A0A096NJY9_PAPAN Loading...

BAG family molecular chaperone regulator 5

Co-chaperone for HSP/HSP70 proteins. It functions as a nucleotide-exchange factor promoting the release of ADP from HSP70, thereby activating HSP70-mediated protein refolding. Has an essential role in maintaining proteostasis at junctional membrane complexes (JMC), where it may function as a scaffold between the HSPA8 chaperone and JMC proteins enabling correct, HSPA8-dependent JMC protein folding. Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN.

AlphaFold DB , UniProt , Accession A0A096NJY9, Species PAPAN (Papio anubis, Olive baboon), Gene BAG5, Length 488 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	27.3	Very low	25.1	Very low	251 Å²	251	164.4 Å²	164.4	100%	1.236	80%	0.802	S	S	*	*				0	130.2	0	-85.8	171.3	163.6	0	0	108.3
2	R	24.1	Very low	25.5	Very low	216 Å²	216	160.8 Å²	160.8	82%	0.815	80%	0.801	S	S	*	*			trans	-70.3	144.7	175	-69.5	176.9	170.1	162.4	-7.6	110.9
3	F	21.5	Very low	26	Very low	147 Å²	147	162.3 Å²	162.3	65%	0.645	80%	0.8	S	S	*	*				152.7	136.6	104.2	-96.2	-63.9	0	0	0	113.6
4	H	22.7	Very low	26.4	Very low	142 Å²	142	157.4 Å²	157.4	66%	0.657	78%	0.779	S	S	*	*			trans	34.7	139.4	149.1	-63.6	-42.9	0	0	0	121.2
5	W	24	Very low	27.1	Very low	235 Å²	235	160.1 Å²	160.1	89%	0.89	78%	0.776	S	S	*	*				-163.9	152.1	57.1	-91.9	87.4	0	0	0	112.6
6	L	25.2	Very low	27.7	Very low	147 Å²	147	157.1 Å²	157.1	77%	0.77	77%	0.765	S	S	*	*			trans	-72.9	161	160.1	-86.8	156.9	0	0	0	111.1
7	P	28.3	Very low	28.1	Very low	114 Å²	114	155.6 Å²	155.6	74%	0.74	76%	0.757	S	S	*	*				-138.5	125.6	107.7	23.7	-4.3	0	0	0	112.5
8	T	25.8	Very low	28.5	Very low	114 Å²	114	154.3 Å²	154.3	70%	0.699	75%	0.749	S	S	*	*				48.2	115.6	98.8	59.2	0	0	0	0	117.1
9	L	24.1	Very low	29.1	Very low	162 Å²	162	151.8 Å²	151.8	85%	0.848	74%	0.739	S	S	*	*			trans	169.5	101.3	139	-89.8	157.1	0	0	0	106.3
10	S	25.6	Very low	29.5	Very low	91 Å²	91	150.3 Å²	150.3	64%	0.636	73%	0.73	S	S	*	*				71.1	98.3	92.8	72.9	0	0	0	0	113.4
11	E	27.7	Very low	29.9	Very low	189 Å²	189	146.4 Å²	146.4	88%	0.883	72%	0.716	S	S	*	*			trans	-174.1	131.1	133.8	-103.5	170.4	-159.2	0	0	109.1
12	P	30.3	Very low	30.3	Very low	122 Å²	122	137.9 Å²	137.9	79%	0.792	68%	0.68	S	S	*	*			trans	-75.7	129.6	174	30	-29.9	0	0	0	109.9	D14	P12-D14 PolarHBondContact O-N 3.23Å
13	F	31.1	Very low	31	Very low	180 Å²	180	132.4 Å²	132.4	79%	0.789	67%	0.666	S	S	*	*			trans	-68.5	96.9	175.7	-156.4	-95.7	0	0	0	109.4	R15	F13-R15 PolarHBondContact O-N 3.18Å
14	D	31.7	Very low	31.5	Very low	93 Å²	93	133.8 Å²	133.8	50%	0.497	67%	0.667	S	S	.	*			trans	-86.4	98.8	-174.1	-160.4	-9.6	0	0	0	111.2	P12 N16 Q17	P12-D14 PolarHBondContact O-N 3.23Å; D14-N16 PolarHBondContact O-N 2.82Å; D14-N16 VanDerWaalsContact O-N 3.11Å; D14-N16 WeakPolarHBondContact OD1-CB 3.39Å; D14-N16 PolarHBondContact OD1-N 3.42Å; D14-Q17 PolarHBondContact O-N 3.15Å; D14-Q17 VanDerWaalsContact O-N 3.09Å
15	R	37.6	Very low	32	Very low	198 Å²	198	135.4 Å²	135.4	75%	0.747	67%	0.667	S	S	*	*	H	α-helix	trans	-62.9	-11.3	176.7	-87.3	-170.2	-75.4	-134.3	-1.7	113.8	F13	F13-R15 PolarHBondContact O-N 3.18Å
16	N	36.6	Very low	32.5	Very low	112 Å²	112	129.9 Å²	129.9	60%	0.599	65%	0.654	S	S	*	*	H	α-helix	trans	-78.8	-21.8	173.7	-76.3	-31.3	0	0	0	113	D14 E20	D14-N16 PolarHBondContact O-N 2.82Å; D14-N16 VanDerWaalsContact O-N 3.11Å; D14-N16 WeakPolarHBondContact OD1-CB 3.39Å; D14-N16 PolarHBondContact OD1-N 3.42Å; N16-E20 PolarHBondContact O-N 3.2Å
17	Q	34.5	Very low	32.8	Very low	132 Å²	132	132.7 Å²	132.7	62%	0.617	66%	0.655	S	S	*	*	H	α-helix	trans	-79.3	-30.8	-179.6	-145.8	171.4	30.7	0	0	112.3	D14 T21	D14-Q17 PolarHBondContact O-N 3.15Å; D14-Q17 VanDerWaalsContact O-N 3.09Å; Q17-T21 VanDerWaalsContact O-CB 3.28Å; Q17-T21 WeakPolarHBondContact O-CB 3.31Å; Q17-T21 PolarHBondContact O-N 2.69Å; Q17-T21 PolarHBondContact O-OG1 2.98Å
18	E	35.1	Very low	32.9	Very low	132 Å²	132	132 Å²	132	62%	0.617	65%	0.649	S	S	*	*	H	α-helix	trans	-71.9	-33.1	171.9	-78.1	-171.2	153.1	0	0	112.3	T21 C22	E18-T21 PolarHBondContact O-N 2.84Å; E18-C22 WeakPolarHBondContact O-CB 3.49Å; E18-C22 PolarHBondContact O-N 3.22Å
19	L	40	Very low	33.1	Very low	107 Å²	107	133.5 Å²	133.5	56%	0.56	65%	0.652	S	S	*	*	H	α-helix	trans	-70.8	-41.4	173.5	-83.6	161.8	0	0	0	112	T21 C22 I23	L19-T21 VanDerWaalsContact C-N 3.33Å; L19-T21 PolarHBondContact O-N 3.26Å; L19-C22 PolarHBondContact O-N 3.46Å; L19-I23 WeakPolarHBondContact O-CB 3.32Å; L19-I23 VanDerWaalsContact O-CG1 3.23Å; L19-I23 WeakPolarHBondContact O-CG1 3.49Å; L19-I23 PolarHBondContact O-N 2.75Å
20	E	36.1	Very low	33.5	Very low	121 Å²	121	130.4 Å²	130.4	57%	0.565	64%	0.644	S	S	*	*	H	α-helix	trans	-67.2	-33.2	172.2	-78.9	-153.5	157.3	0	0	112.7	N16 R24	N16-E20 PolarHBondContact O-N 3.2Å; E20-R24 VanDerWaalsContact O-CB 3.26Å; E20-R24 WeakPolarHBondContact O-CB 3.48Å; E20-R24 WeakPolarHBondContact O-CG 3.38Å; E20-R24 PolarHBondContact O-N 2.99Å
21	T	39.1	Very low	33.9	Very low	70 Å²	70	129.1 Å²	129.1	43%	0.429	65%	0.645	S	S	.	*	H	α-helix	trans	-73.3	-31.3	175.1	-50.7	0	0	0	0	111.5	Q17 E18 L19 R25	Q17-T21 VanDerWaalsContact O-CB 3.28Å; Q17-T21 WeakPolarHBondContact O-CB 3.31Å; Q17-T21 PolarHBondContact O-N 2.69Å; Q17-T21 PolarHBondContact O-OG1 2.98Å; E18-T21 PolarHBondContact O-N 2.84Å; L19-T21 VanDerWaalsContact C-N 3.33Å; L19-T21 PolarHBondContact O-N 3.26Å; T21-R25 VanDerWaalsContact O-CB 3.31Å; T21-R25 WeakPolarHBondContact O-CB 3.44Å; T21-R25 WeakPolarHBondContact O-CG 3.31Å; T21-R25 PolarHBondContact O-N 3.44Å
22	C	35.7	Very low	33.9	Very low	71 Å²	71	125.3 Å²	125.3	48%	0.48	64%	0.639	S	S	.	*	H	α-helix	trans	-74	-37.9	173.9	-149.8	0	0	0	0	111.6	E18 L19 R25 L26	E18-C22 WeakPolarHBondContact O-CB 3.49Å; E18-C22 PolarHBondContact O-N 3.22Å; L19-C22 PolarHBondContact O-N 3.46Å; C22-R25 PolarHBondContact O-N 3.06Å; C22-L26 WeakPolarHBondContact O-CB 3.45Å; C22-L26 WeakPolarHBondContact O-CG 3.27Å; C22-L26 PolarHBondContact O-N 3.02Å
23	I	37.8	Very low	34	Very low	101 Å²	101	124 Å²	124	52%	0.518	64%	0.638	S	S	.	*	H	α-helix	trans	-70.3	-40	173.5	-67.9	167.1	0	0	0	110.9	L19 L26 W27	L19-I23 WeakPolarHBondContact O-CB 3.32Å; L19-I23 VanDerWaalsContact O-CG1 3.23Å; L19-I23 WeakPolarHBondContact O-CG1 3.49Å; L19-I23 PolarHBondContact O-N 2.75Å; I23-L26 PolarHBondContact O-N 2.93Å; I23-W27 PolarHBondContact O-N 3.25Å
24	R	33.6	Very low	33.7	Very low	177 Å²	177	120.6 Å²	120.6	67%	0.668	64%	0.636	S	S	*	*	H	α-helix	trans	-66.6	-34.2	172	-77.4	-175.4	-176	-158.2	3.5	112.2	E20 W27 T28	E20-R24 VanDerWaalsContact O-CB 3.26Å; E20-R24 WeakPolarHBondContact O-CB 3.48Å; E20-R24 WeakPolarHBondContact O-CG 3.38Å; E20-R24 PolarHBondContact O-N 2.99Å; R24-W27 PolarHBondContact O-N 3.25Å; R24-T28 WeakPolarHBondContact O-CB 3.48Å; R24-T28 WeakPolarHBondContact O-CG2 3.47Å; R24-T28 PolarHBondContact O-N 3.41Å; R24-T28 PolarHBondContact O-OG1 3.22Å
25	R	31.3	Very low	33.5	Very low	175 Å²	175	125 Å²	125	66%	0.66	65%	0.653	S	S	*	*	H	α-helix	trans	-70	-35.4	171.1	-83.4	-178.8	177.9	177.3	1.4	112.8	T21 C22 T28 L29	T21-R25 VanDerWaalsContact O-CB 3.31Å; T21-R25 WeakPolarHBondContact O-CB 3.44Å; T21-R25 WeakPolarHBondContact O-CG 3.31Å; T21-R25 PolarHBondContact O-N 3.44Å; C22-R25 PolarHBondContact O-N 3.06Å; R25-T28 WeakPolarHBondContact CA-OG1 3.47Å; R25-L29 VanDerWaalsContact O-CB 3.31Å; R25-L29 WeakPolarHBondContact O-CB 3.37Å; R25-L29 WeakPolarHBondContact O-CD1 3.27Å; R25-L29 WeakPolarHBondContact O-CG 3.32Å; R25-L29 PolarHBondContact O-N 2.88Å
26	L	34.7	Very low	33.1	Very low	119 Å²	119	121.7 Å²	121.7	62%	0.623	66%	0.655	S	S	*	*	H	α-helix	trans	-70.1	-30.6	173.4	-83.5	157.7	0	0	0	112.6	C22 I23	C22-L26 WeakPolarHBondContact O-CB 3.45Å; C22-L26 WeakPolarHBondContact O-CG 3.27Å; C22-L26 PolarHBondContact O-N 3.02Å; I23-L26 PolarHBondContact O-N 2.93Å
27	W	31.9	Very low	33.1	Very low	206 Å²	206	125 Å²	125	78%	0.78	67%	0.667	S	S	*	*	H	α-helix	trans	-83.7	-31.9	173.3	-96.6	55.1	0	0	0	113.9	I23 R24 S30	I23-W27 PolarHBondContact O-N 3.25Å; R24-W27 PolarHBondContact O-N 3.25Å; W27-S30 PolarHBondContact O-N 3.46Å; W27-S30 PolarHBondContact O-OG 3Å
28	T	30.5	Very low	33.1	Very low	100 Å²	100	126.2 Å²	126.2	61%	0.613	67%	0.672	S	S	*	*	H	α-helix	trans	-80.2	-18.5	175.3	44.9	0	0	0	0	113.8	R24 R25 S30 G31	R24-T28 WeakPolarHBondContact O-CB 3.48Å; R24-T28 WeakPolarHBondContact O-CG2 3.47Å; R24-T28 PolarHBondContact O-N 3.41Å; R24-T28 PolarHBondContact O-OG1 3.22Å; R25-T28 WeakPolarHBondContact CA-OG1 3.47Å; T28-S30 PolarHBondContact O-N 3.2Å; T28-G31 PolarHBondContact O-N 3.28Å
29	L	30.7	Very low	33	Very low	145 Å²	145	127.9 Å²	127.9	76%	0.759	69%	0.686	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.7	-4	166.7	-78.6	162.9	0	0	0	113.6	R25	R25-L29 VanDerWaalsContact O-CB 3.31Å; R25-L29 WeakPolarHBondContact O-CB 3.37Å; R25-L29 WeakPolarHBondContact O-CD1 3.27Å; R25-L29 WeakPolarHBondContact O-CG 3.32Å; R25-L29 PolarHBondContact O-N 2.88Å
30	S	31.9	Very low	32.9	Very low	98 Å²	98	131 Å²	131	69%	0.685	70%	0.695	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93.9	2.5	169.4	81.7	0	0	0	0	113.8	W27 T28	W27-S30 PolarHBondContact O-N 3.46Å; W27-S30 PolarHBondContact O-OG 3Å; T28-S30 PolarHBondContact O-N 3.2Å
31	G	33.9	Very low	32.8	Very low	64 Å²	64	130.1 Å²	130.1	66%	0.66	70%	0.702	S	S	*	*			trans	-132.8	50.3	-178	0	0	0	0	0	112.4	T28	T28-G31 PolarHBondContact O-N 3.28Å
32	S	28.2	Very low	32.9	Very low	108 Å²	108	135.5 Å²	135.5	76%	0.755	72%	0.724	S	S	*	*			trans	-100.6	118.8	163.8	-169.1	0	0	0	0	108.6	C34	S32-C34 PolarHBondContact O-N 2.96Å
33	A	31.5	Very low	33	Very low	94 Å²	94	138.7 Å²	138.7	78%	0.777	74%	0.737	S	S	*	*			trans	-53	106.1	175.4	0	0	0	0	0	110.1	E35	A33-E35 PolarHBondContact O-N 3.41Å
34	C	25.7	Very low	33.5	Very low	109 Å²	109	142.7 Å²	142.7	74%	0.736	76%	0.755	S	S	*	*			trans	-81.4	101.9	159.1	-155.6	0	0	0	0	105.5	S32 T36	S32-C34 PolarHBondContact O-N 2.96Å; C34-T36 VanDerWaalsContact C-N 3.34Å; C34-T36 PolarHBondContact O-N 2.96Å; C34-T36 PolarHBondContact O-OG1 2.99Å
35	E	27.8	Very low	34.2	Very low	186 Å²	186	136.3 Å²	136.3	87%	0.869	74%	0.744	S	S	*	*			trans	-50.4	103.1	166.3	-79.8	176.7	153.1	0	0	108.1	A33 E37	A33-E35 PolarHBondContact O-N 3.41Å; E35-E37 VanDerWaalsContact C-N 3.35Å; E35-E37 PolarHBondContact O-N 3.39Å
36	T	28.3	Very low	35.5	Very low	128 Å²	128	135.8 Å²	135.8	79%	0.785	76%	0.755	S	S	*	*			trans	-89.4	79.4	177.7	19.6	0	0	0	0	107.3	C34 H38	C34-T36 VanDerWaalsContact C-N 3.34Å; C34-T36 PolarHBondContact O-N 2.96Å; C34-T36 PolarHBondContact O-OG1 2.99Å; T36-H38 PolarHBondContact O-N 2.76Å
37	E	37.5	Very low	37.3	Very low	182 Å²	182	136 Å²	136	85%	0.85	75%	0.752	S	S	*	*			trans	-71.5	86.7	148.8	-80.5	-164.4	159.5	0	0	108	E35	E35-E37 VanDerWaalsContact C-N 3.35Å; E35-E37 PolarHBondContact O-N 3.39Å
38	H	33.8	Very low	39.9	Very low	157 Å²	157	128 Å²	128	73%	0.727	72%	0.724	S	S	*	*			trans	-164.8	73.3	145.2	-110.3	63.7	0	0	0	108.9	T36 K40	T36-H38 PolarHBondContact O-N 2.76Å; H38-K40 PolarHBondContact O-N 2.69Å
39	N	34.1	Very low	42.7	Very low	168 Å²	168	128.1 Å²	128.1	90%	0.898	73%	0.726	S	S	*	*			trans	-75.8	80.6	162.8	-149.6	7	0	0	0	107.7
40	K	36.8	Very low	45.6	Very low	173 Å²	173	122 Å²	122	75%	0.752	70%	0.695	S	S	*	*			trans	-91.8	108.5	161.5	-101.5	-178.6	179.7	172.7	0	107.4	H38 M42	H38-K40 PolarHBondContact O-N 2.69Å; K40-M42 PolarHBondContact O-N 3.29Å
41	S	33.8	Very low	48.5	Very low	102 Å²	102	118.8 Å²	118.8	71%	0.713	67%	0.67	S	S	*	*			trans	-35.1	129.8	171.4	54.8	0	0	0	0	112.7	D43	S41-D43 PolarHBondContact O-N 3.03Å
42	M	42.4	Very low	51.2	Low	183 Å²	183	117.4 Å²	117.4	90%	0.901	65%	0.65	S	S	*	*			trans	-58.9	104.1	161.7	-73.6	179.1	171.3	0	0	108.8	K40	K40-M42 PolarHBondContact O-N 3.29Å
43	D	36	Very low	54.4	Low	138 Å²	138	116.2 Å²	116.2	74%	0.738	63%	0.629	S	S	*	*			trans	-88.5	102.5	162.9	-172.5	15.3	0	0	0	107.9	S41 G45	S41-D43 PolarHBondContact O-N 3.03Å; D43-G45 PolarHBondContact O-N 3.38Å
44	M	48.3	Very low	57.4	Low	185 Å²	185	111.9 Å²	111.9	91%	0.911	59%	0.593	S	S	*	*			trans	-78	66.1	173.4	-74.4	-74.9	-75.4	0	0	109.3
45	G	48.5	Very low	60.6	Low	42 Å²	42	110 Å²	110	43%	0.433	57%	0.573	S	S	.	*	S	Bend	trans	-161.7	34.2	-167.1	0	0	0	0	0	117.6	D43	D43-G45 PolarHBondContact O-N 3.38Å
46	N	59.3	Low	63.8	Low	165 Å²	165	105.5 Å²	105.5	88%	0.882	55%	0.553	S	S	*	*			trans	151.7	88.9	153.2	-90.7	-24.9	0	0	0	110.1	H48	N46-H48 PolarHBondContact O-N 3.36Å
47	Q	73.4	Confident	66.9	Low	122 Å²	122	99.4 Å²	99.4	57%	0.57	52%	0.515	S	S	*	.			trans	-66	131.5	163.5	-105.2	174.6	-11.2	0	0	109
48	H	85.3	Confident	69.6	Low	39 Å²	39	94.6 Å²	94.6	18%	0.181	49%	0.492	C	S	.	.			trans	-52.9	136.3	177.3	-163.8	-83.3	0	0	0	110.7	N46 S50 I51 S52 E100 K102 I105	N46-H48 PolarHBondContact O-N 3.36Å; H48-S50 VanDerWaalsContact C-N 3.27Å; H48-S50 PolarHBondContact CE1-OG 3.17Å; H48-S50 VanDerWaalsContact ND1-CB 3.31Å; H48-S50 WeakPolarHBondContact ND1-CB 3.41Å; H48-S50 PolarHBondContact ND1-N 3Å; H48-S50 VanDerWaalsContact ND1-N 3.18Å; H48-S50 PolarHBondContact ND1-OG 2.9Å; H48-S50 VanDerWaalsContact ND1-OG 3.15Å; H48-S50 PolarHBondContact O-N 3.44Å; H48-I51 HydrophobicContact CB-CB 4.11Å; H48-I51 HydrophobicContact CB-CG1 3.94Å; H48-I51 PolarHBondContact O-N 3.18Å; H48-S52 PolarHBondContact O-N 2.95Å; H48-S52 PolarHBondContact O-OG 3.05Å; H48-E100 IonicContact CE1-OE1 2.81Å; H48-E100 PolarHBondContact CE1-OE1 3.25Å; H48-E100 IonicContact NE2-OE1 3.5Å; H48-E100 IonicContact NE2-OE2 3.42Å; H48-E100 PolarHBondContact NE2-OE2 3.24Å; H48-K102 PolarHBondContact CD2-NZ 2.98Å; H48-K102 VanDerWaalsContact CD2-NZ 3.26Å; H48-K102 PolarHBondContact NE2-NZ 3.45Å; H48-I105 HydrophobicContact CB-CD1 4.28Å; H48-I105 VanDerWaalsContact CE1-CD1 3.49Å; H48-I105 WeakPolarHBondContact CE1-CD1 3.47Å; H48-I105 WeakPolarHBondContact ND1-CD1 3.42Å
49	P	89.6	Confident	72.5	Confident	103 Å²	103	94.2 Å²	94.2	67%	0.669	49%	0.489	S	S	*	.	H	α-helix	trans	-52.4	-44.5	179.3	-28.1	34.7	0	0	0	112.8	I51 S52 R53	P49-I51 PolarHBondContact O-N 3.27Å; P49-S52 PolarHBondContact O-N 3.01Å; P49-R53 WeakPolarHBondContact O-CB 3.42Å; P49-R53 PolarHBondContact O-N 3.37Å
50	S	91.6	Very high	75.3	Confident	15 Å²	15	90.2 Å²	90.2	11%	0.105	47%	0.465	C	S	.	.	H	α-helix	trans	-60.2	-38.2	175	-46.2	0	0	0	0	114.1	H48 L54 D98	H48-S50 VanDerWaalsContact C-N 3.27Å; H48-S50 PolarHBondContact CE1-OG 3.17Å; H48-S50 VanDerWaalsContact ND1-CB 3.31Å; H48-S50 WeakPolarHBondContact ND1-CB 3.41Å; H48-S50 PolarHBondContact ND1-N 3Å; H48-S50 VanDerWaalsContact ND1-N 3.18Å; H48-S50 PolarHBondContact ND1-OG 2.9Å; H48-S50 VanDerWaalsContact ND1-OG 3.15Å; H48-S50 PolarHBondContact O-N 3.44Å; S50-L54 WeakPolarHBondContact O-CB 3.14Å; S50-L54 VanDerWaalsContact O-CG 3.27Å; S50-L54 WeakPolarHBondContact O-CG 3.38Å; S50-L54 PolarHBondContact O-N 2.68Å; S50-D98 VanDerWaalsContact CB-O 3.31Å; S50-D98 WeakPolarHBondContact CB-O 3.47Å; S50-D98 PolarHBondContact OG-O 3.44Å
51	I	92.3	Very high	78.1	Confident	32 Å²	32	82.2 Å²	82.2	16%	0.164	43%	0.431	C	S	.	.	H	α-helix	trans	-70.4	-42.9	177.3	-69.1	-65.5	0	0	0	110.2	H48 P49 R53 L54 Q55 I105 A108	H48-I51 HydrophobicContact CB-CB 4.11Å; H48-I51 HydrophobicContact CB-CG1 3.94Å; H48-I51 PolarHBondContact O-N 3.18Å; P49-I51 PolarHBondContact O-N 3.27Å; I51-R53 VanDerWaalsContact C-N 3.32Å; I51-R53 PolarHBondContact O-N 3.07Å; I51-L54 PolarHBondContact O-N 3.4Å; I51-Q55 VanDerWaalsContact O-CG 3.32Å; I51-Q55 WeakPolarHBondContact O-CG 3.43Å; I51-Q55 PolarHBondContact O-N 2.91Å; I51-I105 HydrophobicContact CD1-CB 4.22Å; I51-I105 HydrophobicContact CD1-CG1 3.9Å; I51-I105 HydrophobicContact CD1-CG2 4.22Å; I51-I105 HydrophobicContact CG1-CD1 4.4Å; I51-I105 HydrophobicContact CG1-CG1 3.98Å; I51-A108 HydrophobicContact CD1-CB 3.94Å
52	S	92.3	Very high	81	Confident	34 Å²	34	84.5 Å²	84.5	24%	0.238	43%	0.428	C	S	.	.	H	α-helix	trans	-59.7	-44.8	175.6	-54.2	0	0	0	0	110.9	H48 P49 Q55 E56	H48-S52 PolarHBondContact O-N 2.95Å; H48-S52 PolarHBondContact O-OG 3.05Å; P49-S52 PolarHBondContact O-N 3.01Å; S52-Q55 WeakPolarHBondContact O-CB 3.34Å; S52-Q55 PolarHBondContact O-N 3.47Å; S52-E56 WeakPolarHBondContact O-CG 3.25Å; S52-E56 PolarHBondContact O-N 3.5Å
53	R	93.9	Very high	83.4	Confident	84 Å²	84	79.5 Å²	79.5	32%	0.317	41%	0.411	S	S	.	.	H	α-helix	trans	-62.5	-44.5	177.2	-175.3	59.3	-178.6	153.9	3.7	112.5	P49 I51 Q55 E56 I57 E93 V97	P49-R53 WeakPolarHBondContact O-CB 3.42Å; P49-R53 PolarHBondContact O-N 3.37Å; I51-R53 VanDerWaalsContact C-N 3.32Å; I51-R53 PolarHBondContact O-N 3.07Å; R53-Q55 VanDerWaalsContact C-N 3.29Å; R53-Q55 PolarHBondContact O-N 3.02Å; R53-E56 IonicContact NH1-OE2 2.69Å; R53-E56 PolarHBondContact NH1-OE2 3.33Å; R53-E56 WeakPolarHBondContact O-CB 3.32Å; R53-E56 PolarHBondContact O-N 3.48Å; R53-I57 HydrophobicContact CG-CD1 4.11Å; R53-I57 WeakPolarHBondContact O-CG1 3.47Å; R53-I57 PolarHBondContact O-N 2.98Å; R53-E93 IonicContact CZ-OE2 3.85Å; R53-E93 IonicContact NE-OE2 2.65Å; R53-E93 IonicContact NH2-OE2 3.84Å; R53-E93 PolarHBondContact NH2-OE2 3.44Å; R53-V97 HydrophobicContact CG-CG2 4.24Å
54	L	94.8	Very high	86.2	Confident	3 Å²	3	73.3 Å²	73.3	2%	0.016	38%	0.378	C	S	.	.	H	α-helix	trans	-62	-36.8	175.5	-74.5	168.7	0	0	0	112.1	S50 I51 I57 Q58 I94 V97 I105 A108 R109 A112	S50-L54 WeakPolarHBondContact O-CB 3.14Å; S50-L54 VanDerWaalsContact O-CG 3.27Å; S50-L54 WeakPolarHBondContact O-CG 3.38Å; S50-L54 PolarHBondContact O-N 2.68Å; I51-L54 PolarHBondContact O-N 3.4Å; L54-I57 PolarHBondContact O-N 2.86Å; L54-Q58 WeakPolarHBondContact O-CB 3.34Å; L54-Q58 VanDerWaalsContact O-CG 3.24Å; L54-Q58 WeakPolarHBondContact O-CG 3.24Å; L54-Q58 PolarHBondContact O-N 3.16Å; L54-I94 HydrophobicContact CD2-CG1 4.43Å; L54-I94 HydrophobicContact CD2-CG2 4.21Å; L54-V97 HydrophobicContact CD1-CG1 4.24Å; L54-V97 HydrophobicContact CD2-CB 4.37Å; L54-V97 HydrophobicContact CD2-CG1 4.47Å; L54-V97 HydrophobicContact CD2-CG2 3.95Å; L54-V97 HydrophobicContact CG-CG1 4.12Å; L54-V97 HydrophobicContact CG-CG2 4.2Å; L54-I105 HydrophobicContact CD1-CG2 4.21Å; L54-A108 HydrophobicContact CD1-CB 3.91Å; L54-R109 HydrophobicContact CD1-CB 4.08Å; L54-R109 HydrophobicContact CD2-CB 4.26Å; L54-R109 HydrophobicContact CD2-CG 4.29Å; L54-A112 HydrophobicContact CD2-CB 4.24Å
55	Q	93.6	Very high	88.4	Confident	69 Å²	69	66.9 Å²	66.9	32%	0.322	35%	0.346	S	S	.	.	H	α-helix	trans	-68	-37.8	175.9	-72.4	174	6.4	0	0	112.5	I51 S52 R53 Q58 K59	I51-Q55 VanDerWaalsContact O-CG 3.32Å; I51-Q55 WeakPolarHBondContact O-CG 3.43Å; I51-Q55 PolarHBondContact O-N 2.91Å; S52-Q55 WeakPolarHBondContact O-CB 3.34Å; S52-Q55 PolarHBondContact O-N 3.47Å; R53-Q55 VanDerWaalsContact C-N 3.29Å; R53-Q55 PolarHBondContact O-N 3.02Å; Q55-Q58 PolarHBondContact O-N 2.85Å; Q55-K59 WeakPolarHBondContact O-CG 3.36Å; Q55-K59 PolarHBondContact O-N 3.35Å
56	E	94.1	Very high	90.3	Very high	92 Å²	92	72.9 Å²	72.9	43%	0.43	36%	0.362	S	S	.	.	H	α-helix	trans	-61.4	-50.3	172.7	-71.3	171.4	-177.8	0	0	111.2	S52 R53 Q58 K59 E60	S52-E56 WeakPolarHBondContact O-CG 3.25Å; S52-E56 PolarHBondContact O-N 3.5Å; R53-E56 IonicContact NH1-OE2 2.69Å; R53-E56 PolarHBondContact NH1-OE2 3.33Å; R53-E56 WeakPolarHBondContact O-CB 3.32Å; R53-E56 PolarHBondContact O-N 3.48Å; E56-Q58 VanDerWaalsContact C-N 3.3Å; E56-Q58 PolarHBondContact O-N 2.96Å; E56-K59 WeakPolarHBondContact O-CB 3.41Å; E56-K59 PolarHBondContact O-N 3.26Å; E56-E60 PolarHBondContact O-N 2.95Å
57	I	93.6	Very high	91.9	Very high	0 Å²	0	70 Å²	70	0%	0	34%	0.343	C	S	.	.	H	α-helix	trans	-59.2	-44.1	177.8	-64.8	162.7	0	0	0	110.4	R53 L54 K59 E60 V61 Q90 E93 I94 V97	R53-I57 HydrophobicContact CG-CD1 4.11Å; R53-I57 WeakPolarHBondContact O-CG1 3.47Å; R53-I57 PolarHBondContact O-N 2.98Å; L54-I57 PolarHBondContact O-N 2.86Å; I57-K59 VanDerWaalsContact C-N 3.29Å; I57-K59 PolarHBondContact O-N 3.32Å; I57-E60 WeakPolarHBondContact O-CB 3.31Å; I57-E60 PolarHBondContact O-N 2.91Å; I57-E60 VanDerWaalsContact O-N 3.09Å; I57-V61 HydrophobicContact CG2-CG2 4.17Å; I57-V61 WeakPolarHBondContact O-CG2 3.42Å; I57-V61 PolarHBondContact O-N 3.41Å; I57-Q90 HydrophobicContact CG2-CB 4.01Å; I57-Q90 HydrophobicContact CG2-CG 4.43Å; I57-E93 HydrophobicContact CD1-CB 3.77Å; I57-E93 HydrophobicContact CG1-CB 4.31Å; I57-I94 HydrophobicContact CB-CG1 4.5Å; I57-I94 HydrophobicContact CD1-CG1 4.21Å; I57-I94 HydrophobicContact CG2-CD1 3.86Å; I57-I94 HydrophobicContact CG2-CG1 3.64Å; I57-V97 HydrophobicContact CD1-CG2 4.41Å
58	Q	94.7	Very high	92.9	Very high	80 Å²	80	64.1 Å²	64.1	37%	0.374	32%	0.316	S	S	.	.	H	α-helix	trans	-61.4	-34.1	176.3	-78.2	176.6	-7	0	0	113.1	L54 Q55 E56 K62 A112	L54-Q58 WeakPolarHBondContact O-CB 3.34Å; L54-Q58 VanDerWaalsContact O-CG 3.24Å; L54-Q58 WeakPolarHBondContact O-CG 3.24Å; L54-Q58 PolarHBondContact O-N 3.16Å; Q55-Q58 PolarHBondContact O-N 2.85Å; E56-Q58 VanDerWaalsContact C-N 3.3Å; E56-Q58 PolarHBondContact O-N 2.96Å; Q58-K62 WeakPolarHBondContact O-CB 3.36Å; Q58-K62 PolarHBondContact O-N 3.43Å; Q58-A112 HydrophobicContact CG-CB 4.1Å
59	K	94.8	Very high	93.1	Very high	150 Å²	150	64.3 Å²	64.3	65%	0.652	32%	0.32	S	S	*	.	H	α-helix	trans	-65.6	-41.8	172.8	-72.8	170.1	-175.8	174.3	0	111.2	Q55 E56 I57 K62 S63	Q55-K59 WeakPolarHBondContact O-CG 3.36Å; Q55-K59 PolarHBondContact O-N 3.35Å; E56-K59 WeakPolarHBondContact O-CB 3.41Å; E56-K59 PolarHBondContact O-N 3.26Å; I57-K59 VanDerWaalsContact C-N 3.29Å; I57-K59 PolarHBondContact O-N 3.32Å; K59-K62 PolarHBondContact O-N 2.99Å; K59-S63 PolarHBondContact O-N 3.38Å
60	E	93.5	Very high	93	Very high	83 Å²	83	60.1 Å²	60.1	39%	0.388	30%	0.295	S	S	.	.	H	α-helix	trans	-64.1	-47.3	176	-67.2	-176.1	-157.8	0	0	111.4	E56 I57 K62 S63 V64 Q90	E56-E60 PolarHBondContact O-N 2.95Å; I57-E60 WeakPolarHBondContact O-CB 3.31Å; I57-E60 PolarHBondContact O-N 2.91Å; I57-E60 VanDerWaalsContact O-N 3.09Å; E60-K62 VanDerWaalsContact C-N 3.33Å; E60-K62 PolarHBondContact O-N 3.14Å; E60-S63 WeakPolarHBondContact O-CB 3.41Å; E60-S63 PolarHBondContact O-N 3.27Å; E60-S63 VanDerWaalsContact O-N 3.12Å; E60-S63 PolarHBondContact O-OG 3.24Å; E60-V64 PolarHBondContact O-N 3.32Å; E60-Q90 PolarHBondContact OE2-NE2 3.07Å
61	V	94.6	Very high	93.1	Very high	6 Å²	6	60 Å²	60	4%	0.036	29%	0.293	C	S	.	.	H	α-helix	trans	-57.6	-46.2	175.4	174	0	0	0	0	110.9	I57 S63 V64 E65 Q90 T116 L119	I57-V61 HydrophobicContact CG2-CG2 4.17Å; I57-V61 WeakPolarHBondContact O-CG2 3.42Å; I57-V61 PolarHBondContact O-N 3.41Å; V61-S63 VanDerWaalsContact C-N 3.26Å; V61-S63 PolarHBondContact O-N 3.41Å; V61-V64 WeakPolarHBondContact O-CG2 3.21Å; V61-V64 PolarHBondContact O-N 2.91Å; V61-V64 VanDerWaalsContact O-N 3.15Å; V61-E65 PolarHBondContact O-N 3.45Å; V61-Q90 HydrophobicContact CG2-CB 3.81Å; V61-Q90 HydrophobicContact CG2-CG 3.83Å; V61-T116 HydrophobicContact CG2-CG2 4.49Å; V61-L119 HydrophobicContact CG1-CD1 3.56Å
62	K	94.1	Very high	93.1	Very high	150 Å²	150	59.7 Å²	59.7	65%	0.652	29%	0.293	S	S	*	.	H	α-helix	trans	-64.7	-29.6	178.2	-168.1	168.1	-172.5	173.6	0	113.1	Q58 K59 E60 V64	Q58-K62 WeakPolarHBondContact O-CB 3.36Å; Q58-K62 PolarHBondContact O-N 3.43Å; K59-K62 PolarHBondContact O-N 2.99Å; E60-K62 VanDerWaalsContact C-N 3.33Å; E60-K62 PolarHBondContact O-N 3.14Å; K62-V64 VanDerWaalsContact C-N 3.28Å; K62-V64 PolarHBondContact O-N 2.96Å
63	S	93.9	Very high	93.1	Very high	78 Å²	78	58.4 Å²	58.4	55%	0.545	29%	0.286	S	S	.	.	H	α-helix	trans	-69.5	-24.8	176.6	79.2	0	0	0	0	113.5	K59 E60 V61	K59-S63 PolarHBondContact O-N 3.38Å; E60-S63 WeakPolarHBondContact O-CB 3.41Å; E60-S63 PolarHBondContact O-N 3.27Å; E60-S63 VanDerWaalsContact O-N 3.12Å; E60-S63 PolarHBondContact O-OG 3.24Å; V61-S63 VanDerWaalsContact C-N 3.26Å; V61-S63 PolarHBondContact O-N 3.41Å
64	V	94	Very high	93.1	Very high	8 Å²	8	55.9 Å²	55.9	5%	0.048	28%	0.278	C	S	.	.	H	α-helix	trans	-99.9	-13.7	178.1	-63.1	0	0	0	0	113.6	E60 V61 K62 Q66 Q67 V68 L83 I86 L87	E60-V64 PolarHBondContact O-N 3.32Å; V61-V64 WeakPolarHBondContact O-CG2 3.21Å; V61-V64 PolarHBondContact O-N 2.91Å; V61-V64 VanDerWaalsContact O-N 3.15Å; K62-V64 VanDerWaalsContact C-N 3.28Å; K62-V64 PolarHBondContact O-N 2.96Å; V64-Q66 VanDerWaalsContact C-N 3.35Å; V64-Q66 PolarHBondContact O-N 3.2Å; V64-Q67 WeakPolarHBondContact O-CA 3.39Å; V64-Q67 WeakPolarHBondContact O-CB 3.34Å; V64-Q67 PolarHBondContact O-N 3.41Å; V64-V68 PolarHBondContact O-N 2.92Å; V64-L83 HydrophobicContact CB-CD2 4.43Å; V64-I86 HydrophobicContact CG1-CD1 4.5Å; V64-I86 HydrophobicContact CG1-CG2 4.12Å; V64-I86 HydrophobicContact CG2-CG2 4.46Å; V64-L87 HydrophobicContact CG2-CD2 3.82Å
65	E	94.1	Very high	93	Very high	50 Å²	50	58.2 Å²	58.2	23%	0.234	30%	0.295	C	S	.	.	H	α-helix	trans	-49.8	-50.3	178.4	175.6	171	-146.1	0	0	112.6	V61 Q67 V68 V69 R118 L119	V61-E65 PolarHBondContact O-N 3.45Å; E65-Q67 VanDerWaalsContact C-N 3.27Å; E65-Q67 PolarHBondContact O-N 3.01Å; E65-V68 WeakPolarHBondContact O-CB 3.36Å; E65-V68 PolarHBondContact O-N 3.47Å; E65-V68 VanDerWaalsContact O-N 3.1Å; E65-V69 HydrophobicContact CG-CG2 4.38Å; E65-V69 WeakPolarHBondContact O-CG2 3.11Å; E65-V69 PolarHBondContact O-N 2.93Å; E65-R118 IonicContact OE1-NH2 3.48Å; E65-R118 PolarHBondContact OE1-NH2 3.11Å; E65-L119 HydrophobicContact CB-CD1 4.15Å; E65-L119 HydrophobicContact CB-CD2 4.35Å; E65-L119 HydrophobicContact CG-CD2 3.96Å
66	Q	89.9	Confident	92.9	Very high	168 Å²	168	59.8 Å²	59.8	79%	0.785	31%	0.306	S	S	*	.	H	α-helix	trans	-63.1	-33.3	179.3	-68.9	-177.5	-13.5	0	0	113	V64 V68 G70	V64-Q66 VanDerWaalsContact C-N 3.35Å; V64-Q66 PolarHBondContact O-N 3.2Å; Q66-V68 VanDerWaalsContact C-N 3.32Å; Q66-G70 PolarHBondContact O-N 2.63Å
67	Q	91.4	Very high	92.8	Very high	103 Å²	103	58.2 Å²	58.2	48%	0.481	30%	0.3	S	S	.	.	H	α-helix	trans	-70.1	-32.9	177.1	-64.1	175.3	60.2	0	0	111.4	V64 E65 F71 L83	V64-Q67 WeakPolarHBondContact O-CA 3.39Å; V64-Q67 WeakPolarHBondContact O-CB 3.34Å; V64-Q67 PolarHBondContact O-N 3.41Å; E65-Q67 VanDerWaalsContact C-N 3.27Å; E65-Q67 PolarHBondContact O-N 3.01Å; Q67-F71 WeakPolarHBondContact O-CA 3.35Å; Q67-F71 WeakPolarHBondContact O-CB 3.39Å; Q67-F71 PolarHBondContact O-N 3.01Å; Q67-F71 VanDerWaalsContact O-N 3.09Å; Q67-L83 HydrophobicContact CB-CD1 4.36Å; Q67-L83 HydrophobicContact CB-CD2 3.85Å
68	V	94.6	Very high	92.7	Very high	0 Å²	0	67 Å²	67	0%	0	34%	0.339	C	S	.	.	H	α-helix	trans	-72.5	-50.2	176	171	0	0	0	0	111.2	V64 E65 Q66 G70 F71 L87 L119 E122 L123 N126	V64-V68 PolarHBondContact O-N 2.92Å; E65-V68 WeakPolarHBondContact O-CB 3.36Å; E65-V68 PolarHBondContact O-N 3.47Å; E65-V68 VanDerWaalsContact O-N 3.1Å; Q66-V68 VanDerWaalsContact C-N 3.32Å; V68-G70 PolarHBondContact O-N 3.09Å; V68-F71 VanDerWaalsContact O-CB 3.23Å; V68-F71 WeakPolarHBondContact O-CB 3.45Å; V68-F71 PolarHBondContact O-N 3.45Å; V68-L87 HydrophobicContact CG2-CD1 3.91Å; V68-L119 HydrophobicContact CG1-CB 4.34Å; V68-L119 HydrophobicContact CG1-CD2 4.3Å; V68-L119 VanDerWaalsContact CG1-O 3.31Å; V68-L119 WeakPolarHBondContact CG1-O 3.33Å; V68-E122 HydrophobicContact CG1-CB 4.24Å; V68-E122 HydrophobicContact CG1-CG 4.35Å; V68-L123 HydrophobicContact CG1-CB 3.91Å; V68-N126 PolarHBondContact O-ND2 3.09Å
69	V	90.3	Very high	92.6	Very high	42 Å²	42	68.4 Å²	68.4	26%	0.255	35%	0.348	S	S	.	.	H	α-helix	trans	-59.5	-39.1	178.4	174.2	0	0	0	0	110.8	E65 I184	E65-V69 HydrophobicContact CG-CG2 4.38Å; E65-V69 WeakPolarHBondContact O-CG2 3.11Å; E65-V69 PolarHBondContact O-N 2.93Å; V69-I184 HydrophobicContact CG1-CD1 4.27Å
70	G	87.8	Confident	92.7	Very high	15 Å²	15	62.2 Å²	62.2	16%	0.155	32%	0.321	C	S	.	.	T	Hydrogen-bonded Turn	trans	-87.5	5.1	177.4	0	0	0	0	0	115.2	Q66 V68 S72	Q66-G70 PolarHBondContact O-N 2.63Å; V68-G70 PolarHBondContact O-N 3.09Å; G70-S72 PolarHBondContact O-N 3.33Å
71	F	93.1	Very high	92.8	Very high	13 Å²	13	62.3 Å²	62.3	6%	0.057	32%	0.32	C	S	.	.			trans	-68.3	116	-176.4	-178.8	-100.3	0	0	0	110.7	Q67 V68 G73 D77 N79 Y80 L83 L123 N126 A127 S185	Q67-F71 WeakPolarHBondContact O-CA 3.35Å; Q67-F71 WeakPolarHBondContact O-CB 3.39Å; Q67-F71 PolarHBondContact O-N 3.01Å; Q67-F71 VanDerWaalsContact O-N 3.09Å; V68-F71 VanDerWaalsContact O-CB 3.23Å; V68-F71 WeakPolarHBondContact O-CB 3.45Å; V68-F71 PolarHBondContact O-N 3.45Å; F71-G73 VanDerWaalsContact CE1-O 3.22Å; F71-G73 WeakPolarHBondContact CE1-O 3.2Å; F71-G73 VanDerWaalsContact CZ-C 3.48Å; F71-D77 HydrophobicContact CZ-CB 4.41Å; F71-N79 HydrophobicContact CE2-CB 4.2Å; F71-Y80 AromaticContact CE1-CD2 3.81Å; F71-Y80 HydrophobicContact CE1-CD2 3.81Å; F71-Y80 HydrophobicContact CZ-CD2 4.01Å; F71-Y80 HydrophobicContact CZ-CG 4.3Å; F71-L83 HydrophobicContact CD2-CD1 3.88Å; F71-L83 HydrophobicContact CG-CD1 4.48Å; F71-L123 HydrophobicContact CB-CD1 3.78Å; F71-L123 HydrophobicContact CD1-CD1 3.62Å; F71-L123 HydrophobicContact CD2-CD1 4.03Å; F71-L123 HydrophobicContact CE1-CD1 4.25Å; F71-L123 HydrophobicContact CG-CD1 3.5Å; F71-N126 HydrophobicContact CD1-CB 4.33Å; F71-A127 HydrophobicContact CE1-CB 3.93Å; F71-S185 WeakPolarHBondContact O-CB 3.48Å
72	S	91.8	Very high	92.9	Very high	25 Å²	25	67.7 Å²	67.7	18%	0.175	34%	0.343	C	S	.	.			trans	-111.1	9.3	-177	60.5	0	0	0	0	113.4	G70 R132 S185	G70-S72 PolarHBondContact O-N 3.33Å; S72-R132 PolarHBondContact O-NE 3.32Å; S72-R132 PolarHBondContact O-NH2 2.92Å; S72-S185 WeakPolarHBondContact CB-O 3.42Å
73	G	91.9	Very high	93.1	Very high	8 Å²	8	61 Å²	61	8%	0.082	31%	0.314	C	S	.	.	S	Bend	trans	-87.2	-174.9	-178.2	0	0	0	0	0	114	F71 D77 R132	F71-G73 VanDerWaalsContact CE1-O 3.22Å; F71-G73 WeakPolarHBondContact CE1-O 3.2Å; F71-G73 VanDerWaalsContact CZ-C 3.48Å; G73-D77 WeakPolarHBondContact CA-OD2 3.45Å; G73-R132 PolarHBondContact O-NE 2.92Å
74	L	94.6	Very high	93.3	Very high	30 Å²	30	60.7 Å²	60.7	16%	0.157	30%	0.304	C	S	.	.			trans	-100.4	172.4	170.1	-65.4	175.9	0	0	0	111.2	D76 D77 Y80 R132 Q136	L74-D76 VanDerWaalsContact C-N 3.28Å; L74-D76 WeakPolarHBondContact CB-OD1 3.15Å; L74-D76 PolarHBondContact O-N 3.42Å; L74-D77 PolarHBondContact N-OD2 3.09Å; L74-D77 WeakPolarHBondContact O-CB 3.31Å; L74-D77 PolarHBondContact O-N 3.4Å; L74-Y80 WeakPolarHBondContact O-CB 3.48Å; L74-R132 HydrophobicContact CD2-CG 3.99Å; L74-Q136 HydrophobicContact CD1-CB 4.43Å; L74-Q136 HydrophobicContact CD1-CG 3.79Å
75	S	92.6	Very high	93.4	Very high	52 Å²	52	68.8 Å²	68.8	36%	0.364	33%	0.334	S	S	.	.	T	Hydrogen-bonded Turn	trans	-70.9	-21.4	-177.4	52.7	0	0	0	0	113.7	Y80	S75-Y80 WeakPolarHBondContact O-CD1 3.23Å
76	D	91.5	Very high	93.6	Very high	102 Å²	102	68.7 Å²	68.7	55%	0.545	34%	0.335	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.2	-12.5	175.9	63.6	-38.9	0	0	0	113.4	L74 K81	L74-D76 VanDerWaalsContact C-N 3.28Å; L74-D76 WeakPolarHBondContact CB-OD1 3.15Å; L74-D76 PolarHBondContact O-N 3.42Å; D76-K81 PolarHBondContact O-NZ 3.47Å
77	D	92.4	Very high	94	Very high	60 Å²	60	60.7 Å²	60.7	32%	0.321	30%	0.297	S	S	.	.	S	Bend	trans	-60.7	144.2	-179	-78.3	-25.9	0	0	0	113.1	F71 G73 L74 N79 Y80 K81	F71-D77 HydrophobicContact CZ-CB 4.41Å; G73-D77 WeakPolarHBondContact CA-OD2 3.45Å; L74-D77 PolarHBondContact N-OD2 3.09Å; L74-D77 WeakPolarHBondContact O-CB 3.31Å; L74-D77 PolarHBondContact O-N 3.4Å; D77-N79 PolarHBondContact O-N 2.98Å; D77-Y80 WeakPolarHBondContact O-CB 3.45Å; D77-Y80 PolarHBondContact O-N 2.98Å; D77-K81 PolarHBondContact O-N 3.18Å; D77-K81 VanDerWaalsContact O-N 3.15Å
78	K	92	Very high	94.2	Very high	185 Å²	185	58.1 Å²	58.1	80%	0.804	29%	0.289	S	S	*	.	H	α-helix	trans	-60	-37.2	175.6	-67.2	179.3	-177.9	172.4	0	112	K81 K82	K78-K81 PolarHBondContact O-N 3.45Å; K78-K82 WeakPolarHBondContact O-CB 3.36Å; K78-K82 PolarHBondContact O-N 3.09Å
79	N	91.8	Very high	94.4	Very high	108 Å²	108	64 Å²	64	58%	0.578	31%	0.314	S	S	*	.	H	α-helix	trans	-70.2	-38	179.5	-74.1	-16.3	0	0	0	112	F71 D77 K82 L83	F71-N79 HydrophobicContact CE2-CB 4.2Å; D77-N79 PolarHBondContact O-N 2.98Å; N79-K82 PolarHBondContact O-N 3.22Å; N79-L83 WeakPolarHBondContact O-CG 3.41Å; N79-L83 PolarHBondContact O-N 3.09Å
80	Y	96.5	Very high	94.7	Very high	21 Å²	21	62.2 Å²	62.2	8%	0.082	30%	0.303	C	S	.	.	H	α-helix	trans	-55.6	-56.2	171.2	179.9	-89.3	0	0	0	110.3	F71 L74 S75 D77 K82 L83 E84 L123 A127	F71-Y80 AromaticContact CE1-CD2 3.81Å; F71-Y80 HydrophobicContact CE1-CD2 3.81Å; F71-Y80 HydrophobicContact CZ-CD2 4.01Å; F71-Y80 HydrophobicContact CZ-CG 4.3Å; L74-Y80 WeakPolarHBondContact O-CB 3.48Å; S75-Y80 WeakPolarHBondContact O-CD1 3.23Å; D77-Y80 WeakPolarHBondContact O-CB 3.45Å; D77-Y80 PolarHBondContact O-N 2.98Å; Y80-K82 PolarHBondContact O-N 2.87Å; Y80-L83 PolarHBondContact O-N 3.12Å; Y80-L83 VanDerWaalsContact O-N 3.09Å; Y80-E84 HydrophobicContact CE1-CB 4.36Å; Y80-E84 WeakPolarHBondContact O-CB 3.39Å; Y80-E84 PolarHBondContact O-N 2.99Å; Y80-L123 HydrophobicContact CD2-CD1 4Å; Y80-L123 HydrophobicContact CD2-CD2 4.18Å; Y80-L123 HydrophobicContact CD2-CG 3.77Å; Y80-L123 HydrophobicContact CE2-CD1 4.33Å; Y80-L123 HydrophobicContact CE2-CD2 4.12Å; Y80-L123 HydrophobicContact CE2-CG 3.64Å; Y80-A127 HydrophobicContact CD2-CB 3.71Å; Y80-A127 HydrophobicContact CE2-CB 3.57Å
81	K	97.1	Very high	95.2	Very high	85 Å²	85	63 Å²	63	37%	0.37	30%	0.304	S	S	.	.	H	α-helix	trans	-58.4	-33.7	-179.9	-69.5	168.5	177.7	152.4	0	112.5	D76 D77 K78 R85	D76-K81 PolarHBondContact O-NZ 3.47Å; D77-K81 PolarHBondContact O-N 3.18Å; D77-K81 VanDerWaalsContact O-N 3.15Å; K78-K81 PolarHBondContact O-N 3.45Å; K81-R85 WeakPolarHBondContact O-CB 3.49Å; K81-R85 WeakPolarHBondContact O-CD 3.49Å; K81-R85 WeakPolarHBondContact O-CG 3.44Å; K81-R85 PolarHBondContact O-N 3.29Å; K81-R85 VanDerWaalsContact O-N 3.13Å
82	K	96.6	Very high	95.4	Very high	118 Å²	118	69.1 Å²	69.1	51%	0.513	33%	0.331	S	S	.	.	H	α-helix	trans	-68.3	-49.8	175.7	-177.7	-174.5	173.9	-170.6	0	111.3	K78 N79 Y80 R85 I86	K78-K82 WeakPolarHBondContact O-CB 3.36Å; K78-K82 PolarHBondContact O-N 3.09Å; N79-K82 PolarHBondContact O-N 3.22Å; Y80-K82 PolarHBondContact O-N 2.87Å; K82-R85 PolarHBondContact O-N 3.3Å; K82-I86 HydrophobicContact CG-CD1 4.14Å; K82-I86 VanDerWaalsContact O-CG1 3.31Å; K82-I86 WeakPolarHBondContact O-CG1 3.5Å; K82-I86 PolarHBondContact O-N 3.02Å; K82-I86 VanDerWaalsContact O-N 3.09Å
83	L	97	Very high	95.6	Very high	9 Å²	9	70.8 Å²	70.8	5%	0.047	34%	0.335	C	S	.	.	H	α-helix	trans	-64	-45.3	179.9	-70.5	172.2	0	0	0	111.5	V64 Q67 F71 N79 Y80 R85 I86 L87 L123	V64-L83 HydrophobicContact CB-CD2 4.43Å; Q67-L83 HydrophobicContact CB-CD1 4.36Å; Q67-L83 HydrophobicContact CB-CD2 3.85Å; F71-L83 HydrophobicContact CD2-CD1 3.88Å; F71-L83 HydrophobicContact CG-CD1 4.48Å; N79-L83 WeakPolarHBondContact O-CG 3.41Å; N79-L83 PolarHBondContact O-N 3.09Å; Y80-L83 PolarHBondContact O-N 3.12Å; Y80-L83 VanDerWaalsContact O-N 3.09Å; L83-R85 PolarHBondContact O-N 3.43Å; L83-I86 PolarHBondContact O-N 2.99Å; L83-L87 WeakPolarHBondContact O-CG 3.37Å; L83-L87 PolarHBondContact O-N 3.18Å; L83-L123 HydrophobicContact CB-CD1 4.4Å; L83-L123 HydrophobicContact CB-CD2 3.73Å; L83-L123 HydrophobicContact CD1-CD1 3.96Å
84	E	97.9	Very high	95.8	Very high	72 Å²	72	70.4 Å²	70.4	34%	0.336	33%	0.331	S	S	.	.	H	α-helix	trans	-55	-52.3	175	-178.4	-177.8	-135	0	0	110.9	Y80 I86 L87 T88 L120 L123	Y80-E84 HydrophobicContact CE1-CB 4.36Å; Y80-E84 WeakPolarHBondContact O-CB 3.39Å; Y80-E84 PolarHBondContact O-N 2.99Å; E84-I86 VanDerWaalsContact C-N 3.3Å; E84-I86 PolarHBondContact O-N 3.49Å; E84-L87 PolarHBondContact O-N 3.13Å; E84-T88 WeakPolarHBondContact O-CB 3.39Å; E84-T88 PolarHBondContact O-N 3.43Å; E84-T88 PolarHBondContact O-OG1 3.08Å; E84-L120 HydrophobicContact CG-CD2 4.28Å; E84-L123 HydrophobicContact CB-CD2 4.21Å
85	R	97.6	Very high	95.9	Very high	178 Å²	178	73.5 Å²	73.5	67%	0.672	35%	0.348	S	S	*	.	H	α-helix	trans	-57.8	-40.1	177.2	-75.3	170.5	-167.3	168.6	3	113.2	K81 K82 L83 K89	K81-R85 WeakPolarHBondContact O-CB 3.49Å; K81-R85 WeakPolarHBondContact O-CD 3.49Å; K81-R85 WeakPolarHBondContact O-CG 3.44Å; K81-R85 PolarHBondContact O-N 3.29Å; K81-R85 VanDerWaalsContact O-N 3.13Å; K82-R85 PolarHBondContact O-N 3.3Å; L83-R85 PolarHBondContact O-N 3.43Å; R85-K89 VanDerWaalsContact O-CB 3.25Å; R85-K89 WeakPolarHBondContact O-CB 3.49Å; R85-K89 PolarHBondContact O-N 2.97Å
86	I	97	Very high	96	Very high	49 Å²	49	75 Å²	75	25%	0.251	36%	0.359	S	S	.	.	H	α-helix	trans	-63.5	-51.8	178.1	-68.3	163.3	0	0	0	109.5	V64 K82 L83 E84 K89 Q90	V64-I86 HydrophobicContact CG1-CD1 4.5Å; V64-I86 HydrophobicContact CG1-CG2 4.12Å; V64-I86 HydrophobicContact CG2-CG2 4.46Å; K82-I86 HydrophobicContact CG-CD1 4.14Å; K82-I86 VanDerWaalsContact O-CG1 3.31Å; K82-I86 WeakPolarHBondContact O-CG1 3.5Å; K82-I86 PolarHBondContact O-N 3.02Å; K82-I86 VanDerWaalsContact O-N 3.09Å; L83-I86 PolarHBondContact O-N 2.99Å; E84-I86 VanDerWaalsContact C-N 3.3Å; E84-I86 PolarHBondContact O-N 3.49Å; I86-K89 WeakPolarHBondContact O-CB 3.27Å; I86-K89 PolarHBondContact O-N 2.99Å; I86-Q90 WeakPolarHBondContact O-CG 3.43Å; I86-Q90 PolarHBondContact O-N 2.87Å
87	L	97.8	Very high	96.2	Very high	0 Å²	0	70.6 Å²	70.6	0%	0	34%	0.336	C	S	.	.	H	α-helix	trans	-64.8	-43.4	-178	-67.9	168.6	0	0	0	112.3	V64 V68 L83 E84 K89 Q90 L91 T116 L119 L120 L123	V64-L87 HydrophobicContact CG2-CD2 3.82Å; V68-L87 HydrophobicContact CG2-CD1 3.91Å; L83-L87 WeakPolarHBondContact O-CG 3.37Å; L83-L87 PolarHBondContact O-N 3.18Å; E84-L87 PolarHBondContact O-N 3.13Å; L87-K89 VanDerWaalsContact C-N 3.29Å; L87-K89 PolarHBondContact O-N 2.84Å; L87-Q90 PolarHBondContact O-N 2.85Å; L87-Q90 VanDerWaalsContact O-N 3.14Å; L87-L91 PolarHBondContact O-N 3.41Å; L87-T116 HydrophobicContact CB-CG2 4.25Å; L87-T116 HydrophobicContact CD2-CG2 4.2Å; L87-T116 VanDerWaalsContact O-CG2 3.31Å; L87-T116 WeakPolarHBondContact O-CG2 3.45Å; L87-L119 HydrophobicContact CD1-CB 4.11Å; L87-L119 HydrophobicContact CD2-CB 4.09Å; L87-L119 HydrophobicContact CD2-CD1 4.13Å; L87-L120 HydrophobicContact CB-CD1 4.24Å; L87-L120 HydrophobicContact CB-CD2 3.61Å; L87-L120 HydrophobicContact CB-CG 3.69Å; L87-L120 HydrophobicContact CD1-CD2 3.9Å; L87-L120 HydrophobicContact CD1-CG 4Å; L87-L120 HydrophobicContact CG-CD2 4.43Å; L87-L120 HydrophobicContact CG-CG 4.48Å; L87-L123 HydrophobicContact CD1-CD2 4.46Å
88	T	97.5	Very high	96.2	Very high	49 Å²	49	72.8 Å²	72.8	30%	0.301	35%	0.347	S	S	.	.	H	α-helix	trans	-61	-39.9	175	-57.7	0	0	0	0	111.3	E84 L91 F92	E84-T88 WeakPolarHBondContact O-CB 3.39Å; E84-T88 PolarHBondContact O-N 3.43Å; E84-T88 PolarHBondContact O-OG1 3.08Å; T88-L91 PolarHBondContact O-N 2.87Å; T88-F92 HydrophobicContact CG2-CD2 3.94Å; T88-F92 HydrophobicContact CG2-CE2 3.52Å; T88-F92 HydrophobicContact CG2-CZ 4.46Å; T88-F92 WeakPolarHBondContact O-CD2 3.47Å; T88-F92 PolarHBondContact O-N 3.15Å; T88-F92 VanDerWaalsContact O-N 3.11Å
89	K	97.7	Very high	96.2	Very high	122 Å²	122	64.5 Å²	64.5	53%	0.53	31%	0.312	S	S	.	.	H	α-helix	trans	-61	-46.4	172.9	-175.6	-171	175.8	-165.8	0	111.2	R85 I86 L87 L91 F92 E93	R85-K89 VanDerWaalsContact O-CB 3.25Å; R85-K89 WeakPolarHBondContact O-CB 3.49Å; R85-K89 PolarHBondContact O-N 2.97Å; I86-K89 WeakPolarHBondContact O-CB 3.27Å; I86-K89 PolarHBondContact O-N 2.99Å; L87-K89 VanDerWaalsContact C-N 3.29Å; L87-K89 PolarHBondContact O-N 2.84Å; K89-L91 VanDerWaalsContact C-N 3.28Å; K89-L91 PolarHBondContact O-N 3.24Å; K89-F92 PolarHBondContact O-N 2.87Å; K89-E93 WeakPolarHBondContact O-CG 3.42Å; K89-E93 PolarHBondContact O-N 3.32Å
90	Q	97.4	Very high	96.1	Very high	6 Å²	6	64.7 Å²	64.7	3%	0.028	31%	0.309	C	S	.	.	H	α-helix	trans	-61.2	-37.6	177.6	-61.2	-47.6	-32.3	0	0	112.2	I57 E60 V61 I86 L87 E93 I94 T116	I57-Q90 HydrophobicContact CG2-CB 4.01Å; I57-Q90 HydrophobicContact CG2-CG 4.43Å; E60-Q90 PolarHBondContact OE2-NE2 3.07Å; V61-Q90 HydrophobicContact CG2-CB 3.81Å; V61-Q90 HydrophobicContact CG2-CG 3.83Å; I86-Q90 WeakPolarHBondContact O-CG 3.43Å; I86-Q90 PolarHBondContact O-N 2.87Å; L87-Q90 PolarHBondContact O-N 2.85Å; L87-Q90 VanDerWaalsContact O-N 3.14Å; Q90-E93 PolarHBondContact O-N 3.06Å; Q90-I94 WeakPolarHBondContact O-CD1 3.33Å; Q90-I94 WeakPolarHBondContact O-CG1 3.42Å; Q90-I94 PolarHBondContact O-N 3.2Å; Q90-T116 HydrophobicContact CB-CG2 4.24Å
91	L	97.3	Very high	95.7	Very high	31 Å²	31	66.3 Å²	66.3	16%	0.162	33%	0.333	C	S	.	.	H	α-helix	trans	-62	-46.1	176.7	-167.6	65.8	0	0	0	111.6	L87 T88 K89 E93 I94 D95 A113 T116 E117 L120	L87-L91 PolarHBondContact O-N 3.41Å; T88-L91 PolarHBondContact O-N 2.87Å; K89-L91 VanDerWaalsContact C-N 3.28Å; K89-L91 PolarHBondContact O-N 3.24Å; L91-E93 VanDerWaalsContact C-N 3.34Å; L91-E93 PolarHBondContact O-N 3.31Å; L91-I94 PolarHBondContact O-N 3.01Å; L91-D95 PolarHBondContact O-N 2.99Å; L91-A113 HydrophobicContact CD1-CB 4.08Å; L91-T116 HydrophobicContact CB-CG2 4.22Å; L91-E117 HydrophobicContact CD1-CG 3.95Å; L91-E117 HydrophobicContact CD2-CG 4.23Å; L91-L120 HydrophobicContact CD2-CD1 4.49Å
92	F	96.9	Very high	95.4	Very high	142 Å²	142	66 Å²	66	62%	0.623	33%	0.332	S	S	*	.	H	α-helix	trans	-61.2	-40.8	174.1	-75.4	-59.6	0	0	0	112.8	T88 K89 D95 S96	T88-F92 HydrophobicContact CG2-CD2 3.94Å; T88-F92 HydrophobicContact CG2-CE2 3.52Å; T88-F92 HydrophobicContact CG2-CZ 4.46Å; T88-F92 WeakPolarHBondContact O-CD2 3.47Å; T88-F92 PolarHBondContact O-N 3.15Å; T88-F92 VanDerWaalsContact O-N 3.11Å; K89-F92 PolarHBondContact O-N 2.87Å; F92-D95 PolarHBondContact O-N 3.05Å; F92-S96 WeakPolarHBondContact O-CB 3.4Å; F92-S96 PolarHBondContact O-N 3.3Å
93	E	96.5	Very high	95.3	Very high	59 Å²	59	62.6 Å²	62.6	28%	0.276	33%	0.33	S	S	.	.	H	α-helix	trans	-63	-42.2	176.2	-68.4	-75.4	153.7	0	0	111.1	R53 I57 K89 Q90 L91 S96 V97	R53-E93 IonicContact CZ-OE2 3.85Å; R53-E93 IonicContact NE-OE2 2.65Å; R53-E93 IonicContact NH2-OE2 3.84Å; R53-E93 PolarHBondContact NH2-OE2 3.44Å; I57-E93 HydrophobicContact CD1-CB 3.77Å; I57-E93 HydrophobicContact CG1-CB 4.31Å; K89-E93 WeakPolarHBondContact O-CG 3.42Å; K89-E93 PolarHBondContact O-N 3.32Å; Q90-E93 PolarHBondContact O-N 3.06Å; L91-E93 VanDerWaalsContact C-N 3.34Å; L91-E93 PolarHBondContact O-N 3.31Å; E93-S96 PolarHBondContact O-N 3.07Å; E93-S96 PolarHBondContact O-OG 2.77Å; E93-V97 WeakPolarHBondContact O-CG2 3.42Å; E93-V97 PolarHBondContact O-N 3.12Å
94	I	97	Very high	95	Very high	0 Å²	0	66.9 Å²	66.9	0%	0	35%	0.353	C	S	.	.	H	α-helix	trans	-61.1	-45.5	175.7	-68.8	159.8	0	0	0	110.9	L54 I57 Q90 L91 S96 V97 R109 A112 A113 T116	L54-I94 HydrophobicContact CD2-CG1 4.43Å; L54-I94 HydrophobicContact CD2-CG2 4.21Å; I57-I94 HydrophobicContact CB-CG1 4.5Å; I57-I94 HydrophobicContact CD1-CG1 4.21Å; I57-I94 HydrophobicContact CG2-CD1 3.86Å; I57-I94 HydrophobicContact CG2-CG1 3.64Å; Q90-I94 WeakPolarHBondContact O-CD1 3.33Å; Q90-I94 WeakPolarHBondContact O-CG1 3.42Å; Q90-I94 PolarHBondContact O-N 3.2Å; L91-I94 PolarHBondContact O-N 3.01Å; I94-S96 VanDerWaalsContact C-N 3.26Å; I94-S96 PolarHBondContact O-N 3.15Å; I94-V97 WeakPolarHBondContact O-CB 3.48Å; I94-V97 PolarHBondContact O-N 2.88Å; I94-R109 HydrophobicContact CG2-CG 3.57Å; I94-R109 VanDerWaalsContact O-CD 3.27Å; I94-R109 WeakPolarHBondContact O-CD 3.43Å; I94-R109 WeakPolarHBondContact O-CG 3.32Å; I94-A112 HydrophobicContact CD1-CB 3.84Å; I94-A112 HydrophobicContact CG1-CB 4.11Å; I94-A112 HydrophobicContact CG2-CB 4.18Å; I94-A113 HydrophobicContact CG2-CB 3.96Å; I94-T116 WeakPolarHBondContact CD1-OG1 3.2Å
95	D	95.4	Very high	94.8	Very high	95 Å²	95	63.5 Å²	63.5	51%	0.508	34%	0.337	S	S	.	.	H	α-helix	trans	-64.8	-31	179.6	-75.1	-20.2	0	0	0	112.7	L91 F92 V97	L91-D95 PolarHBondContact O-N 2.99Å; F92-D95 PolarHBondContact O-N 3.05Å; D95-V97 VanDerWaalsContact C-N 3.26Å; D95-V97 PolarHBondContact O-N 3.31Å
96	S	95.4	Very high	94.7	Very high	84 Å²	84	59.1 Å²	59.1	59%	0.587	32%	0.324	S	S	*	.	H	α-helix	trans	-73.2	-13.5	177	79.8	0	0	0	0	114.2	F92 E93 I94 D98	F92-S96 WeakPolarHBondContact O-CB 3.4Å; F92-S96 PolarHBondContact O-N 3.3Å; E93-S96 PolarHBondContact O-N 3.07Å; E93-S96 PolarHBondContact O-OG 2.77Å; I94-S96 VanDerWaalsContact C-N 3.26Å; I94-S96 PolarHBondContact O-N 3.15Å; S96-D98 PolarHBondContact O-N 3.11Å
97	V	95	Very high	94.5	Very high	10 Å²	10	61.9 Å²	61.9	6%	0.061	34%	0.336	C	S	.	.			trans	-69.5	117	-179.8	178.6	0	0	0	0	110.4	R53 L54 I57 E93 I94 D95 R109	R53-V97 HydrophobicContact CG-CG2 4.24Å; L54-V97 HydrophobicContact CD1-CG1 4.24Å; L54-V97 HydrophobicContact CD2-CB 4.37Å; L54-V97 HydrophobicContact CD2-CG1 4.47Å; L54-V97 HydrophobicContact CD2-CG2 3.95Å; L54-V97 HydrophobicContact CG-CG1 4.12Å; L54-V97 HydrophobicContact CG-CG2 4.2Å; I57-V97 HydrophobicContact CD1-CG2 4.41Å; E93-V97 WeakPolarHBondContact O-CG2 3.42Å; E93-V97 PolarHBondContact O-N 3.12Å; I94-V97 WeakPolarHBondContact O-CB 3.48Å; I94-V97 PolarHBondContact O-N 2.88Å; D95-V97 VanDerWaalsContact C-N 3.26Å; D95-V97 PolarHBondContact O-N 3.31Å; V97-R109 PolarHBondContact O-NH1 3.27Å; V97-R109 VanDerWaalsContact O-NH1 3.17Å
98	D	93.4	Very high	94.4	Very high	106 Å²	106	62.5 Å²	62.5	57%	0.567	34%	0.341	S	S	*	.			trans	-69.6	131.1	170.8	-169.1	5	0	0	0	110.6	S50 S96 E100	S50-D98 VanDerWaalsContact CB-O 3.31Å; S50-D98 WeakPolarHBondContact CB-O 3.47Å; S50-D98 PolarHBondContact OG-O 3.44Å; S96-D98 PolarHBondContact O-N 3.11Å; D98-E100 PolarHBondContact OD1-N 3.29Å
99	T	90.4	Very high	94.3	Very high	10 Å²	10	63.9 Å²	63.9	6%	0.061	34%	0.341	C	S	.	.			trans	-100.6	-12.3	-178.3	62.5	0	0	0	0	112.4	G101 K102 I105 Q106 R109	T99-G101 PolarHBondContact O-N 3.32Å; T99-K102 VanDerWaalsContact O-CB 3.32Å; T99-K102 WeakPolarHBondContact O-CB 3.44Å; T99-K102 PolarHBondContact O-N 2.67Å; T99-I105 HydrophobicContact CG2-CG2 4.08Å; T99-Q106 HydrophobicContact CG2-CB 4.48Å; T99-Q106 HydrophobicContact CG2-CG 3.81Å; T99-Q106 WeakPolarHBondContact OG1-CG 3.45Å; T99-R109 HydrophobicContact CG2-CB 4.5Å
100	E	90.6	Very high	94.3	Very high	112 Å²	112	64.3 Å²	64.3	52%	0.523	34%	0.343	S	S	.	.	T	Hydrogen-bonded Turn	trans	51.8	24.2	-177	-57.1	175.9	-166.4	0	0	113.5	H48 D98 K102	H48-E100 IonicContact CE1-OE1 2.81Å; H48-E100 PolarHBondContact CE1-OE1 3.25Å; H48-E100 IonicContact NE2-OE1 3.5Å; H48-E100 IonicContact NE2-OE2 3.42Å; H48-E100 PolarHBondContact NE2-OE2 3.24Å; D98-E100 PolarHBondContact OD1-N 3.29Å; E100-K102 HydrophobicContact CB-CD 4.41Å; E100-K102 HydrophobicContact CB-CG 4.42Å; E100-K102 PolarHBondContact O-N 3.24Å; E100-K102 IonicContact OE2-NZ 3.46Å; E100-K102 PolarHBondContact OE2-NZ 3.47Å
101	G	88.2	Confident	94.2	Very high	56 Å²	56	70.2 Å²	70.2	58%	0.577	37%	0.365	S	S	*	.	T	Hydrogen-bonded Turn	trans	71.2	4.7	-173.7	0	0	0	0	0	115.2	T99 G103	T99-G101 PolarHBondContact O-N 3.32Å; G101-G103 PolarHBondContact O-N 3.37Å
102	K	91.7	Very high	94.2	Very high	78 Å²	78	68.8 Å²	68.8	34%	0.339	36%	0.358	S	S	.	.			trans	-75.1	116.5	179.5	-66.2	173.2	173.1	150.9	0	110.5	H48 T99 E100 D104 I105 Q106	H48-K102 PolarHBondContact CD2-NZ 2.98Å; H48-K102 VanDerWaalsContact CD2-NZ 3.26Å; H48-K102 PolarHBondContact NE2-NZ 3.45Å; T99-K102 VanDerWaalsContact O-CB 3.32Å; T99-K102 WeakPolarHBondContact O-CB 3.44Å; T99-K102 PolarHBondContact O-N 2.67Å; E100-K102 HydrophobicContact CB-CD 4.41Å; E100-K102 HydrophobicContact CB-CG 4.42Å; E100-K102 PolarHBondContact O-N 3.24Å; E100-K102 IonicContact OE2-NZ 3.46Å; E100-K102 PolarHBondContact OE2-NZ 3.47Å; K102-D104 VanDerWaalsContact C-N 3.32Å; K102-D104 WeakPolarHBondContact CB-OD1 3.3Å; K102-D104 PolarHBondContact O-N 2.97Å; K102-I105 HydrophobicContact CB-CB 4.3Å; K102-I105 HydrophobicContact CB-CD1 3.88Å; K102-I105 HydrophobicContact CB-CG1 3.82Å; K102-I105 HydrophobicContact CD-CD1 3.58Å; K102-I105 HydrophobicContact CD-CG1 4.34Å; K102-I105 HydrophobicContact CG-CD1 4.34Å; K102-I105 PolarHBondContact O-N 3.48Å; K102-I105 VanDerWaalsContact O-N 3.16Å; K102-Q106 WeakPolarHBondContact O-CG 3.3Å; K102-Q106 PolarHBondContact O-N 3.28Å
103	G	92.7	Very high	94.2	Very high	46 Å²	46	62.7 Å²	62.7	47%	0.474	33%	0.333	S	S	.	.	H	α-helix	trans	-62.6	-33.3	-172	0	0	0	0	0	114.5	G101 Q107	G101-G103 PolarHBondContact O-N 3.37Å; G103-Q107 WeakPolarHBondContact O-CB 3.43Å; G103-Q107 PolarHBondContact O-N 2.88Å
104	D	91.2	Very high	94.2	Very high	100 Å²	100	64.7 Å²	64.7	54%	0.535	34%	0.342	S	S	.	.	H	α-helix	trans	-64.6	-43.1	174	59.6	-35.7	0	0	0	112.1	K102 Q107 A108	K102-D104 VanDerWaalsContact C-N 3.32Å; K102-D104 WeakPolarHBondContact CB-OD1 3.3Å; K102-D104 PolarHBondContact O-N 2.97Å; D104-Q107 PolarHBondContact O-N 3.33Å; D104-A108 WeakPolarHBondContact O-CB 3.25Å; D104-A108 PolarHBondContact O-N 3.29Å
105	I	93.8	Very high	94.2	Very high	0 Å²	0	67.7 Å²	67.7	0%	0	36%	0.356	C	S	.	.	H	α-helix	trans	-69.3	-42.1	176.3	-47.7	-173.5	0	0	0	110.9	H48 I51 L54 T99 K102 Q107 A108 R109	H48-I105 HydrophobicContact CB-CD1 4.28Å; H48-I105 VanDerWaalsContact CE1-CD1 3.49Å; H48-I105 WeakPolarHBondContact CE1-CD1 3.47Å; H48-I105 WeakPolarHBondContact ND1-CD1 3.42Å; I51-I105 HydrophobicContact CD1-CB 4.22Å; I51-I105 HydrophobicContact CD1-CG1 3.9Å; I51-I105 HydrophobicContact CD1-CG2 4.22Å; I51-I105 HydrophobicContact CG1-CD1 4.4Å; I51-I105 HydrophobicContact CG1-CG1 3.98Å; L54-I105 HydrophobicContact CD1-CG2 4.21Å; T99-I105 HydrophobicContact CG2-CG2 4.08Å; K102-I105 HydrophobicContact CB-CB 4.3Å; K102-I105 HydrophobicContact CB-CD1 3.88Å; K102-I105 HydrophobicContact CB-CG1 3.82Å; K102-I105 HydrophobicContact CD-CD1 3.58Å; K102-I105 HydrophobicContact CD-CG1 4.34Å; K102-I105 HydrophobicContact CG-CD1 4.34Å; K102-I105 PolarHBondContact O-N 3.48Å; K102-I105 VanDerWaalsContact O-N 3.16Å; I105-Q107 VanDerWaalsContact C-N 3.3Å; I105-Q107 PolarHBondContact O-N 3.04Å; I105-A108 PolarHBondContact O-N 2.91Å; I105-R109 WeakPolarHBondContact O-CB 3.3Å; I105-R109 PolarHBondContact O-N 3.31Å
106	Q	95.3	Very high	94.3	Very high	86 Å²	86	63.2 Å²	63.2	40%	0.402	33%	0.332	S	S	.	.	H	α-helix	trans	-58.8	-43.3	174.3	-72	-179.8	-7.4	0	0	111.8	T99 K102 R109 K110	T99-Q106 HydrophobicContact CG2-CB 4.48Å; T99-Q106 HydrophobicContact CG2-CG 3.81Å; T99-Q106 WeakPolarHBondContact OG1-CG 3.45Å; K102-Q106 WeakPolarHBondContact O-CG 3.3Å; K102-Q106 PolarHBondContact O-N 3.28Å; Q106-R109 PolarHBondContact O-N 3.34Å; Q106-K110 WeakPolarHBondContact O-CB 3.44Å; Q106-K110 PolarHBondContact O-N 3.38Å
107	Q	94.2	Very high	94.5	Very high	108 Å²	108	64.2 Å²	64.2	51%	0.505	33%	0.328	S	S	.	.	H	α-helix	trans	-67.4	-40.6	178.1	-159.3	-170.2	21.5	0	0	111.5	G103 D104 I105 K110 R111	G103-Q107 WeakPolarHBondContact O-CB 3.43Å; G103-Q107 PolarHBondContact O-N 2.88Å; D104-Q107 PolarHBondContact O-N 3.33Å; I105-Q107 VanDerWaalsContact C-N 3.3Å; I105-Q107 PolarHBondContact O-N 3.04Å; Q107-K110 PolarHBondContact O-N 2.95Å; Q107-R111 WeakPolarHBondContact O-CB 3.34Å; Q107-R111 WeakPolarHBondContact O-CG 3.23Å; Q107-R111 PolarHBondContact O-N 3.21Å
108	A	93.9	Very high	94.6	Very high	13 Å²	13	68.9 Å²	68.9	11%	0.107	35%	0.345	C	S	.	.	H	α-helix	trans	-62.4	-44.9	175.3	0	0	0	0	0	111.9	I51 L54 D104 I105 R111 A112	I51-A108 HydrophobicContact CD1-CB 3.94Å; L54-A108 HydrophobicContact CD1-CB 3.91Å; D104-A108 WeakPolarHBondContact O-CB 3.25Å; D104-A108 PolarHBondContact O-N 3.29Å; I105-A108 PolarHBondContact O-N 2.91Å; A108-R111 PolarHBondContact O-N 2.96Å; A108-A112 PolarHBondContact O-N 3.06Å
109	R	97.2	Very high	94.8	Very high	77 Å²	77	63.9 Å²	63.9	29%	0.291	32%	0.318	S	S	.	.	H	α-helix	trans	-60	-48.4	175.3	-170.6	-178.5	69.1	179	5.6	111.3	L54 I94 V97 T99 I105 Q106 R111 A112 A113	L54-R109 HydrophobicContact CD1-CB 4.08Å; L54-R109 HydrophobicContact CD2-CB 4.26Å; L54-R109 HydrophobicContact CD2-CG 4.29Å; I94-R109 HydrophobicContact CG2-CG 3.57Å; I94-R109 VanDerWaalsContact O-CD 3.27Å; I94-R109 WeakPolarHBondContact O-CD 3.43Å; I94-R109 WeakPolarHBondContact O-CG 3.32Å; V97-R109 PolarHBondContact O-NH1 3.27Å; V97-R109 VanDerWaalsContact O-NH1 3.17Å; T99-R109 HydrophobicContact CG2-CB 4.5Å; I105-R109 WeakPolarHBondContact O-CB 3.3Å; I105-R109 PolarHBondContact O-N 3.31Å; Q106-R109 PolarHBondContact O-N 3.34Å; R109-R111 VanDerWaalsContact C-N 3.34Å; R109-R111 PolarHBondContact O-N 3.46Å; R109-A112 PolarHBondContact O-N 2.75Å; R109-A113 PolarHBondContact O-N 3.46Å
110	K	96.6	Very high	95.2	Very high	132 Å²	132	65 Å²	65	57%	0.574	32%	0.323	S	S	*	.	H	α-helix	trans	-58	-45.5	177.4	-176.3	177.7	-179.9	178.9	0	111.8	Q106 Q107 A113 Q114	Q106-K110 WeakPolarHBondContact O-CB 3.44Å; Q106-K110 PolarHBondContact O-N 3.38Å; Q107-K110 PolarHBondContact O-N 2.95Å; K110-A113 PolarHBondContact O-N 3.14Å; K110-Q114 HydrophobicContact CG-CG 4.47Å; K110-Q114 WeakPolarHBondContact O-CB 3.39Å; K110-Q114 VanDerWaalsContact O-CG 3.23Å; K110-Q114 WeakPolarHBondContact O-CG 3.38Å; K110-Q114 PolarHBondContact O-N 2.93Å
111	R	95.3	Very high	95.5	Very high	130 Å²	130	65.7 Å²	65.7	49%	0.491	33%	0.325	S	S	.	.	H	α-helix	trans	-62.6	-42.4	177	-74.4	-174.3	-112.7	131.6	-5.3	111.9	Q107 A108 R109 E115	Q107-R111 WeakPolarHBondContact O-CB 3.34Å; Q107-R111 WeakPolarHBondContact O-CG 3.23Å; Q107-R111 PolarHBondContact O-N 3.21Å; A108-R111 PolarHBondContact O-N 2.96Å; R109-R111 VanDerWaalsContact C-N 3.34Å; R109-R111 PolarHBondContact O-N 3.46Å; R111-E115 WeakPolarHBondContact O-CB 3.47Å; R111-E115 PolarHBondContact O-N 3.46Å; R111-E115 VanDerWaalsContact O-N 3.08Å
112	A	96.6	Very high	95.9	Very high	1 Å²	1	65.4 Å²	65.4	1%	0.008	31%	0.308	C	S	.	.	H	α-helix	trans	-63.6	-43.8	177.3	0	0	0	0	0	112.4	L54 Q58 I94 A108 R109 E115 T116	L54-A112 HydrophobicContact CD2-CB 4.24Å; Q58-A112 HydrophobicContact CG-CB 4.1Å; I94-A112 HydrophobicContact CD1-CB 3.84Å; I94-A112 HydrophobicContact CG1-CB 4.11Å; I94-A112 HydrophobicContact CG2-CB 4.18Å; A108-A112 PolarHBondContact O-N 3.06Å; R109-A112 PolarHBondContact O-N 2.75Å; A112-E115 PolarHBondContact O-N 3.47Å; A112-T116 PolarHBondContact O-N 2.98Å; A112-T116 VanDerWaalsContact O-N 3.09Å; A112-T116 PolarHBondContact O-OG1 2.93Å
113	A	97.8	Very high	96.2	Very high	13 Å²	13	61.7 Å²	61.7	11%	0.107	29%	0.292	C	S	.	.	H	α-helix	trans	-62.7	-49.5	177.8	0	0	0	0	0	111	L91 I94 R109 K110 E115 T116 E117	L91-A113 HydrophobicContact CD1-CB 4.08Å; I94-A113 HydrophobicContact CG2-CB 3.96Å; R109-A113 PolarHBondContact O-N 3.46Å; K110-A113 PolarHBondContact O-N 3.14Å; A113-E115 VanDerWaalsContact C-N 3.28Å; A113-E115 PolarHBondContact O-N 3.11Å; A113-T116 PolarHBondContact O-N 3.24Å; A113-T116 VanDerWaalsContact O-N 3.12Å; A113-E117 WeakPolarHBondContact O-CB 3.48Å; A113-E117 WeakPolarHBondContact O-CG 3.23Å; A113-E117 PolarHBondContact O-N 2.9Å
114	Q	97.4	Very high	96.4	Very high	101 Å²	101	64.6 Å²	64.6	47%	0.472	29%	0.293	S	S	.	.	H	α-helix	trans	-57.4	-40.1	178.2	-74.9	178	-29.2	0	0	112.6	K110 R118	K110-Q114 HydrophobicContact CG-CG 4.47Å; K110-Q114 WeakPolarHBondContact O-CB 3.39Å; K110-Q114 VanDerWaalsContact O-CG 3.23Å; K110-Q114 WeakPolarHBondContact O-CG 3.38Å; K110-Q114 PolarHBondContact O-N 2.93Å; Q114-R118 WeakPolarHBondContact O-CB 3.41Å; Q114-R118 PolarHBondContact O-N 3.25Å
115	E	96.4	Very high	96.6	Very high	63 Å²	63	64.5 Å²	64.5	29%	0.294	29%	0.29	S	S	.	.	H	α-helix	trans	-66.2	-43.6	176.9	-174.2	65.4	179.7	0	0	112.1	R111 A112 A113 R118 L119	R111-E115 WeakPolarHBondContact O-CB 3.47Å; R111-E115 PolarHBondContact O-N 3.46Å; R111-E115 VanDerWaalsContact O-N 3.08Å; A112-E115 PolarHBondContact O-N 3.47Å; A113-E115 VanDerWaalsContact C-N 3.28Å; A113-E115 PolarHBondContact O-N 3.11Å; E115-R118 WeakPolarHBondContact O-CB 3.31Å; E115-R118 PolarHBondContact O-N 3.34Å; E115-R118 IonicContact OE1-CZ 3.35Å; E115-R118 IonicContact OE1-NE 2.71Å; E115-R118 IonicContact OE1-NH1 3.05Å; E115-R118 PolarHBondContact OE1-NH1 2.78Å; E115-R118 IonicContact OE1-NH2 3.15Å; E115-R118 PolarHBondContact OE1-NH2 2.99Å; E115-R118 IonicContact OE2-CZ 2.77Å; E115-R118 IonicContact OE2-NE 2.74Å; E115-R118 IonicContact OE2-NH1 2.82Å; E115-R118 PolarHBondContact OE2-NH1 3.37Å; E115-R118 IonicContact OE2-NH2 3.92Å; E115-L119 WeakPolarHBondContact O-CG 3.22Å; E115-L119 PolarHBondContact O-N 3.47Å; E115-L119 VanDerWaalsContact O-N 3.11Å
116	T	97.9	Very high	96.6	Very high	1 Å²	1	65 Å²	65	1%	0.006	29%	0.292	C	S	.	.	H	α-helix	trans	-66.6	-42.3	179.6	-52.4	0	0	0	0	111.3	V61 L87 Q90 L91 I94 A112 A113 L119 L120	V61-T116 HydrophobicContact CG2-CG2 4.49Å; L87-T116 HydrophobicContact CB-CG2 4.25Å; L87-T116 HydrophobicContact CD2-CG2 4.2Å; L87-T116 VanDerWaalsContact O-CG2 3.31Å; L87-T116 WeakPolarHBondContact O-CG2 3.45Å; Q90-T116 HydrophobicContact CB-CG2 4.24Å; L91-T116 HydrophobicContact CB-CG2 4.22Å; I94-T116 WeakPolarHBondContact CD1-OG1 3.2Å; A112-T116 PolarHBondContact O-N 2.98Å; A112-T116 VanDerWaalsContact O-N 3.09Å; A112-T116 PolarHBondContact O-OG1 2.93Å; A113-T116 PolarHBondContact O-N 3.24Å; A113-T116 VanDerWaalsContact O-N 3.12Å; T116-L119 PolarHBondContact O-N 3.4Å; T116-L120 PolarHBondContact O-N 3.47Å
117	E	98.1	Very high	96.6	Very high	105 Å²	105	60.9 Å²	60.9	49%	0.491	27%	0.273	S	S	.	.	H	α-helix	trans	-62.7	-40.4	173.9	-73	176	172.8	0	0	112.1	L91 A113 L119 L120 K121	L91-E117 HydrophobicContact CD1-CG 3.95Å; L91-E117 HydrophobicContact CD2-CG 4.23Å; A113-E117 WeakPolarHBondContact O-CB 3.48Å; A113-E117 WeakPolarHBondContact O-CG 3.23Å; A113-E117 PolarHBondContact O-N 2.9Å; E117-L119 VanDerWaalsContact C-N 3.31Å; E117-L119 PolarHBondContact O-N 3.14Å; E117-L120 PolarHBondContact O-N 3.48Å; E117-K121 WeakPolarHBondContact O-CB 3.38Å; E117-K121 PolarHBondContact O-N 2.99Å
118	R	97.9	Very high	96.7	Very high	109 Å²	109	59.1 Å²	59.1	41%	0.411	27%	0.267	S	S	.	.	H	α-helix	trans	-57.7	-45.6	174.8	-170.8	-162.7	79.4	-162.6	4.5	110.8	E65 Q114 E115 K121 E122	E65-R118 IonicContact OE1-NH2 3.48Å; E65-R118 PolarHBondContact OE1-NH2 3.11Å; Q114-R118 WeakPolarHBondContact O-CB 3.41Å; Q114-R118 PolarHBondContact O-N 3.25Å; E115-R118 WeakPolarHBondContact O-CB 3.31Å; E115-R118 PolarHBondContact O-N 3.34Å; E115-R118 IonicContact OE1-CZ 3.35Å; E115-R118 IonicContact OE1-NE 2.71Å; E115-R118 IonicContact OE1-NH1 3.05Å; E115-R118 PolarHBondContact OE1-NH1 2.78Å; E115-R118 IonicContact OE1-NH2 3.15Å; E115-R118 PolarHBondContact OE1-NH2 2.99Å; E115-R118 IonicContact OE2-CZ 2.77Å; E115-R118 IonicContact OE2-NE 2.74Å; E115-R118 IonicContact OE2-NH1 2.82Å; E115-R118 PolarHBondContact OE2-NH1 3.37Å; E115-R118 IonicContact OE2-NH2 3.92Å; R118-K121 PolarHBondContact O-N 3.33Å; R118-E122 WeakPolarHBondContact O-CB 2.95Å; R118-E122 PolarHBondContact O-N 2.95Å
119	L	97.9	Very high	96.7	Very high	0 Å²	0	60.1 Å²	60.1	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-67.3	-39.4	178.3	-67.2	177.6	0	0	0	112.8	V61 E65 V68 L87 E115 T116 E117 K121 E122 L123	V61-L119 HydrophobicContact CG1-CD1 3.56Å; E65-L119 HydrophobicContact CB-CD1 4.15Å; E65-L119 HydrophobicContact CB-CD2 4.35Å; E65-L119 HydrophobicContact CG-CD2 3.96Å; V68-L119 HydrophobicContact CG1-CB 4.34Å; V68-L119 HydrophobicContact CG1-CD2 4.3Å; V68-L119 VanDerWaalsContact CG1-O 3.31Å; V68-L119 WeakPolarHBondContact CG1-O 3.33Å; L87-L119 HydrophobicContact CD1-CB 4.11Å; L87-L119 HydrophobicContact CD2-CB 4.09Å; L87-L119 HydrophobicContact CD2-CD1 4.13Å; E115-L119 WeakPolarHBondContact O-CG 3.22Å; E115-L119 PolarHBondContact O-N 3.47Å; E115-L119 VanDerWaalsContact O-N 3.11Å; T116-L119 PolarHBondContact O-N 3.4Å; E117-L119 VanDerWaalsContact C-N 3.31Å; E117-L119 PolarHBondContact O-N 3.14Å; L119-K121 VanDerWaalsContact C-N 3.32Å; L119-K121 PolarHBondContact O-N 3.29Å; L119-E122 PolarHBondContact O-N 3.39Å; L119-L123 WeakPolarHBondContact O-CB 3.36Å; L119-L123 PolarHBondContact O-N 2.9Å
120	L	98.1	Very high	96.6	Very high	35 Å²	35	60.9 Å²	60.9	18%	0.183	28%	0.284	C	S	.	.	H	α-helix	trans	-59	-45.9	173.2	-82.3	167	0	0	0	111.4	E84 L87 L91 T116 E117 E122 L123 E124	E84-L120 HydrophobicContact CG-CD2 4.28Å; L87-L120 HydrophobicContact CB-CD1 4.24Å; L87-L120 HydrophobicContact CB-CD2 3.61Å; L87-L120 HydrophobicContact CB-CG 3.69Å; L87-L120 HydrophobicContact CD1-CD2 3.9Å; L87-L120 HydrophobicContact CD1-CG 4Å; L87-L120 HydrophobicContact CG-CD2 4.43Å; L87-L120 HydrophobicContact CG-CG 4.48Å; L91-L120 HydrophobicContact CD2-CD1 4.49Å; T116-L120 PolarHBondContact O-N 3.47Å; E117-L120 PolarHBondContact O-N 3.48Å; L120-E122 VanDerWaalsContact C-N 3.35Å; L120-E122 PolarHBondContact O-N 3Å; L120-L123 WeakPolarHBondContact O-CB 3.14Å; L120-L123 PolarHBondContact O-N 3.17Å; L120-E124 PolarHBondContact O-N 2.74Å
121	K	97.6	Very high	96.4	Very high	126 Å²	126	57.1 Å²	57.1	55%	0.548	27%	0.269	S	S	.	.	H	α-helix	trans	-63.4	-40.8	177	-172.9	178	-178.4	179.6	0	112	E117 R118 L119 E124 Q125	E117-K121 WeakPolarHBondContact O-CB 3.38Å; E117-K121 PolarHBondContact O-N 2.99Å; R118-K121 PolarHBondContact O-N 3.33Å; L119-K121 VanDerWaalsContact C-N 3.32Å; L119-K121 PolarHBondContact O-N 3.29Å; K121-E124 PolarHBondContact O-N 3.01Å; K121-Q125 WeakPolarHBondContact O-CB 3.45Å; K121-Q125 WeakPolarHBondContact O-CG 3.22Å; K121-Q125 PolarHBondContact O-N 2.94Å
122	E	96.8	Very high	96.4	Very high	50 Å²	50	52 Å²	52	23%	0.234	25%	0.249	C	C	.	.	H	α-helix	trans	-64.8	-41.7	176.6	-174.7	170.5	-177.7	0	0	111.9	V68 R118 L119 L120 E124 Q125 N126	V68-E122 HydrophobicContact CG1-CB 4.24Å; V68-E122 HydrophobicContact CG1-CG 4.35Å; R118-E122 WeakPolarHBondContact O-CB 2.95Å; R118-E122 PolarHBondContact O-N 2.95Å; L119-E122 PolarHBondContact O-N 3.39Å; L120-E122 VanDerWaalsContact C-N 3.35Å; L120-E122 PolarHBondContact O-N 3Å; E122-E124 PolarHBondContact O-N 2.81Å; E122-Q125 PolarHBondContact O-N 3.1Å; E122-N126 WeakPolarHBondContact O-CB 3.24Å; E122-N126 VanDerWaalsContact O-CG 3.31Å; E122-N126 PolarHBondContact O-N 3.01Å; E122-N126 PolarHBondContact O-ND2 2.81Å
123	L	97.4	Very high	96.4	Very high	0 Å²	0	55.3 Å²	55.3	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-58.4	-47.9	174.7	-176.5	62	0	0	0	111.5	V68 F71 Y80 L83 E84 L87 L119 L120 N126 A127	V68-L123 HydrophobicContact CG1-CB 3.91Å; F71-L123 HydrophobicContact CB-CD1 3.78Å; F71-L123 HydrophobicContact CD1-CD1 3.62Å; F71-L123 HydrophobicContact CD2-CD1 4.03Å; F71-L123 HydrophobicContact CE1-CD1 4.25Å; F71-L123 HydrophobicContact CG-CD1 3.5Å; Y80-L123 HydrophobicContact CD2-CD1 4Å; Y80-L123 HydrophobicContact CD2-CD2 4.18Å; Y80-L123 HydrophobicContact CD2-CG 3.77Å; Y80-L123 HydrophobicContact CE2-CD1 4.33Å; Y80-L123 HydrophobicContact CE2-CD2 4.12Å; Y80-L123 HydrophobicContact CE2-CG 3.64Å; L83-L123 HydrophobicContact CB-CD1 4.4Å; L83-L123 HydrophobicContact CB-CD2 3.73Å; L83-L123 HydrophobicContact CD1-CD1 3.96Å; E84-L123 HydrophobicContact CB-CD2 4.21Å; L87-L123 HydrophobicContact CD1-CD2 4.46Å; L119-L123 WeakPolarHBondContact O-CB 3.36Å; L119-L123 PolarHBondContact O-N 2.9Å; L120-L123 WeakPolarHBondContact O-CB 3.14Å; L120-L123 PolarHBondContact O-N 3.17Å; L123-N126 PolarHBondContact O-N 3.46Å; L123-A127 WeakPolarHBondContact O-CB 3.43Å; L123-A127 PolarHBondContact O-N 3.07Å
124	E	96.8	Very high	96.3	Very high	106 Å²	106	58.4 Å²	58.4	50%	0.495	28%	0.279	S	S	.	.	H	α-helix	trans	-62.8	-44.1	177.4	-173.6	-176.4	-172.6	0	0	111.7	L120 K121 E122 N126 A127 N128	L120-E124 PolarHBondContact O-N 2.74Å; K121-E124 PolarHBondContact O-N 3.01Å; E122-E124 PolarHBondContact O-N 2.81Å; E124-N126 VanDerWaalsContact C-N 3.33Å; E124-N126 PolarHBondContact O-N 3.05Å; E124-A127 PolarHBondContact O-N 2.8Å; E124-N128 WeakPolarHBondContact CG-ND2 3.3Å; E124-N128 WeakPolarHBondContact O-CB 3.47Å; E124-N128 PolarHBondContact O-N 3.39Å; E124-N128 PolarHBondContact O-ND2 3.44Å; E124-N128 VanDerWaalsContact O-ND2 3.12Å
125	Q	95.4	Very high	96.2	Very high	99 Å²	99	53.6 Å²	53.6	46%	0.463	26%	0.256	S	S	.	.	H	α-helix	trans	-64.4	-36.1	177.1	-76.4	179.3	-6.4	0	0	112.8	K121 E122 H129	K121-Q125 WeakPolarHBondContact O-CB 3.45Å; K121-Q125 WeakPolarHBondContact O-CG 3.22Å; K121-Q125 PolarHBondContact O-N 2.94Å; E122-Q125 PolarHBondContact O-N 3.1Å; Q125-H129 WeakPolarHBondContact O-CB 3.33Å; Q125-H129 PolarHBondContact O-N 3.02Å; Q125-H129 VanDerWaalsContact O-N 3.17Å
126	N	94.8	Very high	96.1	Very high	9 Å²	9	52.2 Å²	52.2	5%	0.048	25%	0.25	C	C	.	.	H	α-helix	trans	-67.3	-45.1	175.3	-79	-23.9	0	0	0	111.1	V68 F71 E122 L123 E124 S185	V68-N126 PolarHBondContact O-ND2 3.09Å; F71-N126 HydrophobicContact CD1-CB 4.33Å; E122-N126 WeakPolarHBondContact O-CB 3.24Å; E122-N126 VanDerWaalsContact O-CG 3.31Å; E122-N126 PolarHBondContact O-N 3.01Å; E122-N126 PolarHBondContact O-ND2 2.81Å; L123-N126 PolarHBondContact O-N 3.46Å; E124-N126 VanDerWaalsContact C-N 3.33Å; E124-N126 PolarHBondContact O-N 3.05Å; N126-S185 PolarHBondContact OD1-OG 2.87Å
127	A	95.2	Very high	96.1	Very high	1 Å²	1	55.9 Å²	55.9	1%	0.008	27%	0.269	C	S	.	.	H	α-helix	trans	-67	-36.1	-178.7	0	0	0	0	0	113.5	F71 Y80 L123 E124	F71-A127 HydrophobicContact CE1-CB 3.93Å; Y80-A127 HydrophobicContact CD2-CB 3.71Å; Y80-A127 HydrophobicContact CE2-CB 3.57Å; L123-A127 WeakPolarHBondContact O-CB 3.43Å; L123-A127 PolarHBondContact O-N 3.07Å; E124-A127 PolarHBondContact O-N 2.8Å
128	N	94.9	Very high	96	Very high	70 Å²	70	51.4 Å²	51.4	37%	0.374	25%	0.248	S	C	.	.	T	Hydrogen-bonded Turn	trans	-106.3	15.6	-174.1	-58.8	-49.3	0	0	0	113.2	E124	E124-N128 WeakPolarHBondContact CG-ND2 3.3Å; E124-N128 WeakPolarHBondContact O-CB 3.47Å; E124-N128 PolarHBondContact O-N 3.39Å; E124-N128 PolarHBondContact O-ND2 3.44Å; E124-N128 VanDerWaalsContact O-ND2 3.12Å
129	H	94.9	Very high	95.9	Very high	34 Å²	34	47.2 Å²	47.2	16%	0.157	23%	0.233	C	C	.	.			trans	-63.9	137	-178.6	-161.6	-85.2	0	0	0	111.3	Q125 H131 R132 I133 K183 L186	Q125-H129 WeakPolarHBondContact O-CB 3.33Å; Q125-H129 PolarHBondContact O-N 3.02Å; Q125-H129 VanDerWaalsContact O-N 3.17Å; H129-H131 AromaticContact CE1-CD2 3.72Å; H129-H131 PolarHBondContact ND1-N 3.46Å; H129-H131 PolarHBondContact O-N 3.35Å; H129-R132 HydrophobicContact CB-CB 3.83Å; H129-R132 WeakPolarHBondContact O-CA 3.48Å; H129-R132 WeakPolarHBondContact O-CB 3.27Å; H129-R132 PolarHBondContact O-N 3.35Å; H129-I133 WeakPolarHBondContact O-CG1 3.42Å; H129-I133 PolarHBondContact O-N 2.9Å; H129-K183 PolarHBondContact CD2-NZ 3.39Å; H129-K183 PolarHBondContact NE2-NZ 3.31Å; H129-L186 HydrophobicContact CB-CD2 4.2Å
130	P	94.6	Very high	95.8	Very high	93 Å²	93	51.4 Å²	51.4	60%	0.604	25%	0.253	S	S	*	.	H	α-helix	trans	-52.6	-49.1	178.5	-28.9	35.3	0	0	0	113.5	R132 I133 E134	P130-R132 VanDerWaalsContact C-N 3.28Å; P130-R132 PolarHBondContact O-N 2.86Å; P130-I133 WeakPolarHBondContact O-CB 3.35Å; P130-I133 PolarHBondContact O-N 3.12Å; P130-E134 PolarHBondContact O-N 3.49Å
131	H	93	Very high	95.6	Very high	54 Å²	54	54 Å²	54	25%	0.25	26%	0.264	C	S	.	.	H	α-helix	trans	-66.6	-24.1	175.3	-63.8	-46.8	0	0	0	114.3	H129 E134 I135 V178 K179 L186	H129-H131 AromaticContact CE1-CD2 3.72Å; H129-H131 PolarHBondContact ND1-N 3.46Å; H129-H131 PolarHBondContact O-N 3.35Å; H131-E134 IonicContact CE1-OE2 3.22Å; H131-E134 IonicContact CG-OE2 3.4Å; H131-E134 IonicContact ND1-OE2 2.71Å; H131-E134 PolarHBondContact ND1-OE2 3.47Å; H131-I135 WeakPolarHBondContact O-CD1 3.48Å; H131-I135 VanDerWaalsContact O-CG1 3.25Å; H131-I135 WeakPolarHBondContact O-CG1 3.49Å; H131-I135 PolarHBondContact O-N 3.36Å; H131-V178 HydrophobicContact CB-CG1 3.82Å; H131-K179 WeakPolarHBondContact CB-O 3.4Å; H131-K179 PolarHBondContact CD2-O 3.21Å; H131-K179 VanDerWaalsContact CD2-O 3.29Å; H131-L186 HydrophobicContact CB-CD1 4.14Å; H131-L186 HydrophobicContact CB-CD2 4.32Å
132	R	95.1	Very high	95.4	Very high	21 Å²	21	48 Å²	48	8%	0.079	24%	0.238	C	C	.	.	H	α-helix	trans	-70.7	-40.8	172.9	174.3	57.8	-172	91.9	-5.1	110.7	S72 G73 L74 H129 P130 E134 I135 Q136 L186	S72-R132 PolarHBondContact O-NE 3.32Å; S72-R132 PolarHBondContact O-NH2 2.92Å; G73-R132 PolarHBondContact O-NE 2.92Å; L74-R132 HydrophobicContact CD2-CG 3.99Å; H129-R132 HydrophobicContact CB-CB 3.83Å; H129-R132 WeakPolarHBondContact O-CA 3.48Å; H129-R132 WeakPolarHBondContact O-CB 3.27Å; H129-R132 PolarHBondContact O-N 3.35Å; P130-R132 VanDerWaalsContact C-N 3.28Å; P130-R132 PolarHBondContact O-N 2.86Å; R132-E134 VanDerWaalsContact C-N 3.35Å; R132-I135 PolarHBondContact O-N 3.49Å; R132-Q136 PolarHBondContact O-N 3.45Å; R132-Q136 VanDerWaalsContact O-N 3.08Å; R132-L186 HydrophobicContact CB-CD2 3.77Å
133	I	95.4	Very high	95.2	Very high	71 Å²	71	47 Å²	47	36%	0.364	23%	0.233	S	C	.	.	H	α-helix	trans	-66.4	-40.7	174.7	-60.7	165.4	0	0	0	109.7	H129 P130 I135 Q136 N137	H129-I133 WeakPolarHBondContact O-CG1 3.42Å; H129-I133 PolarHBondContact O-N 2.9Å; P130-I133 WeakPolarHBondContact O-CB 3.35Å; P130-I133 PolarHBondContact O-N 3.12Å; I133-I135 PolarHBondContact O-N 3.12Å; I133-Q136 VanDerWaalsContact O-CB 3.31Å; I133-Q136 WeakPolarHBondContact O-CB 3.46Å; I133-Q136 PolarHBondContact O-N 3.38Å; I133-Q136 VanDerWaalsContact O-N 3.12Å; I133-N137 PolarHBondContact O-N 3.08Å; I133-N137 PolarHBondContact O-OD1 2.99Å
134	E	95.9	Very high	94.8	Very high	79 Å²	79	49.7 Å²	49.7	37%	0.369	25%	0.252	S	S	.	.	H	α-helix	trans	-58.3	-48.2	173.9	-174.1	179.7	-172.9	0	0	112.2	P130 H131 R132 Q136 N137 I138 V178	P130-E134 PolarHBondContact O-N 3.49Å; H131-E134 IonicContact CE1-OE2 3.22Å; H131-E134 IonicContact CG-OE2 3.4Å; H131-E134 IonicContact ND1-OE2 2.71Å; H131-E134 PolarHBondContact ND1-OE2 3.47Å; R132-E134 VanDerWaalsContact C-N 3.35Å; E134-Q136 PolarHBondContact O-N 2.88Å; E134-N137 PolarHBondContact O-N 3.09Å; E134-I138 HydrophobicContact CG-CD1 4.11Å; E134-I138 VanDerWaalsContact O-CG1 3.3Å; E134-I138 WeakPolarHBondContact O-CG1 3.4Å; E134-I138 PolarHBondContact O-N 3.29Å; E134-V178 HydrophobicContact CG-CG1 4.46Å; E134-V178 HydrophobicContact CG-CG2 4.09Å
135	I	95.6	Very high	94.4	Very high	0 Å²	0	46.2 Å²	46.2	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-57.1	-41.2	174.1	-69.3	161	0	0	0	110.9	H131 R132 I133 F139 L175 V178 A189 R190 T193	H131-I135 WeakPolarHBondContact O-CD1 3.48Å; H131-I135 VanDerWaalsContact O-CG1 3.25Å; H131-I135 WeakPolarHBondContact O-CG1 3.49Å; H131-I135 PolarHBondContact O-N 3.36Å; R132-I135 PolarHBondContact O-N 3.49Å; I133-I135 PolarHBondContact O-N 3.12Å; I135-F139 WeakPolarHBondContact O-CB 3.36Å; I135-F139 PolarHBondContact O-N 3.4Å; I135-L175 HydrophobicContact CB-CD2 4.4Å; I135-L175 HydrophobicContact CG1-CD2 4.38Å; I135-L175 HydrophobicContact CG2-CD2 4.05Å; I135-V178 HydrophobicContact CD1-CG1 4.13Å; I135-V178 HydrophobicContact CG1-CB 4.14Å; I135-V178 HydrophobicContact CG1-CG1 3.8Å; I135-V178 HydrophobicContact CG1-CG2 4.24Å; I135-A189 HydrophobicContact CD1-CB 4.05Å; I135-R190 HydrophobicContact CD1-CB 3.93Å; I135-T193 HydrophobicContact CG2-CG2 4.3Å; I135-T193 WeakPolarHBondContact CG2-OG1 3.38Å
136	Q	95.9	Very high	94	Very high	34 Å²	34	41.6 Å²	41.6	16%	0.159	22%	0.215	C	C	.	.	H	α-helix	trans	-62.3	-49.6	177.3	-173.7	60.1	32	0	0	111.7	L74 R132 I133 E134 I138 F139 E140	L74-Q136 HydrophobicContact CD1-CB 4.43Å; L74-Q136 HydrophobicContact CD1-CG 3.79Å; R132-Q136 PolarHBondContact O-N 3.45Å; R132-Q136 VanDerWaalsContact O-N 3.08Å; I133-Q136 VanDerWaalsContact O-CB 3.31Å; I133-Q136 WeakPolarHBondContact O-CB 3.46Å; I133-Q136 PolarHBondContact O-N 3.38Å; I133-Q136 VanDerWaalsContact O-N 3.12Å; E134-Q136 PolarHBondContact O-N 2.88Å; Q136-I138 VanDerWaalsContact C-N 3.31Å; Q136-I138 PolarHBondContact O-N 3.09Å; Q136-F139 CarbonylContact O-C 3.57Å; Q136-F139 WeakPolarHBondContact O-CA 3.49Å; Q136-F139 WeakPolarHBondContact O-CB 3.45Å; Q136-F139 PolarHBondContact O-N 2.96Å; Q136-E140 HydrophobicContact CG-CG 4.45Å; Q136-E140 WeakPolarHBondContact CG-OE1 3.35Å; Q136-E140 PolarHBondContact NE2-OE1 3.23Å; Q136-E140 VanDerWaalsContact NE2-OE1 3.08Å; Q136-E140 WeakPolarHBondContact O-CG 3.34Å; Q136-E140 PolarHBondContact O-N 3.04Å
137	N	96.7	Very high	93.5	Very high	78 Å²	78	46.8 Å²	46.8	42%	0.417	23%	0.234	S	C	.	.	H	α-helix	trans	-60.9	-43.1	-177.5	-65.7	-12.6	0	0	0	110.7	I133 E134 F139 E140 E141	I133-N137 PolarHBondContact O-N 3.08Å; I133-N137 PolarHBondContact O-OD1 2.99Å; E134-N137 PolarHBondContact O-N 3.09Å; N137-F139 VanDerWaalsContact C-N 3.3Å; N137-F139 PolarHBondContact O-N 3.27Å; N137-E140 PolarHBondContact O-N 2.84Å; N137-E141 WeakPolarHBondContact O-CG 3.35Å; N137-E141 PolarHBondContact O-N 3.03Å
138	I	96.7	Very high	92.6	Very high	10 Å²	10	53.2 Å²	53.2	5%	0.051	26%	0.264	C	S	.	.	H	α-helix	trans	-64.8	-37.2	176.3	-58	164.1	0	0	0	110.9	E134 Q136 E141 A142 I171 R174 L175 V178	E134-I138 HydrophobicContact CG-CD1 4.11Å; E134-I138 VanDerWaalsContact O-CG1 3.3Å; E134-I138 WeakPolarHBondContact O-CG1 3.4Å; E134-I138 PolarHBondContact O-N 3.29Å; Q136-I138 VanDerWaalsContact C-N 3.31Å; Q136-I138 PolarHBondContact O-N 3.09Å; I138-E141 WeakPolarHBondContact O-CB 3.4Å; I138-E141 PolarHBondContact O-N 3.49Å; I138-A142 PolarHBondContact O-N 3.24Å; I138-A142 VanDerWaalsContact O-N 3.12Å; I138-I171 HydrophobicContact CG2-CG2 3.87Å; I138-R174 HydrophobicContact CD1-CB 4.31Å; I138-L175 HydrophobicContact CB-CD2 3.96Å; I138-L175 HydrophobicContact CB-CG 4.11Å; I138-L175 HydrophobicContact CD1-CD2 4.11Å; I138-L175 HydrophobicContact CD1-CG 4.36Å; I138-L175 HydrophobicContact CG2-CD1 4.01Å; I138-L175 HydrophobicContact CG2-CD2 3.99Å; I138-L175 HydrophobicContact CG2-CG 3.55Å; I138-V178 HydrophobicContact CD1-CG2 3.62Å
139	F	95.3	Very high	91.5	Very high	21 Å²	21	52.6 Å²	52.6	9%	0.092	26%	0.258	C	S	.	.	H	α-helix	trans	-65.4	-38.2	174	-173.5	-124.3	0	0	0	112.4	I135 Q136 N137 A142 Q143 T193 K196 I197 M246	I135-F139 WeakPolarHBondContact O-CB 3.36Å; I135-F139 PolarHBondContact O-N 3.4Å; Q136-F139 CarbonylContact O-C 3.57Å; Q136-F139 WeakPolarHBondContact O-CA 3.49Å; Q136-F139 WeakPolarHBondContact O-CB 3.45Å; Q136-F139 PolarHBondContact O-N 2.96Å; N137-F139 VanDerWaalsContact C-N 3.3Å; N137-F139 PolarHBondContact O-N 3.27Å; F139-A142 WeakPolarHBondContact O-CB 3.47Å; F139-A142 PolarHBondContact O-N 3.45Å; F139-Q143 HydrophobicContact CD1-CG 4.42Å; F139-Q143 HydrophobicContact CE1-CG 4.22Å; F139-Q143 VanDerWaalsContact CE1-NE2 3.32Å; F139-Q143 HydrophobicContact CZ-CG 4.36Å; F139-Q143 WeakPolarHBondContact O-CG 3.35Å; F139-Q143 PolarHBondContact O-N 3.27Å; F139-T193 HydrophobicContact CB-CG2 3.69Å; F139-T193 HydrophobicContact CD2-CG2 3.54Å; F139-T193 HydrophobicContact CE2-CG2 4.41Å; F139-T193 HydrophobicContact CG-CG2 3.82Å; F139-K196 HydrophobicContact CE2-CB 4.46Å; F139-K196 HydrophobicContact CZ-CD 4.35Å; F139-I197 HydrophobicContact CD2-CD1 4.1Å; F139-I197 HydrophobicContact CD2-CG1 4.19Å; F139-I197 HydrophobicContact CE2-CG1 4.3Å; F139-M246 HydrophobicContact CD2-CE 4.18Å; F139-M246 HydrophobicContact CE2-CE 3.68Å; F139-M246 HydrophobicContact CE2-SD 3.94Å; F139-M246 HydrophobicContact CZ-CE 4.3Å; F139-M246 HydrophobicContact CZ-SD 4.45Å
140	E	94.9	Very high	90.1	Very high	89 Å²	89	51.8 Å²	51.8	42%	0.416	25%	0.254	S	S	.	.	H	α-helix	trans	-65.9	-36.9	176	-73.9	173.1	-169.9	0	0	112.3	Q136 N137 A142 Q143 S144	Q136-E140 HydrophobicContact CG-CG 4.45Å; Q136-E140 WeakPolarHBondContact CG-OE1 3.35Å; Q136-E140 PolarHBondContact NE2-OE1 3.23Å; Q136-E140 VanDerWaalsContact NE2-OE1 3.08Å; Q136-E140 WeakPolarHBondContact O-CG 3.34Å; Q136-E140 PolarHBondContact O-N 3.04Å; N137-E140 PolarHBondContact O-N 2.84Å; E140-A142 VanDerWaalsContact C-N 3.33Å; E140-A142 PolarHBondContact O-N 3.44Å; E140-Q143 WeakPolarHBondContact O-CB 3.37Å; E140-Q143 PolarHBondContact O-N 3.22Å; E140-S144 PolarHBondContact O-N 3.17Å
141	E	94.8	Very high	88.1	Confident	89 Å²	89	51.7 Å²	51.7	42%	0.416	25%	0.252	S	S	.	.	H	α-helix	trans	-59.6	-44.9	169.8	-69.7	170.9	-151.4	0	0	111.1	N137 I138 Q143 S144 L145 R174	N137-E141 WeakPolarHBondContact O-CG 3.35Å; N137-E141 PolarHBondContact O-N 3.03Å; I138-E141 WeakPolarHBondContact O-CB 3.4Å; I138-E141 PolarHBondContact O-N 3.49Å; E141-Q143 VanDerWaalsContact C-N 3.34Å; E141-Q143 PolarHBondContact O-N 2.79Å; E141-S144 WeakPolarHBondContact O-CB 3.21Å; E141-S144 PolarHBondContact O-N 3.49Å; E141-L145 WeakPolarHBondContact O-CB 3.37Å; E141-L145 PolarHBondContact O-N 3.29Å; E141-R174 IonicContact OE1-NH1 3.52Å; E141-R174 IonicContact OE2-CZ 3.99Å; E141-R174 IonicContact OE2-NH1 3.9Å; E141-R174 PolarHBondContact OE2-NH1 3.47Å; E141-R174 IonicContact OE2-NH2 3.82Å; E141-R174 PolarHBondContact OE2-NH2 3.11Å
142	A	93.1	Very high	86.2	Confident	0 Å²	0	51.2 Å²	51.2	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-61.6	-42.1	175.2	0	0	0	0	0	112	I138 F139 E140 S144 L145 V146 I171 I197 M246	I138-A142 PolarHBondContact O-N 3.24Å; I138-A142 VanDerWaalsContact O-N 3.12Å; F139-A142 WeakPolarHBondContact O-CB 3.47Å; F139-A142 PolarHBondContact O-N 3.45Å; E140-A142 VanDerWaalsContact C-N 3.33Å; E140-A142 PolarHBondContact O-N 3.44Å; A142-S144 VanDerWaalsContact C-N 3.33Å; A142-S144 PolarHBondContact O-N 3.15Å; A142-L145 PolarHBondContact O-N 3.09Å; A142-V146 WeakPolarHBondContact O-CB 3.4Å; A142-V146 VanDerWaalsContact O-CG2 3.23Å; A142-V146 WeakPolarHBondContact O-CG2 3.46Å; A142-V146 PolarHBondContact O-N 3.11Å; A142-I171 HydrophobicContact CB-CD1 3.93Å; A142-I171 HydrophobicContact CB-CG2 3.92Å; A142-I197 HydrophobicContact CB-CD1 3.85Å; A142-I197 HydrophobicContact CB-CG1 4.2Å; A142-M246 VanDerWaalsContact C-CE 3.45Å; A142-M246 HydrophobicContact CB-CE 3.62Å
143	Q	92.3	Very high	84.2	Confident	29 Å²	29	52.6 Å²	52.6	14%	0.136	26%	0.261	C	S	.	.	H	α-helix	trans	-60	-43.4	174.1	-72.5	177.9	-19.3	0	0	111.4	F139 E140 E141 V146 R147 M246 V248	F139-Q143 HydrophobicContact CD1-CG 4.42Å; F139-Q143 HydrophobicContact CE1-CG 4.22Å; F139-Q143 VanDerWaalsContact CE1-NE2 3.32Å; F139-Q143 HydrophobicContact CZ-CG 4.36Å; F139-Q143 WeakPolarHBondContact O-CG 3.35Å; F139-Q143 PolarHBondContact O-N 3.27Å; E140-Q143 WeakPolarHBondContact O-CB 3.37Å; E140-Q143 PolarHBondContact O-N 3.22Å; E141-Q143 VanDerWaalsContact C-N 3.34Å; E141-Q143 PolarHBondContact O-N 2.79Å; Q143-V146 PolarHBondContact O-N 2.69Å; Q143-R147 WeakPolarHBondContact O-CB 3.36Å; Q143-R147 WeakPolarHBondContact O-CG 3.29Å; Q143-R147 PolarHBondContact O-N 2.88Å; Q143-M246 HydrophobicContact CB-CE 4.37Å; Q143-M246 HydrophobicContact CG-CB 4.37Å; Q143-M246 HydrophobicContact CG-CE 3.86Å; Q143-M246 WeakPolarHBondContact CG-O 3.3Å; Q143-M246 PolarHBondContact NE2-O 2.98Å; Q143-V248 HydrophobicContact CB-CG1 3.81Å; Q143-V248 HydrophobicContact CG-CG1 3.88Å
144	S	90.4	Very high	82	Confident	56 Å²	56	54.7 Å²	54.7	39%	0.392	27%	0.265	S	S	.	.	H	α-helix	trans	-63.2	-49.5	178.2	-164	0	0	0	0	111.3	E140 E141 A142 V146 R147 E148	E140-S144 PolarHBondContact O-N 3.17Å; E141-S144 WeakPolarHBondContact O-CB 3.21Å; E141-S144 PolarHBondContact O-N 3.49Å; A142-S144 VanDerWaalsContact C-N 3.33Å; A142-S144 PolarHBondContact O-N 3.15Å; S144-V146 VanDerWaalsContact C-N 3.27Å; S144-V146 PolarHBondContact O-N 3.07Å; S144-R147 PolarHBondContact O-N 3.25Å; S144-R147 VanDerWaalsContact O-N 3.13Å; S144-E148 WeakPolarHBondContact O-CG 3.44Å; S144-E148 PolarHBondContact O-N 3.4Å
145	L	88.4	Confident	79.4	Confident	33 Å²	33	57.5 Å²	57.5	17%	0.173	28%	0.282	C	S	.	.	H	α-helix	trans	-57.8	-42.3	178.9	-175.1	64.7	0	0	0	111.4	E141 A142 K149 F164 I168 I171	E141-L145 WeakPolarHBondContact O-CB 3.37Å; E141-L145 PolarHBondContact O-N 3.29Å; A142-L145 PolarHBondContact O-N 3.09Å; L145-K149 WeakPolarHBondContact O-CB 3.37Å; L145-K149 VanDerWaalsContact O-CG 3.25Å; L145-K149 WeakPolarHBondContact O-CG 3.33Å; L145-K149 PolarHBondContact O-N 3.22Å; L145-F164 HydrophobicContact CD1-CD2 4.05Å; L145-F164 HydrophobicContact CD2-CD2 4.02Å; L145-F164 HydrophobicContact CD2-CE2 4.19Å; L145-F164 HydrophobicContact CG-CD2 3.64Å; L145-F164 HydrophobicContact CG-CE2 3.81Å; L145-I168 HydrophobicContact CD2-CD1 3.87Å; L145-I168 HydrophobicContact CD2-CG1 3.89Å; L145-I171 HydrophobicContact CD2-CD1 3.9Å
146	V	85.9	Confident	77.1	Confident	2 Å²	2	61 Å²	61	1%	0.012	32%	0.318	C	S	.	.	H	α-helix	trans	-69.6	-42.5	176.4	170.2	0	0	0	0	111.7	A142 Q143 S144 E148 K149 I150 F164 I168 V200 I242 M246	A142-V146 WeakPolarHBondContact O-CB 3.4Å; A142-V146 VanDerWaalsContact O-CG2 3.23Å; A142-V146 WeakPolarHBondContact O-CG2 3.46Å; A142-V146 PolarHBondContact O-N 3.11Å; Q143-V146 PolarHBondContact O-N 2.69Å; S144-V146 VanDerWaalsContact C-N 3.27Å; S144-V146 PolarHBondContact O-N 3.07Å; V146-E148 VanDerWaalsContact C-N 3.34Å; V146-E148 PolarHBondContact O-N 3.47Å; V146-K149 CarbonylContact O-C 3.49Å; V146-K149 PolarHBondContact O-N 3.12Å; V146-K149 VanDerWaalsContact O-N 3.13Å; V146-I150 HydrophobicContact CG1-CD1 3.25Å; V146-I150 HydrophobicContact CG1-CG1 3.63Å; V146-I150 WeakPolarHBondContact O-CB 3.41Å; V146-I150 WeakPolarHBondContact O-CG1 3.01Å; V146-I150 PolarHBondContact O-N 2.83Å; V146-F164 HydrophobicContact CG2-CE2 4.15Å; V146-F164 HydrophobicContact CG2-CZ 4.14Å; V146-I168 HydrophobicContact CG2-CD1 4.3Å; V146-V200 HydrophobicContact CG2-CG1 4.12Å; V146-I242 HydrophobicContact CG1-CG2 3.6Å; V146-M246 HydrophobicContact CB-CG 4.31Å; V146-M246 HydrophobicContact CG1-CG 3.95Å; V146-M246 HydrophobicContact CG2-CE 4.28Å; V146-M246 HydrophobicContact CG2-CG 4.26Å
147	R	83.6	Confident	74.7	Confident	119 Å²	119	61.1 Å²	61.1	45%	0.449	33%	0.329	S	S	.	.	H	α-helix	trans	-58.6	-44.6	176.9	-77.6	175.4	-151	-92.1	5	112	Q143 S144 K149 V248	Q143-R147 WeakPolarHBondContact O-CB 3.36Å; Q143-R147 WeakPolarHBondContact O-CG 3.29Å; Q143-R147 PolarHBondContact O-N 2.88Å; S144-R147 PolarHBondContact O-N 3.25Å; S144-R147 VanDerWaalsContact O-N 3.13Å; R147-K149 PolarHBondContact O-N 3.48Å; R147-V248 HydrophobicContact CG-CB 3.96Å; R147-V248 HydrophobicContact CG-CG1 3.87Å; R147-V248 VanDerWaalsContact NH1-CB 3.32Å; R147-V248 PolarHBondContact NH1-O 3.43Å
148	E	77.3	Confident	72.6	Confident	135 Å²	135	62.6 Å²	62.6	63%	0.631	34%	0.336	S	S	*	.	H	α-helix	trans	-62.3	-32.2	178.4	-72.1	177.4	-171.1	0	0	112.1	S144 V146	S144-E148 WeakPolarHBondContact O-CG 3.44Å; S144-E148 PolarHBondContact O-N 3.4Å; V146-E148 VanDerWaalsContact C-N 3.34Å; V146-E148 PolarHBondContact O-N 3.47Å
149	K	71.1	Confident	70.4	Confident	57 Å²	57	66.4 Å²	66.4	25%	0.248	36%	0.363	C	S	.	.	H	α-helix	trans	-108.4	-0.2	-170.8	-58.3	-84.1	-173.3	172.7	0	114.3	L145 V146 R147 P152 T161 F164	L145-K149 WeakPolarHBondContact O-CB 3.37Å; L145-K149 VanDerWaalsContact O-CG 3.25Å; L145-K149 WeakPolarHBondContact O-CG 3.33Å; L145-K149 PolarHBondContact O-N 3.22Å; V146-K149 CarbonylContact O-C 3.49Å; V146-K149 PolarHBondContact O-N 3.12Å; V146-K149 VanDerWaalsContact O-N 3.13Å; R147-K149 PolarHBondContact O-N 3.48Å; K149-P152 WeakPolarHBondContact O-CD 3.41Å; K149-T161 PolarHBondContact NZ-OG1 3.08Å; K149-F164 HydrophobicContact CB-CD2 3.87Å; K149-F164 HydrophobicContact CB-CE2 4.03Å; K149-F164 HydrophobicContact CD-CB 4.49Å; K149-F164 HydrophobicContact CD-CD2 4.46Å; K149-F164 HydrophobicContact CG-CD2 3.66Å; K149-F164 HydrophobicContact CG-CE2 4.25Å; K149-F164 HydrophobicContact CG-CG 4.41Å
150	I	65.3	Low	68.8	Low	17 Å²	17	66.9 Å²	66.9	9%	0.087	37%	0.368	C	S	.	.	H	α-helix	trans	-77.4	-28.5	173	-84.2	173.2	0	0	0	112.2	V146 P152 F153 Y154 I242 A243 V248	V146-I150 HydrophobicContact CG1-CD1 3.25Å; V146-I150 HydrophobicContact CG1-CG1 3.63Å; V146-I150 WeakPolarHBondContact O-CB 3.41Å; V146-I150 WeakPolarHBondContact O-CG1 3.01Å; V146-I150 PolarHBondContact O-N 2.83Å; I150-P152 VanDerWaalsContact C-N 3.31Å; I150-F153 PolarHBondContact O-N 3.42Å; I150-Y154 HydrophobicContact CG2-CD2 4.36Å; I150-Y154 HydrophobicContact CG2-CE2 3.72Å; I150-I242 HydrophobicContact CD1-CB 4.48Å; I150-I242 HydrophobicContact CD1-CG2 3.81Å; I150-I242 HydrophobicContact CG1-CG2 4.18Å; I150-A243 HydrophobicContact CD1-CB 4.44Å; I150-V248 HydrophobicContact CD1-CG2 4.36Å
151	V	52.7	Low	67.5	Low	92 Å²	92	64.8 Å²	64.8	56%	0.558	36%	0.361	S	S	*	.	G	3₁₀ helix	trans	-53.4	-35.6	-177.3	-178.9	0	0	0	0	114.3	F153	V151-F153 PolarHBondContact O-N 3.05Å
152	P	53.7	Low	66.6	Low	44 Å²	44	66.2 Å²	66.2	29%	0.286	37%	0.372	S	S	.	.	G	3₁₀ helix	trans	-66.5	-24.9	175.1	-20.6	33.6	0	0	0	115.8	K149 I150 Y154 N155 G156 G157	K149-P152 WeakPolarHBondContact O-CD 3.41Å; I150-P152 VanDerWaalsContact C-N 3.31Å; P152-Y154 VanDerWaalsContact C-N 3.31Å; P152-Y154 PolarHBondContact O-N 3.12Å; P152-N155 PolarHBondContact O-N 3.14Å; P152-G156 PolarHBondContact O-N 3.03Å; P152-G157 PolarHBondContact O-N 2.87Å; P152-G157 VanDerWaalsContact O-N 3.13Å
153	F	52.8	Low	66	Low	50 Å²	50	72.8 Å²	72.8	22%	0.219	40%	0.402	C	S	.	.	G	3₁₀ helix	trans	-71.4	-24.4	-176.5	-74.1	-85.2	0	0	0	113.3	I150 V151 N155 V160 I204	I150-F153 PolarHBondContact O-N 3.42Å; V151-F153 PolarHBondContact O-N 3.05Å; F153-N155 VanDerWaalsContact C-N 3.34Å; F153-V160 HydrophobicContact CZ-CG2 4.13Å; F153-I204 HydrophobicContact CZ-CG1 4.24Å
154	Y	49.5	Very low	65.6	Low	115 Å²	115	71.8 Å²	71.8	45%	0.451	40%	0.398	S	S	.	.	G	3₁₀ helix	trans	-78.3	-18.5	174.3	-67.7	-79.2	0	0	0	113.3	I150 P152	I150-Y154 HydrophobicContact CG2-CD2 4.36Å; I150-Y154 HydrophobicContact CG2-CE2 3.72Å; P152-Y154 VanDerWaalsContact C-N 3.31Å; P152-Y154 PolarHBondContact O-N 3.12Å
155	N	42.4	Very low	65.2	Low	137 Å²	137	72.2 Å²	72.2	73%	0.733	39%	0.393	S	S	*	.	T	Hydrogen-bonded Turn	trans	-112.5	11.1	-172.3	-71	-23.6	0	0	0	113.9	P152 F153 G157	P152-N155 PolarHBondContact O-N 3.14Å; F153-N155 VanDerWaalsContact C-N 3.34Å; N155-G157 PolarHBondContact O-N 3.39Å
156	G	45.9	Very low	65.1	Low	73 Å²	73	76.9 Å²	76.9	75%	0.753	41%	0.414	S	S	*	.	T	Hydrogen-bonded Turn	trans	67.6	19.2	-179.7	0	0	0	0	0	114.2	P152 N158	P152-G156 PolarHBondContact O-N 3.03Å; G156-N158 PolarHBondContact O-N 3.42Å
157	G	45.9	Very low	65.3	Low	37 Å²	37	77.8 Å²	77.8	38%	0.381	42%	0.424	S	S	.	.			trans	-81.3	106	179.8	0	0	0	0	0	111.2	P152 N155 C159	P152-G157 PolarHBondContact O-N 2.87Å; P152-G157 VanDerWaalsContact O-N 3.13Å; N155-G157 PolarHBondContact O-N 3.39Å; G157-C159 PolarHBondContact O-N 3.44Å
158	N	53.1	Low	65.6	Low	109 Å²	109	72.2 Å²	72.2	58%	0.583	40%	0.403	S	S	*	.			trans	-87	77.6	177.3	-151.3	31.6	0	0	0	110	G156 Q211	G156-N158 PolarHBondContact O-N 3.42Å; N158-Q211 PolarHBondContact ND2-NE2 3.35Å
159	C	50.7	Low	66.1	Low	90 Å²	90	70.2 Å²	70.2	61%	0.608	39%	0.394	S	S	*	.			trans	-156	89.3	161.4	56.4	0	0	0	0	111.5	G157 T161	G157-C159 PolarHBondContact O-N 3.44Å; C159-T161 PolarHBondContact O-N 3.2Å
160	V	60.3	Low	67.1	Low	31 Å²	31	71.1 Å²	71.1	19%	0.188	40%	0.401	C	S	.	.			trans	-67.7	122.5	149.8	176.6	0	0	0	0	105.8	F153 F164 I204 M208	F153-V160 HydrophobicContact CZ-CG2 4.13Å; V160-F164 HydrophobicContact CG1-CB 3.87Å; V160-F164 HydrophobicContact CG1-CD1 3.32Å; V160-F164 HydrophobicContact CG1-CE1 4.18Å; V160-F164 HydrophobicContact CG1-CG 3.91Å; V160-I204 HydrophobicContact CB-CG2 4.35Å; V160-I204 HydrophobicContact CG1-CG2 4.16Å; V160-I204 HydrophobicContact CG2-CG2 3.6Å; V160-M208 HydrophobicContact CB-SD 4.11Å; V160-M208 HydrophobicContact CG1-SD 4.48Å
161	T	67.9	Low	68.5	Low	46 Å²	46	70.5 Å²	70.5	28%	0.282	40%	0.398	S	S	.	.			trans	-74.9	146.2	178.5	50.8	0	0	0	0	109.4	K149 C159 E163 F164 E165	K149-T161 PolarHBondContact NZ-OG1 3.08Å; C159-T161 PolarHBondContact O-N 3.2Å; T161-E163 PolarHBondContact O-N 2.83Å; T161-F164 WeakPolarHBondContact O-CB 3.34Å; T161-F164 PolarHBondContact O-N 3.39Å; T161-E165 PolarHBondContact O-N 2.95Å
162	D	75.8	Confident	70.3	Confident	119 Å²	119	66.7 Å²	66.7	64%	0.636	38%	0.375	S	S	*	.	H	α-helix	trans	-49.3	-35.2	172.5	-62.8	-18.4	0	0	0	111.2	F164 E165 E166	D162-F164 VanDerWaalsContact C-N 3.29Å; D162-F164 PolarHBondContact O-N 3.45Å; D162-E165 PolarHBondContact O-N 3.19Å; D162-E166 WeakPolarHBondContact O-CG 3.33Å; D162-E166 PolarHBondContact O-N 3.28Å
163	E	81.3	Confident	71.9	Confident	138 Å²	138	68.3 Å²	68.3	65%	0.645	38%	0.38	S	S	*	.	H	α-helix	trans	-56.8	-32.9	173.4	-59.7	175.1	169.7	0	0	114.7	T161 G167	T161-E163 PolarHBondContact O-N 2.83Å; E163-G167 PolarHBondContact O-N 2.99Å
164	F	82.9	Confident	73.7	Confident	8 Å²	8	69.5 Å²	69.5	4%	0.035	38%	0.383	C	S	.	.	H	α-helix	trans	-76.5	-42.2	178.2	172.8	-91	0	0	0	110.9	L145 V146 K149 V160 T161 D162 G167 I168 I204	L145-F164 HydrophobicContact CD1-CD2 4.05Å; L145-F164 HydrophobicContact CD2-CD2 4.02Å; L145-F164 HydrophobicContact CD2-CE2 4.19Å; L145-F164 HydrophobicContact CG-CD2 3.64Å; L145-F164 HydrophobicContact CG-CE2 3.81Å; V146-F164 HydrophobicContact CG2-CE2 4.15Å; V146-F164 HydrophobicContact CG2-CZ 4.14Å; K149-F164 HydrophobicContact CB-CD2 3.87Å; K149-F164 HydrophobicContact CB-CE2 4.03Å; K149-F164 HydrophobicContact CD-CB 4.49Å; K149-F164 HydrophobicContact CD-CD2 4.46Å; K149-F164 HydrophobicContact CG-CD2 3.66Å; K149-F164 HydrophobicContact CG-CE2 4.25Å; K149-F164 HydrophobicContact CG-CG 4.41Å; V160-F164 HydrophobicContact CG1-CB 3.87Å; V160-F164 HydrophobicContact CG1-CD1 3.32Å; V160-F164 HydrophobicContact CG1-CE1 4.18Å; V160-F164 HydrophobicContact CG1-CG 3.91Å; T161-F164 WeakPolarHBondContact O-CB 3.34Å; T161-F164 PolarHBondContact O-N 3.39Å; D162-F164 VanDerWaalsContact C-N 3.29Å; D162-F164 PolarHBondContact O-N 3.45Å; F164-G167 PolarHBondContact O-N 2.99Å; F164-I168 HydrophobicContact CD1-CG1 4.21Å; F164-I168 HydrophobicContact CD2-CG1 4.41Å; F164-I168 HydrophobicContact CE1-CG1 3.71Å; F164-I168 HydrophobicContact CE2-CD1 4.24Å; F164-I168 HydrophobicContact CE2-CG1 3.97Å; F164-I168 HydrophobicContact CZ-CD1 3.99Å; F164-I168 HydrophobicContact CZ-CG1 3.6Å; F164-I168 WeakPolarHBondContact O-CG1 3.31Å; F164-I168 PolarHBondContact O-N 3.32Å; F164-I204 HydrophobicContact CE1-CD1 3.36Å; F164-I204 HydrophobicContact CE1-CG2 4.34Å; F164-I204 HydrophobicContact CZ-CD1 3.49Å; F164-I204 VanDerWaalsContact CZ-CD1 3.49Å
165	E	82.6	Confident	75.7	Confident	64 Å²	64	64 Å²	64	30%	0.299	36%	0.362	S	S	.	.	H	α-helix	trans	-62.6	-46.7	176.6	-174.4	174.8	174.3	0	0	110.2	T161 D162 G167 I168 Q169	T161-E165 PolarHBondContact O-N 2.95Å; D162-E165 PolarHBondContact O-N 3.19Å; E165-G167 VanDerWaalsContact C-N 3.34Å; E165-G167 PolarHBondContact O-N 2.86Å; E165-I168 PolarHBondContact O-N 3.48Å; E165-Q169 WeakPolarHBondContact O-CB 3.21Å; E165-Q169 VanDerWaalsContact O-CG 3.27Å; E165-Q169 WeakPolarHBondContact O-CG 3.36Å; E165-Q169 PolarHBondContact O-N 3.04Å; E165-Q169 PolarHBondContact OE1-NE2 2.96Å
166	E	86.9	Confident	77.8	Confident	132 Å²	132	57.7 Å²	57.7	62%	0.617	33%	0.328	S	S	*	.	H	α-helix	trans	-58.7	-44.1	173.4	-71.3	-179.4	179.5	0	0	111.9	D162 Q169 D170	D162-E166 WeakPolarHBondContact O-CG 3.33Å; D162-E166 PolarHBondContact O-N 3.28Å; E166-Q169 PolarHBondContact O-N 3.17Å; E166-D170 WeakPolarHBondContact O-CB 3.43Å; E166-D170 PolarHBondContact O-N 3.08Å
167	G	90.1	Very high	79.6	Confident	21 Å²	21	57.1 Å²	57.1	22%	0.216	31%	0.306	C	S	.	.	H	α-helix	trans	-61.9	-43.9	177.7	0	0	0	0	0	113.5	E163 F164 E165 D170 I171	E163-G167 PolarHBondContact O-N 2.99Å; F164-G167 PolarHBondContact O-N 2.99Å; E165-G167 VanDerWaalsContact C-N 3.34Å; E165-G167 PolarHBondContact O-N 2.86Å; G167-D170 PolarHBondContact O-N 3.02Å; G167-I171 WeakPolarHBondContact O-CD1 3.37Å; G167-I171 VanDerWaalsContact O-CG1 3.27Å; G167-I171 WeakPolarHBondContact O-CG1 3.49Å; G167-I171 PolarHBondContact O-N 2.72Å
168	I	89.7	Confident	81.6	Confident	2 Å²	2	55.5 Å²	55.5	1%	0.01	29%	0.288	C	S	.	.	H	α-helix	trans	-66.8	-39.8	175.9	-69.9	-68	0	0	0	111.1	L145 V146 F164 E165 I171 I172 I197 Q201	L145-I168 HydrophobicContact CD2-CD1 3.87Å; L145-I168 HydrophobicContact CD2-CG1 3.89Å; V146-I168 HydrophobicContact CG2-CD1 4.3Å; F164-I168 HydrophobicContact CD1-CG1 4.21Å; F164-I168 HydrophobicContact CD2-CG1 4.41Å; F164-I168 HydrophobicContact CE1-CG1 3.71Å; F164-I168 HydrophobicContact CE2-CD1 4.24Å; F164-I168 HydrophobicContact CE2-CG1 3.97Å; F164-I168 HydrophobicContact CZ-CD1 3.99Å; F164-I168 HydrophobicContact CZ-CG1 3.6Å; F164-I168 WeakPolarHBondContact O-CG1 3.31Å; F164-I168 PolarHBondContact O-N 3.32Å; E165-I168 PolarHBondContact O-N 3.48Å; I168-I171 PolarHBondContact O-N 3.4Å; I168-I172 HydrophobicContact CG2-CD1 3.83Å; I168-I172 HydrophobicContact CG2-CG1 4.46Å; I168-I172 VanDerWaalsContact O-CG1 3.3Å; I168-I172 WeakPolarHBondContact O-CG1 3.45Å; I168-I172 PolarHBondContact O-N 2.76Å; I168-I197 HydrophobicContact CD1-CG2 4.45Å; I168-I197 HydrophobicContact CG2-CG2 4.01Å; I168-Q201 HydrophobicContact CG2-CB 4.02Å; I168-Q201 HydrophobicContact CG2-CG 4.2Å
169	Q	88.3	Confident	83.1	Confident	93 Å²	93	53.1 Å²	53.1	44%	0.435	27%	0.273	S	S	.	.	H	α-helix	trans	-63.8	-41.7	176.7	-73.2	179.3	13	0	0	112	E165 E166 I172 L173	E165-Q169 WeakPolarHBondContact O-CB 3.21Å; E165-Q169 VanDerWaalsContact O-CG 3.27Å; E165-Q169 WeakPolarHBondContact O-CG 3.36Å; E165-Q169 PolarHBondContact O-N 3.04Å; E165-Q169 PolarHBondContact OE1-NE2 2.96Å; E166-Q169 PolarHBondContact O-N 3.17Å; Q169-I172 PolarHBondContact O-N 3.48Å; Q169-L173 WeakPolarHBondContact O-CB 3.34Å; Q169-L173 PolarHBondContact O-N 2.89Å
170	D	91.5	Very high	84.7	Confident	75 Å²	75	49 Å²	49	40%	0.401	25%	0.245	S	C	.	.	H	α-helix	trans	-60.5	-46.3	173.6	173.2	75	0	0	0	111.9	E166 G167 I172 L173 R174	E166-D170 WeakPolarHBondContact O-CB 3.43Å; E166-D170 PolarHBondContact O-N 3.08Å; G167-D170 PolarHBondContact O-N 3.02Å; D170-I172 PolarHBondContact O-N 3.29Å; D170-L173 WeakPolarHBondContact O-CB 3.37Å; D170-L173 PolarHBondContact O-N 3.17Å; D170-R174 PolarHBondContact O-N 3.2Å; D170-R174 IonicContact OD1-NE 3.79Å; D170-R174 IonicContact OD2-CZ 2.88Å; D170-R174 IonicContact OD2-NE 2.67Å; D170-R174 PolarHBondContact OD2-NE 2.97Å; D170-R174 IonicContact OD2-NH2 3.21Å; D170-R174 PolarHBondContact OD2-NH2 2.93Å
171	I	94	Very high	85.4	Confident	5 Å²	5	50.1 Å²	50.1	3%	0.026	26%	0.263	C	S	.	.	H	α-helix	trans	-58.3	-47	176.4	-75.5	164.3	0	0	0	111.3	I138 A142 L145 G167 I168 L173 R174 L175 I197	I138-I171 HydrophobicContact CG2-CG2 3.87Å; A142-I171 HydrophobicContact CB-CD1 3.93Å; A142-I171 HydrophobicContact CB-CG2 3.92Å; L145-I171 HydrophobicContact CD2-CD1 3.9Å; G167-I171 WeakPolarHBondContact O-CD1 3.37Å; G167-I171 VanDerWaalsContact O-CG1 3.27Å; G167-I171 WeakPolarHBondContact O-CG1 3.49Å; G167-I171 PolarHBondContact O-N 2.72Å; I168-I171 PolarHBondContact O-N 3.4Å; I171-L173 VanDerWaalsContact C-N 3.31Å; I171-L173 PolarHBondContact O-N 3.06Å; I171-R174 VanDerWaalsContact CG1-NH2 3.33Å; I171-R174 PolarHBondContact O-N 3.01Å; I171-L175 HydrophobicContact CG2-CD1 4.06Å; I171-L175 WeakPolarHBondContact O-CB 3.31Å; I171-L175 PolarHBondContact O-N 3.08Å; I171-I197 HydrophobicContact CG2-CD1 3.7Å; I171-I197 HydrophobicContact CG2-CG2 4.46Å
172	I	90.5	Very high	85.8	Confident	12 Å²	12	49.2 Å²	49.2	6%	0.062	26%	0.263	C	S	.	.	H	α-helix	trans	-59.9	-45.3	177.4	-71.4	165.9	0	0	0	109.9	I168 Q169 D170 L175 T176 L194 I197 P367	I168-I172 HydrophobicContact CG2-CD1 3.83Å; I168-I172 HydrophobicContact CG2-CG1 4.46Å; I168-I172 VanDerWaalsContact O-CG1 3.3Å; I168-I172 WeakPolarHBondContact O-CG1 3.45Å; I168-I172 PolarHBondContact O-N 2.76Å; Q169-I172 PolarHBondContact O-N 3.48Å; D170-I172 PolarHBondContact O-N 3.29Å; I172-L175 PolarHBondContact O-N 3.16Å; I172-T176 WeakPolarHBondContact O-CG2 3.36Å; I172-T176 PolarHBondContact O-N 3.03Å; I172-T176 PolarHBondContact O-OG1 2.96Å; I172-L194 HydrophobicContact CG2-CD2 4.08Å; I172-I197 HydrophobicContact CD1-CG2 4.08Å; I172-I197 HydrophobicContact CG1-CG2 3.71Å; I172-P367 HydrophobicContact CG2-CB 3.92Å; I172-P367 HydrophobicContact CG2-CG 4.19Å
173	L	87.6	Confident	86.1	Confident	78 Å²	78	47.2 Å²	47.2	41%	0.408	25%	0.248	S	C	.	.	H	α-helix	trans	-59.3	-52.6	178.9	-176.5	65	0	0	0	111	Q169 D170 I171 L175 T176 H177	Q169-L173 WeakPolarHBondContact O-CB 3.34Å; Q169-L173 PolarHBondContact O-N 2.89Å; D170-L173 WeakPolarHBondContact O-CB 3.37Å; D170-L173 PolarHBondContact O-N 3.17Å; I171-L173 VanDerWaalsContact C-N 3.31Å; I171-L173 PolarHBondContact O-N 3.06Å; L173-L175 VanDerWaalsContact C-N 3.33Å; L173-L175 PolarHBondContact O-N 3.36Å; L173-T176 PolarHBondContact O-N 3.34Å; L173-T176 VanDerWaalsContact O-N 3.12Å; L173-T176 PolarHBondContact O-OG1 3.42Å; L173-H177 WeakPolarHBondContact CD1-CE1 3.29Å; L173-H177 PolarHBondContact O-N 3.32Å
174	R	91.6	Very high	86.3	Confident	74 Å²	74	43.7 Å²	43.7	28%	0.279	23%	0.234	S	C	.	.	H	α-helix	trans	-58.4	-43.4	178.3	-72.9	-172.6	-69.9	124	-5	112.1	I138 E141 D170 I171 T176 H177 V178	I138-R174 HydrophobicContact CD1-CB 4.31Å; E141-R174 IonicContact OE1-NH1 3.52Å; E141-R174 IonicContact OE2-CZ 3.99Å; E141-R174 IonicContact OE2-NH1 3.9Å; E141-R174 PolarHBondContact OE2-NH1 3.47Å; E141-R174 IonicContact OE2-NH2 3.82Å; E141-R174 PolarHBondContact OE2-NH2 3.11Å; D170-R174 PolarHBondContact O-N 3.2Å; D170-R174 IonicContact OD1-NE 3.79Å; D170-R174 IonicContact OD2-CZ 2.88Å; D170-R174 IonicContact OD2-NE 2.67Å; D170-R174 PolarHBondContact OD2-NE 2.97Å; D170-R174 IonicContact OD2-NH2 3.21Å; D170-R174 PolarHBondContact OD2-NH2 2.93Å; I171-R174 VanDerWaalsContact CG1-NH2 3.33Å; I171-R174 PolarHBondContact O-N 3.01Å; R174-T176 PolarHBondContact O-N 3.3Å; R174-H177 PolarHBondContact O-N 3.36Å; R174-H177 VanDerWaalsContact O-N 3.12Å; R174-V178 PolarHBondContact O-N 2.87Å
175	L	91	Very high	86.6	Confident	0 Å²	0	43.5 Å²	43.5	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-60.5	-41.6	175.6	-83.2	167.2	0	0	0	112.7	I135 I138 I171 I172 L173 H177 V178 R190 T193 L194 I197	I135-L175 HydrophobicContact CB-CD2 4.4Å; I135-L175 HydrophobicContact CG1-CD2 4.38Å; I135-L175 HydrophobicContact CG2-CD2 4.05Å; I138-L175 HydrophobicContact CB-CD2 3.96Å; I138-L175 HydrophobicContact CB-CG 4.11Å; I138-L175 HydrophobicContact CD1-CD2 4.11Å; I138-L175 HydrophobicContact CD1-CG 4.36Å; I138-L175 HydrophobicContact CG2-CD1 4.01Å; I138-L175 HydrophobicContact CG2-CD2 3.99Å; I138-L175 HydrophobicContact CG2-CG 3.55Å; I171-L175 HydrophobicContact CG2-CD1 4.06Å; I171-L175 WeakPolarHBondContact O-CB 3.31Å; I171-L175 PolarHBondContact O-N 3.08Å; I172-L175 PolarHBondContact O-N 3.16Å; L173-L175 VanDerWaalsContact C-N 3.33Å; L173-L175 PolarHBondContact O-N 3.36Å; L175-H177 PolarHBondContact O-N 2.92Å; L175-V178 PolarHBondContact O-N 3.13Å; L175-R190 WeakPolarHBondContact O-CD 3.44Å; L175-R190 WeakPolarHBondContact O-CG 3.22Å; L175-T193 HydrophobicContact CD1-CG2 3.7Å; L175-T193 HydrophobicContact CD2-CG2 4.01Å; L175-L194 HydrophobicContact CB-CD2 3.65Å; L175-L194 HydrophobicContact CB-CG 4.11Å; L175-L194 HydrophobicContact CD1-CD2 4.2Å; L175-I197 HydrophobicContact CD1-CD1 3.3Å
176	T	86	Confident	87	Confident	4 Å²	4	40.5 Å²	40.5	3%	0.025	22%	0.219	C	C	.	.	H	α-helix	trans	-64.7	-22.9	177.5	59.4	0	0	0	0	113.3	I172 L173 R174 L194 P367 W486	I172-T176 WeakPolarHBondContact O-CG2 3.36Å; I172-T176 PolarHBondContact O-N 3.03Å; I172-T176 PolarHBondContact O-OG1 2.96Å; L173-T176 PolarHBondContact O-N 3.34Å; L173-T176 VanDerWaalsContact O-N 3.12Å; L173-T176 PolarHBondContact O-OG1 3.42Å; R174-T176 PolarHBondContact O-N 3.3Å; T176-L194 HydrophobicContact CG2-CD1 3.92Å; T176-L194 HydrophobicContact CG2-CD2 4.03Å; T176-P367 HydrophobicContact CG2-CB 3.72Å; T176-W486 PolarHBondContact O-NE1 2.79Å
177	H	84.6	Confident	86.9	Confident	62 Å²	62	34.8 Å²	34.8	29%	0.287	19%	0.192	S	C	.	.	H	α-helix	trans	-90.5	-10.5	178.1	-65.1	155.8	0	0	0	114.1	L173 R174 L175 K179 E371 R375	L173-H177 WeakPolarHBondContact CD1-CE1 3.29Å; L173-H177 PolarHBondContact O-N 3.32Å; R174-H177 PolarHBondContact O-N 3.36Å; R174-H177 VanDerWaalsContact O-N 3.12Å; L175-H177 PolarHBondContact O-N 2.92Å; H177-K179 PolarHBondContact O-N 2.96Å; H177-E371 IonicContact CD2-OE1 2.65Å; H177-E371 IonicContact NE2-OE1 3.69Å; H177-E371 PolarHBondContact NE2-OE1 3.38Å; H177-R375 PolarHBondContact CD2-NH2 3.32Å; H177-R375 VanDerWaalsContact CD2-NH2 3.34Å
178	V	87.9	Confident	86.7	Confident	2 Å²	2	35.1 Å²	35.1	1%	0.012	19%	0.187	C	C	.	.	S	Bend	trans	-62.3	124.9	175.3	-178.2	0	0	0	0	109.9	H131 E134 I135 I138 R174 L175 R190	H131-V178 HydrophobicContact CB-CG1 3.82Å; E134-V178 HydrophobicContact CG-CG1 4.46Å; E134-V178 HydrophobicContact CG-CG2 4.09Å; I135-V178 HydrophobicContact CD1-CG1 4.13Å; I135-V178 HydrophobicContact CG1-CB 4.14Å; I135-V178 HydrophobicContact CG1-CG1 3.8Å; I135-V178 HydrophobicContact CG1-CG2 4.24Å; I138-V178 HydrophobicContact CD1-CG2 3.62Å; R174-V178 PolarHBondContact O-N 2.87Å; L175-V178 PolarHBondContact O-N 3.13Å; V178-R190 PolarHBondContact O-NH1 3.43Å
179	K	84.6	Confident	86.8	Confident	60 Å²	60	35.1 Å²	35.1	26%	0.261	19%	0.188	S	C	.	.			trans	-71.2	138.2	-177	-65.9	-174.7	172.3	-165.5	0	111.7	H131 H177 D484 E485	H131-K179 WeakPolarHBondContact CB-O 3.4Å; H131-K179 PolarHBondContact CD2-O 3.21Å; H131-K179 VanDerWaalsContact CD2-O 3.29Å; H177-K179 PolarHBondContact O-N 2.96Å; K179-D484 WeakPolarHBondContact CE-OD1 3.28Å; K179-E485 HydrophobicContact CD-CB 4.47Å; K179-E485 IonicContact NZ-OE2 3.31Å; K179-E485 PolarHBondContact NZ-OE2 2.88Å
180	T	82.9	Confident	86.9	Confident	2 Å²	2	30.9 Å²	30.9	1%	0.012	17%	0.168	C	C	.	.			trans	-111.8	-19.6	179.9	60.3	0	0	0	0	113.1	G182 K183 L186 R187	T180-G182 PolarHBondContact O-N 3.37Å; T180-K183 WeakPolarHBondContact O-CB 3.37Å; T180-K183 PolarHBondContact O-N 2.98Å; T180-L186 HydrophobicContact CG2-CB 3.93Å; T180-R187 HydrophobicContact CG2-CG 3.79Å
181	G	76.2	Confident	86.6	Confident	56 Å²	56	29.5 Å²	29.5	58%	0.577	16%	0.157	S	C	*	.	T	Hydrogen-bonded Turn	trans	51.6	39.3	176.8	0	0	0	0	0	113.3	K183 E487	G181-K183 PolarHBondContact O-N 3.39Å; G181-K183 VanDerWaalsContact O-N 3.09Å; G181-E487 WeakPolarHBondContact CA-OE1 3.45Å
182	G	75.2	Confident	86.2	Confident	27 Å²	27	31.5 Å²	31.5	28%	0.278	17%	0.166	S	C	.	.	T	Hydrogen-bonded Turn	trans	73.6	-8	-177	0	0	0	0	0	115.7	T180 I184 E487	T180-G182 PolarHBondContact O-N 3.37Å; G182-I184 PolarHBondContact O-N 3.46Å; G182-E487 WeakPolarHBondContact CA-OE2 3.43Å; G182-E487 PolarHBondContact N-OE1 3.19Å; G182-E487 PolarHBondContact N-OE2 3.37Å
183	K	83.1	Confident	86.2	Confident	76 Å²	76	31.5 Å²	31.5	33%	0.33	17%	0.167	S	C	.	.			trans	-69.3	125	-175.2	-65.4	-172.2	176	179.3	0	111.2	H129 T180 G181 S185 L186 R187	H129-K183 PolarHBondContact CD2-NZ 3.39Å; H129-K183 PolarHBondContact NE2-NZ 3.31Å; T180-K183 WeakPolarHBondContact O-CB 3.37Å; T180-K183 PolarHBondContact O-N 2.98Å; G181-K183 PolarHBondContact O-N 3.39Å; G181-K183 VanDerWaalsContact O-N 3.09Å; K183-S185 VanDerWaalsContact C-N 3.34Å; K183-S185 PolarHBondContact O-N 2.96Å; K183-L186 HydrophobicContact CB-CB 4.27Å; K183-L186 HydrophobicContact CB-CD1 4.12Å; K183-L186 HydrophobicContact CB-CG 4.1Å; K183-L186 HydrophobicContact CD-CD1 4.05Å; K183-L186 HydrophobicContact CD-CG 4.5Å; K183-L186 PolarHBondContact O-N 3.1Å; K183-R187 PolarHBondContact O-N 3.37Å; K183-R187 VanDerWaalsContact O-N 3.08Å
184	I	84.9	Confident	86.2	Confident	65 Å²	65	27.8 Å²	27.8	33%	0.333	15%	0.148	S	C	.	.	H	α-helix	trans	-60.8	-44.7	178.7	-69.3	171.3	0	0	0	110.8	V69 G182 L186 R187 K188 F309	V69-I184 HydrophobicContact CG1-CD1 4.27Å; G182-I184 PolarHBondContact O-N 3.46Å; I184-L186 VanDerWaalsContact C-N 3.34Å; I184-L186 PolarHBondContact O-N 3.4Å; I184-R187 PolarHBondContact O-N 3.09Å; I184-K188 WeakPolarHBondContact O-CB 3.49Å; I184-K188 PolarHBondContact O-N 3.21Å; I184-F309 HydrophobicContact CG2-CE2 3.72Å; I184-F309 HydrophobicContact CG2-CZ 4.02Å
185	S	89.4	Confident	85.9	Confident	3 Å²	3	25.5 Å²	25.5	2%	0.021	14%	0.142	C	C	.	.	H	α-helix	trans	-53.4	-46.6	177	49.1	0	0	0	0	113	F71 S72 N126 K183 A189	F71-S185 WeakPolarHBondContact O-CB 3.48Å; S72-S185 WeakPolarHBondContact CB-O 3.42Å; N126-S185 PolarHBondContact OD1-OG 2.87Å; K183-S185 VanDerWaalsContact C-N 3.34Å; K183-S185 PolarHBondContact O-N 2.96Å; S185-A189 WeakPolarHBondContact O-CB 3.32Å; S185-A189 PolarHBondContact O-N 2.84Å
186	L	90.2	Very high	85.8	Confident	2 Å²	2	26.7 Å²	26.7	1%	0.01	15%	0.147	C	C	.	.	H	α-helix	trans	-72.1	-41.5	-179.9	-64.4	179.8	0	0	0	112.5	H129 H131 R132 T180 K183 I184 K188 A189 R190	H129-L186 HydrophobicContact CB-CD2 4.2Å; H131-L186 HydrophobicContact CB-CD1 4.14Å; H131-L186 HydrophobicContact CB-CD2 4.32Å; R132-L186 HydrophobicContact CB-CD2 3.77Å; T180-L186 HydrophobicContact CG2-CB 3.93Å; K183-L186 HydrophobicContact CB-CB 4.27Å; K183-L186 HydrophobicContact CB-CD1 4.12Å; K183-L186 HydrophobicContact CB-CG 4.1Å; K183-L186 HydrophobicContact CD-CD1 4.05Å; K183-L186 HydrophobicContact CD-CG 4.5Å; K183-L186 PolarHBondContact O-N 3.1Å; I184-L186 VanDerWaalsContact C-N 3.34Å; I184-L186 PolarHBondContact O-N 3.4Å; L186-K188 VanDerWaalsContact C-N 3.33Å; L186-K188 PolarHBondContact O-N 3.3Å; L186-A189 PolarHBondContact O-N 2.99Å; L186-R190 WeakPolarHBondContact O-CB 3.43Å; L186-R190 PolarHBondContact O-N 3.48Å
187	R	86.5	Confident	86	Confident	11 Å²	11	26.5 Å²	26.5	4%	0.042	15%	0.146	C	C	.	.	H	α-helix	trans	-59.9	-45.1	174.6	-72.5	-168.4	-73.3	154.3	3.8	111.3	T180 K183 I184 R190 Y191 D310 Y488	T180-R187 HydrophobicContact CG2-CG 3.79Å; K183-R187 PolarHBondContact O-N 3.37Å; K183-R187 VanDerWaalsContact O-N 3.08Å; I184-R187 PolarHBondContact O-N 3.09Å; R187-R190 PolarHBondContact O-N 3.42Å; R187-Y191 VanDerWaalsContact O-CB 3.27Å; R187-Y191 WeakPolarHBondContact O-CB 3.31Å; R187-Y191 PolarHBondContact O-N 3.45Å; R187-D310 IonicContact CZ-OD1 3.58Å; R187-D310 IonicContact NH1-OD1 2.7Å; R187-D310 PolarHBondContact NH1-OD1 3.43Å; R187-D310 IonicContact NH2-OD1 3.56Å; R187-Y488 WeakPolarHBondContact CD-O 3.46Å; R187-Y488 PolarHBondContact NH1-O 3.02Å; R187-Y488 VanDerWaalsContact NH1-O 3.08Å
188	K	85.9	Confident	86.1	Confident	28 Å²	28	23.8 Å²	23.8	12%	0.122	13%	0.134	C	C	.	.	H	α-helix	trans	-61.2	-47.3	174.9	-174.7	176.7	-179.9	178	0	111.7	I184 L186 R190 Y191 H192 D304 F309	I184-K188 WeakPolarHBondContact O-CB 3.49Å; I184-K188 PolarHBondContact O-N 3.21Å; L186-K188 VanDerWaalsContact C-N 3.33Å; L186-K188 PolarHBondContact O-N 3.3Å; K188-R190 PolarHBondContact O-N 3.16Å; K188-Y191 PolarHBondContact O-N 3.42Å; K188-H192 WeakPolarHBondContact O-CB 3.42Å; K188-H192 PolarHBondContact O-N 3.48Å; K188-D304 WeakPolarHBondContact CE-OD1 3.27Å; K188-D304 IonicContact NZ-OD1 2.73Å; K188-D304 PolarHBondContact NZ-OD1 2.98Å; K188-F309 HydrophobicContact CB-CD1 3.92Å; K188-F309 HydrophobicContact CB-CD2 4.19Å; K188-F309 HydrophobicContact CB-CE1 3.96Å; K188-F309 HydrophobicContact CB-CE2 4.3Å; K188-F309 HydrophobicContact CB-CG 4.02Å; K188-F309 HydrophobicContact CB-CZ 4.14Å; K188-F309 HydrophobicContact CD-CD1 4.22Å; K188-F309 HydrophobicContact CD-CE1 3.68Å; K188-F309 HydrophobicContact CD-CZ 4.19Å; K188-F309 HydrophobicContact CG-CD1 3.75Å; K188-F309 HydrophobicContact CG-CE1 3.72Å; K188-F309 HydrophobicContact CG-CG 4.33Å; K188-F309 HydrophobicContact CG-CZ 4.34Å
189	A	90.4	Very high	86.1	Confident	3 Å²	3	23.9 Å²	23.9	3%	0.025	14%	0.135	C	C	.	.	H	α-helix	trans	-59	-47.9	178.5	0	0	0	0	0	112.3	I135 S185 L186 T193	I135-A189 HydrophobicContact CD1-CB 4.05Å; S185-A189 WeakPolarHBondContact O-CB 3.32Å; S185-A189 PolarHBondContact O-N 2.84Å; L186-A189 PolarHBondContact O-N 2.99Å; A189-T193 WeakPolarHBondContact O-CB 3.48Å; A189-T193 PolarHBondContact O-N 3.07Å; A189-T193 VanDerWaalsContact O-N 3.1Å; A189-T193 PolarHBondContact O-OG1 3.2Å
190	R	90.1	Very high	86.2	Confident	3 Å²	3	21 Å²	21	1%	0.011	12%	0.122	C	C	.	.	H	α-helix	trans	-61.9	-47.9	178.6	-176	175.8	65.7	177	6.2	111	I135 L175 V178 L186 R187 K188 T193 L194 E487 Y488	I135-R190 HydrophobicContact CD1-CB 3.93Å; L175-R190 WeakPolarHBondContact O-CD 3.44Å; L175-R190 WeakPolarHBondContact O-CG 3.22Å; V178-R190 PolarHBondContact O-NH1 3.43Å; L186-R190 WeakPolarHBondContact O-CB 3.43Å; L186-R190 PolarHBondContact O-N 3.48Å; R187-R190 PolarHBondContact O-N 3.42Å; K188-R190 PolarHBondContact O-N 3.16Å; R190-T193 PolarHBondContact O-N 3.4Å; R190-L194 HydrophobicContact CG-CD1 3.93Å; R190-L194 WeakPolarHBondContact O-CB 3.43Å; R190-L194 WeakPolarHBondContact O-CG 3.44Å; R190-L194 PolarHBondContact O-N 3.19Å; R190-E487 PolarHBondContact NH2-O 3.12Å; R190-Y488 PolarHBondContact NH2-OXT 3.15Å
191	Y	85.3	Confident	86.4	Confident	46 Å²	46	22.2 Å²	22.2	18%	0.18	13%	0.128	C	C	.	.	H	α-helix	trans	-61.3	-46.3	179.1	177	-100.2	0	0	0	112.5	R187 K188 T193 L194 T195 A303 A308 F309	R187-Y191 VanDerWaalsContact O-CB 3.27Å; R187-Y191 WeakPolarHBondContact O-CB 3.31Å; R187-Y191 PolarHBondContact O-N 3.45Å; K188-Y191 PolarHBondContact O-N 3.42Å; Y191-T193 VanDerWaalsContact C-N 3.32Å; Y191-T193 PolarHBondContact O-N 3.13Å; Y191-L194 PolarHBondContact O-N 2.76Å; Y191-T195 WeakPolarHBondContact O-CB 3.31Å; Y191-T195 PolarHBondContact O-N 3.3Å; Y191-T195 PolarHBondContact O-OG1 2.72Å; Y191-A303 HydrophobicContact CE1-CB 4.39Å; Y191-A308 HydrophobicContact CD1-CB 4.49Å; Y191-A308 HydrophobicContact CE1-CB 3.6Å; Y191-A308 VanDerWaalsContact CE2-O 3.3Å; Y191-A308 WeakPolarHBondContact CE2-O 3.22Å; Y191-A308 VanDerWaalsContact CZ-O 3.31Å; Y191-F309 HydrophobicContact CD1-CB 3.82Å; Y191-F309 HydrophobicContact CD2-CB 4.49Å; Y191-F309 HydrophobicContact CG-CB 3.73Å
192	H	86.1	Confident	86.9	Confident	47 Å²	47	21.2 Å²	21.2	22%	0.218	11%	0.108	C	C	.	.	H	α-helix	trans	-59.2	-45.4	178.5	-168.1	69.2	0	0	0	111.7	K188 T195 K196 A303	K188-H192 WeakPolarHBondContact O-CB 3.42Å; K188-H192 PolarHBondContact O-N 3.48Å; H192-T195 PolarHBondContact O-N 3Å; H192-K196 VanDerWaalsContact NE2-CE 3.29Å; H192-K196 WeakPolarHBondContact NE2-CE 3.27Å; H192-K196 WeakPolarHBondContact O-CG 3.36Å; H192-K196 PolarHBondContact O-N 3.45Å; H192-K196 VanDerWaalsContact O-N 3.16Å; H192-A303 WeakPolarHBondContact ND1-CB 3.31Å
193	T	90.9	Very high	87.3	Confident	12 Å²	12	20.1 Å²	20.1	7%	0.074	10%	0.096	C	C	.	.	H	α-helix	trans	-64.3	-48.2	179.3	-53.5	0	0	0	0	111.3	I135 F139 L175 A189 R190 Y191 T195 K196 I197	I135-T193 HydrophobicContact CG2-CG2 4.3Å; I135-T193 WeakPolarHBondContact CG2-OG1 3.38Å; F139-T193 HydrophobicContact CB-CG2 3.69Å; F139-T193 HydrophobicContact CD2-CG2 3.54Å; F139-T193 HydrophobicContact CE2-CG2 4.41Å; F139-T193 HydrophobicContact CG-CG2 3.82Å; L175-T193 HydrophobicContact CD1-CG2 3.7Å; L175-T193 HydrophobicContact CD2-CG2 4.01Å; A189-T193 WeakPolarHBondContact O-CB 3.48Å; A189-T193 PolarHBondContact O-N 3.07Å; A189-T193 VanDerWaalsContact O-N 3.1Å; A189-T193 PolarHBondContact O-OG1 3.2Å; R190-T193 PolarHBondContact O-N 3.4Å; Y191-T193 VanDerWaalsContact C-N 3.32Å; Y191-T193 PolarHBondContact O-N 3.13Å; T193-T195 VanDerWaalsContact C-N 3.32Å; T193-T195 PolarHBondContact O-N 3.22Å; T193-K196 PolarHBondContact O-N 2.94Å; T193-I197 HydrophobicContact CG2-CD1 3.98Å; T193-I197 WeakPolarHBondContact O-CG1 3.42Å; T193-I197 PolarHBondContact O-N 3Å
194	L	88.1	Confident	87.2	Confident	1 Å²	1	16.9 Å²	16.9	1%	0.005	8%	0.082	C	C	.	.	H	α-helix	trans	-59.7	-42.3	176.5	-77.7	170.1	0	0	0	112.1	I172 L175 T176 R190 Y191 K196 I197 C198 P367	I172-L194 HydrophobicContact CG2-CD2 4.08Å; L175-L194 HydrophobicContact CB-CD2 3.65Å; L175-L194 HydrophobicContact CB-CG 4.11Å; L175-L194 HydrophobicContact CD1-CD2 4.2Å; T176-L194 HydrophobicContact CG2-CD1 3.92Å; T176-L194 HydrophobicContact CG2-CD2 4.03Å; R190-L194 HydrophobicContact CG-CD1 3.93Å; R190-L194 WeakPolarHBondContact O-CB 3.43Å; R190-L194 WeakPolarHBondContact O-CG 3.44Å; R190-L194 PolarHBondContact O-N 3.19Å; Y191-L194 PolarHBondContact O-N 2.76Å; L194-K196 VanDerWaalsContact C-N 3.32Å; L194-K196 PolarHBondContact O-N 3.43Å; L194-I197 PolarHBondContact O-N 3.47Å; L194-C198 WeakPolarHBondContact O-CB 3.31Å; L194-C198 PolarHBondContact O-N 2.89Å; L194-C198 PolarHBondContact O-SG 3.33Å; L194-C198 VanDerWaalsContact O-SG 3.41Å; L194-P367 HydrophobicContact CB-CG 4.4Å; L194-P367 HydrophobicContact CD1-CB 4.45Å; L194-P367 HydrophobicContact CD2-CB 4.22Å; L194-P367 HydrophobicContact CD2-CG 4.21Å
195	T	85.1	Confident	87	Confident	26 Å²	26	16 Å²	16	16%	0.16	8%	0.076	C	C	.	.	H	α-helix	trans	-59.3	-45.1	179.3	-59.9	0	0	0	0	110.9	Y191 H192 T193 A199 L299	Y191-T195 WeakPolarHBondContact O-CB 3.31Å; Y191-T195 PolarHBondContact O-N 3.3Å; Y191-T195 PolarHBondContact O-OG1 2.72Å; H192-T195 PolarHBondContact O-N 3Å; T193-T195 VanDerWaalsContact C-N 3.32Å; T193-T195 PolarHBondContact O-N 3.22Å; T195-A199 VanDerWaalsContact O-CB 3.31Å; T195-A199 WeakPolarHBondContact O-CB 3.37Å; T195-A199 PolarHBondContact O-N 3.03Å; T195-L299 HydrophobicContact CG2-CD1 4.28Å; T195-L299 HydrophobicContact CG2-CD2 3.96Å; T195-L299 HydrophobicContact CG2-CG 4.5Å
196	K	87.9	Confident	86.4	Confident	25 Å²	25	18 Å²	18	11%	0.109	9%	0.087	C	C	.	.	H	α-helix	trans	-63.2	-48.4	176.9	-72.5	178	165.8	-154.9	0	112.2	F139 H192 T193 L194 A199 V200 L245 E300	F139-K196 HydrophobicContact CE2-CB 4.46Å; F139-K196 HydrophobicContact CZ-CD 4.35Å; H192-K196 VanDerWaalsContact NE2-CE 3.29Å; H192-K196 WeakPolarHBondContact NE2-CE 3.27Å; H192-K196 WeakPolarHBondContact O-CG 3.36Å; H192-K196 PolarHBondContact O-N 3.45Å; H192-K196 VanDerWaalsContact O-N 3.16Å; T193-K196 PolarHBondContact O-N 2.94Å; L194-K196 VanDerWaalsContact C-N 3.32Å; L194-K196 PolarHBondContact O-N 3.43Å; K196-A199 PolarHBondContact O-N 3.26Å; K196-V200 WeakPolarHBondContact O-CG2 3.35Å; K196-V200 PolarHBondContact O-N 2.75Å; K196-L245 WeakPolarHBondContact CD-O 3.37Å; K196-E300 IonicContact NZ-OE1 3.4Å; K196-E300 PolarHBondContact NZ-OE1 3.42Å
197	I	90.2	Very high	85.5	Confident	0 Å²	0	19 Å²	19	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-67.4	-41.5	-177.5	-64	171.6	0	0	0	111.3	F139 A142 I168 I171 I172 L175 T193 L194 V200 Q201	F139-I197 HydrophobicContact CD2-CD1 4.1Å; F139-I197 HydrophobicContact CD2-CG1 4.19Å; F139-I197 HydrophobicContact CE2-CG1 4.3Å; A142-I197 HydrophobicContact CB-CD1 3.85Å; A142-I197 HydrophobicContact CB-CG1 4.2Å; I168-I197 HydrophobicContact CD1-CG2 4.45Å; I168-I197 HydrophobicContact CG2-CG2 4.01Å; I171-I197 HydrophobicContact CG2-CD1 3.7Å; I171-I197 HydrophobicContact CG2-CG2 4.46Å; I172-I197 HydrophobicContact CD1-CG2 4.08Å; I172-I197 HydrophobicContact CG1-CG2 3.71Å; L175-I197 HydrophobicContact CD1-CD1 3.3Å; T193-I197 HydrophobicContact CG2-CD1 3.98Å; T193-I197 WeakPolarHBondContact O-CG1 3.42Å; T193-I197 PolarHBondContact O-N 3Å; L194-I197 PolarHBondContact O-N 3.47Å; I197-V200 WeakPolarHBondContact O-CB 3.46Å; I197-V200 PolarHBondContact O-N 3.06Å; I197-Q201 PolarHBondContact O-N 3.3Å
198	C	87.4	Confident	84.5	Confident	5 Å²	5	22.4 Å²	22.4	3%	0.034	11%	0.111	C	C	.	.	H	α-helix	trans	-66.9	-36.9	176.5	-72.3	0	0	0	0	112.4	L194 V200 Q201 E202 P367	L194-C198 WeakPolarHBondContact O-CB 3.31Å; L194-C198 PolarHBondContact O-N 2.89Å; L194-C198 PolarHBondContact O-SG 3.33Å; L194-C198 VanDerWaalsContact O-SG 3.41Å; C198-V200 VanDerWaalsContact C-N 3.31Å; C198-V200 PolarHBondContact O-N 3.36Å; C198-Q201 PolarHBondContact O-N 3.16Å; C198-E202 WeakPolarHBondContact O-CB 3.44Å; C198-E202 VanDerWaalsContact O-CG 3.3Å; C198-E202 WeakPolarHBondContact O-CG 3.49Å; C198-E202 PolarHBondContact O-N 3.42Å; C198-P367 WeakPolarHBondContact SG-CG 3.44Å
199	A	87	Confident	83.3	Confident	3 Å²	3	28.2 Å²	28.2	3%	0.025	14%	0.137	C	C	.	.	H	α-helix	trans	-59.4	-43.9	171.6	0	0	0	0	0	111.3	T195 K196 E202 I203 L245 Y296 L299	T195-A199 VanDerWaalsContact O-CB 3.31Å; T195-A199 WeakPolarHBondContact O-CB 3.37Å; T195-A199 PolarHBondContact O-N 3.03Å; K196-A199 PolarHBondContact O-N 3.26Å; A199-E202 PolarHBondContact O-N 3.07Å; A199-I203 WeakPolarHBondContact O-CD1 3.37Å; A199-I203 WeakPolarHBondContact O-CG1 3.4Å; A199-I203 PolarHBondContact O-N 3.39Å; A199-L245 HydrophobicContact CB-CD1 3.95Å; A199-Y296 HydrophobicContact CB-CD1 3.62Å; A199-Y296 HydrophobicContact CB-CE1 3.87Å; A199-L299 HydrophobicContact CB-CD1 3.53Å
200	V	88.3	Confident	81.7	Confident	0 Å²	0	34.1 Å²	34.1	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-61.7	-47.3	175.2	170.2	0	0	0	0	111.6	V146 K196 I197 C198 E202 I203 I204 I242 L245 M246	V146-V200 HydrophobicContact CG2-CG1 4.12Å; K196-V200 WeakPolarHBondContact O-CG2 3.35Å; K196-V200 PolarHBondContact O-N 2.75Å; I197-V200 WeakPolarHBondContact O-CB 3.46Å; I197-V200 PolarHBondContact O-N 3.06Å; C198-V200 VanDerWaalsContact C-N 3.31Å; C198-V200 PolarHBondContact O-N 3.36Å; V200-E202 VanDerWaalsContact C-N 3.3Å; V200-E202 PolarHBondContact O-N 3.42Å; V200-I203 PolarHBondContact O-N 3.1Å; V200-I204 HydrophobicContact CG1-CD1 3.69Å; V200-I204 HydrophobicContact CG1-CG1 4.49Å; V200-I204 WeakPolarHBondContact O-CB 3.34Å; V200-I204 VanDerWaalsContact O-CG1 3.24Å; V200-I204 WeakPolarHBondContact O-CG1 3.4Å; V200-I204 PolarHBondContact O-N 3.37Å; V200-I242 HydrophobicContact CG1-CG2 3.83Å; V200-I242 HydrophobicContact CG2-CG2 4.01Å; V200-L245 HydrophobicContact CG2-CB 4.05Å; V200-L245 HydrophobicContact CG2-CD1 4.07Å; V200-M246 HydrophobicContact CG2-CG 3.93Å; V200-M246 HydrophobicContact CG2-SD 3.85Å
201	Q	86.9	Confident	79.9	Confident	28 Å²	28	40.1 Å²	40.1	13%	0.131	19%	0.19	C	C	.	.	H	α-helix	trans	-54.8	-47.8	175.5	-174.6	-174.4	2.4	0	0	111.1	I168 I197 C198 I204 E205	I168-Q201 HydrophobicContact CG2-CB 4.02Å; I168-Q201 HydrophobicContact CG2-CG 4.2Å; I197-Q201 PolarHBondContact O-N 3.3Å; C198-Q201 PolarHBondContact O-N 3.16Å; Q201-I204 PolarHBondContact O-N 3.39Å; Q201-E205 HydrophobicContact CG-CG 4.44Å; Q201-E205 WeakPolarHBondContact CG-OE1 3.33Å; Q201-E205 PolarHBondContact NE2-OE1 2.75Å; Q201-E205 WeakPolarHBondContact O-CG 3.37Å; Q201-E205 PolarHBondContact O-N 2.93Å
202	E	85.1	Confident	78.4	Confident	35 Å²	35	39.4 Å²	39.4	16%	0.164	19%	0.191	C	C	.	.	H	α-helix	trans	-65.1	-43.8	-179.3	-74.5	174	-153.2	0	0	113.2	C198 A199 V200 I204 E205 D206 Y296 K365	C198-E202 WeakPolarHBondContact O-CB 3.44Å; C198-E202 VanDerWaalsContact O-CG 3.3Å; C198-E202 WeakPolarHBondContact O-CG 3.49Å; C198-E202 PolarHBondContact O-N 3.42Å; A199-E202 PolarHBondContact O-N 3.07Å; V200-E202 VanDerWaalsContact C-N 3.3Å; V200-E202 PolarHBondContact O-N 3.42Å; E202-I204 PolarHBondContact O-N 3.4Å; E202-E205 PolarHBondContact O-N 3.42Å; E202-D206 WeakPolarHBondContact O-CB 3.21Å; E202-D206 PolarHBondContact O-N 3.48Å; E202-Y296 WeakPolarHBondContact CB-OH 3.5Å; E202-Y296 PolarHBondContact OE2-OH 3.46Å; E202-K365 WeakPolarHBondContact OE1-CD 3.4Å; E202-K365 IonicContact OE1-NZ 3.01Å; E202-K365 VanDerWaalsContact OE2-CD 3.31Å; E202-K365 WeakPolarHBondContact OE2-CD 3.38Å; E202-K365 IonicContact OE2-NZ 2.77Å; E202-K365 PolarHBondContact OE2-NZ 3.44Å
203	I	84.7	Confident	76.9	Confident	3 Å²	3	40.2 Å²	40.2	2%	0.015	20%	0.202	C	C	.	.	H	α-helix	trans	-57.6	-41.2	176.2	-68.3	161	0	0	0	109.4	A199 V200 C207 R238 L241 I242 L245 Y296	A199-I203 WeakPolarHBondContact O-CD1 3.37Å; A199-I203 WeakPolarHBondContact O-CG1 3.4Å; A199-I203 PolarHBondContact O-N 3.39Å; V200-I203 PolarHBondContact O-N 3.1Å; I203-C207 PolarHBondContact O-N 2.92Å; I203-C207 PolarHBondContact O-SG 2.87Å; I203-R238 HydrophobicContact CG2-CB 4.46Å; I203-R238 HydrophobicContact CG2-CG 4.43Å; I203-L241 HydrophobicContact CD1-CD2 3.61Å; I203-L241 HydrophobicContact CD1-CG 3.98Å; I203-L241 HydrophobicContact CG1-CD2 4.47Å; I203-I242 HydrophobicContact CD1-CG1 4.4Å; I203-I242 HydrophobicContact CG2-CD1 3.94Å; I203-I242 HydrophobicContact CG2-CG1 4.02Å; I203-L245 HydrophobicContact CD1-CD1 3.71Å; I203-Y296 HydrophobicContact CD1-CD2 3.82Å; I203-Y296 HydrophobicContact CD1-CE2 4.23Å; I203-Y296 HydrophobicContact CD1-CG 4.04Å; I203-Y296 HydrophobicContact CG1-CD2 3.63Å; I203-Y296 HydrophobicContact CG1-CE2 3.54Å; I203-Y296 HydrophobicContact CG1-CG 4.27Å
204	I	81.1	Confident	75.4	Confident	8 Å²	8	46.3 Å²	46.3	4%	0.041	23%	0.233	C	C	.	.	H	α-helix	trans	-69.9	-46.9	179.9	-69.8	172.8	0	0	0	111.5	F153 V160 F164 V200 Q201 E202 D206 C207 M208 I242	F153-I204 HydrophobicContact CZ-CG1 4.24Å; V160-I204 HydrophobicContact CB-CG2 4.35Å; V160-I204 HydrophobicContact CG1-CG2 4.16Å; V160-I204 HydrophobicContact CG2-CG2 3.6Å; F164-I204 HydrophobicContact CE1-CD1 3.36Å; F164-I204 HydrophobicContact CE1-CG2 4.34Å; F164-I204 HydrophobicContact CZ-CD1 3.49Å; F164-I204 VanDerWaalsContact CZ-CD1 3.49Å; V200-I204 HydrophobicContact CG1-CD1 3.69Å; V200-I204 HydrophobicContact CG1-CG1 4.49Å; V200-I204 WeakPolarHBondContact O-CB 3.34Å; V200-I204 VanDerWaalsContact O-CG1 3.24Å; V200-I204 WeakPolarHBondContact O-CG1 3.4Å; V200-I204 PolarHBondContact O-N 3.37Å; Q201-I204 PolarHBondContact O-N 3.39Å; E202-I204 PolarHBondContact O-N 3.4Å; I204-D206 VanDerWaalsContact C-N 3.33Å; I204-D206 PolarHBondContact O-N 3.49Å; I204-C207 WeakPolarHBondContact O-CB 3.37Å; I204-C207 PolarHBondContact O-N 3.3Å; I204-C207 VanDerWaalsContact O-N 3.14Å; I204-M208 PolarHBondContact O-N 2.9Å; I204-I242 HydrophobicContact CD1-CD1 4.43Å; I204-I242 HydrophobicContact CG1-CD1 4.02Å
205	E	80.4	Confident	74.4	Confident	46 Å²	46	49.8 Å²	49.8	22%	0.215	26%	0.256	C	S	.	.	H	α-helix	trans	-61.5	-39.8	176.6	-76	-174.7	-148.5	0	0	112.5	Q201 E202 C207 M208 K209	Q201-E205 HydrophobicContact CG-CG 4.44Å; Q201-E205 WeakPolarHBondContact CG-OE1 3.33Å; Q201-E205 PolarHBondContact NE2-OE1 2.75Å; Q201-E205 WeakPolarHBondContact O-CG 3.37Å; Q201-E205 PolarHBondContact O-N 2.93Å; E202-E205 PolarHBondContact O-N 3.42Å; E205-C207 VanDerWaalsContact C-N 3.26Å; E205-C207 PolarHBondContact O-N 3.48Å; E205-M208 PolarHBondContact O-N 2.92Å; E205-M208 VanDerWaalsContact O-N 3.08Å; E205-K209 WeakPolarHBondContact O-CB 3.43Å; E205-K209 PolarHBondContact O-N 3.32Å; E205-K209 IonicContact OE2-NZ 2.75Å; E205-K209 PolarHBondContact OE2-NZ 3.08Å
206	D	77.9	Confident	74	Confident	45 Å²	45	50.7 Å²	50.7	24%	0.241	26%	0.259	C	S	.	.	H	α-helix	trans	-62.4	-35.2	176.1	-98.4	-3.1	0	0	0	111.1	E202 I204 M208 K210 K292	E202-D206 WeakPolarHBondContact O-CB 3.21Å; E202-D206 PolarHBondContact O-N 3.48Å; I204-D206 VanDerWaalsContact C-N 3.33Å; I204-D206 PolarHBondContact O-N 3.49Å; D206-M208 VanDerWaalsContact C-N 3.31Å; D206-M208 PolarHBondContact O-N 2.92Å; D206-K210 WeakPolarHBondContact O-CB 3.23Å; D206-K210 PolarHBondContact O-N 3.37Å; D206-K210 VanDerWaalsContact O-N 3.11Å; D206-K292 IonicContact OD1-NZ 3.76Å; D206-K292 IonicContact OD2-NZ 2.76Å; D206-K292 PolarHBondContact OD2-NZ 3.3Å
207	C	70.6	Confident	73.6	Confident	23 Å²	23	52.9 Å²	52.9	16%	0.155	28%	0.278	C	S	.	.	H	α-helix	trans	-64.2	-36	173	-64.1	0	0	0	0	112.2	I203 I204 E205 R238	I203-C207 PolarHBondContact O-N 2.92Å; I203-C207 PolarHBondContact O-SG 2.87Å; I204-C207 WeakPolarHBondContact O-CB 3.37Å; I204-C207 PolarHBondContact O-N 3.3Å; I204-C207 VanDerWaalsContact O-N 3.14Å; E205-C207 VanDerWaalsContact C-N 3.26Å; E205-C207 PolarHBondContact O-N 3.48Å; C207-R238 VanDerWaalsContact SG-CD 3.53Å
208	M	64.8	Low	73	Confident	84 Å²	84	58.7 Å²	58.7	41%	0.414	31%	0.305	S	S	.	.	H	α-helix	trans	-78.2	-41.2	-178.1	-64.4	176.8	72.1	0	0	112.6	V160 I204 E205 D206	V160-M208 HydrophobicContact CB-SD 4.11Å; V160-M208 HydrophobicContact CG1-SD 4.48Å; I204-M208 PolarHBondContact O-N 2.9Å; E205-M208 PolarHBondContact O-N 2.92Å; E205-M208 VanDerWaalsContact O-N 3.08Å; D206-M208 VanDerWaalsContact C-N 3.31Å; D206-M208 PolarHBondContact O-N 2.92Å
209	K	62	Low	72.4	Confident	150 Å²	150	66 Å²	66	65%	0.652	34%	0.343	S	S	*	.	H	α-helix	trans	-87.7	-21.5	-172.1	-67.8	170.8	-176	164.4	0	113.4	E205	E205-K209 WeakPolarHBondContact O-CB 3.43Å; E205-K209 PolarHBondContact O-N 3.32Å; E205-K209 IonicContact OE2-NZ 2.75Å; E205-K209 PolarHBondContact OE2-NZ 3.08Å
210	K	55.2	Low	71.9	Confident	127 Å²	127	68.1 Å²	68.1	55%	0.552	36%	0.362	S	S	*	.			trans	-127.6	73.3	179.6	-69.4	176.9	173.1	179.8	0	110.1	D206 P212	D206-K210 WeakPolarHBondContact O-CB 3.23Å; D206-K210 PolarHBondContact O-N 3.37Å; D206-K210 VanDerWaalsContact O-N 3.11Å; K210-P212 WeakPolarHBondContact O-CD 3.32Å
211	Q	53.5	Low	71.7	Confident	128 Å²	128	70.4 Å²	70.4	60%	0.598	37%	0.372	S	S	*	.			trans	-61.1	126.2	146.5	-75.2	-163	-12	0	0	105.8	N158	N158-Q211 PolarHBondContact ND2-NE2 3.35Å
212	P	53.2	Low	71.5	Confident	32 Å²	32	74.5 Å²	74.5	21%	0.208	40%	0.401	C	S	.	.			trans	-48.4	153.8	170.4	-27.8	37.5	0	0	0	109.1	K210 L214 M231 Y282	K210-P212 WeakPolarHBondContact O-CD 3.32Å; P212-L214 PolarHBondContact O-N 3.33Å; P212-M231 HydrophobicContact CB-CE 4.27Å; P212-M231 HydrophobicContact CB-SD 4.45Å; P212-M231 HydrophobicContact CG-CE 3.46Å; P212-M231 VanDerWaalsContact CG-CE 3.46Å; P212-M231 HydrophobicContact CG-SD 3.95Å; P212-Y282 HydrophobicContact CB-CE2 4.04Å
213	S	55.7	Low	71.7	Confident	63 Å²	63	73.4 Å²	73.4	44%	0.441	40%	0.397	S	S	.	.	S	Bend	trans	-41.4	118.1	162.7	47.2	0	0	0	0	107.5	E285	S213-E285 PolarHBondContact OG-OE2 3.47Å
214	L	58.6	Low	71.8	Confident	140 Å²	140	73.2 Å²	73.2	73%	0.733	40%	0.396	S	S	*	.			trans	-31.9	135.1	-164.9	-81.1	149.6	0	0	0	111.7	P212 L216	P212-L214 PolarHBondContact O-N 3.33Å; L214-L216 PolarHBondContact O-N 3.09Å
215	P	67.6	Low	72.2	Confident	75 Å²	75	74.7 Å²	74.7	49%	0.487	41%	0.41	S	S	.	.	P	Polyproline II helix	trans	-48.1	120.4	-176.3	19.4	-30.9	0	0	0	108.9
216	L	75.9	Confident	72.7	Confident	44 Å²	44	75.8 Å²	75.8	23%	0.23	41%	0.414	C	S	.	.	P	Polyproline II helix	trans	-58.4	145.2	-177.7	-68	176.3	0	0	0	108	L214 E218 V224 N228 I279 Y282	L214-L216 PolarHBondContact O-N 3.09Å; L216-E218 PolarHBondContact O-N 2.92Å; L216-V224 HydrophobicContact CB-CG1 3.7Å; L216-V224 HydrophobicContact CB-CG2 4.17Å; L216-V224 HydrophobicContact CD1-CG2 4.28Å; L216-V224 WeakPolarHBondContact O-CG1 3.42Å; L216-N228 PolarHBondContact O-ND2 2.87Å; L216-I279 HydrophobicContact CD1-CG1 4.12Å; L216-Y282 HydrophobicContact CD1-CD1 3.95Å; L216-Y282 HydrophobicContact CD1-CG 4.19Å; L216-Y282 HydrophobicContact CG-CD1 4.15Å; L216-Y282 HydrophobicContact CG-CG 4.41Å
217	S	79.8	Confident	73.3	Confident	71 Å²	71	73.7 Å²	73.7	50%	0.497	40%	0.402	S	S	.	.	P	Polyproline II helix	trans	-55.2	133.9	175.9	179.7	0	0	0	0	109.6	D219 A220 V224	S217-D219 PolarHBondContact O-N 3.41Å; S217-D219 VanDerWaalsContact O-N 3.12Å; S217-D219 PolarHBondContact OG-N 3.28Å; S217-A220 WeakPolarHBondContact O-CB 3.39Å; S217-A220 PolarHBondContact O-N 3.2Å; S217-V224 WeakPolarHBondContact O-CG1 3.25Å
218	E	76.8	Confident	74.2	Confident	123 Å²	123	73.8 Å²	73.8	58%	0.575	40%	0.402	S	S	*	.	G	3₁₀ helix	trans	-58.4	-25.5	177.1	-64.6	-172.6	168.5	0	0	111.8	L216 A220 A225	L216-E218 PolarHBondContact O-N 2.92Å; E218-A220 PolarHBondContact O-N 3.4Å; E218-A225 HydrophobicContact CG-CB 4.42Å
219	D	75.6	Confident	75.4	Confident	157 Å²	157	74.7 Å²	74.7	84%	0.84	40%	0.403	S	S	*	.	G	3₁₀ helix	trans	-70.8	-11.1	176.5	-58.9	-39.8	0	0	0	113.6	S217	S217-D219 PolarHBondContact O-N 3.41Å; S217-D219 VanDerWaalsContact O-N 3.12Å; S217-D219 PolarHBondContact OG-N 3.28Å
220	A	76.6	Confident	76.8	Confident	49 Å²	49	67.5 Å²	67.5	41%	0.405	37%	0.372	S	S	.	.	G	3₁₀ helix	trans	-75.1	-35.5	-176.2	0	0	0	0	0	113.2	S217 E218 V224	S217-A220 WeakPolarHBondContact O-CB 3.39Å; S217-A220 PolarHBondContact O-N 3.2Å; E218-A220 PolarHBondContact O-N 3.4Å; A220-V224 HydrophobicContact CB-CG2 4.46Å
221	H	83.1	Confident	78.3	Confident	48 Å²	48	63 Å²	63	22%	0.222	35%	0.353	C	S	.	.			trans	-170.1	147	-179.8	-163.6	-99.6	0	0	0	111.8	S223 V224 D272 I279	H221-S223 PolarHBondContact CE1-OG 2.99Å; H221-S223 VanDerWaalsContact ND1-CB 3.31Å; H221-S223 WeakPolarHBondContact ND1-CB 3.38Å; H221-S223 PolarHBondContact ND1-N 3.04Å; H221-S223 VanDerWaalsContact ND1-N 3.16Å; H221-S223 PolarHBondContact ND1-OG 3.41Å; H221-S223 PolarHBondContact O-N 3.44Å; H221-S223 VanDerWaalsContact O-N 3.13Å; H221-V224 HydrophobicContact CB-CG2 3.98Å; H221-V224 WeakPolarHBondContact O-CB 3.44Å; H221-V224 PolarHBondContact O-N 3.13Å; H221-D272 PolarHBondContact CE1-O 3.18Å; H221-I279 HydrophobicContact CB-CD1 3.32Å
222	P	83.7	Confident	79.9	Confident	113 Å²	113	59.9 Å²	59.9	73%	0.734	35%	0.345	S	S	*	.	H	α-helix	trans	-54.2	-35.8	176.1	-27.4	34.9	0	0	0	114.3	V224	P222-V224 VanDerWaalsContact C-N 3.27Å; P222-V224 PolarHBondContact O-N 2.84Å
223	S	88.1	Confident	81.6	Confident	12 Å²	12	61 Å²	61	8%	0.084	35%	0.347	C	S	.	.	H	α-helix	trans	-66.8	-24.1	177.8	-44.5	0	0	0	0	113.4	H221 K226 I227 D272	H221-S223 PolarHBondContact CE1-OG 2.99Å; H221-S223 VanDerWaalsContact ND1-CB 3.31Å; H221-S223 WeakPolarHBondContact ND1-CB 3.38Å; H221-S223 PolarHBondContact ND1-N 3.04Å; H221-S223 VanDerWaalsContact ND1-N 3.16Å; H221-S223 PolarHBondContact ND1-OG 3.41Å; H221-S223 PolarHBondContact O-N 3.44Å; H221-S223 VanDerWaalsContact O-N 3.13Å; S223-K226 PolarHBondContact O-N 2.81Å; S223-I227 VanDerWaalsContact O-CG1 3.29Å; S223-I227 WeakPolarHBondContact O-CG1 3.41Å; S223-I227 PolarHBondContact O-N 3.34Å; S223-D272 PolarHBondContact OG-O 3.13Å
224	V	88.4	Confident	83.1	Confident	0 Å²	0	58 Å²	58	0%	0	33%	0.326	C	S	.	.	H	α-helix	trans	-67.3	-42.2	-177.7	170.3	0	0	0	0	111.3	L216 S217 A220 H221 P222 K226 I227 N228 I279	L216-V224 HydrophobicContact CB-CG1 3.7Å; L216-V224 HydrophobicContact CB-CG2 4.17Å; L216-V224 HydrophobicContact CD1-CG2 4.28Å; L216-V224 WeakPolarHBondContact O-CG1 3.42Å; S217-V224 WeakPolarHBondContact O-CG1 3.25Å; A220-V224 HydrophobicContact CB-CG2 4.46Å; H221-V224 HydrophobicContact CB-CG2 3.98Å; H221-V224 WeakPolarHBondContact O-CB 3.44Å; H221-V224 PolarHBondContact O-N 3.13Å; P222-V224 VanDerWaalsContact C-N 3.27Å; P222-V224 PolarHBondContact O-N 2.84Å; V224-K226 VanDerWaalsContact C-N 3.26Å; V224-K226 PolarHBondContact O-N 3.13Å; V224-I227 PolarHBondContact O-N 2.95Å; V224-I227 VanDerWaalsContact O-N 3.1Å; V224-N228 WeakPolarHBondContact O-CB 3.32Å; V224-N228 PolarHBondContact O-N 3.44Å; V224-I279 HydrophobicContact CG2-CD1 4.06Å; V224-I279 HydrophobicContact CG2-CG1 4.21Å; V224-I279 HydrophobicContact CG2-CG2 4.22Å
225	A	88.6	Confident	84.4	Confident	39 Å²	39	54.4 Å²	54.4	32%	0.322	31%	0.308	S	S	.	.	H	α-helix	trans	-58	-39.8	176.1	0	0	0	0	0	111.9	E218 F229	E218-A225 HydrophobicContact CG-CB 4.42Å; A225-F229 WeakPolarHBondContact O-CB 3.47Å; A225-F229 PolarHBondContact O-N 3.18Å
226	K	90.9	Very high	85.2	Confident	69 Å²	69	55.4 Å²	55.4	30%	0.3	31%	0.305	S	S	.	.	H	α-helix	trans	-70.1	-38.5	175.9	-174.1	61.9	177.1	178.7	0	112.2	S223 V224 F229 V230 D267 L271	S223-K226 PolarHBondContact O-N 2.81Å; V224-K226 VanDerWaalsContact C-N 3.26Å; V224-K226 PolarHBondContact O-N 3.13Å; K226-F229 HydrophobicContact CD-CD1 4.32Å; K226-F229 PolarHBondContact O-N 3.31Å; K226-V230 WeakPolarHBondContact O-CG2 3.41Å; K226-V230 PolarHBondContact O-N 3.47Å; K226-D267 VanDerWaalsContact CE-OD2 3.3Å; K226-D267 WeakPolarHBondContact CE-OD2 3.49Å; K226-D267 IonicContact NZ-OD2 3.7Å; K226-D267 PolarHBondContact NZ-OD2 2.89Å; K226-L271 HydrophobicContact CB-CD1 4.49Å; K226-L271 HydrophobicContact CB-CD2 4.12Å; K226-L271 HydrophobicContact CG-CD1 4.41Å; K226-L271 HydrophobicContact CG-CD2 4Å
227	I	90.6	Very high	85.8	Confident	0 Å²	0	53.7 Å²	53.7	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-64.3	-44.2	174.9	-62	163	0	0	0	110.6	S223 V224 F229 V230 M231 L268 L271 I279 Y282 R283 V286	S223-I227 VanDerWaalsContact O-CG1 3.29Å; S223-I227 WeakPolarHBondContact O-CG1 3.41Å; S223-I227 PolarHBondContact O-N 3.34Å; V224-I227 PolarHBondContact O-N 2.95Å; V224-I227 VanDerWaalsContact O-N 3.1Å; I227-F229 VanDerWaalsContact C-N 3.34Å; I227-F229 PolarHBondContact O-N 3.26Å; I227-V230 PolarHBondContact O-N 2.85Å; I227-M231 WeakPolarHBondContact O-CB 3.45Å; I227-M231 PolarHBondContact O-N 2.92Å; I227-L268 HydrophobicContact CB-CD2 4.37Å; I227-L268 HydrophobicContact CG1-CD2 3.91Å; I227-L268 HydrophobicContact CG2-CD2 4.4Å; I227-L271 HydrophobicContact CD1-CD1 4.19Å; I227-L271 HydrophobicContact CG1-CD1 3.57Å; I227-I279 HydrophobicContact CD1-CG2 3.78Å; I227-Y282 HydrophobicContact CB-CD1 4.19Å; I227-Y282 HydrophobicContact CB-CE1 3.98Å; I227-Y282 HydrophobicContact CD1-CD1 4.25Å; I227-Y282 HydrophobicContact CG2-CD1 3.53Å; I227-Y282 HydrophobicContact CG2-CE1 3.33Å; I227-Y282 HydrophobicContact CG2-CG 4.27Å; I227-R283 HydrophobicContact CD1-CB 3.98Å; I227-V286 HydrophobicContact CG2-CG2 3.86Å
228	N	88.8	Confident	86.2	Confident	26 Å²	26	51 Å²	51	14%	0.139	28%	0.276	C	S	.	.	H	α-helix	trans	-60.6	-42.9	176.1	-70.7	-10.1	0	0	0	111.4	L216 V224 M231 C232 Y282	L216-N228 PolarHBondContact O-ND2 2.87Å; V224-N228 WeakPolarHBondContact O-CB 3.32Å; V224-N228 PolarHBondContact O-N 3.44Å; N228-M231 PolarHBondContact O-N 2.99Å; N228-C232 PolarHBondContact O-N 3.48Å; N228-C232 VanDerWaalsContact O-N 3.07Å; N228-Y282 WeakPolarHBondContact OD1-CE1 3.43Å; N228-Y282 PolarHBondContact OD1-OH 2.97Å
229	F	90.4	Very high	86.6	Confident	102 Å²	102	45.2 Å²	45.2	45%	0.447	25%	0.249	S	C	.	.	H	α-helix	trans	-58.6	-50.5	173.4	172.1	-93.1	0	0	0	111.6	A225 K226 I227 M231 C232 E233	A225-F229 WeakPolarHBondContact O-CB 3.47Å; A225-F229 PolarHBondContact O-N 3.18Å; K226-F229 HydrophobicContact CD-CD1 4.32Å; K226-F229 PolarHBondContact O-N 3.31Å; I227-F229 VanDerWaalsContact C-N 3.34Å; I227-F229 PolarHBondContact O-N 3.26Å; F229-M231 VanDerWaalsContact C-N 3.31Å; F229-M231 PolarHBondContact O-N 3.42Å; F229-C232 WeakPolarHBondContact O-CB 3.47Å; F229-C232 PolarHBondContact O-N 3.46Å; F229-C232 VanDerWaalsContact O-N 3.12Å; F229-E233 HydrophobicContact CD1-CG 4.31Å; F229-E233 HydrophobicContact CE1-CG 3.74Å; F229-E233 HydrophobicContact CE2-CG 4.24Å; F229-E233 HydrophobicContact CZ-CG 3.7Å; F229-E233 PolarHBondContact O-N 3.06Å; F229-E233 VanDerWaalsContact O-N 3.07Å
230	V	91.9	Very high	87.1	Confident	0 Å²	0	38.3 Å²	38.3	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-59.8	-44.2	178.7	171.9	0	0	0	0	110.4	K226 I227 C232 E233 V234 L264 L268 V286 I290	K226-V230 WeakPolarHBondContact O-CG2 3.41Å; K226-V230 PolarHBondContact O-N 3.47Å; I227-V230 PolarHBondContact O-N 2.85Å; V230-C232 VanDerWaalsContact C-N 3.26Å; V230-C232 PolarHBondContact O-N 3.5Å; V230-E233 CarbonylContact O-C 3.59Å; V230-E233 PolarHBondContact O-N 3.12Å; V230-V234 HydrophobicContact CG1-CG2 4.07Å; V230-V234 VanDerWaalsContact O-CG2 3.27Å; V230-V234 WeakPolarHBondContact O-CG2 3.3Å; V230-V234 PolarHBondContact O-N 3.19Å; V230-L264 HydrophobicContact CG1-CB 3.94Å; V230-L264 HydrophobicContact CG1-CD1 4.42Å; V230-L264 HydrophobicContact CG1-CD2 4.15Å; V230-L264 HydrophobicContact CG1-CG 4.39Å; V230-L264 HydrophobicContact CG2-CD2 4.16Å; V230-L268 HydrophobicContact CB-CD2 4.05Å; V230-L268 HydrophobicContact CB-CG 4.38Å; V230-L268 HydrophobicContact CG1-CD1 3.79Å; V230-L268 HydrophobicContact CG1-CD2 4.15Å; V230-L268 HydrophobicContact CG1-CG 4Å; V230-L268 HydrophobicContact CG2-CD2 4.03Å; V230-L268 HydrophobicContact CG2-CG 4.24Å; V230-V286 HydrophobicContact CG1-CG1 4.04Å; V230-I290 HydrophobicContact CG1-CD1 4.09Å
231	M	87.6	Confident	87.7	Confident	32 Å²	32	36 Å²	36	16%	0.158	19%	0.193	C	C	.	.	H	α-helix	trans	-56.1	-39.6	176.1	-179.4	-179.9	166.6	0	0	112.6	P212 I227 N228 F229 V234 N235 Y282 V286	P212-M231 HydrophobicContact CB-CE 4.27Å; P212-M231 HydrophobicContact CB-SD 4.45Å; P212-M231 HydrophobicContact CG-CE 3.46Å; P212-M231 VanDerWaalsContact CG-CE 3.46Å; P212-M231 HydrophobicContact CG-SD 3.95Å; I227-M231 WeakPolarHBondContact O-CB 3.45Å; I227-M231 PolarHBondContact O-N 2.92Å; N228-M231 PolarHBondContact O-N 2.99Å; F229-M231 VanDerWaalsContact C-N 3.31Å; F229-M231 PolarHBondContact O-N 3.42Å; M231-V234 PolarHBondContact O-N 3.22Å; M231-N235 PolarHBondContact O-N 3.19Å; M231-N235 PolarHBondContact O-ND2 3.02Å; M231-Y282 HydrophobicContact SD-CE2 4.49Å; M231-Y282 PolarHBondContact SD-OH 3.38Å; M231-V286 HydrophobicContact CB-CG2 4.47Å
232	C	85.3	Confident	87.9	Confident	62 Å²	62	33.9 Å²	33.9	42%	0.419	18%	0.183	S	C	.	.	H	α-helix	trans	-64	-43.7	174.1	-172.9	0	0	0	0	112.1	N228 F229 V230 V234 N235 K236	N228-C232 PolarHBondContact O-N 3.48Å; N228-C232 VanDerWaalsContact O-N 3.07Å; F229-C232 WeakPolarHBondContact O-CB 3.47Å; F229-C232 PolarHBondContact O-N 3.46Å; F229-C232 VanDerWaalsContact O-N 3.12Å; V230-C232 VanDerWaalsContact C-N 3.26Å; V230-C232 PolarHBondContact O-N 3.5Å; C232-V234 VanDerWaalsContact C-N 3.34Å; C232-V234 PolarHBondContact O-N 2.87Å; C232-N235 WeakPolarHBondContact O-CB 3.49Å; C232-N235 PolarHBondContact O-N 2.85Å; C232-K236 PolarHBondContact O-N 3.43Å; C232-K236 VanDerWaalsContact O-N 3.13Å
233	E	89.2	Confident	88.1	Confident	56 Å²	56	28.7 Å²	28.7	26%	0.262	15%	0.15	S	C	.	.	H	α-helix	trans	-65.1	-37.1	176	-63.5	-57.5	102.7	0	0	112	F229 V230 N235 K236 A237 L264	F229-E233 HydrophobicContact CD1-CG 4.31Å; F229-E233 HydrophobicContact CE1-CG 3.74Å; F229-E233 HydrophobicContact CE2-CG 4.24Å; F229-E233 HydrophobicContact CZ-CG 3.7Å; F229-E233 PolarHBondContact O-N 3.06Å; F229-E233 VanDerWaalsContact O-N 3.07Å; V230-E233 CarbonylContact O-C 3.59Å; V230-E233 PolarHBondContact O-N 3.12Å; E233-N235 VanDerWaalsContact C-N 3.33Å; E233-N235 PolarHBondContact O-N 3.01Å; E233-K236 PolarHBondContact O-N 3.4Å; E233-K236 WeakPolarHBondContact OE1-CE 3.4Å; E233-K236 IonicContact OE1-NZ 3.68Å; E233-K236 PolarHBondContact OE1-NZ 3.01Å; E233-A237 WeakPolarHBondContact O-CB 3.37Å; E233-A237 PolarHBondContact O-N 3.34Å; E233-L264 HydrophobicContact CB-CD1 3.97Å; E233-L264 HydrophobicContact CB-CD2 4.18Å
234	V	88.4	Confident	88.1	Confident	0 Å²	0	29.3 Å²	29.3	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-63	-40	173.8	180	0	0	0	0	110.9	V230 M231 C232 K236 A237 R238 L264 V286 I290 L293	V230-V234 HydrophobicContact CG1-CG2 4.07Å; V230-V234 VanDerWaalsContact O-CG2 3.27Å; V230-V234 WeakPolarHBondContact O-CG2 3.3Å; V230-V234 PolarHBondContact O-N 3.19Å; M231-V234 PolarHBondContact O-N 3.22Å; C232-V234 VanDerWaalsContact C-N 3.34Å; C232-V234 PolarHBondContact O-N 2.87Å; V234-K236 VanDerWaalsContact C-N 3.35Å; V234-K236 PolarHBondContact O-N 3.32Å; V234-A237 WeakPolarHBondContact O-CB 3.49Å; V234-A237 PolarHBondContact O-N 3.25Å; V234-R238 WeakPolarHBondContact O-CG 3.41Å; V234-R238 PolarHBondContact O-N 3.12Å; V234-L264 HydrophobicContact CG2-CD1 4.03Å; V234-V286 HydrophobicContact CG2-CG1 4.5Å; V234-I290 HydrophobicContact CG1-CG1 4.21Å; V234-I290 HydrophobicContact CG2-CD1 3.78Å; V234-I290 HydrophobicContact CG2-CG1 3.41Å; V234-I290 VanDerWaalsContact CG2-CG1 3.41Å; V234-L293 HydrophobicContact CG1-CD1 3.6Å
235	N	84.4	Confident	88	Confident	64 Å²	64	29.8 Å²	29.8	34%	0.342	15%	0.154	S	C	.	.	H	α-helix	trans	-60.8	-40.7	173.7	-76.8	-31.6	0	0	0	112.8	M231 C232 E233 R238 G239	M231-N235 PolarHBondContact O-N 3.19Å; M231-N235 PolarHBondContact O-ND2 3.02Å; C232-N235 WeakPolarHBondContact O-CB 3.49Å; C232-N235 PolarHBondContact O-N 2.85Å; E233-N235 VanDerWaalsContact C-N 3.33Å; E233-N235 PolarHBondContact O-N 3.01Å; N235-R238 WeakPolarHBondContact O-CB 3.46Å; N235-R238 PolarHBondContact O-N 3.12Å; N235-R238 PolarHBondContact OD1-NH1 2.89Å; N235-G239 PolarHBondContact O-N 3.49Å
236	K	85.3	Confident	88	Confident	97 Å²	97	28 Å²	28	42%	0.422	14%	0.14	S	C	.	.	H	α-helix	trans	-65	-45.7	173.7	-64.7	173	-172.6	166.8	0	111.2	C232 E233 V234 R238 G239 V240	C232-K236 PolarHBondContact O-N 3.43Å; C232-K236 VanDerWaalsContact O-N 3.13Å; E233-K236 PolarHBondContact O-N 3.4Å; E233-K236 WeakPolarHBondContact OE1-CE 3.4Å; E233-K236 IonicContact OE1-NZ 3.68Å; E233-K236 PolarHBondContact OE1-NZ 3.01Å; V234-K236 VanDerWaalsContact C-N 3.35Å; V234-K236 PolarHBondContact O-N 3.32Å; K236-R238 PolarHBondContact O-N 3.48Å; K236-G239 PolarHBondContact O-N 3.33Å; K236-V240 PolarHBondContact O-N 2.88Å; K236-V240 VanDerWaalsContact O-N 3.12Å
237	A	88.6	Confident	87.7	Confident	7 Å²	7	26.8 Å²	26.8	6%	0.058	15%	0.146	C	C	.	.	H	α-helix	trans	-58.7	-32.9	178.3	0	0	0	0	0	112.6	E233 V234 V240 L241 L257 L261	E233-A237 WeakPolarHBondContact O-CB 3.37Å; E233-A237 PolarHBondContact O-N 3.34Å; V234-A237 WeakPolarHBondContact O-CB 3.49Å; V234-A237 PolarHBondContact O-N 3.25Å; A237-V240 PolarHBondContact O-N 3.25Å; A237-L241 WeakPolarHBondContact O-CB 3.17Å; A237-L241 PolarHBondContact O-N 3.45Å; A237-L257 HydrophobicContact CB-CD1 3.82Å; A237-L261 HydrophobicContact CB-CD2 3.75Å
238	R	87.8	Confident	87.3	Confident	16 Å²	16	27.9 Å²	27.9	6%	0.06	15%	0.153	C	C	.	.	H	α-helix	trans	-61.1	-48.1	171.3	-72.4	-179.5	176.8	96.3	-10.7	112.9	I203 C207 V234 N235 K236 V240 L241 I242 D289 L293	I203-R238 HydrophobicContact CG2-CB 4.46Å; I203-R238 HydrophobicContact CG2-CG 4.43Å; C207-R238 VanDerWaalsContact SG-CD 3.53Å; V234-R238 WeakPolarHBondContact O-CG 3.41Å; V234-R238 PolarHBondContact O-N 3.12Å; N235-R238 WeakPolarHBondContact O-CB 3.46Å; N235-R238 PolarHBondContact O-N 3.12Å; N235-R238 PolarHBondContact OD1-NH1 2.89Å; K236-R238 PolarHBondContact O-N 3.48Å; R238-V240 VanDerWaalsContact C-N 3.25Å; R238-V240 PolarHBondContact O-N 3.5Å; R238-L241 WeakPolarHBondContact O-CB 3.48Å; R238-L241 PolarHBondContact O-N 3.39Å; R238-L241 VanDerWaalsContact O-N 3.14Å; R238-I242 WeakPolarHBondContact O-CG1 3.49Å; R238-I242 PolarHBondContact O-N 3.4Å; R238-D289 IonicContact CZ-OD1 2.9Å; R238-D289 IonicContact CZ-OD2 3.42Å; R238-D289 VanDerWaalsContact CZ-OD2 3.29Å; R238-D289 IonicContact NH1-OD2 2.7Å; R238-D289 PolarHBondContact NH1-OD2 2.85Å; R238-D289 IonicContact NH2-OD1 2.9Å; R238-D289 PolarHBondContact NH2-OD1 3.49Å; R238-D289 IonicContact NH2-OD2 3.6Å; R238-D289 PolarHBondContact NH2-OD2 3.31Å; R238-L293 HydrophobicContact CG-CD1 3.55Å; R238-L293 HydrophobicContact CG-CD2 3.74Å; R238-L293 HydrophobicContact CG-CG 4.3Å
239	G	84.6	Confident	86.4	Confident	1 Å²	1	29.6 Å²	29.6	1%	0.01	16%	0.163	C	C	.	.	H	α-helix	trans	-59.7	-40.4	178.2	0	0	0	0	0	111.6	N235 K236 A243	N235-G239 PolarHBondContact O-N 3.49Å; K236-G239 PolarHBondContact O-N 3.33Å; G239-A243 WeakPolarHBondContact O-CB 3.49Å; G239-A243 PolarHBondContact O-N 3.36Å
240	V	86.9	Confident	85.1	Confident	12 Å²	12	32.1 Å²	32.1	7%	0.073	18%	0.18	C	C	.	.	H	α-helix	trans	-63.5	-47.2	172.5	178.1	0	0	0	0	111.3	K236 A237 R238 I242 A243 L244 E252 L257	K236-V240 PolarHBondContact O-N 2.88Å; K236-V240 VanDerWaalsContact O-N 3.12Å; A237-V240 PolarHBondContact O-N 3.25Å; R238-V240 VanDerWaalsContact C-N 3.25Å; R238-V240 PolarHBondContact O-N 3.5Å; V240-I242 PolarHBondContact O-N 3.41Å; V240-A243 CarbonylContact O-C 3.56Å; V240-A243 WeakPolarHBondContact O-CA 3.31Å; V240-A243 WeakPolarHBondContact O-CB 3.37Å; V240-A243 PolarHBondContact O-N 3.38Å; V240-A243 VanDerWaalsContact O-N 3.08Å; V240-L244 HydrophobicContact CG1-CD1 4.06Å; V240-L244 HydrophobicContact CG1-CG 4.27Å; V240-L244 WeakPolarHBondContact O-CG 3.18Å; V240-L244 PolarHBondContact O-N 2.96Å; V240-E252 HydrophobicContact CG1-CB 3.94Å; V240-E252 HydrophobicContact CG1-CG 4.19Å; V240-E252 VanDerWaalsContact CG1-OE2 3.23Å; V240-E252 WeakPolarHBondContact CG1-OE2 3.34Å; V240-L257 HydrophobicContact CB-CD1 4.41Å; V240-L257 HydrophobicContact CB-CD2 4.25Å; V240-L257 HydrophobicContact CG1-CD1 4.23Å; V240-L257 HydrophobicContact CG1-CD2 3.93Å
241	L	88.6	Confident	84.1	Confident	1 Å²	1	36.3 Å²	36.3	1%	0.005	21%	0.21	C	C	.	.	H	α-helix	trans	-58.3	-47.4	179	175.4	61.3	0	0	0	111.8	I203 A237 R238 A243 L244 L245 L257 L293 Y296 L297	I203-L241 HydrophobicContact CD1-CD2 3.61Å; I203-L241 HydrophobicContact CD1-CG 3.98Å; I203-L241 HydrophobicContact CG1-CD2 4.47Å; A237-L241 WeakPolarHBondContact O-CB 3.17Å; A237-L241 PolarHBondContact O-N 3.45Å; R238-L241 WeakPolarHBondContact O-CB 3.48Å; R238-L241 PolarHBondContact O-N 3.39Å; R238-L241 VanDerWaalsContact O-N 3.14Å; L241-A243 VanDerWaalsContact C-N 3.25Å; L241-A243 PolarHBondContact O-N 3.07Å; L241-L244 PolarHBondContact O-N 3.26Å; L241-L245 HydrophobicContact CD1-CD1 4.22Å; L241-L245 HydrophobicContact CD1-CG 4.17Å; L241-L245 HydrophobicContact CG-CD1 4.11Å; L241-L245 HydrophobicContact CG-CG 4.49Å; L241-L245 WeakPolarHBondContact O-CG 3.41Å; L241-L245 PolarHBondContact O-N 3.28Å; L241-L257 HydrophobicContact CB-CD2 3.79Å; L241-L257 HydrophobicContact CD1-CD2 4.41Å; L241-L293 HydrophobicContact CD2-CB 4.05Å; L241-L293 HydrophobicContact CD2-CD2 3.91Å; L241-Y296 HydrophobicContact CD2-CD2 4.32Å; L241-L297 HydrophobicContact CD1-CD2 3.45Å; L241-L297 VanDerWaalsContact CD1-CD2 3.45Å; L241-L297 HydrophobicContact CD1-CG 3.79Å
242	I	88.7	Confident	83.7	Confident	2 Å²	2	37.6 Å²	37.6	1%	0.01	22%	0.216	C	C	.	.	H	α-helix	trans	-58.8	-43.2	175.2	-65.3	169.5	0	0	0	109.5	V146 I150 V200 I203 I204 R238 V240 L244 L245 M246	V146-I242 HydrophobicContact CG1-CG2 3.6Å; I150-I242 HydrophobicContact CD1-CB 4.48Å; I150-I242 HydrophobicContact CD1-CG2 3.81Å; I150-I242 HydrophobicContact CG1-CG2 4.18Å; V200-I242 HydrophobicContact CG1-CG2 3.83Å; V200-I242 HydrophobicContact CG2-CG2 4.01Å; I203-I242 HydrophobicContact CD1-CG1 4.4Å; I203-I242 HydrophobicContact CG2-CD1 3.94Å; I203-I242 HydrophobicContact CG2-CG1 4.02Å; I204-I242 HydrophobicContact CD1-CD1 4.43Å; I204-I242 HydrophobicContact CG1-CD1 4.02Å; R238-I242 WeakPolarHBondContact O-CG1 3.49Å; R238-I242 PolarHBondContact O-N 3.4Å; V240-I242 PolarHBondContact O-N 3.41Å; I242-L244 VanDerWaalsContact C-N 3.34Å; I242-L244 PolarHBondContact O-N 2.93Å; I242-L245 PolarHBondContact O-N 2.88Å; I242-M246 WeakPolarHBondContact O-CB 3.49Å; I242-M246 WeakPolarHBondContact O-CG 3.48Å; I242-M246 PolarHBondContact O-N 3.05Å
243	A	86.8	Confident	83.7	Confident	4 Å²	4	38.6 Å²	38.6	3%	0.033	22%	0.22	C	C	.	.	H	α-helix	trans	-64.3	-37.1	178.7	0	0	0	0	0	113.2	I150 G239 V240 L241 G247 V248 N249	I150-A243 HydrophobicContact CD1-CB 4.44Å; G239-A243 WeakPolarHBondContact O-CB 3.49Å; G239-A243 PolarHBondContact O-N 3.36Å; V240-A243 CarbonylContact O-C 3.56Å; V240-A243 WeakPolarHBondContact O-CA 3.31Å; V240-A243 WeakPolarHBondContact O-CB 3.37Å; V240-A243 PolarHBondContact O-N 3.38Å; V240-A243 VanDerWaalsContact O-N 3.08Å; L241-A243 VanDerWaalsContact C-N 3.25Å; L241-A243 PolarHBondContact O-N 3.07Å; A243-G247 PolarHBondContact O-N 3.25Å; A243-V248 VanDerWaalsContact CA-CG2 3.48Å; A243-V248 HydrophobicContact CB-CG2 3.76Å; A243-V248 WeakPolarHBondContact O-CG2 3.42Å; A243-V248 PolarHBondContact O-N 3.37Å; A243-N249 HydrophobicContact CB-CB 3.92Å
244	L	87.6	Confident	83.6	Confident	26 Å²	26	38 Å²	38	14%	0.136	22%	0.221	C	C	.	.	H	α-helix	trans	-67.7	-48.6	174.8	-72.4	174	0	0	0	111.6	V240 L241 I242 M246 G247 E252 L257 L297	V240-L244 HydrophobicContact CG1-CD1 4.06Å; V240-L244 HydrophobicContact CG1-CG 4.27Å; V240-L244 WeakPolarHBondContact O-CG 3.18Å; V240-L244 PolarHBondContact O-N 2.96Å; L241-L244 PolarHBondContact O-N 3.26Å; I242-L244 VanDerWaalsContact C-N 3.34Å; I242-L244 PolarHBondContact O-N 2.93Å; L244-M246 VanDerWaalsContact C-N 3.25Å; L244-M246 PolarHBondContact O-N 3.45Å; L244-G247 PolarHBondContact O-N 3.17Å; L244-E252 HydrophobicContact CD2-CB 4.5Å; L244-E252 VanDerWaalsContact CD2-O 3.27Å; L244-E252 WeakPolarHBondContact CD2-O 3.35Å; L244-L257 HydrophobicContact CD1-CB 4.24Å; L244-L257 HydrophobicContact CD1-CD2 3.85Å; L244-L297 HydrophobicContact CD1-CD2 4.39Å
245	L	87.3	Confident	83.6	Confident	9 Å²	9	47.8 Å²	47.8	5%	0.047	26%	0.258	C	S	.	.	H	α-helix	trans	-57.5	-41.8	177.9	-73.6	171.9	0	0	0	111.2	K196 A199 V200 I203 L241 I242 G247 L299	K196-L245 WeakPolarHBondContact CD-O 3.37Å; A199-L245 HydrophobicContact CB-CD1 3.95Å; V200-L245 HydrophobicContact CG2-CB 4.05Å; V200-L245 HydrophobicContact CG2-CD1 4.07Å; I203-L245 HydrophobicContact CD1-CD1 3.71Å; L241-L245 HydrophobicContact CD1-CD1 4.22Å; L241-L245 HydrophobicContact CD1-CG 4.17Å; L241-L245 HydrophobicContact CG-CD1 4.11Å; L241-L245 HydrophobicContact CG-CG 4.49Å; L241-L245 WeakPolarHBondContact O-CG 3.41Å; L241-L245 PolarHBondContact O-N 3.28Å; I242-L245 PolarHBondContact O-N 2.88Å; L245-G247 VanDerWaalsContact C-N 3.33Å; L245-L299 HydrophobicContact CD2-CD1 4.13Å
246	M	88.3	Confident	83.9	Confident	2 Å²	2	49.3 Å²	49.3	1%	0.01	26%	0.263	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82.2	-7.2	178.2	-62	-53.9	-68.3	0	0	113.5	F139 A142 Q143 V146 V200 I242 L244 V248	F139-M246 HydrophobicContact CD2-CE 4.18Å; F139-M246 HydrophobicContact CE2-CE 3.68Å; F139-M246 HydrophobicContact CE2-SD 3.94Å; F139-M246 HydrophobicContact CZ-CE 4.3Å; F139-M246 HydrophobicContact CZ-SD 4.45Å; A142-M246 VanDerWaalsContact C-CE 3.45Å; A142-M246 HydrophobicContact CB-CE 3.62Å; Q143-M246 HydrophobicContact CB-CE 4.37Å; Q143-M246 HydrophobicContact CG-CB 4.37Å; Q143-M246 HydrophobicContact CG-CE 3.86Å; Q143-M246 WeakPolarHBondContact CG-O 3.3Å; Q143-M246 PolarHBondContact NE2-O 2.98Å; V146-M246 HydrophobicContact CB-CG 4.31Å; V146-M246 HydrophobicContact CG1-CG 3.95Å; V146-M246 HydrophobicContact CG2-CE 4.28Å; V146-M246 HydrophobicContact CG2-CG 4.26Å; V200-M246 HydrophobicContact CG2-CG 3.93Å; V200-M246 HydrophobicContact CG2-SD 3.85Å; I242-M246 WeakPolarHBondContact O-CB 3.49Å; I242-M246 WeakPolarHBondContact O-CG 3.48Å; I242-M246 PolarHBondContact O-N 3.05Å; L244-M246 VanDerWaalsContact C-N 3.25Å; L244-M246 PolarHBondContact O-N 3.45Å; M246-V248 HydrophobicContact CB-CG1 3.71Å; M246-V248 HydrophobicContact CB-CG2 4.15Å; M246-V248 PolarHBondContact O-N 2.83Å
247	G	85.5	Confident	84.2	Confident	43 Å²	43	44.8 Å²	44.8	44%	0.443	24%	0.244	S	C	.	.	T	Hydrogen-bonded Turn	trans	62	27.3	-177.4	0	0	0	0	0	113.7	A243 L244 L245	A243-G247 PolarHBondContact O-N 3.25Å; L244-G247 PolarHBondContact O-N 3.17Å; L245-G247 VanDerWaalsContact C-N 3.33Å
248	V	80.8	Confident	84.4	Confident	24 Å²	24	46.3 Å²	46.3	15%	0.145	25%	0.254	C	S	.	.			trans	-91.7	-13.8	-174.1	-61.9	0	0	0	0	113.1	Q143 R147 I150 A243 M246	Q143-V248 HydrophobicContact CB-CG1 3.81Å; Q143-V248 HydrophobicContact CG-CG1 3.88Å; R147-V248 HydrophobicContact CG-CB 3.96Å; R147-V248 HydrophobicContact CG-CG1 3.87Å; R147-V248 VanDerWaalsContact NH1-CB 3.32Å; R147-V248 PolarHBondContact NH1-O 3.43Å; I150-V248 HydrophobicContact CD1-CG2 4.36Å; A243-V248 VanDerWaalsContact CA-CG2 3.48Å; A243-V248 HydrophobicContact CB-CG2 3.76Å; A243-V248 WeakPolarHBondContact O-CG2 3.42Å; A243-V248 PolarHBondContact O-N 3.37Å; M246-V248 HydrophobicContact CB-CG1 3.71Å; M246-V248 HydrophobicContact CB-CG2 4.15Å; M246-V248 PolarHBondContact O-N 2.83Å
249	N	70.6	Confident	84.7	Confident	62 Å²	62	49.4 Å²	49.4	33%	0.332	28%	0.277	S	S	.	.			trans	-136.3	137.6	178.6	-171.7	4.7	0	0	0	110.9	A243 S251	A243-N249 HydrophobicContact CB-CB 3.92Å; N249-S251 VanDerWaalsContact CG-OG 3.26Å; N249-S251 PolarHBondContact ND2-OG 3.5Å; N249-S251 PolarHBondContact OD1-N 3.07Å; N249-S251 PolarHBondContact OD1-OG 3.36Å
250	N	62.3	Low	85.1	Confident	154 Å²	154	52 Å²	52	82%	0.824	29%	0.292	S	S	*	.			trans	-110.5	5.7	-174.3	-66.9	-25.6	0	0	0	113.7
251	S	71.8	Confident	85.5	Confident	89 Å²	89	51.5 Å²	51.5	62%	0.622	29%	0.289	S	S	*	.	S	Bend	trans	-79.5	-24.8	-175.5	46.4	0	0	0	0	113.7	N249	N249-S251 VanDerWaalsContact CG-OG 3.26Å; N249-S251 PolarHBondContact ND2-OG 3.5Å; N249-S251 PolarHBondContact OD1-N 3.07Å; N249-S251 PolarHBondContact OD1-OG 3.36Å
252	E	79.5	Confident	85.8	Confident	59 Å²	59	54 Å²	54	28%	0.276	31%	0.307	S	S	.	.			trans	-120.5	165.7	-179	-69.2	-161.2	-152.1	0	0	111.9	V240 L244 H256	V240-E252 HydrophobicContact CG1-CB 3.94Å; V240-E252 HydrophobicContact CG1-CG 4.19Å; V240-E252 VanDerWaalsContact CG1-OE2 3.23Å; V240-E252 WeakPolarHBondContact CG1-OE2 3.34Å; L244-E252 HydrophobicContact CD2-CB 4.5Å; L244-E252 VanDerWaalsContact CD2-O 3.27Å; L244-E252 WeakPolarHBondContact CD2-O 3.35Å; E252-H256 IonicContact OE2-CD2 3.06Å
253	T	85.8	Confident	86.2	Confident	83 Å²	83	55.6 Å²	55.6	51%	0.509	32%	0.324	S	S	.	.			trans	-128.2	154.5	177.1	61.9	0	0	0	0	109.8	R255 H256 L257	T253-R255 PolarHBondContact O-N 3.12Å; T253-R255 VanDerWaalsContact O-N 3.17Å; T253-H256 WeakPolarHBondContact O-CB 3.18Å; T253-H256 PolarHBondContact O-N 3.31Å; T253-H256 WeakPolarHBondContact OG1-CB 3.46Å; T253-H256 PolarHBondContact OG1-N 2.96Å; T253-L257 PolarHBondContact O-N 3.25Å
254	C	86.5	Confident	86.6	Confident	43 Å²	43	56.1 Å²	56.1	29%	0.291	33%	0.326	S	S	.	.	H	α-helix	trans	-54	-37.6	175.7	-60.9	0	0	0	0	112.1	L257 S258 L297	C254-L257 PolarHBondContact O-N 2.98Å; C254-S258 VanDerWaalsContact O-CB 3.25Å; C254-S258 WeakPolarHBondContact O-CB 3.39Å; C254-S258 PolarHBondContact O-N 2.56Å; C254-L297 HydrophobicContact CB-CD2 3.85Å
255	R	87.9	Confident	87	Confident	206 Å²	206	56.1 Å²	56.1	78%	0.777	33%	0.326	S	S	*	.	H	α-helix	trans	-63.1	-45.5	176.3	-163.7	-176.5	-149.5	90.8	2.9	112.1	T253 C259	T253-R255 PolarHBondContact O-N 3.12Å; T253-R255 VanDerWaalsContact O-N 3.17Å; R255-C259 PolarHBondContact O-N 3.23Å; R255-C259 PolarHBondContact O-SG 3.03Å
256	H	90.6	Very high	87.4	Confident	96 Å²	96	58.4 Å²	58.4	44%	0.444	35%	0.346	S	S	.	.	H	α-helix	trans	-62.4	-49.4	177.9	-178.3	61.5	0	0	0	111	E252 T253 S258 C259 V260	E252-H256 IonicContact OE2-CD2 3.06Å; T253-H256 WeakPolarHBondContact O-CB 3.18Å; T253-H256 PolarHBondContact O-N 3.31Å; T253-H256 WeakPolarHBondContact OG1-CB 3.46Å; T253-H256 PolarHBondContact OG1-N 2.96Å; H256-S258 VanDerWaalsContact C-N 3.32Å; H256-S258 PolarHBondContact O-N 3.44Å; H256-C259 WeakPolarHBondContact O-CB 3.31Å; H256-C259 PolarHBondContact O-N 2.73Å; H256-C259 VanDerWaalsContact O-N 3.14Å; H256-V260 WeakPolarHBondContact O-CG2 3.24Å; H256-V260 PolarHBondContact O-N 3.5Å
257	L	91.6	Very high	87.7	Confident	2 Å²	2	61.6 Å²	61.6	1%	0.01	36%	0.363	C	S	.	.	H	α-helix	trans	-62.8	-39.6	-179.5	-168.2	58	0	0	0	112	A237 V240 L241 L244 T253 C254 C259 V260 L261 L297	A237-L257 HydrophobicContact CB-CD1 3.82Å; V240-L257 HydrophobicContact CB-CD1 4.41Å; V240-L257 HydrophobicContact CB-CD2 4.25Å; V240-L257 HydrophobicContact CG1-CD1 4.23Å; V240-L257 HydrophobicContact CG1-CD2 3.93Å; L241-L257 HydrophobicContact CB-CD2 3.79Å; L241-L257 HydrophobicContact CD1-CD2 4.41Å; L244-L257 HydrophobicContact CD1-CB 4.24Å; L244-L257 HydrophobicContact CD1-CD2 3.85Å; T253-L257 PolarHBondContact O-N 3.25Å; C254-L257 PolarHBondContact O-N 2.98Å; L257-C259 PolarHBondContact O-N 2.66Å; L257-V260 PolarHBondContact O-N 3.14Å; L257-L261 HydrophobicContact CG-CD1 4.19Å; L257-L261 HydrophobicContact CG-CG 4.45Å; L257-L261 WeakPolarHBondContact O-CB 2.98Å; L257-L261 VanDerWaalsContact O-CG 3.3Å; L257-L261 WeakPolarHBondContact O-CG 3.46Å; L257-L261 PolarHBondContact O-N 2.98Å; L257-L297 HydrophobicContact CB-CD1 4.1Å; L257-L297 HydrophobicContact CB-CD2 4.45Å; L257-L297 HydrophobicContact CD2-CD1 4.38Å; L257-L297 HydrophobicContact CD2-CD2 4.17Å; L257-L297 HydrophobicContact CG-CD1 4.14Å
258	S	92.9	Very high	88.1	Confident	38 Å²	38	59.5 Å²	59.5	27%	0.266	34%	0.342	S	S	.	.	H	α-helix	trans	-60	-43.4	173.8	179.1	0	0	0	0	112.1	C254 H256 S262	C254-S258 VanDerWaalsContact O-CB 3.25Å; C254-S258 WeakPolarHBondContact O-CB 3.39Å; C254-S258 PolarHBondContact O-N 2.56Å; H256-S258 VanDerWaalsContact C-N 3.32Å; H256-S258 PolarHBondContact O-N 3.44Å; S258-S262 VanDerWaalsContact O-CB 3.3Å; S258-S262 WeakPolarHBondContact O-CB 3.45Å; S258-S262 PolarHBondContact O-N 3.28Å; S258-S262 PolarHBondContact O-OG 2.58Å
259	C	93.7	Very high	88.7	Confident	81 Å²	81	63 Å²	63	55%	0.547	36%	0.36	S	S	.	.	H	α-helix	trans	-63.2	-43.1	174.4	-70.4	0	0	0	0	112.3	R255 H256 L257 S262 G263	R255-C259 PolarHBondContact O-N 3.23Å; R255-C259 PolarHBondContact O-SG 3.03Å; H256-C259 WeakPolarHBondContact O-CB 3.31Å; H256-C259 PolarHBondContact O-N 2.73Å; H256-C259 VanDerWaalsContact O-N 3.14Å; L257-C259 PolarHBondContact O-N 2.66Å; C259-S262 PolarHBondContact O-N 2.88Å; C259-G263 PolarHBondContact O-N 3.23Å
260	V	93.7	Very high	89.8	Confident	56 Å²	56	64.2 Å²	64.2	34%	0.339	38%	0.378	S	S	.	.	H	α-helix	trans	-60.9	-52.1	177.5	171.4	0	0	0	0	110.5	H256 L257 S262 G263 L264	H256-V260 WeakPolarHBondContact O-CG2 3.24Å; H256-V260 PolarHBondContact O-N 3.5Å; L257-V260 PolarHBondContact O-N 3.14Å; V260-S262 VanDerWaalsContact C-N 3.34Å; V260-S262 PolarHBondContact O-N 3.03Å; V260-G263 PolarHBondContact O-N 3.1Å; V260-G263 VanDerWaalsContact O-N 3.14Å; V260-L264 HydrophobicContact CG1-CD1 4.44Å; V260-L264 WeakPolarHBondContact O-CG 3.32Å; V260-L264 PolarHBondContact O-N 3.33Å
261	L	94.8	Very high	91.2	Very high	1 Å²	1	58.3 Å²	58.3	1%	0.005	35%	0.346	C	S	.	.	H	α-helix	trans	-59.9	-42.3	179	-71	175.1	0	0	0	112.1	A237 L257 G263 L264 I265 I290 L293 L294 L297	A237-L261 HydrophobicContact CB-CD2 3.75Å; L257-L261 HydrophobicContact CG-CD1 4.19Å; L257-L261 HydrophobicContact CG-CG 4.45Å; L257-L261 WeakPolarHBondContact O-CB 2.98Å; L257-L261 VanDerWaalsContact O-CG 3.3Å; L257-L261 WeakPolarHBondContact O-CG 3.46Å; L257-L261 PolarHBondContact O-N 2.98Å; L261-G263 VanDerWaalsContact C-N 3.33Å; L261-G263 PolarHBondContact O-N 2.66Å; L261-L264 PolarHBondContact O-N 3.18Å; L261-I265 PolarHBondContact O-N 3.08Å; L261-I265 VanDerWaalsContact O-N 3.09Å; L261-I290 HydrophobicContact CB-CG2 3.77Å; L261-I290 HydrophobicContact CD2-CG2 4.01Å; L261-I290 HydrophobicContact CG-CG2 4.38Å; L261-L293 HydrophobicContact CD1-CB 3.89Å; L261-L293 HydrophobicContact CD2-CD1 4.24Å; L261-L294 HydrophobicContact CB-CD2 3.77Å; L261-L294 HydrophobicContact CB-CG 4.06Å; L261-L294 HydrophobicContact CD1-CD2 3.92Å; L261-L294 HydrophobicContact CD1-CG 4.11Å; L261-L297 HydrophobicContact CD1-CD1 4Å
262	S	95.6	Very high	92	Very high	55 Å²	55	59.4 Å²	59.4	39%	0.385	35%	0.345	S	S	.	.	H	α-helix	trans	-64.4	-37.9	175.9	-58.8	0	0	0	0	112.3	S258 C259 V260 I265 A266	S258-S262 VanDerWaalsContact O-CB 3.3Å; S258-S262 WeakPolarHBondContact O-CB 3.45Å; S258-S262 PolarHBondContact O-N 3.28Å; S258-S262 PolarHBondContact O-OG 2.58Å; C259-S262 PolarHBondContact O-N 2.88Å; V260-S262 VanDerWaalsContact C-N 3.34Å; V260-S262 PolarHBondContact O-N 3.03Å; S262-I265 PolarHBondContact O-N 2.83Å; S262-A266 PolarHBondContact O-N 3.49Å; S262-A266 VanDerWaalsContact O-N 3.11Å
263	G	96.3	Very high	92.3	Very high	35 Å²	35	57 Å²	57	36%	0.361	34%	0.335	S	S	.	.	H	α-helix	trans	-63.2	-40.6	173.4	0	0	0	0	0	112.5	C259 V260 L261 I265 A266 D267	C259-G263 PolarHBondContact O-N 3.23Å; V260-G263 PolarHBondContact O-N 3.1Å; V260-G263 VanDerWaalsContact O-N 3.14Å; L261-G263 VanDerWaalsContact C-N 3.33Å; L261-G263 PolarHBondContact O-N 2.66Å; G263-I265 VanDerWaalsContact C-N 3.34Å; G263-I265 PolarHBondContact O-N 2.92Å; G263-A266 PolarHBondContact O-N 3.35Å; G263-D267 PolarHBondContact O-N 3.38Å
264	L	96.3	Very high	92	Very high	15 Å²	15	58.3 Å²	58.3	8%	0.079	35%	0.346	C	S	.	.	H	α-helix	trans	-63.7	-36.8	175.2	-66.5	175.6	0	0	0	112.4	V230 E233 V234 V260 L261 D267 L268 I290	V230-L264 HydrophobicContact CG1-CB 3.94Å; V230-L264 HydrophobicContact CG1-CD1 4.42Å; V230-L264 HydrophobicContact CG1-CD2 4.15Å; V230-L264 HydrophobicContact CG1-CG 4.39Å; V230-L264 HydrophobicContact CG2-CD2 4.16Å; E233-L264 HydrophobicContact CB-CD1 3.97Å; E233-L264 HydrophobicContact CB-CD2 4.18Å; V234-L264 HydrophobicContact CG2-CD1 4.03Å; V260-L264 HydrophobicContact CG1-CD1 4.44Å; V260-L264 WeakPolarHBondContact O-CG 3.32Å; V260-L264 PolarHBondContact O-N 3.33Å; L261-L264 PolarHBondContact O-N 3.18Å; L264-D267 PolarHBondContact O-N 2.89Å; L264-L268 WeakPolarHBondContact O-CG 2.97Å; L264-L268 PolarHBondContact O-N 3.45Å; L264-L268 VanDerWaalsContact O-N 3.09Å; L264-I290 HydrophobicContact CB-CD1 3.97Å
265	I	95.9	Very high	91.7	Very high	26 Å²	26	60 Å²	60	13%	0.133	37%	0.37	C	S	.	.	H	α-helix	trans	-61.8	-47.6	172.1	-67.9	171.2	0	0	0	110.3	L261 S262 G263 D267 L268 D269 I290 L294	L261-I265 PolarHBondContact O-N 3.08Å; L261-I265 VanDerWaalsContact O-N 3.09Å; S262-I265 PolarHBondContact O-N 2.83Å; G263-I265 VanDerWaalsContact C-N 3.34Å; G263-I265 PolarHBondContact O-N 2.92Å; I265-D267 VanDerWaalsContact C-N 3.31Å; I265-D267 PolarHBondContact O-N 3.31Å; I265-L268 WeakPolarHBondContact O-CB 3.32Å; I265-L268 PolarHBondContact O-N 3.22Å; I265-L268 VanDerWaalsContact O-N 3.08Å; I265-D269 PolarHBondContact O-N 2.86Å; I265-I290 HydrophobicContact CD1-CB 4.26Å; I265-I290 HydrophobicContact CD1-CG2 3.64Å; I265-I290 HydrophobicContact CG1-CB 4.05Å; I265-I290 HydrophobicContact CG1-CD1 4.02Å; I265-I290 HydrophobicContact CG1-CG2 3.63Å; I265-L294 HydrophobicContact CD1-CD1 3.89Å
266	A	95.9	Very high	91.5	Very high	57 Å²	57	56.8 Å²	56.8	47%	0.471	36%	0.358	S	S	.	.	H	α-helix	trans	-60.6	-40.4	179.4	0	0	0	0	0	112.3	S262 G263 L268 D269 A270	S262-A266 PolarHBondContact O-N 3.49Å; S262-A266 VanDerWaalsContact O-N 3.11Å; G263-A266 PolarHBondContact O-N 3.35Å; A266-L268 VanDerWaalsContact C-N 3.32Å; A266-L268 PolarHBondContact O-N 2.85Å; A266-D269 PolarHBondContact O-N 3.04Å; A266-A270 PolarHBondContact O-N 3.24Å
267	D	94.8	Very high	91.3	Very high	68 Å²	68	55.9 Å²	55.9	36%	0.364	36%	0.36	S	S	.	.	H	α-helix	trans	-59.5	-40.8	173.5	-90.1	11.5	0	0	0	112.1	K226 G263 L264 I265	K226-D267 VanDerWaalsContact CE-OD2 3.3Å; K226-D267 WeakPolarHBondContact CE-OD2 3.49Å; K226-D267 IonicContact NZ-OD2 3.7Å; K226-D267 PolarHBondContact NZ-OD2 2.89Å; G263-D267 PolarHBondContact O-N 3.38Å; L264-D267 PolarHBondContact O-N 2.89Å; I265-D267 VanDerWaalsContact C-N 3.31Å; I265-D267 PolarHBondContact O-N 3.31Å
268	L	94.1	Very high	91.1	Very high	0 Å²	0	62.8 Å²	62.8	0%	0	39%	0.392	C	S	.	.	H	α-helix	trans	-70.4	-41.5	176.9	-69.8	171.8	0	0	0	111.9	I227 V230 L264 I265 A266 A270 L271 R283 V286 V287 I290	I227-L268 HydrophobicContact CB-CD2 4.37Å; I227-L268 HydrophobicContact CG1-CD2 3.91Å; I227-L268 HydrophobicContact CG2-CD2 4.4Å; V230-L268 HydrophobicContact CB-CD2 4.05Å; V230-L268 HydrophobicContact CB-CG 4.38Å; V230-L268 HydrophobicContact CG1-CD1 3.79Å; V230-L268 HydrophobicContact CG1-CD2 4.15Å; V230-L268 HydrophobicContact CG1-CG 4Å; V230-L268 HydrophobicContact CG2-CD2 4.03Å; V230-L268 HydrophobicContact CG2-CG 4.24Å; L264-L268 WeakPolarHBondContact O-CG 2.97Å; L264-L268 PolarHBondContact O-N 3.45Å; L264-L268 VanDerWaalsContact O-N 3.09Å; I265-L268 WeakPolarHBondContact O-CB 3.32Å; I265-L268 PolarHBondContact O-N 3.22Å; I265-L268 VanDerWaalsContact O-N 3.08Å; A266-L268 VanDerWaalsContact C-N 3.32Å; A266-L268 PolarHBondContact O-N 2.85Å; L268-A270 VanDerWaalsContact C-N 3.26Å; L268-A270 PolarHBondContact O-N 3.41Å; L268-L271 HydrophobicContact CD2-CD1 4.05Å; L268-L271 VanDerWaalsContact O-CB 3.3Å; L268-L271 WeakPolarHBondContact O-CB 3.4Å; L268-L271 WeakPolarHBondContact O-CG 3.22Å; L268-L271 PolarHBondContact O-N 2.78Å; L268-L271 VanDerWaalsContact O-N 3.12Å; L268-R283 HydrophobicContact CB-CG 4.04Å; L268-R283 HydrophobicContact CD2-CG 4.22Å; L268-R283 VanDerWaalsContact O-CD 3.24Å; L268-R283 WeakPolarHBondContact O-CD 3.41Å; L268-V286 HydrophobicContact CD1-CB 4.23Å; L268-V286 HydrophobicContact CD1-CG1 3.82Å; L268-V287 HydrophobicContact CB-CG2 4.07Å; L268-V287 HydrophobicContact CD1-CG2 3.6Å; L268-V287 HydrophobicContact CG-CG2 4.49Å; L268-I290 HydrophobicContact CD1-CD1 3.83Å
269	D	93.2	Very high	90.9	Very high	97 Å²	97	61.3 Å²	61.3	52%	0.519	38%	0.381	S	S	.	.	H	α-helix	trans	-66.3	-28.8	-179.8	-76.3	-22.9	0	0	0	112.6	I265 A266 L271	I265-D269 PolarHBondContact O-N 2.86Å; A266-D269 PolarHBondContact O-N 3.04Å; D269-L271 PolarHBondContact O-N 2.81Å
270	A	93.4	Very high	90.7	Very high	87 Å²	87	61.3 Å²	61.3	72%	0.719	37%	0.369	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.5	-12.2	174.4	0	0	0	0	0	114	A266 L268 D272	A266-A270 PolarHBondContact O-N 3.24Å; L268-A270 VanDerWaalsContact C-N 3.26Å; L268-A270 PolarHBondContact O-N 3.41Å; A270-D272 PolarHBondContact O-N 3.17Å
271	L	91.6	Very high	90.5	Very high	30 Å²	30	61.5 Å²	61.5	16%	0.157	37%	0.369	C	S	.	.	S	Bend	trans	-73.9	127.3	-179.7	-63.1	175.3	0	0	0	111.7	K226 I227 L268 D269 V273 R283	K226-L271 HydrophobicContact CB-CD1 4.49Å; K226-L271 HydrophobicContact CB-CD2 4.12Å; K226-L271 HydrophobicContact CG-CD1 4.41Å; K226-L271 HydrophobicContact CG-CD2 4Å; I227-L271 HydrophobicContact CD1-CD1 4.19Å; I227-L271 HydrophobicContact CG1-CD1 3.57Å; L268-L271 HydrophobicContact CD2-CD1 4.05Å; L268-L271 VanDerWaalsContact O-CB 3.3Å; L268-L271 WeakPolarHBondContact O-CB 3.4Å; L268-L271 WeakPolarHBondContact O-CG 3.22Å; L268-L271 PolarHBondContact O-N 2.78Å; L268-L271 VanDerWaalsContact O-N 3.12Å; D269-L271 PolarHBondContact O-N 2.81Å; L271-V273 HydrophobicContact CB-CG1 4.16Å; L271-V273 PolarHBondContact O-N 3.21Å; L271-R283 PolarHBondContact O-NH1 2.77Å
272	D	87.6	Confident	90.2	Very high	112 Å²	112	61.5 Å²	61.5	60%	0.599	37%	0.369	S	S	*	.			trans	-74.8	114.7	164.8	-171.1	3	0	0	0	109.8	H221 S223 A270 C274	H221-D272 PolarHBondContact CE1-O 3.18Å; S223-D272 PolarHBondContact OG-O 3.13Å; A270-D272 PolarHBondContact O-N 3.17Å; D272-C274 WeakPolarHBondContact OD1-CB 3.43Å; D272-C274 PolarHBondContact OD1-N 3.36Å
273	V	85.3	Confident	90	Very high	9 Å²	9	61.4 Å²	61.4	6%	0.055	36%	0.36	C	S	.	.			trans	-130.3	19.3	177.9	-61.7	0	0	0	0	111	L271 R276 I279 R280	L271-V273 HydrophobicContact CB-CG1 4.16Å; L271-V273 PolarHBondContact O-N 3.21Å; V273-R276 PolarHBondContact O-N 3.22Å; V273-I279 HydrophobicContact CB-CG2 4.21Å; V273-I279 HydrophobicContact CG1-CG2 3.66Å; V273-R280 HydrophobicContact CG2-CB 4.18Å; V273-R280 HydrophobicContact CG2-CG 4.46Å
274	C	81	Confident	89.8	Confident	110 Å²	110	65.7 Å²	65.7	74%	0.743	37%	0.365	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.1	139.3	-178.8	-78.7	0	0	0	0	111.5	D272 R276	D272-C274 WeakPolarHBondContact OD1-CB 3.43Å; D272-C274 PolarHBondContact OD1-N 3.36Å; C274-R276 VanDerWaalsContact C-N 3.28Å; C274-R276 PolarHBondContact O-N 3.27Å
275	G	79.2	Confident	89.4	Confident	78 Å²	78	68.5 Å²	68.5	80%	0.804	38%	0.378	S	S	*	.	T	Hydrogen-bonded Turn	trans	78.7	-9	177.6	0	0	0	0	0	116.7
276	R	83.8	Confident	89.2	Confident	139 Å²	139	67.4 Å²	67.4	53%	0.525	37%	0.372	S	S	.	.			trans	-115.3	98.2	176.9	-63.7	-166.6	-174.3	-108.6	6.7	112.1	V273 C274 E278 I279 R280	V273-R276 PolarHBondContact O-N 3.22Å; C274-R276 VanDerWaalsContact C-N 3.28Å; C274-R276 PolarHBondContact O-N 3.27Å; R276-E278 VanDerWaalsContact C-N 3.35Å; R276-E278 PolarHBondContact O-N 3.29Å; R276-I279 HydrophobicContact CB-CB 4.3Å; R276-I279 HydrophobicContact CB-CD1 3.96Å; R276-I279 HydrophobicContact CB-CG1 4.1Å; R276-I279 HydrophobicContact CG-CD1 4.38Å; R276-I279 PolarHBondContact O-N 2.76Å; R276-R280 PolarHBondContact O-N 3.45Å; R276-R280 VanDerWaalsContact O-N 3.12Å
277	T	87.7	Confident	89	Confident	77 Å²	77	65.8 Å²	65.8	47%	0.472	36%	0.356	S	S	.	.	H	α-helix	trans	-61.2	-40	-174.9	-63.4	0	0	0	0	113.4	R280 N281	T277-R280 PolarHBondContact O-N 2.94Å; T277-R280 PolarHBondContact OG1-NH2 2.89Å; T277-N281 WeakPolarHBondContact O-CB 3.12Å; T277-N281 PolarHBondContact O-N 3.18Å; T277-N281 PolarHBondContact O-OD1 3.19Å
278	E	87.1	Confident	88.8	Confident	148 Å²	148	67.6 Å²	67.6	69%	0.692	36%	0.363	S	S	*	.	H	α-helix	trans	-61.8	-47.4	-179.9	-65.8	169.3	-176.1	0	0	111.7	R276 R280 N281 Y282	R276-E278 VanDerWaalsContact C-N 3.35Å; R276-E278 PolarHBondContact O-N 3.29Å; E278-R280 PolarHBondContact O-N 3.32Å; E278-N281 PolarHBondContact O-N 2.96Å; E278-Y282 WeakPolarHBondContact O-CB 3.44Å; E278-Y282 PolarHBondContact O-N 3.33Å
279	I	88.2	Confident	88.5	Confident	7 Å²	7	68.6 Å²	68.6	4%	0.036	37%	0.368	C	S	.	.	H	α-helix	trans	-68.2	-37.9	-179.8	-52.9	-179.5	0	0	0	111.2	L216 H221 V224 I227 V273 R276 N281 Y282 R283	L216-I279 HydrophobicContact CD1-CG1 4.12Å; H221-I279 HydrophobicContact CB-CD1 3.32Å; V224-I279 HydrophobicContact CG2-CD1 4.06Å; V224-I279 HydrophobicContact CG2-CG1 4.21Å; V224-I279 HydrophobicContact CG2-CG2 4.22Å; I227-I279 HydrophobicContact CD1-CG2 3.78Å; V273-I279 HydrophobicContact CB-CG2 4.21Å; V273-I279 HydrophobicContact CG1-CG2 3.66Å; R276-I279 HydrophobicContact CB-CB 4.3Å; R276-I279 HydrophobicContact CB-CD1 3.96Å; R276-I279 HydrophobicContact CB-CG1 4.1Å; R276-I279 HydrophobicContact CG-CD1 4.38Å; R276-I279 PolarHBondContact O-N 2.76Å; I279-N281 VanDerWaalsContact C-N 3.33Å; I279-N281 PolarHBondContact O-N 2.81Å; I279-Y282 PolarHBondContact O-N 2.93Å; I279-R283 WeakPolarHBondContact O-CB 3.46Å; I279-R283 PolarHBondContact O-N 2.88Å
280	R	89.2	Confident	88.5	Confident	80 Å²	80	64 Å²	64	30%	0.302	34%	0.343	S	S	.	.	H	α-helix	trans	-63.3	-40.2	174.7	-178.7	179.9	60.3	-113.3	0.4	111.8	V273 R276 T277 E278 R284	V273-R280 HydrophobicContact CG2-CB 4.18Å; V273-R280 HydrophobicContact CG2-CG 4.46Å; R276-R280 PolarHBondContact O-N 3.45Å; R276-R280 VanDerWaalsContact O-N 3.12Å; T277-R280 PolarHBondContact O-N 2.94Å; T277-R280 PolarHBondContact OG1-NH2 2.89Å; E278-R280 PolarHBondContact O-N 3.32Å; R280-R284 WeakPolarHBondContact O-CB 3.42Å; R280-R284 PolarHBondContact O-N 2.92Å
281	N	89.7	Confident	88.4	Confident	60 Å²	60	63.1 Å²	63.1	32%	0.321	33%	0.327	S	S	.	.	H	α-helix	trans	-67.9	-44.3	175.9	-69.2	-9.8	0	0	0	110.5	T277 E278 I279 R283 R284 E285	T277-N281 WeakPolarHBondContact O-CB 3.12Å; T277-N281 PolarHBondContact O-N 3.18Å; T277-N281 PolarHBondContact O-OD1 3.19Å; E278-N281 PolarHBondContact O-N 2.96Å; I279-N281 VanDerWaalsContact C-N 3.33Å; I279-N281 PolarHBondContact O-N 2.81Å; N281-R283 PolarHBondContact O-N 2.9Å; N281-R284 WeakPolarHBondContact O-CA 3.5Å; N281-R284 WeakPolarHBondContact O-CB 3.27Å; N281-R284 PolarHBondContact O-N 3.41Å; N281-E285 WeakPolarHBondContact O-CG 3.17Å; N281-E285 PolarHBondContact O-N 2.91Å
282	Y	89	Confident	88.3	Confident	1 Å²	1	64.1 Å²	64.1	0%	0.004	33%	0.33	C	S	.	.	H	α-helix	trans	-59.3	-46.9	177.1	-175.1	-134.6	0	0	0	112.2	P212 L216 I227 N228 M231 E278 I279 R284 E285 V286	P212-Y282 HydrophobicContact CB-CE2 4.04Å; L216-Y282 HydrophobicContact CD1-CD1 3.95Å; L216-Y282 HydrophobicContact CD1-CG 4.19Å; L216-Y282 HydrophobicContact CG-CD1 4.15Å; L216-Y282 HydrophobicContact CG-CG 4.41Å; I227-Y282 HydrophobicContact CB-CD1 4.19Å; I227-Y282 HydrophobicContact CB-CE1 3.98Å; I227-Y282 HydrophobicContact CD1-CD1 4.25Å; I227-Y282 HydrophobicContact CG2-CD1 3.53Å; I227-Y282 HydrophobicContact CG2-CE1 3.33Å; I227-Y282 HydrophobicContact CG2-CG 4.27Å; N228-Y282 WeakPolarHBondContact OD1-CE1 3.43Å; N228-Y282 PolarHBondContact OD1-OH 2.97Å; M231-Y282 HydrophobicContact SD-CE2 4.49Å; M231-Y282 PolarHBondContact SD-OH 3.38Å; E278-Y282 WeakPolarHBondContact O-CB 3.44Å; E278-Y282 PolarHBondContact O-N 3.33Å; I279-Y282 PolarHBondContact O-N 2.93Å; Y282-R284 VanDerWaalsContact C-N 3.32Å; Y282-R284 PolarHBondContact O-N 3.14Å; Y282-E285 PolarHBondContact O-N 2.65Å; Y282-V286 HydrophobicContact CE2-CG2 4.35Å; Y282-V286 WeakPolarHBondContact O-CG2 3.25Å; Y282-V286 PolarHBondContact O-N 3.33Å
283	R	91.9	Very high	88.4	Confident	53 Å²	53	59 Å²	59	20%	0.2	30%	0.302	C	S	.	.	H	α-helix	trans	-56.7	-45.2	172	-174.4	-168.1	68.4	175.7	8.8	111.8	I227 L268 L271 I279 N281 V286 V287	I227-R283 HydrophobicContact CD1-CB 3.98Å; L268-R283 HydrophobicContact CB-CG 4.04Å; L268-R283 HydrophobicContact CD2-CG 4.22Å; L268-R283 VanDerWaalsContact O-CD 3.24Å; L268-R283 WeakPolarHBondContact O-CD 3.41Å; L271-R283 PolarHBondContact O-NH1 2.77Å; I279-R283 WeakPolarHBondContact O-CB 3.46Å; I279-R283 PolarHBondContact O-N 2.88Å; N281-R283 PolarHBondContact O-N 2.9Å; R283-V286 PolarHBondContact O-N 2.81Å; R283-V287 WeakPolarHBondContact O-CG2 3.41Å; R283-V287 PolarHBondContact O-N 3.11Å
284	R	90.7	Very high	88.6	Confident	125 Å²	125	59.8 Å²	59.8	47%	0.472	31%	0.306	S	S	.	.	H	α-helix	trans	-61.5	-43.5	180	-172.6	-167.2	-55.9	168.4	2.9	111.4	R280 N281 Y282 V286 V287 E288	R280-R284 WeakPolarHBondContact O-CB 3.42Å; R280-R284 PolarHBondContact O-N 2.92Å; N281-R284 WeakPolarHBondContact O-CA 3.5Å; N281-R284 WeakPolarHBondContact O-CB 3.27Å; N281-R284 PolarHBondContact O-N 3.41Å; Y282-R284 VanDerWaalsContact C-N 3.32Å; Y282-R284 PolarHBondContact O-N 3.14Å; R284-V286 VanDerWaalsContact C-N 3.32Å; R284-V286 PolarHBondContact O-N 3.43Å; R284-V287 PolarHBondContact O-N 3.32Å; R284-E288 WeakPolarHBondContact CD-OE1 3.25Å; R284-E288 HydrophobicContact CG-CG 4.39Å; R284-E288 WeakPolarHBondContact CG-OE1 3.42Å; R284-E288 WeakPolarHBondContact O-CB 3.5Å; R284-E288 WeakPolarHBondContact O-CG 3.48Å; R284-E288 PolarHBondContact O-N 3.19Å
285	E	89.2	Confident	88.9	Confident	75 Å²	75	61.6 Å²	61.6	35%	0.35	30%	0.301	S	S	.	.	H	α-helix	trans	-57.5	-45.4	176.4	-73.8	175.8	-168.3	0	0	111.2	S213 N281 Y282 E288 D289	S213-E285 PolarHBondContact OG-OE2 3.47Å; N281-E285 WeakPolarHBondContact O-CG 3.17Å; N281-E285 PolarHBondContact O-N 2.91Å; Y282-E285 PolarHBondContact O-N 2.65Å; E285-E288 PolarHBondContact O-N 3.24Å; E285-D289 VanDerWaalsContact O-CB 3.31Å; E285-D289 WeakPolarHBondContact O-CB 3.48Å; E285-D289 PolarHBondContact O-N 3.48Å
286	V	89.9	Confident	89.3	Confident	2 Å²	2	59 Å²	59	1%	0.012	27%	0.268	C	S	.	.	H	α-helix	trans	-66.5	-38.6	177.2	-177.5	0	0	0	0	111.9	I227 V230 M231 V234 L268 Y282 R283 R284 D289 I290	I227-V286 HydrophobicContact CG2-CG2 3.86Å; V230-V286 HydrophobicContact CG1-CG1 4.04Å; M231-V286 HydrophobicContact CB-CG2 4.47Å; V234-V286 HydrophobicContact CG2-CG1 4.5Å; L268-V286 HydrophobicContact CD1-CB 4.23Å; L268-V286 HydrophobicContact CD1-CG1 3.82Å; Y282-V286 HydrophobicContact CE2-CG2 4.35Å; Y282-V286 WeakPolarHBondContact O-CG2 3.25Å; Y282-V286 PolarHBondContact O-N 3.33Å; R283-V286 PolarHBondContact O-N 2.81Å; R284-V286 VanDerWaalsContact C-N 3.32Å; R284-V286 PolarHBondContact O-N 3.43Å; V286-D289 WeakPolarHBondContact O-CB 3.39Å; V286-D289 PolarHBondContact O-N 2.86Å; V286-I290 HydrophobicContact CG1-CD1 4.3Å; V286-I290 WeakPolarHBondContact O-CG1 3.49Å; V286-I290 PolarHBondContact O-N 3.08Å
287	V	92.8	Very high	89.3	Confident	23 Å²	23	53.1 Å²	53.1	14%	0.139	25%	0.246	C	C	.	.	H	α-helix	trans	-65.9	-42.3	174.8	171.1	0	0	0	0	111.6	L268 R283 R284 D289 I290 N291	L268-V287 HydrophobicContact CB-CG2 4.07Å; L268-V287 HydrophobicContact CD1-CG2 3.6Å; L268-V287 HydrophobicContact CG-CG2 4.49Å; R283-V287 WeakPolarHBondContact O-CG2 3.41Å; R283-V287 PolarHBondContact O-N 3.11Å; R284-V287 PolarHBondContact O-N 3.32Å; V287-D289 VanDerWaalsContact C-N 3.25Å; V287-D289 PolarHBondContact O-N 3.33Å; V287-I290 PolarHBondContact O-N 3.1Å; V287-N291 WeakPolarHBondContact CG1-ND2 2.91Å; V287-N291 WeakPolarHBondContact O-CB 3.49Å; V287-N291 PolarHBondContact O-N 3.49Å; V287-N291 PolarHBondContact O-ND2 3Å
288	E	90.6	Very high	88.7	Confident	106 Å²	106	53.8 Å²	53.8	50%	0.495	25%	0.247	S	C	.	.	H	α-helix	trans	-60.6	-39.6	175.8	-76.6	175.4	-165.6	0	0	111.2	R284 E285 N291 K292	R284-E288 WeakPolarHBondContact CD-OE1 3.25Å; R284-E288 HydrophobicContact CG-CG 4.39Å; R284-E288 WeakPolarHBondContact CG-OE1 3.42Å; R284-E288 WeakPolarHBondContact O-CB 3.5Å; R284-E288 WeakPolarHBondContact O-CG 3.48Å; R284-E288 PolarHBondContact O-N 3.19Å; E285-E288 PolarHBondContact O-N 3.24Å; E288-N291 PolarHBondContact O-N 3.34Å; E288-K292 WeakPolarHBondContact O-CG 3.31Å; E288-K292 PolarHBondContact O-N 2.87Å
289	D	87.9	Confident	87.9	Confident	21 Å²	21	48 Å²	48	11%	0.112	22%	0.221	C	C	.	.	H	α-helix	trans	-64.4	-46.5	176.1	-175	41.3	0	0	0	112.6	R238 E285 V286 V287 N291 K292 L293	R238-D289 IonicContact CZ-OD1 2.9Å; R238-D289 IonicContact CZ-OD2 3.42Å; R238-D289 VanDerWaalsContact CZ-OD2 3.29Å; R238-D289 IonicContact NH1-OD2 2.7Å; R238-D289 PolarHBondContact NH1-OD2 2.85Å; R238-D289 IonicContact NH2-OD1 2.9Å; R238-D289 PolarHBondContact NH2-OD1 3.49Å; R238-D289 IonicContact NH2-OD2 3.6Å; R238-D289 PolarHBondContact NH2-OD2 3.31Å; E285-D289 VanDerWaalsContact O-CB 3.31Å; E285-D289 WeakPolarHBondContact O-CB 3.48Å; E285-D289 PolarHBondContact O-N 3.48Å; V286-D289 WeakPolarHBondContact O-CB 3.39Å; V286-D289 PolarHBondContact O-N 2.86Å; V287-D289 VanDerWaalsContact C-N 3.25Å; V287-D289 PolarHBondContact O-N 3.33Å; D289-N291 VanDerWaalsContact C-N 3.32Å; D289-N291 PolarHBondContact O-N 3.24Å; D289-K292 WeakPolarHBondContact O-CB 3.47Å; D289-K292 PolarHBondContact O-N 2.92Å; D289-K292 VanDerWaalsContact O-N 3.16Å; D289-L293 PolarHBondContact O-N 3.21Å
290	I	92.2	Very high	86.6	Confident	0 Å²	0	52 Å²	52	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-58.6	-44.8	172.9	-64.9	164.5	0	0	0	111.4	V230 V234 L261 L264 I265 L268 V286 V287 K292 L293 L294	V230-I290 HydrophobicContact CG1-CD1 4.09Å; V234-I290 HydrophobicContact CG1-CG1 4.21Å; V234-I290 HydrophobicContact CG2-CD1 3.78Å; V234-I290 HydrophobicContact CG2-CG1 3.41Å; V234-I290 VanDerWaalsContact CG2-CG1 3.41Å; L261-I290 HydrophobicContact CB-CG2 3.77Å; L261-I290 HydrophobicContact CD2-CG2 4.01Å; L261-I290 HydrophobicContact CG-CG2 4.38Å; L264-I290 HydrophobicContact CB-CD1 3.97Å; I265-I290 HydrophobicContact CD1-CB 4.26Å; I265-I290 HydrophobicContact CD1-CG2 3.64Å; I265-I290 HydrophobicContact CG1-CB 4.05Å; I265-I290 HydrophobicContact CG1-CD1 4.02Å; I265-I290 HydrophobicContact CG1-CG2 3.63Å; L268-I290 HydrophobicContact CD1-CD1 3.83Å; V286-I290 HydrophobicContact CG1-CD1 4.3Å; V286-I290 WeakPolarHBondContact O-CG1 3.49Å; V286-I290 PolarHBondContact O-N 3.08Å; V287-I290 PolarHBondContact O-N 3.1Å; I290-K292 PolarHBondContact O-N 2.95Å; I290-L293 PolarHBondContact O-N 3.47Å; I290-L293 VanDerWaalsContact O-N 3.09Å; I290-L294 HydrophobicContact CG2-CD1 4.24Å; I290-L294 HydrophobicContact CG2-CG 4.48Å; I290-L294 PolarHBondContact O-N 2.86Å
291	N	92.1	Very high	85.3	Confident	70 Å²	70	56 Å²	56	37%	0.374	26%	0.262	S	S	.	.	H	α-helix	trans	-62.2	-31	179.2	-79.9	-57.7	0	0	0	112.7	V287 E288 D289 K295	V287-N291 WeakPolarHBondContact CG1-ND2 2.91Å; V287-N291 WeakPolarHBondContact O-CB 3.49Å; V287-N291 PolarHBondContact O-N 3.49Å; V287-N291 PolarHBondContact O-ND2 3Å; E288-N291 PolarHBondContact O-N 3.34Å; D289-N291 VanDerWaalsContact C-N 3.32Å; D289-N291 PolarHBondContact O-N 3.24Å; N291-K295 WeakPolarHBondContact O-CG 3.26Å; N291-K295 PolarHBondContact O-N 2.85Å
292	K	88.9	Confident	83.7	Confident	51 Å²	51	59 Å²	59	22%	0.222	27%	0.273	C	S	.	.	H	α-helix	trans	-67.4	-43.8	172	-69.5	173.4	178.7	-172.9	0	111.8	D206 E288 D289 I290 L294 K295 Y296	D206-K292 IonicContact OD1-NZ 3.76Å; D206-K292 IonicContact OD2-NZ 2.76Å; D206-K292 PolarHBondContact OD2-NZ 3.3Å; E288-K292 WeakPolarHBondContact O-CG 3.31Å; E288-K292 PolarHBondContact O-N 2.87Å; D289-K292 WeakPolarHBondContact O-CB 3.47Å; D289-K292 PolarHBondContact O-N 2.92Å; D289-K292 VanDerWaalsContact O-N 3.16Å; I290-K292 PolarHBondContact O-N 2.95Å; K292-L294 VanDerWaalsContact C-N 3.29Å; K292-L294 PolarHBondContact O-N 2.94Å; K292-K295 WeakPolarHBondContact O-CB 3.33Å; K292-K295 PolarHBondContact O-N 3.36Å; K292-Y296 WeakPolarHBondContact O-CD2 3.29Å; K292-Y296 PolarHBondContact O-N 3.36Å
293	L	89.4	Confident	82.2	Confident	4 Å²	4	59 Å²	59	2%	0.021	27%	0.273	C	S	.	.	H	α-helix	trans	-62	-39.4	178.2	-58.5	-174.3	0	0	0	111.7	V234 R238 L241 L261 D289 I290 K295 Y296 L297	V234-L293 HydrophobicContact CG1-CD1 3.6Å; R238-L293 HydrophobicContact CG-CD1 3.55Å; R238-L293 HydrophobicContact CG-CD2 3.74Å; R238-L293 HydrophobicContact CG-CG 4.3Å; L241-L293 HydrophobicContact CD2-CB 4.05Å; L241-L293 HydrophobicContact CD2-CD2 3.91Å; L261-L293 HydrophobicContact CD1-CB 3.89Å; L261-L293 HydrophobicContact CD2-CD1 4.24Å; D289-L293 PolarHBondContact O-N 3.21Å; I290-L293 PolarHBondContact O-N 3.47Å; I290-L293 VanDerWaalsContact O-N 3.09Å; L293-K295 VanDerWaalsContact C-N 3.32Å; L293-K295 PolarHBondContact O-N 2.95Å; L293-Y296 PolarHBondContact O-N 3.45Å; L293-L297 PolarHBondContact O-N 2.96Å
294	L	90.4	Very high	80.6	Confident	25 Å²	25	61.3 Å²	61.3	13%	0.131	29%	0.29	C	S	.	.	H	α-helix	trans	-58.6	-41.6	174.5	-75.3	171.2	0	0	0	112.2	L261 I265 I290 K292 Y296 L297	L261-L294 HydrophobicContact CB-CD2 3.77Å; L261-L294 HydrophobicContact CB-CG 4.06Å; L261-L294 HydrophobicContact CD1-CD2 3.92Å; L261-L294 HydrophobicContact CD1-CG 4.11Å; I265-L294 HydrophobicContact CD1-CD1 3.89Å; I290-L294 HydrophobicContact CG2-CD1 4.24Å; I290-L294 HydrophobicContact CG2-CG 4.48Å; I290-L294 PolarHBondContact O-N 2.86Å; K292-L294 VanDerWaalsContact C-N 3.29Å; K292-L294 PolarHBondContact O-N 2.94Å; L294-Y296 PolarHBondContact O-N 3.3Å; L294-L297 HydrophobicContact CD2-CD1 4.34Å; L294-L297 WeakPolarHBondContact O-CB 3.3Å; L294-L297 PolarHBondContact O-N 3.19Å
295	K	87.8	Confident	79.3	Confident	148 Å²	148	58.7 Å²	58.7	64%	0.643	29%	0.288	S	S	*	.	H	α-helix	trans	-59.6	-33.4	177.5	-70.1	173.8	-177.6	-177	0	113.4	N291 K292 L293 L297 D298	N291-K295 WeakPolarHBondContact O-CG 3.26Å; N291-K295 PolarHBondContact O-N 2.85Å; K292-K295 WeakPolarHBondContact O-CB 3.33Å; K292-K295 PolarHBondContact O-N 3.36Å; L293-K295 VanDerWaalsContact C-N 3.32Å; L293-K295 PolarHBondContact O-N 2.95Å; K295-L297 VanDerWaalsContact C-N 3.3Å; K295-D298 PolarHBondContact O-N 3.38Å
296	Y	86.3	Confident	77.8	Confident	25 Å²	25	59.4 Å²	59.4	10%	0.098	30%	0.298	C	S	.	.	H	α-helix	trans	-74.4	-20.7	178.6	-67.4	-61.1	0	0	0	113	A199 E202 I203 L241 K292 L293 L294 D298 L299	A199-Y296 HydrophobicContact CB-CD1 3.62Å; A199-Y296 HydrophobicContact CB-CE1 3.87Å; E202-Y296 WeakPolarHBondContact CB-OH 3.5Å; E202-Y296 PolarHBondContact OE2-OH 3.46Å; I203-Y296 HydrophobicContact CD1-CD2 3.82Å; I203-Y296 HydrophobicContact CD1-CE2 4.23Å; I203-Y296 HydrophobicContact CD1-CG 4.04Å; I203-Y296 HydrophobicContact CG1-CD2 3.63Å; I203-Y296 HydrophobicContact CG1-CE2 3.54Å; I203-Y296 HydrophobicContact CG1-CG 4.27Å; L241-Y296 HydrophobicContact CD2-CD2 4.32Å; K292-Y296 WeakPolarHBondContact O-CD2 3.29Å; K292-Y296 PolarHBondContact O-N 3.36Å; L293-Y296 PolarHBondContact O-N 3.45Å; L294-Y296 PolarHBondContact O-N 3.3Å; Y296-D298 VanDerWaalsContact C-N 3.3Å; Y296-L299 HydrophobicContact CD1-CD1 3.85Å; Y296-L299 WeakPolarHBondContact O-CD1 3.34Å; Y296-L299 WeakPolarHBondContact O-CG 3.38Å
297	L	84.3	Confident	76.6	Confident	14 Å²	14	68 Å²	68	7%	0.073	34%	0.335	C	S	.	.	H	α-helix	trans	-73.4	-22.8	175.3	-73.1	172.8	0	0	0	113	L241 L244 C254 L257 L261 L293 L294 K295 L299	L241-L297 HydrophobicContact CD1-CD2 3.45Å; L241-L297 VanDerWaalsContact CD1-CD2 3.45Å; L241-L297 HydrophobicContact CD1-CG 3.79Å; L244-L297 HydrophobicContact CD1-CD2 4.39Å; C254-L297 HydrophobicContact CB-CD2 3.85Å; L257-L297 HydrophobicContact CB-CD1 4.1Å; L257-L297 HydrophobicContact CB-CD2 4.45Å; L257-L297 HydrophobicContact CD2-CD1 4.38Å; L257-L297 HydrophobicContact CD2-CD2 4.17Å; L257-L297 HydrophobicContact CG-CD1 4.14Å; L261-L297 HydrophobicContact CD1-CD1 4Å; L293-L297 PolarHBondContact O-N 2.96Å; L294-L297 HydrophobicContact CD2-CD1 4.34Å; L294-L297 WeakPolarHBondContact O-CB 3.3Å; L294-L297 PolarHBondContact O-N 3.19Å; K295-L297 VanDerWaalsContact C-N 3.3Å; L297-L299 VanDerWaalsContact C-N 3.32Å
298	D	75.2	Confident	75.1	Confident	91 Å²	91	68 Å²	68	49%	0.487	34%	0.337	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.8	-3	-179.6	-61.8	-30.3	0	0	0	113	K295 Y296 E300 E301 E302	K295-D298 PolarHBondContact O-N 3.38Å; Y296-D298 VanDerWaalsContact C-N 3.3Å; D298-E300 VanDerWaalsContact C-N 3.28Å; D298-E300 PolarHBondContact O-N 3.44Å; D298-E301 PolarHBondContact O-N 2.93Å; D298-E302 PolarHBondContact O-N 2.68Å
299	L	70.6	Confident	74	Confident	27 Å²	27	63.3 Å²	63.3	14%	0.141	32%	0.315	C	S	.	.	H	α-helix	trans	-62.3	-28.6	-174.9	-71.9	177.3	0	0	0	114.4	T195 A199 L245 Y296 L297 A303	T195-L299 HydrophobicContact CG2-CD1 4.28Å; T195-L299 HydrophobicContact CG2-CD2 3.96Å; T195-L299 HydrophobicContact CG2-CG 4.5Å; A199-L299 HydrophobicContact CB-CD1 3.53Å; L245-L299 HydrophobicContact CD2-CD1 4.13Å; Y296-L299 HydrophobicContact CD1-CD1 3.85Å; Y296-L299 WeakPolarHBondContact O-CD1 3.34Å; Y296-L299 WeakPolarHBondContact O-CG 3.38Å; L297-L299 VanDerWaalsContact C-N 3.32Å; L299-A303 WeakPolarHBondContact O-CB 3.41Å; L299-A303 PolarHBondContact O-N 3.12Å; L299-A303 VanDerWaalsContact O-N 3.15Å
300	E	61.1	Low	73.1	Confident	92 Å²	92	64.2 Å²	64.2	43%	0.43	32%	0.32	S	S	.	.	H	α-helix	trans	-71.6	-33.3	-179.7	-70.5	-161.5	148.1	0	0	112.7	K196 D298	K196-E300 IonicContact NZ-OE1 3.4Å; K196-E300 PolarHBondContact NZ-OE1 3.42Å; D298-E300 VanDerWaalsContact C-N 3.28Å; D298-E300 PolarHBondContact O-N 3.44Å
301	E	60.7	Low	72.2	Confident	164 Å²	164	64.4 Å²	64.4	77%	0.766	32%	0.321	S	S	*	.	H	α-helix	trans	-75.4	-34.5	176.8	-68.9	-168.3	171.2	0	0	111.8	D298	D298-E301 PolarHBondContact O-N 2.93Å
302	E	57.2	Low	71.1	Confident	121 Å²	121	68.1 Å²	68.1	57%	0.565	33%	0.33	S	S	*	.	H	α-helix	trans	-70.6	-40.1	178.4	-69.1	-171.4	164.1	0	0	112.7	D298 D304 T305	D298-E302 PolarHBondContact O-N 2.68Å; E302-D304 PolarHBondContact O-N 3.46Å; E302-T305 PolarHBondContact O-N 3.43Å; E302-T305 PolarHBondContact O-OG1 3.23Å
303	A	56.8	Low	70.3	Confident	1 Å²	1	73 Å²	73	1%	0.008	35%	0.354	C	S	.	.	H	α-helix	trans	-68.7	-19.4	-178.4	0	0	0	0	0	113.9	Y191 H192 L299 T305	Y191-A303 HydrophobicContact CE1-CB 4.39Å; H192-A303 WeakPolarHBondContact ND1-CB 3.31Å; L299-A303 WeakPolarHBondContact O-CB 3.41Å; L299-A303 PolarHBondContact O-N 3.12Å; L299-A303 VanDerWaalsContact O-N 3.15Å; A303-T305 VanDerWaalsContact C-N 3.28Å; A303-T305 PolarHBondContact O-N 3.37Å
304	D	59.5	Low	70	Confident	102 Å²	102	74.5 Å²	74.5	55%	0.545	36%	0.361	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.9	-14.3	175.6	-94.4	-28.1	0	0	0	113.5	K188 E302	K188-D304 WeakPolarHBondContact CE-OD1 3.27Å; K188-D304 IonicContact NZ-OD1 2.73Å; K188-D304 PolarHBondContact NZ-OD1 2.98Å; E302-D304 PolarHBondContact O-N 3.46Å
305	T	62.3	Low	69.8	Low	70 Å²	70	79.1 Å²	79.1	43%	0.429	38%	0.382	S	S	.	.	S	Bend	trans	-78.7	133.3	179	70.8	0	0	0	0	112.3	E302 A303 K307 A308 F309	E302-T305 PolarHBondContact O-N 3.43Å; E302-T305 PolarHBondContact O-OG1 3.23Å; A303-T305 VanDerWaalsContact C-N 3.28Å; A303-T305 PolarHBondContact O-N 3.37Å; T305-K307 PolarHBondContact O-N 3.38Å; T305-K307 VanDerWaalsContact O-N 3.11Å; T305-A308 WeakPolarHBondContact O-CB 3.04Å; T305-A308 PolarHBondContact O-N 3.22Å; T305-A308 VanDerWaalsContact O-N 3.09Å; T305-F309 WeakPolarHBondContact O-CD1 3.23Å
306	T	58.7	Low	69.9	Low	91 Å²	91	72.2 Å²	72.2	56%	0.558	35%	0.353	S	S	*	.	H	α-helix	trans	-58.4	-28.8	-178.2	-45.9	0	0	0	0	113.8	A308 F309 D310	T306-A308 VanDerWaalsContact C-N 3.31Å; T306-A308 PolarHBondContact O-N 3.12Å; T306-F309 VanDerWaalsContact CA-CE1 3.47Å; T306-F309 HydrophobicContact CG2-CE2 4.11Å; T306-F309 HydrophobicContact CG2-CZ 3.8Å; T306-D310 VanDerWaalsContact O-CB 3.31Å; T306-D310 WeakPolarHBondContact O-CB 3.41Å; T306-D310 PolarHBondContact O-N 2.84Å; T306-D310 VanDerWaalsContact O-N 3.12Å
307	K	63	Low	70	Confident	182 Å²	182	71.2 Å²	71.2	79%	0.791	35%	0.349	S	S	*	.	H	α-helix	trans	-70.2	-25.9	-179.5	-64.8	-179.6	-179.8	178.2	0	113.3	T305	T305-K307 PolarHBondContact O-N 3.38Å; T305-K307 VanDerWaalsContact O-N 3.11Å
308	A	61.5	Low	70.3	Confident	22 Å²	22	74.9 Å²	74.9	18%	0.182	37%	0.368	C	S	.	.	H	α-helix	trans	-73.3	-35.3	-174.4	0	0	0	0	0	112.2	Y191 T305 T306	Y191-A308 HydrophobicContact CD1-CB 4.49Å; Y191-A308 HydrophobicContact CE1-CB 3.6Å; Y191-A308 VanDerWaalsContact CE2-O 3.3Å; Y191-A308 WeakPolarHBondContact CE2-O 3.22Å; Y191-A308 VanDerWaalsContact CZ-O 3.31Å; T305-A308 WeakPolarHBondContact O-CB 3.04Å; T305-A308 PolarHBondContact O-N 3.22Å; T305-A308 VanDerWaalsContact O-N 3.09Å; T306-A308 VanDerWaalsContact C-N 3.31Å; T306-A308 PolarHBondContact O-N 3.12Å
309	F	67.4	Low	71.1	Confident	8 Å²	8	74.9 Å²	74.9	4%	0.035	36%	0.364	C	S	.	.	H	α-helix	trans	-105	-16.4	-179.8	64.3	-101.1	0	0	0	114.3	I184 K188 Y191 T305 T306 L311	I184-F309 HydrophobicContact CG2-CE2 3.72Å; I184-F309 HydrophobicContact CG2-CZ 4.02Å; K188-F309 HydrophobicContact CB-CD1 3.92Å; K188-F309 HydrophobicContact CB-CD2 4.19Å; K188-F309 HydrophobicContact CB-CE1 3.96Å; K188-F309 HydrophobicContact CB-CE2 4.3Å; K188-F309 HydrophobicContact CB-CG 4.02Å; K188-F309 HydrophobicContact CB-CZ 4.14Å; K188-F309 HydrophobicContact CD-CD1 4.22Å; K188-F309 HydrophobicContact CD-CE1 3.68Å; K188-F309 HydrophobicContact CD-CZ 4.19Å; K188-F309 HydrophobicContact CG-CD1 3.75Å; K188-F309 HydrophobicContact CG-CE1 3.72Å; K188-F309 HydrophobicContact CG-CG 4.33Å; K188-F309 HydrophobicContact CG-CZ 4.34Å; Y191-F309 HydrophobicContact CD1-CB 3.82Å; Y191-F309 HydrophobicContact CD2-CB 4.49Å; Y191-F309 HydrophobicContact CG-CB 3.73Å; T305-F309 WeakPolarHBondContact O-CD1 3.23Å; T306-F309 VanDerWaalsContact CA-CE1 3.47Å; T306-F309 HydrophobicContact CG2-CE2 4.11Å; T306-F309 HydrophobicContact CG2-CZ 3.8Å; F309-L311 VanDerWaalsContact C-N 3.3Å; F309-L311 PolarHBondContact O-N 2.89Å
310	D	70.7	Confident	72.1	Confident	40 Å²	40	73.6 Å²	73.6	21%	0.214	36%	0.357	C	S	.	.			trans	-82.6	79.6	173.6	-164.9	20.1	0	0	0	110.9	R187 T306 R312 Q313	R187-D310 IonicContact CZ-OD1 3.58Å; R187-D310 IonicContact NH1-OD1 2.7Å; R187-D310 PolarHBondContact NH1-OD1 3.43Å; R187-D310 IonicContact NH2-OD1 3.56Å; T306-D310 VanDerWaalsContact O-CB 3.31Å; T306-D310 WeakPolarHBondContact O-CB 3.41Å; T306-D310 PolarHBondContact O-N 2.84Å; T306-D310 VanDerWaalsContact O-N 3.12Å; D310-R312 PolarHBondContact O-N 3.04Å; D310-Q313 PolarHBondContact O-N 2.79Å
311	L	71.8	Confident	73.6	Confident	5 Å²	5	72 Å²	72	3%	0.026	35%	0.349	C	S	.	.	G	3₁₀ helix	trans	-61.1	-13.2	-176.9	-73.4	-176.9	0	0	0	114.4	F309 Q313 N314 I317 C368 I369	F309-L311 VanDerWaalsContact C-N 3.3Å; F309-L311 PolarHBondContact O-N 2.89Å; L311-Q313 PolarHBondContact O-N 2.91Å; L311-Q313 VanDerWaalsContact O-N 3.14Å; L311-N314 HydrophobicContact CD2-CB 4.37Å; L311-N314 VanDerWaalsContact O-CB 3.29Å; L311-N314 WeakPolarHBondContact O-CB 3.38Å; L311-N314 PolarHBondContact O-N 3.25Å; L311-I317 HydrophobicContact CB-CG1 4.17Å; L311-I317 WeakPolarHBondContact O-CB 3.27Å; L311-C368 HydrophobicContact CD1-CB 3.47Å; L311-C368 VanDerWaalsContact CD1-CB 3.47Å; L311-I369 HydrophobicContact CD2-CG1 4.47Å
312	R	69.1	Low	75.3	Confident	148 Å²	148	71.4 Å²	71.4	56%	0.558	34%	0.344	S	S	*	.	G	3₁₀ helix	trans	-59.1	-26.5	-180	-67.7	-177.2	178.3	-174.3	-0.3	113.8	D310 L318	D310-R312 PolarHBondContact O-N 3.04Å; R312-L318 WeakPolarHBondContact O-CD2 3.46Å
313	Q	71.8	Confident	77.1	Confident	154 Å²	154	65.8 Å²	65.8	72%	0.72	32%	0.318	S	S	*	.	G	3₁₀ helix	trans	-99.6	-1.6	177.7	-61	-172	0.9	0	0	113.1	D310 L311 H315	D310-Q313 PolarHBondContact O-N 2.79Å; L311-Q313 PolarHBondContact O-N 2.91Å; L311-Q313 VanDerWaalsContact O-N 3.14Å; Q313-H315 PolarHBondContact O-N 3.3Å
314	N	83.6	Confident	78.9	Confident	34 Å²	34	66.1 Å²	66.1	18%	0.182	32%	0.32	C	S	.	.			trans	-70.1	132.2	-179.9	-179.1	-76.2	0	0	0	110.4	L311 S316 I317 L318	L311-N314 HydrophobicContact CD2-CB 4.37Å; L311-N314 VanDerWaalsContact O-CB 3.29Å; L311-N314 WeakPolarHBondContact O-CB 3.38Å; L311-N314 PolarHBondContact O-N 3.25Å; N314-S316 VanDerWaalsContact C-N 3.31Å; N314-S316 PolarHBondContact O-N 2.77Å; N314-S316 WeakPolarHBondContact OD1-CA 3.43Å; N314-S316 VanDerWaalsContact OD1-CB 3.25Å; N314-S316 WeakPolarHBondContact OD1-CB 3.36Å; N314-S316 PolarHBondContact OD1-N 2.89Å; N314-I317 HydrophobicContact CB-CB 4.24Å; N314-I317 HydrophobicContact CB-CG1 3.99Å; N314-I317 PolarHBondContact O-N 2.99Å; N314-I317 PolarHBondContact OD1-N 3.46Å; N314-L318 WeakPolarHBondContact O-CG 3.43Å; N314-L318 PolarHBondContact O-N 3.05Å
315	H	87.3	Confident	80.7	Confident	122 Å²	122	64 Å²	64	57%	0.565	31%	0.311	S	S	*	.	H	α-helix	trans	-62.4	-35.8	-175	-175.9	67.1	0	0	0	113.3	Q313 K319	Q313-H315 PolarHBondContact O-N 3.3Å; H315-K319 WeakPolarHBondContact NE2-CE 3.3Å; H315-K319 PolarHBondContact NE2-NZ 2.71Å; H315-K319 VanDerWaalsContact NE2-NZ 3.16Å; H315-K319 WeakPolarHBondContact O-CG 3.49Å; H315-K319 PolarHBondContact O-N 3.05Å
316	S	89.8	Confident	82.3	Confident	4 Å²	4	64 Å²	64	3%	0.028	30%	0.303	C	S	.	.	H	α-helix	trans	-67.7	-40.9	176.1	-65.4	0	0	0	0	111.7	N314 K319 I320 S362	N314-S316 VanDerWaalsContact C-N 3.31Å; N314-S316 PolarHBondContact O-N 2.77Å; N314-S316 WeakPolarHBondContact OD1-CA 3.43Å; N314-S316 VanDerWaalsContact OD1-CB 3.25Å; N314-S316 WeakPolarHBondContact OD1-CB 3.36Å; N314-S316 PolarHBondContact OD1-N 2.89Å; S316-K319 WeakPolarHBondContact O-CB 3.4Å; S316-K319 PolarHBondContact O-N 3.16Å; S316-I320 VanDerWaalsContact O-CG1 3.29Å; S316-I320 WeakPolarHBondContact O-CG1 3.06Å; S316-I320 PolarHBondContact O-N 2.89Å; S316-S362 WeakPolarHBondContact CB-O 3.03Å; S316-S362 PolarHBondContact OG-O 3.05Å
317	I	88.3	Confident	84.1	Confident	3 Å²	3	59.8 Å²	59.8	2%	0.015	28%	0.277	C	S	.	.	H	α-helix	trans	-65.3	-43.2	175.5	-61.7	-53.4	0	0	0	111.4	L311 N314 K319 I320 E321 I369 A372 Y488	L311-I317 HydrophobicContact CB-CG1 4.17Å; L311-I317 WeakPolarHBondContact O-CB 3.27Å; N314-I317 HydrophobicContact CB-CB 4.24Å; N314-I317 HydrophobicContact CB-CG1 3.99Å; N314-I317 PolarHBondContact O-N 2.99Å; N314-I317 PolarHBondContact OD1-N 3.46Å; I317-K319 VanDerWaalsContact C-N 3.29Å; I317-K319 PolarHBondContact O-N 3.22Å; I317-I320 HydrophobicContact CD1-CD1 4.22Å; I317-I320 PolarHBondContact O-N 3.05Å; I317-I320 VanDerWaalsContact O-N 3.14Å; I317-E321 PolarHBondContact O-N 3.35Å; I317-I369 HydrophobicContact CD1-CB 4.36Å; I317-I369 HydrophobicContact CD1-CG1 3.92Å; I317-I369 HydrophobicContact CD1-CG2 4.4Å; I317-I369 HydrophobicContact CG1-CG1 4.29Å; I317-A372 HydrophobicContact CD1-CB 3.75Å; I317-Y488 HydrophobicContact CD1-CD1 3.61Å; I317-Y488 HydrophobicContact CD1-CE1 3.65Å; I317-Y488 HydrophobicContact CG1-CD1 4.16Å; I317-Y488 HydrophobicContact CG1-CE1 4.45Å; I317-Y488 HydrophobicContact CG2-CD1 3.69Å; I317-Y488 HydrophobicContact CG2-CD2 4.28Å; I317-Y488 HydrophobicContact CG2-CE1 3.74Å; I317-Y488 HydrophobicContact CG2-CE2 4.35Å; I317-Y488 HydrophobicContact CG2-CG 3.97Å
318	L	89.4	Confident	85.6	Confident	92 Å²	92	55.5 Å²	55.5	48%	0.482	26%	0.256	S	S	.	.	H	α-helix	trans	-61.1	-37.3	175.7	-69.1	173.2	0	0	0	112.4	R312 N314 K322	R312-L318 WeakPolarHBondContact O-CD2 3.46Å; N314-L318 WeakPolarHBondContact O-CG 3.43Å; N314-L318 PolarHBondContact O-N 3.05Å; L318-K322 WeakPolarHBondContact O-CB 3.43Å; L318-K322 PolarHBondContact O-N 2.82Å
319	K	92.5	Very high	87.3	Confident	91 Å²	91	58.4 Å²	58.4	40%	0.396	27%	0.265	S	S	.	.	H	α-helix	trans	-63.6	-45.8	172.6	-79.8	174.3	163.8	170.3	0	111.8	H315 S316 I317 K322 V323 V361	H315-K319 WeakPolarHBondContact NE2-CE 3.3Å; H315-K319 PolarHBondContact NE2-NZ 2.71Å; H315-K319 VanDerWaalsContact NE2-NZ 3.16Å; H315-K319 WeakPolarHBondContact O-CG 3.49Å; H315-K319 PolarHBondContact O-N 3.05Å; S316-K319 WeakPolarHBondContact O-CB 3.4Å; S316-K319 PolarHBondContact O-N 3.16Å; I317-K319 VanDerWaalsContact C-N 3.29Å; I317-K319 PolarHBondContact O-N 3.22Å; K319-K322 WeakPolarHBondContact O-CB 3.45Å; K319-K322 PolarHBondContact O-N 3.32Å; K319-V323 PolarHBondContact O-N 2.96Å; K319-V323 VanDerWaalsContact O-N 3.09Å; K319-V361 HydrophobicContact CB-CG2 4.3Å
320	I	92.8	Very high	88.5	Confident	0 Å²	0	58 Å²	58	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-60.4	-46.2	177.4	-67.9	165	0	0	0	110.5	S316 I317 K322 V323 L324 L358 V361 I369 A372 R373 A376	S316-I320 VanDerWaalsContact O-CG1 3.29Å; S316-I320 WeakPolarHBondContact O-CG1 3.06Å; S316-I320 PolarHBondContact O-N 2.89Å; I317-I320 HydrophobicContact CD1-CD1 4.22Å; I317-I320 PolarHBondContact O-N 3.05Å; I317-I320 VanDerWaalsContact O-N 3.14Å; I320-K322 VanDerWaalsContact C-N 3.32Å; I320-K322 PolarHBondContact O-N 3.04Å; I320-V323 WeakPolarHBondContact O-CB 3.42Å; I320-V323 PolarHBondContact O-N 2.68Å; I320-V323 VanDerWaalsContact O-N 3.12Å; I320-L324 HydrophobicContact CG2-CD1 4.1Å; I320-L324 HydrophobicContact CG2-CG 4.41Å; I320-L324 WeakPolarHBondContact O-CG 3.42Å; I320-L324 PolarHBondContact O-N 3.14Å; I320-L358 HydrophobicContact CG1-CD2 4.07Å; I320-L358 HydrophobicContact CG2-CD2 4.46Å; I320-V361 HydrophobicContact CD1-CG1 4.12Å; I320-V361 HydrophobicContact CG1-CG1 4.21Å; I320-V361 HydrophobicContact CG1-CG2 4.12Å; I320-I369 HydrophobicContact CD1-CG2 4.49Å; I320-A372 HydrophobicContact CD1-CB 3.64Å; I320-R373 HydrophobicContact CD1-CB 4.03Å; I320-A376 HydrophobicContact CG2-CB 3.67Å
321	E	92.3	Very high	89.7	Confident	58 Å²	58	57.8 Å²	57.8	27%	0.271	26%	0.261	S	S	.	.	H	α-helix	trans	-63.1	-36.3	178.1	-79.7	-55.4	137.7	0	0	113.3	I317 V323 L324 T325 R328 Y488	I317-E321 PolarHBondContact O-N 3.35Å; E321-V323 VanDerWaalsContact C-N 3.35Å; E321-L324 PolarHBondContact O-N 2.62Å; E321-T325 WeakPolarHBondContact O-CB 3.48Å; E321-T325 PolarHBondContact O-N 2.93Å; E321-T325 PolarHBondContact O-OG1 3.4Å; E321-R328 IonicContact OE2-NH2 3.6Å; E321-Y488 HydrophobicContact CG-CE2 4.37Å; E321-Y488 WeakPolarHBondContact OE1-CE2 3.22Å; E321-Y488 PolarHBondContact OE1-OH 2.93Å
322	K	94.8	Very high	90.7	Very high	151 Å²	151	61.1 Å²	61.1	66%	0.657	28%	0.279	S	S	*	.	H	α-helix	trans	-62.2	-44.2	173.3	-173.7	-177.7	177.7	-173.9	0	111.2	L318 K319 I320 T325 R326	L318-K322 WeakPolarHBondContact O-CB 3.43Å; L318-K322 PolarHBondContact O-N 2.82Å; K319-K322 WeakPolarHBondContact O-CB 3.45Å; K319-K322 PolarHBondContact O-N 3.32Å; I320-K322 VanDerWaalsContact C-N 3.32Å; I320-K322 PolarHBondContact O-N 3.04Å; K322-T325 PolarHBondContact O-N 3.4Å; K322-R326 PolarHBondContact O-N 3.28Å; K322-R326 VanDerWaalsContact O-N 3.1Å
323	V	96.6	Very high	91.7	Very high	4 Å²	4	58.4 Å²	58.4	2%	0.024	27%	0.272	C	S	.	.	H	α-helix	trans	-62	-48.2	175.9	168.9	0	0	0	0	111	K319 I320 E321 T325 R326 M327 L354 Q357 L358 V380	K319-V323 PolarHBondContact O-N 2.96Å; K319-V323 VanDerWaalsContact O-N 3.09Å; I320-V323 WeakPolarHBondContact O-CB 3.42Å; I320-V323 PolarHBondContact O-N 2.68Å; I320-V323 VanDerWaalsContact O-N 3.12Å; E321-V323 VanDerWaalsContact C-N 3.35Å; V323-T325 VanDerWaalsContact C-N 3.29Å; V323-T325 PolarHBondContact O-N 3.29Å; V323-R326 PolarHBondContact O-N 3.01Å; V323-M327 WeakPolarHBondContact O-CB 3.46Å; V323-M327 PolarHBondContact O-N 2.88Å; V323-L354 HydrophobicContact CG1-CB 3.89Å; V323-L354 HydrophobicContact CG1-CD1 4.35Å; V323-L354 HydrophobicContact CG1-CD2 4.21Å; V323-L354 HydrophobicContact CG1-CG 4.37Å; V323-L354 HydrophobicContact CG2-CD2 4.43Å; V323-Q357 HydrophobicContact CG2-CB 4.03Å; V323-L358 HydrophobicContact CB-CD2 4.16Å; V323-L358 HydrophobicContact CB-CG 4.41Å; V323-L358 HydrophobicContact CG1-CD1 3.9Å; V323-L358 HydrophobicContact CG1-CD2 4.05Å; V323-L358 HydrophobicContact CG1-CG 3.87Å; V323-L358 HydrophobicContact CG2-CD2 4.27Å; V323-L358 HydrophobicContact CG2-CG 4.36Å; V323-V380 HydrophobicContact CG1-CG2 4.25Å
324	L	94.3	Very high	92.6	Very high	8 Å²	8	51.5 Å²	51.5	4%	0.042	24%	0.24	C	C	.	.	H	α-helix	trans	-61.6	-38.1	178.8	-72.8	177.4	0	0	0	112.2	I320 E321 M327 R328 A376 E379	I320-L324 HydrophobicContact CG2-CD1 4.1Å; I320-L324 HydrophobicContact CG2-CG 4.41Å; I320-L324 WeakPolarHBondContact O-CG 3.42Å; I320-L324 PolarHBondContact O-N 3.14Å; E321-L324 PolarHBondContact O-N 2.62Å; L324-M327 HydrophobicContact CD2-CE 4.05Å; L324-M327 PolarHBondContact O-N 3.46Å; L324-R328 VanDerWaalsContact O-CG 3.32Å; L324-R328 WeakPolarHBondContact O-CG 3.28Å; L324-R328 PolarHBondContact O-N 2.74Å; L324-A376 HydrophobicContact CD1-CB 4.29Å; L324-A376 HydrophobicContact CD2-CB 3.78Å; L324-A376 HydrophobicContact CG-CB 4.02Å; L324-E379 HydrophobicContact CD2-CB 4.24Å
325	T	95.9	Very high	92.8	Very high	57 Å²	57	53 Å²	53	35%	0.35	25%	0.248	S	C	.	.	H	α-helix	trans	-61.1	-49.1	175.1	-59.8	0	0	0	0	111	E321 K322 V323 M327 R328 E329	E321-T325 WeakPolarHBondContact O-CB 3.48Å; E321-T325 PolarHBondContact O-N 2.93Å; E321-T325 PolarHBondContact O-OG1 3.4Å; K322-T325 PolarHBondContact O-N 3.4Å; V323-T325 VanDerWaalsContact C-N 3.29Å; V323-T325 PolarHBondContact O-N 3.29Å; T325-M327 VanDerWaalsContact C-N 3.34Å; T325-M327 PolarHBondContact O-N 2.92Å; T325-R328 WeakPolarHBondContact O-CB 3.38Å; T325-R328 PolarHBondContact O-N 3Å; T325-R328 PolarHBondContact OG1-NH2 3.48Å; T325-E329 PolarHBondContact O-N 3.49Å; T325-E329 VanDerWaalsContact O-N 3.12Å
326	R	97.3	Very high	92.8	Very high	71 Å²	71	54.7 Å²	54.7	27%	0.268	26%	0.256	S	S	.	.	H	α-helix	trans	-64.7	-38.9	177.7	-174.1	55.9	-177.5	148.1	14.6	112.3	K322 V323 R328 E329 I330 E333 E350 L354	K322-R326 PolarHBondContact O-N 3.28Å; K322-R326 VanDerWaalsContact O-N 3.1Å; V323-R326 PolarHBondContact O-N 3.01Å; R326-R328 VanDerWaalsContact C-N 3.33Å; R326-R328 PolarHBondContact O-N 2.98Å; R326-E329 WeakPolarHBondContact CD-OE2 3.49Å; R326-E329 IonicContact CZ-OE2 3.89Å; R326-E329 IonicContact NE-OE2 2.66Å; R326-E329 IonicContact NH1-OE2 2.88Å; R326-E329 PolarHBondContact NH1-OE2 2.7Å; R326-E329 WeakPolarHBondContact O-CB 3.29Å; R326-E329 PolarHBondContact O-N 3.38Å; R326-I330 HydrophobicContact CG-CD1 4.32Å; R326-I330 WeakPolarHBondContact O-CG1 3.43Å; R326-I330 PolarHBondContact O-N 2.64Å; R326-I330 VanDerWaalsContact O-N 3.08Å; R326-E333 IonicContact NH1-OE1 3.81Å; R326-E350 IonicContact CZ-OE1 3.9Å; R326-E350 IonicContact CZ-OE2 3.21Å; R326-E350 IonicContact NE-OE1 3.59Å; R326-E350 PolarHBondContact NE-OE1 3.04Å; R326-E350 VanDerWaalsContact NH2-CD 3.31Å; R326-E350 IonicContact NH2-OE1 2.6Å; R326-E350 PolarHBondContact NH2-OE1 3.46Å; R326-E350 IonicContact NH2-OE2 2.65Å; R326-E350 PolarHBondContact NH2-OE2 3.36Å; R326-L354 HydrophobicContact CB-CD1 4.33Å; R326-L354 HydrophobicContact CB-CD2 4.35Å; R326-L354 HydrophobicContact CG-CD1 4.26Å; R326-L354 HydrophobicContact CG-CD2 4.28Å
327	M	96.5	Very high	92.6	Very high	2 Å²	2	55.9 Å²	55.9	1%	0.01	27%	0.266	C	S	.	.	H	α-helix	trans	-60.5	-42.4	174.6	-177.8	-82.1	-69.2	0	0	111.7	V323 L324 T325 E329 I330 K331 L351 L354 E379 V380 L383	V323-M327 WeakPolarHBondContact O-CB 3.46Å; V323-M327 PolarHBondContact O-N 2.88Å; L324-M327 HydrophobicContact CD2-CE 4.05Å; L324-M327 PolarHBondContact O-N 3.46Å; T325-M327 VanDerWaalsContact C-N 3.34Å; T325-M327 PolarHBondContact O-N 2.92Å; M327-E329 VanDerWaalsContact C-N 3.32Å; M327-E329 PolarHBondContact O-N 3.34Å; M327-I330 PolarHBondContact O-N 3.22Å; M327-K331 WeakPolarHBondContact O-CB 3.47Å; M327-K331 PolarHBondContact O-N 3.29Å; M327-K331 HydrophobicContact SD-CB 4.44Å; M327-L351 HydrophobicContact CB-CD2 4.47Å; M327-L351 HydrophobicContact CG-CD2 3.88Å; M327-L354 HydrophobicContact CB-CD1 4.07Å; M327-E379 HydrophobicContact CE-CB 3.65Å; M327-E379 HydrophobicContact CE-CG 4.37Å; M327-E379 WeakPolarHBondContact CE-OE2 3.37Å; M327-V380 HydrophobicContact CB-CG2 4.17Å; M327-V380 HydrophobicContact CG-CG2 3.92Å; M327-L383 HydrophobicContact CG-CD2 4.11Å; M327-L383 HydrophobicContact SD-CD2 4Å
328	R	95.1	Very high	91.7	Very high	91 Å²	91	64.7 Å²	64.7	34%	0.343	31%	0.307	S	S	.	.	H	α-helix	trans	-61.7	-38.7	176.1	-74.9	-178.1	-68.7	-104.3	5.3	112.3	E321 L324 T325 R326 K331 N332	E321-R328 IonicContact OE2-NH2 3.6Å; L324-R328 VanDerWaalsContact O-CG 3.32Å; L324-R328 WeakPolarHBondContact O-CG 3.28Å; L324-R328 PolarHBondContact O-N 2.74Å; T325-R328 WeakPolarHBondContact O-CB 3.38Å; T325-R328 PolarHBondContact O-N 3Å; T325-R328 PolarHBondContact OG1-NH2 3.48Å; R326-R328 VanDerWaalsContact C-N 3.33Å; R326-R328 PolarHBondContact O-N 2.98Å; R328-K331 WeakPolarHBondContact O-CB 3.39Å; R328-K331 PolarHBondContact O-N 2.73Å; R328-N332 WeakPolarHBondContact O-CB 3.48Å; R328-N332 PolarHBondContact O-N 3.4Å; R328-N332 PolarHBondContact O-ND2 2.89Å; R328-N332 PolarHBondContact O-OD1 3.36Å
329	E	95.3	Very high	90.8	Very high	83 Å²	83	65.2 Å²	65.2	39%	0.388	31%	0.311	S	S	.	.	H	α-helix	trans	-60.5	-53	173.7	-67.3	167.5	-172.8	0	0	110.9	T325 R326 M327 K331 N332 E333	T325-E329 PolarHBondContact O-N 3.49Å; T325-E329 VanDerWaalsContact O-N 3.12Å; R326-E329 WeakPolarHBondContact CD-OE2 3.49Å; R326-E329 IonicContact CZ-OE2 3.89Å; R326-E329 IonicContact NE-OE2 2.66Å; R326-E329 IonicContact NH1-OE2 2.88Å; R326-E329 PolarHBondContact NH1-OE2 2.7Å; R326-E329 WeakPolarHBondContact O-CB 3.29Å; R326-E329 PolarHBondContact O-N 3.38Å; M327-E329 VanDerWaalsContact C-N 3.32Å; M327-E329 PolarHBondContact O-N 3.34Å; E329-K331 VanDerWaalsContact C-N 3.29Å; E329-K331 PolarHBondContact O-N 2.7Å; E329-N332 PolarHBondContact O-N 2.9Å; E329-N332 VanDerWaalsContact O-N 3.09Å; E329-E333 WeakPolarHBondContact O-CG 3.4Å; E329-E333 PolarHBondContact O-N 2.9Å
330	I	94.6	Very high	89.8	Confident	0 Å²	0	62.6 Å²	62.6	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-57.5	-42.9	177.8	-63.1	166.2	0	0	0	111	R326 M327 N332 E333 L334 E350 L351 L354 L383	R326-I330 HydrophobicContact CG-CD1 4.32Å; R326-I330 WeakPolarHBondContact O-CG1 3.43Å; R326-I330 PolarHBondContact O-N 2.64Å; R326-I330 VanDerWaalsContact O-N 3.08Å; M327-I330 PolarHBondContact O-N 3.22Å; I330-N332 PolarHBondContact O-N 3.4Å; I330-E333 PolarHBondContact O-N 2.93Å; I330-L334 HydrophobicContact CG2-CD1 3.91Å; I330-L334 HydrophobicContact CG2-CG 4.43Å; I330-L334 WeakPolarHBondContact O-CB 3.4Å; I330-L334 VanDerWaalsContact O-CG 3.29Å; I330-L334 WeakPolarHBondContact O-CG 3.44Å; I330-L334 PolarHBondContact O-N 3.15Å; I330-E350 HydrophobicContact CD1-CB 4.11Å; I330-E350 HydrophobicContact CD1-CG 3.69Å; I330-L351 HydrophobicContact CD1-CD2 4.08Å; I330-L351 HydrophobicContact CD1-CG 4.28Å; I330-L351 HydrophobicContact CG2-CD1 4.28Å; I330-L351 HydrophobicContact CG2-CD2 4.38Å; I330-L351 HydrophobicContact CG2-CG 4.26Å; I330-L354 HydrophobicContact CD1-CD1 4.08Å; I330-L383 HydrophobicContact CG2-CD2 4.38Å
331	K	94.3	Very high	89.2	Confident	35 Å²	35	66.1 Å²	66.1	15%	0.152	33%	0.325	C	S	.	.	H	α-helix	trans	-58.2	-48.2	176.2	-173.9	-170.8	71	168.3	0	111.3	M327 R328 E329 L334 L335 L383 L425	M327-K331 WeakPolarHBondContact O-CB 3.47Å; M327-K331 PolarHBondContact O-N 3.29Å; M327-K331 HydrophobicContact SD-CB 4.44Å; R328-K331 WeakPolarHBondContact O-CB 3.39Å; R328-K331 PolarHBondContact O-N 2.73Å; E329-K331 VanDerWaalsContact C-N 3.29Å; E329-K331 PolarHBondContact O-N 2.7Å; K331-L334 PolarHBondContact O-N 2.71Å; K331-L335 HydrophobicContact CD-CD1 4.47Å; K331-L335 HydrophobicContact CG-CD1 3.98Å; K331-L335 HydrophobicContact CG-CG 4.47Å; K331-L335 WeakPolarHBondContact O-CG 3.35Å; K331-L335 PolarHBondContact O-N 2.72Å; K331-L383 HydrophobicContact CB-CD1 4.46Å; K331-L383 HydrophobicContact CB-CD2 3.84Å; K331-L383 HydrophobicContact CG-CD1 4.22Å; K331-L383 HydrophobicContact CG-CD2 4.42Å; K331-L425 HydrophobicContact CD-CB 4.4Å; K331-L425 HydrophobicContact CD-CD2 4.42Å; K331-L425 PolarHBondContact NZ-O 2.99Å
332	N	92.6	Very high	88.6	Confident	75 Å²	75	70.7 Å²	70.7	40%	0.401	35%	0.347	S	S	.	.	H	α-helix	trans	-66.1	-41.8	-178.2	-69.2	-16.5	0	0	0	111.2	R328 E329 I330 L334 L335 Q336	R328-N332 WeakPolarHBondContact O-CB 3.48Å; R328-N332 PolarHBondContact O-N 3.4Å; R328-N332 PolarHBondContact O-ND2 2.89Å; R328-N332 PolarHBondContact O-OD1 3.36Å; E329-N332 PolarHBondContact O-N 2.9Å; E329-N332 VanDerWaalsContact O-N 3.09Å; I330-N332 PolarHBondContact O-N 3.4Å; N332-L334 VanDerWaalsContact C-N 3.35Å; N332-L334 PolarHBondContact O-N 3.29Å; N332-L335 PolarHBondContact O-N 3.44Å; N332-Q336 WeakPolarHBondContact O-CB 3.39Å; N332-Q336 VanDerWaalsContact O-CG 3.31Å; N332-Q336 WeakPolarHBondContact O-CG 3.22Å; N332-Q336 PolarHBondContact O-N 2.97Å; N332-Q336 VanDerWaalsContact O-N 3.08Å
333	E	91.7	Very high	88.2	Confident	92 Å²	92	66.3 Å²	66.3	43%	0.43	33%	0.33	S	S	.	.	H	α-helix	trans	-57.6	-46.5	173.5	-70.7	170.6	-165.4	0	0	111.2	R326 E329 I330 Q336 A337	R326-E333 IonicContact NH1-OE1 3.81Å; E329-E333 WeakPolarHBondContact O-CG 3.4Å; E329-E333 PolarHBondContact O-N 2.9Å; I330-E333 PolarHBondContact O-N 2.93Å; E333-Q336 PolarHBondContact O-N 2.64Å; E333-A337 WeakPolarHBondContact O-CB 3.34Å; E333-A337 PolarHBondContact O-N 3.04Å
334	L	90.6	Very high	87.9	Confident	8 Å²	8	66.9 Å²	66.9	4%	0.042	33%	0.332	C	S	.	.	H	α-helix	trans	-64.9	-43.3	179.3	-75.7	168.5	0	0	0	113.4	I330 K331 N332 Q336 L343 Y344 L383 I387	I330-L334 HydrophobicContact CG2-CD1 3.91Å; I330-L334 HydrophobicContact CG2-CG 4.43Å; I330-L334 WeakPolarHBondContact O-CB 3.4Å; I330-L334 VanDerWaalsContact O-CG 3.29Å; I330-L334 WeakPolarHBondContact O-CG 3.44Å; I330-L334 PolarHBondContact O-N 3.15Å; K331-L334 PolarHBondContact O-N 2.71Å; N332-L334 VanDerWaalsContact C-N 3.35Å; N332-L334 PolarHBondContact O-N 3.29Å; L334-Q336 VanDerWaalsContact C-N 3.32Å; L334-L343 HydrophobicContact CD2-CB 4.07Å; L334-Y344 HydrophobicContact CD2-CD1 3.99Å; L334-Y344 HydrophobicContact CD2-CE1 4.31Å; L334-L383 HydrophobicContact CD1-CD1 4.13Å; L334-L383 HydrophobicContact CD1-CD2 4.42Å; L334-L383 HydrophobicContact CD1-CG 4.35Å; L334-I387 HydrophobicContact CD1-CD1 3.71Å; L334-I387 HydrophobicContact CD1-CG1 4.01Å
335	L	87.1	Confident	87.7	Confident	65 Å²	65	72.5 Å²	72.5	34%	0.34	36%	0.361	S	S	.	.	H	α-helix	trans	-73.6	-24	-177.6	-68.2	177.6	0	0	0	112.8	K331 N332 Y386	K331-L335 HydrophobicContact CD-CD1 4.47Å; K331-L335 HydrophobicContact CG-CD1 3.98Å; K331-L335 HydrophobicContact CG-CG 4.47Å; K331-L335 WeakPolarHBondContact O-CG 3.35Å; K331-L335 PolarHBondContact O-N 2.72Å; N332-L335 PolarHBondContact O-N 3.44Å; L335-Y386 HydrophobicContact CD2-CE1 4.42Å
336	Q	87.1	Confident	87.5	Confident	159 Å²	159	72.8 Å²	72.8	74%	0.743	37%	0.366	S	S	*	.	H	α-helix	trans	-100.9	-8.1	-178.6	-64	179.1	4.4	0	0	113.8	N332 E333 L334	N332-Q336 WeakPolarHBondContact O-CB 3.39Å; N332-Q336 VanDerWaalsContact O-CG 3.31Å; N332-Q336 WeakPolarHBondContact O-CG 3.22Å; N332-Q336 PolarHBondContact O-N 2.97Å; N332-Q336 VanDerWaalsContact O-N 3.08Å; E333-Q336 PolarHBondContact O-N 2.64Å; L334-Q336 VanDerWaalsContact C-N 3.32Å
337	A	84.9	Confident	87.3	Confident	28 Å²	28	69.6 Å²	69.6	23%	0.231	36%	0.355	C	S	.	.			trans	-63.6	136.1	-176.5	0	0	0	0	0	112.9	E333 P340 L343	E333-A337 WeakPolarHBondContact O-CB 3.34Å; E333-A337 PolarHBondContact O-N 3.04Å; A337-P340 HydrophobicContact CB-CG 4.29Å; A337-L343 HydrophobicContact CB-CD1 3.54Å
338	Q	69.8	Low	87.2	Confident	188 Å²	188	72.3 Å²	72.3	88%	0.879	37%	0.366	S	S	*	.	S	Bend	trans	-74.4	-31.2	172.5	-65.6	-178.6	29.1	0	0	112.2	P340	Q338-P340 VanDerWaalsContact C-CD 3.48Å; Q338-P340 WeakPolarHBondContact O-CD 3.5Å
339	N	70.4	Confident	87.2	Confident	104 Å²	104	72.3 Å²	72.3	56%	0.556	38%	0.377	S	S	*	.	S	Bend	trans	-122.8	73.3	174.2	-67.8	-28.3	0	0	0	111.3	E342	N339-E342 PolarHBondContact O-N 3.07Å
340	P	72.3	Confident	87.3	Confident	36 Å²	36	71.8 Å²	71.8	23%	0.234	37%	0.374	C	S	.	.	H	α-helix	trans	-55.8	-37.5	-177.9	-22.3	31.3	0	0	0	115.8	A337 Q338 E342 L343 Y344	A337-P340 HydrophobicContact CB-CG 4.29Å; Q338-P340 VanDerWaalsContact C-CD 3.48Å; Q338-P340 WeakPolarHBondContact O-CD 3.5Å; P340-E342 VanDerWaalsContact C-N 3.27Å; P340-E342 PolarHBondContact O-N 3.31Å; P340-L343 PolarHBondContact O-N 3.49Å; P340-L343 VanDerWaalsContact O-N 3.08Å; P340-Y344 HydrophobicContact CB-CE1 3.73Å; P340-Y344 WeakPolarHBondContact CB-OH 3.32Å; P340-Y344 WeakPolarHBondContact O-CD1 3.46Å; P340-Y344 WeakPolarHBondContact O-CE1 3.47Å; P340-Y344 PolarHBondContact O-N 2.9Å
341	P	78.8	Confident	87.4	Confident	73 Å²	73	71.8 Å²	71.8	47%	0.474	37%	0.374	S	S	.	.	H	α-helix	trans	-61.1	-28.7	-175	-26.9	36.1	0	0	0	115.8	L343 Y344	P341-L343 VanDerWaalsContact C-N 3.27Å; P341-L343 PolarHBondContact O-N 3.47Å; P341-Y344 HydrophobicContact CB-CD2 4.38Å; P341-Y344 HydrophobicContact CB-CE2 4.23Å; P341-Y344 HydrophobicContact CG-CE2 4.29Å
342	E	81.3	Confident	87.6	Confident	154 Å²	154	74.5 Å²	74.5	72%	0.72	39%	0.388	S	S	*	.	H	α-helix	trans	-72.6	-23.7	179.4	-65.6	179.1	172.3	0	0	112.1	N339 P340	N339-E342 PolarHBondContact O-N 3.07Å; P340-E342 VanDerWaalsContact C-N 3.27Å; P340-E342 PolarHBondContact O-N 3.31Å
343	L	85.9	Confident	87.8	Confident	59 Å²	59	72.8 Å²	72.8	31%	0.309	39%	0.387	S	S	.	.	H	α-helix	trans	-91.1	-19.5	-177.7	-61.1	176	0	0	0	113.2	L334 A337 P340 P341 L345 S346 S347	L334-L343 HydrophobicContact CD2-CB 4.07Å; A337-L343 HydrophobicContact CB-CD1 3.54Å; P340-L343 PolarHBondContact O-N 3.49Å; P340-L343 VanDerWaalsContact O-N 3.08Å; P341-L343 VanDerWaalsContact C-N 3.27Å; P341-L343 PolarHBondContact O-N 3.47Å; L343-L345 PolarHBondContact O-N 3.07Å; L343-S346 PolarHBondContact O-N 3.36Å; L343-S346 PolarHBondContact O-OG 3.42Å; L343-S347 VanDerWaalsContact O-CB 3.29Å; L343-S347 WeakPolarHBondContact O-CB 3.49Å; L343-S347 PolarHBondContact O-N 3.12Å; L343-S347 PolarHBondContact O-OG 3.09Å
344	Y	89.7	Confident	88.1	Confident	17 Å²	17	68.7 Å²	68.7	7%	0.067	37%	0.368	C	S	.	.	H	α-helix	trans	-55.9	-46.9	-173.3	-68.4	-18.2	0	0	0	113.1	L334 P340 P341 K348 I387 K390 E391	L334-Y344 HydrophobicContact CD2-CD1 3.99Å; L334-Y344 HydrophobicContact CD2-CE1 4.31Å; P340-Y344 HydrophobicContact CB-CE1 3.73Å; P340-Y344 WeakPolarHBondContact CB-OH 3.32Å; P340-Y344 WeakPolarHBondContact O-CD1 3.46Å; P340-Y344 WeakPolarHBondContact O-CE1 3.47Å; P340-Y344 PolarHBondContact O-N 2.9Å; P341-Y344 HydrophobicContact CB-CD2 4.38Å; P341-Y344 HydrophobicContact CB-CE2 4.23Å; P341-Y344 HydrophobicContact CG-CE2 4.29Å; Y344-K348 WeakPolarHBondContact O-CB 3.15Å; Y344-K348 PolarHBondContact O-N 3.38Å; Y344-I387 HydrophobicContact CD1-CG2 4.01Å; Y344-I387 HydrophobicContact CG-CG2 3.84Å; Y344-K390 HydrophobicContact CE1-CB 4.38Å; Y344-K390 HydrophobicContact CE2-CB 3.84Å; Y344-K390 WeakPolarHBondContact OH-CB 3.37Å; Y344-E391 WeakPolarHBondContact CB-OE1 3.39Å; Y344-E391 HydrophobicContact CD2-CG 3.57Å; Y344-E391 HydrophobicContact CE2-CG 4.4Å; Y344-E391 HydrophobicContact CG-CG 4.15Å
345	L	90.2	Very high	88.4	Confident	125 Å²	125	69.2 Å²	69.2	65%	0.654	37%	0.371	S	S	*	.	H	α-helix	trans	-65.6	-46	-178.5	-178.3	62.7	0	0	0	112.3	L343 T349	L343-L345 PolarHBondContact O-N 3.07Å; L345-T349 WeakPolarHBondContact O-CB 3.45Å; L345-T349 PolarHBondContact O-N 2.95Å; L345-T349 PolarHBondContact O-OG1 3.38Å
346	S	92.3	Very high	88.8	Confident	64 Å²	64	67.5 Å²	67.5	45%	0.448	37%	0.369	S	S	.	.	H	α-helix	trans	-66.1	-48.2	179.7	51.7	0	0	0	0	111.2	L343 K348 T349 E350	L343-S346 PolarHBondContact O-N 3.36Å; L343-S346 PolarHBondContact O-OG 3.42Å; S346-K348 PolarHBondContact O-N 3.29Å; S346-T349 PolarHBondContact O-N 3.41Å; S346-E350 PolarHBondContact O-N 3.1Å
347	S	93.1	Very high	89.3	Confident	4 Å²	4	64.4 Å²	64.4	3%	0.028	35%	0.354	C	S	.	.	H	α-helix	trans	-64	-41.5	-179.9	-60.3	0	0	0	0	111.6	L343 T349 E350 L351	L343-S347 VanDerWaalsContact O-CB 3.29Å; L343-S347 WeakPolarHBondContact O-CB 3.49Å; L343-S347 PolarHBondContact O-N 3.12Å; L343-S347 PolarHBondContact O-OG 3.09Å; S347-T349 PolarHBondContact O-N 2.87Å; S347-E350 PolarHBondContact O-N 2.85Å; S347-L351 WeakPolarHBondContact O-CB 3.2Å; S347-L351 WeakPolarHBondContact O-CD1 3.29Å; S347-L351 WeakPolarHBondContact O-CG 3.48Å; S347-L351 PolarHBondContact O-N 3.2Å
348	K	94.8	Very high	89.8	Confident	58 Å²	58	63 Å²	63	25%	0.252	34%	0.343	S	S	.	.	H	α-helix	trans	-63.2	-42	176	-178	175.8	175.4	-179.8	0	112.2	Y344 S346 E350 L351 Q352 I384 I387 D388	Y344-K348 WeakPolarHBondContact O-CB 3.15Å; Y344-K348 PolarHBondContact O-N 3.38Å; S346-K348 PolarHBondContact O-N 3.29Å; K348-E350 VanDerWaalsContact C-N 3.33Å; K348-L351 PolarHBondContact O-N 3.26Å; K348-Q352 WeakPolarHBondContact O-CG 3.44Å; K348-Q352 PolarHBondContact O-N 3.46Å; K348-I384 HydrophobicContact CG-CG2 4.38Å; K348-I387 HydrophobicContact CB-CD1 4.34Å; K348-I387 HydrophobicContact CB-CG2 4.37Å; K348-D388 WeakPolarHBondContact CE-OD1 3.46Å; K348-D388 IonicContact NZ-OD1 3.82Å; K348-D388 PolarHBondContact NZ-OD1 2.77Å; K348-D388 IonicContact NZ-OD2 2.98Å
349	T	95.4	Very high	90.9	Very high	92 Å²	92	59 Å²	59	56%	0.564	33%	0.327	S	S	*	.	H	α-helix	trans	-63.1	-43	177.4	-56.4	0	0	0	0	110.9	L345 S346 S347 Q352 G353	L345-T349 WeakPolarHBondContact O-CB 3.45Å; L345-T349 PolarHBondContact O-N 2.95Å; L345-T349 PolarHBondContact O-OG1 3.38Å; S346-T349 PolarHBondContact O-N 3.41Å; S347-T349 PolarHBondContact O-N 2.87Å; T349-Q352 PolarHBondContact O-N 2.92Å; T349-G353 PolarHBondContact O-N 3.11Å; T349-G353 VanDerWaalsContact O-N 3.1Å
350	E	97.1	Very high	91.9	Very high	71 Å²	71	61.7 Å²	61.7	33%	0.332	34%	0.337	S	S	.	.	H	α-helix	trans	-65	-44.2	176.8	-170.2	171.7	-174.7	0	0	112.1	R326 I330 S346 S347 K348 Q352 G353 L354	R326-E350 IonicContact CZ-OE1 3.9Å; R326-E350 IonicContact CZ-OE2 3.21Å; R326-E350 IonicContact NE-OE1 3.59Å; R326-E350 PolarHBondContact NE-OE1 3.04Å; R326-E350 VanDerWaalsContact NH2-CD 3.31Å; R326-E350 IonicContact NH2-OE1 2.6Å; R326-E350 PolarHBondContact NH2-OE1 3.46Å; R326-E350 IonicContact NH2-OE2 2.65Å; R326-E350 PolarHBondContact NH2-OE2 3.36Å; I330-E350 HydrophobicContact CD1-CB 4.11Å; I330-E350 HydrophobicContact CD1-CG 3.69Å; S346-E350 PolarHBondContact O-N 3.1Å; S347-E350 PolarHBondContact O-N 2.85Å; K348-E350 VanDerWaalsContact C-N 3.33Å; E350-Q352 VanDerWaalsContact C-N 3.32Å; E350-Q352 PolarHBondContact O-N 3.27Å; E350-G353 CarbonylContact O-C 3.57Å; E350-G353 WeakPolarHBondContact O-CA 3.49Å; E350-G353 PolarHBondContact O-N 3.09Å; E350-L354 PolarHBondContact O-N 3.18Å
351	L	97.2	Very high	92.8	Very high	0 Å²	0	60.3 Å²	60.3	0%	0	33%	0.328	C	S	.	.	H	α-helix	trans	-61.1	-38	176.4	-69.8	164.4	0	0	0	112.4	M327 I330 S347 K348 G353 L354 I355 V380 L383 I384 I387	M327-L351 HydrophobicContact CB-CD2 4.47Å; M327-L351 HydrophobicContact CG-CD2 3.88Å; I330-L351 HydrophobicContact CD1-CD2 4.08Å; I330-L351 HydrophobicContact CD1-CG 4.28Å; I330-L351 HydrophobicContact CG2-CD1 4.28Å; I330-L351 HydrophobicContact CG2-CD2 4.38Å; I330-L351 HydrophobicContact CG2-CG 4.26Å; S347-L351 WeakPolarHBondContact O-CB 3.2Å; S347-L351 WeakPolarHBondContact O-CD1 3.29Å; S347-L351 WeakPolarHBondContact O-CG 3.48Å; S347-L351 PolarHBondContact O-N 3.2Å; K348-L351 PolarHBondContact O-N 3.26Å; L351-G353 VanDerWaalsContact C-N 3.32Å; L351-L354 HydrophobicContact CD2-CD1 4.25Å; L351-L354 WeakPolarHBondContact O-CB 3.36Å; L351-L354 PolarHBondContact O-N 2.92Å; L351-I355 PolarHBondContact O-N 2.91Å; L351-V380 HydrophobicContact CB-CG1 4.1Å; L351-V380 HydrophobicContact CD2-CG1 3.99Å; L351-V380 WeakPolarHBondContact O-CG1 3.48Å; L351-L383 HydrophobicContact CD1-CB 4.21Å; L351-L383 HydrophobicContact CD1-CD2 3.83Å; L351-L383 HydrophobicContact CD1-CG 3.76Å; L351-L383 HydrophobicContact CD2-CD2 3.8Å; L351-L383 HydrophobicContact CD2-CG 4.46Å; L351-L383 HydrophobicContact CG-CD2 4.46Å; L351-I384 HydrophobicContact CB-CD1 3.87Å; L351-I384 HydrophobicContact CB-CG1 3.59Å; L351-I384 HydrophobicContact CD1-CG1 3.99Å; L351-I384 HydrophobicContact CG-CG1 4.39Å; L351-I387 HydrophobicContact CD1-CD1 3.62Å
352	Q	97.3	Very high	93	Very high	93 Å²	93	60 Å²	60	44%	0.435	33%	0.327	S	S	.	.	H	α-helix	trans	-63.6	-38.7	172.2	-73.3	-71.5	-9.8	0	0	111.8	K348 T349 E350 L354 I355 G356 I384	K348-Q352 WeakPolarHBondContact O-CG 3.44Å; K348-Q352 PolarHBondContact O-N 3.46Å; T349-Q352 PolarHBondContact O-N 2.92Å; E350-Q352 VanDerWaalsContact C-N 3.32Å; E350-Q352 PolarHBondContact O-N 3.27Å; Q352-L354 VanDerWaalsContact C-N 3.3Å; Q352-L354 PolarHBondContact O-N 2.99Å; Q352-I355 WeakPolarHBondContact O-CB 3.32Å; Q352-I355 PolarHBondContact O-N 3.35Å; Q352-G356 PolarHBondContact O-N 3.34Å; Q352-G356 VanDerWaalsContact O-N 3.13Å; Q352-I384 HydrophobicContact CG-CD1 4.27Å
353	G	97.2	Very high	92.6	Very high	38 Å²	38	54.7 Å²	54.7	39%	0.392	30%	0.304	S	S	.	.	H	α-helix	trans	-62.2	-35.6	171.4	0	0	0	0	0	113.1	T349 E350 L351 G356 Q357	T349-G353 PolarHBondContact O-N 3.11Å; T349-G353 VanDerWaalsContact O-N 3.1Å; E350-G353 CarbonylContact O-C 3.57Å; E350-G353 WeakPolarHBondContact O-CA 3.49Å; E350-G353 PolarHBondContact O-N 3.09Å; L351-G353 VanDerWaalsContact C-N 3.32Å; G353-G356 PolarHBondContact O-N 3.36Å; G353-Q357 PolarHBondContact O-N 3.44Å; G353-Q357 VanDerWaalsContact O-N 3.08Å
354	L	97.6	Very high	91.8	Very high	6 Å²	6	57.1 Å²	57.1	3%	0.031	31%	0.313	C	S	.	.	H	α-helix	trans	-67.2	-36.5	173.9	-66.4	-176.3	0	0	0	112.5	V323 R326 M327 I330 E350 L351 Q352 Q357 L358 V380	V323-L354 HydrophobicContact CG1-CB 3.89Å; V323-L354 HydrophobicContact CG1-CD1 4.35Å; V323-L354 HydrophobicContact CG1-CD2 4.21Å; V323-L354 HydrophobicContact CG1-CG 4.37Å; V323-L354 HydrophobicContact CG2-CD2 4.43Å; R326-L354 HydrophobicContact CB-CD1 4.33Å; R326-L354 HydrophobicContact CB-CD2 4.35Å; R326-L354 HydrophobicContact CG-CD1 4.26Å; R326-L354 HydrophobicContact CG-CD2 4.28Å; M327-L354 HydrophobicContact CB-CD1 4.07Å; I330-L354 HydrophobicContact CD1-CD1 4.08Å; E350-L354 PolarHBondContact O-N 3.18Å; L351-L354 HydrophobicContact CD2-CD1 4.25Å; L351-L354 WeakPolarHBondContact O-CB 3.36Å; L351-L354 PolarHBondContact O-N 2.92Å; Q352-L354 VanDerWaalsContact C-N 3.3Å; Q352-L354 PolarHBondContact O-N 2.99Å; L354-Q357 PolarHBondContact O-N 3Å; L354-L358 WeakPolarHBondContact O-CG 3.37Å; L354-L358 PolarHBondContact O-N 2.91Å; L354-V380 HydrophobicContact CB-CG1 4.37Å
355	I	96.9	Very high	90.7	Very high	20 Å²	20	62.9 Å²	62.9	10%	0.103	34%	0.339	C	S	.	.	H	α-helix	trans	-60.6	-45.8	171.3	-64.8	-61.9	0	0	0	110.5	L351 Q352 Q357 L358 D359 V377 V380 I384	L351-I355 PolarHBondContact O-N 2.91Å; Q352-I355 WeakPolarHBondContact O-CB 3.32Å; Q352-I355 PolarHBondContact O-N 3.35Å; I355-Q357 VanDerWaalsContact C-N 3.29Å; I355-Q357 PolarHBondContact O-N 2.9Å; I355-L358 HydrophobicContact CD1-CD1 4.44Å; I355-L358 WeakPolarHBondContact O-CA 3.5Å; I355-L358 WeakPolarHBondContact O-CB 3.32Å; I355-L358 PolarHBondContact O-N 3.07Å; I355-D359 PolarHBondContact O-N 3.28Å; I355-V377 HydrophobicContact CD1-CB 4.49Å; I355-V377 HydrophobicContact CD1-CG1 4.16Å; I355-V377 HydrophobicContact CD1-CG2 4.5Å; I355-V380 HydrophobicContact CD1-CB 3.66Å; I355-V380 HydrophobicContact CD1-CG1 3.49Å; I355-V380 VanDerWaalsContact CD1-CG1 3.49Å; I355-V380 HydrophobicContact CG1-CB 4.44Å; I355-V380 HydrophobicContact CG1-CG1 3.71Å; I355-I384 HydrophobicContact CG1-CD1 4.28Å
356	G	96.1	Very high	89.9	Confident	29 Å²	29	57.7 Å²	57.7	30%	0.299	31%	0.312	S	S	.	.	H	α-helix	trans	-57.7	-40.6	175.4	0	0	0	0	0	113	Q352 G353 L358 D359 E360	Q352-G356 PolarHBondContact O-N 3.34Å; Q352-G356 VanDerWaalsContact O-N 3.13Å; G353-G356 PolarHBondContact O-N 3.36Å; G356-L358 VanDerWaalsContact C-N 3.32Å; G356-L358 PolarHBondContact O-N 3.27Å; G356-D359 PolarHBondContact O-N 2.94Å; G356-E360 PolarHBondContact O-N 3.21Å
357	Q	96.2	Very high	89.1	Confident	93 Å²	93	55.1 Å²	55.1	44%	0.435	29%	0.293	S	S	.	.	H	α-helix	trans	-63.9	-36	174.1	-71.1	176.2	50.9	0	0	112.8	V323 G353 L354 I355 E360	V323-Q357 HydrophobicContact CG2-CB 4.03Å; G353-Q357 PolarHBondContact O-N 3.44Å; G353-Q357 VanDerWaalsContact O-N 3.08Å; L354-Q357 PolarHBondContact O-N 3Å; I355-Q357 VanDerWaalsContact C-N 3.29Å; I355-Q357 PolarHBondContact O-N 2.9Å; Q357-E360 PolarHBondContact O-N 2.8Å
358	L	95.3	Very high	88.4	Confident	0 Å²	0	55 Å²	55	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-68.7	-37.8	175.5	-71	168.6	0	0	0	111.5	I320 V323 L354 I355 G356 E360 V361 R373 A376 V377 V380	I320-L358 HydrophobicContact CG1-CD2 4.07Å; I320-L358 HydrophobicContact CG2-CD2 4.46Å; V323-L358 HydrophobicContact CB-CD2 4.16Å; V323-L358 HydrophobicContact CB-CG 4.41Å; V323-L358 HydrophobicContact CG1-CD1 3.9Å; V323-L358 HydrophobicContact CG1-CD2 4.05Å; V323-L358 HydrophobicContact CG1-CG 3.87Å; V323-L358 HydrophobicContact CG2-CD2 4.27Å; V323-L358 HydrophobicContact CG2-CG 4.36Å; L354-L358 WeakPolarHBondContact O-CG 3.37Å; L354-L358 PolarHBondContact O-N 2.91Å; I355-L358 HydrophobicContact CD1-CD1 4.44Å; I355-L358 WeakPolarHBondContact O-CA 3.5Å; I355-L358 WeakPolarHBondContact O-CB 3.32Å; I355-L358 PolarHBondContact O-N 3.07Å; G356-L358 VanDerWaalsContact C-N 3.32Å; G356-L358 PolarHBondContact O-N 3.27Å; L358-E360 PolarHBondContact O-N 3.22Å; L358-V361 VanDerWaalsContact O-CB 3.29Å; L358-V361 WeakPolarHBondContact O-CB 3.45Å; L358-V361 WeakPolarHBondContact O-CG2 3.48Å; L358-V361 PolarHBondContact O-N 3.13Å; L358-V361 VanDerWaalsContact O-N 3.07Å; L358-R373 HydrophobicContact CB-CG 4.26Å; L358-R373 HydrophobicContact CD2-CG 4.42Å; L358-R373 WeakPolarHBondContact O-CD 3.34Å; L358-A376 HydrophobicContact CD1-CB 4.03Å; L358-A376 HydrophobicContact CD2-CB 3.89Å; L358-V377 HydrophobicContact CB-CG2 3.94Å; L358-V377 HydrophobicContact CD1-CB 4.48Å; L358-V377 HydrophobicContact CD1-CG2 3.74Å; L358-V377 HydrophobicContact CG-CG2 4.43Å; L358-V380 HydrophobicContact CD1-CG2 4.18Å
359	D	93.5	Very high	87.8	Confident	102 Å²	102	52.3 Å²	52.3	55%	0.545	28%	0.281	S	S	.	.	H	α-helix	trans	-63.6	-31	177.2	-71.3	-24.2	0	0	0	112.5	I355 G356 V361	I355-D359 PolarHBondContact O-N 3.28Å; G356-D359 PolarHBondContact O-N 2.94Å; D359-V361 VanDerWaalsContact C-N 3.29Å; D359-V361 PolarHBondContact O-N 3.01Å
360	E	92.3	Very high	87.3	Confident	162 Å²	162	51.8 Å²	51.8	76%	0.757	27%	0.269	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.1	-7.3	174.8	-68	178.5	-174.7	0	0	114.1	G356 Q357 L358 S362	G356-E360 PolarHBondContact O-N 3.21Å; Q357-E360 PolarHBondContact O-N 2.8Å; L358-E360 PolarHBondContact O-N 3.22Å; E360-S362 PolarHBondContact O-N 3.21Å
361	V	90.5	Very high	86.7	Confident	7 Å²	7	48.9 Å²	48.9	4%	0.042	26%	0.255	C	S	.	.	S	Bend	trans	-66.7	121.3	178.1	176.2	0	0	0	0	109.5	K319 I320 L358 D359 L363 I369	K319-V361 HydrophobicContact CB-CG2 4.3Å; I320-V361 HydrophobicContact CD1-CG1 4.12Å; I320-V361 HydrophobicContact CG1-CG1 4.21Å; I320-V361 HydrophobicContact CG1-CG2 4.12Å; L358-V361 VanDerWaalsContact O-CB 3.29Å; L358-V361 WeakPolarHBondContact O-CB 3.45Å; L358-V361 WeakPolarHBondContact O-CG2 3.48Å; L358-V361 PolarHBondContact O-N 3.13Å; L358-V361 VanDerWaalsContact O-N 3.07Å; D359-V361 VanDerWaalsContact C-N 3.29Å; D359-V361 PolarHBondContact O-N 3.01Å; V361-L363 PolarHBondContact O-N 3.28Å; V361-I369 HydrophobicContact CG1-CG2 4.44Å
362	S	83.7	Confident	86.3	Confident	65 Å²	65	48.9 Å²	48.9	46%	0.455	26%	0.255	S	S	.	.			trans	-60.1	108	170.1	-179.1	0	0	0	0	108.8	S316 E360 E364	S316-S362 WeakPolarHBondContact CB-O 3.03Å; S316-S362 PolarHBondContact OG-O 3.05Å; E360-S362 PolarHBondContact O-N 3.21Å; S362-E364 PolarHBondContact O-N 3.25Å; S362-E364 WeakPolarHBondContact OG-CG 3.45Å
363	L	72.8	Confident	86	Confident	44 Å²	44	47.6 Å²	47.6	23%	0.23	25%	0.247	C	C	.	.			trans	-64.6	-22.7	175.3	-68.5	-177.4	0	0	0	112.5	V361 R370 R373	V361-L363 PolarHBondContact O-N 3.28Å; L363-R370 HydrophobicContact CB-CG 3.98Å; L363-R370 HydrophobicContact CD1-CG 4.04Å; L363-R370 HydrophobicContact CD2-CB 4.38Å; L363-R370 HydrophobicContact CD2-CG 3.96Å; L363-R370 HydrophobicContact CG-CG 4.22Å; L363-R373 VanDerWaalsContact CD1-NH1 3.31Å; L363-R373 HydrophobicContact CD2-CB 4.17Å; L363-R373 VanDerWaalsContact CD2-NH1 3.32Å; L363-R373 VanDerWaalsContact CG-NH1 3.31Å
364	E	68.2	Low	85.7	Confident	110 Å²	110	50.6 Å²	50.6	51%	0.514	25%	0.246	S	C	.	.	T	Hydrogen-bonded Turn	trans	46.3	-160.6	-163.5	-61.7	177.7	173.7	0	0	109.6	S362	S362-E364 PolarHBondContact O-N 3.25Å; S362-E364 WeakPolarHBondContact OG-CG 3.45Å
365	K	68.2	Low	85.3	Confident	137 Å²	137	51 Å²	51	60%	0.596	25%	0.247	S	C	*	.	T	Hydrogen-bonded Turn	trans	-95	25.7	171.4	-51.9	-159.7	-167.8	170.7	0	111.9	E202 P367	E202-K365 WeakPolarHBondContact OE1-CD 3.4Å; E202-K365 IonicContact OE1-NZ 3.01Å; E202-K365 VanDerWaalsContact OE2-CD 3.31Å; E202-K365 WeakPolarHBondContact OE2-CD 3.38Å; E202-K365 IonicContact OE2-NZ 2.77Å; E202-K365 PolarHBondContact OE2-NZ 3.44Å; K365-P367 WeakPolarHBondContact O-CD 3.13Å
366	N	72.4	Confident	85.2	Confident	17 Å²	17	50 Å²	50	9%	0.091	24%	0.242	C	C	.	.			trans	-99.8	110.9	-174.4	-169.7	-37.8	0	0	0	110.9	C368 I369 R370	N366-C368 PolarHBondContact O-N 3.28Å; N366-C368 VanDerWaalsContact OD1-CB 3.31Å; N366-C368 WeakPolarHBondContact OD1-CB 3.42Å; N366-C368 PolarHBondContact OD1-N 2.68Å; N366-I369 HydrophobicContact CB-CB 4.31Å; N366-I369 HydrophobicContact CB-CD1 3.78Å; N366-I369 HydrophobicContact CB-CG1 3.89Å; N366-I369 PolarHBondContact O-N 3.01Å; N366-I369 VanDerWaalsContact O-N 3.1Å; N366-R370 PolarHBondContact O-N 3.08Å
367	P	75.2	Confident	85.1	Confident	9 Å²	9	50.5 Å²	50.5	6%	0.058	24%	0.239	C	C	.	.	H	α-helix	trans	-57.3	-32.9	-179.3	-24.4	34.3	0	0	0	113.9	I172 T176 L194 C198 K365 I369 R370 E371	I172-P367 HydrophobicContact CG2-CB 3.92Å; I172-P367 HydrophobicContact CG2-CG 4.19Å; T176-P367 HydrophobicContact CG2-CB 3.72Å; L194-P367 HydrophobicContact CB-CG 4.4Å; L194-P367 HydrophobicContact CD1-CB 4.45Å; L194-P367 HydrophobicContact CD2-CB 4.22Å; L194-P367 HydrophobicContact CD2-CG 4.21Å; C198-P367 WeakPolarHBondContact SG-CG 3.44Å; K365-P367 WeakPolarHBondContact O-CD 3.13Å; P367-I369 PolarHBondContact O-N 3.03Å; P367-R370 WeakPolarHBondContact O-CB 3.43Å; P367-R370 PolarHBondContact O-N 3.04Å; P367-E371 PolarHBondContact O-N 3.33Å
368	C	78.9	Confident	85	Confident	3 Å²	3	48.4 Å²	48.4	2%	0.02	23%	0.23	C	C	.	.	H	α-helix	trans	-67.6	-35.6	179.4	-59.6	0	0	0	0	111.9	L311 N366 E371 A372	L311-C368 HydrophobicContact CD1-CB 3.47Å; L311-C368 VanDerWaalsContact CD1-CB 3.47Å; N366-C368 PolarHBondContact O-N 3.28Å; N366-C368 VanDerWaalsContact OD1-CB 3.31Å; N366-C368 WeakPolarHBondContact OD1-CB 3.42Å; N366-C368 PolarHBondContact OD1-N 2.68Å; C368-E371 PolarHBondContact O-N 2.79Å; C368-A372 VanDerWaalsContact O-CB 3.27Å; C368-A372 WeakPolarHBondContact O-CB 3.4Å; C368-A372 PolarHBondContact O-N 2.94Å
369	I	82.7	Confident	84.9	Confident	0 Å²	0	50.5 Å²	50.5	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-70.6	-36.9	175.5	-58.2	178.1	0	0	0	110.4	L311 I317 I320 V361 N366 P367 A372 R373	L311-I369 HydrophobicContact CD2-CG1 4.47Å; I317-I369 HydrophobicContact CD1-CB 4.36Å; I317-I369 HydrophobicContact CD1-CG1 3.92Å; I317-I369 HydrophobicContact CD1-CG2 4.4Å; I317-I369 HydrophobicContact CG1-CG1 4.29Å; I320-I369 HydrophobicContact CD1-CG2 4.49Å; V361-I369 HydrophobicContact CG1-CG2 4.44Å; N366-I369 HydrophobicContact CB-CB 4.31Å; N366-I369 HydrophobicContact CB-CD1 3.78Å; N366-I369 HydrophobicContact CB-CG1 3.89Å; N366-I369 PolarHBondContact O-N 3.01Å; N366-I369 VanDerWaalsContact O-N 3.1Å; P367-I369 PolarHBondContact O-N 3.03Å; I369-A372 WeakPolarHBondContact O-CB 3.48Å; I369-A372 PolarHBondContact O-N 3.13Å; I369-R373 WeakPolarHBondContact O-CB 3.41Å; I369-R373 PolarHBondContact O-N 3.24Å
370	R	84.5	Confident	85	Confident	81 Å²	81	45.6 Å²	45.6	31%	0.306	21%	0.214	S	C	.	.	H	α-helix	trans	-61.6	-46.6	173.7	-62.6	-165.8	-63.5	-112.3	5.8	111.6	L363 N366 P367 R373 R374	L363-R370 HydrophobicContact CB-CG 3.98Å; L363-R370 HydrophobicContact CD1-CG 4.04Å; L363-R370 HydrophobicContact CD2-CB 4.38Å; L363-R370 HydrophobicContact CD2-CG 3.96Å; L363-R370 HydrophobicContact CG-CG 4.22Å; N366-R370 PolarHBondContact O-N 3.08Å; P367-R370 WeakPolarHBondContact O-CB 3.43Å; P367-R370 PolarHBondContact O-N 3.04Å; R370-R373 PolarHBondContact O-N 2.87Å; R370-R374 WeakPolarHBondContact O-CB 3.49Å; R370-R374 PolarHBondContact O-N 3.22Å
371	E	84.8	Confident	85.2	Confident	10 Å²	10	41.4 Å²	41.4	5%	0.047	19%	0.194	C	C	.	.	H	α-helix	trans	-66.9	-42.2	178.8	-179.9	58.7	-171.2	0	0	111.8	H177 P367 C368 R373 R374 R375 W486	H177-E371 IonicContact CD2-OE1 2.65Å; H177-E371 IonicContact NE2-OE1 3.69Å; H177-E371 PolarHBondContact NE2-OE1 3.38Å; P367-E371 PolarHBondContact O-N 3.33Å; C368-E371 PolarHBondContact O-N 2.79Å; E371-R373 VanDerWaalsContact C-N 3.34Å; E371-R373 PolarHBondContact O-N 3Å; E371-R374 PolarHBondContact O-N 3.48Å; E371-R374 IonicContact OE1-CZ 2.98Å; E371-R374 IonicContact OE1-NE 3.77Å; E371-R374 IonicContact OE1-NH2 3.91Å; E371-R374 PolarHBondContact OE1-NH2 3.45Å; E371-R374 IonicContact OE2-CZ 3.8Å; E371-R374 IonicContact OE2-NE 2.68Å; E371-R374 PolarHBondContact OE2-NE 3.08Å; E371-R374 IonicContact OE2-NH2 2.79Å; E371-R374 PolarHBondContact OE2-NH2 3.24Å; E371-R375 WeakPolarHBondContact O-CG 3.46Å; E371-R375 PolarHBondContact O-N 3.44Å; E371-R375 IonicContact OE1-CZ 2.74Å; E371-R375 IonicContact OE1-NE 3.29Å; E371-R375 PolarHBondContact OE1-NE 3.45Å; E371-R375 IonicContact OE1-NH2 2.81Å; E371-W486 HydrophobicContact CG-CZ2 4.35Å
372	A	87.4	Confident	85.4	Confident	1 Å²	1	41.8 Å²	41.8	1%	0.008	20%	0.197	C	C	.	.	H	α-helix	trans	-49.8	-54.4	170.9	0	0	0	0	0	112	I317 I320 C368 I369 R374 R375 A376 W486 Y488	I317-A372 HydrophobicContact CD1-CB 3.75Å; I320-A372 HydrophobicContact CD1-CB 3.64Å; C368-A372 VanDerWaalsContact O-CB 3.27Å; C368-A372 WeakPolarHBondContact O-CB 3.4Å; C368-A372 PolarHBondContact O-N 2.94Å; I369-A372 WeakPolarHBondContact O-CB 3.48Å; I369-A372 PolarHBondContact O-N 3.13Å; A372-R374 VanDerWaalsContact C-N 3.35Å; A372-R374 PolarHBondContact O-N 3.21Å; A372-R375 PolarHBondContact O-N 3.12Å; A372-A376 WeakPolarHBondContact O-CB 3.34Å; A372-A376 PolarHBondContact O-N 3.44Å; A372-W486 VanDerWaalsContact CA-CH2 3.46Å; A372-W486 HydrophobicContact CB-CH2 3.55Å; A372-W486 HydrophobicContact CB-CZ2 4.35Å; A372-W486 HydrophobicContact CB-CZ3 4.31Å; A372-Y488 HydrophobicContact CB-CD1 4.27Å; A372-Y488 HydrophobicContact CB-CE1 3.57Å
373	R	91.9	Very high	86	Confident	66 Å²	66	38.8 Å²	38.8	25%	0.249	18%	0.176	C	C	.	.	H	α-helix	trans	-63	-44.5	-179.1	-172	-164.8	67.5	-179.3	5.5	110.3	I320 L358 L363 I369 R370 E371 R375 A376 V377	I320-R373 HydrophobicContact CD1-CB 4.03Å; L358-R373 HydrophobicContact CB-CG 4.26Å; L358-R373 HydrophobicContact CD2-CG 4.42Å; L358-R373 WeakPolarHBondContact O-CD 3.34Å; L363-R373 VanDerWaalsContact CD1-NH1 3.31Å; L363-R373 HydrophobicContact CD2-CB 4.17Å; L363-R373 VanDerWaalsContact CD2-NH1 3.32Å; L363-R373 VanDerWaalsContact CG-NH1 3.31Å; I369-R373 WeakPolarHBondContact O-CB 3.41Å; I369-R373 PolarHBondContact O-N 3.24Å; R370-R373 PolarHBondContact O-N 2.87Å; E371-R373 VanDerWaalsContact C-N 3.34Å; E371-R373 PolarHBondContact O-N 3Å; R373-R375 PolarHBondContact O-N 3.42Å; R373-A376 PolarHBondContact O-N 3.3Å; R373-V377 HydrophobicContact CG-CG2 4.37Å; R373-V377 WeakPolarHBondContact O-CB 3.14Å; R373-V377 VanDerWaalsContact O-CG2 3.32Å; R373-V377 WeakPolarHBondContact O-CG2 3.39Å; R373-V377 PolarHBondContact O-N 3.23Å
374	R	90.3	Very high	87.1	Confident	100 Å²	100	36.7 Å²	36.7	38%	0.377	17%	0.165	S	C	.	.	H	α-helix	trans	-57.7	-47.7	178.6	-170.7	-166.4	70.3	85	5.4	111.2	R370 E371 A372 V377 I378	R370-R374 WeakPolarHBondContact O-CB 3.49Å; R370-R374 PolarHBondContact O-N 3.22Å; E371-R374 PolarHBondContact O-N 3.48Å; E371-R374 IonicContact OE1-CZ 2.98Å; E371-R374 IonicContact OE1-NE 3.77Å; E371-R374 IonicContact OE1-NH2 3.91Å; E371-R374 PolarHBondContact OE1-NH2 3.45Å; E371-R374 IonicContact OE2-CZ 3.8Å; E371-R374 IonicContact OE2-NE 2.68Å; E371-R374 PolarHBondContact OE2-NE 3.08Å; E371-R374 IonicContact OE2-NH2 2.79Å; E371-R374 PolarHBondContact OE2-NH2 3.24Å; A372-R374 VanDerWaalsContact C-N 3.35Å; A372-R374 PolarHBondContact O-N 3.21Å; R374-V377 PolarHBondContact O-N 3.38Å; R374-I378 HydrophobicContact CG-CD1 4.2Å; R374-I378 WeakPolarHBondContact O-CG1 3.5Å; R374-I378 PolarHBondContact O-N 2.86Å
375	R	89.8	Confident	88.3	Confident	15 Å²	15	33.4 Å²	33.4	6%	0.057	15%	0.152	C	C	.	.	H	α-helix	trans	-60.8	-45.1	176.8	-70.7	-176.7	175.1	-124.6	4.1	111.5	H177 E371 A372 R373 V377 I378 E379 L481 D484 W486	H177-R375 PolarHBondContact CD2-NH2 3.32Å; H177-R375 VanDerWaalsContact CD2-NH2 3.34Å; E371-R375 WeakPolarHBondContact O-CG 3.46Å; E371-R375 PolarHBondContact O-N 3.44Å; E371-R375 IonicContact OE1-CZ 2.74Å; E371-R375 IonicContact OE1-NE 3.29Å; E371-R375 PolarHBondContact OE1-NE 3.45Å; E371-R375 IonicContact OE1-NH2 2.81Å; A372-R375 PolarHBondContact O-N 3.12Å; R373-R375 PolarHBondContact O-N 3.42Å; R375-V377 PolarHBondContact O-N 2.86Å; R375-I378 PolarHBondContact O-N 3.49Å; R375-E379 PolarHBondContact O-N 2.98Å; R375-L481 HydrophobicContact CG-CD1 4.13Å; R375-L481 HydrophobicContact CG-CD2 4.5Å; R375-L481 HydrophobicContact CG-CG 4.46Å; R375-D484 IonicContact CZ-OD2 3.01Å; R375-D484 IonicContact NH1-OD2 3.2Å; R375-D484 PolarHBondContact NH1-OD2 3.11Å; R375-D484 IonicContact NH2-OD2 2.69Å; R375-D484 PolarHBondContact NH2-OD2 3.02Å; R375-W486 VanDerWaalsContact CZ-CB 3.42Å
376	A	93.6	Very high	89.6	Confident	0 Å²	0	28 Å²	28	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-63.1	-41.2	177.2	0	0	0	0	0	113.2	I320 L324 L358 A372 R373 I378 E379 V380	I320-A376 HydrophobicContact CG2-CB 3.67Å; L324-A376 HydrophobicContact CD1-CB 4.29Å; L324-A376 HydrophobicContact CD2-CB 3.78Å; L324-A376 HydrophobicContact CG-CB 4.02Å; L358-A376 HydrophobicContact CD1-CB 4.03Å; L358-A376 HydrophobicContact CD2-CB 3.89Å; A372-A376 WeakPolarHBondContact O-CB 3.34Å; A372-A376 PolarHBondContact O-N 3.44Å; R373-A376 PolarHBondContact O-N 3.3Å; A376-I378 VanDerWaalsContact C-N 3.33Å; A376-I378 PolarHBondContact O-N 2.83Å; A376-E379 PolarHBondContact O-N 3.48Å; A376-V380 WeakPolarHBondContact O-CG2 3.05Å; A376-V380 PolarHBondContact O-N 3.34Å
377	V	95	Very high	90.7	Very high	39 Å²	39	27.2 Å²	27.2	24%	0.236	12%	0.124	C	C	.	.	H	α-helix	trans	-60.3	-44.5	173.7	166.9	0	0	0	0	110.4	I355 L358 R373 R374 R375 E379 V380 Q381	I355-V377 HydrophobicContact CD1-CB 4.49Å; I355-V377 HydrophobicContact CD1-CG1 4.16Å; I355-V377 HydrophobicContact CD1-CG2 4.5Å; L358-V377 HydrophobicContact CB-CG2 3.94Å; L358-V377 HydrophobicContact CD1-CB 4.48Å; L358-V377 HydrophobicContact CD1-CG2 3.74Å; L358-V377 HydrophobicContact CG-CG2 4.43Å; R373-V377 HydrophobicContact CG-CG2 4.37Å; R373-V377 WeakPolarHBondContact O-CB 3.14Å; R373-V377 VanDerWaalsContact O-CG2 3.32Å; R373-V377 WeakPolarHBondContact O-CG2 3.39Å; R373-V377 PolarHBondContact O-N 3.23Å; R374-V377 PolarHBondContact O-N 3.38Å; R375-V377 PolarHBondContact O-N 2.86Å; V377-E379 PolarHBondContact O-N 3.5Å; V377-V380 PolarHBondContact O-N 3.46Å; V377-Q381 WeakPolarHBondContact O-CB 3.14Å; V377-Q381 PolarHBondContact O-N 2.73Å
378	I	93.1	Very high	91.6	Very high	48 Å²	48	29.5 Å²	29.5	25%	0.246	14%	0.136	C	C	.	.	H	α-helix	trans	-62.9	-41.7	177.6	-70.3	166.7	0	0	0	111.5	R374 R375 A376 Q381 T382 Y478 L481	R374-I378 HydrophobicContact CG-CD1 4.2Å; R374-I378 WeakPolarHBondContact O-CG1 3.5Å; R374-I378 PolarHBondContact O-N 2.86Å; R375-I378 PolarHBondContact O-N 3.49Å; A376-I378 VanDerWaalsContact C-N 3.33Å; A376-I378 PolarHBondContact O-N 2.83Å; I378-Q381 PolarHBondContact O-N 3.16Å; I378-T382 VanDerWaalsContact O-CB 3.31Å; I378-T382 WeakPolarHBondContact O-CB 3.31Å; I378-T382 PolarHBondContact O-N 3.02Å; I378-T382 PolarHBondContact O-OG1 3.03Å; I378-Y478 HydrophobicContact CG2-CD2 4.01Å; I378-L481 HydrophobicContact CB-CD1 4.41Å; I378-L481 HydrophobicContact CD1-CD1 3.9Å; I378-L481 HydrophobicContact CG2-CD1 4.1Å
379	E	93.5	Very high	92.3	Very high	44 Å²	44	30 Å²	30	21%	0.206	14%	0.138	C	C	.	.	H	α-helix	trans	-61	-50.2	176.5	-80	-173.5	-131.1	0	0	112.1	L324 M327 R375 A376 V377 T382 L383 Y478	L324-E379 HydrophobicContact CD2-CB 4.24Å; M327-E379 HydrophobicContact CE-CB 3.65Å; M327-E379 HydrophobicContact CE-CG 4.37Å; M327-E379 WeakPolarHBondContact CE-OE2 3.37Å; R375-E379 PolarHBondContact O-N 2.98Å; A376-E379 PolarHBondContact O-N 3.48Å; V377-E379 PolarHBondContact O-N 3.5Å; E379-T382 PolarHBondContact O-N 2.71Å; E379-L383 PolarHBondContact O-N 2.85Å; E379-Y478 HydrophobicContact CB-CE2 4.4Å; E379-Y478 HydrophobicContact CG-CE2 3.78Å
380	V	96.7	Very high	92.7	Very high	0 Å²	0	32 Å²	32	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-63	-45.1	178.5	176.3	0	0	0	0	110.6	V323 M327 L351 L354 I355 L358 A376 V377 T382 L383 I384	V323-V380 HydrophobicContact CG1-CG2 4.25Å; M327-V380 HydrophobicContact CB-CG2 4.17Å; M327-V380 HydrophobicContact CG-CG2 3.92Å; L351-V380 HydrophobicContact CB-CG1 4.1Å; L351-V380 HydrophobicContact CD2-CG1 3.99Å; L351-V380 WeakPolarHBondContact O-CG1 3.48Å; L354-V380 HydrophobicContact CB-CG1 4.37Å; I355-V380 HydrophobicContact CD1-CB 3.66Å; I355-V380 HydrophobicContact CD1-CG1 3.49Å; I355-V380 VanDerWaalsContact CD1-CG1 3.49Å; I355-V380 HydrophobicContact CG1-CB 4.44Å; I355-V380 HydrophobicContact CG1-CG1 3.71Å; L358-V380 HydrophobicContact CD1-CG2 4.18Å; A376-V380 WeakPolarHBondContact O-CG2 3.05Å; A376-V380 PolarHBondContact O-N 3.34Å; V377-V380 PolarHBondContact O-N 3.46Å; V380-T382 VanDerWaalsContact C-N 3.34Å; V380-T382 PolarHBondContact O-N 3.35Å; V380-L383 PolarHBondContact O-N 3.43Å; V380-I384 HydrophobicContact CG1-CD1 4.21Å; V380-I384 WeakPolarHBondContact O-CG1 3.43Å; V380-I384 PolarHBondContact O-N 2.89Å
381	Q	96.3	Very high	93.1	Very high	73 Å²	73	30 Å²	30	34%	0.341	14%	0.141	S	C	.	.	H	α-helix	trans	-65	-37.6	-179.7	-171.3	59.9	67.1	0	0	111.9	V377 I378 L383 I384 T385	V377-Q381 WeakPolarHBondContact O-CB 3.14Å; V377-Q381 PolarHBondContact O-N 2.73Å; I378-Q381 PolarHBondContact O-N 3.16Å; Q381-L383 VanDerWaalsContact C-N 3.31Å; Q381-L383 PolarHBondContact O-N 2.89Å; Q381-I384 WeakPolarHBondContact O-CB 3.4Å; Q381-I384 PolarHBondContact O-N 3.07Å; Q381-T385 WeakPolarHBondContact O-CG2 3.47Å; Q381-T385 PolarHBondContact O-N 3.03Å; Q381-T385 PolarHBondContact O-OG1 3.35Å
382	T	94.9	Very high	93.3	Very high	16 Å²	16	31.2 Å²	31.2	10%	0.098	15%	0.153	C	C	.	.	H	α-helix	trans	-59.8	-43.3	174.7	-61.7	0	0	0	0	110.9	I378 E379 V380 I384 T385 Y386 Q421 L425 Y478	I378-T382 VanDerWaalsContact O-CB 3.31Å; I378-T382 WeakPolarHBondContact O-CB 3.31Å; I378-T382 PolarHBondContact O-N 3.02Å; I378-T382 PolarHBondContact O-OG1 3.03Å; E379-T382 PolarHBondContact O-N 2.71Å; V380-T382 VanDerWaalsContact C-N 3.34Å; V380-T382 PolarHBondContact O-N 3.35Å; T382-I384 PolarHBondContact O-N 2.9Å; T382-T385 WeakPolarHBondContact CA-OG1 3.32Å; T382-T385 PolarHBondContact O-N 3.29Å; T382-T385 PolarHBondContact O-OG1 3.28Å; T382-Y386 PolarHBondContact O-N 2.81Å; T382-Q421 PolarHBondContact O-NE2 3.38Å; T382-L425 HydrophobicContact CG2-CD2 4.23Å; T382-Y478 HydrophobicContact CG2-CD1 3.64Å; T382-Y478 HydrophobicContact CG2-CD2 4.3Å; T382-Y478 HydrophobicContact CG2-CE1 3.81Å; T382-Y478 HydrophobicContact CG2-CE2 4.47Å; T382-Y478 HydrophobicContact CG2-CG 3.88Å; T382-Y478 WeakPolarHBondContact OG1-CD2 3.47Å
383	L	95.6	Very high	93.5	Very high	1 Å²	1	32.2 Å²	32.2	1%	0.005	16%	0.158	C	C	.	.	H	α-helix	trans	-65.9	-37.9	177.2	-171.8	58.3	0	0	0	112.4	M327 I330 K331 L334 L351 E379 V380 Q381 Y386 I387 L425	M327-L383 HydrophobicContact CG-CD2 4.11Å; M327-L383 HydrophobicContact SD-CD2 4Å; I330-L383 HydrophobicContact CG2-CD2 4.38Å; K331-L383 HydrophobicContact CB-CD1 4.46Å; K331-L383 HydrophobicContact CB-CD2 3.84Å; K331-L383 HydrophobicContact CG-CD1 4.22Å; K331-L383 HydrophobicContact CG-CD2 4.42Å; L334-L383 HydrophobicContact CD1-CD1 4.13Å; L334-L383 HydrophobicContact CD1-CD2 4.42Å; L334-L383 HydrophobicContact CD1-CG 4.35Å; L351-L383 HydrophobicContact CD1-CB 4.21Å; L351-L383 HydrophobicContact CD1-CD2 3.83Å; L351-L383 HydrophobicContact CD1-CG 3.76Å; L351-L383 HydrophobicContact CD2-CD2 3.8Å; L351-L383 HydrophobicContact CD2-CG 4.46Å; L351-L383 HydrophobicContact CG-CD2 4.46Å; E379-L383 PolarHBondContact O-N 2.85Å; V380-L383 PolarHBondContact O-N 3.43Å; Q381-L383 VanDerWaalsContact C-N 3.31Å; Q381-L383 PolarHBondContact O-N 2.89Å; L383-Y386 HydrophobicContact CD1-CD1 4.24Å; L383-Y386 WeakPolarHBondContact O-CB 3.39Å; L383-Y386 PolarHBondContact O-N 2.91Å; L383-I387 WeakPolarHBondContact O-CG1 3.32Å; L383-I387 PolarHBondContact O-N 3.41Å; L383-I387 VanDerWaalsContact O-N 3.11Å; L383-L425 HydrophobicContact CD1-CD1 3.97Å; L383-L425 HydrophobicContact CD1-CD2 4.37Å
384	I	96	Very high	93.3	Very high	1 Å²	1	32 Å²	32	1%	0.005	16%	0.16	C	C	.	.	H	α-helix	trans	-60.2	-47.3	172.1	-66.2	167.8	0	0	0	110.6	K348 L351 Q352 I355 V380 Q381 T382 Y386 I387 D388	K348-I384 HydrophobicContact CG-CG2 4.38Å; L351-I384 HydrophobicContact CB-CD1 3.87Å; L351-I384 HydrophobicContact CB-CG1 3.59Å; L351-I384 HydrophobicContact CD1-CG1 3.99Å; L351-I384 HydrophobicContact CG-CG1 4.39Å; Q352-I384 HydrophobicContact CG-CD1 4.27Å; I355-I384 HydrophobicContact CG1-CD1 4.28Å; V380-I384 HydrophobicContact CG1-CD1 4.21Å; V380-I384 WeakPolarHBondContact O-CG1 3.43Å; V380-I384 PolarHBondContact O-N 2.89Å; Q381-I384 WeakPolarHBondContact O-CB 3.4Å; Q381-I384 PolarHBondContact O-N 3.07Å; T382-I384 PolarHBondContact O-N 2.9Å; I384-Y386 VanDerWaalsContact C-N 3.26Å; I384-Y386 PolarHBondContact O-N 3.43Å; I384-I387 PolarHBondContact O-N 3.23Å; I384-I387 VanDerWaalsContact O-N 3.15Å; I384-D388 PolarHBondContact O-N 3.31Å
385	T	94.7	Very high	93.1	Very high	41 Å²	41	32.9 Å²	32.9	25%	0.252	17%	0.166	S	C	.	.	H	α-helix	trans	-63.6	-32.9	179.5	61.2	0	0	0	0	112.7	Q381 T382 D388 L389 Q421	Q381-T385 WeakPolarHBondContact O-CG2 3.47Å; Q381-T385 PolarHBondContact O-N 3.03Å; Q381-T385 PolarHBondContact O-OG1 3.35Å; T382-T385 WeakPolarHBondContact CA-OG1 3.32Å; T382-T385 PolarHBondContact O-N 3.29Å; T382-T385 PolarHBondContact O-OG1 3.28Å; T385-D388 PolarHBondContact O-N 3.03Å; T385-L389 WeakPolarHBondContact O-CB 3.46Å; T385-L389 PolarHBondContact O-N 3.35Å; T385-Q421 PolarHBondContact OG1-NE2 2.65Å
386	Y	95.2	Very high	92.9	Very high	23 Å²	23	35.3 Å²	35.3	9%	0.09	18%	0.175	C	C	.	.	H	α-helix	trans	-63.6	-45.2	173.7	172.7	-101.6	0	0	0	111.5	L335 T382 L383 I384 L389 K390 S418 Q421 L425	L335-Y386 HydrophobicContact CD2-CE1 4.42Å; T382-Y386 PolarHBondContact O-N 2.81Å; L383-Y386 HydrophobicContact CD1-CD1 4.24Å; L383-Y386 WeakPolarHBondContact O-CB 3.39Å; L383-Y386 PolarHBondContact O-N 2.91Å; I384-Y386 VanDerWaalsContact C-N 3.26Å; I384-Y386 PolarHBondContact O-N 3.43Å; Y386-L389 PolarHBondContact O-N 2.97Å; Y386-K390 HydrophobicContact CE1-CG 4.17Å; Y386-K390 HydrophobicContact CE2-CG 4.28Å; Y386-K390 WeakPolarHBondContact O-CG 3.31Å; Y386-K390 PolarHBondContact O-N 2.8Å; Y386-K390 WeakPolarHBondContact OH-CE 3.28Å; Y386-S418 WeakPolarHBondContact CE2-O 3.46Å; Y386-Q421 HydrophobicContact CD2-CB 4.12Å; Y386-Q421 HydrophobicContact CD2-CG 3.9Å; Y386-L425 HydrophobicContact CD1-CD1 3.89Å; Y386-L425 HydrophobicContact CD2-CD1 3.83Å; Y386-L425 HydrophobicContact CE1-CD1 4.38Å; Y386-L425 HydrophobicContact CE2-CD1 4.29Å; Y386-L425 HydrophobicContact CG-CD1 3.59Å
387	I	94.4	Very high	92.4	Very high	0 Å²	0	42.3 Å²	42.3	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-61.7	-47.7	175.8	-64.5	167.7	0	0	0	110.3	L334 Y344 K348 L351 L383 I384 L389 K390 E391	L334-I387 HydrophobicContact CD1-CD1 3.71Å; L334-I387 HydrophobicContact CD1-CG1 4.01Å; Y344-I387 HydrophobicContact CD1-CG2 4.01Å; Y344-I387 HydrophobicContact CG-CG2 3.84Å; K348-I387 HydrophobicContact CB-CD1 4.34Å; K348-I387 HydrophobicContact CB-CG2 4.37Å; L351-I387 HydrophobicContact CD1-CD1 3.62Å; L383-I387 WeakPolarHBondContact O-CG1 3.32Å; L383-I387 PolarHBondContact O-N 3.41Å; L383-I387 VanDerWaalsContact O-N 3.11Å; I384-I387 PolarHBondContact O-N 3.23Å; I384-I387 VanDerWaalsContact O-N 3.15Å; I387-L389 VanDerWaalsContact C-N 3.28Å; I387-L389 PolarHBondContact O-N 3.38Å; I387-K390 PolarHBondContact O-N 3Å; I387-K390 VanDerWaalsContact O-N 3.14Å; I387-E391 HydrophobicContact CG2-CG 4.37Å; I387-E391 PolarHBondContact O-N 2.89Å
388	D	94.1	Very high	91.7	Very high	57 Å²	57	46.8 Å²	46.8	31%	0.305	23%	0.228	S	C	.	.	H	α-helix	trans	-57.7	-42.1	179.4	-72.1	-20.4	0	0	0	112.2	K348 I384 T385 A392	K348-D388 WeakPolarHBondContact CE-OD1 3.46Å; K348-D388 IonicContact NZ-OD1 3.82Å; K348-D388 PolarHBondContact NZ-OD1 2.77Å; K348-D388 IonicContact NZ-OD2 2.98Å; I384-D388 PolarHBondContact O-N 3.31Å; T385-D388 PolarHBondContact O-N 3.03Å; D388-A392 WeakPolarHBondContact O-CB 3.32Å; D388-A392 PolarHBondContact O-N 2.95Å
389	L	93.5	Very high	90.5	Very high	14 Å²	14	52.4 Å²	52.4	7%	0.073	25%	0.251	C	S	.	.	H	α-helix	trans	-65.5	-45.3	176.6	-179.4	62.6	0	0	0	111.7	T385 Y386 I387 A392 L393 L414 L471	T385-L389 WeakPolarHBondContact O-CB 3.46Å; T385-L389 PolarHBondContact O-N 3.35Å; Y386-L389 PolarHBondContact O-N 2.97Å; I387-L389 VanDerWaalsContact C-N 3.28Å; I387-L389 PolarHBondContact O-N 3.38Å; L389-A392 PolarHBondContact O-N 2.65Å; L389-L393 HydrophobicContact CD1-CD1 4.34Å; L389-L393 HydrophobicContact CD1-CG 4.46Å; L389-L393 HydrophobicContact CG-CD1 4.14Å; L389-L393 VanDerWaalsContact O-CG 3.29Å; L389-L393 WeakPolarHBondContact O-CG 3.38Å; L389-L393 PolarHBondContact O-N 3.37Å; L389-L414 HydrophobicContact CD1-CB 4.13Å; L389-L414 HydrophobicContact CD1-CD2 4.03Å; L389-L471 HydrophobicContact CD1-CD2 4.04Å; L389-L471 HydrophobicContact CD2-CD2 3.78Å; L389-L471 HydrophobicContact CG-CD2 4.47Å
390	K	91.9	Very high	89.1	Confident	41 Å²	41	54.8 Å²	54.8	18%	0.178	28%	0.278	C	S	.	.	H	α-helix	trans	-60.6	-45.8	175.9	-75.3	-66.8	-171.9	-158.4	0	111.4	Y344 Y386 I387 A392 L393 E394 S418	Y344-K390 HydrophobicContact CE1-CB 4.38Å; Y344-K390 HydrophobicContact CE2-CB 3.84Å; Y344-K390 WeakPolarHBondContact OH-CB 3.37Å; Y386-K390 HydrophobicContact CE1-CG 4.17Å; Y386-K390 HydrophobicContact CE2-CG 4.28Å; Y386-K390 WeakPolarHBondContact O-CG 3.31Å; Y386-K390 PolarHBondContact O-N 2.8Å; Y386-K390 WeakPolarHBondContact OH-CE 3.28Å; I387-K390 PolarHBondContact O-N 3Å; I387-K390 VanDerWaalsContact O-N 3.14Å; K390-A392 VanDerWaalsContact C-N 3.34Å; K390-A392 PolarHBondContact O-N 3.47Å; K390-L393 PolarHBondContact O-N 2.81Å; K390-E394 WeakPolarHBondContact O-CG 3.42Å; K390-E394 PolarHBondContact O-N 2.94Å; K390-S418 VanDerWaalsContact CD-OG 3.25Å; K390-S418 WeakPolarHBondContact CD-OG 3.31Å; K390-S418 WeakPolarHBondContact CE-OG 3.36Å; K390-S418 PolarHBondContact NZ-OG 3.42Å
391	E	91.8	Very high	87.3	Confident	39 Å²	39	59.7 Å²	59.7	18%	0.182	31%	0.311	C	S	.	.	H	α-helix	trans	-58.9	-43.8	175.6	-76.6	-171.7	165.7	0	0	112.4	Y344 I387 E394 K395	Y344-E391 WeakPolarHBondContact CB-OE1 3.39Å; Y344-E391 HydrophobicContact CD2-CG 3.57Å; Y344-E391 HydrophobicContact CE2-CG 4.4Å; Y344-E391 HydrophobicContact CG-CG 4.15Å; I387-E391 HydrophobicContact CG2-CG 4.37Å; I387-E391 PolarHBondContact O-N 2.89Å; E391-E394 PolarHBondContact O-N 3.49Å; E391-K395 WeakPolarHBondContact O-CB 3.16Å; E391-K395 VanDerWaalsContact O-CG 3.31Å; E391-K395 WeakPolarHBondContact O-CG 3.5Å; E391-K395 PolarHBondContact O-N 3.17Å; E391-K395 IonicContact OE2-NZ 3.86Å
392	A	90.9	Very high	85.7	Confident	36 Å²	36	65.8 Å²	65.8	30%	0.298	34%	0.34	S	S	.	.	H	α-helix	trans	-63.4	-42.2	178.7	0	0	0	0	0	111.8	D388 L389 K390 R396 W411	D388-A392 WeakPolarHBondContact O-CB 3.32Å; D388-A392 PolarHBondContact O-N 2.95Å; L389-A392 PolarHBondContact O-N 2.65Å; K390-A392 VanDerWaalsContact C-N 3.34Å; K390-A392 PolarHBondContact O-N 3.47Å; A392-R396 PolarHBondContact O-N 3.34Å; A392-W411 HydrophobicContact CB-CH2 4.23Å; A392-W411 HydrophobicContact CB-CZ3 4.29Å
393	L	90.4	Very high	84.5	Confident	22 Å²	22	69.1 Å²	69.1	12%	0.115	35%	0.354	C	S	.	.	H	α-helix	trans	-65.9	-40.1	176.7	-70.2	169.5	0	0	0	112.2	L389 K390 R396 K397 W411 L414	L389-L393 HydrophobicContact CD1-CD1 4.34Å; L389-L393 HydrophobicContact CD1-CG 4.46Å; L389-L393 HydrophobicContact CG-CD1 4.14Å; L389-L393 VanDerWaalsContact O-CG 3.29Å; L389-L393 WeakPolarHBondContact O-CG 3.38Å; L389-L393 PolarHBondContact O-N 3.37Å; K390-L393 PolarHBondContact O-N 2.81Å; L393-R396 WeakPolarHBondContact O-CB 3.4Å; L393-R396 PolarHBondContact O-N 2.98Å; L393-K397 PolarHBondContact O-N 2.88Å; L393-W411 HydrophobicContact CD2-CE3 3.86Å; L393-W411 HydrophobicContact CD2-CZ3 4.02Å; L393-L414 HydrophobicContact CD2-CB 4.42Å
394	E	88.3	Confident	83.7	Confident	61 Å²	61	72.5 Å²	72.5	29%	0.285	37%	0.37	S	S	.	.	H	α-helix	trans	-67.2	-44.6	175.8	-69.1	-50.4	135.7	0	0	112	K390 E391 R396 K397 L398	K390-E394 WeakPolarHBondContact O-CG 3.42Å; K390-E394 PolarHBondContact O-N 2.94Å; E391-E394 PolarHBondContact O-N 3.49Å; E394-R396 PolarHBondContact O-N 3.1Å; E394-K397 WeakPolarHBondContact O-CB 3.48Å; E394-K397 PolarHBondContact O-N 3.41Å; E394-K397 IonicContact OE1-NZ 2.76Å; E394-K397 PolarHBondContact OE1-NZ 3.4Å; E394-K397 WeakPolarHBondContact OE2-CD 3.33Å; E394-K397 IonicContact OE2-NZ 2.71Å; E394-K397 PolarHBondContact OE2-NZ 3.44Å; E394-L398 PolarHBondContact O-N 2.89Å
395	K	86.8	Confident	83.1	Confident	119 Å²	119	76.8 Å²	76.8	52%	0.517	40%	0.398	S	S	.	.	H	α-helix	trans	-56.9	-39.3	173.9	-74.6	169.4	-176.3	163.3	0	111.3	E391 K397 L398 F399	E391-K395 WeakPolarHBondContact O-CB 3.16Å; E391-K395 VanDerWaalsContact O-CG 3.31Å; E391-K395 WeakPolarHBondContact O-CG 3.5Å; E391-K395 PolarHBondContact O-N 3.17Å; E391-K395 IonicContact OE2-NZ 3.86Å; K395-K397 PolarHBondContact O-N 2.99Å; K395-L398 PolarHBondContact O-N 3.31Å; K395-F399 WeakPolarHBondContact O-CD2 3.29Å; K395-F399 PolarHBondContact O-N 2.94Å
396	R	84.4	Confident	82.6	Confident	66 Å²	66	75.2 Å²	75.2	25%	0.249	39%	0.388	C	S	.	.	H	α-helix	trans	-61.5	-42.1	175.7	-172.3	-173.1	-173.8	-142.6	4.4	112.5	A392 L393 E394 L398 F399 A400 E403 W411 D412	A392-R396 PolarHBondContact O-N 3.34Å; L393-R396 WeakPolarHBondContact O-CB 3.4Å; L393-R396 PolarHBondContact O-N 2.98Å; E394-R396 PolarHBondContact O-N 3.1Å; R396-L398 VanDerWaalsContact C-N 3.26Å; R396-L398 PolarHBondContact O-N 2.92Å; R396-F399 PolarHBondContact O-N 3.03Å; R396-A400 PolarHBondContact O-N 3.39Å; R396-E403 IonicContact NE-OE2 3.97Å; R396-E403 IonicContact NH2-OE2 3.51Å; R396-W411 HydrophobicContact CB-CH2 4.36Å; R396-W411 HydrophobicContact CB-CZ3 4.42Å; R396-W411 VanDerWaalsContact CD-CD2 3.46Å; R396-W411 VanDerWaalsContact NE-CG 3.32Å; R396-D412 IonicContact NH1-OD1 3.59Å
397	K	83.5	Confident	82.2	Confident	147 Å²	147	75.3 Å²	75.3	64%	0.639	39%	0.389	S	S	*	.	H	α-helix	trans	-61.2	-35.5	177.5	-68.1	173.1	-173	168.3	0	112.1	L393 E394 K395	L393-K397 PolarHBondContact O-N 2.88Å; E394-K397 WeakPolarHBondContact O-CB 3.48Å; E394-K397 PolarHBondContact O-N 3.41Å; E394-K397 IonicContact OE1-NZ 2.76Å; E394-K397 PolarHBondContact OE1-NZ 3.4Å; E394-K397 WeakPolarHBondContact OE2-CD 3.33Å; E394-K397 IonicContact OE2-NZ 2.71Å; E394-K397 PolarHBondContact OE2-NZ 3.44Å; K395-K397 PolarHBondContact O-N 2.99Å
398	L	79.5	Confident	81.9	Confident	134 Å²	134	81 Å²	81	70%	0.702	41%	0.414	S	S	*	.	H	α-helix	trans	-71.7	-29.8	178.3	-83.4	141.3	0	0	0	113.7	E394 K395 R396	E394-L398 PolarHBondContact O-N 2.89Å; K395-L398 PolarHBondContact O-N 3.31Å; R396-L398 VanDerWaalsContact C-N 3.26Å; R396-L398 PolarHBondContact O-N 2.92Å
399	F	68.7	Low	81.8	Confident	165 Å²	165	80 Å²	80	72%	0.724	41%	0.414	S	S	*	.	T	Hydrogen-bonded Turn	trans	-120.3	34.2	-171.7	-61.6	-68.9	0	0	0	114	K395 R396 C401	K395-F399 WeakPolarHBondContact O-CD2 3.29Å; K395-F399 PolarHBondContact O-N 2.94Å; R396-F399 PolarHBondContact O-N 3.03Å; F399-C401 PolarHBondContact O-N 3.09Å
400	A	63.4	Low	81.7	Confident	94 Å²	94	79.4 Å²	79.4	78%	0.777	41%	0.411	S	S	*	.			trans	-53.4	113.4	-178.1	0	0	0	0	0	112.1	R396	R396-A400 PolarHBondContact O-N 3.39Å
401	C	59.3	Low	81.7	Confident	104 Å²	104	80 Å²	80	70%	0.703	41%	0.412	S	S	*	.			trans	-117.2	160.6	175.4	-167.7	0	0	0	0	109.4	F399 E403	F399-C401 PolarHBondContact O-N 3.09Å; C401-E403 PolarHBondContact O-N 3.31Å
402	E	63.1	Low	81.8	Confident	200 Å²	200	81.9 Å²	81.9	94%	0.935	42%	0.423	S	S	*	.			trans	-67	95.2	171.9	-74.5	-168.2	157.1	0	0	109.9
403	E	69.4	Low	82	Confident	87 Å²	87	80.6 Å²	80.6	41%	0.407	41%	0.412	S	S	.	.			trans	-92.3	152.5	176.4	-67.8	-172.4	160.9	0	0	111.7	R396 C401 H407	R396-E403 IonicContact NE-OE2 3.97Å; R396-E403 IonicContact NH2-OE2 3.51Å; C401-E403 PolarHBondContact O-N 3.31Å; E403-H407 HydrophobicContact CB-CB 4.23Å
404	H	78.8	Confident	82.2	Confident	71 Å²	71	80.7 Å²	80.7	33%	0.329	41%	0.412	S	S	.	.			trans	-55.4	143	172	-166.9	-91.3	0	0	0	111	S406 H407 K408 Q456	H404-S406 PolarHBondContact ND1-N 3.2Å; H404-S406 PolarHBondContact ND1-OG 3.43Å; H404-S406 PolarHBondContact O-N 3.07Å; H404-S406 VanDerWaalsContact O-N 3.11Å; H404-H407 WeakPolarHBondContact O-CB 3.44Å; H404-H407 PolarHBondContact O-N 3.34Å; H404-K408 PolarHBondContact O-N 3.47Å; H404-K408 VanDerWaalsContact O-N 3.09Å; H404-Q456 PolarHBondContact CE1-OE1 3.44Å; H404-Q456 PolarHBondContact NE2-OE1 2.98Å; H404-Q456 VanDerWaalsContact NE2-OE1 3.15Å
405	P	83.6	Confident	82.5	Confident	91 Å²	91	78.8 Å²	78.8	59%	0.591	41%	0.409	S	S	*	.	H	α-helix	trans	-55.1	-33.4	-177.4	18.7	-33.8	0	0	0	114.1	K408 A409	P405-K408 PolarHBondContact O-N 3.43Å; P405-A409 PolarHBondContact O-N 3.49Å
406	S	84.6	Confident	83	Confident	8 Å²	8	76.3 Å²	76.3	6%	0.056	40%	0.401	C	S	.	.	H	α-helix	trans	-67.5	-38.9	176.6	63.1	0	0	0	0	112.8	H404 A409 V410 D454 C461	H404-S406 PolarHBondContact ND1-N 3.2Å; H404-S406 PolarHBondContact ND1-OG 3.43Å; H404-S406 PolarHBondContact O-N 3.07Å; H404-S406 VanDerWaalsContact O-N 3.11Å; S406-A409 PolarHBondContact O-N 3.08Å; S406-V410 WeakPolarHBondContact O-CG2 3.31Å; S406-V410 PolarHBondContact O-N 3.5Å; S406-V410 VanDerWaalsContact O-N 3.16Å; S406-D454 VanDerWaalsContact CB-O 3.28Å; S406-D454 WeakPolarHBondContact CB-O 3.49Å; S406-C461 VanDerWaalsContact CB-SG 3.5Å; S406-C461 PolarHBondContact OG-SG 2.99Å
407	H	85.8	Confident	83.6	Confident	25 Å²	25	73.1 Å²	73.1	12%	0.116	39%	0.389	C	S	.	.	H	α-helix	trans	-64.7	-43.3	173.4	-96.4	-80.7	0	0	0	111.3	E403 H404 A409 V410 W411 E458 C461	E403-H407 HydrophobicContact CB-CB 4.23Å; H404-H407 WeakPolarHBondContact O-CB 3.44Å; H404-H407 PolarHBondContact O-N 3.34Å; H407-A409 VanDerWaalsContact C-N 3.34Å; H407-A409 PolarHBondContact O-N 2.96Å; H407-V410 PolarHBondContact O-N 3.23Å; H407-W411 PolarHBondContact O-N 3.31Å; H407-W411 VanDerWaalsContact O-N 3.14Å; H407-E458 IonicContact CD2-OE1 3.89Å; H407-E458 IonicContact CD2-OE2 3.27Å; H407-E458 PolarHBondContact CD2-OE2 3.11Å; H407-E458 VanDerWaalsContact CD2-OE2 3.27Å; H407-E458 IonicContact NE2-OE1 3.57Å; H407-E458 IonicContact NE2-OE2 3.55Å; H407-C461 WeakPolarHBondContact NE2-CA 3.16Å; H407-C461 PolarHBondContact NE2-N 3.33Å; H407-C461 VanDerWaalsContact NE2-N 3.16Å
408	K	88	Confident	84.2	Confident	120 Å²	120	66.2 Å²	66.2	52%	0.522	36%	0.359	S	S	.	.	H	α-helix	trans	-58.3	-46.5	175.4	-174.3	175.1	178.6	178.4	0	111.8	H404 P405 V410 W411 D412	H404-K408 PolarHBondContact O-N 3.47Å; H404-K408 VanDerWaalsContact O-N 3.09Å; P405-K408 PolarHBondContact O-N 3.43Å; K408-V410 PolarHBondContact O-N 3.44Å; K408-W411 PolarHBondContact O-N 2.7Å; K408-D412 PolarHBondContact O-N 3.35Å
409	A	91.4	Very high	84.9	Confident	35 Å²	35	65.8 Å²	65.8	29%	0.289	35%	0.353	S	S	.	.	H	α-helix	trans	-59.7	-43.8	178.6	0	0	0	0	0	113	P405 S406 H407 W411 D412 V413 V453	P405-A409 PolarHBondContact O-N 3.49Å; S406-A409 PolarHBondContact O-N 3.08Å; H407-A409 VanDerWaalsContact C-N 3.34Å; H407-A409 PolarHBondContact O-N 2.96Å; A409-W411 VanDerWaalsContact C-N 3.32Å; A409-W411 PolarHBondContact O-N 2.9Å; A409-D412 PolarHBondContact O-N 3.49Å; A409-V413 PolarHBondContact O-N 3.27Å; A409-V413 VanDerWaalsContact O-N 3.14Å; A409-V453 HydrophobicContact CB-CG2 3.94Å
410	V	93	Very high	86.2	Confident	2 Å²	2	58.4 Å²	58.4	1%	0.012	32%	0.321	C	S	.	.	H	α-helix	trans	-60.7	-43.8	176.4	173.3	0	0	0	0	111	S406 H407 K408 V413 L414 L450 V453 A464 R465 A468	S406-V410 WeakPolarHBondContact O-CG2 3.31Å; S406-V410 PolarHBondContact O-N 3.5Å; S406-V410 VanDerWaalsContact O-N 3.16Å; H407-V410 PolarHBondContact O-N 3.23Å; K408-V410 PolarHBondContact O-N 3.44Å; V410-V413 PolarHBondContact O-N 2.97Å; V410-L414 HydrophobicContact CG1-CD1 4.35Å; V410-L414 WeakPolarHBondContact O-CG 3.47Å; V410-L414 PolarHBondContact O-N 3.26Å; V410-L450 HydrophobicContact CG1-CD2 4.44Å; V410-L450 HydrophobicContact CG2-CD2 4.47Å; V410-V453 HydrophobicContact CG2-CG1 4.11Å; V410-V453 HydrophobicContact CG2-CG2 4.43Å; V410-A464 HydrophobicContact CG1-CB 4.15Å; V410-R465 HydrophobicContact CG2-CB 4.12Å; V410-A468 HydrophobicContact CG1-CB 4.07Å
411	W	91.9	Very high	87.8	Confident	54 Å²	54	54 Å²	54	21%	0.205	29%	0.285	C	S	.	.	H	α-helix	trans	-69.9	-32.4	179.6	-80.2	115.7	0	0	0	114	A392 L393 R396 H407 K408 A409 V413 L414 G415	A392-W411 HydrophobicContact CB-CH2 4.23Å; A392-W411 HydrophobicContact CB-CZ3 4.29Å; L393-W411 HydrophobicContact CD2-CE3 3.86Å; L393-W411 HydrophobicContact CD2-CZ3 4.02Å; R396-W411 HydrophobicContact CB-CH2 4.36Å; R396-W411 HydrophobicContact CB-CZ3 4.42Å; R396-W411 VanDerWaalsContact CD-CD2 3.46Å; R396-W411 VanDerWaalsContact NE-CG 3.32Å; H407-W411 PolarHBondContact O-N 3.31Å; H407-W411 VanDerWaalsContact O-N 3.14Å; K408-W411 PolarHBondContact O-N 2.7Å; A409-W411 VanDerWaalsContact C-N 3.32Å; A409-W411 PolarHBondContact O-N 2.9Å; W411-V413 VanDerWaalsContact C-N 3.28Å; W411-L414 HydrophobicContact CD2-CD1 4.17Å; W411-L414 HydrophobicContact CE3-CB 4.36Å; W411-L414 HydrophobicContact CE3-CD1 3.75Å; W411-L414 HydrophobicContact CZ3-CD1 4.19Å; W411-L414 WeakPolarHBondContact O-CB 3.35Å; W411-L414 PolarHBondContact O-N 3.49Å; W411-G415 PolarHBondContact O-N 3.12Å
412	D	92.7	Very high	89.4	Confident	79 Å²	79	49.6 Å²	49.6	42%	0.422	26%	0.257	S	S	.	.	H	α-helix	trans	-63	-40.9	173.8	-65.1	-16.1	0	0	0	109.6	R396 K408 A409 G415 N416	R396-D412 IonicContact NH1-OD1 3.59Å; K408-D412 PolarHBondContact O-N 3.35Å; A409-D412 PolarHBondContact O-N 3.49Å; D412-G415 PolarHBondContact O-N 3.15Å; D412-N416 PolarHBondContact O-N 3.33Å; D412-N416 VanDerWaalsContact O-N 3.11Å
413	V	95.9	Very high	90.9	Very high	9 Å²	9	43.6 Å²	43.6	6%	0.055	23%	0.229	C	C	.	.	H	α-helix	trans	-63.5	-42.1	171.1	177.1	0	0	0	0	112	A409 V410 W411 G415 N416 L417 Q446 A449 L450	A409-V413 PolarHBondContact O-N 3.27Å; A409-V413 VanDerWaalsContact O-N 3.14Å; V410-V413 PolarHBondContact O-N 2.97Å; W411-V413 VanDerWaalsContact C-N 3.28Å; V413-G415 PolarHBondContact O-N 3.22Å; V413-N416 WeakPolarHBondContact O-CB 3.36Å; V413-N416 PolarHBondContact O-N 3.06Å; V413-N416 VanDerWaalsContact O-N 3.16Å; V413-L417 HydrophobicContact CG1-CD1 3.97Å; V413-L417 HydrophobicContact CG1-CG 4.07Å; V413-L417 WeakPolarHBondContact O-CB 3.15Å; V413-L417 WeakPolarHBondContact O-CG 3.49Å; V413-L417 PolarHBondContact O-N 3.17Å; V413-Q446 HydrophobicContact CG1-CB 3.87Å; V413-Q446 HydrophobicContact CG1-CG 4.31Å; V413-A449 HydrophobicContact CG2-CB 4.01Å; V413-L450 HydrophobicContact CB-CD2 4Å; V413-L450 HydrophobicContact CB-CG 4.28Å; V413-L450 HydrophobicContact CG1-CD1 3.94Å; V413-L450 HydrophobicContact CG1-CD2 3.94Å; V413-L450 HydrophobicContact CG1-CG 3.77Å; V413-L450 HydrophobicContact CG2-CD2 4.19Å; V413-L450 HydrophobicContact CG2-CG 4.32Å
414	L	95.2	Very high	92.2	Very high	24 Å²	24	39.5 Å²	39.5	13%	0.126	21%	0.21	C	C	.	.	H	α-helix	trans	-60.5	-34.4	175.7	-72.6	174.6	0	0	0	112.4	L389 L393 V410 W411 L417 S418 A468 L471	L389-L414 HydrophobicContact CD1-CB 4.13Å; L389-L414 HydrophobicContact CD1-CD2 4.03Å; L393-L414 HydrophobicContact CD2-CB 4.42Å; V410-L414 HydrophobicContact CG1-CD1 4.35Å; V410-L414 WeakPolarHBondContact O-CG 3.47Å; V410-L414 PolarHBondContact O-N 3.26Å; W411-L414 HydrophobicContact CD2-CD1 4.17Å; W411-L414 HydrophobicContact CE3-CB 4.36Å; W411-L414 HydrophobicContact CE3-CD1 3.75Å; W411-L414 HydrophobicContact CZ3-CD1 4.19Å; W411-L414 WeakPolarHBondContact O-CB 3.35Å; W411-L414 PolarHBondContact O-N 3.49Å; L414-L417 HydrophobicContact CD2-CD1 4.4Å; L414-S418 WeakPolarHBondContact O-CB 3.41Å; L414-S418 PolarHBondContact O-N 2.92Å; L414-A468 HydrophobicContact CD2-CB 3.8Å; L414-A468 HydrophobicContact CG-CB 4.27Å; L414-L471 HydrophobicContact CD2-CD2 3.72Å
415	G	94.8	Very high	92.9	Very high	20 Å²	20	36.1 Å²	36.1	21%	0.206	19%	0.194	C	C	.	.	H	α-helix	trans	-60.7	-52.3	170.9	0	0	0	0	0	111.8	W411 D412 V413 L417 S418 E419	W411-G415 PolarHBondContact O-N 3.12Å; D412-G415 PolarHBondContact O-N 3.15Å; V413-G415 PolarHBondContact O-N 3.22Å; G415-L417 VanDerWaalsContact C-N 3.34Å; G415-L417 PolarHBondContact O-N 3.3Å; G415-S418 VanDerWaalsContact O-CB 3.32Å; G415-S418 WeakPolarHBondContact O-CB 3.48Å; G415-S418 PolarHBondContact O-N 2.94Å; G415-S418 VanDerWaalsContact O-N 3.11Å; G415-E419 PolarHBondContact O-N 2.8Å
416	N	96.5	Very high	93.3	Very high	67 Å²	67	35.5 Å²	35.5	36%	0.358	19%	0.192	S	C	.	.	H	α-helix	trans	-59.4	-44	176.9	-61.1	-22.1	0	0	0	111.8	D412 V413 S418 E419 I420 Q446	D412-N416 PolarHBondContact O-N 3.33Å; D412-N416 VanDerWaalsContact O-N 3.11Å; V413-N416 WeakPolarHBondContact O-CB 3.36Å; V413-N416 PolarHBondContact O-N 3.06Å; V413-N416 VanDerWaalsContact O-N 3.16Å; N416-S418 VanDerWaalsContact C-N 3.26Å; N416-S418 PolarHBondContact O-N 3.24Å; N416-E419 PolarHBondContact O-N 3.38Å; N416-I420 WeakPolarHBondContact O-CD1 3.39Å; N416-I420 VanDerWaalsContact O-CG1 3.25Å; N416-I420 WeakPolarHBondContact O-CG1 3.26Å; N416-I420 PolarHBondContact O-N 2.91Å; N416-Q446 HydrophobicContact CB-CG 4.34Å; N416-Q446 VanDerWaalsContact CB-OE1 3.28Å; N416-Q446 PolarHBondContact ND2-OE1 3.08Å
417	L	97	Very high	93.6	Very high	0 Å²	0	35.5 Å²	35.5	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-61.3	-35	177.2	-72.3	175.6	0	0	0	111.9	V413 L414 G415 Q421 L443 Q446 L471 A472 I475	V413-L417 HydrophobicContact CG1-CD1 3.97Å; V413-L417 HydrophobicContact CG1-CG 4.07Å; V413-L417 WeakPolarHBondContact O-CB 3.15Å; V413-L417 WeakPolarHBondContact O-CG 3.49Å; V413-L417 PolarHBondContact O-N 3.17Å; L414-L417 HydrophobicContact CD2-CD1 4.4Å; G415-L417 VanDerWaalsContact C-N 3.34Å; G415-L417 PolarHBondContact O-N 3.3Å; L417-Q421 WeakPolarHBondContact O-CB 3.48Å; L417-Q421 PolarHBondContact O-N 3.37Å; L417-L443 HydrophobicContact CD2-CD2 3.83Å; L417-Q446 HydrophobicContact CD2-CB 3.81Å; L417-Q446 HydrophobicContact CD2-CG 3.82Å; L417-Q446 HydrophobicContact CG-CB 4.34Å; L417-Q446 HydrophobicContact CG-CG 4.27Å; L417-L471 HydrophobicContact CB-CD2 4.44Å; L417-L471 HydrophobicContact CD1-CD2 4.12Å; L417-L471 HydrophobicContact CD1-CG 4.42Å; L417-A472 HydrophobicContact CD1-CB 4.03Å; L417-A472 HydrophobicContact CD2-CB 3.8Å; L417-I475 HydrophobicContact CB-CD1 4.21Å; L417-I475 HydrophobicContact CD2-CD1 4.22Å
418	S	95.1	Very high	93.6	Very high	1 Å²	1	41.8 Å²	41.8	1%	0.007	23%	0.226	C	C	.	.	H	α-helix	trans	-66.2	-38.2	175.8	-173.4	0	0	0	0	112.9	Y386 K390 L414 G415 N416 G422	Y386-S418 WeakPolarHBondContact CE2-O 3.46Å; K390-S418 VanDerWaalsContact CD-OG 3.25Å; K390-S418 WeakPolarHBondContact CD-OG 3.31Å; K390-S418 WeakPolarHBondContact CE-OG 3.36Å; K390-S418 PolarHBondContact NZ-OG 3.42Å; L414-S418 WeakPolarHBondContact O-CB 3.41Å; L414-S418 PolarHBondContact O-N 2.92Å; G415-S418 VanDerWaalsContact O-CB 3.32Å; G415-S418 WeakPolarHBondContact O-CB 3.48Å; G415-S418 PolarHBondContact O-N 2.94Å; G415-S418 VanDerWaalsContact O-N 3.11Å; N416-S418 VanDerWaalsContact C-N 3.26Å; N416-S418 PolarHBondContact O-N 3.24Å; S418-G422 PolarHBondContact O-N 2.94Å
419	E	95.3	Very high	93.5	Very high	125 Å²	125	37.4 Å²	37.4	58%	0.584	21%	0.214	S	C	*	.	H	α-helix	trans	-68.5	-49.8	175.2	-66.2	178.1	178.6	0	0	110.6	G415 N416 Q421 G422 E423	G415-E419 PolarHBondContact O-N 2.8Å; N416-E419 PolarHBondContact O-N 3.38Å; E419-Q421 VanDerWaalsContact C-N 3.32Å; E419-Q421 PolarHBondContact O-N 2.85Å; E419-G422 WeakPolarHBondContact O-CA 3.39Å; E419-G422 PolarHBondContact O-N 3.01Å; E419-E423 PolarHBondContact O-N 3.43Å; E419-E423 VanDerWaalsContact O-N 3.15Å
420	I	96.4	Very high	93.2	Very high	10 Å²	10	38.2 Å²	38.2	5%	0.051	21%	0.214	C	C	.	.	H	α-helix	trans	-59.3	-43.6	177.7	-61.9	161.5	0	0	0	110.7	N416 G422 E423 V424 L439 L442 L443 Q446	N416-I420 WeakPolarHBondContact O-CD1 3.39Å; N416-I420 VanDerWaalsContact O-CG1 3.25Å; N416-I420 WeakPolarHBondContact O-CG1 3.26Å; N416-I420 PolarHBondContact O-N 2.91Å; I420-G422 VanDerWaalsContact C-N 3.26Å; I420-G422 PolarHBondContact O-N 3.1Å; I420-E423 PolarHBondContact O-N 3.35Å; I420-E423 VanDerWaalsContact O-N 3.12Å; I420-V424 HydrophobicContact CG2-CG2 4.13Å; I420-V424 VanDerWaalsContact O-CG2 3.31Å; I420-V424 WeakPolarHBondContact O-CG2 3.42Å; I420-V424 PolarHBondContact O-N 3.38Å; I420-L439 HydrophobicContact CG2-CD2 4.21Å; I420-L442 HydrophobicContact CD1-CB 3.93Å; I420-L442 HydrophobicContact CG1-CB 4.27Å; I420-L443 HydrophobicContact CB-CD2 4.44Å; I420-L443 HydrophobicContact CG2-CD1 4.27Å; I420-L443 HydrophobicContact CG2-CD2 3.67Å; I420-L443 HydrophobicContact CG2-CG 3.76Å; I420-Q446 HydrophobicContact CD1-CG 3.72Å
421	Q	95.7	Very high	92.8	Very high	2 Å²	2	44.6 Å²	44.6	1%	0.009	24%	0.238	C	C	.	.	H	α-helix	trans	-61.9	-34.6	177.8	-171.2	173.6	13.2	0	0	112	T382 T385 Y386 L417 E419 V424 L425 I475	T382-Q421 PolarHBondContact O-NE2 3.38Å; T385-Q421 PolarHBondContact OG1-NE2 2.65Å; Y386-Q421 HydrophobicContact CD2-CB 4.12Å; Y386-Q421 HydrophobicContact CD2-CG 3.9Å; L417-Q421 WeakPolarHBondContact O-CB 3.48Å; L417-Q421 PolarHBondContact O-N 3.37Å; E419-Q421 VanDerWaalsContact C-N 3.32Å; E419-Q421 PolarHBondContact O-N 2.85Å; Q421-V424 PolarHBondContact O-N 3.06Å; Q421-L425 HydrophobicContact CG-CD1 4.49Å; Q421-L425 WeakPolarHBondContact O-CB 3.35Å; Q421-L425 VanDerWaalsContact O-CG 3.26Å; Q421-L425 WeakPolarHBondContact O-CG 3.33Å; Q421-L425 PolarHBondContact O-N 2.93Å; Q421-I475 HydrophobicContact CB-CD1 3.9Å; Q421-I475 HydrophobicContact CB-CG1 4.23Å; Q421-I475 HydrophobicContact CB-CG2 4.49Å; Q421-I475 HydrophobicContact CG-CD1 4.22Å; Q421-I475 HydrophobicContact CG-CG1 4.06Å
422	G	93.4	Very high	92.4	Very high	12 Å²	12	47.6 Å²	47.6	12%	0.124	26%	0.262	C	S	.	.	H	α-helix	trans	-62.1	-44	172.6	0	0	0	0	0	112.5	S418 E419 I420 L425 S426	S418-G422 PolarHBondContact O-N 2.94Å; E419-G422 WeakPolarHBondContact O-CA 3.39Å; E419-G422 PolarHBondContact O-N 3.01Å; I420-G422 VanDerWaalsContact C-N 3.26Å; I420-G422 PolarHBondContact O-N 3.1Å; G422-L425 PolarHBondContact O-N 3.36Å; G422-S426 PolarHBondContact O-N 3.07Å; G422-S426 PolarHBondContact O-OG 2.89Å
423	E	94.9	Very high	92.3	Very high	74 Å²	74	46.7 Å²	46.7	35%	0.346	26%	0.258	S	S	.	.	H	α-helix	trans	-67.3	-38.8	174.5	-63.9	-179	-158.8	0	0	112.2	E419 I420 L425 S426 F427 R438 L439	E419-E423 PolarHBondContact O-N 3.43Å; E419-E423 VanDerWaalsContact O-N 3.15Å; I420-E423 PolarHBondContact O-N 3.35Å; I420-E423 VanDerWaalsContact O-N 3.12Å; E423-L425 VanDerWaalsContact C-N 3.31Å; E423-L425 PolarHBondContact O-N 3.35Å; E423-S426 CarbonylContact O-C 3.59Å; E423-S426 PolarHBondContact O-N 3.26Å; E423-S426 PolarHBondContact O-OG 3.46Å; E423-F427 PolarHBondContact O-N 3.03Å; E423-R438 IonicContact OE2-CZ 3.5Å; E423-R438 IonicContact OE2-NH1 3.97Å; E423-R438 PolarHBondContact OE2-NH1 3.44Å; E423-R438 IonicContact OE2-NH2 2.71Å; E423-R438 PolarHBondContact OE2-NH2 3.1Å; E423-L439 HydrophobicContact CB-CD2 3.75Å; E423-L439 WeakPolarHBondContact OE2-CD2 3.43Å
424	V	95.4	Very high	92.2	Very high	0 Å²	0	54.9 Å²	54.9	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-64.7	-36.4	174.6	172.2	0	0	0	0	110.6	I420 Q421 S426 F427 L439 L443 I475 Y478 L479 K482	I420-V424 HydrophobicContact CG2-CG2 4.13Å; I420-V424 VanDerWaalsContact O-CG2 3.31Å; I420-V424 WeakPolarHBondContact O-CG2 3.42Å; I420-V424 PolarHBondContact O-N 3.38Å; Q421-V424 PolarHBondContact O-N 3.06Å; V424-S426 VanDerWaalsContact C-N 3.3Å; V424-S426 PolarHBondContact O-N 3.23Å; V424-F427 WeakPolarHBondContact O-CB 3.49Å; V424-F427 PolarHBondContact O-N 3.42Å; V424-L439 HydrophobicContact CG2-CB 4.48Å; V424-L439 HydrophobicContact CG2-CD1 4.17Å; V424-L439 HydrophobicContact CG2-CD2 4.24Å; V424-L443 HydrophobicContact CG2-CD1 4.48Å; V424-I475 HydrophobicContact CB-CG2 4.27Å; V424-I475 HydrophobicContact CG1-CG2 4.29Å; V424-I475 HydrophobicContact CG2-CG2 3.91Å; V424-Y478 HydrophobicContact CG1-CD1 3.66Å; V424-Y478 HydrophobicContact CG1-CE1 4.09Å; V424-L479 HydrophobicContact CG1-CB 3.96Å; V424-L479 HydrophobicContact CG1-CD1 4.14Å; V424-L479 HydrophobicContact CG2-CB 4.49Å; V424-L479 HydrophobicContact CG2-CD1 4.3Å; V424-L479 HydrophobicContact CG2-CD2 4.48Å; V424-K482 PolarHBondContact O-NZ 3.23Å
425	L	93.7	Very high	92.1	Very high	1 Å²	1	56.4 Å²	56.4	1%	0.005	30%	0.301	C	S	.	.	H	α-helix	trans	-65.4	-31.5	176.8	-80.2	169.5	0	0	0	113.1	K331 T382 L383 Y386 Q421 G422 E423 Y478 K482	K331-L425 HydrophobicContact CD-CB 4.4Å; K331-L425 HydrophobicContact CD-CD2 4.42Å; K331-L425 PolarHBondContact NZ-O 2.99Å; T382-L425 HydrophobicContact CG2-CD2 4.23Å; L383-L425 HydrophobicContact CD1-CD1 3.97Å; L383-L425 HydrophobicContact CD1-CD2 4.37Å; Y386-L425 HydrophobicContact CD1-CD1 3.89Å; Y386-L425 HydrophobicContact CD2-CD1 3.83Å; Y386-L425 HydrophobicContact CE1-CD1 4.38Å; Y386-L425 HydrophobicContact CE2-CD1 4.29Å; Y386-L425 HydrophobicContact CG-CD1 3.59Å; Q421-L425 HydrophobicContact CG-CD1 4.49Å; Q421-L425 WeakPolarHBondContact O-CB 3.35Å; Q421-L425 VanDerWaalsContact O-CG 3.26Å; Q421-L425 WeakPolarHBondContact O-CG 3.33Å; Q421-L425 PolarHBondContact O-N 2.93Å; G422-L425 PolarHBondContact O-N 3.36Å; E423-L425 VanDerWaalsContact C-N 3.31Å; E423-L425 PolarHBondContact O-N 3.35Å; L425-Y478 HydrophobicContact CD2-CE1 4.1Å; L425-K482 PolarHBondContact O-NZ 3.5Å
426	S	91.9	Very high	92.1	Very high	78 Å²	78	55.9 Å²	55.9	55%	0.545	29%	0.293	S	S	.	.	H	α-helix	trans	-93.4	-9.5	176.4	61.1	0	0	0	0	114.4	G422 E423 V424 D428	G422-S426 PolarHBondContact O-N 3.07Å; G422-S426 PolarHBondContact O-OG 2.89Å; E423-S426 CarbonylContact O-C 3.59Å; E423-S426 PolarHBondContact O-N 3.26Å; E423-S426 PolarHBondContact O-OG 3.46Å; V424-S426 VanDerWaalsContact C-N 3.3Å; V424-S426 PolarHBondContact O-N 3.23Å; S426-D428 PolarHBondContact O-N 2.88Å
427	F	92.6	Very high	91.9	Very high	8 Å²	8	56.8 Å²	56.8	4%	0.035	30%	0.297	C	S	.	.			trans	-57.1	133.3	174	179.2	-104	0	0	0	111	E423 V424 G429 N435 Y436 L439 L479 K482	E423-F427 PolarHBondContact O-N 3.03Å; V424-F427 WeakPolarHBondContact O-CB 3.49Å; V424-F427 PolarHBondContact O-N 3.42Å; F427-G429 WeakPolarHBondContact CE1-O 3.44Å; F427-G429 WeakPolarHBondContact CZ-O 3.43Å; F427-N435 HydrophobicContact CD2-CB 4.44Å; F427-N435 HydrophobicContact CE2-CB 4.2Å; F427-Y436 HydrophobicContact CE1-CD2 4.29Å; F427-Y436 HydrophobicContact CZ-CD2 4.17Å; F427-Y436 HydrophobicContact CZ-CG 4.48Å; F427-L439 HydrophobicContact CB-CD1 4.22Å; F427-L439 HydrophobicContact CD2-CD1 3.99Å; F427-L439 HydrophobicContact CG-CD1 4.26Å; F427-L479 HydrophobicContact CB-CD1 4.46Å; F427-L479 HydrophobicContact CD1-CD1 3.68Å; F427-L479 HydrophobicContact CE1-CD1 4.04Å; F427-L479 HydrophobicContact CG-CD1 3.99Å; F427-K482 HydrophobicContact CD1-CD 4.21Å; F427-K482 HydrophobicContact CD1-CG 4.49Å; F427-K482 WeakPolarHBondContact O-CD 3.45Å
428	D	85.9	Confident	91.9	Very high	156 Å²	156	61.2 Å²	61.2	83%	0.834	31%	0.313	S	S	*	.			trans	-144.6	95.8	175.4	-174	26.3	0	0	0	107.2	S426	S426-D428 PolarHBondContact O-N 2.88Å
429	G	85.1	Confident	92	Very high	28 Å²	28	61.2 Å²	61.2	29%	0.289	31%	0.313	S	S	.	.			trans	177.7	-178.2	-170.1	0	0	0	0	0	111.9	F427 S483	F427-G429 WeakPolarHBondContact CE1-O 3.44Å; F427-G429 WeakPolarHBondContact CZ-O 3.43Å; G429-S483 WeakPolarHBondContact O-CA 3.42Å
430	N	84.5	Confident	92	Very high	52 Å²	52	58.8 Å²	58.8	28%	0.278	30%	0.302	S	S	.	.			trans	-115.4	175.5	-179.3	67.8	33.5	0	0	0	111.9	T432 D433 Y436	N430-T432 PolarHBondContact O-N 2.97Å; N430-T432 VanDerWaalsContact O-N 3.07Å; N430-T432 WeakPolarHBondContact OD1-CB 3.29Å; N430-T432 PolarHBondContact OD1-N 3.3Å; N430-T432 PolarHBondContact OD1-OG1 3.05Å; N430-D433 WeakPolarHBondContact O-CB 3.16Å; N430-D433 PolarHBondContact O-N 3.3Å; N430-D433 PolarHBondContact OD1-N 2.94Å; N430-Y436 WeakPolarHBondContact O-CB 3.42Å
431	R	84.1	Confident	92.1	Very high	136 Å²	136	63 Å²	63	51%	0.513	32%	0.321	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61	-16.9	-178.6	-67.5	-171.6	166.1	154.8	-4.5	115.2	Y436 D480 S483	R431-Y436 HydrophobicContact CB-CD1 4.32Å; R431-Y436 HydrophobicContact CB-CE1 4.24Å; R431-Y436 HydrophobicContact CG-CD2 4.38Å; R431-Y436 HydrophobicContact CG-CE1 4.13Å; R431-Y436 HydrophobicContact CG-CE2 3.89Å; R431-D480 IonicContact CZ-OD1 3.44Å; R431-D480 IonicContact NE-OD1 2.73Å; R431-D480 PolarHBondContact NE-OD1 3.47Å; R431-D480 IonicContact NH2-OD1 2.56Å; R431-D480 PolarHBondContact NH2-OD1 3.33Å; R431-S483 VanDerWaalsContact CG-OG 3.22Å; R431-S483 WeakPolarHBondContact CG-OG 3.37Å
432	T	84.3	Confident	92.2	Very high	117 Å²	117	65.2 Å²	65.2	72%	0.718	33%	0.333	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.2	-10	178.2	68.8	0	0	0	0	113	N430	N430-T432 PolarHBondContact O-N 2.97Å; N430-T432 VanDerWaalsContact O-N 3.07Å; N430-T432 WeakPolarHBondContact OD1-CB 3.29Å; N430-T432 PolarHBondContact OD1-N 3.3Å; N430-T432 PolarHBondContact OD1-OG1 3.05Å
433	D	90	Very high	92.3	Very high	61 Å²	61	64.6 Å²	64.6	33%	0.326	33%	0.327	S	S	.	.	S	Bend	trans	-69.5	137.9	177.9	-169.5	-6	0	0	0	110.9	N430 N435 Y436 I437	N430-D433 WeakPolarHBondContact O-CB 3.16Å; N430-D433 PolarHBondContact O-N 3.3Å; N430-D433 PolarHBondContact OD1-N 2.94Å; D433-N435 PolarHBondContact O-N 3.32Å; D433-N435 PolarHBondContact OD1-N 3.11Å; D433-Y436 WeakPolarHBondContact O-CB 3.09Å; D433-Y436 PolarHBondContact O-N 3Å; D433-Y436 VanDerWaalsContact O-N 3.13Å; D433-I437 PolarHBondContact O-N 3.38Å
434	K	93.9	Very high	92.4	Very high	180 Å²	180	64 Å²	64	78%	0.783	33%	0.328	S	S	*	.	H	α-helix	trans	-56.5	-33.3	171.8	-65.7	-178.4	-179.8	178.6	0	111.5	R438	K434-R438 WeakPolarHBondContact O-CB 3.5Å; K434-R438 PolarHBondContact O-N 3.15Å
435	N	93.8	Very high	92.5	Very high	56 Å²	56	68.9 Å²	68.9	30%	0.299	35%	0.349	S	S	.	.	H	α-helix	trans	-68.2	-38.7	179.2	-163.7	28.3	0	0	0	112	F427 D433 R438 L439	F427-N435 HydrophobicContact CD2-CB 4.44Å; F427-N435 HydrophobicContact CE2-CB 4.2Å; D433-N435 PolarHBondContact O-N 3.32Å; D433-N435 PolarHBondContact OD1-N 3.11Å; N435-R438 PolarHBondContact O-N 3.27Å; N435-R438 PolarHBondContact OD1-NE 2.99Å; N435-R438 PolarHBondContact OD1-NH2 3.41Å; N435-L439 VanDerWaalsContact O-CG 3.28Å; N435-L439 WeakPolarHBondContact O-CG 3.43Å; N435-L439 PolarHBondContact O-N 3.11Å
436	Y	93.6	Very high	92.7	Very high	10 Å²	10	69.8 Å²	69.8	4%	0.039	35%	0.354	C	S	.	.	H	α-helix	trans	-58.6	-54	172.8	175.3	-86	0	0	0	110.9	F427 N430 R431 D433 R438 L439 E440 L479 D480 S483	F427-Y436 HydrophobicContact CE1-CD2 4.29Å; F427-Y436 HydrophobicContact CZ-CD2 4.17Å; F427-Y436 HydrophobicContact CZ-CG 4.48Å; N430-Y436 WeakPolarHBondContact O-CB 3.42Å; R431-Y436 HydrophobicContact CB-CD1 4.32Å; R431-Y436 HydrophobicContact CB-CE1 4.24Å; R431-Y436 HydrophobicContact CG-CD2 4.38Å; R431-Y436 HydrophobicContact CG-CE1 4.13Å; R431-Y436 HydrophobicContact CG-CE2 3.89Å; D433-Y436 WeakPolarHBondContact O-CB 3.09Å; D433-Y436 PolarHBondContact O-N 3Å; D433-Y436 VanDerWaalsContact O-N 3.13Å; Y436-R438 VanDerWaalsContact C-N 3.27Å; Y436-R438 PolarHBondContact O-N 2.89Å; Y436-L439 PolarHBondContact O-N 2.91Å; Y436-E440 HydrophobicContact CE1-CB 4.38Å; Y436-E440 PolarHBondContact O-N 3.29Å; Y436-L479 HydrophobicContact CD2-CD1 4.01Å; Y436-L479 HydrophobicContact CD2-CD2 4.22Å; Y436-L479 HydrophobicContact CD2-CG 3.85Å; Y436-L479 HydrophobicContact CE2-CD1 4.35Å; Y436-L479 HydrophobicContact CE2-CD2 4.17Å; Y436-L479 HydrophobicContact CE2-CG 3.73Å; Y436-D480 PolarHBondContact OH-OD1 3.26Å; Y436-S483 WeakPolarHBondContact CE2-OG 3.47Å
437	I	93.9	Very high	92.9	Very high	86 Å²	86	67.6 Å²	67.6	44%	0.441	34%	0.336	S	S	.	.	H	α-helix	trans	-58.9	-41.4	-177.3	-60.5	167.2	0	0	0	110.6	D433 E441	D433-I437 PolarHBondContact O-N 3.38Å; I437-E441 WeakPolarHBondContact O-CB 3.37Å; I437-E441 PolarHBondContact O-N 3.19Å
438	R	96.8	Very high	93.1	Very high	93 Å²	93	72.5 Å²	72.5	35%	0.351	36%	0.362	S	S	.	.	H	α-helix	trans	-62.3	-46.3	176.1	-176.2	-168.9	64.1	90.7	3.8	111.9	E423 K434 N435 Y436 E441 L442	E423-R438 IonicContact OE2-CZ 3.5Å; E423-R438 IonicContact OE2-NH1 3.97Å; E423-R438 PolarHBondContact OE2-NH1 3.44Å; E423-R438 IonicContact OE2-NH2 2.71Å; E423-R438 PolarHBondContact OE2-NH2 3.1Å; K434-R438 WeakPolarHBondContact O-CB 3.5Å; K434-R438 PolarHBondContact O-N 3.15Å; N435-R438 PolarHBondContact O-N 3.27Å; N435-R438 PolarHBondContact OD1-NE 2.99Å; N435-R438 PolarHBondContact OD1-NH2 3.41Å; Y436-R438 VanDerWaalsContact C-N 3.27Å; Y436-R438 PolarHBondContact O-N 2.89Å; R438-E441 PolarHBondContact O-N 3.07Å; R438-L442 HydrophobicContact CG-CD1 4.35Å; R438-L442 WeakPolarHBondContact O-CG 3.39Å; R438-L442 PolarHBondContact O-N 3.35Å
439	L	96.9	Very high	93.5	Very high	0 Å²	0	67 Å²	67	0%	0	34%	0.338	C	S	.	.	H	α-helix	trans	-64.9	-42.6	-179.7	-71.9	170	0	0	0	111.4	I420 E423 V424 F427 N435 Y436 L442 L443 L479	I420-L439 HydrophobicContact CG2-CD2 4.21Å; E423-L439 HydrophobicContact CB-CD2 3.75Å; E423-L439 WeakPolarHBondContact OE2-CD2 3.43Å; V424-L439 HydrophobicContact CG2-CB 4.48Å; V424-L439 HydrophobicContact CG2-CD1 4.17Å; V424-L439 HydrophobicContact CG2-CD2 4.24Å; F427-L439 HydrophobicContact CB-CD1 4.22Å; F427-L439 HydrophobicContact CD2-CD1 3.99Å; F427-L439 HydrophobicContact CG-CD1 4.26Å; N435-L439 VanDerWaalsContact O-CG 3.28Å; N435-L439 WeakPolarHBondContact O-CG 3.43Å; N435-L439 PolarHBondContact O-N 3.11Å; Y436-L439 PolarHBondContact O-N 2.91Å; L439-L442 PolarHBondContact O-N 3.03Å; L439-L443 VanDerWaalsContact O-CG 3.32Å; L439-L443 WeakPolarHBondContact O-CG 3.33Å; L439-L443 PolarHBondContact O-N 3.41Å; L439-L479 HydrophobicContact CB-CD2 3.69Å; L439-L479 HydrophobicContact CD1-CD1 4.14Å
440	E	96.1	Very high	94	Very high	74 Å²	74	65.6 Å²	65.6	35%	0.346	32%	0.324	S	S	.	.	H	α-helix	trans	-59.3	-45.2	173.6	-177.5	-177.6	-144.1	0	0	111.6	Y436 L442 L443 T444 L476	Y436-E440 HydrophobicContact CE1-CB 4.38Å; Y436-E440 PolarHBondContact O-N 3.29Å; E440-L442 PolarHBondContact O-N 2.82Å; E440-L443 PolarHBondContact O-N 2.98Å; E440-T444 WeakPolarHBondContact O-CB 3.17Å; E440-T444 PolarHBondContact O-N 2.94Å; E440-T444 PolarHBondContact O-OG1 2.77Å; E440-L476 HydrophobicContact CG-CD2 4.17Å
441	E	96.9	Very high	94.4	Very high	99 Å²	99	68.3 Å²	68.3	46%	0.463	34%	0.338	S	S	.	.	H	α-helix	trans	-63.3	-42	177	-168.2	-169.8	161.2	0	0	111.8	I437 R438 T444 K445	I437-E441 WeakPolarHBondContact O-CB 3.37Å; I437-E441 PolarHBondContact O-N 3.19Å; R438-E441 PolarHBondContact O-N 3.07Å; E441-T444 PolarHBondContact O-N 3.33Å; E441-K445 WeakPolarHBondContact O-CG 3.49Å; E441-K445 PolarHBondContact O-N 3.46Å; E441-K445 WeakPolarHBondContact OE1-CE 3.25Å; E441-K445 IonicContact OE1-NZ 2.85Å; E441-K445 PolarHBondContact OE1-NZ 3.21Å
442	L	97.4	Very high	94.8	Very high	48 Å²	48	65.8 Å²	65.8	25%	0.251	35%	0.347	S	S	.	.	H	α-helix	trans	-62.6	-42.5	176.8	-74.3	174.7	0	0	0	112	I420 R438 L439 E440 K445 Q446	I420-L442 HydrophobicContact CD1-CB 3.93Å; I420-L442 HydrophobicContact CG1-CB 4.27Å; R438-L442 HydrophobicContact CG-CD1 4.35Å; R438-L442 WeakPolarHBondContact O-CG 3.39Å; R438-L442 PolarHBondContact O-N 3.35Å; L439-L442 PolarHBondContact O-N 3.03Å; E440-L442 PolarHBondContact O-N 2.82Å; L442-K445 PolarHBondContact O-N 2.92Å; L442-Q446 WeakPolarHBondContact O-CG 3.06Å; L442-Q446 PolarHBondContact O-N 2.92Å; L442-Q446 VanDerWaalsContact O-N 3.1Å; L442-Q446 PolarHBondContact O-NE2 3.38Å
443	L	97.3	Very high	95.2	Very high	0 Å²	0	60.8 Å²	60.8	0%	0	32%	0.316	C	S	.	.	H	α-helix	trans	-65.7	-42.1	176.2	-71.6	163.5	0	0	0	111.5	L417 I420 V424 L439 E440 K445 Q446 L447 I475 L476 L479	L417-L443 HydrophobicContact CD2-CD2 3.83Å; I420-L443 HydrophobicContact CB-CD2 4.44Å; I420-L443 HydrophobicContact CG2-CD1 4.27Å; I420-L443 HydrophobicContact CG2-CD2 3.67Å; I420-L443 HydrophobicContact CG2-CG 3.76Å; V424-L443 HydrophobicContact CG2-CD1 4.48Å; L439-L443 VanDerWaalsContact O-CG 3.32Å; L439-L443 WeakPolarHBondContact O-CG 3.33Å; L439-L443 PolarHBondContact O-N 3.41Å; E440-L443 PolarHBondContact O-N 2.98Å; L443-K445 VanDerWaalsContact C-N 3.31Å; L443-K445 PolarHBondContact O-N 3.15Å; L443-Q446 WeakPolarHBondContact O-CB 3.32Å; L443-Q446 PolarHBondContact O-N 2.98Å; L443-Q446 VanDerWaalsContact O-N 3.1Å; L443-L447 PolarHBondContact O-N 3.38Å; L443-I475 HydrophobicContact CD1-CG2 3.87Å; L443-I475 HydrophobicContact CD2-CB 4Å; L443-I475 HydrophobicContact CD2-CG2 3.69Å; L443-I475 HydrophobicContact CG-CG2 4.43Å; L443-L476 HydrophobicContact CB-CD1 4.17Å; L443-L476 HydrophobicContact CB-CD2 3.61Å; L443-L476 HydrophobicContact CB-CG 3.7Å; L443-L476 HydrophobicContact CD1-CD2 3.53Å; L443-L476 HydrophobicContact CD1-CG 3.74Å; L443-L476 HydrophobicContact CG-CD2 4.18Å; L443-L476 HydrophobicContact CG-CG 4.23Å; L443-L479 HydrophobicContact CD1-CD2 4.18Å
444	T	96.2	Very high	95.1	Very high	62 Å²	62	62.8 Å²	62.8	38%	0.38	33%	0.326	S	S	.	.	H	α-helix	trans	-61	-41.6	175.6	-56.9	0	0	0	0	111.2	E440 E441 Q446 L447 L448	E440-T444 WeakPolarHBondContact O-CB 3.17Å; E440-T444 PolarHBondContact O-N 2.94Å; E440-T444 PolarHBondContact O-OG1 2.77Å; E441-T444 PolarHBondContact O-N 3.33Å; T444-Q446 VanDerWaalsContact C-N 3.32Å; T444-Q446 PolarHBondContact O-N 2.97Å; T444-L447 WeakPolarHBondContact O-CB 3.49Å; T444-L447 PolarHBondContact O-N 3.47Å; T444-L448 WeakPolarHBondContact O-CG 3.5Å; T444-L448 PolarHBondContact O-N 3.15Å
445	K	97.5	Very high	94.5	Very high	101 Å²	101	54.8 Å²	54.8	44%	0.439	29%	0.293	S	S	.	.	H	α-helix	trans	-61	-38.4	173.4	-74.9	171.4	-176.3	164.4	0	112.5	E441 L442 L443 L448 A449	E441-K445 WeakPolarHBondContact O-CG 3.49Å; E441-K445 PolarHBondContact O-N 3.46Å; E441-K445 WeakPolarHBondContact OE1-CE 3.25Å; E441-K445 IonicContact OE1-NZ 2.85Å; E441-K445 PolarHBondContact OE1-NZ 3.21Å; L442-K445 PolarHBondContact O-N 2.92Å; L443-K445 VanDerWaalsContact C-N 3.31Å; L443-K445 PolarHBondContact O-N 3.15Å; K445-L448 PolarHBondContact O-N 2.6Å; K445-A449 WeakPolarHBondContact O-CB 3.35Å; K445-A449 PolarHBondContact O-N 3.19Å
446	Q	97.6	Very high	93.9	Very high	21 Å²	21	58.3 Å²	58.3	10%	0.098	31%	0.308	C	S	.	.	H	α-helix	trans	-66.8	-38.1	175.8	-62.4	-35.6	-70	0	0	112.3	V413 N416 L417 I420 L442 L443 T444 A449 L450	V413-Q446 HydrophobicContact CG1-CB 3.87Å; V413-Q446 HydrophobicContact CG1-CG 4.31Å; N416-Q446 HydrophobicContact CB-CG 4.34Å; N416-Q446 VanDerWaalsContact CB-OE1 3.28Å; N416-Q446 PolarHBondContact ND2-OE1 3.08Å; L417-Q446 HydrophobicContact CD2-CB 3.81Å; L417-Q446 HydrophobicContact CD2-CG 3.82Å; L417-Q446 HydrophobicContact CG-CB 4.34Å; L417-Q446 HydrophobicContact CG-CG 4.27Å; I420-Q446 HydrophobicContact CD1-CG 3.72Å; L442-Q446 WeakPolarHBondContact O-CG 3.06Å; L442-Q446 PolarHBondContact O-N 2.92Å; L442-Q446 VanDerWaalsContact O-N 3.1Å; L442-Q446 PolarHBondContact O-NE2 3.38Å; L443-Q446 WeakPolarHBondContact O-CB 3.32Å; L443-Q446 PolarHBondContact O-N 2.98Å; L443-Q446 VanDerWaalsContact O-N 3.1Å; T444-Q446 VanDerWaalsContact C-N 3.32Å; T444-Q446 PolarHBondContact O-N 2.97Å; Q446-A449 PolarHBondContact O-N 3.5Å; Q446-L450 WeakPolarHBondContact O-CG 3.48Å; Q446-L450 PolarHBondContact O-N 2.96Å
447	L	96.6	Very high	93.1	Very high	32 Å²	32	60.2 Å²	60.2	17%	0.168	33%	0.33	C	S	.	.	H	α-helix	trans	-61.1	-47.9	174.3	-73.2	171.3	0	0	0	111.5	L443 T444 A449 L450 D451 V469 A472 Q473 L476	L443-L447 PolarHBondContact O-N 3.38Å; T444-L447 WeakPolarHBondContact O-CB 3.49Å; T444-L447 PolarHBondContact O-N 3.47Å; L447-A449 VanDerWaalsContact C-N 3.3Å; L447-A449 PolarHBondContact O-N 2.98Å; L447-L450 WeakPolarHBondContact O-CB 3.49Å; L447-L450 PolarHBondContact O-N 3.3Å; L447-L450 VanDerWaalsContact O-N 3.15Å; L447-D451 PolarHBondContact O-N 3.32Å; L447-V469 HydrophobicContact CD2-CG1 4.07Å; L447-A472 HydrophobicContact CD2-CB 3.65Å; L447-A472 HydrophobicContact CG-CB 4.06Å; L447-Q473 HydrophobicContact CD2-CG 4.31Å; L447-L476 HydrophobicContact CD1-CD1 3.7Å
448	L	95.9	Very high	92.6	Very high	110 Å²	110	59.4 Å²	59.4	58%	0.576	33%	0.325	S	S	*	.	H	α-helix	trans	-61.9	-37.7	176.5	-65.1	173.8	0	0	0	112.3	T444 K445 D451 A452	T444-L448 WeakPolarHBondContact O-CG 3.5Å; T444-L448 PolarHBondContact O-N 3.15Å; K445-L448 PolarHBondContact O-N 2.6Å; L448-D451 PolarHBondContact O-N 2.99Å; L448-A452 PolarHBondContact O-N 3.45Å; L448-A452 VanDerWaalsContact O-N 3.15Å
449	A	95.6	Very high	92	Very high	40 Å²	40	61 Å²	61	33%	0.331	34%	0.336	S	S	.	.	H	α-helix	trans	-64.4	-39.6	175.3	0	0	0	0	0	112	V413 K445 Q446 L447 A452 V453	V413-A449 HydrophobicContact CG2-CB 4.01Å; K445-A449 WeakPolarHBondContact O-CB 3.35Å; K445-A449 PolarHBondContact O-N 3.19Å; Q446-A449 PolarHBondContact O-N 3.5Å; L447-A449 VanDerWaalsContact C-N 3.3Å; L447-A449 PolarHBondContact O-N 2.98Å; A449-A452 PolarHBondContact O-N 2.86Å; A449-V453 WeakPolarHBondContact O-CG2 3.39Å
450	L	94.7	Very high	91.4	Very high	0 Å²	0	68.3 Å²	68.3	0%	0	37%	0.368	C	S	.	.	H	α-helix	trans	-65.7	-40.4	174.7	-72.2	166	0	0	0	112	V410 V413 Q446 L447 A452 V453 R465 A468 V469	V410-L450 HydrophobicContact CG1-CD2 4.44Å; V410-L450 HydrophobicContact CG2-CD2 4.47Å; V413-L450 HydrophobicContact CB-CD2 4Å; V413-L450 HydrophobicContact CB-CG 4.28Å; V413-L450 HydrophobicContact CG1-CD1 3.94Å; V413-L450 HydrophobicContact CG1-CD2 3.94Å; V413-L450 HydrophobicContact CG1-CG 3.77Å; V413-L450 HydrophobicContact CG2-CD2 4.19Å; V413-L450 HydrophobicContact CG2-CG 4.32Å; Q446-L450 WeakPolarHBondContact O-CG 3.48Å; Q446-L450 PolarHBondContact O-N 2.96Å; L447-L450 WeakPolarHBondContact O-CB 3.49Å; L447-L450 PolarHBondContact O-N 3.3Å; L447-L450 VanDerWaalsContact O-N 3.15Å; L450-A452 PolarHBondContact O-N 3.44Å; L450-V453 WeakPolarHBondContact O-CB 3.25Å; L450-V453 PolarHBondContact O-N 3.14Å; L450-V453 VanDerWaalsContact O-N 3.1Å; L450-R465 HydrophobicContact CB-CG 4.44Å; L450-R465 HydrophobicContact CD2-CG 4.42Å; L450-R465 VanDerWaalsContact O-CD 3.28Å; L450-R465 WeakPolarHBondContact O-CD 3.47Å; L450-A468 HydrophobicContact CD1-CB 3.79Å; L450-A468 HydrophobicContact CD2-CB 3.67Å; L450-A468 HydrophobicContact CG-CB 4.41Å; L450-V469 HydrophobicContact CB-CG2 3.97Å; L450-V469 HydrophobicContact CD1-CG2 3.85Å; L450-V469 HydrophobicContact CG-CG2 4.49Å
451	D	93.4	Very high	91	Very high	108 Å²	108	64.8 Å²	64.8	58%	0.578	35%	0.351	S	S	*	.	H	α-helix	trans	-63.1	-32	177.6	-72.2	-22.7	0	0	0	112.4	L447 L448 V453	L447-D451 PolarHBondContact O-N 3.32Å; L448-D451 PolarHBondContact O-N 2.99Å; D451-V453 VanDerWaalsContact C-N 3.28Å; D451-V453 PolarHBondContact O-N 3.41Å
452	A	92.9	Very high	90.6	Very high	84 Å²	84	63.6 Å²	63.6	69%	0.694	35%	0.345	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.8	-11.6	176.1	0	0	0	0	0	114.2	L448 A449 L450 D454	L448-A452 PolarHBondContact O-N 3.45Å; L448-A452 VanDerWaalsContact O-N 3.15Å; A449-A452 PolarHBondContact O-N 2.86Å; L450-A452 PolarHBondContact O-N 3.44Å; A452-D454 PolarHBondContact O-N 2.95Å
453	V	91.6	Very high	90.2	Very high	11 Å²	11	63.7 Å²	63.7	7%	0.067	35%	0.352	C	S	.	.			trans	-75	113.7	177.4	-178.2	0	0	0	0	109.9	A409 V410 A449 L450 D451 P455 R465	A409-V453 HydrophobicContact CB-CG2 3.94Å; V410-V453 HydrophobicContact CG2-CG1 4.11Å; V410-V453 HydrophobicContact CG2-CG2 4.43Å; A449-V453 WeakPolarHBondContact O-CG2 3.39Å; L450-V453 WeakPolarHBondContact O-CB 3.25Å; L450-V453 PolarHBondContact O-N 3.14Å; L450-V453 VanDerWaalsContact O-N 3.1Å; D451-V453 VanDerWaalsContact C-N 3.28Å; D451-V453 PolarHBondContact O-N 3.41Å; V453-P455 VanDerWaalsContact O-CD 3.29Å; V453-P455 WeakPolarHBondContact O-CD 3.39Å; V453-R465 PolarHBondContact O-NH1 3.27Å
454	D	88.5	Confident	89.8	Confident	103 Å²	103	64.9 Å²	64.9	55%	0.551	36%	0.362	S	S	*	.			trans	-81.2	112.9	169.8	-178.6	8.2	0	0	0	110.6	S406 A452 Q456	S406-D454 VanDerWaalsContact CB-O 3.28Å; S406-D454 WeakPolarHBondContact CB-O 3.49Å; A452-D454 PolarHBondContact O-N 2.95Å; D454-Q456 PolarHBondContact O-N 3.25Å; D454-Q456 PolarHBondContact OD1-N 3.28Å
455	P	81.4	Confident	89.6	Confident	13 Å²	13	65.4 Å²	65.4	8%	0.084	36%	0.357	C	S	.	.			trans	-76.6	-4.5	179.4	32	-34.5	0	0	0	113.3	V453 G457 E458 C461 K462	V453-P455 VanDerWaalsContact O-CD 3.29Å; V453-P455 WeakPolarHBondContact O-CD 3.39Å; P455-G457 PolarHBondContact O-N 3.22Å; P455-E458 WeakPolarHBondContact O-CB 3.48Å; P455-E458 PolarHBondContact O-N 2.92Å; P455-C461 HydrophobicContact CB-CB 4Å; P455-K462 HydrophobicContact CB-CG 3.66Å; P455-K462 HydrophobicContact CG-CG 3.71Å
456	Q	80.8	Confident	89.4	Confident	130 Å²	130	68.3 Å²	68.3	61%	0.607	37%	0.37	S	S	*	.	T	Hydrogen-bonded Turn	trans	50.3	29.6	178.2	-61.7	-172.8	-10.1	0	0	114.4	H404 D454 E458	H404-Q456 PolarHBondContact CE1-OE1 3.44Å; H404-Q456 PolarHBondContact NE2-OE1 2.98Å; H404-Q456 VanDerWaalsContact NE2-OE1 3.15Å; D454-Q456 PolarHBondContact O-N 3.25Å; D454-Q456 PolarHBondContact OD1-N 3.28Å; Q456-E458 VanDerWaalsContact C-N 3.35Å
457	G	76.3	Confident	89.2	Confident	50 Å²	50	74.1 Å²	74.1	52%	0.515	40%	0.397	S	S	.	.	T	Hydrogen-bonded Turn	trans	83.8	-2.6	-178.5	0	0	0	0	0	115.7	P455 E459	P455-G457 PolarHBondContact O-N 3.22Å; G457-E459 PolarHBondContact O-N 2.93Å
458	E	83.3	Confident	89.1	Confident	69 Å²	69	72.6 Å²	72.6	32%	0.322	39%	0.389	S	S	.	.			trans	-74	115.3	177.8	-167.8	-175.1	-178.7	0	0	111.6	H407 P455 Q456 K460 C461 K462	H407-E458 IonicContact CD2-OE1 3.89Å; H407-E458 IonicContact CD2-OE2 3.27Å; H407-E458 PolarHBondContact CD2-OE2 3.11Å; H407-E458 VanDerWaalsContact CD2-OE2 3.27Å; H407-E458 IonicContact NE2-OE1 3.57Å; H407-E458 IonicContact NE2-OE2 3.55Å; P455-E458 WeakPolarHBondContact O-CB 3.48Å; P455-E458 PolarHBondContact O-N 2.92Å; Q456-E458 VanDerWaalsContact C-N 3.35Å; E458-K460 VanDerWaalsContact C-N 3.3Å; E458-K460 HydrophobicContact CG-CB 4.36Å; E458-K460 PolarHBondContact O-N 3.16Å; E458-C461 HydrophobicContact CB-CB 4.07Å; E458-C461 HydrophobicContact CG-CB 4.45Å; E458-C461 PolarHBondContact O-N 3.26Å; E458-K462 WeakPolarHBondContact O-CG 3.41Å; E458-K462 PolarHBondContact O-N 3.46Å
459	E	85.2	Confident	89.1	Confident	127 Å²	127	68.8 Å²	68.8	59%	0.593	37%	0.37	S	S	*	.	H	α-helix	trans	-62.4	-34.1	-177.2	-70.5	-55.4	132.5	0	0	113.5	G457 K462 A463	G457-E459 PolarHBondContact O-N 2.93Å; E459-K462 PolarHBondContact O-N 2.88Å; E459-K462 IonicContact OE1-NZ 3.7Å; E459-K462 PolarHBondContact OE1-NZ 2.94Å; E459-A463 WeakPolarHBondContact O-CB 3.49Å; E459-A463 PolarHBondContact O-N 3.3Å
460	K	84.9	Confident	89.1	Confident	152 Å²	152	73.5 Å²	73.5	66%	0.661	38%	0.383	S	S	*	.	H	α-helix	trans	-64.4	-42.7	176.3	-66.5	-179.7	-178.5	175.5	0	111.5	E458 A463 A464	E458-K460 VanDerWaalsContact C-N 3.3Å; E458-K460 HydrophobicContact CG-CB 4.36Å; E458-K460 PolarHBondContact O-N 3.16Å; K460-A463 PolarHBondContact O-N 3.14Å; K460-A464 WeakPolarHBondContact O-CB 3.21Å; K460-A464 PolarHBondContact O-N 3.36Å
461	C	86.4	Confident	89.1	Confident	0 Å²	0	74.7 Å²	74.7	0%	0	39%	0.389	C	S	.	.	H	α-helix	trans	-66.6	-42.3	177.4	-172.4	0	0	0	0	111.1	S406 H407 P455 E458 A463 A464 R465	S406-C461 VanDerWaalsContact CB-SG 3.5Å; S406-C461 PolarHBondContact OG-SG 2.99Å; H407-C461 WeakPolarHBondContact NE2-CA 3.16Å; H407-C461 PolarHBondContact NE2-N 3.33Å; H407-C461 VanDerWaalsContact NE2-N 3.16Å; P455-C461 HydrophobicContact CB-CB 4Å; E458-C461 HydrophobicContact CB-CB 4.07Å; E458-C461 HydrophobicContact CG-CB 4.45Å; E458-C461 PolarHBondContact O-N 3.26Å; C461-A463 PolarHBondContact O-N 2.87Å; C461-A464 PolarHBondContact O-N 3.39Å; C461-R465 VanDerWaalsContact O-CB 3.32Å; C461-R465 WeakPolarHBondContact O-CB 3.32Å; C461-R465 PolarHBondContact O-N 3.43Å
462	K	88.5	Confident	89.3	Confident	75 Å²	75	69.5 Å²	69.5	33%	0.326	36%	0.362	S	S	.	.	H	α-helix	trans	-58.1	-46.3	174.1	-68.5	177.7	-169	168.5	0	112.1	P455 E458 E459 K466	P455-K462 HydrophobicContact CB-CG 3.66Å; P455-K462 HydrophobicContact CG-CG 3.71Å; E458-K462 WeakPolarHBondContact O-CG 3.41Å; E458-K462 PolarHBondContact O-N 3.46Å; E459-K462 PolarHBondContact O-N 2.88Å; E459-K462 IonicContact OE1-NZ 3.7Å; E459-K462 PolarHBondContact OE1-NZ 2.94Å; K462-K466 WeakPolarHBondContact O-CB 3.38Å; K462-K466 PolarHBondContact O-N 3.31Å
463	A	88.8	Confident	89.4	Confident	49 Å²	49	70.6 Å²	70.6	41%	0.405	35%	0.353	S	S	.	.	H	α-helix	trans	-64.6	-46	179	0	0	0	0	0	111.7	E459 K460 C461 K466 Q467	E459-A463 WeakPolarHBondContact O-CB 3.49Å; E459-A463 PolarHBondContact O-N 3.3Å; K460-A463 PolarHBondContact O-N 3.14Å; C461-A463 PolarHBondContact O-N 2.87Å; A463-K466 PolarHBondContact O-N 3.1Å; A463-Q467 WeakPolarHBondContact O-CG 3.42Å; A463-Q467 PolarHBondContact O-N 3.4Å
464	A	88.9	Confident	89.5	Confident	25 Å²	25	74.2 Å²	74.2	21%	0.207	37%	0.371	C	S	.	.	H	α-helix	trans	-61.1	-45.5	177.5	0	0	0	0	0	111.8	V410 K460 C461 K466 Q467 A468	V410-A464 HydrophobicContact CG1-CB 4.15Å; K460-A464 WeakPolarHBondContact O-CB 3.21Å; K460-A464 PolarHBondContact O-N 3.36Å; C461-A464 PolarHBondContact O-N 3.39Å; A464-K466 PolarHBondContact O-N 2.94Å; A464-Q467 PolarHBondContact O-N 3.5Å; A464-A468 PolarHBondContact O-N 3.19Å
465	R	93.4	Very high	89.9	Confident	73 Å²	73	69.4 Å²	69.4	28%	0.275	35%	0.346	S	S	.	.	H	α-helix	trans	-59.1	-46.3	175	-173.3	-177	69.3	167.2	9.4	111.4	V410 L450 V453 C461 Q467 A468 V469	V410-R465 HydrophobicContact CG2-CB 4.12Å; L450-R465 HydrophobicContact CB-CG 4.44Å; L450-R465 HydrophobicContact CD2-CG 4.42Å; L450-R465 VanDerWaalsContact O-CD 3.28Å; L450-R465 WeakPolarHBondContact O-CD 3.47Å; V453-R465 PolarHBondContact O-NH1 3.27Å; C461-R465 VanDerWaalsContact O-CB 3.32Å; C461-R465 WeakPolarHBondContact O-CB 3.32Å; C461-R465 PolarHBondContact O-N 3.43Å; R465-Q467 VanDerWaalsContact C-N 3.32Å; R465-Q467 PolarHBondContact O-N 3.02Å; R465-A468 PolarHBondContact O-N 3.36Å; R465-V469 WeakPolarHBondContact O-CG2 3.47Å; R465-V469 PolarHBondContact O-N 2.71Å
466	K	93.6	Very high	90.4	Very high	163 Å²	163	70.1 Å²	70.1	71%	0.709	35%	0.349	S	S	*	.	H	α-helix	trans	-61.3	-40.1	177.9	-173.3	177.5	-178.8	178.6	0	112.1	K462 A463 A464 K470	K462-K466 WeakPolarHBondContact O-CB 3.38Å; K462-K466 PolarHBondContact O-N 3.31Å; A463-K466 PolarHBondContact O-N 3.1Å; A464-K466 PolarHBondContact O-N 2.94Å; K466-K470 PolarHBondContact O-N 3.21Å
467	Q	92.4	Very high	90.9	Very high	142 Å²	142	67.3 Å²	67.3	66%	0.664	34%	0.344	S	S	*	.	H	α-helix	trans	-65.5	-42.4	175.1	-73.6	179.1	-8	0	0	111.9	A463 A464 R465 K470 L471	A463-Q467 WeakPolarHBondContact O-CG 3.42Å; A463-Q467 PolarHBondContact O-N 3.4Å; A464-Q467 PolarHBondContact O-N 3.5Å; R465-Q467 VanDerWaalsContact C-N 3.32Å; R465-Q467 PolarHBondContact O-N 3.02Å; Q467-K470 PolarHBondContact O-N 2.93Å; Q467-L471 PolarHBondContact O-N 3.37Å
468	A	94.6	Very high	91.7	Very high	1 Å²	1	65.2 Å²	65.2	1%	0.008	32%	0.32	C	S	.	.	H	α-helix	trans	-63.7	-40.5	176.6	0	0	0	0	0	112.4	V410 L414 L450 A464 R465 L471 A472	V410-A468 HydrophobicContact CG1-CB 4.07Å; L414-A468 HydrophobicContact CD2-CB 3.8Å; L414-A468 HydrophobicContact CG-CB 4.27Å; L450-A468 HydrophobicContact CD1-CB 3.79Å; L450-A468 HydrophobicContact CD2-CB 3.67Å; L450-A468 HydrophobicContact CG-CB 4.41Å; A464-A468 PolarHBondContact O-N 3.19Å; R465-A468 PolarHBondContact O-N 3.36Å; A468-L471 WeakPolarHBondContact O-CB 3.42Å; A468-L471 PolarHBondContact O-N 3.4Å; A468-A472 PolarHBondContact O-N 3.4Å
469	V	96.4	Very high	92.1	Very high	30 Å²	30	62 Å²	62	18%	0.182	31%	0.305	C	S	.	.	H	α-helix	trans	-60.9	-46.7	173.7	170	0	0	0	0	110.5	L447 L450 R465 L471 A472 Q473	L447-V469 HydrophobicContact CD2-CG1 4.07Å; L450-V469 HydrophobicContact CB-CG2 3.97Å; L450-V469 HydrophobicContact CD1-CG2 3.85Å; L450-V469 HydrophobicContact CG-CG2 4.49Å; R465-V469 WeakPolarHBondContact O-CG2 3.47Å; R465-V469 PolarHBondContact O-N 2.71Å; V469-L471 VanDerWaalsContact C-N 3.29Å; V469-L471 PolarHBondContact O-N 2.96Å; V469-A472 PolarHBondContact O-N 3.04Å; V469-Q473 HydrophobicContact CG1-CG 4.44Å; V469-Q473 WeakPolarHBondContact O-CG 3.29Å; V469-Q473 PolarHBondContact O-N 3.19Å
470	K	95.3	Very high	92.2	Very high	139 Å²	139	58.1 Å²	58.1	60%	0.604	29%	0.289	S	S	*	.	H	α-helix	trans	-61.4	-39.4	178.2	-164	177.7	-175.6	-177.8	0	111.7	K466 Q467 N474	K466-K470 PolarHBondContact O-N 3.21Å; Q467-K470 PolarHBondContact O-N 2.93Å; K470-N474 WeakPolarHBondContact O-CB 3.41Å; K470-N474 PolarHBondContact O-N 3.44Å; K470-N474 PolarHBondContact O-ND2 3.21Å; K470-N474 PolarHBondContact O-OD1 3.34Å
471	L	95.6	Very high	92.3	Very high	24 Å²	24	51.8 Å²	51.8	13%	0.126	26%	0.262	C	S	.	.	H	α-helix	trans	-63.1	-48.2	174.8	175.5	66	0	0	0	111.6	L389 L414 L417 Q467 A468 V469 Q473 N474 I475	L389-L471 HydrophobicContact CD1-CD2 4.04Å; L389-L471 HydrophobicContact CD2-CD2 3.78Å; L389-L471 HydrophobicContact CG-CD2 4.47Å; L414-L471 HydrophobicContact CD2-CD2 3.72Å; L417-L471 HydrophobicContact CB-CD2 4.44Å; L417-L471 HydrophobicContact CD1-CD2 4.12Å; L417-L471 HydrophobicContact CD1-CG 4.42Å; Q467-L471 PolarHBondContact O-N 3.37Å; A468-L471 WeakPolarHBondContact O-CB 3.42Å; A468-L471 PolarHBondContact O-N 3.4Å; V469-L471 VanDerWaalsContact C-N 3.29Å; V469-L471 PolarHBondContact O-N 2.96Å; L471-Q473 VanDerWaalsContact C-N 3.32Å; L471-Q473 PolarHBondContact O-N 3.44Å; L471-N474 WeakPolarHBondContact O-CB 3.45Å; L471-N474 PolarHBondContact O-N 3.14Å; L471-N474 VanDerWaalsContact O-N 3.17Å; L471-I475 HydrophobicContact CD1-CD1 4.09Å; L471-I475 HydrophobicContact CD1-CG1 4.32Å; L471-I475 HydrophobicContact CG-CD1 3.94Å; L471-I475 VanDerWaalsContact O-CG1 3.31Å; L471-I475 WeakPolarHBondContact O-CG1 3.41Å; L471-I475 PolarHBondContact O-N 3.16Å
472	A	96.4	Very high	92.1	Very high	0 Å²	0	54 Å²	54	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-59.5	-43.1	177.6	0	0	0	0	0	112	L417 L447 A468 V469 I475 L476	L417-A472 HydrophobicContact CD1-CB 4.03Å; L417-A472 HydrophobicContact CD2-CB 3.8Å; L447-A472 HydrophobicContact CD2-CB 3.65Å; L447-A472 HydrophobicContact CG-CB 4.06Å; A468-A472 PolarHBondContact O-N 3.4Å; V469-A472 PolarHBondContact O-N 3.04Å; A472-I475 PolarHBondContact O-N 3.45Å; A472-L476 PolarHBondContact O-N 3.32Å
473	Q	94.6	Very high	91.6	Very high	107 Å²	107	50.6 Å²	50.6	50%	0.5	26%	0.257	S	S	.	.	H	α-helix	trans	-63.2	-40	174.6	-72.2	174.8	-19.8	0	0	112.4	L447 V469 L471 L476 S477	L447-Q473 HydrophobicContact CD2-CG 4.31Å; V469-Q473 HydrophobicContact CG1-CG 4.44Å; V469-Q473 WeakPolarHBondContact O-CG 3.29Å; V469-Q473 PolarHBondContact O-N 3.19Å; L471-Q473 VanDerWaalsContact C-N 3.32Å; L471-Q473 PolarHBondContact O-N 3.44Å; Q473-L476 PolarHBondContact O-N 3.16Å; Q473-S477 WeakPolarHBondContact O-CB 3.28Å; Q473-S477 PolarHBondContact O-N 3.32Å
474	N	94.6	Very high	90.7	Very high	86 Å²	86	50.1 Å²	50.1	46%	0.46	25%	0.247	S	C	.	.	H	α-helix	trans	-64.7	-40.5	175.2	-71	-15.9	0	0	0	111.7	K470 L471 S477 Y478	K470-N474 WeakPolarHBondContact O-CB 3.41Å; K470-N474 PolarHBondContact O-N 3.44Å; K470-N474 PolarHBondContact O-ND2 3.21Å; K470-N474 PolarHBondContact O-OD1 3.34Å; L471-N474 WeakPolarHBondContact O-CB 3.45Å; L471-N474 PolarHBondContact O-N 3.14Å; L471-N474 VanDerWaalsContact O-N 3.17Å; N474-S477 PolarHBondContact O-N 3.44Å; N474-Y478 WeakPolarHBondContact O-CB 3.29Å; N474-Y478 PolarHBondContact O-N 2.94Å
475	I	95.9	Very high	89.4	Confident	2 Å²	2	53.6 Å²	53.6	1%	0.01	26%	0.259	C	S	.	.	H	α-helix	trans	-65.6	-41.8	177.2	-62.6	160.9	0	0	0	110.4	L417 Q421 V424 L443 L471 A472 Y478 L479	L417-I475 HydrophobicContact CB-CD1 4.21Å; L417-I475 HydrophobicContact CD2-CD1 4.22Å; Q421-I475 HydrophobicContact CB-CD1 3.9Å; Q421-I475 HydrophobicContact CB-CG1 4.23Å; Q421-I475 HydrophobicContact CB-CG2 4.49Å; Q421-I475 HydrophobicContact CG-CD1 4.22Å; Q421-I475 HydrophobicContact CG-CG1 4.06Å; V424-I475 HydrophobicContact CB-CG2 4.27Å; V424-I475 HydrophobicContact CG1-CG2 4.29Å; V424-I475 HydrophobicContact CG2-CG2 3.91Å; L443-I475 HydrophobicContact CD1-CG2 3.87Å; L443-I475 HydrophobicContact CD2-CB 4Å; L443-I475 HydrophobicContact CD2-CG2 3.69Å; L443-I475 HydrophobicContact CG-CG2 4.43Å; L471-I475 HydrophobicContact CD1-CD1 4.09Å; L471-I475 HydrophobicContact CD1-CG1 4.32Å; L471-I475 HydrophobicContact CG-CD1 3.94Å; L471-I475 VanDerWaalsContact O-CG1 3.31Å; L471-I475 WeakPolarHBondContact O-CG1 3.41Å; L471-I475 PolarHBondContact O-N 3.16Å; A472-I475 PolarHBondContact O-N 3.45Å; I475-Y478 PolarHBondContact O-N 2.71Å; I475-L479 WeakPolarHBondContact O-CB 3.49Å; I475-L479 PolarHBondContact O-N 2.99Å
476	L	93.5	Very high	87.9	Confident	29 Å²	29	51.9 Å²	51.9	15%	0.152	25%	0.253	C	S	.	.	H	α-helix	trans	-59.4	-52.1	173	-82.8	168	0	0	0	111.6	E440 L443 L447 A472 Q473 Y478 L479 D480	E440-L476 HydrophobicContact CG-CD2 4.17Å; L443-L476 HydrophobicContact CB-CD1 4.17Å; L443-L476 HydrophobicContact CB-CD2 3.61Å; L443-L476 HydrophobicContact CB-CG 3.7Å; L443-L476 HydrophobicContact CD1-CD2 3.53Å; L443-L476 HydrophobicContact CD1-CG 3.74Å; L443-L476 HydrophobicContact CG-CD2 4.18Å; L443-L476 HydrophobicContact CG-CG 4.23Å; L447-L476 HydrophobicContact CD1-CD1 3.7Å; A472-L476 PolarHBondContact O-N 3.32Å; Q473-L476 PolarHBondContact O-N 3.16Å; L476-Y478 PolarHBondContact O-N 3.23Å; L476-L479 WeakPolarHBondContact O-CB 3.32Å; L476-L479 PolarHBondContact O-N 2.9Å; L476-L479 VanDerWaalsContact O-N 3.07Å; L476-D480 PolarHBondContact O-N 3.37Å
477	S	91	Very high	86.4	Confident	71 Å²	71	47 Å²	47	50%	0.497	23%	0.233	S	C	.	.	H	α-helix	trans	-59.6	-34.3	178.8	179	0	0	0	0	112.3	Q473 N474 D480 L481	Q473-S477 WeakPolarHBondContact O-CB 3.28Å; Q473-S477 PolarHBondContact O-N 3.32Å; N474-S477 PolarHBondContact O-N 3.44Å; S477-D480 WeakPolarHBondContact O-CB 3.45Å; S477-L481 WeakPolarHBondContact O-CB 3.49Å; S477-L481 PolarHBondContact O-N 3.21Å
478	Y	92.8	Very high	84.7	Confident	6 Å²	6	42.3 Å²	42.3	2%	0.024	21%	0.209	C	C	.	.	H	α-helix	trans	-72.1	-40.2	174.9	178.8	-112.4	0	0	0	112.8	I378 E379 T382 V424 L425 N474 I475 L476 D480 L481 K482	I378-Y478 HydrophobicContact CG2-CD2 4.01Å; E379-Y478 HydrophobicContact CB-CE2 4.4Å; E379-Y478 HydrophobicContact CG-CE2 3.78Å; T382-Y478 HydrophobicContact CG2-CD1 3.64Å; T382-Y478 HydrophobicContact CG2-CD2 4.3Å; T382-Y478 HydrophobicContact CG2-CE1 3.81Å; T382-Y478 HydrophobicContact CG2-CE2 4.47Å; T382-Y478 HydrophobicContact CG2-CG 3.88Å; T382-Y478 WeakPolarHBondContact OG1-CD2 3.47Å; V424-Y478 HydrophobicContact CG1-CD1 3.66Å; V424-Y478 HydrophobicContact CG1-CE1 4.09Å; L425-Y478 HydrophobicContact CD2-CE1 4.1Å; N474-Y478 WeakPolarHBondContact O-CB 3.29Å; N474-Y478 PolarHBondContact O-N 2.94Å; I475-Y478 PolarHBondContact O-N 2.71Å; L476-Y478 PolarHBondContact O-N 3.23Å; Y478-D480 VanDerWaalsContact C-N 3.32Å; Y478-L481 PolarHBondContact O-N 3.34Å; Y478-K482 VanDerWaalsContact CE1-CE 3.4Å; Y478-K482 WeakPolarHBondContact O-CB 3.44Å; Y478-K482 PolarHBondContact O-N 3.06Å; Y478-K482 WeakPolarHBondContact OH-CE 3.31Å; Y478-K482 PolarHBondContact OH-NZ 3.42Å; Y478-K482 VanDerWaalsContact OH-NZ 3.16Å
479	L	92.3	Very high	84.2	Confident	0 Å²	0	44.4 Å²	44.4	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-60.3	-44.4	173.7	178.6	62.2	0	0	0	110.8	V424 F427 Y436 L439 L443 I475 L476 K482 S483	V424-L479 HydrophobicContact CG1-CB 3.96Å; V424-L479 HydrophobicContact CG1-CD1 4.14Å; V424-L479 HydrophobicContact CG2-CB 4.49Å; V424-L479 HydrophobicContact CG2-CD1 4.3Å; V424-L479 HydrophobicContact CG2-CD2 4.48Å; F427-L479 HydrophobicContact CB-CD1 4.46Å; F427-L479 HydrophobicContact CD1-CD1 3.68Å; F427-L479 HydrophobicContact CE1-CD1 4.04Å; F427-L479 HydrophobicContact CG-CD1 3.99Å; Y436-L479 HydrophobicContact CD2-CD1 4.01Å; Y436-L479 HydrophobicContact CD2-CD2 4.22Å; Y436-L479 HydrophobicContact CD2-CG 3.85Å; Y436-L479 HydrophobicContact CE2-CD1 4.35Å; Y436-L479 HydrophobicContact CE2-CD2 4.17Å; Y436-L479 HydrophobicContact CE2-CG 3.73Å; L439-L479 HydrophobicContact CB-CD2 3.69Å; L439-L479 HydrophobicContact CD1-CD1 4.14Å; L443-L479 HydrophobicContact CD1-CD2 4.18Å; I475-L479 WeakPolarHBondContact O-CB 3.49Å; I475-L479 PolarHBondContact O-N 2.99Å; L476-L479 WeakPolarHBondContact O-CB 3.32Å; L476-L479 PolarHBondContact O-N 2.9Å; L476-L479 VanDerWaalsContact O-N 3.07Å; L479-K482 PolarHBondContact O-N 3.32Å; L479-S483 WeakPolarHBondContact O-CB 3.36Å; L479-S483 PolarHBondContact O-N 3.33Å; L479-S483 PolarHBondContact O-OG 3.09Å
480	D	87	Confident	83.6	Confident	47 Å²	47	45.2 Å²	45.2	25%	0.251	22%	0.221	S	C	.	.	H	α-helix	trans	-55	-52.5	171.6	-84.7	-51.4	0	0	0	111.7	R431 Y436 L476 S477 Y478 K482 S483 D484	R431-D480 IonicContact CZ-OD1 3.44Å; R431-D480 IonicContact NE-OD1 2.73Å; R431-D480 PolarHBondContact NE-OD1 3.47Å; R431-D480 IonicContact NH2-OD1 2.56Å; R431-D480 PolarHBondContact NH2-OD1 3.33Å; Y436-D480 PolarHBondContact OH-OD1 3.26Å; L476-D480 PolarHBondContact O-N 3.37Å; S477-D480 WeakPolarHBondContact O-CB 3.45Å; Y478-D480 VanDerWaalsContact C-N 3.32Å; D480-K482 VanDerWaalsContact C-N 3.29Å; D480-K482 PolarHBondContact O-N 3.25Å; D480-S483 PolarHBondContact O-N 3.27Å; D480-S483 PolarHBondContact O-OG 3.4Å; D480-D484 PolarHBondContact O-N 3Å; D480-D484 VanDerWaalsContact O-N 3.15Å
481	L	86.1	Confident	82.9	Confident	19 Å²	19	39.9 Å²	39.9	10%	0.099	20%	0.2	C	C	.	.	H	α-helix	trans	-60.4	-37.7	-179.3	-177.1	150.4	0	0	0	112.5	R375 I378 S477 Y478 D484	R375-L481 HydrophobicContact CG-CD1 4.13Å; R375-L481 HydrophobicContact CG-CD2 4.5Å; R375-L481 HydrophobicContact CG-CG 4.46Å; I378-L481 HydrophobicContact CB-CD1 4.41Å; I378-L481 HydrophobicContact CD1-CD1 3.9Å; I378-L481 HydrophobicContact CG2-CD1 4.1Å; S477-L481 WeakPolarHBondContact O-CB 3.49Å; S477-L481 PolarHBondContact O-N 3.21Å; Y478-L481 PolarHBondContact O-N 3.34Å; L481-D484 WeakPolarHBondContact O-CB 3.47Å; L481-D484 PolarHBondContact O-N 3.48Å
482	K	83.3	Confident	82.2	Confident	47 Å²	47	40.9 Å²	40.9	20%	0.204	21%	0.205	C	C	.	.	H	α-helix	trans	-75.4	-32.4	178.8	-167.7	179.8	-59	-173.3	0	112.9	V424 L425 F427 Y478 L479 D480 D484	V424-K482 PolarHBondContact O-NZ 3.23Å; L425-K482 PolarHBondContact O-NZ 3.5Å; F427-K482 HydrophobicContact CD1-CD 4.21Å; F427-K482 HydrophobicContact CD1-CG 4.49Å; F427-K482 WeakPolarHBondContact O-CD 3.45Å; Y478-K482 VanDerWaalsContact CE1-CE 3.4Å; Y478-K482 WeakPolarHBondContact O-CB 3.44Å; Y478-K482 PolarHBondContact O-N 3.06Å; Y478-K482 WeakPolarHBondContact OH-CE 3.31Å; Y478-K482 PolarHBondContact OH-NZ 3.42Å; Y478-K482 VanDerWaalsContact OH-NZ 3.16Å; L479-K482 PolarHBondContact O-N 3.32Å; D480-K482 VanDerWaalsContact C-N 3.29Å; D480-K482 PolarHBondContact O-N 3.25Å; K482-D484 PolarHBondContact O-N 3.28Å
483	S	76.8	Confident	81.3	Confident	3 Å²	3	43.4 Å²	43.4	2%	0.021	22%	0.217	C	C	.	.	H	α-helix	trans	-74	-8.4	174.1	74.5	0	0	0	0	113.4	G429 R431 Y436 L479 D480	G429-S483 WeakPolarHBondContact O-CA 3.42Å; R431-S483 VanDerWaalsContact CG-OG 3.22Å; R431-S483 WeakPolarHBondContact CG-OG 3.37Å; Y436-S483 WeakPolarHBondContact CE2-OG 3.47Å; L479-S483 WeakPolarHBondContact O-CB 3.36Å; L479-S483 PolarHBondContact O-N 3.33Å; L479-S483 PolarHBondContact O-OG 3.09Å; D480-S483 PolarHBondContact O-N 3.27Å; D480-S483 PolarHBondContact O-OG 3.4Å
484	D	71.4	Confident	80.4	Confident	38 Å²	38	39.2 Å²	39.2	20%	0.203	20%	0.199	C	C	.	.	S	Bend	trans	-85.8	118.2	177.1	-166.9	24.7	0	0	0	110.2	K179 R375 D480 L481 K482 W486	K179-D484 WeakPolarHBondContact CE-OD1 3.28Å; R375-D484 IonicContact CZ-OD2 3.01Å; R375-D484 IonicContact NH1-OD2 3.2Å; R375-D484 PolarHBondContact NH1-OD2 3.11Å; R375-D484 IonicContact NH2-OD2 2.69Å; R375-D484 PolarHBondContact NH2-OD2 3.02Å; D480-D484 PolarHBondContact O-N 3Å; D480-D484 VanDerWaalsContact O-N 3.15Å; L481-D484 WeakPolarHBondContact O-CB 3.47Å; L481-D484 PolarHBondContact O-N 3.48Å; K482-D484 PolarHBondContact O-N 3.28Å; D484-W486 PolarHBondContact O-N 2.96Å
485	E	59.9	Low	79.4	Confident	98 Å²	98	35.9 Å²	35.9	46%	0.458	18%	0.18	S	C	.	.			trans	-78.2	61.2	-178.3	-63.8	161.1	159	0	0	110.2	K179	K179-E485 HydrophobicContact CD-CB 4.47Å; K179-E485 IonicContact NZ-OE2 3.31Å; K179-E485 PolarHBondContact NZ-OE2 2.88Å
486	W	62.3	Low	78.1	Confident	37 Å²	37	38.5 Å²	38.5	14%	0.14	19%	0.193	C	C	.	.			trans	-80.7	128.9	179.8	-178.3	83.1	0	0	0	110.8	T176 E371 A372 R375 D484 Y488	T176-W486 PolarHBondContact O-NE1 2.79Å; E371-W486 HydrophobicContact CG-CZ2 4.35Å; A372-W486 VanDerWaalsContact CA-CH2 3.46Å; A372-W486 HydrophobicContact CB-CH2 3.55Å; A372-W486 HydrophobicContact CB-CZ2 4.35Å; A372-W486 HydrophobicContact CB-CZ3 4.31Å; R375-W486 VanDerWaalsContact CZ-CB 3.42Å; D484-W486 PolarHBondContact O-N 2.96Å; W486-Y488 AromaticContact CH2-CD1 3.27Å; W486-Y488 HydrophobicContact CH2-CD1 3.27Å; W486-Y488 AromaticContact CH2-CE1 3.21Å; W486-Y488 HydrophobicContact CH2-CE1 3.21Å; W486-Y488 HydrophobicContact CH2-CG 4.07Å; W486-Y488 AromaticContact CH2-CZ 3.95Å; W486-Y488 HydrophobicContact CZ2-CD1 4.22Å; W486-Y488 HydrophobicContact CZ2-CE1 4.46Å; W486-Y488 AromaticContact CZ3-CD1 3.67Å; W486-Y488 HydrophobicContact CZ3-CD1 3.67Å; W486-Y488 HydrophobicContact CZ3-CD2 4.36Å; W486-Y488 AromaticContact CZ3-CE1 3.33Å; W486-Y488 HydrophobicContact CZ3-CE1 3.33Å; W486-Y488 HydrophobicContact CZ3-CE2 4.06Å; W486-Y488 HydrophobicContact CZ3-CG 4.19Å; W486-Y488 AromaticContact CZ3-CZ 3.54Å
487	E	62.6	Low	76.8	Confident	62 Å²	62	39.3 Å²	39.3	29%	0.29	20%	0.196	S	C	.	.			trans	-127	144.5	178.6	-65.7	-175.7	-143.3	0	0	111	G181 G182 R190	G181-E487 WeakPolarHBondContact CA-OE1 3.45Å; G182-E487 WeakPolarHBondContact CA-OE2 3.43Å; G182-E487 PolarHBondContact N-OE1 3.19Å; G182-E487 PolarHBondContact N-OE2 3.37Å; R190-E487 PolarHBondContact NH2-O 3.12Å
488	Y	56.6	Low	75.5	Confident	43 Å²	43	36.4 Å²	36.4	17%	0.169	17%	0.169	C	C	.	.			trans	-64	0	176	-56.8	-82.3	0	0	0	112.7	R187 R190 I317 E321 A372 W486	R187-Y488 WeakPolarHBondContact CD-O 3.46Å; R187-Y488 PolarHBondContact NH1-O 3.02Å; R187-Y488 VanDerWaalsContact NH1-O 3.08Å; R190-Y488 PolarHBondContact NH2-OXT 3.15Å; I317-Y488 HydrophobicContact CD1-CD1 3.61Å; I317-Y488 HydrophobicContact CD1-CE1 3.65Å; I317-Y488 HydrophobicContact CG1-CD1 4.16Å; I317-Y488 HydrophobicContact CG1-CE1 4.45Å; I317-Y488 HydrophobicContact CG2-CD1 3.69Å; I317-Y488 HydrophobicContact CG2-CD2 4.28Å; I317-Y488 HydrophobicContact CG2-CE1 3.74Å; I317-Y488 HydrophobicContact CG2-CE2 4.35Å; I317-Y488 HydrophobicContact CG2-CG 3.97Å; E321-Y488 HydrophobicContact CG-CE2 4.37Å; E321-Y488 WeakPolarHBondContact OE1-CE2 3.22Å; E321-Y488 PolarHBondContact OE1-OH 2.93Å; A372-Y488 HydrophobicContact CB-CD1 4.27Å; A372-Y488 HydrophobicContact CB-CE1 3.57Å; W486-Y488 AromaticContact CH2-CD1 3.27Å; W486-Y488 HydrophobicContact CH2-CD1 3.27Å; W486-Y488 AromaticContact CH2-CE1 3.21Å; W486-Y488 HydrophobicContact CH2-CE1 3.21Å; W486-Y488 HydrophobicContact CH2-CG 4.07Å; W486-Y488 AromaticContact CH2-CZ 3.95Å; W486-Y488 HydrophobicContact CZ2-CD1 4.22Å; W486-Y488 HydrophobicContact CZ2-CE1 4.46Å; W486-Y488 AromaticContact CZ3-CD1 3.67Å; W486-Y488 HydrophobicContact CZ3-CD1 3.67Å; W486-Y488 HydrophobicContact CZ3-CD2 4.36Å; W486-Y488 AromaticContact CZ3-CE1 3.33Å; W486-Y488 HydrophobicContact CZ3-CE1 3.33Å; W486-Y488 HydrophobicContact CZ3-CE2 4.06Å; W486-Y488 HydrophobicContact CZ3-CG 4.19Å; W486-Y488 AromaticContact CZ3-CZ 3.54Å

Retrieved 488 of 488 residues in 577.3 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).