A0A096NJP2_PAPAN Loading...

Solute carrier family 5 member 4

AlphaFold DB , UniProt , Accession A0A096NJP2, Species PAPAN (Papio anubis, Olive baboon), Gene SLC5A4, Length 659 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37.2	Very low	29.1	Very low	248 Å²	248	136.6 Å²	136.6	100%	1.222	84%	0.84	S	S	*	*				0	93.6	0	-75.8	176.3	-179.4	0	0	107.1
2	A	30.1	Very low	28.9	Very low	99 Å²	99	140.5 Å²	140.5	82%	0.818	84%	0.842	S	S	*	*			trans	-110.4	120.3	176	0	0	0	0	0	106.3
3	S	30.8	Very low	28.9	Very low	121 Å²	121	139.5 Å²	139.5	85%	0.846	84%	0.837	S	S	*	*			trans	-96	113.4	178.9	-62.8	0	0	0	0	109.1
4	T	30.1	Very low	28.9	Very low	133 Å²	133	138 Å²	138	82%	0.816	83%	0.832	S	S	*	*			trans	-67.5	126	170	40.8	0	0	0	0	111.1
5	V	31.5	Very low	29.2	Very low	141 Å²	141	140.9 Å²	140.9	86%	0.855	83%	0.833	S	S	*	*			trans	-120.2	112.8	158.3	179.2	0	0	0	0	106.9
6	S	26	Very low	29.8	Very low	101 Å²	101	137.9 Å²	137.9	71%	0.706	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-66.6	145.8	178	-53	0	0	0	0	111.2	S8	S6-S8 PolarHBondContact O-N 2.59Å
7	P	30	Very low	30.7	Very low	119 Å²	119	133.9 Å²	133.9	77%	0.773	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-71	125.8	164.8	-3.8	20.8	0	0	0	108.4	T9	P7-T9 PolarHBondContact O-N 2.79Å
8	S	27.5	Very low	32.2	Very low	104 Å²	104	130.8 Å²	130.8	73%	0.727	78%	0.781	S	S	*	*	P	Polyproline II helix	trans	-60.5	116.8	167.8	47.9	0	0	0	0	109.6	S6 M10	S6-S8 PolarHBondContact O-N 2.59Å; S8-M10 PolarHBondContact O-N 3.17Å
9	T	25.3	Very low	33.6	Very low	136 Å²	136	125.4 Å²	125.4	83%	0.834	75%	0.748	S	S	*	*			trans	-61.2	99.4	167.5	-36	0	0	0	0	108.4	P7 T11	P7-T9 PolarHBondContact O-N 2.79Å; T9-T11 PolarHBondContact O-N 3.46Å
10	M	28	Very low	34.9	Very low	166 Å²	166	120.4 Å²	120.4	82%	0.818	72%	0.719	S	S	*	*			trans	-71.5	116.2	158.9	-72.6	-157.3	179.1	0	0	106.5	S8 E12	S8-M10 PolarHBondContact O-N 3.17Å; M10-E12 VanDerWaalsContact C-N 3.33Å; M10-E12 PolarHBondContact O-N 3.44Å
11	T	24	Very low	36.1	Very low	135 Å²	135	118 Å²	118	83%	0.828	70%	0.703	S	S	*	*			trans	-58.8	98.5	162.4	20.8	0	0	0	0	107.9	T9 T13	T9-T11 PolarHBondContact O-N 3.46Å; T11-T13 PolarHBondContact O-N 3.09Å
12	E	26.5	Very low	37.3	Very low	183 Å²	183	109.4 Å²	109.4	86%	0.855	66%	0.657	S	S	*	*			trans	-58	106.1	160.1	-76.7	178.2	164.1	0	0	107	M10	M10-E12 VanDerWaalsContact C-N 3.33Å; M10-E12 PolarHBondContact O-N 3.44Å
13	T	28.2	Very low	39	Very low	127 Å²	127	105.1 Å²	105.1	78%	0.779	62%	0.62	S	S	*	*	P	Polyproline II helix	trans	-54.7	124.8	159.1	30.7	0	0	0	0	107.2	T11 E15	T11-T13 PolarHBondContact O-N 3.09Å; T13-E15 PolarHBondContact O-N 3.16Å
14	P	29.3	Very low	40.8	Very low	119 Å²	119	106 Å²	106	77%	0.773	61%	0.611	S	S	*	*	P	Polyproline II helix	trans	-57.6	127.2	-179	21.8	-30.9	0	0	0	109
15	E	33	Very low	43.3	Very low	182 Å²	182	100.9 Å²	100.9	85%	0.85	58%	0.579	S	S	*	*	P	Polyproline II helix	trans	-52.6	133	172.4	-73.7	-173.4	152	0	0	108.6	T13	T13-E15 PolarHBondContact O-N 3.16Å
16	P	38.8	Very low	45.9	Very low	93 Å²	93	97.8 Å²	97.8	60%	0.604	57%	0.568	S	S	*	*	P	Polyproline II helix	trans	-57.9	139.1	177.5	22.3	-30.6	0	0	0	109
17	P	45.3	Very low	48.8	Very low	69 Å²	69	95 Å²	95	45%	0.448	55%	0.551	S	S	.	*	P	Polyproline II helix	trans	-57.5	148.8	179.5	25.4	-34.4	0	0	0	109.8	L19 D21 R22	P17-L19 PolarHBondContact O-N 3.36Å; P17-D21 HydrophobicContact CB-CB 4.11Å; P17-R22 HydrophobicContact CG-CG 4.37Å
18	P	58.5	Low	51.4	Low	79 Å²	79	89.4 Å²	89.4	51%	0.513	51%	0.514	S	S	.	.	P	Polyproline II helix	trans	-52.9	141.2	178.7	21.5	-30.7	0	0	0	109.3	S20 D21	P18-S20 PolarHBondContact O-N 3.09Å; P18-D21 WeakPolarHBondContact CD-OD2 3.28Å; P18-D21 HydrophobicContact CG-CB 4.49Å; P18-D21 VanDerWaalsContact CG-OD2 3.24Å; P18-D21 WeakPolarHBondContact CG-OD2 3.3Å; P18-D21 WeakPolarHBondContact O-CB 3.43Å; P18-D21 PolarHBondContact O-N 3.17Å
19	L	58.4	Low	54.1	Low	28 Å²	28	88.5 Å²	88.5	15%	0.147	50%	0.501	C	S	.	.	H	α-helix	trans	-50.4	-30.3	-170	-113	95	0	0	0	113.9	P17 R22 L171 L371 E372	P17-L19 PolarHBondContact O-N 3.36Å; L19-R22 PolarHBondContact O-N 3Å; L19-L171 WeakPolarHBondContact CB-O 3Å; L19-L371 HydrophobicContact CD2-CB 3.3Å; L19-L371 HydrophobicContact CD2-CD1 3.15Å; L19-L371 HydrophobicContact CD2-CD2 4.3Å; L19-L371 HydrophobicContact CD2-CG 3.67Å; L19-L371 HydrophobicContact CG-CB 4.21Å; L19-E372 WeakPolarHBondContact CD1-OE1 3.45Å
20	S	59.2	Low	57.1	Low	25 Å²	25	85 Å²	85	18%	0.175	48%	0.481	C	S	.	.	H	α-helix	trans	-62.4	-36.4	175.6	54.4	0	0	0	0	114.1	P18 R22 I23 A172	P18-S20 PolarHBondContact O-N 3.09Å; S20-R22 PolarHBondContact O-N 2.69Å; S20-I23 PolarHBondContact O-N 2.75Å; S20-A172 WeakPolarHBondContact CA-O 3.5Å
21	D	60.3	Low	59.9	Low	71 Å²	71	79.1 Å²	79.1	38%	0.38	46%	0.455	S	S	.	.	H	α-helix	trans	-70.4	-26.1	-178.1	-68.5	-7.5	0	0	0	111.2	P17 P18 I23 Q24	P17-D21 HydrophobicContact CB-CB 4.11Å; P18-D21 WeakPolarHBondContact CD-OD2 3.28Å; P18-D21 HydrophobicContact CG-CB 4.49Å; P18-D21 VanDerWaalsContact CG-OD2 3.24Å; P18-D21 WeakPolarHBondContact CG-OD2 3.3Å; P18-D21 WeakPolarHBondContact O-CB 3.43Å; P18-D21 PolarHBondContact O-N 3.17Å; D21-I23 VanDerWaalsContact C-N 3.26Å; D21-I23 PolarHBondContact O-N 3.2Å; D21-Q24 WeakPolarHBondContact O-CB 3.47Å; D21-Q24 PolarHBondContact O-N 3.35Å; D21-Q24 PolarHBondContact OD1-NE2 2.96Å
22	R	63.2	Low	62.8	Low	67 Å²	67	74.3 Å²	74.3	25%	0.253	42%	0.424	S	S	.	.	H	α-helix	trans	-66.6	-30.3	176.1	-56.9	-170.1	178.6	-171.3	11.6	111.8	P17 L19 S20 Q24 N25 E372 R379	P17-R22 HydrophobicContact CG-CG 4.37Å; L19-R22 PolarHBondContact O-N 3Å; S20-R22 PolarHBondContact O-N 2.69Å; R22-Q24 VanDerWaalsContact C-N 3.29Å; R22-Q24 PolarHBondContact O-N 3.22Å; R22-N25 PolarHBondContact O-ND2 2.7Å; R22-E372 IonicContact CZ-OE1 3.67Å; R22-E372 IonicContact CZ-OE2 3.21Å; R22-E372 IonicContact NH1-OE1 3.04Å; R22-E372 IonicContact NH1-OE2 2.64Å; R22-E372 PolarHBondContact NH1-OE2 2.9Å; R22-E372 IonicContact NH2-OE1 3.67Å; R22-E372 PolarHBondContact NH2-OE1 3.17Å; R22-E372 IonicContact NH2-OE2 3.87Å; R22-E372 PolarHBondContact NH2-OE2 2.96Å; R22-R379 VanDerWaalsContact CB-NH1 3.31Å; R22-R379 PolarHBondContact O-NH2 3.2Å
23	I	65.9	Low	65.5	Low	9 Å²	9	69.3 Å²	69.3	5%	0.046	41%	0.405	C	S	.	.	H	α-helix	trans	-78.5	-13.4	-179.7	-69.1	155	0	0	0	112.3	S20 D21 N25 I32 A172 L371 L383	S20-I23 PolarHBondContact O-N 2.75Å; D21-I23 VanDerWaalsContact C-N 3.26Å; D21-I23 PolarHBondContact O-N 3.2Å; I23-N25 PolarHBondContact O-N 3.36Å; I23-I32 HydrophobicContact CG2-CD1 4.48Å; I23-A172 VanDerWaalsContact CD1-C 3.48Å; I23-A172 HydrophobicContact CD1-CB 3.63Å; I23-A172 WeakPolarHBondContact CD1-O 3.16Å; I23-L371 HydrophobicContact CD1-CD2 3.62Å; I23-L371 HydrophobicContact CG1-CD2 4.29Å; I23-L383 HydrophobicContact CD1-CD1 3.44Å; I23-L383 VanDerWaalsContact CD1-CD1 3.44Å; I23-L383 HydrophobicContact CG1-CD1 3.72Å; I23-L383 HydrophobicContact CG2-CD1 4.41Å
24	Q	68.9	Low	68.4	Low	138 Å²	138	68.2 Å²	68.2	65%	0.645	39%	0.394	S	S	*	.			trans	-74	30.5	178.8	-58.9	179.3	16	0	0	113.8	D21 R22	D21-Q24 WeakPolarHBondContact O-CB 3.47Å; D21-Q24 PolarHBondContact O-N 3.35Å; D21-Q24 PolarHBondContact OD1-NE2 2.96Å; R22-Q24 VanDerWaalsContact C-N 3.29Å; R22-Q24 PolarHBondContact O-N 3.22Å
25	N	81.7	Confident	71.1	Confident	27 Å²	27	63.1 Å²	63.1	14%	0.144	36%	0.359	C	S	.	.	S	Bend	trans	-98.4	146.6	171.2	69	87.3	0	0	0	110.5	R22 I23 A27 D28 I29 R379	R22-N25 PolarHBondContact O-ND2 2.7Å; I23-N25 PolarHBondContact O-N 3.36Å; N25-A27 PolarHBondContact O-N 3.26Å; N25-A27 WeakPolarHBondContact OD1-CB 3.32Å; N25-A27 PolarHBondContact OD1-N 2.77Å; N25-D28 VanDerWaalsContact ND2-CG 3.32Å; N25-D28 PolarHBondContact ND2-OD2 2.79Å; N25-D28 PolarHBondContact O-N 3.39Å; N25-D28 PolarHBondContact OD1-N 3.27Å; N25-I29 WeakPolarHBondContact O-CG1 3.43Å; N25-I29 PolarHBondContact O-N 3.24Å; N25-R379 PolarHBondContact ND2-NH2 3.33Å
26	A	86.4	Confident	73.5	Confident	76 Å²	76	57.1 Å²	57.1	63%	0.628	33%	0.33	S	S	*	.	H	α-helix	trans	-61	-30	-175.4	0	0	0	0	0	113.2	S30	A26-S30 WeakPolarHBondContact O-CB 3.3Å; A26-S30 PolarHBondContact O-N 3.22Å; A26-S30 PolarHBondContact O-OG 2.88Å
27	A	86.6	Confident	75.7	Confident	43 Å²	43	57.2 Å²	57.2	36%	0.355	33%	0.325	S	S	.	.	H	α-helix	trans	-67.9	-50.9	-179.9	0	0	0	0	0	111.6	N25 I29 S30 V31	N25-A27 PolarHBondContact O-N 3.26Å; N25-A27 WeakPolarHBondContact OD1-CB 3.32Å; N25-A27 PolarHBondContact OD1-N 2.77Å; A27-I29 PolarHBondContact O-N 2.81Å; A27-S30 PolarHBondContact O-N 3.31Å; A27-V31 VanDerWaalsContact O-CG2 3.28Å; A27-V31 WeakPolarHBondContact O-CG2 3.24Å; A27-V31 PolarHBondContact O-N 2.68Å
28	D	84.7	Confident	77.6	Confident	0 Å²	0	57.1 Å²	57.1	0%	0	32%	0.324	C	S	.	.	H	α-helix	trans	-60.6	-47.6	177.9	-76.5	-21.1	0	0	0	111.3	N25 S30 V31 I32 G377 R379 G380	N25-D28 VanDerWaalsContact ND2-CG 3.32Å; N25-D28 PolarHBondContact ND2-OD2 2.79Å; N25-D28 PolarHBondContact O-N 3.39Å; N25-D28 PolarHBondContact OD1-N 3.27Å; D28-S30 PolarHBondContact O-N 3.23Å; D28-V31 PolarHBondContact O-N 2.88Å; D28-I32 WeakPolarHBondContact O-CD1 3.15Å; D28-I32 WeakPolarHBondContact O-CG1 3.21Å; D28-I32 PolarHBondContact O-N 3.44Å; D28-G377 WeakPolarHBondContact OD1-CA 3.46Å; D28-G377 PolarHBondContact OD1-N 2.86Å; D28-R379 IonicContact OD2-CZ 2.91Å; D28-R379 VanDerWaalsContact OD2-CZ 3.27Å; D28-R379 IonicContact OD2-NE 3.46Å; D28-R379 PolarHBondContact OD2-NE 3.34Å; D28-R379 IonicContact OD2-NH2 3.43Å; D28-R379 PolarHBondContact OD2-NH2 3.45Å; D28-G380 WeakPolarHBondContact OD1-CA 3.49Å; D28-G380 PolarHBondContact OD1-N 2.95Å
29	I	84.5	Confident	78.7	Confident	86 Å²	86	54.3 Å²	54.3	44%	0.441	31%	0.305	S	S	.	.	H	α-helix	trans	-62.1	-45.1	179.8	-63.7	172.5	0	0	0	111.1	N25 A27 V31 I32 V33	N25-I29 WeakPolarHBondContact O-CG1 3.43Å; N25-I29 PolarHBondContact O-N 3.24Å; A27-I29 PolarHBondContact O-N 2.81Å; I29-V31 VanDerWaalsContact C-N 3.34Å; I29-V31 PolarHBondContact O-N 3.09Å; I29-I32 PolarHBondContact O-N 3.41Å; I29-V33 HydrophobicContact CG2-CG2 4.45Å; I29-V33 WeakPolarHBondContact O-CG2 3.44Å; I29-V33 PolarHBondContact O-N 2.8Å
30	S	87.3	Confident	79.6	Confident	61 Å²	61	57.8 Å²	57.8	43%	0.427	32%	0.322	S	S	.	.	H	α-helix	trans	-62.1	-43.2	179.9	-61.3	0	0	0	0	111.4	A26 A27 D28 I32 V33 I34	A26-S30 WeakPolarHBondContact O-CB 3.3Å; A26-S30 PolarHBondContact O-N 3.22Å; A26-S30 PolarHBondContact O-OG 2.88Å; A27-S30 PolarHBondContact O-N 3.31Å; D28-S30 PolarHBondContact O-N 3.23Å; S30-I32 VanDerWaalsContact C-N 3.34Å; S30-I32 PolarHBondContact O-N 3.21Å; S30-V33 PolarHBondContact O-N 3.16Å; S30-I34 WeakPolarHBondContact O-CB 3.23Å; S30-I34 WeakPolarHBondContact O-CD1 3.44Å; S30-I34 WeakPolarHBondContact O-CG1 3.46Å; S30-I34 PolarHBondContact O-N 3.34Å
31	V	88	Confident	80.8	Confident	43 Å²	43	59.3 Å²	59.3	26%	0.261	34%	0.335	S	S	.	.	H	α-helix	trans	-62.9	-42.2	177	171.4	0	0	0	0	111	A27 D28 I29 I34 Y35 L381	A27-V31 VanDerWaalsContact O-CG2 3.28Å; A27-V31 WeakPolarHBondContact O-CG2 3.24Å; A27-V31 PolarHBondContact O-N 2.68Å; D28-V31 PolarHBondContact O-N 2.88Å; I29-V31 VanDerWaalsContact C-N 3.34Å; I29-V31 PolarHBondContact O-N 3.09Å; V31-I34 PolarHBondContact O-N 3.42Å; V31-Y35 VanDerWaalsContact O-CB 3.25Å; V31-Y35 WeakPolarHBondContact O-CB 3.34Å; V31-Y35 PolarHBondContact O-N 3.42Å; V31-L381 HydrophobicContact CG1-CB 3.73Å; V31-L381 HydrophobicContact CG1-CD1 3.96Å; V31-L381 HydrophobicContact CG1-CG 4.46Å
32	I	84.4	Confident	81.8	Confident	35 Å²	35	57.8 Å²	57.8	18%	0.179	33%	0.329	C	S	.	.	H	α-helix	trans	-59.3	-50.1	176.3	-67	159.3	0	0	0	111.4	I23 D28 I29 S30 I34 Y35 F36 G380 S384	I23-I32 HydrophobicContact CG2-CD1 4.48Å; D28-I32 WeakPolarHBondContact O-CD1 3.15Å; D28-I32 WeakPolarHBondContact O-CG1 3.21Å; D28-I32 PolarHBondContact O-N 3.44Å; I29-I32 PolarHBondContact O-N 3.41Å; S30-I32 VanDerWaalsContact C-N 3.34Å; S30-I32 PolarHBondContact O-N 3.21Å; I32-I34 PolarHBondContact O-N 2.89Å; I32-Y35 PolarHBondContact O-N 3.25Å; I32-F36 HydrophobicContact CG2-CD2 3.81Å; I32-F36 HydrophobicContact CG2-CE2 3.85Å; I32-F36 WeakPolarHBondContact O-CD2 3.44Å; I32-F36 PolarHBondContact O-N 2.92Å; I32-G380 WeakPolarHBondContact CG1-O 3.35Å; I32-S384 WeakPolarHBondContact CA-OG 3.47Å; I32-S384 WeakPolarHBondContact CG1-OG 3.11Å
33	V	83.7	Confident	82.4	Confident	77 Å²	77	54.7 Å²	54.7	47%	0.467	32%	0.318	S	S	.	.	H	α-helix	trans	-61.5	-47.8	179.9	173.3	0	0	0	0	110.9	I29 S30 Y35 F36 L37	I29-V33 HydrophobicContact CG2-CG2 4.45Å; I29-V33 WeakPolarHBondContact O-CG2 3.44Å; I29-V33 PolarHBondContact O-N 2.8Å; S30-V33 PolarHBondContact O-N 3.16Å; V33-Y35 VanDerWaalsContact C-N 3.31Å; V33-Y35 PolarHBondContact O-N 3.4Å; V33-F36 PolarHBondContact O-N 3.11Å; V33-L37 HydrophobicContact CG1-CD1 4Å; V33-L37 HydrophobicContact CG1-CG 4.4Å; V33-L37 VanDerWaalsContact O-CG 3.28Å; V33-L37 WeakPolarHBondContact O-CG 3.34Å; V33-L37 PolarHBondContact O-N 2.94Å
34	I	88.5	Confident	83	Confident	104 Å²	104	58.2 Å²	58.2	53%	0.533	34%	0.336	S	S	.	.	H	α-helix	trans	-59.5	-44.3	178.7	-69.3	166	0	0	0	110.6	S30 V31 I32 L37 V38	S30-I34 WeakPolarHBondContact O-CB 3.23Å; S30-I34 WeakPolarHBondContact O-CD1 3.44Å; S30-I34 WeakPolarHBondContact O-CG1 3.46Å; S30-I34 PolarHBondContact O-N 3.34Å; V31-I34 PolarHBondContact O-N 3.42Å; I32-I34 PolarHBondContact O-N 2.89Å; I34-L37 PolarHBondContact O-N 3.46Å; I34-V38 HydrophobicContact CG2-CG2 4.39Å; I34-V38 WeakPolarHBondContact O-CG2 3.4Å; I34-V38 PolarHBondContact O-N 3.37Å
35	Y	86.6	Confident	83.6	Confident	12 Å²	12	58.3 Å²	58.3	5%	0.047	33%	0.331	C	S	.	.	H	α-helix	trans	-58.5	-51.6	179.4	176.6	-85.4	0	0	0	111.7	V31 I32 V33 L37 V38 V39 I210 L381 S384 V385 A388	V31-Y35 VanDerWaalsContact O-CB 3.25Å; V31-Y35 WeakPolarHBondContact O-CB 3.34Å; V31-Y35 PolarHBondContact O-N 3.42Å; I32-Y35 PolarHBondContact O-N 3.25Å; V33-Y35 VanDerWaalsContact C-N 3.31Å; V33-Y35 PolarHBondContact O-N 3.4Å; Y35-L37 VanDerWaalsContact C-N 3.3Å; Y35-L37 PolarHBondContact O-N 3.06Å; Y35-V38 PolarHBondContact O-N 3.11Å; Y35-V39 HydrophobicContact CD1-CG2 4.13Å; Y35-V39 HydrophobicContact CE1-CG2 3.63Å; Y35-V39 HydrophobicContact CE2-CG2 4.38Å; Y35-V39 WeakPolarHBondContact O-CG2 3.15Å; Y35-V39 PolarHBondContact O-N 3.44Å; Y35-I210 HydrophobicContact CD2-CD1 4.05Å; Y35-I210 HydrophobicContact CE2-CB 4.48Å; Y35-I210 HydrophobicContact CE2-CD1 3.58Å; Y35-I210 HydrophobicContact CE2-CG2 4.2Å; Y35-L381 HydrophobicContact CD2-CD1 4.22Å; Y35-S384 VanDerWaalsContact CD1-CB 3.45Å; Y35-V385 HydrophobicContact CD2-CG2 4.34Å; Y35-V385 HydrophobicContact CE2-CG2 3.65Å; Y35-A388 HydrophobicContact CE1-CB 3.47Å; Y35-A388 VanDerWaalsContact CE1-CB 3.47Å; Y35-A388 WeakPolarHBondContact OH-CB 3.35Å
36	F	82.6	Confident	83.3	Confident	56 Å²	56	57.1 Å²	57.1	25%	0.246	33%	0.325	C	S	.	.	H	α-helix	trans	-64.4	-34.8	179.6	-82.2	-70.5	0	0	0	112.5	I32 V33 M40 M187 L387 I391	I32-F36 HydrophobicContact CG2-CD2 3.81Å; I32-F36 HydrophobicContact CG2-CE2 3.85Å; I32-F36 WeakPolarHBondContact O-CD2 3.44Å; I32-F36 PolarHBondContact O-N 2.92Å; V33-F36 PolarHBondContact O-N 3.11Å; F36-M40 VanDerWaalsContact O-CB 3.26Å; F36-M40 WeakPolarHBondContact O-CB 3.5Å; F36-M40 PolarHBondContact O-N 2.95Å; F36-M187 HydrophobicContact CE1-CE 4.15Å; F36-L387 HydrophobicContact CZ-CB 4.05Å; F36-I391 HydrophobicContact CE1-CD1 4.08Å
37	L	84.3	Confident	82.6	Confident	95 Å²	95	54.4 Å²	54.4	50%	0.497	30%	0.299	S	S	.	.	H	α-helix	trans	-63.2	-42.6	173.3	-71.5	175.6	0	0	0	112.1	V33 I34 Y35 M40 A41	V33-L37 HydrophobicContact CG1-CD1 4Å; V33-L37 HydrophobicContact CG1-CG 4.4Å; V33-L37 VanDerWaalsContact O-CG 3.28Å; V33-L37 WeakPolarHBondContact O-CG 3.34Å; V33-L37 PolarHBondContact O-N 2.94Å; I34-L37 PolarHBondContact O-N 3.46Å; Y35-L37 VanDerWaalsContact C-N 3.3Å; Y35-L37 PolarHBondContact O-N 3.06Å; L37-M40 HydrophobicContact CD2-CE 3.8Å; L37-M40 PolarHBondContact O-N 3.46Å; L37-A41 VanDerWaalsContact O-CB 3.31Å; L37-A41 WeakPolarHBondContact O-CB 3.35Å; L37-A41 PolarHBondContact O-N 3.23Å
38	V	85.5	Confident	81.8	Confident	68 Å²	68	58.7 Å²	58.7	41%	0.412	32%	0.315	S	S	.	.	H	α-helix	trans	-65.7	-45.9	177.6	173.7	0	0	0	0	110.9	I34 Y35 M40 A41 V42 L206	I34-V38 HydrophobicContact CG2-CG2 4.39Å; I34-V38 WeakPolarHBondContact O-CG2 3.4Å; I34-V38 PolarHBondContact O-N 3.37Å; Y35-V38 PolarHBondContact O-N 3.11Å; V38-M40 VanDerWaalsContact C-N 3.34Å; V38-M40 PolarHBondContact O-N 3.33Å; V38-A41 PolarHBondContact O-N 3.44Å; V38-V42 WeakPolarHBondContact O-CG2 3.49Å; V38-V42 PolarHBondContact O-N 3.26Å; V38-L206 HydrophobicContact CG1-CD2 3.83Å
39	V	81.1	Confident	81.2	Confident	20 Å²	20	67.9 Å²	67.9	12%	0.121	35%	0.35	C	S	.	.	H	α-helix	trans	-60	-45.9	177.3	172.7	0	0	0	0	110.7	Y35 A41 V42 G43 T203 L206	Y35-V39 HydrophobicContact CD1-CG2 4.13Å; Y35-V39 HydrophobicContact CE1-CG2 3.63Å; Y35-V39 HydrophobicContact CE2-CG2 4.38Å; Y35-V39 WeakPolarHBondContact O-CG2 3.15Å; Y35-V39 PolarHBondContact O-N 3.44Å; V39-A41 PolarHBondContact O-N 3.05Å; V39-V42 PolarHBondContact O-N 3.19Å; V39-G43 PolarHBondContact O-N 3.29Å; V39-T203 HydrophobicContact CG1-CG2 4.14Å; V39-L206 HydrophobicContact CG2-CD2 4.18Å
40	M	78.8	Confident	80.2	Confident	101 Å²	101	65.4 Å²	65.4	50%	0.498	34%	0.339	S	S	.	.	H	α-helix	trans	-61.5	-42.7	176.3	-176.5	175.9	62.3	0	0	111.8	F36 L37 V38 V42 G43 L44	F36-M40 VanDerWaalsContact O-CB 3.26Å; F36-M40 WeakPolarHBondContact O-CB 3.5Å; F36-M40 PolarHBondContact O-N 2.95Å; L37-M40 HydrophobicContact CD2-CE 3.8Å; L37-M40 PolarHBondContact O-N 3.46Å; V38-M40 VanDerWaalsContact C-N 3.34Å; V38-M40 PolarHBondContact O-N 3.33Å; M40-V42 PolarHBondContact O-N 2.94Å; M40-G43 PolarHBondContact O-N 2.93Å; M40-L44 HydrophobicContact CG-CD1 4.03Å; M40-L44 HydrophobicContact CG-CG 4.41Å; M40-L44 WeakPolarHBondContact O-CB 3.49Å; M40-L44 VanDerWaalsContact O-CG 3.28Å; M40-L44 WeakPolarHBondContact O-CG 3.15Å; M40-L44 PolarHBondContact O-N 3.05Å
41	A	83.1	Confident	79	Confident	56 Å²	56	66.2 Å²	66.2	46%	0.463	34%	0.339	S	S	.	.	H	α-helix	trans	-62.2	-43.2	177.4	0	0	0	0	0	112.2	L37 V38 V39 L44 W45	L37-A41 VanDerWaalsContact O-CB 3.31Å; L37-A41 WeakPolarHBondContact O-CB 3.35Å; L37-A41 PolarHBondContact O-N 3.23Å; V38-A41 PolarHBondContact O-N 3.44Å; V39-A41 PolarHBondContact O-N 3.05Å; A41-L44 PolarHBondContact O-N 2.97Å; A41-W45 VanDerWaalsContact O-CB 3.26Å; A41-W45 WeakPolarHBondContact O-CB 3.42Å; A41-W45 PolarHBondContact O-N 2.83Å
42	V	81.6	Confident	77.8	Confident	39 Å²	39	65 Å²	65	24%	0.236	33%	0.33	C	S	.	.	H	α-helix	trans	-65.5	-43.1	176	172	0	0	0	0	111.2	V38 V39 M40 W45 A46 T203 L206	V38-V42 WeakPolarHBondContact O-CG2 3.49Å; V38-V42 PolarHBondContact O-N 3.26Å; V39-V42 PolarHBondContact O-N 3.19Å; M40-V42 PolarHBondContact O-N 2.94Å; V42-W45 PolarHBondContact O-N 2.79Å; V42-A46 WeakPolarHBondContact O-CB 3.43Å; V42-A46 PolarHBondContact O-N 2.81Å; V42-T203 HydrophobicContact CB-CG2 4.46Å; V42-T203 HydrophobicContact CG1-CG2 4.16Å; V42-L206 HydrophobicContact CG2-CD2 4.12Å
43	G	76.3	Confident	76.5	Confident	3 Å²	3	63.7 Å²	63.7	3%	0.031	32%	0.324	C	S	.	.	H	α-helix	trans	-59.8	-46.3	176.5	0	0	0	0	0	112.4	V39 M40 M47 S199	V39-G43 PolarHBondContact O-N 3.29Å; M40-G43 PolarHBondContact O-N 2.93Å; G43-M47 VanDerWaalsContact O-CB 3.3Å; G43-M47 WeakPolarHBondContact O-CB 3.48Å; G43-M47 PolarHBondContact O-N 3.17Å; G43-S199 PolarHBondContact O-OG 3.22Å; G43-S199 VanDerWaalsContact O-OG 3.12Å
44	L	77.6	Confident	75.6	Confident	83 Å²	83	62.1 Å²	62.1	44%	0.435	32%	0.315	S	S	.	.	H	α-helix	trans	-65.6	-42.3	175.7	-71.7	172.8	0	0	0	112.1	M40 A41 M47 L48	M40-L44 HydrophobicContact CG-CD1 4.03Å; M40-L44 HydrophobicContact CG-CG 4.41Å; M40-L44 WeakPolarHBondContact O-CB 3.49Å; M40-L44 VanDerWaalsContact O-CG 3.28Å; M40-L44 WeakPolarHBondContact O-CG 3.15Å; M40-L44 PolarHBondContact O-N 3.05Å; A41-L44 PolarHBondContact O-N 2.97Å; L44-M47 HydrophobicContact CD2-CE 4.24Å; L44-M47 HydrophobicContact CD2-SD 4.48Å; L44-M47 WeakPolarHBondContact O-CB 3.18Å; L44-M47 PolarHBondContact O-N 3.12Å; L44-L48 WeakPolarHBondContact O-CG 3.46Å; L44-L48 PolarHBondContact O-N 2.89Å
45	W	82.8	Confident	74.2	Confident	140 Å²	140	59.3 Å²	59.3	53%	0.53	30%	0.3	S	S	.	.	H	α-helix	trans	-60.8	-46.7	176.7	174.3	81	0	0	0	111.8	A41 V42 M47 L48 R49	A41-W45 VanDerWaalsContact O-CB 3.26Å; A41-W45 WeakPolarHBondContact O-CB 3.42Å; A41-W45 PolarHBondContact O-N 2.83Å; V42-W45 PolarHBondContact O-N 2.79Å; W45-M47 VanDerWaalsContact C-N 3.3Å; W45-M47 PolarHBondContact O-N 3.44Å; W45-L48 PolarHBondContact O-N 3.37Å; W45-R49 PolarHBondContact O-N 3.22Å
46	A	75.7	Confident	72.9	Confident	1 Å²	1	60.2 Å²	60.2	1%	0.008	31%	0.313	C	S	.	.	H	α-helix	trans	-63	-38.9	175.6	0	0	0	0	0	111.7	V42 L48 R49 T50 Y202	V42-A46 WeakPolarHBondContact O-CB 3.43Å; V42-A46 PolarHBondContact O-N 2.81Å; A46-L48 VanDerWaalsContact C-N 3.34Å; A46-L48 PolarHBondContact O-N 2.93Å; A46-R49 PolarHBondContact O-N 3.07Å; A46-T50 PolarHBondContact O-N 3.4Å; A46-T50 PolarHBondContact O-OG1 3.41Å; A46-Y202 HydrophobicContact CB-CD2 3.8Å; A46-Y202 HydrophobicContact CB-CG 4.37Å
47	M	70.4	Confident	71.7	Confident	20 Å²	20	57.9 Å²	57.9	10%	0.099	31%	0.305	C	S	.	.	H	α-helix	trans	-60.9	-40.9	177.1	-174.4	-168.5	-60.8	0	0	112.5	G43 L44 W45 R49 R52 T194	G43-M47 VanDerWaalsContact O-CB 3.3Å; G43-M47 WeakPolarHBondContact O-CB 3.48Å; G43-M47 PolarHBondContact O-N 3.17Å; L44-M47 HydrophobicContact CD2-CE 4.24Å; L44-M47 HydrophobicContact CD2-SD 4.48Å; L44-M47 WeakPolarHBondContact O-CB 3.18Å; L44-M47 PolarHBondContact O-N 3.12Å; W45-M47 VanDerWaalsContact C-N 3.3Å; W45-M47 PolarHBondContact O-N 3.44Å; M47-R49 VanDerWaalsContact C-N 3.33Å; M47-R52 VanDerWaalsContact CG-NE 3.34Å; M47-R52 PolarHBondContact SD-NH1 3.15Å; M47-R52 VanDerWaalsContact SD-NH1 3.44Å; M47-T194 WeakPolarHBondContact CE-O 3.43Å
48	L	71.4	Confident	70.5	Confident	132 Å²	132	53.9 Å²	53.9	69%	0.691	28%	0.284	S	S	*	.	H	α-helix	trans	-73.2	-25.2	180	-68.7	172.3	0	0	0	113.1	L44 W45 A46	L44-L48 WeakPolarHBondContact O-CG 3.46Å; L44-L48 PolarHBondContact O-N 2.89Å; W45-L48 PolarHBondContact O-N 3.37Å; A46-L48 VanDerWaalsContact C-N 3.34Å; A46-L48 PolarHBondContact O-N 2.93Å
49	R	70.3	Confident	69.2	Low	193 Å²	193	50.8 Å²	50.8	73%	0.728	27%	0.265	S	S	*	.	H	α-helix	trans	-86.9	-16.1	-177.3	-141.5	-164.1	-170.2	-145.7	4.6	114.1	W45 A46 M47	W45-R49 PolarHBondContact O-N 3.22Å; A46-R49 PolarHBondContact O-N 3.07Å; M47-R49 VanDerWaalsContact C-N 3.33Å
50	T	64.8	Low	68.4	Low	34 Å²	34	50.8 Å²	50.8	21%	0.209	26%	0.264	C	S	.	.	S	Bend	trans	-108.3	131.3	-171.2	-36.6	0	0	0	0	110.6	A46 R52 A198	A46-T50 PolarHBondContact O-N 3.4Å; A46-T50 PolarHBondContact O-OG1 3.41Å; T50-R52 PolarHBondContact O-N 3.42Å; T50-R52 VanDerWaalsContact O-N 3.09Å; T50-A198 HydrophobicContact CG2-CB 3.8Å
51	N	62.5	Low	67.8	Low	79 Å²	79	46.5 Å²	46.5	42%	0.422	24%	0.244	S	C	.	.			trans	-73.6	102.4	174.4	-168.9	-2.3	0	0	0	109.7	G53 G57	N51-G53 PolarHBondContact OD1-N 3.43Å; N51-G57 VanDerWaalsContact O-CA 3.32Å; N51-G57 WeakPolarHBondContact O-CA 3.5Å
52	R	62.3	Low	66.9	Low	18 Å²	18	46.3 Å²	46.3	7%	0.068	25%	0.248	C	C	.	.			trans	-88.6	-1.6	-177.8	-68.3	-178.7	-68.9	145.4	8.4	113.9	M47 T50 T54 T194 L605 F606	M47-R52 VanDerWaalsContact CG-NE 3.34Å; M47-R52 PolarHBondContact SD-NH1 3.15Å; M47-R52 VanDerWaalsContact SD-NH1 3.44Å; T50-R52 PolarHBondContact O-N 3.42Å; T50-R52 VanDerWaalsContact O-N 3.09Å; R52-T54 PolarHBondContact O-N 3.24Å; R52-T194 PolarHBondContact NH1-O 2.68Å; R52-L605 PolarHBondContact NH2-O 3.49Å; R52-F606 PolarHBondContact NH1-O 3.5Å; R52-F606 VanDerWaalsContact NH1-O 3.17Å
53	G	57.5	Low	66.5	Low	6 Å²	6	46.2 Å²	46.2	6%	0.062	24%	0.244	C	C	.	.	S	Bend	trans	-73.9	-5.7	-173.6	0	0	0	0	0	115.9	N51 Q610	N51-G53 PolarHBondContact OD1-N 3.43Å; G53-Q610 WeakPolarHBondContact CA-O 3.43Å
54	T	63.6	Low	66.7	Low	44 Å²	44	51 Å²	51	27%	0.27	27%	0.268	S	S	.	.	S	Bend	trans	-125.9	154.5	-178.6	66.8	0	0	0	0	110.9	R52 G56 G57 F58	R52-T54 PolarHBondContact O-N 3.24Å; T54-G56 VanDerWaalsContact C-N 3.3Å; T54-G56 PolarHBondContact O-N 3.49Å; T54-G57 PolarHBondContact O-N 3.14Å; T54-G57 VanDerWaalsContact O-N 3.08Å; T54-G57 PolarHBondContact OG1-N 2.84Å; T54-F58 PolarHBondContact O-N 3.43Å
55	I	59	Low	67.2	Low	46 Å²	46	47.2 Å²	47.2	24%	0.236	25%	0.249	C	C	.	.	H	α-helix	trans	-54.7	-45.8	177.5	-64	176.8	0	0	0	110.7	G57 F58 F59 I407 E419	I55-G57 PolarHBondContact O-N 3.17Å; I55-F58 PolarHBondContact O-N 2.63Å; I55-F59 HydrophobicContact CB-CD2 4.41Å; I55-F59 HydrophobicContact CG2-CD2 3.64Å; I55-F59 HydrophobicContact CG2-CE2 4.13Å; I55-F59 WeakPolarHBondContact O-CB 3.32Å; I55-F59 WeakPolarHBondContact O-CD2 3.39Å; I55-F59 PolarHBondContact O-N 3.2Å; I55-I407 HydrophobicContact CG2-CD1 4.4Å; I55-E419 HydrophobicContact CD1-CG 4.3Å
56	G	58.7	Low	67.6	Low	31 Å²	31	41.9 Å²	41.9	32%	0.32	24%	0.235	S	C	.	.	H	α-helix	trans	-66.8	-32.5	177.7	0	0	0	0	0	114.1	T54 L60 A61 G62	T54-G56 VanDerWaalsContact C-N 3.3Å; T54-G56 PolarHBondContact O-N 3.49Å; G56-L60 CarbonylContact O-C 3.56Å; G56-L60 WeakPolarHBondContact O-CA 3.21Å; G56-L60 VanDerWaalsContact O-CB 3.31Å; G56-L60 WeakPolarHBondContact O-CB 3.49Å; G56-L60 PolarHBondContact O-N 3.15Å; G56-A61 PolarHBondContact O-N 3.36Å; G56-G62 PolarHBondContact O-N 3.36Å
57	G	57.6	Low	68.5	Low	7 Å²	7	47.1 Å²	47.1	7%	0.072	25%	0.254	C	S	.	.	H	α-helix	trans	-69.9	-43.5	175.2	0	0	0	0	0	112.7	N51 T54 I55 A61	N51-G57 VanDerWaalsContact O-CA 3.32Å; N51-G57 WeakPolarHBondContact O-CA 3.5Å; T54-G57 PolarHBondContact O-N 3.14Å; T54-G57 VanDerWaalsContact O-N 3.08Å; T54-G57 PolarHBondContact OG1-N 2.84Å; I55-G57 PolarHBondContact O-N 3.17Å; G57-A61 PolarHBondContact O-N 2.68Å
58	F	59.7	Low	69.7	Low	10 Å²	10	52 Å²	52	4%	0.044	27%	0.272	C	S	.	.	H	α-helix	trans	-74.1	-47.6	180	-172.4	-96.9	0	0	0	112.7	T54 I55 G195 L197 L423	T54-F58 PolarHBondContact O-N 3.43Å; I55-F58 PolarHBondContact O-N 2.63Å; F58-G195 WeakPolarHBondContact CE2-O 3.49Å; F58-L197 WeakPolarHBondContact O-CB 3.41Å; F58-L197 PolarHBondContact O-N 3.19Å; F58-L423 HydrophobicContact CB-CD2 4.32Å; F58-L423 HydrophobicContact CD1-CD2 4.05Å; F58-L423 HydrophobicContact CG-CD2 4.14Å
59	F	59.3	Low	70.7	Confident	4 Å²	4	45.8 Å²	45.8	2%	0.018	24%	0.239	C	C	.	.	H	α-helix	trans	-94.4	-21.2	-172.7	-65	-65.1	0	0	0	115.5	I55 L197 Q299 T403 I407 L423	I55-F59 HydrophobicContact CB-CD2 4.41Å; I55-F59 HydrophobicContact CG2-CD2 3.64Å; I55-F59 HydrophobicContact CG2-CE2 4.13Å; I55-F59 WeakPolarHBondContact O-CB 3.32Å; I55-F59 WeakPolarHBondContact O-CD2 3.39Å; I55-F59 PolarHBondContact O-N 3.2Å; F59-L197 WeakPolarHBondContact O-CD2 3.18Å; F59-Q299 PolarHBondContact O-NE2 2.94Å; F59-T403 HydrophobicContact CD1-CG2 3.86Å; F59-T403 WeakPolarHBondContact CD1-OG1 3.47Å; F59-T403 HydrophobicContact CE1-CG2 4.09Å; F59-T403 WeakPolarHBondContact CE1-OG1 3.43Å; F59-T403 HydrophobicContact CG-CG2 4.21Å; F59-I407 HydrophobicContact CD2-CD1 4.3Å; F59-I407 HydrophobicContact CE2-CD1 4.36Å; F59-L423 HydrophobicContact CE2-CD2 4.2Å; F59-L423 HydrophobicContact CZ-CD2 4.49Å
60	L	63.4	Low	71.8	Confident	20 Å²	20	36.6 Å²	36.6	11%	0.105	20%	0.204	C	C	.	.	H	α-helix	trans	-120.7	6.4	-178.5	-67.1	177.3	0	0	0	113.7	G56 G62 R63 T126 L302 S303	G56-L60 CarbonylContact O-C 3.56Å; G56-L60 WeakPolarHBondContact O-CA 3.21Å; G56-L60 VanDerWaalsContact O-CB 3.31Å; G56-L60 WeakPolarHBondContact O-CB 3.49Å; G56-L60 PolarHBondContact O-N 3.15Å; L60-G62 PolarHBondContact O-N 3.28Å; L60-R63 HydrophobicContact CB-CG 4.25Å; L60-R63 PolarHBondContact O-N 2.69Å; L60-R63 VanDerWaalsContact O-N 3.08Å; L60-T126 HydrophobicContact CD1-CG2 4.08Å; L60-L302 HydrophobicContact CD2-CB 3.95Å; L60-S303 VanDerWaalsContact O-CB 3.29Å; L60-S303 WeakPolarHBondContact O-CB 3.18Å
61	A	66.8	Low	73.3	Confident	10 Å²	10	35 Å²	35	8%	0.083	19%	0.194	C	C	.	.	G	3₁₀ helix	trans	52.3	27.4	-176.6	0	0	0	0	0	113.4	G56 G57 R63 V65 A198	G56-A61 PolarHBondContact O-N 3.36Å; G57-A61 PolarHBondContact O-N 2.68Å; A61-R63 PolarHBondContact O-N 2.81Å; A61-R63 VanDerWaalsContact O-N 3.16Å; A61-V65 HydrophobicContact CB-CG2 3.98Å; A61-A198 HydrophobicContact CB-CB 3.71Å
62	G	64.1	Low	74.8	Confident	53 Å²	53	31.6 Å²	31.6	55%	0.546	18%	0.177	S	C	.	.	G	3₁₀ helix	trans	66.2	9.9	-178.5	0	0	0	0	0	116	G56 L60 D64	G56-G62 PolarHBondContact O-N 3.36Å; L60-G62 PolarHBondContact O-N 3.28Å; G62-D64 PolarHBondContact O-N 3.48Å
63	R	73.4	Confident	76.3	Confident	37 Å²	37	30.7 Å²	30.7	14%	0.14	17%	0.174	C	C	.	.	G	3₁₀ helix	trans	52.7	45.6	-179.4	-54.5	-173.4	81	-177.4	-14.5	115.2	L60 A61 L302 S303 K305 L627	L60-R63 HydrophobicContact CB-CG 4.25Å; L60-R63 PolarHBondContact O-N 2.69Å; L60-R63 VanDerWaalsContact O-N 3.08Å; A61-R63 PolarHBondContact O-N 2.81Å; A61-R63 VanDerWaalsContact O-N 3.16Å; R63-L302 WeakPolarHBondContact CD-O 3.29Å; R63-L302 WeakPolarHBondContact CG-O 3.24Å; R63-L302 PolarHBondContact NE-O 3.18Å; R63-S303 CarbonylContact C-O 3.53Å; R63-S303 VanDerWaalsContact CA-O 3.26Å; R63-S303 WeakPolarHBondContact CA-O 3.48Å; R63-K305 WeakPolarHBondContact O-CA 3.25Å; R63-L627 HydrophobicContact CB-CD2 4.32Å; R63-L627 HydrophobicContact CG-CD2 4.14Å; R63-L627 VanDerWaalsContact CZ-O 3.26Å; R63-L627 PolarHBondContact NH1-O 2.9Å; R63-L627 PolarHBondContact NH2-O 2.94Å
64	D	80.8	Confident	78	Confident	103 Å²	103	30.4 Å²	30.4	55%	0.551	17%	0.171	S	C	*	.			trans	-125.7	24.5	175.4	-165.3	34.7	0	0	0	112.1	G62 K305	G62-D64 PolarHBondContact O-N 3.48Å; D64-K305 WeakPolarHBondContact OD1-CD 3.27Å; D64-K305 WeakPolarHBondContact OD1-CE 3.32Å; D64-K305 IonicContact OD1-NZ 3.3Å; D64-K305 PolarHBondContact OD1-NZ 3.43Å
65	V	86.3	Confident	79.5	Confident	4 Å²	4	28.4 Å²	28.4	2%	0.024	16%	0.158	C	C	.	.	B	Isolated β-bridge	trans	-81.6	130.4	-178	-172	0	0	0	0	110.3	A61 P69 M70 I201 S303 K305	A61-V65 HydrophobicContact CB-CG2 3.98Å; V65-P69 HydrophobicContact CG1-CB 4.38Å; V65-M70 HydrophobicContact CG1-CB 3.96Å; V65-I201 HydrophobicContact CG1-CD1 4.39Å; V65-I201 HydrophobicContact CG1-CG2 3.96Å; V65-I201 HydrophobicContact CG2-CD1 4.06Å; V65-S303 WeakPolarHBondContact CB-O 3.25Å; V65-S303 WeakPolarHBondContact CG2-O 3.49Å; V65-S303 PolarHBondContact N-O 3.18Å; V65-K305 PolarHBondContact O-N 2.97Å
66	A	92.4	Very high	81	Confident	28 Å²	28	26.2 Å²	26.2	23%	0.231	15%	0.147	C	C	.	.			trans	-70.7	168.1	175.4	0	0	0	0	0	112.1	W68 P69 M70	A66-W68 PolarHBondContact O-N 3.37Å; A66-P69 HydrophobicContact CB-CG 4.49Å; A66-P69 WeakPolarHBondContact O-CD 3.47Å; A66-M70 WeakPolarHBondContact O-CB 3.16Å; A66-M70 WeakPolarHBondContact O-CE 3.33Å; A66-M70 PolarHBondContact O-N 2.78Å
67	W	94.8	Very high	82.4	Confident	110 Å²	110	25.3 Å²	25.3	42%	0.417	14%	0.136	S	C	.	.	H	α-helix	trans	-68.9	-35.2	-174.2	64.6	-93.7	0	0	0	113.1	G71 H309 A312 A313 M316	W67-G71 PolarHBondContact O-N 3.47Å; W67-H309 HydrophobicContact CB-CB 4.26Å; W67-H309 WeakPolarHBondContact CB-O 3.41Å; W67-H309 AromaticContact CD1-CE1 3.83Å; W67-H309 AromaticContact CD1-ND1 3.75Å; W67-H309 PolarHBondContact N-ND1 3.45Å; W67-H309 VanDerWaalsContact N-ND1 3.11Å; W67-A312 HydrophobicContact CB-CB 3.69Å; W67-A312 HydrophobicContact CD2-CB 4.27Å; W67-A312 HydrophobicContact CE3-CB 4.4Å; W67-A312 HydrophobicContact CG-CB 3.97Å; W67-A313 HydrophobicContact CB-CB 4.49Å; W67-A313 WeakPolarHBondContact O-CA 3.25Å; W67-A313 VanDerWaalsContact O-CB 3.3Å; W67-A313 WeakPolarHBondContact O-CB 3.45Å; W67-M316 HydrophobicContact CE3-CB 4.28Å; W67-M316 HydrophobicContact CE3-SD 3.93Å; W67-M316 HydrophobicContact CH2-SD 4.39Å; W67-M316 HydrophobicContact CZ3-CB 4.11Å; W67-M316 HydrophobicContact CZ3-CG 4.04Å; W67-M316 HydrophobicContact CZ3-SD 3.43Å; W67-M316 WeakPolarHBondContact CZ3-SD 3.36Å
68	W	94.6	Very high	84	Confident	124 Å²	124	25.8 Å²	25.8	47%	0.47	14%	0.137	S	C	.	.	H	α-helix	trans	-75.4	-44.3	-174.4	67	-88.1	0	0	0	113.6	A66 M70 G71 A72 T205 M316	A66-W68 PolarHBondContact O-N 3.37Å; W68-M70 VanDerWaalsContact C-N 3.3Å; W68-M70 PolarHBondContact O-N 2.9Å; W68-G71 PolarHBondContact O-N 3.19Å; W68-A72 WeakPolarHBondContact O-CB 3.47Å; W68-A72 PolarHBondContact O-N 2.79Å; W68-T205 HydrophobicContact CE3-CG2 3.73Å; W68-T205 HydrophobicContact CH2-CG2 4.39Å; W68-T205 HydrophobicContact CZ3-CG2 3.36Å; W68-M316 HydrophobicContact CB-SD 4.23Å; W68-M316 WeakPolarHBondContact O-CE 3.36Å
69	P	93.5	Very high	85.4	Confident	1 Å²	1	25.3 Å²	25.3	1%	0.006	14%	0.135	C	C	.	.	H	α-helix	trans	-69.1	-35.3	175.4	-16	33.8	0	0	0	110.8	V65 A66 A72 S73 I201 Y202 T205	V65-P69 HydrophobicContact CG1-CB 4.38Å; A66-P69 HydrophobicContact CB-CG 4.49Å; A66-P69 WeakPolarHBondContact O-CD 3.47Å; P69-A72 PolarHBondContact O-N 3.3Å; P69-S73 VanDerWaalsContact O-CB 3.27Å; P69-S73 WeakPolarHBondContact O-CB 3.42Å; P69-S73 PolarHBondContact O-N 3Å; P69-I201 HydrophobicContact CB-CG2 3.83Å; P69-Y202 HydrophobicContact CB-CE1 4.48Å; P69-Y202 HydrophobicContact CG-CE1 4.38Å; P69-T205 WeakPolarHBondContact CA-OG1 3.41Å; P69-T205 HydrophobicContact CB-CG2 4.3Å; P69-T205 WeakPolarHBondContact CB-OG1 3.47Å; P69-T205 PolarHBondContact O-OG1 3.3Å
70	M	93.7	Very high	86.7	Confident	0 Å²	0	25.1 Å²	25.1	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-62.4	-49.1	176.9	-170.2	-168.1	-26.7	0	0	111.5	V65 A66 W68 A72 S73 L74 H309 V310 A313	V65-M70 HydrophobicContact CG1-CB 3.96Å; A66-M70 WeakPolarHBondContact O-CB 3.16Å; A66-M70 WeakPolarHBondContact O-CE 3.33Å; A66-M70 PolarHBondContact O-N 2.78Å; W68-M70 VanDerWaalsContact C-N 3.3Å; W68-M70 PolarHBondContact O-N 2.9Å; M70-A72 VanDerWaalsContact C-N 3.34Å; M70-A72 PolarHBondContact O-N 3.32Å; M70-S73 PolarHBondContact O-N 3.42Å; M70-L74 WeakPolarHBondContact O-CG 3.43Å; M70-L74 PolarHBondContact O-N 2.95Å; M70-H309 HydrophobicContact CE-CB 4.48Å; M70-V310 HydrophobicContact CE-CG2 4.31Å; M70-V310 HydrophobicContact SD-CB 4.49Å; M70-V310 HydrophobicContact SD-CG2 4.15Å; M70-A313 HydrophobicContact CB-CB 3.86Å; M70-A313 HydrophobicContact CE-CB 4.11Å; M70-A313 HydrophobicContact CG-CB 3.84Å; M70-A313 HydrophobicContact SD-CB 3.58Å; M70-A313 VanDerWaalsContact SD-CB 3.58Å
71	G	95.7	Very high	87.7	Confident	0 Å²	0	24.2 Å²	24.2	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-68.3	-32.8	179.1	0	0	0	0	0	113	W67 W68 L74 F75 A313	W67-G71 PolarHBondContact O-N 3.47Å; W68-G71 PolarHBondContact O-N 3.19Å; G71-L74 PolarHBondContact O-N 2.87Å; G71-F75 WeakPolarHBondContact O-CB 3.32Å; G71-F75 PolarHBondContact O-N 3.36Å; G71-A313 WeakPolarHBondContact CA-O 3.43Å
72	A	94.6	Very high	88.7	Confident	7 Å²	7	24.1 Å²	24.1	6%	0.058	13%	0.127	C	C	.	.	H	α-helix	trans	-68.2	-42.3	174.3	0	0	0	0	0	110.6	W68 P69 M70 F75 A76 T205 T208 M316	W68-A72 WeakPolarHBondContact O-CB 3.47Å; W68-A72 PolarHBondContact O-N 2.79Å; P69-A72 PolarHBondContact O-N 3.3Å; M70-A72 VanDerWaalsContact C-N 3.34Å; M70-A72 PolarHBondContact O-N 3.32Å; A72-F75 WeakPolarHBondContact O-CB 3.25Å; A72-F75 PolarHBondContact O-N 2.63Å; A72-A76 WeakPolarHBondContact O-CB 3.22Å; A72-A76 PolarHBondContact O-N 3.48Å; A72-T205 HydrophobicContact CB-CG2 3.97Å; A72-T208 HydrophobicContact CB-CG2 4.2Å; A72-T208 PolarHBondContact O-OG1 2.9Å; A72-M316 HydrophobicContact CB-CE 4.16Å
73	S	92.3	Very high	90	Very high	0 Å²	0	22.3 Å²	22.3	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-66.6	-38	174.7	-176.1	0	0	0	0	112.5	P69 M70 F75 A76 S77 D204 R300	P69-S73 VanDerWaalsContact O-CB 3.27Å; P69-S73 WeakPolarHBondContact O-CB 3.42Å; P69-S73 PolarHBondContact O-N 3Å; M70-S73 PolarHBondContact O-N 3.42Å; S73-F75 VanDerWaalsContact C-N 3.29Å; S73-F75 PolarHBondContact O-N 3.02Å; S73-A76 PolarHBondContact O-N 3.27Å; S73-S77 VanDerWaalsContact O-CB 3.25Å; S73-S77 WeakPolarHBondContact O-CB 3.27Å; S73-S77 PolarHBondContact O-N 3.13Å; S73-S77 PolarHBondContact O-OG 3.49Å; S73-D204 PolarHBondContact OG-OD2 2.86Å; S73-R300 PolarHBondContact OG-NE 2.92Å
74	L	93.7	Very high	90.9	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-57.6	-43.4	170.4	-75.3	171.6	0	0	0	111.3	M70 G71 I297 R300 A313 C317	M70-L74 WeakPolarHBondContact O-CG 3.43Å; M70-L74 PolarHBondContact O-N 2.95Å; G71-L74 PolarHBondContact O-N 2.87Å; L74-I297 HydrophobicContact CD2-CG2 3.83Å; L74-R300 HydrophobicContact CD2-CB 3.92Å; L74-R300 HydrophobicContact CG-CB 4.43Å; L74-A313 HydrophobicContact CD1-CB 4.34Å; L74-C317 HydrophobicContact CB-CB 4.09Å
75	F	94.4	Very high	91.4	Very high	2 Å²	2	15.7 Å²	15.7	1%	0.009	7%	0.072	C	C	.	.	H	α-helix	trans	-66.4	-52.4	177.2	177	-100.6	0	0	0	112	G71 A72 S73 S77 N78 I79 T208 M211 L212 L320 K321	G71-F75 WeakPolarHBondContact O-CB 3.32Å; G71-F75 PolarHBondContact O-N 3.36Å; A72-F75 WeakPolarHBondContact O-CB 3.25Å; A72-F75 PolarHBondContact O-N 2.63Å; S73-F75 VanDerWaalsContact C-N 3.29Å; S73-F75 PolarHBondContact O-N 3.02Å; F75-S77 VanDerWaalsContact C-N 3.28Å; F75-S77 PolarHBondContact O-N 3.5Å; F75-N78 PolarHBondContact O-N 2.96Å; F75-N78 VanDerWaalsContact O-N 3.14Å; F75-I79 HydrophobicContact CD1-CB 4.4Å; F75-I79 HydrophobicContact CD2-CG1 3.85Å; F75-I79 HydrophobicContact CE1-CB 4.07Å; F75-I79 HydrophobicContact CE1-CG1 4.18Å; F75-I79 HydrophobicContact CE1-CG2 4.2Å; F75-I79 HydrophobicContact CE2-CB 4.22Å; F75-I79 HydrophobicContact CE2-CG1 3.42Å; F75-I79 VanDerWaalsContact CE2-CG1 3.42Å; F75-I79 HydrophobicContact CG-CG1 4.4Å; F75-I79 HydrophobicContact CZ-CB 3.97Å; F75-I79 HydrophobicContact CZ-CG1 3.62Å; F75-I79 HydrophobicContact CZ-CG2 4.05Å; F75-I79 WeakPolarHBondContact O-CB 3.49Å; F75-I79 PolarHBondContact O-N 3.49Å; F75-T208 HydrophobicContact CD1-CG2 3.59Å; F75-T208 HydrophobicContact CE1-CG2 4.04Å; F75-M211 HydrophobicContact CD1-CE 4.09Å; F75-M211 HydrophobicContact CE1-CE 3.46Å; F75-M211 VanDerWaalsContact CE1-CE 3.46Å; F75-M211 HydrophobicContact CZ-CE 4.37Å; F75-L212 HydrophobicContact CE1-CD2 4.08Å; F75-L212 HydrophobicContact CE1-CG 4.5Å; F75-L212 HydrophobicContact CZ-CD2 4.09Å; F75-L320 HydrophobicContact CB-CB 4.5Å; F75-L320 HydrophobicContact CB-CD1 3.94Å; F75-L320 HydrophobicContact CD1-CD1 4.21Å; F75-L320 HydrophobicContact CD2-CB 3.47Å; F75-L320 VanDerWaalsContact CD2-CB 3.47Å; F75-L320 HydrophobicContact CD2-CD1 4.31Å; F75-L320 HydrophobicContact CE2-CB 3.67Å; F75-L320 WeakPolarHBondContact CE2-O 3.01Å; F75-L320 HydrophobicContact CG-CB 3.95Å; F75-L320 HydrophobicContact CG-CD1 3.91Å; F75-L320 HydrophobicContact CZ-CB 4.31Å; F75-K321 HydrophobicContact CD2-CD 4.48Å; F75-K321 HydrophobicContact CD2-CG 4.5Å
76	A	91.4	Very high	91.6	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-62.7	-31.5	180	0	0	0	0	0	113.8	A72 S73 N78 I79 D204 T208	A72-A76 WeakPolarHBondContact O-CB 3.22Å; A72-A76 PolarHBondContact O-N 3.48Å; S73-A76 PolarHBondContact O-N 3.27Å; A76-N78 PolarHBondContact O-N 3.36Å; A76-I79 CarbonylContact O-C 3.55Å; A76-D204 HydrophobicContact CB-CB 3.9Å; A76-T208 WeakPolarHBondContact CB-OG1 3.44Å
77	S	88.1	Confident	91.7	Very high	11 Å²	11	14.2 Å²	14.2	8%	0.077	6%	0.06	C	C	.	.	H	α-helix	trans	-67.6	-23.1	178.1	-60.5	0	0	0	0	112.9	S73 F75 R300	S73-S77 VanDerWaalsContact O-CB 3.25Å; S73-S77 WeakPolarHBondContact O-CB 3.27Å; S73-S77 PolarHBondContact O-N 3.13Å; S73-S77 PolarHBondContact O-OG 3.49Å; F75-S77 VanDerWaalsContact C-N 3.28Å; F75-S77 PolarHBondContact O-N 3.5Å; S77-R300 PolarHBondContact OG-NE 3.4Å; S77-R300 PolarHBondContact OG-NH1 2.95Å; S77-R300 PolarHBondContact OG-NH2 2.96Å
78	N	90.3	Very high	91.7	Very high	18 Å²	18	9 Å²	9	10%	0.096	4%	0.04	C	C	.	.	H	α-helix	trans	-101.6	-51.3	174.2	-174.9	-142.4	0	0	0	110.9	F75 A76 G80 H83 Y290 W291 K321	F75-N78 PolarHBondContact O-N 2.96Å; F75-N78 VanDerWaalsContact O-N 3.14Å; A76-N78 PolarHBondContact O-N 3.36Å; N78-G80 PolarHBondContact O-N 3.32Å; N78-H83 PolarHBondContact ND2-NE2 3.5Å; N78-H83 PolarHBondContact O-CE1 3.39Å; N78-H83 PolarHBondContact O-ND1 3.2Å; N78-H83 PolarHBondContact O-NE2 2.88Å; N78-Y290 HydrophobicContact CB-CE1 4.03Å; N78-Y290 VanDerWaalsContact CB-OH 3.32Å; N78-Y290 WeakPolarHBondContact CB-OH 3.45Å; N78-Y290 PolarHBondContact ND2-OH 2.99Å; N78-W291 HydrophobicContact CB-CH2 3.92Å; N78-W291 HydrophobicContact CB-CZ2 4.26Å; N78-W291 VanDerWaalsContact OD1-CZ2 3.26Å; N78-W291 WeakPolarHBondContact OD1-CZ2 3.28Å; N78-K321 VanDerWaalsContact OD1-CE 3.29Å; N78-K321 WeakPolarHBondContact OD1-CE 3.41Å; N78-K321 PolarHBondContact OD1-NZ 2.8Å
79	I	90.1	Very high	91.7	Very high	0 Å²	0	3 Å²	3	0%	0	2%	0.017	C	C	.	.	S	Bend	trans	-76.4	89.1	175.3	-60	-55.5	0	0	0	110.6	F75 A76 H83 Y84 E102 M211 K321 P324 M328	F75-I79 HydrophobicContact CD1-CB 4.4Å; F75-I79 HydrophobicContact CD2-CG1 3.85Å; F75-I79 HydrophobicContact CE1-CB 4.07Å; F75-I79 HydrophobicContact CE1-CG1 4.18Å; F75-I79 HydrophobicContact CE1-CG2 4.2Å; F75-I79 HydrophobicContact CE2-CB 4.22Å; F75-I79 HydrophobicContact CE2-CG1 3.42Å; F75-I79 VanDerWaalsContact CE2-CG1 3.42Å; F75-I79 HydrophobicContact CG-CG1 4.4Å; F75-I79 HydrophobicContact CZ-CB 3.97Å; F75-I79 HydrophobicContact CZ-CG1 3.62Å; F75-I79 HydrophobicContact CZ-CG2 4.05Å; F75-I79 WeakPolarHBondContact O-CB 3.49Å; F75-I79 PolarHBondContact O-N 3.49Å; A76-I79 CarbonylContact O-C 3.55Å; I79-H83 HydrophobicContact CD1-CB 4.03Å; I79-Y84 HydrophobicContact CG2-CE2 4.13Å; I79-E102 WeakPolarHBondContact CD1-OE2 3.42Å; I79-M211 HydrophobicContact CB-CE 4.25Å; I79-M211 HydrophobicContact CG2-CE 3.65Å; I79-M211 HydrophobicContact CG2-SD 4.37Å; I79-K321 VanDerWaalsContact CG1-NZ 3.32Å; I79-P324 HydrophobicContact CD1-CG 4.24Å; I79-M328 HydrophobicContact CG2-CE 3.29Å
80	G	86.5	Confident	91.8	Very high	0 Å²	0	3 Å²	3	0%	0	2%	0.017	C	C	.	.	S	Bend	trans	-110.7	-168.7	170	0	0	0	0	0	112.9	N78 N82 H83 Y84 S393	N78-G80 PolarHBondContact O-N 3.32Å; G80-N82 PolarHBondContact O-N 2.96Å; G80-H83 PolarHBondContact O-N 2.77Å; G80-Y84 WeakPolarHBondContact O-CD2 3.34Å; G80-Y84 PolarHBondContact O-N 2.91Å; G80-S393 WeakPolarHBondContact CA-OG 3.45Å
81	S	84.7	Confident	91.9	Very high	0 Å²	0	3 Å²	3	0%	0	2%	0.017	C	C	.	.	H	α-helix	trans	-56.8	-34.7	177	68.2	0	0	0	0	113.2	H83 Y84 V85 L390	S81-H83 VanDerWaalsContact C-N 3.26Å; S81-H83 PolarHBondContact O-N 2.86Å; S81-Y84 PolarHBondContact O-N 3.48Å; S81-V85 WeakPolarHBondContact O-CG2 2.94Å; S81-V85 PolarHBondContact O-N 3.37Å; S81-L390 VanDerWaalsContact OG-CD1 3.29Å; S81-L390 WeakPolarHBondContact OG-CD1 3.5Å
82	N	87.8	Confident	91.9	Very high	8 Å²	8	3 Å²	3	4%	0.043	2%	0.018	C	C	.	.	H	α-helix	trans	-53.3	-41.6	172.9	169.3	29.9	0	0	0	112.4	G80 V85 G86 S160 D161 A164 L452	G80-N82 PolarHBondContact O-N 2.96Å; N82-V85 PolarHBondContact O-N 3.31Å; N82-G86 VanDerWaalsContact O-CA 3.29Å; N82-G86 WeakPolarHBondContact O-CA 3.38Å; N82-G86 PolarHBondContact O-N 2.88Å; N82-S160 PolarHBondContact ND2-OG 3.29Å; N82-S160 VanDerWaalsContact ND2-OG 3.17Å; N82-S160 PolarHBondContact OD1-OG 3.39Å; N82-S160 VanDerWaalsContact OD1-OG 3.11Å; N82-D161 WeakPolarHBondContact CB-OD1 3.28Å; N82-A164 VanDerWaalsContact CA-CB 3.41Å; N82-A164 HydrophobicContact CB-CB 4.11Å; N82-L452 HydrophobicContact CB-CD2 4.38Å; N82-L452 WeakPolarHBondContact OD1-CD2 3.33Å; N82-L452 WeakPolarHBondContact OD1-CG 3.4Å
83	H	92	Very high	91.8	Very high	16 Å²	16	4 Å²	4	7%	0.074	3%	0.025	C	C	.	.	H	α-helix	trans	-72.9	-37	-178.4	-69.1	62.9	0	0	0	111.4	N78 I79 G80 S81 L87 E102 M328	N78-H83 PolarHBondContact ND2-NE2 3.5Å; N78-H83 PolarHBondContact O-CE1 3.39Å; N78-H83 PolarHBondContact O-ND1 3.2Å; N78-H83 PolarHBondContact O-NE2 2.88Å; I79-H83 HydrophobicContact CD1-CB 4.03Å; G80-H83 PolarHBondContact O-N 2.77Å; S81-H83 VanDerWaalsContact C-N 3.26Å; S81-H83 PolarHBondContact O-N 2.86Å; H83-L87 HydrophobicContact CB-CD1 4Å; H83-L87 HydrophobicContact CB-CG 4.35Å; H83-L87 WeakPolarHBondContact O-CA 3.25Å; H83-L87 WeakPolarHBondContact O-CB 3.26Å; H83-L87 PolarHBondContact O-N 3.46Å; H83-E102 IonicContact CD2-OE1 3.9Å; H83-E102 PolarHBondContact CD2-OE1 3.28Å; H83-E102 IonicContact NE2-OE1 2.9Å; H83-E102 PolarHBondContact NE2-OE1 2.86Å; H83-M328 HydrophobicContact CB-SD 4.12Å
84	Y	91.7	Very high	91.8	Very high	1 Å²	1	4.1 Å²	4.1	0%	0.004	3%	0.026	C	C	.	.	H	α-helix	trans	-65.1	-42.7	174.3	-79.8	-78.1	0	0	0	113.3	I79 G80 S81 A88 M211 S215 M328 Y366 M386	I79-Y84 HydrophobicContact CG2-CE2 4.13Å; G80-Y84 WeakPolarHBondContact O-CD2 3.34Å; G80-Y84 PolarHBondContact O-N 2.91Å; S81-Y84 PolarHBondContact O-N 3.48Å; Y84-A88 WeakPolarHBondContact O-CB 3.34Å; Y84-M211 HydrophobicContact CE2-CG 3.84Å; Y84-M211 HydrophobicContact CE2-SD 3.59Å; Y84-M211 VanDerWaalsContact CE2-SD 3.59Å; Y84-M211 WeakPolarHBondContact OH-CG 3.23Å; Y84-S215 WeakPolarHBondContact CE1-OG 3.37Å; Y84-S215 PolarHBondContact OH-OG 3.19Å; Y84-M328 HydrophobicContact CD1-CE 4.01Å; Y84-M328 HydrophobicContact CD1-CG 3.9Å; Y84-M328 HydrophobicContact CD1-SD 4.25Å; Y84-M328 HydrophobicContact CD2-CE 3.95Å; Y84-M328 HydrophobicContact CE1-CE 3.59Å; Y84-M328 HydrophobicContact CE1-CG 3.89Å; Y84-M328 HydrophobicContact CE1-SD 4.33Å; Y84-M328 HydrophobicContact CE2-CE 3.5Å; Y84-M328 VanDerWaalsContact CE2-CE 3.5Å; Y84-M328 HydrophobicContact CG-CE 4.19Å; Y84-M328 HydrophobicContact CG-SD 4.41Å; Y84-Y366 AromaticContact CD1-CD1 3.76Å; Y84-Y366 HydrophobicContact CD1-CD1 3.76Å; Y84-Y366 HydrophobicContact CD1-CD2 4.05Å; Y84-Y366 AromaticContact CD1-CE1 3.32Å; Y84-Y366 HydrophobicContact CD1-CE1 3.32Å; Y84-Y366 AromaticContact CD1-CE2 3.66Å; Y84-Y366 HydrophobicContact CD1-CE2 3.66Å; Y84-Y366 HydrophobicContact CD1-CG 4.1Å; Y84-Y366 AromaticContact CD1-CZ 3.26Å; Y84-Y366 AromaticContact CE1-CE1 3.8Å; Y84-Y366 HydrophobicContact CE1-CE1 3.8Å; Y84-Y366 AromaticContact CE1-CE2 3.99Å; Y84-Y366 HydrophobicContact CE1-CE2 3.99Å; Y84-Y366 AromaticContact CE1-CZ 3.41Å; Y84-Y366 VanDerWaalsContact CE1-CZ 3.41Å; Y84-Y366 VanDerWaalsContact CE1-OH 3.24Å; Y84-Y366 WeakPolarHBondContact CE1-OH 3.43Å; Y84-Y366 HydrophobicContact CG-CD1 4.38Å; Y84-Y366 HydrophobicContact CG-CE1 4.21Å; Y84-Y366 WeakPolarHBondContact O-CB 3.37Å; Y84-M386 HydrophobicContact CD1-CE 3.77Å; Y84-M386 HydrophobicContact CD2-CE 3.9Å; Y84-M386 HydrophobicContact CG-CE 3.36Å
85	V	90.6	Very high	91.9	Very high	0 Å²	0	4.1 Å²	4.1	0%	0	3%	0.026	C	C	.	.	H	α-helix	trans	-70.3	-52.6	175.6	173.5	0	0	0	0	110.2	S81 N82 G89 A164 I167 F168 N363 L452	S81-V85 WeakPolarHBondContact O-CG2 2.94Å; S81-V85 PolarHBondContact O-N 3.37Å; N82-V85 PolarHBondContact O-N 3.31Å; V85-G89 WeakPolarHBondContact O-CA 3.29Å; V85-G89 PolarHBondContact O-N 3.4Å; V85-A164 HydrophobicContact CB-CB 3.91Å; V85-A164 HydrophobicContact CG1-CB 4.33Å; V85-A164 HydrophobicContact CG2-CB 3.7Å; V85-I167 HydrophobicContact CG1-CD1 3.9Å; V85-F168 HydrophobicContact CG2-CD2 3.72Å; V85-F168 HydrophobicContact CG2-CE2 3.28Å; V85-F168 HydrophobicContact CG2-CZ 4.22Å; V85-N363 HydrophobicContact CG1-CB 3.6Å; V85-N363 WeakPolarHBondContact CG1-O 3.37Å; V85-L452 HydrophobicContact CB-CD2 4.39Å; V85-L452 HydrophobicContact CG1-CD2 4.11Å
86	G	91.1	Very high	92	Very high	0 Å²	0	4 Å²	4	0%	0	3%	0.026	C	C	.	.	H	α-helix	trans	-79.2	-47.3	-166.8	0	0	0	0	0	114.3	N82 G89 T90 I453	N82-G86 VanDerWaalsContact O-CA 3.29Å; N82-G86 WeakPolarHBondContact O-CA 3.38Å; N82-G86 PolarHBondContact O-N 2.88Å; G86-G89 PolarHBondContact O-N 3.36Å; G86-T90 VanDerWaalsContact O-CB 3.27Å; G86-T90 WeakPolarHBondContact O-CB 3.33Å; G86-T90 PolarHBondContact O-N 3.19Å; G86-T90 PolarHBondContact O-OG1 2.91Å; G86-I453 WeakPolarHBondContact O-CG1 3.32Å
87	L	94.4	Very high	92.2	Very high	0 Å²	0	4 Å²	4	0%	0	3%	0.026	C	C	.	.	H	α-helix	trans	-69.1	-40.2	178.6	-66.8	174.5	0	0	0	110.7	H83 G91 E102 P324 M328 V329 I453	H83-L87 HydrophobicContact CB-CD1 4Å; H83-L87 HydrophobicContact CB-CG 4.35Å; H83-L87 WeakPolarHBondContact O-CA 3.25Å; H83-L87 WeakPolarHBondContact O-CB 3.26Å; H83-L87 PolarHBondContact O-N 3.46Å; L87-G91 WeakPolarHBondContact O-CA 3.45Å; L87-G91 PolarHBondContact O-N 3.45Å; L87-E102 HydrophobicContact CD1-CG 3.62Å; L87-E102 HydrophobicContact CD2-CG 4.4Å; L87-P324 HydrophobicContact CD1-CB 4.17Å; L87-M328 HydrophobicContact CB-CB 4.4Å; L87-M328 HydrophobicContact CD1-SD 3.99Å; L87-V329 HydrophobicContact CB-CG2 4.3Å; L87-I453 HydrophobicContact CD2-CD1 4.06Å; L87-I453 HydrophobicContact CD2-CG1 4.05Å; L87-I453 HydrophobicContact CD2-CG2 4.43Å; L87-I453 HydrophobicContact CG-CD1 4.13Å; L87-I453 HydrophobicContact CG-CG1 4.32Å
88	A	95.4	Very high	92.5	Very high	0 Å²	0	3.5 Å²	3.5	0%	0	2%	0.022	C	C	.	.	H	α-helix	trans	-67.9	-40.2	175.7	0	0	0	0	0	111.5	Y84 G91 A92 M328 G332 Y366	Y84-A88 WeakPolarHBondContact O-CB 3.34Å; A88-G91 PolarHBondContact O-N 2.69Å; A88-A92 WeakPolarHBondContact O-CB 3.49Å; A88-A92 PolarHBondContact O-N 2.98Å; A88-M328 WeakPolarHBondContact CB-O 3.3Å; A88-G332 WeakPolarHBondContact O-CA 3.32Å; A88-Y366 HydrophobicContact CB-CD2 3.96Å; A88-Y366 HydrophobicContact CB-CG 4.24Å
89	G	94	Very high	92.7	Very high	0 Å²	0	2.7 Å²	2.7	0%	0	2%	0.018	C	C	.	.	H	α-helix	trans	-66.4	-42.8	176.4	0	0	0	0	0	112.8	V85 G86 G91 A92 A93 T362	V85-G89 WeakPolarHBondContact O-CA 3.29Å; V85-G89 PolarHBondContact O-N 3.4Å; G86-G89 PolarHBondContact O-N 3.36Å; G89-G91 VanDerWaalsContact C-N 3.32Å; G89-G91 PolarHBondContact O-N 2.8Å; G89-A92 WeakPolarHBondContact O-CB 3.25Å; G89-A92 PolarHBondContact O-N 2.65Å; G89-A93 WeakPolarHBondContact O-CB 3.43Å; G89-A93 PolarHBondContact O-N 3.31Å; G89-T362 WeakPolarHBondContact CA-O 3.34Å; G89-T362 WeakPolarHBondContact O-CB 3.38Å
90	T	94.4	Very high	92.9	Very high	0 Å²	0	2.7 Å²	2.7	0%	0	2%	0.018	C	C	.	.	H	α-helix	trans	-67	-36.2	174.9	-51.9	0	0	0	0	111.2	G86 A93 S94 T98 H454	G86-T90 VanDerWaalsContact O-CB 3.27Å; G86-T90 WeakPolarHBondContact O-CB 3.33Å; G86-T90 PolarHBondContact O-N 3.19Å; G86-T90 PolarHBondContact O-OG1 2.91Å; T90-A93 PolarHBondContact O-N 3.35Å; T90-S94 WeakPolarHBondContact O-CB 3.46Å; T90-S94 PolarHBondContact O-N 3.02Å; T90-S94 PolarHBondContact O-OG 2.95Å; T90-T98 HydrophobicContact CG2-CG2 4.44Å; T90-T98 WeakPolarHBondContact CG2-OG1 3.44Å; T90-H454 WeakPolarHBondContact CG2-NE2 3.24Å
91	G	96.2	Very high	93	Very high	0 Å²	0	3.3 Å²	3.3	0%	0	2%	0.02	C	C	.	.	H	α-helix	trans	-63.1	-45.2	171.4	0	0	0	0	0	112.4	L87 A88 G89 A93 G95 Y236 M333	L87-G91 WeakPolarHBondContact O-CA 3.45Å; L87-G91 PolarHBondContact O-N 3.45Å; A88-G91 PolarHBondContact O-N 2.69Å; G89-G91 VanDerWaalsContact C-N 3.32Å; G89-G91 PolarHBondContact O-N 2.8Å; G91-A93 VanDerWaalsContact C-N 3.31Å; G91-A93 PolarHBondContact O-N 2.89Å; G91-G95 WeakPolarHBondContact CA-O 3.43Å; G91-G95 VanDerWaalsContact O-CA 3.3Å; G91-G95 WeakPolarHBondContact O-CA 3.41Å; G91-G95 PolarHBondContact O-N 3.48Å; G91-Y236 PolarHBondContact O-OH 2.88Å; G91-M333 WeakPolarHBondContact O-CG 3.49Å
92	A	96.3	Very high	93.5	Very high	1 Å²	1	3.5 Å²	3.5	1%	0.008	2%	0.022	C	C	.	.	H	α-helix	trans	-58.8	-44.3	174.3	0	0	0	0	0	111.3	A88 G89 Y236 G332 R336 V343 A365	A88-A92 WeakPolarHBondContact O-CB 3.49Å; A88-A92 PolarHBondContact O-N 2.98Å; G89-A92 WeakPolarHBondContact O-CB 3.25Å; G89-A92 PolarHBondContact O-N 2.65Å; A92-Y236 PolarHBondContact O-OH 2.95Å; A92-G332 VanDerWaalsContact CB-O 3.25Å; A92-G332 WeakPolarHBondContact CB-O 3.28Å; A92-R336 HydrophobicContact CB-CB 4.27Å; A92-R336 WeakPolarHBondContact O-CD 3.42Å; A92-R336 PolarHBondContact O-NH1 3.01Å; A92-V343 HydrophobicContact CB-CG1 3.93Å; A92-A365 HydrophobicContact CB-CB 3.95Å
93	A	93.2	Very high	93.8	Very high	26 Å²	26	3.2 Å²	3.2	22%	0.215	2%	0.02	C	C	.	.	H	α-helix	trans	-69.2	-49.1	-178.7	0	0	0	0	0	113	G89 T90 G91 R336 T362	G89-A93 WeakPolarHBondContact O-CB 3.43Å; G89-A93 PolarHBondContact O-N 3.31Å; T90-A93 PolarHBondContact O-N 3.35Å; G91-A93 VanDerWaalsContact C-N 3.31Å; G91-A93 PolarHBondContact O-N 2.89Å; A93-R336 PolarHBondContact O-NH1 2.75Å; A93-R336 VanDerWaalsContact O-NH1 3.08Å; A93-T362 HydrophobicContact CB-CG2 3.97Å
94	S	92.3	Very high	93.9	Very high	4 Å²	4	2.8 Å²	2.8	3%	0.028	2%	0.018	C	C	.	.	H	α-helix	trans	-124.1	-13.8	-162.2	74	0	0	0	0	115	T90 R267 D273	T90-S94 WeakPolarHBondContact O-CB 3.46Å; T90-S94 PolarHBondContact O-N 3.02Å; T90-S94 PolarHBondContact O-OG 2.95Å; S94-R267 PolarHBondContact O-NH2 3.41Å; S94-D273 VanDerWaalsContact CB-OD2 3.31Å; S94-D273 WeakPolarHBondContact CB-OD2 3.08Å
95	G	95.3	Very high	94	Very high	0 Å²	0	2.9 Å²	2.9	0%	0	2%	0.019	C	C	.	.			trans	94.5	-155.3	-179	0	0	0	0	0	114.9	G91 A97 Y236 S262	G91-G95 WeakPolarHBondContact CA-O 3.43Å; G91-G95 VanDerWaalsContact O-CA 3.3Å; G91-G95 WeakPolarHBondContact O-CA 3.41Å; G91-G95 PolarHBondContact O-N 3.48Å; G95-A97 PolarHBondContact O-N 2.83Å; G95-Y236 PolarHBondContact N-OH 3.48Å; G95-S262 CarbonylContact C-O 3.48Å; G95-S262 WeakPolarHBondContact CA-O 3.34Å
96	V	96.7	Very high	94.2	Very high	0 Å²	0	2.9 Å²	2.9	0%	0	2%	0.019	C	C	.	.	G	3₁₀ helix	trans	-74.8	-19.7	-162.8	-53.3	0	0	0	0	114.9	T98 V99 S262 F263 I265 M325 M333	V96-T98 PolarHBondContact O-N 3.28Å; V96-T98 VanDerWaalsContact O-N 3.08Å; V96-V99 VanDerWaalsContact O-CB 3.32Å; V96-V99 WeakPolarHBondContact O-CB 3.49Å; V96-V99 WeakPolarHBondContact O-CG1 3.49Å; V96-V99 PolarHBondContact O-N 3.47Å; V96-S262 WeakPolarHBondContact CG2-O 3.09Å; V96-S262 PolarHBondContact N-O 2.92Å; V96-F263 HydrophobicContact CG1-CD1 4Å; V96-F263 HydrophobicContact CG1-CE1 4.46Å; V96-F263 VanDerWaalsContact CG2-C 3.44Å; V96-F263 WeakPolarHBondContact CG2-O 3.46Å; V96-I265 HydrophobicContact CG2-CG2 4.15Å; V96-M325 HydrophobicContact CB-CE 4.03Å; V96-M325 HydrophobicContact CG1-CE 4.14Å; V96-M333 HydrophobicContact CG1-CE 4.24Å; V96-M333 HydrophobicContact CG1-SD 3.75Å
97	A	95.2	Very high	94.4	Very high	0 Å²	0	5.2 Å²	5.2	0%	0	3%	0.033	C	C	.	.	G	3₁₀ helix	trans	-59.5	-26.6	-174.4	0	0	0	0	0	113.9	G95 V99 T100 R267 I274	G95-A97 PolarHBondContact O-N 2.83Å; A97-V99 PolarHBondContact O-N 3.36Å; A97-V99 VanDerWaalsContact O-N 3.08Å; A97-T100 WeakPolarHBondContact O-CB 3.47Å; A97-T100 VanDerWaalsContact O-CG2 3.32Å; A97-T100 WeakPolarHBondContact O-CG2 3.45Å; A97-T100 PolarHBondContact O-N 2.9Å; A97-T100 VanDerWaalsContact O-N 3.08Å; A97-T100 PolarHBondContact O-OG1 2.56Å; A97-R267 HydrophobicContact CB-CG 4.39Å; A97-R267 VanDerWaalsContact CB-NH2 3.28Å; A97-I274 HydrophobicContact CB-CB 4.5Å; A97-I274 HydrophobicContact CB-CD1 4.11Å
98	T	94.1	Very high	94.5	Very high	0 Å²	0	5.9 Å²	5.9	0%	0	4%	0.036	C	C	.	.	G	3₁₀ helix	trans	-59.3	-19.7	174.9	-169.3	0	0	0	0	113.4	T90 V96 T100 F101 V329	T90-T98 HydrophobicContact CG2-CG2 4.44Å; T90-T98 WeakPolarHBondContact CG2-OG1 3.44Å; V96-T98 PolarHBondContact O-N 3.28Å; V96-T98 VanDerWaalsContact O-N 3.08Å; T98-T100 PolarHBondContact O-N 3.28Å; T98-F101 WeakPolarHBondContact O-CD2 3.48Å; T98-F101 PolarHBondContact O-N 3.01Å; T98-F101 WeakPolarHBondContact OG1-CD2 3.47Å; T98-V329 HydrophobicContact CG2-CB 4.37Å; T98-V329 HydrophobicContact CG2-CG1 3.75Å; T98-V329 HydrophobicContact CG2-CG2 3.68Å
99	V	94.8	Very high	94.6	Very high	0 Å²	0	5.9 Å²	5.9	0%	0	4%	0.036	C	C	.	.	G	3₁₀ helix	trans	-63.9	-21	177.1	79.6	0	0	0	0	112.5	V96 A97 F101 E102 W103 I265 M325 V329	V96-V99 VanDerWaalsContact O-CB 3.32Å; V96-V99 WeakPolarHBondContact O-CB 3.49Å; V96-V99 WeakPolarHBondContact O-CG1 3.49Å; V96-V99 PolarHBondContact O-N 3.47Å; A97-V99 PolarHBondContact O-N 3.36Å; A97-V99 VanDerWaalsContact O-N 3.08Å; V99-F101 PolarHBondContact O-N 3.43Å; V99-E102 WeakPolarHBondContact O-CA 3.47Å; V99-E102 WeakPolarHBondContact O-CB 3.21Å; V99-E102 PolarHBondContact O-N 3.36Å; V99-W103 HydrophobicContact CG1-CD2 3.99Å; V99-W103 HydrophobicContact CG1-CE3 4.04Å; V99-W103 HydrophobicContact CG1-CH2 4.25Å; V99-W103 HydrophobicContact CG1-CZ2 4.22Å; V99-W103 HydrophobicContact CG1-CZ3 4.16Å; V99-W103 HydrophobicContact CG2-CD2 4.1Å; V99-W103 HydrophobicContact CG2-CG 4.24Å; V99-W103 HydrophobicContact CG2-CZ2 4.1Å; V99-W103 PolarHBondContact O-N 2.9Å; V99-I265 HydrophobicContact CG1-CG2 4.18Å; V99-M325 HydrophobicContact CB-CG 4.45Å; V99-M325 HydrophobicContact CG2-CB 3.6Å; V99-M325 HydrophobicContact CG2-CG 3.94Å; V99-V329 HydrophobicContact CB-CG2 4.42Å
100	T	93.7	Very high	94.7	Very high	0 Å²	0	6.4 Å²	6.4	0%	0	4%	0.04	C	C	.	.	H	α-helix	trans	-59.1	-30.7	178.4	55.9	0	0	0	0	112	A97 T98 E102 W103 T104 I265 I279 M283 Y655	A97-T100 WeakPolarHBondContact O-CB 3.47Å; A97-T100 VanDerWaalsContact O-CG2 3.32Å; A97-T100 WeakPolarHBondContact O-CG2 3.45Å; A97-T100 PolarHBondContact O-N 2.9Å; A97-T100 VanDerWaalsContact O-N 3.08Å; A97-T100 PolarHBondContact O-OG1 2.56Å; T98-T100 PolarHBondContact O-N 3.28Å; T100-E102 PolarHBondContact O-N 2.89Å; T100-W103 PolarHBondContact O-N 3.28Å; T100-T104 PolarHBondContact O-N 2.85Å; T100-T104 VanDerWaalsContact O-N 3.12Å; T100-T104 PolarHBondContact O-OG1 3.42Å; T100-T104 VanDerWaalsContact O-OG1 3.07Å; T100-I265 HydrophobicContact CG2-CB 3.9Å; T100-I265 HydrophobicContact CG2-CD1 4.49Å; T100-I265 HydrophobicContact CG2-CG2 4.3Å; T100-I279 HydrophobicContact CG2-CD1 3.96Å; T100-I279 HydrophobicContact CG2-CG1 4.35Å; T100-I279 HydrophobicContact CG2-CG2 3.94Å; T100-M283 WeakPolarHBondContact O-CE 3.42Å; T100-Y655 HydrophobicContact CG2-CE1 4.41Å
101	F	90.3	Very high	94.9	Very high	13 Å²	13	8.7 Å²	8.7	6%	0.057	5%	0.052	C	C	.	.	H	α-helix	trans	-53.8	-34.6	170.9	-61.5	-57.5	0	0	0	112.3	T98 V99 I274 M283 I453 E457 Y526	T98-F101 WeakPolarHBondContact O-CD2 3.48Å; T98-F101 PolarHBondContact O-N 3.01Å; T98-F101 WeakPolarHBondContact OG1-CD2 3.47Å; V99-F101 PolarHBondContact O-N 3.43Å; F101-I274 HydrophobicContact CE2-CD1 3.78Å; F101-I274 HydrophobicContact CZ-CD1 4.09Å; F101-I274 HydrophobicContact CZ-CG1 4.47Å; F101-I274 HydrophobicContact CZ-CG2 4.44Å; F101-M283 HydrophobicContact CB-CE 4.02Å; F101-M283 HydrophobicContact CD1-CE 2.92Å; F101-M283 HydrophobicContact CE1-CE 3.35Å; F101-M283 HydrophobicContact CG-CE 3.62Å; F101-M283 HydrophobicContact CZ-CE 4.35Å; F101-I453 HydrophobicContact CD2-CG2 3.43Å; F101-I453 VanDerWaalsContact CD2-CG2 3.43Å; F101-I453 HydrophobicContact CE2-CG2 3.66Å; F101-I453 HydrophobicContact CG-CG2 4.05Å; F101-I453 HydrophobicContact CZ-CG2 4.45Å; F101-E457 HydrophobicContact CD1-CB 4.4Å; F101-E457 HydrophobicContact CD1-CG 3.51Å; F101-E457 HydrophobicContact CE1-CB 4Å; F101-E457 HydrophobicContact CE1-CG 3.58Å; F101-E457 HydrophobicContact CG-CG 4.15Å; F101-E457 HydrophobicContact CZ-CB 4.5Å; F101-E457 HydrophobicContact CZ-CG 4.2Å; F101-Y526 WeakPolarHBondContact CZ-OH 3.28Å
102	E	93.7	Very high	94.9	Very high	5 Å²	5	8.7 Å²	8.7	2%	0.023	5%	0.052	C	C	.	.	H	α-helix	trans	-89.9	-45.7	178.9	-60.3	-54.7	134.3	0	0	112.5	I79 H83 L87 V99 T100 T104 S105 K321 P324	I79-E102 WeakPolarHBondContact CD1-OE2 3.42Å; H83-E102 IonicContact CD2-OE1 3.9Å; H83-E102 PolarHBondContact CD2-OE1 3.28Å; H83-E102 IonicContact NE2-OE1 2.9Å; H83-E102 PolarHBondContact NE2-OE1 2.86Å; L87-E102 HydrophobicContact CD1-CG 3.62Å; L87-E102 HydrophobicContact CD2-CG 4.4Å; V99-E102 WeakPolarHBondContact O-CA 3.47Å; V99-E102 WeakPolarHBondContact O-CB 3.21Å; V99-E102 PolarHBondContact O-N 3.36Å; T100-E102 PolarHBondContact O-N 2.89Å; E102-T104 VanDerWaalsContact C-N 3.34Å; E102-T104 PolarHBondContact O-N 3.06Å; E102-S105 WeakPolarHBondContact O-CB 3.49Å; E102-S105 PolarHBondContact O-N 3.43Å; E102-S105 PolarHBondContact O-OG 3.1Å; E102-K321 WeakPolarHBondContact OE2-CD 3.16Å; E102-K321 WeakPolarHBondContact OE2-CE 3.44Å; E102-K321 IonicContact OE2-NZ 2.63Å; E102-K321 PolarHBondContact OE2-NZ 2.65Å; E102-P324 HydrophobicContact CB-CB 4.32Å; E102-P324 HydrophobicContact CB-CG 4.21Å; E102-P324 HydrophobicContact CG-CB 3.84Å; E102-P324 HydrophobicContact CG-CG 3.97Å
103	W	94.8	Very high	94.9	Very high	2 Å²	2	8.7 Å²	8.7	1%	0.008	5%	0.051	C	C	.	.	H	α-helix	trans	-70.3	-27	-171.8	-71.1	-1.9	0	0	0	113.9	V99 T100 S105 S106 I265 L322 M325 I654 Y655 Y658	V99-W103 HydrophobicContact CG1-CD2 3.99Å; V99-W103 HydrophobicContact CG1-CE3 4.04Å; V99-W103 HydrophobicContact CG1-CH2 4.25Å; V99-W103 HydrophobicContact CG1-CZ2 4.22Å; V99-W103 HydrophobicContact CG1-CZ3 4.16Å; V99-W103 HydrophobicContact CG2-CD2 4.1Å; V99-W103 HydrophobicContact CG2-CG 4.24Å; V99-W103 HydrophobicContact CG2-CZ2 4.1Å; V99-W103 PolarHBondContact O-N 2.9Å; T100-W103 PolarHBondContact O-N 3.28Å; W103-S105 PolarHBondContact O-N 2.92Å; W103-S106 WeakPolarHBondContact O-CB 3.49Å; W103-S106 PolarHBondContact O-N 3.43Å; W103-S106 VanDerWaalsContact O-N 3.1Å; W103-I265 HydrophobicContact CZ3-CD1 4.39Å; W103-L322 PolarHBondContact NE1-O 2.87Å; W103-M325 HydrophobicContact CH2-CE 4.3Å; W103-M325 HydrophobicContact CH2-SD 3.6Å; W103-M325 VanDerWaalsContact CH2-SD 3.6Å; W103-M325 HydrophobicContact CZ2-CB 4.11Å; W103-M325 HydrophobicContact CZ2-CG 4.2Å; W103-M325 HydrophobicContact CZ2-SD 3.38Å; W103-M325 WeakPolarHBondContact CZ2-SD 3.32Å; W103-I654 HydrophobicContact CD2-CD1 3.64Å; W103-I654 HydrophobicContact CD2-CG1 4.25Å; W103-I654 HydrophobicContact CE3-CD1 3.78Å; W103-I654 HydrophobicContact CE3-CG1 3.85Å; W103-I654 HydrophobicContact CG-CD1 4.23Å; W103-I654 HydrophobicContact CH2-CB 3.8Å; W103-I654 HydrophobicContact CH2-CD1 3.97Å; W103-I654 HydrophobicContact CH2-CG1 3.97Å; W103-I654 HydrophobicContact CZ2-CB 4.35Å; W103-I654 HydrophobicContact CZ2-CD1 3.82Å; W103-I654 HydrophobicContact CZ2-CG1 4.33Å; W103-I654 HydrophobicContact CZ3-CB 3.89Å; W103-I654 HydrophobicContact CZ3-CD1 3.95Å; W103-I654 HydrophobicContact CZ3-CG1 3.71Å; W103-Y655 HydrophobicContact CB-CE2 3.6Å; W103-Y655 AromaticContact CE3-CD2 3.97Å; W103-Y655 HydrophobicContact CE3-CD2 3.97Å; W103-Y655 AromaticContact CE3-CE2 3.95Å; W103-Y655 HydrophobicContact CE3-CE2 3.95Å; W103-Y655 HydrophobicContact CG-CE2 4.46Å; W103-Y658 AromaticContact CH2-CD2 3.56Å; W103-Y658 HydrophobicContact CH2-CD2 3.56Å; W103-Y658 AromaticContact CH2-CE2 3.89Å; W103-Y658 HydrophobicContact CH2-CE2 3.89Å; W103-Y658 HydrophobicContact CH2-CG 4.49Å; W103-Y658 HydrophobicContact CZ3-CD2 4.06Å
104	T	94.5	Very high	95.1	Very high	6 Å²	6	10.3 Å²	10.3	4%	0.037	5%	0.052	C	C	.	.	H	α-helix	trans	-60.7	-31.1	171.1	-55.9	0	0	0	0	111.7	T100 E102 S106 V107 M108 M283 P284 A287 Y655	T100-T104 PolarHBondContact O-N 2.85Å; T100-T104 VanDerWaalsContact O-N 3.12Å; T100-T104 PolarHBondContact O-OG1 3.42Å; T100-T104 VanDerWaalsContact O-OG1 3.07Å; E102-T104 VanDerWaalsContact C-N 3.34Å; E102-T104 PolarHBondContact O-N 3.06Å; T104-S106 PolarHBondContact O-N 3.46Å; T104-V107 PolarHBondContact O-N 3.41Å; T104-V107 VanDerWaalsContact O-N 3.11Å; T104-M108 PolarHBondContact O-N 3.44Å; T104-M108 VanDerWaalsContact O-N 3.15Å; T104-M283 HydrophobicContact CG2-CG 4.03Å; T104-M283 WeakPolarHBondContact OG1-CG 3.43Å; T104-M283 PolarHBondContact OG1-SD 2.99Å; T104-P284 HydrophobicContact CG2-CB 4.41Å; T104-P284 HydrophobicContact CG2-CG 4.08Å; T104-A287 HydrophobicContact CG2-CB 3.75Å; T104-Y655 PolarHBondContact N-OH 3.21Å; T104-Y655 PolarHBondContact OG1-OH 3.19Å
105	S	94	Very high	95.2	Very high	3 Å²	3	12 Å²	12	2%	0.021	6%	0.061	C	C	.	.	H	α-helix	trans	-61	-33.8	175.5	-52.9	0	0	0	0	112.3	E102 W103 V107 M108 L109 W291	E102-S105 WeakPolarHBondContact O-CB 3.49Å; E102-S105 PolarHBondContact O-N 3.43Å; E102-S105 PolarHBondContact O-OG 3.1Å; W103-S105 PolarHBondContact O-N 2.92Å; S105-V107 PolarHBondContact O-N 3.33Å; S105-M108 PolarHBondContact O-N 3Å; S105-M108 VanDerWaalsContact O-N 3.17Å; S105-L109 WeakPolarHBondContact O-CB 3.19Å; S105-L109 WeakPolarHBondContact O-CG 3.39Å; S105-L109 PolarHBondContact O-N 3.35Å; S105-W291 VanDerWaalsContact CB-CE2 3.49Å; S105-W291 PolarHBondContact OG-NE1 2.9Å
106	S	94.6	Very high	95.3	Very high	0 Å²	0	12.2 Å²	12.2	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-64.5	-21.4	178.3	-58.8	0	0	0	0	113.1	W103 T104 P110 A318 L322	W103-S106 WeakPolarHBondContact O-CB 3.49Å; W103-S106 PolarHBondContact O-N 3.43Å; W103-S106 VanDerWaalsContact O-N 3.1Å; T104-S106 PolarHBondContact O-N 3.46Å; S106-P110 WeakPolarHBondContact O-CD 3.02Å; S106-P110 WeakPolarHBondContact O-CG 3.44Å; S106-A318 PolarHBondContact OG-O 2.92Å; S106-L322 WeakPolarHBondContact OG-CD2 3.5Å
107	V	95	Very high	95.2	Very high	49 Å²	49	12.2 Å²	12.2	30%	0.297	6%	0.061	S	C	.	.	H	α-helix	trans	-89.5	-39.6	171.8	-175.7	0	0	0	0	111.4	T104 S105 P110 I111 L648 V651	T104-V107 PolarHBondContact O-N 3.41Å; T104-V107 VanDerWaalsContact O-N 3.11Å; S105-V107 PolarHBondContact O-N 3.33Å; V107-P110 WeakPolarHBondContact O-CD 3.28Å; V107-I111 HydrophobicContact CG1-CD1 4.28Å; V107-I111 PolarHBondContact O-N 2.84Å; V107-L648 HydrophobicContact CG1-CD2 4.39Å; V107-L648 HydrophobicContact CG2-CD2 4.36Å; V107-V651 HydrophobicContact CG2-CG1 3.91Å
108	M	96.4	Very high	95.2	Very high	14 Å²	14	13.1 Å²	13.1	7%	0.069	7%	0.067	C	C	.	.	H	α-helix	trans	-70.5	-29.9	-178.9	-69.1	-56.4	120.7	0	0	113.8	T104 S105 I111 L112 P284 A287 L288 W291	T104-M108 PolarHBondContact O-N 3.44Å; T104-M108 VanDerWaalsContact O-N 3.15Å; S105-M108 PolarHBondContact O-N 3Å; S105-M108 VanDerWaalsContact O-N 3.17Å; M108-I111 HydrophobicContact CE-CD1 3.63Å; M108-I111 CarbonylContact O-C 3.54Å; M108-I111 WeakPolarHBondContact O-CB 3.23Å; M108-I111 PolarHBondContact O-N 3Å; M108-I111 HydrophobicContact SD-CD1 3.9Å; M108-L112 PolarHBondContact O-N 3.34Å; M108-P284 HydrophobicContact CE-CB 3.91Å; M108-A287 HydrophobicContact CB-CB 4.47Å; M108-A287 HydrophobicContact CG-CB 3.59Å; M108-L288 HydrophobicContact SD-CB 4.2Å; M108-L288 HydrophobicContact SD-CD1 3.97Å; M108-W291 HydrophobicContact CB-CB 4.11Å; M108-W291 HydrophobicContact CB-CG 4.19Å
109	L	97.3	Very high	95.2	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-64.9	-45.9	178.4	-83.1	162.7	0	0	0	113.3	S105 I111 L112 G113 W291 C314 C317 A318 K321	S105-L109 WeakPolarHBondContact O-CB 3.19Å; S105-L109 WeakPolarHBondContact O-CG 3.39Å; S105-L109 PolarHBondContact O-N 3.35Å; L109-I111 VanDerWaalsContact C-N 3.3Å; L109-I111 PolarHBondContact O-N 2.91Å; L109-L112 HydrophobicContact CD2-CD2 4.23Å; L109-L112 WeakPolarHBondContact O-CB 3.3Å; L109-L112 PolarHBondContact O-N 3.31Å; L109-G113 PolarHBondContact O-N 3.41Å; L109-W291 HydrophobicContact CD1-CE3 4.4Å; L109-W291 HydrophobicContact CD1-CH2 4.33Å; L109-W291 HydrophobicContact CD1-CZ3 4.21Å; L109-W291 HydrophobicContact CD2-CD2 4.23Å; L109-W291 HydrophobicContact CD2-CE3 3.45Å; L109-W291 VanDerWaalsContact CD2-CE3 3.45Å; L109-W291 HydrophobicContact CD2-CZ3 3.65Å; L109-W291 HydrophobicContact CG-CD2 4.17Å; L109-W291 HydrophobicContact CG-CE3 3.86Å; L109-W291 HydrophobicContact CG-CZ3 4.13Å; L109-C314 HydrophobicContact CB-CB 4.4Å; L109-C314 HydrophobicContact CD2-CB 4.46Å; L109-C314 WeakPolarHBondContact O-CB 3.18Å; L109-C317 HydrophobicContact CD1-CB 3.89Å; L109-C317 VanDerWaalsContact CD1-SG 3.57Å; L109-C317 HydrophobicContact CD2-CB 4.3Å; L109-A318 HydrophobicContact CB-CB 4Å; L109-A318 HydrophobicContact CD1-CB 3.84Å; L109-K321 HydrophobicContact CD1-CG 4.29Å
110	P	96.9	Very high	95.1	Very high	12 Å²	12	13.1 Å²	13.1	8%	0.078	7%	0.067	C	C	.	.	H	α-helix	trans	-57	-40.2	166.8	-28.5	34.8	0	0	0	113.3	S106 V107 L112 G113 W114 L647	S106-P110 WeakPolarHBondContact O-CD 3.02Å; S106-P110 WeakPolarHBondContact O-CG 3.44Å; V107-P110 WeakPolarHBondContact O-CD 3.28Å; P110-L112 PolarHBondContact O-N 2.91Å; P110-G113 PolarHBondContact O-N 2.95Å; P110-W114 HydrophobicContact CB-CE3 4.48Å; P110-W114 WeakPolarHBondContact O-CB 3.27Å; P110-W114 PolarHBondContact O-N 3.45Å; P110-L647 HydrophobicContact CG-CD2 3.79Å
111	I	97.4	Very high	95	Very high	48 Å²	48	13.3 Å²	13.3	25%	0.246	7%	0.068	C	C	.	.	H	α-helix	trans	-61.4	-46	176.1	-71.9	168.6	0	0	0	110.7	V107 M108 L109 G113 W114 I115 F116 L288	V107-I111 HydrophobicContact CG1-CD1 4.28Å; V107-I111 PolarHBondContact O-N 2.84Å; M108-I111 HydrophobicContact CE-CD1 3.63Å; M108-I111 CarbonylContact O-C 3.54Å; M108-I111 WeakPolarHBondContact O-CB 3.23Å; M108-I111 PolarHBondContact O-N 3Å; M108-I111 HydrophobicContact SD-CD1 3.9Å; L109-I111 VanDerWaalsContact C-N 3.3Å; L109-I111 PolarHBondContact O-N 2.91Å; I111-G113 PolarHBondContact O-N 3.48Å; I111-W114 PolarHBondContact O-N 2.89Å; I111-I115 HydrophobicContact CG2-CD1 4.29Å; I111-I115 WeakPolarHBondContact O-CA 3.14Å; I111-I115 VanDerWaalsContact O-CB 3.24Å; I111-I115 WeakPolarHBondContact O-CB 3.46Å; I111-I115 PolarHBondContact O-N 2.95Å; I111-F116 HydrophobicContact CG2-CD2 3.84Å; I111-F116 HydrophobicContact CG2-CE2 3.62Å; I111-L288 HydrophobicContact CG2-CD1 4.27Å
112	L	97.4	Very high	94.9	Very high	0 Å²	0	14.1 Å²	14.1	0%	0	7%	0.072	C	C	.	.	I	π-helix	trans	-53.7	-54	174	169.4	65.2	0	0	0	110.8	M108 L109 P110 W114 F116 V117 W291 I297 V298	M108-L112 PolarHBondContact O-N 3.34Å; L109-L112 HydrophobicContact CD2-CD2 4.23Å; L109-L112 WeakPolarHBondContact O-CB 3.3Å; L109-L112 PolarHBondContact O-N 3.31Å; P110-L112 PolarHBondContact O-N 2.91Å; L112-W114 PolarHBondContact O-N 3.32Å; L112-F116 HydrophobicContact CD1-CB 4.24Å; L112-F116 PolarHBondContact O-N 3.42Å; L112-V117 HydrophobicContact CD1-CG2 3.46Å; L112-V117 VanDerWaalsContact CD1-CG2 3.46Å; L112-V117 HydrophobicContact CG-CG2 3.78Å; L112-V117 WeakPolarHBondContact O-CG2 3.22Å; L112-V117 PolarHBondContact O-N 2.88Å; L112-W291 WeakPolarHBondContact CD1-O 3.41Å; L112-W291 WeakPolarHBondContact CD2-O 3.42Å; L112-I297 HydrophobicContact CD2-CG2 4.04Å; L112-V298 HydrophobicContact CD1-CG2 4.17Å
113	G	96.4	Very high	94.6	Very high	0 Å²	0	14 Å²	14	0%	0	7%	0.071	C	C	.	.	I	π-helix	trans	-67.1	-34.7	-175.6	0	0	0	0	0	114.8	L109 P110 I111 P118 M307	L109-G113 PolarHBondContact O-N 3.41Å; P110-G113 PolarHBondContact O-N 2.95Å; I111-G113 PolarHBondContact O-N 3.48Å; G113-P118 WeakPolarHBondContact O-CD 2.91Å; G113-M307 WeakPolarHBondContact O-CE 3.49Å
114	W	96.1	Very high	94.1	Very high	60 Å²	60	15.5 Å²	15.5	23%	0.227	9%	0.088	C	C	.	.	I	π-helix	trans	-96.5	-24.3	-175.5	-86.1	-110.5	0	0	0	114.2	P110 I111 L112 K311 I315 V640 N641 A644	P110-W114 HydrophobicContact CB-CE3 4.48Å; P110-W114 WeakPolarHBondContact O-CB 3.27Å; P110-W114 PolarHBondContact O-N 3.45Å; I111-W114 PolarHBondContact O-N 2.89Å; L112-W114 PolarHBondContact O-N 3.32Å; W114-K311 HydrophobicContact CD2-CD 4.04Å; W114-K311 HydrophobicContact CD2-CG 4.1Å; W114-K311 HydrophobicContact CE3-CB 4.36Å; W114-K311 HydrophobicContact CE3-CD 4.3Å; W114-K311 HydrophobicContact CE3-CG 3.86Å; W114-K311 HydrophobicContact CH2-CB 3.59Å; W114-K311 HydrophobicContact CH2-CD 4.04Å; W114-K311 HydrophobicContact CH2-CG 3.85Å; W114-K311 HydrophobicContact CZ2-CB 4.16Å; W114-K311 HydrophobicContact CZ2-CD 3.77Å; W114-K311 HydrophobicContact CZ2-CG 4.11Å; W114-K311 HydrophobicContact CZ3-CB 3.73Å; W114-K311 HydrophobicContact CZ3-CD 4.31Å; W114-K311 HydrophobicContact CZ3-CG 3.75Å; W114-I315 HydrophobicContact CH2-CD1 3.59Å; W114-I315 HydrophobicContact CH2-CG1 4.03Å; W114-I315 HydrophobicContact CZ3-CD1 4.31Å; W114-I315 HydrophobicContact CZ3-CG1 4.26Å; W114-V640 HydrophobicContact CH2-CB 4.21Å; W114-V640 HydrophobicContact CH2-CG2 4.39Å; W114-V640 HydrophobicContact CZ2-CB 4.2Å; W114-V640 HydrophobicContact CZ2-CG2 3.97Å; W114-N641 WeakPolarHBondContact CZ2-OD1 3.17Å; W114-N641 PolarHBondContact NE1-OD1 3.01Å; W114-A644 HydrophobicContact CH2-CB 3.94Å; W114-A644 HydrophobicContact CZ2-CB 4.02Å
115	I	95.8	Very high	93.6	Very high	41 Å²	41	15.6 Å²	15.6	21%	0.21	9%	0.088	C	C	.	.	I	π-helix	trans	-112	-58.5	-172.1	-58.9	-175.2	0	0	0	111.1	I111 I475 F476 W561	I111-I115 HydrophobicContact CG2-CD1 4.29Å; I111-I115 WeakPolarHBondContact O-CA 3.14Å; I111-I115 VanDerWaalsContact O-CB 3.24Å; I111-I115 WeakPolarHBondContact O-CB 3.46Å; I111-I115 PolarHBondContact O-N 2.95Å; I115-I475 HydrophobicContact CG2-CG2 4.44Å; I115-F476 HydrophobicContact CD1-CZ 4.26Å; I115-F476 HydrophobicContact CG2-CE1 4.19Å; I115-F476 HydrophobicContact CG2-CE2 4.03Å; I115-F476 HydrophobicContact CG2-CZ 3.39Å; I115-W561 HydrophobicContact CB-CZ3 4.25Å; I115-W561 HydrophobicContact CG1-CH2 4.3Å; I115-W561 HydrophobicContact CG1-CZ3 4.33Å; I115-W561 HydrophobicContact CG2-CE3 4.2Å; I115-W561 HydrophobicContact CG2-CZ3 4.05Å
116	F	96.4	Very high	92.9	Very high	3 Å²	3	17.1 Å²	17.1	1%	0.013	10%	0.098	C	C	.	.	I	π-helix	trans	-81	-54.3	-167.6	-74.7	-103.6	0	0	0	112.3	I111 L112 I119 Y120 L288 C292 I475	I111-F116 HydrophobicContact CG2-CD2 3.84Å; I111-F116 HydrophobicContact CG2-CE2 3.62Å; L112-F116 HydrophobicContact CD1-CB 4.24Å; L112-F116 PolarHBondContact O-N 3.42Å; F116-I119 PolarHBondContact O-N 2.9Å; F116-Y120 HydrophobicContact CB-CD2 4.34Å; F116-Y120 HydrophobicContact CB-CE2 3.77Å; F116-Y120 HydrophobicContact CD1-CE2 4.24Å; F116-Y120 AromaticContact CD1-CZ 4Å; F116-Y120 WeakPolarHBondContact CD1-OH 3.41Å; F116-Y120 WeakPolarHBondContact O-CD2 3.37Å; F116-Y120 PolarHBondContact O-N 3.03Å; F116-Y120 VanDerWaalsContact O-N 3.08Å; F116-L288 HydrophobicContact CE2-CD1 3.86Å; F116-L288 HydrophobicContact CZ-CD1 3.75Å; F116-L288 HydrophobicContact CZ-CG 4.35Å; F116-C292 HydrophobicContact CB-CB 4.38Å; F116-C292 HydrophobicContact CD1-CB 3.61Å; F116-C292 HydrophobicContact CD2-CB 3.89Å; F116-C292 HydrophobicContact CE1-CB 3.73Å; F116-C292 HydrophobicContact CE2-CB 4.04Å; F116-C292 HydrophobicContact CG-CB 3.7Å; F116-C292 HydrophobicContact CZ-CB 3.97Å; F116-I475 HydrophobicContact CB-CD1 4.48Å; F116-I475 HydrophobicContact CD1-CD1 3.19Å; F116-I475 HydrophobicContact CE1-CD1 3.38Å; F116-I475 HydrophobicContact CG-CD1 3.87Å; F116-I475 HydrophobicContact CZ-CD1 4.16Å
117	V	95.1	Very high	92.5	Very high	0 Å²	0	17.1 Å²	17.1	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-56.6	-43.8	-177.6	175.3	0	0	0	0	113.2	L112 I119 Y120 I121 C301 M307 V310	L112-V117 HydrophobicContact CD1-CG2 3.46Å; L112-V117 VanDerWaalsContact CD1-CG2 3.46Å; L112-V117 HydrophobicContact CG-CG2 3.78Å; L112-V117 WeakPolarHBondContact O-CG2 3.22Å; L112-V117 PolarHBondContact O-N 2.88Å; V117-I119 PolarHBondContact O-N 3.26Å; V117-Y120 PolarHBondContact O-N 3.38Å; V117-Y120 VanDerWaalsContact O-N 3.12Å; V117-I121 HydrophobicContact CG1-CD1 3.52Å; V117-I121 HydrophobicContact CG1-CG1 3.85Å; V117-I121 WeakPolarHBondContact O-CG1 3.05Å; V117-I121 PolarHBondContact O-N 3.41Å; V117-C301 HydrophobicContact CG1-CB 4.37Å; V117-C301 HydrophobicContact CG2-CB 3.64Å; V117-M307 HydrophobicContact CB-CE 4.35Å; V117-M307 HydrophobicContact CG1-CE 4.14Å; V117-V310 HydrophobicContact CB-CG1 4.43Å; V117-V310 HydrophobicContact CG1-CG1 3.83Å; V117-V310 HydrophobicContact CG2-CG1 4.32Å
118	P	94.1	Very high	92.3	Very high	19 Å²	19	15 Å²	15	12%	0.123	8%	0.084	C	C	.	.	H	α-helix	trans	-56.8	-35.8	177.9	-25.4	33.8	0	0	0	113.3	G113 K122 M307	G113-P118 WeakPolarHBondContact O-CD 2.91Å; P118-K122 WeakPolarHBondContact O-CB 3.18Å; P118-K122 VanDerWaalsContact O-CG 3.23Å; P118-K122 WeakPolarHBondContact O-CG 3.38Å; P118-K122 PolarHBondContact O-N 2.82Å; P118-M307 HydrophobicContact CB-SD 4.26Å; P118-M307 HydrophobicContact CG-CE 3.65Å; P118-M307 HydrophobicContact CG-SD 3.89Å
119	I	94.6	Very high	92	Very high	1 Å²	1	14.4 Å²	14.4	1%	0.005	8%	0.082	C	C	.	.	H	α-helix	trans	-72.3	-45.1	177	-67.7	175.3	0	0	0	110.1	F116 V117 I121 K122 S123 Y131 I475 L559 W561	F116-I119 PolarHBondContact O-N 2.9Å; V117-I119 PolarHBondContact O-N 3.26Å; I119-I121 PolarHBondContact O-N 2.69Å; I119-K122 PolarHBondContact O-N 3.43Å; I119-S123 WeakPolarHBondContact O-CB 3.41Å; I119-S123 PolarHBondContact O-N 3.2Å; I119-S123 PolarHBondContact O-OG 3.08Å; I119-Y131 HydrophobicContact CG2-CE2 3.72Å; I119-I475 HydrophobicContact CD1-CB 4.2Å; I119-I475 HydrophobicContact CD1-CD1 4.43Å; I119-I475 HydrophobicContact CD1-CG1 4.01Å; I119-I475 HydrophobicContact CD1-CG2 3.41Å; I119-I475 VanDerWaalsContact CD1-CG2 3.41Å; I119-L559 WeakPolarHBondContact CG2-O 3.26Å; I119-W561 HydrophobicContact CD1-CB 4.47Å; I119-W561 HydrophobicContact CD1-CE3 4.01Å
120	Y	93.8	Very high	91.5	Very high	0 Å²	0	16.1 Å²	16.1	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-61	-44.2	178.7	-58.8	-34.5	0	0	0	112.1	F116 V117 K122 S123 G124 M128 Y131 C292 V298 Y471	F116-Y120 HydrophobicContact CB-CD2 4.34Å; F116-Y120 HydrophobicContact CB-CE2 3.77Å; F116-Y120 HydrophobicContact CD1-CE2 4.24Å; F116-Y120 AromaticContact CD1-CZ 4Å; F116-Y120 WeakPolarHBondContact CD1-OH 3.41Å; F116-Y120 WeakPolarHBondContact O-CD2 3.37Å; F116-Y120 PolarHBondContact O-N 3.03Å; F116-Y120 VanDerWaalsContact O-N 3.08Å; V117-Y120 PolarHBondContact O-N 3.38Å; V117-Y120 VanDerWaalsContact O-N 3.12Å; Y120-K122 PolarHBondContact O-N 3.49Å; Y120-S123 WeakPolarHBondContact CA-OG 3.47Å; Y120-S123 PolarHBondContact O-N 2.98Å; Y120-S123 PolarHBondContact O-OG 3.37Å; Y120-G124 PolarHBondContact O-N 3.2Å; Y120-M128 HydrophobicContact CD1-SD 4.47Å; Y120-M128 HydrophobicContact CD2-CE 4.25Å; Y120-M128 HydrophobicContact CD2-SD 4.09Å; Y120-M128 HydrophobicContact CE1-SD 4.16Å; Y120-M128 HydrophobicContact CE2-CE 4.49Å; Y120-M128 HydrophobicContact CE2-SD 3.74Å; Y120-M128 HydrophobicContact CG-CE 4.29Å; Y120-M128 HydrophobicContact CG-SD 4.43Å; Y120-Y131 HydrophobicContact CD1-CD1 4.27Å; Y120-Y131 AromaticContact CD1-CD2 3.89Å; Y120-Y131 HydrophobicContact CD1-CD2 3.89Å; Y120-Y131 HydrophobicContact CD1-CE2 4.23Å; Y120-Y131 AromaticContact CD1-CG 3.93Å; Y120-Y131 HydrophobicContact CD1-CG 3.93Å; Y120-Y131 AromaticContact CE1-CD1 3.7Å; Y120-Y131 HydrophobicContact CE1-CD1 3.7Å; Y120-Y131 HydrophobicContact CE1-CD2 4.13Å; Y120-Y131 AromaticContact CE1-CE1 3.87Å; Y120-Y131 HydrophobicContact CE1-CE1 3.87Å; Y120-Y131 HydrophobicContact CE1-CE2 4.31Å; Y120-Y131 AromaticContact CE1-CG 3.83Å; Y120-Y131 HydrophobicContact CE1-CG 3.83Å; Y120-C292 WeakPolarHBondContact CE2-O 3.37Å; Y120-C292 PolarHBondContact OH-O 2.94Å; Y120-C292 VanDerWaalsContact OH-O 3.04Å; Y120-V298 HydrophobicContact CD2-CG1 3.51Å; Y120-V298 HydrophobicContact CE2-CG1 3.82Å; Y120-V298 HydrophobicContact CE2-CG2 4.25Å; Y120-V298 HydrophobicContact CG-CG1 4.44Å; Y120-Y471 HydrophobicContact CE1-CD1 4.46Å; Y120-Y471 HydrophobicContact CE1-CE1 4.44Å; Y120-Y471 WeakPolarHBondContact OH-CD1 3.46Å
121	I	90.3	Very high	91.3	Very high	4 Å²	4	15.5 Å²	15.5	2%	0.021	9%	0.086	C	C	.	.	H	α-helix	trans	-60.1	-48.4	175.6	-68.9	-178.4	0	0	0	111	V117 I119 S123 G124 L302 M307 L627 T630	V117-I121 HydrophobicContact CG1-CD1 3.52Å; V117-I121 HydrophobicContact CG1-CG1 3.85Å; V117-I121 WeakPolarHBondContact O-CG1 3.05Å; V117-I121 PolarHBondContact O-N 3.41Å; I119-I121 PolarHBondContact O-N 2.69Å; I121-S123 PolarHBondContact O-N 3.27Å; I121-G124 PolarHBondContact O-N 3.47Å; I121-G124 VanDerWaalsContact O-N 3.1Å; I121-L302 HydrophobicContact CG1-CD2 3.78Å; I121-M307 HydrophobicContact CD1-SD 4.23Å; I121-L627 WeakPolarHBondContact CG2-O 3.21Å; I121-T630 HydrophobicContact CB-CG2 4.08Å; I121-T630 HydrophobicContact CG2-CG2 3.68Å
122	K	89.3	Confident	91	Very high	29 Å²	29	13.2 Å²	13.2	13%	0.126	7%	0.074	C	C	.	.	H	α-helix	trans	-64.9	-27.5	178.1	-74.5	179.3	176.6	-173.4	0	113.5	P118 I119 Y120 G124 R558 R564 N565 T630	P118-K122 WeakPolarHBondContact O-CB 3.18Å; P118-K122 VanDerWaalsContact O-CG 3.23Å; P118-K122 WeakPolarHBondContact O-CG 3.38Å; P118-K122 PolarHBondContact O-N 2.82Å; I119-K122 PolarHBondContact O-N 3.43Å; Y120-K122 PolarHBondContact O-N 3.49Å; K122-G124 VanDerWaalsContact C-N 3.25Å; K122-G124 PolarHBondContact O-N 3.1Å; K122-R558 HydrophobicContact CB-CB 4.19Å; K122-R564 VanDerWaalsContact CD-O 3.31Å; K122-R564 WeakPolarHBondContact CD-O 3.19Å; K122-R564 PolarHBondContact NZ-O 3.27Å; K122-N565 PolarHBondContact NZ-OD1 3.26Å; K122-T630 HydrophobicContact CD-CG2 4.3Å; K122-T630 WeakPolarHBondContact CE-OG1 3.33Å; K122-T630 HydrophobicContact CG-CG2 3.65Å
123	S	87.2	Confident	90.7	Very high	2 Å²	2	14.6 Å²	14.6	1%	0.014	8%	0.08	C	C	.	.	H	α-helix	trans	-74.3	-17.4	176.5	74.1	0	0	0	0	113.3	I119 Y120 I121 V125 K134 L559	I119-S123 WeakPolarHBondContact O-CB 3.41Å; I119-S123 PolarHBondContact O-N 3.2Å; I119-S123 PolarHBondContact O-OG 3.08Å; Y120-S123 WeakPolarHBondContact CA-OG 3.47Å; Y120-S123 PolarHBondContact O-N 2.98Å; Y120-S123 PolarHBondContact O-OG 3.37Å; I121-S123 PolarHBondContact O-N 3.27Å; S123-V125 VanDerWaalsContact C-N 3.35Å; S123-V125 VanDerWaalsContact OG-CG1 3.22Å; S123-V125 WeakPolarHBondContact OG-CG1 3.35Å; S123-V125 VanDerWaalsContact OG-CG2 3.25Å; S123-V125 WeakPolarHBondContact OG-CG2 3.27Å; S123-K134 PolarHBondContact O-NZ 2.93Å; S123-L559 VanDerWaalsContact CB-CD2 3.43Å
124	G	83.1	Confident	90.3	Very high	34 Å²	34	15.1 Å²	15.1	35%	0.351	8%	0.082	S	C	.	.	T	Hydrogen-bonded Turn	trans	62.3	41.5	-179.9	0	0	0	0	0	112.2	Y120 I121 K122 K134	Y120-G124 PolarHBondContact O-N 3.2Å; I121-G124 PolarHBondContact O-N 3.47Å; I121-G124 VanDerWaalsContact O-N 3.1Å; K122-G124 VanDerWaalsContact C-N 3.25Å; K122-G124 PolarHBondContact O-N 3.1Å; G124-K134 PolarHBondContact O-NZ 3.26Å
125	V	84.6	Confident	90.2	Very high	8 Å²	8	12.3 Å²	12.3	5%	0.048	7%	0.072	C	C	.	.			trans	-99.7	155.5	-178.9	-63.5	0	0	0	0	111.1	S123 M128 E130 K134	S123-V125 VanDerWaalsContact C-N 3.35Å; S123-V125 VanDerWaalsContact OG-CG1 3.22Å; S123-V125 WeakPolarHBondContact OG-CG1 3.35Å; S123-V125 VanDerWaalsContact OG-CG2 3.25Å; S123-V125 WeakPolarHBondContact OG-CG2 3.27Å; V125-M128 HydrophobicContact CG2-CE 4.43Å; V125-E130 HydrophobicContact CG1-CG 4.24Å; V125-K134 HydrophobicContact CG1-CD 3.71Å
126	T	79.1	Confident	90	Very high	36 Å²	36	10.7 Å²	10.7	22%	0.221	6%	0.063	C	C	.	.	S	Bend	trans	-107	-32.4	172.9	60.9	0	0	0	0	111.7	L60 E130 Q295	L60-T126 HydrophobicContact CD1-CG2 4.08Å; T126-E130 PolarHBondContact N-OE2 2Å; T126-E130 PolarHBondContact OG1-OE2 2.93Å; T126-Q295 PolarHBondContact O-NE2 3.24Å; T126-Q295 VanDerWaalsContact O-NE2 3.14Å
127	T	86.7	Confident	89.5	Confident	0 Å²	0	10.8 Å²	10.8	0%	0	7%	0.065	C	C	.	.	S	Bend	trans	-118.7	152.6	178.7	79	0	0	0	0	112.7	E130 Y131 Q295 T403 I407 D408	T127-E130 PolarHBondContact N-OE2 3.18Å; T127-E130 WeakPolarHBondContact O-CB 3.39Å; T127-E130 PolarHBondContact O-N 2.72Å; T127-E130 WeakPolarHBondContact OG1-CB 3.38Å; T127-E130 PolarHBondContact OG1-N 2.92Å; T127-E130 VanDerWaalsContact OG1-N 3.08Å; T127-Y131 PolarHBondContact O-N 2.7Å; T127-Q295 VanDerWaalsContact CA-OE1 3.31Å; T127-T403 HydrophobicContact CG2-CG2 4.01Å; T127-I407 HydrophobicContact CG2-CB 4.25Å; T127-I407 HydrophobicContact CG2-CD1 4.24Å; T127-I407 HydrophobicContact CG2-CG2 4.15Å; T127-D408 PolarHBondContact OG1-OD1 3.25Å; T127-D408 PolarHBondContact OG1-OD2 2.88Å
128	M	90.5	Very high	88.8	Confident	3 Å²	3	12.5 Å²	12.5	2%	0.015	8%	0.083	C	C	.	.	H	α-helix	trans	-66.5	-40.5	175.9	-62.3	-60.8	102.6	0	0	112.2	Y120 V125 E130 Y131 L132 T293 V298 L302 Y471	Y120-M128 HydrophobicContact CD1-SD 4.47Å; Y120-M128 HydrophobicContact CD2-CE 4.25Å; Y120-M128 HydrophobicContact CD2-SD 4.09Å; Y120-M128 HydrophobicContact CE1-SD 4.16Å; Y120-M128 HydrophobicContact CE2-CE 4.49Å; Y120-M128 HydrophobicContact CE2-SD 3.74Å; Y120-M128 HydrophobicContact CG-CE 4.29Å; Y120-M128 HydrophobicContact CG-SD 4.43Å; V125-M128 HydrophobicContact CG2-CE 4.43Å; M128-E130 VanDerWaalsContact C-N 3.33Å; M128-E130 PolarHBondContact O-N 3.38Å; M128-Y131 WeakPolarHBondContact O-CB 3.37Å; M128-Y131 PolarHBondContact O-N 3.04Å; M128-L132 PolarHBondContact O-N 2.89Å; M128-T293 WeakPolarHBondContact CG-O 3.48Å; M128-V298 HydrophobicContact CE-CB 3.97Å; M128-V298 HydrophobicContact CE-CG1 3.33Å; M128-V298 HydrophobicContact CG-CB 4.35Å; M128-V298 HydrophobicContact SD-CB 3.84Å; M128-V298 HydrophobicContact SD-CG1 3.57Å; M128-V298 VanDerWaalsContact SD-CG1 3.57Å; M128-V298 HydrophobicContact SD-CG2 4Å; M128-L302 HydrophobicContact CE-CD1 4.13Å; M128-Y471 HydrophobicContact CB-CE1 4.32Å; M128-Y471 VanDerWaalsContact CB-OH 3.31Å; M128-Y471 WeakPolarHBondContact CB-OH 3.22Å; M128-Y471 PolarHBondContact O-OH 2.92Å
129	P	90	Very high	88.2	Confident	3 Å²	3	15.5 Å²	15.5	2%	0.019	10%	0.095	C	C	.	.	H	α-helix	trans	-61.2	-37	171.1	-27.5	38.8	0	0	0	113.4	Y131 L132 K133 Q142 L145 S146 L404	P129-Y131 VanDerWaalsContact C-N 3.32Å; P129-Y131 PolarHBondContact O-N 2.63Å; P129-L132 PolarHBondContact O-N 2.82Å; P129-L132 VanDerWaalsContact O-N 3.1Å; P129-K133 PolarHBondContact O-N 3.44Å; P129-Q142 HydrophobicContact CB-CB 4.36Å; P129-Q142 HydrophobicContact CB-CG 3.59Å; P129-L145 HydrophobicContact CB-CB 4.31Å; P129-L145 HydrophobicContact CG-CB 4.12Å; P129-S146 WeakPolarHBondContact CG-OG 3.43Å; P129-L404 HydrophobicContact CG-CD2 3.93Å
130	E	86.9	Confident	87.9	Confident	35 Å²	35	24 Å²	24	16%	0.164	13%	0.127	C	C	.	.	H	α-helix	trans	-61.2	-38.9	174.9	-172.3	-157.4	152.1	0	0	111.8	V125 T126 T127 M128 L132 K133 K134	V125-E130 HydrophobicContact CG1-CG 4.24Å; T126-E130 PolarHBondContact N-OE2 2Å; T126-E130 PolarHBondContact OG1-OE2 2.93Å; T127-E130 PolarHBondContact N-OE2 3.18Å; T127-E130 WeakPolarHBondContact O-CB 3.39Å; T127-E130 PolarHBondContact O-N 2.72Å; T127-E130 WeakPolarHBondContact OG1-CB 3.38Å; T127-E130 PolarHBondContact OG1-N 2.92Å; T127-E130 VanDerWaalsContact OG1-N 3.08Å; M128-E130 VanDerWaalsContact C-N 3.33Å; M128-E130 PolarHBondContact O-N 3.38Å; E130-L132 VanDerWaalsContact C-N 3.29Å; E130-L132 PolarHBondContact O-N 3.24Å; E130-K133 PolarHBondContact O-N 2.97Å; E130-K134 PolarHBondContact O-N 3.28Å; E130-K134 WeakPolarHBondContact OE1-CE 3.22Å; E130-K134 IonicContact OE1-NZ 2.66Å; E130-K134 PolarHBondContact OE1-NZ 3.39Å
131	Y	92.3	Very high	87.6	Confident	0 Å²	0	24 Å²	24	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-56.6	-43.6	171.9	168.5	-104.1	0	0	0	112.3	I119 Y120 T127 M128 P129 K134 R135 Y471 A474 I475 L559	I119-Y131 HydrophobicContact CG2-CE2 3.72Å; Y120-Y131 HydrophobicContact CD1-CD1 4.27Å; Y120-Y131 AromaticContact CD1-CD2 3.89Å; Y120-Y131 HydrophobicContact CD1-CD2 3.89Å; Y120-Y131 HydrophobicContact CD1-CE2 4.23Å; Y120-Y131 AromaticContact CD1-CG 3.93Å; Y120-Y131 HydrophobicContact CD1-CG 3.93Å; Y120-Y131 AromaticContact CE1-CD1 3.7Å; Y120-Y131 HydrophobicContact CE1-CD1 3.7Å; Y120-Y131 HydrophobicContact CE1-CD2 4.13Å; Y120-Y131 AromaticContact CE1-CE1 3.87Å; Y120-Y131 HydrophobicContact CE1-CE1 3.87Å; Y120-Y131 HydrophobicContact CE1-CE2 4.31Å; Y120-Y131 AromaticContact CE1-CG 3.83Å; Y120-Y131 HydrophobicContact CE1-CG 3.83Å; T127-Y131 PolarHBondContact O-N 2.7Å; M128-Y131 WeakPolarHBondContact O-CB 3.37Å; M128-Y131 PolarHBondContact O-N 3.04Å; P129-Y131 VanDerWaalsContact C-N 3.32Å; P129-Y131 PolarHBondContact O-N 2.63Å; Y131-K134 PolarHBondContact O-N 3.38Å; Y131-R135 VanDerWaalsContact O-CB 3.27Å; Y131-R135 WeakPolarHBondContact O-CB 3.25Å; Y131-R135 PolarHBondContact O-N 3.08Å; Y131-Y471 HydrophobicContact CD1-CD1 4.09Å; Y131-Y471 AromaticContact CD1-CE1 3.69Å; Y131-Y471 HydrophobicContact CD1-CE1 3.69Å; Y131-Y471 HydrophobicContact CE1-CD1 4.14Å; Y131-Y471 HydrophobicContact CE1-CE1 4.22Å; Y131-A474 HydrophobicContact CE1-CB 4.08Å; Y131-I475 HydrophobicContact CE1-CG1 4.48Å; Y131-I475 WeakPolarHBondContact OH-CG1 3.33Å; Y131-L559 HydrophobicContact CE2-CD2 4.43Å; Y131-L559 PolarHBondContact OH-O 3.09Å
132	L	92.3	Very high	87.4	Confident	0 Å²	0	24.3 Å²	24.3	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-72.9	-32.6	178.8	-68.8	-174.7	0	0	0	112.8	M128 P129 E130 R135 F136 L141 L145 V470 Y471 A474	M128-L132 PolarHBondContact O-N 2.89Å; P129-L132 PolarHBondContact O-N 2.82Å; P129-L132 VanDerWaalsContact O-N 3.1Å; E130-L132 VanDerWaalsContact C-N 3.29Å; E130-L132 PolarHBondContact O-N 3.24Å; L132-R135 PolarHBondContact O-N 2.68Å; L132-F136 HydrophobicContact CB-CD2 4.48Å; L132-F136 HydrophobicContact CD2-CD2 4.03Å; L132-F136 HydrophobicContact CD2-CE2 3.71Å; L132-F136 PolarHBondContact O-N 2.99Å; L132-L141 HydrophobicContact CB-CD2 3.9Å; L132-L141 HydrophobicContact CB-CG 4.42Å; L132-L141 HydrophobicContact CD1-CD2 4.47Å; L132-L145 HydrophobicContact CB-CD1 4.32Å; L132-L145 HydrophobicContact CD1-CD1 3.21Å; L132-L145 HydrophobicContact CG-CD1 4.28Å; L132-V470 HydrophobicContact CD1-CG1 3.97Å; L132-V470 HydrophobicContact CD2-CG1 4.44Å; L132-Y471 HydrophobicContact CD1-CD2 4.02Å; L132-Y471 HydrophobicContact CD1-CE1 4.11Å; L132-Y471 HydrophobicContact CD1-CE2 3.4Å; L132-Y471 VanDerWaalsContact CD1-CZ 3.43Å; L132-Y471 WeakPolarHBondContact CD1-OH 3.39Å; L132-Y471 HydrophobicContact CD2-CD1 4.47Å; L132-Y471 HydrophobicContact CD2-CE1 4.27Å; L132-Y471 HydrophobicContact CG-CE1 3.98Å; L132-Y471 HydrophobicContact CG-CE2 4.18Å; L132-A474 HydrophobicContact CD2-CB 3.69Å
133	K	89.7	Confident	87.4	Confident	29 Å²	29	25.1 Å²	25.1	13%	0.126	14%	0.136	C	C	.	.	H	α-helix	trans	-57.9	-50.2	168	-172.9	-177	-178	179.5	0	110.4	P129 E130 R135 G137 Q142 E577	P129-K133 PolarHBondContact O-N 3.44Å; E130-K133 PolarHBondContact O-N 2.97Å; K133-R135 VanDerWaalsContact C-N 3.32Å; K133-R135 PolarHBondContact O-N 2.89Å; K133-G137 WeakPolarHBondContact O-CA 3.28Å; K133-G137 PolarHBondContact O-N 3.06Å; K133-Q142 HydrophobicContact CB-CB 4.37Å; K133-E577 WeakPolarHBondContact CE-OE2 3.31Å; K133-E577 IonicContact NZ-OE2 3.72Å; K133-E577 PolarHBondContact NZ-OE2 3.39Å
134	K	89.7	Confident	87.6	Confident	11 Å²	11	26.3 Å²	26.3	5%	0.048	14%	0.14	C	C	.	.	H	α-helix	trans	-62.8	-38	177.5	-76.7	177.9	175.9	156	0	112.4	S123 G124 V125 E130 Y131 L559	S123-K134 PolarHBondContact O-NZ 2.93Å; G124-K134 PolarHBondContact O-NZ 3.26Å; V125-K134 HydrophobicContact CG1-CD 3.71Å; E130-K134 PolarHBondContact O-N 3.28Å; E130-K134 WeakPolarHBondContact OE1-CE 3.22Å; E130-K134 IonicContact OE1-NZ 2.66Å; E130-K134 PolarHBondContact OE1-NZ 3.39Å; Y131-K134 PolarHBondContact O-N 3.38Å; K134-L559 HydrophobicContact CB-CD1 4.21Å; K134-L559 HydrophobicContact CB-CD2 4.28Å; K134-L559 VanDerWaalsContact O-CD1 3.28Å; K134-L559 WeakPolarHBondContact O-CD1 3.46Å
135	R	93.3	Very high	87.9	Confident	0 Å²	0	24.8 Å²	24.8	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-74.4	-39.3	-175.9	175.1	59.7	-173.3	82.3	1.5	113.7	Y131 L132 K133 A474 C477 K478 V480	Y131-R135 VanDerWaalsContact O-CB 3.27Å; Y131-R135 WeakPolarHBondContact O-CB 3.25Å; Y131-R135 PolarHBondContact O-N 3.08Å; L132-R135 PolarHBondContact O-N 2.68Å; K133-R135 VanDerWaalsContact C-N 3.32Å; K133-R135 PolarHBondContact O-N 2.89Å; R135-A474 HydrophobicContact CG-CB 4.09Å; R135-A474 PolarHBondContact NE-O 3.32Å; R135-C477 PolarHBondContact NH2-O 3.49Å; R135-K478 PolarHBondContact NH2-O 3.45Å; R135-V480 PolarHBondContact NH1-O 3.38Å; R135-V480 PolarHBondContact NH2-O 3.01Å
136	F	91.6	Very high	88.2	Confident	8 Å²	8	24.4 Å²	24.4	4%	0.035	12%	0.122	C	C	.	.	H	α-helix	trans	-115.8	-18.7	-172.2	-63.8	-50.6	0	0	0	113.8	L132 L141 V470 A474 V480 E482 A485 I551	L132-F136 HydrophobicContact CB-CD2 4.48Å; L132-F136 HydrophobicContact CD2-CD2 4.03Å; L132-F136 HydrophobicContact CD2-CE2 3.71Å; L132-F136 PolarHBondContact O-N 2.99Å; F136-L141 HydrophobicContact CB-CD2 4.26Å; F136-L141 HydrophobicContact CD2-CD2 3.53Å; F136-L141 HydrophobicContact CE2-CD2 4.34Å; F136-L141 HydrophobicContact CG-CD2 4.34Å; F136-V470 HydrophobicContact CE2-CG1 3.97Å; F136-A474 HydrophobicContact CE2-CB 3.88Å; F136-A474 HydrophobicContact CZ-CB 3.65Å; F136-V480 HydrophobicContact CE1-CB 3.98Å; F136-V480 HydrophobicContact CE1-CG1 3.56Å; F136-V480 WeakPolarHBondContact CE1-O 3.41Å; F136-V480 HydrophobicContact CZ-CB 4.3Å; F136-V480 HydrophobicContact CZ-CG1 3.61Å; F136-E482 HydrophobicContact CB-CB 4.01Å; F136-E482 HydrophobicContact CB-CG 4.47Å; F136-A485 HydrophobicContact CD2-CB 3.91Å; F136-A485 HydrophobicContact CE2-CB 3.72Å; F136-A485 HydrophobicContact CG-CB 4.48Å; F136-A485 HydrophobicContact CZ-CB 4.21Å; F136-I551 HydrophobicContact CD1-CD1 4.25Å
137	G	86.1	Confident	88.8	Confident	4 Å²	4	27.3 Å²	27.3	4%	0.041	14%	0.135	C	C	.	.			trans	79.5	178.8	-169.6	0	0	0	0	0	112.3	K133	K133-G137 WeakPolarHBondContact O-CA 3.28Å; K133-G137 PolarHBondContact O-N 3.06Å
138	G	79.4	Confident	89	Confident	37 Å²	37	27.9 Å²	27.9	38%	0.381	14%	0.138	S	C	.	.			trans	74	150.8	174.1	0	0	0	0	0	114.9
139	E	81.6	Confident	89	Confident	81 Å²	81	29.2 Å²	29.2	38%	0.379	15%	0.147	S	C	.	.	S	Bend	trans	-87.5	-23.6	-178.4	-60.7	-164.7	132.5	0	0	113.7	L141 Q142 V143 K412	E139-L141 PolarHBondContact O-N 3.47Å; E139-Q142 PolarHBondContact O-N 3.45Å; E139-V143 WeakPolarHBondContact O-CG2 3.21Å; E139-V143 PolarHBondContact O-N 3.16Å; E139-K412 PolarHBondContact O-NZ 2.94Å
140	R	89.2	Confident	89.1	Confident	179 Å²	179	29.8 Å²	29.8	68%	0.675	15%	0.15	S	C	*	.	H	α-helix	trans	-60.9	-46.2	-171.3	-63.6	178.1	-178.5	175.4	0.2	112	V143 Y144 F486	R140-V143 PolarHBondContact O-N 3.14Å; R140-Y144 VanDerWaalsContact O-CB 3.24Å; R140-Y144 WeakPolarHBondContact O-CB 3.48Å; R140-Y144 PolarHBondContact O-N 3.28Å; R140-F486 HydrophobicContact CB-CD2 4.33Å; R140-F486 HydrophobicContact CB-CE2 4.24Å
141	L	86.8	Confident	89.3	Confident	0 Å²	0	31.5 Å²	31.5	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-64.6	-42.8	-178.2	-176	62.8	0	0	0	112.1	L132 F136 E139 L145 A485 L489	L132-L141 HydrophobicContact CB-CD2 3.9Å; L132-L141 HydrophobicContact CB-CG 4.42Å; L132-L141 HydrophobicContact CD1-CD2 4.47Å; F136-L141 HydrophobicContact CB-CD2 4.26Å; F136-L141 HydrophobicContact CD2-CD2 3.53Å; F136-L141 HydrophobicContact CE2-CD2 4.34Å; F136-L141 HydrophobicContact CG-CD2 4.34Å; E139-L141 PolarHBondContact O-N 3.47Å; L141-L145 HydrophobicContact CD1-CD1 4.23Å; L141-L145 HydrophobicContact CD1-CG 4.47Å; L141-L145 HydrophobicContact CG-CD1 4.19Å; L141-L145 WeakPolarHBondContact O-CB 3.34Å; L141-L145 WeakPolarHBondContact O-CG 3.44Å; L141-L145 PolarHBondContact O-N 3.37Å; L141-A485 HydrophobicContact CD2-CB 4.19Å; L141-L489 HydrophobicContact CD1-CD1 3.3Å
142	Q	86.4	Confident	89.2	Confident	11 Å²	11	31.8 Å²	31.8	5%	0.051	16%	0.158	C	C	.	.	H	α-helix	trans	-64.2	-49.3	177.5	-173.3	-169.8	12.8	0	0	110.8	P129 K133 E139 Y144 L145 S146 D408	P129-Q142 HydrophobicContact CB-CB 4.36Å; P129-Q142 HydrophobicContact CB-CG 3.59Å; K133-Q142 HydrophobicContact CB-CB 4.37Å; E139-Q142 PolarHBondContact O-N 3.45Å; Q142-Y144 VanDerWaalsContact C-N 3.34Å; Q142-Y144 PolarHBondContact O-N 3.06Å; Q142-L145 PolarHBondContact O-N 3.35Å; Q142-S146 WeakPolarHBondContact O-CB 3.13Å; Q142-S146 PolarHBondContact O-N 2.94Å; Q142-S146 PolarHBondContact O-OG 2.72Å; Q142-D408 HydrophobicContact CG-CB 4.18Å; Q142-D408 PolarHBondContact NE2-OD1 3.31Å
143	V	89.6	Confident	89	Confident	46 Å²	46	32.1 Å²	32.1	28%	0.279	16%	0.161	S	C	.	.	H	α-helix	trans	-59	-47	178.2	173.7	0	0	0	0	110.9	E139 R140 L145 S146 I147 L409 K412	E139-V143 WeakPolarHBondContact O-CG2 3.21Å; E139-V143 PolarHBondContact O-N 3.16Å; R140-V143 PolarHBondContact O-N 3.14Å; V143-L145 PolarHBondContact O-N 3.01Å; V143-S146 PolarHBondContact O-N 3.49Å; V143-I147 HydrophobicContact CG1-CD1 3.64Å; V143-I147 HydrophobicContact CG1-CG1 4.34Å; V143-I147 WeakPolarHBondContact O-CG1 3.28Å; V143-I147 PolarHBondContact O-N 3.03Å; V143-L409 HydrophobicContact CB-CD2 4.48Å; V143-L409 HydrophobicContact CG1-CD2 4.07Å; V143-L409 HydrophobicContact CG2-CD2 4.46Å; V143-K412 HydrophobicContact CG2-CD 3.75Å
144	Y	90.9	Very high	88.9	Confident	28 Å²	28	31.2 Å²	31.2	11%	0.11	16%	0.158	C	C	.	.	H	α-helix	trans	-55.7	-50.4	178.1	167.8	-91.5	0	0	0	111.8	R140 Q142 I147 L148 L489 M490 L493	R140-Y144 VanDerWaalsContact O-CB 3.24Å; R140-Y144 WeakPolarHBondContact O-CB 3.48Å; R140-Y144 PolarHBondContact O-N 3.28Å; Q142-Y144 VanDerWaalsContact C-N 3.34Å; Q142-Y144 PolarHBondContact O-N 3.06Å; Y144-I147 PolarHBondContact O-N 3.02Å; Y144-L148 HydrophobicContact CE1-CD2 3.93Å; Y144-L148 WeakPolarHBondContact O-CB 3.17Å; Y144-L148 PolarHBondContact O-N 3.22Å; Y144-L489 HydrophobicContact CD1-CB 4.38Å; Y144-L489 HydrophobicContact CD1-CD1 4.12Å; Y144-L489 HydrophobicContact CE1-CB 3.59Å; Y144-L489 HydrophobicContact CE1-CD1 3.85Å; Y144-L489 HydrophobicContact CE1-CD2 4.19Å; Y144-L489 HydrophobicContact CE1-CG 4.07Å; Y144-L489 PolarHBondContact OH-O 3.3Å; Y144-M490 HydrophobicContact CD2-SD 3.83Å; Y144-M490 HydrophobicContact CE2-SD 3.54Å; Y144-M490 VanDerWaalsContact CE2-SD 3.54Å; Y144-L493 HydrophobicContact CE2-CD2 3.64Å; Y144-L493 VanDerWaalsContact OH-CB 3.28Å; Y144-L493 WeakPolarHBondContact OH-CB 3.36Å; Y144-L493 WeakPolarHBondContact OH-CD2 3.49Å
145	L	90.3	Very high	88.6	Confident	2 Å²	2	30.8 Å²	30.8	1%	0.01	16%	0.156	C	C	.	.	H	α-helix	trans	-68.6	-37.1	-178.2	-73.7	172	0	0	0	112.8	P129 L132 L141 Q142 V143 S149 I467 L489	P129-L145 HydrophobicContact CB-CB 4.31Å; P129-L145 HydrophobicContact CG-CB 4.12Å; L132-L145 HydrophobicContact CB-CD1 4.32Å; L132-L145 HydrophobicContact CD1-CD1 3.21Å; L132-L145 HydrophobicContact CG-CD1 4.28Å; L141-L145 HydrophobicContact CD1-CD1 4.23Å; L141-L145 HydrophobicContact CD1-CG 4.47Å; L141-L145 HydrophobicContact CG-CD1 4.19Å; L141-L145 WeakPolarHBondContact O-CB 3.34Å; L141-L145 WeakPolarHBondContact O-CG 3.44Å; L141-L145 PolarHBondContact O-N 3.37Å; Q142-L145 PolarHBondContact O-N 3.35Å; V143-L145 PolarHBondContact O-N 3.01Å; L145-S149 WeakPolarHBondContact O-CB 3.4Å; L145-S149 PolarHBondContact O-N 2.76Å; L145-S149 PolarHBondContact O-OG 2.86Å; L145-I467 HydrophobicContact CD2-CG1 4.23Å; L145-I467 HydrophobicContact CD2-CG2 4.47Å; L145-L489 HydrophobicContact CD2-CD1 4.06Å; L145-L489 HydrophobicContact CD2-CD2 4.42Å; L145-L489 HydrophobicContact CG-CD1 4.45Å
146	S	89.9	Confident	88.2	Confident	0 Å²	0	30.9 Å²	30.9	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-65.5	-44.6	176.4	-57.2	0	0	0	0	110.7	P129 Q142 V143 S149 L150 D408	P129-S146 WeakPolarHBondContact CG-OG 3.43Å; Q142-S146 WeakPolarHBondContact O-CB 3.13Å; Q142-S146 PolarHBondContact O-N 2.94Å; Q142-S146 PolarHBondContact O-OG 2.72Å; V143-S146 PolarHBondContact O-N 3.49Å; S146-S149 PolarHBondContact O-N 2.74Å; S146-L150 WeakPolarHBondContact O-CB 3.44Å; S146-L150 WeakPolarHBondContact O-CG 3.31Å; S146-L150 PolarHBondContact O-N 3.39Å; S146-D408 WeakPolarHBondContact OG-CB 3.29Å; S146-D408 VanDerWaalsContact OG-CG 3.3Å; S146-D408 PolarHBondContact OG-OD2 3.04Å
147	I	91.9	Very high	87.9	Confident	96 Å²	96	31.5 Å²	31.5	49%	0.492	16%	0.16	S	C	.	.	H	α-helix	trans	-63.2	-47.3	175.8	-66.9	171.7	0	0	0	111.1	V143 Y144 S149 L150 F151 L409	V143-I147 HydrophobicContact CG1-CD1 3.64Å; V143-I147 HydrophobicContact CG1-CG1 4.34Å; V143-I147 WeakPolarHBondContact O-CG1 3.28Å; V143-I147 PolarHBondContact O-N 3.03Å; Y144-I147 PolarHBondContact O-N 3.02Å; I147-S149 PolarHBondContact O-N 3.33Å; I147-L150 PolarHBondContact O-N 3.43Å; I147-F151 WeakPolarHBondContact O-CB 3.46Å; I147-F151 PolarHBondContact O-N 2.81Å; I147-L409 HydrophobicContact CG1-CD1 4.35Å; I147-L409 HydrophobicContact CG1-CD2 4.28Å
148	L	91.5	Very high	88	Confident	13 Å²	13	31.3 Å²	31.3	7%	0.068	16%	0.158	C	C	.	.	H	α-helix	trans	-63.5	-41.8	179.4	179.6	59.4	0	0	0	111.6	Y144 F151 I152 I467 L493	Y144-L148 HydrophobicContact CE1-CD2 3.93Å; Y144-L148 WeakPolarHBondContact O-CB 3.17Å; Y144-L148 PolarHBondContact O-N 3.22Å; L148-F151 HydrophobicContact CD1-CD1 4.46Å; L148-F151 WeakPolarHBondContact O-CB 3.46Å; L148-F151 PolarHBondContact O-N 3.23Å; L148-I152 HydrophobicContact CD1-CD1 4.13Å; L148-I152 HydrophobicContact CD1-CG1 4.31Å; L148-I152 HydrophobicContact CG-CD1 3.94Å; L148-I152 VanDerWaalsContact O-CG1 3.27Å; L148-I152 WeakPolarHBondContact O-CG1 3.45Å; L148-I152 PolarHBondContact O-N 3.07Å; L148-I467 HydrophobicContact CD2-CD1 3.85Å; L148-I467 HydrophobicContact CD2-CG1 4.2Å; L148-I467 HydrophobicContact CG-CD1 4.35Å; L148-L493 HydrophobicContact CD1-CD1 3.74Å; L148-L493 HydrophobicContact CD2-CD1 4.35Å
149	S	90.5	Very high	88.2	Confident	30 Å²	30	29.7 Å²	29.7	21%	0.21	14%	0.141	C	C	.	.	H	α-helix	trans	-64.6	-41.2	177.2	-59.6	0	0	0	0	111.4	L145 S146 I147 I152 C153	L145-S149 WeakPolarHBondContact O-CB 3.4Å; L145-S149 PolarHBondContact O-N 2.76Å; L145-S149 PolarHBondContact O-OG 2.86Å; S146-S149 PolarHBondContact O-N 2.74Å; I147-S149 PolarHBondContact O-N 3.33Å; S149-I152 PolarHBondContact O-N 3.04Å; S149-C153 WeakPolarHBondContact O-CB 3.47Å; S149-C153 PolarHBondContact O-N 3.33Å; S149-C153 PolarHBondContact O-SG 3.02Å
150	L	90.9	Very high	88.3	Confident	16 Å²	16	25.9 Å²	25.9	8%	0.084	12%	0.124	C	C	.	.	H	α-helix	trans	-62.9	-42.6	174.5	-73.1	172.3	0	0	0	111.9	S146 I147 C153 V154 A401 L404 L409 F429	S146-L150 WeakPolarHBondContact O-CB 3.44Å; S146-L150 WeakPolarHBondContact O-CG 3.31Å; S146-L150 PolarHBondContact O-N 3.39Å; I147-L150 PolarHBondContact O-N 3.43Å; L150-C153 WeakPolarHBondContact O-CB 3.26Å; L150-C153 PolarHBondContact O-N 2.89Å; L150-V154 PolarHBondContact O-N 2.88Å; L150-A401 HydrophobicContact CD2-CB 3.62Å; L150-L404 HydrophobicContact CD2-CB 4.32Å; L150-L404 HydrophobicContact CG-CB 4.49Å; L150-L409 HydrophobicContact CD1-CD1 3.71Å; L150-F429 HydrophobicContact CD1-CE1 4.41Å; L150-F429 HydrophobicContact CD1-CZ 3.88Å; L150-F429 HydrophobicContact CD2-CE1 3.7Å; L150-F429 HydrophobicContact CD2-CZ 3.85Å; L150-F429 HydrophobicContact CG-CZ 4.43Å
151	F	90.8	Very high	88.3	Confident	71 Å²	71	18 Å²	18	31%	0.311	10%	0.095	S	C	.	.	H	α-helix	trans	-59.7	-48.6	173.9	174.6	-101.2	0	0	0	111.3	I147 L148 C153 V154 V155 L463 M500	I147-F151 WeakPolarHBondContact O-CB 3.46Å; I147-F151 PolarHBondContact O-N 2.81Å; L148-F151 HydrophobicContact CD1-CD1 4.46Å; L148-F151 WeakPolarHBondContact O-CB 3.46Å; L148-F151 PolarHBondContact O-N 3.23Å; F151-C153 VanDerWaalsContact C-N 3.33Å; F151-C153 PolarHBondContact O-N 3.38Å; F151-V154 PolarHBondContact O-N 3.36Å; F151-V155 HydrophobicContact CD1-CG2 4.48Å; F151-V155 HydrophobicContact CD2-CG2 3.98Å; F151-V155 HydrophobicContact CE1-CG2 4.1Å; F151-V155 HydrophobicContact CE2-CG2 3.55Å; F151-V155 HydrophobicContact CG-CG2 4.43Å; F151-V155 HydrophobicContact CZ-CG2 3.62Å; F151-V155 WeakPolarHBondContact O-CG2 3.46Å; F151-V155 PolarHBondContact O-N 2.99Å; F151-L463 HydrophobicContact CD1-CD1 4.27Å; F151-L463 HydrophobicContact CE1-CD1 3.92Å; F151-M500 HydrophobicContact CZ-CE 4.32Å
152	I	90.4	Very high	88.1	Confident	5 Å²	5	18 Å²	18	3%	0.026	10%	0.095	C	C	.	.	H	α-helix	trans	-61.2	-41.7	176.8	-65.1	163.4	0	0	0	110.8	L148 S149 V154 V155 L156 W289 L463 I467	L148-I152 HydrophobicContact CD1-CD1 4.13Å; L148-I152 HydrophobicContact CD1-CG1 4.31Å; L148-I152 HydrophobicContact CG-CD1 3.94Å; L148-I152 VanDerWaalsContact O-CG1 3.27Å; L148-I152 WeakPolarHBondContact O-CG1 3.45Å; L148-I152 PolarHBondContact O-N 3.07Å; S149-I152 PolarHBondContact O-N 3.04Å; I152-V154 VanDerWaalsContact C-N 3.26Å; I152-V154 PolarHBondContact O-N 2.75Å; I152-V155 PolarHBondContact O-N 3.23Å; I152-L156 HydrophobicContact CG2-CB 3.96Å; I152-L156 HydrophobicContact CG2-CD2 3.84Å; I152-L156 WeakPolarHBondContact O-CA 3.36Å; I152-L156 WeakPolarHBondContact O-CB 3.41Å; I152-L156 PolarHBondContact O-N 3.45Å; I152-W289 HydrophobicContact CD1-CZ2 4.03Å; I152-W289 HydrophobicContact CG2-CH2 3.68Å; I152-W289 HydrophobicContact CG2-CZ2 3.67Å; I152-L463 HydrophobicContact CD1-CB 3.92Å; I152-L463 HydrophobicContact CG1-CB 4.12Å; I152-L463 HydrophobicContact CG1-CD1 3.8Å; I152-I467 HydrophobicContact CD1-CD1 4.02Å
153	C	88.7	Confident	87.9	Confident	7 Å²	7	18.7 Å²	18.7	5%	0.047	10%	0.098	C	C	.	.	I	π-helix	trans	-54.5	-42.6	176.2	-74.9	0	0	0	0	112.2	S149 L150 F151 L157 I158 I397	S149-C153 WeakPolarHBondContact O-CB 3.47Å; S149-C153 PolarHBondContact O-N 3.33Å; S149-C153 PolarHBondContact O-SG 3.02Å; L150-C153 WeakPolarHBondContact O-CB 3.26Å; L150-C153 PolarHBondContact O-N 2.89Å; F151-C153 VanDerWaalsContact C-N 3.33Å; F151-C153 PolarHBondContact O-N 3.38Å; C153-L157 PolarHBondContact O-N 3.16Å; C153-I158 VanDerWaalsContact O-CG1 3.3Å; C153-I158 WeakPolarHBondContact O-CG1 3.46Å; C153-I158 PolarHBondContact O-N 3.4Å; C153-I397 HydrophobicContact CB-CG2 3.99Å
154	V	86.8	Confident	87.7	Confident	11 Å²	11	16.5 Å²	16.5	7%	0.067	9%	0.085	C	C	.	.	I	π-helix	trans	-70.2	-56.3	178.5	175.7	0	0	0	0	111.4	L150 F151 I152 L156 I158 A159 L433 V436 W440	L150-V154 PolarHBondContact O-N 2.88Å; F151-V154 PolarHBondContact O-N 3.36Å; I152-V154 VanDerWaalsContact C-N 3.26Å; I152-V154 PolarHBondContact O-N 2.75Å; V154-L156 PolarHBondContact O-N 3.15Å; V154-I158 HydrophobicContact CG2-CD1 4.34Å; V154-A159 WeakPolarHBondContact O-CB 3.47Å; V154-A159 PolarHBondContact O-N 3.31Å; V154-L433 HydrophobicContact CG2-CD1 3.38Å; V154-L433 HydrophobicContact CG2-CG 4.34Å; V154-V436 HydrophobicContact CG1-CG1 4.16Å; V154-W440 HydrophobicContact CG1-CB 4.43Å; V154-W440 HydrophobicContact CG1-CG 4.4Å
155	V	83.8	Confident	87.3	Confident	1 Å²	1	15.2 Å²	15.2	1%	0.006	8%	0.079	C	C	.	.	I	π-helix	trans	-72.1	-33	-168.5	177.9	0	0	0	0	112.4	F151 I152 A159 W440 Y455 I459	F151-V155 HydrophobicContact CD1-CG2 4.48Å; F151-V155 HydrophobicContact CD2-CG2 3.98Å; F151-V155 HydrophobicContact CE1-CG2 4.1Å; F151-V155 HydrophobicContact CE2-CG2 3.55Å; F151-V155 HydrophobicContact CG-CG2 4.43Å; F151-V155 HydrophobicContact CZ-CG2 3.62Å; F151-V155 WeakPolarHBondContact O-CG2 3.46Å; F151-V155 PolarHBondContact O-N 2.99Å; I152-V155 PolarHBondContact O-N 3.23Å; V155-A159 WeakPolarHBondContact O-CB 3.39Å; V155-W440 HydrophobicContact CB-CZ2 4.21Å; V155-W440 HydrophobicContact CG1-CZ2 3.88Å; V155-W440 HydrophobicContact CG2-CD2 4.35Å; V155-W440 HydrophobicContact CG2-CH2 4.01Å; V155-W440 HydrophobicContact CG2-CZ2 3.4Å; V155-Y455 PolarHBondContact O-OH 3.48Å; V155-Y455 VanDerWaalsContact O-OH 3.13Å; V155-I459 HydrophobicContact CG1-CD1 4.21Å
156	L	84.9	Confident	86.9	Confident	2 Å²	2	15.1 Å²	15.1	1%	0.01	8%	0.079	C	C	.	.	I	π-helix	trans	-100	-63.6	-175.6	-177.7	69.7	0	0	0	112	I152 V154 S160 W289 T456 I459 S460	I152-L156 HydrophobicContact CG2-CB 3.96Å; I152-L156 HydrophobicContact CG2-CD2 3.84Å; I152-L156 WeakPolarHBondContact O-CA 3.36Å; I152-L156 WeakPolarHBondContact O-CB 3.41Å; I152-L156 PolarHBondContact O-N 3.45Å; V154-L156 PolarHBondContact O-N 3.15Å; L156-S160 WeakPolarHBondContact O-CB 3.28Å; L156-S160 PolarHBondContact O-N 3.14Å; L156-W289 HydrophobicContact CD2-CH2 3.61Å; L156-W289 HydrophobicContact CD2-CZ3 4.03Å; L156-T456 HydrophobicContact CD1-CG2 3.45Å; L156-T456 VanDerWaalsContact CD1-CG2 3.45Å; L156-T456 WeakPolarHBondContact CD1-O 3.39Å; L156-T456 HydrophobicContact CG-CG2 4.14Å; L156-I459 HydrophobicContact CB-CG2 4.34Å; L156-I459 HydrophobicContact CD1-CB 4.01Å; L156-I459 HydrophobicContact CD1-CG2 4.05Å; L156-S460 VanDerWaalsContact CD2-OG 3.26Å; L156-S460 WeakPolarHBondContact CD2-OG 3.35Å
157	L	86.3	Confident	86.4	Confident	21 Å²	21	15.2 Å²	15.2	11%	0.11	8%	0.079	C	C	.	.	I	π-helix	trans	-78.4	-57	-165.1	-56	178.9	0	0	0	111.1	C153 S160 D161 Y290 I397	C153-L157 PolarHBondContact O-N 3.16Å; L157-S160 PolarHBondContact O-N 2.74Å; L157-D161 WeakPolarHBondContact O-CB 3.42Å; L157-D161 PolarHBondContact O-N 3.15Å; L157-Y290 HydrophobicContact CD2-CE2 4.38Å; L157-I397 HydrophobicContact CB-CD1 3.56Å; L157-I397 HydrophobicContact CB-CG1 4.04Å; L157-I397 HydrophobicContact CB-CG2 4.35Å; L157-I397 HydrophobicContact CD1-CG1 4.18Å; L157-I397 HydrophobicContact CD1-CG2 4.46Å
158	I	87.2	Confident	85.8	Confident	0 Å²	0	10.8 Å²	10.8	0%	0	6%	0.057	C	C	.	.	I	π-helix	trans	-64.9	-47.9	-175.3	-63.5	160.3	0	0	0	110.8	C153 V154 S160 D161 M162 L394 I397 F398 L433 S437	C153-I158 VanDerWaalsContact O-CG1 3.3Å; C153-I158 WeakPolarHBondContact O-CG1 3.46Å; C153-I158 PolarHBondContact O-N 3.4Å; V154-I158 HydrophobicContact CG2-CD1 4.34Å; I158-S160 PolarHBondContact O-N 3.43Å; I158-D161 PolarHBondContact O-N 3.33Å; I158-M162 HydrophobicContact CG2-CG 4.01Å; I158-M162 HydrophobicContact CG2-SD 3.32Å; I158-M162 WeakPolarHBondContact CG2-SD 3.5Å; I158-M162 VanDerWaalsContact O-CB 3.28Å; I158-M162 WeakPolarHBondContact O-CB 3.43Å; I158-M162 WeakPolarHBondContact O-CG 3.48Å; I158-M162 PolarHBondContact O-N 3.26Å; I158-L394 HydrophobicContact CB-CD2 4.48Å; I158-L394 HydrophobicContact CG2-CD2 4.07Å; I158-I397 HydrophobicContact CD1-CG2 3.92Å; I158-I397 HydrophobicContact CG1-CB 4.36Å; I158-I397 HydrophobicContact CG1-CD1 4.43Å; I158-I397 HydrophobicContact CG1-CG2 3.61Å; I158-F398 HydrophobicContact CD1-CD1 4.02Å; I158-F398 HydrophobicContact CD1-CE1 3.59Å; I158-F398 HydrophobicContact CG1-CD1 4.41Å; I158-F398 HydrophobicContact CG1-CE1 3.92Å; I158-F398 HydrophobicContact CG2-CE1 4.29Å; I158-L433 HydrophobicContact CD1-CD2 3.86Å; I158-L433 HydrophobicContact CD1-CG 4.03Å; I158-S437 VanDerWaalsContact CG2-CB 3.5Å; I158-S437 WeakPolarHBondContact CG2-OG 3.4Å
159	A	84	Confident	85.2	Confident	4 Å²	4	10.7 Å²	10.7	3%	0.033	6%	0.056	C	C	.	.	H	α-helix	trans	-54.1	-49.1	177.7	0	0	0	0	0	113.3	V154 V155 F163 V444	V154-A159 WeakPolarHBondContact O-CB 3.47Å; V154-A159 PolarHBondContact O-N 3.31Å; V155-A159 WeakPolarHBondContact O-CB 3.39Å; A159-F163 WeakPolarHBondContact O-CB 3.37Å; A159-F163 PolarHBondContact O-N 3.41Å; A159-F163 VanDerWaalsContact O-N 3.07Å; A159-V444 HydrophobicContact CB-CG1 4.45Å; A159-V444 HydrophobicContact CB-CG2 3.53Å
160	S	84.6	Confident	84.6	Confident	1 Å²	1	12.9 Å²	12.9	1%	0.007	6%	0.062	C	C	.	.	H	α-helix	trans	-68.5	-45.3	-177	-170.3	0	0	0	0	111.9	N82 L156 L157 I158 F163 A164 L452 T456	N82-S160 PolarHBondContact ND2-OG 3.29Å; N82-S160 VanDerWaalsContact ND2-OG 3.17Å; N82-S160 PolarHBondContact OD1-OG 3.39Å; N82-S160 VanDerWaalsContact OD1-OG 3.11Å; L156-S160 WeakPolarHBondContact O-CB 3.28Å; L156-S160 PolarHBondContact O-N 3.14Å; L157-S160 PolarHBondContact O-N 2.74Å; I158-S160 PolarHBondContact O-N 3.43Å; S160-F163 PolarHBondContact O-N 3.42Å; S160-A164 WeakPolarHBondContact O-CB 3.44Å; S160-A164 PolarHBondContact O-N 3.42Å; S160-L452 VanDerWaalsContact OG-CD1 3.3Å; S160-L452 WeakPolarHBondContact OG-CD1 3.3Å; S160-T456 PolarHBondContact OG-OG1 3.06Å; S160-T456 VanDerWaalsContact OG-OG1 3.12Å
161	D	87.3	Confident	83.9	Confident	13 Å²	13	13 Å²	13	7%	0.07	6%	0.062	C	C	.	.	H	α-helix	trans	-62.9	-46.3	175.9	-81.9	-47.5	0	0	0	111.8	N82 L157 I158 F163 A164 G165 L390 L394	N82-D161 WeakPolarHBondContact CB-OD1 3.28Å; L157-D161 WeakPolarHBondContact O-CB 3.42Å; L157-D161 PolarHBondContact O-N 3.15Å; I158-D161 PolarHBondContact O-N 3.33Å; D161-F163 VanDerWaalsContact C-N 3.34Å; D161-F163 PolarHBondContact O-N 3.36Å; D161-A164 PolarHBondContact O-N 3.11Å; D161-G165 PolarHBondContact O-N 3.2Å; D161-L390 HydrophobicContact CB-CD1 4.08Å; D161-L390 WeakPolarHBondContact O-CD1 3.46Å; D161-L394 HydrophobicContact CB-CD2 3.94Å; D161-L394 HydrophobicContact CB-CG 4.38Å
162	M	83.9	Confident	83.1	Confident	0 Å²	0	9.9 Å²	9.9	0%	0	5%	0.05	C	C	.	.	H	α-helix	trans	-59.1	-44.3	178.2	-74.7	172.5	64.8	0	0	112.1	I158 G165 A166 I181 L185 L394 I438 V441	I158-M162 HydrophobicContact CG2-CG 4.01Å; I158-M162 HydrophobicContact CG2-SD 3.32Å; I158-M162 WeakPolarHBondContact CG2-SD 3.5Å; I158-M162 VanDerWaalsContact O-CB 3.28Å; I158-M162 WeakPolarHBondContact O-CB 3.43Å; I158-M162 WeakPolarHBondContact O-CG 3.48Å; I158-M162 PolarHBondContact O-N 3.26Å; M162-G165 PolarHBondContact O-N 3.17Å; M162-A166 VanDerWaalsContact O-CB 3.23Å; M162-A166 WeakPolarHBondContact O-CB 3.48Å; M162-A166 PolarHBondContact O-N 3.4Å; M162-I181 HydrophobicContact CE-CB 4.43Å; M162-I181 HydrophobicContact CE-CG1 4.46Å; M162-I181 HydrophobicContact CE-CG2 3.27Å; M162-L185 HydrophobicContact CE-CD1 3.55Å; M162-L185 HydrophobicContact CE-CD2 4.34Å; M162-L185 HydrophobicContact CE-CG 4.15Å; M162-L185 HydrophobicContact CG-CD2 4.4Å; M162-L185 HydrophobicContact SD-CD1 4.26Å; M162-L185 HydrophobicContact SD-CD2 4.07Å; M162-L394 HydrophobicContact CG-CD1 4.41Å; M162-L394 HydrophobicContact CG-CD2 4.23Å; M162-I438 HydrophobicContact CE-CG1 4.36Å; M162-V441 HydrophobicContact CE-CG2 3.78Å
163	F	81.6	Confident	82.3	Confident	26 Å²	26	13.7 Å²	13.7	11%	0.114	7%	0.07	C	C	.	.	H	α-helix	trans	-63.8	-48.9	179.5	178.8	-98.7	0	0	0	111.8	A159 S160 D161 G165 A166 I167 V444 Q445 L452	A159-F163 WeakPolarHBondContact O-CB 3.37Å; A159-F163 PolarHBondContact O-N 3.41Å; A159-F163 VanDerWaalsContact O-N 3.07Å; S160-F163 PolarHBondContact O-N 3.42Å; D161-F163 VanDerWaalsContact C-N 3.34Å; D161-F163 PolarHBondContact O-N 3.36Å; F163-G165 VanDerWaalsContact C-N 3.31Å; F163-G165 PolarHBondContact O-N 3.03Å; F163-A166 PolarHBondContact O-N 3.42Å; F163-I167 HydrophobicContact CD1-CD1 3.98Å; F163-I167 HydrophobicContact CE1-CD1 3.42Å; F163-I167 VanDerWaalsContact CE1-CD1 3.42Å; F163-I167 HydrophobicContact CE1-CG1 4.32Å; F163-I167 HydrophobicContact CZ-CD1 3.82Å; F163-I167 HydrophobicContact CZ-CG1 4.41Å; F163-I167 PolarHBondContact O-N 3.23Å; F163-V444 HydrophobicContact CB-CG1 4.38Å; F163-Q445 HydrophobicContact CD2-CG 4.44Å; F163-Q445 HydrophobicContact CE2-CG 4.27Å; F163-L452 HydrophobicContact CD1-CD1 4.09Å; F163-L452 HydrophobicContact CD1-CD2 4.36Å
164	A	85.1	Confident	81.6	Confident	0 Å²	0	15.7 Å²	15.7	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-59.4	-43.8	176.6	0	0	0	0	0	112.2	N82 V85 S160 D161 A166 I167 F168 L452	N82-A164 VanDerWaalsContact CA-CB 3.41Å; N82-A164 HydrophobicContact CB-CB 4.11Å; V85-A164 HydrophobicContact CB-CB 3.91Å; V85-A164 HydrophobicContact CG1-CB 4.33Å; V85-A164 HydrophobicContact CG2-CB 3.7Å; S160-A164 WeakPolarHBondContact O-CB 3.44Å; S160-A164 PolarHBondContact O-N 3.42Å; D161-A164 PolarHBondContact O-N 3.11Å; A164-A166 VanDerWaalsContact C-N 3.34Å; A164-A166 PolarHBondContact O-N 3.47Å; A164-I167 PolarHBondContact O-N 3.43Å; A164-F168 WeakPolarHBondContact O-CD2 3.18Å; A164-F168 PolarHBondContact O-N 3.08Å; A164-L452 HydrophobicContact CB-CD2 3.82Å
165	G	83.9	Confident	81	Confident	0 Å²	0	17.7 Å²	17.7	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-61	-40.9	175.2	0	0	0	0	0	113.8	D161 M162 F163 F168 I169	D161-G165 PolarHBondContact O-N 3.2Å; M162-G165 PolarHBondContact O-N 3.17Å; F163-G165 VanDerWaalsContact C-N 3.31Å; F163-G165 PolarHBondContact O-N 3.03Å; G165-F168 WeakPolarHBondContact O-CB 3.32Å; G165-F168 PolarHBondContact O-N 3.27Å; G165-I169 WeakPolarHBondContact O-CG1 3.34Å; G165-I169 PolarHBondContact O-N 3.12Å
166	A	81.2	Confident	80.9	Confident	0 Å²	0	22.5 Å²	22.5	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-68.2	-34.6	179.1	0	0	0	0	0	112.2	M162 F163 A164 F168 I169 K170 L177 I181	M162-A166 VanDerWaalsContact O-CB 3.23Å; M162-A166 WeakPolarHBondContact O-CB 3.48Å; M162-A166 PolarHBondContact O-N 3.4Å; F163-A166 PolarHBondContact O-N 3.42Å; A164-A166 VanDerWaalsContact C-N 3.34Å; A164-A166 PolarHBondContact O-N 3.47Å; A166-F168 VanDerWaalsContact C-N 3.33Å; A166-F168 PolarHBondContact O-N 3.22Å; A166-I169 PolarHBondContact O-N 3.05Å; A166-K170 WeakPolarHBondContact O-CB 3.17Å; A166-K170 PolarHBondContact O-N 3.14Å; A166-L177 HydrophobicContact CB-CD1 3.32Å; A166-L177 HydrophobicContact CB-CG 3.92Å; A166-I181 HydrophobicContact CB-CD1 4.06Å; A166-I181 HydrophobicContact CB-CG1 3.75Å
167	I	79.6	Confident	80.3	Confident	2 Å²	2	23.1 Å²	23.1	1%	0.01	13%	0.131	C	C	.	.	H	α-helix	trans	-57.7	-47.2	169.6	-70.6	171.6	0	0	0	110.4	V85 F163 A164 K170 L171 N363 Y364 P367	V85-I167 HydrophobicContact CG1-CD1 3.9Å; F163-I167 HydrophobicContact CD1-CD1 3.98Å; F163-I167 HydrophobicContact CE1-CD1 3.42Å; F163-I167 VanDerWaalsContact CE1-CD1 3.42Å; F163-I167 HydrophobicContact CE1-CG1 4.32Å; F163-I167 HydrophobicContact CZ-CD1 3.82Å; F163-I167 HydrophobicContact CZ-CG1 4.41Å; F163-I167 PolarHBondContact O-N 3.23Å; A164-I167 PolarHBondContact O-N 3.43Å; I167-K170 PolarHBondContact O-N 3.22Å; I167-L171 HydrophobicContact CG2-CD1 3.76Å; I167-L171 HydrophobicContact CG2-CG 4.46Å; I167-L171 WeakPolarHBondContact O-CB 3.11Å; I167-L171 WeakPolarHBondContact O-CG 3.35Å; I167-L171 PolarHBondContact O-N 3.2Å; I167-N363 HydrophobicContact CD1-CB 4.14Å; I167-Y364 HydrophobicContact CB-CE2 4.38Å; I167-Y364 HydrophobicContact CD1-CD2 4.31Å; I167-Y364 HydrophobicContact CD1-CE2 3.81Å; I167-Y364 HydrophobicContact CG1-CE2 3.82Å; I167-Y364 HydrophobicContact CG2-CD2 3.92Å; I167-Y364 HydrophobicContact CG2-CE1 4.38Å; I167-Y364 HydrophobicContact CG2-CE2 3.69Å; I167-Y364 HydrophobicContact CG2-CG 4.32Å; I167-P367 HydrophobicContact CG2-CG 4.08Å
168	F	78.4	Confident	80	Confident	4 Å²	4	27.1 Å²	27.1	2%	0.018	15%	0.145	C	C	.	.	H	α-helix	trans	-60.8	-48.7	178.5	-90.9	-70	0	0	0	112.6	V85 A164 G165 A166 L171 A172 Y366 P367 M386	V85-F168 HydrophobicContact CG2-CD2 3.72Å; V85-F168 HydrophobicContact CG2-CE2 3.28Å; V85-F168 HydrophobicContact CG2-CZ 4.22Å; A164-F168 WeakPolarHBondContact O-CD2 3.18Å; A164-F168 PolarHBondContact O-N 3.08Å; G165-F168 WeakPolarHBondContact O-CB 3.32Å; G165-F168 PolarHBondContact O-N 3.27Å; A166-F168 VanDerWaalsContact C-N 3.33Å; A166-F168 PolarHBondContact O-N 3.22Å; F168-L171 PolarHBondContact O-N 3.49Å; F168-A172 WeakPolarHBondContact O-CB 3.35Å; F168-A172 PolarHBondContact O-N 3.23Å; F168-Y366 HydrophobicContact CZ-CD1 4.18Å; F168-P367 HydrophobicContact CD1-CB 4.09Å; F168-P367 HydrophobicContact CD1-CG 4.17Å; F168-P367 HydrophobicContact CE1-CB 3.59Å; F168-P367 HydrophobicContact CE1-CG 3.58Å; F168-P367 HydrophobicContact CE2-CG 4.02Å; F168-P367 HydrophobicContact CZ-CB 3.98Å; F168-P367 HydrophobicContact CZ-CG 3.43Å; F168-P367 VanDerWaalsContact CZ-CG 3.43Å; F168-M386 HydrophobicContact CD1-CE 4.41Å; F168-M386 HydrophobicContact CD1-SD 3.98Å; F168-M386 HydrophobicContact CD2-CE 4.27Å; F168-M386 HydrophobicContact CE1-CE 3.52Å; F168-M386 HydrophobicContact CE1-SD 3.26Å; F168-M386 WeakPolarHBondContact CE1-SD 3.44Å; F168-M386 HydrophobicContact CE2-CE 3.31Å; F168-M386 HydrophobicContact CE2-SD 4.13Å; F168-M386 HydrophobicContact CZ-CE 2.91Å; F168-M386 HydrophobicContact CZ-SD 3.41Å; F168-M386 WeakPolarHBondContact CZ-SD 3.19Å
169	I	79.4	Confident	79.7	Confident	11 Å²	11	31 Å²	31	6%	0.056	17%	0.165	C	C	.	.	H	α-helix	trans	-65.7	-40.6	-179.4	-64.8	165.5	0	0	0	111	G165 A166 A172 L173 L175 A180 L184 L387	G165-I169 WeakPolarHBondContact O-CG1 3.34Å; G165-I169 PolarHBondContact O-N 3.12Å; A166-I169 PolarHBondContact O-N 3.05Å; I169-A172 PolarHBondContact O-N 3.21Å; I169-L173 HydrophobicContact CG2-CB 4.37Å; I169-L173 HydrophobicContact CG2-CD1 4.15Å; I169-L173 HydrophobicContact CG2-CG 4.48Å; I169-L173 WeakPolarHBondContact O-CA 3.46Å; I169-L173 WeakPolarHBondContact O-CB 3.48Å; I169-L173 PolarHBondContact O-N 3.46Å; I169-L175 HydrophobicContact CG2-CB 4.15Å; I169-L175 HydrophobicContact CG2-CD1 3.78Å; I169-L175 HydrophobicContact CG2-CG 4.41Å; I169-A180 HydrophobicContact CB-CB 3.65Å; I169-A180 HydrophobicContact CD1-CB 3.96Å; I169-A180 HydrophobicContact CG1-CB 4.41Å; I169-A180 HydrophobicContact CG2-CB 3.3Å; I169-L184 HydrophobicContact CD1-CB 4.4Å; I169-L387 HydrophobicContact CD1-CD2 3.94Å; I169-L387 HydrophobicContact CG1-CD2 3.4Å; I169-L387 VanDerWaalsContact CG1-CD2 3.4Å
170	K	77.6	Confident	79.4	Confident	75 Å²	75	30.9 Å²	30.9	33%	0.326	16%	0.164	S	C	.	.	H	α-helix	trans	-61.4	-47	176.7	-177.9	-179.2	179.3	-174.3	0	111.1	A166 I167 G174 C355	A166-K170 WeakPolarHBondContact O-CB 3.17Å; A166-K170 PolarHBondContact O-N 3.14Å; I167-K170 PolarHBondContact O-N 3.22Å; K170-G174 WeakPolarHBondContact O-CA 2.98Å; K170-G174 PolarHBondContact O-N 3.38Å; K170-C355 PolarHBondContact NZ-O 3.25Å
171	L	76	Confident	79.1	Confident	19 Å²	19	31 Å²	31	10%	0.099	16%	0.164	C	C	.	.	H	α-helix	trans	-71	-36.4	179.8	-73.8	173.5	0	0	0	113.2	L19 I167 F168 Y364 P367 L371	L19-L171 WeakPolarHBondContact CB-O 3Å; I167-L171 HydrophobicContact CG2-CD1 3.76Å; I167-L171 HydrophobicContact CG2-CG 4.46Å; I167-L171 WeakPolarHBondContact O-CB 3.11Å; I167-L171 WeakPolarHBondContact O-CG 3.35Å; I167-L171 PolarHBondContact O-N 3.2Å; F168-L171 PolarHBondContact O-N 3.49Å; L171-Y364 HydrophobicContact CD1-CD1 3.47Å; L171-Y364 VanDerWaalsContact CD1-CD1 3.47Å; L171-Y364 HydrophobicContact CD1-CE1 3.77Å; L171-Y364 HydrophobicContact CD1-CG 4.04Å; L171-Y364 HydrophobicContact CD2-CD1 3.69Å; L171-Y364 HydrophobicContact CD2-CE1 3.61Å; L171-Y364 HydrophobicContact CG-CD1 3.93Å; L171-Y364 HydrophobicContact CG-CE1 3.77Å; L171-P367 HydrophobicContact CD1-CB 3.35Å; L171-P367 HydrophobicContact CD1-CG 3.92Å; L171-L371 HydrophobicContact CB-CD1 3.8Å
172	A	73.6	Confident	78.8	Confident	5 Å²	5	36.6 Å²	36.6	4%	0.041	19%	0.188	C	C	.	.	H	α-helix	trans	-84.5	-43.6	-176.4	0	0	0	0	0	112.9	S20 I23 F168 I169 L383	S20-A172 WeakPolarHBondContact CA-O 3.5Å; I23-A172 VanDerWaalsContact CD1-C 3.48Å; I23-A172 HydrophobicContact CD1-CB 3.63Å; I23-A172 WeakPolarHBondContact CD1-O 3.16Å; F168-A172 WeakPolarHBondContact O-CB 3.35Å; F168-A172 PolarHBondContact O-N 3.23Å; I169-A172 PolarHBondContact O-N 3.21Å; A172-L383 HydrophobicContact CB-CD1 4.18Å; A172-L383 HydrophobicContact CB-CD2 3.68Å
173	L	74.1	Confident	78.4	Confident	86 Å²	86	40 Å²	40	45%	0.45	21%	0.206	S	C	.	.	H	α-helix	trans	-107	-6.3	-172.6	-57.2	-174.7	0	0	0	112.9	I169 L175	I169-L173 HydrophobicContact CG2-CB 4.37Å; I169-L173 HydrophobicContact CG2-CD1 4.15Å; I169-L173 HydrophobicContact CG2-CG 4.48Å; I169-L173 WeakPolarHBondContact O-CA 3.46Å; I169-L173 WeakPolarHBondContact O-CB 3.48Å; I169-L173 PolarHBondContact O-N 3.46Å; L173-L175 HydrophobicContact CB-CD1 3.85Å; L173-L175 HydrophobicContact CB-CG 3.73Å; L173-L175 HydrophobicContact CD1-CD1 3.9Å; L173-L175 PolarHBondContact O-N 3.41Å
174	G	74.2	Confident	78.3	Confident	49 Å²	49	39 Å²	39	51%	0.505	20%	0.202	S	C	.	.			trans	66.3	16.1	-176.7	0	0	0	0	0	113.3	K170	K170-G174 WeakPolarHBondContact O-CA 2.98Å; K170-G174 PolarHBondContact O-N 3.38Å
175	L	75	Confident	78	Confident	52 Å²	52	39.1 Å²	39.1	27%	0.272	20%	0.202	S	C	.	.			trans	-78.6	150.7	-177.1	-63.8	175.1	0	0	0	111.3	I169 L173 L179 I183	I169-L175 HydrophobicContact CG2-CB 4.15Å; I169-L175 HydrophobicContact CG2-CD1 3.78Å; I169-L175 HydrophobicContact CG2-CG 4.41Å; L173-L175 HydrophobicContact CB-CD1 3.85Å; L173-L175 HydrophobicContact CB-CG 3.73Å; L173-L175 HydrophobicContact CD1-CD1 3.9Å; L173-L175 PolarHBondContact O-N 3.41Å; L175-L179 HydrophobicContact CD2-CD2 4.15Å; L175-I183 HydrophobicContact CD1-CD1 4.34Å
176	D	80.3	Confident	77.6	Confident	102 Å²	102	41.2 Å²	41.2	55%	0.545	22%	0.22	S	C	.	.			trans	-58.6	144.1	167.1	176.5	-134.2	0	0	0	110.9	Y178 L179 A180	D176-Y178 VanDerWaalsContact C-N 3.34Å; D176-Y178 PolarHBondContact O-N 2.9Å; D176-L179 HydrophobicContact CB-CB 4.31Å; D176-L179 PolarHBondContact O-N 3.17Å; D176-A180 WeakPolarHBondContact O-CB 3.29Å; D176-A180 PolarHBondContact O-N 2.96Å
177	L	73.9	Confident	77.4	Confident	16 Å²	16	45.3 Å²	45.3	8%	0.084	24%	0.24	C	C	.	.	H	α-helix	trans	-57.6	-45	-175.6	-168.7	85.6	0	0	0	111.6	A166 A180 I181	A166-L177 HydrophobicContact CB-CD1 3.32Å; A166-L177 HydrophobicContact CB-CG 3.92Å; L177-A180 WeakPolarHBondContact O-CB 3.42Å; L177-A180 PolarHBondContact O-N 3.01Å; L177-I181 HydrophobicContact CD2-CD1 4.47Å; L177-I181 HydrophobicContact CG-CD1 4.13Å; L177-I181 WeakPolarHBondContact O-CB 3.33Å; L177-I181 VanDerWaalsContact O-CG1 3.26Å; L177-I181 WeakPolarHBondContact O-CG1 3.4Å; L177-I181 PolarHBondContact O-N 3.25Å
178	Y	80.1	Confident	77.4	Confident	104 Å²	104	45.2 Å²	45.2	41%	0.408	24%	0.239	S	C	.	.	H	α-helix	trans	-70.4	-37.8	-178.1	-72.4	-80.8	0	0	0	112	D176 I181 F182	D176-Y178 VanDerWaalsContact C-N 3.34Å; D176-Y178 PolarHBondContact O-N 2.9Å; Y178-I181 PolarHBondContact O-N 3.09Å; Y178-F182 WeakPolarHBondContact O-CB 3.49Å; Y178-F182 PolarHBondContact O-N 3.4Å
179	L	79.1	Confident	77.2	Confident	83 Å²	83	45.4 Å²	45.4	44%	0.435	24%	0.242	S	C	.	.	H	α-helix	trans	-64.6	-43.9	174.3	-178.9	61.4	0	0	0	111.3	L175 D176 I181 F182 I183	L175-L179 HydrophobicContact CD2-CD2 4.15Å; D176-L179 HydrophobicContact CB-CB 4.31Å; D176-L179 PolarHBondContact O-N 3.17Å; L179-I181 VanDerWaalsContact C-N 3.35Å; L179-I181 PolarHBondContact O-N 3.37Å; L179-F182 PolarHBondContact O-N 2.85Å; L179-I183 HydrophobicContact CD1-CD1 4.18Å; L179-I183 HydrophobicContact CD1-CG1 4.43Å; L179-I183 HydrophobicContact CG-CD1 4.08Å; L179-I183 WeakPolarHBondContact O-CG1 3.15Å; L179-I183 PolarHBondContact O-N 3.08Å
180	A	77.8	Confident	77	Confident	0 Å²	0	49.2 Å²	49.2	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-57.7	-47.5	175.6	0	0	0	0	0	112	I169 D176 L177 F182 I183 L184	I169-A180 HydrophobicContact CB-CB 3.65Å; I169-A180 HydrophobicContact CD1-CB 3.96Å; I169-A180 HydrophobicContact CG1-CB 4.41Å; I169-A180 HydrophobicContact CG2-CB 3.3Å; D176-A180 WeakPolarHBondContact O-CB 3.29Å; D176-A180 PolarHBondContact O-N 2.96Å; L177-A180 WeakPolarHBondContact O-CB 3.42Å; L177-A180 PolarHBondContact O-N 3.01Å; A180-F182 PolarHBondContact O-N 2.73Å; A180-I183 PolarHBondContact O-N 3.08Å; A180-L184 WeakPolarHBondContact O-CB 3.32Å; A180-L184 PolarHBondContact O-N 3.25Å
181	I	79.1	Confident	76.7	Confident	3 Å²	3	47.8 Å²	47.8	2%	0.015	26%	0.258	C	S	.	.	H	α-helix	trans	-59.9	-45.5	176.4	-76.1	169.6	0	0	0	111.3	M162 A166 L177 Y178 L179 L184 L185 I438 V441	M162-I181 HydrophobicContact CE-CB 4.43Å; M162-I181 HydrophobicContact CE-CG1 4.46Å; M162-I181 HydrophobicContact CE-CG2 3.27Å; A166-I181 HydrophobicContact CB-CD1 4.06Å; A166-I181 HydrophobicContact CB-CG1 3.75Å; L177-I181 HydrophobicContact CD2-CD1 4.47Å; L177-I181 HydrophobicContact CG-CD1 4.13Å; L177-I181 WeakPolarHBondContact O-CB 3.33Å; L177-I181 VanDerWaalsContact O-CG1 3.26Å; L177-I181 WeakPolarHBondContact O-CG1 3.4Å; L177-I181 PolarHBondContact O-N 3.25Å; Y178-I181 PolarHBondContact O-N 3.09Å; L179-I181 VanDerWaalsContact C-N 3.35Å; L179-I181 PolarHBondContact O-N 3.37Å; I181-L184 PolarHBondContact O-N 3.15Å; I181-L185 HydrophobicContact CG2-CD1 3.87Å; I181-L185 HydrophobicContact CG2-CG 4.43Å; I181-L185 WeakPolarHBondContact O-CB 3.45Å; I181-L185 WeakPolarHBondContact O-CG 3.49Å; I181-L185 PolarHBondContact O-N 3.39Å; I181-I438 HydrophobicContact CG2-CG1 4.2Å; I181-V441 HydrophobicContact CD1-CG1 3.9Å; I181-V441 HydrophobicContact CD1-CG2 4.01Å
182	F	80.1	Confident	76.5	Confident	131 Å²	131	47.2 Å²	47.2	58%	0.575	26%	0.256	S	S	*	.	H	α-helix	trans	-62.3	-47.8	-179.5	178.3	-96.3	0	0	0	112.2	Y178 L179 A180 L184 L185 A186	Y178-F182 WeakPolarHBondContact O-CB 3.49Å; Y178-F182 PolarHBondContact O-N 3.4Å; L179-F182 PolarHBondContact O-N 2.85Å; A180-F182 PolarHBondContact O-N 2.73Å; F182-L184 VanDerWaalsContact C-N 3.31Å; F182-L184 PolarHBondContact O-N 3.17Å; F182-L185 PolarHBondContact O-N 3.38Å; F182-A186 WeakPolarHBondContact O-CB 3.35Å; F182-A186 PolarHBondContact O-N 3.39Å
183	I	77.1	Confident	76.3	Confident	72 Å²	72	48.9 Å²	48.9	37%	0.369	26%	0.263	S	S	.	.	H	α-helix	trans	-59.3	-46	178	-68.1	168.1	0	0	0	110.2	L175 L179 A180 L185 A186 M187	L175-I183 HydrophobicContact CD1-CD1 4.34Å; L179-I183 HydrophobicContact CD1-CD1 4.18Å; L179-I183 HydrophobicContact CD1-CG1 4.43Å; L179-I183 HydrophobicContact CG-CD1 4.08Å; L179-I183 WeakPolarHBondContact O-CG1 3.15Å; L179-I183 PolarHBondContact O-N 3.08Å; A180-I183 PolarHBondContact O-N 3.08Å; I183-L185 PolarHBondContact O-N 3.09Å; I183-A186 PolarHBondContact O-N 3.45Å; I183-M187 HydrophobicContact CG2-SD 4.06Å; I183-M187 WeakPolarHBondContact O-CG 3.34Å; I183-M187 PolarHBondContact O-N 2.95Å
184	L	77.9	Confident	75.9	Confident	6 Å²	6	45.4 Å²	45.4	3%	0.031	25%	0.246	C	C	.	.	H	α-helix	trans	-59.3	-48.1	179.5	176.9	69	0	0	0	112.5	I169 A180 I181 F182 M187 T188 L390 I391 L394	I169-L184 HydrophobicContact CD1-CB 4.4Å; A180-L184 WeakPolarHBondContact O-CB 3.32Å; A180-L184 PolarHBondContact O-N 3.25Å; I181-L184 PolarHBondContact O-N 3.15Å; F182-L184 VanDerWaalsContact C-N 3.31Å; F182-L184 PolarHBondContact O-N 3.17Å; L184-M187 PolarHBondContact O-N 3.2Å; L184-T188 WeakPolarHBondContact O-CB 3.48Å; L184-T188 PolarHBondContact O-N 3.41Å; L184-T188 PolarHBondContact O-OG1 3.34Å; L184-L390 HydrophobicContact CD1-CB 4.5Å; L184-L390 HydrophobicContact CD1-CD2 3.31Å; L184-L390 HydrophobicContact CD1-CG 3.62Å; L184-L390 HydrophobicContact CD2-CD1 3.93Å; L184-L390 HydrophobicContact CD2-CD2 3.37Å; L184-L390 HydrophobicContact CD2-CG 3.64Å; L184-L390 HydrophobicContact CG-CD2 3.89Å; L184-L390 HydrophobicContact CG-CG 4.14Å; L184-I391 HydrophobicContact CD1-CG1 3.82Å; L184-L394 HydrophobicContact CD1-CD1 4.5Å; L184-L394 HydrophobicContact CD2-CD1 3.65Å; L184-L394 HydrophobicContact CG-CD1 3.92Å
185	L	78.9	Confident	75.5	Confident	2 Å²	2	43.2 Å²	43.2	1%	0.01	22%	0.223	C	C	.	.	H	α-helix	trans	-67	-38.7	-179.3	-76.3	178.5	0	0	0	111.7	M162 I181 F182 I183 T188 A189 L394 F398 T434 I438	M162-L185 HydrophobicContact CE-CD1 3.55Å; M162-L185 HydrophobicContact CE-CD2 4.34Å; M162-L185 HydrophobicContact CE-CG 4.15Å; M162-L185 HydrophobicContact CG-CD2 4.4Å; M162-L185 HydrophobicContact SD-CD1 4.26Å; M162-L185 HydrophobicContact SD-CD2 4.07Å; I181-L185 HydrophobicContact CG2-CD1 3.87Å; I181-L185 HydrophobicContact CG2-CG 4.43Å; I181-L185 WeakPolarHBondContact O-CB 3.45Å; I181-L185 WeakPolarHBondContact O-CG 3.49Å; I181-L185 PolarHBondContact O-N 3.39Å; F182-L185 PolarHBondContact O-N 3.38Å; I183-L185 PolarHBondContact O-N 3.09Å; L185-T188 PolarHBondContact O-N 3.45Å; L185-A189 VanDerWaalsContact O-CB 3.24Å; L185-A189 WeakPolarHBondContact O-CB 3.26Å; L185-A189 PolarHBondContact O-N 3.46Å; L185-L394 HydrophobicContact CD2-CD1 4.49Å; L185-F398 HydrophobicContact CD2-CE2 4.17Å; L185-F398 HydrophobicContact CD2-CZ 3.82Å; L185-T434 HydrophobicContact CB-CG2 3.69Å; L185-T434 HydrophobicContact CD1-CG2 3.75Å; L185-T434 HydrophobicContact CD2-CG2 4.12Å; L185-T434 HydrophobicContact CG-CG2 4.07Å; L185-I438 HydrophobicContact CD1-CD1 3.58Å; L185-I438 HydrophobicContact CD1-CG1 3.26Å
186	A	77.1	Confident	75.4	Confident	44 Å²	44	41 Å²	41	36%	0.364	21%	0.212	S	C	.	.	H	α-helix	trans	-61.6	-47.2	174.4	0	0	0	0	0	111.6	F182 I183 A189 V190	F182-A186 WeakPolarHBondContact O-CB 3.35Å; F182-A186 PolarHBondContact O-N 3.39Å; I183-A186 PolarHBondContact O-N 3.45Å; A186-A189 PolarHBondContact O-N 3.46Å; A186-V190 WeakPolarHBondContact O-CG2 3.38Å; A186-V190 PolarHBondContact O-N 2.71Å; A186-V190 VanDerWaalsContact O-N 3.1Å
187	M	76.8	Confident	75.1	Confident	85 Å²	85	36.1 Å²	36.1	42%	0.419	19%	0.187	S	C	.	.	H	α-helix	trans	-61.5	-46.6	176.6	-71.7	179.3	68.1	0	0	111.8	F36 I183 L184 A189 V190 Y191 I391	F36-M187 HydrophobicContact CE1-CE 4.15Å; I183-M187 HydrophobicContact CG2-SD 4.06Å; I183-M187 WeakPolarHBondContact O-CG 3.34Å; I183-M187 PolarHBondContact O-N 2.95Å; L184-M187 PolarHBondContact O-N 3.2Å; M187-A189 PolarHBondContact O-N 3.49Å; M187-V190 PolarHBondContact O-N 2.85Å; M187-Y191 PolarHBondContact O-N 3.17Å; M187-I391 HydrophobicContact CB-CD1 4.49Å; M187-I391 HydrophobicContact CE-CD1 3.84Å
188	T	78.8	Confident	75.3	Confident	0 Å²	0	35.7 Å²	35.7	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-61.2	-44.3	178.1	-56.7	0	0	0	0	111.5	L184 L185 V190 Y191 T192 L394 F398	L184-T188 WeakPolarHBondContact O-CB 3.48Å; L184-T188 PolarHBondContact O-N 3.41Å; L184-T188 PolarHBondContact O-OG1 3.34Å; L185-T188 PolarHBondContact O-N 3.45Å; T188-V190 PolarHBondContact O-N 3.44Å; T188-Y191 PolarHBondContact O-N 3.22Å; T188-T192 WeakPolarHBondContact O-CB 3.31Å; T188-T192 PolarHBondContact O-N 2.83Å; T188-T192 PolarHBondContact O-OG1 3.48Å; T188-L394 HydrophobicContact CG2-CB 3.53Å; T188-F398 HydrophobicContact CG2-CD2 3.67Å; T188-F398 HydrophobicContact CG2-CE2 3.71Å
189	A	74.8	Confident	75.3	Confident	8 Å²	8	30.9 Å²	30.9	7%	0.066	17%	0.167	C	C	.	.	H	α-helix	trans	-61.8	-45.1	179.4	0	0	0	0	0	111.5	L185 A186 M187 Y191 T192 I193 L431	L185-A189 VanDerWaalsContact O-CB 3.24Å; L185-A189 WeakPolarHBondContact O-CB 3.26Å; L185-A189 PolarHBondContact O-N 3.46Å; A186-A189 PolarHBondContact O-N 3.46Å; M187-A189 PolarHBondContact O-N 3.49Å; A189-Y191 VanDerWaalsContact C-N 3.34Å; A189-Y191 PolarHBondContact O-N 3.22Å; A189-T192 PolarHBondContact O-N 3.45Å; A189-I193 WeakPolarHBondContact O-CB 3.32Å; A189-I193 WeakPolarHBondContact O-CD1 3.37Å; A189-I193 WeakPolarHBondContact O-CG1 3.43Å; A189-I193 PolarHBondContact O-N 2.84Å; A189-L431 HydrophobicContact CB-CD2 4.43Å
190	V	74	Confident	75.4	Confident	92 Å²	92	27.1 Å²	27.1	56%	0.558	15%	0.147	S	C	*	.	H	α-helix	trans	-59.8	-45.7	175.9	172.4	0	0	0	0	110.9	A186 M187 T188 T194	A186-V190 WeakPolarHBondContact O-CG2 3.38Å; A186-V190 PolarHBondContact O-N 2.71Å; A186-V190 VanDerWaalsContact O-N 3.1Å; M187-V190 PolarHBondContact O-N 2.85Å; T188-V190 PolarHBondContact O-N 3.44Å; V190-T194 WeakPolarHBondContact O-CB 3.46Å; V190-T194 VanDerWaalsContact O-CG2 3.25Å; V190-T194 WeakPolarHBondContact O-CG2 3.38Å; V190-T194 PolarHBondContact O-N 2.89Å; V190-T194 PolarHBondContact O-OG1 2.88Å
191	Y	71.8	Confident	75.9	Confident	44 Å²	44	27.2 Å²	27.2	17%	0.173	15%	0.148	C	C	.	.	H	α-helix	trans	-66.1	-41.1	-179.7	-165	-98.8	0	0	0	112.4	M187 T188 A189 T194 G195 T203 T395	M187-Y191 PolarHBondContact O-N 3.17Å; T188-Y191 PolarHBondContact O-N 3.22Å; A189-Y191 VanDerWaalsContact C-N 3.34Å; A189-Y191 PolarHBondContact O-N 3.22Å; Y191-T194 PolarHBondContact O-OG1 3.01Å; Y191-G195 WeakPolarHBondContact O-CA 3.22Å; Y191-G195 PolarHBondContact O-N 3.34Å; Y191-T203 WeakPolarHBondContact OH-CB 3.12Å; Y191-T203 WeakPolarHBondContact OH-CG2 3.42Å; Y191-T203 PolarHBondContact OH-OG1 3.13Å; Y191-T395 HydrophobicContact CD1-CG2 3.89Å; Y191-T395 HydrophobicContact CE1-CG2 4.34Å
192	T	72.5	Confident	76.2	Confident	8 Å²	8	30.1 Å²	30.1	5%	0.049	16%	0.159	C	C	.	.	H	α-helix	trans	-69.2	-40.4	179.2	-52.7	0	0	0	0	112.4	T188 A189 T194 G195 T395 F398 V430	T188-T192 WeakPolarHBondContact O-CB 3.31Å; T188-T192 PolarHBondContact O-N 2.83Å; T188-T192 PolarHBondContact O-OG1 3.48Å; A189-T192 PolarHBondContact O-N 3.45Å; T192-T194 VanDerWaalsContact C-N 3.28Å; T192-T194 PolarHBondContact O-N 3.42Å; T192-G195 VanDerWaalsContact O-O 3.08Å; T192-T395 HydrophobicContact CG2-CG2 4.41Å; T192-T395 WeakPolarHBondContact OG1-CA 3.22Å; T192-F398 HydrophobicContact CG2-CB 3.91Å; T192-V430 HydrophobicContact CG2-CG1 4.49Å; T192-V430 HydrophobicContact CG2-CG2 4.45Å
193	I	68.8	Low	76.5	Confident	39 Å²	39	24.1 Å²	24.1	20%	0.2	13%	0.133	C	C	.	.	H	α-helix	trans	-67.4	-35	-179.2	-71.4	166.2	0	0	0	110.8	A189 R427 L431	A189-I193 WeakPolarHBondContact O-CB 3.32Å; A189-I193 WeakPolarHBondContact O-CD1 3.37Å; A189-I193 WeakPolarHBondContact O-CG1 3.43Å; A189-I193 PolarHBondContact O-N 2.84Å; I193-R427 HydrophobicContact CG1-CG 4.45Å; I193-R427 HydrophobicContact CG2-CG 4.44Å; I193-R427 PolarHBondContact O-NE 3.21Å; I193-R427 PolarHBondContact O-NH2 3.48Å; I193-L431 HydrophobicContact CD1-CD2 4.18Å
194	T	66.1	Low	77.1	Confident	14 Å²	14	20.7 Å²	20.7	9%	0.086	12%	0.116	C	C	.	.	H	α-helix	trans	-88.5	-37.5	-175.8	57.2	0	0	0	0	112.8	M47 R52 V190 Y191 T192 F606	M47-T194 WeakPolarHBondContact CE-O 3.43Å; R52-T194 PolarHBondContact NH1-O 2.68Å; V190-T194 WeakPolarHBondContact O-CB 3.46Å; V190-T194 VanDerWaalsContact O-CG2 3.25Å; V190-T194 WeakPolarHBondContact O-CG2 3.38Å; V190-T194 PolarHBondContact O-N 2.89Å; V190-T194 PolarHBondContact O-OG1 2.88Å; Y191-T194 PolarHBondContact O-OG1 3.01Å; T192-T194 VanDerWaalsContact C-N 3.28Å; T192-T194 PolarHBondContact O-N 3.42Å; T194-F606 HydrophobicContact CG2-CD1 4.07Å; T194-F606 HydrophobicContact CG2-CD2 4.37Å; T194-F606 HydrophobicContact CG2-CE1 3.39Å; T194-F606 HydrophobicContact CG2-CE2 3.74Å; T194-F606 HydrophobicContact CG2-CZ 3.21Å
195	G	65.4	Low	77.7	Confident	3 Å²	3	20.7 Å²	20.7	3%	0.031	12%	0.116	C	C	.	.			trans	-84	143.5	-179.7	0	0	0	0	0	113.6	F58 Y191 T192	F58-G195 WeakPolarHBondContact CE2-O 3.49Å; Y191-G195 WeakPolarHBondContact O-CA 3.22Å; Y191-G195 PolarHBondContact O-N 3.34Å; T192-G195 VanDerWaalsContact O-O 3.08Å
196	G	72.4	Confident	78.2	Confident	4 Å²	4	22.5 Å²	22.5	4%	0.041	13%	0.125	C	C	.	.			trans	-100.2	176.3	163.5	0	0	0	0	0	111	A198 S199 V200	G196-A198 PolarHBondContact O-N 3.18Å; G196-S199 WeakPolarHBondContact O-CB 3.39Å; G196-S199 PolarHBondContact O-N 3.2Å; G196-V200 PolarHBondContact O-N 3.27Å
197	L	75.6	Confident	78.9	Confident	1 Å²	1	20.7 Å²	20.7	1%	0.005	11%	0.109	C	C	.	.	H	α-helix	trans	-52.7	-36.4	-176.4	-178.3	65.9	0	0	0	113.2	F58 F59 S199 V200 I201 Q299 R300	F58-L197 WeakPolarHBondContact O-CB 3.41Å; F58-L197 PolarHBondContact O-N 3.19Å; F59-L197 WeakPolarHBondContact O-CD2 3.18Å; L197-S199 PolarHBondContact O-N 3.42Å; L197-V200 WeakPolarHBondContact O-CB 3.41Å; L197-V200 PolarHBondContact O-N 2.94Å; L197-I201 HydrophobicContact CD1-CD1 4.39Å; L197-I201 HydrophobicContact CD1-CG1 4.41Å; L197-I201 HydrophobicContact CD2-CD1 4.36Å; L197-I201 HydrophobicContact CG-CD1 3.94Å; L197-I201 HydrophobicContact CG-CG1 4.38Å; L197-I201 WeakPolarHBondContact O-CG1 3.39Å; L197-I201 PolarHBondContact O-N 3.41Å; L197-Q299 HydrophobicContact CD2-CG 4.11Å; L197-R300 HydrophobicContact CD1-CG 4.49Å
198	A	78.1	Confident	79.6	Confident	7 Å²	7	16.9 Å²	16.9	6%	0.058	9%	0.091	C	C	.	.	H	α-helix	trans	-60.6	-44.3	176.8	0	0	0	0	0	112.7	T50 A61 G196 V200 I201 Y202	T50-A198 HydrophobicContact CG2-CB 3.8Å; A61-A198 HydrophobicContact CB-CB 3.71Å; G196-A198 PolarHBondContact O-N 3.18Å; A198-V200 VanDerWaalsContact C-N 3.31Å; A198-V200 PolarHBondContact O-N 3.14Å; A198-I201 PolarHBondContact O-N 2.89Å; A198-Y202 WeakPolarHBondContact O-CD2 3.4Å; A198-Y202 PolarHBondContact O-N 3.29Å; A198-Y202 VanDerWaalsContact O-N 3.14Å
199	S	79.8	Confident	80.3	Confident	3 Å²	3	21 Å²	21	2%	0.021	11%	0.112	C	C	.	.	H	α-helix	trans	-61.3	-44.2	178.5	-171.8	0	0	0	0	110.4	G43 G196 L197 Y202 T203	G43-S199 PolarHBondContact O-OG 3.22Å; G43-S199 VanDerWaalsContact O-OG 3.12Å; G196-S199 WeakPolarHBondContact O-CB 3.39Å; G196-S199 PolarHBondContact O-N 3.2Å; L197-S199 PolarHBondContact O-N 3.42Å; S199-Y202 PolarHBondContact O-N 3.31Å; S199-T203 PolarHBondContact O-N 2.83Å; S199-T203 PolarHBondContact O-OG1 3.24Å
200	V	81.3	Confident	81.1	Confident	4 Å²	4	22.2 Å²	22.2	2%	0.024	12%	0.117	C	C	.	.	H	α-helix	trans	-57.5	-52	175.5	-177.1	0	0	0	0	110.9	G196 L197 A198 Y202 T203 D204 T395	G196-V200 PolarHBondContact O-N 3.27Å; L197-V200 WeakPolarHBondContact O-CB 3.41Å; L197-V200 PolarHBondContact O-N 2.94Å; A198-V200 VanDerWaalsContact C-N 3.31Å; A198-V200 PolarHBondContact O-N 3.14Å; V200-Y202 VanDerWaalsContact C-N 3.33Å; V200-Y202 PolarHBondContact O-N 2.9Å; V200-T203 PolarHBondContact O-N 3.37Å; V200-T203 PolarHBondContact O-OG1 2.93Å; V200-T203 VanDerWaalsContact O-OG1 3.07Å; V200-D204 WeakPolarHBondContact O-CB 3.25Å; V200-D204 PolarHBondContact O-N 2.95Å; V200-T395 HydrophobicContact CG2-CG2 3.65Å
201	I	86.8	Confident	82	Confident	1 Å²	1	17.9 Å²	17.9	1%	0.005	9%	0.091	C	C	.	.	H	α-helix	trans	-57.5	-44.2	-178.6	-69.9	169.2	0	0	0	112.1	V65 P69 L197 A198 T205	V65-I201 HydrophobicContact CG1-CD1 4.39Å; V65-I201 HydrophobicContact CG1-CG2 3.96Å; V65-I201 HydrophobicContact CG2-CD1 4.06Å; P69-I201 HydrophobicContact CB-CG2 3.83Å; L197-I201 HydrophobicContact CD1-CD1 4.39Å; L197-I201 HydrophobicContact CD1-CG1 4.41Å; L197-I201 HydrophobicContact CD2-CD1 4.36Å; L197-I201 HydrophobicContact CG-CD1 3.94Å; L197-I201 HydrophobicContact CG-CG1 4.38Å; L197-I201 WeakPolarHBondContact O-CG1 3.39Å; L197-I201 PolarHBondContact O-N 3.41Å; A198-I201 PolarHBondContact O-N 2.89Å; I201-T205 WeakPolarHBondContact O-CB 3.42Å; I201-T205 PolarHBondContact O-N 3.23Å; I201-T205 PolarHBondContact O-OG1 3.48Å
202	Y	86.6	Confident	83.1	Confident	64 Å²	64	17 Å²	17	25%	0.251	9%	0.088	S	C	.	.	H	α-helix	trans	-70.9	-38.8	-178.4	-75.1	-66	0	0	0	112.8	A46 P69 A198 S199 V200 T205 L206	A46-Y202 HydrophobicContact CB-CD2 3.8Å; A46-Y202 HydrophobicContact CB-CG 4.37Å; P69-Y202 HydrophobicContact CB-CE1 4.48Å; P69-Y202 HydrophobicContact CG-CE1 4.38Å; A198-Y202 WeakPolarHBondContact O-CD2 3.4Å; A198-Y202 PolarHBondContact O-N 3.29Å; A198-Y202 VanDerWaalsContact O-N 3.14Å; S199-Y202 PolarHBondContact O-N 3.31Å; V200-Y202 VanDerWaalsContact C-N 3.33Å; V200-Y202 PolarHBondContact O-N 2.9Å; Y202-T205 WeakPolarHBondContact O-CB 3.38Å; Y202-T205 PolarHBondContact O-N 2.92Å; Y202-L206 PolarHBondContact O-N 2.8Å
203	T	86.1	Confident	84.2	Confident	6 Å²	6	21 Å²	21	4%	0.037	11%	0.109	C	C	.	.	H	α-helix	trans	-69.6	-38.1	174.9	50	0	0	0	0	112.6	V39 V42 Y191 S199 V200 T205 L206 Q207	V39-T203 HydrophobicContact CG1-CG2 4.14Å; V42-T203 HydrophobicContact CB-CG2 4.46Å; V42-T203 HydrophobicContact CG1-CG2 4.16Å; Y191-T203 WeakPolarHBondContact OH-CB 3.12Å; Y191-T203 WeakPolarHBondContact OH-CG2 3.42Å; Y191-T203 PolarHBondContact OH-OG1 3.13Å; S199-T203 PolarHBondContact O-N 2.83Å; S199-T203 PolarHBondContact O-OG1 3.24Å; V200-T203 PolarHBondContact O-N 3.37Å; V200-T203 PolarHBondContact O-OG1 2.93Å; V200-T203 VanDerWaalsContact O-OG1 3.07Å; T203-T205 PolarHBondContact O-N 3.5Å; T203-L206 PolarHBondContact O-N 2.88Å; T203-Q207 WeakPolarHBondContact O-CB 3.13Å; T203-Q207 PolarHBondContact O-N 3.05Å
204	D	89.6	Confident	85.3	Confident	0 Å²	0	19.2 Å²	19.2	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-58.6	-38	173.1	-67.7	-2.8	0	0	0	111.2	S73 A76 V200 Q207 T208 R300 S392	S73-D204 PolarHBondContact OG-OD2 2.86Å; A76-D204 HydrophobicContact CB-CB 3.9Å; V200-D204 WeakPolarHBondContact O-CB 3.25Å; V200-D204 PolarHBondContact O-N 2.95Å; D204-Q207 PolarHBondContact O-N 3.47Å; D204-T208 WeakPolarHBondContact O-CB 3.45Å; D204-T208 PolarHBondContact O-N 2.86Å; D204-T208 PolarHBondContact O-OG1 3.34Å; D204-R300 IonicContact OD2-NH2 3.52Å; D204-R300 PolarHBondContact OD2-NH2 3.32Å; D204-S392 WeakPolarHBondContact OD1-CB 3.44Å; D204-S392 PolarHBondContact OD1-OG 3.29Å
205	T	90.8	Very high	86.7	Confident	5 Å²	5	18.6 Å²	18.6	3%	0.031	10%	0.096	C	C	.	.	H	α-helix	trans	-66.2	-48.8	-179.7	-57.7	0	0	0	0	111.5	W68 P69 A72 I201 Y202 T203 Q207 T208 I209	W68-T205 HydrophobicContact CE3-CG2 3.73Å; W68-T205 HydrophobicContact CH2-CG2 4.39Å; W68-T205 HydrophobicContact CZ3-CG2 3.36Å; P69-T205 WeakPolarHBondContact CA-OG1 3.41Å; P69-T205 HydrophobicContact CB-CG2 4.3Å; P69-T205 WeakPolarHBondContact CB-OG1 3.47Å; P69-T205 PolarHBondContact O-OG1 3.3Å; A72-T205 HydrophobicContact CB-CG2 3.97Å; I201-T205 WeakPolarHBondContact O-CB 3.42Å; I201-T205 PolarHBondContact O-N 3.23Å; I201-T205 PolarHBondContact O-OG1 3.48Å; Y202-T205 WeakPolarHBondContact O-CB 3.38Å; Y202-T205 PolarHBondContact O-N 2.92Å; T203-T205 PolarHBondContact O-N 3.5Å; T205-Q207 VanDerWaalsContact C-N 3.33Å; T205-Q207 PolarHBondContact O-N 3.34Å; T205-T208 PolarHBondContact O-N 3.3Å; T205-I209 WeakPolarHBondContact O-CG1 3.41Å; T205-I209 PolarHBondContact O-N 3.06Å
206	L	89.6	Confident	88.2	Confident	41 Å²	41	22.8 Å²	22.8	22%	0.215	11%	0.114	C	C	.	.	H	α-helix	trans	-58.9	-48.5	175.3	176.1	66.8	0	0	0	110.7	V38 V39 V42 Y202 T203 T208 I209 I210	V38-L206 HydrophobicContact CG1-CD2 3.83Å; V39-L206 HydrophobicContact CG2-CD2 4.18Å; V42-L206 HydrophobicContact CG2-CD2 4.12Å; Y202-L206 PolarHBondContact O-N 2.8Å; T203-L206 PolarHBondContact O-N 2.88Å; L206-T208 VanDerWaalsContact C-N 3.35Å; L206-T208 PolarHBondContact O-N 3.35Å; L206-I209 PolarHBondContact O-N 2.89Å; L206-I210 HydrophobicContact CD1-CD1 3.87Å; L206-I210 HydrophobicContact CD1-CG1 4.39Å; L206-I210 HydrophobicContact CG-CD1 3.88Å; L206-I210 WeakPolarHBondContact O-CG1 3.45Å; L206-I210 PolarHBondContact O-N 3.01Å
207	Q	90.4	Very high	89.3	Confident	6 Å²	6	25.2 Å²	25.2	3%	0.028	13%	0.125	C	C	.	.	H	α-helix	trans	-59.3	-45.3	179.7	-179.6	-165.1	-65.5	0	0	111.7	T203 D204 T205 I209 I210 M211 A388	T203-Q207 WeakPolarHBondContact O-CB 3.13Å; T203-Q207 PolarHBondContact O-N 3.05Å; D204-Q207 PolarHBondContact O-N 3.47Å; T205-Q207 VanDerWaalsContact C-N 3.33Å; T205-Q207 PolarHBondContact O-N 3.34Å; Q207-I209 VanDerWaalsContact C-N 3.29Å; Q207-I209 PolarHBondContact O-N 2.77Å; Q207-I210 PolarHBondContact O-N 3.47Å; Q207-M211 WeakPolarHBondContact O-CB 3.31Å; Q207-M211 PolarHBondContact O-N 2.91Å; Q207-A388 PolarHBondContact OE1-O 3.47Å
208	T	92.8	Very high	90.3	Very high	4 Å²	4	25.1 Å²	25.1	3%	0.025	13%	0.125	C	C	.	.	H	α-helix	trans	-55.5	-45.7	178.2	-62.1	0	0	0	0	111.3	A72 F75 A76 D204 T205 L206 M211 L212 L320	A72-T208 HydrophobicContact CB-CG2 4.2Å; A72-T208 PolarHBondContact O-OG1 2.9Å; F75-T208 HydrophobicContact CD1-CG2 3.59Å; F75-T208 HydrophobicContact CE1-CG2 4.04Å; A76-T208 WeakPolarHBondContact CB-OG1 3.44Å; D204-T208 WeakPolarHBondContact O-CB 3.45Å; D204-T208 PolarHBondContact O-N 2.86Å; D204-T208 PolarHBondContact O-OG1 3.34Å; T205-T208 PolarHBondContact O-N 3.3Å; L206-T208 VanDerWaalsContact C-N 3.35Å; L206-T208 PolarHBondContact O-N 3.35Å; T208-M211 PolarHBondContact O-N 3.41Å; T208-L212 HydrophobicContact CG2-CD1 3.89Å; T208-L212 HydrophobicContact CG2-CG 4.34Å; T208-L212 WeakPolarHBondContact O-CB 3.42Å; T208-L212 VanDerWaalsContact O-CG 3.23Å; T208-L212 WeakPolarHBondContact O-CG 3.42Å; T208-L212 PolarHBondContact O-N 3.12Å; T208-L320 HydrophobicContact CG2-CD1 4.37Å
209	I	93.4	Very high	91.2	Very high	87 Å²	87	26.8 Å²	26.8	45%	0.446	13%	0.132	S	C	.	.	H	α-helix	trans	-62	-50.3	-179.6	-66.9	167.2	0	0	0	110.4	T205 L206 Q207 M211 L212 I213	T205-I209 WeakPolarHBondContact O-CG1 3.41Å; T205-I209 PolarHBondContact O-N 3.06Å; L206-I209 PolarHBondContact O-N 2.89Å; Q207-I209 VanDerWaalsContact C-N 3.29Å; Q207-I209 PolarHBondContact O-N 2.77Å; I209-M211 VanDerWaalsContact C-N 3.31Å; I209-M211 PolarHBondContact O-N 3.04Å; I209-L212 PolarHBondContact O-N 3.1Å; I209-I213 HydrophobicContact CG2-CD1 3.86Å; I209-I213 VanDerWaalsContact O-CG1 3.3Å; I209-I213 WeakPolarHBondContact O-CG1 3.45Å; I209-I213 PolarHBondContact O-N 3.03Å; I209-I213 VanDerWaalsContact O-N 3.08Å
210	I	92.1	Very high	92	Very high	34 Å²	34	28.6 Å²	28.6	17%	0.174	15%	0.151	C	C	.	.	H	α-helix	trans	-66	-38.8	-177.6	-56.2	170.6	0	0	0	110.4	Y35 L206 Q207 I213 G214 L381 V385	Y35-I210 HydrophobicContact CD2-CD1 4.05Å; Y35-I210 HydrophobicContact CE2-CB 4.48Å; Y35-I210 HydrophobicContact CE2-CD1 3.58Å; Y35-I210 HydrophobicContact CE2-CG2 4.2Å; L206-I210 HydrophobicContact CD1-CD1 3.87Å; L206-I210 HydrophobicContact CD1-CG1 4.39Å; L206-I210 HydrophobicContact CG-CD1 3.88Å; L206-I210 WeakPolarHBondContact O-CG1 3.45Å; L206-I210 PolarHBondContact O-N 3.01Å; Q207-I210 PolarHBondContact O-N 3.47Å; I210-I213 PolarHBondContact O-N 3.33Å; I210-G214 PolarHBondContact O-N 3.05Å; I210-L381 HydrophobicContact CG2-CD1 3.86Å; I210-L381 HydrophobicContact CG2-CD2 4.33Å; I210-L381 HydrophobicContact CG2-CG 4.17Å; I210-V385 HydrophobicContact CB-CG2 4.02Å; I210-V385 HydrophobicContact CG2-CG2 3.33Å
211	M	92.2	Very high	92.7	Very high	1 Å²	1	32 Å²	32	1%	0.005	17%	0.166	C	C	.	.	H	α-helix	trans	-62.3	-45.2	177	-176.2	173.6	81.6	0	0	113.3	F75 I79 Y84 Q207 T208 I209 S215 V385	F75-M211 HydrophobicContact CD1-CE 4.09Å; F75-M211 HydrophobicContact CE1-CE 3.46Å; F75-M211 VanDerWaalsContact CE1-CE 3.46Å; F75-M211 HydrophobicContact CZ-CE 4.37Å; I79-M211 HydrophobicContact CB-CE 4.25Å; I79-M211 HydrophobicContact CG2-CE 3.65Å; I79-M211 HydrophobicContact CG2-SD 4.37Å; Y84-M211 HydrophobicContact CE2-CG 3.84Å; Y84-M211 HydrophobicContact CE2-SD 3.59Å; Y84-M211 VanDerWaalsContact CE2-SD 3.59Å; Y84-M211 WeakPolarHBondContact OH-CG 3.23Å; Q207-M211 WeakPolarHBondContact O-CB 3.31Å; Q207-M211 PolarHBondContact O-N 2.91Å; T208-M211 PolarHBondContact O-N 3.41Å; I209-M211 VanDerWaalsContact C-N 3.31Å; I209-M211 PolarHBondContact O-N 3.04Å; M211-S215 VanDerWaalsContact O-CB 3.3Å; M211-S215 WeakPolarHBondContact O-CB 3.27Å; M211-S215 PolarHBondContact O-N 2.66Å; M211-S215 PolarHBondContact O-OG 3.48Å; M211-V385 HydrophobicContact CB-CG1 3.47Å; M211-V385 VanDerWaalsContact CB-CG1 3.47Å; M211-V385 HydrophobicContact CG-CG1 3.9Å
212	L	94.6	Very high	93.2	Very high	24 Å²	24	32 Å²	32	13%	0.126	17%	0.166	C	C	.	.	H	α-helix	trans	-63.3	-49.5	175.3	-69.8	172.8	0	0	0	110.6	F75 T208 I209 G214 S215 F216 L320 L323 L327	F75-L212 HydrophobicContact CE1-CD2 4.08Å; F75-L212 HydrophobicContact CE1-CG 4.5Å; F75-L212 HydrophobicContact CZ-CD2 4.09Å; T208-L212 HydrophobicContact CG2-CD1 3.89Å; T208-L212 HydrophobicContact CG2-CG 4.34Å; T208-L212 WeakPolarHBondContact O-CB 3.42Å; T208-L212 VanDerWaalsContact O-CG 3.23Å; T208-L212 WeakPolarHBondContact O-CG 3.42Å; T208-L212 PolarHBondContact O-N 3.12Å; I209-L212 PolarHBondContact O-N 3.1Å; L212-G214 PolarHBondContact O-N 3.04Å; L212-S215 PolarHBondContact O-N 2.66Å; L212-F216 HydrophobicContact CB-CD2 4.47Å; L212-F216 HydrophobicContact CB-CE2 4.42Å; L212-F216 WeakPolarHBondContact O-CD2 3.47Å; L212-F216 PolarHBondContact O-N 3.49Å; L212-L320 HydrophobicContact CD1-CD2 3.67Å; L212-L323 HydrophobicContact CD2-CD1 3.83Å; L212-L327 HydrophobicContact CD2-CD1 3.77Å
213	I	95	Very high	93.7	Very high	93 Å²	93	30.5 Å²	30.5	48%	0.477	16%	0.161	S	C	.	.	H	α-helix	trans	-57	-51.2	179.5	-67.7	167.7	0	0	0	110.8	I209 I210 S215 F216 I217	I209-I213 HydrophobicContact CG2-CD1 3.86Å; I209-I213 VanDerWaalsContact O-CG1 3.3Å; I209-I213 WeakPolarHBondContact O-CG1 3.45Å; I209-I213 PolarHBondContact O-N 3.03Å; I209-I213 VanDerWaalsContact O-N 3.08Å; I210-I213 PolarHBondContact O-N 3.33Å; I213-S215 VanDerWaalsContact C-N 3.31Å; I213-S215 PolarHBondContact O-N 3.44Å; I213-F216 PolarHBondContact O-N 3.1Å; I213-I217 HydrophobicContact CG2-CD1 3.88Å; I213-I217 VanDerWaalsContact O-CG1 3.31Å; I213-I217 WeakPolarHBondContact O-CG1 3.48Å; I213-I217 PolarHBondContact O-N 2.87Å
214	G	93.7	Very high	94.2	Very high	2 Å²	2	35.9 Å²	35.9	2%	0.021	19%	0.189	C	C	.	.	H	α-helix	trans	-62.9	-37	-179.7	0	0	0	0	0	113.1	I210 L212 I217 L218 M382	I210-G214 PolarHBondContact O-N 3.05Å; L212-G214 PolarHBondContact O-N 3.04Å; G214-I217 PolarHBondContact O-N 3.17Å; G214-L218 PolarHBondContact O-N 3.26Å; G214-M382 WeakPolarHBondContact CA-SD 3.46Å
215	S	94.9	Very high	94.5	Very high	0 Å²	0	40.7 Å²	40.7	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-69.8	-38.4	176	-54.9	0	0	0	0	112.6	Y84 M211 L212 I213 I217 L218 M219	Y84-S215 WeakPolarHBondContact CE1-OG 3.37Å; Y84-S215 PolarHBondContact OH-OG 3.19Å; M211-S215 VanDerWaalsContact O-CB 3.3Å; M211-S215 WeakPolarHBondContact O-CB 3.27Å; M211-S215 PolarHBondContact O-N 2.66Å; M211-S215 PolarHBondContact O-OG 3.48Å; L212-S215 PolarHBondContact O-N 2.66Å; I213-S215 VanDerWaalsContact C-N 3.31Å; I213-S215 PolarHBondContact O-N 3.44Å; S215-I217 VanDerWaalsContact C-N 3.31Å; S215-L218 PolarHBondContact O-N 3.15Å; S215-M219 WeakPolarHBondContact O-CB 3.26Å; S215-M219 PolarHBondContact O-N 3.28Å
216	F	96.6	Very high	94.8	Very high	91 Å²	91	40.5 Å²	40.5	40%	0.399	21%	0.211	S	C	.	.	H	α-helix	trans	-63	-39.9	173.9	-84.5	-66.6	0	0	0	111.4	L212 I213 M219 G220 L323 L327	L212-F216 HydrophobicContact CB-CD2 4.47Å; L212-F216 HydrophobicContact CB-CE2 4.42Å; L212-F216 WeakPolarHBondContact O-CD2 3.47Å; L212-F216 PolarHBondContact O-N 3.49Å; I213-F216 PolarHBondContact O-N 3.1Å; F216-M219 HydrophobicContact CD1-CE 3.88Å; F216-M219 HydrophobicContact CE1-CE 4.43Å; F216-M219 PolarHBondContact O-N 3.26Å; F216-G220 PolarHBondContact O-N 3.31Å; F216-L323 HydrophobicContact CE2-CD1 4.3Å; F216-L323 HydrophobicContact CZ-CD1 4.1Å; F216-L323 HydrophobicContact CZ-CD2 4.01Å; F216-L327 HydrophobicContact CB-CD2 4.48Å; F216-L327 HydrophobicContact CD1-CD2 3.64Å; F216-L327 HydrophobicContact CD2-CD2 4.31Å; F216-L327 HydrophobicContact CE1-CD2 3.83Å; F216-L327 HydrophobicContact CE2-CD1 4.21Å; F216-L327 HydrophobicContact CE2-CD2 4.45Å; F216-L327 HydrophobicContact CG-CD2 3.88Å; F216-L327 HydrophobicContact CZ-CD1 4.32Å; F216-L327 HydrophobicContact CZ-CD2 4.22Å
217	I	96.2	Very high	95	Very high	55 Å²	55	41.2 Å²	41.2	28%	0.282	23%	0.227	S	C	.	.	H	α-helix	trans	-62.6	-47.9	174.7	-66.6	165.9	0	0	0	110	I213 G214 S215 M219 G220 F221 L378	I213-I217 HydrophobicContact CG2-CD1 3.88Å; I213-I217 VanDerWaalsContact O-CG1 3.31Å; I213-I217 WeakPolarHBondContact O-CG1 3.48Å; I213-I217 PolarHBondContact O-N 2.87Å; G214-I217 PolarHBondContact O-N 3.17Å; S215-I217 VanDerWaalsContact C-N 3.31Å; I217-M219 VanDerWaalsContact C-N 3.32Å; I217-M219 PolarHBondContact O-N 3.28Å; I217-G220 PolarHBondContact O-N 3.13Å; I217-F221 HydrophobicContact CG2-CD2 3.73Å; I217-F221 HydrophobicContact CG2-CE2 3.57Å; I217-F221 VanDerWaalsContact O-CD2 3.29Å; I217-F221 WeakPolarHBondContact O-CD2 3.28Å; I217-F221 PolarHBondContact O-N 3.07Å; I217-F221 VanDerWaalsContact O-N 3.09Å; I217-L378 HydrophobicContact CD1-CD2 4.27Å; I217-L378 HydrophobicContact CG2-CD1 3.88Å
218	L	96	Very high	95.3	Very high	0 Å²	0	42.2 Å²	42.2	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-56.9	-47.1	176.8	-170.8	54.2	0	0	0	112	G214 S215 G220 F221 A222 Y366 M369 V370 L373 M374	G214-L218 PolarHBondContact O-N 3.26Å; S215-L218 PolarHBondContact O-N 3.15Å; L218-G220 VanDerWaalsContact C-N 3.28Å; L218-G220 PolarHBondContact O-N 3.31Å; L218-F221 PolarHBondContact O-N 2.87Å; L218-A222 VanDerWaalsContact O-CB 3.26Å; L218-A222 WeakPolarHBondContact O-CB 3.49Å; L218-A222 PolarHBondContact O-N 3.21Å; L218-Y366 HydrophobicContact CD2-CD2 4.42Å; L218-Y366 HydrophobicContact CD2-CE1 3.91Å; L218-Y366 HydrophobicContact CD2-CE2 3.69Å; L218-Y366 VanDerWaalsContact CD2-CZ 3.4Å; L218-Y366 WeakPolarHBondContact CD2-OH 3.43Å; L218-M369 HydrophobicContact CD1-CB 4.32Å; L218-M369 HydrophobicContact CD2-CB 4.24Å; L218-V370 HydrophobicContact CD2-CG2 3.86Å; L218-L373 HydrophobicContact CD1-CD2 4.46Å; L218-M374 HydrophobicContact CB-CE 3.29Å; L218-M374 HydrophobicContact CD1-CE 3.56Å; L218-M374 HydrophobicContact CD1-CG 3.9Å; L218-M374 HydrophobicContact CD2-CE 4.17Å; L218-M374 HydrophobicContact CG-CE 3.81Å
219	M	96.4	Very high	95.3	Very high	41 Å²	41	46.2 Å²	46.2	20%	0.202	26%	0.255	C	S	.	.	H	α-helix	trans	-56.3	-45.1	178.8	178.9	-166.9	79.3	0	0	110.7	S215 F216 I217 A222 F223 F326 L327	S215-M219 WeakPolarHBondContact O-CB 3.26Å; S215-M219 PolarHBondContact O-N 3.28Å; F216-M219 HydrophobicContact CD1-CE 3.88Å; F216-M219 HydrophobicContact CE1-CE 4.43Å; F216-M219 PolarHBondContact O-N 3.26Å; I217-M219 VanDerWaalsContact C-N 3.32Å; I217-M219 PolarHBondContact O-N 3.28Å; M219-A222 PolarHBondContact O-N 3.41Å; M219-F223 HydrophobicContact CG-CD2 3.76Å; M219-F223 HydrophobicContact CG-CE2 3.82Å; M219-F223 WeakPolarHBondContact O-CD2 3.36Å; M219-F223 PolarHBondContact O-N 3.33Å; M219-F326 WeakPolarHBondContact CG-O 3.31Å; M219-F326 HydrophobicContact SD-CB 3.62Å; M219-L327 HydrophobicContact CB-CD2 4.44Å; M219-L327 HydrophobicContact SD-CD2 4.11Å
220	G	96.3	Very high	95.3	Very high	42 Å²	42	50.2 Å²	50.2	43%	0.433	27%	0.271	S	S	.	.	H	α-helix	trans	-58.8	-48.3	176.3	0	0	0	0	0	113	F216 I217 L218 N224	F216-G220 PolarHBondContact O-N 3.31Å; I217-G220 PolarHBondContact O-N 3.13Å; L218-G220 VanDerWaalsContact C-N 3.28Å; L218-G220 PolarHBondContact O-N 3.31Å; G220-N224 WeakPolarHBondContact O-CB 3.36Å; G220-N224 PolarHBondContact O-N 3.06Å; G220-N224 VanDerWaalsContact O-N 3.12Å
221	F	96.2	Very high	95.5	Very high	76 Å²	76	50 Å²	50	33%	0.333	27%	0.273	S	S	.	.	H	α-helix	trans	-62.3	-45.7	175.3	-79.9	-74.6	0	0	0	112	I217 L218 F223 N224 E225 L373 P375 L378	I217-F221 HydrophobicContact CG2-CD2 3.73Å; I217-F221 HydrophobicContact CG2-CE2 3.57Å; I217-F221 VanDerWaalsContact O-CD2 3.29Å; I217-F221 WeakPolarHBondContact O-CD2 3.28Å; I217-F221 PolarHBondContact O-N 3.07Å; I217-F221 VanDerWaalsContact O-N 3.09Å; L218-F221 PolarHBondContact O-N 2.87Å; F221-F223 PolarHBondContact O-N 3.21Å; F221-N224 WeakPolarHBondContact O-CB 3.45Å; F221-N224 PolarHBondContact O-N 2.95Å; F221-E225 PolarHBondContact O-N 3.39Å; F221-L373 HydrophobicContact CB-CD2 3.87Å; F221-L373 HydrophobicContact CB-CG 3.99Å; F221-P375 HydrophobicContact CZ-CG 4.34Å; F221-L378 HydrophobicContact CE2-CD1 4.38Å
222	A	96.9	Very high	95.7	Very high	0 Å²	0	50 Å²	50	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-58.5	-48.2	-178.2	0	0	0	0	0	111.6	L218 M219 N224 E225 V226 I334 M369 L373	L218-A222 VanDerWaalsContact O-CB 3.26Å; L218-A222 WeakPolarHBondContact O-CB 3.49Å; L218-A222 PolarHBondContact O-N 3.21Å; M219-A222 PolarHBondContact O-N 3.41Å; A222-N224 VanDerWaalsContact C-N 3.34Å; A222-N224 PolarHBondContact O-N 3.26Å; A222-E225 PolarHBondContact O-N 3.12Å; A222-V226 WeakPolarHBondContact O-CG2 3.19Å; A222-V226 PolarHBondContact O-N 3.08Å; A222-I334 HydrophobicContact CB-CB 4.44Å; A222-I334 HydrophobicContact CB-CD1 3.77Å; A222-I334 HydrophobicContact CB-CG2 3.97Å; A222-M369 HydrophobicContact CB-CE 3.38Å; A222-L373 HydrophobicContact CB-CD2 4.22Å
223	F	97.4	Very high	95.8	Very high	33 Å²	33	50.8 Å²	50.8	15%	0.145	28%	0.279	C	S	.	.	H	α-helix	trans	-67.8	-33.4	177.9	-85.7	-70.5	0	0	0	113	M219 F221 V226 G227 G228 Y229 F232 M330 I334	M219-F223 HydrophobicContact CG-CD2 3.76Å; M219-F223 HydrophobicContact CG-CE2 3.82Å; M219-F223 WeakPolarHBondContact O-CD2 3.36Å; M219-F223 PolarHBondContact O-N 3.33Å; F221-F223 PolarHBondContact O-N 3.21Å; F223-V226 HydrophobicContact CD1-CG2 4.37Å; F223-V226 WeakPolarHBondContact O-CG2 3.44Å; F223-G227 PolarHBondContact O-N 2.86Å; F223-G228 PolarHBondContact O-N 2.77Å; F223-Y229 AromaticContact CE1-CD2 3.9Å; F223-Y229 HydrophobicContact CE1-CD2 3.9Å; F223-Y229 HydrophobicContact CZ-CD2 4.23Å; F223-F232 HydrophobicContact CE1-CB 4.23Å; F223-F232 HydrophobicContact CE1-CD1 4.05Å; F223-F232 HydrophobicContact CE1-CG 4.08Å; F223-M330 HydrophobicContact CE2-CB 4.37Å; F223-M330 HydrophobicContact CE2-SD 4.32Å; F223-M330 HydrophobicContact CZ-CB 4.06Å; F223-M330 HydrophobicContact CZ-CG 4.42Å; F223-M330 HydrophobicContact CZ-SD 3.72Å; F223-I334 HydrophobicContact CD1-CD1 4.04Å; F223-I334 HydrophobicContact CD2-CD1 4.19Å; F223-I334 HydrophobicContact CE1-CD1 4.05Å; F223-I334 HydrophobicContact CE2-CD1 4.2Å; F223-I334 HydrophobicContact CG-CD1 4.11Å; F223-I334 HydrophobicContact CZ-CD1 4.13Å
224	N	96.8	Very high	95.8	Very high	119 Å²	119	52.5 Å²	52.5	64%	0.636	29%	0.285	S	S	*	.	H	α-helix	trans	-63.6	-45.1	176.2	-175.6	74.9	0	0	0	111.6	G220 F221 A222 V226 G227	G220-N224 WeakPolarHBondContact O-CB 3.36Å; G220-N224 PolarHBondContact O-N 3.06Å; G220-N224 VanDerWaalsContact O-N 3.12Å; F221-N224 WeakPolarHBondContact O-CB 3.45Å; F221-N224 PolarHBondContact O-N 2.95Å; A222-N224 VanDerWaalsContact C-N 3.34Å; A222-N224 PolarHBondContact O-N 3.26Å; N224-V226 VanDerWaalsContact C-N 3.35Å; N224-V226 PolarHBondContact O-N 3.3Å; N224-G227 PolarHBondContact O-N 2.92Å
225	E	96.3	Very high	96	Very high	101 Å²	101	56.3 Å²	56.3	47%	0.472	30%	0.301	S	S	.	.	H	α-helix	trans	-63.5	-37.3	179.5	-71.6	-54.6	131	0	0	113.5	F221 A222 G227 L338 L373	F221-E225 PolarHBondContact O-N 3.39Å; A222-E225 PolarHBondContact O-N 3.12Å; E225-G227 VanDerWaalsContact C-N 3.29Å; E225-G227 PolarHBondContact O-N 3.44Å; E225-L338 HydrophobicContact CB-CD1 4.13Å; E225-L338 HydrophobicContact CB-CD2 4.3Å; E225-L373 HydrophobicContact CG-CD1 3.38Å; E225-L373 HydrophobicContact CG-CD2 4.19Å; E225-L373 HydrophobicContact CG-CG 4.42Å
226	V	96.2	Very high	96.1	Very high	1 Å²	1	56.3 Å²	56.3	1%	0.006	30%	0.301	C	S	.	.	H	α-helix	trans	-81.9	-7.7	178.8	-61.6	0	0	0	0	113.2	A222 F223 N224 S231 F232 K235 I334 I337 L338	A222-V226 WeakPolarHBondContact O-CG2 3.19Å; A222-V226 PolarHBondContact O-N 3.08Å; F223-V226 HydrophobicContact CD1-CG2 4.37Å; F223-V226 WeakPolarHBondContact O-CG2 3.44Å; N224-V226 VanDerWaalsContact C-N 3.35Å; N224-V226 PolarHBondContact O-N 3.3Å; V226-S231 VanDerWaalsContact O-CB 3.29Å; V226-S231 WeakPolarHBondContact O-CB 3.21Å; V226-S231 PolarHBondContact O-OG 2.73Å; V226-S231 VanDerWaalsContact O-OG 3.13Å; V226-F232 HydrophobicContact CG2-CB 3.91Å; V226-K235 PolarHBondContact O-NZ 3.48Å; V226-I334 HydrophobicContact CG1-CB 4.37Å; V226-I334 HydrophobicContact CG1-CG1 4.23Å; V226-I334 HydrophobicContact CG1-CG2 3.55Å; V226-I334 HydrophobicContact CG2-CD1 4.2Å; V226-I334 HydrophobicContact CG2-CG1 4.24Å; V226-I337 HydrophobicContact CG1-CB 4.44Å; V226-I337 HydrophobicContact CG1-CD1 4.19Å; V226-I337 HydrophobicContact CG1-CG2 4.15Å; V226-L338 HydrophobicContact CG1-CD2 4.12Å; V226-L338 HydrophobicContact CG1-CG 4.36Å
227	G	95.3	Very high	96.1	Very high	55 Å²	55	55 Å²	55	57%	0.567	30%	0.297	S	S	*	.	T	Hydrogen-bonded Turn	trans	85.1	29.6	178.7	0	0	0	0	0	114.4	F223 N224 E225	F223-G227 PolarHBondContact O-N 2.86Å; N224-G227 PolarHBondContact O-N 2.92Å; E225-G227 VanDerWaalsContact C-N 3.29Å; E225-G227 PolarHBondContact O-N 3.44Å
228	G	95.4	Very high	96.1	Very high	27 Å²	27	57.7 Å²	57.7	28%	0.278	31%	0.312	S	S	.	.	S	Bend	trans	91.1	-178.5	177.8	0	0	0	0	0	114.7	F223 F232	F223-G228 PolarHBondContact O-N 2.77Å; G228-F232 VanDerWaalsContact O-CB 3.25Å; G228-F232 WeakPolarHBondContact O-CB 3.39Å; G228-F232 PolarHBondContact O-N 3.16Å
229	Y	93.9	Very high	96.1	Very high	89 Å²	89	57.9 Å²	57.9	35%	0.349	31%	0.313	S	S	.	.	H	α-helix	trans	-67.9	-38.7	-171.3	-171.3	-94.6	0	0	0	113.8	F223 F232 T233 M330	F223-Y229 AromaticContact CE1-CD2 3.9Å; F223-Y229 HydrophobicContact CE1-CD2 3.9Å; F223-Y229 HydrophobicContact CZ-CD2 4.23Å; Y229-F232 HydrophobicContact CD2-CD1 4.09Å; Y229-F232 HydrophobicContact CE2-CD1 4.16Å; Y229-F232 HydrophobicContact CE2-CE1 4.23Å; Y229-F232 WeakPolarHBondContact O-CB 3.16Å; Y229-F232 PolarHBondContact O-N 3.25Å; Y229-T233 HydrophobicContact CD1-CG2 4.41Å; Y229-T233 HydrophobicContact CE1-CG2 3.99Å; Y229-T233 PolarHBondContact O-N 3.23Å; Y229-M330 HydrophobicContact CE2-CE 3.8Å; Y229-M330 HydrophobicContact CE2-SD 4.24Å
230	E	93.1	Very high	96.1	Very high	170 Å²	170	59.6 Å²	59.6	79%	0.794	32%	0.323	S	S	*	.	H	α-helix	trans	-67.1	-44.6	179.6	-67.3	-178.6	175.2	0	0	111.7	F232 T233 E234	E230-F232 VanDerWaalsContact C-N 3.3Å; E230-F232 PolarHBondContact O-N 2.69Å; E230-T233 PolarHBondContact O-N 3.12Å; E230-T233 PolarHBondContact O-OG1 3.18Å; E230-E234 PolarHBondContact O-N 3.41Å
231	S	96.3	Very high	96	Very high	30 Å²	30	57.9 Å²	57.9	21%	0.21	30%	0.304	C	S	.	.	H	α-helix	trans	-69.7	-30.9	176.3	-169	0	0	0	0	111.9	V226 K235	V226-S231 VanDerWaalsContact O-CB 3.29Å; V226-S231 WeakPolarHBondContact O-CB 3.21Å; V226-S231 PolarHBondContact O-OG 2.73Å; V226-S231 VanDerWaalsContact O-OG 3.13Å; S231-K235 VanDerWaalsContact O-CB 3.22Å; S231-K235 WeakPolarHBondContact O-CB 3.34Å; S231-K235 VanDerWaalsContact O-CG 3.24Å; S231-K235 WeakPolarHBondContact O-CG 3.43Å; S231-K235 PolarHBondContact O-N 3.26Å; S231-K235 WeakPolarHBondContact OG-CD 2.94Å; S231-K235 WeakPolarHBondContact OG-CE 3.45Å; S231-K235 PolarHBondContact OG-NZ 3.39Å
232	F	96.9	Very high	95.8	Very high	0 Å²	0	58.9 Å²	58.9	0%	0	32%	0.32	C	S	.	.	H	α-helix	trans	-58.3	-48.7	174.1	157.4	-110.1	0	0	0	112.6	F223 V226 G228 Y229 E230 E234 K235 Y236 F263 M330 M333 I334 I337	F223-F232 HydrophobicContact CE1-CB 4.23Å; F223-F232 HydrophobicContact CE1-CD1 4.05Å; F223-F232 HydrophobicContact CE1-CG 4.08Å; V226-F232 HydrophobicContact CG2-CB 3.91Å; G228-F232 VanDerWaalsContact O-CB 3.25Å; G228-F232 WeakPolarHBondContact O-CB 3.39Å; G228-F232 PolarHBondContact O-N 3.16Å; Y229-F232 HydrophobicContact CD2-CD1 4.09Å; Y229-F232 HydrophobicContact CE2-CD1 4.16Å; Y229-F232 HydrophobicContact CE2-CE1 4.23Å; Y229-F232 WeakPolarHBondContact O-CB 3.16Å; Y229-F232 PolarHBondContact O-N 3.25Å; E230-F232 VanDerWaalsContact C-N 3.3Å; E230-F232 PolarHBondContact O-N 2.69Å; F232-E234 PolarHBondContact O-N 2.78Å; F232-K235 PolarHBondContact O-N 3.31Å; F232-Y236 VanDerWaalsContact O-CB 3.3Å; F232-Y236 WeakPolarHBondContact O-CB 3.4Å; F232-Y236 PolarHBondContact O-N 3.18Å; F232-F263 HydrophobicContact CD1-CE1 4.44Å; F232-F263 AromaticContact CE1-CE1 3.63Å; F232-F263 HydrophobicContact CE1-CE1 3.63Å; F232-F263 HydrophobicContact CE1-CZ 4.2Å; F232-F263 AromaticContact CZ-CE1 3.96Å; F232-F263 HydrophobicContact CZ-CE1 3.96Å; F232-F263 HydrophobicContact CZ-CZ 4.33Å; F232-M330 HydrophobicContact CE1-CG 4.39Å; F232-M330 HydrophobicContact CZ-CB 4.44Å; F232-M330 HydrophobicContact CZ-CG 4.3Å; F232-M333 HydrophobicContact CE2-CB 3.55Å; F232-M333 HydrophobicContact CE2-CE 4.46Å; F232-M333 HydrophobicContact CZ-CB 3.73Å; F232-M333 HydrophobicContact CZ-CE 3.8Å; F232-M333 HydrophobicContact CZ-CG 4.41Å; F232-M333 HydrophobicContact CZ-SD 3.85Å; F232-I334 HydrophobicContact CD2-CD1 4.25Å; F232-I334 HydrophobicContact CD2-CG1 3.49Å; F232-I334 VanDerWaalsContact CD2-CG1 3.49Å; F232-I334 HydrophobicContact CE2-CG1 3.66Å; F232-I334 HydrophobicContact CG-CG1 4.46Å; F232-I337 HydrophobicContact CD2-CD1 3.69Å; F232-I337 HydrophobicContact CE2-CD1 4.21Å
233	T	95.2	Very high	95.5	Very high	41 Å²	41	61.9 Å²	61.9	25%	0.252	34%	0.339	S	S	.	.	H	α-helix	trans	-64.7	-42.9	-177.3	55	0	0	0	0	111.6	Y229 E230 M237 F263	Y229-T233 HydrophobicContact CD1-CG2 4.41Å; Y229-T233 HydrophobicContact CE1-CG2 3.99Å; Y229-T233 PolarHBondContact O-N 3.23Å; E230-T233 PolarHBondContact O-N 3.12Å; E230-T233 PolarHBondContact O-OG1 3.18Å; T233-M237 WeakPolarHBondContact O-CG 3.38Å; T233-M237 PolarHBondContact O-N 3.42Å; T233-F263 HydrophobicContact CG2-CD1 4.18Å; T233-F263 HydrophobicContact CG2-CE1 3.74Å; T233-F263 HydrophobicContact CG2-CE2 4.35Å; T233-F263 HydrophobicContact CG2-CZ 3.85Å
234	E	95.8	Very high	95.1	Very high	130 Å²	130	61.9 Å²	61.9	61%	0.607	34%	0.341	S	S	*	.	H	α-helix	trans	-64.6	-50.1	176.7	-174.6	-173.2	175.9	0	0	112	E230 F232 Y236 M237 N238	E230-E234 PolarHBondContact O-N 3.41Å; F232-E234 PolarHBondContact O-N 2.78Å; E234-Y236 VanDerWaalsContact C-N 3.32Å; E234-Y236 PolarHBondContact O-N 3.12Å; E234-M237 PolarHBondContact O-N 2.87Å; E234-N238 PolarHBondContact O-N 3.23Å; E234-N238 PolarHBondContact O-ND2 3.14Å
235	K	97.7	Very high	94.7	Very high	82 Å²	82	62.6 Å²	62.6	36%	0.357	34%	0.341	S	S	.	.	H	α-helix	trans	-65.7	-35.5	-178.4	-75	174.9	176.4	167.3	0	112.3	V226 S231 F232 M237 N238 A239 I337	V226-K235 PolarHBondContact O-NZ 3.48Å; S231-K235 VanDerWaalsContact O-CB 3.22Å; S231-K235 WeakPolarHBondContact O-CB 3.34Å; S231-K235 VanDerWaalsContact O-CG 3.24Å; S231-K235 WeakPolarHBondContact O-CG 3.43Å; S231-K235 PolarHBondContact O-N 3.26Å; S231-K235 WeakPolarHBondContact OG-CD 2.94Å; S231-K235 WeakPolarHBondContact OG-CE 3.45Å; S231-K235 PolarHBondContact OG-NZ 3.39Å; F232-K235 PolarHBondContact O-N 3.31Å; K235-M237 VanDerWaalsContact C-N 3.31Å; K235-M237 PolarHBondContact O-N 3.47Å; K235-N238 CarbonylContact O-C 3.59Å; K235-N238 PolarHBondContact O-N 3.48Å; K235-N238 VanDerWaalsContact O-N 3.15Å; K235-A239 PolarHBondContact O-N 2.87Å; K235-A239 VanDerWaalsContact O-N 3.15Å; K235-I337 HydrophobicContact CB-CD1 3.9Å; K235-I337 HydrophobicContact CB-CG1 4.22Å; K235-I337 HydrophobicContact CB-CG2 3.79Å; K235-I337 HydrophobicContact CD-CG2 4.2Å
236	Y	97.7	Very high	94	Very high	0 Å²	0	59 Å²	59	0%	0	33%	0.33	C	S	.	.	H	α-helix	trans	-58.2	-45.9	176.5	-179.3	-100.4	0	0	0	111.1	G91 A92 G95 F232 E234 N238 A239 P258 F263 M333 R336	G91-Y236 PolarHBondContact O-OH 2.88Å; A92-Y236 PolarHBondContact O-OH 2.95Å; G95-Y236 PolarHBondContact N-OH 3.48Å; F232-Y236 VanDerWaalsContact O-CB 3.3Å; F232-Y236 WeakPolarHBondContact O-CB 3.4Å; F232-Y236 PolarHBondContact O-N 3.18Å; E234-Y236 VanDerWaalsContact C-N 3.32Å; E234-Y236 PolarHBondContact O-N 3.12Å; Y236-N238 PolarHBondContact O-N 3.48Å; Y236-A239 WeakPolarHBondContact O-CB 3.32Å; Y236-A239 PolarHBondContact O-N 2.89Å; Y236-A239 VanDerWaalsContact O-N 3.13Å; Y236-P258 HydrophobicContact CD1-CB 4.19Å; Y236-P258 HydrophobicContact CE1-CB 3.76Å; Y236-P258 HydrophobicContact CE1-CG 4.47Å; Y236-P258 WeakPolarHBondContact O-CG 3.28Å; Y236-F263 AromaticContact CD1-CE2 3.91Å; Y236-F263 HydrophobicContact CD1-CE2 3.91Å; Y236-F263 AromaticContact CD1-CZ 3.88Å; Y236-F263 HydrophobicContact CD1-CZ 3.88Å; Y236-F263 HydrophobicContact CG-CZ 4.18Å; Y236-M333 HydrophobicContact CD1-CE 3.64Å; Y236-M333 HydrophobicContact CD2-CB 3.66Å; Y236-M333 HydrophobicContact CD2-CE 3.89Å; Y236-M333 HydrophobicContact CD2-CG 4.16Å; Y236-M333 HydrophobicContact CE1-CE 3.63Å; Y236-M333 HydrophobicContact CE2-CB 3.67Å; Y236-M333 HydrophobicContact CE2-CE 3.88Å; Y236-M333 HydrophobicContact CE2-CG 3.74Å; Y236-M333 HydrophobicContact CG-CE 3.76Å; Y236-R336 HydrophobicContact CE2-CB 4.47Å
237	M	96.8	Very high	93.4	Very high	62 Å²	62	62.7 Å²	62.7	31%	0.305	35%	0.35	S	S	.	.	H	α-helix	trans	-65.1	-22.2	-179.9	-66.3	-55.2	-63.1	0	0	113.5	T233 E234 K235 P258 R259 F263	T233-M237 WeakPolarHBondContact O-CG 3.38Å; T233-M237 PolarHBondContact O-N 3.42Å; E234-M237 PolarHBondContact O-N 2.87Å; K235-M237 VanDerWaalsContact C-N 3.31Å; K235-M237 PolarHBondContact O-N 3.47Å; M237-P258 HydrophobicContact CE-CB 4.42Å; M237-P258 HydrophobicContact SD-CB 4.11Å; M237-R259 WeakPolarHBondContact CE-O 3.38Å; M237-F263 HydrophobicContact CG-CE2 4.26Å; M237-F263 HydrophobicContact SD-CE2 4.16Å
238	N	96.1	Very high	92.9	Very high	112 Å²	112	68.5 Å²	68.5	60%	0.599	37%	0.368	S	S	*	.	T	Hydrogen-bonded Turn	trans	-98.1	1.2	178.3	-66.2	-56.1	0	0	0	113.7	E234 K235 Y236 I240	E234-N238 PolarHBondContact O-N 3.23Å; E234-N238 PolarHBondContact O-ND2 3.14Å; K235-N238 CarbonylContact O-C 3.59Å; K235-N238 PolarHBondContact O-N 3.48Å; K235-N238 VanDerWaalsContact O-N 3.15Å; Y236-N238 PolarHBondContact O-N 3.48Å; N238-I240 VanDerWaalsContact C-N 3.33Å; N238-I240 PolarHBondContact O-N 3.44Å
239	A	96.1	Very high	92.3	Very high	4 Å²	4	70.9 Å²	70.9	3%	0.033	37%	0.374	C	S	.	.			trans	-80.5	77.2	-176.6	0	0	0	0	0	112	K235 Y236 R336 I337 T340	K235-A239 PolarHBondContact O-N 2.87Å; K235-A239 VanDerWaalsContact O-N 3.15Å; Y236-A239 WeakPolarHBondContact O-CB 3.32Å; Y236-A239 PolarHBondContact O-N 2.89Å; Y236-A239 VanDerWaalsContact O-N 3.13Å; A239-R336 HydrophobicContact CB-CG 3.84Å; A239-R336 PolarHBondContact O-NE 3.24Å; A239-R336 VanDerWaalsContact O-NE 3.12Å; A239-I337 HydrophobicContact CB-CG1 4.35Å; A239-T340 VanDerWaalsContact C-CG2 3.45Å; A239-T340 HydrophobicContact CB-CG2 4.23Å
240	I	95.3	Very high	91.7	Very high	78 Å²	78	72.3 Å²	72.3	40%	0.4	39%	0.392	S	S	.	.			trans	-106.8	131.1	179.1	-65.4	169.4	0	0	0	109.6	N238 Y256 T257 T340	N238-I240 VanDerWaalsContact C-N 3.33Å; N238-I240 PolarHBondContact O-N 3.44Å; I240-Y256 HydrophobicContact CG2-CD2 3.77Å; I240-Y256 HydrophobicContact CG2-CE2 4.1Å; I240-T257 HydrophobicContact CD1-CG2 4.05Å; I240-T257 HydrophobicContact CG1-CG2 4.37Å; I240-T340 WeakPolarHBondContact O-CG2 3.21Å
241	P	94.1	Very high	91.4	Very high	6 Å²	6	64.9 Å²	64.9	4%	0.039	36%	0.358	C	S	.	.			trans	-64.9	149.5	178.1	30.8	-39.4	0	0	0	111.6	V243 V244 A344	P241-V243 VanDerWaalsContact C-N 3.32Å; P241-V243 PolarHBondContact O-N 3.45Å; P241-V244 HydrophobicContact CG-CG1 3.94Å; P241-A344 WeakPolarHBondContact CG-O 3.31Å
242	S	92.6	Very high	90.9	Very high	97 Å²	97	66.8 Å²	66.8	68%	0.678	37%	0.371	S	S	*	.	S	Bend	trans	-70.8	-28.6	-178.9	-50.9	0	0	0	0	112.6	D341	S242-D341 VanDerWaalsContact CB-OD1 3.31Å; S242-D341 WeakPolarHBondContact CB-OD1 3.45Å; S242-D341 PolarHBondContact N-OD1 3.48Å; S242-D341 PolarHBondContact OG-OD1 3.06Å; S242-D341 PolarHBondContact OG-OD2 2.98Å
243	V	90.5	Very high	90.5	Very high	63 Å²	63	69.1 Å²	69.1	38%	0.382	39%	0.39	S	S	.	.			trans	-111	107.5	-179.5	-174.1	0	0	0	0	109.4	P241 V347 E350	P241-V243 VanDerWaalsContact C-N 3.32Å; P241-V243 PolarHBondContact O-N 3.45Å; V243-V347 HydrophobicContact CG1-CB 4.5Å; V243-V347 HydrophobicContact CG1-CG2 4.02Å; V243-E350 HydrophobicContact CB-CG 4.43Å; V243-E350 HydrophobicContact CG1-CG 4.13Å
244	V	89.4	Confident	90.2	Very high	32 Å²	32	71.3 Å²	71.3	19%	0.194	41%	0.407	C	S	.	.			trans	-119.8	-11.1	-178.5	-66.8	0	0	0	0	113.5	P241 Y256	P241-V244 HydrophobicContact CG-CG1 3.94Å; V244-Y256 HydrophobicContact CB-CD1 4.02Å; V244-Y256 HydrophobicContact CB-CE1 3.8Å; V244-Y256 HydrophobicContact CB-CG 4.46Å; V244-Y256 HydrophobicContact CG1-CD1 3.77Å; V244-Y256 HydrophobicContact CG1-CD2 3.81Å; V244-Y256 HydrophobicContact CG1-CE1 3.88Å; V244-Y256 HydrophobicContact CG1-CE2 3.93Å; V244-Y256 HydrophobicContact CG1-CG 3.71Å
245	E	87.4	Confident	89.7	Confident	135 Å²	135	66.8 Å²	66.8	63%	0.631	39%	0.39	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-126.8	135.8	176	-67	-178.6	173.7	0	0	108.7	T250	E245-T250 HydrophobicContact CG-CG2 4.49Å
246	G	83.1	Confident	89.3	Confident	25 Å²	25	65 Å²	65	26%	0.258	38%	0.381	S	S	.	.	E	Extended strand (participates in β ladder)	trans	174.8	166.9	-176.1	0	0	0	0	0	111.3	N248 L249	G246-N248 PolarHBondContact O-N 3.37Å; G246-N248 VanDerWaalsContact O-N 3.12Å; G246-L249 PolarHBondContact N-O 3.37Å; G246-L249 WeakPolarHBondContact O-CB 3.3Å; G246-L249 PolarHBondContact O-N 3.44Å
247	D	83.6	Confident	89.1	Confident	78 Å²	78	67.3 Å²	67.3	42%	0.417	40%	0.395	S	S	.	.	T	Hydrogen-bonded Turn	trans	55.9	28.5	178.1	-54.7	-24.2	0	0	0	115.1	L249 S349	D247-L249 HydrophobicContact CB-CD1 4.43Å; D247-L249 PolarHBondContact O-N 3.18Å; D247-S349 VanDerWaalsContact CG-OG 3.24Å; D247-S349 WeakPolarHBondContact OD1-CB 3.15Å; D247-S349 PolarHBondContact OD1-OG 3.08Å; D247-S349 VanDerWaalsContact OD2-CB 3.31Å; D247-S349 WeakPolarHBondContact OD2-CB 3.28Å; D247-S349 PolarHBondContact OD2-N 3.34Å; D247-S349 PolarHBondContact OD2-OG 3.29Å
248	N	83.6	Confident	89	Confident	177 Å²	177	64.9 Å²	64.9	95%	0.947	38%	0.384	S	S	*	.	T	Hydrogen-bonded Turn	trans	58.6	24.6	-171.2	-58.5	-42.8	0	0	0	114.2	G246	G246-N248 PolarHBondContact O-N 3.37Å; G246-N248 VanDerWaalsContact O-N 3.12Å
249	L	82.6	Confident	88.9	Confident	78 Å²	78	63 Å²	63	41%	0.408	37%	0.369	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.8	135.6	177.8	-62.9	168.6	0	0	0	110.1	G246 D247 I251 P348 L512	G246-L249 PolarHBondContact N-O 3.37Å; G246-L249 WeakPolarHBondContact O-CB 3.3Å; G246-L249 PolarHBondContact O-N 3.44Å; D247-L249 HydrophobicContact CB-CD1 4.43Å; D247-L249 PolarHBondContact O-N 3.18Å; L249-I251 HydrophobicContact CB-CD1 4.3Å; L249-P348 HydrophobicContact CD1-CG 4.31Å; L249-L512 HydrophobicContact CD1-CD2 4.21Å
250	T	82.1	Confident	88.7	Confident	118 Å²	118	71.7 Å²	71.7	72%	0.724	41%	0.408	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-103.7	106.8	169.5	-45.8	0	0	0	0	108	E245	E245-T250 HydrophobicContact CG-CG2 4.49Å
251	I	85.8	Confident	88.7	Confident	15 Å²	15	69.6 Å²	69.6	8%	0.077	40%	0.398	C	S	.	.			trans	-80.1	137.6	-177.6	-54	-60.6	0	0	0	109.8	L249 C255 Y256 V346 L512	L249-I251 HydrophobicContact CB-CD1 4.3Å; I251-C255 HydrophobicContact CG2-CB 3.7Å; I251-Y256 HydrophobicContact CG2-CD1 4.41Å; I251-V346 HydrophobicContact CB-CG2 4.46Å; I251-V346 HydrophobicContact CG1-CG2 4.43Å; I251-V346 HydrophobicContact CG2-CB 4.19Å; I251-V346 HydrophobicContact CG2-CG2 4.26Å; I251-L512 HydrophobicContact CD1-CD2 3.67Å
252	S	87.3	Confident	88.7	Confident	70 Å²	70	69.3 Å²	69.3	49%	0.49	40%	0.396	S	S	.	.			trans	-60.4	138.4	176.1	178.6	0	0	0	0	111.5	S254 C255	S252-S254 PolarHBondContact O-N 3.43Å; S252-S254 VanDerWaalsContact O-N 3.11Å; S252-S254 PolarHBondContact OG-OG 3.03Å; S252-C255 VanDerWaalsContact O-CB 3.29Å; S252-C255 WeakPolarHBondContact O-CB 3.4Å; S252-C255 PolarHBondContact O-N 3.05Å
253	A	88.6	Confident	88.9	Confident	48 Å²	48	66.5 Å²	66.5	40%	0.397	37%	0.372	S	S	.	.	H	α-helix	trans	-51.7	-37.8	176.5	0	0	0	0	0	113.2	C255 Y256 T257	A253-C255 PolarHBondContact O-N 2.76Å; A253-Y256 VanDerWaalsContact CA-CE1 3.44Å; A253-Y256 VanDerWaalsContact CA-CZ 3.46Å; A253-Y256 HydrophobicContact CB-CE1 4.38Å; A253-Y256 HydrophobicContact CB-CE2 4.42Å; A253-Y256 PolarHBondContact O-N 2.85Å; A253-Y256 VanDerWaalsContact O-N 3.13Å; A253-T257 WeakPolarHBondContact O-CG2 3.3Å; A253-T257 PolarHBondContact O-N 3.35Å; A253-T257 PolarHBondContact O-OG1 3.21Å
254	S	87.4	Confident	89.1	Confident	88 Å²	88	68 Å²	68	62%	0.615	38%	0.375	S	S	*	.	H	α-helix	trans	-55.8	-18.4	177.8	62.1	0	0	0	0	115	S252	S252-S254 PolarHBondContact O-N 3.43Å; S252-S254 VanDerWaalsContact O-N 3.11Å; S252-S254 PolarHBondContact OG-OG 3.03Å
255	C	86.8	Confident	89.4	Confident	35 Å²	35	66.5 Å²	66.5	24%	0.236	37%	0.365	C	S	.	.	H	α-helix	trans	-88.4	-26.9	-177.5	-73.9	0	0	0	0	113.9	I251 S252 A253 C511	I251-C255 HydrophobicContact CG2-CB 3.7Å; S252-C255 VanDerWaalsContact O-CB 3.29Å; S252-C255 WeakPolarHBondContact O-CB 3.4Å; S252-C255 PolarHBondContact O-N 3.05Å; A253-C255 PolarHBondContact O-N 2.76Å; C255-C511 HydrophobicContact CB-CB 3.68Å; C255-C511 WeakPolarHBondContact CB-SG 3.46Å; C255-C511 VanDerWaalsContact SG-CA 3.57Å; C255-C511 WeakPolarHBondContact SG-CB 3.49Å; C255-C511 CovalentContact SG-SG 2.02Å; C255-C511 PolarHBondContact SG-SG 3.27Å
256	Y	89.3	Confident	89.7	Confident	43 Å²	43	63.2 Å²	63.2	17%	0.169	35%	0.349	C	S	.	.	H	α-helix	trans	-117	-14.5	-176.2	59.9	-106.4	0	0	0	113.3	I240 V244 I251 A253 R336 V346	I240-Y256 HydrophobicContact CG2-CD2 3.77Å; I240-Y256 HydrophobicContact CG2-CE2 4.1Å; V244-Y256 HydrophobicContact CB-CD1 4.02Å; V244-Y256 HydrophobicContact CB-CE1 3.8Å; V244-Y256 HydrophobicContact CB-CG 4.46Å; V244-Y256 HydrophobicContact CG1-CD1 3.77Å; V244-Y256 HydrophobicContact CG1-CD2 3.81Å; V244-Y256 HydrophobicContact CG1-CE1 3.88Å; V244-Y256 HydrophobicContact CG1-CE2 3.93Å; V244-Y256 HydrophobicContact CG1-CG 3.71Å; I251-Y256 HydrophobicContact CG2-CD1 4.41Å; A253-Y256 VanDerWaalsContact CA-CE1 3.44Å; A253-Y256 VanDerWaalsContact CA-CZ 3.46Å; A253-Y256 HydrophobicContact CB-CE1 4.38Å; A253-Y256 HydrophobicContact CB-CE2 4.42Å; A253-Y256 PolarHBondContact O-N 2.85Å; A253-Y256 VanDerWaalsContact O-N 3.13Å; Y256-R336 PolarHBondContact O-NH2 3.03Å; Y256-V346 HydrophobicContact CD1-CG2 4.25Å
257	T	92.8	Very high	90.3	Very high	50 Å²	50	62.1 Å²	62.1	31%	0.307	34%	0.337	S	S	.	.	S	Bend	trans	-86.4	133.2	172.4	59.5	0	0	0	0	110.7	I240 A253	I240-T257 HydrophobicContact CD1-CG2 4.05Å; I240-T257 HydrophobicContact CG1-CG2 4.37Å; A253-T257 WeakPolarHBondContact O-CG2 3.3Å; A253-T257 PolarHBondContact O-N 3.35Å; A253-T257 PolarHBondContact O-OG1 3.21Å
258	P	94.8	Very high	90.8	Very high	10 Å²	10	61.9 Å²	61.9	7%	0.065	34%	0.336	C	S	.	.	P	Polyproline II helix	trans	-53.8	145	167	-21.4	31.2	0	0	0	111.4	Y236 M237	Y236-P258 HydrophobicContact CD1-CB 4.19Å; Y236-P258 HydrophobicContact CE1-CB 3.76Å; Y236-P258 HydrophobicContact CE1-CG 4.47Å; Y236-P258 WeakPolarHBondContact O-CG 3.28Å; M237-P258 HydrophobicContact CE-CB 4.42Å; M237-P258 HydrophobicContact SD-CB 4.11Å
259	R	92.8	Very high	91.3	Very high	73 Å²	73	55.6 Å²	55.6	28%	0.275	31%	0.305	S	S	.	.	P	Polyproline II helix	trans	-72.9	147.4	178.9	-60.6	178.6	61.4	126.9	5.5	111	M237 D261 S262 D273	M237-R259 WeakPolarHBondContact CE-O 3.38Å; R259-D261 WeakPolarHBondContact CB-OD1 3.42Å; R259-D261 IonicContact CZ-OD1 3.36Å; R259-D261 IonicContact NE-OD1 3.27Å; R259-D261 PolarHBondContact NE-OD1 2.93Å; R259-D261 IonicContact NE-OD2 3.09Å; R259-D261 IonicContact NH2-OD1 2.8Å; R259-D261 IonicContact NH2-OD2 2.65Å; R259-D261 PolarHBondContact NH2-OD2 3.25Å; R259-D261 PolarHBondContact O-N 2.84Å; R259-S262 PolarHBondContact N-OG 2.87Å; R259-S262 VanDerWaalsContact O-CB 3.25Å; R259-S262 WeakPolarHBondContact O-CB 3.26Å; R259-S262 PolarHBondContact O-N 3.04Å; R259-S262 VanDerWaalsContact O-N 3.1Å; R259-S262 PolarHBondContact O-OG 2.84Å; R259-D273 IonicContact CZ-OD1 3.06Å; R259-D273 IonicContact NH1-OD1 3.01Å; R259-D273 PolarHBondContact NH1-OD1 3.47Å
260	E	93.3	Very high	91.6	Very high	186 Å²	186	57.9 Å²	57.9	87%	0.869	32%	0.322	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.4	-32.4	175.6	-63.1	-176.1	174.1	0	0	112.5	S262	E260-S262 VanDerWaalsContact C-N 3.3Å; E260-S262 PolarHBondContact O-N 2.84Å
261	D	94.4	Very high	91.8	Very high	34 Å²	34	57.1 Å²	57.1	18%	0.182	32%	0.317	C	S	.	.	T	Hydrogen-bonded Turn	trans	-89.6	20.5	177.3	63.9	-13.4	0	0	0	113.5	R259 F263 H264 R267	R259-D261 WeakPolarHBondContact CB-OD1 3.42Å; R259-D261 IonicContact CZ-OD1 3.36Å; R259-D261 IonicContact NE-OD1 3.27Å; R259-D261 PolarHBondContact NE-OD1 2.93Å; R259-D261 IonicContact NE-OD2 3.09Å; R259-D261 IonicContact NH2-OD1 2.8Å; R259-D261 IonicContact NH2-OD2 2.65Å; R259-D261 PolarHBondContact NH2-OD2 3.25Å; R259-D261 PolarHBondContact O-N 2.84Å; D261-F263 PolarHBondContact O-N 3.45Å; D261-F263 VanDerWaalsContact O-N 3.1Å; D261-H264 PolarHBondContact O-N 3.41Å; D261-R267 WeakPolarHBondContact OD2-CG 3.3Å; D261-R267 IonicContact OD2-NE 2.77Å
262	S	95.3	Very high	92	Very high	0 Å²	0	56.7 Å²	56.7	0%	0	32%	0.317	C	S	.	.	T	Hydrogen-bonded Turn	trans	-60.1	-23.9	-177.9	-68.6	0	0	0	0	114.2	G95 V96 R259 E260	G95-S262 CarbonylContact C-O 3.48Å; G95-S262 WeakPolarHBondContact CA-O 3.34Å; V96-S262 WeakPolarHBondContact CG2-O 3.09Å; V96-S262 PolarHBondContact N-O 2.92Å; R259-S262 PolarHBondContact N-OG 2.87Å; R259-S262 VanDerWaalsContact O-CB 3.25Å; R259-S262 WeakPolarHBondContact O-CB 3.26Å; R259-S262 PolarHBondContact O-N 3.04Å; R259-S262 VanDerWaalsContact O-N 3.1Å; R259-S262 PolarHBondContact O-OG 2.84Å; E260-S262 VanDerWaalsContact C-N 3.3Å; E260-S262 PolarHBondContact O-N 2.84Å
263	F	95.9	Very high	92	Very high	39 Å²	39	55.1 Å²	55.1	17%	0.171	30%	0.303	C	S	.	.	T	Hydrogen-bonded Turn	trans	-102.2	6.8	179.4	-66	-78.1	0	0	0	114.1	V96 F232 T233 Y236 M237 D261 M333	V96-F263 HydrophobicContact CG1-CD1 4Å; V96-F263 HydrophobicContact CG1-CE1 4.46Å; V96-F263 VanDerWaalsContact CG2-C 3.44Å; V96-F263 WeakPolarHBondContact CG2-O 3.46Å; F232-F263 HydrophobicContact CD1-CE1 4.44Å; F232-F263 AromaticContact CE1-CE1 3.63Å; F232-F263 HydrophobicContact CE1-CE1 3.63Å; F232-F263 HydrophobicContact CE1-CZ 4.2Å; F232-F263 AromaticContact CZ-CE1 3.96Å; F232-F263 HydrophobicContact CZ-CE1 3.96Å; F232-F263 HydrophobicContact CZ-CZ 4.33Å; T233-F263 HydrophobicContact CG2-CD1 4.18Å; T233-F263 HydrophobicContact CG2-CE1 3.74Å; T233-F263 HydrophobicContact CG2-CE2 4.35Å; T233-F263 HydrophobicContact CG2-CZ 3.85Å; Y236-F263 AromaticContact CD1-CE2 3.91Å; Y236-F263 HydrophobicContact CD1-CE2 3.91Å; Y236-F263 AromaticContact CD1-CZ 3.88Å; Y236-F263 HydrophobicContact CD1-CZ 3.88Å; Y236-F263 HydrophobicContact CG-CZ 4.18Å; M237-F263 HydrophobicContact CG-CE2 4.26Å; M237-F263 HydrophobicContact SD-CE2 4.16Å; D261-F263 PolarHBondContact O-N 3.45Å; D261-F263 VanDerWaalsContact O-N 3.1Å; F263-M333 HydrophobicContact CD1-CE 4.15Å; F263-M333 HydrophobicContact CE1-CE 3.37Å; F263-M333 HydrophobicContact CE2-CE 4.34Å; F263-M333 HydrophobicContact CZ-CE 3.48Å; F263-M333 VanDerWaalsContact CZ-CE 3.48Å
264	H	95.3	Very high	92.2	Very high	94 Å²	94	52.9 Å²	52.9	44%	0.435	28%	0.284	S	S	.	.			trans	-111.4	135.8	176.9	-60.6	90.3	0	0	0	110.3	D261 Y658	D261-H264 PolarHBondContact O-N 3.41Å; H264-Y658 CarbonylContact C-O 3.58Å; H264-Y658 WeakPolarHBondContact CA-O 3.47Å
265	I	94.9	Very high	92.6	Very high	0 Å²	0	48.7 Å²	48.7	0%	0	26%	0.255	C	S	.	.	S	Bend	trans	-85.1	-26.2	176.5	69.9	-179.1	0	0	0	111.8	V96 V99 T100 W103 R267 I279 Y655 Y658	V96-I265 HydrophobicContact CG2-CG2 4.15Å; V99-I265 HydrophobicContact CG1-CG2 4.18Å; T100-I265 HydrophobicContact CG2-CB 3.9Å; T100-I265 HydrophobicContact CG2-CD1 4.49Å; T100-I265 HydrophobicContact CG2-CG2 4.3Å; W103-I265 HydrophobicContact CZ3-CD1 4.39Å; I265-R267 PolarHBondContact O-N 2.85Å; I265-I279 WeakPolarHBondContact O-CD1 3.42Å; I265-Y655 HydrophobicContact CD1-CD1 3.49Å; I265-Y655 VanDerWaalsContact CD1-CD1 3.49Å; I265-Y655 HydrophobicContact CD1-CE1 4.04Å; I265-Y655 HydrophobicContact CD1-CG 3.98Å; I265-Y658 WeakPolarHBondContact CG1-O 3.44Å; I265-Y658 PolarHBondContact N-O 3.08Å
266	F	94.8	Very high	92.9	Very high	66 Å²	66	52 Å²	52	29%	0.289	26%	0.262	S	S	.	.	S	Bend	trans	-95	94.6	174.8	-61.5	-28.1	0	0	0	111.2	W276 I279 I280 Y655 A659	F266-W276 HydrophobicContact CB-CB 3.58Å; F266-W276 HydrophobicContact CB-CG 4.29Å; F266-W276 HydrophobicContact CD1-CB 3.76Å; F266-W276 HydrophobicContact CG-CB 3.88Å; F266-I279 HydrophobicContact CE1-CG2 4.45Å; F266-I280 HydrophobicContact CE1-CD1 3.99Å; F266-I280 HydrophobicContact CE1-CG1 4.34Å; F266-I280 HydrophobicContact CZ-CD1 3.97Å; F266-Y655 HydrophobicContact CE1-CD1 4.04Å; F266-Y655 HydrophobicContact CE1-CE1 4.39Å; F266-Y655 AromaticContact CZ-CD1 3.96Å; F266-Y655 HydrophobicContact CZ-CD1 3.96Å; F266-A659 VanDerWaalsContact CB-OXT 3.28Å; F266-A659 WeakPolarHBondContact CB-OXT 3.47Å; F266-A659 HydrophobicContact CD2-CB 3.59Å; F266-A659 HydrophobicContact CE2-CB 3.75Å; F266-A659 PolarHBondContact N-OXT 3.13Å
267	R	94.3	Very high	93.2	Very high	2 Å²	2	50.9 Å²	50.9	1%	0.008	26%	0.26	C	S	.	.	B	Isolated β-bridge	trans	-87.3	163.1	177.1	-56.8	-170.9	169.1	160.9	2.5	112.1	S94 A97 D261 I265 D273 I274 W276	S94-R267 PolarHBondContact O-NH2 3.41Å; A97-R267 HydrophobicContact CB-CG 4.39Å; A97-R267 VanDerWaalsContact CB-NH2 3.28Å; D261-R267 WeakPolarHBondContact OD2-CG 3.3Å; D261-R267 IonicContact OD2-NE 2.77Å; I265-R267 PolarHBondContact O-N 2.85Å; R267-D273 WeakPolarHBondContact CD-OD1 3.46Å; R267-D273 IonicContact CZ-OD1 3.82Å; R267-D273 IonicContact NE-OD1 3.17Å; R267-D273 IonicContact NH1-OD1 3.91Å; R267-D273 PolarHBondContact NH1-OD1 3.01Å; R267-D273 IonicContact NH1-OD2 3.12Å; R267-D273 PolarHBondContact NH1-OD2 3.34Å; R267-I274 WeakPolarHBondContact CB-O 3.31Å; R267-W276 PolarHBondContact O-N 3.3Å
268	D	94.5	Very high	93.3	Very high	73 Å²	73	48.5 Å²	48.5	39%	0.39	25%	0.246	S	C	.	.			trans	-45.7	133.1	178.3	-178.3	-93.8	0	0	0	112	V270 T271 G272	D268-V270 PolarHBondContact O-N 3Å; D268-V270 VanDerWaalsContact O-N 3.14Å; D268-V270 PolarHBondContact OD1-N 3.12Å; D268-T271 WeakPolarHBondContact CB-OG1 3.38Å; D268-T271 PolarHBondContact OD1-N 3.27Å; D268-T271 PolarHBondContact OD1-OG1 2.89Å; D268-G272 WeakPolarHBondContact O-CA 3.38Å; D268-G272 PolarHBondContact O-N 3.22Å
269	P	93.9	Very high	93.3	Very high	46 Å²	46	48.1 Å²	48.1	30%	0.299	24%	0.243	S	C	.	.	T	Hydrogen-bonded Turn	trans	-66.1	-15.7	-173.5	25.5	-36	0	0	0	114.5	P277 Y528	P269-P277 HydrophobicContact CB-CG 3.75Å; P269-Y528 WeakPolarHBondContact O-CE2 3.47Å; P269-Y528 PolarHBondContact O-OH 3.01Å
270	V	88.8	Confident	93.4	Very high	126 Å²	126	47.9 Å²	47.9	76%	0.764	25%	0.246	S	C	*	.	T	Hydrogen-bonded Turn	trans	-118	-41.7	-175	-177.7	0	0	0	0	111.8	D268	D268-V270 PolarHBondContact O-N 3Å; D268-V270 VanDerWaalsContact O-N 3.14Å; D268-V270 PolarHBondContact OD1-N 3.12Å
271	T	87.2	Confident	93.5	Very high	102 Å²	102	44.7 Å²	44.7	63%	0.626	23%	0.23	S	C	*	.	T	Hydrogen-bonded Turn	trans	-104.2	-7.3	-173.9	62	0	0	0	0	113.3	D268	D268-T271 WeakPolarHBondContact CB-OG1 3.38Å; D268-T271 PolarHBondContact OD1-N 3.27Å; D268-T271 PolarHBondContact OD1-OG1 2.89Å
272	G	88.7	Confident	93.6	Very high	6 Å²	6	43.1 Å²	43.1	6%	0.062	22%	0.221	C	C	.	.			trans	-64.3	137.2	169.8	0	0	0	0	0	111.4	D268 I274	D268-G272 WeakPolarHBondContact O-CA 3.38Å; D268-G272 PolarHBondContact O-N 3.22Å; G272-I274 VanDerWaalsContact C-N 3.26Å
273	D	88.8	Confident	93.6	Very high	37 Å²	37	43.2 Å²	43.2	20%	0.198	22%	0.222	C	C	.	.	S	Bend	trans	-69.1	-26.2	168.1	59.9	-27.7	0	0	0	112.3	S94 R259 R267 H525	S94-D273 VanDerWaalsContact CB-OD2 3.31Å; S94-D273 WeakPolarHBondContact CB-OD2 3.08Å; R259-D273 IonicContact CZ-OD1 3.06Å; R259-D273 IonicContact NH1-OD1 3.01Å; R259-D273 PolarHBondContact NH1-OD1 3.47Å; R267-D273 WeakPolarHBondContact CD-OD1 3.46Å; R267-D273 IonicContact CZ-OD1 3.82Å; R267-D273 IonicContact NE-OD1 3.17Å; R267-D273 IonicContact NH1-OD1 3.91Å; R267-D273 PolarHBondContact NH1-OD1 3.01Å; R267-D273 IonicContact NH1-OD2 3.12Å; R267-D273 PolarHBondContact NH1-OD2 3.34Å; D273-H525 PolarHBondContact O-NE2 3.25Å
274	I	92.7	Very high	93.6	Very high	0 Å²	0	43 Å²	43	0%	0	23%	0.225	C	C	.	.	S	Bend	trans	-129.3	82.7	168.9	-49.1	178.3	0	0	0	107.9	A97 F101 R267 G272 I279 L527	A97-I274 HydrophobicContact CB-CB 4.5Å; A97-I274 HydrophobicContact CB-CD1 4.11Å; F101-I274 HydrophobicContact CE2-CD1 3.78Å; F101-I274 HydrophobicContact CZ-CD1 4.09Å; F101-I274 HydrophobicContact CZ-CG1 4.47Å; F101-I274 HydrophobicContact CZ-CG2 4.44Å; R267-I274 WeakPolarHBondContact CB-O 3.31Å; G272-I274 VanDerWaalsContact C-N 3.26Å; I274-I279 HydrophobicContact CB-CD1 4.41Å; I274-I279 HydrophobicContact CG2-CD1 3.54Å; I274-I279 HydrophobicContact CG2-CG1 3.57Å; I274-L527 HydrophobicContact CG2-CD1 4.31Å
275	P	94.8	Very high	93.7	Very high	1 Å²	1	39.2 Å²	39.2	1%	0.006	21%	0.208	C	C	.	.	B	Isolated β-bridge	trans	-69.7	135.8	-171.4	28.1	-35	0	0	0	111.4	P277 G278 I279 H525 Y528	P275-P277 VanDerWaalsContact C-CD 3.43Å; P275-G278 VanDerWaalsContact O-CA 3.31Å; P275-G278 WeakPolarHBondContact O-CA 3.36Å; P275-G278 PolarHBondContact O-N 3.37Å; P275-I279 PolarHBondContact O-N 3.07Å; P275-I279 VanDerWaalsContact O-N 3.07Å; P275-H525 HydrophobicContact CG-CB 4.35Å; P275-Y528 HydrophobicContact CB-CE2 4.24Å; P275-Y528 WeakPolarHBondContact CB-OH 3.5Å; P275-Y528 HydrophobicContact CG-CE2 3.97Å
276	W	94.8	Very high	93.7	Very high	104 Å²	104	39.5 Å²	39.5	39%	0.394	21%	0.209	S	C	.	.	H	α-helix	trans	-56.8	-38.8	-173.5	80.8	-101.5	0	0	0	115.3	F266 R267 G278 I279 I280 F281	F266-W276 HydrophobicContact CB-CB 3.58Å; F266-W276 HydrophobicContact CB-CG 4.29Å; F266-W276 HydrophobicContact CD1-CB 3.76Å; F266-W276 HydrophobicContact CG-CB 3.88Å; R267-W276 PolarHBondContact O-N 3.3Å; W276-G278 PolarHBondContact O-N 3.32Å; W276-I279 WeakPolarHBondContact O-CB 3.15Å; W276-I279 PolarHBondContact O-N 3.19Å; W276-I279 VanDerWaalsContact O-N 3.13Å; W276-I280 HydrophobicContact CE3-CG1 4.02Å; W276-I280 HydrophobicContact CZ3-CG1 4.36Å; W276-I280 WeakPolarHBondContact O-CG1 3.08Å; W276-I280 PolarHBondContact O-N 2.99Å; W276-F281 HydrophobicContact CZ3-CE2 4.5Å
277	P	95.6	Very high	93.8	Very high	19 Å²	19	36.8 Å²	36.8	12%	0.123	20%	0.199	C	C	.	.	H	α-helix	trans	-71.9	-26.7	177.6	-2.6	18	0	0	0	110.9	P269 P275 I279 I280 F281 Y528	P269-P277 HydrophobicContact CB-CG 3.75Å; P275-P277 VanDerWaalsContact C-CD 3.43Å; P277-I279 VanDerWaalsContact C-N 3.34Å; P277-I280 PolarHBondContact O-N 2.63Å; P277-F281 HydrophobicContact CB-CD2 4.2Å; P277-F281 HydrophobicContact CB-CE2 4.48Å; P277-F281 WeakPolarHBondContact O-CB 3.26Å; P277-F281 VanDerWaalsContact O-CD2 3.31Å; P277-F281 WeakPolarHBondContact O-CD2 2.94Å; P277-F281 PolarHBondContact O-N 2.69Å; P277-Y528 HydrophobicContact CB-CE1 3.94Å; P277-Y528 VanDerWaalsContact CD-OH 3.25Å; P277-Y528 WeakPolarHBondContact CD-OH 3.38Å; P277-Y528 HydrophobicContact CG-CE1 4.22Å; P277-Y528 VanDerWaalsContact CG-OH 3.27Å; P277-Y528 WeakPolarHBondContact CG-OH 3.42Å
278	G	94.9	Very high	93.9	Very high	0 Å²	0	37.7 Å²	37.7	0%	0	20%	0.204	C	C	.	.	I	π-helix	trans	-61.7	-42.9	168.6	0	0	0	0	0	111.7	P275 W276 G282 M283	P275-G278 VanDerWaalsContact O-CA 3.31Å; P275-G278 WeakPolarHBondContact O-CA 3.36Å; P275-G278 PolarHBondContact O-N 3.37Å; W276-G278 PolarHBondContact O-N 3.32Å; G278-G282 CarbonylContact O-C 3.13Å; G278-G282 VanDerWaalsContact O-CA 3.27Å; G278-G282 WeakPolarHBondContact O-CA 3.01Å; G278-G282 PolarHBondContact O-N 2.81Å; G278-M283 PolarHBondContact O-N 3.1Å
279	I	94.3	Very high	94	Very high	2 Å²	2	34.8 Å²	34.8	1%	0.01	19%	0.187	C	C	.	.	I	π-helix	trans	-64.1	-42.6	175.2	-67.2	160.5	0	0	0	111.6	T100 I265 F266 I274 P275 W276 P277 M283 P284 Y655	T100-I279 HydrophobicContact CG2-CD1 3.96Å; T100-I279 HydrophobicContact CG2-CG1 4.35Å; T100-I279 HydrophobicContact CG2-CG2 3.94Å; I265-I279 WeakPolarHBondContact O-CD1 3.42Å; F266-I279 HydrophobicContact CE1-CG2 4.45Å; I274-I279 HydrophobicContact CB-CD1 4.41Å; I274-I279 HydrophobicContact CG2-CD1 3.54Å; I274-I279 HydrophobicContact CG2-CG1 3.57Å; P275-I279 PolarHBondContact O-N 3.07Å; P275-I279 VanDerWaalsContact O-N 3.07Å; W276-I279 WeakPolarHBondContact O-CB 3.15Å; W276-I279 PolarHBondContact O-N 3.19Å; W276-I279 VanDerWaalsContact O-N 3.13Å; P277-I279 VanDerWaalsContact C-N 3.34Å; I279-M283 HydrophobicContact CB-SD 4.29Å; I279-M283 HydrophobicContact CG1-SD 4.31Å; I279-M283 HydrophobicContact CG2-SD 3.94Å; I279-M283 WeakPolarHBondContact O-CB 3.44Å; I279-P284 VanDerWaalsContact O-CD 3.32Å; I279-P284 WeakPolarHBondContact O-CD 3.16Å; I279-Y655 HydrophobicContact CG2-CE1 4.22Å
280	I	94.8	Very high	94	Very high	68 Å²	68	34 Å²	34	35%	0.349	18%	0.179	S	C	.	.	I	π-helix	trans	-77.9	-34.3	-175.2	-65.3	-61.3	0	0	0	112.7	F266 W276 P277 P284	F266-I280 HydrophobicContact CE1-CD1 3.99Å; F266-I280 HydrophobicContact CE1-CG1 4.34Å; F266-I280 HydrophobicContact CZ-CD1 3.97Å; W276-I280 HydrophobicContact CE3-CG1 4.02Å; W276-I280 HydrophobicContact CZ3-CG1 4.36Å; W276-I280 WeakPolarHBondContact O-CG1 3.08Å; W276-I280 PolarHBondContact O-N 2.99Å; P277-I280 PolarHBondContact O-N 2.63Å; I280-P284 VanDerWaalsContact O-CG 3.28Å; I280-P284 WeakPolarHBondContact O-CG 3.46Å
281	F	95.5	Very high	94.4	Very high	120 Å²	120	28.1 Å²	28.1	53%	0.526	14%	0.143	S	C	.	.	I	π-helix	trans	-115.2	-38.8	-171.6	-58.9	-68.8	0	0	0	113.9	W276 P277 I285 I531	W276-F281 HydrophobicContact CZ3-CE2 4.5Å; P277-F281 HydrophobicContact CB-CD2 4.2Å; P277-F281 HydrophobicContact CB-CE2 4.48Å; P277-F281 WeakPolarHBondContact O-CB 3.26Å; P277-F281 VanDerWaalsContact O-CD2 3.31Å; P277-F281 WeakPolarHBondContact O-CD2 2.94Å; P277-F281 PolarHBondContact O-N 2.69Å; F281-I285 VanDerWaalsContact O-CD1 3.26Å; F281-I285 WeakPolarHBondContact O-CD1 3.39Å; F281-I285 WeakPolarHBondContact O-CG1 3.39Å; F281-I531 HydrophobicContact CB-CD1 3.55Å; F281-I531 HydrophobicContact CB-CG1 4.12Å
282	G	95.8	Very high	94.8	Very high	0 Å²	0	23.3 Å²	23.3	0%	0	11%	0.113	C	C	.	.	I	π-helix	trans	-83	-38	-175.9	0	0	0	0	0	113.8	G278 I285 T286 L527 S530 I531	G278-G282 CarbonylContact O-C 3.13Å; G278-G282 VanDerWaalsContact O-CA 3.27Å; G278-G282 WeakPolarHBondContact O-CA 3.01Å; G278-G282 PolarHBondContact O-N 2.81Å; G282-I285 WeakPolarHBondContact O-CB 3.47Å; G282-I285 PolarHBondContact O-N 3.48Å; G282-T286 PolarHBondContact O-N 2.79Å; G282-L527 WeakPolarHBondContact CA-O 3.42Å; G282-S530 PolarHBondContact O-OG 3.42Å; G282-I531 VanDerWaalsContact CA-CG1 3.42Å
283	M	94.8	Very high	95.1	Very high	3 Å²	3	23.3 Å²	23.3	2%	0.015	11%	0.112	C	C	.	.	H	α-helix	trans	-73.7	-37	-176.8	177.7	178.7	-121.6	0	0	114	T100 F101 T104 G278 I279 I285 T286 A287 L527	T100-M283 WeakPolarHBondContact O-CE 3.42Å; F101-M283 HydrophobicContact CB-CE 4.02Å; F101-M283 HydrophobicContact CD1-CE 2.92Å; F101-M283 HydrophobicContact CE1-CE 3.35Å; F101-M283 HydrophobicContact CG-CE 3.62Å; F101-M283 HydrophobicContact CZ-CE 4.35Å; T104-M283 HydrophobicContact CG2-CG 4.03Å; T104-M283 WeakPolarHBondContact OG1-CG 3.43Å; T104-M283 PolarHBondContact OG1-SD 2.99Å; G278-M283 PolarHBondContact O-N 3.1Å; I279-M283 HydrophobicContact CB-SD 4.29Å; I279-M283 HydrophobicContact CG1-SD 4.31Å; I279-M283 HydrophobicContact CG2-SD 3.94Å; I279-M283 WeakPolarHBondContact O-CB 3.44Å; M283-I285 PolarHBondContact O-N 3.22Å; M283-T286 PolarHBondContact O-N 2.76Å; M283-T286 PolarHBondContact O-OG1 2.81Å; M283-A287 VanDerWaalsContact O-CB 3.27Å; M283-A287 WeakPolarHBondContact O-CB 3.34Å; M283-A287 PolarHBondContact O-N 3.38Å; M283-L527 HydrophobicContact CB-CD2 4.21Å
284	P	96.7	Very high	95.3	Very high	35 Å²	35	22.3 Å²	22.3	23%	0.227	11%	0.107	C	C	.	.	H	α-helix	trans	-57.6	-30.2	168.9	-31.1	39.4	0	0	0	113.2	T104 M108 I279 I280 L288	T104-P284 HydrophobicContact CG2-CB 4.41Å; T104-P284 HydrophobicContact CG2-CG 4.08Å; M108-P284 HydrophobicContact CE-CB 3.91Å; I279-P284 VanDerWaalsContact O-CD 3.32Å; I279-P284 WeakPolarHBondContact O-CD 3.16Å; I280-P284 VanDerWaalsContact O-CG 3.28Å; I280-P284 WeakPolarHBondContact O-CG 3.46Å; P284-L288 WeakPolarHBondContact O-CB 3.3Å; P284-L288 PolarHBondContact O-N 2.92Å
285	I	97.6	Very high	95.1	Very high	14 Å²	14	22.8 Å²	22.8	7%	0.072	11%	0.109	C	C	.	.	H	α-helix	trans	-69.4	-46.7	178.3	-65.7	163.3	0	0	0	110.7	F281 G282 M283 L288 W289 P465 A468 I531 F534	F281-I285 VanDerWaalsContact O-CD1 3.26Å; F281-I285 WeakPolarHBondContact O-CD1 3.39Å; F281-I285 WeakPolarHBondContact O-CG1 3.39Å; G282-I285 WeakPolarHBondContact O-CB 3.47Å; G282-I285 PolarHBondContact O-N 3.48Å; M283-I285 PolarHBondContact O-N 3.22Å; I285-L288 WeakPolarHBondContact O-CB 3.41Å; I285-L288 PolarHBondContact O-N 2.92Å; I285-W289 PolarHBondContact O-N 3.37Å; I285-W289 VanDerWaalsContact O-N 3.07Å; I285-P465 HydrophobicContact CG2-CB 3.79Å; I285-P465 HydrophobicContact CG2-CG 4.04Å; I285-A468 HydrophobicContact CG2-CB 4.36Å; I285-I531 HydrophobicContact CD1-CG1 4.24Å; I285-F534 HydrophobicContact CB-CD2 4.49Å; I285-F534 HydrophobicContact CD1-CB 3.73Å; I285-F534 HydrophobicContact CD1-CD1 3.92Å; I285-F534 HydrophobicContact CD1-CD2 4.47Å; I285-F534 HydrophobicContact CD1-CG 3.81Å; I285-F534 HydrophobicContact CG1-CB 4.37Å; I285-F534 HydrophobicContact CG1-CD1 4.24Å; I285-F534 HydrophobicContact CG1-CD2 4.24Å; I285-F534 HydrophobicContact CG1-CG 4.04Å; I285-F534 HydrophobicContact CG2-CB 3.87Å; I285-F534 HydrophobicContact CG2-CD2 3.54Å; I285-F534 HydrophobicContact CG2-CE2 4.28Å; I285-F534 HydrophobicContact CG2-CG 3.86Å
286	T	95.5	Very high	94.9	Very high	6 Å²	6	22.8 Å²	22.8	4%	0.037	11%	0.109	C	C	.	.	H	α-helix	trans	-66.9	-41.5	177.4	57.4	0	0	0	0	110.9	G282 M283 L288 W289 Y290 S461	G282-T286 PolarHBondContact O-N 2.79Å; M283-T286 PolarHBondContact O-N 2.76Å; M283-T286 PolarHBondContact O-OG1 2.81Å; T286-L288 VanDerWaalsContact C-N 3.32Å; T286-L288 PolarHBondContact O-N 2.84Å; T286-W289 WeakPolarHBondContact O-CB 3.42Å; T286-W289 PolarHBondContact O-N 3.44Å; T286-Y290 PolarHBondContact O-N 3.17Å; T286-S461 WeakPolarHBondContact CG2-OG 3.37Å
287	A	96.2	Very high	94.8	Very high	9 Å²	9	17.9 Å²	17.9	7%	0.074	9%	0.09	C	C	.	.	H	α-helix	trans	-64.2	-36	174.8	0	0	0	0	0	112	T104 M108 M283 Y290 W291	T104-A287 HydrophobicContact CG2-CB 3.75Å; M108-A287 HydrophobicContact CB-CB 4.47Å; M108-A287 HydrophobicContact CG-CB 3.59Å; M283-A287 VanDerWaalsContact O-CB 3.27Å; M283-A287 WeakPolarHBondContact O-CB 3.34Å; M283-A287 PolarHBondContact O-N 3.38Å; A287-Y290 PolarHBondContact O-N 3.28Å; A287-W291 WeakPolarHBondContact O-CB 3.38Å; A287-W291 PolarHBondContact O-N 3.06Å
288	L	97.1	Very high	94.7	Very high	20 Å²	20	17 Å²	17	11%	0.105	8%	0.084	C	C	.	.	H	α-helix	trans	-63.3	-45.7	174.4	-172	77.2	0	0	0	111.1	M108 I111 F116 P284 I285 T286 C292 A468 V472	M108-L288 HydrophobicContact SD-CB 4.2Å; M108-L288 HydrophobicContact SD-CD1 3.97Å; I111-L288 HydrophobicContact CG2-CD1 4.27Å; F116-L288 HydrophobicContact CE2-CD1 3.86Å; F116-L288 HydrophobicContact CZ-CD1 3.75Å; F116-L288 HydrophobicContact CZ-CG 4.35Å; P284-L288 WeakPolarHBondContact O-CB 3.3Å; P284-L288 PolarHBondContact O-N 2.92Å; I285-L288 WeakPolarHBondContact O-CB 3.41Å; I285-L288 PolarHBondContact O-N 2.92Å; T286-L288 VanDerWaalsContact C-N 3.32Å; T286-L288 PolarHBondContact O-N 2.84Å; L288-C292 HydrophobicContact CD1-CB 4.1Å; L288-C292 HydrophobicContact CG-CB 4.42Å; L288-C292 WeakPolarHBondContact O-CA 3.37Å; L288-C292 WeakPolarHBondContact O-CB 3.42Å; L288-C292 PolarHBondContact O-N 2.86Å; L288-A468 HydrophobicContact CD2-CB 4.23Å; L288-V472 HydrophobicContact CD2-CG2 3.25Å; L288-V472 HydrophobicContact CG-CG2 4.5Å
289	W	95.8	Very high	94.4	Very high	12 Å²	12	17 Å²	17	5%	0.045	9%	0.085	C	C	.	.	I	π-helix	trans	-56.9	-53.3	173.3	165.5	67.4	0	0	0	110.7	I152 L156 I285 T286 T293 N294 A468	I152-W289 HydrophobicContact CD1-CZ2 4.03Å; I152-W289 HydrophobicContact CG2-CH2 3.68Å; I152-W289 HydrophobicContact CG2-CZ2 3.67Å; L156-W289 HydrophobicContact CD2-CH2 3.61Å; L156-W289 HydrophobicContact CD2-CZ3 4.03Å; I285-W289 PolarHBondContact O-N 3.37Å; I285-W289 VanDerWaalsContact O-N 3.07Å; T286-W289 WeakPolarHBondContact O-CB 3.42Å; T286-W289 PolarHBondContact O-N 3.44Å; W289-T293 WeakPolarHBondContact CA-OG1 3.38Å; W289-T293 PolarHBondContact O-N 3.26Å; W289-T293 VanDerWaalsContact O-N 3.1Å; W289-T293 PolarHBondContact O-OG1 3.44Å; W289-N294 PolarHBondContact O-N 3.43Å; W289-N294 VanDerWaalsContact O-N 3.12Å; W289-A468 HydrophobicContact CB-CB 4.03Å
290	Y	94.8	Very high	94.2	Very high	30 Å²	30	17 Å²	17	12%	0.118	8%	0.084	C	C	.	.	I	π-helix	trans	-63.6	-48.4	-176.2	-175.9	-90.8	0	0	0	113.2	N78 L157 T286 A287 N294 I297	N78-Y290 HydrophobicContact CB-CE1 4.03Å; N78-Y290 VanDerWaalsContact CB-OH 3.32Å; N78-Y290 WeakPolarHBondContact CB-OH 3.45Å; N78-Y290 PolarHBondContact ND2-OH 2.99Å; L157-Y290 HydrophobicContact CD2-CE2 4.38Å; T286-Y290 PolarHBondContact O-N 3.17Å; A287-Y290 PolarHBondContact O-N 3.28Å; Y290-N294 WeakPolarHBondContact O-CB 3.37Å; Y290-I297 HydrophobicContact CD1-CG1 4.36Å; Y290-I297 HydrophobicContact CE1-CD1 3.95Å; Y290-I297 HydrophobicContact CE1-CG1 3.85Å
291	W	96.4	Very high	94.1	Very high	3 Å²	3	13.8 Å²	13.8	1%	0.011	7%	0.068	C	C	.	.	I	π-helix	trans	-84.5	-37.1	-174.2	-69.7	101.6	0	0	0	113.2	N78 S105 M108 L109 L112 A287 I297 K321	N78-W291 HydrophobicContact CB-CH2 3.92Å; N78-W291 HydrophobicContact CB-CZ2 4.26Å; N78-W291 VanDerWaalsContact OD1-CZ2 3.26Å; N78-W291 WeakPolarHBondContact OD1-CZ2 3.28Å; S105-W291 VanDerWaalsContact CB-CE2 3.49Å; S105-W291 PolarHBondContact OG-NE1 2.9Å; M108-W291 HydrophobicContact CB-CB 4.11Å; M108-W291 HydrophobicContact CB-CG 4.19Å; L109-W291 HydrophobicContact CD1-CE3 4.4Å; L109-W291 HydrophobicContact CD1-CH2 4.33Å; L109-W291 HydrophobicContact CD1-CZ3 4.21Å; L109-W291 HydrophobicContact CD2-CD2 4.23Å; L109-W291 HydrophobicContact CD2-CE3 3.45Å; L109-W291 VanDerWaalsContact CD2-CE3 3.45Å; L109-W291 HydrophobicContact CD2-CZ3 3.65Å; L109-W291 HydrophobicContact CG-CD2 4.17Å; L109-W291 HydrophobicContact CG-CE3 3.86Å; L109-W291 HydrophobicContact CG-CZ3 4.13Å; L112-W291 WeakPolarHBondContact CD1-O 3.41Å; L112-W291 WeakPolarHBondContact CD2-O 3.42Å; A287-W291 WeakPolarHBondContact O-CB 3.38Å; A287-W291 PolarHBondContact O-N 3.06Å; W291-I297 HydrophobicContact CE3-CG1 4.46Å; W291-I297 HydrophobicContact CE3-CG2 3.67Å; W291-I297 HydrophobicContact CZ3-CD1 4.23Å; W291-I297 HydrophobicContact CZ3-CG2 4.15Å; W291-I297 WeakPolarHBondContact O-CG2 3.27Å; W291-K321 HydrophobicContact CZ2-CD 4.46Å
292	C	96.2	Very high	93.8	Very high	0 Å²	0	8.2 Å²	8.2	0%	0	4%	0.044	C	C	.	.	I	π-helix	trans	-99.1	-18.6	-169.8	-58.5	0	0	0	0	114	F116 Y120 L288 V298	F116-C292 HydrophobicContact CB-CB 4.38Å; F116-C292 HydrophobicContact CD1-CB 3.61Å; F116-C292 HydrophobicContact CD2-CB 3.89Å; F116-C292 HydrophobicContact CE1-CB 3.73Å; F116-C292 HydrophobicContact CE2-CB 4.04Å; F116-C292 HydrophobicContact CG-CB 3.7Å; F116-C292 HydrophobicContact CZ-CB 3.97Å; Y120-C292 WeakPolarHBondContact CE2-O 3.37Å; Y120-C292 PolarHBondContact OH-O 2.94Å; Y120-C292 VanDerWaalsContact OH-O 3.04Å; L288-C292 HydrophobicContact CD1-CB 4.1Å; L288-C292 HydrophobicContact CG-CB 4.42Å; L288-C292 WeakPolarHBondContact O-CA 3.37Å; L288-C292 WeakPolarHBondContact O-CB 3.42Å; L288-C292 PolarHBondContact O-N 2.86Å; C292-V298 WeakPolarHBondContact O-CG2 3.16Å
293	T	94.1	Very high	93.4	Very high	7 Å²	7	8.2 Å²	8.2	4%	0.043	4%	0.044	C	C	.	.	I	π-helix	trans	-125.8	-14.6	-174.3	77.5	0	0	0	0	114.2	M128 W289 Q295 Y471	M128-T293 WeakPolarHBondContact CG-O 3.48Å; W289-T293 WeakPolarHBondContact CA-OG1 3.38Å; W289-T293 PolarHBondContact O-N 3.26Å; W289-T293 VanDerWaalsContact O-N 3.1Å; W289-T293 PolarHBondContact O-OG1 3.44Å; T293-Q295 PolarHBondContact O-N 2.79Å; T293-Y471 HydrophobicContact CG2-CD1 4.06Å; T293-Y471 HydrophobicContact CG2-CD2 3.74Å; T293-Y471 HydrophobicContact CG2-CE2 4.48Å; T293-Y471 HydrophobicContact CG2-CG 3.49Å; T293-Y471 VanDerWaalsContact CG2-CG 3.49Å
294	N	92.3	Very high	93.1	Very high	16 Å²	16	8.2 Å²	8.2	9%	0.086	4%	0.044	C	C	.	.			trans	-72.9	128.2	179.6	-170.3	-24.9	0	0	0	111	W289 Y290 V296 I297 V298	W289-N294 PolarHBondContact O-N 3.43Å; W289-N294 VanDerWaalsContact O-N 3.12Å; Y290-N294 WeakPolarHBondContact O-CB 3.37Å; N294-V296 VanDerWaalsContact C-N 3.26Å; N294-V296 PolarHBondContact O-N 3.49Å; N294-V296 PolarHBondContact OD1-N 2.9Å; N294-I297 HydrophobicContact CB-CG1 4.48Å; N294-I297 PolarHBondContact O-N 3.23Å; N294-V298 WeakPolarHBondContact O-CG2 3.45Å; N294-V298 PolarHBondContact O-N 3.13Å
295	Q	89.9	Confident	92.6	Very high	9 Å²	9	12.4 Å²	12.4	4%	0.042	6%	0.059	C	C	.	.	H	α-helix	trans	-52.9	-42.7	177.6	-175.6	64	22	0	0	112.3	T126 T127 T293 I297 Q299 L404	T126-Q295 PolarHBondContact O-NE2 3.24Å; T126-Q295 VanDerWaalsContact O-NE2 3.14Å; T127-Q295 VanDerWaalsContact CA-OE1 3.31Å; T293-Q295 PolarHBondContact O-N 2.79Å; Q295-I297 VanDerWaalsContact C-N 3.27Å; Q295-I297 PolarHBondContact O-N 2.86Å; Q295-Q299 WeakPolarHBondContact O-CB 2.99Å; Q295-Q299 PolarHBondContact O-N 2.9Å; Q295-L404 HydrophobicContact CB-CD1 4.34Å; Q295-L404 HydrophobicContact CB-CD2 4.33Å; Q295-L404 HydrophobicContact CB-CG 4.46Å; Q295-L404 HydrophobicContact CG-CD2 4.09Å; Q295-L404 HydrophobicContact CG-CG 4.15Å
296	V	89.4	Confident	92.2	Very high	2 Å²	2	14.6 Å²	14.6	1%	0.012	7%	0.071	C	C	.	.	H	α-helix	trans	-58.4	-40.4	-176.2	-178.3	0	0	0	0	111.9	N294 R300 S400	N294-V296 VanDerWaalsContact C-N 3.26Å; N294-V296 PolarHBondContact O-N 3.49Å; N294-V296 PolarHBondContact OD1-N 2.9Å; V296-R300 PolarHBondContact O-NH1 3.42Å; V296-S400 WeakPolarHBondContact CA-OG 3.27Å; V296-S400 WeakPolarHBondContact CG2-OG 3.23Å
297	I	93	Very high	92.1	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-84.6	-52.7	-175.8	-59.5	-54.7	0	0	0	110.3	L74 L112 Y290 W291 N294 Q295 Q299 R300 C301	L74-I297 HydrophobicContact CD2-CG2 3.83Å; L112-I297 HydrophobicContact CD2-CG2 4.04Å; Y290-I297 HydrophobicContact CD1-CG1 4.36Å; Y290-I297 HydrophobicContact CE1-CD1 3.95Å; Y290-I297 HydrophobicContact CE1-CG1 3.85Å; W291-I297 HydrophobicContact CE3-CG1 4.46Å; W291-I297 HydrophobicContact CE3-CG2 3.67Å; W291-I297 HydrophobicContact CZ3-CD1 4.23Å; W291-I297 HydrophobicContact CZ3-CG2 4.15Å; W291-I297 WeakPolarHBondContact O-CG2 3.27Å; N294-I297 HydrophobicContact CB-CG1 4.48Å; N294-I297 PolarHBondContact O-N 3.23Å; Q295-I297 VanDerWaalsContact C-N 3.27Å; Q295-I297 PolarHBondContact O-N 2.86Å; I297-Q299 VanDerWaalsContact C-N 3.3Å; I297-Q299 PolarHBondContact O-N 3.48Å; I297-R300 WeakPolarHBondContact O-CB 3.42Å; I297-R300 PolarHBondContact O-N 2.92Å; I297-R300 VanDerWaalsContact O-N 3.16Å; I297-C301 PolarHBondContact O-N 2.88Å
298	V	93.1	Very high	92	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-64.7	-36.3	-174.1	-178.3	0	0	0	0	111.4	L112 Y120 M128 C292 N294 R300 C301 L302	L112-V298 HydrophobicContact CD1-CG2 4.17Å; Y120-V298 HydrophobicContact CD2-CG1 3.51Å; Y120-V298 HydrophobicContact CE2-CG1 3.82Å; Y120-V298 HydrophobicContact CE2-CG2 4.25Å; Y120-V298 HydrophobicContact CG-CG1 4.44Å; M128-V298 HydrophobicContact CE-CB 3.97Å; M128-V298 HydrophobicContact CE-CG1 3.33Å; M128-V298 HydrophobicContact CG-CB 4.35Å; M128-V298 HydrophobicContact SD-CB 3.84Å; M128-V298 HydrophobicContact SD-CG1 3.57Å; M128-V298 VanDerWaalsContact SD-CG1 3.57Å; M128-V298 HydrophobicContact SD-CG2 4Å; C292-V298 WeakPolarHBondContact O-CG2 3.16Å; N294-V298 WeakPolarHBondContact O-CG2 3.45Å; N294-V298 PolarHBondContact O-N 3.13Å; V298-R300 PolarHBondContact O-N 3.07Å; V298-C301 WeakPolarHBondContact O-CB 3.31Å; V298-C301 PolarHBondContact O-N 3.2Å; V298-L302 HydrophobicContact CG1-CD1 4.39Å; V298-L302 HydrophobicContact CG1-CG 4.3Å; V298-L302 WeakPolarHBondContact O-CG 3.32Å; V298-L302 PolarHBondContact O-N 2.9Å
299	Q	88.5	Confident	91.9	Very high	1 Å²	1	15.9 Å²	15.9	1%	0.005	8%	0.076	C	C	.	.	H	α-helix	trans	-56.9	-34.4	177.9	-176.8	171.2	-0.4	0	0	112.8	F59 L197 Q295 I297 L302 S303	F59-Q299 PolarHBondContact O-NE2 2.94Å; L197-Q299 HydrophobicContact CD2-CG 4.11Å; Q295-Q299 WeakPolarHBondContact O-CB 2.99Å; Q295-Q299 PolarHBondContact O-N 2.9Å; I297-Q299 VanDerWaalsContact C-N 3.3Å; I297-Q299 PolarHBondContact O-N 3.48Å; Q299-L302 PolarHBondContact O-N 2.75Å; Q299-S303 PolarHBondContact O-N 2.75Å
300	R	91.2	Very high	91.9	Very high	2 Å²	2	15.3 Å²	15.3	1%	0.008	7%	0.073	C	C	.	.	H	α-helix	trans	-70.6	-41.7	176	-71.1	172.9	161.7	82.1	-2.3	112.2	S73 L74 S77 L197 D204 V296 I297 V298 L302 S303 S396	S73-R300 PolarHBondContact OG-NE 2.92Å; L74-R300 HydrophobicContact CD2-CB 3.92Å; L74-R300 HydrophobicContact CG-CB 4.43Å; S77-R300 PolarHBondContact OG-NE 3.4Å; S77-R300 PolarHBondContact OG-NH1 2.95Å; S77-R300 PolarHBondContact OG-NH2 2.96Å; L197-R300 HydrophobicContact CD1-CG 4.49Å; D204-R300 IonicContact OD2-NH2 3.52Å; D204-R300 PolarHBondContact OD2-NH2 3.32Å; V296-R300 PolarHBondContact O-NH1 3.42Å; I297-R300 WeakPolarHBondContact O-CB 3.42Å; I297-R300 PolarHBondContact O-N 2.92Å; I297-R300 VanDerWaalsContact O-N 3.16Å; V298-R300 PolarHBondContact O-N 3.07Å; R300-L302 PolarHBondContact O-N 3.06Å; R300-S303 WeakPolarHBondContact O-CB 3.28Å; R300-S303 PolarHBondContact O-N 3.14Å; R300-S303 PolarHBondContact O-OG 2.56Å; R300-S396 PolarHBondContact NH2-OG 3.2Å
301	C	92.8	Very high	92.1	Very high	0 Å²	0	14.6 Å²	14.6	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-61.6	-33.8	173.9	-66.7	0	0	0	0	111.9	V117 I297 V298 S303 G304 V310	V117-C301 HydrophobicContact CG1-CB 4.37Å; V117-C301 HydrophobicContact CG2-CB 3.64Å; I297-C301 PolarHBondContact O-N 2.88Å; V298-C301 WeakPolarHBondContact O-CB 3.31Å; V298-C301 PolarHBondContact O-N 3.2Å; C301-S303 PolarHBondContact O-N 3.11Å; C301-G304 PolarHBondContact O-N 3.4Å; C301-V310 HydrophobicContact CB-CG1 3.85Å; C301-V310 WeakPolarHBondContact O-CG2 3.46Å
302	L	89.3	Confident	92.1	Very high	3 Å²	3	15.4 Å²	15.4	2%	0.016	8%	0.078	C	C	.	.	H	α-helix	trans	-68	-23.1	174.9	-63.7	177.7	0	0	0	112.7	L60 R63 I121 M128 V298 Q299 R300 G304	L60-L302 HydrophobicContact CD2-CB 3.95Å; R63-L302 WeakPolarHBondContact CD-O 3.29Å; R63-L302 WeakPolarHBondContact CG-O 3.24Å; R63-L302 PolarHBondContact NE-O 3.18Å; I121-L302 HydrophobicContact CG1-CD2 3.78Å; M128-L302 HydrophobicContact CE-CD1 4.13Å; V298-L302 HydrophobicContact CG1-CD1 4.39Å; V298-L302 HydrophobicContact CG1-CG 4.3Å; V298-L302 WeakPolarHBondContact O-CG 3.32Å; V298-L302 PolarHBondContact O-N 2.9Å; Q299-L302 PolarHBondContact O-N 2.75Å; R300-L302 PolarHBondContact O-N 3.06Å; L302-G304 PolarHBondContact O-N 2.93Å
303	S	86.6	Confident	92.1	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.078	C	C	.	.	T	Hydrogen-bonded Turn	trans	-76.6	-2.4	176.4	76.9	0	0	0	0	114.9	L60 R63 V65 Q299 R300 C301	L60-S303 VanDerWaalsContact O-CB 3.29Å; L60-S303 WeakPolarHBondContact O-CB 3.18Å; R63-S303 CarbonylContact C-O 3.53Å; R63-S303 VanDerWaalsContact CA-O 3.26Å; R63-S303 WeakPolarHBondContact CA-O 3.48Å; V65-S303 WeakPolarHBondContact CB-O 3.25Å; V65-S303 WeakPolarHBondContact CG2-O 3.49Å; V65-S303 PolarHBondContact N-O 3.18Å; Q299-S303 PolarHBondContact O-N 2.75Å; R300-S303 WeakPolarHBondContact O-CB 3.28Å; R300-S303 PolarHBondContact O-N 3.14Å; R300-S303 PolarHBondContact O-OG 2.56Å; C301-S303 PolarHBondContact O-N 3.11Å
304	G	87.8	Confident	92.3	Very high	3 Å²	3	15.1 Å²	15.1	3%	0.031	8%	0.076	C	C	.	.	B	Isolated β-bridge	trans	-68.9	144.5	-179.6	0	0	0	0	0	113.8	C301 L302	C301-G304 PolarHBondContact O-N 3.4Å; L302-G304 PolarHBondContact O-N 2.93Å
305	K	86.4	Confident	92.6	Very high	124 Å²	124	14.8 Å²	14.8	54%	0.539	7%	0.074	S	C	.	.	S	Bend	trans	-62.3	-42	179.5	-176.5	175	-172.3	150.2	0	114.2	R63 D64 V65	R63-K305 WeakPolarHBondContact O-CA 3.25Å; D64-K305 WeakPolarHBondContact OD1-CD 3.27Å; D64-K305 WeakPolarHBondContact OD1-CE 3.32Å; D64-K305 IonicContact OD1-NZ 3.3Å; D64-K305 PolarHBondContact OD1-NZ 3.43Å; V65-K305 PolarHBondContact O-N 2.97Å
306	D	90.2	Very high	92.9	Very high	59 Å²	59	16.2 Å²	16.2	32%	0.316	8%	0.082	S	C	.	.	S	Bend	trans	-153	171.1	177.7	65	56	0	0	0	110.7	S308 H309 V310	D306-S308 VanDerWaalsContact C-N 3.32Å; D306-S308 PolarHBondContact O-N 3.42Å; D306-S308 WeakPolarHBondContact OD1-CA 3.46Å; D306-S308 WeakPolarHBondContact OD1-CB 3.31Å; D306-S308 PolarHBondContact OD1-N 2.84Å; D306-H309 WeakPolarHBondContact O-CB 3.23Å; D306-H309 PolarHBondContact O-N 2.89Å; D306-H309 IonicContact OD1-CD2 2.73Å; D306-H309 PolarHBondContact OD1-CD2 3.29Å; D306-H309 VanDerWaalsContact OD1-CD2 3.3Å; D306-H309 IonicContact OD1-CG 2.74Å; D306-H309 PolarHBondContact OD1-N 3.47Å; D306-H309 IonicContact OD2-CD2 3.7Å; D306-H309 PolarHBondContact OD2-CD2 3.2Å; D306-H309 IonicContact OD2-NE2 3.98Å; D306-V310 WeakPolarHBondContact O-CG2 3.37Å; D306-V310 PolarHBondContact O-N 2.91Å; D306-V310 VanDerWaalsContact O-N 3.1Å
307	M	92.9	Very high	93.3	Very high	4 Å²	4	16.1 Å²	16.1	2%	0.02	8%	0.081	C	C	.	.	H	α-helix	trans	-64.7	-33.8	-174.7	-167.9	70.3	-126.7	0	0	113.1	G113 V117 P118 I121 V310 K311 E632	G113-M307 WeakPolarHBondContact O-CE 3.49Å; V117-M307 HydrophobicContact CB-CE 4.35Å; V117-M307 HydrophobicContact CG1-CE 4.14Å; P118-M307 HydrophobicContact CB-SD 4.26Å; P118-M307 HydrophobicContact CG-CE 3.65Å; P118-M307 HydrophobicContact CG-SD 3.89Å; I121-M307 HydrophobicContact CD1-SD 4.23Å; M307-V310 HydrophobicContact CE-CB 4.42Å; M307-V310 PolarHBondContact O-N 2.89Å; M307-K311 HydrophobicContact CE-CD 4.43Å; M307-K311 HydrophobicContact CE-CG 3.93Å; M307-K311 WeakPolarHBondContact O-CG 3.24Å; M307-K311 PolarHBondContact O-N 2.8Å; M307-E632 HydrophobicContact CB-CG 3.71Å; M307-E632 HydrophobicContact CG-CG 4.08Å
308	S	95.1	Very high	93.5	Very high	10 Å²	10	16.1 Å²	16.1	7%	0.07	8%	0.081	C	C	.	.	H	α-helix	trans	-69.8	-37.2	177.7	-64.5	0	0	0	0	111.2	D306 K311 A312 E632	D306-S308 VanDerWaalsContact C-N 3.32Å; D306-S308 PolarHBondContact O-N 3.42Å; D306-S308 WeakPolarHBondContact OD1-CA 3.46Å; D306-S308 WeakPolarHBondContact OD1-CB 3.31Å; D306-S308 PolarHBondContact OD1-N 2.84Å; S308-K311 PolarHBondContact O-N 3.26Å; S308-A312 VanDerWaalsContact O-CB 3.29Å; S308-A312 WeakPolarHBondContact O-CB 3.48Å; S308-A312 PolarHBondContact O-N 3.03Å; S308-E632 WeakPolarHBondContact CA-OE1 3.41Å; S308-E632 PolarHBondContact N-OE1 2.79Å; S308-E632 WeakPolarHBondContact OG-CG 3.2Å; S308-E632 PolarHBondContact OG-OE1 3.36Å
309	H	94.8	Very high	93.7	Very high	49 Å²	49	19.3 Å²	19.3	23%	0.227	9%	0.094	C	C	.	.	H	α-helix	trans	-63.7	-40.8	173	-86.4	-106.3	0	0	0	112.6	W67 M70 D306 A312 A313	W67-H309 HydrophobicContact CB-CB 4.26Å; W67-H309 WeakPolarHBondContact CB-O 3.41Å; W67-H309 AromaticContact CD1-CE1 3.83Å; W67-H309 AromaticContact CD1-ND1 3.75Å; W67-H309 PolarHBondContact N-ND1 3.45Å; W67-H309 VanDerWaalsContact N-ND1 3.11Å; M70-H309 HydrophobicContact CE-CB 4.48Å; D306-H309 WeakPolarHBondContact O-CB 3.23Å; D306-H309 PolarHBondContact O-N 2.89Å; D306-H309 IonicContact OD1-CD2 2.73Å; D306-H309 PolarHBondContact OD1-CD2 3.29Å; D306-H309 VanDerWaalsContact OD1-CD2 3.3Å; D306-H309 IonicContact OD1-CG 2.74Å; D306-H309 PolarHBondContact OD1-N 3.47Å; D306-H309 IonicContact OD2-CD2 3.7Å; D306-H309 PolarHBondContact OD2-CD2 3.2Å; D306-H309 IonicContact OD2-NE2 3.98Å; H309-A312 PolarHBondContact O-N 3.44Å; H309-A313 WeakPolarHBondContact O-CB 3.26Å; H309-A313 PolarHBondContact O-N 3.48Å
310	V	95.8	Very high	94.1	Very high	0 Å²	0	20.7 Å²	20.7	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-66.7	-43.9	177.2	-179.7	0	0	0	0	111.5	M70 V117 C301 D306 M307 A312 A313 C314	M70-V310 HydrophobicContact CE-CG2 4.31Å; M70-V310 HydrophobicContact SD-CB 4.49Å; M70-V310 HydrophobicContact SD-CG2 4.15Å; V117-V310 HydrophobicContact CB-CG1 4.43Å; V117-V310 HydrophobicContact CG1-CG1 3.83Å; V117-V310 HydrophobicContact CG2-CG1 4.32Å; C301-V310 HydrophobicContact CB-CG1 3.85Å; C301-V310 WeakPolarHBondContact O-CG2 3.46Å; D306-V310 WeakPolarHBondContact O-CG2 3.37Å; D306-V310 PolarHBondContact O-N 2.91Å; D306-V310 VanDerWaalsContact O-N 3.1Å; M307-V310 HydrophobicContact CE-CB 4.42Å; M307-V310 PolarHBondContact O-N 2.89Å; V310-A312 PolarHBondContact O-N 2.86Å; V310-A313 WeakPolarHBondContact O-CB 3.46Å; V310-A313 PolarHBondContact O-N 3.43Å; V310-C314 PolarHBondContact O-N 3.5Å; V310-C314 PolarHBondContact O-SG 2.96Å
311	K	97.4	Very high	94.3	Very high	15 Å²	15	20.6 Å²	20.6	7%	0.065	10%	0.1	C	C	.	.	H	α-helix	trans	-61.1	-44.1	175.3	-75.3	175.6	-179.7	176.8	0	112.4	W114 M307 S308 A313 C314 I315 E632 V640	W114-K311 HydrophobicContact CD2-CD 4.04Å; W114-K311 HydrophobicContact CD2-CG 4.1Å; W114-K311 HydrophobicContact CE3-CB 4.36Å; W114-K311 HydrophobicContact CE3-CD 4.3Å; W114-K311 HydrophobicContact CE3-CG 3.86Å; W114-K311 HydrophobicContact CH2-CB 3.59Å; W114-K311 HydrophobicContact CH2-CD 4.04Å; W114-K311 HydrophobicContact CH2-CG 3.85Å; W114-K311 HydrophobicContact CZ2-CB 4.16Å; W114-K311 HydrophobicContact CZ2-CD 3.77Å; W114-K311 HydrophobicContact CZ2-CG 4.11Å; W114-K311 HydrophobicContact CZ3-CB 3.73Å; W114-K311 HydrophobicContact CZ3-CD 4.31Å; W114-K311 HydrophobicContact CZ3-CG 3.75Å; M307-K311 HydrophobicContact CE-CD 4.43Å; M307-K311 HydrophobicContact CE-CG 3.93Å; M307-K311 WeakPolarHBondContact O-CG 3.24Å; M307-K311 PolarHBondContact O-N 2.8Å; S308-K311 PolarHBondContact O-N 3.26Å; K311-A313 VanDerWaalsContact C-N 3.33Å; K311-A313 PolarHBondContact O-N 3.35Å; K311-C314 PolarHBondContact O-N 3.48Å; K311-I315 WeakPolarHBondContact O-CG1 3.38Å; K311-I315 PolarHBondContact O-N 3.4Å; K311-E632 WeakPolarHBondContact CD-OE1 3.37Å; K311-E632 VanDerWaalsContact NZ-CD 3.3Å; K311-E632 IonicContact NZ-OE1 3.58Å; K311-E632 PolarHBondContact NZ-OE1 3.45Å; K311-E632 IonicContact NZ-OE2 2.72Å; K311-E632 PolarHBondContact NZ-OE2 2.95Å; K311-V640 HydrophobicContact CB-CB 4.23Å; K311-V640 HydrophobicContact CB-CG1 4.38Å; K311-V640 HydrophobicContact CB-CG2 4.17Å; K311-V640 HydrophobicContact CD-CG2 3.96Å
312	A	97.3	Very high	94.5	Very high	20 Å²	20	21.6 Å²	21.6	17%	0.165	11%	0.106	C	C	.	.	H	α-helix	trans	-62.9	-39.1	175.8	0	0	0	0	0	112	W67 S308 H309 V310 I315 M316 V640	W67-A312 HydrophobicContact CB-CB 3.69Å; W67-A312 HydrophobicContact CD2-CB 4.27Å; W67-A312 HydrophobicContact CE3-CB 4.4Å; W67-A312 HydrophobicContact CG-CB 3.97Å; S308-A312 VanDerWaalsContact O-CB 3.29Å; S308-A312 WeakPolarHBondContact O-CB 3.48Å; S308-A312 PolarHBondContact O-N 3.03Å; H309-A312 PolarHBondContact O-N 3.44Å; V310-A312 PolarHBondContact O-N 2.86Å; A312-I315 PolarHBondContact O-N 3.35Å; A312-M316 WeakPolarHBondContact O-CB 3.39Å; A312-M316 PolarHBondContact O-N 2.84Å; A312-V640 HydrophobicContact CB-CG1 4.07Å
313	A	97.3	Very high	94.8	Very high	0 Å²	0	23.3 Å²	23.3	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-62.1	-43.6	174.4	0	0	0	0	0	112.1	W67 M70 G71 L74 H309 V310 K311 M316 C317	W67-A313 HydrophobicContact CB-CB 4.49Å; W67-A313 WeakPolarHBondContact O-CA 3.25Å; W67-A313 VanDerWaalsContact O-CB 3.3Å; W67-A313 WeakPolarHBondContact O-CB 3.45Å; M70-A313 HydrophobicContact CB-CB 3.86Å; M70-A313 HydrophobicContact CE-CB 4.11Å; M70-A313 HydrophobicContact CG-CB 3.84Å; M70-A313 HydrophobicContact SD-CB 3.58Å; M70-A313 VanDerWaalsContact SD-CB 3.58Å; G71-A313 WeakPolarHBondContact CA-O 3.43Å; L74-A313 HydrophobicContact CD1-CB 4.34Å; H309-A313 WeakPolarHBondContact O-CB 3.26Å; H309-A313 PolarHBondContact O-N 3.48Å; V310-A313 WeakPolarHBondContact O-CB 3.46Å; V310-A313 PolarHBondContact O-N 3.43Å; K311-A313 VanDerWaalsContact C-N 3.33Å; K311-A313 PolarHBondContact O-N 3.35Å; A313-M316 PolarHBondContact O-N 2.92Å; A313-C317 WeakPolarHBondContact O-CB 3.5Å; A313-C317 PolarHBondContact O-N 3.27Å
314	C	97.8	Very high	95.3	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-62.3	-44.3	176.6	-63.8	0	0	0	0	111.6	L109 V310 K311 C317 A318	L109-C314 HydrophobicContact CB-CB 4.4Å; L109-C314 HydrophobicContact CD2-CB 4.46Å; L109-C314 WeakPolarHBondContact O-CB 3.18Å; V310-C314 PolarHBondContact O-N 3.5Å; V310-C314 PolarHBondContact O-SG 2.96Å; K311-C314 PolarHBondContact O-N 3.48Å; C314-C317 PolarHBondContact O-N 3.44Å; C314-A318 WeakPolarHBondContact O-CB 3.35Å; C314-A318 PolarHBondContact O-N 3.49Å
315	I	98	Very high	95.7	Very high	9 Å²	9	23.2 Å²	23.2	5%	0.046	11%	0.114	C	C	.	.	H	α-helix	trans	-61.6	-47.7	175.4	-72.9	169.6	0	0	0	111.2	W114 K311 A312 C317 A318 Y319 V640 N643 A644	W114-I315 HydrophobicContact CH2-CD1 3.59Å; W114-I315 HydrophobicContact CH2-CG1 4.03Å; W114-I315 HydrophobicContact CZ3-CD1 4.31Å; W114-I315 HydrophobicContact CZ3-CG1 4.26Å; K311-I315 WeakPolarHBondContact O-CG1 3.38Å; K311-I315 PolarHBondContact O-N 3.4Å; A312-I315 PolarHBondContact O-N 3.35Å; I315-C317 VanDerWaalsContact C-N 3.33Å; I315-C317 PolarHBondContact O-N 3.1Å; I315-A318 WeakPolarHBondContact O-CB 3.49Å; I315-A318 PolarHBondContact O-N 3.4Å; I315-A318 VanDerWaalsContact O-N 3.09Å; I315-Y319 HydrophobicContact CG2-CD2 3.65Å; I315-Y319 HydrophobicContact CG2-CE2 3.35Å; I315-Y319 WeakPolarHBondContact O-CD2 3.28Å; I315-Y319 PolarHBondContact O-N 3.45Å; I315-V640 HydrophobicContact CD1-CB 4.11Å; I315-V640 WeakPolarHBondContact CD1-O 3.33Å; I315-N643 HydrophobicContact CD1-CB 3.93Å; I315-N643 HydrophobicContact CG2-CB 4.18Å; I315-A644 HydrophobicContact CD1-CB 4.12Å; I315-A644 HydrophobicContact CG1-CB 4.49Å
316	M	97.3	Very high	96.1	Very high	40 Å²	40	21 Å²	21	20%	0.197	10%	0.104	C	C	.	.	H	α-helix	trans	-60.4	-46.9	-179	-171	-172.8	72.9	0	0	110.6	W67 W68 A72 A312 A313 A318 Y319 L320	W67-M316 HydrophobicContact CE3-CB 4.28Å; W67-M316 HydrophobicContact CE3-SD 3.93Å; W67-M316 HydrophobicContact CH2-SD 4.39Å; W67-M316 HydrophobicContact CZ3-CB 4.11Å; W67-M316 HydrophobicContact CZ3-CG 4.04Å; W67-M316 HydrophobicContact CZ3-SD 3.43Å; W67-M316 WeakPolarHBondContact CZ3-SD 3.36Å; W68-M316 HydrophobicContact CB-SD 4.23Å; W68-M316 WeakPolarHBondContact O-CE 3.36Å; A72-M316 HydrophobicContact CB-CE 4.16Å; A312-M316 WeakPolarHBondContact O-CB 3.39Å; A312-M316 PolarHBondContact O-N 2.84Å; A313-M316 PolarHBondContact O-N 2.92Å; M316-A318 VanDerWaalsContact C-N 3.26Å; M316-A318 PolarHBondContact O-N 3.23Å; M316-Y319 PolarHBondContact O-N 3.45Å; M316-L320 WeakPolarHBondContact O-CG 3.43Å; M316-L320 PolarHBondContact O-N 2.76Å
317	C	97.5	Very high	96.4	Very high	0 Å²	0	18.4 Å²	18.4	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-57.9	-40.7	174.6	-175.5	0	0	0	0	111.3	L74 L109 A313 C314 I315 Y319 L320 K321	L74-C317 HydrophobicContact CB-CB 4.09Å; L109-C317 HydrophobicContact CD1-CB 3.89Å; L109-C317 VanDerWaalsContact CD1-SG 3.57Å; L109-C317 HydrophobicContact CD2-CB 4.3Å; A313-C317 WeakPolarHBondContact O-CB 3.5Å; A313-C317 PolarHBondContact O-N 3.27Å; C314-C317 PolarHBondContact O-N 3.44Å; I315-C317 VanDerWaalsContact C-N 3.33Å; I315-C317 PolarHBondContact O-N 3.1Å; C317-Y319 PolarHBondContact O-N 3.38Å; C317-L320 PolarHBondContact O-N 2.91Å; C317-K321 VanDerWaalsContact O-CG 3.27Å; C317-K321 WeakPolarHBondContact O-CG 3.2Å; C317-K321 PolarHBondContact O-N 3.49Å
318	A	97.4	Very high	96.5	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-67.8	-33.7	-179.5	0	0	0	0	0	113.6	S106 L109 C314 I315 M316 K321 L647	S106-A318 PolarHBondContact OG-O 2.92Å; L109-A318 HydrophobicContact CB-CB 4Å; L109-A318 HydrophobicContact CD1-CB 3.84Å; C314-A318 WeakPolarHBondContact O-CB 3.35Å; C314-A318 PolarHBondContact O-N 3.49Å; I315-A318 WeakPolarHBondContact O-CB 3.49Å; I315-A318 PolarHBondContact O-N 3.4Å; I315-A318 VanDerWaalsContact O-N 3.09Å; M316-A318 VanDerWaalsContact C-N 3.26Å; M316-A318 PolarHBondContact O-N 3.23Å; A318-K321 PolarHBondContact O-N 3.17Å; A318-L647 HydrophobicContact CB-CD1 4.01Å; A318-L647 HydrophobicContact CB-CD2 3.38Å; A318-L647 HydrophobicContact CB-CG 4.29Å
319	Y	97.1	Very high	96.6	Very high	67 Å²	67	17.8 Å²	17.8	26%	0.263	9%	0.086	S	C	.	.	H	α-helix	trans	-67.2	-44.2	169.5	-78.5	-61	0	0	0	111.7	I315 M316 C317 K321 L322 N643 L646 L647	I315-Y319 HydrophobicContact CG2-CD2 3.65Å; I315-Y319 HydrophobicContact CG2-CE2 3.35Å; I315-Y319 WeakPolarHBondContact O-CD2 3.28Å; I315-Y319 PolarHBondContact O-N 3.45Å; M316-Y319 PolarHBondContact O-N 3.45Å; C317-Y319 PolarHBondContact O-N 3.38Å; Y319-K321 PolarHBondContact O-N 3.12Å; Y319-L322 HydrophobicContact CD1-CD1 4.41Å; Y319-L322 WeakPolarHBondContact O-CB 3.42Å; Y319-L322 PolarHBondContact O-N 3.44Å; Y319-N643 PolarHBondContact OH-O 3.04Å; Y319-L646 VanDerWaalsContact OH-CD2 3.3Å; Y319-L646 WeakPolarHBondContact OH-CD2 3.23Å; Y319-L647 HydrophobicContact CD1-CD1 3.64Å; Y319-L647 HydrophobicContact CD2-CD1 4.49Å; Y319-L647 HydrophobicContact CE1-CB 4.04Å; Y319-L647 HydrophobicContact CE1-CD1 3.69Å; Y319-L647 HydrophobicContact CE1-CG 4.49Å; Y319-L647 HydrophobicContact CE2-CB 4.43Å; Y319-L647 HydrophobicContact CG-CD1 4.05Å; Y319-L647 PolarHBondContact OH-N 3.27Å
320	L	96.6	Very high	96.8	Very high	29 Å²	29	15.5 Å²	15.5	15%	0.152	8%	0.076	C	C	.	.	H	α-helix	trans	-60.6	-31.9	176.4	-66.9	178.4	0	0	0	111.7	F75 T208 L212 M316 C317 L322 L323 P324	F75-L320 HydrophobicContact CB-CB 4.5Å; F75-L320 HydrophobicContact CB-CD1 3.94Å; F75-L320 HydrophobicContact CD1-CD1 4.21Å; F75-L320 HydrophobicContact CD2-CB 3.47Å; F75-L320 VanDerWaalsContact CD2-CB 3.47Å; F75-L320 HydrophobicContact CD2-CD1 4.31Å; F75-L320 HydrophobicContact CE2-CB 3.67Å; F75-L320 WeakPolarHBondContact CE2-O 3.01Å; F75-L320 HydrophobicContact CG-CB 3.95Å; F75-L320 HydrophobicContact CG-CD1 3.91Å; F75-L320 HydrophobicContact CZ-CB 4.31Å; T208-L320 HydrophobicContact CG2-CD1 4.37Å; L212-L320 HydrophobicContact CD1-CD2 3.67Å; M316-L320 WeakPolarHBondContact O-CG 3.43Å; M316-L320 PolarHBondContact O-N 2.76Å; C317-L320 PolarHBondContact O-N 2.91Å; L320-L322 PolarHBondContact O-N 3.37Å; L320-L323 HydrophobicContact CD2-CD1 3.97Å; L320-L323 WeakPolarHBondContact O-CB 3.31Å; L320-L323 PolarHBondContact O-N 3.38Å; L320-L323 VanDerWaalsContact O-N 3.13Å; L320-P324 WeakPolarHBondContact O-CD 3.37Å
321	K	95.9	Very high	96.8	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	8%	0.076	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.8	-9.4	175.4	-75.5	-72.1	175.8	-173.3	0	115.5	F75 N78 I79 E102 L109 W291 C317 A318 Y319 P324	F75-K321 HydrophobicContact CD2-CD 4.48Å; F75-K321 HydrophobicContact CD2-CG 4.5Å; N78-K321 VanDerWaalsContact OD1-CE 3.29Å; N78-K321 WeakPolarHBondContact OD1-CE 3.41Å; N78-K321 PolarHBondContact OD1-NZ 2.8Å; I79-K321 VanDerWaalsContact CG1-NZ 3.32Å; E102-K321 WeakPolarHBondContact OE2-CD 3.16Å; E102-K321 WeakPolarHBondContact OE2-CE 3.44Å; E102-K321 IonicContact OE2-NZ 2.63Å; E102-K321 PolarHBondContact OE2-NZ 2.65Å; L109-K321 HydrophobicContact CD1-CG 4.29Å; W291-K321 HydrophobicContact CZ2-CD 4.46Å; C317-K321 VanDerWaalsContact O-CG 3.27Å; C317-K321 WeakPolarHBondContact O-CG 3.2Å; C317-K321 PolarHBondContact O-N 3.49Å; A318-K321 PolarHBondContact O-N 3.17Å; Y319-K321 PolarHBondContact O-N 3.12Å; K321-P324 VanDerWaalsContact O-CD 3.26Å; K321-P324 WeakPolarHBondContact O-CD 3.44Å
322	L	95.8	Very high	96.8	Very high	22 Å²	22	14.8 Å²	14.8	12%	0.115	7%	0.072	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79.8	-24.4	171.2	-57.2	-175.4	0	0	0	112.4	W103 S106 Y319 L320 P324 V650 V651 I654	W103-L322 PolarHBondContact NE1-O 2.87Å; S106-L322 WeakPolarHBondContact OG-CD2 3.5Å; Y319-L322 HydrophobicContact CD1-CD1 4.41Å; Y319-L322 WeakPolarHBondContact O-CB 3.42Å; Y319-L322 PolarHBondContact O-N 3.44Å; L320-L322 PolarHBondContact O-N 3.37Å; L322-P324 VanDerWaalsContact C-CD 3.46Å; L322-V650 HydrophobicContact CD1-CG1 3.75Å; L322-V651 HydrophobicContact CD2-CG2 4.12Å; L322-I654 HydrophobicContact CD2-CD1 3.51Å
323	L	96.4	Very high	96.9	Very high	39 Å²	39	13.9 Å²	13.9	20%	0.204	7%	0.065	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.7	-30.6	-173.4	-57.4	178.8	0	0	0	116.4	L212 F216 L320 M325 F326 L327	L212-L323 HydrophobicContact CD2-CD1 3.83Å; F216-L323 HydrophobicContact CE2-CD1 4.3Å; F216-L323 HydrophobicContact CZ-CD1 4.1Å; F216-L323 HydrophobicContact CZ-CD2 4.01Å; L320-L323 HydrophobicContact CD2-CD1 3.97Å; L320-L323 WeakPolarHBondContact O-CB 3.31Å; L320-L323 PolarHBondContact O-N 3.38Å; L320-L323 VanDerWaalsContact O-N 3.13Å; L323-M325 PolarHBondContact O-N 2.77Å; L323-F326 PolarHBondContact O-N 2.91Å; L323-L327 HydrophobicContact CB-CD1 3.7Å; L323-L327 HydrophobicContact CB-CG 4.1Å; L323-L327 HydrophobicContact CD1-CD1 4.26Å; L323-L327 WeakPolarHBondContact O-CG 3.38Å; L323-L327 PolarHBondContact O-N 2.74Å
324	P	96.1	Very high	96.9	Very high	1 Å²	1	13.9 Å²	13.9	1%	0.006	7%	0.065	C	C	.	.	H	α-helix	trans	-54.3	-26.3	-177.3	-30.2	37.4	0	0	0	115.1	I79 L87 E102 L320 K321 L322 F326 M328 V329	I79-P324 HydrophobicContact CD1-CG 4.24Å; L87-P324 HydrophobicContact CD1-CB 4.17Å; E102-P324 HydrophobicContact CB-CB 4.32Å; E102-P324 HydrophobicContact CB-CG 4.21Å; E102-P324 HydrophobicContact CG-CB 3.84Å; E102-P324 HydrophobicContact CG-CG 3.97Å; L320-P324 WeakPolarHBondContact O-CD 3.37Å; K321-P324 VanDerWaalsContact O-CD 3.26Å; K321-P324 WeakPolarHBondContact O-CD 3.44Å; L322-P324 VanDerWaalsContact C-CD 3.46Å; P324-F326 VanDerWaalsContact C-N 3.32Å; P324-F326 PolarHBondContact O-N 2.99Å; P324-M328 HydrophobicContact CB-SD 4.22Å; P324-M328 WeakPolarHBondContact O-CA 2.98Å; P324-M328 WeakPolarHBondContact O-CB 3.46Å; P324-M328 PolarHBondContact O-N 2.95Å; P324-V329 PolarHBondContact O-N 2.85Å
325	M	95.8	Very high	96.9	Very high	0 Å²	0	13.9 Å²	13.9	0%	0	7%	0.065	C	C	.	.	I	π-helix	trans	-52.2	-53	172	-163.5	-178.4	-169.2	0	0	111.7	V96 V99 W103 L323 V329 M330 Y658	V96-M325 HydrophobicContact CB-CE 4.03Å; V96-M325 HydrophobicContact CG1-CE 4.14Å; V99-M325 HydrophobicContact CB-CG 4.45Å; V99-M325 HydrophobicContact CG2-CB 3.6Å; V99-M325 HydrophobicContact CG2-CG 3.94Å; W103-M325 HydrophobicContact CH2-CE 4.3Å; W103-M325 HydrophobicContact CH2-SD 3.6Å; W103-M325 VanDerWaalsContact CH2-SD 3.6Å; W103-M325 HydrophobicContact CZ2-CB 4.11Å; W103-M325 HydrophobicContact CZ2-CG 4.2Å; W103-M325 HydrophobicContact CZ2-SD 3.38Å; W103-M325 WeakPolarHBondContact CZ2-SD 3.32Å; L323-M325 PolarHBondContact O-N 2.77Å; M325-V329 WeakPolarHBondContact O-CB 3.39Å; M325-V329 PolarHBondContact O-N 3.09Å; M325-M330 HydrophobicContact CE-CE 3.71Å; M325-M330 HydrophobicContact CG-CE 4.08Å; M325-M330 WeakPolarHBondContact O-CG 3.5Å; M325-M330 PolarHBondContact O-N 3.41Å; M325-M330 HydrophobicContact SD-CE 4.07Å; M325-Y658 HydrophobicContact CE-CD1 3.68Å; M325-Y658 HydrophobicContact CE-CD2 3.85Å; M325-Y658 HydrophobicContact CE-CE1 3.24Å; M325-Y658 HydrophobicContact CE-CE2 3.42Å; M325-Y658 VanDerWaalsContact CE-CE2 3.42Å; M325-Y658 HydrophobicContact CE-CG 3.97Å; M325-Y658 WeakPolarHBondContact CE-OH 3.4Å; M325-Y658 HydrophobicContact SD-CD2 4.27Å; M325-Y658 HydrophobicContact SD-CE1 4.42Å; M325-Y658 HydrophobicContact SD-CE2 3.6Å; M325-Y658 VanDerWaalsContact SD-CE2 3.6Å
326	F	95.9	Very high	96.9	Very high	78 Å²	78	13.9 Å²	13.9	34%	0.342	6%	0.064	S	C	.	.	I	π-helix	trans	-86.9	-30.1	-173.2	-53.2	-75.4	0	0	0	111.7	M219 L323 P324 M330 P331	M219-F326 WeakPolarHBondContact CG-O 3.31Å; M219-F326 HydrophobicContact SD-CB 3.62Å; L323-F326 PolarHBondContact O-N 2.91Å; P324-F326 VanDerWaalsContact C-N 3.32Å; P324-F326 PolarHBondContact O-N 2.99Å; F326-M330 HydrophobicContact CD1-CE 3.99Å; F326-M330 HydrophobicContact CD1-SD 3.65Å; F326-M330 HydrophobicContact CE1-CE 3.92Å; F326-M330 HydrophobicContact CE1-SD 4.18Å; F326-P331 WeakPolarHBondContact O-CD 3.18Å; F326-P331 WeakPolarHBondContact O-CG 3.3Å
327	L	96.3	Very high	96.9	Very high	3 Å²	3	13.2 Å²	13.2	2%	0.016	6%	0.061	C	C	.	.	I	π-helix	trans	-90.8	-17.9	-174.3	-62	-171.2	0	0	0	114.2	L212 F216 M219 L323 Y366	L212-L327 HydrophobicContact CD2-CD1 3.77Å; F216-L327 HydrophobicContact CB-CD2 4.48Å; F216-L327 HydrophobicContact CD1-CD2 3.64Å; F216-L327 HydrophobicContact CD2-CD2 4.31Å; F216-L327 HydrophobicContact CE1-CD2 3.83Å; F216-L327 HydrophobicContact CE2-CD1 4.21Å; F216-L327 HydrophobicContact CE2-CD2 4.45Å; F216-L327 HydrophobicContact CG-CD2 3.88Å; F216-L327 HydrophobicContact CZ-CD1 4.32Å; F216-L327 HydrophobicContact CZ-CD2 4.22Å; M219-L327 HydrophobicContact CB-CD2 4.44Å; M219-L327 HydrophobicContact SD-CD2 4.11Å; L323-L327 HydrophobicContact CB-CD1 3.7Å; L323-L327 HydrophobicContact CB-CG 4.1Å; L323-L327 HydrophobicContact CD1-CD1 4.26Å; L323-L327 WeakPolarHBondContact O-CG 3.38Å; L323-L327 PolarHBondContact O-N 2.74Å; L327-Y366 VanDerWaalsContact O-CE2 3.31Å; L327-Y366 WeakPolarHBondContact O-CE2 3.32Å
328	M	95.6	Very high	96.9	Very high	2 Å²	2	16 Å²	16	1%	0.01	8%	0.076	C	C	.	.	I	π-helix	trans	-135.4	-55.5	-175	-56	177.1	-172.4	0	0	112.4	I79 H83 Y84 L87 A88 P324 G332	I79-M328 HydrophobicContact CG2-CE 3.29Å; H83-M328 HydrophobicContact CB-SD 4.12Å; Y84-M328 HydrophobicContact CD1-CE 4.01Å; Y84-M328 HydrophobicContact CD1-CG 3.9Å; Y84-M328 HydrophobicContact CD1-SD 4.25Å; Y84-M328 HydrophobicContact CD2-CE 3.95Å; Y84-M328 HydrophobicContact CE1-CE 3.59Å; Y84-M328 HydrophobicContact CE1-CG 3.89Å; Y84-M328 HydrophobicContact CE1-SD 4.33Å; Y84-M328 HydrophobicContact CE2-CE 3.5Å; Y84-M328 VanDerWaalsContact CE2-CE 3.5Å; Y84-M328 HydrophobicContact CG-CE 4.19Å; Y84-M328 HydrophobicContact CG-SD 4.41Å; L87-M328 HydrophobicContact CB-CB 4.4Å; L87-M328 HydrophobicContact CD1-SD 3.99Å; A88-M328 WeakPolarHBondContact CB-O 3.3Å; P324-M328 HydrophobicContact CB-SD 4.22Å; P324-M328 WeakPolarHBondContact O-CA 2.98Å; P324-M328 WeakPolarHBondContact O-CB 3.46Å; P324-M328 PolarHBondContact O-N 2.95Å; M328-G332 PolarHBondContact O-N 2.83Å
329	V	97.4	Very high	96.8	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	9%	0.086	C	C	.	.	I	π-helix	trans	-64.8	-54	-173.6	179.7	0	0	0	0	111.1	L87 T98 V99 P324 M325 G332 M333	L87-V329 HydrophobicContact CB-CG2 4.3Å; T98-V329 HydrophobicContact CG2-CB 4.37Å; T98-V329 HydrophobicContact CG2-CG1 3.75Å; T98-V329 HydrophobicContact CG2-CG2 3.68Å; V99-V329 HydrophobicContact CB-CG2 4.42Å; P324-V329 PolarHBondContact O-N 2.85Å; M325-V329 WeakPolarHBondContact O-CB 3.39Å; M325-V329 PolarHBondContact O-N 3.09Å; V329-G332 WeakPolarHBondContact O-CA 3.25Å; V329-G332 PolarHBondContact O-N 3.05Å; V329-G332 VanDerWaalsContact O-N 3.14Å; V329-M333 HydrophobicContact CG1-SD 4.38Å; V329-M333 WeakPolarHBondContact O-CG 3.48Å; V329-M333 PolarHBondContact O-N 3.19Å
330	M	97.4	Very high	96.7	Very high	1 Å²	1	16.6 Å²	16.6	1%	0.005	8%	0.081	C	C	.	.	H	α-helix	trans	-63.6	-44.6	177.9	-70.8	176.6	-178.8	0	0	112.8	F223 Y229 F232 M325 F326 G332 M333 I334	F223-M330 HydrophobicContact CE2-CB 4.37Å; F223-M330 HydrophobicContact CE2-SD 4.32Å; F223-M330 HydrophobicContact CZ-CB 4.06Å; F223-M330 HydrophobicContact CZ-CG 4.42Å; F223-M330 HydrophobicContact CZ-SD 3.72Å; Y229-M330 HydrophobicContact CE2-CE 3.8Å; Y229-M330 HydrophobicContact CE2-SD 4.24Å; F232-M330 HydrophobicContact CE1-CG 4.39Å; F232-M330 HydrophobicContact CZ-CB 4.44Å; F232-M330 HydrophobicContact CZ-CG 4.3Å; M325-M330 HydrophobicContact CE-CE 3.71Å; M325-M330 HydrophobicContact CG-CE 4.08Å; M325-M330 WeakPolarHBondContact O-CG 3.5Å; M325-M330 PolarHBondContact O-N 3.41Å; M325-M330 HydrophobicContact SD-CE 4.07Å; F326-M330 HydrophobicContact CD1-CE 3.99Å; F326-M330 HydrophobicContact CD1-SD 3.65Å; F326-M330 HydrophobicContact CE1-CE 3.92Å; F326-M330 HydrophobicContact CE1-SD 4.18Å; M330-G332 PolarHBondContact O-N 3.39Å; M330-M333 WeakPolarHBondContact O-CB 3.31Å; M330-M333 PolarHBondContact O-N 3.43Å; M330-M333 VanDerWaalsContact O-N 3.11Å; M330-I334 WeakPolarHBondContact O-CG1 3.29Å; M330-I334 PolarHBondContact O-N 3.07Å
331	P	97.3	Very high	96.6	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-56.6	-35.1	170.3	-31.2	37.7	0	0	0	113.9	F326 I334 S335 Y366	F326-P331 WeakPolarHBondContact O-CD 3.18Å; F326-P331 WeakPolarHBondContact O-CG 3.3Å; P331-I334 PolarHBondContact O-N 3.45Å; P331-S335 WeakPolarHBondContact O-CB 3.37Å; P331-S335 PolarHBondContact O-N 3.39Å; P331-Y366 HydrophobicContact CB-CD2 4.32Å; P331-Y366 HydrophobicContact CB-CE2 4.17Å
332	G	97.2	Very high	96.4	Very high	0 Å²	0	20.4 Å²	20.4	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-63.8	-46	171.8	0	0	0	0	0	112.8	A88 A92 M328 V329 M330 I334 S335 R336	A88-G332 WeakPolarHBondContact O-CA 3.32Å; A92-G332 VanDerWaalsContact CB-O 3.25Å; A92-G332 WeakPolarHBondContact CB-O 3.28Å; M328-G332 PolarHBondContact O-N 2.83Å; V329-G332 WeakPolarHBondContact O-CA 3.25Å; V329-G332 PolarHBondContact O-N 3.05Å; V329-G332 VanDerWaalsContact O-N 3.14Å; M330-G332 PolarHBondContact O-N 3.39Å; G332-I334 VanDerWaalsContact C-N 3.33Å; G332-I334 PolarHBondContact O-N 2.87Å; G332-S335 VanDerWaalsContact O-CB 3.24Å; G332-S335 WeakPolarHBondContact O-CB 3.26Å; G332-S335 PolarHBondContact O-N 3.35Å; G332-R336 PolarHBondContact O-N 3.39Å
333	M	98.1	Very high	96.3	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-60.7	-41.5	173.5	-66	174.1	74.9	0	0	112.1	G91 V96 F232 Y236 F263 V329 M330 S335 R336 I337	G91-M333 WeakPolarHBondContact O-CG 3.49Å; V96-M333 HydrophobicContact CG1-CE 4.24Å; V96-M333 HydrophobicContact CG1-SD 3.75Å; F232-M333 HydrophobicContact CE2-CB 3.55Å; F232-M333 HydrophobicContact CE2-CE 4.46Å; F232-M333 HydrophobicContact CZ-CB 3.73Å; F232-M333 HydrophobicContact CZ-CE 3.8Å; F232-M333 HydrophobicContact CZ-CG 4.41Å; F232-M333 HydrophobicContact CZ-SD 3.85Å; Y236-M333 HydrophobicContact CD1-CE 3.64Å; Y236-M333 HydrophobicContact CD2-CB 3.66Å; Y236-M333 HydrophobicContact CD2-CE 3.89Å; Y236-M333 HydrophobicContact CD2-CG 4.16Å; Y236-M333 HydrophobicContact CE1-CE 3.63Å; Y236-M333 HydrophobicContact CE2-CB 3.67Å; Y236-M333 HydrophobicContact CE2-CE 3.88Å; Y236-M333 HydrophobicContact CE2-CG 3.74Å; Y236-M333 HydrophobicContact CG-CE 3.76Å; F263-M333 HydrophobicContact CD1-CE 4.15Å; F263-M333 HydrophobicContact CE1-CE 3.37Å; F263-M333 HydrophobicContact CE2-CE 4.34Å; F263-M333 HydrophobicContact CZ-CE 3.48Å; F263-M333 VanDerWaalsContact CZ-CE 3.48Å; V329-M333 HydrophobicContact CG1-SD 4.38Å; V329-M333 WeakPolarHBondContact O-CG 3.48Å; V329-M333 PolarHBondContact O-N 3.19Å; M330-M333 WeakPolarHBondContact O-CB 3.31Å; M330-M333 PolarHBondContact O-N 3.43Å; M330-M333 VanDerWaalsContact O-N 3.11Å; M333-S335 VanDerWaalsContact C-N 3.33Å; M333-S335 PolarHBondContact O-N 2.96Å; M333-R336 WeakPolarHBondContact O-CB 3.38Å; M333-R336 PolarHBondContact O-N 2.87Å; M333-I337 PolarHBondContact O-N 3.06Å
334	I	98.3	Very high	96.2	Very high	0 Å²	0	17.8 Å²	17.8	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-64.5	-38.8	175.1	-69.2	167.7	0	0	0	111.1	A222 F223 V226 F232 M330 P331 G332 R336 I337 L338 M369	A222-I334 HydrophobicContact CB-CB 4.44Å; A222-I334 HydrophobicContact CB-CD1 3.77Å; A222-I334 HydrophobicContact CB-CG2 3.97Å; F223-I334 HydrophobicContact CD1-CD1 4.04Å; F223-I334 HydrophobicContact CD2-CD1 4.19Å; F223-I334 HydrophobicContact CE1-CD1 4.05Å; F223-I334 HydrophobicContact CE2-CD1 4.2Å; F223-I334 HydrophobicContact CG-CD1 4.11Å; F223-I334 HydrophobicContact CZ-CD1 4.13Å; V226-I334 HydrophobicContact CG1-CB 4.37Å; V226-I334 HydrophobicContact CG1-CG1 4.23Å; V226-I334 HydrophobicContact CG1-CG2 3.55Å; V226-I334 HydrophobicContact CG2-CD1 4.2Å; V226-I334 HydrophobicContact CG2-CG1 4.24Å; F232-I334 HydrophobicContact CD2-CD1 4.25Å; F232-I334 HydrophobicContact CD2-CG1 3.49Å; F232-I334 VanDerWaalsContact CD2-CG1 3.49Å; F232-I334 HydrophobicContact CE2-CG1 3.66Å; F232-I334 HydrophobicContact CG-CG1 4.46Å; M330-I334 WeakPolarHBondContact O-CG1 3.29Å; M330-I334 PolarHBondContact O-N 3.07Å; P331-I334 PolarHBondContact O-N 3.45Å; G332-I334 VanDerWaalsContact C-N 3.33Å; G332-I334 PolarHBondContact O-N 2.87Å; I334-R336 PolarHBondContact O-N 3.46Å; I334-I337 WeakPolarHBondContact O-CA 2.89Å; I334-I337 WeakPolarHBondContact O-CB 3.42Å; I334-I337 PolarHBondContact O-N 2.98Å; I334-L338 HydrophobicContact CG2-CD1 3.85Å; I334-L338 HydrophobicContact CG2-CG 4.15Å; I334-L338 PolarHBondContact O-N 2.87Å; I334-M369 HydrophobicContact CB-CE 4.41Å; I334-M369 HydrophobicContact CG2-CE 3.71Å; I334-M369 HydrophobicContact CG2-SD 4.32Å
335	S	97.6	Very high	96	Very high	0 Å²	0	18.1 Å²	18.1	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-56.8	-40.1	174.8	-167.1	0	0	0	0	112.2	P331 G332 M333 I337 L338 Y339 A365 M369	P331-S335 WeakPolarHBondContact O-CB 3.37Å; P331-S335 PolarHBondContact O-N 3.39Å; G332-S335 VanDerWaalsContact O-CB 3.24Å; G332-S335 WeakPolarHBondContact O-CB 3.26Å; G332-S335 PolarHBondContact O-N 3.35Å; M333-S335 VanDerWaalsContact C-N 3.33Å; M333-S335 PolarHBondContact O-N 2.96Å; S335-I337 VanDerWaalsContact C-N 3.3Å; S335-I337 PolarHBondContact O-N 3.18Å; S335-L338 PolarHBondContact O-N 2.67Å; S335-Y339 WeakPolarHBondContact O-CB 2.91Å; S335-Y339 PolarHBondContact O-N 3.27Å; S335-A365 VanDerWaalsContact OG-CA 3.27Å; S335-A365 WeakPolarHBondContact OG-CA 3.49Å; S335-A365 PolarHBondContact OG-O 2.02Å; S335-M369 VanDerWaalsContact CA-SD 3.58Å; S335-M369 VanDerWaalsContact CB-CG 3.45Å
336	R	97.3	Very high	95.6	Very high	9 Å²	9	19 Å²	19	3%	0.034	9%	0.094	C	C	.	.	H	α-helix	trans	-62.7	-35.5	174.1	176.1	171.1	-178	160.1	4.1	112.5	A92 A93 Y236 A239 Y256 G332 M333 I334 T340 V343 A344	A92-R336 HydrophobicContact CB-CB 4.27Å; A92-R336 WeakPolarHBondContact O-CD 3.42Å; A92-R336 PolarHBondContact O-NH1 3.01Å; A93-R336 PolarHBondContact O-NH1 2.75Å; A93-R336 VanDerWaalsContact O-NH1 3.08Å; Y236-R336 HydrophobicContact CE2-CB 4.47Å; A239-R336 HydrophobicContact CB-CG 3.84Å; A239-R336 PolarHBondContact O-NE 3.24Å; A239-R336 VanDerWaalsContact O-NE 3.12Å; Y256-R336 PolarHBondContact O-NH2 3.03Å; G332-R336 PolarHBondContact O-N 3.39Å; M333-R336 WeakPolarHBondContact O-CB 3.38Å; M333-R336 PolarHBondContact O-N 2.87Å; I334-R336 PolarHBondContact O-N 3.46Å; R336-T340 WeakPolarHBondContact O-CA 3.29Å; R336-T340 WeakPolarHBondContact O-CB 3.42Å; R336-T340 PolarHBondContact O-N 2.92Å; R336-T340 PolarHBondContact O-OG1 3.31Å; R336-V343 HydrophobicContact CB-CG1 4.26Å; R336-A344 HydrophobicContact CG-CB 4.12Å
337	I	97.8	Very high	95.4	Very high	27 Å²	27	15.4 Å²	15.4	14%	0.138	8%	0.079	C	C	.	.	H	α-helix	trans	-67.8	-45.8	177.1	-62.2	167.8	0	0	0	111.1	V226 F232 K235 A239 M333 I334 S335 T340	V226-I337 HydrophobicContact CG1-CB 4.44Å; V226-I337 HydrophobicContact CG1-CD1 4.19Å; V226-I337 HydrophobicContact CG1-CG2 4.15Å; F232-I337 HydrophobicContact CD2-CD1 3.69Å; F232-I337 HydrophobicContact CE2-CD1 4.21Å; K235-I337 HydrophobicContact CB-CD1 3.9Å; K235-I337 HydrophobicContact CB-CG1 4.22Å; K235-I337 HydrophobicContact CB-CG2 3.79Å; K235-I337 HydrophobicContact CD-CG2 4.2Å; A239-I337 HydrophobicContact CB-CG1 4.35Å; M333-I337 PolarHBondContact O-N 3.06Å; I334-I337 WeakPolarHBondContact O-CA 2.89Å; I334-I337 WeakPolarHBondContact O-CB 3.42Å; I334-I337 PolarHBondContact O-N 2.98Å; S335-I337 VanDerWaalsContact C-N 3.3Å; S335-I337 PolarHBondContact O-N 3.18Å; I337-T340 PolarHBondContact O-OG1 2.93Å
338	L	97	Very high	95.1	Very high	59 Å²	59	16.3 Å²	16.3	31%	0.309	9%	0.085	S	C	.	.	H	α-helix	trans	-80.4	-29.9	-173	-62.2	179.9	0	0	0	112.8	E225 V226 I334 S335 M369	E225-L338 HydrophobicContact CB-CD1 4.13Å; E225-L338 HydrophobicContact CB-CD2 4.3Å; V226-L338 HydrophobicContact CG1-CD2 4.12Å; V226-L338 HydrophobicContact CG1-CG 4.36Å; I334-L338 HydrophobicContact CG2-CD1 3.85Å; I334-L338 HydrophobicContact CG2-CG 4.15Å; I334-L338 PolarHBondContact O-N 2.87Å; S335-L338 PolarHBondContact O-N 2.67Å; L338-M369 HydrophobicContact CD1-CE 4.21Å; L338-M369 HydrophobicContact CD1-SD 4.01Å
339	Y	95.9	Very high	94.8	Very high	54 Å²	54	18.7 Å²	18.7	21%	0.212	10%	0.102	C	C	.	.	S	Bend	trans	-129.6	45.8	-173.8	-50.1	-70.4	0	0	0	111.4	S335 D341 K342 V343 T368 M369 E372	S335-Y339 WeakPolarHBondContact O-CB 2.91Å; S335-Y339 PolarHBondContact O-N 3.27Å; Y339-D341 PolarHBondContact O-N 2.98Å; Y339-K342 PolarHBondContact O-N 2.72Å; Y339-K342 VanDerWaalsContact O-N 3.08Å; Y339-V343 PolarHBondContact O-N 2.98Å; Y339-T368 HydrophobicContact CD1-CG2 4.16Å; Y339-T368 HydrophobicContact CD2-CG2 3.57Å; Y339-T368 HydrophobicContact CE1-CG2 4.46Å; Y339-T368 HydrophobicContact CE2-CG2 3.9Å; Y339-T368 HydrophobicContact CG-CG2 3.73Å; Y339-M369 HydrophobicContact CD2-SD 4.39Å; Y339-M369 HydrophobicContact CE2-SD 3.84Å; Y339-E372 HydrophobicContact CE1-CB 3.91Å; Y339-E372 HydrophobicContact CE1-CG 3.92Å; Y339-E372 HydrophobicContact CE2-CB 4.26Å; Y339-E372 VanDerWaalsContact CZ-CB 3.47Å; Y339-E372 WeakPolarHBondContact OH-CB 3.49Å
340	T	95.7	Very high	94.5	Very high	25 Å²	25	21.4 Å²	21.4	15%	0.153	11%	0.114	C	C	.	.	H	α-helix	trans	-51	-53.3	-171.6	-44.2	0	0	0	0	113.6	A239 I240 R336 I337 K342 V343 A344	A239-T340 VanDerWaalsContact C-CG2 3.45Å; A239-T340 HydrophobicContact CB-CG2 4.23Å; I240-T340 WeakPolarHBondContact O-CG2 3.21Å; R336-T340 WeakPolarHBondContact O-CA 3.29Å; R336-T340 WeakPolarHBondContact O-CB 3.42Å; R336-T340 PolarHBondContact O-N 2.92Å; R336-T340 PolarHBondContact O-OG1 3.31Å; I337-T340 PolarHBondContact O-OG1 2.93Å; T340-K342 PolarHBondContact O-N 3.48Å; T340-V343 PolarHBondContact O-N 3.12Å; T340-A344 HydrophobicContact CG2-CB 4.41Å; T340-A344 WeakPolarHBondContact O-CA 3.29Å; T340-A344 WeakPolarHBondContact O-CB 3.26Å; T340-A344 PolarHBondContact O-N 2.85Å
341	D	93.8	Very high	94.2	Very high	75 Å²	75	21.4 Å²	21.4	40%	0.401	11%	0.114	S	C	.	.	H	α-helix	trans	-63.3	-28.9	-177.1	-63.8	-39	0	0	0	112.8	S242 Y339 C345	S242-D341 VanDerWaalsContact CB-OD1 3.31Å; S242-D341 WeakPolarHBondContact CB-OD1 3.45Å; S242-D341 PolarHBondContact N-OD1 3.48Å; S242-D341 PolarHBondContact OG-OD1 3.06Å; S242-D341 PolarHBondContact OG-OD2 2.98Å; Y339-D341 PolarHBondContact O-N 2.98Å; D341-C345 WeakPolarHBondContact O-CB 3.45Å
342	K	91.8	Very high	93.7	Very high	33 Å²	33	24.9 Å²	24.9	14%	0.143	14%	0.136	C	C	.	.	H	α-helix	trans	-83.9	-46.2	179.9	-171.5	-175.7	-178.3	-171.2	0	112	Y339 T340 H354 C361 T368	Y339-K342 PolarHBondContact O-N 2.72Å; Y339-K342 VanDerWaalsContact O-N 3.08Å; T340-K342 PolarHBondContact O-N 3.48Å; K342-H354 HydrophobicContact CG-CB 3.98Å; K342-C361 WeakPolarHBondContact O-CB 3.35Å; K342-T368 HydrophobicContact CD-CG2 4.2Å; K342-T368 PolarHBondContact NZ-OG1 3.27Å
343	V	93.6	Very high	93.3	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-87.5	-38.4	-170	173.7	0	0	0	0	111.7	A92 R336 Y339 T340 T362 A365	A92-V343 HydrophobicContact CB-CG1 3.93Å; R336-V343 HydrophobicContact CB-CG1 4.26Å; Y339-V343 PolarHBondContact O-N 2.98Å; T340-V343 PolarHBondContact O-N 3.12Å; V343-T362 WeakPolarHBondContact O-CG2 3.39Å; V343-T362 PolarHBondContact O-N 2.62Å; V343-A365 HydrophobicContact CG1-CB 3.96Å
344	A	93.5	Very high	92.7	Very high	6 Å²	6	35 Å²	35	5%	0.05	18%	0.18	C	C	.	.	S	Bend	trans	-100.8	20.3	-179.4	0	0	0	0	0	112.7	P241 R336 T340	P241-A344 WeakPolarHBondContact CG-O 3.31Å; R336-A344 HydrophobicContact CG-CB 4.12Å; T340-A344 HydrophobicContact CG2-CB 4.41Å; T340-A344 WeakPolarHBondContact O-CA 3.29Å; T340-A344 WeakPolarHBondContact O-CB 3.26Å; T340-A344 PolarHBondContact O-N 2.85Å
345	C	91.8	Very high	91.9	Very high	9 Å²	9	35.2 Å²	35.2	6%	0.061	18%	0.182	C	C	.	.			trans	-54.3	142.1	174.1	75.7	0	0	0	0	110.6	D341 C351 C361	D341-C345 WeakPolarHBondContact O-CB 3.45Å; C345-C351 HydrophobicContact CB-CB 4.23Å; C345-C351 WeakPolarHBondContact CB-SG 3.41Å; C345-C351 PolarHBondContact O-SG 3.45Å; C345-C351 WeakPolarHBondContact SG-CA 3.49Å; C345-C351 WeakPolarHBondContact SG-CB 3.4Å; C345-C351 CovalentContact SG-SG 2.05Å; C345-C351 PolarHBondContact SG-SG 2.89Å; C345-C361 PolarHBondContact SG-SG 3.16Å
346	V	89.4	Confident	91.1	Very high	17 Å²	17	37.3 Å²	37.3	10%	0.103	20%	0.204	C	C	.	.			trans	-131.1	-16.9	178	-67.7	0	0	0	0	113.9	I251 Y256	I251-V346 HydrophobicContact CB-CG2 4.46Å; I251-V346 HydrophobicContact CG1-CG2 4.43Å; I251-V346 HydrophobicContact CG2-CB 4.19Å; I251-V346 HydrophobicContact CG2-CG2 4.26Å; Y256-V346 HydrophobicContact CD1-CG2 4.25Å
347	V	90.8	Very high	90.3	Very high	3 Å²	3	39 Å²	39	2%	0.018	22%	0.215	C	C	.	.	S	Bend	trans	-83.8	127	175.5	178.5	0	0	0	0	108.9	V243 S349 E350 C351	V243-V347 HydrophobicContact CG1-CB 4.5Å; V243-V347 HydrophobicContact CG1-CG2 4.02Å; V347-S349 PolarHBondContact O-N 3.32Å; V347-E350 HydrophobicContact CB-CB 4.43Å; V347-E350 HydrophobicContact CB-CG 4.5Å; V347-E350 PolarHBondContact O-N 2.93Å; V347-C351 PolarHBondContact O-N 2.87Å
348	P	89.6	Confident	89.6	Confident	23 Å²	23	41.8 Å²	41.8	15%	0.149	23%	0.23	C	C	.	.	H	α-helix	trans	-53.4	-47.7	-174.6	-30.3	36.9	0	0	0	114.1	L249 E350 C351 V352 D358 L512	L249-P348 HydrophobicContact CD1-CG 4.31Å; P348-E350 PolarHBondContact O-N 3.08Å; P348-C351 PolarHBondContact O-N 3.03Å; P348-V352 WeakPolarHBondContact O-CB 3.04Å; P348-V352 VanDerWaalsContact O-CG2 3.28Å; P348-V352 WeakPolarHBondContact O-CG2 3.43Å; P348-V352 PolarHBondContact O-N 3.35Å; P348-D358 HydrophobicContact CB-CB 4.16Å; P348-L512 HydrophobicContact CG-CD1 3.85Å; P348-L512 HydrophobicContact CG-CD2 3.51Å; P348-L512 HydrophobicContact CG-CG 4.34Å
349	S	90.6	Very high	88.7	Confident	51 Å²	51	41.4 Å²	41.4	36%	0.357	23%	0.23	S	C	.	.	H	α-helix	trans	-60.4	-41.2	180	52.2	0	0	0	0	113.2	D247 V347 K353	D247-S349 VanDerWaalsContact CG-OG 3.24Å; D247-S349 WeakPolarHBondContact OD1-CB 3.15Å; D247-S349 PolarHBondContact OD1-OG 3.08Å; D247-S349 VanDerWaalsContact OD2-CB 3.31Å; D247-S349 WeakPolarHBondContact OD2-CB 3.28Å; D247-S349 PolarHBondContact OD2-N 3.34Å; D247-S349 PolarHBondContact OD2-OG 3.29Å; V347-S349 PolarHBondContact O-N 3.32Å; S349-K353 WeakPolarHBondContact O-CB 3.12Å; S349-K353 PolarHBondContact O-N 2.82Å; S349-K353 VanDerWaalsContact O-N 3.11Å
350	E	91.1	Very high	88.2	Confident	57 Å²	57	39.4 Å²	39.4	27%	0.266	23%	0.226	S	C	.	.	H	α-helix	trans	-70.4	-40.2	175.8	-69.2	-56.7	141	0	0	112.2	V243 V347 P348 K353 H354	V243-E350 HydrophobicContact CB-CG 4.43Å; V243-E350 HydrophobicContact CG1-CG 4.13Å; V347-E350 HydrophobicContact CB-CB 4.43Å; V347-E350 HydrophobicContact CB-CG 4.5Å; V347-E350 PolarHBondContact O-N 2.93Å; P348-E350 PolarHBondContact O-N 3.08Å; E350-K353 WeakPolarHBondContact O-CB 3.39Å; E350-K353 PolarHBondContact O-N 3.3Å; E350-K353 IonicContact OE2-NZ 3.76Å; E350-H354 PolarHBondContact O-CD2 3.11Å; E350-H354 PolarHBondContact O-N 2.99Å; E350-H354 VanDerWaalsContact O-N 3.08Å
351	C	89.4	Confident	87.9	Confident	1 Å²	1	38.2 Å²	38.2	1%	0.007	22%	0.219	C	C	.	.	H	α-helix	trans	-64.6	-41.9	175.8	-69.5	0	0	0	0	112.3	C345 V347 P348 K353 H354 C355 V357 C361	C345-C351 HydrophobicContact CB-CB 4.23Å; C345-C351 WeakPolarHBondContact CB-SG 3.41Å; C345-C351 PolarHBondContact O-SG 3.45Å; C345-C351 WeakPolarHBondContact SG-CA 3.49Å; C345-C351 WeakPolarHBondContact SG-CB 3.4Å; C345-C351 CovalentContact SG-SG 2.05Å; C345-C351 PolarHBondContact SG-SG 2.89Å; V347-C351 PolarHBondContact O-N 2.87Å; P348-C351 PolarHBondContact O-N 3.03Å; C351-K353 VanDerWaalsContact C-N 3.28Å; C351-K353 PolarHBondContact O-N 3.09Å; C351-H354 PolarHBondContact O-N 3.48Å; C351-H354 VanDerWaalsContact O-N 3.13Å; C351-C355 PolarHBondContact O-N 3.17Å; C351-C355 PolarHBondContact O-SG 3.16Å; C351-C355 VanDerWaalsContact O-SG 3.32Å; C351-V357 CarbonylContact C-O 3.51Å; C351-V357 WeakPolarHBondContact CB-O 3.38Å; C351-C361 PolarHBondContact O-SG 3.42Å
352	V	88.4	Confident	87.8	Confident	74 Å²	74	35.6 Å²	35.6	45%	0.448	21%	0.205	S	C	.	.	H	α-helix	trans	-61.2	-39.5	175.3	171.2	0	0	0	0	110.8	P348 H354 G356 V357 D358	P348-V352 WeakPolarHBondContact O-CB 3.04Å; P348-V352 VanDerWaalsContact O-CG2 3.28Å; P348-V352 WeakPolarHBondContact O-CG2 3.43Å; P348-V352 PolarHBondContact O-N 3.35Å; V352-H354 VanDerWaalsContact C-N 3.32Å; V352-H354 PolarHBondContact O-N 3.41Å; V352-G356 WeakPolarHBondContact O-CA 3.41Å; V352-G356 PolarHBondContact O-N 3.42Å; V352-V357 PolarHBondContact N-O 2.96Å; V352-D358 HydrophobicContact CG2-CB 3.95Å
353	K	88.6	Confident	87.8	Confident	151 Å²	151	34.4 Å²	34.4	66%	0.657	20%	0.2	S	C	*	.	H	α-helix	trans	-61.2	-39.6	174.9	-179.2	-174.5	176.3	-171.9	0	112.5	S349 E350 C351	S349-K353 WeakPolarHBondContact O-CB 3.12Å; S349-K353 PolarHBondContact O-N 2.82Å; S349-K353 VanDerWaalsContact O-N 3.11Å; E350-K353 WeakPolarHBondContact O-CB 3.39Å; E350-K353 PolarHBondContact O-N 3.3Å; E350-K353 IonicContact OE2-NZ 3.76Å; C351-K353 VanDerWaalsContact C-N 3.28Å; C351-K353 PolarHBondContact O-N 3.09Å
354	H	85.9	Confident	87.6	Confident	60 Å²	60	35 Å²	35	28%	0.278	20%	0.203	S	C	.	.	H	α-helix	trans	-85.5	-39.6	-174.6	-75	-51.1	0	0	0	115	K342 E350 C351 V352	K342-H354 HydrophobicContact CG-CB 3.98Å; E350-H354 PolarHBondContact O-CD2 3.11Å; E350-H354 PolarHBondContact O-N 2.99Å; E350-H354 VanDerWaalsContact O-N 3.08Å; C351-H354 PolarHBondContact O-N 3.48Å; C351-H354 VanDerWaalsContact O-N 3.13Å; V352-H354 VanDerWaalsContact C-N 3.32Å; V352-H354 PolarHBondContact O-N 3.41Å
355	C	81.7	Confident	87.6	Confident	6 Å²	6	34.7 Å²	34.7	4%	0.041	20%	0.201	C	C	.	.	H	α-helix	trans	-127.5	-11	-176.6	59.7	0	0	0	0	114.6	K170 C351 C361 Y364	K170-C355 PolarHBondContact NZ-O 3.25Å; C351-C355 PolarHBondContact O-N 3.17Å; C351-C355 PolarHBondContact O-SG 3.16Å; C351-C355 VanDerWaalsContact O-SG 3.32Å; C355-C361 HydrophobicContact CB-CB 3.75Å; C355-C361 WeakPolarHBondContact CB-SG 3.5Å; C355-C361 WeakPolarHBondContact SG-CA 3.04Å; C355-C361 WeakPolarHBondContact SG-CB 3.16Å; C355-C361 CovalentContact SG-SG 2.03Å; C355-C361 PolarHBondContact SG-SG 2.62Å; C355-Y364 HydrophobicContact CB-CD1 3.65Å; C355-Y364 HydrophobicContact CB-CD2 3.91Å; C355-Y364 HydrophobicContact CB-CE1 3.42Å; C355-Y364 VanDerWaalsContact CB-CE1 3.42Å; C355-Y364 HydrophobicContact CB-CE2 3.7Å; C355-Y364 HydrophobicContact CB-CG 3.94Å; C355-Y364 VanDerWaalsContact CB-CZ 3.47Å; C355-Y364 PolarHBondContact O-OH 2.82Å
356	G	80.5	Confident	87.7	Confident	44 Å²	44	34.3 Å²	34.3	45%	0.454	20%	0.198	S	C	.	.	S	Bend	trans	78.2	22	-175.5	0	0	0	0	0	113.3	V352	V352-G356 WeakPolarHBondContact O-CA 3.41Å; V352-G356 PolarHBondContact O-N 3.42Å
357	V	80.2	Confident	87.8	Confident	43 Å²	43	33.5 Å²	33.5	26%	0.261	19%	0.193	S	C	.	.			trans	-135.3	138.6	179.3	-175.7	0	0	0	0	108.2	C351 V352 V359	C351-V357 CarbonylContact C-O 3.51Å; C351-V357 WeakPolarHBondContact CB-O 3.38Å; V352-V357 PolarHBondContact N-O 2.96Å; V357-V359 HydrophobicContact CG1-CG2 3.45Å; V357-V359 VanDerWaalsContact CG1-CG2 3.45Å
358	D	82.8	Confident	87.7	Confident	87 Å²	87	33.3 Å²	33.3	47%	0.465	19%	0.192	S	C	.	.	S	Bend	trans	-86.7	-23.4	-176.2	58.1	-13.8	0	0	0	113.9	P348 V352 G360 L512	P348-D358 HydrophobicContact CB-CB 4.16Å; V352-D358 HydrophobicContact CG2-CB 3.95Å; D358-G360 PolarHBondContact O-N 3.48Å; D358-L512 WeakPolarHBondContact O-CD1 2.93Å
359	V	78.2	Confident	87.9	Confident	50 Å²	50	32.2 Å²	32.2	30%	0.303	19%	0.185	S	C	.	.	S	Bend	trans	-81.3	-5.7	-177.1	-64.1	0	0	0	0	115.6	V357	V357-V359 HydrophobicContact CG1-CG2 3.45Å; V357-V359 VanDerWaalsContact CG1-CG2 3.45Å
360	G	85.8	Confident	88	Confident	13 Å²	13	29.8 Å²	29.8	13%	0.134	17%	0.168	C	C	.	.			trans	126.6	155	179	0	0	0	0	0	114.3	D358	D358-G360 PolarHBondContact O-N 3.48Å
361	C	89.8	Confident	87.8	Confident	0 Å²	0	27.2 Å²	27.2	0%	0	16%	0.156	C	C	.	.			trans	-111	17.4	-172.4	-59.3	0	0	0	0	114.3	K342 C345 C351 C355 N363 Y364	K342-C361 WeakPolarHBondContact O-CB 3.35Å; C345-C361 PolarHBondContact SG-SG 3.16Å; C351-C361 PolarHBondContact O-SG 3.42Å; C355-C361 HydrophobicContact CB-CB 3.75Å; C355-C361 WeakPolarHBondContact CB-SG 3.5Å; C355-C361 WeakPolarHBondContact SG-CA 3.04Å; C355-C361 WeakPolarHBondContact SG-CB 3.16Å; C355-C361 CovalentContact SG-SG 2.03Å; C355-C361 PolarHBondContact SG-SG 2.62Å; C361-N363 VanDerWaalsContact C-N 3.29Å; C361-N363 PolarHBondContact O-N 3.03Å; C361-Y364 VanDerWaalsContact O-CB 3.27Å; C361-Y364 WeakPolarHBondContact O-CB 3.49Å; C361-Y364 PolarHBondContact O-N 3.35Å
362	T	91.7	Very high	87.8	Confident	19 Å²	19	29.8 Å²	29.8	12%	0.117	17%	0.168	C	C	.	.	G	3₁₀ helix	trans	-60.7	-36.3	-173.9	57.2	0	0	0	0	113	G89 A93 V343 Y364 A365 G450	G89-T362 WeakPolarHBondContact CA-O 3.34Å; G89-T362 WeakPolarHBondContact O-CB 3.38Å; A93-T362 HydrophobicContact CB-CG2 3.97Å; V343-T362 WeakPolarHBondContact O-CG2 3.39Å; V343-T362 PolarHBondContact O-N 2.62Å; T362-Y364 PolarHBondContact O-N 3.32Å; T362-A365 WeakPolarHBondContact O-CB 3.4Å; T362-A365 PolarHBondContact O-N 3.38Å; T362-G450 PolarHBondContact OG1-O 3Å
363	N	90.2	Very high	88	Confident	8 Å²	8	27.5 Å²	27.5	4%	0.043	15%	0.153	C	C	.	.	G	3₁₀ helix	trans	-55.9	-17.8	172.7	-74.1	-31.2	0	0	0	113.8	V85 I167 C361 A365 G450 L452	V85-N363 HydrophobicContact CG1-CB 3.6Å; V85-N363 WeakPolarHBondContact CG1-O 3.37Å; I167-N363 HydrophobicContact CD1-CB 4.14Å; C361-N363 VanDerWaalsContact C-N 3.29Å; C361-N363 PolarHBondContact O-N 3.03Å; N363-A365 VanDerWaalsContact C-N 3.3Å; N363-G450 PolarHBondContact ND2-O 3.39Å; N363-G450 VanDerWaalsContact ND2-O 3.09Å; N363-L452 PolarHBondContact OD1-N 2.92Å
364	Y	90.4	Very high	88.1	Confident	13 Å²	13	20.7 Å²	20.7	5%	0.051	12%	0.123	C	C	.	.	G	3₁₀ helix	trans	-85.8	-2	178.4	-74.3	-134	0	0	0	112.7	I167 L171 C355 C361 T362 P367 T368	I167-Y364 HydrophobicContact CB-CE2 4.38Å; I167-Y364 HydrophobicContact CD1-CD2 4.31Å; I167-Y364 HydrophobicContact CD1-CE2 3.81Å; I167-Y364 HydrophobicContact CG1-CE2 3.82Å; I167-Y364 HydrophobicContact CG2-CD2 3.92Å; I167-Y364 HydrophobicContact CG2-CE1 4.38Å; I167-Y364 HydrophobicContact CG2-CE2 3.69Å; I167-Y364 HydrophobicContact CG2-CG 4.32Å; L171-Y364 HydrophobicContact CD1-CD1 3.47Å; L171-Y364 VanDerWaalsContact CD1-CD1 3.47Å; L171-Y364 HydrophobicContact CD1-CE1 3.77Å; L171-Y364 HydrophobicContact CD1-CG 4.04Å; L171-Y364 HydrophobicContact CD2-CD1 3.69Å; L171-Y364 HydrophobicContact CD2-CE1 3.61Å; L171-Y364 HydrophobicContact CG-CD1 3.93Å; L171-Y364 HydrophobicContact CG-CE1 3.77Å; C355-Y364 HydrophobicContact CB-CD1 3.65Å; C355-Y364 HydrophobicContact CB-CD2 3.91Å; C355-Y364 HydrophobicContact CB-CE1 3.42Å; C355-Y364 VanDerWaalsContact CB-CE1 3.42Å; C355-Y364 HydrophobicContact CB-CE2 3.7Å; C355-Y364 HydrophobicContact CB-CG 3.94Å; C355-Y364 VanDerWaalsContact CB-CZ 3.47Å; C355-Y364 PolarHBondContact O-OH 2.82Å; C361-Y364 VanDerWaalsContact O-CB 3.27Å; C361-Y364 WeakPolarHBondContact O-CB 3.49Å; C361-Y364 PolarHBondContact O-N 3.35Å; T362-Y364 PolarHBondContact O-N 3.32Å; Y364-P367 WeakPolarHBondContact O-CD 3.44Å; Y364-T368 WeakPolarHBondContact O-CB 3.44Å; Y364-T368 PolarHBondContact O-N 3.33Å; Y364-T368 PolarHBondContact O-OG1 3.18Å
365	A	93.4	Very high	88.3	Confident	0 Å²	0	20.6 Å²	20.6	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-54.7	-60.2	-177.3	0	0	0	0	0	112.7	A92 S335 V343 T362 N363 T368 M369	A92-A365 HydrophobicContact CB-CB 3.95Å; S335-A365 VanDerWaalsContact OG-CA 3.27Å; S335-A365 WeakPolarHBondContact OG-CA 3.49Å; S335-A365 PolarHBondContact OG-O 2.02Å; V343-A365 HydrophobicContact CG1-CB 3.96Å; T362-A365 WeakPolarHBondContact O-CB 3.4Å; T362-A365 PolarHBondContact O-N 3.38Å; N363-A365 VanDerWaalsContact C-N 3.3Å; A365-T368 PolarHBondContact O-N 3.39Å; A365-M369 WeakPolarHBondContact O-CG 3.36Å; A365-M369 PolarHBondContact O-N 3.33Å
366	Y	93.6	Very high	88.5	Confident	0 Å²	0	26.7 Å²	26.7	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-64.9	-47.3	-177.8	-160.9	-84	0	0	0	113.6	Y84 A88 F168 L218 L327 P331 T368 M369 V370 M382 M386	Y84-Y366 AromaticContact CD1-CD1 3.76Å; Y84-Y366 HydrophobicContact CD1-CD1 3.76Å; Y84-Y366 HydrophobicContact CD1-CD2 4.05Å; Y84-Y366 AromaticContact CD1-CE1 3.32Å; Y84-Y366 HydrophobicContact CD1-CE1 3.32Å; Y84-Y366 AromaticContact CD1-CE2 3.66Å; Y84-Y366 HydrophobicContact CD1-CE2 3.66Å; Y84-Y366 HydrophobicContact CD1-CG 4.1Å; Y84-Y366 AromaticContact CD1-CZ 3.26Å; Y84-Y366 AromaticContact CE1-CE1 3.8Å; Y84-Y366 HydrophobicContact CE1-CE1 3.8Å; Y84-Y366 AromaticContact CE1-CE2 3.99Å; Y84-Y366 HydrophobicContact CE1-CE2 3.99Å; Y84-Y366 AromaticContact CE1-CZ 3.41Å; Y84-Y366 VanDerWaalsContact CE1-CZ 3.41Å; Y84-Y366 VanDerWaalsContact CE1-OH 3.24Å; Y84-Y366 WeakPolarHBondContact CE1-OH 3.43Å; Y84-Y366 HydrophobicContact CG-CD1 4.38Å; Y84-Y366 HydrophobicContact CG-CE1 4.21Å; Y84-Y366 WeakPolarHBondContact O-CB 3.37Å; A88-Y366 HydrophobicContact CB-CD2 3.96Å; A88-Y366 HydrophobicContact CB-CG 4.24Å; F168-Y366 HydrophobicContact CZ-CD1 4.18Å; L218-Y366 HydrophobicContact CD2-CD2 4.42Å; L218-Y366 HydrophobicContact CD2-CE1 3.91Å; L218-Y366 HydrophobicContact CD2-CE2 3.69Å; L218-Y366 VanDerWaalsContact CD2-CZ 3.4Å; L218-Y366 WeakPolarHBondContact CD2-OH 3.43Å; L327-Y366 VanDerWaalsContact O-CE2 3.31Å; L327-Y366 WeakPolarHBondContact O-CE2 3.32Å; P331-Y366 HydrophobicContact CB-CD2 4.32Å; P331-Y366 HydrophobicContact CB-CE2 4.17Å; Y366-T368 VanDerWaalsContact C-N 3.27Å; Y366-T368 PolarHBondContact O-N 2.82Å; Y366-M369 WeakPolarHBondContact O-CB 3.19Å; Y366-M369 PolarHBondContact O-N 3.18Å; Y366-V370 HydrophobicContact CD1-CG2 3.82Å; Y366-V370 HydrophobicContact CE1-CG2 3.54Å; Y366-V370 PolarHBondContact O-N 3.07Å; Y366-M382 HydrophobicContact CE1-CE 4.1Å; Y366-M382 WeakPolarHBondContact OH-CE 3.41Å; Y366-M386 HydrophobicContact CD1-CE 3.64Å; Y366-M386 HydrophobicContact CD1-SD 4.24Å; Y366-M386 HydrophobicContact CE1-CE 3.65Å; Y366-M386 HydrophobicContact CE1-SD 4.01Å
367	P	90.4	Very high	88.8	Confident	0 Å²	0	25.1 Å²	25.1	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-54.1	-43.3	172.8	-21	25.1	0	0	0	113.3	I167 F168 L171 Y364 M369 V370 L371	I167-P367 HydrophobicContact CG2-CG 4.08Å; F168-P367 HydrophobicContact CD1-CB 4.09Å; F168-P367 HydrophobicContact CD1-CG 4.17Å; F168-P367 HydrophobicContact CE1-CB 3.59Å; F168-P367 HydrophobicContact CE1-CG 3.58Å; F168-P367 HydrophobicContact CE2-CG 4.02Å; F168-P367 HydrophobicContact CZ-CB 3.98Å; F168-P367 HydrophobicContact CZ-CG 3.43Å; F168-P367 VanDerWaalsContact CZ-CG 3.43Å; L171-P367 HydrophobicContact CD1-CB 3.35Å; L171-P367 HydrophobicContact CD1-CG 3.92Å; Y364-P367 WeakPolarHBondContact O-CD 3.44Å; P367-M369 VanDerWaalsContact C-N 3.34Å; P367-M369 PolarHBondContact O-N 3.12Å; P367-V370 PolarHBondContact O-N 2.82Å; P367-L371 HydrophobicContact CB-CD1 4.33Å; P367-L371 WeakPolarHBondContact O-CB 3.43Å; P367-L371 VanDerWaalsContact O-CD1 3.23Å; P367-L371 WeakPolarHBondContact O-CD1 3.3Å; P367-L371 WeakPolarHBondContact O-CG 3.37Å; P367-L371 PolarHBondContact O-N 2.58Å
368	T	90.8	Very high	89.2	Confident	0 Å²	0	25.6 Å²	25.6	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-62.4	-42.6	179.6	-60.6	0	0	0	0	110.8	Y339 K342 Y364 A365 Y366 V370 L371 E372	Y339-T368 HydrophobicContact CD1-CG2 4.16Å; Y339-T368 HydrophobicContact CD2-CG2 3.57Å; Y339-T368 HydrophobicContact CE1-CG2 4.46Å; Y339-T368 HydrophobicContact CE2-CG2 3.9Å; Y339-T368 HydrophobicContact CG-CG2 3.73Å; K342-T368 HydrophobicContact CD-CG2 4.2Å; K342-T368 PolarHBondContact NZ-OG1 3.27Å; Y364-T368 WeakPolarHBondContact O-CB 3.44Å; Y364-T368 PolarHBondContact O-N 3.33Å; Y364-T368 PolarHBondContact O-OG1 3.18Å; A365-T368 PolarHBondContact O-N 3.39Å; Y366-T368 VanDerWaalsContact C-N 3.27Å; Y366-T368 PolarHBondContact O-N 2.82Å; T368-V370 PolarHBondContact O-N 2.77Å; T368-L371 PolarHBondContact O-N 3.21Å; T368-E372 HydrophobicContact CG2-CG 3.87Å; T368-E372 VanDerWaalsContact O-CB 3.26Å; T368-E372 WeakPolarHBondContact O-CB 3.32Å; T368-E372 WeakPolarHBondContact O-CG 2.92Å; T368-E372 PolarHBondContact O-N 3.28Å
369	M	92.5	Very high	89.5	Confident	0 Å²	0	22.2 Å²	22.2	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-58.4	-48.1	174.2	-72.3	-66.5	-70.1	0	0	112.4	L218 A222 I334 S335 L338 Y339 A365 Y366 P367 L371 L373	L218-M369 HydrophobicContact CD1-CB 4.32Å; L218-M369 HydrophobicContact CD2-CB 4.24Å; A222-M369 HydrophobicContact CB-CE 3.38Å; I334-M369 HydrophobicContact CB-CE 4.41Å; I334-M369 HydrophobicContact CG2-CE 3.71Å; I334-M369 HydrophobicContact CG2-SD 4.32Å; S335-M369 VanDerWaalsContact CA-SD 3.58Å; S335-M369 VanDerWaalsContact CB-CG 3.45Å; L338-M369 HydrophobicContact CD1-CE 4.21Å; L338-M369 HydrophobicContact CD1-SD 4.01Å; Y339-M369 HydrophobicContact CD2-SD 4.39Å; Y339-M369 HydrophobicContact CE2-SD 3.84Å; A365-M369 WeakPolarHBondContact O-CG 3.36Å; A365-M369 PolarHBondContact O-N 3.33Å; Y366-M369 WeakPolarHBondContact O-CB 3.19Å; Y366-M369 PolarHBondContact O-N 3.18Å; P367-M369 VanDerWaalsContact C-N 3.34Å; P367-M369 PolarHBondContact O-N 3.12Å; M369-L371 VanDerWaalsContact C-N 3.26Å; M369-L371 PolarHBondContact O-N 3.19Å; M369-L373 HydrophobicContact CE-CD2 3.53Å; M369-L373 WeakPolarHBondContact O-CB 3.13Å; M369-L373 PolarHBondContact O-N 3.02Å
370	V	92.3	Very high	89.9	Confident	0 Å²	0	19.8 Å²	19.8	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-60.1	-40.9	179.2	172.3	0	0	0	0	111.1	L218 Y366 P367 T368 M374 R379 M382 L383 M386	L218-V370 HydrophobicContact CD2-CG2 3.86Å; Y366-V370 HydrophobicContact CD1-CG2 3.82Å; Y366-V370 HydrophobicContact CE1-CG2 3.54Å; Y366-V370 PolarHBondContact O-N 3.07Å; P367-V370 PolarHBondContact O-N 2.82Å; T368-V370 PolarHBondContact O-N 2.77Å; V370-M374 HydrophobicContact CG1-SD 4.35Å; V370-M374 VanDerWaalsContact O-CB 3.3Å; V370-M374 WeakPolarHBondContact O-CB 3.47Å; V370-R379 HydrophobicContact CG1-CG 4.36Å; V370-M382 HydrophobicContact CG1-CB 3.65Å; V370-M382 HydrophobicContact CG1-CG 4.44Å; V370-M382 HydrophobicContact CG2-CB 4.48Å; V370-M382 HydrophobicContact CG2-CE 4.37Å; V370-L383 HydrophobicContact CG1-CD2 4.5Å; V370-M386 HydrophobicContact CG2-SD 4.36Å
371	L	88	Confident	90	Very high	2 Å²	2	21.2 Å²	21.2	1%	0.01	11%	0.111	C	C	.	.	H	α-helix	trans	-83.1	-33.4	-169.4	-68	160.9	0	0	0	113.4	L19 I23 L171 P367 T368 M369 R379 L383	L19-L371 HydrophobicContact CD2-CB 3.3Å; L19-L371 HydrophobicContact CD2-CD1 3.15Å; L19-L371 HydrophobicContact CD2-CD2 4.3Å; L19-L371 HydrophobicContact CD2-CG 3.67Å; L19-L371 HydrophobicContact CG-CB 4.21Å; I23-L371 HydrophobicContact CD1-CD2 3.62Å; I23-L371 HydrophobicContact CG1-CD2 4.29Å; L171-L371 HydrophobicContact CB-CD1 3.8Å; P367-L371 HydrophobicContact CB-CD1 4.33Å; P367-L371 WeakPolarHBondContact O-CB 3.43Å; P367-L371 VanDerWaalsContact O-CD1 3.23Å; P367-L371 WeakPolarHBondContact O-CD1 3.3Å; P367-L371 WeakPolarHBondContact O-CG 3.37Å; P367-L371 PolarHBondContact O-N 2.58Å; T368-L371 PolarHBondContact O-N 3.21Å; M369-L371 VanDerWaalsContact C-N 3.26Å; M369-L371 PolarHBondContact O-N 3.19Å; L371-R379 HydrophobicContact CD2-CG 4.27Å; L371-R379 PolarHBondContact O-NH1 3.21Å; L371-L383 HydrophobicContact CD2-CD1 4.02Å; L371-L383 HydrophobicContact CD2-CD2 3.98Å; L371-L383 HydrophobicContact CD2-CG 4.43Å
372	E	89.3	Confident	90	Very high	56 Å²	56	21.3 Å²	21.3	26%	0.262	11%	0.112	S	C	.	.	H	α-helix	trans	-94	-34.6	-177.4	-64.6	-71.1	160.7	0	0	113	L19 R22 Y339 T368	L19-E372 WeakPolarHBondContact CD1-OE1 3.45Å; R22-E372 IonicContact CZ-OE1 3.67Å; R22-E372 IonicContact CZ-OE2 3.21Å; R22-E372 IonicContact NH1-OE1 3.04Å; R22-E372 IonicContact NH1-OE2 2.64Å; R22-E372 PolarHBondContact NH1-OE2 2.9Å; R22-E372 IonicContact NH2-OE1 3.67Å; R22-E372 PolarHBondContact NH2-OE1 3.17Å; R22-E372 IonicContact NH2-OE2 3.87Å; R22-E372 PolarHBondContact NH2-OE2 2.96Å; Y339-E372 HydrophobicContact CE1-CB 3.91Å; Y339-E372 HydrophobicContact CE1-CG 3.92Å; Y339-E372 HydrophobicContact CE2-CB 4.26Å; Y339-E372 VanDerWaalsContact CZ-CB 3.47Å; Y339-E372 WeakPolarHBondContact OH-CB 3.49Å; T368-E372 HydrophobicContact CG2-CG 3.87Å; T368-E372 VanDerWaalsContact O-CB 3.26Å; T368-E372 WeakPolarHBondContact O-CB 3.32Å; T368-E372 WeakPolarHBondContact O-CG 2.92Å; T368-E372 PolarHBondContact O-N 3.28Å
373	L	91.3	Very high	89.7	Confident	25 Å²	25	20.7 Å²	20.7	13%	0.131	11%	0.107	C	C	.	.	H	α-helix	trans	-97.5	-31	-172.1	-172.8	56	0	0	0	114	L218 F221 A222 E225 M369	L218-L373 HydrophobicContact CD1-CD2 4.46Å; F221-L373 HydrophobicContact CB-CD2 3.87Å; F221-L373 HydrophobicContact CB-CG 3.99Å; A222-L373 HydrophobicContact CB-CD2 4.22Å; E225-L373 HydrophobicContact CG-CD1 3.38Å; E225-L373 HydrophobicContact CG-CD2 4.19Å; E225-L373 HydrophobicContact CG-CG 4.42Å; M369-L373 HydrophobicContact CE-CD2 3.53Å; M369-L373 WeakPolarHBondContact O-CB 3.13Å; M369-L373 PolarHBondContact O-N 3.02Å
374	M	90.6	Very high	89.5	Confident	9 Å²	9	20.3 Å²	20.3	4%	0.044	11%	0.105	C	C	.	.	S	Bend	trans	-77.8	140.3	-176.5	-67.2	-157.7	169.1	0	0	113	L218 V370 L378 R379 M382	L218-M374 HydrophobicContact CB-CE 3.29Å; L218-M374 HydrophobicContact CD1-CE 3.56Å; L218-M374 HydrophobicContact CD1-CG 3.9Å; L218-M374 HydrophobicContact CD2-CE 4.17Å; L218-M374 HydrophobicContact CG-CE 3.81Å; V370-M374 HydrophobicContact CG1-SD 4.35Å; V370-M374 VanDerWaalsContact O-CB 3.3Å; V370-M374 WeakPolarHBondContact O-CB 3.47Å; M374-L378 HydrophobicContact SD-CB 4.36Å; M374-R379 HydrophobicContact CB-CB 3.95Å; M374-M382 HydrophobicContact CE-CB 4.44Å; M374-M382 HydrophobicContact CE-CE 4.35Å; M374-M382 HydrophobicContact CE-CG 3.35Å; M374-M382 HydrophobicContact CE-SD 4.19Å; M374-M382 HydrophobicContact SD-CB 4Å; M374-M382 HydrophobicContact SD-CG 3.31Å; M374-M382 WeakPolarHBondContact SD-CG 3.29Å
375	P	90.1	Very high	89.3	Confident	57 Å²	57	19.7 Å²	19.7	37%	0.37	10%	0.103	S	C	.	.	P	Polyproline II helix	trans	-69.6	163.6	173.6	31.7	-36	0	0	0	111.6	F221 L378 R379	F221-P375 HydrophobicContact CZ-CG 4.34Å; P375-L378 HydrophobicContact CG-CB 4.21Å; P375-L378 HydrophobicContact CG-CD1 3.82Å; P375-L378 HydrophobicContact CG-CG 4.36Å; P375-L378 PolarHBondContact O-N 3.29Å; P375-R379 PolarHBondContact O-N 3.44Å
376	Q	87.6	Confident	89	Confident	134 Å²	134	19.8 Å²	19.8	63%	0.626	10%	0.104	S	C	*	.	T	Hydrogen-bonded Turn	trans	-55.4	143.6	175.7	-59.6	176.2	13	0	0	111	L378	Q376-L378 VanDerWaalsContact C-N 3.28Å; Q376-L378 PolarHBondContact O-N 3.3Å
377	G	85.9	Confident	88.6	Confident	12 Å²	12	21.3 Å²	21.3	12%	0.124	11%	0.112	C	C	.	.	T	Hydrogen-bonded Turn	trans	85.3	-55.1	-171.8	0	0	0	0	0	112.7	D28 G380 L381	D28-G377 WeakPolarHBondContact OD1-CA 3.46Å; D28-G377 PolarHBondContact OD1-N 2.86Å; G377-G380 PolarHBondContact O-N 2.72Å; G377-L381 PolarHBondContact O-N 3.46Å
378	L	87.9	Confident	88.3	Confident	53 Å²	53	21.6 Å²	21.6	28%	0.277	11%	0.114	S	C	.	.	H	α-helix	trans	-68.6	-37.6	178.1	-75.5	-179.4	0	0	0	112.2	I217 F221 M374 P375 Q376 L381 M382	I217-L378 HydrophobicContact CD1-CD2 4.27Å; I217-L378 HydrophobicContact CG2-CD1 3.88Å; F221-L378 HydrophobicContact CE2-CD1 4.38Å; M374-L378 HydrophobicContact SD-CB 4.36Å; P375-L378 HydrophobicContact CG-CB 4.21Å; P375-L378 HydrophobicContact CG-CD1 3.82Å; P375-L378 HydrophobicContact CG-CG 4.36Å; P375-L378 PolarHBondContact O-N 3.29Å; Q376-L378 VanDerWaalsContact C-N 3.28Å; Q376-L378 PolarHBondContact O-N 3.3Å; L378-L381 HydrophobicContact CD2-CD2 4.35Å; L378-L381 WeakPolarHBondContact O-CB 3.47Å; L378-L381 PolarHBondContact O-N 2.8Å; L378-M382 PolarHBondContact O-N 3.5Å
379	R	89.3	Confident	88.1	Confident	15 Å²	15	21.6 Å²	21.6	6%	0.057	11%	0.114	C	C	.	.	H	α-helix	trans	-58.5	-50.5	171.3	-177.7	176.3	60.1	-162.5	-7.2	111.2	R22 N25 D28 V370 L371 M374 P375 L381 M382 L383	R22-R379 VanDerWaalsContact CB-NH1 3.31Å; R22-R379 PolarHBondContact O-NH2 3.2Å; N25-R379 PolarHBondContact ND2-NH2 3.33Å; D28-R379 IonicContact OD2-CZ 2.91Å; D28-R379 VanDerWaalsContact OD2-CZ 3.27Å; D28-R379 IonicContact OD2-NE 3.46Å; D28-R379 PolarHBondContact OD2-NE 3.34Å; D28-R379 IonicContact OD2-NH2 3.43Å; D28-R379 PolarHBondContact OD2-NH2 3.45Å; V370-R379 HydrophobicContact CG1-CG 4.36Å; L371-R379 HydrophobicContact CD2-CG 4.27Å; L371-R379 PolarHBondContact O-NH1 3.21Å; M374-R379 HydrophobicContact CB-CB 3.95Å; P375-R379 PolarHBondContact O-N 3.44Å; R379-L381 VanDerWaalsContact C-N 3.3Å; R379-L381 PolarHBondContact O-N 3Å; R379-M382 PolarHBondContact O-N 3.17Å; R379-L383 HydrophobicContact CG-CD1 4.1Å; R379-L383 VanDerWaalsContact O-CG 3.3Å; R379-L383 WeakPolarHBondContact O-CG 3.36Å; R379-L383 PolarHBondContact O-N 3.15Å
380	G	86.5	Confident	87.8	Confident	0 Å²	0	21.7 Å²	21.7	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-57.7	-40.9	175.4	0	0	0	0	0	112.7	D28 I32 G377 L383 S384	D28-G380 WeakPolarHBondContact OD1-CA 3.49Å; D28-G380 PolarHBondContact OD1-N 2.95Å; I32-G380 WeakPolarHBondContact CG1-O 3.35Å; G377-G380 PolarHBondContact O-N 2.72Å; G380-L383 PolarHBondContact O-N 2.68Å; G380-S384 PolarHBondContact O-N 3.11Å; G380-S384 PolarHBondContact O-OG 2.94Å
381	L	88.4	Confident	87.4	Confident	42 Å²	42	22.6 Å²	22.6	22%	0.22	12%	0.119	C	C	.	.	H	α-helix	trans	-58.7	-51	174.2	-175	63.4	0	0	0	111.4	V31 Y35 I210 G377 L378 R379 L383 S384 V385	V31-L381 HydrophobicContact CG1-CB 3.73Å; V31-L381 HydrophobicContact CG1-CD1 3.96Å; V31-L381 HydrophobicContact CG1-CG 4.46Å; Y35-L381 HydrophobicContact CD2-CD1 4.22Å; I210-L381 HydrophobicContact CG2-CD1 3.86Å; I210-L381 HydrophobicContact CG2-CD2 4.33Å; I210-L381 HydrophobicContact CG2-CG 4.17Å; G377-L381 PolarHBondContact O-N 3.46Å; L378-L381 HydrophobicContact CD2-CD2 4.35Å; L378-L381 WeakPolarHBondContact O-CB 3.47Å; L378-L381 PolarHBondContact O-N 2.8Å; R379-L381 VanDerWaalsContact C-N 3.3Å; R379-L381 PolarHBondContact O-N 3Å; L381-L383 PolarHBondContact O-N 3.32Å; L381-S384 WeakPolarHBondContact O-CB 3.43Å; L381-S384 PolarHBondContact O-N 3.45Å; L381-V385 WeakPolarHBondContact O-CG2 3.03Å; L381-V385 PolarHBondContact O-N 3.26Å
382	M	89.2	Confident	87.2	Confident	2 Å²	2	22.8 Å²	22.8	1%	0.01	12%	0.12	C	C	.	.	H	α-helix	trans	-61.1	-44.8	179.2	-79.6	-57.6	-75	0	0	112	G214 Y366 V370 M374 L378 R379 S384 V385 M386	G214-M382 WeakPolarHBondContact CA-SD 3.46Å; Y366-M382 HydrophobicContact CE1-CE 4.1Å; Y366-M382 WeakPolarHBondContact OH-CE 3.41Å; V370-M382 HydrophobicContact CG1-CB 3.65Å; V370-M382 HydrophobicContact CG1-CG 4.44Å; V370-M382 HydrophobicContact CG2-CB 4.48Å; V370-M382 HydrophobicContact CG2-CE 4.37Å; M374-M382 HydrophobicContact CE-CB 4.44Å; M374-M382 HydrophobicContact CE-CE 4.35Å; M374-M382 HydrophobicContact CE-CG 3.35Å; M374-M382 HydrophobicContact CE-SD 4.19Å; M374-M382 HydrophobicContact SD-CB 4Å; M374-M382 HydrophobicContact SD-CG 3.31Å; M374-M382 WeakPolarHBondContact SD-CG 3.29Å; L378-M382 PolarHBondContact O-N 3.5Å; R379-M382 PolarHBondContact O-N 3.17Å; M382-S384 VanDerWaalsContact C-N 3.28Å; M382-S384 PolarHBondContact O-N 3.34Å; M382-V385 PolarHBondContact O-N 2.7Å; M382-V385 VanDerWaalsContact O-N 3.15Å; M382-M386 WeakPolarHBondContact O-CG 3.43Å; M382-M386 PolarHBondContact O-N 2.9Å
383	L	85.3	Confident	87.1	Confident	6 Å²	6	20.1 Å²	20.1	3%	0.031	11%	0.108	C	C	.	.	H	α-helix	trans	-57.7	-44	176.6	-69.1	171.6	0	0	0	112	I23 A172 V370 L371 R379 G380 L381 V385 M386 L387	I23-L383 HydrophobicContact CD1-CD1 3.44Å; I23-L383 VanDerWaalsContact CD1-CD1 3.44Å; I23-L383 HydrophobicContact CG1-CD1 3.72Å; I23-L383 HydrophobicContact CG2-CD1 4.41Å; A172-L383 HydrophobicContact CB-CD1 4.18Å; A172-L383 HydrophobicContact CB-CD2 3.68Å; V370-L383 HydrophobicContact CG1-CD2 4.5Å; L371-L383 HydrophobicContact CD2-CD1 4.02Å; L371-L383 HydrophobicContact CD2-CD2 3.98Å; L371-L383 HydrophobicContact CD2-CG 4.43Å; R379-L383 HydrophobicContact CG-CD1 4.1Å; R379-L383 VanDerWaalsContact O-CG 3.3Å; R379-L383 WeakPolarHBondContact O-CG 3.36Å; R379-L383 PolarHBondContact O-N 3.15Å; G380-L383 PolarHBondContact O-N 2.68Å; L381-L383 PolarHBondContact O-N 3.32Å; L383-V385 VanDerWaalsContact C-N 3.33Å; L383-V385 PolarHBondContact O-N 3.15Å; L383-M386 PolarHBondContact O-N 3.2Å; L383-L387 VanDerWaalsContact O-CG 3.28Å; L383-L387 WeakPolarHBondContact O-CG 3.05Å; L383-L387 PolarHBondContact O-N 3.41Å
384	S	86.3	Confident	86.9	Confident	0 Å²	0	19 Å²	19	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-59.4	-45.9	176.8	-48.9	0	0	0	0	111.9	I32 Y35 G380 L381 M382 M386 L387 A388	I32-S384 WeakPolarHBondContact CA-OG 3.47Å; I32-S384 WeakPolarHBondContact CG1-OG 3.11Å; Y35-S384 VanDerWaalsContact CD1-CB 3.45Å; G380-S384 PolarHBondContact O-N 3.11Å; G380-S384 PolarHBondContact O-OG 2.94Å; L381-S384 WeakPolarHBondContact O-CB 3.43Å; L381-S384 PolarHBondContact O-N 3.45Å; M382-S384 VanDerWaalsContact C-N 3.28Å; M382-S384 PolarHBondContact O-N 3.34Å; S384-M386 VanDerWaalsContact C-N 3.33Å; S384-M386 PolarHBondContact O-N 3.43Å; S384-L387 PolarHBondContact O-N 3.37Å; S384-A388 WeakPolarHBondContact O-CB 3.03Å; S384-A388 PolarHBondContact O-N 3.04Å
385	V	87.6	Confident	86.6	Confident	1 Å²	1	18.6 Å²	18.6	1%	0.006	10%	0.1	C	C	.	.	H	α-helix	trans	-65	-38.9	-178.8	171.3	0	0	0	0	111.7	Y35 I210 M211 L381 M382 L383 A388 S389	Y35-V385 HydrophobicContact CD2-CG2 4.34Å; Y35-V385 HydrophobicContact CE2-CG2 3.65Å; I210-V385 HydrophobicContact CB-CG2 4.02Å; I210-V385 HydrophobicContact CG2-CG2 3.33Å; M211-V385 HydrophobicContact CB-CG1 3.47Å; M211-V385 VanDerWaalsContact CB-CG1 3.47Å; M211-V385 HydrophobicContact CG-CG1 3.9Å; L381-V385 WeakPolarHBondContact O-CG2 3.03Å; L381-V385 PolarHBondContact O-N 3.26Å; M382-V385 PolarHBondContact O-N 2.7Å; M382-V385 VanDerWaalsContact O-N 3.15Å; L383-V385 VanDerWaalsContact C-N 3.33Å; L383-V385 PolarHBondContact O-N 3.15Å; V385-A388 PolarHBondContact O-N 3.37Å; V385-S389 WeakPolarHBondContact O-CB 3.17Å; V385-S389 PolarHBondContact O-N 3.48Å; V385-S389 PolarHBondContact O-OG 2.66Å
386	M	87.2	Confident	86.3	Confident	2 Å²	2	16 Å²	16	1%	0.01	8%	0.084	C	C	.	.	H	α-helix	trans	-73.1	-36.2	179.9	-63.2	-175.1	94.2	0	0	112.1	Y84 F168 Y366 V370 M382 L383 S384 S389 L390	Y84-M386 HydrophobicContact CD1-CE 3.77Å; Y84-M386 HydrophobicContact CD2-CE 3.9Å; Y84-M386 HydrophobicContact CG-CE 3.36Å; F168-M386 HydrophobicContact CD1-CE 4.41Å; F168-M386 HydrophobicContact CD1-SD 3.98Å; F168-M386 HydrophobicContact CD2-CE 4.27Å; F168-M386 HydrophobicContact CE1-CE 3.52Å; F168-M386 HydrophobicContact CE1-SD 3.26Å; F168-M386 WeakPolarHBondContact CE1-SD 3.44Å; F168-M386 HydrophobicContact CE2-CE 3.31Å; F168-M386 HydrophobicContact CE2-SD 4.13Å; F168-M386 HydrophobicContact CZ-CE 2.91Å; F168-M386 HydrophobicContact CZ-SD 3.41Å; F168-M386 WeakPolarHBondContact CZ-SD 3.19Å; Y366-M386 HydrophobicContact CD1-CE 3.64Å; Y366-M386 HydrophobicContact CD1-SD 4.24Å; Y366-M386 HydrophobicContact CE1-CE 3.65Å; Y366-M386 HydrophobicContact CE1-SD 4.01Å; V370-M386 HydrophobicContact CG2-SD 4.36Å; M382-M386 WeakPolarHBondContact O-CG 3.43Å; M382-M386 PolarHBondContact O-N 2.9Å; L383-M386 PolarHBondContact O-N 3.2Å; S384-M386 VanDerWaalsContact C-N 3.33Å; S384-M386 PolarHBondContact O-N 3.43Å; M386-S389 PolarHBondContact O-N 3.2Å; M386-S389 PolarHBondContact O-OG 2.91Å; M386-L390 WeakPolarHBondContact O-CB 3.1Å; M386-L390 PolarHBondContact O-N 2.97Å; M386-L390 VanDerWaalsContact O-N 3.14Å
387	L	84.1	Confident	86.4	Confident	32 Å²	32	10 Å²	10	17%	0.168	6%	0.055	C	C	.	.	H	α-helix	trans	-66.6	-41.8	171.3	-69.2	172.9	0	0	0	111.5	F36 I169 L383 S384 L390 I391	F36-L387 HydrophobicContact CZ-CB 4.05Å; I169-L387 HydrophobicContact CD1-CD2 3.94Å; I169-L387 HydrophobicContact CG1-CD2 3.4Å; I169-L387 VanDerWaalsContact CG1-CD2 3.4Å; L383-L387 VanDerWaalsContact O-CG 3.28Å; L383-L387 WeakPolarHBondContact O-CG 3.05Å; L383-L387 PolarHBondContact O-N 3.41Å; S384-L387 PolarHBondContact O-N 3.37Å; L387-L390 WeakPolarHBondContact O-CB 3.21Å; L387-I391 WeakPolarHBondContact O-CG1 3.32Å; L387-I391 PolarHBondContact O-N 3Å; L387-I391 VanDerWaalsContact O-N 3.07Å
388	A	84.1	Confident	86.4	Confident	6 Å²	6	9.4 Å²	9.4	5%	0.05	5%	0.05	C	C	.	.	H	α-helix	trans	-68.5	-36.8	175.4	0	0	0	0	0	112.8	Y35 Q207 S384 V385 L390 I391 S392	Y35-A388 HydrophobicContact CE1-CB 3.47Å; Y35-A388 VanDerWaalsContact CE1-CB 3.47Å; Y35-A388 WeakPolarHBondContact OH-CB 3.35Å; Q207-A388 PolarHBondContact OE1-O 3.47Å; S384-A388 WeakPolarHBondContact O-CB 3.03Å; S384-A388 PolarHBondContact O-N 3.04Å; V385-A388 PolarHBondContact O-N 3.37Å; A388-L390 VanDerWaalsContact C-N 3.29Å; A388-L390 PolarHBondContact O-N 3.12Å; A388-I391 PolarHBondContact O-N 3.44Å; A388-I391 VanDerWaalsContact O-N 3.12Å; A388-S392 WeakPolarHBondContact O-CB 3.49Å; A388-S392 PolarHBondContact O-N 3.24Å
389	S	86.9	Confident	86.1	Confident	0 Å²	0	7.1 Å²	7.1	0%	0	4%	0.038	C	C	.	.	H	α-helix	trans	-63.3	-39.1	176.8	73.8	0	0	0	0	112.8	V385 M386 S392 S393	V385-S389 WeakPolarHBondContact O-CB 3.17Å; V385-S389 PolarHBondContact O-N 3.48Å; V385-S389 PolarHBondContact O-OG 2.66Å; M386-S389 PolarHBondContact O-N 3.2Å; M386-S389 PolarHBondContact O-OG 2.91Å; S389-S392 PolarHBondContact O-N 2.96Å; S389-S393 WeakPolarHBondContact O-CB 3.36Å; S389-S393 PolarHBondContact O-N 3.18Å; S389-S393 PolarHBondContact O-OG 3.34Å
390	L	85.3	Confident	86	Confident	1 Å²	1	6.4 Å²	6.4	1%	0.005	4%	0.035	C	C	.	.	H	α-helix	trans	-60.6	-46.9	169.9	176.3	67.9	0	0	0	112.8	S81 D161 L184 M386 L387 A388 S392 S393 L394	S81-L390 VanDerWaalsContact OG-CD1 3.29Å; S81-L390 WeakPolarHBondContact OG-CD1 3.5Å; D161-L390 HydrophobicContact CB-CD1 4.08Å; D161-L390 WeakPolarHBondContact O-CD1 3.46Å; L184-L390 HydrophobicContact CD1-CB 4.5Å; L184-L390 HydrophobicContact CD1-CD2 3.31Å; L184-L390 HydrophobicContact CD1-CG 3.62Å; L184-L390 HydrophobicContact CD2-CD1 3.93Å; L184-L390 HydrophobicContact CD2-CD2 3.37Å; L184-L390 HydrophobicContact CD2-CG 3.64Å; L184-L390 HydrophobicContact CG-CD2 3.89Å; L184-L390 HydrophobicContact CG-CG 4.14Å; M386-L390 WeakPolarHBondContact O-CB 3.1Å; M386-L390 PolarHBondContact O-N 2.97Å; M386-L390 VanDerWaalsContact O-N 3.14Å; L387-L390 WeakPolarHBondContact O-CB 3.21Å; A388-L390 VanDerWaalsContact C-N 3.29Å; A388-L390 PolarHBondContact O-N 3.12Å; L390-S392 VanDerWaalsContact C-N 3.32Å; L390-S392 PolarHBondContact O-N 3.45Å; L390-S393 PolarHBondContact O-N 3.32Å; L390-L394 HydrophobicContact CD1-CD1 4.06Å; L390-L394 HydrophobicContact CD1-CG 4.39Å; L390-L394 HydrophobicContact CG-CD1 4.25Å; L390-L394 WeakPolarHBondContact O-CB 3.36Å; L390-L394 VanDerWaalsContact O-CG 3.31Å; L390-L394 WeakPolarHBondContact O-CG 3.46Å; L390-L394 PolarHBondContact O-N 3.11Å
391	I	84.1	Confident	86.1	Confident	20 Å²	20	6.4 Å²	6.4	10%	0.103	4%	0.035	C	C	.	.	H	α-helix	trans	-61.6	-41.8	176.5	-67.4	164.2	0	0	0	110.8	F36 L184 M187 L387 A388 T395	F36-I391 HydrophobicContact CE1-CD1 4.08Å; L184-I391 HydrophobicContact CD1-CG1 3.82Å; M187-I391 HydrophobicContact CB-CD1 4.49Å; M187-I391 HydrophobicContact CE-CD1 3.84Å; L387-I391 WeakPolarHBondContact O-CG1 3.32Å; L387-I391 PolarHBondContact O-N 3Å; L387-I391 VanDerWaalsContact O-N 3.07Å; A388-I391 PolarHBondContact O-N 3.44Å; A388-I391 VanDerWaalsContact O-N 3.12Å; I391-T395 WeakPolarHBondContact O-CB 3.12Å; I391-T395 PolarHBondContact O-N 3.38Å; I391-T395 PolarHBondContact O-OG1 3.01Å
392	S	85.1	Confident	86	Confident	5 Å²	5	4.8 Å²	4.8	4%	0.035	3%	0.027	C	C	.	.	H	α-helix	trans	-63.7	-49.1	178.4	158.5	0	0	0	0	112	D204 A388 S389 L390 T395 S396	D204-S392 WeakPolarHBondContact OD1-CB 3.44Å; D204-S392 PolarHBondContact OD1-OG 3.29Å; A388-S392 WeakPolarHBondContact O-CB 3.49Å; A388-S392 PolarHBondContact O-N 3.24Å; S389-S392 PolarHBondContact O-N 2.96Å; L390-S392 VanDerWaalsContact C-N 3.32Å; L390-S392 PolarHBondContact O-N 3.45Å; S392-T395 PolarHBondContact O-N 3.43Å; S392-S396 WeakPolarHBondContact O-CB 3.33Å; S392-S396 PolarHBondContact O-N 2.88Å; S392-S396 PolarHBondContact O-OG 2.73Å
393	S	87.4	Confident	85.7	Confident	1 Å²	1	4.7 Å²	4.7	1%	0.007	3%	0.027	C	C	.	.	H	α-helix	trans	-61.4	-47.9	177.6	-57.9	0	0	0	0	111	G80 S389 L390 T395 S396 I397	G80-S393 WeakPolarHBondContact CA-OG 3.45Å; S389-S393 WeakPolarHBondContact O-CB 3.36Å; S389-S393 PolarHBondContact O-N 3.18Å; S389-S393 PolarHBondContact O-OG 3.34Å; L390-S393 PolarHBondContact O-N 3.32Å; S393-T395 PolarHBondContact O-N 2.87Å; S393-S396 VanDerWaalsContact O-CB 3.31Å; S393-S396 WeakPolarHBondContact O-CB 3.48Å; S393-S396 PolarHBondContact O-N 3.48Å; S393-I397 WeakPolarHBondContact O-CD1 3.15Å; S393-I397 VanDerWaalsContact O-CG1 3.3Å; S393-I397 WeakPolarHBondContact O-CG1 3.29Å; S393-I397 PolarHBondContact O-N 3.35Å
394	L	86.4	Confident	85.8	Confident	0 Å²	0	4.5 Å²	4.5	0%	0	3%	0.026	C	C	.	.	H	α-helix	trans	-64.1	-41.8	178.2	-68.2	174.2	0	0	0	112.5	I158 D161 M162 L184 L185 T188 L390 S396 I397 F398	I158-L394 HydrophobicContact CB-CD2 4.48Å; I158-L394 HydrophobicContact CG2-CD2 4.07Å; D161-L394 HydrophobicContact CB-CD2 3.94Å; D161-L394 HydrophobicContact CB-CG 4.38Å; M162-L394 HydrophobicContact CG-CD1 4.41Å; M162-L394 HydrophobicContact CG-CD2 4.23Å; L184-L394 HydrophobicContact CD1-CD1 4.5Å; L184-L394 HydrophobicContact CD2-CD1 3.65Å; L184-L394 HydrophobicContact CG-CD1 3.92Å; L185-L394 HydrophobicContact CD2-CD1 4.49Å; T188-L394 HydrophobicContact CG2-CB 3.53Å; L390-L394 HydrophobicContact CD1-CD1 4.06Å; L390-L394 HydrophobicContact CD1-CG 4.39Å; L390-L394 HydrophobicContact CG-CD1 4.25Å; L390-L394 WeakPolarHBondContact O-CB 3.36Å; L390-L394 VanDerWaalsContact O-CG 3.31Å; L390-L394 WeakPolarHBondContact O-CG 3.46Å; L390-L394 PolarHBondContact O-N 3.11Å; L394-S396 VanDerWaalsContact C-N 3.26Å; L394-S396 PolarHBondContact O-N 3.27Å; L394-I397 PolarHBondContact O-N 3.27Å; L394-F398 WeakPolarHBondContact O-CB 3.48Å; L394-F398 VanDerWaalsContact O-CG 3.3Å; L394-F398 WeakPolarHBondContact O-CG 3.49Å; L394-F398 PolarHBondContact O-N 3Å
395	T	83.3	Confident	86.1	Confident	2 Å²	2	6.8 Å²	6.8	1%	0.012	4%	0.036	C	C	.	.	H	α-helix	trans	-58.5	-41.4	174.8	-62.9	0	0	0	0	111	Y191 T192 V200 I391 S392 S393 F398 N399	Y191-T395 HydrophobicContact CD1-CG2 3.89Å; Y191-T395 HydrophobicContact CE1-CG2 4.34Å; T192-T395 HydrophobicContact CG2-CG2 4.41Å; T192-T395 WeakPolarHBondContact OG1-CA 3.22Å; V200-T395 HydrophobicContact CG2-CG2 3.65Å; I391-T395 WeakPolarHBondContact O-CB 3.12Å; I391-T395 PolarHBondContact O-N 3.38Å; I391-T395 PolarHBondContact O-OG1 3.01Å; S392-T395 PolarHBondContact O-N 3.43Å; S393-T395 PolarHBondContact O-N 2.87Å; T395-F398 PolarHBondContact O-N 3.07Å; T395-N399 VanDerWaalsContact O-CB 3.28Å; T395-N399 WeakPolarHBondContact O-CB 3.5Å; T395-N399 PolarHBondContact O-N 3.12Å
396	S	85.6	Confident	86	Confident	2 Å²	2	6.8 Å²	6.8	1%	0.014	4%	0.036	C	C	.	.	H	α-helix	trans	-63.9	-43.2	178.7	-60.3	0	0	0	0	112.4	R300 S392 S393 L394 S400	R300-S396 PolarHBondContact NH2-OG 3.2Å; S392-S396 WeakPolarHBondContact O-CB 3.33Å; S392-S396 PolarHBondContact O-N 2.88Å; S392-S396 PolarHBondContact O-OG 2.73Å; S393-S396 VanDerWaalsContact O-CB 3.31Å; S393-S396 WeakPolarHBondContact O-CB 3.48Å; S393-S396 PolarHBondContact O-N 3.48Å; L394-S396 VanDerWaalsContact C-N 3.26Å; L394-S396 PolarHBondContact O-N 3.27Å; S396-S400 WeakPolarHBondContact O-CB 3.47Å; S396-S400 PolarHBondContact O-N 3.48Å; S396-S400 VanDerWaalsContact O-N 3.14Å; S396-S400 PolarHBondContact O-OG 3.14Å
397	I	87.6	Confident	85.8	Confident	7 Å²	7	8.2 Å²	8.2	4%	0.036	4%	0.043	C	C	.	.	H	α-helix	trans	-67.5	-47	177.9	-60.7	155.9	0	0	0	110	C153 L157 I158 S393 L394 N399 S400 A401	C153-I397 HydrophobicContact CB-CG2 3.99Å; L157-I397 HydrophobicContact CB-CD1 3.56Å; L157-I397 HydrophobicContact CB-CG1 4.04Å; L157-I397 HydrophobicContact CB-CG2 4.35Å; L157-I397 HydrophobicContact CD1-CG1 4.18Å; L157-I397 HydrophobicContact CD1-CG2 4.46Å; I158-I397 HydrophobicContact CD1-CG2 3.92Å; I158-I397 HydrophobicContact CG1-CB 4.36Å; I158-I397 HydrophobicContact CG1-CD1 4.43Å; I158-I397 HydrophobicContact CG1-CG2 3.61Å; S393-I397 WeakPolarHBondContact O-CD1 3.15Å; S393-I397 VanDerWaalsContact O-CG1 3.3Å; S393-I397 WeakPolarHBondContact O-CG1 3.29Å; S393-I397 PolarHBondContact O-N 3.35Å; L394-I397 PolarHBondContact O-N 3.27Å; I397-N399 PolarHBondContact O-N 3.42Å; I397-S400 PolarHBondContact O-N 3.47Å; I397-A401 WeakPolarHBondContact O-CB 3.32Å; I397-A401 PolarHBondContact O-N 3.41Å
398	F	85.9	Confident	85.7	Confident	0 Å²	0	6.7 Å²	6.7	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-63.5	-40.7	179	-70.4	-13.6	0	0	0	113	I158 L185 T188 T192 L394 T395 S400 A401 S402 V430 L433	I158-F398 HydrophobicContact CD1-CD1 4.02Å; I158-F398 HydrophobicContact CD1-CE1 3.59Å; I158-F398 HydrophobicContact CG1-CD1 4.41Å; I158-F398 HydrophobicContact CG1-CE1 3.92Å; I158-F398 HydrophobicContact CG2-CE1 4.29Å; L185-F398 HydrophobicContact CD2-CE2 4.17Å; L185-F398 HydrophobicContact CD2-CZ 3.82Å; T188-F398 HydrophobicContact CG2-CD2 3.67Å; T188-F398 HydrophobicContact CG2-CE2 3.71Å; T192-F398 HydrophobicContact CG2-CB 3.91Å; L394-F398 WeakPolarHBondContact O-CB 3.48Å; L394-F398 VanDerWaalsContact O-CG 3.3Å; L394-F398 WeakPolarHBondContact O-CG 3.49Å; L394-F398 PolarHBondContact O-N 3Å; T395-F398 PolarHBondContact O-N 3.07Å; F398-S400 VanDerWaalsContact C-N 3.33Å; F398-S400 PolarHBondContact O-N 3.45Å; F398-A401 PolarHBondContact O-N 2.8Å; F398-S402 WeakPolarHBondContact O-CB 3.21Å; F398-S402 PolarHBondContact O-N 3Å; F398-V430 HydrophobicContact CB-CG1 4Å; F398-V430 HydrophobicContact CB-CG2 4.26Å; F398-V430 HydrophobicContact CD2-CG1 3.86Å; F398-V430 HydrophobicContact CG-CG1 4.02Å; F398-L433 HydrophobicContact CD1-CD2 3.73Å; F398-L433 HydrophobicContact CE1-CD2 4.04Å; F398-L433 HydrophobicContact CE1-CG 4.38Å
399	N	83.3	Confident	85.9	Confident	5 Å²	5	7.8 Å²	7.8	3%	0.027	4%	0.04	C	C	.	.	H	α-helix	trans	-62.1	-42.7	174.7	-178.2	73.7	0	0	0	111.4	T395 I397 S402 T403	T395-N399 VanDerWaalsContact O-CB 3.28Å; T395-N399 WeakPolarHBondContact O-CB 3.5Å; T395-N399 PolarHBondContact O-N 3.12Å; I397-N399 PolarHBondContact O-N 3.42Å; N399-S402 PolarHBondContact O-N 3.07Å; N399-T403 PolarHBondContact O-N 2.99Å; N399-T403 PolarHBondContact O-OG1 3.06Å
400	S	85.9	Confident	86	Confident	1 Å²	1	10.6 Å²	10.6	1%	0.007	5%	0.051	C	C	.	.	H	α-helix	trans	-68.1	-43	178.9	-53.4	0	0	0	0	111.5	V296 S396 I397 F398 T403 L404	V296-S400 WeakPolarHBondContact CA-OG 3.27Å; V296-S400 WeakPolarHBondContact CG2-OG 3.23Å; S396-S400 WeakPolarHBondContact O-CB 3.47Å; S396-S400 PolarHBondContact O-N 3.48Å; S396-S400 VanDerWaalsContact O-N 3.14Å; S396-S400 PolarHBondContact O-OG 3.14Å; I397-S400 PolarHBondContact O-N 3.47Å; F398-S400 VanDerWaalsContact C-N 3.33Å; F398-S400 PolarHBondContact O-N 3.45Å; S400-T403 WeakPolarHBondContact O-CB 3.46Å; S400-T403 PolarHBondContact O-N 3.47Å; S400-L404 WeakPolarHBondContact O-CG 3.46Å; S400-L404 PolarHBondContact O-N 3.38Å
401	A	88.9	Confident	85.9	Confident	0 Å²	0	12.6 Å²	12.6	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-63.5	-42.2	175.8	0	0	0	0	0	112.1	L150 I397 F398 T403 L404 F405 F429 L433	L150-A401 HydrophobicContact CD2-CB 3.62Å; I397-A401 WeakPolarHBondContact O-CB 3.32Å; I397-A401 PolarHBondContact O-N 3.41Å; F398-A401 PolarHBondContact O-N 2.8Å; A401-T403 VanDerWaalsContact C-N 3.31Å; A401-T403 PolarHBondContact O-N 3.32Å; A401-L404 PolarHBondContact O-N 3.37Å; A401-F405 WeakPolarHBondContact O-CB 3.49Å; A401-F405 PolarHBondContact O-N 3.14Å; A401-F429 HydrophobicContact CB-CE1 4.28Å; A401-L433 HydrophobicContact CB-CD2 3.57Å
402	S	86.8	Confident	85.8	Confident	7 Å²	7	13.4 Å²	13.4	5%	0.049	7%	0.066	C	C	.	.	H	α-helix	trans	-58.5	-43.2	172	177.6	0	0	0	0	111.6	F398 N399 F405 A406 G426	F398-S402 WeakPolarHBondContact O-CB 3.21Å; F398-S402 PolarHBondContact O-N 3Å; N399-S402 PolarHBondContact O-N 3.07Å; S402-F405 PolarHBondContact O-N 3.32Å; S402-A406 WeakPolarHBondContact O-CB 3.27Å; S402-A406 PolarHBondContact O-N 3.42Å; S402-G426 WeakPolarHBondContact OG-CA 3.27Å; S402-G426 PolarHBondContact OG-O 2.9Å; S402-G426 VanDerWaalsContact OG-O 3.08Å
403	T	83.1	Confident	85.8	Confident	1 Å²	1	19.7 Å²	19.7	1%	0.006	10%	0.104	C	C	.	.	H	α-helix	trans	-61.1	-50.7	176.2	-50.3	0	0	0	0	111.1	F59 T127 N399 S400 A401 F405 A406 I407	F59-T403 HydrophobicContact CD1-CG2 3.86Å; F59-T403 WeakPolarHBondContact CD1-OG1 3.47Å; F59-T403 HydrophobicContact CE1-CG2 4.09Å; F59-T403 WeakPolarHBondContact CE1-OG1 3.43Å; F59-T403 HydrophobicContact CG-CG2 4.21Å; T127-T403 HydrophobicContact CG2-CG2 4.01Å; N399-T403 PolarHBondContact O-N 2.99Å; N399-T403 PolarHBondContact O-OG1 3.06Å; S400-T403 WeakPolarHBondContact O-CB 3.46Å; S400-T403 PolarHBondContact O-N 3.47Å; A401-T403 VanDerWaalsContact C-N 3.31Å; A401-T403 PolarHBondContact O-N 3.32Å; T403-F405 PolarHBondContact O-N 3.18Å; T403-A406 PolarHBondContact O-N 3.32Å; T403-I407 HydrophobicContact CG2-CD1 3.6Å; T403-I407 HydrophobicContact CG2-CG1 4.3Å; T403-I407 WeakPolarHBondContact O-CB 3.39Å; T403-I407 WeakPolarHBondContact O-CG1 3.43Å; T403-I407 PolarHBondContact O-N 2.95Å
404	L	87.4	Confident	85.6	Confident	2 Å²	2	25.9 Å²	25.9	1%	0.01	13%	0.127	C	C	.	.	I	π-helix	trans	-59.5	-45.2	179.1	-69.7	173.4	0	0	0	111.4	P129 L150 Q295 S400 A401 D408	P129-L404 HydrophobicContact CG-CD2 3.93Å; L150-L404 HydrophobicContact CD2-CB 4.32Å; L150-L404 HydrophobicContact CG-CB 4.49Å; Q295-L404 HydrophobicContact CB-CD1 4.34Å; Q295-L404 HydrophobicContact CB-CD2 4.33Å; Q295-L404 HydrophobicContact CB-CG 4.46Å; Q295-L404 HydrophobicContact CG-CD2 4.09Å; Q295-L404 HydrophobicContact CG-CG 4.15Å; S400-L404 WeakPolarHBondContact O-CG 3.46Å; S400-L404 PolarHBondContact O-N 3.38Å; A401-L404 PolarHBondContact O-N 3.37Å; L404-D408 VanDerWaalsContact CD2-OD2 3.28Å; L404-D408 WeakPolarHBondContact CD2-OD2 3.5Å; L404-D408 WeakPolarHBondContact O-CA 3.49Å; L404-D408 WeakPolarHBondContact O-CB 3.46Å; L404-D408 PolarHBondContact O-N 3.48Å
405	F	91.8	Very high	85.2	Confident	48 Å²	48	32.8 Å²	32.8	21%	0.211	16%	0.157	C	C	.	.	I	π-helix	trans	-65.5	-51	177.7	174.3	-98.9	0	0	0	111.9	A401 S402 T403 L409 Y410 A425 F429	A401-F405 WeakPolarHBondContact O-CB 3.49Å; A401-F405 PolarHBondContact O-N 3.14Å; S402-F405 PolarHBondContact O-N 3.32Å; T403-F405 PolarHBondContact O-N 3.18Å; F405-L409 HydrophobicContact CD2-CB 4.27Å; F405-L409 HydrophobicContact CD2-CD1 4.15Å; F405-L409 WeakPolarHBondContact O-CB 3.2Å; F405-L409 PolarHBondContact O-N 2.05Å; F405-Y410 HydrophobicContact CE1-CD2 4.1Å; F405-Y410 HydrophobicContact CZ-CD2 4.15Å; F405-Y410 PolarHBondContact O-N 3.27Å; F405-A425 HydrophobicContact CE1-CB 4.38Å; F405-F429 HydrophobicContact CB-CB 4.41Å; F405-F429 HydrophobicContact CB-CD1 3.49Å; F405-F429 VanDerWaalsContact CB-CD1 3.49Å; F405-F429 HydrophobicContact CB-CD2 4.04Å; F405-F429 HydrophobicContact CB-CE1 3.64Å; F405-F429 HydrophobicContact CB-CE2 4.18Å; F405-F429 HydrophobicContact CB-CG 3.7Å; F405-F429 HydrophobicContact CB-CZ 4Å; F405-F429 HydrophobicContact CD1-CB 3.41Å; F405-F429 VanDerWaalsContact CD1-CB 3.41Å; F405-F429 HydrophobicContact CD1-CD1 4.14Å; F405-F429 AromaticContact CD1-CD2 3.8Å; F405-F429 HydrophobicContact CD1-CD2 3.8Å; F405-F429 AromaticContact CD1-CG 3.5Å; F405-F429 HydrophobicContact CD1-CG 3.5Å; F405-F429 HydrophobicContact CD2-CD1 4.47Å; F405-F429 AromaticContact CD2-CD2 3.43Å; F405-F429 HydrophobicContact CD2-CD2 3.43Å; F405-F429 VanDerWaalsContact CD2-CD2 3.43Å; F405-F429 AromaticContact CD2-CE2 3.58Å; F405-F429 HydrophobicContact CD2-CE2 3.58Å; F405-F429 AromaticContact CD2-CG 3.92Å; F405-F429 HydrophobicContact CD2-CG 3.92Å; F405-F429 HydrophobicContact CD2-CZ 4.17Å; F405-F429 HydrophobicContact CE1-CB 3.73Å; F405-F429 HydrophobicContact CE1-CD2 4.08Å; F405-F429 HydrophobicContact CE1-CG 4.07Å; F405-F429 AromaticContact CE2-CD2 3.75Å; F405-F429 HydrophobicContact CE2-CD2 3.75Å; F405-F429 HydrophobicContact CE2-CE2 4.11Å; F405-F429 HydrophobicContact CE2-CG 4.45Å; F405-F429 HydrophobicContact CG-CB 3.9Å; F405-F429 AromaticContact CG-CD1 3.79Å; F405-F429 HydrophobicContact CG-CD1 3.79Å; F405-F429 AromaticContact CG-CD2 3.46Å; F405-F429 HydrophobicContact CG-CD2 3.46Å; F405-F429 VanDerWaalsContact CG-CD2 3.46Å; F405-F429 HydrophobicContact CG-CE1 4.17Å; F405-F429 AromaticContact CG-CE2 3.88Å; F405-F429 HydrophobicContact CG-CE2 3.88Å; F405-F429 AromaticContact CG-CG 3.41Å; F405-F429 HydrophobicContact CG-CG 3.41Å; F405-F429 VanDerWaalsContact CG-CG 3.41Å; F405-F429 HydrophobicContact CG-CZ 4.22Å; F405-F429 HydrophobicContact CZ-CB 4.46Å; F405-F429 HydrophobicContact CZ-CD2 4.06Å
406	A	86.9	Confident	84.9	Confident	0 Å²	0	40 Å²	40	0%	0	18%	0.184	C	C	.	.	I	π-helix	trans	-66.6	-43	-173.8	0	0	0	0	0	112.1	S402 T403 Y410 T411 I422	S402-A406 WeakPolarHBondContact O-CB 3.27Å; S402-A406 PolarHBondContact O-N 3.42Å; T403-A406 PolarHBondContact O-N 3.32Å; A406-Y410 WeakPolarHBondContact O-CB 3.41Å; A406-T411 WeakPolarHBondContact O-CG2 3.5Å; A406-T411 PolarHBondContact O-N 2.03Å; A406-I422 HydrophobicContact CB-CG2 3.86Å
407	I	81.6	Confident	84.5	Confident	32 Å²	32	40.9 Å²	40.9	16%	0.164	19%	0.192	C	C	.	.	I	π-helix	trans	-88.7	-39.2	-174.1	-58.5	-177.6	0	0	0	112.4	I55 F59 T127 T403 T411	I55-I407 HydrophobicContact CG2-CD1 4.4Å; F59-I407 HydrophobicContact CD2-CD1 4.3Å; F59-I407 HydrophobicContact CE2-CD1 4.36Å; T127-I407 HydrophobicContact CG2-CB 4.25Å; T127-I407 HydrophobicContact CG2-CD1 4.24Å; T127-I407 HydrophobicContact CG2-CG2 4.15Å; T403-I407 HydrophobicContact CG2-CD1 3.6Å; T403-I407 HydrophobicContact CG2-CG1 4.3Å; T403-I407 WeakPolarHBondContact O-CB 3.39Å; T403-I407 WeakPolarHBondContact O-CG1 3.43Å; T403-I407 PolarHBondContact O-N 2.95Å; I407-T411 PolarHBondContact O-OG1 3.38Å
408	D	83.4	Confident	84.1	Confident	0 Å²	0	43.3 Å²	43.3	0%	0	21%	0.209	C	C	.	.	I	π-helix	trans	-98.5	-20.3	-171.9	-56.7	-46	0	0	0	114	T127 Q142 S146 L404 K412	T127-D408 PolarHBondContact OG1-OD1 3.25Å; T127-D408 PolarHBondContact OG1-OD2 2.88Å; Q142-D408 HydrophobicContact CG-CB 4.18Å; Q142-D408 PolarHBondContact NE2-OD1 3.31Å; S146-D408 WeakPolarHBondContact OG-CB 3.29Å; S146-D408 VanDerWaalsContact OG-CG 3.3Å; S146-D408 PolarHBondContact OG-OD2 3.04Å; L404-D408 VanDerWaalsContact CD2-OD2 3.28Å; L404-D408 WeakPolarHBondContact CD2-OD2 3.5Å; L404-D408 WeakPolarHBondContact O-CA 3.49Å; L404-D408 WeakPolarHBondContact O-CB 3.46Å; L404-D408 PolarHBondContact O-N 3.48Å; D408-K412 VanDerWaalsContact O-CD 3.23Å; D408-K412 WeakPolarHBondContact O-CD 3.47Å; D408-K412 WeakPolarHBondContact O-CE 3.3Å
409	L	88.2	Confident	83.6	Confident	29 Å²	29	47.9 Å²	47.9	15%	0.152	23%	0.23	C	C	.	.	I	π-helix	trans	-116.1	-51.1	-177.1	-58.7	179	0	0	0	112.5	V143 I147 L150 F405 K412 V413	V143-L409 HydrophobicContact CB-CD2 4.48Å; V143-L409 HydrophobicContact CG1-CD2 4.07Å; V143-L409 HydrophobicContact CG2-CD2 4.46Å; I147-L409 HydrophobicContact CG1-CD1 4.35Å; I147-L409 HydrophobicContact CG1-CD2 4.28Å; L150-L409 HydrophobicContact CD1-CD1 3.71Å; F405-L409 HydrophobicContact CD2-CB 4.27Å; F405-L409 HydrophobicContact CD2-CD1 4.15Å; F405-L409 WeakPolarHBondContact O-CB 3.2Å; F405-L409 PolarHBondContact O-N 2.05Å; L409-K412 WeakPolarHBondContact O-CB 3.5Å; L409-K412 PolarHBondContact O-N 3.26Å; L409-V413 PolarHBondContact O-N 3.17Å
410	Y	88.6	Confident	83.2	Confident	59 Å²	59	50.7 Å²	50.7	23%	0.231	24%	0.243	C	C	.	.	I	π-helix	trans	-66.4	-48.2	-172.7	-173.6	-94.1	0	0	0	112.4	F405 A406 K412 V413 R414 A417 E421 A425	F405-Y410 HydrophobicContact CE1-CD2 4.1Å; F405-Y410 HydrophobicContact CZ-CD2 4.15Å; F405-Y410 PolarHBondContact O-N 3.27Å; A406-Y410 WeakPolarHBondContact O-CB 3.41Å; Y410-K412 PolarHBondContact O-N 3.29Å; Y410-V413 PolarHBondContact O-N 3.32Å; Y410-V413 VanDerWaalsContact O-N 3.15Å; Y410-R414 HydrophobicContact CD1-CB 4.39Å; Y410-R414 HydrophobicContact CE1-CB 3.97Å; Y410-R414 HydrophobicContact CE1-CG 4.27Å; Y410-R414 PolarHBondContact O-N 3.29Å; Y410-A417 HydrophobicContact CE1-CB 4.1Å; Y410-E421 HydrophobicContact CE1-CG 4.05Å; Y410-E421 PolarHBondContact OH-OE1 3.29Å; Y410-A425 HydrophobicContact CD1-CB 3.92Å; Y410-A425 HydrophobicContact CD2-CB 3.7Å; Y410-A425 HydrophobicContact CE1-CB 3.93Å; Y410-A425 HydrophobicContact CE2-CB 3.68Å; Y410-A425 HydrophobicContact CG-CB 3.82Å
411	T	82.6	Confident	83	Confident	43 Å²	43	53.2 Å²	53.2	26%	0.264	25%	0.254	S	S	.	.	H	α-helix	trans	-59	-27.2	176.2	50.8	0	0	0	0	113.2	A406 I407 R414 K415 I422	A406-T411 WeakPolarHBondContact O-CG2 3.5Å; A406-T411 PolarHBondContact O-N 2.03Å; I407-T411 PolarHBondContact O-OG1 3.38Å; T411-R414 CarbonylContact O-C 3.44Å; T411-R414 VanDerWaalsContact O-O 3.08Å; T411-K415 WeakPolarHBondContact O-CA 3.44Å; T411-K415 PolarHBondContact O-N 3Å; T411-I422 HydrophobicContact CG2-CD1 3.83Å; T411-I422 HydrophobicContact CG2-CG1 4.22Å
412	K	81.9	Confident	82.7	Confident	38 Å²	38	53.9 Å²	53.9	17%	0.165	26%	0.258	C	S	.	.	H	α-helix	trans	-73.4	-41.8	176	-64	-168	176.9	-172.4	0	112.7	E139 V143 D408 L409 Y410 R414	E139-K412 PolarHBondContact O-NZ 2.94Å; V143-K412 HydrophobicContact CG2-CD 3.75Å; D408-K412 VanDerWaalsContact O-CD 3.23Å; D408-K412 WeakPolarHBondContact O-CD 3.47Å; D408-K412 WeakPolarHBondContact O-CE 3.3Å; L409-K412 WeakPolarHBondContact O-CB 3.5Å; L409-K412 PolarHBondContact O-N 3.26Å; Y410-K412 PolarHBondContact O-N 3.29Å; K412-R414 VanDerWaalsContact C-N 3.34Å
413	V	85	Confident	82.3	Confident	136 Å²	136	54.1 Å²	54.1	82%	0.824	26%	0.258	S	S	*	.	H	α-helix	trans	-72.1	-37	175.7	-179.6	0	0	0	0	109.8	L409 Y410	L409-V413 PolarHBondContact O-N 3.17Å; Y410-V413 PolarHBondContact O-N 3.32Å; Y410-V413 VanDerWaalsContact O-N 3.15Å
414	R	84.6	Confident	82.3	Confident	132 Å²	132	57.7 Å²	57.7	50%	0.498	28%	0.277	S	S	.	.			trans	-120.4	84.2	-179	-169.1	73.7	-174.4	160.8	3.7	111.2	Y410 T411 K412 R416 A417 E421	Y410-R414 HydrophobicContact CD1-CB 4.39Å; Y410-R414 HydrophobicContact CE1-CB 3.97Å; Y410-R414 HydrophobicContact CE1-CG 4.27Å; Y410-R414 PolarHBondContact O-N 3.29Å; T411-R414 CarbonylContact O-C 3.44Å; T411-R414 VanDerWaalsContact O-O 3.08Å; K412-R414 VanDerWaalsContact C-N 3.34Å; R414-R416 VanDerWaalsContact C-N 3.33Å; R414-R416 PolarHBondContact O-N 2.89Å; R414-A417 HydrophobicContact CB-CB 4.45Å; R414-A417 HydrophobicContact CG-CB 3.97Å; R414-A417 WeakPolarHBondContact O-CB 3.39Å; R414-E421 WeakPolarHBondContact CG-OE1 3.45Å; R414-E421 IonicContact NE-OE1 3.4Å
415	K	76.4	Confident	82.3	Confident	145 Å²	145	58.1 Å²	58.1	63%	0.63	28%	0.28	S	S	*	.	S	Bend	trans	-60.4	-36.6	-176.6	-60.5	-169.1	175.1	-163.3	0	114.4	T411	T411-K415 WeakPolarHBondContact O-CA 3.44Å; T411-K415 PolarHBondContact O-N 3Å
416	R	78.1	Confident	81.9	Confident	153 Å²	153	55.8 Å²	55.8	58%	0.577	27%	0.27	S	S	*	.	S	Bend	trans	-102.6	62.5	178.9	-58.7	-171.9	-167.9	172.3	1.8	111.3	R414 D584	R414-R416 VanDerWaalsContact C-N 3.33Å; R414-R416 PolarHBondContact O-N 2.89Å; R416-D584 VanDerWaalsContact CZ-CG 3.49Å; R416-D584 IonicContact CZ-OD1 3.27Å; R416-D584 IonicContact CZ-OD2 3.74Å; R416-D584 IonicContact NE-OD1 2.77Å; R416-D584 IonicContact NE-OD2 3.71Å; R416-D584 PolarHBondContact NE-OD2 3.24Å; R416-D584 IonicContact NH2-OD1 2.79Å; R416-D584 PolarHBondContact NH2-OD1 2.54Å; R416-D584 IonicContact NH2-OD2 2.59Å; R416-D584 PolarHBondContact NH2-OD2 2.62Å
417	A	76.6	Confident	81.7	Confident	21 Å²	21	57.2 Å²	57.2	17%	0.174	28%	0.275	C	S	.	.			trans	-99.8	125.2	178	0	0	0	0	0	110.3	Y410 R414 E421 I422	Y410-A417 HydrophobicContact CE1-CB 4.1Å; R414-A417 HydrophobicContact CB-CB 4.45Å; R414-A417 HydrophobicContact CG-CB 3.97Å; R414-A417 WeakPolarHBondContact O-CB 3.39Å; A417-E421 HydrophobicContact CB-CB 4.48Å; A417-I422 HydrophobicContact CB-CD1 4.23Å; A417-I422 HydrophobicContact CB-CG1 3.78Å
418	S	79.5	Confident	81.9	Confident	58 Å²	58	60.8 Å²	60.8	41%	0.406	29%	0.294	S	S	.	.			trans	-65.6	155	172.5	69	0	0	0	0	111.1	K420 E421 I422	S418-K420 PolarHBondContact O-N 2.85Å; S418-K420 VanDerWaalsContact O-N 3.08Å; S418-E421 WeakPolarHBondContact O-CA 3.2Å; S418-E421 WeakPolarHBondContact O-CB 3.47Å; S418-E421 PolarHBondContact O-N 2.97Å; S418-E421 PolarHBondContact OG-N 3.44Å; S418-I422 PolarHBondContact O-N 2.9Å; S418-I422 VanDerWaalsContact O-N 3.1Å
419	E	75.1	Confident	82.2	Confident	95 Å²	95	62 Å²	62	44%	0.444	30%	0.299	S	S	.	.	H	α-helix	trans	-52	-37.9	177.1	-66.2	-167.8	136.8	0	0	112.5	I55 I422 L423	I55-E419 HydrophobicContact CD1-CG 4.3Å; E419-I422 PolarHBondContact O-N 3.49Å; E419-L423 WeakPolarHBondContact O-CG 3.46Å; E419-L423 PolarHBondContact O-N 3.45Å; E419-L423 VanDerWaalsContact O-N 3.09Å
420	K	74.2	Confident	82	Confident	65 Å²	65	60.7 Å²	60.7	28%	0.283	29%	0.292	S	S	.	.	H	α-helix	trans	-65.1	-40.3	177.4	-68.2	-173.3	178.8	-172.5	0	112.5	S418 L423 I424 L609	S418-K420 PolarHBondContact O-N 2.85Å; S418-K420 VanDerWaalsContact O-N 3.08Å; K420-L423 PolarHBondContact O-N 3.29Å; K420-I424 VanDerWaalsContact O-CG1 3.28Å; K420-I424 WeakPolarHBondContact O-CG1 3.43Å; K420-I424 PolarHBondContact O-N 2.87Å; K420-L609 WeakPolarHBondContact CE-O 3.47Å
421	E	83.7	Confident	81.8	Confident	53 Å²	53	62.1 Å²	62.1	25%	0.248	30%	0.303	C	S	.	.	H	α-helix	trans	-63.8	-44.5	178.3	-172.1	-177.8	159.2	0	0	110.8	Y410 R414 A417 S418 L423 I424 A425	Y410-E421 HydrophobicContact CE1-CG 4.05Å; Y410-E421 PolarHBondContact OH-OE1 3.29Å; R414-E421 WeakPolarHBondContact CG-OE1 3.45Å; R414-E421 IonicContact NE-OE1 3.4Å; A417-E421 HydrophobicContact CB-CB 4.48Å; S418-E421 WeakPolarHBondContact O-CA 3.2Å; S418-E421 WeakPolarHBondContact O-CB 3.47Å; S418-E421 PolarHBondContact O-N 2.97Å; S418-E421 PolarHBondContact OG-N 3.44Å; E421-L423 VanDerWaalsContact C-N 3.34Å; E421-L423 PolarHBondContact O-N 3.24Å; E421-I424 PolarHBondContact O-N 2.71Å; E421-A425 WeakPolarHBondContact O-CB 3.44Å; E421-A425 PolarHBondContact O-N 2.77Å
422	I	80.6	Confident	82.1	Confident	15 Å²	15	64.9 Å²	64.9	8%	0.077	32%	0.316	C	S	.	.	H	α-helix	trans	-59.7	-45	177.4	-62.3	171.6	0	0	0	110.7	A406 T411 A417 S418 E419 I424 A425 G426	A406-I422 HydrophobicContact CB-CG2 3.86Å; T411-I422 HydrophobicContact CG2-CD1 3.83Å; T411-I422 HydrophobicContact CG2-CG1 4.22Å; A417-I422 HydrophobicContact CB-CD1 4.23Å; A417-I422 HydrophobicContact CB-CG1 3.78Å; S418-I422 PolarHBondContact O-N 2.9Å; S418-I422 VanDerWaalsContact O-N 3.1Å; E419-I422 PolarHBondContact O-N 3.49Å; I422-I424 PolarHBondContact O-N 3.03Å; I422-A425 PolarHBondContact O-N 3.49Å; I422-G426 PolarHBondContact O-N 3.34Å; I422-G426 VanDerWaalsContact O-N 3.08Å
423	L	78.4	Confident	82.3	Confident	11 Å²	11	63.5 Å²	63.5	6%	0.058	31%	0.31	C	S	.	.	H	α-helix	trans	-63.4	-38.4	177	-68.8	173.9	0	0	0	112.7	F58 F59 E419 K420 E421 R427	F58-L423 HydrophobicContact CB-CD2 4.32Å; F58-L423 HydrophobicContact CD1-CD2 4.05Å; F58-L423 HydrophobicContact CG-CD2 4.14Å; F59-L423 HydrophobicContact CE2-CD2 4.2Å; F59-L423 HydrophobicContact CZ-CD2 4.49Å; E419-L423 WeakPolarHBondContact O-CG 3.46Å; E419-L423 PolarHBondContact O-N 3.45Å; E419-L423 VanDerWaalsContact O-N 3.09Å; K420-L423 PolarHBondContact O-N 3.29Å; E421-L423 VanDerWaalsContact C-N 3.34Å; E421-L423 PolarHBondContact O-N 3.24Å; L423-R427 WeakPolarHBondContact O-CG 3.34Å; L423-R427 PolarHBondContact O-N 2.83Å
424	I	83.2	Confident	82.2	Confident	77 Å²	77	57.8 Å²	57.8	40%	0.395	28%	0.276	S	S	.	.	H	α-helix	trans	-69.9	-44.3	177.4	-68.6	165.9	0	0	0	110.7	K420 E421 I422 G426 R427 I428 L609	K420-I424 VanDerWaalsContact O-CG1 3.28Å; K420-I424 WeakPolarHBondContact O-CG1 3.43Å; K420-I424 PolarHBondContact O-N 2.87Å; E421-I424 PolarHBondContact O-N 2.71Å; I422-I424 PolarHBondContact O-N 3.03Å; I424-G426 VanDerWaalsContact C-N 3.34Å; I424-G426 PolarHBondContact O-N 2.95Å; I424-R427 PolarHBondContact O-N 2.98Å; I424-R427 VanDerWaalsContact O-N 3.12Å; I424-I428 HydrophobicContact CG2-CD1 3.86Å; I424-I428 HydrophobicContact CG2-CG1 4.41Å; I424-I428 PolarHBondContact O-N 2.86Å; I424-L609 HydrophobicContact CG1-CD2 4.43Å
425	A	87.4	Confident	82.2	Confident	10 Å²	10	55.8 Å²	55.8	8%	0.083	28%	0.278	C	S	.	.	H	α-helix	trans	-58.5	-45	178.8	0	0	0	0	0	111.7	F405 Y410 E421 I422 R427 I428 F429	F405-A425 HydrophobicContact CE1-CB 4.38Å; Y410-A425 HydrophobicContact CD1-CB 3.92Å; Y410-A425 HydrophobicContact CD2-CB 3.7Å; Y410-A425 HydrophobicContact CE1-CB 3.93Å; Y410-A425 HydrophobicContact CE2-CB 3.68Å; Y410-A425 HydrophobicContact CG-CB 3.82Å; E421-A425 WeakPolarHBondContact O-CB 3.44Å; E421-A425 PolarHBondContact O-N 2.77Å; I422-A425 PolarHBondContact O-N 3.49Å; A425-R427 VanDerWaalsContact C-N 3.3Å; A425-R427 PolarHBondContact O-N 3.3Å; A425-I428 PolarHBondContact O-N 3.34Å; A425-F429 WeakPolarHBondContact O-CB 3.47Å; A425-F429 PolarHBondContact O-N 3.14Å
426	G	83.4	Confident	82.7	Confident	0 Å²	0	52 Å²	52	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-57.9	-39.8	174.9	0	0	0	0	0	113.2	S402 I422 I424 F429 V430	S402-G426 WeakPolarHBondContact OG-CA 3.27Å; S402-G426 PolarHBondContact OG-O 2.9Å; S402-G426 VanDerWaalsContact OG-O 3.08Å; I422-G426 PolarHBondContact O-N 3.34Å; I422-G426 VanDerWaalsContact O-N 3.08Å; I424-G426 VanDerWaalsContact C-N 3.34Å; I424-G426 PolarHBondContact O-N 2.95Å; G426-F429 WeakPolarHBondContact O-CB 3.45Å; G426-F429 PolarHBondContact O-N 3.45Å; G426-V430 WeakPolarHBondContact O-CG2 3.45Å; G426-V430 PolarHBondContact O-N 3.42Å
427	R	82.4	Confident	82.9	Confident	29 Å²	29	44.8 Å²	44.8	11%	0.109	24%	0.24	C	C	.	.	H	α-helix	trans	-70.1	-42	178.7	-72.1	171.4	172.4	165.8	8.6	113.5	I193 L423 I424 A425 F429 V430 L431 C607	I193-R427 HydrophobicContact CG1-CG 4.45Å; I193-R427 HydrophobicContact CG2-CG 4.44Å; I193-R427 PolarHBondContact O-NE 3.21Å; I193-R427 PolarHBondContact O-NH2 3.48Å; L423-R427 WeakPolarHBondContact O-CG 3.34Å; L423-R427 PolarHBondContact O-N 2.83Å; I424-R427 PolarHBondContact O-N 2.98Å; I424-R427 VanDerWaalsContact O-N 3.12Å; A425-R427 VanDerWaalsContact C-N 3.3Å; A425-R427 PolarHBondContact O-N 3.3Å; R427-F429 PolarHBondContact O-N 3.46Å; R427-V430 PolarHBondContact O-N 3.42Å; R427-L431 PolarHBondContact O-N 3.32Å; R427-C607 PolarHBondContact NH1-O 3.03Å; R427-C607 PolarHBondContact NH2-O 2.84Å
428	I	87.1	Confident	83.2	Confident	108 Å²	108	46.3 Å²	46.3	55%	0.554	25%	0.245	S	C	*	.	H	α-helix	trans	-61.8	-39	175.1	-66.7	171.5	0	0	0	109.7	I424 A425 V430 L431 L432	I424-I428 HydrophobicContact CG2-CD1 3.86Å; I424-I428 HydrophobicContact CG2-CG1 4.41Å; I424-I428 PolarHBondContact O-N 2.86Å; A425-I428 PolarHBondContact O-N 3.34Å; I428-V430 VanDerWaalsContact C-N 3.33Å; I428-V430 PolarHBondContact O-N 3.48Å; I428-L431 WeakPolarHBondContact O-CB 3.29Å; I428-L431 PolarHBondContact O-N 3.37Å; I428-L431 VanDerWaalsContact O-N 3.17Å; I428-L432 PolarHBondContact O-N 2.84Å; I428-L432 VanDerWaalsContact O-N 3.11Å
429	F	89.1	Confident	83.4	Confident	24 Å²	24	48.9 Å²	48.9	11%	0.105	26%	0.258	C	S	.	.	H	α-helix	trans	-62.3	-36.9	176.6	-176.6	-102.8	0	0	0	113.1	L150 A401 F405 A425 G426 R427 L431 L432 L433	L150-F429 HydrophobicContact CD1-CE1 4.41Å; L150-F429 HydrophobicContact CD1-CZ 3.88Å; L150-F429 HydrophobicContact CD2-CE1 3.7Å; L150-F429 HydrophobicContact CD2-CZ 3.85Å; L150-F429 HydrophobicContact CG-CZ 4.43Å; A401-F429 HydrophobicContact CB-CE1 4.28Å; F405-F429 HydrophobicContact CB-CB 4.41Å; F405-F429 HydrophobicContact CB-CD1 3.49Å; F405-F429 VanDerWaalsContact CB-CD1 3.49Å; F405-F429 HydrophobicContact CB-CD2 4.04Å; F405-F429 HydrophobicContact CB-CE1 3.64Å; F405-F429 HydrophobicContact CB-CE2 4.18Å; F405-F429 HydrophobicContact CB-CG 3.7Å; F405-F429 HydrophobicContact CB-CZ 4Å; F405-F429 HydrophobicContact CD1-CB 3.41Å; F405-F429 VanDerWaalsContact CD1-CB 3.41Å; F405-F429 HydrophobicContact CD1-CD1 4.14Å; F405-F429 AromaticContact CD1-CD2 3.8Å; F405-F429 HydrophobicContact CD1-CD2 3.8Å; F405-F429 AromaticContact CD1-CG 3.5Å; F405-F429 HydrophobicContact CD1-CG 3.5Å; F405-F429 HydrophobicContact CD2-CD1 4.47Å; F405-F429 AromaticContact CD2-CD2 3.43Å; F405-F429 HydrophobicContact CD2-CD2 3.43Å; F405-F429 VanDerWaalsContact CD2-CD2 3.43Å; F405-F429 AromaticContact CD2-CE2 3.58Å; F405-F429 HydrophobicContact CD2-CE2 3.58Å; F405-F429 AromaticContact CD2-CG 3.92Å; F405-F429 HydrophobicContact CD2-CG 3.92Å; F405-F429 HydrophobicContact CD2-CZ 4.17Å; F405-F429 HydrophobicContact CE1-CB 3.73Å; F405-F429 HydrophobicContact CE1-CD2 4.08Å; F405-F429 HydrophobicContact CE1-CG 4.07Å; F405-F429 AromaticContact CE2-CD2 3.75Å; F405-F429 HydrophobicContact CE2-CD2 3.75Å; F405-F429 HydrophobicContact CE2-CE2 4.11Å; F405-F429 HydrophobicContact CE2-CG 4.45Å; F405-F429 HydrophobicContact CG-CB 3.9Å; F405-F429 AromaticContact CG-CD1 3.79Å; F405-F429 HydrophobicContact CG-CD1 3.79Å; F405-F429 AromaticContact CG-CD2 3.46Å; F405-F429 HydrophobicContact CG-CD2 3.46Å; F405-F429 VanDerWaalsContact CG-CD2 3.46Å; F405-F429 HydrophobicContact CG-CE1 4.17Å; F405-F429 AromaticContact CG-CE2 3.88Å; F405-F429 HydrophobicContact CG-CE2 3.88Å; F405-F429 AromaticContact CG-CG 3.41Å; F405-F429 HydrophobicContact CG-CG 3.41Å; F405-F429 VanDerWaalsContact CG-CG 3.41Å; F405-F429 HydrophobicContact CG-CZ 4.22Å; F405-F429 HydrophobicContact CZ-CB 4.46Å; F405-F429 HydrophobicContact CZ-CD2 4.06Å; A425-F429 WeakPolarHBondContact O-CB 3.47Å; A425-F429 PolarHBondContact O-N 3.14Å; G426-F429 WeakPolarHBondContact O-CB 3.45Å; G426-F429 PolarHBondContact O-N 3.45Å; R427-F429 PolarHBondContact O-N 3.46Å; F429-L431 VanDerWaalsContact C-N 3.31Å; F429-L431 PolarHBondContact O-N 2.93Å; F429-L432 HydrophobicContact CD2-CD2 4.29Å; F429-L432 HydrophobicContact CE2-CD2 4.47Å; F429-L432 WeakPolarHBondContact O-CB 3.46Å; F429-L432 PolarHBondContact O-N 3.28Å; F429-L433 HydrophobicContact CE1-CD1 4.45Å; F429-L433 HydrophobicContact CE1-CD2 4.42Å; F429-L433 HydrophobicContact CZ-CD1 4.35Å; F429-L433 WeakPolarHBondContact O-CB 3.19Å; F429-L433 PolarHBondContact O-N 3.48Å
430	V	84.8	Confident	83.8	Confident	2 Å²	2	47.7 Å²	47.7	1%	0.012	25%	0.249	C	C	.	.	H	α-helix	trans	-60.2	-40.4	174	173.6	0	0	0	0	111.7	T192 F398 G426 R427 I428 L433 T434	T192-V430 HydrophobicContact CG2-CG1 4.49Å; T192-V430 HydrophobicContact CG2-CG2 4.45Å; F398-V430 HydrophobicContact CB-CG1 4Å; F398-V430 HydrophobicContact CB-CG2 4.26Å; F398-V430 HydrophobicContact CD2-CG1 3.86Å; F398-V430 HydrophobicContact CG-CG1 4.02Å; G426-V430 WeakPolarHBondContact O-CG2 3.45Å; G426-V430 PolarHBondContact O-N 3.42Å; R427-V430 PolarHBondContact O-N 3.42Å; I428-V430 VanDerWaalsContact C-N 3.33Å; I428-V430 PolarHBondContact O-N 3.48Å; V430-L433 PolarHBondContact O-N 2.81Å; V430-T434 WeakPolarHBondContact O-CB 3.45Å; V430-T434 PolarHBondContact O-N 2.74Å; V430-T434 PolarHBondContact O-OG1 3.2Å
431	L	84.8	Confident	84	Confident	89 Å²	89	45 Å²	45	47%	0.466	24%	0.238	S	C	.	.	H	α-helix	trans	-64.3	-42.4	175.9	-63.5	176.6	0	0	0	111.5	A189 I193 R427 I428 F429 T434 V435	A189-L431 HydrophobicContact CB-CD2 4.43Å; I193-L431 HydrophobicContact CD1-CD2 4.18Å; R427-L431 PolarHBondContact O-N 3.32Å; I428-L431 WeakPolarHBondContact O-CB 3.29Å; I428-L431 PolarHBondContact O-N 3.37Å; I428-L431 VanDerWaalsContact O-N 3.17Å; F429-L431 VanDerWaalsContact C-N 3.31Å; F429-L431 PolarHBondContact O-N 2.93Å; L431-T434 WeakPolarHBondContact O-CB 3.46Å; L431-T434 PolarHBondContact O-N 3.41Å; L431-V435 PolarHBondContact O-N 2.78Å
432	L	88.4	Confident	83.7	Confident	102 Å²	102	45.2 Å²	45.2	53%	0.534	24%	0.244	S	C	.	.	H	α-helix	trans	-61.2	-47	175.1	178.1	65.7	0	0	0	111.5	I428 F429 T434 V435 V436	I428-L432 PolarHBondContact O-N 2.84Å; I428-L432 VanDerWaalsContact O-N 3.11Å; F429-L432 HydrophobicContact CD2-CD2 4.29Å; F429-L432 HydrophobicContact CE2-CD2 4.47Å; F429-L432 WeakPolarHBondContact O-CB 3.46Å; F429-L432 PolarHBondContact O-N 3.28Å; L432-T434 VanDerWaalsContact C-N 3.27Å; L432-T434 PolarHBondContact O-N 2.84Å; L432-V435 PolarHBondContact O-N 2.61Å; L432-V436 WeakPolarHBondContact O-CG2 3.32Å; L432-V436 PolarHBondContact O-N 3.12Å; L432-V436 VanDerWaalsContact O-N 3.09Å
433	L	85.4	Confident	83.5	Confident	8 Å²	8	48 Å²	48	4%	0.042	26%	0.259	C	S	.	.	H	α-helix	trans	-60.1	-40.8	-179.8	-166.6	68.5	0	0	0	111.1	V154 I158 F398 A401 F429 V430 V435 V436 S437	V154-L433 HydrophobicContact CG2-CD1 3.38Å; V154-L433 HydrophobicContact CG2-CG 4.34Å; I158-L433 HydrophobicContact CD1-CD2 3.86Å; I158-L433 HydrophobicContact CD1-CG 4.03Å; F398-L433 HydrophobicContact CD1-CD2 3.73Å; F398-L433 HydrophobicContact CE1-CD2 4.04Å; F398-L433 HydrophobicContact CE1-CG 4.38Å; A401-L433 HydrophobicContact CB-CD2 3.57Å; F429-L433 HydrophobicContact CE1-CD1 4.45Å; F429-L433 HydrophobicContact CE1-CD2 4.42Å; F429-L433 HydrophobicContact CZ-CD1 4.35Å; F429-L433 WeakPolarHBondContact O-CB 3.19Å; F429-L433 PolarHBondContact O-N 3.48Å; V430-L433 PolarHBondContact O-N 2.81Å; L433-V435 VanDerWaalsContact C-N 3.33Å; L433-V435 PolarHBondContact O-N 3.48Å; L433-V436 PolarHBondContact O-N 3.37Å; L433-S437 WeakPolarHBondContact O-CB 3.41Å; L433-S437 PolarHBondContact O-N 2.96Å; L433-S437 PolarHBondContact O-OG 3.38Å
434	T	82.3	Confident	83.2	Confident	16 Å²	16	47.6 Å²	47.6	10%	0.098	26%	0.257	C	S	.	.	H	α-helix	trans	-56.2	-46.4	176.1	-60.3	0	0	0	0	111.5	L185 V430 L431 L432 S437 I438	L185-T434 HydrophobicContact CB-CG2 3.69Å; L185-T434 HydrophobicContact CD1-CG2 3.75Å; L185-T434 HydrophobicContact CD2-CG2 4.12Å; L185-T434 HydrophobicContact CG-CG2 4.07Å; V430-T434 WeakPolarHBondContact O-CB 3.45Å; V430-T434 PolarHBondContact O-N 2.74Å; V430-T434 PolarHBondContact O-OG1 3.2Å; L431-T434 WeakPolarHBondContact O-CB 3.46Å; L431-T434 PolarHBondContact O-N 3.41Å; L432-T434 VanDerWaalsContact C-N 3.27Å; L432-T434 PolarHBondContact O-N 2.84Å; T434-S437 PolarHBondContact O-N 3.49Å; T434-I438 WeakPolarHBondContact O-CG1 3.31Å; T434-I438 PolarHBondContact O-N 2.92Å
435	V	85.3	Confident	82.7	Confident	90 Å²	90	47.7 Å²	47.7	55%	0.545	26%	0.256	S	S	.	.	H	α-helix	trans	-65.6	-45.1	178.8	175.3	0	0	0	0	111.1	L431 L432 L433 S437 I438 V439	L431-V435 PolarHBondContact O-N 2.78Å; L432-V435 PolarHBondContact O-N 2.61Å; L433-V435 VanDerWaalsContact C-N 3.33Å; L433-V435 PolarHBondContact O-N 3.48Å; V435-S437 VanDerWaalsContact C-N 3.28Å; V435-S437 PolarHBondContact O-N 3.25Å; V435-I438 PolarHBondContact O-N 3.39Å; V435-V439 WeakPolarHBondContact O-CG2 3.08Å; V435-V439 PolarHBondContact O-N 3.17Å
436	V	87	Confident	81.8	Confident	66 Å²	66	52.9 Å²	52.9	40%	0.4	29%	0.286	S	S	.	.	H	α-helix	trans	-60.4	-40.3	178.3	174	0	0	0	0	111.1	V154 L432 L433 I438 V439 W440	V154-V436 HydrophobicContact CG1-CG1 4.16Å; L432-V436 WeakPolarHBondContact O-CG2 3.32Å; L432-V436 PolarHBondContact O-N 3.12Å; L432-V436 VanDerWaalsContact O-N 3.09Å; L433-V436 PolarHBondContact O-N 3.37Å; V436-I438 PolarHBondContact O-N 3.1Å; V436-V439 PolarHBondContact O-N 3.3Å; V436-W440 PolarHBondContact O-N 2.95Å; V436-W440 VanDerWaalsContact O-N 3.14Å
437	S	82.8	Confident	80.9	Confident	2 Å²	2	53.8 Å²	53.8	1%	0.014	29%	0.292	C	S	.	.	H	α-helix	trans	-64	-38.4	177.6	-64.5	0	0	0	0	113.3	I158 L433 T434 V435 V439 W440 V441	I158-S437 VanDerWaalsContact CG2-CB 3.5Å; I158-S437 WeakPolarHBondContact CG2-OG 3.4Å; L433-S437 WeakPolarHBondContact O-CB 3.41Å; L433-S437 PolarHBondContact O-N 2.96Å; L433-S437 PolarHBondContact O-OG 3.38Å; T434-S437 PolarHBondContact O-N 3.49Å; V435-S437 VanDerWaalsContact C-N 3.28Å; V435-S437 PolarHBondContact O-N 3.25Å; S437-V439 VanDerWaalsContact C-N 3.34Å; S437-W440 PolarHBondContact O-N 2.85Å; S437-V441 PolarHBondContact O-N 2.93Å
438	I	81.6	Confident	80.1	Confident	53 Å²	53	52.7 Å²	52.7	27%	0.272	29%	0.289	S	S	.	.	H	α-helix	trans	-62.3	-43.2	174.2	-65.6	169.3	0	0	0	110.7	M162 I181 L185 T434 V435 V436 W440 V441	M162-I438 HydrophobicContact CE-CG1 4.36Å; I181-I438 HydrophobicContact CG2-CG1 4.2Å; L185-I438 HydrophobicContact CD1-CD1 3.58Å; L185-I438 HydrophobicContact CD1-CG1 3.26Å; T434-I438 WeakPolarHBondContact O-CG1 3.31Å; T434-I438 PolarHBondContact O-N 2.92Å; V435-I438 PolarHBondContact O-N 3.39Å; V436-I438 PolarHBondContact O-N 3.1Å; I438-W440 PolarHBondContact O-N 3.37Å; I438-V441 WeakPolarHBondContact O-CB 3.14Å; I438-V441 WeakPolarHBondContact O-CG2 3.39Å; I438-V441 PolarHBondContact O-N 3.48Å
439	V	85.1	Confident	78.9	Confident	111 Å²	111	49.7 Å²	49.7	67%	0.673	27%	0.273	S	S	*	.	H	α-helix	trans	-63.9	-26.6	178.9	175.3	0	0	0	0	111.9	V435 V436 S437 P442	V435-V439 WeakPolarHBondContact O-CG2 3.08Å; V435-V439 PolarHBondContact O-N 3.17Å; V436-V439 PolarHBondContact O-N 3.3Å; S437-V439 VanDerWaalsContact C-N 3.34Å; V439-P442 WeakPolarHBondContact O-CD 3.13Å
440	W	83	Confident	77.9	Confident	70 Å²	70	48.9 Å²	48.9	27%	0.265	27%	0.272	S	S	.	.	H	α-helix	trans	-79.3	-18.9	179.5	-156.8	-98.2	0	0	0	113.9	V154 V155 V436 S437 I438 P442 L443 V444	V154-W440 HydrophobicContact CG1-CB 4.43Å; V154-W440 HydrophobicContact CG1-CG 4.4Å; V155-W440 HydrophobicContact CB-CZ2 4.21Å; V155-W440 HydrophobicContact CG1-CZ2 3.88Å; V155-W440 HydrophobicContact CG2-CD2 4.35Å; V155-W440 HydrophobicContact CG2-CH2 4.01Å; V155-W440 HydrophobicContact CG2-CZ2 3.4Å; V436-W440 PolarHBondContact O-N 2.95Å; V436-W440 VanDerWaalsContact O-N 3.14Å; S437-W440 PolarHBondContact O-N 2.85Å; I438-W440 PolarHBondContact O-N 3.37Å; W440-P442 VanDerWaalsContact C-CD 3.49Å; W440-L443 HydrophobicContact CD2-CD2 4.23Å; W440-L443 HydrophobicContact CH2-CD2 3.78Å; W440-L443 HydrophobicContact CZ2-CD2 3.32Å; W440-L443 HydrophobicContact CZ3-CD2 4.38Å; W440-L443 WeakPolarHBondContact O-CB 3.31Å; W440-L443 PolarHBondContact O-N 3.13Å; W440-L443 VanDerWaalsContact O-N 3.15Å; W440-V444 VanDerWaalsContact CD1-CG2 3.5Å; W440-V444 WeakPolarHBondContact O-CG2 3.44Å; W440-V444 PolarHBondContact O-N 3.24Å
441	V	78.3	Confident	77.7	Confident	8 Å²	8	51.2 Å²	51.2	5%	0.048	28%	0.283	C	S	.	.	H	α-helix	trans	-53.3	-45.7	-175	174.6	0	0	0	0	113.9	M162 I181 S437 I438 L443 V444 Q445	M162-V441 HydrophobicContact CE-CG2 3.78Å; I181-V441 HydrophobicContact CD1-CG1 3.9Å; I181-V441 HydrophobicContact CD1-CG2 4.01Å; S437-V441 PolarHBondContact O-N 2.93Å; I438-V441 WeakPolarHBondContact O-CB 3.14Å; I438-V441 WeakPolarHBondContact O-CG2 3.39Å; I438-V441 PolarHBondContact O-N 3.48Å; V441-L443 VanDerWaalsContact C-N 3.26Å; V441-L443 PolarHBondContact O-N 2.95Å; V441-V444 WeakPolarHBondContact O-CB 3.48Å; V441-V444 PolarHBondContact O-N 2.96Å; V441-V444 VanDerWaalsContact O-N 3.12Å; V441-Q445 HydrophobicContact CG1-CG 4.46Å; V441-Q445 PolarHBondContact O-N 3.08Å
442	P	78.1	Confident	77.6	Confident	58 Å²	58	47 Å²	47	38%	0.377	26%	0.26	S	S	.	.	H	α-helix	trans	-60.6	-35.1	-178.5	-24.2	35.1	0	0	0	113.2	V439 W440 V444 Q445 V446	V439-P442 WeakPolarHBondContact O-CD 3.13Å; W440-P442 VanDerWaalsContact C-CD 3.49Å; P442-V444 VanDerWaalsContact C-N 3.3Å; P442-V444 PolarHBondContact O-N 3.11Å; P442-Q445 PolarHBondContact O-N 2.9Å; P442-V446 PolarHBondContact O-N 2.99Å
443	L	75.6	Confident	77.6	Confident	74 Å²	74	42.3 Å²	42.3	39%	0.387	24%	0.236	S	C	.	.	H	α-helix	trans	-65.9	-38.7	179.1	-172.4	67.5	0	0	0	111.2	W440 V441 V446 S447	W440-L443 HydrophobicContact CD2-CD2 4.23Å; W440-L443 HydrophobicContact CH2-CD2 3.78Å; W440-L443 HydrophobicContact CZ2-CD2 3.32Å; W440-L443 HydrophobicContact CZ3-CD2 4.38Å; W440-L443 WeakPolarHBondContact O-CB 3.31Å; W440-L443 PolarHBondContact O-N 3.13Å; W440-L443 VanDerWaalsContact O-N 3.15Å; V441-L443 VanDerWaalsContact C-N 3.26Å; V441-L443 PolarHBondContact O-N 2.95Å; L443-V446 PolarHBondContact O-N 2.65Å; L443-S447 PolarHBondContact O-N 3.08Å; L443-S447 PolarHBondContact O-OG 3.08Å
444	V	73.1	Confident	77.8	Confident	2 Å²	2	43.2 Å²	43.2	1%	0.012	24%	0.24	C	C	.	.	H	α-helix	trans	-66.1	-39.2	-179.8	-179.8	0	0	0	0	111.2	A159 F163 W440 V441 P442 V446 S447 Q448	A159-V444 HydrophobicContact CB-CG1 4.45Å; A159-V444 HydrophobicContact CB-CG2 3.53Å; F163-V444 HydrophobicContact CB-CG1 4.38Å; W440-V444 VanDerWaalsContact CD1-CG2 3.5Å; W440-V444 WeakPolarHBondContact O-CG2 3.44Å; W440-V444 PolarHBondContact O-N 3.24Å; V441-V444 WeakPolarHBondContact O-CB 3.48Å; V441-V444 PolarHBondContact O-N 2.96Å; V441-V444 VanDerWaalsContact O-N 3.12Å; P442-V444 VanDerWaalsContact C-N 3.3Å; P442-V444 PolarHBondContact O-N 3.11Å; V444-V446 VanDerWaalsContact C-N 3.27Å; V444-V446 PolarHBondContact O-N 2.98Å; V444-S447 PolarHBondContact O-N 2.89Å; V444-S447 PolarHBondContact O-OG 2.96Å; V444-Q448 VanDerWaalsContact CG1-CD 3.45Å; V444-Q448 HydrophobicContact CG1-CG 4.2Å; V444-Q448 VanDerWaalsContact O-CG 3.26Å; V444-Q448 WeakPolarHBondContact O-CG 3.41Å; V444-Q448 PolarHBondContact O-N 3.2Å
445	Q	72.6	Confident	78	Confident	79 Å²	79	43 Å²	43	37%	0.369	24%	0.238	S	C	.	.	H	α-helix	trans	-62.3	-36	178	-66.4	-175.9	-68.1	0	0	112.3	F163 V441 P442	F163-Q445 HydrophobicContact CD2-CG 4.44Å; F163-Q445 HydrophobicContact CE2-CG 4.27Å; V441-Q445 HydrophobicContact CG1-CG 4.46Å; V441-Q445 PolarHBondContact O-N 3.08Å; P442-Q445 PolarHBondContact O-N 2.9Å
446	V	68.5	Low	78.2	Confident	119 Å²	119	39.3 Å²	39.3	72%	0.721	22%	0.215	S	C	*	.	H	α-helix	trans	-77.4	-29.7	-179.6	178.4	0	0	0	0	111.8	P442 L443 V444	P442-V446 PolarHBondContact O-N 2.99Å; L443-V446 PolarHBondContact O-N 2.65Å; V444-V446 VanDerWaalsContact C-N 3.27Å; V444-V446 PolarHBondContact O-N 2.98Å
447	S	64.3	Low	78.4	Confident	19 Å²	19	38 Å²	38	13%	0.133	21%	0.205	C	C	.	.	H	α-helix	trans	-94.1	-9.6	-168.1	61.7	0	0	0	0	116.3	L443 V444 Y455 F504	L443-S447 PolarHBondContact O-N 3.08Å; L443-S447 PolarHBondContact O-OG 3.08Å; V444-S447 PolarHBondContact O-N 2.89Å; V444-S447 PolarHBondContact O-OG 2.96Å; S447-Y455 WeakPolarHBondContact OG-CD2 3.4Å; S447-Y455 WeakPolarHBondContact OG-CE2 3.48Å; S447-F504 VanDerWaalsContact CB-CE1 3.46Å
448	Q	65	Low	78.8	Confident	7 Å²	7	38.2 Å²	38.2	3%	0.033	21%	0.206	C	C	.	.	S	Bend	trans	-87.5	-7.1	-168.3	-77.4	-179.6	-9.3	0	0	115.3	V444 G450 Q451 L452 Y455	V444-Q448 VanDerWaalsContact CG1-CD 3.45Å; V444-Q448 HydrophobicContact CG1-CG 4.2Å; V444-Q448 VanDerWaalsContact O-CG 3.26Å; V444-Q448 WeakPolarHBondContact O-CG 3.41Å; V444-Q448 PolarHBondContact O-N 3.2Å; Q448-G450 PolarHBondContact O-N 3.35Å; Q448-Q451 CarbonylContact O-C 3.54Å; Q448-Q451 PolarHBondContact O-N 2.88Å; Q448-L452 HydrophobicContact CG-CD1 4.29Å; Q448-Y455 HydrophobicContact CG-CD1 3.79Å; Q448-Y455 HydrophobicContact CG-CD2 3.94Å; Q448-Y455 HydrophobicContact CG-CE1 4.37Å; Q448-Y455 HydrophobicContact CG-CE2 4.48Å; Q448-Y455 HydrophobicContact CG-CG 3.56Å
449	N	62.7	Low	79.3	Confident	44 Å²	44	35.9 Å²	35.9	24%	0.235	19%	0.194	C	C	.	.	T	Hydrogen-bonded Turn	trans	41.4	33.1	174.9	-83.3	27.3	0	0	0	114.9	Q451 T508 P509	N449-Q451 VanDerWaalsContact C-N 3.32Å; N449-Q451 PolarHBondContact O-N 3.32Å; N449-T508 WeakPolarHBondContact ND2-CB 3.28Å; N449-T508 PolarHBondContact ND2-O 3.1Å; N449-T508 PolarHBondContact ND2-OG1 2.95Å; N449-T508 PolarHBondContact OD1-OG1 3.09Å; N449-P509 PolarHBondContact ND2-O 3.35Å
450	G	68.3	Low	79.7	Confident	7 Å²	7	30.9 Å²	30.9	7%	0.072	17%	0.165	C	C	.	.	T	Hydrogen-bonded Turn	trans	79.6	-7.6	-179	0	0	0	0	0	116.5	T362 N363 Q448	T362-G450 PolarHBondContact OG1-O 3Å; N363-G450 PolarHBondContact ND2-O 3.39Å; N363-G450 VanDerWaalsContact ND2-O 3.09Å; Q448-G450 PolarHBondContact O-N 3.35Å
451	Q	79.7	Confident	80.3	Confident	51 Å²	51	27.6 Å²	27.6	24%	0.238	15%	0.152	C	C	.	.			trans	-129.6	100.5	-179.8	-63.2	-179.8	-68.5	0	0	112.8	Q448 N449 I453 H454 Y455	Q448-Q451 CarbonylContact O-C 3.54Å; Q448-Q451 PolarHBondContact O-N 2.88Å; N449-Q451 VanDerWaalsContact C-N 3.32Å; N449-Q451 PolarHBondContact O-N 3.32Å; Q451-I453 VanDerWaalsContact C-N 3.34Å; Q451-I453 PolarHBondContact O-N 3.29Å; Q451-H454 HydrophobicContact CB-CB 4.47Å; Q451-H454 PolarHBondContact O-N 2.99Å; Q451-Y455 PolarHBondContact O-N 3.49Å
452	L	83.5	Confident	81	Confident	0 Å²	0	27.3 Å²	27.3	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-62.6	-34.7	-172.6	-177.4	59.7	0	0	0	114.3	N82 V85 S160 F163 A164 N363 Q448 T456	N82-L452 HydrophobicContact CB-CD2 4.38Å; N82-L452 WeakPolarHBondContact OD1-CD2 3.33Å; N82-L452 WeakPolarHBondContact OD1-CG 3.4Å; V85-L452 HydrophobicContact CB-CD2 4.39Å; V85-L452 HydrophobicContact CG1-CD2 4.11Å; S160-L452 VanDerWaalsContact OG-CD1 3.3Å; S160-L452 WeakPolarHBondContact OG-CD1 3.3Å; F163-L452 HydrophobicContact CD1-CD1 4.09Å; F163-L452 HydrophobicContact CD1-CD2 4.36Å; A164-L452 HydrophobicContact CB-CD2 3.82Å; N363-L452 PolarHBondContact OD1-N 2.92Å; Q448-L452 HydrophobicContact CG-CD1 4.29Å; L452-T456 PolarHBondContact O-N 2.9Å; L452-T456 VanDerWaalsContact O-N 3.08Å; L452-T456 PolarHBondContact O-OG1 3.38Å
453	I	88.1	Confident	81.8	Confident	5 Å²	5	24.7 Å²	24.7	3%	0.026	13%	0.133	C	C	.	.	H	α-helix	trans	-71.9	-42.8	-177.6	-65.6	-65.6	0	0	0	111.4	G86 L87 F101 Q451 Y455 T456 E457	G86-I453 WeakPolarHBondContact O-CG1 3.32Å; L87-I453 HydrophobicContact CD2-CD1 4.06Å; L87-I453 HydrophobicContact CD2-CG1 4.05Å; L87-I453 HydrophobicContact CD2-CG2 4.43Å; L87-I453 HydrophobicContact CG-CD1 4.13Å; L87-I453 HydrophobicContact CG-CG1 4.32Å; F101-I453 HydrophobicContact CD2-CG2 3.43Å; F101-I453 VanDerWaalsContact CD2-CG2 3.43Å; F101-I453 HydrophobicContact CE2-CG2 3.66Å; F101-I453 HydrophobicContact CG-CG2 4.05Å; F101-I453 HydrophobicContact CZ-CG2 4.45Å; Q451-I453 VanDerWaalsContact C-N 3.34Å; Q451-I453 PolarHBondContact O-N 3.29Å; I453-Y455 VanDerWaalsContact C-N 3.29Å; I453-Y455 PolarHBondContact O-N 3.48Å; I453-T456 PolarHBondContact O-N 3.1Å; I453-T456 VanDerWaalsContact O-N 3.13Å; I453-E457 HydrophobicContact CG2-CG 4.02Å; I453-E457 WeakPolarHBondContact O-CB 3.2Å; I453-E457 WeakPolarHBondContact O-CG 3.26Å; I453-E457 PolarHBondContact O-N 3.12Å
454	H	88.4	Confident	82.8	Confident	27 Å²	27	21.2 Å²	21.2	13%	0.125	12%	0.115	C	C	.	.	H	α-helix	trans	-62.3	-38.1	176.9	-73.9	-75.9	0	0	0	112	T90 Q451 S458 Y526	T90-H454 WeakPolarHBondContact CG2-NE2 3.24Å; Q451-H454 HydrophobicContact CB-CB 4.47Å; Q451-H454 PolarHBondContact O-N 2.99Å; H454-S458 WeakPolarHBondContact O-CB 3.28Å; H454-S458 PolarHBondContact O-N 3.28Å; H454-S458 PolarHBondContact O-OG 3.2Å; H454-Y526 AromaticContact ND1-CE1 3.94Å; H454-Y526 AromaticContact ND1-CZ 3.93Å; H454-Y526 PolarHBondContact ND1-OH 2.93Å
455	Y	86.6	Confident	83.9	Confident	11 Å²	11	21.1 Å²	21.1	4%	0.043	11%	0.114	C	C	.	.	H	α-helix	trans	-60.2	-47.7	171.3	167.9	-96.3	0	0	0	112.2	V155 S447 Q448 Q451 I453 S458 I459 F504	V155-Y455 PolarHBondContact O-OH 3.48Å; V155-Y455 VanDerWaalsContact O-OH 3.13Å; S447-Y455 WeakPolarHBondContact OG-CD2 3.4Å; S447-Y455 WeakPolarHBondContact OG-CE2 3.48Å; Q448-Y455 HydrophobicContact CG-CD1 3.79Å; Q448-Y455 HydrophobicContact CG-CD2 3.94Å; Q448-Y455 HydrophobicContact CG-CE1 4.37Å; Q448-Y455 HydrophobicContact CG-CE2 4.48Å; Q448-Y455 HydrophobicContact CG-CG 3.56Å; Q451-Y455 PolarHBondContact O-N 3.49Å; I453-Y455 VanDerWaalsContact C-N 3.29Å; I453-Y455 PolarHBondContact O-N 3.48Å; Y455-S458 PolarHBondContact O-OG 3.03Å; Y455-I459 HydrophobicContact CD1-CD1 4.32Å; Y455-I459 HydrophobicContact CD2-CD1 3.96Å; Y455-I459 HydrophobicContact CE1-CD1 3.74Å; Y455-I459 HydrophobicContact CE2-CD1 3.32Å; Y455-I459 HydrophobicContact CE2-CG1 4.44Å; Y455-I459 HydrophobicContact CG-CD1 4.41Å; Y455-I459 PolarHBondContact O-N 2.89Å; Y455-I459 VanDerWaalsContact OH-CD1 3.29Å; Y455-I459 WeakPolarHBondContact OH-CD1 3.41Å; Y455-F504 HydrophobicContact CE2-CE1 4.03Å; Y455-F504 HydrophobicContact CE2-CZ 4.12Å
456	T	89.1	Confident	85.1	Confident	13 Å²	13	17.5 Å²	17.5	8%	0.08	10%	0.097	C	C	.	.	H	α-helix	trans	-64.2	-45	-179.3	-56.4	0	0	0	0	110.9	L156 S160 L452 I453 S460	L156-T456 HydrophobicContact CD1-CG2 3.45Å; L156-T456 VanDerWaalsContact CD1-CG2 3.45Å; L156-T456 WeakPolarHBondContact CD1-O 3.39Å; L156-T456 HydrophobicContact CG-CG2 4.14Å; S160-T456 PolarHBondContact OG-OG1 3.06Å; S160-T456 VanDerWaalsContact OG-OG1 3.12Å; L452-T456 PolarHBondContact O-N 2.9Å; L452-T456 VanDerWaalsContact O-N 3.08Å; L452-T456 PolarHBondContact O-OG1 3.38Å; I453-T456 PolarHBondContact O-N 3.1Å; I453-T456 VanDerWaalsContact O-N 3.13Å; T456-S460 WeakPolarHBondContact O-CB 3.45Å; T456-S460 PolarHBondContact O-N 3.48Å; T456-S460 PolarHBondContact O-OG 3.2Å
457	E	91.9	Very high	86.4	Confident	38 Å²	38	12 Å²	12	18%	0.178	6%	0.064	C	C	.	.	H	α-helix	trans	-74	-32.3	-176.4	-70.8	-64	142	0	0	113.3	F101 I453 S461 Y526	F101-E457 HydrophobicContact CD1-CB 4.4Å; F101-E457 HydrophobicContact CD1-CG 3.51Å; F101-E457 HydrophobicContact CE1-CB 4Å; F101-E457 HydrophobicContact CE1-CG 3.58Å; F101-E457 HydrophobicContact CG-CG 4.15Å; F101-E457 HydrophobicContact CZ-CB 4.5Å; F101-E457 HydrophobicContact CZ-CG 4.2Å; I453-E457 HydrophobicContact CG2-CG 4.02Å; I453-E457 WeakPolarHBondContact O-CB 3.2Å; I453-E457 WeakPolarHBondContact O-CG 3.26Å; I453-E457 PolarHBondContact O-N 3.12Å; E457-S461 VanDerWaalsContact O-CB 3.3Å; E457-S461 WeakPolarHBondContact O-CB 3.39Å; E457-S461 PolarHBondContact O-N 3.18Å; E457-S461 PolarHBondContact O-OG 3.49Å; E457-Y526 HydrophobicContact CB-CE2 3.87Å
458	S	91.4	Very high	88	Confident	7 Å²	7	11.1 Å²	11.1	5%	0.049	6%	0.058	C	C	.	.	H	α-helix	trans	-64.5	-49.5	173.9	59.5	0	0	0	0	111.5	H454 Y455 S460 S461 Y462	H454-S458 WeakPolarHBondContact O-CB 3.28Å; H454-S458 PolarHBondContact O-N 3.28Å; H454-S458 PolarHBondContact O-OG 3.2Å; Y455-S458 PolarHBondContact O-OG 3.03Å; S458-S460 VanDerWaalsContact C-N 3.33Å; S458-S460 PolarHBondContact O-N 3.01Å; S458-S461 CarbonylContact O-C 3.54Å; S458-S461 WeakPolarHBondContact O-CA 3.41Å; S458-S461 VanDerWaalsContact O-CB 3.32Å; S458-S461 WeakPolarHBondContact O-CB 3.33Å; S458-S461 PolarHBondContact O-N 3.29Å; S458-Y462 WeakPolarHBondContact O-CD1 3.18Å; S458-Y462 WeakPolarHBondContact O-CD2 3.39Å; S458-Y462 WeakPolarHBondContact O-CE2 3.22Å; S458-Y462 PolarHBondContact O-N 2.9Å
459	I	91.2	Very high	89.6	Confident	3 Å²	3	10.8 Å²	10.8	2%	0.015	6%	0.056	C	C	.	.	H	α-helix	trans	-61.5	-42.8	176.3	-67.6	168.9	0	0	0	111.2	V155 L156 Y455 S461 Y462 L463 F504	V155-I459 HydrophobicContact CG1-CD1 4.21Å; L156-I459 HydrophobicContact CB-CG2 4.34Å; L156-I459 HydrophobicContact CD1-CB 4.01Å; L156-I459 HydrophobicContact CD1-CG2 4.05Å; Y455-I459 HydrophobicContact CD1-CD1 4.32Å; Y455-I459 HydrophobicContact CD2-CD1 3.96Å; Y455-I459 HydrophobicContact CE1-CD1 3.74Å; Y455-I459 HydrophobicContact CE2-CD1 3.32Å; Y455-I459 HydrophobicContact CE2-CG1 4.44Å; Y455-I459 HydrophobicContact CG-CD1 4.41Å; Y455-I459 PolarHBondContact O-N 2.89Å; Y455-I459 VanDerWaalsContact OH-CD1 3.29Å; Y455-I459 WeakPolarHBondContact OH-CD1 3.41Å; I459-S461 PolarHBondContact O-N 2.82Å; I459-Y462 PolarHBondContact O-N 3.32Å; I459-L463 HydrophobicContact CG2-CD1 4.07Å; I459-L463 PolarHBondContact O-N 3.1Å; I459-L463 VanDerWaalsContact O-N 3.09Å; I459-F504 HydrophobicContact CD1-CZ 4.11Å
460	S	93.6	Very high	91.2	Very high	7 Å²	7	8.8 Å²	8.8	5%	0.049	5%	0.045	C	C	.	.	H	α-helix	trans	-57.4	-39.7	174.3	-61	0	0	0	0	111.5	L156 T456 S458 Y462 G464 P465	L156-S460 VanDerWaalsContact CD2-OG 3.26Å; L156-S460 WeakPolarHBondContact CD2-OG 3.35Å; T456-S460 WeakPolarHBondContact O-CB 3.45Å; T456-S460 PolarHBondContact O-N 3.48Å; T456-S460 PolarHBondContact O-OG 3.2Å; S458-S460 VanDerWaalsContact C-N 3.33Å; S458-S460 PolarHBondContact O-N 3.01Å; S460-Y462 VanDerWaalsContact C-N 3.32Å; S460-Y462 PolarHBondContact O-N 3.02Å; S460-G464 WeakPolarHBondContact O-CA 3.46Å; S460-G464 PolarHBondContact O-N 3.49Å; S460-P465 WeakPolarHBondContact O-CD 3.28Å
461	S	95.5	Very high	92.6	Very high	0 Å²	0	8.7 Å²	8.7	0%	0	4%	0.043	C	C	.	.	H	α-helix	trans	-71.7	-20.9	176.4	-61.9	0	0	0	0	114	T286 E457 S458 I459 P465 Y526	T286-S461 WeakPolarHBondContact CG2-OG 3.37Å; E457-S461 VanDerWaalsContact O-CB 3.3Å; E457-S461 WeakPolarHBondContact O-CB 3.39Å; E457-S461 PolarHBondContact O-N 3.18Å; E457-S461 PolarHBondContact O-OG 3.49Å; S458-S461 CarbonylContact O-C 3.54Å; S458-S461 WeakPolarHBondContact O-CA 3.41Å; S458-S461 VanDerWaalsContact O-CB 3.32Å; S458-S461 WeakPolarHBondContact O-CB 3.33Å; S458-S461 PolarHBondContact O-N 3.29Å; I459-S461 PolarHBondContact O-N 2.82Å; S461-P465 WeakPolarHBondContact O-CD 3.39Å; S461-P465 VanDerWaalsContact O-CG 3.25Å; S461-P465 WeakPolarHBondContact O-CG 3.41Å; S461-Y526 WeakPolarHBondContact CB-O 3.44Å; S461-Y526 WeakPolarHBondContact OG-CD2 3.38Å
462	Y	94.4	Very high	93.4	Very high	2 Å²	2	7.6 Å²	7.6	1%	0.008	4%	0.04	C	C	.	.	H	α-helix	trans	-88.4	-30.6	178.1	-55.4	-29.2	0	0	0	113.1	S458 I459 S460 G496 R499 M500 E503 F529 L533	S458-Y462 WeakPolarHBondContact O-CD1 3.18Å; S458-Y462 WeakPolarHBondContact O-CD2 3.39Å; S458-Y462 WeakPolarHBondContact O-CE2 3.22Å; S458-Y462 PolarHBondContact O-N 2.9Å; I459-Y462 PolarHBondContact O-N 3.32Å; S460-Y462 VanDerWaalsContact C-N 3.32Å; S460-Y462 PolarHBondContact O-N 3.02Å; Y462-G496 WeakPolarHBondContact O-CA 3.26Å; Y462-R499 HydrophobicContact CD1-CB 4.37Å; Y462-R499 HydrophobicContact CD1-CG 3.66Å; Y462-R499 HydrophobicContact CE1-CG 3.49Å; Y462-R499 VanDerWaalsContact CE1-CG 3.49Å; Y462-R499 HydrophobicContact CG-CG 4.3Å; Y462-R499 PolarHBondContact OH-NH2 3.49Å; Y462-M500 HydrophobicContact CD2-CB 3.8Å; Y462-M500 HydrophobicContact CD2-CG 4.07Å; Y462-M500 HydrophobicContact CG-CB 4.34Å; Y462-E503 VanDerWaalsContact OH-CD 3.3Å; Y462-E503 PolarHBondContact OH-OE1 3.49Å; Y462-E503 PolarHBondContact OH-OE2 3.11Å; Y462-F529 AromaticContact CD1-CD1 3.57Å; Y462-F529 HydrophobicContact CD1-CD1 3.57Å; Y462-F529 AromaticContact CD1-CE1 3.76Å; Y462-F529 HydrophobicContact CD1-CE1 3.76Å; Y462-F529 AromaticContact CE1-CD1 3.99Å; Y462-F529 HydrophobicContact CE1-CD1 3.99Å; Y462-F529 HydrophobicContact CE1-CE1 4.48Å; Y462-L533 WeakPolarHBondContact O-CD2 3.38Å
463	L	94.8	Very high	94.1	Very high	4 Å²	4	8 Å²	8	2%	0.021	4%	0.042	C	C	.	.	H	α-helix	trans	-114.3	-29	-171.9	-59.1	177.2	0	0	0	113.9	F151 I152 I459 L493 L497 M500	F151-L463 HydrophobicContact CD1-CD1 4.27Å; F151-L463 HydrophobicContact CE1-CD1 3.92Å; I152-L463 HydrophobicContact CD1-CB 3.92Å; I152-L463 HydrophobicContact CG1-CB 4.12Å; I152-L463 HydrophobicContact CG1-CD1 3.8Å; I459-L463 HydrophobicContact CG2-CD1 4.07Å; I459-L463 PolarHBondContact O-N 3.1Å; I459-L463 VanDerWaalsContact O-N 3.09Å; L463-L493 HydrophobicContact CD2-CD1 3.98Å; L463-L497 HydrophobicContact CD2-CD2 4.1Å; L463-M500 HydrophobicContact CD1-SD 4.18Å
464	G	95.4	Very high	94.4	Very high	0 Å²	0	7.8 Å²	7.8	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-72.4	-42.3	-177.8	0	0	0	0	0	115.8	S460 I467 A468	S460-G464 WeakPolarHBondContact O-CA 3.46Å; S460-G464 PolarHBondContact O-N 3.49Å; G464-I467 WeakPolarHBondContact O-CB 3.32Å; G464-I467 PolarHBondContact O-N 3.22Å; G464-A468 PolarHBondContact O-N 3.02Å
465	P	97.3	Very high	94.8	Very high	0 Å²	0	6.5 Å²	6.5	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-57.9	-40.8	-172	-28.2	35.8	0	0	0	116.2	I285 S460 S461 I467 A468 A469 S530 L533 F534	I285-P465 HydrophobicContact CG2-CB 3.79Å; I285-P465 HydrophobicContact CG2-CG 4.04Å; S460-P465 WeakPolarHBondContact O-CD 3.28Å; S461-P465 WeakPolarHBondContact O-CD 3.39Å; S461-P465 VanDerWaalsContact O-CG 3.25Å; S461-P465 WeakPolarHBondContact O-CG 3.41Å; P465-I467 VanDerWaalsContact C-N 3.28Å; P465-I467 PolarHBondContact O-N 3.41Å; P465-A468 PolarHBondContact O-N 2.95Å; P465-A469 WeakPolarHBondContact O-CB 3.27Å; P465-A469 PolarHBondContact O-N 2.79Å; P465-S530 WeakPolarHBondContact CG-OG 3.26Å; P465-L533 HydrophobicContact CB-CB 4.17Å; P465-L533 HydrophobicContact CB-CD2 4.13Å; P465-L533 HydrophobicContact CB-CG 4.13Å; P465-L533 HydrophobicContact CG-CD2 4.17Å; P465-F534 HydrophobicContact CB-CB 4.01Å; P465-F534 WeakPolarHBondContact O-CD2 3.41Å
466	P	97.2	Very high	95.3	Very high	3 Å²	3	10.1 Å²	10.1	2%	0.019	5%	0.051	C	C	.	.	H	α-helix	trans	-61.5	-37.1	175.6	-23.7	35.2	0	0	0	112.7	A469 V470 L489 L533	P466-A469 PolarHBondContact O-N 2.87Å; P466-V470 PolarHBondContact O-N 3.49Å; P466-V470 VanDerWaalsContact O-N 3.14Å; P466-L489 HydrophobicContact CB-CD2 4.04Å; P466-L489 WeakPolarHBondContact O-CD2 3.34Å; P466-L533 HydrophobicContact CG-CD1 4.13Å; P466-L533 HydrophobicContact CG-CD2 3.81Å; P466-L533 HydrophobicContact CG-CG 3.79Å
467	I	96.4	Very high	95.6	Very high	5 Å²	5	11 Å²	11	3%	0.026	6%	0.057	C	C	.	.	H	α-helix	trans	-67	-50.8	176.8	-57.6	171.7	0	0	0	109.1	L145 L148 I152 G464 P465 A469 V470 Y471 L489	L145-I467 HydrophobicContact CD2-CG1 4.23Å; L145-I467 HydrophobicContact CD2-CG2 4.47Å; L148-I467 HydrophobicContact CD2-CD1 3.85Å; L148-I467 HydrophobicContact CD2-CG1 4.2Å; L148-I467 HydrophobicContact CG-CD1 4.35Å; I152-I467 HydrophobicContact CD1-CD1 4.02Å; G464-I467 WeakPolarHBondContact O-CB 3.32Å; G464-I467 PolarHBondContact O-N 3.22Å; P465-I467 VanDerWaalsContact C-N 3.28Å; P465-I467 PolarHBondContact O-N 3.41Å; I467-A469 VanDerWaalsContact C-N 3.27Å; I467-A469 PolarHBondContact O-N 3.45Å; I467-V470 PolarHBondContact O-N 2.93Å; I467-V470 VanDerWaalsContact O-N 3.16Å; I467-Y471 HydrophobicContact CG2-CD2 3.73Å; I467-Y471 HydrophobicContact CG2-CE2 3.74Å; I467-Y471 WeakPolarHBondContact O-CD2 3.49Å; I467-Y471 PolarHBondContact O-N 3.49Å; I467-L489 HydrophobicContact CG1-CD2 4.23Å
468	A	97.3	Very high	95.7	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-52.6	-45.4	175	0	0	0	0	0	112	I285 L288 W289 G464 P465 V470 Y471 V472 F534	I285-A468 HydrophobicContact CG2-CB 4.36Å; L288-A468 HydrophobicContact CD2-CB 4.23Å; W289-A468 HydrophobicContact CB-CB 4.03Å; G464-A468 PolarHBondContact O-N 3.02Å; P465-A468 PolarHBondContact O-N 2.95Å; A468-V470 PolarHBondContact O-N 3.46Å; A468-Y471 PolarHBondContact O-N 2.85Å; A468-V472 WeakPolarHBondContact O-CB 3.34Å; A468-V472 VanDerWaalsContact O-CG2 3.28Å; A468-V472 WeakPolarHBondContact O-CG2 3.32Å; A468-V472 PolarHBondContact O-N 3.43Å; A468-F534 HydrophobicContact CB-CD2 4.14Å; A468-F534 HydrophobicContact CB-CE2 3.96Å
469	A	98	Very high	95.8	Very high	0 Å²	0	16.5 Å²	16.5	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-58	-47.9	178.8	0	0	0	0	0	111.9	P465 P466 I467 L473 F534 M538	P465-A469 WeakPolarHBondContact O-CB 3.27Å; P465-A469 PolarHBondContact O-N 2.79Å; P466-A469 PolarHBondContact O-N 2.87Å; I467-A469 VanDerWaalsContact C-N 3.27Å; I467-A469 PolarHBondContact O-N 3.45Å; A469-L473 WeakPolarHBondContact O-CB 3.13Å; A469-L473 VanDerWaalsContact O-CG 3.29Å; A469-L473 WeakPolarHBondContact O-CG 3.07Å; A469-L473 PolarHBondContact O-N 3.26Å; A469-F534 VanDerWaalsContact CA-CE2 3.45Å; A469-F534 HydrophobicContact CB-CD2 3.8Å; A469-F534 HydrophobicContact CB-CE2 3.89Å; A469-F534 HydrophobicContact CB-CG 4.49Å; A469-M538 HydrophobicContact CB-CG 3.62Å
470	V	97.1	Very high	96.1	Very high	1 Å²	1	16.4 Å²	16.4	1%	0.006	8%	0.077	C	C	.	.	H	α-helix	trans	-65.2	-41.7	178.4	168.9	0	0	0	0	112.1	L132 F136 P466 I467 A468 L473 A474 A485 L489 V541	L132-V470 HydrophobicContact CD1-CG1 3.97Å; L132-V470 HydrophobicContact CD2-CG1 4.44Å; F136-V470 HydrophobicContact CE2-CG1 3.97Å; P466-V470 PolarHBondContact O-N 3.49Å; P466-V470 VanDerWaalsContact O-N 3.14Å; I467-V470 PolarHBondContact O-N 2.93Å; I467-V470 VanDerWaalsContact O-N 3.16Å; A468-V470 PolarHBondContact O-N 3.46Å; V470-L473 PolarHBondContact O-N 3.33Å; V470-A474 WeakPolarHBondContact O-CB 3.18Å; V470-A474 PolarHBondContact O-N 2.89Å; V470-A485 HydrophobicContact CG1-CB 4.08Å; V470-A485 HydrophobicContact CG2-CB 4.44Å; V470-L489 HydrophobicContact CB-CD1 4.43Å; V470-L489 HydrophobicContact CB-CD2 4.38Å; V470-L489 HydrophobicContact CB-CG 4.42Å; V470-L489 HydrophobicContact CG1-CD1 4.39Å; V470-L489 HydrophobicContact CG2-CD1 3.95Å; V470-L489 HydrophobicContact CG2-CD2 3.89Å; V470-L489 HydrophobicContact CG2-CG 3.61Å; V470-V541 HydrophobicContact CG2-CG2 3.93Å
471	Y	96.9	Very high	96.1	Very high	6 Å²	6	16.5 Å²	16.5	2%	0.024	8%	0.077	C	C	.	.	H	α-helix	trans	-68.1	-40	179.4	-86.8	-90.8	0	0	0	113	Y120 M128 Y131 L132 T293 I467 A468 L473 A474 I475	Y120-Y471 HydrophobicContact CE1-CD1 4.46Å; Y120-Y471 HydrophobicContact CE1-CE1 4.44Å; Y120-Y471 WeakPolarHBondContact OH-CD1 3.46Å; M128-Y471 HydrophobicContact CB-CE1 4.32Å; M128-Y471 VanDerWaalsContact CB-OH 3.31Å; M128-Y471 WeakPolarHBondContact CB-OH 3.22Å; M128-Y471 PolarHBondContact O-OH 2.92Å; Y131-Y471 HydrophobicContact CD1-CD1 4.09Å; Y131-Y471 AromaticContact CD1-CE1 3.69Å; Y131-Y471 HydrophobicContact CD1-CE1 3.69Å; Y131-Y471 HydrophobicContact CE1-CD1 4.14Å; Y131-Y471 HydrophobicContact CE1-CE1 4.22Å; L132-Y471 HydrophobicContact CD1-CD2 4.02Å; L132-Y471 HydrophobicContact CD1-CE1 4.11Å; L132-Y471 HydrophobicContact CD1-CE2 3.4Å; L132-Y471 VanDerWaalsContact CD1-CZ 3.43Å; L132-Y471 WeakPolarHBondContact CD1-OH 3.39Å; L132-Y471 HydrophobicContact CD2-CD1 4.47Å; L132-Y471 HydrophobicContact CD2-CE1 4.27Å; L132-Y471 HydrophobicContact CG-CE1 3.98Å; L132-Y471 HydrophobicContact CG-CE2 4.18Å; T293-Y471 HydrophobicContact CG2-CD1 4.06Å; T293-Y471 HydrophobicContact CG2-CD2 3.74Å; T293-Y471 HydrophobicContact CG2-CE2 4.48Å; T293-Y471 HydrophobicContact CG2-CG 3.49Å; T293-Y471 VanDerWaalsContact CG2-CG 3.49Å; I467-Y471 HydrophobicContact CG2-CD2 3.73Å; I467-Y471 HydrophobicContact CG2-CE2 3.74Å; I467-Y471 WeakPolarHBondContact O-CD2 3.49Å; I467-Y471 PolarHBondContact O-N 3.49Å; A468-Y471 PolarHBondContact O-N 2.85Å; Y471-L473 VanDerWaalsContact C-N 3.33Å; Y471-L473 PolarHBondContact O-N 2.9Å; Y471-A474 PolarHBondContact O-N 3.5Å; Y471-I475 PolarHBondContact O-N 3.34Å
472	V	97.6	Very high	96	Very high	28 Å²	28	18.2 Å²	18.2	17%	0.17	9%	0.085	C	C	.	.	H	α-helix	trans	-58.4	-49.1	172.3	169.9	0	0	0	0	110	L288 A468 I475 F476 F534	L288-V472 HydrophobicContact CD2-CG2 3.25Å; L288-V472 HydrophobicContact CG-CG2 4.5Å; A468-V472 WeakPolarHBondContact O-CB 3.34Å; A468-V472 VanDerWaalsContact O-CG2 3.28Å; A468-V472 WeakPolarHBondContact O-CG2 3.32Å; A468-V472 PolarHBondContact O-N 3.43Å; V472-I475 PolarHBondContact O-N 3.34Å; V472-F476 HydrophobicContact CG1-CD2 4.06Å; V472-F476 WeakPolarHBondContact O-CB 3.38Å; V472-F476 VanDerWaalsContact O-CD2 3.31Å; V472-F476 WeakPolarHBondContact O-CD2 3.45Å; V472-F476 PolarHBondContact O-N 3.5Å; V472-F534 HydrophobicContact CG2-CZ 4.4Å
473	L	97.6	Very high	95.9	Very high	9 Å²	9	22.9 Å²	22.9	5%	0.047	11%	0.107	C	C	.	.	H	α-helix	trans	-67.2	-37	179.9	-74.6	178.4	0	0	0	112.8	A469 V470 Y471 I475 C477 V480 M538 V541 L542	A469-L473 WeakPolarHBondContact O-CB 3.13Å; A469-L473 VanDerWaalsContact O-CG 3.29Å; A469-L473 WeakPolarHBondContact O-CG 3.07Å; A469-L473 PolarHBondContact O-N 3.26Å; V470-L473 PolarHBondContact O-N 3.33Å; Y471-L473 VanDerWaalsContact C-N 3.33Å; Y471-L473 PolarHBondContact O-N 2.9Å; L473-I475 VanDerWaalsContact C-N 3.3Å; L473-I475 PolarHBondContact O-N 2.87Å; L473-C477 HydrophobicContact CD2-CB 4.01Å; L473-C477 CarbonylContact O-C 3.58Å; L473-C477 WeakPolarHBondContact O-CA 3.27Å; L473-C477 VanDerWaalsContact O-CB 3.25Å; L473-C477 WeakPolarHBondContact O-CB 3.15Å; L473-C477 PolarHBondContact O-N 3.08Å; L473-C477 VanDerWaalsContact O-O 3.09Å; L473-V480 HydrophobicContact CB-CG2 4.12Å; L473-M538 HydrophobicContact CD1-CB 4.19Å; L473-M538 HydrophobicContact CD1-CE 4.37Å; L473-M538 HydrophobicContact CD1-CG 4.03Å; L473-M538 HydrophobicContact CD2-CE 3.65Å; L473-M538 HydrophobicContact CG-CE 3.98Å; L473-M538 HydrophobicContact CG-CG 4.41Å; L473-V541 HydrophobicContact CD1-CB 3.68Å; L473-V541 HydrophobicContact CD1-CG1 3.51Å; L473-V541 HydrophobicContact CD1-CG2 4.3Å; L473-L542 HydrophobicContact CD1-CD2 4.47Å; L473-L542 HydrophobicContact CD1-CG 4.17Å; L473-L542 HydrophobicContact CD2-CD1 4.32Å; L473-L542 HydrophobicContact CD2-CD2 3.89Å; L473-L542 HydrophobicContact CD2-CG 4.16Å
474	A	95.7	Very high	96	Very high	0 Å²	0	22.7 Å²	22.7	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-58.9	-43.4	175.5	0	0	0	0	0	111.6	Y131 L132 R135 F136 V470 Y471	Y131-A474 HydrophobicContact CE1-CB 4.08Å; L132-A474 HydrophobicContact CD2-CB 3.69Å; R135-A474 HydrophobicContact CG-CB 4.09Å; R135-A474 PolarHBondContact NE-O 3.32Å; F136-A474 HydrophobicContact CE2-CB 3.88Å; F136-A474 HydrophobicContact CZ-CB 3.65Å; V470-A474 WeakPolarHBondContact O-CB 3.18Å; V470-A474 PolarHBondContact O-N 2.89Å; Y471-A474 PolarHBondContact O-N 3.5Å
475	I	95.9	Very high	96	Very high	0 Å²	0	22.7 Å²	22.7	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-76.4	-49.1	-179.4	-74.3	172.5	0	0	0	111.6	I115 F116 I119 Y131 Y471 V472 L473 C560 W561	I115-I475 HydrophobicContact CG2-CG2 4.44Å; F116-I475 HydrophobicContact CB-CD1 4.48Å; F116-I475 HydrophobicContact CD1-CD1 3.19Å; F116-I475 HydrophobicContact CE1-CD1 3.38Å; F116-I475 HydrophobicContact CG-CD1 3.87Å; F116-I475 HydrophobicContact CZ-CD1 4.16Å; I119-I475 HydrophobicContact CD1-CB 4.2Å; I119-I475 HydrophobicContact CD1-CD1 4.43Å; I119-I475 HydrophobicContact CD1-CG1 4.01Å; I119-I475 HydrophobicContact CD1-CG2 3.41Å; I119-I475 VanDerWaalsContact CD1-CG2 3.41Å; Y131-I475 HydrophobicContact CE1-CG1 4.48Å; Y131-I475 WeakPolarHBondContact OH-CG1 3.33Å; Y471-I475 PolarHBondContact O-N 3.34Å; V472-I475 PolarHBondContact O-N 3.34Å; L473-I475 VanDerWaalsContact C-N 3.3Å; L473-I475 PolarHBondContact O-N 2.87Å; I475-C560 CarbonylContact O-C 3.56Å; I475-C560 WeakPolarHBondContact O-CA 3.34Å; I475-C560 WeakPolarHBondContact O-CB 3.24Å; I475-W561 HydrophobicContact CG2-CB 4.23Å; I475-W561 WeakPolarHBondContact O-CB 3.48Å; I475-W561 PolarHBondContact O-N 3.13Å
476	F	96.8	Very high	95.9	Very high	87 Å²	87	24.6 Å²	24.6	38%	0.382	11%	0.114	S	C	.	.	H	α-helix	trans	-96	-21.5	-168.3	-68.4	-72	0	0	0	114.5	I115 V472 W561	I115-F476 HydrophobicContact CD1-CZ 4.26Å; I115-F476 HydrophobicContact CG2-CE1 4.19Å; I115-F476 HydrophobicContact CG2-CE2 4.03Å; I115-F476 HydrophobicContact CG2-CZ 3.39Å; V472-F476 HydrophobicContact CG1-CD2 4.06Å; V472-F476 WeakPolarHBondContact O-CB 3.38Å; V472-F476 VanDerWaalsContact O-CD2 3.31Å; V472-F476 WeakPolarHBondContact O-CD2 3.45Å; V472-F476 PolarHBondContact O-N 3.5Å; F476-W561 HydrophobicContact CD1-CB 3.95Å; F476-W561 HydrophobicContact CD1-CG 4.05Å; F476-W561 HydrophobicContact CE1-CB 4.25Å; F476-W561 HydrophobicContact CE1-CD2 4.11Å; F476-W561 AromaticContact CE1-CG 3.99Å; F476-W561 HydrophobicContact CE1-CG 3.99Å
477	C	95.9	Very high	95.8	Very high	30 Å²	30	31 Å²	31	20%	0.203	14%	0.139	C	C	.	.			trans	-114.9	105.5	-175.2	-165.8	0	0	0	0	111.7	R135 L473 R479 V480	R135-C477 PolarHBondContact NH2-O 3.49Å; L473-C477 HydrophobicContact CD2-CB 4.01Å; L473-C477 CarbonylContact O-C 3.58Å; L473-C477 WeakPolarHBondContact O-CA 3.27Å; L473-C477 VanDerWaalsContact O-CB 3.25Å; L473-C477 WeakPolarHBondContact O-CB 3.15Å; L473-C477 PolarHBondContact O-N 3.08Å; L473-C477 VanDerWaalsContact O-O 3.09Å; C477-R479 PolarHBondContact O-N 2.8Å; C477-V480 HydrophobicContact CB-CG2 3.92Å; C477-V480 PolarHBondContact O-N 3.41Å
478	K	93.9	Very high	95.8	Very high	94 Å²	94	30.8 Å²	30.8	41%	0.409	14%	0.137	S	C	.	.	T	Hydrogen-bonded Turn	trans	-65.1	-24.8	176.2	73.7	173.5	-166.6	162.1	0	113.6	R135 V480 D553 L556	R135-K478 PolarHBondContact NH2-O 3.45Å; K478-V480 VanDerWaalsContact C-N 3.28Å; K478-V480 PolarHBondContact O-N 2.99Å; K478-D553 IonicContact NZ-OD1 3.46Å; K478-D553 IonicContact NZ-OD2 3Å; K478-D553 PolarHBondContact NZ-OD2 2.87Å; K478-L556 HydrophobicContact CB-CD1 4.34Å
479	R	94	Very high	95.7	Very high	67 Å²	67	30.9 Å²	30.9	25%	0.253	14%	0.138	S	C	.	.	T	Hydrogen-bonded Turn	trans	-70.8	-21.2	-175.4	-176.2	58.8	-172.8	91.3	-4.8	113.8	C477 S545 L546 T548	C477-R479 PolarHBondContact O-N 2.8Å; R479-S545 PolarHBondContact NH1-O 3.19Å; R479-S545 PolarHBondContact NH2-O 3.01Å; R479-L546 HydrophobicContact CG-CD2 3.71Å; R479-L546 VanDerWaalsContact NH2-C 3.32Å; R479-L546 PolarHBondContact NH2-O 3.36Å; R479-T548 PolarHBondContact NH1-O 3.07Å; R479-T548 PolarHBondContact NH2-O 2.96Å
480	V	96	Very high	95.6	Very high	1 Å²	1	34.2 Å²	34.2	1%	0.006	15%	0.154	C	C	.	.			trans	-71.6	138.4	-177.9	178.7	0	0	0	0	111.1	R135 F136 L473 C477 K478 V541 L542 S545	R135-V480 PolarHBondContact NH1-O 3.38Å; R135-V480 PolarHBondContact NH2-O 3.01Å; F136-V480 HydrophobicContact CE1-CB 3.98Å; F136-V480 HydrophobicContact CE1-CG1 3.56Å; F136-V480 WeakPolarHBondContact CE1-O 3.41Å; F136-V480 HydrophobicContact CZ-CB 4.3Å; F136-V480 HydrophobicContact CZ-CG1 3.61Å; L473-V480 HydrophobicContact CB-CG2 4.12Å; C477-V480 HydrophobicContact CB-CG2 3.92Å; C477-V480 PolarHBondContact O-N 3.41Å; K478-V480 VanDerWaalsContact C-N 3.28Å; K478-V480 PolarHBondContact O-N 2.99Å; V480-V541 HydrophobicContact CB-CG1 4.48Å; V480-V541 HydrophobicContact CG1-CG1 3.5Å; V480-V541 HydrophobicContact CG2-CG1 4.09Å; V480-L542 HydrophobicContact CG2-CD2 3.99Å; V480-S545 WeakPolarHBondContact CA-OG 3.26Å
481	N	93.9	Very high	95.6	Very high	9 Å²	9	36.9 Å²	36.9	5%	0.048	17%	0.17	C	C	.	.			trans	-127.4	177.1	-179.9	61.4	28.5	0	0	0	111.7	Q483 G484 A485 S545 T548 K549 I551	N481-Q483 PolarHBondContact O-N 2.93Å; N481-G484 PolarHBondContact O-N 3.27Å; N481-G484 PolarHBondContact OD1-N 3.47Å; N481-G484 VanDerWaalsContact OD1-N 3.16Å; N481-A485 PolarHBondContact O-N 2.74Å; N481-S545 PolarHBondContact N-OG 3.38Å; N481-T548 PolarHBondContact ND2-OG1 3.17Å; N481-T548 PolarHBondContact OD1-OG1 3.33Å; N481-K549 PolarHBondContact ND2-O 2.93Å; N481-I551 HydrophobicContact CB-CD1 4.01Å; N481-I551 HydrophobicContact CB-CG1 4.03Å
482	E	93.4	Very high	95.5	Very high	36 Å²	36	36.6 Å²	36.6	17%	0.168	17%	0.169	C	C	.	.	H	α-helix	trans	-57.8	-46.5	-175.3	-170	-84.4	168.5	0	0	113.1	F136 G484 A485 F486	F136-E482 HydrophobicContact CB-CB 4.01Å; F136-E482 HydrophobicContact CB-CG 4.47Å; E482-G484 VanDerWaalsContact C-N 3.35Å; E482-G484 PolarHBondContact O-N 3.15Å; E482-A485 PolarHBondContact O-N 2.94Å; E482-F486 WeakPolarHBondContact O-CB 2.99Å; E482-F486 PolarHBondContact O-N 2.99Å
483	Q	93.6	Very high	95.4	Very high	101 Å²	101	36.6 Å²	36.6	47%	0.472	17%	0.168	S	C	.	.	H	α-helix	trans	-63.2	-42.5	-176.6	-68.1	-176.1	-17.5	0	0	111.8	N481 W487 I544	N481-Q483 PolarHBondContact O-N 2.93Å; Q483-W487 VanDerWaalsContact O-CD1 3.27Å; Q483-W487 PolarHBondContact O-N 3.48Å; Q483-W487 VanDerWaalsContact O-N 3.09Å; Q483-I544 HydrophobicContact CB-CG2 4.24Å
484	G	95.5	Very high	95.3	Very high	0 Å²	0	38.5 Å²	38.5	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-64.3	-46.7	175.4	0	0	0	0	0	112.1	N481 E482 G488 V541	N481-G484 PolarHBondContact O-N 3.27Å; N481-G484 PolarHBondContact OD1-N 3.47Å; N481-G484 VanDerWaalsContact OD1-N 3.16Å; E482-G484 VanDerWaalsContact C-N 3.35Å; E482-G484 PolarHBondContact O-N 3.15Å; G484-G488 PolarHBondContact O-N 3.38Å; G484-V541 WeakPolarHBondContact O-CA 3.47Å; G484-V541 WeakPolarHBondContact O-CG2 3.4Å
485	A	95.8	Very high	95.3	Very high	0 Å²	0	41.7 Å²	41.7	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-60.8	-46.5	178.4	0	0	0	0	0	112.1	F136 L141 V470 N481 E482 L489	F136-A485 HydrophobicContact CD2-CB 3.91Å; F136-A485 HydrophobicContact CE2-CB 3.72Å; F136-A485 HydrophobicContact CG-CB 4.48Å; F136-A485 HydrophobicContact CZ-CB 4.21Å; L141-A485 HydrophobicContact CD2-CB 4.19Å; V470-A485 HydrophobicContact CG1-CB 4.08Å; V470-A485 HydrophobicContact CG2-CB 4.44Å; N481-A485 PolarHBondContact O-N 2.74Å; E482-A485 PolarHBondContact O-N 2.94Å; A485-L489 WeakPolarHBondContact O-CD1 3.46Å; A485-L489 WeakPolarHBondContact O-CG 3.33Å; A485-L489 PolarHBondContact O-N 2.83Å
486	F	95.3	Very high	95.3	Very high	39 Å²	39	41.7 Å²	41.7	17%	0.171	20%	0.201	C	C	.	.	H	α-helix	trans	-63	-54.2	-179.1	178.8	-98.8	0	0	0	112.2	R140 E482 G488 L489 M490	R140-F486 HydrophobicContact CB-CD2 4.33Å; R140-F486 HydrophobicContact CB-CE2 4.24Å; E482-F486 WeakPolarHBondContact O-CB 2.99Å; E482-F486 PolarHBondContact O-N 2.99Å; F486-G488 VanDerWaalsContact C-N 3.34Å; F486-G488 PolarHBondContact O-N 2.91Å; F486-L489 PolarHBondContact O-N 3.43Å; F486-M490 HydrophobicContact CD1-CG 4.26Å; F486-M490 HydrophobicContact CE1-CG 3.83Å; F486-M490 HydrophobicContact CE2-CG 4.22Å; F486-M490 HydrophobicContact CE2-SD 4.42Å; F486-M490 HydrophobicContact CZ-CG 3.81Å; F486-M490 HydrophobicContact CZ-SD 4.19Å; F486-M490 WeakPolarHBondContact O-CG 3.03Å; F486-M490 PolarHBondContact O-N 3.05Å
487	W	95.3	Very high	95.1	Very high	139 Å²	139	40 Å²	40	53%	0.527	20%	0.195	S	C	.	.	H	α-helix	trans	-68.6	-33.4	-178.4	-76.7	113.9	0	0	0	112.8	Q483 L489 M490 V491 I544	Q483-W487 VanDerWaalsContact O-CD1 3.27Å; Q483-W487 PolarHBondContact O-N 3.48Å; Q483-W487 VanDerWaalsContact O-N 3.09Å; W487-L489 VanDerWaalsContact C-N 3.34Å; W487-M490 HydrophobicContact CE3-CB 4.31Å; W487-M490 PolarHBondContact O-N 3.48Å; W487-V491 WeakPolarHBondContact O-CB 3.25Å; W487-V491 WeakPolarHBondContact O-CG2 3.35Å; W487-V491 PolarHBondContact O-N 2.94Å; W487-I544 HydrophobicContact CB-CD1 3.37Å; W487-I544 HydrophobicContact CG-CD1 4.03Å
488	G	96.3	Very high	94.9	Very high	0 Å²	0	43.3 Å²	43.3	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-60.3	-43.2	171.8	0	0	0	0	0	112.6	G484 F486 G492	G484-G488 PolarHBondContact O-N 3.38Å; F486-G488 VanDerWaalsContact C-N 3.34Å; F486-G488 PolarHBondContact O-N 2.91Å; G488-G492 PolarHBondContact O-N 3.32Å
489	L	95.4	Very high	94.8	Very high	1 Å²	1	39.3 Å²	39.3	1%	0.005	19%	0.192	C	C	.	.	H	α-helix	trans	-66.7	-41.9	174.3	-75.2	164.1	0	0	0	112.6	L141 Y144 L145 P466 I467 V470 A485 F486 W487 G492 L493	L141-L489 HydrophobicContact CD1-CD1 3.3Å; Y144-L489 HydrophobicContact CD1-CB 4.38Å; Y144-L489 HydrophobicContact CD1-CD1 4.12Å; Y144-L489 HydrophobicContact CE1-CB 3.59Å; Y144-L489 HydrophobicContact CE1-CD1 3.85Å; Y144-L489 HydrophobicContact CE1-CD2 4.19Å; Y144-L489 HydrophobicContact CE1-CG 4.07Å; Y144-L489 PolarHBondContact OH-O 3.3Å; L145-L489 HydrophobicContact CD2-CD1 4.06Å; L145-L489 HydrophobicContact CD2-CD2 4.42Å; L145-L489 HydrophobicContact CG-CD1 4.45Å; P466-L489 HydrophobicContact CB-CD2 4.04Å; P466-L489 WeakPolarHBondContact O-CD2 3.34Å; I467-L489 HydrophobicContact CG1-CD2 4.23Å; V470-L489 HydrophobicContact CB-CD1 4.43Å; V470-L489 HydrophobicContact CB-CD2 4.38Å; V470-L489 HydrophobicContact CB-CG 4.42Å; V470-L489 HydrophobicContact CG1-CD1 4.39Å; V470-L489 HydrophobicContact CG2-CD1 3.95Å; V470-L489 HydrophobicContact CG2-CD2 3.89Å; V470-L489 HydrophobicContact CG2-CG 3.61Å; A485-L489 WeakPolarHBondContact O-CD1 3.46Å; A485-L489 WeakPolarHBondContact O-CG 3.33Å; A485-L489 PolarHBondContact O-N 2.83Å; F486-L489 PolarHBondContact O-N 3.43Å; W487-L489 VanDerWaalsContact C-N 3.34Å; L489-G492 PolarHBondContact O-N 3.33Å; L489-L493 VanDerWaalsContact O-CB 3.27Å; L489-L493 WeakPolarHBondContact O-CB 3.44Å; L489-L493 PolarHBondContact O-N 2.7Å
490	M	95.6	Very high	94.6	Very high	70 Å²	70	36.7 Å²	36.7	35%	0.345	18%	0.183	S	C	.	.	H	α-helix	trans	-63.9	-44.5	179.3	-72.4	-56.5	-57.1	0	0	112.3	Y144 F486 W487 L493 A494	Y144-M490 HydrophobicContact CD2-SD 3.83Å; Y144-M490 HydrophobicContact CE2-SD 3.54Å; Y144-M490 VanDerWaalsContact CE2-SD 3.54Å; F486-M490 HydrophobicContact CD1-CG 4.26Å; F486-M490 HydrophobicContact CE1-CG 3.83Å; F486-M490 HydrophobicContact CE2-CG 4.22Å; F486-M490 HydrophobicContact CE2-SD 4.42Å; F486-M490 HydrophobicContact CZ-CG 3.81Å; F486-M490 HydrophobicContact CZ-SD 4.19Å; F486-M490 WeakPolarHBondContact O-CG 3.03Å; F486-M490 PolarHBondContact O-N 3.05Å; W487-M490 HydrophobicContact CE3-CB 4.31Å; W487-M490 PolarHBondContact O-N 3.48Å; M490-L493 PolarHBondContact O-N 2.72Å; M490-A494 WeakPolarHBondContact O-CB 3.4Å; M490-A494 PolarHBondContact O-N 3.2Å
491	V	96.5	Very high	94.3	Very high	57 Å²	57	41 Å²	41	35%	0.345	21%	0.205	S	C	.	.	H	α-helix	trans	-65.4	-45	176.1	173	0	0	0	0	110.4	W487 L493 A494 M495 V540	W487-V491 WeakPolarHBondContact O-CB 3.25Å; W487-V491 WeakPolarHBondContact O-CG2 3.35Å; W487-V491 PolarHBondContact O-N 2.94Å; V491-L493 PolarHBondContact O-N 3.27Å; V491-A494 PolarHBondContact O-N 3.47Å; V491-M495 HydrophobicContact CG1-SD 4.05Å; V491-M495 WeakPolarHBondContact O-CG 3.47Å; V491-M495 PolarHBondContact O-N 3.22Å; V491-V540 HydrophobicContact CG1-CG2 4.26Å; V491-V540 HydrophobicContact CG2-CG1 4.31Å
492	G	96.5	Very high	94.1	Very high	0 Å²	0	41.6 Å²	41.6	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-59.9	-43.7	175.8	0	0	0	0	0	112.7	G488 L489 M495 G496 L533	G488-G492 PolarHBondContact O-N 3.32Å; L489-G492 PolarHBondContact O-N 3.33Å; G492-M495 PolarHBondContact O-N 2.88Å; G492-G496 PolarHBondContact O-N 2.88Å; G492-L533 WeakPolarHBondContact O-CD1 3.47Å
493	L	94.9	Very high	93.6	Very high	29 Å²	29	41.3 Å²	41.3	15%	0.152	21%	0.208	C	C	.	.	H	α-helix	trans	-63.6	-43.7	176.1	180	66	0	0	0	111.7	Y144 L148 L463 L489 M490 V491 M495 G496 L497	Y144-L493 HydrophobicContact CE2-CD2 3.64Å; Y144-L493 VanDerWaalsContact OH-CB 3.28Å; Y144-L493 WeakPolarHBondContact OH-CB 3.36Å; Y144-L493 WeakPolarHBondContact OH-CD2 3.49Å; L148-L493 HydrophobicContact CD1-CD1 3.74Å; L148-L493 HydrophobicContact CD2-CD1 4.35Å; L463-L493 HydrophobicContact CD2-CD1 3.98Å; L489-L493 VanDerWaalsContact O-CB 3.27Å; L489-L493 WeakPolarHBondContact O-CB 3.44Å; L489-L493 PolarHBondContact O-N 2.7Å; M490-L493 PolarHBondContact O-N 2.72Å; V491-L493 PolarHBondContact O-N 3.27Å; L493-M495 PolarHBondContact O-N 3.41Å; L493-G496 PolarHBondContact O-N 2.95Å; L493-L497 HydrophobicContact CD1-CD1 3.91Å; L493-L497 HydrophobicContact CD1-CD2 4.35Å; L493-L497 HydrophobicContact CD1-CG 3.82Å; L493-L497 HydrophobicContact CD2-CD1 4.34Å; L493-L497 HydrophobicContact CG-CD1 3.81Å; L493-L497 HydrophobicContact CG-CG 4.11Å; L493-L497 VanDerWaalsContact O-CB 3.32Å; L493-L497 WeakPolarHBondContact O-CB 3.48Å; L493-L497 VanDerWaalsContact O-CG 3.29Å; L493-L497 WeakPolarHBondContact O-CG 3.47Å; L493-L497 PolarHBondContact O-N 3.43Å
494	A	95.8	Very high	93.1	Very high	48 Å²	48	39.6 Å²	39.6	40%	0.397	20%	0.199	S	C	.	.	H	α-helix	trans	-59.8	-47.4	176.7	0	0	0	0	0	111.1	M490 V491 G496 L497 I498	M490-A494 WeakPolarHBondContact O-CB 3.4Å; M490-A494 PolarHBondContact O-N 3.2Å; V491-A494 PolarHBondContact O-N 3.47Å; A494-G496 PolarHBondContact O-N 3.45Å; A494-L497 PolarHBondContact O-N 3.06Å; A494-I498 WeakPolarHBondContact O-CB 3.34Å; A494-I498 WeakPolarHBondContact O-CD1 3.43Å; A494-I498 WeakPolarHBondContact O-CG1 3.4Å; A494-I498 PolarHBondContact O-N 3.45Å
495	M	95.3	Very high	92.6	Very high	67 Å²	67	44.5 Å²	44.5	33%	0.33	23%	0.229	S	C	.	.	H	α-helix	trans	-60.4	-45.6	176.2	-70.3	175.4	63.1	0	0	112.1	V491 G492 L493 I498 R499 L533	V491-M495 HydrophobicContact CG1-SD 4.05Å; V491-M495 WeakPolarHBondContact O-CG 3.47Å; V491-M495 PolarHBondContact O-N 3.22Å; G492-M495 PolarHBondContact O-N 2.88Å; L493-M495 PolarHBondContact O-N 3.41Å; M495-I498 PolarHBondContact O-N 3.08Å; M495-R499 PolarHBondContact O-N 3.12Å; M495-R499 VanDerWaalsContact O-N 3.13Å; M495-L533 HydrophobicContact CB-CD1 3.69Å; M495-L533 HydrophobicContact CE-CD1 4.21Å; M495-L533 HydrophobicContact SD-CD1 4.34Å
496	G	94.9	Very high	92	Very high	0 Å²	0	50 Å²	50	0%	0	25%	0.25	C	S	.	.	H	α-helix	trans	-62.6	-48	178.2	0	0	0	0	0	113.1	Y462 G492 L493 A494 I498 R499 M500	Y462-G496 WeakPolarHBondContact O-CA 3.26Å; G492-G496 PolarHBondContact O-N 2.88Å; L493-G496 PolarHBondContact O-N 2.95Å; A494-G496 PolarHBondContact O-N 3.45Å; G496-I498 PolarHBondContact O-N 2.92Å; G496-R499 PolarHBondContact O-N 2.97Å; G496-M500 VanDerWaalsContact O-CB 3.3Å; G496-M500 WeakPolarHBondContact O-CB 3.45Å; G496-M500 PolarHBondContact O-N 3.18Å
497	L	93.1	Very high	91	Very high	51 Å²	51	49.6 Å²	49.6	27%	0.267	26%	0.258	S	S	.	.	H	α-helix	trans	-64.7	-39.1	177.8	-72	179.1	0	0	0	112	L463 L493 A494 R499 M500 I501	L463-L497 HydrophobicContact CD2-CD2 4.1Å; L493-L497 HydrophobicContact CD1-CD1 3.91Å; L493-L497 HydrophobicContact CD1-CD2 4.35Å; L493-L497 HydrophobicContact CD1-CG 3.82Å; L493-L497 HydrophobicContact CD2-CD1 4.34Å; L493-L497 HydrophobicContact CG-CD1 3.81Å; L493-L497 HydrophobicContact CG-CG 4.11Å; L493-L497 VanDerWaalsContact O-CB 3.32Å; L493-L497 WeakPolarHBondContact O-CB 3.48Å; L493-L497 VanDerWaalsContact O-CG 3.29Å; L493-L497 WeakPolarHBondContact O-CG 3.47Å; L493-L497 PolarHBondContact O-N 3.43Å; A494-L497 PolarHBondContact O-N 3.06Å; L497-R499 VanDerWaalsContact C-N 3.34Å; L497-R499 PolarHBondContact O-N 2.78Å; L497-M500 HydrophobicContact CD2-CE 3.52Å; L497-M500 HydrophobicContact CD2-SD 4.47Å; L497-M500 PolarHBondContact O-N 3.49Å; L497-I501 HydrophobicContact CB-CD1 4.32Å; L497-I501 VanDerWaalsContact O-CB 3.25Å; L497-I501 WeakPolarHBondContact O-CB 3.13Å; L497-I501 WeakPolarHBondContact O-CD1 3.3Å; L497-I501 WeakPolarHBondContact O-CG1 3.15Å; L497-I501 PolarHBondContact O-N 3.02Å
498	I	92.8	Very high	89.9	Confident	100 Å²	100	45 Å²	45	51%	0.513	24%	0.244	S	C	.	.	H	α-helix	trans	-59.3	-48	174.6	-71.4	163.4	0	0	0	109.8	A494 M495 G496 T502	A494-I498 WeakPolarHBondContact O-CB 3.34Å; A494-I498 WeakPolarHBondContact O-CD1 3.43Å; A494-I498 WeakPolarHBondContact O-CG1 3.4Å; A494-I498 PolarHBondContact O-N 3.45Å; M495-I498 PolarHBondContact O-N 3.08Å; G496-I498 PolarHBondContact O-N 2.92Å; I498-T502 VanDerWaalsContact O-CB 3.25Å; I498-T502 WeakPolarHBondContact O-CB 3.36Å; I498-T502 PolarHBondContact O-N 3.23Å; I498-T502 PolarHBondContact O-OG1 3.13Å
499	R	91.4	Very high	88.7	Confident	10 Å²	10	49.6 Å²	49.6	4%	0.038	27%	0.274	C	S	.	.	H	α-helix	trans	-61.1	-46.3	177.7	179.7	68.2	-177.1	83.2	4.4	112	Y462 M495 G496 L497 E503 I521 F529	Y462-R499 HydrophobicContact CD1-CB 4.37Å; Y462-R499 HydrophobicContact CD1-CG 3.66Å; Y462-R499 HydrophobicContact CE1-CG 3.49Å; Y462-R499 VanDerWaalsContact CE1-CG 3.49Å; Y462-R499 HydrophobicContact CG-CG 4.3Å; Y462-R499 PolarHBondContact OH-NH2 3.49Å; M495-R499 PolarHBondContact O-N 3.12Å; M495-R499 VanDerWaalsContact O-N 3.13Å; G496-R499 PolarHBondContact O-N 2.97Å; L497-R499 VanDerWaalsContact C-N 3.34Å; L497-R499 PolarHBondContact O-N 2.78Å; R499-E503 IonicContact CZ-OE2 3.32Å; R499-E503 IonicContact NH1-OE2 2.81Å; R499-E503 PolarHBondContact NH1-OE2 3.14Å; R499-E503 IonicContact NH2-OE2 2.61Å; R499-E503 PolarHBondContact NH2-OE2 2.76Å; R499-E503 PolarHBondContact O-N 3.45Å; R499-I521 WeakPolarHBondContact CD-O 3.5Å; R499-I521 PolarHBondContact NE-O 3.39Å; R499-I521 VanDerWaalsContact NE-O 3.08Å; R499-F529 HydrophobicContact CB-CE1 3.79Å; R499-F529 HydrophobicContact CB-CE2 3.86Å; R499-F529 HydrophobicContact CB-CZ 3.41Å; R499-F529 VanDerWaalsContact CB-CZ 3.41Å; R499-F529 HydrophobicContact CG-CD1 4.06Å; R499-F529 HydrophobicContact CG-CD2 4.15Å; R499-F529 HydrophobicContact CG-CE1 3.82Å; R499-F529 HydrophobicContact CG-CE2 3.94Å; R499-F529 HydrophobicContact CG-CG 4.2Å; R499-F529 HydrophobicContact CG-CZ 3.77Å
500	M	90	Very high	87.7	Confident	13 Å²	13	51.4 Å²	51.4	6%	0.064	29%	0.288	C	S	.	.	H	α-helix	trans	-65.3	-51.6	-178.2	-175.3	-172.7	81.4	0	0	111.9	F151 Y462 L463 G496 L497 T502 E503 F504	F151-M500 HydrophobicContact CZ-CE 4.32Å; Y462-M500 HydrophobicContact CD2-CB 3.8Å; Y462-M500 HydrophobicContact CD2-CG 4.07Å; Y462-M500 HydrophobicContact CG-CB 4.34Å; L463-M500 HydrophobicContact CD1-SD 4.18Å; G496-M500 VanDerWaalsContact O-CB 3.3Å; G496-M500 WeakPolarHBondContact O-CB 3.45Å; G496-M500 PolarHBondContact O-N 3.18Å; L497-M500 HydrophobicContact CD2-CE 3.52Å; L497-M500 HydrophobicContact CD2-SD 4.47Å; L497-M500 PolarHBondContact O-N 3.49Å; M500-T502 VanDerWaalsContact C-N 3.3Å; M500-T502 PolarHBondContact O-N 2.96Å; M500-E503 PolarHBondContact O-N 2.91Å; M500-F504 HydrophobicContact CE-CE2 4.3Å; M500-F504 HydrophobicContact CG-CD2 3.71Å; M500-F504 HydrophobicContact CG-CE2 3.37Å; M500-F504 HydrophobicContact CG-CZ 4.47Å; M500-F504 WeakPolarHBondContact O-CD2 3.37Å; M500-F504 PolarHBondContact O-N 3.29Å; M500-F504 HydrophobicContact SD-CE2 3.97Å
501	I	89.7	Confident	86.7	Confident	92 Å²	92	51.3 Å²	51.3	47%	0.472	29%	0.293	S	S	.	.	H	α-helix	trans	-61.8	-41.6	179.2	-67	166.5	0	0	0	110.1	L497 E503 F504 V505	L497-I501 HydrophobicContact CB-CD1 4.32Å; L497-I501 VanDerWaalsContact O-CB 3.25Å; L497-I501 WeakPolarHBondContact O-CB 3.13Å; L497-I501 WeakPolarHBondContact O-CD1 3.3Å; L497-I501 WeakPolarHBondContact O-CG1 3.15Å; L497-I501 PolarHBondContact O-N 3.02Å; I501-E503 VanDerWaalsContact C-N 3.34Å; I501-E503 PolarHBondContact O-N 3.48Å; I501-F504 PolarHBondContact O-N 2.93Å; I501-V505 HydrophobicContact CG2-CG2 4.06Å; I501-V505 WeakPolarHBondContact O-CB 3.35Å; I501-V505 WeakPolarHBondContact O-CG2 3.36Å; I501-V505 PolarHBondContact O-N 3.42Å
502	T	88.3	Confident	85.5	Confident	21 Å²	21	51.5 Å²	51.5	13%	0.129	29%	0.292	C	S	.	.	H	α-helix	trans	-62.5	-43.2	177.4	-53	0	0	0	0	110.9	I498 M500 F504 V505 Y506 C517 I521	I498-T502 VanDerWaalsContact O-CB 3.25Å; I498-T502 WeakPolarHBondContact O-CB 3.36Å; I498-T502 PolarHBondContact O-N 3.23Å; I498-T502 PolarHBondContact O-OG1 3.13Å; M500-T502 VanDerWaalsContact C-N 3.3Å; M500-T502 PolarHBondContact O-N 2.96Å; T502-F504 PolarHBondContact O-N 3.27Å; T502-V505 PolarHBondContact O-N 2.84Å; T502-Y506 HydrophobicContact CG2-CD2 3.59Å; T502-Y506 HydrophobicContact CG2-CE2 3.86Å; T502-Y506 VanDerWaalsContact O-CD2 3.32Å; T502-Y506 WeakPolarHBondContact O-CD2 3.25Å; T502-Y506 PolarHBondContact O-N 2.77Å; T502-C517 WeakPolarHBondContact CG2-SG 3.49Å; T502-I521 HydrophobicContact CG2-CB 4.43Å; T502-I521 HydrophobicContact CG2-CD1 4.34Å; T502-I521 HydrophobicContact CG2-CG2 3.9Å
503	E	83.9	Confident	84.2	Confident	30 Å²	30	54.2 Å²	54.2	14%	0.14	31%	0.314	C	S	.	.	H	α-helix	trans	-62.6	-42.7	176.4	-169.2	153.5	128.5	0	0	112.6	Y462 R499 M500 I501 G507 T508	Y462-E503 VanDerWaalsContact OH-CD 3.3Å; Y462-E503 PolarHBondContact OH-OE1 3.49Å; Y462-E503 PolarHBondContact OH-OE2 3.11Å; R499-E503 IonicContact CZ-OE2 3.32Å; R499-E503 IonicContact NH1-OE2 2.81Å; R499-E503 PolarHBondContact NH1-OE2 3.14Å; R499-E503 IonicContact NH2-OE2 2.61Å; R499-E503 PolarHBondContact NH2-OE2 2.76Å; R499-E503 PolarHBondContact O-N 3.45Å; M500-E503 PolarHBondContact O-N 2.91Å; I501-E503 VanDerWaalsContact C-N 3.34Å; I501-E503 PolarHBondContact O-N 3.48Å; E503-G507 CarbonylContact O-C 3.09Å; E503-G507 VanDerWaalsContact O-CA 3.23Å; E503-G507 WeakPolarHBondContact O-CA 3.32Å; E503-G507 PolarHBondContact O-N 3.01Å; E503-T508 VanDerWaalsContact CD-CG2 3.41Å; E503-T508 HydrophobicContact CG-CG2 3.55Å; E503-T508 WeakPolarHBondContact OE1-CG2 3.47Å
504	F	83.4	Confident	83	Confident	64 Å²	64	58.8 Å²	58.8	28%	0.281	34%	0.344	S	S	.	.	H	α-helix	trans	-66.3	-38.5	177	-76.8	-58.2	0	0	0	113.2	S447 Y455 I459 M500 I501 T502	S447-F504 VanDerWaalsContact CB-CE1 3.46Å; Y455-F504 HydrophobicContact CE2-CE1 4.03Å; Y455-F504 HydrophobicContact CE2-CZ 4.12Å; I459-F504 HydrophobicContact CD1-CZ 4.11Å; M500-F504 HydrophobicContact CE-CE2 4.3Å; M500-F504 HydrophobicContact CG-CD2 3.71Å; M500-F504 HydrophobicContact CG-CE2 3.37Å; M500-F504 HydrophobicContact CG-CZ 4.47Å; M500-F504 WeakPolarHBondContact O-CD2 3.37Å; M500-F504 PolarHBondContact O-N 3.29Å; M500-F504 HydrophobicContact SD-CE2 3.97Å; I501-F504 PolarHBondContact O-N 2.93Å; T502-F504 PolarHBondContact O-N 3.27Å
505	V	85.1	Confident	81.9	Confident	103 Å²	103	58 Å²	58	62%	0.624	34%	0.335	S	S	*	.	H	α-helix	trans	-72.8	-42.2	-177.8	169.1	0	0	0	0	111.8	I501 T502	I501-V505 HydrophobicContact CG2-CG2 4.06Å; I501-V505 WeakPolarHBondContact O-CB 3.35Å; I501-V505 WeakPolarHBondContact O-CG2 3.36Å; I501-V505 PolarHBondContact O-N 3.42Å; T502-V505 PolarHBondContact O-N 2.84Å
506	Y	82.6	Confident	81	Confident	115 Å²	115	61.3 Å²	61.3	45%	0.451	35%	0.354	S	S	.	.	H	α-helix	trans	-91	-9.4	-177.8	-71.7	-81.9	0	0	0	113.5	T502 S515 N516 C517	T502-Y506 HydrophobicContact CG2-CD2 3.59Å; T502-Y506 HydrophobicContact CG2-CE2 3.86Å; T502-Y506 VanDerWaalsContact O-CD2 3.32Å; T502-Y506 WeakPolarHBondContact O-CD2 3.25Å; T502-Y506 PolarHBondContact O-N 2.77Å; Y506-S515 PolarHBondContact O-OG 3.37Å; Y506-N516 HydrophobicContact CD1-CB 4.45Å; Y506-C517 HydrophobicContact CD2-CB 4.49Å; Y506-C517 HydrophobicContact CG-CB 4.1Å
507	G	74.3	Confident	80.3	Confident	32 Å²	32	62 Å²	62	33%	0.33	36%	0.358	S	S	.	.			trans	70.8	154.8	-172.6	0	0	0	0	0	112.5	E503 S515	E503-G507 CarbonylContact O-C 3.09Å; E503-G507 VanDerWaalsContact O-CA 3.23Å; E503-G507 WeakPolarHBondContact O-CA 3.32Å; E503-G507 PolarHBondContact O-N 3.01Å; G507-S515 VanDerWaalsContact O-CB 3.22Å; G507-S515 WeakPolarHBondContact O-CB 3.38Å; G507-S515 PolarHBondContact O-OG 3.27Å
508	T	71.3	Confident	79.8	Confident	41 Å²	41	62 Å²	62	25%	0.252	36%	0.362	S	S	.	.			trans	-77.9	143.4	167.4	29.4	0	0	0	0	109.8	N449 E503 S510	N449-T508 WeakPolarHBondContact ND2-CB 3.28Å; N449-T508 PolarHBondContact ND2-O 3.1Å; N449-T508 PolarHBondContact ND2-OG1 2.95Å; N449-T508 PolarHBondContact OD1-OG1 3.09Å; E503-T508 VanDerWaalsContact CD-CG2 3.41Å; E503-T508 HydrophobicContact CG-CG2 3.55Å; E503-T508 WeakPolarHBondContact OE1-CG2 3.47Å; T508-S510 PolarHBondContact O-N 3.42Å
509	P	72.5	Confident	79.2	Confident	97 Å²	97	66.1 Å²	66.1	63%	0.63	38%	0.376	S	S	*	.			trans	-53.8	134	172.1	-19.5	28.6	0	0	0	110.2	N449	N449-P509 PolarHBondContact ND2-O 3.35Å
510	S	73.9	Confident	78.6	Confident	40 Å²	40	73.1 Å²	73.1	28%	0.28	41%	0.412	S	S	.	.			trans	-125.1	171.5	172.2	75.2	0	0	0	0	109.7	T508 L512 A513	T508-S510 PolarHBondContact O-N 3.42Å; S510-L512 PolarHBondContact O-N 3.46Å; S510-L512 PolarHBondContact OG-N 3.05Å; S510-A513 PolarHBondContact N-O 3.04Å; S510-A513 PolarHBondContact O-N 2.92Å; S510-A513 VanDerWaalsContact O-O 3.08Å; S510-A513 PolarHBondContact OG-N 3.23Å
511	C	74.7	Confident	78	Confident	68 Å²	68	75 Å²	75	46%	0.459	42%	0.422	S	S	.	.	S	Bend	trans	-63.8	-18.1	173.1	-74.1	0	0	0	0	113.7	C255	C255-C511 HydrophobicContact CB-CB 3.68Å; C255-C511 WeakPolarHBondContact CB-SG 3.46Å; C255-C511 VanDerWaalsContact SG-CA 3.57Å; C255-C511 WeakPolarHBondContact SG-CB 3.49Å; C255-C511 CovalentContact SG-SG 2.02Å; C255-C511 PolarHBondContact SG-SG 3.27Å
512	L	70.8	Confident	77.4	Confident	60 Å²	60	72.1 Å²	72.1	31%	0.314	41%	0.41	S	S	.	.	S	Bend	trans	-100.1	-29.7	-178.5	-63.7	167.6	0	0	0	112.5	L249 I251 P348 D358 S510	L249-L512 HydrophobicContact CD1-CD2 4.21Å; I251-L512 HydrophobicContact CD1-CD2 3.67Å; P348-L512 HydrophobicContact CG-CD1 3.85Å; P348-L512 HydrophobicContact CG-CD2 3.51Å; P348-L512 HydrophobicContact CG-CG 4.34Å; D358-L512 WeakPolarHBondContact O-CD1 2.93Å; S510-L512 PolarHBondContact O-N 3.46Å; S510-L512 PolarHBondContact OG-N 3.05Å
513	A	68.9	Low	77.1	Confident	58 Å²	58	73.9 Å²	73.9	48%	0.479	43%	0.432	S	S	.	.			trans	-140.3	129.8	-174.3	0	0	0	0	0	111.6	S510	S510-A513 PolarHBondContact N-O 3.04Å; S510-A513 PolarHBondContact O-N 2.92Å; S510-A513 VanDerWaalsContact O-O 3.08Å; S510-A513 PolarHBondContact OG-N 3.23Å
514	T	69.6	Low	77.4	Confident	125 Å²	125	74.6 Å²	74.6	77%	0.767	44%	0.439	S	S	*	.			trans	-80.2	135.5	170	52.4	0	0	0	0	109.7
515	S	73.6	Confident	77.8	Confident	30 Å²	30	73.7 Å²	73.7	21%	0.21	44%	0.435	C	S	.	.			trans	-78.5	133	175	-179.8	0	0	0	0	110.2	Y506 G507 C517	Y506-S515 PolarHBondContact O-OG 3.37Å; G507-S515 VanDerWaalsContact O-CB 3.22Å; G507-S515 WeakPolarHBondContact O-CB 3.38Å; G507-S515 PolarHBondContact O-OG 3.27Å; S515-C517 PolarHBondContact O-N 3.48Å; S515-C517 WeakPolarHBondContact OG-CB 3.3Å; S515-C517 PolarHBondContact OG-N 2.96Å
516	N	77.2	Confident	78.2	Confident	137 Å²	137	69.5 Å²	69.5	73%	0.733	41%	0.408	S	S	*	.			trans	-84.6	13.9	171.5	-73.5	-40.1	0	0	0	112.7	Y506	Y506-N516 HydrophobicContact CD1-CB 4.45Å
517	C	79.8	Confident	78.8	Confident	14 Å²	14	64 Å²	64	10%	0.095	39%	0.387	C	S	.	.			trans	-61.2	135	-178	-174.8	0	0	0	0	111.6	T502 Y506 S515 K519 C522	T502-C517 WeakPolarHBondContact CG2-SG 3.49Å; Y506-C517 HydrophobicContact CD2-CB 4.49Å; Y506-C517 HydrophobicContact CG-CB 4.1Å; S515-C517 PolarHBondContact O-N 3.48Å; S515-C517 WeakPolarHBondContact OG-CB 3.3Å; S515-C517 PolarHBondContact OG-N 2.96Å; C517-K519 PolarHBondContact O-N 3.1Å; C517-C522 HydrophobicContact CB-CB 3.47Å; C517-C522 VanDerWaalsContact CB-CB 3.47Å; C517-C522 WeakPolarHBondContact CB-SG 3.3Å; C517-C522 WeakPolarHBondContact SG-CB 3.41Å; C517-C522 CovalentContact SG-SG 2Å; C517-C522 PolarHBondContact SG-SG 2.89Å
518	P	82.3	Confident	79.8	Confident	53 Å²	53	65.2 Å²	65.2	34%	0.344	38%	0.382	S	S	.	.			trans	-51.8	124.3	175.6	-28.1	34.6	0	0	0	112.2	I520 I521 C522	P518-I520 PolarHBondContact O-N 2.58Å; P518-I521 PolarHBondContact O-N 3.2Å; P518-C522 PolarHBondContact O-N 3.29Å
519	K	79.9	Confident	80.9	Confident	186 Å²	186	64.4 Å²	64.4	81%	0.809	38%	0.375	S	S	*	.	H	α-helix	trans	-55.2	-27.3	-178.8	-69.4	-172.3	178.1	-177.1	0	113.5	C517 I521 G523	C517-K519 PolarHBondContact O-N 3.1Å; K519-I521 VanDerWaalsContact C-N 3.29Å; K519-I521 PolarHBondContact O-N 3.42Å; K519-G523 WeakPolarHBondContact O-CA 3.41Å; K519-G523 PolarHBondContact O-N 2.92Å
520	I	78.5	Confident	82.1	Confident	156 Å²	156	59.8 Å²	59.8	80%	0.8	35%	0.345	S	S	*	.	H	α-helix	trans	-70.3	-26.2	178.8	-143.8	164.5	0	0	0	112.7	P518	P518-I520 PolarHBondContact O-N 2.58Å
521	I	77.6	Confident	83.2	Confident	53 Å²	53	59.5 Å²	59.5	27%	0.272	34%	0.34	S	S	.	.	H	α-helix	trans	-100.6	-53.6	-179.7	-60.5	172.4	0	0	0	110.3	R499 T502 P518 K519	R499-I521 WeakPolarHBondContact CD-O 3.5Å; R499-I521 PolarHBondContact NE-O 3.39Å; R499-I521 VanDerWaalsContact NE-O 3.08Å; T502-I521 HydrophobicContact CG2-CB 4.43Å; T502-I521 HydrophobicContact CG2-CD1 4.34Å; T502-I521 HydrophobicContact CG2-CG2 3.9Å; P518-I521 PolarHBondContact O-N 3.2Å; K519-I521 VanDerWaalsContact C-N 3.29Å; K519-I521 PolarHBondContact O-N 3.42Å
522	C	78.1	Confident	84.2	Confident	32 Å²	32	60.6 Å²	60.6	22%	0.216	34%	0.34	C	S	.	.	H	α-helix	trans	-95.7	-7.6	-175.9	-61.9	0	0	0	0	114.9	C517 P518 V524	C517-C522 HydrophobicContact CB-CB 3.47Å; C517-C522 VanDerWaalsContact CB-CB 3.47Å; C517-C522 WeakPolarHBondContact CB-SG 3.3Å; C517-C522 WeakPolarHBondContact SG-CB 3.41Å; C517-C522 CovalentContact SG-SG 2Å; C517-C522 PolarHBondContact SG-SG 2.89Å; P518-C522 PolarHBondContact O-N 3.29Å; C522-V524 PolarHBondContact O-N 3.22Å
523	G	81.8	Confident	85.5	Confident	57 Å²	57	57.8 Å²	57.8	59%	0.588	33%	0.325	S	S	*	.	S	Bend	trans	-73.6	-8	179.6	0	0	0	0	0	113.9	K519	K519-G523 WeakPolarHBondContact O-CA 3.41Å; K519-G523 PolarHBondContact O-N 2.92Å
524	V	89.6	Confident	86.9	Confident	46 Å²	46	55.8 Å²	55.8	28%	0.279	31%	0.306	S	S	.	.	S	Bend	trans	-97.4	123.3	176.5	-176.9	0	0	0	0	109.3	C522 F529 I532	C522-V524 PolarHBondContact O-N 3.22Å; V524-F529 HydrophobicContact CG1-CB 4.35Å; V524-I532 HydrophobicContact CG1-CD1 4.23Å
525	H	91.9	Very high	88.2	Confident	45 Å²	45	55.3 Å²	55.3	21%	0.208	29%	0.293	C	S	.	.			trans	-54.9	141.1	174.6	-169.6	-90.5	0	0	0	111	D273 P275 L527 Y528 F529	D273-H525 PolarHBondContact O-NE2 3.25Å; P275-H525 HydrophobicContact CG-CB 4.35Å; H525-L527 PolarHBondContact ND1-N 3.4Å; H525-L527 PolarHBondContact O-N 3.42Å; H525-L527 VanDerWaalsContact O-N 3.15Å; H525-Y528 HydrophobicContact CB-CD2 3.77Å; H525-Y528 HydrophobicContact CB-CE2 4.3Å; H525-Y528 HydrophobicContact CB-CG 4.48Å; H525-Y528 WeakPolarHBondContact O-CB 3.17Å; H525-Y528 PolarHBondContact O-N 3.47Å; H525-F529 PolarHBondContact O-N 2.86Å
526	Y	92.8	Very high	89.4	Confident	15 Å²	15	55 Å²	55	6%	0.059	29%	0.294	C	S	.	.	H	α-helix	trans	-58.9	-32.9	-172.7	61.4	-97.7	0	0	0	113.2	F101 H454 E457 S461 F529 S530	F101-Y526 WeakPolarHBondContact CZ-OH 3.28Å; H454-Y526 AromaticContact ND1-CE1 3.94Å; H454-Y526 AromaticContact ND1-CZ 3.93Å; H454-Y526 PolarHBondContact ND1-OH 2.93Å; E457-Y526 HydrophobicContact CB-CE2 3.87Å; S461-Y526 WeakPolarHBondContact CB-O 3.44Å; S461-Y526 WeakPolarHBondContact OG-CD2 3.38Å; Y526-F529 WeakPolarHBondContact O-CB 3.48Å; Y526-F529 PolarHBondContact O-N 3.46Å; Y526-S530 PolarHBondContact O-N 3.3Å
527	L	94.8	Very high	90.4	Very high	0 Å²	0	48.5 Å²	48.5	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-65.8	-36.8	173.8	-64.5	175.9	0	0	0	112.9	I274 G282 M283 H525 S530 I531	I274-L527 HydrophobicContact CG2-CD1 4.31Å; G282-L527 WeakPolarHBondContact CA-O 3.42Å; M283-L527 HydrophobicContact CB-CD2 4.21Å; H525-L527 PolarHBondContact ND1-N 3.4Å; H525-L527 PolarHBondContact O-N 3.42Å; H525-L527 VanDerWaalsContact O-N 3.15Å; L527-S530 WeakPolarHBondContact O-CB 3.33Å; L527-S530 PolarHBondContact O-N 3.27Å; L527-I531 WeakPolarHBondContact O-CG1 3.47Å; L527-I531 PolarHBondContact O-N 3.19Å
528	Y	95.6	Very high	91.2	Very high	56 Å²	56	49.5 Å²	49.5	22%	0.22	26%	0.263	C	S	.	.	H	α-helix	trans	-71.8	-38.3	173.4	-64.9	-38.7	0	0	0	111.7	P269 P275 P277 H525 S530 I531 I532	P269-Y528 WeakPolarHBondContact O-CE2 3.47Å; P269-Y528 PolarHBondContact O-OH 3.01Å; P275-Y528 HydrophobicContact CB-CE2 4.24Å; P275-Y528 WeakPolarHBondContact CB-OH 3.5Å; P275-Y528 HydrophobicContact CG-CE2 3.97Å; P277-Y528 HydrophobicContact CB-CE1 3.94Å; P277-Y528 VanDerWaalsContact CD-OH 3.25Å; P277-Y528 WeakPolarHBondContact CD-OH 3.38Å; P277-Y528 HydrophobicContact CG-CE1 4.22Å; P277-Y528 VanDerWaalsContact CG-OH 3.27Å; P277-Y528 WeakPolarHBondContact CG-OH 3.42Å; H525-Y528 HydrophobicContact CB-CD2 3.77Å; H525-Y528 HydrophobicContact CB-CE2 4.3Å; H525-Y528 HydrophobicContact CB-CG 4.48Å; H525-Y528 WeakPolarHBondContact O-CB 3.17Å; H525-Y528 PolarHBondContact O-N 3.47Å; Y528-S530 VanDerWaalsContact C-N 3.26Å; Y528-S530 PolarHBondContact O-N 2.98Å; Y528-I531 HydrophobicContact CD1-CD1 4.1Å; Y528-I531 WeakPolarHBondContact O-CB 3.46Å; Y528-I531 PolarHBondContact O-N 3.44Å; Y528-I531 VanDerWaalsContact O-N 3.16Å; Y528-I532 WeakPolarHBondContact O-CG1 3.42Å; Y528-I532 PolarHBondContact O-N 3.35Å; Y528-I532 VanDerWaalsContact O-N 3.07Å
529	F	95.3	Very high	92	Very high	25 Å²	25	53.1 Å²	53.1	11%	0.11	28%	0.279	C	S	.	.	H	α-helix	trans	-59.9	-39.1	173.2	-175.8	-95.3	0	0	0	111.4	Y462 R499 V524 H525 Y526 I531 I532 L533	Y462-F529 AromaticContact CD1-CD1 3.57Å; Y462-F529 HydrophobicContact CD1-CD1 3.57Å; Y462-F529 AromaticContact CD1-CE1 3.76Å; Y462-F529 HydrophobicContact CD1-CE1 3.76Å; Y462-F529 AromaticContact CE1-CD1 3.99Å; Y462-F529 HydrophobicContact CE1-CD1 3.99Å; Y462-F529 HydrophobicContact CE1-CE1 4.48Å; R499-F529 HydrophobicContact CB-CE1 3.79Å; R499-F529 HydrophobicContact CB-CE2 3.86Å; R499-F529 HydrophobicContact CB-CZ 3.41Å; R499-F529 VanDerWaalsContact CB-CZ 3.41Å; R499-F529 HydrophobicContact CG-CD1 4.06Å; R499-F529 HydrophobicContact CG-CD2 4.15Å; R499-F529 HydrophobicContact CG-CE1 3.82Å; R499-F529 HydrophobicContact CG-CE2 3.94Å; R499-F529 HydrophobicContact CG-CG 4.2Å; R499-F529 HydrophobicContact CG-CZ 3.77Å; V524-F529 HydrophobicContact CG1-CB 4.35Å; H525-F529 PolarHBondContact O-N 2.86Å; Y526-F529 WeakPolarHBondContact O-CB 3.48Å; Y526-F529 PolarHBondContact O-N 3.46Å; F529-I531 VanDerWaalsContact C-N 3.32Å; F529-I531 PolarHBondContact O-N 3.08Å; F529-I532 PolarHBondContact O-N 3.49Å; F529-L533 HydrophobicContact CD1-CB 4.48Å; F529-L533 HydrophobicContact CE1-CB 4.27Å; F529-L533 HydrophobicContact CE1-CD2 3.85Å; F529-L533 VanDerWaalsContact O-CB 3.22Å; F529-L533 WeakPolarHBondContact O-CB 3.37Å; F529-L533 PolarHBondContact O-N 3.42Å
530	S	96.8	Very high	92.9	Very high	0 Å²	0	46.2 Å²	46.2	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-55.5	-44.7	173.4	173.4	0	0	0	0	112.3	G282 P465 Y526 L527 Y528 L533 F534	G282-S530 PolarHBondContact O-OG 3.42Å; P465-S530 WeakPolarHBondContact CG-OG 3.26Å; Y526-S530 PolarHBondContact O-N 3.3Å; L527-S530 WeakPolarHBondContact O-CB 3.33Å; L527-S530 PolarHBondContact O-N 3.27Å; Y528-S530 VanDerWaalsContact C-N 3.26Å; Y528-S530 PolarHBondContact O-N 2.98Å; S530-L533 PolarHBondContact O-N 2.93Å; S530-F534 VanDerWaalsContact O-CB 3.28Å; S530-F534 WeakPolarHBondContact O-CB 3.35Å; S530-F534 PolarHBondContact O-N 3.05Å
531	I	97.3	Very high	93.8	Very high	33 Å²	33	38.8 Å²	38.8	17%	0.169	21%	0.214	C	C	.	.	H	α-helix	trans	-60.5	-52.2	176.1	-59.1	168.7	0	0	0	110.5	F281 G282 I285 L527 Y528 F529 L533 F534 F535	F281-I531 HydrophobicContact CB-CD1 3.55Å; F281-I531 HydrophobicContact CB-CG1 4.12Å; G282-I531 VanDerWaalsContact CA-CG1 3.42Å; I285-I531 HydrophobicContact CD1-CG1 4.24Å; L527-I531 WeakPolarHBondContact O-CG1 3.47Å; L527-I531 PolarHBondContact O-N 3.19Å; Y528-I531 HydrophobicContact CD1-CD1 4.1Å; Y528-I531 WeakPolarHBondContact O-CB 3.46Å; Y528-I531 PolarHBondContact O-N 3.44Å; Y528-I531 VanDerWaalsContact O-N 3.16Å; F529-I531 VanDerWaalsContact C-N 3.32Å; F529-I531 PolarHBondContact O-N 3.08Å; I531-L533 VanDerWaalsContact C-N 3.29Å; I531-L533 PolarHBondContact O-N 3.22Å; I531-F534 PolarHBondContact O-N 2.99Å; I531-F535 HydrophobicContact CG2-CD2 3.69Å; I531-F535 HydrophobicContact CG2-CE2 3.82Å; I531-F535 VanDerWaalsContact O-CD2 3.29Å; I531-F535 WeakPolarHBondContact O-CD2 3.24Å; I531-F535 PolarHBondContact O-N 3.17Å
532	I	96.5	Very high	94.7	Very high	92 Å²	92	38.7 Å²	38.7	47%	0.472	21%	0.214	S	C	.	.	H	α-helix	trans	-58.8	-45.6	-178.9	-65	166.1	0	0	0	110	V524 Y528 F529 G536	V524-I532 HydrophobicContact CG1-CD1 4.23Å; Y528-I532 WeakPolarHBondContact O-CG1 3.42Å; Y528-I532 PolarHBondContact O-N 3.35Å; Y528-I532 VanDerWaalsContact O-N 3.07Å; F529-I532 PolarHBondContact O-N 3.49Å; I532-G536 WeakPolarHBondContact O-CA 3.28Å; I532-G536 PolarHBondContact O-N 3.03Å
533	L	97.4	Very high	95.7	Very high	0 Å²	0	38.8 Å²	38.8	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-66.5	-41.6	-177.9	-174.1	61.7	0	0	0	112	Y462 P465 P466 G492 M495 F529 S530 I531 S537	Y462-L533 WeakPolarHBondContact O-CD2 3.38Å; P465-L533 HydrophobicContact CB-CB 4.17Å; P465-L533 HydrophobicContact CB-CD2 4.13Å; P465-L533 HydrophobicContact CB-CG 4.13Å; P465-L533 HydrophobicContact CG-CD2 4.17Å; P466-L533 HydrophobicContact CG-CD1 4.13Å; P466-L533 HydrophobicContact CG-CD2 3.81Å; P466-L533 HydrophobicContact CG-CG 3.79Å; G492-L533 WeakPolarHBondContact O-CD1 3.47Å; M495-L533 HydrophobicContact CB-CD1 3.69Å; M495-L533 HydrophobicContact CE-CD1 4.21Å; M495-L533 HydrophobicContact SD-CD1 4.34Å; F529-L533 HydrophobicContact CD1-CB 4.48Å; F529-L533 HydrophobicContact CE1-CB 4.27Å; F529-L533 HydrophobicContact CE1-CD2 3.85Å; F529-L533 VanDerWaalsContact O-CB 3.22Å; F529-L533 WeakPolarHBondContact O-CB 3.37Å; F529-L533 PolarHBondContact O-N 3.42Å; S530-L533 PolarHBondContact O-N 2.93Å; I531-L533 VanDerWaalsContact C-N 3.29Å; I531-L533 PolarHBondContact O-N 3.22Å; L533-S537 VanDerWaalsContact O-CB 3.25Å; L533-S537 WeakPolarHBondContact O-CB 3.38Å; L533-S537 PolarHBondContact O-N 3.43Å; L533-S537 PolarHBondContact O-OG 2.89Å
534	F	98.3	Very high	96.4	Very high	17 Å²	17	38.3 Å²	38.3	8%	0.075	20%	0.204	C	C	.	.	H	α-helix	trans	-61	-56.1	176.4	-178.9	-102.3	0	0	0	112	I285 P465 A468 A469 V472 S530 I531 S537 M538	I285-F534 HydrophobicContact CB-CD2 4.49Å; I285-F534 HydrophobicContact CD1-CB 3.73Å; I285-F534 HydrophobicContact CD1-CD1 3.92Å; I285-F534 HydrophobicContact CD1-CD2 4.47Å; I285-F534 HydrophobicContact CD1-CG 3.81Å; I285-F534 HydrophobicContact CG1-CB 4.37Å; I285-F534 HydrophobicContact CG1-CD1 4.24Å; I285-F534 HydrophobicContact CG1-CD2 4.24Å; I285-F534 HydrophobicContact CG1-CG 4.04Å; I285-F534 HydrophobicContact CG2-CB 3.87Å; I285-F534 HydrophobicContact CG2-CD2 3.54Å; I285-F534 HydrophobicContact CG2-CE2 4.28Å; I285-F534 HydrophobicContact CG2-CG 3.86Å; P465-F534 HydrophobicContact CB-CB 4.01Å; P465-F534 WeakPolarHBondContact O-CD2 3.41Å; A468-F534 HydrophobicContact CB-CD2 4.14Å; A468-F534 HydrophobicContact CB-CE2 3.96Å; A469-F534 VanDerWaalsContact CA-CE2 3.45Å; A469-F534 HydrophobicContact CB-CD2 3.8Å; A469-F534 HydrophobicContact CB-CE2 3.89Å; A469-F534 HydrophobicContact CB-CG 4.49Å; V472-F534 HydrophobicContact CG2-CZ 4.4Å; S530-F534 VanDerWaalsContact O-CB 3.28Å; S530-F534 WeakPolarHBondContact O-CB 3.35Å; S530-F534 PolarHBondContact O-N 3.05Å; I531-F534 PolarHBondContact O-N 2.99Å; F534-S537 PolarHBondContact O-N 3.48Å; F534-M538 HydrophobicContact CD1-SD 3.91Å; F534-M538 HydrophobicContact CE1-CG 4.27Å; F534-M538 HydrophobicContact CE1-SD 3.26Å; F534-M538 WeakPolarHBondContact CE1-SD 3.11Å; F534-M538 HydrophobicContact CE2-SD 4.47Å; F534-M538 HydrophobicContact CZ-CG 4.41Å; F534-M538 HydrophobicContact CZ-SD 3.59Å; F534-M538 VanDerWaalsContact CZ-SD 3.59Å; F534-M538 WeakPolarHBondContact O-CG 2.88Å; F534-M538 PolarHBondContact O-N 3.22Å
535	F	97.9	Very high	96.7	Very high	115 Å²	115	36.1 Å²	36.1	50%	0.504	19%	0.191	S	C	.	.	H	α-helix	trans	-68.8	-37.6	-178	-74.9	-70.1	0	0	0	111.8	I531 S537 M538 L539	I531-F535 HydrophobicContact CG2-CD2 3.69Å; I531-F535 HydrophobicContact CG2-CE2 3.82Å; I531-F535 VanDerWaalsContact O-CD2 3.29Å; I531-F535 WeakPolarHBondContact O-CD2 3.24Å; I531-F535 PolarHBondContact O-N 3.17Å; F535-S537 VanDerWaalsContact C-N 3.34Å; F535-S537 PolarHBondContact O-N 3.43Å; F535-M538 HydrophobicContact CD1-SD 4.36Å; F535-M538 PolarHBondContact O-N 3.22Å; F535-L539 WeakPolarHBondContact O-CB 3.32Å; F535-L539 VanDerWaalsContact O-CG 3.28Å; F535-L539 WeakPolarHBondContact O-CG 3.44Å; F535-L539 PolarHBondContact O-N 2.94Å
536	G	97.6	Very high	96.9	Very high	22 Å²	22	39.1 Å²	39.1	23%	0.227	21%	0.207	C	C	.	.	H	α-helix	trans	-57.9	-46.1	172.1	0	0	0	0	0	111.9	I532 L539 V540	I532-G536 WeakPolarHBondContact O-CA 3.28Å; I532-G536 PolarHBondContact O-N 3.03Å; G536-L539 PolarHBondContact O-N 2.87Å; G536-V540 WeakPolarHBondContact O-CG2 3.21Å; G536-V540 PolarHBondContact O-N 3.43Å; G536-V540 VanDerWaalsContact O-N 3.15Å
537	S	97.9	Very high	97.1	Very high	1 Å²	1	45.8 Å²	45.8	1%	0.007	24%	0.244	C	C	.	.	H	α-helix	trans	-62.9	-46.2	175.4	-57.7	0	0	0	0	111.3	L533 F534 F535 L539 V540 V541	L533-S537 VanDerWaalsContact O-CB 3.25Å; L533-S537 WeakPolarHBondContact O-CB 3.38Å; L533-S537 PolarHBondContact O-N 3.43Å; L533-S537 PolarHBondContact O-OG 2.89Å; F534-S537 PolarHBondContact O-N 3.48Å; F535-S537 VanDerWaalsContact C-N 3.34Å; F535-S537 PolarHBondContact O-N 3.43Å; S537-L539 VanDerWaalsContact C-N 3.32Å; S537-L539 PolarHBondContact O-N 2.97Å; S537-V540 PolarHBondContact O-N 3.22Å; S537-V541 VanDerWaalsContact O-CG2 3.26Å; S537-V541 WeakPolarHBondContact O-CG2 3.44Å; S537-V541 PolarHBondContact O-N 3.46Å
538	M	98.1	Very high	97.1	Very high	35 Å²	35	47.3 Å²	47.3	17%	0.172	25%	0.253	C	S	.	.	H	α-helix	trans	-58	-42.1	176.9	-74.4	-173.6	74	0	0	112.7	A469 L473 F534 F535 V541 L542	A469-M538 HydrophobicContact CB-CG 3.62Å; L473-M538 HydrophobicContact CD1-CB 4.19Å; L473-M538 HydrophobicContact CD1-CE 4.37Å; L473-M538 HydrophobicContact CD1-CG 4.03Å; L473-M538 HydrophobicContact CD2-CE 3.65Å; L473-M538 HydrophobicContact CG-CE 3.98Å; L473-M538 HydrophobicContact CG-CG 4.41Å; F534-M538 HydrophobicContact CD1-SD 3.91Å; F534-M538 HydrophobicContact CE1-CG 4.27Å; F534-M538 HydrophobicContact CE1-SD 3.26Å; F534-M538 WeakPolarHBondContact CE1-SD 3.11Å; F534-M538 HydrophobicContact CE2-SD 4.47Å; F534-M538 HydrophobicContact CZ-CG 4.41Å; F534-M538 HydrophobicContact CZ-SD 3.59Å; F534-M538 VanDerWaalsContact CZ-SD 3.59Å; F534-M538 WeakPolarHBondContact O-CG 2.88Å; F534-M538 PolarHBondContact O-N 3.22Å; F535-M538 HydrophobicContact CD1-SD 4.36Å; F535-M538 PolarHBondContact O-N 3.22Å; M538-V541 PolarHBondContact O-N 3.29Å; M538-L542 WeakPolarHBondContact O-CB 3.12Å; M538-L542 VanDerWaalsContact O-CG 3.3Å; M538-L542 WeakPolarHBondContact O-CG 3.21Å; M538-L542 PolarHBondContact O-N 3.47Å
539	L	98.1	Very high	96.9	Very high	129 Å²	129	53.6 Å²	53.6	68%	0.675	28%	0.281	S	S	*	.	H	α-helix	trans	-62.6	-43.3	178.7	-74.4	172.9	0	0	0	111.6	F535 G536 S537 G543	F535-L539 WeakPolarHBondContact O-CB 3.32Å; F535-L539 VanDerWaalsContact O-CG 3.28Å; F535-L539 WeakPolarHBondContact O-CG 3.44Å; F535-L539 PolarHBondContact O-N 2.94Å; G536-L539 PolarHBondContact O-N 2.87Å; S537-L539 VanDerWaalsContact C-N 3.32Å; S537-L539 PolarHBondContact O-N 2.97Å; L539-G543 PolarHBondContact O-N 3.24Å
540	V	98.1	Very high	96.8	Very high	41 Å²	41	56.3 Å²	56.3	25%	0.248	30%	0.302	C	S	.	.	H	α-helix	trans	-64.6	-46.6	175.8	176.3	0	0	0	0	110.9	V491 G536 S537 L542 G543 I544	V491-V540 HydrophobicContact CG1-CG2 4.26Å; V491-V540 HydrophobicContact CG2-CG1 4.31Å; G536-V540 WeakPolarHBondContact O-CG2 3.21Å; G536-V540 PolarHBondContact O-N 3.43Å; G536-V540 VanDerWaalsContact O-N 3.15Å; S537-V540 PolarHBondContact O-N 3.22Å; V540-L542 PolarHBondContact O-N 2.97Å; V540-G543 PolarHBondContact O-N 2.93Å; V540-I544 HydrophobicContact CG1-CD1 3.71Å; V540-I544 HydrophobicContact CG1-CG1 4.46Å; V540-I544 WeakPolarHBondContact O-CB 3.25Å; V540-I544 WeakPolarHBondContact O-CG1 3.42Å; V540-I544 PolarHBondContact O-N 2.96Å
541	V	98	Very high	96.5	Very high	0 Å²	0	57.6 Å²	57.6	0%	0	31%	0.308	C	S	.	.	H	α-helix	trans	-57.7	-49.8	178.5	175.2	0	0	0	0	110.8	V470 L473 V480 G484 S537 M538 S545	V470-V541 HydrophobicContact CG2-CG2 3.93Å; L473-V541 HydrophobicContact CD1-CB 3.68Å; L473-V541 HydrophobicContact CD1-CG1 3.51Å; L473-V541 HydrophobicContact CD1-CG2 4.3Å; V480-V541 HydrophobicContact CB-CG1 4.48Å; V480-V541 HydrophobicContact CG1-CG1 3.5Å; V480-V541 HydrophobicContact CG2-CG1 4.09Å; G484-V541 WeakPolarHBondContact O-CA 3.47Å; G484-V541 WeakPolarHBondContact O-CG2 3.4Å; S537-V541 VanDerWaalsContact O-CG2 3.26Å; S537-V541 WeakPolarHBondContact O-CG2 3.44Å; S537-V541 PolarHBondContact O-N 3.46Å; M538-V541 PolarHBondContact O-N 3.29Å; V541-S545 WeakPolarHBondContact O-CB 3.31Å; V541-S545 PolarHBondContact O-N 3.18Å; V541-S545 PolarHBondContact O-OG 3.4Å
542	L	97.8	Very high	96.2	Very high	52 Å²	52	59.7 Å²	59.7	27%	0.272	32%	0.324	S	S	.	.	H	α-helix	trans	-68	-44.9	-178.8	-72	173	0	0	0	111.7	L473 V480 M538 V540 S545 L546	L473-L542 HydrophobicContact CD1-CD2 4.47Å; L473-L542 HydrophobicContact CD1-CG 4.17Å; L473-L542 HydrophobicContact CD2-CD1 4.32Å; L473-L542 HydrophobicContact CD2-CD2 3.89Å; L473-L542 HydrophobicContact CD2-CG 4.16Å; V480-L542 HydrophobicContact CG2-CD2 3.99Å; M538-L542 WeakPolarHBondContact O-CB 3.12Å; M538-L542 VanDerWaalsContact O-CG 3.3Å; M538-L542 WeakPolarHBondContact O-CG 3.21Å; M538-L542 PolarHBondContact O-N 3.47Å; V540-L542 PolarHBondContact O-N 2.97Å; L542-S545 PolarHBondContact O-N 3.35Å; L542-L546 VanDerWaalsContact O-CB 3.3Å; L542-L546 WeakPolarHBondContact O-CB 3.35Å; L542-L546 WeakPolarHBondContact O-CG 3.23Å; L542-L546 PolarHBondContact O-N 3.37Å
543	G	97.4	Very high	95.9	Very high	33 Å²	33	58 Å²	58	34%	0.34	32%	0.316	S	S	.	.	H	α-helix	trans	-57.9	-51.7	179.5	0	0	0	0	0	111.9	L539 V540 L546 L547	L539-G543 PolarHBondContact O-N 3.24Å; V540-G543 PolarHBondContact O-N 2.93Å; G543-L546 PolarHBondContact O-N 2.9Å; G543-L547 VanDerWaalsContact O-CG 3.28Å; G543-L547 WeakPolarHBondContact O-CG 3.16Å; G543-L547 PolarHBondContact O-N 3.41Å
544	I	97.1	Very high	95.5	Very high	48 Å²	48	60.8 Å²	60.8	25%	0.246	33%	0.332	C	S	.	.	H	α-helix	trans	-67.8	-42	179.2	-64.9	173.7	0	0	0	110.9	Q483 W487 V540 L546 L547 T548	Q483-I544 HydrophobicContact CB-CG2 4.24Å; W487-I544 HydrophobicContact CB-CD1 3.37Å; W487-I544 HydrophobicContact CG-CD1 4.03Å; V540-I544 HydrophobicContact CG1-CD1 3.71Å; V540-I544 HydrophobicContact CG1-CG1 4.46Å; V540-I544 WeakPolarHBondContact O-CB 3.25Å; V540-I544 WeakPolarHBondContact O-CG1 3.42Å; V540-I544 PolarHBondContact O-N 2.96Å; I544-L546 VanDerWaalsContact C-N 3.32Å; I544-L546 PolarHBondContact O-N 3.06Å; I544-L547 PolarHBondContact O-N 2.96Å; I544-T548 HydrophobicContact CG2-CG2 4.3Å; I544-T548 WeakPolarHBondContact O-CB 3.36Å; I544-T548 VanDerWaalsContact O-CG2 3.3Å; I544-T548 WeakPolarHBondContact O-CG2 3.3Å; I544-T548 PolarHBondContact O-N 2.67Å; I544-T548 PolarHBondContact O-OG1 3.22Å
545	S	96.8	Very high	95.1	Very high	0 Å²	0	62.3 Å²	62.3	0%	0	34%	0.34	C	S	.	.	H	α-helix	trans	-59.3	-44.6	177.9	-64.5	0	0	0	0	111.3	R479 V480 N481 V541 L542 L547 T548	R479-S545 PolarHBondContact NH1-O 3.19Å; R479-S545 PolarHBondContact NH2-O 3.01Å; V480-S545 WeakPolarHBondContact CA-OG 3.26Å; N481-S545 PolarHBondContact N-OG 3.38Å; V541-S545 WeakPolarHBondContact O-CB 3.31Å; V541-S545 PolarHBondContact O-N 3.18Å; V541-S545 PolarHBondContact O-OG 3.4Å; L542-S545 PolarHBondContact O-N 3.35Å; S545-L547 VanDerWaalsContact C-N 3.27Å; S545-L547 PolarHBondContact O-N 3.3Å; S545-T548 WeakPolarHBondContact CA-OG1 3.19Å; S545-T548 PolarHBondContact O-N 3.31Å; S545-T548 VanDerWaalsContact O-N 3.17Å; S545-T548 VanDerWaalsContact O-O 3.04Å; S545-T548 PolarHBondContact O-OG1 2.89Å; S545-T548 VanDerWaalsContact O-OG1 3.09Å
546	L	96.2	Very high	94.8	Very high	107 Å²	107	56.8 Å²	56.8	56%	0.56	32%	0.316	S	S	*	.	H	α-helix	trans	-64.4	-30.1	-179.5	-74.1	170.2	0	0	0	113.1	R479 L542 G543 I544	R479-L546 HydrophobicContact CG-CD2 3.71Å; R479-L546 VanDerWaalsContact NH2-C 3.32Å; R479-L546 PolarHBondContact NH2-O 3.36Å; L542-L546 VanDerWaalsContact O-CB 3.3Å; L542-L546 WeakPolarHBondContact O-CB 3.35Å; L542-L546 WeakPolarHBondContact O-CG 3.23Å; L542-L546 PolarHBondContact O-N 3.37Å; G543-L546 PolarHBondContact O-N 2.9Å; I544-L546 VanDerWaalsContact C-N 3.32Å; I544-L546 PolarHBondContact O-N 3.06Å
547	L	96.4	Very high	94.4	Very high	156 Å²	156	56.9 Å²	56.9	82%	0.817	31%	0.309	S	S	*	.	H	α-helix	trans	-83.5	-10	177.6	-65.9	172.3	0	0	0	113.9	G543 I544 S545	G543-L547 VanDerWaalsContact O-CG 3.28Å; G543-L547 WeakPolarHBondContact O-CG 3.16Å; G543-L547 PolarHBondContact O-N 3.41Å; I544-L547 PolarHBondContact O-N 2.96Å; S545-L547 VanDerWaalsContact C-N 3.27Å; S545-L547 PolarHBondContact O-N 3.3Å
548	T	93.9	Very high	94.1	Very high	31 Å²	31	59.9 Å²	59.9	19%	0.19	32%	0.32	C	S	.	.	S	Bend	trans	-117.8	165.5	-174.5	51.6	0	0	0	0	110.8	R479 N481 I544 S545	R479-T548 PolarHBondContact NH1-O 3.07Å; R479-T548 PolarHBondContact NH2-O 2.96Å; N481-T548 PolarHBondContact ND2-OG1 3.17Å; N481-T548 PolarHBondContact OD1-OG1 3.33Å; I544-T548 HydrophobicContact CG2-CG2 4.3Å; I544-T548 WeakPolarHBondContact O-CB 3.36Å; I544-T548 VanDerWaalsContact O-CG2 3.3Å; I544-T548 WeakPolarHBondContact O-CG2 3.3Å; I544-T548 PolarHBondContact O-N 2.67Å; I544-T548 PolarHBondContact O-OG1 3.22Å; S545-T548 WeakPolarHBondContact CA-OG1 3.19Å; S545-T548 PolarHBondContact O-N 3.31Å; S545-T548 VanDerWaalsContact O-N 3.17Å; S545-T548 VanDerWaalsContact O-O 3.04Å; S545-T548 PolarHBondContact O-OG1 2.89Å; S545-T548 VanDerWaalsContact O-OG1 3.09Å
549	K	91.5	Very high	93.8	Very high	188 Å²	188	58.2 Å²	58.2	82%	0.817	31%	0.312	S	S	*	.	P	Polyproline II helix	trans	-63.2	137.6	-172	-67.6	-176.2	-179.1	179.4	0	111.6	N481	N481-K549 PolarHBondContact ND2-O 2.93Å
550	P	92.8	Very high	93.5	Very high	83 Å²	83	52.1 Å²	52.1	54%	0.539	28%	0.28	S	S	.	.	P	Polyproline II helix	trans	-72.4	152.9	176	31	-34.7	0	0	0	111.4
551	I	91.5	Very high	93.3	Very high	26 Å²	26	53.8 Å²	53.8	13%	0.133	28%	0.282	C	S	.	.	P	Polyproline II helix	trans	-82	129.1	171.9	-59.1	170.8	0	0	0	108.3	F136 N481 H555 L556 I573	F136-I551 HydrophobicContact CD1-CD1 4.25Å; N481-I551 HydrophobicContact CB-CD1 4.01Å; N481-I551 HydrophobicContact CB-CG1 4.03Å; I551-H555 HydrophobicContact CG2-CB 3.93Å; I551-L556 HydrophobicContact CB-CD1 4.33Å; I551-L556 HydrophobicContact CB-CD2 4.35Å; I551-L556 HydrophobicContact CB-CG 4.5Å; I551-L556 HydrophobicContact CG2-CD1 4.35Å; I551-L556 HydrophobicContact CG2-CD2 3.81Å; I551-L556 HydrophobicContact CG2-CG 3.99Å; I551-I573 HydrophobicContact CG2-CD1 4.11Å
552	P	91.3	Very high	93	Very high	77 Å²	77	58.1 Å²	58.1	50%	0.5	31%	0.309	S	S	.	.	P	Polyproline II helix	trans	-58.6	143.6	174.8	-24	32.2	0	0	0	113.3	V554 H555	P552-V554 PolarHBondContact O-N 2.97Å; P552-V554 VanDerWaalsContact O-N 3.14Å; P552-H555 PolarHBondContact O-N 3.44Å; P552-H555 VanDerWaalsContact O-N 3.12Å
553	D	90.5	Very high	92.7	Very high	57 Å²	57	56.9 Å²	56.9	31%	0.305	30%	0.302	S	S	.	.	G	3₁₀ helix	trans	-61.7	-26.3	-174.6	-76.4	-4.8	0	0	0	113	K478 H555 L556 Y557 L563	K478-D553 IonicContact NZ-OD1 3.46Å; K478-D553 IonicContact NZ-OD2 3Å; K478-D553 PolarHBondContact NZ-OD2 2.87Å; D553-H555 PolarHBondContact O-N 2.94Å; D553-L556 PolarHBondContact O-N 3.41Å; D553-Y557 HydrophobicContact CB-CE1 4.32Å; D553-Y557 WeakPolarHBondContact O-CD1 3.21Å; D553-Y557 WeakPolarHBondContact O-CE1 3.38Å; D553-Y557 PolarHBondContact O-N 3.46Å; D553-L563 HydrophobicContact CB-CD1 4.13Å
554	V	88.9	Confident	92.4	Very high	58 Å²	58	58.9 Å²	58.9	35%	0.352	30%	0.299	S	S	.	.	G	3₁₀ helix	trans	-56.3	-32.3	176.4	-177.9	0	0	0	0	112.6	P552 Y557 I571	P552-V554 PolarHBondContact O-N 2.97Å; P552-V554 VanDerWaalsContact O-N 3.14Å; V554-Y557 HydrophobicContact CB-CE2 4.49Å; V554-I571 HydrophobicContact CG1-CB 4.19Å; V554-I571 HydrophobicContact CG1-CD1 3.89Å; V554-I571 HydrophobicContact CG1-CG1 3.94Å; V554-I571 PolarHBondContact O-N 3.17Å
555	H	89.3	Confident	92	Very high	49 Å²	49	62 Å²	62	23%	0.227	32%	0.316	C	S	.	.	G	3₁₀ helix	trans	-84.5	-11	178.2	-60	-62.9	0	0	0	113.4	I551 P552 D553 L559 I571 I573	I551-H555 HydrophobicContact CG2-CB 3.93Å; P552-H555 PolarHBondContact O-N 3.44Å; P552-H555 VanDerWaalsContact O-N 3.12Å; D553-H555 PolarHBondContact O-N 2.94Å; H555-L559 WeakPolarHBondContact O-CD1 3.45Å; H555-I571 WeakPolarHBondContact CA-O 3.24Å; H555-I571 PolarHBondContact ND1-O 3.34Å; H555-I573 HydrophobicContact CB-CD1 4.1Å; H555-I573 HydrophobicContact CB-CG1 3.65Å
556	L	90.9	Very high	91.5	Very high	0 Å²	0	63.1 Å²	63.1	0%	0	33%	0.325	C	S	.	.	T	Hydrogen-bonded Turn	trans	-108.8	-5.5	-169.5	-59.3	-175.6	0	0	0	113.8	K478 I551 D553 R558 L559 L563	K478-L556 HydrophobicContact CB-CD1 4.34Å; I551-L556 HydrophobicContact CB-CD1 4.33Å; I551-L556 HydrophobicContact CB-CD2 4.35Å; I551-L556 HydrophobicContact CB-CG 4.5Å; I551-L556 HydrophobicContact CG2-CD1 4.35Å; I551-L556 HydrophobicContact CG2-CD2 3.81Å; I551-L556 HydrophobicContact CG2-CG 3.99Å; D553-L556 PolarHBondContact O-N 3.41Å; L556-R558 PolarHBondContact O-N 3.15Å; L556-L559 PolarHBondContact O-N 3.24Å; L556-L563 HydrophobicContact CB-CD1 3.64Å
557	Y	90.9	Very high	91	Very high	23 Å²	23	64.7 Å²	64.7	9%	0.09	34%	0.339	C	S	.	.	T	Hydrogen-bonded Turn	trans	-53.1	133.3	178.6	-63.9	-33.6	0	0	0	111.4	D553 V554 L559 L563 S566 E568 E569 R570	D553-Y557 HydrophobicContact CB-CE1 4.32Å; D553-Y557 WeakPolarHBondContact O-CD1 3.21Å; D553-Y557 WeakPolarHBondContact O-CE1 3.38Å; D553-Y557 PolarHBondContact O-N 3.46Å; V554-Y557 HydrophobicContact CB-CE2 4.49Å; Y557-L559 PolarHBondContact O-N 2.97Å; Y557-L563 HydrophobicContact CD1-CB 4.21Å; Y557-L563 HydrophobicContact CD1-CD1 4.01Å; Y557-L563 HydrophobicContact CD1-CD2 4.17Å; Y557-L563 HydrophobicContact CD1-CG 4.36Å; Y557-L563 HydrophobicContact CE1-CD1 4.32Å; Y557-L563 HydrophobicContact CE1-CD2 4.16Å; Y557-S566 WeakPolarHBondContact CD1-OG 3.35Å; Y557-E568 HydrophobicContact CD2-CB 3.74Å; Y557-E568 HydrophobicContact CE2-CB 3.42Å; Y557-E568 VanDerWaalsContact CE2-CB 3.42Å; Y557-E568 HydrophobicContact CE2-CG 4.3Å; Y557-E568 VanDerWaalsContact CE2-OE2 3.24Å; Y557-E568 WeakPolarHBondContact CE2-OE2 3.14Å; Y557-E568 PolarHBondContact OH-OE2 3.43Å; Y557-E569 WeakPolarHBondContact CD2-O 3.48Å; Y557-R570 WeakPolarHBondContact O-CD 3.45Å
558	R	90.9	Very high	90.6	Very high	64 Å²	64	62.4 Å²	62.4	24%	0.242	32%	0.324	C	S	.	.	T	Hydrogen-bonded Turn	trans	61.2	8.1	-178.4	-60.8	178.2	-71.7	-80.6	1.9	116.1	K122 L556 L563 S566 E568	K122-R558 HydrophobicContact CB-CB 4.19Å; L556-R558 PolarHBondContact O-N 3.15Å; R558-L563 PolarHBondContact N-O 3.34Å; R558-S566 PolarHBondContact NH1-O 2.99Å; R558-E568 PolarHBondContact NH1-O 2.82Å; R558-E568 PolarHBondContact NH2-O 3.44Å
559	L	91.4	Very high	90.2	Very high	0 Å²	0	68.9 Å²	68.9	0%	0	35%	0.352	C	S	.	.	T	Hydrogen-bonded Turn	trans	-105.5	-16.3	179	-65	179.9	0	0	0	114.3	I119 S123 Y131 K134 H555 L556 Y557 R570	I119-L559 WeakPolarHBondContact CG2-O 3.26Å; S123-L559 VanDerWaalsContact CB-CD2 3.43Å; Y131-L559 HydrophobicContact CE2-CD2 4.43Å; Y131-L559 PolarHBondContact OH-O 3.09Å; K134-L559 HydrophobicContact CB-CD1 4.21Å; K134-L559 HydrophobicContact CB-CD2 4.28Å; K134-L559 VanDerWaalsContact O-CD1 3.28Å; K134-L559 WeakPolarHBondContact O-CD1 3.46Å; H555-L559 WeakPolarHBondContact O-CD1 3.45Å; L556-L559 PolarHBondContact O-N 3.24Å; Y557-L559 PolarHBondContact O-N 2.97Å; L559-R570 VanDerWaalsContact CD2-NH1 3.32Å
560	C	92.9	Very high	90	Very high	1 Å²	1	61.5 Å²	61.5	1%	0.007	32%	0.319	C	S	.	.	S	Bend	trans	-132.5	161.6	177.7	71.5	0	0	0	0	111.2	I475 V562 L563 R564	I475-C560 CarbonylContact O-C 3.56Å; I475-C560 WeakPolarHBondContact O-CA 3.34Å; I475-C560 WeakPolarHBondContact O-CB 3.24Å; C560-V562 VanDerWaalsContact C-N 3.32Å; C560-V562 PolarHBondContact O-N 3.23Å; C560-L563 CarbonylContact O-C 3.42Å; C560-L563 PolarHBondContact O-N 3.02Å; C560-R564 WeakPolarHBondContact O-CA 3.45Å; C560-R564 WeakPolarHBondContact O-CB 3.4Å; C560-R564 PolarHBondContact O-N 3.45Å
561	W	92.6	Very high	89.7	Confident	76 Å²	76	61.8 Å²	61.8	29%	0.288	32%	0.315	S	S	.	.	S	Bend	trans	-57.5	-43.3	-174.9	-171.6	-104	0	0	0	112.3	I115 I119 I475 F476 L563 R564	I115-W561 HydrophobicContact CB-CZ3 4.25Å; I115-W561 HydrophobicContact CG1-CH2 4.3Å; I115-W561 HydrophobicContact CG1-CZ3 4.33Å; I115-W561 HydrophobicContact CG2-CE3 4.2Å; I115-W561 HydrophobicContact CG2-CZ3 4.05Å; I119-W561 HydrophobicContact CD1-CB 4.47Å; I119-W561 HydrophobicContact CD1-CE3 4.01Å; I475-W561 HydrophobicContact CG2-CB 4.23Å; I475-W561 WeakPolarHBondContact O-CB 3.48Å; I475-W561 PolarHBondContact O-N 3.13Å; F476-W561 HydrophobicContact CD1-CB 3.95Å; F476-W561 HydrophobicContact CD1-CG 4.05Å; F476-W561 HydrophobicContact CE1-CB 4.25Å; F476-W561 HydrophobicContact CE1-CD2 4.11Å; F476-W561 AromaticContact CE1-CG 3.99Å; F476-W561 HydrophobicContact CE1-CG 3.99Å; W561-L563 VanDerWaalsContact C-N 3.34Å; W561-L563 PolarHBondContact O-N 3.19Å; W561-R564 VanDerWaalsContact O-CD 3.28Å; W561-R564 WeakPolarHBondContact O-CD 3.44Å; W561-R564 WeakPolarHBondContact O-CG 3.39Å; W561-R564 PolarHBondContact O-N 3.48Å; W561-R564 PolarHBondContact O-NH1 3.32Å
562	V	92.3	Very high	89.3	Confident	92 Å²	92	61.3 Å²	61.3	56%	0.558	31%	0.313	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.3	-40.5	-178.1	177.8	0	0	0	0	111.5	C560	C560-V562 VanDerWaalsContact C-N 3.32Å; C560-V562 PolarHBondContact O-N 3.23Å
563	L	90.9	Very high	88.8	Confident	25 Å²	25	60.5 Å²	60.5	13%	0.131	30%	0.304	C	S	.	.	T	Hydrogen-bonded Turn	trans	-101.1	12.7	-175	-60.7	173.6	0	0	0	113.3	D553 L556 Y557 R558 C560 W561 N565 S566	D553-L563 HydrophobicContact CB-CD1 4.13Å; L556-L563 HydrophobicContact CB-CD1 3.64Å; Y557-L563 HydrophobicContact CD1-CB 4.21Å; Y557-L563 HydrophobicContact CD1-CD1 4.01Å; Y557-L563 HydrophobicContact CD1-CD2 4.17Å; Y557-L563 HydrophobicContact CD1-CG 4.36Å; Y557-L563 HydrophobicContact CE1-CD1 4.32Å; Y557-L563 HydrophobicContact CE1-CD2 4.16Å; R558-L563 PolarHBondContact N-O 3.34Å; C560-L563 CarbonylContact O-C 3.42Å; C560-L563 PolarHBondContact O-N 3.02Å; W561-L563 VanDerWaalsContact C-N 3.34Å; W561-L563 PolarHBondContact O-N 3.19Å; L563-N565 PolarHBondContact O-N 2.92Å; L563-N565 VanDerWaalsContact O-N 3.15Å; L563-S566 WeakPolarHBondContact O-CB 3.06Å; L563-S566 PolarHBondContact O-N 3.27Å; L563-S566 VanDerWaalsContact O-N 3.15Å
564	R	90.6	Very high	87.9	Confident	75 Å²	75	58.5 Å²	58.5	28%	0.283	29%	0.293	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63	-24.6	-171.6	73.5	-171.1	-178	-83.8	4.8	114.4	K122 C560 W561	K122-R564 VanDerWaalsContact CD-O 3.31Å; K122-R564 WeakPolarHBondContact CD-O 3.19Å; K122-R564 PolarHBondContact NZ-O 3.27Å; C560-R564 WeakPolarHBondContact O-CA 3.45Å; C560-R564 WeakPolarHBondContact O-CB 3.4Å; C560-R564 PolarHBondContact O-N 3.45Å; W561-R564 VanDerWaalsContact O-CD 3.28Å; W561-R564 WeakPolarHBondContact O-CD 3.44Å; W561-R564 WeakPolarHBondContact O-CG 3.39Å; W561-R564 PolarHBondContact O-N 3.48Å; W561-R564 PolarHBondContact O-NH1 3.32Å
565	N	88.6	Confident	86.7	Confident	113 Å²	113	57.6 Å²	57.6	60%	0.604	29%	0.292	S	S	*	.	T	Hydrogen-bonded Turn	trans	-108.7	9.9	-178.3	-68.7	-18.2	0	0	0	112.8	K122 L563 T567	K122-N565 PolarHBondContact NZ-OD1 3.26Å; L563-N565 PolarHBondContact O-N 2.92Å; L563-N565 VanDerWaalsContact O-N 3.15Å; N565-T567 PolarHBondContact O-N 3Å
566	S	87.6	Confident	85	Confident	25 Å²	25	63 Å²	63	18%	0.175	32%	0.317	C	S	.	.			trans	-61.9	128.7	175.4	-178.7	0	0	0	0	110.3	Y557 R558 L563 E568	Y557-S566 WeakPolarHBondContact CD1-OG 3.35Å; R558-S566 PolarHBondContact NH1-O 2.99Å; L563-S566 WeakPolarHBondContact O-CB 3.06Å; L563-S566 PolarHBondContact O-N 3.27Å; L563-S566 VanDerWaalsContact O-N 3.15Å; S566-E568 VanDerWaalsContact C-N 3.34Å; S566-E568 WeakPolarHBondContact OG-CB 3.31Å; S566-E568 PolarHBondContact OG-N 3.04Å
567	T	85.8	Confident	83.4	Confident	140 Å²	140	66.6 Å²	66.6	86%	0.859	33%	0.334	S	S	*	.			trans	-88.8	-5	173.4	52.7	0	0	0	0	112.4	N565	N565-T567 PolarHBondContact O-N 3Å
568	E	88.1	Confident	81.7	Confident	108 Å²	108	68.9 Å²	68.9	51%	0.505	34%	0.344	S	S	.	.	S	Bend	trans	-67.7	155.1	179.9	-64.6	-177	-151.2	0	0	111.9	Y557 R558 S566 R570	Y557-E568 HydrophobicContact CD2-CB 3.74Å; Y557-E568 HydrophobicContact CE2-CB 3.42Å; Y557-E568 VanDerWaalsContact CE2-CB 3.42Å; Y557-E568 HydrophobicContact CE2-CG 4.3Å; Y557-E568 VanDerWaalsContact CE2-OE2 3.24Å; Y557-E568 WeakPolarHBondContact CE2-OE2 3.14Å; Y557-E568 PolarHBondContact OH-OE2 3.43Å; R558-E568 PolarHBondContact NH1-O 2.82Å; R558-E568 PolarHBondContact NH2-O 3.44Å; S566-E568 VanDerWaalsContact C-N 3.34Å; S566-E568 WeakPolarHBondContact OG-CB 3.31Å; S566-E568 PolarHBondContact OG-N 3.04Å; E568-R570 PolarHBondContact O-N 3.26Å
569	E	85.2	Confident	79.7	Confident	167 Å²	167	68.7 Å²	68.7	78%	0.78	35%	0.353	S	S	*	.	P	Polyproline II helix	trans	-66.6	131.8	176.8	-169.8	172.4	-172.3	0	0	110.1	Y557	Y557-E569 WeakPolarHBondContact CD2-O 3.48Å
570	R	86.9	Confident	77.5	Confident	32 Å²	32	75.4 Å²	75.4	12%	0.121	38%	0.384	C	S	.	.	P	Polyproline II helix	trans	-99.1	122.7	-179.9	-176.2	-175.6	80.9	-173.8	5.1	108.4	Y557 L559 E568 D572	Y557-R570 WeakPolarHBondContact O-CD 3.45Å; L559-R570 VanDerWaalsContact CD2-NH1 3.32Å; E568-R570 PolarHBondContact O-N 3.26Å; R570-D572 IonicContact CZ-OD1 3.52Å; R570-D572 IonicContact NE-OD1 3.63Å; R570-D572 PolarHBondContact NE-OD1 3.49Å; R570-D572 IonicContact NH2-OD1 2.7Å; R570-D572 PolarHBondContact NH2-OD1 3.26Å; R570-D572 IonicContact NH2-OD2 3.34Å; R570-D572 PolarHBondContact NH2-OD2 3.24Å
571	I	85.9	Confident	75.3	Confident	90 Å²	90	79.5 Å²	79.5	46%	0.462	40%	0.403	S	S	.	.			trans	-93.3	108.3	170.4	-55.9	176.8	0	0	0	107.4	V554 H555	V554-I571 HydrophobicContact CG1-CB 4.19Å; V554-I571 HydrophobicContact CG1-CD1 3.89Å; V554-I571 HydrophobicContact CG1-CG1 3.94Å; V554-I571 PolarHBondContact O-N 3.17Å; H555-I571 WeakPolarHBondContact CA-O 3.24Å; H555-I571 PolarHBondContact ND1-O 3.34Å
572	D	83.1	Confident	73.1	Confident	16 Å²	16	83 Å²	83	9%	0.086	42%	0.422	C	S	.	.			trans	-60.2	136.7	175.7	-80.7	2.1	0	0	0	109.6	R570 D574 A575 K578	R570-D572 IonicContact CZ-OD1 3.52Å; R570-D572 IonicContact NE-OD1 3.63Å; R570-D572 PolarHBondContact NE-OD1 3.49Å; R570-D572 IonicContact NH2-OD1 2.7Å; R570-D572 PolarHBondContact NH2-OD1 3.26Å; R570-D572 IonicContact NH2-OD2 3.34Å; R570-D572 PolarHBondContact NH2-OD2 3.24Å; D572-D574 WeakPolarHBondContact CB-OD1 3.49Å; D572-D574 PolarHBondContact O-N 2.93Å; D572-A575 HydrophobicContact CB-CB 4.44Å; D572-A575 WeakPolarHBondContact O-CB 3.41Å; D572-A575 PolarHBondContact O-N 2.75Å; D572-K578 IonicContact OD2-NZ 3.9Å
573	I	82.1	Confident	70.6	Confident	60 Å²	60	84.1 Å²	84.1	31%	0.308	43%	0.43	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.4	-27.8	-179.4	-59.1	173.9	0	0	0	110.7	I551 H555	I551-I573 HydrophobicContact CG2-CD1 4.11Å; H555-I573 HydrophobicContact CB-CD1 4.1Å; H555-I573 HydrophobicContact CB-CG1 3.65Å
574	D	71	Confident	68.1	Low	14 Å²	14	86.5 Å²	86.5	8%	0.075	44%	0.443	C	S	.	.	T	Hydrogen-bonded Turn	trans	-92.5	12	178.1	57.9	-50.8	0	0	0	114.1	D572 E576 E577 K578	D572-D574 WeakPolarHBondContact CB-OD1 3.49Å; D572-D574 PolarHBondContact O-N 2.93Å; D574-E576 VanDerWaalsContact C-N 3.27Å; D574-E576 PolarHBondContact O-N 3.39Å; D574-E577 PolarHBondContact O-N 3.23Å; D574-E577 VanDerWaalsContact O-N 3.11Å; D574-K578 PolarHBondContact O-N 3.43Å; D574-K578 VanDerWaalsContact O-N 3.16Å; D574-K578 WeakPolarHBondContact OD2-CE 3.3Å; D574-K578 IonicContact OD2-NZ 3.87Å; D574-K578 PolarHBondContact OD2-NZ 2.88Å
575	A	64.7	Low	65.8	Low	40 Å²	40	87.9 Å²	87.9	33%	0.331	46%	0.456	S	S	.	.	H	α-helix	trans	-60.6	-32.1	-177.4	0	0	0	0	0	113.9	D572 S579	D572-A575 HydrophobicContact CB-CB 4.44Å; D572-A575 WeakPolarHBondContact O-CB 3.41Å; D572-A575 PolarHBondContact O-N 2.75Å; A575-S579 PolarHBondContact O-N 2.69Å; A575-S579 VanDerWaalsContact O-N 3.11Å; A575-S579 PolarHBondContact O-OG 2.69Å
576	E	53.7	Low	63.3	Low	161 Å²	161	85.8 Å²	85.8	75%	0.752	46%	0.461	S	S	*	.	H	α-helix	trans	-71.8	-32.2	176	-69.2	-177.3	176.1	0	0	112.5	D574 S579 Q580	D574-E576 VanDerWaalsContact C-N 3.27Å; D574-E576 PolarHBondContact O-N 3.39Å; E576-S579 WeakPolarHBondContact CA-OG 2.97Å; E576-S579 PolarHBondContact O-OG 3.08Å; E576-Q580 PolarHBondContact O-N 3.35Å
577	E	57.3	Low	60.9	Low	77 Å²	77	90.4 Å²	90.4	36%	0.36	49%	0.488	S	S	.	.	H	α-helix	trans	-69	-44	174.2	-71.4	178.8	173.2	0	0	110.6	K133 D574 Q580 E581	K133-E577 WeakPolarHBondContact CE-OE2 3.31Å; K133-E577 IonicContact NZ-OE2 3.72Å; K133-E577 PolarHBondContact NZ-OE2 3.39Å; D574-E577 PolarHBondContact O-N 3.23Å; D574-E577 VanDerWaalsContact O-N 3.11Å; E577-Q580 PolarHBondContact O-N 2.88Å; E577-E581 PolarHBondContact O-N 3.4Å
578	K	54.1	Low	58.6	Low	71 Å²	71	90.2 Å²	90.2	31%	0.309	48%	0.477	S	S	.	.	H	α-helix	trans	-66.2	-39.5	179.5	-76.2	177.8	-178.6	148.6	0	113.7	D572 D574 Q580 E581 E582	D572-K578 IonicContact OD2-NZ 3.9Å; D574-K578 PolarHBondContact O-N 3.43Å; D574-K578 VanDerWaalsContact O-N 3.16Å; D574-K578 WeakPolarHBondContact OD2-CE 3.3Å; D574-K578 IonicContact OD2-NZ 3.87Å; D574-K578 PolarHBondContact OD2-NZ 2.88Å; K578-Q580 VanDerWaalsContact C-N 3.29Å; K578-Q580 PolarHBondContact O-N 2.98Å; K578-E581 PolarHBondContact O-N 2.93Å; K578-E582 WeakPolarHBondContact O-CG 3.23Å; K578-E582 PolarHBondContact O-N 3.08Å
579	S	48	Very low	56.1	Low	59 Å²	59	91.5 Å²	91.5	41%	0.413	48%	0.483	S	S	.	.	H	α-helix	trans	-67.8	-29.1	179.6	46.6	0	0	0	0	112.8	A575 E576 T583	A575-S579 PolarHBondContact O-N 2.69Å; A575-S579 VanDerWaalsContact O-N 3.11Å; A575-S579 PolarHBondContact O-OG 2.69Å; E576-S579 WeakPolarHBondContact CA-OG 2.97Å; E576-S579 PolarHBondContact O-OG 3.08Å; S579-T583 PolarHBondContact O-N 3.29Å; S579-T583 PolarHBondContact O-OG1 2.94Å
580	Q	45.2	Very low	53.5	Low	141 Å²	141	90.9 Å²	90.9	66%	0.659	49%	0.485	S	S	*	.	H	α-helix	trans	-73.4	-33.3	171.1	-73.1	-178.1	-3.4	0	0	113	E576 E577 K578 T583 D584	E576-Q580 PolarHBondContact O-N 3.35Å; E577-Q580 PolarHBondContact O-N 2.88Å; K578-Q580 VanDerWaalsContact C-N 3.29Å; K578-Q580 PolarHBondContact O-N 2.98Å; Q580-T583 PolarHBondContact O-OG1 2.97Å; Q580-D584 WeakPolarHBondContact O-CB 3.47Å
581	E	48.2	Very low	51	Low	88 Å²	88	97.5 Å²	97.5	41%	0.411	51%	0.511	S	S	.	.	H	α-helix	trans	-71.7	-44.3	174.6	-71	175.2	169.1	0	0	111.4	E577 K578 T583 D584 D585	E577-E581 PolarHBondContact O-N 3.4Å; K578-E581 PolarHBondContact O-N 2.93Å; E581-T583 PolarHBondContact O-N 2.93Å; E581-D584 PolarHBondContact O-N 3.34Å; E581-D585 PolarHBondContact O-N 3.21Å; E581-D585 VanDerWaalsContact O-N 3.09Å
582	E	45.3	Very low	48.6	Very low	148 Å²	148	99.1 Å²	99.1	69%	0.692	53%	0.527	S	S	*	.	H	α-helix	trans	-67.9	-29.7	179.6	-74.9	-179.7	-173.9	0	0	114.2	K578 D584	K578-E582 WeakPolarHBondContact O-CG 3.23Å; K578-E582 PolarHBondContact O-N 3.08Å; E582-D584 VanDerWaalsContact C-N 3.3Å
583	T	39.6	Very low	46.6	Very low	117 Å²	117	105.3 Å²	105.3	72%	0.718	56%	0.556	S	S	*	*	H	α-helix	trans	-76.1	-19.7	176.2	37.1	0	0	0	0	113.1	S579 Q580 E581	S579-T583 PolarHBondContact O-N 3.29Å; S579-T583 PolarHBondContact O-OG1 2.94Å; Q580-T583 PolarHBondContact O-OG1 2.97Å; E581-T583 PolarHBondContact O-N 2.93Å
584	D	40.1	Very low	44.5	Very low	75 Å²	75	110.8 Å²	110.8	40%	0.401	58%	0.58	S	S	.	*	H	α-helix	trans	-96.8	-23.5	-177.6	-155.3	23.4	0	0	0	111.8	R416 Q580 E581 E582 G586	R416-D584 VanDerWaalsContact CZ-CG 3.49Å; R416-D584 IonicContact CZ-OD1 3.27Å; R416-D584 IonicContact CZ-OD2 3.74Å; R416-D584 IonicContact NE-OD1 2.77Å; R416-D584 IonicContact NE-OD2 3.71Å; R416-D584 PolarHBondContact NE-OD2 3.24Å; R416-D584 IonicContact NH2-OD1 2.79Å; R416-D584 PolarHBondContact NH2-OD1 2.54Å; R416-D584 IonicContact NH2-OD2 2.59Å; R416-D584 PolarHBondContact NH2-OD2 2.62Å; Q580-D584 WeakPolarHBondContact O-CB 3.47Å; E581-D584 PolarHBondContact O-N 3.34Å; E582-D584 VanDerWaalsContact C-N 3.3Å; D584-G586 PolarHBondContact O-N 3.3Å
585	D	41.2	Very low	43.1	Very low	104 Å²	104	116.1 Å²	116.1	56%	0.556	62%	0.619	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.3	-4.4	170	-86.8	-14.2	0	0	0	114	E581 V587	E581-D585 PolarHBondContact O-N 3.21Å; E581-D585 VanDerWaalsContact O-N 3.09Å; D585-V587 PolarHBondContact O-N 3.5Å
586	G	36.8	Very low	42.5	Very low	68 Å²	68	119.9 Å²	119.9	70%	0.701	62%	0.624	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64.6	2.7	174.1	0	0	0	0	0	115.2	D584	D584-G586 PolarHBondContact O-N 3.3Å
587	V	35.8	Very low	42.9	Very low	123 Å²	123	114.5 Å²	114.5	75%	0.745	61%	0.612	S	S	*	*			trans	-125.7	55.6	-178.8	-162.8	0	0	0	0	110.8	D585 E589	D585-V587 PolarHBondContact O-N 3.5Å; V587-E589 PolarHBondContact O-N 3.19Å
588	E	37.5	Very low	43.3	Very low	136 Å²	136	116.4 Å²	116.4	64%	0.636	63%	0.633	S	S	*	*			trans	-77.9	109.2	160	-86.5	-162.5	145	0	0	109.4	D590 K614	E588-D590 PolarHBondContact O-N 3.01Å; E588-K614 IonicContact OE2-NZ 3.26Å
589	E	35.9	Very low	43.8	Very low	135 Å²	135	120.7 Å²	120.7	63%	0.631	66%	0.658	S	S	*	*			trans	-64.9	116.4	168.6	-77.2	-176.1	159.2	0	0	110.5	V587 Y591	V587-E589 PolarHBondContact O-N 3.19Å; E589-Y591 HydrophobicContact CB-CD2 4.18Å; E589-Y591 HydrophobicContact CB-CE2 3.73Å; E589-Y591 WeakPolarHBondContact O-CD2 3.3Å; E589-Y591 PolarHBondContact O-N 2.87Å; E589-Y591 WeakPolarHBondContact OE2-CE2 3.36Å; E589-Y591 PolarHBondContact OE2-OH 3.44Å
590	D	32.3	Very low	44.6	Very low	153 Å²	153	124.5 Å²	124.5	82%	0.818	67%	0.667	S	S	*	*			trans	-76.2	88.9	176	-153.8	17.2	0	0	0	109.5	E588	E588-D590 PolarHBondContact O-N 3.01Å
591	Y	34.2	Very low	45.5	Very low	172 Å²	172	124.4 Å²	124.4	68%	0.675	66%	0.664	S	S	*	*			trans	-72.5	126.4	172.2	-74.6	-89.6	0	0	0	110	E589 E593	E589-Y591 HydrophobicContact CB-CD2 4.18Å; E589-Y591 HydrophobicContact CB-CE2 3.73Å; E589-Y591 WeakPolarHBondContact O-CD2 3.3Å; E589-Y591 PolarHBondContact O-N 2.87Å; E589-Y591 WeakPolarHBondContact OE2-CE2 3.36Å; E589-Y591 PolarHBondContact OE2-OH 3.44Å; Y591-E593 PolarHBondContact O-N 3.46Å
592	P	35.4	Very low	46.3	Very low	123 Å²	123	122.8 Å²	122.8	80%	0.799	67%	0.666	S	S	*	*			trans	-64.9	132.5	-179.2	25.1	-32.1	0	0	0	111.3	Q594	P592-Q594 PolarHBondContact O-N 2.83Å; P592-Q594 VanDerWaalsContact O-N 3.14Å
593	E	40.3	Very low	47.4	Very low	147 Å²	147	122.3 Å²	122.3	69%	0.687	66%	0.659	S	S	*	*			trans	-66.6	110.3	-179.2	-80.6	-162.9	138.1	0	0	111.9	Y591 R596	Y591-E593 PolarHBondContact O-N 3.46Å; E593-R596 IonicContact OE1-CZ 3.5Å; E593-R596 IonicContact OE1-NH1 2.87Å; E593-R596 IonicContact OE1-NH2 2.8Å; E593-R596 PolarHBondContact OE1-NH2 3.29Å
594	Q	37.3	Very low	48.7	Very low	174 Å²	174	117.8 Å²	117.8	81%	0.813	63%	0.63	S	S	*	*	P	Polyproline II helix	trans	-72.4	140.2	165.8	-128.3	173.3	10.1	0	0	110.4	P592 R596	P592-Q594 PolarHBondContact O-N 2.83Å; P592-Q594 VanDerWaalsContact O-N 3.14Å; Q594-R596 WeakPolarHBondContact O-CG 3.45Å; Q594-R596 PolarHBondContact O-N 3.11Å; Q594-R596 VanDerWaalsContact O-N 3.16Å
595	S	42.8	Very low	49.9	Very low	127 Å²	127	117.7 Å²	117.7	89%	0.888	63%	0.63	S	S	*	*	P	Polyproline II helix	trans	-57	118.2	-175.4	68.3	0	0	0	0	111.8
596	R	52.2	Low	50.9	Low	119 Å²	119	117.9 Å²	117.9	45%	0.449	63%	0.626	S	S	.	*	P	Polyproline II helix	trans	-88.9	131.5	-172.6	-61.7	-171	-174.4	151.1	18.2	111.6	E593 Q594 D604	E593-R596 IonicContact OE1-CZ 3.5Å; E593-R596 IonicContact OE1-NH1 2.87Å; E593-R596 IonicContact OE1-NH2 2.8Å; E593-R596 PolarHBondContact OE1-NH2 3.29Å; Q594-R596 WeakPolarHBondContact O-CG 3.45Å; Q594-R596 PolarHBondContact O-N 3.11Å; Q594-R596 VanDerWaalsContact O-N 3.16Å; R596-D604 IonicContact NH1-OD2 3.48Å
597	G	62	Low	52.2	Low	48 Å²	48	115.1 Å²	115.1	50%	0.495	60%	0.595	S	S	.	*	P	Polyproline II helix	trans	-69	155.1	175.8	0	0	0	0	0	114.4	L599 K600 K601	G597-L599 PolarHBondContact O-N 3.43Å; G597-K600 PolarHBondContact O-N 2.99Å; G597-K601 PolarHBondContact O-N 3.13Å; G597-K601 VanDerWaalsContact O-N 3.11Å
598	C	65.3	Low	53.3	Low	117 Å²	117	109.5 Å²	109.5	79%	0.791	56%	0.562	S	S	*	*	H	α-helix	trans	-57.9	-40.8	-172.3	-163.1	0	0	0	0	113.9	K600 K601 A602	C598-K600 PolarHBondContact O-N 3.22Å; C598-K601 PolarHBondContact O-N 3.15Å; C598-A602 WeakPolarHBondContact O-CB 3.49Å; C598-A602 PolarHBondContact O-N 3.43Å
599	L	64.6	Low	54.5	Low	160 Å²	160	103.8 Å²	103.8	84%	0.838	54%	0.536	S	S	*	.	H	α-helix	trans	-63.5	-39.9	178.1	-81.4	159.9	0	0	0	113	G597 A602 Y603	G597-L599 PolarHBondContact O-N 3.43Å; L599-A602 PolarHBondContact O-N 3.3Å; L599-Y603 WeakPolarHBondContact O-CB 3.4Å; L599-Y603 PolarHBondContact O-N 3.45Å
600	K	65.5	Low	55.7	Low	139 Å²	139	101.9 Å²	101.9	60%	0.604	53%	0.527	S	S	*	.	H	α-helix	trans	-73.1	-32.8	178.5	-155	170.6	-174.2	176.1	0	111.2	G597 C598 Y603 D604	G597-K600 PolarHBondContact O-N 2.99Å; C598-K600 PolarHBondContact O-N 3.22Å; K600-Y603 PolarHBondContact O-N 3.42Å; K600-D604 WeakPolarHBondContact O-CB 3.43Å; K600-D604 VanDerWaalsContact O-CG 3.23Å; K600-D604 PolarHBondContact O-N 3.15Å
601	K	63.5	Low	56.7	Low	139 Å²	139	101.7 Å²	101.7	60%	0.604	52%	0.519	S	S	*	.	H	α-helix	trans	-68.8	-37.7	173.1	-154.4	174.1	-173.8	177.2	0	112.1	G597 C598 L605	G597-K601 PolarHBondContact O-N 3.13Å; G597-K601 VanDerWaalsContact O-N 3.11Å; C598-K601 PolarHBondContact O-N 3.15Å; K601-L605 VanDerWaalsContact O-CB 3.23Å; K601-L605 WeakPolarHBondContact O-CB 3.11Å; K601-L605 PolarHBondContact O-N 3.36Å
602	A	64.8	Low	57.8	Low	54 Å²	54	94.4 Å²	94.4	45%	0.446	50%	0.496	S	S	.	.	H	α-helix	trans	-67	-40.2	172	0	0	0	0	0	111.7	C598 L599 L605 F606	C598-A602 WeakPolarHBondContact O-CB 3.49Å; C598-A602 PolarHBondContact O-N 3.43Å; L599-A602 PolarHBondContact O-N 3.3Å; A602-L605 PolarHBondContact O-N 3.26Å; A602-F606 WeakPolarHBondContact O-CB 3.36Å; A602-F606 PolarHBondContact O-N 2.83Å
603	Y	68.1	Low	58.8	Low	139 Å²	139	93.4 Å²	93.4	55%	0.545	49%	0.49	S	S	.	.	H	α-helix	trans	-62.9	-48.7	172.4	178.1	-95.5	0	0	0	112	L599 K600 L605 F606 C607 L609	L599-Y603 WeakPolarHBondContact O-CB 3.4Å; L599-Y603 PolarHBondContact O-N 3.45Å; K600-Y603 PolarHBondContact O-N 3.42Å; Y603-L605 VanDerWaalsContact C-N 3.28Å; Y603-L605 PolarHBondContact O-N 2.83Å; Y603-F606 PolarHBondContact O-N 3.23Å; Y603-C607 WeakPolarHBondContact O-CB 3.36Å; Y603-C607 PolarHBondContact O-N 2.92Å; Y603-L609 HydrophobicContact CE1-CD1 4.36Å
604	D	68.1	Low	59.5	Low	22 Å²	22	94.8 Å²	94.8	12%	0.118	49%	0.493	C	S	.	.	H	α-helix	trans	-62.6	-36.4	177.5	-72.2	-13.2	0	0	0	111.6	R596 K600 C607 G608 L609	R596-D604 IonicContact NH1-OD2 3.48Å; K600-D604 WeakPolarHBondContact O-CB 3.43Å; K600-D604 VanDerWaalsContact O-CG 3.23Å; K600-D604 PolarHBondContact O-N 3.15Å; D604-C607 CarbonylContact O-C 3.58Å; D604-G608 CarbonylContact O-C 3.58Å; D604-G608 WeakPolarHBondContact O-CA 3.36Å; D604-G608 PolarHBondContact O-N 2.92Å; D604-L609 HydrophobicContact CB-CB 4.5Å; D604-L609 PolarHBondContact O-N 2.97Å
605	L	63.7	Low	60.7	Low	73 Å²	73	90.9 Å²	90.9	38%	0.382	48%	0.478	S	S	.	.	H	α-helix	trans	-67.6	-48.8	172.8	-177.5	72.2	0	0	0	110.8	R52 K601 A602 Y603 C607 G608	R52-L605 PolarHBondContact NH2-O 3.49Å; K601-L605 VanDerWaalsContact O-CB 3.23Å; K601-L605 WeakPolarHBondContact O-CB 3.11Å; K601-L605 PolarHBondContact O-N 3.36Å; A602-L605 PolarHBondContact O-N 3.26Å; Y603-L605 VanDerWaalsContact C-N 3.28Å; Y603-L605 PolarHBondContact O-N 2.83Å; L605-C607 VanDerWaalsContact C-N 3.29Å; L605-C607 PolarHBondContact O-N 2.97Å; L605-G608 PolarHBondContact O-N 3.5Å; L605-G608 VanDerWaalsContact O-N 3.12Å
606	F	64	Low	62.2	Low	108 Å²	108	88.6 Å²	88.6	47%	0.474	46%	0.458	S	S	.	.	H	α-helix	trans	-58.5	-44.2	178.7	-175	-104.6	0	0	0	111.1	R52 T194 A602 Y603 G608	R52-F606 PolarHBondContact NH1-O 3.5Å; R52-F606 VanDerWaalsContact NH1-O 3.17Å; T194-F606 HydrophobicContact CG2-CD1 4.07Å; T194-F606 HydrophobicContact CG2-CD2 4.37Å; T194-F606 HydrophobicContact CG2-CE1 3.39Å; T194-F606 HydrophobicContact CG2-CE2 3.74Å; T194-F606 HydrophobicContact CG2-CZ 3.21Å; A602-F606 WeakPolarHBondContact O-CB 3.36Å; A602-F606 PolarHBondContact O-N 2.83Å; Y603-F606 PolarHBondContact O-N 3.23Å; F606-G608 PolarHBondContact O-N 3.39Å
607	C	62.2	Low	63.1	Low	10 Å²	10	91.4 Å²	91.4	7%	0.068	47%	0.474	C	S	.	.	T	Hydrogen-bonded Turn	trans	-84.8	2.7	178.1	-67.3	0	0	0	0	114.2	R427 Y603 D604 L605 L609	R427-C607 PolarHBondContact NH1-O 3.03Å; R427-C607 PolarHBondContact NH2-O 2.84Å; Y603-C607 WeakPolarHBondContact O-CB 3.36Å; Y603-C607 PolarHBondContact O-N 2.92Å; D604-C607 CarbonylContact O-C 3.58Å; L605-C607 VanDerWaalsContact C-N 3.29Å; L605-C607 PolarHBondContact O-N 2.97Å; C607-L609 HydrophobicContact CB-CD1 3.98Å; C607-L609 HydrophobicContact CB-CG 3.99Å; C607-L609 PolarHBondContact O-N 3.4Å; C607-L609 VanDerWaalsContact O-N 3.12Å
608	G	59	Low	63.6	Low	5 Å²	5	96.9 Å²	96.9	5%	0.052	49%	0.487	C	S	.	.	T	Hydrogen-bonded Turn	trans	59	23.1	177.6	0	0	0	0	0	115.9	D604 L605 F606 Q610	D604-G608 CarbonylContact O-C 3.58Å; D604-G608 WeakPolarHBondContact O-CA 3.36Å; D604-G608 PolarHBondContact O-N 2.92Å; L605-G608 PolarHBondContact O-N 3.5Å; L605-G608 VanDerWaalsContact O-N 3.12Å; F606-G608 PolarHBondContact O-N 3.39Å; G608-Q610 PolarHBondContact O-N 2.95Å
609	L	62.5	Low	64	Low	16 Å²	16	96 Å²	96	8%	0.084	47%	0.471	C	S	.	.			trans	-83.7	22.5	-175.5	-65.1	171.8	0	0	0	113.7	K420 I424 Y603 D604 C607	K420-L609 WeakPolarHBondContact CE-O 3.47Å; I424-L609 HydrophobicContact CG1-CD2 4.43Å; Y603-L609 HydrophobicContact CE1-CD1 4.36Å; D604-L609 HydrophobicContact CB-CB 4.5Å; D604-L609 PolarHBondContact O-N 2.97Å; C607-L609 HydrophobicContact CB-CD1 3.98Å; C607-L609 HydrophobicContact CB-CG 3.99Å; C607-L609 PolarHBondContact O-N 3.4Å; C607-L609 VanDerWaalsContact O-N 3.12Å
610	Q	62.7	Low	64.3	Low	94 Å²	94	94.2 Å²	94.2	44%	0.439	46%	0.458	S	S	.	.	P	Polyproline II helix	trans	-72.4	138.8	179.7	-65.8	-172.7	-19.7	0	0	110.1	G53 G608 G612	G53-Q610 WeakPolarHBondContact CA-O 3.43Å; G608-Q610 PolarHBondContact O-N 2.95Å; Q610-G612 PolarHBondContact O-N 2.96Å
611	K	52.6	Low	64.7	Low	149 Å²	149	94.4 Å²	94.4	65%	0.648	46%	0.461	S	S	*	.	P	Polyproline II helix	trans	-70.6	125.8	172.3	-81.2	-173.6	172.1	-174.8	0	108.6
612	G	56.7	Low	65.2	Low	19 Å²	19	90.7 Å²	90.7	20%	0.196	46%	0.456	C	S	.	.	P	Polyproline II helix	trans	-67.2	163	169.1	0	0	0	0	0	112.1	Q610 K614	Q610-G612 PolarHBondContact O-N 2.96Å; G612-K614 PolarHBondContact O-N 3.47Å
613	P	57.3	Low	65.5	Low	102 Å²	102	91.5 Å²	91.5	66%	0.662	45%	0.453	S	S	*	.	P	Polyproline II helix	trans	-63.3	133.1	172.5	26	-31.5	0	0	0	110.4	L615	P613-L615 PolarHBondContact O-N 3.25Å
614	K	54.5	Low	65.6	Low	176 Å²	176	92 Å²	92	77%	0.765	45%	0.454	S	S	*	.	P	Polyproline II helix	trans	-69.6	120	171.7	-74.8	-170.4	172.8	-168.8	0	108.5	E588 G612	E588-K614 IonicContact OE2-NZ 3.26Å; G612-K614 PolarHBondContact O-N 3.47Å
615	L	62.5	Low	66	Low	92 Å²	92	98.7 Å²	98.7	48%	0.482	48%	0.482	S	S	.	.	P	Polyproline II helix	trans	-81.1	147.8	175.5	-72.4	147.1	0	0	0	109.8	P613 E619 L623	P613-L615 PolarHBondContact O-N 3.25Å; L615-E619 HydrophobicContact CB-CB 4.24Å; L615-E619 HydrophobicContact CD2-CB 3.71Å; L615-L623 HydrophobicContact CD1-CD2 3.97Å
616	T	74.1	Confident	66.6	Low	79 Å²	79	103.1 Å²	103.1	49%	0.485	50%	0.498	S	S	.	.	P	Polyproline II helix	trans	-72.8	158.4	167.5	57.7	0	0	0	0	110.7	E618 E619 E620	T616-E618 PolarHBondContact O-N 3.44Å; T616-E619 PolarHBondContact N-OE2 3.45Å; T616-E619 PolarHBondContact O-N 3.49Å; T616-E619 WeakPolarHBondContact OG1-CB 3.36Å; T616-E619 WeakPolarHBondContact OG1-CG 3.43Å; T616-E619 PolarHBondContact OG1-N 3.2Å; T616-E619 PolarHBondContact OG1-OE2 2.73Å; T616-E620 PolarHBondContact O-N 2.74Å
617	K	71.5	Confident	67	Low	178 Å²	178	100.7 Å²	100.7	77%	0.774	49%	0.49	S	S	*	.	H	α-helix	trans	-55.9	-38.6	179	-70.7	-169.7	175	-169.4	0	112.9	E620 E621	K617-E620 PolarHBondContact O-N 2.91Å; K617-E621 WeakPolarHBondContact O-CG 3.3Å; K617-E621 PolarHBondContact O-N 2.84Å
618	E	72.4	Confident	67.9	Low	164 Å²	164	102.3 Å²	102.3	77%	0.766	50%	0.499	S	S	*	.	H	α-helix	trans	-66.4	-40.9	176.2	-67.3	-175	174.7	0	0	112.2	T616 E620 A622	T616-E618 PolarHBondContact O-N 3.44Å; E618-E620 VanDerWaalsContact C-N 3.33Å; E618-A622 VanDerWaalsContact O-CB 3.26Å; E618-A622 WeakPolarHBondContact O-CB 3.41Å; E618-A622 PolarHBondContact O-N 2.65Å
619	E	74.5	Confident	69	Low	99 Å²	99	106.1 Å²	106.1	46%	0.463	52%	0.518	S	S	.	.	H	α-helix	trans	-67.2	-35.5	175.3	-71.7	169.7	145	0	0	111.8	L615 T616 L623	L615-E619 HydrophobicContact CB-CB 4.24Å; L615-E619 HydrophobicContact CD2-CB 3.71Å; T616-E619 PolarHBondContact N-OE2 3.45Å; T616-E619 PolarHBondContact O-N 3.49Å; T616-E619 WeakPolarHBondContact OG1-CB 3.36Å; T616-E619 WeakPolarHBondContact OG1-CG 3.43Å; T616-E619 PolarHBondContact OG1-N 3.2Å; T616-E619 PolarHBondContact OG1-OE2 2.73Å; E619-L623 WeakPolarHBondContact O-CB 3.43Å; E619-L623 PolarHBondContact O-N 3.06Å
620	E	69.3	Low	70.1	Confident	122 Å²	122	106.8 Å²	106.8	57%	0.57	52%	0.523	S	S	*	.	H	α-helix	trans	-68.5	-42.8	176.9	-169.5	172.2	-164.4	0	0	112	T616 K617 E618 L623 R624	T616-E620 PolarHBondContact O-N 2.74Å; K617-E620 PolarHBondContact O-N 2.91Å; E618-E620 VanDerWaalsContact C-N 3.33Å; E620-L623 PolarHBondContact O-N 2.92Å; E620-R624 VanDerWaalsContact O-CB 3.32Å; E620-R624 WeakPolarHBondContact O-CB 3.47Å; E620-R624 PolarHBondContact O-N 2.71Å
621	E	74	Confident	71.3	Confident	142 Å²	142	105.9 Å²	105.9	66%	0.664	53%	0.528	S	S	*	.	H	α-helix	trans	-65.3	-43.1	172.9	-76.5	-177.6	-174.5	0	0	112.2	K617 L623 R624 K625	K617-E621 WeakPolarHBondContact O-CG 3.3Å; K617-E621 PolarHBondContact O-N 2.84Å; E621-L623 VanDerWaalsContact C-N 3.32Å; E621-L623 PolarHBondContact O-N 2.98Å; E621-R624 PolarHBondContact O-N 3.04Å; E621-K625 WeakPolarHBondContact O-CB 3.48Å; E621-K625 PolarHBondContact O-N 3.37Å
622	A	74.1	Confident	73	Confident	61 Å²	61	101 Å²	101	50%	0.504	51%	0.507	S	S	.	.	H	α-helix	trans	-62.8	-40.9	175.9	0	0	0	0	0	111.5	E618 K626	E618-A622 VanDerWaalsContact O-CB 3.26Å; E618-A622 WeakPolarHBondContact O-CB 3.41Å; E618-A622 PolarHBondContact O-N 2.65Å; A622-K626 WeakPolarHBondContact O-CB 3.39Å; A622-K626 PolarHBondContact O-N 3.35Å
623	L	71.3	Confident	74.7	Confident	71 Å²	71	109 Å²	109	37%	0.372	53%	0.531	S	S	.	.	H	α-helix	trans	-63.5	-49.5	173.6	-175.4	64.8	0	0	0	110.2	L615 E619 E620 E621 K625 K626 L627	L615-L623 HydrophobicContact CD1-CD2 3.97Å; E619-L623 WeakPolarHBondContact O-CB 3.43Å; E619-L623 PolarHBondContact O-N 3.06Å; E620-L623 PolarHBondContact O-N 2.92Å; E621-L623 VanDerWaalsContact C-N 3.32Å; E621-L623 PolarHBondContact O-N 2.98Å; L623-K625 VanDerWaalsContact C-N 3.31Å; L623-K625 PolarHBondContact O-N 3.2Å; L623-K626 CarbonylContact O-C 3.44Å; L623-K626 WeakPolarHBondContact O-CB 3.46Å; L623-K626 PolarHBondContact O-N 2.88Å; L623-K626 VanDerWaalsContact O-N 3.1Å; L623-L627 HydrophobicContact CD1-CD1 4.44Å; L623-L627 HydrophobicContact CD1-CG 4.34Å; L623-L627 HydrophobicContact CG-CD1 3.91Å; L623-L627 HydrophobicContact CG-CG 4.24Å; L623-L627 WeakPolarHBondContact O-CB 3.43Å; L623-L627 WeakPolarHBondContact O-CG 3.35Å; L623-L627 PolarHBondContact O-N 3.39Å
624	R	71.9	Confident	76.5	Confident	151 Å²	151	109.4 Å²	109.4	57%	0.57	53%	0.534	S	S	*	.	H	α-helix	trans	-57	-44.2	177.9	-170.8	175.6	-179.2	-175.2	-0.1	111.7	E620 E621 K626 L627 T628	E620-R624 VanDerWaalsContact O-CB 3.32Å; E620-R624 WeakPolarHBondContact O-CB 3.47Å; E620-R624 PolarHBondContact O-N 2.71Å; E621-R624 PolarHBondContact O-N 3.04Å; R624-K626 PolarHBondContact O-N 3.46Å; R624-L627 PolarHBondContact O-N 3.04Å; R624-T628 WeakPolarHBondContact O-CG2 3.5Å; R624-T628 PolarHBondContact O-N 2.64Å; R624-T628 PolarHBondContact O-OG1 3.33Å; R624-T628 VanDerWaalsContact O-OG1 3.06Å
625	K	76.3	Confident	78.4	Confident	162 Å²	162	106.8 Å²	106.8	70%	0.704	53%	0.528	S	S	*	.	H	α-helix	trans	-60.4	-46.2	175.6	-170.9	175	-177.4	176.1	0	111.5	E621 L623 L627 T628 D629	E621-K625 WeakPolarHBondContact O-CB 3.48Å; E621-K625 PolarHBondContact O-N 3.37Å; L623-K625 VanDerWaalsContact C-N 3.31Å; L623-K625 PolarHBondContact O-N 3.2Å; K625-L627 VanDerWaalsContact C-N 3.34Å; K625-L627 PolarHBondContact O-N 3.03Å; K625-T628 PolarHBondContact O-N 3.29Å; K625-T628 PolarHBondContact O-OG1 2.92Å; K625-T628 VanDerWaalsContact O-OG1 3.13Å; K625-D629 PolarHBondContact O-N 2.98Å; K625-D629 VanDerWaalsContact O-N 3.17Å
626	K	75.8	Confident	79.9	Confident	165 Å²	165	108.8 Å²	108.8	72%	0.717	53%	0.529	S	S	*	.	H	α-helix	trans	-61.4	-40.8	175.3	-176.2	-176.9	176.5	-172.7	0	112	A622 L623 R624 D629	A622-K626 WeakPolarHBondContact O-CB 3.39Å; A622-K626 PolarHBondContact O-N 3.35Å; L623-K626 CarbonylContact O-C 3.44Å; L623-K626 WeakPolarHBondContact O-CB 3.46Å; L623-K626 PolarHBondContact O-N 2.88Å; L623-K626 VanDerWaalsContact O-N 3.1Å; R624-K626 PolarHBondContact O-N 3.46Å; K626-D629 PolarHBondContact O-N 3.34Å
627	L	72.3	Confident	80.9	Confident	58 Å²	58	111.7 Å²	111.7	30%	0.304	53%	0.531	S	S	.	.	H	α-helix	trans	-67.9	-34.5	178.2	-64.7	172	0	0	0	111.4	R63 I121 L623 R624 K625 D629	R63-L627 HydrophobicContact CB-CD2 4.32Å; R63-L627 HydrophobicContact CG-CD2 4.14Å; R63-L627 VanDerWaalsContact CZ-O 3.26Å; R63-L627 PolarHBondContact NH1-O 2.9Å; R63-L627 PolarHBondContact NH2-O 2.94Å; I121-L627 WeakPolarHBondContact CG2-O 3.21Å; L623-L627 HydrophobicContact CD1-CD1 4.44Å; L623-L627 HydrophobicContact CD1-CG 4.34Å; L623-L627 HydrophobicContact CG-CD1 3.91Å; L623-L627 HydrophobicContact CG-CG 4.24Å; L623-L627 WeakPolarHBondContact O-CB 3.43Å; L623-L627 WeakPolarHBondContact O-CG 3.35Å; L623-L627 PolarHBondContact O-N 3.39Å; R624-L627 PolarHBondContact O-N 3.04Å; K625-L627 VanDerWaalsContact C-N 3.34Å; K625-L627 PolarHBondContact O-N 3.03Å; L627-D629 VanDerWaalsContact C-N 3.35Å
628	T	79.9	Confident	82.1	Confident	43 Å²	43	105.4 Å²	105.4	26%	0.264	51%	0.512	S	S	.	.	H	α-helix	trans	-87.1	-1.8	179.4	56.3	0	0	0	0	114.5	R624 K625	R624-T628 WeakPolarHBondContact O-CG2 3.5Å; R624-T628 PolarHBondContact O-N 2.64Å; R624-T628 PolarHBondContact O-OG1 3.33Å; R624-T628 VanDerWaalsContact O-OG1 3.06Å; K625-T628 PolarHBondContact O-N 3.29Å; K625-T628 PolarHBondContact O-OG1 2.92Å; K625-T628 VanDerWaalsContact O-OG1 3.13Å
629	D	83.3	Confident	83.3	Confident	85 Å²	85	100.8 Å²	100.8	46%	0.455	49%	0.492	S	S	.	.			trans	-71.8	134	-178.7	-172.3	22.4	0	0	0	111.6	K625 K626 L627 S631	K625-D629 PolarHBondContact O-N 2.98Å; K625-D629 VanDerWaalsContact O-N 3.17Å; K626-D629 PolarHBondContact O-N 3.34Å; L627-D629 VanDerWaalsContact C-N 3.35Å; D629-S631 VanDerWaalsContact OD1-CB 3.23Å; D629-S631 WeakPolarHBondContact OD1-CB 3.43Å; D629-S631 PolarHBondContact OD1-N 3.41Å; D629-S631 PolarHBondContact OD1-OG 2.89Å; D629-S631 PolarHBondContact OD2-OG 3.23Å
630	T	86.2	Confident	84.3	Confident	30 Å²	30	96.4 Å²	96.4	18%	0.184	47%	0.472	C	S	.	.			trans	-123.2	15.3	174.9	66	0	0	0	0	111.8	I121 K122	I121-T630 HydrophobicContact CB-CG2 4.08Å; I121-T630 HydrophobicContact CG2-CG2 3.68Å; K122-T630 HydrophobicContact CD-CG2 4.3Å; K122-T630 WeakPolarHBondContact CE-OG1 3.33Å; K122-T630 HydrophobicContact CG-CG2 3.65Å
631	S	86.3	Confident	85.7	Confident	76 Å²	76	93 Å²	93	53%	0.531	46%	0.457	S	S	.	.			trans	-63.1	147.4	177	76.1	0	0	0	0	110.8	D629	D629-S631 VanDerWaalsContact OD1-CB 3.23Å; D629-S631 WeakPolarHBondContact OD1-CB 3.43Å; D629-S631 PolarHBondContact OD1-N 3.41Å; D629-S631 PolarHBondContact OD1-OG 2.89Å; D629-S631 PolarHBondContact OD2-OG 3.23Å
632	E	89.9	Confident	86.8	Confident	47 Å²	47	91.6 Å²	91.6	22%	0.22	45%	0.453	C	S	.	.			trans	-131	144.4	-179	-69.3	-175.7	102.1	0	0	110.6	M307 S308 K311 R637	M307-E632 HydrophobicContact CB-CG 3.71Å; M307-E632 HydrophobicContact CG-CG 4.08Å; S308-E632 WeakPolarHBondContact CA-OE1 3.41Å; S308-E632 PolarHBondContact N-OE1 2.79Å; S308-E632 WeakPolarHBondContact OG-CG 3.2Å; S308-E632 PolarHBondContact OG-OE1 3.36Å; K311-E632 WeakPolarHBondContact CD-OE1 3.37Å; K311-E632 VanDerWaalsContact NZ-CD 3.3Å; K311-E632 IonicContact NZ-OE1 3.58Å; K311-E632 PolarHBondContact NZ-OE1 3.45Å; K311-E632 IonicContact NZ-OE2 2.72Å; K311-E632 PolarHBondContact NZ-OE2 2.95Å; E632-R637 HydrophobicContact CB-CB 4.17Å
633	R	91.9	Very high	87.9	Confident	187 Å²	187	91.6 Å²	91.6	71%	0.706	45%	0.445	S	S	*	.			trans	-70.6	133	170.2	-64.2	-175.9	-177.9	-169.1	1.3	109.4	L635 W636 R637	R633-L635 VanDerWaalsContact C-N 3.31Å; R633-L635 PolarHBondContact O-N 3.39Å; R633-W636 PolarHBondContact O-N 2.81Å; R633-R637 PolarHBondContact O-N 2.91Å
634	P	93.8	Very high	89.1	Confident	110 Å²	110	88.7 Å²	88.7	71%	0.714	43%	0.431	S	S	*	.	H	α-helix	trans	-54.5	-41.5	-174	-28.9	34.6	0	0	0	114.6	A638	P634-A638 PolarHBondContact O-N 3.26Å
635	L	95.4	Very high	90.3	Very high	121 Å²	121	87.2 Å²	87.2	63%	0.634	43%	0.433	S	S	*	.	H	α-helix	trans	-60.4	-52.1	178.7	-179.9	68	0	0	0	111.8	R633 R637 A638 I639	R633-L635 VanDerWaalsContact C-N 3.31Å; R633-L635 PolarHBondContact O-N 3.39Å; L635-R637 PolarHBondContact O-N 3.4Å; L635-A638 WeakPolarHBondContact O-CB 3.42Å; L635-A638 PolarHBondContact O-N 3.31Å; L635-I639 HydrophobicContact CD1-CD1 4.37Å; L635-I639 HydrophobicContact CG-CD1 4.08Å; L635-I639 WeakPolarHBondContact O-CG1 3.01Å; L635-I639 PolarHBondContact O-N 2.89Å
636	W	94.3	Very high	91.4	Very high	134 Å²	134	84.1 Å²	84.1	51%	0.508	42%	0.424	S	S	.	.	H	α-helix	trans	-67.7	-37	-177.7	-70.3	117.5	0	0	0	112.1	R633 A638 I639 V640	R633-W636 PolarHBondContact O-N 2.81Å; W636-A638 VanDerWaalsContact C-N 3.32Å; W636-A638 PolarHBondContact O-N 2.97Å; W636-I639 HydrophobicContact CD2-CD1 4.38Å; W636-I639 HydrophobicContact CE3-CB 4.45Å; W636-I639 HydrophobicContact CE3-CD1 3.67Å; W636-I639 HydrophobicContact CZ3-CD1 3.78Å; W636-I639 PolarHBondContact O-N 3.39Å; W636-V640 WeakPolarHBondContact O-CG2 3.15Å; W636-V640 PolarHBondContact O-N 3.36Å
637	R	95.1	Very high	92.4	Very high	140 Å²	140	76.3 Å²	76.3	53%	0.528	39%	0.39	S	S	.	.	H	α-helix	trans	-57.3	-43.5	171.3	179.8	178.6	163.5	-165.3	-4.6	112	E632 R633 L635 V640 N641	E632-R637 HydrophobicContact CB-CB 4.17Å; R633-R637 PolarHBondContact O-N 2.91Å; L635-R637 PolarHBondContact O-N 3.4Å; R637-V640 VanDerWaalsContact O-CG2 3.31Å; R637-V640 WeakPolarHBondContact O-CG2 3.31Å; R637-N641 WeakPolarHBondContact O-CB 3.3Å; R637-N641 PolarHBondContact O-N 3.33Å; R637-N641 VanDerWaalsContact O-N 3.12Å; R637-N641 PolarHBondContact O-ND2 3.01Å
638	A	96.6	Very high	93.5	Very high	46 Å²	46	76.8 Å²	76.8	38%	0.38	39%	0.393	S	S	.	.	H	α-helix	trans	-65.2	-45.2	177.3	0	0	0	0	0	111.7	P634 L635 W636 V640 N641 I642	P634-A638 PolarHBondContact O-N 3.26Å; L635-A638 WeakPolarHBondContact O-CB 3.42Å; L635-A638 PolarHBondContact O-N 3.31Å; W636-A638 VanDerWaalsContact C-N 3.32Å; W636-A638 PolarHBondContact O-N 2.97Å; A638-V640 PolarHBondContact O-N 3.45Å; A638-N641 PolarHBondContact O-N 3.43Å; A638-I642 WeakPolarHBondContact O-CG1 3.26Å; A638-I642 PolarHBondContact O-N 3.49Å
639	I	96.9	Very high	94.4	Very high	66 Å²	66	77.6 Å²	77.6	34%	0.338	40%	0.404	S	S	.	.	H	α-helix	trans	-58.4	-49.1	178.9	-68.7	167.3	0	0	0	111.3	L635 W636 N641 I642 N643	L635-I639 HydrophobicContact CD1-CD1 4.37Å; L635-I639 HydrophobicContact CG-CD1 4.08Å; L635-I639 WeakPolarHBondContact O-CG1 3.01Å; L635-I639 PolarHBondContact O-N 2.89Å; W636-I639 HydrophobicContact CD2-CD1 4.38Å; W636-I639 HydrophobicContact CE3-CB 4.45Å; W636-I639 HydrophobicContact CE3-CD1 3.67Å; W636-I639 HydrophobicContact CZ3-CD1 3.78Å; W636-I639 PolarHBondContact O-N 3.39Å; I639-N641 PolarHBondContact O-N 3.03Å; I639-I642 PolarHBondContact O-N 3.23Å; I639-N643 PolarHBondContact O-N 3.43Å; I639-N643 VanDerWaalsContact O-N 3.08Å; I639-N643 PolarHBondContact O-ND2 3.5Å
640	V	96.8	Very high	95	Very high	7 Å²	7	76.2 Å²	76.2	4%	0.042	40%	0.398	C	S	.	.	H	α-helix	trans	-67	-37.2	-179.8	-61.1	0	0	0	0	111.7	W114 K311 A312 I315 W636 R637 A638 N643 A644	W114-V640 HydrophobicContact CH2-CB 4.21Å; W114-V640 HydrophobicContact CH2-CG2 4.39Å; W114-V640 HydrophobicContact CZ2-CB 4.2Å; W114-V640 HydrophobicContact CZ2-CG2 3.97Å; K311-V640 HydrophobicContact CB-CB 4.23Å; K311-V640 HydrophobicContact CB-CG1 4.38Å; K311-V640 HydrophobicContact CB-CG2 4.17Å; K311-V640 HydrophobicContact CD-CG2 3.96Å; A312-V640 HydrophobicContact CB-CG1 4.07Å; I315-V640 HydrophobicContact CD1-CB 4.11Å; I315-V640 WeakPolarHBondContact CD1-O 3.33Å; W636-V640 WeakPolarHBondContact O-CG2 3.15Å; W636-V640 PolarHBondContact O-N 3.36Å; R637-V640 VanDerWaalsContact O-CG2 3.31Å; R637-V640 WeakPolarHBondContact O-CG2 3.31Å; A638-V640 PolarHBondContact O-N 3.45Å; V640-N643 PolarHBondContact O-N 2.98Å; V640-A644 WeakPolarHBondContact O-CB 3.39Å; V640-A644 PolarHBondContact O-N 3.37Å
641	N	97.1	Very high	95.4	Very high	50 Å²	50	75 Å²	75	27%	0.267	39%	0.391	S	S	.	.	H	α-helix	trans	-65.2	-43.1	176.9	-71.9	-18.7	0	0	0	112.3	W114 R637 A638 I639 N643 A644 I645	W114-N641 WeakPolarHBondContact CZ2-OD1 3.17Å; W114-N641 PolarHBondContact NE1-OD1 3.01Å; R637-N641 WeakPolarHBondContact O-CB 3.3Å; R637-N641 PolarHBondContact O-N 3.33Å; R637-N641 VanDerWaalsContact O-N 3.12Å; R637-N641 PolarHBondContact O-ND2 3.01Å; A638-N641 PolarHBondContact O-N 3.43Å; I639-N641 PolarHBondContact O-N 3.03Å; N641-N643 VanDerWaalsContact C-N 3.33Å; N641-N643 PolarHBondContact O-N 2.9Å; N641-A644 PolarHBondContact O-N 2.95Å; N641-I645 WeakPolarHBondContact O-CG1 3.09Å; N641-I645 PolarHBondContact O-N 3.49Å; N641-I645 VanDerWaalsContact O-N 3.1Å
642	I	97.6	Very high	95.8	Very high	113 Å²	113	76.5 Å²	76.5	58%	0.579	40%	0.397	S	S	*	.	H	α-helix	trans	-60.9	-45.5	176.6	-69.7	165.7	0	0	0	110.2	A638 I639 A644 I645 L646	A638-I642 WeakPolarHBondContact O-CG1 3.26Å; A638-I642 PolarHBondContact O-N 3.49Å; I639-I642 PolarHBondContact O-N 3.23Å; I642-A644 VanDerWaalsContact C-N 3.34Å; I642-A644 PolarHBondContact O-N 3.49Å; I642-I645 PolarHBondContact O-N 3.2Å; I642-L646 PolarHBondContact O-N 3.19Å
643	N	97.4	Very high	96.1	Very high	61 Å²	61	81 Å²	81	33%	0.326	42%	0.416	S	S	.	.	H	α-helix	trans	-65.9	-35.1	178.7	-82.3	-85.5	0	0	0	112.8	I315 Y319 I639 V640 N641 I645 L646 L647	I315-N643 HydrophobicContact CD1-CB 3.93Å; I315-N643 HydrophobicContact CG2-CB 4.18Å; Y319-N643 PolarHBondContact OH-O 3.04Å; I639-N643 PolarHBondContact O-N 3.43Å; I639-N643 VanDerWaalsContact O-N 3.08Å; I639-N643 PolarHBondContact O-ND2 3.5Å; V640-N643 PolarHBondContact O-N 2.98Å; N641-N643 VanDerWaalsContact C-N 3.33Å; N641-N643 PolarHBondContact O-N 2.9Å; N643-I645 VanDerWaalsContact C-N 3.34Å; N643-L646 PolarHBondContact O-N 3Å; N643-L647 VanDerWaalsContact O-CB 3.3Å; N643-L647 WeakPolarHBondContact O-CB 3.34Å; N643-L647 PolarHBondContact O-N 3.46Å
644	A	96.9	Very high	96.2	Very high	10 Å²	10	73.3 Å²	73.3	8%	0.083	39%	0.388	C	S	.	.	H	α-helix	trans	-63	-41.3	173.6	0	0	0	0	0	111.7	W114 I315 V640 N641 I642 L647 L648	W114-A644 HydrophobicContact CH2-CB 3.94Å; W114-A644 HydrophobicContact CZ2-CB 4.02Å; I315-A644 HydrophobicContact CD1-CB 4.12Å; I315-A644 HydrophobicContact CG1-CB 4.49Å; V640-A644 WeakPolarHBondContact O-CB 3.39Å; V640-A644 PolarHBondContact O-N 3.37Å; N641-A644 PolarHBondContact O-N 2.95Å; I642-A644 VanDerWaalsContact C-N 3.34Å; I642-A644 PolarHBondContact O-N 3.49Å; A644-L647 PolarHBondContact O-N 2.95Å; A644-L648 VanDerWaalsContact O-CG 3.32Å; A644-L648 WeakPolarHBondContact O-CG 3.22Å; A644-L648 PolarHBondContact O-N 3.47Å
645	I	97.3	Very high	96.2	Very high	120 Å²	120	69.5 Å²	69.5	62%	0.615	36%	0.36	S	S	*	.	H	α-helix	trans	-65.9	-44.7	176.5	-65.1	167.2	0	0	0	110.6	N641 I642 N643 L647 L648 A649	N641-I645 WeakPolarHBondContact O-CG1 3.09Å; N641-I645 PolarHBondContact O-N 3.49Å; N641-I645 VanDerWaalsContact O-N 3.1Å; I642-I645 PolarHBondContact O-N 3.2Å; N643-I645 VanDerWaalsContact C-N 3.34Å; I645-L647 VanDerWaalsContact C-N 3.35Å; I645-L647 PolarHBondContact O-N 3.33Å; I645-L648 PolarHBondContact O-N 3.36Å; I645-A649 WeakPolarHBondContact O-CB 3.31Å; I645-A649 PolarHBondContact O-N 3.05Å
646	L	97.8	Very high	96.2	Very high	98 Å²	98	66.4 Å²	66.4	51%	0.513	36%	0.357	S	S	.	.	H	α-helix	trans	-57.6	-48.8	176.6	-168.4	94.2	0	0	0	111	Y319 I642 N643 L648 A649 V650	Y319-L646 VanDerWaalsContact OH-CD2 3.3Å; Y319-L646 WeakPolarHBondContact OH-CD2 3.23Å; I642-L646 PolarHBondContact O-N 3.19Å; N643-L646 PolarHBondContact O-N 3Å; L646-L648 PolarHBondContact O-N 3Å; L646-A649 PolarHBondContact O-N 3.22Å; L646-V650 WeakPolarHBondContact O-CG2 3.46Å; L646-V650 PolarHBondContact O-N 3.09Å
647	L	97.3	Very high	96.2	Very high	0 Å²	0	67.1 Å²	67.1	0%	0	36%	0.361	C	S	.	.	H	α-helix	trans	-56.1	-49.7	177	171.8	71.8	0	0	0	111.4	P110 A318 Y319 N643 A644 I645 A649 V650 V651	P110-L647 HydrophobicContact CG-CD2 3.79Å; A318-L647 HydrophobicContact CB-CD1 4.01Å; A318-L647 HydrophobicContact CB-CD2 3.38Å; A318-L647 HydrophobicContact CB-CG 4.29Å; Y319-L647 HydrophobicContact CD1-CD1 3.64Å; Y319-L647 HydrophobicContact CD2-CD1 4.49Å; Y319-L647 HydrophobicContact CE1-CB 4.04Å; Y319-L647 HydrophobicContact CE1-CD1 3.69Å; Y319-L647 HydrophobicContact CE1-CG 4.49Å; Y319-L647 HydrophobicContact CE2-CB 4.43Å; Y319-L647 HydrophobicContact CG-CD1 4.05Å; Y319-L647 PolarHBondContact OH-N 3.27Å; N643-L647 VanDerWaalsContact O-CB 3.3Å; N643-L647 WeakPolarHBondContact O-CB 3.34Å; N643-L647 PolarHBondContact O-N 3.46Å; A644-L647 PolarHBondContact O-N 2.95Å; I645-L647 VanDerWaalsContact C-N 3.35Å; I645-L647 PolarHBondContact O-N 3.33Å; L647-A649 VanDerWaalsContact C-N 3.32Å; L647-A649 PolarHBondContact O-N 2.65Å; L647-V650 PolarHBondContact O-N 3.18Å; L647-V651 HydrophobicContact CD1-CG2 4.44Å; L647-V651 VanDerWaalsContact O-CG2 3.31Å; L647-V651 WeakPolarHBondContact O-CG2 3.44Å; L647-V651 PolarHBondContact O-N 3.42Å
648	L	96.4	Very high	96.1	Very high	68 Å²	68	61.6 Å²	61.6	36%	0.356	34%	0.34	S	S	.	.	H	α-helix	trans	-63.8	-37.6	179.5	-68.8	174.2	0	0	0	111.9	V107 A644 I645 L646 V651 V652	V107-L648 HydrophobicContact CG1-CD2 4.39Å; V107-L648 HydrophobicContact CG2-CD2 4.36Å; A644-L648 VanDerWaalsContact O-CG 3.32Å; A644-L648 WeakPolarHBondContact O-CG 3.22Å; A644-L648 PolarHBondContact O-N 3.47Å; I645-L648 PolarHBondContact O-N 3.36Å; L646-L648 PolarHBondContact O-N 3Å; L648-V651 PolarHBondContact O-N 2.96Å; L648-V652 WeakPolarHBondContact O-CG2 3.24Å; L648-V652 PolarHBondContact O-N 2.89Å
649	A	97.2	Very high	95.7	Very high	61 Å²	61	61.9 Å²	61.9	50%	0.504	34%	0.343	S	S	.	.	H	α-helix	trans	-63.3	-41.9	174.7	0	0	0	0	0	111.9	I645 L646 L647 V652 F653	I645-A649 WeakPolarHBondContact O-CB 3.31Å; I645-A649 PolarHBondContact O-N 3.05Å; L646-A649 PolarHBondContact O-N 3.22Å; L647-A649 VanDerWaalsContact C-N 3.32Å; L647-A649 PolarHBondContact O-N 2.65Å; A649-V652 PolarHBondContact O-N 3.06Å; A649-F653 WeakPolarHBondContact O-CB 3.25Å; A649-F653 PolarHBondContact O-N 3.29Å
650	V	96.5	Very high	95.7	Very high	55 Å²	55	61.7 Å²	61.7	33%	0.333	34%	0.343	S	S	.	.	H	α-helix	trans	-62.7	-45	173.9	172.5	0	0	0	0	110.8	L322 L646 L647 V652 F653 I654	L322-V650 HydrophobicContact CD1-CG1 3.75Å; L646-V650 WeakPolarHBondContact O-CG2 3.46Å; L646-V650 PolarHBondContact O-N 3.09Å; L647-V650 PolarHBondContact O-N 3.18Å; V650-V652 PolarHBondContact O-N 3.18Å; V650-F653 WeakPolarHBondContact O-CB 3.37Å; V650-F653 PolarHBondContact O-N 3.39Å; V650-I654 HydrophobicContact CG1-CG2 4.39Å; V650-I654 WeakPolarHBondContact O-CG1 3.48Å; V650-I654 WeakPolarHBondContact O-CG2 3.29Å; V650-I654 PolarHBondContact O-N 3.43Å
651	V	94.9	Very high	95.6	Very high	5 Å²	5	64.6 Å²	64.6	3%	0.03	36%	0.359	C	S	.	.	H	α-helix	trans	-60.1	-45.8	177.4	173.9	0	0	0	0	111	V107 L322 L647 L648 F653 I654 Y655	V107-V651 HydrophobicContact CG2-CG1 3.91Å; L322-V651 HydrophobicContact CD2-CG2 4.12Å; L647-V651 HydrophobicContact CD1-CG2 4.44Å; L647-V651 VanDerWaalsContact O-CG2 3.31Å; L647-V651 WeakPolarHBondContact O-CG2 3.44Å; L647-V651 PolarHBondContact O-N 3.42Å; L648-V651 PolarHBondContact O-N 2.96Å; V651-F653 VanDerWaalsContact C-N 3.32Å; V651-F653 PolarHBondContact O-N 3.48Å; V651-I654 WeakPolarHBondContact O-CG1 3.28Å; V651-I654 PolarHBondContact O-N 3.28Å; V651-Y655 HydrophobicContact CG1-CD2 3.77Å; V651-Y655 HydrophobicContact CG1-CE2 3.82Å; V651-Y655 VanDerWaalsContact O-CD2 3.3Å; V651-Y655 WeakPolarHBondContact O-CD2 3.13Å; V651-Y655 PolarHBondContact O-N 3.13Å
652	V	95.4	Very high	95.5	Very high	108 Å²	108	65.4 Å²	65.4	66%	0.655	36%	0.364	S	S	*	.	H	α-helix	trans	-62.1	-42	176.9	171.5	0	0	0	0	111.1	L648 A649 V650 G656	L648-V652 WeakPolarHBondContact O-CG2 3.24Å; L648-V652 PolarHBondContact O-N 2.89Å; A649-V652 PolarHBondContact O-N 3.06Å; V650-V652 PolarHBondContact O-N 3.18Å; V652-G656 PolarHBondContact O-N 3.44Å
653	F	96.1	Very high	95.4	Very high	141 Å²	141	62.6 Å²	62.6	62%	0.618	35%	0.351	S	S	*	.	H	α-helix	trans	-61.3	-48.8	177.6	174.6	-95.1	0	0	0	112.4	A649 V650 V651 Y655 G656 Y657	A649-F653 WeakPolarHBondContact O-CB 3.25Å; A649-F653 PolarHBondContact O-N 3.29Å; V650-F653 WeakPolarHBondContact O-CB 3.37Å; V650-F653 PolarHBondContact O-N 3.39Å; V651-F653 VanDerWaalsContact C-N 3.32Å; V651-F653 PolarHBondContact O-N 3.48Å; F653-Y655 PolarHBondContact O-N 2.87Å; F653-G656 PolarHBondContact O-N 3.18Å; F653-Y657 WeakPolarHBondContact O-CB 3.18Å; F653-Y657 PolarHBondContact O-N 3.12Å
654	I	94.4	Very high	95.3	Very high	25 Å²	25	62.7 Å²	62.7	13%	0.128	35%	0.353	C	S	.	.	H	α-helix	trans	-67.5	-36.8	-178.9	64.6	-176	0	0	0	112	W103 L322 V650 V651 G656 Y657 Y658	W103-I654 HydrophobicContact CD2-CD1 3.64Å; W103-I654 HydrophobicContact CD2-CG1 4.25Å; W103-I654 HydrophobicContact CE3-CD1 3.78Å; W103-I654 HydrophobicContact CE3-CG1 3.85Å; W103-I654 HydrophobicContact CG-CD1 4.23Å; W103-I654 HydrophobicContact CH2-CB 3.8Å; W103-I654 HydrophobicContact CH2-CD1 3.97Å; W103-I654 HydrophobicContact CH2-CG1 3.97Å; W103-I654 HydrophobicContact CZ2-CB 4.35Å; W103-I654 HydrophobicContact CZ2-CD1 3.82Å; W103-I654 HydrophobicContact CZ2-CG1 4.33Å; W103-I654 HydrophobicContact CZ3-CB 3.89Å; W103-I654 HydrophobicContact CZ3-CD1 3.95Å; W103-I654 HydrophobicContact CZ3-CG1 3.71Å; L322-I654 HydrophobicContact CD2-CD1 3.51Å; V650-I654 HydrophobicContact CG1-CG2 4.39Å; V650-I654 WeakPolarHBondContact O-CG1 3.48Å; V650-I654 WeakPolarHBondContact O-CG2 3.29Å; V650-I654 PolarHBondContact O-N 3.43Å; V651-I654 WeakPolarHBondContact O-CG1 3.28Å; V651-I654 PolarHBondContact O-N 3.28Å; I654-G656 VanDerWaalsContact C-N 3.33Å; I654-Y657 PolarHBondContact O-N 2.79Å; I654-Y658 WeakPolarHBondContact O-CD2 3.29Å; I654-Y658 PolarHBondContact O-N 3.24Å; I654-Y658 VanDerWaalsContact O-N 3.17Å
655	Y	93.3	Very high	95.2	Very high	31 Å²	31	66.2 Å²	66.2	12%	0.122	37%	0.371	C	S	.	.	H	α-helix	trans	-63.3	-42.2	173	-93.6	-97	0	0	0	110.8	T100 W103 T104 I265 F266 I279 V651 F653 A659	T100-Y655 HydrophobicContact CG2-CE1 4.41Å; W103-Y655 HydrophobicContact CB-CE2 3.6Å; W103-Y655 AromaticContact CE3-CD2 3.97Å; W103-Y655 HydrophobicContact CE3-CD2 3.97Å; W103-Y655 AromaticContact CE3-CE2 3.95Å; W103-Y655 HydrophobicContact CE3-CE2 3.95Å; W103-Y655 HydrophobicContact CG-CE2 4.46Å; T104-Y655 PolarHBondContact N-OH 3.21Å; T104-Y655 PolarHBondContact OG1-OH 3.19Å; I265-Y655 HydrophobicContact CD1-CD1 3.49Å; I265-Y655 VanDerWaalsContact CD1-CD1 3.49Å; I265-Y655 HydrophobicContact CD1-CE1 4.04Å; I265-Y655 HydrophobicContact CD1-CG 3.98Å; F266-Y655 HydrophobicContact CE1-CD1 4.04Å; F266-Y655 HydrophobicContact CE1-CE1 4.39Å; F266-Y655 AromaticContact CZ-CD1 3.96Å; F266-Y655 HydrophobicContact CZ-CD1 3.96Å; I279-Y655 HydrophobicContact CG2-CE1 4.22Å; V651-Y655 HydrophobicContact CG1-CD2 3.77Å; V651-Y655 HydrophobicContact CG1-CE2 3.82Å; V651-Y655 VanDerWaalsContact O-CD2 3.3Å; V651-Y655 WeakPolarHBondContact O-CD2 3.13Å; V651-Y655 PolarHBondContact O-N 3.13Å; F653-Y655 PolarHBondContact O-N 2.87Å; Y655-A659 WeakPolarHBondContact O-CA 3.48Å; Y655-A659 VanDerWaalsContact O-CB 3.28Å; Y655-A659 WeakPolarHBondContact O-CB 3.41Å; Y655-A659 PolarHBondContact O-N 3.36Å
656	G	94.3	Very high	95.1	Very high	56 Å²	56	62.4 Å²	62.4	58%	0.577	35%	0.354	S	S	*	.	H	α-helix	trans	-67.8	-32	176.7	0	0	0	0	0	114	V652 F653 I654	V652-G656 PolarHBondContact O-N 3.44Å; F653-G656 PolarHBondContact O-N 3.18Å; I654-G656 VanDerWaalsContact C-N 3.33Å
657	Y	94.9	Very high	94.8	Very high	148 Å²	148	59.6 Å²	59.6	58%	0.58	34%	0.341	S	S	*	.	H	α-helix	trans	-72.2	-38.1	179.4	179.3	-93.5	0	0	0	112.8	F653 I654	F653-Y657 WeakPolarHBondContact O-CB 3.18Å; F653-Y657 PolarHBondContact O-N 3.12Å; I654-Y657 PolarHBondContact O-N 2.79Å
658	Y	93.6	Very high	94.6	Very high	24 Å²	24	64.6 Å²	64.6	9%	0.094	37%	0.37	C	S	.	.	H	α-helix	trans	-98.9	3.4	179.5	-69.8	-77.7	0	0	0	114	W103 H264 I265 M325 I654	W103-Y658 AromaticContact CH2-CD2 3.56Å; W103-Y658 HydrophobicContact CH2-CD2 3.56Å; W103-Y658 AromaticContact CH2-CE2 3.89Å; W103-Y658 HydrophobicContact CH2-CE2 3.89Å; W103-Y658 HydrophobicContact CH2-CG 4.49Å; W103-Y658 HydrophobicContact CZ3-CD2 4.06Å; H264-Y658 CarbonylContact C-O 3.58Å; H264-Y658 WeakPolarHBondContact CA-O 3.47Å; I265-Y658 WeakPolarHBondContact CG1-O 3.44Å; I265-Y658 PolarHBondContact N-O 3.08Å; M325-Y658 HydrophobicContact CE-CD1 3.68Å; M325-Y658 HydrophobicContact CE-CD2 3.85Å; M325-Y658 HydrophobicContact CE-CE1 3.24Å; M325-Y658 HydrophobicContact CE-CE2 3.42Å; M325-Y658 VanDerWaalsContact CE-CE2 3.42Å; M325-Y658 HydrophobicContact CE-CG 3.97Å; M325-Y658 WeakPolarHBondContact CE-OH 3.4Å; M325-Y658 HydrophobicContact SD-CD2 4.27Å; M325-Y658 HydrophobicContact SD-CE1 4.42Å; M325-Y658 HydrophobicContact SD-CE2 3.6Å; M325-Y658 VanDerWaalsContact SD-CE2 3.6Å; I654-Y658 WeakPolarHBondContact O-CD2 3.29Å; I654-Y658 PolarHBondContact O-N 3.24Å; I654-Y658 VanDerWaalsContact O-N 3.17Å
659	A	88.8	Confident	94.5	Very high	53 Å²	53	64.3 Å²	64.3	44%	0.438	37%	0.371	S	S	.	.			trans	-53.7	0	-178.8	0	0	0	0	0	112	F266 Y655	F266-A659 VanDerWaalsContact CB-OXT 3.28Å; F266-A659 WeakPolarHBondContact CB-OXT 3.47Å; F266-A659 HydrophobicContact CD2-CB 3.59Å; F266-A659 HydrophobicContact CE2-CB 3.75Å; F266-A659 PolarHBondContact N-OXT 3.13Å; Y655-A659 WeakPolarHBondContact O-CA 3.48Å; Y655-A659 VanDerWaalsContact O-CB 3.28Å; Y655-A659 WeakPolarHBondContact O-CB 3.41Å; Y655-A659 PolarHBondContact O-N 3.36Å

Retrieved 659 of 659 residues in 1673.6 ms (Link to these results)

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