A0A096NC17_PAPAN Loading...

Equilibrative nucleoside transporter 2

Bidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent, passive transporter. Involved in the transport of nucleosides such as inosine, adenosine, uridine, thymidine, cytidine and guanosine. Also able to transport purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Involved in nucleoside transport at basolateral membrane of kidney cells, allowing liver absorption of nucleoside metabolites. Mediates apical nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis-barrier. Mediates both the influx and efflux of hypoxanthine in skeletal muscle microvascular endothelial cells to control the amount of intracellular hypoxanthine available for xanthine oxidase-mediated ROS production.

AlphaFold DB , UniProt , Accession A0A096NC17, Species PAPAN (Papio anubis, Olive baboon), Gene SLC29A2, Length 456 aa.

Structure Viewer

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37	Very low	59.4	Low	249 Å²	249	128.5 Å²	128.5	100%	1.227	67%	0.669	S	S	*	*				0	129.1	0	-81.8	174.3	176	0	0	107.6
2	A	34.1	Very low	61.6	Low	98 Å²	98	129.3 Å²	129.3	81%	0.81	67%	0.666	S	S	*	*			trans	-54.2	142.5	-174.6	0	0	0	0	0	112.1	G4	A2-G4 VanDerWaalsContact C-N 3.34Å; A2-G4 PolarHBondContact O-N 3.47Å
3	R	40.1	Very low	63.7	Low	227 Å²	227	125.3 Å²	125.3	86%	0.857	65%	0.646	S	S	*	*			trans	-51.7	98.3	165.1	-82.4	175.1	167.6	172.3	-7.1	107.9	D5	R3-D5 PolarHBondContact O-N 3.47Å
4	G	45.3	Very low	65.5	Low	63 Å²	63	116.4 Å²	116.4	65%	0.649	60%	0.6	S	S	*	*	P	Polyproline II helix	trans	-70.8	121.3	169.3	0	0	0	0	0	107.6	A2 A6	A2-G4 VanDerWaalsContact C-N 3.34Å; A2-G4 PolarHBondContact O-N 3.47Å; G4-A6 PolarHBondContact O-N 3.15Å
5	D	58.3	Low	67.1	Low	157 Å²	157	108.7 Å²	108.7	84%	0.84	56%	0.562	S	S	*	*	P	Polyproline II helix	trans	-47.2	139.6	170.9	-70.9	-39.7	0	0	0	110.1	R3	R3-D5 PolarHBondContact O-N 3.47Å
6	A	65	Low	68.7	Low	44 Å²	44	107.2 Å²	107.2	36%	0.364	55%	0.553	S	S	.	*	P	Polyproline II helix	trans	-51	130.8	175.8	0	0	0	0	0	109	G4 R8 Y221	G4-A6 PolarHBondContact O-N 3.15Å; A6-R8 PolarHBondContact O-N 3.13Å; A6-Y221 HydrophobicContact CB-CE1 4.12Å
7	P	73.6	Confident	70.2	Confident	41 Å²	41	101.4 Å²	101.4	27%	0.266	53%	0.525	S	S	.	.	P	Polyproline II helix	trans	-56.4	142.1	-177.9	22.5	-32.1	0	0	0	109.3	F218 Y221	P7-F218 HydrophobicContact CG-CD2 4.48Å; P7-F218 WeakPolarHBondContact O-CD2 3.44Å; P7-F218 WeakPolarHBondContact O-CE2 3.44Å; P7-Y221 HydrophobicContact CG-CD1 4.27Å; P7-Y221 HydrophobicContact CG-CD2 4.28Å; P7-Y221 HydrophobicContact CG-CG 3.81Å
8	R	76	Confident	71.5	Confident	226 Å²	226	95.8 Å²	95.8	85%	0.853	50%	0.495	S	S	*	.	P	Polyproline II helix	trans	-81	139.6	172.5	-69.1	-176.2	177.7	-179.6	-0.3	109.8	A6 S10	A6-R8 PolarHBondContact O-N 3.13Å; R8-S10 PolarHBondContact O-N 2.93Å; R8-S10 PolarHBondContact O-OG 3.17Å
9	D	78.8	Confident	72.8	Confident	24 Å²	24	93.3 Å²	93.3	13%	0.128	48%	0.481	C	S	.	.			trans	-67.7	94.4	172.7	-174.4	10	0	0	0	109.7	Y11 H12 L13 V14 G15 Y159 F218	D9-Y11 PolarHBondContact O-N 3.46Å; D9-H12 PolarHBondContact O-N 3.4Å; D9-H12 WeakPolarHBondContact OD2-CA 3.3Å; D9-L13 PolarHBondContact OD1-N 3.2Å; D9-V14 PolarHBondContact OD1-N 2.87Å; D9-G15 PolarHBondContact OD2-N 3.18Å; D9-Y159 WeakPolarHBondContact CB-OH 3.29Å; D9-Y159 PolarHBondContact OD2-OH 3.41Å; D9-F218 HydrophobicContact CB-CD2 3.91Å; D9-F218 HydrophobicContact CB-CE2 4.22Å; D9-F218 HydrophobicContact CB-CG 4.09Å
10	S	69.1	Low	74	Confident	81 Å²	81	90.7 Å²	90.7	57%	0.566	47%	0.467	S	S	*	.	G	3₁₀ helix	trans	-68.3	124.7	-176.3	-59.3	0	0	0	0	109.5	R8 H12	R8-S10 PolarHBondContact O-N 2.93Å; R8-S10 PolarHBondContact O-OG 3.17Å; S10-H12 PolarHBondContact O-N 2.85Å
11	Y	76.6	Confident	75	Confident	203 Å²	203	86.4 Å²	86.4	80%	0.796	45%	0.445	S	S	*	.	G	3₁₀ helix	trans	61.5	17.6	-176.8	-47.9	-78.4	0	0	0	115.4	D9 L13	D9-Y11 PolarHBondContact O-N 3.46Å; Y11-L13 PolarHBondContact O-N 2.68Å; Y11-L13 VanDerWaalsContact O-N 3.13Å
12	H	85.8	Confident	77.8	Confident	138 Å²	138	74.5 Å²	74.5	64%	0.639	39%	0.386	S	S	*	.	G	3₁₀ helix	trans	55.5	26.7	-178.6	-56.2	-67.6	0	0	0	114.3	D9 S10 V14 G15 I16	D9-H12 PolarHBondContact O-N 3.4Å; D9-H12 WeakPolarHBondContact OD2-CA 3.3Å; S10-H12 PolarHBondContact O-N 2.85Å; H12-V14 VanDerWaalsContact C-N 3.33Å; H12-V14 PolarHBondContact O-N 3.38Å; H12-G15 PolarHBondContact O-N 2.94Å; H12-G15 VanDerWaalsContact O-N 3.17Å; H12-I16 WeakPolarHBondContact O-CG1 3.37Å; H12-I16 PolarHBondContact O-N 3.11Å
13	L	88.1	Confident	80.8	Confident	78 Å²	78	70.6 Å²	70.6	41%	0.408	35%	0.352	S	S	.	.	H	α-helix	trans	-62.5	-40.1	-175.2	-72.8	175.8	0	0	0	111.9	D9 Y11 G15 I16 S17 L216	D9-L13 PolarHBondContact OD1-N 3.2Å; Y11-L13 PolarHBondContact O-N 2.68Å; Y11-L13 VanDerWaalsContact O-N 3.13Å; L13-G15 VanDerWaalsContact C-N 3.33Å; L13-I16 PolarHBondContact O-N 3.01Å; L13-S17 PolarHBondContact O-N 3.44Å; L13-S17 PolarHBondContact O-OG 2.89Å; L13-L216 HydrophobicContact CB-CD1 4.03Å; L13-L216 HydrophobicContact CB-CD2 4.36Å; L13-L216 HydrophobicContact CD1-CD2 4.06Å
14	V	88.8	Confident	83.4	Confident	0 Å²	0	59.9 Å²	59.9	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-65.3	-41.5	177.1	179.6	0	0	0	0	110.2	D9 H12 I16 S17 F18 Y159 L213 L216 F218 A219	D9-V14 PolarHBondContact OD1-N 2.87Å; H12-V14 VanDerWaalsContact C-N 3.33Å; H12-V14 PolarHBondContact O-N 3.38Å; V14-I16 PolarHBondContact O-N 2.9Å; V14-S17 PolarHBondContact O-N 3.23Å; V14-F18 HydrophobicContact CG1-CD2 3.74Å; V14-F18 HydrophobicContact CG1-CE2 3.66Å; V14-F18 VanDerWaalsContact O-CD2 3.32Å; V14-F18 WeakPolarHBondContact O-CD2 3.21Å; V14-F18 PolarHBondContact O-N 3.43Å; V14-Y159 HydrophobicContact CB-CE1 3.91Å; V14-Y159 HydrophobicContact CG1-CD1 4.01Å; V14-Y159 HydrophobicContact CG1-CE1 3.68Å; V14-L213 HydrophobicContact CG1-CD2 4.23Å; V14-L216 HydrophobicContact CG2-CB 4.1Å; V14-L216 HydrophobicContact CG2-CD1 3.62Å; V14-L216 HydrophobicContact CG2-CG 4.5Å; V14-F218 HydrophobicContact CB-CD1 4.21Å; V14-F218 HydrophobicContact CG1-CD1 4.11Å; V14-F218 HydrophobicContact CG2-CB 4.05Å; V14-F218 HydrophobicContact CG2-CD1 3.95Å; V14-F218 HydrophobicContact CG2-CG 4.34Å; V14-A219 HydrophobicContact CG1-CB 4.47Å; V14-A219 HydrophobicContact CG2-CB 4.06Å
15	G	89.6	Confident	85.7	Confident	2 Å²	2	57.2 Å²	57.2	2%	0.021	28%	0.283	C	S	.	.	H	α-helix	trans	-59.5	-46.5	175.7	0	0	0	0	0	112.5	D9 H12 L13 F18 F19	D9-G15 PolarHBondContact OD2-N 3.18Å; H12-G15 PolarHBondContact O-N 2.94Å; H12-G15 VanDerWaalsContact O-N 3.17Å; L13-G15 VanDerWaalsContact C-N 3.33Å; G15-F18 PolarHBondContact O-N 3.47Å; G15-F19 WeakPolarHBondContact O-CB 3.29Å; G15-F19 PolarHBondContact O-N 3.5Å
16	I	93.2	Very high	87.4	Confident	84 Å²	84	51.3 Å²	51.3	43%	0.431	25%	0.252	S	S	.	.	H	α-helix	trans	-63	-42.1	176.8	-66.4	165.9	0	0	0	110.8	H12 L13 V14 F18 F19 I20	H12-I16 WeakPolarHBondContact O-CG1 3.37Å; H12-I16 PolarHBondContact O-N 3.11Å; L13-I16 PolarHBondContact O-N 3.01Å; V14-I16 PolarHBondContact O-N 2.9Å; I16-F18 PolarHBondContact O-N 3.27Å; I16-F19 WeakPolarHBondContact O-CB 3.43Å; I16-F19 PolarHBondContact O-N 3.04Å; I16-I20 HydrophobicContact CG2-CD1 3.82Å; I16-I20 HydrophobicContact CG2-CG1 4.43Å; I16-I20 WeakPolarHBondContact O-CG1 3.48Å; I16-I20 PolarHBondContact O-N 3.23Å
17	S	93.7	Very high	88.8	Confident	9 Å²	9	49.5 Å²	49.5	6%	0.063	24%	0.236	C	C	.	.	H	α-helix	trans	-60.2	-45.7	176.6	-63	0	0	0	0	112	L13 V14 I20 L21	L13-S17 PolarHBondContact O-N 3.44Å; L13-S17 PolarHBondContact O-OG 2.89Å; V14-S17 PolarHBondContact O-N 3.23Å; S17-I20 PolarHBondContact O-N 2.79Å; S17-L21 WeakPolarHBondContact O-CB 3.4Å; S17-L21 VanDerWaalsContact O-CG 3.28Å; S17-L21 WeakPolarHBondContact O-CG 3.13Å; S17-L21 PolarHBondContact O-N 2.88Å
18	F	94.1	Very high	89.9	Confident	0 Å²	0	47.8 Å²	47.8	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-68.8	-34.2	176.8	-81.4	-68.9	0	0	0	113	V14 G15 I16 L21 G22 L152 M155 Y159 F163 L213	V14-F18 HydrophobicContact CG1-CD2 3.74Å; V14-F18 HydrophobicContact CG1-CE2 3.66Å; V14-F18 VanDerWaalsContact O-CD2 3.32Å; V14-F18 WeakPolarHBondContact O-CD2 3.21Å; V14-F18 PolarHBondContact O-N 3.43Å; G15-F18 PolarHBondContact O-N 3.47Å; I16-F18 PolarHBondContact O-N 3.27Å; F18-L21 HydrophobicContact CD1-CD1 4.08Å; F18-L21 HydrophobicContact CE1-CD1 4.33Å; F18-L21 PolarHBondContact O-N 3.35Å; F18-G22 PolarHBondContact O-N 3.26Å; F18-L152 HydrophobicContact CD1-CD1 4.38Å; F18-L152 HydrophobicContact CD1-CD2 3.51Å; F18-L152 HydrophobicContact CD1-CG 4.05Å; F18-L152 HydrophobicContact CD2-CD2 4.3Å; F18-L152 HydrophobicContact CE1-CD2 3.66Å; F18-L152 HydrophobicContact CE1-CG 3.97Å; F18-L152 HydrophobicContact CE2-CD2 4.44Å; F18-L152 HydrophobicContact CG-CD2 3.86Å; F18-L152 HydrophobicContact CZ-CD2 4.13Å; F18-M155 HydrophobicContact CD2-SD 4.29Å; F18-M155 HydrophobicContact CE2-CE 3.69Å; F18-M155 HydrophobicContact CE2-SD 3.39Å; F18-M155 WeakPolarHBondContact CE2-SD 3.32Å; F18-M155 HydrophobicContact CZ-CE 3.77Å; F18-M155 HydrophobicContact CZ-SD 3.74Å; F18-Y159 HydrophobicContact CD2-CD1 4.09Å; F18-F163 HydrophobicContact CB-CB 4.42Å; F18-F163 HydrophobicContact CD1-CD2 4.44Å; F18-F163 WeakPolarHBondContact O-CA 3.44Å; F18-F163 VanDerWaalsContact O-CD2 3.3Å; F18-F163 WeakPolarHBondContact O-CD2 3.3Å; F18-L213 HydrophobicContact CE2-CD1 4.44Å; F18-L213 HydrophobicContact CE2-CD2 4.32Å; F18-L213 HydrophobicContact CZ-CD1 4.14Å
19	F	95.7	Very high	90.8	Very high	49 Å²	49	39.2 Å²	39.2	22%	0.215	19%	0.192	C	C	.	.	H	α-helix	trans	-60.3	-47.5	171.7	-178.1	-90.2	0	0	0	111.8	G15 I16 G22 L23 L162 G166 L169	G15-F19 WeakPolarHBondContact O-CB 3.29Å; G15-F19 PolarHBondContact O-N 3.5Å; I16-F19 WeakPolarHBondContact O-CB 3.43Å; I16-F19 PolarHBondContact O-N 3.04Å; F19-G22 PolarHBondContact O-N 2.96Å; F19-L23 PolarHBondContact O-N 3.19Å; F19-L162 HydrophobicContact CB-CD2 4.31Å; F19-L162 WeakPolarHBondContact CD2-O 3.28Å; F19-G166 WeakPolarHBondContact O-CA 3.13Å; F19-L169 HydrophobicContact CE1-CD2 3.72Å; F19-L169 HydrophobicContact CZ-CB 4.21Å; F19-L169 HydrophobicContact CZ-CD2 3.53Å; F19-L169 HydrophobicContact CZ-CG 4.48Å
20	I	96.5	Very high	91.5	Very high	40 Å²	40	39.6 Å²	39.6	21%	0.205	19%	0.194	C	C	.	.	H	α-helix	trans	-66.4	-39	177.2	-66	169	0	0	0	111	I16 S17 G22 L23 G24 M205 S206	I16-I20 HydrophobicContact CG2-CD1 3.82Å; I16-I20 HydrophobicContact CG2-CG1 4.43Å; I16-I20 WeakPolarHBondContact O-CG1 3.48Å; I16-I20 PolarHBondContact O-N 3.23Å; S17-I20 PolarHBondContact O-N 2.79Å; I20-G22 VanDerWaalsContact C-N 3.34Å; I20-G22 PolarHBondContact O-N 3.47Å; I20-L23 WeakPolarHBondContact O-CB 3.38Å; I20-L23 PolarHBondContact O-N 3.45Å; I20-G24 PolarHBondContact O-N 2.76Å; I20-M205 HydrophobicContact CG2-CB 4.25Å; I20-S206 PolarHBondContact O-OG 3.17Å
21	L	96.3	Very high	92.8	Very high	1 Å²	1	36 Å²	36	1%	0.005	17%	0.168	C	C	.	.	H	α-helix	trans	-60.4	-44.7	173.6	-77.5	163.5	0	0	0	111.3	S17 F18 L23 G24 T25 L103 L148 F163 Y210 L213	S17-L21 WeakPolarHBondContact O-CB 3.4Å; S17-L21 VanDerWaalsContact O-CG 3.28Å; S17-L21 WeakPolarHBondContact O-CG 3.13Å; S17-L21 PolarHBondContact O-N 2.88Å; F18-L21 HydrophobicContact CD1-CD1 4.08Å; F18-L21 HydrophobicContact CE1-CD1 4.33Å; F18-L21 PolarHBondContact O-N 3.35Å; L21-L23 VanDerWaalsContact C-N 3.34Å; L21-L23 PolarHBondContact O-N 3.32Å; L21-G24 PolarHBondContact O-N 3.16Å; L21-T25 VanDerWaalsContact O-CG2 3.29Å; L21-T25 WeakPolarHBondContact O-CG2 3.47Å; L21-T25 PolarHBondContact O-N 3.01Å; L21-T25 VanDerWaalsContact O-N 3.1Å; L21-L103 HydrophobicContact CD2-CD1 4.48Å; L21-L148 HydrophobicContact CD1-CD2 4.27Å; L21-L148 HydrophobicContact CD2-CD2 4.48Å; L21-F163 HydrophobicContact CB-CD2 4.3Å; L21-F163 HydrophobicContact CB-CE2 4.15Å; L21-Y210 HydrophobicContact CD1-CD2 4.29Å; L21-L213 HydrophobicContact CD1-CD1 4.09Å
22	G	96.1	Very high	93.7	Very high	0 Å²	0	26.3 Å²	26.3	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-56.4	-49	173.9	0	0	0	0	0	111.7	F18 F19 I20 G24 T25 F163 Q167	F18-G22 PolarHBondContact O-N 3.26Å; F19-G22 PolarHBondContact O-N 2.96Å; I20-G22 VanDerWaalsContact C-N 3.34Å; I20-G22 PolarHBondContact O-N 3.47Å; G22-G24 PolarHBondContact O-N 2.76Å; G22-T25 PolarHBondContact O-N 2.96Å; G22-T25 PolarHBondContact O-OG1 3.34Å; G22-F163 VanDerWaalsContact CA-CD2 3.46Å; G22-F163 WeakPolarHBondContact CA-O 3.43Å; G22-F163 VanDerWaalsContact N-CE2 3.34Å; G22-Q167 VanDerWaalsContact O-CG 3.26Å; G22-Q167 WeakPolarHBondContact O-CG 3.44Å
23	L	95.9	Very high	93.9	Very high	15 Å²	15	22.6 Å²	22.6	8%	0.079	12%	0.115	C	C	.	.	H	α-helix	trans	-53.8	-52.1	174.3	-173.7	79.3	0	0	0	111.4	F19 I20 L21 T25 L26 L27 G166 L169 A170 F173	F19-L23 PolarHBondContact O-N 3.19Å; I20-L23 WeakPolarHBondContact O-CB 3.38Å; I20-L23 PolarHBondContact O-N 3.45Å; L21-L23 VanDerWaalsContact C-N 3.34Å; L21-L23 PolarHBondContact O-N 3.32Å; L23-T25 PolarHBondContact O-N 3.42Å; L23-L26 PolarHBondContact O-N 3.17Å; L23-L27 WeakPolarHBondContact O-CB 3.36Å; L23-L27 PolarHBondContact O-N 3.14Å; L23-G166 WeakPolarHBondContact CA-O 3.3Å; L23-G166 WeakPolarHBondContact CD1-O 3.41Å; L23-L169 HydrophobicContact CD1-CB 3.99Å; L23-L169 HydrophobicContact CD1-CD2 4.19Å; L23-L169 HydrophobicContact CD1-CG 4.04Å; L23-A170 HydrophobicContact CD1-CB 3.86Å; L23-F173 HydrophobicContact CD1-CD2 3.85Å; L23-F173 HydrophobicContact CD1-CE2 3.89Å; L23-F173 HydrophobicContact CD2-CE2 4.11Å
24	G	94.9	Very high	94.1	Very high	3 Å²	3	20 Å²	20	3%	0.031	10%	0.102	C	C	.	.	H	α-helix	trans	-62.6	-22.8	-178.3	0	0	0	0	0	115.2	I20 L21 G22 P28 S206	I20-G24 PolarHBondContact O-N 2.76Å; L21-G24 PolarHBondContact O-N 3.16Å; G22-G24 PolarHBondContact O-N 2.76Å; G24-P28 WeakPolarHBondContact O-CD 2.95Å; G24-S206 WeakPolarHBondContact CA-OG 3.16Å
25	T	94.8	Very high	94.3	Very high	6 Å²	6	20 Å²	20	4%	0.037	10%	0.102	C	C	.	.	H	α-helix	trans	-75.5	-34.7	179.1	60.7	0	0	0	0	114.1	L21 G22 L23 L144 L148 F163 Q167	L21-T25 VanDerWaalsContact O-CG2 3.29Å; L21-T25 WeakPolarHBondContact O-CG2 3.47Å; L21-T25 PolarHBondContact O-N 3.01Å; L21-T25 VanDerWaalsContact O-N 3.1Å; G22-T25 PolarHBondContact O-N 2.96Å; G22-T25 PolarHBondContact O-OG1 3.34Å; L23-T25 PolarHBondContact O-N 3.42Å; T25-L144 HydrophobicContact CG2-CD2 3.81Å; T25-L144 HydrophobicContact CG2-CG 3.97Å; T25-L148 HydrophobicContact CG2-CD1 3.56Å; T25-F163 HydrophobicContact CG2-CE2 4.27Å; T25-F163 HydrophobicContact CG2-CZ 3.98Å; T25-Q167 PolarHBondContact OG1-NE2 3.43Å; T25-Q167 VanDerWaalsContact OG1-NE2 3.07Å
26	L	94.1	Very high	94.3	Very high	34 Å²	34	21.2 Å²	21.2	18%	0.178	11%	0.108	C	C	.	.	H	α-helix	trans	-108.7	-19.5	-177.4	-69.2	-168.6	0	0	0	114.1	L23 P28 W29 N30 Q167 A170	L23-L26 PolarHBondContact O-N 3.17Å; L26-P28 VanDerWaalsContact C-CD 3.44Å; L26-W29 PolarHBondContact O-N 3.4Å; L26-N30 WeakPolarHBondContact O-CB 3.04Å; L26-N30 VanDerWaalsContact O-CG 3.27Å; L26-N30 PolarHBondContact O-N 3.04Å; L26-Q167 HydrophobicContact CD1-CB 3.63Å; L26-Q167 HydrophobicContact CD1-CG 3.86Å; L26-Q167 HydrophobicContact CG-CB 4.16Å; L26-Q167 HydrophobicContact CG-CG 3.9Å; L26-A170 HydrophobicContact CB-CB 4.1Å
27	L	94.4	Very high	94.1	Very high	6 Å²	6	21.2 Å²	21.2	3%	0.031	11%	0.113	C	C	.	.	H	α-helix	trans	-53.4	-46.1	178.4	-165.6	74.7	0	0	0	112.8	L23 W29 N30 F31 A170 F173	L23-L27 WeakPolarHBondContact O-CB 3.36Å; L23-L27 PolarHBondContact O-N 3.14Å; L27-W29 PolarHBondContact O-N 2.77Å; L27-N30 PolarHBondContact O-N 3.13Å; L27-F31 HydrophobicContact CD1-CD2 3.85Å; L27-F31 HydrophobicContact CD1-CE2 3.48Å; L27-F31 VanDerWaalsContact CD1-CE2 3.48Å; L27-F31 HydrophobicContact CG-CD2 4.02Å; L27-F31 HydrophobicContact CG-CE2 4.05Å; L27-F31 WeakPolarHBondContact O-CB 3.47Å; L27-F31 VanDerWaalsContact O-CD2 3.28Å; L27-F31 WeakPolarHBondContact O-CD2 3.28Å; L27-F31 PolarHBondContact O-N 3.36Å; L27-F31 VanDerWaalsContact O-N 3.11Å; L27-A170 HydrophobicContact CB-CB 4.05Å; L27-A170 HydrophobicContact CD1-CB 4.03Å; L27-F173 HydrophobicContact CD1-CB 3.97Å; L27-F173 HydrophobicContact CD1-CD2 4.12Å
28	P	95.1	Very high	93.9	Very high	4 Å²	4	21.5 Å²	21.5	3%	0.026	11%	0.113	C	C	.	.	H	α-helix	trans	-62.5	-48.7	-179.1	-18.4	32.2	0	0	0	111.9	G24 L26 N30 F31 F32 I106 F110 P199 I203	G24-P28 WeakPolarHBondContact O-CD 2.95Å; L26-P28 VanDerWaalsContact C-CD 3.44Å; P28-N30 PolarHBondContact O-N 3.25Å; P28-F31 PolarHBondContact O-N 3.17Å; P28-F32 WeakPolarHBondContact O-CB 3.26Å; P28-F32 PolarHBondContact O-N 3.5Å; P28-I106 HydrophobicContact CB-CG2 4.2Å; P28-I106 HydrophobicContact CG-CG2 4.18Å; P28-F110 HydrophobicContact CB-CD1 4.3Å; P28-F110 HydrophobicContact CB-CD2 3.9Å; P28-F110 HydrophobicContact CB-CE1 3.78Å; P28-F110 HydrophobicContact CB-CE2 3.32Å; P28-F110 HydrophobicContact CB-CG 4.37Å; P28-F110 HydrophobicContact CB-CZ 3.28Å; P28-F110 WeakPolarHBondContact O-CE1 3.48Å; P28-F110 WeakPolarHBondContact O-CZ 3.11Å; P28-P199 HydrophobicContact CB-CB 3.96Å; P28-P199 HydrophobicContact CG-CB 4.06Å; P28-I203 HydrophobicContact CB-CD1 4.41Å; P28-I203 HydrophobicContact CG-CD1 3.7Å; P28-I203 HydrophobicContact CG-CG1 3.89Å
29	W	94.6	Very high	93.7	Very high	46 Å²	46	21.6 Å²	21.6	17%	0.174	11%	0.113	C	C	.	.	H	α-helix	trans	-64.9	-41.5	-178.8	-177	-120	0	0	0	112.8	L26 L27 F31 F32 I33 V71 S75 V134	L26-W29 PolarHBondContact O-N 3.4Å; L27-W29 PolarHBondContact O-N 2.77Å; W29-F31 VanDerWaalsContact C-N 3.33Å; W29-F31 PolarHBondContact O-N 3.27Å; W29-F32 HydrophobicContact CE3-CB 4.24Å; W29-F32 HydrophobicContact CE3-CD1 4.29Å; W29-F32 HydrophobicContact CE3-CG 4.41Å; W29-F32 HydrophobicContact CH2-CD1 4.45Å; W29-F32 AromaticContact CZ3-CD1 3.78Å; W29-F32 HydrophobicContact CZ3-CD1 3.78Å; W29-F32 HydrophobicContact CZ3-CE1 4.34Å; W29-F32 HydrophobicContact CZ3-CG 4.29Å; W29-F32 WeakPolarHBondContact O-CB 2.93Å; W29-F32 PolarHBondContact O-N 3.27Å; W29-I33 HydrophobicContact CD2-CD1 4.28Å; W29-I33 HydrophobicContact CD2-CG1 4.35Å; W29-I33 HydrophobicContact CG-CD1 4.39Å; W29-I33 HydrophobicContact CZ2-CD1 3.97Å; W29-I33 HydrophobicContact CZ2-CG1 4.02Å; W29-I33 VanDerWaalsContact NE1-CD1 3.32Å; W29-I33 WeakPolarHBondContact O-CG1 2.99Å; W29-I33 PolarHBondContact O-N 2.93Å; W29-V71 HydrophobicContact CH2-CG1 3.86Å; W29-S75 VanDerWaalsContact CZ2-CB 3.43Å; W29-V134 HydrophobicContact CH2-CG1 4.32Å; W29-V134 HydrophobicContact CZ3-CG1 4.17Å
30	N	95.3	Very high	93.4	Very high	33 Å²	33	22.1 Å²	22.1	18%	0.176	12%	0.117	C	C	.	.	H	α-helix	trans	-63.4	-39.8	178.5	-71.2	-10.2	0	0	0	112.1	L26 L27 P28 T34 G171 A174	L26-N30 WeakPolarHBondContact O-CB 3.04Å; L26-N30 VanDerWaalsContact O-CG 3.27Å; L26-N30 PolarHBondContact O-N 3.04Å; L27-N30 PolarHBondContact O-N 3.13Å; P28-N30 PolarHBondContact O-N 3.25Å; N30-T34 WeakPolarHBondContact O-CB 3.2Å; N30-T34 PolarHBondContact O-N 3.33Å; N30-T34 PolarHBondContact O-OG1 3.26Å; N30-G171 VanDerWaalsContact ND2-CA 3.29Å; N30-G171 WeakPolarHBondContact ND2-CA 3.32Å; N30-G171 PolarHBondContact ND2-N 3.37Å; N30-G171 VanDerWaalsContact ND2-N 3.19Å; N30-A174 HydrophobicContact CB-CB 3.66Å
31	F	95.2	Very high	92.9	Very high	4 Å²	4	23.2 Å²	23.2	2%	0.018	13%	0.131	C	C	.	.	H	α-helix	trans	-70.5	-35.2	174.7	-88.6	-102.4	0	0	0	112.5	L27 P28 W29 T34 A35 F173 A174 A177 Y195 T198 P199	L27-F31 HydrophobicContact CD1-CD2 3.85Å; L27-F31 HydrophobicContact CD1-CE2 3.48Å; L27-F31 VanDerWaalsContact CD1-CE2 3.48Å; L27-F31 HydrophobicContact CG-CD2 4.02Å; L27-F31 HydrophobicContact CG-CE2 4.05Å; L27-F31 WeakPolarHBondContact O-CB 3.47Å; L27-F31 VanDerWaalsContact O-CD2 3.28Å; L27-F31 WeakPolarHBondContact O-CD2 3.28Å; L27-F31 PolarHBondContact O-N 3.36Å; L27-F31 VanDerWaalsContact O-N 3.11Å; P28-F31 PolarHBondContact O-N 3.17Å; W29-F31 VanDerWaalsContact C-N 3.33Å; W29-F31 PolarHBondContact O-N 3.27Å; F31-T34 WeakPolarHBondContact O-CB 3.28Å; F31-T34 PolarHBondContact O-N 3.21Å; F31-A35 PolarHBondContact O-N 2.93Å; F31-F173 HydrophobicContact CE2-CB 4.11Å; F31-F173 HydrophobicContact CZ-CB 4.44Å; F31-A174 HydrophobicContact CD2-CB 3.84Å; F31-A174 HydrophobicContact CE2-CB 3.93Å; F31-A177 HydrophobicContact CE1-CB 3.54Å; F31-A177 HydrophobicContact CZ-CB 3.68Å; F31-Y195 WeakPolarHBondContact CB-O 3.49Å; F31-Y195 AromaticContact CD1-CD1 3.87Å; F31-Y195 HydrophobicContact CD1-CD1 3.87Å; F31-Y195 HydrophobicContact CD1-CG 4.25Å; F31-Y195 VanDerWaalsContact CD1-O 3.32Å; F31-Y195 WeakPolarHBondContact CD1-O 3.26Å; F31-Y195 HydrophobicContact CE1-CD1 4.02Å; F31-T198 HydrophobicContact CE1-CG2 4.07Å; F31-T198 HydrophobicContact CZ-CG2 3.87Å; F31-P199 HydrophobicContact CB-CG 3.62Å; F31-P199 HydrophobicContact CD1-CG 4.29Å; F31-P199 HydrophobicContact CD2-CG 4.23Å; F31-P199 HydrophobicContact CG-CG 3.78Å
32	F	94.9	Very high	92.4	Very high	0 Å²	0	25.1 Å²	25.1	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-61	-47	173	-169.6	-80.4	0	0	0	111.6	P28 W29 T34 A35 I36 F39 V71 F110 T113 T130 V134 F196	P28-F32 WeakPolarHBondContact O-CB 3.26Å; P28-F32 PolarHBondContact O-N 3.5Å; W29-F32 HydrophobicContact CE3-CB 4.24Å; W29-F32 HydrophobicContact CE3-CD1 4.29Å; W29-F32 HydrophobicContact CE3-CG 4.41Å; W29-F32 HydrophobicContact CH2-CD1 4.45Å; W29-F32 AromaticContact CZ3-CD1 3.78Å; W29-F32 HydrophobicContact CZ3-CD1 3.78Å; W29-F32 HydrophobicContact CZ3-CE1 4.34Å; W29-F32 HydrophobicContact CZ3-CG 4.29Å; W29-F32 WeakPolarHBondContact O-CB 2.93Å; W29-F32 PolarHBondContact O-N 3.27Å; F32-T34 VanDerWaalsContact C-N 3.3Å; F32-T34 PolarHBondContact O-N 3.12Å; F32-A35 PolarHBondContact O-N 3.27Å; F32-A35 VanDerWaalsContact O-N 3.1Å; F32-I36 PolarHBondContact O-N 3.01Å; F32-F39 HydrophobicContact CD2-CE2 4.27Å; F32-F39 HydrophobicContact CD2-CZ 4.32Å; F32-F39 HydrophobicContact CE1-CE2 4.06Å; F32-F39 AromaticContact CE2-CE2 3.79Å; F32-F39 HydrophobicContact CE2-CE2 3.79Å; F32-F39 AromaticContact CE2-CZ 3.6Å; F32-F39 HydrophobicContact CE2-CZ 3.6Å; F32-F39 HydrophobicContact CZ-CD2 4.45Å; F32-F39 AromaticContact CZ-CE2 3.66Å; F32-F39 HydrophobicContact CZ-CE2 3.66Å; F32-F39 AromaticContact CZ-CZ 3.74Å; F32-F39 HydrophobicContact CZ-CZ 3.74Å; F32-V71 HydrophobicContact CE1-CG1 4.39Å; F32-F110 HydrophobicContact CB-CE1 4.48Å; F32-F110 HydrophobicContact CB-CZ 4.13Å; F32-F110 HydrophobicContact CD2-CZ 4.41Å; F32-T113 HydrophobicContact CE2-CG2 4.49Å; F32-T130 HydrophobicContact CZ-CG2 3.96Å; F32-V134 HydrophobicContact CD1-CG2 4.5Å; F32-V134 HydrophobicContact CE1-CG2 3.56Å; F32-V134 HydrophobicContact CE2-CG2 3.94Å; F32-V134 HydrophobicContact CZ-CG2 3.22Å; F32-F196 HydrophobicContact CD2-CE1 4.07Å
33	I	91.5	Very high	91.9	Very high	60 Å²	60	25.5 Å²	25.5	31%	0.308	14%	0.14	S	C	.	.	H	α-helix	trans	-59.4	-43.5	174.8	-69.3	171.3	0	0	0	110.6	W29 A35 I36	W29-I33 HydrophobicContact CD2-CD1 4.28Å; W29-I33 HydrophobicContact CD2-CG1 4.35Å; W29-I33 HydrophobicContact CG-CD1 4.39Å; W29-I33 HydrophobicContact CZ2-CD1 3.97Å; W29-I33 HydrophobicContact CZ2-CG1 4.02Å; W29-I33 VanDerWaalsContact NE1-CD1 3.32Å; W29-I33 WeakPolarHBondContact O-CG1 2.99Å; W29-I33 PolarHBondContact O-N 2.93Å; I33-A35 PolarHBondContact O-N 3.44Å; I33-I36 HydrophobicContact CB-CD1 4.34Å; I33-I36 HydrophobicContact CG2-CD1 3.99Å; I33-I36 VanDerWaalsContact O-CB 3.3Å; I33-I36 WeakPolarHBondContact O-CB 3.2Å; I33-I36 WeakPolarHBondContact O-CD1 3.28Å; I33-I36 WeakPolarHBondContact O-CG1 3.32Å; I33-I36 PolarHBondContact O-N 2.93Å
34	T	91.8	Very high	91.2	Very high	23 Å²	23	27.2 Å²	27.2	14%	0.141	15%	0.151	C	C	.	.	H	α-helix	trans	-61	-29.6	178.1	-58.5	0	0	0	0	112.1	N30 F31 F32 P37 M178 Y195	N30-T34 WeakPolarHBondContact O-CB 3.2Å; N30-T34 PolarHBondContact O-N 3.33Å; N30-T34 PolarHBondContact O-OG1 3.26Å; F31-T34 WeakPolarHBondContact O-CB 3.28Å; F31-T34 PolarHBondContact O-N 3.21Å; F32-T34 VanDerWaalsContact C-N 3.3Å; F32-T34 PolarHBondContact O-N 3.12Å; T34-P37 WeakPolarHBondContact O-CD 3.28Å; T34-M178 HydrophobicContact CG2-CB 3.62Å; T34-M178 HydrophobicContact CG2-CG 4.03Å; T34-M178 HydrophobicContact CG2-SD 4.46Å; T34-Y195 HydrophobicContact CG2-CE1 4.23Å; T34-Y195 HydrophobicContact CG2-CE2 4.12Å
35	A	92.2	Very high	89.7	Confident	0 Å²	0	29.2 Å²	29.2	0%	0	17%	0.172	C	C	.	.	T	Hydrogen-bonded Turn	trans	-84.3	1.6	177.1	0	0	0	0	0	114.4	F31 F32 I33 P37 Y38 F39 Y195 F196	F31-A35 PolarHBondContact O-N 2.93Å; F32-A35 PolarHBondContact O-N 3.27Å; F32-A35 VanDerWaalsContact O-N 3.1Å; I33-A35 PolarHBondContact O-N 3.44Å; A35-P37 VanDerWaalsContact C-CD 3.47Å; A35-P37 VanDerWaalsContact C-N 3.35Å; A35-Y38 VanDerWaalsContact O-CB 3.29Å; A35-Y38 WeakPolarHBondContact O-CB 3.15Å; A35-Y38 PolarHBondContact O-N 2.84Å; A35-F39 HydrophobicContact CB-CD2 4.47Å; A35-F39 HydrophobicContact CB-CE2 4.1Å; A35-F39 VanDerWaalsContact O-CD2 3.27Å; A35-F39 WeakPolarHBondContact O-CD2 3.45Å; A35-F39 PolarHBondContact O-N 2.89Å; A35-Y195 HydrophobicContact CB-CD2 3.88Å; A35-F196 HydrophobicContact CB-CE1 3.97Å; A35-F196 HydrophobicContact CB-CE2 4.49Å; A35-F196 HydrophobicContact CB-CZ 3.62Å
36	I	90.5	Very high	87.7	Confident	28 Å²	28	30.9 Å²	30.9	14%	0.144	19%	0.187	C	C	.	.	H	α-helix	trans	-50.7	-46	178.1	-73.6	169.9	0	0	0	113	F32 I33 Y38 F39 Q40 F67 N68	F32-I36 PolarHBondContact O-N 3.01Å; I33-I36 HydrophobicContact CB-CD1 4.34Å; I33-I36 HydrophobicContact CG2-CD1 3.99Å; I33-I36 VanDerWaalsContact O-CB 3.3Å; I33-I36 WeakPolarHBondContact O-CB 3.2Å; I33-I36 WeakPolarHBondContact O-CD1 3.28Å; I33-I36 WeakPolarHBondContact O-CG1 3.32Å; I33-I36 PolarHBondContact O-N 2.93Å; I36-Y38 PolarHBondContact O-N 3.43Å; I36-F39 PolarHBondContact O-N 3.37Å; I36-F39 VanDerWaalsContact O-N 3.08Å; I36-Q40 HydrophobicContact CG2-CG 4.25Å; I36-Q40 WeakPolarHBondContact O-CG 3.42Å; I36-Q40 PolarHBondContact O-N 3.06Å; I36-F67 HydrophobicContact CG1-CE1 4.31Å; I36-F67 HydrophobicContact CG2-CD1 4.39Å; I36-F67 HydrophobicContact CG2-CE1 4.28Å; I36-N68 VanDerWaalsContact CG2-OD1 3.25Å; I36-N68 WeakPolarHBondContact CG2-OD1 3.43Å
37	P	87.8	Confident	85.7	Confident	84 Å²	84	31.3 Å²	31.3	55%	0.545	19%	0.193	S	C	.	.	H	α-helix	trans	-58.9	-32.5	178.7	-25.7	35.8	0	0	0	113.4	T34 A35 A41	T34-P37 WeakPolarHBondContact O-CD 3.28Å; A35-P37 VanDerWaalsContact C-CD 3.47Å; A35-P37 VanDerWaalsContact C-N 3.35Å; P37-A41 VanDerWaalsContact O-CB 3.3Å; P37-A41 WeakPolarHBondContact O-CB 3.2Å; P37-A41 PolarHBondContact O-N 2.92Å
38	Y	90.3	Very high	83.6	Confident	15 Å²	15	35.4 Å²	35.4	6%	0.059	21%	0.214	C	C	.	.	H	α-helix	trans	-65.1	-46.8	175.2	159.9	-94.3	0	0	0	111.5	A35 I36 Q40 A41 R42 V117 F126 A188 Q189 A192 F196	A35-Y38 VanDerWaalsContact O-CB 3.29Å; A35-Y38 WeakPolarHBondContact O-CB 3.15Å; A35-Y38 PolarHBondContact O-N 2.84Å; I36-Y38 PolarHBondContact O-N 3.43Å; Y38-Q40 PolarHBondContact O-N 3.38Å; Y38-A41 PolarHBondContact O-N 3.26Å; Y38-R42 WeakPolarHBondContact O-CB 3.39Å; Y38-R42 PolarHBondContact O-N 3.36Å; Y38-R42 WeakPolarHBondContact OH-CD 3.36Å; Y38-R42 PolarHBondContact OH-NH1 2.9Å; Y38-V117 HydrophobicContact CE1-CG2 4.05Å; Y38-V117 HydrophobicContact CE2-CG1 4.28Å; Y38-V117 WeakPolarHBondContact OH-CA 3.49Å; Y38-V117 WeakPolarHBondContact OH-CG1 3.41Å; Y38-F126 HydrophobicContact CE1-CZ 4.36Å; Y38-A188 HydrophobicContact CD2-CB 4.46Å; Y38-A188 WeakPolarHBondContact CD2-O 3.47Å; Y38-Q189 HydrophobicContact CE2-CG 4.2Å; Y38-A192 HydrophobicContact CD1-CB 3.77Å; Y38-A192 HydrophobicContact CD2-CB 3.51Å; Y38-A192 HydrophobicContact CE1-CB 4.08Å; Y38-A192 HydrophobicContact CE2-CB 3.83Å; Y38-A192 HydrophobicContact CG-CB 3.49Å; Y38-A192 VanDerWaalsContact CG-CB 3.49Å; Y38-F196 HydrophobicContact CD1-CE2 4.48Å; Y38-F196 HydrophobicContact CE1-CE2 4.4Å
39	F	91	Very high	81.3	Confident	2 Å²	2	40.3 Å²	40.3	1%	0.009	25%	0.249	C	C	.	.	H	α-helix	trans	-62.2	-43.8	178.8	-70.3	-73	0	0	0	111.8	F32 A35 I36 R42 L43 F67 T113 F126 T130 F196	F32-F39 HydrophobicContact CD2-CE2 4.27Å; F32-F39 HydrophobicContact CD2-CZ 4.32Å; F32-F39 HydrophobicContact CE1-CE2 4.06Å; F32-F39 AromaticContact CE2-CE2 3.79Å; F32-F39 HydrophobicContact CE2-CE2 3.79Å; F32-F39 AromaticContact CE2-CZ 3.6Å; F32-F39 HydrophobicContact CE2-CZ 3.6Å; F32-F39 HydrophobicContact CZ-CD2 4.45Å; F32-F39 AromaticContact CZ-CE2 3.66Å; F32-F39 HydrophobicContact CZ-CE2 3.66Å; F32-F39 AromaticContact CZ-CZ 3.74Å; F32-F39 HydrophobicContact CZ-CZ 3.74Å; A35-F39 HydrophobicContact CB-CD2 4.47Å; A35-F39 HydrophobicContact CB-CE2 4.1Å; A35-F39 VanDerWaalsContact O-CD2 3.27Å; A35-F39 WeakPolarHBondContact O-CD2 3.45Å; A35-F39 PolarHBondContact O-N 2.89Å; I36-F39 PolarHBondContact O-N 3.37Å; I36-F39 VanDerWaalsContact O-N 3.08Å; F39-R42 PolarHBondContact O-N 2.97Å; F39-L43 VanDerWaalsContact O-CG 3.3Å; F39-L43 WeakPolarHBondContact O-CG 3.42Å; F39-L43 PolarHBondContact O-N 2.91Å; F39-F67 HydrophobicContact CB-CD2 4.49Å; F39-F67 HydrophobicContact CB-CE1 3.72Å; F39-F67 HydrophobicContact CB-CE2 3.69Å; F39-F67 HydrophobicContact CB-CZ 3.26Å; F39-F67 HydrophobicContact CD1-CE2 4.46Å; F39-F67 HydrophobicContact CD1-CZ 4.19Å; F39-F67 HydrophobicContact CD2-CE1 4.34Å; F39-F67 AromaticContact CD2-CZ 3.85Å; F39-F67 HydrophobicContact CD2-CZ 3.85Å; F39-F67 HydrophobicContact CG-CE1 4.25Å; F39-F67 HydrophobicContact CG-CE2 4.14Å; F39-F67 AromaticContact CG-CZ 3.53Å; F39-F67 HydrophobicContact CG-CZ 3.53Å; F39-T113 HydrophobicContact CZ-CG2 4.1Å; F39-F126 AromaticContact CD1-CE1 3.78Å; F39-F126 HydrophobicContact CD1-CE1 3.78Å; F39-F126 AromaticContact CD1-CZ 3.5Å; F39-F126 HydrophobicContact CD1-CZ 3.5Å; F39-F126 HydrophobicContact CE1-CE1 4.47Å; F39-F126 AromaticContact CE1-CZ 3.8Å; F39-F126 HydrophobicContact CE1-CZ 3.8Å; F39-T130 HydrophobicContact CD1-CG2 3.9Å; F39-T130 HydrophobicContact CE1-CG2 3.59Å; F39-T130 HydrophobicContact CZ-CG2 4.13Å; F39-F196 HydrophobicContact CE1-CZ 4.42Å; F39-F196 HydrophobicContact CE2-CE1 4.23Å; F39-F196 AromaticContact CE2-CZ 3.63Å; F39-F196 HydrophobicContact CE2-CZ 3.63Å; F39-F196 HydrophobicContact CZ-CE1 4.09Å; F39-F196 HydrophobicContact CZ-CE2 4.21Å; F39-F196 AromaticContact CZ-CZ 3.4Å; F39-F196 HydrophobicContact CZ-CZ 3.4Å; F39-F196 VanDerWaalsContact CZ-CZ 3.4Å
40	Q	88.1	Confident	79	Confident	61 Å²	61	43.5 Å²	43.5	29%	0.285	27%	0.274	S	S	.	.	H	α-helix	trans	-62.4	-48.4	177.7	-67.1	-177.4	-54.3	0	0	111.6	I36 Y38 R42 L43 V44 F67 N68	I36-Q40 HydrophobicContact CG2-CG 4.25Å; I36-Q40 WeakPolarHBondContact O-CG 3.42Å; I36-Q40 PolarHBondContact O-N 3.06Å; Y38-Q40 PolarHBondContact O-N 3.38Å; Q40-R42 VanDerWaalsContact C-N 3.28Å; Q40-R42 PolarHBondContact O-N 3.02Å; Q40-L43 PolarHBondContact O-N 3.34Å; Q40-V44 WeakPolarHBondContact O-CG2 3.14Å; Q40-V44 PolarHBondContact O-N 3.02Å; Q40-F67 HydrophobicContact CG-CD1 4.16Å; Q40-N68 PolarHBondContact NE2-ND2 3.39Å
41	A	86.1	Confident	76.6	Confident	62 Å²	62	45.4 Å²	45.4	51%	0.512	29%	0.287	S	S	.	.	H	α-helix	trans	-60	-39.6	178.2	0	0	0	0	0	111.9	P37 Y38 G45	P37-A41 VanDerWaalsContact O-CB 3.3Å; P37-A41 WeakPolarHBondContact O-CB 3.2Å; P37-A41 PolarHBondContact O-N 2.92Å; Y38-A41 PolarHBondContact O-N 3.26Å; A41-G45 PolarHBondContact O-N 3.08Å
42	R	86.6	Confident	74.1	Confident	42 Å²	42	56.3 Å²	56.3	16%	0.158	33%	0.328	C	S	.	.	H	α-helix	trans	-67.1	-38.5	178.1	-179.1	162.4	177.4	162.8	6.6	113.1	Y38 F39 Q40 L116 V117 V119 F126	Y38-R42 WeakPolarHBondContact O-CB 3.39Å; Y38-R42 PolarHBondContact O-N 3.36Å; Y38-R42 WeakPolarHBondContact OH-CD 3.36Å; Y38-R42 PolarHBondContact OH-NH1 2.9Å; F39-R42 PolarHBondContact O-N 2.97Å; Q40-R42 VanDerWaalsContact C-N 3.28Å; Q40-R42 PolarHBondContact O-N 3.02Å; R42-L116 PolarHBondContact NH1-O 3.3Å; R42-L116 PolarHBondContact NH2-O 3.41Å; R42-V117 PolarHBondContact NH1-O 3.37Å; R42-V119 PolarHBondContact NH2-O 2.76Å; R42-F126 HydrophobicContact CB-CE1 4.21Å; R42-F126 VanDerWaalsContact CD-CZ 3.48Å; R42-F126 HydrophobicContact CG-CD1 4.22Å; R42-F126 HydrophobicContact CG-CE1 3.87Å; R42-F126 HydrophobicContact CG-CZ 4.21Å
43	L	85.8	Confident	71.8	Confident	7 Å²	7	63.5 Å²	63.5	4%	0.037	36%	0.364	C	S	.	.	H	α-helix	trans	-69.9	-38.3	177.5	-71.3	167.9	0	0	0	112.2	F39 Q40 F65 F67 P123 F126 F127	F39-L43 VanDerWaalsContact O-CG 3.3Å; F39-L43 WeakPolarHBondContact O-CG 3.42Å; F39-L43 PolarHBondContact O-N 2.91Å; Q40-L43 PolarHBondContact O-N 3.34Å; L43-F65 HydrophobicContact CB-CD2 4.26Å; L43-F65 HydrophobicContact CD2-CD2 4.34Å; L43-F65 HydrophobicContact CD2-CE2 4.35Å; L43-F67 HydrophobicContact CD1-CB 4.44Å; L43-F67 HydrophobicContact CD1-CD2 3.49Å; L43-F67 VanDerWaalsContact CD1-CD2 3.49Å; L43-F67 HydrophobicContact CD1-CE2 4.07Å; L43-F67 HydrophobicContact CD1-CG 4.23Å; L43-P123 HydrophobicContact CD2-CB 4.16Å; L43-P123 WeakPolarHBondContact CD2-O 3.42Å; L43-F126 HydrophobicContact CD2-CD1 3.8Å; L43-F126 HydrophobicContact CD2-CE1 4.48Å; L43-F126 HydrophobicContact CG-CD1 4.22Å; L43-F126 HydrophobicContact CG-CE1 4.43Å; L43-F127 HydrophobicContact CD1-CD2 4Å; L43-F127 HydrophobicContact CD2-CB 3.9Å
44	V	79.8	Confident	69.6	Low	51 Å²	51	68.1 Å²	68.1	31%	0.309	39%	0.389	S	S	.	.	H	α-helix	trans	-73.3	-44.3	177.7	174.4	0	0	0	0	111.8	Q40 A46 S47 N48	Q40-V44 WeakPolarHBondContact O-CG2 3.14Å; Q40-V44 PolarHBondContact O-N 3.02Å; V44-A46 PolarHBondContact O-N 3.49Å; V44-A46 VanDerWaalsContact O-N 3.16Å; V44-S47 PolarHBondContact O-N 3.12Å; V44-N48 PolarHBondContact O-N 3.26Å
45	G	63.5	Low	67	Low	46 Å²	46	71.7 Å²	71.7	47%	0.474	42%	0.415	S	S	.	.	H	α-helix	trans	-58.6	-30.4	-175.4	0	0	0	0	0	114.4	A41	A41-G45 PolarHBondContact O-N 3.08Å
46	A	54.2	Low	64.6	Low	41 Å²	41	78 Å²	78	34%	0.339	45%	0.453	S	S	.	.	H	α-helix	trans	-93	-11.2	177.9	0	0	0	0	0	114.1	V44 P123	V44-A46 PolarHBondContact O-N 3.49Å; V44-A46 VanDerWaalsContact O-N 3.16Å; A46-P123 HydrophobicContact CB-CG 3.43Å; A46-P123 VanDerWaalsContact CB-CG 3.43Å
47	S	50.3	Low	62.4	Low	43 Å²	43	83.4 Å²	83.4	30%	0.301	48%	0.483	S	S	.	.	H	α-helix	trans	-82.2	-26.9	170.1	-166.3	0	0	0	0	112.7	V44 S49 T50 T51	V44-S47 PolarHBondContact O-N 3.12Å; S47-S49 PolarHBondContact O-N 3.3Å; S47-T50 PolarHBondContact O-N 2.84Å; S47-T51 PolarHBondContact O-N 2.9Å; S47-T51 PolarHBondContact O-OG1 3.22Å
48	N	51.5	Low	59.9	Low	91 Å²	91	88.2 Å²	88.2	49%	0.487	50%	0.498	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.1	-11.3	-178.3	-73.9	-11.2	0	0	0	114.5	V44 T50	V44-N48 PolarHBondContact O-N 3.26Å; N48-T50 VanDerWaalsContact C-N 3.31Å
49	S	46.9	Very low	57.6	Low	107 Å²	107	94.1 Å²	94.1	75%	0.748	54%	0.535	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76	-18	174.2	-53.9	0	0	0	0	113.1	S47	S47-S49 PolarHBondContact O-N 3.3Å
50	T	46.1	Very low	55.3	Low	114 Å²	114	96.7 Å²	96.7	70%	0.699	56%	0.563	S	S	*	*	T	Hydrogen-bonded Turn	trans	-118.7	-26	-174.3	-17.4	0	0	0	0	113.2	S47 N48	S47-T50 PolarHBondContact O-N 2.84Å; N48-T50 VanDerWaalsContact C-N 3.31Å
51	T	44.3	Very low	53.3	Low	73 Å²	73	99.4 Å²	99.4	45%	0.448	59%	0.585	S	S	.	*	S	Bend	trans	-97.6	5.5	-171.2	-41.2	0	0	0	0	114.6	S47 I53	S47-T51 PolarHBondContact O-N 2.9Å; S47-T51 PolarHBondContact O-OG1 3.22Å; T51-I53 PolarHBondContact O-N 2.75Å
52	R	42.4	Very low	51.7	Low	232 Å²	232	104 Å²	104	88%	0.875	60%	0.596	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.4	6.2	178.6	-144.6	-171.6	-109.3	151.3	-4.3	114.3
53	I	46.6	Very low	50.6	Low	151 Å²	151	104.8 Å²	104.8	77%	0.774	60%	0.604	S	S	*	*	T	Hydrogen-bonded Turn	trans	-105.6	-10.4	-176.2	-51.8	-176.5	0	0	0	113.2	T51	T51-I53 PolarHBondContact O-N 2.75Å
54	L	45.9	Very low	49.4	Very low	157 Å²	157	108 Å²	108	82%	0.822	63%	0.632	S	S	*	*	S	Bend	trans	-145.6	17.6	-165.8	-107.7	139.7	0	0	0	120.7
55	S	37.6	Very low	48.9	Very low	98 Å²	98	108.5 Å²	108.5	69%	0.685	63%	0.63	S	S	*	*			trans	-147.5	89	169.9	48.3	0	0	0	0	113.7
56	T	41.9	Very low	49.8	Very low	132 Å²	132	110.2 Å²	110.2	81%	0.81	63%	0.628	S	S	*	*			trans	-83.3	132.6	155.1	38.8	0	0	0	0	108.9
57	N	43.6	Very low	51.4	Low	142 Å²	142	108.3 Å²	108.3	76%	0.759	61%	0.612	S	S	*	*	S	Bend	trans	81.3	83.3	174.8	-53.1	-20.3	0	0	0	115.9
58	H	35.4	Very low	53.1	Low	185 Å²	185	108.7 Å²	108.7	86%	0.856	61%	0.611	S	S	*	*				-171.2	157.5	124.9	-88.9	-57.2	0	0	0	110.4
59	T	42.3	Very low	54.8	Low	139 Å²	139	107.5 Å²	107.5	85%	0.853	61%	0.605	S	S	*	*			trans	-79.2	129.9	-160.8	41	0	0	0	0	114.8
60	G	41.4	Very low	56.9	Low	57 Å²	57	108 Å²	108	59%	0.588	59%	0.59	S	S	*	*	S	Bend	trans	92.9	151.3	168.6	0	0	0	0	0	114.5	E62	G60-E62 PolarHBondContact O-N 2.79Å
61	P	47.2	Very low	59	Low	117 Å²	117	102.8 Å²	102.8	76%	0.76	56%	0.558	S	S	*	*			trans	-64.3	109.3	172.4	25.8	-30	0	0	0	108.7	D63	P61-D63 PolarHBondContact O-N 3.28Å
62	E	52.4	Low	61.2	Low	158 Å²	158	101.3 Å²	101.3	74%	0.738	55%	0.549	S	S	*	.			trans	-58.5	123.8	174.2	-68.6	-174.8	158.2	0	0	109.3	G60 A64	G60-E62 PolarHBondContact O-N 2.79Å; E62-A64 PolarHBondContact O-N 2.98Å
63	D	62.8	Low	63.5	Low	60 Å²	60	94.5 Å²	94.5	32%	0.321	53%	0.53	S	S	.	.			trans	-71.5	72.5	169.9	-173.9	5	0	0	0	108.5	P61 F65 N66 F67	P61-D63 PolarHBondContact O-N 3.28Å; D63-F65 PolarHBondContact O-N 2.88Å; D63-N66 PolarHBondContact O-N 2.83Å; D63-N66 PolarHBondContact OD1-N 3.25Å; D63-N66 VanDerWaalsContact OD1-N 3.17Å; D63-N66 WeakPolarHBondContact OD2-CA 3.13Å; D63-F67 PolarHBondContact OD1-N 2.84Å; D63-F67 PolarHBondContact OD2-N 3.04Å; D63-F67 VanDerWaalsContact OD2-N 3.12Å
64	A	60.2	Low	65.7	Low	75 Å²	75	89.1 Å²	89.1	62%	0.62	50%	0.502	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.2	-24.8	-173.1	0	0	0	0	0	113.2	E62	E62-A64 PolarHBondContact O-N 2.98Å
65	F	70.3	Confident	67.9	Low	60 Å²	60	81.8 Å²	81.8	26%	0.263	46%	0.464	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102.3	-3.3	-179.8	-71.1	-83.5	0	0	0	113.9	L43 D63 F67 W70 P123 F127	L43-F65 HydrophobicContact CB-CD2 4.26Å; L43-F65 HydrophobicContact CD2-CD2 4.34Å; L43-F65 HydrophobicContact CD2-CE2 4.35Å; D63-F65 PolarHBondContact O-N 2.88Å; F65-F67 PolarHBondContact O-N 3.34Å; F65-W70 VanDerWaalsContact O-CD1 3.25Å; F65-P123 HydrophobicContact CE2-CB 4.23Å; F65-P123 HydrophobicContact CZ-CB 4.11Å; F65-F127 HydrophobicContact CB-CD2 3.86Å; F65-F127 HydrophobicContact CB-CE2 3.68Å; F65-F127 HydrophobicContact CB-CZ 4.29Å; F65-F127 HydrophobicContact CD1-CB 4.26Å; F65-F127 HydrophobicContact CD1-CD1 4.07Å; F65-F127 AromaticContact CD1-CD2 3.91Å; F65-F127 HydrophobicContact CD1-CD2 3.91Å; F65-F127 HydrophobicContact CD1-CE1 4.4Å; F65-F127 HydrophobicContact CD1-CE2 4.25Å; F65-F127 AromaticContact CD1-CG 3.81Å; F65-F127 HydrophobicContact CD1-CG 3.81Å; F65-F127 HydrophobicContact CD1-CZ 4.49Å; F65-F127 HydrophobicContact CE1-CB 4.37Å; F65-F127 HydrophobicContact CE1-CG 4.35Å; F65-F127 HydrophobicContact CG-CD2 4.03Å; F65-F127 HydrophobicContact CG-CE2 4.3Å; F65-F127 HydrophobicContact CG-CG 4.37Å
66	N	82.7	Confident	70.4	Confident	83 Å²	83	78.2 Å²	78.2	44%	0.444	44%	0.437	S	S	.	.			trans	47.4	45.4	-170.7	-70	-78	0	0	0	111.7	D63 N68 N69 W70	D63-N66 PolarHBondContact O-N 2.83Å; D63-N66 PolarHBondContact OD1-N 3.25Å; D63-N66 VanDerWaalsContact OD1-N 3.17Å; D63-N66 WeakPolarHBondContact OD2-CA 3.13Å; N66-N68 VanDerWaalsContact C-N 3.31Å; N66-N68 PolarHBondContact O-N 3.01Å; N66-N69 HydrophobicContact CB-CB 4.27Å; N66-N69 WeakPolarHBondContact O-CB 3.46Å; N66-N69 PolarHBondContact O-N 2.99Å; N66-W70 PolarHBondContact O-N 3.17Å; N66-W70 VanDerWaalsContact O-N 3.1Å
67	F	86.8	Confident	72.8	Confident	0 Å²	0	76.9 Å²	76.9	0%	0	42%	0.424	C	S	.	.	H	α-helix	trans	-55	-45.9	-166	-179.7	-92.7	0	0	0	112.1	I36 F39 Q40 L43 D63 F65 N69 W70 V71 F127 T130 M131	I36-F67 HydrophobicContact CG1-CE1 4.31Å; I36-F67 HydrophobicContact CG2-CD1 4.39Å; I36-F67 HydrophobicContact CG2-CE1 4.28Å; F39-F67 HydrophobicContact CB-CD2 4.49Å; F39-F67 HydrophobicContact CB-CE1 3.72Å; F39-F67 HydrophobicContact CB-CE2 3.69Å; F39-F67 HydrophobicContact CB-CZ 3.26Å; F39-F67 HydrophobicContact CD1-CE2 4.46Å; F39-F67 HydrophobicContact CD1-CZ 4.19Å; F39-F67 HydrophobicContact CD2-CE1 4.34Å; F39-F67 AromaticContact CD2-CZ 3.85Å; F39-F67 HydrophobicContact CD2-CZ 3.85Å; F39-F67 HydrophobicContact CG-CE1 4.25Å; F39-F67 HydrophobicContact CG-CE2 4.14Å; F39-F67 AromaticContact CG-CZ 3.53Å; F39-F67 HydrophobicContact CG-CZ 3.53Å; Q40-F67 HydrophobicContact CG-CD1 4.16Å; L43-F67 HydrophobicContact CD1-CB 4.44Å; L43-F67 HydrophobicContact CD1-CD2 3.49Å; L43-F67 VanDerWaalsContact CD1-CD2 3.49Å; L43-F67 HydrophobicContact CD1-CE2 4.07Å; L43-F67 HydrophobicContact CD1-CG 4.23Å; D63-F67 PolarHBondContact OD1-N 2.84Å; D63-F67 PolarHBondContact OD2-N 3.04Å; D63-F67 VanDerWaalsContact OD2-N 3.12Å; F65-F67 PolarHBondContact O-N 3.34Å; F67-N69 VanDerWaalsContact C-N 3.31Å; F67-N69 PolarHBondContact O-N 3.25Å; F67-W70 PolarHBondContact O-N 2.8Å; F67-V71 HydrophobicContact CD1-CG2 3.91Å; F67-V71 HydrophobicContact CD2-CG2 4.47Å; F67-V71 HydrophobicContact CE1-CG2 3.49Å; F67-V71 VanDerWaalsContact CE1-CG2 3.49Å; F67-V71 HydrophobicContact CE2-CG2 4.12Å; F67-V71 HydrophobicContact CG-CG2 4.38Å; F67-V71 HydrophobicContact CZ-CG2 3.6Å; F67-V71 WeakPolarHBondContact O-CG2 3.32Å; F67-V71 PolarHBondContact O-N 3.01Å; F67-F127 HydrophobicContact CD2-CD2 4.08Å; F67-F127 HydrophobicContact CD2-CE2 4.03Å; F67-T130 HydrophobicContact CE2-CG2 4.35Å; F67-M131 HydrophobicContact CD2-CE 3.25Å; F67-M131 HydrophobicContact CE2-CE 3.2Å; F67-M131 HydrophobicContact CG-CE 4.09Å; F67-M131 HydrophobicContact CZ-CE 3.99Å
68	N	86.4	Confident	75.1	Confident	51 Å²	51	70.4 Å²	70.4	27%	0.273	39%	0.389	S	S	.	.	H	α-helix	trans	-63.6	-37	-179	-67.8	-46.5	0	0	0	112.7	I36 Q40 N66 T72	I36-N68 VanDerWaalsContact CG2-OD1 3.25Å; I36-N68 WeakPolarHBondContact CG2-OD1 3.43Å; Q40-N68 PolarHBondContact NE2-ND2 3.39Å; N66-N68 VanDerWaalsContact C-N 3.31Å; N66-N68 PolarHBondContact O-N 3.01Å; N68-T72 WeakPolarHBondContact O-CB 3.27Å; N68-T72 PolarHBondContact O-N 2.89Å; N68-T72 PolarHBondContact O-OG1 3.37Å
69	N	87.6	Confident	77.8	Confident	67 Å²	67	62.1 Å²	62.1	36%	0.358	35%	0.351	S	S	.	.	H	α-helix	trans	-69.2	-44.2	-179.5	-58.1	-9.1	0	0	0	109.9	N66 F67 T72 L73 F450	N66-N69 HydrophobicContact CB-CB 4.27Å; N66-N69 WeakPolarHBondContact O-CB 3.46Å; N66-N69 PolarHBondContact O-N 2.99Å; F67-N69 VanDerWaalsContact C-N 3.31Å; F67-N69 PolarHBondContact O-N 3.25Å; N69-T72 PolarHBondContact O-N 2.97Å; N69-L73 WeakPolarHBondContact O-CB 3.43Å; N69-L73 PolarHBondContact O-N 3.06Å; N69-F450 HydrophobicContact CB-CE1 4.46Å; N69-F450 WeakPolarHBondContact OD1-CE1 3.24Å
70	W	89.9	Confident	80.2	Confident	116 Å²	116	58 Å²	58	44%	0.439	32%	0.324	S	S	.	.	H	α-helix	trans	-66.4	-44.2	176.5	-82.9	107.7	0	0	0	113	F65 N66 F67 T72 L73 L74 F127 M131	F65-W70 VanDerWaalsContact O-CD1 3.25Å; N66-W70 PolarHBondContact O-N 3.17Å; N66-W70 VanDerWaalsContact O-N 3.1Å; F67-W70 PolarHBondContact O-N 2.8Å; W70-T72 VanDerWaalsContact C-N 3.27Å; W70-T72 PolarHBondContact O-N 2.93Å; W70-L73 HydrophobicContact CE3-CD2 4.13Å; W70-L73 HydrophobicContact CZ3-CD2 3.96Å; W70-L73 PolarHBondContact O-N 3.17Å; W70-L74 HydrophobicContact CE3-CD1 4.03Å; W70-L74 HydrophobicContact CE3-CG 4.13Å; W70-L74 VanDerWaalsContact O-CB 3.27Å; W70-L74 WeakPolarHBondContact O-CB 3.5Å; W70-L74 WeakPolarHBondContact O-CG 3.31Å; W70-L74 PolarHBondContact O-N 3.4Å; W70-F127 HydrophobicContact CB-CZ 4.14Å; W70-F127 AromaticContact CD1-CZ 3.78Å; W70-F127 AromaticContact CG-CZ 3.95Å; W70-F127 HydrophobicContact CG-CZ 3.95Å; W70-M131 HydrophobicContact CB-CE 4.26Å; W70-M131 HydrophobicContact CB-SD 3.85Å
71	V	91.7	Very high	82.6	Confident	6 Å²	6	59.9 Å²	59.9	4%	0.036	32%	0.32	C	S	.	.	H	α-helix	trans	-57.9	-44.4	174.7	169.8	0	0	0	0	110.4	W29 F32 F67 S75 M131	W29-V71 HydrophobicContact CH2-CG1 3.86Å; F32-V71 HydrophobicContact CE1-CG1 4.39Å; F67-V71 HydrophobicContact CD1-CG2 3.91Å; F67-V71 HydrophobicContact CD2-CG2 4.47Å; F67-V71 HydrophobicContact CE1-CG2 3.49Å; F67-V71 VanDerWaalsContact CE1-CG2 3.49Å; F67-V71 HydrophobicContact CE2-CG2 4.12Å; F67-V71 HydrophobicContact CG-CG2 4.38Å; F67-V71 HydrophobicContact CZ-CG2 3.6Å; F67-V71 WeakPolarHBondContact O-CG2 3.32Å; F67-V71 PolarHBondContact O-N 3.01Å; V71-S75 VanDerWaalsContact O-CB 3.23Å; V71-S75 WeakPolarHBondContact O-CB 3.37Å; V71-S75 PolarHBondContact O-N 2.81Å; V71-S75 PolarHBondContact O-OG 3.37Å; V71-S75 VanDerWaalsContact O-OG 3.13Å; V71-M131 HydrophobicContact CG2-CE 3.63Å; V71-M131 HydrophobicContact CG2-SD 4.08Å
72	T	90.1	Very high	84.8	Confident	41 Å²	41	57.6 Å²	57.6	25%	0.252	30%	0.298	S	S	.	.	H	α-helix	trans	-63	-47.6	177.9	-57.3	0	0	0	0	111.3	N68 N69 W70 S75 Q76 A446 F450	N68-T72 WeakPolarHBondContact O-CB 3.27Å; N68-T72 PolarHBondContact O-N 2.89Å; N68-T72 PolarHBondContact O-OG1 3.37Å; N69-T72 PolarHBondContact O-N 2.97Å; W70-T72 VanDerWaalsContact C-N 3.27Å; W70-T72 PolarHBondContact O-N 2.93Å; T72-S75 PolarHBondContact O-N 3.5Å; T72-S75 PolarHBondContact O-OG 2.96Å; T72-Q76 HydrophobicContact CG2-CG 4.44Å; T72-Q76 VanDerWaalsContact O-CG 3.27Å; T72-Q76 WeakPolarHBondContact O-CG 3.29Å; T72-Q76 PolarHBondContact O-N 3.34Å; T72-A446 HydrophobicContact CG2-CB 3.86Å; T72-F450 HydrophobicContact CG2-CE2 4.04Å; T72-F450 HydrophobicContact CG2-CZ 4.18Å
73	L	90.3	Very high	86.5	Confident	90 Å²	90	50.1 Å²	50.1	47%	0.471	26%	0.264	S	S	.	.	H	α-helix	trans	-62.1	-48	179.5	-179.1	65.2	0	0	0	111.8	N69 W70 S75 Q76 L77	N69-L73 WeakPolarHBondContact O-CB 3.43Å; N69-L73 PolarHBondContact O-N 3.06Å; W70-L73 HydrophobicContact CE3-CD2 4.13Å; W70-L73 HydrophobicContact CZ3-CD2 3.96Å; W70-L73 PolarHBondContact O-N 3.17Å; L73-S75 VanDerWaalsContact C-N 3.29Å; L73-S75 PolarHBondContact O-N 3.31Å; L73-Q76 PolarHBondContact O-N 3.24Å; L73-L77 WeakPolarHBondContact O-CB 3.37Å; L73-L77 PolarHBondContact O-N 3.07Å
74	L	92.9	Very high	87.7	Confident	37 Å²	37	50.6 Å²	50.6	19%	0.194	27%	0.265	C	S	.	.	H	α-helix	trans	-77.6	-12.9	-176.8	-65.8	174.6	0	0	0	113.4	W70 P78 M131 V134	W70-L74 HydrophobicContact CE3-CD1 4.03Å; W70-L74 HydrophobicContact CE3-CG 4.13Å; W70-L74 VanDerWaalsContact O-CB 3.27Å; W70-L74 WeakPolarHBondContact O-CB 3.5Å; W70-L74 WeakPolarHBondContact O-CG 3.31Å; W70-L74 PolarHBondContact O-N 3.4Å; L74-P78 WeakPolarHBondContact O-CD 3.47Å; L74-P78 WeakPolarHBondContact O-CG 3.31Å; L74-M131 HydrophobicContact CD1-CB 3.55Å; L74-M131 HydrophobicContact CD1-CG 3.95Å; L74-M131 HydrophobicContact CD1-SD 3.77Å; L74-V134 HydrophobicContact CB-CG1 4.18Å
75	S	91.8	Very high	88.9	Confident	3 Å²	3	50.3 Å²	50.3	2%	0.021	25%	0.253	C	S	.	.	H	α-helix	trans	-83.5	-45.5	167.3	70.5	0	0	0	0	111.5	W29 V71 T72 L73 L79 N138	W29-S75 VanDerWaalsContact CZ2-CB 3.43Å; V71-S75 VanDerWaalsContact O-CB 3.23Å; V71-S75 WeakPolarHBondContact O-CB 3.37Å; V71-S75 PolarHBondContact O-N 2.81Å; V71-S75 PolarHBondContact O-OG 3.37Å; V71-S75 VanDerWaalsContact O-OG 3.13Å; T72-S75 PolarHBondContact O-N 3.5Å; T72-S75 PolarHBondContact O-OG 2.96Å; L73-S75 VanDerWaalsContact C-N 3.29Å; L73-S75 PolarHBondContact O-N 3.31Å; S75-L79 WeakPolarHBondContact O-CB 3.28Å; S75-L79 PolarHBondContact O-N 3.27Å; S75-N138 VanDerWaalsContact CA-CG 3.5Å; S75-N138 WeakPolarHBondContact CA-ND2 3.49Å; S75-N138 WeakPolarHBondContact O-CB 3.39Å
76	Q	91.6	Very high	89.4	Confident	24 Å²	24	47.6 Å²	47.6	11%	0.112	24%	0.242	C	C	.	.	H	α-helix	trans	-78	-42.1	-172.4	-59.3	-54.3	-2.5	0	0	113.6	T72 L73 L79 L80 A446	T72-Q76 HydrophobicContact CG2-CG 4.44Å; T72-Q76 VanDerWaalsContact O-CG 3.27Å; T72-Q76 WeakPolarHBondContact O-CG 3.29Å; T72-Q76 PolarHBondContact O-N 3.34Å; L73-Q76 PolarHBondContact O-N 3.24Å; Q76-L79 PolarHBondContact O-N 2.88Å; Q76-L80 WeakPolarHBondContact O-CB 3.25Å; Q76-L80 PolarHBondContact O-N 3.03Å; Q76-A446 HydrophobicContact CG-CB 4.18Å
77	L	91.3	Very high	89	Confident	104 Å²	104	43.8 Å²	43.8	55%	0.545	22%	0.221	S	C	.	.	H	α-helix	trans	-64.7	-47.9	-175.1	-175.1	152.2	0	0	0	112.6	L73 L79 L80 L81	L73-L77 WeakPolarHBondContact O-CB 3.37Å; L73-L77 PolarHBondContact O-N 3.07Å; L77-L79 VanDerWaalsContact C-N 3.34Å; L77-L80 PolarHBondContact O-N 3.02Å; L77-L81 WeakPolarHBondContact O-CB 3.19Å; L77-L81 PolarHBondContact O-N 3.08Å
78	P	92.2	Very high	88.3	Confident	5 Å²	5	49.4 Å²	49.4	3%	0.032	25%	0.246	C	C	.	.	H	α-helix	trans	-68	-36	176	-20	35.2	0	0	0	112	L74 L80 L81 F82 C135 S139	L74-P78 WeakPolarHBondContact O-CD 3.47Å; L74-P78 WeakPolarHBondContact O-CG 3.31Å; P78-L80 PolarHBondContact O-N 3.1Å; P78-L81 PolarHBondContact O-N 3.4Å; P78-F82 HydrophobicContact CB-CD2 4.41Å; P78-F82 WeakPolarHBondContact O-CB 3.32Å; P78-F82 WeakPolarHBondContact O-CD2 3.04Å; P78-F82 PolarHBondContact O-N 3.45Å; P78-C135 HydrophobicContact CG-CB 4.29Å; P78-C135 WeakPolarHBondContact CG-SG 3.42Å; P78-S139 VanDerWaalsContact CB-OG 3.32Å; P78-S139 WeakPolarHBondContact CB-OG 3.13Å
79	L	91.9	Very high	87.5	Confident	11 Å²	11	49.9 Å²	49.9	6%	0.058	25%	0.248	C	C	.	.	H	α-helix	trans	-58.8	-48.4	176.1	-177.4	65.6	0	0	0	111.1	S75 Q76 L77 T83 A142 A439 L442	S75-L79 WeakPolarHBondContact O-CB 3.28Å; S75-L79 PolarHBondContact O-N 3.27Å; Q76-L79 PolarHBondContact O-N 2.88Å; L77-L79 VanDerWaalsContact C-N 3.34Å; L79-T83 HydrophobicContact CD1-CG2 4.29Å; L79-T83 WeakPolarHBondContact O-CB 3.45Å; L79-T83 VanDerWaalsContact O-CG2 3.24Å; L79-T83 WeakPolarHBondContact O-CG2 3.46Å; L79-T83 PolarHBondContact O-N 2.88Å; L79-T83 PolarHBondContact O-OG1 3.43Å; L79-A142 HydrophobicContact CD1-CB 3.85Å; L79-A439 HydrophobicContact CD2-CB 4.2Å; L79-A439 HydrophobicContact CG-CB 3.86Å; L79-L442 HydrophobicContact CD2-CD1 3.9Å
80	L	92.3	Very high	86.8	Confident	53 Å²	53	48.2 Å²	48.2	28%	0.277	24%	0.237	S	C	.	.	H	α-helix	trans	-62.5	-47.2	176.8	-168.7	86.2	0	0	0	112	Q76 L77 P78 T83 L84 F436 A439 L440	Q76-L80 WeakPolarHBondContact O-CB 3.25Å; Q76-L80 PolarHBondContact O-N 3.03Å; L77-L80 PolarHBondContact O-N 3.02Å; P78-L80 PolarHBondContact O-N 3.1Å; L80-T83 PolarHBondContact O-OG1 3.19Å; L80-L84 WeakPolarHBondContact O-CB 3.5Å; L80-L84 PolarHBondContact O-N 2.94Å; L80-L84 VanDerWaalsContact O-N 3.14Å; L80-F436 HydrophobicContact CD1-CE2 4.02Å; L80-F436 HydrophobicContact CG-CE2 4.2Å; L80-A439 HydrophobicContact CD1-CB 4.46Å; L80-L440 HydrophobicContact CD1-CB 3.95Å; L80-L440 HydrophobicContact CD1-CD1 3.98Å
81	L	92.8	Very high	85.8	Confident	97 Å²	97	47.3 Å²	47.3	51%	0.508	24%	0.238	S	C	.	.	H	α-helix	trans	-64.1	-48.4	-177	179.9	66.6	0	0	0	111.7	L77 P78 L84 L85	L77-L81 WeakPolarHBondContact O-CB 3.19Å; L77-L81 PolarHBondContact O-N 3.08Å; P78-L81 PolarHBondContact O-N 3.4Å; L81-L84 PolarHBondContact O-N 3.31Å; L81-L85 VanDerWaalsContact O-CB 3.26Å; L81-L85 WeakPolarHBondContact O-CB 3.38Å; L81-L85 PolarHBondContact O-N 3.3Å
82	F	92.1	Very high	85.1	Confident	68 Å²	68	51.8 Å²	51.8	30%	0.298	27%	0.268	S	S	.	.	H	α-helix	trans	-78	-25.9	-175.6	-80.9	-90.9	0	0	0	113.1	P78 L85 N86 S139 A142 V143	P78-F82 HydrophobicContact CB-CD2 4.41Å; P78-F82 WeakPolarHBondContact O-CB 3.32Å; P78-F82 WeakPolarHBondContact O-CD2 3.04Å; P78-F82 PolarHBondContact O-N 3.45Å; F82-L85 HydrophobicContact CD1-CD2 4.5Å; F82-N86 WeakPolarHBondContact O-CB 3.36Å; F82-N86 PolarHBondContact O-N 3.27Å; F82-S139 WeakPolarHBondContact CD2-OG 3.47Å; F82-S139 VanDerWaalsContact CE2-OG 3.31Å; F82-S139 WeakPolarHBondContact CE2-OG 3.41Å; F82-A142 HydrophobicContact CB-CB 3.54Å; F82-V143 HydrophobicContact CB-CG2 4.42Å; F82-V143 HydrophobicContact CD1-CG2 4.14Å
83	T	88.9	Confident	84.8	Confident	2 Å²	2	53 Å²	53	1%	0.012	27%	0.272	C	S	.	.	H	α-helix	trans	-69.3	-41.3	170.5	48.5	0	0	0	0	111.3	L79 L80 S87 A142 T435 A439	L79-T83 HydrophobicContact CD1-CG2 4.29Å; L79-T83 WeakPolarHBondContact O-CB 3.45Å; L79-T83 VanDerWaalsContact O-CG2 3.24Å; L79-T83 WeakPolarHBondContact O-CG2 3.46Å; L79-T83 PolarHBondContact O-N 2.88Å; L79-T83 PolarHBondContact O-OG1 3.43Å; L80-T83 PolarHBondContact O-OG1 3.19Å; T83-S87 PolarHBondContact O-N 2.95Å; T83-S87 PolarHBondContact O-OG 3.13Å; T83-S87 VanDerWaalsContact O-OG 3.13Å; T83-A142 HydrophobicContact CG2-CB 3.73Å; T83-T435 HydrophobicContact CG2-CG2 3.86Å; T83-A439 HydrophobicContact CG2-CB 4.19Å
84	L	87.1	Confident	84.6	Confident	69 Å²	69	52.5 Å²	52.5	36%	0.361	27%	0.274	S	S	.	.	H	α-helix	trans	-61.2	-50.5	172.3	-178	61.7	0	0	0	110.6	L80 L81 N86 S87 F88 F436	L80-L84 WeakPolarHBondContact O-CB 3.5Å; L80-L84 PolarHBondContact O-N 2.94Å; L80-L84 VanDerWaalsContact O-N 3.14Å; L81-L84 PolarHBondContact O-N 3.31Å; L84-N86 VanDerWaalsContact C-N 3.33Å; L84-N86 PolarHBondContact O-N 3.21Å; L84-S87 VanDerWaalsContact O-CB 3.28Å; L84-S87 WeakPolarHBondContact O-CB 3.46Å; L84-S87 PolarHBondContact O-N 3.37Å; L84-S87 VanDerWaalsContact O-N 3.09Å; L84-F88 HydrophobicContact CD1-CE2 3.89Å; L84-F88 HydrophobicContact CG-CE2 4.1Å; L84-F88 VanDerWaalsContact O-CD2 3.22Å; L84-F88 WeakPolarHBondContact O-CD2 3.37Å; L84-F436 HydrophobicContact CB-CD2 3.67Å; L84-F436 HydrophobicContact CB-CE2 3.77Å; L84-F436 HydrophobicContact CD1-CD2 4.13Å; L84-F436 HydrophobicContact CD1-CE2 3.97Å; L84-F436 HydrophobicContact CD1-CZ 4.2Å; L84-F436 HydrophobicContact CD2-CE2 4.4Å; L84-F436 HydrophobicContact CG-CD2 4.46Å; L84-F436 HydrophobicContact CG-CE2 4.26Å
85	L	86	Confident	84.2	Confident	69 Å²	69	53 Å²	53	36%	0.361	28%	0.276	S	S	.	.	H	α-helix	trans	-63.8	-37.8	-178.4	-171.6	63.4	0	0	0	111.9	L81 F82 S87 F88 L89	L81-L85 VanDerWaalsContact O-CB 3.26Å; L81-L85 WeakPolarHBondContact O-CB 3.38Å; L81-L85 PolarHBondContact O-N 3.3Å; F82-L85 HydrophobicContact CD1-CD2 4.5Å; L85-S87 PolarHBondContact O-N 2.9Å; L85-F88 PolarHBondContact O-N 3.31Å; L85-L89 HydrophobicContact CD1-CD1 4.22Å; L85-L89 HydrophobicContact CD1-CG 4.07Å; L85-L89 HydrophobicContact CD2-CD1 3.67Å; L85-L89 HydrophobicContact CD2-CG 4.43Å; L85-L89 HydrophobicContact CG-CD1 3.48Å; L85-L89 VanDerWaalsContact CG-CD1 3.48Å; L85-L89 HydrophobicContact CG-CG 3.77Å; L85-L89 WeakPolarHBondContact O-CB 3.49Å; L85-L89 WeakPolarHBondContact O-CG 3.49Å; L85-L89 PolarHBondContact O-N 3.09Å
86	N	82.1	Confident	84	Confident	4 Å²	4	56.7 Å²	56.7	2%	0.021	30%	0.299	C	S	.	.	H	α-helix	trans	-60.3	-31.7	175.3	-175.7	62.3	0	0	0	112.3	F82 L84 F88 L89 Y90 R98 G146	F82-N86 WeakPolarHBondContact O-CB 3.36Å; F82-N86 PolarHBondContact O-N 3.27Å; L84-N86 VanDerWaalsContact C-N 3.33Å; L84-N86 PolarHBondContact O-N 3.21Å; N86-F88 PolarHBondContact O-N 2.92Å; N86-L89 PolarHBondContact O-N 3.2Å; N86-Y90 PolarHBondContact O-N 3.07Å; N86-Y90 VanDerWaalsContact O-N 3.09Å; N86-R98 PolarHBondContact OD1-NH1 2.85Å; N86-G146 VanDerWaalsContact ND2-C 3.34Å; N86-G146 WeakPolarHBondContact ND2-CA 3.22Å
87	S	73.2	Confident	84	Confident	2 Å²	2	59.7 Å²	59.7	1%	0.014	32%	0.318	C	S	.	.	H	α-helix	trans	-65.9	-17.5	175.1	-55.6	0	0	0	0	113.1	T83 L84 L85 Y90	T83-S87 PolarHBondContact O-N 2.95Å; T83-S87 PolarHBondContact O-OG 3.13Å; T83-S87 VanDerWaalsContact O-OG 3.13Å; L84-S87 VanDerWaalsContact O-CB 3.28Å; L84-S87 WeakPolarHBondContact O-CB 3.46Å; L84-S87 PolarHBondContact O-N 3.37Å; L84-S87 VanDerWaalsContact O-N 3.09Å; L85-S87 PolarHBondContact O-N 2.9Å; S87-Y90 WeakPolarHBondContact O-CD1 3.31Å; S87-Y90 VanDerWaalsContact O-CE1 3.32Å; S87-Y90 WeakPolarHBondContact O-CE1 3.47Å
88	F	72.8	Confident	84	Confident	119 Å²	119	55.3 Å²	55.3	52%	0.522	29%	0.294	S	S	.	.	H	α-helix	trans	-103.5	-38.7	172.6	-59.3	-76.4	0	0	0	112.4	L84 L85 N86 Y90	L84-F88 HydrophobicContact CD1-CE2 3.89Å; L84-F88 HydrophobicContact CG-CE2 4.1Å; L84-F88 VanDerWaalsContact O-CD2 3.22Å; L84-F88 WeakPolarHBondContact O-CD2 3.37Å; L85-F88 PolarHBondContact O-N 3.31Å; N86-F88 PolarHBondContact O-N 2.92Å; F88-Y90 VanDerWaalsContact C-N 3.3Å; F88-Y90 PolarHBondContact O-N 2.89Å
89	L	69.4	Low	84.1	Confident	60 Å²	60	55.1 Å²	55.1	31%	0.314	29%	0.293	S	S	.	.	H	α-helix	trans	-74	-13.8	-176.7	-70.5	-177.8	0	0	0	114.4	L85 N86 Q91 C92 I93	L85-L89 HydrophobicContact CD1-CD1 4.22Å; L85-L89 HydrophobicContact CD1-CG 4.07Å; L85-L89 HydrophobicContact CD2-CD1 3.67Å; L85-L89 HydrophobicContact CD2-CG 4.43Å; L85-L89 HydrophobicContact CG-CD1 3.48Å; L85-L89 VanDerWaalsContact CG-CD1 3.48Å; L85-L89 HydrophobicContact CG-CG 3.77Å; L85-L89 WeakPolarHBondContact O-CB 3.49Å; L85-L89 WeakPolarHBondContact O-CG 3.49Å; L85-L89 PolarHBondContact O-N 3.09Å; N86-L89 PolarHBondContact O-N 3.2Å; L89-Q91 PolarHBondContact O-N 3.23Å; L89-C92 PolarHBondContact O-N 3.18Å; L89-I93 PolarHBondContact O-N 3.15Å
90	Y	71.6	Confident	84.2	Confident	33 Å²	33	56.8 Å²	56.8	13%	0.129	30%	0.302	C	S	.	.	T	Hydrogen-bonded Turn	trans	-57.1	-24.6	179.5	84.4	-82.1	0	0	0	113.3	N86 S87 F88 V429	N86-Y90 PolarHBondContact O-N 3.07Å; N86-Y90 VanDerWaalsContact O-N 3.09Å; S87-Y90 WeakPolarHBondContact O-CD1 3.31Å; S87-Y90 VanDerWaalsContact O-CE1 3.32Å; S87-Y90 WeakPolarHBondContact O-CE1 3.47Å; F88-Y90 VanDerWaalsContact C-N 3.3Å; F88-Y90 PolarHBondContact O-N 2.89Å; Y90-V429 HydrophobicContact CE1-CG2 4.26Å; Y90-V429 HydrophobicContact CE2-CG2 4.3Å; Y90-V429 WeakPolarHBondContact OH-CG2 3.47Å
91	Q	69.9	Low	84.4	Confident	96 Å²	96	55.9 Å²	55.9	45%	0.449	31%	0.305	S	S	.	.	T	Hydrogen-bonded Turn	trans	-78.1	-24	177.6	-57.8	-172.7	5.8	0	0	113.3	L89	L89-Q91 PolarHBondContact O-N 3.23Å
92	C	77.3	Confident	84.5	Confident	100 Å²	100	51.4 Å²	51.4	68%	0.676	28%	0.282	S	S	*	.	T	Hydrogen-bonded Turn	trans	-96.3	-30.6	-172.1	-62.8	0	0	0	0	112.9	L89	L89-C92 PolarHBondContact O-N 3.18Å
93	I	83.9	Confident	84.8	Confident	66 Å²	66	48.3 Å²	48.3	34%	0.338	27%	0.269	S	S	.	.	S	Bend	trans	-118.6	127.1	-171.1	-52.6	179.4	0	0	0	109.9	L89 E95 V97 R98	L89-I93 PolarHBondContact O-N 3.15Å; I93-E95 PolarHBondContact O-N 2.89Å; I93-V97 HydrophobicContact CG2-CB 4.14Å; I93-V97 HydrophobicContact CG2-CG1 4.07Å; I93-R98 HydrophobicContact CB-CG 3.9Å; I93-R98 HydrophobicContact CG2-CG 3.59Å; I93-R98 PolarHBondContact O-NE 3.15Å
94	P	86.3	Confident	85.2	Confident	80 Å²	80	52 Å²	52	52%	0.519	29%	0.288	S	S	.	.			trans	-53.8	138.9	175.4	-24.5	33.2	0	0	0	112.2	T96 V97 R98	P94-T96 VanDerWaalsContact C-N 3.29Å; P94-T96 PolarHBondContact O-N 3.17Å; P94-V97 HydrophobicContact CB-CB 4.46Å; P94-V97 HydrophobicContact CB-CG2 4.11Å; P94-V97 HydrophobicContact CG-CG2 4.32Å; P94-V97 PolarHBondContact O-N 3.45Å; P94-V97 VanDerWaalsContact O-N 3.1Å; P94-R98 PolarHBondContact O-N 2.72Å
95	E	84.3	Confident	85.6	Confident	47 Å²	47	49.6 Å²	49.6	22%	0.22	28%	0.278	C	S	.	.	H	α-helix	trans	-56.5	-41.2	-178.3	-168.7	-160.9	137.3	0	0	112.8	I93 V97 R98 I99 Q151	I93-E95 PolarHBondContact O-N 2.89Å; E95-V97 VanDerWaalsContact C-N 3.31Å; E95-V97 PolarHBondContact O-N 2.76Å; E95-R98 PolarHBondContact O-N 3.25Å; E95-I99 HydrophobicContact CG-CD1 3.88Å; E95-I99 PolarHBondContact O-N 3.07Å; E95-Q151 WeakPolarHBondContact OE1-CB 3.32Å; E95-Q151 WeakPolarHBondContact OE1-CG 3.4Å; E95-Q151 PolarHBondContact OE1-NE2 3.47Å
96	T	87.7	Confident	86.1	Confident	82 Å²	82	46.5 Å²	46.5	50%	0.503	26%	0.262	S	S	.	.	H	α-helix	trans	-61	-39.7	177.7	52	0	0	0	0	112.4	P94 L100 Y210	P94-T96 VanDerWaalsContact C-N 3.29Å; P94-T96 PolarHBondContact O-N 3.17Å; T96-L100 WeakPolarHBondContact O-CB 3.34Å; T96-L100 PolarHBondContact O-N 3.17Å; T96-Y210 WeakPolarHBondContact CA-OH 3.43Å; T96-Y210 HydrophobicContact CG2-CE1 4.38Å
97	V	90.8	Very high	86.9	Confident	86 Å²	86	47.6 Å²	47.6	52%	0.521	27%	0.267	S	S	.	.	H	α-helix	trans	-68.8	-41.4	176.7	177.8	0	0	0	0	110.3	I93 P94 E95 G101	I93-V97 HydrophobicContact CG2-CB 4.14Å; I93-V97 HydrophobicContact CG2-CG1 4.07Å; P94-V97 HydrophobicContact CB-CB 4.46Å; P94-V97 HydrophobicContact CB-CG2 4.11Å; P94-V97 HydrophobicContact CG-CG2 4.32Å; P94-V97 PolarHBondContact O-N 3.45Å; P94-V97 VanDerWaalsContact O-N 3.1Å; E95-V97 VanDerWaalsContact C-N 3.31Å; E95-V97 PolarHBondContact O-N 2.76Å; V97-G101 VanDerWaalsContact O-CA 3.25Å; V97-G101 WeakPolarHBondContact O-CA 3.26Å; V97-G101 PolarHBondContact O-N 3.4Å
98	R	91.9	Very high	88	Confident	13 Å²	13	53.3 Å²	53.3	5%	0.049	30%	0.297	C	S	.	.	H	α-helix	trans	-62.1	-49.6	177	-68.8	-170.8	-74.4	152.6	2.1	111.8	N86 I93 P94 E95 S102 V143 S147 E428	N86-R98 PolarHBondContact OD1-NH1 2.85Å; I93-R98 HydrophobicContact CB-CG 3.9Å; I93-R98 HydrophobicContact CG2-CG 3.59Å; I93-R98 PolarHBondContact O-NE 3.15Å; P94-R98 PolarHBondContact O-N 2.72Å; E95-R98 PolarHBondContact O-N 3.25Å; R98-S102 WeakPolarHBondContact O-CB 3.34Å; R98-S102 PolarHBondContact O-N 3.38Å; R98-S102 VanDerWaalsContact O-N 3.13Å; R98-S102 PolarHBondContact O-OG 2.96Å; R98-V143 HydrophobicContact CB-CG1 3.98Å; R98-V143 HydrophobicContact CG-CG1 4.28Å; R98-S147 WeakPolarHBondContact CB-OG 3.23Å; R98-S147 PolarHBondContact NH1-OG 3.44Å; R98-E428 IonicContact NH2-OE1 3.71Å
99	I	93.3	Very high	89.2	Confident	0 Å²	0	48.9 Å²	48.9	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-71.6	-56.6	-176.6	-66.5	173.2	0	0	0	111.1	E95 G101 S102 L103 L144 L148 Y210	E95-I99 HydrophobicContact CG-CD1 3.88Å; E95-I99 PolarHBondContact O-N 3.07Å; I99-G101 PolarHBondContact O-N 2.6Å; I99-S102 PolarHBondContact O-N 3.18Å; I99-L103 HydrophobicContact CG2-CD1 4.07Å; I99-L103 WeakPolarHBondContact O-CG 3.44Å; I99-L103 PolarHBondContact O-N 2.7Å; I99-L144 HydrophobicContact CB-CD1 4.34Å; I99-L144 HydrophobicContact CG2-CD1 3.82Å; I99-L148 HydrophobicContact CD1-CD2 3.83Å; I99-L148 HydrophobicContact CD1-CG 4.11Å; I99-L148 HydrophobicContact CG1-CD2 4.44Å; I99-L148 HydrophobicContact CG1-CG 4.32Å; I99-L148 HydrophobicContact CG2-CD2 4.3Å; I99-Y210 HydrophobicContact CB-CE1 4.21Å; I99-Y210 HydrophobicContact CB-CE2 4.12Å; I99-Y210 HydrophobicContact CD1-CE2 3.57Å; I99-Y210 HydrophobicContact CG1-CE2 4.43Å; I99-Y210 HydrophobicContact CG2-CD1 4.14Å; I99-Y210 HydrophobicContact CG2-CD2 3.76Å; I99-Y210 HydrophobicContact CG2-CE1 4.05Å; I99-Y210 HydrophobicContact CG2-CE2 3.68Å; I99-Y210 HydrophobicContact CG2-CG 4.01Å
100	L	95.1	Very high	90.4	Very high	46 Å²	46	46 Å²	46	24%	0.241	26%	0.264	C	S	.	.	H	α-helix	trans	-67.8	-39.8	-176.1	-174.1	61.2	0	0	0	111.8	T96 L103 L104 I207 L211	T96-L100 WeakPolarHBondContact O-CB 3.34Å; T96-L100 PolarHBondContact O-N 3.17Å; L100-L103 PolarHBondContact O-N 3.07Å; L100-L104 HydrophobicContact CD1-CD1 4.5Å; L100-L104 HydrophobicContact CD1-CG 4.49Å; L100-L104 HydrophobicContact CG-CD1 4.13Å; L100-L104 WeakPolarHBondContact O-CB 3.48Å; L100-L104 WeakPolarHBondContact O-CG 3.19Å; L100-L104 PolarHBondContact O-N 2.8Å; L100-I207 HydrophobicContact CD1-CB 4.36Å; L100-I207 HydrophobicContact CD1-CG1 4.13Å; L100-I207 HydrophobicContact CD1-CG2 3.56Å; L100-L211 HydrophobicContact CD2-CD2 4.11Å
101	G	95.2	Very high	91.5	Very high	34 Å²	34	46.6 Å²	46.6	35%	0.351	28%	0.276	S	S	.	.	H	α-helix	trans	-61.6	-42.6	175.5	0	0	0	0	0	112.1	V97 I99 L104 A105	V97-G101 VanDerWaalsContact O-CA 3.25Å; V97-G101 WeakPolarHBondContact O-CA 3.26Å; V97-G101 PolarHBondContact O-N 3.4Å; I99-G101 PolarHBondContact O-N 2.6Å; G101-L104 PolarHBondContact O-N 3.01Å; G101-A105 WeakPolarHBondContact O-CB 3.23Å; G101-A105 PolarHBondContact O-N 3.39Å
102	S	96.3	Very high	92.7	Very high	4 Å²	4	45.6 Å²	45.6	3%	0.028	27%	0.273	C	S	.	.	H	α-helix	trans	-66.7	-43	176.5	-59.6	0	0	0	0	112.1	R98 I99 L104 A105 I106 F140	R98-S102 WeakPolarHBondContact O-CB 3.34Å; R98-S102 PolarHBondContact O-N 3.38Å; R98-S102 VanDerWaalsContact O-N 3.13Å; R98-S102 PolarHBondContact O-OG 2.96Å; I99-S102 PolarHBondContact O-N 3.18Å; S102-L104 PolarHBondContact O-N 3Å; S102-A105 PolarHBondContact O-N 3.1Å; S102-I106 WeakPolarHBondContact O-CD1 3.41Å; S102-I106 WeakPolarHBondContact O-CG1 3.42Å; S102-I106 PolarHBondContact O-N 3.35Å; S102-F140 WeakPolarHBondContact CB-O 3.37Å; S102-F140 PolarHBondContact OG-O 3.13Å
103	L	96.8	Very high	93.5	Very high	2 Å²	2	41.1 Å²	41.1	1%	0.01	24%	0.242	C	C	.	.	H	α-helix	trans	-60.1	-45.2	175.7	-73.9	167.9	0	0	0	111.8	L21 I99 L100 I106 L107 L144 I203 I207	L21-L103 HydrophobicContact CD2-CD1 4.48Å; I99-L103 HydrophobicContact CG2-CD1 4.07Å; I99-L103 WeakPolarHBondContact O-CG 3.44Å; I99-L103 PolarHBondContact O-N 2.7Å; L100-L103 PolarHBondContact O-N 3.07Å; L103-I106 PolarHBondContact O-N 3.43Å; L103-L107 WeakPolarHBondContact O-CB 3.37Å; L103-L107 PolarHBondContact O-N 3.06Å; L103-L144 HydrophobicContact CD1-CD1 4.39Å; L103-L144 HydrophobicContact CD2-CD1 4.18Å; L103-L144 HydrophobicContact CD2-CD2 3.62Å; L103-L144 HydrophobicContact CG-CD1 3.85Å; L103-L144 HydrophobicContact CG-CD2 4.09Å; L103-I203 HydrophobicContact CB-CG2 4.24Å; L103-I203 HydrophobicContact CD2-CG2 4.13Å; L103-I203 WeakPolarHBondContact O-CG2 3.47Å; L103-I207 HydrophobicContact CB-CD1 4.11Å; L103-I207 HydrophobicContact CB-CG1 3.73Å; L103-I207 HydrophobicContact CD1-CG1 3.93Å; L103-I207 HydrophobicContact CG-CG1 4.38Å
104	L	97.3	Very high	93.9	Very high	80 Å²	80	38.3 Å²	38.3	42%	0.419	23%	0.229	S	C	.	.	H	α-helix	trans	-64.5	-42	177.1	-72.9	171	0	0	0	112	L100 G101 S102 L107 L108 I207	L100-L104 HydrophobicContact CD1-CD1 4.5Å; L100-L104 HydrophobicContact CD1-CG 4.49Å; L100-L104 HydrophobicContact CG-CD1 4.13Å; L100-L104 WeakPolarHBondContact O-CB 3.48Å; L100-L104 WeakPolarHBondContact O-CG 3.19Å; L100-L104 PolarHBondContact O-N 2.8Å; G101-L104 PolarHBondContact O-N 3.01Å; S102-L104 PolarHBondContact O-N 3Å; L104-L107 WeakPolarHBondContact O-CB 3.49Å; L104-L107 PolarHBondContact O-N 3.26Å; L104-L108 VanDerWaalsContact O-CG 3.32Å; L104-L108 WeakPolarHBondContact O-CG 3.41Å; L104-L108 PolarHBondContact O-N 2.84Å; L104-I207 HydrophobicContact CD2-CD1 3.93Å; L104-I207 HydrophobicContact CG-CD1 4.38Å
105	A	97.3	Very high	94.3	Very high	18 Å²	18	37.1 Å²	37.1	15%	0.149	23%	0.226	C	C	.	.	H	α-helix	trans	-63.5	-45	177.1	0	0	0	0	0	111.9	G101 S102 L107 L108 L109 F140	G101-A105 WeakPolarHBondContact O-CB 3.23Å; G101-A105 PolarHBondContact O-N 3.39Å; S102-A105 PolarHBondContact O-N 3.1Å; A105-L107 VanDerWaalsContact C-N 3.34Å; A105-L107 PolarHBondContact O-N 2.79Å; A105-L108 PolarHBondContact O-N 2.86Å; A105-L109 VanDerWaalsContact O-CG 3.3Å; A105-L109 WeakPolarHBondContact O-CG 3.37Å; A105-L109 PolarHBondContact O-N 3.38Å; A105-F140 HydrophobicContact CB-CB 4.49Å; A105-F140 HydrophobicContact CB-CD1 3.84Å; A105-F140 HydrophobicContact CB-CD2 3.59Å; A105-F140 HydrophobicContact CB-CE1 3.88Å; A105-F140 HydrophobicContact CB-CE2 3.65Å; A105-F140 HydrophobicContact CB-CG 3.71Å; A105-F140 HydrophobicContact CB-CZ 3.79Å
106	I	96.7	Very high	94.7	Very high	4 Å²	4	35.7 Å²	35.7	2%	0.021	22%	0.219	C	C	.	.	H	α-helix	trans	-62.6	-42.2	176.3	-63.7	163.8	0	0	0	110.3	P28 S102 L103 L108 L109 F110 F140 L144 I203	P28-I106 HydrophobicContact CB-CG2 4.2Å; P28-I106 HydrophobicContact CG-CG2 4.18Å; S102-I106 WeakPolarHBondContact O-CD1 3.41Å; S102-I106 WeakPolarHBondContact O-CG1 3.42Å; S102-I106 PolarHBondContact O-N 3.35Å; L103-I106 PolarHBondContact O-N 3.43Å; I106-L108 PolarHBondContact O-N 3.33Å; I106-L109 PolarHBondContact O-N 3.1Å; I106-F110 HydrophobicContact CG2-CD2 3.89Å; I106-F110 HydrophobicContact CG2-CE2 4.15Å; I106-F110 WeakPolarHBondContact O-CD2 3.34Å; I106-F110 PolarHBondContact O-N 3.04Å; I106-F140 HydrophobicContact CD1-CB 4.16Å; I106-F140 HydrophobicContact CG1-CB 3.81Å; I106-L144 HydrophobicContact CD1-CD2 3.9Å; I106-I203 HydrophobicContact CB-CD1 4.43Å; I106-I203 HydrophobicContact CG2-CD1 3.71Å
107	L	97.4	Very high	94.8	Very high	27 Å²	27	31.9 Å²	31.9	14%	0.141	20%	0.196	C	C	.	.	H	α-helix	trans	-57.9	-47.7	176	178.9	64.4	0	0	0	111.8	L103 L104 A105 L109 F110 A111 C200 I203 L204 I207	L103-L107 WeakPolarHBondContact O-CB 3.37Å; L103-L107 PolarHBondContact O-N 3.06Å; L104-L107 WeakPolarHBondContact O-CB 3.49Å; L104-L107 PolarHBondContact O-N 3.26Å; A105-L107 VanDerWaalsContact C-N 3.34Å; A105-L107 PolarHBondContact O-N 2.79Å; L107-L109 PolarHBondContact O-N 3.01Å; L107-F110 PolarHBondContact O-N 2.89Å; L107-A111 WeakPolarHBondContact O-CB 3.37Å; L107-A111 PolarHBondContact O-N 3.24Å; L107-C200 HydrophobicContact CD1-CB 3.65Å; L107-I203 HydrophobicContact CB-CD1 4.49Å; L107-I203 HydrophobicContact CB-CG2 3.92Å; L107-I203 HydrophobicContact CD1-CB 4.41Å; L107-I203 HydrophobicContact CD1-CG2 4.47Å; L107-L204 HydrophobicContact CD1-CG 4.33Å; L107-L204 HydrophobicContact CD2-CD2 3.7Å; L107-L204 HydrophobicContact CD2-CG 4.18Å; L107-I207 HydrophobicContact CD2-CD1 4.41Å
108	L	97.4	Very high	94.7	Very high	123 Å²	123	34 Å²	34	64%	0.644	20%	0.198	S	C	*	.	H	α-helix	trans	-63.7	-40.3	178.9	-70.2	171.7	0	0	0	112	L104 A105 I106 A111 L112	L104-L108 VanDerWaalsContact O-CG 3.32Å; L104-L108 WeakPolarHBondContact O-CG 3.41Å; L104-L108 PolarHBondContact O-N 2.84Å; A105-L108 PolarHBondContact O-N 2.86Å; I106-L108 PolarHBondContact O-N 3.33Å; L108-A111 PolarHBondContact O-N 2.81Å; L108-L112 WeakPolarHBondContact O-CB 3.45Å; L108-L112 PolarHBondContact O-N 3.33Å
109	L	96.6	Very high	94.7	Very high	26 Å²	26	37 Å²	37	14%	0.136	22%	0.218	C	C	.	.	H	α-helix	trans	-68.3	-36.8	177.9	-70.1	166.1	0	0	0	112.5	A105 I106 L107 L112 T113 F136 I137 F140	A105-L109 VanDerWaalsContact O-CG 3.3Å; A105-L109 WeakPolarHBondContact O-CG 3.37Å; A105-L109 PolarHBondContact O-N 3.38Å; I106-L109 PolarHBondContact O-N 3.1Å; L107-L109 PolarHBondContact O-N 3.01Å; L109-L112 PolarHBondContact O-N 3.5Å; L109-T113 WeakPolarHBondContact O-CB 3.38Å; L109-T113 PolarHBondContact O-N 3.05Å; L109-T113 PolarHBondContact O-OG1 3.49Å; L109-F136 HydrophobicContact CD1-CB 3.63Å; L109-F136 HydrophobicContact CD2-CB 4.38Å; L109-I137 HydrophobicContact CB-CD1 4.19Å; L109-I137 HydrophobicContact CB-CG1 3.77Å; L109-I137 HydrophobicContact CD1-CG1 3.86Å; L109-I137 HydrophobicContact CG-CG1 4.41Å; L109-F140 HydrophobicContact CD1-CD2 4.12Å; L109-F140 HydrophobicContact CD1-CE2 4.4Å
110	F	94.6	Very high	94.3	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-71.7	-38	173.4	-92.4	-100.3	0	0	0	112.4	P28 F32 I106 L107 L112 T113 A114 I137 F196 P199	P28-F110 HydrophobicContact CB-CD1 4.3Å; P28-F110 HydrophobicContact CB-CD2 3.9Å; P28-F110 HydrophobicContact CB-CE1 3.78Å; P28-F110 HydrophobicContact CB-CE2 3.32Å; P28-F110 HydrophobicContact CB-CG 4.37Å; P28-F110 HydrophobicContact CB-CZ 3.28Å; P28-F110 WeakPolarHBondContact O-CE1 3.48Å; P28-F110 WeakPolarHBondContact O-CZ 3.11Å; F32-F110 HydrophobicContact CB-CE1 4.48Å; F32-F110 HydrophobicContact CB-CZ 4.13Å; F32-F110 HydrophobicContact CD2-CZ 4.41Å; I106-F110 HydrophobicContact CG2-CD2 3.89Å; I106-F110 HydrophobicContact CG2-CE2 4.15Å; I106-F110 WeakPolarHBondContact O-CD2 3.34Å; I106-F110 PolarHBondContact O-N 3.04Å; L107-F110 PolarHBondContact O-N 2.89Å; F110-L112 VanDerWaalsContact C-N 3.33Å; F110-T113 PolarHBondContact O-N 3.03Å; F110-A114 WeakPolarHBondContact O-CB 3.46Å; F110-A114 PolarHBondContact O-N 3.41Å; F110-I137 HydrophobicContact CD2-CD1 3.99Å; F110-I137 HydrophobicContact CD2-CG1 4.35Å; F110-I137 HydrophobicContact CE2-CD1 3.58Å; F110-I137 HydrophobicContact CE2-CG1 4.04Å; F110-I137 HydrophobicContact CE2-CG2 3.99Å; F110-I137 HydrophobicContact CZ-CD1 4.34Å; F110-F196 HydrophobicContact CD1-CD1 4.15Å; F110-F196 HydrophobicContact CE1-CD1 4.1Å; F110-P199 HydrophobicContact CD1-CB 4.12Å; F110-P199 HydrophobicContact CD1-CG 4.35Å; F110-P199 HydrophobicContact CE1-CB 4.31Å; F110-P199 HydrophobicContact CE1-CG 4.28Å
111	A	95.3	Very high	93.9	Very high	45 Å²	45	44.4 Å²	44.4	37%	0.372	26%	0.257	S	S	.	.	H	α-helix	trans	-62.2	-41.5	172.1	0	0	0	0	0	111.5	L107 L108 A114 A115	L107-A111 WeakPolarHBondContact O-CB 3.37Å; L107-A111 PolarHBondContact O-N 3.24Å; L108-A111 PolarHBondContact O-N 2.81Å; A111-A114 PolarHBondContact O-N 3.46Å; A111-A115 WeakPolarHBondContact O-CB 3.37Å; A111-A115 PolarHBondContact O-N 3.31Å
112	L	95	Very high	93.6	Very high	75 Å²	75	46.2 Å²	46.2	39%	0.393	26%	0.264	S	S	.	.	H	α-helix	trans	-59.3	-48	171.2	175.7	65	0	0	0	110.9	L108 L109 F110 A114 A115 L116	L108-L112 WeakPolarHBondContact O-CB 3.45Å; L108-L112 PolarHBondContact O-N 3.33Å; L109-L112 PolarHBondContact O-N 3.5Å; F110-L112 VanDerWaalsContact C-N 3.33Å; L112-A114 VanDerWaalsContact C-N 3.31Å; L112-A114 PolarHBondContact O-N 3.07Å; L112-A115 WeakPolarHBondContact O-CB 3.36Å; L112-A115 PolarHBondContact O-N 2.99Å; L112-A115 VanDerWaalsContact O-N 3.13Å; L112-L116 HydrophobicContact CD1-CG 4.34Å; L112-L116 HydrophobicContact CG-CD1 4.22Å; L112-L116 HydrophobicContact CG-CG 4.46Å; L112-L116 VanDerWaalsContact O-CG 3.31Å; L112-L116 WeakPolarHBondContact O-CG 3.1Å; L112-L116 PolarHBondContact O-N 3.39Å
113	T	93.7	Very high	93.1	Very high	6 Å²	6	47.2 Å²	47.2	4%	0.037	27%	0.27	C	S	.	.	H	α-helix	trans	-59.5	-42.5	178.7	-55.2	0	0	0	0	111.4	F32 F39 L109 F110 L116 V117 F196	F32-T113 HydrophobicContact CE2-CG2 4.49Å; F39-T113 HydrophobicContact CZ-CG2 4.1Å; L109-T113 WeakPolarHBondContact O-CB 3.38Å; L109-T113 PolarHBondContact O-N 3.05Å; L109-T113 PolarHBondContact O-OG1 3.49Å; F110-T113 PolarHBondContact O-N 3.03Å; T113-L116 PolarHBondContact O-N 2.92Å; T113-V117 PolarHBondContact O-N 3.34Å; T113-F196 HydrophobicContact CG2-CD1 3.83Å; T113-F196 HydrophobicContact CG2-CD2 3.98Å; T113-F196 HydrophobicContact CG2-CE1 3.72Å; T113-F196 HydrophobicContact CG2-CE2 3.88Å; T113-F196 HydrophobicContact CG2-CG 3.98Å; T113-F196 HydrophobicContact CG2-CZ 3.76Å
114	A	93.8	Very high	92.7	Very high	7 Å²	7	48.5 Å²	48.5	6%	0.058	29%	0.285	C	S	.	.	H	α-helix	trans	-63.3	-41.3	174.6	0	0	0	0	0	112.4	F110 A111 L112 V117 L193 F196 I197	F110-A114 WeakPolarHBondContact O-CB 3.46Å; F110-A114 PolarHBondContact O-N 3.41Å; A111-A114 PolarHBondContact O-N 3.46Å; L112-A114 VanDerWaalsContact C-N 3.31Å; L112-A114 PolarHBondContact O-N 3.07Å; A114-V117 WeakPolarHBondContact O-CB 3.29Å; A114-V117 PolarHBondContact O-N 3.07Å; A114-L193 WeakPolarHBondContact O-CD2 3.42Å; A114-F196 HydrophobicContact CB-CB 3.8Å; A114-I197 HydrophobicContact CB-CD1 3.95Å; A114-I197 HydrophobicContact CB-CG1 4.49Å
115	A	93.7	Very high	92.4	Very high	54 Å²	54	47.7 Å²	47.7	45%	0.446	28%	0.284	S	S	.	.	H	α-helix	trans	-63.4	-42.3	175.3	0	0	0	0	0	111.5	A111 L112 V117 K118 V119	A111-A115 WeakPolarHBondContact O-CB 3.37Å; A111-A115 PolarHBondContact O-N 3.31Å; L112-A115 WeakPolarHBondContact O-CB 3.36Å; L112-A115 PolarHBondContact O-N 2.99Å; L112-A115 VanDerWaalsContact O-N 3.13Å; A115-V117 PolarHBondContact O-N 3.37Å; A115-K118 PolarHBondContact O-N 3.49Å; A115-V119 PolarHBondContact O-N 3.06Å
116	L	92.5	Very high	92.1	Very high	17 Å²	17	47 Å²	47	9%	0.089	28%	0.278	C	S	.	.	H	α-helix	trans	-60.1	-25.9	176.5	-68.9	173.5	0	0	0	112.5	R42 L112 T113 K118 V119 M121 I129	R42-L116 PolarHBondContact NH1-O 3.3Å; R42-L116 PolarHBondContact NH2-O 3.41Å; L112-L116 HydrophobicContact CD1-CG 4.34Å; L112-L116 HydrophobicContact CG-CD1 4.22Å; L112-L116 HydrophobicContact CG-CG 4.46Å; L112-L116 VanDerWaalsContact O-CG 3.31Å; L112-L116 WeakPolarHBondContact O-CG 3.1Å; L112-L116 PolarHBondContact O-N 3.39Å; T113-L116 PolarHBondContact O-N 2.92Å; L116-K118 PolarHBondContact O-N 2.95Å; L116-V119 PolarHBondContact O-N 2.91Å; L116-M121 HydrophobicContact CD2-SD 3.9Å; L116-I129 HydrophobicContact CD1-CG2 3.6Å
117	V	90.7	Very high	91.9	Very high	3 Å²	3	48 Å²	48	2%	0.018	28%	0.282	C	S	.	.	H	α-helix	trans	-59.7	-33.5	173.9	176.2	0	0	0	0	112.2	Y38 R42 T113 A114 A115 Q189 A192 L193 F196	Y38-V117 HydrophobicContact CE1-CG2 4.05Å; Y38-V117 HydrophobicContact CE2-CG1 4.28Å; Y38-V117 WeakPolarHBondContact OH-CA 3.49Å; Y38-V117 WeakPolarHBondContact OH-CG1 3.41Å; R42-V117 PolarHBondContact NH1-O 3.37Å; T113-V117 PolarHBondContact O-N 3.34Å; A114-V117 WeakPolarHBondContact O-CB 3.29Å; A114-V117 PolarHBondContact O-N 3.07Å; A115-V117 PolarHBondContact O-N 3.37Å; V117-Q189 HydrophobicContact CG1-CB 4.31Å; V117-A192 HydrophobicContact CG1-CB 4.49Å; V117-A192 HydrophobicContact CG2-CB 4.41Å; V117-L193 HydrophobicContact CB-CD2 3.73Å; V117-L193 HydrophobicContact CB-CG 4.23Å; V117-L193 HydrophobicContact CG1-CD1 4.4Å; V117-L193 HydrophobicContact CG1-CD2 3.78Å; V117-L193 HydrophobicContact CG1-CG 3.71Å; V117-L193 HydrophobicContact CG2-CD2 4.36Å; V117-F196 HydrophobicContact CG2-CD2 3.62Å; V117-F196 HydrophobicContact CG2-CE2 3.64Å
118	K	89.1	Confident	91.7	Very high	130 Å²	130	50.3 Å²	50.3	57%	0.565	30%	0.3	S	S	*	.	H	α-helix	trans	-94.8	-17.8	-178.7	-70.2	-58.7	-159.1	-167.8	0	114.7	A115 L116 L193	A115-K118 PolarHBondContact O-N 3.49Å; L116-K118 PolarHBondContact O-N 2.95Å; K118-L193 HydrophobicContact CD-CD1 4.11Å; K118-L193 HydrophobicContact CG-CD1 4.46Å; K118-L193 HydrophobicContact CG-CD2 4.36Å
119	V	90.5	Very high	91.5	Very high	75 Å²	75	47.7 Å²	47.7	46%	0.455	29%	0.286	S	S	.	.	S	Bend	trans	-81.9	122.3	-179.1	174.6	0	0	0	0	109.7	R42 A115 L116 M121	R42-V119 PolarHBondContact NH2-O 2.76Å; A115-V119 PolarHBondContact O-N 3.06Å; L116-V119 PolarHBondContact O-N 2.91Å; V119-M121 PolarHBondContact O-N 3.46Å
120	D	86.1	Confident	91.4	Very high	154 Å²	154	46.6 Å²	46.6	82%	0.824	28%	0.28	S	S	*	.			trans	-72	123.2	171.5	-70.1	-39.3	0	0	0	110.4
121	M	86.3	Confident	91.4	Very high	49 Å²	49	47.1 Å²	47.1	24%	0.241	28%	0.283	C	S	.	.			trans	-154.1	154	-176	59.8	-177.4	-49.3	0	0	111.1	L116 V119 P125 F126 I129	L116-M121 HydrophobicContact CD2-SD 3.9Å; V119-M121 PolarHBondContact O-N 3.46Å; M121-P125 HydrophobicContact CE-CB 3.94Å; M121-F126 HydrophobicContact CE-CB 3.83Å; M121-F126 HydrophobicContact CE-CD2 4.5Å; M121-F126 VanDerWaalsContact CE-N 3.29Å; M121-F126 HydrophobicContact CG-CB 3.94Å; M121-F126 HydrophobicContact CG-CD2 4.21Å; M121-F126 HydrophobicContact CG-CG 4.45Å; M121-F126 HydrophobicContact SD-CB 3.78Å; M121-F126 HydrophobicContact SD-CD2 3.55Å; M121-F126 VanDerWaalsContact SD-CD2 3.55Å; M121-F126 HydrophobicContact SD-CG 4.13Å; M121-I129 HydrophobicContact CE-CD1 3.98Å
122	S	87.9	Confident	91.4	Very high	71 Å²	71	47 Å²	47	50%	0.497	28%	0.282	S	S	.	.			trans	-70.1	155.7	179.8	56.3	0	0	0	0	112.4	G124 P125 F126	S122-G124 PolarHBondContact O-N 2.99Å; S122-P125 WeakPolarHBondContact O-CD 3.35Å; S122-P125 WeakPolarHBondContact OG-CD 3.35Å; S122-P125 WeakPolarHBondContact OG-CG 3.49Å; S122-F126 WeakPolarHBondContact O-CB 3.36Å; S122-F126 PolarHBondContact O-N 3.45Å
123	P	86.8	Confident	91.4	Very high	25 Å²	25	43.7 Å²	43.7	16%	0.162	27%	0.265	C	S	.	.	H	α-helix	trans	-57.7	-42.1	-174.1	-28.1	35.1	0	0	0	114.9	L43 A46 F65 F126 F127	L43-P123 HydrophobicContact CD2-CB 4.16Å; L43-P123 WeakPolarHBondContact CD2-O 3.42Å; A46-P123 HydrophobicContact CB-CG 3.43Å; A46-P123 VanDerWaalsContact CB-CG 3.43Å; F65-P123 HydrophobicContact CE2-CB 4.23Å; F65-P123 HydrophobicContact CZ-CB 4.11Å; P123-F126 PolarHBondContact O-N 3.3Å; P123-F127 VanDerWaalsContact O-CB 3.3Å; P123-F127 WeakPolarHBondContact O-CB 3.33Å; P123-F127 PolarHBondContact O-N 3.08Å
124	G	87.9	Confident	91.5	Very high	30 Å²	30	43.4 Å²	43.4	31%	0.309	26%	0.264	S	S	.	.	H	α-helix	trans	-61.6	-57.7	-176.3	0	0	0	0	0	112.8	S122 F126 F127 S128	S122-G124 PolarHBondContact O-N 2.99Å; G124-F126 VanDerWaalsContact C-N 3.3Å; G124-F126 PolarHBondContact O-N 3.22Å; G124-F127 WeakPolarHBondContact O-CB 3.39Å; G124-F127 PolarHBondContact O-N 3.44Å; G124-S128 PolarHBondContact O-N 2.82Å; G124-S128 PolarHBondContact O-OG 3.36Å
125	P	90.8	Very high	91.6	Very high	62 Å²	62	44.9 Å²	44.9	40%	0.403	27%	0.273	S	S	.	.	H	α-helix	trans	-58.3	-38.6	174.4	-26.9	36	0	0	0	113.5	M121 S122 S128 I129	M121-P125 HydrophobicContact CE-CB 3.94Å; S122-P125 WeakPolarHBondContact O-CD 3.35Å; S122-P125 WeakPolarHBondContact OG-CD 3.35Å; S122-P125 WeakPolarHBondContact OG-CG 3.49Å; P125-S128 PolarHBondContact O-N 3.29Å; P125-I129 WeakPolarHBondContact O-CB 3.24Å; P125-I129 VanDerWaalsContact O-CG1 3.27Å; P125-I129 WeakPolarHBondContact O-CG1 3.25Å; P125-I129 PolarHBondContact O-N 3.25Å
126	F	91.9	Very high	91.7	Very high	4 Å²	4	47.7 Å²	47.7	2%	0.018	28%	0.275	C	S	.	.	H	α-helix	trans	-61.8	-46.2	177.1	178	-109.4	0	0	0	111.5	Y38 F39 R42 L43 M121 S122 P123 G124 T130	Y38-F126 HydrophobicContact CE1-CZ 4.36Å; F39-F126 AromaticContact CD1-CE1 3.78Å; F39-F126 HydrophobicContact CD1-CE1 3.78Å; F39-F126 AromaticContact CD1-CZ 3.5Å; F39-F126 HydrophobicContact CD1-CZ 3.5Å; F39-F126 HydrophobicContact CE1-CE1 4.47Å; F39-F126 AromaticContact CE1-CZ 3.8Å; F39-F126 HydrophobicContact CE1-CZ 3.8Å; R42-F126 HydrophobicContact CB-CE1 4.21Å; R42-F126 VanDerWaalsContact CD-CZ 3.48Å; R42-F126 HydrophobicContact CG-CD1 4.22Å; R42-F126 HydrophobicContact CG-CE1 3.87Å; R42-F126 HydrophobicContact CG-CZ 4.21Å; L43-F126 HydrophobicContact CD2-CD1 3.8Å; L43-F126 HydrophobicContact CD2-CE1 4.48Å; L43-F126 HydrophobicContact CG-CD1 4.22Å; L43-F126 HydrophobicContact CG-CE1 4.43Å; M121-F126 HydrophobicContact CE-CB 3.83Å; M121-F126 HydrophobicContact CE-CD2 4.5Å; M121-F126 VanDerWaalsContact CE-N 3.29Å; M121-F126 HydrophobicContact CG-CB 3.94Å; M121-F126 HydrophobicContact CG-CD2 4.21Å; M121-F126 HydrophobicContact CG-CG 4.45Å; M121-F126 HydrophobicContact SD-CB 3.78Å; M121-F126 HydrophobicContact SD-CD2 3.55Å; M121-F126 VanDerWaalsContact SD-CD2 3.55Å; M121-F126 HydrophobicContact SD-CG 4.13Å; S122-F126 WeakPolarHBondContact O-CB 3.36Å; S122-F126 PolarHBondContact O-N 3.45Å; P123-F126 PolarHBondContact O-N 3.3Å; G124-F126 VanDerWaalsContact C-N 3.3Å; G124-F126 PolarHBondContact O-N 3.22Å; F126-T130 VanDerWaalsContact O-CB 3.25Å; F126-T130 WeakPolarHBondContact O-CB 3.29Å; F126-T130 PolarHBondContact O-N 3.49Å; F126-T130 PolarHBondContact O-OG1 3.43Å
127	F	91.7	Very high	91.8	Very high	26 Å²	26	47 Å²	47	11%	0.114	27%	0.272	C	S	.	.	H	α-helix	trans	-58.1	-54	175	179	-96.8	0	0	0	111	L43 F65 F67 W70 P123 G124 I129 T130 M131	L43-F127 HydrophobicContact CD1-CD2 4Å; L43-F127 HydrophobicContact CD2-CB 3.9Å; F65-F127 HydrophobicContact CB-CD2 3.86Å; F65-F127 HydrophobicContact CB-CE2 3.68Å; F65-F127 HydrophobicContact CB-CZ 4.29Å; F65-F127 HydrophobicContact CD1-CB 4.26Å; F65-F127 HydrophobicContact CD1-CD1 4.07Å; F65-F127 AromaticContact CD1-CD2 3.91Å; F65-F127 HydrophobicContact CD1-CD2 3.91Å; F65-F127 HydrophobicContact CD1-CE1 4.4Å; F65-F127 HydrophobicContact CD1-CE2 4.25Å; F65-F127 AromaticContact CD1-CG 3.81Å; F65-F127 HydrophobicContact CD1-CG 3.81Å; F65-F127 HydrophobicContact CD1-CZ 4.49Å; F65-F127 HydrophobicContact CE1-CB 4.37Å; F65-F127 HydrophobicContact CE1-CG 4.35Å; F65-F127 HydrophobicContact CG-CD2 4.03Å; F65-F127 HydrophobicContact CG-CE2 4.3Å; F65-F127 HydrophobicContact CG-CG 4.37Å; F67-F127 HydrophobicContact CD2-CD2 4.08Å; F67-F127 HydrophobicContact CD2-CE2 4.03Å; W70-F127 HydrophobicContact CB-CZ 4.14Å; W70-F127 AromaticContact CD1-CZ 3.78Å; W70-F127 AromaticContact CG-CZ 3.95Å; W70-F127 HydrophobicContact CG-CZ 3.95Å; P123-F127 VanDerWaalsContact O-CB 3.3Å; P123-F127 WeakPolarHBondContact O-CB 3.33Å; P123-F127 PolarHBondContact O-N 3.08Å; G124-F127 WeakPolarHBondContact O-CB 3.39Å; G124-F127 PolarHBondContact O-N 3.44Å; F127-I129 PolarHBondContact O-N 2.93Å; F127-T130 PolarHBondContact O-N 3.34Å; F127-M131 HydrophobicContact CD1-CG 4.14Å; F127-M131 HydrophobicContact CD2-CE 3.81Å; F127-M131 HydrophobicContact CD2-CG 4.28Å; F127-M131 HydrophobicContact CE1-CG 3.79Å; F127-M131 HydrophobicContact CE2-CE 3.34Å; F127-M131 HydrophobicContact CE2-CG 3.94Å; F127-M131 HydrophobicContact CE2-SD 4.3Å; F127-M131 HydrophobicContact CG-CG 4.38Å; F127-M131 HydrophobicContact CZ-CE 3.92Å; F127-M131 HydrophobicContact CZ-CG 3.68Å; F127-M131 HydrophobicContact CZ-SD 4.31Å; F127-M131 WeakPolarHBondContact O-CB 3.29Å; F127-M131 VanDerWaalsContact O-CG 3.3Å; F127-M131 WeakPolarHBondContact O-CG 3.24Å; F127-M131 PolarHBondContact O-N 2.94Å
128	S	92.4	Very high	92	Very high	74 Å²	74	47.1 Å²	47.1	52%	0.517	27%	0.272	S	S	.	.	H	α-helix	trans	-60.6	-44.1	-177	-62.3	0	0	0	0	113	G124 P125 M131 A132	G124-S128 PolarHBondContact O-N 2.82Å; G124-S128 PolarHBondContact O-OG 3.36Å; P125-S128 PolarHBondContact O-N 3.29Å; S128-M131 PolarHBondContact O-N 2.86Å; S128-A132 WeakPolarHBondContact O-CB 3.44Å; S128-A132 PolarHBondContact O-N 3Å
129	I	94.3	Very high	92.3	Very high	68 Å²	68	41.3 Å²	41.3	35%	0.349	25%	0.248	S	C	.	.	H	α-helix	trans	-67.4	-39.8	178.3	-65.6	174.4	0	0	0	110.8	L116 M121 P125 F127 A132 S133	L116-I129 HydrophobicContact CD1-CG2 3.6Å; M121-I129 HydrophobicContact CE-CD1 3.98Å; P125-I129 WeakPolarHBondContact O-CB 3.24Å; P125-I129 VanDerWaalsContact O-CG1 3.27Å; P125-I129 WeakPolarHBondContact O-CG1 3.25Å; P125-I129 PolarHBondContact O-N 3.25Å; F127-I129 PolarHBondContact O-N 2.93Å; I129-A132 PolarHBondContact O-N 3.38Å; I129-S133 WeakPolarHBondContact O-CB 3.3Å; I129-S133 PolarHBondContact O-N 2.99Å; I129-S133 PolarHBondContact O-OG 2.98Å
130	T	94.1	Very high	92.5	Very high	4 Å²	4	41.1 Å²	41.1	3%	0.025	24%	0.241	C	C	.	.	H	α-helix	trans	-63.3	-46.2	176.5	-58.9	0	0	0	0	110.7	F32 F39 F67 F126 F127 S133 V134	F32-T130 HydrophobicContact CZ-CG2 3.96Å; F39-T130 HydrophobicContact CD1-CG2 3.9Å; F39-T130 HydrophobicContact CE1-CG2 3.59Å; F39-T130 HydrophobicContact CZ-CG2 4.13Å; F67-T130 HydrophobicContact CE2-CG2 4.35Å; F126-T130 VanDerWaalsContact O-CB 3.25Å; F126-T130 WeakPolarHBondContact O-CB 3.29Å; F126-T130 PolarHBondContact O-N 3.49Å; F126-T130 PolarHBondContact O-OG1 3.43Å; F127-T130 PolarHBondContact O-N 3.34Å; T130-S133 WeakPolarHBondContact O-CB 3.32Å; T130-S133 PolarHBondContact O-N 3.18Å; T130-V134 WeakPolarHBondContact O-CG2 3.41Å; T130-V134 PolarHBondContact O-N 3.39Å
131	M	94.4	Very high	92.9	Very high	10 Å²	10	34.1 Å²	34.1	5%	0.049	20%	0.204	C	C	.	.	H	α-helix	trans	-63.5	-42.5	178.3	-71.6	-49.3	146.5	0	0	112.6	F67 W70 V71 L74 F127 S128 S133 V134 C135	F67-M131 HydrophobicContact CD2-CE 3.25Å; F67-M131 HydrophobicContact CE2-CE 3.2Å; F67-M131 HydrophobicContact CG-CE 4.09Å; F67-M131 HydrophobicContact CZ-CE 3.99Å; W70-M131 HydrophobicContact CB-CE 4.26Å; W70-M131 HydrophobicContact CB-SD 3.85Å; V71-M131 HydrophobicContact CG2-CE 3.63Å; V71-M131 HydrophobicContact CG2-SD 4.08Å; L74-M131 HydrophobicContact CD1-CB 3.55Å; L74-M131 HydrophobicContact CD1-CG 3.95Å; L74-M131 HydrophobicContact CD1-SD 3.77Å; F127-M131 HydrophobicContact CD1-CG 4.14Å; F127-M131 HydrophobicContact CD2-CE 3.81Å; F127-M131 HydrophobicContact CD2-CG 4.28Å; F127-M131 HydrophobicContact CE1-CG 3.79Å; F127-M131 HydrophobicContact CE2-CE 3.34Å; F127-M131 HydrophobicContact CE2-CG 3.94Å; F127-M131 HydrophobicContact CE2-SD 4.3Å; F127-M131 HydrophobicContact CG-CG 4.38Å; F127-M131 HydrophobicContact CZ-CE 3.92Å; F127-M131 HydrophobicContact CZ-CG 3.68Å; F127-M131 HydrophobicContact CZ-SD 4.31Å; F127-M131 WeakPolarHBondContact O-CB 3.29Å; F127-M131 VanDerWaalsContact O-CG 3.3Å; F127-M131 WeakPolarHBondContact O-CG 3.24Å; F127-M131 PolarHBondContact O-N 2.94Å; S128-M131 PolarHBondContact O-N 2.86Å; M131-S133 VanDerWaalsContact C-N 3.33Å; M131-S133 PolarHBondContact O-N 3.09Å; M131-V134 PolarHBondContact O-N 3.08Å; M131-C135 PolarHBondContact O-N 3.09Å; M131-C135 VanDerWaalsContact O-N 3.07Å
132	A	95.6	Very high	93.3	Very high	44 Å²	44	31.8 Å²	31.8	36%	0.364	19%	0.193	S	C	.	.	H	α-helix	trans	-60.1	-44.9	172.5	0	0	0	0	0	111.2	S128 I129 V134 C135 F136	S128-A132 WeakPolarHBondContact O-CB 3.44Å; S128-A132 PolarHBondContact O-N 3Å; I129-A132 PolarHBondContact O-N 3.38Å; A132-V134 PolarHBondContact O-N 2.86Å; A132-C135 WeakPolarHBondContact O-CB 3.35Å; A132-C135 PolarHBondContact O-N 2.93Å; A132-F136 WeakPolarHBondContact O-CD2 3.41Å; A132-F136 PolarHBondContact O-N 3.29Å
133	S	95.1	Very high	93.5	Very high	5 Å²	5	29.5 Å²	29.5	4%	0.035	18%	0.175	C	C	.	.	H	α-helix	trans	-61.2	-43.2	177.9	-57.7	0	0	0	0	111.8	I129 T130 M131 C135 F136 I137	I129-S133 WeakPolarHBondContact O-CB 3.3Å; I129-S133 PolarHBondContact O-N 2.99Å; I129-S133 PolarHBondContact O-OG 2.98Å; T130-S133 WeakPolarHBondContact O-CB 3.32Å; T130-S133 PolarHBondContact O-N 3.18Å; M131-S133 VanDerWaalsContact C-N 3.33Å; M131-S133 PolarHBondContact O-N 3.09Å; S133-C135 VanDerWaalsContact C-N 3.33Å; S133-C135 PolarHBondContact O-N 3.37Å; S133-F136 PolarHBondContact O-N 2.91Å; S133-I137 WeakPolarHBondContact O-CB 3.5Å; S133-I137 WeakPolarHBondContact O-CD1 3.38Å; S133-I137 WeakPolarHBondContact O-CG1 3.34Å; S133-I137 PolarHBondContact O-N 3.35Å
134	V	95.3	Very high	93.9	Very high	0 Å²	0	28.3 Å²	28.3	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-58.2	-45.2	175	170	0	0	0	0	111.3	W29 F32 L74 T130 M131 A132 I137 N138	W29-V134 HydrophobicContact CH2-CG1 4.32Å; W29-V134 HydrophobicContact CZ3-CG1 4.17Å; F32-V134 HydrophobicContact CD1-CG2 4.5Å; F32-V134 HydrophobicContact CE1-CG2 3.56Å; F32-V134 HydrophobicContact CE2-CG2 3.94Å; F32-V134 HydrophobicContact CZ-CG2 3.22Å; L74-V134 HydrophobicContact CB-CG1 4.18Å; T130-V134 WeakPolarHBondContact O-CG2 3.41Å; T130-V134 PolarHBondContact O-N 3.39Å; M131-V134 PolarHBondContact O-N 3.08Å; A132-V134 PolarHBondContact O-N 2.86Å; V134-I137 PolarHBondContact O-N 2.66Å; V134-N138 PolarHBondContact O-N 3.01Å; V134-N138 PolarHBondContact O-ND2 3.2Å
135	C	96	Very high	94.1	Very high	37 Å²	37	27.6 Å²	27.6	25%	0.25	16%	0.156	C	C	.	.	H	α-helix	trans	-59.9	-48.9	178.3	-179.2	0	0	0	0	111.7	P78 M131 A132 S133 N138 S139	P78-C135 HydrophobicContact CG-CB 4.29Å; P78-C135 WeakPolarHBondContact CG-SG 3.42Å; M131-C135 PolarHBondContact O-N 3.09Å; M131-C135 VanDerWaalsContact O-N 3.07Å; A132-C135 WeakPolarHBondContact O-CB 3.35Å; A132-C135 PolarHBondContact O-N 2.93Å; S133-C135 VanDerWaalsContact C-N 3.33Å; S133-C135 PolarHBondContact O-N 3.37Å; C135-N138 PolarHBondContact O-N 2.87Å; C135-S139 WeakPolarHBondContact O-CB 3.3Å; C135-S139 PolarHBondContact O-N 3.34Å; C135-S139 PolarHBondContact O-OG 3.08Å
136	F	96	Very high	94	Very high	114 Å²	114	24.7 Å²	24.7	50%	0.5	14%	0.138	S	C	.	.	H	α-helix	trans	-66.8	-42.6	178	-72.7	-65.3	0	0	0	112.9	L109 A132 S133 N138 S139 F140	L109-F136 HydrophobicContact CD1-CB 3.63Å; L109-F136 HydrophobicContact CD2-CB 4.38Å; A132-F136 WeakPolarHBondContact O-CD2 3.41Å; A132-F136 PolarHBondContact O-N 3.29Å; S133-F136 PolarHBondContact O-N 2.91Å; F136-N138 VanDerWaalsContact C-N 3.3Å; F136-N138 PolarHBondContact O-N 3.28Å; F136-S139 WeakPolarHBondContact O-CB 3.2Å; F136-S139 PolarHBondContact O-N 2.68Å; F136-S139 VanDerWaalsContact O-N 3.16Å; F136-F140 HydrophobicContact CB-CD2 4.47Å; F136-F140 HydrophobicContact CB-CE2 4.36Å; F136-F140 HydrophobicContact CD1-CE2 4.44Å; F136-F140 WeakPolarHBondContact O-CD2 3.35Å; F136-F140 PolarHBondContact O-N 3.48Å
137	I	95.4	Very high	94	Very high	2 Å²	2	24.6 Å²	24.6	1%	0.01	14%	0.138	C	C	.	.	H	α-helix	trans	-55.5	-47.9	176.5	-74	162.2	0	0	0	110.1	L109 F110 S133 V134 S139 S141	L109-I137 HydrophobicContact CB-CD1 4.19Å; L109-I137 HydrophobicContact CB-CG1 3.77Å; L109-I137 HydrophobicContact CD1-CG1 3.86Å; L109-I137 HydrophobicContact CG-CG1 4.41Å; F110-I137 HydrophobicContact CD2-CD1 3.99Å; F110-I137 HydrophobicContact CD2-CG1 4.35Å; F110-I137 HydrophobicContact CE2-CD1 3.58Å; F110-I137 HydrophobicContact CE2-CG1 4.04Å; F110-I137 HydrophobicContact CE2-CG2 3.99Å; F110-I137 HydrophobicContact CZ-CD1 4.34Å; S133-I137 WeakPolarHBondContact O-CB 3.5Å; S133-I137 WeakPolarHBondContact O-CD1 3.38Å; S133-I137 WeakPolarHBondContact O-CG1 3.34Å; S133-I137 PolarHBondContact O-N 3.35Å; V134-I137 PolarHBondContact O-N 2.66Å; I137-S139 VanDerWaalsContact C-N 3.35Å; I137-S141 VanDerWaalsContact O-CB 3.24Å; I137-S141 WeakPolarHBondContact O-CB 3.28Å; I137-S141 PolarHBondContact O-N 3.38Å; I137-S141 PolarHBondContact O-OG 3.31Å
138	N	94.8	Very high	94	Very high	6 Å²	6	23.3 Å²	23.3	3%	0.032	13%	0.132	C	C	.	.	H	α-helix	trans	-70.4	-32	-179.3	-77.8	-81.7	0	0	0	112.4	S75 V134 C135 F136 S141 A142	S75-N138 VanDerWaalsContact CA-CG 3.5Å; S75-N138 WeakPolarHBondContact CA-ND2 3.49Å; S75-N138 WeakPolarHBondContact O-CB 3.39Å; V134-N138 PolarHBondContact O-N 3.01Å; V134-N138 PolarHBondContact O-ND2 3.2Å; C135-N138 PolarHBondContact O-N 2.87Å; F136-N138 VanDerWaalsContact C-N 3.3Å; F136-N138 PolarHBondContact O-N 3.28Å; N138-S141 PolarHBondContact O-N 2.93Å; N138-A142 WeakPolarHBondContact O-CB 3.42Å; N138-A142 PolarHBondContact O-N 2.92Å
139	S	95	Very high	93.9	Very high	7 Å²	7	20.1 Å²	20.1	5%	0.049	11%	0.109	C	C	.	.	H	α-helix	trans	-64.2	-48.6	174.5	-56.4	0	0	0	0	111.8	P78 F82 C135 F136 I137 A142 V143	P78-S139 VanDerWaalsContact CB-OG 3.32Å; P78-S139 WeakPolarHBondContact CB-OG 3.13Å; F82-S139 WeakPolarHBondContact CD2-OG 3.47Å; F82-S139 VanDerWaalsContact CE2-OG 3.31Å; F82-S139 WeakPolarHBondContact CE2-OG 3.41Å; C135-S139 WeakPolarHBondContact O-CB 3.3Å; C135-S139 PolarHBondContact O-N 3.34Å; C135-S139 PolarHBondContact O-OG 3.08Å; F136-S139 WeakPolarHBondContact O-CB 3.2Å; F136-S139 PolarHBondContact O-N 2.68Å; F136-S139 VanDerWaalsContact O-N 3.16Å; I137-S139 VanDerWaalsContact C-N 3.35Å; S139-A142 WeakPolarHBondContact O-CB 3.32Å; S139-A142 PolarHBondContact O-N 3.1Å; S139-V143 PolarHBondContact O-N 3.11Å
140	F	95.2	Very high	93.4	Very high	71 Å²	71	17 Å²	17	31%	0.311	9%	0.093	S	C	.	.	H	α-helix	trans	-70.4	-33.8	176.3	-70.4	-65.2	0	0	0	112.1	S102 A105 I106 L109 F136 A142 V143 L144	S102-F140 WeakPolarHBondContact CB-O 3.37Å; S102-F140 PolarHBondContact OG-O 3.13Å; A105-F140 HydrophobicContact CB-CB 4.49Å; A105-F140 HydrophobicContact CB-CD1 3.84Å; A105-F140 HydrophobicContact CB-CD2 3.59Å; A105-F140 HydrophobicContact CB-CE1 3.88Å; A105-F140 HydrophobicContact CB-CE2 3.65Å; A105-F140 HydrophobicContact CB-CG 3.71Å; A105-F140 HydrophobicContact CB-CZ 3.79Å; I106-F140 HydrophobicContact CD1-CB 4.16Å; I106-F140 HydrophobicContact CG1-CB 3.81Å; L109-F140 HydrophobicContact CD1-CD2 4.12Å; L109-F140 HydrophobicContact CD1-CE2 4.4Å; F136-F140 HydrophobicContact CB-CD2 4.47Å; F136-F140 HydrophobicContact CB-CE2 4.36Å; F136-F140 HydrophobicContact CD1-CE2 4.44Å; F136-F140 WeakPolarHBondContact O-CD2 3.35Å; F136-F140 PolarHBondContact O-N 3.48Å; F140-A142 VanDerWaalsContact C-N 3.31Å; F140-A142 PolarHBondContact O-N 3.23Å; F140-V143 PolarHBondContact O-N 3.43Å; F140-L144 VanDerWaalsContact O-CB 3.26Å; F140-L144 WeakPolarHBondContact O-CB 3.44Å; F140-L144 PolarHBondContact O-N 3.12Å
141	S	94.6	Very high	93.1	Very high	7 Å²	7	17.1 Å²	17.1	5%	0.049	9%	0.094	C	C	.	.	H	α-helix	trans	-63.6	-38.2	174.8	-61.1	0	0	0	0	111.7	I137 N138 L144 Q145	I137-S141 VanDerWaalsContact O-CB 3.24Å; I137-S141 WeakPolarHBondContact O-CB 3.28Å; I137-S141 PolarHBondContact O-N 3.38Å; I137-S141 PolarHBondContact O-OG 3.31Å; N138-S141 PolarHBondContact O-N 2.93Å; S141-L144 PolarHBondContact O-N 3.32Å; S141-Q145 WeakPolarHBondContact O-CB 3.46Å; S141-Q145 WeakPolarHBondContact O-CG 3.41Å; S141-Q145 PolarHBondContact O-N 3.17Å
142	A	93.3	Very high	92.8	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-59.6	-49.1	174	0	0	0	0	0	112.2	L79 F82 T83 N138 S139 F140 G146	L79-A142 HydrophobicContact CD1-CB 3.85Å; F82-A142 HydrophobicContact CB-CB 3.54Å; T83-A142 HydrophobicContact CG2-CB 3.73Å; N138-A142 WeakPolarHBondContact O-CB 3.42Å; N138-A142 PolarHBondContact O-N 2.92Å; S139-A142 WeakPolarHBondContact O-CB 3.32Å; S139-A142 PolarHBondContact O-N 3.1Å; F140-A142 VanDerWaalsContact C-N 3.31Å; F140-A142 PolarHBondContact O-N 3.23Å; A142-G146 PolarHBondContact O-N 2.87Å
143	V	93.3	Very high	92.2	Very high	23 Å²	23	14.8 Å²	14.8	14%	0.139	8%	0.076	C	C	.	.	H	α-helix	trans	-63.8	-43.6	178.2	176.2	0	0	0	0	110.7	F82 R98 S139 F140 S147	F82-V143 HydrophobicContact CB-CG2 4.42Å; F82-V143 HydrophobicContact CD1-CG2 4.14Å; R98-V143 HydrophobicContact CB-CG1 3.98Å; R98-V143 HydrophobicContact CG-CG1 4.28Å; S139-V143 PolarHBondContact O-N 3.11Å; F140-V143 PolarHBondContact O-N 3.43Å; V143-S147 VanDerWaalsContact O-CB 3.26Å; V143-S147 WeakPolarHBondContact O-CB 3.45Å; V143-S147 PolarHBondContact O-N 3.22Å; V143-S147 PolarHBondContact O-OG 3.2Å
144	L	94.1	Very high	91.6	Very high	1 Å²	1	16.8 Å²	16.8	1%	0.005	9%	0.088	C	C	.	.	H	α-helix	trans	-61.1	-54.1	178.5	-180	60	0	0	0	111.8	T25 I99 L103 I106 F140 S141 S147 L148	T25-L144 HydrophobicContact CG2-CD2 3.81Å; T25-L144 HydrophobicContact CG2-CG 3.97Å; I99-L144 HydrophobicContact CB-CD1 4.34Å; I99-L144 HydrophobicContact CG2-CD1 3.82Å; L103-L144 HydrophobicContact CD1-CD1 4.39Å; L103-L144 HydrophobicContact CD2-CD1 4.18Å; L103-L144 HydrophobicContact CD2-CD2 3.62Å; L103-L144 HydrophobicContact CG-CD1 3.85Å; L103-L144 HydrophobicContact CG-CD2 4.09Å; I106-L144 HydrophobicContact CD1-CD2 3.9Å; F140-L144 VanDerWaalsContact O-CB 3.26Å; F140-L144 WeakPolarHBondContact O-CB 3.44Å; F140-L144 PolarHBondContact O-N 3.12Å; S141-L144 PolarHBondContact O-N 3.32Å; L144-S147 PolarHBondContact O-N 3.39Å; L144-L148 HydrophobicContact CD1-CD1 3.58Å; L144-L148 HydrophobicContact CD1-CG 4.25Å; L144-L148 HydrophobicContact CG-CD1 3.82Å; L144-L148 WeakPolarHBondContact O-CB 3.3Å; L144-L148 WeakPolarHBondContact O-CG 3.44Å; L144-L148 PolarHBondContact O-N 3.36Å
145	Q	92.4	Very high	91.1	Very high	14 Å²	14	17.3 Å²	17.3	7%	0.065	9%	0.091	C	C	.	.	H	α-helix	trans	-62.4	-46.6	-179.5	-72.6	-176.5	32.6	0	0	111.2	S141 S147 L148 F149 T435	S141-Q145 WeakPolarHBondContact O-CB 3.46Å; S141-Q145 WeakPolarHBondContact O-CG 3.41Å; S141-Q145 PolarHBondContact O-N 3.17Å; Q145-S147 VanDerWaalsContact C-N 3.31Å; Q145-S147 PolarHBondContact O-N 2.95Å; Q145-L148 PolarHBondContact O-N 3.13Å; Q145-F149 WeakPolarHBondContact O-CD2 3.29Å; Q145-F149 PolarHBondContact O-N 3.23Å; Q145-T435 HydrophobicContact CB-CG2 3.85Å
146	G	89.9	Confident	90.5	Very high	2 Å²	2	17.8 Å²	17.8	2%	0.021	9%	0.094	C	C	.	.	H	α-helix	trans	-64	-36.4	-179.1	0	0	0	0	0	112.7	N86 A142 G150	N86-G146 VanDerWaalsContact ND2-C 3.34Å; N86-G146 WeakPolarHBondContact ND2-CA 3.22Å; A142-G146 PolarHBondContact O-N 2.87Å; G146-G150 PolarHBondContact O-N 2.99Å
147	S	90.8	Very high	89.9	Confident	1 Å²	1	13.3 Å²	13.3	1%	0.007	8%	0.076	C	C	.	.	H	α-helix	trans	-70.7	-42.6	176.5	-55.9	0	0	0	0	112	R98 V143 L144 Q145 G150 Q151	R98-S147 WeakPolarHBondContact CB-OG 3.23Å; R98-S147 PolarHBondContact NH1-OG 3.44Å; V143-S147 VanDerWaalsContact O-CB 3.26Å; V143-S147 WeakPolarHBondContact O-CB 3.45Å; V143-S147 PolarHBondContact O-N 3.22Å; V143-S147 PolarHBondContact O-OG 3.2Å; L144-S147 PolarHBondContact O-N 3.39Å; Q145-S147 VanDerWaalsContact C-N 3.31Å; Q145-S147 PolarHBondContact O-N 2.95Å; S147-G150 PolarHBondContact O-N 3.4Å; S147-Q151 PolarHBondContact O-N 3.28Å
148	L	92.4	Very high	89.5	Confident	0 Å²	0	16.6 Å²	16.6	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-66.6	-41.3	178.3	-74.6	163.8	0	0	0	112.2	L21 T25 I99 L144 Q145 Q151 L152 F163	L21-L148 HydrophobicContact CD1-CD2 4.27Å; L21-L148 HydrophobicContact CD2-CD2 4.48Å; T25-L148 HydrophobicContact CG2-CD1 3.56Å; I99-L148 HydrophobicContact CD1-CD2 3.83Å; I99-L148 HydrophobicContact CD1-CG 4.11Å; I99-L148 HydrophobicContact CG1-CD2 4.44Å; I99-L148 HydrophobicContact CG1-CG 4.32Å; I99-L148 HydrophobicContact CG2-CD2 4.3Å; L144-L148 HydrophobicContact CD1-CD1 3.58Å; L144-L148 HydrophobicContact CD1-CG 4.25Å; L144-L148 HydrophobicContact CG-CD1 3.82Å; L144-L148 WeakPolarHBondContact O-CB 3.3Å; L144-L148 WeakPolarHBondContact O-CG 3.44Å; L144-L148 PolarHBondContact O-N 3.36Å; Q145-L148 PolarHBondContact O-N 3.13Å; L148-Q151 WeakPolarHBondContact O-CB 3.26Å; L148-Q151 PolarHBondContact O-N 3.31Å; L148-L152 WeakPolarHBondContact O-CB 3.46Å; L148-L152 VanDerWaalsContact O-CG 3.24Å; L148-L152 WeakPolarHBondContact O-CG 3.43Å; L148-L152 PolarHBondContact O-N 3.05Å; L148-F163 HydrophobicContact CB-CE2 4.1Å; L148-F163 HydrophobicContact CB-CZ 4.04Å; L148-F163 HydrophobicContact CD1-CE2 3.86Å; L148-F163 HydrophobicContact CD1-CZ 4.04Å; L148-F163 HydrophobicContact CG-CE2 4.42Å
149	F	89.7	Confident	89.3	Confident	6 Å²	6	17.3 Å²	17.3	3%	0.026	10%	0.099	C	C	.	.	H	α-helix	trans	-69	-34.7	174.5	-82	-64.2	0	0	0	112.8	Q145 Q151 L152 G153 F163 L164 M415 T435	Q145-F149 WeakPolarHBondContact O-CD2 3.29Å; Q145-F149 PolarHBondContact O-N 3.23Å; F149-Q151 VanDerWaalsContact C-N 3.34Å; F149-L152 HydrophobicContact CD1-CD1 4.31Å; F149-L152 PolarHBondContact O-N 3.5Å; F149-G153 PolarHBondContact O-N 2.95Å; F149-F163 HydrophobicContact CD2-CE1 4.36Å; F149-F163 AromaticContact CE1-CD1 3.88Å; F149-F163 HydrophobicContact CE1-CD1 3.88Å; F149-F163 AromaticContact CE1-CE1 3.97Å; F149-F163 HydrophobicContact CE1-CE1 3.97Å; F149-F163 HydrophobicContact CE2-CD1 4.45Å; F149-F163 AromaticContact CE2-CE1 3.74Å; F149-F163 HydrophobicContact CE2-CE1 3.74Å; F149-F163 AromaticContact CZ-CD1 3.78Å; F149-F163 HydrophobicContact CZ-CD1 3.78Å; F149-F163 AromaticContact CZ-CE1 3.51Å; F149-F163 HydrophobicContact CZ-CE1 3.51Å; F149-L164 HydrophobicContact CE1-CD1 4.4Å; F149-L164 HydrophobicContact CE1-CD2 4.04Å; F149-L164 HydrophobicContact CE1-CG 4.1Å; F149-L164 HydrophobicContact CZ-CD2 3.68Å; F149-L164 HydrophobicContact CZ-CG 4.17Å; F149-M415 HydrophobicContact CD1-SD 4.47Å; F149-M415 HydrophobicContact CE1-SD 4.28Å; F149-M415 HydrophobicContact CE2-CE 4.48Å; F149-M415 HydrophobicContact CZ-CE 4.48Å; F149-M415 HydrophobicContact CZ-SD 4.48Å; F149-T435 WeakPolarHBondContact CB-OG1 3.34Å; F149-T435 HydrophobicContact CD2-CG2 4.44Å; F149-T435 WeakPolarHBondContact CD2-OG1 3.4Å
150	G	84.9	Confident	89.1	Confident	2 Å²	2	17.2 Å²	17.2	2%	0.021	10%	0.098	C	C	.	.	H	α-helix	trans	-59.5	-45.7	170.1	0	0	0	0	0	111.8	G146 S147 G153 E428	G146-G150 PolarHBondContact O-N 2.99Å; S147-G150 PolarHBondContact O-N 3.4Å; G150-G153 PolarHBondContact O-N 2.86Å; G150-E428 WeakPolarHBondContact CA-O 3.37Å; G150-E428 WeakPolarHBondContact O-CA 3.28Å
151	Q	86.2	Confident	88.9	Confident	8 Å²	8	13.9 Å²	13.9	4%	0.037	8%	0.084	C	C	.	.	H	α-helix	trans	-61.6	-49.2	175.8	-168.9	-178.4	45.1	0	0	111.7	E95 S147 L148 F149 G153 T154 L223	E95-Q151 WeakPolarHBondContact OE1-CB 3.32Å; E95-Q151 WeakPolarHBondContact OE1-CG 3.4Å; E95-Q151 PolarHBondContact OE1-NE2 3.47Å; S147-Q151 PolarHBondContact O-N 3.28Å; L148-Q151 WeakPolarHBondContact O-CB 3.26Å; L148-Q151 PolarHBondContact O-N 3.31Å; F149-Q151 VanDerWaalsContact C-N 3.34Å; Q151-G153 PolarHBondContact O-N 3.49Å; Q151-T154 PolarHBondContact O-N 2.97Å; Q151-T154 VanDerWaalsContact O-N 3.09Å; Q151-T154 PolarHBondContact O-OG1 2.93Å; Q151-L223 HydrophobicContact CG-CD2 3.31Å
152	L	88.9	Confident	88.8	Confident	0 Å²	0	16 Å²	16	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-62.8	-28.5	179.6	-76.6	166.8	0	0	0	113.3	F18 L148 F149 T154 M155 F163	F18-L152 HydrophobicContact CD1-CD1 4.38Å; F18-L152 HydrophobicContact CD1-CD2 3.51Å; F18-L152 HydrophobicContact CD1-CG 4.05Å; F18-L152 HydrophobicContact CD2-CD2 4.3Å; F18-L152 HydrophobicContact CE1-CD2 3.66Å; F18-L152 HydrophobicContact CE1-CG 3.97Å; F18-L152 HydrophobicContact CE2-CD2 4.44Å; F18-L152 HydrophobicContact CG-CD2 3.86Å; F18-L152 HydrophobicContact CZ-CD2 4.13Å; L148-L152 WeakPolarHBondContact O-CB 3.46Å; L148-L152 VanDerWaalsContact O-CG 3.24Å; L148-L152 WeakPolarHBondContact O-CG 3.43Å; L148-L152 PolarHBondContact O-N 3.05Å; F149-L152 HydrophobicContact CD1-CD1 4.31Å; F149-L152 PolarHBondContact O-N 3.5Å; L152-T154 PolarHBondContact O-N 3.36Å; L152-M155 PolarHBondContact O-N 3.36Å; L152-F163 HydrophobicContact CD1-CB 3.55Å; L152-F163 HydrophobicContact CD1-CD1 3.67Å; L152-F163 HydrophobicContact CD1-CD2 3.81Å; L152-F163 HydrophobicContact CD1-CE1 4.3Å; L152-F163 HydrophobicContact CD1-CE2 4.43Å; L152-F163 HydrophobicContact CD1-CG 3.39Å; L152-F163 HydrophobicContact CD2-CB 4.47Å
153	G	82.6	Confident	88.9	Confident	4 Å²	4	16 Å²	16	4%	0.041	9%	0.094	C	C	.	.	H	α-helix	trans	-60.3	-26.8	174.1	0	0	0	0	0	113.3	F149 G150 Q151 R427	F149-G153 PolarHBondContact O-N 2.95Å; G150-G153 PolarHBondContact O-N 2.86Å; Q151-G153 PolarHBondContact O-N 3.49Å; G153-R427 VanDerWaalsContact O-CB 3.24Å; G153-R427 WeakPolarHBondContact O-CB 3.27Å; G153-R427 WeakPolarHBondContact O-CD 3.2Å
154	T	82.4	Confident	89	Confident	47 Å²	47	14.9 Å²	14.9	29%	0.288	9%	0.087	S	C	.	.	T	Hydrogen-bonded Turn	trans	-82.4	-15.3	177.1	68.8	0	0	0	0	113.4	Q151 L152 E428	Q151-T154 PolarHBondContact O-N 2.97Å; Q151-T154 VanDerWaalsContact O-N 3.09Å; Q151-T154 PolarHBondContact O-OG1 2.93Å; L152-T154 PolarHBondContact O-N 3.36Å; T154-E428 HydrophobicContact CG2-CB 4.48Å
155	M	84.4	Confident	89	Confident	11 Å²	11	15.3 Å²	15.3	5%	0.054	9%	0.09	C	C	.	.	S	Bend	trans	-95.9	165.3	-178.7	-68.7	-165.5	178.6	0	0	112.2	F18 L152 Y159 L223	F18-M155 HydrophobicContact CD2-SD 4.29Å; F18-M155 HydrophobicContact CE2-CE 3.69Å; F18-M155 HydrophobicContact CE2-SD 3.39Å; F18-M155 WeakPolarHBondContact CE2-SD 3.32Å; F18-M155 HydrophobicContact CZ-CE 3.77Å; F18-M155 HydrophobicContact CZ-SD 3.74Å; L152-M155 PolarHBondContact O-N 3.36Å; M155-Y159 HydrophobicContact CB-CD2 4.22Å; M155-Y159 HydrophobicContact SD-CG 4.32Å; M155-L223 HydrophobicContact CE-CD1 3.81Å; M155-L223 HydrophobicContact CE-CD2 3.48Å; M155-L223 VanDerWaalsContact CE-CD2 3.48Å; M155-L223 HydrophobicContact CE-CG 3.47Å; M155-L223 VanDerWaalsContact CE-CG 3.47Å
156	P	85.3	Confident	89.2	Confident	48 Å²	48	14.6 Å²	14.6	31%	0.312	9%	0.087	S	C	.	.			trans	-54.2	141.5	168.5	-25.1	34.5	0	0	0	111.7	T158 Y159 Y222	P156-T158 PolarHBondContact O-N 2.99Å; P156-Y159 HydrophobicContact CB-CD2 4.12Å; P156-Y159 HydrophobicContact CB-CE2 4.32Å; P156-Y159 HydrophobicContact CG-CD2 4.28Å; P156-Y159 HydrophobicContact CG-CE2 4.19Å; P156-Y159 WeakPolarHBondContact O-CD2 3.5Å; P156-Y159 PolarHBondContact O-N 3.47Å; P156-Y222 HydrophobicContact CG-CE1 4.21Å
157	S	82.6	Confident	89.5	Confident	19 Å²	19	14.8 Å²	14.8	13%	0.133	9%	0.088	C	C	.	.	H	α-helix	trans	-57.1	-24.6	-174.6	59.8	0	0	0	0	114.2	Y159 S160 T161 R420	S157-Y159 PolarHBondContact O-N 3.13Å; S157-S160 WeakPolarHBondContact O-CA 3.12Å; S157-S160 VanDerWaalsContact O-CB 3.31Å; S157-S160 WeakPolarHBondContact O-CB 3.48Å; S157-S160 PolarHBondContact O-N 3.1Å; S157-T161 PolarHBondContact O-N 3.3Å; S157-R420 PolarHBondContact OG-NH2 2.89Å
158	T	86.7	Confident	89.6	Confident	71 Å²	71	14.9 Å²	14.9	44%	0.436	9%	0.088	S	C	.	.	H	α-helix	trans	-55.1	-35.8	174.1	-51.9	0	0	0	0	112.1	P156 S160 T161 L162	P156-T158 PolarHBondContact O-N 2.99Å; T158-S160 VanDerWaalsContact C-N 3.35Å; T158-T161 PolarHBondContact O-N 2.99Å; T158-T161 PolarHBondContact O-OG1 3.03Å; T158-L162 HydrophobicContact CG2-CD1 3.89Å; T158-L162 VanDerWaalsContact O-CD1 3.28Å; T158-L162 WeakPolarHBondContact O-CD1 3.35Å; T158-L162 PolarHBondContact O-N 3.4Å
159	Y	89.9	Confident	89.8	Confident	22 Å²	22	16.5 Å²	16.5	9%	0.086	10%	0.097	C	C	.	.	H	α-helix	trans	-71.1	-32.7	176.8	-66.3	-80.1	0	0	0	112.4	D9 V14 F18 M155 P156 S157 F163 F218	D9-Y159 WeakPolarHBondContact CB-OH 3.29Å; D9-Y159 PolarHBondContact OD2-OH 3.41Å; V14-Y159 HydrophobicContact CB-CE1 3.91Å; V14-Y159 HydrophobicContact CG1-CD1 4.01Å; V14-Y159 HydrophobicContact CG1-CE1 3.68Å; F18-Y159 HydrophobicContact CD2-CD1 4.09Å; M155-Y159 HydrophobicContact CB-CD2 4.22Å; M155-Y159 HydrophobicContact SD-CG 4.32Å; P156-Y159 HydrophobicContact CB-CD2 4.12Å; P156-Y159 HydrophobicContact CB-CE2 4.32Å; P156-Y159 HydrophobicContact CG-CD2 4.28Å; P156-Y159 HydrophobicContact CG-CE2 4.19Å; P156-Y159 WeakPolarHBondContact O-CD2 3.5Å; P156-Y159 PolarHBondContact O-N 3.47Å; S157-Y159 PolarHBondContact O-N 3.13Å; Y159-F163 WeakPolarHBondContact O-CB 3.44Å; Y159-F163 PolarHBondContact O-N 3.49Å; Y159-F218 HydrophobicContact CD2-CE1 4.45Å; Y159-F218 HydrophobicContact CE1-CE1 4.31Å; Y159-F218 AromaticContact CE2-CE1 3.53Å; Y159-F218 HydrophobicContact CE2-CE1 3.53Å; Y159-F218 AromaticContact CE2-CZ 3.57Å; Y159-F218 HydrophobicContact CE2-CZ 3.57Å; Y159-F218 AromaticContact CZ-CE1 3.45Å; Y159-F218 VanDerWaalsContact CZ-CE1 3.45Å; Y159-F218 AromaticContact CZ-CZ 3.69Å; Y159-F218 VanDerWaalsContact OH-CE1 3.28Å; Y159-F218 WeakPolarHBondContact OH-CE1 3.35Å; Y159-F218 VanDerWaalsContact OH-CZ 3.26Å; Y159-F218 WeakPolarHBondContact OH-CZ 3.43Å
160	S	90.8	Very high	90.1	Very high	5 Å²	5	16.2 Å²	16.2	4%	0.035	10%	0.096	C	C	.	.	H	α-helix	trans	-64.2	-44.1	172.1	-64	0	0	0	0	110.7	S157 T158 F163 L164	S157-S160 WeakPolarHBondContact O-CA 3.12Å; S157-S160 VanDerWaalsContact O-CB 3.31Å; S157-S160 WeakPolarHBondContact O-CB 3.48Å; S157-S160 PolarHBondContact O-N 3.1Å; T158-S160 VanDerWaalsContact C-N 3.35Å; S160-F163 PolarHBondContact O-N 3.2Å; S160-L164 WeakPolarHBondContact O-CB 3.37Å; S160-L164 VanDerWaalsContact O-CD1 3.29Å; S160-L164 WeakPolarHBondContact O-CD1 3.01Å; S160-L164 VanDerWaalsContact O-CG 3.3Å; S160-L164 WeakPolarHBondContact O-CG 3.39Å; S160-L164 PolarHBondContact O-N 2.94Å
161	T	91.6	Very high	90.6	Very high	0 Å²	0	16.1 Å²	16.1	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-66.1	-39	178.5	65.1	0	0	0	0	112.4	S157 T158 L164 S165 S349 C416	S157-T161 PolarHBondContact O-N 3.3Å; T158-T161 PolarHBondContact O-N 2.99Å; T158-T161 PolarHBondContact O-OG1 3.03Å; T161-L164 PolarHBondContact O-N 3.36Å; T161-S165 WeakPolarHBondContact O-CB 3.43Å; T161-S165 PolarHBondContact O-N 3.25Å; T161-S349 VanDerWaalsContact CB-OG 3.27Å; T161-S349 WeakPolarHBondContact CB-OG 3.47Å; T161-S349 WeakPolarHBondContact OG1-CB 3.09Å; T161-S349 PolarHBondContact OG1-OG 2.93Å; T161-C416 WeakPolarHBondContact CG2-SG 3.37Å
162	L	93.6	Very high	91.1	Very high	51 Å²	51	16.6 Å²	16.6	27%	0.267	10%	0.098	S	C	.	.	H	α-helix	trans	-62.4	-45.3	173.3	-91.5	130.1	0	0	0	112	F19 T158 S165 G166	F19-L162 HydrophobicContact CB-CD2 4.31Å; F19-L162 WeakPolarHBondContact CD2-O 3.28Å; T158-L162 HydrophobicContact CG2-CD1 3.89Å; T158-L162 VanDerWaalsContact O-CD1 3.28Å; T158-L162 WeakPolarHBondContact O-CD1 3.35Å; T158-L162 PolarHBondContact O-N 3.4Å; L162-S165 PolarHBondContact O-N 2.96Å; L162-G166 PolarHBondContact O-N 2.88Å
163	F	95.3	Very high	91.4	Very high	0 Å²	0	21 Å²	21	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-59	-48.3	175	177	-93	0	0	0	112	F18 L21 G22 T25 L148 F149 L152 Y159 S160 S165 G166 Q167	F18-F163 HydrophobicContact CB-CB 4.42Å; F18-F163 HydrophobicContact CD1-CD2 4.44Å; F18-F163 WeakPolarHBondContact O-CA 3.44Å; F18-F163 VanDerWaalsContact O-CD2 3.3Å; F18-F163 WeakPolarHBondContact O-CD2 3.3Å; L21-F163 HydrophobicContact CB-CD2 4.3Å; L21-F163 HydrophobicContact CB-CE2 4.15Å; G22-F163 VanDerWaalsContact CA-CD2 3.46Å; G22-F163 WeakPolarHBondContact CA-O 3.43Å; G22-F163 VanDerWaalsContact N-CE2 3.34Å; T25-F163 HydrophobicContact CG2-CE2 4.27Å; T25-F163 HydrophobicContact CG2-CZ 3.98Å; L148-F163 HydrophobicContact CB-CE2 4.1Å; L148-F163 HydrophobicContact CB-CZ 4.04Å; L148-F163 HydrophobicContact CD1-CE2 3.86Å; L148-F163 HydrophobicContact CD1-CZ 4.04Å; L148-F163 HydrophobicContact CG-CE2 4.42Å; F149-F163 HydrophobicContact CD2-CE1 4.36Å; F149-F163 AromaticContact CE1-CD1 3.88Å; F149-F163 HydrophobicContact CE1-CD1 3.88Å; F149-F163 AromaticContact CE1-CE1 3.97Å; F149-F163 HydrophobicContact CE1-CE1 3.97Å; F149-F163 HydrophobicContact CE2-CD1 4.45Å; F149-F163 AromaticContact CE2-CE1 3.74Å; F149-F163 HydrophobicContact CE2-CE1 3.74Å; F149-F163 AromaticContact CZ-CD1 3.78Å; F149-F163 HydrophobicContact CZ-CD1 3.78Å; F149-F163 AromaticContact CZ-CE1 3.51Å; F149-F163 HydrophobicContact CZ-CE1 3.51Å; L152-F163 HydrophobicContact CD1-CB 3.55Å; L152-F163 HydrophobicContact CD1-CD1 3.67Å; L152-F163 HydrophobicContact CD1-CD2 3.81Å; L152-F163 HydrophobicContact CD1-CE1 4.3Å; L152-F163 HydrophobicContact CD1-CE2 4.43Å; L152-F163 HydrophobicContact CD1-CG 3.39Å; L152-F163 HydrophobicContact CD2-CB 4.47Å; Y159-F163 WeakPolarHBondContact O-CB 3.44Å; Y159-F163 PolarHBondContact O-N 3.49Å; S160-F163 PolarHBondContact O-N 3.2Å; F163-S165 VanDerWaalsContact C-N 3.34Å; F163-S165 PolarHBondContact O-N 2.79Å; F163-G166 PolarHBondContact O-N 3.36Å; F163-Q167 HydrophobicContact CE1-CG 4.27Å; F163-Q167 PolarHBondContact O-N 3.45Å; F163-Q167 VanDerWaalsContact O-N 3.09Å
164	L	94.1	Very high	91.9	Very high	0 Å²	0	21 Å²	21	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-63.5	-37.8	177	-73.7	156.5	0	0	0	112	F149 S160 T161 G166 Q167 G168 R345 S412 M415	F149-L164 HydrophobicContact CE1-CD1 4.4Å; F149-L164 HydrophobicContact CE1-CD2 4.04Å; F149-L164 HydrophobicContact CE1-CG 4.1Å; F149-L164 HydrophobicContact CZ-CD2 3.68Å; F149-L164 HydrophobicContact CZ-CG 4.17Å; S160-L164 WeakPolarHBondContact O-CB 3.37Å; S160-L164 VanDerWaalsContact O-CD1 3.29Å; S160-L164 WeakPolarHBondContact O-CD1 3.01Å; S160-L164 VanDerWaalsContact O-CG 3.3Å; S160-L164 WeakPolarHBondContact O-CG 3.39Å; S160-L164 PolarHBondContact O-N 2.94Å; T161-L164 PolarHBondContact O-N 3.36Å; L164-G166 VanDerWaalsContact C-N 3.33Å; L164-G166 PolarHBondContact O-N 2.85Å; L164-Q167 VanDerWaalsContact O-CB 3.32Å; L164-Q167 WeakPolarHBondContact O-CB 3.44Å; L164-Q167 PolarHBondContact O-N 3.46Å; L164-G168 PolarHBondContact O-N 2.96Å; L164-G168 VanDerWaalsContact O-N 3.08Å; L164-R345 VanDerWaalsContact CD2-NH1 3.31Å; L164-R345 VanDerWaalsContact O-CD 3.25Å; L164-R345 WeakPolarHBondContact O-CD 3.47Å; L164-S412 WeakPolarHBondContact CB-OG 3.35Å; L164-M415 HydrophobicContact CD1-CB 3.8Å; L164-M415 HydrophobicContact CD1-CG 4.44Å; L164-M415 HydrophobicContact CD2-CG 4.37Å
165	S	95	Very high	92.5	Very high	10 Å²	10	18.9 Å²	18.9	7%	0.07	10%	0.104	C	C	.	.	H	α-helix	trans	-61.6	-42.1	173.5	-177.6	0	0	0	0	111.2	T161 L162 F163 Q167 G168 L169 W342 S346	T161-S165 WeakPolarHBondContact O-CB 3.43Å; T161-S165 PolarHBondContact O-N 3.25Å; L162-S165 PolarHBondContact O-N 2.96Å; F163-S165 VanDerWaalsContact C-N 3.34Å; F163-S165 PolarHBondContact O-N 2.79Å; S165-Q167 VanDerWaalsContact C-N 3.31Å; S165-Q167 PolarHBondContact O-N 2.62Å; S165-G168 PolarHBondContact O-N 2.93Å; S165-G168 VanDerWaalsContact O-N 3.09Å; S165-L169 PolarHBondContact O-N 3.13Å; S165-W342 VanDerWaalsContact O-CD1 3.24Å; S165-W342 PolarHBondContact OG-NE1 2.92Å; S165-W342 VanDerWaalsContact OG-NE1 3.08Å; S165-S346 PolarHBondContact OG-OG 2.93Å
166	G	95.9	Very high	93	Very high	0 Å²	0	21.8 Å²	21.8	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-57	-42.3	172.6	0	0	0	0	0	113	F19 L23 L162 F163 L164 G168 L169 A170	F19-G166 WeakPolarHBondContact O-CA 3.13Å; L23-G166 WeakPolarHBondContact CA-O 3.3Å; L23-G166 WeakPolarHBondContact CD1-O 3.41Å; L162-G166 PolarHBondContact O-N 2.88Å; F163-G166 PolarHBondContact O-N 3.36Å; L164-G166 VanDerWaalsContact C-N 3.33Å; L164-G166 PolarHBondContact O-N 2.85Å; G166-G168 PolarHBondContact O-N 3.37Å; G166-L169 PolarHBondContact O-N 3.18Å; G166-A170 PolarHBondContact O-N 3.06Å
167	Q	95.6	Very high	93.3	Very high	6 Å²	6	20.4 Å²	20.4	3%	0.028	11%	0.112	C	C	.	.	H	α-helix	trans	-59.5	-41.9	173.3	-76.8	-170	-24.5	0	0	112.9	G22 T25 L26 F163 L164 S165 A170	G22-Q167 VanDerWaalsContact O-CG 3.26Å; G22-Q167 WeakPolarHBondContact O-CG 3.44Å; T25-Q167 PolarHBondContact OG1-NE2 3.43Å; T25-Q167 VanDerWaalsContact OG1-NE2 3.07Å; L26-Q167 HydrophobicContact CD1-CB 3.63Å; L26-Q167 HydrophobicContact CD1-CG 3.86Å; L26-Q167 HydrophobicContact CG-CB 4.16Å; L26-Q167 HydrophobicContact CG-CG 3.9Å; F163-Q167 HydrophobicContact CE1-CG 4.27Å; F163-Q167 PolarHBondContact O-N 3.45Å; F163-Q167 VanDerWaalsContact O-N 3.09Å; L164-Q167 VanDerWaalsContact O-CB 3.32Å; L164-Q167 WeakPolarHBondContact O-CB 3.44Å; L164-Q167 PolarHBondContact O-N 3.46Å; S165-Q167 VanDerWaalsContact C-N 3.31Å; S165-Q167 PolarHBondContact O-N 2.62Å; Q167-A170 WeakPolarHBondContact O-CB 3.46Å; Q167-A170 PolarHBondContact O-N 3.5Å
168	G	94.2	Very high	93.7	Very high	2 Å²	2	21 Å²	21	2%	0.021	11%	0.113	C	C	.	.	H	α-helix	trans	-63.1	-41.8	174.8	0	0	0	0	0	112.7	L164 S165 G166 A170 G171 I172	L164-G168 PolarHBondContact O-N 2.96Å; L164-G168 VanDerWaalsContact O-N 3.08Å; S165-G168 PolarHBondContact O-N 2.93Å; S165-G168 VanDerWaalsContact O-N 3.09Å; G166-G168 PolarHBondContact O-N 3.37Å; G168-A170 PolarHBondContact O-N 3.47Å; G168-G171 PolarHBondContact O-N 3.13Å; G168-G171 VanDerWaalsContact O-N 3.08Å; G168-I172 PolarHBondContact O-N 2.73Å
169	L	96	Very high	94	Very high	34 Å²	34	18.8 Å²	18.8	18%	0.178	10%	0.098	C	C	.	.	H	α-helix	trans	-62.1	-32.6	178.4	-175.1	65.2	0	0	0	112.3	F19 L23 S165 G166 G171 I172 F173	F19-L169 HydrophobicContact CE1-CD2 3.72Å; F19-L169 HydrophobicContact CZ-CB 4.21Å; F19-L169 HydrophobicContact CZ-CD2 3.53Å; F19-L169 HydrophobicContact CZ-CG 4.48Å; L23-L169 HydrophobicContact CD1-CB 3.99Å; L23-L169 HydrophobicContact CD1-CD2 4.19Å; L23-L169 HydrophobicContact CD1-CG 4.04Å; S165-L169 PolarHBondContact O-N 3.13Å; G166-L169 PolarHBondContact O-N 3.18Å; L169-G171 PolarHBondContact O-N 3.48Å; L169-I172 HydrophobicContact CD1-CB 4.36Å; L169-I172 HydrophobicContact CD1-CD1 4.12Å; L169-I172 WeakPolarHBondContact O-CB 3.37Å; L169-I172 PolarHBondContact O-N 2.77Å; L169-I172 VanDerWaalsContact O-N 3.11Å; L169-F173 HydrophobicContact CD2-CE2 3.93Å; L169-F173 HydrophobicContact CD2-CZ 4.09Å; L169-F173 HydrophobicContact CG-CD2 4.34Å; L169-F173 HydrophobicContact CG-CE2 3.96Å; L169-F173 HydrophobicContact CG-CZ 4.23Å; L169-F173 PolarHBondContact O-N 3.45Å
170	A	96.3	Very high	94	Very high	0 Å²	0	23.6 Å²	23.6	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-59.1	-35.4	176.1	0	0	0	0	0	112.2	L23 L26 L27 G166 Q167 G168 A174	L23-A170 HydrophobicContact CD1-CB 3.86Å; L26-A170 HydrophobicContact CB-CB 4.1Å; L27-A170 HydrophobicContact CB-CB 4.05Å; L27-A170 HydrophobicContact CD1-CB 4.03Å; G166-A170 PolarHBondContact O-N 3.06Å; Q167-A170 WeakPolarHBondContact O-CB 3.46Å; Q167-A170 PolarHBondContact O-N 3.5Å; G168-A170 PolarHBondContact O-N 3.47Å; A170-A174 PolarHBondContact O-N 3.23Å; A170-A174 VanDerWaalsContact O-N 3.16Å
171	G	95.1	Very high	94	Very high	1 Å²	1	24.6 Å²	24.6	1%	0.01	13%	0.132	C	C	.	.	H	α-helix	trans	-68	-39.6	175.7	0	0	0	0	0	112.8	N30 G168 L169 A174 A175 N338	N30-G171 VanDerWaalsContact ND2-CA 3.29Å; N30-G171 WeakPolarHBondContact ND2-CA 3.32Å; N30-G171 PolarHBondContact ND2-N 3.37Å; N30-G171 VanDerWaalsContact ND2-N 3.19Å; G168-G171 PolarHBondContact O-N 3.13Å; G168-G171 VanDerWaalsContact O-N 3.08Å; L169-G171 PolarHBondContact O-N 3.48Å; G171-A174 PolarHBondContact O-N 3.35Å; G171-A175 WeakPolarHBondContact O-CB 3.44Å; G171-A175 PolarHBondContact O-N 2.89Å; G171-N338 WeakPolarHBondContact CA-OD1 3.31Å
172	I	96.7	Very high	93.7	Very high	18 Å²	18	28.3 Å²	28.3	9%	0.092	15%	0.15	C	C	.	.	H	α-helix	trans	-62.3	-46.2	175.1	-60.4	175.3	0	0	0	110	G168 L169 A174 A175 L176 L335 N338 I339 W342	G168-I172 PolarHBondContact O-N 2.73Å; L169-I172 HydrophobicContact CD1-CB 4.36Å; L169-I172 HydrophobicContact CD1-CD1 4.12Å; L169-I172 WeakPolarHBondContact O-CB 3.37Å; L169-I172 PolarHBondContact O-N 2.77Å; L169-I172 VanDerWaalsContact O-N 3.11Å; I172-A174 VanDerWaalsContact C-N 3.32Å; I172-A174 PolarHBondContact O-N 3.07Å; I172-A175 PolarHBondContact O-N 3.31Å; I172-L176 HydrophobicContact CG2-CD1 3.84Å; I172-L176 HydrophobicContact CG2-CG 4.17Å; I172-L176 WeakPolarHBondContact O-CB 3.46Å; I172-L176 WeakPolarHBondContact O-CG 3.26Å; I172-L176 PolarHBondContact O-N 3.48Å; I172-L335 HydrophobicContact CG2-CD1 4.48Å; I172-N338 HydrophobicContact CG1-CB 4Å; I172-I339 HydrophobicContact CD1-CG1 4.15Å; I172-I339 HydrophobicContact CG1-CG1 4.15Å; I172-W342 HydrophobicContact CD1-CB 3.75Å; I172-W342 HydrophobicContact CD1-CD2 3.88Å; I172-W342 HydrophobicContact CD1-CE3 3.86Å; I172-W342 HydrophobicContact CD1-CG 3.84Å; I172-W342 HydrophobicContact CG1-CB 4.46Å
173	F	95.8	Very high	93.4	Very high	91 Å²	91	29.3 Å²	29.3	40%	0.399	17%	0.166	S	C	.	.	H	α-helix	trans	-60.8	-40.4	177.8	-74.6	-36	0	0	0	112.8	L23 L27 F31 L169 A177	L23-F173 HydrophobicContact CD1-CD2 3.85Å; L23-F173 HydrophobicContact CD1-CE2 3.89Å; L23-F173 HydrophobicContact CD2-CE2 4.11Å; L27-F173 HydrophobicContact CD1-CB 3.97Å; L27-F173 HydrophobicContact CD1-CD2 4.12Å; F31-F173 HydrophobicContact CE2-CB 4.11Å; F31-F173 HydrophobicContact CZ-CB 4.44Å; L169-F173 HydrophobicContact CD2-CE2 3.93Å; L169-F173 HydrophobicContact CD2-CZ 4.09Å; L169-F173 HydrophobicContact CG-CD2 4.34Å; L169-F173 HydrophobicContact CG-CE2 3.96Å; L169-F173 HydrophobicContact CG-CZ 4.23Å; L169-F173 PolarHBondContact O-N 3.45Å; F173-A177 VanDerWaalsContact O-CB 3.26Å; F173-A177 WeakPolarHBondContact O-CB 3.4Å; F173-A177 PolarHBondContact O-N 3.25Å
174	A	93.6	Very high	93	Very high	4 Å²	4	32.6 Å²	32.6	3%	0.033	19%	0.189	C	C	.	.	H	α-helix	trans	-64.7	-44.6	176	0	0	0	0	0	112	N30 F31 A170 G171 I172 L176 A177 M178	N30-A174 HydrophobicContact CB-CB 3.66Å; F31-A174 HydrophobicContact CD2-CB 3.84Å; F31-A174 HydrophobicContact CE2-CB 3.93Å; A170-A174 PolarHBondContact O-N 3.23Å; A170-A174 VanDerWaalsContact O-N 3.16Å; G171-A174 PolarHBondContact O-N 3.35Å; I172-A174 VanDerWaalsContact C-N 3.32Å; I172-A174 PolarHBondContact O-N 3.07Å; A174-L176 PolarHBondContact O-N 2.92Å; A174-A177 PolarHBondContact O-N 3.49Å; A174-M178 PolarHBondContact O-N 3.05Å
175	A	94.3	Very high	92.2	Very high	3 Å²	3	36 Å²	36	3%	0.025	22%	0.223	C	C	.	.	H	α-helix	trans	-64.9	-39.5	177.5	0	0	0	0	0	112.7	G171 I172 M178 L179 F334 L335	G171-A175 WeakPolarHBondContact O-CB 3.44Å; G171-A175 PolarHBondContact O-N 2.89Å; I172-A175 PolarHBondContact O-N 3.31Å; A175-M178 WeakPolarHBondContact O-CB 3.47Å; A175-M178 PolarHBondContact O-N 3.08Å; A175-L179 WeakPolarHBondContact O-CG 3.39Å; A175-L179 PolarHBondContact O-N 3.49Å; A175-L179 VanDerWaalsContact O-N 3.08Å; A175-F334 HydrophobicContact CB-CB 4.46Å; A175-L335 HydrophobicContact CB-CB 4.17Å; A175-L335 HydrophobicContact CB-CD1 3.99Å
176	L	94.7	Very high	91.6	Very high	73 Å²	73	38.5 Å²	38.5	38%	0.382	24%	0.239	S	C	.	.	H	α-helix	trans	-66.7	-41.9	173.8	-71	177.1	0	0	0	111.6	I172 A174 M178 L179 L180 L335	I172-L176 HydrophobicContact CG2-CD1 3.84Å; I172-L176 HydrophobicContact CG2-CG 4.17Å; I172-L176 WeakPolarHBondContact O-CB 3.46Å; I172-L176 WeakPolarHBondContact O-CG 3.26Å; I172-L176 PolarHBondContact O-N 3.48Å; A174-L176 PolarHBondContact O-N 2.92Å; L176-M178 VanDerWaalsContact C-N 3.31Å; L176-M178 PolarHBondContact O-N 3.46Å; L176-L179 PolarHBondContact O-N 3.05Å; L176-L180 WeakPolarHBondContact O-CB 3.47Å; L176-L180 VanDerWaalsContact O-CG 3.28Å; L176-L180 WeakPolarHBondContact O-CG 3.32Å; L176-L180 PolarHBondContact O-N 2.94Å; L176-L335 HydrophobicContact CD2-CD1 3.88Å; L176-L335 HydrophobicContact CG-CD1 4.12Å
177	A	92.4	Very high	91.1	Very high	19 Å²	19	42.4 Å²	42.4	16%	0.157	26%	0.259	C	S	.	.	H	α-helix	trans	-60.9	-41.7	176.1	0	0	0	0	0	111.4	F31 F173 A174 L180 S181 Y195	F31-A177 HydrophobicContact CE1-CB 3.54Å; F31-A177 HydrophobicContact CZ-CB 3.68Å; F173-A177 VanDerWaalsContact O-CB 3.26Å; F173-A177 WeakPolarHBondContact O-CB 3.4Å; F173-A177 PolarHBondContact O-N 3.25Å; A174-A177 PolarHBondContact O-N 3.49Å; A177-L180 PolarHBondContact O-N 3.36Å; A177-S181 WeakPolarHBondContact O-CB 3.48Å; A177-S181 PolarHBondContact O-N 3.32Å; A177-Y195 HydrophobicContact CB-CD1 4.2Å; A177-Y195 HydrophobicContact CB-CE1 3.85Å
178	M	90.9	Very high	90.5	Very high	30 Å²	30	45 Å²	45	15%	0.148	28%	0.281	C	S	.	.	H	α-helix	trans	-56.8	-49.8	172.8	-171.9	175.1	50.6	0	0	111.9	T34 A174 A175 L176 S181 M182 Y195 P330 F334	T34-M178 HydrophobicContact CG2-CB 3.62Å; T34-M178 HydrophobicContact CG2-CG 4.03Å; T34-M178 HydrophobicContact CG2-SD 4.46Å; A174-M178 PolarHBondContact O-N 3.05Å; A175-M178 WeakPolarHBondContact O-CB 3.47Å; A175-M178 PolarHBondContact O-N 3.08Å; L176-M178 VanDerWaalsContact C-N 3.31Å; L176-M178 PolarHBondContact O-N 3.46Å; M178-S181 PolarHBondContact O-N 3.09Å; M178-M182 HydrophobicContact CG-SD 4.28Å; M178-M182 WeakPolarHBondContact O-CG 3.34Å; M178-M182 PolarHBondContact O-N 3.07Å; M178-Y195 WeakPolarHBondContact CA-OH 3.18Å; M178-P330 HydrophobicContact CE-CB 3.82Å; M178-P330 HydrophobicContact CE-CG 4.29Å; M178-F334 HydrophobicContact CE-CB 3.72Å; M178-F334 HydrophobicContact CE-CD2 3.73Å; M178-F334 HydrophobicContact CE-CG 3.86Å; M178-F334 HydrophobicContact SD-CD2 4.49Å
179	L	91.8	Very high	90.1	Very high	25 Å²	25	49.2 Å²	49.2	13%	0.131	30%	0.301	C	S	.	.	H	α-helix	trans	-63.2	-43	179.6	-76.1	169.6	0	0	0	112.4	A175 L176 M182 A183 F327 P330 I331 L335	A175-L179 WeakPolarHBondContact O-CG 3.39Å; A175-L179 PolarHBondContact O-N 3.49Å; A175-L179 VanDerWaalsContact O-N 3.08Å; L176-L179 PolarHBondContact O-N 3.05Å; L179-M182 PolarHBondContact O-N 3.04Å; L179-A183 VanDerWaalsContact O-CB 3.27Å; L179-A183 WeakPolarHBondContact O-CB 3.24Å; L179-A183 PolarHBondContact O-N 3.27Å; L179-F327 HydrophobicContact CD2-CD1 3.98Å; L179-P330 HydrophobicContact CD2-CB 3.44Å; L179-P330 VanDerWaalsContact CD2-CB 3.44Å; L179-P330 HydrophobicContact CG-CB 4.14Å; L179-I331 HydrophobicContact CD1-CG1 4.3Å; L179-I331 HydrophobicContact CD2-CG1 3.78Å; L179-L335 HydrophobicContact CD1-CB 4.32Å; L179-L335 HydrophobicContact CD1-CD2 3.75Å; L179-L335 HydrophobicContact CD1-CG 4.47Å
180	L	91.1	Very high	89.7	Confident	123 Å²	123	50.8 Å²	50.8	64%	0.644	31%	0.312	S	S	*	.	H	α-helix	trans	-65.3	-41.1	178.3	-70.7	172.2	0	0	0	111.8	L176 A177 A183 S184	L176-L180 WeakPolarHBondContact O-CB 3.47Å; L176-L180 VanDerWaalsContact O-CG 3.28Å; L176-L180 WeakPolarHBondContact O-CG 3.32Å; L176-L180 PolarHBondContact O-N 2.94Å; A177-L180 PolarHBondContact O-N 3.36Å; L180-A183 PolarHBondContact O-N 3.29Å; L180-S184 WeakPolarHBondContact O-CB 3.41Å; L180-S184 PolarHBondContact O-N 3.18Å; L180-S184 PolarHBondContact O-OG 2.92Å
181	S	89.7	Confident	89.3	Confident	26 Å²	26	51.4 Å²	51.4	18%	0.182	32%	0.316	C	S	.	.	H	α-helix	trans	-61.2	-47.2	173.8	172.8	0	0	0	0	111.5	A177 M178 A183 S184 G185 S191 Y195	A177-S181 WeakPolarHBondContact O-CB 3.48Å; A177-S181 PolarHBondContact O-N 3.32Å; M178-S181 PolarHBondContact O-N 3.09Å; S181-A183 PolarHBondContact O-N 3.36Å; S181-S184 PolarHBondContact O-N 3.25Å; S181-S184 PolarHBondContact O-OG 2.96Å; S181-G185 PolarHBondContact O-N 3.09Å; S181-S191 WeakPolarHBondContact OG-CB 3.26Å; S181-S191 PolarHBondContact OG-OG 3.11Å; S181-Y195 WeakPolarHBondContact CB-OH 3.5Å; S181-Y195 PolarHBondContact OG-OH 3.45Å
182	M	86.1	Confident	89	Confident	78 Å²	78	51.4 Å²	51.4	38%	0.384	32%	0.316	S	S	.	.	H	α-helix	trans	-63	-39.8	177.4	-69.6	178.9	70.8	0	0	112.7	M178 L179 Q326 F327 P330	M178-M182 HydrophobicContact CG-SD 4.28Å; M178-M182 WeakPolarHBondContact O-CG 3.34Å; M178-M182 PolarHBondContact O-N 3.07Å; L179-M182 PolarHBondContact O-N 3.04Å; M182-Q326 WeakPolarHBondContact CE-O 3.44Å; M182-F327 HydrophobicContact CB-CE1 4.04Å; M182-P330 HydrophobicContact CE-CG 3.98Å; M182-P330 HydrophobicContact SD-CB 4.33Å; M182-P330 HydrophobicContact SD-CG 3.58Å; M182-P330 VanDerWaalsContact SD-CG 3.58Å
183	A	87.2	Confident	88.8	Confident	73 Å²	73	52.2 Å²	52.2	60%	0.603	32%	0.32	S	S	*	.	H	α-helix	trans	-74.4	-33.3	-179.4	0	0	0	0	0	113.2	L179 L180 S181 G185	L179-A183 VanDerWaalsContact O-CB 3.27Å; L179-A183 WeakPolarHBondContact O-CB 3.24Å; L179-A183 PolarHBondContact O-N 3.27Å; L180-A183 PolarHBondContact O-N 3.29Å; S181-A183 PolarHBondContact O-N 3.36Å; A183-G185 VanDerWaalsContact C-N 3.33Å
184	S	85.9	Confident	88.6	Confident	69 Å²	69	49.5 Å²	49.5	48%	0.483	32%	0.318	S	S	.	.	H	α-helix	trans	-75	-19.8	-178.6	63.3	0	0	0	0	113.6	L180 S181 V186	L180-S184 WeakPolarHBondContact O-CB 3.41Å; L180-S184 PolarHBondContact O-N 3.18Å; L180-S184 PolarHBondContact O-OG 2.92Å; S181-S184 PolarHBondContact O-N 3.25Å; S181-S184 PolarHBondContact O-OG 2.96Å; S184-V186 PolarHBondContact O-N 3.08Å; S184-V186 WeakPolarHBondContact OG-CG2 3.46Å
185	G	78.8	Confident	88.5	Confident	70 Å²	70	50.3 Å²	50.3	72%	0.722	32%	0.32	S	S	*	.	T	Hydrogen-bonded Turn	trans	64.5	16.4	-179.3	0	0	0	0	0	113.8	S181 A183	S181-G185 PolarHBondContact O-N 3.09Å; A183-G185 VanDerWaalsContact C-N 3.33Å
186	V	82.6	Confident	88.5	Confident	64 Å²	64	50.2 Å²	50.2	39%	0.388	32%	0.319	S	S	.	.			trans	-68.4	150.1	179.8	174.7	0	0	0	0	109.7	S184 T190	S184-V186 PolarHBondContact O-N 3.08Å; S184-V186 WeakPolarHBondContact OG-CG2 3.46Å; V186-T190 HydrophobicContact CG1-CG2 3.62Å
187	D	84.6	Confident	88.5	Confident	82 Å²	82	51 Å²	51	44%	0.439	32%	0.323	S	S	.	.			trans	-56.3	150	178.1	70	-83.2	0	0	0	112.1	Q189 T190 S191	D187-Q189 PolarHBondContact O-N 3.46Å; D187-Q189 WeakPolarHBondContact OD2-CB 3.38Å; D187-Q189 PolarHBondContact OD2-N 2.7Å; D187-T190 VanDerWaalsContact CG-OG1 3.23Å; D187-T190 PolarHBondContact O-N 3.27Å; D187-T190 WeakPolarHBondContact OD1-CB 3.49Å; D187-T190 PolarHBondContact OD1-OG1 2.97Å; D187-T190 PolarHBondContact OD2-N 3.42Å; D187-T190 PolarHBondContact OD2-OG1 3.1Å; D187-T190 VanDerWaalsContact OD2-OG1 3.06Å; D187-S191 PolarHBondContact O-N 3.23Å; D187-S191 PolarHBondContact O-OG 3.19Å
188	A	82.3	Confident	88.5	Confident	59 Å²	59	53.2 Å²	53.2	49%	0.488	33%	0.334	S	S	.	.	H	α-helix	trans	-61.9	-28.7	-175.1	0	0	0	0	0	112.9	Y38 A192	Y38-A188 HydrophobicContact CD2-CB 4.46Å; Y38-A188 WeakPolarHBondContact CD2-O 3.47Å; A188-A192 VanDerWaalsContact O-CB 3.27Å; A188-A192 WeakPolarHBondContact O-CB 3.34Å; A188-A192 PolarHBondContact O-N 3.34Å
189	Q	85.4	Confident	88.7	Confident	92 Å²	92	51.8 Å²	51.8	43%	0.43	33%	0.327	S	S	.	.	H	α-helix	trans	-72.6	-46.8	179.4	-64.8	-176.9	-18.2	0	0	111.4	Y38 V117 D187 S191 A192 L193	Y38-Q189 HydrophobicContact CE2-CG 4.2Å; V117-Q189 HydrophobicContact CG1-CB 4.31Å; D187-Q189 PolarHBondContact O-N 3.46Å; D187-Q189 WeakPolarHBondContact OD2-CB 3.38Å; D187-Q189 PolarHBondContact OD2-N 2.7Å; Q189-S191 VanDerWaalsContact C-N 3.33Å; Q189-S191 PolarHBondContact O-N 2.99Å; Q189-A192 PolarHBondContact O-N 2.93Å; Q189-L193 WeakPolarHBondContact O-CG 3.42Å; Q189-L193 PolarHBondContact O-N 3.21Å
190	T	88.4	Confident	88.9	Confident	66 Å²	66	51.2 Å²	51.2	41%	0.405	33%	0.326	S	S	.	.	H	α-helix	trans	-64.5	-39.8	177.7	-58.4	0	0	0	0	111.2	V186 D187 L193 G194	V186-T190 HydrophobicContact CG1-CG2 3.62Å; D187-T190 VanDerWaalsContact CG-OG1 3.23Å; D187-T190 PolarHBondContact O-N 3.27Å; D187-T190 WeakPolarHBondContact OD1-CB 3.49Å; D187-T190 PolarHBondContact OD1-OG1 2.97Å; D187-T190 PolarHBondContact OD2-N 3.42Å; D187-T190 PolarHBondContact OD2-OG1 3.1Å; D187-T190 VanDerWaalsContact OD2-OG1 3.06Å; T190-L193 PolarHBondContact O-N 3.49Å; T190-G194 PolarHBondContact O-N 3.29Å; T190-G194 VanDerWaalsContact O-N 3.08Å
191	S	88.8	Confident	89.1	Confident	14 Å²	14	49.1 Å²	49.1	10%	0.098	32%	0.318	C	S	.	.	H	α-helix	trans	-60.8	-45.6	172.5	-64.9	0	0	0	0	111.8	S181 D187 Q189 L193 G194 Y195	S181-S191 WeakPolarHBondContact OG-CB 3.26Å; S181-S191 PolarHBondContact OG-OG 3.11Å; D187-S191 PolarHBondContact O-N 3.23Å; D187-S191 PolarHBondContact O-OG 3.19Å; Q189-S191 VanDerWaalsContact C-N 3.33Å; Q189-S191 PolarHBondContact O-N 2.99Å; S191-L193 VanDerWaalsContact C-N 3.35Å; S191-L193 PolarHBondContact O-N 2.75Å; S191-G194 PolarHBondContact O-N 3.24Å; S191-Y195 WeakPolarHBondContact O-CD2 3.38Å; S191-Y195 VanDerWaalsContact O-CG 3.29Å; S191-Y195 PolarHBondContact O-N 2.88Å
192	A	88.4	Confident	89.4	Confident	0 Å²	0	48 Å²	48	0%	0	31%	0.31	C	S	.	.	H	α-helix	trans	-63.2	-37.5	177.2	0	0	0	0	0	112.9	Y38 V117 A188 Q189 Y195 F196	Y38-A192 HydrophobicContact CD1-CB 3.77Å; Y38-A192 HydrophobicContact CD2-CB 3.51Å; Y38-A192 HydrophobicContact CE1-CB 4.08Å; Y38-A192 HydrophobicContact CE2-CB 3.83Å; Y38-A192 HydrophobicContact CG-CB 3.49Å; Y38-A192 VanDerWaalsContact CG-CB 3.49Å; V117-A192 HydrophobicContact CG1-CB 4.49Å; V117-A192 HydrophobicContact CG2-CB 4.41Å; A188-A192 VanDerWaalsContact O-CB 3.27Å; A188-A192 WeakPolarHBondContact O-CB 3.34Å; A188-A192 PolarHBondContact O-N 3.34Å; Q189-A192 PolarHBondContact O-N 2.93Å; A192-Y195 WeakPolarHBondContact O-CB 3.35Å; A192-Y195 PolarHBondContact O-N 3.29Å; A192-Y195 VanDerWaalsContact O-N 3.12Å; A192-F196 HydrophobicContact CB-CE2 4.09Å; A192-F196 WeakPolarHBondContact O-CD2 3.29Å; A192-F196 PolarHBondContact O-N 3.07Å
193	L	91.4	Very high	89.8	Confident	35 Å²	35	44.3 Å²	44.3	18%	0.183	29%	0.292	C	S	.	.	H	α-helix	trans	-60.8	-45.7	172.9	-72.7	167.7	0	0	0	111.6	A114 V117 K118 Q189 T190 S191 Y195 F196 I197	A114-L193 WeakPolarHBondContact O-CD2 3.42Å; V117-L193 HydrophobicContact CB-CD2 3.73Å; V117-L193 HydrophobicContact CB-CG 4.23Å; V117-L193 HydrophobicContact CG1-CD1 4.4Å; V117-L193 HydrophobicContact CG1-CD2 3.78Å; V117-L193 HydrophobicContact CG1-CG 3.71Å; V117-L193 HydrophobicContact CG2-CD2 4.36Å; K118-L193 HydrophobicContact CD-CD1 4.11Å; K118-L193 HydrophobicContact CG-CD1 4.46Å; K118-L193 HydrophobicContact CG-CD2 4.36Å; Q189-L193 WeakPolarHBondContact O-CG 3.42Å; Q189-L193 PolarHBondContact O-N 3.21Å; T190-L193 PolarHBondContact O-N 3.49Å; S191-L193 VanDerWaalsContact C-N 3.35Å; S191-L193 PolarHBondContact O-N 2.75Å; L193-Y195 PolarHBondContact O-N 3.16Å; L193-F196 PolarHBondContact O-N 3.47Å; L193-I197 WeakPolarHBondContact O-CB 3.36Å; L193-I197 VanDerWaalsContact O-CG1 3.26Å; L193-I197 WeakPolarHBondContact O-CG1 3.45Å; L193-I197 PolarHBondContact O-N 3.43Å
194	G	91.4	Very high	90.3	Very high	34 Å²	34	45 Å²	45	35%	0.351	29%	0.285	S	S	.	.	H	α-helix	trans	-54.1	-44.8	172.2	0	0	0	0	0	111	T190 S191 F196 I197 T198	T190-G194 PolarHBondContact O-N 3.29Å; T190-G194 VanDerWaalsContact O-N 3.08Å; S191-G194 PolarHBondContact O-N 3.24Å; G194-F196 VanDerWaalsContact C-N 3.34Å; G194-F196 PolarHBondContact O-N 3.43Å; G194-I197 PolarHBondContact O-N 2.91Å; G194-T198 WeakPolarHBondContact O-CB 3.45Å; G194-T198 PolarHBondContact O-N 3.36Å; G194-T198 PolarHBondContact O-OG1 3.06Å
195	Y	93.3	Very high	90.8	Very high	22 Å²	22	46.1 Å²	46.1	9%	0.086	28%	0.284	C	S	.	.	H	α-helix	trans	-65.1	-30.8	-179.5	-60	-29.5	0	0	0	115.2	F31 T34 A35 A177 M178 S181 S191 A192 L193 P199	F31-Y195 WeakPolarHBondContact CB-O 3.49Å; F31-Y195 AromaticContact CD1-CD1 3.87Å; F31-Y195 HydrophobicContact CD1-CD1 3.87Å; F31-Y195 HydrophobicContact CD1-CG 4.25Å; F31-Y195 VanDerWaalsContact CD1-O 3.32Å; F31-Y195 WeakPolarHBondContact CD1-O 3.26Å; F31-Y195 HydrophobicContact CE1-CD1 4.02Å; T34-Y195 HydrophobicContact CG2-CE1 4.23Å; T34-Y195 HydrophobicContact CG2-CE2 4.12Å; A35-Y195 HydrophobicContact CB-CD2 3.88Å; A177-Y195 HydrophobicContact CB-CD1 4.2Å; A177-Y195 HydrophobicContact CB-CE1 3.85Å; M178-Y195 WeakPolarHBondContact CA-OH 3.18Å; S181-Y195 WeakPolarHBondContact CB-OH 3.5Å; S181-Y195 PolarHBondContact OG-OH 3.45Å; S191-Y195 WeakPolarHBondContact O-CD2 3.38Å; S191-Y195 VanDerWaalsContact O-CG 3.29Å; S191-Y195 PolarHBondContact O-N 2.88Å; A192-Y195 WeakPolarHBondContact O-CB 3.35Å; A192-Y195 PolarHBondContact O-N 3.29Å; A192-Y195 VanDerWaalsContact O-N 3.12Å; L193-Y195 PolarHBondContact O-N 3.16Å; Y195-P199 WeakPolarHBondContact O-CD 3.32Å; Y195-P199 VanDerWaalsContact O-CG 3.23Å; Y195-P199 WeakPolarHBondContact O-CG 3.2Å
196	F	93.4	Very high	91.6	Very high	0 Å²	0	42.8 Å²	42.8	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-92.5	-26.1	179.2	-58.3	-51.9	0	0	0	113.5	F32 A35 Y38 F39 F110 T113 A114 V117 A192 L193 G194 C200	F32-F196 HydrophobicContact CD2-CE1 4.07Å; A35-F196 HydrophobicContact CB-CE1 3.97Å; A35-F196 HydrophobicContact CB-CE2 4.49Å; A35-F196 HydrophobicContact CB-CZ 3.62Å; Y38-F196 HydrophobicContact CD1-CE2 4.48Å; Y38-F196 HydrophobicContact CE1-CE2 4.4Å; F39-F196 HydrophobicContact CE1-CZ 4.42Å; F39-F196 HydrophobicContact CE2-CE1 4.23Å; F39-F196 AromaticContact CE2-CZ 3.63Å; F39-F196 HydrophobicContact CE2-CZ 3.63Å; F39-F196 HydrophobicContact CZ-CE1 4.09Å; F39-F196 HydrophobicContact CZ-CE2 4.21Å; F39-F196 AromaticContact CZ-CZ 3.4Å; F39-F196 HydrophobicContact CZ-CZ 3.4Å; F39-F196 VanDerWaalsContact CZ-CZ 3.4Å; F110-F196 HydrophobicContact CD1-CD1 4.15Å; F110-F196 HydrophobicContact CE1-CD1 4.1Å; T113-F196 HydrophobicContact CG2-CD1 3.83Å; T113-F196 HydrophobicContact CG2-CD2 3.98Å; T113-F196 HydrophobicContact CG2-CE1 3.72Å; T113-F196 HydrophobicContact CG2-CE2 3.88Å; T113-F196 HydrophobicContact CG2-CG 3.98Å; T113-F196 HydrophobicContact CG2-CZ 3.76Å; A114-F196 HydrophobicContact CB-CB 3.8Å; V117-F196 HydrophobicContact CG2-CD2 3.62Å; V117-F196 HydrophobicContact CG2-CE2 3.64Å; A192-F196 HydrophobicContact CB-CE2 4.09Å; A192-F196 WeakPolarHBondContact O-CD2 3.29Å; A192-F196 PolarHBondContact O-N 3.07Å; L193-F196 PolarHBondContact O-N 3.47Å; G194-F196 VanDerWaalsContact C-N 3.34Å; G194-F196 PolarHBondContact O-N 3.43Å; F196-C200 PolarHBondContact O-SG 2.96Å
197	I	93.8	Very high	92.3	Very high	89 Å²	89	40.2 Å²	40.2	46%	0.456	23%	0.233	S	C	.	.	H	α-helix	trans	-78.8	-38.3	177.1	-64.7	-62.8	0	0	0	111.9	A114 L193 G194 C200 V201	A114-I197 HydrophobicContact CB-CD1 3.95Å; A114-I197 HydrophobicContact CB-CG1 4.49Å; L193-I197 WeakPolarHBondContact O-CB 3.36Å; L193-I197 VanDerWaalsContact O-CG1 3.26Å; L193-I197 WeakPolarHBondContact O-CG1 3.45Å; L193-I197 PolarHBondContact O-N 3.43Å; G194-I197 PolarHBondContact O-N 2.91Å; I197-C200 VanDerWaalsContact O-CB 3.32Å; I197-C200 WeakPolarHBondContact O-CB 3.43Å; I197-C200 PolarHBondContact O-N 3.26Å; I197-C200 VanDerWaalsContact O-N 3.08Å; I197-V201 PolarHBondContact O-N 3.26Å
198	T	93.6	Very high	92.8	Very high	66 Å²	66	41.8 Å²	41.8	41%	0.405	24%	0.239	S	C	.	.	H	α-helix	trans	-57.9	-46.3	-179.9	-65.1	0	0	0	0	112.8	F31 G194 C200 V201 G202	F31-T198 HydrophobicContact CE1-CG2 4.07Å; F31-T198 HydrophobicContact CZ-CG2 3.87Å; G194-T198 WeakPolarHBondContact O-CB 3.45Å; G194-T198 PolarHBondContact O-N 3.36Å; G194-T198 PolarHBondContact O-OG1 3.06Å; T198-C200 VanDerWaalsContact C-N 3.32Å; T198-C200 PolarHBondContact O-N 2.99Å; T198-V201 PolarHBondContact O-N 3.21Å; T198-G202 PolarHBondContact O-N 3.38Å; T198-G202 VanDerWaalsContact O-N 3.14Å
199	P	94.4	Very high	93.4	Very high	0 Å²	0	39.9 Å²	39.9	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-61.2	-34.3	173	-26.6	36.2	0	0	0	114.5	P28 F31 F110 Y195 V201 G202 I203	P28-P199 HydrophobicContact CB-CB 3.96Å; P28-P199 HydrophobicContact CG-CB 4.06Å; F31-P199 HydrophobicContact CB-CG 3.62Å; F31-P199 HydrophobicContact CD1-CG 4.29Å; F31-P199 HydrophobicContact CD2-CG 4.23Å; F31-P199 HydrophobicContact CG-CG 3.78Å; F110-P199 HydrophobicContact CD1-CB 4.12Å; F110-P199 HydrophobicContact CD1-CG 4.35Å; F110-P199 HydrophobicContact CE1-CB 4.31Å; F110-P199 HydrophobicContact CE1-CG 4.28Å; Y195-P199 WeakPolarHBondContact O-CD 3.32Å; Y195-P199 VanDerWaalsContact O-CG 3.23Å; Y195-P199 WeakPolarHBondContact O-CG 3.2Å; P199-V201 VanDerWaalsContact C-N 3.28Å; P199-V201 PolarHBondContact O-N 3.38Å; P199-G202 CarbonylContact O-C 3.57Å; P199-G202 WeakPolarHBondContact O-CA 3.31Å; P199-G202 PolarHBondContact O-N 3.27Å; P199-G202 VanDerWaalsContact O-N 3.12Å; P199-I203 VanDerWaalsContact O-CG1 3.26Å; P199-I203 WeakPolarHBondContact O-CG1 3.35Å; P199-I203 PolarHBondContact O-N 3.07Å
200	C	95.9	Very high	93.7	Very high	14 Å²	14	36.3 Å²	36.3	10%	0.095	21%	0.205	C	C	.	.	H	α-helix	trans	-58.8	-42	175.3	-66.8	0	0	0	0	111.5	L107 F196 I197 T198 I203 L204	L107-C200 HydrophobicContact CD1-CB 3.65Å; F196-C200 PolarHBondContact O-SG 2.96Å; I197-C200 VanDerWaalsContact O-CB 3.32Å; I197-C200 WeakPolarHBondContact O-CB 3.43Å; I197-C200 PolarHBondContact O-N 3.26Å; I197-C200 VanDerWaalsContact O-N 3.08Å; T198-C200 VanDerWaalsContact C-N 3.32Å; T198-C200 PolarHBondContact O-N 2.99Å; C200-I203 PolarHBondContact O-N 3.37Å; C200-L204 VanDerWaalsContact O-CG 3.31Å; C200-L204 WeakPolarHBondContact O-CG 3.15Å; C200-L204 PolarHBondContact O-N 3.46Å
201	V	95.7	Very high	94	Very high	78 Å²	78	37 Å²	37	47%	0.473	21%	0.206	S	C	.	.	H	α-helix	trans	-63.9	-44.3	174.3	-178	0	0	0	0	110.8	I197 T198 P199 I203 L204 M205	I197-V201 PolarHBondContact O-N 3.26Å; T198-V201 PolarHBondContact O-N 3.21Å; P199-V201 VanDerWaalsContact C-N 3.28Å; P199-V201 PolarHBondContact O-N 3.38Å; V201-I203 PolarHBondContact O-N 3.19Å; V201-L204 PolarHBondContact O-N 3.29Å; V201-M205 HydrophobicContact CG1-CE 4.2Å; V201-M205 WeakPolarHBondContact O-CG 3.35Å; V201-M205 PolarHBondContact O-N 3.22Å
202	G	95.3	Very high	94	Very high	2 Å²	2	38.4 Å²	38.4	2%	0.021	22%	0.216	C	C	.	.	H	α-helix	trans	-58.3	-42.9	175.5	0	0	0	0	0	113.6	T198 P199 M205 S206	T198-G202 PolarHBondContact O-N 3.38Å; T198-G202 VanDerWaalsContact O-N 3.14Å; P199-G202 CarbonylContact O-C 3.57Å; P199-G202 WeakPolarHBondContact O-CA 3.31Å; P199-G202 PolarHBondContact O-N 3.27Å; P199-G202 VanDerWaalsContact O-N 3.12Å; G202-M205 PolarHBondContact O-N 2.97Å; G202-S206 WeakPolarHBondContact O-CB 3.39Å; G202-S206 PolarHBondContact O-N 3.37Å; G202-S206 PolarHBondContact O-OG 3.47Å
203	I	96.3	Very high	94	Very high	1 Å²	1	38.5 Å²	38.5	1%	0.005	22%	0.216	C	C	.	.	H	α-helix	trans	-67.5	-43.6	177.4	-64.9	161	0	0	0	110.6	P28 L103 I106 L107 P199 C200 V201 M205 S206 I207	P28-I203 HydrophobicContact CB-CD1 4.41Å; P28-I203 HydrophobicContact CG-CD1 3.7Å; P28-I203 HydrophobicContact CG-CG1 3.89Å; L103-I203 HydrophobicContact CB-CG2 4.24Å; L103-I203 HydrophobicContact CD2-CG2 4.13Å; L103-I203 WeakPolarHBondContact O-CG2 3.47Å; I106-I203 HydrophobicContact CB-CD1 4.43Å; I106-I203 HydrophobicContact CG2-CD1 3.71Å; L107-I203 HydrophobicContact CB-CD1 4.49Å; L107-I203 HydrophobicContact CB-CG2 3.92Å; L107-I203 HydrophobicContact CD1-CB 4.41Å; L107-I203 HydrophobicContact CD1-CG2 4.47Å; P199-I203 VanDerWaalsContact O-CG1 3.26Å; P199-I203 WeakPolarHBondContact O-CG1 3.35Å; P199-I203 PolarHBondContact O-N 3.07Å; C200-I203 PolarHBondContact O-N 3.37Å; V201-I203 PolarHBondContact O-N 3.19Å; I203-M205 VanDerWaalsContact C-N 3.34Å; I203-M205 PolarHBondContact O-N 2.73Å; I203-S206 CarbonylContact O-C 3.45Å; I203-S206 WeakPolarHBondContact O-CA 3.14Å; I203-S206 WeakPolarHBondContact O-CB 3.22Å; I203-S206 PolarHBondContact O-N 3.46Å; I203-S206 VanDerWaalsContact O-N 3.08Å; I203-I207 HydrophobicContact CG2-CD1 3.96Å; I203-I207 HydrophobicContact CG2-CG1 4.36Å; I203-I207 WeakPolarHBondContact O-CG1 3.45Å; I203-I207 PolarHBondContact O-N 2.95Å
204	L	97	Very high	93.7	Very high	88 Å²	88	40.9 Å²	40.9	46%	0.461	23%	0.234	S	C	.	.	H	α-helix	trans	-59.5	-44.2	176.2	-74.7	170.5	0	0	0	111.7	L107 C200 V201 S206 I207 M208	L107-L204 HydrophobicContact CD1-CG 4.33Å; L107-L204 HydrophobicContact CD2-CD2 3.7Å; L107-L204 HydrophobicContact CD2-CG 4.18Å; C200-L204 VanDerWaalsContact O-CG 3.31Å; C200-L204 WeakPolarHBondContact O-CG 3.15Å; C200-L204 PolarHBondContact O-N 3.46Å; V201-L204 PolarHBondContact O-N 3.29Å; L204-S206 VanDerWaalsContact C-N 3.29Å; L204-S206 PolarHBondContact O-N 2.95Å; L204-I207 PolarHBondContact O-N 3.04Å; L204-M208 WeakPolarHBondContact O-CG 3.15Å; L204-M208 PolarHBondContact O-N 3.3Å
205	M	96.1	Very high	93.4	Very high	92 Å²	92	47.1 Å²	47.1	45%	0.453	25%	0.254	S	S	.	.	H	α-helix	trans	-60.6	-40	173.4	-70.4	-172.7	-63.4	0	0	111.8	I20 V201 G202 I203 M208 C209	I20-M205 HydrophobicContact CG2-CB 4.25Å; V201-M205 HydrophobicContact CG1-CE 4.2Å; V201-M205 WeakPolarHBondContact O-CG 3.35Å; V201-M205 PolarHBondContact O-N 3.22Å; G202-M205 PolarHBondContact O-N 2.97Å; I203-M205 VanDerWaalsContact C-N 3.34Å; I203-M205 PolarHBondContact O-N 2.73Å; M205-M208 PolarHBondContact O-N 3.4Å; M205-C209 PolarHBondContact O-N 2.91Å; M205-C209 PolarHBondContact O-SG 2.82Å
206	S	96.2	Very high	93	Very high	0 Å²	0	48 Å²	48	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-65.2	-40.2	177.3	-58.1	0	0	0	0	112.3	I20 G24 G202 I203 L204 C209 Y210	I20-S206 PolarHBondContact O-OG 3.17Å; G24-S206 WeakPolarHBondContact CA-OG 3.16Å; G202-S206 WeakPolarHBondContact O-CB 3.39Å; G202-S206 PolarHBondContact O-N 3.37Å; G202-S206 PolarHBondContact O-OG 3.47Å; I203-S206 CarbonylContact O-C 3.45Å; I203-S206 WeakPolarHBondContact O-CA 3.14Å; I203-S206 WeakPolarHBondContact O-CB 3.22Å; I203-S206 PolarHBondContact O-N 3.46Å; I203-S206 VanDerWaalsContact O-N 3.08Å; L204-S206 VanDerWaalsContact C-N 3.29Å; L204-S206 PolarHBondContact O-N 2.95Å; S206-C209 PolarHBondContact O-N 3.35Å; S206-Y210 PolarHBondContact O-N 3.26Å
207	I	96.4	Very high	92.5	Very high	10 Å²	10	56.6 Å²	56.6	5%	0.051	30%	0.297	C	S	.	.	H	α-helix	trans	-61.5	-47.6	174.4	-69	167	0	0	0	110.3	L100 L103 L104 L107 I203 L204 C209 Y210 L211	L100-I207 HydrophobicContact CD1-CB 4.36Å; L100-I207 HydrophobicContact CD1-CG1 4.13Å; L100-I207 HydrophobicContact CD1-CG2 3.56Å; L103-I207 HydrophobicContact CB-CD1 4.11Å; L103-I207 HydrophobicContact CB-CG1 3.73Å; L103-I207 HydrophobicContact CD1-CG1 3.93Å; L103-I207 HydrophobicContact CG-CG1 4.38Å; L104-I207 HydrophobicContact CD2-CD1 3.93Å; L104-I207 HydrophobicContact CG-CD1 4.38Å; L107-I207 HydrophobicContact CD2-CD1 4.41Å; I203-I207 HydrophobicContact CG2-CD1 3.96Å; I203-I207 HydrophobicContact CG2-CG1 4.36Å; I203-I207 WeakPolarHBondContact O-CG1 3.45Å; I203-I207 PolarHBondContact O-N 2.95Å; L204-I207 PolarHBondContact O-N 3.04Å; I207-C209 VanDerWaalsContact C-N 3.32Å; I207-C209 PolarHBondContact O-N 2.67Å; I207-Y210 PolarHBondContact O-N 3.39Å; I207-L211 HydrophobicContact CG2-CD1 4.01Å; I207-L211 HydrophobicContact CG2-CG 4.41Å; I207-L211 WeakPolarHBondContact O-CG 3.49Å; I207-L211 PolarHBondContact O-N 3.44Å
208	M	95.4	Very high	92	Very high	115 Å²	115	53.2 Å²	53.2	57%	0.567	28%	0.279	S	S	*	.	H	α-helix	trans	-60.3	-42.5	176.9	-66.3	-61.9	98.9	0	0	111.8	L204 M205 L211 S212	L204-M208 WeakPolarHBondContact O-CG 3.15Å; L204-M208 PolarHBondContact O-N 3.3Å; M205-M208 PolarHBondContact O-N 3.4Å; M208-L211 HydrophobicContact CE-CD1 3.94Å; M208-L211 PolarHBondContact O-N 3.43Å; M208-S212 PolarHBondContact O-N 2.8Å; M208-S212 VanDerWaalsContact O-N 3.07Å
209	C	94.5	Very high	91.3	Very high	19 Å²	19	50 Å²	50	13%	0.128	26%	0.259	C	S	.	.	H	α-helix	trans	-61	-47	175.8	-70.2	0	0	0	0	111.5	M205 S206 I207 L211 S212 L213	M205-C209 PolarHBondContact O-N 2.91Å; M205-C209 PolarHBondContact O-SG 2.82Å; S206-C209 PolarHBondContact O-N 3.35Å; I207-C209 VanDerWaalsContact C-N 3.32Å; I207-C209 PolarHBondContact O-N 2.67Å; C209-L211 PolarHBondContact O-N 2.65Å; C209-S212 PolarHBondContact O-N 3.18Å; C209-S212 VanDerWaalsContact O-N 3.16Å; C209-S212 PolarHBondContact O-OG 2.97Å; C209-L213 PolarHBondContact O-N 3.39Å
210	Y	93.3	Very high	90.7	Very high	17 Å²	17	58.3 Å²	58.3	7%	0.067	29%	0.291	C	S	.	.	H	α-helix	trans	-61.6	-44.1	178.7	-171.5	-105.8	0	0	0	112.4	L21 T96 I99 S206 I207 S212 L213 P214	L21-Y210 HydrophobicContact CD1-CD2 4.29Å; T96-Y210 WeakPolarHBondContact CA-OH 3.43Å; T96-Y210 HydrophobicContact CG2-CE1 4.38Å; I99-Y210 HydrophobicContact CB-CE1 4.21Å; I99-Y210 HydrophobicContact CB-CE2 4.12Å; I99-Y210 HydrophobicContact CD1-CE2 3.57Å; I99-Y210 HydrophobicContact CG1-CE2 4.43Å; I99-Y210 HydrophobicContact CG2-CD1 4.14Å; I99-Y210 HydrophobicContact CG2-CD2 3.76Å; I99-Y210 HydrophobicContact CG2-CE1 4.05Å; I99-Y210 HydrophobicContact CG2-CE2 3.68Å; I99-Y210 HydrophobicContact CG2-CG 4.01Å; S206-Y210 PolarHBondContact O-N 3.26Å; I207-Y210 PolarHBondContact O-N 3.39Å; Y210-S212 PolarHBondContact O-N 2.82Å; Y210-L213 HydrophobicContact CD2-CD1 3.96Å; Y210-L213 HydrophobicContact CE2-CD1 4.42Å; Y210-L213 WeakPolarHBondContact O-CB 3.46Å; Y210-L213 PolarHBondContact O-N 3.18Å; Y210-P214 WeakPolarHBondContact O-CD 3.28Å
211	L	92.8	Very high	89.9	Confident	81 Å²	81	62.2 Å²	62.2	42%	0.424	30%	0.304	S	S	.	.	H	α-helix	trans	-65.7	-24.1	177.5	-68.3	177.5	0	0	0	113	L100 I207 M208 C209 P214	L100-L211 HydrophobicContact CD2-CD2 4.11Å; I207-L211 HydrophobicContact CG2-CD1 4.01Å; I207-L211 HydrophobicContact CG2-CG 4.41Å; I207-L211 WeakPolarHBondContact O-CG 3.49Å; I207-L211 PolarHBondContact O-N 3.44Å; M208-L211 HydrophobicContact CE-CD1 3.94Å; M208-L211 PolarHBondContact O-N 3.43Å; C209-L211 PolarHBondContact O-N 2.65Å; L211-P214 WeakPolarHBondContact O-CD 3.47Å
212	S	90.4	Very high	89	Confident	44 Å²	44	61.4 Å²	61.4	31%	0.308	29%	0.293	S	S	.	.	H	α-helix	trans	-77.8	-24.4	176	78.8	0	0	0	0	113.6	M208 C209 Y210 H215	M208-S212 PolarHBondContact O-N 2.8Å; M208-S212 VanDerWaalsContact O-N 3.07Å; C209-S212 PolarHBondContact O-N 3.18Å; C209-S212 VanDerWaalsContact O-N 3.16Å; C209-S212 PolarHBondContact O-OG 2.97Å; Y210-S212 PolarHBondContact O-N 2.82Å; S212-H215 WeakPolarHBondContact O-CB 3.24Å; S212-H215 PolarHBondContact O-N 2.86Å; S212-H215 VanDerWaalsContact O-N 3.08Å
213	L	88.4	Confident	88	Confident	2 Å²	2	63.6 Å²	63.6	1%	0.01	30%	0.304	C	S	.	.	G	3₁₀ helix	trans	-56.2	-45.3	-175.2	-71.8	174.5	0	0	0	113.7	V14 F18 L21 C209 Y210 H215 L216 A219	V14-L213 HydrophobicContact CG1-CD2 4.23Å; F18-L213 HydrophobicContact CE2-CD1 4.44Å; F18-L213 HydrophobicContact CE2-CD2 4.32Å; F18-L213 HydrophobicContact CZ-CD1 4.14Å; L21-L213 HydrophobicContact CD1-CD1 4.09Å; C209-L213 PolarHBondContact O-N 3.39Å; Y210-L213 HydrophobicContact CD2-CD1 3.96Å; Y210-L213 HydrophobicContact CE2-CD1 4.42Å; Y210-L213 WeakPolarHBondContact O-CB 3.46Å; Y210-L213 PolarHBondContact O-N 3.18Å; L213-H215 PolarHBondContact O-N 2.97Å; L213-H215 VanDerWaalsContact O-N 3.13Å; L213-L216 HydrophobicContact CD2-CD1 4.45Å; L213-L216 PolarHBondContact O-N 3.13Å; L213-A219 HydrophobicContact CB-CB 4.37Å; L213-A219 HydrophobicContact CD2-CB 4.29Å; L213-A219 WeakPolarHBondContact O-CB 3.43Å
214	P	85	Confident	86.5	Confident	85 Å²	85	66.6 Å²	66.6	55%	0.552	33%	0.329	S	S	*	.	G	3₁₀ helix	trans	-61.7	-22.4	179.2	-24	35.4	0	0	0	114.4	Y210 L211 L216	Y210-P214 WeakPolarHBondContact O-CD 3.28Å; L211-P214 WeakPolarHBondContact O-CD 3.47Å; P214-L216 VanDerWaalsContact C-N 3.33Å
215	H	85	Confident	84.3	Confident	165 Å²	165	66.3 Å²	66.3	76%	0.764	33%	0.328	S	S	*	.	G	3₁₀ helix	trans	-80.9	-14.3	177.8	-64.7	-73.9	0	0	0	112.9	S212 L213	S212-H215 WeakPolarHBondContact O-CB 3.24Å; S212-H215 PolarHBondContact O-N 2.86Å; S212-H215 VanDerWaalsContact O-N 3.08Å; L213-H215 PolarHBondContact O-N 2.97Å; L213-H215 VanDerWaalsContact O-N 3.13Å
216	L	85.3	Confident	82	Confident	39 Å²	39	69.4 Å²	69.4	20%	0.204	34%	0.339	C	S	.	.	S	Bend	trans	-88.6	124.1	179.7	-60.5	175.4	0	0	0	110.6	L13 V14 L213 P214 F218 A219 R220	L13-L216 HydrophobicContact CB-CD1 4.03Å; L13-L216 HydrophobicContact CB-CD2 4.36Å; L13-L216 HydrophobicContact CD1-CD2 4.06Å; V14-L216 HydrophobicContact CG2-CB 4.1Å; V14-L216 HydrophobicContact CG2-CD1 3.62Å; V14-L216 HydrophobicContact CG2-CG 4.5Å; L213-L216 HydrophobicContact CD2-CD1 4.45Å; L213-L216 PolarHBondContact O-N 3.13Å; P214-L216 VanDerWaalsContact C-N 3.33Å; L216-F218 PolarHBondContact O-N 3.06Å; L216-A219 HydrophobicContact CB-CB 4.2Å; L216-A219 PolarHBondContact O-N 3.44Å; L216-R220 PolarHBondContact O-N 2.87Å
217	K	82.2	Confident	79.4	Confident	181 Å²	181	72.6 Å²	72.6	79%	0.787	36%	0.359	S	S	*	.	H	α-helix	trans	-56.1	-37.4	-178.2	-64.6	-179	-177.8	177.7	0	112.9	Y221	K217-Y221 PolarHBondContact O-N 3.3Å; K217-Y221 VanDerWaalsContact O-N 3.08Å
218	F	82.8	Confident	76.5	Confident	18 Å²	18	76.4 Å²	76.4	8%	0.079	39%	0.387	C	S	.	.	H	α-helix	trans	-64.5	-53.8	177.8	-175.8	-83.2	0	0	0	112.1	P7 D9 V14 Y159 L216 R220 Y221 Y222	P7-F218 HydrophobicContact CG-CD2 4.48Å; P7-F218 WeakPolarHBondContact O-CD2 3.44Å; P7-F218 WeakPolarHBondContact O-CE2 3.44Å; D9-F218 HydrophobicContact CB-CD2 3.91Å; D9-F218 HydrophobicContact CB-CE2 4.22Å; D9-F218 HydrophobicContact CB-CG 4.09Å; V14-F218 HydrophobicContact CB-CD1 4.21Å; V14-F218 HydrophobicContact CG1-CD1 4.11Å; V14-F218 HydrophobicContact CG2-CB 4.05Å; V14-F218 HydrophobicContact CG2-CD1 3.95Å; V14-F218 HydrophobicContact CG2-CG 4.34Å; Y159-F218 HydrophobicContact CD2-CE1 4.45Å; Y159-F218 HydrophobicContact CE1-CE1 4.31Å; Y159-F218 AromaticContact CE2-CE1 3.53Å; Y159-F218 HydrophobicContact CE2-CE1 3.53Å; Y159-F218 AromaticContact CE2-CZ 3.57Å; Y159-F218 HydrophobicContact CE2-CZ 3.57Å; Y159-F218 AromaticContact CZ-CE1 3.45Å; Y159-F218 VanDerWaalsContact CZ-CE1 3.45Å; Y159-F218 AromaticContact CZ-CZ 3.69Å; Y159-F218 VanDerWaalsContact OH-CE1 3.28Å; Y159-F218 WeakPolarHBondContact OH-CE1 3.35Å; Y159-F218 VanDerWaalsContact OH-CZ 3.26Å; Y159-F218 WeakPolarHBondContact OH-CZ 3.43Å; L216-F218 PolarHBondContact O-N 3.06Å; F218-R220 VanDerWaalsContact C-N 3.28Å; F218-R220 PolarHBondContact O-N 2.97Å; F218-Y221 WeakPolarHBondContact O-CB 3.33Å; F218-Y221 PolarHBondContact O-N 3.42Å; F218-Y221 VanDerWaalsContact O-N 3.07Å; F218-Y222 HydrophobicContact CD1-CD2 4.01Å; F218-Y222 HydrophobicContact CD1-CE2 4.37Å; F218-Y222 HydrophobicContact CD2-CE2 4.29Å; F218-Y222 AromaticContact CE1-CD2 3.54Å; F218-Y222 HydrophobicContact CE1-CD2 3.54Å; F218-Y222 AromaticContact CE1-CE2 3.69Å; F218-Y222 HydrophobicContact CE1-CE2 3.69Å; F218-Y222 HydrophobicContact CE2-CD2 4.19Å; F218-Y222 AromaticContact CE2-CE2 3.59Å; F218-Y222 HydrophobicContact CE2-CE2 3.59Å; F218-Y222 AromaticContact CZ-CD2 3.64Å; F218-Y222 HydrophobicContact CZ-CD2 3.64Å; F218-Y222 AromaticContact CZ-CE2 3.23Å; F218-Y222 HydrophobicContact CZ-CE2 3.23Å; F218-Y222 PolarHBondContact O-N 2.53Å
219	A	79.3	Confident	73.8	Confident	0 Å²	0	78.1 Å²	78.1	0%	0	39%	0.394	C	S	.	.	H	α-helix	trans	-60.7	-41.2	179.2	0	0	0	0	0	110.5	V14 L213 L216 Y221 Y222 L223	V14-A219 HydrophobicContact CG1-CB 4.47Å; V14-A219 HydrophobicContact CG2-CB 4.06Å; L213-A219 HydrophobicContact CB-CB 4.37Å; L213-A219 HydrophobicContact CD2-CB 4.29Å; L213-A219 WeakPolarHBondContact O-CB 3.43Å; L216-A219 HydrophobicContact CB-CB 4.2Å; L216-A219 PolarHBondContact O-N 3.44Å; A219-Y221 VanDerWaalsContact C-N 3.3Å; A219-Y221 PolarHBondContact O-N 3.44Å; A219-Y222 PolarHBondContact O-N 3.25Å; A219-L223 HydrophobicContact CB-CD1 4.08Å; A219-L223 WeakPolarHBondContact O-CB 3.46Å; A219-L223 WeakPolarHBondContact O-CG 3.17Å; A219-L223 PolarHBondContact O-N 3.01Å
220	R	81.3	Confident	71	Confident	173 Å²	173	80.4 Å²	80.4	65%	0.653	41%	0.414	S	S	*	.	H	α-helix	trans	-59.7	-38.2	174.6	-169.3	175.5	178.6	177.1	-0.2	112.8	L216 F218 A224	L216-R220 PolarHBondContact O-N 2.87Å; F218-R220 VanDerWaalsContact C-N 3.28Å; F218-R220 PolarHBondContact O-N 2.97Å; R220-A224 HydrophobicContact CG-CB 3.84Å; R220-A224 WeakPolarHBondContact O-CA 3.36Å; R220-A224 WeakPolarHBondContact O-CB 3.5Å; R220-A224 PolarHBondContact O-N 3.06Å
221	Y	78.9	Confident	68.5	Low	96 Å²	96	85.2 Å²	85.2	38%	0.376	44%	0.437	S	S	.	.	H	α-helix	trans	-63.9	-42.9	178.4	177.5	-92.8	0	0	0	112.7	A6 P7 K217 F218 A219 N225	A6-Y221 HydrophobicContact CB-CE1 4.12Å; P7-Y221 HydrophobicContact CG-CD1 4.27Å; P7-Y221 HydrophobicContact CG-CD2 4.28Å; P7-Y221 HydrophobicContact CG-CG 3.81Å; K217-Y221 PolarHBondContact O-N 3.3Å; K217-Y221 VanDerWaalsContact O-N 3.08Å; F218-Y221 WeakPolarHBondContact O-CB 3.33Å; F218-Y221 PolarHBondContact O-N 3.42Å; F218-Y221 VanDerWaalsContact O-N 3.07Å; A219-Y221 VanDerWaalsContact C-N 3.3Å; A219-Y221 PolarHBondContact O-N 3.44Å; Y221-N225 VanDerWaalsContact O-CB 3.29Å; Y221-N225 WeakPolarHBondContact O-CB 3.14Å; Y221-N225 PolarHBondContact O-ND2 2.76Å
222	Y	76.9	Confident	66.1	Low	62 Å²	62	82.9 Å²	82.9	24%	0.243	43%	0.43	C	S	.	.	H	α-helix	trans	-83.7	-31.5	179.8	-75.1	-82.1	0	0	0	113.6	P156 F218 A219	P156-Y222 HydrophobicContact CG-CE1 4.21Å; F218-Y222 HydrophobicContact CD1-CD2 4.01Å; F218-Y222 HydrophobicContact CD1-CE2 4.37Å; F218-Y222 HydrophobicContact CD2-CE2 4.29Å; F218-Y222 AromaticContact CE1-CD2 3.54Å; F218-Y222 HydrophobicContact CE1-CD2 3.54Å; F218-Y222 AromaticContact CE1-CE2 3.69Å; F218-Y222 HydrophobicContact CE1-CE2 3.69Å; F218-Y222 HydrophobicContact CE2-CD2 4.19Å; F218-Y222 AromaticContact CE2-CE2 3.59Å; F218-Y222 HydrophobicContact CE2-CE2 3.59Å; F218-Y222 AromaticContact CZ-CD2 3.64Å; F218-Y222 HydrophobicContact CZ-CD2 3.64Å; F218-Y222 AromaticContact CZ-CE2 3.23Å; F218-Y222 HydrophobicContact CZ-CE2 3.23Å; F218-Y222 PolarHBondContact O-N 2.53Å; A219-Y222 PolarHBondContact O-N 3.25Å
223	L	75.3	Confident	63.9	Low	47 Å²	47	86.5 Å²	86.5	25%	0.246	44%	0.441	C	S	.	.	H	α-helix	trans	-92.6	-34.3	-175.5	-62.7	175.6	0	0	0	114.2	Q151 M155 A219	Q151-L223 HydrophobicContact CG-CD2 3.31Å; M155-L223 HydrophobicContact CE-CD1 3.81Å; M155-L223 HydrophobicContact CE-CD2 3.48Å; M155-L223 VanDerWaalsContact CE-CD2 3.48Å; M155-L223 HydrophobicContact CE-CG 3.47Å; M155-L223 VanDerWaalsContact CE-CG 3.47Å; A219-L223 HydrophobicContact CB-CD1 4.08Å; A219-L223 WeakPolarHBondContact O-CB 3.46Å; A219-L223 WeakPolarHBondContact O-CG 3.17Å; A219-L223 PolarHBondContact O-N 3.01Å
224	A	63.8	Low	62.1	Low	64 Å²	64	91.5 Å²	91.5	53%	0.529	47%	0.465	S	S	.	.	H	α-helix	trans	-87.4	-25.5	-178.7	0	0	0	0	0	112.4	R220 K226	R220-A224 HydrophobicContact CG-CB 3.84Å; R220-A224 WeakPolarHBondContact O-CA 3.36Å; R220-A224 WeakPolarHBondContact O-CB 3.5Å; R220-A224 PolarHBondContact O-N 3.06Å; A224-K226 PolarHBondContact O-N 3.4Å; A224-K226 VanDerWaalsContact O-N 3.09Å
225	N	50.4	Low	60.4	Low	83 Å²	83	93.2 Å²	93.2	44%	0.444	47%	0.469	S	S	.	.			trans	-83.6	69.1	168.4	-64.5	-28.7	0	0	0	109.4	Y221 P227	Y221-N225 VanDerWaalsContact O-CB 3.29Å; Y221-N225 WeakPolarHBondContact O-CB 3.14Å; Y221-N225 PolarHBondContact O-ND2 2.76Å; N225-P227 WeakPolarHBondContact O-CD 3.4Å; N225-P227 VanDerWaalsContact O-N 3.08Å
226	K	49.2	Very low	59	Low	157 Å²	157	89.6 Å²	89.6	68%	0.683	45%	0.452	S	S	*	.	P	Polyproline II helix	trans	-54.4	116	143.8	-79	-174.4	174.9	-174.2	0	104	A224 S228	A224-K226 PolarHBondContact O-N 3.4Å; A224-K226 VanDerWaalsContact O-N 3.09Å; K226-S228 PolarHBondContact O-N 3.23Å
227	P	41	Very low	57.5	Low	66 Å²	66	91.3 Å²	91.3	43%	0.429	46%	0.464	S	S	.	.	P	Polyproline II helix	trans	-53.4	117.1	-171.6	19.7	-29.9	0	0	0	107	N225 Q229	N225-P227 WeakPolarHBondContact O-CD 3.4Å; N225-P227 VanDerWaalsContact O-N 3.08Å; P227-Q229 PolarHBondContact O-N 3.1Å; P227-Q229 VanDerWaalsContact O-N 3.17Å
228	S	36.5	Very low	56.3	Low	91 Å²	91	87 Å²	87	64%	0.636	45%	0.446	S	S	*	.	P	Polyproline II helix	trans	-49.4	128.9	164.6	-87.1	0	0	0	0	105.5	K226 A230 Q231	K226-S228 PolarHBondContact O-N 3.23Å; S228-A230 PolarHBondContact O-N 3.15Å; S228-Q231 PolarHBondContact O-N 3.13Å
229	Q	38.6	Very low	55.1	Low	151 Å²	151	88.5 Å²	88.5	71%	0.706	46%	0.461	S	S	*	.	H	α-helix	trans	-41.2	-31.2	-177.2	-83.9	169	-51.6	0	0	113.7	P227 Q231 A232 Q233	P227-Q229 PolarHBondContact O-N 3.1Å; P227-Q229 VanDerWaalsContact O-N 3.17Å; Q229-Q231 PolarHBondContact O-N 2.94Å; Q229-A232 PolarHBondContact O-N 3.24Å; Q229-Q233 PolarHBondContact O-N 2.74Å; Q229-Q233 VanDerWaalsContact O-N 3.14Å
230	A	35.6	Very low	54.1	Low	67 Å²	67	94.7 Å²	94.7	55%	0.554	49%	0.49	S	S	*	.	H	α-helix	trans	-59.1	-34.4	174.2	0	0	0	0	0	115.6	S228 E234	S228-A230 PolarHBondContact O-N 3.15Å; A230-E234 PolarHBondContact O-N 3.37Å; A230-E234 VanDerWaalsContact O-N 3.17Å
231	Q	39.1	Very low	52.8	Low	117 Å²	117	91.2 Å²	91.2	55%	0.547	48%	0.484	S	S	.	.	H	α-helix	trans	-85.5	-25.9	-175.8	-138	173.9	6.9	0	0	112.6	S228 Q229 L235	S228-Q231 PolarHBondContact O-N 3.13Å; Q229-Q231 PolarHBondContact O-N 2.94Å; Q231-L235 PolarHBondContact O-N 2.98Å
232	A	44	Very low	51.6	Low	33 Å²	33	92.6 Å²	92.6	27%	0.273	50%	0.497	S	S	.	.	H	α-helix	trans	-72.4	-42.8	169.1	0	0	0	0	0	110.6	Q229 E234 L235 E236	Q229-A232 PolarHBondContact O-N 3.24Å; A232-E234 VanDerWaalsContact C-N 3.35Å; A232-E234 PolarHBondContact O-N 2.9Å; A232-L235 PolarHBondContact O-N 3.39Å; A232-E236 PolarHBondContact O-N 2.87Å
233	Q	43.5	Very low	50.3	Low	119 Å²	119	96.3 Å²	96.3	56%	0.556	52%	0.517	S	S	*	.	H	α-helix	trans	-56.4	-44.9	172	-91.1	175.7	-57	0	0	112.2	Q229 L235 E236 T237	Q229-Q233 PolarHBondContact O-N 2.74Å; Q229-Q233 VanDerWaalsContact O-N 3.14Å; Q233-L235 VanDerWaalsContact C-N 3.27Å; Q233-L235 PolarHBondContact O-N 2.98Å; Q233-E236 PolarHBondContact O-N 2.7Å; Q233-T237 WeakPolarHBondContact O-CB 3.26Å; Q233-T237 PolarHBondContact O-N 3.35Å; Q233-T237 PolarHBondContact O-OG1 3.09Å
234	E	49.8	Very low	49	Very low	107 Å²	107	97.3 Å²	97.3	50%	0.5	53%	0.528	S	S	.	.	H	α-helix	trans	-65.6	-30.6	-179.5	-155.9	-164.5	148.9	0	0	112.9	A230 A232 K238	A230-E234 PolarHBondContact O-N 3.37Å; A230-E234 VanDerWaalsContact O-N 3.17Å; A232-E234 VanDerWaalsContact C-N 3.35Å; A232-E234 PolarHBondContact O-N 2.9Å; E234-K238 WeakPolarHBondContact O-CB 3.48Å; E234-K238 VanDerWaalsContact O-CG 3.29Å; E234-K238 WeakPolarHBondContact O-CG 3.05Å; E234-K238 PolarHBondContact O-N 3.05Å; E234-K238 IonicContact OE1-NZ 2.68Å; E234-K238 PolarHBondContact OE1-NZ 2.86Å
235	L	50.2	Low	48.2	Very low	122 Å²	122	100.9 Å²	100.9	64%	0.639	54%	0.538	S	S	*	.	H	α-helix	trans	-78.2	-38.6	177.5	-127.2	96.9	0	0	0	111.8	Q231 A232 Q233 K238 A239	Q231-L235 PolarHBondContact O-N 2.98Å; A232-L235 PolarHBondContact O-N 3.39Å; Q233-L235 VanDerWaalsContact C-N 3.27Å; Q233-L235 PolarHBondContact O-N 2.98Å; L235-K238 PolarHBondContact O-N 3.31Å; L235-A239 WeakPolarHBondContact O-CB 3.44Å; L235-A239 PolarHBondContact O-N 3.49Å
236	E	56.2	Low	47.9	Very low	89 Å²	89	105 Å²	105	42%	0.416	56%	0.555	S	S	.	*	H	α-helix	trans	-64.9	-48.8	174.7	-78.4	174.2	171.1	0	0	110.8	A232 Q233 K238 A239 E240	A232-E236 PolarHBondContact O-N 2.87Å; Q233-E236 PolarHBondContact O-N 2.7Å; E236-K238 VanDerWaalsContact C-N 3.26Å; E236-K238 PolarHBondContact O-N 2.94Å; E236-A239 PolarHBondContact O-N 3.47Å; E236-A239 VanDerWaalsContact O-N 3.11Å; E236-E240 WeakPolarHBondContact O-CG 3.49Å; E236-E240 PolarHBondContact O-N 3.08Å
237	T	53.8	Low	47.5	Very low	74 Å²	74	104.6 Å²	104.6	45%	0.454	56%	0.56	S	S	.	*	H	α-helix	trans	-60.3	-37.2	176.2	-49.4	0	0	0	0	111.6	Q233 L241	Q233-T237 WeakPolarHBondContact O-CB 3.26Å; Q233-T237 PolarHBondContact O-N 3.35Å; Q233-T237 PolarHBondContact O-OG1 3.09Å; T237-L241 HydrophobicContact CG2-CD1 4.02Å; T237-L241 HydrophobicContact CG2-CG 4.47Å; T237-L241 VanDerWaalsContact O-CB 3.3Å; T237-L241 WeakPolarHBondContact O-CB 3.35Å; T237-L241 WeakPolarHBondContact O-CD1 3.28Å; T237-L241 WeakPolarHBondContact O-CG 3.38Å; T237-L241 PolarHBondContact O-N 2.97Å
238	K	55.4	Low	47.2	Very low	91 Å²	91	104.2 Å²	104.2	40%	0.396	57%	0.568	S	S	.	*	H	α-helix	trans	-70.9	-36.4	176.1	-81.5	174.8	174.7	163.4	0	113	E234 L235 E236 L242	E234-K238 WeakPolarHBondContact O-CB 3.48Å; E234-K238 VanDerWaalsContact O-CG 3.29Å; E234-K238 WeakPolarHBondContact O-CG 3.05Å; E234-K238 PolarHBondContact O-N 3.05Å; E234-K238 IonicContact OE1-NZ 2.68Å; E234-K238 PolarHBondContact OE1-NZ 2.86Å; L235-K238 PolarHBondContact O-N 3.31Å; E236-K238 VanDerWaalsContact C-N 3.26Å; E236-K238 PolarHBondContact O-N 2.94Å; K238-L242 WeakPolarHBondContact O-CB 3.32Å; K238-L242 WeakPolarHBondContact O-CD1 3.42Å; K238-L242 WeakPolarHBondContact O-CG 3.19Å; K238-L242 PolarHBondContact O-N 3.4Å; K238-L242 VanDerWaalsContact O-N 3.17Å
239	A	57.9	Low	47	Very low	50 Å²	50	107.4 Å²	107.4	41%	0.413	58%	0.576	S	S	.	*	H	α-helix	trans	-70.4	-40.4	177.4	0	0	0	0	0	111.7	L235 E236 L242 Q243	L235-A239 WeakPolarHBondContact O-CB 3.44Å; L235-A239 PolarHBondContact O-N 3.49Å; E236-A239 PolarHBondContact O-N 3.47Å; E236-A239 VanDerWaalsContact O-N 3.11Å; A239-L242 PolarHBondContact O-N 3.34Å; A239-Q243 WeakPolarHBondContact O-CG 3.27Å; A239-Q243 PolarHBondContact O-N 3.16Å; A239-Q243 VanDerWaalsContact O-N 3.15Å
240	E	58.3	Low	47	Very low	129 Å²	129	105.6 Å²	105.6	60%	0.603	58%	0.578	S	S	*	*	H	α-helix	trans	-65.3	-43.8	174.6	-73.6	178.1	167.9	0	0	111.9	E236 L242 Q243 S244	E236-E240 WeakPolarHBondContact O-CG 3.49Å; E236-E240 PolarHBondContact O-N 3.08Å; E240-L242 VanDerWaalsContact C-N 3.31Å; E240-L242 PolarHBondContact O-N 3.26Å; E240-Q243 PolarHBondContact O-N 3.19Å; E240-Q243 VanDerWaalsContact O-N 3.13Å; E240-S244 PolarHBondContact O-N 2.97Å; E240-S244 PolarHBondContact O-OG 3.26Å
241	L	54.3	Low	46.6	Very low	100 Å²	100	109.5 Å²	109.5	52%	0.524	59%	0.589	S	S	.	*	H	α-helix	trans	-61.5	-38.7	177.2	-76.2	169.9	0	0	0	112.6	T237 Q243 S244 D245	T237-L241 HydrophobicContact CG2-CD1 4.02Å; T237-L241 HydrophobicContact CG2-CG 4.47Å; T237-L241 VanDerWaalsContact O-CB 3.3Å; T237-L241 WeakPolarHBondContact O-CB 3.35Å; T237-L241 WeakPolarHBondContact O-CD1 3.28Å; T237-L241 WeakPolarHBondContact O-CG 3.38Å; T237-L241 PolarHBondContact O-N 2.97Å; L241-Q243 VanDerWaalsContact C-N 3.33Å; L241-S244 VanDerWaalsContact CA-OG 3.3Å; L241-S244 WeakPolarHBondContact CA-OG 3.37Å; L241-S244 PolarHBondContact O-N 3.35Å; L241-S244 PolarHBondContact O-OG 3.46Å; L241-D245 PolarHBondContact O-N 3.06Å
242	L	53.8	Low	46.1	Very low	125 Å²	125	109.4 Å²	109.4	65%	0.654	60%	0.602	S	S	*	*	H	α-helix	trans	-69.4	-30.2	176.6	-72.8	167.2	0	0	0	112.5	K238 A239 E240	K238-L242 WeakPolarHBondContact O-CB 3.32Å; K238-L242 WeakPolarHBondContact O-CD1 3.42Å; K238-L242 WeakPolarHBondContact O-CG 3.19Å; K238-L242 PolarHBondContact O-N 3.4Å; K238-L242 VanDerWaalsContact O-N 3.17Å; A239-L242 PolarHBondContact O-N 3.34Å; E240-L242 VanDerWaalsContact C-N 3.31Å; E240-L242 PolarHBondContact O-N 3.26Å
243	Q	50.6	Low	46.2	Very low	140 Å²	140	113.3 Å²	113.3	65%	0.654	62%	0.624	S	S	*	*	H	α-helix	trans	-78.7	-29.7	174.8	-73.5	-179.7	0.2	0	0	112.7	A239 E240 L241	A239-Q243 WeakPolarHBondContact O-CG 3.27Å; A239-Q243 PolarHBondContact O-N 3.16Å; A239-Q243 VanDerWaalsContact O-N 3.15Å; E240-Q243 PolarHBondContact O-N 3.19Å; E240-Q243 VanDerWaalsContact O-N 3.13Å; L241-Q243 VanDerWaalsContact C-N 3.33Å
244	S	47.4	Very low	45.3	Very low	69 Å²	69	116.1 Å²	116.1	48%	0.483	64%	0.637	S	S	.	*	H	α-helix	trans	-74	-30.9	175.8	51	0	0	0	0	113.6	E240 L241 E246 N247	E240-S244 PolarHBondContact O-N 2.97Å; E240-S244 PolarHBondContact O-OG 3.26Å; L241-S244 VanDerWaalsContact CA-OG 3.3Å; L241-S244 WeakPolarHBondContact CA-OG 3.37Å; L241-S244 PolarHBondContact O-N 3.35Å; L241-S244 PolarHBondContact O-OG 3.46Å; S244-E246 VanDerWaalsContact C-N 3.34Å; S244-E246 PolarHBondContact O-N 3.19Å; S244-N247 PolarHBondContact O-N 3.1Å
245	D	46.7	Very low	44.1	Very low	138 Å²	138	120 Å²	120	74%	0.738	65%	0.652	S	S	*	*	H	α-helix	trans	-74.5	-19.1	-179.8	-90.7	-12.1	0	0	0	113.6	L241 N247	L241-D245 PolarHBondContact O-N 3.06Å; D245-N247 VanDerWaalsContact C-N 3.34Å
246	E	43.7	Very low	43.1	Very low	170 Å²	170	120.7 Å²	120.7	79%	0.794	66%	0.662	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.9	-12.2	176	-88.1	-169.7	139.7	0	0	114	S244	S244-E246 VanDerWaalsContact C-N 3.34Å; S244-E246 PolarHBondContact O-N 3.19Å
247	N	41.7	Very low	41.8	Very low	148 Å²	148	121.1 Å²	121.1	79%	0.791	68%	0.68	S	S	*	*	T	Hydrogen-bonded Turn	trans	-112.3	8.1	-175.8	-76.3	-27.6	0	0	0	115.3	S244 D245	S244-N247 PolarHBondContact O-N 3.1Å; D245-N247 VanDerWaalsContact C-N 3.34Å
248	G	34.5	Very low	40.7	Very low	58 Å²	58	124.8 Å²	124.8	60%	0.598	70%	0.696	S	S	*	*			trans	-105.8	92.5	-176.5	0	0	0	0	0	114.8
249	I	33	Very low	39.3	Very low	158 Å²	158	127.5 Å²	127.5	81%	0.81	72%	0.721	S	S	*	*			trans	-85.6	122.7	162.7	-58.7	171.7	0	0	0	108.5
250	P	36.9	Very low	37.9	Very low	113 Å²	113	131.8 Å²	131.8	73%	0.734	74%	0.736	S	S	*	*			trans	-97.5	124.1	178.3	33.6	-26.4	0	0	0	111.6
251	N	28.2	Very low	36.4	Very low	149 Å²	149	131.8 Å²	131.8	80%	0.797	74%	0.74	S	S	*	*			trans	-127.2	91.5	163.9	-89.2	-18.8	0	0	0	110.6
252	S	29	Very low	35.2	Very low	116 Å²	116	133.9 Å²	133.9	81%	0.811	75%	0.751	S	S	*	*				50.4	157.3	128.2	113.5	0	0	0	0	121.9
253	P	45.1	Very low	34	Very low	114 Å²	114	134.8 Å²	134.8	74%	0.74	76%	0.757	S	S	*	*			trans	-120.5	151.7	-130.5	39.3	-26.5	0	0	0	115.4
254	Q	24.1	Very low	33.2	Very low	178 Å²	178	136.1 Å²	136.1	83%	0.832	77%	0.767	S	S	*	*			trans	-171.9	141.7	146.4	-119	174.7	-5.1	0	0	117.2
255	K	25	Very low	32.3	Very low	188 Å²	188	142 Å²	142	82%	0.817	79%	0.787	S	S	*	*			trans	94.6	105.6	142	-93.1	176.1	176.6	178.7	0	121.3
256	V	30.4	Very low	31.4	Very low	138 Å²	138	144.3 Å²	144.3	84%	0.836	79%	0.791	S	S	*	*			trans	-54.5	135.7	153.4	177.9	0	0	0	0	112.4
257	A	28.2	Very low	30.6	Very low	98 Å²	98	144.2 Å²	144.2	81%	0.81	79%	0.79	S	S	*	*			trans	-170.6	130.3	137.7	0	0	0	0	0	111.7
258	L	30.8	Very low	29.9	Very low	151 Å²	151	145 Å²	145	79%	0.791	79%	0.793	S	S	*	*			trans	-68.9	148.4	167.9	-84.7	109.8	0	0	0	112.2
259	T	25.9	Very low	29.6	Very low	148 Å²	148	151.3 Å²	151.3	91%	0.908	81%	0.807	S	S	*	*				-167.8	142.2	128.6	34.4	0	0	0	0	112.1
260	L	28.2	Very low	29.2	Very low	139 Å²	139	149.2 Å²	149.2	73%	0.728	81%	0.807	S	S	*	*			trans	-76	156.3	179.4	-96.2	88.2	0	0	0	114.4
261	D	26.9	Very low	28.8	Very low	129 Å²	129	151.6 Å²	151.6	69%	0.69	81%	0.808	S	S	*	*			trans	88.8	115.1	138.7	-75.2	-12.3	0	0	0	123.4
262	L	29.5	Very low	29	Very low	144 Å²	144	150.1 Å²	150.1	75%	0.754	81%	0.806	S	S	*	*			trans	98.5	131.3	130.1	-69.8	162.9	0	0	0	121.6
263	D	27.3	Very low	29	Very low	145 Å²	145	152.4 Å²	152.4	78%	0.775	81%	0.81	S	S	*	*			trans	89.6	86.6	158.5	-59.8	-21.4	0	0	0	121
264	L	33.7	Very low	28.3	Very low	167 Å²	167	154.6 Å²	154.6	87%	0.874	81%	0.81	S	S	*	*				44.5	96	119.5	-159.6	76.6	0	0	0	118.8
265	E	29.6	Very low	28.8	Very low	192 Å²	192	151.8 Å²	151.8	90%	0.897	81%	0.807	S	S	*	*			trans	-162.6	105	137	-109.2	170.8	-179	0	0	111
266	K	27.7	Very low	29.2	Very low	188 Å²	188	151.8 Å²	151.8	82%	0.817	81%	0.81	S	S	*	*			trans	21.1	111.1	142.7	-114.7	177.6	179.3	-178.8	0	118.4
267	E	26.4	Very low	29.4	Very low	167 Å²	167	154.5 Å²	154.5	78%	0.78	81%	0.811	S	S	*	*				159.3	142.5	107	-79.2	-155.2	164.5	0	0	113.1
268	L	28.4	Very low	29.9	Very low	164 Å²	164	154.4 Å²	154.4	86%	0.859	80%	0.804	S	S	*	*			trans	71.8	67.9	173.8	-94.7	79.9	0	0	0	117.8	S270	L268-S270 PolarHBondContact O-N 2.88Å
269	E	26.5	Very low	30.7	Very low	191 Å²	191	149.9 Å²	149.9	89%	0.893	79%	0.794	S	S	*	*			trans	-71.9	109.4	145.3	-74.4	-179.6	161.4	0	0	107.9	E271	E269-E271 PolarHBondContact O-N 3.3Å; E269-E271 VanDerWaalsContact O-N 3.12Å
270	S	26.2	Very low	32.3	Very low	114 Å²	114	150.6 Å²	150.6	80%	0.797	79%	0.785	S	S	*	*			trans	-64	104.7	160.2	51.6	0	0	0	0	107.3	L268	L268-S270 PolarHBondContact O-N 2.88Å
271	E	28.1	Very low	34.2	Very low	164 Å²	164	145.6 Å²	145.6	77%	0.766	76%	0.76	S	S	*	*			trans	-50	138	165.6	-71.7	-128.7	134.3	0	0	108.9	E269 D273	E269-E271 PolarHBondContact O-N 3.3Å; E269-E271 VanDerWaalsContact O-N 3.12Å; E271-D273 PolarHBondContact O-N 2.88Å
272	P	32.2	Very low	36.9	Very low	117 Å²	117	142.3 Å²	142.3	76%	0.76	75%	0.748	S	S	*	*			trans	-60.7	117.4	168.2	25.2	-28.8	0	0	0	106.8	E274	P272-E274 PolarHBondContact O-N 2.79Å
273	D	29.7	Very low	39.6	Very low	165 Å²	165	137 Å²	137	88%	0.882	72%	0.721	S	S	*	*			trans	-41.7	109.9	175.9	-91	-42.1	0	0	0	109	E271	E271-D273 PolarHBondContact O-N 2.88Å
274	E	29.2	Very low	42.4	Very low	160 Å²	160	136.3 Å²	136.3	75%	0.748	71%	0.711	S	S	*	*			trans	-51.1	135.7	167.2	-81.5	-164.5	144.2	0	0	107.3	P272 Q276	P272-E274 PolarHBondContact O-N 2.79Å; E274-Q276 PolarHBondContact O-N 2.96Å
275	P	35.9	Very low	45.1	Very low	118 Å²	118	131.1 Å²	131.1	77%	0.766	69%	0.686	S	S	*	*			trans	-57.7	110.9	174	22.7	-30.4	0	0	0	107.9	K277	P275-K277 PolarHBondContact O-N 2.99Å
276	Q	33.3	Very low	48	Very low	188 Å²	188	122 Å²	122	88%	0.879	64%	0.644	S	S	*	*			trans	-48	108.8	-178.4	-165.3	172.3	10.8	0	0	108.4	E274 S278	E274-Q276 PolarHBondContact O-N 2.96Å; Q276-S278 PolarHBondContact O-N 3.33Å
277	K	32.9	Very low	51	Low	196 Å²	196	116.4 Å²	116.4	85%	0.852	62%	0.619	S	S	*	*			trans	-56.3	104	171.9	-85.2	173	177.7	160.3	0	107.2	P275 G279	P275-K277 PolarHBondContact O-N 2.99Å; K277-G279 PolarHBondContact O-N 3.5Å
278	S	39.3	Very low	54.2	Low	96 Å²	96	113.6 Å²	113.6	67%	0.671	61%	0.607	S	S	*	*			trans	-54.1	94.7	177.5	165	0	0	0	0	110.3	Q276	Q276-S278 PolarHBondContact O-N 3.33Å
279	G	48.7	Very low	57.3	Low	56 Å²	56	109.5 Å²	109.5	58%	0.577	58%	0.582	S	S	*	*	P	Polyproline II helix	trans	-65.7	158.4	169.9	0	0	0	0	0	110.9	K277	K277-G279 PolarHBondContact O-N 3.5Å
280	K	59.5	Low	60.5	Low	163 Å²	163	100.4 Å²	100.4	71%	0.709	54%	0.539	S	S	*	.	P	Polyproline II helix	trans	-48.1	143.1	175.1	-60.9	174.3	179.4	-176.6	0	110.6	S282	K280-S282 PolarHBondContact O-N 2.91Å; K280-S282 VanDerWaalsContact O-N 3.13Å
281	P	67.8	Low	63.7	Low	33 Å²	33	101.5 Å²	101.5	21%	0.214	53%	0.526	C	S	.	.	P	Polyproline II helix	trans	-57.5	122.7	178.6	22.6	-31.7	0	0	0	109.7	V283 E426 V429	P281-V283 PolarHBondContact O-N 3.38Å; P281-E426 HydrophobicContact CB-CG 4.12Å; P281-V429 HydrophobicContact CG-CG2 4.24Å
282	S	83.9	Confident	66.9	Low	61 Å²	61	97.1 Å²	97.1	43%	0.427	51%	0.508	S	S	.	.	P	Polyproline II helix	trans	-75.8	117.3	180	178	0	0	0	0	109.5	K280 F284 V285 V286	K280-S282 PolarHBondContact O-N 2.91Å; K280-S282 VanDerWaalsContact O-N 3.13Å; S282-F284 PolarHBondContact O-N 3.18Å; S282-F284 VanDerWaalsContact O-N 3.1Å; S282-V285 PolarHBondContact O-N 3.48Å; S282-V286 PolarHBondContact O-N 3.31Å; S282-V286 VanDerWaalsContact O-N 3.13Å
283	V	85.1	Confident	69.9	Low	33 Å²	33	91.8 Å²	91.8	20%	0.2	47%	0.473	C	S	.	.	H	α-helix	trans	-51.7	-36.2	178.8	179.2	0	0	0	0	111.6	P281 V286 F287 V429 L433	P281-V283 PolarHBondContact O-N 3.38Å; V283-V286 PolarHBondContact O-N 2.97Å; V283-F287 WeakPolarHBondContact O-CB 3.38Å; V283-F287 PolarHBondContact O-N 3.41Å; V283-V429 HydrophobicContact CG2-CG1 4.18Å; V283-L433 HydrophobicContact CG1-CD1 4.07Å; V283-L433 HydrophobicContact CG1-CD2 3.82Å; V283-L433 HydrophobicContact CG1-CG 4.31Å
284	F	87.5	Confident	73	Confident	129 Å²	129	84 Å²	84	57%	0.566	43%	0.431	S	S	*	.	H	α-helix	trans	-67.2	-40.6	179.3	-176	-101.9	0	0	0	112.8	S282 F287 Q288	S282-F284 PolarHBondContact O-N 3.18Å; S282-F284 VanDerWaalsContact O-N 3.1Å; F284-F287 PolarHBondContact O-N 2.82Å; F284-Q288 HydrophobicContact CD1-CG 4.45Å; F284-Q288 VanDerWaalsContact CE1-CD 3.49Å; F284-Q288 HydrophobicContact CE1-CG 4.1Å; F284-Q288 HydrophobicContact CZ-CG 4.28Å; F284-Q288 WeakPolarHBondContact O-CG 3.16Å; F284-Q288 PolarHBondContact O-N 2.98Å
285	V	89.2	Confident	76.2	Confident	58 Å²	58	80.1 Å²	80.1	35%	0.352	42%	0.415	S	S	.	.	H	α-helix	trans	-66.3	-43.1	177.1	174.8	0	0	0	0	110.2	S282 F287 Q288 K289	S282-V285 PolarHBondContact O-N 3.48Å; V285-F287 VanDerWaalsContact C-N 3.34Å; V285-F287 PolarHBondContact O-N 2.97Å; V285-Q288 PolarHBondContact O-N 3.44Å; V285-K289 WeakPolarHBondContact O-CG 3.36Å; V285-K289 PolarHBondContact O-N 3.12Å
286	V	90.4	Very high	79.1	Confident	0 Å²	0	74.7 Å²	74.7	0%	0	38%	0.38	C	S	.	.	H	α-helix	trans	-60.9	-44.8	175.7	-178.1	0	0	0	0	110.7	S282 V283 Q288 K289 I290 V422 E426 V429 A430 L433	S282-V286 PolarHBondContact O-N 3.31Å; S282-V286 VanDerWaalsContact O-N 3.13Å; V283-V286 PolarHBondContact O-N 2.97Å; V286-Q288 PolarHBondContact O-N 3.44Å; V286-K289 PolarHBondContact O-N 3.14Å; V286-K289 VanDerWaalsContact O-N 3.15Å; V286-I290 WeakPolarHBondContact O-CG1 3.48Å; V286-I290 PolarHBondContact O-N 3.43Å; V286-V422 HydrophobicContact CG1-CG1 4.15Å; V286-E426 HydrophobicContact CG2-CB 3.84Å; V286-E426 HydrophobicContact CG2-CG 3.9Å; V286-V429 HydrophobicContact CB-CG1 4.33Å; V286-V429 HydrophobicContact CG1-CB 4.44Å; V286-V429 HydrophobicContact CG1-CG1 4.26Å; V286-V429 HydrophobicContact CG2-CB 4.46Å; V286-V429 HydrophobicContact CG2-CG1 4.28Å; V286-A430 HydrophobicContact CG1-CB 3.86Å; V286-L433 HydrophobicContact CB-CD1 4.22Å; V286-L433 HydrophobicContact CG1-CD1 3.99Å
287	F	91.9	Very high	82.1	Confident	71 Å²	71	65.8 Å²	65.8	31%	0.311	34%	0.338	S	S	.	.	H	α-helix	trans	-57.8	-46.1	175.1	167.9	-111.1	0	0	0	112.2	V283 F284 V285 K289 I290 W291 L433 F437	V283-F287 WeakPolarHBondContact O-CB 3.38Å; V283-F287 PolarHBondContact O-N 3.41Å; F284-F287 PolarHBondContact O-N 2.82Å; V285-F287 VanDerWaalsContact C-N 3.34Å; V285-F287 PolarHBondContact O-N 2.97Å; F287-K289 PolarHBondContact O-N 3.03Å; F287-I290 PolarHBondContact O-N 3.08Å; F287-W291 HydrophobicContact CE2-CB 4.07Å; F287-W291 HydrophobicContact CZ-CB 4.16Å; F287-W291 WeakPolarHBondContact O-CA 3.49Å; F287-W291 WeakPolarHBondContact O-CB 3.26Å; F287-W291 PolarHBondContact O-N 2.82Å; F287-L433 HydrophobicContact CB-CD1 4.25Å; F287-F437 AromaticContact CD2-CE2 3.68Å; F287-F437 HydrophobicContact CD2-CE2 3.68Å; F287-F437 AromaticContact CD2-CZ 3.49Å; F287-F437 HydrophobicContact CD2-CZ 3.49Å; F287-F437 VanDerWaalsContact CD2-CZ 3.49Å; F287-F437 HydrophobicContact CE2-CE1 4.07Å; F287-F437 AromaticContact CE2-CE2 3.87Å; F287-F437 HydrophobicContact CE2-CE2 3.87Å; F287-F437 AromaticContact CE2-CZ 3.25Å; F287-F437 HydrophobicContact CE2-CZ 3.25Å; F287-F437 HydrophobicContact CZ-CZ 4.32Å
288	Q	92.6	Very high	85.2	Confident	109 Å²	109	57.1 Å²	57.1	51%	0.509	30%	0.302	S	S	.	.	H	α-helix	trans	-60.8	-27.7	177.8	-77.2	-175.1	-29.2	0	0	113.4	F284 V285 V286	F284-Q288 HydrophobicContact CD1-CG 4.45Å; F284-Q288 VanDerWaalsContact CE1-CD 3.49Å; F284-Q288 HydrophobicContact CE1-CG 4.1Å; F284-Q288 HydrophobicContact CZ-CG 4.28Å; F284-Q288 WeakPolarHBondContact O-CG 3.16Å; F284-Q288 PolarHBondContact O-N 2.98Å; V285-Q288 PolarHBondContact O-N 3.44Å; V286-Q288 PolarHBondContact O-N 3.44Å
289	K	92.6	Very high	88	Confident	78 Å²	78	54.8 Å²	54.8	34%	0.339	28%	0.281	S	S	.	.	H	α-helix	trans	-75	-41.6	175.1	-67.3	174	-178	174	0	112	V285 V286 F287 V422 E426	V285-K289 WeakPolarHBondContact O-CG 3.36Å; V285-K289 PolarHBondContact O-N 3.12Å; V286-K289 PolarHBondContact O-N 3.14Å; V286-K289 VanDerWaalsContact O-N 3.15Å; F287-K289 PolarHBondContact O-N 3.03Å; K289-V422 HydrophobicContact CB-CG1 3.99Å; K289-V422 HydrophobicContact CD-CG1 4.14Å; K289-E426 IonicContact NZ-OE1 2.89Å; K289-E426 PolarHBondContact NZ-OE1 3.29Å; K289-E426 IonicContact NZ-OE2 2.72Å; K289-E426 PolarHBondContact NZ-OE2 2.85Å
290	I	93.8	Very high	90.4	Very high	0 Å²	0	52.1 Å²	52.1	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-98.2	1.2	-172.5	70.3	178.3	0	0	0	114.8	V286 F287 L292 T293 A294 A418 Q421 V422 A430 L433 M434	V286-I290 WeakPolarHBondContact O-CG1 3.48Å; V286-I290 PolarHBondContact O-N 3.43Å; F287-I290 PolarHBondContact O-N 3.08Å; I290-L292 VanDerWaalsContact C-N 3.28Å; I290-L292 PolarHBondContact O-N 3.12Å; I290-L292 VanDerWaalsContact O-N 3.13Å; I290-T293 PolarHBondContact O-N 3.1Å; I290-T293 VanDerWaalsContact O-N 3.07Å; I290-A294 WeakPolarHBondContact O-CB 3.4Å; I290-A294 PolarHBondContact O-N 3.26Å; I290-A418 HydrophobicContact CB-CB 4.35Å; I290-A418 HydrophobicContact CG2-CB 4.25Å; I290-A418 WeakPolarHBondContact CG2-O 3.29Å; I290-Q421 HydrophobicContact CG2-CB 4.34Å; I290-V422 HydrophobicContact CG2-CG1 3.54Å; I290-A430 HydrophobicContact CD1-CB 4.31Å; I290-A430 HydrophobicContact CG2-CB 4.45Å; I290-L433 HydrophobicContact CD1-CB 4.02Å; I290-L433 HydrophobicContact CD1-CD1 4.24Å; I290-M434 HydrophobicContact CD1-CG 4.25Å; I290-M434 HydrophobicContact CD1-SD 4.23Å
291	W	94.4	Very high	92.2	Very high	136 Å²	136	45 Å²	45	52%	0.515	22%	0.223	S	C	.	.	H	α-helix	trans	-54.2	-39.6	-166.4	77.2	-79.2	0	0	0	113.9	F287 A294 L295	F287-W291 HydrophobicContact CE2-CB 4.07Å; F287-W291 HydrophobicContact CZ-CB 4.16Å; F287-W291 WeakPolarHBondContact O-CA 3.49Å; F287-W291 WeakPolarHBondContact O-CB 3.26Å; F287-W291 PolarHBondContact O-N 2.82Å; W291-A294 PolarHBondContact O-N 3.12Å; W291-L295 HydrophobicContact CZ3-CD2 4.16Å; W291-L295 VanDerWaalsContact O-CB 3.32Å; W291-L295 WeakPolarHBondContact O-CB 3.5Å; W291-L295 PolarHBondContact O-N 3Å
292	L	94.6	Very high	93.6	Very high	73 Å²	73	44 Å²	44	38%	0.382	22%	0.217	S	C	.	.	H	α-helix	trans	-68.8	-43.5	-178.9	-177.4	63.6	0	0	0	111.1	I290 L295 C296 P362	I290-L292 VanDerWaalsContact C-N 3.28Å; I290-L292 PolarHBondContact O-N 3.12Å; I290-L292 VanDerWaalsContact O-N 3.13Å; L292-L295 PolarHBondContact O-N 3.17Å; L292-C296 PolarHBondContact O-N 2.71Å; L292-C296 PolarHBondContact O-SG 3.21Å; L292-P362 HydrophobicContact CD1-CG 4.2Å; L292-P362 HydrophobicContact CD2-CG 4.24Å; L292-P362 HydrophobicContact CG-CG 4.36Å
293	T	94.7	Very high	94.2	Very high	5 Å²	5	41.2 Å²	41.2	3%	0.031	20%	0.197	C	C	.	.	H	α-helix	trans	-65	-42	176.6	-49.3	0	0	0	0	110.9	I290 C296 L297 T414 L417 A418 Q421 M434	I290-T293 PolarHBondContact O-N 3.1Å; I290-T293 VanDerWaalsContact O-N 3.07Å; T293-C296 WeakPolarHBondContact O-CB 3.44Å; T293-C296 PolarHBondContact O-N 3.45Å; T293-L297 PolarHBondContact O-N 3.4Å; T293-T414 HydrophobicContact CG2-CG2 4.03Å; T293-T414 WeakPolarHBondContact CG2-O 3.27Å; T293-L417 HydrophobicContact CG2-CB 4.46Å; T293-A418 HydrophobicContact CG2-CB 3.99Å; T293-Q421 PolarHBondContact OG1-NE2 3.17Å; T293-Q421 PolarHBondContact OG1-OE1 3.2Å; T293-M434 HydrophobicContact CG2-CE 4.03Å
294	A	95.5	Very high	94.8	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-62.4	-44.4	174.3	0	0	0	0	0	112.1	I290 W291 C296 L297 V298 M434 F437	I290-A294 WeakPolarHBondContact O-CB 3.4Å; I290-A294 PolarHBondContact O-N 3.26Å; W291-A294 PolarHBondContact O-N 3.12Å; A294-C296 PolarHBondContact O-N 3.42Å; A294-L297 WeakPolarHBondContact O-CB 3.44Å; A294-L297 PolarHBondContact O-N 3.44Å; A294-V298 WeakPolarHBondContact O-CG2 3.45Å; A294-V298 PolarHBondContact O-N 3.34Å; A294-M434 HydrophobicContact CB-SD 4.01Å; A294-F437 HydrophobicContact CB-CB 4.2Å; A294-F437 HydrophobicContact CB-CD1 4.18Å; A294-F437 HydrophobicContact CB-CD2 3.52Å; A294-F437 HydrophobicContact CB-CE2 3.92Å; A294-F437 HydrophobicContact CB-CG 3.69Å; A294-F437 HydrophobicContact CB-CZ 4.42Å
295	L	96.6	Very high	95.2	Very high	80 Å²	80	35.4 Å²	35.4	42%	0.419	17%	0.17	S	C	.	.	H	α-helix	trans	-61.7	-43.8	175.3	178.5	63.1	0	0	0	111.4	W291 L292 L297 V298 L299	W291-L295 HydrophobicContact CZ3-CD2 4.16Å; W291-L295 VanDerWaalsContact O-CB 3.32Å; W291-L295 WeakPolarHBondContact O-CB 3.5Å; W291-L295 PolarHBondContact O-N 3Å; L292-L295 PolarHBondContact O-N 3.17Å; L295-L297 VanDerWaalsContact C-N 3.31Å; L295-L297 PolarHBondContact O-N 3.46Å; L295-V298 PolarHBondContact O-N 2.99Å; L295-L299 HydrophobicContact CD1-CD1 4.29Å; L295-L299 HydrophobicContact CD1-CG 4.22Å; L295-L299 HydrophobicContact CG-CD1 4.07Å; L295-L299 HydrophobicContact CG-CG 4.42Å; L295-L299 VanDerWaalsContact O-CG 3.28Å; L295-L299 WeakPolarHBondContact O-CG 3.2Å; L295-L299 PolarHBondContact O-N 3.37Å
296	C	97	Very high	95.5	Very high	4 Å²	4	32.8 Å²	32.8	3%	0.027	15%	0.154	C	C	.	.	H	α-helix	trans	-56.2	-46.7	175.4	-73.3	0	0	0	0	111.4	L292 T293 A294 L299 V300 V365 T414	L292-C296 PolarHBondContact O-N 2.71Å; L292-C296 PolarHBondContact O-SG 3.21Å; T293-C296 WeakPolarHBondContact O-CB 3.44Å; T293-C296 PolarHBondContact O-N 3.45Å; A294-C296 PolarHBondContact O-N 3.42Å; C296-L299 PolarHBondContact O-N 2.9Å; C296-V300 VanDerWaalsContact O-CG2 3.28Å; C296-V300 WeakPolarHBondContact O-CG2 3.28Å; C296-V300 PolarHBondContact O-N 3.46Å; C296-V365 HydrophobicContact CB-CG2 4.03Å; C296-T414 HydrophobicContact CB-CG2 3.97Å
297	L	96.6	Very high	95.7	Very high	0 Å²	0	32.8 Å²	32.8	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-60.2	-46.1	176.6	179.1	66.3	0	0	0	112.5	T293 A294 L295 L299 V300 F301 V411 M415 M434 F437 L438	T293-L297 PolarHBondContact O-N 3.4Å; A294-L297 WeakPolarHBondContact O-CB 3.44Å; A294-L297 PolarHBondContact O-N 3.44Å; L295-L297 VanDerWaalsContact C-N 3.31Å; L295-L297 PolarHBondContact O-N 3.46Å; L297-L299 VanDerWaalsContact C-N 3.33Å; L297-L299 PolarHBondContact O-N 2.88Å; L297-V300 PolarHBondContact O-N 3.1Å; L297-F301 HydrophobicContact CD1-CD2 3.74Å; L297-F301 HydrophobicContact CD1-CE2 3.57Å; L297-F301 HydrophobicContact CG-CD2 4.25Å; L297-F301 HydrophobicContact CG-CE2 4.44Å; L297-F301 PolarHBondContact O-N 2.95Å; L297-F301 VanDerWaalsContact O-N 3.13Å; L297-V411 HydrophobicContact CD1-CB 4.49Å; L297-V411 HydrophobicContact CD1-CG1 4.22Å; L297-V411 HydrophobicContact CD1-CG2 4.29Å; L297-M415 HydrophobicContact CD1-CE 4.44Å; L297-M415 HydrophobicContact CD2-CE 3.66Å; L297-M415 HydrophobicContact CD2-SD 4.23Å; L297-M434 HydrophobicContact CB-CE 4.21Å; L297-M434 HydrophobicContact CD2-CE 3.54Å; L297-M434 WeakPolarHBondContact CD2-O 3.47Å; L297-M434 HydrophobicContact CD2-SD 4.33Å; L297-M434 HydrophobicContact CG-CE 4.47Å; L297-F437 HydrophobicContact CD2-CB 4.48Å; L297-L438 HydrophobicContact CD2-CB 4.09Å
298	V	98	Very high	95.8	Very high	14 Å²	14	30.4 Å²	30.4	9%	0.085	14%	0.144	C	C	.	.	H	α-helix	trans	-56.8	-48.3	176.1	171.2	0	0	0	0	110.4	A294 L295 F301 T302 F437 L440 G441	A294-V298 WeakPolarHBondContact O-CG2 3.45Å; A294-V298 PolarHBondContact O-N 3.34Å; L295-V298 PolarHBondContact O-N 2.99Å; V298-F301 PolarHBondContact O-N 3.38Å; V298-T302 VanDerWaalsContact O-CB 3.24Å; V298-T302 WeakPolarHBondContact O-CB 3.36Å; V298-T302 PolarHBondContact O-N 3.31Å; V298-T302 PolarHBondContact O-OG1 2.88Å; V298-F437 HydrophobicContact CG2-CB 3.9Å; V298-F437 HydrophobicContact CG2-CD1 3.75Å; V298-F437 HydrophobicContact CG2-CG 4.3Å; V298-F437 VanDerWaalsContact CG2-O 3.28Å; V298-F437 WeakPolarHBondContact CG2-O 3.29Å; V298-L440 HydrophobicContact CG2-CB 4.44Å; V298-L440 HydrophobicContact CG2-CD2 4.12Å; V298-L440 HydrophobicContact CG2-CG 4.47Å; V298-G441 WeakPolarHBondContact O-CA 3.33Å
299	L	97.9	Very high	95.7	Very high	47 Å²	47	27.4 Å²	27.4	25%	0.246	13%	0.134	C	C	.	.	H	α-helix	trans	-65.9	-40.6	-177.9	-67.1	173.4	0	0	0	112.1	L295 C296 L297 T302 V303 V365 F369	L295-L299 HydrophobicContact CD1-CD1 4.29Å; L295-L299 HydrophobicContact CD1-CG 4.22Å; L295-L299 HydrophobicContact CG-CD1 4.07Å; L295-L299 HydrophobicContact CG-CG 4.42Å; L295-L299 VanDerWaalsContact O-CG 3.28Å; L295-L299 WeakPolarHBondContact O-CG 3.2Å; L295-L299 PolarHBondContact O-N 3.37Å; C296-L299 PolarHBondContact O-N 2.9Å; L297-L299 VanDerWaalsContact C-N 3.33Å; L297-L299 PolarHBondContact O-N 2.88Å; L299-T302 PolarHBondContact O-N 3.2Å; L299-V303 WeakPolarHBondContact O-CG2 3.17Å; L299-V303 PolarHBondContact O-N 3.2Å; L299-V365 HydrophobicContact CB-CG1 3.56Å; L299-V365 HydrophobicContact CD1-CG1 4.19Å; L299-F369 HydrophobicContact CB-CE2 4.31Å; L299-F369 HydrophobicContact CD2-CE2 4.24Å; L299-F369 HydrophobicContact CD2-CZ 3.87Å
300	V	98.1	Very high	95.4	Very high	0 Å²	0	25.3 Å²	25.3	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-57.4	-53	175.5	172.1	0	0	0	0	110.4	C296 L297 V303 T304 V365 N407 L410 V411	C296-V300 VanDerWaalsContact O-CG2 3.28Å; C296-V300 WeakPolarHBondContact O-CG2 3.28Å; C296-V300 PolarHBondContact O-N 3.46Å; L297-V300 PolarHBondContact O-N 3.1Å; V300-V303 PolarHBondContact O-N 3.41Å; V300-T304 WeakPolarHBondContact O-CB 3.49Å; V300-T304 PolarHBondContact O-N 2.84Å; V300-T304 PolarHBondContact O-OG1 3.23Å; V300-V365 HydrophobicContact CG2-CB 4.33Å; V300-V365 HydrophobicContact CG2-CG1 3.9Å; V300-V365 HydrophobicContact CG2-CG2 3.66Å; V300-N407 WeakPolarHBondContact CG1-OD1 3.15Å; V300-L410 HydrophobicContact CG2-CB 3.96Å; V300-L410 HydrophobicContact CG2-CD1 4.31Å; V300-V411 HydrophobicContact CG1-CG2 3.68Å
301	F	97.2	Very high	95.2	Very high	14 Å²	14	25.3 Å²	25.3	6%	0.061	13%	0.131	C	C	.	.	H	α-helix	trans	-69	-33.5	179.6	-83.6	-66.5	0	0	0	113.3	L297 V298 T304 L305 V411 L438 G441 L442	L297-F301 HydrophobicContact CD1-CD2 3.74Å; L297-F301 HydrophobicContact CD1-CE2 3.57Å; L297-F301 HydrophobicContact CG-CD2 4.25Å; L297-F301 HydrophobicContact CG-CE2 4.44Å; L297-F301 PolarHBondContact O-N 2.95Å; L297-F301 VanDerWaalsContact O-N 3.13Å; V298-F301 PolarHBondContact O-N 3.38Å; F301-T304 PolarHBondContact O-N 3.36Å; F301-L305 HydrophobicContact CD1-CD2 4.38Å; F301-L305 WeakPolarHBondContact O-CB 3.45Å; F301-L305 PolarHBondContact O-N 2.98Å; F301-V411 HydrophobicContact CD2-CG2 4.12Å; F301-V411 HydrophobicContact CE1-CG2 4.23Å; F301-V411 HydrophobicContact CE2-CB 4.28Å; F301-V411 HydrophobicContact CE2-CG1 3.75Å; F301-V411 HydrophobicContact CE2-CG2 3.48Å; F301-V411 VanDerWaalsContact CE2-CG2 3.48Å; F301-V411 HydrophobicContact CZ-CB 4.33Å; F301-V411 HydrophobicContact CZ-CG1 3.74Å; F301-V411 HydrophobicContact CZ-CG2 3.56Å; F301-L438 HydrophobicContact CD2-CD1 4.39Å; F301-L438 HydrophobicContact CD2-CG 3.92Å; F301-L438 HydrophobicContact CE2-CB 4.35Å; F301-L438 HydrophobicContact CE2-CD1 3.46Å; F301-L438 VanDerWaalsContact CE2-CD1 3.46Å; F301-L438 HydrophobicContact CE2-CG 3.46Å; F301-L438 VanDerWaalsContact CE2-CG 3.46Å; F301-L438 HydrophobicContact CZ-CD1 3.72Å; F301-L438 HydrophobicContact CZ-CG 3.93Å; F301-G441 CarbonylContact C-O 3.59Å; F301-L442 HydrophobicContact CB-CD2 4.38Å; F301-L442 HydrophobicContact CD1-CD2 3.46Å; F301-L442 VanDerWaalsContact CD1-CD2 3.46Å; F301-L442 HydrophobicContact CD1-CG 4.24Å; F301-L442 HydrophobicContact CE1-CD2 3.92Å; F301-L442 HydrophobicContact CG-CD2 4.09Å; F301-L442 HydrophobicContact CG-CG 4.45Å
302	T	97.6	Very high	95.1	Very high	13 Å²	13	18.9 Å²	18.9	8%	0.08	11%	0.107	C	C	.	.	H	α-helix	trans	-60	-51.5	175.6	-63	0	0	0	0	110.2	V298 L299 T304 S306 G441 C444 G445 L448	V298-T302 VanDerWaalsContact O-CB 3.24Å; V298-T302 WeakPolarHBondContact O-CB 3.36Å; V298-T302 PolarHBondContact O-N 3.31Å; V298-T302 PolarHBondContact O-OG1 2.88Å; L299-T302 PolarHBondContact O-N 3.2Å; T302-T304 VanDerWaalsContact C-N 3.33Å; T302-T304 PolarHBondContact O-N 2.93Å; T302-S306 WeakPolarHBondContact O-CB 3.36Å; T302-S306 PolarHBondContact O-N 3.05Å; T302-S306 PolarHBondContact O-OG 3.33Å; T302-G441 WeakPolarHBondContact CA-O 3.26Å; T302-G441 PolarHBondContact N-O 3.42Å; T302-C444 HydrophobicContact CG2-CB 4.06Å; T302-C444 WeakPolarHBondContact OG1-CB 3.44Å; T302-G445 WeakPolarHBondContact O-CA 3.48Å; T302-L448 HydrophobicContact CG2-CD1 3.53Å
303	V	97.6	Very high	94.9	Very high	1 Å²	1	16.9 Å²	16.9	1%	0.006	10%	0.101	C	C	.	.	H	α-helix	trans	-60.4	-46.3	175.5	172.8	0	0	0	0	110	L299 V300 S306 R368 F369 V372 F403	L299-V303 WeakPolarHBondContact O-CG2 3.17Å; L299-V303 PolarHBondContact O-N 3.2Å; V300-V303 PolarHBondContact O-N 3.41Å; V303-S306 PolarHBondContact O-N 3.02Å; V303-S306 PolarHBondContact O-OG 3.16Å; V303-R368 HydrophobicContact CG1-CB 4.09Å; V303-R368 WeakPolarHBondContact CG1-O 3.23Å; V303-F369 HydrophobicContact CG2-CD1 3.75Å; V303-F369 HydrophobicContact CG2-CD2 3.7Å; V303-F369 HydrophobicContact CG2-CE1 3.64Å; V303-F369 HydrophobicContact CG2-CE2 3.59Å; V303-F369 HydrophobicContact CG2-CG 3.78Å; V303-F369 HydrophobicContact CG2-CZ 3.55Å; V303-V372 HydrophobicContact CG1-CG2 4.07Å; V303-F403 HydrophobicContact CG1-CE2 4.25Å
304	T	97.4	Very high	94.6	Very high	2 Å²	2	19.7 Å²	19.7	1%	0.012	12%	0.115	C	C	.	.	H	α-helix	trans	-61.2	-53.1	-175.3	-61.5	0	0	0	0	112.8	V300 F301 T302 S306 V307 F308 F337 R368 F403 N407	V300-T304 WeakPolarHBondContact O-CB 3.49Å; V300-T304 PolarHBondContact O-N 2.84Å; V300-T304 PolarHBondContact O-OG1 3.23Å; F301-T304 PolarHBondContact O-N 3.36Å; T302-T304 VanDerWaalsContact C-N 3.33Å; T302-T304 PolarHBondContact O-N 2.93Å; T304-S306 VanDerWaalsContact C-N 3.3Å; T304-S306 PolarHBondContact O-N 3.45Å; T304-V307 PolarHBondContact O-N 2.81Å; T304-F308 WeakPolarHBondContact O-CB 3.48Å; T304-F308 PolarHBondContact O-N 3.47Å; T304-F337 HydrophobicContact CG2-CE2 4.02Å; T304-F337 HydrophobicContact CG2-CZ 3.82Å; T304-R368 PolarHBondContact OG1-NH2 3.36Å; T304-F403 HydrophobicContact CG2-CE1 4.2Å; T304-F403 HydrophobicContact CG2-CZ 3.93Å; T304-N407 WeakPolarHBondContact CB-OD1 3.18Å; T304-N407 PolarHBondContact OG1-OD1 3.05Å
305	L	95	Very high	94.3	Very high	39 Å²	39	19.8 Å²	19.8	20%	0.204	12%	0.115	C	C	.	.	H	α-helix	trans	-76.2	-18.1	-176.7	-88.1	-83.9	0	0	0	113	F301 V307 F308 L442 G445 S449	F301-L305 HydrophobicContact CD1-CD2 4.38Å; F301-L305 WeakPolarHBondContact O-CB 3.45Å; F301-L305 PolarHBondContact O-N 2.98Å; L305-V307 VanDerWaalsContact C-N 3.26Å; L305-V307 PolarHBondContact O-N 3.14Å; L305-F308 WeakPolarHBondContact CA-O 3.39Å; L305-L442 HydrophobicContact CD1-CD2 4.33Å; L305-L442 HydrophobicContact CD2-CD2 3.65Å; L305-L442 HydrophobicContact CG-CD2 3.65Å; L305-G445 CarbonylContact C-O 3.57Å; L305-S449 WeakPolarHBondContact O-CB 3.3Å
306	S	95.2	Very high	93.8	Very high	2 Å²	2	18.2 Å²	18.2	1%	0.014	11%	0.109	C	C	.	.	H	α-helix	trans	-66.8	-28.7	173.1	73.9	0	0	0	0	113.1	T302 V303 T304 G445 S449	T302-S306 WeakPolarHBondContact O-CB 3.36Å; T302-S306 PolarHBondContact O-N 3.05Å; T302-S306 PolarHBondContact O-OG 3.33Å; V303-S306 PolarHBondContact O-N 3.02Å; V303-S306 PolarHBondContact O-OG 3.16Å; T304-S306 VanDerWaalsContact C-N 3.3Å; T304-S306 PolarHBondContact O-N 3.45Å; S306-G445 VanDerWaalsContact CA-O 3.25Å; S306-G445 WeakPolarHBondContact CA-O 3.39Å; S306-G445 PolarHBondContact N-O 3.04Å; S306-S449 WeakPolarHBondContact O-CA 3.49Å; S306-S449 WeakPolarHBondContact O-CB 3.36Å
307	V	94.7	Very high	93.3	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-113.2	-39	179.8	-62.5	0	0	0	0	113.6	T304 L305 P309 A310 I311 T312 V372 F375 F403	T304-V307 PolarHBondContact O-N 2.81Å; L305-V307 VanDerWaalsContact C-N 3.26Å; L305-V307 PolarHBondContact O-N 3.14Å; V307-P309 CarbonylContact O-C 3.47Å; V307-A310 PolarHBondContact O-N 3.02Å; V307-I311 HydrophobicContact CB-CB 4.29Å; V307-I311 HydrophobicContact CB-CG1 4.48Å; V307-I311 WeakPolarHBondContact O-CA 3.44Å; V307-I311 VanDerWaalsContact O-CB 3.31Å; V307-I311 WeakPolarHBondContact O-CB 3.49Å; V307-I311 PolarHBondContact O-N 3.3Å; V307-T312 HydrophobicContact CB-CG2 4.4Å; V307-T312 PolarHBondContact O-N 3.41Å; V307-V372 HydrophobicContact CG1-CB 4.32Å; V307-V372 HydrophobicContact CG1-CG1 4.18Å; V307-V372 HydrophobicContact CG1-CG2 4.16Å; V307-F375 HydrophobicContact CB-CD2 4.35Å; V307-F375 HydrophobicContact CG2-CD2 3.96Å; V307-F375 HydrophobicContact CG2-CE2 4.42Å; V307-F403 HydrophobicContact CG2-CE1 4.25Å; V307-F403 HydrophobicContact CG2-CE2 3.79Å; V307-F403 HydrophobicContact CG2-CZ 3.4Å
308	F	93.8	Very high	92.5	Very high	21 Å²	21	21.6 Å²	21.6	9%	0.092	13%	0.133	C	C	.	.	T	Hydrogen-bonded Turn	trans	-103.5	127.6	-176.9	177	-91.1	0	0	0	111.6	T304 L305 T312 F334 F337 M400 F403	T304-F308 WeakPolarHBondContact O-CB 3.48Å; T304-F308 PolarHBondContact O-N 3.47Å; L305-F308 WeakPolarHBondContact CA-O 3.39Å; F308-T312 WeakPolarHBondContact CD2-OG1 3.37Å; F308-F334 HydrophobicContact CE2-CD1 4.17Å; F308-F334 HydrophobicContact CE2-CE1 4.48Å; F308-F334 AromaticContact CZ-CD1 3.9Å; F308-F334 HydrophobicContact CZ-CD1 3.9Å; F308-F334 HydrophobicContact CZ-CE1 4.28Å; F308-F337 HydrophobicContact CD1-CD1 4.14Å; F308-F337 HydrophobicContact CD1-CD2 4.38Å; F308-F337 AromaticContact CD1-CE1 3.94Å; F308-F337 HydrophobicContact CD1-CE1 3.94Å; F308-F337 HydrophobicContact CD1-CE2 4.18Å; F308-F337 HydrophobicContact CD1-CG 4.36Å; F308-F337 AromaticContact CD1-CZ 3.96Å; F308-F337 HydrophobicContact CD1-CZ 3.96Å; F308-F337 HydrophobicContact CD2-CB 4.39Å; F308-F337 HydrophobicContact CD2-CD2 4.14Å; F308-F337 HydrophobicContact CD2-CG 4.13Å; F308-F337 AromaticContact CE1-CD1 3.53Å; F308-F337 HydrophobicContact CE1-CD1 3.53Å; F308-F337 HydrophobicContact CE1-CD2 4.47Å; F308-F337 AromaticContact CE1-CE1 3.58Å; F308-F337 HydrophobicContact CE1-CE1 3.58Å; F308-F337 HydrophobicContact CE1-CG 4Å; F308-F337 HydrophobicContact CE1-CZ 4.09Å; F308-F337 HydrophobicContact CE2-CB 3.76Å; F308-F337 HydrophobicContact CE2-CD1 4.06Å; F308-F337 HydrophobicContact CE2-CD2 4.24Å; F308-F337 AromaticContact CE2-CG 3.75Å; F308-F337 HydrophobicContact CE2-CG 3.75Å; F308-F337 HydrophobicContact CG-CD2 4.22Å; F308-F337 HydrophobicContact CG-CE2 4.24Å; F308-F337 HydrophobicContact CG-CG 4.42Å; F308-F337 HydrophobicContact CG-CZ 4.48Å; F308-F337 HydrophobicContact CZ-CB 3.96Å; F308-F337 AromaticContact CZ-CD1 3.48Å; F308-F337 HydrophobicContact CZ-CD1 3.48Å; F308-F337 VanDerWaalsContact CZ-CD1 3.48Å; F308-F337 HydrophobicContact CZ-CD2 4.41Å; F308-F337 HydrophobicContact CZ-CE1 4.05Å; F308-F337 AromaticContact CZ-CG 3.68Å; F308-F337 HydrophobicContact CZ-CG 3.68Å; F308-M400 HydrophobicContact CD2-CE 4.35Å; F308-F403 HydrophobicContact CB-CE1 3.92Å; F308-F403 HydrophobicContact CB-CZ 4.26Å
309	P	90.4	Very high	91.5	Very high	47 Å²	47	25.1 Å²	25.1	31%	0.305	16%	0.155	S	C	.	.	T	Hydrogen-bonded Turn	cis	-89.7	-7.4	-4.3	35.2	-35	0	0	0	114	V307 I311 T312 A313 F334	V307-P309 CarbonylContact O-C 3.47Å; P309-I311 VanDerWaalsContact C-N 3.31Å; P309-I311 PolarHBondContact O-N 2.96Å; P309-I311 VanDerWaalsContact O-N 3.16Å; P309-T312 PolarHBondContact O-N 3.48Å; P309-A313 HydrophobicContact CB-CB 4.37Å; P309-A313 WeakPolarHBondContact O-CB 3.35Å; P309-A313 PolarHBondContact O-N 3.05Å; P309-F334 HydrophobicContact CB-CE1 3.65Å; P309-F334 HydrophobicContact CB-CZ 3.88Å; P309-F334 HydrophobicContact CG-CE1 4.34Å
310	A	87.2	Confident	89.6	Confident	34 Å²	34	27.4 Å²	27.4	28%	0.281	18%	0.175	S	C	.	.	T	Hydrogen-bonded Turn	trans	-56.2	-38.4	-164.5	0	0	0	0	0	114.9	V307 M314	V307-A310 PolarHBondContact O-N 3.02Å; A310-M314 WeakPolarHBondContact O-CG 3.34Å
311	I	90.1	Very high	88.3	Confident	0 Å²	0	33.3 Å²	33.3	0%	0	21%	0.213	C	C	.	.	T	Hydrogen-bonded Turn	trans	-94.8	-47.6	179.2	-54.5	-62.2	0	0	0	110	V307 P309 A313 M314 M376 F452 K453 L456	V307-I311 HydrophobicContact CB-CB 4.29Å; V307-I311 HydrophobicContact CB-CG1 4.48Å; V307-I311 WeakPolarHBondContact O-CA 3.44Å; V307-I311 VanDerWaalsContact O-CB 3.31Å; V307-I311 WeakPolarHBondContact O-CB 3.49Å; V307-I311 PolarHBondContact O-N 3.3Å; P309-I311 VanDerWaalsContact C-N 3.31Å; P309-I311 PolarHBondContact O-N 2.96Å; P309-I311 VanDerWaalsContact O-N 3.16Å; I311-A313 VanDerWaalsContact C-N 3.31Å; I311-A313 PolarHBondContact O-N 2.83Å; I311-M314 WeakPolarHBondContact O-CB 3.31Å; I311-M314 PolarHBondContact O-N 3.28Å; I311-M376 HydrophobicContact CG2-CG 4.37Å; I311-F452 HydrophobicContact CD1-CB 3.82Å; I311-F452 HydrophobicContact CG1-CB 4.27Å; I311-K453 HydrophobicContact CD1-CB 4.23Å; I311-L456 HydrophobicContact CD1-CD1 3.62Å; I311-L456 HydrophobicContact CG2-CD1 3.98Å
312	T	92.8	Very high	87.2	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	23%	0.23	C	C	.	.	G	3₁₀ helix	trans	-65.6	-31.6	-174.1	56.3	0	0	0	0	113	V307 F308 P309 M314 V315 C333 F375 F396 M400	V307-T312 HydrophobicContact CB-CG2 4.4Å; V307-T312 PolarHBondContact O-N 3.41Å; F308-T312 WeakPolarHBondContact CD2-OG1 3.37Å; P309-T312 PolarHBondContact O-N 3.48Å; T312-M314 VanDerWaalsContact C-N 3.25Å; T312-M314 PolarHBondContact O-N 3.09Å; T312-V315 WeakPolarHBondContact O-CB 3.25Å; T312-V315 PolarHBondContact O-N 3.32Å; T312-C333 PolarHBondContact OG1-SG 2.7Å; T312-F375 HydrophobicContact CG2-CB 4.39Å; T312-F375 HydrophobicContact CG2-CD1 3.87Å; T312-F375 HydrophobicContact CG2-CD2 4.2Å; T312-F375 HydrophobicContact CG2-CE1 4.18Å; T312-F375 HydrophobicContact CG2-CE2 4.47Å; T312-F375 HydrophobicContact CG2-CG 3.9Å; T312-F375 HydrophobicContact CG2-CZ 4.48Å; T312-F396 HydrophobicContact CG2-CE2 4.3Å; T312-M400 HydrophobicContact CG2-SD 3.98Å
313	A	89.9	Confident	86.4	Confident	32 Å²	32	42.1 Å²	42.1	26%	0.264	26%	0.261	S	S	.	.	G	3₁₀ helix	trans	-75.5	-10.9	175.9	0	0	0	0	0	113.6	P309 I311 N329 F334	P309-A313 HydrophobicContact CB-CB 4.37Å; P309-A313 WeakPolarHBondContact O-CB 3.35Å; P309-A313 PolarHBondContact O-N 3.05Å; I311-A313 VanDerWaalsContact C-N 3.31Å; I311-A313 PolarHBondContact O-N 2.83Å; A313-N329 PolarHBondContact O-ND2 3.41Å; A313-F334 HydrophobicContact CB-CE2 4.38Å; A313-F334 HydrophobicContact CB-CZ 4.23Å
314	M	88.1	Confident	85.8	Confident	63 Å²	63	47.1 Å²	47.1	31%	0.31	28%	0.28	S	S	.	.	G	3₁₀ helix	trans	-85.3	-11.5	172.2	-61.4	-179.6	63.8	0	0	112.6	A310 I311 T312 V380 K453	A310-M314 WeakPolarHBondContact O-CG 3.34Å; I311-M314 WeakPolarHBondContact O-CB 3.31Å; I311-M314 PolarHBondContact O-N 3.28Å; T312-M314 VanDerWaalsContact C-N 3.25Å; T312-M314 PolarHBondContact O-N 3.09Å; M314-V380 HydrophobicContact CB-CG1 4.23Å; M314-V380 HydrophobicContact CE-CG1 4.37Å; M314-K453 HydrophobicContact SD-CG 4.34Å
315	V	88.8	Confident	85.2	Confident	2 Å²	2	50 Å²	50	1%	0.012	30%	0.3	C	S	.	.			trans	-70.1	137.7	175	-178.2	0	0	0	0	108.9	T312 F328 N329 C378 H379 V380 F396	T312-V315 WeakPolarHBondContact O-CB 3.25Å; T312-V315 PolarHBondContact O-N 3.32Å; V315-F328 HydrophobicContact CG1-CE1 4.25Å; V315-N329 PolarHBondContact O-ND2 3.4Å; V315-N329 PolarHBondContact O-OD1 2.82Å; V315-N329 VanDerWaalsContact O-OD1 3.1Å; V315-C378 HydrophobicContact CG1-CB 4.19Å; V315-C378 HydrophobicContact CG2-CB 3.98Å; V315-H379 WeakPolarHBondContact CA-O 3.5Å; V315-V380 HydrophobicContact CG2-CG2 4.19Å; V315-F396 HydrophobicContact CB-CD2 4.12Å; V315-F396 HydrophobicContact CB-CE2 3.96Å; V315-F396 HydrophobicContact CB-CZ 4.42Å; V315-F396 HydrophobicContact CG1-CD2 3.83Å; V315-F396 HydrophobicContact CG1-CE2 4.17Å; V315-F396 HydrophobicContact CG1-CG 4.07Å; V315-F396 HydrophobicContact CG2-CD2 4Å; V315-F396 HydrophobicContact CG2-CE2 3.83Å
316	T	86.7	Confident	84.6	Confident	48 Å²	48	54 Å²	54	29%	0.294	32%	0.318	S	S	.	.			trans	-123	151.5	179	57.9	0	0	0	0	110.5	H379 P381	T316-H379 PolarHBondContact N-O 3Å; T316-P381 HydrophobicContact CG2-CG 3.8Å; T316-P381 WeakPolarHBondContact OG1-CD 3.34Å; T316-P381 WeakPolarHBondContact OG1-CG 3.49Å
317	S	86.8	Confident	84.3	Confident	16 Å²	16	56.4 Å²	56.4	11%	0.112	33%	0.328	C	S	.	.			trans	-62.9	136.1	175.4	178.5	0	0	0	0	110.8	T319 W324 D393	S317-T319 VanDerWaalsContact C-N 3.27Å; S317-T319 PolarHBondContact OG-N 2.98Å; S317-W324 VanDerWaalsContact OG-CD1 3.32Å; S317-W324 PolarHBondContact OG-NE1 3.31Å; S317-D393 WeakPolarHBondContact CB-OD2 3.27Å; S317-D393 PolarHBondContact OG-OD2 2.83Å
318	S	79.2	Confident	84.2	Confident	59 Å²	59	56.4 Å²	56.4	41%	0.413	33%	0.328	S	S	.	.			trans	-78	-12	172.7	58.4	0	0	0	0	113.4	P391 D393	S318-P391 WeakPolarHBondContact CB-O 3.49Å; S318-P391 PolarHBondContact OG-O 2.72Å; S318-D393 WeakPolarHBondContact CB-OD1 3.46Å; S318-D393 PolarHBondContact N-OD1 3.43Å; S318-D393 PolarHBondContact OG-OD1 3.27Å
319	T	76.6	Confident	84	Confident	88 Å²	88	57 Å²	57	54%	0.54	33%	0.332	S	S	.	.	S	Bend	trans	-82.7	142.2	-178.6	-48.1	0	0	0	0	110.2	S317	S317-T319 VanDerWaalsContact C-N 3.27Å; S317-T319 PolarHBondContact OG-N 2.98Å
320	S	59	Low	84.1	Confident	95 Å²	95	55.1 Å²	55.1	66%	0.664	32%	0.32	S	S	*	.			trans	-32.1	142.1	-171.9	-177.1	0	0	0	0	115.9	G322	S320-G322 PolarHBondContact O-N 2.9Å
321	P	69.6	Low	84.4	Confident	123 Å²	123	56.3 Å²	56.3	80%	0.799	32%	0.321	S	S	*	.	S	Bend	trans	-54.2	130.4	179.3	22.3	-34	0	0	0	111.8
322	G	75.2	Confident	84.6	Confident	41 Å²	41	56.6 Å²	56.6	42%	0.423	32%	0.323	S	S	.	.	S	Bend	trans	178.2	-173.6	-177.4	0	0	0	0	0	111.3	S320 W324 S325	S320-G322 PolarHBondContact O-N 2.9Å; G322-W324 PolarHBondContact O-N 3.23Å; G322-W324 VanDerWaalsContact O-N 3.08Å; G322-S325 PolarHBondContact O-N 3.15Å; G322-S325 VanDerWaalsContact O-N 3.15Å; G322-S325 PolarHBondContact O-OG 3.47Å
323	K	80.2	Confident	84.6	Confident	171 Å²	171	56.6 Å²	56.6	74%	0.743	32%	0.323	S	S	*	.	H	α-helix	trans	-55.4	-30	179.3	-68.1	-176.3	178.5	-179.5	0	112.8	S325 Q326 F327	K323-S325 VanDerWaalsContact C-N 3.3Å; K323-S325 PolarHBondContact O-N 3.08Å; K323-Q326 WeakPolarHBondContact O-CB 3.05Å; K323-Q326 PolarHBondContact O-N 3.44Å; K323-F327 VanDerWaalsContact O-CD2 3.31Å; K323-F327 WeakPolarHBondContact O-CD2 3.43Å; K323-F327 PolarHBondContact O-N 3.37Å
324	W	86.1	Confident	84.8	Confident	107 Å²	107	57.4 Å²	57.4	41%	0.405	32%	0.321	S	S	.	.	H	α-helix	trans	-57.1	-37.9	178.7	179.5	-117.7	0	0	0	113.5	S317 G322 Q326 F327 F328 I331	S317-W324 VanDerWaalsContact OG-CD1 3.32Å; S317-W324 PolarHBondContact OG-NE1 3.31Å; G322-W324 PolarHBondContact O-N 3.23Å; G322-W324 VanDerWaalsContact O-N 3.08Å; W324-Q326 PolarHBondContact O-N 3.17Å; W324-F327 PolarHBondContact O-N 2.82Å; W324-F327 VanDerWaalsContact O-N 3.13Å; W324-F328 AromaticContact CE2-CD2 3.91Å; W324-F328 AromaticContact CZ2-CD2 3.79Å; W324-F328 HydrophobicContact CZ2-CD2 3.79Å; W324-F328 AromaticContact NE1-CD2 3.8Å; W324-F328 WeakPolarHBondContact O-CB 3.3Å; W324-F328 PolarHBondContact O-N 3.22Å; W324-I331 HydrophobicContact CZ3-CD1 3.97Å
325	S	83.3	Confident	85.2	Confident	61 Å²	61	55.6 Å²	55.6	43%	0.427	31%	0.313	S	S	.	.	H	α-helix	trans	-63.7	-29.2	-179	65.7	0	0	0	0	112.8	G322 K323	G322-S325 PolarHBondContact O-N 3.15Å; G322-S325 VanDerWaalsContact O-N 3.15Å; G322-S325 PolarHBondContact O-OG 3.47Å; K323-S325 VanDerWaalsContact C-N 3.3Å; K323-S325 PolarHBondContact O-N 3.08Å
326	Q	83.3	Confident	85.6	Confident	125 Å²	125	57 Å²	57	58%	0.584	32%	0.32	S	S	*	.	H	α-helix	trans	-74.6	-36	176.5	-61.6	179.2	-7.1	0	0	112.1	M182 K323 W324 P330	M182-Q326 WeakPolarHBondContact CE-O 3.44Å; K323-Q326 WeakPolarHBondContact O-CB 3.05Å; K323-Q326 PolarHBondContact O-N 3.44Å; W324-Q326 PolarHBondContact O-N 3.17Å; Q326-P330 WeakPolarHBondContact O-CD 3.42Å
327	F	89.3	Confident	86.2	Confident	51 Å²	51	55.3 Å²	55.3	22%	0.224	31%	0.309	C	S	.	.	H	α-helix	trans	-91	-15.1	-178.6	-70.1	-77.5	0	0	0	113.8	L179 M182 K323 W324 N329 P330 I331	L179-F327 HydrophobicContact CD2-CD1 3.98Å; M182-F327 HydrophobicContact CB-CE1 4.04Å; K323-F327 VanDerWaalsContact O-CD2 3.31Å; K323-F327 WeakPolarHBondContact O-CD2 3.43Å; K323-F327 PolarHBondContact O-N 3.37Å; W324-F327 PolarHBondContact O-N 2.82Å; W324-F327 VanDerWaalsContact O-N 3.13Å; F327-N329 PolarHBondContact O-N 3.46Å; F327-P330 WeakPolarHBondContact O-CD 3.42Å; F327-I331 HydrophobicContact CB-CD1 3.86Å; F327-I331 HydrophobicContact CB-CG1 4.43Å; F327-I331 WeakPolarHBondContact O-CB 3.12Å; F327-I331 VanDerWaalsContact O-CG1 3.27Å; F327-I331 WeakPolarHBondContact O-CG1 3.48Å; F327-I331 PolarHBondContact O-N 3.13Å
328	F	91.2	Very high	86.7	Confident	1 Å²	1	55.7 Å²	55.7	0%	0.004	31%	0.309	C	S	.	.	H	α-helix	trans	-54.4	-52.8	-177.9	178.3	-98.7	0	0	0	112.4	V315 W324 I331 C332 D393 F396	V315-F328 HydrophobicContact CG1-CE1 4.25Å; W324-F328 AromaticContact CE2-CD2 3.91Å; W324-F328 AromaticContact CZ2-CD2 3.79Å; W324-F328 HydrophobicContact CZ2-CD2 3.79Å; W324-F328 AromaticContact NE1-CD2 3.8Å; W324-F328 WeakPolarHBondContact O-CB 3.3Å; W324-F328 PolarHBondContact O-N 3.22Å; F328-I331 PolarHBondContact O-N 2.93Å; F328-C332 HydrophobicContact CD2-CB 4.19Å; F328-C332 HydrophobicContact CE2-CB 3.98Å; F328-C332 HydrophobicContact CZ-CB 4.23Å; F328-C332 WeakPolarHBondContact O-CA 3.22Å; F328-C332 VanDerWaalsContact O-CB 3.26Å; F328-C332 WeakPolarHBondContact O-CB 3.4Å; F328-C332 PolarHBondContact O-N 3.4Å; F328-D393 HydrophobicContact CE2-CB 4.04Å; F328-F396 HydrophobicContact CE1-CD1 4.08Å; F328-F396 HydrophobicContact CE1-CE1 4.13Å; F328-F396 AromaticContact CZ-CD1 3.65Å; F328-F396 HydrophobicContact CZ-CD1 3.65Å; F328-F396 HydrophobicContact CZ-CE1 4.1Å; F328-F396 HydrophobicContact CZ-CG 4.4Å
329	N	90.4	Very high	87.6	Confident	32 Å²	32	55.6 Å²	55.6	17%	0.171	30%	0.303	C	S	.	.	I	π-helix	trans	-65	-51	179.7	-84.6	-35.7	0	0	0	112.8	A313 V315 F327 I331 C333 F334	A313-N329 PolarHBondContact O-ND2 3.41Å; V315-N329 PolarHBondContact O-ND2 3.4Å; V315-N329 PolarHBondContact O-OD1 2.82Å; V315-N329 VanDerWaalsContact O-OD1 3.1Å; F327-N329 PolarHBondContact O-N 3.46Å; N329-I331 VanDerWaalsContact C-N 3.27Å; N329-I331 PolarHBondContact O-N 3.33Å; N329-C333 WeakPolarHBondContact O-CA 3.24Å; N329-C333 WeakPolarHBondContact O-CB 3.34Å; N329-C333 PolarHBondContact O-N 3.28Å; N329-F334 PolarHBondContact O-N 2.94Å; N329-F334 VanDerWaalsContact O-N 3.1Å
330	P	91.9	Very high	88.6	Confident	9 Å²	9	53 Å²	53	6%	0.058	29%	0.286	C	S	.	.	I	π-helix	trans	-50.3	-41.9	172.8	-33.2	38	0	0	0	114.8	M178 L179 M182 Q326 F327 L335	M178-P330 HydrophobicContact CE-CB 3.82Å; M178-P330 HydrophobicContact CE-CG 4.29Å; L179-P330 HydrophobicContact CD2-CB 3.44Å; L179-P330 VanDerWaalsContact CD2-CB 3.44Å; L179-P330 HydrophobicContact CG-CB 4.14Å; M182-P330 HydrophobicContact CE-CG 3.98Å; M182-P330 HydrophobicContact SD-CB 4.33Å; M182-P330 HydrophobicContact SD-CG 3.58Å; M182-P330 VanDerWaalsContact SD-CG 3.58Å; Q326-P330 WeakPolarHBondContact O-CD 3.42Å; F327-P330 WeakPolarHBondContact O-CD 3.42Å; P330-L335 WeakPolarHBondContact O-CB 3.42Å; P330-L335 PolarHBondContact O-N 3.3Å
331	I	93.9	Very high	90.4	Very high	58 Å²	58	48.9 Å²	48.9	30%	0.297	26%	0.256	S	S	.	.	I	π-helix	trans	-84.1	-60	-176.4	-62.9	174.6	0	0	0	111.5	L179 W324 F327 F328 N329 L335 L336	L179-I331 HydrophobicContact CD1-CG1 4.3Å; L179-I331 HydrophobicContact CD2-CG1 3.78Å; W324-I331 HydrophobicContact CZ3-CD1 3.97Å; F327-I331 HydrophobicContact CB-CD1 3.86Å; F327-I331 HydrophobicContact CB-CG1 4.43Å; F327-I331 WeakPolarHBondContact O-CB 3.12Å; F327-I331 VanDerWaalsContact O-CG1 3.27Å; F327-I331 WeakPolarHBondContact O-CG1 3.48Å; F327-I331 PolarHBondContact O-N 3.13Å; F328-I331 PolarHBondContact O-N 2.93Å; N329-I331 VanDerWaalsContact C-N 3.27Å; N329-I331 PolarHBondContact O-N 3.33Å; I331-L335 WeakPolarHBondContact O-CB 3.42Å; I331-L336 WeakPolarHBondContact O-CB 3.13Å; I331-L336 PolarHBondContact O-N 3.41Å
332	C	94.4	Very high	91.7	Very high	7 Å²	7	47 Å²	47	5%	0.047	23%	0.233	C	C	.	.	I	π-helix	trans	-81.2	-24.3	-169.5	-61.9	0	0	0	0	113.4	F328 L336 F396 I397	F328-C332 HydrophobicContact CD2-CB 4.19Å; F328-C332 HydrophobicContact CE2-CB 3.98Å; F328-C332 HydrophobicContact CZ-CB 4.23Å; F328-C332 WeakPolarHBondContact O-CA 3.22Å; F328-C332 VanDerWaalsContact O-CB 3.26Å; F328-C332 WeakPolarHBondContact O-CB 3.4Å; F328-C332 PolarHBondContact O-N 3.4Å; C332-L336 WeakPolarHBondContact O-CB 3.39Å; C332-F396 HydrophobicContact CB-CD1 4.37Å; C332-F396 HydrophobicContact CB-CE1 4.12Å; C332-I397 HydrophobicContact CB-CG1 4.16Å
333	C	93.2	Very high	92.8	Very high	0 Å²	0	48.8 Å²	48.8	0%	0	23%	0.232	C	C	.	.	I	π-helix	trans	-95.7	-65.1	175.4	-172.9	0	0	0	0	110.4	T312 N329 F337 F396	T312-C333 PolarHBondContact OG1-SG 2.7Å; N329-C333 WeakPolarHBondContact O-CA 3.24Å; N329-C333 WeakPolarHBondContact O-CB 3.34Å; N329-C333 PolarHBondContact O-N 3.28Å; C333-F337 WeakPolarHBondContact O-CB 3.45Å; C333-F337 PolarHBondContact O-N 3.3Å; C333-F396 HydrophobicContact CB-CE1 4.29Å; C333-F396 HydrophobicContact CB-CZ 4.02Å
334	F	94.3	Very high	93.6	Very high	48 Å²	48	40.6 Å²	40.6	21%	0.211	20%	0.197	C	C	.	.	I	π-helix	trans	-77.3	-54.8	-170.7	-66.6	-75.8	0	0	0	113.6	A175 M178 F308 P309 A313 N329 F337 N338	A175-F334 HydrophobicContact CB-CB 4.46Å; M178-F334 HydrophobicContact CE-CB 3.72Å; M178-F334 HydrophobicContact CE-CD2 3.73Å; M178-F334 HydrophobicContact CE-CG 3.86Å; M178-F334 HydrophobicContact SD-CD2 4.49Å; F308-F334 HydrophobicContact CE2-CD1 4.17Å; F308-F334 HydrophobicContact CE2-CE1 4.48Å; F308-F334 AromaticContact CZ-CD1 3.9Å; F308-F334 HydrophobicContact CZ-CD1 3.9Å; F308-F334 HydrophobicContact CZ-CE1 4.28Å; P309-F334 HydrophobicContact CB-CE1 3.65Å; P309-F334 HydrophobicContact CB-CZ 3.88Å; P309-F334 HydrophobicContact CG-CE1 4.34Å; A313-F334 HydrophobicContact CB-CE2 4.38Å; A313-F334 HydrophobicContact CB-CZ 4.23Å; N329-F334 PolarHBondContact O-N 2.94Å; N329-F334 VanDerWaalsContact O-N 3.1Å; F334-F337 PolarHBondContact O-N 2.79Å; F334-N338 WeakPolarHBondContact O-CB 3.5Å; F334-N338 PolarHBondContact O-N 3.11Å; F334-N338 PolarHBondContact O-ND2 3.22Å
335	L	96.6	Very high	94	Very high	26 Å²	26	36.1 Å²	36.1	14%	0.136	18%	0.18	C	C	.	.	I	π-helix	trans	-64.6	-47.4	-177.2	-178.4	67.1	0	0	0	111.1	I172 A175 L176 L179 P330 I331 F337 N338 I339	I172-L335 HydrophobicContact CG2-CD1 4.48Å; A175-L335 HydrophobicContact CB-CB 4.17Å; A175-L335 HydrophobicContact CB-CD1 3.99Å; L176-L335 HydrophobicContact CD2-CD1 3.88Å; L176-L335 HydrophobicContact CG-CD1 4.12Å; L179-L335 HydrophobicContact CD1-CB 4.32Å; L179-L335 HydrophobicContact CD1-CD2 3.75Å; L179-L335 HydrophobicContact CD1-CG 4.47Å; P330-L335 WeakPolarHBondContact O-CB 3.42Å; P330-L335 PolarHBondContact O-N 3.3Å; I331-L335 WeakPolarHBondContact O-CB 3.42Å; L335-F337 PolarHBondContact O-N 3.03Å; L335-N338 PolarHBondContact O-N 3.02Å; L335-I339 HydrophobicContact CD1-CD1 3.85Å; L335-I339 HydrophobicContact CD1-CG1 4.12Å; L335-I339 HydrophobicContact CD2-CD1 4.29Å; L335-I339 HydrophobicContact CG-CD1 3.72Å; L335-I339 HydrophobicContact CG-CG1 4.32Å; L335-I339 WeakPolarHBondContact O-CG1 3.46Å; L335-I339 PolarHBondContact O-N 3.48Å
336	L	97.4	Very high	94.5	Very high	32 Å²	32	34.2 Å²	34.2	17%	0.168	17%	0.166	C	C	.	.	H	α-helix	trans	-60.4	-44.2	178.8	-177	61.6	0	0	0	112.1	I331 C332 N338 M340 I397 M400	I331-L336 WeakPolarHBondContact O-CB 3.13Å; I331-L336 PolarHBondContact O-N 3.41Å; C332-L336 WeakPolarHBondContact O-CB 3.39Å; L336-N338 PolarHBondContact O-N 2.93Å; L336-M340 HydrophobicContact CD1-CE 4.37Å; L336-M340 HydrophobicContact CD1-CG 3.93Å; L336-M340 WeakPolarHBondContact O-CB 3.4Å; L336-M340 WeakPolarHBondContact O-CG 3.24Å; L336-M340 PolarHBondContact O-N 3.44Å; L336-I397 HydrophobicContact CD2-CG2 3.88Å; L336-M400 HydrophobicContact CD2-CB 3.95Å
337	F	97.5	Very high	95	Very high	12 Å²	12	31.5 Å²	31.5	5%	0.053	16%	0.156	C	C	.	.	H	α-helix	trans	-57.8	-50.5	174.8	179.3	-93.4	0	0	0	111.1	T304 F308 C333 F334 L335 I339 M340 D341 M400 F403 A404	T304-F337 HydrophobicContact CG2-CE2 4.02Å; T304-F337 HydrophobicContact CG2-CZ 3.82Å; F308-F337 HydrophobicContact CD1-CD1 4.14Å; F308-F337 HydrophobicContact CD1-CD2 4.38Å; F308-F337 AromaticContact CD1-CE1 3.94Å; F308-F337 HydrophobicContact CD1-CE1 3.94Å; F308-F337 HydrophobicContact CD1-CE2 4.18Å; F308-F337 HydrophobicContact CD1-CG 4.36Å; F308-F337 AromaticContact CD1-CZ 3.96Å; F308-F337 HydrophobicContact CD1-CZ 3.96Å; F308-F337 HydrophobicContact CD2-CB 4.39Å; F308-F337 HydrophobicContact CD2-CD2 4.14Å; F308-F337 HydrophobicContact CD2-CG 4.13Å; F308-F337 AromaticContact CE1-CD1 3.53Å; F308-F337 HydrophobicContact CE1-CD1 3.53Å; F308-F337 HydrophobicContact CE1-CD2 4.47Å; F308-F337 AromaticContact CE1-CE1 3.58Å; F308-F337 HydrophobicContact CE1-CE1 3.58Å; F308-F337 HydrophobicContact CE1-CG 4Å; F308-F337 HydrophobicContact CE1-CZ 4.09Å; F308-F337 HydrophobicContact CE2-CB 3.76Å; F308-F337 HydrophobicContact CE2-CD1 4.06Å; F308-F337 HydrophobicContact CE2-CD2 4.24Å; F308-F337 AromaticContact CE2-CG 3.75Å; F308-F337 HydrophobicContact CE2-CG 3.75Å; F308-F337 HydrophobicContact CG-CD2 4.22Å; F308-F337 HydrophobicContact CG-CE2 4.24Å; F308-F337 HydrophobicContact CG-CG 4.42Å; F308-F337 HydrophobicContact CG-CZ 4.48Å; F308-F337 HydrophobicContact CZ-CB 3.96Å; F308-F337 AromaticContact CZ-CD1 3.48Å; F308-F337 HydrophobicContact CZ-CD1 3.48Å; F308-F337 VanDerWaalsContact CZ-CD1 3.48Å; F308-F337 HydrophobicContact CZ-CD2 4.41Å; F308-F337 HydrophobicContact CZ-CE1 4.05Å; F308-F337 AromaticContact CZ-CG 3.68Å; F308-F337 HydrophobicContact CZ-CG 3.68Å; C333-F337 WeakPolarHBondContact O-CB 3.45Å; C333-F337 PolarHBondContact O-N 3.3Å; F334-F337 PolarHBondContact O-N 2.79Å; L335-F337 PolarHBondContact O-N 3.03Å; F337-I339 PolarHBondContact O-N 3.42Å; F337-M340 PolarHBondContact O-N 3.37Å; F337-D341 HydrophobicContact CE1-CB 4.31Å; F337-D341 WeakPolarHBondContact O-CB 3.36Å; F337-D341 PolarHBondContact O-N 2.95Å; F337-M400 HydrophobicContact CB-CE 3.7Å; F337-M400 HydrophobicContact CD2-CE 3.54Å; F337-M400 HydrophobicContact CG-CE 4.07Å; F337-F403 HydrophobicContact CD2-CD1 4.03Å; F337-F403 HydrophobicContact CD2-CE1 4.01Å; F337-F403 AromaticContact CE2-CD1 3.92Å; F337-F403 HydrophobicContact CE2-CD1 3.92Å; F337-F403 AromaticContact CE2-CE1 3.63Å; F337-F403 HydrophobicContact CE2-CE1 3.63Å; F337-A404 HydrophobicContact CB-CB 4.36Å; F337-A404 HydrophobicContact CD2-CB 3.57Å; F337-A404 HydrophobicContact CE2-CB 4.11Å; F337-A404 HydrophobicContact CG-CB 4.13Å; F337-A404 WeakPolarHBondContact O-CB 3.48Å
338	N	97.6	Very high	95	Very high	23 Å²	23	29.1 Å²	29.1	12%	0.123	15%	0.145	C	C	.	.	H	α-helix	trans	-66.9	-38	-175.6	-75	-67.3	0	0	0	113.1	G171 I172 F334 L335 L336 W342	G171-N338 WeakPolarHBondContact CA-OD1 3.31Å; I172-N338 HydrophobicContact CG1-CB 4Å; F334-N338 WeakPolarHBondContact O-CB 3.5Å; F334-N338 PolarHBondContact O-N 3.11Å; F334-N338 PolarHBondContact O-ND2 3.22Å; L335-N338 PolarHBondContact O-N 3.02Å; L336-N338 PolarHBondContact O-N 2.93Å; N338-W342 VanDerWaalsContact O-CB 3.24Å; N338-W342 WeakPolarHBondContact O-CB 3.32Å; N338-W342 PolarHBondContact O-N 3.5Å
339	I	98.1	Very high	94.8	Very high	57 Å²	57	30.9 Å²	30.9	29%	0.292	16%	0.158	S	C	.	.	H	α-helix	trans	-65.3	-46.5	176.1	-65.6	173	0	0	0	110.5	I172 L335 F337 W342 L343	I172-I339 HydrophobicContact CD1-CG1 4.15Å; I172-I339 HydrophobicContact CG1-CG1 4.15Å; L335-I339 HydrophobicContact CD1-CD1 3.85Å; L335-I339 HydrophobicContact CD1-CG1 4.12Å; L335-I339 HydrophobicContact CD2-CD1 4.29Å; L335-I339 HydrophobicContact CG-CD1 3.72Å; L335-I339 HydrophobicContact CG-CG1 4.32Å; L335-I339 WeakPolarHBondContact O-CG1 3.46Å; L335-I339 PolarHBondContact O-N 3.48Å; F337-I339 PolarHBondContact O-N 3.42Å; I339-W342 PolarHBondContact O-N 3.31Å; I339-L343 WeakPolarHBondContact O-CB 3.45Å; I339-L343 PolarHBondContact O-N 2.67Å
340	M	98.1	Very high	94.6	Very high	34 Å²	34	38.1 Å²	38.1	17%	0.167	18%	0.184	C	C	.	.	H	α-helix	trans	-73	-36.5	-177.1	-68.2	-61	130.7	0	0	112.2	L336 F337 L343 G344 L401 A404 I405	L336-M340 HydrophobicContact CD1-CE 4.37Å; L336-M340 HydrophobicContact CD1-CG 3.93Å; L336-M340 WeakPolarHBondContact O-CB 3.4Å; L336-M340 WeakPolarHBondContact O-CG 3.24Å; L336-M340 PolarHBondContact O-N 3.44Å; F337-M340 PolarHBondContact O-N 3.37Å; M340-L343 PolarHBondContact O-N 3.5Å; M340-L343 HydrophobicContact SD-CD2 4.23Å; M340-G344 PolarHBondContact O-N 3.47Å; M340-L401 HydrophobicContact CG-CG 4.13Å; M340-L401 HydrophobicContact SD-CD1 4.45Å; M340-L401 HydrophobicContact SD-CG 3.94Å; M340-A404 HydrophobicContact CB-CB 3.56Å; M340-I405 HydrophobicContact CB-CB 4.35Å; M340-I405 WeakPolarHBondContact O-CA 3.47Å
341	D	97.9	Very high	94.4	Very high	8 Å²	8	44.1 Å²	44.1	4%	0.043	21%	0.209	C	C	.	.	H	α-helix	trans	-60.6	-48.1	171.1	-175.4	70.7	0	0	0	110.7	F337 L343 G344 R345 A404 N407 G408	F337-D341 HydrophobicContact CE1-CB 4.31Å; F337-D341 WeakPolarHBondContact O-CB 3.36Å; F337-D341 PolarHBondContact O-N 2.95Å; D341-L343 VanDerWaalsContact C-N 3.34Å; D341-L343 PolarHBondContact O-N 2.95Å; D341-G344 PolarHBondContact O-N 2.64Å; D341-R345 VanDerWaalsContact O-CG 3.29Å; D341-R345 WeakPolarHBondContact O-CG 3.38Å; D341-R345 PolarHBondContact O-N 2.88Å; D341-R345 IonicContact OD1-NE 3.74Å; D341-R345 IonicContact OD2-CZ 3.61Å; D341-R345 IonicContact OD2-NE 2.77Å; D341-R345 PolarHBondContact OD2-NE 3.18Å; D341-R345 IonicContact OD2-NH2 3.57Å; D341-A404 WeakPolarHBondContact CA-O 3.31Å; D341-N407 PolarHBondContact OD1-ND2 3.28Å; D341-G408 WeakPolarHBondContact O-CA 2.89Å; D341-G408 WeakPolarHBondContact OD1-CA 3.45Å; D341-G408 PolarHBondContact OD1-N 3.4Å
342	W	97.1	Very high	94.1	Very high	85 Å²	85	43.9 Å²	43.9	32%	0.322	21%	0.208	S	C	.	.	H	α-helix	trans	-59.1	-43.1	174.5	170.7	66.7	0	0	0	112.7	S165 I172 N338 I339 R345 S346	S165-W342 VanDerWaalsContact O-CD1 3.24Å; S165-W342 PolarHBondContact OG-NE1 2.92Å; S165-W342 VanDerWaalsContact OG-NE1 3.08Å; I172-W342 HydrophobicContact CD1-CB 3.75Å; I172-W342 HydrophobicContact CD1-CD2 3.88Å; I172-W342 HydrophobicContact CD1-CE3 3.86Å; I172-W342 HydrophobicContact CD1-CG 3.84Å; I172-W342 HydrophobicContact CG1-CB 4.46Å; N338-W342 VanDerWaalsContact O-CB 3.24Å; N338-W342 WeakPolarHBondContact O-CB 3.32Å; N338-W342 PolarHBondContact O-N 3.5Å; I339-W342 PolarHBondContact O-N 3.31Å; W342-R345 PolarHBondContact O-N 3.43Å; W342-S346 PolarHBondContact NE1-OG 2.94Å; W342-S346 VanDerWaalsContact O-CB 3.31Å; W342-S346 WeakPolarHBondContact O-CB 3.42Å; W342-S346 PolarHBondContact O-N 2.88Å; W342-S346 PolarHBondContact O-OG 3.4Å
343	L	97	Very high	93.9	Very high	77 Å²	77	51 Å²	51	40%	0.403	23%	0.234	S	C	.	.	H	α-helix	trans	-61.8	-45	176.7	-177	62.1	0	0	0	111.1	I339 M340 D341 R345 S346 L347 I405	I339-L343 WeakPolarHBondContact O-CB 3.45Å; I339-L343 PolarHBondContact O-N 2.67Å; M340-L343 PolarHBondContact O-N 3.5Å; M340-L343 HydrophobicContact SD-CD2 4.23Å; D341-L343 VanDerWaalsContact C-N 3.34Å; D341-L343 PolarHBondContact O-N 2.95Å; L343-R345 PolarHBondContact O-N 3.4Å; L343-S346 PolarHBondContact O-N 2.87Å; L343-L347 WeakPolarHBondContact O-CB 3.48Å; L343-L347 PolarHBondContact O-N 2.87Å; L343-I405 HydrophobicContact CD2-CD1 4.19Å; L343-I405 HydrophobicContact CG-CD1 4.5Å
344	G	96.7	Very high	93.7	Very high	0 Å²	0	51 Å²	51	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-58.4	-46.6	175.1	0	0	0	0	0	112.3	M340 D341 S346 L347 Y409	M340-G344 PolarHBondContact O-N 3.47Å; D341-G344 PolarHBondContact O-N 2.64Å; G344-S346 VanDerWaalsContact C-N 3.3Å; G344-S346 PolarHBondContact O-N 3.13Å; G344-L347 PolarHBondContact O-N 3.42Å; G344-Y409 WeakPolarHBondContact O-CA 3.48Å; G344-Y409 WeakPolarHBondContact O-CD2 3.26Å
345	R	95.1	Very high	93.2	Very high	13 Å²	13	53.5 Å²	53.5	5%	0.049	25%	0.25	C	C	.	.	H	α-helix	trans	-65.4	-32.5	176.9	-66.3	174.9	-179.2	-97.4	-0.9	113.2	L164 D341 W342 L343 T348 G408 S412	L164-R345 VanDerWaalsContact CD2-NH1 3.31Å; L164-R345 VanDerWaalsContact O-CD 3.25Å; L164-R345 WeakPolarHBondContact O-CD 3.47Å; D341-R345 VanDerWaalsContact O-CG 3.29Å; D341-R345 WeakPolarHBondContact O-CG 3.38Å; D341-R345 PolarHBondContact O-N 2.88Å; D341-R345 IonicContact OD1-NE 3.74Å; D341-R345 IonicContact OD2-CZ 3.61Å; D341-R345 IonicContact OD2-NE 2.77Å; D341-R345 PolarHBondContact OD2-NE 3.18Å; D341-R345 IonicContact OD2-NH2 3.57Å; W342-R345 PolarHBondContact O-N 3.43Å; L343-R345 PolarHBondContact O-N 3.4Å; R345-T348 PolarHBondContact O-OG1 3.33Å; R345-G408 WeakPolarHBondContact CG-O 3.47Å; R345-S412 WeakPolarHBondContact CA-OG 3.25Å; R345-S412 WeakPolarHBondContact CB-OG 3.34Å; R345-S412 WeakPolarHBondContact CG-OG 3.11Å
346	S	93.4	Very high	92.2	Very high	20 Å²	20	54.2 Å²	54.2	14%	0.14	25%	0.253	C	S	.	.	H	α-helix	trans	-77.1	-34.7	179.8	-58.1	0	0	0	0	111.2	S165 W342 L343 G344 T348 S349	S165-S346 PolarHBondContact OG-OG 2.93Å; W342-S346 PolarHBondContact NE1-OG 2.94Å; W342-S346 VanDerWaalsContact O-CB 3.31Å; W342-S346 WeakPolarHBondContact O-CB 3.42Å; W342-S346 PolarHBondContact O-N 2.88Å; W342-S346 PolarHBondContact O-OG 3.4Å; L343-S346 PolarHBondContact O-N 2.87Å; G344-S346 VanDerWaalsContact C-N 3.3Å; G344-S346 PolarHBondContact O-N 3.13Å; S346-T348 PolarHBondContact O-N 2.95Å; S346-S349 VanDerWaalsContact O-CB 3.24Å; S346-S349 WeakPolarHBondContact O-CB 3.44Å; S346-S349 PolarHBondContact O-N 3.38Å; S346-S349 PolarHBondContact O-OG 2.94Å
347	L	93.3	Very high	91.2	Very high	69 Å²	69	60.3 Å²	60.3	36%	0.361	29%	0.285	S	S	.	.	H	α-helix	trans	-60.7	-33.1	178.4	-172.8	64.2	0	0	0	112.5	L343 G344 S349 Y350 F351 Y409	L343-L347 WeakPolarHBondContact O-CB 3.48Å; L343-L347 PolarHBondContact O-N 2.87Å; G344-L347 PolarHBondContact O-N 3.42Å; L347-S349 PolarHBondContact O-N 3.47Å; L347-S349 VanDerWaalsContact O-N 3.16Å; L347-Y350 PolarHBondContact O-N 3.48Å; L347-F351 HydrophobicContact CD1-CD2 3.81Å; L347-F351 HydrophobicContact CD1-CE2 4.35Å; L347-F351 HydrophobicContact CG-CD2 4.5Å; L347-F351 PolarHBondContact O-N 3.47Å; L347-Y409 HydrophobicContact CB-CD2 4.08Å; L347-Y409 HydrophobicContact CB-CE2 4.26Å; L347-Y409 HydrophobicContact CD2-CD2 3.97Å; L347-Y409 HydrophobicContact CD2-CE2 3.96Å; L347-Y409 HydrophobicContact CG-CD2 4.19Å; L347-Y409 HydrophobicContact CG-CE2 3.99Å
348	T	90.6	Very high	90.6	Very high	0 Å²	0	62 Å²	62	0%	0	30%	0.298	C	S	.	.	T	Hydrogen-bonded Turn	trans	-65	-15.5	175.1	55.8	0	0	0	0	113.6	R345 S346 Y350 L352 Y409 S412 L413	R345-T348 PolarHBondContact O-OG1 3.33Å; S346-T348 PolarHBondContact O-N 2.95Å; T348-Y350 PolarHBondContact O-N 3.39Å; T348-L352 WeakPolarHBondContact O-CD1 3.28Å; T348-Y409 HydrophobicContact CG2-CD2 3.48Å; T348-Y409 VanDerWaalsContact CG2-CD2 3.48Å; T348-Y409 HydrophobicContact CG2-CE2 3.53Å; T348-Y409 HydrophobicContact CG2-CG 4.13Å; T348-Y409 WeakPolarHBondContact CG2-O 3.3Å; T348-S412 WeakPolarHBondContact OG1-CB 3.33Å; T348-L413 HydrophobicContact CG2-CB 4.3Å
349	S	86.8	Confident	90.1	Very high	38 Å²	38	71.8 Å²	71.8	27%	0.266	33%	0.334	S	S	.	.	T	Hydrogen-bonded Turn	trans	-70.7	-23.1	172.1	-54.8	0	0	0	0	112.7	T161 S346 L347	T161-S349 VanDerWaalsContact CB-OG 3.27Å; T161-S349 WeakPolarHBondContact CB-OG 3.47Å; T161-S349 WeakPolarHBondContact OG1-CB 3.09Å; T161-S349 PolarHBondContact OG1-OG 2.93Å; S346-S349 VanDerWaalsContact O-CB 3.24Å; S346-S349 WeakPolarHBondContact O-CB 3.44Å; S346-S349 PolarHBondContact O-N 3.38Å; S346-S349 PolarHBondContact O-OG 2.94Å; L347-S349 PolarHBondContact O-N 3.47Å; L347-S349 VanDerWaalsContact O-N 3.16Å
350	Y	86.6	Confident	89.9	Confident	185 Å²	185	71.4 Å²	71.4	73%	0.725	33%	0.332	S	S	*	.	T	Hydrogen-bonded Turn	trans	-105.2	-38.1	-179.4	-60	-80.3	0	0	0	112.1	L347 T348	L347-Y350 PolarHBondContact O-N 3.48Å; T348-Y350 PolarHBondContact O-N 3.39Å
351	F	87.6	Confident	89.7	Confident	135 Å²	135	70.1 Å²	70.1	59%	0.592	33%	0.326	S	S	*	.			trans	-134.1	105.9	-174.5	-57.1	-78.6	0	0	0	111.2	L347 Y409	L347-F351 HydrophobicContact CD1-CD2 3.81Å; L347-F351 HydrophobicContact CD1-CE2 4.35Å; L347-F351 HydrophobicContact CG-CD2 4.5Å; L347-F351 PolarHBondContact O-N 3.47Å; F351-Y409 PolarHBondContact O-OH 3Å
352	L	87.3	Confident	89.5	Confident	52 Å²	52	71.3 Å²	71.3	27%	0.272	33%	0.334	S	S	.	.			trans	-94.4	91.4	167.5	-75.1	88.3	0	0	0	108.7	T348 L413 C416 L417	T348-L352 WeakPolarHBondContact O-CD1 3.28Å; L352-L413 HydrophobicContact CB-CD1 4.11Å; L352-L413 HydrophobicContact CG-CD1 4.38Å; L352-C416 HydrophobicContact CD2-CB 3.97Å; L352-L417 HydrophobicContact CD2-CD2 4.34Å
353	W	89.7	Confident	89.4	Confident	157 Å²	157	72.6 Å²	72.6	60%	0.595	35%	0.347	S	S	*	.			trans	-143	143.2	176.6	178.2	91.3	0	0	0	109.4	L360 Y409 L413	W353-L360 HydrophobicContact CH2-CD2 3.18Å; W353-L360 HydrophobicContact CH2-CG 4.48Å; W353-L360 HydrophobicContact CZ2-CD2 3.27Å; W353-L360 HydrophobicContact CZ3-CD2 3.93Å; W353-Y409 PolarHBondContact N-OH 3.39Å; W353-Y409 WeakPolarHBondContact O-CE1 3.2Å; W353-Y409 PolarHBondContact O-OH 2.89Å; W353-L413 WeakPolarHBondContact O-CD2 3.47Å
354	P	89	Confident	89.3	Confident	0 Å²	0	71.6 Å²	71.6	0%	0	34%	0.341	C	S	.	.	S	Bend	cis	-73.1	164.3	-3.5	31.4	-37	0	0	0	113.4	L360 L361 L364	P354-L360 HydrophobicContact CB-CB 3.99Å; P354-L360 HydrophobicContact CB-CD2 4.09Å; P354-L360 HydrophobicContact CB-CG 4.33Å; P354-L360 HydrophobicContact CG-CB 3.94Å; P354-L360 HydrophobicContact CG-CD2 4.26Å; P354-L360 HydrophobicContact CG-CG 4.1Å; P354-L361 HydrophobicContact CG-CB 3.97Å; P354-L364 HydrophobicContact CG-CD1 4.49Å
355	D	83.4	Confident	89.3	Confident	101 Å²	101	71.6 Å²	71.6	54%	0.54	34%	0.341	S	S	.	.			trans	-73.2	168.4	-179.2	-149.1	-7.8	0	0	0	112.6	D357 S358	D355-D357 VanDerWaalsContact C-N 3.29Å; D355-D357 PolarHBondContact O-N 2.93Å; D355-S358 VanDerWaalsContact O-CB 3.26Å; D355-S358 WeakPolarHBondContact O-CB 3.44Å; D355-S358 PolarHBondContact O-N 2.92Å
356	E	76.4	Confident	89.4	Confident	41 Å²	41	74.4 Å²	74.4	19%	0.192	36%	0.362	C	S	.	.	T	Hydrogen-bonded Turn	trans	-57.6	-36.6	-170.9	-60.2	-179.1	-164.1	0	0	113.6	S358 L417 R420 Q421	E356-S358 VanDerWaalsContact C-N 3.33Å; E356-L417 HydrophobicContact CG-CB 3.93Å; E356-L417 HydrophobicContact CG-CD1 4.2Å; E356-L417 HydrophobicContact CG-CD2 3.41Å; E356-L417 VanDerWaalsContact CG-CD2 3.41Å; E356-L417 HydrophobicContact CG-CG 3.98Å; E356-R420 WeakPolarHBondContact OE1-CB 3.21Å; E356-R420 WeakPolarHBondContact OE1-CD 3.26Å; E356-Q421 HydrophobicContact CB-CG 4.43Å; E356-Q421 WeakPolarHBondContact OE2-CG 3.27Å
357	D	77.2	Confident	89.5	Confident	160 Å²	160	78.8 Å²	78.8	86%	0.856	38%	0.384	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.2	-3.5	-178	-62.1	-42.7	0	0	0	113.6	D355 R359	D355-D357 VanDerWaalsContact C-N 3.29Å; D355-D357 PolarHBondContact O-N 2.93Å; D357-R359 PolarHBondContact O-N 3.05Å
358	S	83.6	Confident	89.7	Confident	47 Å²	47	75.7 Å²	75.7	33%	0.329	37%	0.367	S	S	.	.			trans	-80.6	126.2	-173.4	-173.9	0	0	0	0	112.2	D355 E356 L360 L361	D355-S358 VanDerWaalsContact O-CB 3.26Å; D355-S358 WeakPolarHBondContact O-CB 3.44Å; D355-S358 PolarHBondContact O-N 2.92Å; E356-S358 VanDerWaalsContact C-N 3.33Å; S358-L360 PolarHBondContact O-N 3.08Å; S358-L360 VanDerWaalsContact OG-CB 3.28Å; S358-L360 WeakPolarHBondContact OG-CB 3.18Å; S358-L360 PolarHBondContact OG-N 3.48Å; S358-L361 PolarHBondContact O-N 3.03Å
359	R	88.3	Confident	90	Very high	229 Å²	229	79.9 Å²	79.9	86%	0.864	39%	0.385	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.9	-6.9	170.5	-63.7	-171	178.8	-171.2	0.2	113.7	D357 L363	D357-R359 PolarHBondContact O-N 3.05Å; R359-L363 PolarHBondContact O-N 3.39Å
360	L	92.9	Very high	90.5	Very high	48 Å²	48	82.8 Å²	82.8	25%	0.251	40%	0.398	S	S	.	.	H	α-helix	trans	-70.1	-33.1	178.5	-173.5	58.6	0	0	0	112.7	W353 P354 S358 L363 L364	W353-L360 HydrophobicContact CH2-CD2 3.18Å; W353-L360 HydrophobicContact CH2-CG 4.48Å; W353-L360 HydrophobicContact CZ2-CD2 3.27Å; W353-L360 HydrophobicContact CZ3-CD2 3.93Å; P354-L360 HydrophobicContact CB-CB 3.99Å; P354-L360 HydrophobicContact CB-CD2 4.09Å; P354-L360 HydrophobicContact CB-CG 4.33Å; P354-L360 HydrophobicContact CG-CB 3.94Å; P354-L360 HydrophobicContact CG-CD2 4.26Å; P354-L360 HydrophobicContact CG-CG 4.1Å; S358-L360 PolarHBondContact O-N 3.08Å; S358-L360 VanDerWaalsContact OG-CB 3.28Å; S358-L360 WeakPolarHBondContact OG-CB 3.18Å; S358-L360 PolarHBondContact OG-N 3.48Å; L360-L363 HydrophobicContact CD1-CD2 4.02Å; L360-L363 PolarHBondContact O-N 3.22Å; L360-L364 HydrophobicContact CD1-CD2 4.49Å; L360-L364 HydrophobicContact CD1-CG 4.14Å; L360-L364 HydrophobicContact CG-CD1 4.04Å; L360-L364 HydrophobicContact CG-CG 4.16Å; L360-L364 WeakPolarHBondContact O-CG 3.27Å; L360-L364 PolarHBondContact O-N 3.16Å
361	L	93.3	Very high	91	Very high	7 Å²	7	75.3 Å²	75.3	4%	0.037	37%	0.369	C	S	.	.	H	α-helix	trans	-60.4	-54.8	178.9	168.2	66	0	0	0	111.6	P354 S358 L363 L364 V365 L410 L413 T414 L417	P354-L361 HydrophobicContact CG-CB 3.97Å; S358-L361 PolarHBondContact O-N 3.03Å; L361-L363 VanDerWaalsContact C-N 3.27Å; L361-L363 PolarHBondContact O-N 3.38Å; L361-L364 PolarHBondContact O-N 2.71Å; L361-V365 HydrophobicContact CD1-CG2 4.27Å; L361-V365 WeakPolarHBondContact O-CG2 3.43Å; L361-V365 PolarHBondContact O-N 3.14Å; L361-V365 VanDerWaalsContact O-N 3.09Å; L361-L410 HydrophobicContact CD1-CD2 3.84Å; L361-L413 HydrophobicContact CD1-CD2 4.13Å; L361-T414 HydrophobicContact CD1-CG2 4.13Å; L361-T414 HydrophobicContact CD2-CG2 4.1Å; L361-L417 HydrophobicContact CD2-CD1 4.28Å
362	P	94.3	Very high	91.3	Very high	34 Å²	34	69.6 Å²	69.6	22%	0.221	35%	0.345	C	S	.	.	H	α-helix	trans	-56	-39.6	173.9	-25.7	31.9	0	0	0	113.4	L292 V365 C366	L292-P362 HydrophobicContact CD1-CG 4.2Å; L292-P362 HydrophobicContact CD2-CG 4.24Å; L292-P362 HydrophobicContact CG-CG 4.36Å; P362-V365 PolarHBondContact O-N 3.26Å; P362-C366 WeakPolarHBondContact O-CB 3.32Å; P362-C366 PolarHBondContact O-N 3.18Å; P362-C366 PolarHBondContact O-SG 3.43Å
363	L	95.4	Very high	91.6	Very high	112 Å²	112	69.9 Å²	69.9	59%	0.586	35%	0.35	S	S	*	.	H	α-helix	trans	-61.8	-47.1	178.8	179.7	65.7	0	0	0	112.1	R359 L360 L361 V365 C366 L367	R359-L363 PolarHBondContact O-N 3.39Å; L360-L363 HydrophobicContact CD1-CD2 4.02Å; L360-L363 PolarHBondContact O-N 3.22Å; L361-L363 VanDerWaalsContact C-N 3.27Å; L361-L363 PolarHBondContact O-N 3.38Å; L363-V365 VanDerWaalsContact C-N 3.29Å; L363-V365 PolarHBondContact O-N 2.94Å; L363-C366 PolarHBondContact O-N 3.09Å; L363-L367 PolarHBondContact O-N 3.46Å
364	L	95.6	Very high	91.9	Very high	55 Å²	55	63.9 Å²	63.9	29%	0.288	33%	0.329	S	S	.	.	H	α-helix	trans	-62.7	-37.3	177.7	-69.8	173.9	0	0	0	111.6	P354 L360 L361 L367 R368 L410	P354-L364 HydrophobicContact CG-CD1 4.49Å; L360-L364 HydrophobicContact CD1-CD2 4.49Å; L360-L364 HydrophobicContact CD1-CG 4.14Å; L360-L364 HydrophobicContact CG-CD1 4.04Å; L360-L364 HydrophobicContact CG-CG 4.16Å; L360-L364 WeakPolarHBondContact O-CG 3.27Å; L360-L364 PolarHBondContact O-N 3.16Å; L361-L364 PolarHBondContact O-N 2.71Å; L364-L367 PolarHBondContact O-N 2.92Å; L364-R368 PolarHBondContact O-N 2.89Å; L364-L410 HydrophobicContact CB-CD1 4.49Å; L364-L410 HydrophobicContact CB-CD2 4.25Å; L364-L410 HydrophobicContact CD1-CD2 4.47Å
365	V	96.3	Very high	92.1	Very high	1 Å²	1	63.9 Å²	63.9	1%	0.006	33%	0.329	C	S	.	.	H	α-helix	trans	-66.4	-45.3	174.9	173.6	0	0	0	0	111.3	C296 L299 V300 L361 P362 L363 L367 R368 L410	C296-V365 HydrophobicContact CB-CG2 4.03Å; L299-V365 HydrophobicContact CB-CG1 3.56Å; L299-V365 HydrophobicContact CD1-CG1 4.19Å; V300-V365 HydrophobicContact CG2-CB 4.33Å; V300-V365 HydrophobicContact CG2-CG1 3.9Å; V300-V365 HydrophobicContact CG2-CG2 3.66Å; L361-V365 HydrophobicContact CD1-CG2 4.27Å; L361-V365 WeakPolarHBondContact O-CG2 3.43Å; L361-V365 PolarHBondContact O-N 3.14Å; L361-V365 VanDerWaalsContact O-N 3.09Å; P362-V365 PolarHBondContact O-N 3.26Å; L363-V365 VanDerWaalsContact C-N 3.29Å; L363-V365 PolarHBondContact O-N 2.94Å; V365-L367 VanDerWaalsContact C-N 3.29Å; V365-L367 PolarHBondContact O-N 3.44Å; V365-R368 VanDerWaalsContact O-CB 3.29Å; V365-R368 WeakPolarHBondContact O-CB 3.2Å; V365-R368 PolarHBondContact O-N 3.5Å; V365-R368 VanDerWaalsContact O-N 3.12Å; V365-L410 HydrophobicContact CG2-CD1 4.2Å
366	C	96	Very high	92.4	Very high	72 Å²	72	59.9 Å²	59.9	49%	0.486	31%	0.307	S	S	.	.	H	α-helix	trans	-61.1	-38.1	175.6	-72.2	0	0	0	0	112.1	P362 L363 R368 F369	P362-C366 WeakPolarHBondContact O-CB 3.32Å; P362-C366 PolarHBondContact O-N 3.18Å; P362-C366 PolarHBondContact O-SG 3.43Å; L363-C366 PolarHBondContact O-N 3.09Å; C366-R368 PolarHBondContact O-N 3.31Å; C366-F369 WeakPolarHBondContact O-CB 3.42Å; C366-F369 WeakPolarHBondContact O-CD2 3.37Å; C366-F369 PolarHBondContact O-N 3.41Å; C366-F369 VanDerWaalsContact O-N 3.11Å
367	L	96.8	Very high	93	Very high	112 Å²	112	59.4 Å²	59.4	59%	0.586	31%	0.306	S	S	*	.	H	α-helix	trans	-61	-27.5	177.1	-172.3	63.6	0	0	0	112.4	L363 L364 V365 F369 L370	L363-L367 PolarHBondContact O-N 3.46Å; L364-L367 PolarHBondContact O-N 2.92Å; V365-L367 VanDerWaalsContact C-N 3.29Å; V365-L367 PolarHBondContact O-N 3.44Å; L367-F369 PolarHBondContact O-N 3.12Å; L367-L370 VanDerWaalsContact O-CB 3.25Å; L367-L370 WeakPolarHBondContact O-CB 2.9Å; L367-L370 PolarHBondContact O-N 3.07Å; L367-L370 VanDerWaalsContact O-N 3.1Å
368	R	97.8	Very high	93.6	Very high	3 Å²	3	51.8 Å²	51.8	1%	0.011	27%	0.266	C	S	.	.	G	3₁₀ helix	trans	-60.5	-26.9	176.6	-65	-178.4	63.4	75.8	1.2	113.1	V303 T304 L364 V365 C366 L370 F371 F403 S406 L410	V303-R368 HydrophobicContact CG1-CB 4.09Å; V303-R368 WeakPolarHBondContact CG1-O 3.23Å; T304-R368 PolarHBondContact OG1-NH2 3.36Å; L364-R368 PolarHBondContact O-N 2.89Å; V365-R368 VanDerWaalsContact O-CB 3.29Å; V365-R368 WeakPolarHBondContact O-CB 3.2Å; V365-R368 PolarHBondContact O-N 3.5Å; V365-R368 VanDerWaalsContact O-N 3.12Å; C366-R368 PolarHBondContact O-N 3.31Å; R368-L370 PolarHBondContact O-N 2.96Å; R368-L370 VanDerWaalsContact O-N 3.1Å; R368-F371 HydrophobicContact CB-CD2 4.18Å; R368-F371 WeakPolarHBondContact O-CB 3.25Å; R368-F371 VanDerWaalsContact O-CD2 3.29Å; R368-F371 WeakPolarHBondContact O-CD2 3.32Å; R368-F371 PolarHBondContact O-N 3.31Å; R368-F403 PolarHBondContact NH1-O 3.35Å; R368-F403 PolarHBondContact NH2-O 3.3Å; R368-S406 PolarHBondContact NH1-OG 3.06Å; R368-L410 HydrophobicContact CG-CD1 4.29Å
369	F	96.5	Very high	93.6	Very high	88 Å²	88	52.4 Å²	52.4	39%	0.386	26%	0.263	S	S	.	.	G	3₁₀ helix	trans	-60.4	-22.4	178	-78.6	-95	0	0	0	112.5	L299 V303 C366 L367 F371 V372 P373	L299-F369 HydrophobicContact CB-CE2 4.31Å; L299-F369 HydrophobicContact CD2-CE2 4.24Å; L299-F369 HydrophobicContact CD2-CZ 3.87Å; V303-F369 HydrophobicContact CG2-CD1 3.75Å; V303-F369 HydrophobicContact CG2-CD2 3.7Å; V303-F369 HydrophobicContact CG2-CE1 3.64Å; V303-F369 HydrophobicContact CG2-CE2 3.59Å; V303-F369 HydrophobicContact CG2-CG 3.78Å; V303-F369 HydrophobicContact CG2-CZ 3.55Å; C366-F369 WeakPolarHBondContact O-CB 3.42Å; C366-F369 WeakPolarHBondContact O-CD2 3.37Å; C366-F369 PolarHBondContact O-N 3.41Å; C366-F369 VanDerWaalsContact O-N 3.11Å; L367-F369 PolarHBondContact O-N 3.12Å; F369-F371 PolarHBondContact O-N 2.96Å; F369-V372 PolarHBondContact O-N 3.26Å; F369-P373 VanDerWaalsContact O-CD 3.26Å; F369-P373 WeakPolarHBondContact O-CD 3.26Å
370	L	96.7	Very high	93.3	Very high	100 Å²	100	41.7 Å²	41.7	52%	0.524	22%	0.223	S	C	.	.	G	3₁₀ helix	trans	-62	-28	172.7	-172.3	64.1	0	0	0	112.6	L367 R368 V372 P373 L374	L367-L370 VanDerWaalsContact O-CB 3.25Å; L367-L370 WeakPolarHBondContact O-CB 2.9Å; L367-L370 PolarHBondContact O-N 3.07Å; L367-L370 VanDerWaalsContact O-N 3.1Å; R368-L370 PolarHBondContact O-N 2.96Å; R368-L370 VanDerWaalsContact O-N 3.1Å; L370-V372 PolarHBondContact O-N 2.65Å; L370-P373 VanDerWaalsContact O-CD 3.23Å; L370-P373 WeakPolarHBondContact O-CD 3.34Å; L370-P373 VanDerWaalsContact O-CG 3.3Å; L370-P373 WeakPolarHBondContact O-CG 3.43Å; L370-L374 HydrophobicContact CG-CD1 4.07Å; L370-L374 HydrophobicContact CG-CG 4.39Å; L370-L374 VanDerWaalsContact O-CG 3.22Å; L370-L374 WeakPolarHBondContact O-CG 3.37Å; L370-L374 PolarHBondContact O-N 3.16Å
371	F	96.8	Very high	92.2	Very high	27 Å²	27	43.3 Å²	43.3	12%	0.118	24%	0.236	C	C	.	.	H	α-helix	trans	-65.8	-26.8	178.2	-68.4	-64.7	0	0	0	113	R368 F369 L374 F375 L402 F403	R368-F371 HydrophobicContact CB-CD2 4.18Å; R368-F371 WeakPolarHBondContact O-CB 3.25Å; R368-F371 VanDerWaalsContact O-CD2 3.29Å; R368-F371 WeakPolarHBondContact O-CD2 3.32Å; R368-F371 PolarHBondContact O-N 3.31Å; F369-F371 PolarHBondContact O-N 2.96Å; F371-L374 HydrophobicContact CD1-CD1 4.21Å; F371-L374 PolarHBondContact O-N 3.42Å; F371-F375 HydrophobicContact CB-CD2 4.17Å; F371-F375 HydrophobicContact CB-CE2 4.01Å; F371-F375 HydrophobicContact CD1-CE2 4.4Å; F371-F375 WeakPolarHBondContact O-CD2 3.4Å; F371-F375 PolarHBondContact O-N 3.46Å; F371-L402 HydrophobicContact CE1-CB 4.03Å; F371-L402 HydrophobicContact CZ-CB 3.9Å; F371-F403 HydrophobicContact CB-CD2 3.73Å; F371-F403 HydrophobicContact CB-CE2 4.23Å; F371-F403 HydrophobicContact CD1-CB 3.97Å; F371-F403 HydrophobicContact CD1-CD2 4.38Å; F371-F403 HydrophobicContact CD2-CB 4.27Å; F371-F403 AromaticContact CD2-CD2 3.69Å; F371-F403 HydrophobicContact CD2-CD2 3.69Å; F371-F403 HydrophobicContact CD2-CG 4.48Å; F371-F403 HydrophobicContact CE1-CB 4.03Å; F371-F403 HydrophobicContact CE2-CB 4.33Å; F371-F403 HydrophobicContact CE2-CD2 4.4Å; F371-F403 HydrophobicContact CG-CB 4.11Å; F371-F403 AromaticContact CG-CD2 3.69Å; F371-F403 HydrophobicContact CG-CD2 3.69Å; F371-F403 HydrophobicContact CG-CG 4.36Å; F371-F403 HydrophobicContact CZ-CB 4.22Å
372	V	95.3	Very high	90.9	Very high	16 Å²	16	51.5 Å²	51.5	10%	0.097	27%	0.274	C	S	.	.	H	α-helix	trans	-59.7	-60.4	179.8	-179.6	0	0	0	0	111.7	V303 V307 F369 L370 L374 F375 M376 F452	V303-V372 HydrophobicContact CG1-CG2 4.07Å; V307-V372 HydrophobicContact CG1-CB 4.32Å; V307-V372 HydrophobicContact CG1-CG1 4.18Å; V307-V372 HydrophobicContact CG1-CG2 4.16Å; F369-V372 PolarHBondContact O-N 3.26Å; L370-V372 PolarHBondContact O-N 2.65Å; V372-L374 VanDerWaalsContact C-N 3.3Å; V372-L374 PolarHBondContact O-N 3.42Å; V372-F375 PolarHBondContact O-N 3.07Å; V372-M376 HydrophobicContact CG1-SD 4.1Å; V372-M376 WeakPolarHBondContact O-CG 3.45Å; V372-M376 PolarHBondContact O-N 3.42Å; V372-F452 HydrophobicContact CG1-CD2 4.02Å; V372-F452 HydrophobicContact CG1-CE1 4.33Å; V372-F452 HydrophobicContact CG1-CE2 3.48Å; V372-F452 VanDerWaalsContact CG1-CE2 3.48Å; V372-F452 HydrophobicContact CG1-CZ 3.68Å; V372-F452 HydrophobicContact CG2-CE2 4.46Å
373	P	93.6	Very high	89.6	Confident	58 Å²	58	52.2 Å²	52.2	38%	0.377	27%	0.273	S	S	.	.	H	α-helix	trans	-63.1	-36.1	176.5	25.4	-34.4	0	0	0	112	F369 L370 F375 M376 L377	F369-P373 VanDerWaalsContact O-CD 3.26Å; F369-P373 WeakPolarHBondContact O-CD 3.26Å; L370-P373 VanDerWaalsContact O-CD 3.23Å; L370-P373 WeakPolarHBondContact O-CD 3.34Å; L370-P373 VanDerWaalsContact O-CG 3.3Å; L370-P373 WeakPolarHBondContact O-CG 3.43Å; P373-F375 VanDerWaalsContact C-N 3.34Å; P373-F375 PolarHBondContact O-N 3.03Å; P373-M376 PolarHBondContact O-N 3.13Å; P373-L377 HydrophobicContact CB-CD1 4.39Å; P373-L377 VanDerWaalsContact O-CB 3.31Å; P373-L377 WeakPolarHBondContact O-CB 3.31Å; P373-L377 VanDerWaalsContact O-CD1 3.32Å; P373-L377 WeakPolarHBondContact O-CD1 2.86Å; P373-L377 WeakPolarHBondContact O-CG 3.41Å; P373-L377 PolarHBondContact O-N 2.91Å
374	L	94.2	Very high	88.1	Confident	30 Å²	30	51.2 Å²	51.2	16%	0.157	28%	0.275	C	S	.	.	H	α-helix	trans	-56.8	-45.7	178.4	-71.4	176.7	0	0	0	112.1	L370 F371 V372 C378 F390 F399	L370-L374 HydrophobicContact CG-CD1 4.07Å; L370-L374 HydrophobicContact CG-CG 4.39Å; L370-L374 VanDerWaalsContact O-CG 3.22Å; L370-L374 WeakPolarHBondContact O-CG 3.37Å; L370-L374 PolarHBondContact O-N 3.16Å; F371-L374 HydrophobicContact CD1-CD1 4.21Å; F371-L374 PolarHBondContact O-N 3.42Å; V372-L374 VanDerWaalsContact C-N 3.3Å; V372-L374 PolarHBondContact O-N 3.42Å; L374-C378 PolarHBondContact O-SG 3.02Å; L374-F390 HydrophobicContact CD2-CE2 3.73Å; L374-F390 HydrophobicContact CD2-CZ 3.8Å; L374-F399 HydrophobicContact CB-CD2 3.92Å; L374-F399 HydrophobicContact CB-CE2 3.94Å; L374-F399 HydrophobicContact CB-CG 4.39Å; L374-F399 HydrophobicContact CB-CZ 4.42Å; L374-F399 HydrophobicContact CD1-CD1 4.19Å; L374-F399 HydrophobicContact CD1-CE1 4.16Å; L374-F399 HydrophobicContact CD1-CG 4.48Å; L374-F399 HydrophobicContact CD1-CZ 4.41Å; L374-F399 HydrophobicContact CD2-CE1 4.28Å; L374-F399 HydrophobicContact CD2-CE2 4.08Å; L374-F399 HydrophobicContact CD2-CZ 3.81Å; L374-F399 HydrophobicContact CG-CE2 4.44Å; L374-F399 HydrophobicContact CG-CZ 4.43Å
375	F	93.3	Very high	86.9	Confident	0 Å²	0	57.4 Å²	57.4	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-73.5	-37.9	176.8	-73.2	-58.5	0	0	0	113.4	V307 T312 F371 V372 P373 L377 C378 F396 F399 M400 F403	V307-F375 HydrophobicContact CB-CD2 4.35Å; V307-F375 HydrophobicContact CG2-CD2 3.96Å; V307-F375 HydrophobicContact CG2-CE2 4.42Å; T312-F375 HydrophobicContact CG2-CB 4.39Å; T312-F375 HydrophobicContact CG2-CD1 3.87Å; T312-F375 HydrophobicContact CG2-CD2 4.2Å; T312-F375 HydrophobicContact CG2-CE1 4.18Å; T312-F375 HydrophobicContact CG2-CE2 4.47Å; T312-F375 HydrophobicContact CG2-CG 3.9Å; T312-F375 HydrophobicContact CG2-CZ 4.48Å; F371-F375 HydrophobicContact CB-CD2 4.17Å; F371-F375 HydrophobicContact CB-CE2 4.01Å; F371-F375 HydrophobicContact CD1-CE2 4.4Å; F371-F375 WeakPolarHBondContact O-CD2 3.4Å; F371-F375 PolarHBondContact O-N 3.46Å; V372-F375 PolarHBondContact O-N 3.07Å; P373-F375 VanDerWaalsContact C-N 3.34Å; P373-F375 PolarHBondContact O-N 3.03Å; F375-L377 PolarHBondContact O-N 3.48Å; F375-C378 WeakPolarHBondContact O-CB 3.49Å; F375-C378 PolarHBondContact O-N 3.33Å; F375-F396 AromaticContact CD1-CD2 3.93Å; F375-F396 HydrophobicContact CD1-CD2 3.93Å; F375-F396 AromaticContact CD1-CE2 3.93Å; F375-F396 HydrophobicContact CD1-CE2 3.93Å; F375-F396 AromaticContact CE1-CD2 3.96Å; F375-F396 HydrophobicContact CE1-CD2 3.96Å; F375-F396 AromaticContact CE1-CE2 3.94Å; F375-F396 HydrophobicContact CE1-CE2 3.94Å; F375-F399 HydrophobicContact CD1-CB 4.42Å; F375-F399 HydrophobicContact CE1-CB 3.65Å; F375-F399 HydrophobicContact CZ-CB 3.73Å; F375-M400 HydrophobicContact CD1-SD 4.46Å; F375-M400 HydrophobicContact CE1-CG 3.82Å; F375-M400 HydrophobicContact CE1-SD 3.44Å; F375-M400 WeakPolarHBondContact CE1-SD 3.39Å; F375-M400 HydrophobicContact CE2-SD 4.22Å; F375-M400 HydrophobicContact CZ-CG 4.04Å; F375-M400 HydrophobicContact CZ-SD 3.3Å; F375-M400 WeakPolarHBondContact CZ-SD 3.32Å; F375-F403 HydrophobicContact CE2-CB 3.98Å; F375-F403 HydrophobicContact CE2-CD1 4.02Å; F375-F403 AromaticContact CE2-CD2 3.93Å; F375-F403 HydrophobicContact CE2-CD2 3.93Å; F375-F403 HydrophobicContact CE2-CE1 4.39Å; F375-F403 HydrophobicContact CE2-CE2 4.29Å; F375-F403 AromaticContact CE2-CG 3.73Å; F375-F403 HydrophobicContact CE2-CG 3.73Å; F375-F403 HydrophobicContact CE2-CZ 4.48Å; F375-F403 HydrophobicContact CZ-CB 4.03Å; F375-F403 HydrophobicContact CZ-CD1 4.26Å; F375-F403 HydrophobicContact CZ-CG 4.14Å
376	M	90	Very high	86	Confident	17 Å²	17	60.1 Å²	60.1	8%	0.084	31%	0.309	C	S	.	.	H	α-helix	trans	-63.7	-25.2	176.9	-69.7	-174.8	79.8	0	0	112.7	I311 V372 P373 L386 F452 L455 L456	I311-M376 HydrophobicContact CG2-CG 4.37Å; V372-M376 HydrophobicContact CG1-SD 4.1Å; V372-M376 WeakPolarHBondContact O-CG 3.45Å; V372-M376 PolarHBondContact O-N 3.42Å; P373-M376 PolarHBondContact O-N 3.13Å; M376-L386 HydrophobicContact CB-CD1 4.47Å; M376-L386 HydrophobicContact CE-CD1 3.67Å; M376-F452 HydrophobicContact CE-CB 4.12Å; M376-F452 HydrophobicContact CE-CD1 4.4Å; M376-F452 HydrophobicContact CE-CG 4.49Å; M376-F452 HydrophobicContact SD-CB 4.26Å; M376-F452 HydrophobicContact SD-CD1 4.13Å; M376-F452 HydrophobicContact SD-CG 4.15Å; M376-L455 HydrophobicContact CE-CB 4.11Å; M376-L456 HydrophobicContact CE-CG 4.37Å
377	L	90.2	Very high	85.4	Confident	31 Å²	31	60.4 Å²	60.4	16%	0.162	31%	0.31	C	S	.	.	T	Hydrogen-bonded Turn	trans	-92.7	-0.3	-179.9	-66.1	166.2	0	0	0	114	P373 F375 P387 L389 F390	P373-L377 HydrophobicContact CB-CD1 4.39Å; P373-L377 VanDerWaalsContact O-CB 3.31Å; P373-L377 WeakPolarHBondContact O-CB 3.31Å; P373-L377 VanDerWaalsContact O-CD1 3.32Å; P373-L377 WeakPolarHBondContact O-CD1 2.86Å; P373-L377 WeakPolarHBondContact O-CG 3.41Å; P373-L377 PolarHBondContact O-N 2.91Å; F375-L377 PolarHBondContact O-N 3.48Å; L377-P387 HydrophobicContact CD2-CG 4.31Å; L377-P387 WeakPolarHBondContact CD2-O 3.33Å; L377-L389 HydrophobicContact CB-CB 4.32Å; L377-L389 HydrophobicContact CD1-CD1 3.89Å; L377-L389 HydrophobicContact CD2-CD1 4.13Å; L377-L389 HydrophobicContact CD2-CG 4.38Å; L377-L389 HydrophobicContact CG-CD1 4.46Å; L377-L389 PolarHBondContact O-N 3.46Å; L377-F390 HydrophobicContact CB-CD2 3.93Å; L377-F390 HydrophobicContact CB-CE2 4.07Å; L377-F390 HydrophobicContact CD1-CE2 4.47Å; L377-F390 PolarHBondContact O-N 3.37Å
378	C	88.8	Confident	84.8	Confident	1 Å²	1	57.9 Å²	57.9	1%	0.007	30%	0.299	C	S	.	.	B	Isolated β-bridge	trans	-69.9	176.9	172.3	-74.4	0	0	0	0	112.4	V315 L374 F375 V380 R383	V315-C378 HydrophobicContact CG1-CB 4.19Å; V315-C378 HydrophobicContact CG2-CB 3.98Å; L374-C378 PolarHBondContact O-SG 3.02Å; F375-C378 WeakPolarHBondContact O-CB 3.49Å; F375-C378 PolarHBondContact O-N 3.33Å; C378-V380 PolarHBondContact O-N 2.88Å; C378-V380 VanDerWaalsContact O-N 3.12Å; C378-R383 VanDerWaalsContact O-CZ 3.32Å; C378-R383 PolarHBondContact O-NH1 3.04Å; C378-R383 PolarHBondContact O-NH2 3.23Å
379	H	83.9	Confident	84.3	Confident	59 Å²	59	62.9 Å²	62.9	27%	0.273	33%	0.325	S	S	.	.			trans	-77	91.9	-177.4	-168	71.1	0	0	0	114.5	V315 T316 T388 F390	V315-H379 WeakPolarHBondContact CA-O 3.5Å; T316-H379 PolarHBondContact N-O 3Å; H379-T388 HydrophobicContact CB-CG2 4.35Å; H379-F390 PolarHBondContact N-O 3.03Å
380	V	82.6	Confident	83.9	Confident	4 Å²	4	60.8 Å²	60.8	2%	0.024	32%	0.316	C	S	.	.			trans	-104.3	122.5	168.1	-176.1	0	0	0	0	110.3	M314 V315 C378 R383 L456	M314-V380 HydrophobicContact CB-CG1 4.23Å; M314-V380 HydrophobicContact CE-CG1 4.37Å; V315-V380 HydrophobicContact CG2-CG2 4.19Å; C378-V380 PolarHBondContact O-N 2.88Å; C378-V380 VanDerWaalsContact O-N 3.12Å; V380-R383 PolarHBondContact O-NE 3.36Å; V380-R383 PolarHBondContact O-NH2 2.86Å; V380-R383 VanDerWaalsContact O-NH2 3.1Å; V380-L456 HydrophobicContact CB-CD2 4.48Å; V380-L456 HydrophobicContact CG2-CD2 4.29Å
381	P	68.4	Low	83.3	Confident	82 Å²	82	59 Å²	59	53%	0.532	31%	0.311	S	S	.	.	S	Bend	trans	-72	-27.8	-173.2	-23.3	34.3	0	0	0	116.6	T316	T316-P381 HydrophobicContact CG2-CG 3.8Å; T316-P381 WeakPolarHBondContact OG1-CD 3.34Å; T316-P381 WeakPolarHBondContact OG1-CG 3.49Å
382	Q	65.8	Low	82.9	Confident	179 Å²	179	63.3 Å²	63.3	84%	0.836	33%	0.331	S	S	*	.	S	Bend	trans	-119.1	69.8	-174.9	-69	-178.3	-9.4	0	0	110.2
383	R	68.7	Low	82.7	Confident	50 Å²	50	63.5 Å²	63.5	19%	0.189	33%	0.332	C	S	.	.			trans	-111.4	149.3	177.3	73.1	-177.9	82.9	-168.1	10.6	110.9	C378 V380 L386 P387 T388 L456	C378-R383 VanDerWaalsContact O-CZ 3.32Å; C378-R383 PolarHBondContact O-NH1 3.04Å; C378-R383 PolarHBondContact O-NH2 3.23Å; V380-R383 PolarHBondContact O-NE 3.36Å; V380-R383 PolarHBondContact O-NH2 2.86Å; V380-R383 VanDerWaalsContact O-NH2 3.1Å; R383-L386 WeakPolarHBondContact CD-O 3.23Å; R383-P387 PolarHBondContact NH1-O 3Å; R383-P387 VanDerWaalsContact NH1-O 3.12Å; R383-T388 PolarHBondContact NH1-OG1 3.16Å; R383-T388 PolarHBondContact NH2-OG1 3.45Å; R383-L456 CarbonylContact C-O 3.59Å; R383-L456 WeakPolarHBondContact CA-O 3.4Å; R383-L456 WeakPolarHBondContact CB-O 3.39Å
384	S	62.1	Low	82.6	Confident	90 Å²	90	63.4 Å²	63.4	63%	0.629	34%	0.336	S	S	*	.	S	Bend	trans	-108.2	-32.3	-175.2	61.6	0	0	0	0	113.7	L456	S384-L456 PolarHBondContact N-O 3.19Å; S384-L456 PolarHBondContact OG-O 3.34Å; S384-L456 PolarHBondContact OG-OXT 3.02Å
385	R	71.3	Confident	82.6	Confident	186 Å²	186	66.8 Å²	66.8	70%	0.702	35%	0.347	S	S	*	.	S	Bend	trans	-124.1	-25.1	-168.8	-54.9	-176.9	-148.6	-129.8	5.7	117.3
386	L	77.9	Confident	82.6	Confident	57 Å²	57	67 Å²	67	30%	0.298	35%	0.348	S	S	.	.			trans	-107.6	144.2	-168.9	-75.7	161.8	0	0	0	113.3	M376 R383	M376-L386 HydrophobicContact CB-CD1 4.47Å; M376-L386 HydrophobicContact CE-CD1 3.67Å; R383-L386 WeakPolarHBondContact CD-O 3.23Å
387	P	83.7	Confident	82.9	Confident	79 Å²	79	69 Å²	69	51%	0.513	36%	0.359	S	S	.	.			trans	-74.1	159.1	174.8	30.6	-34.3	0	0	0	112.7	L377 R383	L377-P387 HydrophobicContact CD2-CG 4.31Å; L377-P387 WeakPolarHBondContact CD2-O 3.33Å; R383-P387 PolarHBondContact NH1-O 3Å; R383-P387 VanDerWaalsContact NH1-O 3.12Å
388	T	84.5	Confident	83.2	Confident	59 Å²	59	71 Å²	71	36%	0.362	37%	0.372	S	S	.	.			trans	-94.1	110	170.4	-44.5	0	0	0	0	109.3	H379 R383 P391	H379-T388 HydrophobicContact CB-CG2 4.35Å; R383-T388 PolarHBondContact NH1-OG1 3.16Å; R383-T388 PolarHBondContact NH2-OG1 3.45Å; T388-P391 HydrophobicContact CG2-CB 4.41Å
389	L	87.3	Confident	83.6	Confident	107 Å²	107	72.2 Å²	72.2	56%	0.56	38%	0.377	S	S	*	.	S	Bend	trans	-97.8	-27.5	176.4	-69.7	176.3	0	0	0	112.6	L377 P391	L377-L389 HydrophobicContact CB-CB 4.32Å; L377-L389 HydrophobicContact CD1-CD1 3.89Å; L377-L389 HydrophobicContact CD2-CD1 4.13Å; L377-L389 HydrophobicContact CD2-CG 4.38Å; L377-L389 HydrophobicContact CG-CD1 4.46Å; L377-L389 PolarHBondContact O-N 3.46Å; L389-P391 VanDerWaalsContact C-CD 3.5Å; L389-P391 WeakPolarHBondContact O-CD 3.43Å
390	F	88	Confident	84.2	Confident	45 Å²	45	69.4 Å²	69.4	20%	0.197	36%	0.364	C	S	.	.	B	Isolated β-bridge	trans	-117.6	81.3	-178.3	-53.6	-68.5	0	0	0	110.5	L374 L377 H379 Y395 F399	L374-F390 HydrophobicContact CD2-CE2 3.73Å; L374-F390 HydrophobicContact CD2-CZ 3.8Å; L377-F390 HydrophobicContact CB-CD2 3.93Å; L377-F390 HydrophobicContact CB-CE2 4.07Å; L377-F390 HydrophobicContact CD1-CE2 4.47Å; L377-F390 PolarHBondContact O-N 3.37Å; H379-F390 PolarHBondContact N-O 3.03Å; F390-Y395 HydrophobicContact CB-CD2 4.11Å; F390-Y395 HydrophobicContact CB-CG 4.05Å; F390-Y395 AromaticContact CD1-CD1 3.86Å; F390-Y395 HydrophobicContact CD1-CD1 3.86Å; F390-Y395 HydrophobicContact CD1-CD2 4.18Å; F390-Y395 HydrophobicContact CD1-CE1 4.22Å; F390-Y395 AromaticContact CD1-CG 3.84Å; F390-Y395 HydrophobicContact CD1-CG 3.84Å; F390-Y395 HydrophobicContact CE1-CD1 4.44Å; F390-Y395 HydrophobicContact CG-CG 4.31Å; F390-F399 HydrophobicContact CB-CE2 4.49Å; F390-F399 HydrophobicContact CD1-CE2 4.33Å; F390-F399 HydrophobicContact CD1-CZ 4.16Å; F390-F399 AromaticContact CD2-CE2 3.87Å; F390-F399 HydrophobicContact CD2-CE2 3.87Å; F390-F399 HydrophobicContact CD2-CZ 4.33Å; F390-F399 HydrophobicContact CE1-CZ 4.12Å; F390-F399 HydrophobicContact CE2-CE2 4.15Å; F390-F399 HydrophobicContact CE2-CZ 4.3Å; F390-F399 AromaticContact CG-CE2 3.97Å; F390-F399 HydrophobicContact CG-CE2 3.97Å; F390-F399 HydrophobicContact CG-CZ 4.27Å; F390-F399 HydrophobicContact CZ-CE2 4.5Å; F390-F399 HydrophobicContact CZ-CZ 4.19Å
391	P	82.9	Confident	84.9	Confident	63 Å²	63	72.4 Å²	72.4	41%	0.409	38%	0.38	S	S	.	.			trans	-76.9	-29.5	-177.4	29.2	-34	0	0	0	112.9	S318 T388 L389	S318-P391 WeakPolarHBondContact CB-O 3.49Å; S318-P391 PolarHBondContact OG-O 2.72Å; T388-P391 HydrophobicContact CG2-CB 4.41Å; L389-P391 VanDerWaalsContact C-CD 3.5Å; L389-P391 WeakPolarHBondContact O-CD 3.43Å
392	Q	88.7	Confident	86.3	Confident	116 Å²	116	72.6 Å²	72.6	54%	0.542	38%	0.376	S	S	.	.	S	Bend	trans	-79.4	138.7	-175.1	-61.5	174.6	-4.8	0	0	112.1	A394 Y395	Q392-A394 PolarHBondContact O-N 3.42Å; Q392-A394 VanDerWaalsContact O-N 3.13Å; Q392-Y395 HydrophobicContact CB-CD2 3.86Å; Q392-Y395 HydrophobicContact CB-CE2 4.05Å; Q392-Y395 HydrophobicContact CG-CE2 4.4Å; Q392-Y395 PolarHBondContact O-N 3.1Å; Q392-Y395 VanDerWaalsContact O-N 3.17Å
393	D	90.4	Very high	87.9	Confident	21 Å²	21	64.1 Å²	64.1	11%	0.112	34%	0.336	C	S	.	.	H	α-helix	trans	-56.6	-31.5	179.9	-62.1	13.5	0	0	0	112.9	S317 S318 F328 Y395 F396 I397	S317-D393 WeakPolarHBondContact CB-OD2 3.27Å; S317-D393 PolarHBondContact OG-OD2 2.83Å; S318-D393 WeakPolarHBondContact CB-OD1 3.46Å; S318-D393 PolarHBondContact N-OD1 3.43Å; S318-D393 PolarHBondContact OG-OD1 3.27Å; F328-D393 HydrophobicContact CE2-CB 4.04Å; D393-Y395 VanDerWaalsContact C-N 3.28Å; D393-Y395 PolarHBondContact O-N 3.38Å; D393-F396 PolarHBondContact O-N 3.02Å; D393-I397 WeakPolarHBondContact O-CG1 3.13Å; D393-I397 PolarHBondContact O-N 3.01Å
394	A	92	Very high	89.3	Confident	56 Å²	56	61.7 Å²	61.7	46%	0.463	33%	0.327	S	S	.	.	H	α-helix	trans	-59.4	-35.3	-179.4	0	0	0	0	0	113.1	Q392 T398	Q392-A394 PolarHBondContact O-N 3.42Å; Q392-A394 VanDerWaalsContact O-N 3.13Å; A394-T398 WeakPolarHBondContact O-CB 3.14Å; A394-T398 PolarHBondContact O-N 2.95Å; A394-T398 PolarHBondContact O-OG1 3.22Å
395	Y	93.6	Very high	91	Very high	101 Å²	101	59.7 Å²	59.7	40%	0.396	31%	0.309	S	S	.	.	H	α-helix	trans	-65.8	-49	176.3	-69.1	-70	0	0	0	110.9	F390 Q392 D393 I397 T398 F399	F390-Y395 HydrophobicContact CB-CD2 4.11Å; F390-Y395 HydrophobicContact CB-CG 4.05Å; F390-Y395 AromaticContact CD1-CD1 3.86Å; F390-Y395 HydrophobicContact CD1-CD1 3.86Å; F390-Y395 HydrophobicContact CD1-CD2 4.18Å; F390-Y395 HydrophobicContact CD1-CE1 4.22Å; F390-Y395 AromaticContact CD1-CG 3.84Å; F390-Y395 HydrophobicContact CD1-CG 3.84Å; F390-Y395 HydrophobicContact CE1-CD1 4.44Å; F390-Y395 HydrophobicContact CG-CG 4.31Å; Q392-Y395 HydrophobicContact CB-CD2 3.86Å; Q392-Y395 HydrophobicContact CB-CE2 4.05Å; Q392-Y395 HydrophobicContact CG-CE2 4.4Å; Q392-Y395 PolarHBondContact O-N 3.1Å; Q392-Y395 VanDerWaalsContact O-N 3.17Å; D393-Y395 VanDerWaalsContact C-N 3.28Å; D393-Y395 PolarHBondContact O-N 3.38Å; Y395-I397 VanDerWaalsContact C-N 3.33Å; Y395-I397 PolarHBondContact O-N 3.2Å; Y395-T398 PolarHBondContact O-N 2.82Å; Y395-F399 HydrophobicContact CD1-CZ 4.19Å; Y395-F399 WeakPolarHBondContact O-CB 3.47Å; Y395-F399 WeakPolarHBondContact O-CD1 3.4Å; Y395-F399 WeakPolarHBondContact O-CD2 3.26Å; Y395-F399 WeakPolarHBondContact O-CG 3.32Å; Y395-F399 PolarHBondContact O-N 3Å
396	F	94.3	Very high	92.2	Very high	4 Å²	4	52.2 Å²	52.2	2%	0.018	29%	0.285	C	S	.	.	H	α-helix	trans	-58.2	-45.5	178.2	176.8	-100.3	0	0	0	111.7	T312 V315 F328 C332 C333 F375 D393 T398 F399 M400	T312-F396 HydrophobicContact CG2-CE2 4.3Å; V315-F396 HydrophobicContact CB-CD2 4.12Å; V315-F396 HydrophobicContact CB-CE2 3.96Å; V315-F396 HydrophobicContact CB-CZ 4.42Å; V315-F396 HydrophobicContact CG1-CD2 3.83Å; V315-F396 HydrophobicContact CG1-CE2 4.17Å; V315-F396 HydrophobicContact CG1-CG 4.07Å; V315-F396 HydrophobicContact CG2-CD2 4Å; V315-F396 HydrophobicContact CG2-CE2 3.83Å; F328-F396 HydrophobicContact CE1-CD1 4.08Å; F328-F396 HydrophobicContact CE1-CE1 4.13Å; F328-F396 AromaticContact CZ-CD1 3.65Å; F328-F396 HydrophobicContact CZ-CD1 3.65Å; F328-F396 HydrophobicContact CZ-CE1 4.1Å; F328-F396 HydrophobicContact CZ-CG 4.4Å; C332-F396 HydrophobicContact CB-CD1 4.37Å; C332-F396 HydrophobicContact CB-CE1 4.12Å; C333-F396 HydrophobicContact CB-CE1 4.29Å; C333-F396 HydrophobicContact CB-CZ 4.02Å; F375-F396 AromaticContact CD1-CD2 3.93Å; F375-F396 HydrophobicContact CD1-CD2 3.93Å; F375-F396 AromaticContact CD1-CE2 3.93Å; F375-F396 HydrophobicContact CD1-CE2 3.93Å; F375-F396 AromaticContact CE1-CD2 3.96Å; F375-F396 HydrophobicContact CE1-CD2 3.96Å; F375-F396 AromaticContact CE1-CE2 3.94Å; F375-F396 HydrophobicContact CE1-CE2 3.94Å; D393-F396 PolarHBondContact O-N 3.02Å; F396-T398 PolarHBondContact O-N 3.2Å; F396-F399 PolarHBondContact O-N 3.35Å; F396-M400 HydrophobicContact CD1-CG 4.27Å; F396-M400 HydrophobicContact CD2-CG 4.42Å; F396-M400 HydrophobicContact CE1-CG 3.8Å; F396-M400 HydrophobicContact CE2-CG 3.96Å; F396-M400 HydrophobicContact CE2-SD 4.34Å; F396-M400 HydrophobicContact CZ-CG 3.63Å; F396-M400 HydrophobicContact CZ-SD 4.22Å; F396-M400 WeakPolarHBondContact O-CB 3.42Å; F396-M400 WeakPolarHBondContact O-CG 3.45Å; F396-M400 PolarHBondContact O-N 3.25Å
397	I	95.4	Very high	93.2	Very high	59 Å²	59	49.7 Å²	49.7	30%	0.303	27%	0.272	S	S	.	.	H	α-helix	trans	-62	-44.6	178.3	-66.8	167	0	0	0	111.1	C332 L336 D393 Y395 M400 L401	C332-I397 HydrophobicContact CB-CG1 4.16Å; L336-I397 HydrophobicContact CD2-CG2 3.88Å; D393-I397 WeakPolarHBondContact O-CG1 3.13Å; D393-I397 PolarHBondContact O-N 3.01Å; Y395-I397 VanDerWaalsContact C-N 3.33Å; Y395-I397 PolarHBondContact O-N 3.2Å; I397-M400 PolarHBondContact O-N 3.26Å; I397-L401 WeakPolarHBondContact O-CB 3.43Å; I397-L401 PolarHBondContact O-N 3.44Å
398	T	96.6	Very high	93.8	Very high	74 Å²	74	45.9 Å²	45.9	45%	0.454	25%	0.247	S	C	.	.	H	α-helix	trans	-64.4	-45	179.1	-57.2	0	0	0	0	111.3	A394 Y395 F396 L401 L402	A394-T398 WeakPolarHBondContact O-CB 3.14Å; A394-T398 PolarHBondContact O-N 2.95Å; A394-T398 PolarHBondContact O-OG1 3.22Å; Y395-T398 PolarHBondContact O-N 2.82Å; F396-T398 PolarHBondContact O-N 3.2Å; T398-L401 PolarHBondContact O-N 2.98Å; T398-L402 HydrophobicContact CG2-CD1 4.35Å; T398-L402 WeakPolarHBondContact O-CG 3.23Å; T398-L402 PolarHBondContact O-N 3.03Å; T398-L402 VanDerWaalsContact O-N 3.15Å
399	F	97	Very high	94.4	Very high	25 Å²	25	44.7 Å²	44.7	11%	0.11	24%	0.236	C	C	.	.	H	α-helix	trans	-62.5	-44.1	176.2	-59.3	-21.1	0	0	0	110.9	L374 F375 F390 Y395 F396 L401 L402 F403	L374-F399 HydrophobicContact CB-CD2 3.92Å; L374-F399 HydrophobicContact CB-CE2 3.94Å; L374-F399 HydrophobicContact CB-CG 4.39Å; L374-F399 HydrophobicContact CB-CZ 4.42Å; L374-F399 HydrophobicContact CD1-CD1 4.19Å; L374-F399 HydrophobicContact CD1-CE1 4.16Å; L374-F399 HydrophobicContact CD1-CG 4.48Å; L374-F399 HydrophobicContact CD1-CZ 4.41Å; L374-F399 HydrophobicContact CD2-CE1 4.28Å; L374-F399 HydrophobicContact CD2-CE2 4.08Å; L374-F399 HydrophobicContact CD2-CZ 3.81Å; L374-F399 HydrophobicContact CG-CE2 4.44Å; L374-F399 HydrophobicContact CG-CZ 4.43Å; F375-F399 HydrophobicContact CD1-CB 4.42Å; F375-F399 HydrophobicContact CE1-CB 3.65Å; F375-F399 HydrophobicContact CZ-CB 3.73Å; F390-F399 HydrophobicContact CB-CE2 4.49Å; F390-F399 HydrophobicContact CD1-CE2 4.33Å; F390-F399 HydrophobicContact CD1-CZ 4.16Å; F390-F399 AromaticContact CD2-CE2 3.87Å; F390-F399 HydrophobicContact CD2-CE2 3.87Å; F390-F399 HydrophobicContact CD2-CZ 4.33Å; F390-F399 HydrophobicContact CE1-CZ 4.12Å; F390-F399 HydrophobicContact CE2-CE2 4.15Å; F390-F399 HydrophobicContact CE2-CZ 4.3Å; F390-F399 AromaticContact CG-CE2 3.97Å; F390-F399 HydrophobicContact CG-CE2 3.97Å; F390-F399 HydrophobicContact CG-CZ 4.27Å; F390-F399 HydrophobicContact CZ-CE2 4.5Å; F390-F399 HydrophobicContact CZ-CZ 4.19Å; Y395-F399 HydrophobicContact CD1-CZ 4.19Å; Y395-F399 WeakPolarHBondContact O-CB 3.47Å; Y395-F399 WeakPolarHBondContact O-CD1 3.4Å; Y395-F399 WeakPolarHBondContact O-CD2 3.26Å; Y395-F399 WeakPolarHBondContact O-CG 3.32Å; Y395-F399 PolarHBondContact O-N 3Å; F396-F399 PolarHBondContact O-N 3.35Å; F399-L401 PolarHBondContact O-N 3.34Å; F399-L402 PolarHBondContact O-N 2.93Å; F399-F403 WeakPolarHBondContact O-CB 3.16Å; F399-F403 PolarHBondContact O-N 3.48Å
400	M	97.4	Very high	94.8	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-61.3	-42.1	177.3	-82.4	-47.3	-47.2	0	0	112.9	F308 T312 L336 F337 F375 F396 I397 F403 A404	F308-M400 HydrophobicContact CD2-CE 4.35Å; T312-M400 HydrophobicContact CG2-SD 3.98Å; L336-M400 HydrophobicContact CD2-CB 3.95Å; F337-M400 HydrophobicContact CB-CE 3.7Å; F337-M400 HydrophobicContact CD2-CE 3.54Å; F337-M400 HydrophobicContact CG-CE 4.07Å; F375-M400 HydrophobicContact CD1-SD 4.46Å; F375-M400 HydrophobicContact CE1-CG 3.82Å; F375-M400 HydrophobicContact CE1-SD 3.44Å; F375-M400 WeakPolarHBondContact CE1-SD 3.39Å; F375-M400 HydrophobicContact CE2-SD 4.22Å; F375-M400 HydrophobicContact CZ-CG 4.04Å; F375-M400 HydrophobicContact CZ-SD 3.3Å; F375-M400 WeakPolarHBondContact CZ-SD 3.32Å; F396-M400 HydrophobicContact CD1-CG 4.27Å; F396-M400 HydrophobicContact CD2-CG 4.42Å; F396-M400 HydrophobicContact CE1-CG 3.8Å; F396-M400 HydrophobicContact CE2-CG 3.96Å; F396-M400 HydrophobicContact CE2-SD 4.34Å; F396-M400 HydrophobicContact CZ-CG 3.63Å; F396-M400 HydrophobicContact CZ-SD 4.22Å; F396-M400 WeakPolarHBondContact O-CB 3.42Å; F396-M400 WeakPolarHBondContact O-CG 3.45Å; F396-M400 PolarHBondContact O-N 3.25Å; I397-M400 PolarHBondContact O-N 3.26Å; M400-F403 HydrophobicContact CE-CD1 3.82Å; M400-F403 HydrophobicContact CE-CE1 4.32Å; M400-F403 HydrophobicContact SD-CD1 4.26Å; M400-A404 WeakPolarHBondContact O-CB 3.37Å; M400-A404 PolarHBondContact O-N 3.12Å
401	L	97.7	Very high	95.2	Very high	67 Å²	67	37.7 Å²	37.7	35%	0.351	20%	0.202	S	C	.	.	H	α-helix	trans	-59.7	-53.3	178	-173.5	156.6	0	0	0	110.9	M340 I397 T398 F399 I405	M340-L401 HydrophobicContact CG-CG 4.13Å; M340-L401 HydrophobicContact SD-CD1 4.45Å; M340-L401 HydrophobicContact SD-CG 3.94Å; I397-L401 WeakPolarHBondContact O-CB 3.43Å; I397-L401 PolarHBondContact O-N 3.44Å; T398-L401 PolarHBondContact O-N 2.98Å; F399-L401 PolarHBondContact O-N 3.34Å; L401-I405 VanDerWaalsContact O-CG2 3.31Å; L401-I405 WeakPolarHBondContact O-CG2 3.4Å; L401-I405 PolarHBondContact O-N 3.39Å; L401-I405 VanDerWaalsContact O-N 3.07Å
402	L	97.9	Very high	95.8	Very high	87 Å²	87	34.7 Å²	34.7	46%	0.455	18%	0.182	S	C	.	.	H	α-helix	trans	-66.2	-41.1	-178.6	-65.4	177.1	0	0	0	112.1	F371 T398 F399 I405 S406	F371-L402 HydrophobicContact CE1-CB 4.03Å; F371-L402 HydrophobicContact CZ-CB 3.9Å; T398-L402 HydrophobicContact CG2-CD1 4.35Å; T398-L402 WeakPolarHBondContact O-CG 3.23Å; T398-L402 PolarHBondContact O-N 3.03Å; T398-L402 VanDerWaalsContact O-N 3.15Å; F399-L402 PolarHBondContact O-N 2.93Å; L402-I405 WeakPolarHBondContact O-CG2 3.46Å; L402-S406 WeakPolarHBondContact O-CB 3.44Å; L402-S406 PolarHBondContact O-N 3.17Å; L402-S406 VanDerWaalsContact O-N 3.17Å; L402-S406 PolarHBondContact O-OG 3.33Å
403	F	98.3	Very high	96.1	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-63.9	-43.4	179.8	171	-105.3	0	0	0	112.5	V303 T304 V307 F308 F337 R368 F371 F375 F399 M400 S406 N407	V303-F403 HydrophobicContact CG1-CE2 4.25Å; T304-F403 HydrophobicContact CG2-CE1 4.2Å; T304-F403 HydrophobicContact CG2-CZ 3.93Å; V307-F403 HydrophobicContact CG2-CE1 4.25Å; V307-F403 HydrophobicContact CG2-CE2 3.79Å; V307-F403 HydrophobicContact CG2-CZ 3.4Å; F308-F403 HydrophobicContact CB-CE1 3.92Å; F308-F403 HydrophobicContact CB-CZ 4.26Å; F337-F403 HydrophobicContact CD2-CD1 4.03Å; F337-F403 HydrophobicContact CD2-CE1 4.01Å; F337-F403 AromaticContact CE2-CD1 3.92Å; F337-F403 HydrophobicContact CE2-CD1 3.92Å; F337-F403 AromaticContact CE2-CE1 3.63Å; F337-F403 HydrophobicContact CE2-CE1 3.63Å; R368-F403 PolarHBondContact NH1-O 3.35Å; R368-F403 PolarHBondContact NH2-O 3.3Å; F371-F403 HydrophobicContact CB-CD2 3.73Å; F371-F403 HydrophobicContact CB-CE2 4.23Å; F371-F403 HydrophobicContact CD1-CB 3.97Å; F371-F403 HydrophobicContact CD1-CD2 4.38Å; F371-F403 HydrophobicContact CD2-CB 4.27Å; F371-F403 AromaticContact CD2-CD2 3.69Å; F371-F403 HydrophobicContact CD2-CD2 3.69Å; F371-F403 HydrophobicContact CD2-CG 4.48Å; F371-F403 HydrophobicContact CE1-CB 4.03Å; F371-F403 HydrophobicContact CE2-CB 4.33Å; F371-F403 HydrophobicContact CE2-CD2 4.4Å; F371-F403 HydrophobicContact CG-CB 4.11Å; F371-F403 AromaticContact CG-CD2 3.69Å; F371-F403 HydrophobicContact CG-CD2 3.69Å; F371-F403 HydrophobicContact CG-CG 4.36Å; F371-F403 HydrophobicContact CZ-CB 4.22Å; F375-F403 HydrophobicContact CE2-CB 3.98Å; F375-F403 HydrophobicContact CE2-CD1 4.02Å; F375-F403 AromaticContact CE2-CD2 3.93Å; F375-F403 HydrophobicContact CE2-CD2 3.93Å; F375-F403 HydrophobicContact CE2-CE1 4.39Å; F375-F403 HydrophobicContact CE2-CE2 4.29Å; F375-F403 AromaticContact CE2-CG 3.73Å; F375-F403 HydrophobicContact CE2-CG 3.73Å; F375-F403 HydrophobicContact CE2-CZ 4.48Å; F375-F403 HydrophobicContact CZ-CB 4.03Å; F375-F403 HydrophobicContact CZ-CD1 4.26Å; F375-F403 HydrophobicContact CZ-CG 4.14Å; F399-F403 WeakPolarHBondContact O-CB 3.16Å; F399-F403 PolarHBondContact O-N 3.48Å; M400-F403 HydrophobicContact CE-CD1 3.82Å; M400-F403 HydrophobicContact CE-CE1 4.32Å; M400-F403 HydrophobicContact SD-CD1 4.26Å; F403-S406 PolarHBondContact O-OG 3.08Å; F403-N407 WeakPolarHBondContact O-CB 3.3Å; F403-N407 PolarHBondContact O-N 2.93Å; F403-N407 VanDerWaalsContact O-N 3.07Å
404	A	98.1	Very high	96.3	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-74.2	-45.7	-177.9	0	0	0	0	0	112.4	F337 M340 D341 M400 S406 N407 G408	F337-A404 HydrophobicContact CB-CB 4.36Å; F337-A404 HydrophobicContact CD2-CB 3.57Å; F337-A404 HydrophobicContact CE2-CB 4.11Å; F337-A404 HydrophobicContact CG-CB 4.13Å; F337-A404 WeakPolarHBondContact O-CB 3.48Å; M340-A404 HydrophobicContact CB-CB 3.56Å; D341-A404 WeakPolarHBondContact CA-O 3.31Å; M400-A404 WeakPolarHBondContact O-CB 3.37Å; M400-A404 PolarHBondContact O-N 3.12Å; A404-S406 VanDerWaalsContact C-N 3.32Å; A404-S406 PolarHBondContact O-N 3.5Å; A404-N407 WeakPolarHBondContact O-CB 3.41Å; A404-N407 PolarHBondContact O-N 3.26Å; A404-G408 PolarHBondContact O-N 3.46Å
405	I	97.8	Very high	96.3	Very high	48 Å²	48	25.8 Å²	25.8	25%	0.246	13%	0.13	C	C	.	.	H	α-helix	trans	-63.2	-41.2	178.7	-162.9	172.7	0	0	0	111.5	M340 L343 L401 L402 N407 G408 Y409	M340-I405 HydrophobicContact CB-CB 4.35Å; M340-I405 WeakPolarHBondContact O-CA 3.47Å; L343-I405 HydrophobicContact CD2-CD1 4.19Å; L343-I405 HydrophobicContact CG-CD1 4.5Å; L401-I405 VanDerWaalsContact O-CG2 3.31Å; L401-I405 WeakPolarHBondContact O-CG2 3.4Å; L401-I405 PolarHBondContact O-N 3.39Å; L401-I405 VanDerWaalsContact O-N 3.07Å; L402-I405 WeakPolarHBondContact O-CG2 3.46Å; I405-N407 VanDerWaalsContact C-N 3.28Å; I405-N407 PolarHBondContact O-N 2.89Å; I405-G408 PolarHBondContact O-N 3Å; I405-Y409 VanDerWaalsContact O-CB 3.28Å; I405-Y409 WeakPolarHBondContact O-CB 3.46Å; I405-Y409 PolarHBondContact O-N 3.32Å
406	S	97.8	Very high	96.2	Very high	29 Å²	29	21.1 Å²	21.1	20%	0.203	11%	0.112	C	C	.	.	H	α-helix	trans	-69.4	-26.7	175.6	56.4	0	0	0	0	112.2	R368 L402 F403 A404 L410	R368-S406 PolarHBondContact NH1-OG 3.06Å; L402-S406 WeakPolarHBondContact O-CB 3.44Å; L402-S406 PolarHBondContact O-N 3.17Å; L402-S406 VanDerWaalsContact O-N 3.17Å; L402-S406 PolarHBondContact O-OG 3.33Å; F403-S406 PolarHBondContact O-OG 3.08Å; A404-S406 VanDerWaalsContact C-N 3.32Å; A404-S406 PolarHBondContact O-N 3.5Å; S406-L410 VanDerWaalsContact O-CB 3.26Å; S406-L410 WeakPolarHBondContact O-CB 3.39Å; S406-L410 WeakPolarHBondContact O-CD1 3.49Å; S406-L410 WeakPolarHBondContact O-CG 3.49Å; S406-L410 PolarHBondContact O-N 3.37Å; S406-L410 VanDerWaalsContact O-N 3.1Å
407	N	97.6	Very high	96	Very high	3 Å²	3	21 Å²	21	2%	0.016	11%	0.112	C	C	.	.	H	α-helix	trans	-65.8	-56.8	174.3	-175.7	75.1	0	0	0	109.7	V300 T304 D341 F403 A404 I405 Y409 L410 V411	V300-N407 WeakPolarHBondContact CG1-OD1 3.15Å; T304-N407 WeakPolarHBondContact CB-OD1 3.18Å; T304-N407 PolarHBondContact OG1-OD1 3.05Å; D341-N407 PolarHBondContact OD1-ND2 3.28Å; F403-N407 WeakPolarHBondContact O-CB 3.3Å; F403-N407 PolarHBondContact O-N 2.93Å; F403-N407 VanDerWaalsContact O-N 3.07Å; A404-N407 WeakPolarHBondContact O-CB 3.41Å; A404-N407 PolarHBondContact O-N 3.26Å; I405-N407 VanDerWaalsContact C-N 3.28Å; I405-N407 PolarHBondContact O-N 2.89Å; N407-Y409 VanDerWaalsContact C-N 3.3Å; N407-Y409 PolarHBondContact O-N 3.42Å; N407-L410 PolarHBondContact O-N 3.04Å; N407-V411 WeakPolarHBondContact O-CB 3.18Å; N407-V411 VanDerWaalsContact O-CG2 3.23Å; N407-V411 WeakPolarHBondContact O-CG2 3.35Å; N407-V411 PolarHBondContact O-N 2.98Å
408	G	96.7	Very high	95.8	Very high	0 Å²	0	18.1 Å²	18.1	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-60.2	-42.8	-177	0	0	0	0	0	112.3	D341 R345 A404 I405 S412	D341-G408 WeakPolarHBondContact O-CA 2.89Å; D341-G408 WeakPolarHBondContact OD1-CA 3.45Å; D341-G408 PolarHBondContact OD1-N 3.4Å; R345-G408 WeakPolarHBondContact CG-O 3.47Å; A404-G408 PolarHBondContact O-N 3.46Å; I405-G408 PolarHBondContact O-N 3Å; G408-S412 WeakPolarHBondContact O-CB 3.04Å; G408-S412 PolarHBondContact O-N 2.92Å; G408-S412 PolarHBondContact O-OG 2.97Å
409	Y	96.9	Very high	95.4	Very high	33 Å²	33	15.1 Å²	15.1	13%	0.129	8%	0.079	C	C	.	.	H	α-helix	trans	-64.2	-51.5	179.1	-169.1	-101.5	0	0	0	112.5	G344 L347 T348 F351 W353 I405 N407 S412 L413	G344-Y409 WeakPolarHBondContact O-CA 3.48Å; G344-Y409 WeakPolarHBondContact O-CD2 3.26Å; L347-Y409 HydrophobicContact CB-CD2 4.08Å; L347-Y409 HydrophobicContact CB-CE2 4.26Å; L347-Y409 HydrophobicContact CD2-CD2 3.97Å; L347-Y409 HydrophobicContact CD2-CE2 3.96Å; L347-Y409 HydrophobicContact CG-CD2 4.19Å; L347-Y409 HydrophobicContact CG-CE2 3.99Å; T348-Y409 HydrophobicContact CG2-CD2 3.48Å; T348-Y409 VanDerWaalsContact CG2-CD2 3.48Å; T348-Y409 HydrophobicContact CG2-CE2 3.53Å; T348-Y409 HydrophobicContact CG2-CG 4.13Å; T348-Y409 WeakPolarHBondContact CG2-O 3.3Å; F351-Y409 PolarHBondContact O-OH 3Å; W353-Y409 PolarHBondContact N-OH 3.39Å; W353-Y409 WeakPolarHBondContact O-CE1 3.2Å; W353-Y409 PolarHBondContact O-OH 2.89Å; I405-Y409 VanDerWaalsContact O-CB 3.28Å; I405-Y409 WeakPolarHBondContact O-CB 3.46Å; I405-Y409 PolarHBondContact O-N 3.32Å; N407-Y409 VanDerWaalsContact C-N 3.3Å; N407-Y409 PolarHBondContact O-N 3.42Å; Y409-S412 PolarHBondContact O-N 3.23Å; Y409-L413 HydrophobicContact CE1-CD2 4.2Å; Y409-L413 WeakPolarHBondContact O-CB 3.2Å; Y409-L413 PolarHBondContact O-N 2.73Å
410	L	96.8	Very high	95	Very high	5 Å²	5	19.1 Å²	19.1	3%	0.026	9%	0.093	C	C	.	.	H	α-helix	trans	-71	-35.7	-175.8	-66.3	170.1	0	0	0	112.6	V300 L361 L364 V365 R368 S406 N407 T414	V300-L410 HydrophobicContact CG2-CB 3.96Å; V300-L410 HydrophobicContact CG2-CD1 4.31Å; L361-L410 HydrophobicContact CD1-CD2 3.84Å; L364-L410 HydrophobicContact CB-CD1 4.49Å; L364-L410 HydrophobicContact CB-CD2 4.25Å; L364-L410 HydrophobicContact CD1-CD2 4.47Å; V365-L410 HydrophobicContact CG2-CD1 4.2Å; R368-L410 HydrophobicContact CG-CD1 4.29Å; S406-L410 VanDerWaalsContact O-CB 3.26Å; S406-L410 WeakPolarHBondContact O-CB 3.39Å; S406-L410 WeakPolarHBondContact O-CD1 3.49Å; S406-L410 WeakPolarHBondContact O-CG 3.49Å; S406-L410 PolarHBondContact O-N 3.37Å; S406-L410 VanDerWaalsContact O-N 3.1Å; N407-L410 PolarHBondContact O-N 3.04Å; L410-T414 WeakPolarHBondContact O-CB 3.35Å; L410-T414 WeakPolarHBondContact O-CG2 3.32Å; L410-T414 PolarHBondContact O-N 3.08Å; L410-T414 PolarHBondContact O-OG1 3.05Å
411	V	95.8	Very high	94.6	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-61.8	-50.8	172.1	169.2	0	0	0	0	110.2	L297 V300 F301 N407 L413 T414 M415	L297-V411 HydrophobicContact CD1-CB 4.49Å; L297-V411 HydrophobicContact CD1-CG1 4.22Å; L297-V411 HydrophobicContact CD1-CG2 4.29Å; V300-V411 HydrophobicContact CG1-CG2 3.68Å; F301-V411 HydrophobicContact CD2-CG2 4.12Å; F301-V411 HydrophobicContact CE1-CG2 4.23Å; F301-V411 HydrophobicContact CE2-CB 4.28Å; F301-V411 HydrophobicContact CE2-CG1 3.75Å; F301-V411 HydrophobicContact CE2-CG2 3.48Å; F301-V411 VanDerWaalsContact CE2-CG2 3.48Å; F301-V411 HydrophobicContact CZ-CB 4.33Å; F301-V411 HydrophobicContact CZ-CG1 3.74Å; F301-V411 HydrophobicContact CZ-CG2 3.56Å; N407-V411 WeakPolarHBondContact O-CB 3.18Å; N407-V411 VanDerWaalsContact O-CG2 3.23Å; N407-V411 WeakPolarHBondContact O-CG2 3.35Å; N407-V411 PolarHBondContact O-N 2.98Å; V411-L413 VanDerWaalsContact C-N 3.33Å; V411-L413 PolarHBondContact O-N 2.84Å; V411-T414 PolarHBondContact O-OG1 3.33Å; V411-M415 WeakPolarHBondContact O-CB 3.33Å; V411-M415 WeakPolarHBondContact O-CG 3.44Å; V411-M415 PolarHBondContact O-N 3.45Å
412	S	94.8	Very high	94.1	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-65.6	-38.8	-179.4	-77.2	0	0	0	0	112.7	L164 R345 T348 G408 Y409 C416	L164-S412 WeakPolarHBondContact CB-OG 3.35Å; R345-S412 WeakPolarHBondContact CA-OG 3.25Å; R345-S412 WeakPolarHBondContact CB-OG 3.34Å; R345-S412 WeakPolarHBondContact CG-OG 3.11Å; T348-S412 WeakPolarHBondContact OG1-CB 3.33Å; G408-S412 WeakPolarHBondContact O-CB 3.04Å; G408-S412 PolarHBondContact O-N 2.92Å; G408-S412 PolarHBondContact O-OG 2.97Å; Y409-S412 PolarHBondContact O-N 3.23Å; S412-C416 WeakPolarHBondContact O-CB 3.5Å; S412-C416 PolarHBondContact O-N 2.87Å; S412-C416 PolarHBondContact O-SG 3.23Å
413	L	94.7	Very high	93.6	Very high	0 Å²	0	18.2 Å²	18.2	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-60.6	-55.5	177.8	-177.1	64.3	0	0	0	110.4	T348 L352 W353 L361 Y409 V411 M415 C416 L417	T348-L413 HydrophobicContact CG2-CB 4.3Å; L352-L413 HydrophobicContact CB-CD1 4.11Å; L352-L413 HydrophobicContact CG-CD1 4.38Å; W353-L413 WeakPolarHBondContact O-CD2 3.47Å; L361-L413 HydrophobicContact CD1-CD2 4.13Å; Y409-L413 HydrophobicContact CE1-CD2 4.2Å; Y409-L413 WeakPolarHBondContact O-CB 3.2Å; Y409-L413 PolarHBondContact O-N 2.73Å; V411-L413 VanDerWaalsContact C-N 3.33Å; V411-L413 PolarHBondContact O-N 2.84Å; L413-M415 VanDerWaalsContact C-N 3.34Å; L413-M415 PolarHBondContact O-N 3.27Å; L413-C416 PolarHBondContact O-N 3.06Å; L413-L417 HydrophobicContact CD1-CD1 3.78Å; L413-L417 HydrophobicContact CD1-CD2 4.21Å; L413-L417 HydrophobicContact CD1-CG 3.96Å; L413-L417 HydrophobicContact CD2-CD1 4.39Å; L413-L417 HydrophobicContact CG-CD1 3.69Å; L413-L417 HydrophobicContact CG-CG 4.2Å; L413-L417 VanDerWaalsContact O-CG 3.28Å; L413-L417 WeakPolarHBondContact O-CG 3.41Å; L413-L417 PolarHBondContact O-N 3.07Å
414	T	94.4	Very high	92.9	Very high	0 Å²	0	21.5 Å²	21.5	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-58.8	-42.2	179.8	49	0	0	0	0	112.7	T293 C296 L361 L410 V411 C416 L417 A418 M434	T293-T414 HydrophobicContact CG2-CG2 4.03Å; T293-T414 WeakPolarHBondContact CG2-O 3.27Å; C296-T414 HydrophobicContact CB-CG2 3.97Å; L361-T414 HydrophobicContact CD1-CG2 4.13Å; L361-T414 HydrophobicContact CD2-CG2 4.1Å; L410-T414 WeakPolarHBondContact O-CB 3.35Å; L410-T414 WeakPolarHBondContact O-CG2 3.32Å; L410-T414 PolarHBondContact O-N 3.08Å; L410-T414 PolarHBondContact O-OG1 3.05Å; V411-T414 PolarHBondContact O-OG1 3.33Å; T414-C416 VanDerWaalsContact C-N 3.26Å; T414-C416 PolarHBondContact O-N 3.2Å; T414-L417 PolarHBondContact O-N 3.44Å; T414-A418 PolarHBondContact O-N 3.45Å; T414-A418 VanDerWaalsContact O-N 3.1Å; T414-M434 WeakPolarHBondContact O-CE 3.33Å
415	M	92.4	Very high	92.2	Very high	6 Å²	6	25.1 Å²	25.1	3%	0.03	13%	0.126	C	C	.	.	H	α-helix	trans	-62	-30.9	175.6	-77.7	-67.4	-170.4	0	0	113.4	F149 L164 L297 V411 L413 P419 M434 L438	F149-M415 HydrophobicContact CD1-SD 4.47Å; F149-M415 HydrophobicContact CE1-SD 4.28Å; F149-M415 HydrophobicContact CE2-CE 4.48Å; F149-M415 HydrophobicContact CZ-CE 4.48Å; F149-M415 HydrophobicContact CZ-SD 4.48Å; L164-M415 HydrophobicContact CD1-CB 3.8Å; L164-M415 HydrophobicContact CD1-CG 4.44Å; L164-M415 HydrophobicContact CD2-CG 4.37Å; L297-M415 HydrophobicContact CD1-CE 4.44Å; L297-M415 HydrophobicContact CD2-CE 3.66Å; L297-M415 HydrophobicContact CD2-SD 4.23Å; V411-M415 WeakPolarHBondContact O-CB 3.33Å; V411-M415 WeakPolarHBondContact O-CG 3.44Å; V411-M415 PolarHBondContact O-N 3.45Å; L413-M415 VanDerWaalsContact C-N 3.34Å; L413-M415 PolarHBondContact O-N 3.27Å; M415-P419 VanDerWaalsContact O-CD 3.29Å; M415-P419 WeakPolarHBondContact O-CD 3.46Å; M415-M434 HydrophobicContact CE-CB 4.33Å; M415-M434 HydrophobicContact SD-CB 3.7Å; M415-M434 HydrophobicContact SD-CE 4.4Å; M415-L438 HydrophobicContact CE-CB 3.81Å; M415-L438 HydrophobicContact CE-CD1 3.34Å; M415-L438 HydrophobicContact CE-CG 4.21Å
416	C	91.1	Very high	91.6	Very high	3 Å²	3	23.2 Å²	23.2	2%	0.02	12%	0.116	C	C	.	.	H	α-helix	trans	-86.3	-30.7	178.7	-66.7	0	0	0	0	113.5	T161 L352 S412 L413 T414	T161-C416 WeakPolarHBondContact CG2-SG 3.37Å; L352-C416 HydrophobicContact CD2-CB 3.97Å; S412-C416 WeakPolarHBondContact O-CB 3.5Å; S412-C416 PolarHBondContact O-N 2.87Å; S412-C416 PolarHBondContact O-SG 3.23Å; L413-C416 PolarHBondContact O-N 3.06Å; T414-C416 VanDerWaalsContact C-N 3.26Å; T414-C416 PolarHBondContact O-N 3.2Å
417	L	91.2	Very high	91.1	Very high	1 Å²	1	25.7 Å²	25.7	1%	0.005	12%	0.121	C	C	.	.	H	α-helix	trans	-77.9	-37.1	-179.7	-66.6	-180	0	0	0	112.2	T293 L352 E356 L361 L413 T414 R420 Q421	T293-L417 HydrophobicContact CG2-CB 4.46Å; L352-L417 HydrophobicContact CD2-CD2 4.34Å; E356-L417 HydrophobicContact CG-CB 3.93Å; E356-L417 HydrophobicContact CG-CD1 4.2Å; E356-L417 HydrophobicContact CG-CD2 3.41Å; E356-L417 VanDerWaalsContact CG-CD2 3.41Å; E356-L417 HydrophobicContact CG-CG 3.98Å; L361-L417 HydrophobicContact CD2-CD1 4.28Å; L413-L417 HydrophobicContact CD1-CD1 3.78Å; L413-L417 HydrophobicContact CD1-CD2 4.21Å; L413-L417 HydrophobicContact CD1-CG 3.96Å; L413-L417 HydrophobicContact CD2-CD1 4.39Å; L413-L417 HydrophobicContact CG-CD1 3.69Å; L413-L417 HydrophobicContact CG-CG 4.2Å; L413-L417 VanDerWaalsContact O-CG 3.28Å; L413-L417 WeakPolarHBondContact O-CG 3.41Å; L413-L417 PolarHBondContact O-N 3.07Å; T414-L417 PolarHBondContact O-N 3.44Å; L417-R420 WeakPolarHBondContact O-CB 3.3Å; L417-R420 PolarHBondContact O-N 3Å; L417-Q421 PolarHBondContact O-N 3Å
418	A	91.5	Very high	90.5	Very high	0 Å²	0	27.3 Å²	27.3	0%	0	13%	0.128	C	C	.	.	G	3₁₀ helix	trans	-58.4	-43.4	-175.4	0	0	0	0	0	114.9	I290 T293 T414 R420 Q421 M434	I290-A418 HydrophobicContact CB-CB 4.35Å; I290-A418 HydrophobicContact CG2-CB 4.25Å; I290-A418 WeakPolarHBondContact CG2-O 3.29Å; T293-A418 HydrophobicContact CG2-CB 3.99Å; T414-A418 PolarHBondContact O-N 3.45Å; T414-A418 VanDerWaalsContact O-N 3.1Å; A418-R420 PolarHBondContact O-N 3.31Å; A418-Q421 PolarHBondContact O-N 3.46Å; A418-M434 HydrophobicContact CB-CE 3.7Å; A418-M434 HydrophobicContact CB-CG 3.47Å; A418-M434 VanDerWaalsContact CB-CG 3.47Å; A418-M434 HydrophobicContact CB-SD 3.55Å; A418-M434 VanDerWaalsContact CB-SD 3.55Å
419	P	87.7	Confident	90	Very high	11 Å²	11	27.5 Å²	27.5	7%	0.071	13%	0.129	C	C	.	.	G	3₁₀ helix	trans	-69.3	-13.8	176.3	-21.2	34.5	0	0	0	114.7	M415 V422 R427	M415-P419 VanDerWaalsContact O-CD 3.29Å; M415-P419 WeakPolarHBondContact O-CD 3.46Å; P419-V422 WeakPolarHBondContact O-CG2 3.44Å; P419-R427 HydrophobicContact CB-CB 4.35Å; P419-R427 HydrophobicContact CB-CG 4.47Å; P419-R427 WeakPolarHBondContact O-CD 3.42Å; P419-R427 VanDerWaalsContact O-CG 3.32Å; P419-R427 WeakPolarHBondContact O-CG 3.49Å; P419-R427 PolarHBondContact O-NE 2.92Å
420	R	87.8	Confident	89.7	Confident	108 Å²	108	25.9 Å²	25.9	41%	0.408	12%	0.123	S	C	.	.	G	3₁₀ helix	trans	-85.5	-24.5	178	-68.1	175.8	171	-163.7	-2.5	112.5	S157 E356 L417 A418 V422	S157-R420 PolarHBondContact OG-NH2 2.89Å; E356-R420 WeakPolarHBondContact OE1-CB 3.21Å; E356-R420 WeakPolarHBondContact OE1-CD 3.26Å; L417-R420 WeakPolarHBondContact O-CB 3.3Å; L417-R420 PolarHBondContact O-N 3Å; A418-R420 PolarHBondContact O-N 3.31Å; R420-V422 PolarHBondContact O-N 3.25Å
421	Q	88.8	Confident	89.3	Confident	52 Å²	52	25.8 Å²	25.8	24%	0.243	12%	0.123	C	C	.	.	S	Bend	trans	-74.3	-2.8	175.8	-64	173.3	-1.5	0	0	113.8	I290 T293 E356 L417 A418	I290-Q421 HydrophobicContact CG2-CB 4.34Å; T293-Q421 PolarHBondContact OG1-NE2 3.17Å; T293-Q421 PolarHBondContact OG1-OE1 3.2Å; E356-Q421 HydrophobicContact CB-CG 4.43Å; E356-Q421 WeakPolarHBondContact OE2-CG 3.27Å; L417-Q421 PolarHBondContact O-N 3Å; A418-Q421 PolarHBondContact O-N 3.46Å
422	V	88.9	Confident	88.9	Confident	9 Å²	9	26.1 Å²	26.1	6%	0.055	13%	0.126	C	C	.	.	S	Bend	trans	-128.1	161	-173.4	-54.3	0	0	0	0	111.7	V286 K289 I290 P419 R420 E426 R427 A430	V286-V422 HydrophobicContact CG1-CG1 4.15Å; K289-V422 HydrophobicContact CB-CG1 3.99Å; K289-V422 HydrophobicContact CD-CG1 4.14Å; I290-V422 HydrophobicContact CG2-CG1 3.54Å; P419-V422 WeakPolarHBondContact O-CG2 3.44Å; R420-V422 PolarHBondContact O-N 3.25Å; V422-E426 HydrophobicContact CB-CB 3.92Å; V422-E426 HydrophobicContact CG2-CB 3.99Å; V422-R427 HydrophobicContact CG2-CB 4.43Å; V422-R427 HydrophobicContact CG2-CG 3.9Å; V422-A430 HydrophobicContact CG1-CB 4.21Å; V422-A430 HydrophobicContact CG2-CB 3.73Å
423	L	87.3	Confident	88.7	Confident	75 Å²	75	26.6 Å²	26.6	39%	0.393	13%	0.128	S	C	.	.			trans	-66.4	153.7	179.9	-64.8	171.8	0	0	0	110.7	H425 E426 R427	L423-H425 PolarHBondContact O-N 3.5Å; L423-H425 VanDerWaalsContact O-N 3.08Å; L423-E426 HydrophobicContact CB-CG 4.19Å; L423-E426 PolarHBondContact N-OE2 3.32Å; L423-E426 WeakPolarHBondContact O-CA 3.38Å; L423-E426 WeakPolarHBondContact O-CB 3.11Å; L423-E426 PolarHBondContact O-N 2.78Å; L423-R427 WeakPolarHBondContact O-CG 3.38Å; L423-R427 PolarHBondContact O-N 2.91Å
424	P	83	Confident	88.6	Confident	69 Å²	69	26.6 Å²	26.6	45%	0.448	13%	0.128	S	C	.	.	T	Hydrogen-bonded Turn	trans	-51.9	-36.6	-177.6	-29.8	36.3	0	0	0	114.9	E426	P424-E426 VanDerWaalsContact C-N 3.3Å; P424-E426 PolarHBondContact O-N 3.21Å
425	H	82.3	Confident	88.5	Confident	75 Å²	75	26.7 Å²	26.7	35%	0.347	13%	0.129	S	C	.	.	T	Hydrogen-bonded Turn	trans	-77.1	-13.8	178.7	71	-97.5	0	0	0	113.7	L423	L423-H425 PolarHBondContact O-N 3.5Å; L423-H425 VanDerWaalsContact O-N 3.08Å
426	E	86.8	Confident	88.5	Confident	9 Å²	9	28 Å²	28	4%	0.042	13%	0.134	C	C	.	.	T	Hydrogen-bonded Turn	trans	-95.5	-13.3	178	-62.6	175.8	141.3	0	0	112.7	P281 V286 K289 V422 L423 P424 E428 V429 A430	P281-E426 HydrophobicContact CB-CG 4.12Å; V286-E426 HydrophobicContact CG2-CB 3.84Å; V286-E426 HydrophobicContact CG2-CG 3.9Å; K289-E426 IonicContact NZ-OE1 2.89Å; K289-E426 PolarHBondContact NZ-OE1 3.29Å; K289-E426 IonicContact NZ-OE2 2.72Å; K289-E426 PolarHBondContact NZ-OE2 2.85Å; V422-E426 HydrophobicContact CB-CB 3.92Å; V422-E426 HydrophobicContact CG2-CB 3.99Å; L423-E426 HydrophobicContact CB-CG 4.19Å; L423-E426 PolarHBondContact N-OE2 3.32Å; L423-E426 WeakPolarHBondContact O-CA 3.38Å; L423-E426 WeakPolarHBondContact O-CB 3.11Å; L423-E426 PolarHBondContact O-N 2.78Å; P424-E426 VanDerWaalsContact C-N 3.3Å; P424-E426 PolarHBondContact O-N 3.21Å; E426-E428 VanDerWaalsContact C-N 3.35Å; E426-E428 PolarHBondContact O-N 3.13Å; E426-V429 WeakPolarHBondContact O-CB 3.47Å; E426-V429 PolarHBondContact O-N 3.5Å; E426-A430 PolarHBondContact O-N 2.67Å
427	R	86.3	Confident	88.7	Confident	81 Å²	81	29 Å²	29	31%	0.306	14%	0.139	S	C	.	.	H	α-helix	trans	-61.8	-36.4	-171.2	-62.5	-169.2	177.5	155.4	-2	114.7	G153 P419 V422 L423 V429 A430 G431	G153-R427 VanDerWaalsContact O-CB 3.24Å; G153-R427 WeakPolarHBondContact O-CB 3.27Å; G153-R427 WeakPolarHBondContact O-CD 3.2Å; P419-R427 HydrophobicContact CB-CB 4.35Å; P419-R427 HydrophobicContact CB-CG 4.47Å; P419-R427 WeakPolarHBondContact O-CD 3.42Å; P419-R427 VanDerWaalsContact O-CG 3.32Å; P419-R427 WeakPolarHBondContact O-CG 3.49Å; P419-R427 PolarHBondContact O-NE 2.92Å; V422-R427 HydrophobicContact CG2-CB 4.43Å; V422-R427 HydrophobicContact CG2-CG 3.9Å; L423-R427 WeakPolarHBondContact O-CG 3.38Å; L423-R427 PolarHBondContact O-N 2.91Å; R427-V429 VanDerWaalsContact C-N 3.3Å; R427-V429 PolarHBondContact O-N 3.32Å; R427-A430 PolarHBondContact O-N 3.06Å; R427-G431 PolarHBondContact O-N 2.81Å
428	E	85.3	Confident	88.9	Confident	37 Å²	37	29.5 Å²	29.5	17%	0.173	14%	0.141	C	C	.	.	H	α-helix	trans	-61.6	-42.8	175.5	-174.9	-177.3	169.4	0	0	110.6	R98 G150 T154 E426 G431 A432	R98-E428 IonicContact NH2-OE1 3.71Å; G150-E428 WeakPolarHBondContact CA-O 3.37Å; G150-E428 WeakPolarHBondContact O-CA 3.28Å; T154-E428 HydrophobicContact CG2-CB 4.48Å; E426-E428 VanDerWaalsContact C-N 3.35Å; E426-E428 PolarHBondContact O-N 3.13Å; E428-G431 PolarHBondContact O-N 3.39Å; E428-A432 PolarHBondContact O-N 2.87Å; E428-A432 VanDerWaalsContact O-N 3.08Å
429	V	86.6	Confident	89	Confident	3 Å²	3	29.5 Å²	29.5	2%	0.018	14%	0.141	C	C	.	.	H	α-helix	trans	-68	-42.1	178.2	-176.7	0	0	0	0	110.6	Y90 P281 V283 V286 E426 R427 G431 A432 L433	Y90-V429 HydrophobicContact CE1-CG2 4.26Å; Y90-V429 HydrophobicContact CE2-CG2 4.3Å; Y90-V429 WeakPolarHBondContact OH-CG2 3.47Å; P281-V429 HydrophobicContact CG-CG2 4.24Å; V283-V429 HydrophobicContact CG2-CG1 4.18Å; V286-V429 HydrophobicContact CB-CG1 4.33Å; V286-V429 HydrophobicContact CG1-CB 4.44Å; V286-V429 HydrophobicContact CG1-CG1 4.26Å; V286-V429 HydrophobicContact CG2-CB 4.46Å; V286-V429 HydrophobicContact CG2-CG1 4.28Å; E426-V429 WeakPolarHBondContact O-CB 3.47Å; E426-V429 PolarHBondContact O-N 3.5Å; R427-V429 VanDerWaalsContact C-N 3.3Å; R427-V429 PolarHBondContact O-N 3.32Å; V429-G431 PolarHBondContact O-N 3.37Å; V429-A432 PolarHBondContact O-N 3.12Å; V429-L433 HydrophobicContact CG1-CD1 4.17Å; V429-L433 HydrophobicContact CG1-CG 4.37Å; V429-L433 WeakPolarHBondContact O-CB 3.35Å; V429-L433 WeakPolarHBondContact O-CG 3.48Å; V429-L433 PolarHBondContact O-N 3Å
430	A	90.3	Very high	89.4	Confident	0 Å²	0	31.4 Å²	31.4	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-60.4	-45.1	176.6	0	0	0	0	0	112	V286 I290 V422 E426 R427 A432 L433 M434	V286-A430 HydrophobicContact CG1-CB 3.86Å; I290-A430 HydrophobicContact CD1-CB 4.31Å; I290-A430 HydrophobicContact CG2-CB 4.45Å; V422-A430 HydrophobicContact CG1-CB 4.21Å; V422-A430 HydrophobicContact CG2-CB 3.73Å; E426-A430 PolarHBondContact O-N 2.67Å; R427-A430 PolarHBondContact O-N 3.06Å; A430-A432 PolarHBondContact O-N 2.93Å; A430-L433 PolarHBondContact O-N 3.22Å; A430-M434 VanDerWaalsContact O-CG 3.26Å; A430-M434 WeakPolarHBondContact O-CG 3.5Å; A430-M434 PolarHBondContact O-N 3.34Å
431	G	89.1	Confident	89.8	Confident	3 Å²	3	26.3 Å²	26.3	3%	0.031	13%	0.131	C	C	.	.	H	α-helix	trans	-61.7	-42	175.7	0	0	0	0	0	113.2	R427 E428 V429 M434 T435	R427-G431 PolarHBondContact O-N 2.81Å; E428-G431 PolarHBondContact O-N 3.39Å; V429-G431 PolarHBondContact O-N 3.37Å; G431-M434 PolarHBondContact O-N 3.1Å; G431-T435 PolarHBondContact O-N 2.86Å; G431-T435 PolarHBondContact O-OG1 2.88Å; G431-T435 VanDerWaalsContact O-OG1 3.07Å
432	A	86.9	Confident	90.1	Very high	6 Å²	6	25.1 Å²	25.1	5%	0.05	13%	0.127	C	C	.	.	H	α-helix	trans	-63.5	-45.6	175.3	0	0	0	0	0	112.1	E428 V429 A430 M434 T435 F436	E428-A432 PolarHBondContact O-N 2.87Å; E428-A432 VanDerWaalsContact O-N 3.08Å; V429-A432 PolarHBondContact O-N 3.12Å; A430-A432 PolarHBondContact O-N 2.93Å; A432-M434 VanDerWaalsContact C-N 3.35Å; A432-M434 PolarHBondContact O-N 3.05Å; A432-T435 WeakPolarHBondContact O-CB 3.4Å; A432-T435 PolarHBondContact O-N 3.47Å; A432-T435 VanDerWaalsContact O-N 3.15Å; A432-F436 PolarHBondContact O-N 3.41Å
433	L	90.4	Very high	90.4	Very high	10 Å²	10	25.6 Å²	25.6	5%	0.052	13%	0.13	C	C	.	.	H	α-helix	trans	-60.8	-41.9	176.3	-78.1	176.6	0	0	0	112.2	V283 V286 F287 I290 V429 A430 T435 F436 F437	V283-L433 HydrophobicContact CG1-CD1 4.07Å; V283-L433 HydrophobicContact CG1-CD2 3.82Å; V283-L433 HydrophobicContact CG1-CG 4.31Å; V286-L433 HydrophobicContact CB-CD1 4.22Å; V286-L433 HydrophobicContact CG1-CD1 3.99Å; F287-L433 HydrophobicContact CB-CD1 4.25Å; I290-L433 HydrophobicContact CD1-CB 4.02Å; I290-L433 HydrophobicContact CD1-CD1 4.24Å; V429-L433 HydrophobicContact CG1-CD1 4.17Å; V429-L433 HydrophobicContact CG1-CG 4.37Å; V429-L433 WeakPolarHBondContact O-CB 3.35Å; V429-L433 WeakPolarHBondContact O-CG 3.48Å; V429-L433 PolarHBondContact O-N 3Å; A430-L433 PolarHBondContact O-N 3.22Å; L433-T435 PolarHBondContact O-N 3.26Å; L433-F436 WeakPolarHBondContact O-CA 3.3Å; L433-F436 WeakPolarHBondContact O-CB 3.44Å; L433-F436 PolarHBondContact O-N 3.17Å; L433-F437 WeakPolarHBondContact O-CD2 3.25Å; L433-F437 PolarHBondContact O-N 2.86Å
434	M	92.9	Very high	90.8	Very high	1 Å²	1	24.3 Å²	24.3	1%	0.005	13%	0.127	C	C	.	.	H	α-helix	trans	-61.1	-33.4	176.7	-73	-62.2	-76.7	0	0	112.4	I290 T293 A294 L297 T414 M415 A418 A430 G431 A432 F437 L438	I290-M434 HydrophobicContact CD1-CG 4.25Å; I290-M434 HydrophobicContact CD1-SD 4.23Å; T293-M434 HydrophobicContact CG2-CE 4.03Å; A294-M434 HydrophobicContact CB-SD 4.01Å; L297-M434 HydrophobicContact CB-CE 4.21Å; L297-M434 HydrophobicContact CD2-CE 3.54Å; L297-M434 WeakPolarHBondContact CD2-O 3.47Å; L297-M434 HydrophobicContact CD2-SD 4.33Å; L297-M434 HydrophobicContact CG-CE 4.47Å; T414-M434 WeakPolarHBondContact O-CE 3.33Å; M415-M434 HydrophobicContact CE-CB 4.33Å; M415-M434 HydrophobicContact SD-CB 3.7Å; M415-M434 HydrophobicContact SD-CE 4.4Å; A418-M434 HydrophobicContact CB-CE 3.7Å; A418-M434 HydrophobicContact CB-CG 3.47Å; A418-M434 VanDerWaalsContact CB-CG 3.47Å; A418-M434 HydrophobicContact CB-SD 3.55Å; A418-M434 VanDerWaalsContact CB-SD 3.55Å; A430-M434 VanDerWaalsContact O-CG 3.26Å; A430-M434 WeakPolarHBondContact O-CG 3.5Å; A430-M434 PolarHBondContact O-N 3.34Å; G431-M434 PolarHBondContact O-N 3.1Å; A432-M434 VanDerWaalsContact C-N 3.35Å; A432-M434 PolarHBondContact O-N 3.05Å; M434-F437 PolarHBondContact O-N 3.35Å; M434-L438 WeakPolarHBondContact O-CB 3.5Å; M434-L438 PolarHBondContact O-N 3.25Å
435	T	92	Very high	91.3	Very high	1 Å²	1	21 Å²	21	1%	0.006	11%	0.106	C	C	.	.	H	α-helix	trans	-67.4	-37.5	174.2	-49.8	0	0	0	0	111.8	T83 Q145 F149 G431 A432 L433 L438 A439	T83-T435 HydrophobicContact CG2-CG2 3.86Å; Q145-T435 HydrophobicContact CB-CG2 3.85Å; F149-T435 WeakPolarHBondContact CB-OG1 3.34Å; F149-T435 HydrophobicContact CD2-CG2 4.44Å; F149-T435 WeakPolarHBondContact CD2-OG1 3.4Å; G431-T435 PolarHBondContact O-N 2.86Å; G431-T435 PolarHBondContact O-OG1 2.88Å; G431-T435 VanDerWaalsContact O-OG1 3.07Å; A432-T435 WeakPolarHBondContact O-CB 3.4Å; A432-T435 PolarHBondContact O-N 3.47Å; A432-T435 VanDerWaalsContact O-N 3.15Å; L433-T435 PolarHBondContact O-N 3.26Å; T435-L438 WeakPolarHBondContact O-CB 3.4Å; T435-L438 PolarHBondContact O-N 2.94Å; T435-A439 PolarHBondContact O-N 3.36Å
436	F	93.1	Very high	91.8	Very high	33 Å²	33	17.8 Å²	17.8	15%	0.145	9%	0.092	C	C	.	.	H	α-helix	trans	-63	-45.7	171.8	165.3	-101.4	0	0	0	111.9	L80 L84 A432 L433 L438 A439 L440	L80-F436 HydrophobicContact CD1-CE2 4.02Å; L80-F436 HydrophobicContact CG-CE2 4.2Å; L84-F436 HydrophobicContact CB-CD2 3.67Å; L84-F436 HydrophobicContact CB-CE2 3.77Å; L84-F436 HydrophobicContact CD1-CD2 4.13Å; L84-F436 HydrophobicContact CD1-CE2 3.97Å; L84-F436 HydrophobicContact CD1-CZ 4.2Å; L84-F436 HydrophobicContact CD2-CE2 4.4Å; L84-F436 HydrophobicContact CG-CD2 4.46Å; L84-F436 HydrophobicContact CG-CE2 4.26Å; A432-F436 PolarHBondContact O-N 3.41Å; L433-F436 WeakPolarHBondContact O-CA 3.3Å; L433-F436 WeakPolarHBondContact O-CB 3.44Å; L433-F436 PolarHBondContact O-N 3.17Å; F436-L438 VanDerWaalsContact C-N 3.31Å; F436-L438 PolarHBondContact O-N 3.48Å; F436-A439 WeakPolarHBondContact O-CB 3.32Å; F436-A439 PolarHBondContact O-N 3.41Å; F436-A439 VanDerWaalsContact O-N 3.13Å; F436-L440 PolarHBondContact O-N 3.21Å
437	F	95.3	Very high	92	Very high	26 Å²	26	21.3 Å²	21.3	11%	0.114	12%	0.118	C	C	.	.	H	α-helix	trans	-66.3	-32.2	177.5	-75.7	-67.8	0	0	0	113.1	F287 A294 L297 V298 L433 M434 L440 G441	F287-F437 AromaticContact CD2-CE2 3.68Å; F287-F437 HydrophobicContact CD2-CE2 3.68Å; F287-F437 AromaticContact CD2-CZ 3.49Å; F287-F437 HydrophobicContact CD2-CZ 3.49Å; F287-F437 VanDerWaalsContact CD2-CZ 3.49Å; F287-F437 HydrophobicContact CE2-CE1 4.07Å; F287-F437 AromaticContact CE2-CE2 3.87Å; F287-F437 HydrophobicContact CE2-CE2 3.87Å; F287-F437 AromaticContact CE2-CZ 3.25Å; F287-F437 HydrophobicContact CE2-CZ 3.25Å; F287-F437 HydrophobicContact CZ-CZ 4.32Å; A294-F437 HydrophobicContact CB-CB 4.2Å; A294-F437 HydrophobicContact CB-CD1 4.18Å; A294-F437 HydrophobicContact CB-CD2 3.52Å; A294-F437 HydrophobicContact CB-CE2 3.92Å; A294-F437 HydrophobicContact CB-CG 3.69Å; A294-F437 HydrophobicContact CB-CZ 4.42Å; L297-F437 HydrophobicContact CD2-CB 4.48Å; V298-F437 HydrophobicContact CG2-CB 3.9Å; V298-F437 HydrophobicContact CG2-CD1 3.75Å; V298-F437 HydrophobicContact CG2-CG 4.3Å; V298-F437 VanDerWaalsContact CG2-O 3.28Å; V298-F437 WeakPolarHBondContact CG2-O 3.29Å; L433-F437 WeakPolarHBondContact O-CD2 3.25Å; L433-F437 PolarHBondContact O-N 2.86Å; M434-F437 PolarHBondContact O-N 3.35Å; F437-L440 HydrophobicContact CD1-CD2 4.08Å; F437-L440 HydrophobicContact CE1-CD2 4.36Å; F437-L440 PolarHBondContact O-N 3.48Å; F437-G441 PolarHBondContact O-N 2.77Å
438	L	94.6	Very high	92.4	Very high	10 Å²	10	20.3 Å²	20.3	5%	0.052	12%	0.118	C	C	.	.	H	α-helix	trans	-58.2	-51.7	167.5	-177.4	149.7	0	0	0	110.9	L297 F301 M415 M434 T435 F436 L440 G441 L442	L297-L438 HydrophobicContact CD2-CB 4.09Å; F301-L438 HydrophobicContact CD2-CD1 4.39Å; F301-L438 HydrophobicContact CD2-CG 3.92Å; F301-L438 HydrophobicContact CE2-CB 4.35Å; F301-L438 HydrophobicContact CE2-CD1 3.46Å; F301-L438 VanDerWaalsContact CE2-CD1 3.46Å; F301-L438 HydrophobicContact CE2-CG 3.46Å; F301-L438 VanDerWaalsContact CE2-CG 3.46Å; F301-L438 HydrophobicContact CZ-CD1 3.72Å; F301-L438 HydrophobicContact CZ-CG 3.93Å; M415-L438 HydrophobicContact CE-CB 3.81Å; M415-L438 HydrophobicContact CE-CD1 3.34Å; M415-L438 HydrophobicContact CE-CG 4.21Å; M434-L438 WeakPolarHBondContact O-CB 3.5Å; M434-L438 PolarHBondContact O-N 3.25Å; T435-L438 WeakPolarHBondContact O-CB 3.4Å; T435-L438 PolarHBondContact O-N 2.94Å; F436-L438 VanDerWaalsContact C-N 3.31Å; F436-L438 PolarHBondContact O-N 3.48Å; L438-L440 VanDerWaalsContact C-N 3.3Å; L438-L440 PolarHBondContact O-N 3.36Å; L438-G441 PolarHBondContact O-N 3.45Å; L438-L442 HydrophobicContact CD2-CD1 3.56Å; L438-L442 HydrophobicContact CD2-CG 4.13Å; L438-L442 WeakPolarHBondContact O-CG 3.39Å; L438-L442 PolarHBondContact O-N 2.96Å
439	A	94.3	Very high	92.7	Very high	1 Å²	1	19.1 Å²	19.1	1%	0.008	11%	0.114	C	C	.	.	H	α-helix	trans	-61.8	-37.1	179.4	0	0	0	0	0	112.6	L79 L80 T83 T435 F436 L442 S443	L79-A439 HydrophobicContact CD2-CB 4.2Å; L79-A439 HydrophobicContact CG-CB 3.86Å; L80-A439 HydrophobicContact CD1-CB 4.46Å; T83-A439 HydrophobicContact CG2-CB 4.19Å; T435-A439 PolarHBondContact O-N 3.36Å; F436-A439 WeakPolarHBondContact O-CB 3.32Å; F436-A439 PolarHBondContact O-N 3.41Å; F436-A439 VanDerWaalsContact O-N 3.13Å; A439-L442 PolarHBondContact O-N 3.18Å; A439-S443 WeakPolarHBondContact O-CB 3.4Å; A439-S443 PolarHBondContact O-N 2.91Å; A439-S443 PolarHBondContact O-OG 3.01Å
440	L	95.6	Very high	92.7	Very high	51 Å²	51	23.1 Å²	23.1	27%	0.267	13%	0.131	S	C	.	.	H	α-helix	trans	-61.8	-47.7	173.2	-177.5	64.6	0	0	0	111.3	L80 V298 F436 F437 L438 L442 S443 C444	L80-L440 HydrophobicContact CD1-CB 3.95Å; L80-L440 HydrophobicContact CD1-CD1 3.98Å; V298-L440 HydrophobicContact CG2-CB 4.44Å; V298-L440 HydrophobicContact CG2-CD2 4.12Å; V298-L440 HydrophobicContact CG2-CG 4.47Å; F436-L440 PolarHBondContact O-N 3.21Å; F437-L440 HydrophobicContact CD1-CD2 4.08Å; F437-L440 HydrophobicContact CE1-CD2 4.36Å; F437-L440 PolarHBondContact O-N 3.48Å; L438-L440 VanDerWaalsContact C-N 3.3Å; L438-L440 PolarHBondContact O-N 3.36Å; L440-L442 PolarHBondContact O-N 2.7Å; L440-S443 WeakPolarHBondContact O-CB 3.44Å; L440-S443 PolarHBondContact O-N 2.98Å; L440-C444 PolarHBondContact O-N 2.74Å; L440-C444 PolarHBondContact O-SG 3.42Å; L440-C444 VanDerWaalsContact O-SG 3.34Å
441	G	96.8	Very high	92.7	Very high	0 Å²	0	27.7 Å²	27.7	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-60.5	-42.4	176.3	0	0	0	0	0	113.2	V298 F301 T302 F437 L438 S443 G445	V298-G441 WeakPolarHBondContact O-CA 3.33Å; F301-G441 CarbonylContact C-O 3.59Å; T302-G441 WeakPolarHBondContact CA-O 3.26Å; T302-G441 PolarHBondContact N-O 3.42Å; F437-G441 PolarHBondContact O-N 2.77Å; L438-G441 PolarHBondContact O-N 3.45Å; G441-S443 VanDerWaalsContact C-N 3.33Å; G441-S443 PolarHBondContact O-N 2.8Å; G441-G445 PolarHBondContact O-N 3.29Å
442	L	94.4	Very high	92.7	Very high	28 Å²	28	29.3 Å²	29.3	15%	0.147	16%	0.161	C	C	.	.	H	α-helix	trans	-60	-43.5	174.1	-68.4	177	0	0	0	111.7	L79 F301 L305 L438 A439 L440 A446	L79-L442 HydrophobicContact CD2-CD1 3.9Å; F301-L442 HydrophobicContact CB-CD2 4.38Å; F301-L442 HydrophobicContact CD1-CD2 3.46Å; F301-L442 VanDerWaalsContact CD1-CD2 3.46Å; F301-L442 HydrophobicContact CD1-CG 4.24Å; F301-L442 HydrophobicContact CE1-CD2 3.92Å; F301-L442 HydrophobicContact CG-CD2 4.09Å; F301-L442 HydrophobicContact CG-CG 4.45Å; L305-L442 HydrophobicContact CD1-CD2 4.33Å; L305-L442 HydrophobicContact CD2-CD2 3.65Å; L305-L442 HydrophobicContact CG-CD2 3.65Å; L438-L442 HydrophobicContact CD2-CD1 3.56Å; L438-L442 HydrophobicContact CD2-CG 4.13Å; L438-L442 WeakPolarHBondContact O-CG 3.39Å; L438-L442 PolarHBondContact O-N 2.96Å; A439-L442 PolarHBondContact O-N 3.18Å; L440-L442 PolarHBondContact O-N 2.7Å; L442-A446 VanDerWaalsContact O-CB 3.3Å; L442-A446 WeakPolarHBondContact O-CB 3.31Å; L442-A446 PolarHBondContact O-N 2.96Å
443	S	94.4	Very high	92.6	Very high	18 Å²	18	34.2 Å²	34.2	13%	0.126	18%	0.181	C	C	.	.	H	α-helix	trans	-65.6	-49	179.6	-58.5	0	0	0	0	111.6	A439 L440 G441 G445 A446 S447	A439-S443 WeakPolarHBondContact O-CB 3.4Å; A439-S443 PolarHBondContact O-N 2.91Å; A439-S443 PolarHBondContact O-OG 3.01Å; L440-S443 WeakPolarHBondContact O-CB 3.44Å; L440-S443 PolarHBondContact O-N 2.98Å; G441-S443 VanDerWaalsContact C-N 3.33Å; G441-S443 PolarHBondContact O-N 2.8Å; S443-G445 PolarHBondContact O-N 3.17Å; S443-A446 PolarHBondContact O-N 3.2Å; S443-S447 PolarHBondContact O-N 3.16Å; S443-S447 PolarHBondContact O-OG 2.9Å
444	C	95.8	Very high	92.4	Very high	49 Å²	49	36.7 Å²	36.7	33%	0.331	20%	0.203	S	C	.	.	H	α-helix	trans	-60	-44.6	177.1	-69.8	0	0	0	0	111.8	T302 L440 S447 L448	T302-C444 HydrophobicContact CG2-CB 4.06Å; T302-C444 WeakPolarHBondContact OG1-CB 3.44Å; L440-C444 PolarHBondContact O-N 2.74Å; L440-C444 PolarHBondContact O-SG 3.42Å; L440-C444 VanDerWaalsContact O-SG 3.34Å; C444-S447 PolarHBondContact O-N 3.29Å; C444-L448 WeakPolarHBondContact O-CG 3.45Å; C444-L448 PolarHBondContact O-N 2.99Å
445	G	95.2	Very high	91.9	Very high	0 Å²	0	40.1 Å²	40.1	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-62.6	-46.3	176.5	0	0	0	0	0	112.3	T302 L305 S306 G441 S443 S447 L448 S449	T302-G445 WeakPolarHBondContact O-CA 3.48Å; L305-G445 CarbonylContact C-O 3.57Å; S306-G445 VanDerWaalsContact CA-O 3.25Å; S306-G445 WeakPolarHBondContact CA-O 3.39Å; S306-G445 PolarHBondContact N-O 3.04Å; G441-G445 PolarHBondContact O-N 3.29Å; S443-G445 PolarHBondContact O-N 3.17Å; G445-S447 VanDerWaalsContact C-N 3.34Å; G445-S447 PolarHBondContact O-N 3.27Å; G445-L448 PolarHBondContact O-N 2.8Å; G445-S449 PolarHBondContact O-N 2.89Å
446	A	91.8	Very high	91.2	Very high	7 Å²	7	41 Å²	41	6%	0.058	23%	0.226	C	C	.	.	H	α-helix	trans	-58.6	-44.1	176.2	0	0	0	0	0	111.8	T72 Q76 L442 S443 S449 F450	T72-A446 HydrophobicContact CG2-CB 3.86Å; Q76-A446 HydrophobicContact CG-CB 4.18Å; L442-A446 VanDerWaalsContact O-CB 3.3Å; L442-A446 WeakPolarHBondContact O-CB 3.31Å; L442-A446 PolarHBondContact O-N 2.96Å; S443-A446 PolarHBondContact O-N 3.2Å; A446-S449 WeakPolarHBondContact O-CB 3.46Å; A446-S449 PolarHBondContact O-N 3.25Å; A446-S449 PolarHBondContact O-OG 3.24Å; A446-F450 WeakPolarHBondContact O-CD2 3.3Å
447	S	91.6	Very high	91.1	Very high	83 Å²	83	41.4 Å²	41.4	58%	0.58	23%	0.23	S	C	*	.	H	α-helix	trans	-61.1	-44.9	175.2	-61.8	0	0	0	0	112.8	S443 C444 G445 S449 F450	S443-S447 PolarHBondContact O-N 3.16Å; S443-S447 PolarHBondContact O-OG 2.9Å; C444-S447 PolarHBondContact O-N 3.29Å; G445-S447 VanDerWaalsContact C-N 3.34Å; G445-S447 PolarHBondContact O-N 3.27Å; S447-S449 VanDerWaalsContact C-N 3.28Å; S447-S449 PolarHBondContact O-N 3.03Å; S447-F450 PolarHBondContact O-N 3.27Å
448	L	93.6	Very high	90.9	Very high	60 Å²	60	42.2 Å²	42.2	31%	0.314	24%	0.236	S	C	.	.	H	α-helix	trans	-65.8	-30.9	177	-73.3	176.1	0	0	0	112.7	T302 C444 G445 F450 L451 F452	T302-L448 HydrophobicContact CG2-CD1 3.53Å; C444-L448 WeakPolarHBondContact O-CG 3.45Å; C444-L448 PolarHBondContact O-N 2.99Å; G445-L448 PolarHBondContact O-N 2.8Å; L448-F450 VanDerWaalsContact C-N 3.25Å; L448-F450 PolarHBondContact O-N 2.87Å; L448-L451 HydrophobicContact CD2-CD2 4.41Å; L448-L451 WeakPolarHBondContact O-CB 3.46Å; L448-L451 PolarHBondContact O-N 3.37Å; L448-F452 HydrophobicContact CB-CE2 4.32Å; L448-F452 PolarHBondContact O-N 2.97Å
449	S	91.3	Very high	90.7	Very high	12 Å²	12	43.9 Å²	43.9	8%	0.084	25%	0.246	C	C	.	.	H	α-helix	trans	-60.3	-35.9	178.1	82.2	0	0	0	0	112.5	L305 S306 G445 A446 S447 F452 K453	L305-S449 WeakPolarHBondContact O-CB 3.3Å; S306-S449 WeakPolarHBondContact O-CA 3.49Å; S306-S449 WeakPolarHBondContact O-CB 3.36Å; G445-S449 PolarHBondContact O-N 2.89Å; A446-S449 WeakPolarHBondContact O-CB 3.46Å; A446-S449 PolarHBondContact O-N 3.25Å; A446-S449 PolarHBondContact O-OG 3.24Å; S447-S449 VanDerWaalsContact C-N 3.28Å; S447-S449 PolarHBondContact O-N 3.03Å; S449-F452 PolarHBondContact O-N 2.96Å; S449-K453 VanDerWaalsContact O-CB 3.23Å; S449-K453 WeakPolarHBondContact O-CB 3.43Å; S449-K453 PolarHBondContact O-N 3.44Å
450	F	88.1	Confident	90.5	Very high	86 Å²	86	46.5 Å²	46.5	38%	0.377	26%	0.26	S	S	.	.	H	α-helix	trans	-64.5	-41.1	174.2	-69.7	-74.6	0	0	0	111.8	N69 T72 A446 S447 L448 K453 A454	N69-F450 HydrophobicContact CB-CE1 4.46Å; N69-F450 WeakPolarHBondContact OD1-CE1 3.24Å; T72-F450 HydrophobicContact CG2-CE2 4.04Å; T72-F450 HydrophobicContact CG2-CZ 4.18Å; A446-F450 WeakPolarHBondContact O-CD2 3.3Å; S447-F450 PolarHBondContact O-N 3.27Å; L448-F450 VanDerWaalsContact C-N 3.25Å; L448-F450 PolarHBondContact O-N 2.87Å; F450-K453 PolarHBondContact O-N 2.66Å; F450-A454 WeakPolarHBondContact O-CB 3.45Å; F450-A454 PolarHBondContact O-N 3.3Å
451	L	89.5	Confident	90.2	Very high	97 Å²	97	46.2 Å²	46.2	51%	0.508	26%	0.259	S	S	.	.	H	α-helix	trans	-64.6	-48.1	176.6	178.2	63.8	0	0	0	111.1	L448 K453 A454 L455	L448-L451 HydrophobicContact CD2-CD2 4.41Å; L448-L451 WeakPolarHBondContact O-CB 3.46Å; L448-L451 PolarHBondContact O-N 3.37Å; L451-K453 VanDerWaalsContact C-N 3.32Å; L451-K453 PolarHBondContact O-N 3.39Å; L451-A454 WeakPolarHBondContact O-CB 3.27Å; L451-A454 PolarHBondContact O-N 3.19Å; L451-A454 VanDerWaalsContact O-N 3.12Å; L451-L455 HydrophobicContact CG-CD1 4.24Å; L451-L455 WeakPolarHBondContact O-CG 3.18Å; L451-L455 PolarHBondContact O-N 3.21Å; L451-L455 VanDerWaalsContact O-N 3.09Å
452	F	89.3	Confident	89.7	Confident	36 Å²	36	49.3 Å²	49.3	16%	0.158	28%	0.277	C	S	.	.	H	α-helix	trans	-64.9	-36.7	178.8	-65.4	-27.7	0	0	0	112.4	I311 V372 M376 L448 S449 A454 L455 L456	I311-F452 HydrophobicContact CD1-CB 3.82Å; I311-F452 HydrophobicContact CG1-CB 4.27Å; V372-F452 HydrophobicContact CG1-CD2 4.02Å; V372-F452 HydrophobicContact CG1-CE1 4.33Å; V372-F452 HydrophobicContact CG1-CE2 3.48Å; V372-F452 VanDerWaalsContact CG1-CE2 3.48Å; V372-F452 HydrophobicContact CG1-CZ 3.68Å; V372-F452 HydrophobicContact CG2-CE2 4.46Å; M376-F452 HydrophobicContact CE-CB 4.12Å; M376-F452 HydrophobicContact CE-CD1 4.4Å; M376-F452 HydrophobicContact CE-CG 4.49Å; M376-F452 HydrophobicContact SD-CB 4.26Å; M376-F452 HydrophobicContact SD-CD1 4.13Å; M376-F452 HydrophobicContact SD-CG 4.15Å; L448-F452 HydrophobicContact CB-CE2 4.32Å; L448-F452 PolarHBondContact O-N 2.97Å; S449-F452 PolarHBondContact O-N 2.96Å; F452-A454 VanDerWaalsContact C-N 3.29Å; F452-A454 PolarHBondContact O-N 3.4Å; F452-L455 HydrophobicContact CD1-CD1 4.18Å; F452-L455 PolarHBondContact O-N 3.3Å; F452-L456 PolarHBondContact O-N 3.2Å; F452-L456 VanDerWaalsContact O-N 3.14Å
453	K	85.3	Confident	89.4	Confident	109 Å²	109	50.8 Å²	50.8	47%	0.474	29%	0.286	S	S	.	.	H	α-helix	trans	-63.7	-34.1	173.1	-171.7	176.8	-178.9	-178.1	0	112.4	I311 M314 S449 F450 L451 L455	I311-K453 HydrophobicContact CD1-CB 4.23Å; M314-K453 HydrophobicContact SD-CG 4.34Å; S449-K453 VanDerWaalsContact O-CB 3.23Å; S449-K453 WeakPolarHBondContact O-CB 3.43Å; S449-K453 PolarHBondContact O-N 3.44Å; F450-K453 PolarHBondContact O-N 2.66Å; L451-K453 VanDerWaalsContact C-N 3.32Å; L451-K453 PolarHBondContact O-N 3.39Å; K453-L455 VanDerWaalsContact C-N 3.33Å
454	A	85.1	Confident	89	Confident	62 Å²	62	53.3 Å²	53.3	51%	0.512	30%	0.298	S	S	.	.	H	α-helix	trans	-76	-19.9	175.7	0	0	0	0	0	113.8	F450 L451 F452	F450-A454 WeakPolarHBondContact O-CB 3.45Å; F450-A454 PolarHBondContact O-N 3.3Å; L451-A454 WeakPolarHBondContact O-CB 3.27Å; L451-A454 PolarHBondContact O-N 3.19Å; L451-A454 VanDerWaalsContact O-N 3.12Å; F452-A454 VanDerWaalsContact C-N 3.29Å; F452-A454 PolarHBondContact O-N 3.4Å
455	L	83.9	Confident	88.4	Confident	74 Å²	74	53.7 Å²	53.7	39%	0.387	30%	0.296	S	S	.	.	H	α-helix	trans	-86.3	-27.3	177.5	-73.2	170.7	0	0	0	113.3	M376 L451 F452 K453	M376-L455 HydrophobicContact CE-CB 4.11Å; L451-L455 HydrophobicContact CG-CD1 4.24Å; L451-L455 WeakPolarHBondContact O-CG 3.18Å; L451-L455 PolarHBondContact O-N 3.21Å; L451-L455 VanDerWaalsContact O-N 3.09Å; F452-L455 HydrophobicContact CD1-CD1 4.18Å; F452-L455 PolarHBondContact O-N 3.3Å; K453-L455 VanDerWaalsContact C-N 3.33Å
456	L	76.6	Confident	87.8	Confident	18 Å²	18	58.5 Å²	58.5	9%	0.094	32%	0.322	C	S	.	.			trans	-62.8	0	168.3	-86.2	159.6	0	0	0	110.7	I311 M376 V380 R383 S384 F452	I311-L456 HydrophobicContact CD1-CD1 3.62Å; I311-L456 HydrophobicContact CG2-CD1 3.98Å; M376-L456 HydrophobicContact CE-CG 4.37Å; V380-L456 HydrophobicContact CB-CD2 4.48Å; V380-L456 HydrophobicContact CG2-CD2 4.29Å; R383-L456 CarbonylContact C-O 3.59Å; R383-L456 WeakPolarHBondContact CA-O 3.4Å; R383-L456 WeakPolarHBondContact CB-O 3.39Å; S384-L456 PolarHBondContact N-O 3.19Å; S384-L456 PolarHBondContact OG-O 3.34Å; S384-L456 PolarHBondContact OG-OXT 3.02Å; F452-L456 PolarHBondContact O-N 3.2Å; F452-L456 VanDerWaalsContact O-N 3.14Å

Retrieved 456 of 456 residues in 186.2 ms (Link to these results)

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