A0A096NEA4_PAPAN Loading...

Diacylglycerol lipase-alpha

AlphaFold DB , UniProt , Accession A0A096NEA4, Species PAPAN (Papio anubis, Olive baboon), Gene DAGLA, Length 1,042 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M54.9Low74.7Confident27 Ų2753.4 Ų53.413%0.13324%0.241CC..  088.80-65.3136.1-174.200109.5G3 I85 L86 D230 I231 D235 L545M1-G3 PolarHBondContact O-N 3.18Å; M1-I85 HydrophobicContact CE-CB 3.67Å; M1-I85 HydrophobicContact CE-CG2 3.56Å; M1-I85 HydrophobicContact CG-CG2 3.91Å; M1-I85 WeakPolarHBondContact CG-O 3.46Å; M1-I85 HydrophobicContact SD-CB 4.48Å; M1-I85 HydrophobicContact SD-CG2 3.72Å; M1-L86 HydrophobicContact CE-CD2 3.89Å; M1-L86 HydrophobicContact CE-CG 3.67Å; M1-L86 HydrophobicContact CG-CD2 4.04Å; M1-D230 CarbonylContact C-O 3.59Å; M1-D230 VanDerWaalsContact CA-O 3.3Å; M1-D230 WeakPolarHBondContact CA-O 3.44Å; M1-D230 WeakPolarHBondContact CB-O 3.05Å; M1-D230 PolarHBondContact N-O 3.23Å; M1-D230 CarbonylContact O-C 3.59Å; M1-I231 HydrophobicContact SD-CG1 4.46Å; M1-D235 VanDerWaalsContact CB-OD2 3.27Å; M1-D235 WeakPolarHBondContact CB-OD2 3.27Å; M1-D235 HydrophobicContact SD-CB 3.75Å; M1-L545 HydrophobicContact CE-CB 3.89Å; M1-L545 HydrophobicContact CE-CD2 4.13Å; M1-L545 HydrophobicContact CE-CG 4.42Å
2P63.6Low74.2Confident47 Ų4751.4 Ų51.431%0.30524%0.238SC..PPolyproline II helixtrans-65.4118.5-178.928.3-33.3000110.4T88P2-T88 HydrophobicContact CG-CG2 4.36Å
3G69.8Low74.6Confident1 Ų149.6 Ų49.61%0.0123%0.233CC..PPolyproline II helixtrans-56.1142.4166.900000110.5M1 W11 V13M1-G3 PolarHBondContact O-N 3.18Å; G3-W11 CarbonylContact C-O 3.58Å; G3-W11 WeakPolarHBondContact CA-O 3.17Å; G3-V13 CarbonylContact C-O 3.5Å; G3-V13 WeakPolarHBondContact CA-O 3.48Å
4I81.1Confident75Confident25 Ų2546.4 Ų46.413%0.12822%0.22CC..PPolyproline II helixtrans-57.3139.7-163.8-163.9175.7000111.9V6 R10 W11 V13 M94 L98I4-V6 HydrophobicContact CD1-CG2 3.97Å; I4-V6 HydrophobicContact CG1-CG2 3.85Å; I4-V6 HydrophobicContact CG2-CG2 4.14Å; I4-R10 CarbonylContact O-C 3.55Å; I4-R10 WeakPolarHBondContact O-CA 3.41Å; I4-W11 HydrophobicContact CG2-CB 4.05Å; I4-W11 HydrophobicContact CG2-CG 4.48Å; I4-W11 PolarHBondContact O-N 2.93Å; I4-V13 WeakPolarHBondContact CG2-O 3.27Å; I4-V13 PolarHBondContact N-O 3.1Å; I4-M94 HydrophobicContact CD1-CB 4.35Å; I4-M94 HydrophobicContact CD1-CG 3.69Å; I4-L98 HydrophobicContact CD1-CD1 3.55Å
5V80.4Confident75.5Confident65 Ų6544.3 Ų44.339%0.39421%0.212SC..EExtended strand (participates in β ladder)trans-104.6107.9-179.9-178.60000109.5R9 R10 V165V5-R9 WeakPolarHBondContact CA-O 3.33Å; V5-R10 HydrophobicContact CG2-CB 4.49Å; V5-V165 HydrophobicContact CG1-CG2 3.99Å; V5-V165 HydrophobicContact CG2-CG2 4.35Å
6V79.8Confident76Confident9 Ų942.3 Ų42.36%0.05520%0.202CC..EExtended strand (participates in β ladder)trans-133.5141.3-178-1660000108.1I4 R8 R9 W11 L98 Y99I4-V6 HydrophobicContact CD1-CG2 3.97Å; I4-V6 HydrophobicContact CG1-CG2 3.85Å; I4-V6 HydrophobicContact CG2-CG2 4.14Å; V6-R8 PolarHBondContact O-N 3.47Å; V6-R9 PolarHBondContact N-O 3.29Å; V6-R9 PolarHBondContact O-N 3.12Å; V6-W11 PolarHBondContact O-NE1 3.25Å; V6-L98 HydrophobicContact CG2-CD1 4.28Å; V6-Y99 HydrophobicContact CG1-CD1 4.22Å; V6-Y99 HydrophobicContact CG1-CE1 3.4Å
7F80.6Confident76.4Confident102 Ų10241.8 Ų41.845%0.44720%0.201SC..THydrogen-bonded Turntrans54.335.5-172.7-54.2-73.5000114.5R9 W11 Y99 L102F7-R9 PolarHBondContact O-N 3.22Å; F7-W11 HydrophobicContact CD2-CZ2 4.43Å; F7-Y99 AromaticContact CD1-CE1 3.86Å; F7-Y99 HydrophobicContact CD1-CE1 3.86Å; F7-Y99 HydrophobicContact CD2-CE1 4.32Å; F7-Y99 AromaticContact CE1-CD1 3.85Å; F7-Y99 HydrophobicContact CE1-CD1 3.85Å; F7-Y99 AromaticContact CE1-CE1 3.49Å; F7-Y99 HydrophobicContact CE1-CE1 3.49Å; F7-Y99 VanDerWaalsContact CE1-CE1 3.49Å; F7-Y99 HydrophobicContact CE2-CD1 4.37Å; F7-Y99 AromaticContact CE2-CE1 3.99Å; F7-Y99 HydrophobicContact CE2-CE1 3.99Å; F7-Y99 HydrophobicContact CG-CE1 4.25Å; F7-Y99 AromaticContact CZ-CD1 3.68Å; F7-Y99 HydrophobicContact CZ-CD1 3.68Å; F7-Y99 AromaticContact CZ-CE1 3.55Å; F7-Y99 HydrophobicContact CZ-CE1 3.55Å; F7-Y99 PolarHBondContact N-OH 3.06Å; F7-Y99 VanDerWaalsContact N-OH 3.13Å; F7-L102 HydrophobicContact CE2-CD2 4.21Å; F7-L102 HydrophobicContact CZ-CD2 3.58Å
8R78.1Confident77Confident220 Ų22041.4 Ų41.483%0.8320%0.201SC*.THydrogen-bonded Turntrans56.328-175.1-56179178172.9-1113.6V6V6-R8 PolarHBondContact O-N 3.47Å
9R78.3Confident77.5Confident36 Ų3639.4 Ų39.414%0.13619%0.191CC..EExtended strand (participates in β ladder)trans-129.1134.5177.2165.8172.5-101.4136.4-2.6109.1V5 V6 F7 W11 F157 D158 P159 R162V5-R9 WeakPolarHBondContact CA-O 3.33Å; V6-R9 PolarHBondContact N-O 3.29Å; V6-R9 PolarHBondContact O-N 3.12Å; F7-R9 PolarHBondContact O-N 3.22Å; R9-W11 VanDerWaalsContact O-CD1 3.24Å; R9-F157 VanDerWaalsContact CZ-CZ 3.44Å; R9-D158 WeakPolarHBondContact CD-O 3.34Å; R9-D158 PolarHBondContact NE-O 3.19Å; R9-P159 PolarHBondContact NH2-O 2.87Å; R9-R162 HydrophobicContact CB-CG 3.85Å; R9-R162 HydrophobicContact CG-CG 4.38Å
10R78.3Confident77.9Confident16 Ų1642.7 Ų42.76%0.0621%0.209CC..EExtended strand (participates in β ladder)trans-68.2142.1163.7171.2178176.81773.2110.1I4 V5 G161 F164 D230I4-R10 CarbonylContact O-C 3.55Å; I4-R10 WeakPolarHBondContact O-CA 3.41Å; V5-R10 HydrophobicContact CG2-CB 4.49Å; R10-G161 PolarHBondContact N-O 3.01Å; R10-G161 WeakPolarHBondContact O-CA 3.4Å; R10-F164 HydrophobicContact CB-CD1 4.11Å; R10-F164 VanDerWaalsContact CD-CD1 3.48Å; R10-F164 HydrophobicContact CG-CD1 4.42Å; R10-D230 IonicContact CZ-OD1 3.41Å; R10-D230 IonicContact NH1-OD1 2.67Å; R10-D230 PolarHBondContact NH1-OD1 3.19Å; R10-D230 IonicContact NH2-OD1 3.48Å; R10-D230 PolarHBondContact NH2-OD1 3.36Å
11W76.7Confident78.3Confident39 Ų3944 Ų4415%0.14822%0.221CC..  trans-113.8163.4170.4-61.872.6000109.8G3 I4 V6 F7 R9 V13 V153 V156 F157G3-W11 CarbonylContact C-O 3.58Å; G3-W11 WeakPolarHBondContact CA-O 3.17Å; I4-W11 HydrophobicContact CG2-CB 4.05Å; I4-W11 HydrophobicContact CG2-CG 4.48Å; I4-W11 PolarHBondContact O-N 2.93Å; V6-W11 PolarHBondContact O-NE1 3.25Å; F7-W11 HydrophobicContact CD2-CZ2 4.43Å; R9-W11 VanDerWaalsContact O-CD1 3.24Å; W11-V13 VanDerWaalsContact C-N 3.27Å; W11-V13 PolarHBondContact O-N 3.04Å; W11-V153 HydrophobicContact CH2-CG1 4.23Å; W11-V153 HydrophobicContact CZ3-CG1 4.1Å; W11-V156 HydrophobicContact CB-CG1 4.37Å; W11-V156 HydrophobicContact CE3-CG1 4.2Å; W11-F157 HydrophobicContact CE3-CB 4.23Å; W11-F157 AromaticContact CH2-CD2 3.79Å; W11-F157 HydrophobicContact CH2-CD2 3.79Å; W11-F157 HydrophobicContact CZ2-CD2 4.4Å; W11-F157 HydrophobicContact CZ3-CB 3.82Å; W11-F157 AromaticContact CZ3-CD2 3.86Å; W11-F157 HydrophobicContact CZ3-CD2 3.86Å; W11-F157 HydrophobicContact CZ3-CG 4.3Å
12S69.4Low79.9Confident30 Ų3043 Ų4321%0.2122%0.217CC..SBendtrans-93.641.8179.868.40000113.2V156 R197S12-V156 PolarHBondContact N-O 2.96Å; S12-V156 PolarHBondContact OG-O 3.34Å; S12-V156 VanDerWaalsContact OG-O 3.11Å; S12-R197 PolarHBondContact OG-NH1 3.35Å; S12-R197 PolarHBondContact OG-NH2 2.95Å
13V78.8Confident81.2Confident28 Ų2843.9 Ų43.917%0.1722%0.218CC..SBendtrans-142.2139.4178.6143.20000107.4G3 I4 W11 D17 L18 V156G3-V13 CarbonylContact C-O 3.5Å; G3-V13 WeakPolarHBondContact CA-O 3.48Å; I4-V13 WeakPolarHBondContact CG2-O 3.27Å; I4-V13 PolarHBondContact N-O 3.1Å; W11-V13 VanDerWaalsContact C-N 3.27Å; W11-V13 PolarHBondContact O-N 3.04Å; V13-D17 HydrophobicContact CG1-CB 4.23Å; V13-L18 HydrophobicContact CG1-CD2 4.18Å; V13-V156 HydrophobicContact CB-CG1 3.58Å; V13-V156 HydrophobicContact CG2-CB 4.29Å; V13-V156 HydrophobicContact CG2-CG1 3.46Å; V13-V156 VanDerWaalsContact CG2-CG1 3.46Å; V13-V156 HydrophobicContact CG2-CG2 3.74Å
14G80.4Confident82.2Confident5 Ų550.1 Ų50.15%0.05225%0.245CC..  trans-82.2158.5171.800000111.7D16 D17G14-D16 WeakPolarHBondContact CA-OD1 3.26Å; G14-D16 PolarHBondContact O-N 2.96Å; G14-D17 WeakPolarHBondContact CA-OD2 2.95Å; G14-D17 PolarHBondContact N-OD2 2.96Å; G14-D17 PolarHBondContact O-N 3.14Å
15S82.8Confident82.6Confident14 Ų1450.4 Ų50.410%0.09825%0.247CC..THydrogen-bonded Turntrans-66.5-11.8174.750.20000113.6S80 R91S15-S80 VanDerWaalsContact O-CB 3.24Å; S15-S80 WeakPolarHBondContact O-CB 3.5Å; S15-S80 PolarHBondContact O-OG 2.84Å; S15-R91 WeakPolarHBondContact OG-CD 3.48Å; S15-R91 PolarHBondContact OG-NH1 3.18Å; S15-R91 VanDerWaalsContact OG-NH1 3.14Å
16D82.8Confident83.3Confident12 Ų1249.5 Ų49.56%0.06424%0.238CC..THydrogen-bonded Turntrans-94.8-17.617742.111.7000114.1G14 L18 V19 R91 K552G14-D16 WeakPolarHBondContact CA-OD1 3.26Å; G14-D16 PolarHBondContact O-N 2.96Å; D16-L18 PolarHBondContact O-N 3.01Å; D16-V19 WeakPolarHBondContact O-CG2 3.47Å; D16-R91 IonicContact OD1-NH1 2.86Å; D16-R91 IonicContact OD2-CZ 3.94Å; D16-R91 IonicContact OD2-NH1 2.81Å; D16-R91 PolarHBondContact OD2-NH1 3.37Å; D16-R91 IonicContact OD2-NH2 2.73Å; D16-K552 WeakPolarHBondContact OD1-CE 3.17Å; D16-K552 IonicContact OD1-NZ 3.03Å; D16-K552 PolarHBondContact OD1-NZ 3.05Å; D16-K552 WeakPolarHBondContact OD2-CE 3.26Å; D16-K552 IonicContact OD2-NZ 3.56Å
17D83.4Confident84Confident34 Ų3453.9 Ų53.918%0.18226%0.26CS..THydrogen-bonded Turntrans-71.5-20.3175.7-61.7-45.8000112.5V13 G14 V19 P21 S234 K552V13-D17 HydrophobicContact CG1-CB 4.23Å; G14-D17 WeakPolarHBondContact CA-OD2 2.95Å; G14-D17 PolarHBondContact N-OD2 2.96Å; G14-D17 PolarHBondContact O-N 3.14Å; D17-V19 PolarHBondContact O-N 3.17Å; D17-P21 VanDerWaalsContact O-CD 3.25Å; D17-P21 WeakPolarHBondContact O-CD 3.47Å; D17-S234 WeakPolarHBondContact OD1-CB 3.45Å; D17-S234 PolarHBondContact OD1-OG 2.92Å; D17-S234 PolarHBondContact OD2-OG 3.06Å; D17-S234 VanDerWaalsContact OD2-OG 3.12Å; D17-K552 WeakPolarHBondContact OD1-CE 3.41Å; D17-K552 IonicContact OD1-NZ 3.95Å; D17-K552 PolarHBondContact OD1-NZ 3.02Å; D17-K552 IonicContact OD2-NZ 3.91Å; D17-K552 PolarHBondContact OD2-NZ 3.36Å
18L87Confident84.5Confident36 Ų3650.6 Ų50.619%0.18825%0.247CC..THydrogen-bonded Turntrans-70.4-9.6-177.1-57.5172.8000113.7V13 D16 A22 I76 M94 L98V13-L18 HydrophobicContact CG1-CD2 4.18Å; D16-L18 PolarHBondContact O-N 3.01Å; L18-A22 WeakPolarHBondContact O-CB 3.49Å; L18-A22 PolarHBondContact O-N 2.94Å; L18-A22 VanDerWaalsContact O-N 3.07Å; L18-I76 HydrophobicContact CB-CG2 3.84Å; L18-I76 HydrophobicContact CD1-CG2 4.5Å; L18-M94 HydrophobicContact CD1-CE 4.49Å; L18-M94 HydrophobicContact CD1-CG 4.16Å; L18-M94 HydrophobicContact CD1-SD 3.83Å; L18-L98 HydrophobicContact CD1-CD1 4.12Å; L18-L98 HydrophobicContact CD1-CD2 4.13Å
19V86.9Confident85.2Confident3 Ų340.3 Ų40.32%0.01821%0.208CC..Hα-helixtrans-56.7-53.9177.8177.80000111.3D16 D17 A22 I23 S80 M81 W553D16-V19 WeakPolarHBondContact O-CG2 3.47Å; D17-V19 PolarHBondContact O-N 3.17Å; V19-A22 PolarHBondContact O-N 3.12Å; V19-I23 HydrophobicContact CG1-CD1 3.64Å; V19-I23 HydrophobicContact CG1-CG1 4.43Å; V19-I23 VanDerWaalsContact O-CG1 3.3Å; V19-I23 WeakPolarHBondContact O-CG1 3Å; V19-I23 PolarHBondContact O-N 3.09Å; V19-S80 VanDerWaalsContact CG2-CB 3.4Å; V19-M81 HydrophobicContact CG1-CG 4.26Å; V19-M81 HydrophobicContact CG2-CG 4.02Å; V19-W553 HydrophobicContact CG1-CB 4.35Å; V19-W553 HydrophobicContact CG1-CG 4.46Å; V19-W553 HydrophobicContact CG2-CB 4.49Å
20L84.4Confident86Confident104 Ų10440.5 Ų40.555%0.54521%0.214SC..Hα-helixtrans-69.6-45.6-172.7-60.8175.9000112.8A22 I23 F24L20-A22 VanDerWaalsContact C-N 3.33Å; L20-A22 PolarHBondContact O-N 2.65Å; L20-I23 PolarHBondContact O-N 3.32Å; L20-F24 PolarHBondContact O-N 3.39Å
21P86.9Confident86.7Confident71 Ų7143.6 Ų43.646%0.46123%0.234SC..Hα-helixtrans-60.5-39.6173.2-24.635.4000113.1D17 F24 L25D17-P21 VanDerWaalsContact O-CD 3.25Å; D17-P21 WeakPolarHBondContact O-CD 3.47Å; P21-F24 PolarHBondContact O-N 3.15Å; P21-L25 WeakPolarHBondContact O-CB 3.26Å; P21-L25 WeakPolarHBondContact O-CG 3.35Å; P21-L25 PolarHBondContact O-N 3.07Å
22A89.6Confident87.5Confident6 Ų644 Ų445%0.0524%0.236CC..Hα-helixtrans-70.3-36.9179.800000112.5L18 V19 L20 F26 I76 I77L18-A22 WeakPolarHBondContact O-CB 3.49Å; L18-A22 PolarHBondContact O-N 2.94Å; L18-A22 VanDerWaalsContact O-N 3.07Å; V19-A22 PolarHBondContact O-N 3.12Å; L20-A22 VanDerWaalsContact C-N 3.33Å; L20-A22 PolarHBondContact O-N 2.65Å; A22-F26 WeakPolarHBondContact O-CB 3.32Å; A22-F26 PolarHBondContact O-N 2.96Å; A22-I76 HydrophobicContact CB-CB 4.21Å; A22-I76 HydrophobicContact CB-CG2 3.78Å; A22-I77 HydrophobicContact CB-CD1 4.26Å; A22-I77 HydrophobicContact CB-CG1 3.61Å
23I89.8Confident88.6Confident65 Ų6545.3 Ų45.333%0.33324%0.238SC..Hα-helixtrans-62.8-45.2172.1-70.6170.3000110.8V19 L20 F26 L27 I77V19-I23 HydrophobicContact CG1-CD1 3.64Å; V19-I23 HydrophobicContact CG1-CG1 4.43Å; V19-I23 VanDerWaalsContact O-CG1 3.3Å; V19-I23 WeakPolarHBondContact O-CG1 3Å; V19-I23 PolarHBondContact O-N 3.09Å; L20-I23 PolarHBondContact O-N 3.32Å; I23-F26 PolarHBondContact O-N 3.37Å; I23-L27 HydrophobicContact CG2-CD1 3.91Å; I23-L27 HydrophobicContact CG2-CG 4.49Å; I23-L27 WeakPolarHBondContact O-CG 3.31Å; I23-L27 PolarHBondContact O-N 3.15Å; I23-I77 HydrophobicContact CG1-CD1 3.81Å; I23-I77 HydrophobicContact CG1-CG1 3.98Å; I23-I77 HydrophobicContact CG1-CG2 4.35Å
24F90.1Very high89.3Confident133 Ų13347.8 Ų47.858%0.58325%0.253SS*.Hα-helixtrans-60.6-48.6178.3176-97.1000112L20 P21 L27 L28L20-F24 PolarHBondContact O-N 3.39Å; P21-F24 PolarHBondContact O-N 3.15Å; F24-L27 PolarHBondContact O-N 2.85Å; F24-L28 HydrophobicContact CE1-CD1 4.2Å; F24-L28 HydrophobicContact CZ-CD1 4.33Å; F24-L28 WeakPolarHBondContact O-CB 3.24Å; F24-L28 PolarHBondContact O-N 3.2Å
25L91.1Very high89.9Confident30 Ų3050.7 Ų50.716%0.15727%0.267CS..Hα-helixtrans-62.6-43.3176.5-70.3173.6000111.8P21 L27 L28 H29 E73 V145P21-L25 WeakPolarHBondContact O-CB 3.26Å; P21-L25 WeakPolarHBondContact O-CG 3.35Å; P21-L25 PolarHBondContact O-N 3.07Å; L25-L27 VanDerWaalsContact C-N 3.35Å; L25-L27 PolarHBondContact O-N 2.74Å; L25-L28 PolarHBondContact O-N 2.64Å; L25-H29 VanDerWaalsContact O-CG 3.32Å; L25-H29 PolarHBondContact O-N 2.78Å; L25-H29 PolarHBondContact O-ND1 3.09Å; L25-E73 HydrophobicContact CB-CG 4.45Å; L25-V145 HydrophobicContact CD2-CG1 3.79Å
26F94.1Very high90.2Very high47 Ų4750.2 Ų50.221%0.20626%0.263CS..Hα-helixtrans-59.6-43.1178.1177.9-95.8000112.3A22 I23 T30 M70 E73 M74 I77A22-F26 WeakPolarHBondContact O-CB 3.32Å; A22-F26 PolarHBondContact O-N 2.96Å; I23-F26 PolarHBondContact O-N 3.37Å; F26-T30 VanDerWaalsContact O-CB 3.27Å; F26-T30 WeakPolarHBondContact O-CB 3.39Å; F26-T30 PolarHBondContact O-N 3.38Å; F26-T30 PolarHBondContact O-OG1 3.4Å; F26-M70 HydrophobicContact CD2-CB 4.07Å; F26-M70 HydrophobicContact CD2-CG 4.11Å; F26-M70 HydrophobicContact CE2-CB 3.9Å; F26-M70 HydrophobicContact CE2-CE 3.83Å; F26-M70 HydrophobicContact CE2-CG 4.09Å; F26-M70 HydrophobicContact CZ-CE 4.05Å; F26-E73 HydrophobicContact CB-CB 4.27Å; F26-E73 PolarHBondContact N-OE2 2.96Å; F26-M74 HydrophobicContact CD1-SD 4.46Å; F26-M74 HydrophobicContact CD2-CG 3.74Å; F26-M74 HydrophobicContact CD2-SD 4.01Å; F26-M74 HydrophobicContact CE1-SD 4.2Å; F26-M74 HydrophobicContact CE2-CG 3.38Å; F26-M74 HydrophobicContact CE2-SD 3.72Å; F26-M74 HydrophobicContact CG-SD 4.38Å; F26-M74 HydrophobicContact CZ-CG 4.03Å; F26-M74 HydrophobicContact CZ-SD 3.83Å; F26-I77 HydrophobicContact CB-CD1 4.2Å
27L93.7Very high90.6Very high100 Ų10050.9 Ų50.952%0.52427%0.269SS..Hα-helixtrans-66.5-39.7176.6-68.9168000111.8I23 F24 L25 T31I23-L27 HydrophobicContact CG2-CD1 3.91Å; I23-L27 HydrophobicContact CG2-CG 4.49Å; I23-L27 WeakPolarHBondContact O-CG 3.31Å; I23-L27 PolarHBondContact O-N 3.15Å; F24-L27 PolarHBondContact O-N 2.85Å; L25-L27 VanDerWaalsContact C-N 3.35Å; L25-L27 PolarHBondContact O-N 2.74Å; L27-T31 WeakPolarHBondContact O-CB 3.39Å; L27-T31 PolarHBondContact O-N 3.19Å; L27-T31 PolarHBondContact O-OG1 2.82Å
28L92.1Very high91Very high34 Ų3454 Ų5418%0.17829%0.288CS..Hα-helixtrans-64-47.9175.8-176.3151000111.4F24 L25 T31 W32 V145F24-L28 HydrophobicContact CE1-CD1 4.2Å; F24-L28 HydrophobicContact CZ-CD1 4.33Å; F24-L28 WeakPolarHBondContact O-CB 3.24Å; F24-L28 PolarHBondContact O-N 3.2Å; L25-L28 PolarHBondContact O-N 2.64Å; L28-T31 PolarHBondContact O-N 3.49Å; L28-W32 VanDerWaalsContact O-CD1 3.31Å; L28-W32 PolarHBondContact O-N 3.2Å; L28-V145 HydrophobicContact CD1-CG2 4.02Å; L28-V145 HydrophobicContact CD2-CG2 4.02Å
29H93.3Very high91Very high3 Ų353 Ų531%0.01428%0.284CS..Hα-helixtrans-66.5-38.8177.1-63.1133.3000112.3L25 T31 W32 F33 L66 M70 E73 R101 E108L25-H29 VanDerWaalsContact O-CG 3.32Å; L25-H29 PolarHBondContact O-N 2.78Å; L25-H29 PolarHBondContact O-ND1 3.09Å; H29-T31 VanDerWaalsContact C-N 3.32Å; H29-T31 PolarHBondContact O-N 3.12Å; H29-W32 PolarHBondContact O-N 3.04Å; H29-F33 WeakPolarHBondContact O-CB 3.24Å; H29-F33 PolarHBondContact O-N 2.83Å; H29-L66 HydrophobicContact CB-CD2 4.13Å; H29-M70 HydrophobicContact CB-CG 3.85Å; H29-E73 IonicContact CE1-OE1 3.97Å; H29-E73 PolarHBondContact CE1-OE1 3.14Å; H29-E73 VanDerWaalsContact CE1-OE1 3.23Å; H29-E73 IonicContact CE1-OE2 3.96Å; H29-E73 IonicContact CG-OE2 3.42Å; H29-E73 IonicContact ND1-OE1 3.51Å; H29-E73 PolarHBondContact ND1-OE1 2.96Å; H29-E73 IonicContact ND1-OE2 2.83Å; H29-E73 PolarHBondContact ND1-OE2 3.42Å; H29-R101 PolarHBondContact CE1-NH2 3.44Å; H29-E108 IonicContact NE2-OE1 3.27Å
30T94.1Very high90.9Very high41 Ų4153.6 Ų53.625%0.25229%0.287SS..Hα-helixtrans-59.6-43.9173.5-58.40000111.1F26 F33 V34 M70F26-T30 VanDerWaalsContact O-CB 3.27Å; F26-T30 WeakPolarHBondContact O-CB 3.39Å; F26-T30 PolarHBondContact O-N 3.38Å; F26-T30 PolarHBondContact O-OG1 3.4Å; T30-F33 PolarHBondContact O-N 3.06Å; T30-V34 WeakPolarHBondContact O-CG2 3.22Å; T30-V34 PolarHBondContact O-N 3.08Å; T30-M70 HydrophobicContact CG2-CE 4.34Å; T30-M70 WeakPolarHBondContact OG1-CE 3.47Å
31T93.6Very high91Very high80 Ų8056.1 Ų56.149%0.49129%0.294SS..Hα-helixtrans-61.5-48.6178.2-56.40000111.1L27 L28 H29 V34 I35L27-T31 WeakPolarHBondContact O-CB 3.39Å; L27-T31 PolarHBondContact O-N 3.19Å; L27-T31 PolarHBondContact O-OG1 2.82Å; L28-T31 PolarHBondContact O-N 3.49Å; H29-T31 VanDerWaalsContact C-N 3.32Å; H29-T31 PolarHBondContact O-N 3.12Å; T31-V34 PolarHBondContact O-N 2.99Å; T31-I35 HydrophobicContact CG2-CD1 3.97Å; T31-I35 VanDerWaalsContact O-CG1 3.32Å; T31-I35 WeakPolarHBondContact O-CG1 3.38Å; T31-I35 PolarHBondContact O-N 3.41Å
32W92.4Very high90.7Very high49 Ų4955.5 Ų55.519%0.18630%0.301CS..Hα-helixtrans-67-35.1176.4-78.2109.3000113.5L28 H29 I35 L36 L66 V134 G137 M138 C141L28-W32 VanDerWaalsContact O-CD1 3.31Å; L28-W32 PolarHBondContact O-N 3.2Å; H29-W32 PolarHBondContact O-N 3.04Å; W32-I35 HydrophobicContact CE3-CD1 4.47Å; W32-I35 HydrophobicContact CE3-CG2 4.44Å; W32-I35 HydrophobicContact CZ3-CG2 4.46Å; W32-I35 PolarHBondContact O-N 3.24Å; W32-L36 WeakPolarHBondContact O-CB 3.37Å; W32-L36 PolarHBondContact O-N 3.46Å; W32-L66 HydrophobicContact CB-CD1 4.18Å; W32-V134 HydrophobicContact CZ3-CG1 4.41Å; W32-G137 VanDerWaalsContact CH2-C 3.49Å; W32-M138 HydrophobicContact CE3-CB 4.06Å; W32-M138 HydrophobicContact CE3-CG 4.3Å; W32-M138 HydrophobicContact CH2-CB 4.37Å; W32-M138 HydrophobicContact CZ3-CB 3.87Å; W32-C141 HydrophobicContact CZ2-CB 3.72Å; W32-C141 PolarHBondContact NE1-SG 2.71Å
33F94Very high90.3Very high56 Ų5658.6 Ų58.625%0.24632%0.316CS..Hα-helixtrans-62.5-43.2176.1-177.9-83.9000111.2H29 T30 S37 L63 L66 L67 M70H29-F33 WeakPolarHBondContact O-CB 3.24Å; H29-F33 PolarHBondContact O-N 2.83Å; T30-F33 PolarHBondContact O-N 3.06Å; F33-S37 VanDerWaalsContact O-CB 3.26Å; F33-S37 WeakPolarHBondContact O-CB 3.43Å; F33-S37 PolarHBondContact O-N 3.26Å; F33-S37 PolarHBondContact O-OG 2.8Å; F33-L63 HydrophobicContact CD1-CD1 4.48Å; F33-L63 HydrophobicContact CD2-CD1 3.43Å; F33-L63 VanDerWaalsContact CD2-CD1 3.43Å; F33-L63 HydrophobicContact CD2-CG 4.08Å; F33-L63 HydrophobicContact CE2-CD1 3.48Å; F33-L63 VanDerWaalsContact CE2-CD1 3.48Å; F33-L63 HydrophobicContact CE2-CG 3.69Å; F33-L63 HydrophobicContact CG-CD1 3.95Å; F33-L63 HydrophobicContact CZ-CD1 4.05Å; F33-L63 HydrophobicContact CZ-CG 4.3Å; F33-L66 HydrophobicContact CB-CB 4.49Å; F33-L66 HydrophobicContact CB-CD1 4.28Å; F33-L66 HydrophobicContact CD2-CB 4.09Å; F33-L67 HydrophobicContact CE2-CB 4.1Å; F33-M70 HydrophobicContact CB-SD 4.08Å; F33-M70 HydrophobicContact CD2-SD 4.39Å; F33-M70 HydrophobicContact CG-SD 4.24Å
34V93.6Very high89.8Confident81 Ų8162.3 Ų62.349%0.49134%0.341SS..Hα-helixtrans-65.6-49.4175.31720000111.1T30 T31 L36 S37 V38T30-V34 WeakPolarHBondContact O-CG2 3.22Å; T30-V34 PolarHBondContact O-N 3.08Å; T31-V34 PolarHBondContact O-N 2.99Å; V34-L36 PolarHBondContact O-N 3.27Å; V34-S37 PolarHBondContact O-N 3.04Å; V34-V38 HydrophobicContact CG1-CG2 4.48Å; V34-V38 WeakPolarHBondContact O-CG2 3.15Å; V34-V38 PolarHBondContact O-N 3.47Å
35I91.7Very high89.2Confident65 Ų6557.8 Ų57.833%0.33332%0.321SS..Hα-helixtrans-57.1-48.8178.4-69166.2000110.8T31 W32 S37 V38 V39 V134T31-I35 HydrophobicContact CG2-CD1 3.97Å; T31-I35 VanDerWaalsContact O-CG1 3.32Å; T31-I35 WeakPolarHBondContact O-CG1 3.38Å; T31-I35 PolarHBondContact O-N 3.41Å; W32-I35 HydrophobicContact CE3-CD1 4.47Å; W32-I35 HydrophobicContact CE3-CG2 4.44Å; W32-I35 HydrophobicContact CZ3-CG2 4.46Å; W32-I35 PolarHBondContact O-N 3.24Å; I35-S37 PolarHBondContact O-N 3.19Å; I35-V38 PolarHBondContact O-N 3.36Å; I35-V39 WeakPolarHBondContact O-CB 3.3Å; I35-V39 WeakPolarHBondContact O-CG2 3.39Å; I35-V39 PolarHBondContact O-N 2.91Å; I35-V134 HydrophobicContact CG2-CG1 3.93Å; I35-V134 HydrophobicContact CG2-CG2 4.43Å
36L90.3Very high88.5Confident4 Ų460.4 Ų60.42%0.02134%0.335CS..Hα-helixtrans-67-36.6-178.9-174.860.3000112.3W32 V34 V39 L40 Y62 L63 L66 M138W32-L36 WeakPolarHBondContact O-CB 3.37Å; W32-L36 PolarHBondContact O-N 3.46Å; V34-L36 PolarHBondContact O-N 3.27Å; L36-V39 PolarHBondContact O-N 2.83Å; L36-L40 HydrophobicContact CD1-CD1 3.87Å; L36-L40 HydrophobicContact CD1-CG 4.03Å; L36-L40 HydrophobicContact CD2-CD1 4.46Å; L36-L40 HydrophobicContact CG-CD1 3.75Å; L36-L40 HydrophobicContact CG-CG 4.32Å; L36-L40 WeakPolarHBondContact O-CB 3.34Å; L36-L40 VanDerWaalsContact O-CG 3.29Å; L36-L40 WeakPolarHBondContact O-CG 3.18Å; L36-L40 PolarHBondContact O-N 3.43Å; L36-Y62 HydrophobicContact CD2-CD1 3.87Å; L36-L63 HydrophobicContact CB-CD1 4.38Å; L36-L63 HydrophobicContact CD2-CB 4.19Å; L36-L63 HydrophobicContact CD2-CD1 4.18Å; L36-L63 HydrophobicContact CG-CD1 4.32Å; L36-L66 HydrophobicContact CD2-CD1 4.14Å; L36-M138 HydrophobicContact CD1-SD 4.32Å; L36-M138 HydrophobicContact CD2-SD 4.08Å
37S90.8Very high87.4Confident26 Ų2662.8 Ų62.818%0.18236%0.355CS..Hα-helixtrans-64.7-46.2174.2-61.80000111.9F33 V34 I35 V39 L40 F41 L63F33-S37 VanDerWaalsContact O-CB 3.26Å; F33-S37 WeakPolarHBondContact O-CB 3.43Å; F33-S37 PolarHBondContact O-N 3.26Å; F33-S37 PolarHBondContact O-OG 2.8Å; V34-S37 PolarHBondContact O-N 3.04Å; I35-S37 PolarHBondContact O-N 3.19Å; S37-V39 VanDerWaalsContact C-N 3.27Å; S37-V39 PolarHBondContact O-N 2.91Å; S37-L40 PolarHBondContact O-N 3.2Å; S37-F41 WeakPolarHBondContact O-CB 3.35Å; S37-F41 WeakPolarHBondContact O-CD2 3.39Å; S37-F41 PolarHBondContact O-N 3.36Å; S37-L63 WeakPolarHBondContact OG-CD1 3.37Å
38V90.7Very high86.3Confident99 Ų9966.7 Ų66.760%0.637%0.37SS*.Hα-helixtrans-62-37.6177.4171.10000111.2V34 I35 G42V34-V38 HydrophobicContact CG1-CG2 4.48Å; V34-V38 WeakPolarHBondContact O-CG2 3.15Å; V34-V38 PolarHBondContact O-N 3.47Å; I35-V38 PolarHBondContact O-N 3.36Å; V38-G42 WeakPolarHBondContact O-CA 3.28Å; V38-G42 PolarHBondContact O-N 2.97Å
39V87.5Confident85.6Confident15 Ų1567.7 Ų67.79%0.09137%0.374CS..Hα-helixtrans-67.6-53.8175.3166.20000111.4I35 L36 S37 F41 L43 Y45 A131 V134I35-V39 WeakPolarHBondContact O-CB 3.3Å; I35-V39 WeakPolarHBondContact O-CG2 3.39Å; I35-V39 PolarHBondContact O-N 2.91Å; L36-V39 PolarHBondContact O-N 2.83Å; S37-V39 VanDerWaalsContact C-N 3.27Å; S37-V39 PolarHBondContact O-N 2.91Å; V39-F41 PolarHBondContact O-N 3.03Å; V39-L43 HydrophobicContact CG1-CD1 4.13Å; V39-L43 WeakPolarHBondContact O-CB 3.07Å; V39-L43 WeakPolarHBondContact O-CG 3.43Å; V39-L43 PolarHBondContact O-N 2.82Å; V39-Y45 WeakPolarHBondContact CG1-OH 3.1Å; V39-Y45 PolarHBondContact O-OH 2.89Å; V39-Y45 VanDerWaalsContact O-OH 3.09Å; V39-A131 HydrophobicContact CG1-CB 4.35Å; V39-V134 HydrophobicContact CG2-CG1 4.3Å; V39-V134 HydrophobicContact CG2-CG2 4.1Å
40L85.6Confident84.9Confident17 Ų1770.7 Ų70.79%0.08940%0.399CS..Hα-helixtrans-68.6-28.3-174.5-72.1171.4000115.1L36 S37 V56 G59L36-L40 HydrophobicContact CD1-CD1 3.87Å; L36-L40 HydrophobicContact CD1-CG 4.03Å; L36-L40 HydrophobicContact CD2-CD1 4.46Å; L36-L40 HydrophobicContact CG-CD1 3.75Å; L36-L40 HydrophobicContact CG-CG 4.32Å; L36-L40 WeakPolarHBondContact O-CB 3.34Å; L36-L40 VanDerWaalsContact O-CG 3.29Å; L36-L40 WeakPolarHBondContact O-CG 3.18Å; L36-L40 PolarHBondContact O-N 3.43Å; S37-L40 PolarHBondContact O-N 3.2Å; L40-V56 HydrophobicContact CD2-CB 4.48Å; L40-V56 HydrophobicContact CD2-CG1 4.38Å; L40-V56 HydrophobicContact CD2-CG2 4.48Å; L40-G59 VanDerWaalsContact CD1-C 3.46Å
41F85.8Confident84.1Confident157 Ų15769.3 Ų69.369%0.68939%0.391SS*.Hα-helixtrans-110.1-15.1-178.3-61.8-69.6000113.9S37 V39 L63S37-F41 WeakPolarHBondContact O-CB 3.35Å; S37-F41 WeakPolarHBondContact O-CD2 3.39Å; S37-F41 PolarHBondContact O-N 3.36Å; V39-F41 PolarHBondContact O-N 3.03Å; F41-L63 HydrophobicContact CE2-CD2 4.21Å
42G81Confident83.4Confident58 Ų5865.6 Ų65.660%0.59837%0.368SS*.Hα-helixtrans-100.1-15.3179.700000115.1V38V38-G42 WeakPolarHBondContact O-CA 3.28Å; V38-G42 PolarHBondContact O-N 2.97Å
43L81.7Confident82.9Confident71 Ų7167.2 Ų67.237%0.37238%0.38SS..SBendtrans-98.9146.5174.1-59.4-177.9000111.6V39 Y45 T130V39-L43 HydrophobicContact CG1-CD1 4.13Å; V39-L43 WeakPolarHBondContact O-CB 3.07Å; V39-L43 WeakPolarHBondContact O-CG 3.43Å; V39-L43 PolarHBondContact O-N 2.82Å; L43-Y45 HydrophobicContact CB-CD2 4.47Å; L43-Y45 HydrophobicContact CB-CE2 3.9Å; L43-Y45 WeakPolarHBondContact O-CD2 3.36Å; L43-T130 HydrophobicContact CD1-CG2 4.34Å
44V77.7Confident82.3Confident142 Ų14268 Ų6886%0.86139%0.387SS*.  trans-91.6115.5172.8-178.80000108.5
45Y78.7Confident81.8Confident39 Ų3964.4 Ų64.415%0.15337%0.365CS..  trans-99.6144.9-178.5-65.2-83.5000111.7V39 L43 P47 S52 V56 A131V39-Y45 WeakPolarHBondContact CG1-OH 3.1Å; V39-Y45 PolarHBondContact O-OH 2.89Å; V39-Y45 VanDerWaalsContact O-OH 3.09Å; L43-Y45 HydrophobicContact CB-CD2 4.47Å; L43-Y45 HydrophobicContact CB-CE2 3.9Å; L43-Y45 WeakPolarHBondContact O-CD2 3.36Å; Y45-P47 VanDerWaalsContact O-CD 3.27Å; Y45-P47 WeakPolarHBondContact O-CD 3.17Å; Y45-S52 WeakPolarHBondContact CD1-OG 3.46Å; Y45-V56 HydrophobicContact CD1-CG2 3.6Å; Y45-V56 HydrophobicContact CD2-CG2 3.61Å; Y45-V56 HydrophobicContact CE1-CG2 3.81Å; Y45-V56 HydrophobicContact CE2-CG2 3.84Å; Y45-V56 HydrophobicContact CG-CG2 3.46Å; Y45-V56 VanDerWaalsContact CG-CG2 3.46Å; Y45-A131 HydrophobicContact CE1-CB 4.13Å
46N75.3Confident81.4Confident85 Ų8561.8 Ų61.846%0.45535%0.352SS..  trans-80.2109.7179.8-82.8-23.4000111.2H48 E49N46-H48 PolarHBondContact O-N 2.82Å; N46-H48 VanDerWaalsContact O-N 3.1Å; N46-E49 HydrophobicContact CB-CB 4.35Å; N46-E49 HydrophobicContact CB-CG 4.25Å; N46-E49 PolarHBondContact ND2-OE1 2.93Å; N46-E49 VanDerWaalsContact ND2-OE1 3.09Å; N46-E49 PolarHBondContact O-N 2.79Å
47P71.6Confident81.1Confident97 Ų9765 Ų6563%0.6337%0.369SS*.THydrogen-bonded Turntrans-70.7-9.3-176.631.3-37.3000113.8Y45Y45-P47 VanDerWaalsContact O-CD 3.27Å; Y45-P47 WeakPolarHBondContact O-CD 3.17Å
48H70.6Confident80.9Confident182 Ų18264.4 Ų64.484%0.84336%0.363SS*.THydrogen-bonded Turntrans-91.3-11.4177.6-59.7-57.7000113.4N46N46-H48 PolarHBondContact O-N 2.82Å; N46-H48 VanDerWaalsContact O-N 3.1Å
49E77.9Confident80.8Confident55 Ų5559.9 Ų59.926%0.25734%0.337SS..  trans-96.7113.2177-73.8-176.3-136.500110.8N46 C51 S52 L53N46-E49 HydrophobicContact CB-CB 4.35Å; N46-E49 HydrophobicContact CB-CG 4.25Å; N46-E49 PolarHBondContact ND2-OE1 2.93Å; N46-E49 VanDerWaalsContact ND2-OE1 3.09Å; N46-E49 PolarHBondContact O-N 2.79Å; E49-C51 PolarHBondContact O-N 3.21Å; E49-C51 VanDerWaalsContact O-N 3.1Å; E49-S52 PolarHBondContact O-N 3.34Å; E49-L53 PolarHBondContact O-N 2.87Å
50A77.4Confident80.9Confident66 Ų6665.5 Ų65.555%0.54536%0.356SS..Hα-helixtrans-57.8-25.5175.800000113N54A50-N54 VanDerWaalsContact O-CB 3.31Å; A50-N54 WeakPolarHBondContact O-CB 3.35Å; A50-N54 VanDerWaalsContact O-CG 3.27Å; A50-N54 PolarHBondContact O-N 2.96Å; A50-N54 VanDerWaalsContact O-N 3.13Å; A50-N54 PolarHBondContact O-ND2 3.24Å
51C78.8Confident81.1Confident12 Ų1266.1 Ų66.18%0.08137%0.366CS..Hα-helixtrans-63.8-52172.4-170.80000111.9E49 L55 Y122 C126E49-C51 PolarHBondContact O-N 3.21Å; E49-C51 VanDerWaalsContact O-N 3.1Å; C51-L55 WeakPolarHBondContact O-CB 3.26Å; C51-L55 PolarHBondContact O-N 3.47Å; C51-Y122 HydrophobicContact CB-CD1 4.28Å; C51-C126 HydrophobicContact CB-CB 4.35Å; C51-C126 WeakPolarHBondContact CB-SG 3.44Å; C51-C126 WeakPolarHBondContact SG-CB 3.43Å; C51-C126 CovalentContact SG-SG 2.03Å; C51-C126 PolarHBondContact SG-SG 2.89Å
52S78.8Confident81.3Confident1 Ų159.1 Ų59.11%0.00734%0.336CS..Hα-helixtrans-67.6-40-177.5-155.10000111.2Y45 E49 L55 V56 D128Y45-S52 WeakPolarHBondContact CD1-OG 3.46Å; E49-S52 PolarHBondContact O-N 3.34Å; S52-L55 WeakPolarHBondContact O-CB 3.48Å; S52-L55 PolarHBondContact O-N 2.98Å; S52-V56 WeakPolarHBondContact O-CG2 3.4Å; S52-V56 PolarHBondContact O-N 3Å; S52-D128 WeakPolarHBondContact CB-OD2 3.34Å; S52-D128 PolarHBondContact OG-OD2 3.05Å
53L81.3Confident81.8Confident84 Ų8457.6 Ų57.644%0.4431%0.314SS..Hα-helixtrans-61.8-51.7174.5-175.764.4000112.5E49 L55 V56 D57E49-L53 PolarHBondContact O-N 2.87Å; L53-L55 PolarHBondContact O-N 3.3Å; L53-V56 PolarHBondContact O-N 3.1Å; L53-D57 PolarHBondContact O-N 2.96Å
54N82.3Confident82.4Confident73 Ų7356 Ų5639%0.3931%0.314SS..Hα-helixtrans-60.8-34.2177.6-77.5-38.8000112.2A50 H58A50-N54 VanDerWaalsContact O-CB 3.31Å; A50-N54 WeakPolarHBondContact O-CB 3.35Å; A50-N54 VanDerWaalsContact O-CG 3.27Å; A50-N54 PolarHBondContact O-N 2.96Å; A50-N54 VanDerWaalsContact O-N 3.13Å; A50-N54 PolarHBondContact O-ND2 3.24Å; N54-H58 VanDerWaalsContact O-CB 3.24Å; N54-H58 WeakPolarHBondContact O-CB 3.22Å; N54-H58 PolarHBondContact O-N 3.26Å
55L81.9Confident83.1Confident4 Ų450 Ų502%0.02128%0.277CS..Hα-helixtrans-67.2-44.3176.7-178.554.9000112.1C51 S52 L53 H58 G59 W118 A131 T135C51-L55 WeakPolarHBondContact O-CB 3.26Å; C51-L55 PolarHBondContact O-N 3.47Å; S52-L55 WeakPolarHBondContact O-CB 3.48Å; S52-L55 PolarHBondContact O-N 2.98Å; L53-L55 PolarHBondContact O-N 3.3Å; L55-H58 PolarHBondContact O-N 2.98Å; L55-G59 PolarHBondContact O-N 2.75Å; L55-W118 HydrophobicContact CB-CH2 4.4Å; L55-W118 HydrophobicContact CB-CZ2 3.71Å; L55-W118 HydrophobicContact CD1-CD2 4.41Å; L55-W118 HydrophobicContact CD1-CE3 4.31Å; L55-W118 HydrophobicContact CD1-CH2 3.69Å; L55-W118 HydrophobicContact CD1-CZ2 3.76Å; L55-W118 HydrophobicContact CD1-CZ3 3.96Å; L55-W118 HydrophobicContact CD2-CH2 3.82Å; L55-W118 HydrophobicContact CD2-CZ2 3.89Å; L55-W118 HydrophobicContact CG-CH2 4.18Å; L55-W118 HydrophobicContact CG-CZ2 3.99Å; L55-A131 HydrophobicContact CD2-CB 3.7Å; L55-T135 HydrophobicContact CD1-CG2 4.23Å; L55-T135 WeakPolarHBondContact CD1-OG1 3.45Å
56V84.1Confident83.8Confident10 Ų1048.2 Ų48.26%0.06127%0.27CS..Hα-helixtrans-64.6-43.1177.1168.40000111.2L40 Y45 S52 L53 G59 R60L40-V56 HydrophobicContact CD2-CB 4.48Å; L40-V56 HydrophobicContact CD2-CG1 4.38Å; L40-V56 HydrophobicContact CD2-CG2 4.48Å; Y45-V56 HydrophobicContact CD1-CG2 3.6Å; Y45-V56 HydrophobicContact CD2-CG2 3.61Å; Y45-V56 HydrophobicContact CE1-CG2 3.81Å; Y45-V56 HydrophobicContact CE2-CG2 3.84Å; Y45-V56 HydrophobicContact CG-CG2 3.46Å; Y45-V56 VanDerWaalsContact CG-CG2 3.46Å; S52-V56 WeakPolarHBondContact O-CG2 3.4Å; S52-V56 PolarHBondContact O-N 3Å; L53-V56 PolarHBondContact O-N 3.1Å; V56-G59 PolarHBondContact O-N 2.82Å; V56-R60 VanDerWaalsContact O-CG 3.28Å; V56-R60 WeakPolarHBondContact O-CG 3.32Å; V56-R60 PolarHBondContact O-N 3.15Å
57D84.7Confident84.7Confident73 Ų7348 Ų4839%0.3927%0.269SS..Hα-helixtrans-72.3-32.6178.7-72.3-27.5000112.9L53 R60 G61L53-D57 PolarHBondContact O-N 2.96Å; D57-R60 PolarHBondContact O-N 3.21Å; D57-R60 WeakPolarHBondContact OD1-CD 3.47Å; D57-R60 IonicContact OD1-CZ 3.73Å; D57-R60 IonicContact OD1-NE 3.31Å; D57-R60 IonicContact OD1-NH1 3.96Å; D57-R60 PolarHBondContact OD1-NH1 2.92Å; D57-G61 PolarHBondContact O-N 3.35Å
58H86.2Confident85.8Confident12 Ų1246 Ų466%0.05626%0.256CS..Hα-helixtrans-63.1-43.7168.2-176.172.9000111.8N54 L55 G61 Y62 Y111N54-H58 VanDerWaalsContact O-CB 3.24Å; N54-H58 WeakPolarHBondContact O-CB 3.22Å; N54-H58 PolarHBondContact O-N 3.26Å; L55-H58 PolarHBondContact O-N 2.98Å; H58-G61 PolarHBondContact O-N 3.45Å; H58-Y62 PolarHBondContact O-N 3.24Å; H58-Y111 WeakPolarHBondContact CA-OH 3.46Å; H58-Y111 AromaticContact CE1-CD1 3.52Å; H58-Y111 AromaticContact CE1-CE1 3.24Å; H58-Y111 WeakPolarHBondContact CE1-CE1 3.46Å; H58-Y111 AromaticContact CG-CE1 3.98Å; H58-Y111 AromaticContact ND1-CD1 3.96Å; H58-Y111 AromaticContact ND1-CE1 3.23Å; H58-Y111 WeakPolarHBondContact ND1-CE1 3.37Å; H58-Y111 AromaticContact ND1-CZ 3.72Å; H58-Y111 AromaticContact NE2-CE1 3.97Å; H58-Y111 WeakPolarHBondContact O-CE1 3.13Å; H58-Y111 PolarHBondContact O-OH 3.22Å; H58-Y111 VanDerWaalsContact O-OH 3.05Å
59G87.8Confident86.9Confident4 Ų437.3 Ų37.34%0.04122%0.216CC..Hα-helixtrans-63-44175.100000112.8L40 L55 V56 G61 Y62 L63L40-G59 VanDerWaalsContact CD1-C 3.46Å; L55-G59 PolarHBondContact O-N 2.75Å; V56-G59 PolarHBondContact O-N 2.82Å; G59-G61 PolarHBondContact O-N 3.48Å; G59-Y62 PolarHBondContact O-N 2.99Å; G59-L63 WeakPolarHBondContact O-CB 3.39Å; G59-L63 PolarHBondContact O-N 3.36Å
60R89.4Confident87.6Confident134 Ų13436 Ų3651%0.50621%0.211SC..Hα-helixtrans-59.2-44.8176.2-74.8165.2176162.80112.2V56 D57 L63 G64V56-R60 VanDerWaalsContact O-CG 3.28Å; V56-R60 WeakPolarHBondContact O-CG 3.32Å; V56-R60 PolarHBondContact O-N 3.15Å; D57-R60 PolarHBondContact O-N 3.21Å; D57-R60 WeakPolarHBondContact OD1-CD 3.47Å; D57-R60 IonicContact OD1-CZ 3.73Å; D57-R60 IonicContact OD1-NE 3.31Å; D57-R60 IonicContact OD1-NH1 3.96Å; D57-R60 PolarHBondContact OD1-NH1 2.92Å; R60-L63 PolarHBondContact O-N 2.67Å; R60-G64 PolarHBondContact O-N 3.46Å
61G90.3Very high88.5Confident29 Ų2938.1 Ų38.130%0.29921%0.211SC..Hα-helixtrans-64.4-43.3176.700000112.5D57 H58 G59 L63 G64 I65 Y111D57-G61 PolarHBondContact O-N 3.35Å; H58-G61 PolarHBondContact O-N 3.45Å; G59-G61 PolarHBondContact O-N 3.48Å; G61-L63 VanDerWaalsContact C-N 3.35Å; G61-L63 PolarHBondContact O-N 3.47Å; G61-G64 PolarHBondContact O-N 3.33Å; G61-I65 PolarHBondContact O-N 3.04Å; G61-Y111 WeakPolarHBondContact CA-OH 3.42Å
62Y90.6Very high89.2Confident11 Ų1137.9 Ų37.94%0.04321%0.21CC..Hα-helixtrans-66.4-34.2176.7-164-106.8000113.2L36 H58 G59 G64 I65 L66 Y111 M138 N142L36-Y62 HydrophobicContact CD2-CD1 3.87Å; H58-Y62 PolarHBondContact O-N 3.24Å; G59-Y62 PolarHBondContact O-N 2.99Å; Y62-G64 VanDerWaalsContact C-N 3.27Å; Y62-G64 PolarHBondContact O-N 3.37Å; Y62-I65 HydrophobicContact CD2-CD1 4.39Å; Y62-I65 WeakPolarHBondContact O-CB 3.39Å; Y62-I65 PolarHBondContact O-N 3.33Å; Y62-I65 VanDerWaalsContact O-N 3.07Å; Y62-L66 HydrophobicContact CD1-CD1 3.74Å; Y62-L66 HydrophobicContact CD1-CD2 4.47Å; Y62-L66 HydrophobicContact CD1-CG 3.84Å; Y62-L66 HydrophobicContact CE1-CD1 3.69Å; Y62-L66 HydrophobicContact CE1-CD2 3.75Å; Y62-L66 HydrophobicContact CE1-CG 3.62Å; Y62-L66 PolarHBondContact O-N 2.62Å; Y62-Y111 AromaticContact CD2-CD1 3.74Å; Y62-Y111 HydrophobicContact CD2-CD1 3.74Å; Y62-Y111 HydrophobicContact CD2-CE1 4.3Å; Y62-Y111 HydrophobicContact CG-CD1 4.42Å; Y62-M138 HydrophobicContact CD1-CE 3.78Å; Y62-M138 HydrophobicContact CD1-CG 4.03Å; Y62-M138 HydrophobicContact CD1-SD 3.3Å; Y62-M138 WeakPolarHBondContact CD1-SD 3.43Å; Y62-M138 HydrophobicContact CE1-CE 4.15Å; Y62-M138 HydrophobicContact CE1-CG 3.56Å; Y62-M138 HydrophobicContact CE1-SD 3.51Å; Y62-M138 VanDerWaalsContact CE1-SD 3.51Å; Y62-M138 HydrophobicContact CG-CE 3.98Å; Y62-M138 HydrophobicContact CG-SD 4.11Å; Y62-N142 WeakPolarHBondContact CE2-ND2 3.47Å; Y62-N142 PolarHBondContact OH-ND2 3.35Å
63L91.9Very high89.9Confident26 Ų2637.9 Ų37.914%0.13621%0.21CC..Hα-helixtrans-59.7-37.8174.4-16771.2000111.9F33 L36 S37 F41 G59 R60 G61 L67F33-L63 HydrophobicContact CD1-CD1 4.48Å; F33-L63 HydrophobicContact CD2-CD1 3.43Å; F33-L63 VanDerWaalsContact CD2-CD1 3.43Å; F33-L63 HydrophobicContact CD2-CG 4.08Å; F33-L63 HydrophobicContact CE2-CD1 3.48Å; F33-L63 VanDerWaalsContact CE2-CD1 3.48Å; F33-L63 HydrophobicContact CE2-CG 3.69Å; F33-L63 HydrophobicContact CG-CD1 3.95Å; F33-L63 HydrophobicContact CZ-CD1 4.05Å; F33-L63 HydrophobicContact CZ-CG 4.3Å; L36-L63 HydrophobicContact CB-CD1 4.38Å; L36-L63 HydrophobicContact CD2-CB 4.19Å; L36-L63 HydrophobicContact CD2-CD1 4.18Å; L36-L63 HydrophobicContact CG-CD1 4.32Å; S37-L63 WeakPolarHBondContact OG-CD1 3.37Å; F41-L63 HydrophobicContact CE2-CD2 4.21Å; G59-L63 WeakPolarHBondContact O-CB 3.39Å; G59-L63 PolarHBondContact O-N 3.36Å; R60-L63 PolarHBondContact O-N 2.67Å; G61-L63 VanDerWaalsContact C-N 3.35Å; G61-L63 PolarHBondContact O-N 3.47Å; L63-L67 PolarHBondContact O-N 3.08Å
64G93.2Very high90.5Very high37 Ų3738.4 Ų38.438%0.38121%0.212SC..Hα-helixtrans-68.4-33.8172.600000113.9R60 G61 Y62 S68R60-G64 PolarHBondContact O-N 3.46Å; G61-G64 PolarHBondContact O-N 3.33Å; Y62-G64 VanDerWaalsContact C-N 3.27Å; Y62-G64 PolarHBondContact O-N 3.37Å; G64-S68 WeakPolarHBondContact O-CB 3.49Å; G64-S68 PolarHBondContact O-N 3.31Å; G64-S68 VanDerWaalsContact O-N 3.1Å; G64-S68 PolarHBondContact O-OG 3.18Å
65I92.7Very high91Very high16 Ų1636.8 Ų36.88%0.08221%0.208CC..Hα-helixtrans-67.6-48.5172.8-64.1171.2000110.2G61 Y62 L67 S68 C69 I107 E108 Y111G61-I65 PolarHBondContact O-N 3.04Å; Y62-I65 HydrophobicContact CD2-CD1 4.39Å; Y62-I65 WeakPolarHBondContact O-CB 3.39Å; Y62-I65 PolarHBondContact O-N 3.33Å; Y62-I65 VanDerWaalsContact O-N 3.07Å; I65-L67 VanDerWaalsContact C-N 3.34Å; I65-L67 PolarHBondContact O-N 3.31Å; I65-S68 CarbonylContact O-C 3.33Å; I65-S68 WeakPolarHBondContact O-CA 3.43Å; I65-S68 WeakPolarHBondContact O-CB 3.44Å; I65-S68 PolarHBondContact O-N 2.89Å; I65-C69 PolarHBondContact O-N 2.86Å; I65-C69 PolarHBondContact O-SG 3.48Å; I65-C69 VanDerWaalsContact O-SG 3.34Å; I65-I107 HydrophobicContact CD1-CG2 4.09Å; I65-I107 HydrophobicContact CG1-CG2 4.39Å; I65-E108 HydrophobicContact CG2-CB 4.21Å; I65-E108 HydrophobicContact CG2-CG 4.44Å; I65-Y111 HydrophobicContact CD1-CD1 4.05Å; I65-Y111 HydrophobicContact CD1-CD2 3.54Å; I65-Y111 HydrophobicContact CD1-CE2 4.2Å; I65-Y111 HydrophobicContact CD1-CG 3.45Å; I65-Y111 VanDerWaalsContact CD1-CG 3.45Å
66L92.9Very high91.5Very high1 Ų137.1 Ų37.11%0.00521%0.21CC..Hα-helixtrans-56.6-44.7176.6-72.6175.3000112.2H29 W32 F33 L36 Y62 S68 C69 M70H29-L66 HydrophobicContact CB-CD2 4.13Å; W32-L66 HydrophobicContact CB-CD1 4.18Å; F33-L66 HydrophobicContact CB-CB 4.49Å; F33-L66 HydrophobicContact CB-CD1 4.28Å; F33-L66 HydrophobicContact CD2-CB 4.09Å; L36-L66 HydrophobicContact CD2-CD1 4.14Å; Y62-L66 HydrophobicContact CD1-CD1 3.74Å; Y62-L66 HydrophobicContact CD1-CD2 4.47Å; Y62-L66 HydrophobicContact CD1-CG 3.84Å; Y62-L66 HydrophobicContact CE1-CD1 3.69Å; Y62-L66 HydrophobicContact CE1-CD2 3.75Å; Y62-L66 HydrophobicContact CE1-CG 3.62Å; Y62-L66 PolarHBondContact O-N 2.62Å; L66-S68 VanDerWaalsContact C-N 3.29Å; L66-S68 PolarHBondContact O-N 3.37Å; L66-C69 WeakPolarHBondContact O-CB 3.21Å; L66-C69 PolarHBondContact O-N 3.48Å; L66-M70 WeakPolarHBondContact O-CB 3.46Å; L66-M70 WeakPolarHBondContact O-CG 3.16Å; L66-M70 PolarHBondContact O-N 2.84Å
67L94.4Very high91.8Very high82 Ų8237.3 Ų37.343%0.42921%0.211SC..Hα-helixtrans-60.4-39.8174.7-178.361.1000111.8F33 L63 I65 M70 I71F33-L67 HydrophobicContact CE2-CB 4.1Å; L63-L67 PolarHBondContact O-N 3.08Å; I65-L67 VanDerWaalsContact C-N 3.34Å; I65-L67 PolarHBondContact O-N 3.31Å; L67-M70 PolarHBondContact O-N 2.91Å; L67-I71 HydrophobicContact CD1-CD1 4.23Å; L67-I71 HydrophobicContact CG-CD1 4.06Å; L67-I71 VanDerWaalsContact O-CG1 3.29Å; L67-I71 WeakPolarHBondContact O-CG1 3.3Å; L67-I71 PolarHBondContact O-N 3.39Å
68S94Very high92.1Very high53 Ų5340.5 Ų40.537%0.37122%0.217SC..Hα-helixtrans-66.9-40.8176.8-56.60000112.2G64 I65 L66 A72G64-S68 WeakPolarHBondContact O-CB 3.49Å; G64-S68 PolarHBondContact O-N 3.31Å; G64-S68 VanDerWaalsContact O-N 3.1Å; G64-S68 PolarHBondContact O-OG 3.18Å; I65-S68 CarbonylContact O-C 3.33Å; I65-S68 WeakPolarHBondContact O-CA 3.43Å; I65-S68 WeakPolarHBondContact O-CB 3.44Å; I65-S68 PolarHBondContact O-N 2.89Å; L66-S68 VanDerWaalsContact C-N 3.29Å; L66-S68 PolarHBondContact O-N 3.37Å; S68-A72 WeakPolarHBondContact O-CB 3.36Å; S68-A72 PolarHBondContact O-N 3.42Å; S68-A72 VanDerWaalsContact O-N 3.08Å
69C93.4Very high92.2Very high0 Ų040.7 Ų40.70%022%0.218CC..Hα-helixtrans-59.8-49.8172.3-65.60000110.8I65 L66 I71 A72 E73 R101 I104I65-C69 PolarHBondContact O-N 2.86Å; I65-C69 PolarHBondContact O-SG 3.48Å; I65-C69 VanDerWaalsContact O-SG 3.34Å; L66-C69 WeakPolarHBondContact O-CB 3.21Å; L66-C69 PolarHBondContact O-N 3.48Å; C69-I71 PolarHBondContact O-N 3.1Å; C69-A72 PolarHBondContact O-N 2.83Å; C69-E73 WeakPolarHBondContact O-CB 3.45Å; C69-E73 VanDerWaalsContact O-CD 3.29Å; C69-E73 WeakPolarHBondContact O-CG 3.3Å; C69-E73 PolarHBondContact O-N 3.12Å; C69-R101 VanDerWaalsContact SG-CZ 3.56Å; C69-R101 PolarHBondContact SG-NH2 3.25Å; C69-R101 VanDerWaalsContact SG-NH2 3.39Å; C69-I104 WeakPolarHBondContact SG-CG2 3.38Å
70M94.3Very high92.2Very high29 Ų2940.5 Ų40.514%0.14322%0.217CC..Hα-helixtrans-59.3-42.2179.3-74173.263.500112.9F26 H29 T30 F33 L66 L67 E73 M74F26-M70 HydrophobicContact CD2-CB 4.07Å; F26-M70 HydrophobicContact CD2-CG 4.11Å; F26-M70 HydrophobicContact CE2-CB 3.9Å; F26-M70 HydrophobicContact CE2-CE 3.83Å; F26-M70 HydrophobicContact CE2-CG 4.09Å; F26-M70 HydrophobicContact CZ-CE 4.05Å; H29-M70 HydrophobicContact CB-CG 3.85Å; T30-M70 HydrophobicContact CG2-CE 4.34Å; T30-M70 WeakPolarHBondContact OG1-CE 3.47Å; F33-M70 HydrophobicContact CB-SD 4.08Å; F33-M70 HydrophobicContact CD2-SD 4.39Å; F33-M70 HydrophobicContact CG-SD 4.24Å; L66-M70 WeakPolarHBondContact O-CB 3.46Å; L66-M70 WeakPolarHBondContact O-CG 3.16Å; L66-M70 PolarHBondContact O-N 2.84Å; L67-M70 PolarHBondContact O-N 2.91Å; M70-E73 PolarHBondContact O-N 3.49Å; M70-M74 WeakPolarHBondContact O-CB 3.42Å; M70-M74 WeakPolarHBondContact O-CG 3.38Å; M70-M74 PolarHBondContact O-N 3.47Å
71I95.1Very high92Very high109 Ų10937.6 Ų37.656%0.55921%0.21SC*.Hα-helixtrans-64.5-45176.1-69.2164.7000110.9L67 C69 A75L67-I71 HydrophobicContact CD1-CD1 4.23Å; L67-I71 HydrophobicContact CG-CD1 4.06Å; L67-I71 VanDerWaalsContact O-CG1 3.29Å; L67-I71 WeakPolarHBondContact O-CG1 3.3Å; L67-I71 PolarHBondContact O-N 3.39Å; C69-I71 PolarHBondContact O-N 3.1Å; I71-A75 PolarHBondContact O-N 2.89Å
72A93.1Very high91.7Very high7 Ų741.3 Ų41.36%0.05822%0.215CC..Hα-helixtrans-65.8-39.3178.200000112.2S68 C69 A75 I76 R101 I104S68-A72 WeakPolarHBondContact O-CB 3.36Å; S68-A72 PolarHBondContact O-N 3.42Å; S68-A72 VanDerWaalsContact O-N 3.08Å; C69-A72 PolarHBondContact O-N 2.83Å; A72-A75 PolarHBondContact O-N 3.04Å; A72-I76 WeakPolarHBondContact O-CG1 3.32Å; A72-I76 PolarHBondContact O-N 3.49Å; A72-R101 HydrophobicContact CB-CB 4.36Å; A72-I104 HydrophobicContact CB-CD1 3.9Å
73E94.1Very high91.3Very high1 Ų142 Ų421%0.00523%0.225CC..Hα-helixtrans-69.3-40.9178-76.9149.1-158.500111.8L25 F26 H29 C69 M70 A75 I76 I77 R101L25-E73 HydrophobicContact CB-CG 4.45Å; F26-E73 HydrophobicContact CB-CB 4.27Å; F26-E73 PolarHBondContact N-OE2 2.96Å; H29-E73 IonicContact CE1-OE1 3.97Å; H29-E73 PolarHBondContact CE1-OE1 3.14Å; H29-E73 VanDerWaalsContact CE1-OE1 3.23Å; H29-E73 IonicContact CE1-OE2 3.96Å; H29-E73 IonicContact CG-OE2 3.42Å; H29-E73 IonicContact ND1-OE1 3.51Å; H29-E73 PolarHBondContact ND1-OE1 2.96Å; H29-E73 IonicContact ND1-OE2 2.83Å; H29-E73 PolarHBondContact ND1-OE2 3.42Å; C69-E73 WeakPolarHBondContact O-CB 3.45Å; C69-E73 VanDerWaalsContact O-CD 3.29Å; C69-E73 WeakPolarHBondContact O-CG 3.3Å; C69-E73 PolarHBondContact O-N 3.12Å; M70-E73 PolarHBondContact O-N 3.49Å; E73-A75 VanDerWaalsContact C-N 3.3Å; E73-A75 PolarHBondContact O-N 2.89Å; E73-I76 PolarHBondContact O-N 3.39Å; E73-I76 VanDerWaalsContact O-N 3.16Å; E73-I77 VanDerWaalsContact O-CG1 3.23Å; E73-I77 WeakPolarHBondContact O-CG1 3.29Å; E73-I77 PolarHBondContact O-N 3.29Å; E73-R101 IonicContact OE1-CZ 2.77Å; E73-R101 VanDerWaalsContact OE1-CZ 3.25Å; E73-R101 IonicContact OE1-NE 3.91Å; E73-R101 PolarHBondContact OE1-NE 2.88Å; E73-R101 IonicContact OE1-NH2 3.02Å; E73-R101 PolarHBondContact OE1-NH2 2.9Å
74M93.5Very high90.7Very high96 Ų9641 Ų4147%0.47322%0.221SC..Hα-helixtrans-60.3-38.1170.6-75.3-63.3-68.600112.5F26 M70 I77 W78F26-M74 HydrophobicContact CD1-SD 4.46Å; F26-M74 HydrophobicContact CD2-CG 3.74Å; F26-M74 HydrophobicContact CD2-SD 4.01Å; F26-M74 HydrophobicContact CE1-SD 4.2Å; F26-M74 HydrophobicContact CE2-CG 3.38Å; F26-M74 HydrophobicContact CE2-SD 3.72Å; F26-M74 HydrophobicContact CG-SD 4.38Å; F26-M74 HydrophobicContact CZ-CG 4.03Å; F26-M74 HydrophobicContact CZ-SD 3.83Å; M70-M74 WeakPolarHBondContact O-CB 3.42Å; M70-M74 WeakPolarHBondContact O-CG 3.38Å; M70-M74 PolarHBondContact O-N 3.47Å; M74-I77 PolarHBondContact O-N 3.08Å; M74-I77 HydrophobicContact SD-CD1 4.26Å; M74-W78 VanDerWaalsContact O-CB 3.25Å; M74-W78 WeakPolarHBondContact O-CB 3.35Å; M74-W78 PolarHBondContact O-N 3.2Å
75A93.4Very high89.9Confident38 Ų3839.3 Ų39.331%0.31420%0.203SC..Hα-helixtrans-66.6-38.4174.100000112.5I71 A72 E73 L79 V97I71-A75 PolarHBondContact O-N 2.89Å; A72-A75 PolarHBondContact O-N 3.04Å; E73-A75 VanDerWaalsContact C-N 3.3Å; E73-A75 PolarHBondContact O-N 2.89Å; A75-L79 WeakPolarHBondContact O-CB 3.32Å; A75-L79 WeakPolarHBondContact O-CG 3.38Å; A75-L79 PolarHBondContact O-N 2.95Å; A75-L79 VanDerWaalsContact O-N 3.09Å; A75-V97 HydrophobicContact CB-CG1 3.99Å
76I91.6Very high89.1Confident11 Ų1142.7 Ų42.76%0.05622%0.221CC..Hα-helixtrans-62.9-52.5172.8-67.4165.1000109.9L18 A22 A72 E73 W78 L79 S80 M94 V97 L98 R101L18-I76 HydrophobicContact CB-CG2 3.84Å; L18-I76 HydrophobicContact CD1-CG2 4.5Å; A22-I76 HydrophobicContact CB-CB 4.21Å; A22-I76 HydrophobicContact CB-CG2 3.78Å; A72-I76 WeakPolarHBondContact O-CG1 3.32Å; A72-I76 PolarHBondContact O-N 3.49Å; E73-I76 PolarHBondContact O-N 3.39Å; E73-I76 VanDerWaalsContact O-N 3.16Å; I76-W78 PolarHBondContact O-N 2.93Å; I76-L79 PolarHBondContact O-N 3.25Å; I76-S80 VanDerWaalsContact O-CB 3.26Å; I76-S80 WeakPolarHBondContact O-CB 3.36Å; I76-S80 PolarHBondContact O-N 2.92Å; I76-S80 PolarHBondContact O-OG 2.88Å; I76-S80 VanDerWaalsContact O-OG 3.09Å; I76-M94 HydrophobicContact CG1-SD 4.36Å; I76-M94 HydrophobicContact CG2-CE 4.24Å; I76-M94 HydrophobicContact CG2-SD 4.31Å; I76-V97 HydrophobicContact CD1-CG1 4.5Å; I76-V97 HydrophobicContact CG1-CG1 3.68Å; I76-L98 HydrophobicContact CD1-CD2 4.43Å; I76-R101 HydrophobicContact CD1-CB 4.31Å; I76-R101 HydrophobicContact CD1-CG 4.38Å
77I91Very high88.4Confident15 Ų1548.4 Ų48.48%0.07724%0.243CC..Hα-helixtrans-54.5-51.4179.3-65.6162.5000110.5A22 I23 F26 E73 M74 L79 S80 M81A22-I77 HydrophobicContact CB-CD1 4.26Å; A22-I77 HydrophobicContact CB-CG1 3.61Å; I23-I77 HydrophobicContact CG1-CD1 3.81Å; I23-I77 HydrophobicContact CG1-CG1 3.98Å; I23-I77 HydrophobicContact CG1-CG2 4.35Å; F26-I77 HydrophobicContact CB-CD1 4.2Å; E73-I77 VanDerWaalsContact O-CG1 3.23Å; E73-I77 WeakPolarHBondContact O-CG1 3.29Å; E73-I77 PolarHBondContact O-N 3.29Å; M74-I77 PolarHBondContact O-N 3.08Å; M74-I77 HydrophobicContact SD-CD1 4.26Å; I77-L79 PolarHBondContact O-N 3.02Å; I77-S80 PolarHBondContact O-N 3.04Å; I77-M81 HydrophobicContact CG2-CE 3.8Å; I77-M81 HydrophobicContact CG2-CG 4.47Å; I77-M81 HydrophobicContact CG2-SD 4.1Å; I77-M81 WeakPolarHBondContact O-CB 3.47Å; I77-M81 VanDerWaalsContact O-CG 3.27Å; I77-M81 WeakPolarHBondContact O-CG 3.24Å; I77-M81 PolarHBondContact O-N 2.85Å
78W90.4Very high87.7Confident140 Ų14046.3 Ų46.353%0.5323%0.234SC..Hα-helixtrans-63.1-36.4-177.9-176.690.8000113.7M74 I76 R82M74-W78 VanDerWaalsContact O-CB 3.25Å; M74-W78 WeakPolarHBondContact O-CB 3.35Å; M74-W78 PolarHBondContact O-N 3.2Å; I76-W78 PolarHBondContact O-N 2.93Å; W78-R82 VanDerWaalsContact CH2-CZ 3.46Å; W78-R82 VanDerWaalsContact CZ2-CZ 3.4Å; W78-R82 WeakPolarHBondContact O-CD 3.27Å; W78-R82 WeakPolarHBondContact O-CG 3.21Å
79L89.9Confident87.1Confident15 Ų1549.5 Ų49.58%0.07924%0.243CC..Hα-helixtrans-74.4-49.5173.2-72.8177.2000111.7A75 I76 I77 M81 R82 R91 M94 V97A75-L79 WeakPolarHBondContact O-CB 3.32Å; A75-L79 WeakPolarHBondContact O-CG 3.38Å; A75-L79 PolarHBondContact O-N 2.95Å; A75-L79 VanDerWaalsContact O-N 3.09Å; I76-L79 PolarHBondContact O-N 3.25Å; I77-L79 PolarHBondContact O-N 3.02Å; L79-M81 PolarHBondContact O-N 3.1Å; L79-R82 WeakPolarHBondContact O-CB 3.48Å; L79-R82 PolarHBondContact O-N 2.98Å; L79-R91 WeakPolarHBondContact O-CG 3.29Å; L79-M94 HydrophobicContact CB-CE 3.54Å; L79-M94 HydrophobicContact CD1-CE 4.28Å; L79-V97 HydrophobicContact CD1-CB 4.47Å; L79-V97 HydrophobicContact CD1-CG2 3.64Å
80S87.1Confident86.6Confident1 Ų151.3 Ų51.31%0.00726%0.255CS..Hα-helixtrans-62.7-26.4-175.9-67.80000113.8S15 V19 I76 I77 R82 M94S15-S80 VanDerWaalsContact O-CB 3.24Å; S15-S80 WeakPolarHBondContact O-CB 3.5Å; S15-S80 PolarHBondContact O-OG 2.84Å; V19-S80 VanDerWaalsContact CG2-CB 3.4Å; I76-S80 VanDerWaalsContact O-CB 3.26Å; I76-S80 WeakPolarHBondContact O-CB 3.36Å; I76-S80 PolarHBondContact O-N 2.92Å; I76-S80 PolarHBondContact O-OG 2.88Å; I76-S80 VanDerWaalsContact O-OG 3.09Å; I77-S80 PolarHBondContact O-N 3.04Å; S80-R82 VanDerWaalsContact C-N 3.26Å; S80-R82 PolarHBondContact O-N 3.19Å; S80-M94 WeakPolarHBondContact OG-CE 3.13Å
81M85.1Confident86.1Confident72 Ų7250.3 Ų50.336%0.35525%0.25SC..THydrogen-bonded Turntrans-73.2-9.9173.7-72-171.6-55.200114.5V19 I77 L79 W553V19-M81 HydrophobicContact CG1-CG 4.26Å; V19-M81 HydrophobicContact CG2-CG 4.02Å; I77-M81 HydrophobicContact CG2-CE 3.8Å; I77-M81 HydrophobicContact CG2-CG 4.47Å; I77-M81 HydrophobicContact CG2-SD 4.1Å; I77-M81 WeakPolarHBondContact O-CB 3.47Å; I77-M81 VanDerWaalsContact O-CG 3.27Å; I77-M81 WeakPolarHBondContact O-CG 3.24Å; I77-M81 PolarHBondContact O-N 2.85Å; L79-M81 PolarHBondContact O-N 3.1Å; M81-W553 HydrophobicContact SD-CZ2 4.42Å
82R84.2Confident85.5Confident108 Ų10849.7 Ų49.741%0.40825%0.247SC..SBendtrans-93140-172.4-69.8171.4162.1-132.2-14.3114W78 L79 S80 P90 R91W78-R82 VanDerWaalsContact CH2-CZ 3.46Å; W78-R82 VanDerWaalsContact CZ2-CZ 3.4Å; W78-R82 WeakPolarHBondContact O-CD 3.27Å; W78-R82 WeakPolarHBondContact O-CG 3.21Å; L79-R82 WeakPolarHBondContact O-CB 3.48Å; L79-R82 PolarHBondContact O-N 2.98Å; S80-R82 VanDerWaalsContact C-N 3.26Å; S80-R82 PolarHBondContact O-N 3.19Å; R82-P90 HydrophobicContact CB-CB 4.08Å; R82-P90 HydrophobicContact CB-CG 4.36Å; R82-R91 WeakPolarHBondContact O-CD 3.38Å; R82-R91 WeakPolarHBondContact O-CG 3.43Å; R82-R91 PolarHBondContact O-NE 3.44Å
83G82Confident85.2Confident25 Ų2552.6 Ų52.626%0.25827%0.267SS..SBendtrans84.1167.9178.500000114P551G83-P551 WeakPolarHBondContact O-CA 3.29Å; G83-P551 WeakPolarHBondContact O-CB 3.4Å
84G79.3Confident84.9Confident5 Ų552.6 Ų52.65%0.05227%0.267CS..  trans-88.3170.917100000112L86 Y87 R91 T549 K550G84-L86 VanDerWaalsContact C-N 3.32Å; G84-L86 PolarHBondContact O-N 3.36Å; G84-Y87 CarbonylContact O-C 3.57Å; G84-Y87 PolarHBondContact O-N 3.44Å; G84-Y87 VanDerWaalsContact O-O 3.11Å; G84-R91 PolarHBondContact O-NH2 3.45Å; G84-T549 WeakPolarHBondContact CA-O 3.36Å; G84-K550 WeakPolarHBondContact CA-O 3.47Å
85I77.1Confident84.6Confident1 Ų151.1 Ų51.11%0.00526%0.259CS..THydrogen-bonded Turntrans-56-42.6-171.7-33.4175.8000112.5M1 D235 A238 L242 L545 K552 I555M1-I85 HydrophobicContact CE-CB 3.67Å; M1-I85 HydrophobicContact CE-CG2 3.56Å; M1-I85 HydrophobicContact CG-CG2 3.91Å; M1-I85 WeakPolarHBondContact CG-O 3.46Å; M1-I85 HydrophobicContact SD-CB 4.48Å; M1-I85 HydrophobicContact SD-CG2 3.72Å; I85-D235 WeakPolarHBondContact CG2-OD1 3.3Å; I85-A238 HydrophobicContact CD1-CB 4.06Å; I85-L242 HydrophobicContact CD1-CD1 4.42Å; I85-L545 HydrophobicContact CD1-CD2 3.64Å; I85-K552 HydrophobicContact CG1-CB 4.43Å; I85-K552 HydrophobicContact CG2-CD 4.47Å; I85-I555 HydrophobicContact CD1-CD1 3.71Å; I85-I555 HydrophobicContact CG1-CD1 4.06Å
86L74.7Confident84.4Confident87 Ų8756.6 Ų56.646%0.45527%0.273SS..THydrogen-bonded Turntrans-79.3-22.9173-78.9173000114.7M1 G84 T88 Q546M1-L86 HydrophobicContact CE-CD2 3.89Å; M1-L86 HydrophobicContact CE-CG 3.67Å; M1-L86 HydrophobicContact CG-CD2 4.04Å; G84-L86 VanDerWaalsContact C-N 3.32Å; G84-L86 PolarHBondContact O-N 3.36Å; L86-T88 PolarHBondContact O-N 3.43Å; L86-Q546 HydrophobicContact CD1-CB 4.37Å; L86-Q546 HydrophobicContact CD1-CG 4.09Å
87Y79.6Confident84.4Confident121 Ų12157.4 Ų57.448%0.47528%0.278SS..  trans-91.893.3-172.2-172.5-120.4000110.6G84 E89 P90 R91G84-Y87 CarbonylContact O-C 3.57Å; G84-Y87 PolarHBondContact O-N 3.44Å; G84-Y87 VanDerWaalsContact O-O 3.11Å; Y87-E89 HydrophobicContact CE2-CB 4.06Å; Y87-E89 HydrophobicContact CE2-CG 3.97Å; Y87-E89 WeakPolarHBondContact CE2-OE2 3.3Å; Y87-E89 PolarHBondContact OH-OE2 3.45Å; Y87-P90 HydrophobicContact CD1-CG 3.93Å; Y87-P90 VanDerWaalsContact CE1-CD 3.41Å; Y87-P90 HydrophobicContact CE1-CG 3.74Å; Y87-R91 PolarHBondContact O-NH2 3.46Å
88T79.4Confident84.3Confident38 Ų3858.8 Ų58.823%0.23329%0.285CS..  trans-94.9-21.4-171580000115.1P2 L86 P90 R91P2-T88 HydrophobicContact CG-CG2 4.36Å; L86-T88 PolarHBondContact O-N 3.43Å; T88-P90 VanDerWaalsContact C-CD 3.46Å; T88-R91 WeakPolarHBondContact O-CA 3.46Å; T88-R91 WeakPolarHBondContact O-CB 3.4Å; T88-R91 PolarHBondContact O-N 3.49Å
89E81.2Confident84.3Confident121 Ų12155.9 Ų55.957%0.56528%0.275SS*.G310 helixtrans-45.3-47.6-177-60.1178.5165.800115Y87 R91 D92Y87-E89 HydrophobicContact CE2-CB 4.06Å; Y87-E89 HydrophobicContact CE2-CG 3.97Å; Y87-E89 WeakPolarHBondContact CE2-OE2 3.3Å; Y87-E89 PolarHBondContact OH-OE2 3.45Å; E89-R91 PolarHBondContact O-N 3.39Å; E89-D92 PolarHBondContact O-N 3.25Å; E89-D92 VanDerWaalsContact O-N 3.11Å
90P82.9Confident84.4Confident38 Ų3859.1 Ų59.125%0.24730%0.295CS..G310 helixtrans-68.90.1179.729.6-38.4000114.3R82 Y87 T88R82-P90 HydrophobicContact CB-CB 4.08Å; R82-P90 HydrophobicContact CB-CG 4.36Å; Y87-P90 HydrophobicContact CD1-CG 3.93Å; Y87-P90 VanDerWaalsContact CE1-CD 3.41Å; Y87-P90 HydrophobicContact CE1-CG 3.74Å; T88-P90 VanDerWaalsContact C-CD 3.46Å
91R83.3Confident84.6Confident8 Ų860.3 Ų60.33%0.0330%0.299CS..G310 helixtrans-113.62.1177.4-66.6173.3-77.4154.7-15.8113.1S15 D16 L79 R82 G84 Y87 T88 E89 S93 M94S15-R91 WeakPolarHBondContact OG-CD 3.48Å; S15-R91 PolarHBondContact OG-NH1 3.18Å; S15-R91 VanDerWaalsContact OG-NH1 3.14Å; D16-R91 IonicContact OD1-NH1 2.86Å; D16-R91 IonicContact OD2-CZ 3.94Å; D16-R91 IonicContact OD2-NH1 2.81Å; D16-R91 PolarHBondContact OD2-NH1 3.37Å; D16-R91 IonicContact OD2-NH2 2.73Å; L79-R91 WeakPolarHBondContact O-CG 3.29Å; R82-R91 WeakPolarHBondContact O-CD 3.38Å; R82-R91 WeakPolarHBondContact O-CG 3.43Å; R82-R91 PolarHBondContact O-NE 3.44Å; G84-R91 PolarHBondContact O-NH2 3.45Å; Y87-R91 PolarHBondContact O-NH2 3.46Å; T88-R91 WeakPolarHBondContact O-CA 3.46Å; T88-R91 WeakPolarHBondContact O-CB 3.4Å; T88-R91 PolarHBondContact O-N 3.49Å; E89-R91 PolarHBondContact O-N 3.39Å; R91-S93 PolarHBondContact O-N 3.04Å; R91-S93 VanDerWaalsContact O-N 3.15Å; R91-M94 WeakPolarHBondContact O-CB 3.42Å; R91-M94 PolarHBondContact O-N 3.18Å
92D82.8Confident84.8Confident96 Ų9660.6 Ų60.651%0.51330%0.302SS..THydrogen-bonded Turntrans-62-24.9-177.4-76.5-7.2000113.4E89 M94 Q95E89-D92 PolarHBondContact O-N 3.25Å; E89-D92 VanDerWaalsContact O-N 3.11Å; D92-M94 VanDerWaalsContact C-N 3.26Å; D92-M94 PolarHBondContact O-N 2.78Å; D92-Q95 PolarHBondContact O-NE2 3.33Å
93S87.6Confident85.2Confident67 Ų6758 Ų5847%0.46930%0.303SS..THydrogen-bonded Turntrans-69.4-16.4173-52.40000114.3R91 Q95 Y96R91-S93 PolarHBondContact O-N 3.04Å; R91-S93 VanDerWaalsContact O-N 3.15Å; S93-Q95 PolarHBondContact O-N 2.77Å; S93-Q95 VanDerWaalsContact O-N 3.16Å; S93-Y96 PolarHBondContact O-N 3.17Å
94M86.9Confident85.7Confident1 Ų157.9 Ų57.91%0.00530%0.297CS..Hα-helixtrans-55.1-36.7-175.3179.657.464.200112.9I4 L18 I76 L79 S80 R91 D92 Y96 V97 L98I4-M94 HydrophobicContact CD1-CB 4.35Å; I4-M94 HydrophobicContact CD1-CG 3.69Å; L18-M94 HydrophobicContact CD1-CE 4.49Å; L18-M94 HydrophobicContact CD1-CG 4.16Å; L18-M94 HydrophobicContact CD1-SD 3.83Å; I76-M94 HydrophobicContact CG1-SD 4.36Å; I76-M94 HydrophobicContact CG2-CE 4.24Å; I76-M94 HydrophobicContact CG2-SD 4.31Å; L79-M94 HydrophobicContact CB-CE 3.54Å; L79-M94 HydrophobicContact CD1-CE 4.28Å; S80-M94 WeakPolarHBondContact OG-CE 3.13Å; R91-M94 WeakPolarHBondContact O-CB 3.42Å; R91-M94 PolarHBondContact O-N 3.18Å; D92-M94 VanDerWaalsContact C-N 3.26Å; D92-M94 PolarHBondContact O-N 2.78Å; M94-Y96 PolarHBondContact O-N 3.44Å; M94-V97 PolarHBondContact O-N 3.43Å; M94-L98 HydrophobicContact CG-CD1 3.9Å; M94-L98 HydrophobicContact CG-CG 4.21Å; M94-L98 WeakPolarHBondContact O-CG 3.46Å; M94-L98 PolarHBondContact O-N 3.39Å; M94-L98 HydrophobicContact SD-CD1 4.27Å; M94-L98 HydrophobicContact SD-CD2 4.48Å; M94-L98 HydrophobicContact SD-CG 3.99Å
95Q87.5Confident86.2Confident66 Ų6659.2 Ų59.231%0.30830%0.302SS..Hα-helixtrans-56.1-36.817968.5-170.9-57.600112.7D92 S93 Y99D92-Q95 PolarHBondContact O-NE2 3.33Å; S93-Q95 PolarHBondContact O-N 2.77Å; S93-Q95 VanDerWaalsContact O-N 3.16Å; Q95-Y99 HydrophobicContact CB-CE2 4.4Å; Q95-Y99 WeakPolarHBondContact O-CD2 3.13Å; Q95-Y99 WeakPolarHBondContact O-CE2 3.44Å; Q95-Y99 VanDerWaalsContact O-CG 3.32Å; Q95-Y99 PolarHBondContact O-N 3.49Å
96Y89.8Confident86.9Confident152 Ų15263 Ų6360%0.59633%0.326SS*.Hα-helixtrans-75.4-41.7-179-58.5-75.8000111.6S93 M94 L98 Y99 V100S93-Y96 PolarHBondContact O-N 3.17Å; M94-Y96 PolarHBondContact O-N 3.44Å; Y96-L98 VanDerWaalsContact C-N 3.29Å; Y96-L98 PolarHBondContact O-N 3.25Å; Y96-Y99 PolarHBondContact O-N 2.95Å; Y96-V100 WeakPolarHBondContact O-CG2 3.49Å; Y96-V100 PolarHBondContact O-N 2.91Å
97V90.3Very high87.8Confident29 Ų2963.4 Ų63.418%0.17633%0.327CS..Hα-helixtrans-64.1-36.4176.7-174.30000111A75 I76 L79 M94 V100 R101A75-V97 HydrophobicContact CB-CG1 3.99Å; I76-V97 HydrophobicContact CD1-CG1 4.5Å; I76-V97 HydrophobicContact CG1-CG1 3.68Å; L79-V97 HydrophobicContact CD1-CB 4.47Å; L79-V97 HydrophobicContact CD1-CG2 3.64Å; M94-V97 PolarHBondContact O-N 3.43Å; V97-V100 PolarHBondContact O-N 2.99Å; V97-R101 PolarHBondContact O-N 3.27Å
98L88.7Confident88.3Confident44 Ų4457.7 Ų57.723%0.2331%0.305CS..Hα-helixtrans-66.3-37.3173-71.6174000113.3I4 V6 L18 I76 M94 Y96 V100 L102I4-L98 HydrophobicContact CD1-CD1 3.55Å; V6-L98 HydrophobicContact CG2-CD1 4.28Å; L18-L98 HydrophobicContact CD1-CD1 4.12Å; L18-L98 HydrophobicContact CD1-CD2 4.13Å; I76-L98 HydrophobicContact CD1-CD2 4.43Å; M94-L98 HydrophobicContact CG-CD1 3.9Å; M94-L98 HydrophobicContact CG-CG 4.21Å; M94-L98 WeakPolarHBondContact O-CG 3.46Å; M94-L98 PolarHBondContact O-N 3.39Å; M94-L98 HydrophobicContact SD-CD1 4.27Å; M94-L98 HydrophobicContact SD-CD2 4.48Å; M94-L98 HydrophobicContact SD-CG 3.99Å; Y96-L98 VanDerWaalsContact C-N 3.29Å; Y96-L98 PolarHBondContact O-N 3.25Å; L98-V100 VanDerWaalsContact C-N 3.31Å; L98-L102 WeakPolarHBondContact O-CB 3.35Å; L98-L102 PolarHBondContact O-N 3.06Å
99Y90.8Very high88.8Confident78 Ų7860 Ų6031%0.30631%0.312SS..Hα-helixtrans-64.2-37.2171.8-62.2-45.6000111.6V6 F7 Q95 Y96 A103V6-Y99 HydrophobicContact CG1-CD1 4.22Å; V6-Y99 HydrophobicContact CG1-CE1 3.4Å; F7-Y99 AromaticContact CD1-CE1 3.86Å; F7-Y99 HydrophobicContact CD1-CE1 3.86Å; F7-Y99 HydrophobicContact CD2-CE1 4.32Å; F7-Y99 AromaticContact CE1-CD1 3.85Å; F7-Y99 HydrophobicContact CE1-CD1 3.85Å; F7-Y99 AromaticContact CE1-CE1 3.49Å; F7-Y99 HydrophobicContact CE1-CE1 3.49Å; F7-Y99 VanDerWaalsContact CE1-CE1 3.49Å; F7-Y99 HydrophobicContact CE2-CD1 4.37Å; F7-Y99 AromaticContact CE2-CE1 3.99Å; F7-Y99 HydrophobicContact CE2-CE1 3.99Å; F7-Y99 HydrophobicContact CG-CE1 4.25Å; F7-Y99 AromaticContact CZ-CD1 3.68Å; F7-Y99 HydrophobicContact CZ-CD1 3.68Å; F7-Y99 AromaticContact CZ-CE1 3.55Å; F7-Y99 HydrophobicContact CZ-CE1 3.55Å; F7-Y99 PolarHBondContact N-OH 3.06Å; F7-Y99 VanDerWaalsContact N-OH 3.13Å; Q95-Y99 HydrophobicContact CB-CE2 4.4Å; Q95-Y99 WeakPolarHBondContact O-CD2 3.13Å; Q95-Y99 WeakPolarHBondContact O-CE2 3.44Å; Q95-Y99 VanDerWaalsContact O-CG 3.32Å; Q95-Y99 PolarHBondContact O-N 3.49Å; Y96-Y99 PolarHBondContact O-N 2.95Å; Y99-A103 PolarHBondContact O-N 3.12Å; Y99-A103 VanDerWaalsContact O-N 3.1Å
100V91.5Very high89.4Confident83 Ų8358.8 Ų58.850%0.50331%0.308SS..Hα-helixtrans-66.9-48.6174.8174.40000111.7Y96 V97 L98 L102 A103 I104Y96-V100 WeakPolarHBondContact O-CG2 3.49Å; Y96-V100 PolarHBondContact O-N 2.91Å; V97-V100 PolarHBondContact O-N 2.99Å; L98-V100 VanDerWaalsContact C-N 3.31Å; V100-L102 VanDerWaalsContact C-N 3.27Å; V100-L102 PolarHBondContact O-N 2.89Å; V100-A103 WeakPolarHBondContact O-CB 3.3Å; V100-A103 PolarHBondContact O-N 3.05Å; V100-A103 VanDerWaalsContact O-N 3.11Å; V100-I104 HydrophobicContact CG1-CD1 4.06Å; V100-I104 WeakPolarHBondContact O-CG1 3.42Å; V100-I104 PolarHBondContact O-N 3.48Å
101R91.3Very high89.7Confident26 Ų2659.4 Ų59.410%0.09831%0.306CS..Hα-helixtrans-64.2-31.6177.9-174.257.6176.2106.5-12.1112.4H29 C69 A72 E73 I76 V97 I104 L105 E108H29-R101 PolarHBondContact CE1-NH2 3.44Å; C69-R101 VanDerWaalsContact SG-CZ 3.56Å; C69-R101 PolarHBondContact SG-NH2 3.25Å; C69-R101 VanDerWaalsContact SG-NH2 3.39Å; A72-R101 HydrophobicContact CB-CB 4.36Å; E73-R101 IonicContact OE1-CZ 2.77Å; E73-R101 VanDerWaalsContact OE1-CZ 3.25Å; E73-R101 IonicContact OE1-NE 3.91Å; E73-R101 PolarHBondContact OE1-NE 2.88Å; E73-R101 IonicContact OE1-NH2 3.02Å; E73-R101 PolarHBondContact OE1-NH2 2.9Å; I76-R101 HydrophobicContact CD1-CB 4.31Å; I76-R101 HydrophobicContact CD1-CG 4.38Å; V97-R101 PolarHBondContact O-N 3.27Å; R101-I104 PolarHBondContact O-N 2.92Å; R101-L105 WeakPolarHBondContact O-CB 3.44Å; R101-L105 PolarHBondContact O-N 2.82Å; R101-E108 IonicContact CZ-OE2 3.62Å; R101-E108 IonicContact NH1-OE2 2.67Å; R101-E108 PolarHBondContact NH1-OE2 2.99Å; R101-E108 IonicContact NH2-OE1 3.21Å; R101-E108 IonicContact NH2-OE2 3.76Å; R101-E108 PolarHBondContact NH2-OE2 3.17Å
102L90.1Very high90Very high78 Ų7859.2 Ų59.241%0.40831%0.306SS..Hα-helixtrans-66.2-40.9171.9-178.265.1000112.2F7 L98 V100 I104 L105 V106F7-L102 HydrophobicContact CE2-CD2 4.21Å; F7-L102 HydrophobicContact CZ-CD2 3.58Å; L98-L102 WeakPolarHBondContact O-CB 3.35Å; L98-L102 PolarHBondContact O-N 3.06Å; V100-L102 VanDerWaalsContact C-N 3.27Å; V100-L102 PolarHBondContact O-N 2.89Å; L102-I104 VanDerWaalsContact C-N 3.33Å; L102-L105 HydrophobicContact CD1-CD2 4.34Å; L102-L105 PolarHBondContact O-N 3.17Å; L102-V106 WeakPolarHBondContact O-CG2 3.19Å; L102-V106 PolarHBondContact O-N 2.9Å; L102-V106 VanDerWaalsContact O-N 3.08Å
103A92.3Very high90.4Very high53 Ų5358.2 Ų58.244%0.43830%0.3SS..Hα-helixtrans-62.8-41.5174.700000111.5Y99 V100 V106 I107Y99-A103 PolarHBondContact O-N 3.12Å; Y99-A103 VanDerWaalsContact O-N 3.1Å; V100-A103 WeakPolarHBondContact O-CB 3.3Å; V100-A103 PolarHBondContact O-N 3.05Å; V100-A103 VanDerWaalsContact O-N 3.11Å; A103-V106 PolarHBondContact O-N 3.01Å; A103-I107 WeakPolarHBondContact O-CG1 3.44Å; A103-I107 PolarHBondContact O-N 3.28Å
104I92.3Very high90.5Very high24 Ų2458.3 Ų58.312%0.12330%0.298CS..Hα-helixtrans-61.3-43.8173.1-63.8166.8000110.8C69 A72 V100 R101 L102 V106 I107 E108C69-I104 WeakPolarHBondContact SG-CG2 3.38Å; A72-I104 HydrophobicContact CB-CD1 3.9Å; V100-I104 HydrophobicContact CG1-CD1 4.06Å; V100-I104 WeakPolarHBondContact O-CG1 3.42Å; V100-I104 PolarHBondContact O-N 3.48Å; R101-I104 PolarHBondContact O-N 2.92Å; L102-I104 VanDerWaalsContact C-N 3.33Å; I104-V106 VanDerWaalsContact C-N 3.29Å; I104-V106 PolarHBondContact O-N 3.35Å; I104-I107 WeakPolarHBondContact O-CB 3.42Å; I104-I107 PolarHBondContact O-N 3.45Å; I104-I107 VanDerWaalsContact O-N 3.1Å; I104-E108 VanDerWaalsContact O-CB 3.29Å; I104-E108 WeakPolarHBondContact O-CB 3.4Å; I104-E108 PolarHBondContact O-N 3.49Å
105L90.4Very high90.5Very high32 Ų3258.2 Ų58.217%0.16830%0.297CS..Hα-helixtrans-61.3-33.3178.2-175.167.1000113R101 L102 F109 I146 V149R101-L105 WeakPolarHBondContact O-CB 3.44Å; R101-L105 PolarHBondContact O-N 2.82Å; L102-L105 HydrophobicContact CD1-CD2 4.34Å; L102-L105 PolarHBondContact O-N 3.17Å; L105-F109 WeakPolarHBondContact O-CB 3.5Å; L105-F109 PolarHBondContact O-N 3.04Å; L105-I146 HydrophobicContact CD1-CG1 4.22Å; L105-V149 HydrophobicContact CD2-CG1 3.83Å
106V91.4Very high90.6Very high81 Ų8158.4 Ų58.449%0.49130%0.3SS..Hα-helixtrans-70.1-39.5174.2172.90000111.3L102 A103 I104 I110L102-V106 WeakPolarHBondContact O-CG2 3.19Å; L102-V106 PolarHBondContact O-N 2.9Å; L102-V106 VanDerWaalsContact O-N 3.08Å; A103-V106 PolarHBondContact O-N 3.01Å; I104-V106 VanDerWaalsContact C-N 3.29Å; I104-V106 PolarHBondContact O-N 3.35Å; V106-I110 HydrophobicContact CG1-CD1 4.2Å; V106-I110 WeakPolarHBondContact O-CG1 3.35Å; V106-I110 PolarHBondContact O-N 3.49Å; V106-I110 VanDerWaalsContact O-N 3.13Å
107I92.8Very high90.6Very high96 Ų9654.3 Ų54.349%0.49229%0.29SS..Hα-helixtrans-65.2-44.4174.3-64166.1000110.2I65 A103 I104 F109 I110 Y111I65-I107 HydrophobicContact CD1-CG2 4.09Å; I65-I107 HydrophobicContact CG1-CG2 4.39Å; A103-I107 WeakPolarHBondContact O-CG1 3.44Å; A103-I107 PolarHBondContact O-N 3.28Å; I104-I107 WeakPolarHBondContact O-CB 3.42Å; I104-I107 PolarHBondContact O-N 3.45Å; I104-I107 VanDerWaalsContact O-N 3.1Å; I107-F109 PolarHBondContact O-N 2.71Å; I107-I110 PolarHBondContact O-N 2.99Å; I107-Y111 WeakPolarHBondContact O-CB 3.39Å; I107-Y111 PolarHBondContact O-N 3.2Å
108E91.3Very high90.4Very high1 Ų153.6 Ų53.61%0.00528%0.284CS..Hα-helixtrans-58-44.7176.5-176.8169.8-149.100111.9H29 I65 R101 I104 Y111 A112 N142H29-E108 IonicContact NE2-OE1 3.27Å; I65-E108 HydrophobicContact CG2-CB 4.21Å; I65-E108 HydrophobicContact CG2-CG 4.44Å; R101-E108 IonicContact CZ-OE2 3.62Å; R101-E108 IonicContact NH1-OE2 2.67Å; R101-E108 PolarHBondContact NH1-OE2 2.99Å; R101-E108 IonicContact NH2-OE1 3.21Å; R101-E108 IonicContact NH2-OE2 3.76Å; R101-E108 PolarHBondContact NH2-OE2 3.17Å; I104-E108 VanDerWaalsContact O-CB 3.29Å; I104-E108 WeakPolarHBondContact O-CB 3.4Å; I104-E108 PolarHBondContact O-N 3.49Å; E108-Y111 PolarHBondContact O-N 2.8Å; E108-A112 WeakPolarHBondContact O-CB 3.45Å; E108-A112 PolarHBondContact O-N 2.78Å; E108-N142 WeakPolarHBondContact CG-ND2 3.49Å
109F90.6Very high90.2Very high85 Ų8552.6 Ų52.637%0.37328%0.279SS..Hα-helixtrans-61.9-44.6173.6176-99.3000112.9L105 I107 Y111 A112 I113 W143 I146L105-F109 WeakPolarHBondContact O-CB 3.5Å; L105-F109 PolarHBondContact O-N 3.04Å; I107-F109 PolarHBondContact O-N 2.71Å; F109-Y111 VanDerWaalsContact C-N 3.3Å; F109-Y111 PolarHBondContact O-N 3.46Å; F109-A112 PolarHBondContact O-N 3.02Å; F109-I113 HydrophobicContact CD1-CD1 4.06Å; F109-I113 HydrophobicContact CE1-CD1 3.59Å; F109-I113 HydrophobicContact CZ-CD1 3.88Å; F109-I113 WeakPolarHBondContact O-CG1 3.26Å; F109-I113 PolarHBondContact O-N 3.18Å; F109-I113 VanDerWaalsContact O-N 3.17Å; F109-W143 HydrophobicContact CD2-CH2 4.2Å; F109-W143 AromaticContact CE2-CH2 3.57Å; F109-W143 HydrophobicContact CE2-CH2 3.57Å; F109-W143 HydrophobicContact CE2-CZ2 4.42Å; F109-W143 AromaticContact CE2-CZ3 3.97Å; F109-W143 HydrophobicContact CE2-CZ3 3.97Å; F109-W143 HydrophobicContact CZ-CH2 4.34Å; F109-I146 HydrophobicContact CB-CD1 4.1Å; F109-I146 HydrophobicContact CD2-CD1 4.13Å; F109-I146 HydrophobicContact CD2-CG2 4.36Å
110I92.2Very high89.9Confident97 Ų9754.2 Ų54.250%0.49730%0.297SS..Hα-helixtrans-62.5-41175.6-67164.7000110.2V106 I107 I113 V114V106-I110 HydrophobicContact CG1-CD1 4.2Å; V106-I110 WeakPolarHBondContact O-CG1 3.35Å; V106-I110 PolarHBondContact O-N 3.49Å; V106-I110 VanDerWaalsContact O-N 3.13Å; I107-I110 PolarHBondContact O-N 2.99Å; I110-I113 WeakPolarHBondContact O-CB 3.31Å; I110-I113 PolarHBondContact O-N 3.14Å; I110-V114 PolarHBondContact O-N 3.26Å; I110-V114 VanDerWaalsContact O-N 3.11Å
111Y90.8Very high89.5Confident51 Ų5155.4 Ų55.420%0.230%0.297CS..Hα-helixtrans-68.1-36.2179.1-142-91.2000112.8H58 G61 Y62 I65 I107 E108 F109 I113 V114 G115H58-Y111 WeakPolarHBondContact CA-OH 3.46Å; H58-Y111 AromaticContact CE1-CD1 3.52Å; H58-Y111 AromaticContact CE1-CE1 3.24Å; H58-Y111 WeakPolarHBondContact CE1-CE1 3.46Å; H58-Y111 AromaticContact CG-CE1 3.98Å; H58-Y111 AromaticContact ND1-CD1 3.96Å; H58-Y111 AromaticContact ND1-CE1 3.23Å; H58-Y111 WeakPolarHBondContact ND1-CE1 3.37Å; H58-Y111 AromaticContact ND1-CZ 3.72Å; H58-Y111 AromaticContact NE2-CE1 3.97Å; H58-Y111 WeakPolarHBondContact O-CE1 3.13Å; H58-Y111 PolarHBondContact O-OH 3.22Å; H58-Y111 VanDerWaalsContact O-OH 3.05Å; G61-Y111 WeakPolarHBondContact CA-OH 3.42Å; Y62-Y111 AromaticContact CD2-CD1 3.74Å; Y62-Y111 HydrophobicContact CD2-CD1 3.74Å; Y62-Y111 HydrophobicContact CD2-CE1 4.3Å; Y62-Y111 HydrophobicContact CG-CD1 4.42Å; I65-Y111 HydrophobicContact CD1-CD1 4.05Å; I65-Y111 HydrophobicContact CD1-CD2 3.54Å; I65-Y111 HydrophobicContact CD1-CE2 4.2Å; I65-Y111 HydrophobicContact CD1-CG 3.45Å; I65-Y111 VanDerWaalsContact CD1-CG 3.45Å; I107-Y111 WeakPolarHBondContact O-CB 3.39Å; I107-Y111 PolarHBondContact O-N 3.2Å; E108-Y111 PolarHBondContact O-N 2.8Å; F109-Y111 VanDerWaalsContact C-N 3.3Å; F109-Y111 PolarHBondContact O-N 3.46Å; Y111-I113 VanDerWaalsContact C-N 3.3Å; Y111-I113 PolarHBondContact O-N 2.93Å; Y111-V114 PolarHBondContact O-N 2.73Å; Y111-G115 PolarHBondContact O-N 2.95Å
112A89.1Confident89Confident4 Ų457.7 Ų57.73%0.03331%0.307CS..Hα-helixtrans-64.2-33.3173.600000112.5E108 F109 G115 I116E108-A112 WeakPolarHBondContact O-CB 3.45Å; E108-A112 PolarHBondContact O-N 2.78Å; F109-A112 PolarHBondContact O-N 3.02Å; A112-G115 PolarHBondContact O-N 3.42Å; A112-I116 PolarHBondContact O-N 3.28Å; A112-I116 VanDerWaalsContact O-N 3.15Å
113I90.3Very high88.4Confident74 Ų7458 Ų5838%0.37930%0.303SS..Hα-helixtrans-67.2-44.3170.9-66.2167.2000110.7F109 I110 Y111 G115 I116 V117 W143F109-I113 HydrophobicContact CD1-CD1 4.06Å; F109-I113 HydrophobicContact CE1-CD1 3.59Å; F109-I113 HydrophobicContact CZ-CD1 3.88Å; F109-I113 WeakPolarHBondContact O-CG1 3.26Å; F109-I113 PolarHBondContact O-N 3.18Å; F109-I113 VanDerWaalsContact O-N 3.17Å; I110-I113 WeakPolarHBondContact O-CB 3.31Å; I110-I113 PolarHBondContact O-N 3.14Å; Y111-I113 VanDerWaalsContact C-N 3.3Å; Y111-I113 PolarHBondContact O-N 2.93Å; I113-G115 VanDerWaalsContact C-N 3.26Å; I113-G115 PolarHBondContact O-N 3.25Å; I113-I116 PolarHBondContact O-N 3.2Å; I113-I116 VanDerWaalsContact O-N 3.12Å; I113-V117 WeakPolarHBondContact O-CG2 3.45Å; I113-V117 PolarHBondContact O-N 3Å; I113-W143 HydrophobicContact CG1-CZ2 4.19Å
114V89.9Confident87.6Confident69 Ų6961.6 Ų61.642%0.41832%0.32SS..Hα-helixtrans-59.4-38.3174.7175.40000111.3I110 Y111 V117 W118I110-V114 PolarHBondContact O-N 3.26Å; I110-V114 VanDerWaalsContact O-N 3.11Å; Y111-V114 PolarHBondContact O-N 2.73Å; V114-V117 PolarHBondContact O-N 3.14Å; V114-W118 PolarHBondContact O-N 3.31Å
115G87.8Confident86.8Confident0 Ų064.1 Ų64.10%034%0.339CS..Hα-helixtrans-60.5-41.9173.200000113.4Y111 A112 I113 W118 L119Y111-G115 PolarHBondContact O-N 2.95Å; A112-G115 PolarHBondContact O-N 3.42Å; I113-G115 VanDerWaalsContact C-N 3.26Å; I113-G115 PolarHBondContact O-N 3.25Å; G115-W118 PolarHBondContact O-N 3.33Å; G115-L119 WeakPolarHBondContact O-CB 3.38Å; G115-L119 VanDerWaalsContact O-CG 3.29Å; G115-L119 WeakPolarHBondContact O-CG 3.22Å; G115-L119 PolarHBondContact O-N 3.46Å
116I89.3Confident86Confident70 Ų7062.6 Ų62.636%0.35933%0.331SS..Hα-helixtrans-64.8-40.4173.2-69.8175.5000111.5A112 I113 L119 T120 V139 W143A112-I116 PolarHBondContact O-N 3.28Å; A112-I116 VanDerWaalsContact O-N 3.15Å; I113-I116 PolarHBondContact O-N 3.2Å; I113-I116 VanDerWaalsContact O-N 3.12Å; I116-L119 PolarHBondContact O-N 2.8Å; I116-T120 HydrophobicContact CG2-CG2 4.34Å; I116-T120 WeakPolarHBondContact O-CB 3.44Å; I116-T120 WeakPolarHBondContact O-CG2 3.31Å; I116-T120 PolarHBondContact O-N 3.34Å; I116-T120 PolarHBondContact O-OG1 3.28Å; I116-V139 HydrophobicContact CG1-CG1 3.89Å; I116-W143 HydrophobicContact CD1-CZ2 4.01Å; I116-W143 VanDerWaalsContact CD1-NE1 3.33Å
117V88.7Confident85.2Confident65 Ų6564.9 Ų64.939%0.39434%0.341SS..Hα-helixtrans-63.9-42.1176.9174.80000110.8I113 V114 T120 Q121I113-V117 WeakPolarHBondContact O-CG2 3.45Å; I113-V117 PolarHBondContact O-N 3Å; V114-V117 PolarHBondContact O-N 3.14Å; V117-T120 PolarHBondContact O-OG1 3.47Å; V117-T120 VanDerWaalsContact O-OG1 3.12Å; V117-Q121 WeakPolarHBondContact O-CB 3.17Å; V117-Q121 VanDerWaalsContact O-CG 3.31Å; V117-Q121 WeakPolarHBondContact O-CG 3.48Å; V117-Q121 PolarHBondContact O-N 2.92Å
118W86.5Confident84.4Confident15 Ų1562 Ų626%0.05733%0.326CS..Hα-helixtrans-63.7-46.9174.7-175.291.2000111.8L55 V114 G115 T120 Q121 Y122 K132 T135L55-W118 HydrophobicContact CB-CH2 4.4Å; L55-W118 HydrophobicContact CB-CZ2 3.71Å; L55-W118 HydrophobicContact CD1-CD2 4.41Å; L55-W118 HydrophobicContact CD1-CE3 4.31Å; L55-W118 HydrophobicContact CD1-CH2 3.69Å; L55-W118 HydrophobicContact CD1-CZ2 3.76Å; L55-W118 HydrophobicContact CD1-CZ3 3.96Å; L55-W118 HydrophobicContact CD2-CH2 3.82Å; L55-W118 HydrophobicContact CD2-CZ2 3.89Å; L55-W118 HydrophobicContact CG-CH2 4.18Å; L55-W118 HydrophobicContact CG-CZ2 3.99Å; V114-W118 PolarHBondContact O-N 3.31Å; G115-W118 PolarHBondContact O-N 3.33Å; W118-T120 PolarHBondContact O-N 3.3Å; W118-Q121 PolarHBondContact O-N 3.3Å; W118-Y122 AromaticContact CD1-CD2 3.69Å; W118-Y122 HydrophobicContact CG-CD2 4.18Å; W118-Y122 AromaticContact NE1-CD2 3.81Å; W118-Y122 WeakPolarHBondContact O-CB 3.27Å; W118-Y122 PolarHBondContact O-N 3.46Å; W118-K132 HydrophobicContact CH2-CB 4.4Å; W118-T135 HydrophobicContact CE3-CG2 4.25Å; W118-T135 HydrophobicContact CZ3-CG2 4.34Å
119L85.3Confident83.8Confident22 Ų2267.2 Ų67.212%0.11535%0.353CS..Hα-helixtrans-59-45.4177.9-74.8166.9000112G115 I116 Q121 Y123 L136 V139G115-L119 WeakPolarHBondContact O-CB 3.38Å; G115-L119 VanDerWaalsContact O-CG 3.29Å; G115-L119 WeakPolarHBondContact O-CG 3.22Å; G115-L119 PolarHBondContact O-N 3.46Å; I116-L119 PolarHBondContact O-N 2.8Å; L119-Q121 VanDerWaalsContact C-N 3.3Å; L119-Q121 PolarHBondContact O-N 3.24Å; L119-Y123 HydrophobicContact CD2-CD2 3.79Å; L119-Y123 WeakPolarHBondContact O-CB 3.3Å; L119-Y123 PolarHBondContact O-N 3.38Å; L119-L136 HydrophobicContact CD1-CD1 4.06Å; L119-L136 HydrophobicContact CD2-CB 4.29Å; L119-L136 HydrophobicContact CD2-CD1 4.45Å; L119-V139 HydrophobicContact CD1-CB 4.09Å; L119-V139 HydrophobicContact CD1-CG1 4.17Å; L119-V139 HydrophobicContact CD1-CG2 4.03Å
120T85Confident83.2Confident112 Ų11267.3 Ų67.369%0.68736%0.361SS*.Hα-helixtrans-69.3-24.3-179.649.60000113.8I116 V117 W118I116-T120 HydrophobicContact CG2-CG2 4.34Å; I116-T120 WeakPolarHBondContact O-CB 3.44Å; I116-T120 WeakPolarHBondContact O-CG2 3.31Å; I116-T120 PolarHBondContact O-N 3.34Å; I116-T120 PolarHBondContact O-OG1 3.28Å; V117-T120 PolarHBondContact O-OG1 3.47Å; V117-T120 VanDerWaalsContact O-OG1 3.12Å; W118-T120 PolarHBondContact O-N 3.3Å
121Q82.9Confident82.5Confident109 Ų10962.7 Ų62.751%0.50934%0.338SS..Hα-helixtrans-91-33.6178.3-70.1177.61.600114.1V117 W118 L119V117-Q121 WeakPolarHBondContact O-CB 3.17Å; V117-Q121 VanDerWaalsContact O-CG 3.31Å; V117-Q121 WeakPolarHBondContact O-CG 3.48Å; V117-Q121 PolarHBondContact O-N 2.92Å; W118-Q121 PolarHBondContact O-N 3.3Å; L119-Q121 VanDerWaalsContact C-N 3.3Å; L119-Q121 PolarHBondContact O-N 3.24Å
122Y79.7Confident81.9Confident74 Ų7461.8 Ų61.829%0.2934%0.335SS..Hα-helixtrans-126.7-10.7-162.8-65.5-71.9000116.3C51 W118 T124 S125 C126C51-Y122 HydrophobicContact CB-CD1 4.28Å; W118-Y122 AromaticContact CD1-CD2 3.69Å; W118-Y122 HydrophobicContact CG-CD2 4.18Å; W118-Y122 AromaticContact NE1-CD2 3.81Å; W118-Y122 WeakPolarHBondContact O-CB 3.27Å; W118-Y122 PolarHBondContact O-N 3.46Å; Y122-T124 VanDerWaalsContact C-N 3.31Å; Y122-T124 PolarHBondContact O-N 2.95Å; Y122-S125 PolarHBondContact O-N 2.87Å; Y122-C126 PolarHBondContact O-N 3Å
123Y77.6Confident81.7Confident85 Ų8565.3 Ų65.333%0.33335%0.353SS..THydrogen-bonded Turntrans-60.6-34.3-173.6-179.6-99.3000114.6L119 K132 L136L119-Y123 HydrophobicContact CD2-CD2 3.79Å; L119-Y123 WeakPolarHBondContact O-CB 3.3Å; L119-Y123 PolarHBondContact O-N 3.38Å; Y123-K132 HydrophobicContact CD2-CB 4.2Å; Y123-K132 HydrophobicContact CD2-CD 4.28Å; Y123-K132 HydrophobicContact CD2-CG 4.34Å; Y123-K132 HydrophobicContact CE2-CB 4.39Å; Y123-K132 HydrophobicContact CE2-CD 4.4Å; Y123-K132 HydrophobicContact CE2-CG 4.2Å; Y123-K132 WeakPolarHBondContact O-CD 3.48Å; Y123-K132 PolarHBondContact O-NZ 3.03Å; Y123-L136 HydrophobicContact CE2-CB 4.45Å; Y123-L136 HydrophobicContact CE2-CD2 4.05Å
124T76.9Confident81.5Confident128 Ų12863.1 Ų63.179%0.78534%0.343SS*.THydrogen-bonded Turntrans-79.4-24.2173.946.20000113.4Y122Y122-T124 VanDerWaalsContact C-N 3.31Å; Y122-T124 PolarHBondContact O-N 2.95Å
125S73.4Confident81.2Confident76 Ų7660.2 Ų60.253%0.53133%0.326SS..THydrogen-bonded Turntrans-96.4-20.9-171.5-53.40000114Y122Y122-S125 PolarHBondContact O-N 2.87Å
126C75.6Confident81.1Confident1 Ų163.3 Ų63.31%0.00734%0.342CS..  trans-84.2131.1176-111.90000112.3C51 Y122 K132C51-C126 HydrophobicContact CB-CB 4.35Å; C51-C126 WeakPolarHBondContact CB-SG 3.44Å; C51-C126 WeakPolarHBondContact SG-CB 3.43Å; C51-C126 CovalentContact SG-SG 2.03Å; C51-C126 PolarHBondContact SG-SG 2.89Å; Y122-C126 PolarHBondContact O-N 3Å; C126-K132 PolarHBondContact O-NZ 3.35Å
127N74.3Confident81Confident128 Ų12861.3 Ų61.368%0.68434%0.339SS*.  trans-78.4-18.6174.5-67.5-50.1000113.6L129N127-L129 VanDerWaalsContact C-N 3.3Å; N127-L129 PolarHBondContact O-N 3.06Å
128D75.8Confident81Confident36 Ų3658.4 Ų58.419%0.19332%0.321CS..  trans-69.374.9-175.9-64.6-31.6000113S52 T130 A131 K132S52-D128 WeakPolarHBondContact CB-OD2 3.34Å; S52-D128 PolarHBondContact OG-OD2 3.05Å; D128-T130 PolarHBondContact O-N 2.96Å; D128-A131 HydrophobicContact CB-CB 4.05Å; D128-A131 PolarHBondContact O-N 3.05Å; D128-K132 WeakPolarHBondContact O-CG 3.45Å; D128-K132 PolarHBondContact O-N 3.28Å
129L77.5Confident81.1Confident110 Ų11058.2 Ų58.258%0.57632%0.321SS*.Hα-helixtrans-55.3-46.3-172.4-178.860.6000113.5N127 N133N127-L129 VanDerWaalsContact C-N 3.3Å; N127-L129 PolarHBondContact O-N 3.06Å; L129-N133 WeakPolarHBondContact O-CB 3.48Å; L129-N133 PolarHBondContact O-N 2.77Å; L129-N133 PolarHBondContact O-ND2 2.98Å; L129-N133 PolarHBondContact O-OD1 2.89Å
130T78.4Confident81.3Confident87 Ų8761.2 Ų61.253%0.53434%0.34SS..Hα-helixtrans-64.3-46.1179.4-50.30000111.3L43 D128 V134L43-T130 HydrophobicContact CD1-CG2 4.34Å; D128-T130 PolarHBondContact O-N 2.96Å; T130-V134 WeakPolarHBondContact O-CG2 3.26Å; T130-V134 PolarHBondContact O-N 3.41Å; T130-V134 VanDerWaalsContact O-N 3.1Å
131A77Confident81.6Confident1 Ų157.3 Ų57.31%0.00832%0.317CS..Hα-helixtrans-66.9-45.9-176.700000111.5V39 Y45 L55 D128 N133 V134 T135V39-A131 HydrophobicContact CG1-CB 4.35Å; Y45-A131 HydrophobicContact CE1-CB 4.13Å; L55-A131 HydrophobicContact CD2-CB 3.7Å; D128-A131 HydrophobicContact CB-CB 4.05Å; D128-A131 PolarHBondContact O-N 3.05Å; A131-N133 VanDerWaalsContact C-N 3.34Å; A131-N133 PolarHBondContact O-N 3.19Å; A131-V134 PolarHBondContact O-N 2.92Å; A131-T135 PolarHBondContact O-N 2.88Å; A131-T135 PolarHBondContact O-OG1 2.88Å
132K79.6Confident81.9Confident31 Ų3152.4 Ų52.414%0.13529%0.294CS..Hα-helixtrans-66.4-33.4179.873.5-173.1-177.6-179.70113.5W118 Y123 C126 D128 L136W118-K132 HydrophobicContact CH2-CB 4.4Å; Y123-K132 HydrophobicContact CD2-CB 4.2Å; Y123-K132 HydrophobicContact CD2-CD 4.28Å; Y123-K132 HydrophobicContact CD2-CG 4.34Å; Y123-K132 HydrophobicContact CE2-CB 4.39Å; Y123-K132 HydrophobicContact CE2-CD 4.4Å; Y123-K132 HydrophobicContact CE2-CG 4.2Å; Y123-K132 WeakPolarHBondContact O-CD 3.48Å; Y123-K132 PolarHBondContact O-NZ 3.03Å; C126-K132 PolarHBondContact O-NZ 3.35Å; D128-K132 WeakPolarHBondContact O-CG 3.45Å; D128-K132 PolarHBondContact O-N 3.28Å; K132-L136 WeakPolarHBondContact O-CB 3.43Å; K132-L136 PolarHBondContact O-N 2.72Å
133N84.4Confident82.3Confident79 Ų7953 Ų5342%0.42230%0.296SS..Hα-helixtrans-67.1-40.8173.7-71.1-4.5000111.6L129 A131 L136 G137L129-N133 WeakPolarHBondContact O-CB 3.48Å; L129-N133 PolarHBondContact O-N 2.77Å; L129-N133 PolarHBondContact O-ND2 2.98Å; L129-N133 PolarHBondContact O-OD1 2.89Å; A131-N133 VanDerWaalsContact C-N 3.34Å; A131-N133 PolarHBondContact O-N 3.19Å; N133-L136 PolarHBondContact O-N 2.88Å; N133-G137 PolarHBondContact O-N 3.28Å
134V85.4Confident82.9Confident28 Ų2853.3 Ų53.317%0.1731%0.307CS..Hα-helixtrans-66.2-45.2175.9168.80000111.2W32 I35 V39 T130 A131 L136 G137 M138W32-V134 HydrophobicContact CZ3-CG1 4.41Å; I35-V134 HydrophobicContact CG2-CG1 3.93Å; I35-V134 HydrophobicContact CG2-CG2 4.43Å; V39-V134 HydrophobicContact CG2-CG1 4.3Å; V39-V134 HydrophobicContact CG2-CG2 4.1Å; T130-V134 WeakPolarHBondContact O-CG2 3.26Å; T130-V134 PolarHBondContact O-N 3.41Å; T130-V134 VanDerWaalsContact O-N 3.1Å; A131-V134 PolarHBondContact O-N 2.92Å; V134-L136 VanDerWaalsContact C-N 3.34Å; V134-L136 PolarHBondContact O-N 2.63Å; V134-G137 PolarHBondContact O-N 3.41Å; V134-M138 WeakPolarHBondContact O-CB 3.39Å; V134-M138 PolarHBondContact O-N 3.35Å
135T83.6Confident83.4Confident8 Ų847.6 Ų47.65%0.04927%0.271CS..Hα-helixtrans-62.3-39.2176.1-59.70000112.2L55 W118 A131 M138 V139L55-T135 HydrophobicContact CD1-CG2 4.23Å; L55-T135 WeakPolarHBondContact CD1-OG1 3.45Å; W118-T135 HydrophobicContact CE3-CG2 4.25Å; W118-T135 HydrophobicContact CZ3-CG2 4.34Å; A131-T135 PolarHBondContact O-N 2.88Å; A131-T135 PolarHBondContact O-OG1 2.88Å; T135-M138 HydrophobicContact CG2-CE 4.45Å; T135-M138 PolarHBondContact O-N 3.45Å; T135-V139 WeakPolarHBondContact O-CG2 3.4Å; T135-V139 PolarHBondContact O-N 2.84Å
136L87.1Confident84.1Confident64 Ų6444.6 Ų44.634%0.33525%0.25SC..Hα-helixtrans-61.6-50.6173.417963.4000111.6L119 Y123 K132 N133 V134 M138 V139 V140L119-L136 HydrophobicContact CD1-CD1 4.06Å; L119-L136 HydrophobicContact CD2-CB 4.29Å; L119-L136 HydrophobicContact CD2-CD1 4.45Å; Y123-L136 HydrophobicContact CE2-CB 4.45Å; Y123-L136 HydrophobicContact CE2-CD2 4.05Å; K132-L136 WeakPolarHBondContact O-CB 3.43Å; K132-L136 PolarHBondContact O-N 2.72Å; N133-L136 PolarHBondContact O-N 2.88Å; V134-L136 VanDerWaalsContact C-N 3.34Å; V134-L136 PolarHBondContact O-N 2.63Å; L136-M138 VanDerWaalsContact C-N 3.32Å; L136-M138 PolarHBondContact O-N 3.32Å; L136-V139 PolarHBondContact O-N 3.42Å; L136-V140 HydrophobicContact CD1-CG2 4.43Å; L136-V140 WeakPolarHBondContact O-CG2 3.41Å; L136-V140 PolarHBondContact O-N 3.41Å
137G87.2Confident84.6Confident29 Ų2949.6 Ų49.630%0.29928%0.276SS..Hα-helixtrans-61.4-38.6178.200000113.2W32 N133 V134 V140 C141W32-G137 VanDerWaalsContact CH2-C 3.49Å; N133-G137 PolarHBondContact O-N 3.28Å; V134-G137 PolarHBondContact O-N 3.41Å; G137-V140 PolarHBondContact O-N 3.23Å; G137-C141 VanDerWaalsContact O-CB 3.3Å; G137-C141 WeakPolarHBondContact O-CB 3.39Å; G137-C141 PolarHBondContact O-N 3.05Å
138M87.4Confident85.1Confident4 Ų446 Ų462%0.0226%0.261CS..Hα-helixtrans-63.7-46.8176.6-176.2-173.983.800111.9W32 L36 Y62 V134 T135 L136 C141 N142W32-M138 HydrophobicContact CE3-CB 4.06Å; W32-M138 HydrophobicContact CE3-CG 4.3Å; W32-M138 HydrophobicContact CH2-CB 4.37Å; W32-M138 HydrophobicContact CZ3-CB 3.87Å; L36-M138 HydrophobicContact CD1-SD 4.32Å; L36-M138 HydrophobicContact CD2-SD 4.08Å; Y62-M138 HydrophobicContact CD1-CE 3.78Å; Y62-M138 HydrophobicContact CD1-CG 4.03Å; Y62-M138 HydrophobicContact CD1-SD 3.3Å; Y62-M138 WeakPolarHBondContact CD1-SD 3.43Å; Y62-M138 HydrophobicContact CE1-CE 4.15Å; Y62-M138 HydrophobicContact CE1-CG 3.56Å; Y62-M138 HydrophobicContact CE1-SD 3.51Å; Y62-M138 VanDerWaalsContact CE1-SD 3.51Å; Y62-M138 HydrophobicContact CG-CE 3.98Å; Y62-M138 HydrophobicContact CG-SD 4.11Å; V134-M138 WeakPolarHBondContact O-CB 3.39Å; V134-M138 PolarHBondContact O-N 3.35Å; T135-M138 HydrophobicContact CG2-CE 4.45Å; T135-M138 PolarHBondContact O-N 3.45Å; L136-M138 VanDerWaalsContact C-N 3.32Å; L136-M138 PolarHBondContact O-N 3.32Å; M138-C141 PolarHBondContact O-N 2.75Å; M138-N142 WeakPolarHBondContact O-CB 3.28Å; M138-N142 PolarHBondContact O-N 2.9Å
139V89.2Confident85.6Confident10 Ų1046 Ų466%0.06126%0.262CS..Hα-helixtrans-63.7-45.2176.2169.90000110.7I116 L119 T135 L136 C141 N142 W143I116-V139 HydrophobicContact CG1-CG1 3.89Å; L119-V139 HydrophobicContact CD1-CB 4.09Å; L119-V139 HydrophobicContact CD1-CG1 4.17Å; L119-V139 HydrophobicContact CD1-CG2 4.03Å; T135-V139 WeakPolarHBondContact O-CG2 3.4Å; T135-V139 PolarHBondContact O-N 2.84Å; L136-V139 PolarHBondContact O-N 3.42Å; V139-C141 PolarHBondContact O-N 3Å; V139-N142 PolarHBondContact O-N 2.84Å; V139-W143 VanDerWaalsContact O-CD1 3.29Å; V139-W143 PolarHBondContact O-N 2.83Å
140V89.6Confident85.8Confident85 Ų8544 Ų4452%0.51526%0.256SS..Hα-helixtrans-60.4-46.1176.51710000111.3L136 G137 N142 W143 V144L136-V140 HydrophobicContact CD1-CG2 4.43Å; L136-V140 WeakPolarHBondContact O-CG2 3.41Å; L136-V140 PolarHBondContact O-N 3.41Å; G137-V140 PolarHBondContact O-N 3.23Å; V140-N142 PolarHBondContact O-N 2.98Å; V140-W143 PolarHBondContact O-N 2.9Å; V140-V144 WeakPolarHBondContact O-CG2 3.36Å; V140-V144 PolarHBondContact O-N 2.7Å
141C89.9Confident85.8Confident30 Ų3044.1 Ų44.120%0.20325%0.253CS..Hα-helixtrans-63.5-41.4178.9-169.10000112.1W32 G137 M138 V139 V144 V145W32-C141 HydrophobicContact CZ2-CB 3.72Å; W32-C141 PolarHBondContact NE1-SG 2.71Å; G137-C141 VanDerWaalsContact O-CB 3.3Å; G137-C141 WeakPolarHBondContact O-CB 3.39Å; G137-C141 PolarHBondContact O-N 3.05Å; M138-C141 PolarHBondContact O-N 2.75Å; V139-C141 PolarHBondContact O-N 3Å; C141-V144 PolarHBondContact O-N 3.19Å; C141-V145 WeakPolarHBondContact O-CG2 3.46Å; C141-V145 PolarHBondContact O-N 2.64Å
142N89.4Confident85.9Confident6 Ų647.9 Ų47.93%0.03228%0.275CS..Hα-helixtrans-60.8-47.1176.1-175.3-40000111.2Y62 E108 M138 V139 V140 V144 V145 I146Y62-N142 WeakPolarHBondContact CE2-ND2 3.47Å; Y62-N142 PolarHBondContact OH-ND2 3.35Å; E108-N142 WeakPolarHBondContact CG-ND2 3.49Å; M138-N142 WeakPolarHBondContact O-CB 3.28Å; M138-N142 PolarHBondContact O-N 2.9Å; V139-N142 PolarHBondContact O-N 2.84Å; V140-N142 PolarHBondContact O-N 2.98Å; N142-V144 VanDerWaalsContact C-N 3.31Å; N142-V144 PolarHBondContact O-N 2.78Å; N142-V145 WeakPolarHBondContact O-CA 3.39Å; N142-V145 WeakPolarHBondContact O-CB 3.01Å; N142-V145 PolarHBondContact O-N 3.32Å; N142-I146 WeakPolarHBondContact O-CG1 3.47Å; N142-I146 PolarHBondContact O-N 3.08Å; N142-I146 WeakPolarHBondContact OD1-CD1 3.44Å; N142-I146 WeakPolarHBondContact OD1-CG1 3.43Å
143W89.8Confident85.9Confident88 Ų8849.6 Ų49.633%0.33329%0.289SS..Hα-helixtrans-61.7-35.2176.3-83.998.5000113.5F109 I113 I116 V139 V140 L147F109-W143 HydrophobicContact CD2-CH2 4.2Å; F109-W143 AromaticContact CE2-CH2 3.57Å; F109-W143 HydrophobicContact CE2-CH2 3.57Å; F109-W143 HydrophobicContact CE2-CZ2 4.42Å; F109-W143 AromaticContact CE2-CZ3 3.97Å; F109-W143 HydrophobicContact CE2-CZ3 3.97Å; F109-W143 HydrophobicContact CZ-CH2 4.34Å; I113-W143 HydrophobicContact CG1-CZ2 4.19Å; I116-W143 HydrophobicContact CD1-CZ2 4.01Å; I116-W143 VanDerWaalsContact CD1-NE1 3.33Å; V139-W143 VanDerWaalsContact O-CD1 3.29Å; V139-W143 PolarHBondContact O-N 2.83Å; V140-W143 PolarHBondContact O-N 2.9Å; W143-L147 WeakPolarHBondContact O-CB 3.4Å; W143-L147 PolarHBondContact O-N 3.24Å
144V88.9Confident85.5Confident90 Ų9051.4 Ų51.455%0.54530%0.297SS..Hα-helixtrans-65.9-41.4171.7171.90000111.5V140 C141 N142 L147 S148V140-V144 WeakPolarHBondContact O-CG2 3.36Å; V140-V144 PolarHBondContact O-N 2.7Å; C141-V144 PolarHBondContact O-N 3.19Å; N142-V144 VanDerWaalsContact C-N 3.31Å; N142-V144 PolarHBondContact O-N 2.78Å; V144-L147 PolarHBondContact O-N 3Å; V144-S148 WeakPolarHBondContact O-CB 3.44Å; V144-S148 PolarHBondContact O-N 3.44Å; V144-S148 PolarHBondContact O-OG 3.37Å
145V88.4Confident84.6Confident8 Ų851.2 Ų51.25%0.04830%0.297CS..Hα-helixtrans-62.7-51.4175170.20000110.6L25 L28 C141 N142 L147 S148 V149L25-V145 HydrophobicContact CD2-CG1 3.79Å; L28-V145 HydrophobicContact CD1-CG2 4.02Å; L28-V145 HydrophobicContact CD2-CG2 4.02Å; C141-V145 WeakPolarHBondContact O-CG2 3.46Å; C141-V145 PolarHBondContact O-N 2.64Å; N142-V145 WeakPolarHBondContact O-CA 3.39Å; N142-V145 WeakPolarHBondContact O-CB 3.01Å; N142-V145 PolarHBondContact O-N 3.32Å; V145-L147 VanDerWaalsContact C-N 3.32Å; V145-L147 PolarHBondContact O-N 2.99Å; V145-S148 PolarHBondContact O-N 3.03Å; V145-S148 VanDerWaalsContact O-N 3.16Å; V145-S148 PolarHBondContact O-OG 2.93Å; V145-V149 HydrophobicContact CG1-CG2 4.49Å; V145-V149 WeakPolarHBondContact O-CG2 3.28Å; V145-V149 PolarHBondContact O-N 3.27Å
146I87.7Confident84Confident14 Ų1452.7 Ų52.77%0.07231%0.306CS..Hα-helixtrans-56.6-45.7177.4-69.3177.9000111.1L105 F109 N142 S148 V149 C150L105-I146 HydrophobicContact CD1-CG1 4.22Å; F109-I146 HydrophobicContact CB-CD1 4.1Å; F109-I146 HydrophobicContact CD2-CD1 4.13Å; F109-I146 HydrophobicContact CD2-CG2 4.36Å; N142-I146 WeakPolarHBondContact O-CG1 3.47Å; N142-I146 PolarHBondContact O-N 3.08Å; N142-I146 WeakPolarHBondContact OD1-CD1 3.44Å; N142-I146 WeakPolarHBondContact OD1-CG1 3.43Å; I146-S148 PolarHBondContact O-N 3.49Å; I146-V149 PolarHBondContact O-N 3.5Å; I146-C150 PolarHBondContact O-N 3.27Å; I146-C150 PolarHBondContact O-SG 3.3Å; I146-C150 VanDerWaalsContact O-SG 3.38Å
147L85.7Confident83.5Confident106 Ų10652.5 Ų52.556%0.55530%0.303SS*.Hα-helixtrans-64.1-40178.8-176.5144000112.2W143 V144 V145 C150 I151W143-L147 WeakPolarHBondContact O-CB 3.4Å; W143-L147 PolarHBondContact O-N 3.24Å; V144-L147 PolarHBondContact O-N 3Å; V145-L147 VanDerWaalsContact C-N 3.32Å; V145-L147 PolarHBondContact O-N 2.99Å; L147-C150 PolarHBondContact O-N 2.62Å; L147-I151 HydrophobicContact CD2-CD1 3.6Å; L147-I151 HydrophobicContact CD2-CG1 4.48Å; L147-I151 HydrophobicContact CG-CD1 4.42Å; L147-I151 WeakPolarHBondContact O-CG1 3.36Å; L147-I151 PolarHBondContact O-N 2.85Å
148S85Confident82.6Confident53 Ų5351.5 Ų51.537%0.37129%0.291SS..Hα-helixtrans-68.2-34.9175.171.60000112.9V144 V145 I146 I151 T152V144-S148 WeakPolarHBondContact O-CB 3.44Å; V144-S148 PolarHBondContact O-N 3.44Å; V144-S148 PolarHBondContact O-OG 3.37Å; V145-S148 PolarHBondContact O-N 3.03Å; V145-S148 VanDerWaalsContact O-N 3.16Å; V145-S148 PolarHBondContact O-OG 2.93Å; I146-S148 PolarHBondContact O-N 3.49Å; S148-I151 PolarHBondContact O-N 3.44Å; S148-T152 WeakPolarHBondContact O-CB 3.43Å; S148-T152 WeakPolarHBondContact O-CG2 3.34Å; S148-T152 PolarHBondContact O-N 2.87Å; S148-T152 PolarHBondContact O-OG1 3.29Å
149V85.7Confident81.5Confident35 Ų3553.3 Ų53.321%0.21230%0.303CS..Hα-helixtrans-65.2-41.8171.2173.10000110.8L105 V145 I146 T152 V153L105-V149 HydrophobicContact CD2-CG1 3.83Å; V145-V149 HydrophobicContact CG1-CG2 4.49Å; V145-V149 WeakPolarHBondContact O-CG2 3.28Å; V145-V149 PolarHBondContact O-N 3.27Å; I146-V149 PolarHBondContact O-N 3.5Å; V149-T152 WeakPolarHBondContact CA-OG1 3.25Å; V149-T152 PolarHBondContact O-OG1 3.07Å; V149-T152 VanDerWaalsContact O-OG1 3.1Å; V149-V153 HydrophobicContact CG1-CG2 4.35Å; V149-V153 VanDerWaalsContact O-CB 3.29Å; V149-V153 WeakPolarHBondContact O-CB 3.35Å; V149-V153 WeakPolarHBondContact O-CG2 3.01Å; V149-V153 PolarHBondContact O-N 3.5Å
150C82.8Confident80.2Confident69 Ų6953.4 Ų53.447%0.46630%0.303SS..Hα-helixtrans-61.6-45.1174.2-72.10000112.5I146 L147 L154I146-C150 PolarHBondContact O-N 3.27Å; I146-C150 PolarHBondContact O-SG 3.3Å; I146-C150 VanDerWaalsContact O-SG 3.38Å; L147-C150 PolarHBondContact O-N 2.62Å; C150-L154 VanDerWaalsContact O-CG 3.28Å; C150-L154 WeakPolarHBondContact O-CG 3.44Å; C150-L154 PolarHBondContact O-N 2.9Å
151I77.6Confident79.1Confident89 Ų8949.3 Ų49.346%0.45628%0.279SS..Hα-helixtrans-63.5-49.7177.6-69.3171.9000111L147 S148 V153 L154 C155L147-I151 HydrophobicContact CD2-CD1 3.6Å; L147-I151 HydrophobicContact CD2-CG1 4.48Å; L147-I151 HydrophobicContact CG-CD1 4.42Å; L147-I151 WeakPolarHBondContact O-CG1 3.36Å; L147-I151 PolarHBondContact O-N 2.85Å; S148-I151 PolarHBondContact O-N 3.44Å; I151-V153 VanDerWaalsContact C-N 3.34Å; I151-V153 PolarHBondContact O-N 3.14Å; I151-L154 WeakPolarHBondContact O-CB 3.32Å; I151-L154 PolarHBondContact O-N 3.28Å; I151-L154 VanDerWaalsContact O-N 3.08Å; I151-C155 PolarHBondContact O-N 3.45Å; I151-C155 PolarHBondContact O-SG 3.22Å; I151-C155 VanDerWaalsContact O-SG 3.37Å
152T78.7Confident78Confident79 Ų7954.5 Ų54.549%0.48529%0.294SS..Hα-helixtrans-62.7-39.418050.40000112.1S148 V149 L154 C155 V156S148-T152 WeakPolarHBondContact O-CB 3.43Å; S148-T152 WeakPolarHBondContact O-CG2 3.34Å; S148-T152 PolarHBondContact O-N 2.87Å; S148-T152 PolarHBondContact O-OG1 3.29Å; V149-T152 WeakPolarHBondContact CA-OG1 3.25Å; V149-T152 PolarHBondContact O-OG1 3.07Å; V149-T152 VanDerWaalsContact O-OG1 3.1Å; T152-L154 PolarHBondContact O-N 2.84Å; T152-C155 PolarHBondContact O-N 3.07Å; T152-V156 WeakPolarHBondContact O-CB 3.33Å; T152-V156 VanDerWaalsContact O-CG2 3.25Å; T152-V156 WeakPolarHBondContact O-CG2 3.35Å; T152-V156 PolarHBondContact O-N 3.36Å
153V81.1Confident76.8Confident68 Ų6856.5 Ų56.541%0.41231%0.306SS..Hα-helixtrans-59.6-43.9171.4165.90000111.5W11 V149 I151 V156 F157W11-V153 HydrophobicContact CH2-CG1 4.23Å; W11-V153 HydrophobicContact CZ3-CG1 4.1Å; V149-V153 HydrophobicContact CG1-CG2 4.35Å; V149-V153 VanDerWaalsContact O-CB 3.29Å; V149-V153 WeakPolarHBondContact O-CB 3.35Å; V149-V153 WeakPolarHBondContact O-CG2 3.01Å; V149-V153 PolarHBondContact O-N 3.5Å; I151-V153 VanDerWaalsContact C-N 3.34Å; I151-V153 PolarHBondContact O-N 3.14Å; V153-V156 PolarHBondContact O-N 3.09Å; V153-F157 WeakPolarHBondContact O-CB 3.46Å; V153-F157 PolarHBondContact O-N 3.29Å
154L74.7Confident75.6Confident116 Ų11653.7 Ų53.761%0.60730%0.297SS*.Hα-helixtrans-63.7-41.9177.8-73.8167.5000112.6C150 I151 T152C150-L154 VanDerWaalsContact O-CG 3.28Å; C150-L154 WeakPolarHBondContact O-CG 3.44Å; C150-L154 PolarHBondContact O-N 2.9Å; I151-L154 WeakPolarHBondContact O-CB 3.32Å; I151-L154 PolarHBondContact O-N 3.28Å; I151-L154 VanDerWaalsContact O-N 3.08Å; T152-L154 PolarHBondContact O-N 2.84Å
155C67.6Low74.5Confident25 Ų2551.5 Ų51.517%0.16928%0.283CS..Hα-helixtrans-65-45.9176.4-65.90000112I151 T152 R197 F201I151-C155 PolarHBondContact O-N 3.45Å; I151-C155 PolarHBondContact O-SG 3.22Å; I151-C155 VanDerWaalsContact O-SG 3.37Å; T152-C155 PolarHBondContact O-N 3.07Å; C155-R197 PolarHBondContact O-NE 3.44Å; C155-R197 PolarHBondContact O-NH2 3.16Å; C155-F201 HydrophobicContact CB-CE2 4.11Å
156V71.7Confident73.5Confident39 Ų3958.1 Ų58.124%0.23631%0.311CS..Hα-helixtrans-79-21-175.2175.30000113.1W11 S12 V13 T152 V153 D158 R197W11-V156 HydrophobicContact CB-CG1 4.37Å; W11-V156 HydrophobicContact CE3-CG1 4.2Å; S12-V156 PolarHBondContact N-O 2.96Å; S12-V156 PolarHBondContact OG-O 3.34Å; S12-V156 VanDerWaalsContact OG-O 3.11Å; V13-V156 HydrophobicContact CB-CG1 3.58Å; V13-V156 HydrophobicContact CG2-CB 4.29Å; V13-V156 HydrophobicContact CG2-CG1 3.46Å; V13-V156 VanDerWaalsContact CG2-CG1 3.46Å; V13-V156 HydrophobicContact CG2-CG2 3.74Å; T152-V156 WeakPolarHBondContact O-CB 3.33Å; T152-V156 VanDerWaalsContact O-CG2 3.25Å; T152-V156 WeakPolarHBondContact O-CG2 3.35Å; T152-V156 PolarHBondContact O-N 3.36Å; V153-V156 PolarHBondContact O-N 3.09Å; V156-D158 PolarHBondContact O-N 2.99Å; V156-R197 PolarHBondContact O-NH2 2.89Å
157F75.8Confident72.3Confident59 Ų5958.7 Ų58.726%0.25931%0.314SS..  trans-61.9120.2178.9-179.6-85000112.2R9 W11 V153 P159 R197R9-F157 VanDerWaalsContact CZ-CZ 3.44Å; W11-F157 HydrophobicContact CE3-CB 4.23Å; W11-F157 AromaticContact CH2-CD2 3.79Å; W11-F157 HydrophobicContact CH2-CD2 3.79Å; W11-F157 HydrophobicContact CZ2-CD2 4.4Å; W11-F157 HydrophobicContact CZ3-CB 3.82Å; W11-F157 AromaticContact CZ3-CD2 3.86Å; W11-F157 HydrophobicContact CZ3-CD2 3.86Å; W11-F157 HydrophobicContact CZ3-CG 4.3Å; V153-F157 WeakPolarHBondContact O-CB 3.46Å; V153-F157 PolarHBondContact O-N 3.29Å; F157-P159 HydrophobicContact CE1-CB 4.33Å; F157-R197 PolarHBondContact O-NH2 3.06Å; F157-R197 VanDerWaalsContact O-NH2 3.16Å
158D68.4Low71.2Confident9 Ų959.5 Ų59.55%0.04831%0.31CS..  trans-96.7112.7174.71755.3000109.9R9 V156 T160 G161R9-D158 WeakPolarHBondContact CD-O 3.34Å; R9-D158 PolarHBondContact NE-O 3.19Å; V156-D158 PolarHBondContact O-N 2.99Å; D158-T160 VanDerWaalsContact CG-OG1 3.27Å; D158-T160 PolarHBondContact O-N 2.72Å; D158-T160 WeakPolarHBondContact OD1-CA 3.23Å; D158-T160 WeakPolarHBondContact OD1-CB 3.24Å; D158-T160 PolarHBondContact OD1-N 2.72Å; D158-T160 PolarHBondContact OD1-OG1 2.83Å; D158-T160 PolarHBondContact OD2-OG1 3.21Å; D158-T160 VanDerWaalsContact OD2-OG1 3.11Å; D158-G161 PolarHBondContact O-N 2.92Å; D158-G161 PolarHBondContact OD1-N 2.85Å; D158-G161 PolarHBondContact OD2-N 2.66Å
159P64.7Low70Confident42 Ų4259.8 Ų59.827%0.27332%0.316SS..THydrogen-bonded Turntrans-61.8-33177.227.1-32.9000111.8R9 F157 G161 S193R9-P159 PolarHBondContact NH2-O 2.87Å; F157-P159 HydrophobicContact CE1-CB 4.33Å; P159-G161 VanDerWaalsContact C-N 3.34Å; P159-G161 PolarHBondContact O-N 3.09Å; P159-S193 WeakPolarHBondContact CD-OG 3.5Å
160T61.6Low68.6Low11 Ų1161.1 Ų61.17%0.06732%0.324CS..THydrogen-bonded Turntrans-76.5-18.1-178.279.30000114D158 R162 T163 F164 G189D158-T160 VanDerWaalsContact CG-OG1 3.27Å; D158-T160 PolarHBondContact O-N 2.72Å; D158-T160 WeakPolarHBondContact OD1-CA 3.23Å; D158-T160 WeakPolarHBondContact OD1-CB 3.24Å; D158-T160 PolarHBondContact OD1-N 2.72Å; D158-T160 PolarHBondContact OD1-OG1 2.83Å; D158-T160 PolarHBondContact OD2-OG1 3.21Å; D158-T160 VanDerWaalsContact OD2-OG1 3.11Å; T160-R162 CarbonylContact O-C 3.56Å; T160-R162 PolarHBondContact O-N 3.11Å; T160-T163 WeakPolarHBondContact O-CA 3.36Å; T160-T163 VanDerWaalsContact O-CB 3.31Å; T160-T163 WeakPolarHBondContact O-CB 3.22Å; T160-T163 PolarHBondContact O-N 2.93Å; T160-F164 PolarHBondContact O-N 3.49Å; T160-F164 VanDerWaalsContact O-N 3.08Å; T160-G189 VanDerWaalsContact CG2-CA 3.44Å; T160-G189 WeakPolarHBondContact CG2-O 3.38Å
161G65.6Low67.2Low0 Ų065.2 Ų65.20%033%0.334CS..Hα-helixtrans-60.6-15.6-165.800000115.7R10 D158 P159 V165R10-G161 PolarHBondContact N-O 3.01Å; R10-G161 WeakPolarHBondContact O-CA 3.4Å; D158-G161 PolarHBondContact O-N 2.92Å; D158-G161 PolarHBondContact OD1-N 2.85Å; D158-G161 PolarHBondContact OD2-N 2.66Å; P159-G161 VanDerWaalsContact C-N 3.34Å; P159-G161 PolarHBondContact O-N 3.09Å; G161-V165 VanDerWaalsContact O-CG2 3.32Å; G161-V165 WeakPolarHBondContact O-CG2 3.35Å; G161-V165 PolarHBondContact O-N 2.9Å
162R68.1Low66Low139 Ų13972.1 Ų72.153%0.52535%0.354SS..Hα-helixtrans-76.9-38.7168.2-72.4-175.3170.4172.1-1.6112.7R9 T160 K166R9-R162 HydrophobicContact CB-CG 3.85Å; R9-R162 HydrophobicContact CG-CG 4.38Å; T160-R162 CarbonylContact O-C 3.56Å; T160-R162 PolarHBondContact O-N 3.11Å; R162-K166 WeakPolarHBondContact O-CG 3.31Å; R162-K166 PolarHBondContact O-N 3.12Å; R162-K166 VanDerWaalsContact O-N 3.14Å
163T63.7Low64.6Low47 Ų4779 Ų7929%0.28837%0.371SS..Hα-helixtrans-66.7-40.5173.9-48.30000110.5T160 K166 L167 L182 L186T160-T163 WeakPolarHBondContact O-CA 3.36Å; T160-T163 VanDerWaalsContact O-CB 3.31Å; T160-T163 WeakPolarHBondContact O-CB 3.22Å; T160-T163 PolarHBondContact O-N 2.93Å; T163-K166 WeakPolarHBondContact O-CB 3.32Å; T163-K166 PolarHBondContact O-N 3.47Å; T163-L167 PolarHBondContact O-N 3.36Å; T163-L182 HydrophobicContact CG2-CD1 3.94Å; T163-L186 HydrophobicContact CG2-CD1 4.11Å; T163-L186 HydrophobicContact CG2-CG 3.95Å
164F64.5Low62.8Low30 Ų3082.1 Ų82.113%0.13238%0.381CS..Hα-helixtrans-58.3-49.2174.7-175.4-95.4000112.5R10 T160 K166 L167 R168 L186 D230R10-F164 HydrophobicContact CB-CD1 4.11Å; R10-F164 VanDerWaalsContact CD-CD1 3.48Å; R10-F164 HydrophobicContact CG-CD1 4.42Å; T160-F164 PolarHBondContact O-N 3.49Å; T160-F164 VanDerWaalsContact O-N 3.08Å; F164-K166 VanDerWaalsContact C-N 3.31Å; F164-K166 PolarHBondContact O-N 3.07Å; F164-L167 PolarHBondContact O-N 2.89Å; F164-R168 WeakPolarHBondContact O-CB 3.28Å; F164-R168 PolarHBondContact O-N 2.98Å; F164-L186 HydrophobicContact CB-CD2 3.95Å; F164-L186 HydrophobicContact CD2-CD2 4.35Å; F164-D230 WeakPolarHBondContact CZ-OD1 3.31Å
165V66.3Low61.6Low43 Ų4388.3 Ų88.326%0.26140%0.396SS..Hα-helixtrans-61.7-39.2177.5171.40000111.4V5 G161 R168 A169V5-V165 HydrophobicContact CG1-CG2 3.99Å; V5-V165 HydrophobicContact CG2-CG2 4.35Å; G161-V165 VanDerWaalsContact O-CG2 3.32Å; G161-V165 WeakPolarHBondContact O-CG2 3.35Å; G161-V165 PolarHBondContact O-N 2.9Å; V165-R168 PolarHBondContact O-N 2.9Å; V165-A169 WeakPolarHBondContact O-CB 3.45Å; V165-A169 PolarHBondContact O-N 3.48Å
166K67.6Low60.6Low147 Ų14792 Ų9264%0.63941%0.414SS*.Hα-helixtrans-62.2-47173-74.5176.4176.2-174.20112.4R162 T163 F164 A169 T170R162-K166 WeakPolarHBondContact O-CG 3.31Å; R162-K166 PolarHBondContact O-N 3.12Å; R162-K166 VanDerWaalsContact O-N 3.14Å; T163-K166 WeakPolarHBondContact O-CB 3.32Å; T163-K166 PolarHBondContact O-N 3.47Å; F164-K166 VanDerWaalsContact C-N 3.31Å; F164-K166 PolarHBondContact O-N 3.07Å; K166-A169 PolarHBondContact O-N 2.92Å; K166-T170 PolarHBondContact O-N 3.49Å; K166-T170 PolarHBondContact O-OG1 3.44Å
167L61.5Low59.4Low26 Ų2696.8 Ų96.814%0.13644%0.438CS..Hα-helixtrans-65.1-37.8177.9179.5138.6000112T163 F164 A169 T170 K171 L182 R183 L186T163-L167 PolarHBondContact O-N 3.36Å; F164-L167 PolarHBondContact O-N 2.89Å; L167-A169 VanDerWaalsContact C-N 3.32Å; L167-A169 PolarHBondContact O-N 3.41Å; L167-T170 WeakPolarHBondContact CA-OG1 2.91Å; L167-T170 PolarHBondContact O-N 3.46Å; L167-T170 PolarHBondContact O-OG1 3.19Å; L167-K171 VanDerWaalsContact O-CB 3.23Å; L167-K171 WeakPolarHBondContact O-CB 2.91Å; L167-K171 PolarHBondContact O-N 3.27Å; L167-L182 HydrophobicContact CB-CD2 3.89Å; L167-L182 HydrophobicContact CB-CG 4.21Å; L167-L182 HydrophobicContact CD1-CB 4.04Å; L167-L182 HydrophobicContact CD1-CD2 4.15Å; L167-L182 HydrophobicContact CD1-CG 3.89Å; L167-L182 HydrophobicContact CG-CD2 4.33Å; L167-R183 HydrophobicContact CD1-CB 4.29Å; L167-L186 HydrophobicContact CB-CD1 3.75Å; L167-L186 HydrophobicContact CD1-CD1 3.9Å; L167-L186 HydrophobicContact CD2-CD1 4.4Å; L167-L186 HydrophobicContact CG-CD1 4.2Å
168R61.9Low58Low124 Ų124104.9 Ų104.947%0.46847%0.467SS..Hα-helixtrans-65.9-34.7175.2-168.6168.5178.5140.3-7.4112F164 V165 R172 D230F164-R168 WeakPolarHBondContact O-CB 3.28Å; F164-R168 PolarHBondContact O-N 2.98Å; V165-R168 PolarHBondContact O-N 2.9Å; R168-R172 PolarHBondContact O-N 3.34Å; R168-D230 IonicContact NH1-OD2 2.83Å; R168-D230 PolarHBondContact NH1-OD2 2.92Å
169A61.5Low57.3Low59 Ų59106.4 Ų106.449%0.48848%0.477SS..Hα-helixtrans-70.4-40.3173.500000112.9V165 K166 L167 R172V165-A169 WeakPolarHBondContact O-CB 3.45Å; V165-A169 PolarHBondContact O-N 3.48Å; K166-A169 PolarHBondContact O-N 2.92Å; L167-A169 VanDerWaalsContact C-N 3.32Å; L167-A169 PolarHBondContact O-N 3.41Å; A169-R172 PolarHBondContact O-N 3.46Å
170T56.1Low56.6Low63 Ų63110.9 Ų110.939%0.38749%0.489SS..Hα-helixtrans-74.6-32.8176.455.80000113K166 L167 R172 R173 Q174K166-T170 PolarHBondContact O-N 3.49Å; K166-T170 PolarHBondContact O-OG1 3.44Å; L167-T170 WeakPolarHBondContact CA-OG1 2.91Å; L167-T170 PolarHBondContact O-N 3.46Å; L167-T170 PolarHBondContact O-OG1 3.19Å; T170-R172 PolarHBondContact O-N 2.73Å; T170-R173 CarbonylContact O-C 3.59Å; T170-R173 WeakPolarHBondContact O-CA 3.49Å; T170-R173 PolarHBondContact O-N 3.25Å; T170-Q174 PolarHBondContact O-N 2.89Å
171K52.1Low56.3Low155 Ų155116.2 Ų116.267%0.67452%0.517SS*.Hα-helixtrans-62.2-26.7173.4-171.6174-177.9177.90112.9L167 R173L167-K171 VanDerWaalsContact O-CB 3.23Å; L167-K171 WeakPolarHBondContact O-CB 2.91Å; L167-K171 PolarHBondContact O-N 3.27Å; K171-R173 VanDerWaalsContact C-N 3.33Å
172R53.5Low55.9Low233 Ų233118.9 Ų118.988%0.87953%0.531SS*.THydrogen-bonded Turntrans-77.6-10.4168.6-86.2-171.7171.5-178.4-2.8114.2R168 A169 T170R168-R172 PolarHBondContact O-N 3.34Å; A169-R172 PolarHBondContact O-N 3.46Å; T170-R172 PolarHBondContact O-N 2.73Å
173R47.8Very low55.3Low225 Ų225116.6 Ų116.685%0.84952%0.523SS*.THydrogen-bonded Turntrans-113.1-27.7-174.9-104.7-177.6174.1-177-2.4115.1T170 K171T170-R173 CarbonylContact O-C 3.59Å; T170-R173 WeakPolarHBondContact O-CA 3.49Å; T170-R173 PolarHBondContact O-N 3.25Å; K171-R173 VanDerWaalsContact C-N 3.33Å
174Q44.3Very low54.9Low132 Ų132119.9 Ų119.962%0.61753%0.534SS*.  trans-158.9136.5179.9-115.9169.3-11.800113.8T170T170-Q174 PolarHBondContact O-N 2.89Å
175R49.1Very low54.6Low247 Ų247126.2 Ų126.293%0.93256%0.557SS**  trans-91.393.4160.6-72.4179.1173.3135.1-8108
176N46.7Very low54.2Low101 Ų101124.5 Ų124.554%0.5455%0.547SS..SBendtrans-156.5153.6-179.8-107.8-25.1000112.3R178 T179N176-R178 PolarHBondContact O-N 3.42Å; N176-T179 PolarHBondContact O-N 2.93Å; N176-T179 PolarHBondContact O-OG1 3.49Å
177L45.9Very low53.6Low141 Ų141119.6 Ų119.674%0.73853%0.526SS*.THydrogen-bonded Turntrans-43.7-33.7-166.2-130.872.4000116.5T179 Y180L177-T179 PolarHBondContact O-N 2.74Å; L177-Y180 PolarHBondContact O-N 2.78Å
178R47.9Very low53.5Low228 Ų228122.1 Ų122.186%0.8654%0.537SS*.Hα-helixtrans-53-22173.4-82.8-177.7170.5167.4-1.9114.3N176 Y180 L182N176-R178 PolarHBondContact O-N 3.42Å; R178-Y180 VanDerWaalsContact C-N 3.32Å; R178-L182 PolarHBondContact O-N 3.18Å
179T52.1Low53.2Low42 Ų42116.7 Ų116.726%0.25852%0.52SS..Hα-helixtrans-66.3-30.217451.70000113.2N176 L177 R183N176-T179 PolarHBondContact O-N 2.93Å; N176-T179 PolarHBondContact O-OG1 3.49Å; L177-T179 PolarHBondContact O-N 2.74Å; T179-R183 VanDerWaalsContact O-CB 3.27Å; T179-R183 WeakPolarHBondContact O-CB 3.15Å; T179-R183 PolarHBondContact O-N 2.97Å
180Y50.6Low52.9Low135 Ų135116.4 Ų116.453%0.52951%0.508SS..Hα-helixtrans-68.5-53.3179.7-75.8-78.6000111.6L177 R178 L182 R183 H184L177-Y180 PolarHBondContact O-N 2.78Å; R178-Y180 VanDerWaalsContact C-N 3.32Å; Y180-L182 PolarHBondContact O-N 2.7Å; Y180-R183 WeakPolarHBondContact O-CA 3.39Å; Y180-R183 WeakPolarHBondContact O-CB 3.35Å; Y180-R183 PolarHBondContact O-N 3.06Å; Y180-H184 PolarHBondContact O-N 3.12Å
181N56.6Low52.8Low124 Ų124113.8 Ų113.866%0.66349%0.494SS*.Hα-helixtrans-60.1-33.8178.1-62.717.2000112.1R183 R185N181-R183 VanDerWaalsContact C-N 3.33Å; N181-R185 WeakPolarHBondContact O-CB 3.36Å; N181-R185 WeakPolarHBondContact O-CG 3.3Å; N181-R185 PolarHBondContact O-N 3.37Å
182L55.7Low53Low55 Ų55110.6 Ų110.629%0.28849%0.487SS..Hα-helixtrans-76.7-19.4175.8-168.263.6000113.2T163 L167 R178 Y180T163-L182 HydrophobicContact CG2-CD1 3.94Å; L167-L182 HydrophobicContact CB-CD2 3.89Å; L167-L182 HydrophobicContact CB-CG 4.21Å; L167-L182 HydrophobicContact CD1-CB 4.04Å; L167-L182 HydrophobicContact CD1-CD2 4.15Å; L167-L182 HydrophobicContact CD1-CG 3.89Å; L167-L182 HydrophobicContact CG-CD2 4.33Å; R178-L182 PolarHBondContact O-N 3.18Å; Y180-L182 PolarHBondContact O-N 2.7Å
183R56.1Low53.1Low92 Ų9299.6 Ų99.635%0.34745%0.446SS..Hα-helixtrans-81.3-45.1174.4-162.3-175.1-174.6165.60.4111.1L167 T179 Y180 N181 R185 L186 E187 D228L167-R183 HydrophobicContact CD1-CB 4.29Å; T179-R183 VanDerWaalsContact O-CB 3.27Å; T179-R183 WeakPolarHBondContact O-CB 3.15Å; T179-R183 PolarHBondContact O-N 2.97Å; Y180-R183 WeakPolarHBondContact O-CA 3.39Å; Y180-R183 WeakPolarHBondContact O-CB 3.35Å; Y180-R183 PolarHBondContact O-N 3.06Å; N181-R183 VanDerWaalsContact C-N 3.33Å; R183-R185 VanDerWaalsContact C-N 3.27Å; R183-R185 PolarHBondContact O-N 3.09Å; R183-L186 CarbonylContact O-C 3.37Å; R183-L186 WeakPolarHBondContact O-CA 3.46Å; R183-L186 VanDerWaalsContact O-CB 3.27Å; R183-L186 WeakPolarHBondContact O-CB 3.36Å; R183-L186 PolarHBondContact O-N 3.15Å; R183-E187 WeakPolarHBondContact CG-OE1 3.43Å; R183-E187 IonicContact NE-OE1 3.58Å; R183-E187 PolarHBondContact O-N 2.84Å; R183-D228 IonicContact NH2-OD1 3.3Å; R183-D228 PolarHBondContact NH2-OD1 3.11Å
184H55.8Low53.4Low115 Ų11593.7 Ų93.753%0.53242%0.424SS..Hα-helixtrans-56.2-42.5171.4-160.6-85.2000111.7Y180 L186 E187 E188Y180-H184 PolarHBondContact O-N 3.12Å; H184-L186 PolarHBondContact O-N 2.93Å; H184-E187 VanDerWaalsContact CA-OE2 3.25Å; H184-E187 WeakPolarHBondContact CA-OE2 3.37Å; H184-E187 PolarHBondContact N-OE2 2.92Å; H184-E187 PolarHBondContact O-N 2.86Å; H184-E187 VanDerWaalsContact O-N 3.13Å; H184-E188 IonicContact CE1-OE1 2.78Å; H184-E188 IonicContact CG-OE1 2.7Å; H184-E188 IonicContact ND1-OE1 2.7Å; H184-E188 PolarHBondContact ND1-OE1 3.36Å; H184-E188 WeakPolarHBondContact O-CB 3.23Å; H184-E188 WeakPolarHBondContact O-CG 3.23Å; H184-E188 PolarHBondContact O-N 2.97Å
185R58.3Low53.9Low163 Ų16387.6 Ų87.662%0.61540%0.396SS*.Hα-helixtrans-68.7-9.3174.2-67.1-71.4-109.8-176.1-5.4114.7N181 R183 E188N181-R185 WeakPolarHBondContact O-CB 3.36Å; N181-R185 WeakPolarHBondContact O-CG 3.3Å; N181-R185 PolarHBondContact O-N 3.37Å; R183-R185 VanDerWaalsContact C-N 3.27Å; R183-R185 PolarHBondContact O-N 3.09Å; R185-E188 WeakPolarHBondContact CD-OE2 3.4Å; R185-E188 IonicContact CZ-OE2 3.33Å; R185-E188 IonicContact NE-OE2 3.05Å; R185-E188 IonicContact NH1-OE2 2.69Å; R185-E188 PolarHBondContact NH1-OE2 3.36Å
186L57.1Low54.3Low8 Ų880.9 Ų80.94%0.04237%0.37CS..Hα-helixtrans-97.7-33.9169.9-101156.1000111.5T163 F164 L167 R183 H184 G189 Q190T163-L186 HydrophobicContact CG2-CD1 4.11Å; T163-L186 HydrophobicContact CG2-CG 3.95Å; F164-L186 HydrophobicContact CB-CD2 3.95Å; F164-L186 HydrophobicContact CD2-CD2 4.35Å; L167-L186 HydrophobicContact CB-CD1 3.75Å; L167-L186 HydrophobicContact CD1-CD1 3.9Å; L167-L186 HydrophobicContact CD2-CD1 4.4Å; L167-L186 HydrophobicContact CG-CD1 4.2Å; R183-L186 CarbonylContact O-C 3.37Å; R183-L186 WeakPolarHBondContact O-CA 3.46Å; R183-L186 VanDerWaalsContact O-CB 3.27Å; R183-L186 WeakPolarHBondContact O-CB 3.36Å; R183-L186 PolarHBondContact O-N 3.15Å; H184-L186 PolarHBondContact O-N 2.93Å; L186-G189 CarbonylContact O-C 3.56Å; L186-G189 PolarHBondContact O-N 2.83Å; L186-Q190 WeakPolarHBondContact O-CB 3.32Å; L186-Q190 VanDerWaalsContact O-CG 3.31Å; L186-Q190 WeakPolarHBondContact O-CG 3.37Å; L186-Q190 PolarHBondContact O-N 2.82Å
187E56Low54.8Low44 Ų4477.6 Ų77.621%0.20635%0.35CS..Hα-helixtrans-66.1-51.7172.8-71.8146.2177.400110.3R183 H184 G189 Q190 A191R183-E187 WeakPolarHBondContact CG-OE1 3.43Å; R183-E187 IonicContact NE-OE1 3.58Å; R183-E187 PolarHBondContact O-N 2.84Å; H184-E187 VanDerWaalsContact CA-OE2 3.25Å; H184-E187 WeakPolarHBondContact CA-OE2 3.37Å; H184-E187 PolarHBondContact N-OE2 2.92Å; H184-E187 PolarHBondContact O-N 2.86Å; H184-E187 VanDerWaalsContact O-N 3.13Å; E187-G189 PolarHBondContact O-N 2.9Å; E187-Q190 PolarHBondContact O-N 3.07Å; E187-Q190 VanDerWaalsContact O-N 3.16Å; E187-A191 PolarHBondContact O-N 2.86Å
188E58.1Low55.1Low78 Ų7872.7 Ų72.736%0.36433%0.325SS..Hα-helixtrans-46.7-45.6165.4-75.3166.3-141.100111.7H184 R185 T192H184-E188 IonicContact CE1-OE1 2.78Å; H184-E188 IonicContact CG-OE1 2.7Å; H184-E188 IonicContact ND1-OE1 2.7Å; H184-E188 PolarHBondContact ND1-OE1 3.36Å; H184-E188 WeakPolarHBondContact O-CB 3.23Å; H184-E188 WeakPolarHBondContact O-CG 3.23Å; H184-E188 PolarHBondContact O-N 2.97Å; R185-E188 WeakPolarHBondContact CD-OE2 3.4Å; R185-E188 IonicContact CZ-OE2 3.33Å; R185-E188 IonicContact NE-OE2 3.05Å; R185-E188 IonicContact NH1-OE2 2.69Å; R185-E188 PolarHBondContact NH1-OE2 3.36Å; E188-T192 WeakPolarHBondContact O-CB 3.5Å; E188-T192 WeakPolarHBondContact O-CG2 3.45Å; E188-T192 PolarHBondContact O-N 3.39Å; E188-T192 VanDerWaalsContact O-N 3.07Å; E188-T192 PolarHBondContact O-OG1 2.87Å
189G56.4Low55.2Low11 Ų1165.8 Ų65.811%0.11330%0.301CS..Hα-helixtrans-69.6-40.7-177.200000113T160 L186 E187 T192 S193T160-G189 VanDerWaalsContact CG2-CA 3.44Å; T160-G189 WeakPolarHBondContact CG2-O 3.38Å; L186-G189 CarbonylContact O-C 3.56Å; L186-G189 PolarHBondContact O-N 2.83Å; E187-G189 PolarHBondContact O-N 2.9Å; G189-T192 WeakPolarHBondContact CA-OG1 3.38Å; G189-T192 PolarHBondContact O-OG1 2.91Å; G189-T192 VanDerWaalsContact O-OG1 3.05Å; G189-S193 VanDerWaalsContact O-CB 3.24Å; G189-S193 WeakPolarHBondContact O-CB 3.43Å; G189-S193 PolarHBondContact O-N 3.12Å
190Q55.8Low54.9Low52 Ų5267 Ų6724%0.24331%0.308CS..Hα-helixtrans-73.2-41.8-178.1-78.4178.1-35.400110.3L186 E187 T192 S193 W194L186-Q190 WeakPolarHBondContact O-CB 3.32Å; L186-Q190 VanDerWaalsContact O-CG 3.31Å; L186-Q190 WeakPolarHBondContact O-CG 3.37Å; L186-Q190 PolarHBondContact O-N 2.82Å; E187-Q190 PolarHBondContact O-N 3.07Å; E187-Q190 VanDerWaalsContact O-N 3.16Å; Q190-T192 PolarHBondContact O-N 2.81Å; Q190-S193 WeakPolarHBondContact O-CB 3.44Å; Q190-S193 PolarHBondContact O-N 3.49Å; Q190-W194 VanDerWaalsContact O-CD1 3.27Å; Q190-W194 PolarHBondContact O-N 3.41Å
191A52.9Low54.5Low9 Ų967 Ų677%0.07431%0.311CS..Hα-helixtrans-58.7-47.1172.100000111.4E187 S193 W194 S195 A219E187-A191 PolarHBondContact O-N 2.86Å; A191-S193 PolarHBondContact O-N 2.87Å; A191-W194 PolarHBondContact O-N 3.02Å; A191-S195 VanDerWaalsContact O-CB 3.27Å; A191-S195 WeakPolarHBondContact O-CB 3.43Å; A191-S195 PolarHBondContact O-N 2.81Å; A191-A219 HydrophobicContact CB-CB 4.48Å
192T56.7Low53.9Low87 Ų8763.5 Ų63.553%0.53429%0.292SS..Hα-helixtrans-67.8-30.817650.60000113.7E188 G189 Q190 R196E188-T192 WeakPolarHBondContact O-CB 3.5Å; E188-T192 WeakPolarHBondContact O-CG2 3.45Å; E188-T192 PolarHBondContact O-N 3.39Å; E188-T192 VanDerWaalsContact O-N 3.07Å; E188-T192 PolarHBondContact O-OG1 2.87Å; G189-T192 WeakPolarHBondContact CA-OG1 3.38Å; G189-T192 PolarHBondContact O-OG1 2.91Å; G189-T192 VanDerWaalsContact O-OG1 3.05Å; Q190-T192 PolarHBondContact O-N 2.81Å; T192-R196 WeakPolarHBondContact O-CB 3.45Å; T192-R196 PolarHBondContact O-N 2.89Å
193S55.5Low52.9Low3 Ų365.4 Ų65.42%0.02131%0.309CS..Hα-helixtrans-65.5-46.4173.1-176.80000112.2P159 G189 Q190 A191 R196 R197P159-S193 WeakPolarHBondContact CD-OG 3.5Å; G189-S193 VanDerWaalsContact O-CB 3.24Å; G189-S193 WeakPolarHBondContact O-CB 3.43Å; G189-S193 PolarHBondContact O-N 3.12Å; Q190-S193 WeakPolarHBondContact O-CB 3.44Å; Q190-S193 PolarHBondContact O-N 3.49Å; A191-S193 PolarHBondContact O-N 2.87Å; S193-R196 PolarHBondContact O-N 2.98Å; S193-R197 WeakPolarHBondContact O-CG 3.31Å; S193-R197 PolarHBondContact O-N 2.77Å
194W53.8Low51.8Low100 Ų10067 Ų6738%0.37933%0.333SS..Hα-helixtrans-66.5-47.2175-83.2113.5000112.2Q190 A191 R196 R197 L198 A219 P233Q190-W194 VanDerWaalsContact O-CD1 3.27Å; Q190-W194 PolarHBondContact O-N 3.41Å; A191-W194 PolarHBondContact O-N 3.02Å; W194-R196 VanDerWaalsContact C-N 3.26Å; W194-R196 PolarHBondContact O-N 2.85Å; W194-R197 WeakPolarHBondContact O-CA 3.31Å; W194-R197 WeakPolarHBondContact O-CB 3.01Å; W194-R197 PolarHBondContact O-N 3.17Å; W194-L198 PolarHBondContact O-N 2.83Å; W194-A219 HydrophobicContact CB-CB 3.48Å; W194-A219 VanDerWaalsContact CB-CB 3.48Å; W194-A219 HydrophobicContact CG-CB 4.38Å; W194-P233 HydrophobicContact CH2-CG 4.03Å
195S55.3Low50.9Low5 Ų562.8 Ų62.84%0.03532%0.315CS..Hα-helixtrans-54.7-42.3173.4-176.50000111.1A191 K199A191-S195 VanDerWaalsContact O-CB 3.27Å; A191-S195 WeakPolarHBondContact O-CB 3.43Å; A191-S195 PolarHBondContact O-N 2.81Å; S195-K199 WeakPolarHBondContact O-CB 3.3Å; S195-K199 WeakPolarHBondContact O-CD 3.49Å; S195-K199 WeakPolarHBondContact O-CG 3.17Å; S195-K199 PolarHBondContact O-N 3.17Å; S195-K199 WeakPolarHBondContact OG-CE 3.23Å; S195-K199 PolarHBondContact OG-NZ 2.88Å
196R57.7Low49.8Very low105 Ų10567 Ų6740%0.39633%0.331SS..Hα-helixtrans-68.3-32.2175-166.2-17871.5148.511.6113.3T192 S193 W194 V200T192-R196 WeakPolarHBondContact O-CB 3.45Å; T192-R196 PolarHBondContact O-N 2.89Å; S193-R196 PolarHBondContact O-N 2.98Å; W194-R196 VanDerWaalsContact C-N 3.26Å; W194-R196 PolarHBondContact O-N 2.85Å; R196-V200 WeakPolarHBondContact O-CB 3.19Å; R196-V200 VanDerWaalsContact O-CG2 3.23Å; R196-V200 WeakPolarHBondContact O-CG2 3.34Å; R196-V200 PolarHBondContact O-N 3.15Å
197R57.5Low48.8Very low32 Ų3270.4 Ų70.412%0.12135%0.352CS..Hα-helixtrans-69.9-45.3175.1-78.6171.3176.2155.44.7112S12 C155 V156 F157 S193 W194 K199 V200 F201S12-R197 PolarHBondContact OG-NH1 3.35Å; S12-R197 PolarHBondContact OG-NH2 2.95Å; C155-R197 PolarHBondContact O-NE 3.44Å; C155-R197 PolarHBondContact O-NH2 3.16Å; V156-R197 PolarHBondContact O-NH2 2.89Å; F157-R197 PolarHBondContact O-NH2 3.06Å; F157-R197 VanDerWaalsContact O-NH2 3.16Å; S193-R197 WeakPolarHBondContact O-CG 3.31Å; S193-R197 PolarHBondContact O-N 2.77Å; W194-R197 WeakPolarHBondContact O-CA 3.31Å; W194-R197 WeakPolarHBondContact O-CB 3.01Å; W194-R197 PolarHBondContact O-N 3.17Å; R197-K199 VanDerWaalsContact C-N 3.32Å; R197-K199 PolarHBondContact O-N 3.04Å; R197-V200 PolarHBondContact O-N 2.56Å; R197-F201 PolarHBondContact O-N 3.29Å
198L51.1Low48.2Very low38 Ų3876.8 Ų76.820%0.19938%0.38CS..Hα-helixtrans-55.1-49.8170.6-74.4154.3000109.9W194 V200 F201 L202 Y215W194-L198 PolarHBondContact O-N 2.83Å; L198-V200 PolarHBondContact O-N 2.65Å; L198-V200 VanDerWaalsContact O-N 3.15Å; L198-F201 PolarHBondContact O-N 3.13Å; L198-L202 WeakPolarHBondContact O-CB 3.24Å; L198-L202 WeakPolarHBondContact O-CD1 3.33Å; L198-L202 PolarHBondContact O-N 2.89Å; L198-Y215 HydrophobicContact CB-CD1 4.3Å; L198-Y215 HydrophobicContact CB-CG 4.48Å; L198-Y215 HydrophobicContact CD1-CD1 3.98Å; L198-Y215 HydrophobicContact CD1-CG 4.45Å; L198-Y215 HydrophobicContact CD2-CD1 4.37Å; L198-Y215 HydrophobicContact CG-CD1 4.44Å
199K49.7Very low47.7Very low84 Ų8479.5 Ų79.537%0.36540%0.397SS..Hα-helixtrans-63.7-15.6175.4-70163.3179.7163.20115.4S195 R197 C203 S212S195-K199 WeakPolarHBondContact O-CB 3.3Å; S195-K199 WeakPolarHBondContact O-CD 3.49Å; S195-K199 WeakPolarHBondContact O-CG 3.17Å; S195-K199 PolarHBondContact O-N 3.17Å; S195-K199 WeakPolarHBondContact OG-CE 3.23Å; S195-K199 PolarHBondContact OG-NZ 2.88Å; R197-K199 VanDerWaalsContact C-N 3.32Å; R197-K199 PolarHBondContact O-N 3.04Å; K199-C203 WeakPolarHBondContact O-CA 3.26Å; K199-C203 PolarHBondContact O-N 2.94Å; K199-S212 VanDerWaalsContact NZ-CB 3.31Å; K199-S212 PolarHBondContact NZ-O 3.38Å; K199-S212 PolarHBondContact NZ-OG 2.96Å
200V46.4Very low47.2Very low67 Ų6782.8 Ų82.841%0.40642%0.418SS..Hα-helixtrans-98-35.5176.9164.90000112.2R196 R197 L198 L202 C203R196-V200 WeakPolarHBondContact O-CB 3.19Å; R196-V200 VanDerWaalsContact O-CG2 3.23Å; R196-V200 WeakPolarHBondContact O-CG2 3.34Å; R196-V200 PolarHBondContact O-N 3.15Å; R197-V200 PolarHBondContact O-N 2.56Å; L198-V200 PolarHBondContact O-N 2.65Å; L198-V200 VanDerWaalsContact O-N 3.15Å; V200-L202 VanDerWaalsContact C-N 3.35Å; V200-C203 WeakPolarHBondContact O-CB 3.37Å; V200-C203 PolarHBondContact O-N 3.12Å
201F42.7Very low46.7Very low136 Ų13683.5 Ų83.560%0.59642%0.421SS*.Hα-helixtrans-66.1-40.8167.3-88.1-93.4000110.5C155 R197 L198 C203C155-F201 HydrophobicContact CB-CE2 4.11Å; R197-F201 PolarHBondContact O-N 3.29Å; L198-F201 PolarHBondContact O-N 3.13Å; F201-C203 VanDerWaalsContact C-N 3.28Å; F201-C203 PolarHBondContact O-N 3.31Å
202L42.7Very low46.8Very low50 Ų5084.8 Ų84.826%0.26243%0.43SS..THydrogen-bonded Turntrans-88.928.7172.8-70.584.9000112.9L198 V200 C204 T205L198-L202 WeakPolarHBondContact O-CB 3.24Å; L198-L202 WeakPolarHBondContact O-CD1 3.33Å; L198-L202 PolarHBondContact O-N 2.89Å; V200-L202 VanDerWaalsContact C-N 3.35Å; L202-C204 PolarHBondContact O-N 2.87Å; L202-C204 VanDerWaalsContact O-N 3.11Å; L202-T205 PolarHBondContact O-N 3.34Å; L202-T205 PolarHBondContact O-OG1 3.39Å; L202-T205 VanDerWaalsContact O-OG1 3.07Å
203C35.6Very low46.9Very low94 Ų9485.1 Ų85.164%0.63543%0.428SS*.THydrogen-bonded Turntrans-62.3-24-174.2-165.60000113.7K199 V200 F201 T205K199-C203 WeakPolarHBondContact O-CA 3.26Å; K199-C203 PolarHBondContact O-N 2.94Å; V200-C203 WeakPolarHBondContact O-CB 3.37Å; V200-C203 PolarHBondContact O-N 3.12Å; F201-C203 VanDerWaalsContact C-N 3.28Å; F201-C203 PolarHBondContact O-N 3.31Å; C203-T205 PolarHBondContact O-N 3.28Å
204C32.5Very low46.7Very low127 Ų12785.5 Ų85.586%0.85843%0.431SS*.THydrogen-bonded Turntrans-74.2-8.5175.5-61.60000113.7L202L202-C204 PolarHBondContact O-N 2.87Å; L202-C204 VanDerWaalsContact O-N 3.11Å
205T36.7Very low46.8Very low26 Ų2682.8 Ų82.816%0.1642%0.422CS..  trans-113.476.3-172.175.50000111.8L202 C203 T207 Q909L202-T205 PolarHBondContact O-N 3.34Å; L202-T205 PolarHBondContact O-OG1 3.39Å; L202-T205 VanDerWaalsContact O-OG1 3.07Å; C203-T205 PolarHBondContact O-N 3.28Å; T205-T207 PolarHBondContact O-N 2.86Å; T205-Q909 HydrophobicContact CG2-CG 3.59Å
206R34.8Very low47Very low250 Ų25084.1 Ų84.194%0.94343%0.431SS*.  trans-72.586.7177.5-177.4-178.9168.7171.7-3.5111.6
207T36.5Very low46.9Very low80 Ų8083.7 Ų83.749%0.49143%0.433SS..  trans-109.8171.1175.457.30000113T205 Q211T205-T207 PolarHBondContact O-N 2.86Å; T207-Q211 PolarHBondContact OG1-OE1 3.22Å
208K43.5Very low46.8Very low179 Ų17983.5 Ų83.578%0.77843%0.434SS*.  trans-71.2156-167.8-63.9177.6180176.10113.6S210 Q211K208-S210 VanDerWaalsContact C-N 3.26Å; K208-S210 PolarHBondContact O-N 3.21Å; K208-Q211 PolarHBondContact O-N 3.12Å
209D47.5Very low47Very low134 Ų13481.9 Ų81.972%0.71743%0.426SS*.THydrogen-bonded Turntrans-54.5-32.3-170.8-50.3-77.6000114.8Q211 S212D209-Q211 PolarHBondContact O-N 2.91Å; D209-Q211 VanDerWaalsContact O-N 3.1Å; D209-S212 WeakPolarHBondContact O-CA 3.42Å; D209-S212 WeakPolarHBondContact O-CB 3.4Å; D209-S212 PolarHBondContact O-N 3.11Å
210S46.1Very low47.4Very low81 Ų8182.9 Ų82.957%0.56643%0.429SS*.Hα-helixtrans-58.4-24.7176.9165.60000114.9K208K208-S210 VanDerWaalsContact C-N 3.26Å; K208-S210 PolarHBondContact O-N 3.21Å
211Q46.1Very low47.9Very low66 Ų6682.5 Ų82.531%0.30842%0.424SS..Hα-helixtrans-83-19.5171.7-78-170.7-25.200113T207 K208 D209 D213 Y215T207-Q211 PolarHBondContact OG1-OE1 3.22Å; K208-Q211 PolarHBondContact O-N 3.12Å; D209-Q211 PolarHBondContact O-N 2.91Å; D209-Q211 VanDerWaalsContact O-N 3.1Å; Q211-D213 PolarHBondContact O-N 3Å; Q211-Y215 WeakPolarHBondContact O-CD2 3.41Å
212S54.7Low48.7Very low36 Ų3681.2 Ų81.225%0.25242%0.418SS..Hα-helixtrans-63.4-33.3177.5143.50000111.8K199 D209 S216K199-S212 VanDerWaalsContact NZ-CB 3.31Å; K199-S212 PolarHBondContact NZ-O 3.38Å; K199-S212 PolarHBondContact NZ-OG 2.96Å; D209-S212 WeakPolarHBondContact O-CA 3.42Å; D209-S212 WeakPolarHBondContact O-CB 3.4Å; D209-S212 PolarHBondContact O-N 3.11Å; S212-S216 PolarHBondContact O-OG 3.5Å; S212-S216 VanDerWaalsContact O-OG 3.07Å
213D59.4Low49.5Very low95 Ų9579.6 Ų79.651%0.50841%0.412SS..Hα-helixtrans-74.2-44.8-174-53.8-31.8000111.5Q211 Y215 S216 E217Q211-D213 PolarHBondContact O-N 3Å; D213-Y215 VanDerWaalsContact C-N 3.28Å; D213-Y215 PolarHBondContact O-N 2.74Å; D213-S216 WeakPolarHBondContact O-CA 3.29Å; D213-S216 VanDerWaalsContact O-CB 3.25Å; D213-S216 WeakPolarHBondContact O-CB 3.18Å; D213-S216 PolarHBondContact O-N 3.27Å; D213-S216 PolarHBondContact O-OG 3.03Å; D213-E217 PolarHBondContact O-N 3.19Å; D213-E217 VanDerWaalsContact O-N 3.09Å
214A51.2Low50.7Low10 Ų1077.3 Ų77.38%0.08339%0.392CS..Hα-helixtrans-56.9-38.3176.200000112.9S216 E217 I218 P403A214-S216 VanDerWaalsContact C-N 3.25Å; A214-S216 PolarHBondContact O-N 3.34Å; A214-E217 PolarHBondContact O-N 2.77Å; A214-I218 WeakPolarHBondContact O-CG1 3.42Å; A214-I218 PolarHBondContact O-N 3.13Å; A214-P403 HydrophobicContact CB-CB 4.45Å
215Y55.5Low52.3Low44 Ų4472.9 Ų72.917%0.17336%0.358CS..Hα-helixtrans-67.5-23173.4-67.6-59.3000113.5L198 Q211 D213 A219 P403L198-Y215 HydrophobicContact CB-CD1 4.3Å; L198-Y215 HydrophobicContact CB-CG 4.48Å; L198-Y215 HydrophobicContact CD1-CD1 3.98Å; L198-Y215 HydrophobicContact CD1-CG 4.45Å; L198-Y215 HydrophobicContact CD2-CD1 4.37Å; L198-Y215 HydrophobicContact CG-CD1 4.44Å; Q211-Y215 WeakPolarHBondContact O-CD2 3.41Å; D213-Y215 VanDerWaalsContact C-N 3.28Å; D213-Y215 PolarHBondContact O-N 2.74Å; Y215-A219 WeakPolarHBondContact O-CB 3.5Å; Y215-A219 PolarHBondContact O-N 2.98Å; Y215-P403 HydrophobicContact CE1-CB 4.45Å; Y215-P403 HydrophobicContact CE1-CG 4.32Å
216S58.3Low53.5Low32 Ų3273.1 Ų73.122%0.22436%0.357CS..Hα-helixtrans-76.6-41.2172.3-19.90000111.6S212 D213 A214 A219 Y220S212-S216 PolarHBondContact O-OG 3.5Å; S212-S216 VanDerWaalsContact O-OG 3.07Å; D213-S216 WeakPolarHBondContact O-CA 3.29Å; D213-S216 VanDerWaalsContact O-CB 3.25Å; D213-S216 WeakPolarHBondContact O-CB 3.18Å; D213-S216 PolarHBondContact O-N 3.27Å; D213-S216 PolarHBondContact O-OG 3.03Å; A214-S216 VanDerWaalsContact C-N 3.25Å; A214-S216 PolarHBondContact O-N 3.34Å; S216-A219 CarbonylContact O-C 3.57Å; S216-A219 WeakPolarHBondContact O-CB 3.43Å; S216-A219 PolarHBondContact O-N 3.13Å; S216-Y220 WeakPolarHBondContact O-CB 3.38Å; S216-Y220 PolarHBondContact O-N 3.45Å
217E56.2Low54.7Low96 Ų9663.9 Ų63.945%0.44932%0.322SS..Hα-helixtrans-65.7-47.5177.7-65.4-54.1140.900111.6D213 A214 A219 Y220 L221 L407D213-E217 PolarHBondContact O-N 3.19Å; D213-E217 VanDerWaalsContact O-N 3.09Å; A214-E217 PolarHBondContact O-N 2.77Å; E217-A219 VanDerWaalsContact C-N 3.28Å; E217-A219 PolarHBondContact O-N 3.07Å; E217-Y220 WeakPolarHBondContact O-CB 3.3Å; E217-Y220 PolarHBondContact O-N 2.91Å; E217-Y220 VanDerWaalsContact O-N 3.11Å; E217-L221 WeakPolarHBondContact O-CG 3.33Å; E217-L221 PolarHBondContact O-N 3.43Å; E217-L407 HydrophobicContact CB-CD1 3.66Å; E217-L407 HydrophobicContact CB-CD2 4.27Å; E217-L407 HydrophobicContact CG-CD1 4.41Å; E217-L407 HydrophobicContact CG-CD2 4.34Å
218I56Low55.5Low29 Ų2963.3 Ų63.315%0.14932%0.316CS..Hα-helixtrans-57.8-44.2173.2-63.8165.8000109.9A214 Y220 L221 F222 A406 L410A214-I218 WeakPolarHBondContact O-CG1 3.42Å; A214-I218 PolarHBondContact O-N 3.13Å; I218-Y220 PolarHBondContact O-N 3.41Å; I218-L221 PolarHBondContact O-N 2.83Å; I218-F222 HydrophobicContact CG2-CD2 3.96Å; I218-F222 HydrophobicContact CG2-CE2 4.1Å; I218-F222 WeakPolarHBondContact O-CD2 3.47Å; I218-F222 PolarHBondContact O-N 3.39Å; I218-A406 HydrophobicContact CD1-CB 4.42Å; I218-L410 HydrophobicContact CG1-CD1 4.02Å; I218-L410 HydrophobicContact CG2-CD1 4.37Å
219A55.3Low56.1Low4 Ų456.7 Ų56.73%0.03329%0.289CS..Hα-helixtrans-64.5-35.1176.600000113.8A191 W194 Y215 S216 E217 A223A191-A219 HydrophobicContact CB-CB 4.48Å; W194-A219 HydrophobicContact CB-CB 3.48Å; W194-A219 VanDerWaalsContact CB-CB 3.48Å; W194-A219 HydrophobicContact CG-CB 4.38Å; Y215-A219 WeakPolarHBondContact O-CB 3.5Å; Y215-A219 PolarHBondContact O-N 2.98Å; S216-A219 CarbonylContact O-C 3.57Å; S216-A219 WeakPolarHBondContact O-CB 3.43Å; S216-A219 PolarHBondContact O-N 3.13Å; E217-A219 VanDerWaalsContact C-N 3.28Å; E217-A219 PolarHBondContact O-N 3.07Å; A219-A223 VanDerWaalsContact O-CB 3.24Å; A219-A223 WeakPolarHBondContact O-CB 3.41Å; A219-A223 PolarHBondContact O-N 2.88Å
220Y57.1Low56.8Low105 Ų10552.1 Ų52.141%0.41226%0.264SS..Hα-helixtrans-67.6-47.2175.6178.1-88.3000110.5S216 E217 I218 F222 A223 E224S216-Y220 WeakPolarHBondContact O-CB 3.38Å; S216-Y220 PolarHBondContact O-N 3.45Å; E217-Y220 WeakPolarHBondContact O-CB 3.3Å; E217-Y220 PolarHBondContact O-N 2.91Å; E217-Y220 VanDerWaalsContact O-N 3.11Å; I218-Y220 PolarHBondContact O-N 3.41Å; Y220-F222 PolarHBondContact O-N 3.27Å; Y220-A223 CarbonylContact O-C 3.6Å; Y220-A223 WeakPolarHBondContact O-CA 3.49Å; Y220-A223 WeakPolarHBondContact O-CB 3.25Å; Y220-A223 PolarHBondContact O-N 2.7Å; Y220-A223 VanDerWaalsContact O-N 3.07Å; Y220-E224 PolarHBondContact O-N 3.4Å
221L57.4Low57.8Low58 Ų5849.5 Ų49.530%0.30424%0.244SC..Hα-helixtrans-62.8-41.4178.2-69.3162.4000112.2E217 I218 E224 F225 L407 L410E217-L221 WeakPolarHBondContact O-CG 3.33Å; E217-L221 PolarHBondContact O-N 3.43Å; I218-L221 PolarHBondContact O-N 2.83Å; L221-E224 PolarHBondContact O-N 3.02Å; L221-F225 WeakPolarHBondContact O-CB 3.23Å; L221-F225 PolarHBondContact O-N 2.65Å; L221-L407 HydrophobicContact CD1-CD1 4.33Å; L221-L410 HydrophobicContact CD1-CB 3.93Å; L221-L410 HydrophobicContact CD1-CD1 4.22Å
222F60.3Low59Low110 Ų11046.6 Ų46.648%0.48223%0.231SC..Hα-helixtrans-64.7-38.2171-91.9-96000112.3I218 Y220 F226I218-F222 HydrophobicContact CG2-CD2 3.96Å; I218-F222 HydrophobicContact CG2-CE2 4.1Å; I218-F222 WeakPolarHBondContact O-CD2 3.47Å; I218-F222 PolarHBondContact O-N 3.39Å; Y220-F222 PolarHBondContact O-N 3.27Å; F222-F226 HydrophobicContact CD1-CE2 4.28Å; F222-F226 WeakPolarHBondContact O-CD2 3.26Å; F222-F226 PolarHBondContact O-N 2.69Å; F222-F226 VanDerWaalsContact O-N 3.15Å
223A58.8Low59.7Low15 Ų1547.3 Ų47.312%0.12424%0.235CC..Hα-helixtrans-68.3-34.6175.200000112.5A219 Y220 F226 R227A219-A223 VanDerWaalsContact O-CB 3.24Å; A219-A223 WeakPolarHBondContact O-CB 3.41Å; A219-A223 PolarHBondContact O-N 2.88Å; Y220-A223 CarbonylContact O-C 3.6Å; Y220-A223 WeakPolarHBondContact O-CA 3.49Å; Y220-A223 WeakPolarHBondContact O-CB 3.25Å; Y220-A223 PolarHBondContact O-N 2.7Å; Y220-A223 VanDerWaalsContact O-N 3.07Å; A223-F226 CarbonylContact O-C 3.57Å; A223-R227 WeakPolarHBondContact O-CA 3.36Å; A223-R227 WeakPolarHBondContact O-CB 3.41Å; A223-R227 PolarHBondContact O-N 3.02Å
224E61.3Low60.5Low47 Ų4743.9 Ų43.922%0.2222%0.218CC..Hα-helixtrans-69.1-46.5173.6174.9144.6-13500111.5Y220 L221 F226 R227Y220-E224 PolarHBondContact O-N 3.4Å; L221-E224 PolarHBondContact O-N 3.02Å; E224-F226 PolarHBondContact O-N 3.33Å; E224-R227 VanDerWaalsContact O-CB 3.26Å; E224-R227 WeakPolarHBondContact O-CB 3.36Å; E224-R227 PolarHBondContact O-N 3.42Å; E224-R227 IonicContact OE1-CZ 2.8Å; E224-R227 IonicContact OE1-NH1 3.73Å; E224-R227 PolarHBondContact OE1-NH1 3.06Å
225F65.6Low61.9Low33 Ų3343.4 Ų43.415%0.14521%0.214CC..Hα-helixtrans-59.9-30.1177.5-175-107.4000112.8L221 L534 F537 R538L221-F225 WeakPolarHBondContact O-CB 3.23Å; L221-F225 PolarHBondContact O-N 2.65Å; F225-L534 HydrophobicContact CD2-CD2 4.03Å; F225-L534 HydrophobicContact CD2-CG 4.27Å; F225-L534 HydrophobicContact CE2-CD1 4.42Å; F225-L534 HydrophobicContact CE2-CD2 3.84Å; F225-L534 HydrophobicContact CE2-CG 3.57Å; F225-L534 HydrophobicContact CZ-CD1 4.19Å; F225-L534 HydrophobicContact CZ-CD2 4.36Å; F225-L534 HydrophobicContact CZ-CG 3.82Å; F225-F537 HydrophobicContact CZ-CD1 4.25Å; F225-R538 HydrophobicContact CE1-CB 4.47Å; F225-R538 HydrophobicContact CE2-CB 3.74Å; F225-R538 HydrophobicContact CE2-CG 4.19Å; F225-R538 HydrophobicContact CZ-CB 3.56Å; F225-R538 HydrophobicContact CZ-CG 4.06Å; F225-R538 VanDerWaalsContact O-CD 3.32Å; F225-R538 WeakPolarHBondContact O-CD 3.25Å; F225-R538 PolarHBondContact O-NE 3.35Å; F225-R538 PolarHBondContact O-NH1 3.07Å
226F62.8Low63.1Low32 Ų3243.1 Ų43.114%0.1422%0.215CC..THydrogen-bonded Turntrans-106.713.7173.8-64.8-69.2000114.7F222 A223 E224 D228 L229 I231 I236 L541F222-F226 HydrophobicContact CD1-CE2 4.28Å; F222-F226 WeakPolarHBondContact O-CD2 3.26Å; F222-F226 PolarHBondContact O-N 2.69Å; F222-F226 VanDerWaalsContact O-N 3.15Å; A223-F226 CarbonylContact O-C 3.57Å; E224-F226 PolarHBondContact O-N 3.33Å; F226-D228 VanDerWaalsContact C-N 3.28Å; F226-D228 PolarHBondContact O-N 3.44Å; F226-L229 HydrophobicContact CD1-CD1 3.94Å; F226-L229 WeakPolarHBondContact O-CA 3.36Å; F226-L229 VanDerWaalsContact O-CB 3.32Å; F226-L229 WeakPolarHBondContact O-CB 3.44Å; F226-L229 PolarHBondContact O-N 2.68Å; F226-I231 HydrophobicContact CD1-CD1 4.28Å; F226-I236 HydrophobicContact CD2-CD1 4.47Å; F226-I236 HydrophobicContact CE1-CD1 4.17Å; F226-I236 HydrophobicContact CE1-CG1 4.34Å; F226-I236 HydrophobicContact CE2-CD1 3.71Å; F226-I236 HydrophobicContact CZ-CD1 3.54Å; F226-I236 HydrophobicContact CZ-CG1 4.09Å; F226-L541 HydrophobicContact CE1-CD2 4.37Å
227R58.7Low64.1Low56 Ų5643.3 Ų43.321%0.21121%0.213CC..THydrogen-bonded Turntrans-53.4-37-166.7-174.9179.761.3-139.7-10.4115.8A223 E224 L229 L589A223-R227 WeakPolarHBondContact O-CA 3.36Å; A223-R227 WeakPolarHBondContact O-CB 3.41Å; A223-R227 PolarHBondContact O-N 3.02Å; E224-R227 VanDerWaalsContact O-CB 3.26Å; E224-R227 WeakPolarHBondContact O-CB 3.36Å; E224-R227 PolarHBondContact O-N 3.42Å; E224-R227 IonicContact OE1-CZ 2.8Å; E224-R227 IonicContact OE1-NH1 3.73Å; E224-R227 PolarHBondContact OE1-NH1 3.06Å; R227-L229 VanDerWaalsContact C-N 3.28Å; R227-L589 VanDerWaalsContact NH1-CD2 3.32Å
228D53.4Low65.4Low67 Ų6738.7 Ų38.736%0.35819%0.192SC..THydrogen-bonded Turntrans-93.68.1-173.7-47-65.7000112R183 F226 R538R183-D228 IonicContact NH2-OD1 3.3Å; R183-D228 PolarHBondContact NH2-OD1 3.11Å; F226-D228 VanDerWaalsContact C-N 3.28Å; F226-D228 PolarHBondContact O-N 3.44Å; D228-R538 IonicContact OD2-CZ 3.55Å; D228-R538 IonicContact OD2-NH2 3.94Å; D228-R538 PolarHBondContact OD2-NH2 2.75Å
229L57.4Low66.8Low40 Ų4037.3 Ų37.321%0.20919%0.185CC..  trans-128.1107.4-163.6-55.1169.8000110.8F226 R227 I231 L542F226-L229 HydrophobicContact CD1-CD1 3.94Å; F226-L229 WeakPolarHBondContact O-CA 3.36Å; F226-L229 VanDerWaalsContact O-CB 3.32Å; F226-L229 WeakPolarHBondContact O-CB 3.44Å; F226-L229 PolarHBondContact O-N 2.68Å; R227-L229 VanDerWaalsContact C-N 3.28Å; L229-I231 VanDerWaalsContact C-N 3.29Å; L229-I231 HydrophobicContact CB-CB 4.46Å; L229-I231 HydrophobicContact CB-CD1 3.84Å; L229-I231 HydrophobicContact CB-CG1 4.02Å; L229-I231 HydrophobicContact CD1-CD1 4.03Å; L229-I231 HydrophobicContact CG-CD1 4.41Å; L229-I231 PolarHBondContact O-N 3.34Å; L229-L542 HydrophobicContact CD1-CD1 4.06Å; L229-L542 HydrophobicContact CD1-CD2 3.77Å; L229-L542 HydrophobicContact CD1-CG 4.28Å; L229-L542 HydrophobicContact CD2-CD1 3.91Å; L229-L542 HydrophobicContact CD2-CD2 3.46Å; L229-L542 VanDerWaalsContact CD2-CD2 3.46Å; L229-L542 HydrophobicContact CD2-CG 4.32Å; L229-L542 HydrophobicContact CG-CD2 4.21Å
230D61.4Low68.2Low38 Ų3837.8 Ų37.820%0.20319%0.186CC..  trans-64.595158-80.8-11.3000107.6M1 R10 F164 R168M1-D230 CarbonylContact C-O 3.59Å; M1-D230 VanDerWaalsContact CA-O 3.3Å; M1-D230 WeakPolarHBondContact CA-O 3.44Å; M1-D230 WeakPolarHBondContact CB-O 3.05Å; M1-D230 PolarHBondContact N-O 3.23Å; M1-D230 CarbonylContact O-C 3.59Å; R10-D230 IonicContact CZ-OD1 3.41Å; R10-D230 IonicContact NH1-OD1 2.67Å; R10-D230 PolarHBondContact NH1-OD1 3.19Å; R10-D230 IonicContact NH2-OD1 3.48Å; R10-D230 PolarHBondContact NH2-OD1 3.36Å; F164-D230 WeakPolarHBondContact CZ-OD1 3.31Å; R168-D230 IonicContact NH1-OD2 2.83Å; R168-D230 PolarHBondContact NH1-OD2 2.92Å
231I67.1Low69.5Low26 Ų2633 Ų3313%0.13317%0.168CC..  trans-131.1143179-83.6178.9000109.2M1 F226 L229 D235 I236 L542 L545M1-I231 HydrophobicContact SD-CG1 4.46Å; F226-I231 HydrophobicContact CD1-CD1 4.28Å; L229-I231 VanDerWaalsContact C-N 3.29Å; L229-I231 HydrophobicContact CB-CB 4.46Å; L229-I231 HydrophobicContact CB-CD1 3.84Å; L229-I231 HydrophobicContact CB-CG1 4.02Å; L229-I231 HydrophobicContact CD1-CD1 4.03Å; L229-I231 HydrophobicContact CG-CD1 4.41Å; L229-I231 PolarHBondContact O-N 3.34Å; I231-D235 HydrophobicContact CG2-CB 4.32Å; I231-I236 HydrophobicContact CG2-CD1 4.09Å; I231-I236 HydrophobicContact CG2-CG1 3.57Å; I231-L542 HydrophobicContact CD1-CD2 4.23Å; I231-L545 HydrophobicContact CD1-CD1 4.37Å
232V71Confident70.9Confident6 Ų631.2 Ų31.24%0.03616%0.159CC..  trans-102.6148.9170.5-176.70000108.3S234 D235 I236V232-S234 WeakPolarHBondContact CG1-OG 3.39Å; V232-S234 PolarHBondContact O-N 2.97Å; V232-S234 VanDerWaalsContact O-N 3.11Å; V232-D235 WeakPolarHBondContact CB-OD2 3.46Å; V232-D235 PolarHBondContact N-OD2 2.94Å; V232-D235 WeakPolarHBondContact O-CA 3.46Å; V232-D235 VanDerWaalsContact O-CB 3.3Å; V232-D235 WeakPolarHBondContact O-CB 3.4Å; V232-D235 PolarHBondContact O-N 3.35Å; V232-I236 PolarHBondContact O-N 3.25Å
233P69.9Low72.1Confident51 Ų5126.1 Ų26.133%0.33114%0.137SC..Hα-helixtrans-54.3-33.2-179.2-30.237.7000114.5W194 D235 I236 I237W194-P233 HydrophobicContact CH2-CG 4.03Å; P233-D235 VanDerWaalsContact C-N 3.3Å; P233-D235 PolarHBondContact O-N 2.86Å; P233-I236 WeakPolarHBondContact O-CB 3.42Å; P233-I236 PolarHBondContact O-N 3.3Å; P233-I236 VanDerWaalsContact O-N 3.13Å; P233-I237 PolarHBondContact O-N 3.13Å; P233-I237 VanDerWaalsContact O-N 3.15Å
234S75.2Confident73.5Confident22 Ų2229.2 Ų29.215%0.15415%0.145CC..Hα-helixtrans-66.2-26.1173.554.50000114.2D17 V232 I237 A238 K552D17-S234 WeakPolarHBondContact OD1-CB 3.45Å; D17-S234 PolarHBondContact OD1-OG 2.92Å; D17-S234 PolarHBondContact OD2-OG 3.06Å; D17-S234 VanDerWaalsContact OD2-OG 3.12Å; V232-S234 WeakPolarHBondContact CG1-OG 3.39Å; V232-S234 PolarHBondContact O-N 2.97Å; V232-S234 VanDerWaalsContact O-N 3.11Å; S234-I237 PolarHBondContact O-N 3.25Å; S234-A238 WeakPolarHBondContact O-CB 3.49Å; S234-A238 PolarHBondContact O-N 3.14Å; S234-K552 PolarHBondContact OG-NZ 2.68Å
235D81.4Confident74.5Confident1 Ų129.3 Ų29.31%0.00515%0.145CC..Hα-helixtrans-72.4-32.6171.9-51.3-34.2000110.7M1 I85 I231 V232 P233 A238 G239 L545 K552M1-D235 VanDerWaalsContact CB-OD2 3.27Å; M1-D235 WeakPolarHBondContact CB-OD2 3.27Å; M1-D235 HydrophobicContact SD-CB 3.75Å; I85-D235 WeakPolarHBondContact CG2-OD1 3.3Å; I231-D235 HydrophobicContact CG2-CB 4.32Å; V232-D235 WeakPolarHBondContact CB-OD2 3.46Å; V232-D235 PolarHBondContact N-OD2 2.94Å; V232-D235 WeakPolarHBondContact O-CA 3.46Å; V232-D235 VanDerWaalsContact O-CB 3.3Å; V232-D235 WeakPolarHBondContact O-CB 3.4Å; V232-D235 PolarHBondContact O-N 3.35Å; P233-D235 VanDerWaalsContact C-N 3.3Å; P233-D235 PolarHBondContact O-N 2.86Å; D235-A238 PolarHBondContact O-N 3.42Å; D235-G239 PolarHBondContact O-N 3.21Å; D235-L545 WeakPolarHBondContact O-CD2 3.38Å; D235-K552 IonicContact OD1-NZ 2.62Å; D235-K552 PolarHBondContact OD1-NZ 3.03Å
236I79.8Confident75.5Confident37 Ų3731.8 Ų31.819%0.1915%0.154CC..Hα-helixtrans-64.4-46.5172.6-54.1173.7000109.3F226 I231 V232 P233 G239 L240 L541F226-I236 HydrophobicContact CD2-CD1 4.47Å; F226-I236 HydrophobicContact CE1-CD1 4.17Å; F226-I236 HydrophobicContact CE1-CG1 4.34Å; F226-I236 HydrophobicContact CE2-CD1 3.71Å; F226-I236 HydrophobicContact CZ-CD1 3.54Å; F226-I236 HydrophobicContact CZ-CG1 4.09Å; I231-I236 HydrophobicContact CG2-CD1 4.09Å; I231-I236 HydrophobicContact CG2-CG1 3.57Å; V232-I236 PolarHBondContact O-N 3.25Å; P233-I236 WeakPolarHBondContact O-CB 3.42Å; P233-I236 PolarHBondContact O-N 3.3Å; P233-I236 VanDerWaalsContact O-N 3.13Å; I236-G239 PolarHBondContact O-N 3.25Å; I236-L240 HydrophobicContact CG2-CD1 4Å; I236-L240 HydrophobicContact CG2-CG 4.44Å; I236-L240 WeakPolarHBondContact O-CB 3.37Å; I236-L240 VanDerWaalsContact O-CG 3.31Å; I236-L240 WeakPolarHBondContact O-CG 3.38Å; I236-L240 PolarHBondContact O-N 2.94Å; I236-L541 HydrophobicContact CG2-CD2 4.39Å
237I79.9Confident76.7Confident36 Ų3630.6 Ų30.619%0.18515%0.149CC..Hα-helixtrans-58.7-48.8175.7-63.7172.1000110.8P233 S234 G239 L240 V241 I556 L923P233-I237 PolarHBondContact O-N 3.13Å; P233-I237 VanDerWaalsContact O-N 3.15Å; S234-I237 PolarHBondContact O-N 3.25Å; I237-G239 VanDerWaalsContact C-N 3.32Å; I237-G239 PolarHBondContact O-N 2.89Å; I237-L240 WeakPolarHBondContact O-CB 3.42Å; I237-L240 PolarHBondContact O-N 3.5Å; I237-V241 WeakPolarHBondContact O-CG2 3.22Å; I237-V241 PolarHBondContact O-N 3.15Å; I237-I556 HydrophobicContact CG2-CD1 4.4Å; I237-I556 HydrophobicContact CG2-CG1 4.37Å; I237-L923 HydrophobicContact CG2-CD1 4.11Å; I237-L923 HydrophobicContact CG2-CD2 3.84Å; I237-L923 HydrophobicContact CG2-CG 4.47Å
238A83.5Confident77.9Confident0 Ų034.7 Ų34.70%016%0.164CC..Hα-helixtrans-61.5-39.3176.600000112.5I85 S234 D235 V241 L242 K552 I555 I556I85-A238 HydrophobicContact CD1-CB 4.06Å; S234-A238 WeakPolarHBondContact O-CB 3.49Å; S234-A238 PolarHBondContact O-N 3.14Å; D235-A238 PolarHBondContact O-N 3.42Å; A238-V241 PolarHBondContact O-N 3.25Å; A238-L242 VanDerWaalsContact O-CG 3.32Å; A238-L242 WeakPolarHBondContact O-CG 3.46Å; A238-L242 PolarHBondContact O-N 3.31Å; A238-K552 HydrophobicContact CB-CD 4.33Å; A238-K552 HydrophobicContact CB-CG 4.07Å; A238-I555 HydrophobicContact CB-CG2 4.21Å; A238-I556 HydrophobicContact CB-CG1 4.3Å
239G85.2Confident79.3Confident0 Ų034.4 Ų34.40%017%0.171CC..Hα-helixtrans-65.6-40.6175.600000112.9D235 I236 I237 V241 L242 L243D235-G239 PolarHBondContact O-N 3.21Å; I236-G239 PolarHBondContact O-N 3.25Å; I237-G239 VanDerWaalsContact C-N 3.32Å; I237-G239 PolarHBondContact O-N 2.89Å; G239-V241 VanDerWaalsContact C-N 3.34Å; G239-L242 PolarHBondContact O-N 3.22Å; G239-L243 VanDerWaalsContact O-CB 3.26Å; G239-L243 WeakPolarHBondContact O-CB 3.26Å; G239-L243 PolarHBondContact O-N 3.37Å
240L85.1Confident80.7Confident13 Ų1338.8 Ų38.87%0.06819%0.188CC..Hα-helixtrans-61.5-41.4173.9-75.9163.1000111.5I236 I237 L243 R244 F537 I642 F921I236-L240 HydrophobicContact CG2-CD1 4Å; I236-L240 HydrophobicContact CG2-CG 4.44Å; I236-L240 WeakPolarHBondContact O-CB 3.37Å; I236-L240 VanDerWaalsContact O-CG 3.31Å; I236-L240 WeakPolarHBondContact O-CG 3.38Å; I236-L240 PolarHBondContact O-N 2.94Å; I237-L240 WeakPolarHBondContact O-CB 3.42Å; I237-L240 PolarHBondContact O-N 3.5Å; L240-L243 PolarHBondContact O-N 3.03Å; L240-R244 VanDerWaalsContact O-CB 3.29Å; L240-R244 WeakPolarHBondContact O-CB 3.2Å; L240-R244 PolarHBondContact O-N 3.3Å; L240-F537 HydrophobicContact CD2-CE2 3.8Å; L240-F537 HydrophobicContact CD2-CZ 3.75Å; L240-I642 HydrophobicContact CB-CG2 4.33Å; L240-I642 HydrophobicContact CD2-CD1 3.74Å; L240-I642 HydrophobicContact CD2-CG1 4.25Å; L240-I642 HydrophobicContact CD2-CG2 3.97Å; L240-F921 HydrophobicContact CD1-CD1 3.87Å; L240-F921 HydrophobicContact CD1-CE1 3.61Å
241V83.8Confident81.8Confident6 Ų639 Ų394%0.03619%0.187CC..Hα-helixtrans-62.1-50.9174.5171.60000111.4I237 A238 G239 L243 R244 Q245 I555 A559 L923I237-V241 WeakPolarHBondContact O-CG2 3.22Å; I237-V241 PolarHBondContact O-N 3.15Å; A238-V241 PolarHBondContact O-N 3.25Å; G239-V241 VanDerWaalsContact C-N 3.34Å; V241-L243 VanDerWaalsContact C-N 3.31Å; V241-L243 PolarHBondContact O-N 3.05Å; V241-R244 PolarHBondContact O-N 3.42Å; V241-Q245 WeakPolarHBondContact O-CG 3.37Å; V241-Q245 PolarHBondContact O-N 3.49Å; V241-I555 HydrophobicContact CB-CG2 3.99Å; V241-I555 HydrophobicContact CG1-CG2 3.76Å; V241-A559 HydrophobicContact CB-CB 4.24Å; V241-A559 HydrophobicContact CG1-CB 3.66Å; V241-A559 HydrophobicContact CG2-CB 3.48Å; V241-A559 VanDerWaalsContact CG2-CB 3.48Å; V241-L923 HydrophobicContact CG2-CD1 3.41Å; V241-L923 VanDerWaalsContact CG2-CD1 3.41Å
242L86.7Confident82.5Confident19 Ų1941.6 Ų41.610%0.09920%0.2CC..Hα-helixtrans-60.9-41178.2-68.6164.9000111.5I85 A238 G239 Q245 R246 V544 L545 I555I85-L242 HydrophobicContact CD1-CD1 4.42Å; A238-L242 VanDerWaalsContact O-CG 3.32Å; A238-L242 WeakPolarHBondContact O-CG 3.46Å; A238-L242 PolarHBondContact O-N 3.31Å; G239-L242 PolarHBondContact O-N 3.22Å; L242-Q245 PolarHBondContact O-N 3.42Å; L242-R246 WeakPolarHBondContact O-CB 3.33Å; L242-R246 PolarHBondContact O-N 3.34Å; L242-V544 HydrophobicContact CB-CB 3.88Å; L242-V544 HydrophobicContact CB-CG2 3.9Å; L242-V544 HydrophobicContact CD1-CB 4.49Å; L242-L545 HydrophobicContact CD1-CD2 4.36Å; L242-I555 HydrophobicContact CD1-CD1 4.18Å; L242-I555 HydrophobicContact CD2-CD1 4.31Å; L242-I555 HydrophobicContact CD2-CG1 4.36Å; L242-I555 HydrophobicContact CD2-CG2 4.08Å; L242-I555 HydrophobicContact CG-CD1 4.44Å; L242-I555 HydrophobicContact CG-CG2 3.86Å
243L86.9Confident83.2Confident4 Ų443.9 Ų43.92%0.02122%0.22CC..Hα-helixtrans-67.1-40.8178-173.356.6000111.5G239 L240 V241 R246 Q247 F537 Q540 V544 I642G239-L243 VanDerWaalsContact O-CB 3.26Å; G239-L243 WeakPolarHBondContact O-CB 3.26Å; G239-L243 PolarHBondContact O-N 3.37Å; L240-L243 PolarHBondContact O-N 3.03Å; V241-L243 VanDerWaalsContact C-N 3.31Å; V241-L243 PolarHBondContact O-N 3.05Å; L243-R246 PolarHBondContact O-N 2.91Å; L243-Q247 HydrophobicContact CD1-CG 4.27Å; L243-Q247 HydrophobicContact CG-CG 4.42Å; L243-Q247 VanDerWaalsContact O-CB 3.27Å; L243-Q247 WeakPolarHBondContact O-CB 3.26Å; L243-Q247 VanDerWaalsContact O-CG 3.3Å; L243-Q247 WeakPolarHBondContact O-CG 3.41Å; L243-Q247 PolarHBondContact O-N 3.12Å; L243-F537 HydrophobicContact CD2-CD2 3.83Å; L243-F537 HydrophobicContact CD2-CE2 3.83Å; L243-Q540 HydrophobicContact CD1-CB 3.91Å; L243-Q540 HydrophobicContact CD2-CB 4.13Å; L243-V544 HydrophobicContact CB-CG2 4.27Å; L243-V544 HydrophobicContact CD1-CG1 4.35Å; L243-I642 HydrophobicContact CB-CG1 4.44Å; L243-I642 HydrophobicContact CD2-CD1 4.41Å; L243-I642 HydrophobicContact CD2-CG1 3.99Å; L243-I642 HydrophobicContact CG-CG1 4.09Å
244R86.6Confident84Confident79 Ų7943.2 Ų43.230%0.29822%0.215SC..Hα-helixtrans-60.4-43172-178.5178.3175.7-146.41.8111.8L240 V241 R248 I642 P644L240-R244 VanDerWaalsContact O-CB 3.29Å; L240-R244 WeakPolarHBondContact O-CB 3.2Å; L240-R244 PolarHBondContact O-N 3.3Å; V241-R244 PolarHBondContact O-N 3.42Å; R244-R248 WeakPolarHBondContact O-CB 2.99Å; R244-R248 PolarHBondContact O-N 2.8Å; R244-I642 HydrophobicContact CB-CB 4.03Å; R244-I642 HydrophobicContact CB-CG2 3.94Å; R244-P644 VanDerWaalsContact CZ-CD 3.45Å
245Q83.9Confident84.3Confident49 Ų4945.6 Ų45.623%0.22923%0.226CC..Hα-helixtrans-62.6-50.3175.7-73.9177.1-3.700111V241 L242 R248 A249 G558V241-Q245 WeakPolarHBondContact O-CG 3.37Å; V241-Q245 PolarHBondContact O-N 3.49Å; L242-Q245 PolarHBondContact O-N 3.42Å; Q245-R248 WeakPolarHBondContact O-CB 3.45Å; Q245-R248 PolarHBondContact O-N 2.78Å; Q245-R248 VanDerWaalsContact O-N 3.09Å; Q245-A249 PolarHBondContact O-N 2.94Å; Q245-G558 PolarHBondContact NE2-O 3.05Å
246R86.6Confident84.3Confident85 Ų8551.5 Ų51.532%0.32126%0.257SS..Hα-helixtrans-63.1-42.1178.3-173.7177.8-179.6-170.25.8113.2L242 L243 R248 A249 K250 D543L242-R246 WeakPolarHBondContact O-CB 3.33Å; L242-R246 PolarHBondContact O-N 3.34Å; L243-R246 PolarHBondContact O-N 2.91Å; R246-R248 VanDerWaalsContact C-N 3.27Å; R246-R248 PolarHBondContact O-N 3.45Å; R246-A249 PolarHBondContact O-N 2.86Å; R246-K250 WeakPolarHBondContact O-CB 3.16Å; R246-K250 PolarHBondContact O-N 2.81Å; R246-D543 IonicContact CZ-OD2 2.65Å; R246-D543 IonicContact NH1-OD2 2.8Å; R246-D543 PolarHBondContact NH1-OD2 2.69Å; R246-D543 IonicContact NH2-OD2 3.33Å; R246-D543 PolarHBondContact NH2-OD2 2.71Å
247Q87.3Confident84.6Confident8 Ų854.9 Ų54.94%0.03727%0.272CS..Hα-helixtrans-63.4-32.9173-77.2-172.8-0.800111.9L243 R251 V640 I642L243-Q247 HydrophobicContact CD1-CG 4.27Å; L243-Q247 HydrophobicContact CG-CG 4.42Å; L243-Q247 VanDerWaalsContact O-CB 3.27Å; L243-Q247 WeakPolarHBondContact O-CB 3.26Å; L243-Q247 VanDerWaalsContact O-CG 3.3Å; L243-Q247 WeakPolarHBondContact O-CG 3.41Å; L243-Q247 PolarHBondContact O-N 3.12Å; Q247-R251 VanDerWaalsContact C-NH1 3.27Å; Q247-R251 WeakPolarHBondContact O-CG 3.31Å; Q247-R251 PolarHBondContact O-N 3.47Å; Q247-R251 PolarHBondContact O-NH1 3.31Å; Q247-V640 PolarHBondContact NE2-O 3.17Å; Q247-I642 VanDerWaalsContact OE1-N 3.14Å
248R84.3Confident84.2Confident142 Ų14258 Ų5854%0.53630%0.304SS..Hα-helixtrans-69.8-49.6173-168.3179.4-168.9160.38.1110.9R244 Q245 R246 K250 R251 N252R244-R248 WeakPolarHBondContact O-CB 2.99Å; R244-R248 PolarHBondContact O-N 2.8Å; Q245-R248 WeakPolarHBondContact O-CB 3.45Å; Q245-R248 PolarHBondContact O-N 2.78Å; Q245-R248 VanDerWaalsContact O-N 3.09Å; R246-R248 VanDerWaalsContact C-N 3.27Å; R246-R248 PolarHBondContact O-N 3.45Å; R248-K250 PolarHBondContact O-N 3.34Å; R248-R251 PolarHBondContact O-N 3.22Å; R248-R251 VanDerWaalsContact O-N 3.11Å; R248-N252 PolarHBondContact O-N 3.23Å; R248-N252 PolarHBondContact O-OD1 2.62Å
249A83.3Confident83.9Confident61 Ų6165.7 Ų65.750%0.50435%0.345SS..Hα-helixtrans-55.9-47.9177.400000112.1Q245 R246 R251 N252 A253Q245-A249 PolarHBondContact O-N 2.94Å; R246-A249 PolarHBondContact O-N 2.86Å; A249-R251 VanDerWaalsContact C-N 3.32Å; A249-R251 PolarHBondContact O-N 3.03Å; A249-N252 PolarHBondContact O-N 3.02Å; A249-N252 VanDerWaalsContact O-N 3.17Å; A249-A253 PolarHBondContact O-N 3.03Å
250K85.8Confident83.5Confident131 Ų13168.5 Ų68.557%0.5736%0.36SS*.Hα-helixtrans-58-39175.4-175.7-173.7172.8-164.90113R246 R248 V254R246-K250 WeakPolarHBondContact O-CB 3.16Å; R246-K250 PolarHBondContact O-N 2.81Å; R248-K250 PolarHBondContact O-N 3.34Å; K250-V254 VanDerWaalsContact O-CG2 3.28Å; K250-V254 WeakPolarHBondContact O-CG2 3.46Å; K250-V254 PolarHBondContact O-N 3.11Å
251R84.3Confident83.5Confident44 Ų4472.6 Ų72.617%0.16638%0.382CS..Hα-helixtrans-72.3-37.3176.4-73.3-176.2-150.494.21.2112.3Q247 R248 A249 L255 F265Q247-R251 VanDerWaalsContact C-NH1 3.27Å; Q247-R251 WeakPolarHBondContact O-CG 3.31Å; Q247-R251 PolarHBondContact O-N 3.47Å; Q247-R251 PolarHBondContact O-NH1 3.31Å; R248-R251 PolarHBondContact O-N 3.22Å; R248-R251 VanDerWaalsContact O-N 3.11Å; A249-R251 VanDerWaalsContact C-N 3.32Å; A249-R251 PolarHBondContact O-N 3.03Å; R251-L255 PolarHBondContact O-N 3.14Å; R251-F265 HydrophobicContact CB-CD2 3.77Å; R251-F265 HydrophobicContact CB-CE2 3.83Å; R251-F265 HydrophobicContact CB-CG 4.13Å; R251-F265 HydrophobicContact CB-CZ 4.22Å; R251-F265 HydrophobicContact CG-CD1 3.95Å; R251-F265 HydrophobicContact CG-CD2 4.11Å; R251-F265 HydrophobicContact CG-CE1 3.91Å; R251-F265 HydrophobicContact CG-CE2 4.08Å; R251-F265 HydrophobicContact CG-CG 4.05Å; R251-F265 HydrophobicContact CG-CZ 3.98Å; R251-F265 VanDerWaalsContact O-CE2 3.27Å; R251-F265 WeakPolarHBondContact O-CE2 3.32Å
252N82.4Confident83.5Confident79 Ų7974.3 Ų74.342%0.42239%0.39SS..Hα-helixtrans-62.6-53174.6-79.540.2000110.8R248 A249 V254 L255 D256R248-N252 PolarHBondContact O-N 3.23Å; R248-N252 PolarHBondContact O-OD1 2.62Å; A249-N252 PolarHBondContact O-N 3.02Å; A249-N252 VanDerWaalsContact O-N 3.17Å; N252-V254 PolarHBondContact O-N 3.45Å; N252-V254 VanDerWaalsContact O-N 3.1Å; N252-L255 CarbonylContact O-C 3.56Å; N252-L255 WeakPolarHBondContact O-CA 3.39Å; N252-L255 WeakPolarHBondContact O-CB 3.11Å; N252-L255 PolarHBondContact O-N 2.83Å; N252-D256 VanDerWaalsContact C-OD2 3.23Å; N252-D256 VanDerWaalsContact O-CG 3.27Å; N252-D256 PolarHBondContact O-N 2.88Å
253A85.9Confident83.3Confident54 Ų5476 Ų7645%0.44640%0.399SS..Hα-helixtrans-55.8-33.218000000113.5A249 L255 D256 E257A249-A253 PolarHBondContact O-N 3.03Å; A253-L255 VanDerWaalsContact C-N 3.34Å; A253-D256 PolarHBondContact O-N 2.94Å; A253-E257 PolarHBondContact O-N 2.88Å; A253-E257 VanDerWaalsContact O-N 3.13Å
254V85.7Confident83.1Confident38 Ų3876.5 Ų76.523%0.2340%0.404CS..Hα-helixtrans-71.7-23.6174.7168.10000113.2K250 N252 N260 I262 F265K250-V254 VanDerWaalsContact O-CG2 3.28Å; K250-V254 WeakPolarHBondContact O-CG2 3.46Å; K250-V254 PolarHBondContact O-N 3.11Å; N252-V254 PolarHBondContact O-N 3.45Å; N252-V254 VanDerWaalsContact O-N 3.1Å; V254-N260 PolarHBondContact O-ND2 3.35Å; V254-I262 HydrophobicContact CG1-CD1 3.64Å; V254-F265 HydrophobicContact CB-CE2 4.27Å; V254-F265 HydrophobicContact CB-CZ 4.38Å; V254-F265 HydrophobicContact CG1-CE2 4.03Å; V254-F265 HydrophobicContact CG1-CZ 3.93Å
255L82.4Confident82.9Confident71 Ų7175.2 Ų75.237%0.37240%0.401SS..Hα-helixtrans-84.9-30.6169.8-62.6175000112.3R251 N252 A253 E257 I262 F265R251-L255 PolarHBondContact O-N 3.14Å; N252-L255 CarbonylContact O-C 3.56Å; N252-L255 WeakPolarHBondContact O-CA 3.39Å; N252-L255 WeakPolarHBondContact O-CB 3.11Å; N252-L255 PolarHBondContact O-N 2.83Å; A253-L255 VanDerWaalsContact C-N 3.34Å; L255-E257 VanDerWaalsContact C-N 3.29Å; L255-I262 HydrophobicContact CD2-CG2 4.03Å; L255-F265 HydrophobicContact CD1-CD2 4.04Å; L255-F265 HydrophobicContact CD2-CD2 3.99Å; L255-F265 HydrophobicContact CD2-CE2 4.1Å; L255-F265 HydrophobicContact CG-CD2 3.93Å; L255-F265 HydrophobicContact CG-CE2 4.04Å
256D81.1Confident82.9Confident125 Ų12573.6 Ų73.667%0.66839%0.393SS*.Hα-helixtrans-75-19178.8-56.9-43.8000112.2N252 A253 A258N252-D256 VanDerWaalsContact C-OD2 3.23Å; N252-D256 VanDerWaalsContact O-CG 3.27Å; N252-D256 PolarHBondContact O-N 2.88Å; A253-D256 PolarHBondContact O-N 2.94Å; D256-A258 PolarHBondContact O-N 3.42Å
257E86.8Confident82.7Confident108 Ų10869.8 Ų69.851%0.50538%0.38SS..SBendtrans-75.2104175.2176.7173.7-15100112.2A253 L255 N259 N260A253-E257 PolarHBondContact O-N 2.88Å; A253-E257 VanDerWaalsContact O-N 3.13Å; L255-E257 VanDerWaalsContact C-N 3.29Å; E257-N259 PolarHBondContact O-N 3.07Å; E257-N260 WeakPolarHBondContact CB-ND2 3.41Å; E257-N260 PolarHBondContact O-N 2.93Å; E257-N260 VanDerWaalsContact O-N 3.17Å; E257-N260 PolarHBondContact OE2-ND2 3.46Å
258A71.6Confident82.3Confident103 Ų10369.9 Ų69.985%0.85138%0.383SS*.THydrogen-bonded Turntrans-60.3-8.5-168.100000117.7D256D256-A258 PolarHBondContact O-N 3.42Å
259N76.2Confident82.2Confident161 Ų16164.1 Ų64.186%0.86136%0.362SS*.THydrogen-bonded Turntrans-105.44.8-179.4-78.8-22.4000114E257E257-N259 PolarHBondContact O-N 3.07Å
260N77.9Confident82.2Confident59 Ų5964 Ų6432%0.31636%0.357SS..  trans-84.7140-174.5-79.2-23.9000114.6V254 E257 I262V254-N260 PolarHBondContact O-ND2 3.35Å; E257-N260 WeakPolarHBondContact CB-ND2 3.41Å; E257-N260 PolarHBondContact O-N 2.93Å; E257-N260 VanDerWaalsContact O-N 3.17Å; E257-N260 PolarHBondContact OE2-ND2 3.46Å; N260-I262 PolarHBondContact O-N 3.46Å
261D83.6Confident82.1Confident98 Ų9858.2 Ų58.252%0.52433%0.332SS..SBendtrans-71.3-5.1172-86.9-42.5000113.9T272D261-T272 HydrophobicContact CB-CG2 4.48Å; D261-T272 VanDerWaalsContact O-CA 3.25Å; D261-T272 WeakPolarHBondContact O-CA 3.25Å; D261-T272 VanDerWaalsContact O-CB 3.27Å; D261-T272 WeakPolarHBondContact O-CB 3.46Å
262I84.9Confident82.2Confident43 Ų4357.9 Ų57.922%0.22134%0.335CS..EExtended strand (participates in β ladder)trans-89.1113.2-176.1-59.1169.6000109.2V254 L255 N260 F265 P270 V271 T272V254-I262 HydrophobicContact CG1-CD1 3.64Å; L255-I262 HydrophobicContact CD2-CG2 4.03Å; N260-I262 PolarHBondContact O-N 3.46Å; I262-F265 HydrophobicContact CD1-CZ 4.5Å; I262-F265 HydrophobicContact CG2-CD2 4.43Å; I262-F265 HydrophobicContact CG2-CE2 3.96Å; I262-F265 HydrophobicContact CG2-CZ 4.07Å; I262-P270 HydrophobicContact CD1-CB 3.94Å; I262-P270 HydrophobicContact CG1-CB 4.05Å; I262-P270 HydrophobicContact CG2-CB 3.79Å; I262-V271 CarbonylContact C-O 3.45Å; I262-V271 WeakPolarHBondContact CA-O 3.35Å; I262-T272 HydrophobicContact CG1-CG2 4.03Å
263L81.3Confident82.1Confident55 Ų5562.9 Ų62.929%0.28835%0.348SS..EExtended strand (participates in β ladder)trans-86.6-33-176-54.7175.7000112.8V271 R273 M680L263-V271 PolarHBondContact N-O 3.29Å; L263-R273 HydrophobicContact CD1-CG 4Å; L263-R273 HydrophobicContact CD2-CG 4.37Å; L263-R273 HydrophobicContact CG-CG 4.46Å; L263-M680 HydrophobicContact CD1-CE 4.16Å; L263-M680 HydrophobicContact CD1-SD 3.91Å; L263-M680 HydrophobicContact CD2-CE 4.3Å
264A82.5Confident81.9Confident14 Ų1466.5 Ų66.512%0.11636%0.359CS..EExtended strand (participates in β ladder)trans-163.7165.9-17600000111.6V271 V679A264-V271 PolarHBondContact O-N 2.84Å; A264-V679 HydrophobicContact CB-CG1 4.03Å
265F83.6Confident81.9Confident52 Ų5266 Ų6623%0.22836%0.357CS..EExtended strand (participates in β ladder)trans-113.686.2170.7-78-84.1000112.3R251 V254 L255 I262 M269 P270R251-F265 HydrophobicContact CB-CD2 3.77Å; R251-F265 HydrophobicContact CB-CE2 3.83Å; R251-F265 HydrophobicContact CB-CG 4.13Å; R251-F265 HydrophobicContact CB-CZ 4.22Å; R251-F265 HydrophobicContact CG-CD1 3.95Å; R251-F265 HydrophobicContact CG-CD2 4.11Å; R251-F265 HydrophobicContact CG-CE1 3.91Å; R251-F265 HydrophobicContact CG-CE2 4.08Å; R251-F265 HydrophobicContact CG-CG 4.05Å; R251-F265 HydrophobicContact CG-CZ 3.98Å; R251-F265 VanDerWaalsContact O-CE2 3.27Å; R251-F265 WeakPolarHBondContact O-CE2 3.32Å; V254-F265 HydrophobicContact CB-CE2 4.27Å; V254-F265 HydrophobicContact CB-CZ 4.38Å; V254-F265 HydrophobicContact CG1-CE2 4.03Å; V254-F265 HydrophobicContact CG1-CZ 3.93Å; L255-F265 HydrophobicContact CD1-CD2 4.04Å; L255-F265 HydrophobicContact CD2-CD2 3.99Å; L255-F265 HydrophobicContact CD2-CE2 4.1Å; L255-F265 HydrophobicContact CG-CD2 3.93Å; L255-F265 HydrophobicContact CG-CE2 4.04Å; I262-F265 HydrophobicContact CD1-CZ 4.5Å; I262-F265 HydrophobicContact CG2-CD2 4.43Å; I262-F265 HydrophobicContact CG2-CE2 3.96Å; I262-F265 HydrophobicContact CG2-CZ 4.07Å; F265-M269 CarbonylContact C-O 3.42Å; F265-M269 VanDerWaalsContact CA-O 3.24Å; F265-M269 WeakPolarHBondContact CA-O 3.45Å; F265-P270 HydrophobicContact CD1-CB 4.17Å; F265-P270 HydrophobicContact CE1-CB 3.69Å; F265-P270 HydrophobicContact CE1-CG 4.31Å; F265-P270 HydrophobicContact CZ-CB 4.24Å
266L83.3Confident82.1Confident15 Ų1570.1 Ų70.18%0.07937%0.371CS..EExtended strand (participates in β ladder)trans-78.8125.1177-66.3-174.4000110.8G268 M269 V271 V609 N611 F628L266-G268 PolarHBondContact O-N 3.14Å; L266-M269 PolarHBondContact N-O 2.84Å; L266-M269 WeakPolarHBondContact O-CB 3.5Å; L266-M269 PolarHBondContact O-N 3.31Å; L266-V271 HydrophobicContact CB-CG2 3.91Å; L266-V271 HydrophobicContact CD1-CG2 3.87Å; L266-V271 HydrophobicContact CG-CG2 3.74Å; L266-V609 HydrophobicContact CB-CB 4.09Å; L266-V609 HydrophobicContact CB-CG2 4.06Å; L266-V609 HydrophobicContact CD1-CG2 4.15Å; L266-N611 HydrophobicContact CD2-CB 3.7Å; L266-F628 HydrophobicContact CD1-CD2 4.49Å
267S82.9Confident82.4Confident5 Ų567 Ų674%0.03535%0.351CS..THydrogen-bonded Turntrans43.932.7-170.7-58.30000114.3M269 K523 H610S267-M269 VanDerWaalsContact C-N 3.33Å; S267-M269 PolarHBondContact O-N 3.32Å; S267-K523 WeakPolarHBondContact O-CG 3.28Å; S267-H610 PolarHBondContact OG-CD2 2.8Å; S267-H610 PolarHBondContact OG-CE1 2.83Å; S267-H610 VanDerWaalsContact OG-CE1 3.3Å; S267-H610 PolarHBondContact OG-N 3.22Å; S267-H610 PolarHBondContact OG-ND1 2.77Å; S267-H610 PolarHBondContact OG-NE2 3.41Å; S267-H610 VanDerWaalsContact OG-NE2 3.12Å; S267-H610 PolarHBondContact OG-O 2.78Å
268G77.8Confident82.5Confident10 Ų1062.6 Ų62.610%0.10333%0.331CS..THydrogen-bonded Turntrans83.2-4.2-17900000116.1L266L266-G268 PolarHBondContact O-N 3.14Å
269M82.1Confident83.1Confident21 Ų2161.3 Ų61.310%0.10331%0.309CS..EExtended strand (participates in β ladder)trans-87136.7172.3-65.6-55.9-65.300111.5F265 L266 S267 V271 R528 H607 A636F265-M269 CarbonylContact C-O 3.42Å; F265-M269 VanDerWaalsContact CA-O 3.24Å; F265-M269 WeakPolarHBondContact CA-O 3.45Å; L266-M269 PolarHBondContact N-O 2.84Å; L266-M269 WeakPolarHBondContact O-CB 3.5Å; L266-M269 PolarHBondContact O-N 3.31Å; S267-M269 VanDerWaalsContact C-N 3.33Å; S267-M269 PolarHBondContact O-N 3.32Å; M269-V271 PolarHBondContact O-N 3.11Å; M269-R528 PolarHBondContact SD-NH2 2.85Å; M269-H607 WeakPolarHBondContact CG-CE1 3.23Å; M269-A636 HydrophobicContact CE-CB 3.62Å
270P85.1Confident83.6Confident59 Ų5954.3 Ų54.338%0.38327%0.272SS..EExtended strand (participates in β ladder)trans-68.2126.1172.928.2-32.7000110.6I262 F265I262-P270 HydrophobicContact CD1-CB 3.94Å; I262-P270 HydrophobicContact CG1-CB 4.05Å; I262-P270 HydrophobicContact CG2-CB 3.79Å; F265-P270 HydrophobicContact CD1-CB 4.17Å; F265-P270 HydrophobicContact CE1-CB 3.69Å; F265-P270 HydrophobicContact CE1-CG 4.31Å; F265-P270 HydrophobicContact CZ-CB 4.24Å
271V83.6Confident84Confident8 Ų858.3 Ų58.35%0.04829%0.287CS..EExtended strand (participates in β ladder)trans-97.7126.1170.61770000108.3I262 L263 A264 L266 M269 T275 Y277I262-V271 CarbonylContact C-O 3.45Å; I262-V271 WeakPolarHBondContact CA-O 3.35Å; L263-V271 PolarHBondContact N-O 3.29Å; A264-V271 PolarHBondContact O-N 2.84Å; L266-V271 HydrophobicContact CB-CG2 3.91Å; L266-V271 HydrophobicContact CD1-CG2 3.87Å; L266-V271 HydrophobicContact CG-CG2 3.74Å; M269-V271 PolarHBondContact O-N 3.11Å; V271-T275 HydrophobicContact CG1-CG2 4.44Å; V271-Y277 WeakPolarHBondContact CG1-OH 3.1Å
272T85.9Confident84.3Confident37 Ų3756.7 Ų56.723%0.22728%0.278CS..EExtended strand (participates in β ladder)trans-117.7171.8175.270.20000110.4D261 I262 N274 T275D261-T272 HydrophobicContact CB-CG2 4.48Å; D261-T272 VanDerWaalsContact O-CA 3.25Å; D261-T272 WeakPolarHBondContact O-CA 3.25Å; D261-T272 VanDerWaalsContact O-CB 3.27Å; D261-T272 WeakPolarHBondContact O-CB 3.46Å; I262-T272 HydrophobicContact CG1-CG2 4.03Å; T272-N274 PolarHBondContact O-N 3.09Å; T272-N274 PolarHBondContact OG1-N 2.62Å; T272-T275 PolarHBondContact N-OG1 2.93Å; T272-T275 WeakPolarHBondContact O-CB 3.35Å; T272-T275 PolarHBondContact O-N 3.21Å; T272-T275 PolarHBondContact O-OG1 2.87Å
273R80.7Confident84.5Confident184 Ų18459.2 Ų59.269%0.69430%0.299SS*.THydrogen-bonded Turntrans-57-19171-64.1176.5-178.1163.62.8113.5L263L263-R273 HydrophobicContact CD1-CG 4Å; L263-R273 HydrophobicContact CD2-CG 4.37Å; L263-R273 HydrophobicContact CG-CG 4.46Å
274N81.6Confident85Confident130 Ų13063.3 Ų63.370%0.69532%0.317SS*.THydrogen-bonded Turntrans-1002-179.6-63.6-37.1000113.7T272 K276T272-N274 PolarHBondContact O-N 3.09Å; T272-N274 PolarHBondContact OG1-N 2.62Å; N274-K276 PolarHBondContact O-N 3.46Å
275T84.8Confident85.4Confident29 Ų2964.2 Ų64.218%0.17832%0.319CS..  trans-64.2119.4179.2-680000111.2V271 T272 Y277 I630V271-T275 HydrophobicContact CG1-CG2 4.44Å; T272-T275 PolarHBondContact N-OG1 2.93Å; T272-T275 WeakPolarHBondContact O-CB 3.35Å; T272-T275 PolarHBondContact O-N 3.21Å; T272-T275 PolarHBondContact O-OG1 2.87Å; T275-Y277 HydrophobicContact CG2-CD2 4.49Å; T275-Y277 HydrophobicContact CG2-CE2 4.15Å; T275-Y277 WeakPolarHBondContact O-CD2 3.5Å; T275-Y277 PolarHBondContact O-N 3.18Å; T275-Y277 VanDerWaalsContact O-N 3.15Å; T275-I630 HydrophobicContact CG2-CB 4.4Å; T275-I630 HydrophobicContact CG2-CD1 4.33Å; T275-I630 HydrophobicContact CG2-CG2 4.11Å
276K87.4Confident85.8Confident156 Ų15662.8 Ų62.868%0.67831%0.313SS*.  trans-82.891.9-178.6-65.9-179.7-177.4175.40111.1N274 W631N274-K276 PolarHBondContact O-N 3.46Å; K276-W631 HydrophobicContact CB-CB 4.34Å; K276-W631 PolarHBondContact O-N 3.1Å
277Y87.3Confident86.3Confident59 Ų5967.6 Ų67.623%0.23134%0.339CS..BIsolated β-bridgetrans-61.3148.5163.8-65.5-87.1000111V271 T275 I630 A672V271-Y277 WeakPolarHBondContact CG1-OH 3.1Å; T275-Y277 HydrophobicContact CG2-CD2 4.49Å; T275-Y277 HydrophobicContact CG2-CE2 4.15Å; T275-Y277 WeakPolarHBondContact O-CD2 3.5Å; T275-Y277 PolarHBondContact O-N 3.18Å; T275-Y277 VanDerWaalsContact O-N 3.15Å; Y277-I630 HydrophobicContact CD1-CG2 3.45Å; Y277-I630 VanDerWaalsContact CD1-CG2 3.45Å; Y277-I630 HydrophobicContact CE1-CG2 3.64Å; Y277-I630 HydrophobicContact CG-CG2 4.12Å; Y277-A672 HydrophobicContact CD1-CB 3.4Å; Y277-A672 HydrophobicContact CE1-CB 3.64Å; Y277-A672 HydrophobicContact CG-CB 4.02Å
278L88.3Confident86.8Confident16 Ų1671.8 Ų71.88%0.08435%0.353CS..  trans-73.7122.1173-173.672.8000109.2L280 E285 Y289 A629 W631L278-L280 HydrophobicContact CD2-CD2 3.82Å; L278-L280 HydrophobicContact CD2-CG 4.42Å; L278-L280 HydrophobicContact CG-CD2 4.27Å; L278-L280 PolarHBondContact O-N 3.28Å; L278-E285 HydrophobicContact CD1-CB 4.16Å; L278-E285 WeakPolarHBondContact CD1-OE2 3.34Å; L278-Y289 HydrophobicContact CD2-CD2 3.34Å; L278-Y289 HydrophobicContact CD2-CE2 3.97Å; L278-Y289 HydrophobicContact CD2-CG 3.91Å; L278-A629 HydrophobicContact CB-CB 3.91Å; L278-A629 HydrophobicContact CD2-CB 3.82Å; L278-A629 PolarHBondContact N-O 3.34Å; L278-W631 HydrophobicContact CD1-CH2 4.38Å; L278-W631 HydrophobicContact CD1-CZ2 3.47Å; L278-W631 VanDerWaalsContact CD1-CZ2 3.47Å
279D85.2Confident87.6Confident76 Ų7671.3 Ų71.341%0.40635%0.349SS..  trans-84.686.6-177.6-177.525.6000111.1K281 N282 E285D279-K281 PolarHBondContact O-N 2.92Å; D279-K281 VanDerWaalsContact OD1-CB 3.24Å; D279-K281 WeakPolarHBondContact OD1-CB 3.22Å; D279-K281 WeakPolarHBondContact OD1-CG 3.46Å; D279-K281 PolarHBondContact OD1-N 3.04Å; D279-N282 HydrophobicContact CB-CB 4.43Å; D279-N282 VanDerWaalsContact O-CB 3.3Å; D279-N282 WeakPolarHBondContact O-CB 3.17Å; D279-N282 PolarHBondContact O-N 3.12Å; D279-E285 PolarHBondContact N-OE2 3.22Å
280L86.7Confident88.2Confident15 Ų1575.9 Ų75.98%0.07937%0.368CS..THydrogen-bonded Turntrans-64.2-6.4175.9-69.1-179.5000114.3L278 M286 Y289 V662 Y666L278-L280 HydrophobicContact CD2-CD2 3.82Å; L278-L280 HydrophobicContact CD2-CG 4.42Å; L278-L280 HydrophobicContact CG-CD2 4.27Å; L278-L280 PolarHBondContact O-N 3.28Å; L280-M286 HydrophobicContact CB-CE 3.78Å; L280-M286 HydrophobicContact CD2-CE 3.96Å; L280-M286 HydrophobicContact CG-CE 4.3Å; L280-M286 VanDerWaalsContact O-CE 3.3Å; L280-M286 WeakPolarHBondContact O-CE 3.46Å; L280-Y289 HydrophobicContact CD2-CD1 4.19Å; L280-Y289 HydrophobicContact CD2-CG 4.02Å; L280-V662 HydrophobicContact CD1-CG1 3.75Å; L280-Y666 HydrophobicContact CB-CD2 3.48Å; L280-Y666 VanDerWaalsContact CB-CD2 3.48Å; L280-Y666 HydrophobicContact CB-CE2 3.58Å; L280-Y666 HydrophobicContact CB-CG 4.08Å; L280-Y666 HydrophobicContact CD1-CD2 4.18Å; L280-Y666 HydrophobicContact CD1-CG 4.23Å; L280-Y666 HydrophobicContact CG-CD2 4.49Å; L280-Y666 PolarHBondContact O-OH 3.32Å
281K85.3Confident88.7Confident142 Ų14275.2 Ų75.262%0.61736%0.36SS*.THydrogen-bonded Turntrans-76.5-29167.1-56.6175.6179.2177.20112D279 S283 Y666D279-K281 PolarHBondContact O-N 2.92Å; D279-K281 VanDerWaalsContact OD1-CB 3.24Å; D279-K281 WeakPolarHBondContact OD1-CB 3.22Å; D279-K281 WeakPolarHBondContact OD1-CG 3.46Å; D279-K281 PolarHBondContact OD1-N 3.04Å; K281-S283 PolarHBondContact O-N 2.82Å; K281-Y666 HydrophobicContact CG-CE2 4.19Å
282N89.9Confident89.4Confident65 Ų6574.8 Ų74.835%0.34836%0.357SS..SBendtrans-70.5119.2174.4-178-14.9000109.7D279 Q284 E285 M286D279-N282 HydrophobicContact CB-CB 4.43Å; D279-N282 VanDerWaalsContact O-CB 3.3Å; D279-N282 WeakPolarHBondContact O-CB 3.17Å; D279-N282 PolarHBondContact O-N 3.12Å; N282-Q284 PolarHBondContact O-N 3.36Å; N282-Q284 VanDerWaalsContact O-N 3.15Å; N282-Q284 PolarHBondContact OD1-N 3.28Å; N282-E285 HydrophobicContact CB-CB 4.32Å; N282-E285 HydrophobicContact CB-CG 4.2Å; N282-E285 PolarHBondContact O-N 2.88Å; N282-E285 VanDerWaalsContact O-N 3.12Å; N282-M286 WeakPolarHBondContact O-CB 3.33Å; N282-M286 PolarHBondContact O-N 3.26Å
283S90.1Very high89.9Confident95 Ų9573.6 Ų73.666%0.66435%0.35SS*.Hα-helixtrans-58.1-29.6-178.258.60000113.5K281 L287K281-S283 PolarHBondContact O-N 2.82Å; S283-L287 VanDerWaalsContact O-CB 3.32Å; S283-L287 WeakPolarHBondContact O-CB 3.43Å; S283-L287 PolarHBondContact O-N 3.19Å
284Q91.9Very high90.6Very high141 Ų14166.7 Ų66.766%0.65932%0.324SS*.Hα-helixtrans-75.3-39177.4-60.1-172.45.700112.6N282 L287 R288N282-Q284 PolarHBondContact O-N 3.36Å; N282-Q284 VanDerWaalsContact O-N 3.15Å; N282-Q284 PolarHBondContact OD1-N 3.28Å; Q284-L287 PolarHBondContact O-N 2.75Å; Q284-R288 PolarHBondContact O-N 2.97Å
285E89.8Confident91.4Very high33 Ų3360.6 Ų60.615%0.15429%0.292CS..Hα-helixtrans-74-39.6176.9-59.9-141.6127.200111L278 D279 N282 L287 R288 Y289L278-E285 HydrophobicContact CD1-CB 4.16Å; L278-E285 WeakPolarHBondContact CD1-OE2 3.34Å; D279-E285 PolarHBondContact N-OE2 3.22Å; N282-E285 HydrophobicContact CB-CB 4.32Å; N282-E285 HydrophobicContact CB-CG 4.2Å; N282-E285 PolarHBondContact O-N 2.88Å; N282-E285 VanDerWaalsContact O-N 3.12Å; E285-L287 VanDerWaalsContact C-N 3.33Å; E285-L287 PolarHBondContact O-N 3.36Å; E285-R288 PolarHBondContact O-N 3.12Å; E285-R288 IonicContact OE1-NH1 2.75Å; E285-Y289 WeakPolarHBondContact O-CB 3.21Å; E285-Y289 PolarHBondContact O-N 3.04Å
286M92.5Very high92Very high23 Ų2359.2 Ų59.211%0.11328%0.283CS..Hα-helixtrans-57.7-42169.5174.255.365.900112.2L280 N282 Y289 K290 L663 Y666L280-M286 HydrophobicContact CB-CE 3.78Å; L280-M286 HydrophobicContact CD2-CE 3.96Å; L280-M286 HydrophobicContact CG-CE 4.3Å; L280-M286 VanDerWaalsContact O-CE 3.3Å; L280-M286 WeakPolarHBondContact O-CE 3.46Å; N282-M286 WeakPolarHBondContact O-CB 3.33Å; N282-M286 PolarHBondContact O-N 3.26Å; M286-Y289 PolarHBondContact O-N 3.07Å; M286-K290 HydrophobicContact CG-CD 4.39Å; M286-K290 WeakPolarHBondContact O-CB 3.31Å; M286-K290 WeakPolarHBondContact O-CG 3.47Å; M286-K290 PolarHBondContact O-N 2.84Å; M286-K290 HydrophobicContact SD-CD 3.93Å; M286-K290 WeakPolarHBondContact SD-CE 3.29Å; M286-K290 HydrophobicContact SD-CG 4.17Å; M286-L663 HydrophobicContact CE-CD2 4.29Å; M286-L663 HydrophobicContact SD-CD2 4.06Å; M286-Y666 HydrophobicContact CE-CD1 3.82Å; M286-Y666 HydrophobicContact CE-CE1 3.72Å; M286-Y666 HydrophobicContact CE-CG 4.39Å
287L93.8Very high92.3Very high116 Ų11652.7 Ų52.761%0.60726%0.255SS*.Hα-helixtrans-63.5-47.5174.7-169.581.8000111.3S283 Q284 E285 Y289 K290 E291S283-L287 VanDerWaalsContact O-CB 3.32Å; S283-L287 WeakPolarHBondContact O-CB 3.43Å; S283-L287 PolarHBondContact O-N 3.19Å; Q284-L287 PolarHBondContact O-N 2.75Å; E285-L287 VanDerWaalsContact C-N 3.33Å; E285-L287 PolarHBondContact O-N 3.36Å; L287-Y289 VanDerWaalsContact C-N 3.35Å; L287-Y289 PolarHBondContact O-N 2.96Å; L287-K290 PolarHBondContact O-N 3.11Å; L287-E291 PolarHBondContact O-N 3.07Å
288R92.4Very high92.8Very high92 Ų9249.9 Ų49.935%0.34724%0.244SC..Hα-helixtrans-60.2-42.9177.1-176.2-177.3-67.5120.61.3111.6Q284 E285 K290 E291 V292Q284-R288 PolarHBondContact O-N 2.97Å; E285-R288 PolarHBondContact O-N 3.12Å; E285-R288 IonicContact OE1-NH1 2.75Å; R288-K290 VanDerWaalsContact C-N 3.31Å; R288-K290 PolarHBondContact O-N 2.74Å; R288-E291 WeakPolarHBondContact O-CB 3.34Å; R288-E291 PolarHBondContact O-N 3.01Å; R288-V292 WeakPolarHBondContact O-CG2 3.39Å; R288-V292 PolarHBondContact O-N 3.07Å
289Y95.1Very high93.2Very high1 Ų149.1 Ų49.10%0.00424%0.24CC..Hα-helixtrans-66.2-34.6178-160.5-103.5000112L278 L280 E285 M286 L287 V292 C293 I606 A629 L659 V662 L663L278-Y289 HydrophobicContact CD2-CD2 3.34Å; L278-Y289 HydrophobicContact CD2-CE2 3.97Å; L278-Y289 HydrophobicContact CD2-CG 3.91Å; L280-Y289 HydrophobicContact CD2-CD1 4.19Å; L280-Y289 HydrophobicContact CD2-CG 4.02Å; E285-Y289 WeakPolarHBondContact O-CB 3.21Å; E285-Y289 PolarHBondContact O-N 3.04Å; M286-Y289 PolarHBondContact O-N 3.07Å; L287-Y289 VanDerWaalsContact C-N 3.35Å; L287-Y289 PolarHBondContact O-N 2.96Å; Y289-V292 WeakPolarHBondContact O-CB 3.38Å; Y289-V292 PolarHBondContact O-N 3.1Å; Y289-C293 PolarHBondContact O-N 3.26Å; Y289-C293 PolarHBondContact O-SG 2.93Å; Y289-I606 HydrophobicContact CD2-CG2 4.46Å; Y289-I606 HydrophobicContact CE2-CG2 3.99Å; Y289-A629 HydrophobicContact CE2-CB 3.89Å; Y289-L659 HydrophobicContact CE2-CD2 4.07Å; Y289-L659 WeakPolarHBondContact OH-CD2 3.27Å; Y289-V662 HydrophobicContact CE1-CB 4.04Å; Y289-V662 HydrophobicContact CE1-CG1 3.92Å; Y289-V662 VanDerWaalsContact OH-CB 3.28Å; Y289-V662 WeakPolarHBondContact OH-CB 3.43Å; Y289-V662 WeakPolarHBondContact OH-CG2 3.06Å; Y289-L663 HydrophobicContact CD1-CD2 3.85Å; Y289-L663 HydrophobicContact CD1-CG 4.11Å; Y289-L663 HydrophobicContact CE1-CD2 4.23Å; Y289-L663 HydrophobicContact CE1-CG 4.04Å
290K95.4Very high93.6Very high117 Ų11745.7 Ų45.751%0.50922%0.222SC..Hα-helixtrans-68.9-33.9170.6-75.8174.4172.1172.50113.2M286 L287 R288 V292 Y294M286-K290 HydrophobicContact CG-CD 4.39Å; M286-K290 WeakPolarHBondContact O-CB 3.31Å; M286-K290 WeakPolarHBondContact O-CG 3.47Å; M286-K290 PolarHBondContact O-N 2.84Å; M286-K290 HydrophobicContact SD-CD 3.93Å; M286-K290 WeakPolarHBondContact SD-CE 3.29Å; M286-K290 HydrophobicContact SD-CG 4.17Å; L287-K290 PolarHBondContact O-N 3.11Å; R288-K290 VanDerWaalsContact C-N 3.31Å; R288-K290 PolarHBondContact O-N 2.74Å; K290-V292 VanDerWaalsContact C-N 3.35Å; K290-Y294 WeakPolarHBondContact O-CB 3.46Å; K290-Y294 PolarHBondContact O-N 2.81Å
291E95.4Very high94Very high44 Ų4445.2 Ų45.221%0.20622%0.22CC..Hα-helixtrans-60-45.9167.3-68.7-168.7133.600110.5L287 R288 Y294 Y295 K493 F495L287-E291 PolarHBondContact O-N 3.07Å; R288-E291 WeakPolarHBondContact O-CB 3.34Å; R288-E291 PolarHBondContact O-N 3.01Å; E291-Y294 PolarHBondContact O-N 3.05Å; E291-Y295 HydrophobicContact CB-CD2 4.26Å; E291-Y295 HydrophobicContact CB-CE2 4.11Å; E291-Y295 HydrophobicContact CG-CE2 4.48Å; E291-Y295 WeakPolarHBondContact O-CD2 3.24Å; E291-Y295 PolarHBondContact O-N 3.21Å; E291-K493 IonicContact OE1-NZ 3.4Å; E291-K493 PolarHBondContact OE1-NZ 2.83Å; E291-K493 IonicContact OE2-NZ 3.24Å; E291-K493 PolarHBondContact OE2-NZ 3.45Å; E291-F495 HydrophobicContact CB-CE1 4.37Å; E291-F495 HydrophobicContact CB-CZ 4Å
292V96.9Very high94.4Very high0 Ų039 Ų390%020%0.196CC..Hα-helixtrans-62.7-41.4178.61730000112.5R288 Y289 K290 Y294 M296 F495 Y497 T517 V519 I606 L659R288-V292 WeakPolarHBondContact O-CG2 3.39Å; R288-V292 PolarHBondContact O-N 3.07Å; Y289-V292 WeakPolarHBondContact O-CB 3.38Å; Y289-V292 PolarHBondContact O-N 3.1Å; K290-V292 VanDerWaalsContact C-N 3.35Å; V292-Y294 VanDerWaalsContact C-N 3.33Å; V292-Y294 PolarHBondContact O-N 3.21Å; V292-M296 PolarHBondContact O-N 3.4Å; V292-F495 HydrophobicContact CG2-CD1 3.92Å; V292-F495 HydrophobicContact CG2-CE1 3.75Å; V292-Y497 HydrophobicContact CG1-CE1 3.92Å; V292-Y497 PolarHBondContact O-OH 3.34Å; V292-T517 HydrophobicContact CG2-CG2 3.97Å; V292-V519 HydrophobicContact CG1-CG2 3.43Å; V292-V519 VanDerWaalsContact CG1-CG2 3.43Å; V292-I606 HydrophobicContact CG2-CD1 4.14Å; V292-L659 HydrophobicContact CG1-CD1 4.43Å; V292-L659 HydrophobicContact CG1-CD2 4.05Å
293C96.6Very high94.4Very high12 Ų1236.5 Ų36.58%0.08118%0.181CC..Hα-helixtrans-65.8-39174.3-600000111.6Y289Y289-C293 PolarHBondContact O-N 3.26Å; Y289-C293 PolarHBondContact O-SG 2.93Å
294Y96.7Very high94.4Very high39 Ų3932.1 Ų32.115%0.15315%0.152CC..Hα-helixtrans-69.3-47.9-177.1-176.6-100.9000113K290 E291 V292 M296 L297 F298 M363 D387 K390K290-Y294 WeakPolarHBondContact O-CB 3.46Å; K290-Y294 PolarHBondContact O-N 2.81Å; E291-Y294 PolarHBondContact O-N 3.05Å; V292-Y294 VanDerWaalsContact C-N 3.33Å; V292-Y294 PolarHBondContact O-N 3.21Å; Y294-M296 PolarHBondContact O-N 2.68Å; Y294-L297 WeakPolarHBondContact O-CB 3.27Å; Y294-L297 PolarHBondContact O-N 2.97Å; Y294-F298 HydrophobicContact CD1-CE2 4.3Å; Y294-F298 AromaticContact CE1-CE2 3.84Å; Y294-F298 HydrophobicContact CE1-CE2 3.84Å; Y294-M363 HydrophobicContact CE1-CE 4.25Å; Y294-M363 HydrophobicContact CE2-CE 3.71Å; Y294-M363 HydrophobicContact CE2-SD 4.08Å; Y294-M363 WeakPolarHBondContact OH-CE 3.42Å; Y294-D387 WeakPolarHBondContact CE1-OD2 3.25Å; Y294-D387 PolarHBondContact OH-OD2 3.07Å; Y294-K390 HydrophobicContact CD1-CG 4.37Å; Y294-K390 HydrophobicContact CE1-CD 4.23Å; Y294-K390 VanDerWaalsContact CE1-CE 3.5Å; Y294-K390 HydrophobicContact CE1-CG 3.61Å
295Y97.7Very high94.1Very high2 Ų228.1 Ų28.11%0.00813%0.13CC..Hα-helixtrans-72.5-16.5-178.8-66.6-66.2000113.5E291 L297 F298 A299 V394 I467 F495E291-Y295 HydrophobicContact CB-CD2 4.26Å; E291-Y295 HydrophobicContact CB-CE2 4.11Å; E291-Y295 HydrophobicContact CG-CE2 4.48Å; E291-Y295 WeakPolarHBondContact O-CD2 3.24Å; E291-Y295 PolarHBondContact O-N 3.21Å; Y295-L297 PolarHBondContact O-N 3.29Å; Y295-F298 AromaticContact CD1-CD2 3.98Å; Y295-F298 HydrophobicContact CD1-CD2 3.98Å; Y295-F298 HydrophobicContact CD1-CE2 4.06Å; Y295-F298 HydrophobicContact CE1-CE2 4.38Å; Y295-F298 WeakPolarHBondContact O-CB 3.09Å; Y295-F298 PolarHBondContact O-N 2.77Å; Y295-F298 VanDerWaalsContact O-N 3.14Å; Y295-A299 PolarHBondContact O-N 2.88Å; Y295-V394 HydrophobicContact CE1-CG2 4.21Å; Y295-I467 HydrophobicContact CD1-CG2 4.19Å; Y295-I467 HydrophobicContact CE1-CG1 4.23Å; Y295-I467 HydrophobicContact CE1-CG2 4.26Å; Y295-I467 HydrophobicContact CG-CG2 4.5Å; Y295-F495 AromaticContact CD2-CD2 3.52Å; Y295-F495 HydrophobicContact CD2-CD2 3.52Å; Y295-F495 HydrophobicContact CD2-CE1 4.41Å; Y295-F495 AromaticContact CD2-CE2 3.2Å; Y295-F495 HydrophobicContact CD2-CE2 3.2Å; Y295-F495 HydrophobicContact CD2-CG 4.27Å; Y295-F495 AromaticContact CD2-CZ 3.7Å; Y295-F495 HydrophobicContact CD2-CZ 3.7Å; Y295-F495 HydrophobicContact CE2-CD2 4.25Å; Y295-F495 AromaticContact CE2-CE2 3.53Å; Y295-F495 HydrophobicContact CE2-CE2 3.53Å; Y295-F495 HydrophobicContact CE2-CZ 4.01Å; Y295-F495 AromaticContact CG-CD2 3.85Å; Y295-F495 HydrophobicContact CG-CD2 3.85Å; Y295-F495 AromaticContact CG-CE2 3.98Å; Y295-F495 HydrophobicContact CG-CE2 3.98Å
296M96.7Very high93.8Very high0 Ų027.2 Ų27.20%013%0.127CC..Hα-helixtrans-63.7-24.7170.8-173.755.7-171.900112.7V292 Y294 F298 A299 L300 Y497 P652 V655 M656 L659V292-M296 PolarHBondContact O-N 3.4Å; Y294-M296 PolarHBondContact O-N 2.68Å; M296-F298 VanDerWaalsContact C-N 3.34Å; M296-A299 PolarHBondContact O-N 2.78Å; M296-A299 HydrophobicContact SD-CB 3.9Å; M296-L300 VanDerWaalsContact O-CB 3.3Å; M296-L300 WeakPolarHBondContact O-CB 3.47Å; M296-L300 PolarHBondContact O-N 3.18Å; M296-Y497 HydrophobicContact CB-CD1 4.24Å; M296-Y497 HydrophobicContact CB-CE1 3.74Å; M296-Y497 HydrophobicContact CB-CE2 4.17Å; M296-Y497 HydrophobicContact CE-CG 4.47Å; M296-Y497 HydrophobicContact CG-CD1 4.2Å; M296-Y497 HydrophobicContact CG-CE1 4.21Å; M296-Y497 HydrophobicContact CG-CG 4.49Å; M296-Y497 PolarHBondContact N-OH 3.5Å; M296-Y497 HydrophobicContact SD-CD1 3.47Å; M296-Y497 WeakPolarHBondContact SD-CD1 3.3Å; M296-Y497 HydrophobicContact SD-CD2 3.47Å; M296-Y497 WeakPolarHBondContact SD-CD2 3.1Å; M296-Y497 HydrophobicContact SD-CE1 3.96Å; M296-Y497 HydrophobicContact SD-CE2 3.95Å; M296-Y497 HydrophobicContact SD-CG 3.24Å; M296-P652 HydrophobicContact CE-CB 3.7Å; M296-P652 WeakPolarHBondContact CE-O 3.15Å; M296-V655 HydrophobicContact CE-CB 3.99Å; M296-V655 HydrophobicContact CE-CG1 4Å; M296-V655 HydrophobicContact SD-CG1 4.46Å; M296-M656 HydrophobicContact CB-CE 3.61Å; M296-M656 HydrophobicContact CB-SD 4.38Å; M296-M656 HydrophobicContact CG-CB 4.15Å; M296-M656 HydrophobicContact CG-CE 3.71Å; M296-M656 HydrophobicContact CG-SD 4.28Å; M296-L659 HydrophobicContact CB-CD1 4.13Å; M296-L659 HydrophobicContact CG-CD1 4.17Å
297L95.6Very high93.4Very high18 Ų1826.9 Ų26.99%0.09413%0.125CC..Hα-helixtrans-62.9-40.7171.9-67.2169.5000111.7Y294 Y295 L300 A301 H357 E361 M363 M656Y294-L297 WeakPolarHBondContact O-CB 3.27Å; Y294-L297 PolarHBondContact O-N 2.97Å; Y295-L297 PolarHBondContact O-N 3.29Å; L297-L300 PolarHBondContact O-N 3.25Å; L297-A301 WeakPolarHBondContact O-CB 3.45Å; L297-A301 PolarHBondContact O-N 3.17Å; L297-H357 PolarHBondContact O-NE2 3Å; L297-E361 HydrophobicContact CD1-CB 4.38Å; L297-E361 HydrophobicContact CD1-CG 4.28Å; L297-E361 HydrophobicContact CD2-CG 3.92Å; L297-M363 HydrophobicContact CB-SD 4.46Å; L297-M363 HydrophobicContact CD1-SD 3.54Å; L297-M363 VanDerWaalsContact CD1-SD 3.54Å; L297-M656 HydrophobicContact CB-CE 4.42Å; L297-M656 HydrophobicContact CD2-CE 3.49Å; L297-M656 VanDerWaalsContact CD2-CE 3.49Å; L297-M656 HydrophobicContact CG-CE 3.62Å
298F97.1Very high93Very high0 Ų021.9 Ų21.90%010%0.099CC..Hα-helixtrans-64.8-45.5177.2-70.2-102.7000111.2Y294 Y295 M296 L300 A301 A302 F358 M363 V366 Y383 A385 D387 V394 S396 V469Y294-F298 HydrophobicContact CD1-CE2 4.3Å; Y294-F298 AromaticContact CE1-CE2 3.84Å; Y294-F298 HydrophobicContact CE1-CE2 3.84Å; Y295-F298 AromaticContact CD1-CD2 3.98Å; Y295-F298 HydrophobicContact CD1-CD2 3.98Å; Y295-F298 HydrophobicContact CD1-CE2 4.06Å; Y295-F298 HydrophobicContact CE1-CE2 4.38Å; Y295-F298 WeakPolarHBondContact O-CB 3.09Å; Y295-F298 PolarHBondContact O-N 2.77Å; Y295-F298 VanDerWaalsContact O-N 3.14Å; M296-F298 VanDerWaalsContact C-N 3.34Å; F298-L300 VanDerWaalsContact C-N 3.35Å; F298-L300 PolarHBondContact O-N 2.97Å; F298-A301 PolarHBondContact O-N 3.32Å; F298-A302 PolarHBondContact O-N 3.46Å; F298-F358 AromaticContact CD1-CE1 3.91Å; F298-F358 HydrophobicContact CD1-CE1 3.91Å; F298-F358 AromaticContact CD1-CZ 3.54Å; F298-F358 HydrophobicContact CD1-CZ 3.54Å; F298-F358 HydrophobicContact CD2-CE1 4.23Å; F298-F358 AromaticContact CE1-CE1 3.92Å; F298-F358 HydrophobicContact CE1-CE1 3.92Å; F298-F358 AromaticContact CE1-CZ 3.75Å; F298-F358 HydrophobicContact CE1-CZ 3.75Å; F298-F358 HydrophobicContact CE2-CE1 4.26Å; F298-F358 HydrophobicContact CG-CE1 4.07Å; F298-F358 HydrophobicContact CG-CZ 4.02Å; F298-F358 HydrophobicContact CZ-CE1 4.11Å; F298-F358 HydrophobicContact CZ-CZ 4.41Å; F298-M363 HydrophobicContact CD2-CE 4.36Å; F298-M363 HydrophobicContact CE2-CE 3.53Å; F298-M363 HydrophobicContact CZ-CE 3.83Å; F298-V366 HydrophobicContact CE1-CG1 3.89Å; F298-V366 HydrophobicContact CZ-CG1 4.21Å; F298-V366 HydrophobicContact CZ-CG2 4.1Å; F298-Y383 WeakPolarHBondContact CA-OH 3.49Å; F298-Y383 WeakPolarHBondContact CB-OH 3.49Å; F298-Y383 HydrophobicContact CD1-CE2 4.45Å; F298-Y383 PolarHBondContact O-OH 3.48Å; F298-A385 HydrophobicContact CE1-CB 4.4Å; F298-D387 HydrophobicContact CZ-CB 4.36Å; F298-V394 HydrophobicContact CB-CG1 4.29Å; F298-V394 HydrophobicContact CD1-CB 3.98Å; F298-V394 HydrophobicContact CD1-CG1 3.66Å; F298-V394 HydrophobicContact CD1-CG2 4.28Å; F298-V394 HydrophobicContact CE1-CB 3.97Å; F298-V394 HydrophobicContact CE1-CG1 4.13Å; F298-V394 HydrophobicContact CE1-CG2 3.87Å; F298-V394 HydrophobicContact CG-CG1 4.02Å; F298-V394 HydrophobicContact CZ-CG2 4.14Å; F298-S396 PolarHBondContact O-OG 3.23Å; F298-V469 HydrophobicContact CB-CG1 3.84Å
299A96.6Very high92.6Very high0 Ų018.3 Ų18.30%09%0.086CC..Hα-helixtrans-58.5-45175.100000112.3Y295 M296 A302 V469 H471 Y497Y295-A299 PolarHBondContact O-N 2.88Å; M296-A299 PolarHBondContact O-N 2.78Å; M296-A299 HydrophobicContact SD-CB 3.9Å; A299-A302 WeakPolarHBondContact O-CB 3.39Å; A299-A302 PolarHBondContact O-N 3.23Å; A299-V469 HydrophobicContact CB-CG2 4.08Å; A299-H471 HydrophobicContact CB-CB 4.37Å; A299-Y497 HydrophobicContact CB-CD2 3.94Å; A299-Y497 HydrophobicContact CB-CE2 4.27Å
300L94.2Very high92Very high5 Ų522.1 Ų22.13%0.02611%0.105CC..Hα-helixtrans-66.4-36.6179-178.359.1000112.2M296 L297 F298 A302 M307 P652M296-L300 VanDerWaalsContact O-CB 3.3Å; M296-L300 WeakPolarHBondContact O-CB 3.47Å; M296-L300 PolarHBondContact O-N 3.18Å; L297-L300 PolarHBondContact O-N 3.25Å; F298-L300 VanDerWaalsContact C-N 3.35Å; F298-L300 PolarHBondContact O-N 2.97Å; L300-A302 VanDerWaalsContact C-N 3.32Å; L300-A302 PolarHBondContact O-N 3.28Å; L300-M307 HydrophobicContact CD1-CE 3.62Å; L300-P652 HydrophobicContact CD1-CB 4.03Å; L300-P652 HydrophobicContact CD1-CG 4.17Å
301A93.8Very high91.3Very high4 Ų420.9 Ų20.93%0.03310%0.097CC..Hα-helixtrans-66.4-29.9176.700000113.2L297 F298 Y303 G304 I354 H357 F358 Y383L297-A301 WeakPolarHBondContact O-CB 3.45Å; L297-A301 PolarHBondContact O-N 3.17Å; F298-A301 PolarHBondContact O-N 3.32Å; A301-Y303 PolarHBondContact O-N 3.03Å; A301-G304 PolarHBondContact O-N 3.03Å; A301-I354 HydrophobicContact CB-CG2 4.34Å; A301-I354 VanDerWaalsContact O-CG1 3.3Å; A301-I354 WeakPolarHBondContact O-CG1 3.03Å; A301-H357 HydrophobicContact CB-CB 4.29Å; A301-F358 HydrophobicContact CB-CZ 4.3Å; A301-Y383 HydrophobicContact CB-CE1 4.48Å
302A93.9Very high90.6Very high12 Ų1223 Ų2310%0.09911%0.106CC..THydrogen-bonded Turntrans-58.7-23.5-177.600000114.2F298 A299 L300 G304 Y383 R398F298-A302 PolarHBondContact O-N 3.46Å; A299-A302 WeakPolarHBondContact O-CB 3.39Å; A299-A302 PolarHBondContact O-N 3.23Å; L300-A302 VanDerWaalsContact C-N 3.32Å; L300-A302 PolarHBondContact O-N 3.28Å; A302-G304 VanDerWaalsContact C-N 3.26Å; A302-G304 PolarHBondContact O-N 2.63Å; A302-Y383 HydrophobicContact CB-CD1 4.17Å; A302-Y383 HydrophobicContact CB-CE1 3.8Å; A302-R398 HydrophobicContact CB-CB 4.37Å; A302-R398 WeakPolarHBondContact O-CG 3.34Å
303Y90.5Very high89.6Confident12 Ų1227.6 Ų27.65%0.04714%0.136CC..THydrogen-bonded Turntrans-76.1-5.1176.3-72.8-86.1000114.6A301 P306 M307 R398 G399 L401 H471 P652A301-Y303 PolarHBondContact O-N 3.03Å; Y303-P306 WeakPolarHBondContact O-CD 3.27Å; Y303-M307 HydrophobicContact CD1-CG 4.27Å; Y303-M307 HydrophobicContact CD2-CG 4.48Å; Y303-M307 HydrophobicContact CG-CG 3.83Å; Y303-R398 HydrophobicContact CD1-CG 3.89Å; Y303-R398 HydrophobicContact CE1-CG 4.24Å; Y303-R398 HydrophobicContact CG-CG 4.17Å; Y303-G399 WeakPolarHBondContact OH-CA 3.38Å; Y303-L401 HydrophobicContact CD1-CB 4.23Å; Y303-L401 HydrophobicContact CD1-CD1 4.06Å; Y303-L401 HydrophobicContact CD1-CD2 4.23Å; Y303-L401 HydrophobicContact CD1-CG 4.41Å; Y303-L401 HydrophobicContact CE1-CB 4.37Å; Y303-H471 HydrophobicContact CE2-CB 4.17Å; Y303-H471 AromaticContact CZ-ND1 3.9Å; Y303-H471 PolarHBondContact OH-ND1 2.73Å; Y303-P652 HydrophobicContact CD2-CG 4.24Å; Y303-P652 HydrophobicContact CE2-CB 4.22Å; Y303-P652 HydrophobicContact CE2-CG 3.8Å
304G89.6Confident88.7Confident4 Ų431.6 Ų31.64%0.04117%0.169CC..Hα-helixtrans67.2-145.4171.500000114.7A301 A302 Y308A301-G304 PolarHBondContact O-N 3.03Å; A302-G304 VanDerWaalsContact C-N 3.26Å; A302-G304 PolarHBondContact O-N 2.63Å; G304-Y308 PolarHBondContact O-N 3.06Å
305W85.4Confident87.8Confident57 Ų5732.8 Ų32.822%0.21618%0.183CC..Hα-helixtrans-67.9-35-16972.4-93.3000115.9M307 Y308 L309 L320 C349 N350 A353 P906W305-M307 PolarHBondContact O-N 2.73Å; W305-Y308 PolarHBondContact O-N 2.95Å; W305-L309 HydrophobicContact CE3-CD1 3.71Å; W305-L309 HydrophobicContact CE3-CG 4.3Å; W305-L309 HydrophobicContact CZ3-CD1 3.87Å; W305-L309 WeakPolarHBondContact O-CG 3.46Å; W305-L309 PolarHBondContact O-N 3.13Å; W305-L320 HydrophobicContact CB-CD1 3.98Å; W305-C349 HydrophobicContact CB-CB 4.16Å; W305-C349 HydrophobicContact CG-CB 3.99Å; W305-N350 VanDerWaalsContact CD1-OD1 3.26Å; W305-A353 HydrophobicContact CB-CB 3.88Å; W305-P906 HydrophobicContact CZ3-CB 4.14Å
306P83.6Confident86.9Confident13 Ų1332.7 Ų32.78%0.08418%0.182CC..Hα-helixtrans-63.1-46.7-178.3-22.734.9000111.9Y303 Y308 L309 M310 V910Y303-P306 WeakPolarHBondContact O-CD 3.27Å; P306-Y308 VanDerWaalsContact C-N 3.35Å; P306-Y308 PolarHBondContact O-N 3.13Å; P306-L309 PolarHBondContact O-N 3Å; P306-M310 WeakPolarHBondContact O-CG 3.49Å; P306-M310 PolarHBondContact O-N 3.09Å; P306-V910 HydrophobicContact CB-CG1 4.33Å
307M84.4Confident86Confident16 Ų1636.8 Ų36.88%0.07920%0.204CC..Hα-helixtrans-68-32.4177.6-81.5-58.4-50.600113.1L300 Y303 W305 M310 R311 P652 Y653L300-M307 HydrophobicContact CD1-CE 3.62Å; Y303-M307 HydrophobicContact CD1-CG 4.27Å; Y303-M307 HydrophobicContact CD2-CG 4.48Å; Y303-M307 HydrophobicContact CG-CG 3.83Å; W305-M307 PolarHBondContact O-N 2.73Å; M307-M310 HydrophobicContact SD-SD 3.9Å; M307-R311 WeakPolarHBondContact O-CB 3.47Å; M307-R311 PolarHBondContact O-N 2.98Å; M307-R311 VanDerWaalsContact O-N 3.14Å; M307-P652 HydrophobicContact CE-CG 4.06Å; M307-P652 HydrophobicContact SD-CG 4.47Å; M307-Y653 HydrophobicContact CE-CD1 3.97Å
308Y84.9Confident85.1Confident11 Ų1140 Ų404%0.04323%0.227CC..Hα-helixtrans-63.2-42171.3-176.9-92.1000111.6G304 W305 P306 K312 Q319 L320 R356 H357 D360G304-Y308 PolarHBondContact O-N 3.06Å; W305-Y308 PolarHBondContact O-N 2.95Å; P306-Y308 VanDerWaalsContact C-N 3.35Å; P306-Y308 PolarHBondContact O-N 3.13Å; Y308-K312 PolarHBondContact O-N 3.08Å; Y308-Q319 PolarHBondContact OH-OE1 3.02Å; Y308-Q319 VanDerWaalsContact OH-OE1 3.08Å; Y308-L320 HydrophobicContact CD1-CD1 3.86Å; Y308-L320 HydrophobicContact CD1-CD2 3.94Å; Y308-L320 HydrophobicContact CD1-CG 3.78Å; Y308-L320 HydrophobicContact CE1-CD1 4.4Å; Y308-L320 HydrophobicContact CE1-CD2 4.05Å; Y308-L320 HydrophobicContact CE1-CG 3.84Å; Y308-R356 HydrophobicContact CE1-CG 4.28Å; Y308-R356 HydrophobicContact CE2-CB 4.27Å; Y308-R356 HydrophobicContact CE2-CG 3.83Å; Y308-R356 VanDerWaalsContact OH-CG 3.24Å; Y308-R356 WeakPolarHBondContact OH-CG 3.37Å; Y308-H357 HydrophobicContact CD2-CB 4.47Å; Y308-D360 WeakPolarHBondContact CE2-OD2 3.39Å; Y308-D360 PolarHBondContact OH-OD2 2.78Å
309L85.2Confident84.2Confident17 Ų1742.8 Ų42.89%0.08924%0.24CC..Hα-helixtrans-67.4-45.6175.9-68.5-171.4000112.7W305 P306 R311 K312 P313 L317 L320 P906W305-L309 HydrophobicContact CE3-CD1 3.71Å; W305-L309 HydrophobicContact CE3-CG 4.3Å; W305-L309 HydrophobicContact CZ3-CD1 3.87Å; W305-L309 WeakPolarHBondContact O-CG 3.46Å; W305-L309 PolarHBondContact O-N 3.13Å; P306-L309 PolarHBondContact O-N 3Å; L309-R311 PolarHBondContact O-N 3.49Å; L309-K312 CarbonylContact O-C 3.43Å; L309-K312 PolarHBondContact O-N 3.29Å; L309-P313 WeakPolarHBondContact O-CA 3.15Å; L309-P313 VanDerWaalsContact O-N 3.12Å; L309-L317 HydrophobicContact CD1-CD2 3.66Å; L309-L317 HydrophobicContact CD1-CG 4.07Å; L309-L317 HydrophobicContact CD2-CB 4.41Å; L309-L317 HydrophobicContact CD2-CD2 4.07Å; L309-L317 HydrophobicContact CD2-CG 3.84Å; L309-L317 VanDerWaalsContact CD2-N 3.28Å; L309-L320 HydrophobicContact CD2-CD1 3.87Å; L309-L320 HydrophobicContact CG-CD1 4.22Å; L309-P906 HydrophobicContact CD1-CB 4.09Å
310M81Confident83.3Confident81 Ų8143.5 Ų43.540%0.39924%0.244SC..Hα-helixtrans-57.3-36.5177.3-70.6175.973.500112.3P306 M307P306-M310 WeakPolarHBondContact O-CG 3.49Å; P306-M310 PolarHBondContact O-N 3.09Å; M307-M310 HydrophobicContact SD-SD 3.9Å
311R81.1Confident82.2Confident92 Ų9246.4 Ų46.435%0.34727%0.268SS..Hα-helixtrans-79.4-17.5176.9-172170.4175.4-123.6-3.1114M307 L309 E361M307-R311 WeakPolarHBondContact O-CB 3.47Å; M307-R311 PolarHBondContact O-N 2.98Å; M307-R311 VanDerWaalsContact O-N 3.14Å; L309-R311 PolarHBondContact O-N 3.49Å; R311-E361 IonicContact CZ-OE1 2.7Å; R311-E361 IonicContact NH1-OE1 3.47Å; R311-E361 PolarHBondContact NH1-OE1 2.91Å; R311-E361 IonicContact NH2-OE1 2.78Å; R311-E361 PolarHBondContact NH2-OE1 3.03Å
312K81.8Confident81Confident89 Ų8957.4 Ų57.439%0.38731%0.309SS..  trans-137.455.7-176.8-63.4-66.9-177-179.50112.2Y308 L309 A314 C315 G316Y308-K312 PolarHBondContact O-N 3.08Å; L309-K312 CarbonylContact O-C 3.43Å; L309-K312 PolarHBondContact O-N 3.29Å; K312-A314 VanDerWaalsContact C-N 3.33Å; K312-A314 PolarHBondContact O-N 2.96Å; K312-C315 PolarHBondContact O-N 2.8Å; K312-G316 WeakPolarHBondContact O-CA 3.42Å; K312-G316 PolarHBondContact O-N 3.16Å
313P76.1Confident79.7Confident96 Ų9659.2 Ų59.262%0.62332%0.321SS*.THydrogen-bonded Turntrans-60.3-38-169.222.8-34000113.7L309 C315L309-P313 WeakPolarHBondContact O-CA 3.15Å; L309-P313 VanDerWaalsContact O-N 3.12Å; P313-C315 PolarHBondContact O-N 3.3Å
314A77.4Confident78.3Confident95 Ų9559.9 Ų59.979%0.78533%0.327SS*.THydrogen-bonded Turntrans-69.7-24.1-17500000115.3K312K312-A314 VanDerWaalsContact C-N 3.33Å; K312-A314 PolarHBondContact O-N 2.96Å
315C77.4Confident76.7Confident64 Ų6461.7 Ų61.743%0.43234%0.339SS..THydrogen-bonded Turntrans-145.9-6.8-172.2-79.80000115.1K312 P313 L317 C318 Q319K312-C315 PolarHBondContact O-N 2.8Å; P313-C315 PolarHBondContact O-N 3.3Å; C315-L317 VanDerWaalsContact C-N 3.3Å; C315-L317 PolarHBondContact O-N 2.78Å; C315-C318 WeakPolarHBondContact O-CB 3.44Å; C315-C318 PolarHBondContact O-N 3.47Å; C315-C318 VanDerWaalsContact O-N 3.08Å; C315-Q319 WeakPolarHBondContact O-CG 3.41Å; C315-Q319 PolarHBondContact O-N 3.2Å
316G78.8Confident74.9Confident0 Ų062.2 Ų62.20%035%0.351CS..Hα-helixtrans-59.3-40-174.700000112.7K312 C318 Q319 L320K312-G316 WeakPolarHBondContact O-CA 3.42Å; K312-G316 PolarHBondContact O-N 3.16Å; G316-C318 PolarHBondContact O-N 3.4Å; G316-Q319 PolarHBondContact O-N 3.4Å; G316-L320 WeakPolarHBondContact O-CB 3.46Å; G316-L320 WeakPolarHBondContact O-CG 3.32Å; G316-L320 PolarHBondContact O-N 3.43Å
317L77.1Confident73.1Confident86 Ų8666.9 Ų66.945%0.4538%0.382SS..Hα-helixtrans-58.5-47174-77.1166.2000111.6L309 C315 Q319 L320 A321L309-L317 HydrophobicContact CD1-CD2 3.66Å; L309-L317 HydrophobicContact CD1-CG 4.07Å; L309-L317 HydrophobicContact CD2-CB 4.41Å; L309-L317 HydrophobicContact CD2-CD2 4.07Å; L309-L317 HydrophobicContact CD2-CG 3.84Å; L309-L317 VanDerWaalsContact CD2-N 3.28Å; C315-L317 VanDerWaalsContact C-N 3.3Å; C315-L317 PolarHBondContact O-N 2.78Å; L317-Q319 VanDerWaalsContact C-N 3.31Å; L317-Q319 PolarHBondContact O-N 3.35Å; L317-L320 PolarHBondContact O-N 2.77Å; L317-A321 WeakPolarHBondContact O-CB 3.06Å; L317-A321 PolarHBondContact O-N 2.83Å
318C77.4Confident71.1Confident86 Ų8674.3 Ų74.358%0.58142%0.422SS*.Hα-helixtrans-64.6-36179.4-53.40000112.3C315 G316 R322C315-C318 WeakPolarHBondContact O-CB 3.44Å; C315-C318 PolarHBondContact O-N 3.47Å; C315-C318 VanDerWaalsContact O-N 3.08Å; G316-C318 PolarHBondContact O-N 3.4Å; C318-R322 VanDerWaalsContact O-CB 3.3Å; C318-R322 WeakPolarHBondContact O-CB 3.39Å; C318-R322 PolarHBondContact O-N 3.46Å
319Q78.3Confident69.2Low58 Ų5877.5 Ų77.527%0.27145%0.445SS..Hα-helixtrans-78-35.8-178.7-65.4-17925.100112.7Y308 C315 G316 L317 S323Y308-Q319 PolarHBondContact OH-OE1 3.02Å; Y308-Q319 VanDerWaalsContact OH-OE1 3.08Å; C315-Q319 WeakPolarHBondContact O-CG 3.41Å; C315-Q319 PolarHBondContact O-N 3.2Å; G316-Q319 PolarHBondContact O-N 3.4Å; L317-Q319 VanDerWaalsContact C-N 3.31Å; L317-Q319 PolarHBondContact O-N 3.35Å; Q319-S323 PolarHBondContact O-N 3.06Å; Q319-S323 PolarHBondContact O-OG 3.48Å
320L77.2Confident67.2Low16 Ų1683.4 Ų83.48%0.08448%0.484CS..Hα-helixtrans-66.5-48.3167.6-70.2179000110.7W305 Y308 L309 G316 L317 R322 S323 C324 I352 A353 R356W305-L320 HydrophobicContact CB-CD1 3.98Å; Y308-L320 HydrophobicContact CD1-CD1 3.86Å; Y308-L320 HydrophobicContact CD1-CD2 3.94Å; Y308-L320 HydrophobicContact CD1-CG 3.78Å; Y308-L320 HydrophobicContact CE1-CD1 4.4Å; Y308-L320 HydrophobicContact CE1-CD2 4.05Å; Y308-L320 HydrophobicContact CE1-CG 3.84Å; L309-L320 HydrophobicContact CD2-CD1 3.87Å; L309-L320 HydrophobicContact CG-CD1 4.22Å; G316-L320 WeakPolarHBondContact O-CB 3.46Å; G316-L320 WeakPolarHBondContact O-CG 3.32Å; G316-L320 PolarHBondContact O-N 3.43Å; L317-L320 PolarHBondContact O-N 2.77Å; L320-R322 VanDerWaalsContact C-N 3.35Å; L320-R322 PolarHBondContact O-N 3.45Å; L320-S323 CarbonylContact O-C 3.28Å; L320-S323 WeakPolarHBondContact O-CA 3.06Å; L320-S323 WeakPolarHBondContact O-CB 3.41Å; L320-S323 PolarHBondContact O-N 2.95Å; L320-C324 WeakPolarHBondContact O-CB 3.32Å; L320-C324 PolarHBondContact O-N 3.17Å; L320-I352 HydrophobicContact CD2-CG2 4.07Å; L320-A353 HydrophobicContact CD2-CB 3.94Å; L320-R356 HydrophobicContact CD2-CB 4.45Å
321A70.7Confident65.6Low66 Ų6682.5 Ų82.555%0.54549%0.489SS..Hα-helixtrans-58.3-42.4179.200000112.6L317 S323 C324L317-A321 WeakPolarHBondContact O-CB 3.06Å; L317-A321 PolarHBondContact O-N 2.83Å; A321-S323 PolarHBondContact O-N 2.88Å; A321-C324 PolarHBondContact O-N 3.08Å; A321-C324 VanDerWaalsContact O-N 3.1Å
322R69.8Low64.1Low235 Ų23588.8 Ų88.889%0.88751%0.513SS*.Hα-helixtrans-62.5-22.2173.6-175.3174.9177.3121.4-0.3113.5C318 L320C318-R322 VanDerWaalsContact O-CB 3.3Å; C318-R322 WeakPolarHBondContact O-CB 3.39Å; C318-R322 PolarHBondContact O-N 3.46Å; L320-R322 VanDerWaalsContact C-N 3.35Å; L320-R322 PolarHBondContact O-N 3.45Å
323S66.3Low62.6Low50 Ų5086.6 Ų86.635%0.3551%0.508SS..Hα-helixtrans-98.3-7.8177.9-50.60000113Q319 L320 A321Q319-S323 PolarHBondContact O-N 3.06Å; Q319-S323 PolarHBondContact O-OG 3.48Å; L320-S323 CarbonylContact O-C 3.28Å; L320-S323 WeakPolarHBondContact O-CA 3.06Å; L320-S323 WeakPolarHBondContact O-CB 3.41Å; L320-S323 PolarHBondContact O-N 2.95Å; A321-S323 PolarHBondContact O-N 2.88Å
324C61.6Low61.4Low25 Ų2593 Ų9317%0.16952%0.519CS..  trans-114.8109.7-166.6177.30000111.2L320 A321 C326 I352L320-C324 WeakPolarHBondContact O-CB 3.32Å; L320-C324 PolarHBondContact O-N 3.17Å; A321-C324 PolarHBondContact O-N 3.08Å; A321-C324 VanDerWaalsContact O-N 3.1Å; C324-C326 VanDerWaalsContact C-N 3.31Å; C324-C326 PolarHBondContact O-N 2.96Å; C324-I352 HydrophobicContact CB-CD1 4.15Å
325S55.3Low60.5Low42 Ų4290.6 Ų90.629%0.29449%0.491SS..  trans-80.378.1173.6-50.30000111A331S325-A331 WeakPolarHBondContact CB-O 3.4Å; S325-A331 PolarHBondContact OG-O 2.81Å
326C47.6Very low59.5Low69 Ų6989.7 Ų89.747%0.46649%0.489SS..  trans-61.9163.1172.7-171.70000111.6C324 L328 C329C324-C326 VanDerWaalsContact C-N 3.31Å; C324-C326 PolarHBondContact O-N 2.96Å; C326-L328 PolarHBondContact O-N 2.97Å; C326-C329 PolarHBondContact O-N 3.27Å
327C45.3Very low58.2Low110 Ų11095.4 Ų95.474%0.74353%0.525SS*.THydrogen-bonded Turntrans-54.9-2.6-163.4-54.70000118.4
328L44.2Very low57.4Low173 Ų17393.6 Ų93.691%0.90653%0.528SS*.THydrogen-bonded Turntrans-96.6-6174.4-70.8163.5000113.3C326C326-L328 PolarHBondContact O-N 2.97Å
329C43.1Very low57.2Low78 Ų7890.9 Ų90.953%0.52751%0.508SS..  trans-109.6121.6178.1-71.80000111.4C326 A331C326-C329 PolarHBondContact O-N 3.27Å; C329-A331 PolarHBondContact O-N 3.3Å; C329-A331 VanDerWaalsContact O-N 3.15Å
330P44.6Very low57.3Low141 Ų14190.5 Ų90.592%0.91651%0.51SS*.SBendtrans-73-5.2-176.529.1-35.6000114.7
331A47.2Very low57.5Low61 Ų6192.6 Ų92.650%0.50452%0.521SS..SBendtrans-96.4101.5177.200000110.9S325 C329S325-A331 WeakPolarHBondContact CB-O 3.4Å; S325-A331 PolarHBondContact OG-O 2.81Å; C329-A331 PolarHBondContact O-N 3.3Å; C329-A331 VanDerWaalsContact O-N 3.15Å
332R49.4Very low57.9Low224 Ų22491.7 Ų91.785%0.84551%0.505SS*.  trans-51.6147.5167.7-76-174.3176.3-173.8-1.4110.9R334R332-R334 PolarHBondContact O-N 3.34Å; R332-R334 VanDerWaalsContact O-N 3.09Å
333P50.7Low57.9Low43 Ų4386.7 Ų86.728%0.27949%0.492SS..  trans-60.1117.2174.826.5-33.9000109.4F335 I352P333-F335 VanDerWaalsContact C-N 3.33Å; P333-F335 HydrophobicContact CB-CE2 4.31Å; P333-F335 HydrophobicContact CG-CE2 4.18Å; P333-F335 PolarHBondContact O-N 3.08Å; P333-I352 HydrophobicContact CB-CD1 4.42Å; P333-I352 HydrophobicContact CG-CD1 4.37Å
334R50.8Low58.4Low231 Ų23185.5 Ų85.587%0.87248%0.482SS*.  trans-75.986.3178-62.6-172.8-167.1175.64.6109.6R332R332-R334 PolarHBondContact O-N 3.34Å; R332-R334 VanDerWaalsContact O-N 3.09Å
335F58.2Low58.8Low44 Ų4487.3 Ų87.319%0.19349%0.49CS..PPolyproline II helixtrans-59.6155.1152.4-69.4-89.1000109.1P333 V339 I341 A351 I352P333-F335 VanDerWaalsContact C-N 3.33Å; P333-F335 HydrophobicContact CB-CE2 4.31Å; P333-F335 HydrophobicContact CG-CE2 4.18Å; P333-F335 PolarHBondContact O-N 3.08Å; F335-V339 HydrophobicContact CB-CB 4.19Å; F335-V339 HydrophobicContact CB-CG2 4.34Å; F335-V339 HydrophobicContact CD1-CG1 4.39Å; F335-I341 HydrophobicContact CD1-CD1 4.19Å; F335-I341 HydrophobicContact CD2-CD1 3.78Å; F335-I341 HydrophobicContact CE1-CD1 4.08Å; F335-I341 HydrophobicContact CE2-CD1 3.66Å; F335-I341 HydrophobicContact CG-CD1 4.05Å; F335-I341 HydrophobicContact CZ-CD1 3.82Å; F335-A351 HydrophobicContact CE1-CB 3.95Å; F335-A351 HydrophobicContact CE2-CB 4.48Å; F335-A351 HydrophobicContact CZ-CB 3.6Å; F335-I352 HydrophobicContact CE2-CG1 4.36Å; F335-I352 HydrophobicContact CZ-CG1 3.95Å
336A55.2Low59.4Low46 Ų4691 Ų9138%0.3851%0.514SS..PPolyproline II helixtrans-60.5151.5175.600000110.3G338 V339A336-G338 PolarHBondContact O-N 3.46Å; A336-V339 HydrophobicContact CB-CG2 4.3Å; A336-V339 WeakPolarHBondContact O-CG2 3Å; A336-V339 PolarHBondContact O-N 3.4Å
337P52.3Low60.3Low119 Ų11988.8 Ų88.877%0.77350%0.499SS*.THydrogen-bonded Turntrans-55.2137.7173.722.4-32.5000110.8R455P337-R455 PolarHBondContact O-NH1 3.07Å; P337-R455 PolarHBondContact O-NH2 3.41Å; P337-R455 VanDerWaalsContact O-NH2 3.15Å
338G61.1Low61.5Low48 Ų4884.2 Ų84.250%0.49547%0.471SS..THydrogen-bonded Turntrans71.832.4-177.600000115.4A336 R455A336-G338 PolarHBondContact O-N 3.46Å; G338-R455 PolarHBondContact O-NH1 3.13Å
339V73.5Confident63.2Low29 Ų2977.2 Ų77.218%0.17644%0.436CS..  trans-96.7121.3156.8-175.20000107.9F335 A336 I341 I368 V369F335-V339 HydrophobicContact CB-CB 4.19Å; F335-V339 HydrophobicContact CB-CG2 4.34Å; F335-V339 HydrophobicContact CD1-CG1 4.39Å; A336-V339 HydrophobicContact CB-CG2 4.3Å; A336-V339 WeakPolarHBondContact O-CG2 3Å; A336-V339 PolarHBondContact O-N 3.4Å; V339-I341 HydrophobicContact CG1-CG1 4.21Å; V339-I368 HydrophobicContact CG1-CG2 4.36Å; V339-I368 VanDerWaalsContact CG2-O 3.26Å; V339-I368 WeakPolarHBondContact CG2-O 3.43Å; V339-V369 WeakPolarHBondContact CA-O 3.16Å
340T79.3Confident65.2Low51 Ų5175 Ų7531%0.31342%0.419SS..EExtended strand (participates in β ladder)trans-98123.7-179.1-59.80000109.5V369 Y370 T371T340-V369 PolarHBondContact N-O 3.48Å; T340-Y370 HydrophobicContact CG2-CD2 3.9Å; T340-Y370 HydrophobicContact CG2-CE2 3.78Å; T340-Y370 CarbonylContact O-C 3.45Å; T340-Y370 WeakPolarHBondContact O-CA 3.45Å; T340-T371 PolarHBondContact O-N 3.24Å
341I81.9Confident67.1Low59 Ų5968.4 Ų68.430%0.30338%0.376SS..EExtended strand (participates in β ladder)trans-124.4117.8-179.3-57.1169.5000108.2F335 V339 D344 A351 T371F335-I341 HydrophobicContact CD1-CD1 4.19Å; F335-I341 HydrophobicContact CD2-CD1 3.78Å; F335-I341 HydrophobicContact CE1-CD1 4.08Å; F335-I341 HydrophobicContact CE2-CD1 3.66Å; F335-I341 HydrophobicContact CG-CD1 4.05Å; F335-I341 HydrophobicContact CZ-CD1 3.82Å; V339-I341 HydrophobicContact CG1-CG1 4.21Å; I341-D344 HydrophobicContact CG2-CB 3.62Å; I341-A351 HydrophobicContact CD1-CB 3.66Å; I341-A351 HydrophobicContact CG1-CB 4.19Å; I341-A351 HydrophobicContact CG2-CB 4.31Å; I341-T371 CarbonylContact C-O 3.6Å; I341-T371 WeakPolarHBondContact CA-O 3.25Å
342E78.9Confident68.9Low48 Ų4866 Ų6622%0.22436%0.355CS..EExtended strand (participates in β ladder)trans-106.2131.4178175.1176.5-124.400110.5D344 Y370 T371 S372 C373 K442E342-D344 PolarHBondContact O-N 2.85Å; E342-Y370 PolarHBondContact OE2-OH 3.48Å; E342-T371 PolarHBondContact N-O 2.85Å; E342-S372 VanDerWaalsContact OE2-CB 3.31Å; E342-S372 WeakPolarHBondContact OE2-CB 3.27Å; E342-S372 PolarHBondContact OE2-OG 3.3Å; E342-C373 PolarHBondContact O-N 2.03Å; E342-K442 IonicContact OE1-NZ 3.27Å; E342-K442 PolarHBondContact OE1-NZ 3.09Å; E342-K442 IonicContact OE2-NZ 3.96Å; E342-K442 PolarHBondContact OE2-NZ 3.36Å
343E70.5Confident70.7Confident129 Ų12955.4 Ų55.460%0.60332%0.315SS*.SBendtrans49.923.7172.1-64.1-165.1-171.200117.7H374E343-H374 VanDerWaalsContact CD-ND1 3.33Å; E343-H374 IonicContact OE1-ND1 2.7Å; E343-H374 IonicContact OE2-CE1 2.73Å; E343-H374 IonicContact OE2-CG 2.75Å; E343-H374 IonicContact OE2-ND1 2.72Å; E343-H374 PolarHBondContact OE2-ND1 2.99Å
344D75.6Confident72.6Confident26 Ų2653.6 Ų53.614%0.13930%0.303CS..  trans-65.4160.6165.9-159.1-4.8000110.7I341 E342 G348 N350 A351 C373I341-D344 HydrophobicContact CG2-CB 3.62Å; E342-D344 PolarHBondContact O-N 2.85Å; D344-G348 VanDerWaalsContact OD2-CA 3.32Å; D344-G348 WeakPolarHBondContact OD2-CA 3.33Å; D344-N350 WeakPolarHBondContact OD1-CB 3.46Å; D344-N350 PolarHBondContact OD1-N 3.24Å; D344-N350 PolarHBondContact OD1-ND2 3.15Å; D344-N350 PolarHBondContact OD2-N 2.87Å; D344-N350 VanDerWaalsContact OD2-N 3.08Å; D344-A351 PolarHBondContact OD2-N 3.37Å; D344-C373 HydrophobicContact CB-CB 4.4Å
345N71.1Confident74.5Confident63 Ų6348.9 Ų48.934%0.33729%0.285SS..  trans-64.8169.5-177.47718.5000112.3C347 G348 C349N345-C347 PolarHBondContact O-N 3.21Å; N345-C347 WeakPolarHBondContact OD1-CA 3.24Å; N345-C347 PolarHBondContact OD1-N 2.83Å; N345-G348 PolarHBondContact O-N 2.97Å; N345-G348 PolarHBondContact OD1-N 3.38Å; N345-C349 WeakPolarHBondContact ND2-CB 3.25Å; N345-C349 PolarHBondContact ND2-SG 2.97Å; N345-C349 PolarHBondContact OD1-N 2.97Å
346C66.9Low75.9Confident120 Ų12049 Ų4981%0.81128%0.284SS*.THydrogen-bonded Turntrans-55.6-14-176.860.20000115.7
347C65.8Low77.6Confident22 Ų2247.2 Ų47.215%0.14927%0.268CS..THydrogen-bonded Turntrans-111.6-3.6-179-74.30000113.6N345 C349 I352N345-C347 PolarHBondContact O-N 3.21Å; N345-C347 WeakPolarHBondContact OD1-CA 3.24Å; N345-C347 PolarHBondContact OD1-N 2.83Å; C347-C349 VanDerWaalsContact C-N 3.33Å; C347-C349 VanDerWaalsContact CB-SG 3.52Å; C347-I352 WeakPolarHBondContact O-CD1 3.36Å
348G71.9Confident79.5Confident14 Ų1441.8 Ų41.814%0.14423%0.232CC..  trans67.327.8-175.800000114.1D344 N345 N350 A351 I352D344-G348 VanDerWaalsContact OD2-CA 3.32Å; D344-G348 WeakPolarHBondContact OD2-CA 3.33Å; N345-G348 PolarHBondContact O-N 2.97Å; N345-G348 PolarHBondContact OD1-N 3.38Å; G348-N350 VanDerWaalsContact C-N 3.31Å; G348-N350 PolarHBondContact O-N 3.35Å; G348-A351 PolarHBondContact O-N 2.82Å; G348-I352 WeakPolarHBondContact O-CB 3.49Å; G348-I352 WeakPolarHBondContact O-CD1 3.21Å; G348-I352 WeakPolarHBondContact O-CG1 3.35Å; G348-I352 PolarHBondContact O-N 3.36Å
349C79.8Confident80.8Confident26 Ų2643 Ų4318%0.17623%0.227CC..Hα-helixtrans-64.7-30-167.4-62.70000113.9W305 N345 C347 A353W305-C349 HydrophobicContact CB-CB 4.16Å; W305-C349 HydrophobicContact CG-CB 3.99Å; N345-C349 WeakPolarHBondContact ND2-CB 3.25Å; N345-C349 PolarHBondContact ND2-SG 2.97Å; N345-C349 PolarHBondContact OD1-N 2.97Å; C347-C349 VanDerWaalsContact C-N 3.33Å; C347-C349 VanDerWaalsContact CB-SG 3.52Å; C349-A353 WeakPolarHBondContact O-CB 3.48Å; C349-A353 PolarHBondContact O-N 3.26Å
350N83.7Confident81.5Confident32 Ų3244 Ų4417%0.17123%0.231CC..Hα-helixtrans-73.6-49.3-179.6-64.8-64.6000110.8W305 D344 G348 I352 A353 I354W305-N350 VanDerWaalsContact CD1-OD1 3.26Å; D344-N350 WeakPolarHBondContact OD1-CB 3.46Å; D344-N350 PolarHBondContact OD1-N 3.24Å; D344-N350 PolarHBondContact OD1-ND2 3.15Å; D344-N350 PolarHBondContact OD2-N 2.87Å; D344-N350 VanDerWaalsContact OD2-N 3.08Å; G348-N350 VanDerWaalsContact C-N 3.31Å; G348-N350 PolarHBondContact O-N 3.35Å; N350-I352 VanDerWaalsContact C-N 3.29Å; N350-I352 PolarHBondContact O-N 3.33Å; N350-A353 PolarHBondContact O-N 2.91Å; N350-A353 VanDerWaalsContact O-N 3.12Å; N350-I354 VanDerWaalsContact O-CG1 3.3Å; N350-I354 WeakPolarHBondContact O-CG1 3.21Å; N350-I354 PolarHBondContact O-N 3.43Å
351A84.6Confident82Confident1 Ų144.5 Ų44.51%0.00823%0.23CC..Hα-helixtrans-62.6-36.5175.600000112.1F335 I341 D344 G348 R355F335-A351 HydrophobicContact CE1-CB 3.95Å; F335-A351 HydrophobicContact CE2-CB 4.48Å; F335-A351 HydrophobicContact CZ-CB 3.6Å; I341-A351 HydrophobicContact CD1-CB 3.66Å; I341-A351 HydrophobicContact CG1-CB 4.19Å; I341-A351 HydrophobicContact CG2-CB 4.31Å; D344-A351 PolarHBondContact OD2-N 3.37Å; G348-A351 PolarHBondContact O-N 2.82Å; A351-R355 WeakPolarHBondContact O-CB 3.21Å; A351-R355 PolarHBondContact O-N 3.37Å; A351-R355 VanDerWaalsContact O-N 3.1Å
352I84.9Confident82.4Confident11 Ų1148.3 Ų48.36%0.05625%0.251CS..Hα-helixtrans-64.8-43.8172.2-70168000111L320 C324 P333 F335 C347 G348 N350 R355 R356L320-I352 HydrophobicContact CD2-CG2 4.07Å; C324-I352 HydrophobicContact CB-CD1 4.15Å; P333-I352 HydrophobicContact CB-CD1 4.42Å; P333-I352 HydrophobicContact CG-CD1 4.37Å; F335-I352 HydrophobicContact CE2-CG1 4.36Å; F335-I352 HydrophobicContact CZ-CG1 3.95Å; C347-I352 WeakPolarHBondContact O-CD1 3.36Å; G348-I352 WeakPolarHBondContact O-CB 3.49Å; G348-I352 WeakPolarHBondContact O-CD1 3.21Å; G348-I352 WeakPolarHBondContact O-CG1 3.35Å; G348-I352 PolarHBondContact O-N 3.36Å; N350-I352 VanDerWaalsContact C-N 3.29Å; N350-I352 PolarHBondContact O-N 3.33Å; I352-R355 PolarHBondContact O-N 3.27Å; I352-R356 WeakPolarHBondContact O-CB 3.2Å; I352-R356 PolarHBondContact O-N 3.32Å
353A88.7Confident83Confident2 Ų246.7 Ų46.72%0.01724%0.244CC..Hα-helixtrans-67.4-41.8179.900000112.9W305 L320 C349 N350 R355 R356 H357W305-A353 HydrophobicContact CB-CB 3.88Å; L320-A353 HydrophobicContact CD2-CB 3.94Å; C349-A353 WeakPolarHBondContact O-CB 3.48Å; C349-A353 PolarHBondContact O-N 3.26Å; N350-A353 PolarHBondContact O-N 2.91Å; N350-A353 VanDerWaalsContact O-N 3.12Å; A353-R355 VanDerWaalsContact C-N 3.34Å; A353-R355 PolarHBondContact O-N 3.1Å; A353-R356 PolarHBondContact O-N 3.37Å; A353-H357 WeakPolarHBondContact O-CB 3.32Å; A353-H357 PolarHBondContact O-N 3.46Å
354I90.9Very high83.7Confident4 Ų446 Ų462%0.02125%0.248CC..Hα-helixtrans-57.7-49.1173.1-64.2159.4000109.5A301 N350 R356 H357 F358 I368 T371 Y383A301-I354 HydrophobicContact CB-CG2 4.34Å; A301-I354 VanDerWaalsContact O-CG1 3.3Å; A301-I354 WeakPolarHBondContact O-CG1 3.03Å; N350-I354 VanDerWaalsContact O-CG1 3.3Å; N350-I354 WeakPolarHBondContact O-CG1 3.21Å; N350-I354 PolarHBondContact O-N 3.43Å; I354-R356 PolarHBondContact O-N 2.8Å; I354-H357 WeakPolarHBondContact O-CB 3.46Å; I354-H357 PolarHBondContact O-N 3.07Å; I354-F358 HydrophobicContact CG2-CD2 4.26Å; I354-F358 HydrophobicContact CG2-CE2 3.73Å; I354-F358 WeakPolarHBondContact O-CD2 3.26Å; I354-F358 PolarHBondContact O-N 2.79Å; I354-I368 HydrophobicContact CB-CD1 4.11Å; I354-I368 HydrophobicContact CG2-CD1 3.6Å; I354-I368 HydrophobicContact CG2-CG1 4.25Å; I354-T371 HydrophobicContact CD1-CG2 3.93Å; I354-Y383 HydrophobicContact CD1-CD1 3.99Å; I354-Y383 HydrophobicContact CD1-CG 4.27Å; I354-Y383 HydrophobicContact CG2-CD1 4.44Å; I354-Y383 HydrophobicContact CG2-CD2 4.26Å; I354-Y383 HydrophobicContact CG2-CE1 4.23Å; I354-Y383 HydrophobicContact CG2-CE2 4.06Å; I354-Y383 HydrophobicContact CG2-CG 4.46Å
355R89Confident84.4Confident132 Ų13245.5 Ų45.550%0.49825%0.248SC..Hα-helixtrans-62.8-41.8177.4-171.7-178.9178.4-152-1.1112.4A351 I352 A353 F358 L359 I368A351-R355 WeakPolarHBondContact O-CB 3.21Å; A351-R355 PolarHBondContact O-N 3.37Å; A351-R355 VanDerWaalsContact O-N 3.1Å; I352-R355 PolarHBondContact O-N 3.27Å; A353-R355 VanDerWaalsContact C-N 3.34Å; A353-R355 PolarHBondContact O-N 3.1Å; R355-F358 PolarHBondContact O-N 3.02Å; R355-L359 HydrophobicContact CG-CD1 4.36Å; R355-L359 WeakPolarHBondContact O-CG 3.27Å; R355-L359 PolarHBondContact O-N 2.95Å; R355-I368 HydrophobicContact CB-CD1 3.87Å
356R88.1Confident85.5Confident46 Ų4643.3 Ų43.317%0.17424%0.237CC..Hα-helixtrans-67.6-37.3-178.6-172.569.9-168.996.97.3111.7Y308 L320 I352 A353 I354 L359 D360Y308-R356 HydrophobicContact CE1-CG 4.28Å; Y308-R356 HydrophobicContact CE2-CB 4.27Å; Y308-R356 HydrophobicContact CE2-CG 3.83Å; Y308-R356 VanDerWaalsContact OH-CG 3.24Å; Y308-R356 WeakPolarHBondContact OH-CG 3.37Å; L320-R356 HydrophobicContact CD2-CB 4.45Å; I352-R356 WeakPolarHBondContact O-CB 3.2Å; I352-R356 PolarHBondContact O-N 3.32Å; A353-R356 PolarHBondContact O-N 3.37Å; I354-R356 PolarHBondContact O-N 2.8Å; R356-L359 PolarHBondContact O-N 3.32Å; R356-D360 VanDerWaalsContact CZ-CG 3.42Å; R356-D360 IonicContact CZ-OD1 2.88Å; R356-D360 IonicContact CZ-OD2 3.93Å; R356-D360 VanDerWaalsContact CZ-OD2 3.27Å; R356-D360 IonicContact NE-OD2 2.78Å; R356-D360 IonicContact NH1-OD1 3.69Å; R356-D360 PolarHBondContact NH1-OD1 3.1Å; R356-D360 IonicContact NH1-OD2 2.63Å; R356-D360 PolarHBondContact NH1-OD2 3.49Å; R356-D360 IonicContact NH2-OD1 2.94Å; R356-D360 PolarHBondContact NH2-OD1 3.26Å; R356-D360 IonicContact NH2-OD2 2.68Å; R356-D360 PolarHBondContact NH2-OD2 3.09Å; R356-D360 PolarHBondContact O-N 3.42Å
357H90.8Very high86.6Confident9 Ų940.7 Ų40.74%0.04222%0.215CC..Hα-helixtrans-54.6-54.6173.2-173.2113.8000111.1L297 A301 Y308 A353 I354 L359 D360 E361L297-H357 PolarHBondContact O-NE2 3Å; A301-H357 HydrophobicContact CB-CB 4.29Å; Y308-H357 HydrophobicContact CD2-CB 4.47Å; A353-H357 WeakPolarHBondContact O-CB 3.32Å; A353-H357 PolarHBondContact O-N 3.46Å; I354-H357 WeakPolarHBondContact O-CB 3.46Å; I354-H357 PolarHBondContact O-N 3.07Å; H357-L359 VanDerWaalsContact C-N 3.29Å; H357-L359 PolarHBondContact O-N 2.82Å; H357-D360 PolarHBondContact O-N 3.41Å; H357-D360 VanDerWaalsContact O-N 3.12Å; H357-E361 WeakPolarHBondContact O-CG 3.21Å; H357-E361 PolarHBondContact O-N 2.68Å
358F92.1Very high87.8Confident5 Ų540.3 Ų40.32%0.02221%0.211CC..Hα-helixtrans-61.5-36.3178.4-66.5-57.1000113F298 A301 I354 R355 D360 E361 N362 M363 V366 Y383F298-F358 AromaticContact CD1-CE1 3.91Å; F298-F358 HydrophobicContact CD1-CE1 3.91Å; F298-F358 AromaticContact CD1-CZ 3.54Å; F298-F358 HydrophobicContact CD1-CZ 3.54Å; F298-F358 HydrophobicContact CD2-CE1 4.23Å; F298-F358 AromaticContact CE1-CE1 3.92Å; F298-F358 HydrophobicContact CE1-CE1 3.92Å; F298-F358 AromaticContact CE1-CZ 3.75Å; F298-F358 HydrophobicContact CE1-CZ 3.75Å; F298-F358 HydrophobicContact CE2-CE1 4.26Å; F298-F358 HydrophobicContact CG-CE1 4.07Å; F298-F358 HydrophobicContact CG-CZ 4.02Å; F298-F358 HydrophobicContact CZ-CE1 4.11Å; F298-F358 HydrophobicContact CZ-CZ 4.41Å; A301-F358 HydrophobicContact CB-CZ 4.3Å; I354-F358 HydrophobicContact CG2-CD2 4.26Å; I354-F358 HydrophobicContact CG2-CE2 3.73Å; I354-F358 WeakPolarHBondContact O-CD2 3.26Å; I354-F358 PolarHBondContact O-N 2.79Å; R355-F358 PolarHBondContact O-N 3.02Å; F358-D360 PolarHBondContact O-N 2.84Å; F358-E361 PolarHBondContact O-N 2.99Å; F358-N362 PolarHBondContact O-N 3.21Å; F358-M363 HydrophobicContact CB-CB 4.11Å; F358-M363 HydrophobicContact CD1-CB 4.15Å; F358-M363 HydrophobicContact CD1-CE 3.73Å; F358-M363 HydrophobicContact CD1-SD 3.98Å; F358-M363 HydrophobicContact CE1-CE 3.86Å; F358-M363 HydrophobicContact CE1-SD 4.46Å; F358-M363 WeakPolarHBondContact O-CA 3.46Å; F358-M363 WeakPolarHBondContact O-CB 3.49Å; F358-M363 PolarHBondContact O-N 3.25Å; F358-V366 HydrophobicContact CD1-CG1 4.38Å; F358-V366 HydrophobicContact CD2-CG1 4.09Å; F358-V366 HydrophobicContact CE1-CG1 4.34Å; F358-V366 HydrophobicContact CE2-CG1 4.04Å; F358-V366 HydrophobicContact CG-CB 4.39Å; F358-V366 HydrophobicContact CG-CG1 4.27Å; F358-V366 HydrophobicContact CZ-CG1 4.17Å; F358-Y383 HydrophobicContact CE2-CE2 4.23Å; F358-Y383 HydrophobicContact CZ-CE2 4.31Å; F358-Y383 WeakPolarHBondContact CZ-OH 3.38Å
359L89.1Confident88.7Confident73 Ų7339.7 Ų39.738%0.38221%0.205SC..Hα-helixtrans-65.9-33.4175.1-69.4171.7000113.3R355 R356 H357 N362 T364R355-L359 HydrophobicContact CG-CD1 4.36Å; R355-L359 WeakPolarHBondContact O-CG 3.27Å; R355-L359 PolarHBondContact O-N 2.95Å; R356-L359 PolarHBondContact O-N 3.32Å; H357-L359 VanDerWaalsContact C-N 3.29Å; H357-L359 PolarHBondContact O-N 2.82Å; L359-N362 PolarHBondContact O-N 3.22Å; L359-T364 HydrophobicContact CD2-CG2 4.22Å
360D88.4Confident89.3Confident51 Ų5138.5 Ų38.527%0.27320%0.197SC..Hα-helixtrans-76-25.3177.1-78.9-37.4000113.7Y308 R356 H357 F358 N362Y308-D360 WeakPolarHBondContact CE2-OD2 3.39Å; Y308-D360 PolarHBondContact OH-OD2 2.78Å; R356-D360 VanDerWaalsContact CZ-CG 3.42Å; R356-D360 IonicContact CZ-OD1 2.88Å; R356-D360 IonicContact CZ-OD2 3.93Å; R356-D360 VanDerWaalsContact CZ-OD2 3.27Å; R356-D360 IonicContact NE-OD2 2.78Å; R356-D360 IonicContact NH1-OD1 3.69Å; R356-D360 PolarHBondContact NH1-OD1 3.1Å; R356-D360 IonicContact NH1-OD2 2.63Å; R356-D360 PolarHBondContact NH1-OD2 3.49Å; R356-D360 IonicContact NH2-OD1 2.94Å; R356-D360 PolarHBondContact NH2-OD1 3.26Å; R356-D360 IonicContact NH2-OD2 2.68Å; R356-D360 PolarHBondContact NH2-OD2 3.09Å; R356-D360 PolarHBondContact O-N 3.42Å; H357-D360 PolarHBondContact O-N 3.41Å; H357-D360 VanDerWaalsContact O-N 3.12Å; F358-D360 PolarHBondContact O-N 2.84Å; D360-N362 VanDerWaalsContact C-N 3.27Å
361E89Confident89.7Confident62 Ų6237.1 Ų37.129%0.2919%0.189SC..THydrogen-bonded Turntrans-899.8173.8-56.2-63.9152.200112.6L297 R311 H357 F358 M363L297-E361 HydrophobicContact CD1-CB 4.38Å; L297-E361 HydrophobicContact CD1-CG 4.28Å; L297-E361 HydrophobicContact CD2-CG 3.92Å; R311-E361 IonicContact CZ-OE1 2.7Å; R311-E361 IonicContact NH1-OE1 3.47Å; R311-E361 PolarHBondContact NH1-OE1 2.91Å; R311-E361 IonicContact NH2-OE1 2.78Å; R311-E361 PolarHBondContact NH2-OE1 3.03Å; H357-E361 WeakPolarHBondContact O-CG 3.21Å; H357-E361 PolarHBondContact O-N 2.68Å; F358-E361 PolarHBondContact O-N 2.99Å; E361-M363 HydrophobicContact CB-CG 4.05Å; E361-M363 HydrophobicContact CB-SD 4.04Å; E361-M363 PolarHBondContact O-N 3.17Å
362N90.1Very high90Very high138 Ų13837.2 Ų37.274%0.73819%0.19SC*.THydrogen-bonded Turntrans57.720.3-173.5-59.8-67.8000115.1F358 L359 D360 T364F358-N362 PolarHBondContact O-N 3.21Å; L359-N362 PolarHBondContact O-N 3.22Å; D360-N362 VanDerWaalsContact C-N 3.27Å; N362-T364 PolarHBondContact O-N 3.44Å
363M91.2Very high90Very high15 Ų1537.9 Ų37.97%0.07420%0.195CC..  trans-82.556.6179.7-65176.358.700111.6Y294 L297 F298 F358 E361 A365 V366Y294-M363 HydrophobicContact CE1-CE 4.25Å; Y294-M363 HydrophobicContact CE2-CE 3.71Å; Y294-M363 HydrophobicContact CE2-SD 4.08Å; Y294-M363 WeakPolarHBondContact OH-CE 3.42Å; L297-M363 HydrophobicContact CB-SD 4.46Å; L297-M363 HydrophobicContact CD1-SD 3.54Å; L297-M363 VanDerWaalsContact CD1-SD 3.54Å; F298-M363 HydrophobicContact CD2-CE 4.36Å; F298-M363 HydrophobicContact CE2-CE 3.53Å; F298-M363 HydrophobicContact CZ-CE 3.83Å; F358-M363 HydrophobicContact CB-CB 4.11Å; F358-M363 HydrophobicContact CD1-CB 4.15Å; F358-M363 HydrophobicContact CD1-CE 3.73Å; F358-M363 HydrophobicContact CD1-SD 3.98Å; F358-M363 HydrophobicContact CE1-CE 3.86Å; F358-M363 HydrophobicContact CE1-SD 4.46Å; F358-M363 WeakPolarHBondContact O-CA 3.46Å; F358-M363 WeakPolarHBondContact O-CB 3.49Å; F358-M363 PolarHBondContact O-N 3.25Å; E361-M363 HydrophobicContact CB-CG 4.05Å; E361-M363 HydrophobicContact CB-SD 4.04Å; E361-M363 PolarHBondContact O-N 3.17Å; M363-A365 PolarHBondContact O-N 3.29Å; M363-V366 HydrophobicContact CB-CG2 4.14Å; M363-V366 HydrophobicContact CE-CG2 3.88Å; M363-V366 PolarHBondContact O-N 3.1Å
364T87.1Confident89.8Confident113 Ų11339.8 Ų39.869%0.69320%0.204SC*.THydrogen-bonded Turntrans-70.9-8.7-175.160.70000114.6L359 N362L359-T364 HydrophobicContact CD2-CG2 4.22Å; N362-T364 PolarHBondContact O-N 3.44Å
365A89.9Confident89.2Confident17 Ų1741.2 Ų41.214%0.1421%0.212CC..THydrogen-bonded Turntrans-9411.917800000113.8M363 H388 D389M363-A365 PolarHBondContact O-N 3.29Å; A365-H388 HydrophobicContact CB-CB 4.41Å; A365-H388 PolarHBondContact O-CD2 3.41Å; A365-H388 PolarHBondContact O-N 2.86Å; A365-H388 VanDerWaalsContact O-N 3.14Å; A365-D389 VanDerWaalsContact CB-CG 3.5Å; A365-D389 WeakPolarHBondContact CB-OD1 3.09Å; A365-D389 WeakPolarHBondContact CB-OD2 3Å
366V92.9Very high88.7Confident16 Ų1635.8 Ų35.810%0.09720%0.195CC..EExtended strand (participates in β ladder)trans-104.3110.4178-179.70000110.4F298 F358 M363 A385 V386 D387F298-V366 HydrophobicContact CE1-CG1 3.89Å; F298-V366 HydrophobicContact CZ-CG1 4.21Å; F298-V366 HydrophobicContact CZ-CG2 4.1Å; F358-V366 HydrophobicContact CD1-CG1 4.38Å; F358-V366 HydrophobicContact CD2-CG1 4.09Å; F358-V366 HydrophobicContact CE1-CG1 4.34Å; F358-V366 HydrophobicContact CE2-CG1 4.04Å; F358-V366 HydrophobicContact CG-CB 4.39Å; F358-V366 HydrophobicContact CG-CG1 4.27Å; F358-V366 HydrophobicContact CZ-CG1 4.17Å; M363-V366 HydrophobicContact CB-CG2 4.14Å; M363-V366 HydrophobicContact CE-CG2 3.88Å; M363-V366 PolarHBondContact O-N 3.1Å; V366-A385 HydrophobicContact CG1-CB 3.92Å; V366-V386 WeakPolarHBondContact CA-O 3.3Å; V366-D387 HydrophobicContact CG2-CB 4.44Å
367D90.4Very high88.1Confident66 Ų6635.9 Ų35.935%0.35320%0.201SC..EExtended strand (participates in β ladder)trans-98.8119.1177.4-91.4-36.2000111A385 V386 H388D367-A385 CarbonylContact O-C 3.57Å; D367-A385 VanDerWaalsContact O-CA 3.28Å; D367-A385 WeakPolarHBondContact O-CA 3.36Å; D367-V386 PolarHBondContact N-O 3.33Å; D367-V386 PolarHBondContact O-N 2.93Å; D367-H388 IonicContact OD2-NE2 3.82Å
368I91.8Very high87.8Confident14 Ų1439.1 Ų39.17%0.07221%0.213CC..EExtended strand (participates in β ladder)trans-73.1131171.7-53.9167.6000108.3V339 I354 R355 T371V339-I368 HydrophobicContact CG1-CG2 4.36Å; V339-I368 VanDerWaalsContact CG2-O 3.26Å; V339-I368 WeakPolarHBondContact CG2-O 3.43Å; I354-I368 HydrophobicContact CB-CD1 4.11Å; I354-I368 HydrophobicContact CG2-CD1 3.6Å; I354-I368 HydrophobicContact CG2-CG1 4.25Å; R355-I368 HydrophobicContact CB-CD1 3.87Å; I368-T371 WeakPolarHBondContact CG2-OG1 3.08Å
369V90.7Very high87.5Confident1 Ų141.9 Ų41.91%0.00623%0.226CC..EExtended strand (participates in β ladder)trans-107.8-40.7178.5177.40000111.1V339 T340 V384 V386 Q451 A452 R455V339-V369 WeakPolarHBondContact CA-O 3.16Å; T340-V369 PolarHBondContact N-O 3.48Å; V369-V384 PolarHBondContact N-O 3.35Å; V369-V386 HydrophobicContact CG2-CG2 3.72Å; V369-Q451 HydrophobicContact CG1-CB 4.06Å; V369-A452 HydrophobicContact CG1-CB 4.43Å; V369-A452 HydrophobicContact CG2-CB 4.38Å; V369-R455 HydrophobicContact CG2-CG 4.15Å
370Y92.8Very high87.5Confident1 Ų138.5 Ų38.50%0.00421%0.208CC..EExtended strand (participates in β ladder)trans-137.9146-176-171.2-96.9000111.1T340 E342 F382 Y383 V384 E446 V448T340-Y370 HydrophobicContact CG2-CD2 3.9Å; T340-Y370 HydrophobicContact CG2-CE2 3.78Å; T340-Y370 CarbonylContact O-C 3.45Å; T340-Y370 WeakPolarHBondContact O-CA 3.45Å; E342-Y370 PolarHBondContact OE2-OH 3.48Å; Y370-F382 HydrophobicContact CD1-CD2 4.48Å; Y370-F382 AromaticContact CD1-CE2 3.8Å; Y370-F382 HydrophobicContact CD1-CE2 3.8Å; Y370-F382 HydrophobicContact CD1-CZ 4.1Å; Y370-F382 HydrophobicContact CE1-CE1 4.28Å; Y370-F382 AromaticContact CE1-CE2 3.77Å; Y370-F382 HydrophobicContact CE1-CE2 3.77Å; Y370-F382 AromaticContact CE1-CZ 3.57Å; Y370-F382 HydrophobicContact CE1-CZ 3.57Å; Y370-Y383 CarbonylContact O-C 3.5Å; Y370-Y383 VanDerWaalsContact O-CA 3.29Å; Y370-Y383 WeakPolarHBondContact O-CA 3.25Å; Y370-Y383 VanDerWaalsContact O-CB 3.26Å; Y370-Y383 WeakPolarHBondContact O-CB 3.34Å; Y370-V384 PolarHBondContact N-O 3.47Å; Y370-V384 VanDerWaalsContact N-O 3.14Å; Y370-V384 PolarHBondContact O-N 3.06Å; Y370-E446 WeakPolarHBondContact CE2-OE2 3.27Å; Y370-E446 PolarHBondContact OH-OE2 2.88Å; Y370-V448 HydrophobicContact CD1-CG1 4.31Å; Y370-V448 HydrophobicContact CD2-CG1 4.11Å; Y370-V448 HydrophobicContact CD2-CG2 3.81Å; Y370-V448 HydrophobicContact CE2-CG2 3.95Å; Y370-V448 HydrophobicContact CG-CG1 3.73Å; Y370-V448 HydrophobicContact CG-CG2 4.11Å
371T92.2Very high87.7Confident3 Ų336.4 Ų36.42%0.01820%0.197CC..EExtended strand (participates in β ladder)trans-150.1116.4170.4-60.70000108.8T340 I341 E342 I354 I368T340-T371 PolarHBondContact O-N 3.24Å; I341-T371 CarbonylContact C-O 3.6Å; I341-T371 WeakPolarHBondContact CA-O 3.25Å; E342-T371 PolarHBondContact N-O 2.85Å; I354-T371 HydrophobicContact CD1-CG2 3.93Å; I368-T371 WeakPolarHBondContact CG2-OG1 3.08Å
372S90.9Very high88Confident3 Ų333.7 Ų33.72%0.02119%0.185CC..EExtended strand (participates in β ladder)trans-105.4123.2167-174.70000109.7E342 H374 F382E342-S372 VanDerWaalsContact OE2-CB 3.31Å; E342-S372 WeakPolarHBondContact OE2-CB 3.27Å; E342-S372 PolarHBondContact OE2-OG 3.3Å; S372-H374 PolarHBondContact OG-N 3.16Å; S372-F382 PolarHBondContact N-O 3.29Å; S372-F382 PolarHBondContact O-N 3.32Å
373C84.8Confident88.4Confident25 Ų2527.2 Ų27.217%0.16915%0.15CC..  trans-97.57.6173.6-60.40000112.2E342 D344 D375E342-C373 PolarHBondContact O-N 2.03Å; D344-C373 HydrophobicContact CB-CB 4.4Å; C373-D375 PolarHBondContact O-N 3.35Å
374H83.8Confident88.6Confident41 Ų4126.5 Ų26.519%0.1915%0.146CC..  trans-62.1132.4177.1-170.680.7000110.9E343 S372 A376 E379 P381E343-H374 VanDerWaalsContact CD-ND1 3.33Å; E343-H374 IonicContact OE1-ND1 2.7Å; E343-H374 IonicContact OE2-CE1 2.73Å; E343-H374 IonicContact OE2-CG 2.75Å; E343-H374 IonicContact OE2-ND1 2.72Å; E343-H374 PolarHBondContact OE2-ND1 2.99Å; S372-H374 PolarHBondContact OG-N 3.16Å; H374-A376 WeakPolarHBondContact NE2-CB 3.46Å; H374-E379 IonicContact CD2-OE2 3.44Å; H374-E379 PolarHBondContact CD2-OE2 2.98Å; H374-E379 VanDerWaalsContact CD2-OE2 3.27Å; H374-E379 IonicContact NE2-OE2 2.71Å; H374-E379 PolarHBondContact NE2-OE2 2.99Å; H374-P381 WeakPolarHBondContact O-CD 3.43Å; H374-P381 WeakPolarHBondContact O-CG 3.4Å
375D79.3Confident89Confident35 Ų3521.1 Ų21.119%0.18711%0.113CC..  trans-133.298.4-169.8-175-51.3000107.6C373 P381 R398 S402 K404C373-D375 PolarHBondContact O-N 3.35Å; D375-P381 HydrophobicContact CB-CG 4.25Å; D375-R398 IonicContact OD2-CZ 3.76Å; D375-R398 IonicContact OD2-NH1 2.67Å; D375-R398 PolarHBondContact OD2-NH1 3.37Å; D375-R398 IonicContact OD2-NH2 3.37Å; D375-R398 PolarHBondContact OD2-NH2 3.03Å; D375-S402 WeakPolarHBondContact OD1-CB 3.43Å; D375-S402 PolarHBondContact OD1-OG 3.35Å; D375-S402 VanDerWaalsContact OD2-CB 3.26Å; D375-S402 WeakPolarHBondContact OD2-CB 3.5Å; D375-S402 PolarHBondContact OD2-OG 3.46Å; D375-K404 WeakPolarHBondContact O-CD 3.37Å; D375-K404 WeakPolarHBondContact O-CE 3.49Å; D375-K404 PolarHBondContact O-NZ 3.35Å
376A77.7Confident89.3Confident18 Ų1820.3 Ų20.315%0.14911%0.107CC..BIsolated β-bridgetrans-136.9171.6173.100000111.6H374 Y378 E379H374-A376 WeakPolarHBondContact NE2-CB 3.46Å; A376-Y378 PolarHBondContact O-N 3.29Å; A376-E379 HydrophobicContact CB-CB 3.91Å; A376-E379 HydrophobicContact CB-CG 4.14Å; A376-E379 PolarHBondContact N-O 2.94Å; A376-E379 VanDerWaalsContact N-O 3.14Å; A376-E379 CarbonylContact O-C 3.58Å; A376-E379 PolarHBondContact O-N 3.49Å
377V75.7Confident89.4Confident48 Ų4819.6 Ų19.629%0.29110%0.102SC..THydrogen-bonded Turntrans-67.2125.3178.9-1700000107.7E379 K404 L407V377-E379 PolarHBondContact O-N 3.43Å; V377-K404 HydrophobicContact CG2-CB 4.09Å; V377-K404 HydrophobicContact CG2-CG 4.49Å; V377-L407 HydrophobicContact CG1-CD2 4.18Å; V377-L407 HydrophobicContact CG1-CG 4.28Å; V377-L407 HydrophobicContact CG2-CD2 4.05Å
378Y83.9Confident89.6Confident76 Ų7617.1 Ų17.130%0.2989%0.089SC..THydrogen-bonded Turntrans64.610.2-168.3-35.7-62.4000116.2A376 T408 T411 L434 S435A376-Y378 PolarHBondContact O-N 3.29Å; Y378-T408 HydrophobicContact CD1-CG2 4Å; Y378-T408 PolarHBondContact N-OG1 3.43Å; Y378-T408 VanDerWaalsContact N-OG1 3.12Å; Y378-T411 HydrophobicContact CE1-CG2 4Å; Y378-L434 HydrophobicContact CD1-CB 4.11Å; Y378-L434 HydrophobicContact CD1-CD1 3.81Å; Y378-L434 HydrophobicContact CD2-CD1 4.06Å; Y378-L434 HydrophobicContact CE1-CD1 3.92Å; Y378-L434 HydrophobicContact CE2-CD1 4.15Å; Y378-L434 HydrophobicContact CG-CB 3.99Å; Y378-L434 HydrophobicContact CG-CD1 3.89Å; Y378-S435 WeakPolarHBondContact O-CA 3.37Å
379E86.8Confident89.7Confident64 Ų6422 Ų2230%0.29912%0.115SC..BIsolated β-bridgetrans-122.583.7176.1-55.9-169-14800109.3H374 A376 V377 Y438H374-E379 IonicContact CD2-OE2 3.44Å; H374-E379 PolarHBondContact CD2-OE2 2.98Å; H374-E379 VanDerWaalsContact CD2-OE2 3.27Å; H374-E379 IonicContact NE2-OE2 2.71Å; H374-E379 PolarHBondContact NE2-OE2 2.99Å; A376-E379 HydrophobicContact CB-CB 3.91Å; A376-E379 HydrophobicContact CB-CG 4.14Å; A376-E379 PolarHBondContact N-O 2.94Å; A376-E379 VanDerWaalsContact N-O 3.14Å; A376-E379 CarbonylContact O-C 3.58Å; A376-E379 PolarHBondContact O-N 3.49Å; V377-E379 PolarHBondContact O-N 3.43Å; E379-Y438 HydrophobicContact CB-CD1 4.1Å; E379-Y438 HydrophobicContact CB-CD2 4.36Å; E379-Y438 HydrophobicContact CB-CE1 3.77Å; E379-Y438 HydrophobicContact CB-CE2 4.03Å; E379-Y438 HydrophobicContact CB-CG 4.36Å; E379-Y438 HydrophobicContact CG-CD1 4.32Å; E379-Y438 HydrophobicContact CG-CD2 3.73Å; E379-Y438 HydrophobicContact CG-CE1 4.2Å; E379-Y438 HydrophobicContact CG-CE2 3.56Å; E379-Y438 HydrophobicContact CG-CG 4.08Å; E379-Y438 WeakPolarHBondContact OE2-CE2 3.46Å; E379-Y438 PolarHBondContact OE2-OH 3.38Å
380T88.3Confident89.8Confident1 Ų126.7 Ų26.71%0.00614%0.135CC..  trans-82131.8-176.1-43.20000112.1I397 R398 S435 L473T380-I397 HydrophobicContact CG2-CG2 3.91Å; T380-R398 VanDerWaalsContact CG2-O 3.23Å; T380-R398 WeakPolarHBondContact CG2-O 3.31Å; T380-S435 PolarHBondContact OG1-OG 3.03Å; T380-L473 HydrophobicContact CG2-CD2 4.21Å; T380-L473 HydrophobicContact CG2-CG 4.46Å
381P92.8Very high90Very high8 Ų832.8 Ų32.85%0.05216%0.162CC..  trans-56.2142.3173-26.232.2000113.9H374 D375 R398H374-P381 WeakPolarHBondContact O-CD 3.43Å; H374-P381 WeakPolarHBondContact O-CG 3.4Å; D375-P381 HydrophobicContact CB-CG 4.25Å; P381-R398 HydrophobicContact CB-CB 4.11Å; P381-R398 WeakPolarHBondContact O-CB 3.36Å; P381-R398 PolarHBondContact O-N 2.86Å
382F96.3Very high90.2Very high5 Ų535.4 Ų35.42%0.02217%0.173CC..EExtended strand (participates in β ladder)trans-153.4160.9177.974.1-81.9000112.2Y370 S372 V384 I395 S396 I397 I439 K442 L443Y370-F382 HydrophobicContact CD1-CD2 4.48Å; Y370-F382 AromaticContact CD1-CE2 3.8Å; Y370-F382 HydrophobicContact CD1-CE2 3.8Å; Y370-F382 HydrophobicContact CD1-CZ 4.1Å; Y370-F382 HydrophobicContact CE1-CE1 4.28Å; Y370-F382 AromaticContact CE1-CE2 3.77Å; Y370-F382 HydrophobicContact CE1-CE2 3.77Å; Y370-F382 AromaticContact CE1-CZ 3.57Å; Y370-F382 HydrophobicContact CE1-CZ 3.57Å; S372-F382 PolarHBondContact N-O 3.29Å; S372-F382 PolarHBondContact O-N 3.32Å; F382-V384 HydrophobicContact CD2-CG2 4.28Å; F382-V384 HydrophobicContact CE2-CG2 4.15Å; F382-I395 HydrophobicContact CD2-CG2 4.39Å; F382-S396 CarbonylContact C-O 3.56Å; F382-S396 VanDerWaalsContact CA-O 3.31Å; F382-S396 WeakPolarHBondContact CA-O 3.44Å; F382-S396 WeakPolarHBondContact CB-O 3.21Å; F382-I397 HydrophobicContact CB-CB 4.47Å; F382-I397 HydrophobicContact CB-CG1 4.26Å; F382-I397 HydrophobicContact CB-CG2 4.49Å; F382-I439 HydrophobicContact CB-CD1 4.32Å; F382-I439 HydrophobicContact CD1-CB 4.49Å; F382-I439 HydrophobicContact CD1-CD1 4.08Å; F382-I439 HydrophobicContact CD1-CG1 3.74Å; F382-I439 HydrophobicContact CD1-CG2 4.14Å; F382-I439 HydrophobicContact CD2-CG2 4.15Å; F382-I439 HydrophobicContact CE1-CB 4.42Å; F382-I439 HydrophobicContact CE1-CG1 3.99Å; F382-I439 HydrophobicContact CE1-CG2 4.1Å; F382-I439 HydrophobicContact CE2-CG2 4.12Å; F382-I439 HydrophobicContact CG-CD1 4.32Å; F382-I439 HydrophobicContact CG-CG1 4.34Å; F382-I439 HydrophobicContact CG-CG2 4.16Å; F382-I439 HydrophobicContact CZ-CG2 4.09Å; F382-K442 HydrophobicContact CE1-CB 4.29Å; F382-K442 HydrophobicContact CZ-CB 4.06Å; F382-L443 HydrophobicContact CE2-CD2 3.8Å; F382-L443 HydrophobicContact CE2-CG 4.26Å; F382-L443 HydrophobicContact CZ-CD2 4.41Å
383Y96.4Very high90.5Very high2 Ų235.2 Ų35.21%0.00817%0.172CC..EExtended strand (participates in β ladder)trans-133.815917276.8-92.7000111.4F298 A301 A302 I354 F358 Y370 A385 S396F298-Y383 WeakPolarHBondContact CA-OH 3.49Å; F298-Y383 WeakPolarHBondContact CB-OH 3.49Å; F298-Y383 HydrophobicContact CD1-CE2 4.45Å; F298-Y383 PolarHBondContact O-OH 3.48Å; A301-Y383 HydrophobicContact CB-CE1 4.48Å; A302-Y383 HydrophobicContact CB-CD1 4.17Å; A302-Y383 HydrophobicContact CB-CE1 3.8Å; I354-Y383 HydrophobicContact CD1-CD1 3.99Å; I354-Y383 HydrophobicContact CD1-CG 4.27Å; I354-Y383 HydrophobicContact CG2-CD1 4.44Å; I354-Y383 HydrophobicContact CG2-CD2 4.26Å; I354-Y383 HydrophobicContact CG2-CE1 4.23Å; I354-Y383 HydrophobicContact CG2-CE2 4.06Å; I354-Y383 HydrophobicContact CG2-CG 4.46Å; F358-Y383 HydrophobicContact CE2-CE2 4.23Å; F358-Y383 HydrophobicContact CZ-CE2 4.31Å; F358-Y383 WeakPolarHBondContact CZ-OH 3.38Å; Y370-Y383 CarbonylContact O-C 3.5Å; Y370-Y383 VanDerWaalsContact O-CA 3.29Å; Y370-Y383 WeakPolarHBondContact O-CA 3.25Å; Y370-Y383 VanDerWaalsContact O-CB 3.26Å; Y370-Y383 WeakPolarHBondContact O-CB 3.34Å; Y383-A385 HydrophobicContact CD2-CB 4.26Å; Y383-A385 HydrophobicContact CE2-CB 4.02Å; Y383-S396 WeakPolarHBondContact CE1-OG 3.41Å; Y383-S396 VanDerWaalsContact CZ-CB 3.4Å; Y383-S396 PolarHBondContact N-O 3.3Å; Y383-S396 PolarHBondContact O-N 2.96Å
384V96.9Very high91.1Very high0 Ų034 Ų340%016%0.164CC..EExtended strand (participates in β ladder)trans-124.9128.2175.4-173.60000109.4V369 Y370 F382 V393 V394 I395 L443 V448 A452V369-V384 PolarHBondContact N-O 3.35Å; Y370-V384 PolarHBondContact N-O 3.47Å; Y370-V384 VanDerWaalsContact N-O 3.14Å; Y370-V384 PolarHBondContact O-N 3.06Å; F382-V384 HydrophobicContact CD2-CG2 4.28Å; F382-V384 HydrophobicContact CE2-CG2 4.15Å; V384-V393 HydrophobicContact CG1-CG1 3.73Å; V384-V394 WeakPolarHBondContact CA-O 3.21Å; V384-I395 HydrophobicContact CG2-CG1 4.26Å; V384-L443 HydrophobicContact CG2-CD2 3.81Å; V384-V448 HydrophobicContact CB-CG1 4.05Å; V384-V448 HydrophobicContact CG1-CG1 4.45Å; V384-V448 HydrophobicContact CG2-CG1 3.76Å; V384-A452 HydrophobicContact CG1-CB 4.18Å
385A95.8Very high91.8Very high0 Ų032.1 Ų32.10%016%0.155CC..EExtended strand (participates in β ladder)trans-128.315717900000112F298 V366 D367 Y383 V394F298-A385 HydrophobicContact CE1-CB 4.4Å; V366-A385 HydrophobicContact CG1-CB 3.92Å; D367-A385 CarbonylContact O-C 3.57Å; D367-A385 VanDerWaalsContact O-CA 3.28Å; D367-A385 WeakPolarHBondContact O-CA 3.36Å; Y383-A385 HydrophobicContact CD2-CB 4.26Å; Y383-A385 HydrophobicContact CE2-CB 4.02Å; A385-V394 PolarHBondContact N-O 3.34Å; A385-V394 PolarHBondContact O-N 3.49Å
386V95.6Very high92.7Very high0 Ų030.4 Ų30.40%015%0.146CC..EExtended strand (participates in β ladder)trans-110.9118.9175.1-179.80000108.3V366 D367 V369 V393 A452 R455 T461 Y464V366-V386 WeakPolarHBondContact CA-O 3.3Å; D367-V386 PolarHBondContact N-O 3.33Å; D367-V386 PolarHBondContact O-N 2.93Å; V369-V386 HydrophobicContact CG2-CG2 3.72Å; V386-V393 HydrophobicContact CG2-CG2 4.4Å; V386-A452 HydrophobicContact CG2-CB 4Å; V386-R455 HydrophobicContact CG2-CB 4.24Å; V386-T461 HydrophobicContact CG1-CG2 4.03Å; V386-Y464 HydrophobicContact CG1-CD2 3.94Å; V386-Y464 HydrophobicContact CG1-CE2 3.75Å
387D95.5Very high93.7Very high0 Ų029.6 Ų29.60%014%0.139CC..EExtended strand (participates in β ladder)trans-99.4107175.8174.1-12.3000108.6Y294 F298 V366 D389 K390 K391 K392 V394Y294-D387 WeakPolarHBondContact CE1-OD2 3.25Å; Y294-D387 PolarHBondContact OH-OD2 3.07Å; F298-D387 HydrophobicContact CZ-CB 4.36Å; V366-D387 HydrophobicContact CG2-CB 4.44Å; D387-D389 PolarHBondContact OD1-N 3.19Å; D387-K390 PolarHBondContact OD1-N 2.92Å; D387-K390 VanDerWaalsContact OD2-CB 3.26Å; D387-K390 WeakPolarHBondContact OD2-CB 3.33Å; D387-K390 WeakPolarHBondContact OD2-CG 3.42Å; D387-K391 CarbonylContact O-C 3.6Å; D387-K391 VanDerWaalsContact O-CA 3.24Å; D387-K391 WeakPolarHBondContact O-CA 3.45Å; D387-K391 PolarHBondContact O-N 3.38Å; D387-K392 HydrophobicContact CB-CB 4.43Å; D387-K392 PolarHBondContact N-O 2.93Å; D387-K392 PolarHBondContact O-N 3.43Å; D387-V394 HydrophobicContact CB-CG2 4.47Å
388H94.4Very high94.6Very high15 Ų1528.5 Ų28.57%0.06913%0.129CC..THydrogen-bonded Turntrans-77.6-23.4-178.6-68.9-71.9000113.7A365 D367 R459 Y464A365-H388 HydrophobicContact CB-CB 4.41Å; A365-H388 PolarHBondContact O-CD2 3.41Å; A365-H388 PolarHBondContact O-N 2.86Å; A365-H388 VanDerWaalsContact O-N 3.14Å; D367-H388 IonicContact OD2-NE2 3.82Å; H388-R459 PolarHBondContact CD2-NH1 3Å; H388-R459 VanDerWaalsContact CG-NH1 3.33Å; H388-R459 WeakPolarHBondContact ND1-CD 3.37Å; H388-Y464 AromaticContact ND1-CE2 3.61Å; H388-Y464 AromaticContact ND1-CZ 3.68Å; H388-Y464 PolarHBondContact ND1-OH 2.8Å
389D93.1Very high94.9Very high116 Ų11624.9 Ų24.962%0.6212%0.115SC*.THydrogen-bonded Turntrans-78.8-42.1-178.3-71.5-18.3000111.3A365 D387A365-D389 VanDerWaalsContact CB-CG 3.5Å; A365-D389 WeakPolarHBondContact CB-OD1 3.09Å; A365-D389 WeakPolarHBondContact CB-OD2 3Å; D387-D389 PolarHBondContact OD1-N 3.19Å
390K93.9Very high94.7Very high99 Ų9923.9 Ų23.943%0.4311%0.114SC..THydrogen-bonded Turntrans-86.8-9.8173.1-53.4-59.8-178.5-177.40113.3Y294 D387 K392Y294-K390 HydrophobicContact CD1-CG 4.37Å; Y294-K390 HydrophobicContact CE1-CD 4.23Å; Y294-K390 VanDerWaalsContact CE1-CE 3.5Å; Y294-K390 HydrophobicContact CE1-CG 3.61Å; D387-K390 PolarHBondContact OD1-N 2.92Å; D387-K390 VanDerWaalsContact OD2-CB 3.26Å; D387-K390 WeakPolarHBondContact OD2-CB 3.33Å; D387-K390 WeakPolarHBondContact OD2-CG 3.42Å; K390-K392 HydrophobicContact CB-CG 3.87Å; K390-K392 WeakPolarHBondContact O-CE 3.41Å
391K95.3Very high94.2Very high130 Ų13027 Ų2757%0.56513%0.13SC*.THydrogen-bonded Turntrans55.158.3-173-58.2-175.3-176.5-176.90111.3D387 Y464 G465D387-K391 CarbonylContact O-C 3.6Å; D387-K391 VanDerWaalsContact O-CA 3.24Å; D387-K391 WeakPolarHBondContact O-CA 3.45Å; D387-K391 PolarHBondContact O-N 3.38Å; K391-Y464 VanDerWaalsContact C-CD2 3.42Å; K391-Y464 HydrophobicContact CB-CD1 3.67Å; K391-Y464 HydrophobicContact CB-CD2 4.34Å; K391-Y464 HydrophobicContact CB-CE1 3.74Å; K391-Y464 HydrophobicContact CB-CE2 4.38Å; K391-Y464 HydrophobicContact CB-CG 4.01Å; K391-Y464 HydrophobicContact CD-CE1 4.26Å; K391-Y464 HydrophobicContact CG-CD1 4.31Å; K391-Y464 HydrophobicContact CG-CE1 3.86Å; K391-Y464 VanDerWaalsContact O-CA 3.31Å; K391-Y464 WeakPolarHBondContact O-CA 3.37Å; K391-Y464 VanDerWaalsContact O-CB 3.32Å; K391-Y464 WeakPolarHBondContact O-CB 3.13Å; K391-G465 PolarHBondContact O-N 3.25Å
392K96.7Very high92.8Very high57 Ų5727.4 Ų27.425%0.24813%0.133CC..EExtended strand (participates in β ladder)trans-129.9150.6-179.3-57.4-60.6164.1-163.60112.8D387 K390 V394 G465 I467D387-K392 HydrophobicContact CB-CB 4.43Å; D387-K392 PolarHBondContact N-O 2.93Å; D387-K392 PolarHBondContact O-N 3.43Å; K390-K392 HydrophobicContact CB-CG 3.87Å; K390-K392 WeakPolarHBondContact O-CE 3.41Å; K392-V394 HydrophobicContact CB-CG2 4.19Å; K392-G465 CarbonylContact C-O 3.5Å; K392-G465 WeakPolarHBondContact CA-O 3.46Å; K392-G465 WeakPolarHBondContact CD-O 3.47Å; K392-I467 HydrophobicContact CB-CG1 3.98Å; K392-I467 HydrophobicContact CD-CD1 4.11Å; K392-I467 HydrophobicContact CD-CG1 3.92Å; K392-I467 HydrophobicContact CG-CD1 4.44Å; K392-I467 HydrophobicContact CG-CG1 3.84Å
393V97.6Very high90.8Very high0 Ų028.4 Ų28.40%014%0.14CC..EExtended strand (participates in β ladder)trans-97.9132.2155.2177.80000106.5V384 V386 L449 A452 F453 G465 L466 I467V384-V393 HydrophobicContact CG1-CG1 3.73Å; V386-V393 HydrophobicContact CG2-CG2 4.4Å; V393-L449 HydrophobicContact CG1-CD2 4.37Å; V393-A452 HydrophobicContact CG1-CB 3.74Å; V393-A452 HydrophobicContact CG2-CB 4.1Å; V393-F453 HydrophobicContact CB-CE1 4Å; V393-F453 HydrophobicContact CB-CZ 4.16Å; V393-F453 HydrophobicContact CG2-CD1 3.55Å; V393-F453 HydrophobicContact CG2-CE1 3.39Å; V393-F453 HydrophobicContact CG2-CG 4.23Å; V393-F453 HydrophobicContact CG2-CZ 3.96Å; V393-G465 PolarHBondContact N-O 3.38Å; V393-L466 HydrophobicContact CB-CD1 4.02Å; V393-L466 HydrophobicContact CG1-CD1 3.97Å; V393-I467 PolarHBondContact O-N 2.95Å
394V98.1Very high89.5Confident0 Ų030.7 Ų30.70%015%0.15CC..EExtended strand (participates in β ladder)trans-120.1116.4-176.7-171.90000109Y295 F298 V384 A385 D387 K392 I467 V469Y295-V394 HydrophobicContact CE1-CG2 4.21Å; F298-V394 HydrophobicContact CB-CG1 4.29Å; F298-V394 HydrophobicContact CD1-CB 3.98Å; F298-V394 HydrophobicContact CD1-CG1 3.66Å; F298-V394 HydrophobicContact CD1-CG2 4.28Å; F298-V394 HydrophobicContact CE1-CB 3.97Å; F298-V394 HydrophobicContact CE1-CG1 4.13Å; F298-V394 HydrophobicContact CE1-CG2 3.87Å; F298-V394 HydrophobicContact CG-CG1 4.02Å; F298-V394 HydrophobicContact CZ-CG2 4.14Å; V384-V394 WeakPolarHBondContact CA-O 3.21Å; A385-V394 PolarHBondContact N-O 3.34Å; A385-V394 PolarHBondContact O-N 3.49Å; D387-V394 HydrophobicContact CB-CG2 4.47Å; K392-V394 HydrophobicContact CB-CG2 4.19Å; V394-I467 WeakPolarHBondContact CA-O 3.29Å; V394-I467 HydrophobicContact CG1-CB 4.4Å; V394-I467 HydrophobicContact CG1-CG2 4.32Å; V394-I467 HydrophobicContact CG2-CB 4.25Å; V394-V469 HydrophobicContact CG1-CG1 3.63Å
395I98.4Very high88.4Confident0 Ų030.7 Ų30.70%015%0.15CC..EExtended strand (participates in β ladder)trans-90.9119.6167.2-55.6162.5000106.9F382 V384 I397 L443 L449 L466 I467 V468 V469 L481 L485F382-I395 HydrophobicContact CD2-CG2 4.39Å; V384-I395 HydrophobicContact CG2-CG1 4.26Å; I395-I397 HydrophobicContact CG2-CG1 4.35Å; I395-L443 HydrophobicContact CD1-CD1 3.81Å; I395-L443 HydrophobicContact CG1-CD1 4.5Å; I395-L449 HydrophobicContact CD1-CD2 4.03Å; I395-L449 HydrophobicContact CG1-CD2 4.14Å; I395-L466 HydrophobicContact CD1-CD1 3.96Å; I395-L466 HydrophobicContact CD1-CD2 4.43Å; I395-L466 HydrophobicContact CD1-CG 4.49Å; I395-L466 HydrophobicContact CG1-CD1 4.12Å; I395-I467 PolarHBondContact N-O 3.27Å; I395-V468 HydrophobicContact CB-CG1 4.31Å; I395-V468 HydrophobicContact CD1-CG2 4.35Å; I395-V468 HydrophobicContact CG2-CG1 4.47Å; I395-V468 CarbonylContact O-C 2.92Å; I395-V468 WeakPolarHBondContact O-CA 3.48Å; I395-V469 WeakPolarHBondContact O-CG1 3.47Å; I395-V469 PolarHBondContact O-N 2.92Å; I395-L481 HydrophobicContact CD1-CD2 4.49Å; I395-L481 HydrophobicContact CG2-CD2 4.21Å; I395-L485 HydrophobicContact CD1-CD1 3.7Å
396S98.1Very high87Confident0 Ų031.8 Ų31.80%016%0.159CC..EExtended strand (participates in β ladder)trans-120.6121.5-178.5-172.30000111.3F298 F382 Y383 V469F298-S396 PolarHBondContact O-OG 3.23Å; F382-S396 CarbonylContact C-O 3.56Å; F382-S396 VanDerWaalsContact CA-O 3.31Å; F382-S396 WeakPolarHBondContact CA-O 3.44Å; F382-S396 WeakPolarHBondContact CB-O 3.21Å; Y383-S396 WeakPolarHBondContact CE1-OG 3.41Å; Y383-S396 VanDerWaalsContact CZ-CB 3.4Å; Y383-S396 PolarHBondContact N-O 3.3Å; Y383-S396 PolarHBondContact O-N 2.96Å; S396-V469 WeakPolarHBondContact CA-O 3.38Å
397I97.9Very high85.4Confident0 Ų033 Ų330%017%0.165CC..EExtended strand (participates in β ladder)trans-107.2133.7-172.1-48.6178.8000109.6T380 F382 I395 I439 V468 V469 T477 A478 L481T380-I397 HydrophobicContact CG2-CG2 3.91Å; F382-I397 HydrophobicContact CB-CB 4.47Å; F382-I397 HydrophobicContact CB-CG1 4.26Å; F382-I397 HydrophobicContact CB-CG2 4.49Å; I395-I397 HydrophobicContact CG2-CG1 4.35Å; I397-I439 HydrophobicContact CD1-CD1 3.82Å; I397-I439 HydrophobicContact CG1-CD1 4.12Å; I397-I439 HydrophobicContact CG2-CD1 3.78Å; I397-V468 HydrophobicContact CD1-CG1 4.3Å; I397-V469 PolarHBondContact N-O 2.85Å; I397-T477 HydrophobicContact CD1-CG2 3.99Å; I397-T477 HydrophobicContact CG2-CG2 4.36Å; I397-A478 HydrophobicContact CD1-CB 4.03Å; I397-L481 HydrophobicContact CD1-CD2 3.93Å
398R95.4Very high84.1Confident25 Ų2533 Ų339%0.09417%0.165CC..  trans-67.5146.3177.6-157.8-173.677.1-167.2-4.7110.2A302 Y303 D375 T380 P381 D405 G474A302-R398 HydrophobicContact CB-CB 4.37Å; A302-R398 WeakPolarHBondContact O-CG 3.34Å; Y303-R398 HydrophobicContact CD1-CG 3.89Å; Y303-R398 HydrophobicContact CE1-CG 4.24Å; Y303-R398 HydrophobicContact CG-CG 4.17Å; D375-R398 IonicContact OD2-CZ 3.76Å; D375-R398 IonicContact OD2-NH1 2.67Å; D375-R398 PolarHBondContact OD2-NH1 3.37Å; D375-R398 IonicContact OD2-NH2 3.37Å; D375-R398 PolarHBondContact OD2-NH2 3.03Å; T380-R398 VanDerWaalsContact CG2-O 3.23Å; T380-R398 WeakPolarHBondContact CG2-O 3.31Å; P381-R398 HydrophobicContact CB-CB 4.11Å; P381-R398 WeakPolarHBondContact O-CB 3.36Å; P381-R398 PolarHBondContact O-N 2.86Å; R398-D405 IonicContact CZ-OD2 3.15Å; R398-D405 IonicContact NE-OD2 2.78Å; R398-D405 IonicContact NH2-OD1 2.69Å; R398-D405 PolarHBondContact NH2-OD1 3Å; R398-D405 IonicContact NH2-OD2 2.79Å; R398-D405 PolarHBondContact NH2-OD2 2.95Å; R398-G474 VanDerWaalsContact O-CA 3.25Å; R398-G474 WeakPolarHBondContact O-CA 3.2Å; R398-G474 PolarHBondContact O-N 3.15Å
399G90.6Very high83.2Confident0 Ų034.3 Ų34.30%017%0.172CC..  trans-89.4-172.2162.800000112.4Y303 L401 H471Y303-G399 WeakPolarHBondContact OH-CA 3.38Å; G399-L401 PolarHBondContact O-N 2.92Å; G399-H471 WeakPolarHBondContact CA-O 3.39Å
400T82.4Confident82Confident44 Ų4432.2 Ų32.227%0.2716%0.161SC..SBendtrans-58.4119-176.9-35.90000112.2D405 A406 D409 L473T400-D405 WeakPolarHBondContact CA-OD2 3.46Å; T400-D405 HydrophobicContact CG2-CB 3.64Å; T400-A406 HydrophobicContact CG2-CB 4.29Å; T400-D409 WeakPolarHBondContact CB-OD2 3.47Å; T400-D409 WeakPolarHBondContact CG2-OD2 3.1Å; T400-D409 PolarHBondContact OG1-OD2 2.94Å; T400-L473 WeakPolarHBondContact OG1-CB 3.31Å
401L76.9Confident80.8Confident66 Ų6628.4 Ų28.435%0.34615%0.146SC..  trans-141.9-14175.5-163.367.4000112.1Y303 G399 D405Y303-L401 HydrophobicContact CD1-CB 4.23Å; Y303-L401 HydrophobicContact CD1-CD1 4.06Å; Y303-L401 HydrophobicContact CD1-CD2 4.23Å; Y303-L401 HydrophobicContact CD1-CG 4.41Å; Y303-L401 HydrophobicContact CE1-CB 4.37Å; G399-L401 PolarHBondContact O-N 2.92Å; L401-D405 PolarHBondContact N-OD2 3.04Å
402S63.3Low79.3Confident16 Ų1623 Ų2311%0.11213%0.128CC..SBendtrans-121.7159.9179.8102.40000113.2D375 K404 D405 A406D375-S402 WeakPolarHBondContact OD1-CB 3.43Å; D375-S402 PolarHBondContact OD1-OG 3.35Å; D375-S402 VanDerWaalsContact OD2-CB 3.26Å; D375-S402 WeakPolarHBondContact OD2-CB 3.5Å; D375-S402 PolarHBondContact OD2-OG 3.46Å; S402-K404 PolarHBondContact O-N 2.7Å; S402-K404 WeakPolarHBondContact OG-CB 3.39Å; S402-K404 PolarHBondContact OG-N 2.99Å; S402-D405 PolarHBondContact N-OD2 3.46Å; S402-D405 WeakPolarHBondContact O-CB 3.23Å; S402-D405 PolarHBondContact O-N 3.31Å; S402-D405 PolarHBondContact OG-N 3.41Å; S402-A406 PolarHBondContact O-N 3.22Å; S402-A406 VanDerWaalsContact O-N 3.12Å
403P54.3Low78.4Confident27 Ų2724.5 Ų24.518%0.17514%0.138CC..Hα-helixtrans-62.1-17.6171.4-23.134.3000114.3A214 Y215 L407A214-P403 HydrophobicContact CB-CB 4.45Å; Y215-P403 HydrophobicContact CE1-CB 4.45Å; Y215-P403 HydrophobicContact CE1-CG 4.32Å; P403-L407 PolarHBondContact O-N 2.88Å
404K68.8Low77.8Confident50 Ų5026.5 Ų26.522%0.21715%0.154CC..Hα-helixtrans-83.4-37.1177.7-50.1-173.4-168.2175.10111.6D375 V377 S402 A406 L407 T408D375-K404 WeakPolarHBondContact O-CD 3.37Å; D375-K404 WeakPolarHBondContact O-CE 3.49Å; D375-K404 PolarHBondContact O-NZ 3.35Å; V377-K404 HydrophobicContact CG2-CB 4.09Å; V377-K404 HydrophobicContact CG2-CG 4.49Å; S402-K404 PolarHBondContact O-N 2.7Å; S402-K404 WeakPolarHBondContact OG-CB 3.39Å; S402-K404 PolarHBondContact OG-N 2.99Å; K404-A406 VanDerWaalsContact C-N 3.31Å; K404-L407 PolarHBondContact O-N 3.17Å; K404-T408 PolarHBondContact O-N 2.99Å; K404-T408 PolarHBondContact O-OG1 3.12Å
405D73.4Confident77.3Confident0 Ų029.9 Ų29.90%017%0.17CC..Hα-helixtrans-57.5-48.1166.2-59.3-32.7000109.7R398 T400 L401 S402 L407 T408 D409 L473R398-D405 IonicContact CZ-OD2 3.15Å; R398-D405 IonicContact NE-OD2 2.78Å; R398-D405 IonicContact NH2-OD1 2.69Å; R398-D405 PolarHBondContact NH2-OD1 3Å; R398-D405 IonicContact NH2-OD2 2.79Å; R398-D405 PolarHBondContact NH2-OD2 2.95Å; T400-D405 WeakPolarHBondContact CA-OD2 3.46Å; T400-D405 HydrophobicContact CG2-CB 3.64Å; L401-D405 PolarHBondContact N-OD2 3.04Å; S402-D405 PolarHBondContact N-OD2 3.46Å; S402-D405 WeakPolarHBondContact O-CB 3.23Å; S402-D405 PolarHBondContact O-N 3.31Å; S402-D405 PolarHBondContact OG-N 3.41Å; D405-L407 VanDerWaalsContact C-N 3.28Å; D405-L407 PolarHBondContact O-N 2.85Å; D405-T408 CarbonylContact O-C 3.57Å; D405-T408 WeakPolarHBondContact O-CA 3.37Å; D405-T408 WeakPolarHBondContact O-CB 3.47Å; D405-T408 PolarHBondContact O-N 2.98Å; D405-D409 PolarHBondContact O-N 2.9Å; D405-L473 HydrophobicContact CB-CD2 3.59Å
406A67.9Low76.9Confident22 Ų2237.7 Ų37.718%0.18220%0.2CC..Hα-helixtrans-62.1-33-179.200000113.1I218 T400 S402 K404 L410I218-A406 HydrophobicContact CD1-CB 4.42Å; T400-A406 HydrophobicContact CG2-CB 4.29Å; S402-A406 PolarHBondContact O-N 3.22Å; S402-A406 VanDerWaalsContact O-N 3.12Å; K404-A406 VanDerWaalsContact C-N 3.31Å; A406-L410 WeakPolarHBondContact O-CB 3.35Å; A406-L410 WeakPolarHBondContact O-CD1 3.48Å; A406-L410 WeakPolarHBondContact O-CG 3.35Å; A406-L410 PolarHBondContact O-N 2.85Å; A406-L410 VanDerWaalsContact O-N 3.08Å
407L60.6Low76.5Confident25 Ų2538.1 Ų38.113%0.13120%0.202CC..Hα-helixtrans-69.9-36171.2-175.658.1000111.9E217 L221 V377 P403 K404 D405 L410 T411E217-L407 HydrophobicContact CB-CD1 3.66Å; E217-L407 HydrophobicContact CB-CD2 4.27Å; E217-L407 HydrophobicContact CG-CD1 4.41Å; E217-L407 HydrophobicContact CG-CD2 4.34Å; L221-L407 HydrophobicContact CD1-CD1 4.33Å; V377-L407 HydrophobicContact CG1-CD2 4.18Å; V377-L407 HydrophobicContact CG1-CG 4.28Å; V377-L407 HydrophobicContact CG2-CD2 4.05Å; P403-L407 PolarHBondContact O-N 2.88Å; K404-L407 PolarHBondContact O-N 3.17Å; D405-L407 VanDerWaalsContact C-N 3.28Å; D405-L407 PolarHBondContact O-N 2.85Å; L407-L410 PolarHBondContact O-N 3.09Å; L407-T411 PolarHBondContact O-N 2.77Å; L407-T411 PolarHBondContact O-OG1 3.37Å
408T68.9Low75.9Confident0 Ų041 Ų410%022%0.221CC..Hα-helixtrans-65.1-40.6174.2-55.10000111.4Y378 K404 D405 T411 G431 L473Y378-T408 HydrophobicContact CD1-CG2 4Å; Y378-T408 PolarHBondContact N-OG1 3.43Å; Y378-T408 VanDerWaalsContact N-OG1 3.12Å; K404-T408 PolarHBondContact O-N 2.99Å; K404-T408 PolarHBondContact O-OG1 3.12Å; D405-T408 CarbonylContact O-C 3.57Å; D405-T408 WeakPolarHBondContact O-CA 3.37Å; D405-T408 WeakPolarHBondContact O-CB 3.47Å; D405-T408 PolarHBondContact O-N 2.98Å; T408-T411 WeakPolarHBondContact O-CB 3.38Å; T408-T411 PolarHBondContact O-N 2.83Å; T408-G431 WeakPolarHBondContact CG2-O 3.27Å; T408-L473 HydrophobicContact CG2-CD1 4.03Å
409D75.4Confident75.2Confident43 Ų4340.8 Ų40.823%0.2322%0.222CC..Hα-helixtrans-64.9-35.6173.3-74.2-42.2000113T400 D405 T411 H429 M432 L473T400-D409 WeakPolarHBondContact CB-OD2 3.47Å; T400-D409 WeakPolarHBondContact CG2-OD2 3.1Å; T400-D409 PolarHBondContact OG1-OD2 2.94Å; D405-D409 PolarHBondContact O-N 2.9Å; D409-T411 VanDerWaalsContact C-N 3.28Å; D409-T411 PolarHBondContact O-N 2.93Å; D409-H429 PolarHBondContact O-CE1 3.34Å; D409-H429 VanDerWaalsContact O-CE1 3.27Å; D409-H429 PolarHBondContact O-NE2 3.3Å; D409-M432 VanDerWaalsContact OD1-CE 3.22Å; D409-M432 WeakPolarHBondContact OD1-CE 3.19Å; D409-L473 WeakPolarHBondContact OD1-CB 3.45Å
410L67.6Low74.1Confident72 Ų7249.1 Ų49.138%0.37726%0.261SS..THydrogen-bonded Turntrans-82.1-2.4179.1-69.1168.7000113.8I218 L221 A406 L407 G412I218-L410 HydrophobicContact CG1-CD1 4.02Å; I218-L410 HydrophobicContact CG2-CD1 4.37Å; L221-L410 HydrophobicContact CD1-CB 3.93Å; L221-L410 HydrophobicContact CD1-CD1 4.22Å; A406-L410 WeakPolarHBondContact O-CB 3.35Å; A406-L410 WeakPolarHBondContact O-CD1 3.48Å; A406-L410 WeakPolarHBondContact O-CG 3.35Å; A406-L410 PolarHBondContact O-N 2.85Å; A406-L410 VanDerWaalsContact O-N 3.08Å; L407-L410 PolarHBondContact O-N 3.09Å; L410-G412 PolarHBondContact O-N 2.94Å
411T69.5Low73.2Confident20 Ų2050.1 Ų50.112%0.12328%0.28CS..  trans-78.866177.9-55.70000110.9Y378 L407 T408 D409 D413 H429 K430Y378-T411 HydrophobicContact CE1-CG2 4Å; L407-T411 PolarHBondContact O-N 2.77Å; L407-T411 PolarHBondContact O-OG1 3.37Å; T408-T411 WeakPolarHBondContact O-CB 3.38Å; T408-T411 PolarHBondContact O-N 2.83Å; D409-T411 VanDerWaalsContact C-N 3.28Å; D409-T411 PolarHBondContact O-N 2.93Å; T411-D413 PolarHBondContact O-N 3.11Å; T411-D413 VanDerWaalsContact O-N 3.1Å; T411-H429 PolarHBondContact O-CE1 3.42Å; T411-H429 VanDerWaalsContact O-CE1 3.3Å; T411-H429 PolarHBondContact O-NE2 3.42Å; T411-K430 HydrophobicContact CG2-CB 4.17Å; T411-K430 HydrophobicContact CG2-CD 4.09Å; T411-K430 HydrophobicContact CG2-CG 4.11Å
412G63.5Low72.7Confident17 Ų1750.5 Ų50.518%0.17528%0.28CS..  trans-70.51-166.900000117.8L410 H429 L531L410-G412 PolarHBondContact O-N 2.94Å; G412-H429 WeakPolarHBondContact CA-NE2 3.17Å; G412-L531 WeakPolarHBondContact O-CD1 3.4Å; G412-L531 WeakPolarHBondContact O-CG 3.4Å
413D77.1Confident72.1Confident87 Ų8758.5 Ų58.547%0.46532%0.315SS..  trans-57.8150.6172.5-76.9-21.7000111.5T411 K430T411-D413 PolarHBondContact O-N 3.11Å; T411-D413 VanDerWaalsContact O-N 3.1Å; D413-K430 HydrophobicContact CB-CB 3.84Å; D413-K430 HydrophobicContact CB-CD 3.41Å; D413-K430 VanDerWaalsContact CB-CD 3.41Å; D413-K430 HydrophobicContact CB-CG 4.33Å; D413-K430 VanDerWaalsContact O-CB 3.27Å; D413-K430 WeakPolarHBondContact O-CB 3.41Å; D413-K430 PolarHBondContact O-N 3.09Å; D413-K430 WeakPolarHBondContact OD2-CD 3.3Å; D413-K430 IonicContact OD2-NZ 3.96Å; D413-K430 PolarHBondContact OD2-NZ 3.17Å
414A85.4Confident72.3Confident42 Ų4258.4 Ų58.435%0.34732%0.319SS..EExtended strand (participates in β ladder)trans-91.5124.4166.900000110.2L427 L599A414-L427 HydrophobicContact CB-CB 4.31Å; A414-L427 HydrophobicContact CB-CD1 4.15Å; A414-L599 HydrophobicContact CB-CD1 4.17Å
415E88.7Confident72.7Confident71 Ų7160.3 Ų60.333%0.33234%0.335SS..EExtended strand (participates in β ladder)trans-113.3155.1177.6-17052.7-94.500110.8L427 G428 K430 V433E415-L427 CarbonylContact O-C 3.49Å; E415-L427 VanDerWaalsContact O-CA 3.26Å; E415-L427 WeakPolarHBondContact O-CA 3.34Å; E415-G428 PolarHBondContact N-O 2.78Å; E415-G428 PolarHBondContact O-N 3.38Å; E415-K430 HydrophobicContact CB-CB 3.76Å; E415-K430 HydrophobicContact CB-CG 3.93Å; E415-K430 HydrophobicContact CG-CG 4.35Å; E415-V433 HydrophobicContact CB-CB 4.38Å; E415-V433 HydrophobicContact CB-CG2 4.3Å; E415-V433 HydrophobicContact CG-CG1 4.26Å
416R90.1Very high73.5Confident165 Ų16561.3 Ų61.362%0.62334%0.339SS*.EExtended strand (participates in β ladder)trans-74.2136.6179.5-70179.7175.5-178.1-0.3111.4P418 L427R416-P418 WeakPolarHBondContact O-CD 3.28Å; R416-L427 HydrophobicContact CG-CD2 3.85Å
417L89.4Confident74.6Confident8 Ų861.7 Ų61.74%0.04234%0.338CS..  trans-74.6121175.5-78.2161.9000110.4V419 W426 V433 I480 L504 A508L417-V419 HydrophobicContact CB-CG2 4.28Å; L417-V419 PolarHBondContact O-N 2.9Å; L417-W426 HydrophobicContact CB-CB 4.18Å; L417-W426 HydrophobicContact CD1-CB 3.92Å; L417-W426 PolarHBondContact N-O 2.86Å; L417-V433 HydrophobicContact CD2-CG2 4.12Å; L417-I480 HydrophobicContact CD2-CB 4.38Å; L417-I480 HydrophobicContact CD2-CG1 4.2Å; L417-I480 HydrophobicContact CD2-CG2 3.48Å; L417-I480 VanDerWaalsContact CD2-CG2 3.48Å; L417-L504 HydrophobicContact CD1-CD2 4.02Å; L417-A508 HydrophobicContact CD1-CB 4.11Å
418P83.8Confident76.1Confident61 Ų6160.5 Ų60.540%0.39633%0.332SS..  trans-80.165-174.732.8-36.4000111.7R416 E437 L484R416-P418 WeakPolarHBondContact O-CD 3.28Å; P418-E437 HydrophobicContact CG-CG 3.85Å; P418-E437 WeakPolarHBondContact CG-OE1 3.38Å; P418-L484 HydrophobicContact CG-CD1 4.23Å; P418-L484 HydrophobicContact CG-CD2 3.77Å
419V81.4Confident77.2Confident21 Ų2161.3 Ų61.313%0.12734%0.335CS..  trans-110.4125.3-177.3-178.80000110L417 H422 W426 F483 L484L417-V419 HydrophobicContact CB-CG2 4.28Å; L417-V419 PolarHBondContact O-N 2.9Å; V419-H422 HydrophobicContact CB-CB 4.47Å; V419-H422 HydrophobicContact CG1-CB 4.42Å; V419-H422 PolarHBondContact O-N 3.2Å; V419-W426 HydrophobicContact CG1-CZ3 4.48Å; V419-F483 HydrophobicContact CG2-CB 3.93Å; V419-F483 HydrophobicContact CG2-CD1 4.49Å; V419-L484 HydrophobicContact CG2-CD2 3.91Å
420E67.9Low77.9Confident175 Ų17561.9 Ų61.982%0.81834%0.336SS*.THydrogen-bonded Turntrans-60.7144.6179-64.2-177.7177.100112.2H422E420-H422 PolarHBondContact O-N 2.79Å; E420-H422 PolarHBondContact O-ND1 3.17Å; E420-H422 VanDerWaalsContact O-ND1 3.13Å
421G63.8Low78.9Confident64 Ų6458.5 Ų58.566%0.6632%0.318SS*.THydrogen-bonded Turntrans73.7-17.9-177.900000116.1H423G421-H423 PolarHBondContact O-N 2.92Å
422H65.3Low80.1Confident75 Ų7557.6 Ų57.635%0.34731%0.313SS..  trans-100.285-178.5-65.874.8000109.8V419 E420 G424 W426V419-H422 HydrophobicContact CB-CB 4.47Å; V419-H422 HydrophobicContact CG1-CB 4.42Å; V419-H422 PolarHBondContact O-N 3.2Å; E420-H422 PolarHBondContact O-N 2.79Å; E420-H422 PolarHBondContact O-ND1 3.17Å; E420-H422 VanDerWaalsContact O-ND1 3.13Å; H422-G424 VanDerWaalsContact C-N 3.29Å; H422-G424 PolarHBondContact O-N 3.1Å; H422-W426 HydrophobicContact CB-CD2 4.49Å; H422-W426 HydrophobicContact CB-CE3 4.19Å; H422-W426 HydrophobicContact CB-CZ3 4.4Å; H422-W426 AromaticContact CD2-CE2 3.94Å; H422-W426 AromaticContact CD2-CE3 4Å; H422-W426 AromaticContact CD2-CH2 3.3Å; H422-W426 WeakPolarHBondContact CD2-CH2 3.41Å; H422-W426 AromaticContact CD2-CZ2 3.53Å; H422-W426 AromaticContact CD2-CZ3 3.55Å; H422-W426 AromaticContact CG-CZ3 3.83Å; H422-W426 AromaticContact NE2-CH2 3.42Å; H422-W426 WeakPolarHBondContact NE2-CH2 3.44Å; H422-W426 AromaticContact NE2-CZ2 3.91Å; H422-W426 AromaticContact NE2-CZ3 3.92Å
423H51.7Low81.5Confident183 Ų18356.9 Ų56.985%0.84730%0.304SS*.  trans-68.870.3-169.1-69.8-81.4000115.1G421 T425G421-H423 PolarHBondContact O-N 2.92Å; H423-T425 PolarHBondContact O-N 3.37Å
424G57.3Low82.3Confident26 Ų2655.1 Ų55.127%0.26830%0.295SS..SBendtrans78.99.715900000117.6H422H422-G424 VanDerWaalsContact C-N 3.29Å; H422-G424 PolarHBondContact O-N 3.1Å
425T78.1Confident82.7Confident89 Ų8953.1 Ų53.155%0.54628%0.278SS..  trans-82.1-28.4173.952.10000113.3H423H423-T425 PolarHBondContact O-N 3.37Å
426W90.4Very high83.1Confident21 Ų2149.8 Ų49.88%0.0826%0.263CS..  trans-84.9124.1-178.9-71.7-2.8000111.1L417 V419 H422 F483 A508 Y511L417-W426 HydrophobicContact CB-CB 4.18Å; L417-W426 HydrophobicContact CD1-CB 3.92Å; L417-W426 PolarHBondContact N-O 2.86Å; V419-W426 HydrophobicContact CG1-CZ3 4.48Å; H422-W426 HydrophobicContact CB-CD2 4.49Å; H422-W426 HydrophobicContact CB-CE3 4.19Å; H422-W426 HydrophobicContact CB-CZ3 4.4Å; H422-W426 AromaticContact CD2-CE2 3.94Å; H422-W426 AromaticContact CD2-CE3 4Å; H422-W426 AromaticContact CD2-CH2 3.3Å; H422-W426 WeakPolarHBondContact CD2-CH2 3.41Å; H422-W426 AromaticContact CD2-CZ2 3.53Å; H422-W426 AromaticContact CD2-CZ3 3.55Å; H422-W426 AromaticContact CG-CZ3 3.83Å; H422-W426 AromaticContact NE2-CH2 3.42Å; H422-W426 WeakPolarHBondContact NE2-CH2 3.44Å; H422-W426 AromaticContact NE2-CZ2 3.91Å; H422-W426 AromaticContact NE2-CZ3 3.92Å; W426-F483 HydrophobicContact CD2-CE1 4.48Å; W426-F483 AromaticContact CE3-CD1 3.88Å; W426-F483 HydrophobicContact CE3-CD1 3.88Å; W426-F483 AromaticContact CE3-CE1 3.79Å; W426-F483 HydrophobicContact CE3-CE1 3.79Å; W426-F483 HydrophobicContact CH2-CE1 4.41Å; W426-F483 AromaticContact CZ3-CD1 3.73Å; W426-F483 HydrophobicContact CZ3-CD1 3.73Å; W426-F483 AromaticContact CZ3-CE1 3.76Å; W426-F483 HydrophobicContact CZ3-CE1 3.76Å; W426-A508 HydrophobicContact CB-CB 4.1Å; W426-A508 HydrophobicContact CD2-CB 4.19Å; W426-A508 HydrophobicContact CG-CB 3.88Å; W426-Y511 AromaticContact CH2-CD1 3.33Å; W426-Y511 HydrophobicContact CH2-CD1 3.33Å; W426-Y511 AromaticContact CH2-CD2 3.84Å; W426-Y511 HydrophobicContact CH2-CD2 3.84Å; W426-Y511 AromaticContact CH2-CE1 3.63Å; W426-Y511 HydrophobicContact CH2-CE1 3.63Å; W426-Y511 HydrophobicContact CH2-CE2 4.11Å; W426-Y511 AromaticContact CH2-CG 3.43Å; W426-Y511 HydrophobicContact CH2-CG 3.43Å; W426-Y511 VanDerWaalsContact CH2-CG 3.43Å; W426-Y511 AromaticContact CH2-CZ 3.99Å; W426-Y511 HydrophobicContact CZ2-CD1 4.07Å; W426-Y511 HydrophobicContact CZ2-CD2 4.21Å; W426-Y511 AromaticContact CZ2-CG 3.78Å; W426-Y511 HydrophobicContact CZ2-CG 3.78Å; W426-Y511 AromaticContact CZ3-CD1 3.79Å; W426-Y511 HydrophobicContact CZ3-CD1 3.79Å; W426-Y511 AromaticContact CZ3-CE1 3.92Å; W426-Y511 HydrophobicContact CZ3-CE1 3.92Å; W426-Y511 HydrophobicContact CZ3-CG 4.33Å
427L91.3Very high83.3Confident31 Ų3145.7 Ų45.716%0.16225%0.251CS..EExtended strand (participates in β ladder)trans-116.9146.4179.8-53.4176.9000110.4A414 E415 R416 L504 S505 T597 L599A414-L427 HydrophobicContact CB-CB 4.31Å; A414-L427 HydrophobicContact CB-CD1 4.15Å; E415-L427 CarbonylContact O-C 3.49Å; E415-L427 VanDerWaalsContact O-CA 3.26Å; E415-L427 WeakPolarHBondContact O-CA 3.34Å; R416-L427 HydrophobicContact CG-CD2 3.85Å; L427-L504 WeakPolarHBondContact O-CA 3.23Å; L427-S505 PolarHBondContact N-OG 2.98Å; L427-S505 VanDerWaalsContact N-OG 3.08Å; L427-S505 PolarHBondContact O-N 3.4Å; L427-T597 HydrophobicContact CD1-CG2 4.35Å; L427-L599 HydrophobicContact CB-CD2 4.34Å
428G92.2Very high83.6Confident0 Ų047.2 Ų47.20%026%0.256CS..EExtended strand (participates in β ladder)trans-132.3161.8173.500000112E415 K430 L503E415-G428 PolarHBondContact N-O 2.78Å; E415-G428 PolarHBondContact O-N 3.38Å; G428-K430 PolarHBondContact O-N 2.88Å; G428-L503 CarbonylContact C-O 3.55Å; G428-L503 WeakPolarHBondContact CA-O 3.32Å
429H91.4Very high84.2Confident16 Ų1644.3 Ų44.37%0.07424%0.237CC..EExtended strand (participates in β ladder)trans-59117.3173.3-172.6-97.2000111D409 T411 G412 G431 M432 V433 L503D409-H429 PolarHBondContact O-CE1 3.34Å; D409-H429 VanDerWaalsContact O-CE1 3.27Å; D409-H429 PolarHBondContact O-NE2 3.3Å; T411-H429 PolarHBondContact O-CE1 3.42Å; T411-H429 VanDerWaalsContact O-CE1 3.3Å; T411-H429 PolarHBondContact O-NE2 3.42Å; G412-H429 WeakPolarHBondContact CA-NE2 3.17Å; H429-G431 PolarHBondContact O-N 3.36Å; H429-M432 HydrophobicContact CB-CB 4.42Å; H429-M432 HydrophobicContact CB-CG 4.48Å; H429-M432 CarbonylContact O-C 3.2Å; H429-M432 WeakPolarHBondContact O-CA 3.42Å; H429-M432 PolarHBondContact O-N 3.11Å; H429-V433 PolarHBondContact O-N 3.26Å; H429-L503 HydrophobicContact CB-CD1 4.1Å; H429-L503 PolarHBondContact N-O 3.08Å
430K89.4Confident84.9Confident56 Ų5645.8 Ų45.824%0.24324%0.242CC..Hα-helixtrans-52-47.8-167.3179.3174.7-175.9172.60114T411 D413 E415 G428 M432 V433 L434T411-K430 HydrophobicContact CG2-CB 4.17Å; T411-K430 HydrophobicContact CG2-CD 4.09Å; T411-K430 HydrophobicContact CG2-CG 4.11Å; D413-K430 HydrophobicContact CB-CB 3.84Å; D413-K430 HydrophobicContact CB-CD 3.41Å; D413-K430 VanDerWaalsContact CB-CD 3.41Å; D413-K430 HydrophobicContact CB-CG 4.33Å; D413-K430 VanDerWaalsContact O-CB 3.27Å; D413-K430 WeakPolarHBondContact O-CB 3.41Å; D413-K430 PolarHBondContact O-N 3.09Å; D413-K430 WeakPolarHBondContact OD2-CD 3.3Å; D413-K430 IonicContact OD2-NZ 3.96Å; D413-K430 PolarHBondContact OD2-NZ 3.17Å; E415-K430 HydrophobicContact CB-CB 3.76Å; E415-K430 HydrophobicContact CB-CG 3.93Å; E415-K430 HydrophobicContact CG-CG 4.35Å; G428-K430 PolarHBondContact O-N 2.88Å; K430-M432 PolarHBondContact O-N 2.99Å; K430-V433 PolarHBondContact O-N 2.94Å; K430-L434 HydrophobicContact CG-CD1 4.16Å; K430-L434 WeakPolarHBondContact O-CG 3.29Å; K430-L434 PolarHBondContact O-N 2.69Å
431G89.2Confident86.1Confident0 Ų043.1 Ų43.10%023%0.228CC..Hα-helixtrans-59.4-30.5178.400000113.8T408 H429 S435T408-G431 WeakPolarHBondContact CG2-O 3.27Å; H429-G431 PolarHBondContact O-N 3.36Å; G431-S435 WeakPolarHBondContact O-CB 3.33Å; G431-S435 PolarHBondContact O-N 3.02Å; G431-S435 PolarHBondContact O-OG 3.45Å
432M93.6Very high87.6Confident2 Ų241.1 Ų41.11%0.0120%0.201CC..Hα-helixtrans-92.1-25-178.1-57.9-175.3-167.100112.6D409 H429 K430 A436 L473 I480 P500 L503D409-M432 VanDerWaalsContact OD1-CE 3.22Å; D409-M432 WeakPolarHBondContact OD1-CE 3.19Å; H429-M432 HydrophobicContact CB-CB 4.42Å; H429-M432 HydrophobicContact CB-CG 4.48Å; H429-M432 CarbonylContact O-C 3.2Å; H429-M432 WeakPolarHBondContact O-CA 3.42Å; H429-M432 PolarHBondContact O-N 3.11Å; K430-M432 PolarHBondContact O-N 2.99Å; M432-A436 VanDerWaalsContact O-CB 3.31Å; M432-A436 WeakPolarHBondContact O-CB 3.27Å; M432-A436 PolarHBondContact O-N 3.42Å; M432-L473 HydrophobicContact CE-CD1 3.72Å; M432-L473 HydrophobicContact CG-CD1 3.74Å; M432-L473 HydrophobicContact SD-CD1 4.14Å; M432-I480 HydrophobicContact CB-CD1 3.77Å; M432-P500 HydrophobicContact CE-CG 3.8Å; M432-P500 HydrophobicContact SD-CG 3.77Å; M432-L503 HydrophobicContact CB-CD1 4.34Å; M432-L503 HydrophobicContact SD-CD1 3.63Å
433V94.2Very high89Confident1 Ų137.8 Ų37.81%0.00619%0.185CC..Hα-helixtrans-62.7-53.6165.6176.70000109.7E415 L417 H429 K430 S435 A436 E437 I480E415-V433 HydrophobicContact CB-CB 4.38Å; E415-V433 HydrophobicContact CB-CG2 4.3Å; E415-V433 HydrophobicContact CG-CG1 4.26Å; L417-V433 HydrophobicContact CD2-CG2 4.12Å; H429-V433 PolarHBondContact O-N 3.26Å; K430-V433 PolarHBondContact O-N 2.94Å; V433-S435 VanDerWaalsContact C-N 3.32Å; V433-S435 PolarHBondContact O-N 3.15Å; V433-A436 PolarHBondContact O-N 3.28Å; V433-E437 PolarHBondContact O-N 3.4Å; V433-I480 HydrophobicContact CG2-CD1 3.98Å; V433-I480 HydrophobicContact CG2-CG2 4.45Å
434L93.3Very high90.9Very high51 Ų5132.6 Ų32.627%0.26716%0.162SC..Hα-helixtrans-59.6-41.6178.9-64.8171.1000111.9Y378 K430 A436 E437 Y438Y378-L434 HydrophobicContact CD1-CB 4.11Å; Y378-L434 HydrophobicContact CD1-CD1 3.81Å; Y378-L434 HydrophobicContact CD2-CD1 4.06Å; Y378-L434 HydrophobicContact CE1-CD1 3.92Å; Y378-L434 HydrophobicContact CE2-CD1 4.15Å; Y378-L434 HydrophobicContact CG-CB 3.99Å; Y378-L434 HydrophobicContact CG-CD1 3.89Å; K430-L434 HydrophobicContact CG-CD1 4.16Å; K430-L434 WeakPolarHBondContact O-CG 3.29Å; K430-L434 PolarHBondContact O-N 2.69Å; L434-A436 VanDerWaalsContact C-N 3.33Å; L434-A436 PolarHBondContact O-N 2.91Å; L434-E437 PolarHBondContact O-N 2.8Å; L434-Y438 WeakPolarHBondContact O-CB 3.38Å; L434-Y438 PolarHBondContact O-N 2.93Å
435S94.3Very high92.6Very high0 Ų037.9 Ų37.90%018%0.18CC..Hα-helixtrans-63.5-35.6175.2-57.60000112.9Y378 T380 G431 V433 I439Y378-S435 WeakPolarHBondContact O-CA 3.37Å; T380-S435 PolarHBondContact OG1-OG 3.03Å; G431-S435 WeakPolarHBondContact O-CB 3.33Å; G431-S435 PolarHBondContact O-N 3.02Å; G431-S435 PolarHBondContact O-OG 3.45Å; V433-S435 VanDerWaalsContact C-N 3.32Å; V433-S435 PolarHBondContact O-N 3.15Å; S435-I439 VanDerWaalsContact O-CG1 3.31Å; S435-I439 WeakPolarHBondContact O-CG1 3.37Å; S435-I439 PolarHBondContact O-N 3.11Å; S435-I439 VanDerWaalsContact O-N 3.11Å
436A96.4Very high93.2Very high0 Ų036.6 Ų36.60%017%0.167CC..Hα-helixtrans-74.3-37.4176.700000112.3M432 V433 L434 I439 K440 T477 I480 L481 L484M432-A436 VanDerWaalsContact O-CB 3.31Å; M432-A436 WeakPolarHBondContact O-CB 3.27Å; M432-A436 PolarHBondContact O-N 3.42Å; V433-A436 PolarHBondContact O-N 3.28Å; L434-A436 VanDerWaalsContact C-N 3.33Å; L434-A436 PolarHBondContact O-N 2.91Å; A436-I439 PolarHBondContact O-N 3.32Å; A436-K440 WeakPolarHBondContact O-CB 3.41Å; A436-K440 PolarHBondContact O-N 3.38Å; A436-T477 HydrophobicContact CB-CG2 4.14Å; A436-I480 HydrophobicContact CB-CB 4.03Å; A436-I480 HydrophobicContact CB-CG2 3.61Å; A436-L481 HydrophobicContact CB-CB 4.04Å; A436-L484 HydrophobicContact CB-CD1 4.14Å
437E95.2Very high93.3Very high80 Ų8040.9 Ų40.937%0.37419%0.189SC..Hα-helixtrans-61.9-44171.6-71.4-171.112200111.6P418 V433 L434 K440 K441 L484P418-E437 HydrophobicContact CG-CG 3.85Å; P418-E437 WeakPolarHBondContact CG-OE1 3.38Å; V433-E437 PolarHBondContact O-N 3.4Å; L434-E437 PolarHBondContact O-N 2.8Å; E437-K440 PolarHBondContact O-N 3.03Å; E437-K441 VanDerWaalsContact O-CB 3.28Å; E437-K441 WeakPolarHBondContact O-CB 3.33Å; E437-K441 PolarHBondContact O-N 3.45Å; E437-L484 HydrophobicContact CG-CD1 4.36Å
438Y95.3Very high93.4Very high39 Ų3939.4 Ų39.415%0.15318%0.182CC..Hα-helixtrans-56.5-53.2174.5173.9-101.3000111.8E379 L434 K440 K441 K442E379-Y438 HydrophobicContact CB-CD1 4.1Å; E379-Y438 HydrophobicContact CB-CD2 4.36Å; E379-Y438 HydrophobicContact CB-CE1 3.77Å; E379-Y438 HydrophobicContact CB-CE2 4.03Å; E379-Y438 HydrophobicContact CB-CG 4.36Å; E379-Y438 HydrophobicContact CG-CD1 4.32Å; E379-Y438 HydrophobicContact CG-CD2 3.73Å; E379-Y438 HydrophobicContact CG-CE1 4.2Å; E379-Y438 HydrophobicContact CG-CE2 3.56Å; E379-Y438 HydrophobicContact CG-CG 4.08Å; E379-Y438 WeakPolarHBondContact OE2-CE2 3.46Å; E379-Y438 PolarHBondContact OE2-OH 3.38Å; L434-Y438 WeakPolarHBondContact O-CB 3.38Å; L434-Y438 PolarHBondContact O-N 2.93Å; Y438-K440 PolarHBondContact O-N 2.86Å; Y438-K441 PolarHBondContact O-N 2.95Å; Y438-K442 HydrophobicContact CE1-CG 4.17Å; Y438-K442 HydrophobicContact CE2-CG 4.25Å; Y438-K442 WeakPolarHBondContact O-CB 3.17Å; Y438-K442 PolarHBondContact O-N 2.82Å
439I96.1Very high93.4Very high0 Ų039.9 Ų39.90%018%0.184CC..Hα-helixtrans-63.8-41.9-179.3-65.7172.6000110.7F382 I397 S435 A436 K441 K442 L443 T477 L481F382-I439 HydrophobicContact CB-CD1 4.32Å; F382-I439 HydrophobicContact CD1-CB 4.49Å; F382-I439 HydrophobicContact CD1-CD1 4.08Å; F382-I439 HydrophobicContact CD1-CG1 3.74Å; F382-I439 HydrophobicContact CD1-CG2 4.14Å; F382-I439 HydrophobicContact CD2-CG2 4.15Å; F382-I439 HydrophobicContact CE1-CB 4.42Å; F382-I439 HydrophobicContact CE1-CG1 3.99Å; F382-I439 HydrophobicContact CE1-CG2 4.1Å; F382-I439 HydrophobicContact CE2-CG2 4.12Å; F382-I439 HydrophobicContact CG-CD1 4.32Å; F382-I439 HydrophobicContact CG-CG1 4.34Å; F382-I439 HydrophobicContact CG-CG2 4.16Å; F382-I439 HydrophobicContact CZ-CG2 4.09Å; I397-I439 HydrophobicContact CD1-CD1 3.82Å; I397-I439 HydrophobicContact CG1-CD1 4.12Å; I397-I439 HydrophobicContact CG2-CD1 3.78Å; S435-I439 VanDerWaalsContact O-CG1 3.31Å; S435-I439 WeakPolarHBondContact O-CG1 3.37Å; S435-I439 PolarHBondContact O-N 3.11Å; S435-I439 VanDerWaalsContact O-N 3.11Å; A436-I439 PolarHBondContact O-N 3.32Å; I439-K441 PolarHBondContact O-N 3.28Å; I439-K442 PolarHBondContact O-N 3.42Å; I439-L443 HydrophobicContact CG2-CD1 3.88Å; I439-L443 HydrophobicContact CG2-CG 4.21Å; I439-L443 WeakPolarHBondContact O-CB 3.46Å; I439-L443 WeakPolarHBondContact O-CG 3.5Å; I439-L443 PolarHBondContact O-N 2.75Å; I439-T477 HydrophobicContact CD1-CG2 3.95Å; I439-L481 HydrophobicContact CB-CD2 4.34Å; I439-L481 HydrophobicContact CG2-CD1 4.46Å; I439-L481 HydrophobicContact CG2-CD2 3.63Å
440K95.8Very high93.4Very high52 Ų5242.3 Ų42.323%0.22620%0.203CC..Hα-helixtrans-56.7-51.2173.8176.6176.8-178.8-67.20111.3A436 E437 Y438 K442 L443 E444 L481 L484A436-K440 WeakPolarHBondContact O-CB 3.41Å; A436-K440 PolarHBondContact O-N 3.38Å; E437-K440 PolarHBondContact O-N 3.03Å; Y438-K440 PolarHBondContact O-N 2.86Å; K440-K442 VanDerWaalsContact C-N 3.34Å; K440-K442 PolarHBondContact O-N 3.24Å; K440-L443 PolarHBondContact O-N 3.44Å; K440-E444 VanDerWaalsContact CE-OE1 3.32Å; K440-E444 WeakPolarHBondContact CE-OE1 3.5Å; K440-E444 IonicContact NZ-OE1 3.53Å; K440-E444 PolarHBondContact NZ-OE1 3.43Å; K440-E444 IonicContact NZ-OE2 3.86Å; K440-E444 PolarHBondContact NZ-OE2 3.05Å; K440-E444 WeakPolarHBondContact O-CG 3.21Å; K440-E444 PolarHBondContact O-N 3.01Å; K440-L481 HydrophobicContact CB-CD1 3.87Å; K440-L484 HydrophobicContact CD-CB 3.85Å; K440-L484 HydrophobicContact CD-CD1 4.24Å
441K94.8Very high93.5Very high119 Ų11943.1 Ų43.152%0.51721%0.207SC..Hα-helixtrans-58.9-43.6179.5178.4-177172.5-170.30111.5E437 Y438 I439 E444 Q445E437-K441 VanDerWaalsContact O-CB 3.28Å; E437-K441 WeakPolarHBondContact O-CB 3.33Å; E437-K441 PolarHBondContact O-N 3.45Å; Y438-K441 PolarHBondContact O-N 2.95Å; I439-K441 PolarHBondContact O-N 3.28Å; K441-E444 PolarHBondContact O-N 2.86Å; K441-Q445 HydrophobicContact CG-CG 4.22Å; K441-Q445 VanDerWaalsContact O-CB 3.3Å; K441-Q445 WeakPolarHBondContact O-CB 3.34Å; K441-Q445 VanDerWaalsContact O-CG 3.27Å; K441-Q445 WeakPolarHBondContact O-CG 3.29Å; K441-Q445 PolarHBondContact O-N 3.37Å
442K93.3Very high93.6Very high23 Ų2343.1 Ų43.110%0.121%0.207CC..Hα-helixtrans-59.7-49.9173.6-90-78-172.7164.20112.5E342 F382 Y438 I439 K440 E444 Q445 E446E342-K442 IonicContact OE1-NZ 3.27Å; E342-K442 PolarHBondContact OE1-NZ 3.09Å; E342-K442 IonicContact OE2-NZ 3.96Å; E342-K442 PolarHBondContact OE2-NZ 3.36Å; F382-K442 HydrophobicContact CE1-CB 4.29Å; F382-K442 HydrophobicContact CZ-CB 4.06Å; Y438-K442 HydrophobicContact CE1-CG 4.17Å; Y438-K442 HydrophobicContact CE2-CG 4.25Å; Y438-K442 WeakPolarHBondContact O-CB 3.17Å; Y438-K442 PolarHBondContact O-N 2.82Å; I439-K442 PolarHBondContact O-N 3.42Å; K440-K442 VanDerWaalsContact C-N 3.34Å; K440-K442 PolarHBondContact O-N 3.24Å; K442-E444 VanDerWaalsContact C-N 3.27Å; K442-E444 PolarHBondContact O-N 3.4Å; K442-Q445 PolarHBondContact O-N 2.88Å; K442-E446 WeakPolarHBondContact CD-OE1 3.32Å; K442-E446 WeakPolarHBondContact CE-OE1 3.44Å; K442-E446 IonicContact NZ-OE1 3.35Å; K442-E446 PolarHBondContact NZ-OE1 3.39Å; K442-E446 PolarHBondContact O-N 3.39Å
443L94.8Very high93.6Very high4 Ų444.4 Ų44.42%0.02121%0.213CC..Hα-helixtrans-59.5-36178.6-70.8170.8000112.7F382 V384 I395 I439 K440 M447 V448 L449 L481 L485F382-L443 HydrophobicContact CE2-CD2 3.8Å; F382-L443 HydrophobicContact CE2-CG 4.26Å; F382-L443 HydrophobicContact CZ-CD2 4.41Å; V384-L443 HydrophobicContact CG2-CD2 3.81Å; I395-L443 HydrophobicContact CD1-CD1 3.81Å; I395-L443 HydrophobicContact CG1-CD1 4.5Å; I439-L443 HydrophobicContact CG2-CD1 3.88Å; I439-L443 HydrophobicContact CG2-CG 4.21Å; I439-L443 WeakPolarHBondContact O-CB 3.46Å; I439-L443 WeakPolarHBondContact O-CG 3.5Å; I439-L443 PolarHBondContact O-N 2.75Å; K440-L443 PolarHBondContact O-N 3.44Å; L443-M447 CarbonylContact O-C 3.45Å; L443-M447 PolarHBondContact O-N 3.42Å; L443-V448 HydrophobicContact CD2-CB 3.77Å; L443-V448 HydrophobicContact CD2-CG1 3.88Å; L443-V448 HydrophobicContact CD2-CG2 4.36Å; L443-V448 PolarHBondContact O-N 2.98Å; L443-L449 HydrophobicContact CB-CG 4.46Å; L443-L449 HydrophobicContact CD2-CD2 4.23Å; L443-L449 HydrophobicContact CD2-CG 4.3Å; L443-L481 HydrophobicContact CD1-CD2 4.42Å; L443-L485 HydrophobicContact CD1-CD1 4.43Å
444E93.1Very high93.4Very high75 Ų7546.1 Ų46.135%0.3523%0.231SC..Hα-helixtrans-77.9-49.7177.4-71.4173.8151.200112.2K440 K441 K442 E446 M447 Q488K440-E444 VanDerWaalsContact CE-OE1 3.32Å; K440-E444 WeakPolarHBondContact CE-OE1 3.5Å; K440-E444 IonicContact NZ-OE1 3.53Å; K440-E444 PolarHBondContact NZ-OE1 3.43Å; K440-E444 IonicContact NZ-OE2 3.86Å; K440-E444 PolarHBondContact NZ-OE2 3.05Å; K440-E444 WeakPolarHBondContact O-CG 3.21Å; K440-E444 PolarHBondContact O-N 3.01Å; K441-E444 PolarHBondContact O-N 2.86Å; K442-E444 VanDerWaalsContact C-N 3.27Å; K442-E444 PolarHBondContact O-N 3.4Å; E444-E446 PolarHBondContact O-N 3.49Å; E444-M447 PolarHBondContact O-N 3.31Å; E444-Q488 PolarHBondContact OE1-NE2 2.97Å
445Q92.8Very high93Very high137 Ų13747 Ų4764%0.6423%0.231SC*.Hα-helixtrans-64.8-38.2-177-73.6-173.4-4800113.2K441 K442K441-Q445 HydrophobicContact CG-CG 4.22Å; K441-Q445 VanDerWaalsContact O-CB 3.3Å; K441-Q445 WeakPolarHBondContact O-CB 3.34Å; K441-Q445 VanDerWaalsContact O-CG 3.27Å; K441-Q445 WeakPolarHBondContact O-CG 3.29Å; K441-Q445 PolarHBondContact O-N 3.37Å; K442-Q445 PolarHBondContact O-N 2.88Å
446E90.4Very high92.5Very high62 Ų6249.4 Ų49.429%0.2924%0.244SC..THydrogen-bonded Turntrans-94.56.3178.1-66.8174.4-138.400112.4Y370 K442 E444 V448 Q451Y370-E446 WeakPolarHBondContact CE2-OE2 3.27Å; Y370-E446 PolarHBondContact OH-OE2 2.88Å; K442-E446 WeakPolarHBondContact CD-OE1 3.32Å; K442-E446 WeakPolarHBondContact CE-OE1 3.44Å; K442-E446 IonicContact NZ-OE1 3.35Å; K442-E446 PolarHBondContact NZ-OE1 3.39Å; K442-E446 PolarHBondContact O-N 3.39Å; E444-E446 PolarHBondContact O-N 3.49Å; E446-V448 HydrophobicContact CB-CG2 3.78Å; E446-V448 PolarHBondContact O-N 3.06Å; E446-V448 VanDerWaalsContact O-N 3.1Å; E446-Q451 PolarHBondContact O-NE2 3.27Å
447M91.7Very high92Very high110 Ų11055.1 Ų55.154%0.54227%0.273SS..THydrogen-bonded Turntrans53.729.7178-63.4-73-75.700113.5L443 E444 L449 S450 Q451L443-M447 CarbonylContact O-C 3.45Å; L443-M447 PolarHBondContact O-N 3.42Å; E444-M447 PolarHBondContact O-N 3.31Å; M447-L449 VanDerWaalsContact C-N 3.32Å; M447-L449 PolarHBondContact O-N 3.45Å; M447-S450 WeakPolarHBondContact O-CA 3.47Å; M447-S450 WeakPolarHBondContact O-CB 3.27Å; M447-S450 PolarHBondContact O-N 3.05Å; M447-Q451 PolarHBondContact O-N 3.18Å
448V93.4Very high91.4Very high0 Ų055 Ų550%029%0.294CS..Hα-helixtrans-59.2-40.8-167.6-179.20000112.1Y370 V384 L443 E446 Q451 A452Y370-V448 HydrophobicContact CD1-CG1 4.31Å; Y370-V448 HydrophobicContact CD2-CG1 4.11Å; Y370-V448 HydrophobicContact CD2-CG2 3.81Å; Y370-V448 HydrophobicContact CE2-CG2 3.95Å; Y370-V448 HydrophobicContact CG-CG1 3.73Å; Y370-V448 HydrophobicContact CG-CG2 4.11Å; V384-V448 HydrophobicContact CB-CG1 4.05Å; V384-V448 HydrophobicContact CG1-CG1 4.45Å; V384-V448 HydrophobicContact CG2-CG1 3.76Å; L443-V448 HydrophobicContact CD2-CB 3.77Å; L443-V448 HydrophobicContact CD2-CG1 3.88Å; L443-V448 HydrophobicContact CD2-CG2 4.36Å; L443-V448 PolarHBondContact O-N 2.98Å; E446-V448 HydrophobicContact CB-CG2 3.78Å; E446-V448 PolarHBondContact O-N 3.06Å; E446-V448 VanDerWaalsContact O-N 3.1Å; V448-Q451 WeakPolarHBondContact O-CB 3.31Å; V448-Q451 PolarHBondContact O-N 3.4Å; V448-A452 PolarHBondContact O-N 3.15Å
449L93.4Very high91Very high11 Ų1159.6 Ų59.66%0.05831%0.311CS..Hα-helixtrans-67.2-38.1177-62.8-178.1000111.7V393 I395 L443 M447 Q451 A452 F453 L466 Y489V393-L449 HydrophobicContact CG1-CD2 4.37Å; I395-L449 HydrophobicContact CD1-CD2 4.03Å; I395-L449 HydrophobicContact CG1-CD2 4.14Å; L443-L449 HydrophobicContact CB-CG 4.46Å; L443-L449 HydrophobicContact CD2-CD2 4.23Å; L443-L449 HydrophobicContact CD2-CG 4.3Å; M447-L449 VanDerWaalsContact C-N 3.32Å; M447-L449 PolarHBondContact O-N 3.45Å; L449-Q451 VanDerWaalsContact C-N 3.32Å; L449-Q451 PolarHBondContact O-N 3.4Å; L449-A452 PolarHBondContact O-N 3.5Å; L449-F453 HydrophobicContact CB-CD2 4.28Å; L449-F453 HydrophobicContact CB-CE2 4.15Å; L449-F453 WeakPolarHBondContact O-CD2 3.42Å; L449-F453 PolarHBondContact O-N 2.88Å; L449-L466 HydrophobicContact CD1-CD2 4.33Å; L449-L466 HydrophobicContact CD2-CD1 4.27Å; L449-Y489 HydrophobicContact CD1-CE2 3.95Å
450S91.4Very high90.6Very high66 Ų6660.8 Ų60.846%0.46232%0.323SS..Hα-helixtrans-64.1-37.7174.1-50.40000111.9M447 G454M447-S450 WeakPolarHBondContact O-CA 3.47Å; M447-S450 WeakPolarHBondContact O-CB 3.27Å; M447-S450 PolarHBondContact O-N 3.05Å; S450-G454 PolarHBondContact O-N 3.42Å
451Q91.3Very high90.3Very high73 Ų7358.3 Ų58.334%0.34131%0.312SS..Hα-helixtrans-63.7-43.6172.4-61.4-177.54600111.6V369 E446 M447 V448 L449 G454 R455V369-Q451 HydrophobicContact CG1-CB 4.06Å; E446-Q451 PolarHBondContact O-NE2 3.27Å; M447-Q451 PolarHBondContact O-N 3.18Å; V448-Q451 WeakPolarHBondContact O-CB 3.31Å; V448-Q451 PolarHBondContact O-N 3.4Å; L449-Q451 VanDerWaalsContact C-N 3.32Å; L449-Q451 PolarHBondContact O-N 3.4Å; Q451-G454 CarbonylContact O-C 3.59Å; Q451-G454 PolarHBondContact O-N 3.45Å; Q451-R455 PolarHBondContact O-N 3.2Å; Q451-R455 VanDerWaalsContact O-N 3.09Å
452A92.1Very high90.1Very high0 Ų060 Ų600%032%0.319CS..Hα-helixtrans-67.9-47.8179.800000113V369 V384 V386 V393 V448 L449 G454 R455V369-A452 HydrophobicContact CG1-CB 4.43Å; V369-A452 HydrophobicContact CG2-CB 4.38Å; V384-A452 HydrophobicContact CG1-CB 4.18Å; V386-A452 HydrophobicContact CG2-CB 4Å; V393-A452 HydrophobicContact CG1-CB 3.74Å; V393-A452 HydrophobicContact CG2-CB 4.1Å; V448-A452 PolarHBondContact O-N 3.15Å; L449-A452 PolarHBondContact O-N 3.5Å; A452-G454 PolarHBondContact O-N 3.22Å; A452-R455 VanDerWaalsContact O-CB 3.27Å; A452-R455 WeakPolarHBondContact O-CB 3.3Å; A452-R455 PolarHBondContact O-N 2.83Å
453F93.4Very high90Very high29 Ų2966.7 Ų66.713%0.12735%0.351CS..Hα-helixtrans-67.6-23174.6-68.1-60.9000112.8V393 L449 T461 K462 Y464 L466 Y489V393-F453 HydrophobicContact CB-CE1 4Å; V393-F453 HydrophobicContact CB-CZ 4.16Å; V393-F453 HydrophobicContact CG2-CD1 3.55Å; V393-F453 HydrophobicContact CG2-CE1 3.39Å; V393-F453 HydrophobicContact CG2-CG 4.23Å; V393-F453 HydrophobicContact CG2-CZ 3.96Å; L449-F453 HydrophobicContact CB-CD2 4.28Å; L449-F453 HydrophobicContact CB-CE2 4.15Å; L449-F453 WeakPolarHBondContact O-CD2 3.42Å; L449-F453 PolarHBondContact O-N 2.88Å; F453-T461 CarbonylContact O-C 3.58Å; F453-T461 VanDerWaalsContact O-C 3.28Å; F453-T461 VanDerWaalsContact O-CB 3.26Å; F453-T461 WeakPolarHBondContact O-CB 3.03Å; F453-T461 PolarHBondContact O-OG1 3.06Å; F453-K462 PolarHBondContact O-N 3.35Å; F453-K462 VanDerWaalsContact O-N 3.12Å; F453-Y464 WeakPolarHBondContact CE1-O 3.47Å; F453-L466 HydrophobicContact CZ-CB 4.4Å; F453-L466 HydrophobicContact CZ-CD1 4.44Å; F453-Y489 HydrophobicContact CD2-CE1 4.43Å; F453-Y489 HydrophobicContact CE2-CD1 4.38Å; F453-Y489 AromaticContact CE2-CE1 3.47Å; F453-Y489 HydrophobicContact CE2-CE1 3.47Å; F453-Y489 VanDerWaalsContact CE2-CE1 3.47Å; F453-Y489 AromaticContact CE2-CZ 3.92Å; F453-Y489 HydrophobicContact CZ-CD1 4.31Å; F453-Y489 AromaticContact CZ-CE1 3.81Å; F453-Y489 HydrophobicContact CZ-CE1 3.81Å
454G89.7Confident90Very high37 Ų3767.4 Ų67.438%0.38135%0.353SS..THydrogen-bonded Turntrans-85.4-7.1173.700000115.6S450 Q451 A452 D456S450-G454 PolarHBondContact O-N 3.42Å; Q451-G454 CarbonylContact O-C 3.59Å; Q451-G454 PolarHBondContact O-N 3.45Å; A452-G454 PolarHBondContact O-N 3.22Å; G454-D456 PolarHBondContact O-N 2.93Å
455R84.6Confident90.1Very high70 Ų7064.4 Ų64.426%0.26434%0.343SS..THydrogen-bonded Turntrans-61.2-40.8-164.6-170.864.2175.2165.64.6114.9P337 G338 V369 V386 Q451 A452P337-R455 PolarHBondContact O-NH1 3.07Å; P337-R455 PolarHBondContact O-NH2 3.41Å; P337-R455 VanDerWaalsContact O-NH2 3.15Å; G338-R455 PolarHBondContact O-NH1 3.13Å; V369-R455 HydrophobicContact CG2-CG 4.15Å; V386-R455 HydrophobicContact CG2-CB 4.24Å; Q451-R455 PolarHBondContact O-N 3.2Å; Q451-R455 VanDerWaalsContact O-N 3.09Å; A452-R455 VanDerWaalsContact O-CB 3.27Å; A452-R455 WeakPolarHBondContact O-CB 3.3Å; A452-R455 PolarHBondContact O-N 2.83Å
456D84.1Confident90.4Very high51 Ų5158 Ų5827%0.27331%0.313SS..THydrogen-bonded Turntrans-144.486.2174-171.9-21.2000110.2G454 G458 R459 G460 T461G454-D456 PolarHBondContact O-N 2.93Å; D456-G458 PolarHBondContact O-N 3.03Å; D456-G458 WeakPolarHBondContact OD1-CA 3.49Å; D456-G458 PolarHBondContact OD1-N 3.01Å; D456-R459 HydrophobicContact CB-CB 4.18Å; D456-R459 HydrophobicContact CB-CG 4.43Å; D456-R459 PolarHBondContact O-N 3.18Å; D456-R459 PolarHBondContact OD1-N 3.35Å; D456-R459 WeakPolarHBondContact OD2-CD 3.37Å; D456-R459 WeakPolarHBondContact OD2-CG 3.32Å; D456-R459 IonicContact OD2-CZ 3.94Å; D456-R459 IonicContact OD2-NE 3.18Å; D456-R459 PolarHBondContact OD2-NE 3.3Å; D456-G460 PolarHBondContact O-N 2.92Å; D456-T461 HydrophobicContact CB-CG2 3.98Å; D456-T461 PolarHBondContact N-OG1 3.33Å; D456-T461 WeakPolarHBondContact O-CG2 3.35Å; D456-T461 PolarHBondContact O-N 3.1Å; D456-T461 VanDerWaalsContact O-N 3.1Å; D456-T461 PolarHBondContact O-OG1 3.1Å
457L85.3Confident90.8Very high119 Ų11955.3 Ų55.362%0.62330%0.3SS*.THydrogen-bonded Turntrans-61.9-24.5176-62.3178.4000112.7G460 K462L457-G460 PolarHBondContact O-N 3.47Å; L457-G460 VanDerWaalsContact O-N 3.12Å; L457-K462 HydrophobicContact CD2-CB 4.33Å
458G83.3Confident91.1Very high78 Ų7850 Ų5080%0.80428%0.275SS*.THydrogen-bonded Turntrans-70.1-36.2175.700000112.7D456 G460D456-G458 PolarHBondContact O-N 3.03Å; D456-G458 WeakPolarHBondContact OD1-CA 3.49Å; D456-G458 PolarHBondContact OD1-N 3.01Å; G458-G460 PolarHBondContact O-N 2.95Å
459R86.1Confident91.3Very high136 Ų13650 Ų5051%0.51328%0.275SS..THydrogen-bonded Turntrans-81.22.8168.3-68178.2-172.6-174.9-2.7113.7H388 D456 Y464H388-R459 PolarHBondContact CD2-NH1 3Å; H388-R459 VanDerWaalsContact CG-NH1 3.33Å; H388-R459 WeakPolarHBondContact ND1-CD 3.37Å; D456-R459 HydrophobicContact CB-CB 4.18Å; D456-R459 HydrophobicContact CB-CG 4.43Å; D456-R459 PolarHBondContact O-N 3.18Å; D456-R459 PolarHBondContact OD1-N 3.35Å; D456-R459 WeakPolarHBondContact OD2-CD 3.37Å; D456-R459 WeakPolarHBondContact OD2-CG 3.32Å; D456-R459 IonicContact OD2-CZ 3.94Å; D456-R459 IonicContact OD2-NE 3.18Å; D456-R459 PolarHBondContact OD2-NE 3.3Å; R459-Y464 PolarHBondContact O-OH 3.03Å
460G88.1Confident91.5Very high24 Ų2449.5 Ų49.525%0.24727%0.272CS..THydrogen-bonded Turntrans69.534178.200000114.4D456 L457 G458 K462 H463 Y464D456-G460 PolarHBondContact O-N 2.92Å; L457-G460 PolarHBondContact O-N 3.47Å; L457-G460 VanDerWaalsContact O-N 3.12Å; G458-G460 PolarHBondContact O-N 2.95Å; G460-K462 PolarHBondContact O-N 2.87Å; G460-H463 PolarHBondContact O-N 2.84Å; G460-Y464 WeakPolarHBondContact O-CD1 3.43Å
461T89.5Confident91.8Very high0 Ų046.4 Ų46.40%025%0.25CS..G310 helixtrans-52.1-28.5-178.948.90000113.9V386 F453 D456 H463 Y464V386-T461 HydrophobicContact CG1-CG2 4.03Å; F453-T461 CarbonylContact O-C 3.58Å; F453-T461 VanDerWaalsContact O-C 3.28Å; F453-T461 VanDerWaalsContact O-CB 3.26Å; F453-T461 WeakPolarHBondContact O-CB 3.03Å; F453-T461 PolarHBondContact O-OG1 3.06Å; D456-T461 HydrophobicContact CB-CG2 3.98Å; D456-T461 PolarHBondContact N-OG1 3.33Å; D456-T461 WeakPolarHBondContact O-CG2 3.35Å; D456-T461 PolarHBondContact O-N 3.1Å; D456-T461 VanDerWaalsContact O-N 3.1Å; D456-T461 PolarHBondContact O-OG1 3.1Å; T461-H463 PolarHBondContact O-N 3.16Å; T461-Y464 HydrophobicContact CG2-CD2 4.21Å; T461-Y464 HydrophobicContact CG2-CE1 4.39Å; T461-Y464 HydrophobicContact CG2-CE2 3.76Å; T461-Y464 WeakPolarHBondContact O-CB 3.42Å; T461-Y464 PolarHBondContact O-N 2.91Å
462K90.3Very high92Very high154 Ų15443.2 Ų43.267%0.6724%0.236SC*.G310 helixtrans-55.9-21.3174.5-173.3174.6179.5-179.50114.4F453 L457 G460F453-K462 PolarHBondContact O-N 3.35Å; F453-K462 VanDerWaalsContact O-N 3.12Å; L457-K462 HydrophobicContact CD2-CB 4.33Å; G460-K462 PolarHBondContact O-N 2.87Å
463H91.1Very high92Very high165 Ų16543.2 Ų43.276%0.76424%0.236SC*.G310 helixtrans-106.112.6179.8-59.5-69.6000113.5G460 T461G460-H463 PolarHBondContact O-N 2.84Å; T461-H463 PolarHBondContact O-N 3.16Å
464Y95.4Very high92.2Very high18 Ų1841.9 Ų41.97%0.07123%0.23CC..PPolyproline II helixtrans-75.3150.4179.7-74.419.4000110.6V386 H388 K391 F453 R459 G460 T461V386-Y464 HydrophobicContact CG1-CD2 3.94Å; V386-Y464 HydrophobicContact CG1-CE2 3.75Å; H388-Y464 AromaticContact ND1-CE2 3.61Å; H388-Y464 AromaticContact ND1-CZ 3.68Å; H388-Y464 PolarHBondContact ND1-OH 2.8Å; K391-Y464 VanDerWaalsContact C-CD2 3.42Å; K391-Y464 HydrophobicContact CB-CD1 3.67Å; K391-Y464 HydrophobicContact CB-CD2 4.34Å; K391-Y464 HydrophobicContact CB-CE1 3.74Å; K391-Y464 HydrophobicContact CB-CE2 4.38Å; K391-Y464 HydrophobicContact CB-CG 4.01Å; K391-Y464 HydrophobicContact CD-CE1 4.26Å; K391-Y464 HydrophobicContact CG-CD1 4.31Å; K391-Y464 HydrophobicContact CG-CE1 3.86Å; K391-Y464 VanDerWaalsContact O-CA 3.31Å; K391-Y464 WeakPolarHBondContact O-CA 3.37Å; K391-Y464 VanDerWaalsContact O-CB 3.32Å; K391-Y464 WeakPolarHBondContact O-CB 3.13Å; F453-Y464 WeakPolarHBondContact CE1-O 3.47Å; R459-Y464 PolarHBondContact O-OH 3.03Å; G460-Y464 WeakPolarHBondContact O-CD1 3.43Å; T461-Y464 HydrophobicContact CG2-CD2 4.21Å; T461-Y464 HydrophobicContact CG2-CE1 4.39Å; T461-Y464 HydrophobicContact CG2-CE2 3.76Å; T461-Y464 WeakPolarHBondContact O-CB 3.42Å; T461-Y464 PolarHBondContact O-N 2.91Å
465G96Very high92.6Very high13 Ų1340.1 Ų40.113%0.13421%0.212CC..EExtended strand (participates in β ladder)trans-83150.7175.500000111.9K391 K392 V393K391-G465 PolarHBondContact O-N 3.25Å; K392-G465 CarbonylContact C-O 3.5Å; K392-G465 WeakPolarHBondContact CA-O 3.46Å; K392-G465 WeakPolarHBondContact CD-O 3.47Å; V393-G465 PolarHBondContact N-O 3.38Å
466L97.8Very high93.1Very high3 Ų336.8 Ų36.82%0.01620%0.199CC..EExtended strand (participates in β ladder)trans-89.6133.5175.8-169.251.9000111.1V393 I395 L449 F453 L485 Y489 L492 K493V393-L466 HydrophobicContact CB-CD1 4.02Å; V393-L466 HydrophobicContact CG1-CD1 3.97Å; I395-L466 HydrophobicContact CD1-CD1 3.96Å; I395-L466 HydrophobicContact CD1-CD2 4.43Å; I395-L466 HydrophobicContact CD1-CG 4.49Å; I395-L466 HydrophobicContact CG1-CD1 4.12Å; L449-L466 HydrophobicContact CD1-CD2 4.33Å; L449-L466 HydrophobicContact CD2-CD1 4.27Å; F453-L466 HydrophobicContact CZ-CB 4.4Å; F453-L466 HydrophobicContact CZ-CD1 4.44Å; L466-L485 HydrophobicContact CD2-CD1 4.32Å; L466-Y489 HydrophobicContact CB-CD1 4.44Å; L466-Y489 HydrophobicContact CD2-CD1 3.98Å; L466-Y489 HydrophobicContact CD2-CD2 3.68Å; L466-Y489 HydrophobicContact CD2-CE1 4.35Å; L466-Y489 HydrophobicContact CD2-CE2 4.1Å; L466-Y489 HydrophobicContact CD2-CG 3.63Å; L466-L492 HydrophobicContact CD2-CD1 4.01Å; L466-L492 HydrophobicContact CG-CD1 4.16Å; L466-L492 WeakPolarHBondContact O-CA 3.48Å; L466-K493 PolarHBondContact O-N 2.95Å
467I98.4Very high93.7Very high4 Ų434.3 Ų34.32%0.02119%0.186CC..EExtended strand (participates in β ladder)trans-121.5135.9172-56.2-60.7000108.1Y295 K392 V393 V394 I395 K493 F495Y295-I467 HydrophobicContact CD1-CG2 4.19Å; Y295-I467 HydrophobicContact CE1-CG1 4.23Å; Y295-I467 HydrophobicContact CE1-CG2 4.26Å; Y295-I467 HydrophobicContact CG-CG2 4.5Å; K392-I467 HydrophobicContact CB-CG1 3.98Å; K392-I467 HydrophobicContact CD-CD1 4.11Å; K392-I467 HydrophobicContact CD-CG1 3.92Å; K392-I467 HydrophobicContact CG-CD1 4.44Å; K392-I467 HydrophobicContact CG-CG1 3.84Å; V393-I467 PolarHBondContact O-N 2.95Å; V394-I467 WeakPolarHBondContact CA-O 3.29Å; V394-I467 HydrophobicContact CG1-CB 4.4Å; V394-I467 HydrophobicContact CG1-CG2 4.32Å; V394-I467 HydrophobicContact CG2-CB 4.25Å; I395-I467 PolarHBondContact N-O 3.27Å; I467-K493 WeakPolarHBondContact CA-O 3.45Å; I467-K493 HydrophobicContact CD1-CB 3.95Å; I467-K493 HydrophobicContact CD1-CD 4.44Å; I467-F495 HydrophobicContact CD1-CE2 4.39Å; I467-F495 HydrophobicContact CG2-CD2 3.89Å; I467-F495 HydrophobicContact CG2-CE2 4.23Å
468V98.6Very high94.4Very high0 Ų028.7 Ų28.70%016%0.156CC..EExtended strand (participates in β ladder)trans-111.1140.5165.9-160.40000108.4I395 I397 A478 L481 S482 L492 K493 C494 F495I395-V468 HydrophobicContact CB-CG1 4.31Å; I395-V468 HydrophobicContact CD1-CG2 4.35Å; I395-V468 HydrophobicContact CG2-CG1 4.47Å; I395-V468 CarbonylContact O-C 2.92Å; I395-V468 WeakPolarHBondContact O-CA 3.48Å; I397-V468 HydrophobicContact CD1-CG1 4.3Å; V468-A478 HydrophobicContact CG1-CB 3.7Å; V468-L481 HydrophobicContact CG1-CD2 4.1Å; V468-S482 WeakPolarHBondContact CB-OG 3.5Å; V468-S482 WeakPolarHBondContact CG2-OG 3.41Å; V468-L492 HydrophobicContact CG2-CD1 3.83Å; V468-L492 HydrophobicContact CG2-CD2 4.18Å; V468-L492 HydrophobicContact CG2-CG 4.16Å; V468-K493 PolarHBondContact N-O 3.44Å; V468-C494 VanDerWaalsContact O-CA 3.28Å; V468-C494 WeakPolarHBondContact O-CA 3.46Å; V468-F495 PolarHBondContact O-N 3.22Å
469V98.5Very high95Very high0 Ų025 Ų250%012%0.118CC..EExtended strand (participates in β ladder)trans-147.8147.2-176.268.40000111.7F298 A299 V394 I395 S396 I397 F495 Y497F298-V469 HydrophobicContact CB-CG1 3.84Å; A299-V469 HydrophobicContact CB-CG2 4.08Å; V394-V469 HydrophobicContact CG1-CG1 3.63Å; I395-V469 WeakPolarHBondContact O-CG1 3.47Å; I395-V469 PolarHBondContact O-N 2.92Å; S396-V469 WeakPolarHBondContact CA-O 3.38Å; I397-V469 PolarHBondContact N-O 2.85Å; V469-F495 WeakPolarHBondContact CA-O 3.39Å; V469-F495 HydrophobicContact CG2-CB 4.09Å; V469-Y497 HydrophobicContact CG2-CD2 4.24Å; V469-Y497 HydrophobicContact CG2-CE2 3.64Å
470G97.8Very high95.6Very high0 Ų018.5 Ų18.50%09%0.094CC..EExtended strand (participates in β ladder)trans-174170.7175.600000112.8A475 F495 Y497G470-A475 WeakPolarHBondContact O-CB 3.41Å; G470-F495 PolarHBondContact N-O 2.86Å; G470-Y497 WeakPolarHBondContact O-CD2 3.47Å; G470-Y497 PolarHBondContact O-N 3.49Å
471H97Very high96Very high1 Ų117.3 Ų17.31%0.0058%0.082CC..EExtended strand (participates in β ladder)trans-125.6142.9179.7177.8-95.7000110.8A299 Y303 G399 L473 G474 A475 Y497 H650A299-H471 HydrophobicContact CB-CB 4.37Å; Y303-H471 HydrophobicContact CE2-CB 4.17Å; Y303-H471 AromaticContact CZ-ND1 3.9Å; Y303-H471 PolarHBondContact OH-ND1 2.73Å; G399-H471 WeakPolarHBondContact CA-O 3.39Å; H471-L473 PolarHBondContact O-N 3.34Å; H471-G474 WeakPolarHBondContact O-CA 3.38Å; H471-G474 PolarHBondContact O-N 3.1Å; H471-A475 PolarHBondContact O-N 3.35Å; H471-Y497 CarbonylContact C-O 3.5Å; H471-Y497 VanDerWaalsContact CA-O 3.3Å; H471-Y497 WeakPolarHBondContact CA-O 3.46Å; H471-Y497 PolarHBondContact CD2-O 3.15Å; H471-H650 AromaticContact CE1-CE1 3.83Å; H471-H650 AromaticContact CE1-NE2 3.72Å; H471-H650 PolarHBondContact CE1-O 3.08Å; H471-H650 PolarHBondContact NE2-O 3.25Å
472S94.9Very high96.4Very high6 Ų617.3 Ų17.34%0.0428%0.082CC..THydrogen-bonded Turntrans55.7-126.6178.2-164.80000112.5G474 A475 G476 Y497 S498 H650S472-G474 PolarHBondContact O-N 3.1Å; S472-A475 WeakPolarHBondContact O-CA 3.29Å; S472-A475 VanDerWaalsContact O-CB 3.26Å; S472-A475 WeakPolarHBondContact O-CB 3.33Å; S472-A475 PolarHBondContact O-N 2.91Å; S472-G476 PolarHBondContact O-N 3.07Å; S472-G476 VanDerWaalsContact O-N 3.12Å; S472-Y497 PolarHBondContact N-O 3.07Å; S472-S498 WeakPolarHBondContact CA-O 3.27Å; S472-H650 WeakPolarHBondContact CB-NE2 3.37Å; S472-H650 PolarHBondContact OG-CE1 3.48Å; S472-H650 PolarHBondContact OG-NE2 2.67Å
473L93.4Very high96.6Very high0 Ų010.1 Ų10.10%05%0.051CC..Hα-helixtrans-38.1-52.9164.8171.155.8000112.5T380 T400 D405 T408 D409 M432 H471 A475 G476 T477T380-L473 HydrophobicContact CG2-CD2 4.21Å; T380-L473 HydrophobicContact CG2-CG 4.46Å; T400-L473 WeakPolarHBondContact OG1-CB 3.31Å; D405-L473 HydrophobicContact CB-CD2 3.59Å; T408-L473 HydrophobicContact CG2-CD1 4.03Å; D409-L473 WeakPolarHBondContact OD1-CB 3.45Å; M432-L473 HydrophobicContact CE-CD1 3.72Å; M432-L473 HydrophobicContact CG-CD1 3.74Å; M432-L473 HydrophobicContact SD-CD1 4.14Å; H471-L473 PolarHBondContact O-N 3.34Å; L473-A475 VanDerWaalsContact C-N 3.26Å; L473-A475 PolarHBondContact O-N 3.44Å; L473-G476 PolarHBondContact O-N 2.9Å; L473-G476 VanDerWaalsContact O-N 3.11Å; L473-T477 PolarHBondContact O-N 2.95Å; L473-T477 PolarHBondContact O-OG1 3.12Å
474G96.3Very high96.8Very high0 Ų02.9 Ų2.90%02%0.017CC..Hα-helixtrans-64.6-26.9-179.500000113.4R398 H471 S472 A478R398-G474 VanDerWaalsContact O-CA 3.25Å; R398-G474 WeakPolarHBondContact O-CA 3.2Å; R398-G474 PolarHBondContact O-N 3.15Å; H471-G474 WeakPolarHBondContact O-CA 3.38Å; H471-G474 PolarHBondContact O-N 3.1Å; S472-G474 PolarHBondContact O-N 3.1Å; G474-A478 WeakPolarHBondContact O-CB 3.28Å; G474-A478 PolarHBondContact O-N 3.41Å
475A97.6Very high96.8Very high0 Ų02 Ų20%01%0.014CC..Hα-helixtrans-73.1-38.3173.600000111.7G470 H471 S472 L473 A479 A496 Y497 P499G470-A475 WeakPolarHBondContact O-CB 3.41Å; H471-A475 PolarHBondContact O-N 3.35Å; S472-A475 WeakPolarHBondContact O-CA 3.29Å; S472-A475 VanDerWaalsContact O-CB 3.26Å; S472-A475 WeakPolarHBondContact O-CB 3.33Å; S472-A475 PolarHBondContact O-N 2.91Å; L473-A475 VanDerWaalsContact C-N 3.26Å; L473-A475 PolarHBondContact O-N 3.44Å; A475-A479 WeakPolarHBondContact O-CB 3.46Å; A475-A479 PolarHBondContact O-N 3.08Å; A475-A496 HydrophobicContact CB-CB 4.01Å; A475-Y497 VanDerWaalsContact CB-O 3.31Å; A475-Y497 WeakPolarHBondContact CB-O 3.39Å; A475-P499 HydrophobicContact CB-CB 3.94Å
476G96.1Very high96.6Very high0 Ų03.2 Ų3.20%02%0.015CC..Hα-helixtrans-65.9-50.9173.400000112S472 L473 A478 A479 I480S472-G476 PolarHBondContact O-N 3.07Å; S472-G476 VanDerWaalsContact O-N 3.12Å; L473-G476 PolarHBondContact O-N 2.9Å; L473-G476 VanDerWaalsContact O-N 3.11Å; G476-A478 VanDerWaalsContact C-N 3.32Å; G476-A478 PolarHBondContact O-N 2.94Å; G476-A479 PolarHBondContact O-N 3.01Å; G476-I480 PolarHBondContact O-N 3.23Å
477T97.3Very high96.3Very high0 Ų07 Ų70%04%0.04CC..Hα-helixtrans-60.5-38.9174.7-55.60000111.8I397 A436 I439 L473 I480 L481I397-T477 HydrophobicContact CD1-CG2 3.99Å; I397-T477 HydrophobicContact CG2-CG2 4.36Å; A436-T477 HydrophobicContact CB-CG2 4.14Å; I439-T477 HydrophobicContact CD1-CG2 3.95Å; L473-T477 PolarHBondContact O-N 2.95Å; L473-T477 PolarHBondContact O-OG1 3.12Å; T477-I480 PolarHBondContact O-N 3.38Å; T477-L481 VanDerWaalsContact O-CB 3.23Å; T477-L481 WeakPolarHBondContact O-CB 3.24Å; T477-L481 PolarHBondContact O-N 2.89Å
478A98.1Very high95.9Very high0 Ų011.7 Ų11.70%06%0.061CC..Hα-helixtrans-64.9-41.9175.200000112.6I397 V468 G474 G476 S482I397-A478 HydrophobicContact CD1-CB 4.03Å; V468-A478 HydrophobicContact CG1-CB 3.7Å; G474-A478 WeakPolarHBondContact O-CB 3.28Å; G474-A478 PolarHBondContact O-N 3.41Å; G476-A478 VanDerWaalsContact C-N 3.32Å; G476-A478 PolarHBondContact O-N 2.94Å; A478-S482 WeakPolarHBondContact O-CB 3.45Å; A478-S482 PolarHBondContact O-N 3.48Å; A478-S482 VanDerWaalsContact O-N 3.09Å; A478-S482 PolarHBondContact O-OG 2.83Å
479A97.6Very high95.7Very high0 Ų014.4 Ų14.40%07%0.072CC..Hα-helixtrans-62.9-44.4175.100000111.2A475 G476 S482 F483 L503 V516 P602A475-A479 WeakPolarHBondContact O-CB 3.46Å; A475-A479 PolarHBondContact O-N 3.08Å; G476-A479 PolarHBondContact O-N 3.01Å; A479-S482 WeakPolarHBondContact O-CB 3.46Å; A479-S482 PolarHBondContact O-N 3.39Å; A479-F483 VanDerWaalsContact O-CD2 3.29Å; A479-F483 WeakPolarHBondContact O-CD2 3.42Å; A479-F483 PolarHBondContact O-N 2.95Å; A479-L503 HydrophobicContact CB-CD2 3.95Å; A479-V516 HydrophobicContact CB-CG1 4.41Å; A479-V516 HydrophobicContact CB-CG2 4.42Å; A479-P602 HydrophobicContact CB-CB 3.95Å; A479-P602 HydrophobicContact CB-CG 3.86Å
480I97.1Very high95.4Very high0 Ų018.7 Ų18.70%010%0.1CC..Hα-helixtrans-68.7-48.1178.8-66.1169.8000111.9L417 M432 V433 A436 G476 T477 S482 F483 L484 L503 L504L417-I480 HydrophobicContact CD2-CB 4.38Å; L417-I480 HydrophobicContact CD2-CG1 4.2Å; L417-I480 HydrophobicContact CD2-CG2 3.48Å; L417-I480 VanDerWaalsContact CD2-CG2 3.48Å; M432-I480 HydrophobicContact CB-CD1 3.77Å; V433-I480 HydrophobicContact CG2-CD1 3.98Å; V433-I480 HydrophobicContact CG2-CG2 4.45Å; A436-I480 HydrophobicContact CB-CB 4.03Å; A436-I480 HydrophobicContact CB-CG2 3.61Å; G476-I480 PolarHBondContact O-N 3.23Å; T477-I480 PolarHBondContact O-N 3.38Å; I480-S482 PolarHBondContact O-N 3.44Å; I480-S482 VanDerWaalsContact O-N 3.11Å; I480-F483 WeakPolarHBondContact O-CB 3.45Å; I480-F483 PolarHBondContact O-N 2.97Å; I480-L484 PolarHBondContact O-N 3.07Å; I480-L503 HydrophobicContact CD1-CD1 3.87Å; I480-L503 HydrophobicContact CD1-CG 4.41Å; I480-L503 HydrophobicContact CG1-CD1 4.46Å; I480-L504 HydrophobicContact CG1-CD2 4.12Å
481L97.5Very high95.2Very high0 Ų024.3 Ų24.30%013%0.134CC..Hα-helixtrans-54.4-33.7175.6178.963.9000111.7I395 I397 A436 I439 K440 L443 V468 T477 F483 L484 L485I395-L481 HydrophobicContact CD1-CD2 4.49Å; I395-L481 HydrophobicContact CG2-CD2 4.21Å; I397-L481 HydrophobicContact CD1-CD2 3.93Å; A436-L481 HydrophobicContact CB-CB 4.04Å; I439-L481 HydrophobicContact CB-CD2 4.34Å; I439-L481 HydrophobicContact CG2-CD1 4.46Å; I439-L481 HydrophobicContact CG2-CD2 3.63Å; K440-L481 HydrophobicContact CB-CD1 3.87Å; L443-L481 HydrophobicContact CD1-CD2 4.42Å; V468-L481 HydrophobicContact CG1-CD2 4.1Å; T477-L481 VanDerWaalsContact O-CB 3.23Å; T477-L481 WeakPolarHBondContact O-CB 3.24Å; T477-L481 PolarHBondContact O-N 2.89Å; L481-F483 PolarHBondContact O-N 3.38Å; L481-L484 PolarHBondContact O-N 2.96Å; L481-L484 VanDerWaalsContact O-N 3.12Å; L481-L485 HydrophobicContact CD1-CD1 3.95Å; L481-L485 HydrophobicContact CD1-CG 4Å; L481-L485 HydrophobicContact CD2-CD1 4.27Å; L481-L485 HydrophobicContact CG-CD1 3.82Å; L481-L485 HydrophobicContact CG-CG 4.22Å; L481-L485 WeakPolarHBondContact O-CG 3.49Å; L481-L485 PolarHBondContact O-N 3.47Å
482S97.2Very high95.2Very high0 Ų024.5 Ų24.50%014%0.135CC..Hα-helixtrans-64.2-34.3175.4-61.40000113.3V468 A478 A479 I480 R486 C494V468-S482 WeakPolarHBondContact CB-OG 3.5Å; V468-S482 WeakPolarHBondContact CG2-OG 3.41Å; A478-S482 WeakPolarHBondContact O-CB 3.45Å; A478-S482 PolarHBondContact O-N 3.48Å; A478-S482 VanDerWaalsContact O-N 3.09Å; A478-S482 PolarHBondContact O-OG 2.83Å; A479-S482 WeakPolarHBondContact O-CB 3.46Å; A479-S482 PolarHBondContact O-N 3.39Å; I480-S482 PolarHBondContact O-N 3.44Å; I480-S482 VanDerWaalsContact O-N 3.11Å; S482-R486 VanDerWaalsContact O-CB 3.25Å; S482-R486 WeakPolarHBondContact O-CB 3.22Å; S482-R486 PolarHBondContact O-N 2.9Å; S482-R486 VanDerWaalsContact O-N 3.07Å; S482-C494 VanDerWaalsContact OG-CB 3.32Å; S482-C494 WeakPolarHBondContact OG-CB 3.36Å
483F95.3Very high95.3Very high3 Ų328 Ų281%0.01315%0.149CC..Hα-helixtrans-62.3-44.5169.2-75.7-107.5000111V419 W426 A479 I480 L481 L485 P487 L504 A508 Y511 F515V419-F483 HydrophobicContact CG2-CB 3.93Å; V419-F483 HydrophobicContact CG2-CD1 4.49Å; W426-F483 HydrophobicContact CD2-CE1 4.48Å; W426-F483 AromaticContact CE3-CD1 3.88Å; W426-F483 HydrophobicContact CE3-CD1 3.88Å; W426-F483 AromaticContact CE3-CE1 3.79Å; W426-F483 HydrophobicContact CE3-CE1 3.79Å; W426-F483 HydrophobicContact CH2-CE1 4.41Å; W426-F483 AromaticContact CZ3-CD1 3.73Å; W426-F483 HydrophobicContact CZ3-CD1 3.73Å; W426-F483 AromaticContact CZ3-CE1 3.76Å; W426-F483 HydrophobicContact CZ3-CE1 3.76Å; A479-F483 VanDerWaalsContact O-CD2 3.29Å; A479-F483 WeakPolarHBondContact O-CD2 3.42Å; A479-F483 PolarHBondContact O-N 2.95Å; I480-F483 WeakPolarHBondContact O-CB 3.45Å; I480-F483 PolarHBondContact O-N 2.97Å; L481-F483 PolarHBondContact O-N 3.38Å; F483-L485 VanDerWaalsContact C-N 3.33Å; F483-L485 PolarHBondContact O-N 3.46Å; F483-P487 VanDerWaalsContact O-CD 3.24Å; F483-P487 WeakPolarHBondContact O-CD 3.47Å; F483-L504 HydrophobicContact CE2-CD1 3.84Å; F483-L504 HydrophobicContact CE2-CD2 4.26Å; F483-L504 HydrophobicContact CZ-CD1 3.93Å; F483-A508 HydrophobicContact CE1-CB 4.15Å; F483-A508 HydrophobicContact CZ-CB 4.03Å; F483-A508 WeakPolarHBondContact CZ-O 3.48Å; F483-Y511 HydrophobicContact CD1-CD1 4.05Å; F483-Y511 HydrophobicContact CD1-CE1 4.18Å; F483-Y511 AromaticContact CE1-CD1 3.6Å; F483-Y511 HydrophobicContact CE1-CD1 3.6Å; F483-Y511 HydrophobicContact CE1-CE1 4.2Å; F483-Y511 HydrophobicContact CZ-CD1 4.34Å; F483-F515 HydrophobicContact CD1-CZ 4.34Å; F483-F515 HydrophobicContact CD2-CE2 4.23Å; F483-F515 AromaticContact CD2-CZ 3.86Å; F483-F515 HydrophobicContact CD2-CZ 3.86Å; F483-F515 HydrophobicContact CE1-CZ 4.39Å; F483-F515 HydrophobicContact CE2-CE2 4.44Å; F483-F515 AromaticContact CE2-CZ 3.89Å; F483-F515 HydrophobicContact CE2-CZ 3.89Å; F483-F515 HydrophobicContact CG-CZ 4.08Å; F483-F515 HydrophobicContact CZ-CZ 4.17Å
484L94.9Very high95.6Very high12 Ų1228 Ų286%0.06315%0.149CC..Hα-helixtrans-71.1-29.6-173.1-45-172.2000112.5P418 V419 A436 E437 K440 I480 L481P418-L484 HydrophobicContact CG-CD1 4.23Å; P418-L484 HydrophobicContact CG-CD2 3.77Å; V419-L484 HydrophobicContact CG2-CD2 3.91Å; A436-L484 HydrophobicContact CB-CD1 4.14Å; E437-L484 HydrophobicContact CG-CD1 4.36Å; K440-L484 HydrophobicContact CD-CB 3.85Å; K440-L484 HydrophobicContact CD-CD1 4.24Å; I480-L484 PolarHBondContact O-N 3.07Å; L481-L484 PolarHBondContact O-N 2.96Å; L481-L484 VanDerWaalsContact O-N 3.12Å
485L95.4Very high95.7Very high1 Ų128 Ų281%0.00515%0.15CC..Hα-helixtrans-90.6-23.1178.6-64.8179.9000113.7I395 L443 L466 L481 F483 P487 Q488 Y489 L492I395-L485 HydrophobicContact CD1-CD1 3.7Å; L443-L485 HydrophobicContact CD1-CD1 4.43Å; L466-L485 HydrophobicContact CD2-CD1 4.32Å; L481-L485 HydrophobicContact CD1-CD1 3.95Å; L481-L485 HydrophobicContact CD1-CG 4Å; L481-L485 HydrophobicContact CD2-CD1 4.27Å; L481-L485 HydrophobicContact CG-CD1 3.82Å; L481-L485 HydrophobicContact CG-CG 4.22Å; L481-L485 WeakPolarHBondContact O-CG 3.49Å; L481-L485 PolarHBondContact O-N 3.47Å; F483-L485 VanDerWaalsContact C-N 3.33Å; F483-L485 PolarHBondContact O-N 3.46Å; L485-P487 VanDerWaalsContact C-CD 3.46Å; L485-Q488 PolarHBondContact O-N 3.37Å; L485-Y489 HydrophobicContact CB-CD2 4.35Å; L485-Y489 PolarHBondContact O-N 3.11Å; L485-L492 HydrophobicContact CB-CD1 3.79Å
486R92.3Very high95.7Very high38 Ų3828 Ų2814%0.14315%0.15CC..THydrogen-bonded Turntrans-58.3-33.7-176.4-166.7172.5-171.4-147.30.2115.3S482 Q488 Y489 P490 Y511 E514 F515S482-R486 VanDerWaalsContact O-CB 3.25Å; S482-R486 WeakPolarHBondContact O-CB 3.22Å; S482-R486 PolarHBondContact O-N 2.9Å; S482-R486 VanDerWaalsContact O-N 3.07Å; R486-Q488 VanDerWaalsContact C-N 3.26Å; R486-Q488 PolarHBondContact O-N 2.76Å; R486-Y489 CarbonylContact O-C 3.59Å; R486-Y489 PolarHBondContact O-N 3.27Å; R486-P490 WeakPolarHBondContact O-CA 3.45Å; R486-Y511 PolarHBondContact NH1-OH 3.37Å; R486-E514 IonicContact CZ-OE2 3.23Å; R486-E514 IonicContact NH1-OE2 3.25Å; R486-E514 PolarHBondContact NH1-OE2 2.99Å; R486-E514 IonicContact NH2-OE2 3.25Å; R486-E514 PolarHBondContact NH2-OE2 2.71Å; R486-F515 VanDerWaalsContact NH1-CD1 3.33Å
487P90.9Very high95.8Very high83 Ų8328.1 Ų28.154%0.53915%0.15SC..THydrogen-bonded Turntrans-59.4-34.4172.6-2735.8000113.7F483 L485F483-P487 VanDerWaalsContact O-CD 3.24Å; F483-P487 WeakPolarHBondContact O-CD 3.47Å; L485-P487 VanDerWaalsContact C-CD 3.46Å
488Q90.8Very high95.8Very high101 Ų10128.1 Ų28.147%0.47215%0.15SC..THydrogen-bonded Turntrans-86.1-31.5176-60178.314.700112E444 L485 R486E444-Q488 PolarHBondContact OE1-NE2 2.97Å; L485-Q488 PolarHBondContact O-N 3.37Å; R486-Q488 VanDerWaalsContact C-N 3.26Å; R486-Q488 PolarHBondContact O-N 2.76Å
489Y93.6Very high95.7Very high58 Ų5828.1 Ų28.123%0.22715%0.15CC..  trans-128.175.5-176-58.2-85.4000112L449 F453 L466 L485 R486 T491 L492L449-Y489 HydrophobicContact CD1-CE2 3.95Å; F453-Y489 HydrophobicContact CD2-CE1 4.43Å; F453-Y489 HydrophobicContact CE2-CD1 4.38Å; F453-Y489 AromaticContact CE2-CE1 3.47Å; F453-Y489 HydrophobicContact CE2-CE1 3.47Å; F453-Y489 VanDerWaalsContact CE2-CE1 3.47Å; F453-Y489 AromaticContact CE2-CZ 3.92Å; F453-Y489 HydrophobicContact CZ-CD1 4.31Å; F453-Y489 AromaticContact CZ-CE1 3.81Å; F453-Y489 HydrophobicContact CZ-CE1 3.81Å; L466-Y489 HydrophobicContact CB-CD1 4.44Å; L466-Y489 HydrophobicContact CD2-CD1 3.98Å; L466-Y489 HydrophobicContact CD2-CD2 3.68Å; L466-Y489 HydrophobicContact CD2-CE1 4.35Å; L466-Y489 HydrophobicContact CD2-CE2 4.1Å; L466-Y489 HydrophobicContact CD2-CG 3.63Å; L485-Y489 HydrophobicContact CB-CD2 4.35Å; L485-Y489 PolarHBondContact O-N 3.11Å; R486-Y489 CarbonylContact O-C 3.59Å; R486-Y489 PolarHBondContact O-N 3.27Å; Y489-T491 PolarHBondContact O-N 3.17Å; Y489-L492 WeakPolarHBondContact O-CB 3.38Å; Y489-L492 PolarHBondContact O-N 3.41Å
490P92.1Very high95.5Very high90 Ų9028.7 Ų28.758%0.58415%0.154SC*.THydrogen-bonded Turntrans-62.6-21.1-172.1-26.736.4000115.7R486R486-P490 WeakPolarHBondContact O-CA 3.45Å
491T94.3Very high95Very high118 Ų11828.8 Ų28.872%0.72415%0.154SC*.THydrogen-bonded Turntrans-937.9179.456.10000114.1Y489Y489-T491 PolarHBondContact O-N 3.17Å
492L96.5Very high94.6Very high5 Ų529 Ų293%0.02616%0.157CC..  trans-57.7140.6175.2178.9157.6000111.4L466 V468 L485 Y489 F515L466-L492 HydrophobicContact CD2-CD1 4.01Å; L466-L492 HydrophobicContact CG-CD1 4.16Å; L466-L492 WeakPolarHBondContact O-CA 3.48Å; V468-L492 HydrophobicContact CG2-CD1 3.83Å; V468-L492 HydrophobicContact CG2-CD2 4.18Å; V468-L492 HydrophobicContact CG2-CG 4.16Å; L485-L492 HydrophobicContact CB-CD1 3.79Å; Y489-L492 WeakPolarHBondContact O-CB 3.38Å; Y489-L492 PolarHBondContact O-N 3.41Å; L492-F515 HydrophobicContact CD2-CD2 4.26Å
493K97.8Very high94.4Very high78 Ų7829 Ų2934%0.33916%0.157SC..EExtended strand (participates in β ladder)trans-118.4153.6163.9-62.7178.1178.1174.30110.3E291 L466 I467 V468 F495 F515E291-K493 IonicContact OE1-NZ 3.4Å; E291-K493 PolarHBondContact OE1-NZ 2.83Å; E291-K493 IonicContact OE2-NZ 3.24Å; E291-K493 PolarHBondContact OE2-NZ 3.45Å; L466-K493 PolarHBondContact O-N 2.95Å; I467-K493 WeakPolarHBondContact CA-O 3.45Å; I467-K493 HydrophobicContact CD1-CB 3.95Å; I467-K493 HydrophobicContact CD1-CD 4.44Å; V468-K493 PolarHBondContact N-O 3.44Å; K493-F495 HydrophobicContact CB-CE2 4.45Å; K493-F495 HydrophobicContact CD-CE2 4.45Å; K493-F495 HydrophobicContact CD-CZ 4.34Å; K493-F515 WeakPolarHBondContact CA-O 3.36Å
494C98.5Very high94.3Very high0 Ų028.9 Ų28.90%016%0.156CC..EExtended strand (participates in β ladder)trans-120.9139171-173.30000111.3V468 S482 F515 V516 T517V468-C494 VanDerWaalsContact O-CA 3.28Å; V468-C494 WeakPolarHBondContact O-CA 3.46Å; S482-C494 VanDerWaalsContact OG-CB 3.32Å; S482-C494 WeakPolarHBondContact OG-CB 3.36Å; C494-F515 PolarHBondContact N-O 3.01Å; C494-V516 HydrophobicContact CB-CB 4.28Å; C494-V516 HydrophobicContact CB-CG1 4.17Å; C494-V516 HydrophobicContact CB-CG2 3.96Å; C494-T517 PolarHBondContact O-N 2.8Å
495F98.6Very high94.2Very high2 Ų228.7 Ų28.71%0.00916%0.156CC..EExtended strand (participates in β ladder)trans-116.4112.3169.7-65.5-81.8000109.6E291 V292 Y295 I467 V468 V469 G470 K493 Y497 T517E291-F495 HydrophobicContact CB-CE1 4.37Å; E291-F495 HydrophobicContact CB-CZ 4Å; V292-F495 HydrophobicContact CG2-CD1 3.92Å; V292-F495 HydrophobicContact CG2-CE1 3.75Å; Y295-F495 AromaticContact CD2-CD2 3.52Å; Y295-F495 HydrophobicContact CD2-CD2 3.52Å; Y295-F495 HydrophobicContact CD2-CE1 4.41Å; Y295-F495 AromaticContact CD2-CE2 3.2Å; Y295-F495 HydrophobicContact CD2-CE2 3.2Å; Y295-F495 HydrophobicContact CD2-CG 4.27Å; Y295-F495 AromaticContact CD2-CZ 3.7Å; Y295-F495 HydrophobicContact CD2-CZ 3.7Å; Y295-F495 HydrophobicContact CE2-CD2 4.25Å; Y295-F495 AromaticContact CE2-CE2 3.53Å; Y295-F495 HydrophobicContact CE2-CE2 3.53Å; Y295-F495 HydrophobicContact CE2-CZ 4.01Å; Y295-F495 AromaticContact CG-CD2 3.85Å; Y295-F495 HydrophobicContact CG-CD2 3.85Å; Y295-F495 AromaticContact CG-CE2 3.98Å; Y295-F495 HydrophobicContact CG-CE2 3.98Å; I467-F495 HydrophobicContact CD1-CE2 4.39Å; I467-F495 HydrophobicContact CG2-CD2 3.89Å; I467-F495 HydrophobicContact CG2-CE2 4.23Å; V468-F495 PolarHBondContact O-N 3.22Å; V469-F495 WeakPolarHBondContact CA-O 3.39Å; V469-F495 HydrophobicContact CG2-CB 4.09Å; G470-F495 PolarHBondContact N-O 2.86Å; K493-F495 HydrophobicContact CB-CE2 4.45Å; K493-F495 HydrophobicContact CD-CE2 4.45Å; K493-F495 HydrophobicContact CD-CZ 4.34Å; F495-Y497 HydrophobicContact CB-CE2 3.8Å; F495-Y497 WeakPolarHBondContact CB-OH 3.4Å; F495-T517 WeakPolarHBondContact CA-O 3.45Å
496A98.2Very high94Very high0 Ų032.6 Ų32.60%017%0.174CC..EExtended strand (participates in β ladder)trans-112.9107.6-172.100000110.2A475 P499 V516 T517 A518 V519A475-A496 HydrophobicContact CB-CB 4.01Å; A496-P499 HydrophobicContact CB-CB 4.32Å; A496-P499 HydrophobicContact CB-CG 4.22Å; A496-V516 HydrophobicContact CB-CG1 3.99Å; A496-T517 PolarHBondContact N-O 2.86Å; A496-A518 HydrophobicContact CB-CB 4.4Å; A496-A518 CarbonylContact O-C 3.53Å; A496-A518 VanDerWaalsContact O-CA 3.23Å; A496-A518 WeakPolarHBondContact O-CA 3.46Å; A496-V519 PolarHBondContact O-N 3.39Å
497Y98.4Very high94Very high1 Ų135.5 Ų35.50%0.00419%0.193CC..EExtended strand (participates in β ladder)trans-97.2121.2-177.8-56.7-84.9000110.6V292 M296 A299 V469 G470 H471 S472 A475 F495 V519 V655 L659V292-Y497 HydrophobicContact CG1-CE1 3.92Å; V292-Y497 PolarHBondContact O-OH 3.34Å; M296-Y497 HydrophobicContact CB-CD1 4.24Å; M296-Y497 HydrophobicContact CB-CE1 3.74Å; M296-Y497 HydrophobicContact CB-CE2 4.17Å; M296-Y497 HydrophobicContact CE-CG 4.47Å; M296-Y497 HydrophobicContact CG-CD1 4.2Å; M296-Y497 HydrophobicContact CG-CE1 4.21Å; M296-Y497 HydrophobicContact CG-CG 4.49Å; M296-Y497 PolarHBondContact N-OH 3.5Å; M296-Y497 HydrophobicContact SD-CD1 3.47Å; M296-Y497 WeakPolarHBondContact SD-CD1 3.3Å; M296-Y497 HydrophobicContact SD-CD2 3.47Å; M296-Y497 WeakPolarHBondContact SD-CD2 3.1Å; M296-Y497 HydrophobicContact SD-CE1 3.96Å; M296-Y497 HydrophobicContact SD-CE2 3.95Å; M296-Y497 HydrophobicContact SD-CG 3.24Å; A299-Y497 HydrophobicContact CB-CD2 3.94Å; A299-Y497 HydrophobicContact CB-CE2 4.27Å; V469-Y497 HydrophobicContact CG2-CD2 4.24Å; V469-Y497 HydrophobicContact CG2-CE2 3.64Å; G470-Y497 WeakPolarHBondContact O-CD2 3.47Å; G470-Y497 PolarHBondContact O-N 3.49Å; H471-Y497 CarbonylContact C-O 3.5Å; H471-Y497 VanDerWaalsContact CA-O 3.3Å; H471-Y497 WeakPolarHBondContact CA-O 3.46Å; H471-Y497 PolarHBondContact CD2-O 3.15Å; S472-Y497 PolarHBondContact N-O 3.07Å; A475-Y497 VanDerWaalsContact CB-O 3.31Å; A475-Y497 WeakPolarHBondContact CB-O 3.39Å; F495-Y497 HydrophobicContact CB-CE2 3.8Å; F495-Y497 WeakPolarHBondContact CB-OH 3.4Å; Y497-V519 HydrophobicContact CD1-CB 3.75Å; Y497-V519 HydrophobicContact CD1-CG1 4.31Å; Y497-V519 HydrophobicContact CD1-CG2 3.72Å; Y497-V519 HydrophobicContact CE1-CB 4.27Å; Y497-V519 HydrophobicContact CE1-CG2 3.71Å; Y497-V655 HydrophobicContact CD1-CG1 4.48Å; Y497-L659 HydrophobicContact CD1-CD1 4.45Å; Y497-L659 HydrophobicContact CE1-CD1 4.18Å
498S96.9Very high94.1Very high0 Ų031.6 Ų31.60%017%0.167CC..SBendtrans4851.3-174.3-65.70000114.4S472 V519 D524S472-S498 WeakPolarHBondContact CA-O 3.27Å; S498-V519 WeakPolarHBondContact CA-O 3.41Å; S498-V519 PolarHBondContact N-O 3.01Å; S498-D524 WeakPolarHBondContact CB-OD2 3.33Å; S498-D524 PolarHBondContact OG-OD2 2.99Å
499P96.1Very high94.3Very high0 Ų026.8 Ų26.80%015%0.145CC..  trans-64.9150.4176.630.7-35.6000110.9A475 A496 A518 P527 P602A475-P499 HydrophobicContact CB-CB 3.94Å; A496-P499 HydrophobicContact CB-CB 4.32Å; A496-P499 HydrophobicContact CB-CG 4.22Å; P499-A518 HydrophobicContact CG-CB 4.08Å; P499-P527 VanDerWaalsContact O-CA 3.25Å; P499-P527 WeakPolarHBondContact O-CA 3.3Å; P499-P527 WeakPolarHBondContact O-CG 3.25Å; P499-P602 HydrophobicContact CB-CG 3.86Å; P499-P602 HydrophobicContact CG-CG 3.95Å
500P92.7Very high94.3Very high13 Ų1329 Ų298%0.08416%0.157CC..  trans-64.6150-17829-37000112.3M432 L503 V526M432-P500 HydrophobicContact CE-CG 3.8Å; M432-P500 HydrophobicContact SD-CG 3.77Å; P500-L503 HydrophobicContact CG-CB 4.25Å; P500-L503 HydrophobicContact CG-CD1 3.95Å; P500-V526 WeakPolarHBondContact CA-O 3.49Å; P500-V526 HydrophobicContact CB-CG1 4.07Å
501G88.1Confident94.4Very high1 Ų128.1 Ų28.11%0.0114%0.143CC..THydrogen-bonded Turntrans-65.5-42178.900000112.3L503 V526 P527 I529 L599 Y600 P601G501-L503 VanDerWaalsContact C-N 3.27Å; G501-L503 PolarHBondContact O-N 3.28Å; G501-L503 VanDerWaalsContact O-N 3.08Å; G501-V526 PolarHBondContact N-O 2.96Å; G501-P527 WeakPolarHBondContact CA-O 3.35Å; G501-P527 PolarHBondContact N-O 3.43Å; G501-I529 CarbonylContact C-O 3.51Å; G501-I529 WeakPolarHBondContact CA-O 3.29Å; G501-I529 PolarHBondContact N-O 2.76Å; G501-I529 VanDerWaalsContact N-O 3.16Å; G501-L599 CarbonylContact O-C 3.59Å; G501-Y600 CarbonylContact O-C 3.58Å; G501-Y600 WeakPolarHBondContact O-CA 3.47Å; G501-Y600 PolarHBondContact O-N 3.13Å; G501-P601 WeakPolarHBondContact O-CD 3.36Å; G501-P601 VanDerWaalsContact O-N 3.09Å
502G87.6Confident94.5Very high5 Ų522.5 Ų22.55%0.05211%0.108CC..THydrogen-bonded Turntrans-8141179.600000115.6I529 L599G502-I529 PolarHBondContact N-O 3.15Å; G502-L599 VanDerWaalsContact C-CB 3.41Å; G502-L599 VanDerWaalsContact O-CD1 3.24Å; G502-L599 WeakPolarHBondContact O-CD1 3.49Å
503L92.7Very high94.5Very high0 Ų024 Ų240%012%0.115CC..  trans-86.6-55.9-171.6-167.471.1000115.9G428 H429 M432 A479 I480 P500 G501 P602G428-L503 CarbonylContact C-O 3.55Å; G428-L503 WeakPolarHBondContact CA-O 3.32Å; H429-L503 HydrophobicContact CB-CD1 4.1Å; H429-L503 PolarHBondContact N-O 3.08Å; M432-L503 HydrophobicContact CB-CD1 4.34Å; M432-L503 HydrophobicContact SD-CD1 3.63Å; A479-L503 HydrophobicContact CB-CD2 3.95Å; I480-L503 HydrophobicContact CD1-CD1 3.87Å; I480-L503 HydrophobicContact CD1-CG 4.41Å; I480-L503 HydrophobicContact CG1-CD1 4.46Å; P500-L503 HydrophobicContact CG-CB 4.25Å; P500-L503 HydrophobicContact CG-CD1 3.95Å; G501-L503 VanDerWaalsContact C-N 3.27Å; G501-L503 PolarHBondContact O-N 3.28Å; G501-L503 VanDerWaalsContact O-N 3.08Å; L503-P602 HydrophobicContact CD2-CB 3.99Å; L503-P602 HydrophobicContact CD2-CG 3.57Å
504L94Very high94.4Very high0 Ų026.1 Ų26.10%013%0.126CC..BIsolated β-bridgetrans-128.4148.1-166.7-63.4-180000113.2L417 L427 I480 F483 A508 M509 L599 Y600 P602L417-L504 HydrophobicContact CD1-CD2 4.02Å; L427-L504 WeakPolarHBondContact O-CA 3.23Å; I480-L504 HydrophobicContact CG1-CD2 4.12Å; F483-L504 HydrophobicContact CE2-CD1 3.84Å; F483-L504 HydrophobicContact CE2-CD2 4.26Å; F483-L504 HydrophobicContact CZ-CD1 3.93Å; L504-A508 HydrophobicContact CB-CB 4.21Å; L504-M509 HydrophobicContact CB-CB 4.23Å; L504-L599 CarbonylContact O-C 3.56Å; L504-L599 VanDerWaalsContact O-CA 3.25Å; L504-L599 WeakPolarHBondContact O-CA 3.47Å; L504-Y600 PolarHBondContact N-O 3.02Å; L504-Y600 PolarHBondContact O-N 2.77Å; L504-P602 HydrophobicContact CD1-CB 3.76Å
505S92.6Very high94.3Very high8 Ų826.5 Ų26.56%0.05613%0.128CC..  trans-64.3159.2166.964.20000111.7L427 D507 A508 M509L427-S505 PolarHBondContact N-OG 2.98Å; L427-S505 VanDerWaalsContact N-OG 3.08Å; L427-S505 PolarHBondContact O-N 3.4Å; S505-D507 PolarHBondContact O-N 2.9Å; S505-A508 PolarHBondContact O-N 2.99Å; S505-A508 VanDerWaalsContact O-N 3.11Å; S505-M509 WeakPolarHBondContact O-CB 3.26Å; S505-M509 PolarHBondContact O-N 3.26Å
506E91.4Very high94.3Very high84 Ų8426.5 Ų26.539%0.39313%0.127SC..Hα-helixtrans-55.7-45.8-171.2-169.5165.1148.200113.5A508 M509 E510 Y600 K635E506-A508 VanDerWaalsContact C-N 3.35Å; E506-A508 PolarHBondContact O-N 3.31Å; E506-M509 HydrophobicContact CG-CE 4.05Å; E506-M509 WeakPolarHBondContact O-CB 3.4Å; E506-M509 PolarHBondContact O-N 3.45Å; E506-E510 PolarHBondContact O-N 2.87Å; E506-Y600 HydrophobicContact CB-CD2 4.26Å; E506-Y600 HydrophobicContact CB-CE2 3.97Å; E506-Y600 HydrophobicContact CG-CE2 4.38Å; E506-K635 WeakPolarHBondContact OE1-CE 3.47Å; E506-K635 IonicContact OE1-NZ 3.43Å; E506-K635 PolarHBondContact OE1-NZ 2.93Å; E506-K635 WeakPolarHBondContact OE2-CE 3.49Å; E506-K635 IonicContact OE2-NZ 3.19Å; E506-K635 PolarHBondContact OE2-NZ 2.85Å
507D91.8Very high94.3Very high99 Ų9927.5 Ų27.553%0.52913%0.134SC..Hα-helixtrans-62.3-40.8178.3-57.7-31.4000112.5S505 E510 Y511S505-D507 PolarHBondContact O-N 2.9Å; D507-E510 PolarHBondContact O-N 2.68Å; D507-Y511 PolarHBondContact O-N 3.08Å
508A93.5Very high94.3Very high0 Ų027.4 Ų27.40%013%0.133CC..Hα-helixtrans-70.2-40.8178.100000110.8L417 W426 F483 L504 S505 E506 E510 Y511 S512L417-A508 HydrophobicContact CD1-CB 4.11Å; W426-A508 HydrophobicContact CB-CB 4.1Å; W426-A508 HydrophobicContact CD2-CB 4.19Å; W426-A508 HydrophobicContact CG-CB 3.88Å; F483-A508 HydrophobicContact CE1-CB 4.15Å; F483-A508 HydrophobicContact CZ-CB 4.03Å; F483-A508 WeakPolarHBondContact CZ-O 3.48Å; L504-A508 HydrophobicContact CB-CB 4.21Å; S505-A508 PolarHBondContact O-N 2.99Å; S505-A508 VanDerWaalsContact O-N 3.11Å; E506-A508 VanDerWaalsContact C-N 3.35Å; E506-A508 PolarHBondContact O-N 3.31Å; A508-E510 VanDerWaalsContact C-N 3.34Å; A508-E510 PolarHBondContact O-N 2.88Å; A508-Y511 PolarHBondContact O-N 3.4Å; A508-S512 WeakPolarHBondContact O-CB 3.33Å; A508-S512 PolarHBondContact O-N 3.4Å
509M94.8Very high94.3Very high1 Ų127.5 Ų27.51%0.00513%0.134CC..Hα-helixtrans-57.8-45.5172.9176-77.4-57.700110.9L504 S505 E506 S512 K513 P601 N634L504-M509 HydrophobicContact CB-CB 4.23Å; S505-M509 WeakPolarHBondContact O-CB 3.26Å; S505-M509 PolarHBondContact O-N 3.26Å; E506-M509 HydrophobicContact CG-CE 4.05Å; E506-M509 WeakPolarHBondContact O-CB 3.4Å; E506-M509 PolarHBondContact O-N 3.45Å; M509-S512 PolarHBondContact O-N 3.04Å; M509-S512 PolarHBondContact O-OG 3.37Å; M509-K513 HydrophobicContact SD-CD 4.45Å; M509-K513 WeakPolarHBondContact SD-CE 3.2Å; M509-P601 VanDerWaalsContact CG-O 3.32Å; M509-P601 WeakPolarHBondContact CG-O 3.35Å; M509-N634 HydrophobicContact CE-CB 4.32Å; M509-N634 HydrophobicContact CG-CB 3.96Å; M509-N634 HydrophobicContact SD-CB 3.56Å; M509-N634 VanDerWaalsContact SD-CB 3.56Å
510E94.6Very high94.3Very high105 Ų10527.5 Ų27.549%0.49113%0.134SC..Hα-helixtrans-64.9-47.8178.8-159.963.3-136.800111.7E506 D507 A508 S512 K513E506-E510 PolarHBondContact O-N 2.87Å; D507-E510 PolarHBondContact O-N 2.68Å; A508-E510 VanDerWaalsContact C-N 3.34Å; A508-E510 PolarHBondContact O-N 2.88Å; E510-S512 VanDerWaalsContact C-N 3.26Å; E510-S512 PolarHBondContact O-N 3.24Å; E510-K513 VanDerWaalsContact O-CB 3.31Å; E510-K513 WeakPolarHBondContact O-CB 3.49Å; E510-K513 PolarHBondContact O-N 3.02Å; E510-K513 VanDerWaalsContact O-N 3.12Å; E510-K513 WeakPolarHBondContact OE1-CD 3.26Å; E510-K513 IonicContact OE1-NZ 2.71Å; E510-K513 PolarHBondContact OE1-NZ 2.83Å; E510-K513 IonicContact OE2-NZ 2.64Å; E510-K513 PolarHBondContact OE2-NZ 3.15Å
511Y94.1Very high94.4Very high70 Ų7027.1 Ų27.128%0.27513%0.131SC..Hα-helixtrans-58.4-37175.7179.9-103000112.7W426 F483 R486 D507 A508 K513 E514 F515W426-Y511 AromaticContact CH2-CD1 3.33Å; W426-Y511 HydrophobicContact CH2-CD1 3.33Å; W426-Y511 AromaticContact CH2-CD2 3.84Å; W426-Y511 HydrophobicContact CH2-CD2 3.84Å; W426-Y511 AromaticContact CH2-CE1 3.63Å; W426-Y511 HydrophobicContact CH2-CE1 3.63Å; W426-Y511 HydrophobicContact CH2-CE2 4.11Å; W426-Y511 AromaticContact CH2-CG 3.43Å; W426-Y511 HydrophobicContact CH2-CG 3.43Å; W426-Y511 VanDerWaalsContact CH2-CG 3.43Å; W426-Y511 AromaticContact CH2-CZ 3.99Å; W426-Y511 HydrophobicContact CZ2-CD1 4.07Å; W426-Y511 HydrophobicContact CZ2-CD2 4.21Å; W426-Y511 AromaticContact CZ2-CG 3.78Å; W426-Y511 HydrophobicContact CZ2-CG 3.78Å; W426-Y511 AromaticContact CZ3-CD1 3.79Å; W426-Y511 HydrophobicContact CZ3-CD1 3.79Å; W426-Y511 AromaticContact CZ3-CE1 3.92Å; W426-Y511 HydrophobicContact CZ3-CE1 3.92Å; W426-Y511 HydrophobicContact CZ3-CG 4.33Å; F483-Y511 HydrophobicContact CD1-CD1 4.05Å; F483-Y511 HydrophobicContact CD1-CE1 4.18Å; F483-Y511 AromaticContact CE1-CD1 3.6Å; F483-Y511 HydrophobicContact CE1-CD1 3.6Å; F483-Y511 HydrophobicContact CE1-CE1 4.2Å; F483-Y511 HydrophobicContact CZ-CD1 4.34Å; R486-Y511 PolarHBondContact NH1-OH 3.37Å; D507-Y511 PolarHBondContact O-N 3.08Å; A508-Y511 PolarHBondContact O-N 3.4Å; Y511-K513 PolarHBondContact O-N 3.38Å; Y511-K513 VanDerWaalsContact O-N 3.15Å; Y511-E514 PolarHBondContact O-N 3.29Å; Y511-F515 AromaticContact CD1-CE1 3.71Å; Y511-F515 HydrophobicContact CD1-CE1 3.71Å; Y511-F515 HydrophobicContact CD1-CZ 4.28Å; Y511-F515 AromaticContact CE1-CE1 3.63Å; Y511-F515 HydrophobicContact CE1-CE1 3.63Å; Y511-F515 HydrophobicContact CE1-CZ 4.22Å
512S96.1Very high94.6Very high0 Ų027 Ų270%013%0.13CC..Hα-helixtrans-63-20.6179.476.50000113.8A508 M509 E510 E514 F515 V516 G603A508-S512 WeakPolarHBondContact O-CB 3.33Å; A508-S512 PolarHBondContact O-N 3.4Å; M509-S512 PolarHBondContact O-N 3.04Å; M509-S512 PolarHBondContact O-OG 3.37Å; E510-S512 VanDerWaalsContact C-N 3.26Å; E510-S512 PolarHBondContact O-N 3.24Å; S512-E514 PolarHBondContact O-N 3.47Å; S512-E514 VanDerWaalsContact O-N 3.13Å; S512-F515 PolarHBondContact O-N 2.94Å; S512-V516 WeakPolarHBondContact O-CB 3.2Å; S512-V516 PolarHBondContact O-N 3.33Å; S512-G603 PolarHBondContact OG-N 3Å
513K96.2Very high94.8Very high37 Ų3729 Ų2916%0.16114%0.137CC..THydrogen-bonded Turntrans-66.5-8.1175.4-68.4163.7175.71700114M509 E510 Y511 G603 R604 N634M509-K513 HydrophobicContact SD-CD 4.45Å; M509-K513 WeakPolarHBondContact SD-CE 3.2Å; E510-K513 VanDerWaalsContact O-CB 3.31Å; E510-K513 WeakPolarHBondContact O-CB 3.49Å; E510-K513 PolarHBondContact O-N 3.02Å; E510-K513 VanDerWaalsContact O-N 3.12Å; E510-K513 WeakPolarHBondContact OE1-CD 3.26Å; E510-K513 IonicContact OE1-NZ 2.71Å; E510-K513 PolarHBondContact OE1-NZ 2.83Å; E510-K513 IonicContact OE2-NZ 2.64Å; E510-K513 PolarHBondContact OE2-NZ 3.15Å; Y511-K513 PolarHBondContact O-N 3.38Å; Y511-K513 VanDerWaalsContact O-N 3.15Å; K513-G603 WeakPolarHBondContact CG-O 3.33Å; K513-R604 HydrophobicContact CB-CG 3.89Å; K513-R604 HydrophobicContact CG-CG 4.1Å; K513-R604 PolarHBondContact O-NE 3.29Å; K513-R604 PolarHBondContact O-NH2 2.8Å; K513-N634 WeakPolarHBondContact CE-OD1 3.38Å; K513-N634 PolarHBondContact NZ-OD1 2.91Å
514E96Very high94.7Very high123 Ų12329 Ų2958%0.57514%0.137SC*.THydrogen-bonded Turntrans-76.5-34.6172-66.2-174.1172.400113.1R486 Y511 S512R486-E514 IonicContact CZ-OE2 3.23Å; R486-E514 IonicContact NH1-OE2 3.25Å; R486-E514 PolarHBondContact NH1-OE2 2.99Å; R486-E514 IonicContact NH2-OE2 3.25Å; R486-E514 PolarHBondContact NH2-OE2 2.71Å; Y511-E514 PolarHBondContact O-N 3.29Å; S512-E514 PolarHBondContact O-N 3.47Å; S512-E514 VanDerWaalsContact O-N 3.13Å
515F96.5Very high94.5Very high8 Ų830 Ų304%0.03514%0.143CC..THydrogen-bonded Turntrans-128.5-23.7-169.757.7-81.9000114.8F483 R486 L492 K493 C494 Y511 S512F483-F515 HydrophobicContact CD1-CZ 4.34Å; F483-F515 HydrophobicContact CD2-CE2 4.23Å; F483-F515 AromaticContact CD2-CZ 3.86Å; F483-F515 HydrophobicContact CD2-CZ 3.86Å; F483-F515 HydrophobicContact CE1-CZ 4.39Å; F483-F515 HydrophobicContact CE2-CE2 4.44Å; F483-F515 AromaticContact CE2-CZ 3.89Å; F483-F515 HydrophobicContact CE2-CZ 3.89Å; F483-F515 HydrophobicContact CG-CZ 4.08Å; F483-F515 HydrophobicContact CZ-CZ 4.17Å; R486-F515 VanDerWaalsContact NH1-CD1 3.33Å; L492-F515 HydrophobicContact CD2-CD2 4.26Å; K493-F515 WeakPolarHBondContact CA-O 3.36Å; C494-F515 PolarHBondContact N-O 3.01Å; Y511-F515 AromaticContact CD1-CE1 3.71Å; Y511-F515 HydrophobicContact CD1-CE1 3.71Å; Y511-F515 HydrophobicContact CD1-CZ 4.28Å; Y511-F515 AromaticContact CE1-CE1 3.63Å; Y511-F515 HydrophobicContact CE1-CE1 3.63Å; Y511-F515 HydrophobicContact CE1-CZ 4.22Å; S512-F515 PolarHBondContact O-N 2.94Å
516V98.3Very high94.4Very high1 Ų131.2 Ų31.21%0.00615%0.15CC..EExtended strand (participates in β ladder)trans-93.5124.3178.2-169.60000110.6A479 C494 A496 S512 P602 G603 R604A479-V516 HydrophobicContact CB-CG1 4.41Å; A479-V516 HydrophobicContact CB-CG2 4.42Å; C494-V516 HydrophobicContact CB-CB 4.28Å; C494-V516 HydrophobicContact CB-CG1 4.17Å; C494-V516 HydrophobicContact CB-CG2 3.96Å; A496-V516 HydrophobicContact CB-CG1 3.99Å; S512-V516 WeakPolarHBondContact O-CB 3.2Å; S512-V516 PolarHBondContact O-N 3.33Å; V516-P602 HydrophobicContact CG1-CB 4.23Å; V516-P602 HydrophobicContact CG1-CG 4.4Å; V516-G603 CarbonylContact O-C 3.57Å; V516-G603 WeakPolarHBondContact O-CA 3.26Å; V516-R604 PolarHBondContact O-N 2.67Å
517T98Very high94.4Very high21 Ų2127.2 Ų27.213%0.12913%0.131CC..EExtended strand (participates in β ladder)trans-104.3120.5161.8-56.30000108V292 C494 F495 A496 I606V292-T517 HydrophobicContact CG2-CG2 3.97Å; C494-T517 PolarHBondContact O-N 2.8Å; F495-T517 WeakPolarHBondContact CA-O 3.45Å; A496-T517 PolarHBondContact N-O 2.86Å; T517-I606 HydrophobicContact CG2-CD1 3.81Å; T517-I606 HydrophobicContact CG2-CG1 4.34Å
518A97.9Very high94.3Very high0 Ų022.7 Ų22.70%011%0.106CC..EExtended strand (participates in β ladder)trans-103.7150.9178.800000111A496 P499 P602 R604 I605 I606A496-A518 HydrophobicContact CB-CB 4.4Å; A496-A518 CarbonylContact O-C 3.53Å; A496-A518 VanDerWaalsContact O-CA 3.23Å; A496-A518 WeakPolarHBondContact O-CA 3.46Å; P499-A518 HydrophobicContact CG-CB 4.08Å; A518-P602 WeakPolarHBondContact CB-O 3.27Å; A518-R604 PolarHBondContact N-O 2.82Å; A518-I605 HydrophobicContact CB-CG1 4.05Å; A518-I605 WeakPolarHBondContact O-CA 3.49Å; A518-I606 PolarHBondContact O-N 3.09Å
519V97.9Very high93.8Very high2 Ų225.6 Ų25.61%0.01212%0.122CC..EExtended strand (participates in β ladder)trans-125.5138175.5-179.70000109.2V292 A496 Y497 S498 I606 V655 L659V292-V519 HydrophobicContact CG1-CG2 3.43Å; V292-V519 VanDerWaalsContact CG1-CG2 3.43Å; A496-V519 PolarHBondContact O-N 3.39Å; Y497-V519 HydrophobicContact CD1-CB 3.75Å; Y497-V519 HydrophobicContact CD1-CG1 4.31Å; Y497-V519 HydrophobicContact CD1-CG2 3.72Å; Y497-V519 HydrophobicContact CE1-CB 4.27Å; Y497-V519 HydrophobicContact CE1-CG2 3.71Å; S498-V519 WeakPolarHBondContact CA-O 3.41Å; S498-V519 PolarHBondContact N-O 3.01Å; V519-I606 WeakPolarHBondContact CA-O 3.32Å; V519-V655 HydrophobicContact CG1-CG1 4.46Å; V519-L659 HydrophobicContact CG1-CD2 4.06Å
520V96.6Very high93Very high0 Ų026.1 Ų26.10%013%0.127CC..EExtended strand (participates in β ladder)trans-131.5136.51701780000109.1D524 P527 I605 I606 H607 V608 F637V520-D524 HydrophobicContact CG1-CB 4.21Å; V520-P527 HydrophobicContact CB-CG 4.37Å; V520-P527 HydrophobicContact CG1-CB 4.17Å; V520-P527 HydrophobicContact CG1-CG 3.85Å; V520-P527 HydrophobicContact CG2-CB 3.83Å; V520-P527 HydrophobicContact CG2-CG 3.69Å; V520-I605 HydrophobicContact CG2-CG2 4.07Å; V520-I606 PolarHBondContact N-O 3.48Å; V520-I606 VanDerWaalsContact N-O 3.07Å; V520-H607 CarbonylContact O-C 3.41Å; V520-H607 WeakPolarHBondContact O-CA 3.42Å; V520-H607 PolarHBondContact O-CD2 3.45Å; V520-V608 PolarHBondContact O-N 3.45Å; V520-F637 HydrophobicContact CB-CE1 4.18Å; V520-F637 HydrophobicContact CB-CZ 4.35Å; V520-F637 HydrophobicContact CG1-CE1 3.8Å; V520-F637 HydrophobicContact CG1-CZ 4.44Å; V520-F637 HydrophobicContact CG2-CE1 4.13Å; V520-F637 HydrophobicContact CG2-CZ 4.22Å
521L94.9Very high92.2Very high4 Ų423.6 Ų23.62%0.02112%0.117CC..EExtended strand (participates in β ladder)trans-97.8133.7172.3-175.864000110.9K523 D524 V608 Y627 E649 V654 V655L521-K523 PolarHBondContact O-N 3.06Å; L521-D524 WeakPolarHBondContact O-CB 3.39Å; L521-D524 PolarHBondContact O-N 3.38Å; L521-V608 HydrophobicContact CD1-CB 3.82Å; L521-V608 HydrophobicContact CD1-CG1 3.6Å; L521-Y627 HydrophobicContact CD1-CD1 4.47Å; L521-Y627 HydrophobicContact CD1-CE1 4.3Å; L521-E649 HydrophobicContact CD2-CB 4.11Å; L521-E649 HydrophobicContact CD2-CG 4.32Å; L521-E649 WeakPolarHBondContact CD2-O 3.23Å; L521-E649 HydrophobicContact CG-CB 4.35Å; L521-V654 HydrophobicContact CD2-CG1 3.84Å; L521-V654 WeakPolarHBondContact CD2-O 3.31Å; L521-V655 HydrophobicContact CB-CG2 4.32Å
522G92.2Very high91.4Very high0 Ų022.3 Ų22.30%012%0.118CC..THydrogen-bonded Turntrans51.5-117.8161.500000115H607 V608 E649G522-H607 PolarHBondContact O-CE1 3.37Å; G522-H607 PolarHBondContact O-NE2 2.88Å; G522-V608 PolarHBondContact N-O 2.69Å; G522-E649 WeakPolarHBondContact CA-OE2 3.48Å
523K90.1Very high90.7Very high46 Ų4622.8 Ų22.820%0.212%0.12CC..THydrogen-bonded Turntrans-11327179.9-62.1166.5-167.4150.90111.4S267 L521 L525 I641 S643 M646 E649S267-K523 WeakPolarHBondContact O-CG 3.28Å; L521-K523 PolarHBondContact O-N 3.06Å; K523-L525 PolarHBondContact O-N 2.98Å; K523-I641 HydrophobicContact CB-CG2 4.2Å; K523-I641 HydrophobicContact CD-CG2 3.96Å; K523-I641 HydrophobicContact CG-CG2 3.91Å; K523-S643 VanDerWaalsContact CD-CB 3.5Å; K523-S643 WeakPolarHBondContact CD-OG 3.48Å; K523-M646 WeakPolarHBondContact O-CB 3.27Å; K523-E649 PolarHBondContact N-OE2 3.32Å
524D91.4Very high89.8Confident0 Ų023.4 Ų23.40%013%0.125CC..  trans-43.9128.5177.4-176.1-21000111.3S498 V520 L521 V526 P527 R528 H650S498-D524 WeakPolarHBondContact CB-OD2 3.33Å; S498-D524 PolarHBondContact OG-OD2 2.99Å; V520-D524 HydrophobicContact CG1-CB 4.21Å; L521-D524 WeakPolarHBondContact O-CB 3.39Å; L521-D524 PolarHBondContact O-N 3.38Å; D524-V526 PolarHBondContact OD1-N 3.41Å; D524-P527 HydrophobicContact CB-CG 4.37Å; D524-P527 WeakPolarHBondContact OD1-CD 3.28Å; D524-R528 WeakPolarHBondContact O-CD 3.36Å; D524-H650 VanDerWaalsContact CG-ND1 3.27Å; D524-H650 WeakPolarHBondContact OD1-CB 3.48Å; D524-H650 IonicContact OD1-CG 2.72Å; D524-H650 IonicContact OD1-ND1 3.19Å; D524-H650 PolarHBondContact OD1-ND1 3.31Å; D524-H650 IonicContact OD2-CE1 3.89Å; D524-H650 IonicContact OD2-CG 2.72Å; D524-H650 IonicContact OD2-ND1 2.62Å; D524-H650 PolarHBondContact OD2-ND1 2.88Å
525L88.9Confident88.9Confident21 Ų2118.9 Ų18.911%0.1110%0.103CC..SBendtrans-69.4-39.1-176.6-176.864.8000113.1K523 R528 I529 V640 M646 L647K523-L525 PolarHBondContact O-N 2.98Å; L525-R528 CarbonylContact O-C 3.2Å; L525-R528 WeakPolarHBondContact O-CA 3.42Å; L525-R528 WeakPolarHBondContact O-CB 3.47Å; L525-R528 PolarHBondContact O-N 3.06Å; L525-I529 HydrophobicContact CD1-CD1 3.88Å; L525-I529 HydrophobicContact CD1-CG1 4.11Å; L525-I529 HydrophobicContact CD2-CD1 3.88Å; L525-I529 HydrophobicContact CG-CD1 3.58Å; L525-I529 HydrophobicContact CG-CG1 4.1Å; L525-I529 PolarHBondContact O-N 3.39Å; L525-I529 VanDerWaalsContact O-N 3.13Å; L525-V640 HydrophobicContact CD1-CG1 3.7Å; L525-M646 HydrophobicContact CB-CB 4.35Å; L525-M646 HydrophobicContact CB-CG 4.22Å; L525-M646 HydrophobicContact CD1-CE 4.33Å; L525-M646 HydrophobicContact CD1-SD 4.14Å; L525-M646 HydrophobicContact CD2-CE 4.22Å; L525-M646 PolarHBondContact N-O 3.18Å; L525-M646 VanDerWaalsContact N-O 3.13Å; L525-L647 HydrophobicContact CD2-CD2 3.65Å; L525-L647 HydrophobicContact CD2-CG 4.26Å
526V90.9Very high88.2Confident34 Ų3419.3 Ų19.321%0.20611%0.111CC..G310 helixtrans-69.2-44.4-167.6168.80000112.6P500 G501 D524 R528 I529 H650P500-V526 WeakPolarHBondContact CA-O 3.49Å; P500-V526 HydrophobicContact CB-CG1 4.07Å; G501-V526 PolarHBondContact N-O 2.96Å; D524-V526 PolarHBondContact OD1-N 3.41Å; V526-R528 PolarHBondContact O-N 3.42Å; V526-I529 PolarHBondContact O-N 3.48Å; V526-I529 VanDerWaalsContact O-N 3.09Å; V526-H650 VanDerWaalsContact CB-CE1 3.46Å; V526-H650 WeakPolarHBondContact CB-CE1 3.49Å
527P92.4Very high87.5Confident0 Ų020.5 Ų20.50%012%0.116CC..G310 helixtrans-59.5-11169.5-24.935.8000114.8P499 G501 V520 D524 F637P499-P527 VanDerWaalsContact O-CA 3.25Å; P499-P527 WeakPolarHBondContact O-CA 3.3Å; P499-P527 WeakPolarHBondContact O-CG 3.25Å; G501-P527 WeakPolarHBondContact CA-O 3.35Å; G501-P527 PolarHBondContact N-O 3.43Å; V520-P527 HydrophobicContact CB-CG 4.37Å; V520-P527 HydrophobicContact CG1-CB 4.17Å; V520-P527 HydrophobicContact CG1-CG 3.85Å; V520-P527 HydrophobicContact CG2-CB 3.83Å; V520-P527 HydrophobicContact CG2-CG 3.69Å; D524-P527 HydrophobicContact CB-CG 4.37Å; D524-P527 WeakPolarHBondContact OD1-CD 3.28Å; P527-F637 HydrophobicContact CB-CD1 4.11Å; P527-F637 VanDerWaalsContact O-CB 3.27Å; P527-F637 WeakPolarHBondContact O-CB 3.43Å
528R89.6Confident86.8Confident3 Ų321.7 Ų21.71%0.01112%0.118CC..G310 helixtrans-109.6-1.5-179.7-58.6177176.7-74.2-9.8113.4M269 D524 L525 V526 Q533 F637 E639 V640M269-R528 PolarHBondContact SD-NH2 2.85Å; D524-R528 WeakPolarHBondContact O-CD 3.36Å; L525-R528 CarbonylContact O-C 3.2Å; L525-R528 WeakPolarHBondContact O-CA 3.42Å; L525-R528 WeakPolarHBondContact O-CB 3.47Å; L525-R528 PolarHBondContact O-N 3.06Å; V526-R528 PolarHBondContact O-N 3.42Å; R528-Q533 WeakPolarHBondContact O-CB 3.3Å; R528-F637 WeakPolarHBondContact CA-O 3.38Å; R528-F637 HydrophobicContact CG-CB 4.31Å; R528-F637 HydrophobicContact CG-CD1 4.07Å; R528-E639 WeakPolarHBondContact CD-O 3.44Å; R528-E639 PolarHBondContact NH1-O 2.96Å; R528-E639 VanDerWaalsContact NH1-O 3.17Å; R528-V640 WeakPolarHBondContact O-CG2 3.08Å
529I81.6Confident86.1Confident62 Ų6228.5 Ų28.532%0.31814%0.144SC..  trans-100.1137.6174.8-74.3-176.6000111G501 G502 L525 V526G501-I529 CarbonylContact C-O 3.51Å; G501-I529 WeakPolarHBondContact CA-O 3.29Å; G501-I529 PolarHBondContact N-O 2.76Å; G501-I529 VanDerWaalsContact N-O 3.16Å; G502-I529 PolarHBondContact N-O 3.15Å; L525-I529 HydrophobicContact CD1-CD1 3.88Å; L525-I529 HydrophobicContact CD1-CG1 4.11Å; L525-I529 HydrophobicContact CD2-CD1 3.88Å; L525-I529 HydrophobicContact CG-CD1 3.58Å; L525-I529 HydrophobicContact CG-CG1 4.1Å; L525-I529 PolarHBondContact O-N 3.39Å; L525-I529 VanDerWaalsContact O-N 3.13Å; V526-I529 PolarHBondContact O-N 3.48Å; V526-I529 VanDerWaalsContact O-N 3.09Å
530G79.3Confident85.5Confident11 Ų1131.2 Ų31.211%0.11316%0.156CC..SBendtrans-174.8168.2171.200000107.1S532 Q533 L534G530-S532 PolarHBondContact O-N 2.83Å; G530-Q533 PolarHBondContact O-N 3.26Å; G530-Q533 PolarHBondContact O-OE1 2.93Å; G530-L534 VanDerWaalsContact O-CB 3.25Å; G530-L534 WeakPolarHBondContact O-CB 3.1Å; G530-L534 PolarHBondContact O-N 3.11Å
531L77.3Confident84.9Confident53 Ų5331.3 Ų31.328%0.27716%0.157SC..Hα-helixtrans-57-45.7-172.3-69.5-170.7000113.3G412 L534 E535 L593G412-L531 WeakPolarHBondContact O-CD1 3.4Å; G412-L531 WeakPolarHBondContact O-CG 3.4Å; L531-L534 PolarHBondContact O-N 3.15Å; L531-E535 PolarHBondContact O-N 2.87Å; L531-L593 HydrophobicContact CB-CD2 4.2Å; L531-L593 HydrophobicContact CD1-CD2 4.23Å; L531-L593 HydrophobicContact CD2-CD2 4.11Å; L531-L593 HydrophobicContact CG-CD2 4.42Å
532S76.6Confident84.3Confident42 Ų4232.8 Ų32.829%0.29416%0.164SC..Hα-helixtrans-69.8-36.8-17865.90000112.6G530 G536G530-S532 PolarHBondContact O-N 2.83Å; S532-G536 PolarHBondContact O-N 2.88Å; S532-G536 VanDerWaalsContact O-N 3.07Å
533Q82.1Confident83.9Confident11 Ų1134.9 Ų34.95%0.05118%0.175CC..Hα-helixtrans-67-40.1173.5-60.485.3-7.600111.1R528 G530 G536 F537 N638 V640R528-Q533 WeakPolarHBondContact O-CB 3.3Å; G530-Q533 PolarHBondContact O-N 3.26Å; G530-Q533 PolarHBondContact O-OE1 2.93Å; Q533-G536 PolarHBondContact O-N 3.48Å; Q533-F537 PolarHBondContact O-N 3.31Å; Q533-N638 PolarHBondContact NE2-OD1 3.2Å; Q533-V640 HydrophobicContact CB-CG2 4.42Å
534L77.7Confident83.7Confident50 Ų5033.1 Ų33.126%0.26217%0.169SC..Hα-helixtrans-70.8-36.6180-16673000112.1F225 G530 L531 F537 R538F225-L534 HydrophobicContact CD2-CD2 4.03Å; F225-L534 HydrophobicContact CD2-CG 4.27Å; F225-L534 HydrophobicContact CE2-CD1 4.42Å; F225-L534 HydrophobicContact CE2-CD2 3.84Å; F225-L534 HydrophobicContact CE2-CG 3.57Å; F225-L534 HydrophobicContact CZ-CD1 4.19Å; F225-L534 HydrophobicContact CZ-CD2 4.36Å; F225-L534 HydrophobicContact CZ-CG 3.82Å; G530-L534 VanDerWaalsContact O-CB 3.25Å; G530-L534 WeakPolarHBondContact O-CB 3.1Å; G530-L534 PolarHBondContact O-N 3.11Å; L531-L534 PolarHBondContact O-N 3.15Å; L534-F537 HydrophobicContact CD1-CD1 4.21Å; L534-F537 PolarHBondContact O-N 2.89Å; L534-R538 PolarHBondContact O-N 3.48Å
535E77.8Confident83.3Confident27 Ų2733.3 Ų33.313%0.12617%0.169CC..Hα-helixtrans-59.4-46.5165.7-85.9-156.9-148.100111.9L531 F537 R538 R539 L593 S594L531-E535 PolarHBondContact O-N 2.87Å; E535-F537 VanDerWaalsContact C-N 3.29Å; E535-F537 PolarHBondContact O-N 3.42Å; E535-R538 WeakPolarHBondContact O-CB 3.43Å; E535-R538 PolarHBondContact O-N 3.31Å; E535-R538 VanDerWaalsContact O-N 3.15Å; E535-R539 WeakPolarHBondContact O-CG 3.24Å; E535-R539 PolarHBondContact O-N 3.23Å; E535-R539 IonicContact OE2-CZ 3.84Å; E535-R539 IonicContact OE2-NE 2.74Å; E535-R539 PolarHBondContact OE2-NE 2.89Å; E535-R539 IonicContact OE2-NH2 3.64Å; E535-R539 PolarHBondContact OE2-NH2 2.77Å; E535-L593 HydrophobicContact CG-CD2 4.29Å; E535-L593 WeakPolarHBondContact OE1-CB 3.46Å; E535-S594 VanDerWaalsContact OE1-CA 3.25Å; E535-S594 WeakPolarHBondContact OE1-CA 3.32Å; E535-S594 PolarHBondContact OE1-N 3.33Å; E535-S594 VanDerWaalsContact OE1-N 3.07Å; E535-S594 PolarHBondContact OE1-OG 3.31Å; E535-S594 PolarHBondContact OE2-OG 2.93Å
536G81Confident83.1Confident18 Ų1838.6 Ų38.619%0.18619%0.194CC..Hα-helixtrans-55.8-47177.400000111.3S532 Q533 R539 Q540S532-G536 PolarHBondContact O-N 2.88Å; S532-G536 VanDerWaalsContact O-N 3.07Å; Q533-G536 PolarHBondContact O-N 3.48Å; G536-R539 PolarHBondContact O-N 3.25Å; G536-Q540 WeakPolarHBondContact O-CG 3.41Å; G536-Q540 PolarHBondContact O-N 3.36Å
537F83.6Confident82.7Confident26 Ų2643.8 Ų43.811%0.11421%0.209CC..Hα-helixtrans-59.8-46.5172.3170.6-106.8000112.7F225 L240 L243 Q533 L534 E535 R539 Q540 L541 V640 I642F225-F537 HydrophobicContact CZ-CD1 4.25Å; L240-F537 HydrophobicContact CD2-CE2 3.8Å; L240-F537 HydrophobicContact CD2-CZ 3.75Å; L243-F537 HydrophobicContact CD2-CD2 3.83Å; L243-F537 HydrophobicContact CD2-CE2 3.83Å; Q533-F537 PolarHBondContact O-N 3.31Å; L534-F537 HydrophobicContact CD1-CD1 4.21Å; L534-F537 PolarHBondContact O-N 2.89Å; E535-F537 VanDerWaalsContact C-N 3.29Å; E535-F537 PolarHBondContact O-N 3.42Å; F537-R539 VanDerWaalsContact C-N 3.29Å; F537-R539 PolarHBondContact O-N 3.47Å; F537-Q540 PolarHBondContact O-N 3.07Å; F537-L541 HydrophobicContact CE1-CD2 4.22Å; F537-L541 HydrophobicContact CE2-CD1 4.38Å; F537-L541 HydrophobicContact CZ-CD1 4.26Å; F537-L541 HydrophobicContact CZ-CD2 4.02Å; F537-L541 VanDerWaalsContact O-CB 3.23Å; F537-L541 WeakPolarHBondContact O-CB 3.43Å; F537-L541 PolarHBondContact O-N 2.79Å; F537-V640 HydrophobicContact CB-CB 4.43Å; F537-V640 HydrophobicContact CB-CG2 4.15Å; F537-V640 HydrophobicContact CD2-CG1 4.39Å; F537-I642 HydrophobicContact CD2-CD1 4.24Å; F537-I642 HydrophobicContact CE2-CD1 3.83Å
538R82.4Confident82.2Confident45 Ų4544.5 Ų44.517%0.1721%0.214CC..Hα-helixtrans-54.1-46.6174.4-172.2174.7160.8174.6-8.3111.3F225 D228 L534 E535 L542F225-R538 HydrophobicContact CE1-CB 4.47Å; F225-R538 HydrophobicContact CE2-CB 3.74Å; F225-R538 HydrophobicContact CE2-CG 4.19Å; F225-R538 HydrophobicContact CZ-CB 3.56Å; F225-R538 HydrophobicContact CZ-CG 4.06Å; F225-R538 VanDerWaalsContact O-CD 3.32Å; F225-R538 WeakPolarHBondContact O-CD 3.25Å; F225-R538 PolarHBondContact O-NE 3.35Å; F225-R538 PolarHBondContact O-NH1 3.07Å; D228-R538 IonicContact OD2-CZ 3.55Å; D228-R538 IonicContact OD2-NH2 3.94Å; D228-R538 PolarHBondContact OD2-NH2 2.75Å; L534-R538 PolarHBondContact O-N 3.48Å; E535-R538 WeakPolarHBondContact O-CB 3.43Å; E535-R538 PolarHBondContact O-N 3.31Å; E535-R538 VanDerWaalsContact O-N 3.15Å; R538-L542 HydrophobicContact CG-CD1 4.36Å; R538-L542 VanDerWaalsContact O-CG 3.28Å; R538-L542 WeakPolarHBondContact O-CG 3.46Å; R538-L542 PolarHBondContact O-N 2.87Å; R538-L542 VanDerWaalsContact O-N 3.11Å
539R83.4Confident81.8Confident144 Ų14450.3 Ų50.354%0.54325%0.25SS..Hα-helixtrans-65.9-45-179.7-68.3-177.7-112.4116.2-11.5111.6E535 G536 F537 D543E535-R539 WeakPolarHBondContact O-CG 3.24Å; E535-R539 PolarHBondContact O-N 3.23Å; E535-R539 IonicContact OE2-CZ 3.84Å; E535-R539 IonicContact OE2-NE 2.74Å; E535-R539 PolarHBondContact OE2-NE 2.89Å; E535-R539 IonicContact OE2-NH2 3.64Å; E535-R539 PolarHBondContact OE2-NH2 2.77Å; G536-R539 PolarHBondContact O-N 3.25Å; F537-R539 VanDerWaalsContact C-N 3.29Å; F537-R539 PolarHBondContact O-N 3.47Å; R539-D543 PolarHBondContact O-N 3.17Å; R539-D543 VanDerWaalsContact O-N 3.13Å
540Q85.1Confident81.7Confident58 Ų5850.6 Ų50.627%0.27125%0.249SC..Hα-helixtrans-63.3-44.1175.6-73-174-1.300112.9L243 G536 F537 L542 D543 V544 E639L243-Q540 HydrophobicContact CD1-CB 3.91Å; L243-Q540 HydrophobicContact CD2-CB 4.13Å; G536-Q540 WeakPolarHBondContact O-CG 3.41Å; G536-Q540 PolarHBondContact O-N 3.36Å; F537-Q540 PolarHBondContact O-N 3.07Å; Q540-L542 VanDerWaalsContact C-N 3.34Å; Q540-L542 PolarHBondContact O-N 3.37Å; Q540-D543 PolarHBondContact O-N 2.74Å; Q540-V544 PolarHBondContact O-N 3.12Å; Q540-V544 VanDerWaalsContact O-N 3.15Å; Q540-E639 PolarHBondContact NE2-OE1 3.25Å
541L84.1Confident81.9Confident3 Ų351.4 Ų51.42%0.01625%0.253CS..Hα-helixtrans-61.6-41.5180-173.371.7000111.4F226 I236 F537 V544 L545F226-L541 HydrophobicContact CE1-CD2 4.37Å; I236-L541 HydrophobicContact CG2-CD2 4.39Å; F537-L541 HydrophobicContact CE1-CD2 4.22Å; F537-L541 HydrophobicContact CE2-CD1 4.38Å; F537-L541 HydrophobicContact CZ-CD1 4.26Å; F537-L541 HydrophobicContact CZ-CD2 4.02Å; F537-L541 VanDerWaalsContact O-CB 3.23Å; F537-L541 WeakPolarHBondContact O-CB 3.43Å; F537-L541 PolarHBondContact O-N 2.79Å; L541-V544 VanDerWaalsContact O-CG2 3.23Å; L541-V544 WeakPolarHBondContact O-CG2 3.48Å; L541-L545 HydrophobicContact CG-CD1 4.26Å; L541-L545 WeakPolarHBondContact O-CB 3.38Å; L541-L545 VanDerWaalsContact O-CG 3.27Å; L541-L545 WeakPolarHBondContact O-CG 3.24Å; L541-L545 PolarHBondContact O-N 2.56Å; L541-L545 VanDerWaalsContact O-N 3.15Å
542L82.9Confident82.2Confident34 Ų3449.1 Ų49.118%0.17824%0.241CC..Hα-helixtrans-67.3-41.9175.2-71.2175.3000112.9L229 I231 R538 Q540 V544 L545 Q546L229-L542 HydrophobicContact CD1-CD1 4.06Å; L229-L542 HydrophobicContact CD1-CD2 3.77Å; L229-L542 HydrophobicContact CD1-CG 4.28Å; L229-L542 HydrophobicContact CD2-CD1 3.91Å; L229-L542 HydrophobicContact CD2-CD2 3.46Å; L229-L542 VanDerWaalsContact CD2-CD2 3.46Å; L229-L542 HydrophobicContact CD2-CG 4.32Å; L229-L542 HydrophobicContact CG-CD2 4.21Å; I231-L542 HydrophobicContact CD1-CD2 4.23Å; R538-L542 HydrophobicContact CG-CD1 4.36Å; R538-L542 VanDerWaalsContact O-CG 3.28Å; R538-L542 WeakPolarHBondContact O-CG 3.46Å; R538-L542 PolarHBondContact O-N 2.87Å; R538-L542 VanDerWaalsContact O-N 3.11Å; Q540-L542 VanDerWaalsContact C-N 3.34Å; Q540-L542 PolarHBondContact O-N 3.37Å; L542-V544 VanDerWaalsContact C-N 3.35Å; L542-V544 PolarHBondContact O-N 2.95Å; L542-L545 PolarHBondContact O-N 3.23Å; L542-Q546 WeakPolarHBondContact O-CB 3.23Å; L542-Q546 VanDerWaalsContact O-CG 3.28Å; L542-Q546 WeakPolarHBondContact O-CG 3.25Å; L542-Q546 PolarHBondContact O-N 2.95Å
543D84.7Confident82.4Confident44 Ų4451.1 Ų51.124%0.23524%0.242CC..Hα-helixtrans-62.3-40.4-179.5-174.749.5000111.6R246 R539 Q540 R547R246-D543 IonicContact CZ-OD2 2.65Å; R246-D543 IonicContact NH1-OD2 2.8Å; R246-D543 PolarHBondContact NH1-OD2 2.69Å; R246-D543 IonicContact NH2-OD2 3.33Å; R246-D543 PolarHBondContact NH2-OD2 2.71Å; R539-D543 PolarHBondContact O-N 3.17Å; R539-D543 VanDerWaalsContact O-N 3.13Å; Q540-D543 PolarHBondContact O-N 2.74Å; D543-R547 VanDerWaalsContact CG-NE 3.27Å; D543-R547 VanDerWaalsContact CG-NH2 3.31Å; D543-R547 VanDerWaalsContact O-CG 3.26Å; D543-R547 WeakPolarHBondContact O-CG 3.32Å; D543-R547 PolarHBondContact O-N 3.11Å; D543-R547 VanDerWaalsContact O-N 3.15Å; D543-R547 IonicContact OD1-CZ 3.69Å; D543-R547 IonicContact OD1-NE 2.69Å; D543-R547 PolarHBondContact OD1-NE 3.4Å; D543-R547 IonicContact OD1-NH2 3.68Å; D543-R547 PolarHBondContact OD1-NH2 2.84Å; D543-R547 IonicContact OD2-CZ 3.54Å; D543-R547 IonicContact OD2-NE 2.78Å; D543-R547 PolarHBondContact OD2-NE 3.42Å; D543-R547 IonicContact OD2-NH2 3.67Å; D543-R547 PolarHBondContact OD2-NH2 3.34Å
544V85.3Confident82.4Confident10 Ų1056.1 Ų56.16%0.06126%0.26CS..Hα-helixtrans-71-37.6174.1-60.80000113L242 L243 Q540 L541 L542 Q546 R547 S548L242-V544 HydrophobicContact CB-CB 3.88Å; L242-V544 HydrophobicContact CB-CG2 3.9Å; L242-V544 HydrophobicContact CD1-CB 4.49Å; L243-V544 HydrophobicContact CB-CG2 4.27Å; L243-V544 HydrophobicContact CD1-CG1 4.35Å; Q540-V544 PolarHBondContact O-N 3.12Å; Q540-V544 VanDerWaalsContact O-N 3.15Å; L541-V544 VanDerWaalsContact O-CG2 3.23Å; L541-V544 WeakPolarHBondContact O-CG2 3.48Å; L542-V544 VanDerWaalsContact C-N 3.35Å; L542-V544 PolarHBondContact O-N 2.95Å; V544-Q546 VanDerWaalsContact C-N 3.3Å; V544-Q546 PolarHBondContact O-N 3.07Å; V544-R547 PolarHBondContact O-N 3.13Å; V544-S548 WeakPolarHBondContact O-CB 3.37Å; V544-S548 PolarHBondContact O-N 3.02Å; V544-S548 VanDerWaalsContact O-N 3.09Å
545L83.6Confident82.6Confident3 Ų354 Ų542%0.01625%0.249CC..Hα-helixtrans-69.3-26.5176.3-74.5175.7000113.2M1 I85 I231 D235 L242 L541 L542M1-L545 HydrophobicContact CE-CB 3.89Å; M1-L545 HydrophobicContact CE-CD2 4.13Å; M1-L545 HydrophobicContact CE-CG 4.42Å; I85-L545 HydrophobicContact CD1-CD2 3.64Å; I231-L545 HydrophobicContact CD1-CD1 4.37Å; D235-L545 WeakPolarHBondContact O-CD2 3.38Å; L242-L545 HydrophobicContact CD1-CD2 4.36Å; L541-L545 HydrophobicContact CG-CD1 4.26Å; L541-L545 WeakPolarHBondContact O-CB 3.38Å; L541-L545 VanDerWaalsContact O-CG 3.27Å; L541-L545 WeakPolarHBondContact O-CG 3.24Å; L541-L545 PolarHBondContact O-N 2.56Å; L541-L545 VanDerWaalsContact O-N 3.15Å; L542-L545 PolarHBondContact O-N 3.23Å
546Q83.5Confident82.7Confident132 Ų13254.4 Ų54.462%0.61725%0.252SS*.Hα-helixtrans-79.3-37.2175.2-74.8177.719.700112.9L86 L542 V544L86-Q546 HydrophobicContact CD1-CB 4.37Å; L86-Q546 HydrophobicContact CD1-CG 4.09Å; L542-Q546 WeakPolarHBondContact O-CB 3.23Å; L542-Q546 VanDerWaalsContact O-CG 3.28Å; L542-Q546 WeakPolarHBondContact O-CG 3.25Å; L542-Q546 PolarHBondContact O-N 2.95Å; V544-Q546 VanDerWaalsContact C-N 3.3Å; V544-Q546 PolarHBondContact O-N 3.07Å
547R83.5Confident82.4Confident143 Ų14356.2 Ų56.254%0.5426%0.259SS..Hα-helixtrans-76.2-24.9177.5-66.1171.2-163.7-133.50.9113.3D543 V544 T549D543-R547 VanDerWaalsContact CG-NE 3.27Å; D543-R547 VanDerWaalsContact CG-NH2 3.31Å; D543-R547 VanDerWaalsContact O-CG 3.26Å; D543-R547 WeakPolarHBondContact O-CG 3.32Å; D543-R547 PolarHBondContact O-N 3.11Å; D543-R547 VanDerWaalsContact O-N 3.15Å; D543-R547 IonicContact OD1-CZ 3.69Å; D543-R547 IonicContact OD1-NE 2.69Å; D543-R547 PolarHBondContact OD1-NE 3.4Å; D543-R547 IonicContact OD1-NH2 3.68Å; D543-R547 PolarHBondContact OD1-NH2 2.84Å; D543-R547 IonicContact OD2-CZ 3.54Å; D543-R547 IonicContact OD2-NE 2.78Å; D543-R547 PolarHBondContact OD2-NE 3.42Å; D543-R547 IonicContact OD2-NH2 3.67Å; D543-R547 PolarHBondContact OD2-NH2 3.34Å; V544-R547 PolarHBondContact O-N 3.13Å; R547-T549 PolarHBondContact O-N 3.04Å; R547-T549 VanDerWaalsContact O-N 3.11Å
548S82.2Confident81.6Confident15 Ų1555.9 Ų55.911%0.10526%0.263CS..  trans-72.7103.7-173.91790000114.2V544 K550 I555V544-S548 WeakPolarHBondContact O-CB 3.37Å; V544-S548 PolarHBondContact O-N 3.02Å; V544-S548 VanDerWaalsContact O-N 3.09Å; S548-K550 VanDerWaalsContact C-N 3.34Å; S548-I555 WeakPolarHBondContact OG-CD1 3.38Å
549T79.4Confident80.8Confident125 Ų12554.4 Ų54.477%0.76726%0.261SS*.  trans-78.6-12.5168.855.50000114G84 R547G84-T549 WeakPolarHBondContact CA-O 3.36Å; R547-T549 PolarHBondContact O-N 3.04Å; R547-T549 VanDerWaalsContact O-N 3.11Å
550K81.4Confident79.7Confident68 Ų6849.1 Ų49.130%0.29624%0.244SC..SBendtrans-72.9147.6-176.3-64.8177.1-173.9172.80112.2G84 S548 I555 P569G84-K550 WeakPolarHBondContact CA-O 3.47Å; S548-K550 VanDerWaalsContact C-N 3.34Å; K550-I555 HydrophobicContact CB-CD1 3.99Å; K550-I555 HydrophobicContact CB-CG1 3.88Å; K550-P569 VanDerWaalsContact NZ-CD 3.31Å
551P82.8Confident78.2Confident29 Ų2952.3 Ų52.319%0.18826%0.257CS..  trans-68.7141.9172.828.8-34.3000111.1G83 W553 R554 I555G83-P551 WeakPolarHBondContact O-CA 3.29Å; G83-P551 WeakPolarHBondContact O-CB 3.4Å; P551-W553 VanDerWaalsContact C-N 3.33Å; P551-W553 PolarHBondContact O-N 3.45Å; P551-R554 HydrophobicContact CG-CB 4.04Å; P551-R554 PolarHBondContact O-N 3.39Å; P551-R554 VanDerWaalsContact O-N 3.08Å; P551-I555 PolarHBondContact O-N 2.94Å
552K83.8Confident76Confident4 Ų457 Ų572%0.01729%0.29CS..Hα-helixtrans-54.9-41.2-173.1178160.347.3178.90113.9D16 D17 I85 S234 D235 A238 R554 I555 I556D16-K552 WeakPolarHBondContact OD1-CE 3.17Å; D16-K552 IonicContact OD1-NZ 3.03Å; D16-K552 PolarHBondContact OD1-NZ 3.05Å; D16-K552 WeakPolarHBondContact OD2-CE 3.26Å; D16-K552 IonicContact OD2-NZ 3.56Å; D17-K552 WeakPolarHBondContact OD1-CE 3.41Å; D17-K552 IonicContact OD1-NZ 3.95Å; D17-K552 PolarHBondContact OD1-NZ 3.02Å; D17-K552 IonicContact OD2-NZ 3.91Å; D17-K552 PolarHBondContact OD2-NZ 3.36Å; I85-K552 HydrophobicContact CG1-CB 4.43Å; I85-K552 HydrophobicContact CG2-CD 4.47Å; S234-K552 PolarHBondContact OG-NZ 2.68Å; D235-K552 IonicContact OD1-NZ 2.62Å; D235-K552 PolarHBondContact OD1-NZ 3.03Å; A238-K552 HydrophobicContact CB-CD 4.33Å; A238-K552 HydrophobicContact CB-CG 4.07Å; K552-R554 PolarHBondContact O-N 3.3Å; K552-I555 WeakPolarHBondContact O-CB 3.08Å; K552-I555 PolarHBondContact O-N 3.05Å; K552-I556 HydrophobicContact CD-CD1 4.4Å; K552-I556 HydrophobicContact CG-CD1 3.75Å; K552-I556 HydrophobicContact CG-CG1 4.44Å; K552-I556 WeakPolarHBondContact O-CG1 3.42Å; K552-I556 PolarHBondContact O-N 2.84Å
553W80.1Confident74Confident85 Ų8558.2 Ų58.232%0.32230%0.295SS..Hα-helixtrans-59.8-41.817873.2-96.2000112.5V19 M81 P551 I555 I556 V557V19-W553 HydrophobicContact CG1-CB 4.35Å; V19-W553 HydrophobicContact CG1-CG 4.46Å; V19-W553 HydrophobicContact CG2-CB 4.49Å; M81-W553 HydrophobicContact SD-CZ2 4.42Å; P551-W553 VanDerWaalsContact C-N 3.33Å; P551-W553 PolarHBondContact O-N 3.45Å; W553-I555 VanDerWaalsContact C-N 3.29Å; W553-I555 PolarHBondContact O-N 2.73Å; W553-I556 PolarHBondContact O-N 3.43Å; W553-V557 WeakPolarHBondContact O-CB 3.33Å; W553-V557 VanDerWaalsContact O-CG2 3.29Å; W553-V557 WeakPolarHBondContact O-CG2 3.24Å; W553-V557 PolarHBondContact O-N 3.24Å
554R82.7Confident71.7Confident115 Ų11559.8 Ų59.843%0.43431%0.308SS..Hα-helixtrans-70.6-28.5-178.6-168.1176.1-176.6-172.52.5111.8P551 K552 G558 E567P551-R554 HydrophobicContact CG-CB 4.04Å; P551-R554 PolarHBondContact O-N 3.39Å; P551-R554 VanDerWaalsContact O-N 3.08Å; K552-R554 PolarHBondContact O-N 3.3Å; R554-G558 WeakPolarHBondContact O-CA 3.31Å; R554-G558 PolarHBondContact O-N 3.2Å; R554-E567 IonicContact CZ-OE2 3.22Å; R554-E567 IonicContact NE-OE2 2.78Å; R554-E567 IonicContact NH2-OE2 3.21Å; R554-E567 PolarHBondContact NH2-OE2 2.96Å
555I82.1Confident69.8Low5 Ų566.7 Ų66.73%0.02634%0.337CS..Hα-helixtrans-69.1-53.1173.5-61.1164.7000109.7I85 A238 V241 L242 S548 K550 P551 K552 W553 G558 A559I85-I555 HydrophobicContact CD1-CD1 3.71Å; I85-I555 HydrophobicContact CG1-CD1 4.06Å; A238-I555 HydrophobicContact CB-CG2 4.21Å; V241-I555 HydrophobicContact CB-CG2 3.99Å; V241-I555 HydrophobicContact CG1-CG2 3.76Å; L242-I555 HydrophobicContact CD1-CD1 4.18Å; L242-I555 HydrophobicContact CD2-CD1 4.31Å; L242-I555 HydrophobicContact CD2-CG1 4.36Å; L242-I555 HydrophobicContact CD2-CG2 4.08Å; L242-I555 HydrophobicContact CG-CD1 4.44Å; L242-I555 HydrophobicContact CG-CG2 3.86Å; S548-I555 WeakPolarHBondContact OG-CD1 3.38Å; K550-I555 HydrophobicContact CB-CD1 3.99Å; K550-I555 HydrophobicContact CB-CG1 3.88Å; P551-I555 PolarHBondContact O-N 2.94Å; K552-I555 WeakPolarHBondContact O-CB 3.08Å; K552-I555 PolarHBondContact O-N 3.05Å; W553-I555 VanDerWaalsContact C-N 3.29Å; W553-I555 PolarHBondContact O-N 2.73Å; I555-G558 CarbonylContact O-C 3.51Å; I555-G558 PolarHBondContact O-N 2.9Å; I555-A559 PolarHBondContact O-N 3.49Å; I555-A559 VanDerWaalsContact O-N 3.11Å
556I78.3Confident67.7Low37 Ų3771.7 Ų71.719%0.1937%0.372CS..Hα-helixtrans-65.5-45.8-176.8-63.6172.7000111.1I237 A238 K552 W553 G558 A559 L923I237-I556 HydrophobicContact CG2-CD1 4.4Å; I237-I556 HydrophobicContact CG2-CG1 4.37Å; A238-I556 HydrophobicContact CB-CG1 4.3Å; K552-I556 HydrophobicContact CD-CD1 4.4Å; K552-I556 HydrophobicContact CG-CD1 3.75Å; K552-I556 HydrophobicContact CG-CG1 4.44Å; K552-I556 WeakPolarHBondContact O-CG1 3.42Å; K552-I556 PolarHBondContact O-N 2.84Å; W553-I556 PolarHBondContact O-N 3.43Å; I556-G558 VanDerWaalsContact C-N 3.32Å; I556-G558 PolarHBondContact O-N 3.2Å; I556-A559 WeakPolarHBondContact O-CB 3.38Å; I556-A559 PolarHBondContact O-N 3.35Å; I556-L923 HydrophobicContact CG2-CD2 4.34Å
557V75.5Confident65.5Low55 Ų5570.1 Ų70.133%0.33337%0.365SS..Hα-helixtrans-65.2-37.1175.3179.20000111W553 A559 T560 I563W553-V557 WeakPolarHBondContact O-CB 3.33Å; W553-V557 VanDerWaalsContact O-CG2 3.29Å; W553-V557 WeakPolarHBondContact O-CG2 3.24Å; W553-V557 PolarHBondContact O-N 3.24Å; V557-A559 PolarHBondContact O-N 3.05Å; V557-A559 VanDerWaalsContact O-N 3.15Å; V557-T560 WeakPolarHBondContact O-CB 3.07Å; V557-T560 PolarHBondContact O-N 2.86Å; V557-T560 PolarHBondContact O-OG1 3.35Å; V557-I563 HydrophobicContact CG1-CD1 3.97Å
558G65.9Low63.5Low20 Ų2067.3 Ų67.321%0.20636%0.36CS..THydrogen-bonded Turntrans-69.51.3171.100000115.6Q245 R554 I555 I556Q245-G558 PolarHBondContact NE2-O 3.05Å; R554-G558 WeakPolarHBondContact O-CA 3.31Å; R554-G558 PolarHBondContact O-N 3.2Å; I555-G558 CarbonylContact O-C 3.51Å; I555-G558 PolarHBondContact O-N 2.9Å; I556-G558 VanDerWaalsContact C-N 3.32Å; I556-G558 PolarHBondContact O-N 3.2Å
559A66.1Low61.4Low14 Ų1470.2 Ų70.212%0.11638%0.379CS..THydrogen-bonded Turntrans-88.3-25.5165.800000112.7V241 I555 I556 V557 L923V241-A559 HydrophobicContact CB-CB 4.24Å; V241-A559 HydrophobicContact CG1-CB 3.66Å; V241-A559 HydrophobicContact CG2-CB 3.48Å; V241-A559 VanDerWaalsContact CG2-CB 3.48Å; I555-A559 PolarHBondContact O-N 3.49Å; I555-A559 VanDerWaalsContact O-N 3.11Å; I556-A559 WeakPolarHBondContact O-CB 3.38Å; I556-A559 PolarHBondContact O-N 3.35Å; V557-A559 PolarHBondContact O-N 3.05Å; V557-A559 VanDerWaalsContact O-N 3.15Å; A559-L923 HydrophobicContact CB-CD1 4.11Å
560T61.1Low59.5Low32 Ų3273.1 Ų73.120%0.19638%0.384CS..SBendtrans-72.8151179.473.90000110.3V557 C562V557-T560 WeakPolarHBondContact O-CB 3.07Å; V557-T560 PolarHBondContact O-N 2.86Å; V557-T560 PolarHBondContact O-OG1 3.35Å; T560-C562 PolarHBondContact O-N 3.2Å
561K52.6Low57.6Low125 Ų12577.1 Ų77.154%0.54340%0.403SS..THydrogen-bonded Turntrans-65.91-176.5-75168.4166.9160.40115.3D924K561-D924 VanDerWaalsContact CE-OD2 3.29Å; K561-D924 WeakPolarHBondContact CE-OD2 3.38Å; K561-D924 IonicContact NZ-OD1 3.42Å; K561-D924 IonicContact NZ-OD2 3.61Å; K561-D924 PolarHBondContact NZ-OD2 2.88Å
562C37.6Very low55.4Low103 Ų10381.8 Ų81.870%0.69643%0.431SS*.THydrogen-bonded Turntrans-93.9-5.4-170.3-58.80000115.2T560T560-C562 PolarHBondContact O-N 3.2Å
563I42.3Very low53.2Low58 Ų5889.3 Ų89.330%0.29747%0.466SS..SBendtrans-107.6129.1176.6-64.6-173.1000110V557 E567V557-I563 HydrophobicContact CG1-CD1 3.97Å; I563-E567 HydrophobicContact CG2-CB 3.98Å
564P36.8Very low51Low78 Ų7890.7 Ų90.751%0.50648%0.484SS..  trans-67.5147.9-177.627.6-35.2000112.3S566 E567P564-S566 PolarHBondContact O-N 2.88Å; P564-E567 PolarHBondContact O-N 3.45Å; P564-E567 VanDerWaalsContact O-N 3.08Å
565K44.7Very low48.8Very low155 Ų15591 Ų9167%0.67450%0.499SS*.G310 helixtrans-55.5-23.2-177.2-63.2167.9-173.3161.60113.7E567 L568K565-E567 VanDerWaalsContact C-N 3.3Å; K565-E567 PolarHBondContact O-N 3.28Å; K565-L568 PolarHBondContact O-N 3.45Å
566S39.2Very low46.3Very low107 Ų10796 Ų9675%0.74853%0.529SS*.G310 helixtrans-73.4-8.1179.252.80000115.4P564P564-S566 PolarHBondContact O-N 2.88Å
567E37.2Very low44.1Very low100 Ų100101.8 Ų101.847%0.46756%0.56SS.*G310 helixtrans-90.8-3.3170.2-96.3-158-129.100113.9R554 I563 P564 K565R554-E567 IonicContact CZ-OE2 3.22Å; R554-E567 IonicContact NE-OE2 2.78Å; R554-E567 IonicContact NH2-OE2 3.21Å; R554-E567 PolarHBondContact NH2-OE2 2.96Å; I563-E567 HydrophobicContact CG2-CB 3.98Å; P564-E567 PolarHBondContact O-N 3.45Å; P564-E567 VanDerWaalsContact O-N 3.08Å; K565-E567 VanDerWaalsContact C-N 3.3Å; K565-E567 PolarHBondContact O-N 3.28Å
568L41.5Very low42.4Very low83 Ų83102.6 Ų102.644%0.43557%0.573SS.*SBendtrans-77.4126166.2-85.265.4000108.3K565K565-L568 PolarHBondContact O-N 3.45Å
569P39Very low40.7Very low77 Ų77106 Ų10650%0.559%0.593SS.*PPolyproline II helixtrans-61.8138163.8-15.129.3000109.1K550 E571K550-P569 VanDerWaalsContact NZ-CD 3.31Å; P569-E571 PolarHBondContact O-N 3.49Å
570E38.7Very low39.1Very low186 Ų186111.7 Ų111.787%0.86963%0.627SS**PPolyproline II helixtrans-57.3120.8145.5-66.8174.8121.300106.8V572E570-V572 PolarHBondContact O-N 2.91Å; E570-V572 VanDerWaalsContact O-N 3.17Å
571E41.7Very low37.6Very low151 Ų151119.9 Ų119.971%0.70665%0.654SS**  trans-69.9110.1162.4-72.4-166.5163.800106.2P569 E573P569-E571 PolarHBondContact O-N 3.49Å; E571-E573 PolarHBondContact O-N 3.23Å
572V36.5Very low36.9Very low127 Ų127120.9 Ų120.977%0.7767%0.665SS**  trans-54.4113.7168.61750000107.1E570 V574E570-V572 PolarHBondContact O-N 2.91Å; E570-V572 VanDerWaalsContact O-N 3.17Å; V572-V574 VanDerWaalsContact C-N 3.3Å; V572-V574 PolarHBondContact O-N 3.34Å
573E38.1Very low36.5Very low162 Ų162127.6 Ų127.676%0.75768%0.676SS**  trans-64.493.2174.7-77.1-153.713000109.4E571 T575E571-E573 PolarHBondContact O-N 3.23Å; E573-T575 VanDerWaalsContact C-N 3.25Å; E573-T575 PolarHBondContact O-N 3.04Å; E573-T575 PolarHBondContact O-OG1 3.11Å; E573-T575 VanDerWaalsContact O-OG1 3.13Å
574V34Very low36Very low115 Ų115129.1 Ų129.170%0.69769%0.687SS**  trans-67.196.2160.4-1710000105.7V572 T576V572-V574 VanDerWaalsContact C-N 3.3Å; V572-V574 PolarHBondContact O-N 3.34Å; V574-T576 HydrophobicContact CG1-CG2 4Å; V574-T576 PolarHBondContact O-N 3.16Å
575T34.8Very low35.6Very low121 Ų121134.3 Ų134.374%0.74271%0.705SS**  trans-72.565.1-171.7-17.50000110.8E573 L577E573-T575 VanDerWaalsContact C-N 3.25Å; E573-T575 PolarHBondContact O-N 3.04Å; E573-T575 PolarHBondContact O-OG1 3.11Å; E573-T575 VanDerWaalsContact O-OG1 3.13Å; T575-L577 VanDerWaalsContact C-N 3.31Å; T575-L577 PolarHBondContact O-N 2.79Å
576T31.4Very low35.6Very low109 Ų109131.2 Ų131.267%0.66970%0.701SS**  trans-70.588.2179.153.70000110.3V574 A578V574-T576 HydrophobicContact CG1-CG2 4Å; V574-T576 PolarHBondContact O-N 3.16Å; T576-A578 PolarHBondContact O-N 3.2Å
577L32.3Very low35.2Very low159 Ų159129.9 Ų129.983%0.83269%0.691SS**THydrogen-bonded Turntrans-39.1113.7174.4-159.9172.9000111.7T575 S579T575-L577 VanDerWaalsContact C-N 3.31Å; T575-L577 PolarHBondContact O-N 2.79Å; L577-S579 PolarHBondContact O-N 3.32Å
578A37.9Very low35.1Very low73 Ų73130.2 Ų130.260%0.60370%0.696SS**THydrogen-bonded Turntrans34.364166.700000117.4T576 T580T576-A578 PolarHBondContact O-N 3.2Å; A578-T580 PolarHBondContact O-N 2.83Å
579S30.6Very low35Very low91 Ų91130.5 Ų130.564%0.63670%0.697SS**  trans-7750161.2-157.10000112.2L577 R581L577-S579 PolarHBondContact O-N 3.32Å; S579-R581 PolarHBondContact O-N 3.17Å
580T33.3Very low35Very low134 Ų134130.3 Ų130.382%0.82270%0.695SS**  trans-75.443.4167.9-41.90000109.9A578A578-T580 PolarHBondContact O-N 2.83Å
581R30.3Very low35Very low204 Ų204127.6 Ų127.677%0.7769%0.685SS**  trans-105.485.9179.6-76-167.7174.8-158.7-0.2110.1S579 W583S579-R581 PolarHBondContact O-N 3.17Å; R581-W583 PolarHBondContact O-N 2.81Å
582L36.4Very low34.9Very low145 Ų145124.1 Ų124.176%0.75968%0.682SS**  trans36.264.9130.5-162.572.1000116.1T584L582-T584 HydrophobicContact CD1-CG2 3.84Å; L582-T584 VanDerWaalsContact CD1-OG1 3.25Å; L582-T584 WeakPolarHBondContact CD1-OG1 3.07Å; L582-T584 VanDerWaalsContact CG-OG1 3.31Å; L582-T584 WeakPolarHBondContact CG-OG1 3.43Å; L582-T584 PolarHBondContact O-N 3.13Å; L582-T584 VanDerWaalsContact O-N 3.07Å
583W29.7Very low35.3Very low245 Ų245120.8 Ų120.893%0.92866%0.66SS**  trans-81.347.5164.1-7597.7000111.4R581R581-W583 PolarHBondContact O-N 2.81Å
584T32.8Very low35.3Very low89 Ų89116.8 Ų116.855%0.54665%0.65SS.*  trans-92.695.3171.255.30000109.7L582L582-T584 HydrophobicContact CD1-CG2 3.84Å; L582-T584 VanDerWaalsContact CD1-OG1 3.25Å; L582-T584 WeakPolarHBondContact CD1-OG1 3.07Å; L582-T584 VanDerWaalsContact CG-OG1 3.31Å; L582-T584 WeakPolarHBondContact CG-OG1 3.43Å; L582-T584 PolarHBondContact O-N 3.13Å; L582-T584 VanDerWaalsContact O-N 3.07Å
585H28.3Very low35.9Very low187 Ų187114.9 Ų114.987%0.86665%0.646SS**  trans-156.8151.8149-94.6-47.1000109.9
586P43Very low37Very low91 Ų91111 Ų11159%0.59162%0.624SS**  -120.2169.7-126.135.9-23.1000114.5
587S30.8Very low38.9Very low78 Ų78109.1 Ų109.155%0.54561%0.612SS.*  trans-147.263.1154.437.60000110.8L589S587-L589 VanDerWaalsContact C-N 3.29Å; S587-L589 PolarHBondContact O-N 3.32Å
588D35.1Very low41.1Very low108 Ų108104.8 Ų104.858%0.57859%0.593SS**SBendtrans59.712.2137.1-45.6-18.9000120
589L39.1Very low43.6Very low88 Ų88101.9 Ų101.946%0.46157%0.568SS.*SBendtrans-140.7-1.6157.8-14080.5000115.3R227 S587 I591 A592R227-L589 VanDerWaalsContact NH1-CD2 3.32Å; S587-L589 VanDerWaalsContact C-N 3.29Å; S587-L589 PolarHBondContact O-N 3.32Å; L589-I591 PolarHBondContact O-N 3.39Å; L589-I591 VanDerWaalsContact O-N 3.17Å; L589-A592 PolarHBondContact O-N 3.16Å
590T39.2Very low46.5Very low73 Ų7398.4 Ų98.445%0.44854%0.541SS..Hα-helixtrans-62.2-19.4171.739.50000113.2A592 L593 S594T590-A592 VanDerWaalsContact C-N 3.27Å; T590-A592 PolarHBondContact O-N 2.7Å; T590-L593 PolarHBondContact O-N 2.78Å; T590-S594 WeakPolarHBondContact O-CB 3.37Å; T590-S594 PolarHBondContact O-N 2.88Å; T590-S594 PolarHBondContact O-OG 3.13Å
591I38.9Very low49.5Very low130 Ų13092.1 Ų92.167%0.66750%0.502SS*.Hα-helixtrans-63.4-30.1178.8-61173.4000112.1L589 A595L589-I591 PolarHBondContact O-N 3.39Å; L589-I591 VanDerWaalsContact O-N 3.17Å; I591-A595 WeakPolarHBondContact O-CB 3.35Å
592A41.2Very low52.6Low77 Ų7782.4 Ų82.464%0.63647%0.466SS*.Hα-helixtrans-69.8-46.5179.900000112.4L589 T590L589-A592 PolarHBondContact O-N 3.16Å; T590-A592 VanDerWaalsContact C-N 3.27Å; T590-A592 PolarHBondContact O-N 2.7Å
593L43Very low55.5Low57 Ų5775.5 Ų75.530%0.29843%0.429SS..Hα-helixtrans-76.4-43.6-178-103.6151.8000112L531 E535 T590 A595 S596L531-L593 HydrophobicContact CB-CD2 4.2Å; L531-L593 HydrophobicContact CD1-CD2 4.23Å; L531-L593 HydrophobicContact CD2-CD2 4.11Å; L531-L593 HydrophobicContact CG-CD2 4.42Å; E535-L593 HydrophobicContact CG-CD2 4.29Å; E535-L593 WeakPolarHBondContact OE1-CB 3.46Å; T590-L593 PolarHBondContact O-N 2.78Å; L593-A595 PolarHBondContact O-N 3.05Å; L593-A595 VanDerWaalsContact O-N 3.1Å; L593-S596 WeakPolarHBondContact O-CB 3.27Å; L593-S596 PolarHBondContact O-N 3.21Å; L593-S596 PolarHBondContact O-OG 3.27Å
594S39.9Very low58.7Low78 Ų7870.4 Ų70.455%0.54541%0.41SS..THydrogen-bonded Turntrans-763.2-177.3-55.60000114.5E535 T590E535-S594 VanDerWaalsContact OE1-CA 3.25Å; E535-S594 WeakPolarHBondContact OE1-CA 3.32Å; E535-S594 PolarHBondContact OE1-N 3.33Å; E535-S594 VanDerWaalsContact OE1-N 3.07Å; E535-S594 PolarHBondContact OE1-OG 3.31Å; E535-S594 PolarHBondContact OE2-OG 2.93Å; T590-S594 WeakPolarHBondContact O-CB 3.37Å; T590-S594 PolarHBondContact O-N 2.88Å; T590-S594 PolarHBondContact O-OG 3.13Å
595A45Very low61.7Low75 Ų7566.2 Ų66.262%0.6238%0.384SS*.THydrogen-bonded Turntrans-96.7-2.7169.200000113.4I591 L593 T597I591-A595 WeakPolarHBondContact O-CB 3.35Å; L593-A595 PolarHBondContact O-N 3.05Å; L593-A595 VanDerWaalsContact O-N 3.1Å; A595-T597 PolarHBondContact O-N 2.84Å
596S59.7Low64.9Low39 Ų3957.4 Ų57.427%0.27334%0.343SS..PPolyproline II helixtrans-63.3124.9-179.753.20000112.1L593L593-S596 WeakPolarHBondContact O-CB 3.27Å; L593-S596 PolarHBondContact O-N 3.21Å; L593-S596 PolarHBondContact O-OG 3.27Å
597T70.2Confident67.4Low70 Ų7053 Ų5343%0.42932%0.315SS..PPolyproline II helixtrans-61.8136.1174.4-51.50000109.6L427 A595 L599L427-T597 HydrophobicContact CD1-CG2 4.35Å; A595-T597 PolarHBondContact O-N 2.84Å; T597-L599 PolarHBondContact O-N 3.18Å; T597-L599 VanDerWaalsContact O-N 3.16Å
598P78.9Confident70.4Confident68 Ų6849.4 Ų49.444%0.44229%0.29SS..PPolyproline II helixtrans-63.6119.7176.125.9-33.8000110.4Y600P598-Y600 HydrophobicContact CB-CE2 4.29Å
599L89.3Confident73.1Confident12 Ų1244.2 Ų44.26%0.06326%0.262CS..  trans-105.9151.7173.8-57.4-179.7000110.1A414 L427 G501 G502 L504 T597A414-L599 HydrophobicContact CB-CD1 4.17Å; L427-L599 HydrophobicContact CB-CD2 4.34Å; G501-L599 CarbonylContact O-C 3.59Å; G502-L599 VanDerWaalsContact C-CB 3.41Å; G502-L599 VanDerWaalsContact O-CD1 3.24Å; G502-L599 WeakPolarHBondContact O-CD1 3.49Å; L504-L599 CarbonylContact O-C 3.56Å; L504-L599 VanDerWaalsContact O-CA 3.25Å; L504-L599 WeakPolarHBondContact O-CA 3.47Å; T597-L599 PolarHBondContact O-N 3.18Å; T597-L599 VanDerWaalsContact O-N 3.16Å
600Y93.1Very high75.3Confident19 Ų1940.3 Ų40.38%0.07524%0.242CC..BIsolated β-bridgetrans-131.5154.2-169.7-61-80.3000112.3G501 L504 E506 P598 K635G501-Y600 CarbonylContact O-C 3.58Å; G501-Y600 WeakPolarHBondContact O-CA 3.47Å; G501-Y600 PolarHBondContact O-N 3.13Å; L504-Y600 PolarHBondContact N-O 3.02Å; L504-Y600 PolarHBondContact O-N 2.77Å; E506-Y600 HydrophobicContact CB-CD2 4.26Å; E506-Y600 HydrophobicContact CB-CE2 3.97Å; E506-Y600 HydrophobicContact CG-CE2 4.38Å; P598-Y600 HydrophobicContact CB-CE2 4.29Å; Y600-K635 HydrophobicContact CD1-CG 4.19Å; Y600-K635 HydrophobicContact CE1-CB 4.29Å; Y600-K635 HydrophobicContact CE1-CD 4.36Å; Y600-K635 HydrophobicContact CE1-CG 3.85Å
601P95.3Very high77.2Confident1 Ų139 Ų391%0.00623%0.232CC..  trans-67.3147173.927-34000111.2G501 M509 I605 N634 F637G501-P601 WeakPolarHBondContact O-CD 3.36Å; G501-P601 VanDerWaalsContact O-N 3.09Å; M509-P601 VanDerWaalsContact CG-O 3.32Å; M509-P601 WeakPolarHBondContact CG-O 3.35Å; P601-I605 HydrophobicContact CB-CD1 4.21Å; P601-I605 HydrophobicContact CG-CD1 3.82Å; P601-N634 WeakPolarHBondContact CD-O 3.37Å; P601-N634 HydrophobicContact CG-CB 4.46Å; P601-N634 PolarHBondContact O-ND2 3.42Å; P601-F637 HydrophobicContact CG-CB 4.45Å; P601-F637 HydrophobicContact CG-CD2 4.17Å; P601-F637 HydrophobicContact CG-CG 4.49Å
602P96.3Very high78.5Confident0 Ų038.2 Ų38.20%023%0.225CC..  trans-80162.4-171.434.7-38.4000113.7A479 P499 L503 L504 V516 A518A479-P602 HydrophobicContact CB-CB 3.95Å; A479-P602 HydrophobicContact CB-CG 3.86Å; P499-P602 HydrophobicContact CB-CG 3.86Å; P499-P602 HydrophobicContact CG-CG 3.95Å; L503-P602 HydrophobicContact CD2-CB 3.99Å; L503-P602 HydrophobicContact CD2-CG 3.57Å; L504-P602 HydrophobicContact CD1-CB 3.76Å; V516-P602 HydrophobicContact CG1-CB 4.23Å; V516-P602 HydrophobicContact CG1-CG 4.4Å; A518-P602 WeakPolarHBondContact CB-O 3.27Å
603G96.2Very high79.4Confident0 Ų036.6 Ų36.60%021%0.208CC..SBendtrans73-170.7161.100000115.9S512 K513 V516 N634S512-G603 PolarHBondContact OG-N 3Å; K513-G603 WeakPolarHBondContact CG-O 3.33Å; V516-G603 CarbonylContact O-C 3.57Å; V516-G603 WeakPolarHBondContact O-CA 3.26Å; G603-N634 PolarHBondContact O-ND2 3.17Å
604R96.4Very high79.8Confident138 Ų13838.3 Ų38.352%0.52123%0.23SC..EExtended strand (participates in β ladder)trans-82.9117169.3-56.7-175.2-165.3-145.1-4.5108.5K513 V516 A518 W631K513-R604 HydrophobicContact CB-CG 3.89Å; K513-R604 HydrophobicContact CG-CG 4.1Å; K513-R604 PolarHBondContact O-NE 3.29Å; K513-R604 PolarHBondContact O-NH2 2.8Å; V516-R604 PolarHBondContact O-N 2.67Å; A518-R604 PolarHBondContact N-O 2.82Å; R604-W631 HydrophobicContact CB-CE3 4.49Å; R604-W631 HydrophobicContact CB-CZ3 3.9Å
605I96.2Very high80.2Confident1 Ų140.4 Ų40.41%0.00523%0.232CC..EExtended strand (participates in β ladder)trans-86.1124.2-175.7-59.2175.2000110.5A518 V520 P601 H607 G632 N634 F637A518-I605 HydrophobicContact CB-CG1 4.05Å; A518-I605 WeakPolarHBondContact O-CA 3.49Å; V520-I605 HydrophobicContact CG2-CG2 4.07Å; P601-I605 HydrophobicContact CB-CD1 4.21Å; P601-I605 HydrophobicContact CG-CD1 3.82Å; I605-H607 HydrophobicContact CG2-CB 4.47Å; I605-G632 PolarHBondContact O-N 3.24Å; I605-N634 HydrophobicContact CD1-CB 4.25Å; I605-F637 HydrophobicContact CD1-CD2 3.96Å; I605-F637 HydrophobicContact CD1-CE2 3.57Å; I605-F637 HydrophobicContact CD1-CZ 4.42Å; I605-F637 HydrophobicContact CG2-CE2 4.11Å; I605-F637 HydrophobicContact CG2-CZ 4.05Å
606I96.3Very high79.9Confident2 Ų244.1 Ų44.11%0.0124%0.236CC..EExtended strand (participates in β ladder)trans-97105.6163-59.1173.9000106.8Y289 V292 T517 A518 V519 V520 A629 W631Y289-I606 HydrophobicContact CD2-CG2 4.46Å; Y289-I606 HydrophobicContact CE2-CG2 3.99Å; V292-I606 HydrophobicContact CG2-CD1 4.14Å; T517-I606 HydrophobicContact CG2-CD1 3.81Å; T517-I606 HydrophobicContact CG2-CG1 4.34Å; A518-I606 PolarHBondContact O-N 3.09Å; V519-I606 WeakPolarHBondContact CA-O 3.32Å; V520-I606 PolarHBondContact N-O 3.48Å; V520-I606 VanDerWaalsContact N-O 3.07Å; I606-A629 HydrophobicContact CG2-CB 3.97Å; I606-W631 HydrophobicContact CD1-CH2 4.21Å; I606-W631 HydrophobicContact CD1-CZ3 4.24Å; I606-W631 HydrophobicContact CG1-CE3 4.06Å; I606-W631 HydrophobicContact CG1-CH2 3.99Å; I606-W631 HydrophobicContact CG1-CZ3 3.56Å
607H95.4Very high78.9Confident0 Ų047.1 Ų47.10%026%0.256CS..EExtended strand (participates in β ladder)trans-91.1113.7176.6-165.5171.1000108.7M269 V520 G522 I605 V609 I630 F637M269-H607 WeakPolarHBondContact CG-CE1 3.23Å; V520-H607 CarbonylContact O-C 3.41Å; V520-H607 WeakPolarHBondContact O-CA 3.42Å; V520-H607 PolarHBondContact O-CD2 3.45Å; G522-H607 PolarHBondContact O-CE1 3.37Å; G522-H607 PolarHBondContact O-NE2 2.88Å; I605-H607 HydrophobicContact CG2-CB 4.47Å; H607-V609 PolarHBondContact O-N 3.05Å; H607-I630 HydrophobicContact CB-CG1 3.91Å; H607-I630 PolarHBondContact N-O 3.37Å; H607-I630 PolarHBondContact O-N 3.06Å; H607-F637 AromaticContact CE1-CE1 3.98Å; H607-F637 AromaticContact ND1-CZ 3.73Å
608V94.6Very high77.6Confident1 Ų149.8 Ų49.81%0.00628%0.276CS..EExtended strand (participates in β ladder)trans-81.5101.8170.2179.70000108V520 L521 G522 Y627 F628 L659 V662V520-V608 PolarHBondContact O-N 3.45Å; L521-V608 HydrophobicContact CD1-CB 3.82Å; L521-V608 HydrophobicContact CD1-CG1 3.6Å; G522-V608 PolarHBondContact N-O 2.69Å; V608-Y627 HydrophobicContact CG1-CD1 4Å; V608-F628 CarbonylContact C-O 3.39Å; V608-F628 WeakPolarHBondContact CA-O 3.45Å; V608-L659 HydrophobicContact CG2-CD2 4.01Å; V608-V662 HydrophobicContact CG1-CG2 3.72Å; V608-V662 HydrophobicContact CG2-CG2 4.47Å
609V91Very high75.9Confident0 Ų052.4 Ų52.40%030%0.295CS..EExtended strand (participates in β ladder)trans-98.7149.5175.7-62.40000110.2L266 H607 F628 I630L266-V609 HydrophobicContact CB-CB 4.09Å; L266-V609 HydrophobicContact CB-CG2 4.06Å; L266-V609 HydrophobicContact CD1-CG2 4.15Å; H607-V609 PolarHBondContact O-N 3.05Å; V609-F628 HydrophobicContact CG2-CB 4.37Å; V609-F628 PolarHBondContact N-O 2.69Å; V609-F628 PolarHBondContact O-N 3.13Å; V609-F628 VanDerWaalsContact O-O 3.12Å; V609-I630 HydrophobicContact CG1-CD1 3.86Å; V609-I630 HydrophobicContact CG1-CG1 4.23Å; V609-I630 HydrophobicContact CG2-CD1 4.24Å; V609-I630 HydrophobicContact CG2-CG1 4.39Å; V609-I630 HydrophobicContact CG2-CG2 4.19Å
610H85.4Confident73.7Confident6 Ų655.4 Ų55.43%0.02832%0.316CS..EExtended strand (participates in β ladder)trans-121.8147.1177.154.4-112.9000110.7S267 H612 T626 Y627 E649S267-H610 PolarHBondContact OG-CD2 2.8Å; S267-H610 PolarHBondContact OG-CE1 2.83Å; S267-H610 VanDerWaalsContact OG-CE1 3.3Å; S267-H610 PolarHBondContact OG-N 3.22Å; S267-H610 PolarHBondContact OG-ND1 2.77Å; S267-H610 PolarHBondContact OG-NE2 3.41Å; S267-H610 VanDerWaalsContact OG-NE2 3.12Å; S267-H610 PolarHBondContact OG-O 2.78Å; H610-H612 AromaticContact CD2-CE1 3.42Å; H610-H612 PolarHBondContact CD2-CE1 3Å; H610-H612 VanDerWaalsContact CD2-CE1 3.42Å; H610-H612 AromaticContact CD2-ND1 3.31Å; H610-H612 PolarHBondContact CD2-ND1 3.15Å; H610-H612 VanDerWaalsContact CD2-ND1 3.31Å; H610-H612 AromaticContact NE2-CE1 3.49Å; H610-H612 PolarHBondContact NE2-CE1 3.4Å; H610-H612 AromaticContact NE2-ND1 3.68Å; H610-T626 CarbonylContact C-O 3.54Å; H610-T626 VanDerWaalsContact CA-O 3.23Å; H610-T626 WeakPolarHBondContact CA-O 3.24Å; H610-Y627 HydrophobicContact CB-CD1 4.08Å; H610-Y627 HydrophobicContact CB-CD2 4.37Å; H610-Y627 HydrophobicContact CB-CE1 4.17Å; H610-Y627 HydrophobicContact CB-CE2 4.44Å; H610-Y627 HydrophobicContact CB-CG 4.18Å; H610-E649 IonicContact CE1-OE1 2.73Å; H610-E649 PolarHBondContact CE1-OE1 3.21Å; H610-E649 VanDerWaalsContact CE1-OE1 3.31Å; H610-E649 IonicContact CE1-OE2 3.42Å; H610-E649 IonicContact NE2-OE1 3.54Å
611N77.9Confident71.4Confident45 Ų4564 Ų6424%0.24136%0.357CS..EExtended strand (participates in β ladder)trans-101.2123.4164.2-164.921.3000109.4L266 P625 T626 F628L266-N611 HydrophobicContact CD2-CB 3.7Å; N611-P625 WeakPolarHBondContact O-CA 3.26Å; N611-T626 PolarHBondContact N-O 3.25Å; N611-T626 PolarHBondContact O-N 2.78Å; N611-T626 VanDerWaalsContact O-N 3.09Å; N611-F628 HydrophobicContact CB-CE2 4.38Å
612H68.3Low69.5Low113 Ų11370.6 Ų70.652%0.52339%0.387SS..PPolyproline II helixtrans-86.5124.3164.7-75.180000107.2H610H610-H612 AromaticContact CD2-CE1 3.42Å; H610-H612 PolarHBondContact CD2-CE1 3Å; H610-H612 VanDerWaalsContact CD2-CE1 3.42Å; H610-H612 AromaticContact CD2-ND1 3.31Å; H610-H612 PolarHBondContact CD2-ND1 3.15Å; H610-H612 VanDerWaalsContact CD2-ND1 3.31Å; H610-H612 AromaticContact NE2-CE1 3.49Å; H610-H612 PolarHBondContact NE2-CE1 3.4Å; H610-H612 AromaticContact NE2-ND1 3.68Å
613P59Low67.8Low43 Ų4376.2 Ų76.228%0.27941%0.413SS..PPolyproline II helixtrans-58.7152.4171.827-34.3000110E615 E623P613-E615 PolarHBondContact O-N 2.93Å; P613-E623 HydrophobicContact CB-CB 4.22Å; P613-E623 HydrophobicContact CG-CB 3.87Å; P613-E623 WeakPolarHBondContact CG-O 3.15Å
614A52.1Low66.4Low93 Ų9381.4 Ų81.477%0.76944%0.438SS*.PPolyproline II helixtrans-60.8124.1177.400000109.6Q616A614-Q616 PolarHBondContact O-N 3.49Å
615E47.1Very low65.3Low123 Ų12376.8 Ų76.858%0.57543%0.426SS*.  trans-58.994-178.8-66.7169129.800110.6P613P613-E615 PolarHBondContact O-N 2.93Å
616Q39.1Very low64.6Low152 Ų15277.8 Ų77.871%0.7143%0.432SS*.  trans-69.7164.9163.5-83.3-175.2-20.500110.2A614A614-Q616 PolarHBondContact O-N 3.49Å
617C38.8Very low64.2Low102 Ų10279.2 Ų79.269%0.68944%0.437SS*.  trans-57.2152.4-169-161.20000112.7C619 C620C617-C619 PolarHBondContact O-N 2.85Å; C617-C620 PolarHBondContact O-N 3.49Å
618C43.2Very low63.8Low127 Ų12779.7 Ų79.786%0.85844%0.439SS*.THydrogen-bonded Turntrans-63.812.2-167.6-53.50000116.8
619C42.9Very low63.7Low123 Ų12379.9 Ų79.983%0.83144%0.441SS*.THydrogen-bonded Turntrans-114.8-3.3-179.1-56.30000113.4C617C617-C619 PolarHBondContact O-N 2.85Å
620C43.3Very low63.7Low75 Ų7580.4 Ų80.451%0.50744%0.444SS..SBendtrans-103.4149177.5-60.20000111.4C617 Q622C617-C620 PolarHBondContact O-N 3.49Å; C620-Q622 PolarHBondContact O-N 3.39Å
621E43.9Very low64.1Low199 Ų19983.3 Ų83.393%0.9346%0.455SS*.PPolyproline II helixtrans-59.8130.9170.5-63.1-174.2144.800110.3
622Q55.4Low64.7Low140 Ų14082 Ų8265%0.65445%0.451SS*.PPolyproline II helixtrans-85.5119.9-178.6-61.2-167.8-34.900109.8C620 E624C620-Q622 PolarHBondContact O-N 3.39Å; Q622-E624 PolarHBondContact O-N 3.16Å
623E61.3Low65.8Low117 Ų11780.6 Ų80.655%0.54745%0.448SS..PPolyproline II helixtrans-51132.2171.7-87-169.6168.400110.3P613 K678P613-E623 HydrophobicContact CB-CB 4.22Å; P613-E623 HydrophobicContact CG-CB 3.87Å; P613-E623 WeakPolarHBondContact CG-O 3.15Å; E623-K678 IonicContact OE1-NZ 2.77Å; E623-K678 PolarHBondContact OE1-NZ 3.21Å; E623-K678 IonicContact OE2-NZ 2.89Å; E623-K678 PolarHBondContact OE2-NZ 3.38Å
624E65.9Low67.4Low109 Ų10978.8 Ų78.851%0.50944%0.436SS..PPolyproline II helixtrans-55.3133.2175.1-66-171.3125.200110.8Q622 T626 K668Q622-E624 PolarHBondContact O-N 3.16Å; E624-T626 PolarHBondContact O-N 2.85Å; E624-K668 IonicContact OE2-NZ 2.64Å; E624-K668 PolarHBondContact OE2-NZ 3.06Å
625P73.9Confident69.2Low41 Ų4178.1 Ų78.127%0.26642%0.416SS..PPolyproline II helixtrans-59.1134.5175.322.5-31000110.5N611 Y627N611-P625 WeakPolarHBondContact O-CA 3.26Å; P625-Y627 HydrophobicContact CB-CE2 4.23Å; P625-Y627 HydrophobicContact CG-CE2 4.11Å; P625-Y627 VanDerWaalsContact O-CD2 3.23Å; P625-Y627 WeakPolarHBondContact O-CD2 3.09Å; P625-Y627 WeakPolarHBondContact O-CE2 3.05Å
626T81Confident71.2Confident22 Ų2274 Ų7414%0.13540%0.402CS..EExtended strand (participates in β ladder)trans-97.4129.7-173.549.70000110.7H610 N611 E624 F628 K670H610-T626 CarbonylContact C-O 3.54Å; H610-T626 VanDerWaalsContact CA-O 3.23Å; H610-T626 WeakPolarHBondContact CA-O 3.24Å; N611-T626 PolarHBondContact N-O 3.25Å; N611-T626 PolarHBondContact O-N 2.78Å; N611-T626 VanDerWaalsContact O-N 3.09Å; E624-T626 PolarHBondContact O-N 2.85Å; T626-F628 VanDerWaalsContact CB-CZ 3.44Å; T626-F628 WeakPolarHBondContact O-CE2 3.28Å; T626-F628 WeakPolarHBondContact OG1-CE2 3.45Å; T626-F628 WeakPolarHBondContact OG1-CZ 3.4Å; T626-K670 HydrophobicContact CG2-CD 4.09Å
627Y88.5Confident73.6Confident32 Ų3266.8 Ų66.813%0.12537%0.369CS..EExtended strand (participates in β ladder)trans-108.4136.6-172.4-69.7-115.2000110.8L521 V608 H610 P625 K661 N665L521-Y627 HydrophobicContact CD1-CD1 4.47Å; L521-Y627 HydrophobicContact CD1-CE1 4.3Å; V608-Y627 HydrophobicContact CG1-CD1 4Å; H610-Y627 HydrophobicContact CB-CD1 4.08Å; H610-Y627 HydrophobicContact CB-CD2 4.37Å; H610-Y627 HydrophobicContact CB-CE1 4.17Å; H610-Y627 HydrophobicContact CB-CE2 4.44Å; H610-Y627 HydrophobicContact CB-CG 4.18Å; P625-Y627 HydrophobicContact CB-CE2 4.23Å; P625-Y627 HydrophobicContact CG-CE2 4.11Å; P625-Y627 VanDerWaalsContact O-CD2 3.23Å; P625-Y627 WeakPolarHBondContact O-CD2 3.09Å; P625-Y627 WeakPolarHBondContact O-CE2 3.05Å; Y627-K661 HydrophobicContact CD1-CB 4.29Å; Y627-K661 HydrophobicContact CD2-CB 3.81Å; Y627-K661 HydrophobicContact CD2-CD 4.04Å; Y627-K661 HydrophobicContact CD2-CG 4.5Å; Y627-K661 HydrophobicContact CE1-CD 4.46Å; Y627-K661 HydrophobicContact CE2-CB 4.24Å; Y627-K661 HydrophobicContact CE2-CD 3.59Å; Y627-K661 HydrophobicContact CG-CB 3.85Å; Y627-N665 PolarHBondContact N-ND2 3.07Å
628F87.8Confident75.8Confident10 Ų1065.4 Ų65.44%0.04436%0.355CS..EExtended strand (participates in β ladder)trans-137.1145.2-178.4-47.6-69.7000110.6L266 V608 V609 N611 T626 A672 S675L266-F628 HydrophobicContact CD1-CD2 4.49Å; V608-F628 CarbonylContact C-O 3.39Å; V608-F628 WeakPolarHBondContact CA-O 3.45Å; V609-F628 HydrophobicContact CG2-CB 4.37Å; V609-F628 PolarHBondContact N-O 2.69Å; V609-F628 PolarHBondContact O-N 3.13Å; V609-F628 VanDerWaalsContact O-O 3.12Å; N611-F628 HydrophobicContact CB-CE2 4.38Å; T626-F628 VanDerWaalsContact CB-CZ 3.44Å; T626-F628 WeakPolarHBondContact O-CE2 3.28Å; T626-F628 WeakPolarHBondContact OG1-CE2 3.45Å; T626-F628 WeakPolarHBondContact OG1-CZ 3.4Å; F628-A672 HydrophobicContact CB-CB 4.31Å; F628-A672 HydrophobicContact CD1-CB 3.63Å; F628-A672 HydrophobicContact CE1-CB 4.24Å; F628-A672 HydrophobicContact CG-CB 4.04Å; F628-S675 VanDerWaalsContact CE1-OG 3.3Å; F628-S675 WeakPolarHBondContact CE1-OG 3.46Å; F628-S675 WeakPolarHBondContact CE2-OG 3.39Å; F628-S675 WeakPolarHBondContact CZ-OG 3.49Å
629A91.9Very high77.8Confident6 Ų662.4 Ų62.45%0.0533%0.328CS..EExtended strand (participates in β ladder)trans-96.6129.5170.600000110.5L278 Y289 I606 V662L278-A629 HydrophobicContact CB-CB 3.91Å; L278-A629 HydrophobicContact CD2-CB 3.82Å; L278-A629 PolarHBondContact N-O 3.34Å; Y289-A629 HydrophobicContact CE2-CB 3.89Å; I606-A629 HydrophobicContact CG2-CB 3.97Å; A629-V662 HydrophobicContact CB-CG1 4.22Å
630I91.9Very high79.9Confident11 Ų1157 Ų576%0.05629%0.291CS..EExtended strand (participates in β ladder)trans-122.5152.7171.366.3176.6000110.2T275 Y277 H607 V609 G632T275-I630 HydrophobicContact CG2-CB 4.4Å; T275-I630 HydrophobicContact CG2-CD1 4.33Å; T275-I630 HydrophobicContact CG2-CG2 4.11Å; Y277-I630 HydrophobicContact CD1-CG2 3.45Å; Y277-I630 VanDerWaalsContact CD1-CG2 3.45Å; Y277-I630 HydrophobicContact CE1-CG2 3.64Å; Y277-I630 HydrophobicContact CG-CG2 4.12Å; H607-I630 HydrophobicContact CB-CG1 3.91Å; H607-I630 PolarHBondContact N-O 3.37Å; H607-I630 PolarHBondContact O-N 3.06Å; V609-I630 HydrophobicContact CG1-CD1 3.86Å; V609-I630 HydrophobicContact CG1-CG1 4.23Å; V609-I630 HydrophobicContact CG2-CD1 4.24Å; V609-I630 HydrophobicContact CG2-CG1 4.39Å; V609-I630 HydrophobicContact CG2-CG2 4.19Å; I630-G632 PolarHBondContact O-N 2.76Å
631W92.8Very high82Confident67 Ų6753.9 Ų53.925%0.25427%0.269SS..EExtended strand (participates in β ladder)trans-75.3115.7168-70.9109.4000109.4K276 L278 R604 I606K276-W631 HydrophobicContact CB-CB 4.34Å; K276-W631 PolarHBondContact O-N 3.1Å; L278-W631 HydrophobicContact CD1-CH2 4.38Å; L278-W631 HydrophobicContact CD1-CZ2 3.47Å; L278-W631 VanDerWaalsContact CD1-CZ2 3.47Å; R604-W631 HydrophobicContact CB-CE3 4.49Å; R604-W631 HydrophobicContact CB-CZ3 3.9Å; I606-W631 HydrophobicContact CD1-CH2 4.21Å; I606-W631 HydrophobicContact CD1-CZ3 4.24Å; I606-W631 HydrophobicContact CG1-CE3 4.06Å; I606-W631 HydrophobicContact CG1-CH2 3.99Å; I606-W631 HydrophobicContact CG1-CZ3 3.56Å
632G90.8Very high84Confident16 Ų1645.2 Ų45.217%0.16523%0.229CC..EExtended strand (participates in β ladder)trans-90.4149.8179.100000112.8I605 I630I605-G632 PolarHBondContact O-N 3.24Å; I630-G632 PolarHBondContact O-N 2.76Å
633D91.4Very high85.3Confident85 Ų8539.1 Ų39.146%0.45520%0.202SC..  trans-90.9132168.4167.927.2000110.2K635 A636 F637D633-K635 PolarHBondContact O-N 3.25Å; D633-K635 PolarHBondContact OD1-N 3.27Å; D633-A636 HydrophobicContact CB-CB 4.21Å; D633-A636 VanDerWaalsContact O-CB 3.3Å; D633-A636 WeakPolarHBondContact O-CB 3.34Å; D633-A636 PolarHBondContact O-N 3.41Å; D633-F637 WeakPolarHBondContact O-CD2 3.36Å; D633-F637 WeakPolarHBondContact O-CE2 3.32Å
634N92.9Very high85.8Confident4 Ų434.6 Ų34.62%0.02118%0.183CC..G310 helixtrans-55.6-32.9177.5-52.776.5000112.6M509 K513 P601 G603 I605 A636M509-N634 HydrophobicContact CE-CB 4.32Å; M509-N634 HydrophobicContact CG-CB 3.96Å; M509-N634 HydrophobicContact SD-CB 3.56Å; M509-N634 VanDerWaalsContact SD-CB 3.56Å; K513-N634 WeakPolarHBondContact CE-OD1 3.38Å; K513-N634 PolarHBondContact NZ-OD1 2.91Å; P601-N634 WeakPolarHBondContact CD-O 3.37Å; P601-N634 HydrophobicContact CG-CB 4.46Å; P601-N634 PolarHBondContact O-ND2 3.42Å; G603-N634 PolarHBondContact O-ND2 3.17Å; I605-N634 HydrophobicContact CD1-CB 4.25Å; N634-A636 VanDerWaalsContact C-N 3.3Å; N634-A636 PolarHBondContact O-N 3.01Å
635K90.1Very high86.3Confident80 Ų8030.8 Ų30.835%0.34817%0.17SC..G310 helixtrans-78.7-11.6179.2-54.3-164.2-176.2-165.20113.7E506 Y600 D633 F637 N638E506-K635 WeakPolarHBondContact OE1-CE 3.47Å; E506-K635 IonicContact OE1-NZ 3.43Å; E506-K635 PolarHBondContact OE1-NZ 2.93Å; E506-K635 WeakPolarHBondContact OE2-CE 3.49Å; E506-K635 IonicContact OE2-NZ 3.19Å; E506-K635 PolarHBondContact OE2-NZ 2.85Å; Y600-K635 HydrophobicContact CD1-CG 4.19Å; Y600-K635 HydrophobicContact CE1-CB 4.29Å; Y600-K635 HydrophobicContact CE1-CD 4.36Å; Y600-K635 HydrophobicContact CE1-CG 3.85Å; D633-K635 PolarHBondContact O-N 3.25Å; D633-K635 PolarHBondContact OD1-N 3.27Å; K635-F637 VanDerWaalsContact C-N 3.25Å; K635-F637 PolarHBondContact O-N 3.34Å; K635-N638 PolarHBondContact O-ND2 2.82Å
636A87.6Confident86.7Confident36 Ų3629.1 Ų29.130%0.29816%0.159SC..G310 helixtrans-81.6-0.8-175.200000114.2M269 D633 N634M269-A636 HydrophobicContact CE-CB 3.62Å; D633-A636 HydrophobicContact CB-CB 4.21Å; D633-A636 VanDerWaalsContact O-CB 3.3Å; D633-A636 WeakPolarHBondContact O-CB 3.34Å; D633-A636 PolarHBondContact O-N 3.41Å; N634-A636 VanDerWaalsContact C-N 3.3Å; N634-A636 PolarHBondContact O-N 3.01Å
637F89.4Confident86.6Confident1 Ų129.8 Ų29.80%0.00416%0.161CC..G310 helixtrans-96.34.8179-63.7-88.4000114V520 P527 R528 P601 I605 H607 D633 K635 E639V520-F637 HydrophobicContact CB-CE1 4.18Å; V520-F637 HydrophobicContact CB-CZ 4.35Å; V520-F637 HydrophobicContact CG1-CE1 3.8Å; V520-F637 HydrophobicContact CG1-CZ 4.44Å; V520-F637 HydrophobicContact CG2-CE1 4.13Å; V520-F637 HydrophobicContact CG2-CZ 4.22Å; P527-F637 HydrophobicContact CB-CD1 4.11Å; P527-F637 VanDerWaalsContact O-CB 3.27Å; P527-F637 WeakPolarHBondContact O-CB 3.43Å; R528-F637 WeakPolarHBondContact CA-O 3.38Å; R528-F637 HydrophobicContact CG-CB 4.31Å; R528-F637 HydrophobicContact CG-CD1 4.07Å; P601-F637 HydrophobicContact CG-CB 4.45Å; P601-F637 HydrophobicContact CG-CD2 4.17Å; P601-F637 HydrophobicContact CG-CG 4.49Å; I605-F637 HydrophobicContact CD1-CD2 3.96Å; I605-F637 HydrophobicContact CD1-CE2 3.57Å; I605-F637 HydrophobicContact CD1-CZ 4.42Å; I605-F637 HydrophobicContact CG2-CE2 4.11Å; I605-F637 HydrophobicContact CG2-CZ 4.05Å; H607-F637 AromaticContact CE1-CE1 3.98Å; H607-F637 AromaticContact ND1-CZ 3.73Å; D633-F637 WeakPolarHBondContact O-CD2 3.36Å; D633-F637 WeakPolarHBondContact O-CE2 3.32Å; K635-F637 VanDerWaalsContact C-N 3.25Å; K635-F637 PolarHBondContact O-N 3.34Å; F637-E639 PolarHBondContact O-N 2.64Å; F637-E639 VanDerWaalsContact O-N 3.1Å
638N84.9Confident86.3Confident73 Ų7332 Ų3239%0.3917%0.173SC..  trans-67.7-5.1-176.8-72.4-11.6000116.4Q533 K635Q533-N638 PolarHBondContact NE2-OD1 3.2Å; K635-N638 PolarHBondContact O-ND2 2.82Å
639E85.7Confident86.2Confident64 Ų6432.2 Ų32.230%0.29917%0.174SC..SBendtrans-118.1129.8173.1-176.2166.2-132.300111.1R528 Q540 F637 I641R528-E639 WeakPolarHBondContact CD-O 3.44Å; R528-E639 PolarHBondContact NH1-O 2.96Å; R528-E639 VanDerWaalsContact NH1-O 3.17Å; Q540-E639 PolarHBondContact NE2-OE1 3.25Å; F637-E639 PolarHBondContact O-N 2.64Å; F637-E639 VanDerWaalsContact O-N 3.1Å; E639-I641 PolarHBondContact O-N 2.73Å
640V87.3Confident86.2Confident9 Ų933.1 Ų33.16%0.05518%0.177CC..  trans-71.7114.7173.4-178.50000109.3Q247 L525 R528 Q533 F537 I642Q247-V640 PolarHBondContact NE2-O 3.17Å; L525-V640 HydrophobicContact CD1-CG1 3.7Å; R528-V640 WeakPolarHBondContact O-CG2 3.08Å; Q533-V640 HydrophobicContact CB-CG2 4.42Å; F537-V640 HydrophobicContact CB-CB 4.43Å; F537-V640 HydrophobicContact CB-CG2 4.15Å; F537-V640 HydrophobicContact CD2-CG1 4.39Å; V640-I642 HydrophobicContact CG1-CD1 3.89Å
641I87.8Confident85.9Confident9 Ų935.6 Ų35.65%0.04619%0.19CC..  trans-95.8114.4-176.7-65.1-177000110.1K523 E639 S643K523-I641 HydrophobicContact CB-CG2 4.2Å; K523-I641 HydrophobicContact CD-CG2 3.96Å; K523-I641 HydrophobicContact CG-CG2 3.91Å; E639-I641 PolarHBondContact O-N 2.73Å; I641-S643 PolarHBondContact O-N 2.81Å
642I85.8Confident85.8Confident17 Ų1732.8 Ų32.89%0.08718%0.18CC..  trans-80.2120.2-175.7-47.9-53.4000111.2L240 L243 R244 Q247 F537 V640L240-I642 HydrophobicContact CB-CG2 4.33Å; L240-I642 HydrophobicContact CD2-CD1 3.74Å; L240-I642 HydrophobicContact CD2-CG1 4.25Å; L240-I642 HydrophobicContact CD2-CG2 3.97Å; L243-I642 HydrophobicContact CB-CG1 4.44Å; L243-I642 HydrophobicContact CD2-CD1 4.41Å; L243-I642 HydrophobicContact CD2-CG1 3.99Å; L243-I642 HydrophobicContact CG-CG1 4.09Å; R244-I642 HydrophobicContact CB-CB 4.03Å; R244-I642 HydrophobicContact CB-CG2 3.94Å; Q247-I642 VanDerWaalsContact OE1-N 3.14Å; F537-I642 HydrophobicContact CD2-CD1 4.24Å; F537-I642 HydrophobicContact CE2-CD1 3.83Å; V640-I642 HydrophobicContact CG1-CD1 3.89Å
643S82.5Confident85.7Confident12 Ų1235.5 Ų35.58%0.08419%0.186CC..  trans-153.2140.3179.7-167.40000109.8K523 I641 A645 M646K523-S643 VanDerWaalsContact CD-CB 3.5Å; K523-S643 WeakPolarHBondContact CD-OG 3.48Å; I641-S643 PolarHBondContact O-N 2.81Å; S643-A645 PolarHBondContact O-N 3.22Å; S643-M646 VanDerWaalsContact O-CB 3.27Å; S643-M646 WeakPolarHBondContact O-CB 3.46Å; S643-M646 WeakPolarHBondContact O-CG 3.5Å; S643-M646 PolarHBondContact O-N 2.82Å
644P72.8Confident85.7Confident22 Ų2232 Ų3214%0.14317%0.167CC..G310 helixtrans-55.1-40.7176.7-25.334.3000112R244 M646R244-P644 VanDerWaalsContact CZ-CD 3.45Å; P644-M646 VanDerWaalsContact C-N 3.26Å; P644-M646 PolarHBondContact O-N 2.85Å
645A75.3Confident85.8Confident30 Ų3031.8 Ų31.825%0.24817%0.167CC..G310 helixtrans-75-0.4178.200000115.2S643 L647 H648 E649S643-A645 PolarHBondContact O-N 3.22Å; A645-L647 PolarHBondContact O-N 2.88Å; A645-L647 VanDerWaalsContact O-N 3.14Å; A645-H648 PolarHBondContact O-N 3.43Å; A645-E649 HydrophobicContact CB-CG 4.07Å; A645-E649 WeakPolarHBondContact CB-OE1 3.48Å; A645-E649 VanDerWaalsContact O-CB 3.26Å; A645-E649 WeakPolarHBondContact O-CB 3.39Å; A645-E649 VanDerWaalsContact O-CG 3.26Å; A645-E649 WeakPolarHBondContact O-CG 3.47Å; A645-E649 PolarHBondContact O-N 2.83Å
646M82.3Confident86Confident5 Ų528.6 Ų28.63%0.02515%0.153CC..G310 helixtrans-63.5-22.9-173.673.5-166-17400114.3K523 L525 S643 P644 F921K523-M646 WeakPolarHBondContact O-CB 3.27Å; L525-M646 HydrophobicContact CB-CB 4.35Å; L525-M646 HydrophobicContact CB-CG 4.22Å; L525-M646 HydrophobicContact CD1-CE 4.33Å; L525-M646 HydrophobicContact CD1-SD 4.14Å; L525-M646 HydrophobicContact CD2-CE 4.22Å; L525-M646 PolarHBondContact N-O 3.18Å; L525-M646 VanDerWaalsContact N-O 3.13Å; S643-M646 VanDerWaalsContact O-CB 3.27Å; S643-M646 WeakPolarHBondContact O-CB 3.46Å; S643-M646 WeakPolarHBondContact O-CG 3.5Å; S643-M646 PolarHBondContact O-N 2.82Å; P644-M646 VanDerWaalsContact C-N 3.26Å; P644-M646 PolarHBondContact O-N 2.85Å; M646-F921 HydrophobicContact CE-CD1 3.58Å; M646-F921 HydrophobicContact CE-CE1 3.86Å; M646-F921 HydrophobicContact CE-CG 4.3Å
647L79.9Confident86.2Confident37 Ų3730.8 Ų30.819%0.19416%0.157CC..THydrogen-bonded Turntrans-94.4-39.7174.8-71.2162.9000111.6L525 A645 E649 H650 I917 F921L525-L647 HydrophobicContact CD2-CD2 3.65Å; L525-L647 HydrophobicContact CD2-CG 4.26Å; A645-L647 PolarHBondContact O-N 2.88Å; A645-L647 VanDerWaalsContact O-N 3.14Å; L647-E649 VanDerWaalsContact C-N 3.34Å; L647-E649 PolarHBondContact O-N 3.1Å; L647-H650 VanDerWaalsContact O-CB 3.31Å; L647-H650 WeakPolarHBondContact O-CB 3.4Å; L647-H650 PolarHBondContact O-N 3.31Å; L647-H650 VanDerWaalsContact O-N 3.11Å; L647-I917 HydrophobicContact CD1-CG2 3.9Å; L647-I917 HydrophobicContact CD2-CG2 4.42Å; L647-F921 HydrophobicContact CD1-CB 3.83Å; L647-F921 HydrophobicContact CD1-CD1 4.45Å; L647-F921 HydrophobicContact CD1-CD2 3.39Å; L647-F921 HydrophobicContact CD1-CE2 4.03Å; L647-F921 HydrophobicContact CD1-CG 3.65Å
648H81.5Confident86.4Confident78 Ų7830.8 Ų30.836%0.36116%0.157SC..G310 helixtrans-62.3-40.7174.7-177.9-91.5000112.1A645 H650 L651 Y653 V654A645-H648 PolarHBondContact O-N 3.43Å; H648-H650 PolarHBondContact O-N 2.9Å; H648-L651 WeakPolarHBondContact O-CB 3.44Å; H648-L651 PolarHBondContact O-N 2.86Å; H648-Y653 PolarHBondContact NE2-OH 3.24Å; H648-V654 VanDerWaalsContact CE1-CG2 3.44Å; H648-V654 WeakPolarHBondContact CE1-CG2 3.43Å; H648-V654 WeakPolarHBondContact O-CB 3.38Å; H648-V654 WeakPolarHBondContact O-CG2 3.27Å
649E86.6Confident86.9Confident14 Ų1427.3 Ų27.37%0.06514%0.139CC..G310 helixtrans-66.7-14.1175.7-70.5169.3-162.300113.3L521 G522 K523 H610 A645 L647L521-E649 HydrophobicContact CD2-CB 4.11Å; L521-E649 HydrophobicContact CD2-CG 4.32Å; L521-E649 WeakPolarHBondContact CD2-O 3.23Å; L521-E649 HydrophobicContact CG-CB 4.35Å; G522-E649 WeakPolarHBondContact CA-OE2 3.48Å; K523-E649 PolarHBondContact N-OE2 3.32Å; H610-E649 IonicContact CE1-OE1 2.73Å; H610-E649 PolarHBondContact CE1-OE1 3.21Å; H610-E649 VanDerWaalsContact CE1-OE1 3.31Å; H610-E649 IonicContact CE1-OE2 3.42Å; H610-E649 IonicContact NE2-OE1 3.54Å; A645-E649 HydrophobicContact CB-CG 4.07Å; A645-E649 WeakPolarHBondContact CB-OE1 3.48Å; A645-E649 VanDerWaalsContact O-CB 3.26Å; A645-E649 WeakPolarHBondContact O-CB 3.39Å; A645-E649 VanDerWaalsContact O-CG 3.26Å; A645-E649 WeakPolarHBondContact O-CG 3.47Å; A645-E649 PolarHBondContact O-N 2.83Å; L647-E649 VanDerWaalsContact C-N 3.34Å; L647-E649 PolarHBondContact O-N 3.1Å
650H90.7Very high87.3Confident25 Ų2527.5 Ų27.512%0.11614%0.142CC..G310 helixtrans-84.8-12.5171-170.862000113.5H471 S472 D524 V526 L647 H648H471-H650 AromaticContact CE1-CE1 3.83Å; H471-H650 AromaticContact CE1-NE2 3.72Å; H471-H650 PolarHBondContact CE1-O 3.08Å; H471-H650 PolarHBondContact NE2-O 3.25Å; S472-H650 WeakPolarHBondContact CB-NE2 3.37Å; S472-H650 PolarHBondContact OG-CE1 3.48Å; S472-H650 PolarHBondContact OG-NE2 2.67Å; D524-H650 VanDerWaalsContact CG-ND1 3.27Å; D524-H650 WeakPolarHBondContact OD1-CB 3.48Å; D524-H650 IonicContact OD1-CG 2.72Å; D524-H650 IonicContact OD1-ND1 3.19Å; D524-H650 PolarHBondContact OD1-ND1 3.31Å; D524-H650 IonicContact OD2-CE1 3.89Å; D524-H650 IonicContact OD2-CG 2.72Å; D524-H650 IonicContact OD2-ND1 2.62Å; D524-H650 PolarHBondContact OD2-ND1 2.88Å; V526-H650 VanDerWaalsContact CB-CE1 3.46Å; V526-H650 WeakPolarHBondContact CB-CE1 3.49Å; L647-H650 VanDerWaalsContact O-CB 3.31Å; L647-H650 WeakPolarHBondContact O-CB 3.4Å; L647-H650 PolarHBondContact O-N 3.31Å; L647-H650 VanDerWaalsContact O-N 3.11Å; H648-H650 PolarHBondContact O-N 2.9Å
651L86.5Confident87.5Confident63 Ų6329.5 Ų29.533%0.3315%0.15SC..SBendtrans-71.9132.7-176.2-62.4171.5000110.1H648 Y653 V654 V655H648-L651 WeakPolarHBondContact O-CB 3.44Å; H648-L651 PolarHBondContact O-N 2.86Å; L651-Y653 HydrophobicContact CB-CD1 3.87Å; L651-Y653 HydrophobicContact CB-CE1 3.58Å; L651-Y653 HydrophobicContact CD1-CE1 3.72Å; L651-Y653 HydrophobicContact CG-CE1 4.22Å; L651-Y653 PolarHBondContact O-N 3.3Å; L651-Y653 VanDerWaalsContact O-N 3.09Å; L651-V654 HydrophobicContact CB-CB 4.44Å; L651-V654 HydrophobicContact CB-CG2 3.91Å; L651-V654 WeakPolarHBondContact O-CA 3.33Å; L651-V654 WeakPolarHBondContact O-CB 3.37Å; L651-V654 PolarHBondContact O-N 2.83Å; L651-V655 PolarHBondContact O-N 2.88Å
652P90.9Very high87.7Confident8 Ų829.3 Ų29.35%0.05215%0.149CC..Hα-helixtrans-64.8-24.8-167.923-33.8000113.6M296 L300 Y303 M307 M656M296-P652 HydrophobicContact CE-CB 3.7Å; M296-P652 WeakPolarHBondContact CE-O 3.15Å; L300-P652 HydrophobicContact CD1-CB 4.03Å; L300-P652 HydrophobicContact CD1-CG 4.17Å; Y303-P652 HydrophobicContact CD2-CG 4.24Å; Y303-P652 HydrophobicContact CE2-CB 4.22Å; Y303-P652 HydrophobicContact CE2-CG 3.8Å; M307-P652 HydrophobicContact CE-CG 4.06Å; M307-P652 HydrophobicContact SD-CG 4.47Å; P652-M656 PolarHBondContact O-N 3.49Å; P652-M656 VanDerWaalsContact O-N 3.16Å
653Y88.6Confident87.9Confident74 Ų7429.8 Ų29.829%0.2915%0.152SC..Hα-helixtrans-72.2-32.4172.173.6-88.2000112.6M307 H648 L651 M656 E657M307-Y653 HydrophobicContact CE-CD1 3.97Å; H648-Y653 PolarHBondContact NE2-OH 3.24Å; L651-Y653 HydrophobicContact CB-CD1 3.87Å; L651-Y653 HydrophobicContact CB-CE1 3.58Å; L651-Y653 HydrophobicContact CD1-CE1 3.72Å; L651-Y653 HydrophobicContact CG-CE1 4.22Å; L651-Y653 PolarHBondContact O-N 3.3Å; L651-Y653 VanDerWaalsContact O-N 3.09Å; Y653-M656 PolarHBondContact O-N 2.87Å; Y653-E657 WeakPolarHBondContact O-CB 3.25Å; Y653-E657 PolarHBondContact O-N 3.31Å
654V91.2Very high88.3Confident10 Ų1033 Ų336%0.06117%0.166CC..Hα-helixtrans-75.7-37.1177.9-172.80000110.5L521 H648 L651 M656 E657 G658L521-V654 HydrophobicContact CD2-CG1 3.84Å; L521-V654 WeakPolarHBondContact CD2-O 3.31Å; H648-V654 VanDerWaalsContact CE1-CG2 3.44Å; H648-V654 WeakPolarHBondContact CE1-CG2 3.43Å; H648-V654 WeakPolarHBondContact O-CB 3.38Å; H648-V654 WeakPolarHBondContact O-CG2 3.27Å; L651-V654 HydrophobicContact CB-CB 4.44Å; L651-V654 HydrophobicContact CB-CG2 3.91Å; L651-V654 WeakPolarHBondContact O-CA 3.33Å; L651-V654 WeakPolarHBondContact O-CB 3.37Å; L651-V654 PolarHBondContact O-N 2.83Å; V654-M656 VanDerWaalsContact C-N 3.34Å; V654-E657 PolarHBondContact O-N 3.47Å; V654-G658 PolarHBondContact O-N 3.32Å
655V94.4Very high88.8Confident1 Ų132.3 Ų32.31%0.00616%0.161CC..Hα-helixtrans-58.9-45.2169.1176.60000110.8M296 Y497 V519 L521 L651 G658 L659M296-V655 HydrophobicContact CE-CB 3.99Å; M296-V655 HydrophobicContact CE-CG1 4Å; M296-V655 HydrophobicContact SD-CG1 4.46Å; Y497-V655 HydrophobicContact CD1-CG1 4.48Å; V519-V655 HydrophobicContact CG1-CG1 4.46Å; L521-V655 HydrophobicContact CB-CG2 4.32Å; L651-V655 PolarHBondContact O-N 2.88Å; V655-G658 PolarHBondContact O-N 2.79Å; V655-L659 WeakPolarHBondContact O-CG 3.4Å; V655-L659 PolarHBondContact O-N 3.31Å; V655-L659 VanDerWaalsContact O-N 3.07Å
656M93.7Very high89.3Confident12 Ų1234.6 Ų34.66%0.05916%0.163CC..Hα-helixtrans-62.7-44.2173.7175.959.190.200112.7M296 L297 P652 Y653 V654 G658 L659 N660M296-M656 HydrophobicContact CB-CE 3.61Å; M296-M656 HydrophobicContact CB-SD 4.38Å; M296-M656 HydrophobicContact CG-CB 4.15Å; M296-M656 HydrophobicContact CG-CE 3.71Å; M296-M656 HydrophobicContact CG-SD 4.28Å; L297-M656 HydrophobicContact CB-CE 4.42Å; L297-M656 HydrophobicContact CD2-CE 3.49Å; L297-M656 VanDerWaalsContact CD2-CE 3.49Å; L297-M656 HydrophobicContact CG-CE 3.62Å; P652-M656 PolarHBondContact O-N 3.49Å; P652-M656 VanDerWaalsContact O-N 3.16Å; Y653-M656 PolarHBondContact O-N 2.87Å; V654-M656 VanDerWaalsContact C-N 3.34Å; M656-G658 PolarHBondContact O-N 2.84Å; M656-L659 PolarHBondContact O-N 3.22Å; M656-N660 PolarHBondContact O-N 2.94Å; M656-N660 PolarHBondContact O-ND2 2.91Å; M656-N660 PolarHBondContact SD-ND2 2.95Å; M656-N660 VanDerWaalsContact SD-ND2 3.35Å
657E92.3Very high89.4Confident82 Ų8240.5 Ų40.538%0.38320%0.195SC..Hα-helixtrans-61.9-42.8177.4-166.7-170.4136.300111.7Y653 V654 L659 N660 K661Y653-E657 WeakPolarHBondContact O-CB 3.25Å; Y653-E657 PolarHBondContact O-N 3.31Å; V654-E657 PolarHBondContact O-N 3.47Å; E657-L659 PolarHBondContact O-N 2.74Å; E657-N660 PolarHBondContact O-N 3.08Å; E657-K661 HydrophobicContact CG-CD 4.27Å; E657-K661 WeakPolarHBondContact O-CB 3.36Å; E657-K661 WeakPolarHBondContact O-CG 3.32Å; E657-K661 PolarHBondContact O-N 3.11Å; E657-K661 VanDerWaalsContact OE1-CE 3.26Å; E657-K661 WeakPolarHBondContact OE1-CE 3.4Å; E657-K661 IonicContact OE1-NZ 3.36Å; E657-K661 PolarHBondContact OE1-NZ 2.8Å
658G93.1Very high89.4Confident1 Ų143.4 Ų43.41%0.0121%0.206CC..Hα-helixtrans-61.7-41.3175.800000113.3V654 V655 M656 K661 V662V654-G658 PolarHBondContact O-N 3.32Å; V655-G658 PolarHBondContact O-N 2.79Å; M656-G658 PolarHBondContact O-N 2.84Å; G658-K661 PolarHBondContact O-N 2.9Å; G658-V662 PolarHBondContact O-N 2.74Å
659L95.2Very high88.9Confident1 Ų141.7 Ų41.71%0.00521%0.21CC..Hα-helixtrans-61-47173.4-74170.1000111.7Y289 V292 M296 Y497 V519 V608 V655 M656 E657 K661 V662 L663Y289-L659 HydrophobicContact CE2-CD2 4.07Å; Y289-L659 WeakPolarHBondContact OH-CD2 3.27Å; V292-L659 HydrophobicContact CG1-CD1 4.43Å; V292-L659 HydrophobicContact CG1-CD2 4.05Å; M296-L659 HydrophobicContact CB-CD1 4.13Å; M296-L659 HydrophobicContact CG-CD1 4.17Å; Y497-L659 HydrophobicContact CD1-CD1 4.45Å; Y497-L659 HydrophobicContact CE1-CD1 4.18Å; V519-L659 HydrophobicContact CG1-CD2 4.06Å; V608-L659 HydrophobicContact CG2-CD2 4.01Å; V655-L659 WeakPolarHBondContact O-CG 3.4Å; V655-L659 PolarHBondContact O-N 3.31Å; V655-L659 VanDerWaalsContact O-N 3.07Å; M656-L659 PolarHBondContact O-N 3.22Å; E657-L659 PolarHBondContact O-N 2.74Å; L659-K661 PolarHBondContact O-N 3.13Å; L659-V662 PolarHBondContact O-N 3.24Å; L659-L663 PolarHBondContact O-N 3.18Å
660N94Very high88.1Confident67 Ų6745.1 Ų45.136%0.35822%0.224SC..Hα-helixtrans-65.7-38.7178.5-71.6-48000112.3M656 E657 V662 L663 E664M656-N660 PolarHBondContact O-N 2.94Å; M656-N660 PolarHBondContact O-ND2 2.91Å; M656-N660 PolarHBondContact SD-ND2 2.95Å; M656-N660 VanDerWaalsContact SD-ND2 3.35Å; E657-N660 PolarHBondContact O-N 3.08Å; N660-V662 VanDerWaalsContact C-N 3.25Å; N660-V662 PolarHBondContact O-N 3.21Å; N660-L663 WeakPolarHBondContact O-CB 3.48Å; N660-L663 PolarHBondContact O-N 2.92Å; N660-E664 PolarHBondContact O-N 3.41Å
661K92.3Very high86.7Confident51 Ų5145.7 Ų45.722%0.22223%0.23CC..Hα-helixtrans-63.1-25.9175.9-78.9177.7169.8174.10113.6Y627 E657 G658 L659 N665Y627-K661 HydrophobicContact CD1-CB 4.29Å; Y627-K661 HydrophobicContact CD2-CB 3.81Å; Y627-K661 HydrophobicContact CD2-CD 4.04Å; Y627-K661 HydrophobicContact CD2-CG 4.5Å; Y627-K661 HydrophobicContact CE1-CD 4.46Å; Y627-K661 HydrophobicContact CE2-CB 4.24Å; Y627-K661 HydrophobicContact CE2-CD 3.59Å; Y627-K661 HydrophobicContact CG-CB 3.85Å; E657-K661 HydrophobicContact CG-CD 4.27Å; E657-K661 WeakPolarHBondContact O-CB 3.36Å; E657-K661 WeakPolarHBondContact O-CG 3.32Å; E657-K661 PolarHBondContact O-N 3.11Å; E657-K661 VanDerWaalsContact OE1-CE 3.26Å; E657-K661 WeakPolarHBondContact OE1-CE 3.4Å; E657-K661 IonicContact OE1-NZ 3.36Å; E657-K661 PolarHBondContact OE1-NZ 2.8Å; G658-K661 PolarHBondContact O-N 2.9Å; L659-K661 PolarHBondContact O-N 3.13Å; K661-N665 WeakPolarHBondContact O-CB 3.21Å; K661-N665 PolarHBondContact O-N 3.11Å; K661-N665 PolarHBondContact O-ND2 2.93Å
662V91.9Very high85.4Confident6 Ų643.6 Ų43.64%0.03622%0.221CC..Hα-helixtrans-69-44.5170174.50000111.1L280 Y289 V608 A629 G658 L659 N660 N665 Y666L280-V662 HydrophobicContact CD1-CG1 3.75Å; Y289-V662 HydrophobicContact CE1-CB 4.04Å; Y289-V662 HydrophobicContact CE1-CG1 3.92Å; Y289-V662 VanDerWaalsContact OH-CB 3.28Å; Y289-V662 WeakPolarHBondContact OH-CB 3.43Å; Y289-V662 WeakPolarHBondContact OH-CG2 3.06Å; V608-V662 HydrophobicContact CG1-CG2 3.72Å; V608-V662 HydrophobicContact CG2-CG2 4.47Å; A629-V662 HydrophobicContact CB-CG1 4.22Å; G658-V662 PolarHBondContact O-N 2.74Å; L659-V662 PolarHBondContact O-N 3.24Å; N660-V662 VanDerWaalsContact C-N 3.25Å; N660-V662 PolarHBondContact O-N 3.21Å; V662-N665 PolarHBondContact O-N 2.88Å; V662-Y666 PolarHBondContact O-N 3.38Å
663L91.1Very high83.7Confident27 Ų2749.4 Ų49.414%0.14125%0.251CS..Hα-helixtrans-63-41.3175.5-71.6176.5000111.8M286 Y289 L659 N660 Y666 N667M286-L663 HydrophobicContact CE-CD2 4.29Å; M286-L663 HydrophobicContact SD-CD2 4.06Å; Y289-L663 HydrophobicContact CD1-CD2 3.85Å; Y289-L663 HydrophobicContact CD1-CG 4.11Å; Y289-L663 HydrophobicContact CE1-CD2 4.23Å; Y289-L663 HydrophobicContact CE1-CG 4.04Å; L659-L663 PolarHBondContact O-N 3.18Å; N660-L663 WeakPolarHBondContact O-CB 3.48Å; N660-L663 PolarHBondContact O-N 2.92Å; L663-Y666 PolarHBondContact O-N 3.09Å; L663-N667 WeakPolarHBondContact O-CB 3.29Å; L663-N667 PolarHBondContact O-N 3.22Å; L663-N667 PolarHBondContact O-ND2 3.37Å
664E89.4Confident82.2Confident80 Ų8051.2 Ų51.237%0.37427%0.265SS..Hα-helixtrans-61.5-48.1173.5-76.8-174.2-138.500112.6N660 Y666 N667 K668N660-E664 PolarHBondContact O-N 3.41Å; E664-Y666 VanDerWaalsContact C-N 3.28Å; E664-Y666 PolarHBondContact O-N 2.99Å; E664-N667 PolarHBondContact O-N 3.03Å; E664-N667 VanDerWaalsContact O-N 3.17Å; E664-K668 HydrophobicContact CB-CD 4.41Å; E664-K668 VanDerWaalsContact O-CB 3.27Å; E664-K668 WeakPolarHBondContact O-CB 3.25Å; E664-K668 WeakPolarHBondContact O-CG 3.36Å; E664-K668 PolarHBondContact O-N 2.8Å; E664-K668 IonicContact OE2-NZ 3.01Å; E664-K668 PolarHBondContact OE2-NZ 2.84Å
665N85.1Confident80.5Confident7 Ų751.8 Ų51.84%0.03727%0.269CS..Hα-helixtrans-62.9-36.7179.8-81-62.5000111.5Y627 K661 V662 K668 G669 K670Y627-N665 PolarHBondContact N-ND2 3.07Å; K661-N665 WeakPolarHBondContact O-CB 3.21Å; K661-N665 PolarHBondContact O-N 3.11Å; K661-N665 PolarHBondContact O-ND2 2.93Å; V662-N665 PolarHBondContact O-N 2.88Å; N665-K668 PolarHBondContact O-N 3.4Å; N665-G669 PolarHBondContact O-N 2.92Å; N665-K670 HydrophobicContact CB-CB 4.28Å; N665-K670 WeakPolarHBondContact O-CA 3.44Å; N665-K670 WeakPolarHBondContact O-CB 3.38Å; N665-K670 PolarHBondContact O-N 3.05Å; N665-K670 WeakPolarHBondContact OD1-CD 3.37Å
666Y84.3Confident78.4Confident78 Ų7852.8 Ų52.831%0.30628%0.278SS..Hα-helixtrans-61.1-49.8170.5-179.6-96.2000112.1L280 K281 M286 V662 L663 E664 K668 G669L280-Y666 HydrophobicContact CB-CD2 3.48Å; L280-Y666 VanDerWaalsContact CB-CD2 3.48Å; L280-Y666 HydrophobicContact CB-CE2 3.58Å; L280-Y666 HydrophobicContact CB-CG 4.08Å; L280-Y666 HydrophobicContact CD1-CD2 4.18Å; L280-Y666 HydrophobicContact CD1-CG 4.23Å; L280-Y666 HydrophobicContact CG-CD2 4.49Å; L280-Y666 PolarHBondContact O-OH 3.32Å; K281-Y666 HydrophobicContact CG-CE2 4.19Å; M286-Y666 HydrophobicContact CE-CD1 3.82Å; M286-Y666 HydrophobicContact CE-CE1 3.72Å; M286-Y666 HydrophobicContact CE-CG 4.39Å; V662-Y666 PolarHBondContact O-N 3.38Å; L663-Y666 PolarHBondContact O-N 3.09Å; E664-Y666 VanDerWaalsContact C-N 3.28Å; E664-Y666 PolarHBondContact O-N 2.99Å; Y666-K668 VanDerWaalsContact C-N 3.33Å; Y666-K668 PolarHBondContact O-N 3.27Å; Y666-G669 PolarHBondContact O-N 2.88Å
667N83.9Confident76.5Confident128 Ų12854.4 Ų54.468%0.68429%0.293SS*.Hα-helixtrans-64.8-34.7178.7-66.5-21000112.7L663 E664 G669L663-N667 WeakPolarHBondContact O-CB 3.29Å; L663-N667 PolarHBondContact O-N 3.22Å; L663-N667 PolarHBondContact O-ND2 3.37Å; E664-N667 PolarHBondContact O-N 3.03Å; E664-N667 VanDerWaalsContact O-N 3.17Å; N667-G669 PolarHBondContact O-N 3.21Å
668K81.1Confident74.6Confident99 Ų9956.2 Ų56.243%0.4330%0.3SS..THydrogen-bonded Turntrans-73.33.4173.3-69.4165.7173.6169.90112.5E624 E664 N665 Y666 K670E624-K668 IonicContact OE2-NZ 2.64Å; E624-K668 PolarHBondContact OE2-NZ 3.06Å; E664-K668 HydrophobicContact CB-CD 4.41Å; E664-K668 VanDerWaalsContact O-CB 3.27Å; E664-K668 WeakPolarHBondContact O-CB 3.25Å; E664-K668 WeakPolarHBondContact O-CG 3.36Å; E664-K668 PolarHBondContact O-N 2.8Å; E664-K668 IonicContact OE2-NZ 3.01Å; E664-K668 PolarHBondContact OE2-NZ 2.84Å; N665-K668 PolarHBondContact O-N 3.4Å; Y666-K668 VanDerWaalsContact C-N 3.33Å; Y666-K668 PolarHBondContact O-N 3.27Å; K668-K670 HydrophobicContact CB-CG 4.41Å; K668-K670 PolarHBondContact O-N 3.09Å
669G71.5Confident72.5Confident42 Ų4259.1 Ų59.143%0.43332%0.317SS..THydrogen-bonded Turntrans72.11.2-18000000115.3N665 Y666 N667 T671N665-G669 PolarHBondContact O-N 2.92Å; Y666-G669 PolarHBondContact O-N 2.88Å; N667-G669 PolarHBondContact O-N 3.21Å; G669-T671 PolarHBondContact O-N 3.08Å
670K68Low70.1Confident86 Ų8664.3 Ų64.337%0.37434%0.343SS..  trans-75.465.4-180-66-178.6174.9-177.40110.6T626 N665 K668T626-K670 HydrophobicContact CG2-CD 4.09Å; N665-K670 HydrophobicContact CB-CB 4.28Å; N665-K670 WeakPolarHBondContact O-CA 3.44Å; N665-K670 WeakPolarHBondContact O-CB 3.38Å; N665-K670 PolarHBondContact O-N 3.05Å; N665-K670 WeakPolarHBondContact OD1-CD 3.37Å; K668-K670 HydrophobicContact CB-CG 4.41Å; K668-K670 PolarHBondContact O-N 3.09Å
671T63.1Low67.5Low37 Ų3766.6 Ų66.623%0.22736%0.359CS..  trans-66.5149.1179.969.20000111.9G669 L673 L674 S675G669-T671 PolarHBondContact O-N 3.08Å; T671-L673 PolarHBondContact O-N 3.14Å; T671-L673 VanDerWaalsContact O-N 3.12Å; T671-L674 PolarHBondContact O-N 2.7Å; T671-S675 PolarHBondContact O-N 3Å
672A57.7Low64.8Low18 Ų1868.2 Ų68.215%0.14938%0.377CS..Hα-helixtrans-58.8-25.8-179.200000114.1Y277 F628 S675 A676Y277-A672 HydrophobicContact CD1-CB 3.4Å; Y277-A672 HydrophobicContact CE1-CB 3.64Å; Y277-A672 HydrophobicContact CG-CB 4.02Å; F628-A672 HydrophobicContact CB-CB 4.31Å; F628-A672 HydrophobicContact CD1-CB 3.63Å; F628-A672 HydrophobicContact CE1-CB 4.24Å; F628-A672 HydrophobicContact CG-CB 4.04Å; A672-S675 WeakPolarHBondContact CA-OG 3.25Å; A672-S675 PolarHBondContact O-OG 3.33Å; A672-S675 VanDerWaalsContact O-OG 3.06Å; A672-A676 WeakPolarHBondContact O-CB 3.15Å; A672-A676 PolarHBondContact O-N 2.96Å
673L56.1Low62.2Low130 Ų13074.1 Ų74.168%0.68142%0.415SS*.Hα-helixtrans-72.4-35.7174.3-78165.5000112.6T671 A677T671-L673 PolarHBondContact O-N 3.14Å; T671-L673 VanDerWaalsContact O-N 3.12Å; L673-A677 VanDerWaalsContact O-CB 3.27Å; L673-A677 WeakPolarHBondContact O-CB 3.31Å; L673-A677 PolarHBondContact O-N 3.24Å
674L56.1Low59.2Low113 Ų11379.1 Ų79.159%0.59245%0.447SS*.Hα-helixtrans-74.2-35.9177.4-69.6171.4000111.7T671 A677 K678T671-L674 PolarHBondContact O-N 2.7Å; L674-A677 PolarHBondContact O-N 2.87Å; L674-K678 PolarHBondContact O-N 3.11Å
675S55.8Low56.6Low21 Ų2184.8 Ų84.815%0.14747%0.473CS..Hα-helixtrans-72.9-3917357.50000112.4F628 T671 A672 A677 K678 V679F628-S675 VanDerWaalsContact CE1-OG 3.3Å; F628-S675 WeakPolarHBondContact CE1-OG 3.46Å; F628-S675 WeakPolarHBondContact CE2-OG 3.39Å; F628-S675 WeakPolarHBondContact CZ-OG 3.49Å; T671-S675 PolarHBondContact O-N 3Å; A672-S675 WeakPolarHBondContact CA-OG 3.25Å; A672-S675 PolarHBondContact O-OG 3.33Å; A672-S675 VanDerWaalsContact O-OG 3.06Å; S675-A677 VanDerWaalsContact C-N 3.32Å; S675-A677 PolarHBondContact O-N 3.04Å; S675-K678 PolarHBondContact O-N 3.19Å; S675-V679 WeakPolarHBondContact O-CG2 3.45Å; S675-V679 PolarHBondContact O-N 3.21Å
676A51.7Low54Low23 Ų2389.9 Ų89.919%0.1950%0.504CS..Hα-helixtrans-60.6-41.8169.900000111.1A672 V679 M680A672-A676 WeakPolarHBondContact O-CB 3.15Å; A672-A676 PolarHBondContact O-N 2.96Å; A676-V679 CarbonylContact O-C 3.59Å; A676-V679 PolarHBondContact O-N 3.24Å; A676-V679 VanDerWaalsContact O-N 3.15Å; A676-M680 VanDerWaalsContact O-CG 3.31Å; A676-M680 WeakPolarHBondContact O-CG 3.09Å; A676-M680 PolarHBondContact O-N 2.83Å
677A52Low51.3Low45 Ų4593.7 Ų93.737%0.37253%0.53SS..Hα-helixtrans-61.8-43.2172.700000112.6L673 L674 S675 V679 M680 V681L673-A677 VanDerWaalsContact O-CB 3.27Å; L673-A677 WeakPolarHBondContact O-CB 3.31Å; L673-A677 PolarHBondContact O-N 3.24Å; L674-A677 PolarHBondContact O-N 2.87Å; S675-A677 VanDerWaalsContact C-N 3.32Å; S675-A677 PolarHBondContact O-N 3.04Å; A677-V679 PolarHBondContact O-N 2.99Å; A677-M680 CarbonylContact O-C 3.56Å; A677-M680 PolarHBondContact O-N 3.42Å; A677-M680 VanDerWaalsContact O-N 3.13Å; A677-V681 WeakPolarHBondContact O-CB 3.34Å; A677-V681 WeakPolarHBondContact O-CG2 3.3Å; A677-V681 PolarHBondContact O-N 2.98Å
678K53.5Low48.7Very low120 Ų12094.8 Ų94.852%0.52254%0.535SS..Hα-helixtrans-59.4-30.2173.7-168.3-180-178.6-177.10112.4E623 L674 S675E623-K678 IonicContact OE1-NZ 2.77Å; E623-K678 PolarHBondContact OE1-NZ 3.21Å; E623-K678 IonicContact OE2-NZ 2.89Å; E623-K678 PolarHBondContact OE2-NZ 3.38Å; L674-K678 PolarHBondContact O-N 3.11Å; S675-K678 PolarHBondContact O-N 3.19Å
679V49.7Very low46.1Very low62 Ų6294.8 Ų94.838%0.37654%0.543SS..Hα-helixtrans-82.3-31.7175.1172.80000112.7A264 S675 A676 A677 V681A264-V679 HydrophobicContact CB-CG1 4.03Å; S675-V679 WeakPolarHBondContact O-CG2 3.45Å; S675-V679 PolarHBondContact O-N 3.21Å; A676-V679 CarbonylContact O-C 3.59Å; A676-V679 PolarHBondContact O-N 3.24Å; A676-V679 VanDerWaalsContact O-N 3.15Å; A677-V679 PolarHBondContact O-N 2.99Å; V679-V681 VanDerWaalsContact C-N 3.34Å
680M43Very low44.1Very low110 Ų11098.4 Ų98.454%0.54256%0.559SS.*Hα-helixtrans-81.4-10.3175.8-67.8177.275.400113.6L263 A676 A677L263-M680 HydrophobicContact CD1-CE 4.16Å; L263-M680 HydrophobicContact CD1-SD 3.91Å; L263-M680 HydrophobicContact CD2-CE 4.3Å; A676-M680 VanDerWaalsContact O-CG 3.31Å; A676-M680 WeakPolarHBondContact O-CG 3.09Å; A676-M680 PolarHBondContact O-N 2.83Å; A677-M680 CarbonylContact O-C 3.56Å; A677-M680 PolarHBondContact O-N 3.42Å; A677-M680 VanDerWaalsContact O-N 3.13Å
681V41.2Very low42.4Very low115 Ų115102.9 Ų102.970%0.69758%0.582SS**SBendtrans-128.666.4-175.6-171.60000110.9A677 V679A677-V681 WeakPolarHBondContact O-CB 3.34Å; A677-V681 WeakPolarHBondContact O-CG2 3.3Å; A677-V681 PolarHBondContact O-N 2.98Å; V679-V681 VanDerWaalsContact C-N 3.34Å
682S34Very low40.9Very low86 Ų86108.7 Ų108.760%0.60161%0.61SS**  trans174.2152.5148.843.30000109.9
683P37.6Very low39.6Very low130 Ų130114.8 Ų114.884%0.84464%0.639SS**SBendcis-107.8102.6636.4-25.4000113.6
684T29.5Very low38.3Very low131 Ų131118.4 Ų118.480%0.80465%0.65SS**SBendtrans-120.2138.8138.837.70000107V686T684-V686 PolarHBondContact O-N 3.1Å
685E34.5Very low37.1Very low199 Ų199121.5 Ų121.593%0.9366%0.661SS**  trans-73113-168.5-63.1173.5142.600111.6
686V29.6Very low35.8Very low114 Ų114129.2 Ų129.269%0.69170%0.695SS**  trans-142.3101158.5-1700000108.2T684 L688T684-V686 PolarHBondContact O-N 3.1Å; V686-L688 HydrophobicContact CG1-CD1 4.43Å; V686-L688 HydrophobicContact CG1-CG 4.19Å; V686-L688 PolarHBondContact O-N 2.96Å
687D28.2Very low34.6Very low159 Ų159136.7 Ų136.785%0.8573%0.726SS**  trans-65.2118.1171-87.4-45000110.1
688L28.9Very low33.7Very low150 Ų150140.2 Ų140.279%0.78575%0.745SS**  trans-123.876.7171.5-77.1170.1000109.1V686V686-L688 HydrophobicContact CG1-CD1 4.43Å; V686-L688 HydrophobicContact CG1-CG 4.19Å; V686-L688 PolarHBondContact O-N 2.96Å
689T26.6Very low32.3Very low99 Ų99141.9 Ų141.961%0.60776%0.759SS**  trans-64.2123172.342.90000110E691T689-E691 PolarHBondContact O-N 3.22Å; T689-E691 VanDerWaalsContact O-N 3.08Å
690P29.8Very low32.1Very low118 Ų118143.7 Ų143.777%0.76677%0.772SS**G310 helixtrans-79.29.6-166.431.2-36.8000115.2
691E31.9Very low31.3Very low181 Ų181145.3 Ų145.385%0.84679%0.788SS**G310 helixtrans-92.6-6.7-171-60.8-161139.400115.2T689T689-E691 PolarHBondContact O-N 3.22Å; T689-E691 VanDerWaalsContact O-N 3.08Å
692L32.3Very low30.6Very low158 Ų158143.3 Ų143.383%0.82779%0.791SS**G310 helixtrans-996.4-178.7-75172.1000115.1
693I29.7Very low30.7Very low147 Ų147145.2 Ų145.275%0.75480%0.801SS**  trans-113.953.5-179.1-42-178.3000111.4
694F29.6Very low30.6Very low205 Ų205144.3 Ų144.390%0.89980%0.795SS**SBendtrans-144.134.5169.2-116.4-68000115.8
695Q31.2Very low30.4Very low179 Ų179146 Ų14684%0.83680%0.796SS**SBendtrans-145.3151.8161.4-113.8175.921.200112.4
696Q27.9Very low30.7Very low182 Ų182141.4 Ų141.485%0.8578%0.783SS**  trans71.293.7173.3-54-177.214.400117.9
697Q26.3Very low30.5Very low181 Ų181141 Ų14185%0.84679%0.792SS**  trans-106.4147.3134.1-84-169.2-9.900106.9
698P32.9Very low30.3Very low119 Ų119137.2 Ų137.277%0.77379%0.791SS**  -149.5131.281.136-15.6000117.9
699L23.5Very low30.2Very low154 Ų154138.6 Ų138.681%0.80680%0.798SS**  trans67.3176.9135.8-11774.6000118.4
700P45.8Very low30.1Very low101 Ų101138.8 Ų138.866%0.65681%0.809SS**  -131.4173.3-114.643.9-27.6000116.2
701T27.3Very low30.1Very low144 Ų144140.3 Ų140.388%0.88381%0.81SS**  trans173.3156.4133.526.40000113.8
702G26.2Very low29.7Very low73 Ų73140.4 Ų140.475%0.75381%0.811SS**  trans82.6113.3136.600000120.8
703P34.9Very low29.6Very low125 Ų125140.2 Ų140.281%0.81281%0.81SS**  trans-97.1-173.2156.642.6-35.9000110.6
704P36.4Very low30Very low111 Ų111138.3 Ų138.372%0.72181%0.807SS**  cis-134.9-177.3-1.844.2-27.1000115.9
705M24Very low29.9Very low166 Ų166134.5 Ų134.582%0.81880%0.801SS**  trans7.9164.5134.5-57-65.3-8700121.4
706P41.1Very low29.8Very low103 Ų103130 Ų13067%0.66979%0.794SS**  cis-144.2-179.4-33.540.2-22.5000115.2
707A26.2Very low29.6Very low106 Ų106128.9 Ų128.988%0.87679%0.794SS**  trans58.1147.4146.900000122.2
708G23.7Very low29.7Very low80 Ų80128.8 Ų128.883%0.82579%0.793SS**  trans155.5112.1164.300000115.4
709L27.7Very low29.4Very low179 Ų179134.7 Ų134.794%0.93780%0.8SS**  trans-74.3143.9174.3-78.9148.7000112.6
710A23.4Very low29.5Very low102 Ų102134.3 Ų134.384%0.84380%0.799SS**  trans-148155.5153.300000109.5
711L29.3Very low28.7Very low151 Ų151134.5 Ų134.579%0.79180%0.803SS**  trans-117148.2-168.5-143.380.8000111.3
712E24.2Very low28.6Very low183 Ų183133.1 Ų133.186%0.85580%0.799SS**  172.8175.8114.4-85.7-156145.800112.1
713L30.6Very low28.8Very low154 Ų154136.4 Ų136.481%0.80680%0.804SS**  trans-101.9-178.4-165.9-110.679.6000112.4
714P38.7Very low28.4Very low107 Ų107141.3 Ų141.370%0.69581%0.806SS**  cis-138.9169.618.242.5-23.4000119
715T27Very low28Very low124 Ų124141.6 Ų141.676%0.76181%0.811SS**  trans11.9147.1147.365.10000121
716A28.3Very low28.3Very low84 Ų84142.4 Ų142.469%0.69481%0.81SS**  cis-166.1175.239.200000116.5
717D24.4Very low27.6Very low159 Ų159142.1 Ų142.185%0.8581%0.81SS**  trans80125.8151.6-70.6-11000125.5
718H27.9Very low27.8Very low179 Ų179144.5 Ų144.583%0.82980%0.803SS**  trans-75173.2165.3-64.4-79.7000111.5
719R25.9Very low28.1Very low243 Ų243146.1 Ų146.192%0.91780%0.802SS**  -177.617661.4-135.8164.6-168.2173.43.1113
720N26.4Very low28.2Very low147 Ų147144.4 Ų144.479%0.78679%0.789SS**  trans-100.8154.9-162.8-66-9.9000116.9
721S28.9Very low28.3Very low105 Ų105148.4 Ų148.473%0.73479%0.792SS**  trans70.7130.513565.90000123
722S26.4Very low28.1Very low115 Ų115146.1 Ų146.180%0.80479%0.789SS**  138.1120.1108.766.20000117.4
723V28.6Very low28.3Very low141 Ų141144.1 Ų144.186%0.85578%0.783SS**  trans-154.9125.9160179.90000104.8
724R28.1Very low28.2Very low228 Ų228143.5 Ų143.586%0.8678%0.777SS**  cis93.8110.924.2-161.6-176.2-165.6-177.18.6114.7
725S27.8Very low27.5Very low117 Ų117141.2 Ų141.282%0.81877%0.772SS**  trans-118.9161.1178.754.90000114
726K30.5Very low27.7Very low184 Ų184143.9 Ų143.980%0.877%0.773SS**  trans-164.3163.1176.6-89.2-165.3173-1660106
727S26.6Very low27.7Very low96 Ų96145.1 Ų145.167%0.67178%0.777SS**  cis-164.5136-9.738.10000105.2
728Q30Very low27.7Very low156 Ų156145.6 Ų145.673%0.72977%0.774SS**  60.6114.276.6-157.1-173.5-1.800115.7E730Q728-E730 PolarHBondContact NE2-OE1 3.07Å
729S29.2Very low27.5Very low114 Ų114139.8 Ų139.880%0.79776%0.763SS**  trans172.9164.5142.740.80000110.2
730E29.5Very low27.4Very low144 Ų144139.5 Ų139.567%0.67376%0.762SS**  cis155.2135.3-44-95.8-178.7-170.700110.7Q728Q728-E730 PolarHBondContact NE2-OE1 3.07Å
731M27.1Very low27.4Very low185 Ų185140.6 Ų140.691%0.91177%0.766SS**  trans166.5150.1146.956-177.570.800109.6
732S24.7Very low27.3Very low103 Ų103144 Ų14472%0.7278%0.775SS**  cis-173.4-165.2-15.157.20000105.9
733L27.3Very low27.3Very low141 Ų141143.1 Ų143.174%0.73877%0.769SS**  cis-169.3151.7-12.5-143.467.1000103
734E29.1Very low27.4Very low142 Ų142142.4 Ų142.466%0.66477%0.768SS**  cis-162.7-179.1-14-119.2175.4-143.700106.6F736E734-F736 VanDerWaalsContact CD-CE2 3.49Å; E734-F736 HydrophobicContact CG-CD2 4.31Å; E734-F736 HydrophobicContact CG-CE2 4.13Å; E734-F736 WeakPolarHBondContact OE2-CE2 3.44Å
735G24.3Very low27.4Very low58 Ų58137.2 Ų137.260%0.59876%0.761SS**  cis179.6167.1-1.600000113.3
736F30.3Very low27.5Very low181 Ų181138.2 Ų138.279%0.79476%0.762SS**  trans57.4143.4139.9-67.2-64.1000122.7E734E734-F736 VanDerWaalsContact CD-CE2 3.49Å; E734-F736 HydrophobicContact CG-CD2 4.31Å; E734-F736 HydrophobicContact CG-CE2 4.13Å; E734-F736 WeakPolarHBondContact OE2-CE2 3.44Å
737S27.8Very low27.5Very low109 Ų109134.3 Ų134.376%0.76276%0.764SS**  cis-163.7176.3-3.659.10000108.6
738E25.5Very low27.6Very low169 Ų169134.4 Ų134.479%0.7977%0.771SS**  cis-155.5-173.81.8-158.6-88.8107.800106.2R740E738-R740 PolarHBondContact OE1-N 3.26Å; E738-R740 VanDerWaalsContact OE1-N 3.13Å
739G23.9Very low27.5Very low58 Ų58131.3 Ų131.360%0.59877%0.772SS**  trans147.163141.200000118.9
740R23.5Very low27.5Very low237 Ų237130.8 Ų130.889%0.89478%0.775SS**  trans52.3131.1162.8-86.1-175.9173.1176.1-0.6120.9E738E738-R740 PolarHBondContact OE1-N 3.26Å; E738-R740 VanDerWaalsContact OE1-N 3.13Å
741L26Very low27.8Very low169 Ų169128.4 Ų128.489%0.88578%0.78SS**  trans-99.3150.7169.2-76.5161.3000113.5
742L27.9Very low28.3Very low176 Ų176131.1 Ų131.192%0.92178%0.779SS**  trans-132.9153.2154.9-79175.9000109.5
743S25.4Very low28.8Very low97 Ų97134.3 Ų134.368%0.67878%0.783SS**  trans-104.6137.1-159.7-173.70000114.9V745S743-V745 WeakPolarHBondContact OG-CG2 3.48Å
744P30.3Very low29.2Very low126 Ų126133.5 Ų133.582%0.81878%0.78SS**  trans-99.592.2173.536.1-29.9000112.6
745V29Very low29.9Very low119 Ų119131.4 Ų131.472%0.72178%0.778SS**  trans-112.54.3-178.1170.30000113.7S743S743-V745 WeakPolarHBondContact OG-CG2 3.48Å
746V30.1Very low30.8Very low138 Ų138133.7 Ų133.784%0.83678%0.78SS**SBendtrans-95.9-18.7-168.8-175.20000114.5
747A29.3Very low31.6Very low103 Ų103130.8 Ų130.885%0.85177%0.769SS**THydrogen-bonded Turntrans-81.5-17.1-170.200000115.9
748A28.8Very low32.5Very low97 Ų97130.2 Ų130.280%0.80276%0.757SS**THydrogen-bonded Turntrans-95.2-3.9-167.700000115.4
749A28Very low33.5Very low92 Ų92128.6 Ų128.676%0.7675%0.753SS**SBendtrans-92.4-10.3-169.900000115.3
750A30.5Very low34.5Very low103 Ų103133.1 Ų133.185%0.85176%0.763SS**SBendtrans-93.59.3-167.300000115.5
751A35.5Very low36.1Very low94 Ų94125.8 Ų125.878%0.77774%0.741SS**SBendtrans-123.925.7-166.200000115
752R36.9Very low37.8Very low241 Ų241120.3 Ų120.391%0.90972%0.717SS**  trans-142.4109.8167.2-74.9-170.3175.2179.8-2.3111.1
753Q34.5Very low39Very low170 Ų170118 Ų11879%0.79471%0.71SS**  trans-132.6142.3157.2-74.2-170.7-84.900107.7E757Q753-E757 PolarHBondContact NE2-OE2 3.23Å
754D36.5Very low40.2Very low125 Ų125121 Ų12167%0.66871%0.714SS**  trans-76.5148.4-174.3-83.9-52.2000112.4V756 E757D754-V756 PolarHBondContact O-N 3.4Å; D754-E757 PolarHBondContact O-N 3Å
755P43Very low41.4Very low97 Ų97119.9 Ų119.963%0.6370%0.697SS**THydrogen-bonded Turntrans-65.6-8.3-174.426.9-35.8000114.5
756V44Very low42.6Very low106 Ų106119.8 Ų119.864%0.64268%0.684SS**THydrogen-bonded Turntrans-83.7-39-177.9-174.80000112.3D754 L758 L759D754-V756 PolarHBondContact O-N 3.4Å; V756-L758 VanDerWaalsContact C-N 3.25Å; V756-L758 PolarHBondContact O-N 2.88Å; V756-L759 PolarHBondContact O-N 3.4Å
757E46.4Very low43.3Very low120 Ų120118.4 Ų118.456%0.56167%0.671SS**G310 helixtrans-62.8-36.5175-74-166.112800111.4Q753 D754 L759 L760Q753-E757 PolarHBondContact NE2-OE2 3.23Å; D754-E757 PolarHBondContact O-N 3Å; E757-L759 PolarHBondContact O-N 3.24Å; E757-L760 PolarHBondContact O-N 3.14Å
758L47.8Very low44.3Very low98 Ų98116 Ų11651%0.51365%0.652SS.*G310 helixtrans-62.2-18.7-176.9-126171.7000113.2V756 R766V756-L758 VanDerWaalsContact C-N 3.25Å; V756-L758 PolarHBondContact O-N 2.88Å; L758-R766 PolarHBondContact O-NE 2.94Å; L758-R766 PolarHBondContact O-NH2 3.15Å
759L45.8Very low45.1Very low135 Ų135114.4 Ų114.471%0.70764%0.639SS**G310 helixtrans-85.4-12.6175.5-82.8165.3000114.5V756 E757V756-L759 PolarHBondContact O-N 3.4Å; E757-L759 PolarHBondContact O-N 3.24Å
760L45.2Very low46.1Very low152 Ų152115 Ų11580%0.79663%0.626SS**THydrogen-bonded Turntrans-102.6-10.4-176.2-62176.6000114E757E757-L760 PolarHBondContact O-N 3.14Å
761L56.3Low46.8Very low83 Ų83115.5 Ų115.544%0.43561%0.613SS.*SBendtrans-72.1145.4179.6-72.3168.7000113.1E765 R766L761-E765 HydrophobicContact CD2-CB 4.4Å; L761-R766 HydrophobicContact CB-CG 4.46Å
762S62.4Low47.1Very low55 Ų55118 Ų11839%0.38561%0.609SS.*  trans-69.6159.217674.40000112.3Q764 E765 R766S762-Q764 PolarHBondContact O-N 3.03Å; S762-E765 WeakPolarHBondContact CB-OE2 3.43Å; S762-E765 PolarHBondContact N-OE2 2.88Å; S762-E765 PolarHBondContact O-N 3.36Å; S762-E765 VanDerWaalsContact OG-CD 3.26Å; S762-E765 WeakPolarHBondContact OG-CG 3.37Å; S762-E765 PolarHBondContact OG-N 3.02Å; S762-E765 PolarHBondContact OG-OE2 3.07Å; S762-R766 PolarHBondContact O-N 2.96Å
763T52.5Low47.3Very low127 Ų127110.8 Ų110.878%0.77960%0.601SS**Hα-helixtrans-61.4-29.7178.648.80000113L767T763-L767 PolarHBondContact O-N 3.11Å
764Q52.1Low47.6Very low160 Ų160111.4 Ų111.475%0.74860%0.596SS**Hα-helixtrans-72.5-38.2177.8-174.3171.1-15.700112.2S762 L767 A768S762-Q764 PolarHBondContact O-N 3.03Å; Q764-L767 PolarHBondContact O-N 2.95Å; Q764-A768 PolarHBondContact O-N 2.85Å; Q764-A768 VanDerWaalsContact O-N 3.11Å
765E54.5Low47.5Very low103 Ų103115.6 Ų115.648%0.48160%0.602SS.*Hα-helixtrans-71.4-40.8178.9-68.9160131.800111.8L761 S762 L767 A768 A769L761-E765 HydrophobicContact CD2-CB 4.4Å; S762-E765 WeakPolarHBondContact CB-OE2 3.43Å; S762-E765 PolarHBondContact N-OE2 2.88Å; S762-E765 PolarHBondContact O-N 3.36Å; S762-E765 VanDerWaalsContact OG-CD 3.26Å; S762-E765 WeakPolarHBondContact OG-CG 3.37Å; S762-E765 PolarHBondContact OG-N 3.02Å; S762-E765 PolarHBondContact OG-OE2 3.07Å; E765-L767 VanDerWaalsContact C-N 3.34Å; E765-L767 PolarHBondContact O-N 2.84Å; E765-A768 PolarHBondContact O-N 3.33Å; E765-A769 PolarHBondContact O-N 3.17Å
766R54.5Low46.9Very low117 Ų117114.9 Ų114.944%0.44261%0.605SS.*Hα-helixtrans-57.8-44.7171.8-80-178.9171-179.5-3.3112L758 L761 S762 A768 A769 E770L758-R766 PolarHBondContact O-NE 2.94Å; L758-R766 PolarHBondContact O-NH2 3.15Å; L761-R766 HydrophobicContact CB-CG 4.46Å; S762-R766 PolarHBondContact O-N 2.96Å; R766-A768 VanDerWaalsContact C-N 3.35Å; R766-A768 PolarHBondContact O-N 3.38Å; R766-A769 PolarHBondContact O-N 3.04Å; R766-E770 PolarHBondContact O-N 3.13Å
767L44.1Very low46.4Very low108 Ų108116.1 Ų116.157%0.56562%0.615SS**Hα-helixtrans-64.1-39.1178.9-169.372.4000112T763 Q764 E765 L771T763-L767 PolarHBondContact O-N 3.11Å; Q764-L767 PolarHBondContact O-N 2.95Å; E765-L767 VanDerWaalsContact C-N 3.34Å; E765-L767 PolarHBondContact O-N 2.84Å; L767-L771 HydrophobicContact CG-CD1 4.26Å; L767-L771 WeakPolarHBondContact O-CB 3.38Å; L767-L771 WeakPolarHBondContact O-CG 3.02Å; L767-L771 PolarHBondContact O-N 3.04Å
768A50.1Low45.6Very low54 Ų54118.6 Ų118.645%0.44663%0.631SS.*Hα-helixtrans-64.1-46.717600000111.9Q764 E765 R766 E770 L771 Q772Q764-A768 PolarHBondContact O-N 2.85Å; Q764-A768 VanDerWaalsContact O-N 3.11Å; E765-A768 PolarHBondContact O-N 3.33Å; R766-A768 VanDerWaalsContact C-N 3.35Å; R766-A768 PolarHBondContact O-N 3.38Å; A768-E770 PolarHBondContact O-N 2.96Å; A768-L771 PolarHBondContact O-N 3.25Å; A768-Q772 WeakPolarHBondContact O-CB 3.32Å; A768-Q772 PolarHBondContact O-N 3.46Å
769A47.2Very low44.7Very low63 Ų63118.5 Ų118.552%0.52164%0.644SS.*Hα-helixtrans-61-44177.300000112.3E765 R766 Q772 A773E765-A769 PolarHBondContact O-N 3.17Å; R766-A769 PolarHBondContact O-N 3.04Å; A769-Q772 PolarHBondContact O-N 3.16Å; A769-A773 PolarHBondContact O-N 3.07Å
770E47.4Very low43.8Very low104 Ų104118.8 Ų118.849%0.48665%0.652SS.*Hα-helixtrans-69.2-35.5-179.4-156.7-169.615300112.7R766 A768 Q772 R774R766-E770 PolarHBondContact O-N 3.13Å; A768-E770 PolarHBondContact O-N 2.96Å; E770-Q772 VanDerWaalsContact C-N 3.34Å; E770-R774 WeakPolarHBondContact O-CG 3.35Å; E770-R774 PolarHBondContact O-N 3.45Å; E770-R774 IonicContact OE1-CZ 3.32Å; E770-R774 VanDerWaalsContact OE1-CZ 3.32Å; E770-R774 IonicContact OE1-NE 3.5Å; E770-R774 IonicContact OE1-NH2 2.61Å; E770-R774 PolarHBondContact OE1-NH2 3.36Å
771L46.2Very low42.9Very low114 Ų114120.4 Ų120.460%0.59766%0.657SS**Hα-helixtrans-65.7-36.3171.3-78.8168.6000112.2L767 A768 R774L767-L771 HydrophobicContact CG-CD1 4.26Å; L767-L771 WeakPolarHBondContact O-CB 3.38Å; L767-L771 WeakPolarHBondContact O-CG 3.02Å; L767-L771 PolarHBondContact O-N 3.04Å; A768-L771 PolarHBondContact O-N 3.25Å; L771-R774 PolarHBondContact O-N 3.47Å
772Q41.9Very low41.7Very low146 Ų146125.4 Ų125.468%0.68268%0.679SS**Hα-helixtrans-72.8-34.8-179.1-161.1146.8-41.900112.1A768 A769 E770 R774A768-Q772 WeakPolarHBondContact O-CB 3.32Å; A768-Q772 PolarHBondContact O-N 3.46Å; A769-Q772 PolarHBondContact O-N 3.16Å; E770-Q772 VanDerWaalsContact C-N 3.34Å; Q772-R774 VanDerWaalsContact C-N 3.27Å; Q772-R774 PolarHBondContact O-N 2.83Å
773A39.8Very low40Very low89 Ų89127.7 Ų127.774%0.73670%0.695SS**Hα-helixtrans-67.8-19.7173.700000114.4A769A769-A773 PolarHBondContact O-N 3.07Å
774R40.9Very low39Very low184 Ų184129.1 Ų129.169%0.69470%0.697SS**THydrogen-bonded Turntrans-91.55.1-177.8-70.1179.2-175-149.71.9114.8E770 L771 Q772 A776E770-R774 WeakPolarHBondContact O-CG 3.35Å; E770-R774 PolarHBondContact O-N 3.45Å; E770-R774 IonicContact OE1-CZ 3.32Å; E770-R774 VanDerWaalsContact OE1-CZ 3.32Å; E770-R774 IonicContact OE1-NE 3.5Å; E770-R774 IonicContact OE1-NH2 2.61Å; E770-R774 PolarHBondContact OE1-NH2 3.36Å; L771-R774 PolarHBondContact O-N 3.47Å; Q772-R774 VanDerWaalsContact C-N 3.27Å; Q772-R774 PolarHBondContact O-N 2.83Å; R774-A776 PolarHBondContact O-N 3.15Å
775R34.6Very low37.9Very low213 Ų213125.6 Ų125.680%0.80469%0.69SS**  trans-82.491176.8-79.8-176.4166.9162.4-2.6112.4
776A31.5Very low36.7Very low82 Ų82127.7 Ų127.768%0.67870%0.704SS**PPolyproline II helixtrans-67.3149.816200000111.2R774 L778R774-A776 PolarHBondContact O-N 3.15Å; A776-L778 PolarHBondContact O-N 3.32Å
777P33.7Very low35.5Very low132 Ų132128 Ų12886%0.85772%0.72SS**PPolyproline II helixtrans-70.4125.4177.228.5-33.7000111.1
778L28.4Very low34.8Very low171 Ų171130.6 Ų130.690%0.89573%0.729SS**PPolyproline II helixtrans-76128.6171.9-82.2154.8000110.1A776A776-L778 PolarHBondContact O-N 3.32Å
779A29.2Very low33.7Very low97 Ų97131.6 Ų131.680%0.80273%0.732SS**PPolyproline II helixtrans-71.2137166.900000109.9
780T26.9Very low32.7Very low140 Ų140136 Ų13686%0.85975%0.746SS**PPolyproline II helixtrans-73.4131.6-179.546.60000111.8
781M26.7Very low31.8Very low186 Ų186141.6 Ų141.692%0.91676%0.764SS**  trans-113127.4163.5-87.9-175.659.600110.3
782E30.1Very low30.9Very low189 Ų189140.8 Ų140.888%0.88377%0.768SS**  trans-128.2149.7160.4-69.1-174.3148.400107.2
783S28.6Very low30.2Very low103 Ų103143 Ų14372%0.7278%0.776SS**  cis-164.3177.5-25.9-168.40000107.5
784L30.5Very low29.5Very low157 Ų157145.8 Ų145.882%0.82278%0.778SS**  trans71.2136.3170.5-49177.9000116.1
785S29.1Very low28.9Very low85 Ų85141.3 Ų141.359%0.59478%0.775SS**  cis-168.8139-11.245.60000109.7
786D29.3Very low28.7Very low148 Ų148142.3 Ų142.379%0.79178%0.779SS**  trans55.3145.8136-50.6-18.1000120
787T28.6Very low28.6Very low124 Ų124149.7 Ų149.776%0.76179%0.789SS**  cis-164.5171.3-8.521.30000106.7
788E29.1Very low28.3Very low162 Ų162148.2 Ų148.276%0.75778%0.782SS**  cis-150.51732.5-139.2-164.992.200112.8
789S27.2Very low28.3Very low74 Ų74145.4 Ų145.452%0.51778%0.776SS.*  trans17.8130.314864.10000125.8
790L27.3Very low28.2Very low156 Ų156144 Ų14482%0.81777%0.772SS**  46.1119.2122.8-54.9169.2000120.9
791Y28.4Very low28.3Very low222 Ų222146 Ų14687%0.87177%0.769SS**  -176128.2109.4-110.3-87.8000111.1
792S26.2Very low28.4Very low96 Ų96147.2 Ų147.267%0.67176%0.763SS**  trans50.3156.1130.8-168.50000124.4
793F27.6Very low28.4Very low193 Ų193143.1 Ų143.185%0.84676%0.756SS**  trans-38.4151.3147.4-59.6-101.1000111.4
794D26.5Very low28.3Very low148 Ų148144.3 Ų144.379%0.79175%0.753SS**  cis-157.1-157.144.3-165.2-1.6000112.8
795S28.3Very low28.3Very low89 Ų89148.3 Ų148.362%0.62276%0.757SS**  trans-90.1164.3-164.3-52.30000114.5
796R28.9Very low28.1Very low235 Ų235147.8 Ų147.889%0.88777%0.765SS**  trans108.4135.7151.9-60.2170.5174.6-171.4-1.3118.1
797R29.2Very low28.1Very low237 Ų237146.5 Ų146.589%0.89477%0.767SS**  trans54112.3142.6-76.8-174.6169.6-178.7-3.5120.4
798S27.4Very low28.5Very low101 Ų101146.1 Ų146.171%0.70677%0.767SS**  71.8121.1110.1-156.50000120.3
799S29.9Very low28.3Very low111 Ų111143 Ų14378%0.77676%0.764SS**  trans56124.2136.363.80000120.9
800G27Very low28.4Very low69 Ų69146.3 Ų146.371%0.71178%0.775SS**  trans150.5102.114200000117
801F27.8Very low28.4Very low180 Ų180146.1 Ų146.179%0.78977%0.769SS**  trans36114.2145-83.1-121.5000119.5
802R29.8Very low28.4Very low212 Ų212139.5 Ų139.580%0.876%0.76SS**  88.5124.867-170.5-162.3-155.4-172.813113.1
803S29.4Very low28.5Very low104 Ų104139.9 Ų139.973%0.72776%0.758SS**  131.9160.1126.7-150.90000118.1
804I28Very low28.6Very low128 Ų128137.1 Ų137.166%0.65675%0.752SS**  trans87.4102.8157.4-58.3-172.3000120.4
805R28.8Very low28.8Very low240 Ų240136 Ų13691%0.90674%0.742SS**  trans55.8148.7137.2-61.8176.3-177.1146.2-2.7121.5
806G25.2Very low29Very low74 Ų74139.9 Ų139.976%0.76374%0.743SS**  trans-178.13.6167.800000119.9
807S29.1Very low29.1Very low121 Ų121133.9 Ų133.985%0.84673%0.728SS**  trans-76.6130.8176.455.60000112.1
808P37Very low29.3Very low117 Ų117128.8 Ų128.876%0.7672%0.715SS**  -143.7174.3107.437.2-22000112
809S26.2Very low29.4Very low97 Ų97127 Ų12768%0.67871%0.711SS**  cis-167.7162.4-2048.10000108.8
810L29.1Very low29.3Very low143 Ų143129 Ų12975%0.74971%0.708SS**  trans36.9145.2138.6-62.5167.1000120.3
811H26.1Very low29.4Very low152 Ų152130.9 Ų130.970%0.70470%0.701SS**  cis-167.4172.827.9-144.1-21.9000111.9
812A29.1Very low29.4Very low82 Ų82130.2 Ų130.268%0.67870%0.699SS**  trans85.1135.6132.500000121
813V28.5Very low29.2Very low105 Ų105129.7 Ų129.764%0.63670%0.698SS**  cis-167.6142.4-17.694.60000112.7
814L29.5Very low29Very low135 Ų135131.7 Ų131.771%0.70770%0.699SS**  trans62.2157.4150.9-54.2-178000119
815E31.5Very low28.9Very low124 Ų124132.4 Ų132.458%0.57970%0.704SS**  cis-169178.6-4.7-118.6176.2-167.600108.8
816R31.6Very low30.2Very low171 Ų171125.8 Ų125.865%0.64569%0.693SS**  cis-139175.5-6-73.6-149.683.77818105.3
817D30.6Very low30.2Very low108 Ų108126.7 Ų126.758%0.57869%0.692SS**  cis-176.1168.7-20.1-98.323.6000104.3
818E34.1Very low30.5Very low131 Ų131127.9 Ų127.961%0.61269%0.688SS**  cis-155.1165.6-38.2-131.9-74.258.600104H820E818-H820 PolarHBondContact OE1-N 3.02Å; E818-H820 IonicContact OE2-CE1 3.37Å; E818-H820 PolarHBondContact OE2-CE1 2.9Å; E818-H820 IonicContact OE2-ND1 3.67Å; E818-H820 IonicContact OE2-NE2 3.91Å
819G28.5Very low30.4Very low62 Ų62128.3 Ų128.364%0.63969%0.691SS**  trans178.121.8-177.100000119.5
820H28.9Very low30.6Very low154 Ų154131.8 Ų131.871%0.71370%0.696SS**  trans40.1144.7158.7-57-71.4000122E818E818-H820 PolarHBondContact OE1-N 3.02Å; E818-H820 IonicContact OE2-CE1 3.37Å; E818-H820 PolarHBondContact OE2-CE1 2.9Å; E818-H820 IonicContact OE2-ND1 3.67Å; E818-H820 IonicContact OE2-NE2 3.91Å
821L28.4Very low30.6Very low108 Ų108132.2 Ų132.257%0.56569%0.694SS**  cis-178.9156.2-37.4-115.5172.4000108.8
822F27.8Very low30.7Very low166 Ų166131.1 Ų131.173%0.72869%0.694SS**  trans66.8150.4156.7-68.5-44.2000120.2
823Y24.9Very low31.5Very low201 Ų201133 Ų13379%0.78870%0.699SS**  cis-168.2159.5-18.7-165.5-133.7000111.7
824I26.5Very low31.4Very low146 Ų146134 Ų13475%0.74971%0.71SS**  trans136.3134.2140.9-69.9169.9000112.4
825D24.8Very low31.2Very low143 Ų143135.5 Ų135.577%0.76572%0.718SS**  trans-144.2-169.9171.3-151.618.1000109.1
826P56.2Low31Very low102 Ų102135.1 Ų135.166%0.66273%0.73SS**  -125.7-171.5-113.641.7-23.2000115.2
827A26.3Very low30.8Very low92 Ų92131.5 Ų131.576%0.7673%0.73SS**  trans-147.490.5174.600000115.3
828I34.4Very low30.9Very low146 Ų146136 Ų13675%0.74974%0.739SS**  28.8126.8111.7-61.9176.1000115.8
829P36.1Very low30.6Very low127 Ų127135.5 Ų135.583%0.82575%0.745SS**  -148.9174.370.441.3-22000120.3
830E28.8Very low30.6Very low170 Ų170139.3 Ų139.379%0.79475%0.746SS**  trans-79.2-175.9172.2-46.9163.6128.300111.3
831E30.2Very low30.6Very low151 Ų151138.1 Ų138.171%0.70675%0.745SS**  cis-159.7153.86.1-150.2-161.4-145.400112
832N27.1Very low30.5Very low130 Ų130140 Ų14070%0.69576%0.755SS**  trans59.9159147.9-86-29.9000124.1
833P46.1Very low30.3Very low120 Ų120136.4 Ų136.478%0.77976%0.755SS**  trans-108.6167.9-167.641.7-35.4000115.8
834S26.8Very low30.4Very low126 Ų126131.3 Ų131.388%0.88176%0.755SS**  trans-134.5174171.962.10000112.9
835L26.1Very low30.3Very low167 Ų167131.4 Ų131.487%0.87476%0.757SS**  trans-99.5161.9-165.8-72.7161000114.2
836S25.8Very low30.3Very low117 Ų117128.8 Ų128.882%0.81875%0.75SS**  trans71.1153.6161.7-80.70000117.5
837S28.9Very low28.8Very low94 Ų94131.9 Ų131.966%0.65776%0.76SS**  cis-167.3162.5-1251.10000111.8
838R32.1Very low28.6Very low203 Ų203131.7 Ų131.777%0.76675%0.753SS**  trans66.8126.3170.6-54.7178.278.7127.30.8114
839T27.6Very low28.2Very low120 Ų120133.4 Ų133.474%0.73676%0.755SS**  cis72.1135.144.6-34.10000113.2
840E29.3Very low27.7Very low142 Ų142135.3 Ų135.366%0.66475%0.753SS**  trans82145.1167.8-52.7-162.8133.200116.2
841L27.9Very low27.6Very low129 Ų129132.2 Ų132.268%0.67575%0.75SS**  cis-165.1167.6-8.3-118.9175.1000111
842L26.4Very low27.5Very low148 Ų148132.5 Ų132.578%0.77575%0.751SS**  trans63.2143.7162.5-58.7163.9000116.7
843A24.5Very low27.4Very low90 Ų90131.9 Ų131.974%0.74475%0.748SS**  cis85.888.625.400000116
844A26.1Very low26.6Very low94 Ų94133 Ų13378%0.77775%0.753SS**  trans-157.6121.8142.700000105.3
845D25Very low26.8Very low148 Ų148135.3 Ų135.379%0.79175%0.749SS**  cis84.2132.945.1-160.6-3.8000113.1
846S24.1Very low27.6Very low89 Ų89132 Ų13262%0.62274%0.738SS**  trans70.7127.6161.1-71.40000121.5
847L24.8Very low27.7Very low167 Ų167133.3 Ų133.387%0.87474%0.735SS**  trans69.7155.3153.6-58164.4000117.8
848S23.2Very low27.6Very low87 Ų87136.3 Ų136.361%0.60874%0.739SS**  cis-170.9143.9-28.1600000112.1
849K25.1Very low27.4Very low183 Ų183133 Ų13380%0.79674%0.741SS**  trans63.6159154.6-69.3-179.3176.31790119.8
850H26.3Very low27.5Very low167 Ų167131.3 Ų131.377%0.77374%0.739SS**  trans65.8127.2174.6-60-72.2000116.1
851S25.8Very low27.5Very low104 Ų104132.3 Ų132.373%0.72775%0.748SS**  cis92.2152.725.3-163.60000114.4
852Q27.8Very low27.4Very low158 Ų158129.7 Ų129.774%0.73875%0.752SS**  trans77.6142.3-175.2-52-165.5-93.500115.3
853D26.8Very low27.5Very low116 Ų116128.6 Ų128.662%0.6276%0.756SS**  cis-162.7143.2-18.3-111.4-39.1000110.4
854T27.9Very low27.6Very low145 Ų145127.9 Ų127.989%0.8976%0.758SS**  trans179106.4134.421.20000113.9
855Q32.2Very low27.6Very low173 Ų173126.9 Ų126.981%0.80876%0.757SS**  trans-26.9177.2151.8-77-178.15.100120.1
856P42.1Very low27.9Very low99 Ų99126.1 Ų126.164%0.64376%0.757SS**  cis-137.1173.53.617.29.5000118.6
857L27.6Very low28.2Very low143 Ų143127.9 Ų127.975%0.74976%0.764SS**  trans67.4143.6151.9-96.872.5000119.5
858E27.4Very low29.5Very low157 Ų157125.2 Ų125.273%0.73476%0.757SS**  cis-155.4145-6.2-154.6158.1-138.500112.8
859V28.2Very low29.9Very low135 Ų135128.1 Ų128.182%0.81876%0.761SS**  trans24.1145.7150176.60000121.5
860A29.1Very low30.1Very low83 Ų83129 Ų12969%0.68676%0.759SS**  cis177.9-161.5-23.500000106.8
861L28.4Very low31.3Very low164 Ų164126.3 Ų126.386%0.85976%0.757SS**  cis-161.6117.1-5.8-150.3172.6000111.1
862G27Very low32.7Very low73 Ų73126.4 Ų126.475%0.75376%0.755SS**  trans67.4-175.9159.400000118.7
863S27.8Very low33.1Very low125 Ų125124 Ų12487%0.87476%0.756SS**  cis-166.8143.2-23.3-167.80000112.4
864G27Very low33.5Very low75 Ų75122.7 Ų122.777%0.77376%0.761SS**  trans66.3104.5144.200000124
865G26.8Very low33.8Very low74 Ų74121.6 Ų121.676%0.76376%0.759SS**  93.9146.8103.200000124.4
866V30.2Very low33.8Very low131 Ų131117.5 Ų117.579%0.79476%0.755SS**  trans91.489.3135.5-174.80000122.5
867T30.7Very low33.4Very low126 Ų126118.9 Ų118.977%0.77376%0.757SS**  trans63.9-175.6132.567.70000121.8
868P51.9Low33.5Very low111 Ų111117.6 Ų117.672%0.72175%0.751SS**  -137.5170.1-65.940.3-23.7000118.6
869E32.7Very low33.6Very low148 Ų148118.5 Ų118.569%0.69276%0.755SS**  trans46.7134.9145.5-81.2-138.6118.400126.9
870R29.4Very low33.7Very low202 Ų202120.3 Ų120.376%0.76276%0.755SS**  trans79.3171.4135.7-78.6-177.3178.8-153.7-6.4121.2
871P51Low33.8Very low111 Ų111124.3 Ų124.372%0.72176%0.759SS**  -136.8-130.2-71.943.6-21.5000111.5
872P54.3Low33.9Very low105 Ų105122.8 Ų122.868%0.68276%0.756SS**  -124.8166.4-58.239.9-23.7000116.8
873S36Very low33.9Very low109 Ų109123.1 Ų123.176%0.76276%0.759SS**  trans49.3135.1137.870.20000127.7
874A35.8Very low33.9Very low88 Ų88121.3 Ų121.373%0.72776%0.761SS**  101.4139.8129.600000124.1
875S33.6Very low33.9Very low122 Ų122121.8 Ų121.885%0.85377%0.766SS**  trans65.8164.1158.9400000120
876A33.8Very low33.9Very low87 Ų87122.3 Ų122.372%0.71977%0.771SS**  cis-178.8177.5-28.100000107.7
877N32Very low33.7Very low128 Ų128120.3 Ų120.368%0.68478%0.777SS**  cis-164.1177.1-5.1-133.241.1000110.5
878D30.6Very low33.5Very low116 Ų116118.4 Ų118.462%0.6278%0.782SS**  trans53.9123.6153.5-48.3-30.8000121.9
879E30.2Very low32.3Very low175 Ų175121.5 Ų121.582%0.81879%0.792SS**  77.6149.696.2-64.7-178.3162.700115.4
880E30.2Very low32Very low174 Ų174118.4 Ų118.481%0.81379%0.792SS**  cis-151.6-159.116-143.2-175.1-173.100113.8
881E30.1Very low31.7Very low166 Ų166113.9 Ų113.978%0.77679%0.791SS**  trans-62.6-173.7-166.2-66.4-163.6146.900119.7
882V30.6Very low30.6Very low133 Ų133119.4 Ų119.481%0.80680%0.797SS**  cis-157.2144.428.4-175.20000114.9
883G27.6Very low29.2Very low79 Ų79117.4 Ų117.481%0.81480%0.796SS**  trans88.8142.215100000118
884G27.7Very low28.5Very low87 Ų87119.8 Ų119.890%0.89780%0.795SS**  cis133.1125.50.900000111.2
885G26.9Very low27.9Very low86 Ų86122.8 Ų122.889%0.88780%0.798SS**  cis178.4179.4-6.400000111
886G26.6Very low27.5Very low84 Ų84121.2 Ų121.287%0.86679%0.792SS**  trans125103.1161.200000119.1
887G26.6Very low27Very low90 Ų90124.7 Ų124.793%0.92880%0.798SS**  trans82.9132.314300000119.9
888G25.7Very low26.8Very low85 Ų85126.5 Ų126.588%0.87680%0.802SS**  trans139121.8165.100000114
889L26.7Very low26.5Very low176 Ų176127.3 Ų127.392%0.92181%0.806SS**  trans-129.6144.8178.3-169.375.3000111
890A26.2Very low26.2Very low84 Ų84122.6 Ų122.669%0.69481%0.805SS**  trans85.2141.5158.600000121.5
891S23.9Very low26Very low106 Ų106126 Ų12674%0.74181%0.81SS**  trans60.399.3146.854.70000122.5
892R26.8Very low25.7Very low228 Ų228125.8 Ų125.886%0.8681%0.814SS**  54.4111.3102.9-175.3-175.6177.4177.6-1.6119.4
893G24.6Very low25.7Very low63 Ų63123 Ų12365%0.64981%0.812SS**  trans-108.8164.4134.600000109.7
894E23.1Very low25.8Very low158 Ų158126.1 Ų126.174%0.73881%0.81SS**  cis66.1136.224.4-64.4-162.5161.200114
895L23.3Very low25.9Very low151 Ų151126.6 Ų126.679%0.79180%0.799SS**  cis-153.1163.1-0.5-107.9160000106.9
896A25.2Very low25.9Very low89 Ų89124.6 Ų124.674%0.73677%0.771SS**  cis-151.1-177.25.300000110.8
897L23.2Very low26.4Very low161 Ų161122.4 Ų122.484%0.84374%0.742SS**  trans-147120.4171.8-157.3163.4000112.1
898H26.2Very low26.9Very low165 Ų165121.2 Ų121.276%0.76472%0.718SS**  trans-149.1150.1174.7-91.5-15.7000108.7
899N24.5Very low27.4Very low134 Ų134121.1 Ų121.172%0.71770%0.695SS**  cis-153132.1-10.5-125.7-13.3000109
900G24.2Very low27.9Very low76 Ų76115 Ų11578%0.78467%0.665SS**  trans-125.392.5179.200000111.5L902G900-L902 PolarHBondContact O-N 2.85Å
901R25.3Very low28.4Very low245 Ų245114.9 Ų114.993%0.92565%0.652SS**  trans-79.5110.2171.8-81.3-174.7174.2-176.8-1.6110.3
902L25.6Very low29.1Very low162 Ų162113.6 Ų113.685%0.84863%0.634SS**  trans-127.5142.6136.1-85.298.1000107.8G900G900-L902 PolarHBondContact O-N 2.85Å
903G29.2Very low29.5Very low75 Ų75108.9 Ų108.977%0.77362%0.62SS**  trans-127123.8170.700000107.9
904D29.7Very low30.1Very low143 Ų143108.1 Ų108.177%0.76561%0.608SS**PPolyproline II helixtrans-100.8122.4177.6-71.2-55.7000109.9
905S29.6Very low30.9Very low97 Ų97106.7 Ų106.768%0.67860%0.601SS**PPolyproline II helixtrans-69.3164.5169.551.20000111.3
906P27.5Very low31.5Very low45 Ų45103.7 Ų103.729%0.29258%0.582SS.*SBendtrans-53.2153.6163.726-36.4000110.9W305 L309W305-P906 HydrophobicContact CZ3-CB 4.14Å; L309-P906 HydrophobicContact CD1-CB 4.09Å
907S37Very low32Very low37 Ų37102 Ų10226%0.25956%0.56SS.*PPolyproline II helixtrans-62.9130.1-174.5580000111.1Q909 V910S907-Q909 PolarHBondContact O-N 2.97Å; S907-Q909 VanDerWaalsContact O-N 3.13Å; S907-V910 PolarHBondContact O-N 3.5Å
908P37.9Very low32.6Very low66 Ų6697.2 Ų97.243%0.42954%0.535SS..Hα-helixtrans-61.1-29.1-173.923.2-33.6000112V910 L911 E912P908-V910 PolarHBondContact O-N 2.97Å; P908-L911 CarbonylContact O-C 3.52Å; P908-L911 WeakPolarHBondContact O-CA 3.41Å; P908-L911 PolarHBondContact O-N 2.84Å; P908-E912 HydrophobicContact CB-CG 4.32Å; P908-E912 WeakPolarHBondContact O-CB 3.47Å; P908-E912 WeakPolarHBondContact O-CG 3.39Å; P908-E912 PolarHBondContact O-N 2.76Å
909Q35.8Very low33.2Very low82 Ų8294 Ų9438%0.38353%0.532SS..Hα-helixtrans-40.5-41.8174.5-70.1153.46.100115.7T205 S907 F913T205-Q909 HydrophobicContact CG2-CG 3.59Å; S907-Q909 PolarHBondContact O-N 2.97Å; S907-Q909 VanDerWaalsContact O-N 3.13Å; Q909-F913 WeakPolarHBondContact O-CB 3.48Å; Q909-F913 PolarHBondContact O-N 3.31Å; Q909-F913 VanDerWaalsContact O-N 3.09Å
910V37.3Very low33.5Very low48 Ų4890.4 Ų90.429%0.29151%0.512SS..Hα-helixtrans-78.1-36.2-176.9-176.80000111.1P306 S907 P908 A914P306-V910 HydrophobicContact CB-CG1 4.33Å; S907-V910 PolarHBondContact O-N 3.5Å; P908-V910 PolarHBondContact O-N 2.97Å; V910-A914 WeakPolarHBondContact O-CB 3.11Å; V910-A914 PolarHBondContact O-N 3.4Å
911L36.5Very low34Very low81 Ų8189.9 Ų89.942%0.42449%0.488SS..Hα-helixtrans-72.7-48.7174.8-66.8167.6000110.2P908 F913 A914 E915P908-L911 CarbonylContact O-C 3.52Å; P908-L911 WeakPolarHBondContact O-CA 3.41Å; P908-L911 PolarHBondContact O-N 2.84Å; L911-F913 VanDerWaalsContact C-N 3.32Å; L911-F913 PolarHBondContact O-N 3.29Å; L911-A914 PolarHBondContact O-N 2.97Å; L911-A914 VanDerWaalsContact O-N 3.14Å; L911-E915 WeakPolarHBondContact O-CB 3.41Å; L911-E915 WeakPolarHBondContact O-CG 3.49Å; L911-E915 PolarHBondContact O-N 3.38Å
912E38.4Very low34.5Very low80 Ų8081.5 Ų81.537%0.37446%0.462SS..Hα-helixtrans-58.9-37.2177.7-71.9173.1169.600112.8P908 F916P908-E912 HydrophobicContact CB-CG 4.32Å; P908-E912 WeakPolarHBondContact O-CB 3.47Å; P908-E912 WeakPolarHBondContact O-CG 3.39Å; P908-E912 PolarHBondContact O-N 2.76Å; E912-F916 WeakPolarHBondContact O-CB 3.38Å; E912-F916 PolarHBondContact O-N 2.71Å
913F35.8Very low34.9Very low129 Ų12976 Ų7657%0.56643%0.433SS*.Hα-helixtrans-71.2-41.2175.1-177.2-110.2000112.1Q909 L911 F916 I917Q909-F913 WeakPolarHBondContact O-CB 3.48Å; Q909-F913 PolarHBondContact O-N 3.31Å; Q909-F913 VanDerWaalsContact O-N 3.09Å; L911-F913 VanDerWaalsContact C-N 3.32Å; L911-F913 PolarHBondContact O-N 3.29Å; F913-F916 PolarHBondContact O-N 3.35Å; F913-I917 HydrophobicContact CD2-CG1 4.42Å; F913-I917 HydrophobicContact CE1-CG1 4.31Å; F913-I917 HydrophobicContact CE2-CD1 4.28Å; F913-I917 HydrophobicContact CE2-CG1 4.03Å; F913-I917 HydrophobicContact CZ-CD1 4.32Å; F913-I917 HydrophobicContact CZ-CG1 3.98Å; F913-I917 WeakPolarHBondContact O-CG1 3.46Å; F913-I917 PolarHBondContact O-N 3.13Å
914A37.3Very low35.1Very low47 Ų4774.2 Ų74.239%0.38841%0.405SS..Hα-helixtrans-64-45.3174.500000111.4V910 L911 I917 D918V910-A914 WeakPolarHBondContact O-CB 3.11Å; V910-A914 PolarHBondContact O-N 3.4Å; L911-A914 PolarHBondContact O-N 2.97Å; L911-A914 VanDerWaalsContact O-N 3.14Å; A914-I917 PolarHBondContact O-N 3.06Å; A914-D918 WeakPolarHBondContact O-CB 3.23Å; A914-D918 PolarHBondContact O-N 3.34Å
915E39Very low35.3Very low128 Ų12871.9 Ų71.960%0.59840%0.401SS*.Hα-helixtrans-67-33.9176.5-72.8177.9-179.500112.6L911 S919L911-E915 WeakPolarHBondContact O-CB 3.41Å; L911-E915 WeakPolarHBondContact O-CG 3.49Å; L911-E915 PolarHBondContact O-N 3.38Å; E915-S919 WeakPolarHBondContact O-CA 3.34Å; E915-S919 WeakPolarHBondContact O-CB 3.43Å; E915-S919 PolarHBondContact O-N 3.02Å
916F36.9Very low35.3Very low88 Ų8875.1 Ų75.139%0.38640%0.402SS..Hα-helixtrans-67.4-43.7173.9172.2-105.4000112E912 F913 L920E912-F916 WeakPolarHBondContact O-CB 3.38Å; E912-F916 PolarHBondContact O-N 2.71Å; F913-F916 PolarHBondContact O-N 3.35Å; F916-L920 HydrophobicContact CD1-CD1 4.19Å; F916-L920 HydrophobicContact CD2-CD1 4.5Å; F916-L920 HydrophobicContact CE1-CD1 3.69Å; F916-L920 HydrophobicContact CE2-CD1 4.04Å; F916-L920 HydrophobicContact CZ-CD1 3.62Å; F916-L920 WeakPolarHBondContact O-CG 3.48Å; F916-L920 PolarHBondContact O-N 2.61Å
917I35.6Very low35.3Very low52 Ų5278.4 Ų78.427%0.26743%0.426SS..Hα-helixtrans-69.2-40.2176.2-66.7-64.7000110.7L647 F913 A914 L920 F921L647-I917 HydrophobicContact CD1-CG2 3.9Å; L647-I917 HydrophobicContact CD2-CG2 4.42Å; F913-I917 HydrophobicContact CD2-CG1 4.42Å; F913-I917 HydrophobicContact CE1-CG1 4.31Å; F913-I917 HydrophobicContact CE2-CD1 4.28Å; F913-I917 HydrophobicContact CE2-CG1 4.03Å; F913-I917 HydrophobicContact CZ-CD1 4.32Å; F913-I917 HydrophobicContact CZ-CG1 3.98Å; F913-I917 WeakPolarHBondContact O-CG1 3.46Å; F913-I917 PolarHBondContact O-N 3.13Å; A914-I917 PolarHBondContact O-N 3.06Å; I917-L920 PolarHBondContact O-N 3.22Å; I917-F921 WeakPolarHBondContact O-CD2 3.46Å
918D36.3Very low34.8Very low62 Ų6281.7 Ų81.733%0.33245%0.449SS..Hα-helixtrans-67.1-48.2175.3-16361000111A914 L920 F921 N922A914-D918 WeakPolarHBondContact O-CB 3.23Å; A914-D918 PolarHBondContact O-N 3.34Å; D918-L920 PolarHBondContact O-N 3.17Å; D918-F921 PolarHBondContact O-N 3.26Å; D918-N922 WeakPolarHBondContact O-CB 3.38Å; D918-N922 PolarHBondContact O-N 2.89Å; D918-N922 WeakPolarHBondContact OD2-CB 3.37Å; D918-N922 PolarHBondContact OD2-ND2 3.22Å
919S37.7Very low34.4Very low98 Ų9881.2 Ų81.269%0.68545%0.448SS*.Hα-helixtrans-60-20.8177.4-178.90000114.3E915E915-S919 WeakPolarHBondContact O-CA 3.34Å; E915-S919 WeakPolarHBondContact O-CB 3.43Å; E915-S919 PolarHBondContact O-N 3.02Å
920L31.6Very low34.1Very low58 Ų5886.2 Ų86.230%0.30447%0.468SS..Hα-helixtrans-78.3-20.8174.4-88.2168.2000113.8F916 I917 D918F916-L920 HydrophobicContact CD1-CD1 4.19Å; F916-L920 HydrophobicContact CD2-CD1 4.5Å; F916-L920 HydrophobicContact CE1-CD1 3.69Å; F916-L920 HydrophobicContact CE2-CD1 4.04Å; F916-L920 HydrophobicContact CZ-CD1 3.62Å; F916-L920 WeakPolarHBondContact O-CG 3.48Å; F916-L920 PolarHBondContact O-N 2.61Å; I917-L920 PolarHBondContact O-N 3.22Å; D918-L920 PolarHBondContact O-N 3.17Å
921F34.1Very low33.9Very low65 Ų6590.6 Ų90.629%0.28549%0.486SS..Hα-helixtrans-133.1-17.6-170.3-67.5-84.7000114.9L240 M646 L647 I917 D918 L923L240-F921 HydrophobicContact CD1-CD1 3.87Å; L240-F921 HydrophobicContact CD1-CE1 3.61Å; M646-F921 HydrophobicContact CE-CD1 3.58Å; M646-F921 HydrophobicContact CE-CE1 3.86Å; M646-F921 HydrophobicContact CE-CG 4.3Å; L647-F921 HydrophobicContact CD1-CB 3.83Å; L647-F921 HydrophobicContact CD1-CD1 4.45Å; L647-F921 HydrophobicContact CD1-CD2 3.39Å; L647-F921 HydrophobicContact CD1-CE2 4.03Å; L647-F921 HydrophobicContact CD1-CG 3.65Å; I917-F921 WeakPolarHBondContact O-CD2 3.46Å; D918-F921 PolarHBondContact O-N 3.26Å; F921-L923 PolarHBondContact O-N 3.02Å
922N36.8Very low33.4Very low69 Ų6991.9 Ų91.937%0.36949%0.493SS..  trans-87.895.3-179-167.40.8000110.9D918D918-N922 WeakPolarHBondContact O-CB 3.38Å; D918-N922 PolarHBondContact O-N 2.89Å; D918-N922 WeakPolarHBondContact OD2-CB 3.37Å; D918-N922 PolarHBondContact OD2-ND2 3.22Å
923L33.4Very low33.1Very low45 Ų4595.9 Ų95.924%0.23652%0.516CS..  trans-93.13.3-176.6-72.6169.7000114.4I237 V241 I556 A559 F921I237-L923 HydrophobicContact CG2-CD1 4.11Å; I237-L923 HydrophobicContact CG2-CD2 3.84Å; I237-L923 HydrophobicContact CG2-CG 4.47Å; V241-L923 HydrophobicContact CG2-CD1 3.41Å; V241-L923 VanDerWaalsContact CG2-CD1 3.41Å; I556-L923 HydrophobicContact CG2-CD2 4.34Å; A559-L923 HydrophobicContact CB-CD1 4.11Å; F921-L923 PolarHBondContact O-N 3.02Å
924D32Very low32.7Very low38 Ų3899 Ų9920%0.20353%0.526CS..  trans-85.9117.4174.8-91.1-10.7000109.9K561 K926K561-D924 VanDerWaalsContact CE-OD2 3.29Å; K561-D924 WeakPolarHBondContact CE-OD2 3.38Å; K561-D924 IonicContact NZ-OD1 3.42Å; K561-D924 IonicContact NZ-OD2 3.61Å; K561-D924 PolarHBondContact NZ-OD2 2.88Å; D924-K926 PolarHBondContact O-N 3.48Å
925S33.8Very low32.2Very low95 Ų95102.1 Ų102.166%0.66454%0.543SS*.  trans-73.456.7170.863.90000111.8
926K30.8Very low31.7Very low165 Ų165104.3 Ų104.372%0.71756%0.555SS**  trans-113.871.7163.5-79.1-161.7172.4-1670108.9D924 S928D924-K926 PolarHBondContact O-N 3.48Å; K926-S928 PolarHBondContact O-N 3.38Å
927S26.4Very low31.3Very low113 Ų113106.5 Ų106.579%0.7958%0.576SS**  trans-64.182.8155.455.90000108.7S929S927-S929 PolarHBondContact O-N 3Å
928S27.6Very low30.9Very low106 Ų106110.3 Ų110.374%0.74160%0.601SS**  trans-62.497.1156.950.50000105.9K926K926-S928 PolarHBondContact O-N 3.38Å
929S29.4Very low30.5Very low57 Ų57112.9 Ų112.940%0.39962%0.621SS.*  trans-62.9151.8-176.175.10000108.8S927 Q931 D932S927-S929 PolarHBondContact O-N 3Å; S929-Q931 PolarHBondContact O-N 3.47Å; S929-Q931 WeakPolarHBondContact OG-CB 3.42Å; S929-Q931 PolarHBondContact OG-N 3.28Å; S929-D932 PolarHBondContact N-OD2 3.46Å; S929-D932 PolarHBondContact O-N 3.44Å; S929-D932 VanDerWaalsContact O-N 3.12Å; S929-D932 PolarHBondContact OG-OD2 3.37Å
930F30.5Very low29.9Very low186 Ų186117.4 Ų117.482%0.81663%0.632SS**THydrogen-bonded Turntrans-59.7-10.1177.6-148.8-94.7000112.8
931Q31.5Very low29.6Very low141 Ų141120.3 Ų120.366%0.65966%0.657SS**THydrogen-bonded Turntrans-75.7-36.1177.7-140.368.825.300113.8S929 L933 Y934S929-Q931 PolarHBondContact O-N 3.47Å; S929-Q931 WeakPolarHBondContact OG-CB 3.42Å; S929-Q931 PolarHBondContact OG-N 3.28Å; Q931-L933 VanDerWaalsContact C-N 3.26Å; Q931-L933 PolarHBondContact O-N 3.39Å; Q931-Y934 WeakPolarHBondContact O-CB 3.2Å; Q931-Y934 PolarHBondContact O-N 3.48Å; Q931-Y934 VanDerWaalsContact O-N 3.14Å
932D27.5Very low29.6Very low108 Ų108122.8 Ų122.858%0.57868%0.679SS**G310 helixtrans-72.7-21.3-169.2-62.8-58.4000112.8S929 Y934S929-D932 PolarHBondContact N-OD2 3.46Å; S929-D932 PolarHBondContact O-N 3.44Å; S929-D932 VanDerWaalsContact O-N 3.12Å; S929-D932 PolarHBondContact OG-OD2 3.37Å; D932-Y934 PolarHBondContact O-N 3.27Å
933L30.3Very low29.1Very low164 Ų164126.7 Ų126.786%0.85971%0.706SS**G310 helixtrans-71.9-10.5174.8-13979.6000113.4Q931Q931-L933 VanDerWaalsContact C-N 3.26Å; Q931-L933 PolarHBondContact O-N 3.39Å
934Y29.1Very low28.8Very low195 Ų195129 Ų12977%0.76573%0.725SS**G310 helixtrans-91.4-7.6-173.5-115.3-84.3000115Q931 D932Q931-Y934 WeakPolarHBondContact O-CB 3.2Å; Q931-Y934 PolarHBondContact O-N 3.48Å; Q931-Y934 VanDerWaalsContact O-N 3.14Å; D932-Y934 PolarHBondContact O-N 3.27Å
935C26.9Very low28.6Very low112 Ų112133.1 Ų133.176%0.75775%0.748SS**SBendtrans-106.9-2.1-170-70.70000115.9
936M27.2Very low28.6Very low173 Ų173139.3 Ų139.385%0.85276%0.758SS**SBendtrans-128.927.9-171.1-73.5-120.7-69.700116.5
937V29.1Very low28.6Very low135 Ų135135.9 Ų135.982%0.81876%0.761SS**  trans-144.782.8157.1-168.60000111.9
938V26.3Very low28.7Very low132 Ų132140.3 Ų140.380%0.877%0.769SS**  trans-143.3118.8159.2-175.90000109.1
939P27.8Very low28.9Very low116 Ų116138.1 Ų138.175%0.75376%0.763SS**  trans-81.7142.816832.8-32.3000111.1
940E26.6Very low29Very low193 Ų193142 Ų14290%0.90279%0.787SS**  trans-73.1137.7-178.9-58.7-177.8126.200113.3
941S24.3Very low28.9Very low119 Ų119142.9 Ų142.983%0.83279%0.79SS**  trans-169155.3142.314.90000111.1
942P34.8Very low29Very low116 Ų116141.4 Ų141.475%0.75380%0.796SS**  trans-112.9153.8-156.340.3-33.4000115.9
943T26.8Very low29.3Very low151 Ų151141.3 Ų141.393%0.92680%0.801SS**  trans-169169.8138.17.70000111.3
944S26.5Very low29.7Very low93 Ų93137.5 Ų137.565%0.6579%0.788SS**  trans-94-178.8-172.358.10000112.6
945D27.5Very low30.1Very low125 Ų125135.9 Ų135.967%0.66879%0.787SS**  cis-158.7153.525.9-107.6-52000114.4
946Y33.3Very low30.6Very low225 Ų225138 Ų13888%0.88279%0.786SS**  trans52.8169.8157.8-77.3-80.1000122.7
947A31.6Very low31.4Very low94 Ų94135.2 Ų135.278%0.77777%0.771SS**  trans-154.1155.6-163.100000113.7
948E27.4Very low32.4Very low205 Ų205134.6 Ų134.696%0.95876%0.762SS**  trans-160.4163.1154.3-125.4-179.2-165.300111.3
949G32.3Very low33Very low61 Ų61134.7 Ų134.763%0.62976%0.757SS**  trans-138.5138.1-175.900000113.6
950P31.5Very low33.7Very low137 Ų137135 Ų13589%0.8975%0.752SS**PPolyproline II helixtrans-84.5156.9-167.833.1-36.4000115.2
951K29Very low34.5Very low205 Ų205136.2 Ų136.289%0.89175%0.748SS**PPolyproline II helixtrans-101.2165.6178.2-64.2169-1771670111.5
952S33Very low35.4Very low111 Ų111134.6 Ų134.678%0.77674%0.742SS**PPolyproline II helixtrans-79.8150.9-178.2550000114.4
953P34.9Very low35.5Very low106 Ų106136.2 Ų136.269%0.68874%0.74SS**PPolyproline II helixtrans-77.3172.418032.3-36.2000114.2E957P953-E957 VanDerWaalsContact CB-OE2 3.29Å; P953-E957 WeakPolarHBondContact CB-OE2 3.4Å
954S38.2Very low36.2Very low83 Ų83137.5 Ų137.558%0.5873%0.733SS**  trans-108.4165.9-169.671.40000114.4Q956 E957S954-Q956 PolarHBondContact O-N 3.05Å; S954-E957 PolarHBondContact O-N 3.42Å
955Q36.6Very low36.6Very low161 Ų161141.8 Ų141.875%0.75274%0.743SS**THydrogen-bonded Turntrans-60.3-16.6-171.9-70176.6-5300115.5E957 I958Q955-E957 VanDerWaalsContact C-N 3.34Å; Q955-E957 PolarHBondContact O-N 3.42Å; Q955-I958 WeakPolarHBondContact O-CB 3.39Å; Q955-I958 PolarHBondContact O-N 3.02Å
956Q37.4Very low36.8Very low156 Ų156141.2 Ų141.273%0.72975%0.746SS**Hα-helixtrans-72.4-26.3-174.6-158.3162.8-0.500112.9S954 I958S954-Q956 PolarHBondContact O-N 3.05Å; Q956-I958 VanDerWaalsContact C-N 3.33Å
957E44.3Very low36.6Very low116 Ų116137.8 Ų137.854%0.54274%0.743SS.*Hα-helixtrans-73.3-24.1171.8-65.5-170117.100113.1P953 S954 Q955P953-E957 VanDerWaalsContact CB-OE2 3.29Å; P953-E957 WeakPolarHBondContact CB-OE2 3.4Å; S954-E957 PolarHBondContact O-N 3.42Å; Q955-E957 VanDerWaalsContact C-N 3.34Å; Q955-E957 PolarHBondContact O-N 3.42Å
958I51.4Low36.6Very low121 Ų121141.4 Ų141.462%0.62175%0.748SS**Hα-helixtrans-71-39.8-177-56.1179.9000110.3Q955 Q956 L960 R961Q955-I958 WeakPolarHBondContact O-CB 3.39Å; Q955-I958 PolarHBondContact O-N 3.02Å; Q956-I958 VanDerWaalsContact C-N 3.33Å; I958-L960 PolarHBondContact O-N 2.58Å; I958-R961 PolarHBondContact O-N 3.11Å
959L38.9Very low36.6Very low134 Ų134137.9 Ų137.970%0.70274%0.74SS**Hα-helixtrans-70-30.3-179-75.2166.5000113.4R961 A962L959-R961 VanDerWaalsContact C-N 3.3Å; L959-R961 PolarHBondContact O-N 3.47Å; L959-A962 PolarHBondContact O-N 3.2Å
960L41Very low36.6Very low124 Ų124140.9 Ų140.965%0.64975%0.748SS**Hα-helixtrans-70.7-23.6177.3-78.3166.6000113.4I958 A962I958-L960 PolarHBondContact O-N 2.58Å; L960-A962 VanDerWaalsContact C-N 3.3Å; L960-A962 PolarHBondContact O-N 3.45Å
961R43.7Very low36.4Very low217 Ų217143.8 Ų143.882%0.81975%0.747SS**G310 helixtrans-74.1-15.4174.3-94.3-173.1168.996.6-2114.2I958 L959 Q963I958-R961 PolarHBondContact O-N 3.11Å; L959-R961 VanDerWaalsContact C-N 3.3Å; L959-R961 PolarHBondContact O-N 3.47Å; R961-Q963 PolarHBondContact O-N 3.37Å
962A42.6Very low36.3Very low85 Ų85139.6 Ų139.670%0.70274%0.741SS**G310 helixtrans-85.60.8-172.100000115.1L959 L960L959-A962 PolarHBondContact O-N 3.2Å; L960-A962 VanDerWaalsContact C-N 3.3Å; L960-A962 PolarHBondContact O-N 3.45Å
963Q38.3Very low36.2Very low151 Ų151140.6 Ų140.671%0.70675%0.745SS**G310 helixtrans-100.6-4.9-173.5-69.2-170.7-21.500115.4R961R961-Q963 PolarHBondContact O-N 3.37Å
964F40.5Very low35.9Very low178 Ų178146.9 Ų146.978%0.78176%0.755SS**SBendtrans-128.570.9-174.3-70.1-85000112.9
965E35.8Very low35.4Very low183 Ų183151.2 Ų151.286%0.85577%0.771SS**  trans174.2101.5146.3-101.9170.3-151.100111.7
966P30.4Very low35Very low112 Ų112153.1 Ų153.173%0.72778%0.777SS**  trans-100.4136.4173.235.2-30000113.2
967N30.9Very low34.5Very low154 Ų154150 Ų15082%0.82478%0.778SS**  trans79.198168.4-47.4-63.5000118.1
968L29.9Very low33.6Very low169 Ų169148.3 Ų148.389%0.88579%0.791SS**  trans-123112.5156.9-87.8165000109.8
969V28.1Very low32.4Very low132 Ų132148.3 Ų148.380%0.880%0.802SS**  trans-134.4123.1169.5-179.80000108
970P31.2Very low31.8Very low123 Ų123145.4 Ų145.480%0.79980%0.797SS**  trans-78.9152.3-169.431.1-35.6000113.4
971K27.4Very low31.2Very low199 Ų199146.5 Ų146.587%0.86580%0.803SS**  trans-121.8143.5166.1-77.6-178.4176.4174.80110.5
972P28.1Very low31.1Very low117 Ų117140.8 Ų140.876%0.7679%0.794SS**PPolyproline II helixtrans-75.1161.3-173.530.7-36.2000113.5
973P30.5Very low30.3Very low132 Ų132141.9 Ų141.986%0.85780%0.797SS**PPolyproline II helixtrans-73154.8-173.130.4-36.7000113.6
974R28.2Very low29.9Very low238 Ų238140.4 Ų140.490%0.89880%0.803SS**PPolyproline II helixtrans-104143168.2-76.7-176.1171.6177.1-3.7111
975L27.9Very low29.3Very low174 Ų174135 Ų13591%0.91180%0.798SS**PPolyproline II helixtrans-75.1155172.1-66.3137.5000110.8
976F28.2Very low29Very low201 Ų201134.3 Ų134.388%0.88280%0.798SS**  trans-122.9122.1162.6-94-84.1000110.2
977A27.4Very low28.8Very low91 Ų91134.2 Ų134.275%0.75280%0.8SS**  trans-71.4157.8143.900000107.8
978G25Very low28.6Very low79 Ų79135 Ų13581%0.81480%0.804SS**  cis121.4102.113.100000108.5
979S27.1Very low28.5Very low121 Ų121132.3 Ų132.385%0.84680%0.799SS**  trans-151110.9179.8-162.20000109
980A26.6Very low28.8Very low73 Ų73131.9 Ų131.960%0.60380%0.798SS**  trans-75.4-172.3140.600000107.2
981D27.3Very low28.6Very low147 Ų147131.2 Ų131.279%0.78680%0.797SS**  cis-171.3-173.923.5-128.2-25.5000105.7
982P42.4Very low28.6Very low97 Ų97131.3 Ų131.363%0.6380%0.798SS**  cis-137.6-174.1-13.636.1-15.9000115.2
983S26.2Very low28.9Very low109 Ų109131.3 Ų131.376%0.76280%0.798SS**  trans80.2142.1148.975.50000119.3
984S28.8Very low28.8Very low119 Ų119133.4 Ų133.483%0.83280%0.801SS**  cis-174.1147.3-17.151.30000111.9
985G27Very low28.7Very low64 Ų64128 Ų12866%0.6680%0.8SS**  trans134.5107.2167.800000112.8
986I29.6Very low28.8Very low170 Ų170124.4 Ų124.487%0.87279%0.789SS**  69.8120.170-61.3168.9000111.1
987S27.6Very low29Very low109 Ų109120.6 Ų120.676%0.76279%0.787SS**  cis-158.7157.3-2.450.40000114.8
988L27.2Very low29Very low172 Ų172120.1 Ų120.190%0.90179%0.792SS**  trans-35.4152164.5-63.6159.5000117.2
989S27.1Very low29.4Very low112 Ų112125.3 Ų125.378%0.78380%0.795SS**  trans-99.1153.5168.245.40000112.5
990P33.7Very low29.5Very low122 Ų122126.4 Ų126.479%0.79279%0.79SS**  trans-90.4145.8179.234.9-33.9000113.3
991S27.9Very low29.6Very low110 Ų110129.8 Ų129.877%0.76980%0.795SS**  trans-114.2143.4170.456.90000111
992F27.2Very low29.6Very low200 Ų200128.5 Ų128.588%0.87779%0.788SS**  trans-133.9154.9167-91.1-86.8000111.5
993P34.4Very low28.9Very low118 Ų118129.9 Ų129.977%0.76679%0.79SS**  trans-104.5178.4-155.440.8-36.6000115.5
994L28Very low29Very low175 Ų175130.7 Ų130.792%0.91679%0.79SS**  trans-66.1158.5175.3-63.1160.5000113.5
995S26.5Very low30Very low126 Ų126130.8 Ų130.888%0.88179%0.788SS**  trans-136.4156.2161-172.30000109.4
996S29.1Very low30Very low98 Ų98134.8 Ų134.869%0.68580%0.8SS**  trans-129.7138.7-160.659.50000115.3
997S33.3Very low29.9Very low120 Ų120129.6 Ų129.684%0.83979%0.788SS**  trans53.1125143.662.90000120.5
998G28Very low29.9Very low82 Ų82133.2 Ų133.285%0.84580%0.798SS**  trans176.97316600000114.7
999E32Very low29.8Very low188 Ų188130.3 Ų130.388%0.87979%0.792SS**  trans-94.8145.5166-65.8-174.6130.600110.8
1000L30.1Very low29.9Very low144 Ų144129.7 Ų129.775%0.75479%0.788SS**  159.9161.2109.5-157.566.9000111.1
1001M29.1Very low29.8Very low144 Ų144130.9 Ų130.971%0.70978%0.783SS**  trans76.4138.2167-46.5-56.8-74.600117.3
1002D27.3Very low29.9Very low119 Ų119133.3 Ų133.364%0.63678%0.782SS**  cis-163166.2-26.1-140.8-8.1000113.3
1003L27.4Very low29.9Very low126 Ų126128.5 Ų128.566%0.6677%0.772SS**  trans45.298.8148.7-73.3164.7000123
1004T28.6Very low29.8Very low127 Ų127130.7 Ų130.778%0.77978%0.776SS**  60.1157121.949.50000123.4
1005P48Very low29.9Very low120 Ų120126.5 Ų126.578%0.77977%0.767SS**  trans-106.2160.9-156.840.4-35.5000116.8
1006T28.5Very low30.2Very low148 Ų148124.4 Ų124.491%0.90876%0.757SS**  trans-131.6153159.948.40000110.6
1007G27.2Very low30.2Very low61 Ų61125.6 Ų125.663%0.62976%0.756SS**  trans-128.1-170.6173.700000111.5
1008L28.3Very low30.2Very low185 Ų185127.2 Ų127.297%0.96975%0.748SS**  trans75144.5-166.9-52158.7000112.2
1009S24.9Very low30.5Very low111 Ų111129.6 Ų129.678%0.77674%0.74SS**  cis-141.81670.658.70000112.4
1010S28.9Very low30.4Very low100 Ų100131 Ų13170%0.69974%0.737SS**  trans-67.3159.1166.949.20000113.1
1011Q30.3Very low30.4Very low147 Ų147129.8 Ų129.869%0.68774%0.736SS**  156.8130.8107.8-173.1160.5-2.600113.4
1012E30Very low30.4Very low161 Ų161128.6 Ų128.675%0.75274%0.742SS**  trans65.3152.7154.6-81.6167.1-139.200120.8
1013C28.4Very low30.6Very low98 Ų98129 Ų12966%0.66275%0.749SS**  cis-161.4162.1-18.2-146.60000111.7
1014L30.9Very low31.8Very low164 Ų164127.8 Ų127.886%0.85975%0.748SS**  trans64.2151.7164.3-56.6171.4000116.6
1015A31.7Very low31.9Very low88 Ų88128.5 Ų128.573%0.72775%0.753SS**  cis-172.4160-13.800000107.3
1016A31.2Very low31.1Very low81 Ų81126 Ų12667%0.66975%0.749SS**  cis-168.3173.4-16.700000108.5
1017D31Very low31.2Very low124 Ų124129 Ų12966%0.66375%0.752SS**  trans65.4139.5159.5-74.45000119.9
1018K33.5Very low31.4Very low154 Ų154129.6 Ų129.667%0.6776%0.758SS**  cis-167.3144.24.8-122.5166.9-176.7135.50112.6
1019I32.5Very low31.5Very low131 Ų131125.7 Ų125.767%0.67275%0.752SS**  trans63.6140.1138.5-75.5171.8000118.4
1020R30.6Very low32Very low218 Ų218126 Ų12682%0.82375%0.754SS**  cis-154.51712.8-134176.8-172.9138.9-1.2112.6
1021T30Very low33.1Very low119 Ų119126.7 Ų126.773%0.7376%0.756SS**  trans-77.3154.8164.946.60000113.9
1022S29.1Very low33.2Very low119 Ų119123.9 Ų123.983%0.83276%0.758SS**  175.5155.5119.646.70000114.8
1023T31.2Very low33.3Very low128 Ų128125.9 Ų125.979%0.78576%0.764SS**  trans-92.7-164165.658.30000109.2
1024P53.2Low33.6Very low99 Ų99129.5 Ų129.564%0.64377%0.772SS**  cis-135.9-160.8-1334.2-11000113.6
1025T31.2Very low33.7Very low143 Ų143129.9 Ų129.988%0.87778%0.775SS**  trans71.6152.9158.964.80000119.4
1026G29.6Very low33.8Very low67 Ų67134.1 Ų134.169%0.69178%0.779SS**  cis161.1139.7-13.300000116
1027H32.5Very low33.8Very low212 Ų212137.6 Ų137.698%0.98179%0.786SS**  trans64.7157.5168-69.3-72.8000120.7
1028G30.1Very low33.8Very low72 Ų72137 Ų13774%0.74279%0.787SS**  trans118.766.3177.200000113.9
1029A31.1Very low33.8Very low104 Ų104137 Ų13786%0.8679%0.792SS**  76.6114.279.900000115.3
1030S34.8Very low33.7Very low116 Ų116136.5 Ų136.581%0.81180%0.801SS**  trans-74.7176166.5-1260000110.8
1031P51.5Low33.8Very low115 Ų115130.5 Ų130.575%0.74780%0.798SS**  cis-148.2170.630.743.2-22.6000120.1
1032A33.1Very low34Very low88 Ų88140.2 Ų140.273%0.72782%0.821SS**  trans55.8123.6141.700000122.6
1033K31.3Very low34.2Very low203 Ų203141.3 Ų141.388%0.88382%0.82SS**  -162.1172.3110-113176.8179-174.60113.4
1034Q34.8Very low34.4Very low175 Ų175141.9 Ų141.982%0.81882%0.822SS**  trans-83.1159.6177.1-58.9152.3-88.300111.1
1035D33.3Very low33.3Very low172 Ų172144.3 Ų144.392%0.9283%0.832SS**  trans-157.5159.2135.6-100.4-30.4000110.3
1036E34.1Very low33.4Very low176 Ų176144.4 Ų144.482%0.82283%0.829SS**  trans-96.9157.9179.5-60.9176.1115.600111.6
1037L32Very low33.7Very low155 Ų155149.3 Ų149.381%0.81284%0.838SS**  173134.3120.2-110.379000114.4
1038V31.1Very low33.8Very low111 Ų111145.1 Ų145.167%0.67383%0.828SS**  trans63.7101.2135.7176.80000121.3
1039I32.8Very low34Very low154 Ų154150.3 Ų150.379%0.7983%0.834SS**  40.1116.7119.5-50.3159.9000118.7
1040S29.8Very low34.2Very low121 Ų121153.8 Ų153.885%0.84683%0.833SS**  -171.3164.5102.7-157.80000112.9
1041A33.8Very low34.2Very low92 Ų92157 Ų15776%0.7683%0.834SS**  trans-80.1147-168.800000115.2
1042R32.7Very low32.6Very low322 Ų322160.8 Ų160.8100%1.21584%0.842SS**  -1520115-128.5177.7-174.4174.91.6112.5

Retrieved 1,042 of 1,042 residues in 360.9 ms (Link to these results)