A0A096NSS3_PAPAN Loading...

Otopetrin 2

AlphaFold DB , UniProt , Accession A0A096NSS3, Species PAPAN (Papio anubis, Olive baboon), Gene OTOP2, Length 562 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37.4	Very low	37.7	Very low	230 Å²	230	154.5 Å²	154.5	100%	1.133	87%	0.865	S	S	*	*				0	87.6	0	-154.1	168.1	85.3	0	0	105.7
2	S	33.9	Very low	38	Very low	126 Å²	126	150.4 Å²	150.4	88%	0.881	86%	0.855	S	S	*	*			trans	-106.6	107.7	-179.4	-65.7	0	0	0	0	105.9	E4	S2-E4 PolarHBondContact O-N 3.25Å
3	E	36.2	Very low	38.4	Very low	183 Å²	183	147.7 Å²	147.7	86%	0.855	85%	0.847	S	S	*	*			trans	-69.1	124.4	178.1	-108.2	167.5	101.2	0	0	110
4	E	35.3	Very low	38.5	Very low	196 Å²	196	146.1 Å²	146.1	92%	0.916	85%	0.845	S	S	*	*			trans	-78.3	114.3	174.3	-157.1	179	132.1	0	0	108	S2	S2-E4 PolarHBondContact O-N 3.25Å
5	L	36.8	Very low	38.8	Very low	171 Å²	171	142.1 Å²	142.1	90%	0.895	84%	0.835	S	S	*	*	P	Polyproline II helix	trans	-86	117.4	179.9	-156.5	81.6	0	0	0	109.7
6	A	40.5	Very low	38.9	Very low	85 Å²	85	141.2 Å²	141.2	70%	0.702	84%	0.835	S	S	*	*	P	Polyproline II helix	trans	-61	147.9	179.7	0	0	0	0	0	113.3	G8	A6-G8 PolarHBondContact O-N 3.48Å
7	P	39.3	Very low	38.8	Very low	130 Å²	130	147.3 Å²	147.3	84%	0.844	84%	0.84	S	S	*	*	P	Polyproline II helix	trans	-77.1	123.4	174.1	30.3	-29.7	0	0	0	110.4
8	G	40.4	Very low	39	Very low	63 Å²	63	145 Å²	145	65%	0.649	84%	0.842	S	S	*	*	P	Polyproline II helix	trans	-67.1	165.7	172.8	0	0	0	0	0	113.2	A6 Q10	A6-G8 PolarHBondContact O-N 3.48Å; G8-Q10 PolarHBondContact O-N 3.1Å
9	P	38	Very low	39	Very low	130 Å²	130	139.9 Å²	139.9	84%	0.844	82%	0.824	S	S	*	*	P	Polyproline II helix	trans	-67.2	132.3	-173.1	-2.4	16.7	0	0	0	110.7	E11	P9-E11 PolarHBondContact O-N 3.4Å; P9-E11 VanDerWaalsContact O-N 3.13Å
10	Q	38.9	Very low	39.2	Very low	193 Å²	193	139.5 Å²	139.5	90%	0.902	83%	0.825	S	S	*	*			trans	-58.9	114.2	169.3	-85.1	-171.7	-7.3	0	0	109.8	G8 S12	G8-Q10 PolarHBondContact O-N 3.1Å; Q10-S12 PolarHBondContact O-N 2.04Å
11	E	37.6	Very low	39.4	Very low	192 Å²	192	142.3 Å²	142.3	90%	0.897	82%	0.822	S	S	*	*	P	Polyproline II helix	trans	-63.9	118.5	163	-79.1	-174.5	141.5	0	0	109.2	P9	P9-E11 PolarHBondContact O-N 3.4Å; P9-E11 VanDerWaalsContact O-N 3.13Å
12	S	42	Very low	39.8	Very low	106 Å²	106	138.6 Å²	138.6	74%	0.741	80%	0.802	S	S	*	*	P	Polyproline II helix	trans	-54	137.2	170.9	-39.4	0	0	0	0	110.4	Q10	Q10-S12 PolarHBondContact O-N 2.04Å
13	P	42.4	Very low	40.1	Very low	115 Å²	115	138.6 Å²	138.6	75%	0.747	80%	0.796	S	S	*	*	P	Polyproline II helix	trans	-61.5	143.1	173.9	25.7	-31.9	0	0	0	109.7	A15	P13-A15 PolarHBondContact O-N 3.02Å
14	P	40.5	Very low	40.4	Very low	126 Å²	126	139.6 Å²	139.6	82%	0.818	79%	0.792	S	S	*	*	P	Polyproline II helix	trans	-62.2	134.2	-177.3	24.7	-31.9	0	0	0	109.9
15	A	42.8	Very low	41.2	Very low	85 Å²	85	134.8 Å²	134.8	70%	0.702	77%	0.768	S	S	*	*	P	Polyproline II helix	trans	-51.5	139.7	174	0	0	0	0	0	110.3	P13 R17	P13-A15 PolarHBondContact O-N 3.02Å; A15-R17 PolarHBondContact O-N 3.42Å
16	P	39.7	Very low	42.4	Very low	128 Å²	128	133.9 Å²	133.9	83%	0.831	76%	0.757	S	S	*	*	P	Polyproline II helix	trans	-61.5	117.2	-179.5	23.6	-30.6	0	0	0	109	A18	P16-A18 PolarHBondContact O-N 3.22Å
17	R	37.8	Very low	44	Very low	245 Å²	245	131.8 Å²	131.8	93%	0.925	74%	0.744	S	S	*	*	P	Polyproline II helix	trans	-51.8	117.1	171.5	-78.6	-179.5	174.8	173.4	-1.5	108.6	A15 G19	A15-R17 PolarHBondContact O-N 3.42Å; R17-G19 VanDerWaalsContact C-N 3.32Å; R17-G19 PolarHBondContact O-N 3.13Å
18	A	43.3	Very low	46	Very low	106 Å²	106	125.8 Å²	125.8	88%	0.876	71%	0.706	S	S	*	*			trans	-64.8	94.1	168.7	0	0	0	0	0	108.5	P16	P16-A18 PolarHBondContact O-N 3.22Å
19	G	38.8	Very low	48.1	Very low	48 Å²	48	128.1 Å²	128.1	50%	0.495	70%	0.695	S	S	.	*			trans	-68.8	150.7	171.5	0	0	0	0	0	111	R17 R21	R17-G19 VanDerWaalsContact C-N 3.32Å; R17-G19 PolarHBondContact O-N 3.13Å; G19-R21 VanDerWaalsContact C-N 3.27Å; G19-R21 PolarHBondContact O-N 2.92Å
20	P	41.8	Very low	50.6	Low	131 Å²	131	127 Å²	127	85%	0.851	68%	0.682	S	S	*	*	S	Bend	trans	-74.1	79.9	175.1	31.4	-32.1	0	0	0	109.3
21	R	43.3	Very low	53	Low	200 Å²	200	122.7 Å²	122.7	76%	0.755	66%	0.664	S	S	*	*			trans	-106.8	-6.4	-167	-119.3	177.4	178.9	-178.8	0.5	115.8	G19	G19-R21 VanDerWaalsContact C-N 3.27Å; G19-R21 PolarHBondContact O-N 2.92Å
22	E	46.8	Very low	55.7	Low	151 Å²	151	113.6 Å²	113.6	71%	0.706	62%	0.621	S	S	*	*	S	Bend	trans	-91.5	-32.6	-176.5	-68.2	-162.6	154.4	0	0	114.6
23	V	41	Very low	58.1	Low	126 Å²	126	111.5 Å²	111.5	76%	0.764	60%	0.604	S	S	*	*	H	α-helix	trans	-70.3	-42.4	-174.7	-177.7	0	0	0	0	111.5	K25 K26	V23-K25 PolarHBondContact O-N 3.1Å; V23-K26 PolarHBondContact O-N 3.38Å
24	W	41.8	Very low	60.5	Low	205 Å²	205	110.3 Å²	110.3	78%	0.777	59%	0.591	S	S	*	*	H	α-helix	trans	-73.3	-27.7	-178.4	-134.9	72.7	0	0	0	113.5	K26 G27	W24-K26 VanDerWaalsContact C-N 3.27Å; W24-K26 PolarHBondContact O-N 3.36Å; W24-G27 PolarHBondContact O-N 3.16Å
25	K	52.1	Low	63	Low	95 Å²	95	107.6 Å²	107.6	41%	0.413	57%	0.569	S	S	.	*	H	α-helix	trans	-64.8	-29.1	173.9	-92	-174	175.9	-172.9	0	112.8	V23	V23-K25 PolarHBondContact O-N 3.1Å
26	K	60.8	Low	65.4	Low	151 Å²	151	104.1 Å²	104.1	66%	0.657	54%	0.541	S	S	*	.	H	α-helix	trans	-77.4	-34.8	-180	-69.3	178.7	-178.1	175.4	0	112.5	V23 W24 R29 L30	V23-K26 PolarHBondContact O-N 3.38Å; W24-K26 VanDerWaalsContact C-N 3.27Å; W24-K26 PolarHBondContact O-N 3.36Å; K26-R29 PolarHBondContact O-N 3.37Å; K26-L30 PolarHBondContact O-N 3.3Å
27	G	75.2	Confident	67.9	Low	41 Å²	41	100 Å²	100	42%	0.423	52%	0.518	S	S	.	.	H	α-helix	trans	-60.5	-48.1	-177.6	0	0	0	0	0	114.2	W24 R29 L30 L31	W24-G27 PolarHBondContact O-N 3.16Å; G27-R29 VanDerWaalsContact C-N 3.3Å; G27-R29 PolarHBondContact O-N 3.01Å; G27-L30 PolarHBondContact O-N 2.82Å; G27-L31 WeakPolarHBondContact O-CB 3.05Å; G27-L31 PolarHBondContact O-N 3.48Å
28	G	80.7	Confident	70.7	Confident	5 Å²	5	93.5 Å²	93.5	5%	0.052	50%	0.501	C	S	.	.	H	α-helix	trans	-66.4	-28.8	178.5	0	0	0	0	0	114.3	S32 N167	G28-S32 PolarHBondContact O-N 3.18Å; G28-S32 PolarHBondContact O-OG 2.88Å; G28-N167 WeakPolarHBondContact CA-OD1 3.35Å
29	R	85.7	Confident	73.1	Confident	112 Å²	112	89.9 Å²	89.9	42%	0.423	47%	0.468	S	S	.	.	H	α-helix	trans	-71.3	-47.7	174.7	-169.2	179.1	-82.2	176.1	-4.4	110.4	K26 G27 S32 V33 W262	K26-R29 PolarHBondContact O-N 3.37Å; G27-R29 VanDerWaalsContact C-N 3.3Å; G27-R29 PolarHBondContact O-N 3.01Å; R29-S32 PolarHBondContact O-N 3.35Å; R29-S32 PolarHBondContact O-OG 3.04Å; R29-V33 WeakPolarHBondContact O-CG2 3.37Å; R29-V33 PolarHBondContact O-N 2.82Å; R29-W262 HydrophobicContact CB-CZ2 4.48Å; R29-W262 HydrophobicContact CG-CH2 3.52Å; R29-W262 HydrophobicContact CG-CZ2 3.26Å
30	L	88.7	Confident	75.7	Confident	107 Å²	107	89.9 Å²	89.9	56%	0.56	46%	0.456	S	S	*	.	H	α-helix	trans	-59.7	-46.5	176.9	-178.6	63.8	0	0	0	111.5	K26 G27 S32 V33 L34	K26-L30 PolarHBondContact O-N 3.3Å; G27-L30 PolarHBondContact O-N 2.82Å; L30-S32 VanDerWaalsContact C-N 3.34Å; L30-S32 PolarHBondContact O-N 2.77Å; L30-V33 PolarHBondContact O-N 3.24Å; L30-V33 VanDerWaalsContact O-N 3.15Å; L30-L34 HydrophobicContact CD1-CD1 4.26Å; L30-L34 HydrophobicContact CD1-CG 4.26Å; L30-L34 HydrophobicContact CG-CD1 3.95Å; L30-L34 HydrophobicContact CG-CG 4.37Å; L30-L34 WeakPolarHBondContact O-CG 3.13Å; L30-L34 PolarHBondContact O-N 3.28Å
31	L	91	Very high	78.2	Confident	102 Å²	102	89 Å²	89	53%	0.534	44%	0.443	S	S	.	.	H	α-helix	trans	-56.6	-46.5	177.6	-179.3	65.9	0	0	0	111.9	G27 V33 L34 L35	G27-L31 WeakPolarHBondContact O-CB 3.05Å; G27-L31 PolarHBondContact O-N 3.48Å; L31-V33 VanDerWaalsContact C-N 3.3Å; L31-V33 PolarHBondContact O-N 2.89Å; L31-L34 PolarHBondContact O-N 3.01Å; L31-L35 WeakPolarHBondContact O-CB 3.38Å; L31-L35 PolarHBondContact O-N 2.88Å
32	S	93.4	Very high	80.5	Confident	0 Å²	0	83.9 Å²	83.9	0%	0	43%	0.431	C	S	.	.	H	α-helix	trans	-62.6	-36.2	179.1	65.9	0	0	0	0	112.9	G28 R29 L30 A36 W262	G28-S32 PolarHBondContact O-N 3.18Å; G28-S32 PolarHBondContact O-OG 2.88Å; R29-S32 PolarHBondContact O-N 3.35Å; R29-S32 PolarHBondContact O-OG 3.04Å; L30-S32 VanDerWaalsContact C-N 3.34Å; L30-S32 PolarHBondContact O-N 2.77Å; S32-A36 WeakPolarHBondContact O-CB 3.39Å; S32-A36 PolarHBondContact O-N 3.47Å; S32-W262 PolarHBondContact OG-NE1 3.45Å
33	V	92.5	Very high	82.8	Confident	63 Å²	63	76.7 Å²	76.7	38%	0.382	40%	0.397	S	S	.	.	H	α-helix	trans	-72.4	-41.9	177.6	173.6	0	0	0	0	111	R29 L30 L31 A36 A37 W262	R29-V33 WeakPolarHBondContact O-CG2 3.37Å; R29-V33 PolarHBondContact O-N 2.82Å; L30-V33 PolarHBondContact O-N 3.24Å; L30-V33 VanDerWaalsContact O-N 3.15Å; L31-V33 VanDerWaalsContact C-N 3.3Å; L31-V33 PolarHBondContact O-N 2.89Å; V33-A36 WeakPolarHBondContact O-CB 3.13Å; V33-A36 PolarHBondContact O-N 3.49Å; V33-A37 WeakPolarHBondContact O-CB 3.27Å; V33-A37 PolarHBondContact O-N 3.01Å; V33-W262 HydrophobicContact CG2-CH2 3.94Å; V33-W262 HydrophobicContact CG2-CZ2 3.66Å
34	L	92.4	Very high	85.1	Confident	89 Å²	89	72.4 Å²	72.4	47%	0.466	37%	0.373	S	S	.	.	H	α-helix	trans	-63.6	-42.1	176.9	-71.4	173.2	0	0	0	111.6	L30 L31 A37 N38	L30-L34 HydrophobicContact CD1-CD1 4.26Å; L30-L34 HydrophobicContact CD1-CG 4.26Å; L30-L34 HydrophobicContact CG-CD1 3.95Å; L30-L34 HydrophobicContact CG-CG 4.37Å; L30-L34 WeakPolarHBondContact O-CG 3.13Å; L30-L34 PolarHBondContact O-N 3.28Å; L31-L34 PolarHBondContact O-N 3.01Å; L34-A37 PolarHBondContact O-N 3.41Å; L34-N38 PolarHBondContact O-N 2.99Å; L34-N38 PolarHBondContact O-ND2 3.43Å
35	L	93.4	Very high	87.4	Confident	70 Å²	70	66.8 Å²	66.8	37%	0.366	36%	0.361	S	S	.	.	H	α-helix	trans	-58.3	-50.6	172.4	178	67.2	0	0	0	110.7	L31 A37 N38 V39 C171	L31-L35 WeakPolarHBondContact O-CB 3.38Å; L31-L35 PolarHBondContact O-N 2.88Å; L35-A37 VanDerWaalsContact C-N 3.32Å; L35-A37 PolarHBondContact O-N 2.04Å; L35-N38 PolarHBondContact O-N 3.17Å; L35-V39 HydrophobicContact CD1-CG2 4.17Å; L35-V39 VanDerWaalsContact O-CG2 3.3Å; L35-V39 WeakPolarHBondContact O-CG2 3.4Å; L35-V39 PolarHBondContact O-N 3Å; L35-C171 HydrophobicContact CD2-CB 4.04Å
36	A	93.3	Very high	89.2	Confident	12 Å²	12	64.4 Å²	64.4	10%	0.099	35%	0.352	C	S	.	.	H	α-helix	trans	-56.9	-45.5	179.4	0	0	0	0	0	112.3	S32 V33 L40 M174 T178	S32-A36 WeakPolarHBondContact O-CB 3.39Å; S32-A36 PolarHBondContact O-N 3.47Å; V33-A36 WeakPolarHBondContact O-CB 3.13Å; V33-A36 PolarHBondContact O-N 3.49Å; A36-L40 VanDerWaalsContact O-CB 3.23Å; A36-L40 WeakPolarHBondContact O-CB 3.49Å; A36-L40 PolarHBondContact O-N 3.43Å; A36-M174 HydrophobicContact CB-CB 4.01Å; A36-M174 HydrophobicContact CB-CG 4.49Å; A36-M174 HydrophobicContact CB-SD 4.31Å; A36-T178 WeakPolarHBondContact CA-OG1 3.23Å; A36-T178 WeakPolarHBondContact CB-OG1 3.25Å; A36-T178 PolarHBondContact O-OG1 2.85Å
37	A	92.9	Very high	90.6	Very high	42 Å²	42	57.4 Å²	57.4	35%	0.347	32%	0.322	S	S	.	.	H	α-helix	trans	-65.3	-46.5	-178.6	0	0	0	0	0	111.7	V33 L34 L35 L40 L41	V33-A37 WeakPolarHBondContact O-CB 3.27Å; V33-A37 PolarHBondContact O-N 3.01Å; L34-A37 PolarHBondContact O-N 3.41Å; L35-A37 VanDerWaalsContact C-N 3.32Å; L35-A37 PolarHBondContact O-N 2.04Å; A37-L40 PolarHBondContact O-N 3.27Å; A37-L41 WeakPolarHBondContact O-CB 3.39Å; A37-L41 VanDerWaalsContact O-CG 3.23Å; A37-L41 WeakPolarHBondContact O-CG 3.23Å; A37-L41 PolarHBondContact O-N 3.04Å
38	N	95	Very high	91	Very high	108 Å²	108	58.2 Å²	58.2	58%	0.578	32%	0.321	S	S	*	.	H	α-helix	trans	-64.4	-43	179	-79.4	-83.2	0	0	0	112	L34 L35 L41 L42	L34-N38 PolarHBondContact O-N 2.99Å; L34-N38 PolarHBondContact O-ND2 3.43Å; L35-N38 PolarHBondContact O-N 3.17Å; N38-L41 PolarHBondContact O-N 3.3Å; N38-L42 WeakPolarHBondContact O-CB 3.27Å; N38-L42 PolarHBondContact O-N 3.46Å
39	V	95	Very high	91.1	Very high	29 Å²	29	58.5 Å²	58.5	18%	0.176	33%	0.325	C	S	.	.	H	α-helix	trans	-65.7	-40.5	177.4	175.8	0	0	0	0	110.9	L35 L42 A43 M69 F175 T178	L35-V39 HydrophobicContact CD1-CG2 4.17Å; L35-V39 VanDerWaalsContact O-CG2 3.3Å; L35-V39 WeakPolarHBondContact O-CG2 3.4Å; L35-V39 PolarHBondContact O-N 3Å; V39-L42 PolarHBondContact O-N 3.13Å; V39-A43 WeakPolarHBondContact O-CB 3.46Å; V39-A43 PolarHBondContact O-N 2.74Å; V39-M69 HydrophobicContact CG1-CE 3.5Å; V39-M69 VanDerWaalsContact CG1-CE 3.5Å; V39-M69 HydrophobicContact CG1-SD 4.31Å; V39-F175 HydrophobicContact CG1-CD2 4.41Å; V39-F175 HydrophobicContact CG1-CE2 4.11Å; V39-F175 HydrophobicContact CG2-CD2 4.44Å; V39-F175 HydrophobicContact CG2-CE2 4.42Å; V39-T178 HydrophobicContact CB-CG2 3.95Å; V39-T178 HydrophobicContact CG1-CG2 3.65Å
40	L	93.5	Very high	90.7	Very high	48 Å²	48	53.6 Å²	53.6	25%	0.251	31%	0.309	S	S	.	.	H	α-helix	trans	-66	-42.8	177.6	-174.4	60	0	0	0	111.3	A36 A37 L42 A43 C44 T178 L181	A36-L40 VanDerWaalsContact O-CB 3.23Å; A36-L40 WeakPolarHBondContact O-CB 3.49Å; A36-L40 PolarHBondContact O-N 3.43Å; A37-L40 PolarHBondContact O-N 3.27Å; L40-L42 VanDerWaalsContact C-N 3.35Å; L40-L42 PolarHBondContact O-N 3.28Å; L40-A43 PolarHBondContact O-N 3.16Å; L40-C44 WeakPolarHBondContact O-CB 3.18Å; L40-C44 PolarHBondContact O-N 2.91Å; L40-C44 PolarHBondContact O-SG 2.89Å; L40-T178 HydrophobicContact CB-CG2 3.71Å; L40-T178 HydrophobicContact CD1-CG2 4.21Å; L40-L181 HydrophobicContact CD1-CB 3.86Å; L40-L181 HydrophobicContact CD2-CD1 4.11Å
41	L	93.3	Very high	90	Very high	112 Å²	112	50 Å²	50	59%	0.586	30%	0.295	S	S	*	.	H	α-helix	trans	-60.9	-44.7	176.4	-73.7	170.9	0	0	0	111.2	A37 N38 A43 C44 T45	A37-L41 WeakPolarHBondContact O-CB 3.39Å; A37-L41 VanDerWaalsContact O-CG 3.23Å; A37-L41 WeakPolarHBondContact O-CG 3.23Å; A37-L41 PolarHBondContact O-N 3.04Å; N38-L41 PolarHBondContact O-N 3.3Å; L41-A43 VanDerWaalsContact C-N 3.34Å; L41-A43 PolarHBondContact O-N 3.11Å; L41-C44 PolarHBondContact O-N 3.5Å; L41-T45 WeakPolarHBondContact O-CG2 3.04Å; L41-T45 PolarHBondContact O-N 3.17Å; L41-T45 PolarHBondContact O-OG1 3.04Å
42	L	93	Very high	88.9	Confident	94 Å²	94	52 Å²	52	49%	0.492	30%	0.299	S	S	.	.	H	α-helix	trans	-60.8	-42	175.3	179	64.2	0	0	0	112.2	N38 V39 L40 T45 L46	N38-L42 WeakPolarHBondContact O-CB 3.27Å; N38-L42 PolarHBondContact O-N 3.46Å; V39-L42 PolarHBondContact O-N 3.13Å; L40-L42 VanDerWaalsContact C-N 3.35Å; L40-L42 PolarHBondContact O-N 3.28Å; L42-T45 PolarHBondContact O-OG1 3.33Å; L42-L46 HydrophobicContact CD1-CD1 4.14Å; L42-L46 HydrophobicContact CG-CD1 4.33Å; L42-L46 PolarHBondContact O-N 3.33Å
43	A	93.4	Very high	87.3	Confident	0 Å²	0	59.3 Å²	59.3	0%	0	34%	0.338	C	S	.	.	H	α-helix	trans	-64.8	-47.7	176	0	0	0	0	0	111.5	V39 L40 L41 T45 L46 I47 L65 M69 A182	V39-A43 WeakPolarHBondContact O-CB 3.46Å; V39-A43 PolarHBondContact O-N 2.74Å; L40-A43 PolarHBondContact O-N 3.16Å; L41-A43 VanDerWaalsContact C-N 3.34Å; L41-A43 PolarHBondContact O-N 3.11Å; A43-T45 VanDerWaalsContact C-N 3.33Å; A43-T45 PolarHBondContact O-N 2.69Å; A43-L46 PolarHBondContact O-N 2.89Å; A43-I47 HydrophobicContact CB-CD1 4.29Å; A43-I47 WeakPolarHBondContact O-CB 3.5Å; A43-I47 WeakPolarHBondContact O-CD1 3.42Å; A43-I47 WeakPolarHBondContact O-CG1 3.4Å; A43-I47 PolarHBondContact O-N 3.26Å; A43-L65 HydrophobicContact CB-CD2 4.05Å; A43-M69 HydrophobicContact CB-SD 4.4Å; A43-A182 HydrophobicContact CB-CB 3.69Å
44	C	90.8	Very high	85.8	Confident	36 Å²	36	66.2 Å²	66.2	24%	0.243	36%	0.363	C	S	.	.	H	α-helix	trans	-60.3	-40.5	178.7	-71.3	0	0	0	0	112.4	L40 L41 S48	L40-C44 WeakPolarHBondContact O-CB 3.18Å; L40-C44 PolarHBondContact O-N 2.91Å; L40-C44 PolarHBondContact O-SG 2.89Å; L41-C44 PolarHBondContact O-N 3.5Å; C44-S48 VanDerWaalsContact O-CB 3.27Å; C44-S48 WeakPolarHBondContact O-CB 3.3Å; C44-S48 PolarHBondContact O-N 2.98Å; C44-S48 PolarHBondContact O-OG 3.49Å
45	T	89.7	Confident	84.8	Confident	86 Å²	86	66 Å²	66	53%	0.528	37%	0.365	S	S	.	.	H	α-helix	trans	-67.4	-40.5	178.8	53	0	0	0	0	112.2	L41 L42 A43 S48 G49	L41-T45 WeakPolarHBondContact O-CG2 3.04Å; L41-T45 PolarHBondContact O-N 3.17Å; L41-T45 PolarHBondContact O-OG1 3.04Å; L42-T45 PolarHBondContact O-OG1 3.33Å; A43-T45 VanDerWaalsContact C-N 3.33Å; A43-T45 PolarHBondContact O-N 2.69Å; T45-S48 PolarHBondContact O-OG 2.98Å; T45-G49 PolarHBondContact O-N 3.48Å
46	L	89.7	Confident	83.7	Confident	45 Å²	45	66.9 Å²	66.9	24%	0.236	38%	0.383	C	S	.	.	H	α-helix	trans	-70.2	-44.3	176.8	-77	168.1	0	0	0	112.2	L42 A43 G49 G50 V57 L65	L42-L46 HydrophobicContact CD1-CD1 4.14Å; L42-L46 HydrophobicContact CG-CD1 4.33Å; L42-L46 PolarHBondContact O-N 3.33Å; A43-L46 PolarHBondContact O-N 2.89Å; L46-G49 PolarHBondContact O-N 3.47Å; L46-G50 PolarHBondContact O-N 2.91Å; L46-V57 HydrophobicContact CD2-CG1 4.29Å; L46-L65 HydrophobicContact CB-CD2 4.23Å; L46-L65 HydrophobicContact CD1-CD1 4.22Å; L46-L65 HydrophobicContact CD1-CD2 3.66Å; L46-L65 HydrophobicContact CD1-CG 4.34Å
47	I	89.7	Confident	82.8	Confident	5 Å²	5	68 Å²	68	3%	0.026	39%	0.388	C	S	.	.	H	α-helix	trans	-62.6	-48.4	178.6	-67.7	162.3	0	0	0	110.7	A43 G49 G50 A51 V62 A182 M185 A186 V189	A43-I47 HydrophobicContact CB-CD1 4.29Å; A43-I47 WeakPolarHBondContact O-CB 3.5Å; A43-I47 WeakPolarHBondContact O-CD1 3.42Å; A43-I47 WeakPolarHBondContact O-CG1 3.4Å; A43-I47 PolarHBondContact O-N 3.26Å; I47-G49 VanDerWaalsContact C-N 3.35Å; I47-G50 PolarHBondContact O-N 3.36Å; I47-A51 PolarHBondContact O-N 3.26Å; I47-A51 VanDerWaalsContact O-N 3.16Å; I47-V62 HydrophobicContact CG1-CG1 3.86Å; I47-A182 HydrophobicContact CD1-CB 4.46Å; I47-A182 WeakPolarHBondContact CD1-O 3.36Å; I47-M185 HydrophobicContact CD1-CB 4.09Å; I47-A186 HydrophobicContact CD1-CB 3.93Å; I47-A186 HydrophobicContact CG1-CB 4.12Å; I47-A186 HydrophobicContact CG2-CB 4.32Å; I47-V189 HydrophobicContact CG2-CB 4.15Å; I47-V189 HydrophobicContact CG2-CG1 4.44Å; I47-V189 HydrophobicContact CG2-CG2 3.86Å
48	S	83.7	Confident	82.1	Confident	57 Å²	57	73.6 Å²	73.6	40%	0.399	40%	0.401	S	S	.	.	H	α-helix	trans	-67.7	-35.7	177.6	57.9	0	0	0	0	112.1	C44 T45 A51 F52	C44-S48 VanDerWaalsContact O-CB 3.27Å; C44-S48 WeakPolarHBondContact O-CB 3.3Å; C44-S48 PolarHBondContact O-N 2.98Å; C44-S48 PolarHBondContact O-OG 3.49Å; T45-S48 PolarHBondContact O-OG 2.98Å; S48-A51 WeakPolarHBondContact O-CB 3.3Å; S48-A51 PolarHBondContact O-N 3.19Å; S48-F52 WeakPolarHBondContact O-CD2 3.4Å
49	G	82.8	Confident	81.2	Confident	12 Å²	12	72.4 Å²	72.4	12%	0.124	40%	0.395	C	S	.	.	H	α-helix	trans	-61.2	-42.5	173.8	0	0	0	0	0	113	T45 L46 I47 A51 F52	T45-G49 PolarHBondContact O-N 3.48Å; L46-G49 PolarHBondContact O-N 3.47Å; I47-G49 VanDerWaalsContact C-N 3.35Å; G49-A51 VanDerWaalsContact C-N 3.32Å; G49-A51 PolarHBondContact O-N 2.96Å; G49-F52 PolarHBondContact O-N 3.43Å
50	G	77.5	Confident	80.6	Confident	9 Å²	9	73.1 Å²	73.1	9%	0.093	40%	0.4	C	S	.	.	H	α-helix	trans	-68.4	-27.3	176	0	0	0	0	0	113.9	L46 I47 F52	L46-G50 PolarHBondContact O-N 2.91Å; I47-G50 PolarHBondContact O-N 3.36Å; G50-F52 PolarHBondContact O-N 3.3Å
51	A	74	Confident	80.4	Confident	32 Å²	32	74.1 Å²	74.1	26%	0.264	41%	0.405	S	S	.	.	H	α-helix	trans	-66.5	-24.8	177	0	0	0	0	0	113.5	I47 S48 G49 V189	I47-A51 PolarHBondContact O-N 3.26Å; I47-A51 VanDerWaalsContact O-N 3.16Å; S48-A51 WeakPolarHBondContact O-CB 3.3Å; S48-A51 PolarHBondContact O-N 3.19Å; G49-A51 VanDerWaalsContact C-N 3.32Å; G49-A51 PolarHBondContact O-N 2.96Å; A51-V189 HydrophobicContact CB-CG1 3.52Å
52	F	68.8	Low	80.1	Confident	143 Å²	143	69.6 Å²	69.6	63%	0.627	38%	0.382	S	S	*	.	S	Bend	trans	-106.3	106.5	-178.1	-61.8	-69	0	0	0	110.5	S48 G49 G50 K54 V55	S48-F52 WeakPolarHBondContact O-CD2 3.4Å; G49-F52 PolarHBondContact O-N 3.43Å; G50-F52 PolarHBondContact O-N 3.3Å; F52-K54 PolarHBondContact O-N 3.22Å; F52-V55 PolarHBondContact O-N 2.98Å
53	N	59.3	Low	80	Confident	154 Å²	154	66.2 Å²	66.2	82%	0.824	36%	0.364	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.7	6.5	179.1	-72.9	-22.6	0	0	0	116.4
54	K	61.7	Low	79.9	Confident	208 Å²	208	68.1 Å²	68.1	90%	0.904	38%	0.379	S	S	*	.	T	Hydrogen-bonded Turn	trans	-98.2	-1.5	178.9	-66.8	-173.1	178.8	179.4	0	113.6	F52	F52-K54 PolarHBondContact O-N 3.22Å
55	V	70.5	Confident	80.1	Confident	83 Å²	83	67.8 Å²	67.8	50%	0.503	38%	0.375	S	S	.	.	S	Bend	trans	-117.2	150.1	-174.9	-169.1	0	0	0	0	110.5	F52 V57	F52-V55 PolarHBondContact O-N 2.98Å; V55-V57 HydrophobicContact CG1-CG2 4.07Å; V55-V57 PolarHBondContact O-N 3.08Å
56	A	70.4	Confident	80.3	Confident	90 Å²	90	64 Å²	64	74%	0.744	35%	0.351	S	S	*	.	S	Bend	trans	-74.3	39.8	177.7	0	0	0	0	0	113.8
57	V	74.6	Confident	80.6	Confident	34 Å²	34	62.2 Å²	62.2	21%	0.206	34%	0.343	C	S	.	.			trans	-113.9	119	175	177.3	0	0	0	0	107.3	L46 V55 D61	L46-V57 HydrophobicContact CD2-CG1 4.29Å; V55-V57 HydrophobicContact CG1-CG2 4.07Å; V55-V57 PolarHBondContact O-N 3.08Å; V57-D61 HydrophobicContact CG1-CB 4.49Å
58	Y	77.8	Confident	80.9	Confident	160 Å²	160	65.5 Å²	65.5	63%	0.627	36%	0.363	S	S	*	.			trans	-94.1	154	-179.4	-64.4	-82.7	0	0	0	110.8	T60 D61	Y58-T60 WeakPolarHBondContact CB-OG1 3.31Å; Y58-T60 PolarHBondContact O-N 3.28Å; Y58-D61 PolarHBondContact N-OD2 3.13Å; Y58-D61 WeakPolarHBondContact O-CB 3.34Å; Y58-D61 PolarHBondContact O-N 3.48Å
59	D	75.6	Confident	81.5	Confident	84 Å²	84	63.1 Å²	63.1	45%	0.449	35%	0.345	S	S	.	.	H	α-helix	trans	-51.3	-33.9	173.8	-62.6	-28.6	0	0	0	112.4	D61 V62 F63 K136	D59-D61 PolarHBondContact O-N 3.27Å; D59-V62 PolarHBondContact O-N 3.5Å; D59-F63 HydrophobicContact CB-CD2 4.27Å; D59-F63 HydrophobicContact CB-CE2 4.09Å; D59-F63 WeakPolarHBondContact O-CD2 3.35Å; D59-F63 PolarHBondContact O-N 3.4Å; D59-K136 IonicContact OD2-NZ 3.88Å
60	T	82.9	Confident	82.2	Confident	43 Å²	43	62.5 Å²	62.5	26%	0.264	34%	0.339	S	S	.	.	H	α-helix	trans	-60	-33.7	178.2	50	0	0	0	0	112.7	Y58 A64 I135	Y58-T60 WeakPolarHBondContact CB-OG1 3.31Å; Y58-T60 PolarHBondContact O-N 3.28Å; T60-A64 VanDerWaalsContact O-CB 3.27Å; T60-A64 WeakPolarHBondContact O-CB 3.08Å; T60-A64 PolarHBondContact O-N 2.91Å; T60-I135 HydrophobicContact CG2-CG2 3.84Å
61	D	88.6	Confident	83.2	Confident	69 Å²	69	66.1 Å²	66.1	37%	0.369	36%	0.356	S	S	.	.	H	α-helix	trans	-72.1	-39.6	-179.7	-55.3	-34.4	0	0	0	110.4	V57 Y58 D59 A64 L65	V57-D61 HydrophobicContact CG1-CB 4.49Å; Y58-D61 PolarHBondContact N-OD2 3.13Å; Y58-D61 WeakPolarHBondContact O-CB 3.34Å; Y58-D61 PolarHBondContact O-N 3.48Å; D59-D61 PolarHBondContact O-N 3.27Å; D61-A64 PolarHBondContact O-N 3.43Å; D61-L65 WeakPolarHBondContact O-CB 3.14Å; D61-L65 PolarHBondContact O-N 2.89Å
62	V	88.8	Confident	84.3	Confident	18 Å²	18	69.4 Å²	69.4	11%	0.109	37%	0.369	C	S	.	.	H	α-helix	trans	-64.2	-47.8	174.3	-178.5	0	0	0	0	110.4	I47 D59 A64 L65 L66	I47-V62 HydrophobicContact CG1-CG1 3.86Å; D59-V62 PolarHBondContact O-N 3.5Å; V62-A64 VanDerWaalsContact C-N 3.33Å; V62-A64 PolarHBondContact O-N 3.41Å; V62-L65 PolarHBondContact O-N 3.17Å; V62-L66 HydrophobicContact CG1-CD1 4.11Å; V62-L66 WeakPolarHBondContact O-CG 3.47Å; V62-L66 PolarHBondContact O-N 2.96Å
63	F	90.3	Very high	85.7	Confident	23 Å²	23	62.6 Å²	62.6	10%	0.101	34%	0.339	C	S	.	.	H	α-helix	trans	-62.1	-39.5	176.3	-73.4	-60	0	0	0	112.4	D59 T67 I135 K136 H139	D59-F63 HydrophobicContact CB-CD2 4.27Å; D59-F63 HydrophobicContact CB-CE2 4.09Å; D59-F63 WeakPolarHBondContact O-CD2 3.35Å; D59-F63 PolarHBondContact O-N 3.4Å; F63-T67 VanDerWaalsContact O-CB 3.22Å; F63-T67 WeakPolarHBondContact O-CB 3.07Å; F63-T67 PolarHBondContact O-N 3.37Å; F63-T67 PolarHBondContact O-OG1 3.05Å; F63-I135 HydrophobicContact CB-CG1 4.09Å; F63-K136 HydrophobicContact CD2-CG 4Å; F63-K136 HydrophobicContact CE2-CD 4.45Å; F63-K136 HydrophobicContact CE2-CG 4.02Å; F63-H139 HydrophobicContact CB-CB 4.49Å; F63-H139 HydrophobicContact CD1-CB 4Å; F63-H139 AromaticContact CD1-CD2 3.55Å; F63-H139 AromaticContact CD1-CE1 4Å; F63-H139 AromaticContact CD1-CG 3.5Å; F63-H139 AromaticContact CD1-ND1 3.79Å; F63-H139 AromaticContact CD1-NE2 3.86Å
64	A	91.9	Very high	87.5	Confident	39 Å²	39	56 Å²	56	32%	0.322	30%	0.303	S	S	.	.	H	α-helix	trans	-63.2	-47.1	176.2	0	0	0	0	0	111.3	T60 D61 V62 T67 T68	T60-A64 VanDerWaalsContact O-CB 3.27Å; T60-A64 WeakPolarHBondContact O-CB 3.08Å; T60-A64 PolarHBondContact O-N 2.91Å; D61-A64 PolarHBondContact O-N 3.43Å; V62-A64 VanDerWaalsContact C-N 3.33Å; V62-A64 PolarHBondContact O-N 3.41Å; A64-T67 PolarHBondContact O-N 3.44Å; A64-T68 VanDerWaalsContact O-CG2 3.31Å; A64-T68 WeakPolarHBondContact O-CG2 3.3Å; A64-T68 PolarHBondContact O-N 3.25Å; A64-T68 PolarHBondContact O-OG1 3.27Å
65	L	93.9	Very high	89.2	Confident	29 Å²	29	52 Å²	52	15%	0.152	29%	0.291	C	S	.	.	H	α-helix	trans	-57	-55	176.3	-178.8	75.6	0	0	0	111.3	A43 L46 D61 V62 T67 T68 M69	A43-L65 HydrophobicContact CB-CD2 4.05Å; L46-L65 HydrophobicContact CB-CD2 4.23Å; L46-L65 HydrophobicContact CD1-CD1 4.22Å; L46-L65 HydrophobicContact CD1-CD2 3.66Å; L46-L65 HydrophobicContact CD1-CG 4.34Å; D61-L65 WeakPolarHBondContact O-CB 3.14Å; D61-L65 PolarHBondContact O-N 2.89Å; V62-L65 PolarHBondContact O-N 3.17Å; L65-T67 VanDerWaalsContact C-N 3.28Å; L65-T67 PolarHBondContact O-N 2.97Å; L65-T68 PolarHBondContact O-N 3Å; L65-T68 VanDerWaalsContact O-N 3.14Å; L65-T68 PolarHBondContact O-OG1 2.72Å; L65-M69 HydrophobicContact CD1-SD 4.47Å; L65-M69 HydrophobicContact CD2-SD 4.4Å; L65-M69 HydrophobicContact CG-SD 4.07Å; L65-M69 WeakPolarHBondContact O-CG 3.27Å; L65-M69 PolarHBondContact O-N 2.95Å
66	L	94.8	Very high	90.4	Very high	6 Å²	6	49 Å²	49	3%	0.031	27%	0.271	C	S	.	.	H	α-helix	trans	-59.4	-41.5	-178.6	-67.1	174.7	0	0	0	111.6	V62 T68 M69 M70 A182 I183 A186	V62-L66 HydrophobicContact CG1-CD1 4.11Å; V62-L66 WeakPolarHBondContact O-CG 3.47Å; V62-L66 PolarHBondContact O-N 2.96Å; L66-T68 PolarHBondContact O-N 2.9Å; L66-M69 PolarHBondContact O-N 2.88Å; L66-M70 WeakPolarHBondContact O-CG 3.49Å; L66-M70 PolarHBondContact O-N 3.4Å; L66-A182 HydrophobicContact CD2-CB 3.83Å; L66-I183 HydrophobicContact CD2-CG1 4.34Å; L66-A186 HydrophobicContact CD1-CB 3.58Å
67	T	95.3	Very high	91.6	Very high	9 Å²	9	44.7 Å²	44.7	6%	0.055	24%	0.235	C	C	.	.	H	α-helix	trans	-58.6	-48.5	175.3	-60.5	0	0	0	0	111.6	F63 A64 L65 M69 M70 L71 H139 I142	F63-T67 VanDerWaalsContact O-CB 3.22Å; F63-T67 WeakPolarHBondContact O-CB 3.07Å; F63-T67 PolarHBondContact O-N 3.37Å; F63-T67 PolarHBondContact O-OG1 3.05Å; A64-T67 PolarHBondContact O-N 3.44Å; L65-T67 VanDerWaalsContact C-N 3.28Å; L65-T67 PolarHBondContact O-N 2.97Å; T67-M69 VanDerWaalsContact C-N 3.33Å; T67-M69 PolarHBondContact O-N 3.08Å; T67-M70 PolarHBondContact O-N 3.32Å; T67-L71 HydrophobicContact CG2-CD1 4.04Å; T67-L71 HydrophobicContact CG2-CG 4.47Å; T67-L71 VanDerWaalsContact O-CG 3.32Å; T67-L71 WeakPolarHBondContact O-CG 3.48Å; T67-L71 PolarHBondContact O-N 2.9Å; T67-H139 PolarHBondContact OG1-CD2 2.93Å; T67-I142 HydrophobicContact CG2-CD1 3.36Å; T67-I142 HydrophobicContact CG2-CG2 4.27Å
68	T	95.8	Very high	92.6	Very high	73 Å²	73	46.6 Å²	46.6	45%	0.448	24%	0.244	S	C	.	.	H	α-helix	trans	-63	-40.2	178.9	60.7	0	0	0	0	112.1	A64 L65 L66 L71 L72	A64-T68 VanDerWaalsContact O-CG2 3.31Å; A64-T68 WeakPolarHBondContact O-CG2 3.3Å; A64-T68 PolarHBondContact O-N 3.25Å; A64-T68 PolarHBondContact O-OG1 3.27Å; L65-T68 PolarHBondContact O-N 3Å; L65-T68 VanDerWaalsContact O-N 3.14Å; L65-T68 PolarHBondContact O-OG1 2.72Å; L66-T68 PolarHBondContact O-N 2.9Å; T68-L71 PolarHBondContact O-N 3.29Å; T68-L72 WeakPolarHBondContact O-CB 3.03Å; T68-L72 VanDerWaalsContact O-CG 3.31Å; T68-L72 WeakPolarHBondContact O-CG 3.48Å; T68-L72 PolarHBondContact O-N 2.91Å
69	M	96.8	Very high	93.3	Very high	7 Å²	7	42.1 Å²	42.1	3%	0.034	23%	0.228	C	C	.	.	H	α-helix	trans	-62.8	-45.8	176	-68.3	179.5	67	0	0	111.8	V39 A43 L65 L66 T67 L71 L72 A73 F175 T178 T179 A182	V39-M69 HydrophobicContact CG1-CE 3.5Å; V39-M69 VanDerWaalsContact CG1-CE 3.5Å; V39-M69 HydrophobicContact CG1-SD 4.31Å; A43-M69 HydrophobicContact CB-SD 4.4Å; L65-M69 HydrophobicContact CD1-SD 4.47Å; L65-M69 HydrophobicContact CD2-SD 4.4Å; L65-M69 HydrophobicContact CG-SD 4.07Å; L65-M69 WeakPolarHBondContact O-CG 3.27Å; L65-M69 PolarHBondContact O-N 2.95Å; L66-M69 PolarHBondContact O-N 2.88Å; T67-M69 VanDerWaalsContact C-N 3.33Å; T67-M69 PolarHBondContact O-N 3.08Å; M69-L71 PolarHBondContact O-N 2.85Å; M69-L72 PolarHBondContact O-N 3.19Å; M69-A73 WeakPolarHBondContact O-CB 3.47Å; M69-A73 PolarHBondContact O-N 3.11Å; M69-F175 HydrophobicContact CB-CZ 4.32Å; M69-F175 HydrophobicContact CG-CZ 4.38Å; M69-F175 WeakPolarHBondContact O-CE1 3.2Å; M69-T178 HydrophobicContact CE-CG2 4.09Å; M69-T179 HydrophobicContact CB-CG2 3.85Å; M69-A182 HydrophobicContact CE-CB 4.08Å; M69-A182 HydrophobicContact SD-CB 4.36Å
70	M	97.7	Very high	94.1	Very high	0 Å²	0	38.3 Å²	38.3	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-60.5	-46	176.6	-73	-174.1	-70.4	0	0	112	L66 T67 L72 A73 M74 I142 Q143 F146 T179 I183	L66-M70 WeakPolarHBondContact O-CG 3.49Å; L66-M70 PolarHBondContact O-N 3.4Å; T67-M70 PolarHBondContact O-N 3.32Å; M70-L72 PolarHBondContact O-N 3.06Å; M70-A73 PolarHBondContact O-N 3.33Å; M70-M74 WeakPolarHBondContact O-CG 3.05Å; M70-M74 PolarHBondContact O-N 3.41Å; M70-I142 HydrophobicContact CB-CG2 4.28Å; M70-I142 HydrophobicContact CE-CG2 4.29Å; M70-Q143 HydrophobicContact CE-CB 4.17Å; M70-Q143 HydrophobicContact SD-CB 3.89Å; M70-Q143 HydrophobicContact SD-CG 4Å; M70-F146 HydrophobicContact CB-CB 4.22Å; M70-F146 HydrophobicContact CB-CD2 4.31Å; M70-F146 HydrophobicContact CB-CG 4.12Å; M70-F146 HydrophobicContact CG-CB 4.33Å; M70-F146 HydrophobicContact CG-CD1 3.92Å; M70-F146 HydrophobicContact CG-CD2 4.42Å; M70-F146 HydrophobicContact CG-CE1 4.31Å; M70-F146 HydrophobicContact CG-CG 3.97Å; M70-F146 HydrophobicContact SD-CB 4.17Å; M70-F146 HydrophobicContact SD-CD1 3.95Å; M70-F146 HydrophobicContact SD-CG 4.22Å; M70-T179 HydrophobicContact CG-CG2 4.02Å; M70-I183 HydrophobicContact CG-CD1 3.91Å; M70-I183 HydrophobicContact SD-CD1 3.89Å
71	L	97.4	Very high	94.5	Very high	84 Å²	84	37.7 Å²	37.7	44%	0.44	20%	0.202	S	C	.	.	H	α-helix	trans	-60.6	-44.8	178.2	-70.4	171	0	0	0	112	T67 T68 M69 M74 L75 I142	T67-L71 HydrophobicContact CG2-CD1 4.04Å; T67-L71 HydrophobicContact CG2-CG 4.47Å; T67-L71 VanDerWaalsContact O-CG 3.32Å; T67-L71 WeakPolarHBondContact O-CG 3.48Å; T67-L71 PolarHBondContact O-N 2.9Å; T68-L71 PolarHBondContact O-N 3.29Å; M69-L71 PolarHBondContact O-N 2.85Å; L71-M74 HydrophobicContact CD2-CE 3.69Å; L71-M74 HydrophobicContact CG-CE 4.49Å; L71-M74 PolarHBondContact O-N 2.81Å; L71-L75 WeakPolarHBondContact O-CB 3.37Å; L71-L75 PolarHBondContact O-N 3.18Å; L71-I142 HydrophobicContact CD2-CD1 4.45Å; L71-I142 HydrophobicContact CD2-CG2 4.07Å; L71-I142 HydrophobicContact CG-CG2 4.22Å
72	L	97.3	Very high	94.5	Very high	101 Å²	101	38.8 Å²	38.8	53%	0.529	21%	0.207	S	C	.	.	H	α-helix	trans	-64.4	-40.2	176.9	-71.6	173.2	0	0	0	111.9	T68 M69 M70 L75 W76 F175	T68-L72 WeakPolarHBondContact O-CB 3.03Å; T68-L72 VanDerWaalsContact O-CG 3.31Å; T68-L72 WeakPolarHBondContact O-CG 3.48Å; T68-L72 PolarHBondContact O-N 2.91Å; M69-L72 PolarHBondContact O-N 3.19Å; M70-L72 PolarHBondContact O-N 3.06Å; L72-L75 PolarHBondContact O-N 3.06Å; L72-W76 PolarHBondContact O-N 3.45Å; L72-W76 VanDerWaalsContact O-N 3.1Å; L72-F175 HydrophobicContact CB-CE1 3.61Å; L72-F175 HydrophobicContact CB-CZ 3.8Å; L72-F175 HydrophobicContact CD1-CZ 3.96Å
73	A	97.4	Very high	94.4	Very high	0 Å²	0	46.2 Å²	46.2	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-65.3	-45.5	176.2	0	0	0	0	0	111.3	M69 M70 L75 W76 I77 F146 F175 T176	M69-A73 WeakPolarHBondContact O-CB 3.47Å; M69-A73 PolarHBondContact O-N 3.11Å; M70-A73 PolarHBondContact O-N 3.33Å; A73-L75 VanDerWaalsContact C-N 3.34Å; A73-L75 PolarHBondContact O-N 3.47Å; A73-W76 PolarHBondContact O-N 3.2Å; A73-I77 VanDerWaalsContact O-CG1 3.28Å; A73-I77 WeakPolarHBondContact O-CG1 3.37Å; A73-I77 PolarHBondContact O-N 3.3Å; A73-F146 HydrophobicContact CB-CE2 3.77Å; A73-F175 HydrophobicContact CB-CD1 4.22Å; A73-F175 HydrophobicContact CB-CE1 4.13Å; A73-T176 HydrophobicContact CB-CG2 4.32Å
74	M	97.5	Very high	94	Very high	16 Å²	16	45.2 Å²	45.2	8%	0.079	23%	0.229	C	C	.	.	H	α-helix	trans	-58.8	-44.6	174.9	-72.2	-164.4	-70.9	0	0	112	M70 L71 W76 I77 L78 I142 V145 F146 I149	M70-M74 WeakPolarHBondContact O-CG 3.05Å; M70-M74 PolarHBondContact O-N 3.41Å; L71-M74 HydrophobicContact CD2-CE 3.69Å; L71-M74 HydrophobicContact CG-CE 4.49Å; L71-M74 PolarHBondContact O-N 2.81Å; M74-W76 VanDerWaalsContact C-N 3.3Å; M74-W76 PolarHBondContact O-N 3.24Å; M74-I77 PolarHBondContact O-N 3.19Å; M74-L78 WeakPolarHBondContact O-CB 3.3Å; M74-L78 VanDerWaalsContact O-CG 3.27Å; M74-L78 WeakPolarHBondContact O-CG 3.37Å; M74-L78 PolarHBondContact O-N 3.36Å; M74-I142 HydrophobicContact CE-CG2 4.03Å; M74-V145 HydrophobicContact CE-CG1 4.46Å; M74-V145 HydrophobicContact SD-CB 4.27Å; M74-V145 HydrophobicContact SD-CG1 3.75Å; M74-F146 HydrophobicContact CG-CB 4.07Å; M74-F146 HydrophobicContact CG-CD2 3.66Å; M74-F146 HydrophobicContact CG-CG 4.37Å; M74-F146 WeakPolarHBondContact SD-CA 3.27Å; M74-F146 HydrophobicContact SD-CB 3.89Å; M74-I149 HydrophobicContact CG-CD1 4.38Å; M74-I149 HydrophobicContact SD-CD1 3.79Å
75	L	97	Very high	93.5	Very high	123 Å²	123	46 Å²	46	64%	0.644	23%	0.23	S	C	*	.	H	α-helix	trans	-59.2	-43	178.3	-178.6	133.5	0	0	0	111.4	L71 L72 A73 F79	L71-L75 WeakPolarHBondContact O-CB 3.37Å; L71-L75 PolarHBondContact O-N 3.18Å; L72-L75 PolarHBondContact O-N 3.06Å; A73-L75 VanDerWaalsContact C-N 3.34Å; A73-L75 PolarHBondContact O-N 3.47Å; L75-F79 WeakPolarHBondContact O-CB 3.42Å; L75-F79 PolarHBondContact O-N 2.9Å
76	W	96.7	Very high	92.8	Very high	21 Å²	21	53.5 Å²	53.5	8%	0.08	26%	0.256	C	S	.	.	H	α-helix	trans	-67.1	-43.2	174.9	175.6	82.5	0	0	0	112.7	L72 A73 M74 L78 F79 Y80 F153 L168 T169 G172 L173	L72-W76 PolarHBondContact O-N 3.45Å; L72-W76 VanDerWaalsContact O-N 3.1Å; A73-W76 PolarHBondContact O-N 3.2Å; M74-W76 VanDerWaalsContact C-N 3.3Å; M74-W76 PolarHBondContact O-N 3.24Å; W76-L78 PolarHBondContact O-N 2.93Å; W76-F79 WeakPolarHBondContact O-CB 3.45Å; W76-F79 PolarHBondContact O-N 3.18Å; W76-Y80 HydrophobicContact CH2-CD2 4.48Å; W76-Y80 HydrophobicContact CZ2-CD2 4.2Å; W76-Y80 WeakPolarHBondContact O-CB 3.36Å; W76-Y80 PolarHBondContact O-N 3.07Å; W76-F153 HydrophobicContact CH2-CZ 4.06Å; W76-F153 HydrophobicContact CZ3-CE1 4.28Å; W76-F153 HydrophobicContact CZ3-CZ 4.11Å; W76-L168 PolarHBondContact NE1-O 3.29Å; W76-T169 HydrophobicContact CZ2-CG2 4.31Å; W76-G172 VanDerWaalsContact CE2-CA 3.45Å; W76-L173 HydrophobicContact CH2-CB 4.41Å; W76-L173 HydrophobicContact CH2-CD2 3.58Å; W76-L173 HydrophobicContact CH2-CG 3.61Å; W76-L173 HydrophobicContact CZ2-CG 4.15Å; W76-L173 HydrophobicContact CZ3-CD2 4.17Å; W76-L173 HydrophobicContact CZ3-CG 4.47Å
77	I	96.1	Very high	92	Very high	0 Å²	0	56.1 Å²	56.1	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-60.4	-45.8	177.7	-68.8	166.2	0	0	0	110.6	A73 M74 Y80 L81 F146 I149 Q150 F153 T176	A73-I77 VanDerWaalsContact O-CG1 3.28Å; A73-I77 WeakPolarHBondContact O-CG1 3.37Å; A73-I77 PolarHBondContact O-N 3.3Å; M74-I77 PolarHBondContact O-N 3.19Å; I77-Y80 WeakPolarHBondContact O-CB 3.49Å; I77-Y80 PolarHBondContact O-N 3.38Å; I77-L81 HydrophobicContact CG2-CD1 3.89Å; I77-L81 HydrophobicContact CG2-CG 4.34Å; I77-L81 WeakPolarHBondContact O-CG 3.36Å; I77-L81 PolarHBondContact O-N 3.5Å; I77-F146 HydrophobicContact CD1-CE2 4.46Å; I77-I149 HydrophobicContact CB-CG2 4.24Å; I77-I149 HydrophobicContact CG2-CG2 3.67Å; I77-Q150 HydrophobicContact CD1-CB 4.25Å; I77-Q150 HydrophobicContact CD1-CG 4.44Å; I77-F153 HydrophobicContact CD1-CD1 4.44Å; I77-F153 HydrophobicContact CG1-CD1 4.25Å; I77-F153 HydrophobicContact CG1-CG 4.48Å; I77-F153 HydrophobicContact CG2-CB 3.51Å; I77-F153 HydrophobicContact CG2-CD1 4.29Å; I77-F153 HydrophobicContact CG2-CD2 4.11Å; I77-F153 HydrophobicContact CG2-CG 3.71Å; I77-T176 HydrophobicContact CD1-CG2 4.1Å
78	L	95.1	Very high	90.2	Very high	73 Å²	73	61.3 Å²	61.3	38%	0.382	31%	0.311	S	S	.	.	H	α-helix	trans	-62.4	-43.8	177.2	-71.4	170.2	0	0	0	111.2	M74 W76 Y80 L81 L82 I149	M74-L78 WeakPolarHBondContact O-CB 3.3Å; M74-L78 VanDerWaalsContact O-CG 3.27Å; M74-L78 WeakPolarHBondContact O-CG 3.37Å; M74-L78 PolarHBondContact O-N 3.36Å; W76-L78 PolarHBondContact O-N 2.93Å; L78-Y80 VanDerWaalsContact C-N 3.3Å; L78-Y80 PolarHBondContact O-N 3.39Å; L78-L81 PolarHBondContact O-N 2.86Å; L78-L82 VanDerWaalsContact O-CB 3.25Å; L78-L82 WeakPolarHBondContact O-CB 3.48Å; L78-L82 VanDerWaalsContact O-CG 3.23Å; L78-L82 WeakPolarHBondContact O-CG 3.42Å; L78-L82 PolarHBondContact O-N 3.42Å; L78-I149 HydrophobicContact CD1-CD1 4.43Å; L78-I149 HydrophobicContact CD2-CD1 4.4Å; L78-I149 HydrophobicContact CD2-CG2 4.43Å
79	F	93.4	Very high	88.5	Confident	67 Å²	67	63.1 Å²	63.1	29%	0.294	33%	0.325	S	S	.	.	H	α-helix	trans	-57.5	-43.9	173.1	171.8	-93.4	0	0	0	111.8	L75 W76 R83 L168	L75-F79 WeakPolarHBondContact O-CB 3.42Å; L75-F79 PolarHBondContact O-N 2.9Å; W76-F79 WeakPolarHBondContact O-CB 3.45Å; W76-F79 PolarHBondContact O-N 3.18Å; F79-R83 HydrophobicContact CD2-CG 4.46Å; F79-R83 HydrophobicContact CE2-CB 4.38Å; F79-R83 HydrophobicContact CE2-CG 4.41Å; F79-R83 WeakPolarHBondContact O-CB 3.32Å; F79-R83 PolarHBondContact O-N 3.36Å; F79-L168 HydrophobicContact CD1-CD2 4.33Å; F79-L168 HydrophobicContact CE1-CD2 3.56Å; F79-L168 HydrophobicContact CZ-CD2 4.07Å
80	Y	91.6	Very high	86.9	Confident	3 Å²	3	62.8 Å²	62.8	1%	0.012	32%	0.324	C	S	.	.	I	π-helix	trans	-62.2	-49.7	178	179.1	-83.6	0	0	0	112.1	W76 I77 L78 T84 V85 F153 D160 V162 T169	W76-Y80 HydrophobicContact CH2-CD2 4.48Å; W76-Y80 HydrophobicContact CZ2-CD2 4.2Å; W76-Y80 WeakPolarHBondContact O-CB 3.36Å; W76-Y80 PolarHBondContact O-N 3.07Å; I77-Y80 WeakPolarHBondContact O-CB 3.49Å; I77-Y80 PolarHBondContact O-N 3.38Å; L78-Y80 VanDerWaalsContact C-N 3.3Å; L78-Y80 PolarHBondContact O-N 3.39Å; Y80-T84 HydrophobicContact CD2-CG2 3.89Å; Y80-T84 HydrophobicContact CE2-CG2 3.79Å; Y80-T84 WeakPolarHBondContact O-CA 3.45Å; Y80-T84 VanDerWaalsContact O-CB 3.28Å; Y80-T84 WeakPolarHBondContact O-CB 3.45Å; Y80-T84 PolarHBondContact O-N 2.87Å; Y80-V85 HydrophobicContact CD1-CG2 3.81Å; Y80-V85 HydrophobicContact CE1-CG2 3.3Å; Y80-V85 PolarHBondContact O-N 2.99Å; Y80-F153 AromaticContact CD1-CD2 3.99Å; Y80-F153 HydrophobicContact CD1-CD2 3.99Å; Y80-F153 AromaticContact CD1-CE2 3.43Å; Y80-F153 HydrophobicContact CD1-CE2 3.43Å; Y80-F153 VanDerWaalsContact CD1-CE2 3.43Å; Y80-F153 HydrophobicContact CD1-CZ 4.46Å; Y80-F153 HydrophobicContact CE1-CD2 4.26Å; Y80-F153 AromaticContact CE1-CE2 3.54Å; Y80-F153 HydrophobicContact CE1-CE2 3.54Å; Y80-F153 HydrophobicContact CG-CE2 4.13Å; Y80-D160 PolarHBondContact OH-OD2 3.18Å; Y80-V162 HydrophobicContact CE2-CG1 4.41Å; Y80-V162 HydrophobicContact CE2-CG2 3.81Å; Y80-V162 WeakPolarHBondContact OH-CG2 3.47Å; Y80-T169 HydrophobicContact CD2-CG2 4.44Å; Y80-T169 HydrophobicContact CE2-CG2 4.12Å
81	L	90.8	Very high	85.5	Confident	30 Å²	30	64.7 Å²	64.7	16%	0.157	34%	0.335	C	S	.	.	I	π-helix	trans	-66.3	-41.8	-178.3	-71.2	173.6	0	0	0	112.4	I77 L78 Y152 F153	I77-L81 HydrophobicContact CG2-CD1 3.89Å; I77-L81 HydrophobicContact CG2-CG 4.34Å; I77-L81 WeakPolarHBondContact O-CG 3.36Å; I77-L81 PolarHBondContact O-N 3.5Å; L78-L81 PolarHBondContact O-N 2.86Å; L81-Y152 HydrophobicContact CD1-CD1 3.85Å; L81-Y152 HydrophobicContact CD1-CE1 3.99Å; L81-Y152 HydrophobicContact CD2-CE1 4.36Å; L81-F153 HydrophobicContact CD1-CB 4.29Å; L81-F153 HydrophobicContact CD2-CD2 4.02Å; L81-F153 HydrophobicContact CG-CD2 4.26Å
82	L	89.3	Confident	83.7	Confident	92 Å²	92	63.7 Å²	63.7	48%	0.482	33%	0.334	S	S	.	.	I	π-helix	trans	-81.2	-32.9	-174.8	-65.1	174.7	0	0	0	113.1	L78 R86	L78-L82 VanDerWaalsContact O-CB 3.25Å; L78-L82 WeakPolarHBondContact O-CB 3.48Å; L78-L82 VanDerWaalsContact O-CG 3.23Å; L78-L82 WeakPolarHBondContact O-CG 3.42Å; L78-L82 PolarHBondContact O-N 3.42Å; L82-R86 VanDerWaalsContact O-CD 3.25Å; L82-R86 WeakPolarHBondContact O-CD 3.5Å
83	R	86.2	Confident	82.3	Confident	174 Å²	174	63.4 Å²	63.4	66%	0.657	33%	0.327	S	S	*	.	I	π-helix	trans	-111	-57.8	-177.6	-64.7	-154.5	178.3	-166.4	1.3	113.1	F79 V85 R86 C87	F79-R83 HydrophobicContact CD2-CG 4.46Å; F79-R83 HydrophobicContact CE2-CB 4.38Å; F79-R83 HydrophobicContact CE2-CG 4.41Å; F79-R83 WeakPolarHBondContact O-CB 3.32Å; F79-R83 PolarHBondContact O-N 3.36Å; R83-V85 PolarHBondContact O-N 2.77Å; R83-R86 PolarHBondContact O-N 3.19Å; R83-C87 PolarHBondContact O-N 3.34Å; R83-C87 PolarHBondContact O-SG 3.36Å; R83-C87 VanDerWaalsContact O-SG 3.4Å
84	T	82.8	Confident	81.1	Confident	2 Å²	2	72 Å²	72	1%	0.012	36%	0.359	C	S	.	.	I	π-helix	trans	-62.5	-45.6	-170.5	-54.2	0	0	0	0	112.2	Y80 R86 C87 A90 V162	Y80-T84 HydrophobicContact CD2-CG2 3.89Å; Y80-T84 HydrophobicContact CE2-CG2 3.79Å; Y80-T84 WeakPolarHBondContact O-CA 3.45Å; Y80-T84 VanDerWaalsContact O-CB 3.28Å; Y80-T84 WeakPolarHBondContact O-CB 3.45Å; Y80-T84 PolarHBondContact O-N 2.87Å; T84-R86 VanDerWaalsContact C-N 3.34Å; T84-R86 PolarHBondContact O-N 2.66Å; T84-C87 PolarHBondContact O-N 3.25Å; T84-A90 WeakPolarHBondContact O-CB 3.21Å; T84-V162 HydrophobicContact CG2-CG1 4.18Å
85	V	79.9	Confident	79.7	Confident	57 Å²	57	71.3 Å²	71.3	35%	0.345	36%	0.355	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.4	-30.9	-180	177.5	0	0	0	0	112.5	Y80 R83 C87	Y80-V85 HydrophobicContact CD1-CG2 3.81Å; Y80-V85 HydrophobicContact CE1-CG2 3.3Å; Y80-V85 PolarHBondContact O-N 2.99Å; R83-V85 PolarHBondContact O-N 2.77Å; V85-C87 VanDerWaalsContact C-N 3.34Å
86	R	80.4	Confident	78.1	Confident	186 Å²	186	69.3 Å²	69.3	70%	0.702	36%	0.357	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.8	-14.7	-178.8	-64.6	-167.5	-175.2	167.1	-3.4	113.8	L82 R83 T84 S88	L82-R86 VanDerWaalsContact O-CD 3.25Å; L82-R86 WeakPolarHBondContact O-CD 3.5Å; R83-R86 PolarHBondContact O-N 3.19Å; T84-R86 VanDerWaalsContact C-N 3.34Å; T84-R86 PolarHBondContact O-N 2.66Å; R86-S88 PolarHBondContact O-N 2.73Å
87	C	78.3	Confident	76.7	Confident	60 Å²	60	73.7 Å²	73.7	41%	0.405	38%	0.378	S	S	.	.	S	Bend	trans	-69.4	121.1	174	-73.7	0	0	0	0	110.6	R83 T84 V85 C89 A90	R83-C87 PolarHBondContact O-N 3.34Å; R83-C87 PolarHBondContact O-SG 3.36Å; R83-C87 VanDerWaalsContact O-SG 3.4Å; T84-C87 PolarHBondContact O-N 3.25Å; V85-C87 VanDerWaalsContact C-N 3.34Å; C87-C89 PolarHBondContact O-N 2.98Å; C87-A90 HydrophobicContact CB-CB 3.95Å; C87-A90 VanDerWaalsContact O-CB 3.26Å; C87-A90 WeakPolarHBondContact O-CB 3.5Å; C87-A90 PolarHBondContact O-N 3.41Å
88	S	55.9	Low	75.3	Confident	118 Å²	118	73.7 Å²	73.7	83%	0.825	38%	0.378	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55	130.4	172.4	-67	0	0	0	0	109.5	R86	R86-S88 PolarHBondContact O-N 2.73Å
89	C	61.6	Low	74	Confident	111 Å²	111	70.4 Å²	70.4	75%	0.75	36%	0.362	S	S	*	.	T	Hydrogen-bonded Turn	trans	74.3	9.6	-174.4	-50.8	0	0	0	0	117.5	C87	C87-C89 PolarHBondContact O-N 2.98Å
90	A	62.8	Low	73	Confident	1 Å²	1	69.2 Å²	69.2	1%	0.008	36%	0.361	C	S	.	.	S	Bend	trans	-72.1	-32	178.3	0	0	0	0	0	114.7	T84 C87 P92 H163 V164	T84-A90 WeakPolarHBondContact O-CB 3.21Å; C87-A90 HydrophobicContact CB-CB 3.95Å; C87-A90 VanDerWaalsContact O-CB 3.26Å; C87-A90 WeakPolarHBondContact O-CB 3.5Å; C87-A90 PolarHBondContact O-N 3.41Å; A90-P92 WeakPolarHBondContact O-CD 3.22Å; A90-H163 PolarHBondContact O-N 3.48Å; A90-V164 HydrophobicContact CB-CB 4.13Å; A90-V164 HydrophobicContact CB-CG2 4.03Å
91	V	67.4	Low	72.3	Confident	40 Å²	40	75.8 Å²	75.8	24%	0.242	40%	0.395	C	S	.	.			trans	-125.5	76.2	177.3	-172.2	0	0	0	0	109.3	Y93 D160	V91-Y93 VanDerWaalsContact C-N 3.26Å; V91-Y93 WeakPolarHBondContact CG1-O 3.35Å; V91-Y93 PolarHBondContact O-N 3.2Å; V91-D160 HydrophobicContact CG1-CB 3.6Å; V91-D160 HydrophobicContact CG2-CB 4.03Å
92	P	60.3	Low	71.5	Confident	63 Å²	63	77.8 Å²	77.8	41%	0.409	40%	0.4	S	S	.	.			trans	-71.3	-20.7	-177.3	24.9	-30.6	0	0	0	113.2	A90 H163	A90-P92 WeakPolarHBondContact O-CD 3.22Å; P92-H163 HydrophobicContact CG-CB 4.18Å
93	Y	67.3	Low	70.9	Confident	95 Å²	95	74.1 Å²	74.1	37%	0.373	38%	0.381	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.8	148	-177	-54.4	-74.1	0	0	0	111.5	V91 C161 F268	V91-Y93 VanDerWaalsContact C-N 3.26Å; V91-Y93 WeakPolarHBondContact CG1-O 3.35Å; V91-Y93 PolarHBondContact O-N 3.2Å; Y93-C161 VanDerWaalsContact O-CB 3.3Å; Y93-C161 WeakPolarHBondContact O-CB 3.22Å; Y93-C161 PolarHBondContact O-N 3.41Å; Y93-F268 HydrophobicContact CE2-CD1 4.5Å
94	R	71.8	Confident	70.8	Confident	179 Å²	179	67.4 Å²	67.4	68%	0.675	36%	0.356	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-115.9	130.3	168.9	-75	-178.2	173	166.2	1.1	109.5	A96 K159 D160	R94-A96 PolarHBondContact O-N 3.41Å; R94-K159 VanDerWaalsContact CA-O 3.24Å; R94-K159 WeakPolarHBondContact CA-O 3.36Å; R94-K159 HydrophobicContact CB-CB 4.21Å; R94-K159 HydrophobicContact CG-CB 4.26Å; R94-D160 IonicContact NE-OD1 3.62Å
95	D	68.8	Low	71	Confident	2 Å²	2	69 Å²	69	1%	0.011	37%	0.373	C	S	.	.			trans	-78.2	114.1	174.2	-177.6	2.8	0	0	0	109.2	H97 A98 K159 N264 R267 T364	D95-H97 PolarHBondContact O-N 3.02Å; D95-H97 PolarHBondContact OD1-N 3.49Å; D95-H97 IonicContact OD1-ND1 3.89Å; D95-A98 HydrophobicContact CB-CB 3.66Å; D95-A98 PolarHBondContact O-N 3.29Å; D95-K159 PolarHBondContact N-O 3.48Å; D95-N264 PolarHBondContact OD2-ND2 2.99Å; D95-R267 IonicContact OD1-NH2 3.46Å; D95-R267 IonicContact OD2-CZ 3.23Å; D95-R267 IonicContact OD2-NH1 2.85Å; D95-R267 IonicContact OD2-NH2 2.88Å; D95-R267 PolarHBondContact OD2-NH2 3.33Å; D95-T364 PolarHBondContact OD2-OG1 3.42Å
96	A	63.5	Low	71.2	Confident	82 Å²	82	66.6 Å²	66.6	68%	0.678	36%	0.36	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.9	-27.9	179.6	0	0	0	0	0	112.8	R94	R94-A96 PolarHBondContact O-N 3.41Å
97	H	66.8	Low	71.6	Confident	112 Å²	112	57.8 Å²	57.8	52%	0.519	33%	0.326	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.5	-11.7	-179.8	-57.7	84	0	0	0	112.6	D95 T364	D95-H97 PolarHBondContact O-N 3.02Å; D95-H97 PolarHBondContact OD1-N 3.49Å; D95-H97 IonicContact OD1-ND1 3.89Å; H97-T364 HydrophobicContact CB-CG2 4.07Å
98	A	67.8	Low	72.3	Confident	1 Å²	1	57.2 Å²	57.2	1%	0.008	32%	0.321	C	S	.	.	S	Bend	trans	-84.7	139.6	179.2	0	0	0	0	0	111.7	D95 K159 V260	D95-A98 HydrophobicContact CB-CB 3.66Å; D95-A98 PolarHBondContact O-N 3.29Å; A98-K159 VanDerWaalsContact O-CE 3.3Å; A98-K159 WeakPolarHBondContact O-CE 3.47Å; A98-K159 WeakPolarHBondContact O-CG 3.11Å; A98-V260 HydrophobicContact CB-CG1 3.96Å
99	G	66.4	Low	74	Confident	4 Å²	4	55.8 Å²	55.8	4%	0.041	30%	0.303	C	S	.	.	S	Bend	trans	53.8	58.2	177.4	0	0	0	0	0	113.3	R104	G99-R104 PolarHBondContact O-NE 2.94Å
100	P	73.8	Confident	75.4	Confident	42 Å²	42	50.6 Å²	50.6	27%	0.273	27%	0.268	S	S	.	.			trans	-59.7	158.5	176	28.7	-37.3	0	0	0	111.5	W102 L103 R104	P100-W102 VanDerWaalsContact C-N 3.31Å; P100-W102 VanDerWaalsContact CB-NE1 3.29Å; P100-W102 HydrophobicContact CG-CZ2 4.24Å; P100-W102 PolarHBondContact O-N 2.99Å; P100-L103 HydrophobicContact CG-CB 3.95Å; P100-L103 WeakPolarHBondContact O-CB 3.31Å; P100-L103 PolarHBondContact O-N 3.44Å; P100-L103 VanDerWaalsContact O-N 3.07Å; P100-R104 PolarHBondContact O-N 3.48Å
101	I	75.9	Confident	76.9	Confident	140 Å²	140	50.6 Å²	50.6	72%	0.718	27%	0.269	S	S	*	.	H	α-helix	trans	-58.3	-41.3	-167.3	-67.2	165	0	0	0	112.2	R104 G105	I101-R104 PolarHBondContact O-N 3.46Å; I101-G105 PolarHBondContact O-N 2.95Å
102	W	74.3	Confident	78.2	Confident	72 Å²	72	53.1 Å²	53.1	27%	0.273	28%	0.28	S	S	.	.	H	α-helix	trans	-63.6	-40	178	67.3	-77.6	0	0	0	112.7	P100 R104 G105 G106 M549 S553	P100-W102 VanDerWaalsContact C-N 3.31Å; P100-W102 VanDerWaalsContact CB-NE1 3.29Å; P100-W102 HydrophobicContact CG-CZ2 4.24Å; P100-W102 PolarHBondContact O-N 2.99Å; W102-R104 VanDerWaalsContact C-N 3.3Å; W102-R104 PolarHBondContact O-N 3.14Å; W102-G105 PolarHBondContact O-N 3.33Å; W102-G106 PolarHBondContact O-N 3Å; W102-M549 VanDerWaalsContact CZ3-O 3.31Å; W102-M549 WeakPolarHBondContact CZ3-O 3.42Å; W102-S553 VanDerWaalsContact CD2-OG 3.24Å; W102-S553 WeakPolarHBondContact CZ2-OG 3.45Å; W102-S553 PolarHBondContact NE1-OG 3.32Å
103	L	77.3	Confident	79.8	Confident	15 Å²	15	51.2 Å²	51.2	8%	0.079	27%	0.267	C	S	.	.	H	α-helix	trans	-63.4	-39.3	177.5	-171	72.1	0	0	0	110.8	P100 L107 F253 M257	P100-L103 HydrophobicContact CG-CB 3.95Å; P100-L103 WeakPolarHBondContact O-CB 3.31Å; P100-L103 PolarHBondContact O-N 3.44Å; P100-L103 VanDerWaalsContact O-N 3.07Å; L103-L107 WeakPolarHBondContact O-CB 3.5Å; L103-L107 PolarHBondContact O-N 2.98Å; L103-F253 HydrophobicContact CD1-CD1 3.69Å; L103-F253 HydrophobicContact CD1-CE1 3.78Å; L103-M257 HydrophobicContact CD2-CE 4.49Å; L103-M257 HydrophobicContact CD2-CG 3.51Å; L103-M257 HydrophobicContact CD2-SD 4.05Å; L103-M257 HydrophobicContact CG-CG 3.91Å; L103-M257 HydrophobicContact CG-SD 3.91Å
104	R	84.5	Confident	81.1	Confident	34 Å²	34	46.7 Å²	46.7	13%	0.128	25%	0.25	C	C	.	.	H	α-helix	trans	-69.2	-39.7	174	-61.1	179.2	-177.4	-144.8	-16.1	112.3	G99 P100 I101 W102 L107 V108 W155 K159 M257	G99-R104 PolarHBondContact O-NE 2.94Å; P100-R104 PolarHBondContact O-N 3.48Å; I101-R104 PolarHBondContact O-N 3.46Å; W102-R104 VanDerWaalsContact C-N 3.3Å; W102-R104 PolarHBondContact O-N 3.14Å; R104-L107 WeakPolarHBondContact O-CB 3.41Å; R104-L107 PolarHBondContact O-N 3.48Å; R104-V108 WeakPolarHBondContact O-CG2 3.09Å; R104-V108 PolarHBondContact O-N 2.97Å; R104-V108 VanDerWaalsContact O-N 3.11Å; R104-W155 HydrophobicContact CB-CE3 3.67Å; R104-W155 HydrophobicContact CB-CZ3 3.58Å; R104-W155 VanDerWaalsContact CZ-O 3.27Å; R104-W155 PolarHBondContact NH1-O 2.67Å; R104-K159 VanDerWaalsContact NH2-CG 3.26Å; R104-M257 HydrophobicContact CG-CE 4.3Å
105	G	85.6	Confident	82.2	Confident	36 Å²	36	40.2 Å²	40.2	37%	0.371	23%	0.228	S	C	.	.	H	α-helix	trans	-62.8	-46.2	175.6	0	0	0	0	0	112.2	I101 W102 V108 L109	I101-G105 PolarHBondContact O-N 2.95Å; W102-G105 PolarHBondContact O-N 3.33Å; G105-V108 PolarHBondContact O-N 3.36Å; G105-L109 PolarHBondContact O-N 2.97Å
106	G	84.5	Confident	83.5	Confident	6 Å²	6	43.4 Å²	43.4	6%	0.062	25%	0.245	C	C	.	.	H	α-helix	trans	-59.8	-44.7	174	0	0	0	0	0	112.3	W102 V108 L109 F110	W102-G106 PolarHBondContact O-N 3Å; G106-V108 VanDerWaalsContact C-N 3.32Å; G106-V108 PolarHBondContact O-N 3.4Å; G106-L109 PolarHBondContact O-N 3.04Å; G106-F110 WeakPolarHBondContact O-CD2 3.38Å; G106-F110 PolarHBondContact O-N 3.32Å
107	L	89.9	Confident	84.8	Confident	0 Å²	0	39.5 Å²	39.5	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-55.5	-45.4	174.8	-178.1	78.4	0	0	0	112.3	L103 R104 G111 T151 L154 Y250 A254 M257	L103-L107 WeakPolarHBondContact O-CB 3.5Å; L103-L107 PolarHBondContact O-N 2.98Å; R104-L107 WeakPolarHBondContact O-CB 3.41Å; R104-L107 PolarHBondContact O-N 3.48Å; L107-G111 PolarHBondContact O-N 3.28Å; L107-T151 HydrophobicContact CD2-CG2 4.28Å; L107-T151 HydrophobicContact CG-CG2 4.36Å; L107-L154 HydrophobicContact CD1-CD1 3.94Å; L107-L154 HydrophobicContact CD2-CB 3.45Å; L107-L154 VanDerWaalsContact CD2-CB 3.45Å; L107-L154 HydrophobicContact CD2-CD1 3.9Å; L107-L154 HydrophobicContact CD2-CG 4.33Å; L107-Y250 HydrophobicContact CD1-CD2 4.1Å; L107-Y250 HydrophobicContact CD1-CE2 3.67Å; L107-Y250 HydrophobicContact CG-CE2 4.2Å; L107-A254 HydrophobicContact CD1-CB 4.03Å; L107-M257 HydrophobicContact CB-SD 4.22Å; L107-M257 HydrophobicContact CD1-SD 4.3Å; L107-M257 HydrophobicContact CD2-CE 4.33Å; L107-M257 HydrophobicContact CD2-SD 3.93Å; L107-M257 HydrophobicContact CG-SD 4.38Å
108	V	92.4	Very high	86.1	Confident	48 Å²	48	34.2 Å²	34.2	29%	0.291	19%	0.188	S	C	.	.	H	α-helix	trans	-68.3	-43	179.2	173.2	0	0	0	0	111.3	R104 G105 G106 G111 I112 T151 W155	R104-V108 WeakPolarHBondContact O-CG2 3.09Å; R104-V108 PolarHBondContact O-N 2.97Å; R104-V108 VanDerWaalsContact O-N 3.11Å; G105-V108 PolarHBondContact O-N 3.36Å; G106-V108 VanDerWaalsContact C-N 3.32Å; G106-V108 PolarHBondContact O-N 3.4Å; V108-G111 PolarHBondContact O-N 3.06Å; V108-I112 HydrophobicContact CG1-CD1 3.84Å; V108-I112 HydrophobicContact CG1-CG1 4.42Å; V108-I112 VanDerWaalsContact O-CG1 3.3Å; V108-I112 WeakPolarHBondContact O-CG1 3.36Å; V108-I112 PolarHBondContact O-N 3.17Å; V108-T151 HydrophobicContact CG2-CG2 4.01Å; V108-W155 HydrophobicContact CG2-CE3 3.61Å; V108-W155 HydrophobicContact CG2-CZ3 3.82Å
109	L	90.4	Very high	87.3	Confident	88 Å²	88	39.6 Å²	39.6	46%	0.461	22%	0.216	S	C	.	.	H	α-helix	trans	-58.5	-54.7	177.9	176.8	64.8	0	0	0	111.3	G105 G106 G111 I112 C113	G105-L109 PolarHBondContact O-N 2.97Å; G106-L109 PolarHBondContact O-N 3.04Å; L109-G111 VanDerWaalsContact C-N 3.29Å; L109-G111 PolarHBondContact O-N 3.19Å; L109-I112 PolarHBondContact O-N 2.71Å; L109-C113 PolarHBondContact O-N 3.36Å; L109-C113 VanDerWaalsContact O-N 3.11Å; L109-C113 PolarHBondContact O-SG 2.99Å
110	F	91.8	Very high	88.6	Confident	2 Å²	2	42.2 Å²	42.2	1%	0.009	23%	0.226	C	C	.	.	H	α-helix	trans	-64.2	-37	178.5	-66.8	-59.2	0	0	0	111.5	G106 I112 C113 T114 F246 E249 Y250 F253 W508	G106-F110 WeakPolarHBondContact O-CD2 3.38Å; G106-F110 PolarHBondContact O-N 3.32Å; F110-I112 PolarHBondContact O-N 3.16Å; F110-C113 PolarHBondContact O-N 3.4Å; F110-T114 PolarHBondContact O-N 3.19Å; F110-T114 PolarHBondContact O-OG1 2.95Å; F110-F246 HydrophobicContact CD1-CB 4.33Å; F110-F246 AromaticContact CD1-CD1 3.82Å; F110-F246 HydrophobicContact CD1-CD1 3.82Å; F110-F246 AromaticContact CE1-CD1 3.9Å; F110-F246 HydrophobicContact CE1-CD1 3.9Å; F110-E249 HydrophobicContact CD1-CB 3.86Å; F110-E249 HydrophobicContact CD2-CB 4.34Å; F110-E249 HydrophobicContact CE1-CB 3.82Å; F110-E249 HydrophobicContact CE1-CG 4.1Å; F110-E249 HydrophobicContact CE2-CB 4.32Å; F110-E249 HydrophobicContact CG-CB 4.13Å; F110-E249 HydrophobicContact CZ-CB 4.05Å; F110-E249 HydrophobicContact CZ-CG 4.29Å; F110-Y250 HydrophobicContact CB-CD2 4.33Å; F110-F253 HydrophobicContact CD2-CD2 4.02Å; F110-F253 HydrophobicContact CD2-CE2 4.09Å; F110-F253 HydrophobicContact CD2-CG 4.42Å; F110-F253 AromaticContact CE2-CD2 3.9Å; F110-F253 HydrophobicContact CE2-CD2 3.9Å; F110-F253 AromaticContact CE2-CE2 3.49Å; F110-F253 HydrophobicContact CE2-CE2 3.49Å; F110-F253 VanDerWaalsContact CE2-CE2 3.49Å; F110-F253 AromaticContact CE2-CZ 3.87Å; F110-F253 HydrophobicContact CE2-CZ 3.87Å; F110-F253 HydrophobicContact CZ-CE2 4.31Å; F110-W508 HydrophobicContact CE1-CZ2 4.28Å; F110-W508 AromaticContact CZ-CZ2 3.79Å; F110-W508 HydrophobicContact CZ-CZ2 3.79Å
111	G	94.8	Very high	89.3	Confident	2 Å²	2	40.7 Å²	40.7	2%	0.021	22%	0.215	C	C	.	.	H	α-helix	trans	-59.3	-43.9	174.6	0	0	0	0	0	112.6	L107 V108 L109 T114 L115	L107-G111 PolarHBondContact O-N 3.28Å; V108-G111 PolarHBondContact O-N 3.06Å; L109-G111 VanDerWaalsContact C-N 3.29Å; L109-G111 PolarHBondContact O-N 3.19Å; G111-T114 PolarHBondContact O-N 3.49Å; G111-L115 VanDerWaalsContact O-CG 3.3Å; G111-L115 WeakPolarHBondContact O-CG 3.32Å; G111-L115 PolarHBondContact O-N 3.42Å
112	I	95.1	Very high	90	Very high	92 Å²	92	35.7 Å²	35.7	47%	0.472	19%	0.191	S	C	.	.	H	α-helix	trans	-63.3	-46	176.1	-68.5	165.2	0	0	0	110.7	V108 L109 F110 T114 L115 I116	V108-I112 HydrophobicContact CG1-CD1 3.84Å; V108-I112 HydrophobicContact CG1-CG1 4.42Å; V108-I112 VanDerWaalsContact O-CG1 3.3Å; V108-I112 WeakPolarHBondContact O-CG1 3.36Å; V108-I112 PolarHBondContact O-N 3.17Å; L109-I112 PolarHBondContact O-N 2.71Å; F110-I112 PolarHBondContact O-N 3.16Å; I112-T114 VanDerWaalsContact C-N 3.32Å; I112-T114 PolarHBondContact O-N 3.32Å; I112-L115 PolarHBondContact O-N 2.92Å; I112-I116 HydrophobicContact CG2-CD1 4.11Å; I112-I116 WeakPolarHBondContact O-CG1 3.25Å; I112-I116 PolarHBondContact O-N 3.34Å
113	C	92.8	Very high	90.7	Very high	23 Å²	23	32.7 Å²	32.7	16%	0.155	18%	0.183	C	C	.	.	H	α-helix	trans	-60.3	-40.6	176.8	-67.6	0	0	0	0	112.2	L109 F110 I116 M117 F246	L109-C113 PolarHBondContact O-N 3.36Å; L109-C113 VanDerWaalsContact O-N 3.11Å; L109-C113 PolarHBondContact O-SG 2.99Å; F110-C113 PolarHBondContact O-N 3.4Å; C113-I116 PolarHBondContact O-N 3.04Å; C113-M117 PolarHBondContact O-N 2.97Å; C113-F246 HydrophobicContact CB-CB 3.53Å; C113-F246 HydrophobicContact CB-CD1 4.32Å; C113-F246 HydrophobicContact CB-CD2 3.94Å; C113-F246 HydrophobicContact CB-CG 3.67Å
114	T	94.3	Very high	91.2	Very high	0 Å²	0	34.3 Å²	34.3	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-63.7	-40.4	174.3	-56.6	0	0	0	0	112.1	F110 G111 I112 I116 M117 D118 V147 N247	F110-T114 PolarHBondContact O-N 3.19Å; F110-T114 PolarHBondContact O-OG1 2.95Å; G111-T114 PolarHBondContact O-N 3.49Å; I112-T114 VanDerWaalsContact C-N 3.32Å; I112-T114 PolarHBondContact O-N 3.32Å; T114-I116 VanDerWaalsContact C-N 3.34Å; T114-I116 PolarHBondContact O-N 3.38Å; T114-M117 HydrophobicContact CG2-CE 4.21Å; T114-M117 CarbonylContact O-C 3.54Å; T114-M117 WeakPolarHBondContact O-CB 3.41Å; T114-M117 PolarHBondContact O-N 2.97Å; T114-D118 PolarHBondContact O-N 3.28Å; T114-V147 HydrophobicContact CG2-CG2 4.01Å; T114-N247 HydrophobicContact CG2-CB 3.96Å; T114-N247 WeakPolarHBondContact CG2-OD1 3.11Å; T114-N247 WeakPolarHBondContact OG1-CA 3.22Å
115	L	95.7	Very high	91.2	Very high	43 Å²	43	33.8 Å²	33.8	23%	0.225	19%	0.186	C	C	.	.	H	α-helix	trans	-64.6	-39.3	175.8	-68.8	173.8	0	0	0	112.1	G111 I112 M117 D118 I119 A144 V147 I148	G111-L115 VanDerWaalsContact O-CG 3.3Å; G111-L115 WeakPolarHBondContact O-CG 3.32Å; G111-L115 PolarHBondContact O-N 3.42Å; I112-L115 PolarHBondContact O-N 2.92Å; L115-M117 VanDerWaalsContact C-N 3.35Å; L115-D118 PolarHBondContact O-N 2.94Å; L115-I119 WeakPolarHBondContact O-CG1 3.36Å; L115-I119 PolarHBondContact O-N 3.47Å; L115-I119 VanDerWaalsContact O-N 3.11Å; L115-A144 HydrophobicContact CD2-CB 3.83Å; L115-A144 WeakPolarHBondContact CD2-O 3.02Å; L115-V147 HydrophobicContact CD2-CB 4.11Å; L115-V147 HydrophobicContact CD2-CG1 4.04Å; L115-V147 HydrophobicContact CG-CG1 4.09Å; L115-I148 HydrophobicContact CD1-CD1 4.42Å; L115-I148 HydrophobicContact CD1-CG1 3.81Å; L115-I148 HydrophobicContact CD2-CD1 4.17Å; L115-I148 HydrophobicContact CD2-CG1 3.85Å; L115-I148 HydrophobicContact CG-CG1 4.49Å
116	I	94.9	Very high	91	Very high	69 Å²	69	34.7 Å²	34.7	35%	0.354	19%	0.187	S	C	.	.	H	α-helix	trans	-61.4	-48.4	172.5	-62.7	167.9	0	0	0	108.9	I112 C113 T114 D118 I119 F120 L243	I112-I116 HydrophobicContact CG2-CD1 4.11Å; I112-I116 WeakPolarHBondContact O-CG1 3.25Å; I112-I116 PolarHBondContact O-N 3.34Å; C113-I116 PolarHBondContact O-N 3.04Å; T114-I116 VanDerWaalsContact C-N 3.34Å; T114-I116 PolarHBondContact O-N 3.38Å; I116-D118 VanDerWaalsContact C-N 3.29Å; I116-D118 PolarHBondContact O-N 3.05Å; I116-I119 WeakPolarHBondContact O-CB 3.29Å; I116-I119 PolarHBondContact O-N 3.33Å; I116-F120 HydrophobicContact CG2-CD2 3.75Å; I116-F120 HydrophobicContact CG2-CE2 3.59Å; I116-F120 VanDerWaalsContact O-CD2 3.3Å; I116-F120 WeakPolarHBondContact O-CD2 3.3Å; I116-F120 PolarHBondContact O-N 3.38Å; I116-L243 HydrophobicContact CB-CD1 4.12Å; I116-L243 HydrophobicContact CG2-CD1 3.53Å
117	M	92.8	Very high	90.8	Very high	0 Å²	0	37.1 Å²	37.1	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-54.4	-43.5	175.7	-174.1	-153.5	66.8	0	0	112.2	C113 T114 L115 I119 F120 K121 Y240 L243 Y244 N247	C113-M117 PolarHBondContact O-N 2.97Å; T114-M117 HydrophobicContact CG2-CE 4.21Å; T114-M117 CarbonylContact O-C 3.54Å; T114-M117 WeakPolarHBondContact O-CB 3.41Å; T114-M117 PolarHBondContact O-N 2.97Å; L115-M117 VanDerWaalsContact C-N 3.35Å; M117-I119 VanDerWaalsContact C-N 3.3Å; M117-I119 PolarHBondContact O-N 2.96Å; M117-F120 PolarHBondContact O-N 2.88Å; M117-F120 VanDerWaalsContact O-N 3.17Å; M117-K121 WeakPolarHBondContact O-CB 3.29Å; M117-K121 PolarHBondContact O-N 2.97Å; M117-Y240 HydrophobicContact CG-CD2 3.9Å; M117-Y240 HydrophobicContact CG-CE2 4.39Å; M117-Y240 HydrophobicContact SD-CD2 4.4Å; M117-Y240 HydrophobicContact SD-CE2 4.32Å; M117-L243 HydrophobicContact CB-CB 3.73Å; M117-L243 HydrophobicContact CB-CD1 4.34Å; M117-L243 HydrophobicContact CG-CB 3.98Å; M117-Y244 HydrophobicContact SD-CD2 4Å; M117-Y244 HydrophobicContact SD-CE2 4.49Å; M117-N247 HydrophobicContact CE-CB 3.82Å; M117-N247 HydrophobicContact SD-CB 3.71Å
118	D	93.8	Very high	90	Very high	2 Å²	2	38.1 Å²	38.1	1%	0.011	21%	0.207	C	C	.	.	H	α-helix	trans	-63.8	-34.3	178.5	-73.6	-27.8	0	0	0	112.4	T114 L115 I116 T122 Q143 A144	T114-D118 PolarHBondContact O-N 3.28Å; L115-D118 PolarHBondContact O-N 2.94Å; I116-D118 VanDerWaalsContact C-N 3.29Å; I116-D118 PolarHBondContact O-N 3.05Å; D118-T122 VanDerWaalsContact O-CB 3.3Å; D118-T122 WeakPolarHBondContact O-CB 3.5Å; D118-T122 PolarHBondContact O-N 3.4Å; D118-T122 PolarHBondContact O-OG1 3.36Å; D118-Q143 PolarHBondContact OD1-NE2 3.43Å; D118-Q143 PolarHBondContact OD2-NE2 3.49Å; D118-A144 HydrophobicContact CB-CB 4.07Å; D118-A144 PolarHBondContact OD2-N 3.43Å
119	I	93.2	Very high	89	Confident	114 Å²	114	42.3 Å²	42.3	59%	0.585	22%	0.222	S	C	*	.	H	α-helix	trans	-64.3	-48.3	171.7	-65.4	164.6	0	0	0	110.2	L115 I116 M117 K121 T122 G123	L115-I119 WeakPolarHBondContact O-CG1 3.36Å; L115-I119 PolarHBondContact O-N 3.47Å; L115-I119 VanDerWaalsContact O-N 3.11Å; I116-I119 WeakPolarHBondContact O-CB 3.29Å; I116-I119 PolarHBondContact O-N 3.33Å; M117-I119 VanDerWaalsContact C-N 3.3Å; M117-I119 PolarHBondContact O-N 2.96Å; I119-K121 PolarHBondContact O-N 3.35Å; I119-T122 PolarHBondContact O-N 2.88Å; I119-G123 PolarHBondContact O-N 3.41Å
120	F	92.3	Very high	88	Confident	58 Å²	58	45.8 Å²	45.8	25%	0.254	24%	0.236	S	C	.	.	H	α-helix	trans	-60.9	-43.9	177.3	-83.5	-94.9	0	0	0	111.7	I116 M117 T122 G123 Y124 F236 L243	I116-F120 HydrophobicContact CG2-CD2 3.75Å; I116-F120 HydrophobicContact CG2-CE2 3.59Å; I116-F120 VanDerWaalsContact O-CD2 3.3Å; I116-F120 WeakPolarHBondContact O-CD2 3.3Å; I116-F120 PolarHBondContact O-N 3.38Å; M117-F120 PolarHBondContact O-N 2.88Å; M117-F120 VanDerWaalsContact O-N 3.17Å; F120-T122 PolarHBondContact O-N 3.07Å; F120-G123 PolarHBondContact O-N 3.15Å; F120-Y124 PolarHBondContact O-N 3.02Å; F120-F236 HydrophobicContact CB-CD1 4.45Å; F120-F236 AromaticContact CD1-CD1 3.76Å; F120-F236 HydrophobicContact CD1-CD1 3.76Å; F120-F236 HydrophobicContact CD1-CE1 4.48Å; F120-F236 HydrophobicContact CE1-CD1 4.31Å; F120-F236 HydrophobicContact CG-CD1 4.3Å; F120-L243 HydrophobicContact CD2-CD1 4.08Å; F120-L243 HydrophobicContact CE2-CD1 4.35Å
121	K	90.1	Very high	87.1	Confident	10 Å²	10	47.8 Å²	47.8	4%	0.043	25%	0.249	C	C	.	.	H	α-helix	trans	-63.2	-41.4	177.6	-170.5	170.1	-171.6	152.3	0	111.9	M117 I119 Y124 Y125 P140 Y240	M117-K121 WeakPolarHBondContact O-CB 3.29Å; M117-K121 PolarHBondContact O-N 2.97Å; I119-K121 PolarHBondContact O-N 3.35Å; K121-Y124 PolarHBondContact O-N 3.01Å; K121-Y125 HydrophobicContact CD-CE2 4.05Å; K121-Y125 VanDerWaalsContact CE-CE2 3.42Å; K121-Y125 WeakPolarHBondContact CE-OH 3.27Å; K121-Y125 HydrophobicContact CG-CD2 3.9Å; K121-Y125 HydrophobicContact CG-CE2 3.5Å; K121-Y125 WeakPolarHBondContact O-CD2 3.32Å; K121-Y125 PolarHBondContact O-N 2.95Å; K121-P140 HydrophobicContact CB-CB 4.34Å; K121-P140 HydrophobicContact CD-CB 4.23Å; K121-P140 HydrophobicContact CG-CB 4.21Å; K121-P140 HydrophobicContact CG-CG 4.48Å; K121-Y240 HydrophobicContact CB-CD2 3.86Å; K121-Y240 HydrophobicContact CB-CE2 4.17Å; K121-Y240 HydrophobicContact CB-CG 4.47Å; K121-Y240 HydrophobicContact CD-CD2 4.13Å; K121-Y240 HydrophobicContact CD-CE2 3.53Å; K121-Y240 WeakPolarHBondContact CE-OH 3.21Å; K121-Y240 HydrophobicContact CG-CD2 4.1Å; K121-Y240 HydrophobicContact CG-CE2 3.94Å; K121-Y240 PolarHBondContact NZ-OH 3.23Å
122	T	90.3	Very high	86.1	Confident	36 Å²	36	51.1 Å²	51.1	22%	0.221	27%	0.265	C	S	.	.	H	α-helix	trans	-65.3	-42.5	174.9	-55.6	0	0	0	0	111.2	D118 I119 F120 Y124 Y125 S126 V141	D118-T122 VanDerWaalsContact O-CB 3.3Å; D118-T122 WeakPolarHBondContact O-CB 3.5Å; D118-T122 PolarHBondContact O-N 3.4Å; D118-T122 PolarHBondContact O-OG1 3.36Å; I119-T122 PolarHBondContact O-N 2.88Å; F120-T122 PolarHBondContact O-N 3.07Å; T122-Y124 PolarHBondContact O-N 2.85Å; T122-Y125 PolarHBondContact O-N 3.13Å; T122-S126 VanDerWaalsContact O-CB 3.23Å; T122-S126 WeakPolarHBondContact O-CB 3.48Å; T122-S126 PolarHBondContact O-N 3.22Å; T122-S126 PolarHBondContact O-OG 3.45Å; T122-V141 HydrophobicContact CG2-CG2 4.22Å
123	G	88.3	Confident	85.4	Confident	9 Å²	9	49.7 Å²	49.7	9%	0.093	26%	0.262	C	S	.	.	H	α-helix	trans	-60.7	-42	174.3	0	0	0	0	0	112.9	I119 F120 S126 S127	I119-G123 PolarHBondContact O-N 3.41Å; F120-G123 PolarHBondContact O-N 3.15Å; G123-S126 WeakPolarHBondContact CA-OG 3.27Å; G123-S126 PolarHBondContact O-OG 3.44Å; G123-S127 PolarHBondContact O-N 3.09Å; G123-S127 PolarHBondContact O-OG 3.26Å
124	Y	86.9	Confident	85	Confident	49 Å²	49	52.2 Å²	52.2	19%	0.192	29%	0.285	C	S	.	.	H	α-helix	trans	-62.2	-53	175.4	178.1	-109.2	0	0	0	111.9	F120 K121 T122 S127 F128 Q237	F120-Y124 PolarHBondContact O-N 3.02Å; K121-Y124 PolarHBondContact O-N 3.01Å; T122-Y124 PolarHBondContact O-N 2.85Å; Y124-S127 WeakPolarHBondContact O-CB 3.4Å; Y124-S127 PolarHBondContact O-N 3.42Å; Y124-F128 HydrophobicContact CD2-CE2 4.19Å; Y124-F128 AromaticContact CE2-CE2 3.78Å; Y124-F128 HydrophobicContact CE2-CE2 3.78Å; Y124-F128 VanDerWaalsContact O-CD2 3.27Å; Y124-F128 WeakPolarHBondContact O-CD2 3.34Å; Y124-Q237 HydrophobicContact CD2-CB 3.83Å; Y124-Q237 HydrophobicContact CD2-CG 4.36Å; Y124-Q237 HydrophobicContact CE2-CB 3.83Å; Y124-Q237 HydrophobicContact CE2-CG 3.95Å
125	Y	84.4	Confident	84.5	Confident	22 Å²	22	53.9 Å²	53.9	9%	0.086	29%	0.294	C	S	.	.	H	α-helix	trans	-71.5	-31.7	-178.4	-66.6	-46.3	0	0	0	114	K121 T122 S127 F128 K136 P140	K121-Y125 HydrophobicContact CD-CE2 4.05Å; K121-Y125 VanDerWaalsContact CE-CE2 3.42Å; K121-Y125 WeakPolarHBondContact CE-OH 3.27Å; K121-Y125 HydrophobicContact CG-CD2 3.9Å; K121-Y125 HydrophobicContact CG-CE2 3.5Å; K121-Y125 WeakPolarHBondContact O-CD2 3.32Å; K121-Y125 PolarHBondContact O-N 2.95Å; T122-Y125 PolarHBondContact O-N 3.13Å; Y125-S127 PolarHBondContact O-N 2.85Å; Y125-F128 PolarHBondContact O-N 3.46Å; Y125-F128 VanDerWaalsContact O-N 3.1Å; Y125-K136 WeakPolarHBondContact CD2-O 3.39Å; Y125-P140 HydrophobicContact CD2-CG 4.43Å
126	S	83.3	Confident	83.9	Confident	55 Å²	55	53.3 Å²	53.3	39%	0.385	29%	0.289	S	S	.	.	H	α-helix	trans	-67	-25.5	175.1	57.6	0	0	0	0	112.7	T122 G123 F128 F129	T122-S126 VanDerWaalsContact O-CB 3.23Å; T122-S126 WeakPolarHBondContact O-CB 3.48Å; T122-S126 PolarHBondContact O-N 3.22Å; T122-S126 PolarHBondContact O-OG 3.45Å; G123-S126 WeakPolarHBondContact CA-OG 3.27Å; G123-S126 PolarHBondContact O-OG 3.44Å; S126-F128 PolarHBondContact O-N 2.87Å; S126-F128 VanDerWaalsContact O-N 3.16Å; S126-F129 PolarHBondContact O-N 2.96Å
127	S	80.1	Confident	83.5	Confident	58 Å²	58	52.2 Å²	52.2	41%	0.406	28%	0.284	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.2	-13	172.4	-58.3	0	0	0	0	113.2	G123 Y124 Y125	G123-S127 PolarHBondContact O-N 3.09Å; G123-S127 PolarHBondContact O-OG 3.26Å; Y124-S127 WeakPolarHBondContact O-CB 3.4Å; Y124-S127 PolarHBondContact O-N 3.42Å; Y125-S127 PolarHBondContact O-N 2.85Å
128	F	72.9	Confident	83.3	Confident	21 Å²	21	56.5 Å²	56.5	9%	0.092	31%	0.306	C	S	.	.	T	Hydrogen-bonded Turn	trans	-123.5	31.2	179.2	-59.2	-77.4	0	0	0	113.1	Y124 Y125 S126 E130 C131 Q132 C228 C233	Y124-F128 HydrophobicContact CD2-CE2 4.19Å; Y124-F128 AromaticContact CE2-CE2 3.78Å; Y124-F128 HydrophobicContact CE2-CE2 3.78Å; Y124-F128 VanDerWaalsContact O-CD2 3.27Å; Y124-F128 WeakPolarHBondContact O-CD2 3.34Å; Y125-F128 PolarHBondContact O-N 3.46Å; Y125-F128 VanDerWaalsContact O-N 3.1Å; S126-F128 PolarHBondContact O-N 2.87Å; S126-F128 VanDerWaalsContact O-N 3.16Å; F128-E130 PolarHBondContact O-N 3.44Å; F128-E130 VanDerWaalsContact O-N 3.1Å; F128-C131 HydrophobicContact CB-CB 4.36Å; F128-C131 PolarHBondContact O-N 3.07Å; F128-Q132 HydrophobicContact CB-CG 3.94Å; F128-Q132 PolarHBondContact O-N 2.67Å; F128-C228 HydrophobicContact CE1-CB 4.47Å; F128-C228 HydrophobicContact CE2-CB 4.48Å; F128-C228 HydrophobicContact CZ-CB 3.62Å; F128-C233 WeakPolarHBondContact CE2-SG 3.17Å; F128-C233 WeakPolarHBondContact CZ-SG 3.46Å
129	F	70.6	Confident	83.2	Confident	136 Å²	136	56.6 Å²	56.6	60%	0.596	31%	0.306	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.8	-29.9	-171.2	83.9	-87.6	0	0	0	114	S126 I137	S126-F129 PolarHBondContact O-N 2.96Å; F129-I137 HydrophobicContact CB-CD1 4.19Å
130	E	69.9	Low	83.2	Confident	160 Å²	160	51.1 Å²	51.1	75%	0.748	28%	0.279	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.6	-19.9	176.2	-61.2	-165.4	165	0	0	113.5	F128	F128-E130 PolarHBondContact O-N 3.44Å; F128-E130 VanDerWaalsContact O-N 3.1Å
131	C	73.1	Confident	83.3	Confident	44 Å²	44	51.6 Å²	51.6	30%	0.297	29%	0.286	S	S	.	.	T	Hydrogen-bonded Turn	trans	-105.9	-5.2	-173.2	-58.4	0	0	0	0	113.9	F128 C226	F128-C131 HydrophobicContact CB-CB 4.36Å; F128-C131 PolarHBondContact O-N 3.07Å; C131-C226 HydrophobicContact CB-CB 3.85Å; C131-C226 WeakPolarHBondContact CB-SG 3.4Å; C131-C226 WeakPolarHBondContact SG-CB 3.43Å; C131-C226 CovalentContact SG-SG 2.04Å; C131-C226 PolarHBondContact SG-SG 3.17Å
132	Q	73.2	Confident	83.6	Confident	73 Å²	73	52.2 Å²	52.2	34%	0.341	29%	0.289	S	S	.	.	S	Bend	trans	-129.2	150.7	-172.6	-65.9	-67.1	-18.3	0	0	112.3	F128	F128-Q132 HydrophobicContact CB-CG 3.94Å; F128-Q132 PolarHBondContact O-N 2.67Å
133	S	80	Confident	83.9	Confident	61 Å²	61	50.7 Å²	50.7	43%	0.427	28%	0.28	S	S	.	.			trans	-66.9	141.6	174.4	-179.2	0	0	0	0	111.4	I135 K136	S133-I135 PolarHBondContact O-N 2.81Å; S133-K136 PolarHBondContact O-N 3.38Å
134	A	84.1	Confident	84.3	Confident	76 Å²	76	51.4 Å²	51.4	63%	0.628	29%	0.285	S	S	*	.	H	α-helix	trans	-54.2	-28.9	-179.3	0	0	0	0	0	113.5	K136 I137 L138	A134-K136 VanDerWaalsContact C-N 3.26Å; A134-K136 PolarHBondContact O-N 3.41Å; A134-I137 PolarHBondContact O-N 3.49Å; A134-I137 VanDerWaalsContact O-N 3.17Å; A134-L138 WeakPolarHBondContact O-CB 3.36Å; A134-L138 PolarHBondContact O-N 3.47Å
135	I	84.8	Confident	84.8	Confident	36 Å²	36	52.2 Å²	52.2	19%	0.185	30%	0.295	C	S	.	.	H	α-helix	trans	-61.2	-32.6	178.5	-167.4	61.1	0	0	0	112.7	T60 F63 S133 I137 L138 H139	T60-I135 HydrophobicContact CG2-CG2 3.84Å; F63-I135 HydrophobicContact CB-CG1 4.09Å; S133-I135 PolarHBondContact O-N 2.81Å; I135-I137 VanDerWaalsContact C-N 3.31Å; I135-I137 PolarHBondContact O-N 3.04Å; I135-L138 PolarHBondContact O-N 3.5Å; I135-H139 VanDerWaalsContact O-CB 3.3Å; I135-H139 WeakPolarHBondContact O-CB 3.32Å; I135-H139 PolarHBondContact O-N 3.44Å
136	K	83.4	Confident	85.5	Confident	30 Å²	30	51.2 Å²	51.2	13%	0.13	29%	0.291	C	S	.	.	H	α-helix	trans	-69.9	-29.3	178.8	-70.2	-173.1	177.4	-177.2	0	112.5	D59 F63 Y125 S133 A134 P140	D59-K136 IonicContact OD2-NZ 3.88Å; F63-K136 HydrophobicContact CD2-CG 4Å; F63-K136 HydrophobicContact CE2-CD 4.45Å; F63-K136 HydrophobicContact CE2-CG 4.02Å; Y125-K136 WeakPolarHBondContact CD2-O 3.39Å; S133-K136 PolarHBondContact O-N 3.38Å; A134-K136 VanDerWaalsContact C-N 3.26Å; A134-K136 PolarHBondContact O-N 3.41Å; K136-P140 WeakPolarHBondContact O-CD 3.27Å
137	I	85.9	Confident	86.1	Confident	46 Å²	46	48.7 Å²	48.7	24%	0.236	27%	0.273	C	S	.	.	H	α-helix	trans	-81.8	-40.1	175.5	-60.6	171.7	0	0	0	110.4	F129 A134 I135 P140	F129-I137 HydrophobicContact CB-CD1 4.19Å; A134-I137 PolarHBondContact O-N 3.49Å; A134-I137 VanDerWaalsContact O-N 3.17Å; I135-I137 VanDerWaalsContact C-N 3.31Å; I135-I137 PolarHBondContact O-N 3.04Å; I137-P140 VanDerWaalsContact O-CD 3.31Å; I137-P140 WeakPolarHBondContact O-CD 3.33Å; I137-P140 WeakPolarHBondContact O-CG 3.36Å
138	L	89.3	Confident	87	Confident	91 Å²	91	50.6 Å²	50.6	48%	0.476	28%	0.278	S	S	.	.	H	α-helix	trans	-70.9	-36.1	-177.6	-171.3	60	0	0	0	112.8	A134 I135 V141 I142	A134-L138 WeakPolarHBondContact O-CB 3.36Å; A134-L138 PolarHBondContact O-N 3.47Å; I135-L138 PolarHBondContact O-N 3.5Å; L138-V141 PolarHBondContact O-N 3.29Å; L138-I142 HydrophobicContact CD1-CD1 4.13Å; L138-I142 HydrophobicContact CD1-CG1 4.28Å; L138-I142 HydrophobicContact CD2-CD1 4Å; L138-I142 HydrophobicContact CG-CD1 3.63Å; L138-I142 HydrophobicContact CG-CG1 4.18Å; L138-I142 WeakPolarHBondContact O-CG1 3.41Å; L138-I142 PolarHBondContact O-N 3.36Å
139	H	91.4	Very high	88.1	Confident	3 Å²	3	51.1 Å²	51.1	1%	0.014	28%	0.281	C	S	.	.	H	α-helix	trans	-53.7	-56.4	-179.1	176.9	-80.9	0	0	0	114.1	F63 T67 I135 V141 I142 Q143	F63-H139 HydrophobicContact CB-CB 4.49Å; F63-H139 HydrophobicContact CD1-CB 4Å; F63-H139 AromaticContact CD1-CD2 3.55Å; F63-H139 AromaticContact CD1-CE1 4Å; F63-H139 AromaticContact CD1-CG 3.5Å; F63-H139 AromaticContact CD1-ND1 3.79Å; F63-H139 AromaticContact CD1-NE2 3.86Å; T67-H139 PolarHBondContact OG1-CD2 2.93Å; I135-H139 VanDerWaalsContact O-CB 3.3Å; I135-H139 WeakPolarHBondContact O-CB 3.32Å; I135-H139 PolarHBondContact O-N 3.44Å; H139-V141 VanDerWaalsContact C-N 3.26Å; H139-V141 PolarHBondContact O-N 2.96Å; H139-I142 PolarHBondContact O-N 2.81Å; H139-Q143 PolarHBondContact CE1-OE1 2.91Å; H139-Q143 WeakPolarHBondContact O-CB 3.22Å; H139-Q143 PolarHBondContact O-N 3.08Å
140	P	93.2	Very high	89.4	Confident	0 Å²	0	44.7 Å²	44.7	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-62.4	-31.3	-180	24.7	-34.9	0	0	0	113	K121 Y125 K136 I137 Q143 A144	K121-P140 HydrophobicContact CB-CB 4.34Å; K121-P140 HydrophobicContact CD-CB 4.23Å; K121-P140 HydrophobicContact CG-CB 4.21Å; K121-P140 HydrophobicContact CG-CG 4.48Å; Y125-P140 HydrophobicContact CD2-CG 4.43Å; K136-P140 WeakPolarHBondContact O-CD 3.27Å; I137-P140 VanDerWaalsContact O-CD 3.31Å; I137-P140 WeakPolarHBondContact O-CD 3.33Å; I137-P140 WeakPolarHBondContact O-CG 3.36Å; P140-Q143 PolarHBondContact O-N 3.5Å; P140-A144 WeakPolarHBondContact O-CB 3.33Å; P140-A144 PolarHBondContact O-N 2.9Å
141	V	94.7	Very high	90.6	Very high	67 Å²	67	38 Å²	38	41%	0.406	22%	0.223	S	C	.	.	H	α-helix	trans	-66.1	-45.2	174.8	178.3	0	0	0	0	110.9	T122 L138 H139 Q143 A144 V145	T122-V141 HydrophobicContact CG2-CG2 4.22Å; L138-V141 PolarHBondContact O-N 3.29Å; H139-V141 VanDerWaalsContact C-N 3.26Å; H139-V141 PolarHBondContact O-N 2.96Å; V141-Q143 VanDerWaalsContact C-N 3.33Å; V141-A144 PolarHBondContact O-N 3.03Å; V141-V145 WeakPolarHBondContact O-CG2 3.15Å; V141-V145 PolarHBondContact O-N 2.69Å
142	I	96.1	Very high	91.7	Very high	23 Å²	23	42.5 Å²	42.5	12%	0.118	24%	0.235	C	C	.	.	H	α-helix	trans	-65.8	-39.4	176.5	-68.1	174.4	0	0	0	110.8	T67 M70 L71 M74 L138 H139 A144 V145 F146	T67-I142 HydrophobicContact CG2-CD1 3.36Å; T67-I142 HydrophobicContact CG2-CG2 4.27Å; M70-I142 HydrophobicContact CB-CG2 4.28Å; M70-I142 HydrophobicContact CE-CG2 4.29Å; L71-I142 HydrophobicContact CD2-CD1 4.45Å; L71-I142 HydrophobicContact CD2-CG2 4.07Å; L71-I142 HydrophobicContact CG-CG2 4.22Å; M74-I142 HydrophobicContact CE-CG2 4.03Å; L138-I142 HydrophobicContact CD1-CD1 4.13Å; L138-I142 HydrophobicContact CD1-CG1 4.28Å; L138-I142 HydrophobicContact CD2-CD1 4Å; L138-I142 HydrophobicContact CG-CD1 3.63Å; L138-I142 HydrophobicContact CG-CG1 4.18Å; L138-I142 WeakPolarHBondContact O-CG1 3.41Å; L138-I142 PolarHBondContact O-N 3.36Å; H139-I142 PolarHBondContact O-N 2.81Å; I142-A144 PolarHBondContact O-N 3.38Å; I142-V145 PolarHBondContact O-N 3.08Å; I142-F146 WeakPolarHBondContact O-CB 3.42Å; I142-F146 PolarHBondContact O-N 3.18Å
143	Q	96.3	Very high	92.7	Very high	5 Å²	5	39 Å²	39	2%	0.023	22%	0.219	C	C	.	.	H	α-helix	trans	-59.4	-45.3	174.9	-171.3	-179.8	-64.2	0	0	111.4	M70 D118 H139 P140 V141 V145 F146 V147	M70-Q143 HydrophobicContact CE-CB 4.17Å; M70-Q143 HydrophobicContact SD-CB 3.89Å; M70-Q143 HydrophobicContact SD-CG 4Å; D118-Q143 PolarHBondContact OD1-NE2 3.43Å; D118-Q143 PolarHBondContact OD2-NE2 3.49Å; H139-Q143 PolarHBondContact CE1-OE1 2.91Å; H139-Q143 WeakPolarHBondContact O-CB 3.22Å; H139-Q143 PolarHBondContact O-N 3.08Å; P140-Q143 PolarHBondContact O-N 3.5Å; V141-Q143 VanDerWaalsContact C-N 3.33Å; Q143-V145 VanDerWaalsContact C-N 3.33Å; Q143-V145 PolarHBondContact O-N 2.94Å; Q143-F146 WeakPolarHBondContact O-CB 3.35Å; Q143-F146 PolarHBondContact O-N 2.98Å; Q143-F146 VanDerWaalsContact O-N 3.13Å; Q143-V147 HydrophobicContact CG-CG2 4.4Å; Q143-V147 WeakPolarHBondContact O-CG2 3.03Å; Q143-V147 PolarHBondContact O-N 3.14Å
144	A	96.8	Very high	93.4	Very high	23 Å²	23	36.1 Å²	36.1	19%	0.19	20%	0.198	C	C	.	.	H	α-helix	trans	-59.2	-44.3	177.3	0	0	0	0	0	112	L115 D118 P140 V141 I142 F146 V147 I148	L115-A144 HydrophobicContact CD2-CB 3.83Å; L115-A144 WeakPolarHBondContact CD2-O 3.02Å; D118-A144 HydrophobicContact CB-CB 4.07Å; D118-A144 PolarHBondContact OD2-N 3.43Å; P140-A144 WeakPolarHBondContact O-CB 3.33Å; P140-A144 PolarHBondContact O-N 2.9Å; V141-A144 PolarHBondContact O-N 3.03Å; I142-A144 PolarHBondContact O-N 3.38Å; A144-F146 PolarHBondContact O-N 3.37Å; A144-V147 PolarHBondContact O-N 3.19Å; A144-I148 WeakPolarHBondContact O-CD1 3.31Å; A144-I148 VanDerWaalsContact O-CG1 3.29Å; A144-I148 WeakPolarHBondContact O-CG1 3.32Å; A144-I148 PolarHBondContact O-N 3.45Å
145	V	97.7	Very high	93.7	Very high	67 Å²	67	38.2 Å²	38.2	41%	0.406	19%	0.19	S	C	.	.	H	α-helix	trans	-63.8	-41.7	176	-180	0	0	0	0	111.2	M74 V141 I142 Q143 I148 I149	M74-V145 HydrophobicContact CE-CG1 4.46Å; M74-V145 HydrophobicContact SD-CB 4.27Å; M74-V145 HydrophobicContact SD-CG1 3.75Å; V141-V145 WeakPolarHBondContact O-CG2 3.15Å; V141-V145 PolarHBondContact O-N 2.69Å; I142-V145 PolarHBondContact O-N 3.08Å; Q143-V145 VanDerWaalsContact C-N 3.33Å; Q143-V145 PolarHBondContact O-N 2.94Å; V145-I148 PolarHBondContact O-N 3.31Å; V145-I149 HydrophobicContact CG1-CD1 3.83Å; V145-I149 HydrophobicContact CG1-CG1 4.45Å; V145-I149 WeakPolarHBondContact O-CG1 3.49Å; V145-I149 PolarHBondContact O-N 3.41Å
146	F	98	Very high	93.9	Very high	1 Å²	1	39.1 Å²	39.1	0%	0.004	20%	0.197	C	C	.	.	H	α-helix	trans	-60.3	-48.8	176.3	170.9	-110	0	0	0	111.9	M70 A73 M74 I77 I142 Q143 A144 I148 I149 Q150 T176 T179 I183	M70-F146 HydrophobicContact CB-CB 4.22Å; M70-F146 HydrophobicContact CB-CD2 4.31Å; M70-F146 HydrophobicContact CB-CG 4.12Å; M70-F146 HydrophobicContact CG-CB 4.33Å; M70-F146 HydrophobicContact CG-CD1 3.92Å; M70-F146 HydrophobicContact CG-CD2 4.42Å; M70-F146 HydrophobicContact CG-CE1 4.31Å; M70-F146 HydrophobicContact CG-CG 3.97Å; M70-F146 HydrophobicContact SD-CB 4.17Å; M70-F146 HydrophobicContact SD-CD1 3.95Å; M70-F146 HydrophobicContact SD-CG 4.22Å; A73-F146 HydrophobicContact CB-CE2 3.77Å; M74-F146 HydrophobicContact CG-CB 4.07Å; M74-F146 HydrophobicContact CG-CD2 3.66Å; M74-F146 HydrophobicContact CG-CG 4.37Å; M74-F146 WeakPolarHBondContact SD-CA 3.27Å; M74-F146 HydrophobicContact SD-CB 3.89Å; I77-F146 HydrophobicContact CD1-CE2 4.46Å; I142-F146 WeakPolarHBondContact O-CB 3.42Å; I142-F146 PolarHBondContact O-N 3.18Å; Q143-F146 WeakPolarHBondContact O-CB 3.35Å; Q143-F146 PolarHBondContact O-N 2.98Å; Q143-F146 VanDerWaalsContact O-N 3.13Å; A144-F146 PolarHBondContact O-N 3.37Å; F146-I148 VanDerWaalsContact C-N 3.33Å; F146-I148 PolarHBondContact O-N 3.38Å; F146-I149 PolarHBondContact O-N 3.28Å; F146-Q150 HydrophobicContact CE2-CB 4.44Å; F146-Q150 WeakPolarHBondContact O-CB 3.4Å; F146-Q150 PolarHBondContact O-N 3.16Å; F146-T176 HydrophobicContact CE2-CG2 4.46Å; F146-T176 HydrophobicContact CZ-CG2 4.44Å; F146-T179 HydrophobicContact CZ-CG2 4.2Å; F146-I183 HydrophobicContact CD1-CD1 4.17Å; F146-I183 HydrophobicContact CE1-CD1 3.74Å
147	V	97.3	Very high	94.2	Very high	2 Å²	2	37.7 Å²	37.7	1%	0.012	19%	0.191	C	C	.	.	H	α-helix	trans	-59.7	-42	177.8	170.6	0	0	0	0	111	T114 L115 Q143 A144 T151 Y250	T114-V147 HydrophobicContact CG2-CG2 4.01Å; L115-V147 HydrophobicContact CD2-CB 4.11Å; L115-V147 HydrophobicContact CD2-CG1 4.04Å; L115-V147 HydrophobicContact CG-CG1 4.09Å; Q143-V147 HydrophobicContact CG-CG2 4.4Å; Q143-V147 WeakPolarHBondContact O-CG2 3.03Å; Q143-V147 PolarHBondContact O-N 3.14Å; A144-V147 PolarHBondContact O-N 3.19Å; V147-T151 WeakPolarHBondContact O-CB 3.38Å; V147-T151 PolarHBondContact O-N 2.83Å; V147-T151 PolarHBondContact O-OG1 2.93Å; V147-Y250 HydrophobicContact CB-CE1 4.46Å; V147-Y250 HydrophobicContact CG1-CE1 4.18Å; V147-Y250 HydrophobicContact CG1-CE2 4.18Å; V147-Y250 HydrophobicContact CG2-CD1 4.4Å; V147-Y250 HydrophobicContact CG2-CE1 3.94Å; V147-Y250 PolarHBondContact O-OH 3.42Å
148	I	97.4	Very high	94.1	Very high	97 Å²	97	35.7 Å²	35.7	50%	0.497	18%	0.181	S	C	.	.	H	α-helix	trans	-61.6	-53.1	177	-69.4	163.6	0	0	0	110.9	L115 A144 V145 F146 Q150 T151 Y152	L115-I148 HydrophobicContact CD1-CD1 4.42Å; L115-I148 HydrophobicContact CD1-CG1 3.81Å; L115-I148 HydrophobicContact CD2-CD1 4.17Å; L115-I148 HydrophobicContact CD2-CG1 3.85Å; L115-I148 HydrophobicContact CG-CG1 4.49Å; A144-I148 WeakPolarHBondContact O-CD1 3.31Å; A144-I148 VanDerWaalsContact O-CG1 3.29Å; A144-I148 WeakPolarHBondContact O-CG1 3.32Å; A144-I148 PolarHBondContact O-N 3.45Å; V145-I148 PolarHBondContact O-N 3.31Å; F146-I148 VanDerWaalsContact C-N 3.33Å; F146-I148 PolarHBondContact O-N 3.38Å; I148-Q150 PolarHBondContact O-N 2.88Å; I148-T151 PolarHBondContact O-N 3.39Å; I148-Y152 WeakPolarHBondContact O-CB 3.4Å; I148-Y152 PolarHBondContact O-N 3.47Å
149	I	97.3	Very high	93.9	Very high	33 Å²	33	34.2 Å²	34.2	17%	0.169	17%	0.171	C	C	.	.	H	α-helix	trans	-64.2	-44	-176.8	-69.3	176.3	0	0	0	110.8	M74 I77 L78 V145 F146 Y152 F153	M74-I149 HydrophobicContact CG-CD1 4.38Å; M74-I149 HydrophobicContact SD-CD1 3.79Å; I77-I149 HydrophobicContact CB-CG2 4.24Å; I77-I149 HydrophobicContact CG2-CG2 3.67Å; L78-I149 HydrophobicContact CD1-CD1 4.43Å; L78-I149 HydrophobicContact CD2-CD1 4.4Å; L78-I149 HydrophobicContact CD2-CG2 4.43Å; V145-I149 HydrophobicContact CG1-CD1 3.83Å; V145-I149 HydrophobicContact CG1-CG1 4.45Å; V145-I149 WeakPolarHBondContact O-CG1 3.49Å; V145-I149 PolarHBondContact O-N 3.41Å; F146-I149 PolarHBondContact O-N 3.28Å; I149-Y152 PolarHBondContact O-N 3.26Å; I149-F153 WeakPolarHBondContact O-CB 3.31Å; I149-F153 PolarHBondContact O-N 3.31Å
150	Q	97.6	Very high	93.5	Very high	0 Å²	0	34.4 Å²	34.4	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-66.8	-43.3	179.8	-175.9	-176	7.5	0	0	112	I77 F146 I148 Y152 F153 L154 N180	I77-Q150 HydrophobicContact CD1-CB 4.25Å; I77-Q150 HydrophobicContact CD1-CG 4.44Å; F146-Q150 HydrophobicContact CE2-CB 4.44Å; F146-Q150 WeakPolarHBondContact O-CB 3.4Å; F146-Q150 PolarHBondContact O-N 3.16Å; I148-Q150 PolarHBondContact O-N 2.88Å; Q150-Y152 VanDerWaalsContact C-N 3.32Å; Q150-Y152 PolarHBondContact O-N 2.97Å; Q150-F153 WeakPolarHBondContact O-CB 3.41Å; Q150-F153 PolarHBondContact O-N 2.65Å; Q150-L154 HydrophobicContact CG-CD1 4.06Å; Q150-L154 HydrophobicContact CG-CG 4.36Å; Q150-L154 WeakPolarHBondContact O-CB 3.39Å; Q150-L154 WeakPolarHBondContact O-CG 3.36Å; Q150-L154 PolarHBondContact O-N 2.94Å; Q150-N180 VanDerWaalsContact NE2-CG 3.28Å; Q150-N180 PolarHBondContact NE2-ND2 3.06Å; Q150-N180 PolarHBondContact NE2-OD1 2.88Å; Q150-N180 PolarHBondContact OE1-OD1 2.9Å
151	T	96	Very high	92.9	Very high	20 Å²	20	34.4 Å²	34.4	12%	0.123	17%	0.172	C	C	.	.	H	α-helix	trans	-61.6	-44	178	-58.3	0	0	0	0	110.6	L107 V108 V147 I148 L154 W155 Y250	L107-T151 HydrophobicContact CD2-CG2 4.28Å; L107-T151 HydrophobicContact CG-CG2 4.36Å; V108-T151 HydrophobicContact CG2-CG2 4.01Å; V147-T151 WeakPolarHBondContact O-CB 3.38Å; V147-T151 PolarHBondContact O-N 2.83Å; V147-T151 PolarHBondContact O-OG1 2.93Å; I148-T151 PolarHBondContact O-N 3.39Å; T151-L154 PolarHBondContact O-N 3.47Å; T151-W155 VanDerWaalsContact O-CB 3.22Å; T151-W155 WeakPolarHBondContact O-CB 3.15Å; T151-W155 PolarHBondContact O-N 2.91Å; T151-Y250 PolarHBondContact N-OH 3.32Å; T151-Y250 WeakPolarHBondContact OG1-CE2 3.36Å; T151-Y250 PolarHBondContact OG1-OH 3.17Å
152	Y	94.9	Very high	92.4	Very high	139 Å²	139	31.3 Å²	31.3	55%	0.545	15%	0.153	S	C	.	.	H	α-helix	trans	-60	-47.3	174.1	176.8	-98.9	0	0	0	112	L81 I148 I149 Q150 L154 W155 V156	L81-Y152 HydrophobicContact CD1-CD1 3.85Å; L81-Y152 HydrophobicContact CD1-CE1 3.99Å; L81-Y152 HydrophobicContact CD2-CE1 4.36Å; I148-Y152 WeakPolarHBondContact O-CB 3.4Å; I148-Y152 PolarHBondContact O-N 3.47Å; I149-Y152 PolarHBondContact O-N 3.26Å; Q150-Y152 VanDerWaalsContact C-N 3.32Å; Q150-Y152 PolarHBondContact O-N 2.97Å; Y152-L154 PolarHBondContact O-N 3.2Å; Y152-W155 PolarHBondContact O-N 3.32Å; Y152-V156 HydrophobicContact CD2-CG2 4.34Å; Y152-V156 HydrophobicContact CE1-CG2 4.34Å; Y152-V156 HydrophobicContact CE2-CG2 3.92Å; Y152-V156 WeakPolarHBondContact O-CG2 3.34Å; Y152-V156 PolarHBondContact O-N 2.92Å
153	F	95.3	Very high	91.7	Very high	0 Å²	0	32.2 Å²	32.2	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-57.6	-50.9	177.9	164.5	-113.3	0	0	0	112.3	W76 I77 Y80 L81 I149 Q150 W155 V156 S157 L173 L258 M261	W76-F153 HydrophobicContact CH2-CZ 4.06Å; W76-F153 HydrophobicContact CZ3-CE1 4.28Å; W76-F153 HydrophobicContact CZ3-CZ 4.11Å; I77-F153 HydrophobicContact CD1-CD1 4.44Å; I77-F153 HydrophobicContact CG1-CD1 4.25Å; I77-F153 HydrophobicContact CG1-CG 4.48Å; I77-F153 HydrophobicContact CG2-CB 3.51Å; I77-F153 HydrophobicContact CG2-CD1 4.29Å; I77-F153 HydrophobicContact CG2-CD2 4.11Å; I77-F153 HydrophobicContact CG2-CG 3.71Å; Y80-F153 AromaticContact CD1-CD2 3.99Å; Y80-F153 HydrophobicContact CD1-CD2 3.99Å; Y80-F153 AromaticContact CD1-CE2 3.43Å; Y80-F153 HydrophobicContact CD1-CE2 3.43Å; Y80-F153 VanDerWaalsContact CD1-CE2 3.43Å; Y80-F153 HydrophobicContact CD1-CZ 4.46Å; Y80-F153 HydrophobicContact CE1-CD2 4.26Å; Y80-F153 AromaticContact CE1-CE2 3.54Å; Y80-F153 HydrophobicContact CE1-CE2 3.54Å; Y80-F153 HydrophobicContact CG-CE2 4.13Å; L81-F153 HydrophobicContact CD1-CB 4.29Å; L81-F153 HydrophobicContact CD2-CD2 4.02Å; L81-F153 HydrophobicContact CG-CD2 4.26Å; I149-F153 WeakPolarHBondContact O-CB 3.31Å; I149-F153 PolarHBondContact O-N 3.31Å; Q150-F153 WeakPolarHBondContact O-CB 3.41Å; Q150-F153 PolarHBondContact O-N 2.65Å; F153-W155 VanDerWaalsContact C-N 3.34Å; F153-W155 PolarHBondContact O-N 3.48Å; F153-V156 PolarHBondContact O-N 3.11Å; F153-S157 WeakPolarHBondContact O-CB 3.18Å; F153-S157 PolarHBondContact O-N 3.42Å; F153-L173 HydrophobicContact CE1-CD2 4.24Å; F153-L173 HydrophobicContact CZ-CD2 3.98Å; F153-L258 HydrophobicContact CE1-CD2 3.81Å; F153-M261 HydrophobicContact CE1-CE 4Å; F153-M261 HydrophobicContact CE1-SD 4.33Å; F153-M261 HydrophobicContact CE2-CE 3.92Å; F153-M261 HydrophobicContact CZ-CE 3.38Å; F153-M261 HydrophobicContact CZ-SD 4.29Å
154	L	93.8	Very high	90.9	Very high	0 Å²	0	34.1 Å²	34.1	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-67.3	-35.2	179.8	-70.1	179.4	0	0	0	112	L107 Q150 T151 Y152 V156 A158 A254 M257 L258 M261	L107-L154 HydrophobicContact CD1-CD1 3.94Å; L107-L154 HydrophobicContact CD2-CB 3.45Å; L107-L154 VanDerWaalsContact CD2-CB 3.45Å; L107-L154 HydrophobicContact CD2-CD1 3.9Å; L107-L154 HydrophobicContact CD2-CG 4.33Å; Q150-L154 HydrophobicContact CG-CD1 4.06Å; Q150-L154 HydrophobicContact CG-CG 4.36Å; Q150-L154 WeakPolarHBondContact O-CB 3.39Å; Q150-L154 WeakPolarHBondContact O-CG 3.36Å; Q150-L154 PolarHBondContact O-N 2.94Å; T151-L154 PolarHBondContact O-N 3.47Å; Y152-L154 PolarHBondContact O-N 3.2Å; L154-V156 PolarHBondContact O-N 3.25Å; L154-A158 WeakPolarHBondContact O-CB 3.34Å; L154-A158 PolarHBondContact O-N 2.94Å; L154-A158 VanDerWaalsContact O-N 3.14Å; L154-A254 HydrophobicContact CD1-CB 3.79Å; L154-M257 HydrophobicContact CB-CE 4.09Å; L154-M257 HydrophobicContact CD1-CB 4.37Å; L154-M257 HydrophobicContact CD2-CB 4.08Å; L154-L258 HydrophobicContact CD2-CD2 3.84Å; L154-L258 HydrophobicContact CD2-CG 4.02Å; L154-M261 HydrophobicContact CD2-SD 3.63Å
155	W	91.3	Very high	90.2	Very high	119 Å²	119	38 Å²	38	45%	0.451	18%	0.183	S	C	.	.	H	α-helix	trans	-60.3	-46.8	175.4	179.7	-94.5	0	0	0	112.2	R104 V108 T151 Y152 F153	R104-W155 HydrophobicContact CB-CE3 3.67Å; R104-W155 HydrophobicContact CB-CZ3 3.58Å; R104-W155 VanDerWaalsContact CZ-O 3.27Å; R104-W155 PolarHBondContact NH1-O 2.67Å; V108-W155 HydrophobicContact CG2-CE3 3.61Å; V108-W155 HydrophobicContact CG2-CZ3 3.82Å; T151-W155 VanDerWaalsContact O-CB 3.22Å; T151-W155 WeakPolarHBondContact O-CB 3.15Å; T151-W155 PolarHBondContact O-N 2.91Å; Y152-W155 PolarHBondContact O-N 3.32Å; F153-W155 VanDerWaalsContact C-N 3.34Å; F153-W155 PolarHBondContact O-N 3.48Å
156	V	89.4	Confident	89.6	Confident	56 Å²	56	37.1 Å²	37.1	34%	0.339	18%	0.175	S	C	.	.	H	α-helix	trans	-80	-47	-176.4	178.1	0	0	0	0	111.3	Y152 F153 L154	Y152-V156 HydrophobicContact CD2-CG2 4.34Å; Y152-V156 HydrophobicContact CE1-CG2 4.34Å; Y152-V156 HydrophobicContact CE2-CG2 3.92Å; Y152-V156 WeakPolarHBondContact O-CG2 3.34Å; Y152-V156 PolarHBondContact O-N 2.92Å; F153-V156 PolarHBondContact O-N 3.11Å; L154-V156 PolarHBondContact O-N 3.25Å
157	S	88.8	Confident	89.1	Confident	0 Å²	0	40 Å²	40	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-100.4	-0.1	-165.5	-74.3	0	0	0	0	115.9	F153 K159 D160 M261	F153-S157 WeakPolarHBondContact O-CB 3.18Å; F153-S157 PolarHBondContact O-N 3.42Å; S157-K159 PolarHBondContact O-N 3.49Å; S157-D160 VanDerWaalsContact CA-OD2 3.27Å; S157-D160 WeakPolarHBondContact CA-OD2 3.27Å; S157-D160 WeakPolarHBondContact CB-OD2 3.29Å; S157-D160 WeakPolarHBondContact O-CB 3.48Å; S157-D160 PolarHBondContact O-N 2.98Å; S157-D160 PolarHBondContact OG-OD2 2.87Å; S157-M261 VanDerWaalsContact O-CE 3.28Å; S157-M261 WeakPolarHBondContact O-CE 3.45Å
158	A	84.8	Confident	88.8	Confident	3 Å²	3	43.8 Å²	43.8	3%	0.025	21%	0.211	C	C	.	.	T	Hydrogen-bonded Turn	trans	-56.9	-19.1	-179.1	0	0	0	0	0	115.6	L154 M257	L154-A158 WeakPolarHBondContact O-CB 3.34Å; L154-A158 PolarHBondContact O-N 2.94Å; L154-A158 VanDerWaalsContact O-N 3.14Å; A158-M257 HydrophobicContact CB-CE 3.46Å; A158-M257 VanDerWaalsContact CB-CE 3.46Å
159	K	83.8	Confident	88.5	Confident	60 Å²	60	39.3 Å²	39.3	26%	0.261	19%	0.188	S	C	.	.	T	Hydrogen-bonded Turn	trans	-96.1	-8.2	178.8	-78.6	174.5	-177	-173.9	0	113.8	R94 D95 A98 R104 S157 C161	R94-K159 VanDerWaalsContact CA-O 3.24Å; R94-K159 WeakPolarHBondContact CA-O 3.36Å; R94-K159 HydrophobicContact CB-CB 4.21Å; R94-K159 HydrophobicContact CG-CB 4.26Å; D95-K159 PolarHBondContact N-O 3.48Å; A98-K159 VanDerWaalsContact O-CE 3.3Å; A98-K159 WeakPolarHBondContact O-CE 3.47Å; A98-K159 WeakPolarHBondContact O-CG 3.11Å; R104-K159 VanDerWaalsContact NH2-CG 3.26Å; S157-K159 PolarHBondContact O-N 3.49Å; K159-C161 PolarHBondContact O-N 3.35Å
160	D	82.7	Confident	88.3	Confident	7 Å²	7	38.1 Å²	38.1	4%	0.037	18%	0.181	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-72.6	125	-167.7	-66.6	-14.8	0	0	0	111.8	Y80 V91 R94 S157 V162	Y80-D160 PolarHBondContact OH-OD2 3.18Å; V91-D160 HydrophobicContact CG1-CB 3.6Å; V91-D160 HydrophobicContact CG2-CB 4.03Å; R94-D160 IonicContact NE-OD1 3.62Å; S157-D160 VanDerWaalsContact CA-OD2 3.27Å; S157-D160 WeakPolarHBondContact CA-OD2 3.27Å; S157-D160 WeakPolarHBondContact CB-OD2 3.29Å; S157-D160 WeakPolarHBondContact O-CB 3.48Å; S157-D160 PolarHBondContact O-N 2.98Å; S157-D160 PolarHBondContact OG-OD2 2.87Å; D160-V162 HydrophobicContact CB-CG2 4.34Å
161	C	82.1	Confident	88.2	Confident	0 Å²	0	39.2 Å²	39.2	0%	0	19%	0.188	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-95.6	91.5	167	-62.8	0	0	0	0	109.5	Y93 K159 H163 L269	Y93-C161 VanDerWaalsContact O-CB 3.3Å; Y93-C161 WeakPolarHBondContact O-CB 3.22Å; Y93-C161 PolarHBondContact O-N 3.41Å; K159-C161 PolarHBondContact O-N 3.35Å; C161-H163 PolarHBondContact O-CE1 3.06Å; C161-H163 PolarHBondContact O-ND1 3.46Å; C161-L269 VanDerWaalsContact SG-CD1 3.57Å
162	V	82.6	Confident	88.1	Confident	3 Å²	3	38.5 Å²	38.5	2%	0.018	19%	0.186	C	C	.	.			trans	-73.4	129.4	-173.5	-173	0	0	0	0	111.4	Y80 T84 D160 V164 L166 T169 G266	Y80-V162 HydrophobicContact CE2-CG1 4.41Å; Y80-V162 HydrophobicContact CE2-CG2 3.81Å; Y80-V162 WeakPolarHBondContact OH-CG2 3.47Å; T84-V162 HydrophobicContact CG2-CG1 4.18Å; D160-V162 HydrophobicContact CB-CG2 4.34Å; V162-V164 WeakPolarHBondContact CG1-O 3.4Å; V162-L166 WeakPolarHBondContact O-CD2 3.3Å; V162-T169 HydrophobicContact CB-CG2 4.25Å; V162-T169 HydrophobicContact CG1-CG2 4.13Å; V162-T169 HydrophobicContact CG2-CG2 4.26Å; V162-G266 PolarHBondContact O-N 3.46Å
163	H	81.7	Confident	88.1	Confident	42 Å²	42	32 Å²	32	19%	0.194	16%	0.16	C	C	.	.			trans	-114.6	-5.6	178.8	-74.4	73.1	0	0	0	114.2	A90 P92 C161 R267 F268	A90-H163 PolarHBondContact O-N 3.48Å; P92-H163 HydrophobicContact CG-CB 4.18Å; C161-H163 PolarHBondContact O-CE1 3.06Å; C161-H163 PolarHBondContact O-ND1 3.46Å; H163-R267 PolarHBondContact CE1-O 3.02Å; H163-R267 PolarHBondContact NE2-O 3.31Å; H163-F268 AromaticContact CD2-CE1 3.92Å; H163-F268 AromaticContact NE2-CD1 3.86Å; H163-F268 AromaticContact NE2-CE1 3.89Å
164	V	79.5	Confident	88.1	Confident	45 Å²	45	32.6 Å²	32.6	27%	0.273	16%	0.163	S	C	.	.	S	Bend	trans	-110.4	145.6	-177.7	173.7	0	0	0	0	110.3	A90 V162 L166	A90-V164 HydrophobicContact CB-CB 4.13Å; A90-V164 HydrophobicContact CB-CG2 4.03Å; V162-V164 WeakPolarHBondContact CG1-O 3.4Å; V164-L166 VanDerWaalsContact C-N 3.31Å; V164-L166 PolarHBondContact O-N 3.5Å
165	H	81.6	Confident	88.3	Confident	104 Å²	104	34 Å²	34	48%	0.481	17%	0.169	S	C	.	.	S	Bend	trans	48.3	45	-176.5	-57	113.9	0	0	0	114.4	N167 L168 T169	H165-N167 VanDerWaalsContact C-N 3.32Å; H165-N167 PolarHBondContact O-N 3.46Å; H165-N167 VanDerWaalsContact O-N 3.13Å; H165-L168 HydrophobicContact CB-CB 4.3Å; H165-L168 PolarHBondContact O-N 2.63Å; H165-L168 VanDerWaalsContact O-N 3.15Å; H165-T169 PolarHBondContact O-N 2.78Å; H165-T169 PolarHBondContact O-OG1 2.9Å; H165-T169 VanDerWaalsContact O-OG1 3.14Å
166	L	86.4	Confident	88.6	Confident	48 Å²	48	28.4 Å²	28.4	25%	0.251	15%	0.148	S	C	.	.	H	α-helix	trans	-50.4	-43.9	-170.2	-64	172.7	0	0	0	114.7	V162 V164 R170 V265	V162-L166 WeakPolarHBondContact O-CD2 3.3Å; V164-L166 VanDerWaalsContact C-N 3.31Å; V164-L166 PolarHBondContact O-N 3.5Å; L166-R170 WeakPolarHBondContact O-CB 3.49Å; L166-R170 WeakPolarHBondContact O-CG 3.49Å; L166-R170 PolarHBondContact O-N 3.27Å; L166-V265 HydrophobicContact CB-CG1 4.39Å; L166-V265 HydrophobicContact CD2-CG1 3.55Å
167	N	87.8	Confident	88.9	Confident	61 Å²	61	26.6 Å²	26.6	33%	0.326	14%	0.137	S	C	.	.	H	α-helix	trans	-70.1	-45.4	-177.4	-65.4	-20.6	0	0	0	111.5	G28 H165 R170 C171	G28-N167 WeakPolarHBondContact CA-OD1 3.35Å; H165-N167 VanDerWaalsContact C-N 3.32Å; H165-N167 PolarHBondContact O-N 3.46Å; H165-N167 VanDerWaalsContact O-N 3.13Å; N167-R170 PolarHBondContact O-N 2.94Å; N167-C171 PolarHBondContact O-N 2.94Å; N167-C171 PolarHBondContact O-SG 3.07Å; N167-C171 VanDerWaalsContact O-SG 3.36Å
168	L	90.3	Very high	89.3	Confident	83 Å²	83	26.7 Å²	26.7	44%	0.435	14%	0.137	S	C	.	.	H	α-helix	trans	-63.4	-43.2	177.4	-177.8	63.7	0	0	0	111.3	W76 F79 H165 R170 C171 G172	W76-L168 PolarHBondContact NE1-O 3.29Å; F79-L168 HydrophobicContact CD1-CD2 4.33Å; F79-L168 HydrophobicContact CE1-CD2 3.56Å; F79-L168 HydrophobicContact CZ-CD2 4.07Å; H165-L168 HydrophobicContact CB-CB 4.3Å; H165-L168 PolarHBondContact O-N 2.63Å; H165-L168 VanDerWaalsContact O-N 3.15Å; L168-R170 PolarHBondContact O-N 2.89Å; L168-C171 PolarHBondContact O-N 3.45Å; L168-G172 PolarHBondContact O-N 3.48Å
169	T	91.6	Very high	89.9	Confident	2 Å²	2	26.6 Å²	26.6	1%	0.012	14%	0.136	C	C	.	.	H	α-helix	trans	-63.3	-41.6	176.6	-56.9	0	0	0	0	111.3	W76 Y80 V162 H165 L173 V265	W76-T169 HydrophobicContact CZ2-CG2 4.31Å; Y80-T169 HydrophobicContact CD2-CG2 4.44Å; Y80-T169 HydrophobicContact CE2-CG2 4.12Å; V162-T169 HydrophobicContact CB-CG2 4.25Å; V162-T169 HydrophobicContact CG1-CG2 4.13Å; V162-T169 HydrophobicContact CG2-CG2 4.26Å; H165-T169 PolarHBondContact O-N 2.78Å; H165-T169 PolarHBondContact O-OG1 2.9Å; H165-T169 VanDerWaalsContact O-OG1 3.14Å; T169-L173 HydrophobicContact CG2-CD1 3.93Å; T169-L173 HydrophobicContact CG2-CG 4.38Å; T169-L173 WeakPolarHBondContact O-CB 3.15Å; T169-L173 VanDerWaalsContact O-CG 3.25Å; T169-L173 WeakPolarHBondContact O-CG 3.31Å; T169-L173 PolarHBondContact O-N 3.26Å; T169-V265 HydrophobicContact CG2-CG1 4.49Å; T169-V265 HydrophobicContact CG2-CG2 3.93Å
170	R	92.8	Very high	90.5	Very high	8 Å²	8	23.7 Å²	23.7	3%	0.03	12%	0.124	C	C	.	.	H	α-helix	trans	-63.6	-46.6	176	-77.5	175.5	-172.3	130.3	4.3	112.4	L166 N167 L168 M174 V265	L166-R170 WeakPolarHBondContact O-CB 3.49Å; L166-R170 WeakPolarHBondContact O-CG 3.49Å; L166-R170 PolarHBondContact O-N 3.27Å; N167-R170 PolarHBondContact O-N 2.94Å; L168-R170 PolarHBondContact O-N 2.89Å; R170-M174 WeakPolarHBondContact O-CB 3.45Å; R170-M174 PolarHBondContact O-N 2.9Å; R170-V265 HydrophobicContact CG-CB 4.15Å; R170-V265 HydrophobicContact CG-CG1 3.92Å; R170-V265 HydrophobicContact CG-CG2 4.5Å; R170-V265 PolarHBondContact NH2-O 3.16Å
171	C	94.6	Very high	91.1	Very high	23 Å²	23	25.3 Å²	25.3	16%	0.155	13%	0.132	C	C	.	.	H	α-helix	trans	-63	-45.5	178.5	-69.5	0	0	0	0	111.5	L35 N167 L168 M174 F175	L35-C171 HydrophobicContact CD2-CB 4.04Å; N167-C171 PolarHBondContact O-N 2.94Å; N167-C171 PolarHBondContact O-SG 3.07Å; N167-C171 VanDerWaalsContact O-SG 3.36Å; L168-C171 PolarHBondContact O-N 3.45Å; C171-M174 PolarHBondContact O-N 2.93Å; C171-F175 VanDerWaalsContact O-CB 3.25Å; C171-F175 WeakPolarHBondContact O-CB 3.33Å; C171-F175 PolarHBondContact O-N 3.3Å
172	G	95.2	Very high	91.7	Very high	6 Å²	6	25.3 Å²	25.3	6%	0.062	13%	0.132	C	C	.	.	H	α-helix	trans	-69.4	-37.2	-179.4	0	0	0	0	0	114.2	W76 L168 F175 T176	W76-G172 VanDerWaalsContact CE2-CA 3.45Å; L168-G172 PolarHBondContact O-N 3.48Å; G172-F175 PolarHBondContact O-N 3.4Å; G172-T176 WeakPolarHBondContact O-CB 3.48Å; G172-T176 PolarHBondContact O-N 3.07Å; G172-T176 PolarHBondContact O-OG1 3.38Å
173	L	95.4	Very high	92.3	Very high	3 Å²	3	25.5 Å²	25.5	2%	0.016	13%	0.133	C	C	.	.	H	α-helix	trans	-62.2	-45.1	172	-74.6	171.4	0	0	0	111.7	W76 F153 T169 T176 L177 L258 M261 W262 V265	W76-L173 HydrophobicContact CH2-CB 4.41Å; W76-L173 HydrophobicContact CH2-CD2 3.58Å; W76-L173 HydrophobicContact CH2-CG 3.61Å; W76-L173 HydrophobicContact CZ2-CG 4.15Å; W76-L173 HydrophobicContact CZ3-CD2 4.17Å; W76-L173 HydrophobicContact CZ3-CG 4.47Å; F153-L173 HydrophobicContact CE1-CD2 4.24Å; F153-L173 HydrophobicContact CZ-CD2 3.98Å; T169-L173 HydrophobicContact CG2-CD1 3.93Å; T169-L173 HydrophobicContact CG2-CG 4.38Å; T169-L173 WeakPolarHBondContact O-CB 3.15Å; T169-L173 VanDerWaalsContact O-CG 3.25Å; T169-L173 WeakPolarHBondContact O-CG 3.31Å; T169-L173 PolarHBondContact O-N 3.26Å; L173-T176 PolarHBondContact O-N 2.91Å; L173-L177 WeakPolarHBondContact O-CB 3.38Å; L173-L177 PolarHBondContact O-N 3.04Å; L173-L258 HydrophobicContact CD2-CD2 3.74Å; L173-M261 HydrophobicContact CD1-CB 4.17Å; L173-M261 HydrophobicContact CD2-CB 4.13Å; L173-M261 HydrophobicContact CD2-CE 4.19Å; L173-W262 HydrophobicContact CB-CB 4.17Å; L173-W262 HydrophobicContact CD1-CB 4.1Å; L173-V265 HydrophobicContact CD1-CG2 3.63Å
174	M	94.8	Very high	92.8	Very high	11 Å²	11	24.5 Å²	24.5	5%	0.054	13%	0.127	C	C	.	.	H	α-helix	trans	-67.3	-40.4	177.5	-82.5	-65.6	109.8	0	0	112.5	A36 R170 C171 L177 T178 Y259 W262	A36-M174 HydrophobicContact CB-CB 4.01Å; A36-M174 HydrophobicContact CB-CG 4.49Å; A36-M174 HydrophobicContact CB-SD 4.31Å; R170-M174 WeakPolarHBondContact O-CB 3.45Å; R170-M174 PolarHBondContact O-N 2.9Å; C171-M174 PolarHBondContact O-N 2.93Å; M174-L177 HydrophobicContact CE-CD1 3.73Å; M174-L177 WeakPolarHBondContact O-CB 3.31Å; M174-L177 PolarHBondContact O-N 3.41Å; M174-T178 WeakPolarHBondContact O-CB 3.4Å; M174-T178 PolarHBondContact O-N 3.47Å; M174-T178 PolarHBondContact O-OG1 3.48Å; M174-Y259 HydrophobicContact CE-CD2 4.22Å; M174-W262 HydrophobicContact CE-CB 3.69Å; M174-W262 HydrophobicContact CE-CD2 3.64Å; M174-W262 HydrophobicContact CE-CE3 4.09Å; M174-W262 HydrophobicContact CE-CG 3.45Å; M174-W262 VanDerWaalsContact CE-CG 3.45Å; M174-W262 HydrophobicContact CG-CD2 4.44Å; M174-W262 HydrophobicContact CG-CG 4.18Å; M174-W262 HydrophobicContact SD-CD2 4.43Å; M174-W262 HydrophobicContact SD-CG 4.49Å
175	F	97.1	Very high	93.4	Very high	31 Å²	31	24.5 Å²	24.5	14%	0.136	13%	0.125	C	C	.	.	H	α-helix	trans	-63.4	-43.4	175.7	-178.8	-93.8	0	0	0	111.8	V39 M69 L72 A73 C171 G172 L177 T178 T179	V39-F175 HydrophobicContact CG1-CD2 4.41Å; V39-F175 HydrophobicContact CG1-CE2 4.11Å; V39-F175 HydrophobicContact CG2-CD2 4.44Å; V39-F175 HydrophobicContact CG2-CE2 4.42Å; M69-F175 HydrophobicContact CB-CZ 4.32Å; M69-F175 HydrophobicContact CG-CZ 4.38Å; M69-F175 WeakPolarHBondContact O-CE1 3.2Å; L72-F175 HydrophobicContact CB-CE1 3.61Å; L72-F175 HydrophobicContact CB-CZ 3.8Å; L72-F175 HydrophobicContact CD1-CZ 3.96Å; A73-F175 HydrophobicContact CB-CD1 4.22Å; A73-F175 HydrophobicContact CB-CE1 4.13Å; C171-F175 VanDerWaalsContact O-CB 3.25Å; C171-F175 WeakPolarHBondContact O-CB 3.33Å; C171-F175 PolarHBondContact O-N 3.3Å; G172-F175 PolarHBondContact O-N 3.4Å; F175-L177 VanDerWaalsContact C-N 3.33Å; F175-L177 PolarHBondContact O-N 3.08Å; F175-T178 PolarHBondContact O-N 3.34Å; F175-T179 PolarHBondContact O-N 2.91Å; F175-T179 PolarHBondContact O-OG1 3.48Å
176	T	97.5	Very high	93.8	Very high	0 Å²	0	20.3 Å²	20.3	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-63	-42.2	174.9	-51.7	0	0	0	0	110.4	A73 I77 F146 G172 L173 T179 N180 L258	A73-T176 HydrophobicContact CB-CG2 4.32Å; I77-T176 HydrophobicContact CD1-CG2 4.1Å; F146-T176 HydrophobicContact CE2-CG2 4.46Å; F146-T176 HydrophobicContact CZ-CG2 4.44Å; G172-T176 WeakPolarHBondContact O-CB 3.48Å; G172-T176 PolarHBondContact O-N 3.07Å; G172-T176 PolarHBondContact O-OG1 3.38Å; L173-T176 PolarHBondContact O-N 2.91Å; T176-T179 WeakPolarHBondContact O-CB 3.39Å; T176-T179 PolarHBondContact O-N 3.18Å; T176-N180 PolarHBondContact O-N 3.33Å; T176-N180 PolarHBondContact O-ND2 3.44Å; T176-L258 HydrophobicContact CG2-CD1 3.61Å; T176-L258 HydrophobicContact CG2-CD2 4.16Å
177	L	96.2	Very high	93.9	Very high	19 Å²	19	18.1 Å²	18.1	10%	0.099	10%	0.097	C	C	.	.	H	α-helix	trans	-59.8	-49.3	175	-179.7	158.8	0	0	0	111	L173 M174 F175 T179 N180 L181 S255 L258 Y259	L173-L177 WeakPolarHBondContact O-CB 3.38Å; L173-L177 PolarHBondContact O-N 3.04Å; M174-L177 HydrophobicContact CE-CD1 3.73Å; M174-L177 WeakPolarHBondContact O-CB 3.31Å; M174-L177 PolarHBondContact O-N 3.41Å; F175-L177 VanDerWaalsContact C-N 3.33Å; F175-L177 PolarHBondContact O-N 3.08Å; L177-T179 PolarHBondContact O-N 2.82Å; L177-N180 PolarHBondContact O-N 3.26Å; L177-N180 VanDerWaalsContact O-N 3.1Å; L177-L181 HydrophobicContact CD2-CD1 3.56Å; L177-L181 HydrophobicContact CD2-CG 4.03Å; L177-L181 PolarHBondContact O-N 3.48Å; L177-S255 VanDerWaalsContact CD1-O 3.31Å; L177-S255 WeakPolarHBondContact CD1-O 3.28Å; L177-L258 HydrophobicContact CB-CB 4.1Å; L177-L258 HydrophobicContact CB-CD1 4.25Å; L177-L258 HydrophobicContact CD1-CB 4.43Å; L177-Y259 HydrophobicContact CD1-CD2 4.27Å
178	T	96.6	Very high	93.9	Very high	2 Å²	2	15.4 Å²	15.4	1%	0.012	8%	0.082	C	C	.	.	H	α-helix	trans	-58.5	-37.2	176.1	-66.9	0	0	0	0	112	A36 V39 L40 M69 M174 F175 L181 A182	A36-T178 WeakPolarHBondContact CA-OG1 3.23Å; A36-T178 WeakPolarHBondContact CB-OG1 3.25Å; A36-T178 PolarHBondContact O-OG1 2.85Å; V39-T178 HydrophobicContact CB-CG2 3.95Å; V39-T178 HydrophobicContact CG1-CG2 3.65Å; L40-T178 HydrophobicContact CB-CG2 3.71Å; L40-T178 HydrophobicContact CD1-CG2 4.21Å; M69-T178 HydrophobicContact CE-CG2 4.09Å; M174-T178 WeakPolarHBondContact O-CB 3.4Å; M174-T178 PolarHBondContact O-N 3.47Å; M174-T178 PolarHBondContact O-OG1 3.48Å; F175-T178 PolarHBondContact O-N 3.34Å; T178-L181 PolarHBondContact O-N 2.98Å; T178-A182 WeakPolarHBondContact O-CB 3.16Å; T178-A182 PolarHBondContact O-N 3.34Å
179	T	97.4	Very high	93.7	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-62.3	-42.7	175.4	-54.9	0	0	0	0	111.7	M69 M70 F146 F175 T176 L177 A182 I183	M69-T179 HydrophobicContact CB-CG2 3.85Å; M70-T179 HydrophobicContact CG-CG2 4.02Å; F146-T179 HydrophobicContact CZ-CG2 4.2Å; F175-T179 PolarHBondContact O-N 2.91Å; F175-T179 PolarHBondContact O-OG1 3.48Å; T176-T179 WeakPolarHBondContact O-CB 3.39Å; T176-T179 PolarHBondContact O-N 3.18Å; L177-T179 PolarHBondContact O-N 2.82Å; T179-A182 PolarHBondContact O-N 2.93Å; T179-I183 HydrophobicContact CG2-CD1 4.05Å; T179-I183 VanDerWaalsContact O-CG1 3.27Å; T179-I183 WeakPolarHBondContact O-CG1 3.46Å; T179-I183 PolarHBondContact O-N 2.92Å
180	N	97	Very high	93.4	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-66.2	-40.6	175.6	-75.2	-101.5	0	0	0	111.8	Q150 T176 L177 A182 I183 W184 S251 A254 S255	Q150-N180 VanDerWaalsContact NE2-CG 3.28Å; Q150-N180 PolarHBondContact NE2-ND2 3.06Å; Q150-N180 PolarHBondContact NE2-OD1 2.88Å; Q150-N180 PolarHBondContact OE1-OD1 2.9Å; T176-N180 PolarHBondContact O-N 3.33Å; T176-N180 PolarHBondContact O-ND2 3.44Å; L177-N180 PolarHBondContact O-N 3.26Å; L177-N180 VanDerWaalsContact O-N 3.1Å; N180-A182 VanDerWaalsContact C-N 3.33Å; N180-A182 PolarHBondContact O-N 3.5Å; N180-I183 PolarHBondContact O-N 3.11Å; N180-W184 WeakPolarHBondContact O-CB 3.43Å; N180-W184 PolarHBondContact O-N 3.41Å; N180-S251 WeakPolarHBondContact O-CB 3.5Å; N180-A254 WeakPolarHBondContact OD1-CB 3.36Å; N180-S255 WeakPolarHBondContact CB-OG 3.41Å
181	L	94.2	Very high	92.9	Very high	40 Å²	40	15.7 Å²	15.7	21%	0.209	9%	0.086	C	C	.	.	H	α-helix	trans	-64.6	-36.4	175	-67.2	-177.6	0	0	0	112.5	L40 L177 T178 W184 M185	L40-L181 HydrophobicContact CD1-CB 3.86Å; L40-L181 HydrophobicContact CD2-CD1 4.11Å; L177-L181 HydrophobicContact CD2-CD1 3.56Å; L177-L181 HydrophobicContact CD2-CG 4.03Å; L177-L181 PolarHBondContact O-N 3.48Å; T178-L181 PolarHBondContact O-N 2.98Å; L181-W184 PolarHBondContact O-N 2.78Å; L181-M185 WeakPolarHBondContact O-CB 3.42Å; L181-M185 WeakPolarHBondContact O-CG 3.4Å; L181-M185 PolarHBondContact O-N 3.42Å
182	A	95.4	Very high	92.3	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-67.6	-43.1	175.1	0	0	0	0	0	111.9	A43 I47 L66 M69 T178 T179 N180 W184 M185 A186	A43-A182 HydrophobicContact CB-CB 3.69Å; I47-A182 HydrophobicContact CD1-CB 4.46Å; I47-A182 WeakPolarHBondContact CD1-O 3.36Å; L66-A182 HydrophobicContact CD2-CB 3.83Å; M69-A182 HydrophobicContact CE-CB 4.08Å; M69-A182 HydrophobicContact SD-CB 4.36Å; T178-A182 WeakPolarHBondContact O-CB 3.16Å; T178-A182 PolarHBondContact O-N 3.34Å; T179-A182 PolarHBondContact O-N 2.93Å; N180-A182 VanDerWaalsContact C-N 3.33Å; N180-A182 PolarHBondContact O-N 3.5Å; A182-W184 VanDerWaalsContact C-N 3.34Å; A182-M185 PolarHBondContact O-N 2.82Å; A182-A186 WeakPolarHBondContact O-CB 3.44Å; A182-A186 PolarHBondContact O-N 2.88Å
183	I	94.7	Very high	91.7	Very high	7 Å²	7	17.6 Å²	17.6	4%	0.036	10%	0.096	C	C	.	.	H	α-helix	trans	-61.3	-44.7	173.7	-67.7	164.5	0	0	0	110.2	L66 M70 F146 T179 N180 A186 A187	L66-I183 HydrophobicContact CD2-CG1 4.34Å; M70-I183 HydrophobicContact CG-CD1 3.91Å; M70-I183 HydrophobicContact SD-CD1 3.89Å; F146-I183 HydrophobicContact CD1-CD1 4.17Å; F146-I183 HydrophobicContact CE1-CD1 3.74Å; T179-I183 HydrophobicContact CG2-CD1 4.05Å; T179-I183 VanDerWaalsContact O-CG1 3.27Å; T179-I183 WeakPolarHBondContact O-CG1 3.46Å; T179-I183 PolarHBondContact O-N 2.92Å; N180-I183 PolarHBondContact O-N 3.11Å; I183-A186 PolarHBondContact O-N 3.46Å; I183-A187 WeakPolarHBondContact O-CB 3.47Å; I183-A187 PolarHBondContact O-N 3.21Å
184	W	93.7	Very high	91	Very high	21 Å²	21	20 Å²	20	8%	0.08	11%	0.107	C	C	.	.	H	α-helix	trans	-58.2	-49.3	175.3	169.4	77.1	0	0	0	112.1	N180 L181 A182 A187 V188 L252 I539 F543	N180-W184 WeakPolarHBondContact O-CB 3.43Å; N180-W184 PolarHBondContact O-N 3.41Å; L181-W184 PolarHBondContact O-N 2.78Å; A182-W184 VanDerWaalsContact C-N 3.34Å; W184-A187 WeakPolarHBondContact O-CB 3.46Å; W184-A187 PolarHBondContact O-N 2.88Å; W184-V188 HydrophobicContact CD2-CG2 4.5Å; W184-V188 HydrophobicContact CZ2-CG2 4.23Å; W184-V188 WeakPolarHBondContact O-CG2 3.34Å; W184-V188 PolarHBondContact O-N 3.24Å; W184-L252 HydrophobicContact CD2-CD2 4.15Å; W184-L252 HydrophobicContact CG-CD2 4.11Å; W184-L252 HydrophobicContact CG-CG 4.33Å; W184-I539 HydrophobicContact CH2-CG2 4.3Å; W184-I539 HydrophobicContact CZ2-CG2 4.5Å; W184-F543 AromaticContact CH2-CE2 3.77Å; W184-F543 HydrophobicContact CH2-CE2 3.77Å; W184-F543 AromaticContact CH2-CZ 3.92Å; W184-F543 HydrophobicContact CH2-CZ 3.92Å; W184-F543 AromaticContact CZ2-CE2 3.56Å; W184-F543 HydrophobicContact CZ2-CE2 3.56Å; W184-F543 AromaticContact CZ2-CZ 3.92Å; W184-F543 HydrophobicContact CZ2-CZ 3.92Å
185	M	90.8	Very high	90.2	Very high	46 Å²	46	20.7 Å²	20.7	23%	0.227	11%	0.11	C	C	.	.	H	α-helix	trans	-60.9	-47.7	177.8	-79.3	-63	-64.1	0	0	112.2	I47 L181 A182 A187 V188 V189	I47-M185 HydrophobicContact CD1-CB 4.09Å; L181-M185 WeakPolarHBondContact O-CB 3.42Å; L181-M185 WeakPolarHBondContact O-CG 3.4Å; L181-M185 PolarHBondContact O-N 3.42Å; A182-M185 PolarHBondContact O-N 2.82Å; M185-A187 PolarHBondContact O-N 2.88Å; M185-V188 PolarHBondContact O-N 3.09Å; M185-V189 WeakPolarHBondContact O-CG2 3.43Å; M185-V189 PolarHBondContact O-N 3.09Å
186	A	90.8	Very high	89.3	Confident	15 Å²	15	20.7 Å²	20.7	12%	0.124	11%	0.114	C	C	.	.	H	α-helix	trans	-60.9	-37.4	177	0	0	0	0	0	110.9	I47 L66 A182 I183 V189 D190	I47-A186 HydrophobicContact CD1-CB 3.93Å; I47-A186 HydrophobicContact CG1-CB 4.12Å; I47-A186 HydrophobicContact CG2-CB 4.32Å; L66-A186 HydrophobicContact CD1-CB 3.58Å; A182-A186 WeakPolarHBondContact O-CB 3.44Å; A182-A186 PolarHBondContact O-N 2.88Å; I183-A186 PolarHBondContact O-N 3.46Å; A186-V189 PolarHBondContact O-N 3.27Å; A186-D190 PolarHBondContact O-N 3.01Å; A186-D190 VanDerWaalsContact O-N 3.08Å
187	A	89.4	Confident	88.3	Confident	3 Å²	3	26.2 Å²	26.2	3%	0.025	14%	0.14	C	C	.	.	H	α-helix	trans	-61.8	-58.5	178	0	0	0	0	0	110	I183 W184 M185 V189 D190 E191 Y244 I248	I183-A187 WeakPolarHBondContact O-CB 3.47Å; I183-A187 PolarHBondContact O-N 3.21Å; W184-A187 WeakPolarHBondContact O-CB 3.46Å; W184-A187 PolarHBondContact O-N 2.88Å; M185-A187 PolarHBondContact O-N 2.88Å; A187-V189 PolarHBondContact O-N 3.39Å; A187-D190 PolarHBondContact O-N 3.1Å; A187-D190 VanDerWaalsContact O-N 3.07Å; A187-E191 PolarHBondContact O-N 2.81Å; A187-Y244 VanDerWaalsContact C-CE1 3.42Å; A187-Y244 WeakPolarHBondContact CA-OH 3.4Å; A187-Y244 HydrophobicContact CB-CE1 3.65Å; A187-Y244 WeakPolarHBondContact O-CE1 3.36Å; A187-Y244 PolarHBondContact O-OH 2.62Å; A187-I248 HydrophobicContact CB-CD1 4.41Å; A187-I248 HydrophobicContact CB-CG1 3.76Å
188	V	86.9	Confident	87.4	Confident	3 Å²	3	28 Å²	28	2%	0.018	15%	0.154	C	C	.	.	H	α-helix	trans	-52.5	-40.1	179.9	168.4	0	0	0	0	112.7	W184 M185 S192 I248 N538 I539	W184-V188 HydrophobicContact CD2-CG2 4.5Å; W184-V188 HydrophobicContact CZ2-CG2 4.23Å; W184-V188 WeakPolarHBondContact O-CG2 3.34Å; W184-V188 PolarHBondContact O-N 3.24Å; M185-V188 PolarHBondContact O-N 3.09Å; V188-S192 WeakPolarHBondContact O-CB 3.4Å; V188-S192 PolarHBondContact O-N 2.83Å; V188-S192 VanDerWaalsContact O-N 3.08Å; V188-S192 PolarHBondContact O-OG 2.77Å; V188-I248 HydrophobicContact CG2-CD1 4.04Å; V188-I248 HydrophobicContact CG2-CG1 4.47Å; V188-I248 HydrophobicContact CG2-CG2 4.36Å; V188-N538 HydrophobicContact CG1-CB 3.94Å; V188-I539 HydrophobicContact CG1-CB 4.4Å; V188-I539 HydrophobicContact CG1-CG1 3.56Å
189	V	85.3	Confident	86.3	Confident	36 Å²	36	31.7 Å²	31.7	22%	0.218	17%	0.168	C	C	.	.	H	α-helix	trans	-65.4	-49.9	177.2	166.4	0	0	0	0	111.6	I47 A51 M185 A186 A187 E191 S192 V193	I47-V189 HydrophobicContact CG2-CB 4.15Å; I47-V189 HydrophobicContact CG2-CG1 4.44Å; I47-V189 HydrophobicContact CG2-CG2 3.86Å; A51-V189 HydrophobicContact CB-CG1 3.52Å; M185-V189 WeakPolarHBondContact O-CG2 3.43Å; M185-V189 PolarHBondContact O-N 3.09Å; A186-V189 PolarHBondContact O-N 3.27Å; A187-V189 PolarHBondContact O-N 3.39Å; V189-E191 VanDerWaalsContact C-N 3.34Å; V189-E191 PolarHBondContact O-N 2.89Å; V189-S192 PolarHBondContact O-N 2.97Å; V189-V193 WeakPolarHBondContact O-CG2 3.36Å; V189-V193 PolarHBondContact O-N 3.37Å
190	D	85	Confident	85.2	Confident	52 Å²	52	35.2 Å²	35.2	28%	0.278	19%	0.193	S	C	.	.	H	α-helix	trans	-64.2	-37.7	-179.8	-178.3	64.4	0	0	0	111.9	A186 A187 S192 V193 H194 Y240 Y244	A186-D190 PolarHBondContact O-N 3.01Å; A186-D190 VanDerWaalsContact O-N 3.08Å; A187-D190 PolarHBondContact O-N 3.1Å; A187-D190 VanDerWaalsContact O-N 3.07Å; D190-S192 PolarHBondContact O-N 3.25Å; D190-V193 PolarHBondContact O-N 3.06Å; D190-H194 WeakPolarHBondContact O-CB 3.17Å; D190-H194 PolarHBondContact O-N 2.78Å; D190-Y240 PolarHBondContact OD2-OH 3.3Å; D190-Y244 WeakPolarHBondContact CB-OH 3.41Å; D190-Y244 PolarHBondContact OD2-OH 3.43Å
191	E	83.4	Confident	84.1	Confident	11 Å²	11	38.3 Å²	38.3	5%	0.051	21%	0.214	C	C	.	.	H	α-helix	trans	-61.5	-44.4	172.8	-173.5	173.9	-166.2	0	0	111.9	A187 V189 V193 H194 Q195 Y244 I248 R516	A187-E191 PolarHBondContact O-N 2.81Å; V189-E191 VanDerWaalsContact C-N 3.34Å; V189-E191 PolarHBondContact O-N 2.89Å; E191-V193 VanDerWaalsContact C-N 3.35Å; E191-V193 PolarHBondContact O-N 3.2Å; E191-H194 PolarHBondContact O-N 3.3Å; E191-Q195 VanDerWaalsContact O-CB 3.32Å; E191-Q195 WeakPolarHBondContact O-CB 3.5Å; E191-Q195 WeakPolarHBondContact O-CG 3.28Å; E191-Q195 PolarHBondContact O-N 3.31Å; E191-Y244 HydrophobicContact CB-CD1 3.75Å; E191-Y244 HydrophobicContact CB-CE1 3.63Å; E191-Y244 HydrophobicContact CG-CD1 4.14Å; E191-I248 WeakPolarHBondContact OE2-CD1 3.38Å; E191-R516 IonicContact OE1-CZ 3.97Å; E191-R516 IonicContact OE1-NH1 3.87Å; E191-R516 PolarHBondContact OE1-NH1 3.33Å; E191-R516 IonicContact OE1-NH2 2.67Å; E191-R516 PolarHBondContact OE1-NH2 3.49Å; E191-R516 IonicContact OE2-NH1 3.69Å
192	S	82.4	Confident	82.8	Confident	17 Å²	17	40.2 Å²	40.2	12%	0.119	23%	0.231	C	C	.	.	H	α-helix	trans	-65.1	-39.4	-180	-56.6	0	0	0	0	112	V188 V189 D190 S196 N538	V188-S192 WeakPolarHBondContact O-CB 3.4Å; V188-S192 PolarHBondContact O-N 2.83Å; V188-S192 VanDerWaalsContact O-N 3.08Å; V188-S192 PolarHBondContact O-OG 2.77Å; V189-S192 PolarHBondContact O-N 2.97Å; D190-S192 PolarHBondContact O-N 3.25Å; S192-S196 WeakPolarHBondContact O-CB 3.5Å; S192-S196 PolarHBondContact O-N 3.49Å; S192-N538 WeakPolarHBondContact CA-ND2 3.44Å; S192-N538 PolarHBondContact OG-ND2 3.31Å
193	V	81.1	Confident	81.3	Confident	52 Å²	52	45.3 Å²	45.3	32%	0.315	26%	0.255	S	S	.	.	H	α-helix	trans	-66.1	-48.3	176.3	170.6	0	0	0	0	110.5	V189 D190 E191 Q195 S196 H197	V189-V193 WeakPolarHBondContact O-CG2 3.36Å; V189-V193 PolarHBondContact O-N 3.37Å; D190-V193 PolarHBondContact O-N 3.06Å; E191-V193 VanDerWaalsContact C-N 3.35Å; E191-V193 PolarHBondContact O-N 3.2Å; V193-Q195 VanDerWaalsContact C-N 3.34Å; V193-Q195 PolarHBondContact O-N 2.99Å; V193-S196 WeakPolarHBondContact O-CB 3.18Å; V193-S196 PolarHBondContact O-N 2.94Å; V193-H197 PolarHBondContact O-CD2 3.43Å; V193-H197 PolarHBondContact O-N 3.47Å
194	H	80.9	Confident	79.5	Confident	53 Å²	53	47.1 Å²	47.1	25%	0.245	27%	0.268	C	S	.	.	H	α-helix	trans	-58.5	-46.7	178.1	174.6	-100.6	0	0	0	112.2	D190 E191 S196 H197 S198 F241	D190-H194 WeakPolarHBondContact O-CB 3.17Å; D190-H194 PolarHBondContact O-N 2.78Å; E191-H194 PolarHBondContact O-N 3.3Å; H194-S196 VanDerWaalsContact C-N 3.32Å; H194-S196 PolarHBondContact O-N 3.32Å; H194-H197 PolarHBondContact O-N 2.87Å; H194-S198 PolarHBondContact O-N 3.49Å; H194-F241 HydrophobicContact CB-CD1 4.18Å; H194-F241 HydrophobicContact CB-CE1 3.52Å; H194-F241 HydrophobicContact CB-CZ 3.94Å; H194-F241 AromaticContact CD2-CD2 3.91Å; H194-F241 AromaticContact CD2-CE1 3.48Å; H194-F241 VanDerWaalsContact CD2-CE1 3.48Å; H194-F241 WeakPolarHBondContact CD2-CE1 3.32Å; H194-F241 AromaticContact CD2-CE2 3.27Å; H194-F241 WeakPolarHBondContact CD2-CE2 3.39Å; H194-F241 AromaticContact CD2-CZ 3.03Å; H194-F241 WeakPolarHBondContact CD2-CZ 3.47Å; H194-F241 AromaticContact CE1-CD1 3.89Å; H194-F241 AromaticContact CE1-CD2 3.48Å; H194-F241 VanDerWaalsContact CE1-CD2 3.48Å; H194-F241 WeakPolarHBondContact CE1-CD2 3.3Å; H194-F241 AromaticContact CE1-CE2 3.67Å; H194-F241 AromaticContact CE1-CG 3.62Å; H194-F241 AromaticContact CE1-CZ 3.96Å; H194-F241 AromaticContact CG-CD1 3.65Å; H194-F241 AromaticContact CG-CE1 3.21Å; H194-F241 AromaticContact CG-CE2 3.85Å; H194-F241 AromaticContact CG-CZ 3.34Å; H194-F241 AromaticContact ND1-CD1 3.53Å; H194-F241 AromaticContact ND1-CD2 3.99Å; H194-F241 AromaticContact ND1-CE1 3.63Å; H194-F241 AromaticContact ND1-CG 3.75Å; H194-F241 AromaticContact ND1-CZ 3.92Å; H194-F241 AromaticContact NE2-CD2 3.42Å; H194-F241 WeakPolarHBondContact NE2-CD2 3.34Å; H194-F241 AromaticContact NE2-CE2 3.14Å; H194-F241 WeakPolarHBondContact NE2-CE2 3.41Å; H194-F241 AromaticContact NE2-CG 3.99Å; H194-F241 AromaticContact NE2-CZ 3.48Å; H194-F241 WeakPolarHBondContact NE2-CZ 3.49Å
195	Q	78.4	Confident	77.5	Confident	26 Å²	26	52.5 Å²	52.5	12%	0.121	30%	0.298	C	S	.	.	H	α-helix	trans	-57.2	-45.5	176.1	-83.3	179	-0.4	0	0	111.5	E191 V193 H197 S198 Y199 Y530 N538	E191-Q195 VanDerWaalsContact O-CB 3.32Å; E191-Q195 WeakPolarHBondContact O-CB 3.5Å; E191-Q195 WeakPolarHBondContact O-CG 3.28Å; E191-Q195 PolarHBondContact O-N 3.31Å; V193-Q195 VanDerWaalsContact C-N 3.34Å; V193-Q195 PolarHBondContact O-N 2.99Å; Q195-H197 PolarHBondContact O-N 2.87Å; Q195-S198 PolarHBondContact O-N 2.91Å; Q195-S198 PolarHBondContact O-OG 3.06Å; Q195-Y199 PolarHBondContact O-N 3.1Å; Q195-Y530 HydrophobicContact CB-CE1 3.94Å; Q195-Y530 VanDerWaalsContact CB-OH 3.31Å; Q195-Y530 WeakPolarHBondContact CB-OH 3.49Å; Q195-Y530 WeakPolarHBondContact O-CE1 3.4Å; Q195-Y530 PolarHBondContact O-OH 3.06Å; Q195-N538 PolarHBondContact OE1-ND2 2.92Å; Q195-N538 PolarHBondContact OE1-OD1 3.48Å
196	S	78.8	Confident	75.5	Confident	32 Å²	32	55.5 Å²	55.5	22%	0.224	32%	0.32	C	S	.	.	H	α-helix	trans	-59.5	-44.2	178.5	-172.2	0	0	0	0	112.4	S192 V193 H194 Y199 S200 Y530 S531	S192-S196 WeakPolarHBondContact O-CB 3.5Å; S192-S196 PolarHBondContact O-N 3.49Å; V193-S196 WeakPolarHBondContact O-CB 3.18Å; V193-S196 PolarHBondContact O-N 2.94Å; H194-S196 VanDerWaalsContact C-N 3.32Å; H194-S196 PolarHBondContact O-N 3.32Å; S196-Y199 PolarHBondContact O-N 3.44Å; S196-S200 PolarHBondContact O-N 3.19Å; S196-S200 VanDerWaalsContact O-N 3.08Å; S196-Y530 VanDerWaalsContact CA-CE1 3.42Å; S196-S531 PolarHBondContact OG-OG 3.02Å
197	H	76.9	Confident	73.2	Confident	116 Å²	116	58.4 Å²	58.4	54%	0.537	34%	0.339	S	S	.	.	H	α-helix	trans	-64.8	-42.7	176.1	-76.3	-67.6	0	0	0	112.8	V193 H194 Q195 Y199 S200 S201	V193-H197 PolarHBondContact O-CD2 3.43Å; V193-H197 PolarHBondContact O-N 3.47Å; H194-H197 PolarHBondContact O-N 2.87Å; Q195-H197 PolarHBondContact O-N 2.87Å; H197-Y199 VanDerWaalsContact C-N 3.34Å; H197-Y199 PolarHBondContact O-N 3.35Å; H197-S200 PolarHBondContact O-N 3.38Å; H197-S201 WeakPolarHBondContact O-CB 3.21Å; H197-S201 PolarHBondContact O-N 2.88Å
198	S	75.9	Confident	70.9	Confident	56 Å²	56	64.9 Å²	64.9	39%	0.392	37%	0.368	S	S	.	.	H	α-helix	trans	-62.2	-41.5	179.1	72.5	0	0	0	0	112.1	H194 Q195 S201 S202	H194-S198 PolarHBondContact O-N 3.49Å; Q195-S198 PolarHBondContact O-N 2.91Å; Q195-S198 PolarHBondContact O-OG 3.06Å; S198-S201 PolarHBondContact O-N 3.22Å; S198-S202 PolarHBondContact O-N 3.41Å; S198-S202 VanDerWaalsContact O-N 3.08Å
199	Y	73.8	Confident	68.7	Low	79 Å²	79	67.7 Å²	67.7	31%	0.31	40%	0.398	S	S	.	.	H	α-helix	trans	-64.5	-47.4	176.8	-176.8	-101.9	0	0	0	111.7	Q195 S196 H197 S201 S202 H203 V525 Y530	Q195-Y199 PolarHBondContact O-N 3.1Å; S196-Y199 PolarHBondContact O-N 3.44Å; H197-Y199 VanDerWaalsContact C-N 3.34Å; H197-Y199 PolarHBondContact O-N 3.35Å; Y199-S201 PolarHBondContact O-N 2.81Å; Y199-S202 PolarHBondContact O-N 3.34Å; Y199-H203 PolarHBondContact O-N 2.9Å; Y199-H203 VanDerWaalsContact O-N 3.13Å; Y199-V525 HydrophobicContact CE1-CG1 4.37Å; Y199-V525 HydrophobicContact CE2-CG1 4.4Å; Y199-Y530 HydrophobicContact CD1-CD1 4.4Å; Y199-Y530 AromaticContact CD1-CD2 3.57Å; Y199-Y530 HydrophobicContact CD1-CD2 3.57Å; Y199-Y530 HydrophobicContact CD1-CE2 4.25Å; Y199-Y530 AromaticContact CD1-CG 3.63Å; Y199-Y530 HydrophobicContact CD1-CG 3.63Å; Y199-Y530 AromaticContact CD2-CD2 3.46Å; Y199-Y530 HydrophobicContact CD2-CD2 3.46Å; Y199-Y530 VanDerWaalsContact CD2-CD2 3.46Å; Y199-Y530 AromaticContact CD2-CE2 3.49Å; Y199-Y530 HydrophobicContact CD2-CE2 3.49Å; Y199-Y530 VanDerWaalsContact CD2-CE2 3.49Å; Y199-Y530 HydrophobicContact CD2-CG 4.34Å; Y199-Y530 AromaticContact CE1-CD2 3.99Å; Y199-Y530 HydrophobicContact CE1-CD2 3.99Å; Y199-Y530 HydrophobicContact CE1-CG 4.19Å; Y199-Y530 AromaticContact CE2-CD2 3.89Å; Y199-Y530 HydrophobicContact CE2-CD2 3.89Å; Y199-Y530 HydrophobicContact CE2-CE2 4.24Å; Y199-Y530 HydrophobicContact CG-CD1 4.33Å; Y199-Y530 AromaticContact CG-CD2 3.28Å; Y199-Y530 HydrophobicContact CG-CD2 3.28Å; Y199-Y530 AromaticContact CG-CE2 3.49Å; Y199-Y530 HydrophobicContact CG-CE2 3.49Å; Y199-Y530 VanDerWaalsContact CG-CE2 3.49Å; Y199-Y530 AromaticContact CG-CG 3.72Å; Y199-Y530 HydrophobicContact CG-CG 3.72Å
200	S	75.4	Confident	66.6	Low	75 Å²	75	74.5 Å²	74.5	52%	0.524	43%	0.427	S	S	.	.	H	α-helix	trans	-61.4	-42.1	178.3	-175.5	0	0	0	0	112.3	S196 H197 S202 H203 S204	S196-S200 PolarHBondContact O-N 3.19Å; S196-S200 VanDerWaalsContact O-N 3.08Å; H197-S200 PolarHBondContact O-N 3.38Å; S200-S202 PolarHBondContact O-N 3.38Å; S200-H203 PolarHBondContact O-N 3.35Å; S200-S204 PolarHBondContact O-N 3.5Å; S200-S204 PolarHBondContact O-OG 3.04Å
201	S	72.4	Confident	64.3	Low	64 Å²	64	79.1 Å²	79.1	45%	0.448	45%	0.451	S	S	.	.	H	α-helix	trans	-66.5	-35.2	177.8	-173.8	0	0	0	0	113.2	H197 S198 Y199 H203 S204 N205	H197-S201 WeakPolarHBondContact O-CB 3.21Å; H197-S201 PolarHBondContact O-N 2.88Å; S198-S201 PolarHBondContact O-N 3.22Å; Y199-S201 PolarHBondContact O-N 2.81Å; S201-H203 VanDerWaalsContact C-N 3.31Å; S201-S204 PolarHBondContact O-OG 3.16Å; S201-S204 VanDerWaalsContact O-OG 3.13Å; S201-N205 PolarHBondContact O-N 2.93Å
202	S	68.2	Low	61.7	Low	81 Å²	81	82.5 Å²	82.5	57%	0.566	48%	0.481	S	S	*	.	H	α-helix	trans	-69.1	-33.2	176	-171.4	0	0	0	0	111.7	S198 Y199 S200	S198-S202 PolarHBondContact O-N 3.41Å; S198-S202 VanDerWaalsContact O-N 3.08Å; Y199-S202 PolarHBondContact O-N 3.34Å; S200-S202 PolarHBondContact O-N 3.38Å
203	H	63	Low	59.5	Low	106 Å²	106	86.6 Å²	86.6	49%	0.491	51%	0.51	S	S	.	.	H	α-helix	trans	-86.7	-24.4	-176.2	-142.5	-29.8	0	0	0	113.6	Y199 S200 S201 T206 S207	Y199-H203 PolarHBondContact O-N 2.9Å; Y199-H203 VanDerWaalsContact O-N 3.13Å; S200-H203 PolarHBondContact O-N 3.35Å; S201-H203 VanDerWaalsContact C-N 3.31Å; H203-T206 PolarHBondContact ND1-OG1 3.35Å; H203-T206 PolarHBondContact O-OG1 3.44Å; H203-S207 PolarHBondContact O-OG 2.84Å
204	S	57.2	Low	56.9	Low	45 Å²	45	92.1 Å²	92.1	32%	0.315	54%	0.537	S	S	.	.	H	α-helix	trans	-73.2	-35.8	172	61.6	0	0	0	0	112.4	S200 S201 T206 S207 H208	S200-S204 PolarHBondContact O-N 3.5Å; S200-S204 PolarHBondContact O-OG 3.04Å; S201-S204 PolarHBondContact O-OG 3.16Å; S201-S204 VanDerWaalsContact O-OG 3.13Å; S204-T206 PolarHBondContact O-N 3Å; S204-S207 WeakPolarHBondContact CA-OG 3.39Å; S204-S207 PolarHBondContact O-N 3.25Å; S204-S207 VanDerWaalsContact O-N 3.11Å; S204-S207 PolarHBondContact O-OG 3.5Å; S204-H208 PolarHBondContact O-N 3.42Å; S204-H208 VanDerWaalsContact O-N 3.16Å
205	N	51.1	Low	54.6	Low	134 Å²	134	97.8 Å²	97.8	72%	0.717	56%	0.564	S	S	*	*	T	Hydrogen-bonded Turn	trans	-65.6	-20.9	174.7	-81	-13.5	0	0	0	113.5	S201	S201-N205 PolarHBondContact O-N 2.93Å
206	T	48.7	Very low	52.1	Low	110 Å²	110	108.4 Å²	108.4	68%	0.675	60%	0.603	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.1	-10.7	174	50.1	0	0	0	0	113.8	H203 S204	H203-T206 PolarHBondContact ND1-OG1 3.35Å; H203-T206 PolarHBondContact O-OG1 3.44Å; S204-T206 PolarHBondContact O-N 3Å
207	S	42.5	Very low	49.9	Very low	76 Å²	76	112 Å²	112	53%	0.531	64%	0.635	S	S	.	*	T	Hydrogen-bonded Turn	trans	-114.2	-5.5	-175.2	45	0	0	0	0	114.9	H203 S204 G209	H203-S207 PolarHBondContact O-OG 2.84Å; S204-S207 WeakPolarHBondContact CA-OG 3.39Å; S204-S207 PolarHBondContact O-N 3.25Å; S204-S207 VanDerWaalsContact O-N 3.11Å; S204-S207 PolarHBondContact O-OG 3.5Å; S207-G209 PolarHBondContact O-N 2.88Å
208	H	40.9	Very low	47.5	Very low	138 Å²	138	109.9 Å²	109.9	64%	0.639	64%	0.644	S	S	*	*			trans	-97.6	67.2	174.5	-87	-74.1	0	0	0	113.9	S204	S204-H208 PolarHBondContact O-N 3.42Å; S204-H208 VanDerWaalsContact O-N 3.16Å
209	G	41.4	Very low	45.2	Very low	62 Å²	62	114.4 Å²	114.4	64%	0.639	66%	0.664	S	S	*	*	S	Bend	trans	-109.8	96.4	142.2	0	0	0	0	0	107.8	S207	S207-G209 PolarHBondContact O-N 2.88Å
210	H	40.6	Very low	43.7	Very low	180 Å²	180	116.8 Å²	116.8	83%	0.833	69%	0.689	S	S	*	*	S	Bend	trans	76.7	97	178.7	-59.4	-83.7	0	0	0	118
211	L	36.3	Very low	41.8	Very low	148 Å²	148	119.7 Å²	119.7	78%	0.775	70%	0.703	S	S	*	*				168.5	130.1	117.9	-89.5	155.2	0	0	0	112.1
212	A	30	Very low	40.2	Very low	82 Å²	82	120.7 Å²	120.7	68%	0.678	72%	0.724	S	S	*	*			trans	56.8	103.2	162.6	0	0	0	0	0	117.4
213	S	35.2	Very low	38.8	Very low	104 Å²	104	119.6 Å²	119.6	73%	0.727	73%	0.725	S	S	*	*				39.2	86.9	65.6	-171.1	0	0	0	0	112.7
214	D	27.2	Very low	38.2	Very low	167 Å²	167	121.8 Å²	121.8	89%	0.893	74%	0.74	S	S	*	*			trans	-119.2	103.5	154.1	-140	8.4	0	0	0	108.7	R216	D214-R216 PolarHBondContact O-N 2.9Å
215	Q	32.2	Very low	37.9	Very low	172 Å²	172	123.8 Å²	123.8	80%	0.804	75%	0.754	S	S	*	*			trans	-66.5	119.2	172.5	-80.3	167.3	-20.8	0	0	109.1
216	R	27.1	Very low	38.4	Very low	250 Å²	250	120.8 Å²	120.8	94%	0.943	74%	0.743	S	S	*	*			trans	-111.6	103.7	140.7	-84.9	-173.9	-173.2	160.4	4.7	108.8	D214 G218	D214-R216 PolarHBondContact O-N 2.9Å; R216-G218 PolarHBondContact O-N 3.47Å
217	A	32.7	Very low	39.2	Very low	108 Å²	108	121.3 Å²	121.3	89%	0.893	74%	0.741	S	S	*	*			trans	-66.6	121.6	166.7	0	0	0	0	0	109.9
218	G	26.6	Very low	40.5	Very low	71 Å²	71	119 Å²	119	73%	0.732	72%	0.724	S	S	*	*			trans	-163.9	91.6	166.2	0	0	0	0	0	108.7	R216	R216-G218 PolarHBondContact O-N 3.47Å
219	N	27.2	Very low	41.9	Very low	150 Å²	150	117.2 Å²	117.2	80%	0.802	73%	0.727	S	S	*	*			trans	39.6	121.9	168.1	-77.1	-3.6	0	0	0	120.8	V221	N219-V221 PolarHBondContact O-N 3.31Å
220	P	41.6	Very low	43.8	Very low	129 Å²	129	118.4 Å²	118.4	84%	0.838	72%	0.722	S	S	*	*			trans	-90.1	80.3	170.5	36	-28.3	0	0	0	110.4
221	V	36.8	Very low	45.8	Very low	137 Å²	137	112.9 Å²	112.9	83%	0.83	71%	0.708	S	S	*	*			trans	-142.5	96.8	167.1	-175.3	0	0	0	0	109.2	N219	N219-V221 PolarHBondContact O-N 3.31Å
222	G	37.9	Very low	48.1	Very low	85 Å²	85	109.7 Å²	109.7	88%	0.876	69%	0.694	S	S	*	*	S	Bend	trans	96.5	109.5	161.9	0	0	0	0	0	116.7
223	G	38.7	Very low	50.6	Low	57 Å²	57	106 Å²	106	59%	0.588	66%	0.664	S	S	*	*			trans	125.3	64.4	143	0	0	0	0	0	118.8	S225	G223-S225 PolarHBondContact O-N 3.49Å
224	D	50	Low	53	Low	152 Å²	152	106.3 Å²	106.3	81%	0.813	65%	0.654	S	S	*	*			trans	-65.4	17	150.4	-90.7	-24.6	0	0	0	112.5	C226	D224-C226 PolarHBondContact O-N 2.96Å
225	S	50.3	Low	55.8	Low	87 Å²	87	103.3 Å²	103.3	61%	0.608	64%	0.637	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.9	-1	-165.4	49.9	0	0	0	0	115.2	G223	G223-S225 PolarHBondContact O-N 3.49Å
226	C	63.3	Low	58.5	Low	71 Å²	71	97.7 Å²	97.7	48%	0.48	61%	0.61	S	S	.	*	T	Hydrogen-bonded Turn	trans	-121.4	28.9	-177	-53.6	0	0	0	0	113.6	C131 D224	C131-C226 HydrophobicContact CB-CB 3.85Å; C131-C226 WeakPolarHBondContact CB-SG 3.4Å; C131-C226 WeakPolarHBondContact SG-CB 3.43Å; C131-C226 CovalentContact SG-SG 2.04Å; C131-C226 PolarHBondContact SG-SG 3.17Å; D224-C226 PolarHBondContact O-N 2.96Å
227	L	64.6	Low	61.3	Low	122 Å²	122	88.5 Å²	88.5	64%	0.639	58%	0.577	S	S	*	*	S	Bend	trans	-104.4	134.7	175.3	-89.4	146.5	0	0	0	111.4	S229	L227-S229 PolarHBondContact O-N 3.37Å
228	C	70.3	Confident	63.7	Low	27 Å²	27	90.4 Å²	90.4	18%	0.182	57%	0.568	C	S	.	*			trans	-70.8	69.3	176.3	-168.1	0	0	0	0	111.6	F128 C233	F128-C228 HydrophobicContact CE1-CB 4.47Å; F128-C228 HydrophobicContact CE2-CB 4.48Å; F128-C228 HydrophobicContact CZ-CB 3.62Å; C228-C233 HydrophobicContact CB-CB 4.31Å; C228-C233 WeakPolarHBondContact CB-SG 3.34Å; C228-C233 WeakPolarHBondContact SG-CB 3.33Å; C228-C233 CovalentContact SG-SG 2.04Å; C228-C233 PolarHBondContact SG-SG 3.32Å
229	S	69.8	Low	66.5	Low	100 Å²	100	87.8 Å²	87.8	70%	0.699	54%	0.541	S	S	*	.			trans	-91.9	-20.3	-176.2	74.7	0	0	0	0	113.7	L227	L227-S229 PolarHBondContact O-N 3.37Å
230	T	81.7	Confident	69.3	Low	87 Å²	87	80.8 Å²	80.8	53%	0.534	50%	0.503	S	S	.	.	S	Bend	trans	-79.8	138	-176.3	-55.4	0	0	0	0	110.8	V232 C233 Q234	T230-V232 HydrophobicContact CG2-CB 4.14Å; T230-V232 HydrophobicContact CG2-CG2 4.32Å; T230-V232 PolarHBondContact O-N 2.96Å; T230-V232 VanDerWaalsContact O-N 3.13Å; T230-C233 WeakPolarHBondContact O-CB 3.47Å; T230-C233 PolarHBondContact O-N 3.19Å; T230-Q234 PolarHBondContact O-N 3.06Å
231	A	82.5	Confident	71.3	Confident	65 Å²	65	76.6 Å²	76.6	54%	0.537	47%	0.472	S	S	.	.	H	α-helix	trans	-52.5	-37.2	177.7	0	0	0	0	0	113	C233 Q234 I235	A231-C233 PolarHBondContact O-N 3.47Å; A231-Q234 PolarHBondContact O-N 3.39Å; A231-I235 WeakPolarHBondContact O-CD1 3.37Å; A231-I235 VanDerWaalsContact O-CG1 3.27Å; A231-I235 WeakPolarHBondContact O-CG1 3.33Å; A231-I235 PolarHBondContact O-N 3.02Å
232	V	83.4	Confident	73.5	Confident	80 Å²	80	75.7 Å²	75.7	49%	0.485	45%	0.454	S	S	.	.	H	α-helix	trans	-62.5	-40.8	176.4	178.9	0	0	0	0	112	T230 I235 F236	T230-V232 HydrophobicContact CG2-CB 4.14Å; T230-V232 HydrophobicContact CG2-CG2 4.32Å; T230-V232 PolarHBondContact O-N 2.96Å; T230-V232 VanDerWaalsContact O-N 3.13Å; V232-I235 PolarHBondContact O-N 3.25Å; V232-F236 HydrophobicContact CG1-CD2 3.71Å; V232-F236 HydrophobicContact CG1-CE2 3.37Å; V232-F236 HydrophobicContact CG1-CZ 4.35Å; V232-F236 WeakPolarHBondContact O-CD2 3.36Å; V232-F236 PolarHBondContact O-N 3.26Å
233	C	83.6	Confident	75.9	Confident	5 Å²	5	72.7 Å²	72.7	3%	0.034	42%	0.418	C	S	.	.	H	α-helix	trans	-65.6	-41.9	177.8	177.6	0	0	0	0	111.4	F128 C228 T230 A231 F236 Q237	F128-C233 WeakPolarHBondContact CE2-SG 3.17Å; F128-C233 WeakPolarHBondContact CZ-SG 3.46Å; C228-C233 HydrophobicContact CB-CB 4.31Å; C228-C233 WeakPolarHBondContact CB-SG 3.34Å; C228-C233 WeakPolarHBondContact SG-CB 3.33Å; C228-C233 CovalentContact SG-SG 2.04Å; C228-C233 PolarHBondContact SG-SG 3.32Å; T230-C233 WeakPolarHBondContact O-CB 3.47Å; T230-C233 PolarHBondContact O-N 3.19Å; A231-C233 PolarHBondContact O-N 3.47Å; C233-F236 PolarHBondContact O-N 2.84Å; C233-Q237 WeakPolarHBondContact O-CB 3.37Å; C233-Q237 PolarHBondContact O-N 3.28Å
234	Q	84.5	Confident	78	Confident	111 Å²	111	70.2 Å²	70.2	52%	0.519	39%	0.391	S	S	.	.	H	α-helix	trans	-65	-41.1	177.1	-66.7	-174.3	-15.3	0	0	112.3	T230 A231 F236 Q237 Q238	T230-Q234 PolarHBondContact O-N 3.06Å; A231-Q234 PolarHBondContact O-N 3.39Å; Q234-F236 VanDerWaalsContact C-N 3.33Å; Q234-F236 PolarHBondContact O-N 3.22Å; Q234-Q237 PolarHBondContact O-N 3.07Å; Q234-Q238 WeakPolarHBondContact O-CB 3.5Å; Q234-Q238 PolarHBondContact O-N 3.48Å
235	I	87.3	Confident	79.7	Confident	104 Å²	104	63.6 Å²	63.6	53%	0.533	36%	0.356	S	S	.	.	H	α-helix	trans	-61.2	-44.4	174.6	-68.5	163.8	0	0	0	110.4	A231 V232 Q238 G239	A231-I235 WeakPolarHBondContact O-CD1 3.37Å; A231-I235 VanDerWaalsContact O-CG1 3.27Å; A231-I235 WeakPolarHBondContact O-CG1 3.33Å; A231-I235 PolarHBondContact O-N 3.02Å; V232-I235 PolarHBondContact O-N 3.25Å; I235-Q238 PolarHBondContact O-N 3.47Å; I235-G239 PolarHBondContact O-N 2.89Å
236	F	88.9	Confident	81.5	Confident	54 Å²	54	60 Å²	60	24%	0.237	33%	0.33	C	S	.	.	H	α-helix	trans	-64	-43.4	177.8	-77.2	-51.3	0	0	0	112.7	F120 V232 C233 Q234 Y240	F120-F236 HydrophobicContact CB-CD1 4.45Å; F120-F236 AromaticContact CD1-CD1 3.76Å; F120-F236 HydrophobicContact CD1-CD1 3.76Å; F120-F236 HydrophobicContact CD1-CE1 4.48Å; F120-F236 HydrophobicContact CE1-CD1 4.31Å; F120-F236 HydrophobicContact CG-CD1 4.3Å; V232-F236 HydrophobicContact CG1-CD2 3.71Å; V232-F236 HydrophobicContact CG1-CE2 3.37Å; V232-F236 HydrophobicContact CG1-CZ 4.35Å; V232-F236 WeakPolarHBondContact O-CD2 3.36Å; V232-F236 PolarHBondContact O-N 3.26Å; C233-F236 PolarHBondContact O-N 2.84Å; Q234-F236 VanDerWaalsContact C-N 3.33Å; Q234-F236 PolarHBondContact O-N 3.22Å; F236-Y240 VanDerWaalsContact O-CB 3.3Å; F236-Y240 WeakPolarHBondContact O-CB 3.41Å; F236-Y240 PolarHBondContact O-N 2.96Å
237	Q	84.8	Confident	82.8	Confident	57 Å²	57	56.9 Å²	56.9	27%	0.266	31%	0.308	S	S	.	.	H	α-helix	trans	-59.8	-49.6	176.7	-171.8	-178.7	-6.3	0	0	111.3	Y124 C233 Q234 Y240 F241	Y124-Q237 HydrophobicContact CD2-CB 3.83Å; Y124-Q237 HydrophobicContact CD2-CG 4.36Å; Y124-Q237 HydrophobicContact CE2-CB 3.83Å; Y124-Q237 HydrophobicContact CE2-CG 3.95Å; C233-Q237 WeakPolarHBondContact O-CB 3.37Å; C233-Q237 PolarHBondContact O-N 3.28Å; Q234-Q237 PolarHBondContact O-N 3.07Å; Q237-Y240 PolarHBondContact O-N 3.44Å; Q237-F241 HydrophobicContact CG-CD2 3.9Å; Q237-F241 HydrophobicContact CG-CE2 3.56Å; Q237-F241 WeakPolarHBondContact O-CD2 3.34Å; Q237-F241 PolarHBondContact O-N 3.5Å
238	Q	84	Confident	84	Confident	148 Å²	148	51.1 Å²	51.1	69%	0.692	28%	0.278	S	S	*	.	H	α-helix	trans	-65.2	-43.4	-178.6	-170.4	174.1	9.5	0	0	112.1	Q234 I235 F241 Y242	Q234-Q238 WeakPolarHBondContact O-CB 3.5Å; Q234-Q238 PolarHBondContact O-N 3.48Å; I235-Q238 PolarHBondContact O-N 3.47Å; Q238-F241 PolarHBondContact O-N 3.36Å; Q238-Y242 WeakPolarHBondContact O-CB 3.47Å; Q238-Y242 PolarHBondContact O-N 3.2Å
239	G	85.9	Confident	84.9	Confident	16 Å²	16	50 Å²	50	17%	0.165	27%	0.27	C	S	.	.	H	α-helix	trans	-64.9	-38.4	177.7	0	0	0	0	0	113.2	I235 L243	I235-G239 PolarHBondContact O-N 2.89Å; G239-L243 WeakPolarHBondContact O-CG 3.36Å; G239-L243 PolarHBondContact O-N 3.11Å
240	Y	85.4	Confident	86	Confident	3 Å²	3	45.3 Å²	45.3	1%	0.012	24%	0.237	C	C	.	.	H	α-helix	trans	-58.4	-52.2	174.1	163.6	-123	0	0	0	112	M117 K121 D190 F236 Q237 Y242 L243 Y244	M117-Y240 HydrophobicContact CG-CD2 3.9Å; M117-Y240 HydrophobicContact CG-CE2 4.39Å; M117-Y240 HydrophobicContact SD-CD2 4.4Å; M117-Y240 HydrophobicContact SD-CE2 4.32Å; K121-Y240 HydrophobicContact CB-CD2 3.86Å; K121-Y240 HydrophobicContact CB-CE2 4.17Å; K121-Y240 HydrophobicContact CB-CG 4.47Å; K121-Y240 HydrophobicContact CD-CD2 4.13Å; K121-Y240 HydrophobicContact CD-CE2 3.53Å; K121-Y240 WeakPolarHBondContact CE-OH 3.21Å; K121-Y240 HydrophobicContact CG-CD2 4.1Å; K121-Y240 HydrophobicContact CG-CE2 3.94Å; K121-Y240 PolarHBondContact NZ-OH 3.23Å; D190-Y240 PolarHBondContact OD2-OH 3.3Å; F236-Y240 VanDerWaalsContact O-CB 3.3Å; F236-Y240 WeakPolarHBondContact O-CB 3.41Å; F236-Y240 PolarHBondContact O-N 2.96Å; Q237-Y240 PolarHBondContact O-N 3.44Å; Y240-Y242 PolarHBondContact O-N 3.44Å; Y240-L243 PolarHBondContact O-N 2.86Å; Y240-Y244 HydrophobicContact CD2-CD2 4.2Å; Y240-Y244 AromaticContact CE2-CD2 3.51Å; Y240-Y244 HydrophobicContact CE2-CD2 3.51Å; Y240-Y244 AromaticContact CE2-CE2 3.51Å; Y240-Y244 HydrophobicContact CE2-CE2 3.51Å; Y240-Y244 AromaticContact CZ-CD2 3.79Å; Y240-Y244 AromaticContact CZ-CE2 3.52Å; Y240-Y244 PolarHBondContact O-N 3.04Å; Y240-Y244 WeakPolarHBondContact OH-CE2 3.39Å
241	F	83.3	Confident	86.6	Confident	41 Å²	41	41.2 Å²	41.2	18%	0.18	21%	0.212	C	C	.	.	H	α-helix	trans	-69.7	-31.2	-177.9	-71	-60.9	0	0	0	113.4	H194 Q237 Q238 Y244	H194-F241 HydrophobicContact CB-CD1 4.18Å; H194-F241 HydrophobicContact CB-CE1 3.52Å; H194-F241 HydrophobicContact CB-CZ 3.94Å; H194-F241 AromaticContact CD2-CD2 3.91Å; H194-F241 AromaticContact CD2-CE1 3.48Å; H194-F241 VanDerWaalsContact CD2-CE1 3.48Å; H194-F241 WeakPolarHBondContact CD2-CE1 3.32Å; H194-F241 AromaticContact CD2-CE2 3.27Å; H194-F241 WeakPolarHBondContact CD2-CE2 3.39Å; H194-F241 AromaticContact CD2-CZ 3.03Å; H194-F241 WeakPolarHBondContact CD2-CZ 3.47Å; H194-F241 AromaticContact CE1-CD1 3.89Å; H194-F241 AromaticContact CE1-CD2 3.48Å; H194-F241 VanDerWaalsContact CE1-CD2 3.48Å; H194-F241 WeakPolarHBondContact CE1-CD2 3.3Å; H194-F241 AromaticContact CE1-CE2 3.67Å; H194-F241 AromaticContact CE1-CG 3.62Å; H194-F241 AromaticContact CE1-CZ 3.96Å; H194-F241 AromaticContact CG-CD1 3.65Å; H194-F241 AromaticContact CG-CE1 3.21Å; H194-F241 AromaticContact CG-CE2 3.85Å; H194-F241 AromaticContact CG-CZ 3.34Å; H194-F241 AromaticContact ND1-CD1 3.53Å; H194-F241 AromaticContact ND1-CD2 3.99Å; H194-F241 AromaticContact ND1-CE1 3.63Å; H194-F241 AromaticContact ND1-CG 3.75Å; H194-F241 AromaticContact ND1-CZ 3.92Å; H194-F241 AromaticContact NE2-CD2 3.42Å; H194-F241 WeakPolarHBondContact NE2-CD2 3.34Å; H194-F241 AromaticContact NE2-CE2 3.14Å; H194-F241 WeakPolarHBondContact NE2-CE2 3.41Å; H194-F241 AromaticContact NE2-CG 3.99Å; H194-F241 AromaticContact NE2-CZ 3.48Å; H194-F241 WeakPolarHBondContact NE2-CZ 3.49Å; Q237-F241 HydrophobicContact CG-CD2 3.9Å; Q237-F241 HydrophobicContact CG-CE2 3.56Å; Q237-F241 WeakPolarHBondContact O-CD2 3.34Å; Q237-F241 PolarHBondContact O-N 3.5Å; Q238-F241 PolarHBondContact O-N 3.36Å; F241-Y244 WeakPolarHBondContact O-CB 3.42Å
242	Y	83.6	Confident	86.9	Confident	117 Å²	117	38.7 Å²	38.7	46%	0.459	19%	0.189	S	C	.	.	H	α-helix	trans	-67.4	-38.5	175.7	-174.7	-100.1	0	0	0	112.6	Q238 Y240 P245 F513	Q238-Y242 WeakPolarHBondContact O-CB 3.47Å; Q238-Y242 PolarHBondContact O-N 3.2Å; Y240-Y242 PolarHBondContact O-N 3.44Å; Y242-P245 WeakPolarHBondContact O-CD 3.45Å; Y242-F513 PolarHBondContact OH-O 3.39Å
243	L	87.9	Confident	87.2	Confident	23 Å²	23	35 Å²	35	12%	0.12	17%	0.167	C	C	.	.	H	α-helix	trans	-86.9	-8.8	-176.5	-67.4	170.4	0	0	0	114.2	I116 M117 F120 G239 Y240 P245 F246	I116-L243 HydrophobicContact CB-CD1 4.12Å; I116-L243 HydrophobicContact CG2-CD1 3.53Å; M117-L243 HydrophobicContact CB-CB 3.73Å; M117-L243 HydrophobicContact CB-CD1 4.34Å; M117-L243 HydrophobicContact CG-CB 3.98Å; F120-L243 HydrophobicContact CD2-CD1 4.08Å; F120-L243 HydrophobicContact CE2-CD1 4.35Å; G239-L243 WeakPolarHBondContact O-CG 3.36Å; G239-L243 PolarHBondContact O-N 3.11Å; Y240-L243 PolarHBondContact O-N 2.86Å; L243-P245 VanDerWaalsContact C-N 3.33Å; L243-F246 HydrophobicContact CB-CD2 4.27Å; L243-F246 HydrophobicContact CD2-CD2 3.73Å; L243-F246 HydrophobicContact CD2-CE2 3.78Å; L243-F246 WeakPolarHBondContact O-CB 3.25Å; L243-F246 WeakPolarHBondContact O-CD2 3.47Å; L243-F246 PolarHBondContact O-N 3.24Å; L243-F246 VanDerWaalsContact O-N 3.09Å
244	Y	83.4	Confident	87.7	Confident	5 Å²	5	34.7 Å²	34.7	2%	0.02	17%	0.165	C	C	.	.	H	α-helix	trans	-47	-43.1	178.7	-148	-96.5	0	0	0	116.2	M117 A187 D190 E191 Y240 F241 F246 N247 I248	M117-Y244 HydrophobicContact SD-CD2 4Å; M117-Y244 HydrophobicContact SD-CE2 4.49Å; A187-Y244 VanDerWaalsContact C-CE1 3.42Å; A187-Y244 WeakPolarHBondContact CA-OH 3.4Å; A187-Y244 HydrophobicContact CB-CE1 3.65Å; A187-Y244 WeakPolarHBondContact O-CE1 3.36Å; A187-Y244 PolarHBondContact O-OH 2.62Å; D190-Y244 WeakPolarHBondContact CB-OH 3.41Å; D190-Y244 PolarHBondContact OD2-OH 3.43Å; E191-Y244 HydrophobicContact CB-CD1 3.75Å; E191-Y244 HydrophobicContact CB-CE1 3.63Å; E191-Y244 HydrophobicContact CG-CD1 4.14Å; Y240-Y244 HydrophobicContact CD2-CD2 4.2Å; Y240-Y244 AromaticContact CE2-CD2 3.51Å; Y240-Y244 HydrophobicContact CE2-CD2 3.51Å; Y240-Y244 AromaticContact CE2-CE2 3.51Å; Y240-Y244 HydrophobicContact CE2-CE2 3.51Å; Y240-Y244 AromaticContact CZ-CD2 3.79Å; Y240-Y244 AromaticContact CZ-CE2 3.52Å; Y240-Y244 PolarHBondContact O-N 3.04Å; Y240-Y244 WeakPolarHBondContact OH-CE2 3.39Å; F241-Y244 WeakPolarHBondContact O-CB 3.42Å; Y244-F246 PolarHBondContact O-N 2.93Å; Y244-N247 PolarHBondContact O-N 3.41Å; Y244-N247 VanDerWaalsContact O-N 3.15Å; Y244-I248 HydrophobicContact CD1-CD1 3.88Å; Y244-I248 HydrophobicContact CD1-CG1 4.35Å; Y244-I248 HydrophobicContact CE1-CD1 4.07Å; Y244-I248 HydrophobicContact CE1-CG1 4.41Å; Y244-I248 PolarHBondContact O-N 3.36Å
245	P	85.1	Confident	88	Confident	13 Å²	13	29.8 Å²	29.8	8%	0.084	14%	0.143	C	C	.	.	H	α-helix	trans	-65.7	-27	-176.9	-20.4	36.5	0	0	0	112.1	Y242 L243 N247 I248 E249	Y242-P245 WeakPolarHBondContact O-CD 3.45Å; L243-P245 VanDerWaalsContact C-N 3.33Å; P245-N247 VanDerWaalsContact C-N 3.35Å; P245-N247 PolarHBondContact O-N 2.97Å; P245-I248 WeakPolarHBondContact O-CB 3.07Å; P245-I248 PolarHBondContact O-N 3.25Å; P245-E249 WeakPolarHBondContact O-CG 3.36Å; P245-E249 PolarHBondContact O-N 3.43Å
246	F	88	Confident	88	Confident	11 Å²	11	25.9 Å²	25.9	5%	0.048	12%	0.124	C	C	.	.	H	α-helix	trans	-70.1	-31.9	178.2	-57.4	-64.8	0	0	0	112.5	F110 C113 L243 Y244 E249 Y250 F513	F110-F246 HydrophobicContact CD1-CB 4.33Å; F110-F246 AromaticContact CD1-CD1 3.82Å; F110-F246 HydrophobicContact CD1-CD1 3.82Å; F110-F246 AromaticContact CE1-CD1 3.9Å; F110-F246 HydrophobicContact CE1-CD1 3.9Å; C113-F246 HydrophobicContact CB-CB 3.53Å; C113-F246 HydrophobicContact CB-CD1 4.32Å; C113-F246 HydrophobicContact CB-CD2 3.94Å; C113-F246 HydrophobicContact CB-CG 3.67Å; L243-F246 HydrophobicContact CB-CD2 4.27Å; L243-F246 HydrophobicContact CD2-CD2 3.73Å; L243-F246 HydrophobicContact CD2-CE2 3.78Å; L243-F246 WeakPolarHBondContact O-CB 3.25Å; L243-F246 WeakPolarHBondContact O-CD2 3.47Å; L243-F246 PolarHBondContact O-N 3.24Å; L243-F246 VanDerWaalsContact O-N 3.09Å; Y244-F246 PolarHBondContact O-N 2.93Å; F246-E249 PolarHBondContact O-N 2.95Å; F246-Y250 WeakPolarHBondContact O-CB 3.2Å; F246-Y250 PolarHBondContact O-N 3.04Å; F246-F513 HydrophobicContact CZ-CD1 4.11Å; F246-F513 HydrophobicContact CZ-CE1 4.01Å; F246-F513 HydrophobicContact CZ-CZ 4.47Å
247	N	91	Very high	88	Confident	5 Å²	5	23.5 Å²	23.5	3%	0.027	11%	0.114	C	C	.	.	H	α-helix	trans	-67.6	-40.7	173.2	-176.5	27.2	0	0	0	111.9	T114 M117 Y244 P245 Y250 S251	T114-N247 HydrophobicContact CG2-CB 3.96Å; T114-N247 WeakPolarHBondContact CG2-OD1 3.11Å; T114-N247 WeakPolarHBondContact OG1-CA 3.22Å; M117-N247 HydrophobicContact CE-CB 3.82Å; M117-N247 HydrophobicContact SD-CB 3.71Å; Y244-N247 PolarHBondContact O-N 3.41Å; Y244-N247 VanDerWaalsContact O-N 3.15Å; P245-N247 VanDerWaalsContact C-N 3.35Å; P245-N247 PolarHBondContact O-N 2.97Å; N247-Y250 PolarHBondContact O-N 2.87Å; N247-S251 WeakPolarHBondContact O-CB 3.5Å; N247-S251 PolarHBondContact O-N 2.93Å; N247-S251 PolarHBondContact O-OG 3.4Å
248	I	89.5	Confident	88.4	Confident	1 Å²	1	20.8 Å²	20.8	1%	0.005	10%	0.101	C	C	.	.	H	α-helix	trans	-59.6	-49.2	174.6	-65.4	176.8	0	0	0	109.9	A187 V188 E191 Y244 P245 S251 L252 P542	A187-I248 HydrophobicContact CB-CD1 4.41Å; A187-I248 HydrophobicContact CB-CG1 3.76Å; V188-I248 HydrophobicContact CG2-CD1 4.04Å; V188-I248 HydrophobicContact CG2-CG1 4.47Å; V188-I248 HydrophobicContact CG2-CG2 4.36Å; E191-I248 WeakPolarHBondContact OE2-CD1 3.38Å; Y244-I248 HydrophobicContact CD1-CD1 3.88Å; Y244-I248 HydrophobicContact CD1-CG1 4.35Å; Y244-I248 HydrophobicContact CE1-CD1 4.07Å; Y244-I248 HydrophobicContact CE1-CG1 4.41Å; Y244-I248 PolarHBondContact O-N 3.36Å; P245-I248 WeakPolarHBondContact O-CB 3.07Å; P245-I248 PolarHBondContact O-N 3.25Å; I248-S251 PolarHBondContact O-N 3.42Å; I248-L252 PolarHBondContact O-N 3.25Å; I248-P542 HydrophobicContact CG2-CB 3.49Å; I248-P542 VanDerWaalsContact CG2-CB 3.49Å; I248-P542 HydrophobicContact CG2-CG 3.37Å
249	E	88.8	Confident	88.7	Confident	4 Å²	4	17.4 Å²	17.4	2%	0.019	8%	0.082	C	C	.	.	H	α-helix	trans	-62.7	-47.3	176.9	-70.7	-55.7	136.2	0	0	112.4	F110 P245 F246 S251 L252 F253 P542 I545	F110-E249 HydrophobicContact CD1-CB 3.86Å; F110-E249 HydrophobicContact CD2-CB 4.34Å; F110-E249 HydrophobicContact CE1-CB 3.82Å; F110-E249 HydrophobicContact CE1-CG 4.1Å; F110-E249 HydrophobicContact CE2-CB 4.32Å; F110-E249 HydrophobicContact CG-CB 4.13Å; F110-E249 HydrophobicContact CZ-CB 4.05Å; F110-E249 HydrophobicContact CZ-CG 4.29Å; P245-E249 WeakPolarHBondContact O-CG 3.36Å; P245-E249 PolarHBondContact O-N 3.43Å; F246-E249 PolarHBondContact O-N 2.95Å; E249-S251 VanDerWaalsContact C-N 3.25Å; E249-S251 PolarHBondContact O-N 3.13Å; E249-L252 PolarHBondContact O-N 2.99Å; E249-L252 VanDerWaalsContact O-N 3.13Å; E249-F253 WeakPolarHBondContact O-CD2 3.14Å; E249-F253 PolarHBondContact O-N 2.74Å; E249-P542 VanDerWaalsContact OE1-CA 3.24Å; E249-P542 WeakPolarHBondContact OE1-CA 3.44Å; E249-P542 WeakPolarHBondContact OE1-CB 3.08Å; E249-I545 VanDerWaalsContact CD-CG2 3.43Å; E249-I545 HydrophobicContact CG-CG2 3.97Å; E249-I545 VanDerWaalsContact OE1-CB 3.28Å; E249-I545 WeakPolarHBondContact OE1-CB 3.48Å; E249-I545 WeakPolarHBondContact OE1-CG2 3.18Å
250	Y	93.3	Very high	88.7	Confident	1 Å²	1	17.2 Å²	17.2	0%	0.004	8%	0.078	C	C	.	.	H	α-helix	trans	-51.7	-47.9	177.4	176	-96.4	0	0	0	111.4	L107 F110 V147 T151 F246 N247 L252 F253 A254	L107-Y250 HydrophobicContact CD1-CD2 4.1Å; L107-Y250 HydrophobicContact CD1-CE2 3.67Å; L107-Y250 HydrophobicContact CG-CE2 4.2Å; F110-Y250 HydrophobicContact CB-CD2 4.33Å; V147-Y250 HydrophobicContact CB-CE1 4.46Å; V147-Y250 HydrophobicContact CG1-CE1 4.18Å; V147-Y250 HydrophobicContact CG1-CE2 4.18Å; V147-Y250 HydrophobicContact CG2-CD1 4.4Å; V147-Y250 HydrophobicContact CG2-CE1 3.94Å; V147-Y250 PolarHBondContact O-OH 3.42Å; T151-Y250 PolarHBondContact N-OH 3.32Å; T151-Y250 WeakPolarHBondContact OG1-CE2 3.36Å; T151-Y250 PolarHBondContact OG1-OH 3.17Å; F246-Y250 WeakPolarHBondContact O-CB 3.2Å; F246-Y250 PolarHBondContact O-N 3.04Å; N247-Y250 PolarHBondContact O-N 2.87Å; Y250-L252 PolarHBondContact O-N 2.87Å; Y250-F253 PolarHBondContact O-N 2.93Å; Y250-A254 HydrophobicContact CE1-CB 4.38Å; Y250-A254 VanDerWaalsContact O-CB 3.26Å; Y250-A254 WeakPolarHBondContact O-CB 3.49Å; Y250-A254 PolarHBondContact O-N 3Å
251	S	93.9	Very high	88.8	Confident	1 Å²	1	17.4 Å²	17.4	1%	0.007	8%	0.079	C	C	.	.	H	α-helix	trans	-62.5	-39.3	-178.4	-62.4	0	0	0	0	112.4	N180 N247 I248 E249 S255	N180-S251 WeakPolarHBondContact O-CB 3.5Å; N247-S251 WeakPolarHBondContact O-CB 3.5Å; N247-S251 PolarHBondContact O-N 2.93Å; N247-S251 PolarHBondContact O-OG 3.4Å; I248-S251 PolarHBondContact O-N 3.42Å; E249-S251 VanDerWaalsContact C-N 3.25Å; E249-S251 PolarHBondContact O-N 3.13Å; S251-S255 VanDerWaalsContact O-CB 3.29Å; S251-S255 WeakPolarHBondContact O-CB 3.18Å; S251-S255 PolarHBondContact O-N 3.28Å; S251-S255 PolarHBondContact O-OG 2.8Å
252	L	89.9	Confident	89.1	Confident	12 Å²	12	16.3 Å²	16.3	6%	0.063	7%	0.074	C	C	.	.	H	α-helix	trans	-70.7	-42.4	176.1	-69.1	177.8	0	0	0	112.5	W184 I248 E249 Y250 S255 T256 P542 F543	W184-L252 HydrophobicContact CD2-CD2 4.15Å; W184-L252 HydrophobicContact CG-CD2 4.11Å; W184-L252 HydrophobicContact CG-CG 4.33Å; I248-L252 PolarHBondContact O-N 3.25Å; E249-L252 PolarHBondContact O-N 2.99Å; E249-L252 VanDerWaalsContact O-N 3.13Å; Y250-L252 PolarHBondContact O-N 2.87Å; L252-S255 PolarHBondContact O-N 2.93Å; L252-T256 PolarHBondContact O-N 3.45Å; L252-T256 PolarHBondContact O-OG1 3.42Å; L252-P542 HydrophobicContact CD1-CB 3.82Å; L252-F543 HydrophobicContact CD2-CE1 4.47Å
253	F	88.6	Confident	89.1	Confident	2 Å²	2	13.7 Å²	13.7	1%	0.009	7%	0.065	C	C	.	.	H	α-helix	trans	-60.7	-48.6	175.3	-93.5	-97.4	0	0	0	111.4	L103 F110 E249 Y250 S255 T256 M257 F546 M549	L103-F253 HydrophobicContact CD1-CD1 3.69Å; L103-F253 HydrophobicContact CD1-CE1 3.78Å; F110-F253 HydrophobicContact CD2-CD2 4.02Å; F110-F253 HydrophobicContact CD2-CE2 4.09Å; F110-F253 HydrophobicContact CD2-CG 4.42Å; F110-F253 AromaticContact CE2-CD2 3.9Å; F110-F253 HydrophobicContact CE2-CD2 3.9Å; F110-F253 AromaticContact CE2-CE2 3.49Å; F110-F253 HydrophobicContact CE2-CE2 3.49Å; F110-F253 VanDerWaalsContact CE2-CE2 3.49Å; F110-F253 AromaticContact CE2-CZ 3.87Å; F110-F253 HydrophobicContact CE2-CZ 3.87Å; F110-F253 HydrophobicContact CZ-CE2 4.31Å; E249-F253 WeakPolarHBondContact O-CD2 3.14Å; E249-F253 PolarHBondContact O-N 2.74Å; Y250-F253 PolarHBondContact O-N 2.93Å; F253-S255 PolarHBondContact O-N 3.3Å; F253-T256 WeakPolarHBondContact O-CB 3.34Å; F253-T256 PolarHBondContact O-N 3.41Å; F253-M257 WeakPolarHBondContact O-CG 3.43Å; F253-M257 PolarHBondContact O-N 2.71Å; F253-F546 HydrophobicContact CD1-CE2 4.44Å; F253-F546 AromaticContact CD2-CD2 3.79Å; F253-F546 HydrophobicContact CD2-CD2 3.79Å; F253-F546 HydrophobicContact CD2-CE2 4.12Å; F253-F546 HydrophobicContact CE1-CE2 4.42Å; F253-F546 AromaticContact CE2-CD2 3.58Å; F253-F546 HydrophobicContact CE2-CD2 3.58Å; F253-F546 HydrophobicContact CE2-CE2 4.1Å; F253-F546 HydrophobicContact CG-CD2 4.41Å; F253-F546 HydrophobicContact CG-CE2 4.29Å; F253-F546 HydrophobicContact CZ-CD2 4.05Å; F253-F546 HydrophobicContact CZ-CE2 4.25Å; F253-M549 HydrophobicContact CZ-CB 3.93Å; F253-M549 HydrophobicContact CZ-CE 4.34Å; F253-M549 HydrophobicContact CZ-CG 4.27Å
254	A	93.7	Very high	88.9	Confident	0 Å²	0	12.7 Å²	12.7	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-64.4	-41.9	179.9	0	0	0	0	0	111.7	L107 L154 N180 Y250 T256 M257 L258	L107-A254 HydrophobicContact CD1-CB 4.03Å; L154-A254 HydrophobicContact CD1-CB 3.79Å; N180-A254 WeakPolarHBondContact OD1-CB 3.36Å; Y250-A254 HydrophobicContact CE1-CB 4.38Å; Y250-A254 VanDerWaalsContact O-CB 3.26Å; Y250-A254 WeakPolarHBondContact O-CB 3.49Å; Y250-A254 PolarHBondContact O-N 3Å; A254-T256 VanDerWaalsContact C-N 3.32Å; A254-T256 PolarHBondContact O-N 3.43Å; A254-M257 PolarHBondContact O-N 3.33Å; A254-L258 WeakPolarHBondContact O-CB 3.25Å; A254-L258 WeakPolarHBondContact O-CD1 3.39Å; A254-L258 WeakPolarHBondContact O-CG 3.26Å; A254-L258 PolarHBondContact O-N 3.35Å
255	S	92.8	Very high	89	Confident	8 Å²	8	12.6 Å²	12.6	6%	0.056	6%	0.059	C	C	.	.	H	α-helix	trans	-57.4	-44.1	173.5	-63.8	0	0	0	0	112.1	L177 N180 S251 L252 F253 L258 Y259	L177-S255 VanDerWaalsContact CD1-O 3.31Å; L177-S255 WeakPolarHBondContact CD1-O 3.28Å; N180-S255 WeakPolarHBondContact CB-OG 3.41Å; S251-S255 VanDerWaalsContact O-CB 3.29Å; S251-S255 WeakPolarHBondContact O-CB 3.18Å; S251-S255 PolarHBondContact O-N 3.28Å; S251-S255 PolarHBondContact O-OG 2.8Å; L252-S255 PolarHBondContact O-N 2.93Å; F253-S255 PolarHBondContact O-N 3.3Å; S255-L258 PolarHBondContact O-N 2.86Å; S255-Y259 WeakPolarHBondContact O-CB 3.43Å; S255-Y259 PolarHBondContact O-N 2.89Å
256	T	87.3	Confident	88.7	Confident	21 Å²	21	12.4 Å²	12.4	13%	0.129	6%	0.06	C	C	.	.	H	α-helix	trans	-62.9	-47.1	177.9	-61	0	0	0	0	111.6	L252 F253 A254 L258 Y259 V260 L371 F546	L252-T256 PolarHBondContact O-N 3.45Å; L252-T256 PolarHBondContact O-OG1 3.42Å; F253-T256 WeakPolarHBondContact O-CB 3.34Å; F253-T256 PolarHBondContact O-N 3.41Å; A254-T256 VanDerWaalsContact C-N 3.32Å; A254-T256 PolarHBondContact O-N 3.43Å; T256-L258 PolarHBondContact O-N 3.09Å; T256-Y259 WeakPolarHBondContact O-CB 3.32Å; T256-Y259 PolarHBondContact O-N 3.17Å; T256-V260 WeakPolarHBondContact O-CG2 3.47Å; T256-V260 PolarHBondContact O-N 3.29Å; T256-L371 HydrophobicContact CG2-CD1 3.45Å; T256-L371 VanDerWaalsContact CG2-CD1 3.45Å; T256-L371 HydrophobicContact CG2-CD2 3.81Å; T256-L371 HydrophobicContact CG2-CG 4.29Å; T256-F546 HydrophobicContact CG2-CZ 4.14Å
257	M	88.3	Confident	88.1	Confident	4 Å²	4	14 Å²	14	2%	0.02	7%	0.066	C	C	.	.	H	α-helix	trans	-62.7	-42.6	178	-71.3	-177	70.5	0	0	112.1	L103 R104 L107 L154 A158 F253 A254 Y259 V260 M261	L103-M257 HydrophobicContact CD2-CE 4.49Å; L103-M257 HydrophobicContact CD2-CG 3.51Å; L103-M257 HydrophobicContact CD2-SD 4.05Å; L103-M257 HydrophobicContact CG-CG 3.91Å; L103-M257 HydrophobicContact CG-SD 3.91Å; R104-M257 HydrophobicContact CG-CE 4.3Å; L107-M257 HydrophobicContact CB-SD 4.22Å; L107-M257 HydrophobicContact CD1-SD 4.3Å; L107-M257 HydrophobicContact CD2-CE 4.33Å; L107-M257 HydrophobicContact CD2-SD 3.93Å; L107-M257 HydrophobicContact CG-SD 4.38Å; L154-M257 HydrophobicContact CB-CE 4.09Å; L154-M257 HydrophobicContact CD1-CB 4.37Å; L154-M257 HydrophobicContact CD2-CB 4.08Å; A158-M257 HydrophobicContact CB-CE 3.46Å; A158-M257 VanDerWaalsContact CB-CE 3.46Å; F253-M257 WeakPolarHBondContact O-CG 3.43Å; F253-M257 PolarHBondContact O-N 2.71Å; A254-M257 PolarHBondContact O-N 3.33Å; M257-Y259 VanDerWaalsContact C-N 3.29Å; M257-Y259 PolarHBondContact O-N 3.3Å; M257-V260 PolarHBondContact O-N 3.46Å; M257-M261 WeakPolarHBondContact O-CG 3.28Å; M257-M261 PolarHBondContact O-N 2.98Å
258	L	93.3	Very high	87.1	Confident	0 Å²	0	20.2 Å²	20.2	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-61.4	-38.5	175.7	-71.5	165.3	0	0	0	111.8	F153 L154 L173 T176 L177 A254 S255 T256 M261 W262	F153-L258 HydrophobicContact CE1-CD2 3.81Å; L154-L258 HydrophobicContact CD2-CD2 3.84Å; L154-L258 HydrophobicContact CD2-CG 4.02Å; L173-L258 HydrophobicContact CD2-CD2 3.74Å; T176-L258 HydrophobicContact CG2-CD1 3.61Å; T176-L258 HydrophobicContact CG2-CD2 4.16Å; L177-L258 HydrophobicContact CB-CB 4.1Å; L177-L258 HydrophobicContact CB-CD1 4.25Å; L177-L258 HydrophobicContact CD1-CB 4.43Å; A254-L258 WeakPolarHBondContact O-CB 3.25Å; A254-L258 WeakPolarHBondContact O-CD1 3.39Å; A254-L258 WeakPolarHBondContact O-CG 3.26Å; A254-L258 PolarHBondContact O-N 3.35Å; S255-L258 PolarHBondContact O-N 2.86Å; T256-L258 PolarHBondContact O-N 3.09Å; L258-M261 PolarHBondContact O-N 3.32Å; L258-W262 WeakPolarHBondContact O-CB 3.49Å; L258-W262 PolarHBondContact O-N 3.48Å
259	Y	90	Very high	85.9	Confident	77 Å²	77	22.7 Å²	22.7	30%	0.302	11%	0.105	S	C	.	.	H	α-helix	trans	-64.9	-43.7	175.9	-177	-89.4	0	0	0	112.2	M174 L177 S255 T256 M257 W262 K263 L367	M174-Y259 HydrophobicContact CE-CD2 4.22Å; L177-Y259 HydrophobicContact CD1-CD2 4.27Å; S255-Y259 WeakPolarHBondContact O-CB 3.43Å; S255-Y259 PolarHBondContact O-N 2.89Å; T256-Y259 WeakPolarHBondContact O-CB 3.32Å; T256-Y259 PolarHBondContact O-N 3.17Å; M257-Y259 VanDerWaalsContact C-N 3.29Å; M257-Y259 PolarHBondContact O-N 3.3Å; Y259-W262 HydrophobicContact CE2-CE3 4.46Å; Y259-W262 HydrophobicContact CE2-CZ3 4.34Å; Y259-W262 PolarHBondContact O-N 3.49Å; Y259-K263 HydrophobicContact CD1-CD 4.36Å; Y259-K263 HydrophobicContact CE1-CD 3.57Å; Y259-K263 VanDerWaalsContact CE1-CE 3.43Å; Y259-K263 HydrophobicContact CE1-CG 4.01Å; Y259-K263 VanDerWaalsContact CZ-CE 3.46Å; Y259-K263 PolarHBondContact O-N 2.92Å; Y259-K263 WeakPolarHBondContact OH-CE 3.36Å; Y259-K263 PolarHBondContact OH-NZ 3.43Å; Y259-L367 HydrophobicContact CD1-CD1 3.66Å; Y259-L367 HydrophobicContact CD1-CD2 3.63Å; Y259-L367 HydrophobicContact CD1-CG 4.29Å; Y259-L367 HydrophobicContact CE1-CD1 3.31Å; Y259-L367 HydrophobicContact CE1-CD2 3.81Å; Y259-L367 HydrophobicContact CE1-CG 4.17Å
260	V	85.3	Confident	84.1	Confident	13 Å²	13	27 Å²	27	8%	0.079	14%	0.142	C	C	.	.	H	α-helix	trans	-58.3	-49.6	173.9	176.2	0	0	0	0	110	A98 T256 M257 W262 K263 N264 L367	A98-V260 HydrophobicContact CB-CG1 3.96Å; T256-V260 WeakPolarHBondContact O-CG2 3.47Å; T256-V260 PolarHBondContact O-N 3.29Å; M257-V260 PolarHBondContact O-N 3.46Å; V260-W262 VanDerWaalsContact C-N 3.33Å; V260-W262 PolarHBondContact O-N 2.9Å; V260-K263 PolarHBondContact O-N 3.5Å; V260-N264 PolarHBondContact O-N 2.81Å; V260-N264 VanDerWaalsContact O-N 3.07Å; V260-L367 HydrophobicContact CB-CD2 4.33Å; V260-L367 HydrophobicContact CG2-CD2 3.46Å; V260-L367 VanDerWaalsContact CG2-CD2 3.46Å
261	M	87.7	Confident	81.6	Confident	6 Å²	6	32.4 Å²	32.4	3%	0.03	18%	0.18	C	C	.	.	H	α-helix	trans	-58.3	-44.3	177.6	-70.6	177.2	69	0	0	111.5	F153 L154 S157 L173 M257 L258 K263 N264 V265	F153-M261 HydrophobicContact CE1-CE 4Å; F153-M261 HydrophobicContact CE1-SD 4.33Å; F153-M261 HydrophobicContact CE2-CE 3.92Å; F153-M261 HydrophobicContact CZ-CE 3.38Å; F153-M261 HydrophobicContact CZ-SD 4.29Å; L154-M261 HydrophobicContact CD2-SD 3.63Å; S157-M261 VanDerWaalsContact O-CE 3.28Å; S157-M261 WeakPolarHBondContact O-CE 3.45Å; L173-M261 HydrophobicContact CD1-CB 4.17Å; L173-M261 HydrophobicContact CD2-CB 4.13Å; L173-M261 HydrophobicContact CD2-CE 4.19Å; M257-M261 WeakPolarHBondContact O-CG 3.28Å; M257-M261 PolarHBondContact O-N 2.98Å; L258-M261 PolarHBondContact O-N 3.32Å; M261-K263 VanDerWaalsContact C-N 3.35Å; M261-K263 PolarHBondContact O-N 3.41Å; M261-N264 WeakPolarHBondContact O-CB 3.24Å; M261-N264 PolarHBondContact O-N 3.39Å; M261-V265 WeakPolarHBondContact O-CG2 3.46Å; M261-V265 PolarHBondContact O-N 2.84Å
262	W	89.9	Confident	79.1	Confident	18 Å²	18	36.2 Å²	36.2	7%	0.068	21%	0.211	C	C	.	.	H	α-helix	trans	-62.3	-39.9	178.7	174.1	92.4	0	0	0	112.6	R29 S32 V33 L173 M174 L258 Y259 V260 N264 V265	R29-W262 HydrophobicContact CB-CZ2 4.48Å; R29-W262 HydrophobicContact CG-CH2 3.52Å; R29-W262 HydrophobicContact CG-CZ2 3.26Å; S32-W262 PolarHBondContact OG-NE1 3.45Å; V33-W262 HydrophobicContact CG2-CH2 3.94Å; V33-W262 HydrophobicContact CG2-CZ2 3.66Å; L173-W262 HydrophobicContact CB-CB 4.17Å; L173-W262 HydrophobicContact CD1-CB 4.1Å; M174-W262 HydrophobicContact CE-CB 3.69Å; M174-W262 HydrophobicContact CE-CD2 3.64Å; M174-W262 HydrophobicContact CE-CE3 4.09Å; M174-W262 HydrophobicContact CE-CG 3.45Å; M174-W262 VanDerWaalsContact CE-CG 3.45Å; M174-W262 HydrophobicContact CG-CD2 4.44Å; M174-W262 HydrophobicContact CG-CG 4.18Å; M174-W262 HydrophobicContact SD-CD2 4.43Å; M174-W262 HydrophobicContact SD-CG 4.49Å; L258-W262 WeakPolarHBondContact O-CB 3.49Å; L258-W262 PolarHBondContact O-N 3.48Å; Y259-W262 HydrophobicContact CE2-CE3 4.46Å; Y259-W262 HydrophobicContact CE2-CZ3 4.34Å; Y259-W262 PolarHBondContact O-N 3.49Å; V260-W262 VanDerWaalsContact C-N 3.33Å; V260-W262 PolarHBondContact O-N 2.9Å; W262-N264 VanDerWaalsContact C-N 3.26Å; W262-N264 PolarHBondContact O-N 3.07Å; W262-V265 PolarHBondContact O-N 3.29Å
263	K	84.5	Confident	76.7	Confident	62 Å²	62	40.8 Å²	40.8	27%	0.27	24%	0.242	S	C	.	.	H	α-helix	trans	-64.4	-31.7	173.6	-85.7	-166	166.4	165.6	0	112.6	Y259 V260 M261 V265	Y259-K263 HydrophobicContact CD1-CD 4.36Å; Y259-K263 HydrophobicContact CE1-CD 3.57Å; Y259-K263 VanDerWaalsContact CE1-CE 3.43Å; Y259-K263 HydrophobicContact CE1-CG 4.01Å; Y259-K263 VanDerWaalsContact CZ-CE 3.46Å; Y259-K263 PolarHBondContact O-N 2.92Å; Y259-K263 WeakPolarHBondContact OH-CE 3.36Å; Y259-K263 PolarHBondContact OH-NZ 3.43Å; V260-K263 PolarHBondContact O-N 3.5Å; M261-K263 VanDerWaalsContact C-N 3.35Å; M261-K263 PolarHBondContact O-N 3.41Å; K263-V265 VanDerWaalsContact C-N 3.34Å
264	N	83.1	Confident	74.3	Confident	3 Å²	3	44.1 Å²	44.1	2%	0.016	28%	0.277	C	S	.	.	H	α-helix	trans	-78.9	-12.7	179.6	-72.5	-13.9	0	0	0	113.9	D95 V260 M261 W262 G266 R267	D95-N264 PolarHBondContact OD2-ND2 2.99Å; V260-N264 PolarHBondContact O-N 2.81Å; V260-N264 VanDerWaalsContact O-N 3.07Å; M261-N264 WeakPolarHBondContact O-CB 3.24Å; M261-N264 PolarHBondContact O-N 3.39Å; W262-N264 VanDerWaalsContact C-N 3.26Å; W262-N264 PolarHBondContact O-N 3.07Å; N264-G266 PolarHBondContact O-N 2.93Å; N264-R267 WeakPolarHBondContact O-CB 3.33Å; N264-R267 PolarHBondContact O-N 3.41Å; N264-R267 PolarHBondContact OD1-NH1 2.92Å
265	V	86	Confident	71.4	Confident	2 Å²	2	51.7 Å²	51.7	1%	0.012	31%	0.312	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64	116.2	178.3	-179.7	0	0	0	0	112.1	L166 T169 R170 L173 M261 W262 K263	L166-V265 HydrophobicContact CB-CG1 4.39Å; L166-V265 HydrophobicContact CD2-CG1 3.55Å; T169-V265 HydrophobicContact CG2-CG1 4.49Å; T169-V265 HydrophobicContact CG2-CG2 3.93Å; R170-V265 HydrophobicContact CG-CB 4.15Å; R170-V265 HydrophobicContact CG-CG1 3.92Å; R170-V265 HydrophobicContact CG-CG2 4.5Å; R170-V265 PolarHBondContact NH2-O 3.16Å; L173-V265 HydrophobicContact CD1-CG2 3.63Å; M261-V265 WeakPolarHBondContact O-CG2 3.46Å; M261-V265 PolarHBondContact O-N 2.84Å; W262-V265 PolarHBondContact O-N 3.29Å; K263-V265 VanDerWaalsContact C-N 3.34Å
266	G	77.1	Confident	68.6	Low	9 Å²	9	56.4 Å²	56.4	9%	0.093	35%	0.345	C	S	.	.	T	Hydrogen-bonded Turn	trans	75.8	21.1	179.4	0	0	0	0	0	114.8	V162 N264	V162-G266 PolarHBondContact O-N 3.46Å; N264-G266 PolarHBondContact O-N 2.93Å
267	R	76.7	Confident	66.2	Low	46 Å²	46	63.3 Å²	63.3	17%	0.174	38%	0.376	C	S	.	.	P	Polyproline II helix	trans	-88	123.4	175.1	-167.3	177.9	79.1	174.2	7.4	110.4	D95 H163 N264 T364	D95-R267 IonicContact OD1-NH2 3.46Å; D95-R267 IonicContact OD2-CZ 3.23Å; D95-R267 IonicContact OD2-NH1 2.85Å; D95-R267 IonicContact OD2-NH2 2.88Å; D95-R267 PolarHBondContact OD2-NH2 3.33Å; H163-R267 PolarHBondContact CE1-O 3.02Å; H163-R267 PolarHBondContact NE2-O 3.31Å; N264-R267 WeakPolarHBondContact O-CB 3.33Å; N264-R267 PolarHBondContact O-N 3.41Å; N264-R267 PolarHBondContact OD1-NH1 2.92Å; R267-T364 PolarHBondContact NH1-OG1 2.81Å
268	F	69.7	Low	63.9	Low	134 Å²	134	69.2 Å²	69.2	59%	0.588	41%	0.412	S	S	*	.	P	Polyproline II helix	trans	-83	121.4	169.5	-64.2	-78.9	0	0	0	108.9	Y93 H163	Y93-F268 HydrophobicContact CE2-CD1 4.5Å; H163-F268 AromaticContact CD2-CE1 3.92Å; H163-F268 AromaticContact NE2-CD1 3.86Å; H163-F268 AromaticContact NE2-CE1 3.89Å
269	L	64.9	Low	61.7	Low	53 Å²	53	72.2 Å²	72.2	28%	0.277	43%	0.431	S	S	.	.	P	Polyproline II helix	trans	-92.4	123.2	166.4	-76.2	114.1	0	0	0	108	C161 S271	C161-L269 VanDerWaalsContact SG-CD1 3.57Å; L269-S271 PolarHBondContact O-N 3.23Å
270	A	49.8	Very low	59.4	Low	96 Å²	96	71.6 Å²	71.6	79%	0.793	44%	0.438	S	S	*	.	P	Polyproline II helix	trans	-62.5	128	163.2	0	0	0	0	0	107	A272	A270-A272 VanDerWaalsContact C-N 3.33Å; A270-A272 PolarHBondContact O-N 3.36Å
271	S	40.8	Very low	57.9	Low	114 Å²	114	76 Å²	76	80%	0.797	47%	0.467	S	S	*	.			trans	-61.1	94.7	178.5	-170.6	0	0	0	0	108.9	L269	L269-S271 PolarHBondContact O-N 3.23Å
272	A	42.4	Very low	56	Low	80 Å²	80	83 Å²	83	66%	0.661	50%	0.504	S	S	*	.			trans	-69.6	132.4	165.3	0	0	0	0	0	107.2	A270 G274	A270-A272 VanDerWaalsContact C-N 3.33Å; A270-A272 PolarHBondContact O-N 3.36Å; A272-G274 PolarHBondContact O-N 3.23Å; A272-G274 VanDerWaalsContact O-N 3.15Å
273	P	37.9	Very low	54.2	Low	108 Å²	108	84 Å²	84	70%	0.701	51%	0.513	S	S	*	.			trans	-56.4	122.9	173.4	-18.1	29.2	0	0	0	108.7	H275	P273-H275 PolarHBondContact O-N 3.27Å
274	G	38.1	Very low	52.7	Low	73 Å²	73	82.2 Å²	82.2	75%	0.753	51%	0.507	S	S	*	.			trans	-64.6	98.1	177.7	0	0	0	0	0	110.6	A272	A272-G274 PolarHBondContact O-N 3.23Å; A272-G274 VanDerWaalsContact O-N 3.15Å
275	H	33.1	Very low	51.3	Low	159 Å²	159	87.3 Å²	87.3	74%	0.736	53%	0.529	S	S	*	.			trans	-111.2	65.9	159	-70.7	-42.6	0	0	0	109	P273 H277	P273-H275 PolarHBondContact O-N 3.27Å; H275-H277 PolarHBondContact O-N 3.24Å; H275-H277 VanDerWaalsContact O-N 3.17Å
276	S	34.4	Very low	49.7	Very low	107 Å²	107	96.9 Å²	96.9	75%	0.748	57%	0.565	S	S	*	*			trans	-81.2	79	161	59.7	0	0	0	0	108.2	T278	S276-T278 VanDerWaalsContact C-N 3.29Å; S276-T278 PolarHBondContact O-N 3.05Å; S276-T278 VanDerWaalsContact O-N 3.09Å
277	H	36.7	Very low	48.9	Very low	166 Å²	166	100 Å²	100	77%	0.769	58%	0.577	S	S	*	*			trans	-71.3	96.9	157.1	-77.3	-76.5	0	0	0	106.5	H275 P279	H275-H277 PolarHBondContact O-N 3.24Å; H275-H277 VanDerWaalsContact O-N 3.17Å; H277-P279 WeakPolarHBondContact O-CD 3.4Å
278	T	40.2	Very low	48.2	Very low	127 Å²	127	98.3 Å²	98.3	78%	0.779	57%	0.572	S	S	*	*			trans	-67.5	110.5	161.6	24.7	0	0	0	0	107.1	S276 S280	S276-T278 VanDerWaalsContact C-N 3.29Å; S276-T278 PolarHBondContact O-N 3.05Å; S276-T278 VanDerWaalsContact O-N 3.09Å; T278-S280 PolarHBondContact O-N 3.29Å
279	P	47.1	Very low	48.1	Very low	63 Å²	63	96.7 Å²	96.7	41%	0.409	57%	0.565	S	S	.	*			trans	-62.4	140	171.1	26	-31.1	0	0	0	108.6	H277 L284	H277-P279 WeakPolarHBondContact O-CD 3.4Å; P279-L284 HydrophobicContact CG-CD1 4.4Å; P279-L284 HydrophobicContact CG-CD2 4.42Å; P279-L284 HydrophobicContact CG-CG 4.46Å
280	S	41.6	Very low	48.7	Very low	65 Å²	65	99 Å²	99	46%	0.455	57%	0.573	S	S	.	*			trans	-58.3	139	177.5	60.6	0	0	0	0	110.8	T278 L282 S283	T278-S280 PolarHBondContact O-N 3.29Å; S280-L282 PolarHBondContact O-N 3.43Å; S280-L282 VanDerWaalsContact O-N 3.09Å; S280-S283 PolarHBondContact O-N 2.93Å; S280-S283 PolarHBondContact O-OG 2.96Å; S280-S283 WeakPolarHBondContact OG-CB 3.37Å; S280-S283 PolarHBondContact OG-OG 3.46Å
281	P	53.2	Low	50.4	Low	104 Å²	104	97.7 Å²	97.7	68%	0.675	56%	0.562	S	S	*	*	H	α-helix	trans	-58.4	-27.9	-178.3	20	-30.7	0	0	0	113.1
282	L	48.5	Very low	52.6	Low	155 Å²	155	92.8 Å²	92.8	81%	0.812	53%	0.529	S	S	*	.	H	α-helix	trans	-74.3	-23.8	177	-95.5	123.7	0	0	0	114.5	S280	S280-L282 PolarHBondContact O-N 3.43Å; S280-L282 VanDerWaalsContact O-N 3.09Å
283	S	51.6	Low	54.8	Low	38 Å²	38	90 Å²	90	27%	0.266	50%	0.504	S	S	.	.	H	α-helix	trans	-82.5	-18.6	175.5	62	0	0	0	0	113.1	S280	S280-S283 PolarHBondContact O-N 2.93Å; S280-S283 PolarHBondContact O-OG 2.96Å; S280-S283 WeakPolarHBondContact OG-CB 3.37Å; S280-S283 PolarHBondContact OG-OG 3.46Å
284	L	53.2	Low	57.4	Low	24 Å²	24	89.6 Å²	89.6	13%	0.126	50%	0.499	C	S	.	.	H	α-helix	trans	-72.5	-34.6	-179	-81	164.9	0	0	0	113.1	P279 R286 Y559	P279-L284 HydrophobicContact CG-CD1 4.4Å; P279-L284 HydrophobicContact CG-CD2 4.42Å; P279-L284 HydrophobicContact CG-CG 4.46Å; L284-R286 VanDerWaalsContact C-N 3.34Å; L284-Y559 HydrophobicContact CB-CE1 4.31Å; L284-Y559 HydrophobicContact CD2-CE1 4.3Å; L284-Y559 PolarHBondContact O-OH 2.93Å; L284-Y559 VanDerWaalsContact O-OH 3.12Å
285	F	55.1	Low	60.1	Low	110 Å²	110	89.6 Å²	89.6	48%	0.482	48%	0.482	S	S	.	.	G	3₁₀ helix	trans	-79.3	-14.2	177.1	-92.6	-86.8	0	0	0	114	E287 T288 F290	F285-E287 PolarHBondContact O-N 3.38Å; F285-T288 PolarHBondContact O-OG1 3.38Å; F285-F290 AromaticContact CD1-CE1 3.75Å; F285-F290 HydrophobicContact CD1-CE1 3.75Å; F285-F290 HydrophobicContact CD1-CZ 4.13Å; F285-F290 HydrophobicContact CE1-CE1 4.28Å; F285-F290 WeakPolarHBondContact O-CZ 3.25Å
286	R	51.8	Low	63	Low	203 Å²	203	82 Å²	82	77%	0.766	45%	0.447	S	S	*	.	G	3₁₀ helix	trans	-76.1	-4	-171.6	-158.8	170.9	67.3	-162.7	1.2	114	L284	L284-R286 VanDerWaalsContact C-N 3.34Å
287	E	59.5	Low	65.8	Low	74 Å²	74	81.6 Å²	81.6	35%	0.346	44%	0.436	S	S	.	.	G	3₁₀ helix	trans	-129.6	16.5	-177	-61	-173.3	144.6	0	0	113.5	F285 R491 R494	F285-E287 PolarHBondContact O-N 3.38Å; E287-R491 HydrophobicContact CB-CG 4.2Å; E287-R491 VanDerWaalsContact O-CB 3.3Å; E287-R491 WeakPolarHBondContact O-CB 3.44Å; E287-R491 WeakPolarHBondContact O-CD 3.42Å; E287-R491 WeakPolarHBondContact O-CG 3.2Å; E287-R494 IonicContact OE2-CZ 3.82Å; E287-R494 IonicContact OE2-NH1 2.74Å; E287-R494 PolarHBondContact OE2-NH1 3.04Å; E287-R494 IonicContact OE2-NH2 2.8Å
288	T	62.4	Low	68.6	Low	11 Å²	11	78.3 Å²	78.3	7%	0.067	42%	0.423	C	S	.	.			trans	-90.9	140.4	178.8	-33	0	0	0	0	109	F285 F290 P293 D495 L498	F285-T288 PolarHBondContact O-OG1 3.38Å; T288-F290 WeakPolarHBondContact O-CD2 3.47Å; T288-F290 PolarHBondContact O-N 2.87Å; T288-P293 HydrophobicContact CG2-CG 4.08Å; T288-D495 WeakPolarHBondContact CA-OD1 3.29Å; T288-D495 WeakPolarHBondContact CG2-OD1 3.39Å; T288-L498 HydrophobicContact CG2-CD1 3.97Å
289	F	67.9	Low	71.3	Confident	100 Å²	100	73 Å²	73	44%	0.439	39%	0.39	S	S	.	.			trans	-72.4	-7.4	173	-71.5	-75.7	0	0	0	112	A291 W488 R491 D495	F289-A291 PolarHBondContact O-N 2.93Å; F289-W488 AromaticContact CE2-CD1 4Å; F289-W488 AromaticContact CZ-CD1 3.54Å; F289-W488 HydrophobicContact CZ-CG 4.48Å; F289-W488 AromaticContact CZ-NE1 3.97Å; F289-R491 HydrophobicContact CD2-CB 3.7Å; F289-R491 HydrophobicContact CE2-CB 3.28Å; F289-R491 HydrophobicContact CE2-CG 4.35Å; F289-R491 HydrophobicContact CZ-CB 4.02Å; F289-D495 WeakPolarHBondContact CB-OD2 3.02Å; F289-D495 PolarHBondContact N-OD1 3.43Å
290	F	78.3	Confident	73.6	Confident	103 Å²	103	72.1 Å²	72.1	45%	0.452	38%	0.38	S	S	.	.	S	Bend	trans	62.5	-11.1	-178.7	-69.6	-86.8	0	0	0	115.3	F285 T288 P293 V294 D495	F285-F290 AromaticContact CD1-CE1 3.75Å; F285-F290 HydrophobicContact CD1-CE1 3.75Å; F285-F290 HydrophobicContact CD1-CZ 4.13Å; F285-F290 HydrophobicContact CE1-CE1 4.28Å; F285-F290 WeakPolarHBondContact O-CZ 3.25Å; T288-F290 WeakPolarHBondContact O-CD2 3.47Å; T288-F290 PolarHBondContact O-N 2.87Å; F290-P293 WeakPolarHBondContact O-CD 3.37Å; F290-V294 WeakPolarHBondContact O-CB 3.36Å; F290-V294 WeakPolarHBondContact O-CG2 3.49Å; F290-V294 PolarHBondContact O-N 3.33Å; F290-V294 VanDerWaalsContact O-N 3.08Å; F290-D495 PolarHBondContact N-OD2 2.81Å
291	A	85	Confident	76.2	Confident	67 Å²	67	73 Å²	73	55%	0.554	38%	0.383	S	S	*	.	H	α-helix	trans	-62.5	-44.4	177.6	0	0	0	0	0	112.1	F289 L295 D495	F289-A291 PolarHBondContact O-N 2.93Å; A291-L295 WeakPolarHBondContact O-CB 3.31Å; A291-L295 PolarHBondContact O-N 2.98Å; A291-D495 PolarHBondContact N-OD2 3.36Å
292	G	87	Confident	78.3	Confident	11 Å²	11	71.6 Å²	71.6	11%	0.113	37%	0.368	C	S	.	.	H	α-helix	trans	-60.8	-55	177.9	0	0	0	0	0	113.1	V294 L295 G296 D495	G292-V294 PolarHBondContact O-N 3.46Å; G292-L295 PolarHBondContact O-N 2.83Å; G292-G296 PolarHBondContact O-N 2.82Å; G292-D495 PolarHBondContact N-OD2 3.22Å
293	P	88.9	Confident	80.5	Confident	21 Å²	21	64.2 Å²	64.2	14%	0.136	33%	0.33	C	S	.	.	H	α-helix	trans	-57.4	-41.5	176.2	-27.9	34.8	0	0	0	114.3	T288 F290 G296 L297 L498 L502	T288-P293 HydrophobicContact CG2-CG 4.08Å; F290-P293 WeakPolarHBondContact O-CD 3.37Å; P293-G296 PolarHBondContact O-N 2.87Å; P293-L297 WeakPolarHBondContact O-CB 3.14Å; P293-L297 PolarHBondContact O-N 3.31Å; P293-L498 HydrophobicContact CG-CB 3.9Å; P293-L498 HydrophobicContact CG-CD1 3.59Å; P293-L498 HydrophobicContact CG-CG 4.42Å; P293-L502 WeakPolarHBondContact O-CD1 3.46Å
294	V	92.8	Very high	82.5	Confident	100 Å²	100	65 Å²	65	61%	0.606	33%	0.331	S	S	*	.	H	α-helix	trans	-64.7	-46.5	179.1	169.7	0	0	0	0	111	F290 G292 G296 L297 L298	F290-V294 WeakPolarHBondContact O-CB 3.36Å; F290-V294 WeakPolarHBondContact O-CG2 3.49Å; F290-V294 PolarHBondContact O-N 3.33Å; F290-V294 VanDerWaalsContact O-N 3.08Å; G292-V294 PolarHBondContact O-N 3.46Å; V294-G296 VanDerWaalsContact C-N 3.35Å; V294-L297 PolarHBondContact O-N 2.83Å; V294-L298 WeakPolarHBondContact O-CB 3.48Å; V294-L298 PolarHBondContact O-N 2.91Å
295	L	93.4	Very high	84.5	Confident	74 Å²	74	66.2 Å²	66.2	39%	0.387	34%	0.344	S	S	.	.	H	α-helix	trans	-65.2	-39.5	177.2	-175.3	65	0	0	0	111.8	A291 G292 L298 L299 F499	A291-L295 WeakPolarHBondContact O-CB 3.31Å; A291-L295 PolarHBondContact O-N 2.98Å; G292-L295 PolarHBondContact O-N 2.83Å; L295-L298 HydrophobicContact CD1-CD2 4.49Å; L295-L298 PolarHBondContact O-N 3.17Å; L295-L299 PolarHBondContact O-N 3.47Å; L295-F499 HydrophobicContact CB-CD2 4.19Å; L295-F499 HydrophobicContact CB-CE2 4.33Å; L295-F499 HydrophobicContact CD2-CD2 4.1Å; L295-F499 HydrophobicContact CD2-CE2 3.7Å; L295-F499 HydrophobicContact CD2-CZ 4.44Å; L295-F499 HydrophobicContact CG-CD2 4.13Å; L295-F499 HydrophobicContact CG-CE2 3.77Å
296	G	94	Very high	86.4	Confident	0 Å²	0	61.6 Å²	61.6	0%	0	33%	0.325	C	S	.	.	H	α-helix	trans	-64.1	-41.1	176.1	0	0	0	0	0	112.2	G292 P293 V294 L299 F300	G292-G296 PolarHBondContact O-N 2.82Å; P293-G296 PolarHBondContact O-N 2.87Å; V294-G296 VanDerWaalsContact C-N 3.35Å; G296-L299 PolarHBondContact O-N 3.19Å; G296-F300 WeakPolarHBondContact O-CB 3.35Å; G296-F300 PolarHBondContact O-N 3.19Å
297	L	94.4	Very high	88.4	Confident	98 Å²	98	53.3 Å²	53.3	51%	0.513	29%	0.294	S	S	.	.	H	α-helix	trans	-66.4	-39.5	176.5	-176.5	65.4	0	0	0	111.4	P293 V294 F300 V301 L502	P293-L297 WeakPolarHBondContact O-CB 3.14Å; P293-L297 PolarHBondContact O-N 3.31Å; V294-L297 PolarHBondContact O-N 2.83Å; L297-F300 WeakPolarHBondContact O-CB 3.41Å; L297-F300 PolarHBondContact O-N 2.95Å; L297-V301 HydrophobicContact CD1-CG2 4.47Å; L297-V301 WeakPolarHBondContact O-CG2 3.42Å; L297-V301 PolarHBondContact O-N 3.29Å; L297-L502 HydrophobicContact CB-CD1 4.43Å
298	L	95.6	Very high	89.9	Confident	97 Å²	97	54.7 Å²	54.7	51%	0.508	30%	0.303	S	S	.	.	H	α-helix	trans	-59.3	-49.9	174.6	-179.6	66.1	0	0	0	111.2	V294 L295 F300 V301 I302	V294-L298 WeakPolarHBondContact O-CB 3.48Å; V294-L298 PolarHBondContact O-N 2.91Å; L295-L298 HydrophobicContact CD1-CD2 4.49Å; L295-L298 PolarHBondContact O-N 3.17Å; L298-F300 VanDerWaalsContact C-N 3.31Å; L298-F300 PolarHBondContact O-N 3.22Å; L298-V301 PolarHBondContact O-N 2.83Å; L298-I302 HydrophobicContact CD1-CD1 3.94Å; L298-I302 HydrophobicContact CD1-CG1 4.42Å; L298-I302 HydrophobicContact CG-CD1 3.87Å; L298-I302 VanDerWaalsContact O-CG1 3.27Å; L298-I302 WeakPolarHBondContact O-CG1 3.23Å; L298-I302 PolarHBondContact O-N 3.49Å
299	L	95.6	Very high	91.2	Very high	14 Å²	14	57.3 Å²	57.3	7%	0.073	32%	0.316	C	S	.	.	H	α-helix	trans	-64.1	-35.9	176.8	-72.7	179.7	0	0	0	112.4	L295 G296 G303 F331 L338 F499	L295-L299 PolarHBondContact O-N 3.47Å; G296-L299 PolarHBondContact O-N 3.19Å; L299-G303 PolarHBondContact O-N 3.14Å; L299-F331 HydrophobicContact CD2-CE2 4.37Å; L299-F331 WeakPolarHBondContact O-CZ 3.21Å; L299-L338 HydrophobicContact CD1-CD1 3.96Å; L299-F499 HydrophobicContact CD1-CE2 3.79Å; L299-F499 HydrophobicContact CD1-CZ 3.98Å
300	F	95.6	Very high	92.3	Very high	45 Å²	45	52.8 Å²	52.8	20%	0.197	30%	0.296	C	S	.	.	H	α-helix	trans	-61.4	-49.5	175.2	179	-91.5	0	0	0	111.6	G296 L297 L298 G303 L304 V505 I506 I509	G296-F300 WeakPolarHBondContact O-CB 3.35Å; G296-F300 PolarHBondContact O-N 3.19Å; L297-F300 WeakPolarHBondContact O-CB 3.41Å; L297-F300 PolarHBondContact O-N 2.95Å; L298-F300 VanDerWaalsContact C-N 3.31Å; L298-F300 PolarHBondContact O-N 3.22Å; F300-G303 PolarHBondContact O-N 3.28Å; F300-L304 HydrophobicContact CD1-CD1 3.95Å; F300-L304 HydrophobicContact CD1-CG 4.41Å; F300-L304 HydrophobicContact CE1-CD1 3.31Å; F300-L304 HydrophobicContact CE1-CG 4.04Å; F300-L304 HydrophobicContact CZ-CD1 3.74Å; F300-L304 HydrophobicContact CZ-CD2 4.47Å; F300-L304 HydrophobicContact CZ-CG 4.19Å; F300-L304 WeakPolarHBondContact O-CG 3.37Å; F300-L304 PolarHBondContact O-N 3.42Å; F300-V505 HydrophobicContact CD2-CG1 4.47Å; F300-V505 HydrophobicContact CE2-CB 4.46Å; F300-V505 HydrophobicContact CE2-CG1 3.83Å; F300-I506 HydrophobicContact CD2-CB 3.82Å; F300-I506 HydrophobicContact CE2-CB 4.41Å; F300-I509 HydrophobicContact CE2-CD1 3.87Å; F300-I509 HydrophobicContact CZ-CD1 4.16Å
301	V	96.4	Very high	92.8	Very high	85 Å²	85	50 Å²	50	52%	0.515	29%	0.285	S	S	.	.	H	α-helix	trans	-65.1	-44.7	179.3	173.3	0	0	0	0	111.5	L297 L298 G303 L304 A305	L297-V301 HydrophobicContact CD1-CG2 4.47Å; L297-V301 WeakPolarHBondContact O-CG2 3.42Å; L297-V301 PolarHBondContact O-N 3.29Å; L298-V301 PolarHBondContact O-N 2.83Å; V301-G303 VanDerWaalsContact C-N 3.31Å; V301-G303 PolarHBondContact O-N 2.82Å; V301-L304 PolarHBondContact O-N 3.2Å; V301-A305 PolarHBondContact O-N 3.15Å
302	I	96.4	Very high	92.9	Very high	74 Å²	74	51.6 Å²	51.6	38%	0.379	29%	0.287	S	S	.	.	H	α-helix	trans	-61.3	-43.8	176.1	-66.7	169.5	0	0	0	110.1	L298 L304 A305 V306 F331	L298-I302 HydrophobicContact CD1-CD1 3.94Å; L298-I302 HydrophobicContact CD1-CG1 4.42Å; L298-I302 HydrophobicContact CG-CD1 3.87Å; L298-I302 VanDerWaalsContact O-CG1 3.27Å; L298-I302 WeakPolarHBondContact O-CG1 3.23Å; L298-I302 PolarHBondContact O-N 3.49Å; I302-L304 PolarHBondContact O-N 3.07Å; I302-A305 WeakPolarHBondContact O-CB 3.47Å; I302-A305 PolarHBondContact O-N 2.92Å; I302-V306 HydrophobicContact CG2-CG2 4.41Å; I302-V306 WeakPolarHBondContact O-CG2 3.42Å; I302-V306 PolarHBondContact O-N 3.4Å; I302-F331 HydrophobicContact CB-CE2 4.14Å; I302-F331 HydrophobicContact CG2-CD2 3.76Å; I302-F331 HydrophobicContact CG2-CE2 3.74Å
303	G	95.3	Very high	92.8	Very high	0 Å²	0	53.2 Å²	53.2	0%	0	29%	0.291	C	S	.	.	H	α-helix	trans	-64.3	-38.4	178.3	0	0	0	0	0	112.8	L299 F300 V301 A305 V306 F307 M510	L299-G303 PolarHBondContact O-N 3.14Å; F300-G303 PolarHBondContact O-N 3.28Å; V301-G303 VanDerWaalsContact C-N 3.31Å; V301-G303 PolarHBondContact O-N 2.82Å; G303-A305 VanDerWaalsContact C-N 3.32Å; G303-A305 PolarHBondContact O-N 3.08Å; G303-V306 PolarHBondContact O-N 3.46Å; G303-F307 WeakPolarHBondContact O-CB 3.08Å; G303-F307 PolarHBondContact O-N 3.42Å; G303-M510 WeakPolarHBondContact O-CE 3.43Å
304	L	94.8	Very high	92.4	Very high	55 Å²	55	54.2 Å²	54.2	29%	0.288	30%	0.297	S	S	.	.	H	α-helix	trans	-61.5	-41.8	172.8	-76.6	-179.4	0	0	0	111.6	F300 V301 I302 F307 I308 I506 I509	F300-L304 HydrophobicContact CD1-CD1 3.95Å; F300-L304 HydrophobicContact CD1-CG 4.41Å; F300-L304 HydrophobicContact CE1-CD1 3.31Å; F300-L304 HydrophobicContact CE1-CG 4.04Å; F300-L304 HydrophobicContact CZ-CD1 3.74Å; F300-L304 HydrophobicContact CZ-CD2 4.47Å; F300-L304 HydrophobicContact CZ-CG 4.19Å; F300-L304 WeakPolarHBondContact O-CG 3.37Å; F300-L304 PolarHBondContact O-N 3.42Å; V301-L304 PolarHBondContact O-N 3.2Å; I302-L304 PolarHBondContact O-N 3.07Å; L304-F307 PolarHBondContact O-N 3.44Å; L304-I308 VanDerWaalsContact O-CG1 3.29Å; L304-I308 WeakPolarHBondContact O-CG1 3.36Å; L304-I308 PolarHBondContact O-N 3.38Å; L304-I506 HydrophobicContact CD2-CD1 3.81Å; L304-I506 HydrophobicContact CG-CD1 3.93Å; L304-I509 HydrophobicContact CD2-CG2 4.37Å
305	A	94.9	Very high	91.5	Very high	48 Å²	48	53.9 Å²	53.9	40%	0.397	30%	0.299	S	S	.	.	H	α-helix	trans	-62.9	-44.3	175.3	0	0	0	0	0	111.6	V301 I302 G303 F307 I308 I309	V301-A305 PolarHBondContact O-N 3.15Å; I302-A305 WeakPolarHBondContact O-CB 3.47Å; I302-A305 PolarHBondContact O-N 2.92Å; G303-A305 VanDerWaalsContact C-N 3.32Å; G303-A305 PolarHBondContact O-N 3.08Å; A305-F307 PolarHBondContact O-N 2.86Å; A305-I308 PolarHBondContact O-N 3.27Å; A305-I309 WeakPolarHBondContact O-CB 3.37Å; A305-I309 WeakPolarHBondContact O-CD1 3.46Å; A305-I309 WeakPolarHBondContact O-CG1 3.23Å; A305-I309 PolarHBondContact O-N 3.01Å
306	V	94.4	Very high	90.2	Very high	13 Å²	13	53.1 Å²	53.1	8%	0.079	31%	0.309	C	S	.	.	H	α-helix	trans	-62	-42	176.4	170	0	0	0	0	111.6	I302 G303 I309 Y310 I327 Y328 F331	I302-V306 HydrophobicContact CG2-CG2 4.41Å; I302-V306 WeakPolarHBondContact O-CG2 3.42Å; I302-V306 PolarHBondContact O-N 3.4Å; G303-V306 PolarHBondContact O-N 3.46Å; V306-I309 PolarHBondContact O-N 3Å; V306-Y310 WeakPolarHBondContact O-CB 3.38Å; V306-Y310 PolarHBondContact O-N 3.48Å; V306-I327 HydrophobicContact CG1-CG2 4.1Å; V306-I327 HydrophobicContact CG2-CG2 4Å; V306-Y328 HydrophobicContact CG1-CD2 4.44Å; V306-F331 HydrophobicContact CB-CG 4.47Å; V306-F331 HydrophobicContact CG1-CB 4.21Å; V306-F331 HydrophobicContact CG1-CD1 4.49Å; V306-F331 HydrophobicContact CG1-CG 4.43Å; V306-F331 HydrophobicContact CG2-CB 4.11Å; V306-F331 HydrophobicContact CG2-CD2 4.3Å; V306-F331 HydrophobicContact CG2-CG 4.13Å
307	F	93.4	Very high	88.7	Confident	30 Å²	30	56.7 Å²	56.7	13%	0.132	35%	0.346	C	S	.	.	H	α-helix	trans	-59.2	-49.9	175.7	170.6	-111.4	0	0	0	111.7	G303 L304 A305 I309 Y310 E311 M510 F513 A515	G303-F307 WeakPolarHBondContact O-CB 3.08Å; G303-F307 PolarHBondContact O-N 3.42Å; L304-F307 PolarHBondContact O-N 3.44Å; A305-F307 PolarHBondContact O-N 2.86Å; F307-I309 VanDerWaalsContact C-N 3.32Å; F307-I309 PolarHBondContact O-N 3.18Å; F307-Y310 WeakPolarHBondContact O-CB 3.44Å; F307-Y310 PolarHBondContact O-N 3.47Å; F307-E311 HydrophobicContact CD2-CG 4.19Å; F307-E311 HydrophobicContact CE1-CG 4.43Å; F307-E311 HydrophobicContact CE2-CG 3.63Å; F307-E311 HydrophobicContact CZ-CG 3.76Å; F307-E311 PolarHBondContact O-N 3.35Å; F307-M510 HydrophobicContact CB-CE 4.34Å; F307-M510 HydrophobicContact CB-CG 4.18Å; F307-M510 HydrophobicContact CD2-CB 4.48Å; F307-M510 HydrophobicContact CD2-CG 4.28Å; F307-F513 HydrophobicContact CE1-CB 4.39Å; F307-F513 HydrophobicContact CE2-CB 4.26Å; F307-F513 HydrophobicContact CZ-CB 3.63Å; F307-A515 HydrophobicContact CD2-CB 3.7Å; F307-A515 HydrophobicContact CE2-CB 3.73Å
308	I	91.6	Very high	87.1	Confident	103 Å²	103	54.7 Å²	54.7	53%	0.528	35%	0.349	S	S	.	.	H	α-helix	trans	-60.8	-43.3	178.1	-66.5	165.2	0	0	0	110.7	L304 A305 Y310 E311 V312	L304-I308 VanDerWaalsContact O-CG1 3.29Å; L304-I308 WeakPolarHBondContact O-CG1 3.36Å; L304-I308 PolarHBondContact O-N 3.38Å; A305-I308 PolarHBondContact O-N 3.27Å; I308-Y310 VanDerWaalsContact C-N 3.34Å; I308-Y310 PolarHBondContact O-N 2.85Å; I308-E311 PolarHBondContact O-N 3.05Å; I308-V312 HydrophobicContact CG2-CG2 4.32Å; I308-V312 WeakPolarHBondContact O-CB 3.27Å; I308-V312 VanDerWaalsContact O-CG2 3.25Å; I308-V312 WeakPolarHBondContact O-CG2 3.39Å; I308-V312 PolarHBondContact O-N 3.47Å
309	I	90.6	Very high	85.7	Confident	66 Å²	66	53.6 Å²	53.6	34%	0.338	36%	0.361	S	S	.	.	H	α-helix	trans	-61.3	-44	177.1	-70.2	165.3	0	0	0	110.8	A305 V306 F307 Q313	A305-I309 WeakPolarHBondContact O-CB 3.37Å; A305-I309 WeakPolarHBondContact O-CD1 3.46Å; A305-I309 WeakPolarHBondContact O-CG1 3.23Å; A305-I309 PolarHBondContact O-N 3.01Å; V306-I309 PolarHBondContact O-N 3Å; F307-I309 VanDerWaalsContact C-N 3.32Å; F307-I309 PolarHBondContact O-N 3.18Å; I309-Q313 HydrophobicContact CG2-CG 4.34Å; I309-Q313 VanDerWaalsContact O-CB 3.29Å; I309-Q313 WeakPolarHBondContact O-CB 3.44Å; I309-Q313 VanDerWaalsContact O-CG 3.32Å; I309-Q313 WeakPolarHBondContact O-CG 3.4Å; I309-Q313 PolarHBondContact O-N 3.45Å
310	Y	90.8	Very high	85.1	Confident	5 Å²	5	60.4 Å²	60.4	2%	0.02	39%	0.386	C	S	.	.	H	α-helix	trans	-60	-54	178.3	174.9	-89.6	0	0	0	111	V306 F307 I308 V312 Q313 V314 A324 L325 Y328 A515 R516 P517 S520	V306-Y310 WeakPolarHBondContact O-CB 3.38Å; V306-Y310 PolarHBondContact O-N 3.48Å; F307-Y310 WeakPolarHBondContact O-CB 3.44Å; F307-Y310 PolarHBondContact O-N 3.47Å; I308-Y310 VanDerWaalsContact C-N 3.34Å; I308-Y310 PolarHBondContact O-N 2.85Å; Y310-V312 PolarHBondContact O-N 2.74Å; Y310-Q313 PolarHBondContact O-N 2.92Å; Y310-V314 HydrophobicContact CD1-CG2 4.42Å; Y310-V314 HydrophobicContact CD2-CG2 3.88Å; Y310-V314 HydrophobicContact CE1-CG2 4.19Å; Y310-V314 HydrophobicContact CE2-CG2 3.63Å; Y310-V314 HydrophobicContact CG-CG2 4.27Å; Y310-V314 WeakPolarHBondContact O-CB 3.2Å; Y310-V314 VanDerWaalsContact O-CG2 3.27Å; Y310-V314 WeakPolarHBondContact O-CG2 3.49Å; Y310-V314 PolarHBondContact O-N 3.01Å; Y310-A324 HydrophobicContact CD2-CB 4.42Å; Y310-L325 HydrophobicContact CE2-CD2 3.94Å; Y310-Y328 HydrophobicContact CD2-CD2 4.19Å; Y310-Y328 HydrophobicContact CD2-CG 4.3Å; Y310-Y328 HydrophobicContact CG-CD2 4.27Å; Y310-A515 HydrophobicContact CD1-CB 3.64Å; Y310-A515 HydrophobicContact CE1-CB 3.73Å; Y310-R516 PolarHBondContact OH-O 2.93Å; Y310-P517 WeakPolarHBondContact OH-CA 3.28Å; Y310-S520 PolarHBondContact OH-OG 3.48Å
311	E	87.2	Confident	84.5	Confident	45 Å²	45	60.5 Å²	60.5	21%	0.21	39%	0.39	C	S	.	.	H	α-helix	trans	-59.1	-45.7	-178.3	-75.9	-61.4	131.8	0	0	112.2	F307 I308 S315 G514 A515	F307-E311 HydrophobicContact CD2-CG 4.19Å; F307-E311 HydrophobicContact CE1-CG 4.43Å; F307-E311 HydrophobicContact CE2-CG 3.63Å; F307-E311 HydrophobicContact CZ-CG 3.76Å; F307-E311 PolarHBondContact O-N 3.35Å; I308-E311 PolarHBondContact O-N 3.05Å; E311-S315 WeakPolarHBondContact O-CB 3.37Å; E311-S315 PolarHBondContact O-N 3.32Å; E311-S315 PolarHBondContact O-OG 3.47Å; E311-G514 VanDerWaalsContact OE1-C 3.3Å; E311-A515 WeakPolarHBondContact OE1-CA 3.4Å; E311-A515 PolarHBondContact OE1-N 3.49Å
312	V	87.1	Confident	84.1	Confident	99 Å²	99	62.8 Å²	62.8	60%	0.6	39%	0.39	S	S	*	.	H	α-helix	trans	-66.7	-41.9	-179.7	172.5	0	0	0	0	111.6	I308 Y310 G316	I308-V312 HydrophobicContact CG2-CG2 4.32Å; I308-V312 WeakPolarHBondContact O-CB 3.27Å; I308-V312 VanDerWaalsContact O-CG2 3.25Å; I308-V312 WeakPolarHBondContact O-CG2 3.39Å; I308-V312 PolarHBondContact O-N 3.47Å; Y310-V312 PolarHBondContact O-N 2.74Å; V312-G316 WeakPolarHBondContact O-CA 3.47Å; V312-G316 PolarHBondContact O-N 3.5Å
313	Q	86	Confident	83.7	Confident	45 Å²	45	64.5 Å²	64.5	21%	0.21	40%	0.396	C	S	.	.	H	α-helix	trans	-78.2	-32.7	-176.8	-71.7	-162.6	25.5	0	0	113.6	I309 Y310 R320 A324	I309-Q313 HydrophobicContact CG2-CG 4.34Å; I309-Q313 VanDerWaalsContact O-CB 3.29Å; I309-Q313 WeakPolarHBondContact O-CB 3.44Å; I309-Q313 VanDerWaalsContact O-CG 3.32Å; I309-Q313 WeakPolarHBondContact O-CG 3.4Å; I309-Q313 PolarHBondContact O-N 3.45Å; Y310-Q313 PolarHBondContact O-N 2.92Å; Q313-R320 PolarHBondContact OE1-O 2.94Å; Q313-A324 HydrophobicContact CB-CB 3.82Å
314	V	80.5	Confident	83.5	Confident	43 Å²	43	64.6 Å²	64.6	26%	0.261	40%	0.396	S	S	.	.	H	α-helix	trans	-76.2	-40.7	176.4	176.2	0	0	0	0	110.6	Y310 T321 A324	Y310-V314 HydrophobicContact CD1-CG2 4.42Å; Y310-V314 HydrophobicContact CD2-CG2 3.88Å; Y310-V314 HydrophobicContact CE1-CG2 4.19Å; Y310-V314 HydrophobicContact CE2-CG2 3.63Å; Y310-V314 HydrophobicContact CG-CG2 4.27Å; Y310-V314 WeakPolarHBondContact O-CB 3.2Å; Y310-V314 VanDerWaalsContact O-CG2 3.27Å; Y310-V314 WeakPolarHBondContact O-CG2 3.49Å; Y310-V314 PolarHBondContact O-N 3.01Å; V314-T321 HydrophobicContact CG2-CG2 4.28Å; V314-A324 HydrophobicContact CG2-CB 4.25Å
315	S	72.8	Confident	83.3	Confident	93 Å²	93	62.1 Å²	62.1	65%	0.65	38%	0.384	S	S	*	.	H	α-helix	trans	-76.8	-25.8	177.9	-60	0	0	0	0	113.5	E311 G317	E311-S315 WeakPolarHBondContact O-CB 3.37Å; E311-S315 PolarHBondContact O-N 3.32Å; E311-S315 PolarHBondContact O-OG 3.47Å; S315-G317 VanDerWaalsContact C-N 3.29Å; S315-G317 PolarHBondContact O-N 3.25Å
316	G	68.1	Low	83.2	Confident	57 Å²	57	61.7 Å²	61.7	59%	0.588	38%	0.376	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.3	8.1	-170.4	0	0	0	0	0	117	V312 G318	V312-G316 WeakPolarHBondContact O-CA 3.47Å; V312-G316 PolarHBondContact O-N 3.5Å; G316-G318 PolarHBondContact O-N 3.41Å
317	G	62.1	Low	83.1	Confident	76 Å²	76	63.8 Å²	63.8	78%	0.784	39%	0.386	S	S	*	.			trans	63	0.6	172.6	0	0	0	0	0	117.1	S315 G319	S315-G317 VanDerWaalsContact C-N 3.29Å; S315-G317 PolarHBondContact O-N 3.25Å; G317-G319 VanDerWaalsContact C-N 3.35Å; G317-G319 PolarHBondContact O-N 3.29Å
318	G	60.2	Low	83.1	Confident	56 Å²	56	63 Å²	63	58%	0.577	38%	0.382	S	S	*	.	S	Bend	trans	-85.7	18.4	-167.2	0	0	0	0	0	116.8	G316 R320	G316-G318 PolarHBondContact O-N 3.41Å; G318-R320 PolarHBondContact O-N 2.86Å
319	G	66.6	Low	83.2	Confident	73 Å²	73	58.1 Å²	58.1	75%	0.753	36%	0.357	S	S	*	.	S	Bend	trans	64.6	10.7	179	0	0	0	0	0	115.7	G317	G317-G319 VanDerWaalsContact C-N 3.35Å; G317-G319 PolarHBondContact O-N 3.29Å
320	R	82.1	Confident	83.5	Confident	158 Å²	158	57.2 Å²	57.2	60%	0.596	36%	0.357	S	S	*	.			trans	-92.1	10.9	-179.5	-64.1	-178.4	-175.7	149.3	1	114	Q313 G318 R322 Q323 A324	Q313-R320 PolarHBondContact OE1-O 2.94Å; G318-R320 PolarHBondContact O-N 2.86Å; R320-R322 VanDerWaalsContact C-N 3.28Å; R320-R322 PolarHBondContact O-N 2.92Å; R320-Q323 WeakPolarHBondContact O-CB 3.01Å; R320-Q323 PolarHBondContact O-N 3.46Å; R320-A324 PolarHBondContact O-N 2.87Å
321	T	84	Confident	83.7	Confident	47 Å²	47	57.9 Å²	57.9	29%	0.288	36%	0.36	S	S	.	.	H	α-helix	trans	-53.2	-42.2	-179.5	-49	0	0	0	0	112.6	V314 Q323 A324 L325	V314-T321 HydrophobicContact CG2-CG2 4.28Å; T321-Q323 VanDerWaalsContact C-N 3.34Å; T321-Q323 PolarHBondContact O-N 3.25Å; T321-A324 PolarHBondContact O-N 3.06Å; T321-L325 HydrophobicContact CG2-CD1 4.05Å; T321-L325 HydrophobicContact CG2-CG 4.47Å; T321-L325 WeakPolarHBondContact O-CB 3.23Å; T321-L325 WeakPolarHBondContact O-CG 3.36Å; T321-L325 PolarHBondContact O-N 3.22Å
322	R	86.7	Confident	84.1	Confident	133 Å²	133	56 Å²	56	50%	0.502	35%	0.351	S	S	.	.	H	α-helix	trans	-61	-41.5	177.7	-172.2	174.2	179.7	125.6	-3.4	112	R320 V326 D397	R320-R322 VanDerWaalsContact C-N 3.28Å; R320-R322 PolarHBondContact O-N 2.92Å; R322-V326 VanDerWaalsContact O-CG2 3.31Å; R322-V326 WeakPolarHBondContact O-CG2 3.2Å; R322-V326 PolarHBondContact O-N 3.16Å; R322-V326 VanDerWaalsContact O-N 3.07Å; R322-D397 IonicContact CZ-OD1 3.16Å; R322-D397 IonicContact NH1-OD1 3.67Å; R322-D397 PolarHBondContact NH1-OD1 3.02Å; R322-D397 IonicContact NH2-OD1 2.82Å; R322-D397 PolarHBondContact NH2-OD1 3.02Å
323	Q	88.5	Confident	84.5	Confident	110 Å²	110	52.8 Å²	52.8	51%	0.514	33%	0.33	S	S	.	.	H	α-helix	trans	-67.6	-43.7	178.3	-173.5	178.9	5.2	0	0	111.2	R320 T321 L325 V326 I327	R320-Q323 WeakPolarHBondContact O-CB 3.01Å; R320-Q323 PolarHBondContact O-N 3.46Å; T321-Q323 VanDerWaalsContact C-N 3.34Å; T321-Q323 PolarHBondContact O-N 3.25Å; Q323-L325 PolarHBondContact O-N 2.96Å; Q323-V326 PolarHBondContact O-N 3.29Å; Q323-I327 HydrophobicContact CG-CD1 4.19Å; Q323-I327 WeakPolarHBondContact O-CG1 3.24Å; Q323-I327 PolarHBondContact O-N 3.25Å; Q323-I327 VanDerWaalsContact O-N 3.08Å
324	A	90.9	Very high	85	Confident	1 Å²	1	54.5 Å²	54.5	1%	0.008	34%	0.344	C	S	.	.	H	α-helix	trans	-59.8	-44.2	176.4	0	0	0	0	0	112.1	Y310 Q313 V314 R320 T321 I327 Y328	Y310-A324 HydrophobicContact CD2-CB 4.42Å; Q313-A324 HydrophobicContact CB-CB 3.82Å; V314-A324 HydrophobicContact CG2-CB 4.25Å; R320-A324 PolarHBondContact O-N 2.87Å; T321-A324 PolarHBondContact O-N 3.06Å; A324-I327 PolarHBondContact O-N 3.41Å; A324-Y328 WeakPolarHBondContact O-CB 3.4Å; A324-Y328 PolarHBondContact O-N 3.42Å
325	L	90.7	Very high	85.8	Confident	4 Å²	4	52.4 Å²	52.4	2%	0.021	33%	0.331	C	S	.	.	H	α-helix	trans	-62.6	-44.7	176.6	-73.5	168.7	0	0	0	112.1	Y310 T321 Q323 I327 Y328 Y329 L399 P517	Y310-L325 HydrophobicContact CE2-CD2 3.94Å; T321-L325 HydrophobicContact CG2-CD1 4.05Å; T321-L325 HydrophobicContact CG2-CG 4.47Å; T321-L325 WeakPolarHBondContact O-CB 3.23Å; T321-L325 WeakPolarHBondContact O-CG 3.36Å; T321-L325 PolarHBondContact O-N 3.22Å; Q323-L325 PolarHBondContact O-N 2.96Å; L325-I327 VanDerWaalsContact C-N 3.33Å; L325-I327 PolarHBondContact O-N 3.4Å; L325-Y328 PolarHBondContact O-N 2.95Å; L325-Y329 HydrophobicContact CB-CD2 4.36Å; L325-Y329 HydrophobicContact CD2-CE2 4.13Å; L325-Y329 WeakPolarHBondContact O-CB 3.43Å; L325-Y329 VanDerWaalsContact O-CD2 3.25Å; L325-Y329 WeakPolarHBondContact O-CD2 3.18Å; L325-Y329 PolarHBondContact O-N 3.27Å; L325-L399 HydrophobicContact CB-CD1 3.94Å; L325-L399 HydrophobicContact CD1-CD2 4.1Å; L325-P517 HydrophobicContact CD2-CB 3.76Å
326	V	92.6	Very high	86.9	Confident	39 Å²	39	48 Å²	48	24%	0.236	30%	0.3	C	S	.	.	H	α-helix	trans	-59.6	-44.5	177.2	169.7	0	0	0	0	110.9	R322 Q323 S330 L398 L402	R322-V326 VanDerWaalsContact O-CG2 3.31Å; R322-V326 WeakPolarHBondContact O-CG2 3.2Å; R322-V326 PolarHBondContact O-N 3.16Å; R322-V326 VanDerWaalsContact O-N 3.07Å; Q323-V326 PolarHBondContact O-N 3.29Å; V326-S330 WeakPolarHBondContact O-CB 3.41Å; V326-S330 PolarHBondContact O-N 2.86Å; V326-S330 PolarHBondContact O-OG 3.47Å; V326-L398 HydrophobicContact CG2-CD2 4.47Å; V326-L402 HydrophobicContact CB-CD1 4.33Å; V326-L402 HydrophobicContact CG1-CD1 4.11Å; V326-L402 HydrophobicContact CG2-CD1 4.08Å
327	I	93.1	Very high	88.3	Confident	56 Å²	56	46.1 Å²	46.1	29%	0.287	28%	0.281	S	S	.	.	H	α-helix	trans	-63.4	-45.6	177.7	-65.4	167.3	0	0	0	110.4	V306 Q323 A324 L325 S330 F331	V306-I327 HydrophobicContact CG1-CG2 4.1Å; V306-I327 HydrophobicContact CG2-CG2 4Å; Q323-I327 HydrophobicContact CG-CD1 4.19Å; Q323-I327 WeakPolarHBondContact O-CG1 3.24Å; Q323-I327 PolarHBondContact O-N 3.25Å; Q323-I327 VanDerWaalsContact O-N 3.08Å; A324-I327 PolarHBondContact O-N 3.41Å; L325-I327 VanDerWaalsContact C-N 3.33Å; L325-I327 PolarHBondContact O-N 3.4Å; I327-S330 PolarHBondContact O-N 2.95Å; I327-F331 WeakPolarHBondContact O-CB 3.07Å; I327-F331 PolarHBondContact O-N 3.43Å
328	Y	93.6	Very high	89.9	Confident	14 Å²	14	45.3 Å²	45.3	6%	0.055	26%	0.258	C	S	.	.	H	α-helix	trans	-60.3	-53.4	-180	-179.5	-83.6	0	0	0	112.2	V306 Y310 A324 L325 S330 F331 N332 M510 A515 P517	V306-Y328 HydrophobicContact CG1-CD2 4.44Å; Y310-Y328 HydrophobicContact CD2-CD2 4.19Å; Y310-Y328 HydrophobicContact CD2-CG 4.3Å; Y310-Y328 HydrophobicContact CG-CD2 4.27Å; A324-Y328 WeakPolarHBondContact O-CB 3.4Å; A324-Y328 PolarHBondContact O-N 3.42Å; L325-Y328 PolarHBondContact O-N 2.95Å; Y328-S330 PolarHBondContact O-N 3Å; Y328-F331 PolarHBondContact O-N 3.17Å; Y328-N332 WeakPolarHBondContact CE1-ND2 3.36Å; Y328-N332 VanDerWaalsContact CZ-ND2 3.28Å; Y328-N332 PolarHBondContact O-N 2.96Å; Y328-N332 PolarHBondContact O-ND2 3.47Å; Y328-M510 HydrophobicContact CE2-CB 4.45Å; Y328-M510 HydrophobicContact CE2-CG 4.49Å; Y328-M510 HydrophobicContact CE2-SD 3.87Å; Y328-A515 HydrophobicContact CE2-CB 4.23Å; Y328-P517 HydrophobicContact CD1-CB 4.15Å; Y328-P517 HydrophobicContact CD1-CG 4.04Å; Y328-P517 HydrophobicContact CE1-CB 4.14Å; Y328-P517 HydrophobicContact CE1-CG 3.52Å
329	Y	94.3	Very high	91.6	Very high	0 Å²	0	42.6 Å²	42.6	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-64	-41.4	179.8	-81.7	-69.3	0	0	0	111.4	L325 F331 N332 I333 L399 L402 D403 H406 P517 N521	L325-Y329 HydrophobicContact CB-CD2 4.36Å; L325-Y329 HydrophobicContact CD2-CE2 4.13Å; L325-Y329 WeakPolarHBondContact O-CB 3.43Å; L325-Y329 VanDerWaalsContact O-CD2 3.25Å; L325-Y329 WeakPolarHBondContact O-CD2 3.18Å; L325-Y329 PolarHBondContact O-N 3.27Å; Y329-F331 PolarHBondContact O-N 2.73Å; Y329-N332 PolarHBondContact O-N 3.21Å; Y329-I333 WeakPolarHBondContact O-CB 3.48Å; Y329-I333 WeakPolarHBondContact O-CD1 2.99Å; Y329-I333 VanDerWaalsContact O-CG1 3.24Å; Y329-I333 WeakPolarHBondContact O-CG1 3.26Å; Y329-I333 PolarHBondContact O-N 3.03Å; Y329-L399 HydrophobicContact CD2-CD1 3.81Å; Y329-L399 HydrophobicContact CE2-CD1 3.94Å; Y329-L402 HydrophobicContact CG-CB 4.47Å; Y329-D403 HydrophobicContact CE1-CB 4.35Å; Y329-D403 WeakPolarHBondContact CE1-OD1 3.11Å; Y329-D403 PolarHBondContact OH-OD1 3.41Å; Y329-H406 HydrophobicContact CD1-CB 3.8Å; Y329-H406 AromaticContact CD1-CG 3.82Å; Y329-H406 HydrophobicContact CE1-CB 4.12Å; Y329-H406 AromaticContact CE1-CG 3.96Å; Y329-H406 AromaticContact CE1-ND1 3.91Å; Y329-P517 HydrophobicContact CE2-CB 4.25Å; Y329-N521 PolarHBondContact OH-ND2 3.42Å
330	S	95.1	Very high	93	Very high	47 Å²	47	39.8 Å²	39.8	33%	0.329	20%	0.199	S	C	.	.	H	α-helix	trans	-60.6	-45.9	178.6	-58.2	0	0	0	0	111.8	V326 I327 Y328 V334	V326-S330 WeakPolarHBondContact O-CB 3.41Å; V326-S330 PolarHBondContact O-N 2.86Å; V326-S330 PolarHBondContact O-OG 3.47Å; I327-S330 PolarHBondContact O-N 2.95Å; Y328-S330 PolarHBondContact O-N 3Å; S330-V334 WeakPolarHBondContact O-CG2 3.27Å; S330-V334 PolarHBondContact O-N 3.32Å
331	F	96	Very high	93.7	Very high	19 Å²	19	37.3 Å²	37.3	8%	0.083	20%	0.197	C	C	.	.	H	α-helix	trans	-61.4	-47	175.3	170.7	-96.5	0	0	0	111.7	L299 I302 V306 I327 Y328 Y329 I333 V334 C335 M510	L299-F331 HydrophobicContact CD2-CE2 4.37Å; L299-F331 WeakPolarHBondContact O-CZ 3.21Å; I302-F331 HydrophobicContact CB-CE2 4.14Å; I302-F331 HydrophobicContact CG2-CD2 3.76Å; I302-F331 HydrophobicContact CG2-CE2 3.74Å; V306-F331 HydrophobicContact CB-CG 4.47Å; V306-F331 HydrophobicContact CG1-CB 4.21Å; V306-F331 HydrophobicContact CG1-CD1 4.49Å; V306-F331 HydrophobicContact CG1-CG 4.43Å; V306-F331 HydrophobicContact CG2-CB 4.11Å; V306-F331 HydrophobicContact CG2-CD2 4.3Å; V306-F331 HydrophobicContact CG2-CG 4.13Å; I327-F331 WeakPolarHBondContact O-CB 3.07Å; I327-F331 PolarHBondContact O-N 3.43Å; Y328-F331 PolarHBondContact O-N 3.17Å; Y329-F331 PolarHBondContact O-N 2.73Å; F331-I333 PolarHBondContact O-N 3.39Å; F331-V334 PolarHBondContact O-N 2.83Å; F331-C335 HydrophobicContact CE1-CB 4.42Å; F331-C335 HydrophobicContact CZ-CB 4.42Å; F331-C335 WeakPolarHBondContact O-CB 3.5Å; F331-C335 PolarHBondContact O-N 3.3Å; F331-M510 HydrophobicContact CD1-CE 3.78Å; F331-M510 HydrophobicContact CE1-CE 3.46Å; F331-M510 VanDerWaalsContact CE1-CE 3.46Å; F331-M510 HydrophobicContact CE1-SD 4.32Å; F331-M510 HydrophobicContact CZ-CE 4.39Å
332	N	94.8	Very high	94.2	Very high	7 Å²	7	36.8 Å²	36.8	4%	0.037	19%	0.193	C	C	.	.	H	α-helix	trans	-62.8	-42.7	-179.5	-83.8	-85.9	0	0	0	111.6	Y328 Y329 V334 C335 L336 L507	Y328-N332 WeakPolarHBondContact CE1-ND2 3.36Å; Y328-N332 VanDerWaalsContact CZ-ND2 3.28Å; Y328-N332 PolarHBondContact O-N 2.96Å; Y328-N332 PolarHBondContact O-ND2 3.47Å; Y329-N332 PolarHBondContact O-N 3.21Å; N332-V334 PolarHBondContact O-N 3.4Å; N332-C335 PolarHBondContact O-N 2.78Å; N332-L336 VanDerWaalsContact O-CB 3.27Å; N332-L336 WeakPolarHBondContact O-CB 3.28Å; N332-L336 WeakPolarHBondContact O-CG 3.34Å; N332-L336 PolarHBondContact O-N 3.05Å; N332-L507 WeakPolarHBondContact OD1-CD2 3.29Å
333	I	96.5	Very high	94.6	Very high	30 Å²	30	30.4 Å²	30.4	15%	0.154	17%	0.169	C	C	.	.	H	α-helix	trans	-56.6	-47.7	175	-74.7	165.2	0	0	0	111.2	Y329 F331 G337 L402 T405 H406 L409	Y329-I333 WeakPolarHBondContact O-CB 3.48Å; Y329-I333 WeakPolarHBondContact O-CD1 2.99Å; Y329-I333 VanDerWaalsContact O-CG1 3.24Å; Y329-I333 WeakPolarHBondContact O-CG1 3.26Å; Y329-I333 PolarHBondContact O-N 3.03Å; F331-I333 PolarHBondContact O-N 3.39Å; I333-G337 PolarHBondContact O-N 2.85Å; I333-L402 HydrophobicContact CD1-CB 4.4Å; I333-L402 HydrophobicContact CD1-CD2 3.75Å; I333-T405 HydrophobicContact CD1-CG2 3.97Å; I333-T405 HydrophobicContact CG1-CG2 4.16Å; I333-T405 HydrophobicContact CG2-CG2 4.09Å; I333-H406 HydrophobicContact CG1-CB 4.12Å; I333-L409 HydrophobicContact CB-CD1 4.16Å; I333-L409 HydrophobicContact CG1-CD1 4.32Å; I333-L409 HydrophobicContact CG2-CD1 3.66Å
334	V	96.7	Very high	94.8	Very high	81 Å²	81	28.1 Å²	28.1	49%	0.491	16%	0.16	S	C	.	.	H	α-helix	trans	-62.6	-46.9	177.8	173	0	0	0	0	110.9	S330 F331 N332 G337 L338	S330-V334 WeakPolarHBondContact O-CG2 3.27Å; S330-V334 PolarHBondContact O-N 3.32Å; F331-V334 PolarHBondContact O-N 2.83Å; N332-V334 PolarHBondContact O-N 3.4Å; V334-G337 PolarHBondContact O-N 3.14Å; V334-L338 HydrophobicContact CG1-CD1 4Å; V334-L338 WeakPolarHBondContact O-CB 3.36Å; V334-L338 WeakPolarHBondContact O-CG 3.38Å; V334-L338 PolarHBondContact O-N 3.13Å
335	C	96.1	Very high	94.8	Very high	0 Å²	0	31 Å²	31	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-63.3	-45.2	-180	-171.6	0	0	0	0	112.1	F331 N332 L338 T339	F331-C335 HydrophobicContact CE1-CB 4.42Å; F331-C335 HydrophobicContact CZ-CB 4.42Å; F331-C335 WeakPolarHBondContact O-CB 3.5Å; F331-C335 PolarHBondContact O-N 3.3Å; N332-C335 PolarHBondContact O-N 2.78Å; C335-L338 PolarHBondContact O-N 2.92Å; C335-T339 WeakPolarHBondContact O-CB 3.44Å; C335-T339 VanDerWaalsContact O-CG2 3.3Å; C335-T339 WeakPolarHBondContact O-CG2 3.47Å; C335-T339 PolarHBondContact O-N 2.98Å; C335-T339 PolarHBondContact O-OG1 3.3Å
336	L	96.4	Very high	94.7	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-66.6	-40.4	178.1	-67.2	170.5	0	0	0	111.6	N332 T339 T340 L409 M410 Q413 L507	N332-L336 VanDerWaalsContact O-CB 3.27Å; N332-L336 WeakPolarHBondContact O-CB 3.28Å; N332-L336 WeakPolarHBondContact O-CG 3.34Å; N332-L336 PolarHBondContact O-N 3.05Å; L336-T339 WeakPolarHBondContact CA-OG1 3.5Å; L336-T339 PolarHBondContact O-OG1 3.03Å; L336-T340 VanDerWaalsContact O-CB 3.3Å; L336-T340 WeakPolarHBondContact O-CB 3.25Å; L336-T340 PolarHBondContact O-N 3.11Å; L336-T340 PolarHBondContact O-OG1 3.39Å; L336-L409 HydrophobicContact CB-CB 4.08Å; L336-L409 HydrophobicContact CD1-CB 4.39Å; L336-M410 HydrophobicContact CD1-CG 3.63Å; L336-M410 HydrophobicContact CD1-SD 3.51Å; L336-M410 VanDerWaalsContact CD1-SD 3.51Å; L336-M410 HydrophobicContact CD2-SD 3.61Å; L336-M410 HydrophobicContact CG-SD 4.21Å; L336-Q413 HydrophobicContact CB-CB 4.48Å; L336-Q413 HydrophobicContact CB-CG 4.41Å; L336-Q413 HydrophobicContact CD2-CB 4.12Å; L336-Q413 HydrophobicContact CD2-CG 3.72Å; L336-L507 HydrophobicContact CD2-CD1 4.01Å
337	G	97.3	Very high	94.6	Very high	18 Å²	18	29.3 Å²	29.3	19%	0.186	17%	0.171	C	C	.	.	H	α-helix	trans	-60.1	-49.8	174.2	0	0	0	0	0	112.1	I333 V334 T340 L341	I333-G337 PolarHBondContact O-N 2.85Å; V334-G337 PolarHBondContact O-N 3.14Å; G337-T340 WeakPolarHBondContact O-CB 3.39Å; G337-T340 PolarHBondContact O-N 3.28Å; G337-L341 WeakPolarHBondContact O-CG 3.42Å; G337-L341 PolarHBondContact O-N 3.15Å
338	L	96.2	Very high	94.3	Very high	58 Å²	58	30.3 Å²	30.3	30%	0.304	18%	0.176	S	C	.	.	H	α-helix	trans	-62.8	-46.3	178.6	-71.4	173	0	0	0	112.3	L299 V334 C335 T340 L341 V342 F499	L299-L338 HydrophobicContact CD1-CD1 3.96Å; V334-L338 HydrophobicContact CG1-CD1 4Å; V334-L338 WeakPolarHBondContact O-CB 3.36Å; V334-L338 WeakPolarHBondContact O-CG 3.38Å; V334-L338 PolarHBondContact O-N 3.13Å; C335-L338 PolarHBondContact O-N 2.92Å; L338-T340 VanDerWaalsContact C-N 3.29Å; L338-T340 PolarHBondContact O-N 3.26Å; L338-L341 PolarHBondContact O-N 2.88Å; L338-V342 WeakPolarHBondContact O-CB 3.45Å; L338-V342 WeakPolarHBondContact O-CG2 3.45Å; L338-V342 PolarHBondContact O-N 3.02Å; L338-F499 HydrophobicContact CB-CZ 4.12Å
339	T	95.6	Very high	93.9	Very high	0 Å²	0	31.1 Å²	31.1	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-64	-34.2	177.6	51.6	0	0	0	0	112.4	C335 L336 S343 Q413 F499 L500 C503	C335-T339 WeakPolarHBondContact O-CB 3.44Å; C335-T339 VanDerWaalsContact O-CG2 3.3Å; C335-T339 WeakPolarHBondContact O-CG2 3.47Å; C335-T339 PolarHBondContact O-N 2.98Å; C335-T339 PolarHBondContact O-OG1 3.3Å; L336-T339 WeakPolarHBondContact CA-OG1 3.5Å; L336-T339 PolarHBondContact O-OG1 3.03Å; T339-S343 VanDerWaalsContact O-CB 3.29Å; T339-S343 WeakPolarHBondContact O-CB 3.31Å; T339-S343 PolarHBondContact O-N 2.93Å; T339-S343 PolarHBondContact O-OG 2.94Å; T339-Q413 VanDerWaalsContact OG1-CG 3.28Å; T339-Q413 WeakPolarHBondContact OG1-CG 3.34Å; T339-F499 HydrophobicContact CG2-CE1 4.07Å; T339-F499 HydrophobicContact CG2-CZ 4.45Å; T339-L500 HydrophobicContact CG2-CD2 4.05Å; T339-C503 HydrophobicContact CG2-CB 3.48Å; T339-C503 VanDerWaalsContact CG2-CB 3.48Å
340	T	96.8	Very high	93	Very high	13 Å²	13	31.3 Å²	31.3	8%	0.08	18%	0.181	C	C	.	.	H	α-helix	trans	-63.2	-51.7	172.6	-59.2	0	0	0	0	111.5	L336 G337 L338 V342 S343 L344 A412 Q413 F416	L336-T340 VanDerWaalsContact O-CB 3.3Å; L336-T340 WeakPolarHBondContact O-CB 3.25Å; L336-T340 PolarHBondContact O-N 3.11Å; L336-T340 PolarHBondContact O-OG1 3.39Å; G337-T340 WeakPolarHBondContact O-CB 3.39Å; G337-T340 PolarHBondContact O-N 3.28Å; L338-T340 VanDerWaalsContact C-N 3.29Å; L338-T340 PolarHBondContact O-N 3.26Å; T340-V342 VanDerWaalsContact C-N 3.31Å; T340-V342 PolarHBondContact O-N 2.99Å; T340-S343 PolarHBondContact O-N 3.39Å; T340-L344 WeakPolarHBondContact O-CB 3.37Å; T340-L344 PolarHBondContact O-N 3.27Å; T340-A412 HydrophobicContact CG2-CB 4.3Å; T340-Q413 WeakPolarHBondContact OG1-CA 3.06Å; T340-Q413 VanDerWaalsContact OG1-CB 3.26Å; T340-Q413 WeakPolarHBondContact OG1-CB 3.25Å; T340-F416 HydrophobicContact CG2-CB 4.49Å; T340-F416 HydrophobicContact CG2-CD2 3.55Å; T340-F416 HydrophobicContact CG2-CE2 4.18Å; T340-F416 HydrophobicContact CG2-CG 4.35Å
341	L	95.9	Very high	92.2	Very high	107 Å²	107	38.1 Å²	38.1	56%	0.56	20%	0.2	S	C	*	.	H	α-helix	trans	-60.3	-41.1	179.9	-70.6	173.4	0	0	0	112.2	G337 L338 S345	G337-L341 WeakPolarHBondContact O-CG 3.42Å; G337-L341 PolarHBondContact O-N 3.15Å; L338-L341 PolarHBondContact O-N 2.88Å; L341-S345 WeakPolarHBondContact O-CB 3.37Å; L341-S345 PolarHBondContact O-N 3.32Å; L341-S345 PolarHBondContact O-OG 3.28Å
342	V	94.6	Very high	91.2	Very high	35 Å²	35	44.2 Å²	44.2	21%	0.212	23%	0.226	C	C	.	.	H	α-helix	trans	-69.5	-42.2	178.6	169.7	0	0	0	0	111.5	L338 T340 L344 S345 G346 I496 F499 L500	L338-V342 WeakPolarHBondContact O-CB 3.45Å; L338-V342 WeakPolarHBondContact O-CG2 3.45Å; L338-V342 PolarHBondContact O-N 3.02Å; T340-V342 VanDerWaalsContact C-N 3.31Å; T340-V342 PolarHBondContact O-N 2.99Å; V342-L344 VanDerWaalsContact C-N 3.33Å; V342-L344 PolarHBondContact O-N 3.2Å; V342-S345 PolarHBondContact O-N 2.88Å; V342-G346 PolarHBondContact O-N 3.45Å; V342-I496 HydrophobicContact CG1-CB 4.17Å; V342-I496 HydrophobicContact CG1-CG1 4Å; V342-I496 HydrophobicContact CG1-CG2 3.66Å; V342-F499 HydrophobicContact CB-CD1 4.05Å; V342-F499 HydrophobicContact CB-CE1 3.94Å; V342-F499 HydrophobicContact CG1-CD1 3.73Å; V342-F499 HydrophobicContact CG1-CE1 4.16Å; V342-F499 HydrophobicContact CG2-CD1 3.95Å; V342-F499 HydrophobicContact CG2-CE1 3.69Å; V342-F499 HydrophobicContact CG2-CZ 4.46Å; V342-L500 HydrophobicContact CB-CD2 4.3Å; V342-L500 HydrophobicContact CG1-CD1 4.37Å; V342-L500 HydrophobicContact CG1-CD2 4.03Å; V342-L500 HydrophobicContact CG1-CG 4.02Å
343	S	94.1	Very high	90	Very high	0 Å²	0	45.1 Å²	45.1	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-63.9	-39.8	176.1	-57.9	0	0	0	0	111.8	T339 T340 S347	T339-S343 VanDerWaalsContact O-CB 3.29Å; T339-S343 WeakPolarHBondContact O-CB 3.31Å; T339-S343 PolarHBondContact O-N 2.93Å; T339-S343 PolarHBondContact O-OG 2.94Å; T340-S343 PolarHBondContact O-N 3.39Å; S343-S347 WeakPolarHBondContact O-CB 3.43Å; S343-S347 PolarHBondContact O-N 3.18Å; S343-S347 PolarHBondContact O-OG 3.15Å
344	L	94	Very high	88.2	Confident	62 Å²	62	55.5 Å²	55.5	33%	0.325	27%	0.269	S	S	.	.	H	α-helix	trans	-64.7	-45.9	175.3	179.9	60.4	0	0	0	111.2	T340 V342 G346 S347 I348 F416	T340-L344 WeakPolarHBondContact O-CB 3.37Å; T340-L344 PolarHBondContact O-N 3.27Å; V342-L344 VanDerWaalsContact C-N 3.33Å; V342-L344 PolarHBondContact O-N 3.2Å; L344-G346 PolarHBondContact O-N 3.27Å; L344-S347 PolarHBondContact O-N 3.38Å; L344-I348 HydrophobicContact CD1-CD1 4.2Å; L344-I348 HydrophobicContact CD1-CG1 4.44Å; L344-I348 HydrophobicContact CG-CD1 4.01Å; L344-I348 VanDerWaalsContact O-CG1 3.28Å; L344-I348 WeakPolarHBondContact O-CG1 3.31Å; L344-I348 PolarHBondContact O-N 3.41Å; L344-F416 HydrophobicContact CD1-CD1 3.93Å; L344-F416 HydrophobicContact CD1-CE1 3.82Å
345	S	90.8	Very high	86.6	Confident	61 Å²	61	54.4 Å²	54.4	43%	0.427	26%	0.256	S	S	.	.	H	α-helix	trans	-61.8	-43.7	177.4	-64.4	0	0	0	0	111.6	L341 V342 S347 I348 I349	L341-S345 WeakPolarHBondContact O-CB 3.37Å; L341-S345 PolarHBondContact O-N 3.32Å; L341-S345 PolarHBondContact O-OG 3.28Å; V342-S345 PolarHBondContact O-N 2.88Å; S345-S347 PolarHBondContact O-N 3.48Å; S345-I348 PolarHBondContact O-N 3.4Å; S345-I349 WeakPolarHBondContact O-CD1 3.36Å; S345-I349 VanDerWaalsContact O-CG1 3.24Å; S345-I349 WeakPolarHBondContact O-CG1 3.46Å; S345-I349 PolarHBondContact O-N 2.97Å
346	G	89.3	Confident	84.6	Confident	0 Å²	0	58.3 Å²	58.3	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-59.6	-44.1	173.5	0	0	0	0	0	112.6	V342 L344 I348 I349 Y350	V342-G346 PolarHBondContact O-N 3.45Å; L344-G346 PolarHBondContact O-N 3.27Å; G346-I348 PolarHBondContact O-N 2.94Å; G346-I349 PolarHBondContact O-N 3.24Å; G346-Y350 WeakPolarHBondContact O-CB 3.45Å; G346-Y350 VanDerWaalsContact O-CD2 3.24Å; G346-Y350 WeakPolarHBondContact O-CD2 3.38Å; G346-Y350 PolarHBondContact O-N 3.4Å
347	S	88.8	Confident	82.8	Confident	8 Å²	8	61.8 Å²	61.8	6%	0.056	31%	0.305	C	S	.	.	H	α-helix	trans	-64	-39.6	177.1	-56.7	0	0	0	0	112	S343 L344 S345 Y350 R351 F420	S343-S347 WeakPolarHBondContact O-CB 3.43Å; S343-S347 PolarHBondContact O-N 3.18Å; S343-S347 PolarHBondContact O-OG 3.15Å; L344-S347 PolarHBondContact O-N 3.38Å; S345-S347 PolarHBondContact O-N 3.48Å; S347-Y350 WeakPolarHBondContact O-CB 3.22Å; S347-Y350 PolarHBondContact O-N 3.48Å; S347-R351 WeakPolarHBondContact O-CG 3.39Å; S347-R351 PolarHBondContact O-N 2.91Å; S347-F420 WeakPolarHBondContact OG-CB 3.41Å
348	I	87.4	Confident	81.1	Confident	77 Å²	77	64 Å²	64	40%	0.395	31%	0.313	S	S	.	.	H	α-helix	trans	-65.3	-47.4	175.7	-68.3	166.7	0	0	0	110.6	L344 S345 G346 Y350 R351 F352	L344-I348 HydrophobicContact CD1-CD1 4.2Å; L344-I348 HydrophobicContact CD1-CG1 4.44Å; L344-I348 HydrophobicContact CG-CD1 4.01Å; L344-I348 VanDerWaalsContact O-CG1 3.28Å; L344-I348 WeakPolarHBondContact O-CG1 3.31Å; L344-I348 PolarHBondContact O-N 3.41Å; S345-I348 PolarHBondContact O-N 3.4Å; G346-I348 PolarHBondContact O-N 2.94Å; I348-Y350 PolarHBondContact O-N 2.96Å; I348-R351 PolarHBondContact O-N 3.38Å; I348-R351 VanDerWaalsContact O-N 3.13Å; I348-F352 HydrophobicContact CG2-CD2 3.82Å; I348-F352 HydrophobicContact CG2-CE2 3.6Å; I348-F352 WeakPolarHBondContact O-CD2 3.39Å; I348-F352 PolarHBondContact O-N 2.75Å
349	I	84.6	Confident	79.3	Confident	30 Å²	30	69.4 Å²	69.4	15%	0.154	34%	0.336	C	S	.	.	H	α-helix	trans	-56	-42.7	176.3	-69.5	163.4	0	0	0	110.2	S345 G346 F352 D353 R489 L493 I496	S345-I349 WeakPolarHBondContact O-CD1 3.36Å; S345-I349 VanDerWaalsContact O-CG1 3.24Å; S345-I349 WeakPolarHBondContact O-CG1 3.46Å; S345-I349 PolarHBondContact O-N 2.97Å; G346-I349 PolarHBondContact O-N 3.24Å; I349-F352 PolarHBondContact O-N 3.04Å; I349-D353 PolarHBondContact O-N 2.91Å; I349-R489 HydrophobicContact CG2-CB 4.49Å; I349-R489 HydrophobicContact CG2-CG 4.37Å; I349-L493 HydrophobicContact CG2-CD2 4.25Å; I349-L493 HydrophobicContact CG2-CG 4.33Å; I349-I496 HydrophobicContact CD1-CD1 3.95Å
350	Y	76.6	Confident	77.7	Confident	4 Å²	4	76.9 Å²	76.9	2%	0.016	37%	0.371	C	S	.	.	H	α-helix	trans	-61.9	-47.6	176.1	-86.9	-42.9	0	0	0	112.3	G346 S347 I348 F352 D353 F420 S424 R427 L493	G346-Y350 WeakPolarHBondContact O-CB 3.45Å; G346-Y350 VanDerWaalsContact O-CD2 3.24Å; G346-Y350 WeakPolarHBondContact O-CD2 3.38Å; G346-Y350 PolarHBondContact O-N 3.4Å; S347-Y350 WeakPolarHBondContact O-CB 3.22Å; S347-Y350 PolarHBondContact O-N 3.48Å; I348-Y350 PolarHBondContact O-N 2.96Å; Y350-F352 PolarHBondContact O-N 3.33Å; Y350-F352 VanDerWaalsContact O-N 3.15Å; Y350-D353 WeakPolarHBondContact O-CA 3.41Å; Y350-D353 WeakPolarHBondContact O-CB 3.23Å; Y350-D353 PolarHBondContact O-N 2.93Å; Y350-F420 AromaticContact CD2-CD2 3.89Å; Y350-F420 HydrophobicContact CD2-CD2 3.89Å; Y350-F420 AromaticContact CD2-CE2 3.66Å; Y350-F420 HydrophobicContact CD2-CE2 3.66Å; Y350-F420 AromaticContact CE2-CD2 3.83Å; Y350-F420 HydrophobicContact CE2-CD2 3.83Å; Y350-F420 AromaticContact CE2-CE2 3.25Å; Y350-F420 HydrophobicContact CE2-CE2 3.25Å; Y350-F420 AromaticContact CE2-CZ 3.85Å; Y350-F420 HydrophobicContact CE2-CZ 3.85Å; Y350-S424 WeakPolarHBondContact CE2-OG 3.34Å; Y350-S424 PolarHBondContact OH-OG 3.24Å; Y350-R427 VanDerWaalsContact CB-NH2 3.31Å; Y350-R427 PolarHBondContact O-NH1 2.99Å; Y350-R427 PolarHBondContact O-NH2 2.99Å; Y350-L493 HydrophobicContact CD1-CD1 3.9Å; Y350-L493 HydrophobicContact CD1-CD2 4.19Å; Y350-L493 HydrophobicContact CD2-CD2 4.04Å; Y350-L493 HydrophobicContact CE1-CD1 3.29Å; Y350-L493 HydrophobicContact CE1-CD2 3.81Å; Y350-L493 HydrophobicContact CE1-CG 4.16Å; Y350-L493 HydrophobicContact CE2-CD2 3.57Å; Y350-L493 HydrophobicContact CG-CD2 4.32Å; Y350-L493 VanDerWaalsContact CZ-CD2 3.46Å
351	R	77.9	Confident	75.9	Confident	191 Å²	191	85.3 Å²	85.3	72%	0.721	41%	0.406	S	S	*	.	H	α-helix	trans	-58.4	-29.9	177.5	-75.4	-170	178.3	-168.1	1.4	113.8	S347 I348 D353	S347-R351 WeakPolarHBondContact O-CG 3.39Å; S347-R351 PolarHBondContact O-N 2.91Å; I348-R351 PolarHBondContact O-N 3.38Å; I348-R351 VanDerWaalsContact O-N 3.13Å; R351-D353 VanDerWaalsContact C-N 3.33Å
352	F	74.4	Confident	74.4	Confident	146 Å²	146	82.3 Å²	82.3	64%	0.64	39%	0.391	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.4	-7.2	175.5	-74.9	-67.7	0	0	0	114.4	I348 I349 Y350 R489	I348-F352 HydrophobicContact CG2-CD2 3.82Å; I348-F352 HydrophobicContact CG2-CE2 3.6Å; I348-F352 WeakPolarHBondContact O-CD2 3.39Å; I348-F352 PolarHBondContact O-N 2.75Å; I349-F352 PolarHBondContact O-N 3.04Å; Y350-F352 PolarHBondContact O-N 3.33Å; Y350-F352 VanDerWaalsContact O-N 3.15Å; F352-R489 PolarHBondContact O-NH1 3.4Å
353	D	69.8	Low	73	Confident	27 Å²	27	83.4 Å²	83.4	14%	0.144	40%	0.399	C	S	.	.	S	Bend	trans	-101	95.9	178.3	-170.2	34.5	0	0	0	109.8	I349 Y350 R351 R355 R427 R489	I349-D353 PolarHBondContact O-N 2.91Å; Y350-D353 WeakPolarHBondContact O-CA 3.41Å; Y350-D353 WeakPolarHBondContact O-CB 3.23Å; Y350-D353 PolarHBondContact O-N 2.93Å; R351-D353 VanDerWaalsContact C-N 3.33Å; D353-R355 PolarHBondContact O-N 3.29Å; D353-R355 IonicContact OD2-CZ 3.51Å; D353-R355 VanDerWaalsContact OD2-CZ 3.23Å; D353-R355 IonicContact OD2-NE 3.53Å; D353-R355 PolarHBondContact OD2-NE 2.89Å; D353-R355 IonicContact OD2-NH2 3.49Å; D353-R355 PolarHBondContact OD2-NH2 3.44Å; D353-R427 PolarHBondContact O-NH1 3.27Å; D353-R427 VanDerWaalsContact O-NH1 3.09Å; D353-R427 IonicContact OD2-NH1 2.68Å; D353-R489 IonicContact OD1-NH1 3.83Å
354	R	58.1	Low	71.6	Confident	248 Å²	248	83.8 Å²	83.8	94%	0.936	40%	0.401	S	S	*	.			trans	-71.3	59.3	-177.6	-69.4	176.1	100.5	172.9	6.4	112.2
355	R	63.2	Low	70.5	Confident	57 Å²	57	82.7 Å²	82.7	22%	0.215	39%	0.392	C	S	.	.	P	Polyproline II helix	trans	-78.2	144.7	164.9	-77.7	-172.4	-98	-176.2	-6.5	109.6	D353 M357	D353-R355 PolarHBondContact O-N 3.29Å; D353-R355 IonicContact OD2-CZ 3.51Å; D353-R355 VanDerWaalsContact OD2-CZ 3.23Å; D353-R355 IonicContact OD2-NE 3.53Å; D353-R355 PolarHBondContact OD2-NE 2.89Å; D353-R355 IonicContact OD2-NH2 3.49Å; D353-R355 PolarHBondContact OD2-NH2 3.44Å; R355-M357 PolarHBondContact O-N 3.37Å
356	A	53.8	Low	69.7	Low	82 Å²	82	83.7 Å²	83.7	68%	0.678	40%	0.396	S	S	*	.	P	Polyproline II helix	trans	-62.8	130.7	170.6	0	0	0	0	0	108.9	G428	A356-G428 PolarHBondContact O-N 3.34Å
357	M	60.2	Low	68.9	Low	73 Å²	73	84 Å²	84	36%	0.36	40%	0.398	S	S	.	.	B	Isolated β-bridge	trans	-73.2	135.2	173.5	-68.7	-64.1	-70.2	0	0	108.8	R355 H359 H426 R427	R355-M357 PolarHBondContact O-N 3.37Å; M357-H359 PolarHBondContact O-CD2 2.86Å; M357-H359 VanDerWaalsContact O-CD2 3.25Å; M357-H359 PolarHBondContact O-N 3.04Å; M357-H426 HydrophobicContact CE-CB 3.56Å; M357-R427 HydrophobicContact SD-CG 4.05Å
358	D	61.6	Low	68.4	Low	64 Å²	64	85.7 Å²	85.7	34%	0.342	41%	0.406	S	S	.	.			trans	-73	98.2	177.9	-87.2	-2.8	0	0	0	109.5	H360 R365 H426 G428	D358-H360 PolarHBondContact O-N 3.25Å; D358-R365 PolarHBondContact O-NH2 3.34Å; D358-H426 PolarHBondContact N-O 3.41Å; D358-G428 WeakPolarHBondContact OD1-CA 3.28Å; D358-G428 VanDerWaalsContact OD2-CA 3.3Å; D358-G428 WeakPolarHBondContact OD2-CA 3.3Å
359	H	58.6	Low	68.2	Low	173 Å²	173	83.7 Å²	83.7	80%	0.801	40%	0.397	S	S	*	.			trans	-74.5	-0.8	178.2	-71	-68.3	0	0	0	113.9	M357 K361	M357-H359 PolarHBondContact O-CD2 2.86Å; M357-H359 VanDerWaalsContact O-CD2 3.25Å; M357-H359 PolarHBondContact O-N 3.04Å; H359-K361 PolarHBondContact O-N 3.28Å
360	H	60.6	Low	68.1	Low	156 Å²	156	85 Å²	85	72%	0.722	41%	0.413	S	S	*	.			trans	-70.1	124	178	-156.2	72.5	0	0	0	110.8	D358 N362 R365	D358-H360 PolarHBondContact O-N 3.25Å; H360-N362 PolarHBondContact O-N 3.01Å; H360-R365 PolarHBondContact O-NH2 2.96Å
361	K	58.6	Low	68.4	Low	191 Å²	191	86.4 Å²	86.4	83%	0.83	42%	0.421	S	S	*	.			trans	-75.1	90	178.9	-71	-176.4	179.8	179.1	0	109.9	H359	H359-K361 PolarHBondContact O-N 3.28Å
362	N	65.6	Low	68.8	Low	44 Å²	44	77.4 Å²	77.4	24%	0.235	39%	0.387	C	S	.	.			trans	-87.3	114.4	169.2	-175.5	-5.1	0	0	0	110.1	H360 T364 R365 T366	H360-N362 PolarHBondContact O-N 3.01Å; N362-T364 PolarHBondContact O-N 3.34Å; N362-T364 PolarHBondContact OD1-N 3.17Å; N362-T364 VanDerWaalsContact OD1-N 3.11Å; N362-R365 HydrophobicContact CB-CB 4Å; N362-R365 PolarHBondContact O-N 3.4Å; N362-T366 PolarHBondContact O-N 3.49Å; N362-T366 PolarHBondContact O-OG1 3.11Å
363	P	64.3	Low	69.5	Low	58 Å²	58	74.5 Å²	74.5	38%	0.377	38%	0.376	S	S	.	.	H	α-helix	trans	-64.9	-24.3	-178.1	28.2	-37.1	0	0	0	113.9	L367	P363-L367 WeakPolarHBondContact O-CB 3.07Å; P363-L367 PolarHBondContact O-N 3.09Å; P363-L367 VanDerWaalsContact O-N 3.17Å
364	T	65.6	Low	70.3	Confident	8 Å²	8	74.6 Å²	74.6	5%	0.049	38%	0.384	C	S	.	.	H	α-helix	trans	-70	-47.5	174.2	-49.7	0	0	0	0	109.6	D95 H97 R267 N362 T366 L367 D368	D95-T364 PolarHBondContact OD2-OG1 3.42Å; H97-T364 HydrophobicContact CB-CG2 4.07Å; R267-T364 PolarHBondContact NH1-OG1 2.81Å; N362-T364 PolarHBondContact O-N 3.34Å; N362-T364 PolarHBondContact OD1-N 3.17Å; N362-T364 VanDerWaalsContact OD1-N 3.11Å; T364-T366 VanDerWaalsContact C-N 3.35Å; T364-T366 PolarHBondContact O-N 2.87Å; T364-L367 WeakPolarHBondContact O-CA 3.19Å; T364-L367 VanDerWaalsContact O-CB 3.3Å; T364-L367 WeakPolarHBondContact O-CB 3.38Å; T364-L367 PolarHBondContact O-N 3.49Å; T364-D368 VanDerWaalsContact O-CG 3.3Å; T364-D368 PolarHBondContact O-N 3.37Å
365	R	70.2	Confident	71.8	Confident	38 Å²	38	63 Å²	63	14%	0.143	34%	0.341	C	S	.	.	H	α-helix	trans	-60.3	-40.3	175.3	-167.6	178.1	72	-175.3	2.1	112.9	D358 H360 N362 L367 D368 V369 L425 H426	D358-R365 PolarHBondContact O-NH2 3.34Å; H360-R365 PolarHBondContact O-NH2 2.96Å; N362-R365 HydrophobicContact CB-CB 4Å; N362-R365 PolarHBondContact O-N 3.4Å; R365-L367 VanDerWaalsContact C-N 3.26Å; R365-L367 PolarHBondContact O-N 3.32Å; R365-D368 PolarHBondContact O-N 3.3Å; R365-V369 WeakPolarHBondContact O-CG2 3.34Å; R365-V369 PolarHBondContact O-N 3.36Å; R365-L425 WeakPolarHBondContact CD-O 3.4Å; R365-H426 PolarHBondContact NE-CD2 3.28Å; R365-H426 PolarHBondContact NE-NE2 3.33Å; R365-H426 PolarHBondContact NH2-CD2 3.13Å; R365-H426 VanDerWaalsContact NH2-CD2 3.26Å
366	T	73.9	Confident	73.2	Confident	83 Å²	83	60.2 Å²	60.2	51%	0.509	33%	0.33	S	S	.	.	H	α-helix	trans	-65.1	-32.2	174.9	-54.2	0	0	0	0	112.2	N362 T364 A370	N362-T366 PolarHBondContact O-N 3.49Å; N362-T366 PolarHBondContact O-OG1 3.11Å; T364-T366 VanDerWaalsContact C-N 3.35Å; T364-T366 PolarHBondContact O-N 2.87Å; T366-A370 PolarHBondContact O-N 2.78Å
367	L	73.9	Confident	75.1	Confident	7 Å²	7	61.3 Å²	61.3	4%	0.037	32%	0.324	C	S	.	.	H	α-helix	trans	-71	-44.5	175.8	175.9	57.5	0	0	0	111.4	Y259 V260 P363 T364 R365 V369 A370 L371	Y259-L367 HydrophobicContact CD1-CD1 3.66Å; Y259-L367 HydrophobicContact CD1-CD2 3.63Å; Y259-L367 HydrophobicContact CD1-CG 4.29Å; Y259-L367 HydrophobicContact CE1-CD1 3.31Å; Y259-L367 HydrophobicContact CE1-CD2 3.81Å; Y259-L367 HydrophobicContact CE1-CG 4.17Å; V260-L367 HydrophobicContact CB-CD2 4.33Å; V260-L367 HydrophobicContact CG2-CD2 3.46Å; V260-L367 VanDerWaalsContact CG2-CD2 3.46Å; P363-L367 WeakPolarHBondContact O-CB 3.07Å; P363-L367 PolarHBondContact O-N 3.09Å; P363-L367 VanDerWaalsContact O-N 3.17Å; T364-L367 WeakPolarHBondContact O-CA 3.19Å; T364-L367 VanDerWaalsContact O-CB 3.3Å; T364-L367 WeakPolarHBondContact O-CB 3.38Å; T364-L367 PolarHBondContact O-N 3.49Å; R365-L367 VanDerWaalsContact C-N 3.26Å; R365-L367 PolarHBondContact O-N 3.32Å; L367-V369 PolarHBondContact O-N 2.95Å; L367-A370 CarbonylContact O-C 3.54Å; L367-A370 WeakPolarHBondContact O-CA 3.43Å; L367-A370 PolarHBondContact O-N 3.45Å; L367-L371 HydrophobicContact CD1-CD1 4Å; L367-L371 HydrophobicContact CD1-CD2 4.39Å; L367-L371 HydrophobicContact CD1-CG 3.84Å; L367-L371 HydrophobicContact CD2-CD1 4.44Å; L367-L371 HydrophobicContact CG-CD1 3.77Å; L367-L371 HydrophobicContact CG-CG 4.15Å; L367-L371 WeakPolarHBondContact O-CG 3.34Å; L367-L371 PolarHBondContact O-N 2.92Å
368	D	77.3	Confident	76.5	Confident	42 Å²	42	58 Å²	58	23%	0.225	31%	0.309	C	S	.	.	H	α-helix	trans	-58.4	-38.2	178.9	-58.2	-28.1	0	0	0	111.2	T364 R365 L372	T364-D368 VanDerWaalsContact O-CG 3.3Å; T364-D368 PolarHBondContact O-N 3.37Å; R365-D368 PolarHBondContact O-N 3.3Å; D368-L372 VanDerWaalsContact O-CB 3.27Å; D368-L372 WeakPolarHBondContact O-CB 3.37Å; D368-L372 PolarHBondContact O-N 2.87Å
369	V	83.3	Confident	78.1	Confident	35 Å²	35	55.6 Å²	55.6	21%	0.212	30%	0.296	C	S	.	.	H	α-helix	trans	-64	-45.6	172.3	176.6	0	0	0	0	112.1	R365 L367 L371 L372 M373 I422	R365-V369 WeakPolarHBondContact O-CG2 3.34Å; R365-V369 PolarHBondContact O-N 3.36Å; L367-V369 PolarHBondContact O-N 2.95Å; V369-L371 VanDerWaalsContact C-N 3.34Å; V369-L372 PolarHBondContact O-N 3.39Å; V369-M373 WeakPolarHBondContact O-CB 3.18Å; V369-M373 PolarHBondContact O-N 3.14Å; V369-I422 HydrophobicContact CG1-CD1 3.87Å; V369-I422 HydrophobicContact CG1-CG1 4.18Å; V369-I422 HydrophobicContact CG2-CG1 4.17Å; V369-I422 HydrophobicContact CG2-CG2 4.12Å
370	A	82.5	Confident	79.8	Confident	58 Å²	58	48.9 Å²	48.9	48%	0.479	26%	0.263	S	S	.	.	H	α-helix	trans	-66	-37.5	-179.9	0	0	0	0	0	112	T366 L367 G374	T366-A370 PolarHBondContact O-N 2.78Å; L367-A370 CarbonylContact O-C 3.54Å; L367-A370 WeakPolarHBondContact O-CA 3.43Å; L367-A370 PolarHBondContact O-N 3.45Å; A370-G374 PolarHBondContact O-N 3.25Å
371	L	83.8	Confident	81.5	Confident	34 Å²	34	42.9 Å²	42.9	18%	0.178	24%	0.241	C	C	.	.	H	α-helix	trans	-66.9	-46.4	175	-71.8	168.5	0	0	0	111.1	T256 L367 V369 M373 G374 A375	T256-L371 HydrophobicContact CG2-CD1 3.45Å; T256-L371 VanDerWaalsContact CG2-CD1 3.45Å; T256-L371 HydrophobicContact CG2-CD2 3.81Å; T256-L371 HydrophobicContact CG2-CG 4.29Å; L367-L371 HydrophobicContact CD1-CD1 4Å; L367-L371 HydrophobicContact CD1-CD2 4.39Å; L367-L371 HydrophobicContact CD1-CG 3.84Å; L367-L371 HydrophobicContact CD2-CD1 4.44Å; L367-L371 HydrophobicContact CG-CD1 3.77Å; L367-L371 HydrophobicContact CG-CG 4.15Å; L367-L371 WeakPolarHBondContact O-CG 3.34Å; L367-L371 PolarHBondContact O-N 2.92Å; V369-L371 VanDerWaalsContact C-N 3.34Å; L371-M373 VanDerWaalsContact C-N 3.32Å; L371-M373 PolarHBondContact O-N 3.42Å; L371-G374 PolarHBondContact O-N 3.27Å; L371-A375 WeakPolarHBondContact O-CB 3.25Å; L371-A375 PolarHBondContact O-N 3.47Å
372	L	86.4	Confident	83.2	Confident	2 Å²	2	34 Å²	34	1%	0.01	20%	0.202	C	C	.	.	H	α-helix	trans	-59.7	-44	177.7	-170.8	73.2	0	0	0	111.4	D368 V369 A376 N418 I421 I422 Y547	D368-L372 VanDerWaalsContact O-CB 3.27Å; D368-L372 WeakPolarHBondContact O-CB 3.37Å; D368-L372 PolarHBondContact O-N 2.87Å; V369-L372 PolarHBondContact O-N 3.39Å; L372-A376 WeakPolarHBondContact O-CB 3.46Å; L372-A376 PolarHBondContact O-N 3.24Å; L372-A376 VanDerWaalsContact O-N 3.16Å; L372-N418 HydrophobicContact CD2-CB 4.36Å; L372-N418 WeakPolarHBondContact CD2-OD1 3.32Å; L372-N418 WeakPolarHBondContact CG-OD1 3.42Å; L372-I421 HydrophobicContact CD2-CB 4.13Å; L372-I421 HydrophobicContact CD2-CD1 4.48Å; L372-I421 HydrophobicContact CD2-CG2 3.86Å; L372-I422 HydrophobicContact CD2-CG1 4.13Å; L372-Y547 HydrophobicContact CD1-CD2 3.83Å; L372-Y547 HydrophobicContact CD1-CE2 3.43Å; L372-Y547 VanDerWaalsContact CD1-CE2 3.43Å; L372-Y547 HydrophobicContact CG-CD2 4.41Å; L372-Y547 HydrophobicContact CG-CE2 3.85Å; L372-Y547 WeakPolarHBondContact O-CD2 2.87Å
373	M	88.2	Confident	84.6	Confident	84 Å²	84	32.1 Å²	32.1	41%	0.414	19%	0.193	S	C	.	.	H	α-helix	trans	-68.6	-45.5	177	-168.9	63	66.7	0	0	111.9	V369 L371 A375 A376 L377	V369-M373 WeakPolarHBondContact O-CB 3.18Å; V369-M373 PolarHBondContact O-N 3.14Å; L371-M373 VanDerWaalsContact C-N 3.32Å; L371-M373 PolarHBondContact O-N 3.42Å; M373-A375 VanDerWaalsContact C-N 3.33Å; M373-A375 PolarHBondContact O-N 3.01Å; M373-A376 PolarHBondContact O-N 3.13Å; M373-L377 PolarHBondContact O-N 3.03Å
374	G	87.5	Confident	86.1	Confident	30 Å²	30	35.8 Å²	35.8	31%	0.309	20%	0.2	S	C	.	.	H	α-helix	trans	-62	-39.8	179.3	0	0	0	0	0	112.7	A370 L371 L377	A370-G374 PolarHBondContact O-N 3.25Å; L371-G374 PolarHBondContact O-N 3.27Å; G374-L377 WeakPolarHBondContact O-CB 3.47Å; G374-L377 PolarHBondContact O-N 3.43Å
375	A	89.8	Confident	87.5	Confident	3 Å²	3	40.1 Å²	40.1	3%	0.025	22%	0.216	C	C	.	.	H	α-helix	trans	-67.8	-37.1	176.4	0	0	0	0	0	112.4	L371 M373 L377 G378 F543 F546 Y547	L371-A375 WeakPolarHBondContact O-CB 3.25Å; L371-A375 PolarHBondContact O-N 3.47Å; M373-A375 VanDerWaalsContact C-N 3.33Å; M373-A375 PolarHBondContact O-N 3.01Å; A375-L377 PolarHBondContact O-N 3.44Å; A375-G378 PolarHBondContact O-N 2.83Å; A375-F543 CarbonylContact O-C 3.58Å; A375-F543 WeakPolarHBondContact O-CB 3.49Å; A375-F546 HydrophobicContact CB-CD1 3.73Å; A375-F546 HydrophobicContact CB-CE1 4.33Å; A375-Y547 HydrophobicContact CB-CD2 4.21Å
376	A	92.6	Very high	88.6	Confident	0 Å²	0	38.4 Å²	38.4	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-64.9	-26.7	176.2	0	0	0	0	0	113.2	L372 M373 G378 Q379 Y380 Y547	L372-A376 WeakPolarHBondContact O-CB 3.46Å; L372-A376 PolarHBondContact O-N 3.24Å; L372-A376 VanDerWaalsContact O-N 3.16Å; M373-A376 PolarHBondContact O-N 3.13Å; A376-G378 VanDerWaalsContact C-N 3.25Å; A376-G378 PolarHBondContact O-N 2.86Å; A376-Q379 PolarHBondContact O-N 3.06Å; A376-Q379 VanDerWaalsContact O-N 3.17Å; A376-Y380 HydrophobicContact CB-CE2 4.05Å; A376-Y380 PolarHBondContact O-N 2.99Å; A376-Y547 HydrophobicContact CB-CD2 3.99Å; A376-Y547 HydrophobicContact CB-CE2 4.01Å
377	L	92.1	Very high	89.6	Confident	105 Å²	105	35.9 Å²	35.9	55%	0.55	19%	0.193	S	C	.	.	H	α-helix	trans	-58.5	-34.7	179.3	-69.1	173.1	0	0	0	112.9	M373 G374 A375 Y380 A381	M373-L377 PolarHBondContact O-N 3.03Å; G374-L377 WeakPolarHBondContact O-CB 3.47Å; G374-L377 PolarHBondContact O-N 3.43Å; A375-L377 PolarHBondContact O-N 3.44Å; L377-Y380 HydrophobicContact CD2-CD2 4.33Å; L377-Y380 PolarHBondContact O-N 3.32Å; L377-A381 WeakPolarHBondContact O-CB 3.3Å; L377-A381 PolarHBondContact O-N 3.21Å
378	G	91.4	Very high	90.6	Very high	4 Å²	4	39 Å²	39	4%	0.041	21%	0.212	C	C	.	.	H	α-helix	trans	-62.3	-45.8	177	0	0	0	0	0	112	A375 A376 A381 I382 C540	A375-G378 PolarHBondContact O-N 2.83Å; A376-G378 VanDerWaalsContact C-N 3.25Å; A376-G378 PolarHBondContact O-N 2.86Å; G378-A381 PolarHBondContact O-N 3.47Å; G378-I382 PolarHBondContact O-N 2.83Å; G378-I382 VanDerWaalsContact O-N 3.11Å; G378-C540 WeakPolarHBondContact O-CB 3.33Å
379	Q	93.6	Very high	91.3	Very high	13 Å²	13	37.1 Å²	37.1	6%	0.061	20%	0.202	C	C	.	.	H	α-helix	trans	-69.9	-34.5	178.2	-68.2	-62	-45.4	0	0	112.5	A376 S383 M410 G544	A376-Q379 PolarHBondContact O-N 3.06Å; A376-Q379 VanDerWaalsContact O-N 3.17Å; Q379-S383 WeakPolarHBondContact O-CB 3.32Å; Q379-S383 PolarHBondContact O-N 2.99Å; Q379-S383 PolarHBondContact O-OG 3.33Å; Q379-M410 HydrophobicContact CB-CE 4.33Å; Q379-M410 HydrophobicContact CG-CE 4.29Å; Q379-G544 VanDerWaalsContact CG-CA 3.45Å
380	Y	95.4	Very high	91.7	Very high	32 Å²	32	35.8 Å²	35.8	13%	0.125	19%	0.194	C	C	.	.	H	α-helix	trans	-62.3	-45.2	170.6	-64.7	-25.3	0	0	0	111.8	A376 L377 S383 Y384 I411 H414 T415	A376-Y380 HydrophobicContact CB-CE2 4.05Å; A376-Y380 PolarHBondContact O-N 2.99Å; L377-Y380 HydrophobicContact CD2-CD2 4.33Å; L377-Y380 PolarHBondContact O-N 3.32Å; Y380-S383 PolarHBondContact O-N 3.43Å; Y380-Y384 WeakPolarHBondContact O-CD2 3.39Å; Y380-Y384 PolarHBondContact O-N 3.07Å; Y380-I411 HydrophobicContact CD1-CG1 4.19Å; Y380-I411 HydrophobicContact CD1-CG2 4.47Å; Y380-I411 HydrophobicContact CE1-CG2 4.36Å; Y380-H414 HydrophobicContact CE1-CB 3.65Å; Y380-T415 PolarHBondContact OH-N 3.42Å; Y380-T415 PolarHBondContact OH-OG1 3.39Å
381	A	95	Very high	92.1	Very high	30 Å²	30	37.8 Å²	37.8	25%	0.248	20%	0.2	C	C	.	.	H	α-helix	trans	-57.1	-54.6	178.4	0	0	0	0	0	110.9	L377 G378 S383 Y384 Y385	L377-A381 WeakPolarHBondContact O-CB 3.3Å; L377-A381 PolarHBondContact O-N 3.21Å; G378-A381 PolarHBondContact O-N 3.47Å; A381-S383 VanDerWaalsContact C-N 3.3Å; A381-S383 PolarHBondContact O-N 2.93Å; A381-Y384 PolarHBondContact O-N 3.29Å; A381-Y385 VanDerWaalsContact O-CD2 3.23Å; A381-Y385 WeakPolarHBondContact O-CD2 3.08Å; A381-Y385 PolarHBondContact O-N 3.43Å
382	I	94.3	Very high	92.4	Very high	3 Å²	3	39.4 Å²	39.4	2%	0.015	22%	0.218	C	C	.	.	H	α-helix	trans	-53.9	-49.2	177.4	-65.6	170.4	0	0	0	110.6	G378 Y384 Y385 S386 W533 C540 L541	G378-I382 PolarHBondContact O-N 2.83Å; G378-I382 VanDerWaalsContact O-N 3.11Å; I382-Y384 PolarHBondContact O-N 2.85Å; I382-Y385 PolarHBondContact O-N 3.23Å; I382-S386 PolarHBondContact O-N 3.45Å; I382-S386 PolarHBondContact O-OG 3.47Å; I382-W533 HydrophobicContact CG2-CH2 4.03Å; I382-C540 HydrophobicContact CD1-CB 3.64Å; I382-C540 HydrophobicContact CG1-CB 3.54Å; I382-L541 HydrophobicContact CD1-CB 4.29Å
383	S	95.6	Very high	92.3	Very high	5 Å²	5	40.7 Å²	40.7	4%	0.035	23%	0.232	C	C	.	.	H	α-helix	trans	-60.9	-42.5	-178.3	-56.4	0	0	0	0	112.5	Q379 Y380 A381 S386 I387	Q379-S383 WeakPolarHBondContact O-CB 3.32Å; Q379-S383 PolarHBondContact O-N 2.99Å; Q379-S383 PolarHBondContact O-OG 3.33Å; Y380-S383 PolarHBondContact O-N 3.43Å; A381-S383 VanDerWaalsContact C-N 3.3Å; A381-S383 PolarHBondContact O-N 2.93Å; S383-S386 PolarHBondContact O-N 2.8Å; S383-I387 WeakPolarHBondContact O-CD1 3.31Å; S383-I387 WeakPolarHBondContact O-CG1 3.45Å; S383-I387 PolarHBondContact O-N 3.42Å
384	Y	96	Very high	91.5	Very high	136 Å²	136	43.5 Å²	43.5	53%	0.533	25%	0.254	S	S	.	.	H	α-helix	trans	-67.9	-40.3	178	-78.6	-61.2	0	0	0	112.6	Y380 A381 I382 I387 V388 I411	Y380-Y384 WeakPolarHBondContact O-CD2 3.39Å; Y380-Y384 PolarHBondContact O-N 3.07Å; A381-Y384 PolarHBondContact O-N 3.29Å; I382-Y384 PolarHBondContact O-N 2.85Å; Y384-I387 HydrophobicContact CD1-CD1 4.4Å; Y384-I387 PolarHBondContact O-N 3.39Å; Y384-V388 WeakPolarHBondContact O-CG2 3.26Å; Y384-V388 PolarHBondContact O-N 2.81Å; Y384-I411 HydrophobicContact CD1-CD1 4.2Å; Y384-I411 HydrophobicContact CE1-CD1 3.9Å; Y384-I411 HydrophobicContact CE2-CD1 4.27Å
385	Y	95.1	Very high	90.4	Very high	99 Å²	99	46.1 Å²	46.1	39%	0.388	27%	0.266	S	S	.	.	H	α-helix	trans	-62.5	-44.6	173.8	-83.1	-79.4	0	0	0	111.2	A381 I382 I387 V388 A389 Y528 I536	A381-Y385 VanDerWaalsContact O-CD2 3.23Å; A381-Y385 WeakPolarHBondContact O-CD2 3.08Å; A381-Y385 PolarHBondContact O-N 3.43Å; I382-Y385 PolarHBondContact O-N 3.23Å; Y385-I387 PolarHBondContact O-N 3.38Å; Y385-V388 PolarHBondContact O-N 3.16Å; Y385-A389 PolarHBondContact O-N 3.25Å; Y385-Y528 AromaticContact CD1-CE1 4Å; Y385-Y528 HydrophobicContact CD1-CE1 4Å; Y385-Y528 AromaticContact CD1-CE2 3.97Å; Y385-Y528 HydrophobicContact CD1-CE2 3.97Å; Y385-Y528 AromaticContact CD1-CZ 3.58Å; Y385-Y528 HydrophobicContact CE1-CE1 4.38Å; Y385-Y528 WeakPolarHBondContact O-CE2 3.5Å; Y385-Y528 PolarHBondContact O-OH 2.82Å; Y385-I536 HydrophobicContact CD1-CD1 3.79Å; Y385-I536 HydrophobicContact CD2-CD1 4.17Å; Y385-I536 HydrophobicContact CD2-CG2 3.94Å; Y385-I536 HydrophobicContact CE1-CD1 3.67Å; Y385-I536 HydrophobicContact CE2-CD1 4.08Å; Y385-I536 HydrophobicContact CE2-CG1 4.49Å; Y385-I536 HydrophobicContact CE2-CG2 4.31Å; Y385-I536 HydrophobicContact CG-CD1 4.06Å; Y385-I536 HydrophobicContact CG-CG2 4.44Å
386	S	94	Very high	89.2	Confident	2 Å²	2	55.2 Å²	55.2	1%	0.014	31%	0.308	C	S	.	.	H	α-helix	trans	-61.5	-43	175.2	-65.7	0	0	0	0	112.3	I382 S383 V388 A389 V390 E524 W533	I382-S386 PolarHBondContact O-N 3.45Å; I382-S386 PolarHBondContact O-OG 3.47Å; S383-S386 PolarHBondContact O-N 2.8Å; S386-V388 VanDerWaalsContact C-N 3.34Å; S386-V388 PolarHBondContact O-N 3.07Å; S386-A389 PolarHBondContact O-N 3.48Å; S386-V390 WeakPolarHBondContact O-CG2 3.42Å; S386-V390 PolarHBondContact O-N 3.19Å; S386-E524 PolarHBondContact OG-OE1 2.91Å; S386-W533 WeakPolarHBondContact OG-CH2 3.47Å
387	I	94.4	Very high	88.8	Confident	30 Å²	30	59.7 Å²	59.7	15%	0.154	33%	0.332	C	S	.	.	H	α-helix	trans	-58.2	-46.6	175.9	-70.2	161	0	0	0	110.9	S383 Y384 Y385 V390 V391 L404 A407 L408 I411	S383-I387 WeakPolarHBondContact O-CD1 3.31Å; S383-I387 WeakPolarHBondContact O-CG1 3.45Å; S383-I387 PolarHBondContact O-N 3.42Å; Y384-I387 HydrophobicContact CD1-CD1 4.4Å; Y384-I387 PolarHBondContact O-N 3.39Å; Y385-I387 PolarHBondContact O-N 3.38Å; I387-V390 PolarHBondContact O-N 3.03Å; I387-V391 HydrophobicContact CG2-CG2 4.2Å; I387-V391 WeakPolarHBondContact O-CB 3.15Å; I387-V391 VanDerWaalsContact O-CG2 3.25Å; I387-V391 WeakPolarHBondContact O-CG2 3.33Å; I387-V391 PolarHBondContact O-N 2.8Å; I387-L404 HydrophobicContact CB-CD1 4.33Å; I387-L404 HydrophobicContact CG1-CD1 3.95Å; I387-L404 HydrophobicContact CG2-CD1 4.19Å; I387-A407 HydrophobicContact CD1-CB 4.27Å; I387-A407 HydrophobicContact CG1-CB 3.83Å; I387-L408 HydrophobicContact CD1-CD2 3.85Å; I387-L408 HydrophobicContact CD1-CG 4.42Å; I387-L408 HydrophobicContact CG1-CD2 4.44Å; I387-I411 HydrophobicContact CD1-CD1 3.7Å
388	V	94	Very high	88.6	Confident	73 Å²	73	60 Å²	60	44%	0.442	33%	0.333	S	S	.	.	H	α-helix	trans	-63.8	-44	179.5	171.4	0	0	0	0	110.8	Y384 Y385 S386 V390 V391 A392 F527 Y528	Y384-V388 WeakPolarHBondContact O-CG2 3.26Å; Y384-V388 PolarHBondContact O-N 2.81Å; Y385-V388 PolarHBondContact O-N 3.16Å; S386-V388 VanDerWaalsContact C-N 3.34Å; S386-V388 PolarHBondContact O-N 3.07Å; V388-V390 PolarHBondContact O-N 3.49Å; V388-V391 PolarHBondContact O-N 3.29Å; V388-A392 WeakPolarHBondContact O-CB 3.28Å; V388-A392 PolarHBondContact O-N 2.99Å; V388-F527 HydrophobicContact CG1-CE1 4.34Å; V388-Y528 WeakPolarHBondContact CB-OH 3.43Å; V388-Y528 WeakPolarHBondContact CG1-OH 3.24Å
389	A	91.7	Very high	88.4	Confident	2 Å²	2	60.5 Å²	60.5	2%	0.017	34%	0.335	C	S	.	.	H	α-helix	trans	-59.2	-45.3	177.3	0	0	0	0	0	112.3	Y385 S386 G393 E524 F527 Y528	Y385-A389 PolarHBondContact O-N 3.25Å; S386-A389 PolarHBondContact O-N 3.48Å; A389-G393 WeakPolarHBondContact O-CA 3.32Å; A389-G393 PolarHBondContact O-N 3.45Å; A389-E524 HydrophobicContact CB-CG 4.11Å; A389-F527 HydrophobicContact CB-CB 3.99Å; A389-F527 HydrophobicContact CB-CD1 3.86Å; A389-F527 HydrophobicContact CB-CG 3.97Å; A389-Y528 HydrophobicContact CB-CD2 4.39Å; A389-Y528 HydrophobicContact CB-CE2 3.81Å
390	V	91.5	Very high	88.2	Confident	7 Å²	7	60.3 Å²	60.3	4%	0.042	34%	0.336	C	S	.	.	H	α-helix	trans	-70.1	-43.4	-179.3	176.3	0	0	0	0	112.1	S386 I387 V388 A400 L404 V523	S386-V390 WeakPolarHBondContact O-CG2 3.42Å; S386-V390 PolarHBondContact O-N 3.19Å; I387-V390 PolarHBondContact O-N 3.03Å; V388-V390 PolarHBondContact O-N 3.49Å; V390-A400 HydrophobicContact CG1-CB 4.13Å; V390-L404 HydrophobicContact CB-CB 4.48Å; V390-L404 HydrophobicContact CG1-CB 4.02Å; V390-L404 HydrophobicContact CG1-CD2 4.29Å; V390-V523 HydrophobicContact CG2-CG1 3.89Å
391	V	90.9	Very high	87.9	Confident	100 Å²	100	60.6 Å²	60.6	61%	0.606	35%	0.348	S	S	*	.	H	α-helix	trans	-75.1	-38.3	-175.3	173.3	0	0	0	0	112.1	I387 V388 L404	I387-V391 HydrophobicContact CG2-CG2 4.2Å; I387-V391 WeakPolarHBondContact O-CB 3.15Å; I387-V391 VanDerWaalsContact O-CG2 3.25Å; I387-V391 WeakPolarHBondContact O-CG2 3.33Å; I387-V391 PolarHBondContact O-N 2.8Å; V388-V391 PolarHBondContact O-N 3.29Å; V391-L404 HydrophobicContact CG2-CD1 4.39Å
392	A	90.3	Very high	87.8	Confident	67 Å²	67	60.4 Å²	60.4	55%	0.554	34%	0.343	S	S	*	.	H	α-helix	trans	-87.3	-19.5	179.4	0	0	0	0	0	113.2	V388 F527	V388-A392 WeakPolarHBondContact O-CB 3.28Å; V388-A392 PolarHBondContact O-N 2.99Å; A392-F527 HydrophobicContact CB-CE2 3.91Å; A392-F527 HydrophobicContact CB-CZ 3.9Å
393	G	84.1	Confident	87.7	Confident	29 Å²	29	60.3 Å²	60.3	30%	0.299	34%	0.342	S	S	.	.	S	Bend	trans	-71.5	-169.5	170.5	0	0	0	0	0	112.6	A389 P395	A389-G393 WeakPolarHBondContact O-CA 3.32Å; A389-G393 PolarHBondContact O-N 3.45Å; G393-P395 WeakPolarHBondContact O-CD 3.13Å
394	T	72.1	Confident	87.6	Confident	143 Å²	143	62.2 Å²	62.2	88%	0.877	35%	0.352	S	S	*	.			trans	-96.8	95.8	174.3	50.9	0	0	0	0	110.2	Q396	T394-Q396 PolarHBondContact O-N 2.93Å
395	P	63.7	Low	87.6	Confident	86 Å²	86	58.8 Å²	58.8	56%	0.558	35%	0.345	S	S	*	.			trans	-80.8	106.4	-175.2	31.3	-35.3	0	0	0	111	G393	G393-P395 WeakPolarHBondContact O-CD 3.13Å
396	Q	65.6	Low	87.6	Confident	194 Å²	194	54.6 Å²	54.6	91%	0.907	33%	0.329	S	S	*	.			trans	-136.1	-4.5	165.7	-69.2	-169.5	-7.8	0	0	114.2	T394	T394-Q396 PolarHBondContact O-N 2.93Å
397	D	83.2	Confident	87.7	Confident	93 Å²	93	54.6 Å²	54.6	50%	0.497	33%	0.329	S	S	.	.			trans	-99.5	140.3	-174.8	-94.3	-55.3	0	0	0	113.7	R322 L399 A400 G401	R322-D397 IonicContact CZ-OD1 3.16Å; R322-D397 IonicContact NH1-OD1 3.67Å; R322-D397 PolarHBondContact NH1-OD1 3.02Å; R322-D397 IonicContact NH2-OD1 2.82Å; R322-D397 PolarHBondContact NH2-OD1 3.02Å; D397-L399 PolarHBondContact O-N 3.29Å; D397-L399 VanDerWaalsContact O-N 3.17Å; D397-A400 WeakPolarHBondContact O-CB 3.27Å; D397-A400 PolarHBondContact O-N 3.33Å; D397-A400 VanDerWaalsContact O-N 3.09Å; D397-G401 PolarHBondContact O-N 2.98Å
398	L	87.9	Confident	87.8	Confident	112 Å²	112	57.7 Å²	57.7	59%	0.586	35%	0.345	S	S	*	.	H	α-helix	trans	-51.5	-38.5	174.4	176	65.2	0	0	0	112.4	V326 G401 L402	V326-L398 HydrophobicContact CG2-CD2 4.47Å; L398-G401 PolarHBondContact O-N 2.85Å; L398-L402 HydrophobicContact CG-CD1 4.31Å; L398-L402 WeakPolarHBondContact O-CG 3.3Å; L398-L402 PolarHBondContact O-N 3.34Å
399	L	87.5	Confident	87.9	Confident	15 Å²	15	56.1 Å²	56.1	8%	0.079	33%	0.334	C	S	.	.	H	α-helix	trans	-67	-38.3	-178	-170.9	62.9	0	0	0	111.8	L325 Y329 D397 G401 L402 D403 N521	L325-L399 HydrophobicContact CB-CD1 3.94Å; L325-L399 HydrophobicContact CD1-CD2 4.1Å; Y329-L399 HydrophobicContact CD2-CD1 3.81Å; Y329-L399 HydrophobicContact CE2-CD1 3.94Å; D397-L399 PolarHBondContact O-N 3.29Å; D397-L399 VanDerWaalsContact O-N 3.17Å; L399-G401 VanDerWaalsContact C-N 3.33Å; L399-G401 PolarHBondContact O-N 3Å; L399-L402 PolarHBondContact O-N 3.35Å; L399-D403 WeakPolarHBondContact O-CB 3.19Å; L399-D403 PolarHBondContact O-N 3.28Å; L399-N521 WeakPolarHBondContact CD2-OD1 3.2Å
400	A	89.2	Confident	88.1	Confident	9 Å²	9	56.6 Å²	56.6	7%	0.074	34%	0.336	C	S	.	.	H	α-helix	trans	-64.7	-38	175.2	0	0	0	0	0	111.6	V390 D397 D403 L404 V523	V390-A400 HydrophobicContact CG1-CB 4.13Å; D397-A400 WeakPolarHBondContact O-CB 3.27Å; D397-A400 PolarHBondContact O-N 3.33Å; D397-A400 VanDerWaalsContact O-N 3.09Å; A400-D403 PolarHBondContact O-N 2.97Å; A400-L404 WeakPolarHBondContact O-CB 3.46Å; A400-L404 PolarHBondContact O-N 3.41Å; A400-V523 HydrophobicContact CB-CG2 4.28Å
401	G	90.9	Very high	88.3	Confident	37 Å²	37	57.5 Å²	57.5	38%	0.381	34%	0.341	S	S	.	.	H	α-helix	trans	-66.2	-40.7	174.4	0	0	0	0	0	113.4	D397 L398 L399 T405	D397-G401 PolarHBondContact O-N 2.98Å; L398-G401 PolarHBondContact O-N 2.85Å; L399-G401 VanDerWaalsContact C-N 3.33Å; L399-G401 PolarHBondContact O-N 3Å; G401-T405 WeakPolarHBondContact O-CB 3.3Å; G401-T405 PolarHBondContact O-N 3.39Å; G401-T405 PolarHBondContact O-OG1 3.47Å
402	L	92.7	Very high	88.6	Confident	27 Å²	27	54.1 Å²	54.1	14%	0.141	32%	0.323	C	S	.	.	H	α-helix	trans	-64.6	-44.4	174.2	-72.4	174.4	0	0	0	111.4	V326 Y329 I333 L398 L399 T405 H406	V326-L402 HydrophobicContact CB-CD1 4.33Å; V326-L402 HydrophobicContact CG1-CD1 4.11Å; V326-L402 HydrophobicContact CG2-CD1 4.08Å; Y329-L402 HydrophobicContact CG-CB 4.47Å; I333-L402 HydrophobicContact CD1-CB 4.4Å; I333-L402 HydrophobicContact CD1-CD2 3.75Å; L398-L402 HydrophobicContact CG-CD1 4.31Å; L398-L402 WeakPolarHBondContact O-CG 3.3Å; L398-L402 PolarHBondContact O-N 3.34Å; L399-L402 PolarHBondContact O-N 3.35Å; L402-T405 PolarHBondContact O-N 3.32Å; L402-H406 VanDerWaalsContact O-CB 3.31Å; L402-H406 WeakPolarHBondContact O-CB 3.42Å; L402-H406 PolarHBondContact O-N 3.05Å
403	D	91.8	Very high	88.9	Confident	1 Å²	1	50.9 Å²	50.9	1%	0.005	30%	0.297	C	S	.	.	H	α-helix	trans	-63.9	-44.4	179.3	-173.4	61.7	0	0	0	112	Y329 L399 A400 T405 H406 A407	Y329-D403 HydrophobicContact CE1-CB 4.35Å; Y329-D403 WeakPolarHBondContact CE1-OD1 3.11Å; Y329-D403 PolarHBondContact OH-OD1 3.41Å; L399-D403 WeakPolarHBondContact O-CB 3.19Å; L399-D403 PolarHBondContact O-N 3.28Å; A400-D403 PolarHBondContact O-N 2.97Å; D403-T405 VanDerWaalsContact C-N 3.35Å; D403-T405 PolarHBondContact O-N 3.36Å; D403-H406 WeakPolarHBondContact O-CB 3.37Å; D403-H406 PolarHBondContact O-N 3.08Å; D403-A407 WeakPolarHBondContact O-CB 3.42Å; D403-A407 PolarHBondContact O-N 3.36Å
404	L	93.8	Very high	89.4	Confident	45 Å²	45	49.5 Å²	49.5	24%	0.236	28%	0.282	C	S	.	.	H	α-helix	trans	-59.2	-44.9	173.6	179.4	62.3	0	0	0	112.2	I387 V390 V391 A400 H406 A407 L408	I387-L404 HydrophobicContact CB-CD1 4.33Å; I387-L404 HydrophobicContact CG1-CD1 3.95Å; I387-L404 HydrophobicContact CG2-CD1 4.19Å; V390-L404 HydrophobicContact CB-CB 4.48Å; V390-L404 HydrophobicContact CG1-CB 4.02Å; V390-L404 HydrophobicContact CG1-CD2 4.29Å; V391-L404 HydrophobicContact CG2-CD1 4.39Å; A400-L404 WeakPolarHBondContact O-CB 3.46Å; A400-L404 PolarHBondContact O-N 3.41Å; L404-H406 VanDerWaalsContact C-N 3.32Å; L404-H406 PolarHBondContact O-N 2.9Å; L404-A407 PolarHBondContact O-N 3.06Å; L404-L408 HydrophobicContact CD1-CD1 4.25Å; L404-L408 HydrophobicContact CD1-CG 4.38Å; L404-L408 HydrophobicContact CG-CD1 4.19Å; L404-L408 WeakPolarHBondContact O-CG 3.47Å; L404-L408 PolarHBondContact O-N 3.4Å
405	T	95.1	Very high	90.4	Very high	63 Å²	63	45.2 Å²	45.2	39%	0.387	26%	0.256	S	S	.	.	H	α-helix	trans	-63.4	-42.3	178.1	-56.8	0	0	0	0	110.9	I333 G401 L402 D403 L409	I333-T405 HydrophobicContact CD1-CG2 3.97Å; I333-T405 HydrophobicContact CG1-CG2 4.16Å; I333-T405 HydrophobicContact CG2-CG2 4.09Å; G401-T405 WeakPolarHBondContact O-CB 3.3Å; G401-T405 PolarHBondContact O-N 3.39Å; G401-T405 PolarHBondContact O-OG1 3.47Å; L402-T405 PolarHBondContact O-N 3.32Å; D403-T405 VanDerWaalsContact C-N 3.35Å; D403-T405 PolarHBondContact O-N 3.36Å; T405-L409 HydrophobicContact CG2-CD1 4.09Å; T405-L409 WeakPolarHBondContact O-CB 3.4Å; T405-L409 WeakPolarHBondContact O-CG 3.39Å; T405-L409 PolarHBondContact O-N 2.99Å
406	H	95.1	Very high	91.9	Very high	12 Å²	12	44.4 Å²	44.4	6%	0.056	24%	0.244	C	C	.	.	H	α-helix	trans	-61.7	-48.6	175.8	173.9	-96.8	0	0	0	111.6	Y329 I333 L402 D403 L404 L408 L409 M410	Y329-H406 HydrophobicContact CD1-CB 3.8Å; Y329-H406 AromaticContact CD1-CG 3.82Å; Y329-H406 HydrophobicContact CE1-CB 4.12Å; Y329-H406 AromaticContact CE1-CG 3.96Å; Y329-H406 AromaticContact CE1-ND1 3.91Å; I333-H406 HydrophobicContact CG1-CB 4.12Å; L402-H406 VanDerWaalsContact O-CB 3.31Å; L402-H406 WeakPolarHBondContact O-CB 3.42Å; L402-H406 PolarHBondContact O-N 3.05Å; D403-H406 WeakPolarHBondContact O-CB 3.37Å; D403-H406 PolarHBondContact O-N 3.08Å; L404-H406 VanDerWaalsContact C-N 3.32Å; L404-H406 PolarHBondContact O-N 2.9Å; H406-L408 PolarHBondContact O-N 2.88Å; H406-L409 PolarHBondContact O-N 3.09Å; H406-M410 WeakPolarHBondContact O-CB 3.19Å; H406-M410 VanDerWaalsContact O-CG 3.25Å; H406-M410 WeakPolarHBondContact O-CG 3.47Å; H406-M410 PolarHBondContact O-N 3.37Å
407	A	95.6	Very high	93.3	Very high	1 Å²	1	35.2 Å²	35.2	1%	0.008	20%	0.201	C	C	.	.	H	α-helix	trans	-60.9	-43.5	179.1	0	0	0	0	0	112.5	I387 D403 L404 M410 I411	I387-A407 HydrophobicContact CD1-CB 4.27Å; I387-A407 HydrophobicContact CG1-CB 3.83Å; D403-A407 WeakPolarHBondContact O-CB 3.42Å; D403-A407 PolarHBondContact O-N 3.36Å; L404-A407 PolarHBondContact O-N 3.06Å; A407-M410 PolarHBondContact O-N 2.89Å; A407-I411 WeakPolarHBondContact O-CG1 3.5Å; A407-I411 PolarHBondContact O-N 2.94Å
408	L	96.8	Very high	93.8	Very high	95 Å²	95	30.9 Å²	30.9	50%	0.497	18%	0.178	S	C	.	.	H	α-helix	trans	-64.5	-43.9	176.2	-69.7	172	0	0	0	112.1	I387 L404 H406 I411 A412	I387-L408 HydrophobicContact CD1-CD2 3.85Å; I387-L408 HydrophobicContact CD1-CG 4.42Å; I387-L408 HydrophobicContact CG1-CD2 4.44Å; L404-L408 HydrophobicContact CD1-CD1 4.25Å; L404-L408 HydrophobicContact CD1-CG 4.38Å; L404-L408 HydrophobicContact CG-CD1 4.19Å; L404-L408 WeakPolarHBondContact O-CG 3.47Å; L404-L408 PolarHBondContact O-N 3.4Å; H406-L408 PolarHBondContact O-N 2.88Å; L408-I411 PolarHBondContact O-N 3.49Å; L408-A412 PolarHBondContact O-N 3.39Å; L408-A412 VanDerWaalsContact O-N 3.08Å
409	L	96.8	Very high	94	Very high	40 Å²	40	29 Å²	29	21%	0.209	17%	0.167	C	C	.	.	H	α-helix	trans	-66.9	-36.1	176.5	-80.4	172.9	0	0	0	112.3	I333 L336 T405 H406 I411 A412 Q413	I333-L409 HydrophobicContact CB-CD1 4.16Å; I333-L409 HydrophobicContact CG1-CD1 4.32Å; I333-L409 HydrophobicContact CG2-CD1 3.66Å; L336-L409 HydrophobicContact CB-CB 4.08Å; L336-L409 HydrophobicContact CD1-CB 4.39Å; T405-L409 HydrophobicContact CG2-CD1 4.09Å; T405-L409 WeakPolarHBondContact O-CB 3.4Å; T405-L409 WeakPolarHBondContact O-CG 3.39Å; T405-L409 PolarHBondContact O-N 2.99Å; H406-L409 PolarHBondContact O-N 3.09Å; L409-I411 VanDerWaalsContact C-N 3.34Å; L409-I411 PolarHBondContact O-N 2.95Å; L409-A412 PolarHBondContact O-N 3.34Å; L409-Q413 WeakPolarHBondContact O-CB 3.39Å; L409-Q413 PolarHBondContact O-N 3.18Å
410	M	95.6	Very high	94.2	Very high	13 Å²	13	28.3 Å²	28.3	6%	0.064	16%	0.164	C	C	.	.	H	α-helix	trans	-58.2	-46.6	174.6	-80.5	-69.8	-82.9	0	0	111.1	L336 Q379 H406 A407 Q413 H414	L336-M410 HydrophobicContact CD1-CG 3.63Å; L336-M410 HydrophobicContact CD1-SD 3.51Å; L336-M410 VanDerWaalsContact CD1-SD 3.51Å; L336-M410 HydrophobicContact CD2-SD 3.61Å; L336-M410 HydrophobicContact CG-SD 4.21Å; Q379-M410 HydrophobicContact CB-CE 4.33Å; Q379-M410 HydrophobicContact CG-CE 4.29Å; H406-M410 WeakPolarHBondContact O-CB 3.19Å; H406-M410 VanDerWaalsContact O-CG 3.25Å; H406-M410 WeakPolarHBondContact O-CG 3.47Å; H406-M410 PolarHBondContact O-N 3.37Å; A407-M410 PolarHBondContact O-N 2.89Å; M410-Q413 PolarHBondContact O-N 3.36Å; M410-H414 PolarHBondContact O-N 2.78Å; M410-H414 PolarHBondContact O-ND1 2.88Å
411	I	96.8	Very high	94.2	Very high	26 Å²	26	27.9 Å²	27.9	13%	0.133	16%	0.16	C	C	.	.	H	α-helix	trans	-61.8	-49.4	176.9	-64.9	168	0	0	0	110.8	Y380 Y384 I387 A407 L408 L409 Q413 T415	Y380-I411 HydrophobicContact CD1-CG1 4.19Å; Y380-I411 HydrophobicContact CD1-CG2 4.47Å; Y380-I411 HydrophobicContact CE1-CG2 4.36Å; Y384-I411 HydrophobicContact CD1-CD1 4.2Å; Y384-I411 HydrophobicContact CE1-CD1 3.9Å; Y384-I411 HydrophobicContact CE2-CD1 4.27Å; I387-I411 HydrophobicContact CD1-CD1 3.7Å; A407-I411 WeakPolarHBondContact O-CG1 3.5Å; A407-I411 PolarHBondContact O-N 2.94Å; L408-I411 PolarHBondContact O-N 3.49Å; L409-I411 VanDerWaalsContact C-N 3.34Å; L409-I411 PolarHBondContact O-N 2.95Å; I411-Q413 PolarHBondContact O-N 3.27Å; I411-T415 WeakPolarHBondContact O-CB 3.45Å; I411-T415 PolarHBondContact O-N 2.89Å; I411-T415 PolarHBondContact O-OG1 2.86Å
412	A	96.2	Very high	94.1	Very high	28 Å²	28	28 Å²	28	23%	0.231	15%	0.152	C	C	.	.	H	α-helix	trans	-59.4	-48.8	179.6	0	0	0	0	0	111.2	T340 L408 L409 T415 F416	T340-A412 HydrophobicContact CG2-CB 4.3Å; L408-A412 PolarHBondContact O-N 3.39Å; L408-A412 VanDerWaalsContact O-N 3.08Å; L409-A412 PolarHBondContact O-N 3.34Å; A412-T415 PolarHBondContact O-N 3Å; A412-F416 HydrophobicContact CB-CD2 4.37Å; A412-F416 HydrophobicContact CB-CE2 4.39Å; A412-F416 WeakPolarHBondContact O-CD2 3.48Å; A412-F416 PolarHBondContact O-N 3.37Å
413	Q	96.4	Very high	93.7	Very high	0 Å²	0	28.3 Å²	28.3	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-59.5	-51.8	-177	-172.7	-79.8	-58.4	0	0	111.8	L336 T339 T340 L409 M410 I411 T415 F416 Q417 R548	L336-Q413 HydrophobicContact CB-CB 4.48Å; L336-Q413 HydrophobicContact CB-CG 4.41Å; L336-Q413 HydrophobicContact CD2-CB 4.12Å; L336-Q413 HydrophobicContact CD2-CG 3.72Å; T339-Q413 VanDerWaalsContact OG1-CG 3.28Å; T339-Q413 WeakPolarHBondContact OG1-CG 3.34Å; T340-Q413 WeakPolarHBondContact OG1-CA 3.06Å; T340-Q413 VanDerWaalsContact OG1-CB 3.26Å; T340-Q413 WeakPolarHBondContact OG1-CB 3.25Å; L409-Q413 WeakPolarHBondContact O-CB 3.39Å; L409-Q413 PolarHBondContact O-N 3.18Å; M410-Q413 PolarHBondContact O-N 3.36Å; I411-Q413 PolarHBondContact O-N 3.27Å; Q413-T415 VanDerWaalsContact C-N 3.32Å; Q413-T415 PolarHBondContact O-N 3Å; Q413-F416 PolarHBondContact O-N 3.27Å; Q413-Q417 WeakPolarHBondContact O-CB 3.32Å; Q413-Q417 PolarHBondContact O-N 3.3Å; Q413-R548 VanDerWaalsContact OE1-CZ 3.25Å
414	H	94.8	Very high	93.2	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-63.8	-38	178.2	-73.2	77.4	0	0	0	111.6	Y380 M410 N418 Y547 R548	Y380-H414 HydrophobicContact CE1-CB 3.65Å; M410-H414 PolarHBondContact O-N 2.78Å; M410-H414 PolarHBondContact O-ND1 2.88Å; H414-N418 WeakPolarHBondContact O-CB 3.02Å; H414-N418 PolarHBondContact O-N 3.4Å; H414-N418 PolarHBondContact O-ND2 2.96Å; H414-N418 PolarHBondContact O-OD1 3.47Å; H414-Y547 AromaticContact CD2-CD1 3.42Å; H414-Y547 VanDerWaalsContact CD2-CD1 3.42Å; H414-Y547 WeakPolarHBondContact CD2-CD1 3.5Å; H414-Y547 AromaticContact CD2-CE1 3.19Å; H414-Y547 WeakPolarHBondContact CD2-CE1 3.22Å; H414-Y547 AromaticContact CD2-CG 3.98Å; H414-Y547 AromaticContact CD2-CZ 3.54Å; H414-Y547 AromaticContact NE2-CD1 3.47Å; H414-Y547 WeakPolarHBondContact NE2-CD1 3.43Å; H414-Y547 AromaticContact NE2-CE1 3.57Å; H414-R548 PolarHBondContact CE1-NH2 2.92Å
415	T	94.2	Very high	92.5	Very high	53 Å²	53	27.6 Å²	27.6	33%	0.325	15%	0.149	S	C	.	.	H	α-helix	trans	-63.2	-53.1	178.5	-58.8	0	0	0	0	111.2	Y380 I411 A412 Q413 N418 I419	Y380-T415 PolarHBondContact OH-N 3.42Å; Y380-T415 PolarHBondContact OH-OG1 3.39Å; I411-T415 WeakPolarHBondContact O-CB 3.45Å; I411-T415 PolarHBondContact O-N 2.89Å; I411-T415 PolarHBondContact O-OG1 2.86Å; A412-T415 PolarHBondContact O-N 3Å; Q413-T415 VanDerWaalsContact C-N 3.32Å; Q413-T415 PolarHBondContact O-N 3Å; T415-N418 PolarHBondContact O-N 2.93Å; T415-I419 HydrophobicContact CG2-CD1 4.15Å; T415-I419 VanDerWaalsContact O-CG1 3.32Å; T415-I419 WeakPolarHBondContact O-CG1 3.39Å; T415-I419 PolarHBondContact O-N 2.98Å; T415-I419 VanDerWaalsContact O-N 3.08Å
416	F	94.8	Very high	91.6	Very high	69 Å²	69	26.4 Å²	26.4	30%	0.303	14%	0.139	S	C	.	.	H	α-helix	trans	-70.2	-36.3	-178	-71.8	-64.2	0	0	0	112.6	T340 L344 A412 Q413 I419 F420	T340-F416 HydrophobicContact CG2-CB 4.49Å; T340-F416 HydrophobicContact CG2-CD2 3.55Å; T340-F416 HydrophobicContact CG2-CE2 4.18Å; T340-F416 HydrophobicContact CG2-CG 4.35Å; L344-F416 HydrophobicContact CD1-CD1 3.93Å; L344-F416 HydrophobicContact CD1-CE1 3.82Å; A412-F416 HydrophobicContact CB-CD2 4.37Å; A412-F416 HydrophobicContact CB-CE2 4.39Å; A412-F416 WeakPolarHBondContact O-CD2 3.48Å; A412-F416 PolarHBondContact O-N 3.37Å; Q413-F416 PolarHBondContact O-N 3.27Å; F416-I419 PolarHBondContact O-N 3.31Å; F416-F420 WeakPolarHBondContact O-CB 3.18Å; F416-F420 PolarHBondContact O-N 3.02Å
417	Q	95.1	Very high	90.5	Very high	0 Å²	0	27.1 Å²	27.1	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-66.3	-39.9	174.6	-172.9	-179.2	5.7	0	0	111.6	Q413 F420 I421 N504	Q413-Q417 WeakPolarHBondContact O-CB 3.32Å; Q413-Q417 PolarHBondContact O-N 3.3Å; Q417-F420 PolarHBondContact O-N 3.43Å; Q417-I421 HydrophobicContact CG-CD1 3.76Å; Q417-I421 HydrophobicContact CG-CG1 4.25Å; Q417-I421 WeakPolarHBondContact O-CB 3.5Å; Q417-I421 WeakPolarHBondContact O-CG1 3.4Å; Q417-I421 PolarHBondContact O-N 2.63Å; Q417-N504 PolarHBondContact NE2-ND2 3.12Å; Q417-N504 PolarHBondContact NE2-OD1 2.77Å; Q417-N504 PolarHBondContact OE1-OD1 3.17Å
418	N	93.8	Very high	88.7	Confident	3 Å²	3	27.5 Å²	27.5	2%	0.016	15%	0.145	C	C	.	.	H	α-helix	trans	-62.2	-45.8	175.8	-75.7	-9.6	0	0	0	111.7	L372 H414 T415 F420 I421 I422 Y547	L372-N418 HydrophobicContact CD2-CB 4.36Å; L372-N418 WeakPolarHBondContact CD2-OD1 3.32Å; L372-N418 WeakPolarHBondContact CG-OD1 3.42Å; H414-N418 WeakPolarHBondContact O-CB 3.02Å; H414-N418 PolarHBondContact O-N 3.4Å; H414-N418 PolarHBondContact O-ND2 2.96Å; H414-N418 PolarHBondContact O-OD1 3.47Å; T415-N418 PolarHBondContact O-N 2.93Å; N418-F420 VanDerWaalsContact C-N 3.31Å; N418-F420 PolarHBondContact O-N 2.68Å; N418-I421 PolarHBondContact O-N 3.39Å; N418-I422 HydrophobicContact CB-CD1 4.38Å; N418-I422 VanDerWaalsContact O-CB 3.28Å; N418-I422 WeakPolarHBondContact O-CB 3.48Å; N418-I422 WeakPolarHBondContact O-CD1 3.46Å; N418-I422 WeakPolarHBondContact O-CG1 3.43Å; N418-I422 PolarHBondContact O-N 2.89Å; N418-Y547 WeakPolarHBondContact OD1-CE2 3.17Å; N418-Y547 VanDerWaalsContact OD1-CZ 3.26Å; N418-Y547 PolarHBondContact OD1-OH 2.8Å
419	I	91.1	Very high	86.9	Confident	72 Å²	72	27.7 Å²	27.7	37%	0.369	15%	0.153	S	C	.	.	H	α-helix	trans	-56.9	-49.5	175.3	-68.2	165.7	0	0	0	110	T415 F416 I422 E423	T415-I419 HydrophobicContact CG2-CD1 4.15Å; T415-I419 VanDerWaalsContact O-CG1 3.32Å; T415-I419 WeakPolarHBondContact O-CG1 3.39Å; T415-I419 PolarHBondContact O-N 2.98Å; T415-I419 VanDerWaalsContact O-N 3.08Å; F416-I419 PolarHBondContact O-N 3.31Å; I419-I422 PolarHBondContact O-N 2.67Å; I419-E423 VanDerWaalsContact O-CB 3.27Å; I419-E423 WeakPolarHBondContact O-CB 3.22Å; I419-E423 PolarHBondContact O-N 3.22Å
420	F	91.7	Very high	84.9	Confident	0 Å²	0	28.1 Å²	28.1	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-57.2	-53.6	178.8	176.7	-106	0	0	0	112	S347 Y350 F416 Q417 N418 E423 S424 L493 I496 L500 L555	S347-F420 WeakPolarHBondContact OG-CB 3.41Å; Y350-F420 AromaticContact CD2-CD2 3.89Å; Y350-F420 HydrophobicContact CD2-CD2 3.89Å; Y350-F420 AromaticContact CD2-CE2 3.66Å; Y350-F420 HydrophobicContact CD2-CE2 3.66Å; Y350-F420 AromaticContact CE2-CD2 3.83Å; Y350-F420 HydrophobicContact CE2-CD2 3.83Å; Y350-F420 AromaticContact CE2-CE2 3.25Å; Y350-F420 HydrophobicContact CE2-CE2 3.25Å; Y350-F420 AromaticContact CE2-CZ 3.85Å; Y350-F420 HydrophobicContact CE2-CZ 3.85Å; F416-F420 WeakPolarHBondContact O-CB 3.18Å; F416-F420 PolarHBondContact O-N 3.02Å; Q417-F420 PolarHBondContact O-N 3.43Å; N418-F420 VanDerWaalsContact C-N 3.31Å; N418-F420 PolarHBondContact O-N 2.68Å; F420-E423 PolarHBondContact O-N 3.42Å; F420-S424 WeakPolarHBondContact O-CB 3.24Å; F420-S424 PolarHBondContact O-N 3.33Å; F420-S424 PolarHBondContact O-OG 3.49Å; F420-L493 HydrophobicContact CE2-CD2 4.29Å; F420-I496 HydrophobicContact CE1-CG2 4.2Å; F420-I496 HydrophobicContact CE2-CG2 4.11Å; F420-I496 HydrophobicContact CZ-CG2 3.63Å; F420-L500 HydrophobicContact CD1-CD1 3.85Å; F420-L500 HydrophobicContact CE1-CD1 3.71Å; F420-L500 HydrophobicContact CZ-CD1 4.47Å; F420-L555 HydrophobicContact CD1-CD2 4.11Å; F420-L555 HydrophobicContact CE1-CD2 3.73Å
421	I	90.3	Very high	82.5	Confident	0 Å²	0	38.8 Å²	38.8	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-61.8	-48	-178	-70.7	173.1	0	0	0	111	L372 Q417 N418 E423 S424 L425 A551 S554 L555	L372-I421 HydrophobicContact CD2-CB 4.13Å; L372-I421 HydrophobicContact CD2-CD1 4.48Å; L372-I421 HydrophobicContact CD2-CG2 3.86Å; Q417-I421 HydrophobicContact CG-CD1 3.76Å; Q417-I421 HydrophobicContact CG-CG1 4.25Å; Q417-I421 WeakPolarHBondContact O-CB 3.5Å; Q417-I421 WeakPolarHBondContact O-CG1 3.4Å; Q417-I421 PolarHBondContact O-N 2.63Å; N418-I421 PolarHBondContact O-N 3.39Å; I421-E423 PolarHBondContact O-N 2.91Å; I421-S424 WeakPolarHBondContact O-CB 3.2Å; I421-S424 PolarHBondContact O-N 3.5Å; I421-L425 HydrophobicContact CG2-CD1 3.72Å; I421-L425 HydrophobicContact CG2-CG 4.28Å; I421-L425 WeakPolarHBondContact O-CG 3.47Å; I421-L425 PolarHBondContact O-N 3.43Å; I421-A551 HydrophobicContact CD1-CB 3.93Å; I421-S554 VanDerWaalsContact CG2-CB 3.48Å; I421-L555 HydrophobicContact CD1-CD2 4.42Å; I421-L555 HydrophobicContact CD1-CG 4.2Å; I421-L555 HydrophobicContact CG1-CD2 4.05Å; I421-L555 HydrophobicContact CG1-CG 4.31Å
422	I	87.1	Confident	79.8	Confident	40 Å²	40	41.8 Å²	41.8	21%	0.205	23%	0.226	C	C	.	.	H	α-helix	trans	-62.9	-46.2	-177.4	-65.7	166.3	0	0	0	110.2	V369 L372 N418 I419 S424 L425 H426	V369-I422 HydrophobicContact CG1-CD1 3.87Å; V369-I422 HydrophobicContact CG1-CG1 4.18Å; V369-I422 HydrophobicContact CG2-CG1 4.17Å; V369-I422 HydrophobicContact CG2-CG2 4.12Å; L372-I422 HydrophobicContact CD2-CG1 4.13Å; N418-I422 HydrophobicContact CB-CD1 4.38Å; N418-I422 VanDerWaalsContact O-CB 3.28Å; N418-I422 WeakPolarHBondContact O-CB 3.48Å; N418-I422 WeakPolarHBondContact O-CD1 3.46Å; N418-I422 WeakPolarHBondContact O-CG1 3.43Å; N418-I422 PolarHBondContact O-N 2.89Å; I419-I422 PolarHBondContact O-N 2.67Å; I422-S424 VanDerWaalsContact C-N 3.29Å; I422-S424 PolarHBondContact O-N 3.3Å; I422-L425 PolarHBondContact O-N 3.17Å; I422-H426 PolarHBondContact O-N 2.97Å; I422-H426 PolarHBondContact O-ND1 3.14Å
423	E	84.9	Confident	76.8	Confident	34 Å²	34	47.7 Å²	47.7	16%	0.159	25%	0.249	C	C	.	.	H	α-helix	trans	-63.4	-37.8	177.8	-170.2	175.1	163.9	0	0	111.4	I419 F420 I421 H426 R427	I419-E423 VanDerWaalsContact O-CB 3.27Å; I419-E423 WeakPolarHBondContact O-CB 3.22Å; I419-E423 PolarHBondContact O-N 3.22Å; F420-E423 PolarHBondContact O-N 3.42Å; I421-E423 PolarHBondContact O-N 2.91Å; E423-H426 PolarHBondContact O-N 3.42Å; E423-R427 WeakPolarHBondContact O-CG 3.33Å; E423-R427 IonicContact OE1-CZ 3.76Å; E423-R427 IonicContact OE1-NH2 2.79Å; E423-R427 PolarHBondContact OE1-NH2 3.43Å
424	S	82.2	Confident	73.8	Confident	8 Å²	8	53.7 Å²	53.7	6%	0.056	29%	0.287	C	S	.	.	H	α-helix	trans	-65.2	-45.3	177.8	-54	0	0	0	0	112.4	Y350 F420 I421 I422 H426	Y350-S424 WeakPolarHBondContact CE2-OG 3.34Å; Y350-S424 PolarHBondContact OH-OG 3.24Å; F420-S424 WeakPolarHBondContact O-CB 3.24Å; F420-S424 PolarHBondContact O-N 3.33Å; F420-S424 PolarHBondContact O-OG 3.49Å; I421-S424 WeakPolarHBondContact O-CB 3.2Å; I421-S424 PolarHBondContact O-N 3.5Å; I422-S424 VanDerWaalsContact C-N 3.29Å; I422-S424 PolarHBondContact O-N 3.3Å; S424-H426 VanDerWaalsContact C-N 3.28Å; S424-H426 PolarHBondContact O-N 3.18Å
425	L	78.8	Confident	70.8	Confident	22 Å²	22	62.2 Å²	62.2	12%	0.115	33%	0.327	C	S	.	.	H	α-helix	trans	-72.2	-17	-178.5	-68.5	174.1	0	0	0	113.6	R365 I421 I422 E557 V558	R365-L425 WeakPolarHBondContact CD-O 3.4Å; I421-L425 HydrophobicContact CG2-CD1 3.72Å; I421-L425 HydrophobicContact CG2-CG 4.28Å; I421-L425 WeakPolarHBondContact O-CG 3.47Å; I421-L425 PolarHBondContact O-N 3.43Å; I422-L425 PolarHBondContact O-N 3.17Å; L425-E557 HydrophobicContact CD2-CB 4.44Å; L425-E557 HydrophobicContact CD2-CG 4.17Å; L425-V558 HydrophobicContact CD2-CG2 4.12Å; L425-V558 HydrophobicContact CG-CG2 4.38Å
426	H	75.9	Confident	67.8	Low	38 Å²	38	65.5 Å²	65.5	18%	0.176	35%	0.352	C	S	.	.	T	Hydrogen-bonded Turn	trans	-94.8	2.5	-178.6	-77.5	68.9	0	0	0	114.5	M357 D358 R365 I422 E423 S424	M357-H426 HydrophobicContact CE-CB 3.56Å; D358-H426 PolarHBondContact N-O 3.41Å; R365-H426 PolarHBondContact NE-CD2 3.28Å; R365-H426 PolarHBondContact NE-NE2 3.33Å; R365-H426 PolarHBondContact NH2-CD2 3.13Å; R365-H426 VanDerWaalsContact NH2-CD2 3.26Å; I422-H426 PolarHBondContact O-N 2.97Å; I422-H426 PolarHBondContact O-ND1 3.14Å; E423-H426 PolarHBondContact O-N 3.42Å; S424-H426 VanDerWaalsContact C-N 3.28Å; S424-H426 PolarHBondContact O-N 3.18Å
427	R	71	Confident	64.6	Low	27 Å²	27	67.3 Å²	67.3	10%	0.102	37%	0.369	C	S	.	.	B	Isolated β-bridge	trans	-87.6	141.9	-180	-75.4	170.9	179.7	-109.2	-13.9	111.8	Y350 D353 M357 E423	Y350-R427 VanDerWaalsContact CB-NH2 3.31Å; Y350-R427 PolarHBondContact O-NH1 2.99Å; Y350-R427 PolarHBondContact O-NH2 2.99Å; D353-R427 PolarHBondContact O-NH1 3.27Å; D353-R427 VanDerWaalsContact O-NH1 3.09Å; D353-R427 IonicContact OD2-NH1 2.68Å; M357-R427 HydrophobicContact SD-CG 4.05Å; E423-R427 WeakPolarHBondContact O-CG 3.33Å; E423-R427 IonicContact OE1-CZ 3.76Å; E423-R427 IonicContact OE1-NH2 2.79Å; E423-R427 PolarHBondContact OE1-NH2 3.43Å
428	G	58.7	Low	61.6	Low	9 Å²	9	73.6 Å²	73.6	9%	0.093	41%	0.41	C	S	.	.	P	Polyproline II helix	trans	-64.6	152.8	174	0	0	0	0	0	113.6	A356 D358	A356-G428 PolarHBondContact O-N 3.34Å; D358-G428 WeakPolarHBondContact OD1-CA 3.28Å; D358-G428 VanDerWaalsContact OD2-CA 3.3Å; D358-G428 WeakPolarHBondContact OD2-CA 3.3Å
429	P	58.7	Low	58.5	Low	100 Å²	100	79 Å²	79	65%	0.649	44%	0.443	S	S	*	.	P	Polyproline II helix	trans	-56	149.5	176.7	23.4	-32.6	0	0	0	110	R431	P429-R431 PolarHBondContact O-N 3.2Å; P429-R431 VanDerWaalsContact O-N 3.1Å
430	P	55.5	Low	55.5	Low	48 Å²	48	85.5 Å²	85.5	31%	0.312	47%	0.469	S	S	.	.	P	Polyproline II helix	trans	-51.2	123.6	174.4	-23.6	32.5	0	0	0	110.1	A432	P430-A432 PolarHBondContact O-N 2.98Å
431	R	45.5	Very low	52.4	Low	238 Å²	238	94.3 Å²	94.3	90%	0.898	51%	0.51	S	S	*	.	P	Polyproline II helix	trans	-58.5	117.8	174.1	-154.2	174.9	-170.7	172.4	1.4	106.6	P429 E433	P429-R431 PolarHBondContact O-N 3.2Å; P429-R431 VanDerWaalsContact O-N 3.1Å; R431-E433 PolarHBondContact O-N 3.26Å; R431-E433 VanDerWaalsContact O-N 3.16Å
432	A	38.6	Very low	49.4	Very low	89 Å²	89	100.3 Å²	100.3	74%	0.736	55%	0.549	S	S	*	.	P	Polyproline II helix	trans	-57.1	122.6	171	0	0	0	0	0	106.6	P430	P430-A432 PolarHBondContact O-N 2.98Å
433	E	34.7	Very low	46.7	Very low	152 Å²	152	104.4 Å²	104.4	71%	0.71	58%	0.579	S	S	*	*	P	Polyproline II helix	trans	-58.3	127.7	168.2	-71.1	-169.1	167	0	0	106.8	R431 H435	R431-E433 PolarHBondContact O-N 3.26Å; R431-E433 VanDerWaalsContact O-N 3.16Å; E433-H435 PolarHBondContact O-N 3.42Å
434	P	31.8	Very low	43.9	Very low	125 Å²	125	111.2 Å²	111.2	81%	0.812	61%	0.611	S	S	*	*			trans	-61.3	110.3	173.3	23.1	-28.6	0	0	0	107	S436	P434-S436 PolarHBondContact O-N 3.29Å; P434-S436 VanDerWaalsContact O-N 3.12Å
435	H	32.4	Very low	41.2	Very low	179 Å²	179	117.6 Å²	117.6	83%	0.829	65%	0.645	S	S	*	*			trans	-50.5	123.5	160.5	-76.5	-60.5	0	0	0	106.7	E433 T437	E433-H435 PolarHBondContact O-N 3.42Å; H435-T437 VanDerWaalsContact C-N 3.3Å; H435-T437 PolarHBondContact O-N 3.22Å
436	S	30.4	Very low	38.8	Very low	122 Å²	122	125.1 Å²	125.1	85%	0.853	68%	0.684	S	S	*	*			trans	-58.1	86.7	-177.8	41.2	0	0	0	0	111.3	P434	P434-S436 PolarHBondContact O-N 3.29Å; P434-S436 VanDerWaalsContact O-N 3.12Å
437	T	27.9	Very low	36.5	Very low	107 Å²	107	128.4 Å²	128.4	66%	0.656	71%	0.707	S	S	*	*			trans	-88.5	118.5	155.1	51.5	0	0	0	0	107	H435 T439	H435-T437 VanDerWaalsContact C-N 3.3Å; H435-T437 PolarHBondContact O-N 3.22Å; T437-T439 VanDerWaalsContact C-N 3.33Å; T437-T439 PolarHBondContact O-N 3.35Å
438	P	33.5	Very low	34.5	Very low	133 Å²	133	135.8 Å²	135.8	86%	0.864	74%	0.74	S	S	*	*			trans	-75.6	89.1	-178.2	30.6	-31.4	0	0	0	108.8
439	T	27.2	Very low	33.1	Very low	116 Å²	116	140.8 Å²	140.8	71%	0.712	77%	0.769	S	S	*	*			trans	-109.6	113.7	173.4	-26.9	0	0	0	0	108	T437 E441	T437-T439 VanDerWaalsContact C-N 3.33Å; T437-T439 PolarHBondContact O-N 3.35Å; T439-E441 PolarHBondContact O-N 2.76Å
440	K	28.6	Very low	31.8	Very low	208 Å²	208	142.9 Å²	142.9	90%	0.904	78%	0.775	S	S	*	*	P	Polyproline II helix	trans	-52.5	122.2	179.3	-66.3	173.8	176.2	177.2	0	110.6
441	E	27.3	Very low	30.6	Very low	185 Å²	185	147 Å²	147	86%	0.864	79%	0.793	S	S	*	*	P	Polyproline II helix	trans	-94.8	133.5	163.1	-76.4	-171.3	163.8	0	0	110.2	T439	T439-E441 PolarHBondContact O-N 2.76Å
442	P	27.8	Very low	29.8	Very low	126 Å²	126	142.5 Å²	142.5	82%	0.818	79%	0.787	S	S	*	*	P	Polyproline II helix	trans	-77.5	132	164.8	9.2	5.9	0	0	0	110.4
443	C	28.4	Very low	29.4	Very low	126 Å²	126	142.6 Å²	142.6	85%	0.851	79%	0.788	S	S	*	*	P	Polyproline II helix	trans	-55.9	138.2	173.2	-67.3	0	0	0	0	112.7
444	Q	27.4	Very low	29.1	Very low	177 Å²	177	145.2 Å²	145.2	83%	0.827	80%	0.797	S	S	*	*			trans	-156.7	118.1	144.5	-110	161.1	14.7	0	0	112.8
445	N	24.8	Very low	29.1	Very low	142 Å²	142	147.7 Å²	147.7	76%	0.759	80%	0.798	S	S	*	*			trans	73.4	92.7	143	-58.2	-9.7	0	0	0	120.2
446	L	29.4	Very low	28.9	Very low	181 Å²	181	146.1 Å²	146.1	95%	0.948	80%	0.801	S	S	*	*			trans	-97.4	132.5	148.5	-131.2	88.7	0	0	0	108.5
447	T	26.8	Very low	28.8	Very low	106 Å²	106	148.3 Å²	148.3	65%	0.65	80%	0.802	S	S	*	*			trans	-112.3	152.5	174.9	-42.9	0	0	0	0	110.4
448	F	30.1	Very low	29.4	Very low	183 Å²	183	148.9 Å²	148.9	80%	0.803	81%	0.808	S	S	*	*			trans	90.8	126.8	174.6	-60.2	-76	0	0	0	115
449	T	28.6	Very low	29	Very low	114 Å²	114	147.6 Å²	147.6	70%	0.699	81%	0.808	S	S	*	*			cis	-165.7	145.2	9.4	13.1	0	0	0	0	110.5
450	N	31.2	Very low	28.9	Very low	144 Å²	144	148 Å²	148	77%	0.77	82%	0.815	S	S	*	*			trans	51.7	154.4	148.5	-82.1	-35.6	0	0	0	122
451	L	30.8	Very low	29.4	Very low	133 Å²	133	143.6 Å²	143.6	70%	0.696	81%	0.807	S	S	*	*			cis	174.6	138.3	-32.2	-168	81.9	0	0	0	102.8
452	D	27.9	Very low	30.4	Very low	144 Å²	144	139.9 Å²	139.9	77%	0.77	80%	0.799	S	S	*	*			trans	60.3	97.8	165	-64.7	-24.8	0	0	0	119.6
453	A	29.3	Very low	30.4	Very low	91 Å²	91	140.3 Å²	140.3	75%	0.752	80%	0.8	S	S	*	*			trans	-159.4	95.6	138.5	0	0	0	0	0	112.8
454	F	28.5	Very low	30.8	Very low	207 Å²	207	140.2 Å²	140.2	91%	0.908	80%	0.797	S	S	*	*			trans	69.3	114.4	143.4	-72.2	-85	0	0	0	122.8
455	H	31.7	Very low	30.9	Very low	178 Å²	178	143.4 Å²	143.4	82%	0.824	80%	0.802	S	S	*	*			trans	-62.3	140	154.3	-73.8	-93.2	0	0	0	112.6
456	T	29	Very low	31.4	Very low	145 Å²	145	144.7 Å²	144.7	89%	0.89	81%	0.808	S	S	*	*				157.1	132.7	124.7	42.9	0	0	0	0	112.4
457	L	28.2	Very low	31.6	Very low	169 Å²	169	142.7 Å²	142.7	89%	0.885	80%	0.803	S	S	*	*			trans	-77.8	-175.7	-174.6	-72.9	160.3	0	0	0	113.4
458	P	40.1	Very low	32.2	Very low	119 Å²	119	142.6 Å²	142.6	77%	0.773	81%	0.806	S	S	*	*			cis	-137	-173.9	-33.2	30.9	-8.7	0	0	0	114.5
459	A	25.9	Very low	32.7	Very low	105 Å²	105	137.9 Å²	137.9	87%	0.868	79%	0.794	S	S	*	*			trans	108.6	125	157.4	0	0	0	0	0	119.1
460	C	24.8	Very low	33.2	Very low	125 Å²	125	135 Å²	135	85%	0.845	78%	0.778	S	S	*	*			trans	-91.1	-175	-178.8	-72.9	0	0	0	0	112.8
461	P	40.3	Very low	34.1	Very low	116 Å²	116	132.6 Å²	132.6	75%	0.753	77%	0.771	S	S	*	*				-132.6	-151.9	-50.4	41.2	-22.5	0	0	0	109.9
462	P	47.1	Very low	34.7	Very low	107 Å²	107	129 Å²	129	70%	0.695	76%	0.76	S	S	*	*			cis	-128.2	159.6	-20.2	36.3	-18.8	0	0	0	114.7
463	T	28	Very low	35.2	Very low	135 Å²	135	126.1 Å²	126.1	83%	0.828	75%	0.745	S	S	*	*			trans	-167.1	149.2	144.1	7.2	0	0	0	0	109.7
464	P	37.7	Very low	35.7	Very low	123 Å²	123	127.6 Å²	127.6	80%	0.799	74%	0.736	S	S	*	*			trans	-81	135.2	-155.2	33	-33	0	0	0	111.4
465	R	28	Very low	36.4	Very low	244 Å²	244	127.4 Å²	127.4	92%	0.921	73%	0.729	S	S	*	*			trans	-132.4	131.5	166.3	-78.8	-168.3	175.8	-173.2	0.1	111.3
466	L	35.3	Very low	36.8	Very low	170 Å²	170	124.7 Å²	124.7	89%	0.89	72%	0.717	S	S	*	*			trans	-15.4	117.9	168.2	-138	72.7	0	0	0	114.4	S468	L466-S468 PolarHBondContact O-N 3.24Å
467	V	34.7	Very low	37.4	Very low	138 Å²	138	119.9 Å²	119.9	84%	0.836	69%	0.692	S	S	*	*			trans	-65.3	112.9	169.7	174.1	0	0	0	0	108.5
468	S	39.9	Very low	38.4	Very low	104 Å²	104	116.6 Å²	116.6	73%	0.727	68%	0.679	S	S	*	*	P	Polyproline II helix	trans	-71.3	133.6	162.9	-43.8	0	0	0	0	108.6	L466	L466-S468 PolarHBondContact O-N 3.24Å
469	P	39.4	Very low	38.6	Very low	84 Å²	84	113.5 Å²	113.5	55%	0.545	66%	0.663	S	S	.	*	P	Polyproline II helix	trans	-65.6	143.9	-178.5	-14.4	27.5	0	0	0	111.6	D473	P469-D473 HydrophobicContact CB-CB 4.25Å
470	S	38.7	Very low	39.5	Very low	53 Å²	53	114.1 Å²	114.1	37%	0.371	65%	0.65	S	S	.	*	P	Polyproline II helix	trans	-61.3	148.3	176.1	165.9	0	0	0	0	111.3	A472 D473 Q474	S470-A472 PolarHBondContact O-N 3.06Å; S470-A472 VanDerWaalsContact O-N 3.12Å; S470-A472 WeakPolarHBondContact OG-CB 3.46Å; S470-A472 PolarHBondContact OG-N 3.48Å; S470-A472 VanDerWaalsContact OG-N 3.13Å; S470-D473 WeakPolarHBondContact CB-OD2 3.38Å; S470-D473 PolarHBondContact N-OD2 3.08Å; S470-D473 WeakPolarHBondContact O-CB 3.49Å; S470-D473 PolarHBondContact O-N 3.34Å; S470-Q474 PolarHBondContact O-N 3.49Å; S470-Q474 VanDerWaalsContact O-N 3.09Å
471	P	50.3	Low	40.8	Very low	94 Å²	94	112.4 Å²	112.4	61%	0.61	63%	0.632	S	S	*	*	H	α-helix	trans	-60.4	-17.6	171	22.6	-31.1	0	0	0	113.3	R475	P471-R475 WeakPolarHBondContact O-CG 3.45Å; P471-R475 PolarHBondContact O-N 3.33Å
472	A	43.4	Very low	41.3	Very low	57 Å²	57	110 Å²	110	47%	0.471	62%	0.618	S	S	.	*	H	α-helix	trans	-71.6	-43.2	168.7	0	0	0	0	0	111.8	S470 Q474 R475 E476	S470-A472 PolarHBondContact O-N 3.06Å; S470-A472 VanDerWaalsContact O-N 3.12Å; S470-A472 WeakPolarHBondContact OG-CB 3.46Å; S470-A472 PolarHBondContact OG-N 3.48Å; S470-A472 VanDerWaalsContact OG-N 3.13Å; A472-Q474 VanDerWaalsContact C-N 3.31Å; A472-Q474 PolarHBondContact O-N 2.79Å; A472-R475 PolarHBondContact O-N 2.92Å; A472-R475 VanDerWaalsContact O-N 3.16Å; A472-E476 PolarHBondContact O-N 3.02Å
473	D	38.5	Very low	41.5	Very low	84 Å²	84	106.3 Å²	106.3	45%	0.449	60%	0.597	S	S	.	*	H	α-helix	trans	-65.6	-33.6	176.2	-63.2	-36	0	0	0	111.7	P469 S470 A477	P469-D473 HydrophobicContact CB-CB 4.25Å; S470-D473 WeakPolarHBondContact CB-OD2 3.38Å; S470-D473 PolarHBondContact N-OD2 3.08Å; S470-D473 WeakPolarHBondContact O-CB 3.49Å; S470-D473 PolarHBondContact O-N 3.34Å; D473-A477 WeakPolarHBondContact O-CB 3.48Å; D473-A477 PolarHBondContact O-N 3Å
474	Q	41	Very low	42.8	Very low	122 Å²	122	103.3 Å²	103.3	57%	0.57	58%	0.579	S	S	*	*	H	α-helix	trans	-69.3	-36.1	173.4	-78.7	-175.8	-11.2	0	0	112.6	S470 A472 V478	S470-Q474 PolarHBondContact O-N 3.49Å; S470-Q474 VanDerWaalsContact O-N 3.09Å; A472-Q474 VanDerWaalsContact C-N 3.31Å; A472-Q474 PolarHBondContact O-N 2.79Å; Q474-V478 VanDerWaalsContact O-CB 3.3Å; Q474-V478 WeakPolarHBondContact O-CB 3.3Å; Q474-V478 WeakPolarHBondContact O-CG2 3.18Å; Q474-V478 PolarHBondContact O-N 3.09Å
475	R	43	Very low	43.8	Very low	203 Å²	203	105.3 Å²	105.3	77%	0.766	57%	0.571	S	S	*	*	H	α-helix	trans	-70.6	-40.5	175.6	-77.3	177.6	178.6	-179.1	0.6	111.5	P471 A472 A479	P471-R475 WeakPolarHBondContact O-CG 3.45Å; P471-R475 PolarHBondContact O-N 3.33Å; A472-R475 PolarHBondContact O-N 2.92Å; A472-R475 VanDerWaalsContact O-N 3.16Å; R475-A479 VanDerWaalsContact O-CB 3.26Å; R475-A479 WeakPolarHBondContact O-CB 3.26Å; R475-A479 PolarHBondContact O-N 2.91Å
476	E	40.3	Very low	45.4	Very low	122 Å²	122	95.6 Å²	95.6	57%	0.57	54%	0.54	S	S	*	.	H	α-helix	trans	-66.9	-43.1	172.4	-84.7	-177.2	157.9	0	0	111.8	A472 V478 A479 I480	A472-E476 PolarHBondContact O-N 3.02Å; E476-V478 PolarHBondContact O-N 3.48Å; E476-A479 PolarHBondContact O-N 3.47Å; E476-I480 HydrophobicContact CB-CD1 4.32Å; E476-I480 VanDerWaalsContact O-CB 3.28Å; E476-I480 WeakPolarHBondContact O-CB 3.21Å; E476-I480 WeakPolarHBondContact O-CD1 3.45Å; E476-I480 WeakPolarHBondContact O-CG1 3.3Å; E476-I480 PolarHBondContact O-N 2.93Å
477	A	40.2	Very low	47.1	Very low	43 Å²	43	92.4 Å²	92.4	36%	0.355	52%	0.521	S	S	.	.	H	α-helix	trans	-63.4	-40.3	176.1	0	0	0	0	0	112.3	D473 I481	D473-A477 WeakPolarHBondContact O-CB 3.48Å; D473-A477 PolarHBondContact O-N 3Å; A477-I481 VanDerWaalsContact O-CB 3.31Å; A477-I481 WeakPolarHBondContact O-CB 3.46Å; A477-I481 WeakPolarHBondContact O-CD1 3.5Å; A477-I481 WeakPolarHBondContact O-CG1 3.47Å; A477-I481 PolarHBondContact O-N 3.27Å
478	V	49.6	Very low	49	Very low	100 Å²	100	92.7 Å²	92.7	61%	0.606	51%	0.507	S	S	*	.	H	α-helix	trans	-68.3	-37.1	174.9	171.4	0	0	0	0	111.4	Q474 E476 S482	Q474-V478 VanDerWaalsContact O-CB 3.3Å; Q474-V478 WeakPolarHBondContact O-CB 3.3Å; Q474-V478 WeakPolarHBondContact O-CG2 3.18Å; Q474-V478 PolarHBondContact O-N 3.09Å; E476-V478 PolarHBondContact O-N 3.48Å; V478-S482 WeakPolarHBondContact O-CB 3.3Å; V478-S482 PolarHBondContact O-N 3.09Å; V478-S482 PolarHBondContact O-OG 2.96Å
479	A	44	Very low	50.8	Low	54 Å²	54	91 Å²	91	45%	0.446	49%	0.485	S	S	.	.	H	α-helix	trans	-66.7	-44.8	174.1	0	0	0	0	0	112.1	R475 E476 I481 S482 A483	R475-A479 VanDerWaalsContact O-CB 3.26Å; R475-A479 WeakPolarHBondContact O-CB 3.26Å; R475-A479 PolarHBondContact O-N 2.91Å; E476-A479 PolarHBondContact O-N 3.47Å; A479-I481 PolarHBondContact O-N 3.29Å; A479-S482 WeakPolarHBondContact CA-OG 3.04Å; A479-S482 PolarHBondContact O-N 3.46Å; A479-S482 PolarHBondContact O-OG 3.27Å; A479-S482 VanDerWaalsContact O-OG 3.08Å; A479-A483 WeakPolarHBondContact O-CB 3.45Å; A479-A483 PolarHBondContact O-N 3.03Å
480	I	46.6	Very low	52.6	Low	118 Å²	118	90.9 Å²	90.9	61%	0.605	47%	0.473	S	S	*	.	H	α-helix	trans	-69.9	-29.4	-179.8	-66	163.8	0	0	0	111.8	E476 P484	E476-I480 HydrophobicContact CB-CD1 4.32Å; E476-I480 VanDerWaalsContact O-CB 3.28Å; E476-I480 WeakPolarHBondContact O-CB 3.21Å; E476-I480 WeakPolarHBondContact O-CD1 3.45Å; E476-I480 WeakPolarHBondContact O-CG1 3.3Å; E476-I480 PolarHBondContact O-N 2.93Å; I480-P484 WeakPolarHBondContact O-CD 3.27Å; I480-P484 VanDerWaalsContact O-CG 3.22Å; I480-P484 WeakPolarHBondContact O-CG 3.44Å
481	I	51.2	Low	54.6	Low	90 Å²	90	92.4 Å²	92.4	46%	0.462	47%	0.471	S	S	.	.	H	α-helix	trans	-84.4	-30	175.5	-65.3	165.3	0	0	0	112	A477 A479	A477-I481 VanDerWaalsContact O-CB 3.31Å; A477-I481 WeakPolarHBondContact O-CB 3.46Å; A477-I481 WeakPolarHBondContact O-CD1 3.5Å; A477-I481 WeakPolarHBondContact O-CG1 3.47Å; A477-I481 PolarHBondContact O-N 3.27Å; A479-I481 PolarHBondContact O-N 3.29Å
482	S	51	Low	56.2	Low	65 Å²	65	89.2 Å²	89.2	46%	0.455	45%	0.451	S	S	.	.	H	α-helix	trans	-78.9	-34.6	-180	58.6	0	0	0	0	113.4	V478 A479 S486	V478-S482 WeakPolarHBondContact O-CB 3.3Å; V478-S482 PolarHBondContact O-N 3.09Å; V478-S482 PolarHBondContact O-OG 2.96Å; A479-S482 WeakPolarHBondContact CA-OG 3.04Å; A479-S482 PolarHBondContact O-N 3.46Å; A479-S482 PolarHBondContact O-OG 3.27Å; A479-S482 VanDerWaalsContact O-OG 3.08Å; S482-S486 WeakPolarHBondContact O-CB 3.39Å; S482-S486 PolarHBondContact O-N 3.18Å
483	A	50.4	Low	58.1	Low	30 Å²	30	86.5 Å²	86.5	25%	0.248	43%	0.428	C	S	.	.	H	α-helix	trans	-57.8	-54.3	177	0	0	0	0	0	114.4	A479 R485 S486 Q487	A479-A483 WeakPolarHBondContact O-CB 3.45Å; A479-A483 PolarHBondContact O-N 3.03Å; A483-R485 PolarHBondContact O-N 3.35Å; A483-S486 PolarHBondContact O-N 3.05Å; A483-S486 PolarHBondContact O-OG 3.06Å; A483-Q487 PolarHBondContact O-N 2.9Å; A483-Q487 VanDerWaalsContact O-N 3.17Å
484	P	56.1	Low	60.4	Low	71 Å²	71	83.8 Å²	83.8	46%	0.461	41%	0.412	S	S	.	.	H	α-helix	trans	-68.6	-32.5	-178.8	24.3	-32.1	0	0	0	113	I480 Q487 W488	I480-P484 WeakPolarHBondContact O-CD 3.27Å; I480-P484 VanDerWaalsContact O-CG 3.22Å; I480-P484 WeakPolarHBondContact O-CG 3.44Å; P484-Q487 PolarHBondContact O-N 3.4Å; P484-W488 PolarHBondContact O-N 3.47Å; P484-W488 VanDerWaalsContact O-N 3.1Å
485	R	58.6	Low	62.6	Low	166 Å²	166	78.5 Å²	78.5	63%	0.626	39%	0.388	S	S	*	.	H	α-helix	trans	-66.9	-37.1	174.2	-76.1	-178.4	175.9	174.6	0.9	112.1	A483 R489	A483-R485 PolarHBondContact O-N 3.35Å; R485-R489 VanDerWaalsContact O-CG 3.31Å; R485-R489 WeakPolarHBondContact O-CG 3.35Å; R485-R489 PolarHBondContact O-N 2.88Å
486	S	62.3	Low	64.9	Low	39 Å²	39	69.7 Å²	69.7	27%	0.273	36%	0.355	S	S	.	.	H	α-helix	trans	-68.6	-37.8	176.7	83.8	0	0	0	0	112	S482 A483 R490	S482-S486 WeakPolarHBondContact O-CB 3.39Å; S482-S486 PolarHBondContact O-N 3.18Å; A483-S486 PolarHBondContact O-N 3.05Å; A483-S486 PolarHBondContact O-OG 3.06Å; S486-R490 WeakPolarHBondContact O-CG 3.11Å; S486-R490 PolarHBondContact O-N 2.93Å
487	Q	69.8	Low	67.3	Low	104 Å²	104	63.9 Å²	63.9	49%	0.486	33%	0.328	S	S	.	.	H	α-helix	trans	-66.9	-48.4	177.8	-71.5	175.7	-2.8	0	0	111.5	A483 P484 R489 R490 R491	A483-Q487 PolarHBondContact O-N 2.9Å; A483-Q487 VanDerWaalsContact O-N 3.17Å; P484-Q487 PolarHBondContact O-N 3.4Å; Q487-R489 VanDerWaalsContact C-N 3.31Å; Q487-R489 PolarHBondContact O-N 3.27Å; Q487-R490 PolarHBondContact O-N 2.86Å; Q487-R491 WeakPolarHBondContact O-CG 3.35Å; Q487-R491 PolarHBondContact O-N 3.34Å
488	W	75.7	Confident	69.7	Low	144 Å²	144	62.9 Å²	62.9	55%	0.545	32%	0.317	S	S	.	.	H	α-helix	trans	-57.7	-41.8	178.2	176.2	85.8	0	0	0	112.7	F289 P484 R491 C492	F289-W488 AromaticContact CE2-CD1 4Å; F289-W488 AromaticContact CZ-CD1 3.54Å; F289-W488 HydrophobicContact CZ-CG 4.48Å; F289-W488 AromaticContact CZ-NE1 3.97Å; P484-W488 PolarHBondContact O-N 3.47Å; P484-W488 VanDerWaalsContact O-N 3.1Å; W488-R491 PolarHBondContact O-N 3.29Å; W488-C492 WeakPolarHBondContact O-CB 3.18Å; W488-C492 PolarHBondContact O-N 3.48Å
489	R	77.4	Confident	71.9	Confident	68 Å²	68	58.4 Å²	58.4	26%	0.257	29%	0.289	S	S	.	.	H	α-helix	trans	-62.4	-44.2	177.1	-72	174.9	179.3	-166.8	-5.8	112.2	I349 F352 D353 R485 Q487 C492 L493	I349-R489 HydrophobicContact CG2-CB 4.49Å; I349-R489 HydrophobicContact CG2-CG 4.37Å; F352-R489 PolarHBondContact O-NH1 3.4Å; D353-R489 IonicContact OD1-NH1 3.83Å; R485-R489 VanDerWaalsContact O-CG 3.31Å; R485-R489 WeakPolarHBondContact O-CG 3.35Å; R485-R489 PolarHBondContact O-N 2.88Å; Q487-R489 VanDerWaalsContact C-N 3.31Å; Q487-R489 PolarHBondContact O-N 3.27Å; R489-C492 PolarHBondContact O-N 2.95Å; R489-L493 WeakPolarHBondContact O-CB 3.16Å; R489-L493 VanDerWaalsContact O-CG 3.27Å; R489-L493 WeakPolarHBondContact O-CG 2.93Å; R489-L493 PolarHBondContact O-N 3.38Å
490	R	77.2	Confident	74.3	Confident	82 Å²	82	55.9 Å²	55.9	31%	0.309	27%	0.268	S	S	.	.	H	α-helix	trans	-62.2	-45	177.2	-71.7	-178.4	-165.5	-154.5	12.7	112.1	S486 Q487 C492 L493 R494 S562	S486-R490 WeakPolarHBondContact O-CG 3.11Å; S486-R490 PolarHBondContact O-N 2.93Å; Q487-R490 PolarHBondContact O-N 2.86Å; R490-C492 VanDerWaalsContact C-N 3.35Å; R490-C492 PolarHBondContact O-N 2.95Å; R490-L493 PolarHBondContact O-N 2.7Å; R490-R494 PolarHBondContact O-N 2.94Å; R490-S562 WeakPolarHBondContact CD-O 3.47Å; R490-S562 WeakPolarHBondContact CG-O 3.47Å
491	R	80.3	Confident	76.5	Confident	84 Å²	84	51.4 Å²	51.4	32%	0.317	25%	0.245	S	C	.	.	H	α-helix	trans	-60.7	-44.3	176.3	-61.9	-167.3	-176.6	160.5	1.9	111.7	E287 F289 Q487 W488 L493 R494 D495	E287-R491 HydrophobicContact CB-CG 4.2Å; E287-R491 VanDerWaalsContact O-CB 3.3Å; E287-R491 WeakPolarHBondContact O-CB 3.44Å; E287-R491 WeakPolarHBondContact O-CD 3.42Å; E287-R491 WeakPolarHBondContact O-CG 3.2Å; F289-R491 HydrophobicContact CD2-CB 3.7Å; F289-R491 HydrophobicContact CE2-CB 3.28Å; F289-R491 HydrophobicContact CE2-CG 4.35Å; F289-R491 HydrophobicContact CZ-CB 4.02Å; Q487-R491 WeakPolarHBondContact O-CG 3.35Å; Q487-R491 PolarHBondContact O-N 3.34Å; W488-R491 PolarHBondContact O-N 3.29Å; R491-L493 PolarHBondContact O-N 2.87Å; R491-R494 PolarHBondContact O-N 3.32Å; R491-D495 PolarHBondContact O-N 3.3Å
492	C	84.1	Confident	78.6	Confident	28 Å²	28	49.2 Å²	49.2	19%	0.189	23%	0.234	C	C	.	.	H	α-helix	trans	-61.6	-42.8	175.8	-175.3	0	0	0	0	112.3	W488 R489 R490 D495 I496	W488-C492 WeakPolarHBondContact O-CB 3.18Å; W488-C492 PolarHBondContact O-N 3.48Å; R489-C492 PolarHBondContact O-N 2.95Å; R490-C492 VanDerWaalsContact C-N 3.35Å; R490-C492 PolarHBondContact O-N 2.95Å; C492-D495 PolarHBondContact O-N 3.36Å; C492-I496 WeakPolarHBondContact O-CB 3.13Å; C492-I496 VanDerWaalsContact O-CG1 3.27Å; C492-I496 WeakPolarHBondContact O-CG1 3.46Å; C492-I496 PolarHBondContact O-N 3.48Å
493	L	84	Confident	80.7	Confident	0 Å²	0	46.1 Å²	46.1	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-65.2	-38	177	-72.4	168.6	0	0	0	112.7	I349 Y350 F420 R489 R490 R491 I496 A497	I349-L493 HydrophobicContact CG2-CD2 4.25Å; I349-L493 HydrophobicContact CG2-CG 4.33Å; Y350-L493 HydrophobicContact CD1-CD1 3.9Å; Y350-L493 HydrophobicContact CD1-CD2 4.19Å; Y350-L493 HydrophobicContact CD2-CD2 4.04Å; Y350-L493 HydrophobicContact CE1-CD1 3.29Å; Y350-L493 HydrophobicContact CE1-CD2 3.81Å; Y350-L493 HydrophobicContact CE1-CG 4.16Å; Y350-L493 HydrophobicContact CE2-CD2 3.57Å; Y350-L493 HydrophobicContact CG-CD2 4.32Å; Y350-L493 VanDerWaalsContact CZ-CD2 3.46Å; F420-L493 HydrophobicContact CE2-CD2 4.29Å; R489-L493 WeakPolarHBondContact O-CB 3.16Å; R489-L493 VanDerWaalsContact O-CG 3.27Å; R489-L493 WeakPolarHBondContact O-CG 2.93Å; R489-L493 PolarHBondContact O-N 3.38Å; R490-L493 PolarHBondContact O-N 2.7Å; R491-L493 PolarHBondContact O-N 2.87Å; L493-I496 PolarHBondContact O-N 2.94Å; L493-A497 WeakPolarHBondContact O-CB 3.41Å; L493-A497 PolarHBondContact O-N 3.41Å
494	R	84.9	Confident	82.9	Confident	26 Å²	26	44.7 Å²	44.7	10%	0.098	20%	0.201	C	C	.	.	H	α-helix	trans	-62	-45.3	172.8	-76.8	-172.9	-177.1	157.3	10	111.9	E287 R490 R491 A497 L498 Y559 S562	E287-R494 IonicContact OE2-CZ 3.82Å; E287-R494 IonicContact OE2-NH1 2.74Å; E287-R494 PolarHBondContact OE2-NH1 3.04Å; E287-R494 IonicContact OE2-NH2 2.8Å; R490-R494 PolarHBondContact O-N 2.94Å; R491-R494 PolarHBondContact O-N 3.32Å; R494-A497 PolarHBondContact O-N 2.84Å; R494-L498 WeakPolarHBondContact O-CG 3.28Å; R494-L498 PolarHBondContact O-N 2.94Å; R494-Y559 HydrophobicContact CB-CD2 3.83Å; R494-Y559 HydrophobicContact CB-CE2 3.83Å; R494-Y559 HydrophobicContact CG-CD2 3.89Å; R494-Y559 HydrophobicContact CG-CE2 3.98Å; R494-S562 PolarHBondContact NE-OXT 3.31Å; R494-S562 PolarHBondContact NH2-OXT 3.21Å
495	D	88.8	Confident	84.6	Confident	12 Å²	12	43 Å²	43	6%	0.064	19%	0.189	C	C	.	.	H	α-helix	trans	-60.7	-44.6	175.3	-88.7	58.1	0	0	0	112	T288 F289 F290 A291 G292 R491 C492 L498 F499	T288-D495 WeakPolarHBondContact CA-OD1 3.29Å; T288-D495 WeakPolarHBondContact CG2-OD1 3.39Å; F289-D495 WeakPolarHBondContact CB-OD2 3.02Å; F289-D495 PolarHBondContact N-OD1 3.43Å; F290-D495 PolarHBondContact N-OD2 2.81Å; A291-D495 PolarHBondContact N-OD2 3.36Å; G292-D495 PolarHBondContact N-OD2 3.22Å; R491-D495 PolarHBondContact O-N 3.3Å; C492-D495 PolarHBondContact O-N 3.36Å; D495-L498 PolarHBondContact O-N 3.49Å; D495-F499 WeakPolarHBondContact O-CB 3.47Å; D495-F499 PolarHBondContact O-N 2.9Å
496	I	91.1	Very high	86.4	Confident	17 Å²	17	35.1 Å²	35.1	9%	0.087	16%	0.159	C	C	.	.	H	α-helix	trans	-59.6	-48.1	175.9	-73.2	172	0	0	0	110.7	V342 I349 F420 C492 L493 L498 F499 L500	V342-I496 HydrophobicContact CG1-CB 4.17Å; V342-I496 HydrophobicContact CG1-CG1 4Å; V342-I496 HydrophobicContact CG1-CG2 3.66Å; I349-I496 HydrophobicContact CD1-CD1 3.95Å; F420-I496 HydrophobicContact CE1-CG2 4.2Å; F420-I496 HydrophobicContact CE2-CG2 4.11Å; F420-I496 HydrophobicContact CZ-CG2 3.63Å; C492-I496 WeakPolarHBondContact O-CB 3.13Å; C492-I496 VanDerWaalsContact O-CG1 3.27Å; C492-I496 WeakPolarHBondContact O-CG1 3.46Å; C492-I496 PolarHBondContact O-N 3.48Å; L493-I496 PolarHBondContact O-N 2.94Å; I496-L498 PolarHBondContact O-N 2.86Å; I496-F499 PolarHBondContact O-N 2.93Å; I496-L500 HydrophobicContact CG2-CD1 3.86Å; I496-L500 HydrophobicContact CG2-CG 4.4Å; I496-L500 WeakPolarHBondContact O-CB 3.4Å; I496-L500 VanDerWaalsContact O-CG 3.3Å; I496-L500 WeakPolarHBondContact O-CG 3.49Å; I496-L500 PolarHBondContact O-N 3.47Å
497	A	90.3	Very high	87.9	Confident	0 Å²	0	33.7 Å²	33.7	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-61.4	-44.6	-179	0	0	0	0	0	111.8	L493 R494 L500 L501 V558	L493-A497 WeakPolarHBondContact O-CB 3.41Å; L493-A497 PolarHBondContact O-N 3.41Å; R494-A497 PolarHBondContact O-N 2.84Å; A497-L500 PolarHBondContact O-N 3.29Å; A497-L501 VanDerWaalsContact O-CB 3.22Å; A497-L501 WeakPolarHBondContact O-CB 3.4Å; A497-L501 PolarHBondContact O-N 3.47Å; A497-V558 HydrophobicContact CB-CG1 4.38Å
498	L	90.7	Very high	89	Confident	23 Å²	23	30.1 Å²	30.1	12%	0.12	13%	0.131	C	C	.	.	H	α-helix	trans	-68.2	-39.9	178	-70.7	177.9	0	0	0	113	T288 P293 R494 D495 I496 L501 L502 Y559	T288-L498 HydrophobicContact CG2-CD1 3.97Å; P293-L498 HydrophobicContact CG-CB 3.9Å; P293-L498 HydrophobicContact CG-CD1 3.59Å; P293-L498 HydrophobicContact CG-CG 4.42Å; R494-L498 WeakPolarHBondContact O-CG 3.28Å; R494-L498 PolarHBondContact O-N 2.94Å; D495-L498 PolarHBondContact O-N 3.49Å; I496-L498 PolarHBondContact O-N 2.86Å; L498-L501 PolarHBondContact O-N 2.92Å; L498-L502 PolarHBondContact O-N 3.27Å; L498-L502 VanDerWaalsContact O-N 3.09Å; L498-Y559 HydrophobicContact CD1-CD2 3.93Å; L498-Y559 HydrophobicContact CD1-CE2 3.41Å; L498-Y559 VanDerWaalsContact CD1-CE2 3.41Å; L498-Y559 HydrophobicContact CD2-CD1 4.29Å; L498-Y559 HydrophobicContact CD2-CD2 3.86Å; L498-Y559 HydrophobicContact CD2-CE1 4.4Å; L498-Y559 HydrophobicContact CD2-CE2 3.99Å; L498-Y559 HydrophobicContact CD2-CG 4.01Å; L498-Y559 HydrophobicContact CG-CD2 3.57Å; L498-Y559 HydrophobicContact CG-CE2 3.62Å; L498-Y559 HydrophobicContact CG-CG 4.22Å
499	F	94.8	Very high	89.6	Confident	6 Å²	6	24.5 Å²	24.5	3%	0.026	11%	0.111	C	C	.	.	H	α-helix	trans	-58.7	-52.3	173.3	169	-97.8	0	0	0	111.1	L295 L299 L338 T339 V342 D495 I496 L501 L502 C503	L295-F499 HydrophobicContact CB-CD2 4.19Å; L295-F499 HydrophobicContact CB-CE2 4.33Å; L295-F499 HydrophobicContact CD2-CD2 4.1Å; L295-F499 HydrophobicContact CD2-CE2 3.7Å; L295-F499 HydrophobicContact CD2-CZ 4.44Å; L295-F499 HydrophobicContact CG-CD2 4.13Å; L295-F499 HydrophobicContact CG-CE2 3.77Å; L299-F499 HydrophobicContact CD1-CE2 3.79Å; L299-F499 HydrophobicContact CD1-CZ 3.98Å; L338-F499 HydrophobicContact CB-CZ 4.12Å; T339-F499 HydrophobicContact CG2-CE1 4.07Å; T339-F499 HydrophobicContact CG2-CZ 4.45Å; V342-F499 HydrophobicContact CB-CD1 4.05Å; V342-F499 HydrophobicContact CB-CE1 3.94Å; V342-F499 HydrophobicContact CG1-CD1 3.73Å; V342-F499 HydrophobicContact CG1-CE1 4.16Å; V342-F499 HydrophobicContact CG2-CD1 3.95Å; V342-F499 HydrophobicContact CG2-CE1 3.69Å; V342-F499 HydrophobicContact CG2-CZ 4.46Å; D495-F499 WeakPolarHBondContact O-CB 3.47Å; D495-F499 PolarHBondContact O-N 2.9Å; I496-F499 PolarHBondContact O-N 2.93Å; F499-L501 VanDerWaalsContact C-N 3.26Å; F499-L501 PolarHBondContact O-N 3.11Å; F499-L502 PolarHBondContact O-N 3.07Å; F499-C503 PolarHBondContact O-N 3.2Å; F499-C503 VanDerWaalsContact O-N 3.11Å; F499-C503 PolarHBondContact O-SG 3.19Å; F499-C503 VanDerWaalsContact O-SG 3.34Å
500	L	95.1	Very high	90.3	Very high	0 Å²	0	21.3 Å²	21.3	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-62.4	-36.6	179.7	-68.7	176.3	0	0	0	111.3	T339 V342 F420 I496 A497 C503 N504 L555	T339-L500 HydrophobicContact CG2-CD2 4.05Å; V342-L500 HydrophobicContact CB-CD2 4.3Å; V342-L500 HydrophobicContact CG1-CD1 4.37Å; V342-L500 HydrophobicContact CG1-CD2 4.03Å; V342-L500 HydrophobicContact CG1-CG 4.02Å; F420-L500 HydrophobicContact CD1-CD1 3.85Å; F420-L500 HydrophobicContact CE1-CD1 3.71Å; F420-L500 HydrophobicContact CZ-CD1 4.47Å; I496-L500 HydrophobicContact CG2-CD1 3.86Å; I496-L500 HydrophobicContact CG2-CG 4.4Å; I496-L500 WeakPolarHBondContact O-CB 3.4Å; I496-L500 VanDerWaalsContact O-CG 3.3Å; I496-L500 WeakPolarHBondContact O-CG 3.49Å; I496-L500 PolarHBondContact O-N 3.47Å; A497-L500 PolarHBondContact O-N 3.29Å; L500-C503 PolarHBondContact O-N 3.08Å; L500-N504 PolarHBondContact O-N 2.99Å; L500-N504 PolarHBondContact O-ND2 3.44Å; L500-L555 HydrophobicContact CB-CD1 3.59Å; L500-L555 HydrophobicContact CB-CD2 4.04Å; L500-L555 HydrophobicContact CB-CG 4.45Å; L500-L555 HydrophobicContact CD1-CD2 4.02Å
501	L	93.9	Very high	90.8	Very high	25 Å²	25	18.2 Å²	18.2	13%	0.131	9%	0.09	C	C	.	.	H	α-helix	trans	-59.6	-54	177.2	-175.3	156	0	0	0	110.5	A497 L498 F499 C503 N504 V505 V552 L555 L556	A497-L501 VanDerWaalsContact O-CB 3.22Å; A497-L501 WeakPolarHBondContact O-CB 3.4Å; A497-L501 PolarHBondContact O-N 3.47Å; L498-L501 PolarHBondContact O-N 2.92Å; F499-L501 VanDerWaalsContact C-N 3.26Å; F499-L501 PolarHBondContact O-N 3.11Å; L501-C503 VanDerWaalsContact C-N 3.34Å; L501-C503 PolarHBondContact O-N 2.84Å; L501-N504 PolarHBondContact O-N 3.27Å; L501-N504 VanDerWaalsContact O-N 3.17Å; L501-V505 HydrophobicContact CD2-CG2 4.17Å; L501-V505 WeakPolarHBondContact O-CG2 3.3Å; L501-V505 PolarHBondContact O-N 2.73Å; L501-V552 HydrophobicContact CG-CG1 4.16Å; L501-L555 HydrophobicContact CB-CB 4.38Å; L501-L556 HydrophobicContact CD1-CB 3.9Å; L501-L556 HydrophobicContact CD1-CD1 4.09Å
502	L	94	Very high	90.9	Very high	44 Å²	44	14.4 Å²	14.4	23%	0.23	8%	0.076	C	C	.	.	H	α-helix	trans	-61.5	-41	-179.2	-69.3	171.8	0	0	0	112.3	P293 L297 L498 F499 V505 I506	P293-L502 WeakPolarHBondContact O-CD1 3.46Å; L297-L502 HydrophobicContact CB-CD1 4.43Å; L498-L502 PolarHBondContact O-N 3.27Å; L498-L502 VanDerWaalsContact O-N 3.09Å; F499-L502 PolarHBondContact O-N 3.07Å; L502-V505 PolarHBondContact O-N 2.96Å; L502-I506 PolarHBondContact O-N 3.05Å
503	C	95.7	Very high	90.7	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-63.3	-40	175.4	-67.5	0	0	0	0	112.5	T339 F499 L500 L501 V505 I506 L507	T339-C503 HydrophobicContact CG2-CB 3.48Å; T339-C503 VanDerWaalsContact CG2-CB 3.48Å; F499-C503 PolarHBondContact O-N 3.2Å; F499-C503 VanDerWaalsContact O-N 3.11Å; F499-C503 PolarHBondContact O-SG 3.19Å; F499-C503 VanDerWaalsContact O-SG 3.34Å; L500-C503 PolarHBondContact O-N 3.08Å; L501-C503 VanDerWaalsContact C-N 3.34Å; L501-C503 PolarHBondContact O-N 2.84Å; C503-V505 VanDerWaalsContact C-N 3.34Å; C503-I506 WeakPolarHBondContact O-CG2 3.49Å; C503-I506 PolarHBondContact O-N 3.31Å; C503-L507 WeakPolarHBondContact O-CB 3.32Å; C503-L507 VanDerWaalsContact O-CG 3.26Å; C503-L507 WeakPolarHBondContact O-CG 3.43Å; C503-L507 PolarHBondContact O-N 3.48Å; C503-L507 VanDerWaalsContact O-N 3.08Å
504	N	95.4	Very high	90.2	Very high	0 Å²	0	18.1 Å²	18.1	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-69.9	-31.6	176.5	-81.2	-92.1	0	0	0	112.4	Q417 L500 L501 W508 R548 V552	Q417-N504 PolarHBondContact NE2-ND2 3.12Å; Q417-N504 PolarHBondContact NE2-OD1 2.77Å; Q417-N504 PolarHBondContact OE1-OD1 3.17Å; L500-N504 PolarHBondContact O-N 2.99Å; L500-N504 PolarHBondContact O-ND2 3.44Å; L501-N504 PolarHBondContact O-N 3.27Å; L501-N504 VanDerWaalsContact O-N 3.17Å; N504-W508 VanDerWaalsContact O-CB 3.23Å; N504-W508 WeakPolarHBondContact O-CB 3.32Å; N504-W508 PolarHBondContact O-N 3.15Å; N504-R548 VanDerWaalsContact OD1-CD 3.28Å; N504-R548 WeakPolarHBondContact OD1-CD 3.48Å; N504-R548 PolarHBondContact OD1-NH1 2.73Å; N504-R548 VanDerWaalsContact OD1-NH1 3.14Å; N504-V552 HydrophobicContact CB-CG2 3.58Å
505	V	93.4	Very high	89.9	Confident	35 Å²	35	16.9 Å²	16.9	21%	0.212	9%	0.093	C	C	.	.	H	α-helix	trans	-63.7	-46.5	174.3	177.9	0	0	0	0	110.7	F300 L501 L502 C503 W508 I509 V552	F300-V505 HydrophobicContact CD2-CG1 4.47Å; F300-V505 HydrophobicContact CE2-CB 4.46Å; F300-V505 HydrophobicContact CE2-CG1 3.83Å; L501-V505 HydrophobicContact CD2-CG2 4.17Å; L501-V505 WeakPolarHBondContact O-CG2 3.3Å; L501-V505 PolarHBondContact O-N 2.73Å; L502-V505 PolarHBondContact O-N 2.96Å; C503-V505 VanDerWaalsContact C-N 3.34Å; V505-W508 WeakPolarHBondContact O-CB 3.36Å; V505-W508 PolarHBondContact O-N 3.27Å; V505-I509 HydrophobicContact CG1-CD1 3.93Å; V505-I509 HydrophobicContact CG1-CG1 4.42Å; V505-I509 WeakPolarHBondContact O-CG1 3.47Å; V505-I509 PolarHBondContact O-N 3.47Å; V505-V552 HydrophobicContact CG2-CG1 4.09Å; V505-V552 HydrophobicContact CG2-CG2 3.72Å
506	I	94.8	Very high	89.7	Confident	0 Å²	0	17.5 Å²	17.5	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-68.3	-39.5	179.6	-173	55.6	0	0	0	112.5	F300 L304 L502 C503 W508 I509 M510	F300-I506 HydrophobicContact CD2-CB 3.82Å; F300-I506 HydrophobicContact CE2-CB 4.41Å; L304-I506 HydrophobicContact CD2-CD1 3.81Å; L304-I506 HydrophobicContact CG-CD1 3.93Å; L502-I506 PolarHBondContact O-N 3.05Å; C503-I506 WeakPolarHBondContact O-CG2 3.49Å; C503-I506 PolarHBondContact O-N 3.31Å; I506-W508 PolarHBondContact O-N 2.95Å; I506-I509 PolarHBondContact O-N 3.36Å; I506-M510 HydrophobicContact CD1-CE 4.24Å; I506-M510 HydrophobicContact CG1-CE 4.03Å; I506-M510 WeakPolarHBondContact O-CG 3.45Å; I506-M510 PolarHBondContact O-N 3.32Å
507	L	94	Very high	89.4	Confident	10 Å²	10	16.8 Å²	16.8	5%	0.052	9%	0.091	C	C	.	.	H	α-helix	trans	-68.6	-16.1	174.2	-66.8	175.5	0	0	0	113.1	N332 L336 C503 P511	N332-L507 WeakPolarHBondContact OD1-CD2 3.29Å; L336-L507 HydrophobicContact CD2-CD1 4.01Å; C503-L507 WeakPolarHBondContact O-CB 3.32Å; C503-L507 VanDerWaalsContact O-CG 3.26Å; C503-L507 WeakPolarHBondContact O-CG 3.43Å; C503-L507 PolarHBondContact O-N 3.48Å; C503-L507 VanDerWaalsContact O-N 3.08Å; L507-P511 WeakPolarHBondContact O-CD 3.43Å; L507-P511 WeakPolarHBondContact O-CG 3.2Å
508	W	92.8	Very high	89	Confident	28 Å²	28	17.4 Å²	17.4	11%	0.106	9%	0.094	C	C	.	.	H	α-helix	trans	-83.5	-46.6	170	172	66.9	0	0	0	111.9	F110 N504 V505 I506 M510 P511 A512 I545 R548 M549	F110-W508 HydrophobicContact CE1-CZ2 4.28Å; F110-W508 AromaticContact CZ-CZ2 3.79Å; F110-W508 HydrophobicContact CZ-CZ2 3.79Å; N504-W508 VanDerWaalsContact O-CB 3.23Å; N504-W508 WeakPolarHBondContact O-CB 3.32Å; N504-W508 PolarHBondContact O-N 3.15Å; V505-W508 WeakPolarHBondContact O-CB 3.36Å; V505-W508 PolarHBondContact O-N 3.27Å; I506-W508 PolarHBondContact O-N 2.95Å; W508-M510 VanDerWaalsContact C-N 3.34Å; W508-M510 PolarHBondContact O-N 2.93Å; W508-P511 WeakPolarHBondContact O-CD 3.36Å; W508-P511 WeakPolarHBondContact O-CG 3.34Å; W508-A512 HydrophobicContact CZ2-CB 4.43Å; W508-A512 WeakPolarHBondContact O-CB 3.48Å; W508-A512 PolarHBondContact O-N 2.92Å; W508-I545 VanDerWaalsContact NE1-CG2 3.27Å; W508-R548 HydrophobicContact CB-CB 3.72Å; W508-R548 HydrophobicContact CB-CG 4.48Å; W508-R548 HydrophobicContact CG-CB 4.36Å; W508-M549 VanDerWaalsContact CD1-CG 3.4Å; W508-M549 HydrophobicContact CD2-CG 3.98Å; W508-M549 HydrophobicContact CD2-SD 3.54Å; W508-M549 VanDerWaalsContact CD2-SD 3.54Å; W508-M549 HydrophobicContact CE3-SD 4.02Å; W508-M549 HydrophobicContact CG-CG 3.91Å; W508-M549 HydrophobicContact CG-SD 3.98Å; W508-M549 HydrophobicContact CH2-SD 4.18Å; W508-M549 HydrophobicContact CZ2-CE 4.23Å; W508-M549 HydrophobicContact CZ2-CG 4.21Å; W508-M549 HydrophobicContact CZ2-SD 3.72Å; W508-M549 HydrophobicContact CZ3-SD 4.32Å
509	I	89.8	Confident	88.6	Confident	27 Å²	27	18.1 Å²	18.1	14%	0.138	10%	0.096	C	C	.	.	H	α-helix	trans	-58.2	-45.6	-177.8	-71.6	170.6	0	0	0	111.1	F300 L304 V505 I506 A512 F513	F300-I509 HydrophobicContact CE2-CD1 3.87Å; F300-I509 HydrophobicContact CZ-CD1 4.16Å; L304-I509 HydrophobicContact CD2-CG2 4.37Å; V505-I509 HydrophobicContact CG1-CD1 3.93Å; V505-I509 HydrophobicContact CG1-CG1 4.42Å; V505-I509 WeakPolarHBondContact O-CG1 3.47Å; V505-I509 PolarHBondContact O-N 3.47Å; I506-I509 PolarHBondContact O-N 3.36Å; I509-A512 PolarHBondContact O-N 3.41Å; I509-F513 HydrophobicContact CG2-CD2 3.94Å; I509-F513 HydrophobicContact CG2-CE2 4.47Å; I509-F513 WeakPolarHBondContact O-CD2 3.38Å; I509-F513 PolarHBondContact O-N 2.93Å
510	M	90.7	Very high	88	Confident	0 Å²	0	19.3 Å²	19.3	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-52.3	-62.7	-176.5	-72.3	177	172.5	0	0	113	G303 F307 Y328 F331 I506 W508 A512 A515	G303-M510 WeakPolarHBondContact O-CE 3.43Å; F307-M510 HydrophobicContact CB-CE 4.34Å; F307-M510 HydrophobicContact CB-CG 4.18Å; F307-M510 HydrophobicContact CD2-CB 4.48Å; F307-M510 HydrophobicContact CD2-CG 4.28Å; Y328-M510 HydrophobicContact CE2-CB 4.45Å; Y328-M510 HydrophobicContact CE2-CG 4.49Å; Y328-M510 HydrophobicContact CE2-SD 3.87Å; F331-M510 HydrophobicContact CD1-CE 3.78Å; F331-M510 HydrophobicContact CE1-CE 3.46Å; F331-M510 VanDerWaalsContact CE1-CE 3.46Å; F331-M510 HydrophobicContact CE1-SD 4.32Å; F331-M510 HydrophobicContact CZ-CE 4.39Å; I506-M510 HydrophobicContact CD1-CE 4.24Å; I506-M510 HydrophobicContact CG1-CE 4.03Å; I506-M510 WeakPolarHBondContact O-CG 3.45Å; I506-M510 PolarHBondContact O-N 3.32Å; W508-M510 VanDerWaalsContact C-N 3.34Å; W508-M510 PolarHBondContact O-N 2.93Å; M510-A512 VanDerWaalsContact C-N 3.35Å; M510-A512 PolarHBondContact O-N 2.69Å; M510-A515 HydrophobicContact CB-CB 4.42Å; M510-A515 VanDerWaalsContact O-CB 3.31Å; M510-A515 WeakPolarHBondContact O-CB 3.35Å; M510-A515 PolarHBondContact O-N 2.59Å
511	P	87.7	Confident	87.3	Confident	17 Å²	17	19.3 Å²	19.3	11%	0.11	11%	0.105	C	C	.	.	H	α-helix	trans	-69.5	-28.8	179.9	27.6	-35.9	0	0	0	113.6	L507 W508 F513 L541 I545	L507-P511 WeakPolarHBondContact O-CD 3.43Å; L507-P511 WeakPolarHBondContact O-CG 3.2Å; W508-P511 WeakPolarHBondContact O-CD 3.36Å; W508-P511 WeakPolarHBondContact O-CG 3.34Å; P511-F513 VanDerWaalsContact C-N 3.34Å; P511-F513 PolarHBondContact O-N 2.81Å; P511-L541 HydrophobicContact CB-CD1 4.14Å; P511-I545 HydrophobicContact CB-CD1 4.3Å; P511-I545 HydrophobicContact CB-CG1 4.08Å; P511-I545 HydrophobicContact CG-CG1 4.08Å
512	A	82.9	Confident	86.8	Confident	4 Å²	4	21.8 Å²	21.8	3%	0.033	12%	0.122	C	C	.	.	H	α-helix	trans	-67.6	-32.7	-179.3	0	0	0	0	0	113.1	W508 I509 M510 I545	W508-A512 HydrophobicContact CZ2-CB 4.43Å; W508-A512 WeakPolarHBondContact O-CB 3.48Å; W508-A512 PolarHBondContact O-N 2.92Å; I509-A512 PolarHBondContact O-N 3.41Å; M510-A512 VanDerWaalsContact C-N 3.35Å; M510-A512 PolarHBondContact O-N 2.69Å; A512-I545 HydrophobicContact CB-CG2 4.31Å
513	F	80.9	Confident	86.4	Confident	77 Å²	77	21.2 Å²	21.2	34%	0.338	12%	0.12	S	C	.	.	T	Hydrogen-bonded Turn	trans	-102.9	14.9	-176.6	-74.9	-87.1	0	0	0	114.4	Y242 F246 F307 I509 P511	Y242-F513 PolarHBondContact OH-O 3.39Å; F246-F513 HydrophobicContact CZ-CD1 4.11Å; F246-F513 HydrophobicContact CZ-CE1 4.01Å; F246-F513 HydrophobicContact CZ-CZ 4.47Å; F307-F513 HydrophobicContact CE1-CB 4.39Å; F307-F513 HydrophobicContact CE2-CB 4.26Å; F307-F513 HydrophobicContact CZ-CB 3.63Å; I509-F513 HydrophobicContact CG2-CD2 3.94Å; I509-F513 HydrophobicContact CG2-CE2 4.47Å; I509-F513 WeakPolarHBondContact O-CD2 3.38Å; I509-F513 PolarHBondContact O-N 2.93Å; P511-F513 VanDerWaalsContact C-N 3.34Å; P511-F513 PolarHBondContact O-N 2.81Å
514	G	73.1	Confident	86.1	Confident	29 Å²	29	21.2 Å²	21.2	30%	0.299	12%	0.12	S	C	.	.	T	Hydrogen-bonded Turn	trans	113	-6.7	167.6	0	0	0	0	0	115.9	E311 R516	E311-G514 VanDerWaalsContact OE1-C 3.3Å; G514-R516 PolarHBondContact O-N 3.37Å
515	A	78.6	Confident	85.7	Confident	1 Å²	1	21.6 Å²	21.6	1%	0.008	12%	0.122	C	C	.	.			trans	-74	96.9	177.8	0	0	0	0	0	110.7	F307 Y310 E311 Y328 M510 P517	F307-A515 HydrophobicContact CD2-CB 3.7Å; F307-A515 HydrophobicContact CE2-CB 3.73Å; Y310-A515 HydrophobicContact CD1-CB 3.64Å; Y310-A515 HydrophobicContact CE1-CB 3.73Å; E311-A515 WeakPolarHBondContact OE1-CA 3.4Å; E311-A515 PolarHBondContact OE1-N 3.49Å; Y328-A515 HydrophobicContact CE2-CB 4.23Å; M510-A515 HydrophobicContact CB-CB 4.42Å; M510-A515 VanDerWaalsContact O-CB 3.31Å; M510-A515 WeakPolarHBondContact O-CB 3.35Å; M510-A515 PolarHBondContact O-N 2.59Å; A515-P517 WeakPolarHBondContact O-CD 3.09Å
516	R	83.5	Confident	85.4	Confident	24 Å²	24	25.6 Å²	25.6	9%	0.091	14%	0.142	C	C	.	.			trans	-122.4	79.5	-177.5	-59.3	-168.9	-174.1	-179.3	9.4	110.8	E191 Y310 G514 H518 F519 N538 L541	E191-R516 IonicContact OE1-CZ 3.97Å; E191-R516 IonicContact OE1-NH1 3.87Å; E191-R516 PolarHBondContact OE1-NH1 3.33Å; E191-R516 IonicContact OE1-NH2 2.67Å; E191-R516 PolarHBondContact OE1-NH2 3.49Å; E191-R516 IonicContact OE2-NH1 3.69Å; Y310-R516 PolarHBondContact OH-O 2.93Å; G514-R516 PolarHBondContact O-N 3.37Å; R516-H518 PolarHBondContact O-N 3.35Å; R516-H518 VanDerWaalsContact O-N 3.09Å; R516-F519 HydrophobicContact CB-CD2 3.69Å; R516-F519 HydrophobicContact CB-CE2 4.3Å; R516-F519 HydrophobicContact CG-CD2 4.46Å; R516-F519 PolarHBondContact O-N 3.48Å; R516-F519 VanDerWaalsContact O-N 3.09Å; R516-N538 PolarHBondContact NH1-OD1 3.48Å; R516-L541 HydrophobicContact CG-CD2 3.94Å
517	P	84.6	Confident	85.2	Confident	2 Å²	2	29.7 Å²	29.7	1%	0.013	16%	0.16	C	C	.	.	H	α-helix	trans	-57.9	-28.8	-179	28.3	-40	0	0	0	112.5	Y310 L325 Y328 Y329 A515 F519 S520 N521	Y310-P517 WeakPolarHBondContact OH-CA 3.28Å; L325-P517 HydrophobicContact CD2-CB 3.76Å; Y328-P517 HydrophobicContact CD1-CB 4.15Å; Y328-P517 HydrophobicContact CD1-CG 4.04Å; Y328-P517 HydrophobicContact CE1-CB 4.14Å; Y328-P517 HydrophobicContact CE1-CG 3.52Å; Y329-P517 HydrophobicContact CE2-CB 4.25Å; A515-P517 WeakPolarHBondContact O-CD 3.09Å; P517-F519 PolarHBondContact O-N 2.92Å; P517-F519 VanDerWaalsContact O-N 3.11Å; P517-S520 CarbonylContact O-C 3.59Å; P517-S520 PolarHBondContact O-N 3.29Å; P517-N521 WeakPolarHBondContact O-CB 3.32Å; P517-N521 PolarHBondContact O-N 3.47Å
518	H	83.5	Confident	85	Confident	13 Å²	13	31.5 Å²	31.5	6%	0.06	17%	0.167	C	C	.	.	H	α-helix	trans	-55.1	-28.1	177.3	-49.3	94.6	0	0	0	113.9	R516 W533 V537	R516-H518 PolarHBondContact O-N 3.35Å; R516-H518 VanDerWaalsContact O-N 3.09Å; H518-W533 HydrophobicContact CB-CZ2 3.93Å; H518-W533 AromaticContact CD2-CZ2 3.99Å; H518-W533 PolarHBondContact O-NE1 3.23Å; H518-V537 HydrophobicContact CB-CG1 4.08Å; H518-V537 HydrophobicContact CB-CG2 3.85Å
519	F	82	Confident	84.7	Confident	38 Å²	38	31.8 Å²	31.8	17%	0.167	18%	0.178	C	C	.	.	H	α-helix	trans	-92.7	-16.3	176.4	-66	-66.4	0	0	0	113.6	R516 P517 Y530 A534 V537 N538	R516-F519 HydrophobicContact CB-CD2 3.69Å; R516-F519 HydrophobicContact CB-CE2 4.3Å; R516-F519 HydrophobicContact CG-CD2 4.46Å; R516-F519 PolarHBondContact O-N 3.48Å; R516-F519 VanDerWaalsContact O-N 3.09Å; P517-F519 PolarHBondContact O-N 2.92Å; P517-F519 VanDerWaalsContact O-N 3.11Å; F519-Y530 HydrophobicContact CD1-CE2 4.45Å; F519-A534 HydrophobicContact CE1-CB 3.71Å; F519-A534 HydrophobicContact CZ-CB 4.46Å; F519-V537 HydrophobicContact CD2-CG1 4.44Å; F519-V537 HydrophobicContact CE1-CB 4.39Å; F519-V537 HydrophobicContact CE1-CG1 4.49Å; F519-V537 HydrophobicContact CE2-CB 4.26Å; F519-V537 HydrophobicContact CE2-CG1 3.53Å; F519-V537 HydrophobicContact CZ-CB 3.76Å; F519-V537 HydrophobicContact CZ-CG1 3.56Å; F519-N538 WeakPolarHBondContact CZ-OD1 3.28Å
520	S	80.7	Confident	84.5	Confident	31 Å²	31	31.8 Å²	31.8	22%	0.217	18%	0.177	C	C	.	.	H	α-helix	trans	-95.6	-23.3	178.3	-57.9	0	0	0	0	112.4	Y310 P517	Y310-S520 PolarHBondContact OH-OG 3.48Å; P517-S520 CarbonylContact O-C 3.59Å; P517-S520 PolarHBondContact O-N 3.29Å
521	N	81.8	Confident	84.1	Confident	1 Å²	1	35.3 Å²	35.3	1%	0.005	20%	0.201	C	C	.	.			trans	-80	129.1	173.4	-168.8	12.6	0	0	0	109.3	Y329 L399 P517 V523 E524	Y329-N521 PolarHBondContact OH-ND2 3.42Å; L399-N521 WeakPolarHBondContact CD2-OD1 3.2Å; P517-N521 WeakPolarHBondContact O-CB 3.32Å; P517-N521 PolarHBondContact O-N 3.47Å; N521-V523 WeakPolarHBondContact OD1-CG2 2.98Å; N521-V523 PolarHBondContact OD1-N 3.45Å; N521-E524 PolarHBondContact ND2-OE2 2.84Å
522	T	83.6	Confident	84.1	Confident	77 Å²	77	39 Å²	39	47%	0.472	22%	0.219	S	C	.	.	H	α-helix	trans	-85.8	-17.4	-178.3	61.8	0	0	0	0	112.4	E524 V525 D526	T522-E524 PolarHBondContact O-N 2.79Å; T522-V525 PolarHBondContact O-N 2.99Å; T522-V525 VanDerWaalsContact O-N 3.16Å; T522-D526 WeakPolarHBondContact O-CB 3.3Å; T522-D526 PolarHBondContact O-N 3.23Å
523	V	85.6	Confident	84.4	Confident	31 Å²	31	38.8 Å²	38.8	19%	0.188	22%	0.218	C	C	.	.	H	α-helix	trans	-54.4	-52.9	-172.9	175.9	0	0	0	0	112.3	V390 A400 N521 F527	V390-V523 HydrophobicContact CG2-CG1 3.89Å; A400-V523 HydrophobicContact CB-CG2 4.28Å; N521-V523 WeakPolarHBondContact OD1-CG2 2.98Å; N521-V523 PolarHBondContact OD1-N 3.45Å; V523-F527 PolarHBondContact O-N 2.95Å
524	E	89.3	Confident	84.7	Confident	0 Å²	0	35.1 Å²	35.1	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-76.1	-30.5	-179	-58.6	98.8	136.4	0	0	112.7	S386 A389 N521 T522 F527 Y528 W533	S386-E524 PolarHBondContact OG-OE1 2.91Å; A389-E524 HydrophobicContact CB-CG 4.11Å; N521-E524 PolarHBondContact ND2-OE2 2.84Å; T522-E524 PolarHBondContact O-N 2.79Å; E524-F527 PolarHBondContact O-N 3.23Å; E524-Y528 PolarHBondContact O-N 2.97Å; E524-W533 HydrophobicContact CB-CD2 3.65Å; E524-W533 VanDerWaalsContact CB-CE2 3.42Å; E524-W533 HydrophobicContact CB-CE3 4.08Å; E524-W533 HydrophobicContact CB-CG 4.12Å; E524-W533 HydrophobicContact CB-CH2 4.08Å; E524-W533 HydrophobicContact CB-CZ2 3.64Å; E524-W533 HydrophobicContact CB-CZ3 4.29Å; E524-W533 HydrophobicContact CG-CD2 4.48Å; E524-W533 HydrophobicContact CG-CH2 3.85Å; E524-W533 HydrophobicContact CG-CZ2 3.63Å; E524-W533 HydrophobicContact CG-CZ3 4.36Å
525	V	87.4	Confident	85.2	Confident	9 Å²	9	35.3 Å²	35.3	6%	0.055	20%	0.201	C	C	.	.	H	α-helix	trans	-65.9	-42.4	176.9	176.3	0	0	0	0	110.8	Y199 T522 F527 G529 Y530	Y199-V525 HydrophobicContact CE1-CG1 4.37Å; Y199-V525 HydrophobicContact CE2-CG1 4.4Å; T522-V525 PolarHBondContact O-N 2.99Å; T522-V525 VanDerWaalsContact O-N 3.16Å; V525-F527 VanDerWaalsContact C-N 3.3Å; V525-F527 PolarHBondContact O-N 3.34Å; V525-G529 CarbonylContact O-C 3.5Å; V525-G529 WeakPolarHBondContact O-CA 3.27Å; V525-G529 PolarHBondContact O-N 3.26Å; V525-Y530 HydrophobicContact CG1-CD2 4.01Å; V525-Y530 HydrophobicContact CG2-CD2 4.32Å
526	D	86.4	Confident	85.8	Confident	119 Å²	119	36.1 Å²	36.1	64%	0.636	21%	0.205	S	C	*	.	H	α-helix	trans	-69.2	-29.8	179.6	-66.5	-24.2	0	0	0	111.6	T522	T522-D526 WeakPolarHBondContact O-CB 3.3Å; T522-D526 PolarHBondContact O-N 3.23Å
527	F	89.7	Confident	86.1	Confident	86 Å²	86	35 Å²	35	38%	0.377	20%	0.2	S	C	.	.	H	α-helix	trans	-84.6	-50	-179.7	-173.7	-96.3	0	0	0	113.5	V388 A389 A392 V523 E524 V525	V388-F527 HydrophobicContact CG1-CE1 4.34Å; A389-F527 HydrophobicContact CB-CB 3.99Å; A389-F527 HydrophobicContact CB-CD1 3.86Å; A389-F527 HydrophobicContact CB-CG 3.97Å; A392-F527 HydrophobicContact CB-CE2 3.91Å; A392-F527 HydrophobicContact CB-CZ 3.9Å; V523-F527 PolarHBondContact O-N 2.95Å; E524-F527 PolarHBondContact O-N 3.23Å; V525-F527 VanDerWaalsContact C-N 3.3Å; V525-F527 PolarHBondContact O-N 3.34Å
528	Y	90.1	Very high	86.1	Confident	48 Å²	48	34.9 Å²	34.9	19%	0.188	20%	0.2	C	C	.	.	H	α-helix	trans	-94	-16.1	-175.6	-71	-63.7	0	0	0	114.1	Y385 V388 A389 E524 L532 W533	Y385-Y528 AromaticContact CD1-CE1 4Å; Y385-Y528 HydrophobicContact CD1-CE1 4Å; Y385-Y528 AromaticContact CD1-CE2 3.97Å; Y385-Y528 HydrophobicContact CD1-CE2 3.97Å; Y385-Y528 AromaticContact CD1-CZ 3.58Å; Y385-Y528 HydrophobicContact CE1-CE1 4.38Å; Y385-Y528 WeakPolarHBondContact O-CE2 3.5Å; Y385-Y528 PolarHBondContact O-OH 2.82Å; V388-Y528 WeakPolarHBondContact CB-OH 3.43Å; V388-Y528 WeakPolarHBondContact CG1-OH 3.24Å; A389-Y528 HydrophobicContact CB-CD2 4.39Å; A389-Y528 HydrophobicContact CB-CE2 3.81Å; E524-Y528 PolarHBondContact O-N 2.97Å; Y528-L532 HydrophobicContact CD1-CD2 4.06Å; Y528-W533 HydrophobicContact CD2-CE3 4.28Å
529	G	87.4	Confident	86.3	Confident	34 Å²	34	37.3 Å²	37.3	35%	0.351	21%	0.213	S	C	.	.			trans	78.5	146.4	-164.7	0	0	0	0	0	111.8	V525 S531 L532 W533	V525-G529 CarbonylContact O-C 3.5Å; V525-G529 WeakPolarHBondContact O-CA 3.27Å; V525-G529 PolarHBondContact O-N 3.26Å; G529-S531 PolarHBondContact O-N 2.79Å; G529-L532 PolarHBondContact O-N 3.19Å; G529-W533 PolarHBondContact O-N 3.08Å; G529-W533 VanDerWaalsContact O-N 3.16Å
530	Y	85.2	Confident	86.8	Confident	27 Å²	27	36.3 Å²	36.3	11%	0.106	21%	0.21	C	C	.	.	H	α-helix	trans	-55.8	-45.5	-173.4	-170.6	-83.5	0	0	0	113.4	Q195 S196 Y199 F519 V525 L532 W533 A534	Q195-Y530 HydrophobicContact CB-CE1 3.94Å; Q195-Y530 VanDerWaalsContact CB-OH 3.31Å; Q195-Y530 WeakPolarHBondContact CB-OH 3.49Å; Q195-Y530 WeakPolarHBondContact O-CE1 3.4Å; Q195-Y530 PolarHBondContact O-OH 3.06Å; S196-Y530 VanDerWaalsContact CA-CE1 3.42Å; Y199-Y530 HydrophobicContact CD1-CD1 4.4Å; Y199-Y530 AromaticContact CD1-CD2 3.57Å; Y199-Y530 HydrophobicContact CD1-CD2 3.57Å; Y199-Y530 HydrophobicContact CD1-CE2 4.25Å; Y199-Y530 AromaticContact CD1-CG 3.63Å; Y199-Y530 HydrophobicContact CD1-CG 3.63Å; Y199-Y530 AromaticContact CD2-CD2 3.46Å; Y199-Y530 HydrophobicContact CD2-CD2 3.46Å; Y199-Y530 VanDerWaalsContact CD2-CD2 3.46Å; Y199-Y530 AromaticContact CD2-CE2 3.49Å; Y199-Y530 HydrophobicContact CD2-CE2 3.49Å; Y199-Y530 VanDerWaalsContact CD2-CE2 3.49Å; Y199-Y530 HydrophobicContact CD2-CG 4.34Å; Y199-Y530 AromaticContact CE1-CD2 3.99Å; Y199-Y530 HydrophobicContact CE1-CD2 3.99Å; Y199-Y530 HydrophobicContact CE1-CG 4.19Å; Y199-Y530 AromaticContact CE2-CD2 3.89Å; Y199-Y530 HydrophobicContact CE2-CD2 3.89Å; Y199-Y530 HydrophobicContact CE2-CE2 4.24Å; Y199-Y530 HydrophobicContact CG-CD1 4.33Å; Y199-Y530 AromaticContact CG-CD2 3.28Å; Y199-Y530 HydrophobicContact CG-CD2 3.28Å; Y199-Y530 AromaticContact CG-CE2 3.49Å; Y199-Y530 HydrophobicContact CG-CE2 3.49Å; Y199-Y530 VanDerWaalsContact CG-CE2 3.49Å; Y199-Y530 AromaticContact CG-CG 3.72Å; Y199-Y530 HydrophobicContact CG-CG 3.72Å; F519-Y530 HydrophobicContact CD1-CE2 4.45Å; V525-Y530 HydrophobicContact CG1-CD2 4.01Å; V525-Y530 HydrophobicContact CG2-CD2 4.32Å; Y530-L532 PolarHBondContact O-N 3.21Å; Y530-W533 PolarHBondContact O-N 3.06Å; Y530-A534 HydrophobicContact CD1-CB 4.17Å; Y530-A534 HydrophobicContact CE1-CB 3.9Å; Y530-A534 WeakPolarHBondContact O-CB 3.32Å; Y530-A534 PolarHBondContact O-N 2.89Å
531	S	82.9	Confident	87.2	Confident	74 Å²	74	35.1 Å²	35.1	52%	0.517	20%	0.201	S	C	.	.	H	α-helix	trans	-65.1	-41.1	-173.5	-53.9	0	0	0	0	113.2	S196 G529 A535	S196-S531 PolarHBondContact OG-OG 3.02Å; G529-S531 PolarHBondContact O-N 2.79Å; S531-A535 WeakPolarHBondContact O-CB 3.27Å; S531-A535 PolarHBondContact O-N 3.2Å
532	L	86.2	Confident	87.5	Confident	93 Å²	93	35.5 Å²	35.5	49%	0.487	20%	0.204	S	C	.	.	H	α-helix	trans	-70.5	-45.5	178	177.4	60	0	0	0	110.6	Y528 G529 Y530 A534 A535 I536	Y528-L532 HydrophobicContact CD1-CD2 4.06Å; G529-L532 PolarHBondContact O-N 3.19Å; Y530-L532 PolarHBondContact O-N 3.21Å; L532-A534 PolarHBondContact O-N 3.32Å; L532-A535 PolarHBondContact O-N 3.32Å; L532-I536 HydrophobicContact CD1-CD1 4.13Å; L532-I536 HydrophobicContact CD1-CG1 4.46Å; L532-I536 HydrophobicContact CG-CD1 4.04Å; L532-I536 WeakPolarHBondContact O-CG1 2.96Å; L532-I536 PolarHBondContact O-N 3.25Å
533	W	90.6	Very high	87.8	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-62.6	-43.6	179.1	-177.9	-124.5	0	0	0	112.2	I382 S386 H518 E524 Y528 G529 Y530 A535 I536 V537	I382-W533 HydrophobicContact CG2-CH2 4.03Å; S386-W533 WeakPolarHBondContact OG-CH2 3.47Å; H518-W533 HydrophobicContact CB-CZ2 3.93Å; H518-W533 AromaticContact CD2-CZ2 3.99Å; H518-W533 PolarHBondContact O-NE1 3.23Å; E524-W533 HydrophobicContact CB-CD2 3.65Å; E524-W533 VanDerWaalsContact CB-CE2 3.42Å; E524-W533 HydrophobicContact CB-CE3 4.08Å; E524-W533 HydrophobicContact CB-CG 4.12Å; E524-W533 HydrophobicContact CB-CH2 4.08Å; E524-W533 HydrophobicContact CB-CZ2 3.64Å; E524-W533 HydrophobicContact CB-CZ3 4.29Å; E524-W533 HydrophobicContact CG-CD2 4.48Å; E524-W533 HydrophobicContact CG-CH2 3.85Å; E524-W533 HydrophobicContact CG-CZ2 3.63Å; E524-W533 HydrophobicContact CG-CZ3 4.36Å; Y528-W533 HydrophobicContact CD2-CE3 4.28Å; G529-W533 PolarHBondContact O-N 3.08Å; G529-W533 VanDerWaalsContact O-N 3.16Å; Y530-W533 PolarHBondContact O-N 3.06Å; W533-A535 PolarHBondContact O-N 3.09Å; W533-I536 HydrophobicContact CE3-CB 4.47Å; W533-I536 HydrophobicContact CZ3-CG2 4.33Å; W533-I536 PolarHBondContact O-N 2.85Å; W533-V537 HydrophobicContact CD2-CG2 3.82Å; W533-V537 VanDerWaalsContact CE2-CG2 3.5Å; W533-V537 HydrophobicContact CE3-CG2 4.2Å; W533-V537 HydrophobicContact CG-CG2 4.39Å; W533-V537 HydrophobicContact CH2-CG2 4.06Å; W533-V537 HydrophobicContact CZ2-CG2 3.67Å; W533-V537 HydrophobicContact CZ3-CG2 4.3Å; W533-V537 WeakPolarHBondContact O-CG2 3.24Å; W533-V537 PolarHBondContact O-N 2.74Å
534	A	85.9	Confident	88	Confident	1 Å²	1	33.3 Å²	33.3	1%	0.008	19%	0.186	C	C	.	.	H	α-helix	trans	-61.7	-42.3	177	0	0	0	0	0	112.7	F519 Y530 L532 I536 V537 N538	F519-A534 HydrophobicContact CE1-CB 3.71Å; F519-A534 HydrophobicContact CZ-CB 4.46Å; Y530-A534 HydrophobicContact CD1-CB 4.17Å; Y530-A534 HydrophobicContact CE1-CB 3.9Å; Y530-A534 WeakPolarHBondContact O-CB 3.32Å; Y530-A534 PolarHBondContact O-N 2.89Å; L532-A534 PolarHBondContact O-N 3.32Å; A534-I536 PolarHBondContact O-N 3.05Å; A534-V537 PolarHBondContact O-N 3.4Å; A534-N538 WeakPolarHBondContact O-CB 3.38Å; A534-N538 VanDerWaalsContact O-CG 3.28Å; A534-N538 PolarHBondContact O-N 3.32Å; A534-N538 PolarHBondContact O-ND2 2.99Å; A534-N538 VanDerWaalsContact O-ND2 3.14Å
535	A	84.9	Confident	88	Confident	33 Å²	33	33.5 Å²	33.5	27%	0.273	19%	0.187	S	C	.	.	H	α-helix	trans	-60.8	-45.4	174.9	0	0	0	0	0	111.7	S531 L532 W533 I539	S531-A535 WeakPolarHBondContact O-CB 3.27Å; S531-A535 PolarHBondContact O-N 3.2Å; L532-A535 PolarHBondContact O-N 3.32Å; W533-A535 PolarHBondContact O-N 3.09Å; A535-I539 WeakPolarHBondContact O-CB 3.24Å; A535-I539 WeakPolarHBondContact O-CD1 3.41Å; A535-I539 WeakPolarHBondContact O-CG1 3.44Å; A535-I539 PolarHBondContact O-N 2.8Å
536	I	90	Very high	88	Confident	17 Å²	17	33.6 Å²	33.6	9%	0.087	19%	0.187	C	C	.	.	H	α-helix	trans	-60.5	-51.4	177.7	-67.6	164.5	0	0	0	110.4	Y385 L532 W533 A534 I539 C540	Y385-I536 HydrophobicContact CD1-CD1 3.79Å; Y385-I536 HydrophobicContact CD2-CD1 4.17Å; Y385-I536 HydrophobicContact CD2-CG2 3.94Å; Y385-I536 HydrophobicContact CE1-CD1 3.67Å; Y385-I536 HydrophobicContact CE2-CD1 4.08Å; Y385-I536 HydrophobicContact CE2-CG1 4.49Å; Y385-I536 HydrophobicContact CE2-CG2 4.31Å; Y385-I536 HydrophobicContact CG-CD1 4.06Å; Y385-I536 HydrophobicContact CG-CG2 4.44Å; L532-I536 HydrophobicContact CD1-CD1 4.13Å; L532-I536 HydrophobicContact CD1-CG1 4.46Å; L532-I536 HydrophobicContact CG-CD1 4.04Å; L532-I536 WeakPolarHBondContact O-CG1 2.96Å; L532-I536 PolarHBondContact O-N 3.25Å; W533-I536 HydrophobicContact CE3-CB 4.47Å; W533-I536 HydrophobicContact CZ3-CG2 4.33Å; W533-I536 PolarHBondContact O-N 2.85Å; A534-I536 PolarHBondContact O-N 3.05Å; I536-I539 PolarHBondContact O-N 2.68Å; I536-C540 WeakPolarHBondContact O-CB 3.39Å; I536-C540 PolarHBondContact O-N 2.96Å; I536-C540 PolarHBondContact O-SG 3.15Å; I536-C540 VanDerWaalsContact O-SG 3.41Å
537	V	89.8	Confident	88.3	Confident	0 Å²	0	27.9 Å²	27.9	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-63.2	-46	-177.6	175.1	0	0	0	0	111.1	H518 F519 W533 A534 I539 C540 L541	H518-V537 HydrophobicContact CB-CG1 4.08Å; H518-V537 HydrophobicContact CB-CG2 3.85Å; F519-V537 HydrophobicContact CD2-CG1 4.44Å; F519-V537 HydrophobicContact CE1-CB 4.39Å; F519-V537 HydrophobicContact CE1-CG1 4.49Å; F519-V537 HydrophobicContact CE2-CB 4.26Å; F519-V537 HydrophobicContact CE2-CG1 3.53Å; F519-V537 HydrophobicContact CZ-CB 3.76Å; F519-V537 HydrophobicContact CZ-CG1 3.56Å; W533-V537 HydrophobicContact CD2-CG2 3.82Å; W533-V537 VanDerWaalsContact CE2-CG2 3.5Å; W533-V537 HydrophobicContact CE3-CG2 4.2Å; W533-V537 HydrophobicContact CG-CG2 4.39Å; W533-V537 HydrophobicContact CH2-CG2 4.06Å; W533-V537 HydrophobicContact CZ2-CG2 3.67Å; W533-V537 HydrophobicContact CZ3-CG2 4.3Å; W533-V537 WeakPolarHBondContact O-CG2 3.24Å; W533-V537 PolarHBondContact O-N 2.74Å; A534-V537 PolarHBondContact O-N 3.4Å; V537-I539 VanDerWaalsContact C-N 3.33Å; V537-I539 PolarHBondContact O-N 3.37Å; V537-C540 PolarHBondContact O-N 3.3Å; V537-L541 HydrophobicContact CG1-CB 4.27Å; V537-L541 HydrophobicContact CG1-CD2 4.39Å; V537-L541 WeakPolarHBondContact O-CB 3.47Å; V537-L541 PolarHBondContact O-N 3.19Å
538	N	86.2	Confident	88.5	Confident	1 Å²	1	24.3 Å²	24.3	1%	0.005	14%	0.14	C	C	.	.	H	α-helix	trans	-70.3	-28.4	-178.4	-67.2	-31.6	0	0	0	112.9	V188 S192 Q195 R516 F519 A534 P542	V188-N538 HydrophobicContact CG1-CB 3.94Å; S192-N538 WeakPolarHBondContact CA-ND2 3.44Å; S192-N538 PolarHBondContact OG-ND2 3.31Å; Q195-N538 PolarHBondContact OE1-ND2 2.92Å; Q195-N538 PolarHBondContact OE1-OD1 3.48Å; R516-N538 PolarHBondContact NH1-OD1 3.48Å; F519-N538 WeakPolarHBondContact CZ-OD1 3.28Å; A534-N538 WeakPolarHBondContact O-CB 3.38Å; A534-N538 VanDerWaalsContact O-CG 3.28Å; A534-N538 PolarHBondContact O-N 3.32Å; A534-N538 PolarHBondContact O-ND2 2.99Å; A534-N538 VanDerWaalsContact O-ND2 3.14Å; N538-P542 WeakPolarHBondContact O-CD 3.27Å; N538-P542 VanDerWaalsContact O-CG 3.32Å; N538-P542 WeakPolarHBondContact O-CG 3.45Å
539	I	86.8	Confident	88.3	Confident	64 Å²	64	23.3 Å²	23.3	33%	0.328	14%	0.138	S	C	.	.	H	α-helix	trans	-71.5	-46	170.9	-69.3	167.4	0	0	0	110.6	W184 V188 A535 I536 V537 F543	W184-I539 HydrophobicContact CH2-CG2 4.3Å; W184-I539 HydrophobicContact CZ2-CG2 4.5Å; V188-I539 HydrophobicContact CG1-CB 4.4Å; V188-I539 HydrophobicContact CG1-CG1 3.56Å; A535-I539 WeakPolarHBondContact O-CB 3.24Å; A535-I539 WeakPolarHBondContact O-CD1 3.41Å; A535-I539 WeakPolarHBondContact O-CG1 3.44Å; A535-I539 PolarHBondContact O-N 2.8Å; I536-I539 PolarHBondContact O-N 2.68Å; V537-I539 VanDerWaalsContact C-N 3.33Å; V537-I539 PolarHBondContact O-N 3.37Å; I539-F543 WeakPolarHBondContact O-CD2 3.3Å; I539-F543 VanDerWaalsContact O-CE2 3.31Å; I539-F543 WeakPolarHBondContact O-CE2 3.03Å
540	C	91.3	Very high	88.3	Confident	16 Å²	16	22.2 Å²	22.2	11%	0.108	12%	0.124	C	C	.	.	H	α-helix	trans	-91.5	-30.2	-165.7	-70.2	0	0	0	0	114.9	G378 I382 I536 V537 F543 G544	G378-C540 WeakPolarHBondContact O-CB 3.33Å; I382-C540 HydrophobicContact CD1-CB 3.64Å; I382-C540 HydrophobicContact CG1-CB 3.54Å; I536-C540 WeakPolarHBondContact O-CB 3.39Å; I536-C540 PolarHBondContact O-N 2.96Å; I536-C540 PolarHBondContact O-SG 3.15Å; I536-C540 VanDerWaalsContact O-SG 3.41Å; V537-C540 PolarHBondContact O-N 3.3Å; C540-F543 PolarHBondContact O-N 3.25Å; C540-G544 PolarHBondContact O-N 3.13Å
541	L	89.3	Confident	88.5	Confident	7 Å²	7	21 Å²	21	4%	0.037	12%	0.119	C	C	.	.	H	α-helix	trans	-61.2	-42.7	-178.4	-175.8	69.2	0	0	0	112.7	I382 P511 R516 V537 F543 G544 I545	I382-L541 HydrophobicContact CD1-CB 4.29Å; P511-L541 HydrophobicContact CB-CD1 4.14Å; R516-L541 HydrophobicContact CG-CD2 3.94Å; V537-L541 HydrophobicContact CG1-CB 4.27Å; V537-L541 HydrophobicContact CG1-CD2 4.39Å; V537-L541 WeakPolarHBondContact O-CB 3.47Å; V537-L541 PolarHBondContact O-N 3.19Å; L541-F543 VanDerWaalsContact C-N 3.3Å; L541-F543 PolarHBondContact O-N 3.03Å; L541-G544 WeakPolarHBondContact O-CA 3.41Å; L541-G544 PolarHBondContact O-N 3.25Å; L541-I545 HydrophobicContact CG-CD1 4.4Å; L541-I545 PolarHBondContact O-N 3.44Å
542	P	88.4	Confident	88.9	Confident	8 Å²	8	18.7 Å²	18.7	5%	0.052	10%	0.102	C	C	.	.	H	α-helix	trans	-60.1	-37.6	178.2	-24.9	36.1	0	0	0	113.3	I248 E249 L252 N538 G544 I545 F546	I248-P542 HydrophobicContact CG2-CB 3.49Å; I248-P542 VanDerWaalsContact CG2-CB 3.49Å; I248-P542 HydrophobicContact CG2-CG 3.37Å; E249-P542 VanDerWaalsContact OE1-CA 3.24Å; E249-P542 WeakPolarHBondContact OE1-CA 3.44Å; E249-P542 WeakPolarHBondContact OE1-CB 3.08Å; L252-P542 HydrophobicContact CD1-CB 3.82Å; N538-P542 WeakPolarHBondContact O-CD 3.27Å; N538-P542 VanDerWaalsContact O-CG 3.32Å; N538-P542 WeakPolarHBondContact O-CG 3.45Å; P542-G544 PolarHBondContact O-N 2.96Å; P542-I545 PolarHBondContact O-N 2.85Å; P542-I545 VanDerWaalsContact O-N 3.16Å; P542-F546 WeakPolarHBondContact O-CB 3.47Å; P542-F546 PolarHBondContact O-N 3.04Å
543	F	90.2	Very high	88.7	Confident	58 Å²	58	14.7 Å²	14.7	25%	0.254	8%	0.081	S	C	.	.	H	α-helix	trans	-60.7	-34.2	173.3	-69.6	-78.5	0	0	0	112.2	W184 L252 A375 I539 C540 L541 Y547	W184-F543 AromaticContact CH2-CE2 3.77Å; W184-F543 HydrophobicContact CH2-CE2 3.77Å; W184-F543 AromaticContact CH2-CZ 3.92Å; W184-F543 HydrophobicContact CH2-CZ 3.92Å; W184-F543 AromaticContact CZ2-CE2 3.56Å; W184-F543 HydrophobicContact CZ2-CE2 3.56Å; W184-F543 AromaticContact CZ2-CZ 3.92Å; W184-F543 HydrophobicContact CZ2-CZ 3.92Å; L252-F543 HydrophobicContact CD2-CE1 4.47Å; A375-F543 CarbonylContact O-C 3.58Å; A375-F543 WeakPolarHBondContact O-CB 3.49Å; I539-F543 WeakPolarHBondContact O-CD2 3.3Å; I539-F543 VanDerWaalsContact O-CE2 3.31Å; I539-F543 WeakPolarHBondContact O-CE2 3.03Å; C540-F543 PolarHBondContact O-N 3.25Å; L541-F543 VanDerWaalsContact C-N 3.3Å; L541-F543 PolarHBondContact O-N 3.03Å; F543-Y547 VanDerWaalsContact O-CB 3.3Å; F543-Y547 WeakPolarHBondContact O-CB 3.49Å; F543-Y547 PolarHBondContact O-N 2.86Å
544	G	90.4	Very high	88.5	Confident	4 Å²	4	14.9 Å²	14.9	4%	0.041	8%	0.083	C	C	.	.	H	α-helix	trans	-69.3	-40.5	173.4	0	0	0	0	0	113.9	Q379 C540 L541 P542 Y547 R548	Q379-G544 VanDerWaalsContact CG-CA 3.45Å; C540-G544 PolarHBondContact O-N 3.13Å; L541-G544 WeakPolarHBondContact O-CA 3.41Å; L541-G544 PolarHBondContact O-N 3.25Å; P542-G544 PolarHBondContact O-N 2.96Å; G544-Y547 WeakPolarHBondContact O-CB 3.49Å; G544-Y547 PolarHBondContact O-N 2.9Å; G544-R548 WeakPolarHBondContact O-CG 3.11Å; G544-R548 PolarHBondContact O-N 3.17Å
545	I	89	Confident	88.7	Confident	4 Å²	4	14.9 Å²	14.9	2%	0.021	8%	0.083	C	C	.	.	H	α-helix	trans	-62.7	-48.2	175.4	-63.2	171.9	0	0	0	109.4	E249 W508 P511 A512 L541 P542 Y547 R548 M549	E249-I545 VanDerWaalsContact CD-CG2 3.43Å; E249-I545 HydrophobicContact CG-CG2 3.97Å; E249-I545 VanDerWaalsContact OE1-CB 3.28Å; E249-I545 WeakPolarHBondContact OE1-CB 3.48Å; E249-I545 WeakPolarHBondContact OE1-CG2 3.18Å; W508-I545 VanDerWaalsContact NE1-CG2 3.27Å; P511-I545 HydrophobicContact CB-CD1 4.3Å; P511-I545 HydrophobicContact CB-CG1 4.08Å; P511-I545 HydrophobicContact CG-CG1 4.08Å; A512-I545 HydrophobicContact CB-CG2 4.31Å; L541-I545 HydrophobicContact CG-CD1 4.4Å; L541-I545 PolarHBondContact O-N 3.44Å; P542-I545 PolarHBondContact O-N 2.85Å; P542-I545 VanDerWaalsContact O-N 3.16Å; I545-Y547 VanDerWaalsContact C-N 3.33Å; I545-Y547 PolarHBondContact O-N 3.4Å; I545-R548 PolarHBondContact O-N 3.1Å; I545-M549 PolarHBondContact O-N 3.16Å; I545-M549 VanDerWaalsContact O-N 3.15Å
546	F	88.3	Confident	88.7	Confident	11 Å²	11	17.1 Å²	17.1	5%	0.048	9%	0.09	C	C	.	.	H	α-helix	trans	-57.9	-43.2	173.9	-178.5	-97	0	0	0	112.2	F253 T256 A375 P542 R548 M549 H550	F253-F546 HydrophobicContact CD1-CE2 4.44Å; F253-F546 AromaticContact CD2-CD2 3.79Å; F253-F546 HydrophobicContact CD2-CD2 3.79Å; F253-F546 HydrophobicContact CD2-CE2 4.12Å; F253-F546 HydrophobicContact CE1-CE2 4.42Å; F253-F546 AromaticContact CE2-CD2 3.58Å; F253-F546 HydrophobicContact CE2-CD2 3.58Å; F253-F546 HydrophobicContact CE2-CE2 4.1Å; F253-F546 HydrophobicContact CG-CD2 4.41Å; F253-F546 HydrophobicContact CG-CE2 4.29Å; F253-F546 HydrophobicContact CZ-CD2 4.05Å; F253-F546 HydrophobicContact CZ-CE2 4.25Å; T256-F546 HydrophobicContact CG2-CZ 4.14Å; A375-F546 HydrophobicContact CB-CD1 3.73Å; A375-F546 HydrophobicContact CB-CE1 4.33Å; P542-F546 WeakPolarHBondContact O-CB 3.47Å; P542-F546 PolarHBondContact O-N 3.04Å; F546-R548 PolarHBondContact O-N 3.1Å; F546-M549 PolarHBondContact O-N 3.25Å; F546-H550 WeakPolarHBondContact O-CB 3.31Å; F546-H550 PolarHBondContact O-N 3.03Å
547	Y	92.4	Very high	88.3	Confident	0 Å²	0	20.1 Å²	20.1	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-55.7	-50.3	175.6	173.9	-93	0	0	0	111.8	L372 A375 A376 H414 N418 F543 G544 I545 M549 H550 A551	L372-Y547 HydrophobicContact CD1-CD2 3.83Å; L372-Y547 HydrophobicContact CD1-CE2 3.43Å; L372-Y547 VanDerWaalsContact CD1-CE2 3.43Å; L372-Y547 HydrophobicContact CG-CD2 4.41Å; L372-Y547 HydrophobicContact CG-CE2 3.85Å; L372-Y547 WeakPolarHBondContact O-CD2 2.87Å; A375-Y547 HydrophobicContact CB-CD2 4.21Å; A376-Y547 HydrophobicContact CB-CD2 3.99Å; A376-Y547 HydrophobicContact CB-CE2 4.01Å; H414-Y547 AromaticContact CD2-CD1 3.42Å; H414-Y547 VanDerWaalsContact CD2-CD1 3.42Å; H414-Y547 WeakPolarHBondContact CD2-CD1 3.5Å; H414-Y547 AromaticContact CD2-CE1 3.19Å; H414-Y547 WeakPolarHBondContact CD2-CE1 3.22Å; H414-Y547 AromaticContact CD2-CG 3.98Å; H414-Y547 AromaticContact CD2-CZ 3.54Å; H414-Y547 AromaticContact NE2-CD1 3.47Å; H414-Y547 WeakPolarHBondContact NE2-CD1 3.43Å; H414-Y547 AromaticContact NE2-CE1 3.57Å; N418-Y547 WeakPolarHBondContact OD1-CE2 3.17Å; N418-Y547 VanDerWaalsContact OD1-CZ 3.26Å; N418-Y547 PolarHBondContact OD1-OH 2.8Å; F543-Y547 VanDerWaalsContact O-CB 3.3Å; F543-Y547 WeakPolarHBondContact O-CB 3.49Å; F543-Y547 PolarHBondContact O-N 2.86Å; G544-Y547 WeakPolarHBondContact O-CB 3.49Å; G544-Y547 PolarHBondContact O-N 2.9Å; I545-Y547 VanDerWaalsContact C-N 3.33Å; I545-Y547 PolarHBondContact O-N 3.4Å; Y547-M549 PolarHBondContact O-N 3.43Å; Y547-H550 PolarHBondContact O-N 3.45Å; Y547-A551 HydrophobicContact CE1-CB 4.33Å; Y547-A551 VanDerWaalsContact O-CB 3.3Å; Y547-A551 WeakPolarHBondContact O-CB 3.26Å; Y547-A551 PolarHBondContact O-N 2.9Å
548	R	93	Very high	88	Confident	10 Å²	10	20.2 Å²	20.2	4%	0.038	10%	0.104	C	C	.	.	H	α-helix	trans	-62	-43.4	-177.9	-64.8	-65.6	-178	-161.9	-2	111.5	Q413 H414 N504 W508 G544 I545 F546 A551 V552	Q413-R548 VanDerWaalsContact OE1-CZ 3.25Å; H414-R548 PolarHBondContact CE1-NH2 2.92Å; N504-R548 VanDerWaalsContact OD1-CD 3.28Å; N504-R548 WeakPolarHBondContact OD1-CD 3.48Å; N504-R548 PolarHBondContact OD1-NH1 2.73Å; N504-R548 VanDerWaalsContact OD1-NH1 3.14Å; W508-R548 HydrophobicContact CB-CB 3.72Å; W508-R548 HydrophobicContact CB-CG 4.48Å; W508-R548 HydrophobicContact CG-CB 4.36Å; G544-R548 WeakPolarHBondContact O-CG 3.11Å; G544-R548 PolarHBondContact O-N 3.17Å; I545-R548 PolarHBondContact O-N 3.1Å; F546-R548 PolarHBondContact O-N 3.1Å; R548-A551 PolarHBondContact O-N 3.35Å; R548-V552 WeakPolarHBondContact O-CG2 3.45Å; R548-V552 PolarHBondContact O-N 3.36Å
549	M	86.1	Confident	87.8	Confident	27 Å²	27	20.7 Å²	20.7	13%	0.133	11%	0.106	C	C	.	.	H	α-helix	trans	-60.7	-47.2	174.8	-78.2	-67.4	-79.4	0	0	112.1	W102 F253 W508 I545 F546 Y547 A551 V552 S553	W102-M549 VanDerWaalsContact CZ3-O 3.31Å; W102-M549 WeakPolarHBondContact CZ3-O 3.42Å; F253-M549 HydrophobicContact CZ-CB 3.93Å; F253-M549 HydrophobicContact CZ-CE 4.34Å; F253-M549 HydrophobicContact CZ-CG 4.27Å; W508-M549 VanDerWaalsContact CD1-CG 3.4Å; W508-M549 HydrophobicContact CD2-CG 3.98Å; W508-M549 HydrophobicContact CD2-SD 3.54Å; W508-M549 VanDerWaalsContact CD2-SD 3.54Å; W508-M549 HydrophobicContact CE3-SD 4.02Å; W508-M549 HydrophobicContact CG-CG 3.91Å; W508-M549 HydrophobicContact CG-SD 3.98Å; W508-M549 HydrophobicContact CH2-SD 4.18Å; W508-M549 HydrophobicContact CZ2-CE 4.23Å; W508-M549 HydrophobicContact CZ2-CG 4.21Å; W508-M549 HydrophobicContact CZ2-SD 3.72Å; W508-M549 HydrophobicContact CZ3-SD 4.32Å; I545-M549 PolarHBondContact O-N 3.16Å; I545-M549 VanDerWaalsContact O-N 3.15Å; F546-M549 PolarHBondContact O-N 3.25Å; Y547-M549 PolarHBondContact O-N 3.43Å; M549-A551 VanDerWaalsContact C-N 3.32Å; M549-A551 PolarHBondContact O-N 3.04Å; M549-V552 PolarHBondContact O-N 2.98Å; M549-S553 PolarHBondContact O-N 2.78Å
550	H	86.4	Confident	87.3	Confident	12 Å²	12	20.8 Å²	20.8	6%	0.056	11%	0.109	C	C	.	.	H	α-helix	trans	-61.6	-43.7	179.1	-170	-79.3	0	0	0	111.3	F546 Y547 V552 S553 S554	F546-H550 WeakPolarHBondContact O-CB 3.31Å; F546-H550 PolarHBondContact O-N 3.03Å; Y547-H550 PolarHBondContact O-N 3.45Å; H550-V552 PolarHBondContact O-N 3.13Å; H550-S553 PolarHBondContact O-N 3.08Å; H550-S554 PolarHBondContact ND1-OG 3.12Å; H550-S554 PolarHBondContact O-N 3.27Å; H550-S554 PolarHBondContact O-OG 2.77Å; H550-S554 VanDerWaalsContact O-OG 3.13Å
551	A	91.1	Very high	86.3	Confident	0 Å²	0	24 Å²	24	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-62.2	-41.7	177.2	0	0	0	0	0	112.6	I421 Y547 R548 M549 S553 S554 L555	I421-A551 HydrophobicContact CD1-CB 3.93Å; Y547-A551 HydrophobicContact CE1-CB 4.33Å; Y547-A551 VanDerWaalsContact O-CB 3.3Å; Y547-A551 WeakPolarHBondContact O-CB 3.26Å; Y547-A551 PolarHBondContact O-N 2.9Å; R548-A551 PolarHBondContact O-N 3.35Å; M549-A551 VanDerWaalsContact C-N 3.32Å; M549-A551 PolarHBondContact O-N 3.04Å; A551-S553 VanDerWaalsContact C-N 3.27Å; A551-S553 PolarHBondContact O-N 3.45Å; A551-S554 PolarHBondContact O-N 2.92Å; A551-L555 WeakPolarHBondContact O-CB 3.13Å; A551-L555 WeakPolarHBondContact O-CD1 3.28Å; A551-L555 WeakPolarHBondContact O-CG 3.31Å; A551-L555 PolarHBondContact O-N 2.95Å
552	V	90.3	Very high	85.2	Confident	27 Å²	27	24 Å²	24	16%	0.164	13%	0.125	C	C	.	.	H	α-helix	trans	-53.5	-45.8	175.2	163.1	0	0	0	0	110.9	L501 N504 V505 R548 M549 H550 L556	L501-V552 HydrophobicContact CG-CG1 4.16Å; N504-V552 HydrophobicContact CB-CG2 3.58Å; V505-V552 HydrophobicContact CG2-CG1 4.09Å; V505-V552 HydrophobicContact CG2-CG2 3.72Å; R548-V552 WeakPolarHBondContact O-CG2 3.45Å; R548-V552 PolarHBondContact O-N 3.36Å; M549-V552 PolarHBondContact O-N 2.98Å; H550-V552 PolarHBondContact O-N 3.13Å; V552-L556 PolarHBondContact O-N 3.47Å
553	S	82.8	Confident	85.1	Confident	8 Å²	8	24.8 Å²	24.8	6%	0.056	13%	0.129	C	C	.	.	H	α-helix	trans	-75.7	-39.7	178.6	-178.1	0	0	0	0	114.1	W102 M549 H550 A551 L555 L556 E557	W102-S553 VanDerWaalsContact CD2-OG 3.24Å; W102-S553 WeakPolarHBondContact CZ2-OG 3.45Å; W102-S553 PolarHBondContact NE1-OG 3.32Å; M549-S553 PolarHBondContact O-N 2.78Å; H550-S553 PolarHBondContact O-N 3.08Å; A551-S553 VanDerWaalsContact C-N 3.27Å; A551-S553 PolarHBondContact O-N 3.45Å; S553-L555 PolarHBondContact O-N 3.22Å; S553-L556 WeakPolarHBondContact O-CB 3.37Å; S553-L556 PolarHBondContact O-N 3.33Å; S553-L556 VanDerWaalsContact O-N 3.09Å; S553-E557 PolarHBondContact O-N 2.92Å
554	S	86	Confident	84.8	Confident	5 Å²	5	23 Å²	23	4%	0.035	12%	0.122	C	C	.	.	H	α-helix	trans	-58.1	-38.1	176.2	-59.4	0	0	0	0	109.8	I421 H550 A551 E557 V558	I421-S554 VanDerWaalsContact CG2-CB 3.48Å; H550-S554 PolarHBondContact ND1-OG 3.12Å; H550-S554 PolarHBondContact O-N 3.27Å; H550-S554 PolarHBondContact O-OG 2.77Å; H550-S554 VanDerWaalsContact O-OG 3.13Å; A551-S554 PolarHBondContact O-N 2.92Å; S554-E557 PolarHBondContact O-N 2.81Å; S554-V558 WeakPolarHBondContact O-CG2 3.33Å; S554-V558 PolarHBondContact O-N 3.48Å
555	L	89.5	Confident	84.5	Confident	0 Å²	0	24.1 Å²	24.1	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-68.1	-36.9	174	-70.4	168	0	0	0	113.2	F420 I421 L500 L501 A551 S553 V558 Y559	F420-L555 HydrophobicContact CD1-CD2 4.11Å; F420-L555 HydrophobicContact CE1-CD2 3.73Å; I421-L555 HydrophobicContact CD1-CD2 4.42Å; I421-L555 HydrophobicContact CD1-CG 4.2Å; I421-L555 HydrophobicContact CG1-CD2 4.05Å; I421-L555 HydrophobicContact CG1-CG 4.31Å; L500-L555 HydrophobicContact CB-CD1 3.59Å; L500-L555 HydrophobicContact CB-CD2 4.04Å; L500-L555 HydrophobicContact CB-CG 4.45Å; L500-L555 HydrophobicContact CD1-CD2 4.02Å; L501-L555 HydrophobicContact CB-CB 4.38Å; A551-L555 WeakPolarHBondContact O-CB 3.13Å; A551-L555 WeakPolarHBondContact O-CD1 3.28Å; A551-L555 WeakPolarHBondContact O-CG 3.31Å; A551-L555 PolarHBondContact O-N 2.95Å; S553-L555 PolarHBondContact O-N 3.22Å; L555-V558 PolarHBondContact O-N 2.72Å; L555-Y559 WeakPolarHBondContact O-CB 3.46Å; L555-Y559 PolarHBondContact O-N 3.41Å
556	L	85.4	Confident	84.2	Confident	81 Å²	81	25.2 Å²	25.2	42%	0.424	13%	0.133	S	C	.	.	H	α-helix	trans	-63.2	-42.5	173.3	-177.1	64.3	0	0	0	111.5	L501 V552 S553 Y559 V560	L501-L556 HydrophobicContact CD1-CB 3.9Å; L501-L556 HydrophobicContact CD1-CD1 4.09Å; V552-L556 PolarHBondContact O-N 3.47Å; S553-L556 WeakPolarHBondContact O-CB 3.37Å; S553-L556 PolarHBondContact O-N 3.33Å; S553-L556 VanDerWaalsContact O-N 3.09Å; L556-Y559 WeakPolarHBondContact O-CB 3.13Å; L556-Y559 PolarHBondContact O-N 3.44Å; L556-V560 WeakPolarHBondContact O-CG2 3.42Å; L556-V560 PolarHBondContact O-N 3.13Å
557	E	82	Confident	84	Confident	79 Å²	79	26.1 Å²	26.1	37%	0.369	14%	0.138	S	C	.	.	H	α-helix	trans	-63	-43.6	174.8	-174.8	174.4	-178.1	0	0	110.9	L425 S553 S554 Y559 V560 L561	L425-E557 HydrophobicContact CD2-CB 4.44Å; L425-E557 HydrophobicContact CD2-CG 4.17Å; S553-E557 PolarHBondContact O-N 2.92Å; S554-E557 PolarHBondContact O-N 2.81Å; E557-Y559 VanDerWaalsContact C-N 3.31Å; E557-Y559 PolarHBondContact O-N 2.93Å; E557-V560 PolarHBondContact O-N 3.12Å; E557-L561 HydrophobicContact CG-CD1 3.8Å; E557-L561 HydrophobicContact CG-CG 4.36Å; E557-L561 WeakPolarHBondContact O-CB 3.41Å; E557-L561 VanDerWaalsContact O-CG 3.28Å; E557-L561 WeakPolarHBondContact O-CG 3.14Å; E557-L561 PolarHBondContact O-N 3.26Å
558	V	82.3	Confident	83.4	Confident	2 Å²	2	27.9 Å²	27.9	1%	0.012	15%	0.147	C	C	.	.	H	α-helix	trans	-60.9	-39	174.3	170.6	0	0	0	0	112	L425 A497 S554 L555 L561 S562	L425-V558 HydrophobicContact CD2-CG2 4.12Å; L425-V558 HydrophobicContact CG-CG2 4.38Å; A497-V558 HydrophobicContact CB-CG1 4.38Å; S554-V558 WeakPolarHBondContact O-CG2 3.33Å; S554-V558 PolarHBondContact O-N 3.48Å; L555-V558 PolarHBondContact O-N 2.72Å; V558-L561 PolarHBondContact O-N 3.09Å; V558-S562 VanDerWaalsContact O-CB 3.24Å; V558-S562 WeakPolarHBondContact O-CB 3.3Å; V558-S562 PolarHBondContact O-N 2.95Å; V558-S562 PolarHBondContact O-OG 3.16Å
559	Y	83.3	Confident	82.7	Confident	11 Å²	11	29.1 Å²	29.1	4%	0.043	16%	0.155	C	C	.	.	H	α-helix	trans	-62.8	-41.3	175	170.5	-102.3	0	0	0	112.2	L284 R494 L498 L555 L556 E557	L284-Y559 HydrophobicContact CB-CE1 4.31Å; L284-Y559 HydrophobicContact CD2-CE1 4.3Å; L284-Y559 PolarHBondContact O-OH 2.93Å; L284-Y559 VanDerWaalsContact O-OH 3.12Å; R494-Y559 HydrophobicContact CB-CD2 3.83Å; R494-Y559 HydrophobicContact CB-CE2 3.83Å; R494-Y559 HydrophobicContact CG-CD2 3.89Å; R494-Y559 HydrophobicContact CG-CE2 3.98Å; L498-Y559 HydrophobicContact CD1-CD2 3.93Å; L498-Y559 HydrophobicContact CD1-CE2 3.41Å; L498-Y559 VanDerWaalsContact CD1-CE2 3.41Å; L498-Y559 HydrophobicContact CD2-CD1 4.29Å; L498-Y559 HydrophobicContact CD2-CD2 3.86Å; L498-Y559 HydrophobicContact CD2-CE1 4.4Å; L498-Y559 HydrophobicContact CD2-CE2 3.99Å; L498-Y559 HydrophobicContact CD2-CG 4.01Å; L498-Y559 HydrophobicContact CG-CD2 3.57Å; L498-Y559 HydrophobicContact CG-CE2 3.62Å; L498-Y559 HydrophobicContact CG-CG 4.22Å; L555-Y559 WeakPolarHBondContact O-CB 3.46Å; L555-Y559 PolarHBondContact O-N 3.41Å; L556-Y559 WeakPolarHBondContact O-CB 3.13Å; L556-Y559 PolarHBondContact O-N 3.44Å; E557-Y559 VanDerWaalsContact C-N 3.31Å; E557-Y559 PolarHBondContact O-N 2.93Å
560	V	76.3	Confident	82.5	Confident	67 Å²	67	29.3 Å²	29.3	41%	0.406	16%	0.157	S	C	.	.	H	α-helix	trans	-71.1	-34.7	178.2	174.4	0	0	0	0	111.9	L556 E557	L556-V560 WeakPolarHBondContact O-CG2 3.42Å; L556-V560 PolarHBondContact O-N 3.13Å; E557-V560 PolarHBondContact O-N 3.12Å
561	L	69.4	Low	82.1	Confident	83 Å²	83	30.8 Å²	30.8	44%	0.435	17%	0.165	S	C	.	.	H	α-helix	trans	-81.3	-24.3	-179.6	-70.7	172.2	0	0	0	114.2	E557 V558	E557-L561 HydrophobicContact CG-CD1 3.8Å; E557-L561 HydrophobicContact CG-CG 4.36Å; E557-L561 WeakPolarHBondContact O-CB 3.41Å; E557-L561 VanDerWaalsContact O-CG 3.28Å; E557-L561 WeakPolarHBondContact O-CG 3.14Å; E557-L561 PolarHBondContact O-N 3.26Å; V558-L561 PolarHBondContact O-N 3.09Å
562	S	67.1	Low	81.3	Confident	6 Å²	6	33.5 Å²	33.5	4%	0.042	18%	0.181	C	C	.	.			trans	-75.7	0	178.1	-63.7	0	0	0	0	111.5	R490 R494 V558	R490-S562 WeakPolarHBondContact CD-O 3.47Å; R490-S562 WeakPolarHBondContact CG-O 3.47Å; R494-S562 PolarHBondContact NE-OXT 3.31Å; R494-S562 PolarHBondContact NH2-OXT 3.21Å; V558-S562 VanDerWaalsContact O-CB 3.24Å; V558-S562 WeakPolarHBondContact O-CB 3.3Å; V558-S562 PolarHBondContact O-N 2.95Å; V558-S562 PolarHBondContact O-OG 3.16Å

Retrieved 562 of 562 residues in 737.8 ms (Link to these results)

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