A0A096NQJ1_PAPAN Loading...

Sorting nexin-8

May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network.

AlphaFold DB , UniProt , Accession A0A096NQJ1, Species PAPAN (Papio anubis, Olive baboon), Gene SNX8, Length 465 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	36.3	Very low	37.5	Very low	238 Å²	238	145.6 Å²	145.6	100%	1.172	84%	0.843	S	S	*	*				0	150.7	0	-76.4	163	159.5	0	0	108.7
2	T	38.3	Very low	37	Very low	136 Å²	136	142.3 Å²	142.3	83%	0.834	85%	0.845	S	S	*	*			trans	3.3	126.9	156.6	52.5	0	0	0	0	118
3	G	31.9	Very low	36.3	Very low	74 Å²	74	138.5 Å²	138.5	76%	0.763	84%	0.839	S	S	*	*			cis	96.2	100.9	-0.6	0	0	0	0	0	115
4	R	34.7	Very low	36	Very low	247 Å²	247	139.1 Å²	139.1	93%	0.932	84%	0.843	S	S	*	*			trans	-167.9	158.2	150.4	-130.4	176.6	179.8	160.4	0.4	111.3
5	A	39.1	Very low	35.5	Very low	88 Å²	88	134.7 Å²	134.7	73%	0.727	84%	0.837	S	S	*	*			trans	-129.8	160	167.4	0	0	0	0	0	108.9
6	M	36.2	Very low	35	Very low	177 Å²	177	132 Å²	132	87%	0.872	83%	0.832	S	S	*	*			trans	-167.3	155.6	150.8	-113.9	167.9	-179.4	0	0	113.7
7	D	36	Very low	34.6	Very low	154 Å²	154	130.1 Å²	130.1	82%	0.824	83%	0.831	S	S	*	*			trans	-75.6	-179.6	-166.2	-69.4	-80.4	0	0	0	117
8	P	47.5	Very low	34.2	Very low	103 Å²	103	127.1 Å²	127.1	67%	0.669	82%	0.82	S	S	*	*			trans	-115.3	177.9	-161.9	43.7	-34.9	0	0	0	116.3
9	L	35.2	Very low	33.9	Very low	160 Å²	160	130.2 Å²	130.2	84%	0.838	82%	0.823	S	S	*	*			trans	69.2	153.1	168.4	-63.3	169	0	0	0	115.2
10	P	41.5	Very low	33.6	Very low	125 Å²	125	127.7 Å²	127.7	81%	0.812	81%	0.814	S	S	*	*				-133.4	175.2	78.7	39.8	-27.6	0	0	0	114.6
11	A	35.8	Very low	33.4	Very low	100 Å²	100	130.2 Å²	130.2	83%	0.826	82%	0.816	S	S	*	*			trans	-103.5	159.9	163.9	0	0	0	0	0	110.7
12	A	31.1	Very low	33	Very low	105 Å²	105	122.7 Å²	122.7	87%	0.868	79%	0.791	S	S	*	*			trans	-146.2	154.4	171.9	0	0	0	0	0	110.2
13	A	28.5	Very low	32.5	Very low	93 Å²	93	123.6 Å²	123.6	77%	0.769	79%	0.791	S	S	*	*			trans	-157.7	169.7	-171.9	0	0	0	0	0	113.3
14	V	32.3	Very low	32.4	Very low	147 Å²	147	128.5 Å²	128.5	89%	0.891	79%	0.794	S	S	*	*			trans	77.1	137.9	164.1	-168.1	0	0	0	0	118.1	A16	V14-A16 HydrophobicContact CG1-CB 4.3Å
15	G	28.6	Very low	32.1	Very low	74 Å²	74	125.2 Å²	125.2	76%	0.763	79%	0.789	S	S	*	*			trans	152.9	96.6	174.1	0	0	0	0	0	109.1
16	A	27.2	Very low	31.5	Very low	91 Å²	91	130.1 Å²	130.1	75%	0.752	80%	0.797	S	S	*	*			cis	91.8	146.7	22.7	0	0	0	0	0	115	V14	V14-A16 HydrophobicContact CG1-CB 4.3Å
17	A	28.1	Very low	31.3	Very low	99 Å²	99	128.9 Å²	128.9	82%	0.818	79%	0.794	S	S	*	*			trans	74	130.2	-163.3	0	0	0	0	0	114.4
18	A	28.2	Very low	31.3	Very low	76 Å²	76	126.6 Å²	126.6	63%	0.628	79%	0.788	S	S	*	*			cis	89.9	150	37.6	0	0	0	0	0	112.8
19	E	27.4	Very low	31	Very low	187 Å²	187	127.9 Å²	127.9	87%	0.874	80%	0.796	S	S	*	*			cis	-168.8	166.6	-10.7	-109.5	140.8	-139.5	0	0	107
20	A	28.9	Very low	30.7	Very low	79 Å²	79	125.1 Å²	125.1	65%	0.653	80%	0.797	S	S	*	*			cis	-135.5	-122	-7.5	0	0	0	0	0	109.3
21	E	27.9	Very low	30.1	Very low	181 Å²	181	123.8 Å²	123.8	85%	0.846	80%	0.796	S	S	*	*			cis	-168.9	159.2	-7.6	-143.6	148.3	-117.3	0	0	110.7
22	A	28.5	Very low	29.7	Very low	80 Å²	80	126.3 Å²	126.3	66%	0.661	80%	0.796	S	S	*	*			trans	48.4	150.6	150.4	0	0	0	0	0	123.7
23	D	27.3	Very low	29.5	Very low	155 Å²	155	129.5 Å²	129.5	83%	0.829	79%	0.793	S	S	*	*			cis	-161.6	-169.8	-12.9	-107.8	-22.9	0	0	0	113.7
24	E	30.6	Very low	29.8	Very low	178 Å²	178	130.7 Å²	130.7	83%	0.832	79%	0.793	S	S	*	*			trans	-69.3	159.7	-165.8	-49.7	174.6	124.4	0	0	119.6
25	E	27.6	Very low	29.8	Very low	177 Å²	177	130 Å²	130	83%	0.827	79%	0.789	S	S	*	*				179.2	112.1	129.8	-100.2	-178.7	171.6	0	0	109.7
26	E	27.6	Very low	29.8	Very low	191 Å²	191	132.5 Å²	132.5	89%	0.893	79%	0.791	S	S	*	*				83.7	143	101.7	-77.1	-145.9	151.7	0	0	118
27	D	31	Very low	29.9	Very low	151 Å²	151	137.4 Å²	137.4	81%	0.807	80%	0.799	S	S	*	*			trans	-154.4	127.4	-171.3	171	44.7	0	0	0	111.9
28	P	36.4	Very low	29.8	Very low	107 Å²	107	137.6 Å²	137.6	70%	0.695	80%	0.8	S	S	*	*			trans	-154.5	-179.9	137.9	39	-22.2	0	0	0	115
29	P	41.5	Very low	29.8	Very low	129 Å²	129	141.8 Å²	141.8	84%	0.838	81%	0.811	S	S	*	*			cis	-126.8	-166.7	-16.8	22.6	2.7	0	0	0	113.4
30	A	28.9	Very low	29.9	Very low	103 Å²	103	141.1 Å²	141.1	85%	0.851	81%	0.807	S	S	*	*			trans	-116.7	-169.3	-160.9	0	0	0	0	0	117.8
31	A	28.6	Very low	30	Very low	97 Å²	97	143.7 Å²	143.7	80%	0.802	82%	0.817	S	S	*	*			trans	105.7	136.6	-177.9	0	0	0	0	0	113.9
32	D	28.3	Very low	30	Very low	152 Å²	152	143.6 Å²	143.6	81%	0.813	82%	0.817	S	S	*	*			cis	-138.3	179.6	16.5	-145.3	-23.9	0	0	0	114
33	Q	27	Very low	30	Very low	173 Å²	173	144.2 Å²	144.2	81%	0.808	82%	0.822	S	S	*	*			trans	-82.6	-177.9	-167	-54.3	-176	12.5	0	0	115.2
34	P	34.1	Very low	30.1	Very low	118 Å²	118	144 Å²	144	77%	0.766	82%	0.819	S	S	*	*			cis	-136.3	-171	1.9	42.4	-22.4	0	0	0	117.1
35	T	31.8	Very low	30	Very low	131 Å²	131	141.3 Å²	141.3	80%	0.804	82%	0.815	S	S	*	*			trans	-82.4	160.4	-173.6	43.9	0	0	0	0	117
36	P	29.4	Very low	30.1	Very low	127 Å²	127	141.3 Å²	141.3	83%	0.825	82%	0.815	S	S	*	*			trans	-120.2	177.5	134.5	37.1	-30.8	0	0	0	113.1
37	Q	28.1	Very low	30.2	Very low	195 Å²	195	140.9 Å²	140.9	91%	0.911	81%	0.813	S	S	*	*			trans	-91.5	160.5	-161	-66.4	165.8	-32.5	0	0	115.4
38	A	26.5	Very low	30.1	Very low	102 Å²	102	138.5 Å²	138.5	84%	0.843	81%	0.814	S	S	*	*			trans	-80.8	157.4	179.5	0	0	0	0	0	114
39	I	29.2	Very low	29.8	Very low	165 Å²	165	138.2 Å²	138.2	85%	0.846	82%	0.821	S	S	*	*			trans	-132.6	131.7	170.3	-62.3	177.8	0	0	0	108.1
40	E	29.6	Very low	29.3	Very low	172 Å²	172	136 Å²	136	80%	0.804	81%	0.813	S	S	*	*			trans	-78.6	151.3	-179.1	-67	-173.7	136.7	0	0	113.3
41	P	30.6	Very low	29.7	Very low	133 Å²	133	136.9 Å²	136.9	86%	0.864	81%	0.81	S	S	*	*			trans	-81.1	120.1	-179.9	31.9	-33.7	0	0	0	112.5
42	Q	27.2	Very low	30.1	Very low	180 Å²	180	137.8 Å²	137.8	84%	0.841	81%	0.811	S	S	*	*			trans	-106	138.5	167.4	-67.1	-165.9	-2.1	0	0	111.7
43	A	28.3	Very low	30.7	Very low	93 Å²	93	141.1 Å²	141.1	77%	0.769	81%	0.812	S	S	*	*			trans	-78.6	123.6	-168.4	0	0	0	0	0	113.1	V45	A43-V45 PolarHBondContact O-N 3.06Å; A43-V45 VanDerWaalsContact O-N 3.11Å
44	I	29.2	Very low	31.4	Very low	150 Å²	150	139.4 Å²	139.4	77%	0.769	81%	0.806	S	S	*	*			trans	-81.7	90.6	173.4	-56.1	179.1	0	0	0	109.5	Q46	I44-Q46 HydrophobicContact CG2-CG 4.07Å; I44-Q46 PolarHBondContact O-N 3.11Å
45	V	28.8	Very low	31.5	Very low	122 Å²	122	142.7 Å²	142.7	74%	0.739	81%	0.811	S	S	*	*			trans	-70	98.2	165.8	179.2	0	0	0	0	108.5	A43 Q47	A43-V45 PolarHBondContact O-N 3.06Å; A43-V45 VanDerWaalsContact O-N 3.11Å; V45-Q47 PolarHBondContact O-N 2.95Å
46	Q	30.6	Very low	32.2	Very low	176 Å²	176	142.7 Å²	142.7	82%	0.822	80%	0.803	S	S	*	*			trans	-69.9	94	174.7	-68.4	-171.2	0.3	0	0	110.4	I44 A48	I44-Q46 HydrophobicContact CG2-CG 4.07Å; I44-Q46 PolarHBondContact O-N 3.11Å; Q46-A48 PolarHBondContact O-N 3.21Å
47	Q	28.5	Very low	32.9	Very low	183 Å²	183	142.2 Å²	142.2	86%	0.855	80%	0.8	S	S	*	*			trans	-64.3	115.7	166.6	-72.9	-173.5	-10.3	0	0	109.4	V45 A49	V45-Q47 PolarHBondContact O-N 2.95Å; Q47-A49 PolarHBondContact O-N 3.19Å
48	A	29.1	Very low	33.6	Very low	100 Å²	100	142.8 Å²	142.8	83%	0.826	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-62.1	119.7	174.4	0	0	0	0	0	109.9	Q46 A50	Q46-A48 PolarHBondContact O-N 3.21Å; A48-A50 PolarHBondContact O-N 3.32Å
49	A	30.9	Very low	35.3	Very low	102 Å²	102	140.9 Å²	140.9	84%	0.843	79%	0.793	S	S	*	*	P	Polyproline II helix	trans	-61.8	127.9	178	0	0	0	0	0	110.5	Q47	Q47-A49 PolarHBondContact O-N 3.19Å
50	A	31.5	Very low	37.6	Very low	82 Å²	82	136.9 Å²	136.9	68%	0.678	77%	0.774	S	S	*	*	P	Polyproline II helix	trans	-58.1	149.6	176.7	0	0	0	0	0	111.4	A48 S52	A48-A50 PolarHBondContact O-N 3.32Å; A50-S52 PolarHBondContact O-N 3.4Å
51	P	36.5	Very low	40.1	Very low	121 Å²	121	130.3 Å²	130.3	79%	0.786	75%	0.746	S	S	*	*	P	Polyproline II helix	trans	-55.7	136.1	179.2	23.4	-34.4	0	0	0	111	R53	P51-R53 PolarHBondContact O-N 3.02Å
52	S	36.8	Very low	42.7	Very low	117 Å²	117	124.5 Å²	124.5	82%	0.818	71%	0.707	S	S	*	*			trans	-50.3	103	-170.7	-60.5	0	0	0	0	112.5	A50 M54	A50-S52 PolarHBondContact O-N 3.4Å; S52-M54 PolarHBondContact O-N 2.94Å; S52-M54 VanDerWaalsContact O-N 3.09Å
53	R	41.4	Very low	45.4	Very low	221 Å²	221	120.3 Å²	120.3	83%	0.834	69%	0.69	S	S	*	*			trans	-61.9	112.9	167.8	-74.8	177.6	169.5	176.1	-1.8	107.8	P51 Q55	P51-R53 PolarHBondContact O-N 3.02Å; R53-Q55 PolarHBondContact O-N 3.27Å
54	M	41.8	Very low	48	Very low	137 Å²	137	117.6 Å²	117.6	68%	0.675	66%	0.662	S	S	*	*	P	Polyproline II helix	trans	-52.6	116.5	170.8	-64.2	-179.1	76.1	0	0	109.2	S52 L164	S52-M54 PolarHBondContact O-N 2.94Å; S52-M54 VanDerWaalsContact O-N 3.09Å; M54-L164 HydrophobicContact CE-CD2 3.55Å
55	Q	36.4	Very low	50.7	Low	187 Å²	187	115.6 Å²	115.6	87%	0.874	66%	0.662	S	S	*	*	P	Polyproline II helix	trans	-73.4	137.8	172.4	-76.2	-178.4	-28.2	0	0	109.1	R53	R53-Q55 PolarHBondContact O-N 3.27Å
56	M	45.1	Very low	53.7	Low	132 Å²	132	112.2 Å²	112.2	65%	0.65	64%	0.638	S	S	*	*	P	Polyproline II helix	trans	-74.5	128.6	-177.2	-66.6	-77.8	-68.2	0	0	110.2	L202	M56-L202 HydrophobicContact CE-CD1 4.38Å
57	P	44.8	Very low	56.8	Low	116 Å²	116	107.2 Å²	107.2	75%	0.753	62%	0.619	S	S	*	*	P	Polyproline II helix	trans	-60.1	142	161.1	-19.7	32.7	0	0	0	110.2	G59	P57-G59 PolarHBondContact O-N 2.96Å
58	Q	43.4	Very low	60	Low	207 Å²	207	99.2 Å²	99.2	97%	0.967	58%	0.583	S	S	*	*	S	Bend	trans	-79.7	102.8	170.2	-68.2	-178.3	-6.8	0	0	109
59	G	61.8	Low	63.2	Low	62 Å²	62	102 Å²	102	64%	0.639	58%	0.579	S	S	*	*	S	Bend	trans	171.4	-174.8	-179	0	0	0	0	0	113	P57 P61	P57-G59 PolarHBondContact O-N 2.96Å; G59-P61 WeakPolarHBondContact O-CD 3.22Å
60	N	77.3	Confident	66.3	Low	82 Å²	82	101.1 Å²	101.1	44%	0.439	56%	0.557	S	S	.	*			trans	-67.6	118.5	170	176.8	-2.9	0	0	0	109	L62 L63	N60-L62 PolarHBondContact O-N 3.26Å; N60-L62 VanDerWaalsContact O-N 3.14Å; N60-L62 VanDerWaalsContact OD1-CB 3.27Å; N60-L62 WeakPolarHBondContact OD1-CB 3.39Å; N60-L62 PolarHBondContact OD1-N 3.19Å; N60-L62 VanDerWaalsContact OD1-N 3.08Å; N60-L63 HydrophobicContact CB-CD1 4.08Å; N60-L63 HydrophobicContact CB-CG 4.15Å; N60-L63 PolarHBondContact O-N 2.9Å
61	P	82.4	Confident	69.5	Low	34 Å²	34	97.2 Å²	97.2	22%	0.221	53%	0.525	C	S	.	.	T	Hydrogen-bonded Turn	trans	-65.8	-18.9	-174.4	28.6	-37.1	0	0	0	113.8	G59 L63 L202 F209 Y395 Q399	G59-P61 WeakPolarHBondContact O-CD 3.22Å; P61-L63 PolarHBondContact O-N 2.67Å; P61-L202 HydrophobicContact CB-CD1 3.56Å; P61-L202 HydrophobicContact CG-CD1 4.13Å; P61-F209 HydrophobicContact CG-CD1 3.62Å; P61-F209 HydrophobicContact CG-CD2 4.49Å; P61-F209 HydrophobicContact CG-CE1 3.63Å; P61-F209 HydrophobicContact CG-CG 4.08Å; P61-F209 HydrophobicContact CG-CZ 4.1Å; P61-Y395 PolarHBondContact O-OH 3.05Å; P61-Q399 PolarHBondContact O-NE2 2.94Å
62	L	84.6	Confident	72.3	Confident	11 Å²	11	93.7 Å²	93.7	6%	0.058	50%	0.499	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63.7	-26.6	172.9	-167.8	80.2	0	0	0	112.6	N60 L210 Y395 H398 Q402	N60-L62 PolarHBondContact O-N 3.26Å; N60-L62 VanDerWaalsContact O-N 3.14Å; N60-L62 VanDerWaalsContact OD1-CB 3.27Å; N60-L62 WeakPolarHBondContact OD1-CB 3.39Å; N60-L62 PolarHBondContact OD1-N 3.19Å; N60-L62 VanDerWaalsContact OD1-N 3.08Å; L62-L210 HydrophobicContact CD1-CD2 3.83Å; L62-Y395 HydrophobicContact CD1-CD2 3.78Å; L62-Y395 HydrophobicContact CD1-CE2 4.2Å; L62-H398 HydrophobicContact CD1-CB 4.46Å; L62-Q402 PolarHBondContact O-NE2 3.38Å
63	L	85.3	Confident	75.2	Confident	92 Å²	92	91.9 Å²	91.9	48%	0.482	49%	0.491	S	S	.	.			trans	-92	137.7	-171.7	-60.3	-179.7	0	0	0	112.8	N60 P61 Q402	N60-L63 HydrophobicContact CB-CD1 4.08Å; N60-L63 HydrophobicContact CB-CG 4.15Å; N60-L63 PolarHBondContact O-N 2.9Å; P61-L63 PolarHBondContact O-N 2.67Å; L63-Q402 VanDerWaalsContact CA-OE1 3.3Å
64	L	82.6	Confident	77.8	Confident	35 Å²	35	83.8 Å²	83.8	18%	0.183	46%	0.461	C	S	.	.			trans	-104.1	93.7	169.1	-73.3	-171.8	0	0	0	111	H66 Q399 L403	L64-H66 PolarHBondContact O-N 2.69Å; L64-Q399 HydrophobicContact CD1-CB 3.95Å; L64-Q399 WeakPolarHBondContact CD1-O 3.43Å; L64-Q399 HydrophobicContact CG-CB 4.03Å; L64-Q399 HydrophobicContact CG-CG 4.24Å; L64-L403 HydrophobicContact CD1-CB 4.35Å
65	S	84.9	Confident	80.5	Confident	108 Å²	108	77.5 Å²	77.5	76%	0.755	43%	0.43	S	S	*	.			trans	-76.1	83.8	173	-58.7	0	0	0	0	111.4
66	H	92.1	Very high	83.4	Confident	51 Å²	51	70.6 Å²	70.6	24%	0.236	40%	0.4	C	S	.	.			trans	-136.2	143.1	171.8	-75	-43.6	0	0	0	112.8	L64 E70 L71 R74 V406	L64-H66 PolarHBondContact O-N 2.69Å; H66-E70 WeakPolarHBondContact CA-OE2 3.48Å; H66-E70 IonicContact CE1-OE2 3.72Å; H66-E70 IonicContact CG-OE2 2.88Å; H66-E70 IonicContact ND1-OE2 3.89Å; H66-E70 PolarHBondContact ND1-OE2 2.95Å; H66-L71 HydrophobicContact CB-CD2 3.96Å; H66-L71 HydrophobicContact CB-CG 4.18Å; H66-R74 PolarHBondContact CE1-NH2 3.19Å; H66-R74 PolarHBondContact NE2-NH2 3.49Å; H66-V406 VanDerWaalsContact O-CG1 3.28Å; H66-V406 WeakPolarHBondContact O-CG1 3.47Å; H66-V406 VanDerWaalsContact O-CG2 3.24Å; H66-V406 WeakPolarHBondContact O-CG2 3.39Å
67	T	95.4	Very high	85.9	Confident	71 Å²	71	64.3 Å²	64.3	44%	0.436	37%	0.369	S	S	.	.			trans	-93.2	157.8	165.6	65.6	0	0	0	0	112.1	Q69 E70 L71	T67-Q69 PolarHBondContact O-N 3.22Å; T67-E70 VanDerWaalsContact CB-OE1 3.26Å; T67-E70 WeakPolarHBondContact CB-OE1 3.24Å; T67-E70 VanDerWaalsContact CG2-OE1 3.26Å; T67-E70 WeakPolarHBondContact CG2-OE1 3.44Å; T67-E70 PolarHBondContact N-OE1 3.44Å; T67-E70 PolarHBondContact N-OE2 3.26Å; T67-E70 PolarHBondContact O-N 2.8Å; T67-E70 VanDerWaalsContact OG1-CD 3.3Å; T67-E70 WeakPolarHBondContact OG1-CG 3.32Å; T67-E70 PolarHBondContact OG1-N 2.99Å; T67-E70 PolarHBondContact OG1-OE1 2.98Å; T67-L71 PolarHBondContact O-N 2.88Å
68	L	96.1	Very high	88.5	Confident	16 Å²	16	62.6 Å²	62.6	8%	0.084	35%	0.351	C	S	.	.	H	α-helix	trans	-56.8	-34.2	173.6	-177.5	55.1	0	0	0	112.1	L71 L72 V406 Y407 P409 L410	L68-L71 PolarHBondContact O-N 3.28Å; L68-L72 HydrophobicContact CD1-CD1 3.98Å; L68-L72 HydrophobicContact CD1-CG 3.98Å; L68-L72 HydrophobicContact CG-CD1 3.85Å; L68-L72 HydrophobicContact CG-CG 4.29Å; L68-L72 WeakPolarHBondContact O-CB 3.18Å; L68-L72 VanDerWaalsContact O-CG 3.25Å; L68-L72 WeakPolarHBondContact O-CG 3.18Å; L68-L72 PolarHBondContact O-N 3.42Å; L68-V406 WeakPolarHBondContact CB-O 3.38Å; L68-Y407 HydrophobicContact CD1-CD1 3.58Å; L68-Y407 HydrophobicContact CD1-CE1 3.81Å; L68-Y407 HydrophobicContact CD1-CG 4.22Å; L68-P409 HydrophobicContact CD2-CB 3.93Å; L68-L410 HydrophobicContact CD2-CB 4.27Å
69	Q	96.6	Very high	91.1	Very high	159 Å²	159	52.7 Å²	52.7	74%	0.743	31%	0.305	S	S	*	.	H	α-helix	trans	-67.5	-43.5	179.7	-176.6	171.5	-18.1	0	0	111.9	T67 L72 A73	T67-Q69 PolarHBondContact O-N 3.22Å; Q69-L72 PolarHBondContact O-N 3.36Å; Q69-A73 VanDerWaalsContact O-CB 3.24Å; Q69-A73 WeakPolarHBondContact O-CB 3.4Å; Q69-A73 PolarHBondContact O-N 3.37Å
70	E	96.6	Very high	92.7	Very high	83 Å²	83	53.3 Å²	53.3	39%	0.388	29%	0.291	S	S	.	.	H	α-helix	trans	-58.8	-48.3	173.4	-71.2	152	-118.4	0	0	111.6	H66 T67 L72 A73 R74	H66-E70 WeakPolarHBondContact CA-OE2 3.48Å; H66-E70 IonicContact CE1-OE2 3.72Å; H66-E70 IonicContact CG-OE2 2.88Å; H66-E70 IonicContact ND1-OE2 3.89Å; H66-E70 PolarHBondContact ND1-OE2 2.95Å; T67-E70 VanDerWaalsContact CB-OE1 3.26Å; T67-E70 WeakPolarHBondContact CB-OE1 3.24Å; T67-E70 VanDerWaalsContact CG2-OE1 3.26Å; T67-E70 WeakPolarHBondContact CG2-OE1 3.44Å; T67-E70 PolarHBondContact N-OE1 3.44Å; T67-E70 PolarHBondContact N-OE2 3.26Å; T67-E70 PolarHBondContact O-N 2.8Å; T67-E70 VanDerWaalsContact OG1-CD 3.3Å; T67-E70 WeakPolarHBondContact OG1-CG 3.32Å; T67-E70 PolarHBondContact OG1-N 2.99Å; T67-E70 PolarHBondContact OG1-OE1 2.98Å; E70-L72 PolarHBondContact O-N 3.26Å; E70-A73 PolarHBondContact O-N 3.33Å; E70-A73 VanDerWaalsContact O-N 3.15Å; E70-R74 PolarHBondContact O-N 3.44Å; E70-R74 VanDerWaalsContact O-N 3.12Å
71	L	96.9	Very high	93.4	Very high	0 Å²	0	52.9 Å²	52.9	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-63.2	-44.3	-178.1	-61.3	-176.6	0	0	0	111.5	H66 T67 L68 A73 R74 R161 P163 L403 V406 Y407	H66-L71 HydrophobicContact CB-CD2 3.96Å; H66-L71 HydrophobicContact CB-CG 4.18Å; T67-L71 PolarHBondContact O-N 2.88Å; L68-L71 PolarHBondContact O-N 3.28Å; L71-A73 PolarHBondContact O-N 2.93Å; L71-R74 PolarHBondContact O-N 2.99Å; L71-R161 VanDerWaalsContact O-CB 3.29Å; L71-R161 WeakPolarHBondContact O-CB 3.37Å; L71-R161 WeakPolarHBondContact O-CD 3.11Å; L71-R161 WeakPolarHBondContact O-CG 3.43Å; L71-P163 HydrophobicContact CD2-CG 4Å; L71-L403 HydrophobicContact CD1-CD1 3.41Å; L71-L403 VanDerWaalsContact CD1-CD1 3.41Å; L71-V406 HydrophobicContact CD1-CB 4.29Å; L71-V406 HydrophobicContact CD1-CG1 3.56Å; L71-V406 HydrophobicContact CG-CG1 4.35Å; L71-Y407 HydrophobicContact CD1-CD2 4.23Å; L71-Y407 HydrophobicContact CD1-CE2 3.65Å
72	L	96.4	Very high	93.7	Very high	46 Å²	46	53.1 Å²	53.1	24%	0.241	29%	0.287	C	S	.	.	H	α-helix	trans	-64.9	-28.7	175.7	-69.1	175.2	0	0	0	112.9	L68 Q69 E70 R161	L68-L72 HydrophobicContact CD1-CD1 3.98Å; L68-L72 HydrophobicContact CD1-CG 3.98Å; L68-L72 HydrophobicContact CG-CD1 3.85Å; L68-L72 HydrophobicContact CG-CG 4.29Å; L68-L72 WeakPolarHBondContact O-CB 3.18Å; L68-L72 VanDerWaalsContact O-CG 3.25Å; L68-L72 WeakPolarHBondContact O-CG 3.18Å; L68-L72 PolarHBondContact O-N 3.42Å; Q69-L72 PolarHBondContact O-N 3.36Å; E70-L72 PolarHBondContact O-N 3.26Å; L72-R161 PolarHBondContact O-NE 3.48Å
73	A	96.7	Very high	93.4	Very high	79 Å²	79	57.2 Å²	57.2	65%	0.653	32%	0.315	S	S	*	.	H	α-helix	trans	-82	-14	178.5	0	0	0	0	0	114.7	Q69 E70 L71 D75	Q69-A73 VanDerWaalsContact O-CB 3.24Å; Q69-A73 WeakPolarHBondContact O-CB 3.4Å; Q69-A73 PolarHBondContact O-N 3.37Å; E70-A73 PolarHBondContact O-N 3.33Å; E70-A73 VanDerWaalsContact O-N 3.15Å; L71-A73 PolarHBondContact O-N 2.93Å; A73-D75 PolarHBondContact O-N 2.66Å
74	R	96.5	Very high	92.6	Very high	52 Å²	52	59.5 Å²	59.5	20%	0.196	32%	0.323	C	S	.	.	S	Bend	trans	-58	-43.9	-179.1	-78.3	-178	179.2	-119.6	5	113	H66 E70 L71 R101 P163 S166 E167	H66-R74 PolarHBondContact CE1-NH2 3.19Å; H66-R74 PolarHBondContact NE2-NH2 3.49Å; E70-R74 PolarHBondContact O-N 3.44Å; E70-R74 VanDerWaalsContact O-N 3.12Å; L71-R74 PolarHBondContact O-N 2.99Å; R74-R101 WeakPolarHBondContact O-CD 3.2Å; R74-P163 PolarHBondContact NH1-O 3.48Å; R74-P163 VanDerWaalsContact NH1-O 3.13Å; R74-S166 PolarHBondContact NH1-OG 3.09Å; R74-E167 IonicContact NH1-OE1 3.51Å
75	D	97.9	Very high	91.7	Very high	5 Å²	5	65.2 Å²	65.2	3%	0.027	35%	0.347	C	S	.	.			trans	-158.8	161.3	168.7	-161.2	2	0	0	0	110.1	A73 V77 S99 Q100 R101 A160 R161	A73-D75 PolarHBondContact O-N 2.66Å; D75-V77 HydrophobicContact CB-CG2 4.49Å; D75-V77 WeakPolarHBondContact OD2-CG2 3.36Å; D75-S99 VanDerWaalsContact CG-OG 3.31Å; D75-S99 PolarHBondContact OD1-OG 3.09Å; D75-S99 WeakPolarHBondContact OD2-CB 3.27Å; D75-S99 PolarHBondContact OD2-OG 3.39Å; D75-Q100 PolarHBondContact OD1-N 3.15Å; D75-Q100 VanDerWaalsContact OD1-N 3.07Å; D75-R101 HydrophobicContact CB-CB 3.91Å; D75-R101 VanDerWaalsContact CG-CB 3.43Å; D75-R101 WeakPolarHBondContact OD1-CB 3.28Å; D75-R101 PolarHBondContact OD1-N 3.43Å; D75-A160 HydrophobicContact CB-CB 4Å; D75-R161 VanDerWaalsContact O-CZ 3.31Å; D75-R161 PolarHBondContact O-NE 3.28Å; D75-R161 PolarHBondContact O-NH2 3.05Å
76	T	97.9	Very high	90	Very high	42 Å²	42	70.4 Å²	70.4	26%	0.258	36%	0.355	S	S	.	.			trans	-129.9	114.5	162.3	-65.5	0	0	0	0	108	Q100 R161	T76-Q100 WeakPolarHBondContact O-CB 3.44Å; T76-Q100 PolarHBondContact O-N 2.91Å; T76-R161 PolarHBondContact OG1-NH2 3.41Å
77	V	98.4	Very high	88.4	Confident	0 Å²	0	71.4 Å²	71.4	0%	0	38%	0.38	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-104.6	126.2	-177.2	-175.9	0	0	0	0	109.7	D75 V79 V97 S98 V156 N157 A160 L175	D75-V77 HydrophobicContact CB-CG2 4.49Å; D75-V77 WeakPolarHBondContact OD2-CG2 3.36Å; V77-V79 HydrophobicContact CG1-CG2 4.42Å; V77-V97 HydrophobicContact CG1-CG1 3.73Å; V77-S98 CarbonylContact C-O 3.56Å; V77-S98 WeakPolarHBondContact CA-O 3.4Å; V77-V156 HydrophobicContact CB-CG1 3.9Å; V77-V156 HydrophobicContact CG1-CG1 3.57Å; V77-V156 HydrophobicContact CG1-CG2 4.15Å; V77-N157 PolarHBondContact N-OD1 3.36Å; V77-N157 PolarHBondContact O-ND2 3.46Å; V77-A160 HydrophobicContact CG2-CB 4Å; V77-L175 HydrophobicContact CG1-CD2 4.01Å; V77-L175 HydrophobicContact CG2-CD1 4.09Å; V77-L175 HydrophobicContact CG2-CD2 4.37Å
78	Q	98.3	Very high	86.6	Confident	79 Å²	79	73.2 Å²	73.2	37%	0.369	39%	0.386	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.4	147.6	169	-51.4	-58.4	-22.3	0	0	109.6	V97 S98	Q78-V97 WeakPolarHBondContact O-CA 3.37Å; Q78-S98 PolarHBondContact N-O 3.1Å; Q78-S98 PolarHBondContact O-N 3.22Å
79	V	98	Very high	84.8	Confident	0 Å²	0	82.1 Å²	82.1	0%	0	42%	0.424	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.7	100.8	175	-179.8	0	0	0	0	106.9	V77 Y95 E96 V97 F113 R149 L152 K153 V156	V77-V79 HydrophobicContact CG1-CG2 4.42Å; V79-Y95 HydrophobicContact CG1-CD1 4.37Å; V79-Y95 HydrophobicContact CG1-CG 4.28Å; V79-E96 CarbonylContact C-O 3.58Å; V79-E96 VanDerWaalsContact CA-O 3.29Å; V79-E96 WeakPolarHBondContact CA-O 3.44Å; V79-V97 HydrophobicContact CG1-CG2 4.46Å; V79-V97 HydrophobicContact CG2-CG1 4.35Å; V79-V97 HydrophobicContact CG2-CG2 4.39Å; V79-F113 HydrophobicContact CG1-CZ 4.41Å; V79-R149 HydrophobicContact CG1-CG 4.26Å; V79-R149 WeakPolarHBondContact O-CD 3.39Å; V79-R149 WeakPolarHBondContact O-CG 3.26Å; V79-R149 PolarHBondContact O-NH1 2.8Å; V79-L152 HydrophobicContact CG1-CB 4.25Å; V79-K153 HydrophobicContact CB-CB 3.95Å; V79-K153 HydrophobicContact CB-CG 4.2Å; V79-K153 HydrophobicContact CG2-CB 4.14Å; V79-K153 HydrophobicContact CG2-CG 4.31Å; V79-V156 HydrophobicContact CG2-CG1 3.65Å
80	E	96.5	Very high	83.1	Confident	75 Å²	75	77.1 Å²	77.1	35%	0.35	40%	0.402	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-113.8	151	-175.1	-56.7	-49.2	137.5	0	0	111.3	Y95 E96 R149 K153	E80-Y95 CarbonylContact O-C 3.55Å; E80-Y95 VanDerWaalsContact O-CA 3.25Å; E80-Y95 WeakPolarHBondContact O-CA 3.41Å; E80-E96 PolarHBondContact N-O 3.29Å; E80-E96 PolarHBondContact O-N 2.87Å; E80-R149 IonicContact OE1-NH1 3.65Å; E80-R149 PolarHBondContact OE1-NH1 3.28Å; E80-R149 IonicContact OE2-CZ 2.82Å; E80-R149 IonicContact OE2-NE 3.9Å; E80-R149 IonicContact OE2-NH1 2.71Å; E80-R149 PolarHBondContact OE2-NH1 2.68Å; E80-K153 IonicContact OE1-NZ 3.7Å; E80-K153 PolarHBondContact OE1-NZ 2.85Å
81	L	92.3	Very high	81.8	Confident	73 Å²	73	82.4 Å²	82.4	38%	0.382	42%	0.424	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-81.2	124.1	-177.2	176.5	65.7	0	0	0	109.8	P83 V93 Y95 I145	L81-P83 WeakPolarHBondContact O-CD 3.18Å; L81-V93 HydrophobicContact CD1-CG1 3.44Å; L81-V93 VanDerWaalsContact CD1-CG1 3.44Å; L81-Y95 HydrophobicContact CD1-CD1 4.37Å; L81-Y95 HydrophobicContact CD1-CE1 4.1Å; L81-I145 HydrophobicContact CD1-CG2 3.67Å; L81-I145 HydrophobicContact CD2-CG2 3.75Å; L81-I145 HydrophobicContact CG-CG2 4.35Å
82	I	88.6	Confident	80.8	Confident	38 Å²	38	86.7 Å²	86.7	20%	0.195	44%	0.444	C	S	.	.	P	Polyproline II helix	trans	-75.1	122.7	171.8	-70.1	-56.9	0	0	0	109.5	E94 E96 Y107	I82-E94 PolarHBondContact N-O 2.93Å; I82-E96 HydrophobicContact CD1-CB 3.92Å; I82-E96 HydrophobicContact CG1-CB 4.26Å; I82-Y107 HydrophobicContact CD1-CD1 4.45Å; I82-Y107 HydrophobicContact CD1-CE1 3.94Å; I82-Y107 HydrophobicContact CG1-CD1 4.08Å; I82-Y107 HydrophobicContact CG1-CE1 4.06Å
83	P	77.6	Confident	80.3	Confident	98 Å²	98	86.6 Å²	86.6	64%	0.636	45%	0.445	S	S	*	.	P	Polyproline II helix	trans	-71.7	138.3	176.5	29.6	-34	0	0	0	110.5	L81 K85	L81-P83 WeakPolarHBondContact O-CD 3.18Å; P83-K85 PolarHBondContact O-N 2.8Å; P83-K85 VanDerWaalsContact O-N 3.11Å
84	E	69.1	Low	80	Confident	140 Å²	140	86 Å²	86	65%	0.654	43%	0.429	S	S	*	.			trans	-60.4	114.9	174.2	-67.1	-179.2	-176.9	0	0	110.1	K86 L90	E84-K86 PolarHBondContact O-N 2.84Å; E84-L90 HydrophobicContact CG-CD1 4.35Å
85	K	62.4	Low	80	Confident	155 Å²	155	83.5 Å²	83.5	67%	0.674	42%	0.419	S	S	*	.			trans	-69.1	126.1	176.3	-70	179.9	179.8	177.2	0	108.7	P83 G87 L88	P83-K85 PolarHBondContact O-N 2.8Å; P83-K85 VanDerWaalsContact O-N 3.11Å; K85-G87 PolarHBondContact O-N 3.39Å; K85-G87 VanDerWaalsContact O-N 3.08Å; K85-L88 HydrophobicContact CB-CB 4.49Å; K85-L88 PolarHBondContact O-N 3.29Å
86	K	50.1	Low	79.9	Confident	217 Å²	217	86.3 Å²	86.3	94%	0.943	43%	0.432	S	S	*	.	T	Hydrogen-bonded Turn	trans	-48.4	118	176.5	-69.2	-174.9	177.6	-177.6	0	110.3	E84	E84-K86 PolarHBondContact O-N 2.84Å
87	G	57.4	Low	80	Confident	72 Å²	72	84.3 Å²	84.3	74%	0.742	42%	0.42	S	S	*	.	T	Hydrogen-bonded Turn	trans	99.7	-13.7	-178.3	0	0	0	0	0	115.9	K85	K85-G87 PolarHBondContact O-N 3.39Å; K85-G87 VanDerWaalsContact O-N 3.08Å
88	L	59.3	Low	80	Confident	108 Å²	108	85.8 Å²	85.8	57%	0.565	43%	0.43	S	S	*	.			trans	-104	107.5	172.9	-93.9	70.5	0	0	0	110.9	K85 L90	K85-L88 HydrophobicContact CB-CB 4.49Å; K85-L88 PolarHBondContact O-N 3.29Å; L88-L90 PolarHBondContact O-N 3.06Å
89	F	57.3	Low	80	Confident	204 Å²	204	82.3 Å²	82.3	90%	0.895	41%	0.414	S	S	*	.			trans	-74.6	91.4	170.8	-67.4	-80.6	0	0	0	110.8	K91	F89-K91 PolarHBondContact O-N 3.17Å
90	L	61.1	Low	80	Confident	53 Å²	53	88.9 Å²	88.9	28%	0.277	45%	0.445	S	S	.	.			trans	-67.8	117.9	171.2	-65	-179.6	0	0	0	109.7	E84 L88 H92	E84-L90 HydrophobicContact CG-CD1 4.35Å; L88-L90 PolarHBondContact O-N 3.06Å; L90-H92 PolarHBondContact O-N 3.38Å; L90-H92 VanDerWaalsContact O-N 3.16Å
91	K	68.6	Low	80	Confident	195 Å²	195	89.9 Å²	89.9	85%	0.848	45%	0.446	S	S	*	.	S	Bend	trans	-65.5	-15.5	178.6	-72.3	-176	176.6	178.5	0	113.7	F89	F89-K91 PolarHBondContact O-N 3.17Å
92	H	76.6	Confident	80.2	Confident	90 Å²	90	88.9 Å²	88.9	42%	0.417	44%	0.439	S	S	.	.	S	Bend	trans	-146.3	153.1	-177.8	-51.7	97.9	0	0	0	109.7	L90 E94 R109	L90-H92 PolarHBondContact O-N 3.38Å; L90-H92 VanDerWaalsContact O-N 3.16Å; H92-E94 PolarHBondContact O-N 3Å; H92-R109 HydrophobicContact CB-CB 4.48Å
93	V	86.5	Confident	80.6	Confident	43 Å²	43	96.5 Å²	96.5	26%	0.261	47%	0.47	S	S	.	.			trans	-68.9	126.6	167.3	-179.8	0	0	0	0	109.5	L81 Y95 I145	L81-V93 HydrophobicContact CD1-CG1 3.44Å; L81-V93 VanDerWaalsContact CD1-CG1 3.44Å; V93-Y95 HydrophobicContact CG1-CE1 3.96Å; V93-Y95 HydrophobicContact CG1-CE2 4.25Å; V93-I145 HydrophobicContact CG1-CG2 4.16Å; V93-I145 HydrophobicContact CG2-CD1 4.24Å
94	E	90.6	Very high	81.6	Confident	67 Å²	67	93 Å²	93	31%	0.313	45%	0.448	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.8	147.8	177.1	-65.4	-174.9	155.5	0	0	110.9	I82 H92 R109	I82-E94 PolarHBondContact N-O 2.93Å; H92-E94 PolarHBondContact O-N 3Å; E94-R109 HydrophobicContact CG-CB 4.39Å
95	Y	95.1	Very high	82.9	Confident	0 Å²	0	88.9 Å²	88.9	0%	0	44%	0.435	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.5	138.9	-178.9	-53.7	-78.4	0	0	0	109.2	V79 E80 L81 V93 Y107 R108 F113 R148 R149 L152	V79-Y95 HydrophobicContact CG1-CD1 4.37Å; V79-Y95 HydrophobicContact CG1-CG 4.28Å; E80-Y95 CarbonylContact O-C 3.55Å; E80-Y95 VanDerWaalsContact O-CA 3.25Å; E80-Y95 WeakPolarHBondContact O-CA 3.41Å; L81-Y95 HydrophobicContact CD1-CD1 4.37Å; L81-Y95 HydrophobicContact CD1-CE1 4.1Å; V93-Y95 HydrophobicContact CG1-CE1 3.96Å; V93-Y95 HydrophobicContact CG1-CE2 4.25Å; Y95-Y107 WeakPolarHBondContact O-CA 3.04Å; Y95-R108 WeakPolarHBondContact CD2-O 3.36Å; Y95-R108 PolarHBondContact N-O 3.36Å; Y95-R108 PolarHBondContact O-N 3.3Å; Y95-F113 HydrophobicContact CD2-CE2 4.32Å; Y95-R148 WeakPolarHBondContact OH-CD 3.3Å; Y95-R149 HydrophobicContact CD1-CB 4.38Å; Y95-R149 HydrophobicContact CD1-CG 4.15Å; Y95-R149 HydrophobicContact CE1-CB 4.01Å; Y95-R149 HydrophobicContact CE1-CG 4.28Å; Y95-L152 HydrophobicContact CD2-CD1 3.84Å; Y95-L152 HydrophobicContact CE1-CD1 4.46Å; Y95-L152 HydrophobicContact CE2-CD1 3.54Å; Y95-L152 HydrophobicContact CG-CD1 4.43Å
96	E	97.2	Very high	84.6	Confident	64 Å²	64	81.7 Å²	81.7	30%	0.299	40%	0.404	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.8	122.5	164.2	-164.9	-176	158.4	0	0	108.5	V79 E80 I82 S98 S105 Y107	V79-E96 CarbonylContact C-O 3.58Å; V79-E96 VanDerWaalsContact CA-O 3.29Å; V79-E96 WeakPolarHBondContact CA-O 3.44Å; E80-E96 PolarHBondContact N-O 3.29Å; E80-E96 PolarHBondContact O-N 2.87Å; I82-E96 HydrophobicContact CD1-CB 3.92Å; I82-E96 HydrophobicContact CG1-CB 4.26Å; E96-S98 PolarHBondContact OE1-OG 3.15Å; E96-S105 VanDerWaalsContact CD-OG 3.24Å; E96-S105 WeakPolarHBondContact CG-OG 3.39Å; E96-S105 WeakPolarHBondContact OE1-CB 3.3Å; E96-S105 PolarHBondContact OE1-OG 3.07Å; E96-Y107 HydrophobicContact CB-CE1 4.45Å; E96-Y107 HydrophobicContact CG-CE1 4.23Å
97	V	98.4	Very high	86.8	Confident	0 Å²	0	78.3 Å²	78.3	0%	0	39%	0.386	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.1	111.8	179.6	-175.8	0	0	0	0	108.6	V77 Q78 V79 V106 R108 F113 L175	V77-V97 HydrophobicContact CG1-CG1 3.73Å; Q78-V97 WeakPolarHBondContact O-CA 3.37Å; V79-V97 HydrophobicContact CG1-CG2 4.46Å; V79-V97 HydrophobicContact CG2-CG1 4.35Å; V79-V97 HydrophobicContact CG2-CG2 4.39Å; V97-V106 HydrophobicContact CB-CG2 4.23Å; V97-V106 PolarHBondContact N-O 3.43Å; V97-V106 PolarHBondContact O-N 2.89Å; V97-R108 HydrophobicContact CB-CG 4.29Å; V97-R108 HydrophobicContact CG2-CB 3.88Å; V97-R108 HydrophobicContact CG2-CG 3.76Å; V97-F113 HydrophobicContact CG2-CE2 4.23Å; V97-F113 HydrophobicContact CG2-CZ 3.71Å; V97-L175 HydrophobicContact CG1-CD2 3.6Å
98	S	98.5	Very high	88.6	Confident	30 Å²	30	75.2 Å²	75.2	21%	0.21	35%	0.352	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122	116.8	-169.2	-51.8	0	0	0	0	111.3	V77 Q78 E96 S104 S105	V77-S98 CarbonylContact C-O 3.56Å; V77-S98 WeakPolarHBondContact CA-O 3.4Å; Q78-S98 PolarHBondContact N-O 3.1Å; Q78-S98 PolarHBondContact O-N 3.22Å; E96-S98 PolarHBondContact OE1-OG 3.15Å; S98-S104 CarbonylContact C-O 3.27Å; S98-S104 VanDerWaalsContact CA-O 3.25Å; S98-S104 WeakPolarHBondContact CA-O 3.49Å; S98-S105 WeakPolarHBondContact OG-CB 3.27Å; S98-S105 PolarHBondContact OG-OG 3.29Å
99	S	98.4	Very high	90.3	Very high	6 Å²	6	73.6 Å²	73.6	4%	0.042	34%	0.338	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-99.4	129.1	-177.9	167.3	0	0	0	0	111.5	D75 R101 F102 K103 S104	D75-S99 VanDerWaalsContact CG-OG 3.31Å; D75-S99 PolarHBondContact OD1-OG 3.09Å; D75-S99 WeakPolarHBondContact OD2-CB 3.27Å; D75-S99 PolarHBondContact OD2-OG 3.39Å; S99-R101 PolarHBondContact OG-N 2.81Å; S99-F102 WeakPolarHBondContact OG-CD2 3.48Å; S99-F102 PolarHBondContact OG-N 3.18Å; S99-K103 WeakPolarHBondContact O-CA 3.43Å; S99-K103 PolarHBondContact O-N 2.83Å; S99-S104 PolarHBondContact N-O 3.36Å; S99-S104 PolarHBondContact O-N 2.98Å
100	Q	97.8	Very high	92	Very high	139 Å²	139	65.1 Å²	65.1	65%	0.65	30%	0.301	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71	-39.9	174.4	-170.3	176.8	12.4	0	0	111.7	D75 T76	D75-Q100 PolarHBondContact OD1-N 3.15Å; D75-Q100 VanDerWaalsContact OD1-N 3.07Å; T76-Q100 WeakPolarHBondContact O-CB 3.44Å; T76-Q100 PolarHBondContact O-N 2.91Å
101	R	97.3	Very high	93.6	Very high	96 Å²	96	65.1 Å²	65.1	36%	0.362	30%	0.301	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.5	-47.5	178.6	-178.7	-175	177	159.2	-1.8	112	R74 D75 S99 S166 E167	R74-R101 WeakPolarHBondContact O-CD 3.2Å; D75-R101 HydrophobicContact CB-CB 3.91Å; D75-R101 VanDerWaalsContact CG-CB 3.43Å; D75-R101 WeakPolarHBondContact OD1-CB 3.28Å; D75-R101 PolarHBondContact OD1-N 3.43Å; S99-R101 PolarHBondContact OG-N 2.81Å; R101-S166 PolarHBondContact NH1-O 3.05Å; R101-S166 VanDerWaalsContact NH1-O 3.11Å; R101-E167 IonicContact CZ-OE1 3.72Å; R101-E167 IonicContact CZ-OE2 2.72Å; R101-E167 IonicContact NH1-OE1 2.8Å; R101-E167 PolarHBondContact NH1-OE1 3.18Å; R101-E167 IonicContact NH1-OE2 3.46Å; R101-E167 IonicContact NH2-OE1 2.71Å; R101-E167 PolarHBondContact NH2-OE1 3.33Å; R101-E167 IonicContact NH2-OE2 3.26Å; R101-E167 PolarHBondContact NH2-OE2 3.01Å
102	F	96.8	Very high	95	Very high	52 Å²	52	56.4 Å²	56.4	23%	0.228	26%	0.264	C	S	.	.	T	Hydrogen-bonded Turn	trans	-88.9	-6.1	-176.2	-62.3	-61.8	0	0	0	113.7	S99 S104 K172 L175	S99-F102 WeakPolarHBondContact OG-CD2 3.48Å; S99-F102 PolarHBondContact OG-N 3.18Å; F102-S104 WeakPolarHBondContact CB-OG 3.43Å; F102-S104 PolarHBondContact O-N 3.39Å; F102-K172 HydrophobicContact CD1-CG 4.26Å; F102-K172 HydrophobicContact CE1-CB 4.3Å; F102-K172 HydrophobicContact CE1-CD 4.27Å; F102-K172 HydrophobicContact CE1-CG 3.87Å; F102-K172 HydrophobicContact CZ-CB 4.13Å; F102-K172 HydrophobicContact CZ-CG 4.21Å; F102-L175 HydrophobicContact CD2-CB 3.89Å; F102-L175 HydrophobicContact CD2-CD1 3.86Å; F102-L175 HydrophobicContact CE2-CB 4.4Å; F102-L175 HydrophobicContact CE2-CD1 3.9Å
103	K	97.3	Very high	96	Very high	198 Å²	198	52.1 Å²	52.1	86%	0.861	24%	0.244	S	C	*	.	T	Hydrogen-bonded Turn	trans	52.5	34.8	-177.4	-56.8	-177.1	-178.6	-179.9	0	112.7	S99	S99-K103 WeakPolarHBondContact O-CA 3.43Å; S99-K103 PolarHBondContact O-N 2.83Å
104	S	97.5	Very high	96.5	Very high	24 Å²	24	51.2 Å²	51.2	17%	0.168	24%	0.239	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-118.1	147.3	-174.6	53.8	0	0	0	0	111	S98 S99 F102 L175	S98-S104 CarbonylContact C-O 3.27Å; S98-S104 VanDerWaalsContact CA-O 3.25Å; S98-S104 WeakPolarHBondContact CA-O 3.49Å; S99-S104 PolarHBondContact N-O 3.36Å; S99-S104 PolarHBondContact O-N 2.98Å; F102-S104 WeakPolarHBondContact CB-OG 3.43Å; F102-S104 PolarHBondContact O-N 3.39Å; S104-L175 WeakPolarHBondContact CB-O 3.5Å; S104-L175 PolarHBondContact OG-O 3.01Å
105	S	97.6	Very high	96.9	Very high	54 Å²	54	48.5 Å²	48.5	38%	0.378	23%	0.227	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-121.1	131.7	161.7	170.1	0	0	0	0	107.7	E96 S98	E96-S105 VanDerWaalsContact CD-OG 3.24Å; E96-S105 WeakPolarHBondContact CG-OG 3.39Å; E96-S105 WeakPolarHBondContact OE1-CB 3.3Å; E96-S105 PolarHBondContact OE1-OG 3.07Å; S98-S105 WeakPolarHBondContact OG-CB 3.27Å; S98-S105 PolarHBondContact OG-OG 3.29Å
106	V	97.3	Very high	97	Very high	4 Å²	4	48.5 Å²	48.5	2%	0.024	23%	0.227	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-139.6	141.9	-178.7	-65.6	0	0	0	0	111.1	V97 R108 L175	V97-V106 HydrophobicContact CB-CG2 4.23Å; V97-V106 PolarHBondContact N-O 3.43Å; V97-V106 PolarHBondContact O-N 2.89Å; V106-R108 HydrophobicContact CG2-CG 4.38Å; V106-L175 WeakPolarHBondContact CG2-O 3.42Å
107	Y	95.6	Very high	97.1	Very high	146 Å²	146	47.2 Å²	47.2	57%	0.573	22%	0.22	S	C	*	.	E	Extended strand (participates in β ladder)	trans	-81.4	134.8	175.4	-55.7	-62.1	0	0	0	111.1	I82 Y95 E96	I82-Y107 HydrophobicContact CD1-CD1 4.45Å; I82-Y107 HydrophobicContact CD1-CE1 3.94Å; I82-Y107 HydrophobicContact CG1-CD1 4.08Å; I82-Y107 HydrophobicContact CG1-CE1 4.06Å; Y95-Y107 WeakPolarHBondContact O-CA 3.04Å; E96-Y107 HydrophobicContact CB-CE1 4.45Å; E96-Y107 HydrophobicContact CG-CE1 4.23Å
108	R	96.1	Very high	97	Very high	6 Å²	6	51.7 Å²	51.7	2%	0.023	24%	0.241	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-140.2	136.9	178.4	-60.7	-65.4	175.6	-114.3	6.8	110.3	Y95 V97 V106 D112 F113 L173 F174 F177	Y95-R108 WeakPolarHBondContact CD2-O 3.36Å; Y95-R108 PolarHBondContact N-O 3.36Å; Y95-R108 PolarHBondContact O-N 3.3Å; V97-R108 HydrophobicContact CB-CG 4.29Å; V97-R108 HydrophobicContact CG2-CB 3.88Å; V97-R108 HydrophobicContact CG2-CG 3.76Å; V106-R108 HydrophobicContact CG2-CG 4.38Å; R108-D112 WeakPolarHBondContact CA-OD2 3.41Å; R108-F113 HydrophobicContact CB-CD2 4.3Å; R108-F113 HydrophobicContact CB-CE2 3.71Å; R108-F113 HydrophobicContact CB-CZ 4.43Å; R108-L173 PolarHBondContact NH2-O 2.94Å; R108-F174 HydrophobicContact CB-CZ 4.4Å; R108-F174 HydrophobicContact CG-CE1 4.5Å; R108-F174 HydrophobicContact CG-CE2 4.14Å; R108-F174 HydrophobicContact CG-CZ 3.89Å; R108-F174 VanDerWaalsContact CZ-O 3.26Å; R108-F174 PolarHBondContact NE-O 3.25Å; R108-F174 PolarHBondContact NH2-O 2.99Å; R108-F177 PolarHBondContact NH1-O 3.23Å; R108-F177 VanDerWaalsContact NH1-O 3.07Å; R108-F177 PolarHBondContact NH2-O 3.06Å
109	R	94	Very high	96.9	Very high	74 Å²	74	51.4 Å²	51.4	28%	0.279	24%	0.237	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-95.8	161.5	166.9	53.1	170.9	-174.4	-168.5	-0.9	110	H92 E94 N111 D112	H92-R109 HydrophobicContact CB-CB 4.48Å; E94-R109 HydrophobicContact CG-CB 4.39Å; R109-N111 PolarHBondContact O-N 3Å; R109-N111 VanDerWaalsContact O-N 3.1Å; R109-D112 VanDerWaalsContact CG-CG 3.4Å; R109-D112 VanDerWaalsContact CG-OD1 3.26Å; R109-D112 WeakPolarHBondContact CG-OD1 3.37Å; R109-D112 WeakPolarHBondContact CG-OD2 3.43Å; R109-D112 IonicContact CZ-OD1 3.48Å; R109-D112 PolarHBondContact N-OD2 3.29Å; R109-D112 IonicContact NE-OD1 3.5Å; R109-D112 PolarHBondContact NE-OD1 3.11Å; R109-D112 IonicContact NH2-OD1 2.73Å; R109-D112 WeakPolarHBondContact O-CB 3.47Å; R109-D112 PolarHBondContact O-N 3.03Å
110	Y	94.4	Very high	96.8	Very high	26 Å²	26	51.2 Å²	51.2	10%	0.102	24%	0.235	C	C	.	.	H	α-helix	trans	-49.7	-40.3	-180	171.9	-93.2	0	0	0	114	D112 F113 V114 P133 K135 R148 L152	Y110-D112 PolarHBondContact O-N 2.99Å; Y110-F113 WeakPolarHBondContact O-CB 3.16Å; Y110-F113 PolarHBondContact O-N 2.95Å; Y110-V114 HydrophobicContact CD1-CG2 4.07Å; Y110-V114 HydrophobicContact CE1-CG2 3.41Å; Y110-V114 VanDerWaalsContact CE1-CG2 3.41Å; Y110-V114 HydrophobicContact CE2-CG2 4.43Å; Y110-V114 PolarHBondContact O-N 2.61Å; Y110-P133 HydrophobicContact CE2-CG 4.29Å; Y110-P133 VanDerWaalsContact CE2-O 3.31Å; Y110-P133 WeakPolarHBondContact CE2-O 3.29Å; Y110-P133 PolarHBondContact OH-O 2.99Å; Y110-K135 HydrophobicContact CE1-CB 4.17Å; Y110-K135 HydrophobicContact CE1-CD 4.48Å; Y110-K135 HydrophobicContact CE1-CG 3.97Å; Y110-R148 HydrophobicContact CD2-CG 4.35Å; Y110-L152 HydrophobicContact CD2-CD1 4.5Å; Y110-L152 HydrophobicContact CD2-CD2 4.28Å
111	N	94.6	Very high	96.8	Very high	54 Å²	54	47.4 Å²	47.4	29%	0.289	22%	0.219	S	C	.	.	H	α-helix	trans	-66.9	-19.2	179.8	-71.9	-15.9	0	0	0	113.7	R109 V114 V115 Q183	R109-N111 PolarHBondContact O-N 3Å; R109-N111 VanDerWaalsContact O-N 3.1Å; N111-V114 PolarHBondContact O-N 3.17Å; N111-V115 PolarHBondContact O-N 3.24Å; N111-Q183 PolarHBondContact O-NE2 3.15Å
112	D	97	Very high	96.7	Very high	11 Å²	11	47.7 Å²	47.7	6%	0.059	22%	0.224	C	C	.	.	H	α-helix	trans	-77.2	-36.4	176.8	-47	-26.2	0	0	0	110.4	R108 R109 Y110 V114 V115 F116 F174 V182 Q183	R108-D112 WeakPolarHBondContact CA-OD2 3.41Å; R109-D112 VanDerWaalsContact CG-CG 3.4Å; R109-D112 VanDerWaalsContact CG-OD1 3.26Å; R109-D112 WeakPolarHBondContact CG-OD1 3.37Å; R109-D112 WeakPolarHBondContact CG-OD2 3.43Å; R109-D112 IonicContact CZ-OD1 3.48Å; R109-D112 PolarHBondContact N-OD2 3.29Å; R109-D112 IonicContact NE-OD1 3.5Å; R109-D112 PolarHBondContact NE-OD1 3.11Å; R109-D112 IonicContact NH2-OD1 2.73Å; R109-D112 WeakPolarHBondContact O-CB 3.47Å; R109-D112 PolarHBondContact O-N 3.03Å; Y110-D112 PolarHBondContact O-N 2.99Å; D112-V114 VanDerWaalsContact C-N 3.29Å; D112-V114 PolarHBondContact O-N 3.49Å; D112-V115 PolarHBondContact O-N 3.43Å; D112-F116 WeakPolarHBondContact O-CB 3.44Å; D112-F116 PolarHBondContact O-N 3.31Å; D112-F174 HydrophobicContact CB-CE2 4.3Å; D112-V182 HydrophobicContact CB-CG1 4.14Å; D112-Q183 PolarHBondContact OD1-NE2 2.85Å
113	F	98.1	Very high	96.6	Very high	0 Å²	0	45.9 Å²	45.9	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-62.1	-37.9	169.6	-71.4	-97.7	0	0	0	111.3	V79 Y95 V97 R108 Y110 F116 Q117 L132 L152 F155 V156 F174	V79-F113 HydrophobicContact CG1-CZ 4.41Å; Y95-F113 HydrophobicContact CD2-CE2 4.32Å; V97-F113 HydrophobicContact CG2-CE2 4.23Å; V97-F113 HydrophobicContact CG2-CZ 3.71Å; R108-F113 HydrophobicContact CB-CD2 4.3Å; R108-F113 HydrophobicContact CB-CE2 3.71Å; R108-F113 HydrophobicContact CB-CZ 4.43Å; Y110-F113 WeakPolarHBondContact O-CB 3.16Å; Y110-F113 PolarHBondContact O-N 2.95Å; F113-F116 PolarHBondContact O-N 2.71Å; F113-Q117 WeakPolarHBondContact O-CB 3.47Å; F113-Q117 PolarHBondContact O-N 3.26Å; F113-L132 HydrophobicContact CB-CD1 4.27Å; F113-L132 HydrophobicContact CB-CD2 4.07Å; F113-L152 HydrophobicContact CB-CD2 4.02Å; F113-L152 HydrophobicContact CD1-CB 4.5Å; F113-L152 HydrophobicContact CD1-CD2 3.83Å; F113-L152 HydrophobicContact CD2-CD1 4.1Å; F113-L152 HydrophobicContact CD2-CD2 4.15Å; F113-L152 HydrophobicContact CE1-CB 4.08Å; F113-L152 HydrophobicContact CE1-CD2 4.25Å; F113-L152 HydrophobicContact CE2-CD1 3.97Å; F113-L152 HydrophobicContact CG-CD2 3.76Å; F113-L152 HydrophobicContact CZ-CB 4.17Å; F113-L152 HydrophobicContact CZ-CD1 4.28Å; F113-F155 HydrophobicContact CD1-CD1 4.02Å; F113-F155 HydrophobicContact CD1-CE1 4.13Å; F113-V156 HydrophobicContact CE1-CB 4.37Å; F113-F174 HydrophobicContact CD1-CE1 4.05Å; F113-F174 AromaticContact CD1-CZ 3.57Å; F113-F174 HydrophobicContact CD1-CZ 3.57Å; F113-F174 AromaticContact CD2-CZ 3.98Å; F113-F174 HydrophobicContact CD2-CZ 3.98Å; F113-F174 AromaticContact CE1-CE1 3.83Å; F113-F174 HydrophobicContact CE1-CE1 3.83Å; F113-F174 AromaticContact CE1-CZ 3.64Å; F113-F174 HydrophobicContact CE1-CZ 3.64Å; F113-F174 HydrophobicContact CE2-CZ 4.03Å; F113-F174 HydrophobicContact CG-CE2 4.43Å; F113-F174 AromaticContact CG-CZ 3.76Å; F113-F174 HydrophobicContact CG-CZ 3.76Å; F113-F174 HydrophobicContact CZ-CE1 4.25Å; F113-F174 AromaticContact CZ-CZ 3.88Å; F113-F174 HydrophobicContact CZ-CZ 3.88Å
114	V	97.7	Very high	96.5	Very high	25 Å²	25	37.3 Å²	37.3	15%	0.152	18%	0.179	C	C	.	.	H	α-helix	trans	-60.8	-52.4	175.1	176.7	0	0	0	0	110.9	Y110 N111 D112 F116 Q117 E118 L132	Y110-V114 HydrophobicContact CD1-CG2 4.07Å; Y110-V114 HydrophobicContact CE1-CG2 3.41Å; Y110-V114 VanDerWaalsContact CE1-CG2 3.41Å; Y110-V114 HydrophobicContact CE2-CG2 4.43Å; Y110-V114 PolarHBondContact O-N 2.61Å; N111-V114 PolarHBondContact O-N 3.17Å; D112-V114 VanDerWaalsContact C-N 3.29Å; D112-V114 PolarHBondContact O-N 3.49Å; V114-F116 VanDerWaalsContact C-N 3.27Å; V114-F116 PolarHBondContact O-N 3.06Å; V114-Q117 PolarHBondContact O-N 2.71Å; V114-E118 WeakPolarHBondContact CG1-OE1 3.46Å; V114-E118 WeakPolarHBondContact O-CG 3.38Å; V114-E118 PolarHBondContact O-N 2.69Å; V114-L132 HydrophobicContact CB-CD1 4.3Å; V114-L132 HydrophobicContact CG2-CD1 3.84Å
115	V	97.4	Very high	96.5	Very high	10 Å²	10	37.7 Å²	37.7	6%	0.061	18%	0.181	C	C	.	.	H	α-helix	trans	-60	-38.8	176.2	173	0	0	0	0	111.4	N111 D112 E118 M119 Q183 L186 K187	N111-V115 PolarHBondContact O-N 3.24Å; D112-V115 PolarHBondContact O-N 3.43Å; V115-E118 PolarHBondContact O-N 3.09Å; V115-M119 WeakPolarHBondContact O-CG 3.04Å; V115-M119 PolarHBondContact O-N 3.43Å; V115-Q183 HydrophobicContact CB-CG 4.38Å; V115-Q183 HydrophobicContact CG1-CB 4.34Å; V115-Q183 HydrophobicContact CG2-CB 4.47Å; V115-Q183 HydrophobicContact CG2-CG 4.17Å; V115-L186 HydrophobicContact CG1-CB 4.43Å; V115-L186 HydrophobicContact CG1-CD1 4.37Å; V115-K187 HydrophobicContact CG1-CG 4.23Å
116	F	98.3	Very high	96.5	Very high	0 Å²	0	35.6 Å²	35.6	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-63.5	-44.3	175.9	178	-137.9	0	0	0	112.6	D112 F113 V114 M119 L120 F155 V159 V170 L171 F174 L186	D112-F116 WeakPolarHBondContact O-CB 3.44Å; D112-F116 PolarHBondContact O-N 3.31Å; F113-F116 PolarHBondContact O-N 2.71Å; V114-F116 VanDerWaalsContact C-N 3.27Å; V114-F116 PolarHBondContact O-N 3.06Å; F116-M119 PolarHBondContact O-N 3.23Å; F116-L120 HydrophobicContact CD1-CD1 4.45Å; F116-L120 HydrophobicContact CD2-CD1 4.26Å; F116-L120 HydrophobicContact CD2-CG 4.2Å; F116-L120 HydrophobicContact CE1-CD1 4.09Å; F116-L120 HydrophobicContact CE2-CD1 3.88Å; F116-L120 HydrophobicContact CE2-CD2 4.05Å; F116-L120 HydrophobicContact CE2-CG 3.87Å; F116-L120 HydrophobicContact CZ-CD1 3.78Å; F116-L120 HydrophobicContact CZ-CD2 4.39Å; F116-L120 HydrophobicContact CZ-CG 4.27Å; F116-L120 WeakPolarHBondContact O-CG 3.46Å; F116-L120 PolarHBondContact O-N 3.2Å; F116-F155 AromaticContact CD1-CE1 3.93Å; F116-F155 HydrophobicContact CD1-CE1 3.93Å; F116-F155 HydrophobicContact CD1-CZ 4.33Å; F116-F155 HydrophobicContact CE1-CE1 4.11Å; F116-V159 HydrophobicContact CE1-CG1 4.21Å; F116-V159 HydrophobicContact CZ-CG1 3.86Å; F116-V170 HydrophobicContact CD2-CG1 3.87Å; F116-V170 HydrophobicContact CE2-CG1 3.93Å; F116-L171 HydrophobicContact CE1-CD1 4.15Å; F116-L171 HydrophobicContact CE2-CB 4.44Å; F116-L171 HydrophobicContact CZ-CB 4.14Å; F116-L171 HydrophobicContact CZ-CD1 3.6Å; F116-L171 HydrophobicContact CZ-CG 4.49Å; F116-F174 HydrophobicContact CB-CD2 3.64Å; F116-F174 HydrophobicContact CB-CE2 3.9Å; F116-F174 HydrophobicContact CB-CG 4.23Å; F116-F174 HydrophobicContact CD1-CB 4.15Å; F116-F174 AromaticContact CD1-CD1 3.59Å; F116-F174 HydrophobicContact CD1-CD1 3.59Å; F116-F174 AromaticContact CD1-CD2 3.73Å; F116-F174 HydrophobicContact CD1-CD2 3.73Å; F116-F174 AromaticContact CD1-CE1 3.89Å; F116-F174 HydrophobicContact CD1-CE1 3.89Å; F116-F174 HydrophobicContact CD1-CE2 4.01Å; F116-F174 AromaticContact CD1-CG 3.51Å; F116-F174 HydrophobicContact CD1-CG 3.51Å; F116-F174 HydrophobicContact CD1-CZ 4.09Å; F116-F174 HydrophobicContact CD2-CB 3.96Å; F116-F174 HydrophobicContact CD2-CD2 4.32Å; F116-F174 HydrophobicContact CD2-CG 4.14Å; F116-F174 HydrophobicContact CE1-CB 4.16Å; F116-F174 AromaticContact CE1-CD1 3.63Å; F116-F174 HydrophobicContact CE1-CD1 3.63Å; F116-F174 HydrophobicContact CE1-CD2 4.48Å; F116-F174 HydrophobicContact CE1-CE1 4.17Å; F116-F174 AromaticContact CE1-CG 3.82Å; F116-F174 HydrophobicContact CE1-CG 3.82Å; F116-F174 HydrophobicContact CE2-CB 3.98Å; F116-F174 HydrophobicContact CE2-CG 4.4Å; F116-F174 HydrophobicContact CG-CB 4.06Å; F116-F174 HydrophobicContact CG-CD1 4.27Å; F116-F174 AromaticContact CG-CD2 3.64Å; F116-F174 HydrophobicContact CG-CD2 3.64Å; F116-F174 HydrophobicContact CG-CE2 4.17Å; F116-F174 AromaticContact CG-CG 3.7Å; F116-F174 HydrophobicContact CG-CG 3.7Å; F116-F174 HydrophobicContact CZ-CB 4.08Å; F116-F174 HydrophobicContact CZ-CD1 4.32Å; F116-F174 HydrophobicContact CZ-CG 4.25Å; F116-L186 HydrophobicContact CB-CD1 4.2Å; F116-L186 HydrophobicContact CD2-CD2 4.29Å
117	Q	98.2	Very high	96.5	Very high	36 Å²	36	35.9 Å²	35.9	17%	0.168	17%	0.166	C	C	.	.	H	α-helix	trans	-62.4	-42.1	174.2	-170.3	-162.8	30.6	0	0	111.8	F113 V114 M119 L120 L121 V129 P130 L132 F155	F113-Q117 WeakPolarHBondContact O-CB 3.47Å; F113-Q117 PolarHBondContact O-N 3.26Å; V114-Q117 PolarHBondContact O-N 2.71Å; Q117-M119 VanDerWaalsContact C-N 3.33Å; Q117-M119 PolarHBondContact O-N 2.97Å; Q117-L120 PolarHBondContact O-N 3.19Å; Q117-L121 HydrophobicContact CG-CD1 4.17Å; Q117-L121 WeakPolarHBondContact O-CB 3.34Å; Q117-L121 WeakPolarHBondContact O-CG 3.25Å; Q117-L121 PolarHBondContact O-N 2.76Å; Q117-V129 HydrophobicContact CG-CG1 4.04Å; Q117-P130 PolarHBondContact NE2-O 3.44Å; Q117-L132 HydrophobicContact CB-CD1 3.85Å; Q117-L132 HydrophobicContact CB-CG 4.28Å; Q117-L132 HydrophobicContact CG-CD1 4.39Å; Q117-L132 HydrophobicContact CG-CG 4.4Å; Q117-F155 HydrophobicContact CB-CE2 4.2Å; Q117-F155 HydrophobicContact CB-CZ 4.02Å; Q117-F155 HydrophobicContact CG-CE2 4.01Å; Q117-F155 HydrophobicContact CG-CZ 4.32Å
118	E	97.1	Very high	96.6	Very high	94 Å²	94	29.1 Å²	29.1	44%	0.439	14%	0.139	S	C	.	.	H	α-helix	trans	-58.6	-43.8	174.9	-72.3	168	178.3	0	0	111.3	V114 V115 L121 H122	V114-E118 WeakPolarHBondContact CG1-OE1 3.46Å; V114-E118 WeakPolarHBondContact O-CG 3.38Å; V114-E118 PolarHBondContact O-N 2.69Å; V115-E118 PolarHBondContact O-N 3.09Å; E118-L121 PolarHBondContact O-N 3.13Å; E118-H122 WeakPolarHBondContact O-CB 3.4Å; E118-H122 PolarHBondContact O-N 2.93Å
119	M	96.8	Very high	96.7	Very high	25 Å²	25	28.9 Å²	28.9	12%	0.123	14%	0.139	C	C	.	.	H	α-helix	trans	-69.3	-36.9	177.9	-63.7	-49.3	90.2	0	0	112.4	V115 F116 Q117 H122 K123 V170 L186 K187 A190	V115-M119 WeakPolarHBondContact O-CG 3.04Å; V115-M119 PolarHBondContact O-N 3.43Å; F116-M119 PolarHBondContact O-N 3.23Å; Q117-M119 VanDerWaalsContact C-N 3.33Å; Q117-M119 PolarHBondContact O-N 2.97Å; M119-H122 PolarHBondContact O-N 3.22Å; M119-K123 VanDerWaalsContact O-CB 3.31Å; M119-K123 WeakPolarHBondContact O-CB 3.43Å; M119-K123 PolarHBondContact O-N 3.26Å; M119-V170 HydrophobicContact CB-CG1 4.05Å; M119-L186 HydrophobicContact CG-CB 4.23Å; M119-K187 HydrophobicContact CE-CG 4.38Å; M119-K187 HydrophobicContact SD-CB 4.37Å; M119-K187 HydrophobicContact SD-CG 3.96Å; M119-A190 HydrophobicContact CB-CB 4.13Å; M119-A190 HydrophobicContact CG-CB 4.07Å; M119-A190 HydrophobicContact SD-CB 3.58Å; M119-A190 VanDerWaalsContact SD-CB 3.58Å
120	L	97	Very high	96.9	Very high	1 Å²	1	25.5 Å²	25.5	1%	0.005	13%	0.126	C	C	.	.	H	α-helix	trans	-62.6	-45.2	172.4	-71.1	170.9	0	0	0	111.6	F116 Q117 H122 K123 F124 V129 F155 V159 F165	F116-L120 HydrophobicContact CD1-CD1 4.45Å; F116-L120 HydrophobicContact CD2-CD1 4.26Å; F116-L120 HydrophobicContact CD2-CG 4.2Å; F116-L120 HydrophobicContact CE1-CD1 4.09Å; F116-L120 HydrophobicContact CE2-CD1 3.88Å; F116-L120 HydrophobicContact CE2-CD2 4.05Å; F116-L120 HydrophobicContact CE2-CG 3.87Å; F116-L120 HydrophobicContact CZ-CD1 3.78Å; F116-L120 HydrophobicContact CZ-CD2 4.39Å; F116-L120 HydrophobicContact CZ-CG 4.27Å; F116-L120 WeakPolarHBondContact O-CG 3.46Å; F116-L120 PolarHBondContact O-N 3.2Å; Q117-L120 PolarHBondContact O-N 3.19Å; L120-H122 VanDerWaalsContact C-N 3.33Å; L120-H122 PolarHBondContact O-N 2.93Å; L120-K123 PolarHBondContact O-N 2.95Å; L120-F124 HydrophobicContact CD2-CD2 4.26Å; L120-F124 HydrophobicContact CD2-CE2 4.42Å; L120-F124 WeakPolarHBondContact O-CA 3.32Å; L120-F124 WeakPolarHBondContact O-CB 3.26Å; L120-F124 PolarHBondContact O-N 2.96Å; L120-V129 HydrophobicContact CB-CG1 3.79Å; L120-V129 HydrophobicContact CB-CG2 4.01Å; L120-V129 HydrophobicContact CD1-CG1 4.22Å; L120-F155 HydrophobicContact CD1-CZ 4.29Å; L120-V159 HydrophobicContact CD1-CG1 3.74Å; L120-V159 HydrophobicContact CD1-CG2 3.89Å; L120-V159 HydrophobicContact CD2-CG1 4.38Å; L120-F165 HydrophobicContact CD2-CB 4.44Å; L120-F165 HydrophobicContact CD2-CD1 4.27Å; L120-F165 HydrophobicContact CD2-CG 4.23Å
121	L	96.5	Very high	97	Very high	59 Å²	59	26.7 Å²	26.7	31%	0.309	14%	0.141	S	C	.	.	H	α-helix	trans	-65.9	-33.5	177.3	-75.5	168.5	0	0	0	112.9	Q117 E118 V129	Q117-L121 HydrophobicContact CG-CD1 4.17Å; Q117-L121 WeakPolarHBondContact O-CB 3.34Å; Q117-L121 WeakPolarHBondContact O-CG 3.25Å; Q117-L121 PolarHBondContact O-N 2.76Å; E118-L121 PolarHBondContact O-N 3.13Å; L121-V129 HydrophobicContact CD2-CB 3.81Å; L121-V129 HydrophobicContact CD2-CG1 4.18Å; L121-V129 HydrophobicContact CD2-CG2 4.07Å; L121-V129 HydrophobicContact CG-CB 4.2Å; L121-V129 HydrophobicContact CG-CG1 4.03Å; L121-V129 HydrophobicContact CG-CG2 4.42Å
122	H	94.8	Very high	97.2	Very high	102 Å²	102	25.3 Å²	25.3	47%	0.472	13%	0.134	S	C	.	.	H	α-helix	trans	-71.4	-44.3	176.2	-177	58.7	0	0	0	112.2	E118 M119 L120	E118-H122 WeakPolarHBondContact O-CB 3.4Å; E118-H122 PolarHBondContact O-N 2.93Å; M119-H122 PolarHBondContact O-N 3.22Å; L120-H122 VanDerWaalsContact C-N 3.33Å; L120-H122 PolarHBondContact O-N 2.93Å
123	K	94.9	Very high	97	Very high	15 Å²	15	25.6 Å²	25.6	7%	0.065	14%	0.136	C	C	.	.	H	α-helix	trans	-80	-35.6	-176.5	-165	173	-173	-178.8	0	112.9	M119 L120 P125 D168 V170 D195 E196	M119-K123 VanDerWaalsContact O-CB 3.31Å; M119-K123 WeakPolarHBondContact O-CB 3.43Å; M119-K123 PolarHBondContact O-N 3.26Å; L120-K123 PolarHBondContact O-N 2.95Å; K123-P125 WeakPolarHBondContact O-CD 3.42Å; K123-D168 VanDerWaalsContact CE-OD2 3.27Å; K123-D168 WeakPolarHBondContact CE-OD2 3.41Å; K123-D168 IonicContact NZ-OD1 2.68Å; K123-D168 PolarHBondContact NZ-OD1 3.41Å; K123-D168 IonicContact NZ-OD2 2.69Å; K123-D168 PolarHBondContact NZ-OD2 3.35Å; K123-V170 HydrophobicContact CD-CG2 4.4Å; K123-D195 CarbonylContact O-C 3.49Å; K123-D195 WeakPolarHBondContact O-CA 3.45Å; K123-E196 WeakPolarHBondContact O-CB 3.42Å; K123-E196 PolarHBondContact O-N 3.46Å
124	F	96.4	Very high	96.5	Very high	18 Å²	18	30 Å²	30	8%	0.079	17%	0.165	C	C	.	.			trans	-124.7	60.3	-175.7	-55.8	-78.6	0	0	0	113	L120 Y126 R127 L164 F165 D168 E196	L120-F124 HydrophobicContact CD2-CD2 4.26Å; L120-F124 HydrophobicContact CD2-CE2 4.42Å; L120-F124 WeakPolarHBondContact O-CA 3.32Å; L120-F124 WeakPolarHBondContact O-CB 3.26Å; L120-F124 PolarHBondContact O-N 2.96Å; F124-Y126 PolarHBondContact O-N 3.06Å; F124-Y126 VanDerWaalsContact O-N 3.13Å; F124-R127 HydrophobicContact CB-CB 4.06Å; F124-R127 HydrophobicContact CB-CG 3.89Å; F124-R127 HydrophobicContact CD1-CG 4.46Å; F124-R127 PolarHBondContact O-N 2.86Å; F124-L164 HydrophobicContact CE1-CB 4.47Å; F124-F165 HydrophobicContact CB-CD1 4.46Å; F124-F165 HydrophobicContact CB-CE1 3.62Å; F124-F165 HydrophobicContact CB-CZ 4.4Å; F124-F165 HydrophobicContact CD1-CD1 4.42Å; F124-F165 HydrophobicContact CD1-CE1 4.2Å; F124-F165 AromaticContact CD2-CD1 3.68Å; F124-F165 HydrophobicContact CD2-CD1 3.68Å; F124-F165 AromaticContact CD2-CE1 3.69Å; F124-F165 HydrophobicContact CD2-CE1 3.69Å; F124-F165 AromaticContact CE2-CD1 3.92Å; F124-F165 HydrophobicContact CE2-CD1 3.92Å; F124-F165 HydrophobicContact CE2-CE1 4.37Å; F124-F165 AromaticContact CG-CD1 3.96Å; F124-F165 HydrophobicContact CG-CD1 3.96Å; F124-F165 AromaticContact CG-CE1 3.58Å; F124-F165 HydrophobicContact CG-CE1 3.58Å; F124-F165 HydrophobicContact CZ-CD1 4.39Å; F124-D168 HydrophobicContact CE2-CB 4.24Å; F124-D168 HydrophobicContact CZ-CB 4.1Å; F124-E196 WeakPolarHBondContact CA-OE1 3.47Å; F124-E196 HydrophobicContact CD1-CB 4Å; F124-E196 HydrophobicContact CE1-CB 4.49Å
125	P	96.3	Very high	95.8	Very high	31 Å²	31	35.2 Å²	35.2	20%	0.201	19%	0.185	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.2	-19.8	-175.8	26.9	-35.7	0	0	0	113.9	K123 D195 R333	K123-P125 WeakPolarHBondContact O-CD 3.42Å; P125-D195 HydrophobicContact CG-CB 4.21Å; P125-R333 PolarHBondContact O-NE 2.92Å
126	Y	97.6	Very high	94.7	Very high	10 Å²	10	41.3 Å²	41.3	4%	0.039	21%	0.207	C	C	.	.	T	Hydrogen-bonded Turn	trans	-100.4	13.8	-176.4	-44.3	-69	0	0	0	113.4	F124 E196 F197 L330 V338 R389 F392 S393 C396	F124-Y126 PolarHBondContact O-N 3.06Å; F124-Y126 VanDerWaalsContact O-N 3.13Å; Y126-E196 WeakPolarHBondContact CA-OE1 3.46Å; Y126-E196 WeakPolarHBondContact CB-OE1 3.34Å; Y126-E196 HydrophobicContact CD2-CG 3.63Å; Y126-E196 WeakPolarHBondContact CD2-OE1 3.43Å; Y126-E196 HydrophobicContact CE2-CG 4.18Å; Y126-E196 PolarHBondContact N-OE1 2.9Å; Y126-F197 HydrophobicContact CE2-CB 3.86Å; Y126-L330 WeakPolarHBondContact O-CD1 3.29Å; Y126-V338 HydrophobicContact CD1-CG2 4.24Å; Y126-V338 HydrophobicContact CE1-CG2 3.71Å; Y126-R389 PolarHBondContact OH-NH1 3.2Å; Y126-F392 AromaticContact CD2-CD1 3.78Å; Y126-F392 HydrophobicContact CD2-CD1 3.78Å; Y126-F392 AromaticContact CD2-CE1 3.65Å; Y126-F392 HydrophobicContact CD2-CE1 3.65Å; Y126-F392 AromaticContact CE2-CD1 3.72Å; Y126-F392 HydrophobicContact CE2-CD1 3.72Å; Y126-F392 AromaticContact CE2-CE1 3.81Å; Y126-F392 HydrophobicContact CE2-CE1 3.81Å; Y126-S393 WeakPolarHBondContact CD1-OG 3.47Å; Y126-C396 WeakPolarHBondContact O-CB 3.27Å
127	R	97.9	Very high	92.7	Very high	10 Å²	10	49.9 Å²	49.9	4%	0.038	25%	0.25	C	C	.	.	S	Bend	trans	-118.6	164.3	-176.9	-56.4	-61.4	170.2	169.2	-2.8	113.9	F124 V129 L164 F165 E196 R333 C396 E400	F124-R127 HydrophobicContact CB-CB 4.06Å; F124-R127 HydrophobicContact CB-CG 3.89Å; F124-R127 HydrophobicContact CD1-CG 4.46Å; F124-R127 PolarHBondContact O-N 2.86Å; R127-V129 PolarHBondContact O-N 2.91Å; R127-L164 HydrophobicContact CG-CD1 4.26Å; R127-L164 VanDerWaalsContact NE-CD1 3.29Å; R127-F165 HydrophobicContact CB-CE1 3.76Å; R127-F165 HydrophobicContact CB-CZ 3.55Å; R127-F165 HydrophobicContact CG-CE1 4.15Å; R127-F165 HydrophobicContact CG-CZ 4.42Å; R127-E196 WeakPolarHBondContact CG-OE2 3.14Å; R127-E196 IonicContact CZ-OE2 2.71Å; R127-E196 IonicContact NE-OE2 3.67Å; R127-E196 PolarHBondContact NE-OE2 3.28Å; R127-E196 IonicContact NH2-OE2 3.5Å; R127-R333 PolarHBondContact O-NH2 3.32Å; R127-C396 PolarHBondContact NH2-SG 2.91Å; R127-E400 VanDerWaalsContact CD-CD 3.46Å; R127-E400 WeakPolarHBondContact CD-OE1 3.49Å; R127-E400 IonicContact CZ-OE1 3.16Å; R127-E400 IonicContact NE-OE1 3.71Å; R127-E400 IonicContact NH1-OE1 3.22Å; R127-E400 PolarHBondContact NH1-OE1 3.07Å
128	M	98	Very high	90.6	Very high	4 Å²	4	56 Å²	56	2%	0.02	28%	0.283	C	S	.	.			trans	-76.8	67.1	177.3	-68.3	-171.1	-61.7	0	0	112.2	P130 L323 Y327 L330 E400 L403 I404	M128-P130 WeakPolarHBondContact O-CD 3.39Å; M128-L323 HydrophobicContact CE-CD1 3.98Å; M128-L323 HydrophobicContact SD-CD1 4.28Å; M128-Y327 HydrophobicContact SD-CD2 3.81Å; M128-Y327 HydrophobicContact SD-CG 4.22Å; M128-L330 HydrophobicContact CG-CD2 3.99Å; M128-E400 WeakPolarHBondContact CB-OE2 3.42Å; M128-E400 HydrophobicContact CE-CB 3.93Å; M128-E400 WeakPolarHBondContact CE-O 3.49Å; M128-E400 HydrophobicContact CG-CB 3.95Å; M128-E400 HydrophobicContact CG-CG 4.18Å; M128-E400 WeakPolarHBondContact CG-OE2 3.41Å; M128-E400 PolarHBondContact N-OE2 2.77Å; M128-E400 HydrophobicContact SD-CB 4.1Å; M128-L403 HydrophobicContact CE-CB 3.9Å; M128-L403 HydrophobicContact CE-CD2 3.72Å; M128-L403 HydrophobicContact CE-CG 3.95Å; M128-I404 HydrophobicContact CE-CD1 3.97Å; M128-I404 HydrophobicContact CE-CG1 4.16Å; M128-I404 HydrophobicContact SD-CD1 3.61Å; M128-I404 HydrophobicContact SD-CG1 3.86Å
129	V	98.4	Very high	88.8	Confident	2 Å²	2	54 Å²	54	1%	0.012	29%	0.287	C	S	.	.	P	Polyproline II helix	trans	-69.4	121.9	167.1	-173.3	0	0	0	0	108.9	Q117 L120 L121 R127 F165	Q117-V129 HydrophobicContact CG-CG1 4.04Å; L120-V129 HydrophobicContact CB-CG1 3.79Å; L120-V129 HydrophobicContact CB-CG2 4.01Å; L120-V129 HydrophobicContact CD1-CG1 4.22Å; L121-V129 HydrophobicContact CD2-CB 3.81Å; L121-V129 HydrophobicContact CD2-CG1 4.18Å; L121-V129 HydrophobicContact CD2-CG2 4.07Å; L121-V129 HydrophobicContact CG-CB 4.2Å; L121-V129 HydrophobicContact CG-CG1 4.03Å; L121-V129 HydrophobicContact CG-CG2 4.42Å; R127-V129 PolarHBondContact O-N 2.91Å; V129-F165 HydrophobicContact CG2-CE1 4.47Å; V129-F165 HydrophobicContact CG2-CE2 4.29Å; V129-F165 HydrophobicContact CG2-CZ 3.74Å
130	P	98.3	Very high	87.3	Confident	3 Å²	3	54.7 Å²	54.7	2%	0.019	30%	0.297	C	S	.	.	P	Polyproline II helix	trans	-74.5	159.4	-176.6	-14.6	29.7	0	0	0	114.1	Q117 M128 F155 L158 V159 S326	Q117-P130 PolarHBondContact NE2-O 3.44Å; M128-P130 WeakPolarHBondContact O-CD 3.39Å; P130-F155 HydrophobicContact CB-CD2 3.97Å; P130-F155 HydrophobicContact CG-CD2 4.42Å; P130-F155 WeakPolarHBondContact O-CE2 3.36Å; P130-L158 HydrophobicContact CB-CD1 4.19Å; P130-L158 HydrophobicContact CG-CB 3.74Å; P130-L158 HydrophobicContact CG-CD1 4.01Å; P130-V159 HydrophobicContact CG-CG2 4.21Å; P130-S326 WeakPolarHBondContact CA-OG 3.33Å; P130-S326 WeakPolarHBondContact CB-OG 3.49Å
131	A	96.4	Very high	86.5	Confident	50 Å²	50	59 Å²	59	41%	0.413	32%	0.319	S	S	.	.	P	Polyproline II helix	trans	-71.5	153.4	173.4	0	0	0	0	0	112.1
132	L	97.3	Very high	85.9	Confident	26 Å²	26	65.6 Å²	65.6	14%	0.136	34%	0.34	C	S	.	.	P	Polyproline II helix	trans	-97.9	150.9	169.5	-72.4	176	0	0	0	110.8	F113 V114 Q117 L152 F155	F113-L132 HydrophobicContact CB-CD1 4.27Å; F113-L132 HydrophobicContact CB-CD2 4.07Å; V114-L132 HydrophobicContact CB-CD1 4.3Å; V114-L132 HydrophobicContact CG2-CD1 3.84Å; Q117-L132 HydrophobicContact CB-CD1 3.85Å; Q117-L132 HydrophobicContact CB-CG 4.28Å; Q117-L132 HydrophobicContact CG-CD1 4.39Å; Q117-L132 HydrophobicContact CG-CG 4.4Å; L132-L152 HydrophobicContact CD2-CD2 3.8Å; L132-F155 HydrophobicContact CD2-CB 4.3Å; L132-F155 HydrophobicContact CD2-CD1 3.81Å; L132-F155 HydrophobicContact CD2-CD2 3.59Å; L132-F155 HydrophobicContact CD2-CE1 4.01Å; L132-F155 HydrophobicContact CD2-CE2 3.81Å; L132-F155 HydrophobicContact CD2-CG 3.62Å; L132-F155 HydrophobicContact CD2-CZ 4.02Å; L132-F155 HydrophobicContact CG-CD2 4.23Å; L132-F155 HydrophobicContact CG-CE2 4.19Å
133	P	93.6	Very high	85.5	Confident	17 Å²	17	66.5 Å²	66.5	11%	0.11	35%	0.345	C	S	.	.	P	Polyproline II helix	trans	-60.6	148.3	170.4	27.5	-35.6	0	0	0	110.8	Y110 R148 A151 L152	Y110-P133 HydrophobicContact CE2-CG 4.29Å; Y110-P133 VanDerWaalsContact CE2-O 3.31Å; Y110-P133 WeakPolarHBondContact CE2-O 3.29Å; Y110-P133 PolarHBondContact OH-O 2.99Å; P133-R148 HydrophobicContact CG-CB 4.43Å; P133-R148 HydrophobicContact CG-CG 3.89Å; P133-A151 HydrophobicContact CB-CB 3.69Å; P133-A151 HydrophobicContact CG-CB 3.72Å; P133-L152 HydrophobicContact CG-CD2 4.02Å; P133-L152 HydrophobicContact CG-CG 4.17Å
134	P	86.8	Confident	85.2	Confident	93 Å²	93	68.2 Å²	68.2	60%	0.604	35%	0.353	S	S	*	.	P	Polyproline II helix	trans	-58.5	143.2	-168.1	21.3	-33.3	0	0	0	114	R136 R148	P134-R136 PolarHBondContact O-N 3.5Å; P134-R148 PolarHBondContact O-NH2 2.73Å
135	K	83.9	Confident	84.8	Confident	133 Å²	133	68.8 Å²	68.8	58%	0.578	36%	0.356	S	S	*	.	P	Polyproline II helix	trans	-63.6	131.4	165.2	-158.5	168.7	-172.8	175.5	0	107.7	Y110 M137	Y110-K135 HydrophobicContact CE1-CB 4.17Å; Y110-K135 HydrophobicContact CE1-CD 4.48Å; Y110-K135 HydrophobicContact CE1-CG 3.97Å; K135-M137 PolarHBondContact O-N 3.11Å
136	R	73.9	Confident	84.6	Confident	139 Å²	139	69.7 Å²	69.7	53%	0.525	36%	0.358	S	S	.	.	P	Polyproline II helix	trans	-62.9	130.2	-166.6	-177.8	-178	70.2	175.1	1.3	111.3	P134 G139 F144	P134-R136 PolarHBondContact O-N 3.5Å; R136-G139 WeakPolarHBondContact CD-O 3.33Å; R136-G139 WeakPolarHBondContact CG-O 3.35Å; R136-F144 HydrophobicContact CB-CE1 3.8Å; R136-F144 HydrophobicContact CB-CZ 3.79Å; R136-F144 HydrophobicContact CG-CE1 3.88Å; R136-F144 HydrophobicContact CG-CZ 4.06Å
137	M	57.7	Low	84.3	Confident	180 Å²	180	71.8 Å²	71.8	89%	0.887	38%	0.377	S	S	*	.	S	Bend	trans	-83.8	-60.8	173.9	-67.9	-66.1	174	0	0	111.4	K135	K135-M137 PolarHBondContact O-N 3.11Å
138	L	53.7	Low	84.1	Confident	165 Å²	165	72.4 Å²	72.4	86%	0.864	38%	0.379	S	S	*	.	S	Bend	trans	-143.1	151.2	173.4	-70.9	173	0	0	0	108.7
139	G	58.2	Low	84	Confident	51 Å²	51	73.3 Å²	73.3	53%	0.526	38%	0.382	S	S	.	.			trans	66.2	123.2	173.4	0	0	0	0	0	115.5	R136	R136-G139 WeakPolarHBondContact CD-O 3.33Å; R136-G139 WeakPolarHBondContact CG-O 3.35Å
140	A	65.1	Low	84	Confident	40 Å²	40	75 Å²	75	33%	0.331	39%	0.388	S	S	.	.			trans	-114.1	91.8	157.5	0	0	0	0	0	106.8	F144 I145	A140-F144 HydrophobicContact CB-CD1 4.19Å; A140-I145 HydrophobicContact CB-CD1 4.14Å; A140-I145 HydrophobicContact CB-CG1 4.11Å
141	D	80.8	Confident	83.9	Confident	90 Å²	90	75.5 Å²	75.5	48%	0.481	39%	0.393	S	S	.	.			trans	-69.5	174.5	157.7	53.5	37.5	0	0	0	109.6	E143 F144 I145	D141-E143 VanDerWaalsContact C-N 3.27Å; D141-E143 PolarHBondContact O-N 3.41Å; D141-F144 WeakPolarHBondContact OD1-CB 3.44Å; D141-F144 PolarHBondContact OD1-N 2.87Å; D141-I145 WeakPolarHBondContact O-CG1 3.45Å; D141-I145 PolarHBondContact O-N 2.84Å
142	R	84.7	Confident	84	Confident	198 Å²	198	73.1 Å²	73.1	75%	0.747	37%	0.373	S	S	*	.	H	α-helix	trans	-70.7	-32.7	-175.9	178.1	-174	-177.4	-169.4	1.1	110.8	I145 E146	R142-I145 PolarHBondContact O-N 3.01Å; R142-E146 PolarHBondContact O-N 3.21Å
143	E	85.8	Confident	84.1	Confident	121 Å²	121	74.3 Å²	74.3	57%	0.565	38%	0.377	S	S	*	.	H	α-helix	trans	-66.5	-45.9	-177.1	-65.5	58.3	-131	0	0	110.1	D141 E146 A147	D141-E143 VanDerWaalsContact C-N 3.27Å; D141-E143 PolarHBondContact O-N 3.41Å; E143-E146 PolarHBondContact O-N 3.48Å; E143-A147 VanDerWaalsContact O-CB 3.25Å; E143-A147 WeakPolarHBondContact O-CB 3.31Å; E143-A147 PolarHBondContact O-N 3.01Å
144	F	88.3	Confident	84.3	Confident	52 Å²	52	74.9 Å²	74.9	23%	0.228	38%	0.377	C	S	.	.	H	α-helix	trans	-63.5	-38.7	172.5	178.3	-99.7	0	0	0	112.8	R136 A140 D141 R148	R136-F144 HydrophobicContact CB-CE1 3.8Å; R136-F144 HydrophobicContact CB-CZ 3.79Å; R136-F144 HydrophobicContact CG-CE1 3.88Å; R136-F144 HydrophobicContact CG-CZ 4.06Å; A140-F144 HydrophobicContact CB-CD1 4.19Å; D141-F144 WeakPolarHBondContact OD1-CB 3.44Å; D141-F144 PolarHBondContact OD1-N 2.87Å; F144-R148 VanDerWaalsContact CZ-NH2 3.29Å; F144-R148 VanDerWaalsContact O-CB 3.25Å; F144-R148 WeakPolarHBondContact O-CB 3.48Å; F144-R148 PolarHBondContact O-N 3.07Å
145	I	88.8	Confident	84.9	Confident	29 Å²	29	70.5 Å²	70.5	15%	0.149	35%	0.349	C	S	.	.	H	α-helix	trans	-66.2	-43.8	177.3	-66.6	169.6	0	0	0	110.6	L81 V93 A140 D141 R142 R148 R149	L81-I145 HydrophobicContact CD1-CG2 3.67Å; L81-I145 HydrophobicContact CD2-CG2 3.75Å; L81-I145 HydrophobicContact CG-CG2 4.35Å; V93-I145 HydrophobicContact CG1-CG2 4.16Å; V93-I145 HydrophobicContact CG2-CD1 4.24Å; A140-I145 HydrophobicContact CB-CD1 4.14Å; A140-I145 HydrophobicContact CB-CG1 4.11Å; D141-I145 WeakPolarHBondContact O-CG1 3.45Å; D141-I145 PolarHBondContact O-N 2.84Å; R142-I145 PolarHBondContact O-N 3.01Å; I145-R148 PolarHBondContact O-N 3.16Å; I145-R149 WeakPolarHBondContact O-CB 3.47Å; I145-R149 PolarHBondContact O-N 2.99Å
146	E	90.9	Very high	85.6	Confident	51 Å²	51	64.2 Å²	64.2	24%	0.238	32%	0.321	C	S	.	.	H	α-helix	trans	-68.3	-45.3	177.3	174.8	56.8	-164.8	0	0	112.1	R142 E143 R148 R149 R150	R142-E146 PolarHBondContact O-N 3.21Å; E143-E146 PolarHBondContact O-N 3.48Å; E146-R148 VanDerWaalsContact C-N 3.3Å; E146-R148 PolarHBondContact O-N 3.48Å; E146-R149 WeakPolarHBondContact O-CB 3.11Å; E146-R149 PolarHBondContact O-N 2.97Å; E146-R149 VanDerWaalsContact O-N 3.12Å; E146-R149 IonicContact OE1-CZ 3.78Å; E146-R149 IonicContact OE1-NE 2.85Å; E146-R149 PolarHBondContact OE1-NE 3.46Å; E146-R149 IonicContact OE1-NH2 2.9Å; E146-R149 PolarHBondContact OE1-NH2 3.16Å; E146-R149 IonicContact OE2-CZ 3.75Å; E146-R149 IonicContact OE2-NE 3.83Å; E146-R149 PolarHBondContact OE2-NE 3.42Å; E146-R149 IonicContact OE2-NH2 3.96Å; E146-R149 PolarHBondContact OE2-NH2 2.71Å; E146-R150 WeakPolarHBondContact O-CG 3.29Å; E146-R150 PolarHBondContact O-N 2.93Å; E146-R150 IonicContact OE1-CZ 2.69Å; E146-R150 IonicContact OE1-NE 2.69Å; E146-R150 PolarHBondContact OE1-NE 3.01Å; E146-R150 IonicContact OE1-NH2 3.97Å
147	A	92.3	Very high	86.8	Confident	53 Å²	53	58.1 Å²	58.1	44%	0.438	30%	0.299	S	S	.	.	H	α-helix	trans	-59.3	-40.7	174.7	0	0	0	0	0	111.8	E143 A151	E143-A147 VanDerWaalsContact O-CB 3.25Å; E143-A147 WeakPolarHBondContact O-CB 3.31Å; E143-A147 PolarHBondContact O-N 3.01Å; A147-A151 WeakPolarHBondContact O-CB 3.49Å; A147-A151 PolarHBondContact O-N 3.1Å
148	R	94.6	Very high	88.7	Confident	24 Å²	24	50.1 Å²	50.1	9%	0.091	26%	0.26	C	S	.	.	H	α-helix	trans	-62.8	-48.8	171	172.5	177.5	-77.4	159.7	-0.6	111.6	Y95 Y110 P133 P134 F144 I145 E146 R150 A151 L152	Y95-R148 WeakPolarHBondContact OH-CD 3.3Å; Y110-R148 HydrophobicContact CD2-CG 4.35Å; P133-R148 HydrophobicContact CG-CB 4.43Å; P133-R148 HydrophobicContact CG-CG 3.89Å; P134-R148 PolarHBondContact O-NH2 2.73Å; F144-R148 VanDerWaalsContact CZ-NH2 3.29Å; F144-R148 VanDerWaalsContact O-CB 3.25Å; F144-R148 WeakPolarHBondContact O-CB 3.48Å; F144-R148 PolarHBondContact O-N 3.07Å; I145-R148 PolarHBondContact O-N 3.16Å; E146-R148 VanDerWaalsContact C-N 3.3Å; E146-R148 PolarHBondContact O-N 3.48Å; R148-R150 VanDerWaalsContact C-N 3.31Å; R148-R150 PolarHBondContact O-N 3.39Å; R148-A151 PolarHBondContact O-N 3.32Å; R148-L152 HydrophobicContact CG-CD1 3.88Å; R148-L152 HydrophobicContact CG-CG 4.08Å; R148-L152 WeakPolarHBondContact O-CG 3.3Å; R148-L152 PolarHBondContact O-N 3.26Å
149	R	95.7	Very high	90.9	Very high	22 Å²	22	42.3 Å²	42.3	8%	0.083	22%	0.219	C	C	.	.	H	α-helix	trans	-55.4	-47.5	-179.9	-176	-158.9	69.8	92.6	-12.3	111.1	V79 E80 Y95 I145 E146 L152 K153	V79-R149 HydrophobicContact CG1-CG 4.26Å; V79-R149 WeakPolarHBondContact O-CD 3.39Å; V79-R149 WeakPolarHBondContact O-CG 3.26Å; V79-R149 PolarHBondContact O-NH1 2.8Å; E80-R149 IonicContact OE1-NH1 3.65Å; E80-R149 PolarHBondContact OE1-NH1 3.28Å; E80-R149 IonicContact OE2-CZ 2.82Å; E80-R149 IonicContact OE2-NE 3.9Å; E80-R149 IonicContact OE2-NH1 2.71Å; E80-R149 PolarHBondContact OE2-NH1 2.68Å; Y95-R149 HydrophobicContact CD1-CB 4.38Å; Y95-R149 HydrophobicContact CD1-CG 4.15Å; Y95-R149 HydrophobicContact CE1-CB 4.01Å; Y95-R149 HydrophobicContact CE1-CG 4.28Å; I145-R149 WeakPolarHBondContact O-CB 3.47Å; I145-R149 PolarHBondContact O-N 2.99Å; E146-R149 WeakPolarHBondContact O-CB 3.11Å; E146-R149 PolarHBondContact O-N 2.97Å; E146-R149 VanDerWaalsContact O-N 3.12Å; E146-R149 IonicContact OE1-CZ 3.78Å; E146-R149 IonicContact OE1-NE 2.85Å; E146-R149 PolarHBondContact OE1-NE 3.46Å; E146-R149 IonicContact OE1-NH2 2.9Å; E146-R149 PolarHBondContact OE1-NH2 3.16Å; E146-R149 IonicContact OE2-CZ 3.75Å; E146-R149 IonicContact OE2-NE 3.83Å; E146-R149 PolarHBondContact OE2-NE 3.42Å; E146-R149 IonicContact OE2-NH2 3.96Å; E146-R149 PolarHBondContact OE2-NH2 2.71Å; R149-L152 PolarHBondContact O-N 2.78Å; R149-K153 WeakPolarHBondContact O-CB 3.43Å; R149-K153 PolarHBondContact O-N 3.06Å
150	R	96.6	Very high	92.8	Very high	38 Å²	38	39.9 Å²	39.9	14%	0.143	19%	0.194	C	C	.	.	H	α-helix	trans	-56.8	-50.7	174	-71.1	171.4	-174	-177.5	-6.1	112.2	E146 R148 L152 K153 R154 E310 E315	E146-R150 WeakPolarHBondContact O-CG 3.29Å; E146-R150 PolarHBondContact O-N 2.93Å; E146-R150 IonicContact OE1-CZ 2.69Å; E146-R150 IonicContact OE1-NE 2.69Å; E146-R150 PolarHBondContact OE1-NE 3.01Å; E146-R150 IonicContact OE1-NH2 3.97Å; R148-R150 VanDerWaalsContact C-N 3.31Å; R148-R150 PolarHBondContact O-N 3.39Å; R150-L152 PolarHBondContact O-N 2.91Å; R150-K153 WeakPolarHBondContact O-CA 3.43Å; R150-K153 VanDerWaalsContact O-CB 3.26Å; R150-K153 WeakPolarHBondContact O-CB 3.29Å; R150-K153 PolarHBondContact O-N 3.35Å; R150-K153 VanDerWaalsContact O-N 3.12Å; R150-R154 WeakPolarHBondContact O-CG 3.44Å; R150-R154 PolarHBondContact O-N 2.71Å; R150-E310 IonicContact CZ-OE1 3.97Å; R150-E310 IonicContact CZ-OE2 3.14Å; R150-E310 IonicContact NH1-OE1 2.69Å; R150-E310 PolarHBondContact NH1-OE1 3.4Å; R150-E310 IonicContact NH1-OE2 3.19Å; R150-E310 IonicContact NH2-OE1 3.63Å; R150-E310 PolarHBondContact NH2-OE1 3.11Å; R150-E310 IonicContact NH2-OE2 3.86Å; R150-E310 PolarHBondContact NH2-OE2 3.4Å; R150-E315 WeakPolarHBondContact CB-OE2 3.49Å
151	A	97.9	Very high	94.4	Very high	13 Å²	13	39.2 Å²	39.2	11%	0.107	18%	0.183	C	C	.	.	H	α-helix	trans	-63.2	-38.2	177.9	0	0	0	0	0	113.1	P133 A147 R148 K153 R154 F155	P133-A151 HydrophobicContact CB-CB 3.69Å; P133-A151 HydrophobicContact CG-CB 3.72Å; A147-A151 WeakPolarHBondContact O-CB 3.49Å; A147-A151 PolarHBondContact O-N 3.1Å; R148-A151 PolarHBondContact O-N 3.32Å; A151-K153 VanDerWaalsContact C-N 3.34Å; A151-R154 PolarHBondContact O-N 2.88Å; A151-F155 WeakPolarHBondContact O-CB 3.44Å; A151-F155 PolarHBondContact O-N 3.38Å
152	L	98.5	Very high	95.2	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-63.7	-39	172.4	-67.4	178.3	0	0	0	111.8	V79 Y95 Y110 F113 L132 P133 R148 R149 R150 V156	V79-L152 HydrophobicContact CG1-CB 4.25Å; Y95-L152 HydrophobicContact CD2-CD1 3.84Å; Y95-L152 HydrophobicContact CE1-CD1 4.46Å; Y95-L152 HydrophobicContact CE2-CD1 3.54Å; Y95-L152 HydrophobicContact CG-CD1 4.43Å; Y110-L152 HydrophobicContact CD2-CD1 4.5Å; Y110-L152 HydrophobicContact CD2-CD2 4.28Å; F113-L152 HydrophobicContact CB-CD2 4.02Å; F113-L152 HydrophobicContact CD1-CB 4.5Å; F113-L152 HydrophobicContact CD1-CD2 3.83Å; F113-L152 HydrophobicContact CD2-CD1 4.1Å; F113-L152 HydrophobicContact CD2-CD2 4.15Å; F113-L152 HydrophobicContact CE1-CB 4.08Å; F113-L152 HydrophobicContact CE1-CD2 4.25Å; F113-L152 HydrophobicContact CE2-CD1 3.97Å; F113-L152 HydrophobicContact CG-CD2 3.76Å; F113-L152 HydrophobicContact CZ-CB 4.17Å; F113-L152 HydrophobicContact CZ-CD1 4.28Å; L132-L152 HydrophobicContact CD2-CD2 3.8Å; P133-L152 HydrophobicContact CG-CD2 4.02Å; P133-L152 HydrophobicContact CG-CG 4.17Å; R148-L152 HydrophobicContact CG-CD1 3.88Å; R148-L152 HydrophobicContact CG-CG 4.08Å; R148-L152 WeakPolarHBondContact O-CG 3.3Å; R148-L152 PolarHBondContact O-N 3.26Å; R149-L152 PolarHBondContact O-N 2.78Å; R150-L152 PolarHBondContact O-N 2.91Å; L152-V156 WeakPolarHBondContact O-CG1 3.21Å; L152-V156 PolarHBondContact O-N 2.97Å
153	K	98.6	Very high	95.7	Very high	51 Å²	51	26.4 Å²	26.4	22%	0.222	13%	0.13	C	C	.	.	H	α-helix	trans	-60.5	-46.4	173.5	-163.5	169.1	-177.5	159.6	0	111.5	V79 E80 R149 R150 A151 N157	V79-K153 HydrophobicContact CB-CB 3.95Å; V79-K153 HydrophobicContact CB-CG 4.2Å; V79-K153 HydrophobicContact CG2-CB 4.14Å; V79-K153 HydrophobicContact CG2-CG 4.31Å; E80-K153 IonicContact OE1-NZ 3.7Å; E80-K153 PolarHBondContact OE1-NZ 2.85Å; R149-K153 WeakPolarHBondContact O-CB 3.43Å; R149-K153 PolarHBondContact O-N 3.06Å; R150-K153 WeakPolarHBondContact O-CA 3.43Å; R150-K153 VanDerWaalsContact O-CB 3.26Å; R150-K153 WeakPolarHBondContact O-CB 3.29Å; R150-K153 PolarHBondContact O-N 3.35Å; R150-K153 VanDerWaalsContact O-N 3.12Å; A151-K153 VanDerWaalsContact C-N 3.34Å; K153-N157 WeakPolarHBondContact O-CB 3.46Å; K153-N157 PolarHBondContact O-N 3.48Å; K153-N157 VanDerWaalsContact O-N 3.1Å; K153-N157 PolarHBondContact O-ND2 2.86Å
154	R	98.5	Very high	96.1	Very high	29 Å²	29	22.5 Å²	22.5	11%	0.109	11%	0.112	C	C	.	.	H	α-helix	trans	-66.8	-46.7	177.6	-62.9	-169.4	-43.3	-95.8	-1.6	111.8	R150 A151 V156 N157 L158 E315 L319 D322	R150-R154 WeakPolarHBondContact O-CG 3.44Å; R150-R154 PolarHBondContact O-N 2.71Å; A151-R154 PolarHBondContact O-N 2.88Å; R154-V156 PolarHBondContact O-N 3.47Å; R154-N157 PolarHBondContact O-N 3.31Å; R154-L158 WeakPolarHBondContact O-CG 3.43Å; R154-L158 PolarHBondContact O-N 3.28Å; R154-E315 WeakPolarHBondContact CD-OE2 3.44Å; R154-E315 IonicContact CZ-OE1 3.08Å; R154-E315 IonicContact CZ-OE2 3.95Å; R154-E315 IonicContact NE-OE2 2.66Å; R154-E315 IonicContact NH1-OE1 3.73Å; R154-E315 PolarHBondContact NH1-OE1 2.99Å; R154-E315 IonicContact NH1-OE2 3.53Å; R154-E315 PolarHBondContact NH1-OE2 2.73Å; R154-L319 HydrophobicContact CB-CD1 3.82Å; R154-L319 HydrophobicContact CG-CB 4.47Å; R154-L319 HydrophobicContact CG-CD1 4.08Å; R154-D322 IonicContact CZ-OD2 2.71Å; R154-D322 IonicContact NE-OD2 3.49Å; R154-D322 PolarHBondContact NE-OD2 2.76Å; R154-D322 IonicContact NH2-OD1 3.49Å; R154-D322 IonicContact NH2-OD2 2.68Å; R154-D322 PolarHBondContact NH2-OD2 3.5Å
155	F	98.8	Very high	96.5	Very high	2 Å²	2	20 Å²	20	1%	0.009	10%	0.102	C	C	.	.	H	α-helix	trans	-50	-55.8	172.9	167.9	-90.3	0	0	0	111.7	F113 F116 Q117 L120 P130 L132 A151 N157 L158 V159	F113-F155 HydrophobicContact CD1-CD1 4.02Å; F113-F155 HydrophobicContact CD1-CE1 4.13Å; F116-F155 AromaticContact CD1-CE1 3.93Å; F116-F155 HydrophobicContact CD1-CE1 3.93Å; F116-F155 HydrophobicContact CD1-CZ 4.33Å; F116-F155 HydrophobicContact CE1-CE1 4.11Å; Q117-F155 HydrophobicContact CB-CE2 4.2Å; Q117-F155 HydrophobicContact CB-CZ 4.02Å; Q117-F155 HydrophobicContact CG-CE2 4.01Å; Q117-F155 HydrophobicContact CG-CZ 4.32Å; L120-F155 HydrophobicContact CD1-CZ 4.29Å; P130-F155 HydrophobicContact CB-CD2 3.97Å; P130-F155 HydrophobicContact CG-CD2 4.42Å; P130-F155 WeakPolarHBondContact O-CE2 3.36Å; L132-F155 HydrophobicContact CD2-CB 4.3Å; L132-F155 HydrophobicContact CD2-CD1 3.81Å; L132-F155 HydrophobicContact CD2-CD2 3.59Å; L132-F155 HydrophobicContact CD2-CE1 4.01Å; L132-F155 HydrophobicContact CD2-CE2 3.81Å; L132-F155 HydrophobicContact CD2-CG 3.62Å; L132-F155 HydrophobicContact CD2-CZ 4.02Å; L132-F155 HydrophobicContact CG-CD2 4.23Å; L132-F155 HydrophobicContact CG-CE2 4.19Å; A151-F155 WeakPolarHBondContact O-CB 3.44Å; A151-F155 PolarHBondContact O-N 3.38Å; F155-N157 PolarHBondContact O-N 3.13Å; F155-L158 PolarHBondContact O-N 2.94Å; F155-V159 HydrophobicContact CE1-CG2 4.28Å; F155-V159 HydrophobicContact CE2-CG2 4.2Å; F155-V159 HydrophobicContact CZ-CG2 4.04Å; F155-V159 WeakPolarHBondContact O-CG2 3.46Å; F155-V159 PolarHBondContact O-N 3.03Å
156	V	98.7	Very high	96.9	Very high	0 Å²	0	18.7 Å²	18.7	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-71.3	-29.4	-173.9	73.9	0	0	0	0	112.7	V77 V79 F113 L152 R154 A160 F174 L175	V77-V156 HydrophobicContact CB-CG1 3.9Å; V77-V156 HydrophobicContact CG1-CG1 3.57Å; V77-V156 HydrophobicContact CG1-CG2 4.15Å; V79-V156 HydrophobicContact CG2-CG1 3.65Å; F113-V156 HydrophobicContact CE1-CB 4.37Å; L152-V156 WeakPolarHBondContact O-CG1 3.21Å; L152-V156 PolarHBondContact O-N 2.97Å; R154-V156 PolarHBondContact O-N 3.47Å; V156-A160 WeakPolarHBondContact O-CB 3.38Å; V156-A160 PolarHBondContact O-N 3.43Å; V156-F174 HydrophobicContact CG2-CD1 4.5Å; V156-F174 HydrophobicContact CG2-CE1 4.24Å; V156-L175 HydrophobicContact CG2-CD2 3.96Å
157	N	98.6	Very high	97	Very high	12 Å²	12	20.9 Å²	20.9	6%	0.064	11%	0.105	C	C	.	.	H	α-helix	trans	-72.2	-36.8	172.2	-81.1	-92.1	0	0	0	112.5	V77 K153 R154 F155 V159 R161	V77-N157 PolarHBondContact N-OD1 3.36Å; V77-N157 PolarHBondContact O-ND2 3.46Å; K153-N157 WeakPolarHBondContact O-CB 3.46Å; K153-N157 PolarHBondContact O-N 3.48Å; K153-N157 VanDerWaalsContact O-N 3.1Å; K153-N157 PolarHBondContact O-ND2 2.86Å; R154-N157 PolarHBondContact O-N 3.31Å; F155-N157 PolarHBondContact O-N 3.13Å; N157-V159 VanDerWaalsContact C-N 3.34Å; N157-R161 VanDerWaalsContact O-CB 3.25Å; N157-R161 WeakPolarHBondContact O-CB 3.4Å; N157-R161 WeakPolarHBondContact O-CD 3.39Å; N157-R161 WeakPolarHBondContact O-CG 3.26Å; N157-R161 PolarHBondContact O-N 3Å; N157-R161 PolarHBondContact OD1-NH2 3.19Å
158	L	98.7	Very high	97.1	Very high	12 Å²	12	19.4 Å²	19.4	6%	0.063	9%	0.09	C	C	.	.	H	α-helix	trans	-63.2	-43	172.3	-72.6	176.5	0	0	0	110.8	P130 R154 F155 H162 L319 D322 L323	P130-L158 HydrophobicContact CB-CD1 4.19Å; P130-L158 HydrophobicContact CG-CB 3.74Å; P130-L158 HydrophobicContact CG-CD1 4.01Å; R154-L158 WeakPolarHBondContact O-CG 3.43Å; R154-L158 PolarHBondContact O-N 3.28Å; F155-L158 PolarHBondContact O-N 2.94Å; L158-H162 PolarHBondContact O-N 3.49Å; L158-H162 VanDerWaalsContact O-N 3.15Å; L158-L319 HydrophobicContact CD1-CD1 4.25Å; L158-L319 HydrophobicContact CD2-CD1 3.81Å; L158-L319 HydrophobicContact CD2-CG 4.31Å; L158-L319 HydrophobicContact CG-CD1 3.73Å; L158-D322 HydrophobicContact CD1-CB 3.84Å; L158-L323 HydrophobicContact CD1-CB 4.21Å; L158-L323 HydrophobicContact CD2-CB 4.01Å; L158-L323 HydrophobicContact CD2-CD1 4.43Å
159	V	98.7	Very high	97.1	Very high	0 Å²	0	21.5 Å²	21.5	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-65.9	-51.3	177	177	0	0	0	0	111.5	F116 L120 P130 F155 N157 R161 H162 F165 L171	F116-V159 HydrophobicContact CE1-CG1 4.21Å; F116-V159 HydrophobicContact CZ-CG1 3.86Å; L120-V159 HydrophobicContact CD1-CG1 3.74Å; L120-V159 HydrophobicContact CD1-CG2 3.89Å; L120-V159 HydrophobicContact CD2-CG1 4.38Å; P130-V159 HydrophobicContact CG-CG2 4.21Å; F155-V159 HydrophobicContact CE1-CG2 4.28Å; F155-V159 HydrophobicContact CE2-CG2 4.2Å; F155-V159 HydrophobicContact CZ-CG2 4.04Å; F155-V159 WeakPolarHBondContact O-CG2 3.46Å; F155-V159 PolarHBondContact O-N 3.03Å; N157-V159 VanDerWaalsContact C-N 3.34Å; V159-R161 PolarHBondContact O-N 3.36Å; V159-R161 VanDerWaalsContact O-N 3.09Å; V159-H162 WeakPolarHBondContact O-CB 3.28Å; V159-H162 PolarHBondContact O-N 3.13Å; V159-F165 HydrophobicContact CB-CD2 4.34Å; V159-F165 HydrophobicContact CG1-CB 3.81Å; V159-F165 HydrophobicContact CG1-CD2 3.88Å; V159-F165 HydrophobicContact CG1-CG 4.22Å; V159-F165 HydrophobicContact CG2-CD2 4.42Å; V159-F165 WeakPolarHBondContact O-CB 3.46Å; V159-L171 HydrophobicContact CG1-CD1 4.05Å
160	A	98.5	Very high	97.1	Very high	0 Å²	0	20.5 Å²	20.5	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-66.3	-14.3	-176.7	0	0	0	0	0	114.4	D75 V77 V156 S166 L171 L175	D75-A160 HydrophobicContact CB-CB 4Å; V77-A160 HydrophobicContact CG2-CB 4Å; V156-A160 WeakPolarHBondContact O-CB 3.38Å; V156-A160 PolarHBondContact O-N 3.43Å; A160-S166 WeakPolarHBondContact O-CB 3.39Å; A160-L171 HydrophobicContact CB-CD1 4.38Å; A160-L171 HydrophobicContact CB-CD2 4.12Å; A160-L175 HydrophobicContact CB-CD1 4.47Å
161	R	98.1	Very high	97.1	Very high	26 Å²	26	18.8 Å²	18.8	10%	0.098	10%	0.095	C	C	.	.	H	α-helix	trans	-104.7	-5.7	176.3	-63	176.3	172.9	152	2.2	113.7	L71 L72 D75 T76 N157 V159	L71-R161 VanDerWaalsContact O-CB 3.29Å; L71-R161 WeakPolarHBondContact O-CB 3.37Å; L71-R161 WeakPolarHBondContact O-CD 3.11Å; L71-R161 WeakPolarHBondContact O-CG 3.43Å; L72-R161 PolarHBondContact O-NE 3.48Å; D75-R161 VanDerWaalsContact O-CZ 3.31Å; D75-R161 PolarHBondContact O-NE 3.28Å; D75-R161 PolarHBondContact O-NH2 3.05Å; T76-R161 PolarHBondContact OG1-NH2 3.41Å; N157-R161 VanDerWaalsContact O-CB 3.25Å; N157-R161 WeakPolarHBondContact O-CB 3.4Å; N157-R161 WeakPolarHBondContact O-CD 3.39Å; N157-R161 WeakPolarHBondContact O-CG 3.26Å; N157-R161 PolarHBondContact O-N 3Å; N157-R161 PolarHBondContact OD1-NH2 3.19Å; V159-R161 PolarHBondContact O-N 3.36Å; V159-R161 VanDerWaalsContact O-N 3.09Å
162	H	98	Very high	97.1	Very high	8 Å²	8	23.6 Å²	23.6	4%	0.037	11%	0.114	C	C	.	.	S	Bend	trans	-70.4	131.8	176.8	-174.7	-95.9	0	0	0	110.6	L158 V159 L164 F165 S166 E400 L403	L158-H162 PolarHBondContact O-N 3.49Å; L158-H162 VanDerWaalsContact O-N 3.15Å; V159-H162 WeakPolarHBondContact O-CB 3.28Å; V159-H162 PolarHBondContact O-N 3.13Å; H162-L164 PolarHBondContact ND1-N 3.14Å; H162-L164 PolarHBondContact O-N 2.92Å; H162-F165 HydrophobicContact CB-CB 4.07Å; H162-F165 HydrophobicContact CB-CD2 3.32Å; H162-F165 HydrophobicContact CB-CE2 3.9Å; H162-F165 HydrophobicContact CB-CG 3.84Å; H162-F165 AromaticContact CE1-CE1 3.94Å; H162-F165 AromaticContact CE1-CZ 3.89Å; H162-F165 AromaticContact CG-CD2 3.42Å; H162-F165 VanDerWaalsContact CG-CD2 3.42Å; H162-F165 AromaticContact CG-CE2 3.56Å; H162-F165 AromaticContact CG-CG 3.85Å; H162-F165 AromaticContact ND1-CD1 3.57Å; H162-F165 AromaticContact ND1-CD2 3.49Å; H162-F165 WeakPolarHBondContact ND1-CD2 3.32Å; H162-F165 AromaticContact ND1-CE1 3.67Å; H162-F165 AromaticContact ND1-CE2 3.61Å; H162-F165 AromaticContact ND1-CG 3.47Å; H162-F165 WeakPolarHBondContact ND1-CG 3.48Å; H162-F165 AromaticContact ND1-CZ 3.71Å; H162-F165 PolarHBondContact O-N 3.17Å; H162-S166 WeakPolarHBondContact O-CB 3.49Å; H162-S166 PolarHBondContact O-N 3.46Å; H162-S166 PolarHBondContact O-OG 3.48Å; H162-E400 IonicContact CE1-OE1 3.56Å; H162-E400 IonicContact CE1-OE2 2.74Å; H162-E400 IonicContact NE2-OE1 3.46Å; H162-E400 PolarHBondContact NE2-OE1 2.89Å; H162-E400 IonicContact NE2-OE2 2.88Å; H162-E400 PolarHBondContact NE2-OE2 2.71Å; H162-E400 VanDerWaalsContact NE2-OE2 3.08Å; H162-L403 WeakPolarHBondContact CD2-CD2 3.25Å; H162-L403 WeakPolarHBondContact NE2-CD2 3.27Å
163	P	95.7	Very high	97	Very high	12 Å²	12	25.6 Å²	25.6	8%	0.078	12%	0.124	C	C	.	.	T	Hydrogen-bonded Turn	trans	-53.6	-30.3	-171.4	-31.5	36.9	0	0	0	116.7	L71 R74 L403	L71-P163 HydrophobicContact CD2-CG 4Å; R74-P163 PolarHBondContact NH1-O 3.48Å; R74-P163 VanDerWaalsContact NH1-O 3.13Å; P163-L403 HydrophobicContact CG-CD1 4.03Å; P163-L403 HydrophobicContact CG-CD2 4.29Å
164	L	94.1	Very high	97	Very high	38 Å²	38	23.2 Å²	23.2	20%	0.199	11%	0.114	C	C	.	.	T	Hydrogen-bonded Turn	trans	-97.6	-36.5	179.8	-58.3	-179.2	0	0	0	113.6	M54 F124 R127 H162	M54-L164 HydrophobicContact CE-CD2 3.55Å; F124-L164 HydrophobicContact CE1-CB 4.47Å; R127-L164 HydrophobicContact CG-CD1 4.26Å; R127-L164 VanDerWaalsContact NE-CD1 3.29Å; H162-L164 PolarHBondContact ND1-N 3.14Å; H162-L164 PolarHBondContact O-N 2.92Å
165	F	96.8	Very high	97	Very high	1 Å²	1	21.8 Å²	21.8	0%	0.004	11%	0.108	C	C	.	.	G	3₁₀ helix	trans	-76.7	-28.8	-175.5	-47.6	-30.6	0	0	0	111.2	L120 F124 R127 V129 V159 H162 E167 D168 L171	L120-F165 HydrophobicContact CD2-CB 4.44Å; L120-F165 HydrophobicContact CD2-CD1 4.27Å; L120-F165 HydrophobicContact CD2-CG 4.23Å; F124-F165 HydrophobicContact CB-CD1 4.46Å; F124-F165 HydrophobicContact CB-CE1 3.62Å; F124-F165 HydrophobicContact CB-CZ 4.4Å; F124-F165 HydrophobicContact CD1-CD1 4.42Å; F124-F165 HydrophobicContact CD1-CE1 4.2Å; F124-F165 AromaticContact CD2-CD1 3.68Å; F124-F165 HydrophobicContact CD2-CD1 3.68Å; F124-F165 AromaticContact CD2-CE1 3.69Å; F124-F165 HydrophobicContact CD2-CE1 3.69Å; F124-F165 AromaticContact CE2-CD1 3.92Å; F124-F165 HydrophobicContact CE2-CD1 3.92Å; F124-F165 HydrophobicContact CE2-CE1 4.37Å; F124-F165 AromaticContact CG-CD1 3.96Å; F124-F165 HydrophobicContact CG-CD1 3.96Å; F124-F165 AromaticContact CG-CE1 3.58Å; F124-F165 HydrophobicContact CG-CE1 3.58Å; F124-F165 HydrophobicContact CZ-CD1 4.39Å; R127-F165 HydrophobicContact CB-CE1 3.76Å; R127-F165 HydrophobicContact CB-CZ 3.55Å; R127-F165 HydrophobicContact CG-CE1 4.15Å; R127-F165 HydrophobicContact CG-CZ 4.42Å; V129-F165 HydrophobicContact CG2-CE1 4.47Å; V129-F165 HydrophobicContact CG2-CE2 4.29Å; V129-F165 HydrophobicContact CG2-CZ 3.74Å; V159-F165 HydrophobicContact CB-CD2 4.34Å; V159-F165 HydrophobicContact CG1-CB 3.81Å; V159-F165 HydrophobicContact CG1-CD2 3.88Å; V159-F165 HydrophobicContact CG1-CG 4.22Å; V159-F165 HydrophobicContact CG2-CD2 4.42Å; V159-F165 WeakPolarHBondContact O-CB 3.46Å; H162-F165 HydrophobicContact CB-CB 4.07Å; H162-F165 HydrophobicContact CB-CD2 3.32Å; H162-F165 HydrophobicContact CB-CE2 3.9Å; H162-F165 HydrophobicContact CB-CG 3.84Å; H162-F165 AromaticContact CE1-CE1 3.94Å; H162-F165 AromaticContact CE1-CZ 3.89Å; H162-F165 AromaticContact CG-CD2 3.42Å; H162-F165 VanDerWaalsContact CG-CD2 3.42Å; H162-F165 AromaticContact CG-CE2 3.56Å; H162-F165 AromaticContact CG-CG 3.85Å; H162-F165 AromaticContact ND1-CD1 3.57Å; H162-F165 AromaticContact ND1-CD2 3.49Å; H162-F165 WeakPolarHBondContact ND1-CD2 3.32Å; H162-F165 AromaticContact ND1-CE1 3.67Å; H162-F165 AromaticContact ND1-CE2 3.61Å; H162-F165 AromaticContact ND1-CG 3.47Å; H162-F165 WeakPolarHBondContact ND1-CG 3.48Å; H162-F165 AromaticContact ND1-CZ 3.71Å; H162-F165 PolarHBondContact O-N 3.17Å; F165-E167 PolarHBondContact O-N 3.28Å; F165-D168 PolarHBondContact O-N 3.05Å; F165-D168 VanDerWaalsContact O-N 3.13Å; F165-L171 WeakPolarHBondContact O-CB 3.14Å; F165-L171 VanDerWaalsContact O-CD2 3.27Å; F165-L171 WeakPolarHBondContact O-CD2 3.45Å
166	S	96.1	Very high	96.9	Very high	1 Å²	1	24 Å²	24	1%	0.007	12%	0.124	C	C	.	.	G	3₁₀ helix	trans	-63.1	-24.9	179.7	71.8	0	0	0	0	113.7	R74 R101 A160 H162	R74-S166 PolarHBondContact NH1-OG 3.09Å; R101-S166 PolarHBondContact NH1-O 3.05Å; R101-S166 VanDerWaalsContact NH1-O 3.11Å; A160-S166 WeakPolarHBondContact O-CB 3.39Å; H162-S166 WeakPolarHBondContact O-CB 3.49Å; H162-S166 PolarHBondContact O-N 3.46Å; H162-S166 PolarHBondContact O-OG 3.48Å
167	E	93.3	Very high	96.8	Very high	96 Å²	96	27 Å²	27	45%	0.449	14%	0.137	S	C	.	.	G	3₁₀ helix	trans	-99.7	-2.4	179.1	-49.4	-42.8	115.8	0	0	112.9	R74 R101 F165	R74-E167 IonicContact NH1-OE1 3.51Å; R101-E167 IonicContact CZ-OE1 3.72Å; R101-E167 IonicContact CZ-OE2 2.72Å; R101-E167 IonicContact NH1-OE1 2.8Å; R101-E167 PolarHBondContact NH1-OE1 3.18Å; R101-E167 IonicContact NH1-OE2 3.46Å; R101-E167 IonicContact NH2-OE1 2.71Å; R101-E167 PolarHBondContact NH2-OE1 3.33Å; R101-E167 IonicContact NH2-OE2 3.26Å; R101-E167 PolarHBondContact NH2-OE2 3.01Å; F165-E167 PolarHBondContact O-N 3.28Å
168	D	94.6	Very high	96.6	Very high	22 Å²	22	31.7 Å²	31.7	12%	0.118	17%	0.171	C	C	.	.			trans	-83	139.1	-176.1	-161.7	-92.4	0	0	0	112.9	K123 F124 F165 V170 L171 K172	K123-D168 VanDerWaalsContact CE-OD2 3.27Å; K123-D168 WeakPolarHBondContact CE-OD2 3.41Å; K123-D168 IonicContact NZ-OD1 2.68Å; K123-D168 PolarHBondContact NZ-OD1 3.41Å; K123-D168 IonicContact NZ-OD2 2.69Å; K123-D168 PolarHBondContact NZ-OD2 3.35Å; F124-D168 HydrophobicContact CE2-CB 4.24Å; F124-D168 HydrophobicContact CZ-CB 4.1Å; F165-D168 PolarHBondContact O-N 3.05Å; F165-D168 VanDerWaalsContact O-N 3.13Å; D168-V170 PolarHBondContact O-N 2.82Å; D168-V170 VanDerWaalsContact OD1-CB 3.29Å; D168-V170 WeakPolarHBondContact OD1-CB 3.32Å; D168-V170 VanDerWaalsContact OD1-CG2 3.26Å; D168-V170 WeakPolarHBondContact OD1-CG2 3.47Å; D168-V170 PolarHBondContact OD1-N 3.35Å; D168-L171 PolarHBondContact O-N 3.38Å; D168-K172 PolarHBondContact O-N 3.11Å
169	V	94.2	Very high	96.2	Very high	69 Å²	69	32.3 Å²	32.3	42%	0.418	18%	0.181	S	C	.	.	H	α-helix	trans	-57.3	-32.1	177.1	60.5	0	0	0	0	113	K172 L173 S189	V169-K172 PolarHBondContact O-N 2.74Å; V169-L173 HydrophobicContact CG2-CD1 4.07Å; V169-L173 HydrophobicContact CG2-CG 4.25Å; V169-L173 WeakPolarHBondContact O-CB 3.42Å; V169-L173 VanDerWaalsContact O-CG 3.3Å; V169-L173 WeakPolarHBondContact O-CG 3.43Å; V169-L173 PolarHBondContact O-N 2.76Å; V169-S189 WeakPolarHBondContact CG1-OG 3.48Å
170	V	95.4	Very high	95.7	Very high	1 Å²	1	38.4 Å²	38.4	1%	0.006	22%	0.223	C	C	.	.	H	α-helix	trans	-67.9	-38.3	-179.5	-178	0	0	0	0	111	F116 M119 K123 D168 F174 L186	F116-V170 HydrophobicContact CD2-CG1 3.87Å; F116-V170 HydrophobicContact CE2-CG1 3.93Å; M119-V170 HydrophobicContact CB-CG1 4.05Å; K123-V170 HydrophobicContact CD-CG2 4.4Å; D168-V170 PolarHBondContact O-N 2.82Å; D168-V170 VanDerWaalsContact OD1-CB 3.29Å; D168-V170 WeakPolarHBondContact OD1-CB 3.32Å; D168-V170 VanDerWaalsContact OD1-CG2 3.26Å; D168-V170 WeakPolarHBondContact OD1-CG2 3.47Å; D168-V170 PolarHBondContact OD1-N 3.35Å; V170-F174 WeakPolarHBondContact O-CB 3.36Å; V170-F174 PolarHBondContact O-N 2.96Å; V170-L186 HydrophobicContact CG1-CD2 3.58Å; V170-L186 VanDerWaalsContact O-CD2 3.32Å; V170-L186 WeakPolarHBondContact O-CD2 3.08Å
171	L	97.5	Very high	95.4	Very high	2 Å²	2	41.5 Å²	41.5	1%	0.01	24%	0.24	C	C	.	.	H	α-helix	trans	-66.2	-46.2	171.5	174.2	71.8	0	0	0	111.1	F116 V159 A160 F165 D168 L173 F174 L175	F116-L171 HydrophobicContact CE1-CD1 4.15Å; F116-L171 HydrophobicContact CE2-CB 4.44Å; F116-L171 HydrophobicContact CZ-CB 4.14Å; F116-L171 HydrophobicContact CZ-CD1 3.6Å; F116-L171 HydrophobicContact CZ-CG 4.49Å; V159-L171 HydrophobicContact CG1-CD1 4.05Å; A160-L171 HydrophobicContact CB-CD1 4.38Å; A160-L171 HydrophobicContact CB-CD2 4.12Å; F165-L171 WeakPolarHBondContact O-CB 3.14Å; F165-L171 VanDerWaalsContact O-CD2 3.27Å; F165-L171 WeakPolarHBondContact O-CD2 3.45Å; D168-L171 PolarHBondContact O-N 3.38Å; L171-L173 VanDerWaalsContact C-N 3.33Å; L171-L173 PolarHBondContact O-N 3.34Å; L171-F174 PolarHBondContact O-N 3.27Å; L171-F174 VanDerWaalsContact O-N 3.11Å; L171-L175 HydrophobicContact CD1-CD1 3.62Å; L171-L175 HydrophobicContact CD1-CG 3.97Å; L171-L175 HydrophobicContact CD2-CD1 4.44Å; L171-L175 HydrophobicContact CG-CD1 3.95Å; L171-L175 HydrophobicContact CG-CG 4.46Å; L171-L175 PolarHBondContact O-N 3.32Å
172	K	96.9	Very high	95.3	Very high	114 Å²	114	40.4 Å²	40.4	50%	0.496	24%	0.236	S	C	.	.	H	α-helix	trans	-57.7	-46.8	179.6	-175.8	179.7	177.9	-176	0	110.9	F102 D168 V169 F174 L175 S176	F102-K172 HydrophobicContact CD1-CG 4.26Å; F102-K172 HydrophobicContact CE1-CB 4.3Å; F102-K172 HydrophobicContact CE1-CD 4.27Å; F102-K172 HydrophobicContact CE1-CG 3.87Å; F102-K172 HydrophobicContact CZ-CB 4.13Å; F102-K172 HydrophobicContact CZ-CG 4.21Å; D168-K172 PolarHBondContact O-N 3.11Å; V169-K172 PolarHBondContact O-N 2.74Å; K172-F174 PolarHBondContact O-N 3.13Å; K172-L175 PolarHBondContact O-N 3.43Å; K172-S176 WeakPolarHBondContact O-CB 3.49Å; K172-S176 PolarHBondContact O-N 2.9Å; K172-S176 PolarHBondContact O-OG 3.2Å
173	L	97.1	Very high	95.2	Very high	42 Å²	42	41.6 Å²	41.6	22%	0.22	24%	0.242	C	C	.	.	H	α-helix	trans	-58.3	-47.1	173.3	-72.6	170	0	0	0	111.4	R108 V169 L171 L175 F177 L186	R108-L173 PolarHBondContact NH2-O 2.94Å; V169-L173 HydrophobicContact CG2-CD1 4.07Å; V169-L173 HydrophobicContact CG2-CG 4.25Å; V169-L173 WeakPolarHBondContact O-CB 3.42Å; V169-L173 VanDerWaalsContact O-CG 3.3Å; V169-L173 WeakPolarHBondContact O-CG 3.43Å; V169-L173 PolarHBondContact O-N 2.76Å; L171-L173 VanDerWaalsContact C-N 3.33Å; L171-L173 PolarHBondContact O-N 3.34Å; L173-L175 VanDerWaalsContact C-N 3.29Å; L173-L175 PolarHBondContact O-N 3.12Å; L173-F177 WeakPolarHBondContact O-CB 3.15Å; L173-F177 PolarHBondContact O-N 2.61Å; L173-L186 HydrophobicContact CB-CD2 4.2Å
174	F	98.3	Very high	95.2	Very high	0 Å²	0	44.5 Å²	44.5	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-59.7	-36.4	178.3	-174.7	-98.8	0	0	0	113.1	R108 D112 F113 F116 V156 V170 L171 K172 L186	R108-F174 HydrophobicContact CB-CZ 4.4Å; R108-F174 HydrophobicContact CG-CE1 4.5Å; R108-F174 HydrophobicContact CG-CE2 4.14Å; R108-F174 HydrophobicContact CG-CZ 3.89Å; R108-F174 VanDerWaalsContact CZ-O 3.26Å; R108-F174 PolarHBondContact NE-O 3.25Å; R108-F174 PolarHBondContact NH2-O 2.99Å; D112-F174 HydrophobicContact CB-CE2 4.3Å; F113-F174 HydrophobicContact CD1-CE1 4.05Å; F113-F174 AromaticContact CD1-CZ 3.57Å; F113-F174 HydrophobicContact CD1-CZ 3.57Å; F113-F174 AromaticContact CD2-CZ 3.98Å; F113-F174 HydrophobicContact CD2-CZ 3.98Å; F113-F174 AromaticContact CE1-CE1 3.83Å; F113-F174 HydrophobicContact CE1-CE1 3.83Å; F113-F174 AromaticContact CE1-CZ 3.64Å; F113-F174 HydrophobicContact CE1-CZ 3.64Å; F113-F174 HydrophobicContact CE2-CZ 4.03Å; F113-F174 HydrophobicContact CG-CE2 4.43Å; F113-F174 AromaticContact CG-CZ 3.76Å; F113-F174 HydrophobicContact CG-CZ 3.76Å; F113-F174 HydrophobicContact CZ-CE1 4.25Å; F113-F174 AromaticContact CZ-CZ 3.88Å; F113-F174 HydrophobicContact CZ-CZ 3.88Å; F116-F174 HydrophobicContact CB-CD2 3.64Å; F116-F174 HydrophobicContact CB-CE2 3.9Å; F116-F174 HydrophobicContact CB-CG 4.23Å; F116-F174 HydrophobicContact CD1-CB 4.15Å; F116-F174 AromaticContact CD1-CD1 3.59Å; F116-F174 HydrophobicContact CD1-CD1 3.59Å; F116-F174 AromaticContact CD1-CD2 3.73Å; F116-F174 HydrophobicContact CD1-CD2 3.73Å; F116-F174 AromaticContact CD1-CE1 3.89Å; F116-F174 HydrophobicContact CD1-CE1 3.89Å; F116-F174 HydrophobicContact CD1-CE2 4.01Å; F116-F174 AromaticContact CD1-CG 3.51Å; F116-F174 HydrophobicContact CD1-CG 3.51Å; F116-F174 HydrophobicContact CD1-CZ 4.09Å; F116-F174 HydrophobicContact CD2-CB 3.96Å; F116-F174 HydrophobicContact CD2-CD2 4.32Å; F116-F174 HydrophobicContact CD2-CG 4.14Å; F116-F174 HydrophobicContact CE1-CB 4.16Å; F116-F174 AromaticContact CE1-CD1 3.63Å; F116-F174 HydrophobicContact CE1-CD1 3.63Å; F116-F174 HydrophobicContact CE1-CD2 4.48Å; F116-F174 HydrophobicContact CE1-CE1 4.17Å; F116-F174 AromaticContact CE1-CG 3.82Å; F116-F174 HydrophobicContact CE1-CG 3.82Å; F116-F174 HydrophobicContact CE2-CB 3.98Å; F116-F174 HydrophobicContact CE2-CG 4.4Å; F116-F174 HydrophobicContact CG-CB 4.06Å; F116-F174 HydrophobicContact CG-CD1 4.27Å; F116-F174 AromaticContact CG-CD2 3.64Å; F116-F174 HydrophobicContact CG-CD2 3.64Å; F116-F174 HydrophobicContact CG-CE2 4.17Å; F116-F174 AromaticContact CG-CG 3.7Å; F116-F174 HydrophobicContact CG-CG 3.7Å; F116-F174 HydrophobicContact CZ-CB 4.08Å; F116-F174 HydrophobicContact CZ-CD1 4.32Å; F116-F174 HydrophobicContact CZ-CG 4.25Å; V156-F174 HydrophobicContact CG2-CD1 4.5Å; V156-F174 HydrophobicContact CG2-CE1 4.24Å; V170-F174 WeakPolarHBondContact O-CB 3.36Å; V170-F174 PolarHBondContact O-N 2.96Å; L171-F174 PolarHBondContact O-N 3.27Å; L171-F174 VanDerWaalsContact O-N 3.11Å; K172-F174 PolarHBondContact O-N 3.13Å; F174-L186 HydrophobicContact CB-CD2 4.16Å; F174-L186 HydrophobicContact CD2-CD1 4.19Å
175	L	98.3	Very high	95.2	Very high	0 Å²	0	46.3 Å²	46.3	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-93	-19.7	-177.4	-68.7	178.9	0	0	0	115.4	V77 V97 F102 S104 V106 V156 A160 L171 K172 L173	V77-L175 HydrophobicContact CG1-CD2 4.01Å; V77-L175 HydrophobicContact CG2-CD1 4.09Å; V77-L175 HydrophobicContact CG2-CD2 4.37Å; V97-L175 HydrophobicContact CG1-CD2 3.6Å; F102-L175 HydrophobicContact CD2-CB 3.89Å; F102-L175 HydrophobicContact CD2-CD1 3.86Å; F102-L175 HydrophobicContact CE2-CB 4.4Å; F102-L175 HydrophobicContact CE2-CD1 3.9Å; S104-L175 WeakPolarHBondContact CB-O 3.5Å; S104-L175 PolarHBondContact OG-O 3.01Å; V106-L175 WeakPolarHBondContact CG2-O 3.42Å; V156-L175 HydrophobicContact CG2-CD2 3.96Å; A160-L175 HydrophobicContact CB-CD1 4.47Å; L171-L175 HydrophobicContact CD1-CD1 3.62Å; L171-L175 HydrophobicContact CD1-CG 3.97Å; L171-L175 HydrophobicContact CD2-CD1 4.44Å; L171-L175 HydrophobicContact CG-CD1 3.95Å; L171-L175 HydrophobicContact CG-CG 4.46Å; L171-L175 PolarHBondContact O-N 3.32Å; K172-L175 PolarHBondContact O-N 3.43Å; L173-L175 VanDerWaalsContact C-N 3.29Å; L173-L175 PolarHBondContact O-N 3.12Å
176	S	97.3	Very high	95.1	Very high	49 Å²	49	46.2 Å²	46.2	34%	0.343	26%	0.262	S	S	.	.	H	α-helix	trans	-122.9	-8.7	-174.2	89.5	0	0	0	0	116.2	K172 S178	K172-S176 WeakPolarHBondContact O-CB 3.49Å; K172-S176 PolarHBondContact O-N 2.9Å; K172-S176 PolarHBondContact O-OG 3.2Å; S176-S178 PolarHBondContact O-N 3.2Å
177	F	97	Very high	95	Very high	61 Å²	61	49.2 Å²	49.2	27%	0.268	28%	0.275	S	S	.	.			trans	-83.9	112	179.4	-176.2	-108.1	0	0	0	112	R108 L173 G179 V182 K185	R108-F177 PolarHBondContact NH1-O 3.23Å; R108-F177 VanDerWaalsContact NH1-O 3.07Å; R108-F177 PolarHBondContact NH2-O 3.06Å; L173-F177 WeakPolarHBondContact O-CB 3.15Å; L173-F177 PolarHBondContact O-N 2.61Å; F177-G179 WeakPolarHBondContact CD1-O 3.41Å; F177-G179 VanDerWaalsContact CE1-CA 3.44Å; F177-G179 VanDerWaalsContact CE1-O 3.27Å; F177-G179 WeakPolarHBondContact CE1-O 3.42Å; F177-V182 HydrophobicContact CD1-CB 3.98Å; F177-V182 HydrophobicContact CD1-CG2 4.22Å; F177-V182 HydrophobicContact CE1-CB 4.49Å; F177-K185 HydrophobicContact CE1-CG 4.23Å; F177-K185 HydrophobicContact CZ-CG 4.12Å
178	S	93.5	Very high	94.9	Very high	111 Å²	111	48.7 Å²	48.7	78%	0.776	27%	0.273	S	S	*	.			trans	-82.4	-10.2	-179.2	52.2	0	0	0	0	114.8	S176	S176-S178 PolarHBondContact O-N 3.2Å
179	G	90.9	Very high	94.6	Very high	26 Å²	26	48.9 Å²	48.9	27%	0.268	28%	0.275	S	S	.	.	S	Bend	trans	-71.6	152.1	-179.9	0	0	0	0	0	113.6	F177 D181	F177-G179 WeakPolarHBondContact CD1-O 3.41Å; F177-G179 VanDerWaalsContact CE1-CA 3.44Å; F177-G179 VanDerWaalsContact CE1-O 3.27Å; F177-G179 WeakPolarHBondContact CE1-O 3.42Å; G179-D181 VanDerWaalsContact C-N 3.31Å; G179-D181 PolarHBondContact O-N 2.99Å
180	S	88.1	Confident	94	Very high	127 Å²	127	45.6 Å²	45.6	89%	0.888	26%	0.256	S	S	*	.	S	Bend	trans	-65.3	-29.6	-178.5	50.4	0	0	0	0	113.9	V182	S180-V182 VanDerWaalsContact C-N 3.27Å; S180-V182 PolarHBondContact O-N 3.4Å
181	D	93.1	Very high	93.2	Very high	66 Å²	66	52.2 Å²	52.2	35%	0.353	29%	0.287	S	S	.	.			trans	-90.6	47.3	-179	-163.7	9.6	0	0	0	113.7	G179 Q183 N184 K185	G179-D181 VanDerWaalsContact C-N 3.31Å; G179-D181 PolarHBondContact O-N 2.99Å; D181-Q183 PolarHBondContact O-N 3.28Å; D181-N184 VanDerWaalsContact CG-ND2 3.27Å; D181-N184 VanDerWaalsContact OD1-CB 3.24Å; D181-N184 WeakPolarHBondContact OD1-CB 3.29Å; D181-N184 PolarHBondContact OD1-N 2.85Å; D181-N184 PolarHBondContact OD1-ND2 3.13Å; D181-N184 WeakPolarHBondContact OD2-CB 3.44Å; D181-N184 PolarHBondContact OD2-ND2 2.62Å; D181-K185 WeakPolarHBondContact O-CG 3.35Å; D181-K185 PolarHBondContact O-N 3.23Å
182	V	95.7	Very high	91.8	Very high	3 Å²	3	57.8 Å²	57.8	2%	0.018	32%	0.324	C	S	.	.	H	α-helix	trans	-60.7	-33.2	174.9	68.2	0	0	0	0	111.4	D112 F177 S180 K185 L186	D112-V182 HydrophobicContact CB-CG1 4.14Å; F177-V182 HydrophobicContact CD1-CB 3.98Å; F177-V182 HydrophobicContact CD1-CG2 4.22Å; F177-V182 HydrophobicContact CE1-CB 4.49Å; S180-V182 VanDerWaalsContact C-N 3.27Å; S180-V182 PolarHBondContact O-N 3.4Å; V182-K185 PolarHBondContact O-N 3.34Å; V182-L186 HydrophobicContact CG2-CD1 4Å; V182-L186 HydrophobicContact CG2-CG 4.22Å; V182-L186 WeakPolarHBondContact O-CG 3.42Å; V182-L186 PolarHBondContact O-N 3.41Å
183	Q	95.8	Very high	90.6	Very high	33 Å²	33	55.1 Å²	55.1	15%	0.154	32%	0.318	C	S	.	.	H	α-helix	trans	-68.5	-39.6	-174.7	-65.7	-165.7	4.5	0	0	113.4	N111 D112 V115 D181 K187	N111-Q183 PolarHBondContact O-NE2 3.15Å; D112-Q183 PolarHBondContact OD1-NE2 2.85Å; V115-Q183 HydrophobicContact CB-CG 4.38Å; V115-Q183 HydrophobicContact CG1-CB 4.34Å; V115-Q183 HydrophobicContact CG2-CB 4.47Å; V115-Q183 HydrophobicContact CG2-CG 4.17Å; D181-Q183 PolarHBondContact O-N 3.28Å; Q183-K187 WeakPolarHBondContact O-CD 3.37Å; Q183-K187 VanDerWaalsContact O-CG 3.3Å; Q183-K187 WeakPolarHBondContact O-CG 3.27Å; Q183-K187 PolarHBondContact O-N 2.96Å
184	N	95.2	Very high	90.1	Very high	72 Å²	72	54.3 Å²	54.3	39%	0.385	32%	0.319	S	S	.	.	H	α-helix	trans	-74	-39.9	175.7	-64.1	-24.9	0	0	0	110.9	D181 L186 K187 E188	D181-N184 VanDerWaalsContact CG-ND2 3.27Å; D181-N184 VanDerWaalsContact OD1-CB 3.24Å; D181-N184 WeakPolarHBondContact OD1-CB 3.29Å; D181-N184 PolarHBondContact OD1-N 2.85Å; D181-N184 PolarHBondContact OD1-ND2 3.13Å; D181-N184 WeakPolarHBondContact OD2-CB 3.44Å; D181-N184 PolarHBondContact OD2-ND2 2.62Å; N184-L186 VanDerWaalsContact C-N 3.29Å; N184-L186 PolarHBondContact O-N 2.93Å; N184-K187 WeakPolarHBondContact O-CA 3.4Å; N184-K187 WeakPolarHBondContact O-CB 3.47Å; N184-K187 PolarHBondContact O-N 2.96Å; N184-E188 VanDerWaalsContact O-CG 3.32Å; N184-E188 WeakPolarHBondContact O-CG 3.42Å; N184-E188 PolarHBondContact O-N 2.87Å
185	K	94.6	Very high	89.8	Confident	76 Å²	76	55.6 Å²	55.6	33%	0.33	33%	0.326	S	S	.	.	H	α-helix	trans	-59.5	-36.4	177	-68.6	-78	160	-90.3	0	113.1	F177 D181 V182 E188 S189	F177-K185 HydrophobicContact CE1-CG 4.23Å; F177-K185 HydrophobicContact CZ-CG 4.12Å; D181-K185 WeakPolarHBondContact O-CG 3.35Å; D181-K185 PolarHBondContact O-N 3.23Å; V182-K185 PolarHBondContact O-N 3.34Å; K185-E188 IonicContact NZ-OE1 2.67Å; K185-E188 PolarHBondContact NZ-OE1 3.44Å; K185-E188 IonicContact NZ-OE2 3.52Å; K185-E188 PolarHBondContact NZ-OE2 3.14Å; K185-S189 VanDerWaalsContact O-CB 3.28Å; K185-S189 WeakPolarHBondContact O-CB 3.44Å; K185-S189 PolarHBondContact O-N 2.93Å; K185-S189 VanDerWaalsContact O-N 3.15Å
186	L	95	Very high	89.6	Confident	0 Å²	0	56.2 Å²	56.2	0%	0	33%	0.329	C	S	.	.	H	α-helix	trans	-65.6	-41.4	171.5	-68.8	166.6	0	0	0	112.5	V115 F116 M119 V170 L173 F174 V182 N184 A190	V115-L186 HydrophobicContact CG1-CB 4.43Å; V115-L186 HydrophobicContact CG1-CD1 4.37Å; F116-L186 HydrophobicContact CB-CD1 4.2Å; F116-L186 HydrophobicContact CD2-CD2 4.29Å; M119-L186 HydrophobicContact CG-CB 4.23Å; V170-L186 HydrophobicContact CG1-CD2 3.58Å; V170-L186 VanDerWaalsContact O-CD2 3.32Å; V170-L186 WeakPolarHBondContact O-CD2 3.08Å; L173-L186 HydrophobicContact CB-CD2 4.2Å; F174-L186 HydrophobicContact CB-CD2 4.16Å; F174-L186 HydrophobicContact CD2-CD1 4.19Å; V182-L186 HydrophobicContact CG2-CD1 4Å; V182-L186 HydrophobicContact CG2-CG 4.22Å; V182-L186 WeakPolarHBondContact O-CG 3.42Å; V182-L186 PolarHBondContact O-N 3.41Å; N184-L186 VanDerWaalsContact C-N 3.29Å; N184-L186 PolarHBondContact O-N 2.93Å; L186-A190 WeakPolarHBondContact O-CB 3.44Å; L186-A190 PolarHBondContact O-N 2.96Å
187	K	93.9	Very high	89.5	Confident	63 Å²	63	54.9 Å²	54.9	27%	0.274	32%	0.317	S	S	.	.	H	α-helix	trans	-69.4	-47.8	-180	-69	166.5	-172.1	170.8	0	112	V115 M119 Q183 N184 S189 A190 Q191	V115-K187 HydrophobicContact CG1-CG 4.23Å; M119-K187 HydrophobicContact CE-CG 4.38Å; M119-K187 HydrophobicContact SD-CB 4.37Å; M119-K187 HydrophobicContact SD-CG 3.96Å; Q183-K187 WeakPolarHBondContact O-CD 3.37Å; Q183-K187 VanDerWaalsContact O-CG 3.3Å; Q183-K187 WeakPolarHBondContact O-CG 3.27Å; Q183-K187 PolarHBondContact O-N 2.96Å; N184-K187 WeakPolarHBondContact O-CA 3.4Å; N184-K187 WeakPolarHBondContact O-CB 3.47Å; N184-K187 PolarHBondContact O-N 2.96Å; K187-S189 VanDerWaalsContact C-N 3.3Å; K187-S189 PolarHBondContact O-N 3.39Å; K187-A190 PolarHBondContact O-N 3.41Å; K187-A190 VanDerWaalsContact O-N 3.1Å; K187-Q191 WeakPolarHBondContact O-CB 3.22Å; K187-Q191 VanDerWaalsContact O-CG 3.27Å; K187-Q191 WeakPolarHBondContact O-CG 3.38Å; K187-Q191 PolarHBondContact O-N 3.14Å
188	E	91.7	Very high	89.3	Confident	86 Å²	86	58.1 Å²	58.1	40%	0.402	33%	0.334	S	S	.	.	H	α-helix	trans	-51	-51.3	172.3	-70	163.8	-145.2	0	0	110.5	N184 K185 A190 Q191	N184-E188 VanDerWaalsContact O-CG 3.32Å; N184-E188 WeakPolarHBondContact O-CG 3.42Å; N184-E188 PolarHBondContact O-N 2.87Å; K185-E188 IonicContact NZ-OE1 2.67Å; K185-E188 PolarHBondContact NZ-OE1 3.44Å; K185-E188 IonicContact NZ-OE2 3.52Å; K185-E188 PolarHBondContact NZ-OE2 3.14Å; E188-A190 PolarHBondContact O-N 3.29Å; E188-Q191 PolarHBondContact O-N 2.93Å
189	S	87.3	Confident	89.1	Confident	25 Å²	25	56.9 Å²	56.9	18%	0.175	32%	0.319	C	S	.	.	H	α-helix	trans	-68	-14.5	-178.5	-174.1	0	0	0	0	114.8	V169 K185 K187	V169-S189 WeakPolarHBondContact CG1-OG 3.48Å; K185-S189 VanDerWaalsContact O-CB 3.28Å; K185-S189 WeakPolarHBondContact O-CB 3.44Å; K185-S189 PolarHBondContact O-N 2.93Å; K185-S189 VanDerWaalsContact O-N 3.15Å; K187-S189 VanDerWaalsContact C-N 3.3Å; K187-S189 PolarHBondContact O-N 3.39Å
190	A	82.1	Confident	89.1	Confident	0 Å²	0	57.8 Å²	57.8	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-98.3	-42	177.1	0	0	0	0	0	112.1	M119 L186 K187 E188 C192 V193	M119-A190 HydrophobicContact CB-CB 4.13Å; M119-A190 HydrophobicContact CG-CB 4.07Å; M119-A190 HydrophobicContact SD-CB 3.58Å; M119-A190 VanDerWaalsContact SD-CB 3.58Å; L186-A190 WeakPolarHBondContact O-CB 3.44Å; L186-A190 PolarHBondContact O-N 2.96Å; K187-A190 PolarHBondContact O-N 3.41Å; K187-A190 VanDerWaalsContact O-N 3.1Å; E188-A190 PolarHBondContact O-N 3.29Å; A190-C192 VanDerWaalsContact C-N 3.35Å; A190-C192 PolarHBondContact O-N 2.69Å; A190-V193 PolarHBondContact O-N 2.93Å
191	Q	78.5	Confident	89.2	Confident	141 Å²	141	60.3 Å²	60.3	66%	0.659	32%	0.316	S	S	*	.	H	α-helix	trans	-62.7	-36.5	-175.1	-74.8	172.6	1.7	0	0	113.3	K187 E188 V193	K187-Q191 WeakPolarHBondContact O-CB 3.22Å; K187-Q191 VanDerWaalsContact O-CG 3.27Å; K187-Q191 WeakPolarHBondContact O-CG 3.38Å; K187-Q191 PolarHBondContact O-N 3.14Å; E188-Q191 PolarHBondContact O-N 2.93Å; Q191-V193 PolarHBondContact O-N 3.29Å
192	C	68.3	Low	89.1	Confident	119 Å²	119	58.6 Å²	58.6	80%	0.804	31%	0.307	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.4	-7.1	-176.8	-62.6	0	0	0	0	115.3	A190	A190-C192 VanDerWaalsContact C-N 3.35Å; A190-C192 PolarHBondContact O-N 2.69Å
193	V	71.9	Confident	89	Confident	58 Å²	58	58.5 Å²	58.5	35%	0.352	31%	0.306	S	S	.	.	T	Hydrogen-bonded Turn	trans	-117.8	-28.1	-165.5	-177	0	0	0	0	113.2	A190 Q191 N199	A190-V193 PolarHBondContact O-N 2.93Å; Q191-V193 PolarHBondContact O-N 3.29Å; V193-N199 WeakPolarHBondContact CG1-OD1 3.41Å; V193-N199 PolarHBondContact O-ND2 3.13Å
194	G	85.4	Confident	89	Confident	24 Å²	24	60.9 Å²	60.9	25%	0.247	32%	0.323	C	S	.	.			trans	69.8	-170.9	-171.4	0	0	0	0	0	113
195	D	92.8	Very high	88.9	Confident	27 Å²	27	63.7 Å²	63.7	14%	0.144	33%	0.328	C	S	.	.			trans	-83.6	167.4	-174.6	69.7	40.1	0	0	0	114.4	K123 P125 F197 M198 N199 R389	K123-D195 CarbonylContact O-C 3.49Å; K123-D195 WeakPolarHBondContact O-CA 3.45Å; P125-D195 HydrophobicContact CG-CB 4.21Å; D195-F197 PolarHBondContact O-N 2.97Å; D195-F197 VanDerWaalsContact O-N 3.16Å; D195-F197 WeakPolarHBondContact OD1-CA 3.3Å; D195-F197 WeakPolarHBondContact OD1-CB 3.44Å; D195-F197 PolarHBondContact OD1-N 3.19Å; D195-M198 PolarHBondContact O-N 2.85Å; D195-M198 PolarHBondContact OD1-N 3.3Å; D195-N199 PolarHBondContact O-N 3.47Å; D195-N199 PolarHBondContact O-ND2 2.85Å; D195-R389 IonicContact OD1-CZ 3.67Å; D195-R389 IonicContact OD1-NH1 3.23Å; D195-R389 IonicContact OD1-NH2 3.16Å; D195-R389 PolarHBondContact OD1-NH2 2.9Å; D195-R389 VanDerWaalsContact OD1-NH2 3.16Å; D195-R389 IonicContact OD2-CZ 2.71Å; D195-R389 VanDerWaalsContact OD2-CZ 3.23Å; D195-R389 IonicContact OD2-NH1 2.76Å; D195-R389 PolarHBondContact OD2-NH1 3.06Å; D195-R389 IonicContact OD2-NH2 3.72Å; D195-R389 PolarHBondContact OD2-NH2 3.06Å
196	E	93.3	Very high	89	Confident	14 Å²	14	60.1 Å²	60.1	7%	0.065	31%	0.313	C	S	.	.	H	α-helix	trans	-62.6	-18.4	-177.9	73.8	-174.3	128.8	0	0	114.1	K123 F124 Y126 R127 C200 F392	K123-E196 WeakPolarHBondContact O-CB 3.42Å; K123-E196 PolarHBondContact O-N 3.46Å; F124-E196 WeakPolarHBondContact CA-OE1 3.47Å; F124-E196 HydrophobicContact CD1-CB 4Å; F124-E196 HydrophobicContact CE1-CB 4.49Å; Y126-E196 WeakPolarHBondContact CA-OE1 3.46Å; Y126-E196 WeakPolarHBondContact CB-OE1 3.34Å; Y126-E196 HydrophobicContact CD2-CG 3.63Å; Y126-E196 WeakPolarHBondContact CD2-OE1 3.43Å; Y126-E196 HydrophobicContact CE2-CG 4.18Å; Y126-E196 PolarHBondContact N-OE1 2.9Å; R127-E196 WeakPolarHBondContact CG-OE2 3.14Å; R127-E196 IonicContact CZ-OE2 2.71Å; R127-E196 IonicContact NE-OE2 3.67Å; R127-E196 PolarHBondContact NE-OE2 3.28Å; R127-E196 IonicContact NH2-OE2 3.5Å; E196-C200 WeakPolarHBondContact O-CB 3.5Å; E196-C200 PolarHBondContact O-N 2.8Å; E196-F392 HydrophobicContact CG-CE1 3.91Å; E196-F392 HydrophobicContact CG-CZ 4.27Å
197	F	95.3	Very high	89	Confident	20 Å²	20	64.7 Å²	64.7	9%	0.088	33%	0.333	C	S	.	.	H	α-helix	trans	-73.2	-40.1	171.7	172.3	-85.2	0	0	0	111.1	Y126 D195 N199 A203 T204 L388 R389 F392	Y126-F197 HydrophobicContact CE2-CB 3.86Å; D195-F197 PolarHBondContact O-N 2.97Å; D195-F197 VanDerWaalsContact O-N 3.16Å; D195-F197 WeakPolarHBondContact OD1-CA 3.3Å; D195-F197 WeakPolarHBondContact OD1-CB 3.44Å; D195-F197 PolarHBondContact OD1-N 3.19Å; F197-N199 PolarHBondContact O-N 2.95Å; F197-A203 HydrophobicContact CB-CB 4.48Å; F197-A203 HydrophobicContact CD2-CB 3.58Å; F197-A203 HydrophobicContact CE2-CB 3.93Å; F197-A203 HydrophobicContact CG-CB 4.08Å; F197-A203 WeakPolarHBondContact O-CB 3.46Å; F197-T204 HydrophobicContact CZ-CG2 4.33Å; F197-L388 HydrophobicContact CE2-CB 3.92Å; F197-L388 HydrophobicContact CZ-CB 3.86Å; F197-R389 HydrophobicContact CB-CG 4.38Å; F197-R389 HydrophobicContact CD1-CG 3.77Å; F197-R389 HydrophobicContact CD2-CB 4.32Å; F197-R389 HydrophobicContact CD2-CG 3.47Å; F197-R389 VanDerWaalsContact CD2-CG 3.47Å; F197-R389 HydrophobicContact CE1-CG 3.84Å; F197-R389 HydrophobicContact CE2-CB 4.33Å; F197-R389 HydrophobicContact CE2-CG 3.57Å; F197-R389 HydrophobicContact CG-CG 3.6Å; F197-R389 HydrophobicContact CZ-CG 3.75Å; F197-F392 VanDerWaalsContact CA-CE1 3.49Å; F197-F392 HydrophobicContact CB-CD1 3.75Å; F197-F392 HydrophobicContact CB-CE1 3.8Å; F197-F392 HydrophobicContact CD2-CB 3.87Å; F197-F392 AromaticContact CD2-CD1 3.63Å; F197-F392 HydrophobicContact CD2-CD1 3.63Å; F197-F392 HydrophobicContact CD2-CE1 4.41Å; F197-F392 AromaticContact CD2-CG 3.97Å; F197-F392 HydrophobicContact CD2-CG 3.97Å; F197-F392 HydrophobicContact CE2-CB 4.27Å; F197-F392 HydrophobicContact CG-CD1 4.18Å
198	M	92.8	Very high	89	Confident	129 Å²	129	66.3 Å²	66.3	64%	0.635	34%	0.344	S	S	*	.	H	α-helix	trans	-67.3	-27.1	176.7	-56.5	-54.8	-61.4	0	0	112.3	D195 R389	D195-M198 PolarHBondContact O-N 2.85Å; D195-M198 PolarHBondContact OD1-N 3.3Å; M198-R389 PolarHBondContact SD-NH2 2.82Å; M198-R389 VanDerWaalsContact SD-NH2 3.43Å
199	N	90.3	Very high	89.1	Confident	86 Å²	86	64.7 Å²	64.7	46%	0.46	34%	0.336	S	S	.	.	H	α-helix	trans	-99.1	-27.1	-174.2	-71.6	-85.2	0	0	0	114.3	V193 D195 F197 K201	V193-N199 WeakPolarHBondContact CG1-OD1 3.41Å; V193-N199 PolarHBondContact O-ND2 3.13Å; D195-N199 PolarHBondContact O-N 3.47Å; D195-N199 PolarHBondContact O-ND2 2.85Å; F197-N199 PolarHBondContact O-N 2.95Å; N199-K201 PolarHBondContact O-N 3.41Å
200	C	90.8	Very high	89.4	Confident	45 Å²	45	64.7 Å²	64.7	30%	0.304	33%	0.334	S	S	.	.			trans	-80	114	-178.3	-179.2	0	0	0	0	111.4	E196 L202 A203 F392	E196-C200 WeakPolarHBondContact O-CB 3.5Å; E196-C200 PolarHBondContact O-N 2.8Å; C200-L202 PolarHBondContact O-N 2.9Å; C200-A203 HydrophobicContact CB-CB 4.15Å; C200-A203 VanDerWaalsContact O-CB 3.25Å; C200-A203 WeakPolarHBondContact O-CB 3.3Å; C200-A203 PolarHBondContact O-N 3.24Å; C200-F392 HydrophobicContact CB-CE2 4Å; C200-F392 HydrophobicContact CB-CZ 3.69Å
201	K	89.6	Confident	90	Very high	180 Å²	180	66.6 Å²	66.6	78%	0.783	35%	0.346	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.4	-17.5	178.1	-62.6	-178.8	179.5	179.4	0	115.1	N199	N199-K201 PolarHBondContact O-N 3.41Å
202	L	90.8	Very high	90.7	Very high	30 Å²	30	65.3 Å²	65.3	16%	0.157	36%	0.36	C	S	.	.	T	Hydrogen-bonded Turn	trans	-96	-8.6	178.6	-58.2	-179.7	0	0	0	113	M56 P61 C200 T204 R205 A206 F209	M56-L202 HydrophobicContact CE-CD1 4.38Å; P61-L202 HydrophobicContact CB-CD1 3.56Å; P61-L202 HydrophobicContact CG-CD1 4.13Å; C200-L202 PolarHBondContact O-N 2.9Å; L202-T204 PolarHBondContact O-N 3.1Å; L202-R205 CarbonylContact O-C 3.57Å; L202-R205 VanDerWaalsContact O-C 3.27Å; L202-R205 WeakPolarHBondContact O-CA 3.48Å; L202-R205 PolarHBondContact O-N 3.32Å; L202-A206 PolarHBondContact O-N 3.23Å; L202-F209 HydrophobicContact CB-CE2 4.46Å; L202-F209 HydrophobicContact CD2-CE2 4.17Å; L202-F209 HydrophobicContact CD2-CZ 4.17Å
203	A	94.1	Very high	92	Very high	1 Å²	1	63.6 Å²	63.6	1%	0.008	34%	0.343	C	S	.	.	G	3₁₀ helix	trans	-63.9	-42.8	-167.4	0	0	0	0	0	113.8	F197 C200 R205 A206 F392	F197-A203 HydrophobicContact CB-CB 4.48Å; F197-A203 HydrophobicContact CD2-CB 3.58Å; F197-A203 HydrophobicContact CE2-CB 3.93Å; F197-A203 HydrophobicContact CG-CB 4.08Å; F197-A203 WeakPolarHBondContact O-CB 3.46Å; C200-A203 HydrophobicContact CB-CB 4.15Å; C200-A203 VanDerWaalsContact O-CB 3.25Å; C200-A203 WeakPolarHBondContact O-CB 3.3Å; C200-A203 PolarHBondContact O-N 3.24Å; A203-R205 PolarHBondContact O-N 2.92Å; A203-A206 WeakPolarHBondContact O-CB 3.44Å; A203-A206 PolarHBondContact O-N 3.23Å; A203-F392 HydrophobicContact CB-CB 4.34Å; A203-F392 HydrophobicContact CB-CD1 4Å; A203-F392 HydrophobicContact CB-CD2 3.67Å; A203-F392 HydrophobicContact CB-CE1 4.11Å; A203-F392 HydrophobicContact CB-CE2 3.82Å; A203-F392 HydrophobicContact CB-CG 3.73Å; A203-F392 HydrophobicContact CB-CZ 4.03Å
204	T	94.9	Very high	93.1	Very high	83 Å²	83	61.4 Å²	61.4	51%	0.509	33%	0.329	S	S	.	.	G	3₁₀ helix	trans	-69.6	-12.5	174.1	54.3	0	0	0	0	113.6	F197 L202 L388	F197-T204 HydrophobicContact CZ-CG2 4.33Å; L202-T204 PolarHBondContact O-N 3.1Å; T204-L388 HydrophobicContact CG2-CD1 4.33Å; T204-L388 WeakPolarHBondContact O-CD2 3.46Å
205	R	94.5	Very high	93.5	Very high	130 Å²	130	64.2 Å²	64.2	49%	0.491	34%	0.336	S	S	.	.	G	3₁₀ helix	trans	-113.6	10.6	178.6	-67.9	-168.3	61.6	-151.5	-10.7	113.3	L202 A203 K207 D208 F209	L202-R205 CarbonylContact O-C 3.57Å; L202-R205 VanDerWaalsContact O-C 3.27Å; L202-R205 WeakPolarHBondContact O-CA 3.48Å; L202-R205 PolarHBondContact O-N 3.32Å; A203-R205 PolarHBondContact O-N 2.92Å; R205-K207 PolarHBondContact O-N 3.33Å; R205-K207 VanDerWaalsContact O-N 3.12Å; R205-D208 IonicContact CZ-OD2 2.67Å; R205-D208 IonicContact NE-OD2 2.77Å; R205-D208 PolarHBondContact NE-OD2 3.46Å; R205-D208 IonicContact NH2-OD2 2.93Å; R205-D208 PolarHBondContact NH2-OD2 3.43Å; R205-D208 VanDerWaalsContact O-CB 3.28Å; R205-D208 WeakPolarHBondContact O-CB 3.39Å; R205-D208 PolarHBondContact O-N 3.49Å; R205-F209 HydrophobicContact CB-CE2 4.13Å; R205-F209 VanDerWaalsContact O-CD2 3.26Å; R205-F209 WeakPolarHBondContact O-CD2 3.43Å; R205-F209 WeakPolarHBondContact O-CE2 3.27Å
206	A	94.9	Very high	93.7	Very high	1 Å²	1	65.4 Å²	65.4	1%	0.008	35%	0.349	C	S	.	.	G	3₁₀ helix	trans	-56.5	-34.4	-175.6	0	0	0	0	0	112.8	L202 A203 D208 F209 L210 F392 Y395	L202-A206 PolarHBondContact O-N 3.23Å; A203-A206 WeakPolarHBondContact O-CB 3.44Å; A203-A206 PolarHBondContact O-N 3.23Å; A206-D208 VanDerWaalsContact C-N 3.26Å; A206-D208 PolarHBondContact O-N 3.48Å; A206-F209 PolarHBondContact O-N 2.91Å; A206-L210 WeakPolarHBondContact O-CG 3.48Å; A206-F392 VanDerWaalsContact CB-CA 3.5Å; A206-F392 HydrophobicContact CB-CB 3.92Å; A206-F392 HydrophobicContact CB-CD2 4.18Å; A206-Y395 HydrophobicContact CB-CG 4.34Å
207	K	95.3	Very high	93.8	Very high	97 Å²	97	67.2 Å²	67.2	42%	0.422	36%	0.358	S	S	.	.	G	3₁₀ helix	trans	-55.7	-36.7	176	-165.9	174.1	-172	166.8	0	112.7	R205 F209 L210 E387 Y391	R205-K207 PolarHBondContact O-N 3.33Å; R205-K207 VanDerWaalsContact O-N 3.12Å; K207-F209 PolarHBondContact O-N 3.28Å; K207-L210 PolarHBondContact O-N 3.18Å; K207-E387 IonicContact NZ-OE1 2.79Å; K207-E387 PolarHBondContact NZ-OE1 2.96Å; K207-Y391 HydrophobicContact CB-CD1 4.29Å; K207-Y391 HydrophobicContact CB-CD2 4.07Å; K207-Y391 HydrophobicContact CB-CE2 4.48Å; K207-Y391 HydrophobicContact CB-CG 3.96Å; K207-Y391 HydrophobicContact CD-CD2 3.82Å; K207-Y391 HydrophobicContact CD-CE1 4.43Å; K207-Y391 HydrophobicContact CD-CE2 3.48Å; K207-Y391 VanDerWaalsContact CD-CE2 3.48Å; K207-Y391 HydrophobicContact CD-CG 4.43Å; K207-Y391 VanDerWaalsContact CE-CE2 3.49Å; K207-Y391 VanDerWaalsContact CE-CZ 3.48Å; K207-Y391 WeakPolarHBondContact CE-OH 3.24Å; K207-Y391 HydrophobicContact CG-CD1 4.1Å; K207-Y391 HydrophobicContact CG-CD2 3.99Å; K207-Y391 HydrophobicContact CG-CE1 4Å; K207-Y391 HydrophobicContact CG-CE2 3.9Å; K207-Y391 HydrophobicContact CG-CG 4.08Å
208	D	94.8	Very high	93.9	Very high	97 Å²	97	66.9 Å²	66.9	52%	0.519	36%	0.356	S	S	.	.	G	3₁₀ helix	trans	-65	-24.7	-177.5	-53.8	9.4	0	0	0	113.2	R205 A206	R205-D208 IonicContact CZ-OD2 2.67Å; R205-D208 IonicContact NE-OD2 2.77Å; R205-D208 PolarHBondContact NE-OD2 3.46Å; R205-D208 IonicContact NH2-OD2 2.93Å; R205-D208 PolarHBondContact NH2-OD2 3.43Å; R205-D208 VanDerWaalsContact O-CB 3.28Å; R205-D208 WeakPolarHBondContact O-CB 3.39Å; R205-D208 PolarHBondContact O-N 3.49Å; A206-D208 VanDerWaalsContact C-N 3.26Å; A206-D208 PolarHBondContact O-N 3.48Å
209	F	93.6	Very high	94.2	Very high	51 Å²	51	62.6 Å²	62.6	22%	0.224	34%	0.341	C	S	.	.	G	3₁₀ helix	trans	-103.7	-6.9	-174	-53.3	-73.3	0	0	0	113.5	P61 L202 R205 A206 K207 Y395	P61-F209 HydrophobicContact CG-CD1 3.62Å; P61-F209 HydrophobicContact CG-CD2 4.49Å; P61-F209 HydrophobicContact CG-CE1 3.63Å; P61-F209 HydrophobicContact CG-CG 4.08Å; P61-F209 HydrophobicContact CG-CZ 4.1Å; L202-F209 HydrophobicContact CB-CE2 4.46Å; L202-F209 HydrophobicContact CD2-CE2 4.17Å; L202-F209 HydrophobicContact CD2-CZ 4.17Å; R205-F209 HydrophobicContact CB-CE2 4.13Å; R205-F209 VanDerWaalsContact O-CD2 3.26Å; R205-F209 WeakPolarHBondContact O-CD2 3.43Å; R205-F209 WeakPolarHBondContact O-CE2 3.27Å; A206-F209 PolarHBondContact O-N 2.91Å; K207-F209 PolarHBondContact O-N 3.28Å; F209-Y395 HydrophobicContact CB-CD2 4.39Å; F209-Y395 HydrophobicContact CB-CE2 4.33Å; F209-Y395 HydrophobicContact CD2-CE2 4.44Å
210	L	94.2	Very high	94.5	Very high	25 Å²	25	64.1 Å²	64.1	13%	0.131	35%	0.348	C	S	.	.	S	Bend	trans	-89.9	138.1	-173.4	-75.6	175.6	0	0	0	112.2	L62 A206 K207 I214 Y391 L394	L62-L210 HydrophobicContact CD1-CD2 3.83Å; A206-L210 WeakPolarHBondContact O-CG 3.48Å; K207-L210 PolarHBondContact O-N 3.18Å; L210-I214 HydrophobicContact CB-CB 4.5Å; L210-I214 HydrophobicContact CB-CG2 4.36Å; L210-I214 HydrophobicContact CD1-CG2 4.45Å; L210-I214 HydrophobicContact CD2-CB 4.47Å; L210-I214 HydrophobicContact CD2-CD1 3.91Å; L210-I214 HydrophobicContact CD2-CG1 3.79Å; L210-Y391 HydrophobicContact CD1-CD1 3.8Å; L210-Y391 WeakPolarHBondContact CD1-O 3.46Å; L210-L394 HydrophobicContact CD1-CB 4.07Å
211	P	93.4	Very high	94.9	Very high	40 Å²	40	63 Å²	63	26%	0.26	34%	0.341	S	S	.	.			trans	-56.9	145.6	166.2	-23.9	34.3	0	0	0	112.1	D213 I214	P211-D213 WeakPolarHBondContact CB-OD1 3.15Å; P211-D213 PolarHBondContact O-N 3.01Å; P211-I214 VanDerWaalsContact O-CB 3.26Å; P211-I214 WeakPolarHBondContact O-CB 3.44Å; P211-I214 VanDerWaalsContact O-CG2 3.3Å; P211-I214 WeakPolarHBondContact O-CG2 3.13Å; P211-I214 PolarHBondContact O-N 3.22Å
212	A	94.1	Very high	95.3	Very high	115 Å²	115	59 Å²	59	95%	0.95	32%	0.321	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.2	-27.6	179.7	0	0	0	0	0	112.9
213	D	95.4	Very high	95.6	Very high	83 Å²	83	61.4 Å²	61.4	44%	0.444	33%	0.332	S	S	.	.	T	Hydrogen-bonded Turn	trans	-93.1	10	178.7	66.4	-48.1	0	0	0	113.9	P211 Q215 A216 Q217	P211-D213 WeakPolarHBondContact CB-OD1 3.15Å; P211-D213 PolarHBondContact O-N 3.01Å; D213-Q215 PolarHBondContact O-N 3.19Å; D213-A216 WeakPolarHBondContact O-CA 3.47Å; D213-A216 WeakPolarHBondContact O-CB 3.21Å; D213-A216 PolarHBondContact O-N 3.41Å; D213-Q217 PolarHBondContact O-N 2.89Å; D213-Q217 PolarHBondContact OD1-NE2 3.05Å; D213-Q217 VanDerWaalsContact OD1-NE2 3.09Å; D213-Q217 VanDerWaalsContact OD2-CG 3.25Å; D213-Q217 WeakPolarHBondContact OD2-CG 3.29Å; D213-Q217 PolarHBondContact OD2-NE2 3.46Å
214	I	94.8	Very high	95.8	Very high	11 Å²	11	65.2 Å²	65.2	6%	0.056	35%	0.351	C	S	.	.	H	α-helix	trans	-48.6	-33.6	-175.3	-176.3	62.8	0	0	0	114.5	L210 P211 Q217 F218 L394 H398	L210-I214 HydrophobicContact CB-CB 4.5Å; L210-I214 HydrophobicContact CB-CG2 4.36Å; L210-I214 HydrophobicContact CD1-CG2 4.45Å; L210-I214 HydrophobicContact CD2-CB 4.47Å; L210-I214 HydrophobicContact CD2-CD1 3.91Å; L210-I214 HydrophobicContact CD2-CG1 3.79Å; P211-I214 VanDerWaalsContact O-CB 3.26Å; P211-I214 WeakPolarHBondContact O-CB 3.44Å; P211-I214 VanDerWaalsContact O-CG2 3.3Å; P211-I214 WeakPolarHBondContact O-CG2 3.13Å; P211-I214 PolarHBondContact O-N 3.22Å; I214-Q217 PolarHBondContact O-N 3Å; I214-F218 WeakPolarHBondContact O-CB 3.33Å; I214-F218 PolarHBondContact O-N 3.39Å; I214-L394 HydrophobicContact CG1-CB 4.18Å; I214-L394 HydrophobicContact CG2-CD1 4.46Å; I214-H398 HydrophobicContact CD1-CB 4.18Å
215	Q	94.8	Very high	96	Very high	83 Å²	83	61.3 Å²	61.3	39%	0.388	33%	0.327	S	S	.	.	H	α-helix	trans	-67.3	-38.6	176.8	-69.6	-72.3	11.3	0	0	112.6	D213 A219	D213-Q215 PolarHBondContact O-N 3.19Å; Q215-A219 PolarHBondContact O-N 2.97Å; Q215-A219 VanDerWaalsContact O-N 3.13Å
216	A	96.7	Very high	96.2	Very high	52 Å²	52	60 Å²	60	43%	0.43	32%	0.323	S	S	.	.	H	α-helix	trans	-70.4	-42.5	173.7	0	0	0	0	0	110.6	D213 F218 A219 I220	D213-A216 WeakPolarHBondContact O-CA 3.47Å; D213-A216 WeakPolarHBondContact O-CB 3.21Å; D213-A216 PolarHBondContact O-N 3.41Å; A216-F218 PolarHBondContact O-N 2.92Å; A216-A219 PolarHBondContact O-N 3.4Å; A216-I220 VanDerWaalsContact O-CG1 3.26Å; A216-I220 WeakPolarHBondContact O-CG1 3.37Å; A216-I220 PolarHBondContact O-N 3.4Å
217	Q	96.1	Very high	96.4	Very high	52 Å²	52	63 Å²	63	24%	0.243	34%	0.338	C	S	.	.	H	α-helix	trans	-57.3	-48.1	173.9	-60.9	-173.7	7.5	0	0	111.5	D213 I214 A219 I220 S221	D213-Q217 PolarHBondContact O-N 2.89Å; D213-Q217 PolarHBondContact OD1-NE2 3.05Å; D213-Q217 VanDerWaalsContact OD1-NE2 3.09Å; D213-Q217 VanDerWaalsContact OD2-CG 3.25Å; D213-Q217 WeakPolarHBondContact OD2-CG 3.29Å; D213-Q217 PolarHBondContact OD2-NE2 3.46Å; I214-Q217 PolarHBondContact O-N 3Å; Q217-A219 VanDerWaalsContact C-N 3.35Å; Q217-A219 PolarHBondContact O-N 3.08Å; Q217-I220 PolarHBondContact O-N 3.06Å; Q217-S221 WeakPolarHBondContact O-CB 3.25Å; Q217-S221 PolarHBondContact O-N 3.16Å; Q217-S221 PolarHBondContact O-OG 3.17Å; Q217-S221 VanDerWaalsContact O-OG 3.1Å
218	F	96.9	Very high	96.5	Very high	13 Å²	13	59.8 Å²	59.8	6%	0.057	33%	0.325	C	S	.	.	H	α-helix	trans	-56.1	-46.1	175.2	167.2	-112.5	0	0	0	112.4	I214 A216 I220 S221 R222 C331 H334 E335 L394 L397	I214-F218 WeakPolarHBondContact O-CB 3.33Å; I214-F218 PolarHBondContact O-N 3.39Å; A216-F218 PolarHBondContact O-N 2.92Å; F218-I220 PolarHBondContact O-N 3.24Å; F218-S221 PolarHBondContact O-N 2.98Å; F218-R222 VanDerWaalsContact O-CB 3.24Å; F218-R222 WeakPolarHBondContact O-CB 3.41Å; F218-R222 PolarHBondContact O-N 3.01Å; F218-C331 HydrophobicContact CE2-CB 4.35Å; F218-C331 HydrophobicContact CZ-CB 4.24Å; F218-H334 AromaticContact CE1-CD2 3.99Å; F218-H334 AromaticContact CZ-CD2 3.98Å; F218-E335 HydrophobicContact CE1-CG 4.06Å; F218-E335 HydrophobicContact CZ-CG 4.08Å; F218-L394 HydrophobicContact CB-CD2 4.46Å; F218-L394 HydrophobicContact CG-CD2 4.47Å; F218-L397 HydrophobicContact CD2-CD1 3.79Å; F218-L397 HydrophobicContact CD2-CD2 4.23Å; F218-L397 HydrophobicContact CD2-CG 4.45Å; F218-L397 HydrophobicContact CE2-CD1 3.5Å; F218-L397 HydrophobicContact CE2-CD2 3.82Å; F218-L397 HydrophobicContact CE2-CG 4.26Å; F218-L397 HydrophobicContact CZ-CD1 4.18Å
219	A	97.7	Very high	96.7	Very high	39 Å²	39	57 Å²	57	32%	0.322	31%	0.308	S	S	.	.	H	α-helix	trans	-61.4	-43.3	178.5	0	0	0	0	0	112.2	Q215 A216 Q217 E223	Q215-A219 PolarHBondContact O-N 2.97Å; Q215-A219 VanDerWaalsContact O-N 3.13Å; A216-A219 PolarHBondContact O-N 3.4Å; Q217-A219 VanDerWaalsContact C-N 3.35Å; Q217-A219 PolarHBondContact O-N 3.08Å; A219-E223 PolarHBondContact O-N 3.41Å; A219-E223 VanDerWaalsContact O-N 3.14Å
220	I	97.9	Very high	96.9	Very high	118 Å²	118	57.1 Å²	57.1	61%	0.605	31%	0.311	S	S	*	.	H	α-helix	trans	-65.3	-50.5	176.7	-65	166.6	0	0	0	110.5	A216 Q217 F218 R222 E223 L224	A216-I220 VanDerWaalsContact O-CG1 3.26Å; A216-I220 WeakPolarHBondContact O-CG1 3.37Å; A216-I220 PolarHBondContact O-N 3.4Å; Q217-I220 PolarHBondContact O-N 3.06Å; F218-I220 PolarHBondContact O-N 3.24Å; I220-R222 VanDerWaalsContact C-N 3.33Å; I220-R222 PolarHBondContact O-N 3.3Å; I220-E223 PolarHBondContact O-N 3.15Å; I220-L224 WeakPolarHBondContact O-CB 3.49Å; I220-L224 PolarHBondContact O-N 2.9Å
221	S	97.8	Very high	97.1	Very high	23 Å²	23	59.3 Å²	59.3	16%	0.161	33%	0.328	C	S	.	.	H	α-helix	trans	-59.9	-41.8	179.6	-64.5	0	0	0	0	112	Q217 F218 L224 I225	Q217-S221 WeakPolarHBondContact O-CB 3.25Å; Q217-S221 PolarHBondContact O-N 3.16Å; Q217-S221 PolarHBondContact O-OG 3.17Å; Q217-S221 VanDerWaalsContact O-OG 3.1Å; F218-S221 PolarHBondContact O-N 2.98Å; S221-L224 PolarHBondContact O-N 3.06Å; S221-I225 WeakPolarHBondContact O-CB 3.47Å; S221-I225 VanDerWaalsContact O-CG1 3.27Å; S221-I225 WeakPolarHBondContact O-CG1 3.09Å; S221-I225 PolarHBondContact O-N 2.73Å
222	R	98.3	Very high	97.4	Very high	94 Å²	94	58.6 Å²	58.6	36%	0.355	32%	0.321	S	S	.	.	H	α-helix	trans	-60.9	-45.1	174.8	179.7	-175.9	61.8	160.8	-7.1	112.2	F218 I220 R226 C331 E335	F218-R222 VanDerWaalsContact O-CB 3.24Å; F218-R222 WeakPolarHBondContact O-CB 3.41Å; F218-R222 PolarHBondContact O-N 3.01Å; I220-R222 VanDerWaalsContact C-N 3.33Å; I220-R222 PolarHBondContact O-N 3.3Å; R222-R226 VanDerWaalsContact O-CB 3.28Å; R222-R226 WeakPolarHBondContact O-CB 3.5Å; R222-R226 PolarHBondContact O-N 3.14Å; R222-C331 HydrophobicContact CG-CB 4.34Å; R222-E335 IonicContact CZ-OE1 3.28Å; R222-E335 IonicContact CZ-OE2 2.75Å; R222-E335 IonicContact NE-OE2 3.42Å; R222-E335 IonicContact NH1-OE1 2.73Å; R222-E335 PolarHBondContact NH1-OE1 2.68Å; R222-E335 IonicContact NH1-OE2 3.51Å; R222-E335 PolarHBondContact NH1-OE2 2.84Å; R222-E335 IonicContact NH2-OE1 2.68Å
223	E	98.4	Very high	97.6	Very high	82 Å²	82	55.9 Å²	55.9	38%	0.383	29%	0.289	S	S	.	.	H	α-helix	trans	-68.6	-41.4	179.1	176.4	54.4	-160.5	0	0	112.2	A219 I220 R226 N227	A219-E223 PolarHBondContact O-N 3.41Å; A219-E223 VanDerWaalsContact O-N 3.14Å; I220-E223 PolarHBondContact O-N 3.15Å; E223-R226 VanDerWaalsContact CD-NH2 3.31Å; E223-R226 PolarHBondContact O-N 3.08Å; E223-R226 IonicContact OE1-CZ 3.92Å; E223-R226 IonicContact OE1-NE 3.9Å; E223-R226 IonicContact OE1-NH2 2.73Å; E223-R226 PolarHBondContact OE1-NH2 3.32Å; E223-R226 IonicContact OE2-CZ 3.36Å; E223-R226 IonicContact OE2-NE 3.92Å; E223-R226 PolarHBondContact OE2-NE 2.81Å; E223-R226 IonicContact OE2-NH2 2.76Å; E223-R226 PolarHBondContact OE2-NH2 3.48Å; E223-R226 VanDerWaalsContact OE2-NH2 3.14Å; E223-N227 PolarHBondContact O-N 3.49Å; E223-N227 PolarHBondContact O-ND2 3.12Å; E223-N227 VanDerWaalsContact O-ND2 3.13Å; E223-N227 PolarHBondContact OE1-ND2 3.37Å
224	L	98.2	Very high	97.7	Very high	80 Å²	80	58.4 Å²	58.4	42%	0.419	30%	0.296	S	S	.	.	H	α-helix	trans	-57.5	-51.9	172.8	175.7	60.5	0	0	0	111.3	I220 S221 R226 N227 I228	I220-L224 WeakPolarHBondContact O-CB 3.49Å; I220-L224 PolarHBondContact O-N 2.9Å; S221-L224 PolarHBondContact O-N 3.06Å; L224-R226 VanDerWaalsContact C-N 3.34Å; L224-R226 PolarHBondContact O-N 3.28Å; L224-N227 PolarHBondContact O-N 2.93Å; L224-N227 VanDerWaalsContact O-N 3.14Å; L224-I228 HydrophobicContact CD1-CD1 4.04Å; L224-I228 HydrophobicContact CD1-CG1 4.41Å; L224-I228 HydrophobicContact CG-CD1 3.95Å; L224-I228 WeakPolarHBondContact O-CG1 3.34Å; L224-I228 PolarHBondContact O-N 3.18Å
225	I	98.5	Very high	97.9	Very high	1 Å²	1	61.3 Å²	61.3	1%	0.005	31%	0.311	C	S	.	.	H	α-helix	trans	-67.3	-34.3	-178.4	-68.6	167.1	0	0	0	111.4	S221 N227 I228 Y229 L324 Y327 T401 I404	S221-I225 WeakPolarHBondContact O-CB 3.47Å; S221-I225 VanDerWaalsContact O-CG1 3.27Å; S221-I225 WeakPolarHBondContact O-CG1 3.09Å; S221-I225 PolarHBondContact O-N 2.73Å; I225-N227 PolarHBondContact O-N 3.03Å; I225-I228 PolarHBondContact O-N 3.37Å; I225-Y229 WeakPolarHBondContact O-CB 3.35Å; I225-Y229 PolarHBondContact O-N 2.85Å; I225-L324 HydrophobicContact CG2-CD2 3.82Å; I225-Y327 HydrophobicContact CB-CD1 3.99Å; I225-Y327 HydrophobicContact CB-CE1 4.04Å; I225-Y327 HydrophobicContact CD1-CD1 3.84Å; I225-Y327 HydrophobicContact CD1-CD2 4.06Å; I225-Y327 HydrophobicContact CD1-CE1 3.57Å; I225-Y327 HydrophobicContact CD1-CE2 3.82Å; I225-Y327 HydrophobicContact CD1-CG 4.09Å; I225-Y327 HydrophobicContact CG1-CE1 4.39Å; I225-Y327 HydrophobicContact CG2-CD1 3.46Å; I225-Y327 VanDerWaalsContact CG2-CD1 3.46Å; I225-Y327 HydrophobicContact CG2-CE1 4.05Å; I225-Y327 HydrophobicContact CG2-CG 4Å; I225-T401 HydrophobicContact CD1-CG2 4.36Å; I225-I404 HydrophobicContact CD1-CB 4.19Å; I225-I404 HydrophobicContact CD1-CG1 4.19Å; I225-I404 HydrophobicContact CD1-CG2 4.03Å; I225-I404 HydrophobicContact CG1-CG2 4.1Å
226	R	98.4	Very high	98	Very high	104 Å²	104	59.4 Å²	59.4	39%	0.392	30%	0.3	S	S	.	.	H	α-helix	trans	-59.5	-44.5	170.4	-170.3	-171.7	71.2	75.4	10.9	111.5	R222 E223 L224 Y229 N230	R222-R226 VanDerWaalsContact O-CB 3.28Å; R222-R226 WeakPolarHBondContact O-CB 3.5Å; R222-R226 PolarHBondContact O-N 3.14Å; E223-R226 VanDerWaalsContact CD-NH2 3.31Å; E223-R226 PolarHBondContact O-N 3.08Å; E223-R226 IonicContact OE1-CZ 3.92Å; E223-R226 IonicContact OE1-NE 3.9Å; E223-R226 IonicContact OE1-NH2 2.73Å; E223-R226 PolarHBondContact OE1-NH2 3.32Å; E223-R226 IonicContact OE2-CZ 3.36Å; E223-R226 IonicContact OE2-NE 3.92Å; E223-R226 PolarHBondContact OE2-NE 2.81Å; E223-R226 IonicContact OE2-NH2 2.76Å; E223-R226 PolarHBondContact OE2-NH2 3.48Å; E223-R226 VanDerWaalsContact OE2-NH2 3.14Å; L224-R226 VanDerWaalsContact C-N 3.34Å; L224-R226 PolarHBondContact O-N 3.28Å; R226-Y229 PolarHBondContact O-N 2.78Å; R226-N230 PolarHBondContact NH1-ND2 3.07Å; R226-N230 VanDerWaalsContact NH1-ND2 3.16Å; R226-N230 PolarHBondContact O-N 3.07Å; R226-N230 PolarHBondContact O-ND2 3Å; R226-N230 VanDerWaalsContact O-ND2 3.13Å
227	N	98.4	Very high	98.1	Very high	63 Å²	63	59 Å²	59	34%	0.337	29%	0.29	S	S	.	.	H	α-helix	trans	-72.1	-34	179.3	-71.2	-37.7	0	0	0	113.2	E223 L224 I225 S231	E223-N227 PolarHBondContact O-N 3.49Å; E223-N227 PolarHBondContact O-ND2 3.12Å; E223-N227 VanDerWaalsContact O-ND2 3.13Å; E223-N227 PolarHBondContact OE1-ND2 3.37Å; L224-N227 PolarHBondContact O-N 2.93Å; L224-N227 VanDerWaalsContact O-N 3.14Å; I225-N227 PolarHBondContact O-N 3.03Å; N227-S231 WeakPolarHBondContact O-CB 3.48Å; N227-S231 PolarHBondContact O-N 3.19Å; N227-S231 VanDerWaalsContact O-N 3.12Å; N227-S231 PolarHBondContact O-OG 3.08Å
228	I	98.4	Very high	98.2	Very high	29 Å²	29	63.1 Å²	63.1	15%	0.149	30%	0.304	C	S	.	.	H	α-helix	trans	-60.9	-52.3	168.9	-66.4	165.1	0	0	0	109.7	L224 I225 N230 S231 F232 F320 L324 L408	L224-I228 HydrophobicContact CD1-CD1 4.04Å; L224-I228 HydrophobicContact CD1-CG1 4.41Å; L224-I228 HydrophobicContact CG-CD1 3.95Å; L224-I228 WeakPolarHBondContact O-CG1 3.34Å; L224-I228 PolarHBondContact O-N 3.18Å; I225-I228 PolarHBondContact O-N 3.37Å; I228-N230 VanDerWaalsContact C-N 3.35Å; I228-N230 PolarHBondContact O-N 2.86Å; I228-S231 PolarHBondContact O-N 3.09Å; I228-F232 HydrophobicContact CG2-CD2 3.75Å; I228-F232 HydrophobicContact CG2-CE2 3.99Å; I228-F232 WeakPolarHBondContact O-CD2 3.49Å; I228-F232 PolarHBondContact O-N 3.49Å; I228-F320 HydrophobicContact CG2-CE1 4.16Å; I228-F320 HydrophobicContact CG2-CZ 4.36Å; I228-L324 HydrophobicContact CG2-CD1 3.93Å; I228-L324 HydrophobicContact CG2-CD2 4.07Å; I228-L408 HydrophobicContact CD1-CD2 4.32Å
229	Y	98.7	Very high	98.3	Very high	40 Å²	40	62.9 Å²	62.9	16%	0.157	30%	0.304	C	S	.	.	H	α-helix	trans	-52.1	-50.6	176.2	177.2	-84.4	0	0	0	112	I225 R226 S231 F232 H233 L321 L324 Q325 K328	I225-Y229 WeakPolarHBondContact O-CB 3.35Å; I225-Y229 PolarHBondContact O-N 2.85Å; R226-Y229 PolarHBondContact O-N 2.78Å; Y229-S231 PolarHBondContact O-N 2.85Å; Y229-F232 PolarHBondContact O-N 2.79Å; Y229-H233 HydrophobicContact CE1-CB 4.46Å; Y229-H233 WeakPolarHBondContact O-CB 3.5Å; Y229-H233 PolarHBondContact O-N 3.17Å; Y229-L321 HydrophobicContact CD2-CD2 3.84Å; Y229-L321 HydrophobicContact CE2-CD2 3.89Å; Y229-L321 HydrophobicContact CG-CD2 4.39Å; Y229-L324 HydrophobicContact CD2-CB 3.84Å; Y229-Q325 HydrophobicContact CE2-CB 4.13Å; Y229-K328 HydrophobicContact CD1-CD 4.27Å; Y229-K328 VanDerWaalsContact CD1-NZ 3.29Å; Y229-K328 HydrophobicContact CD2-CD 3.92Å; Y229-K328 HydrophobicContact CE2-CD 4.45Å; Y229-K328 HydrophobicContact CG-CD 3.84Å; Y229-K328 VanDerWaalsContact CZ-NZ 3.31Å
230	N	98.6	Very high	98.3	Very high	52 Å²	52	65.6 Å²	65.6	28%	0.278	31%	0.31	S	S	.	.	H	α-helix	trans	-61.4	-29.2	-179.8	-66.8	-25.5	0	0	0	113.2	R226 I228 K234	R226-N230 PolarHBondContact NH1-ND2 3.07Å; R226-N230 VanDerWaalsContact NH1-ND2 3.16Å; R226-N230 PolarHBondContact O-N 3.07Å; R226-N230 PolarHBondContact O-ND2 3Å; R226-N230 VanDerWaalsContact O-ND2 3.13Å; I228-N230 VanDerWaalsContact C-N 3.35Å; I228-N230 PolarHBondContact O-N 2.86Å; N230-K234 WeakPolarHBondContact O-CD 3.43Å; N230-K234 VanDerWaalsContact O-CG 3.3Å; N230-K234 WeakPolarHBondContact O-CG 3.37Å
231	S	98.2	Very high	98.3	Very high	71 Å²	71	66.1 Å²	66.1	50%	0.497	30%	0.304	S	S	.	.	H	α-helix	trans	-82.2	-43.7	-179.8	-56.6	0	0	0	0	111.4	N227 I228 Y229 H233 K234 L235	N227-S231 WeakPolarHBondContact O-CB 3.48Å; N227-S231 PolarHBondContact O-N 3.19Å; N227-S231 VanDerWaalsContact O-N 3.12Å; N227-S231 PolarHBondContact O-OG 3.08Å; I228-S231 PolarHBondContact O-N 3.09Å; Y229-S231 PolarHBondContact O-N 2.85Å; S231-H233 VanDerWaalsContact C-N 3.35Å; S231-K234 PolarHBondContact O-N 3.07Å; S231-L235 PolarHBondContact O-N 3.15Å
232	F	98.4	Very high	98.2	Very high	25 Å²	25	67 Å²	67	11%	0.11	31%	0.307	C	S	.	.	H	α-helix	trans	-69	-31	175.9	-84.9	-94	0	0	0	112.9	I228 Y229 L235 R236 L317 F320 L321 T411 I414	I228-F232 HydrophobicContact CG2-CD2 3.75Å; I228-F232 HydrophobicContact CG2-CE2 3.99Å; I228-F232 WeakPolarHBondContact O-CD2 3.49Å; I228-F232 PolarHBondContact O-N 3.49Å; Y229-F232 PolarHBondContact O-N 2.79Å; F232-L235 HydrophobicContact CD1-CD2 4.39Å; F232-L235 HydrophobicContact CE1-CD2 4.4Å; F232-L235 PolarHBondContact O-N 2.96Å; F232-R236 PolarHBondContact O-N 3.18Å; F232-L317 HydrophobicContact CD1-CD2 3.78Å; F232-L317 HydrophobicContact CE1-CD2 4.33Å; F232-F320 AromaticContact CD1-CD1 3.6Å; F232-F320 HydrophobicContact CD1-CD1 3.6Å; F232-F320 AromaticContact CD1-CE1 3.98Å; F232-F320 HydrophobicContact CD1-CE1 3.98Å; F232-F320 HydrophobicContact CD2-CD1 4.32Å; F232-F320 AromaticContact CD2-CE1 3.95Å; F232-F320 HydrophobicContact CD2-CE1 3.95Å; F232-F320 AromaticContact CE1-CD1 3.75Å; F232-F320 HydrophobicContact CE1-CD1 3.75Å; F232-F320 AromaticContact CE1-CE1 3.88Å; F232-F320 HydrophobicContact CE1-CE1 3.88Å; F232-F320 HydrophobicContact CE2-CD1 4.46Å; F232-F320 AromaticContact CE2-CE1 3.86Å; F232-F320 HydrophobicContact CE2-CE1 3.86Å; F232-F320 AromaticContact CG-CD1 3.9Å; F232-F320 HydrophobicContact CG-CD1 3.9Å; F232-F320 HydrophobicContact CG-CE1 4.01Å; F232-F320 HydrophobicContact CZ-CD1 4.19Å; F232-F320 AromaticContact CZ-CE1 3.82Å; F232-F320 HydrophobicContact CZ-CE1 3.82Å; F232-L321 HydrophobicContact CB-CD2 3.87Å; F232-L321 HydrophobicContact CB-CG 4.39Å; F232-T411 HydrophobicContact CE1-CG2 4.35Å; F232-T411 HydrophobicContact CZ-CG2 3.82Å; F232-T411 WeakPolarHBondContact CZ-OG1 3.41Å; F232-I414 HydrophobicContact CE1-CD1 4.4Å
233	H	98.5	Very high	98.2	Very high	59 Å²	59	62.8 Å²	62.8	27%	0.273	29%	0.292	S	S	.	.	H	α-helix	trans	-63.2	-51.1	173.7	-169.8	-66.2	0	0	0	110	Y229 S231 L235 R236 D237 L321	Y229-H233 HydrophobicContact CE1-CB 4.46Å; Y229-H233 WeakPolarHBondContact O-CB 3.5Å; Y229-H233 PolarHBondContact O-N 3.17Å; S231-H233 VanDerWaalsContact C-N 3.35Å; H233-L235 PolarHBondContact O-N 2.86Å; H233-R236 PolarHBondContact CE1-NH2 2.93Å; H233-R236 PolarHBondContact NE2-NH2 3.41Å; H233-R236 WeakPolarHBondContact O-CB 3.4Å; H233-R236 PolarHBondContact O-N 2.92Å; H233-R236 VanDerWaalsContact O-N 3.08Å; H233-D237 IonicContact CE1-OD1 2.67Å; H233-D237 PolarHBondContact CE1-OD1 3.25Å; H233-D237 IonicContact CE1-OD2 3.33Å; H233-D237 PolarHBondContact CE1-OD2 2.94Å; H233-D237 IonicContact CG-OD2 2.73Å; H233-D237 IonicContact ND1-OD1 3.76Å; H233-D237 PolarHBondContact ND1-OD1 2.98Å; H233-D237 IonicContact ND1-OD2 3.26Å; H233-D237 PolarHBondContact ND1-OD2 2.99Å; H233-D237 PolarHBondContact O-N 3.32Å; H233-D237 VanDerWaalsContact O-OD2 3.07Å; H233-L321 HydrophobicContact CB-CD2 4.2Å
234	K	98.5	Very high	98.1	Very high	136 Å²	136	61.4 Å²	61.4	59%	0.591	29%	0.292	S	S	*	.	H	α-helix	trans	-56.2	-39.6	174.4	-69.5	169.1	-175	177.3	0	111.9	N230 S231 D237 R238	N230-K234 WeakPolarHBondContact O-CD 3.43Å; N230-K234 VanDerWaalsContact O-CG 3.3Å; N230-K234 WeakPolarHBondContact O-CG 3.37Å; S231-K234 PolarHBondContact O-N 3.07Å; K234-D237 CarbonylContact O-C 3.55Å; K234-D237 PolarHBondContact O-N 3.1Å; K234-R238 WeakPolarHBondContact O-CG 3.38Å; K234-R238 PolarHBondContact O-N 2.82Å
235	L	97.9	Very high	98	Very high	71 Å²	71	63.9 Å²	63.9	37%	0.372	30%	0.296	S	S	.	.	H	α-helix	trans	-65.3	-41.5	176.7	-177.5	58.1	0	0	0	112.2	S231 F232 H233 R238 A239 L317	S231-L235 PolarHBondContact O-N 3.15Å; F232-L235 HydrophobicContact CD1-CD2 4.39Å; F232-L235 HydrophobicContact CE1-CD2 4.4Å; F232-L235 PolarHBondContact O-N 2.96Å; H233-L235 PolarHBondContact O-N 2.86Å; L235-R238 WeakPolarHBondContact O-CA 3.29Å; L235-R238 WeakPolarHBondContact O-CB 3.37Å; L235-R238 PolarHBondContact O-N 2.9Å; L235-R238 VanDerWaalsContact O-N 3.08Å; L235-A239 PolarHBondContact O-N 3.39Å; L235-L317 HydrophobicContact CB-CD2 4.45Å; L235-L317 HydrophobicContact CD2-CD2 3.88Å; L235-L317 HydrophobicContact CG-CD1 4.34Å; L235-L317 HydrophobicContact CG-CD2 4Å
236	R	98.3	Very high	97.9	Very high	44 Å²	44	64.4 Å²	64.4	17%	0.166	30%	0.3	C	S	.	.	H	α-helix	trans	-58.9	-48.7	170.6	-169	-71.7	-51.5	-85.9	2.2	110.9	F232 H233 R238 A239 E240 V314 L317 N318 L321	F232-R236 PolarHBondContact O-N 3.18Å; H233-R236 PolarHBondContact CE1-NH2 2.93Å; H233-R236 PolarHBondContact NE2-NH2 3.41Å; H233-R236 WeakPolarHBondContact O-CB 3.4Å; H233-R236 PolarHBondContact O-N 2.92Å; H233-R236 VanDerWaalsContact O-N 3.08Å; R236-R238 PolarHBondContact O-N 3.35Å; R236-A239 PolarHBondContact O-N 2.91Å; R236-A239 VanDerWaalsContact O-N 3.09Å; R236-E240 WeakPolarHBondContact CD-OE2 3.35Å; R236-E240 IonicContact CZ-OE2 2.79Å; R236-E240 IonicContact NE-OE2 3.35Å; R236-E240 PolarHBondContact NE-OE2 3.34Å; R236-E240 VanDerWaalsContact O-CB 3.3Å; R236-E240 WeakPolarHBondContact O-CB 3.4Å; R236-E240 PolarHBondContact O-N 2.76Å; R236-V314 HydrophobicContact CG-CG1 4.29Å; R236-L317 HydrophobicContact CB-CB 4.12Å; R236-L317 HydrophobicContact CB-CD1 4.46Å; R236-L317 HydrophobicContact CG-CB 4.11Å; R236-N318 WeakPolarHBondContact CG-OD1 3.4Å; R236-N318 PolarHBondContact NH1-OD1 2.66Å; R236-L321 HydrophobicContact CB-CD1 3.76Å; R236-L321 HydrophobicContact CG-CD1 4.03Å
237	D	98.4	Very high	97.8	Very high	42 Å²	42	63.6 Å²	63.6	23%	0.225	30%	0.302	C	S	.	.	H	α-helix	trans	-64.8	-8.2	175.5	-44.9	-32.9	0	0	0	113.6	H233 K234 R241	H233-D237 IonicContact CE1-OD1 2.67Å; H233-D237 PolarHBondContact CE1-OD1 3.25Å; H233-D237 IonicContact CE1-OD2 3.33Å; H233-D237 PolarHBondContact CE1-OD2 2.94Å; H233-D237 IonicContact CG-OD2 2.73Å; H233-D237 IonicContact ND1-OD1 3.76Å; H233-D237 PolarHBondContact ND1-OD1 2.98Å; H233-D237 IonicContact ND1-OD2 3.26Å; H233-D237 PolarHBondContact ND1-OD2 2.99Å; H233-D237 PolarHBondContact O-N 3.32Å; H233-D237 VanDerWaalsContact O-OD2 3.07Å; K234-D237 CarbonylContact O-C 3.55Å; K234-D237 PolarHBondContact O-N 3.1Å; D237-R241 PolarHBondContact O-NE 3.42Å
238	R	98.1	Very high	97.8	Very high	140 Å²	140	64.3 Å²	64.3	53%	0.528	31%	0.307	S	S	.	.	H	α-helix	trans	-93.2	-52.4	166	-63.1	-40.7	179.1	-129.2	11.3	111	K234 L235 R236 E240 R241 I242	K234-R238 WeakPolarHBondContact O-CG 3.38Å; K234-R238 PolarHBondContact O-N 2.82Å; L235-R238 WeakPolarHBondContact O-CA 3.29Å; L235-R238 WeakPolarHBondContact O-CB 3.37Å; L235-R238 PolarHBondContact O-N 2.9Å; L235-R238 VanDerWaalsContact O-N 3.08Å; R236-R238 PolarHBondContact O-N 3.35Å; R238-E240 PolarHBondContact O-N 3.27Å; R238-R241 VanDerWaalsContact CD-NH2 3.25Å; R238-R241 PolarHBondContact O-N 2.97Å; R238-I242 WeakPolarHBondContact O-CG1 3.37Å; R238-I242 PolarHBondContact O-N 2.86Å; R238-I242 VanDerWaalsContact O-N 3.09Å
239	A	98.1	Very high	97.7	Very high	8 Å²	8	66.4 Å²	66.4	7%	0.066	32%	0.318	C	S	.	.	H	α-helix	trans	-56	-48.3	179.9	0	0	0	0	0	112.9	L235 R236 R241 I242 A243 V313 V314 L317	L235-A239 PolarHBondContact O-N 3.39Å; R236-A239 PolarHBondContact O-N 2.91Å; R236-A239 VanDerWaalsContact O-N 3.09Å; A239-R241 VanDerWaalsContact C-N 3.26Å; A239-R241 PolarHBondContact O-N 3.09Å; A239-I242 WeakPolarHBondContact O-CA 3.37Å; A239-I242 WeakPolarHBondContact O-CB 3.5Å; A239-I242 PolarHBondContact O-N 2.8Å; A239-A243 PolarHBondContact O-N 3.41Å; A239-V313 HydrophobicContact CB-CG1 4.13Å; A239-V314 HydrophobicContact CB-CG2 4.02Å; A239-L317 HydrophobicContact CB-CD1 3.65Å
240	E	97.4	Very high	97.7	Very high	95 Å²	95	64.9 Å²	64.9	44%	0.444	31%	0.313	S	S	.	.	H	α-helix	trans	-58.6	-37.2	179.1	-175	171	-153.9	0	0	112.4	R236 R238 S244 V314	R236-E240 WeakPolarHBondContact CD-OE2 3.35Å; R236-E240 IonicContact CZ-OE2 2.79Å; R236-E240 IonicContact NE-OE2 3.35Å; R236-E240 PolarHBondContact NE-OE2 3.34Å; R236-E240 VanDerWaalsContact O-CB 3.3Å; R236-E240 WeakPolarHBondContact O-CB 3.4Å; R236-E240 PolarHBondContact O-N 2.76Å; R238-E240 PolarHBondContact O-N 3.27Å; E240-S244 PolarHBondContact O-N 3.33Å; E240-V314 HydrophobicContact CB-CG1 4.22Å; E240-V314 HydrophobicContact CB-CG2 4.26Å
241	R	98.1	Very high	97.7	Very high	129 Å²	129	64.7 Å²	64.7	49%	0.487	32%	0.319	S	S	.	.	H	α-helix	trans	-78.5	-18.9	174.8	-61.6	-171.6	-53.2	128.8	20.2	113.4	D237 R238 A239 R245	D237-R241 PolarHBondContact O-NE 3.42Å; R238-R241 VanDerWaalsContact CD-NH2 3.25Å; R238-R241 PolarHBondContact O-N 2.97Å; A239-R241 VanDerWaalsContact C-N 3.26Å; A239-R241 PolarHBondContact O-N 3.09Å; R241-R245 WeakPolarHBondContact O-CG 3.38Å; R241-R245 PolarHBondContact O-N 3.45Å; R241-R245 PolarHBondContact O-NH1 3.19Å
242	I	97.1	Very high	97.7	Very high	41 Å²	41	66.4 Å²	66.4	21%	0.21	32%	0.323	C	S	.	.	H	α-helix	trans	-73.8	-48.1	169.9	-55.8	163.7	0	0	0	108.2	R238 A239 S244 R245 A246 E309 F418	R238-I242 WeakPolarHBondContact O-CG1 3.37Å; R238-I242 PolarHBondContact O-N 2.86Å; R238-I242 VanDerWaalsContact O-N 3.09Å; A239-I242 WeakPolarHBondContact O-CA 3.37Å; A239-I242 WeakPolarHBondContact O-CB 3.5Å; A239-I242 PolarHBondContact O-N 2.8Å; I242-S244 VanDerWaalsContact C-N 3.34Å; I242-S244 PolarHBondContact O-N 2.88Å; I242-R245 PolarHBondContact O-N 3.41Å; I242-R245 VanDerWaalsContact O-N 3.07Å; I242-A246 PolarHBondContact O-N 2.97Å; I242-E309 WeakPolarHBondContact CG2-OE2 3.25Å; I242-F418 HydrophobicContact CD1-CE2 3.72Å; I242-F418 HydrophobicContact CD1-CZ 3.9Å
243	A	96.8	Very high	97.7	Very high	6 Å²	6	66 Å²	66	5%	0.05	32%	0.322	C	S	.	.	H	α-helix	trans	-55.9	-45.3	175.1	0	0	0	0	0	112.3	A239 A246 I247 E309	A239-A243 PolarHBondContact O-N 3.41Å; A243-A246 PolarHBondContact O-N 3.11Å; A243-I247 PolarHBondContact O-N 3.49Å; A243-E309 HydrophobicContact CB-CB 3.91Å; A243-E309 PolarHBondContact N-OE2 2.93Å
244	S	96.7	Very high	97.6	Very high	54 Å²	54	66.6 Å²	66.6	38%	0.378	33%	0.326	S	S	.	.	H	α-helix	trans	-54.4	-53.3	172.3	-172.5	0	0	0	0	111.5	E240 I242 A246 I247 D248	E240-S244 PolarHBondContact O-N 3.33Å; I242-S244 VanDerWaalsContact C-N 3.34Å; I242-S244 PolarHBondContact O-N 2.88Å; S244-A246 PolarHBondContact O-N 3.45Å; S244-A246 VanDerWaalsContact O-N 3.16Å; S244-I247 CarbonylContact O-C 3.52Å; S244-I247 WeakPolarHBondContact O-CA 3.48Å; S244-I247 WeakPolarHBondContact O-CB 3.5Å; S244-I247 PolarHBondContact O-N 3.3Å; S244-D248 PolarHBondContact O-N 3.24Å; S244-D248 PolarHBondContact OG-OD2 2.92Å
245	R	96.9	Very high	97.6	Very high	132 Å²	132	64.2 Å²	64.2	50%	0.498	32%	0.32	S	S	.	.	H	α-helix	trans	-62	-27.1	-178.1	-75.4	-166.9	-50.1	-71.2	-5.8	113.7	R241 I242 D248 N249	R241-R245 WeakPolarHBondContact O-CG 3.38Å; R241-R245 PolarHBondContact O-N 3.45Å; R241-R245 PolarHBondContact O-NH1 3.19Å; I242-R245 PolarHBondContact O-N 3.41Å; I242-R245 VanDerWaalsContact O-N 3.07Å; R245-D248 WeakPolarHBondContact CA-OD2 3.46Å; R245-D248 PolarHBondContact N-OD2 2.88Å; R245-N249 WeakPolarHBondContact O-CB 3.43Å; R245-N249 PolarHBondContact O-N 3.46Å
246	A	96.3	Very high	97.6	Very high	11 Å²	11	66.5 Å²	66.5	9%	0.091	33%	0.326	C	S	.	.	H	α-helix	trans	-70.7	-34.3	172.7	0	0	0	0	0	112.1	I242 A243 S244 A250 A302	I242-A246 PolarHBondContact O-N 2.97Å; A243-A246 PolarHBondContact O-N 3.11Å; S244-A246 PolarHBondContact O-N 3.45Å; S244-A246 VanDerWaalsContact O-N 3.16Å; A246-A250 PolarHBondContact O-N 3.25Å; A246-A250 VanDerWaalsContact O-N 3.12Å; A246-A302 CarbonylContact O-C 3.55Å
247	I	96.4	Very high	97.5	Very high	87 Å²	87	64.6 Å²	64.6	45%	0.446	32%	0.321	S	S	.	.	H	α-helix	trans	-72.1	-42.2	171.9	-61	167.1	0	0	0	110.8	A243 S244 A250 A251	A243-I247 PolarHBondContact O-N 3.49Å; S244-I247 CarbonylContact O-C 3.52Å; S244-I247 WeakPolarHBondContact O-CA 3.48Å; S244-I247 WeakPolarHBondContact O-CB 3.5Å; S244-I247 PolarHBondContact O-N 3.3Å; I247-A250 VanDerWaalsContact O-CB 3.29Å; I247-A250 WeakPolarHBondContact O-CB 3.25Å; I247-A250 PolarHBondContact O-N 3.14Å; I247-A250 VanDerWaalsContact O-N 3.12Å; I247-A251 PolarHBondContact O-N 3.05Å
248	D	97.6	Very high	97.5	Very high	79 Å²	79	68 Å²	68	42%	0.422	33%	0.334	S	S	.	.	H	α-helix	trans	-60.1	-49.7	176.9	-55.6	-41.7	0	0	0	110.3	S244 R245 A250 A251 D252	S244-D248 PolarHBondContact O-N 3.24Å; S244-D248 PolarHBondContact OG-OD2 2.92Å; R245-D248 WeakPolarHBondContact CA-OD2 3.46Å; R245-D248 PolarHBondContact N-OD2 2.88Å; D248-A250 VanDerWaalsContact C-N 3.25Å; D248-A250 PolarHBondContact O-N 2.9Å; D248-A251 WeakPolarHBondContact O-CB 3.47Å; D248-A251 PolarHBondContact O-N 3.4Å; D248-D252 PolarHBondContact O-N 3.02Å
249	N	97.1	Very high	97.4	Very high	72 Å²	72	66.7 Å²	66.7	39%	0.385	33%	0.333	S	S	.	.	H	α-helix	trans	-59.2	-32.3	173.6	175	69.3	0	0	0	113	R245 L253 A302	R245-N249 WeakPolarHBondContact O-CB 3.43Å; R245-N249 PolarHBondContact O-N 3.46Å; N249-L253 WeakPolarHBondContact ND2-CD1 3.28Å; N249-L253 WeakPolarHBondContact O-CB 3.32Å; N249-L253 WeakPolarHBondContact O-CD1 3.21Å; N249-L253 VanDerWaalsContact O-CG 3.23Å; N249-L253 WeakPolarHBondContact O-CG 3.31Å; N249-L253 PolarHBondContact O-N 3.35Å; N249-A302 WeakPolarHBondContact ND2-CB 3.38Å
250	A	98.2	Very high	97.3	Very high	8 Å²	8	67.3 Å²	67.3	7%	0.066	34%	0.335	C	S	.	.	H	α-helix	trans	-66.8	-39.5	173.4	0	0	0	0	0	112.3	A246 I247 D248 L254 A299 A302 A303	A246-A250 PolarHBondContact O-N 3.25Å; A246-A250 VanDerWaalsContact O-N 3.12Å; I247-A250 VanDerWaalsContact O-CB 3.29Å; I247-A250 WeakPolarHBondContact O-CB 3.25Å; I247-A250 PolarHBondContact O-N 3.14Å; I247-A250 VanDerWaalsContact O-N 3.12Å; D248-A250 VanDerWaalsContact C-N 3.25Å; D248-A250 PolarHBondContact O-N 2.9Å; A250-L254 VanDerWaalsContact O-CB 3.31Å; A250-L254 WeakPolarHBondContact O-CB 3.41Å; A250-L254 PolarHBondContact O-N 3.48Å; A250-A299 VanDerWaalsContact CB-O 3.29Å; A250-A299 WeakPolarHBondContact CB-O 3.36Å; A250-A299 VanDerWaalsContact O-CB 3.22Å; A250-A299 WeakPolarHBondContact O-CB 3.43Å; A250-A302 HydrophobicContact CB-CB 3.7Å; A250-A303 HydrophobicContact CB-CB 3.81Å
251	A	98.2	Very high	97.2	Very high	48 Å²	48	64.4 Å²	64.4	40%	0.397	33%	0.326	S	S	.	.	H	α-helix	trans	-65	-45.3	174.9	0	0	0	0	0	111.2	I247 D248 L254 I255	I247-A251 PolarHBondContact O-N 3.05Å; D248-A251 WeakPolarHBondContact O-CB 3.47Å; D248-A251 PolarHBondContact O-N 3.4Å; A251-L254 PolarHBondContact O-N 2.95Å; A251-I255 VanDerWaalsContact O-CG1 3.3Å; A251-I255 WeakPolarHBondContact O-CG1 3.12Å; A251-I255 PolarHBondContact O-N 3.2Å
252	D	98.4	Very high	97	Very high	108 Å²	108	60.8 Å²	60.8	58%	0.578	32%	0.323	S	S	*	.	H	α-helix	trans	-61	-47.4	177.7	-70.8	-24.8	0	0	0	112.2	D248 L254 I255 F256	D248-D252 PolarHBondContact O-N 3.02Å; D252-L254 VanDerWaalsContact C-N 3.31Å; D252-L254 PolarHBondContact O-N 3Å; D252-I255 PolarHBondContact O-N 3.47Å; D252-F256 WeakPolarHBondContact O-CB 3.34Å; D252-F256 PolarHBondContact O-N 3.31Å
253	L	98.1	Very high	96.8	Very high	17 Å²	17	62.6 Å²	62.6	9%	0.089	33%	0.332	C	S	.	.	H	α-helix	trans	-59.9	-40.3	175.7	-75.2	164.8	0	0	0	112.1	N249 G257 F295 L298 A299 A302 W433	N249-L253 WeakPolarHBondContact ND2-CD1 3.28Å; N249-L253 WeakPolarHBondContact O-CB 3.32Å; N249-L253 WeakPolarHBondContact O-CD1 3.21Å; N249-L253 VanDerWaalsContact O-CG 3.23Å; N249-L253 WeakPolarHBondContact O-CG 3.31Å; N249-L253 PolarHBondContact O-N 3.35Å; L253-G257 PolarHBondContact O-N 2.61Å; L253-F295 HydrophobicContact CD2-CD1 3.91Å; L253-F295 HydrophobicContact CD2-CE1 4Å; L253-L298 HydrophobicContact CD1-CB 4.1Å; L253-L298 HydrophobicContact CD2-CB 4.23Å; L253-A299 HydrophobicContact CB-CB 4.01Å; L253-A302 HydrophobicContact CD1-CB 4.11Å; L253-W433 HydrophobicContact CD2-CH2 4.41Å; L253-W433 HydrophobicContact CD2-CZ2 4.27Å
254	L	98.1	Very high	96.4	Very high	70 Å²	70	62.7 Å²	62.7	37%	0.366	33%	0.334	S	S	.	.	H	α-helix	trans	-69.7	-35.5	177.9	-177.3	61.4	0	0	0	112.4	A250 A251 D252 K258 A296 A299	A250-L254 VanDerWaalsContact O-CB 3.31Å; A250-L254 WeakPolarHBondContact O-CB 3.41Å; A250-L254 PolarHBondContact O-N 3.48Å; A251-L254 PolarHBondContact O-N 2.95Å; D252-L254 VanDerWaalsContact C-N 3.31Å; D252-L254 PolarHBondContact O-N 3Å; L254-K258 VanDerWaalsContact O-CG 3.3Å; L254-K258 WeakPolarHBondContact O-CG 3.24Å; L254-K258 PolarHBondContact O-N 3.49Å; L254-A296 HydrophobicContact CD1-CB 4.25Å; L254-A299 HydrophobicContact CB-CB 3.77Å
255	I	98.2	Very high	96.2	Very high	87 Å²	87	62.5 Å²	62.5	45%	0.446	33%	0.333	S	S	.	.	H	α-helix	trans	-68.8	-47.8	174.4	-70.1	162.1	0	0	0	109.7	A251 D252 G257 K258 E259	A251-I255 VanDerWaalsContact O-CG1 3.3Å; A251-I255 WeakPolarHBondContact O-CG1 3.12Å; A251-I255 PolarHBondContact O-N 3.2Å; D252-I255 PolarHBondContact O-N 3.47Å; I255-G257 VanDerWaalsContact C-N 3.29Å; I255-G257 PolarHBondContact O-N 3.23Å; I255-K258 WeakPolarHBondContact O-CA 3.26Å; I255-K258 WeakPolarHBondContact O-CB 3.26Å; I255-K258 PolarHBondContact O-N 3.22Å; I255-E259 PolarHBondContact O-N 2.98Å
256	F	97.7	Very high	95.7	Very high	118 Å²	118	59.1 Å²	59.1	52%	0.518	33%	0.325	S	S	.	.	H	α-helix	trans	-54.9	-45.2	176.2	-165.6	-84.5	0	0	0	111.7	D252 K258 E259 L260 F295	D252-F256 WeakPolarHBondContact O-CB 3.34Å; D252-F256 PolarHBondContact O-N 3.31Å; F256-K258 VanDerWaalsContact C-N 3.34Å; F256-K258 PolarHBondContact O-N 3.02Å; F256-E259 PolarHBondContact O-N 3.39Å; F256-L260 HydrophobicContact CD1-CD1 3.94Å; F256-L260 HydrophobicContact CD1-CG 4.09Å; F256-L260 HydrophobicContact CE1-CD1 3.87Å; F256-L260 HydrophobicContact CE1-CD2 4.06Å; F256-L260 HydrophobicContact CE1-CG 4.02Å; F256-L260 WeakPolarHBondContact O-CG 3.25Å; F256-L260 PolarHBondContact O-N 2.98Å; F256-L260 VanDerWaalsContact O-N 3.07Å; F256-F295 HydrophobicContact CB-CD1 4.23Å; F256-F295 HydrophobicContact CB-CE1 4.43Å; F256-F295 AromaticContact CD1-CD1 3.62Å; F256-F295 HydrophobicContact CD1-CD1 3.62Å; F256-F295 HydrophobicContact CD1-CD2 4.36Å; F256-F295 AromaticContact CD1-CE1 3.29Å; F256-F295 HydrophobicContact CD1-CE1 3.29Å; F256-F295 HydrophobicContact CD1-CE2 4.09Å; F256-F295 HydrophobicContact CD1-CG 4.15Å; F256-F295 AromaticContact CD1-CZ 3.56Å; F256-F295 HydrophobicContact CD1-CZ 3.56Å; F256-F295 HydrophobicContact CE1-CD1 4.43Å; F256-F295 AromaticContact CE1-CE1 3.74Å; F256-F295 HydrophobicContact CE1-CE1 3.74Å; F256-F295 HydrophobicContact CE1-CE2 4.06Å; F256-F295 AromaticContact CE1-CZ 3.52Å; F256-F295 HydrophobicContact CE1-CZ 3.52Å; F256-F295 HydrophobicContact CG-CD1 4.28Å; F256-F295 HydrophobicContact CG-CE1 4.06Å
257	G	96.8	Very high	95.2	Very high	4 Å²	4	65.1 Å²	65.1	4%	0.041	36%	0.36	C	S	.	.	H	α-helix	trans	-59.4	-38.8	174	0	0	0	0	0	113.9	L253 I255 L260 S261 S292 F295	L253-G257 PolarHBondContact O-N 2.61Å; I255-G257 VanDerWaalsContact C-N 3.29Å; I255-G257 PolarHBondContact O-N 3.23Å; G257-L260 PolarHBondContact O-N 3.35Å; G257-S261 PolarHBondContact O-N 3.01Å; G257-S261 VanDerWaalsContact O-N 3.1Å; G257-S292 WeakPolarHBondContact O-CB 3.41Å; G257-F295 VanDerWaalsContact CA-CB 3.49Å
258	K	96.9	Very high	94.7	Very high	115 Å²	115	65.5 Å²	65.5	50%	0.5	37%	0.367	S	S	.	.	H	α-helix	trans	-65.3	-43	175.7	-72.6	163.8	-176.5	169.2	0	111.9	L254 I255 F256 L260 S261 A262	L254-K258 VanDerWaalsContact O-CG 3.3Å; L254-K258 WeakPolarHBondContact O-CG 3.24Å; L254-K258 PolarHBondContact O-N 3.49Å; I255-K258 WeakPolarHBondContact O-CA 3.26Å; I255-K258 WeakPolarHBondContact O-CB 3.26Å; I255-K258 PolarHBondContact O-N 3.22Å; F256-K258 VanDerWaalsContact C-N 3.34Å; F256-K258 PolarHBondContact O-N 3.02Å; K258-L260 PolarHBondContact O-N 3.23Å; K258-S261 CarbonylContact O-C 3.54Å; K258-S261 WeakPolarHBondContact O-CA 3.41Å; K258-S261 WeakPolarHBondContact O-CB 3.44Å; K258-S261 PolarHBondContact O-N 2.9Å; K258-S261 VanDerWaalsContact O-N 3.09Å; K258-A262 PolarHBondContact O-N 3.22Å
259	E	97.3	Very high	93.8	Very high	111 Å²	111	67 Å²	67	52%	0.519	38%	0.381	S	S	.	.	H	α-helix	trans	-64.8	-39.6	177.9	-60.7	-47.9	129.2	0	0	112.1	I255 F256 S261 A262 I263	I255-E259 PolarHBondContact O-N 2.98Å; F256-E259 PolarHBondContact O-N 3.39Å; E259-S261 VanDerWaalsContact C-N 3.27Å; E259-S261 PolarHBondContact O-N 3.41Å; E259-A262 PolarHBondContact O-N 3.05Å; E259-I263 WeakPolarHBondContact O-CG1 3.28Å; E259-I263 PolarHBondContact O-N 3.32Å
260	L	94.4	Very high	92.9	Very high	21 Å²	21	67 Å²	67	11%	0.11	38%	0.38	C	S	.	.	H	α-helix	trans	-57.9	-40.9	170.2	-64.4	178.3	0	0	0	112	F256 G257 K258 G264 L288 L291 F295	F256-L260 HydrophobicContact CD1-CD1 3.94Å; F256-L260 HydrophobicContact CD1-CG 4.09Å; F256-L260 HydrophobicContact CE1-CD1 3.87Å; F256-L260 HydrophobicContact CE1-CD2 4.06Å; F256-L260 HydrophobicContact CE1-CG 4.02Å; F256-L260 WeakPolarHBondContact O-CG 3.25Å; F256-L260 PolarHBondContact O-N 2.98Å; F256-L260 VanDerWaalsContact O-N 3.07Å; G257-L260 PolarHBondContact O-N 3.35Å; K258-L260 PolarHBondContact O-N 3.23Å; L260-G264 PolarHBondContact O-N 2.99Å; L260-L288 HydrophobicContact CD2-CD2 3.82Å; L260-L291 HydrophobicContact CD1-CB 4.04Å; L260-F295 HydrophobicContact CD1-CD2 3.58Å; L260-F295 HydrophobicContact CD1-CE2 3.7Å; L260-F295 HydrophobicContact CD1-CG 4.32Å
261	S	95.2	Very high	92.2	Very high	35 Å²	35	69.6 Å²	69.6	25%	0.245	40%	0.397	C	S	.	.	H	α-helix	trans	-69	-34.8	177	-158.8	0	0	0	0	112.8	G257 K258 E259 G264 S265	G257-S261 PolarHBondContact O-N 3.01Å; G257-S261 VanDerWaalsContact O-N 3.1Å; K258-S261 CarbonylContact O-C 3.54Å; K258-S261 WeakPolarHBondContact O-CA 3.41Å; K258-S261 WeakPolarHBondContact O-CB 3.44Å; K258-S261 PolarHBondContact O-N 2.9Å; K258-S261 VanDerWaalsContact O-N 3.09Å; E259-S261 VanDerWaalsContact C-N 3.27Å; E259-S261 PolarHBondContact O-N 3.41Å; S261-G264 CarbonylContact O-C 3.56Å; S261-S265 WeakPolarHBondContact O-CB 3.41Å; S261-S265 PolarHBondContact O-N 3.18Å; S261-S265 PolarHBondContact O-OG 3.41Å
262	A	95.7	Very high	91	Very high	52 Å²	52	71.8 Å²	71.8	43%	0.43	41%	0.409	S	S	.	.	H	α-helix	trans	-66.8	-52	176.3	0	0	0	0	0	111	K258 E259 G264 S265 D266	K258-A262 PolarHBondContact O-N 3.22Å; E259-A262 PolarHBondContact O-N 3.05Å; A262-G264 VanDerWaalsContact C-N 3.28Å; A262-G264 PolarHBondContact O-N 3.02Å; A262-S265 CarbonylContact O-C 3.57Å; A262-S265 PolarHBondContact O-N 3.23Å; A262-D266 PolarHBondContact O-N 3.09Å
263	I	92.2	Very high	89.9	Confident	79 Å²	79	76.1 Å²	76.1	41%	0.405	42%	0.418	S	S	.	.	H	α-helix	trans	-57.7	-43.5	174.3	-60.9	162.5	0	0	0	110.3	E259 S265 D266 W281 L288	E259-I263 WeakPolarHBondContact O-CG1 3.28Å; E259-I263 PolarHBondContact O-N 3.32Å; I263-S265 PolarHBondContact O-N 3.37Å; I263-D266 PolarHBondContact O-N 3.16Å; I263-W281 HydrophobicContact CG2-CH2 4.07Å; I263-L288 HydrophobicContact CB-CD1 4.49Å; I263-L288 HydrophobicContact CG2-CD1 3.74Å
264	G	89.1	Confident	88.6	Confident	9 Å²	9	76.4 Å²	76.4	9%	0.093	42%	0.422	C	S	.	.	T	Hydrogen-bonded Turn	trans	-72.6	-7.1	177.6	0	0	0	0	0	115.7	L260 S261 A262 K285	L260-G264 PolarHBondContact O-N 2.99Å; S261-G264 CarbonylContact O-C 3.56Å; A262-G264 VanDerWaalsContact C-N 3.28Å; A262-G264 PolarHBondContact O-N 3.02Å; G264-K285 WeakPolarHBondContact CA-O 3.39Å
265	S	91.1	Very high	87	Confident	49 Å²	49	75.7 Å²	75.7	34%	0.343	43%	0.426	S	S	.	.	T	Hydrogen-bonded Turn	trans	-115	-2.7	178	-57	0	0	0	0	113.7	S261 A262 I263 T267 K289	S261-S265 WeakPolarHBondContact O-CB 3.41Å; S261-S265 PolarHBondContact O-N 3.18Å; S261-S265 PolarHBondContact O-OG 3.41Å; A262-S265 CarbonylContact O-C 3.57Å; A262-S265 PolarHBondContact O-N 3.23Å; I263-S265 PolarHBondContact O-N 3.37Å; S265-T267 PolarHBondContact O-N 2.85Å; S265-K289 WeakPolarHBondContact OG-CD 3.26Å; S265-K289 WeakPolarHBondContact OG-CE 3.26Å; S265-K289 PolarHBondContact OG-NZ 2.86Å
266	D	87.7	Confident	85.1	Confident	62 Å²	62	78.1 Å²	78.1	33%	0.332	44%	0.44	S	S	.	.			trans	-56.6	122.5	174.5	165.9	43.7	0	0	0	110.9	A262 I263 T268 K285	A262-D266 PolarHBondContact O-N 3.09Å; I263-D266 PolarHBondContact O-N 3.16Å; D266-T268 WeakPolarHBondContact OD1-CB 3.42Å; D266-T268 PolarHBondContact OD1-N 2.85Å; D266-T268 PolarHBondContact OD1-OG1 3.42Å; D266-K285 PolarHBondContact O-NZ 2.76Å; D266-K285 IonicContact OD2-NZ 2.67Å; D266-K285 PolarHBondContact OD2-NZ 3.24Å
267	T	85.4	Confident	83.2	Confident	137 Å²	137	79.7 Å²	79.7	84%	0.84	45%	0.454	S	S	*	.			trans	-96.4	4.9	178.2	54.4	0	0	0	0	113.5	S265	S265-T267 PolarHBondContact O-N 2.85Å
268	T	86	Confident	81.2	Confident	94 Å²	94	81.5 Å²	81.5	58%	0.577	47%	0.465	S	S	*	.	P	Polyproline II helix	trans	-56.3	124.1	178.1	-56.3	0	0	0	0	110.2	D266	D266-T268 WeakPolarHBondContact OD1-CB 3.42Å; D266-T268 PolarHBondContact OD1-N 2.85Å; D266-T268 PolarHBondContact OD1-OG1 3.42Å
269	P	79	Confident	79.6	Confident	111 Å²	111	80.6 Å²	80.6	72%	0.721	47%	0.473	S	S	*	.	P	Polyproline II helix	trans	-69.2	141.5	-178	28.5	-34.9	0	0	0	110.6
270	L	78.1	Confident	78.4	Confident	71 Å²	71	78.3 Å²	78.3	37%	0.372	47%	0.467	S	S	.	.	P	Polyproline II helix	trans	-73.5	134.2	178.9	-147	63.8	0	0	0	110	A274 W281	L270-A274 HydrophobicContact CD2-CB 4.16Å; L270-A274 HydrophobicContact CG-CB 3.97Å; L270-W281 VanDerWaalsContact CD1-CD1 3.46Å; L270-W281 HydrophobicContact CD1-CG 4.48Å
271	P	81.7	Confident	77.6	Confident	63 Å²	63	81.6 Å²	81.6	41%	0.409	48%	0.478	S	S	.	.	P	Polyproline II helix	trans	-55.5	143.6	173.5	-26.8	35.4	0	0	0	111.7	W273 A274 A275	P271-W273 VanDerWaalsContact C-N 3.28Å; P271-W273 HydrophobicContact CB-CD2 4.48Å; P271-W273 HydrophobicContact CB-CG 4.4Å; P271-W273 HydrophobicContact CB-CZ2 4.42Å; P271-W273 PolarHBondContact O-N 3.06Å; P271-A274 WeakPolarHBondContact O-CA 3.44Å; P271-A274 WeakPolarHBondContact O-CB 3.16Å; P271-A274 PolarHBondContact O-N 3.19Å; P271-A275 PolarHBondContact O-N 2.73Å
272	S	74.6	Confident	76.9	Confident	95 Å²	95	82.1 Å²	82.1	66%	0.664	49%	0.489	S	S	*	.	H	α-helix	trans	-53.5	-43.1	-175.2	51.3	0	0	0	0	113.2	A274 A275 L276	S272-A274 PolarHBondContact O-N 2.73Å; S272-A275 PolarHBondContact O-N 2.96Å; S272-A275 VanDerWaalsContact O-N 3.16Å; S272-L276 WeakPolarHBondContact O-CD1 3.47Å; S272-L276 PolarHBondContact O-N 2.78Å
273	W	75.4	Confident	76.1	Confident	199 Å²	199	83.2 Å²	83.2	75%	0.754	49%	0.494	S	S	*	.	H	α-helix	trans	-62.1	-27.7	177.2	64.2	-100	0	0	0	114	P271	P271-W273 VanDerWaalsContact C-N 3.28Å; P271-W273 HydrophobicContact CB-CD2 4.48Å; P271-W273 HydrophobicContact CB-CG 4.4Å; P271-W273 HydrophobicContact CB-CZ2 4.42Å; P271-W273 PolarHBondContact O-N 3.06Å
274	A	69.5	Low	75.7	Confident	22 Å²	22	82.1 Å²	82.1	18%	0.182	49%	0.488	C	S	.	.	H	α-helix	trans	-86.5	-28.6	176.5	0	0	0	0	0	112.1	L270 P271 S272 L276	L270-A274 HydrophobicContact CD2-CB 4.16Å; L270-A274 HydrophobicContact CG-CB 3.97Å; P271-A274 WeakPolarHBondContact O-CA 3.44Å; P271-A274 WeakPolarHBondContact O-CB 3.16Å; P271-A274 PolarHBondContact O-N 3.19Å; S272-A274 PolarHBondContact O-N 2.73Å; A274-L276 VanDerWaalsContact C-N 3.32Å; A274-L276 PolarHBondContact O-N 2.94Å
275	A	65.1	Low	75.6	Confident	55 Å²	55	82.9 Å²	82.9	46%	0.455	49%	0.489	S	S	.	.	H	α-helix	trans	-69	-25.5	177.3	0	0	0	0	0	113.6	P271 S272 N277	P271-A275 PolarHBondContact O-N 2.73Å; S272-A275 PolarHBondContact O-N 2.96Å; S272-A275 VanDerWaalsContact O-N 3.16Å; A275-N277 PolarHBondContact O-N 3.35Å; A275-N277 VanDerWaalsContact O-N 3.15Å
276	L	59	Low	75.3	Confident	139 Å²	139	87.9 Å²	87.9	73%	0.728	51%	0.507	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.8	-31	180	-99.6	71.5	0	0	0	114	S272 A274	S272-L276 WeakPolarHBondContact O-CD1 3.47Å; S272-L276 PolarHBondContact O-N 2.78Å; A274-L276 VanDerWaalsContact C-N 3.32Å; A274-L276 PolarHBondContact O-N 2.94Å
277	N	56.4	Low	75.1	Confident	151 Å²	151	86.2 Å²	86.2	81%	0.807	50%	0.502	S	S	*	.	T	Hydrogen-bonded Turn	trans	-123.6	3.5	-168.1	-65	-15.6	0	0	0	114.5	A275	A275-N277 PolarHBondContact O-N 3.35Å; A275-N277 VanDerWaalsContact O-N 3.15Å
278	S	56.2	Low	75.3	Confident	41 Å²	41	80.9 Å²	80.9	29%	0.287	47%	0.468	S	S	.	.			trans	-145.3	92.4	-166.9	-172.4	0	0	0	0	114.8	T280 W281	S278-T280 VanDerWaalsContact C-N 3.31Å; S278-T280 PolarHBondContact OG-OG1 3.13Å; S278-W281 PolarHBondContact OG-N 3.24Å
279	S	62.5	Low	75.4	Confident	96 Å²	96	81.2 Å²	81.2	67%	0.671	46%	0.461	S	S	*	.	S	Bend	trans	-78.4	-18.6	155.5	54.8	0	0	0	0	112.2	W281 G282	S279-W281 VanDerWaalsContact C-N 3.32Å; S279-W281 PolarHBondContact O-N 2.8Å; S279-G282 PolarHBondContact O-N 2.91Å
280	T	71.8	Confident	75.8	Confident	64 Å²	64	77.9 Å²	77.9	39%	0.393	45%	0.448	S	S	.	.	H	α-helix	trans	-61.5	-31.6	-177.1	23.6	0	0	0	0	113.7	S278 G282 S283 L284	S278-T280 VanDerWaalsContact C-N 3.31Å; S278-T280 PolarHBondContact OG-OG1 3.13Å; T280-G282 PolarHBondContact O-N 2.89Å; T280-S283 PolarHBondContact O-N 3.46Å; T280-L284 VanDerWaalsContact O-CB 3.3Å; T280-L284 WeakPolarHBondContact O-CB 3.38Å; T280-L284 PolarHBondContact O-N 3.12Å
281	W	78.8	Confident	76.4	Confident	89 Å²	89	75.1 Å²	75.1	34%	0.337	43%	0.433	S	S	.	.	H	α-helix	trans	-66.2	-35.8	178	-176.4	-129	0	0	0	113.1	I263 L270 S278 S279 L284 K285	I263-W281 HydrophobicContact CG2-CH2 4.07Å; L270-W281 VanDerWaalsContact CD1-CD1 3.46Å; L270-W281 HydrophobicContact CD1-CG 4.48Å; S278-W281 PolarHBondContact OG-N 3.24Å; S279-W281 VanDerWaalsContact C-N 3.32Å; S279-W281 PolarHBondContact O-N 2.8Å; W281-L284 HydrophobicContact CE3-CB 4.22Å; W281-L284 HydrophobicContact CE3-CD2 3.88Å; W281-L284 HydrophobicContact CE3-CG 4.21Å; W281-L284 HydrophobicContact CZ3-CD2 3.84Å; W281-L284 HydrophobicContact CZ3-CG 4.15Å; W281-L284 PolarHBondContact O-N 2.91Å; W281-K285 HydrophobicContact CD2-CG 4.47Å; W281-K285 VanDerWaalsContact CE2-CE 3.48Å; W281-K285 HydrophobicContact CZ2-CG 4.28Å; W281-K285 PolarHBondContact O-N 3.33Å
282	G	79.9	Confident	77	Confident	46 Å²	46	73 Å²	73	47%	0.474	42%	0.42	S	S	.	.	H	α-helix	trans	-65	-47.7	175.4	0	0	0	0	0	112	S279 T280 L284 K285 Q286	S279-G282 PolarHBondContact O-N 2.91Å; T280-G282 PolarHBondContact O-N 2.89Å; G282-L284 VanDerWaalsContact C-N 3.3Å; G282-L284 PolarHBondContact O-N 3.42Å; G282-K285 PolarHBondContact O-N 2.72Å; G282-Q286 PolarHBondContact O-N 2.83Å; G282-Q286 VanDerWaalsContact O-N 3.1Å
283	S	79.4	Confident	77.8	Confident	75 Å²	75	73 Å²	73	52%	0.524	42%	0.416	S	S	.	.	H	α-helix	trans	-59.5	-40.2	173.8	-52.6	0	0	0	0	112	T280 Q286 A287	T280-S283 PolarHBondContact O-N 3.46Å; S283-Q286 PolarHBondContact O-N 3.05Å; S283-A287 WeakPolarHBondContact O-CB 3.41Å; S283-A287 PolarHBondContact O-N 3.39Å
284	L	83.1	Confident	78.7	Confident	56 Å²	56	65.1 Å²	65.1	29%	0.293	39%	0.387	S	S	.	.	H	α-helix	trans	-66	-43.5	177.6	-176.7	52.6	0	0	0	111.8	T280 W281 G282 Q286 A287 L288 L443	T280-L284 VanDerWaalsContact O-CB 3.3Å; T280-L284 WeakPolarHBondContact O-CB 3.38Å; T280-L284 PolarHBondContact O-N 3.12Å; W281-L284 HydrophobicContact CE3-CB 4.22Å; W281-L284 HydrophobicContact CE3-CD2 3.88Å; W281-L284 HydrophobicContact CE3-CG 4.21Å; W281-L284 HydrophobicContact CZ3-CD2 3.84Å; W281-L284 HydrophobicContact CZ3-CG 4.15Å; W281-L284 PolarHBondContact O-N 2.91Å; G282-L284 VanDerWaalsContact C-N 3.3Å; G282-L284 PolarHBondContact O-N 3.42Å; L284-Q286 PolarHBondContact O-N 3.17Å; L284-A287 PolarHBondContact O-N 2.92Å; L284-L288 HydrophobicContact CD1-CD1 4.09Å; L284-L288 HydrophobicContact CD1-CD2 4.39Å; L284-L288 HydrophobicContact CD1-CG 3.93Å; L284-L288 HydrophobicContact CG-CD1 3.94Å; L284-L288 HydrophobicContact CG-CG 4.31Å; L284-L288 WeakPolarHBondContact O-CB 3.39Å; L284-L288 WeakPolarHBondContact O-CG 3.39Å; L284-L288 PolarHBondContact O-N 3.11Å; L284-L443 HydrophobicContact CD1-CB 4.44Å; L284-L443 HydrophobicContact CD1-CD2 3.53Å
285	K	86.3	Confident	79.9	Confident	25 Å²	25	65.1 Å²	65.1	11%	0.109	38%	0.383	C	S	.	.	H	α-helix	trans	-56.5	-48.8	172.3	-73.7	-167.3	-176.5	-176.6	0	111.7	G264 D266 W281 G282 A287 L288 K289	G264-K285 WeakPolarHBondContact CA-O 3.39Å; D266-K285 PolarHBondContact O-NZ 2.76Å; D266-K285 IonicContact OD2-NZ 2.67Å; D266-K285 PolarHBondContact OD2-NZ 3.24Å; W281-K285 HydrophobicContact CD2-CG 4.47Å; W281-K285 VanDerWaalsContact CE2-CE 3.48Å; W281-K285 HydrophobicContact CZ2-CG 4.28Å; W281-K285 PolarHBondContact O-N 3.33Å; G282-K285 PolarHBondContact O-N 2.72Å; K285-A287 VanDerWaalsContact C-N 3.33Å; K285-A287 PolarHBondContact O-N 2.66Å; K285-L288 PolarHBondContact O-N 2.93Å; K285-K289 WeakPolarHBondContact O-CB 3.37Å; K285-K289 PolarHBondContact O-N 3.4Å
286	Q	84.4	Confident	81.4	Confident	155 Å²	155	64.6 Å²	64.6	72%	0.724	38%	0.379	S	S	*	.	H	α-helix	trans	-61	-41.7	179.1	-175.8	176.8	-2.8	0	0	112.1	G282 S283 L284 K289 G290	G282-Q286 PolarHBondContact O-N 2.83Å; G282-Q286 VanDerWaalsContact O-N 3.1Å; S283-Q286 PolarHBondContact O-N 3.05Å; L284-Q286 PolarHBondContact O-N 3.17Å; Q286-K289 PolarHBondContact O-N 3.16Å; Q286-G290 PolarHBondContact O-N 3.04Å
287	A	85.3	Confident	83.2	Confident	26 Å²	26	61.4 Å²	61.4	22%	0.215	36%	0.362	C	S	.	.	H	α-helix	trans	-69.2	-45	178.7	0	0	0	0	0	112.4	S283 L284 K285 K289 G290 L291 L443	S283-A287 WeakPolarHBondContact O-CB 3.41Å; S283-A287 PolarHBondContact O-N 3.39Å; L284-A287 PolarHBondContact O-N 2.92Å; K285-A287 VanDerWaalsContact C-N 3.33Å; K285-A287 PolarHBondContact O-N 2.66Å; A287-K289 VanDerWaalsContact C-N 3.27Å; A287-K289 PolarHBondContact O-N 2.97Å; A287-G290 WeakPolarHBondContact O-CA 3.45Å; A287-G290 PolarHBondContact O-N 3.21Å; A287-L291 WeakPolarHBondContact O-CG 3.49Å; A287-L291 PolarHBondContact O-N 3.49Å; A287-L443 HydrophobicContact CB-CD2 3.46Å; A287-L443 VanDerWaalsContact CB-CD2 3.46Å
288	L	89	Confident	85.1	Confident	26 Å²	26	54.2 Å²	54.2	14%	0.136	32%	0.323	C	S	.	.	H	α-helix	trans	-55.6	-43.5	173.7	-70.1	167	0	0	0	111.4	L260 I263 L284 K285 G290 L291 S292	L260-L288 HydrophobicContact CD2-CD2 3.82Å; I263-L288 HydrophobicContact CB-CD1 4.49Å; I263-L288 HydrophobicContact CG2-CD1 3.74Å; L284-L288 HydrophobicContact CD1-CD1 4.09Å; L284-L288 HydrophobicContact CD1-CD2 4.39Å; L284-L288 HydrophobicContact CD1-CG 3.93Å; L284-L288 HydrophobicContact CG-CD1 3.94Å; L284-L288 HydrophobicContact CG-CG 4.31Å; L284-L288 WeakPolarHBondContact O-CB 3.39Å; L284-L288 WeakPolarHBondContact O-CG 3.39Å; L284-L288 PolarHBondContact O-N 3.11Å; K285-L288 PolarHBondContact O-N 2.93Å; L288-G290 VanDerWaalsContact C-N 3.34Å; L288-G290 PolarHBondContact O-N 3.44Å; L288-L291 PolarHBondContact O-N 2.92Å; L288-S292 PolarHBondContact O-N 3.18Å
289	K	88.4	Confident	87.1	Confident	100 Å²	100	52.5 Å²	52.5	44%	0.435	31%	0.312	S	S	.	.	H	α-helix	trans	-60.8	-40.4	173.7	-170.4	166.2	-175.4	152.9	0	112.5	S265 K285 Q286 A287 S292	S265-K289 WeakPolarHBondContact OG-CD 3.26Å; S265-K289 WeakPolarHBondContact OG-CE 3.26Å; S265-K289 PolarHBondContact OG-NZ 2.86Å; K285-K289 WeakPolarHBondContact O-CB 3.37Å; K285-K289 PolarHBondContact O-N 3.4Å; Q286-K289 PolarHBondContact O-N 3.16Å; A287-K289 VanDerWaalsContact C-N 3.27Å; A287-K289 PolarHBondContact O-N 2.97Å; K289-S292 WeakPolarHBondContact O-CB 3.3Å; K289-S292 PolarHBondContact O-N 3.44Å; K289-S292 PolarHBondContact O-OG 3.44Å
290	G	87.1	Confident	88.8	Confident	42 Å²	42	51.2 Å²	51.2	43%	0.433	30%	0.298	S	S	.	.	H	α-helix	trans	-61.4	-44.3	173.5	0	0	0	0	0	113.6	Q286 A287 L288 S292 V293	Q286-G290 PolarHBondContact O-N 3.04Å; A287-G290 WeakPolarHBondContact O-CA 3.45Å; A287-G290 PolarHBondContact O-N 3.21Å; L288-G290 VanDerWaalsContact C-N 3.34Å; L288-G290 PolarHBondContact O-N 3.44Å; G290-S292 PolarHBondContact O-N 2.93Å; G290-V293 PolarHBondContact O-N 3.4Å
291	L	90.3	Very high	90	Very high	12 Å²	12	50.3 Å²	50.3	6%	0.063	29%	0.288	C	S	.	.	H	α-helix	trans	-62.1	-26.3	179.7	-61.7	169.5	0	0	0	113	L260 A287 L288 V293 E294 F295 L436 K439 L440 L443	L260-L291 HydrophobicContact CD1-CB 4.04Å; A287-L291 WeakPolarHBondContact O-CG 3.49Å; A287-L291 PolarHBondContact O-N 3.49Å; L288-L291 PolarHBondContact O-N 2.92Å; L291-V293 PolarHBondContact O-N 3.49Å; L291-E294 WeakPolarHBondContact O-CB 3.22Å; L291-E294 PolarHBondContact O-N 2.71Å; L291-F295 PolarHBondContact O-N 2.67Å; L291-F295 VanDerWaalsContact O-N 3.16Å; L291-L436 HydrophobicContact CD2-CD1 3.47Å; L291-L436 VanDerWaalsContact CD2-CD1 3.47Å; L291-K439 HydrophobicContact CD2-CB 4.31Å; L291-L440 HydrophobicContact CD1-CD2 4Å; L291-L440 HydrophobicContact CD2-CD2 3.83Å; L291-L443 HydrophobicContact CD1-CD1 4.07Å; L291-L443 HydrophobicContact CD1-CD2 4.1Å
292	S	93.5	Very high	90.8	Very high	19 Å²	19	46.1 Å²	46.1	13%	0.133	27%	0.273	C	S	.	.	H	α-helix	trans	-55.9	-34.2	179.4	70.8	0	0	0	0	114.1	G257 L288 K289 G290 E294 F295 A296	G257-S292 WeakPolarHBondContact O-CB 3.41Å; L288-S292 PolarHBondContact O-N 3.18Å; K289-S292 WeakPolarHBondContact O-CB 3.3Å; K289-S292 PolarHBondContact O-N 3.44Å; K289-S292 PolarHBondContact O-OG 3.44Å; G290-S292 PolarHBondContact O-N 2.93Å; S292-E294 VanDerWaalsContact C-N 3.34Å; S292-F295 PolarHBondContact O-N 2.92Å; S292-A296 PolarHBondContact O-N 3.47Å
293	V	92.4	Very high	91.7	Very high	96 Å²	96	45.8 Å²	45.8	58%	0.582	27%	0.265	S	S	*	.	H	α-helix	trans	-67.9	-36.8	178.7	-177.1	0	0	0	0	111.1	G290 L291 A296 L297	G290-V293 PolarHBondContact O-N 3.4Å; L291-V293 PolarHBondContact O-N 3.49Å; V293-A296 PolarHBondContact O-N 2.89Å; V293-L297 PolarHBondContact O-N 3.12Å
294	E	93.6	Very high	92.4	Very high	32 Å²	32	46.1 Å²	46.1	15%	0.15	26%	0.258	C	S	.	.	H	α-helix	trans	-70	-38.7	178.4	-48	-72.2	146.3	0	0	110.8	L291 S292 L297 L298 L436 K439	L291-E294 WeakPolarHBondContact O-CB 3.22Å; L291-E294 PolarHBondContact O-N 2.71Å; S292-E294 VanDerWaalsContact C-N 3.34Å; E294-L297 WeakPolarHBondContact O-CB 3.44Å; E294-L297 PolarHBondContact O-N 3.43Å; E294-L298 WeakPolarHBondContact O-CG 3.34Å; E294-L298 PolarHBondContact O-N 3.18Å; E294-L436 HydrophobicContact CB-CD1 3.63Å; E294-L436 HydrophobicContact CG-CD1 3.68Å; E294-K439 HydrophobicContact CG-CD 4.29Å; E294-K439 IonicContact OE1-NZ 3.53Å; E294-K439 PolarHBondContact OE1-NZ 3.41Å; E294-K439 IonicContact OE2-NZ 2.96Å; E294-K439 PolarHBondContact OE2-NZ 3.17Å
295	F	95.9	Very high	93	Very high	23 Å²	23	44.7 Å²	44.7	10%	0.101	25%	0.25	C	S	.	.	H	α-helix	trans	-67	-34	172.6	-86.5	-90.5	0	0	0	113.1	L253 F256 G257 L260 L291 S292 L297 L298 A299 W433 L436	L253-F295 HydrophobicContact CD2-CD1 3.91Å; L253-F295 HydrophobicContact CD2-CE1 4Å; F256-F295 HydrophobicContact CB-CD1 4.23Å; F256-F295 HydrophobicContact CB-CE1 4.43Å; F256-F295 AromaticContact CD1-CD1 3.62Å; F256-F295 HydrophobicContact CD1-CD1 3.62Å; F256-F295 HydrophobicContact CD1-CD2 4.36Å; F256-F295 AromaticContact CD1-CE1 3.29Å; F256-F295 HydrophobicContact CD1-CE1 3.29Å; F256-F295 HydrophobicContact CD1-CE2 4.09Å; F256-F295 HydrophobicContact CD1-CG 4.15Å; F256-F295 AromaticContact CD1-CZ 3.56Å; F256-F295 HydrophobicContact CD1-CZ 3.56Å; F256-F295 HydrophobicContact CE1-CD1 4.43Å; F256-F295 AromaticContact CE1-CE1 3.74Å; F256-F295 HydrophobicContact CE1-CE1 3.74Å; F256-F295 HydrophobicContact CE1-CE2 4.06Å; F256-F295 AromaticContact CE1-CZ 3.52Å; F256-F295 HydrophobicContact CE1-CZ 3.52Å; F256-F295 HydrophobicContact CG-CD1 4.28Å; F256-F295 HydrophobicContact CG-CE1 4.06Å; G257-F295 VanDerWaalsContact CA-CB 3.49Å; L260-F295 HydrophobicContact CD1-CD2 3.58Å; L260-F295 HydrophobicContact CD1-CE2 3.7Å; L260-F295 HydrophobicContact CD1-CG 4.32Å; L291-F295 PolarHBondContact O-N 2.67Å; L291-F295 VanDerWaalsContact O-N 3.16Å; S292-F295 PolarHBondContact O-N 2.92Å; F295-L297 VanDerWaalsContact C-N 3.33Å; F295-L298 HydrophobicContact CD1-CD1 4.19Å; F295-L298 HydrophobicContact CE1-CD1 4.35Å; F295-L298 HydrophobicContact CG-CD1 4.33Å; F295-L298 PolarHBondContact O-N 3.21Å; F295-A299 WeakPolarHBondContact O-CB 3.17Å; F295-A299 PolarHBondContact O-N 2.78Å; F295-W433 HydrophobicContact CE1-CH2 4.09Å; F295-W433 HydrophobicContact CZ-CH2 4.16Å; F295-W433 HydrophobicContact CZ-CZ3 4.24Å; F295-L436 HydrophobicContact CE2-CD2 4.21Å
296	A	96.5	Very high	93.5	Very high	43 Å²	43	43.5 Å²	43.5	36%	0.355	25%	0.245	S	C	.	.	H	α-helix	trans	-65.7	-34.7	169.9	0	0	0	0	0	112.4	L254 S292 V293 A299 D300	L254-A296 HydrophobicContact CD1-CB 4.25Å; S292-A296 PolarHBondContact O-N 3.47Å; V293-A296 PolarHBondContact O-N 2.89Å; A296-A299 PolarHBondContact O-N 3.47Å; A296-D300 PolarHBondContact O-N 3.33Å
297	L	96.3	Very high	94	Very high	72 Å²	72	42.6 Å²	42.6	38%	0.377	24%	0.239	S	C	.	.	H	α-helix	trans	-71	-40.2	173.6	-177.4	61.1	0	0	0	112.2	V293 E294 F295 A299 D300 K301 V432	V293-L297 PolarHBondContact O-N 3.12Å; E294-L297 WeakPolarHBondContact O-CB 3.44Å; E294-L297 PolarHBondContact O-N 3.43Å; F295-L297 VanDerWaalsContact C-N 3.33Å; L297-A299 VanDerWaalsContact C-N 3.31Å; L297-A299 PolarHBondContact O-N 2.99Å; L297-D300 PolarHBondContact O-N 3.11Å; L297-K301 WeakPolarHBondContact O-CG 3.46Å; L297-K301 PolarHBondContact O-N 3.21Å; L297-V432 HydrophobicContact CB-CG1 4.42Å; L297-V432 HydrophobicContact CD2-CG1 3.99Å; L297-V432 HydrophobicContact CD2-CG2 3.97Å; L297-V432 HydrophobicContact CG-CG1 4.13Å; L297-V432 HydrophobicContact CG-CG2 4.01Å
298	L	97.1	Very high	94.4	Very high	0 Å²	0	45.9 Å²	45.9	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-59.2	-42.7	171.8	-71	165.1	0	0	0	111.2	L253 E294 F295 K301 A302 M429 V432 W433 L436	L253-L298 HydrophobicContact CD1-CB 4.1Å; L253-L298 HydrophobicContact CD2-CB 4.23Å; E294-L298 WeakPolarHBondContact O-CG 3.34Å; E294-L298 PolarHBondContact O-N 3.18Å; F295-L298 HydrophobicContact CD1-CD1 4.19Å; F295-L298 HydrophobicContact CE1-CD1 4.35Å; F295-L298 HydrophobicContact CG-CD1 4.33Å; F295-L298 PolarHBondContact O-N 3.21Å; L298-K301 PolarHBondContact O-N 3.14Å; L298-A302 PolarHBondContact O-N 2.79Å; L298-M429 HydrophobicContact CD2-SD 3.49Å; L298-M429 WeakPolarHBondContact CD2-SD 3.36Å; L298-V432 HydrophobicContact CD2-CB 3.68Å; L298-V432 HydrophobicContact CD2-CG1 3.6Å; L298-V432 HydrophobicContact CG-CB 4.3Å; L298-V432 HydrophobicContact CG-CG1 3.66Å; L298-W433 HydrophobicContact CD1-CD2 4.24Å; L298-W433 HydrophobicContact CD1-CE3 4.06Å; L298-W433 HydrophobicContact CD1-CH2 3.48Å; L298-W433 VanDerWaalsContact CD1-CH2 3.48Å; L298-W433 HydrophobicContact CD1-CZ2 3.67Å; L298-W433 HydrophobicContact CD1-CZ3 3.68Å; L298-W433 HydrophobicContact CD2-CD2 3.92Å; L298-W433 HydrophobicContact CD2-CG 4.22Å; L298-W433 HydrophobicContact CD2-CZ2 3.94Å; L298-W433 HydrophobicContact CG-CZ2 4.4Å; L298-L436 HydrophobicContact CD1-CD2 4.43Å
299	A	98	Very high	94.7	Very high	6 Å²	6	44.8 Å²	44.8	5%	0.05	24%	0.244	C	C	.	.	H	α-helix	trans	-62.1	-46.8	175	0	0	0	0	0	112.7	A250 L253 L254 F295 A296 L297 K301 A302 A303	A250-A299 VanDerWaalsContact CB-O 3.29Å; A250-A299 WeakPolarHBondContact CB-O 3.36Å; A250-A299 VanDerWaalsContact O-CB 3.22Å; A250-A299 WeakPolarHBondContact O-CB 3.43Å; L253-A299 HydrophobicContact CB-CB 4.01Å; L254-A299 HydrophobicContact CB-CB 3.77Å; F295-A299 WeakPolarHBondContact O-CB 3.17Å; F295-A299 PolarHBondContact O-N 2.78Å; A296-A299 PolarHBondContact O-N 3.47Å; L297-A299 VanDerWaalsContact C-N 3.31Å; L297-A299 PolarHBondContact O-N 2.99Å; A299-K301 VanDerWaalsContact C-N 3.27Å; A299-K301 PolarHBondContact O-N 3.44Å; A299-A302 PolarHBondContact O-N 3.1Å; A299-A303 WeakPolarHBondContact O-CB 3.21Å; A299-A303 PolarHBondContact O-N 3.23Å
300	D	97.6	Very high	95	Very high	69 Å²	69	42.6 Å²	42.6	37%	0.369	24%	0.235	S	C	.	.	H	α-helix	trans	-55.4	-42.2	174.3	175.1	59.9	0	0	0	111.7	A296 L297 A303 Q304	A296-D300 PolarHBondContact O-N 3.33Å; L297-D300 PolarHBondContact O-N 3.11Å; D300-A303 PolarHBondContact O-N 3.2Å; D300-Q304 WeakPolarHBondContact O-CB 3.45Å; D300-Q304 VanDerWaalsContact O-CG 3.23Å; D300-Q304 WeakPolarHBondContact O-CG 3.41Å; D300-Q304 PolarHBondContact O-N 3.47Å; D300-Q304 PolarHBondContact OD1-NE2 3.23Å; D300-Q304 PolarHBondContact OD2-NE2 3.05Å
301	K	96.8	Very high	95.3	Very high	45 Å²	45	43.5 Å²	43.5	20%	0.196	23%	0.23	C	C	.	.	H	α-helix	trans	-70.2	-37.5	177.6	-65.1	-45.6	-173.6	170.5	0	114.3	L297 L298 A299 Q305 E428 M429 V432	L297-K301 WeakPolarHBondContact O-CG 3.46Å; L297-K301 PolarHBondContact O-N 3.21Å; L298-K301 PolarHBondContact O-N 3.14Å; A299-K301 VanDerWaalsContact C-N 3.27Å; A299-K301 PolarHBondContact O-N 3.44Å; K301-Q305 PolarHBondContact O-N 2.82Å; K301-E428 HydrophobicContact CD-CB 4.48Å; K301-E428 WeakPolarHBondContact CD-OE2 3.47Å; K301-E428 WeakPolarHBondContact CE-OE2 3.29Å; K301-E428 IonicContact NZ-OE2 2.67Å; K301-E428 PolarHBondContact NZ-OE2 3.03Å; K301-M429 HydrophobicContact CB-CE 4.16Å; K301-V432 HydrophobicContact CG-CG2 4.42Å
302	A	96.9	Very high	95.5	Very high	1 Å²	1	45.4 Å²	45.4	1%	0.008	24%	0.24	C	C	.	.	H	α-helix	trans	-64	-43	171.6	0	0	0	0	0	111.9	A246 N249 A250 L253 L298 A299 Q305 G306 M429	A246-A302 CarbonylContact O-C 3.55Å; N249-A302 WeakPolarHBondContact ND2-CB 3.38Å; A250-A302 HydrophobicContact CB-CB 3.7Å; L253-A302 HydrophobicContact CD1-CB 4.11Å; L298-A302 PolarHBondContact O-N 2.79Å; A299-A302 PolarHBondContact O-N 3.1Å; A302-Q305 PolarHBondContact O-N 2.96Å; A302-G306 PolarHBondContact O-N 2.94Å; A302-M429 HydrophobicContact CB-CE 3.97Å
303	A	97.3	Very high	95.7	Very high	38 Å²	38	44.7 Å²	44.7	31%	0.314	24%	0.235	S	C	.	.	H	α-helix	trans	-66.5	-40.6	177.8	0	0	0	0	0	112.4	A250 A299 D300 G306 K307	A250-A303 HydrophobicContact CB-CB 3.81Å; A299-A303 WeakPolarHBondContact O-CB 3.21Å; A299-A303 PolarHBondContact O-N 3.23Å; D300-A303 PolarHBondContact O-N 3.2Å; A303-G306 PolarHBondContact O-N 3.39Å; A303-K307 WeakPolarHBondContact O-CB 3.41Å; A303-K307 PolarHBondContact O-N 3.46Å
304	Q	95.8	Very high	95.9	Very high	82 Å²	82	40.4 Å²	40.4	38%	0.383	21%	0.209	S	C	.	.	H	α-helix	trans	-62.9	-42	174	-75.1	171.1	17.7	0	0	111.6	D300 K307 Q308	D300-Q304 WeakPolarHBondContact O-CB 3.45Å; D300-Q304 VanDerWaalsContact O-CG 3.23Å; D300-Q304 WeakPolarHBondContact O-CG 3.41Å; D300-Q304 PolarHBondContact O-N 3.47Å; D300-Q304 PolarHBondContact OD1-NE2 3.23Å; D300-Q304 PolarHBondContact OD2-NE2 3.05Å; Q304-K307 PolarHBondContact O-N 3.21Å; Q304-Q308 WeakPolarHBondContact O-CB 3.48Å; Q304-Q308 PolarHBondContact O-N 2.82Å
305	Q	94.8	Very high	96.1	Very high	26 Å²	26	40.2 Å²	40.2	12%	0.121	21%	0.208	C	C	.	.	H	α-helix	trans	-60.3	-51.2	174	177.7	175.7	-19.1	0	0	111.7	K301 A302 K307 Q308 E309	K301-Q305 PolarHBondContact O-N 2.82Å; A302-Q305 PolarHBondContact O-N 2.96Å; Q305-K307 VanDerWaalsContact C-N 3.3Å; Q305-K307 PolarHBondContact O-N 2.84Å; Q305-Q308 PolarHBondContact O-N 3.36Å; Q305-E309 HydrophobicContact CG-CG 4.46Å; Q305-E309 WeakPolarHBondContact CG-OE1 3.46Å; Q305-E309 PolarHBondContact NE2-OE1 3.48Å; Q305-E309 WeakPolarHBondContact O-CG 3.41Å; Q305-E309 PolarHBondContact O-N 3.4Å
306	G	95.9	Very high	96.1	Very high	0 Å²	0	41.9 Å²	41.9	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-59.7	-40.8	-179.9	0	0	0	0	0	112.8	A302 A303 E309 E310	A302-G306 PolarHBondContact O-N 2.94Å; A303-G306 PolarHBondContact O-N 3.39Å; G306-E309 PolarHBondContact O-N 3.28Å; G306-E310 PolarHBondContact O-N 3.27Å
307	K	94.8	Very high	96.2	Very high	137 Å²	137	39.9 Å²	39.9	60%	0.596	20%	0.199	S	C	*	.	H	α-helix	trans	-65.7	-37.4	173.8	-172.1	177.8	179.6	-175.9	0	112.5	A303 Q304 Q305 N311	A303-K307 WeakPolarHBondContact O-CB 3.41Å; A303-K307 PolarHBondContact O-N 3.46Å; Q304-K307 PolarHBondContact O-N 3.21Å; Q305-K307 VanDerWaalsContact C-N 3.3Å; Q305-K307 PolarHBondContact O-N 2.84Å; K307-N311 PolarHBondContact O-N 2.9Å; K307-N311 VanDerWaalsContact O-N 3.12Å; K307-N311 PolarHBondContact O-ND2 2.92Å
308	Q	93.6	Very high	96.3	Very high	94 Å²	94	37.4 Å²	37.4	44%	0.439	19%	0.186	S	C	.	.	H	α-helix	trans	-66.4	-45.4	175.9	-164.1	67.3	22.7	0	0	110.8	Q304 Q305 E310 N311 D312	Q304-Q308 WeakPolarHBondContact O-CB 3.48Å; Q304-Q308 PolarHBondContact O-N 2.82Å; Q305-Q308 PolarHBondContact O-N 3.36Å; Q308-E310 VanDerWaalsContact C-N 3.31Å; Q308-E310 PolarHBondContact O-N 3.26Å; Q308-N311 PolarHBondContact O-N 3.48Å; Q308-D312 PolarHBondContact NE2-OD2 3.13Å; Q308-D312 WeakPolarHBondContact O-CB 3.33Å; Q308-D312 PolarHBondContact O-N 3.45Å
309	E	95.8	Very high	96.4	Very high	3 Å²	3	38.7 Å²	38.7	1%	0.014	19%	0.193	C	C	.	.	H	α-helix	trans	-59.2	-41	177.2	-69.8	178.1	-161	0	0	112.4	I242 A243 Q305 G306 V313 V314 S421 Q422	I242-E309 WeakPolarHBondContact CG2-OE2 3.25Å; A243-E309 HydrophobicContact CB-CB 3.91Å; A243-E309 PolarHBondContact N-OE2 2.93Å; Q305-E309 HydrophobicContact CG-CG 4.46Å; Q305-E309 WeakPolarHBondContact CG-OE1 3.46Å; Q305-E309 PolarHBondContact NE2-OE1 3.48Å; Q305-E309 WeakPolarHBondContact O-CG 3.41Å; Q305-E309 PolarHBondContact O-N 3.4Å; G306-E309 PolarHBondContact O-N 3.28Å; E309-V313 WeakPolarHBondContact O-CA 3.39Å; E309-V313 WeakPolarHBondContact O-CB 3.21Å; E309-V313 PolarHBondContact O-N 3.47Å; E309-V314 PolarHBondContact O-N 3.45Å; E309-S421 WeakPolarHBondContact CG-OG 3.33Å; E309-Q422 VanDerWaalsContact CD-NE2 3.34Å; E309-Q422 PolarHBondContact OE1-NE2 3.3Å
310	E	96	Very high	96.4	Very high	55 Å²	55	38.5 Å²	38.5	26%	0.257	19%	0.191	S	C	.	.	I	π-helix	trans	-58.2	-54.6	173.1	-173.7	-166	-139.3	0	0	111.8	R150 G306 Q308 V314 E315	R150-E310 IonicContact CZ-OE1 3.97Å; R150-E310 IonicContact CZ-OE2 3.14Å; R150-E310 IonicContact NH1-OE1 2.69Å; R150-E310 PolarHBondContact NH1-OE1 3.4Å; R150-E310 IonicContact NH1-OE2 3.19Å; R150-E310 IonicContact NH2-OE1 3.63Å; R150-E310 PolarHBondContact NH2-OE1 3.11Å; R150-E310 IonicContact NH2-OE2 3.86Å; R150-E310 PolarHBondContact NH2-OE2 3.4Å; G306-E310 PolarHBondContact O-N 3.27Å; Q308-E310 VanDerWaalsContact C-N 3.31Å; Q308-E310 PolarHBondContact O-N 3.26Å; E310-V314 WeakPolarHBondContact O-CB 3.48Å; E310-V314 PolarHBondContact O-N 3.32Å; E310-E315 PolarHBondContact O-N 2.77Å
311	N	93.5	Very high	96.5	Very high	60 Å²	60	35.6 Å²	35.6	32%	0.321	18%	0.175	S	C	.	.	I	π-helix	trans	-77.8	-28.6	-171.3	-71.6	-85.5	0	0	0	113.5	K307 Q308	K307-N311 PolarHBondContact O-N 2.9Å; K307-N311 VanDerWaalsContact O-N 3.12Å; K307-N311 PolarHBondContact O-ND2 2.92Å; Q308-N311 PolarHBondContact O-N 3.48Å
312	D	92.9	Very high	96.6	Very high	52 Å²	52	35.5 Å²	35.5	28%	0.278	18%	0.177	S	C	.	.	I	π-helix	trans	-101.9	-27	-178.1	-103.5	-21.2	0	0	0	114.7	Q308 K316 A417	Q308-D312 PolarHBondContact NE2-OD2 3.13Å; Q308-D312 WeakPolarHBondContact O-CB 3.33Å; Q308-D312 PolarHBondContact O-N 3.45Å; D312-K316 WeakPolarHBondContact O-CD 3.33Å; D312-K316 WeakPolarHBondContact O-CE 3.45Å; D312-K316 WeakPolarHBondContact O-CG 3.08Å; D312-K316 PolarHBondContact O-NZ 2.82Å; D312-K316 IonicContact OD1-NZ 3.34Å; D312-K316 PolarHBondContact OD1-NZ 3.21Å; D312-A417 HydrophobicContact CB-CB 4.42Å
313	V	97.4	Very high	96.6	Very high	4 Å²	4	35.9 Å²	35.9	2%	0.024	18%	0.179	C	C	.	.	I	π-helix	trans	-109.2	-55.4	-176.8	-167.9	0	0	0	0	110.7	A239 E309 K316 L317 I414 A417 F418	A239-V313 HydrophobicContact CB-CG1 4.13Å; E309-V313 WeakPolarHBondContact O-CA 3.39Å; E309-V313 WeakPolarHBondContact O-CB 3.21Å; E309-V313 PolarHBondContact O-N 3.47Å; V313-K316 PolarHBondContact O-N 2.79Å; V313-L317 HydrophobicContact CG1-CD1 4.01Å; V313-L317 WeakPolarHBondContact O-CG 3.41Å; V313-L317 PolarHBondContact O-N 2.71Å; V313-I414 HydrophobicContact CG1-CG2 4.37Å; V313-A417 HydrophobicContact CG2-CB 4.42Å; V313-F418 HydrophobicContact CG1-CB 3.96Å; V313-F418 HydrophobicContact CG1-CD2 4.24Å; V313-F418 HydrophobicContact CG2-CB 4Å; V313-F418 HydrophobicContact CG2-CD2 4.32Å
314	V	98.1	Very high	96.7	Very high	6 Å²	6	34.1 Å²	34.1	4%	0.036	16%	0.164	C	C	.	.	I	π-helix	trans	-65.7	-43.1	-176.2	-175.2	0	0	0	0	110.8	R236 A239 E240 E309 E310 K316 L317 N318	R236-V314 HydrophobicContact CG-CG1 4.29Å; A239-V314 HydrophobicContact CB-CG2 4.02Å; E240-V314 HydrophobicContact CB-CG1 4.22Å; E240-V314 HydrophobicContact CB-CG2 4.26Å; E309-V314 PolarHBondContact O-N 3.45Å; E310-V314 WeakPolarHBondContact O-CB 3.48Å; E310-V314 PolarHBondContact O-N 3.32Å; V314-K316 PolarHBondContact O-N 2.88Å; V314-L317 WeakPolarHBondContact O-CB 3.25Å; V314-L317 PolarHBondContact O-N 3.44Å; V314-N318 WeakPolarHBondContact O-CB 3.49Å; V314-N318 VanDerWaalsContact O-CG 3.29Å; V314-N318 PolarHBondContact O-N 2.82Å; V314-N318 PolarHBondContact O-ND2 2.98Å
315	E	96.9	Very high	96.8	Very high	29 Å²	29	32.5 Å²	32.5	14%	0.136	16%	0.157	C	C	.	.	H	α-helix	trans	-68.5	-30.1	177.3	-79	-61	101.5	0	0	114.3	R150 R154 E310 N318 L319	R150-E315 WeakPolarHBondContact CB-OE2 3.49Å; R154-E315 WeakPolarHBondContact CD-OE2 3.44Å; R154-E315 IonicContact CZ-OE1 3.08Å; R154-E315 IonicContact CZ-OE2 3.95Å; R154-E315 IonicContact NE-OE2 2.66Å; R154-E315 IonicContact NH1-OE1 3.73Å; R154-E315 PolarHBondContact NH1-OE1 2.99Å; R154-E315 IonicContact NH1-OE2 3.53Å; R154-E315 PolarHBondContact NH1-OE2 2.73Å; E310-E315 PolarHBondContact O-N 2.77Å; E315-N318 PolarHBondContact OE1-ND2 3.48Å; E315-L319 WeakPolarHBondContact O-CB 3.47Å; E315-L319 PolarHBondContact O-N 2.84Å
316	K	96.9	Very high	97	Very high	57 Å²	57	31.3 Å²	31.3	25%	0.248	15%	0.151	C	C	.	.	H	α-helix	trans	-73.7	-34.2	173	-61.1	-167.4	-145.2	-31.3	0	111.7	D312 V313 V314 F320 I414	D312-K316 WeakPolarHBondContact O-CD 3.33Å; D312-K316 WeakPolarHBondContact O-CE 3.45Å; D312-K316 WeakPolarHBondContact O-CG 3.08Å; D312-K316 PolarHBondContact O-NZ 2.82Å; D312-K316 IonicContact OD1-NZ 3.34Å; D312-K316 PolarHBondContact OD1-NZ 3.21Å; V313-K316 PolarHBondContact O-N 2.79Å; V314-K316 PolarHBondContact O-N 2.88Å; K316-F320 PolarHBondContact O-N 3.4Å; K316-I414 HydrophobicContact CB-CD1 4.49Å; K316-I414 HydrophobicContact CB-CG1 3.7Å
317	L	98.5	Very high	97.2	Very high	1 Å²	1	31.3 Å²	31.3	1%	0.005	15%	0.151	C	C	.	.	H	α-helix	trans	-65.6	-46.4	170.3	-76.5	162.7	0	0	0	111.5	F232 L235 R236 A239 V313 V314 L319 F320 L321 I414	F232-L317 HydrophobicContact CD1-CD2 3.78Å; F232-L317 HydrophobicContact CE1-CD2 4.33Å; L235-L317 HydrophobicContact CB-CD2 4.45Å; L235-L317 HydrophobicContact CD2-CD2 3.88Å; L235-L317 HydrophobicContact CG-CD1 4.34Å; L235-L317 HydrophobicContact CG-CD2 4Å; R236-L317 HydrophobicContact CB-CB 4.12Å; R236-L317 HydrophobicContact CB-CD1 4.46Å; R236-L317 HydrophobicContact CG-CB 4.11Å; A239-L317 HydrophobicContact CB-CD1 3.65Å; V313-L317 HydrophobicContact CG1-CD1 4.01Å; V313-L317 WeakPolarHBondContact O-CG 3.41Å; V313-L317 PolarHBondContact O-N 2.71Å; V314-L317 WeakPolarHBondContact O-CB 3.25Å; V314-L317 PolarHBondContact O-N 3.44Å; L317-L319 VanDerWaalsContact C-N 3.35Å; L317-L319 PolarHBondContact O-N 3.38Å; L317-F320 PolarHBondContact O-N 2.96Å; L317-L321 WeakPolarHBondContact O-CB 3.46Å; L317-L321 WeakPolarHBondContact O-CG 3.41Å; L317-L321 PolarHBondContact O-N 2.94Å; L317-I414 HydrophobicContact CD1-CG2 4.24Å; L317-I414 HydrophobicContact CD2-CD1 4.14Å; L317-I414 HydrophobicContact CD2-CG2 3.83Å; L317-I414 HydrophobicContact CG-CD1 4.41Å; L317-I414 HydrophobicContact CG-CG2 3.77Å
318	N	98.4	Very high	97.3	Very high	21 Å²	21	27.3 Å²	27.3	11%	0.112	13%	0.133	C	C	.	.	H	α-helix	trans	-60.1	-42.4	175.5	-72.1	-26.1	0	0	0	111.3	R236 V314 E315 F320 L321 D322	R236-N318 WeakPolarHBondContact CG-OD1 3.4Å; R236-N318 PolarHBondContact NH1-OD1 2.66Å; V314-N318 WeakPolarHBondContact O-CB 3.49Å; V314-N318 VanDerWaalsContact O-CG 3.29Å; V314-N318 PolarHBondContact O-N 2.82Å; V314-N318 PolarHBondContact O-ND2 2.98Å; E315-N318 PolarHBondContact OE1-ND2 3.48Å; N318-F320 VanDerWaalsContact C-N 3.32Å; N318-F320 PolarHBondContact O-N 3.01Å; N318-L321 PolarHBondContact O-N 3.23Å; N318-D322 WeakPolarHBondContact O-CB 3.45Å; N318-D322 PolarHBondContact O-N 2.69Å
319	L	98.3	Very high	97.6	Very high	27 Å²	27	24.8 Å²	24.8	14%	0.141	12%	0.123	C	C	.	.	H	α-helix	trans	-58.3	-42.4	176.8	-177.7	68.8	0	0	0	112.4	R154 L158 E315 L317 L323	R154-L319 HydrophobicContact CB-CD1 3.82Å; R154-L319 HydrophobicContact CG-CB 4.47Å; R154-L319 HydrophobicContact CG-CD1 4.08Å; L158-L319 HydrophobicContact CD1-CD1 4.25Å; L158-L319 HydrophobicContact CD2-CD1 3.81Å; L158-L319 HydrophobicContact CD2-CG 4.31Å; L158-L319 HydrophobicContact CG-CD1 3.73Å; E315-L319 WeakPolarHBondContact O-CB 3.47Å; E315-L319 PolarHBondContact O-N 2.84Å; L317-L319 VanDerWaalsContact C-N 3.35Å; L317-L319 PolarHBondContact O-N 3.38Å; L319-L323 PolarHBondContact O-N 3.42Å
320	F	98.4	Very high	97.7	Very high	1 Å²	1	24.7 Å²	24.7	0%	0.004	12%	0.122	C	C	.	.	H	α-helix	trans	-73	-36.3	178.3	-168.6	-133.4	0	0	0	112	I228 F232 K316 L317 N318 L323 L324 L408 L410	I228-F320 HydrophobicContact CG2-CE1 4.16Å; I228-F320 HydrophobicContact CG2-CZ 4.36Å; F232-F320 AromaticContact CD1-CD1 3.6Å; F232-F320 HydrophobicContact CD1-CD1 3.6Å; F232-F320 AromaticContact CD1-CE1 3.98Å; F232-F320 HydrophobicContact CD1-CE1 3.98Å; F232-F320 HydrophobicContact CD2-CD1 4.32Å; F232-F320 AromaticContact CD2-CE1 3.95Å; F232-F320 HydrophobicContact CD2-CE1 3.95Å; F232-F320 AromaticContact CE1-CD1 3.75Å; F232-F320 HydrophobicContact CE1-CD1 3.75Å; F232-F320 AromaticContact CE1-CE1 3.88Å; F232-F320 HydrophobicContact CE1-CE1 3.88Å; F232-F320 HydrophobicContact CE2-CD1 4.46Å; F232-F320 AromaticContact CE2-CE1 3.86Å; F232-F320 HydrophobicContact CE2-CE1 3.86Å; F232-F320 AromaticContact CG-CD1 3.9Å; F232-F320 HydrophobicContact CG-CD1 3.9Å; F232-F320 HydrophobicContact CG-CE1 4.01Å; F232-F320 HydrophobicContact CZ-CD1 4.19Å; F232-F320 AromaticContact CZ-CE1 3.82Å; F232-F320 HydrophobicContact CZ-CE1 3.82Å; K316-F320 PolarHBondContact O-N 3.4Å; L317-F320 PolarHBondContact O-N 2.96Å; N318-F320 VanDerWaalsContact C-N 3.32Å; N318-F320 PolarHBondContact O-N 3.01Å; F320-L323 HydrophobicContact CD2-CD2 4.32Å; F320-L323 PolarHBondContact O-N 3.06Å; F320-L324 HydrophobicContact CD1-CD1 3.76Å; F320-L324 HydrophobicContact CD2-CD1 4.44Å; F320-L324 HydrophobicContact CD2-CG 4.43Å; F320-L324 HydrophobicContact CE1-CD1 3.64Å; F320-L324 HydrophobicContact CE1-CG 4.39Å; F320-L324 HydrophobicContact CE2-CD1 4.32Å; F320-L324 HydrophobicContact CE2-CD2 4.34Å; F320-L324 HydrophobicContact CE2-CG 4.22Å; F320-L324 HydrophobicContact CG-CD1 4.16Å; F320-L324 HydrophobicContact CZ-CD1 3.91Å; F320-L324 HydrophobicContact CZ-CD2 4.13Å; F320-L324 HydrophobicContact CZ-CG 4.18Å; F320-L324 WeakPolarHBondContact O-CB 3.33Å; F320-L324 WeakPolarHBondContact O-CG 3.45Å; F320-L324 PolarHBondContact O-N 3.31Å; F320-L408 HydrophobicContact CZ-CD2 4.03Å; F320-L410 HydrophobicContact CB-CD2 3.99Å; F320-L410 HydrophobicContact CD2-CD2 4.29Å; F320-L410 HydrophobicContact CG-CD2 4.37Å
321	L	98.7	Very high	97.8	Very high	8 Å²	8	22.2 Å²	22.2	4%	0.042	11%	0.111	C	C	.	.	H	α-helix	trans	-66	-40.1	174.5	-76.2	171.8	0	0	0	113.1	Y229 F232 H233 R236 L317 N318 L323 L324 Q325	Y229-L321 HydrophobicContact CD2-CD2 3.84Å; Y229-L321 HydrophobicContact CE2-CD2 3.89Å; Y229-L321 HydrophobicContact CG-CD2 4.39Å; F232-L321 HydrophobicContact CB-CD2 3.87Å; F232-L321 HydrophobicContact CB-CG 4.39Å; H233-L321 HydrophobicContact CB-CD2 4.2Å; R236-L321 HydrophobicContact CB-CD1 3.76Å; R236-L321 HydrophobicContact CG-CD1 4.03Å; L317-L321 WeakPolarHBondContact O-CB 3.46Å; L317-L321 WeakPolarHBondContact O-CG 3.41Å; L317-L321 PolarHBondContact O-N 2.94Å; N318-L321 PolarHBondContact O-N 3.23Å; L321-L323 VanDerWaalsContact C-N 3.32Å; L321-L323 PolarHBondContact O-N 3.16Å; L321-L324 PolarHBondContact O-N 2.88Å; L321-Q325 WeakPolarHBondContact O-CB 3.22Å; L321-Q325 PolarHBondContact O-N 2.71Å
322	D	98.7	Very high	98	Very high	43 Å²	43	24 Å²	24	23%	0.23	12%	0.118	C	C	.	.	H	α-helix	trans	-61.6	-41.9	175.1	-68.2	-24.7	0	0	0	110.5	R154 L158 N318 Q325 S326	R154-D322 IonicContact CZ-OD2 2.71Å; R154-D322 IonicContact NE-OD2 3.49Å; R154-D322 PolarHBondContact NE-OD2 2.76Å; R154-D322 IonicContact NH2-OD1 3.49Å; R154-D322 IonicContact NH2-OD2 2.68Å; R154-D322 PolarHBondContact NH2-OD2 3.5Å; L158-D322 HydrophobicContact CD1-CB 3.84Å; N318-D322 WeakPolarHBondContact O-CB 3.45Å; N318-D322 PolarHBondContact O-N 2.69Å; D322-Q325 PolarHBondContact O-N 3.38Å; D322-S326 PolarHBondContact O-N 2.72Å; D322-S326 PolarHBondContact O-OG 2.68Å
323	L	98.6	Very high	98.3	Very high	10 Å²	10	24.5 Å²	24.5	5%	0.052	12%	0.116	C	C	.	.	H	α-helix	trans	-63.8	-47.4	173.6	175.9	64.5	0	0	0	112.4	M128 L158 L319 F320 L321 Q325 S326 Y327 I404 Y407	M128-L323 HydrophobicContact CE-CD1 3.98Å; M128-L323 HydrophobicContact SD-CD1 4.28Å; L158-L323 HydrophobicContact CD1-CB 4.21Å; L158-L323 HydrophobicContact CD2-CB 4.01Å; L158-L323 HydrophobicContact CD2-CD1 4.43Å; L319-L323 PolarHBondContact O-N 3.42Å; F320-L323 HydrophobicContact CD2-CD2 4.32Å; F320-L323 PolarHBondContact O-N 3.06Å; L321-L323 VanDerWaalsContact C-N 3.32Å; L321-L323 PolarHBondContact O-N 3.16Å; L323-Q325 VanDerWaalsContact C-N 3.29Å; L323-Q325 PolarHBondContact O-N 3.01Å; L323-S326 VanDerWaalsContact O-CB 3.22Å; L323-S326 WeakPolarHBondContact O-CB 3.27Å; L323-S326 PolarHBondContact O-N 3.35Å; L323-S326 VanDerWaalsContact O-N 3.11Å; L323-Y327 PolarHBondContact O-N 3.28Å; L323-Y327 VanDerWaalsContact O-N 3.13Å; L323-I404 HydrophobicContact CD1-CD1 3.94Å; L323-I404 HydrophobicContact CD2-CD1 4.01Å; L323-I404 HydrophobicContact CG-CD1 3.58Å; L323-Y407 HydrophobicContact CD2-CD1 3.92Å; L323-Y407 HydrophobicContact CD2-CD2 3.45Å; L323-Y407 VanDerWaalsContact CD2-CD2 3.45Å; L323-Y407 HydrophobicContact CD2-CE1 4.49Å; L323-Y407 HydrophobicContact CD2-CE2 4.08Å; L323-Y407 HydrophobicContact CD2-CG 3.36Å
324	L	98.7	Very high	98.3	Very high	0 Å²	0	24.4 Å²	24.4	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-65.5	-31.2	178	-68.8	165.9	0	0	0	112.3	I225 I228 Y229 F320 L321 K328 I404	I225-L324 HydrophobicContact CG2-CD2 3.82Å; I228-L324 HydrophobicContact CG2-CD1 3.93Å; I228-L324 HydrophobicContact CG2-CD2 4.07Å; Y229-L324 HydrophobicContact CD2-CB 3.84Å; F320-L324 HydrophobicContact CD1-CD1 3.76Å; F320-L324 HydrophobicContact CD2-CD1 4.44Å; F320-L324 HydrophobicContact CD2-CG 4.43Å; F320-L324 HydrophobicContact CE1-CD1 3.64Å; F320-L324 HydrophobicContact CE1-CG 4.39Å; F320-L324 HydrophobicContact CE2-CD1 4.32Å; F320-L324 HydrophobicContact CE2-CD2 4.34Å; F320-L324 HydrophobicContact CE2-CG 4.22Å; F320-L324 HydrophobicContact CG-CD1 4.16Å; F320-L324 HydrophobicContact CZ-CD1 3.91Å; F320-L324 HydrophobicContact CZ-CD2 4.13Å; F320-L324 HydrophobicContact CZ-CG 4.18Å; F320-L324 WeakPolarHBondContact O-CB 3.33Å; F320-L324 WeakPolarHBondContact O-CG 3.45Å; F320-L324 PolarHBondContact O-N 3.31Å; L321-L324 PolarHBondContact O-N 2.88Å; L324-K328 WeakPolarHBondContact O-CG 3.47Å; L324-K328 PolarHBondContact O-N 3.08Å; L324-I404 HydrophobicContact CD2-CD1 4.4Å; L324-I404 HydrophobicContact CD2-CG2 3.91Å
325	Q	98.6	Very high	98.3	Very high	49 Å²	49	27 Å²	27	23%	0.229	13%	0.127	C	C	.	.	H	α-helix	trans	-68.8	-41.2	170.4	-174	60.2	43.7	0	0	111.1	Y229 L321 D322 L323 Y327 K328 D329	Y229-Q325 HydrophobicContact CE2-CB 4.13Å; L321-Q325 WeakPolarHBondContact O-CB 3.22Å; L321-Q325 PolarHBondContact O-N 2.71Å; D322-Q325 PolarHBondContact O-N 3.38Å; L323-Q325 VanDerWaalsContact C-N 3.29Å; L323-Q325 PolarHBondContact O-N 3.01Å; Q325-Y327 PolarHBondContact O-N 2.84Å; Q325-K328 WeakPolarHBondContact O-CB 3.27Å; Q325-K328 PolarHBondContact O-N 2.97Å; Q325-D329 PolarHBondContact NE2-OD1 3.44Å; Q325-D329 VanDerWaalsContact O-CG 3.25Å; Q325-D329 PolarHBondContact O-N 3.39Å
326	S	98.7	Very high	98.2	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-55.5	-37.7	175	-48.7	0	0	0	0	112.2	P130 D322 L323 L330	P130-S326 WeakPolarHBondContact CA-OG 3.33Å; P130-S326 WeakPolarHBondContact CB-OG 3.49Å; D322-S326 PolarHBondContact O-N 2.72Å; D322-S326 PolarHBondContact O-OG 2.68Å; L323-S326 VanDerWaalsContact O-CB 3.22Å; L323-S326 WeakPolarHBondContact O-CB 3.27Å; L323-S326 PolarHBondContact O-N 3.35Å; L323-S326 VanDerWaalsContact O-N 3.11Å; S326-L330 WeakPolarHBondContact O-CB 3.34Å; S326-L330 PolarHBondContact O-N 2.78Å; S326-L330 VanDerWaalsContact O-N 3.11Å
327	Y	98.8	Very high	98.2	Very high	1 Å²	1	30.1 Å²	30.1	0%	0.004	15%	0.146	C	C	.	.	H	α-helix	trans	-67.3	-45.5	172.7	-175.5	-89.2	0	0	0	112.6	M128 I225 L323 Q325 D329 L330 C331 L397 T401 I404	M128-Y327 HydrophobicContact SD-CD2 3.81Å; M128-Y327 HydrophobicContact SD-CG 4.22Å; I225-Y327 HydrophobicContact CB-CD1 3.99Å; I225-Y327 HydrophobicContact CB-CE1 4.04Å; I225-Y327 HydrophobicContact CD1-CD1 3.84Å; I225-Y327 HydrophobicContact CD1-CD2 4.06Å; I225-Y327 HydrophobicContact CD1-CE1 3.57Å; I225-Y327 HydrophobicContact CD1-CE2 3.82Å; I225-Y327 HydrophobicContact CD1-CG 4.09Å; I225-Y327 HydrophobicContact CG1-CE1 4.39Å; I225-Y327 HydrophobicContact CG2-CD1 3.46Å; I225-Y327 VanDerWaalsContact CG2-CD1 3.46Å; I225-Y327 HydrophobicContact CG2-CE1 4.05Å; I225-Y327 HydrophobicContact CG2-CG 4Å; L323-Y327 PolarHBondContact O-N 3.28Å; L323-Y327 VanDerWaalsContact O-N 3.13Å; Q325-Y327 PolarHBondContact O-N 2.84Å; Y327-D329 VanDerWaalsContact C-N 3.33Å; Y327-D329 PolarHBondContact O-N 2.81Å; Y327-L330 WeakPolarHBondContact O-CB 3.45Å; Y327-L330 PolarHBondContact O-N 3.31Å; Y327-L330 VanDerWaalsContact O-N 3.16Å; Y327-C331 WeakPolarHBondContact CE1-SG 3.24Å; Y327-C331 PolarHBondContact O-N 2.76Å; Y327-C331 PolarHBondContact O-SG 3.23Å; Y327-L397 HydrophobicContact CE2-CD2 4.24Å; Y327-T401 WeakPolarHBondContact CE2-OG1 3.46Å; Y327-T401 PolarHBondContact OH-OG1 2.94Å; Y327-I404 HydrophobicContact CD2-CG1 3.94Å; Y327-I404 HydrophobicContact CG-CG1 4.21Å
328	K	98.6	Very high	98.1	Very high	52 Å²	52	31 Å²	31	23%	0.226	15%	0.151	C	C	.	.	H	α-helix	trans	-60	-43.8	176.7	-70.6	160.5	58.7	-164.9	0	111.5	Y229 L324 Q325 L330 C331 E332	Y229-K328 HydrophobicContact CD1-CD 4.27Å; Y229-K328 VanDerWaalsContact CD1-NZ 3.29Å; Y229-K328 HydrophobicContact CD2-CD 3.92Å; Y229-K328 HydrophobicContact CE2-CD 4.45Å; Y229-K328 HydrophobicContact CG-CD 3.84Å; Y229-K328 VanDerWaalsContact CZ-NZ 3.31Å; L324-K328 WeakPolarHBondContact O-CG 3.47Å; L324-K328 PolarHBondContact O-N 3.08Å; Q325-K328 WeakPolarHBondContact O-CB 3.27Å; Q325-K328 PolarHBondContact O-N 2.97Å; K328-L330 VanDerWaalsContact C-N 3.27Å; K328-L330 PolarHBondContact O-N 3.44Å; K328-C331 WeakPolarHBondContact O-CB 3.34Å; K328-C331 PolarHBondContact O-N 3.12Å; K328-E332 WeakPolarHBondContact O-CG 3.49Å; K328-E332 PolarHBondContact O-N 3.03Å
329	D	98.5	Very high	97.9	Very high	41 Å²	41	31.5 Å²	31.5	22%	0.219	15%	0.154	C	C	.	.	H	α-helix	trans	-64	-34.2	177	-61.1	-19.7	0	0	0	111.5	Q325 Y327 E332 R333	Q325-D329 PolarHBondContact NE2-OD1 3.44Å; Q325-D329 VanDerWaalsContact O-CG 3.25Å; Q325-D329 PolarHBondContact O-N 3.39Å; Y327-D329 VanDerWaalsContact C-N 3.33Å; Y327-D329 PolarHBondContact O-N 2.81Å; D329-E332 PolarHBondContact O-N 3.26Å; D329-R333 WeakPolarHBondContact O-CG 3.35Å; D329-R333 PolarHBondContact O-N 2.98Å; D329-R333 PolarHBondContact O-NH1 3.14Å
330	L	98.7	Very high	97.8	Very high	1 Å²	1	34.7 Å²	34.7	1%	0.005	17%	0.168	C	C	.	.	H	α-helix	trans	-68.5	-42	172.8	175	61.3	0	0	0	112.5	Y126 M128 S326 Y327 K328 E332 R333 H334 L397 E400	Y126-L330 WeakPolarHBondContact O-CD1 3.29Å; M128-L330 HydrophobicContact CG-CD2 3.99Å; S326-L330 WeakPolarHBondContact O-CB 3.34Å; S326-L330 PolarHBondContact O-N 2.78Å; S326-L330 VanDerWaalsContact O-N 3.11Å; Y327-L330 WeakPolarHBondContact O-CB 3.45Å; Y327-L330 PolarHBondContact O-N 3.31Å; Y327-L330 VanDerWaalsContact O-N 3.16Å; K328-L330 VanDerWaalsContact C-N 3.27Å; K328-L330 PolarHBondContact O-N 3.44Å; L330-E332 VanDerWaalsContact C-N 3.27Å; L330-E332 PolarHBondContact O-N 3.44Å; L330-R333 PolarHBondContact O-N 2.93Å; L330-H334 PolarHBondContact O-N 2.88Å; L330-L397 HydrophobicContact CD2-CD2 3.82Å; L330-L397 HydrophobicContact CD2-CG 4.32Å; L330-L397 HydrophobicContact CG-CD2 3.79Å; L330-L397 HydrophobicContact CG-CG 4.31Å; L330-E400 HydrophobicContact CD2-CB 3.88Å; L330-E400 HydrophobicContact CD2-CG 3.59Å
331	C	98.6	Very high	97.7	Very high	4 Å²	4	41.1 Å²	41.1	3%	0.027	20%	0.196	C	C	.	.	H	α-helix	trans	-55.7	-45	171.2	-66.2	0	0	0	0	111	F218 R222 Y327 K328 R333 H334 E335	F218-C331 HydrophobicContact CE2-CB 4.35Å; F218-C331 HydrophobicContact CZ-CB 4.24Å; R222-C331 HydrophobicContact CG-CB 4.34Å; Y327-C331 WeakPolarHBondContact CE1-SG 3.24Å; Y327-C331 PolarHBondContact O-N 2.76Å; Y327-C331 PolarHBondContact O-SG 3.23Å; K328-C331 WeakPolarHBondContact O-CB 3.34Å; K328-C331 PolarHBondContact O-N 3.12Å; C331-R333 PolarHBondContact O-N 3.43Å; C331-H334 PolarHBondContact O-N 3.13Å; C331-E335 WeakPolarHBondContact O-CG 3.45Å; C331-E335 PolarHBondContact O-N 2.89Å
332	E	98.1	Very high	97.6	Very high	97 Å²	97	41.9 Å²	41.9	45%	0.453	20%	0.199	S	C	.	.	H	α-helix	trans	-63.5	-40.9	176.6	-61.7	-141.5	147.8	0	0	112.7	K328 D329 L330 H334 E335 K336	K328-E332 WeakPolarHBondContact O-CG 3.49Å; K328-E332 PolarHBondContact O-N 3.03Å; D329-E332 PolarHBondContact O-N 3.26Å; L330-E332 VanDerWaalsContact C-N 3.27Å; L330-E332 PolarHBondContact O-N 3.44Å; E332-H334 VanDerWaalsContact C-N 3.32Å; E332-H334 PolarHBondContact O-N 3.02Å; E332-E335 PolarHBondContact O-N 3.28Å; E332-K336 HydrophobicContact CB-CD 4.35Å; E332-K336 WeakPolarHBondContact O-CB 3.25Å; E332-K336 PolarHBondContact O-N 3.39Å; E332-K336 WeakPolarHBondContact OE1-CE 3.47Å; E332-K336 IonicContact OE1-NZ 3.77Å; E332-K336 PolarHBondContact OE1-NZ 2.91Å; E332-K336 WeakPolarHBondContact OE2-CE 3.05Å; E332-K336 IonicContact OE2-NZ 3.61Å; E332-K336 PolarHBondContact OE2-NZ 3.42Å
333	R	97.9	Very high	97.4	Very high	63 Å²	63	44.9 Å²	44.9	24%	0.238	21%	0.211	C	C	.	.	I	π-helix	trans	-60.5	-38.9	173.9	-76.4	-169.7	-67.7	-82.8	10.4	112.3	P125 R127 D329 L330 C331 G337 V338	P125-R333 PolarHBondContact O-NE 2.92Å; R127-R333 PolarHBondContact O-NH2 3.32Å; D329-R333 WeakPolarHBondContact O-CG 3.35Å; D329-R333 PolarHBondContact O-N 2.98Å; D329-R333 PolarHBondContact O-NH1 3.14Å; L330-R333 PolarHBondContact O-N 2.93Å; C331-R333 PolarHBondContact O-N 3.43Å; R333-G337 WeakPolarHBondContact O-CA 3.44Å; R333-G337 PolarHBondContact O-N 3.26Å; R333-V338 PolarHBondContact O-N 3.5Å
334	H	97.8	Very high	97.3	Very high	1 Å²	1	53.2 Å²	53.2	1%	0.005	24%	0.242	C	C	.	.	I	π-helix	trans	-66.1	-57.3	174.3	176.8	69.1	0	0	0	111.5	F218 L330 C331 E332 V338 L339 N390 S393 L397	F218-H334 AromaticContact CE1-CD2 3.99Å; F218-H334 AromaticContact CZ-CD2 3.98Å; L330-H334 PolarHBondContact O-N 2.88Å; C331-H334 PolarHBondContact O-N 3.13Å; E332-H334 VanDerWaalsContact C-N 3.32Å; E332-H334 PolarHBondContact O-N 3.02Å; H334-V338 PolarHBondContact O-N 3.19Å; H334-L339 WeakPolarHBondContact O-CB 3.34Å; H334-L339 PolarHBondContact O-N 3.14Å; H334-N390 PolarHBondContact CE1-OD1 2.75Å; H334-S393 WeakPolarHBondContact ND1-CB 3.49Å; H334-S393 PolarHBondContact ND1-OG 2.91Å; H334-L397 HydrophobicContact CB-CD1 3.63Å
335	E	97.1	Very high	97.1	Very high	60 Å²	60	53.8 Å²	53.8	28%	0.28	25%	0.247	S	C	.	.	I	π-helix	trans	-70.7	-55	-170.3	-66.8	-178.8	92.3	0	0	112.5	F218 R222 C331 E332 G337 H340	F218-E335 HydrophobicContact CE1-CG 4.06Å; F218-E335 HydrophobicContact CZ-CG 4.08Å; R222-E335 IonicContact CZ-OE1 3.28Å; R222-E335 IonicContact CZ-OE2 2.75Å; R222-E335 IonicContact NE-OE2 3.42Å; R222-E335 IonicContact NH1-OE1 2.73Å; R222-E335 PolarHBondContact NH1-OE1 2.68Å; R222-E335 IonicContact NH1-OE2 3.51Å; R222-E335 PolarHBondContact NH1-OE2 2.84Å; R222-E335 IonicContact NH2-OE1 2.68Å; C331-E335 WeakPolarHBondContact O-CG 3.45Å; C331-E335 PolarHBondContact O-N 2.89Å; E332-E335 PolarHBondContact O-N 3.28Å; E335-G337 VanDerWaalsContact C-N 3.31Å; E335-G337 PolarHBondContact O-N 3.13Å; E335-H340 VanDerWaalsContact O-CB 3.28Å; E335-H340 WeakPolarHBondContact O-CB 3.41Å; E335-H340 PolarHBondContact O-N 3.14Å; E335-H340 VanDerWaalsContact O-N 3.14Å
336	K	96.6	Very high	96.9	Very high	132 Å²	132	54.9 Å²	54.9	57%	0.574	25%	0.254	S	S	*	.	I	π-helix	trans	-76.7	-21.9	-177.3	-54.2	178.7	-172.8	173.9	0	112.1	E332 H340	E332-K336 HydrophobicContact CB-CD 4.35Å; E332-K336 WeakPolarHBondContact O-CB 3.25Å; E332-K336 PolarHBondContact O-N 3.39Å; E332-K336 WeakPolarHBondContact OE1-CE 3.47Å; E332-K336 IonicContact OE1-NZ 3.77Å; E332-K336 PolarHBondContact OE1-NZ 2.91Å; E332-K336 WeakPolarHBondContact OE2-CE 3.05Å; E332-K336 IonicContact OE2-NZ 3.61Å; E332-K336 PolarHBondContact OE2-NZ 3.42Å; K336-H340 PolarHBondContact O-ND1 3.29Å
337	G	96.3	Very high	96.8	Very high	21 Å²	21	60.7 Å²	60.7	22%	0.216	28%	0.281	C	S	.	.	I	π-helix	trans	-97.4	-83.4	179.7	0	0	0	0	0	113.3	R333 E335 K341	R333-G337 WeakPolarHBondContact O-CA 3.44Å; R333-G337 PolarHBondContact O-N 3.26Å; E335-G337 VanDerWaalsContact C-N 3.31Å; E335-G337 PolarHBondContact O-N 3.13Å; G337-K341 VanDerWaalsContact O-CB 3.3Å; G337-K341 WeakPolarHBondContact O-CB 3.25Å; G337-K341 WeakPolarHBondContact O-CD 3.39Å; G337-K341 WeakPolarHBondContact O-CG 3.31Å; G337-K341 PolarHBondContact O-N 2.9Å
338	V	95.3	Very high	96.5	Very high	20 Å²	20	65.3 Å²	65.3	12%	0.121	30%	0.301	C	S	.	.	I	π-helix	trans	-68.3	-53.8	-167.4	-166.6	0	0	0	0	112	Y126 R333 H334 K341 H342 R389 N390	Y126-V338 HydrophobicContact CD1-CG2 4.24Å; Y126-V338 HydrophobicContact CE1-CG2 3.71Å; R333-V338 PolarHBondContact O-N 3.5Å; H334-V338 PolarHBondContact O-N 3.19Å; V338-K341 PolarHBondContact O-N 2.99Å; V338-H342 PolarHBondContact O-N 2.73Å; V338-R389 HydrophobicContact CG1-CB 4.38Å; V338-N390 HydrophobicContact CG1-CB 4.24Å
339	L	95.6	Very high	96.3	Very high	31 Å²	31	64.8 Å²	64.8	16%	0.162	30%	0.298	C	S	.	.	I	π-helix	trans	-64.7	-46.5	-176.3	178.6	60.3	0	0	0	111	H334 K341 H342 Q343	H334-L339 WeakPolarHBondContact O-CB 3.34Å; H334-L339 PolarHBondContact O-N 3.14Å; L339-K341 PolarHBondContact O-N 2.94Å; L339-H342 WeakPolarHBondContact O-CB 2.94Å; L339-H342 PolarHBondContact O-N 3.06Å; L339-Q343 HydrophobicContact CD1-CG 4.49Å; L339-Q343 WeakPolarHBondContact O-CG 3.18Å; L339-Q343 PolarHBondContact O-N 2.95Å
340	H	96.3	Very high	96.1	Very high	94 Å²	94	65.8 Å²	65.8	44%	0.435	31%	0.308	S	S	.	.	H	α-helix	trans	-61.5	-38.9	174.7	173.2	-130.1	0	0	0	113	E335 K336 Q343 R344	E335-H340 VanDerWaalsContact O-CB 3.28Å; E335-H340 WeakPolarHBondContact O-CB 3.41Å; E335-H340 PolarHBondContact O-N 3.14Å; E335-H340 VanDerWaalsContact O-N 3.14Å; K336-H340 PolarHBondContact O-ND1 3.29Å; H340-Q343 PolarHBondContact O-N 2.93Å; H340-R344 VanDerWaalsContact O-CB 3.3Å; H340-R344 WeakPolarHBondContact O-CB 3.35Å; H340-R344 PolarHBondContact O-N 2.75Å
341	K	95.6	Very high	95.8	Very high	135 Å²	135	69.2 Å²	69.2	59%	0.587	33%	0.326	S	S	*	.	H	α-helix	trans	-62.2	-43.6	172.7	-79.1	171.2	-176.9	-179	0	111.9	G337 V338 L339 R344 A345 M386	G337-K341 VanDerWaalsContact O-CB 3.3Å; G337-K341 WeakPolarHBondContact O-CB 3.25Å; G337-K341 WeakPolarHBondContact O-CD 3.39Å; G337-K341 WeakPolarHBondContact O-CG 3.31Å; G337-K341 PolarHBondContact O-N 2.9Å; V338-K341 PolarHBondContact O-N 2.99Å; L339-K341 PolarHBondContact O-N 2.94Å; K341-R344 PolarHBondContact O-N 3.49Å; K341-A345 PolarHBondContact O-N 3.5Å; K341-M386 HydrophobicContact CB-SD 4.12Å
342	H	96.1	Very high	95.5	Very high	25 Å²	25	69.3 Å²	69.3	12%	0.116	33%	0.326	C	S	.	.	H	α-helix	trans	-62.3	-47.9	176.4	179.7	-131.8	0	0	0	111.9	V338 L339 R344 A345 L346 M386	V338-H342 PolarHBondContact O-N 2.73Å; L339-H342 WeakPolarHBondContact O-CB 2.94Å; L339-H342 PolarHBondContact O-N 3.06Å; H342-R344 VanDerWaalsContact C-N 3.35Å; H342-R344 PolarHBondContact O-N 3.49Å; H342-A345 WeakPolarHBondContact O-CB 3.41Å; H342-A345 PolarHBondContact O-N 2.94Å; H342-L346 WeakPolarHBondContact O-CG 3.22Å; H342-L346 PolarHBondContact O-N 3.3Å; H342-M386 HydrophobicContact CB-CB 4Å
343	Q	95.9	Very high	95.1	Very high	105 Å²	105	69.5 Å²	69.5	49%	0.491	33%	0.326	S	S	.	.	H	α-helix	trans	-58.9	-42.9	175	-71.3	170.1	-11.8	0	0	112.3	L339 H340 A345 L346 H347	L339-Q343 HydrophobicContact CD1-CG 4.49Å; L339-Q343 WeakPolarHBondContact O-CG 3.18Å; L339-Q343 PolarHBondContact O-N 2.95Å; H340-Q343 PolarHBondContact O-N 2.93Å; Q343-A345 VanDerWaalsContact C-N 3.33Å; Q343-A345 PolarHBondContact O-N 2.74Å; Q343-L346 PolarHBondContact O-N 3.47Å; Q343-H347 PolarHBondContact O-N 3Å
344	R	95.3	Very high	94.8	Very high	186 Å²	186	74.3 Å²	74.3	70%	0.702	34%	0.344	S	S	*	.	H	α-helix	trans	-65.1	-35.3	177.2	-171.1	176.4	-178.1	-169.9	0.4	112.5	H340 K341 H342 K348	H340-R344 VanDerWaalsContact O-CB 3.3Å; H340-R344 WeakPolarHBondContact O-CB 3.35Å; H340-R344 PolarHBondContact O-N 2.75Å; K341-R344 PolarHBondContact O-N 3.49Å; H342-R344 VanDerWaalsContact C-N 3.35Å; H342-R344 PolarHBondContact O-N 3.49Å; R344-K348 WeakPolarHBondContact O-CB 3.42Å; R344-K348 PolarHBondContact O-N 2.9Å
345	A	94.6	Very high	94.4	Very high	12 Å²	12	79.1 Å²	79.1	10%	0.099	37%	0.366	C	S	.	.	H	α-helix	trans	-65.7	-48.1	174.8	0	0	0	0	0	111.7	K341 H342 Q343 H347 K348 Y349 I383	K341-A345 PolarHBondContact O-N 3.5Å; H342-A345 WeakPolarHBondContact O-CB 3.41Å; H342-A345 PolarHBondContact O-N 2.94Å; Q343-A345 VanDerWaalsContact C-N 3.33Å; Q343-A345 PolarHBondContact O-N 2.74Å; A345-H347 VanDerWaalsContact C-N 3.32Å; A345-H347 PolarHBondContact O-N 3.35Å; A345-K348 PolarHBondContact O-N 3.45Å; A345-Y349 PolarHBondContact O-N 2.93Å; A345-I383 HydrophobicContact CB-CG1 3.74Å
346	L	95.1	Very high	93.8	Very high	71 Å²	71	78.9 Å²	78.9	37%	0.372	37%	0.366	S	S	.	.	H	α-helix	trans	-57.6	-43.1	174.3	-69.7	167.3	0	0	0	111.9	H342 Q343 Y349 S350 I383	H342-L346 WeakPolarHBondContact O-CG 3.22Å; H342-L346 PolarHBondContact O-N 3.3Å; Q343-L346 PolarHBondContact O-N 3.47Å; L346-Y349 PolarHBondContact O-N 3.07Å; L346-S350 WeakPolarHBondContact O-CB 3.36Å; L346-S350 PolarHBondContact O-N 2.76Å; L346-S350 PolarHBondContact O-OG 3.42Å; L346-I383 HydrophobicContact CD2-CD1 4.09Å; L346-I383 HydrophobicContact CD2-CG1 4.29Å; L346-I383 HydrophobicContact CD2-CG2 3.75Å; L346-I383 HydrophobicContact CG-CG2 4.45Å
347	H	95.2	Very high	93.3	Very high	122 Å²	122	78.6 Å²	78.6	57%	0.565	37%	0.368	S	S	*	.	H	α-helix	trans	-65.2	-44.2	176.8	-170.7	81	0	0	0	112.4	Q343 A345 Y349 S350 L351	Q343-H347 PolarHBondContact O-N 3Å; A345-H347 VanDerWaalsContact C-N 3.32Å; A345-H347 PolarHBondContact O-N 3.35Å; H347-Y349 PolarHBondContact O-N 3.05Å; H347-S350 WeakPolarHBondContact O-CB 3.46Å; H347-S350 PolarHBondContact O-N 3.03Å; H347-L351 WeakPolarHBondContact O-CG 3.26Å; H347-L351 PolarHBondContact O-N 3.03Å
348	K	94	Very high	92.9	Very high	98 Å²	98	80.2 Å²	80.2	43%	0.426	38%	0.376	S	S	.	.	H	α-helix	trans	-59.1	-45.9	175.7	174.8	166.9	170.8	-108.7	0	111.6	R344 A345 S350 L351 M352 Q379	R344-K348 WeakPolarHBondContact O-CB 3.42Å; R344-K348 PolarHBondContact O-N 2.9Å; A345-K348 PolarHBondContact O-N 3.45Å; K348-S350 VanDerWaalsContact C-N 3.33Å; K348-S350 PolarHBondContact O-N 3.37Å; K348-L351 PolarHBondContact O-N 3.04Å; K348-M352 HydrophobicContact CD-SD 4.24Å; K348-M352 HydrophobicContact CG-CG 4.47Å; K348-M352 HydrophobicContact CG-SD 3.58Å; K348-M352 VanDerWaalsContact CG-SD 3.58Å; K348-M352 VanDerWaalsContact O-CG 3.29Å; K348-M352 WeakPolarHBondContact O-CG 3.46Å; K348-M352 PolarHBondContact O-N 3.43Å; K348-Q379 HydrophobicContact CG-CG 4.46Å
349	Y	93.4	Very high	92.3	Very high	41 Å²	41	79.5 Å²	79.5	16%	0.161	37%	0.373	C	S	.	.	H	α-helix	trans	-56.7	-45.5	173.1	175	-101.2	0	0	0	112.6	A345 L346 H347 L351 M352 K353 I376 Q379 E380 I383	A345-Y349 PolarHBondContact O-N 2.93Å; L346-Y349 PolarHBondContact O-N 3.07Å; H347-Y349 PolarHBondContact O-N 3.05Å; Y349-L351 VanDerWaalsContact C-N 3.27Å; Y349-L351 PolarHBondContact O-N 3.28Å; Y349-M352 PolarHBondContact O-N 2.88Å; Y349-M352 VanDerWaalsContact O-N 3.13Å; Y349-K353 HydrophobicContact CE1-CD 3.94Å; Y349-K353 WeakPolarHBondContact O-CB 3.46Å; Y349-K353 PolarHBondContact O-N 2.91Å; Y349-K353 PolarHBondContact OH-NZ 3.36Å; Y349-I376 HydrophobicContact CD2-CG2 4.25Å; Y349-I376 HydrophobicContact CE2-CG2 3.76Å; Y349-Q379 HydrophobicContact CD2-CG 4.44Å; Y349-E380 HydrophobicContact CD2-CG 3.84Å; Y349-E380 HydrophobicContact CE2-CG 3.33Å; Y349-E380 WeakPolarHBondContact CE2-OE1 3.4Å; Y349-E380 PolarHBondContact OH-OE1 2.81Å; Y349-I383 VanDerWaalsContact CB-CD1 3.47Å; Y349-I383 HydrophobicContact CD1-CD1 4.45Å; Y349-I383 HydrophobicContact CD2-CD1 4.29Å; Y349-I383 HydrophobicContact CG-CD1 3.85Å
350	S	94.1	Very high	91.6	Very high	63 Å²	63	81.1 Å²	81.1	44%	0.441	39%	0.39	S	S	.	.	H	α-helix	trans	-62.3	-34.3	-178.9	-56.5	0	0	0	0	112.5	L346 H347 K348 R354	L346-S350 WeakPolarHBondContact O-CB 3.36Å; L346-S350 PolarHBondContact O-N 2.76Å; L346-S350 PolarHBondContact O-OG 3.42Å; H347-S350 WeakPolarHBondContact O-CB 3.46Å; H347-S350 PolarHBondContact O-N 3.03Å; K348-S350 VanDerWaalsContact C-N 3.33Å; K348-S350 PolarHBondContact O-N 3.37Å; S350-R354 PolarHBondContact O-N 2.74Å
351	L	93.4	Very high	90.9	Very high	72 Å²	72	80.8 Å²	80.8	38%	0.377	40%	0.404	S	S	.	.	H	α-helix	trans	-71.9	-44.6	172.3	-66.9	174.4	0	0	0	112.1	H347 K348 Y349 R354 Q355	H347-L351 WeakPolarHBondContact O-CG 3.26Å; H347-L351 PolarHBondContact O-N 3.03Å; K348-L351 PolarHBondContact O-N 3.04Å; Y349-L351 VanDerWaalsContact C-N 3.27Å; Y349-L351 PolarHBondContact O-N 3.28Å; L351-R354 WeakPolarHBondContact O-CB 3.43Å; L351-R354 PolarHBondContact O-N 3.44Å; L351-Q355 WeakPolarHBondContact O-CG 3.28Å; L351-Q355 PolarHBondContact O-N 3.22Å
352	M	91.9	Very high	90.2	Very high	7 Å²	7	79.9 Å²	79.9	3%	0.034	40%	0.402	C	S	.	.	H	α-helix	trans	-65.4	-40.4	-179.1	-67	167.7	76.3	0	0	111.7	K348 Y349 R354 Q355 M356 R375 I376 Q379	K348-M352 HydrophobicContact CD-SD 4.24Å; K348-M352 HydrophobicContact CG-CG 4.47Å; K348-M352 HydrophobicContact CG-SD 3.58Å; K348-M352 VanDerWaalsContact CG-SD 3.58Å; K348-M352 VanDerWaalsContact O-CG 3.29Å; K348-M352 WeakPolarHBondContact O-CG 3.46Å; K348-M352 PolarHBondContact O-N 3.43Å; Y349-M352 PolarHBondContact O-N 2.88Å; Y349-M352 VanDerWaalsContact O-N 3.13Å; M352-R354 VanDerWaalsContact C-N 3.31Å; M352-R354 PolarHBondContact O-N 2.88Å; M352-Q355 WeakPolarHBondContact O-CB 3.22Å; M352-Q355 PolarHBondContact O-N 3.09Å; M352-M356 PolarHBondContact O-N 3.26Å; M352-R375 HydrophobicContact CE-CB 3.62Å; M352-R375 WeakPolarHBondContact CE-O 3.14Å; M352-I376 HydrophobicContact CB-CD1 4.4Å; M352-I376 HydrophobicContact CB-CG1 3.92Å; M352-I376 HydrophobicContact CE-CG1 4.46Å; M352-Q379 HydrophobicContact SD-CB 4.43Å; M352-Q379 HydrophobicContact SD-CG 4.32Å
353	K	90.1	Very high	89	Confident	100 Å²	100	86 Å²	86	44%	0.435	44%	0.435	S	S	.	.	H	α-helix	trans	-62.4	-36.4	173.1	-165.6	163.4	-166	158.4	0	112.4	Y349 M356 M357	Y349-K353 HydrophobicContact CE1-CD 3.94Å; Y349-K353 WeakPolarHBondContact O-CB 3.46Å; Y349-K353 PolarHBondContact O-N 2.91Å; Y349-K353 PolarHBondContact OH-NZ 3.36Å; K353-M356 PolarHBondContact O-N 3.12Å; K353-M357 WeakPolarHBondContact O-CG 3.36Å; K353-M357 PolarHBondContact O-N 3.33Å; K353-M357 VanDerWaalsContact O-N 3.13Å
354	R	90.8	Very high	87.8	Confident	165 Å²	165	87.9 Å²	87.9	62%	0.623	44%	0.438	S	S	*	.	H	α-helix	trans	-67.6	-40.9	172.7	-168.4	-175	-61	169.6	0.8	112.1	S350 L351 M352 M357 S358	S350-R354 PolarHBondContact O-N 2.74Å; L351-R354 WeakPolarHBondContact O-CB 3.43Å; L351-R354 PolarHBondContact O-N 3.44Å; M352-R354 VanDerWaalsContact C-N 3.31Å; M352-R354 PolarHBondContact O-N 2.88Å; R354-M357 PolarHBondContact O-N 3.37Å; R354-S358 PolarHBondContact O-N 2.89Å; R354-S358 VanDerWaalsContact O-N 3.09Å; R354-S358 PolarHBondContact O-OG 3.19Å
355	Q	89	Confident	86.9	Confident	101 Å²	101	86.5 Å²	86.5	47%	0.472	44%	0.439	S	S	.	.	H	α-helix	trans	-61.3	-44.3	174.4	-72.9	172.4	-21.8	0	0	111.1	L351 M352 S358 A359 L372	L351-Q355 WeakPolarHBondContact O-CG 3.28Å; L351-Q355 PolarHBondContact O-N 3.22Å; M352-Q355 WeakPolarHBondContact O-CB 3.22Å; M352-Q355 PolarHBondContact O-N 3.09Å; Q355-S358 WeakPolarHBondContact CA-OG 3.29Å; Q355-S358 CarbonylContact O-C 3.53Å; Q355-S358 PolarHBondContact O-N 3.03Å; Q355-S358 VanDerWaalsContact O-N 3.14Å; Q355-S358 PolarHBondContact O-OG 3.08Å; Q355-A359 WeakPolarHBondContact O-CB 3.36Å; Q355-A359 PolarHBondContact O-N 3.16Å; Q355-L372 HydrophobicContact CB-CD2 4.21Å
356	M	86.3	Confident	85.9	Confident	56 Å²	56	91.1 Å²	91.1	28%	0.276	47%	0.468	S	S	.	.	H	α-helix	trans	-58.8	-49.6	177	-175.1	-172.7	179.9	0	0	112.1	M352 K353 S358 A359 A360 L372 E373 I376	M352-M356 PolarHBondContact O-N 3.26Å; K353-M356 PolarHBondContact O-N 3.12Å; M356-S358 VanDerWaalsContact C-N 3.26Å; M356-S358 PolarHBondContact O-N 2.87Å; M356-A359 PolarHBondContact O-N 2.69Å; M356-A359 VanDerWaalsContact O-N 3.11Å; M356-A360 PolarHBondContact O-N 3.33Å; M356-L372 HydrophobicContact CB-CD2 3.94Å; M356-L372 HydrophobicContact CB-CG 4.5Å; M356-E373 HydrophobicContact CE-CG 3.54Å; M356-E373 WeakPolarHBondContact CE-OE1 3.3Å; M356-E373 HydrophobicContact SD-CG 4.3Å; M356-I376 HydrophobicContact CB-CD1 3.96Å; M356-I376 HydrophobicContact CG-CD1 4.33Å; M356-I376 HydrophobicContact SD-CD1 3.72Å
357	M	85.9	Confident	84.9	Confident	125 Å²	125	94 Å²	94	62%	0.616	48%	0.48	S	S	*	.	H	α-helix	trans	-57.9	-38.1	175.1	-69	-175.6	-65.9	0	0	112.4	K353 R354 A361	K353-M357 WeakPolarHBondContact O-CG 3.36Å; K353-M357 PolarHBondContact O-N 3.33Å; K353-M357 VanDerWaalsContact O-N 3.13Å; R354-M357 PolarHBondContact O-N 3.37Å; M357-A361 WeakPolarHBondContact O-CB 3.32Å; M357-A361 PolarHBondContact O-N 3.3Å; M357-A361 VanDerWaalsContact O-N 3.17Å
358	S	86.8	Confident	84.2	Confident	55 Å²	55	90.6 Å²	90.6	39%	0.385	47%	0.47	S	S	.	.	H	α-helix	trans	-73.6	-29.5	176	69.8	0	0	0	0	114.3	R354 Q355 M356 Q362	R354-S358 PolarHBondContact O-N 2.89Å; R354-S358 VanDerWaalsContact O-N 3.09Å; R354-S358 PolarHBondContact O-OG 3.19Å; Q355-S358 WeakPolarHBondContact CA-OG 3.29Å; Q355-S358 CarbonylContact O-C 3.53Å; Q355-S358 PolarHBondContact O-N 3.03Å; Q355-S358 VanDerWaalsContact O-N 3.14Å; Q355-S358 PolarHBondContact O-OG 3.08Å; M356-S358 VanDerWaalsContact C-N 3.26Å; M356-S358 PolarHBondContact O-N 2.87Å; S358-Q362 WeakPolarHBondContact O-CB 3.46Å; S358-Q362 WeakPolarHBondContact O-CG 3.37Å; S358-Q362 PolarHBondContact O-N 3.33Å
359	A	83.8	Confident	83.7	Confident	6 Å²	6	87.2 Å²	87.2	5%	0.05	46%	0.457	C	S	.	.	H	α-helix	trans	-73.6	-44.4	177.9	0	0	0	0	0	111.2	Q355 M356 A361 Q362 N363 R364	Q355-A359 WeakPolarHBondContact O-CB 3.36Å; Q355-A359 PolarHBondContact O-N 3.16Å; M356-A359 PolarHBondContact O-N 2.69Å; M356-A359 VanDerWaalsContact O-N 3.11Å; A359-A361 VanDerWaalsContact C-N 3.34Å; A359-A361 PolarHBondContact O-N 3.18Å; A359-Q362 PolarHBondContact O-N 3.36Å; A359-Q362 VanDerWaalsContact O-N 3.09Å; A359-N363 PolarHBondContact O-N 2.76Å; A359-R364 HydrophobicContact CB-CG 4.47Å; A359-R364 PolarHBondContact O-N 2.72Å
360	A	80.1	Confident	83.3	Confident	65 Å²	65	91.7 Å²	91.7	54%	0.537	48%	0.48	S	S	.	.	H	α-helix	trans	-60.9	-41.2	173.4	0	0	0	0	0	111.8	M356 Q362	M356-A360 PolarHBondContact O-N 3.33Å; A360-Q362 PolarHBondContact O-N 3.26Å
361	A	81.4	Confident	83	Confident	87 Å²	87	93.8 Å²	93.8	72%	0.719	48%	0.483	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.5	-8.7	175.1	0	0	0	0	0	114.7	M357 A359	M357-A361 WeakPolarHBondContact O-CB 3.32Å; M357-A361 PolarHBondContact O-N 3.3Å; M357-A361 VanDerWaalsContact O-N 3.17Å; A359-A361 VanDerWaalsContact C-N 3.34Å; A359-A361 PolarHBondContact O-N 3.18Å
362	Q	80.4	Confident	82.7	Confident	115 Å²	115	91.1 Å²	91.1	54%	0.537	47%	0.468	S	S	.	.	T	Hydrogen-bonded Turn	trans	-109.1	3.7	-178.3	-79	-179.2	-4.4	0	0	113.9	S358 A359 A360 R364	S358-Q362 WeakPolarHBondContact O-CB 3.46Å; S358-Q362 WeakPolarHBondContact O-CG 3.37Å; S358-Q362 PolarHBondContact O-N 3.33Å; A359-Q362 PolarHBondContact O-N 3.36Å; A359-Q362 VanDerWaalsContact O-N 3.09Å; A360-Q362 PolarHBondContact O-N 3.26Å; Q362-R364 HydrophobicContact CB-CG 4.07Å; Q362-R364 PolarHBondContact O-N 2.93Å
363	N	71.9	Confident	82.6	Confident	155 Å²	155	95 Å²	95	83%	0.829	49%	0.486	S	S	*	.	T	Hydrogen-bonded Turn	trans	48.7	44.7	-174.1	-68.3	-19.6	0	0	0	112.9	A359	A359-N363 PolarHBondContact O-N 2.76Å
364	R	70.7	Confident	82.6	Confident	144 Å²	144	93.5 Å²	93.5	54%	0.543	49%	0.489	S	S	.	.			trans	-67.6	157.4	174.7	-66.6	-170.2	177.4	-133.5	-4.6	111.4	A359 Q362	A359-R364 HydrophobicContact CB-CG 4.47Å; A359-R364 PolarHBondContact O-N 2.72Å; Q362-R364 HydrophobicContact CB-CG 4.07Å; Q362-R364 PolarHBondContact O-N 2.93Å
365	E	75.8	Confident	82.6	Confident	156 Å²	156	91.4 Å²	91.4	73%	0.729	48%	0.481	S	S	*	.			trans	-54.5	136.2	179.6	-64.8	-179.7	146.9	0	0	111.5	E367 S368 V369	E365-E367 VanDerWaalsContact C-N 3.31Å; E365-E367 PolarHBondContact O-N 3.48Å; E365-S368 WeakPolarHBondContact O-CB 3.36Å; E365-S368 PolarHBondContact O-N 3.45Å; E365-S368 PolarHBondContact O-OG 3.42Å; E365-V369 PolarHBondContact O-N 3.42Å
366	P	74.1	Confident	82.8	Confident	109 Å²	109	87.3 Å²	87.3	71%	0.708	46%	0.462	S	S	*	.	H	α-helix	trans	-61.3	-36.9	-169.6	22.6	-33.4	0	0	0	113	S368 V369 E370	P366-S368 PolarHBondContact O-N 3.19Å; P366-V369 WeakPolarHBondContact O-CA 3.39Å; P366-V369 WeakPolarHBondContact O-CB 3.23Å; P366-V369 PolarHBondContact O-N 3.49Å; P366-E370 PolarHBondContact O-N 2.94Å
367	E	73.6	Confident	83.1	Confident	132 Å²	132	88.5 Å²	88.5	62%	0.617	47%	0.472	S	S	*	.	H	α-helix	trans	-58	-36.3	176.1	-163.7	-171.9	150.6	0	0	111.9	E365 V369 Q371	E365-E367 VanDerWaalsContact C-N 3.31Å; E365-E367 PolarHBondContact O-N 3.48Å; E367-V369 VanDerWaalsContact C-N 3.27Å; E367-V369 PolarHBondContact O-N 3.16Å; E367-Q371 WeakPolarHBondContact O-CB 3.36Å; E367-Q371 WeakPolarHBondContact O-CG 3.38Å; E367-Q371 PolarHBondContact O-N 2.95Å; E367-Q371 PolarHBondContact OE1-NE2 3.39Å
368	S	81.1	Confident	83.4	Confident	50 Å²	50	88.2 Å²	88.2	35%	0.35	47%	0.469	S	S	.	.	H	α-helix	trans	-71.9	-21	176.9	79.1	0	0	0	0	113.7	E365 P366	E365-S368 WeakPolarHBondContact O-CB 3.36Å; E365-S368 PolarHBondContact O-N 3.45Å; E365-S368 PolarHBondContact O-OG 3.42Å; P366-S368 PolarHBondContact O-N 3.19Å
369	V	82.7	Confident	83.7	Confident	27 Å²	27	86.2 Å²	86.2	16%	0.164	45%	0.454	C	S	.	.	H	α-helix	trans	-84.5	-46.8	175.1	-177.3	0	0	0	0	109.8	E365 P366 E367 Q371 L372 E373	E365-V369 PolarHBondContact O-N 3.42Å; P366-V369 WeakPolarHBondContact O-CA 3.39Å; P366-V369 WeakPolarHBondContact O-CB 3.23Å; P366-V369 PolarHBondContact O-N 3.49Å; E367-V369 VanDerWaalsContact C-N 3.27Å; E367-V369 PolarHBondContact O-N 3.16Å; V369-Q371 PolarHBondContact O-N 3Å; V369-L372 CarbonylContact O-C 3.59Å; V369-L372 WeakPolarHBondContact O-CA 3.42Å; V369-L372 WeakPolarHBondContact O-CB 3.22Å; V369-L372 PolarHBondContact O-N 2.97Å; V369-E373 PolarHBondContact O-N 3.39Å
370	E	86.5	Confident	84.2	Confident	135 Å²	135	89.9 Å²	89.9	63%	0.631	47%	0.47	S	S	*	.	H	α-helix	trans	-59.3	-43.5	176.8	-174.4	175	-168.7	0	0	112	P366 L372 E373 S374	P366-E370 PolarHBondContact O-N 2.94Å; E370-L372 PolarHBondContact O-N 3.49Å; E370-E373 PolarHBondContact O-N 2.67Å; E370-S374 PolarHBondContact O-N 2.99Å
371	Q	87.8	Confident	84.9	Confident	108 Å²	108	91 Å²	91	51%	0.505	47%	0.467	S	S	.	.	H	α-helix	trans	-60.2	-31.1	171.8	-72.8	177.1	23.2	0	0	112.8	E367 V369 R375	E367-Q371 WeakPolarHBondContact O-CB 3.36Å; E367-Q371 WeakPolarHBondContact O-CG 3.38Å; E367-Q371 PolarHBondContact O-N 2.95Å; E367-Q371 PolarHBondContact OE1-NE2 3.39Å; V369-Q371 PolarHBondContact O-N 3Å; Q371-R375 WeakPolarHBondContact O-CD 3.34Å; Q371-R375 WeakPolarHBondContact O-CG 3.38Å; Q371-R375 PolarHBondContact O-N 2.97Å
372	L	86.6	Confident	85.4	Confident	15 Å²	15	88.8 Å²	88.8	8%	0.079	45%	0.449	C	S	.	.	H	α-helix	trans	-79.5	-36.6	177.6	-174.4	60.1	0	0	0	111.9	Q355 M356 V369 E370 R375 I376	Q355-L372 HydrophobicContact CB-CD2 4.21Å; M356-L372 HydrophobicContact CB-CD2 3.94Å; M356-L372 HydrophobicContact CB-CG 4.5Å; V369-L372 CarbonylContact O-C 3.59Å; V369-L372 WeakPolarHBondContact O-CA 3.42Å; V369-L372 WeakPolarHBondContact O-CB 3.22Å; V369-L372 PolarHBondContact O-N 2.97Å; E370-L372 PolarHBondContact O-N 3.49Å; L372-R375 PolarHBondContact O-N 3.24Å; L372-I376 HydrophobicContact CG-CD1 4.27Å; L372-I376 VanDerWaalsContact O-CG1 3.29Å; L372-I376 WeakPolarHBondContact O-CG1 3.3Å; L372-I376 PolarHBondContact O-N 3.33Å
373	E	88.6	Confident	86.1	Confident	88 Å²	88	84.2 Å²	84.2	41%	0.411	43%	0.428	S	S	.	.	H	α-helix	trans	-63.4	-48.3	174.3	-73.2	179.3	178.2	0	0	111.8	M356 V369 E370 R375 I376 V377	M356-E373 HydrophobicContact CE-CG 3.54Å; M356-E373 WeakPolarHBondContact CE-OE1 3.3Å; M356-E373 HydrophobicContact SD-CG 4.3Å; V369-E373 PolarHBondContact O-N 3.39Å; E370-E373 PolarHBondContact O-N 2.67Å; E373-R375 VanDerWaalsContact C-N 3.3Å; E373-R375 PolarHBondContact O-N 3.31Å; E373-I376 WeakPolarHBondContact O-CA 3.42Å; E373-I376 WeakPolarHBondContact O-CB 3.43Å; E373-I376 PolarHBondContact O-N 2.96Å; E373-V377 PolarHBondContact O-N 3.05Å
374	S	91.3	Very high	87.3	Confident	69 Å²	69	82.2 Å²	82.2	48%	0.483	41%	0.413	S	S	.	.	H	α-helix	trans	-54.1	-47.3	174.5	-179.8	0	0	0	0	111.7	E370 I376 V377 E378	E370-S374 PolarHBondContact O-N 2.99Å; S374-I376 PolarHBondContact O-N 2.73Å; S374-V377 PolarHBondContact O-N 2.88Å; S374-V377 VanDerWaalsContact O-N 3.15Å; S374-E378 WeakPolarHBondContact O-CG 3.36Å; S374-E378 PolarHBondContact O-N 3.4Å
375	R	91.5	Very high	88.4	Confident	122 Å²	122	78.5 Å²	78.5	46%	0.46	41%	0.407	S	S	.	.	H	α-helix	trans	-67.1	-20.3	176.7	-69.1	168.3	64.5	-139.6	2.1	113.8	M352 Q371 L372 E373 Q379	M352-R375 HydrophobicContact CE-CB 3.62Å; M352-R375 WeakPolarHBondContact CE-O 3.14Å; Q371-R375 WeakPolarHBondContact O-CD 3.34Å; Q371-R375 WeakPolarHBondContact O-CG 3.38Å; Q371-R375 PolarHBondContact O-N 2.97Å; L372-R375 PolarHBondContact O-N 3.24Å; E373-R375 VanDerWaalsContact C-N 3.3Å; E373-R375 PolarHBondContact O-N 3.31Å; R375-Q379 WeakPolarHBondContact O-CB 3.36Å; R375-Q379 PolarHBondContact O-N 3.34Å
376	I	91.8	Very high	89.3	Confident	15 Å²	15	73.1 Å²	73.1	8%	0.077	38%	0.382	C	S	.	.	H	α-helix	trans	-77.7	-43.9	171.5	-75.4	166	0	0	0	110	Y349 M352 M356 L372 E373 S374 Q379 E380	Y349-I376 HydrophobicContact CD2-CG2 4.25Å; Y349-I376 HydrophobicContact CE2-CG2 3.76Å; M352-I376 HydrophobicContact CB-CD1 4.4Å; M352-I376 HydrophobicContact CB-CG1 3.92Å; M352-I376 HydrophobicContact CE-CG1 4.46Å; M356-I376 HydrophobicContact CB-CD1 3.96Å; M356-I376 HydrophobicContact CG-CD1 4.33Å; M356-I376 HydrophobicContact SD-CD1 3.72Å; L372-I376 HydrophobicContact CG-CD1 4.27Å; L372-I376 VanDerWaalsContact O-CG1 3.29Å; L372-I376 WeakPolarHBondContact O-CG1 3.3Å; L372-I376 PolarHBondContact O-N 3.33Å; E373-I376 WeakPolarHBondContact O-CA 3.42Å; E373-I376 WeakPolarHBondContact O-CB 3.43Å; E373-I376 PolarHBondContact O-N 2.96Å; S374-I376 PolarHBondContact O-N 2.73Å; I376-Q379 CarbonylContact O-C 3.57Å; I376-Q379 WeakPolarHBondContact O-CA 3.29Å; I376-Q379 WeakPolarHBondContact O-CB 3.39Å; I376-Q379 PolarHBondContact O-N 3.02Å; I376-E380 PolarHBondContact O-N 3.33Å
377	V	93.1	Very high	90.4	Very high	80 Å²	80	70.6 Å²	70.6	49%	0.485	36%	0.361	S	S	.	.	H	α-helix	trans	-63	-42.8	175.8	176.6	0	0	0	0	111.6	E373 S374 Q379 E380 N381	E373-V377 PolarHBondContact O-N 3.05Å; S374-V377 PolarHBondContact O-N 2.88Å; S374-V377 VanDerWaalsContact O-N 3.15Å; V377-Q379 PolarHBondContact O-N 3.01Å; V377-E380 PolarHBondContact O-N 3Å; V377-N381 PolarHBondContact O-N 2.89Å; V377-N381 VanDerWaalsContact O-N 3.07Å; V377-N381 PolarHBondContact O-ND2 3.5Å
378	E	92.1	Very high	91.5	Very high	120 Å²	120	66.5 Å²	66.5	56%	0.561	34%	0.343	S	S	*	.	H	α-helix	trans	-53.2	-41.7	168.7	-72.7	179.4	166.8	0	0	112	S374 A382	S374-E378 WeakPolarHBondContact O-CG 3.36Å; S374-E378 PolarHBondContact O-N 3.4Å; E378-A382 WeakPolarHBondContact O-CB 3.37Å; E378-A382 PolarHBondContact O-N 2.9Å
379	Q	93.6	Very high	92.3	Very high	12 Å²	12	66 Å²	66	6%	0.056	33%	0.333	C	S	.	.	H	α-helix	trans	-75.2	-31.2	-177.1	-174.4	56.1	77.7	0	0	112.8	K348 Y349 M352 R375 I376 V377 I383	K348-Q379 HydrophobicContact CG-CG 4.46Å; Y349-Q379 HydrophobicContact CD2-CG 4.44Å; M352-Q379 HydrophobicContact SD-CB 4.43Å; M352-Q379 HydrophobicContact SD-CG 4.32Å; R375-Q379 WeakPolarHBondContact O-CB 3.36Å; R375-Q379 PolarHBondContact O-N 3.34Å; I376-Q379 CarbonylContact O-C 3.57Å; I376-Q379 WeakPolarHBondContact O-CA 3.29Å; I376-Q379 WeakPolarHBondContact O-CB 3.39Å; I376-Q379 PolarHBondContact O-N 3.02Å; V377-Q379 PolarHBondContact O-N 3.01Å; Q379-I383 HydrophobicContact CG-CD1 4.39Å; Q379-I383 WeakPolarHBondContact O-CD1 3.15Å; Q379-I383 VanDerWaalsContact O-CG1 3.3Å; Q379-I383 WeakPolarHBondContact O-CG1 3.45Å; Q379-I383 PolarHBondContact O-N 3.24Å
380	E	94	Very high	93	Very high	83 Å²	83	65 Å²	65	39%	0.388	33%	0.327	S	S	.	.	H	α-helix	trans	-67.7	-46.3	171.8	-71.3	-179.2	158	0	0	111	Y349 I376 V377 A382 I383 Q384	Y349-E380 HydrophobicContact CD2-CG 3.84Å; Y349-E380 HydrophobicContact CE2-CG 3.33Å; Y349-E380 WeakPolarHBondContact CE2-OE1 3.4Å; Y349-E380 PolarHBondContact OH-OE1 2.81Å; I376-E380 PolarHBondContact O-N 3.33Å; V377-E380 PolarHBondContact O-N 3Å; E380-A382 VanDerWaalsContact C-N 3.29Å; E380-A382 PolarHBondContact O-N 2.91Å; E380-I383 WeakPolarHBondContact O-CB 3.19Å; E380-I383 PolarHBondContact O-N 3.22Å; E380-Q384 PolarHBondContact O-N 3.16Å
381	N	94	Very high	93.5	Very high	88 Å²	88	61.5 Å²	61.5	47%	0.471	31%	0.309	S	S	.	.	H	α-helix	trans	-58	-40.7	173	-73.5	-50.9	0	0	0	112.3	V377 T385	V377-N381 PolarHBondContact O-N 2.89Å; V377-N381 VanDerWaalsContact O-N 3.07Å; V377-N381 PolarHBondContact O-ND2 3.5Å; N381-T385 WeakPolarHBondContact O-CB 3.45Å; N381-T385 PolarHBondContact O-N 3.08Å; N381-T385 PolarHBondContact O-OG1 3.07Å
382	A	92.6	Very high	94	Very high	41 Å²	41	56.4 Å²	56.4	34%	0.339	29%	0.285	S	S	.	.	H	α-helix	trans	-67	-36.3	174.3	0	0	0	0	0	112.9	E378 E380 M386	E378-A382 WeakPolarHBondContact O-CB 3.37Å; E378-A382 PolarHBondContact O-N 2.9Å; E380-A382 VanDerWaalsContact C-N 3.29Å; E380-A382 PolarHBondContact O-N 2.91Å; A382-M386 VanDerWaalsContact O-CG 3.29Å; A382-M386 WeakPolarHBondContact O-CG 3.45Å; A382-M386 PolarHBondContact O-N 3.4Å; A382-M386 VanDerWaalsContact O-N 3.1Å
383	I	95.9	Very high	94.5	Very high	20 Å²	20	55.7 Å²	55.7	10%	0.103	28%	0.282	C	S	.	.	H	α-helix	trans	-64	-51.7	173.6	-76.7	160.9	0	0	0	110.2	A345 L346 Y349 Q379 E380 T385 M386 E387	A345-I383 HydrophobicContact CB-CG1 3.74Å; L346-I383 HydrophobicContact CD2-CD1 4.09Å; L346-I383 HydrophobicContact CD2-CG1 4.29Å; L346-I383 HydrophobicContact CD2-CG2 3.75Å; L346-I383 HydrophobicContact CG-CG2 4.45Å; Y349-I383 VanDerWaalsContact CB-CD1 3.47Å; Y349-I383 HydrophobicContact CD1-CD1 4.45Å; Y349-I383 HydrophobicContact CD2-CD1 4.29Å; Y349-I383 HydrophobicContact CG-CD1 3.85Å; Q379-I383 HydrophobicContact CG-CD1 4.39Å; Q379-I383 WeakPolarHBondContact O-CD1 3.15Å; Q379-I383 VanDerWaalsContact O-CG1 3.3Å; Q379-I383 WeakPolarHBondContact O-CG1 3.45Å; Q379-I383 PolarHBondContact O-N 3.24Å; E380-I383 WeakPolarHBondContact O-CB 3.19Å; E380-I383 PolarHBondContact O-N 3.22Å; I383-T385 VanDerWaalsContact C-N 3.29Å; I383-T385 PolarHBondContact O-N 3.06Å; I383-M386 CarbonylContact O-C 3.56Å; I383-M386 WeakPolarHBondContact O-CA 3.33Å; I383-M386 PolarHBondContact O-N 3.31Å; I383-E387 PolarHBondContact O-N 3.12Å
384	Q	95.4	Very high	94.9	Very high	112 Å²	112	51.6 Å²	51.6	52%	0.523	26%	0.262	S	S	.	.	H	α-helix	trans	-57.7	-43.3	-179.4	-168.2	-177	37.2	0	0	111.4	E380 M386 E387 L388	E380-Q384 PolarHBondContact O-N 3.16Å; Q384-M386 VanDerWaalsContact C-N 3.32Å; Q384-M386 PolarHBondContact O-N 2.83Å; Q384-E387 PolarHBondContact O-N 3.26Å; Q384-L388 WeakPolarHBondContact O-CG 3.48Å; Q384-L388 PolarHBondContact O-N 3Å
385	T	94.1	Very high	95.2	Very high	66 Å²	66	48.7 Å²	48.7	41%	0.405	24%	0.241	S	C	.	.	H	α-helix	trans	-61.2	-38.5	175.7	-56.3	0	0	0	0	112.3	N381 I383 R389	N381-T385 WeakPolarHBondContact O-CB 3.45Å; N381-T385 PolarHBondContact O-N 3.08Å; N381-T385 PolarHBondContact O-OG1 3.07Å; I383-T385 VanDerWaalsContact C-N 3.29Å; I383-T385 PolarHBondContact O-N 3.06Å; T385-R389 WeakPolarHBondContact O-CB 3.49Å; T385-R389 WeakPolarHBondContact O-CG 3.45Å; T385-R389 PolarHBondContact O-N 3.09Å
386	M	95.7	Very high	95.4	Very high	44 Å²	44	42.9 Å²	42.9	22%	0.217	22%	0.219	C	C	.	.	H	α-helix	trans	-76	-33.2	175.8	-69.1	-60.8	100.1	0	0	113.1	K341 H342 A382 I383 Q384 R389 N390	K341-M386 HydrophobicContact CB-SD 4.12Å; H342-M386 HydrophobicContact CB-CB 4Å; A382-M386 VanDerWaalsContact O-CG 3.29Å; A382-M386 WeakPolarHBondContact O-CG 3.45Å; A382-M386 PolarHBondContact O-N 3.4Å; A382-M386 VanDerWaalsContact O-N 3.1Å; I383-M386 CarbonylContact O-C 3.56Å; I383-M386 WeakPolarHBondContact O-CA 3.33Å; I383-M386 PolarHBondContact O-N 3.31Å; Q384-M386 VanDerWaalsContact C-N 3.32Å; Q384-M386 PolarHBondContact O-N 2.83Å; M386-R389 PolarHBondContact O-N 2.75Å; M386-N390 WeakPolarHBondContact O-CB 3.29Å; M386-N390 PolarHBondContact O-N 3.21Å
387	E	96.3	Very high	95.7	Very high	56 Å²	56	42.3 Å²	42.3	26%	0.262	22%	0.216	S	C	.	.	H	α-helix	trans	-62.9	-49.1	174.8	-171.3	-169.1	168.2	0	0	110.4	K207 I383 Q384 R389 N390 Y391	K207-E387 IonicContact NZ-OE1 2.79Å; K207-E387 PolarHBondContact NZ-OE1 2.96Å; I383-E387 PolarHBondContact O-N 3.12Å; Q384-E387 PolarHBondContact O-N 3.26Å; E387-R389 PolarHBondContact O-N 3.28Å; E387-N390 WeakPolarHBondContact O-CB 3.38Å; E387-N390 PolarHBondContact O-N 3.36Å; E387-N390 VanDerWaalsContact O-N 3.14Å; E387-Y391 HydrophobicContact CG-CD2 3.94Å; E387-Y391 HydrophobicContact CG-CE2 3.63Å; E387-Y391 VanDerWaalsContact O-CD2 3.29Å; E387-Y391 WeakPolarHBondContact O-CD2 3.29Å; E387-Y391 PolarHBondContact O-N 3.05Å; E387-Y391 WeakPolarHBondContact OE1-CE2 3.37Å
388	L	96.9	Very high	95.9	Very high	46 Å²	46	40.3 Å²	40.3	24%	0.241	20%	0.201	C	C	.	.	H	α-helix	trans	-60.4	-45.4	176.7	-66.6	177.8	0	0	0	111.7	F197 T204 Q384 N390 Y391 F392	F197-L388 HydrophobicContact CE2-CB 3.92Å; F197-L388 HydrophobicContact CZ-CB 3.86Å; T204-L388 HydrophobicContact CG2-CD1 4.33Å; T204-L388 WeakPolarHBondContact O-CD2 3.46Å; Q384-L388 WeakPolarHBondContact O-CG 3.48Å; Q384-L388 PolarHBondContact O-N 3Å; L388-N390 VanDerWaalsContact C-N 3.29Å; L388-N390 PolarHBondContact O-N 2.94Å; L388-Y391 PolarHBondContact O-N 3.36Å; L388-F392 WeakPolarHBondContact O-CB 3.39Å; L388-F392 PolarHBondContact O-N 3.34Å
389	R	97.3	Very high	96.1	Very high	38 Å²	38	35.4 Å²	35.4	14%	0.143	18%	0.178	C	C	.	.	H	α-helix	trans	-64.2	-32	174.8	-79.8	176.1	168.4	-97.3	6.2	112.9	Y126 D195 F197 M198 V338 T385 M386 E387 S393	Y126-R389 PolarHBondContact OH-NH1 3.2Å; D195-R389 IonicContact OD1-CZ 3.67Å; D195-R389 IonicContact OD1-NH1 3.23Å; D195-R389 IonicContact OD1-NH2 3.16Å; D195-R389 PolarHBondContact OD1-NH2 2.9Å; D195-R389 VanDerWaalsContact OD1-NH2 3.16Å; D195-R389 IonicContact OD2-CZ 2.71Å; D195-R389 VanDerWaalsContact OD2-CZ 3.23Å; D195-R389 IonicContact OD2-NH1 2.76Å; D195-R389 PolarHBondContact OD2-NH1 3.06Å; D195-R389 IonicContact OD2-NH2 3.72Å; D195-R389 PolarHBondContact OD2-NH2 3.06Å; F197-R389 HydrophobicContact CB-CG 4.38Å; F197-R389 HydrophobicContact CD1-CG 3.77Å; F197-R389 HydrophobicContact CD2-CB 4.32Å; F197-R389 HydrophobicContact CD2-CG 3.47Å; F197-R389 VanDerWaalsContact CD2-CG 3.47Å; F197-R389 HydrophobicContact CE1-CG 3.84Å; F197-R389 HydrophobicContact CE2-CB 4.33Å; F197-R389 HydrophobicContact CE2-CG 3.57Å; F197-R389 HydrophobicContact CG-CG 3.6Å; F197-R389 HydrophobicContact CZ-CG 3.75Å; M198-R389 PolarHBondContact SD-NH2 2.82Å; M198-R389 VanDerWaalsContact SD-NH2 3.43Å; V338-R389 HydrophobicContact CG1-CB 4.38Å; T385-R389 WeakPolarHBondContact O-CB 3.49Å; T385-R389 WeakPolarHBondContact O-CG 3.45Å; T385-R389 PolarHBondContact O-N 3.09Å; M386-R389 PolarHBondContact O-N 2.75Å; E387-R389 PolarHBondContact O-N 3.28Å; R389-S393 VanDerWaalsContact O-CB 3.27Å; R389-S393 WeakPolarHBondContact O-CB 3.49Å; R389-S393 PolarHBondContact O-N 3.38Å
390	N	97.4	Very high	96.3	Very high	7 Å²	7	34.9 Å²	34.9	4%	0.037	18%	0.176	C	C	.	.	H	α-helix	trans	-68.5	-47.5	175.1	-179.9	74.7	0	0	0	111.7	H334 V338 M386 E387 L388 S393 L394	H334-N390 PolarHBondContact CE1-OD1 2.75Å; V338-N390 HydrophobicContact CG1-CB 4.24Å; M386-N390 WeakPolarHBondContact O-CB 3.29Å; M386-N390 PolarHBondContact O-N 3.21Å; E387-N390 WeakPolarHBondContact O-CB 3.38Å; E387-N390 PolarHBondContact O-N 3.36Å; E387-N390 VanDerWaalsContact O-N 3.14Å; L388-N390 VanDerWaalsContact C-N 3.29Å; L388-N390 PolarHBondContact O-N 2.94Å; N390-S393 WeakPolarHBondContact O-CB 3.46Å; N390-S393 PolarHBondContact O-N 3.26Å; N390-L394 WeakPolarHBondContact O-CG 3.21Å; N390-L394 PolarHBondContact O-N 3.5Å; N390-L394 VanDerWaalsContact O-N 3.09Å
391	Y	97.4	Very high	96.4	Very high	61 Å²	61	31.5 Å²	31.5	24%	0.239	16%	0.161	C	C	.	.	H	α-helix	trans	-63.1	-42.7	174.3	-76.2	-64.9	0	0	0	112.4	K207 L210 E387 L388 S393 L394 Y395	K207-Y391 HydrophobicContact CB-CD1 4.29Å; K207-Y391 HydrophobicContact CB-CD2 4.07Å; K207-Y391 HydrophobicContact CB-CE2 4.48Å; K207-Y391 HydrophobicContact CB-CG 3.96Å; K207-Y391 HydrophobicContact CD-CD2 3.82Å; K207-Y391 HydrophobicContact CD-CE1 4.43Å; K207-Y391 HydrophobicContact CD-CE2 3.48Å; K207-Y391 VanDerWaalsContact CD-CE2 3.48Å; K207-Y391 HydrophobicContact CD-CG 4.43Å; K207-Y391 VanDerWaalsContact CE-CE2 3.49Å; K207-Y391 VanDerWaalsContact CE-CZ 3.48Å; K207-Y391 WeakPolarHBondContact CE-OH 3.24Å; K207-Y391 HydrophobicContact CG-CD1 4.1Å; K207-Y391 HydrophobicContact CG-CD2 3.99Å; K207-Y391 HydrophobicContact CG-CE1 4Å; K207-Y391 HydrophobicContact CG-CE2 3.9Å; K207-Y391 HydrophobicContact CG-CG 4.08Å; L210-Y391 HydrophobicContact CD1-CD1 3.8Å; L210-Y391 WeakPolarHBondContact CD1-O 3.46Å; E387-Y391 HydrophobicContact CG-CD2 3.94Å; E387-Y391 HydrophobicContact CG-CE2 3.63Å; E387-Y391 VanDerWaalsContact O-CD2 3.29Å; E387-Y391 WeakPolarHBondContact O-CD2 3.29Å; E387-Y391 PolarHBondContact O-N 3.05Å; E387-Y391 WeakPolarHBondContact OE1-CE2 3.37Å; L388-Y391 PolarHBondContact O-N 3.36Å; Y391-S393 VanDerWaalsContact C-N 3.31Å; Y391-S393 PolarHBondContact O-N 3.22Å; Y391-L394 HydrophobicContact CD1-CD1 4.45Å; Y391-L394 PolarHBondContact O-N 3.22Å; Y391-L394 VanDerWaalsContact O-N 3.14Å; Y391-Y395 PolarHBondContact O-N 3.47Å
392	F	97.7	Very high	96.6	Very high	1 Å²	1	29 Å²	29	0%	0.004	15%	0.146	C	C	.	.	H	α-helix	trans	-64.2	-35.9	175.9	-178.5	-117.5	0	0	0	112.8	Y126 E196 F197 C200 A203 A206 L388 L394 Y395 C396	Y126-F392 AromaticContact CD2-CD1 3.78Å; Y126-F392 HydrophobicContact CD2-CD1 3.78Å; Y126-F392 AromaticContact CD2-CE1 3.65Å; Y126-F392 HydrophobicContact CD2-CE1 3.65Å; Y126-F392 AromaticContact CE2-CD1 3.72Å; Y126-F392 HydrophobicContact CE2-CD1 3.72Å; Y126-F392 AromaticContact CE2-CE1 3.81Å; Y126-F392 HydrophobicContact CE2-CE1 3.81Å; E196-F392 HydrophobicContact CG-CE1 3.91Å; E196-F392 HydrophobicContact CG-CZ 4.27Å; F197-F392 VanDerWaalsContact CA-CE1 3.49Å; F197-F392 HydrophobicContact CB-CD1 3.75Å; F197-F392 HydrophobicContact CB-CE1 3.8Å; F197-F392 HydrophobicContact CD2-CB 3.87Å; F197-F392 AromaticContact CD2-CD1 3.63Å; F197-F392 HydrophobicContact CD2-CD1 3.63Å; F197-F392 HydrophobicContact CD2-CE1 4.41Å; F197-F392 AromaticContact CD2-CG 3.97Å; F197-F392 HydrophobicContact CD2-CG 3.97Å; F197-F392 HydrophobicContact CE2-CB 4.27Å; F197-F392 HydrophobicContact CG-CD1 4.18Å; C200-F392 HydrophobicContact CB-CE2 4Å; C200-F392 HydrophobicContact CB-CZ 3.69Å; A203-F392 HydrophobicContact CB-CB 4.34Å; A203-F392 HydrophobicContact CB-CD1 4Å; A203-F392 HydrophobicContact CB-CD2 3.67Å; A203-F392 HydrophobicContact CB-CE1 4.11Å; A203-F392 HydrophobicContact CB-CE2 3.82Å; A203-F392 HydrophobicContact CB-CG 3.73Å; A203-F392 HydrophobicContact CB-CZ 4.03Å; A206-F392 VanDerWaalsContact CB-CA 3.5Å; A206-F392 HydrophobicContact CB-CB 3.92Å; A206-F392 HydrophobicContact CB-CD2 4.18Å; L388-F392 WeakPolarHBondContact O-CB 3.39Å; L388-F392 PolarHBondContact O-N 3.34Å; F392-L394 VanDerWaalsContact C-N 3.32Å; F392-L394 PolarHBondContact O-N 3.01Å; F392-Y395 HydrophobicContact CD2-CD1 4.01Å; F392-Y395 HydrophobicContact CE2-CD1 4.06Å; F392-Y395 HydrophobicContact CE2-CE1 4.32Å; F392-Y395 PolarHBondContact O-N 3.05Å; F392-C396 PolarHBondContact O-N 2.87Å; F392-C396 PolarHBondContact O-SG 3.19Å
393	S	97.7	Very high	96.8	Very high	1 Å²	1	27.1 Å²	27.1	1%	0.007	13%	0.131	C	C	.	.	H	α-helix	trans	-62.9	-35.9	172.3	-175	0	0	0	0	112.9	Y126 H334 R389 N390 Y391 L397	Y126-S393 WeakPolarHBondContact CD1-OG 3.47Å; H334-S393 WeakPolarHBondContact ND1-CB 3.49Å; H334-S393 PolarHBondContact ND1-OG 2.91Å; R389-S393 VanDerWaalsContact O-CB 3.27Å; R389-S393 WeakPolarHBondContact O-CB 3.49Å; R389-S393 PolarHBondContact O-N 3.38Å; N390-S393 WeakPolarHBondContact O-CB 3.46Å; N390-S393 PolarHBondContact O-N 3.26Å; Y391-S393 VanDerWaalsContact C-N 3.31Å; Y391-S393 PolarHBondContact O-N 3.22Å; S393-L397 WeakPolarHBondContact O-CB 3.36Å; S393-L397 WeakPolarHBondContact O-CG 3.24Å; S393-L397 PolarHBondContact O-N 3.4Å
394	L	97.5	Very high	96.9	Very high	2 Å²	2	26.2 Å²	26.2	1%	0.01	13%	0.126	C	C	.	.	H	α-helix	trans	-71.8	-40.5	175.3	-69.7	164.6	0	0	0	112	L210 I214 F218 N390 Y391 F392 L397 H398	L210-L394 HydrophobicContact CD1-CB 4.07Å; I214-L394 HydrophobicContact CG1-CB 4.18Å; I214-L394 HydrophobicContact CG2-CD1 4.46Å; F218-L394 HydrophobicContact CB-CD2 4.46Å; F218-L394 HydrophobicContact CG-CD2 4.47Å; N390-L394 WeakPolarHBondContact O-CG 3.21Å; N390-L394 PolarHBondContact O-N 3.5Å; N390-L394 VanDerWaalsContact O-N 3.09Å; Y391-L394 HydrophobicContact CD1-CD1 4.45Å; Y391-L394 PolarHBondContact O-N 3.22Å; Y391-L394 VanDerWaalsContact O-N 3.14Å; F392-L394 VanDerWaalsContact C-N 3.32Å; F392-L394 PolarHBondContact O-N 3.01Å; L394-L397 WeakPolarHBondContact O-CB 3.44Å; L394-L397 PolarHBondContact O-N 2.87Å; L394-H398 WeakPolarHBondContact O-CB 3.22Å; L394-H398 PolarHBondContact O-N 2.98Å
395	Y	96.7	Very high	96.9	Very high	7 Å²	7	24.9 Å²	24.9	3%	0.027	12%	0.12	C	C	.	.	H	α-helix	trans	-59.1	-45.5	172.7	169.3	-83.2	0	0	0	111.5	P61 L62 A206 F209 Y391 F392 H398 Q399	P61-Y395 PolarHBondContact O-OH 3.05Å; L62-Y395 HydrophobicContact CD1-CD2 3.78Å; L62-Y395 HydrophobicContact CD1-CE2 4.2Å; A206-Y395 HydrophobicContact CB-CG 4.34Å; F209-Y395 HydrophobicContact CB-CD2 4.39Å; F209-Y395 HydrophobicContact CB-CE2 4.33Å; F209-Y395 HydrophobicContact CD2-CE2 4.44Å; Y391-Y395 PolarHBondContact O-N 3.47Å; F392-Y395 HydrophobicContact CD2-CD1 4.01Å; F392-Y395 HydrophobicContact CE2-CD1 4.06Å; F392-Y395 HydrophobicContact CE2-CE1 4.32Å; F392-Y395 PolarHBondContact O-N 3.05Å; Y395-H398 PolarHBondContact O-N 3.34Å; Y395-Q399 PolarHBondContact O-N 3.19Å; Y395-Q399 PolarHBondContact OH-NE2 3Å
396	C	97	Very high	97.1	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-62.9	-50.9	174.1	-62.2	0	0	0	0	110.7	Y126 R127 F392 H398 Q399 E400	Y126-C396 WeakPolarHBondContact O-CB 3.27Å; R127-C396 PolarHBondContact NH2-SG 2.91Å; F392-C396 PolarHBondContact O-N 2.87Å; F392-C396 PolarHBondContact O-SG 3.19Å; C396-H398 PolarHBondContact O-N 3.42Å; C396-H398 VanDerWaalsContact O-N 3.17Å; C396-Q399 CarbonylContact O-C 3.53Å; C396-Q399 WeakPolarHBondContact O-CA 3.32Å; C396-Q399 WeakPolarHBondContact O-CB 3.46Å; C396-Q399 PolarHBondContact O-N 3.05Å; C396-E400 WeakPolarHBondContact O-CG 3.34Å; C396-E400 PolarHBondContact O-N 3.47Å
397	L	97.3	Very high	97.2	Very high	3 Å²	3	21 Å²	21	2%	0.016	10%	0.098	C	C	.	.	H	α-helix	trans	-51.4	-39.1	175.4	-93.2	165	0	0	0	113.8	F218 Y327 L330 H334 S393 L394 E400 T401	F218-L397 HydrophobicContact CD2-CD1 3.79Å; F218-L397 HydrophobicContact CD2-CD2 4.23Å; F218-L397 HydrophobicContact CD2-CG 4.45Å; F218-L397 HydrophobicContact CE2-CD1 3.5Å; F218-L397 HydrophobicContact CE2-CD2 3.82Å; F218-L397 HydrophobicContact CE2-CG 4.26Å; F218-L397 HydrophobicContact CZ-CD1 4.18Å; Y327-L397 HydrophobicContact CE2-CD2 4.24Å; L330-L397 HydrophobicContact CD2-CD2 3.82Å; L330-L397 HydrophobicContact CD2-CG 4.32Å; L330-L397 HydrophobicContact CG-CD2 3.79Å; L330-L397 HydrophobicContact CG-CG 4.31Å; H334-L397 HydrophobicContact CB-CD1 3.63Å; S393-L397 WeakPolarHBondContact O-CB 3.36Å; S393-L397 WeakPolarHBondContact O-CG 3.24Å; S393-L397 PolarHBondContact O-N 3.4Å; L394-L397 WeakPolarHBondContact O-CB 3.44Å; L394-L397 PolarHBondContact O-N 2.87Å; L397-E400 PolarHBondContact O-N 2.97Å; L397-T401 WeakPolarHBondContact O-CB 3.22Å; L397-T401 PolarHBondContact O-N 3.26Å; L397-T401 PolarHBondContact O-OG1 3.23Å
398	H	96.6	Very high	97.2	Very high	38 Å²	38	20.8 Å²	20.8	18%	0.176	10%	0.098	C	C	.	.	H	α-helix	trans	-68.9	-36.5	177.1	-172.1	92.8	0	0	0	112.4	L62 I214 L394 Y395 C396 Q402	L62-H398 HydrophobicContact CD1-CB 4.46Å; I214-H398 HydrophobicContact CD1-CB 4.18Å; L394-H398 WeakPolarHBondContact O-CB 3.22Å; L394-H398 PolarHBondContact O-N 2.98Å; Y395-H398 PolarHBondContact O-N 3.34Å; C396-H398 PolarHBondContact O-N 3.42Å; C396-H398 VanDerWaalsContact O-N 3.17Å; H398-Q402 PolarHBondContact CD2-NE2 2.87Å; H398-Q402 PolarHBondContact O-N 2.9Å; H398-Q402 PolarHBondContact O-NE2 3.02Å
399	Q	96.3	Very high	97.1	Very high	17 Å²	17	21.7 Å²	21.7	8%	0.079	11%	0.107	C	C	.	.	H	α-helix	trans	-65.8	-45.9	169.8	-69.5	-177.2	-30.1	0	0	111.5	P61 L64 Y395 C396 T401 Q402 L403	P61-Q399 PolarHBondContact O-NE2 2.94Å; L64-Q399 HydrophobicContact CD1-CB 3.95Å; L64-Q399 WeakPolarHBondContact CD1-O 3.43Å; L64-Q399 HydrophobicContact CG-CB 4.03Å; L64-Q399 HydrophobicContact CG-CG 4.24Å; Y395-Q399 PolarHBondContact O-N 3.19Å; Y395-Q399 PolarHBondContact OH-NE2 3Å; C396-Q399 CarbonylContact O-C 3.53Å; C396-Q399 WeakPolarHBondContact O-CA 3.32Å; C396-Q399 WeakPolarHBondContact O-CB 3.46Å; C396-Q399 PolarHBondContact O-N 3.05Å; Q399-T401 VanDerWaalsContact C-N 3.29Å; Q399-T401 PolarHBondContact O-N 3.12Å; Q399-Q402 WeakPolarHBondContact O-CB 3.4Å; Q399-Q402 PolarHBondContact O-N 3.18Å; Q399-L403 PolarHBondContact O-N 3.33Å
400	E	97.8	Very high	97	Very high	1 Å²	1	20.4 Å²	20.4	1%	0.005	10%	0.102	C	C	.	.	H	α-helix	trans	-64.9	-33.1	178.7	-58	-57.8	106.9	0	0	112.2	R127 M128 H162 L330 C396 L397 L403 I404	R127-E400 VanDerWaalsContact CD-CD 3.46Å; R127-E400 WeakPolarHBondContact CD-OE1 3.49Å; R127-E400 IonicContact CZ-OE1 3.16Å; R127-E400 IonicContact NE-OE1 3.71Å; R127-E400 IonicContact NH1-OE1 3.22Å; R127-E400 PolarHBondContact NH1-OE1 3.07Å; M128-E400 WeakPolarHBondContact CB-OE2 3.42Å; M128-E400 HydrophobicContact CE-CB 3.93Å; M128-E400 WeakPolarHBondContact CE-O 3.49Å; M128-E400 HydrophobicContact CG-CB 3.95Å; M128-E400 HydrophobicContact CG-CG 4.18Å; M128-E400 WeakPolarHBondContact CG-OE2 3.41Å; M128-E400 PolarHBondContact N-OE2 2.77Å; M128-E400 HydrophobicContact SD-CB 4.1Å; H162-E400 IonicContact CE1-OE1 3.56Å; H162-E400 IonicContact CE1-OE2 2.74Å; H162-E400 IonicContact NE2-OE1 3.46Å; H162-E400 PolarHBondContact NE2-OE1 2.89Å; H162-E400 IonicContact NE2-OE2 2.88Å; H162-E400 PolarHBondContact NE2-OE2 2.71Å; H162-E400 VanDerWaalsContact NE2-OE2 3.08Å; L330-E400 HydrophobicContact CD2-CB 3.88Å; L330-E400 HydrophobicContact CD2-CG 3.59Å; C396-E400 WeakPolarHBondContact O-CG 3.34Å; C396-E400 PolarHBondContact O-N 3.47Å; L397-E400 PolarHBondContact O-N 2.97Å; E400-L403 WeakPolarHBondContact O-CB 3.31Å; E400-L403 PolarHBondContact O-N 3.09Å; E400-I404 PolarHBondContact O-N 3.38Å
401	T	97.6	Very high	96.9	Very high	12 Å²	12	21.9 Å²	21.9	7%	0.074	11%	0.112	C	C	.	.	H	α-helix	trans	-61.1	-48.6	171.6	-61.1	0	0	0	0	111.1	I225 Y327 L397 Q399 L403 I404 H405	I225-T401 HydrophobicContact CD1-CG2 4.36Å; Y327-T401 WeakPolarHBondContact CE2-OG1 3.46Å; Y327-T401 PolarHBondContact OH-OG1 2.94Å; L397-T401 WeakPolarHBondContact O-CB 3.22Å; L397-T401 PolarHBondContact O-N 3.26Å; L397-T401 PolarHBondContact O-OG1 3.23Å; Q399-T401 VanDerWaalsContact C-N 3.29Å; Q399-T401 PolarHBondContact O-N 3.12Å; T401-L403 PolarHBondContact O-N 3.39Å; T401-I404 WeakPolarHBondContact O-CB 3.15Å; T401-I404 PolarHBondContact O-N 2.79Å; T401-I404 VanDerWaalsContact O-N 3.16Å; T401-H405 PolarHBondContact O-CD2 2.67Å; T401-H405 PolarHBondContact O-N 3.45Å; T401-H405 VanDerWaalsContact O-N 3.14Å
402	Q	96.7	Very high	96.9	Very high	35 Å²	35	22.5 Å²	22.5	16%	0.164	13%	0.125	C	C	.	.	H	α-helix	trans	-58.2	-40	174	-71.1	165.5	79.2	0	0	111.2	L62 L63 H398 Q399 I404 H405 V406	L62-Q402 PolarHBondContact O-NE2 3.38Å; L63-Q402 VanDerWaalsContact CA-OE1 3.3Å; H398-Q402 PolarHBondContact CD2-NE2 2.87Å; H398-Q402 PolarHBondContact O-N 2.9Å; H398-Q402 PolarHBondContact O-NE2 3.02Å; Q399-Q402 WeakPolarHBondContact O-CB 3.4Å; Q399-Q402 PolarHBondContact O-N 3.18Å; Q402-I404 VanDerWaalsContact C-N 3.34Å; Q402-I404 PolarHBondContact O-N 3.27Å; Q402-H405 CarbonylContact O-C 3.51Å; Q402-H405 WeakPolarHBondContact O-CA 3.23Å; Q402-H405 WeakPolarHBondContact O-CB 3.35Å; Q402-H405 PolarHBondContact O-N 3.4Å; Q402-V406 WeakPolarHBondContact O-CG2 3.3Å; Q402-V406 PolarHBondContact O-N 3.01Å
403	L	97.3	Very high	96.8	Very high	3 Å²	3	26.6 Å²	26.6	2%	0.016	14%	0.144	C	C	.	.	H	α-helix	trans	-60.8	-40.3	176.9	-170.7	58.1	0	0	0	112.1	L64 L71 M128 H162 P163 Q399 E400 T401 H405 V406 Y407	L64-L403 HydrophobicContact CD1-CB 4.35Å; L71-L403 HydrophobicContact CD1-CD1 3.41Å; L71-L403 VanDerWaalsContact CD1-CD1 3.41Å; M128-L403 HydrophobicContact CE-CB 3.9Å; M128-L403 HydrophobicContact CE-CD2 3.72Å; M128-L403 HydrophobicContact CE-CG 3.95Å; H162-L403 WeakPolarHBondContact CD2-CD2 3.25Å; H162-L403 WeakPolarHBondContact NE2-CD2 3.27Å; P163-L403 HydrophobicContact CG-CD1 4.03Å; P163-L403 HydrophobicContact CG-CD2 4.29Å; Q399-L403 PolarHBondContact O-N 3.33Å; E400-L403 WeakPolarHBondContact O-CB 3.31Å; E400-L403 PolarHBondContact O-N 3.09Å; T401-L403 PolarHBondContact O-N 3.39Å; L403-H405 VanDerWaalsContact C-N 3.32Å; L403-H405 PolarHBondContact O-N 3.02Å; L403-V406 PolarHBondContact O-N 2.69Å; L403-Y407 HydrophobicContact CD1-CD2 4.34Å; L403-Y407 HydrophobicContact CD1-CE2 4.08Å; L403-Y407 HydrophobicContact CG-CD2 4.44Å; L403-Y407 HydrophobicContact CG-CE2 4.35Å; L403-Y407 WeakPolarHBondContact O-CD2 3.3Å; L403-Y407 PolarHBondContact O-N 3.48Å
404	I	98	Very high	96.7	Very high	1 Å²	1	26.8 Å²	26.8	1%	0.005	15%	0.145	C	C	.	.	H	α-helix	trans	-58.4	-43.1	170	-64.5	-59.6	0	0	0	111.5	M128 I225 L323 L324 Y327 E400 T401 Q402 V406 Y407 L408	M128-I404 HydrophobicContact CE-CD1 3.97Å; M128-I404 HydrophobicContact CE-CG1 4.16Å; M128-I404 HydrophobicContact SD-CD1 3.61Å; M128-I404 HydrophobicContact SD-CG1 3.86Å; I225-I404 HydrophobicContact CD1-CB 4.19Å; I225-I404 HydrophobicContact CD1-CG1 4.19Å; I225-I404 HydrophobicContact CD1-CG2 4.03Å; I225-I404 HydrophobicContact CG1-CG2 4.1Å; L323-I404 HydrophobicContact CD1-CD1 3.94Å; L323-I404 HydrophobicContact CD2-CD1 4.01Å; L323-I404 HydrophobicContact CG-CD1 3.58Å; L324-I404 HydrophobicContact CD2-CD1 4.4Å; L324-I404 HydrophobicContact CD2-CG2 3.91Å; Y327-I404 HydrophobicContact CD2-CG1 3.94Å; Y327-I404 HydrophobicContact CG-CG1 4.21Å; E400-I404 PolarHBondContact O-N 3.38Å; T401-I404 WeakPolarHBondContact O-CB 3.15Å; T401-I404 PolarHBondContact O-N 2.79Å; T401-I404 VanDerWaalsContact O-N 3.16Å; Q402-I404 VanDerWaalsContact C-N 3.34Å; Q402-I404 PolarHBondContact O-N 3.27Å; I404-V406 PolarHBondContact O-N 2.87Å; I404-Y407 PolarHBondContact O-N 3.45Å; I404-Y407 VanDerWaalsContact O-N 3.11Å; I404-L408 PolarHBondContact O-N 3.37Å
405	H	96.3	Very high	96.7	Very high	83 Å²	83	31 Å²	31	38%	0.384	17%	0.167	S	C	.	.	H	α-helix	trans	-64	-36.7	176.6	-73.8	-77.4	0	0	0	113	T401 Q402 L403 Y407 L408	T401-H405 PolarHBondContact O-CD2 2.67Å; T401-H405 PolarHBondContact O-N 3.45Å; T401-H405 VanDerWaalsContact O-N 3.14Å; Q402-H405 CarbonylContact O-C 3.51Å; Q402-H405 WeakPolarHBondContact O-CA 3.23Å; Q402-H405 WeakPolarHBondContact O-CB 3.35Å; Q402-H405 PolarHBondContact O-N 3.4Å; L403-H405 VanDerWaalsContact C-N 3.32Å; L403-H405 PolarHBondContact O-N 3.02Å; H405-Y407 PolarHBondContact O-N 3.08Å; H405-L408 HydrophobicContact CB-CD1 4.3Å; H405-L408 VanDerWaalsContact ND1-CD1 3.31Å; H405-L408 WeakPolarHBondContact ND1-CD1 3.07Å; H405-L408 WeakPolarHBondContact O-CB 3.35Å; H405-L408 PolarHBondContact O-N 3.16Å
406	V	97.2	Very high	96.7	Very high	23 Å²	23	38.9 Å²	38.9	14%	0.139	20%	0.197	C	C	.	.	H	α-helix	trans	-62.6	-29.2	173.1	178.8	0	0	0	0	111.8	H66 L68 L71 Q402 L403 I404 P409	H66-V406 VanDerWaalsContact O-CG1 3.28Å; H66-V406 WeakPolarHBondContact O-CG1 3.47Å; H66-V406 VanDerWaalsContact O-CG2 3.24Å; H66-V406 WeakPolarHBondContact O-CG2 3.39Å; L68-V406 WeakPolarHBondContact CB-O 3.38Å; L71-V406 HydrophobicContact CD1-CB 4.29Å; L71-V406 HydrophobicContact CD1-CG1 3.56Å; L71-V406 HydrophobicContact CG-CG1 4.35Å; Q402-V406 WeakPolarHBondContact O-CG2 3.3Å; Q402-V406 PolarHBondContact O-N 3.01Å; L403-V406 PolarHBondContact O-N 2.69Å; I404-V406 PolarHBondContact O-N 2.87Å; V406-P409 WeakPolarHBondContact O-CD 3.48Å
407	Y	97.6	Very high	96.7	Very high	7 Å²	7	39.4 Å²	39.4	3%	0.027	20%	0.201	C	C	.	.	H	α-helix	trans	-84	-14	175.4	-84.1	-84	0	0	0	115.1	L68 L71 L323 L403 I404 H405 L410	L68-Y407 HydrophobicContact CD1-CD1 3.58Å; L68-Y407 HydrophobicContact CD1-CE1 3.81Å; L68-Y407 HydrophobicContact CD1-CG 4.22Å; L71-Y407 HydrophobicContact CD1-CD2 4.23Å; L71-Y407 HydrophobicContact CD1-CE2 3.65Å; L323-Y407 HydrophobicContact CD2-CD1 3.92Å; L323-Y407 HydrophobicContact CD2-CD2 3.45Å; L323-Y407 VanDerWaalsContact CD2-CD2 3.45Å; L323-Y407 HydrophobicContact CD2-CE1 4.49Å; L323-Y407 HydrophobicContact CD2-CE2 4.08Å; L323-Y407 HydrophobicContact CD2-CG 3.36Å; L403-Y407 HydrophobicContact CD1-CD2 4.34Å; L403-Y407 HydrophobicContact CD1-CE2 4.08Å; L403-Y407 HydrophobicContact CG-CD2 4.44Å; L403-Y407 HydrophobicContact CG-CE2 4.35Å; L403-Y407 WeakPolarHBondContact O-CD2 3.3Å; L403-Y407 PolarHBondContact O-N 3.48Å; I404-Y407 PolarHBondContact O-N 3.45Å; I404-Y407 VanDerWaalsContact O-N 3.11Å; H405-Y407 PolarHBondContact O-N 3.08Å; Y407-L410 WeakPolarHBondContact O-CB 3.39Å; Y407-L410 PolarHBondContact O-N 3.22Å
408	L	96.1	Very high	96.6	Very high	51 Å²	51	42.2 Å²	42.2	27%	0.267	21%	0.213	S	C	.	.	T	Hydrogen-bonded Turn	trans	-53.6	-36.7	179.5	-75.3	169.9	0	0	0	115.4	I228 F320 I404 H405 L410 T411	I228-L408 HydrophobicContact CD1-CD2 4.32Å; F320-L408 HydrophobicContact CZ-CD2 4.03Å; I404-L408 PolarHBondContact O-N 3.37Å; H405-L408 HydrophobicContact CB-CD1 4.3Å; H405-L408 VanDerWaalsContact ND1-CD1 3.31Å; H405-L408 WeakPolarHBondContact ND1-CD1 3.07Å; H405-L408 WeakPolarHBondContact O-CB 3.35Å; H405-L408 PolarHBondContact O-N 3.16Å; L408-L410 PolarHBondContact O-N 3.05Å; L408-L410 VanDerWaalsContact O-N 3.08Å; L408-T411 VanDerWaalsContact O-CB 3.25Å; L408-T411 WeakPolarHBondContact O-CB 3.39Å; L408-T411 PolarHBondContact O-N 3.41Å; L408-T411 PolarHBondContact O-OG1 3.41Å
409	P	96.3	Very high	96.7	Very high	65 Å²	65	44 Å²	44	42%	0.422	23%	0.227	S	C	.	.	T	Hydrogen-bonded Turn	trans	-61.6	-14.6	176.3	-23.7	35.3	0	0	0	114.6	L68 V406 T411 S412	L68-P409 HydrophobicContact CD2-CB 3.93Å; V406-P409 WeakPolarHBondContact O-CD 3.48Å; P409-T411 PolarHBondContact O-N 3.34Å; P409-T411 VanDerWaalsContact O-N 3.16Å; P409-S412 WeakPolarHBondContact O-CB 3.14Å; P409-S412 PolarHBondContact O-N 3Å
410	L	95.4	Very high	96.7	Very high	10 Å²	10	47.6 Å²	47.6	5%	0.052	25%	0.247	C	C	.	.	H	α-helix	trans	-57.3	-26.2	170.2	-171.3	63.9	0	0	0	111.8	L68 F320 Y407 L408 S412 H413 I414	L68-L410 HydrophobicContact CD2-CB 4.27Å; F320-L410 HydrophobicContact CB-CD2 3.99Å; F320-L410 HydrophobicContact CD2-CD2 4.29Å; F320-L410 HydrophobicContact CG-CD2 4.37Å; Y407-L410 WeakPolarHBondContact O-CB 3.39Å; Y407-L410 PolarHBondContact O-N 3.22Å; L408-L410 PolarHBondContact O-N 3.05Å; L408-L410 VanDerWaalsContact O-N 3.08Å; L410-S412 VanDerWaalsContact C-N 3.29Å; L410-S412 PolarHBondContact O-N 3.45Å; L410-H413 HydrophobicContact CD1-CB 4.2Å; L410-H413 WeakPolarHBondContact O-CB 3.44Å; L410-H413 PolarHBondContact O-N 3.49Å; L410-I414 HydrophobicContact CG-CD1 4.14Å; L410-I414 HydrophobicContact CG-CG1 4.48Å; L410-I414 WeakPolarHBondContact O-CG1 3.3Å; L410-I414 PolarHBondContact O-N 2.63Å
411	T	95.6	Very high	96.5	Very high	39 Å²	39	48 Å²	48	24%	0.239	25%	0.249	C	C	.	.	H	α-helix	trans	-50.7	-47.2	169	-51.9	0	0	0	0	111.9	F232 L408 P409 H413 I414 L415	F232-T411 HydrophobicContact CE1-CG2 4.35Å; F232-T411 HydrophobicContact CZ-CG2 3.82Å; F232-T411 WeakPolarHBondContact CZ-OG1 3.41Å; L408-T411 VanDerWaalsContact O-CB 3.25Å; L408-T411 WeakPolarHBondContact O-CB 3.39Å; L408-T411 PolarHBondContact O-N 3.41Å; L408-T411 PolarHBondContact O-OG1 3.41Å; P409-T411 PolarHBondContact O-N 3.34Å; P409-T411 VanDerWaalsContact O-N 3.16Å; T411-H413 VanDerWaalsContact C-N 3.3Å; T411-H413 PolarHBondContact O-N 3.01Å; T411-I414 PolarHBondContact O-N 3.33Å; T411-L415 HydrophobicContact CG2-CD1 4.13Å; T411-L415 WeakPolarHBondContact O-CG 3.36Å; T411-L415 PolarHBondContact O-N 3.27Å
412	S	96.3	Very high	96.5	Very high	73 Å²	73	49.2 Å²	49.2	51%	0.51	25%	0.254	S	S	.	.	H	α-helix	trans	-68.7	-29.7	179.8	-56.4	0	0	0	0	112.1	P409 L410 R416	P409-S412 WeakPolarHBondContact O-CB 3.14Å; P409-S412 PolarHBondContact O-N 3Å; L410-S412 VanDerWaalsContact C-N 3.29Å; L410-S412 PolarHBondContact O-N 3.45Å; S412-R416 VanDerWaalsContact O-CB 3.22Å; S412-R416 WeakPolarHBondContact O-CB 3.03Å; S412-R416 PolarHBondContact O-N 2.81Å
413	H	95.5	Very high	96.5	Very high	88 Å²	88	52.5 Å²	52.5	41%	0.407	27%	0.272	S	S	.	.	H	α-helix	trans	-73.7	-39.8	174.2	-60.2	172.5	0	0	0	111.6	L410 T411 R416 A417	L410-H413 HydrophobicContact CD1-CB 4.2Å; L410-H413 WeakPolarHBondContact O-CB 3.44Å; L410-H413 PolarHBondContact O-N 3.49Å; T411-H413 VanDerWaalsContact C-N 3.3Å; T411-H413 PolarHBondContact O-N 3.01Å; H413-R416 PolarHBondContact O-N 2.65Å; H413-A417 VanDerWaalsContact O-CB 3.32Å; H413-A417 WeakPolarHBondContact O-CB 3.45Å; H413-A417 PolarHBondContact O-N 3.19Å
414	I	96.3	Very high	96.4	Very high	4 Å²	4	56.6 Å²	56.6	2%	0.021	29%	0.291	C	S	.	.	H	α-helix	trans	-62.4	-49.3	174.6	-69.6	158.9	0	0	0	110.5	F232 V313 K316 L317 L410 T411 R416 A417 F418	F232-I414 HydrophobicContact CE1-CD1 4.4Å; V313-I414 HydrophobicContact CG1-CG2 4.37Å; K316-I414 HydrophobicContact CB-CD1 4.49Å; K316-I414 HydrophobicContact CB-CG1 3.7Å; L317-I414 HydrophobicContact CD1-CG2 4.24Å; L317-I414 HydrophobicContact CD2-CD1 4.14Å; L317-I414 HydrophobicContact CD2-CG2 3.83Å; L317-I414 HydrophobicContact CG-CD1 4.41Å; L317-I414 HydrophobicContact CG-CG2 3.77Å; L410-I414 HydrophobicContact CG-CD1 4.14Å; L410-I414 HydrophobicContact CG-CG1 4.48Å; L410-I414 WeakPolarHBondContact O-CG1 3.3Å; L410-I414 PolarHBondContact O-N 2.63Å; T411-I414 PolarHBondContact O-N 3.33Å; I414-R416 PolarHBondContact O-N 2.97Å; I414-A417 PolarHBondContact O-N 2.84Å; I414-F418 PolarHBondContact O-N 3.37Å
415	L	96.4	Very high	96.2	Very high	91 Å²	91	57 Å²	57	48%	0.476	30%	0.295	S	S	.	.	H	α-helix	trans	-63.4	-41.4	178.5	-69.1	172.7	0	0	0	111.9	T411 F418 V419	T411-L415 HydrophobicContact CG2-CD1 4.13Å; T411-L415 WeakPolarHBondContact O-CG 3.36Å; T411-L415 PolarHBondContact O-N 3.27Å; L415-F418 PolarHBondContact O-N 2.96Å; L415-V419 WeakPolarHBondContact O-CG2 3.34Å; L415-V419 PolarHBondContact O-N 3.09Å
416	R	97.3	Very high	96.1	Very high	172 Å²	172	58.4 Å²	58.4	65%	0.649	30%	0.302	S	S	*	.	H	α-helix	trans	-62.6	-43.8	174.3	-174.3	-175.2	-62.9	-90.9	3.8	112	S412 H413 I414 V419 N420	S412-R416 VanDerWaalsContact O-CB 3.22Å; S412-R416 WeakPolarHBondContact O-CB 3.03Å; S412-R416 PolarHBondContact O-N 2.81Å; H413-R416 PolarHBondContact O-N 2.65Å; I414-R416 PolarHBondContact O-N 2.97Å; R416-V419 PolarHBondContact O-N 3.3Å; R416-N420 VanDerWaalsContact O-CB 3.29Å; R416-N420 WeakPolarHBondContact O-CB 3.46Å; R416-N420 PolarHBondContact O-N 3.02Å; R416-N420 PolarHBondContact O-OD1 2.97Å
417	A	96.3	Very high	96.1	Very high	12 Å²	12	64.1 Å²	64.1	10%	0.099	33%	0.325	C	S	.	.	H	α-helix	trans	-61	-44.8	176.7	0	0	0	0	0	111.4	D312 V313 H413 I414 N420 S421	D312-A417 HydrophobicContact CB-CB 4.42Å; V313-A417 HydrophobicContact CG2-CB 4.42Å; H413-A417 VanDerWaalsContact O-CB 3.32Å; H413-A417 WeakPolarHBondContact O-CB 3.45Å; H413-A417 PolarHBondContact O-N 3.19Å; I414-A417 PolarHBondContact O-N 2.84Å; A417-N420 PolarHBondContact O-N 3.5Å; A417-S421 WeakPolarHBondContact O-CB 3.34Å; A417-S421 PolarHBondContact O-N 3.28Å
418	F	96.7	Very high	96	Very high	61 Å²	61	66.7 Å²	66.7	27%	0.268	34%	0.337	S	S	.	.	H	α-helix	trans	-60.7	-52.2	176.4	178.9	-108.1	0	0	0	112.4	I242 V313 I414 L415 N420 S421 Q422	I242-F418 HydrophobicContact CD1-CE2 3.72Å; I242-F418 HydrophobicContact CD1-CZ 3.9Å; V313-F418 HydrophobicContact CG1-CB 3.96Å; V313-F418 HydrophobicContact CG1-CD2 4.24Å; V313-F418 HydrophobicContact CG2-CB 4Å; V313-F418 HydrophobicContact CG2-CD2 4.32Å; I414-F418 PolarHBondContact O-N 3.37Å; L415-F418 PolarHBondContact O-N 2.96Å; F418-N420 PolarHBondContact O-N 3.5Å; F418-S421 PolarHBondContact O-N 3.02Å; F418-S421 VanDerWaalsContact O-N 3.16Å; F418-Q422 HydrophobicContact CD1-CG 4.47Å; F418-Q422 HydrophobicContact CD2-CG 4.4Å; F418-Q422 HydrophobicContact CE1-CG 4.02Å; F418-Q422 HydrophobicContact CE2-CG 3.93Å; F418-Q422 HydrophobicContact CZ-CG 3.72Å; F418-Q422 WeakPolarHBondContact O-CG 3.5Å; F418-Q422 PolarHBondContact O-N 2.97Å
419	V	97.4	Very high	96	Very high	76 Å²	76	65.6 Å²	65.6	46%	0.461	33%	0.331	S	S	.	.	H	α-helix	trans	-59.7	-44.6	179.4	169.8	0	0	0	0	111.3	L415 R416 S421 Q422 I423	L415-V419 WeakPolarHBondContact O-CG2 3.34Å; L415-V419 PolarHBondContact O-N 3.09Å; R416-V419 PolarHBondContact O-N 3.3Å; V419-S421 VanDerWaalsContact C-N 3.34Å; V419-S421 PolarHBondContact O-N 3.4Å; V419-Q422 PolarHBondContact O-N 3.1Å; V419-I423 HydrophobicContact CG1-CD1 3.67Å; V419-I423 HydrophobicContact CG1-CG1 4.44Å; V419-I423 VanDerWaalsContact O-CG1 3.29Å; V419-I423 WeakPolarHBondContact O-CG1 3.15Å; V419-I423 PolarHBondContact O-N 2.94Å
420	N	96.3	Very high	96	Very high	92 Å²	92	65.3 Å²	65.3	49%	0.492	33%	0.331	S	S	.	.	H	α-helix	trans	-60.9	-42.3	176.2	-73	4.4	0	0	0	111.9	R416 A417 F418 I423 Q424	R416-N420 VanDerWaalsContact O-CB 3.29Å; R416-N420 WeakPolarHBondContact O-CB 3.46Å; R416-N420 PolarHBondContact O-N 3.02Å; R416-N420 PolarHBondContact O-OD1 2.97Å; A417-N420 PolarHBondContact O-N 3.5Å; F418-N420 PolarHBondContact O-N 3.5Å; N420-I423 PolarHBondContact O-N 3.07Å; N420-Q424 WeakPolarHBondContact O-CB 3.43Å; N420-Q424 PolarHBondContact O-N 2.86Å
421	S	94.9	Very high	96.1	Very high	9 Å²	9	71.2 Å²	71.2	6%	0.063	36%	0.356	C	S	.	.	H	α-helix	trans	-64.6	-42.8	179	-160.4	0	0	0	0	112.1	E309 A417 F418 V419 G425	E309-S421 WeakPolarHBondContact CG-OG 3.33Å; A417-S421 WeakPolarHBondContact O-CB 3.34Å; A417-S421 PolarHBondContact O-N 3.28Å; F418-S421 PolarHBondContact O-N 3.02Å; F418-S421 VanDerWaalsContact O-N 3.16Å; V419-S421 VanDerWaalsContact C-N 3.34Å; V419-S421 PolarHBondContact O-N 3.4Å; S421-G425 PolarHBondContact O-N 3.48Å
422	Q	95.9	Very high	96	Very high	38 Å²	38	69.8 Å²	69.8	18%	0.178	35%	0.347	C	S	.	.	H	α-helix	trans	-63.3	-46.8	174.9	-62.3	-52.4	-73.6	0	0	111.6	E309 F418 V419 Q424 H426	E309-Q422 VanDerWaalsContact CD-NE2 3.34Å; E309-Q422 PolarHBondContact OE1-NE2 3.3Å; F418-Q422 HydrophobicContact CD1-CG 4.47Å; F418-Q422 HydrophobicContact CD2-CG 4.4Å; F418-Q422 HydrophobicContact CE1-CG 4.02Å; F418-Q422 HydrophobicContact CE2-CG 3.93Å; F418-Q422 HydrophobicContact CZ-CG 3.72Å; F418-Q422 WeakPolarHBondContact O-CG 3.5Å; F418-Q422 PolarHBondContact O-N 2.97Å; V419-Q422 PolarHBondContact O-N 3.1Å; Q422-Q424 PolarHBondContact O-N 3.27Å; Q422-H426 WeakPolarHBondContact O-CB 3.07Å; Q422-H426 PolarHBondContact O-N 3.35Å; Q422-H426 PolarHBondContact O-ND1 3.49Å
423	I	96.7	Very high	96	Very high	104 Å²	104	71.4 Å²	71.4	53%	0.533	34%	0.342	S	S	.	.	H	α-helix	trans	-61.1	-46.3	-179.9	-70.3	169.3	0	0	0	110.9	V419 N420 K427	V419-I423 HydrophobicContact CG1-CD1 3.67Å; V419-I423 HydrophobicContact CG1-CG1 4.44Å; V419-I423 VanDerWaalsContact O-CG1 3.29Å; V419-I423 WeakPolarHBondContact O-CG1 3.15Å; V419-I423 PolarHBondContact O-N 2.94Å; N420-I423 PolarHBondContact O-N 3.07Å; I423-K427 WeakPolarHBondContact O-CB 3.3Å; I423-K427 PolarHBondContact O-N 3.41Å
424	Q	95.2	Very high	95.9	Very high	89 Å²	89	71.4 Å²	71.4	42%	0.416	35%	0.345	S	S	.	.	H	α-helix	trans	-68.9	-46.2	-178.5	-174.4	62.8	17.6	0	0	111.7	N420 Q422 H426 K427 E428	N420-Q424 WeakPolarHBondContact O-CB 3.43Å; N420-Q424 PolarHBondContact O-N 2.86Å; Q422-Q424 PolarHBondContact O-N 3.27Å; Q424-H426 PolarHBondContact O-N 3.05Å; Q424-K427 PolarHBondContact O-N 3.45Å; Q424-E428 PolarHBondContact NE2-OE1 3.25Å; Q424-E428 PolarHBondContact O-N 3.46Å
425	G	94	Very high	95.7	Very high	9 Å²	9	74.5 Å²	74.5	9%	0.093	36%	0.361	C	S	.	.	H	α-helix	trans	-58.7	-48.8	177.2	0	0	0	0	0	112.5	S421 K427 E428 M429	S421-G425 PolarHBondContact O-N 3.48Å; G425-K427 VanDerWaalsContact C-N 3.32Å; G425-K427 PolarHBondContact O-N 3.42Å; G425-E428 PolarHBondContact O-N 2.92Å; G425-M429 WeakPolarHBondContact O-CB 3.47Å; G425-M429 PolarHBondContact O-N 3.39Å
426	H	95.8	Very high	95.3	Very high	114 Å²	114	70.4 Å²	70.4	53%	0.528	34%	0.34	S	S	.	.	H	α-helix	trans	-62.8	-35.9	175.8	-66.2	170	0	0	0	112.9	Q422 Q424 S430	Q422-H426 WeakPolarHBondContact O-CB 3.07Å; Q422-H426 PolarHBondContact O-N 3.35Å; Q422-H426 PolarHBondContact O-ND1 3.49Å; Q424-H426 PolarHBondContact O-N 3.05Å; H426-S430 WeakPolarHBondContact O-CB 3.37Å; H426-S430 PolarHBondContact O-N 3.36Å
427	K	97.1	Very high	94.9	Very high	143 Å²	143	70.7 Å²	70.7	62%	0.622	34%	0.341	S	S	*	.	H	α-helix	trans	-67.3	-43.8	176.9	-178.2	-178.8	177.9	-176.2	0	112.2	I423 Q424 G425 K431	I423-K427 WeakPolarHBondContact O-CB 3.3Å; I423-K427 PolarHBondContact O-N 3.41Å; Q424-K427 PolarHBondContact O-N 3.45Å; G425-K427 VanDerWaalsContact C-N 3.32Å; G425-K427 PolarHBondContact O-N 3.42Å; K427-K431 PolarHBondContact O-N 2.86Å
428	E	95.1	Very high	94.4	Very high	61 Å²	61	73.9 Å²	73.9	29%	0.285	36%	0.361	S	S	.	.	H	α-helix	trans	-68.4	-44.9	177.4	-70.3	-170.8	-138.7	0	0	111.7	K301 Q424 G425 S430 K431 V432	K301-E428 HydrophobicContact CD-CB 4.48Å; K301-E428 WeakPolarHBondContact CD-OE2 3.47Å; K301-E428 WeakPolarHBondContact CE-OE2 3.29Å; K301-E428 IonicContact NZ-OE2 2.67Å; K301-E428 PolarHBondContact NZ-OE2 3.03Å; Q424-E428 PolarHBondContact NE2-OE1 3.25Å; Q424-E428 PolarHBondContact O-N 3.46Å; G425-E428 PolarHBondContact O-N 2.92Å; E428-S430 PolarHBondContact O-N 3.3Å; E428-K431 WeakPolarHBondContact O-CB 3.41Å; E428-K431 PolarHBondContact O-N 3.41Å; E428-V432 PolarHBondContact O-N 3.49Å
429	M	95.5	Very high	93.7	Very high	27 Å²	27	75 Å²	75	13%	0.133	37%	0.366	C	S	.	.	H	α-helix	trans	-57.7	-49	174.1	-172.3	59.9	60	0	0	111.4	L298 K301 A302 G425 K431 V432 W433	L298-M429 HydrophobicContact CD2-SD 3.49Å; L298-M429 WeakPolarHBondContact CD2-SD 3.36Å; K301-M429 HydrophobicContact CB-CE 4.16Å; A302-M429 HydrophobicContact CB-CE 3.97Å; G425-M429 WeakPolarHBondContact O-CB 3.47Å; G425-M429 PolarHBondContact O-N 3.39Å; M429-K431 VanDerWaalsContact C-N 3.3Å; M429-K431 PolarHBondContact O-N 3.28Å; M429-V432 PolarHBondContact O-N 2.74Å; M429-W433 PolarHBondContact O-N 2.67Å; M429-W433 VanDerWaalsContact O-N 3.08Å; M429-W433 PolarHBondContact SD-NE1 3.1Å; M429-W433 VanDerWaalsContact SD-NE1 3.4Å
430	S	97.1	Very high	92.7	Very high	60 Å²	60	74.4 Å²	74.4	42%	0.42	36%	0.359	S	S	.	.	H	α-helix	trans	-59.8	-37.3	176.9	-179.7	0	0	0	0	112.6	H426 E428 W433 N434	H426-S430 WeakPolarHBondContact O-CB 3.37Å; H426-S430 PolarHBondContact O-N 3.36Å; E428-S430 PolarHBondContact O-N 3.3Å; S430-W433 PolarHBondContact O-N 3.45Å; S430-N434 PolarHBondContact O-N 3.42Å; S430-N434 PolarHBondContact O-ND2 3.32Å; S430-N434 PolarHBondContact OG-ND2 3.23Å
431	K	96.1	Very high	91.4	Very high	134 Å²	134	73.6 Å²	73.6	58%	0.583	36%	0.361	S	S	*	.	H	α-helix	trans	-58.9	-52	174.9	-168	-159.2	170	-160.4	0	110.9	K427 E428 M429 W433 N434 D435	K427-K431 PolarHBondContact O-N 2.86Å; E428-K431 WeakPolarHBondContact O-CB 3.41Å; E428-K431 PolarHBondContact O-N 3.41Å; M429-K431 VanDerWaalsContact C-N 3.3Å; M429-K431 PolarHBondContact O-N 3.28Å; K431-W433 VanDerWaalsContact C-N 3.33Å; K431-W433 PolarHBondContact O-N 2.92Å; K431-N434 PolarHBondContact O-N 3.36Å; K431-N434 VanDerWaalsContact O-N 3.09Å; K431-D435 VanDerWaalsContact CE-OD2 3.24Å; K431-D435 WeakPolarHBondContact CE-OD2 3.1Å; K431-D435 IonicContact NZ-OD2 2.69Å; K431-D435 PolarHBondContact O-N 3.31Å
432	V	95.1	Very high	89.8	Confident	8 Å²	8	77.6 Å²	77.6	5%	0.048	39%	0.388	C	S	.	.	H	α-helix	trans	-64.3	-37.6	-177.4	-174	0	0	0	0	111.5	L297 L298 K301 E428 M429 N434 D435 L436	L297-V432 HydrophobicContact CB-CG1 4.42Å; L297-V432 HydrophobicContact CD2-CG1 3.99Å; L297-V432 HydrophobicContact CD2-CG2 3.97Å; L297-V432 HydrophobicContact CG-CG1 4.13Å; L297-V432 HydrophobicContact CG-CG2 4.01Å; L298-V432 HydrophobicContact CD2-CB 3.68Å; L298-V432 HydrophobicContact CD2-CG1 3.6Å; L298-V432 HydrophobicContact CG-CB 4.3Å; L298-V432 HydrophobicContact CG-CG1 3.66Å; K301-V432 HydrophobicContact CG-CG2 4.42Å; E428-V432 PolarHBondContact O-N 3.49Å; M429-V432 PolarHBondContact O-N 2.74Å; V432-N434 VanDerWaalsContact C-N 3.35Å; V432-N434 PolarHBondContact O-N 2.61Å; V432-D435 PolarHBondContact O-N 2.96Å; V432-L436 VanDerWaalsContact O-CB 3.3Å; V432-L436 WeakPolarHBondContact O-CB 3.21Å; V432-L436 PolarHBondContact O-N 3.41Å
433	W	95.1	Very high	88.3	Confident	108 Å²	108	77.8 Å²	77.8	41%	0.409	39%	0.39	S	S	.	.	H	α-helix	trans	-63.5	-36.4	172.7	-71.1	118	0	0	0	113.5	L253 F295 L298 M429 S430 K431 L436 R437	L253-W433 HydrophobicContact CD2-CH2 4.41Å; L253-W433 HydrophobicContact CD2-CZ2 4.27Å; F295-W433 HydrophobicContact CE1-CH2 4.09Å; F295-W433 HydrophobicContact CZ-CH2 4.16Å; F295-W433 HydrophobicContact CZ-CZ3 4.24Å; L298-W433 HydrophobicContact CD1-CD2 4.24Å; L298-W433 HydrophobicContact CD1-CE3 4.06Å; L298-W433 HydrophobicContact CD1-CH2 3.48Å; L298-W433 VanDerWaalsContact CD1-CH2 3.48Å; L298-W433 HydrophobicContact CD1-CZ2 3.67Å; L298-W433 HydrophobicContact CD1-CZ3 3.68Å; L298-W433 HydrophobicContact CD2-CD2 3.92Å; L298-W433 HydrophobicContact CD2-CG 4.22Å; L298-W433 HydrophobicContact CD2-CZ2 3.94Å; L298-W433 HydrophobicContact CG-CZ2 4.4Å; M429-W433 PolarHBondContact O-N 2.67Å; M429-W433 VanDerWaalsContact O-N 3.08Å; M429-W433 PolarHBondContact SD-NE1 3.1Å; M429-W433 VanDerWaalsContact SD-NE1 3.4Å; S430-W433 PolarHBondContact O-N 3.45Å; K431-W433 VanDerWaalsContact C-N 3.33Å; K431-W433 PolarHBondContact O-N 2.92Å; W433-L436 HydrophobicContact CE3-CD2 3.71Å; W433-L436 HydrophobicContact CZ3-CD2 3.63Å; W433-L436 PolarHBondContact O-N 2.89Å; W433-R437 PolarHBondContact O-N 3.37Å
434	N	94.2	Very high	86.5	Confident	88 Å²	88	80.1 Å²	80.1	47%	0.471	40%	0.397	S	S	.	.	H	α-helix	trans	-72.5	-37.7	174.7	-76.9	-68.8	0	0	0	112.2	S430 K431 V432 L436 R437 P438	S430-N434 PolarHBondContact O-N 3.42Å; S430-N434 PolarHBondContact O-ND2 3.32Å; S430-N434 PolarHBondContact OG-ND2 3.23Å; K431-N434 PolarHBondContact O-N 3.36Å; K431-N434 VanDerWaalsContact O-N 3.09Å; V432-N434 VanDerWaalsContact C-N 3.35Å; V432-N434 PolarHBondContact O-N 2.61Å; N434-L436 VanDerWaalsContact C-N 3.28Å; N434-L436 PolarHBondContact O-N 2.89Å; N434-R437 PolarHBondContact O-N 3.19Å; N434-P438 WeakPolarHBondContact O-CD 3.4Å
435	D	90.9	Very high	84.6	Confident	68 Å²	68	79.5 Å²	79.5	36%	0.364	41%	0.406	S	S	.	.	H	α-helix	trans	-66.3	-30	173.4	-66.8	-22.1	0	0	0	111.5	K431 V432 K439	K431-D435 VanDerWaalsContact CE-OD2 3.24Å; K431-D435 WeakPolarHBondContact CE-OD2 3.1Å; K431-D435 IonicContact NZ-OD2 2.69Å; K431-D435 PolarHBondContact O-N 3.31Å; V432-D435 PolarHBondContact O-N 2.96Å; D435-K439 WeakPolarHBondContact O-CE 3.3Å
436	L	89.7	Confident	82.5	Confident	5 Å²	5	80.1 Å²	80.1	3%	0.026	41%	0.413	C	S	.	.	H	α-helix	trans	-74.7	-41.3	175	-175	62.5	0	0	0	113.1	L291 E294 F295 L298 V432 W433 N434 K439 L440	L291-L436 HydrophobicContact CD2-CD1 3.47Å; L291-L436 VanDerWaalsContact CD2-CD1 3.47Å; E294-L436 HydrophobicContact CB-CD1 3.63Å; E294-L436 HydrophobicContact CG-CD1 3.68Å; F295-L436 HydrophobicContact CE2-CD2 4.21Å; L298-L436 HydrophobicContact CD1-CD2 4.43Å; V432-L436 VanDerWaalsContact O-CB 3.3Å; V432-L436 WeakPolarHBondContact O-CB 3.21Å; V432-L436 PolarHBondContact O-N 3.41Å; W433-L436 HydrophobicContact CE3-CD2 3.71Å; W433-L436 HydrophobicContact CZ3-CD2 3.63Å; W433-L436 PolarHBondContact O-N 2.89Å; N434-L436 VanDerWaalsContact C-N 3.28Å; N434-L436 PolarHBondContact O-N 2.89Å; L436-K439 WeakPolarHBondContact O-CA 3.23Å; L436-K439 VanDerWaalsContact O-CB 3.3Å; L436-K439 WeakPolarHBondContact O-CB 3.28Å; L436-K439 PolarHBondContact O-N 3.48Å; L436-L440 PolarHBondContact O-N 3.25Å
437	R	87.4	Confident	80.2	Confident	179 Å²	179	79.9 Å²	79.9	68%	0.675	42%	0.421	S	S	*	.	H	α-helix	trans	-48.2	-48.3	-173.3	-173.5	177.5	179.1	-177.3	0.4	115	W433 N434 K439 L440	W433-R437 PolarHBondContact O-N 3.37Å; N434-R437 PolarHBondContact O-N 3.19Å; R437-K439 VanDerWaalsContact C-N 3.29Å; R437-K439 PolarHBondContact O-N 2.94Å; R437-L440 WeakPolarHBondContact O-CB 3.42Å; R437-L440 PolarHBondContact O-N 3.03Å
438	P	85.4	Confident	77.6	Confident	79 Å²	79	81.8 Å²	81.8	51%	0.513	43%	0.432	S	S	.	.	H	α-helix	trans	-70.9	-22.9	178.9	28.8	-35.7	0	0	0	113.3	N434 L440 S441	N434-P438 WeakPolarHBondContact O-CD 3.4Å; P438-L440 VanDerWaalsContact C-N 3.28Å; P438-L440 PolarHBondContact O-N 3.19Å; P438-S441 VanDerWaalsContact O-CB 3.29Å; P438-S441 WeakPolarHBondContact O-CB 3.13Å; P438-S441 PolarHBondContact O-N 3.45Å; P438-S441 PolarHBondContact O-OG 3.31Å
439	K	81.9	Confident	75.1	Confident	84 Å²	84	82.2 Å²	82.2	37%	0.365	44%	0.442	S	S	.	.	H	α-helix	trans	-70.4	-28.1	177.2	-55.3	172.9	-174.9	169.3	0	111.1	L291 E294 D435 L436 R437 S441 C442	L291-K439 HydrophobicContact CD2-CB 4.31Å; E294-K439 HydrophobicContact CG-CD 4.29Å; E294-K439 IonicContact OE1-NZ 3.53Å; E294-K439 PolarHBondContact OE1-NZ 3.41Å; E294-K439 IonicContact OE2-NZ 2.96Å; E294-K439 PolarHBondContact OE2-NZ 3.17Å; D435-K439 WeakPolarHBondContact O-CE 3.3Å; L436-K439 WeakPolarHBondContact O-CA 3.23Å; L436-K439 VanDerWaalsContact O-CB 3.3Å; L436-K439 WeakPolarHBondContact O-CB 3.28Å; L436-K439 PolarHBondContact O-N 3.48Å; R437-K439 VanDerWaalsContact C-N 3.29Å; R437-K439 PolarHBondContact O-N 2.94Å; K439-S441 VanDerWaalsContact C-N 3.31Å; K439-S441 PolarHBondContact O-N 2.93Å; K439-C442 PolarHBondContact O-N 3.32Å
440	L	78.2	Confident	72.3	Confident	63 Å²	63	85.2 Å²	85.2	33%	0.33	47%	0.471	S	S	.	.	H	α-helix	trans	-66.7	-29.9	173	-57.7	177.2	0	0	0	112.6	L291 L436 R437 P438 C442 L443 F444	L291-L440 HydrophobicContact CD1-CD2 4Å; L291-L440 HydrophobicContact CD2-CD2 3.83Å; L436-L440 PolarHBondContact O-N 3.25Å; R437-L440 WeakPolarHBondContact O-CB 3.42Å; R437-L440 PolarHBondContact O-N 3.03Å; P438-L440 VanDerWaalsContact C-N 3.28Å; P438-L440 PolarHBondContact O-N 3.19Å; L440-C442 PolarHBondContact O-N 3.05Å; L440-L443 HydrophobicContact CB-CD1 4.16Å; L440-L443 HydrophobicContact CD2-CD1 3.68Å; L440-L443 VanDerWaalsContact O-CB 3.23Å; L440-L443 WeakPolarHBondContact O-CB 3.49Å; L440-L443 WeakPolarHBondContact O-CG 3.42Å; L440-L443 PolarHBondContact O-N 2.86Å; L440-F444 VanDerWaalsContact O-CD2 3.28Å; L440-F444 WeakPolarHBondContact O-CD2 3.46Å
441	S	68.6	Low	69.5	Low	76 Å²	76	90.5 Å²	90.5	53%	0.531	49%	0.494	S	S	.	.	H	α-helix	trans	-57	-33.8	177.2	-52.8	0	0	0	0	112.2	P438 K439 L443 F444 A445	P438-S441 VanDerWaalsContact O-CB 3.29Å; P438-S441 WeakPolarHBondContact O-CB 3.13Å; P438-S441 PolarHBondContact O-N 3.45Å; P438-S441 PolarHBondContact O-OG 3.31Å; K439-S441 VanDerWaalsContact C-N 3.31Å; K439-S441 PolarHBondContact O-N 2.93Å; S441-L443 PolarHBondContact O-N 2.9Å; S441-F444 PolarHBondContact O-N 3.31Å; S441-A445 PolarHBondContact O-N 3.15Å
442	C	61.8	Low	66.5	Low	93 Å²	93	90.2 Å²	90.2	63%	0.628	50%	0.504	S	S	*	.	H	α-helix	trans	-68.5	-16.9	177.4	-58.2	0	0	0	0	113.8	K439 L440	K439-C442 PolarHBondContact O-N 3.32Å; L440-C442 PolarHBondContact O-N 3.05Å
443	L	63.8	Low	63.7	Low	41 Å²	41	94.8 Å²	94.8	22%	0.215	53%	0.533	C	S	.	.	H	α-helix	trans	-73.2	-33.2	173.5	-57.3	165.9	0	0	0	112	L284 A287 L291 L440 S441	L284-L443 HydrophobicContact CD1-CB 4.44Å; L284-L443 HydrophobicContact CD1-CD2 3.53Å; A287-L443 HydrophobicContact CB-CD2 3.46Å; A287-L443 VanDerWaalsContact CB-CD2 3.46Å; L291-L443 HydrophobicContact CD1-CD1 4.07Å; L291-L443 HydrophobicContact CD1-CD2 4.1Å; L440-L443 HydrophobicContact CB-CD1 4.16Å; L440-L443 HydrophobicContact CD2-CD1 3.68Å; L440-L443 VanDerWaalsContact O-CB 3.23Å; L440-L443 WeakPolarHBondContact O-CB 3.49Å; L440-L443 WeakPolarHBondContact O-CG 3.42Å; L440-L443 PolarHBondContact O-N 2.86Å; S441-L443 PolarHBondContact O-N 2.9Å
444	F	59.4	Low	61.1	Low	154 Å²	154	95.6 Å²	95.6	68%	0.675	55%	0.552	S	S	*	*	H	α-helix	trans	-103.4	-2.2	-169.7	-58	-72.1	0	0	0	113.3	L440 S441 G446 S449	L440-F444 VanDerWaalsContact O-CD2 3.28Å; L440-F444 WeakPolarHBondContact O-CD2 3.46Å; S441-F444 PolarHBondContact O-N 3.31Å; F444-G446 PolarHBondContact O-N 3.07Å; F444-S449 WeakPolarHBondContact O-CB 3.14Å; F444-S449 PolarHBondContact O-OG 2.71Å
445	A	54	Low	58.3	Low	75 Å²	75	97.5 Å²	97.5	62%	0.62	57%	0.571	S	S	*	*			trans	-77	62.7	175.3	0	0	0	0	0	112.1	S441	S441-A445 PolarHBondContact O-N 3.15Å
446	G	51.2	Low	56	Low	22 Å²	22	99.1 Å²	99.1	23%	0.227	59%	0.588	C	S	.	*			trans	-72.3	166.4	166.6	0	0	0	0	0	112	F444 H448 S449	F444-G446 PolarHBondContact O-N 3.07Å; G446-H448 PolarHBondContact O-N 3.41Å; G446-S449 PolarHBondContact N-OG 3.15Å; G446-S449 PolarHBondContact O-N 2.85Å; G446-S449 VanDerWaalsContact O-N 3.07Å
447	P	45.8	Very low	53.6	Low	109 Å²	109	104.2 Å²	104.2	71%	0.708	62%	0.621	S	S	*	*	T	Hydrogen-bonded Turn	trans	-60.2	-7.5	-172.5	-26.7	36.1	0	0	0	117.2
448	H	44.3	Very low	51.3	Low	183 Å²	183	101.2 Å²	101.2	85%	0.847	63%	0.625	S	S	*	*	T	Hydrogen-bonded Turn	trans	-125.7	11	-179.6	-62	-43.8	0	0	0	113.8	G446 A450	G446-H448 PolarHBondContact O-N 3.41Å; H448-A450 PolarHBondContact O-N 3.35Å
449	S	42.5	Very low	49.1	Very low	70 Å²	70	106.8 Å²	106.8	49%	0.49	64%	0.644	S	S	.	*			trans	-76.8	62.6	178.5	-61.6	0	0	0	0	112.4	F444 G446 L451	F444-S449 WeakPolarHBondContact O-CB 3.14Å; F444-S449 PolarHBondContact O-OG 2.71Å; G446-S449 PolarHBondContact N-OG 3.15Å; G446-S449 PolarHBondContact O-N 2.85Å; G446-S449 VanDerWaalsContact O-N 3.07Å; S449-L451 PolarHBondContact O-N 3.16Å; S449-L451 VanDerWaalsContact O-N 3.15Å
450	A	35.7	Very low	47.1	Very low	91 Å²	91	110.7 Å²	110.7	75%	0.752	67%	0.669	S	S	*	*			trans	-67.7	106.7	168.3	0	0	0	0	0	109.2	H448 T452	H448-A450 PolarHBondContact O-N 3.35Å; A450-T452 PolarHBondContact O-N 3.47Å
451	L	38.9	Very low	45.1	Very low	170 Å²	170	111.1 Å²	111.1	89%	0.89	69%	0.689	S	S	*	*			trans	-67.6	102.4	177.1	-73.4	165.3	0	0	0	110	S449	S449-L451 PolarHBondContact O-N 3.16Å; S449-L451 VanDerWaalsContact O-N 3.15Å
452	T	33.1	Very low	44	Very low	129 Å²	129	116 Å²	116	79%	0.791	71%	0.708	S	S	*	*	P	Polyproline II helix	trans	-61	132.4	159.3	23.4	0	0	0	0	108.9	A450	A450-T452 PolarHBondContact O-N 3.47Å
453	P	36.7	Very low	42.7	Very low	104 Å²	104	117.4 Å²	117.4	68%	0.675	72%	0.717	S	S	*	*	P	Polyproline II helix	trans	-64.5	151.1	173.2	28.9	-34.4	0	0	0	109.7	C455	P453-C455 PolarHBondContact O-N 3.28Å
454	P	38.8	Very low	42.1	Very low	124 Å²	124	120.2 Å²	120.2	81%	0.805	74%	0.738	S	S	*	*	P	Polyproline II helix	trans	-61.8	129.1	171.8	27.6	-33.5	0	0	0	108.9	S456	P454-S456 PolarHBondContact O-N 3.4Å
455	C	35.8	Very low	41.2	Very low	128 Å²	128	125.1 Å²	125.1	87%	0.865	76%	0.763	S	S	*	*	P	Polyproline II helix	trans	-57.9	128.7	172.9	-63.6	0	0	0	0	109.5	P453	P453-C455 PolarHBondContact O-N 3.28Å
456	S	43.4	Very low	40.6	Very low	103 Å²	103	127.7 Å²	127.7	72%	0.72	77%	0.77	S	S	*	*	P	Polyproline II helix	trans	-52.5	146.9	163.1	-52.9	0	0	0	0	109.6	P454	P454-S456 PolarHBondContact O-N 3.4Å
457	P	39.3	Very low	40	Very low	111 Å²	111	133.2 Å²	133.2	72%	0.721	80%	0.799	S	S	*	*	P	Polyproline II helix	trans	-57.4	146.9	163.4	28.6	-34.4	0	0	0	108.8
458	P	38.6	Very low	39.7	Very low	117 Å²	117	134.6 Å²	134.6	76%	0.76	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-60.3	141.1	171.3	28.1	-34.1	0	0	0	109.3	D460	P458-D460 PolarHBondContact O-N 3.28Å
459	E	39.7	Very low	39.4	Very low	195 Å²	195	131.7 Å²	131.7	91%	0.911	80%	0.801	S	S	*	*	P	Polyproline II helix	trans	-66.5	126.8	167.6	-64.4	-176.6	126.2	0	0	108.4	G461	E459-G461 PolarHBondContact O-N 3.22Å
460	D	39.7	Very low	39.2	Very low	166 Å²	166	135.6 Å²	135.6	89%	0.888	82%	0.821	S	S	*	*			trans	-65.3	100	172.5	-88.5	-44.8	0	0	0	109	P458 L462	P458-D460 PolarHBondContact O-N 3.28Å; D460-L462 PolarHBondContact O-N 2.92Å
461	G	35.9	Very low	39.5	Very low	72 Å²	72	138.5 Å²	138.5	74%	0.742	83%	0.825	S	S	*	*			trans	-62.1	118.2	178.5	0	0	0	0	0	111.3	E459 C463	E459-G461 PolarHBondContact O-N 3.22Å; G461-C463 PolarHBondContact O-N 3.43Å
462	L	44.8	Very low	39.5	Very low	178 Å²	178	136.3 Å²	136.3	93%	0.932	82%	0.821	S	S	*	*			trans	-45.7	132.9	168.2	-77.9	148.4	0	0	0	111.6	D460	D460-L462 PolarHBondContact O-N 2.92Å
463	C	35.4	Very low	40	Very low	123 Å²	123	136.8 Å²	136.8	83%	0.831	82%	0.823	S	S	*	*			trans	-140.8	137.6	155.1	-132.4	0	0	0	0	109.3	G461	G461-C463 PolarHBondContact O-N 3.43Å
464	P	51.3	Low	40.3	Very low	101 Å²	101	139.6 Å²	139.6	66%	0.656	84%	0.835	S	S	*	*			trans	-93.3	145.7	-168.8	35.6	-34.4	0	0	0	113.1
465	H	40.5	Very low	40.4	Very low	257 Å²	257	141 Å²	141	100%	1.19	84%	0.838	S	S	*	*				-174.7	0	108.4	-101.1	-64.1	0	0	0	112.9

Retrieved 465 of 465 residues in 238.9 ms (Link to these results)

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