrophobicContact CD2-CD2 4.07Å; Y584-L588 HydrophobicContact CD2-CG 3.87Å; Y584-L588 HydrophobicContact CE2-CD1 3.81Å; Y584-L588 HydrophobicContact CE2-CG 4.48Å; Y584-L588 PolarHBondContact O-N 3Å; Y584-I594 HydrophobicContact CD2-CD1 4.36Å; Y584-I594 HydrophobicContact CG-CD1 4.18Å; Y584-L617 HydrophobicContact CD2-CD1 4.3Å; Y584-L617 HydrophobicContact CE2-CD1 3.75Å
585S89.1Confident90.6Very high37 Ų3740.6 Ų40.626%0.25921%0.208SC..G310 helixtrans-56.3-39-167.761.80000114.5Y581 Y587Y581-S585 VanDerWaalsContact CE2-CB 3.45Å; Y581-S585 VanDerWaalsContact CZ-CB 3.49Å; Y581-S585 WeakPolarHBondContact O-CB 3.22Å; Y581-S585 PolarHBondContact O-N 3.28Å; Y581-S585 PolarHBondContact O-OG 3.2Å; S585-Y587 VanDerWaalsContact C-N 3.32Å
586Q87.3Confident90.4Very high140 Ų14037.5 Ų37.565%0.65420%0.196SC*.G310 helixtrans-80.6-10.1-179.968.5-174.9-11.600114.3Y584Y584-Q586 VanDerWaalsContact C-N 3.31Å; Y584-Q586 PolarHBondContact O-N 2.9Å; Y584-Q586 VanDerWaalsContact O-N 3.17Å
587Y87.4Confident90.3Very high94 Ų9433.1 Ų33.137%0.36917%0.168SC..G310 helixtrans-110.41.7-177.3-58.4-75.7000112.8S547 F558 Q583 Y584 S585 S589S547-Y587 WeakPolarHBondContact CB-O 3.49Å; S547-Y587 PolarHBondContact OG-O 3.37Å; F558-Y587 HydrophobicContact CB-CD1 4.36Å; F558-Y587 HydrophobicContact CB-CD2 3.25Å; F558-Y587 HydrophobicContact CB-CE2 3.56Å; F558-Y587 HydrophobicContact CB-CG 3.68Å; F558-Y587 HydrophobicContact CD1-CD2 4.45Å; F558-Y587 HydrophobicContact CD1-CG 4.34Å; F558-Y587 AromaticContact CG-CD2 3.96Å; F558-Y587 HydrophobicContact CG-CD2 3.96Å; F558-Y587 HydrophobicContact CG-CG 4.28Å; Q583-Y587 WeakPolarHBondContact O-CD2 3.42Å; Q583-Y587 WeakPolarHBondContact O-CE2 3.44Å; Y584-Y587 PolarHBondContact O-N 3.39Å; S585-Y587 VanDerWaalsContact C-N 3.32Å; Y587-S589 PolarHBondContact O-N 2.8Å
588L85.6Confident90.2Very high33 Ų3332.7 Ų32.717%0.17317%0.165CC..  trans-69.6132-179.4-75172.3000111.1M519 Y584 I594 L617M519-L588 HydrophobicContact CE-CD1 3.66Å; M519-L588 HydrophobicContact SD-CD1 3.59Å; M519-L588 VanDerWaalsContact SD-CD1 3.59Å; Y584-L588 HydrophobicContact CD2-CD1 3.68Å; Y584-L588 HydrophobicContact CD2-CD2 4.07Å; Y584-L588 HydrophobicContact CD2-CG 3.87Å; Y584-L588 HydrophobicContact CE2-CD1 3.81Å; Y584-L588 HydrophobicContact CE2-CG 4.48Å; Y584-L588 PolarHBondContact O-N 3Å; L588-I594 HydrophobicContact CD2-CD1 3.88Å; L588-I594 HydrophobicContact CD2-CG1 3.96Å; L588-L617 HydrophobicContact CD1-CD1 3.57Å; L588-L617 HydrophobicContact CD2-CD1 3.61Å; L588-L617 HydrophobicContact CG-CD1 4.25Å
589S84.4Confident90.1Very high7 Ų727.2 Ų27.25%0.04914%0.141CC..  trans-75167.8166.359.80000111.2L548 Y587 D591 K592L548-S589 VanDerWaalsContact O-CB 3.26Å; L548-S589 WeakPolarHBondContact O-CB 3.5Å; L548-S589 PolarHBondContact O-OG 2.96Å; Y587-S589 PolarHBondContact O-N 2.8Å; S589-D591 PolarHBondContact O-N 3.42Å; S589-K592 PolarHBondContact O-N 2.76Å; S589-K592 VanDerWaalsContact O-N 3.09Å
590T79.6Confident89.9Confident12 Ų1227.2 Ų27.27%0.07414%0.141CC..THydrogen-bonded Turntrans-56.9-36.6173-61.40000112.6E244 A253 K592 K706E244-T590 WeakPolarHBondContact OE2-CB 3.48Å; E244-T590 PolarHBondContact OE2-N 2.92Å; E244-T590 VanDerWaalsContact OE2-N 3.08Å; E244-T590 PolarHBondContact OE2-OG1 3.38Å; A253-T590 HydrophobicContact CB-CG2 3.44Å; A253-T590 VanDerWaalsContact CB-CG2 3.44Å; T590-K592 WeakPolarHBondContact O-CD 3.44Å; T590-K592 WeakPolarHBondContact O-CE 3.47Å; T590-K592 WeakPolarHBondContact O-CG 3.46Å; T590-K592 PolarHBondContact O-N 2.72Å; T590-K706 HydrophobicContact CG2-CB 4.11Å
591D77.4Confident89.8Confident10 Ų1027.8 Ų27.85%0.05314%0.141CC..THydrogen-bonded Turntrans-72.7-11.4178.2-62.5-85.5000114.5H550 S589 L593H550-D591 WeakPolarHBondContact CA-OD2 3.47Å; H550-D591 WeakPolarHBondContact CB-OD2 3.44Å; H550-D591 IonicContact CG-OD1 2.67Å; H550-D591 PolarHBondContact N-OD2 2.82Å; H550-D591 VanDerWaalsContact N-OD2 3.08Å; H550-D591 IonicContact ND1-OD1 3.87Å; H550-D591 PolarHBondContact ND1-OD1 2.84Å; S589-D591 PolarHBondContact O-N 3.42Å; D591-L593 VanDerWaalsContact C-N 3.29Å; D591-L593 HydrophobicContact CB-CD1 4.05Å; D591-L593 HydrophobicContact CB-CG 4Å; D591-L593 WeakPolarHBondContact O-CG 3.49Å; D591-L593 PolarHBondContact O-N 2.93Å
592K84.6Confident89.5Confident6 Ų627 Ų273%0.02614%0.138CC..  trans60.637.5175.1-51.8132172.5172.20113.1S589 T590 L617 Y619 D707S589-K592 PolarHBondContact O-N 2.76Å; S589-K592 VanDerWaalsContact O-N 3.09Å; T590-K592 WeakPolarHBondContact O-CD 3.44Å; T590-K592 WeakPolarHBondContact O-CE 3.47Å; T590-K592 WeakPolarHBondContact O-CG 3.46Å; T590-K592 PolarHBondContact O-N 2.72Å; K592-L617 HydrophobicContact CB-CB 4.25Å; K592-L617 PolarHBondContact O-N 3.18Å; K592-L617 VanDerWaalsContact O-N 3.14Å; K592-Y619 HydrophobicContact CB-CE2 4.12Å; K592-Y619 HydrophobicContact CD-CD2 3.95Å; K592-Y619 HydrophobicContact CD-CE2 3.3Å; K592-Y619 VanDerWaalsContact CE-CZ 3.49Å; K592-Y619 HydrophobicContact CG-CE2 3.51Å; K592-D707 PolarHBondContact NZ-O 3.4Å; K592-D707 IonicContact NZ-OD1 2.88Å; K592-D707 PolarHBondContact NZ-OD1 3.17Å; K592-D707 IonicContact NZ-OD2 3.83Å; K592-D707 PolarHBondContact NZ-OD2 3.48Å
593L89Confident89.2Confident0 Ų030 Ų300%014%0.141CC..EExtended strand (participates in β ladder)trans-107.5126.9-177.9-61.2179.3000111N335 S547 L548 D591 I614 I615 T616N335-L593 HydrophobicContact CB-CD1 3.47Å; N335-L593 VanDerWaalsContact CB-CD1 3.47Å; N335-L593 VanDerWaalsContact ND2-CD1 3.3Å; N335-L593 WeakPolarHBondContact ND2-CD1 3.46Å; S547-L593 WeakPolarHBondContact CA-O 3.28Å; L548-L593 HydrophobicContact CB-CB 4.29Å; L548-L593 PolarHBondContact N-O 3.07Å; D591-L593 VanDerWaalsContact C-N 3.29Å; D591-L593 HydrophobicContact CB-CD1 4.05Å; D591-L593 HydrophobicContact CB-CG 4Å; D591-L593 WeakPolarHBondContact O-CG 3.49Å; D591-L593 PolarHBondContact O-N 2.93Å; L593-I614 HydrophobicContact CB-CG2 4.27Å; L593-I614 HydrophobicContact CD2-CG2 3.99Å; L593-I615 WeakPolarHBondContact CA-O 3.48Å; L593-T616 HydrophobicContact CD2-CG2 3.87Å; L593-T616 WeakPolarHBondContact CD2-OG1 3.03Å
594I93.1Very high88.5Confident0 Ų030.9 Ų30.90%016%0.155CC..EExtended strand (participates in β ladder)trans-116.4121.4173-65.5167.3000108.1I523 A545 F558 Y584 L588 I596 I614 I615I523-I594 HydrophobicContact CD1-CD1 3.57Å; A545-I594 HydrophobicContact CB-CG2 4.24Å; F558-I594 HydrophobicContact CE1-CG1 4.34Å; F558-I594 HydrophobicContact CE1-CG2 4.27Å; F558-I594 HydrophobicContact CZ-CD1 4.02Å; F558-I594 HydrophobicContact CZ-CG1 4.05Å; F558-I594 HydrophobicContact CZ-CG2 3.7Å; Y584-I594 HydrophobicContact CD2-CD1 4.36Å; Y584-I594 HydrophobicContact CG-CD1 4.18Å; L588-I594 HydrophobicContact CD2-CD1 3.88Å; L588-I594 HydrophobicContact CD2-CG1 3.96Å; I594-I596 HydrophobicContact CG2-CG2 4.27Å; I594-I614 CarbonylContact O-C 3.58Å; I594-I614 WeakPolarHBondContact O-CA 3.33Å; I594-I615 HydrophobicContact CB-CB 4.39Å; I594-I615 PolarHBondContact N-O 2.74Å; I594-I615 PolarHBondContact O-N 2.96Å
595R93Very high87.9Confident13 Ų1332 Ų325%0.04916%0.163CC..EExtended strand (participates in β ladder)trans-91.9125.3167.7-173.9176.2-81.3-171.34.8109.2E316 Y318 I324 A545 Q546 L548 N612 K613 I614E316-R595 IonicContact OE1-CZ 3.84Å; E316-R595 IonicContact OE1-NH1 3.29Å; E316-R595 PolarHBondContact OE1-NH1 3.03Å; E316-R595 IonicContact OE1-NH2 2.72Å; E316-R595 IonicContact OE2-NH1 2.65Å; E316-R595 PolarHBondContact OE2-NH1 3.21Å; Y318-R595 PolarHBondContact OH-NH1 3.38Å; I324-R595 VanDerWaalsContact CD1-CD 3.41Å; A545-R595 WeakPolarHBondContact CA-O 3.31Å; Q546-R595 PolarHBondContact N-O 3.36Å; Q546-R595 PolarHBondContact O-N 2.99Å; L548-R595 HydrophobicContact CD1-CB 3.81Å; L548-R595 HydrophobicContact CD2-CB 4.03Å; L548-R595 HydrophobicContact CG-CB 3.87Å; R595-N612 HydrophobicContact CG-CB 4.47Å; R595-K613 WeakPolarHBondContact CA-O 3.4Å; R595-I614 HydrophobicContact CB-CG1 4.43Å; R595-I614 HydrophobicContact CG-CG1 4.41Å
596I95Very high87.2Confident1 Ų135.5 Ų35.51%0.00519%0.185CC..EExtended strand (participates in β ladder)trans-101.9139.4165.657.4169.7000109.3F511 F525 S544 A545 I579 I594 N612 K613 I615F511-I596 HydrophobicContact CB-CD1 3.9Å; F511-I596 HydrophobicContact CD1-CD1 3.67Å; F511-I596 HydrophobicContact CD2-CD1 3.77Å; F511-I596 HydrophobicContact CD2-CG1 3.92Å; F511-I596 HydrophobicContact CE1-CD1 4.05Å; F511-I596 HydrophobicContact CE2-CB 4.43Å; F511-I596 HydrophobicContact CE2-CD1 4.13Å; F511-I596 HydrophobicContact CE2-CG1 4.01Å; F511-I596 HydrophobicContact CG-CD1 3.51Å; F511-I596 HydrophobicContact CG-CG1 4.2Å; F511-I596 HydrophobicContact CZ-CB 4.46Å; F511-I596 HydrophobicContact CZ-CD1 4.24Å; F511-I596 HydrophobicContact CZ-CG1 4.37Å; F525-I596 HydrophobicContact CD2-CD1 3.8Å; F525-I596 HydrophobicContact CE2-CD1 3.7Å; F525-I596 HydrophobicContact CG-CD1 4.34Å; F525-I596 HydrophobicContact CZ-CD1 4.16Å; F525-I596 HydrophobicContact CZ-CG2 4.21Å; S544-I596 WeakPolarHBondContact O-CA 3.19Å; A545-I596 HydrophobicContact CB-CG2 3.97Å; I579-I596 HydrophobicContact CD1-CG2 4.28Å; I594-I596 HydrophobicContact CG2-CG2 4.27Å; I596-N612 CarbonylContact O-C 3.51Å; I596-N612 WeakPolarHBondContact O-CA 3.45Å; I596-N612 WeakPolarHBondContact O-CB 3.22Å; I596-K613 HydrophobicContact CD1-CB 4.24Å; I596-K613 HydrophobicContact CG1-CB 3.89Å; I596-K613 WeakPolarHBondContact CG1-O 3.31Å; I596-K613 PolarHBondContact N-O 2.65Å; I596-K613 PolarHBondContact O-N 3.35Å; I596-I615 HydrophobicContact CD1-CD1 4.02Å; I596-I615 HydrophobicContact CG1-CD1 4.24Å; I596-I615 HydrophobicContact CG2-CD1 4.05Å
597S95.1Very high86.8Confident3 Ų332.9 Ų32.92%0.02117%0.173CC..EExtended strand (participates in β ladder)trans-133.7148.1178.152.80000110.8G322 L543 S544 V611G322-S597 WeakPolarHBondContact O-CB 3.33Å; G322-S597 PolarHBondContact O-OG 3.05Å; L543-S597 WeakPolarHBondContact CA-O 3.43Å; S544-S597 PolarHBondContact N-O 3.24Å; S544-S597 PolarHBondContact O-N 3.18Å; S544-S597 PolarHBondContact O-OG 3.25Å; S597-V611 CarbonylContact C-O 3.58Å; S597-V611 WeakPolarHBondContact CA-O 3.42Å
598A95.1Very high86.8Confident0 Ų030.5 Ų30.50%016%0.164CC..EExtended strand (participates in β ladder)trans-130.2121.8171.900000108.9F511 L527 V541 N542 L543 L610 V611F511-A598 HydrophobicContact CE1-CB 4.27Å; F511-A598 HydrophobicContact CE2-CB 4.06Å; F511-A598 HydrophobicContact CZ-CB 3.48Å; F511-A598 VanDerWaalsContact CZ-CB 3.48Å; L527-A598 HydrophobicContact CD1-CB 4.12Å; V541-A598 HydrophobicContact CG1-CB 3.67Å; N542-A598 CarbonylContact O-C 3.58Å; N542-A598 WeakPolarHBondContact O-CA 3.47Å; L543-A598 HydrophobicContact CD2-CB 3.77Å; A598-L610 WeakPolarHBondContact O-CA 3.47Å; A598-V611 HydrophobicContact CB-CG1 3.67Å; A598-V611 PolarHBondContact N-O 2.85Å; A598-V611 PolarHBondContact O-N 2.98Å
599L94.7Very high87Confident0 Ų030.7 Ų30.70%017%0.165CC..EExtended strand (participates in β ladder)trans-104.6104.7170.5-175.769.9000108.8D319 L407 L416 V541 N542 K608 I609D319-L599 WeakPolarHBondContact O-CD2 3.24Å; L407-L599 HydrophobicContact CD1-CD2 3.88Å; L416-L599 HydrophobicContact CD1-CD1 4.26Å; L416-L599 HydrophobicContact CD2-CD1 4.38Å; V541-L599 WeakPolarHBondContact CA-O 3.45Å; N542-L599 PolarHBondContact N-O 2.87Å; N542-L599 PolarHBondContact O-N 3.01Å; L599-K608 HydrophobicContact CD1-CB 4.2Å; L599-I609 CarbonylContact C-O 3.59Å; L599-I609 WeakPolarHBondContact CA-O 3.25Å
600G92.5Very high87.3Confident0 Ų031.9 Ų31.90%017%0.171CC..EExtended strand (participates in β ladder)trans-87.4134.1176.400000112.2K540 K608 I609K540-G600 CarbonylContact O-C 3.6Å; G600-K608 WeakPolarHBondContact O-CA 3.47Å; G600-I609 PolarHBondContact N-O 2.75Å; G600-I609 PolarHBondContact O-N 3.25Å
601E90.9Very high87.9Confident37 Ų3732.6 Ų32.617%0.17318%0.175CC..EExtended strand (participates in β ladder)trans-122.8117.7174.8-42.8-167.1138.300108.6L539 K540 K608L539-E601 WeakPolarHBondContact CA-O 3.47Å; K540-E601 PolarHBondContact N-O 3.46Å; K540-E601 PolarHBondContact O-N 2.87Å; E601-K608 HydrophobicContact CB-CD 4.09Å; E601-K608 HydrophobicContact CG-CD 3.7Å; E601-K608 VanDerWaalsContact CG-NZ 3.32Å; E601-K608 IonicContact OE1-NZ 3.21Å; E601-K608 PolarHBondContact OE1-NZ 2.74Å; E601-K608 IonicContact OE2-NZ 3.26Å; E601-K608 PolarHBondContact OE2-NZ 3.07Å
602E88.1Confident88.5Confident16 Ų1635.2 Ų35.28%0.07519%0.189CC..EExtended strand (participates in β ladder)trans-85.5130.2172.8-168.5-162.4146.800109.6K537 L539 S604 S605K537-E602 HydrophobicContact CD-CG 4.06Å; K537-E602 WeakPolarHBondContact CD-OE1 3.41Å; K537-E602 WeakPolarHBondContact CD-OE2 3.3Å; K537-E602 IonicContact NZ-OE1 2.75Å; K537-E602 PolarHBondContact NZ-OE1 3.34Å; K537-E602 IonicContact NZ-OE2 2.7Å; K537-E602 PolarHBondContact NZ-OE2 2.95Å; L539-E602 HydrophobicContact CD2-CB 3.84Å; L539-E602 HydrophobicContact CD2-CG 4.15Å; E602-S604 PolarHBondContact O-N 2.88Å; E602-S604 PolarHBondContact OE1-OG 2.92Å; E602-S605 PolarHBondContact O-N 2.85Å
603K84.1Confident88.8Confident149 Ų14937.7 Ų37.765%0.64820%0.2SC*.THydrogen-bonded Turntrans-61-32.3-177.7-71.7-172-172.1159.60114.1D538D538-K603 HydrophobicContact CB-CD 4.35Å; D538-K603 PolarHBondContact O-N 3.06Å; D538-K603 IonicContact OD1-NZ 2.8Å; D538-K603 VanDerWaalsContact OD2-CD 3.3Å; D538-K603 WeakPolarHBondContact OD2-CD 3.43Å; D538-K603 VanDerWaalsContact OD2-CE 3.27Å; D538-K603 WeakPolarHBondContact OD2-CE 3.38Å; D538-K603 IonicContact OD2-NZ 2.71Å; D538-K603 PolarHBondContact OD2-NZ 3.09Å
604S78.7Confident88.9Confident90 Ų9038.4 Ų38.463%0.62920%0.203SC*.THydrogen-bonded Turntrans-90.7-4.3-177.427.40000114.3E602E602-S604 PolarHBondContact O-N 2.88Å; E602-S604 PolarHBondContact OE1-OG 2.92Å
605S80.4Confident88.8Confident25 Ų2538.5 Ų38.518%0.17520%0.204CC..  trans-130.1139.6-177.4-175.50000111.2E602 E607E602-S605 PolarHBondContact O-N 2.85Å; S605-E607 PolarHBondContact O-N 2.9Å; S605-E607 WeakPolarHBondContact OG-CB 3.46Å; S605-E607 PolarHBondContact OG-N 3.5Å; S605-E607 VanDerWaalsContact OG-N 3.16Å
606P76.3Confident88.6Confident109 Ų10938.5 Ų38.571%0.70821%0.206SC*.SBendtrans-70.6-11169.731.5-35.6000112.7
607E78.5Confident88.3Confident86 Ų8638.8 Ų38.840%0.40221%0.207SC..  trans-69.7142.8-179.9-65.9-178.5175.200112.1S605S605-E607 PolarHBondContact O-N 2.9Å; S605-E607 WeakPolarHBondContact OG-CB 3.46Å; S605-E607 PolarHBondContact OG-N 3.5Å; S605-E607 VanDerWaalsContact OG-N 3.16Å
608K86.8Confident87.8Confident43 Ų4340.3 Ų40.319%0.18722%0.217CC..EExtended strand (participates in β ladder)trans-118.7140.8179.4-58.4-71.4176.5177.10107.8L407 L416 L599 G600 E601L407-K608 HydrophobicContact CD2-CG 4.15Å; L416-K608 HydrophobicContact CD2-CB 3.49Å; L416-K608 VanDerWaalsContact CD2-CB 3.49Å; L416-K608 HydrophobicContact CD2-CG 4.22Å; L599-K608 HydrophobicContact CD1-CB 4.2Å; G600-K608 WeakPolarHBondContact O-CA 3.47Å; E601-K608 HydrophobicContact CB-CD 4.09Å; E601-K608 HydrophobicContact CG-CD 3.7Å; E601-K608 VanDerWaalsContact CG-NZ 3.32Å; E601-K608 IonicContact OE1-NZ 3.21Å; E601-K608 PolarHBondContact OE1-NZ 2.74Å; E601-K608 IonicContact OE2-NZ 3.26Å; E601-K608 PolarHBondContact OE2-NZ 3.07Å
609I89.6Confident87.1Confident37 Ų3742.2 Ų42.219%0.1923%0.225CC..EExtended strand (participates in β ladder)trans-115119.4-177.4-57164.6000107.5V507 L509 L599 G600V507-I609 HydrophobicContact CB-CD1 3.6Å; V507-I609 HydrophobicContact CG1-CD1 3.87Å; L509-I609 HydrophobicContact CB-CG2 4.39Å; L509-I609 HydrophobicContact CD1-CB 4.27Å; L509-I609 HydrophobicContact CD1-CG2 3.96Å; L509-I609 HydrophobicContact CG-CG2 4.05Å; L599-I609 CarbonylContact C-O 3.59Å; L599-I609 WeakPolarHBondContact CA-O 3.25Å; G600-I609 PolarHBondContact N-O 2.75Å; G600-I609 PolarHBondContact O-N 3.25Å
610L90.7Very high86.5Confident33 Ų3344 Ų4417%0.17324%0.237CC..EExtended strand (participates in β ladder)trans-105.8128.8175.1179.966.3000109.4Y318 L416 A598Y318-L610 HydrophobicContact CD1-CD1 4.01Å; Y318-L610 HydrophobicContact CD1-CD2 4.22Å; Y318-L610 HydrophobicContact CD2-CD2 3.77Å; Y318-L610 HydrophobicContact CE1-CD1 4.02Å; Y318-L610 HydrophobicContact CE1-CD2 3.99Å; Y318-L610 HydrophobicContact CE2-CD2 3.56Å; Y318-L610 HydrophobicContact CG-CD1 4.48Å; Y318-L610 HydrophobicContact CG-CD2 4.13Å; L416-L610 HydrophobicContact CD1-CB 4.3Å; L416-L610 HydrophobicContact CD1-CD2 4.06Å; A598-L610 WeakPolarHBondContact O-CA 3.47Å
611V91.9Very high86.1Confident26 Ų2648 Ų4816%0.15826%0.264CS..EExtended strand (participates in β ladder)trans-129142.516464.90000109.2L509 F511 L527 S597 A598L509-V611 HydrophobicContact CB-CB 4.21Å; L509-V611 HydrophobicContact CB-CG1 3.62Å; L509-V611 HydrophobicContact CD1-CG1 4.48Å; F511-V611 HydrophobicContact CD2-CG1 4.22Å; F511-V611 HydrophobicContact CD2-CG2 4.32Å; F511-V611 HydrophobicContact CE2-CG1 3.9Å; F511-V611 HydrophobicContact CZ-CG1 4.43Å; L527-V611 HydrophobicContact CD1-CG1 4.25Å; S597-V611 CarbonylContact C-O 3.58Å; S597-V611 WeakPolarHBondContact CA-O 3.42Å; A598-V611 HydrophobicContact CB-CG1 3.67Å; A598-V611 PolarHBondContact N-O 2.85Å; A598-V611 PolarHBondContact O-N 2.98Å
612N91.4Very high86.2Confident66 Ų6646.5 Ų46.535%0.35326%0.258SS..EExtended strand (participates in β ladder)trans-136.5162.2174.468.766.5000111R595 I596R595-N612 HydrophobicContact CG-CB 4.47Å; I596-N612 CarbonylContact O-C 3.51Å; I596-N612 WeakPolarHBondContact O-CA 3.45Å; I596-N612 WeakPolarHBondContact O-CB 3.22Å
613K90.3Very high86.6Confident57 Ų5748.8 Ų48.825%0.24827%0.273CS..EExtended strand (participates in β ladder)trans-151137.4173.2-174.3176.3-178.471.40109.5F511 R595 I596F511-K613 HydrophobicContact CB-CB 4.12Å; F511-K613 HydrophobicContact CB-CD 3.94Å; F511-K613 HydrophobicContact CD2-CB 4Å; F511-K613 HydrophobicContact CG-CB 4.47Å; R595-K613 WeakPolarHBondContact CA-O 3.4Å; I596-K613 HydrophobicContact CD1-CB 4.24Å; I596-K613 HydrophobicContact CG1-CB 3.89Å; I596-K613 WeakPolarHBondContact CG1-O 3.31Å; I596-K613 PolarHBondContact N-O 2.65Å; I596-K613 PolarHBondContact O-N 3.35Å
614I90.3Very high87.3Confident15 Ų1542 Ų428%0.07724%0.244CC..EExtended strand (participates in β ladder)trans-92.7131.2169.6-60.6172000108.7L548 L593 I594 R595L548-I614 HydrophobicContact CD1-CD1 4.07Å; L548-I614 HydrophobicContact CD1-CG1 4.2Å; L593-I614 HydrophobicContact CB-CG2 4.27Å; L593-I614 HydrophobicContact CD2-CG2 3.99Å; I594-I614 CarbonylContact O-C 3.58Å; I594-I614 WeakPolarHBondContact O-CA 3.33Å; R595-I614 HydrophobicContact CB-CG1 4.43Å; R595-I614 HydrophobicContact CG-CG1 4.41Å
615I90.8Very high88.2Confident2 Ų240.5 Ų40.51%0.0123%0.229CC..EExtended strand (participates in β ladder)trans-108.9124.8175.4-57.2175.1000107.1L513 P517 I523 L593 I594 I596L513-I615 HydrophobicContact CD2-CD1 3.8Å; L513-I615 HydrophobicContact CD2-CG1 4.16Å; P517-I615 HydrophobicContact CB-CG2 3.58Å; P517-I615 HydrophobicContact CG-CG2 3.73Å; I523-I615 HydrophobicContact CG2-CD1 3.93Å; L593-I615 WeakPolarHBondContact CA-O 3.48Å; I594-I615 HydrophobicContact CB-CB 4.39Å; I594-I615 PolarHBondContact N-O 2.74Å; I594-I615 PolarHBondContact O-N 2.96Å; I596-I615 HydrophobicContact CD1-CD1 4.02Å; I596-I615 HydrophobicContact CG1-CD1 4.24Å; I596-I615 HydrophobicContact CG2-CD1 4.05Å
616T89Confident89Confident14 Ų1441.4 Ų41.49%0.08623%0.233CC..EExtended strand (participates in β ladder)trans-105.5123.3174.1-55.30000108.7S172 W175 P517 L593S172-T616 PolarHBondContact OG-OG1 3.49Å; W175-T616 HydrophobicContact CB-CG2 4.43Å; W175-T616 HydrophobicContact CG-CG2 4.49Å; P517-T616 VanDerWaalsContact CG-O 3.31Å; P517-T616 WeakPolarHBondContact CG-O 3.36Å; L593-T616 HydrophobicContact CD2-CG2 3.87Å; L593-T616 WeakPolarHBondContact CD2-OG1 3.03Å
617L88.6Confident90Very high6 Ų640.2 Ų40.23%0.03122%0.22CC..  trans-75.5136.4-180-61.2-178.7000112.2P517 M519 I523 Y584 L588 K592 Y619P517-L617 HydrophobicContact CB-CD2 4Å; P517-L617 CarbonylContact O-C 3.6Å; P517-L617 VanDerWaalsContact O-CA 3.32Å; P517-L617 WeakPolarHBondContact O-CA 3.49Å; M519-L617 HydrophobicContact SD-CD1 3.76Å; I523-L617 HydrophobicContact CD1-CD2 3.99Å; I523-L617 HydrophobicContact CG1-CD2 4.4Å; Y584-L617 HydrophobicContact CD2-CD1 4.3Å; Y584-L617 HydrophobicContact CE2-CD1 3.75Å; L588-L617 HydrophobicContact CD1-CD1 3.57Å; L588-L617 HydrophobicContact CD2-CD1 3.61Å; L588-L617 HydrophobicContact CG-CD1 4.25Å; K592-L617 HydrophobicContact CB-CB 4.25Å; K592-L617 PolarHBondContact O-N 3.18Å; K592-L617 VanDerWaalsContact O-N 3.14Å; L617-Y619 HydrophobicContact CB-CE2 4.3Å
618S84.4Confident90.7Very high35 Ų3538.2 Ų38.225%0.24522%0.222CC..BIsolated β-bridgetrans-86143.6173.8-171.70000111.8P517 M519P517-S618 PolarHBondContact O-N 2.72Å; M519-S618 WeakPolarHBondContact CB-O 3.08Å; M519-S618 PolarHBondContact N-O 3.42Å
619Y81.8Confident91.1Very high40 Ų4039.6 Ų39.616%0.15724%0.242CC..  trans-122.2153.2178.6-80.2-101.1000110.6M519 K592 L617 F705 I708M519-Y619 HydrophobicContact CB-CD1 4.18Å; M519-Y619 HydrophobicContact CB-CD2 4.23Å; M519-Y619 HydrophobicContact CB-CE1 3.95Å; M519-Y619 HydrophobicContact CB-CE2 3.95Å; M519-Y619 HydrophobicContact CB-CG 4.33Å; M519-Y619 WeakPolarHBondContact CE-OH 3.43Å; M519-Y619 HydrophobicContact CG-CD1 4.21Å; M519-Y619 HydrophobicContact CG-CE1 3.56Å; M519-Y619 HydrophobicContact CG-CE2 4.15Å; M519-Y619 HydrophobicContact SD-CE1 4.46Å; M519-Y619 PolarHBondContact SD-OH 3.3Å; K592-Y619 HydrophobicContact CB-CE2 4.12Å; K592-Y619 HydrophobicContact CD-CD2 3.95Å; K592-Y619 HydrophobicContact CD-CE2 3.3Å; K592-Y619 VanDerWaalsContact CE-CZ 3.49Å; K592-Y619 HydrophobicContact CG-CE2 3.51Å; L617-Y619 HydrophobicContact CB-CE2 4.3Å; Y619-F705 HydrophobicContact CE1-CB 3.78Å; Y619-F705 HydrophobicContact CE1-CG 4.39Å; Y619-I708 HydrophobicContact CD1-CD1 3.71Å; Y619-I708 HydrophobicContact CD1-CG1 3.94Å; Y619-I708 HydrophobicContact CE1-CD1 4.41Å
620P81.2Confident91.5Very high38 Ų3838.1 Ų38.125%0.24724%0.235CC..PPolyproline II helixtrans-62.7139.1168.427.9-33.4000109.8F642 S643 P645 I708P620-F642 HydrophobicContact CG-CE2 3.98Å; P620-F642 HydrophobicContact CG-CZ 4.41Å; P620-S643 WeakPolarHBondContact CG-O 3.43Å; P620-P645 HydrophobicContact CG-CB 3.72Å; P620-P645 HydrophobicContact CG-CG 3.65Å; P620-I708 WeakPolarHBondContact O-CG2 3.43Å
621S83.6Confident91.8Very high83 Ų8338.3 Ų38.358%0.5824%0.236SC*.PPolyproline II helixtrans-77.2156.3176.456.10000111.6
622I94.4Very high92.1Very high7 Ų737.8 Ų37.84%0.03623%0.233CC..PPolyproline II helixtrans-82.1127164.7-61.6173.4000107.8I624 V640 F642 L655 A698 M700 I708I622-I624 HydrophobicContact CG2-CG1 4.09Å; I622-V640 HydrophobicContact CG2-CG1 3.43Å; I622-V640 VanDerWaalsContact CG2-CG1 3.43Å; I622-F642 HydrophobicContact CG1-CD2 4.07Å; I622-L655 HydrophobicContact CD1-CD1 4.41Å; I622-A698 HydrophobicContact CD1-CB 4.05Å; I622-A698 HydrophobicContact CG2-CB 3.99Å; I622-M700 HydrophobicContact CD1-CB 3.88Å; I622-I708 HydrophobicContact CD1-CG2 4.47Å; I622-I708 WeakPolarHBondContact CD1-O 3.25Å; I622-I708 HydrophobicContact CG1-CG2 4.09Å
623T96.4Very high92.3Very high64 Ų6440.5 Ų40.539%0.39325%0.247SC..EExtended strand (participates in β ladder)trans-95.7133.7172.9-59.40000109.5V640 I641T623-V640 WeakPolarHBondContact O-CA 3.28Å; T623-I641 PolarHBondContact N-O 2.84Å; T623-I641 PolarHBondContact O-N 3.27Å
624I98Very high92.6Very high6 Ų642 Ų423%0.03126%0.255CS..EExtended strand (participates in β ladder)trans-125.6118.1179.3-54.7174000108.4I622 I638 Q639 V640 I696 A698 R712I622-I624 HydrophobicContact CG2-CG1 4.09Å; I624-I638 HydrophobicContact CG2-CG2 3.57Å; I624-Q639 CarbonylContact C-O 3.53Å; I624-Q639 WeakPolarHBondContact CA-O 3.32Å; I624-V640 HydrophobicContact CG1-CG1 4.41Å; I624-V640 HydrophobicContact CG1-CG2 4.45Å; I624-I696 HydrophobicContact CD1-CG2 4.04Å; I624-I696 HydrophobicContact CG2-CB 4.43Å; I624-I696 HydrophobicContact CG2-CD1 4.2Å; I624-I696 HydrophobicContact CG2-CG2 4.11Å; I624-A698 HydrophobicContact CD1-CB 3.78Å; I624-A698 HydrophobicContact CG1-CB 4.49Å; I624-R712 HydrophobicContact CB-CB 3.8Å; I624-R712 HydrophobicContact CG2-CB 3.9Å
625N97.9Very high92.9Very high59 Ų5946.3 Ų46.332%0.31628%0.284SS..EExtended strand (participates in β ladder)trans-107.9134.7176.7-60.8-36.2000109.6L627 I638 Q639N625-L627 HydrophobicContact CB-CD2 4.14Å; N625-I638 CarbonylContact O-C 3.57Å; N625-I638 WeakPolarHBondContact O-CA 3.4Å; N625-Q639 HydrophobicContact CB-CB 4.24Å; N625-Q639 PolarHBondContact N-O 3Å; N625-Q639 PolarHBondContact ND2-OE1 3.11Å; N625-Q639 PolarHBondContact O-N 2.92Å
626V97.4Very high93.3Very high43 Ų4346.4 Ų46.426%0.26129%0.285SS..EExtended strand (participates in β ladder)trans-96.3119.7173-175.20000107.7G628 L636 I696 R712 V714V626-G628 VanDerWaalsContact C-N 3.34Å; V626-G628 PolarHBondContact O-N 3.06Å; V626-L636 HydrophobicContact CG1-CD1 3.56Å; V626-L636 HydrophobicContact CG1-CD2 4.08Å; V626-L636 HydrophobicContact CG1-CG 4.12Å; V626-I696 HydrophobicContact CG2-CD1 3.92Å; V626-R712 HydrophobicContact CG2-CG 4.28Å; V626-V714 HydrophobicContact CG2-CG2 3.59Å
627L96.9Very high93.7Very high84 Ų8447.6 Ų47.644%0.4429%0.294SS..  trans-97.336.1-168.7-56.1-175000113N625 S637 Q639 I683N625-L627 HydrophobicContact CB-CD2 4.14Å; L627-S637 WeakPolarHBondContact CB-O 3.37Å; L627-S637 PolarHBondContact N-O 2.97Å; L627-Q639 HydrophobicContact CD1-CB 3.9Å; L627-Q639 HydrophobicContact CD2-CB 4.2Å; L627-Q639 HydrophobicContact CG-CB 4.11Å; L627-I683 HydrophobicContact CD1-CD1 4.45Å
628G94.1Very high94.1Very high44 Ų4447.3 Ų47.345%0.45429%0.292SS..SBendtrans170.4176.5-178.900000112.2V626V626-G628 VanDerWaalsContact C-N 3.34Å; V626-G628 PolarHBondContact O-N 3.06Å
629A95.1Very high94.8Very high73 Ų7347.8 Ų47.860%0.60329%0.291SS*.  trans-70.2133.5169.400000109.5I631A629-I631 HydrophobicContact CB-CD1 4.23Å; A629-I631 HydrophobicContact CB-CG1 4.26Å
630A97.3Very high95.5Very high5 Ų546 Ų464%0.04128%0.284CS..  trans-87.8112.3173.900000108.8L636 V714 V716 D717A630-L636 HydrophobicContact CB-CD1 4.21Å; A630-L636 HydrophobicContact CB-CD2 3.78Å; A630-V714 HydrophobicContact CB-CG1 3.53Å; A630-V716 HydrophobicContact CB-CB 4.45Å; A630-V716 HydrophobicContact CB-CG1 4.46Å; A630-V716 HydrophobicContact CB-CG2 4.09Å; A630-V716 CarbonylContact O-C 3.57Å; A630-V716 WeakPolarHBondContact O-CA 3.24Å; A630-D717 PolarHBondContact O-N 3.39Å
631I97.6Very high96.2Very high37 Ų3745.3 Ų45.319%0.1928%0.278CS..BIsolated β-bridgetrans-127.2137.1-178.1-57.9172.5000108.4A629 N633 Q634 D717 A719A629-I631 HydrophobicContact CB-CD1 4.23Å; A629-I631 HydrophobicContact CB-CG1 4.26Å; I631-N633 PolarHBondContact O-N 3.25Å; I631-Q634 HydrophobicContact CB-CB 4.17Å; I631-Q634 HydrophobicContact CB-CG 4.12Å; I631-Q634 HydrophobicContact CG2-CG 4.01Å; I631-Q634 PolarHBondContact O-N 2.77Å; I631-Q634 VanDerWaalsContact O-N 3.14Å; I631-D717 WeakPolarHBondContact CA-O 3.45Å; I631-A719 HydrophobicContact CG2-CB 3.87Å
632V97.1Very high96.7Very high16 Ų1641.5 Ų41.510%0.09725%0.251CS..THydrogen-bonded Turntrans-54.7132.8177.6173.90000110.4Q634 V716 D717V632-Q634 PolarHBondContact O-N 2.91Å; V632-V716 HydrophobicContact CG2-CG1 3.79Å; V632-D717 WeakPolarHBondContact CG2-O 3.38Å; V632-D717 PolarHBondContact N-O 3.02Å
633N96.3Very high96.6Very high122 Ų12243 Ų4365%0.65226%0.262SS*.THydrogen-bonded Turntrans62.217.3-179.5-58.2-36.5000115.5I631 P688I631-N633 PolarHBondContact O-N 3.25Å; N633-P688 PolarHBondContact N-O 3.12Å
634Q96.9Very high96.5Very high89 Ų8939.9 Ų39.942%0.41624%0.243SC..SBendtrans-112.7149.5172.2-60.8-16810.500112I631 V632 P688I631-Q634 HydrophobicContact CB-CB 4.17Å; I631-Q634 HydrophobicContact CB-CG 4.12Å; I631-Q634 HydrophobicContact CG2-CG 4.01Å; I631-Q634 PolarHBondContact O-N 2.77Å; I631-Q634 VanDerWaalsContact O-N 3.14Å; V632-Q634 PolarHBondContact O-N 2.91Å; Q634-P688 VanDerWaalsContact O-CD 3.27Å; Q634-P688 WeakPolarHBondContact O-CD 3.31Å
635P97.1Very high96.1Very high106 Ų10640.9 Ų40.969%0.68825%0.25SC*.  trans-60.8136.6174.9-23.234.2000112.8T686P635-T686 CarbonylContact C-O 3.55Å
636L97.4Very high95.8Very high3 Ų338.1 Ų38.12%0.01624%0.235CC..EExtended strand (participates in β ladder)trans-127.4123176.9-177.363.4000109.9V626 A630 I638 E685 T686 P688V626-L636 HydrophobicContact CG1-CD1 3.56Å; V626-L636 HydrophobicContact CG1-CD2 4.08Å; V626-L636 HydrophobicContact CG1-CG 4.12Å; A630-L636 HydrophobicContact CB-CD1 4.21Å; A630-L636 HydrophobicContact CB-CD2 3.78Å; L636-I638 HydrophobicContact CD2-CD1 4.38Å; L636-I638 HydrophobicContact CD2-CG1 4.37Å; L636-I638 HydrophobicContact CG-CG1 4.28Å; L636-E685 WeakPolarHBondContact O-CA 3.37Å; L636-T686 HydrophobicContact CB-CG2 4.19Å; L636-T686 HydrophobicContact CD2-CG2 4.45Å; L636-T686 PolarHBondContact N-O 2.91Å; L636-T686 PolarHBondContact O-N 2.9Å; L636-P688 HydrophobicContact CB-CG 4.18Å; L636-P688 HydrophobicContact CD2-CG 3.95Å
637S97.8Very high95.5Very high40 Ų4040.8 Ų40.828%0.2826%0.255SS..EExtended strand (participates in β ladder)trans-89.7132.8172.4-740000111.1L627 L684L627-S637 WeakPolarHBondContact CB-O 3.37Å; L627-S637 PolarHBondContact N-O 2.97Å; S637-L684 CarbonylContact C-O 3.58Å; S637-L684 WeakPolarHBondContact CA-O 3.32Å
638I97.8Very high95.2Very high0 Ų039.8 Ų39.80%025%0.249CC..EExtended strand (participates in β ladder)trans-126.6125.5-179.7-61.3160000108.2I624 N625 L636 V640 F663 I683 L684 T686 I696I624-I638 HydrophobicContact CG2-CG2 3.57Å; N625-I638 CarbonylContact O-C 3.57Å; N625-I638 WeakPolarHBondContact O-CA 3.4Å; L636-I638 HydrophobicContact CD2-CD1 4.38Å; L636-I638 HydrophobicContact CD2-CG1 4.37Å; L636-I638 HydrophobicContact CG-CG1 4.28Å; I638-V640 HydrophobicContact CG2-CG2 4.23Å; I638-F663 HydrophobicContact CD1-CE2 4.07Å; I638-F663 HydrophobicContact CD1-CZ 3.57Å; I638-I683 CarbonylContact O-C 3.09Å; I638-I683 WeakPolarHBondContact O-CA 3.28Å; I638-L684 PolarHBondContact N-O 2.77Å; I638-L684 PolarHBondContact O-N 2.67Å; I638-T686 HydrophobicContact CD1-CG2 3.77Å; I638-I696 HydrophobicContact CD1-CD1 3.57Å; I638-I696 HydrophobicContact CD1-CG1 4.27Å; I638-I696 HydrophobicContact CG1-CD1 3.89Å; I638-I696 HydrophobicContact CG2-CD1 4.07Å
639Q98Very high95.2Very high45 Ų4542.4 Ų42.421%0.2125%0.249CC..EExtended strand (participates in β ladder)trans-99.4126.5173.6177.2-171.454.600110.2I624 N625 L627 I641 S681 I682I624-Q639 CarbonylContact C-O 3.53Å; I624-Q639 WeakPolarHBondContact CA-O 3.32Å; N625-Q639 HydrophobicContact CB-CB 4.24Å; N625-Q639 PolarHBondContact N-O 3Å; N625-Q639 PolarHBondContact ND2-OE1 3.11Å; N625-Q639 PolarHBondContact O-N 2.92Å; L627-Q639 HydrophobicContact CD1-CB 3.9Å; L627-Q639 HydrophobicContact CD2-CB 4.2Å; L627-Q639 HydrophobicContact CG-CB 4.11Å; Q639-I641 HydrophobicContact CG-CD1 4.27Å; Q639-I641 HydrophobicContact CG-CG1 3.93Å; Q639-S681 PolarHBondContact NE2-OG 2.94Å; Q639-I682 CarbonylContact C-O 3.59Å; Q639-I682 VanDerWaalsContact CA-O 3.29Å; Q639-I682 WeakPolarHBondContact CA-O 3.34Å
640V97.6Very high95.1Very high2 Ų238.9 Ų38.91%0.01222%0.22CC..EExtended strand (participates in β ladder)trans-112.8128.1175.9-173.50000109.2I622 T623 I624 I638 L655 V657 S681 I682 L684I622-V640 HydrophobicContact CG2-CG1 3.43Å; I622-V640 VanDerWaalsContact CG2-CG1 3.43Å; T623-V640 WeakPolarHBondContact O-CA 3.28Å; I624-V640 HydrophobicContact CG1-CG1 4.41Å; I624-V640 HydrophobicContact CG1-CG2 4.45Å; I638-V640 HydrophobicContact CG2-CG2 4.23Å; V640-L655 HydrophobicContact CB-CD2 3.92Å; V640-L655 HydrophobicContact CG1-CD1 3.97Å; V640-L655 HydrophobicContact CG1-CD2 3.74Å; V640-L655 HydrophobicContact CG2-CD2 4.36Å; V640-V657 HydrophobicContact CG2-CG2 4.3Å; V640-S681 WeakPolarHBondContact O-CA 3.3Å; V640-I682 PolarHBondContact N-O 2.87Å; V640-I682 PolarHBondContact O-N 2.89Å; V640-L684 HydrophobicContact CG2-CD1 4.39Å
641I96.1Very high95Very high24 Ų2442.1 Ų42.112%0.12323%0.234CC..EExtended strand (participates in β ladder)trans-124.1132.7-174.8-50.5176000109.6T623 Q639 Q679 A680T623-I641 PolarHBondContact N-O 2.84Å; T623-I641 PolarHBondContact O-N 3.27Å; Q639-I641 HydrophobicContact CG-CD1 4.27Å; Q639-I641 HydrophobicContact CG-CG1 3.93Å; I641-Q679 VanDerWaalsContact CG2-CD 3.42Å; I641-Q679 HydrophobicContact CG2-CG 3.5Å; I641-Q679 VanDerWaalsContact CG2-CG 3.5Å; I641-A680 WeakPolarHBondContact CA-O 3.41Å
642F94.2Very high94.9Very high3 Ų345 Ų451%0.01325%0.25CS..EExtended strand (participates in β ladder)trans-142.9139.5175.5173.7-101.4000110.6P620 I622 L674 Q679 A680 M700 F705 I708P620-F642 HydrophobicContact CG-CE2 3.98Å; P620-F642 HydrophobicContact CG-CZ 4.41Å; I622-F642 HydrophobicContact CG1-CD2 4.07Å; F642-L674 HydrophobicContact CD1-CD1 3.77Å; F642-L674 HydrophobicContact CE1-CD1 3.89Å; F642-Q679 CarbonylContact O-C 3.46Å; F642-Q679 WeakPolarHBondContact O-CA 3.37Å; F642-A680 PolarHBondContact N-O 3.37Å; F642-A680 PolarHBondContact O-N 2.85Å; F642-M700 HydrophobicContact CB-CE 3.8Å; F642-M700 HydrophobicContact CD1-CE 3.82Å; F642-M700 HydrophobicContact CD1-CG 4.2Å; F642-M700 HydrophobicContact CE1-CG 4.25Å; F642-M700 HydrophobicContact CG-CE 3.88Å; F642-M700 HydrophobicContact CG-CG 4.45Å; F642-F705 HydrophobicContact CE1-CE2 4.1Å; F642-F705 AromaticContact CE1-CZ 3.63Å; F642-F705 HydrophobicContact CE1-CZ 3.63Å; F642-F705 HydrophobicContact CZ-CE1 4.23Å; F642-F705 AromaticContact CZ-CE2 3.87Å; F642-F705 HydrophobicContact CZ-CE2 3.87Å; F642-F705 AromaticContact CZ-CZ 3.53Å; F642-F705 HydrophobicContact CZ-CZ 3.53Å; F642-I708 HydrophobicContact CE2-CB 4.45Å; F642-I708 HydrophobicContact CE2-CD1 3.35Å; F642-I708 HydrophobicContact CE2-CG1 4.47Å; F642-I708 HydrophobicContact CE2-CG2 4.08Å; F642-I708 HydrophobicContact CZ-CD1 3.45Å; F642-I708 VanDerWaalsContact CZ-CD1 3.45Å
643S92.1Very high94.8Very high37 Ų3744.2 Ų44.226%0.25925%0.245SC..EExtended strand (participates in β ladder)trans-113.8131.5176.7-61.80000110.8P620 P645 H678 Q679P620-S643 WeakPolarHBondContact CG-O 3.43Å; S643-P645 VanDerWaalsContact O-CD 3.28Å; S643-P645 WeakPolarHBondContact O-CD 3.45Å; S643-H678 WeakPolarHBondContact CA-O 3.21Å; S643-Q679 PolarHBondContact OG-NE2 3.47Å
644N93.4Very high94.7Very high0 Ų039.2 Ų39.20%022%0.219CC..  trans-65.9114170.917413.4000109.6L646 E648 V650 L674 K675 Q677 H678N644-L646 PolarHBondContact O-N 2.92Å; N644-L646 WeakPolarHBondContact OD1-CB 3.07Å; N644-L646 PolarHBondContact OD1-N 3.42Å; N644-E648 PolarHBondContact ND2-O 3.21Å; N644-V650 VanDerWaalsContact OD1-CG2 3.28Å; N644-V650 WeakPolarHBondContact OD1-CG2 3.36Å; N644-L674 HydrophobicContact CB-CB 4.23Å; N644-L674 PolarHBondContact ND2-O 2.99Å; N644-K675 PolarHBondContact ND2-O 2.9Å; N644-Q677 VanDerWaalsContact O-CA 3.23Å; N644-Q677 WeakPolarHBondContact O-CA 3.38Å; N644-Q677 PolarHBondContact O-N 2.84Å; N644-H678 PolarHBondContact N-O 3.41Å
645P89.1Confident94.7Very high27 Ų2735 Ų3518%0.17520%0.199CC..  trans-76.7-12.8-178.431.6-33.5000113.3P620 S643 Q677P620-P645 HydrophobicContact CG-CB 3.72Å; P620-P645 HydrophobicContact CG-CG 3.65Å; S643-P645 VanDerWaalsContact O-CD 3.28Å; S643-P645 WeakPolarHBondContact O-CD 3.45Å; P645-Q677 PolarHBondContact O-NE2 2.94Å
646L91.9Very high94.7Very high0 Ų030.5 Ų30.50%017%0.17CC..SBendtrans-85.6152.4-170.9-52.9-177.6000111.5M519 Y581 N644 E648 V650 P676 Q677 K704M519-L646 HydrophobicContact CE-CD2 4.43Å; M519-L646 HydrophobicContact CG-CD2 4.05Å; Y581-L646 HydrophobicContact CE2-CD2 4.18Å; N644-L646 PolarHBondContact O-N 2.92Å; N644-L646 WeakPolarHBondContact OD1-CB 3.07Å; N644-L646 PolarHBondContact OD1-N 3.42Å; L646-E648 HydrophobicContact CB-CG 4.02Å; L646-E648 HydrophobicContact CD1-CG 4.18Å; L646-E648 PolarHBondContact O-N 2.87Å; L646-V650 HydrophobicContact CD1-CG2 3.85Å; L646-V650 HydrophobicContact CG-CG2 4.44Å; L646-P676 WeakPolarHBondContact O-CA 3.44Å; L646-Q677 PolarHBondContact O-N 2.76Å; L646-Q677 PolarHBondContact O-NE2 2.98Å; L646-K704 HydrophobicContact CD1-CB 3.87Å; L646-K704 HydrophobicContact CD1-CG 4.02Å
647S90.8Very high94.7Very high99 Ų9930.3 Ų30.369%0.69217%0.169SC*.SBendtrans-79.33.5169.4-56.20000112.7
648E91.4Very high94.6Very high64 Ų6428.9 Ų28.930%0.29916%0.158SC..SBendtrans-121.7164.2175.162.1173.4145.800111.3Y581 N644 L646 K704Y581-E648 WeakPolarHBondContact CE1-OE1 3.27Å; Y581-E648 PolarHBondContact OH-OE1 3.11Å; Y581-E648 VanDerWaalsContact OH-OE1 3.13Å; N644-E648 PolarHBondContact ND2-O 3.21Å; L646-E648 HydrophobicContact CB-CG 4.02Å; L646-E648 HydrophobicContact CD1-CG 4.18Å; L646-E648 PolarHBondContact O-N 2.87Å; E648-K704 IonicContact OE1-NZ 2.81Å; E648-K704 PolarHBondContact OE1-NZ 3.45Å; E648-K704 WeakPolarHBondContact OE2-CE 3.31Å; E648-K704 IonicContact OE2-NZ 3.16Å; E648-K704 PolarHBondContact OE2-NZ 2.67Å
649Q94.6Very high94.6Very high98 Ų9829 Ų2946%0.45816%0.159SC..  trans-71.4150.9177.475.3-174.52100111.2E651 V673 L674Q649-E651 PolarHBondContact NE2-OE1 2.77Å; Q649-V673 HydrophobicContact CB-CG1 4.37Å; Q649-L674 WeakPolarHBondContact CA-O 3.48Å
650V93.4Very high94.6Very high0 Ų027.1 Ų27.10%015%0.151CC..EExtended strand (participates in β ladder)trans-121.1131.9177.6179.60000108.6N644 L646 V673 L674 S702 K704 F705N644-V650 VanDerWaalsContact OD1-CG2 3.28Å; N644-V650 WeakPolarHBondContact OD1-CG2 3.36Å; L646-V650 HydrophobicContact CD1-CG2 3.85Å; L646-V650 HydrophobicContact CG-CG2 4.44Å; V650-V673 CarbonylContact O-C 3.56Å; V650-V673 WeakPolarHBondContact O-CA 3.45Å; V650-L674 PolarHBondContact N-O 3.4Å; V650-L674 PolarHBondContact O-N 3.12Å; V650-S702 WeakPolarHBondContact CG1-OG 3.41Å; V650-K704 HydrophobicContact CG1-CB 4.37Å; V650-K704 HydrophobicContact CG2-CB 4.36Å; V650-K704 HydrophobicContact CG2-CG 4.28Å; V650-F705 HydrophobicContact CB-CE1 4.37Å; V650-F705 HydrophobicContact CG1-CE1 3.72Å; V650-F705 HydrophobicContact CG1-CZ 3.69Å; V650-F705 HydrophobicContact CG2-CE1 3.89Å; V650-F705 HydrophobicContact CG2-CZ 4.46Å
651E94.9Very high94.5Very high73 Ų7327 Ų2734%0.34115%0.15SC..EExtended strand (participates in β ladder)trans-115.7170.1-173.2-56.9175-167.900110.7Q649 C653 G672 V673 S702 N703Q649-E651 PolarHBondContact NE2-OE1 2.77Å; E651-C653 PolarHBondContact O-N 2.89Å; E651-C653 VanDerWaalsContact O-N 3.15Å; E651-G672 CarbonylContact C-O 3.54Å; E651-V673 HydrophobicContact CG-CG1 4.36Å; E651-V673 HydrophobicContact CG-CG2 4.15Å; E651-S702 WeakPolarHBondContact O-CB 3.43Å; E651-N703 PolarHBondContact N-OD1 3.48Å; E651-N703 PolarHBondContact O-N 2.59Å; E651-N703 PolarHBondContact O-OD1 2.88Å
652D94.6Very high94.6Very high97 Ų9725.9 Ų25.952%0.51915%0.145SC..EExtended strand (participates in β ladder)trans53.633.3-179.6-54.8-40.7000113.7V654 G672D652-V654 PolarHBondContact O-N 3.21Å; D652-G672 PolarHBondContact N-O 3.2Å
653C95.1Very high94.6Very high0 Ų026 Ų260%015%0.145CC..EExtended strand (participates in β ladder)trans-66.9117.8-178.9-640000110.1E651 L671 G672 L674 M700 R701E651-C653 PolarHBondContact O-N 2.89Å; E651-C653 VanDerWaalsContact O-N 3.15Å; C653-L671 HydrophobicContact CB-CB 3.81Å; C653-L671 PolarHBondContact O-N 3.11Å; C653-G672 WeakPolarHBondContact CB-O 3.48Å; C653-G672 PolarHBondContact N-O 2.86Å; C653-G672 PolarHBondContact O-N 2.87Å; C653-L674 HydrophobicContact CB-CD1 4.39Å; C653-L674 HydrophobicContact CB-CG 4.38Å; C653-M700 HydrophobicContact CB-SD 4.4Å; C653-R701 WeakPolarHBondContact CA-O 3.13Å
654V95.6Very high94.6Very high17 Ų1730.8 Ų30.810%0.10316%0.161CC..EExtended strand (participates in β ladder)trans-127123.9174.5179.90000109.5D652 V669 L670 R701D652-V654 PolarHBondContact O-N 3.21Å; V654-V669 WeakPolarHBondContact CA-O 3.26Å; V654-L670 HydrophobicContact CG2-CD1 3.82Å; V654-R701 HydrophobicContact CB-CG 3.86Å; V654-R701 PolarHBondContact N-O 3.08Å; V654-R701 PolarHBondContact O-N 3.18Å
655L95.9Very high94.5Very high0 Ų038.1 Ų38.10%019%0.193CC..EExtended strand (participates in β ladder)trans-95.7125.3172.6176.870000109.4I622 V640 V657 K668 V669 L671 I682 A698 N699 M700I622-L655 HydrophobicContact CD1-CD1 4.41Å; V640-L655 HydrophobicContact CB-CD2 3.92Å; V640-L655 HydrophobicContact CG1-CD1 3.97Å; V640-L655 HydrophobicContact CG1-CD2 3.74Å; V640-L655 HydrophobicContact CG2-CD2 4.36Å; L655-V657 HydrophobicContact CD1-CG2 4.23Å; L655-V657 HydrophobicContact CD2-CG2 3.96Å; L655-V657 HydrophobicContact CG-CG2 3.86Å; L655-K668 CarbonylContact O-C 3.45Å; L655-K668 WeakPolarHBondContact O-CA 3.49Å; L655-V669 HydrophobicContact CB-CB 4.32Å; L655-V669 PolarHBondContact N-O 3.23Å; L655-V669 PolarHBondContact O-N 3.39Å; L655-L671 HydrophobicContact CB-CD1 4.25Å; L655-I682 HydrophobicContact CD2-CD1 3.67Å; L655-A698 HydrophobicContact CD1-CB 4.19Å; L655-N699 CarbonylContact C-O 3.47Å; L655-N699 WeakPolarHBondContact CA-O 3.45Å; L655-M700 HydrophobicContact CB-CE 4.07Å; L655-M700 HydrophobicContact CB-SD 4.25Å; L655-M700 HydrophobicContact CD1-CE 4.05Å
656T96.4Very high94.7Very high11 Ų1139 Ų397%0.06720%0.195CC..EExtended strand (participates in β ladder)trans-109.1130.9170.4-57.20000109.1Q666 Q667 K668 A698 N699T656-Q666 HydrophobicContact CG2-CB 4.37Å; T656-Q667 CarbonylContact C-O 3.56Å; T656-Q667 VanDerWaalsContact CA-O 3.27Å; T656-Q667 WeakPolarHBondContact CA-O 3.36Å; T656-K668 HydrophobicContact CG2-CG 4.28Å; T656-A698 CarbonylContact O-C 3.49Å; T656-A698 VanDerWaalsContact O-CA 3.25Å; T656-A698 WeakPolarHBondContact O-CA 3.2Å; T656-N699 PolarHBondContact N-O 2.72Å; T656-N699 PolarHBondContact O-N 2.93Å
657V97.2Very high94.9Very high0 Ų042 Ų420%021%0.209CC..EExtended strand (participates in β ladder)trans-129.1136.2178.2-174.90000110.4V640 L655 F663 Q667 L684 I696 Q697 A698V640-V657 HydrophobicContact CG2-CG2 4.3Å; L655-V657 HydrophobicContact CD1-CG2 4.23Å; L655-V657 HydrophobicContact CD2-CG2 3.96Å; L655-V657 HydrophobicContact CG-CG2 3.86Å; V657-F663 HydrophobicContact CG1-CE2 3.99Å; V657-F663 HydrophobicContact CG1-CZ 3.82Å; V657-Q667 PolarHBondContact N-O 2.88Å; V657-Q667 PolarHBondContact O-N 3.46Å; V657-L684 HydrophobicContact CB-CD1 3.94Å; V657-L684 HydrophobicContact CG1-CD1 4.26Å; V657-L684 HydrophobicContact CG2-CD1 3.6Å; V657-I696 HydrophobicContact CG1-CG2 3.75Å; V657-Q697 VanDerWaalsContact CA-O 3.31Å; V657-Q697 WeakPolarHBondContact CA-O 3.36Å; V657-A698 HydrophobicContact CG2-CB 4.28Å
658E97.3Very high95.1Very high9 Ų944.4 Ų44.44%0.04221%0.207CC..EExtended strand (participates in β ladder)trans-151.3175175.272.5174.7108.400112.9N182 T256 Q666 Q697N182-E658 HydrophobicContact CB-CG 4.4Å; N182-E658 PolarHBondContact ND2-OE2 2.92Å; T256-E658 WeakPolarHBondContact CB-OE1 3.43Å; T256-E658 PolarHBondContact OG1-OE1 2.81Å; E658-Q666 HydrophobicContact CB-CG 3.97Å; E658-Q666 PolarHBondContact OE1-NE2 2.96Å; E658-Q697 PolarHBondContact N-O 3Å; E658-Q697 PolarHBondContact O-N 3.04Å
659G97.2Very high95.3Very high3 Ų343 Ų433%0.03120%0.202CC..  trans170.2124.9174.900000110.5L662 F663 Q695G659-L662 WeakPolarHBondContact O-CB 3.4Å; G659-L662 PolarHBondContact O-N 2.92Å; G659-L662 VanDerWaalsContact O-N 3.08Å; G659-F663 PolarHBondContact O-N 2.93Å; G659-Q695 VanDerWaalsContact CA-O 3.3Å; G659-Q695 WeakPolarHBondContact CA-O 3.19Å
660S97.2Very high95.3Very high5 Ų544.8 Ų44.84%0.03521%0.214CC..THydrogen-bonded Turntrans-59.9140.7178.9-67.30000111D164 N182 G184 E187 L662 R694D164-S660 WeakPolarHBondContact OD2-CB 3.49Å; N182-S660 PolarHBondContact ND2-OG 3.1Å; N182-S660 PolarHBondContact OD1-OG 2.95Å; G184-S660 VanDerWaalsContact CA-OG 3.23Å; G184-S660 WeakPolarHBondContact CA-OG 3.38Å; E187-S660 WeakPolarHBondContact CG-OG 3.15Å; E187-S660 VanDerWaalsContact OE1-CA 3.24Å; E187-S660 WeakPolarHBondContact OE1-CA 3.19Å; E187-S660 VanDerWaalsContact OE1-CB 3.29Å; E187-S660 WeakPolarHBondContact OE1-CB 3.22Å; S660-L662 PolarHBondContact O-N 2.88Å; S660-R694 WeakPolarHBondContact O-CD 3.49Å
661G95.9Very high95.3Very high0 Ų046.8 Ų46.80%023%0.225CC..THydrogen-bonded Turntrans68.5-11.3-172.500000116.6E187 P688 F689 K690E187-G661 PolarHBondContact OE1-N 2.75Å; G661-P688 CarbonylContact O-C 3.57Å; G661-P688 WeakPolarHBondContact O-CA 3.23Å; G661-F689 WeakPolarHBondContact O-CD1 3.49Å; G661-F689 PolarHBondContact O-N 2.91Å; G661-K690 PolarHBondContact O-N 2.94Å
662L97.5Very high95.2Very high0 Ų044.4 Ų44.40%022%0.22CC..THydrogen-bonded Turntrans-104.9-39.8-179-61.9175.9000112.2G659 S660 T686 P688 R694 I696 V716G659-L662 WeakPolarHBondContact O-CB 3.4Å; G659-L662 PolarHBondContact O-N 2.92Å; G659-L662 VanDerWaalsContact O-N 3.08Å; S660-L662 PolarHBondContact O-N 2.88Å; L662-T686 PolarHBondContact O-OG1 3.28Å; L662-P688 HydrophobicContact CD2-CB 4Å; L662-P688 HydrophobicContact CD2-CG 4.02Å; L662-R694 HydrophobicContact CD1-CB 3.82Å; L662-R694 HydrophobicContact CD2-CB 4.06Å; L662-R694 HydrophobicContact CD2-CG 4.31Å; L662-R694 HydrophobicContact CG-CB 3.84Å; L662-R694 HydrophobicContact CG-CG 4.32Å; L662-I696 HydrophobicContact CD1-CD1 4.49Å; L662-I696 HydrophobicContact CD1-CG1 3.48Å; L662-I696 VanDerWaalsContact CD1-CG1 3.48Å; L662-V716 HydrophobicContact CD2-CG2 3.63Å
663F96.1Very high95.2Very high7 Ų743.7 Ų43.73%0.03122%0.219CC..  trans-128.3129-179-62.9-91.4000110.6I638 V657 G659 K665 Q667 T686 I696I638-F663 HydrophobicContact CD1-CE2 4.07Å; I638-F663 HydrophobicContact CD1-CZ 3.57Å; V657-F663 HydrophobicContact CG1-CE2 3.99Å; V657-F663 HydrophobicContact CG1-CZ 3.82Å; G659-F663 PolarHBondContact O-N 2.93Å; F663-K665 PolarHBondContact O-N 2.92Å; F663-Q667 HydrophobicContact CD1-CG 3.68Å; F663-Q667 HydrophobicContact CE1-CG 3.89Å; F663-T686 HydrophobicContact CD1-CG2 4.47Å; F663-T686 WeakPolarHBondContact CD1-OG1 3.28Å; F663-T686 HydrophobicContact CE1-CG2 4.06Å; F663-T686 HydrophobicContact CE2-CG2 4.48Å; F663-T686 HydrophobicContact CZ-CG2 4.07Å; F663-I696 HydrophobicContact CE2-CG2 4.25Å
664K90.8Very high95.2Very high136 Ų13644.1 Ų44.159%0.59122%0.221SC*.SBendtrans-68.1-23.8176.3-66.7-68.1-176.3-1720113.6F689K664-F689 HydrophobicContact CD-CD1 3.81Å; K664-F689 HydrophobicContact CD-CE1 3.51Å; K664-F689 HydrophobicContact CD-CE2 4.27Å; K664-F689 HydrophobicContact CD-CG 4.31Å; K664-F689 HydrophobicContact CD-CZ 3.76Å; K664-F689 VanDerWaalsContact CE-CG 3.48Å; K664-F689 HydrophobicContact CG-CD1 4.22Å; K664-F689 HydrophobicContact CG-CE1 3.95Å; K664-F689 VanDerWaalsContact NZ-CE2 3.32Å
665K90.9Very high95.2Very high154 Ų15450.3 Ų50.367%0.6725%0.247SC*.SBendtrans-151.5155.4178.365.2-177.4-178.8-179.60109.9F663 Q667F663-K665 PolarHBondContact O-N 2.92Å; K665-Q667 PolarHBondContact O-N 2.88Å; K665-Q667 PolarHBondContact O-NE2 2.9Å
666Q93.9Very high95.1Very high47 Ų4753.3 Ų53.322%0.2227%0.267CS..  trans-55.3132.5171.4-68.3-175.6-18.300110.5T656 E658T656-Q666 HydrophobicContact CG2-CB 4.37Å; E658-Q666 HydrophobicContact CB-CG 3.97Å; E658-Q666 PolarHBondContact OE1-NE2 2.96Å
667Q95.4Very high94.8Very high62 Ų6258.5 Ų58.529%0.2929%0.29SS..EExtended strand (participates in β ladder)trans-94128.8171.7-57.3-53.9-4900108.8T656 V657 F663 K665T656-Q667 CarbonylContact C-O 3.56Å; T656-Q667 VanDerWaalsContact CA-O 3.27Å; T656-Q667 WeakPolarHBondContact CA-O 3.36Å; V657-Q667 PolarHBondContact N-O 2.88Å; V657-Q667 PolarHBondContact O-N 3.46Å; F663-Q667 HydrophobicContact CD1-CG 3.68Å; F663-Q667 HydrophobicContact CE1-CG 3.89Å; K665-Q667 PolarHBondContact O-N 2.88Å; K665-Q667 PolarHBondContact O-NE2 2.9Å
668K95.4Very high94.6Very high150 Ų15063.1 Ų63.165%0.65231%0.311SS*.EExtended strand (participates in β ladder)trans-118.5124.5175.3-67.4-173.4179-176.50109.3L655 T656L655-K668 CarbonylContact O-C 3.45Å; L655-K668 WeakPolarHBondContact O-CA 3.49Å; T656-K668 HydrophobicContact CG2-CG 4.28Å
669V95.5Very high94.3Very high33 Ų3368 Ų6820%0.233%0.334CS..EExtended strand (participates in β ladder)trans-118.6121.9-178.8-171.90000108.8V654 L655 L671 I682 L684V654-V669 WeakPolarHBondContact CA-O 3.26Å; L655-V669 HydrophobicContact CB-CB 4.32Å; L655-V669 PolarHBondContact N-O 3.23Å; L655-V669 PolarHBondContact O-N 3.39Å; V669-L671 HydrophobicContact CG1-CD2 3.81Å; V669-I682 HydrophobicContact CG1-CG2 4.37Å; V669-L684 HydrophobicContact CG2-CD2 3.77Å
670L95.2Very high94.1Very high136 Ų13668.3 Ų68.371%0.71234%0.336SS*.EExtended strand (participates in β ladder)trans-83.5116172.9-179.365.2000109.3V654V654-L670 HydrophobicContact CG2-CD1 3.82Å
671L92.9Very high94Very high42 Ų4271.1 Ų71.122%0.2236%0.356CS..EExtended strand (participates in β ladder)trans-96.2-19.6176.7-54.6179000112.5C653 L655 V669 V673 I682 M700C653-L671 HydrophobicContact CB-CB 3.81Å; C653-L671 PolarHBondContact O-N 3.11Å; L655-L671 HydrophobicContact CB-CD1 4.25Å; V669-L671 HydrophobicContact CG1-CD2 3.81Å; L671-V673 PolarHBondContact O-N 3.26Å; L671-I682 HydrophobicContact CD1-CD1 3.63Å; L671-I682 HydrophobicContact CD2-CD1 3.28Å; L671-I682 HydrophobicContact CD2-CG1 3.62Å; L671-I682 HydrophobicContact CG-CD1 4.05Å; L671-M700 HydrophobicContact CD1-CE 3.45Å; L671-M700 VanDerWaalsContact CD1-CE 3.45Å; L671-M700 HydrophobicContact CD1-SD 3.9Å
672G92.8Very high94.1Very high24 Ų2472.4 Ų72.425%0.24736%0.363CS..EExtended strand (participates in β ladder)trans72.7-108.9-18000000111.4E651 D652 C653E651-G672 CarbonylContact C-O 3.54Å; D652-G672 PolarHBondContact N-O 3.2Å; C653-G672 WeakPolarHBondContact CB-O 3.48Å; C653-G672 PolarHBondContact N-O 2.86Å; C653-G672 PolarHBondContact O-N 2.87Å
673V95.6Very high94Very high82 Ų8277.4 Ų77.450%0.49739%0.389SS..EExtended strand (participates in β ladder)trans-111.9129.2-171.6-175.50000111.3Q649 V650 E651 L671Q649-V673 HydrophobicContact CB-CG1 4.37Å; V650-V673 CarbonylContact O-C 3.56Å; V650-V673 WeakPolarHBondContact O-CA 3.45Å; E651-V673 HydrophobicContact CG-CG1 4.36Å; E651-V673 HydrophobicContact CG-CG2 4.15Å; L671-V673 PolarHBondContact O-N 3.26Å
674L94.4Very high94Very high8 Ų878.2 Ų78.24%0.04239%0.393CS..EExtended strand (participates in β ladder)trans-106.7122.3170.6-64.1178.1000110.1F642 N644 Q649 V650 C653 A680F642-L674 HydrophobicContact CD1-CD1 3.77Å; F642-L674 HydrophobicContact CE1-CD1 3.89Å; N644-L674 HydrophobicContact CB-CB 4.23Å; N644-L674 PolarHBondContact ND2-O 2.99Å; Q649-L674 WeakPolarHBondContact CA-O 3.48Å; V650-L674 PolarHBondContact N-O 3.4Å; V650-L674 PolarHBondContact O-N 3.12Å; C653-L674 HydrophobicContact CB-CD1 4.39Å; C653-L674 HydrophobicContact CB-CG 4.38Å; L674-A680 HydrophobicContact CD1-CB 4.49Å; L674-A680 HydrophobicContact CD2-CB 3.62Å
675K95.4Very high94.3Very high148 Ų14879 Ų7964%0.64340%0.399SS*.  trans-64159.4176-69.8-178.5-178178.80111.4N644 Q677 H678N644-K675 PolarHBondContact ND2-O 2.9Å; K675-Q677 PolarHBondContact O-N 2.86Å; K675-H678 HydrophobicContact CB-CB 3.93Å; K675-H678 VanDerWaalsContact O-CB 3.31Å; K675-H678 WeakPolarHBondContact O-CB 3.46Å; K675-H678 PolarHBondContact O-N 2.98Å; K675-H678 VanDerWaalsContact O-N 3.12Å
676P94.2Very high94.5Very high63 Ų6372.5 Ų72.541%0.40937%0.372SS..THydrogen-bonded Turntrans-49.5131.9173.5-26.132.6000111.8L646 H678L646-P676 WeakPolarHBondContact O-CA 3.44Å; P676-H678 PolarHBondContact O-N 3.01Å
677Q89.9Confident94.7Very high119 Ų11973.7 Ų73.756%0.55638%0.382SS*.THydrogen-bonded Turntrans56.711.7178.2-54-61.3-25.400115.6N644 P645 L646 K675N644-Q677 VanDerWaalsContact O-CA 3.23Å; N644-Q677 WeakPolarHBondContact O-CA 3.38Å; N644-Q677 PolarHBondContact O-N 2.84Å; P645-Q677 PolarHBondContact O-NE2 2.94Å; L646-Q677 PolarHBondContact O-N 2.76Å; L646-Q677 PolarHBondContact O-NE2 2.98Å; K675-Q677 PolarHBondContact O-N 2.86Å
678H92.1Very high94.8Very high97 Ų9770.7 Ų70.745%0.44937%0.368SS..PPolyproline II helixtrans-79.4143.2-179.7-175.265.7000111.4S643 N644 K675 P676S643-H678 WeakPolarHBondContact CA-O 3.21Å; N644-H678 PolarHBondContact N-O 3.41Å; K675-H678 HydrophobicContact CB-CB 3.93Å; K675-H678 VanDerWaalsContact O-CB 3.31Å; K675-H678 WeakPolarHBondContact O-CB 3.46Å; K675-H678 PolarHBondContact O-N 2.98Å; K675-H678 VanDerWaalsContact O-N 3.12Å; P676-H678 PolarHBondContact O-N 3.01Å
679Q92.9Very high94.8Very high111 Ų11165.5 Ų65.552%0.51935%0.346SS..EExtended strand (participates in β ladder)trans-101.8120.5175-178.1174.184.500110.3I641 F642 S643I641-Q679 VanDerWaalsContact CG2-CD 3.42Å; I641-Q679 HydrophobicContact CG2-CG 3.5Å; I641-Q679 VanDerWaalsContact CG2-CG 3.5Å; F642-Q679 CarbonylContact O-C 3.46Å; F642-Q679 WeakPolarHBondContact O-CA 3.37Å; S643-Q679 PolarHBondContact OG-NE2 3.47Å
680A92.8Very high94.7Very high10 Ų1065.2 Ų65.28%0.08334%0.342CS..EExtended strand (participates in β ladder)trans-88138.6169.200000110I641 F642 L674I641-A680 WeakPolarHBondContact CA-O 3.41Å; F642-A680 PolarHBondContact N-O 3.37Å; F642-A680 PolarHBondContact O-N 2.85Å; L674-A680 HydrophobicContact CD1-CB 4.49Å; L674-A680 HydrophobicContact CD2-CB 3.62Å
681S95.4Very high94.7Very high65 Ų6559.9 Ų59.946%0.45532%0.316SS..EExtended strand (participates in β ladder)trans-133.6123.5173.3-172.10000109.2Q639 V640Q639-S681 PolarHBondContact NE2-OG 2.94Å; V640-S681 WeakPolarHBondContact O-CA 3.3Å
682I95.9Very high94.8Very high27 Ų2758.7 Ų58.714%0.13831%0.313CS..EExtended strand (participates in β ladder)trans-125.1138.3-176.6-56.8126.9000108.6Q639 V640 L655 V669 L671 L684Q639-I682 CarbonylContact C-O 3.59Å; Q639-I682 VanDerWaalsContact CA-O 3.29Å; Q639-I682 WeakPolarHBondContact CA-O 3.34Å; V640-I682 PolarHBondContact N-O 2.87Å; V640-I682 PolarHBondContact O-N 2.89Å; L655-I682 HydrophobicContact CD2-CD1 3.67Å; V669-I682 HydrophobicContact CG1-CG2 4.37Å; L671-I682 HydrophobicContact CD1-CD1 3.63Å; L671-I682 HydrophobicContact CD2-CD1 3.28Å; L671-I682 HydrophobicContact CD2-CG1 3.62Å; L671-I682 HydrophobicContact CG-CD1 4.05Å; I682-L684 HydrophobicContact CG2-CD2 4.14Å; I682-L684 HydrophobicContact CG2-CG 4.3Å
683I96.8Very high94.9Very high105 Ų10561.3 Ų61.354%0.53832%0.319SS..EExtended strand (participates in β ladder)trans-103.8129.4171.3-60.4175.9000108.4L627 I638L627-I683 HydrophobicContact CD1-CD1 4.45Å; I638-I683 CarbonylContact O-C 3.09Å; I638-I683 WeakPolarHBondContact O-CA 3.28Å
684L96.3Very high95Very high23 Ų2358.3 Ų58.312%0.1230%0.299CS..EExtended strand (participates in β ladder)trans-118.4142.8174.6-63175.7000109.3S637 I638 V640 V657 V669 I682S637-L684 CarbonylContact C-O 3.58Å; S637-L684 WeakPolarHBondContact CA-O 3.32Å; I638-L684 PolarHBondContact N-O 2.77Å; I638-L684 PolarHBondContact O-N 2.67Å; V640-L684 HydrophobicContact CG2-CD1 4.39Å; V657-L684 HydrophobicContact CB-CD1 3.94Å; V657-L684 HydrophobicContact CG1-CD1 4.26Å; V657-L684 HydrophobicContact CG2-CD1 3.6Å; V669-L684 HydrophobicContact CG2-CD2 3.77Å; I682-L684 HydrophobicContact CG2-CD2 4.14Å; I682-L684 HydrophobicContact CG2-CG 4.3Å
685E95.8Very high95.1Very high153 Ų15358 Ų5872%0.71530%0.298SS*.EExtended strand (participates in β ladder)trans-106.3141.4173-65.1-174.8167.400110L636L636-E685 WeakPolarHBondContact O-CA 3.37Å
686T96.6Very high95.2Very high18 Ų1851 Ų5111%0.1127%0.267CS..EExtended strand (participates in β ladder)trans-144.5168.8171.1-160.80000111.3P635 L636 I638 L662 F663P635-T686 CarbonylContact C-O 3.55Å; L636-T686 HydrophobicContact CB-CG2 4.19Å; L636-T686 HydrophobicContact CD2-CG2 4.45Å; L636-T686 PolarHBondContact N-O 2.91Å; L636-T686 PolarHBondContact O-N 2.9Å; I638-T686 HydrophobicContact CD1-CG2 3.77Å; L662-T686 PolarHBondContact O-OG1 3.28Å; F663-T686 HydrophobicContact CD1-CG2 4.47Å; F663-T686 WeakPolarHBondContact CD1-OG1 3.28Å; F663-T686 HydrophobicContact CE1-CG2 4.06Å; F663-T686 HydrophobicContact CE2-CG2 4.48Å; F663-T686 HydrophobicContact CZ-CG2 4.07Å
687V97.3Very high95.4Very high71 Ų7148.1 Ų48.143%0.4325%0.248SC..  trans-125.6101.1174.5-177.90000107.8F689V687-F689 PolarHBondContact O-N 2.75Å
688P97.3Very high95.7Very high0 Ų042.4 Ų42.40%022%0.222CC..  trans-56.6136.7174.9-2536.2000110.9N633 Q634 L636 G661 L662 V716N633-P688 PolarHBondContact N-O 3.12Å; Q634-P688 VanDerWaalsContact O-CD 3.27Å; Q634-P688 WeakPolarHBondContact O-CD 3.31Å; L636-P688 HydrophobicContact CB-CG 4.18Å; L636-P688 HydrophobicContact CD2-CG 3.95Å; G661-P688 CarbonylContact O-C 3.57Å; G661-P688 WeakPolarHBondContact O-CA 3.23Å; L662-P688 HydrophobicContact CD2-CB 4Å; L662-P688 HydrophobicContact CD2-CG 4.02Å; P688-V716 HydrophobicContact CB-CG1 3.65Å; P688-V716 HydrophobicContact CB-CG2 4.25Å; P688-V716 HydrophobicContact CG-CG1 4.4Å
689F95.1Very high95.8Very high41 Ų4137.8 Ų37.818%0.1820%0.2CC..  trans-125.23.2-177.558.6-91000113G661 K664 V687G661-F689 WeakPolarHBondContact O-CD1 3.49Å; G661-F689 PolarHBondContact O-N 2.91Å; K664-F689 HydrophobicContact CD-CD1 3.81Å; K664-F689 HydrophobicContact CD-CE1 3.51Å; K664-F689 HydrophobicContact CD-CE2 4.27Å; K664-F689 HydrophobicContact CD-CG 4.31Å; K664-F689 HydrophobicContact CD-CZ 3.76Å; K664-F689 VanDerWaalsContact CE-CG 3.48Å; K664-F689 HydrophobicContact CG-CD1 4.22Å; K664-F689 HydrophobicContact CG-CE1 3.95Å; K664-F689 VanDerWaalsContact NZ-CE2 3.32Å; V687-F689 PolarHBondContact O-N 2.75Å
690K93.9Very high95.9Very high27 Ų2732.5 Ų32.512%0.11718%0.175CC..SBendtrans-134.6139.8170.5-59.8-179160.5-155.40110.1E25 F186 G661 R694 V716E25-K690 PolarHBondContact O-NZ 2.91Å; E25-K690 WeakPolarHBondContact OE2-CD 3.45Å; E25-K690 WeakPolarHBondContact OE2-CE 3.16Å; E25-K690 IonicContact OE2-NZ 2.72Å; E25-K690 PolarHBondContact OE2-NZ 2.83Å; F186-K690 PolarHBondContact O-NZ 2.57Å; G661-K690 PolarHBondContact O-N 2.94Å; K690-R694 VanDerWaalsContact CB-NH2 3.35Å; K690-V716 WeakPolarHBondContact O-CG1 3.22Å
691S94.7Very high95.9Very high24 Ų2436.3 Ų36.317%0.16819%0.188CC..  trans-83.9167.4179.454.30000113R694 V716 F718S691-R694 PolarHBondContact O-NH1 2.75Å; S691-R694 PolarHBondContact O-NH2 3.47Å; S691-V716 CarbonylContact C-O 3.48Å; S691-V716 WeakPolarHBondContact CA-O 3.36Å; S691-F718 WeakPolarHBondContact OG-CE2 3.46Å; S691-F718 WeakPolarHBondContact OG-CZ 3.43Å
692G95Very high95.8Very high16 Ų1633.6 Ų33.617%0.16517%0.169CC..EExtended strand (participates in β ladder)trans91.8-165.4174.900000113.1R694 V716G692-R694 PolarHBondContact O-N 3.27Å; G692-V716 PolarHBondContact N-O 3.41Å; G692-V716 PolarHBondContact O-N 3.06Å
693Q95.8Very high95.5Very high79 Ų7934.9 Ų34.937%0.36918%0.176SC..EExtended strand (participates in β ladder)trans-69.9126.1-178.3-172.572.5600110.7Y165 Y715Y165-Q693 HydrophobicContact CE1-CG 4.43Å; Y165-Q693 WeakPolarHBondContact OH-CG 3.35Å; Q693-Y715 HydrophobicContact CB-CD2 4.43Å
694R96.6Very high95Very high19 Ų1933.3 Ų33.37%0.07217%0.165CC..EExtended strand (participates in β ladder)trans-134.6167178.3-58.6-61.7178.8-110.415.3110.3E25 S660 L662 K690 S691 G692 N713 V714 V716E25-R694 IonicContact OE1-NH2 3.3Å; E25-R694 PolarHBondContact OE1-NH2 2.91Å; E25-R694 IonicContact OE2-NH2 3.4Å; E25-R694 PolarHBondContact OE2-NH2 2.98Å; S660-R694 WeakPolarHBondContact O-CD 3.49Å; L662-R694 HydrophobicContact CD1-CB 3.82Å; L662-R694 HydrophobicContact CD2-CB 4.06Å; L662-R694 HydrophobicContact CD2-CG 4.31Å; L662-R694 HydrophobicContact CG-CB 3.84Å; L662-R694 HydrophobicContact CG-CG 4.32Å; K690-R694 VanDerWaalsContact CB-NH2 3.35Å; S691-R694 PolarHBondContact O-NH1 2.75Å; S691-R694 PolarHBondContact O-NH2 3.47Å; G692-R694 PolarHBondContact O-N 3.27Å; R694-N713 WeakPolarHBondContact O-CA 3.49Å; R694-V714 PolarHBondContact N-O 3.41Å; R694-V714 PolarHBondContact O-N 3.02Å; R694-V714 VanDerWaalsContact O-O 3.1Å; R694-V716 HydrophobicContact CB-CG2 4.4Å; R694-V716 HydrophobicContact CG-CG2 3.95Å
695Q97.4Very high94.4Very high3 Ų332.4 Ų32.41%0.01416%0.16CC..EExtended strand (participates in β ladder)trans-133.1126.1178.2-169.7176.788.800111.1Y165 G659 Q697 Y711 N713Y165-Q695 HydrophobicContact CD1-CB 3.95Å; Y165-Q695 HydrophobicContact CD2-CB 3.61Å; Y165-Q695 VanDerWaalsContact CD2-CD 3.45Å; Y165-Q695 HydrophobicContact CD2-CG 4.15Å; Y165-Q695 HydrophobicContact CE1-CB 4.23Å; Y165-Q695 HydrophobicContact CE2-CB 3.93Å; Y165-Q695 HydrophobicContact CE2-CG 4.46Å; Y165-Q695 HydrophobicContact CG-CB 3.63Å; G659-Q695 VanDerWaalsContact CA-O 3.3Å; G659-Q695 WeakPolarHBondContact CA-O 3.19Å; Q695-Q697 HydrophobicContact CG-CG 4.13Å; Q695-Y711 HydrophobicContact CG-CD2 4.13Å; Q695-N713 WeakPolarHBondContact CG-OD1 3.47Å; Q695-N713 PolarHBondContact NE2-OD1 2.74Å
696I97.8Very high93.8Very high0 Ų029.2 Ų29.20%014%0.144CC..EExtended strand (participates in β ladder)trans-83.7133.6166.5-56.1164.2000107.3I624 V626 I638 V657 L662 F663 Y711 R712 V714I624-I696 HydrophobicContact CD1-CG2 4.04Å; I624-I696 HydrophobicContact CG2-CB 4.43Å; I624-I696 HydrophobicContact CG2-CD1 4.2Å; I624-I696 HydrophobicContact CG2-CG2 4.11Å; V626-I696 HydrophobicContact CG2-CD1 3.92Å; I638-I696 HydrophobicContact CD1-CD1 3.57Å; I638-I696 HydrophobicContact CD1-CG1 4.27Å; I638-I696 HydrophobicContact CG1-CD1 3.89Å; I638-I696 HydrophobicContact CG2-CD1 4.07Å; V657-I696 HydrophobicContact CG1-CG2 3.75Å; L662-I696 HydrophobicContact CD1-CD1 4.49Å; L662-I696 HydrophobicContact CD1-CG1 3.48Å; L662-I696 VanDerWaalsContact CD1-CG1 3.48Å; F663-I696 HydrophobicContact CE2-CG2 4.25Å; I696-Y711 CarbonylContact O-C 3.5Å; I696-Y711 WeakPolarHBondContact O-CA 3.32Å; I696-Y711 WeakPolarHBondContact O-CB 3.31Å; I696-R712 PolarHBondContact N-O 2.87Å; I696-R712 PolarHBondContact O-N 2.79Å; I696-V714 HydrophobicContact CD1-CG2 3.56Å; I696-V714 HydrophobicContact CG1-CG2 3.94Å
697Q97.1Very high93.4Very high2 Ų228.4 Ų28.41%0.00914%0.139CC..EExtended strand (participates in β ladder)trans-126142.4177.9-59.4178.7-4.800109.7P180 W181 T256 V657 E658 Q695P180-Q697 HydrophobicContact CB-CG 3.99Å; W181-Q697 VanDerWaalsContact C-OE1 3.27Å; W181-Q697 PolarHBondContact O-NE2 2.93Å; T256-Q697 PolarHBondContact O-OE1 3.07Å; V657-Q697 VanDerWaalsContact CA-O 3.31Å; V657-Q697 WeakPolarHBondContact CA-O 3.36Å; E658-Q697 PolarHBondContact N-O 3Å; E658-Q697 PolarHBondContact O-N 3.04Å; Q695-Q697 HydrophobicContact CG-CG 4.13Å
698A96.3Very high93.1Very high0 Ų025.3 Ų25.30%012%0.12CC..EExtended strand (participates in β ladder)trans-132.9144.8-179.800000111.2I622 I624 L655 T656 V657 K709 G710I622-A698 HydrophobicContact CD1-CB 4.05Å; I622-A698 HydrophobicContact CG2-CB 3.99Å; I624-A698 HydrophobicContact CD1-CB 3.78Å; I624-A698 HydrophobicContact CG1-CB 4.49Å; L655-A698 HydrophobicContact CD1-CB 4.19Å; T656-A698 CarbonylContact O-C 3.49Å; T656-A698 VanDerWaalsContact O-CA 3.25Å; T656-A698 WeakPolarHBondContact O-CA 3.2Å; V657-A698 HydrophobicContact CG2-CB 4.28Å; A698-K709 CarbonylContact O-C 3.58Å; A698-K709 WeakPolarHBondContact O-CA 3.29Å; A698-G710 PolarHBondContact N-O 2.8Å; A698-G710 PolarHBondContact O-N 2.92Å
699N95.4Very high92.9Very high0 Ų027 Ų270%013%0.127CC..EExtended strand (participates in β ladder)trans-130.2131.7169-179.966.3000110.5T256 L655 T656 I708 K709T256-N699 HydrophobicContact CG2-CB 3.43Å; T256-N699 VanDerWaalsContact CG2-CB 3.43Å; L655-N699 CarbonylContact C-O 3.47Å; L655-N699 WeakPolarHBondContact CA-O 3.45Å; T656-N699 PolarHBondContact N-O 2.72Å; T656-N699 PolarHBondContact O-N 2.93Å; N699-I708 CarbonylContact C-O 3.52Å; N699-I708 VanDerWaalsContact CA-O 3.3Å; N699-I708 WeakPolarHBondContact CA-O 3.16Å; N699-I708 PolarHBondContact OD1-O 2.67Å; N699-K709 HydrophobicContact CB-CD 3.9Å; N699-K709 VanDerWaalsContact OD1-CD 3.31Å; N699-K709 WeakPolarHBondContact OD1-CD 3.45Å; N699-K709 WeakPolarHBondContact OD1-CE 3.44Å; N699-K709 PolarHBondContact OD1-NZ 3.13Å; N699-K709 VanDerWaalsContact OD1-NZ 3.17Å
700M94.1Very high92.9Very high0 Ų025.3 Ų25.30%012%0.122CC..EExtended strand (participates in β ladder)trans-106.3126.2168.8-173.769.872.200109.5I622 F642 C653 L655 L671 F705 D707 I708I622-M700 HydrophobicContact CD1-CB 3.88Å; F642-M700 HydrophobicContact CB-CE 3.8Å; F642-M700 HydrophobicContact CD1-CE 3.82Å; F642-M700 HydrophobicContact CD1-CG 4.2Å; F642-M700 HydrophobicContact CE1-CG 4.25Å; F642-M700 HydrophobicContact CG-CE 3.88Å; F642-M700 HydrophobicContact CG-CG 4.45Å; C653-M700 HydrophobicContact CB-SD 4.4Å; L655-M700 HydrophobicContact CB-CE 4.07Å; L655-M700 HydrophobicContact CB-SD 4.25Å; L655-M700 HydrophobicContact CD1-CE 4.05Å; L671-M700 HydrophobicContact CD1-CE 3.45Å; L671-M700 VanDerWaalsContact CD1-CE 3.45Å; L671-M700 HydrophobicContact CD1-SD 3.9Å; M700-F705 HydrophobicContact CG-CE2 3.78Å; M700-D707 CarbonylContact O-C 3.6Å; M700-I708 HydrophobicContact CB-CB 4.25Å; M700-I708 PolarHBondContact N-O 3.03Å; M700-I708 PolarHBondContact O-N 2.9Å
701R93Very high93Very high89 Ų8928.1 Ų28.134%0.33613%0.132SC..EExtended strand (participates in β ladder)trans-116.1153.5168.171.8175-163.6111.98.4110.4E254 C653 V654 K706E254-R701 HydrophobicContact CG-CB 4.33Å; E254-R701 WeakPolarHBondContact OE1-CD 3.41Å; E254-R701 IonicContact OE1-NH1 3.76Å; E254-R701 WeakPolarHBondContact OE2-CD 3.48Å; E254-R701 IonicContact OE2-NE 3.23Å; C653-R701 WeakPolarHBondContact CA-O 3.13Å; V654-R701 HydrophobicContact CB-CG 3.86Å; V654-R701 PolarHBondContact N-O 3.08Å; V654-R701 PolarHBondContact O-N 3.18Å; R701-K706 WeakPolarHBondContact CB-O 3.13Å
702S92.4Very high93.1Very high8 Ų833.3 Ų33.36%0.05615%0.148CC..  trans-153.7-179.1174.270.20000111.6V650 E651 K704 F705V650-S702 WeakPolarHBondContact CG1-OG 3.41Å; E651-S702 WeakPolarHBondContact O-CB 3.43Å; S702-K704 VanDerWaalsContact C-N 3.27Å; S702-K704 PolarHBondContact O-N 3.26Å; S702-K704 PolarHBondContact OG-N 3.42Å; S702-F705 PolarHBondContact N-O 3.16Å; S702-F705 WeakPolarHBondContact OG-CD1 3.36Å; S702-F705 WeakPolarHBondContact OG-CD2 3.16Å; S702-F705 WeakPolarHBondContact OG-CE2 3.34Å; S702-F705 VanDerWaalsContact OG-CG 3.27Å; S702-F705 WeakPolarHBondContact OG-CG 3.28Å; S702-F705 WeakPolarHBondContact OG-CZ 3.2Å; S702-F705 PolarHBondContact OG-N 2.86Å; S702-F705 PolarHBondContact OG-O 3.28Å
703N89.8Confident93.2Very high54 Ų5434.8 Ų34.829%0.28915%0.152SC..SBendtrans-62-33.417068.1-23.8000112.9E651 K706E651-N703 PolarHBondContact N-OD1 3.48Å; E651-N703 PolarHBondContact O-N 2.59Å; E651-N703 PolarHBondContact O-OD1 2.88Å; N703-K706 PolarHBondContact O-NZ 2.94Å
704K87.8Confident93.3Very high73 Ų7331.5 Ų31.532%0.31714%0.138SC..SBendtrans-95.2-23.7-174.9-65.8-70-178.4154.30115.1L646 E648 V650 S702L646-K704 HydrophobicContact CD1-CB 3.87Å; L646-K704 HydrophobicContact CD1-CG 4.02Å; E648-K704 IonicContact OE1-NZ 2.81Å; E648-K704 PolarHBondContact OE1-NZ 3.45Å; E648-K704 WeakPolarHBondContact OE2-CE 3.31Å; E648-K704 IonicContact OE2-NZ 3.16Å; E648-K704 PolarHBondContact OE2-NZ 2.67Å; V650-K704 HydrophobicContact CG1-CB 4.37Å; V650-K704 HydrophobicContact CG2-CB 4.36Å; V650-K704 HydrophobicContact CG2-CG 4.28Å; S702-K704 VanDerWaalsContact C-N 3.27Å; S702-K704 PolarHBondContact O-N 3.26Å; S702-K704 PolarHBondContact OG-N 3.42Å
705F83.8Confident93.3Very high3 Ų337.3 Ų37.31%0.01316%0.161CC..  trans-140.2128.717641.1-98.8000110.5Y619 F642 V650 M700 S702 I708Y619-F705 HydrophobicContact CE1-CB 3.78Å; Y619-F705 HydrophobicContact CE1-CG 4.39Å; F642-F705 HydrophobicContact CE1-CE2 4.1Å; F642-F705 AromaticContact CE1-CZ 3.63Å; F642-F705 HydrophobicContact CE1-CZ 3.63Å; F642-F705 HydrophobicContact CZ-CE1 4.23Å; F642-F705 AromaticContact CZ-CE2 3.87Å; F642-F705 HydrophobicContact CZ-CE2 3.87Å; F642-F705 AromaticContact CZ-CZ 3.53Å; F642-F705 HydrophobicContact CZ-CZ 3.53Å; V650-F705 HydrophobicContact CB-CE1 4.37Å; V650-F705 HydrophobicContact CG1-CE1 3.72Å; V650-F705 HydrophobicContact CG1-CZ 3.69Å; V650-F705 HydrophobicContact CG2-CE1 3.89Å; V650-F705 HydrophobicContact CG2-CZ 4.46Å; M700-F705 HydrophobicContact CG-CE2 3.78Å; S702-F705 PolarHBondContact N-O 3.16Å; S702-F705 WeakPolarHBondContact OG-CD1 3.36Å; S702-F705 WeakPolarHBondContact OG-CD2 3.16Å; S702-F705 WeakPolarHBondContact OG-CE2 3.34Å; S702-F705 VanDerWaalsContact OG-CG 3.27Å; S702-F705 WeakPolarHBondContact OG-CG 3.28Å; S702-F705 WeakPolarHBondContact OG-CZ 3.2Å; S702-F705 PolarHBondContact OG-N 2.86Å; S702-F705 PolarHBondContact OG-O 3.28Å; F705-I708 HydrophobicContact CB-CD1 4.37Å; F705-I708 HydrophobicContact CB-CG1 4.42Å; F705-I708 HydrophobicContact CD1-CD1 4.19Å; F705-I708 HydrophobicContact CD2-CD1 3.43Å; F705-I708 VanDerWaalsContact CD2-CD1 3.43Å; F705-I708 HydrophobicContact CD2-CG1 3.81Å; F705-I708 HydrophobicContact CE1-CD1 4.36Å; F705-I708 HydrophobicContact CE2-CD1 3.66Å; F705-I708 HydrophobicContact CE2-CG1 4.38Å; F705-I708 HydrophobicContact CG-CD1 3.74Å; F705-I708 HydrophobicContact CG-CG1 4.21Å; F705-I708 HydrophobicContact CZ-CD1 4.12Å
706K82.6Confident93.3Very high86 Ų8637.2 Ų37.237%0.37416%0.16SC..SBendtrans-80.5-33.1-172.8-54.2-52-177.9-1680112.7T590 R701 N703T590-K706 HydrophobicContact CG2-CB 4.11Å; R701-K706 WeakPolarHBondContact CB-O 3.13Å; N703-K706 PolarHBondContact O-NZ 2.94Å
707D88.4Confident93.2Very high2 Ų241.1 Ų41.11%0.01118%0.181CC..  trans-142.4136.5176.271.7-62000111.5R177 A253 K592 M700R177-D707 IonicContact CZ-OD2 3.38Å; R177-D707 IonicContact NH1-OD2 2.71Å; R177-D707 PolarHBondContact NH1-OD2 2.7Å; R177-D707 IonicContact NH2-OD2 3.8Å; R177-D707 PolarHBondContact NH2-OD2 2.67Å; A253-D707 HydrophobicContact CB-CB 3.9Å; A253-D707 WeakPolarHBondContact O-CB 3.35Å; K592-D707 PolarHBondContact NZ-O 3.4Å; K592-D707 IonicContact NZ-OD1 2.88Å; K592-D707 PolarHBondContact NZ-OD1 3.17Å; K592-D707 IonicContact NZ-OD2 3.83Å; K592-D707 PolarHBondContact NZ-OD2 3.48Å; M700-D707 CarbonylContact O-C 3.6Å
708I91.2Very high92.9Very high6 Ų648.2 Ų48.23%0.03121%0.212CC..EExtended strand (participates in β ladder)trans-138.6119.3159-58.4178.7000105.7Y619 P620 I622 F642 N699 M700 F705Y619-I708 HydrophobicContact CD1-CD1 3.71Å; Y619-I708 HydrophobicContact CD1-CG1 3.94Å; Y619-I708 HydrophobicContact CE1-CD1 4.41Å; P620-I708 WeakPolarHBondContact O-CG2 3.43Å; I622-I708 HydrophobicContact CD1-CG2 4.47Å; I622-I708 WeakPolarHBondContact CD1-O 3.25Å; I622-I708 HydrophobicContact CG1-CG2 4.09Å; F642-I708 HydrophobicContact CE2-CB 4.45Å; F642-I708 HydrophobicContact CE2-CD1 3.35Å; F642-I708 HydrophobicContact CE2-CG1 4.47Å; F642-I708 HydrophobicContact CE2-CG2 4.08Å; F642-I708 HydrophobicContact CZ-CD1 3.45Å; F642-I708 VanDerWaalsContact CZ-CD1 3.45Å; N699-I708 CarbonylContact C-O 3.52Å; N699-I708 VanDerWaalsContact CA-O 3.3Å; N699-I708 WeakPolarHBondContact CA-O 3.16Å; N699-I708 PolarHBondContact OD1-O 2.67Å; M700-I708 HydrophobicContact CB-CB 4.25Å; M700-I708 PolarHBondContact N-O 3.03Å; M700-I708 PolarHBondContact O-N 2.9Å; F705-I708 HydrophobicContact CB-CD1 4.37Å; F705-I708 HydrophobicContact CB-CG1 4.42Å; F705-I708 HydrophobicContact CD1-CD1 4.19Å; F705-I708 HydrophobicContact CD2-CD1 3.43Å; F705-I708 VanDerWaalsContact CD2-CD1 3.43Å; F705-I708 HydrophobicContact CD2-CG1 3.81Å; F705-I708 HydrophobicContact CE1-CD1 4.36Å; F705-I708 HydrophobicContact CE2-CD1 3.66Å; F705-I708 HydrophobicContact CE2-CG1 4.38Å; F705-I708 HydrophobicContact CG-CD1 3.74Å; F705-I708 HydrophobicContact CG-CG1 4.21Å; F705-I708 HydrophobicContact CZ-CD1 4.12Å
709K92Very high92.1Very high34 Ų3450.9 Ų50.915%0.14823%0.234CC..EExtended strand (participates in β ladder)trans-101.8151.1-174.8-55.5-71.8177.1177.10110.8P180 A253 E254 W255 T256 A698 N699P180-K709 HydrophobicContact CG-CB 4.25Å; A253-K709 WeakPolarHBondContact O-CE 3.3Å; A253-K709 PolarHBondContact O-NZ 2.9Å; E254-K709 PolarHBondContact O-NZ 3.01Å; E254-K709 VanDerWaalsContact O-NZ 3.11Å; W255-K709 PolarHBondContact O-NZ 3.14Å; T256-K709 HydrophobicContact CG2-CD 4.19Å; A698-K709 CarbonylContact O-C 3.58Å; A698-K709 WeakPolarHBondContact O-CA 3.29Å; N699-K709 HydrophobicContact CB-CD 3.9Å; N699-K709 VanDerWaalsContact OD1-CD 3.31Å; N699-K709 WeakPolarHBondContact OD1-CD 3.45Å; N699-K709 WeakPolarHBondContact OD1-CE 3.44Å; N699-K709 PolarHBondContact OD1-NZ 3.13Å; N699-K709 VanDerWaalsContact OD1-NZ 3.17Å
710G94.8Very high90.3Very high7 Ų762.6 Ų62.67%0.07230%0.295CS..EExtended strand (participates in β ladder)trans-151.8162.7165.800000110.8A698A698-G710 PolarHBondContact N-O 2.8Å; A698-G710 PolarHBondContact O-N 2.92Å
711Y96.8Very high90.1Very high85 Ų8565.7 Ų65.733%0.33331%0.31SS..EExtended strand (participates in β ladder)trans-147.1163178.572.1-82.6000111.8F167 P180 Q695 I696F167-Y711 AromaticContact CE1-CD1 3.73Å; F167-Y711 HydrophobicContact CE1-CD1 3.73Å; F167-Y711 HydrophobicContact CE1-CD2 4.23Å; F167-Y711 AromaticContact CE1-CE1 3.51Å; F167-Y711 HydrophobicContact CE1-CE1 3.51Å; F167-Y711 HydrophobicContact CE1-CE2 4.04Å; F167-Y711 HydrophobicContact CE1-CG 4.09Å; F167-Y711 AromaticContact CE1-CZ 3.68Å; F167-Y711 HydrophobicContact CZ-CD1 4.27Å; F167-Y711 AromaticContact CZ-CD2 3.99Å; F167-Y711 HydrophobicContact CZ-CD2 3.99Å; F167-Y711 AromaticContact CZ-CE1 3.85Å; F167-Y711 HydrophobicContact CZ-CE1 3.85Å; F167-Y711 AromaticContact CZ-CE2 3.56Å; F167-Y711 HydrophobicContact CZ-CE2 3.56Å; F167-Y711 HydrophobicContact CZ-CG 4.33Å; F167-Y711 AromaticContact CZ-CZ 3.48Å; F167-Y711 VanDerWaalsContact CZ-CZ 3.48Å; P180-Y711 HydrophobicContact CB-CD1 4.22Å; P180-Y711 HydrophobicContact CB-CG 4.2Å; P180-Y711 HydrophobicContact CG-CD1 4.2Å; P180-Y711 HydrophobicContact CG-CG 4.46Å; Q695-Y711 HydrophobicContact CG-CD2 4.13Å; I696-Y711 CarbonylContact O-C 3.5Å; I696-Y711 WeakPolarHBondContact O-CA 3.32Å; I696-Y711 WeakPolarHBondContact O-CB 3.31Å
712R97.3Very high89.9Confident134 Ų13464.5 Ų64.551%0.50631%0.309SS..EExtended strand (participates in β ladder)trans-148.3126169.9-177.568177.6-170.7-1.9110.1I624 V626 I696 V714I624-R712 HydrophobicContact CB-CB 3.8Å; I624-R712 HydrophobicContact CG2-CB 3.9Å; V626-R712 HydrophobicContact CG2-CG 4.28Å; I696-R712 PolarHBondContact N-O 2.87Å; I696-R712 PolarHBondContact O-N 2.79Å; R712-V714 HydrophobicContact CG-CG2 4.48Å
713N97.1Very high89.8Confident46 Ų4667.6 Ų67.625%0.24632%0.323CS..EExtended strand (participates in β ladder)trans-73.6140.8170.4-72.1-12000110.9D435 R694 Q695D435-N713 PolarHBondContact OD2-ND2 2.8Å; R694-N713 WeakPolarHBondContact O-CA 3.49Å; Q695-N713 WeakPolarHBondContact CG-OD1 3.47Å; Q695-N713 PolarHBondContact NE2-OD1 2.74Å
714V96.9Very high89.8Confident11 Ų1168.4 Ų68.47%0.06733%0.325CS..EExtended strand (participates in β ladder)trans-139.9130.9-178.7-174.10000108.4V626 A630 R694 I696 R712 V716V626-V714 HydrophobicContact CG2-CG2 3.59Å; A630-V714 HydrophobicContact CB-CG1 3.53Å; R694-V714 PolarHBondContact N-O 3.41Å; R694-V714 PolarHBondContact O-N 3.02Å; R694-V714 VanDerWaalsContact O-O 3.1Å; I696-V714 HydrophobicContact CD1-CG2 3.56Å; I696-V714 HydrophobicContact CG1-CG2 3.94Å; R712-V714 HydrophobicContact CG-CG2 4.48Å; V714-V716 HydrophobicContact CG1-CG2 4.46Å
715Y97.2Very high89.9Confident140 Ų14068.1 Ų68.155%0.54933%0.325SS..EExtended strand (participates in β ladder)trans-94.7127.1169.2-165.5-90.3000108.7Q693 D717Q693-Y715 HydrophobicContact CB-CD2 4.43Å; Y715-D717 WeakPolarHBondContact CE1-OD1 3.35Å
716V97.9Very high90.3Very high1 Ų172.5 Ų72.51%0.00635%0.346CS..EExtended strand (participates in β ladder)trans-106.1118.2-178.5-172.50000109.8A630 V632 L662 P688 K690 S691 G692 R694 V714A630-V716 HydrophobicContact CB-CB 4.45Å; A630-V716 HydrophobicContact CB-CG1 4.46Å; A630-V716 HydrophobicContact CB-CG2 4.09Å; A630-V716 CarbonylContact O-C 3.57Å; A630-V716 WeakPolarHBondContact O-CA 3.24Å; V632-V716 HydrophobicContact CG2-CG1 3.79Å; L662-V716 HydrophobicContact CD2-CG2 3.63Å; P688-V716 HydrophobicContact CB-CG1 3.65Å; P688-V716 HydrophobicContact CB-CG2 4.25Å; P688-V716 HydrophobicContact CG-CG1 4.4Å; K690-V716 WeakPolarHBondContact O-CG1 3.22Å; S691-V716 CarbonylContact C-O 3.48Å; S691-V716 WeakPolarHBondContact CA-O 3.36Å; G692-V716 PolarHBondContact N-O 3.41Å; G692-V716 PolarHBondContact O-N 3.06Å; R694-V716 HydrophobicContact CB-CG2 4.4Å; R694-V716 HydrophobicContact CG-CG2 3.95Å; V714-V716 HydrophobicContact CG1-CG2 4.46Å
717D96.3Very high90.9Very high83 Ų8371.5 Ų71.544%0.44434%0.344SS..BIsolated β-bridgetrans-82.9156.1179.4-68.3-53.3000112.4A630 I631 V632 Y715A630-D717 PolarHBondContact O-N 3.39Å; I631-D717 WeakPolarHBondContact CA-O 3.45Å; V632-D717 WeakPolarHBondContact CG2-O 3.38Å; V632-D717 PolarHBondContact N-O 3.02Å; Y715-D717 WeakPolarHBondContact CE1-OD1 3.35Å
718F90.9Very high91.1Very high151 Ų15176.8 Ų76.866%0.66237%0.37SS*.PPolyproline II helixtrans-69.8143164.9-73.5-79000110S691 L720S691-F718 WeakPolarHBondContact OG-CE2 3.46Å; S691-F718 WeakPolarHBondContact OG-CZ 3.43Å; F718-L720 PolarHBondContact O-N 3.34Å
719A77.6Confident91.1Very high56 Ų5682.8 Ų82.846%0.46340%0.398SS..PPolyproline II helixtrans-64.9121.9165.200000108.3I631I631-A719 HydrophobicContact CG2-CB 3.87Å
720L58.1Low91Very high245 Ų24587.2 Ų87.2100%1.28342%0.421SS*.  trans-68.70172.8-75.3168.8000111.9F718F718-L720 PolarHBondContact O-N 3.34Å

Retrieved 720 of 720 residues in 139.7 ms (Link to these results)