A0A096NTZ5_PAPAN Loading...

Inositol polyphosphate-5-phosphatase F

AlphaFold DB , UniProt , Accession A0A096NTZ5, Species PAPAN (Papio anubis, Olive baboon), Gene INPP5F, Length 1,133 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M91.9Very high91.5Very high32 Ų3226.5 Ų26.516%0.15813%0.125CC..  0144.30-55.7162.8-172.900109.3L12 Q13 Q14 L47 V48 F229 W230M1-L12 HydrophobicContact SD-CD2 4.12Å; M1-Q13 CarbonylContact C-O 3.6Å; M1-Q13 WeakPolarHBondContact CA-O 3.4Å; M1-Q14 HydrophobicContact CG-CB 4.16Å; M1-L47 WeakPolarHBondContact O-CA 3.19Å; M1-V48 HydrophobicContact CB-CG2 3.93Å; M1-V48 WeakPolarHBondContact CB-O 3.28Å; M1-V48 PolarHBondContact N-O 3.09Å; M1-V48 PolarHBondContact O-N 2.66Å; M1-F229 HydrophobicContact CE-CE1 4.39Å; M1-W230 HydrophobicContact CE-CE3 4.22Å; M1-W230 HydrophobicContact CE-CZ3 4.1Å; M1-W230 HydrophobicContact CG-CZ3 4.18Å; M1-W230 HydrophobicContact SD-CE3 4.11Å; M1-W230 HydrophobicContact SD-CZ3 3.57Å; M1-W230 VanDerWaalsContact SD-CZ3 3.57Å
2E93.6Very high91.7Very high20 Ų2024.3 Ų24.39%0.09312%0.115CC..EExtended strand (participates in β ladder)trans-92.3130.2170.7-64.4177.181.100108.5F4 L12 Q13 L47 C107 K109 H110E2-F4 HydrophobicContact CB-CE2 3.77Å; E2-F4 HydrophobicContact CB-CZ 4.25Å; E2-L12 CarbonylContact O-C 3.57Å; E2-L12 WeakPolarHBondContact O-CA 3.37Å; E2-Q13 PolarHBondContact N-O 2.81Å; E2-Q13 PolarHBondContact O-N 3.3Å; E2-L47 HydrophobicContact CG-CD2 3.77Å; E2-C107 PolarHBondContact OE1-SG 2.99Å; E2-K109 IonicContact OE1-NZ 2.7Å; E2-K109 WeakPolarHBondContact OE2-CE 3.45Å; E2-K109 IonicContact OE2-NZ 3.15Å; E2-K109 PolarHBondContact OE2-NZ 3.22Å; E2-H110 IonicContact OE1-CE1 2.7Å; E2-H110 PolarHBondContact OE1-CE1 3.17Å; E2-H110 IonicContact OE1-ND1 3.19Å; E2-H110 PolarHBondContact OE1-ND1 3.3Å
3L94.4Very high91.8Very high0 Ų024.8 Ų24.80%012%0.117CC..EExtended strand (participates in β ladder)trans-102.8129.6178.217867.7000109.7L12 L45 G46 V48 L67 L92 L104L3-L12 HydrophobicContact CD1-CD1 4.09Å; L3-L12 HydrophobicContact CD1-CG 3.98Å; L3-L45 HydrophobicContact CD2-CB 4.05Å; L3-L45 HydrophobicContact CD2-CD1 3.88Å; L3-L45 HydrophobicContact CG-CB 4.19Å; L3-L45 HydrophobicContact CG-CD1 4.13Å; L3-L45 PolarHBondContact O-N 3.09Å; L3-G46 PolarHBondContact N-O 3.42Å; L3-V48 HydrophobicContact CB-CG1 4.43Å; L3-V48 HydrophobicContact CB-CG2 4.43Å; L3-V48 HydrophobicContact CD2-CG1 4.3Å; L3-L67 HydrophobicContact CD1-CD1 4.06Å; L3-L67 HydrophobicContact CD2-CD1 4.08Å; L3-L92 HydrophobicContact CD1-CD1 4.33Å; L3-L92 HydrophobicContact CD2-CD1 4Å; L3-L104 HydrophobicContact CD2-CD1 3.78Å
4F92.4Very high91.7Very high6 Ų629.1 Ų29.13%0.02614%0.137CC..EExtended strand (participates in β ladder)trans-121.1152.1172.4-56.3-97.2000111.1E2 Y10 I11 Q13 L36 I43 C44 H110E2-F4 HydrophobicContact CB-CE2 3.77Å; E2-F4 HydrophobicContact CB-CZ 4.25Å; F4-Y10 CarbonylContact O-C 3.56Å; F4-Y10 WeakPolarHBondContact O-CA 3.35Å; F4-I11 HydrophobicContact CB-CB 4.36Å; F4-I11 PolarHBondContact N-O 3.31Å; F4-I11 PolarHBondContact O-N 3.27Å; F4-Q13 HydrophobicContact CE2-CB 4.05Å; F4-L36 HydrophobicContact CB-CD1 4.34Å; F4-L36 HydrophobicContact CD1-CD2 4.26Å; F4-L36 HydrophobicContact CD2-CD1 4.3Å; F4-L36 HydrophobicContact CD2-CD2 4.07Å; F4-L36 HydrophobicContact CE1-CD2 3.95Å; F4-L36 HydrophobicContact CE2-CD2 3.74Å; F4-L36 HydrophobicContact CG-CD1 4.16Å; F4-L36 HydrophobicContact CG-CD2 4.32Å; F4-L36 HydrophobicContact CZ-CD2 3.67Å; F4-I43 CarbonylContact C-O 3.59Å; F4-I43 WeakPolarHBondContact CA-O 3.35Å; F4-C44 HydrophobicContact CD1-CB 3.81Å; F4-C44 HydrophobicContact CE1-CB 3.75Å; F4-H110 AromaticContact CE1-CE1 3.8Å; F4-H110 AromaticContact CE1-ND1 3.9Å; F4-H110 AromaticContact CZ-CE1 3.52Å; F4-H110 AromaticContact CZ-ND1 3.87Å
5Q90.9Very high91.5Very high19 Ų1930.9 Ų30.99%0.08917%0.167CC..EExtended strand (participates in β ladder)trans-117.1120.3167.9176.5-174.2-15.700108.7Y10 P42 I43 L45 P99Q5-Y10 HydrophobicContact CB-CD1 3.93Å; Q5-Y10 HydrophobicContact CB-CE1 4.03Å; Q5-Y10 HydrophobicContact CG-CD1 4.09Å; Q5-Y10 HydrophobicContact CG-CE1 3.83Å; Q5-P42 WeakPolarHBondContact O-CA 3.26Å; Q5-I43 PolarHBondContact N-O 2.95Å; Q5-I43 PolarHBondContact O-N 2.93Å; Q5-L45 HydrophobicContact CB-CD1 3.79Å; Q5-L45 HydrophobicContact CB-CD2 4.34Å; Q5-L45 HydrophobicContact CB-CG 4.04Å; Q5-P99 VanDerWaalsContact OE1-CG 3.25Å
6A89.7Confident91.3Very high6 Ų639.8 Ų39.85%0.0521%0.207CC..  trans-102.3175.8165.700000109.7D8 H9 I11 R23 A39A6-D8 PolarHBondContact O-N 3.49Å; A6-H9 PolarHBondContact N-O 3.19Å; A6-I11 HydrophobicContact CB-CD1 4.28Å; A6-R23 PolarHBondContact O-NH1 3.3Å; A6-A39 HydrophobicContact CB-CB 3.98Å
7K85.4Confident91.3Very high123 Ų12343.4 Ų43.454%0.53522%0.217SC..SBendtrans-49.3-53.9177-175.1-173169.3-163.40112.8R23 W40K7-R23 PolarHBondContact O-NH1 3.19Å; K7-W40 HydrophobicContact CB-CB 4.31Å; K7-W40 PolarHBondContact N-O 2.87Å
8D88.1Confident91.4Very high43 Ų4341.1 Ų41.123%0.2321%0.206CC..SBendtrans-107.6-3.6-171.3-63.3-87.8000114.3A6 R23 R24A6-D8 PolarHBondContact O-N 3.49Å; D8-R23 WeakPolarHBondContact O-CB 3.42Å; D8-R23 PolarHBondContact O-N 3.38Å; D8-R24 IonicContact OD1-CZ 2.77Å; D8-R24 IonicContact OD1-NE 2.66Å; D8-R24 PolarHBondContact OD1-NE 2.79Å; D8-R24 IonicContact OD1-NH2 3.45Å; D8-R24 PolarHBondContact OD1-NH2 3.47Å
9H91.9Very high91.5Very high41 Ų4138.9 Ų38.919%0.1920%0.195CC..EExtended strand (participates in β ladder)trans-143148.6-173.7-65.184.5000112.6A6 I11 W20 C21A6-H9 PolarHBondContact N-O 3.19Å; H9-I11 HydrophobicContact CB-CG1 4.13Å; H9-W20 HydrophobicContact CB-CE3 4.02Å; H9-W20 AromaticContact CD2-CE3 3.9Å; H9-W20 AromaticContact CG-CE3 3.73Å; H9-C21 CarbonylContact C-O 3.55Å; H9-C21 VanDerWaalsContact CA-O 3.26Å; H9-C21 WeakPolarHBondContact CA-O 3.41Å
10Y93.4Very high91.6Very high1 Ų137.5 Ų37.50%0.00419%0.187CC..EExtended strand (participates in β ladder)trans-93.1140.9151.2-62.7-76.4000108.5F4 Q5 C21 R23 L45 L92 S93 L94F4-Y10 CarbonylContact O-C 3.56Å; F4-Y10 WeakPolarHBondContact O-CA 3.35Å; Q5-Y10 HydrophobicContact CB-CD1 3.93Å; Q5-Y10 HydrophobicContact CB-CE1 4.03Å; Q5-Y10 HydrophobicContact CG-CD1 4.09Å; Q5-Y10 HydrophobicContact CG-CE1 3.83Å; Y10-C21 PolarHBondContact N-O 2.85Å; Y10-C21 PolarHBondContact O-N 2.77Å; Y10-R23 HydrophobicContact CD2-CG 3.62Å; Y10-R23 HydrophobicContact CE2-CG 3.62Å; Y10-R23 HydrophobicContact CG-CG 4.35Å; Y10-L45 HydrophobicContact CD1-CD1 4.24Å; Y10-L45 HydrophobicContact CE1-CD1 4.17Å; Y10-L92 HydrophobicContact CD1-CD1 4.09Å; Y10-L92 HydrophobicContact CD2-CD1 4.41Å; Y10-L92 HydrophobicContact CE1-CD1 4.29Å; Y10-L92 HydrophobicContact CE2-CB 4.07Å; Y10-L92 HydrophobicContact CG-CD1 4.14Å; Y10-S93 WeakPolarHBondContact CE2-O 3.47Å; Y10-S93 PolarHBondContact OH-O 3.19Å; Y10-S93 VanDerWaalsContact OH-O 3.05Å; Y10-L94 HydrophobicContact CD2-CD2 3.45Å; Y10-L94 VanDerWaalsContact CD2-CD2 3.45Å; Y10-L94 HydrophobicContact CE2-CD2 3.57Å
11I94.4Very high91.7Very high0 Ų035.7 Ų35.70%018%0.178CC..EExtended strand (participates in β ladder)trans-128.9121.8-174.6-52.8167000108.2F4 A6 H9 A18 L19 W20 L36 A39F4-I11 HydrophobicContact CB-CB 4.36Å; F4-I11 PolarHBondContact N-O 3.31Å; F4-I11 PolarHBondContact O-N 3.27Å; A6-I11 HydrophobicContact CB-CD1 4.28Å; H9-I11 HydrophobicContact CB-CG1 4.13Å; I11-A18 HydrophobicContact CG2-CB 4.12Å; I11-L19 WeakPolarHBondContact CA-O 3.29Å; I11-W20 HydrophobicContact CD1-CD2 3.92Å; I11-W20 HydrophobicContact CD1-CE3 3.85Å; I11-W20 HydrophobicContact CD1-CH2 3.66Å; I11-W20 HydrophobicContact CD1-CZ2 3.7Å; I11-W20 HydrophobicContact CD1-CZ3 3.73Å; I11-W20 HydrophobicContact CG1-CD2 3.79Å; I11-W20 HydrophobicContact CG1-CE3 3.95Å; I11-W20 HydrophobicContact CG1-CG 4.19Å; I11-W20 HydrophobicContact CG1-CZ2 4.42Å; I11-W20 HydrophobicContact CG1-CZ3 4.34Å; I11-W20 HydrophobicContact CG2-CD2 4.34Å; I11-W20 HydrophobicContact CG2-CG 4.29Å; I11-L36 HydrophobicContact CD1-CD1 3.67Å; I11-L36 HydrophobicContact CG2-CD1 4.34Å; I11-A39 HydrophobicContact CD1-CB 3.8Å
12L94.6Very high91.6Very high1 Ų134.8 Ų34.81%0.00518%0.175CC..EExtended strand (participates in β ladder)trans-99.9124171.3-68.688.9000108.9M1 E2 L3 A18 L19 V48 V51 L65 L67 W230M1-L12 HydrophobicContact SD-CD2 4.12Å; E2-L12 CarbonylContact O-C 3.57Å; E2-L12 WeakPolarHBondContact O-CA 3.37Å; L3-L12 HydrophobicContact CD1-CD1 4.09Å; L3-L12 HydrophobicContact CD1-CG 3.98Å; L12-A18 CarbonylContact O-C 3.57Å; L12-A18 VanDerWaalsContact O-CA 3.26Å; L12-A18 WeakPolarHBondContact O-CA 3.31Å; L12-L19 HydrophobicContact CB-CB 4.5Å; L12-L19 PolarHBondContact N-O 3.22Å; L12-L19 PolarHBondContact O-N 3.28Å; L12-V48 HydrophobicContact CD2-CG2 3.78Å; L12-V51 HydrophobicContact CD2-CG2 3.79Å; L12-L65 HydrophobicContact CD1-CD2 4.29Å; L12-L67 HydrophobicContact CD1-CD2 4.45Å; L12-L67 HydrophobicContact CD2-CD1 4.24Å; L12-L67 HydrophobicContact CD2-CD2 3.85Å; L12-W230 HydrophobicContact CB-CH2 3.88Å; L12-W230 HydrophobicContact CB-CZ3 3.65Å; L12-W230 HydrophobicContact CD2-CZ3 4.31Å; L12-W230 VanDerWaalsContact O-CH2 3.26Å; L12-W230 WeakPolarHBondContact O-CH2 3.44Å
13Q92.9Very high91.4Very high30 Ų3034.4 Ų34.414%0.1417%0.173CC..EExtended strand (participates in β ladder)trans-111.8139.1177-171.2-173.8-10.300111.1M1 E2 F4 G15 A33M1-Q13 CarbonylContact C-O 3.6Å; M1-Q13 WeakPolarHBondContact CA-O 3.4Å; E2-Q13 PolarHBondContact N-O 2.81Å; E2-Q13 PolarHBondContact O-N 3.3Å; F4-Q13 HydrophobicContact CE2-CB 4.05Å; Q13-G15 PolarHBondContact NE2-O 3.39Å; Q13-A33 HydrophobicContact CG-CB 3.98Å
14Q90.5Very high90.8Very high85 Ų8541.3 Ų41.340%0.39720%0.199SC..EExtended strand (participates in β ladder)trans-146.8113.2162.4-177.1151-25.300110.7M1 E16 R17 F229M1-Q14 HydrophobicContact CG-CB 4.16Å; Q14-E16 PolarHBondContact O-N 2.81Å; Q14-R17 PolarHBondContact N-O 2.94Å; Q14-R17 PolarHBondContact O-N 2.93Å; Q14-F229 HydrophobicContact CB-CE1 4.08Å; Q14-F229 HydrophobicContact CB-CZ 4.39Å; Q14-F229 HydrophobicContact CG-CE1 4.2Å; Q14-F229 HydrophobicContact CG-CZ 3.98Å
15G88Confident90.3Very high57 Ų5746 Ų4659%0.58822%0.224SC*.THydrogen-bonded Turntrans61.5-127.5-17100000110.8Q13 A33Q13-G15 PolarHBondContact NE2-O 3.39Å; G15-A33 WeakPolarHBondContact O-CB 3.46Å
16E88.4Confident89.9Confident173 Ų17345 Ų4581%0.80822%0.22SC*.THydrogen-bonded Turntrans-85.4-7.3-179-59.5179.1150.600113.6Q14 A33Q14-E16 PolarHBondContact O-N 2.81Å; E16-A33 WeakPolarHBondContact O-CB 3.25Å; E16-A33 PolarHBondContact O-N 2.73Å
17R91Very high89.8Confident101 Ų10146 Ų4638%0.38123%0.23SC..EExtended strand (participates in β ladder)trans-97136.3-179.8-66.1178.9173.8132.91111.4Q14 D226 W230Q14-R17 PolarHBondContact N-O 2.94Å; Q14-R17 PolarHBondContact O-N 2.93Å; R17-D226 IonicContact CZ-OD1 3.35Å; R17-D226 IonicContact NE-OD1 2.67Å; R17-D226 PolarHBondContact NE-OD1 2.84Å; R17-D226 IonicContact NH2-OD1 2.96Å; R17-D226 PolarHBondContact NH2-OD1 2.92Å; R17-W230 HydrophobicContact CB-CZ2 4.12Å
18A93.5Very high90.1Very high1 Ų140.8 Ų40.81%0.00821%0.208CC..EExtended strand (participates in β ladder)trans-126.7135.6168.300000112I11 L12 R31I11-A18 HydrophobicContact CG2-CB 4.12Å; L12-A18 CarbonylContact O-C 3.57Å; L12-A18 VanDerWaalsContact O-CA 3.26Å; L12-A18 WeakPolarHBondContact O-CA 3.31Å; A18-R31 PolarHBondContact N-O 2.66Å; A18-R31 PolarHBondContact O-N 3.27Å
19L94.1Very high90.2Very high1 Ų143.1 Ų43.11%0.00522%0.217CC..EExtended strand (participates in β ladder)trans-106.5117169.917967.5000108.8I11 L12 L28 L30 V51 L219 W230I11-L19 WeakPolarHBondContact CA-O 3.29Å; L12-L19 HydrophobicContact CB-CB 4.5Å; L12-L19 PolarHBondContact N-O 3.22Å; L12-L19 PolarHBondContact O-N 3.28Å; L19-L28 HydrophobicContact CD1-CB 4.42Å; L19-L28 HydrophobicContact CD1-CD2 4.12Å; L19-L28 HydrophobicContact CD2-CD2 4.2Å; L19-L28 HydrophobicContact CG-CD2 4.09Å; L19-L30 HydrophobicContact CB-CD2 4.47Å; L19-L30 HydrophobicContact CD1-CD2 3.85Å; L19-V51 HydrophobicContact CD2-CG2 4Å; L19-L219 HydrophobicContact CD1-CD2 3.75Å; L19-L219 HydrophobicContact CD2-CD2 4.2Å; L19-W230 HydrophobicContact CB-CD2 3.81Å; L19-W230 HydrophobicContact CB-CE3 3.94Å; L19-W230 HydrophobicContact CB-CG 4.44Å; L19-W230 HydrophobicContact CB-CH2 4Å; L19-W230 HydrophobicContact CB-CZ2 3.85Å; L19-W230 HydrophobicContact CB-CZ3 4.03Å; L19-W230 HydrophobicContact CD2-CB 4.31Å; L19-W230 HydrophobicContact CD2-CD2 3.97Å; L19-W230 HydrophobicContact CD2-CE3 3.85Å; L19-W230 HydrophobicContact CD2-CG 4.18Å; L19-W230 HydrophobicContact CG-CD2 4.46Å
20W93.3Very high90.1Very high9 Ų943.4 Ų43.43%0.03422%0.22CC..EExtended strand (participates in β ladder)trans-98.9127.2-179.6-69.458.3000109.2H9 I11 L28 Q29 R31 D35 A39H9-W20 HydrophobicContact CB-CE3 4.02Å; H9-W20 AromaticContact CD2-CE3 3.9Å; H9-W20 AromaticContact CG-CE3 3.73Å; I11-W20 HydrophobicContact CD1-CD2 3.92Å; I11-W20 HydrophobicContact CD1-CE3 3.85Å; I11-W20 HydrophobicContact CD1-CH2 3.66Å; I11-W20 HydrophobicContact CD1-CZ2 3.7Å; I11-W20 HydrophobicContact CD1-CZ3 3.73Å; I11-W20 HydrophobicContact CG1-CD2 3.79Å; I11-W20 HydrophobicContact CG1-CE3 3.95Å; I11-W20 HydrophobicContact CG1-CG 4.19Å; I11-W20 HydrophobicContact CG1-CZ2 4.42Å; I11-W20 HydrophobicContact CG1-CZ3 4.34Å; I11-W20 HydrophobicContact CG2-CD2 4.34Å; I11-W20 HydrophobicContact CG2-CG 4.29Å; W20-L28 CarbonylContact O-C 3.53Å; W20-L28 WeakPolarHBondContact O-CA 3.36Å; W20-Q29 HydrophobicContact CB-CB 4.44Å; W20-Q29 PolarHBondContact N-O 3.26Å; W20-Q29 PolarHBondContact O-N 2.7Å; W20-R31 HydrophobicContact CG-CG 4.31Å; W20-D35 WeakPolarHBondContact CH2-O 3.46Å; W20-D35 HydrophobicContact CZ2-CB 3.86Å; W20-D35 VanDerWaalsContact CZ2-O 3.31Å; W20-D35 WeakPolarHBondContact CZ2-O 3.26Å; W20-A39 HydrophobicContact CH2-CB 3.82Å; W20-A39 HydrophobicContact CZ3-CB 4.35Å
21C93.1Very high89.9Confident0 Ų047.3 Ų47.30%024%0.235CC..EExtended strand (participates in β ladder)trans-117.7116.7175.9-171.50000109.2H9 Y10 G27 L28 L65 L94H9-C21 CarbonylContact C-O 3.55Å; H9-C21 VanDerWaalsContact CA-O 3.26Å; H9-C21 WeakPolarHBondContact CA-O 3.41Å; Y10-C21 PolarHBondContact N-O 2.85Å; Y10-C21 PolarHBondContact O-N 2.77Å; C21-G27 WeakPolarHBondContact CA-O 3.39Å; C21-L28 HydrophobicContact CB-CD2 3.56Å; C21-L65 HydrophobicContact CB-CD2 3.94Å; C21-L94 VanDerWaalsContact SG-CD1 3.55Å
22S90.3Very high89.7Confident13 Ų1350.7 Ų50.79%0.09126%0.257CS..EExtended strand (participates in β ladder)trans-65.6133.2-179.6157.30000111.8R24 D25 G26 G27S22-R24 PolarHBondContact O-N 3.31Å; S22-R24 PolarHBondContact OG-N 3.1Å; S22-D25 WeakPolarHBondContact CB-OD1 3.39Å; S22-D25 PolarHBondContact OG-N 3.45Å; S22-D25 PolarHBondContact OG-OD1 3.11Å; S22-G26 WeakPolarHBondContact O-CA 3.35Å; S22-G26 PolarHBondContact O-N 3.08Å; S22-G27 PolarHBondContact N-O 2.92Å
23R88.7Confident89.3Confident12 Ų1251.5 Ų51.55%0.04526%0.263CS..THydrogen-bonded Turntrans-825.4175.5-67.4175.764.4-158.9-2.2113.2A6 K7 D8 Y10 L94 S95 E96 M97A6-R23 PolarHBondContact O-NH1 3.3Å; K7-R23 PolarHBondContact O-NH1 3.19Å; D8-R23 WeakPolarHBondContact O-CB 3.42Å; D8-R23 PolarHBondContact O-N 3.38Å; Y10-R23 HydrophobicContact CD2-CG 3.62Å; Y10-R23 HydrophobicContact CE2-CG 3.62Å; Y10-R23 HydrophobicContact CG-CG 4.35Å; R23-L94 CarbonylContact O-C 3.57Å; R23-L94 VanDerWaalsContact O-C 3.25Å; R23-S95 VanDerWaalsContact CZ-O 3.32Å; R23-S95 PolarHBondContact NE-O 3.27Å; R23-S95 PolarHBondContact NH2-O 3.49Å; R23-S95 WeakPolarHBondContact O-CA 3.45Å; R23-S95 PolarHBondContact O-N 3.42Å; R23-E96 PolarHBondContact NH2-O 3.14Å; R23-M97 PolarHBondContact NH2-O 2.93Å
24R82.1Confident89.2Confident145 Ų14554.7 Ų54.755%0.54729%0.285SS..THydrogen-bonded Turntrans-108.7-51-177.8-63.8-175.7176.4-71.3-13.1113D8 S22 E96D8-R24 IonicContact OD1-CZ 2.77Å; D8-R24 IonicContact OD1-NE 2.66Å; D8-R24 PolarHBondContact OD1-NE 2.79Å; D8-R24 IonicContact OD1-NH2 3.45Å; D8-R24 PolarHBondContact OD1-NH2 3.47Å; S22-R24 PolarHBondContact O-N 3.31Å; S22-R24 PolarHBondContact OG-N 3.1Å; R24-E96 IonicContact CZ-OE1 3.56Å; R24-E96 IonicContact NH1-OE1 3.68Å; R24-E96 PolarHBondContact NH1-OE1 3.36Å; R24-E96 IonicContact NH2-OE1 3.94Å; R24-E96 PolarHBondContact NH2-OE1 3.35Å
25D81.5Confident89.1Confident104 Ų10452.2 Ų52.256%0.55628%0.275SS*.THydrogen-bonded Turntrans-119.5-10.2-174.455.816.3000113.4S22 G27S22-D25 WeakPolarHBondContact CB-OD1 3.39Å; S22-D25 PolarHBondContact OG-N 3.45Å; S22-D25 PolarHBondContact OG-OD1 3.11Å; D25-G27 VanDerWaalsContact C-N 3.29Å; D25-G27 PolarHBondContact OD1-N 3.24Å
26G83.9Confident89.1Confident0 Ų050.7 Ų50.70%025%0.253CS..  trans73.415.5-175.700000115.1S22 K54S22-G26 WeakPolarHBondContact O-CA 3.35Å; S22-G26 PolarHBondContact O-N 3.08Å; G26-K54 WeakPolarHBondContact O-CD 3.35Å; G26-K54 PolarHBondContact O-NZ 3.25Å
27G87.6Confident89Confident25 Ų2550.1 Ų50.126%0.25825%0.254SS..  trans-63.2140.8172.100000112.1C21 S22 D25C21-G27 WeakPolarHBondContact CA-O 3.39Å; S22-G27 PolarHBondContact N-O 2.92Å; D25-G27 VanDerWaalsContact C-N 3.29Å; D25-G27 PolarHBondContact OD1-N 3.24Å
28L90.2Very high88.7Confident14 Ų1451.7 Ų51.77%0.07327%0.27CS..EExtended strand (participates in β ladder)trans-108.1133.2178-74.6163.1000110.9L19 W20 C21 D218 L219L19-L28 HydrophobicContact CD1-CB 4.42Å; L19-L28 HydrophobicContact CD1-CD2 4.12Å; L19-L28 HydrophobicContact CD2-CD2 4.2Å; L19-L28 HydrophobicContact CG-CD2 4.09Å; W20-L28 CarbonylContact O-C 3.53Å; W20-L28 WeakPolarHBondContact O-CA 3.36Å; C21-L28 HydrophobicContact CB-CD2 3.56Å; L28-D218 HydrophobicContact CB-CB 4.17Å; L28-D218 HydrophobicContact CD1-CB 4.03Å; L28-L219 HydrophobicContact CB-CD2 4.06Å; L28-L219 HydrophobicContact CD1-CD2 3.95Å; L28-L219 HydrophobicContact CD1-CG 4.05Å; L28-L219 HydrophobicContact CG-CD2 4.46Å
29Q90Very high88.4Confident93 Ų9352.2 Ų52.244%0.43527%0.274SS..EExtended strand (participates in β ladder)trans-136.6137.8-178.9-64.4-177.90.900110.9W20W20-Q29 HydrophobicContact CB-CB 4.44Å; W20-Q29 PolarHBondContact N-O 3.26Å; W20-Q29 PolarHBondContact O-N 2.7Å
30L90.8Very high87.9Confident47 Ų4761.5 Ų61.525%0.24631%0.309CS..EExtended strand (participates in β ladder)trans-87.7138.3168.8-66.8173.2000110.3L19 I222 T224 D226 V227 W230L19-L30 HydrophobicContact CB-CD2 4.47Å; L19-L30 HydrophobicContact CD1-CD2 3.85Å; L30-I222 HydrophobicContact CD1-CG2 4.18Å; L30-T224 WeakPolarHBondContact CD1-OG1 3.23Å; L30-D226 HydrophobicContact CD1-CB 4.17Å; L30-V227 HydrophobicContact CD1-CB 3.76Å; L30-V227 HydrophobicContact CD1-CG2 4.02Å; L30-W230 VanDerWaalsContact CD2-CD1 3.49Å; L30-W230 HydrophobicContact CD2-CG 4.43Å
31R89.8Confident87.5Confident83 Ų8366.4 Ų66.431%0.31334%0.336SS..EExtended strand (participates in β ladder)trans-143.9159.4172.6-58.9-169.4-173.9-162.71.5110.8A18 W20 D35A18-R31 PolarHBondContact N-O 2.66Å; A18-R31 PolarHBondContact O-N 3.27Å; W20-R31 HydrophobicContact CG-CG 4.31Å; R31-D35 HydrophobicContact CB-CB 4.19Å
32P88.9Confident87.2Confident71 Ų7168.8 Ų68.846%0.46135%0.351SS..EExtended strand (participates in β ladder)trans-56.5151.2164.7-24.135.7000111.8T34 D35P32-T34 WeakPolarHBondContact CB-OG1 3.25Å; P32-T34 PolarHBondContact O-N 2.7Å; P32-D35 WeakPolarHBondContact O-CB 3.46Å; P32-D35 PolarHBondContact O-N 2.95Å
33A87.8Confident87.2Confident17 Ų1772.3 Ų72.314%0.1437%0.368CS..G310 helixtrans-65.5-22.9175.300000113.5Q13 G15 E16 D35 L36Q13-A33 HydrophobicContact CG-CB 3.98Å; G15-A33 WeakPolarHBondContact O-CB 3.46Å; E16-A33 WeakPolarHBondContact O-CB 3.25Å; E16-A33 PolarHBondContact O-N 2.73Å; A33-D35 PolarHBondContact O-N 2.7Å; A33-L36 WeakPolarHBondContact O-CB 3.45Å; A33-L36 PolarHBondContact O-N 3.32Å
34T89.1Confident87.3Confident97 Ų9772.4 Ų72.460%0.59537%0.371SS*.G310 helixtrans-59.1-31.1173.545.20000112.8P32 L36 L37P32-T34 WeakPolarHBondContact CB-OG1 3.25Å; P32-T34 PolarHBondContact O-N 2.7Å; T34-L36 PolarHBondContact O-N 2.86Å; T34-L36 VanDerWaalsContact O-N 3.09Å; T34-L37 WeakPolarHBondContact O-CB 3.27Å; T34-L37 WeakPolarHBondContact O-CG 3.47Å; T34-L37 PolarHBondContact O-N 2.83Å; T34-L37 VanDerWaalsContact O-N 3.09Å
35D90Very high87.6Confident34 Ų3467 Ų6718%0.18235%0.353CS..G310 helixtrans-66.4-13.1-177.6-66.130.2000112.4W20 R31 P32 A33 L37 L38 A39W20-D35 WeakPolarHBondContact CH2-O 3.46Å; W20-D35 HydrophobicContact CZ2-CB 3.86Å; W20-D35 VanDerWaalsContact CZ2-O 3.31Å; W20-D35 WeakPolarHBondContact CZ2-O 3.26Å; R31-D35 HydrophobicContact CB-CB 4.19Å; P32-D35 WeakPolarHBondContact O-CB 3.46Å; P32-D35 PolarHBondContact O-N 2.95Å; A33-D35 PolarHBondContact O-N 2.7Å; D35-L37 PolarHBondContact O-N 3.41Å; D35-L38 HydrophobicContact CB-CD1 4.36Å; D35-L38 WeakPolarHBondContact O-CA 3.02Å; D35-L38 VanDerWaalsContact O-CB 3.28Å; D35-L38 WeakPolarHBondContact O-CB 3.49Å; D35-L38 PolarHBondContact O-N 3.18Å; D35-A39 PolarHBondContact O-N 2.95Å
36L87.9Confident88.1Confident25 Ų2562.1 Ų62.113%0.13133%0.326CS..G310 helixtrans-58.5-26.6171.7-173.263.1000111.7F4 I11 A33 T34 L38 A39 P42F4-L36 HydrophobicContact CB-CD1 4.34Å; F4-L36 HydrophobicContact CD1-CD2 4.26Å; F4-L36 HydrophobicContact CD2-CD1 4.3Å; F4-L36 HydrophobicContact CD2-CD2 4.07Å; F4-L36 HydrophobicContact CE1-CD2 3.95Å; F4-L36 HydrophobicContact CE2-CD2 3.74Å; F4-L36 HydrophobicContact CG-CD1 4.16Å; F4-L36 HydrophobicContact CG-CD2 4.32Å; F4-L36 HydrophobicContact CZ-CD2 3.67Å; I11-L36 HydrophobicContact CD1-CD1 3.67Å; I11-L36 HydrophobicContact CG2-CD1 4.34Å; A33-L36 WeakPolarHBondContact O-CB 3.45Å; A33-L36 PolarHBondContact O-N 3.32Å; T34-L36 PolarHBondContact O-N 2.86Å; T34-L36 VanDerWaalsContact O-N 3.09Å; L36-L38 PolarHBondContact O-N 2.57Å; L36-A39 HydrophobicContact CD1-CB 4.31Å; L36-A39 VanDerWaalsContact O-CB 3.29Å; L36-A39 WeakPolarHBondContact O-CB 3.41Å; L36-A39 PolarHBondContact O-N 2.81Å; L36-P42 HydrophobicContact CD1-CB 3.75Å; L36-P42 HydrophobicContact CD1-CG 4.24Å; L36-P42 HydrophobicContact CG-CB 4.45Å; L36-P42 HydrophobicContact CG-CG 4.46Å
37L84.6Confident88.5Confident160 Ų16065 Ų6584%0.83834%0.342SS*.G310 helixtrans-68.3-19172-60.9175.5000113.4T34 D35T34-L37 WeakPolarHBondContact O-CB 3.27Å; T34-L37 WeakPolarHBondContact O-CG 3.47Å; T34-L37 PolarHBondContact O-N 2.83Å; T34-L37 VanDerWaalsContact O-N 3.09Å; D35-L37 PolarHBondContact O-N 3.41Å
38L86.3Confident88.9Confident134 Ų13464 Ų6470%0.70233%0.331SS*.G310 helixtrans-90.8-7175.1-51176.3000112.2D35 L36D35-L38 HydrophobicContact CB-CD1 4.36Å; D35-L38 WeakPolarHBondContact O-CA 3.02Å; D35-L38 VanDerWaalsContact O-CB 3.28Å; D35-L38 WeakPolarHBondContact O-CB 3.49Å; D35-L38 PolarHBondContact O-N 3.18Å; L36-L38 PolarHBondContact O-N 2.57Å
39A85.8Confident89.1Confident13 Ų1367 Ų6711%0.10734%0.344CS..SBendtrans-74.1136177.100000110.8A6 I11 W20 D35 L36 N41 P42A6-A39 HydrophobicContact CB-CB 3.98Å; I11-A39 HydrophobicContact CD1-CB 3.8Å; W20-A39 HydrophobicContact CH2-CB 3.82Å; W20-A39 HydrophobicContact CZ3-CB 4.35Å; D35-A39 PolarHBondContact O-N 2.95Å; L36-A39 HydrophobicContact CD1-CB 4.31Å; L36-A39 VanDerWaalsContact O-CB 3.29Å; L36-A39 WeakPolarHBondContact O-CB 3.41Å; L36-A39 PolarHBondContact O-N 2.81Å; A39-N41 PolarHBondContact O-N 2.84Å; A39-P42 HydrophobicContact CB-CB 4.07Å; A39-P42 HydrophobicContact CB-CG 4.19Å; A39-P42 WeakPolarHBondContact O-CD 3.26Å
40W84.6Confident89.2Confident196 Ų19662.6 Ų62.674%0.74232%0.324SS*.SBendtrans-76.4112173.9-173.7-86.6000111K7K7-W40 HydrophobicContact CB-CB 4.31Å; K7-W40 PolarHBondContact N-O 2.87Å
41N83.7Confident89.4Confident112 Ų11260.4 Ų60.460%0.59931%0.312SS*.SBendtrans49.765.1177.7-166.243.1000114.1A39 I43A39-N41 PolarHBondContact O-N 2.84Å; N41-I43 PolarHBondContact O-N 2.93Å
42P88.8Confident89.7Confident49 Ų4956.5 Ų56.532%0.31830%0.298SS..  trans-74.5108.8-178.630.4-33.3000111.5Q5 L36 A39Q5-P42 WeakPolarHBondContact O-CA 3.26Å; L36-P42 HydrophobicContact CD1-CB 3.75Å; L36-P42 HydrophobicContact CD1-CG 4.24Å; L36-P42 HydrophobicContact CG-CB 4.45Å; L36-P42 HydrophobicContact CG-CG 4.46Å; A39-P42 HydrophobicContact CB-CB 4.07Å; A39-P42 HydrophobicContact CB-CG 4.19Å; A39-P42 WeakPolarHBondContact O-CD 3.26Å
43I88.8Confident89.9Confident87 Ų8753.1 Ų53.145%0.44628%0.276SS..EExtended strand (participates in β ladder)trans-89.8126175.3-59.9172.7000108.6F4 Q5 N41 L45F4-I43 CarbonylContact C-O 3.59Å; F4-I43 WeakPolarHBondContact CA-O 3.35Å; Q5-I43 PolarHBondContact N-O 2.95Å; Q5-I43 PolarHBondContact O-N 2.93Å; N41-I43 PolarHBondContact O-N 2.93Å; I43-L45 PolarHBondContact O-N 3.32Å
44C90.9Very high90.1Very high14 Ų1453 Ų5310%0.09527%0.272CS..EExtended strand (participates in β ladder)trans-71.8123.6171.7-169.50000109.5F4 H110 H111F4-C44 HydrophobicContact CD1-CB 3.81Å; F4-C44 HydrophobicContact CE1-CB 3.75Å; C44-H110 HydrophobicContact CB-CB 3.6Å; C44-H111 PolarHBondContact O-CE1 2.92Å; C44-H111 PolarHBondContact O-NE2 3.05Å
45L89.4Confident90.1Very high33 Ų3348.6 Ų48.617%0.17324%0.244CC..EExtended strand (participates in β ladder)trans-90.1-20.3176.5-64.5177.5000112.3L3 Q5 Y10 I43 P99 L102 L104L3-L45 HydrophobicContact CD2-CB 4.05Å; L3-L45 HydrophobicContact CD2-CD1 3.88Å; L3-L45 HydrophobicContact CG-CB 4.19Å; L3-L45 HydrophobicContact CG-CD1 4.13Å; L3-L45 PolarHBondContact O-N 3.09Å; Q5-L45 HydrophobicContact CB-CD1 3.79Å; Q5-L45 HydrophobicContact CB-CD2 4.34Å; Q5-L45 HydrophobicContact CB-CG 4.04Å; Y10-L45 HydrophobicContact CD1-CD1 4.24Å; Y10-L45 HydrophobicContact CE1-CD1 4.17Å; I43-L45 PolarHBondContact O-N 3.32Å; L45-P99 HydrophobicContact CD1-CG 4.39Å; L45-L102 HydrophobicContact CD1-CD1 3.84Å; L45-L104 HydrophobicContact CB-CD1 4.1Å
46G92.3Very high89.8Confident0 Ų049.6 Ų49.60%025%0.248CC..EExtended strand (participates in β ladder)trans135.2-151.3-179.200000112.9L3 E105L3-G46 PolarHBondContact N-O 3.42Å; G46-E105 CarbonylContact C-O 3.52Å; G46-E105 WeakPolarHBondContact CA-O 2.98Å
47L92.4Very high89Confident61 Ų6149.2 Ų49.232%0.31925%0.246SC..EExtended strand (participates in β ladder)trans-110.5144.4-177-59.6177.1000112.2M1 E2 E105 C107M1-L47 WeakPolarHBondContact O-CA 3.19Å; E2-L47 HydrophobicContact CG-CD2 3.77Å; L47-E105 WeakPolarHBondContact CB-O 3.47Å; L47-E105 WeakPolarHBondContact CG-O 3.32Å; L47-E105 PolarHBondContact N-O 3.21Å; L47-C107 HydrophobicContact CD2-CB 3.89Å; L47-C107 HydrophobicContact CG-CB 4.22Å
48V94.8Very high88.3Confident5 Ų544 Ų443%0.0322%0.218CC..  trans-136.7155.6171.9-61.70000110.8M1 L3 L12 L67 L104M1-V48 HydrophobicContact CB-CG2 3.93Å; M1-V48 WeakPolarHBondContact CB-O 3.28Å; M1-V48 PolarHBondContact N-O 3.09Å; M1-V48 PolarHBondContact O-N 2.66Å; L3-V48 HydrophobicContact CB-CG1 4.43Å; L3-V48 HydrophobicContact CB-CG2 4.43Å; L3-V48 HydrophobicContact CD2-CG1 4.3Å; L12-V48 HydrophobicContact CD2-CG2 3.78Å; V48-L67 HydrophobicContact CB-CB 4.48Å; V48-L67 HydrophobicContact CG1-CB 4.32Å; V48-L67 HydrophobicContact CG1-CD1 4.13Å; V48-L67 HydrophobicContact CG2-CD1 4.33Å; V48-L104 HydrophobicContact CG1-CD1 4.32Å; V48-L104 HydrophobicContact CG1-CD2 4.14Å
49E93.8Very high87.5Confident77 Ų7741.9 Ų41.936%0.3621%0.213SC..  trans-93.3-21.9-172.8-76.6-73.4-17600114.1I68 K71E49-I68 HydrophobicContact CB-CB 3.91Å; E49-I68 HydrophobicContact CB-CG2 3.71Å; E49-I68 PolarHBondContact N-O 2.86Å; E49-K71 HydrophobicContact CB-CD 4.39Å; E49-K71 VanDerWaalsContact CD-CE 3.42Å; E49-K71 HydrophobicContact CG-CD 4.02Å; E49-K71 HydrophobicContact CG-CG 4.26Å; E49-K71 VanDerWaalsContact OE1-CE 3.32Å; E49-K71 WeakPolarHBondContact OE1-CE 3.42Å; E49-K71 IonicContact OE1-NZ 2.86Å; E49-K71 PolarHBondContact OE1-NZ 3.1Å; E49-K71 VanDerWaalsContact OE2-CE 3.26Å; E49-K71 WeakPolarHBondContact OE2-CE 3.37Å; E49-K71 IonicContact OE2-NZ 2.81Å; E49-K71 PolarHBondContact OE2-NZ 3.16Å
50G93.4Very high86.7Confident0 Ų046.1 Ų46.10%023%0.234CC..EExtended strand (participates in β ladder)trans173.8169.6-175.500000113.7L67 I68G50-L67 CarbonylContact O-C 3.48Å; G50-L67 WeakPolarHBondContact O-CA 3.47Å; G50-I68 PolarHBondContact O-N 3.43Å
51V94.6Very high86.2Confident1 Ų138.3 Ų38.31%0.00621%0.207CC..EExtended strand (participates in β ladder)trans-96.6129.3173.1-179.70000108.7L12 L19 L65 L67 W230L12-V51 HydrophobicContact CD2-CG2 3.79Å; L19-V51 HydrophobicContact CD2-CG2 4Å; V51-L65 HydrophobicContact CG1-CD1 4.32Å; V51-L67 HydrophobicContact CB-CD2 4.31Å; V51-L67 HydrophobicContact CG1-CD2 4.37Å; V51-L67 HydrophobicContact CG2-CD2 3.91Å; V51-W230 HydrophobicContact CG2-CE3 4.29Å
52I95.3Very high85.8Confident1 Ų135 Ų351%0.00519%0.192CC..EExtended strand (participates in β ladder)trans-89.1-38170-58.7-170.2000109.8I66 I68 I89 F170 N212 M215 I216 M234I52-I66 HydrophobicContact CB-CB 4.32Å; I52-I66 HydrophobicContact CB-CG2 3.98Å; I52-I66 WeakPolarHBondContact CB-O 3.21Å; I52-I66 HydrophobicContact CD1-CG2 4.06Å; I52-I66 HydrophobicContact CG1-CG2 4.37Å; I52-I66 HydrophobicContact CG2-CG2 4.35Å; I52-I66 PolarHBondContact N-O 2.74Å; I52-I68 HydrophobicContact CD1-CG1 3.9Å; I52-I68 HydrophobicContact CG1-CD1 4.4Å; I52-I68 HydrophobicContact CG1-CG1 3.54Å; I52-I89 HydrophobicContact CD1-CG2 3.49Å; I52-I89 VanDerWaalsContact CD1-CG2 3.49Å; I52-F170 HydrophobicContact CD1-CD1 4.1Å; I52-F170 HydrophobicContact CD1-CE1 3.64Å; I52-F170 HydrophobicContact CD1-CZ 4.14Å; I52-F170 HydrophobicContact CG2-CE1 4.3Å; I52-F170 HydrophobicContact CG2-CZ 4.01Å; I52-N212 HydrophobicContact CG2-CB 4.44Å; I52-N212 PolarHBondContact O-ND2 2.81Å; I52-N212 VanDerWaalsContact O-ND2 3.17Å; I52-M215 HydrophobicContact CG2-CE 4.03Å; I52-M215 HydrophobicContact CG2-SD 4.41Å; I52-I216 VanDerWaalsContact O-CG2 3.27Å; I52-I216 WeakPolarHBondContact O-CG2 3.17Å; I52-M234 HydrophobicContact CB-SD 4.33Å; I52-M234 HydrophobicContact CD1-CE 4.36Å; I52-M234 HydrophobicContact CD1-SD 4.42Å; I52-M234 HydrophobicContact CG1-CE 4.49Å; I52-M234 HydrophobicContact CG1-SD 4.03Å; I52-M234 HydrophobicContact CG2-SD 3.92Å
53G93.9Very high85.7Confident0 Ų035.4 Ų35.40%019%0.187CC..EExtended strand (participates in β ladder)trans143.9-170.417700000111.8I66 M215G53-I66 PolarHBondContact N-O 2.71Å; G53-I66 WeakPolarHBondContact O-CA 3.29Å; G53-I66 WeakPolarHBondContact O-CB 3.47Å; G53-I66 PolarHBondContact O-N 3.32Å; G53-M215 CarbonylContact C-O 3.5Å; G53-M215 WeakPolarHBondContact CA-O 3.46Å
54K91.5Very high85.7Confident15 Ų1532 Ų327%0.06517%0.168CC..EExtended strand (participates in β ladder)trans-109.3161.4170.367.1176.4-169.3-169.80111.5G26 W63 W64 M215 D218G26-K54 WeakPolarHBondContact O-CD 3.35Å; G26-K54 PolarHBondContact O-NZ 3.25Å; K54-W63 HydrophobicContact CB-CE3 4.01Å; K54-W63 HydrophobicContact CB-CZ3 4.48Å; K54-W63 HydrophobicContact CD-CD2 4.09Å; K54-W63 HydrophobicContact CD-CE3 3.53Å; K54-W63 HydrophobicContact CD-CZ3 3.84Å; K54-W63 HydrophobicContact CG-CE3 3.6Å; K54-W63 HydrophobicContact CG-CZ3 3.71Å; K54-W64 CarbonylContact C-O 3.49Å; K54-W64 WeakPolarHBondContact CA-O 3.43Å; K54-M215 PolarHBondContact N-O 2.85Å; K54-M215 WeakPolarHBondContact O-CA 3.23Å; K54-M215 WeakPolarHBondContact O-CB 3.47Å; K54-D218 WeakPolarHBondContact CE-OD1 3.14Å; K54-D218 IonicContact NZ-OD1 2.75Å; K54-D218 PolarHBondContact NZ-OD1 2.91Å; K54-D218 IonicContact NZ-OD2 2.79Å; K54-D218 PolarHBondContact NZ-OD2 3.08Å
55I88.8Confident85.8Confident3 Ų331.3 Ų31.32%0.01516%0.164CC..EExtended strand (participates in β ladder)trans-144.3147.4176.3-160.2168.8000109.7W63 W64 I66 L564 M565I55-W63 VanDerWaalsContact C-CE3 3.4Å; I55-W64 HydrophobicContact CG2-CB 4.05Å; I55-W64 PolarHBondContact N-O 3.01Å; I55-W64 PolarHBondContact O-N 3.14Å; I55-I66 HydrophobicContact CB-CD1 4.24Å; I55-I66 HydrophobicContact CG2-CD1 3.71Å; I55-I66 HydrophobicContact CG2-CG1 4.48Å; I55-L564 HydrophobicContact CD1-CB 3.79Å; I55-L564 HydrophobicContact CG1-CB 4.18Å; I55-M565 HydrophobicContact CD1-CG 3.87Å
56Q83.3Confident86Confident56 Ų5629.8 Ų29.826%0.26216%0.156SC..  trans-120130.3169.6-153.3-172.711.800108.5H58 S59 L61 W63Q56-H58 WeakPolarHBondContact CG-O 3.44Å; Q56-H58 PolarHBondContact NE2-O 3.25Å; Q56-S59 PolarHBondContact NE2-O 3.48Å; Q56-L61 WeakPolarHBondContact CG-O 3.2Å; Q56-L61 PolarHBondContact NE2-O 2.96Å; Q56-W63 HydrophobicContact CB-CD2 3.72Å; Q56-W63 HydrophobicContact CB-CE3 3.79Å; Q56-W63 HydrophobicContact CB-CG 4.32Å; Q56-W63 HydrophobicContact CB-CH2 4.06Å; Q56-W63 HydrophobicContact CB-CZ2 3.99Å; Q56-W63 HydrophobicContact CB-CZ3 3.96Å; Q56-W63 HydrophobicContact CG-CD2 4.07Å; Q56-W63 HydrophobicContact CG-CG 4.19Å
57L71.8Confident86.1Confident16 Ų1629.8 Ų29.88%0.08416%0.156CC..SBendtrans-83.8-25.7-177-56.6-176.1000113.3L61 W64 E159 L162 L564L57-L61 HydrophobicContact CB-CD1 4.06Å; L57-W64 HydrophobicContact CD1-CE3 4.28Å; L57-W64 HydrophobicContact CD1-CH2 3.59Å; L57-W64 HydrophobicContact CD1-CZ2 3.98Å; L57-W64 HydrophobicContact CD1-CZ3 3.74Å; L57-W64 HydrophobicContact CG-CZ3 4.46Å; L57-E159 HydrophobicContact CD1-CB 4.3Å; L57-E159 HydrophobicContact CD1-CG 3.97Å; L57-L162 HydrophobicContact CB-CD1 4.36Å; L57-L162 HydrophobicContact CD1-CB 4.24Å; L57-L162 HydrophobicContact CD1-CD1 4.26Å; L57-L162 HydrophobicContact CD2-CB 4.37Å; L57-L162 HydrophobicContact CD2-CD1 4.3Å; L57-L564 HydrophobicContact CD2-CD1 3.77Å
58H71.2Confident86.3Confident52 Ų5226.9 Ų26.924%0.24114%0.141CC..SBendtrans-164.7151.4-179.4-164.8-68.4000107.8Q56 D60 L61 Y575Q56-H58 WeakPolarHBondContact CG-O 3.44Å; Q56-H58 PolarHBondContact NE2-O 3.25Å; H58-D60 IonicContact CE1-OD1 3.58Å; H58-D60 PolarHBondContact CE1-OD1 3.41Å; H58-D60 IonicContact CE1-OD2 3.94Å; H58-D60 PolarHBondContact CE1-OD2 3.06Å; H58-D60 VanDerWaalsContact CE1-OD2 3.31Å; H58-D60 PolarHBondContact ND1-N 3.19Å; H58-D60 IonicContact ND1-OD1 2.62Å; H58-D60 PolarHBondContact ND1-OD1 2.78Å; H58-D60 IonicContact ND1-OD2 3.97Å; H58-D60 PolarHBondContact O-N 2.87Å; H58-D60 VanDerWaalsContact O-N 3.15Å; H58-L61 HydrophobicContact CB-CB 4.31Å; H58-L61 HydrophobicContact CB-CD1 3.89Å; H58-L61 HydrophobicContact CB-CG 4.04Å; H58-L61 PolarHBondContact O-N 3.06Å; H58-Y575 PolarHBondContact CD2-OH 3.34Å; H58-Y575 VanDerWaalsContact CD2-OH 3.32Å; H58-Y575 AromaticContact NE2-CE2 3.86Å; H58-Y575 AromaticContact NE2-CZ 3.83Å; H58-Y575 PolarHBondContact NE2-OH 3.38Å
59S69.2Low86.2Confident88 Ų8828.8 Ų28.862%0.61515%0.147SC*.THydrogen-bonded Turntrans-46.7-43176.644.90000114.4Q56 L61Q56-S59 PolarHBondContact NE2-O 3.48Å; S59-L61 VanDerWaalsContact C-N 3.3Å; S59-L61 PolarHBondContact O-N 2.73Å
60D68.1Low86.1Confident102 Ų10227.5 Ų27.555%0.54514%0.142SC..THydrogen-bonded Turntrans-83.9-1.7-174.6-27.5-16000113.3H58 K155H58-D60 IonicContact CE1-OD1 3.58Å; H58-D60 PolarHBondContact CE1-OD1 3.41Å; H58-D60 IonicContact CE1-OD2 3.94Å; H58-D60 PolarHBondContact CE1-OD2 3.06Å; H58-D60 VanDerWaalsContact CE1-OD2 3.31Å; H58-D60 PolarHBondContact ND1-N 3.19Å; H58-D60 IonicContact ND1-OD1 2.62Å; H58-D60 PolarHBondContact ND1-OD1 2.78Å; H58-D60 IonicContact ND1-OD2 3.97Å; H58-D60 PolarHBondContact O-N 2.87Å; H58-D60 VanDerWaalsContact O-N 3.15Å; D60-K155 IonicContact OD2-NZ 2.7Å; D60-K155 PolarHBondContact OD2-NZ 2.75Å
61L73.5Confident86.2Confident32 Ų3231.3 Ų31.317%0.16816%0.158CC..SBendtrans-106.8148.8-178.4-70.3178.1000110.7Q56 L57 H58 S59 E159Q56-L61 WeakPolarHBondContact CG-O 3.2Å; Q56-L61 PolarHBondContact NE2-O 2.96Å; L57-L61 HydrophobicContact CB-CD1 4.06Å; H58-L61 HydrophobicContact CB-CB 4.31Å; H58-L61 HydrophobicContact CB-CD1 3.89Å; H58-L61 HydrophobicContact CB-CG 4.04Å; H58-L61 PolarHBondContact O-N 3.06Å; S59-L61 VanDerWaalsContact C-N 3.3Å; S59-L61 PolarHBondContact O-N 2.73Å; L61-E159 HydrophobicContact CD1-CB 4.34Å
62P76.8Confident86.2Confident43 Ų4333.1 Ų33.128%0.27917%0.173SC..  trans-61.3146.817826.2-34.4000111.4L94P62-L94 VanDerWaalsContact CB-O 3.29Å; P62-L94 WeakPolarHBondContact CB-O 3.23Å
63W86.1Confident86.3Confident57 Ų5737.7 Ų37.722%0.21620%0.197CC..  trans-60.6147.1165.6-77.390.5000110.3K54 I55 Q56 L94K54-W63 HydrophobicContact CB-CE3 4.01Å; K54-W63 HydrophobicContact CB-CZ3 4.48Å; K54-W63 HydrophobicContact CD-CD2 4.09Å; K54-W63 HydrophobicContact CD-CE3 3.53Å; K54-W63 HydrophobicContact CD-CZ3 3.84Å; K54-W63 HydrophobicContact CG-CE3 3.6Å; K54-W63 HydrophobicContact CG-CZ3 3.71Å; I55-W63 VanDerWaalsContact C-CE3 3.4Å; Q56-W63 HydrophobicContact CB-CD2 3.72Å; Q56-W63 HydrophobicContact CB-CE3 3.79Å; Q56-W63 HydrophobicContact CB-CG 4.32Å; Q56-W63 HydrophobicContact CB-CH2 4.06Å; Q56-W63 HydrophobicContact CB-CZ2 3.99Å; Q56-W63 HydrophobicContact CB-CZ3 3.96Å; Q56-W63 HydrophobicContact CG-CD2 4.07Å; Q56-W63 HydrophobicContact CG-CG 4.19Å; W63-L94 HydrophobicContact CB-CB 4.31Å; W63-L94 HydrophobicContact CB-CD1 3.8Å; W63-L94 HydrophobicContact CB-CG 4.31Å; W63-L94 WeakPolarHBondContact O-CA 3.24Å; W63-L94 WeakPolarHBondContact O-CB 3.36Å; W63-L94 WeakPolarHBondContact O-CG 3.25Å; W63-L94 PolarHBondContact O-N 2.85Å
64W89Confident86.4Confident15 Ų1539.6 Ų39.66%0.05721%0.208CC..EExtended strand (participates in β ladder)trans-119.5126.5175.8-69.33.4000110K54 I55 L57 V91 L92 E159 L163K54-W64 CarbonylContact C-O 3.49Å; K54-W64 WeakPolarHBondContact CA-O 3.43Å; I55-W64 HydrophobicContact CG2-CB 4.05Å; I55-W64 PolarHBondContact N-O 3.01Å; I55-W64 PolarHBondContact O-N 3.14Å; L57-W64 HydrophobicContact CD1-CE3 4.28Å; L57-W64 HydrophobicContact CD1-CH2 3.59Å; L57-W64 HydrophobicContact CD1-CZ2 3.98Å; L57-W64 HydrophobicContact CD1-CZ3 3.74Å; L57-W64 HydrophobicContact CG-CZ3 4.46Å; W64-V91 HydrophobicContact CB-CG1 4.07Å; W64-V91 HydrophobicContact CD2-CG1 4.12Å; W64-V91 HydrophobicContact CE3-CG1 3.69Å; W64-V91 HydrophobicContact CG-CG1 4.34Å; W64-V91 HydrophobicContact CZ3-CG1 4.48Å; W64-L92 CarbonylContact C-O 3.53Å; W64-L92 VanDerWaalsContact CA-O 3.26Å; W64-L92 WeakPolarHBondContact CA-O 3.31Å; W64-E159 HydrophobicContact CH2-CG 3.67Å; W64-E159 HydrophobicContact CZ2-CG 3.43Å; W64-E159 VanDerWaalsContact CZ2-CG 3.43Å; W64-E159 WeakPolarHBondContact CZ2-OE1 3.2Å; W64-L163 HydrophobicContact CE3-CD1 4.24Å; W64-L163 HydrophobicContact CH2-CB 3.67Å; W64-L163 HydrophobicContact CH2-CD1 4.31Å; W64-L163 HydrophobicContact CH2-CD2 4.01Å; W64-L163 HydrophobicContact CH2-CG 4.2Å; W64-L163 HydrophobicContact CZ3-CB 3.58Å; W64-L163 HydrophobicContact CZ3-CD1 3.65Å; W64-L163 HydrophobicContact CZ3-CD2 4.19Å; W64-L163 HydrophobicContact CZ3-CG 3.98Å
65L92.3Very high86.6Confident1 Ų139.7 Ų39.71%0.00521%0.214CC..EExtended strand (participates in β ladder)trans-89129.2175.217463.6000109.9L12 C21 V51 L67 V91 L92 L94L12-L65 HydrophobicContact CD1-CD2 4.29Å; C21-L65 HydrophobicContact CB-CD2 3.94Å; V51-L65 HydrophobicContact CG1-CD1 4.32Å; L65-L67 HydrophobicContact CD1-CD2 3.97Å; L65-L67 HydrophobicContact CD2-CD1 4.48Å; L65-L67 HydrophobicContact CD2-CD2 4.17Å; L65-L67 HydrophobicContact CD2-CG 4.49Å; L65-L67 HydrophobicContact CG-CD2 3.88Å; L65-L67 HydrophobicContact CG-CG 4.15Å; L65-V91 WeakPolarHBondContact O-CA 3.17Å; L65-L92 HydrophobicContact CB-CB 4.35Å; L65-L92 HydrophobicContact CD2-CD1 4.27Å; L65-L92 PolarHBondContact N-O 2.83Å; L65-L92 PolarHBondContact O-N 2.75Å; L65-L94 HydrophobicContact CB-CD1 4.35Å; L65-L94 HydrophobicContact CB-CD2 3.84Å; L65-L94 HydrophobicContact CB-CG 4.33Å
66I93.9Very high86.9Confident0 Ų043.7 Ų43.70%023%0.231CC..EExtended strand (participates in β ladder)trans-115121.5-175.2-56171.1000109.3I52 G53 I55 I89 A90 V91 L166 M215I52-I66 HydrophobicContact CB-CB 4.32Å; I52-I66 HydrophobicContact CB-CG2 3.98Å; I52-I66 WeakPolarHBondContact CB-O 3.21Å; I52-I66 HydrophobicContact CD1-CG2 4.06Å; I52-I66 HydrophobicContact CG1-CG2 4.37Å; I52-I66 HydrophobicContact CG2-CG2 4.35Å; I52-I66 PolarHBondContact N-O 2.74Å; G53-I66 PolarHBondContact N-O 2.71Å; G53-I66 WeakPolarHBondContact O-CA 3.29Å; G53-I66 WeakPolarHBondContact O-CB 3.47Å; G53-I66 PolarHBondContact O-N 3.32Å; I55-I66 HydrophobicContact CB-CD1 4.24Å; I55-I66 HydrophobicContact CG2-CD1 3.71Å; I55-I66 HydrophobicContact CG2-CG1 4.48Å; I66-I89 HydrophobicContact CG2-CB 4.24Å; I66-I89 HydrophobicContact CG2-CD1 4.03Å; I66-I89 HydrophobicContact CG2-CG2 4.41Å; I66-A90 WeakPolarHBondContact CA-O 3.27Å; I66-V91 HydrophobicContact CG1-CG1 4.33Å; I66-V91 HydrophobicContact CG1-CG2 4.4Å; I66-L166 HydrophobicContact CD1-CD1 4.42Å; I66-L166 HydrophobicContact CD1-CD2 3.82Å; I66-M215 HydrophobicContact CD1-CE 3.59Å
67L95.3Very high87.4Confident0 Ų041.1 Ų41.10%022%0.219CC..EExtended strand (participates in β ladder)trans-121.5148.2-174.1-55.9179.5000110.8L3 L12 V48 G50 V51 L65 R69 I89 A90 L92L3-L67 HydrophobicContact CD1-CD1 4.06Å; L3-L67 HydrophobicContact CD2-CD1 4.08Å; L12-L67 HydrophobicContact CD1-CD2 4.45Å; L12-L67 HydrophobicContact CD2-CD1 4.24Å; L12-L67 HydrophobicContact CD2-CD2 3.85Å; V48-L67 HydrophobicContact CB-CB 4.48Å; V48-L67 HydrophobicContact CG1-CB 4.32Å; V48-L67 HydrophobicContact CG1-CD1 4.13Å; V48-L67 HydrophobicContact CG2-CD1 4.33Å; G50-L67 CarbonylContact O-C 3.48Å; G50-L67 WeakPolarHBondContact O-CA 3.47Å; V51-L67 HydrophobicContact CB-CD2 4.31Å; V51-L67 HydrophobicContact CG1-CD2 4.37Å; V51-L67 HydrophobicContact CG2-CD2 3.91Å; L65-L67 HydrophobicContact CD1-CD2 3.97Å; L65-L67 HydrophobicContact CD2-CD1 4.48Å; L65-L67 HydrophobicContact CD2-CD2 4.17Å; L65-L67 HydrophobicContact CD2-CG 4.49Å; L65-L67 HydrophobicContact CG-CD2 3.88Å; L65-L67 HydrophobicContact CG-CG 4.15Å; L67-R69 PolarHBondContact O-N 2.77Å; L67-I89 CarbonylContact O-C 3.41Å; L67-I89 WeakPolarHBondContact O-CA 3.45Å; L67-I89 WeakPolarHBondContact O-CB 3.39Å; L67-A90 PolarHBondContact N-O 2.87Å; L67-A90 PolarHBondContact O-N 2.86Å; L67-L92 HydrophobicContact CD1-CD1 3.74Å
68I95.3Very high88.3Confident0 Ų041.8 Ų41.80%022%0.224CC..EExtended strand (participates in β ladder)trans-73.7111.6170.8-51.5176.7000107.4E49 G50 I52 K71 V86 Y178 I232E49-I68 HydrophobicContact CB-CB 3.91Å; E49-I68 HydrophobicContact CB-CG2 3.71Å; E49-I68 PolarHBondContact N-O 2.86Å; G50-I68 PolarHBondContact O-N 3.43Å; I52-I68 HydrophobicContact CD1-CG1 3.9Å; I52-I68 HydrophobicContact CG1-CD1 4.4Å; I52-I68 HydrophobicContact CG1-CG1 3.54Å; I68-K71 HydrophobicContact CG2-CB 4.46Å; I68-V86 HydrophobicContact CD1-CG2 4.03Å; I68-V86 HydrophobicContact CG1-CG2 4.11Å; I68-V86 HydrophobicContact CG2-CG1 4.3Å; I68-V86 HydrophobicContact CG2-CG2 3.99Å; I68-Y178 HydrophobicContact CD1-CD1 4.43Å; I68-Y178 HydrophobicContact CD1-CE1 3.76Å; I68-Y178 HydrophobicContact CD1-CE2 4.43Å; I68-I232 HydrophobicContact CD1-CD1 4.27Å
69R93.4Very high89.1Confident45 Ų4542.4 Ų42.417%0.1725%0.245CC..EExtended strand (participates in β ladder)trans-86.2-44.9177.9172.6179.6164.7-148.2-10.3111.2L67 K88 A90 E103 L104L67-R69 PolarHBondContact O-N 2.77Å; R69-K88 HydrophobicContact CB-CB 4.2Å; R69-K88 HydrophobicContact CG-CB 4.41Å; R69-K88 PolarHBondContact N-O 2.68Å; R69-A90 HydrophobicContact CB-CB 4.21Å; R69-E103 VanDerWaalsContact CZ-CB 3.48Å; R69-E103 IonicContact CZ-OE2 2.72Å; R69-E103 PolarHBondContact NE-O 3.12Å; R69-E103 IonicContact NH1-OE2 2.66Å; R69-E103 PolarHBondContact NH1-OE2 2.65Å; R69-E103 PolarHBondContact NH2-O 3.37Å; R69-E103 IonicContact NH2-OE2 2.67Å; R69-E103 PolarHBondContact NH2-OE2 2.98Å; R69-L104 HydrophobicContact CB-CD2 4.45Å; R69-L104 HydrophobicContact CG-CD2 3.87Å
70Q92.5Very high90.2Very high51 Ų5143.7 Ų43.724%0.23825%0.245CC..EExtended strand (participates in β ladder)trans-141.1144.5174.9-73.1-177.4-39.700110.3T87 K88 E105Q70-T87 VanDerWaalsContact C-OG1 3.28Å; Q70-T87 PolarHBondContact O-N 2.85Å; Q70-T87 PolarHBondContact O-OG1 3.04Å; Q70-T87 VanDerWaalsContact O-OG1 3.09Å; Q70-K88 HydrophobicContact CB-CB 4.16Å; Q70-K88 HydrophobicContact CB-CG 4.44Å; Q70-K88 PolarHBondContact N-O 2.86Å; Q70-K88 PolarHBondContact O-N 2.85Å; Q70-K88 VanDerWaalsContact O-N 3.1Å; Q70-K88 VanDerWaalsContact OE1-CE 3.27Å; Q70-E105 PolarHBondContact NE2-OE1 3.46Å
71K94Very high91.4Very high80 Ų8041.3 Ų41.335%0.34823%0.23SC..EExtended strand (participates in β ladder)trans-122.7164.317572-170-176.5-165.10109.9E49 I68 C84 K85 Y178E49-K71 HydrophobicContact CB-CD 4.39Å; E49-K71 VanDerWaalsContact CD-CE 3.42Å; E49-K71 HydrophobicContact CG-CD 4.02Å; E49-K71 HydrophobicContact CG-CG 4.26Å; E49-K71 VanDerWaalsContact OE1-CE 3.32Å; E49-K71 WeakPolarHBondContact OE1-CE 3.42Å; E49-K71 IonicContact OE1-NZ 2.86Å; E49-K71 PolarHBondContact OE1-NZ 3.1Å; E49-K71 VanDerWaalsContact OE2-CE 3.26Å; E49-K71 WeakPolarHBondContact OE2-CE 3.37Å; E49-K71 IonicContact OE2-NZ 2.81Å; E49-K71 PolarHBondContact OE2-NZ 3.16Å; I68-K71 HydrophobicContact CG2-CB 4.46Å; K71-C84 HydrophobicContact CD-CB 4.41Å; K71-K85 CarbonylContact C-O 3.58Å; K71-K85 VanDerWaalsContact CA-O 3.27Å; K71-K85 WeakPolarHBondContact CA-O 3.12Å; K71-Y178 WeakPolarHBondContact CD-OH 3.38Å
72A95.3Very high92.6Very high38 Ų3844.2 Ų44.231%0.31424%0.243SC..EExtended strand (participates in β ladder)trans-129.8138165.800000109.6V74 C84 K85 T87A72-V74 PolarHBondContact O-N 3.22Å; A72-C84 WeakPolarHBondContact O-CA 3.33Å; A72-K85 PolarHBondContact N-O 3.01Å; A72-K85 PolarHBondContact O-N 3.22Å; A72-T87 HydrophobicContact CB-CG2 3.72Å
73L96.7Very high93.6Very high98 Ų9842.2 Ų42.251%0.51323%0.23SC..EExtended strand (participates in β ladder)trans-67.6129.5169-176.667000108.6G75 E82L73-G75 WeakPolarHBondContact CD1-O 3.29Å; L73-E82 HydrophobicContact CD1-CB 3.81Å; L73-E82 HydrophobicContact CD1-CG 4.03Å
74V95.8Very high94.1Very high39 Ų3940 Ų4024%0.23622%0.223CC..EExtended strand (participates in β ladder)trans-89-34.5175-178.90000110.6A72 V83 K85 Y177 V239A72-V74 PolarHBondContact O-N 3.22Å; V74-V83 HydrophobicContact CB-CB 4.4Å; V74-V83 HydrophobicContact CB-CG1 4.2Å; V74-V83 WeakPolarHBondContact CB-O 3.44Å; V74-V83 HydrophobicContact CG2-CG1 4.25Å; V74-V83 PolarHBondContact N-O 3.16Å; V74-K85 HydrophobicContact CG2-CB 3.7Å; V74-Y177 HydrophobicContact CG2-CD1 3.87Å; V74-Y177 HydrophobicContact CG2-CE1 3.78Å; V74-V239 HydrophobicContact CG1-CB 4.36Å; V74-V239 HydrophobicContact CG1-CG1 4.17Å; V74-V239 WeakPolarHBondContact CG1-O 3.21Å
75G95.4Very high94.4Very high18 Ų1840.9 Ų40.919%0.18623%0.227CC..EExtended strand (participates in β ladder)trans156.3-169.5-175.900000109.8L73 V83L73-G75 WeakPolarHBondContact CD1-O 3.29Å; G75-V83 PolarHBondContact O-N 2.83Å
76K96Very high94.6Very high86 Ų8640.9 Ų40.937%0.37423%0.227SC..EExtended strand (participates in β ladder)trans-117.1136.5174.6-72.6178.1164.6-172.20110D80 H81 E82K76-D80 VanDerWaalsContact CD-OD1 3.28Å; K76-D80 WeakPolarHBondContact CD-OD1 3.08Å; K76-D80 WeakPolarHBondContact CE-OD1 3.44Å; K76-D80 IonicContact NZ-OD1 2.74Å; K76-D80 PolarHBondContact NZ-OD1 3.46Å; K76-H81 WeakPolarHBondContact CA-O 3.4Å; K76-E82 HydrophobicContact CG-CG 4.06Å
77L94.9Very high94.5Very high3 Ų342.5 Ų42.52%0.01624%0.237CC..EExtended strand (participates in β ladder)trans-84.2165.8164.9-69.4176.3000109.6D80 H81 V83 Y182 L184 I241 A279 I281 L313L77-D80 PolarHBondContact O-N 2.93Å; L77-H81 HydrophobicContact CB-CB 4.02Å; L77-H81 PolarHBondContact N-O 3.35Å; L77-H81 PolarHBondContact O-N 2.94Å; L77-V83 HydrophobicContact CD1-CG2 3.71Å; L77-V83 HydrophobicContact CG-CG2 3.83Å; L77-Y182 HydrophobicContact CD1-CD1 3.59Å; L77-Y182 HydrophobicContact CD1-CE1 3.6Å; L77-Y182 HydrophobicContact CD1-CG 4.09Å; L77-L184 HydrophobicContact CD1-CD2 3.89Å; L77-I241 HydrophobicContact CD2-CD1 3.76Å; L77-I241 HydrophobicContact CD2-CG1 4.21Å; L77-I241 HydrophobicContact CG-CD1 3.92Å; L77-A279 HydrophobicContact CD2-CB 3.71Å; L77-I281 HydrophobicContact CD1-CD1 4.27Å; L77-L313 HydrophobicContact CD2-CD1 4.05Å
78P90.2Very high94.4Very high29 Ų2945.6 Ų45.619%0.18825%0.251CS..THydrogen-bonded Turntrans-51141.6179.4-28.938.2000112.3H81 H315 T320P78-H81 PolarHBondContact O-CD2 2.83Å; P78-H315 HydrophobicContact CG-CB 3.74Å; P78-T320 HydrophobicContact CG-CG2 4.41Å
79G87.2Confident94.3Very high65 Ų6546 Ų4667%0.6725%0.253SS*.THydrogen-bonded Turntrans79.529.4-172.200000114.5H81G79-H81 PolarHBondContact O-N 2.9Å; G79-H81 VanDerWaalsContact O-N 3.1Å
80D91.8Very high94.2Very high116 Ų11644.1 Ų44.162%0.6225%0.247SC*.THydrogen-bonded Turntrans59.817.5178.4-92.6-65.2000115.6K76 L77 E82K76-D80 VanDerWaalsContact CD-OD1 3.28Å; K76-D80 WeakPolarHBondContact CD-OD1 3.08Å; K76-D80 WeakPolarHBondContact CE-OD1 3.44Å; K76-D80 IonicContact NZ-OD1 2.74Å; K76-D80 PolarHBondContact NZ-OD1 3.46Å; L77-D80 PolarHBondContact O-N 2.93Å; D80-E82 PolarHBondContact O-N 3.42Å
81H95.1Very high94.1Very high51 Ų5143.1 Ų43.124%0.23624%0.244CC..EExtended strand (participates in β ladder)trans-69.396.7-176.1-74.4-51.4000112.8K76 L77 P78 G79 V83 T181 Y182K76-H81 WeakPolarHBondContact CA-O 3.4Å; L77-H81 HydrophobicContact CB-CB 4.02Å; L77-H81 PolarHBondContact N-O 3.35Å; L77-H81 PolarHBondContact O-N 2.94Å; P78-H81 PolarHBondContact O-CD2 2.83Å; G79-H81 PolarHBondContact O-N 2.9Å; G79-H81 VanDerWaalsContact O-N 3.1Å; H81-V83 PolarHBondContact O-N 2.82Å; H81-T181 PolarHBondContact CE1-O 3.03Å; H81-T181 WeakPolarHBondContact ND1-CB 3.39Å; H81-T181 PolarHBondContact ND1-O 3.33Å; H81-T181 PolarHBondContact ND1-OG1 3.28Å; H81-Y182 HydrophobicContact CB-CD2 4.46Å; H81-Y182 HydrophobicContact CB-CG 4.38Å; H81-Y182 AromaticContact CD2-CD2 3.54Å
82E97.1Very high93.8Very high94 Ų9439.3 Ų39.344%0.43923%0.228SC..EExtended strand (participates in β ladder)trans-62.9129.6177.5-65.7-168.4163.100112.7L73 K76 D80 S179L73-E82 HydrophobicContact CD1-CB 3.81Å; L73-E82 HydrophobicContact CD1-CG 4.03Å; K76-E82 HydrophobicContact CG-CG 4.06Å; D80-E82 PolarHBondContact O-N 3.42Å; E82-S179 VanDerWaalsContact O-CB 3.23Å; E82-S179 WeakPolarHBondContact O-CB 3.37Å; E82-S179 PolarHBondContact O-OG 3.45Å
83V97.8Very high93.4Very high0 Ų039.1 Ų39.10%022%0.224CC..EExtended strand (participates in β ladder)trans-107.9122.5173.1176.40000110V74 G75 L77 H81 L184 V239 I241V74-V83 HydrophobicContact CB-CB 4.4Å; V74-V83 HydrophobicContact CB-CG1 4.2Å; V74-V83 WeakPolarHBondContact CB-O 3.44Å; V74-V83 HydrophobicContact CG2-CG1 4.25Å; V74-V83 PolarHBondContact N-O 3.16Å; G75-V83 PolarHBondContact O-N 2.83Å; L77-V83 HydrophobicContact CD1-CG2 3.71Å; L77-V83 HydrophobicContact CG-CG2 3.83Å; H81-V83 PolarHBondContact O-N 2.82Å; V83-L184 HydrophobicContact CG1-CD1 3.94Å; V83-L184 HydrophobicContact CG2-CD1 4.5Å; V83-L184 HydrophobicContact CG2-CD2 4.01Å; V83-V239 HydrophobicContact CG1-CB 4.34Å; V83-V239 HydrophobicContact CG1-CG1 4.11Å; V83-V239 HydrophobicContact CG1-CG2 4.37Å; V83-I241 HydrophobicContact CB-CD1 4.31Å; V83-I241 HydrophobicContact CG2-CD1 4.17Å
84C97.2Very high92.8Very high11 Ų1134.7 Ų34.77%0.07420%0.201CC..EExtended strand (participates in β ladder)trans-106.7138.3-179.8-73.30000111.7K71 A72 Y177 Y178K71-C84 HydrophobicContact CD-CB 4.41Å; A72-C84 WeakPolarHBondContact O-CA 3.33Å; C84-Y177 CarbonylContact O-C 3.15Å; C84-Y177 VanDerWaalsContact O-CA 3.3Å; C84-Y177 WeakPolarHBondContact O-CA 3.25Å; C84-Y178 HydrophobicContact CB-CD1 3.98Å; C84-Y178 HydrophobicContact CB-CD2 4.48Å; C84-Y178 HydrophobicContact CB-CE1 3.57Å; C84-Y178 HydrophobicContact CB-CE2 4.14Å; C84-Y178 HydrophobicContact CB-CG 4.43Å; C84-Y178 PolarHBondContact N-O 3.27Å; C84-Y178 PolarHBondContact O-N 3.46Å
85K96Very high92Very high33 Ų3334.1 Ų34.114%0.14320%0.199CC..EExtended strand (participates in β ladder)trans-102.2133.3168.4-169.6-177.280.5-177.80109K71 A72 V74 E174 F176 Y177K71-K85 CarbonylContact C-O 3.58Å; K71-K85 VanDerWaalsContact CA-O 3.27Å; K71-K85 WeakPolarHBondContact CA-O 3.12Å; A72-K85 PolarHBondContact N-O 3.01Å; A72-K85 PolarHBondContact O-N 3.22Å; V74-K85 HydrophobicContact CG2-CB 3.7Å; K85-E174 HydrophobicContact CD-CB 4.09Å; K85-E174 WeakPolarHBondContact CE-OE1 3.34Å; K85-E174 IonicContact NZ-OE1 3.92Å; K85-E174 PolarHBondContact NZ-OE1 3.09Å; K85-E174 IonicContact NZ-OE2 3.58Å; K85-E174 PolarHBondContact NZ-OE2 3.35Å; K85-F176 WeakPolarHBondContact CA-O 3.24Å; K85-Y177 HydrophobicContact CB-CD1 3.9Å; K85-Y177 HydrophobicContact CB-CE1 3.89Å; K85-Y177 HydrophobicContact CD-CE1 3.87Å; K85-Y177 HydrophobicContact CG-CD1 4.02Å; K85-Y177 HydrophobicContact CG-CE1 3.73Å; K85-Y177 HydrophobicContact CG-CE2 4.44Å
86V95.5Very high90.7Very high1 Ų139.4 Ų39.41%0.00622%0.218CC..EExtended strand (participates in β ladder)trans-74.7127.4171.5174.20000109.2I68 I89 F170 F176 Y178 M234I68-V86 HydrophobicContact CD1-CG2 4.03Å; I68-V86 HydrophobicContact CG1-CG2 4.11Å; I68-V86 HydrophobicContact CG2-CG1 4.3Å; I68-V86 HydrophobicContact CG2-CG2 3.99Å; V86-I89 HydrophobicContact CG1-CG2 3.86Å; V86-F170 HydrophobicContact CG1-CD1 4.07Å; V86-F176 HydrophobicContact CB-CB 4.48Å; V86-F176 PolarHBondContact N-O 2.84Å; V86-Y178 HydrophobicContact CG2-CD1 4.13Å; V86-Y178 HydrophobicContact CG2-CE1 3.84Å; V86-M234 HydrophobicContact CB-CE 4.45Å; V86-M234 HydrophobicContact CG2-CE 3.44Å; V86-M234 VanDerWaalsContact CG2-CE 3.44Å
87T92.6Very high89.4Confident34 Ų3441.7 Ų41.721%0.20923%0.232CC..EExtended strand (participates in β ladder)trans-111.3-30.4-179.8560000112.5Q70 A72Q70-T87 VanDerWaalsContact C-OG1 3.28Å; Q70-T87 PolarHBondContact O-N 2.85Å; Q70-T87 PolarHBondContact O-OG1 3.04Å; Q70-T87 VanDerWaalsContact O-OG1 3.09Å; A72-T87 HydrophobicContact CB-CG2 3.72Å
88K91.6Very high87.9Confident65 Ų6549.3 Ų49.328%0.28327%0.268SS..EExtended strand (participates in β ladder)trans-142.3149.3169.3-60.4-175.7-169.1153.70112R69 Q70 M171R69-K88 HydrophobicContact CB-CB 4.2Å; R69-K88 HydrophobicContact CG-CB 4.41Å; R69-K88 PolarHBondContact N-O 2.68Å; Q70-K88 HydrophobicContact CB-CB 4.16Å; Q70-K88 HydrophobicContact CB-CG 4.44Å; Q70-K88 PolarHBondContact N-O 2.86Å; Q70-K88 PolarHBondContact O-N 2.85Å; Q70-K88 VanDerWaalsContact O-N 3.1Å; Q70-K88 VanDerWaalsContact OE1-CE 3.27Å; K88-M171 HydrophobicContact CG-SD 4.3Å
89I93.2Very high86.6Confident8 Ų849.4 Ų49.44%0.04127%0.268CS..EExtended strand (participates in β ladder)trans-112.4157.5170.462.6174.7000110.6I52 I66 L67 V86 V91 L166 L167 F170I52-I89 HydrophobicContact CD1-CG2 3.49Å; I52-I89 VanDerWaalsContact CD1-CG2 3.49Å; I66-I89 HydrophobicContact CG2-CB 4.24Å; I66-I89 HydrophobicContact CG2-CD1 4.03Å; I66-I89 HydrophobicContact CG2-CG2 4.41Å; L67-I89 CarbonylContact O-C 3.41Å; L67-I89 WeakPolarHBondContact O-CA 3.45Å; L67-I89 WeakPolarHBondContact O-CB 3.39Å; V86-I89 HydrophobicContact CG1-CG2 3.86Å; I89-V91 HydrophobicContact CD1-CG2 3.74Å; I89-V91 HydrophobicContact CG1-CG2 4.14Å; I89-L166 HydrophobicContact CD1-CG 4.44Å; I89-L167 HydrophobicContact CD1-CD2 4.06Å; I89-L167 HydrophobicContact CG1-CD2 3.87Å; I89-F170 HydrophobicContact CD1-CB 4.12Å; I89-F170 HydrophobicContact CD1-CD2 3.79Å; I89-F170 HydrophobicContact CD1-CE2 4.49Å; I89-F170 HydrophobicContact CD1-CG 4.05Å; I89-F170 HydrophobicContact CG1-CB 4.33Å; I89-F170 HydrophobicContact CG2-CB 3.85Å; I89-F170 HydrophobicContact CG2-CD1 3.76Å; I89-F170 HydrophobicContact CG2-CD2 4.37Å; I89-F170 HydrophobicContact CG2-CE1 4.43Å; I89-F170 HydrophobicContact CG2-CG 3.73Å
90A91.7Very high85.4Confident6 Ų654.3 Ų54.35%0.0527%0.274CS..EExtended strand (participates in β ladder)trans-108.2142158.300000108I66 L67 R69 L104I66-A90 WeakPolarHBondContact CA-O 3.27Å; L67-A90 PolarHBondContact N-O 2.87Å; L67-A90 PolarHBondContact O-N 2.86Å; R69-A90 HydrophobicContact CB-CB 4.21Å; A90-L104 HydrophobicContact CB-CD2 4.21Å
91V90.3Very high84.1Confident30 Ų3056 Ų5618%0.18228%0.283CS..EExtended strand (participates in β ladder)trans-125117.8179.1-175.20000107.6W64 L65 I66 I89 L163 L166 L167W64-V91 HydrophobicContact CB-CG1 4.07Å; W64-V91 HydrophobicContact CD2-CG1 4.12Å; W64-V91 HydrophobicContact CE3-CG1 3.69Å; W64-V91 HydrophobicContact CG-CG1 4.34Å; W64-V91 HydrophobicContact CZ3-CG1 4.48Å; L65-V91 WeakPolarHBondContact O-CA 3.17Å; I66-V91 HydrophobicContact CG1-CG1 4.33Å; I66-V91 HydrophobicContact CG1-CG2 4.4Å; I89-V91 HydrophobicContact CD1-CG2 3.74Å; I89-V91 HydrophobicContact CG1-CG2 4.14Å; V91-L163 HydrophobicContact CB-CD1 4.11Å; V91-L163 HydrophobicContact CG1-CD1 3.99Å; V91-L163 HydrophobicContact CG2-CD1 4.1Å; V91-L166 HydrophobicContact CG2-CD2 4.47Å; V91-L167 HydrophobicContact CG2-CD2 4.32Å
92L89.3Confident83Confident0 Ų055.5 Ų55.50%028%0.282CS..EExtended strand (participates in β ladder)trans-109.7121.8-174.4-53.3179.3000109.3L3 Y10 W64 L65 L67 L94 L102L3-L92 HydrophobicContact CD1-CD1 4.33Å; L3-L92 HydrophobicContact CD2-CD1 4Å; Y10-L92 HydrophobicContact CD1-CD1 4.09Å; Y10-L92 HydrophobicContact CD2-CD1 4.41Å; Y10-L92 HydrophobicContact CE1-CD1 4.29Å; Y10-L92 HydrophobicContact CE2-CB 4.07Å; Y10-L92 HydrophobicContact CG-CD1 4.14Å; W64-L92 CarbonylContact C-O 3.53Å; W64-L92 VanDerWaalsContact CA-O 3.26Å; W64-L92 WeakPolarHBondContact CA-O 3.31Å; L65-L92 HydrophobicContact CB-CB 4.35Å; L65-L92 HydrophobicContact CD2-CD1 4.27Å; L65-L92 PolarHBondContact N-O 2.83Å; L65-L92 PolarHBondContact O-N 2.75Å; L67-L92 HydrophobicContact CD1-CD1 3.74Å; L92-L94 PolarHBondContact O-N 2.84Å; L92-L102 HydrophobicContact CD2-CD1 3.44Å; L92-L102 VanDerWaalsContact CD2-CD1 3.44Å; L92-L102 HydrophobicContact CD2-CD2 3.72Å; L92-L102 HydrophobicContact CD2-CG 4.23Å
93S86.5Confident82.1Confident35 Ų3557.1 Ų57.125%0.24529%0.289CS..EExtended strand (participates in β ladder)trans-68.7124169.2178.90000109.5Y10 S95Y10-S93 WeakPolarHBondContact CE2-O 3.47Å; Y10-S93 PolarHBondContact OH-O 3.19Å; Y10-S93 VanDerWaalsContact OH-O 3.05Å; S93-S95 PolarHBondContact O-N 3.04Å; S93-S95 PolarHBondContact OG-OG 3.24Å
94L83.5Confident81.5Confident5 Ų557.9 Ų57.93%0.02629%0.293CS..  trans-82.575.8170.3-50.9-173.2000107.8Y10 C21 R23 P62 W63 L65 L92Y10-L94 HydrophobicContact CD2-CD2 3.45Å; Y10-L94 VanDerWaalsContact CD2-CD2 3.45Å; Y10-L94 HydrophobicContact CE2-CD2 3.57Å; C21-L94 VanDerWaalsContact SG-CD1 3.55Å; R23-L94 CarbonylContact O-C 3.57Å; R23-L94 VanDerWaalsContact O-C 3.25Å; P62-L94 VanDerWaalsContact CB-O 3.29Å; P62-L94 WeakPolarHBondContact CB-O 3.23Å; W63-L94 HydrophobicContact CB-CB 4.31Å; W63-L94 HydrophobicContact CB-CD1 3.8Å; W63-L94 HydrophobicContact CB-CG 4.31Å; W63-L94 WeakPolarHBondContact O-CA 3.24Å; W63-L94 WeakPolarHBondContact O-CB 3.36Å; W63-L94 WeakPolarHBondContact O-CG 3.25Å; W63-L94 PolarHBondContact O-N 2.85Å; L65-L94 HydrophobicContact CB-CD1 4.35Å; L65-L94 HydrophobicContact CB-CD2 3.84Å; L65-L94 HydrophobicContact CB-CG 4.33Å; L92-L94 PolarHBondContact O-N 2.84Å
95S79.1Confident81Confident26 Ų2662.6 Ų62.618%0.18231%0.314CS..SBendtrans-143168.4173.862.60000110R23 S93 M97R23-S95 VanDerWaalsContact CZ-O 3.32Å; R23-S95 PolarHBondContact NE-O 3.27Å; R23-S95 PolarHBondContact NH2-O 3.49Å; R23-S95 WeakPolarHBondContact O-CA 3.45Å; R23-S95 PolarHBondContact O-N 3.42Å; S93-S95 PolarHBondContact O-N 3.04Å; S93-S95 PolarHBondContact OG-OG 3.24Å; S95-M97 PolarHBondContact O-N 3.05Å
96E68.8Low80.5Confident129 Ų12964.8 Ų64.860%0.60333%0.327SS*.SBendtrans-70.2-16.3179.1-64.2-171.8163.400113.7R23 R24R23-E96 PolarHBondContact NH2-O 3.14Å; R24-E96 IonicContact CZ-OE1 3.56Å; R24-E96 IonicContact NH1-OE1 3.68Å; R24-E96 PolarHBondContact NH1-OE1 3.36Å; R24-E96 IonicContact NH2-OE1 3.94Å; R24-E96 PolarHBondContact NH2-OE1 3.35Å
97M67.2Low80Confident134 Ų13465 Ų6566%0.6633%0.329SS*.SBendtrans-64.3149.5174.4-57.9-158-48.900111.8R23 S95R23-M97 PolarHBondContact NH2-O 2.93Å; S95-M97 PolarHBondContact O-N 3.05Å
98E64.3Low79.5Confident163 Ų16372.4 Ų72.476%0.76236%0.358SS*.PPolyproline II helixtrans-65.8143.7171.5-64.5-177.2152.800111.1
99P63.2Low79Confident32 Ų3275.9 Ų75.921%0.20837%0.373CS..PPolyproline II helixtrans-66.6142.1175.928.9-34.6000110.8Q5 L45 L102Q5-P99 VanDerWaalsContact OE1-CG 3.25Å; L45-P99 HydrophobicContact CD1-CG 4.39Å; P99-L102 HydrophobicContact CB-CD1 3.83Å; P99-L102 HydrophobicContact CB-CD2 4.47Å; P99-L102 HydrophobicContact CB-CG 4.1Å; P99-L102 HydrophobicContact CG-CD1 3.98Å
100Q62.3Low78.3Confident167 Ų16779.9 Ų79.978%0.7839%0.391SS*.PPolyproline II helixtrans-66.3147.4171.3-64.5175.31500110.1L102Q100-L102 WeakPolarHBondContact O-CD2 3.4Å; Q100-L102 VanDerWaalsContact O-CG 3.32Å; Q100-L102 WeakPolarHBondContact O-CG 3.4Å; Q100-L102 PolarHBondContact O-N 3.2Å
101D63.9Low77.6Confident153 Ų15381.4 Ų81.482%0.81840%0.397SS*.  trans-36.2101.9-169-165.5-1000114.2E103D101-E103 PolarHBondContact O-N 2.76Å
102L71.9Confident75.9Confident39 Ų3989.1 Ų89.120%0.20443%0.429CS..  trans-89.599.2-178.8-56.8172000107.6L45 L92 P99 Q100 L104L45-L102 HydrophobicContact CD1-CD1 3.84Å; L92-L102 HydrophobicContact CD2-CD1 3.44Å; L92-L102 VanDerWaalsContact CD2-CD1 3.44Å; L92-L102 HydrophobicContact CD2-CD2 3.72Å; L92-L102 HydrophobicContact CD2-CG 4.23Å; P99-L102 HydrophobicContact CB-CD1 3.83Å; P99-L102 HydrophobicContact CB-CD2 4.47Å; P99-L102 HydrophobicContact CB-CG 4.1Å; P99-L102 HydrophobicContact CG-CD1 3.98Å; Q100-L102 WeakPolarHBondContact O-CD2 3.4Å; Q100-L102 VanDerWaalsContact O-CG 3.32Å; Q100-L102 WeakPolarHBondContact O-CG 3.4Å; Q100-L102 PolarHBondContact O-N 3.2Å; L102-L104 HydrophobicContact CB-CD1 4.21Å; L102-L104 HydrophobicContact CB-CG 3.93Å; L102-L104 HydrophobicContact CD1-CD1 4.43Å; L102-L104 PolarHBondContact O-N 3.05Å
103E78.1Confident74.2Confident129 Ų12992.2 Ų92.260%0.60346%0.461SS*.  trans-63.948.8174.9-59.1178.3147.600113.7R69 D101R69-E103 VanDerWaalsContact CZ-CB 3.48Å; R69-E103 IonicContact CZ-OE2 2.72Å; R69-E103 PolarHBondContact NE-O 3.12Å; R69-E103 IonicContact NH1-OE2 2.66Å; R69-E103 PolarHBondContact NH1-OE2 2.65Å; R69-E103 PolarHBondContact NH2-O 3.37Å; R69-E103 IonicContact NH2-OE2 2.67Å; R69-E103 PolarHBondContact NH2-OE2 2.98Å; D101-E103 PolarHBondContact O-N 2.76Å
104L85.7Confident72.8Confident16 Ų1695.3 Ų95.38%0.08447%0.474CS..PPolyproline II helixtrans-75.5161.8-179.6-60.2-178.5000111.2L3 L45 V48 R69 A90 L102 L106L3-L104 HydrophobicContact CD2-CD1 3.78Å; L45-L104 HydrophobicContact CB-CD1 4.1Å; V48-L104 HydrophobicContact CG1-CD1 4.32Å; V48-L104 HydrophobicContact CG1-CD2 4.14Å; R69-L104 HydrophobicContact CB-CD2 4.45Å; R69-L104 HydrophobicContact CG-CD2 3.87Å; A90-L104 HydrophobicContact CB-CD2 4.21Å; L102-L104 HydrophobicContact CB-CD1 4.21Å; L102-L104 HydrophobicContact CB-CG 3.93Å; L102-L104 HydrophobicContact CD1-CD1 4.43Å; L102-L104 PolarHBondContact O-N 3.05Å; L104-L106 PolarHBondContact O-N 3.1Å
105E85.9Confident70.9Confident110 Ų110102.1 Ų102.151%0.51451%0.51SS..BIsolated β-bridgetrans-78.4122.9173.3-62.6-170.1-163.100109.1G46 L47 Q70 C107G46-E105 CarbonylContact C-O 3.52Å; G46-E105 WeakPolarHBondContact CA-O 2.98Å; L47-E105 WeakPolarHBondContact CB-O 3.47Å; L47-E105 WeakPolarHBondContact CG-O 3.32Å; L47-E105 PolarHBondContact N-O 3.21Å; Q70-E105 PolarHBondContact NE2-OE1 3.46Å; E105-C107 PolarHBondContact O-N 3.41Å
106L86.4Confident69Low79 Ų79109.7 Ų109.741%0.41454%0.54SS..PPolyproline II helixtrans-63.9125.2-172.4-62.3-179.8000111.3L104 K108 H111 I114L104-L106 PolarHBondContact O-N 3.1Å; L106-K108 PolarHBondContact O-N 3.06Å; L106-H111 HydrophobicContact CB-CB 3.94Å; L106-H111 HydrophobicContact CD1-CB 4.36Å; L106-I114 HydrophobicContact CD1-CB 4.41Å; L106-I114 HydrophobicContact CD1-CG2 4.03Å
107C84.2Confident67.5Low5 Ų5109 Ų1093%0.03455%0.546CS..PPolyproline II helixtrans-63.5123.6173.8179.30000111.1E2 L47 E105 K109 H110 H111E2-C107 PolarHBondContact OE1-SG 2.99Å; L47-C107 HydrophobicContact CD2-CB 3.89Å; L47-C107 HydrophobicContact CG-CB 4.22Å; E105-C107 PolarHBondContact O-N 3.41Å; C107-K109 PolarHBondContact O-N 3.44Å; C107-K109 VanDerWaalsContact O-N 3.16Å; C107-K109 PolarHBondContact SG-N 3.21Å; C107-H110 PolarHBondContact O-N 3.49Å; C107-H111 PolarHBondContact N-ND1 3.33Å; C107-H111 VanDerWaalsContact N-ND1 3.17Å; C107-H111 WeakPolarHBondContact O-CB 3.49Å; C107-H111 PolarHBondContact O-N 3Å; C107-H111 PolarHBondContact O-ND1 2.9Å
108K82.8Confident65.9Low189 Ų189111.4 Ų111.482%0.82256%0.556SS**THydrogen-bonded Turntrans-58.4-24.9179.6-63.6-177.91801790114.5L106L106-K108 PolarHBondContact O-N 3.06Å
109K81.1Confident64.5Low138 Ų138113.4 Ų113.460%0.656%0.562SS**THydrogen-bonded Turntrans-75.6-43178.3-57.8-179.6-171167.50112.3E2 C107E2-K109 IonicContact OE1-NZ 2.7Å; E2-K109 WeakPolarHBondContact OE2-CE 3.45Å; E2-K109 IonicContact OE2-NZ 3.15Å; E2-K109 PolarHBondContact OE2-NZ 3.22Å; C107-K109 PolarHBondContact O-N 3.44Å; C107-K109 VanDerWaalsContact O-N 3.16Å; C107-K109 PolarHBondContact SG-N 3.21Å
110H78.6Confident62.9Low93 Ų93119.3 Ų119.343%0.43159%0.59SS.*THydrogen-bonded Turntrans-103.7-18.7-165.7-58.1115.4000113.7E2 F4 C44 C107E2-H110 IonicContact OE1-CE1 2.7Å; E2-H110 PolarHBondContact OE1-CE1 3.17Å; E2-H110 IonicContact OE1-ND1 3.19Å; E2-H110 PolarHBondContact OE1-ND1 3.3Å; F4-H110 AromaticContact CE1-CE1 3.8Å; F4-H110 AromaticContact CE1-ND1 3.9Å; F4-H110 AromaticContact CZ-CE1 3.52Å; F4-H110 AromaticContact CZ-ND1 3.87Å; C44-H110 HydrophobicContact CB-CB 3.6Å; C107-H110 PolarHBondContact O-N 3.49Å
111H76.4Confident61.3Low37 Ų37118.4 Ų118.417%0.17159%0.589CS.*SBendtrans-109.132.8178.7-58.1104.3000112.6C44 L106 C107 G113 I114C44-H111 PolarHBondContact O-CE1 2.92Å; C44-H111 PolarHBondContact O-NE2 3.05Å; L106-H111 HydrophobicContact CB-CB 3.94Å; L106-H111 HydrophobicContact CD1-CB 4.36Å; C107-H111 PolarHBondContact N-ND1 3.33Å; C107-H111 VanDerWaalsContact N-ND1 3.17Å; C107-H111 WeakPolarHBondContact O-CB 3.49Å; C107-H111 PolarHBondContact O-N 3Å; C107-H111 PolarHBondContact O-ND1 2.9Å; H111-G113 PolarHBondContact O-N 3.01Å; H111-I114 HydrophobicContact CB-CD1 4.13Å; H111-I114 PolarHBondContact O-N 3.26Å
112F54.6Low59.7Low192 Ų192115.9 Ų115.984%0.84258%0.581SS**THydrogen-bonded Turntrans-64.1132.5-177.9-158.8-89000110.8I114F112-I114 VanDerWaalsContact C-N 3.34Å
113G53.7Low57.6Low65 Ų65116.9 Ų116.967%0.6759%0.591SS**THydrogen-bonded Turntrans86.5-12.1-175.600000115.6H111 N115H111-G113 PolarHBondContact O-N 3.01Å; G113-N115 VanDerWaalsContact C-N 3.31Å; G113-N115 PolarHBondContact O-N 2.82Å
114I57.3Low55.7Low101 Ų101116.1 Ų116.152%0.51860%0.598SS.*  trans-79.283171.9-52.1-176.7000109L106 H111 F112 K116L106-I114 HydrophobicContact CD1-CB 4.41Å; L106-I114 HydrophobicContact CD1-CG2 4.03Å; H111-I114 HydrophobicContact CB-CD1 4.13Å; H111-I114 PolarHBondContact O-N 3.26Å; F112-I114 VanDerWaalsContact C-N 3.34Å; I114-K116 PolarHBondContact O-N 3.38Å
115N43.1Very low53.2Low147 Ų147119.5 Ų119.579%0.78662%0.616SS**PPolyproline II helixtrans-59136.8166.2-79.8-23.8000109.3G113 P117G113-N115 VanDerWaalsContact C-N 3.31Å; G113-N115 PolarHBondContact O-N 2.82Å; N115-P117 WeakPolarHBondContact O-CD 3.41Å
116K39.8Very low50.7Low186 Ų186118.3 Ų118.381%0.80961%0.613SS**PPolyproline II helixtrans-55.8125.2171.7-70.9-179.6176.8174.40108.4I114 E118I114-K116 PolarHBondContact O-N 3.38Å; K116-E118 PolarHBondContact O-N 2.87Å
117P37.1Very low48.5Very low115 Ų115118.6 Ų118.675%0.74762%0.622SS**PPolyproline II helixtrans-58.6131.4156.627-31.9000107N115N115-P117 WeakPolarHBondContact O-CD 3.41Å
118E32.8Very low46.2Very low183 Ų183124.4 Ų124.486%0.85565%0.647SS**PPolyproline II helixtrans-58.3148.6169.6-66-165.2123.100109.1K116 I120K116-E118 PolarHBondContact O-N 2.87Å; E118-I120 PolarHBondContact O-N 2.89Å
119K35.2Very low43.8Very low205 Ų205122.1 Ų122.189%0.89164%0.637SS**  trans-62.895.5-172.3-70178.6177.6176.80110.9I121K119-I121 PolarHBondContact O-N 2.84Å
120I29.9Very low41.9Very low156 Ų156121.3 Ų121.380%0.864%0.638SS**  trans-58.1112.7153.5-59.6179000105.2E118 P122E118-I120 PolarHBondContact O-N 2.89Å; I120-P122 WeakPolarHBondContact O-CD 3.4Å
121I28.8Very low40Very low148 Ų148123.3 Ų123.376%0.75965%0.652SS**PPolyproline II helixtrans-64.8116.8176-59.9171.1000105.9K119 S123K119-I121 PolarHBondContact O-N 2.84Å; I121-S123 PolarHBondContact O-N 2.87Å
122P29.4Very low37.9Very low100 Ų100128.7 Ų128.765%0.64967%0.674SS**PPolyproline II helixtrans-61.5133.2179.925.1-33.2000109.2I120I120-P122 WeakPolarHBondContact O-CD 3.4Å
123S28.6Very low37Very low60 Ų60122.6 Ų122.642%0.4265%0.653SS.*PPolyproline II helixtrans-68.6145.5178.3179.60000108.9I121 D125 D126I121-S123 PolarHBondContact O-N 2.87Å; S123-D125 PolarHBondContact O-N 2.69Å; S123-D126 PolarHBondContact N-OD2 2.8Å; S123-D126 PolarHBondContact O-N 2.91Å; S123-D126 VanDerWaalsContact O-N 3.15Å
124P37.3Very low36.1Very low114 Ų114126.9 Ų126.974%0.7465%0.654SS**THydrogen-bonded Turntrans-53.8-21.8173-26.735.6000113.9S127P124-S127 PolarHBondContact O-OG 3.32Å
125D33.9Very low35Very low86 Ų86127.2 Ų127.246%0.4666%0.66SS.*THydrogen-bonded Turntrans-80.5-17.5-178.4-77.9-57000115.7S123 S127 K128S123-D125 PolarHBondContact O-N 2.69Å; D125-S127 PolarHBondContact O-N 2.86Å; D125-S127 VanDerWaalsContact O-N 3.17Å; D125-K128 WeakPolarHBondContact O-CB 3.39Å; D125-K128 PolarHBondContact O-N 3Å; D125-K128 WeakPolarHBondContact OD1-CD 3.26Å; D125-K128 VanDerWaalsContact OD1-CE 3.3Å; D125-K128 WeakPolarHBondContact OD1-CE 3.5Å; D125-K128 IonicContact OD1-NZ 3.84Å; D125-K128 PolarHBondContact OD1-NZ 3.47Å
126D33.8Very low34.5Very low85 Ų85127.4 Ų127.446%0.45566%0.656SS.*Hα-helixtrans-63.7-27.1-179.3-63.8-43.9000112S123 K128 F129S123-D126 PolarHBondContact N-OD2 2.8Å; S123-D126 PolarHBondContact O-N 2.91Å; S123-D126 VanDerWaalsContact O-N 3.15Å; D126-K128 PolarHBondContact O-N 2.81Å; D126-K128 VanDerWaalsContact O-N 3.08Å; D126-F129 PolarHBondContact O-N 2.92Å
127S39.1Very low34.5Very low86 Ų86125.2 Ų125.260%0.60165%0.652SS**Hα-helixtrans-54.6-22.3168.867.70000114.5P124 D125P124-S127 PolarHBondContact O-OG 3.32Å; D125-S127 PolarHBondContact O-N 2.86Å; D125-S127 VanDerWaalsContact O-N 3.17Å
128K36.1Very low34.5Very low127 Ų127127.3 Ų127.355%0.55265%0.649SS**Hα-helixtrans-96.1-18.8179.3-56.8170.8-172.5165.30112.9D125 D126D125-K128 WeakPolarHBondContact O-CB 3.39Å; D125-K128 PolarHBondContact O-N 3Å; D125-K128 WeakPolarHBondContact OD1-CD 3.26Å; D125-K128 VanDerWaalsContact OD1-CE 3.3Å; D125-K128 WeakPolarHBondContact OD1-CE 3.5Å; D125-K128 IonicContact OD1-NZ 3.84Å; D125-K128 PolarHBondContact OD1-NZ 3.47Å; D126-K128 PolarHBondContact O-N 2.81Å; D126-K128 VanDerWaalsContact O-N 3.08Å
129F34.2Very low34.9Very low141 Ų141122.3 Ų122.362%0.61863%0.634SS**Hα-helixtrans-78.1-49.6-179-167.9-103000111.2D126 L131 K132 T133D126-F129 PolarHBondContact O-N 2.92Å; F129-L131 PolarHBondContact O-N 2.83Å; F129-L131 VanDerWaalsContact O-N 3.14Å; F129-K132 WeakPolarHBondContact O-CB 3.26Å; F129-K132 PolarHBondContact O-N 3.31Å; F129-T133 PolarHBondContact O-N 3.15Å
130L40.6Very low35.1Very low121 Ų121119.6 Ų119.663%0.63463%0.63SS**Hα-helixtrans-57-32.7178.1-64.4175.2000112.9K132 F134L130-K132 VanDerWaalsContact C-N 3.31Å; L130-K132 PolarHBondContact O-N 2.61Å; L130-F134 PolarHBondContact O-N 2.94Å
131L37.5Very low35.4Very low135 Ų135118.8 Ų118.871%0.70763%0.632SS**Hα-helixtrans-69.3-26.1178-155.770.8000113.2F129 T135F129-L131 PolarHBondContact O-N 2.83Å; F129-L131 VanDerWaalsContact O-N 3.14Å; L131-T135 PolarHBondContact O-OG1 3.39Å; L131-T135 VanDerWaalsContact O-OG1 3.05Å
132K33.9Very low35.8Very low149 Ų149116.6 Ų116.665%0.64863%0.629SS**Hα-helixtrans-80.4-40.3176.1-70.3-178.8176.7-177.80112.3F129 L130 F134 T135F129-K132 WeakPolarHBondContact O-CB 3.26Å; F129-K132 PolarHBondContact O-N 3.31Å; L130-K132 VanDerWaalsContact C-N 3.31Å; L130-K132 PolarHBondContact O-N 2.61Å; K132-F134 VanDerWaalsContact C-N 3.3Å; K132-F134 PolarHBondContact O-N 3.44Å; K132-T135 WeakPolarHBondContact CA-OG1 3.42Å; K132-T135 PolarHBondContact O-N 3.3Å; K132-T135 VanDerWaalsContact O-N 3.13Å; K132-T135 PolarHBondContact O-OG1 3.48Å
133T35.7Very low36.6Very low65 Ų65116.9 Ų116.940%0.39964%0.64SS.*Hα-helixtrans-61.9-40.4176.2-47.90000111.4F129 T135 H136 I137F129-T133 PolarHBondContact O-N 3.15Å; T133-T135 PolarHBondContact O-N 3.17Å; T133-T135 VanDerWaalsContact O-N 3.14Å; T133-H136 PolarHBondContact O-N 3.45Å; T133-I137 HydrophobicContact CG2-CD1 4.25Å
134F33.9Very low37.4Very low155 Ų155118.3 Ų118.368%0.6865%0.648SS**Hα-helixtrans-63.1-16175.9-101.7-85.5000115.1L130 K132L130-F134 PolarHBondContact O-N 2.94Å; K132-F134 VanDerWaalsContact C-N 3.3Å; K132-F134 PolarHBondContact O-N 3.44Å
135T34.9Very low37.9Very low107 Ų107119 Ų11966%0.65665%0.646SS**Hα-helixtrans-92.7-19.7-179.615.90000114.1L131 K132 T133L131-T135 PolarHBondContact O-OG1 3.39Å; L131-T135 VanDerWaalsContact O-OG1 3.05Å; K132-T135 WeakPolarHBondContact CA-OG1 3.42Å; K132-T135 PolarHBondContact O-N 3.3Å; K132-T135 VanDerWaalsContact O-N 3.13Å; K132-T135 PolarHBondContact O-OG1 3.48Å; T133-T135 PolarHBondContact O-N 3.17Å; T133-T135 VanDerWaalsContact O-N 3.14Å
136H31.9Very low38.6Very low151 Ų151124.3 Ų124.370%0.69967%0.665SS**Hα-helixtrans-88.9-32.1-178-100.7-93.3000114.9T133 S139T133-H136 PolarHBondContact O-N 3.45Å; H136-S139 WeakPolarHBondContact O-CB 3.49Å; H136-S139 PolarHBondContact O-OG 3.29Å
137I41Very low39.4Very low140 Ų140128 Ų12872%0.71868%0.676SS**G310 helixtrans-80.5-27-166.9-61.7176.2000113.5T133 S139T133-I137 HydrophobicContact CG2-CD1 4.25Å; I137-S139 PolarHBondContact O-N 2.94Å
138K36.3Very low39.9Very low160 Ų160131.3 Ų131.370%0.69668%0.68SS**G310 helixtrans-79.832.4177.2-80.3-176174.3174.50113.5E156K138-E156 IonicContact NZ-OE1 3.31Å; K138-E156 PolarHBondContact NZ-OE1 3.33Å; K138-E156 IonicContact NZ-OE2 2.69Å; K138-E156 PolarHBondContact NZ-OE2 2.69Å
139S40.1Very low41Very low77 Ų77129.2 Ų129.254%0.53868%0.678SS.*G310 helixtrans-106.5-21.9-168.558.50000117.5H136 I137H136-S139 WeakPolarHBondContact O-CB 3.49Å; H136-S139 PolarHBondContact O-OG 3.29Å; I137-S139 PolarHBondContact O-N 2.94Å
140N39.3Very low42.2Very low148 Ų148127.6 Ų127.679%0.79167%0.671SS**SBendtrans-140.563.4-169.6-83.7-44.7000115.5
141V36.3Very low43.1Very low140 Ų140126.5 Ų126.585%0.84866%0.662SS**SBendtrans-142.2141.8153.3-179.80000108.9
142S37.6Very low44.5Very low101 Ų101123.6 Ų123.671%0.70665%0.653SS**  trans-16140.9178.761.70000119P144S142-P144 WeakPolarHBondContact O-CD 3.2Å
143A47Very low46.3Very low106 Ų106123.5 Ų123.588%0.87665%0.653SS**  trans-83.2125.3175.300000114.2
144P45.1Very low47.9Very low91 Ų91125 Ų12559%0.59166%0.655SS**  trans-112.2160.5154.738.4-33.7000112.6S142 K146 V149S142-P144 WeakPolarHBondContact O-CD 3.2Å; P144-K146 PolarHBondContact O-N 3.1Å; P144-V149 HydrophobicContact CG-CG2 4.28Å; P144-V149 WeakPolarHBondContact O-CG2 3.48Å
145N47Very low49.6Very low129 Ų129120.3 Ų120.369%0.6964%0.635SS**  trans-7.6110.1171.9-84.8-57.2000118.4K147 K148 V149N145-K147 PolarHBondContact O-N 3.2Å; N145-K148 PolarHBondContact O-N 3.15Å; N145-K148 VanDerWaalsContact O-N 3.16Å; N145-V149 PolarHBondContact O-N 3.47Å
146K50Low51.5Low196 Ų196119.3 Ų119.385%0.85262%0.623SS**Hα-helixtrans-54.3-22178.3-67.3179179.2174.80115.2P144 K150P144-K146 PolarHBondContact O-N 3.1Å; K146-K150 WeakPolarHBondContact O-CB 3.47Å
147K50.3Low53.8Low162 Ų162117.1 Ų117.170%0.70461%0.611SS**Hα-helixtrans-70.5-60.2172.4-78.8-168.6176.5-175.50112N145 V149 K150 E151N145-K147 PolarHBondContact O-N 3.2Å; K147-V149 VanDerWaalsContact C-N 3.29Å; K147-V149 PolarHBondContact O-N 3.27Å; K147-K150 WeakPolarHBondContact O-CA 3.41Å; K147-K150 WeakPolarHBondContact O-CB 3.46Å; K147-K150 PolarHBondContact O-N 3.42Å; K147-E151 PolarHBondContact O-N 2.86Å
148K49.6Very low55.5Low157 Ų157111.1 Ų111.168%0.68358%0.58SS**Hα-helixtrans-55.8-40.2-179.6-74.2-164.6172.7-169.40113.2N145 K150 E151 S152N145-K148 PolarHBondContact O-N 3.15Å; N145-K148 VanDerWaalsContact O-N 3.16Å; K148-K150 VanDerWaalsContact C-N 3.29Å; K148-K150 PolarHBondContact O-N 3.12Å; K148-E151 WeakPolarHBondContact CA-OE2 3.43Å; K148-E151 PolarHBondContact O-N 3.46Å; K148-S152 VanDerWaalsContact O-CB 3.32Å; K148-S152 WeakPolarHBondContact O-CB 3.47Å; K148-S152 PolarHBondContact O-N 3.06Å
149V58.7Low57.5Low83 Ų83105.5 Ų105.550%0.50356%0.556SS.*Hα-helixtrans-63.6-34.91771780000111.9P144 N145 K147 K153P144-V149 HydrophobicContact CG-CG2 4.28Å; P144-V149 WeakPolarHBondContact O-CG2 3.48Å; N145-V149 PolarHBondContact O-N 3.47Å; K147-V149 VanDerWaalsContact C-N 3.29Å; K147-V149 PolarHBondContact O-N 3.27Å; V149-K153 PolarHBondContact O-N 3.11Å
150K58.6Low59.6Low107 Ų107109.8 Ų109.847%0.46556%0.561SS.*Hα-helixtrans-74.4-46.2177-174.4-167.7165.6-142.40111.5K146 K147 K148 S152 K153 E154K146-K150 WeakPolarHBondContact O-CB 3.47Å; K147-K150 WeakPolarHBondContact O-CA 3.41Å; K147-K150 WeakPolarHBondContact O-CB 3.46Å; K147-K150 PolarHBondContact O-N 3.42Å; K148-K150 VanDerWaalsContact C-N 3.29Å; K148-K150 PolarHBondContact O-N 3.12Å; K150-S152 VanDerWaalsContact C-N 3.33Å; K150-S152 PolarHBondContact O-N 3.43Å; K150-K153 PolarHBondContact O-N 3.21Å; K150-K153 VanDerWaalsContact O-N 3.16Å; K150-E154 WeakPolarHBondContact CE-OE1 3.45Å; K150-E154 IonicContact NZ-OE1 3.52Å; K150-E154 IonicContact NZ-OE2 3.93Å; K150-E154 PolarHBondContact O-N 3.04Å
151E60.5Low61.7Low98 Ų98105.9 Ų105.946%0.45854%0.535SS..Hα-helixtrans-58.4-44.1177-70.8147.9-160.300111.4K147 K148 K153 E154 K155K147-E151 PolarHBondContact O-N 2.86Å; K148-E151 WeakPolarHBondContact CA-OE2 3.43Å; K148-E151 PolarHBondContact O-N 3.46Å; E151-K153 PolarHBondContact O-N 2.93Å; E151-E154 PolarHBondContact O-N 3.25Å; E151-K155 PolarHBondContact O-N 2.56Å
152S66.4Low64Low74 Ų7499.4 Ų99.452%0.51750%0.495SS..Hα-helixtrans-57.8-45.2173.5170.90000112.4K148 K150 E154 K155 E156K148-S152 VanDerWaalsContact O-CB 3.32Å; K148-S152 WeakPolarHBondContact O-CB 3.47Å; K148-S152 PolarHBondContact O-N 3.06Å; K150-S152 VanDerWaalsContact C-N 3.33Å; K150-S152 PolarHBondContact O-N 3.43Å; S152-E154 VanDerWaalsContact C-N 3.33Å; S152-E154 PolarHBondContact O-N 2.88Å; S152-K155 PolarHBondContact O-N 3.01Å; S152-E156 WeakPolarHBondContact O-CB 3.33Å; S152-E156 PolarHBondContact O-N 3.12Å
153K72.9Confident66.3Low147 Ų14796.8 Ų96.864%0.63947%0.473SS*.Hα-helixtrans-69.2-28.8177.8-172172.3-177.8173.90113.3V149 K150 E151 K157V149-K153 PolarHBondContact O-N 3.11Å; K150-K153 PolarHBondContact O-N 3.21Å; K150-K153 VanDerWaalsContact O-N 3.16Å; E151-K153 PolarHBondContact O-N 2.93Å; K153-K157 WeakPolarHBondContact O-CB 3.43Å; K153-K157 PolarHBondContact O-N 3.09Å
154E68.6Low68.2Low96 Ų9695.3 Ų95.345%0.44945%0.448SS..Hα-helixtrans-75.2-35174-72.8174.5161.700111K150 E151 S152 K157 L158K150-E154 WeakPolarHBondContact CE-OE1 3.45Å; K150-E154 IonicContact NZ-OE1 3.52Å; K150-E154 IonicContact NZ-OE2 3.93Å; K150-E154 PolarHBondContact O-N 3.04Å; E151-E154 PolarHBondContact O-N 3.25Å; S152-E154 VanDerWaalsContact C-N 3.33Å; S152-E154 PolarHBondContact O-N 2.88Å; E154-K157 PolarHBondContact O-N 2.88Å; E154-L158 PolarHBondContact O-N 3.23Å; E154-L158 VanDerWaalsContact O-N 3.1Å
155K70.4Confident70.2Confident57 Ų5791.7 Ų91.725%0.24842%0.423CS..Hα-helixtrans-63.4-50.7167.6-75.9-177.9173.2177.80112.7D60 E151 S152 K157 L158 E159 Y575D60-K155 IonicContact OD2-NZ 2.7Å; D60-K155 PolarHBondContact OD2-NZ 2.75Å; E151-K155 PolarHBondContact O-N 2.56Å; S152-K155 PolarHBondContact O-N 3.01Å; K155-K157 PolarHBondContact O-N 2.82Å; K155-L158 PolarHBondContact O-N 3.01Å; K155-E159 WeakPolarHBondContact O-CB 2.97Å; K155-E159 PolarHBondContact O-N 3.35Å; K155-Y575 WeakPolarHBondContact CE-OH 3.23Å
156E74.8Confident72.2Confident86 Ų8685.7 Ų85.740%0.40239%0.391SS..Hα-helixtrans-52.2-38.1175.5-175-177.9-170.800111.5K138 S152 R160K138-E156 IonicContact NZ-OE1 3.31Å; K138-E156 PolarHBondContact NZ-OE1 3.33Å; K138-E156 IonicContact NZ-OE2 2.69Å; K138-E156 PolarHBondContact NZ-OE2 2.69Å; S152-E156 WeakPolarHBondContact O-CB 3.33Å; S152-E156 PolarHBondContact O-N 3.12Å; E156-R160 WeakPolarHBondContact O-CB 3.4Å; E156-R160 PolarHBondContact O-N 2.74Å
157K78.6Confident74.1Confident105 Ų10578.6 Ų78.646%0.45736%0.362SS..Hα-helixtrans-73.7-36.5176.8-172.6-172.2176-166.30113.5K153 E154 K155 R161K153-K157 WeakPolarHBondContact O-CB 3.43Å; K153-K157 PolarHBondContact O-N 3.09Å; E154-K157 PolarHBondContact O-N 2.88Å; K155-K157 PolarHBondContact O-N 2.82Å; K157-R161 WeakPolarHBondContact O-CG 3.47Å; K157-R161 PolarHBondContact O-N 2.83Å; K157-R161 VanDerWaalsContact O-N 3.13Å
158L77.6Confident75.9Confident13 Ų1373 Ų737%0.06834%0.338CS..Hα-helixtrans-68.8-49.9175.9170.556.3000111E154 K155 R160 R161 L162 Y557 L574 F578E154-L158 PolarHBondContact O-N 3.23Å; E154-L158 VanDerWaalsContact O-N 3.1Å; K155-L158 PolarHBondContact O-N 3.01Å; L158-R160 VanDerWaalsContact C-N 3.29Å; L158-R160 PolarHBondContact O-N 3.32Å; L158-R161 WeakPolarHBondContact O-CA 3.37Å; L158-R161 WeakPolarHBondContact O-CB 3.45Å; L158-R161 PolarHBondContact O-N 3.3Å; L158-L162 HydrophobicContact CD1-CD1 3.79Å; L158-L162 HydrophobicContact CD1-CD2 4.36Å; L158-L162 HydrophobicContact CD1-CG 3.81Å; L158-L162 HydrophobicContact CG-CD1 3.99Å; L158-L162 HydrophobicContact CG-CG 4.43Å; L158-L162 WeakPolarHBondContact O-CG 3.4Å; L158-L162 PolarHBondContact O-N 2.73Å; L158-Y557 HydrophobicContact CD1-CD1 4.44Å; L158-Y557 HydrophobicContact CD1-CE1 4.22Å; L158-L574 HydrophobicContact CD1-CD1 4.29Å; L158-L574 HydrophobicContact CD1-CD2 3.8Å; L158-L574 HydrophobicContact CD2-CD1 4.3Å; L158-F578 HydrophobicContact CB-CE2 3.84Å; L158-F578 HydrophobicContact CB-CZ 3.85Å; L158-F578 HydrophobicContact CD1-CE2 3.82Å; L158-F578 HydrophobicContact CD1-CZ 4.11Å; L158-F578 HydrophobicContact CD2-CE2 4.13Å; L158-F578 HydrophobicContact CG-CE2 4.12Å; L158-F578 HydrophobicContact CG-CZ 4.46Å
159E79.3Confident77.7Confident42 Ų4265.7 Ų65.720%0.19631%0.306CS..Hα-helixtrans-49.5-50175.9173.7169.9-139.500111.2L57 L61 W64 K155 R161 L162 L163L57-E159 HydrophobicContact CD1-CB 4.3Å; L57-E159 HydrophobicContact CD1-CG 3.97Å; L61-E159 HydrophobicContact CD1-CB 4.34Å; W64-E159 HydrophobicContact CH2-CG 3.67Å; W64-E159 HydrophobicContact CZ2-CG 3.43Å; W64-E159 VanDerWaalsContact CZ2-CG 3.43Å; W64-E159 WeakPolarHBondContact CZ2-OE1 3.2Å; K155-E159 WeakPolarHBondContact O-CB 2.97Å; K155-E159 PolarHBondContact O-N 3.35Å; E159-R161 PolarHBondContact O-N 3.21Å; E159-L162 PolarHBondContact O-N 3.38Å; E159-L163 PolarHBondContact O-N 2.72Å
160R82.8Confident79.1Confident168 Ų16861.8 Ų61.863%0.63428%0.283SS*.Hα-helixtrans-60.8-43.8173.7-178.3175.2174142.47.8113.6E156 L158 L162 L163 E164E156-R160 WeakPolarHBondContact O-CB 3.4Å; E156-R160 PolarHBondContact O-N 2.74Å; L158-R160 VanDerWaalsContact C-N 3.29Å; L158-R160 PolarHBondContact O-N 3.32Å; R160-L162 VanDerWaalsContact C-N 3.31Å; R160-L162 PolarHBondContact O-N 2.83Å; R160-L163 PolarHBondContact O-N 3.03Å; R160-E164 HydrophobicContact CG-CG 4.41Å; R160-E164 WeakPolarHBondContact CG-OE1 3.4Å; R160-E164 IonicContact CZ-OE1 2.73Å; R160-E164 IonicContact NE-OE1 2.68Å; R160-E164 PolarHBondContact NE-OE1 3Å; R160-E164 IonicContact NH2-OE1 3.7Å; R160-E164 PolarHBondContact NH2-OE1 3.4Å; R160-E164 WeakPolarHBondContact O-CB 3.26Å; R160-E164 WeakPolarHBondContact O-CG 3.31Å; R160-E164 PolarHBondContact O-N 2.78Å
161R83.6Confident80.2Confident66 Ų6659.8 Ų59.825%0.24928%0.276CS..Hα-helixtrans-61.9-37.8177.4-82.3178.4163.8-173.9-9.2111.8K157 L158 E159 E165 Y557 E581K157-R161 WeakPolarHBondContact O-CG 3.47Å; K157-R161 PolarHBondContact O-N 2.83Å; K157-R161 VanDerWaalsContact O-N 3.13Å; L158-R161 WeakPolarHBondContact O-CA 3.37Å; L158-R161 WeakPolarHBondContact O-CB 3.45Å; L158-R161 PolarHBondContact O-N 3.3Å; E159-R161 PolarHBondContact O-N 3.21Å; R161-E165 PolarHBondContact O-N 3.26Å; R161-Y557 HydrophobicContact CB-CD1 4.12Å; R161-Y557 HydrophobicContact CB-CE1 4.19Å; R161-Y557 PolarHBondContact NH1-OH 2.74Å; R161-E581 IonicContact CZ-OE2 3.27Å; R161-E581 IonicContact NH1-OE1 2.77Å; R161-E581 IonicContact NH1-OE2 2.64Å; R161-E581 PolarHBondContact NH1-OE2 2.83Å; R161-E581 IonicContact NH2-OE1 3.33Å; R161-E581 IonicContact NH2-OE2 2.83Å
162L85.2Confident81Confident3 Ų360 Ų602%0.01628%0.28CS..Hα-helixtrans-71.2-44.1177.2-66.9172.5000111.7L57 L158 E159 R160 E164 E165 L166 Y557 A560 V561 L564 L574L57-L162 HydrophobicContact CB-CD1 4.36Å; L57-L162 HydrophobicContact CD1-CB 4.24Å; L57-L162 HydrophobicContact CD1-CD1 4.26Å; L57-L162 HydrophobicContact CD2-CB 4.37Å; L57-L162 HydrophobicContact CD2-CD1 4.3Å; L158-L162 HydrophobicContact CD1-CD1 3.79Å; L158-L162 HydrophobicContact CD1-CD2 4.36Å; L158-L162 HydrophobicContact CD1-CG 3.81Å; L158-L162 HydrophobicContact CG-CD1 3.99Å; L158-L162 HydrophobicContact CG-CG 4.43Å; L158-L162 WeakPolarHBondContact O-CG 3.4Å; L158-L162 PolarHBondContact O-N 2.73Å; E159-L162 PolarHBondContact O-N 3.38Å; R160-L162 VanDerWaalsContact C-N 3.31Å; R160-L162 PolarHBondContact O-N 2.83Å; L162-E164 VanDerWaalsContact C-N 3.33Å; L162-E164 PolarHBondContact O-N 3.33Å; L162-E165 PolarHBondContact O-N 2.85Å; L162-L166 WeakPolarHBondContact O-CB 3.44Å; L162-L166 PolarHBondContact O-N 2.84Å; L162-Y557 HydrophobicContact CD2-CD1 4.45Å; L162-A560 HydrophobicContact CD2-CB 3.9Å; L162-V561 HydrophobicContact CB-CG2 4.32Å; L162-V561 HydrophobicContact CD2-CG2 3.9Å; L162-L564 HydrophobicContact CD1-CD1 4.22Å; L162-L574 HydrophobicContact CD1-CD1 4.22Å
163L85.6Confident81.3Confident46 Ų4656.7 Ų56.724%0.24126%0.257CS..Hα-helixtrans-56.7-47.6172.1-17852.5000111.8W64 V91 E159 R160 E165 L166 L167W64-L163 HydrophobicContact CE3-CD1 4.24Å; W64-L163 HydrophobicContact CH2-CB 3.67Å; W64-L163 HydrophobicContact CH2-CD1 4.31Å; W64-L163 HydrophobicContact CH2-CD2 4.01Å; W64-L163 HydrophobicContact CH2-CG 4.2Å; W64-L163 HydrophobicContact CZ3-CB 3.58Å; W64-L163 HydrophobicContact CZ3-CD1 3.65Å; W64-L163 HydrophobicContact CZ3-CD2 4.19Å; W64-L163 HydrophobicContact CZ3-CG 3.98Å; V91-L163 HydrophobicContact CB-CD1 4.11Å; V91-L163 HydrophobicContact CG1-CD1 3.99Å; V91-L163 HydrophobicContact CG2-CD1 4.1Å; E159-L163 PolarHBondContact O-N 2.72Å; R160-L163 PolarHBondContact O-N 3.03Å; L163-E165 VanDerWaalsContact C-N 3.28Å; L163-E165 PolarHBondContact O-N 3.48Å; L163-L166 PolarHBondContact O-N 3.32Å; L163-L167 HydrophobicContact CD1-CD1 3.88Å; L163-L167 HydrophobicContact CD1-CG 4Å; L163-L167 HydrophobicContact CG-CD1 3.86Å; L163-L167 HydrophobicContact CG-CG 4.43Å; L163-L167 WeakPolarHBondContact O-CB 3.41Å; L163-L167 VanDerWaalsContact O-CG 3.32Å; L163-L167 WeakPolarHBondContact O-CG 3.43Å; L163-L167 PolarHBondContact O-N 3.15Å
164E87.3Confident81.7Confident75 Ų7553.6 Ų53.635%0.3525%0.245SC..Hα-helixtrans-60.9-35.6-179.6-78.6-179.3-160.800111.7R160 L162 K168R160-E164 HydrophobicContact CG-CG 4.41Å; R160-E164 WeakPolarHBondContact CG-OE1 3.4Å; R160-E164 IonicContact CZ-OE1 2.73Å; R160-E164 IonicContact NE-OE1 2.68Å; R160-E164 PolarHBondContact NE-OE1 3Å; R160-E164 IonicContact NH2-OE1 3.7Å; R160-E164 PolarHBondContact NH2-OE1 3.4Å; R160-E164 WeakPolarHBondContact O-CB 3.26Å; R160-E164 WeakPolarHBondContact O-CG 3.31Å; R160-E164 PolarHBondContact O-N 2.78Å; L162-E164 VanDerWaalsContact C-N 3.33Å; L162-E164 PolarHBondContact O-N 3.33Å; E164-K168 VanDerWaalsContact C-NZ 3.27Å; E164-K168 VanDerWaalsContact O-CG 3.29Å; E164-K168 WeakPolarHBondContact O-CG 3.49Å; E164-K168 PolarHBondContact O-N 3.32Å; E164-K168 PolarHBondContact O-NZ 3.42Å
165E87.3Confident82.7Confident15 Ų1549 Ų497%0.0722%0.224CC..Hα-helixtrans-84.4-29.8176.3-65.7-61.1129.300113.6R161 L162 L163 K168 M169 K554 V561R161-E165 PolarHBondContact O-N 3.26Å; L162-E165 PolarHBondContact O-N 2.85Å; L163-E165 VanDerWaalsContact C-N 3.28Å; L163-E165 PolarHBondContact O-N 3.48Å; E165-K168 PolarHBondContact O-N 2.88Å; E165-K168 WeakPolarHBondContact OE1-CE 3.43Å; E165-K168 IonicContact OE1-NZ 3.76Å; E165-K168 PolarHBondContact OE1-NZ 2.87Å; E165-M169 WeakPolarHBondContact O-CG 3.27Å; E165-M169 PolarHBondContact O-N 3.46Å; E165-K554 IonicContact OE1-NZ 3.74Å; E165-K554 PolarHBondContact OE1-NZ 3.25Å; E165-V561 HydrophobicContact CB-CG2 4.45Å
166L89.3Confident83.9Confident3 Ų346.4 Ų46.42%0.01621%0.212CC..Hα-helixtrans-58.8-47.9168.6175.568.3000111.3I66 I89 V91 L162 L163 K168 M169 F170 V561 M565I66-L166 HydrophobicContact CD1-CD1 4.42Å; I66-L166 HydrophobicContact CD1-CD2 3.82Å; I89-L166 HydrophobicContact CD1-CG 4.44Å; V91-L166 HydrophobicContact CG2-CD2 4.47Å; L162-L166 WeakPolarHBondContact O-CB 3.44Å; L162-L166 PolarHBondContact O-N 2.84Å; L163-L166 PolarHBondContact O-N 3.32Å; L166-K168 VanDerWaalsContact C-N 3.32Å; L166-K168 PolarHBondContact O-N 3.43Å; L166-M169 WeakPolarHBondContact O-CB 3.27Å; L166-M169 PolarHBondContact O-N 3.22Å; L166-M169 VanDerWaalsContact O-N 3.11Å; L166-F170 HydrophobicContact CD1-CD2 4.17Å; L166-F170 HydrophobicContact CD1-CE2 3.87Å; L166-F170 PolarHBondContact O-N 3.15Å; L166-V561 HydrophobicContact CB-CG1 3.9Å; L166-V561 HydrophobicContact CB-CG2 4.46Å; L166-V561 HydrophobicContact CD1-CG1 3.73Å; L166-V561 HydrophobicContact CG-CG1 4.43Å; L166-M565 HydrophobicContact CD1-SD 4.05Å
167L88.6Confident85Confident47 Ų4742.8 Ų42.825%0.24620%0.195CC..Hα-helixtrans-58.4-42.3175.7-74.6168.2000111.7I89 V91 L163 M169 F170 M171I89-L167 HydrophobicContact CD1-CD2 4.06Å; I89-L167 HydrophobicContact CG1-CD2 3.87Å; V91-L167 HydrophobicContact CG2-CD2 4.32Å; L163-L167 HydrophobicContact CD1-CD1 3.88Å; L163-L167 HydrophobicContact CD1-CG 4Å; L163-L167 HydrophobicContact CG-CD1 3.86Å; L163-L167 HydrophobicContact CG-CG 4.43Å; L163-L167 WeakPolarHBondContact O-CB 3.41Å; L163-L167 VanDerWaalsContact O-CG 3.32Å; L163-L167 WeakPolarHBondContact O-CG 3.43Å; L163-L167 PolarHBondContact O-N 3.15Å; L167-M169 PolarHBondContact O-N 2.87Å; L167-F170 PolarHBondContact O-N 3.41Å; L167-M171 HydrophobicContact CB-CE 4Å; L167-M171 HydrophobicContact CD2-CE 4.43Å; L167-M171 WeakPolarHBondContact O-CB 3.42Å; L167-M171 WeakPolarHBondContact O-CG 3.43Å; L167-M171 PolarHBondContact O-N 3.38Å
168K87.6Confident85.9Confident44 Ų4437.9 Ų37.919%0.19117%0.174CC..Hα-helixtrans-71-25.7175.6-64.5-176.8-154.379.40113.9E164 E165 L166 F170 D172 S173E164-K168 VanDerWaalsContact C-NZ 3.27Å; E164-K168 VanDerWaalsContact O-CG 3.29Å; E164-K168 WeakPolarHBondContact O-CG 3.49Å; E164-K168 PolarHBondContact O-N 3.32Å; E164-K168 PolarHBondContact O-NZ 3.42Å; E165-K168 PolarHBondContact O-N 2.88Å; E165-K168 WeakPolarHBondContact OE1-CE 3.43Å; E165-K168 IonicContact OE1-NZ 3.76Å; E165-K168 PolarHBondContact OE1-NZ 2.87Å; L166-K168 VanDerWaalsContact C-N 3.32Å; L166-K168 PolarHBondContact O-N 3.43Å; K168-F170 VanDerWaalsContact C-N 3.34Å; K168-D172 HydrophobicContact CB-CB 4.21Å; K168-D172 VanDerWaalsContact CG-OD2 3.28Å; K168-D172 WeakPolarHBondContact CG-OD2 3.42Å; K168-D172 WeakPolarHBondContact O-CB 3.45Å; K168-D172 PolarHBondContact O-N 3.43Å; K168-S173 PolarHBondContact O-N 2.85Å; K168-S173 VanDerWaalsContact O-N 3.15Å; K168-S173 PolarHBondContact O-OG 3.43Å
169M87.4Confident86.8Confident4 Ų437.4 Ų37.42%0.0217%0.172CC..Hα-helixtrans-68.8-33.4174.5-84178.152.700112.2E165 L166 L167 S173 F176 R558 V561 I562 M565E165-M169 WeakPolarHBondContact O-CG 3.27Å; E165-M169 PolarHBondContact O-N 3.46Å; L166-M169 WeakPolarHBondContact O-CB 3.27Å; L166-M169 PolarHBondContact O-N 3.22Å; L166-M169 VanDerWaalsContact O-N 3.11Å; L167-M169 PolarHBondContact O-N 2.87Å; M169-S173 WeakPolarHBondContact O-CB 3.32Å; M169-F176 WeakPolarHBondContact O-CE2 3.32Å; M169-R558 HydrophobicContact CG-CG 4.13Å; M169-R558 HydrophobicContact SD-CG 3.83Å; M169-V561 HydrophobicContact CE-CG1 4.09Å; M169-V561 HydrophobicContact SD-CB 3.91Å; M169-V561 HydrophobicContact SD-CG1 3.56Å; M169-V561 VanDerWaalsContact SD-CG1 3.56Å; M169-I562 HydrophobicContact CE-CG1 3.61Å; M169-I562 HydrophobicContact SD-CG1 4.1Å; M169-M565 HydrophobicContact CE-SD 3.69Å
170F88.1Confident87.4Confident1 Ų141 Ų410%0.00419%0.191CC..Hα-helixtrans-87.8-47.4174.5-76.8-89.2000113I52 V86 I89 L166 L167 K168 F176 M565I52-F170 HydrophobicContact CD1-CD1 4.1Å; I52-F170 HydrophobicContact CD1-CE1 3.64Å; I52-F170 HydrophobicContact CD1-CZ 4.14Å; I52-F170 HydrophobicContact CG2-CE1 4.3Å; I52-F170 HydrophobicContact CG2-CZ 4.01Å; V86-F170 HydrophobicContact CG1-CD1 4.07Å; I89-F170 HydrophobicContact CD1-CB 4.12Å; I89-F170 HydrophobicContact CD1-CD2 3.79Å; I89-F170 HydrophobicContact CD1-CE2 4.49Å; I89-F170 HydrophobicContact CD1-CG 4.05Å; I89-F170 HydrophobicContact CG1-CB 4.33Å; I89-F170 HydrophobicContact CG2-CB 3.85Å; I89-F170 HydrophobicContact CG2-CD1 3.76Å; I89-F170 HydrophobicContact CG2-CD2 4.37Å; I89-F170 HydrophobicContact CG2-CE1 4.43Å; I89-F170 HydrophobicContact CG2-CG 3.73Å; L166-F170 HydrophobicContact CD1-CD2 4.17Å; L166-F170 HydrophobicContact CD1-CE2 3.87Å; L166-F170 PolarHBondContact O-N 3.15Å; L167-F170 PolarHBondContact O-N 3.41Å; K168-F170 VanDerWaalsContact C-N 3.34Å; F170-F176 HydrophobicContact CD1-CB 4.22Å; F170-F176 AromaticContact CD1-CD2 3.28Å; F170-F176 HydrophobicContact CD1-CD2 3.28Å; F170-F176 AromaticContact CD1-CE2 3.68Å; F170-F176 HydrophobicContact CD1-CE2 3.68Å; F170-F176 AromaticContact CD1-CG 3.88Å; F170-F176 HydrophobicContact CD1-CG 3.88Å; F170-F176 HydrophobicContact CD2-CD2 4.41Å; F170-F176 AromaticContact CD2-CE2 3.98Å; F170-F176 HydrophobicContact CD2-CE2 3.98Å; F170-F176 HydrophobicContact CE1-CB 4.1Å; F170-F176 HydrophobicContact CE1-CD1 4.08Å; F170-F176 AromaticContact CE1-CD2 3.34Å; F170-F176 HydrophobicContact CE1-CD2 3.34Å; F170-F176 HydrophobicContact CE1-CE1 4.27Å; F170-F176 AromaticContact CE1-CE2 3.56Å; F170-F176 HydrophobicContact CE1-CE2 3.56Å; F170-F176 AromaticContact CE1-CG 3.58Å; F170-F176 HydrophobicContact CE1-CG 3.58Å; F170-F176 HydrophobicContact CE1-CZ 4.01Å; F170-F176 HydrophobicContact CE2-CD2 4.46Å; F170-F176 AromaticContact CE2-CE2 3.88Å; F170-F176 HydrophobicContact CE2-CE2 3.88Å; F170-F176 HydrophobicContact CE2-CZ 4.15Å; F170-F176 AromaticContact CG-CD2 3.86Å; F170-F176 HydrophobicContact CG-CD2 3.86Å; F170-F176 AromaticContact CG-CE2 3.89Å; F170-F176 HydrophobicContact CG-CE2 3.89Å; F170-F176 HydrophobicContact CZ-CD1 4.48Å; F170-F176 AromaticContact CZ-CD2 3.97Å; F170-F176 HydrophobicContact CZ-CD2 3.97Å; F170-F176 HydrophobicContact CZ-CE1 4.24Å; F170-F176 AromaticContact CZ-CE2 3.68Å; F170-F176 HydrophobicContact CZ-CE2 3.68Å; F170-F176 HydrophobicContact CZ-CG 4.33Å; F170-F176 AromaticContact CZ-CZ 3.8Å; F170-F176 HydrophobicContact CZ-CZ 3.8Å; F170-M565 HydrophobicContact CE2-CE 3.68Å; F170-M565 HydrophobicContact CE2-SD 4.27Å; F170-M565 HydrophobicContact CZ-CE 3.59Å
171M83.3Confident87.9Confident65 Ų6537.1 Ų37.132%0.3219%0.187SC..THydrogen-bonded Turntrans-81.4-70.7-174-56.5-173-50.700112.2K88 L167 S173 E174K88-M171 HydrophobicContact CG-SD 4.3Å; L167-M171 HydrophobicContact CB-CE 4Å; L167-M171 HydrophobicContact CD2-CE 4.43Å; L167-M171 WeakPolarHBondContact O-CB 3.42Å; L167-M171 WeakPolarHBondContact O-CG 3.43Å; L167-M171 PolarHBondContact O-N 3.38Å; M171-S173 PolarHBondContact O-N 2.92Å; M171-S173 VanDerWaalsContact O-N 3.12Å; M171-E174 WeakPolarHBondContact O-CG 3.39Å; M171-E174 PolarHBondContact O-N 2.87Å
172D75.9Confident88.4Confident103 Ų10335 Ų3555%0.55118%0.179SC*.THydrogen-bonded Turntrans-60.8-27-174.5-5519.3000113.9K168K168-D172 HydrophobicContact CB-CB 4.21Å; K168-D172 VanDerWaalsContact CG-OD2 3.28Å; K168-D172 WeakPolarHBondContact CG-OD2 3.42Å; K168-D172 WeakPolarHBondContact O-CB 3.45Å; K168-D172 PolarHBondContact O-N 3.43Å
173S72.5Confident88.8Confident5 Ų535.2 Ų35.24%0.03518%0.18CC..THydrogen-bonded Turntrans-93.5-17.2-175-45.50000113.1K168 M169 M171 S175 R558K168-S173 PolarHBondContact O-N 2.85Å; K168-S173 VanDerWaalsContact O-N 3.15Å; K168-S173 PolarHBondContact O-OG 3.43Å; M169-S173 WeakPolarHBondContact O-CB 3.32Å; M171-S173 PolarHBondContact O-N 2.92Å; M171-S173 VanDerWaalsContact O-N 3.12Å; S173-S175 VanDerWaalsContact CB-OG 3.31Å; S173-S175 WeakPolarHBondContact CB-OG 3.29Å; S173-S175 PolarHBondContact O-N 3.5Å; S173-S175 PolarHBondContact O-OG 3.16Å; S173-R558 PolarHBondContact OG-NH1 3.06Å; S173-R558 PolarHBondContact OG-NH2 3.41Å
174E81.8Confident89.4Confident81 Ų8133.3 Ų33.338%0.37917%0.17SC..  trans44.435.8-177.3-59.8-157.2120.100114.8K85 M171K85-E174 HydrophobicContact CD-CB 4.09Å; K85-E174 WeakPolarHBondContact CE-OE1 3.34Å; K85-E174 IonicContact NZ-OE1 3.92Å; K85-E174 PolarHBondContact NZ-OE1 3.09Å; K85-E174 IonicContact NZ-OE2 3.58Å; K85-E174 PolarHBondContact NZ-OE2 3.35Å; M171-E174 WeakPolarHBondContact O-CG 3.39Å; M171-E174 PolarHBondContact O-N 2.87Å
175S89.8Confident89.8Confident1 Ų129.8 Ų29.81%0.00715%0.153CC..  trans-97.53.3-157.3-70.40000115.9S173 Q236 G237 Q515S173-S175 VanDerWaalsContact CB-OG 3.31Å; S173-S175 WeakPolarHBondContact CB-OG 3.29Å; S173-S175 PolarHBondContact O-N 3.5Å; S173-S175 PolarHBondContact O-OG 3.16Å; S175-Q236 CarbonylContact O-C 3.57Å; S175-Q236 WeakPolarHBondContact O-CA 3.46Å; S175-G237 PolarHBondContact O-N 3.01Å; S175-Q515 WeakPolarHBondContact OG-CG 3.29Å; S175-Q515 PolarHBondContact OG-NE2 3.43Å
176F96.2Very high90.3Very high2 Ų229.9 Ų29.91%0.00915%0.154CC..EExtended strand (participates in β ladder)trans-122.9127.6-168.5-68.3-78.8000112.3K85 V86 M169 F170 W211 M234 I235 Q236 M565K85-F176 WeakPolarHBondContact CA-O 3.24Å; V86-F176 HydrophobicContact CB-CB 4.48Å; V86-F176 PolarHBondContact N-O 2.84Å; M169-F176 WeakPolarHBondContact O-CE2 3.32Å; F170-F176 HydrophobicContact CD1-CB 4.22Å; F170-F176 AromaticContact CD1-CD2 3.28Å; F170-F176 HydrophobicContact CD1-CD2 3.28Å; F170-F176 AromaticContact CD1-CE2 3.68Å; F170-F176 HydrophobicContact CD1-CE2 3.68Å; F170-F176 AromaticContact CD1-CG 3.88Å; F170-F176 HydrophobicContact CD1-CG 3.88Å; F170-F176 HydrophobicContact CD2-CD2 4.41Å; F170-F176 AromaticContact CD2-CE2 3.98Å; F170-F176 HydrophobicContact CD2-CE2 3.98Å; F170-F176 HydrophobicContact CE1-CB 4.1Å; F170-F176 HydrophobicContact CE1-CD1 4.08Å; F170-F176 AromaticContact CE1-CD2 3.34Å; F170-F176 HydrophobicContact CE1-CD2 3.34Å; F170-F176 HydrophobicContact CE1-CE1 4.27Å; F170-F176 AromaticContact CE1-CE2 3.56Å; F170-F176 HydrophobicContact CE1-CE2 3.56Å; F170-F176 AromaticContact CE1-CG 3.58Å; F170-F176 HydrophobicContact CE1-CG 3.58Å; F170-F176 HydrophobicContact CE1-CZ 4.01Å; F170-F176 HydrophobicContact CE2-CD2 4.46Å; F170-F176 AromaticContact CE2-CE2 3.88Å; F170-F176 HydrophobicContact CE2-CE2 3.88Å; F170-F176 HydrophobicContact CE2-CZ 4.15Å; F170-F176 AromaticContact CG-CD2 3.86Å; F170-F176 HydrophobicContact CG-CD2 3.86Å; F170-F176 AromaticContact CG-CE2 3.89Å; F170-F176 HydrophobicContact CG-CE2 3.89Å; F170-F176 HydrophobicContact CZ-CD1 4.48Å; F170-F176 AromaticContact CZ-CD2 3.97Å; F170-F176 HydrophobicContact CZ-CD2 3.97Å; F170-F176 HydrophobicContact CZ-CE1 4.24Å; F170-F176 AromaticContact CZ-CE2 3.68Å; F170-F176 HydrophobicContact CZ-CE2 3.68Å; F170-F176 HydrophobicContact CZ-CG 4.33Å; F170-F176 AromaticContact CZ-CZ 3.8Å; F170-F176 HydrophobicContact CZ-CZ 3.8Å; F176-W211 AromaticContact CE1-CD1 3.58Å; F176-W211 HydrophobicContact CE1-CD2 4.5Å; F176-W211 HydrophobicContact CE1-CG 4.03Å; F176-W211 AromaticContact CE1-NE1 3.75Å; F176-M234 HydrophobicContact CB-CE 4.08Å; F176-I235 WeakPolarHBondContact CA-O 3.25Å; F176-Q236 HydrophobicContact CD1-CB 4.03Å; F176-Q236 HydrophobicContact CD1-CG 4.29Å; F176-Q236 HydrophobicContact CE1-CB 3.82Å; F176-Q236 HydrophobicContact CE1-CG 3.98Å; F176-Q236 VanDerWaalsContact CE1-NE2 3.33Å; F176-Q236 HydrophobicContact CZ-CG 4.36Å; F176-M565 HydrophobicContact CE1-CE 4.28Å; F176-M565 HydrophobicContact CZ-CE 3.91Å
177Y97.9Very high90.6Very high9 Ų930 Ų304%0.03516%0.155CC..EExtended strand (participates in β ladder)trans-133.9146.8-171.7-60.4-103.3000111V74 C84 K85 M234 I235 V239V74-Y177 HydrophobicContact CG2-CD1 3.87Å; V74-Y177 HydrophobicContact CG2-CE1 3.78Å; C84-Y177 CarbonylContact O-C 3.15Å; C84-Y177 VanDerWaalsContact O-CA 3.3Å; C84-Y177 WeakPolarHBondContact O-CA 3.25Å; K85-Y177 HydrophobicContact CB-CD1 3.9Å; K85-Y177 HydrophobicContact CB-CE1 3.89Å; K85-Y177 HydrophobicContact CD-CE1 3.87Å; K85-Y177 HydrophobicContact CG-CD1 4.02Å; K85-Y177 HydrophobicContact CG-CE1 3.73Å; K85-Y177 HydrophobicContact CG-CE2 4.44Å; Y177-M234 WeakPolarHBondContact O-CA 3.41Å; Y177-I235 PolarHBondContact N-O 2.82Å; Y177-I235 VanDerWaalsContact N-O 3.08Å; Y177-I235 PolarHBondContact O-N 2.78Å; Y177-V239 HydrophobicContact CD1-CB 3.69Å; Y177-V239 HydrophobicContact CD1-CG2 3.78Å; Y177-V239 HydrophobicContact CD2-CG2 4.45Å; Y177-V239 HydrophobicContact CE1-CB 3.73Å; Y177-V239 HydrophobicContact CE1-CG2 4.23Å; Y177-V239 WeakPolarHBondContact CE1-O 3.4Å; Y177-V239 HydrophobicContact CG-CB 4.28Å; Y177-V239 HydrophobicContact CG-CG2 3.87Å; Y177-V239 PolarHBondContact OH-N 2.97Å; Y177-V239 PolarHBondContact OH-O 2.9Å
178Y97.4Very high90.9Very high3 Ų328.3 Ų28.31%0.01215%0.147CC..EExtended strand (participates in β ladder)trans-149.7160.8177.369.6-77.8000111.1I68 K71 C84 V86 L180 L184 I232 P233 M234I68-Y178 HydrophobicContact CD1-CD1 4.43Å; I68-Y178 HydrophobicContact CD1-CE1 3.76Å; I68-Y178 HydrophobicContact CD1-CE2 4.43Å; K71-Y178 WeakPolarHBondContact CD-OH 3.38Å; C84-Y178 HydrophobicContact CB-CD1 3.98Å; C84-Y178 HydrophobicContact CB-CD2 4.48Å; C84-Y178 HydrophobicContact CB-CE1 3.57Å; C84-Y178 HydrophobicContact CB-CE2 4.14Å; C84-Y178 HydrophobicContact CB-CG 4.43Å; C84-Y178 PolarHBondContact N-O 3.27Å; C84-Y178 PolarHBondContact O-N 3.46Å; V86-Y178 HydrophobicContact CG2-CD1 4.13Å; V86-Y178 HydrophobicContact CG2-CE1 3.84Å; Y178-L180 HydrophobicContact CD2-CD2 4.13Å; Y178-L180 HydrophobicContact CD2-CG 4.5Å; Y178-L180 HydrophobicContact CE2-CD2 4.08Å; Y178-L180 HydrophobicContact CE2-CG 4.32Å; Y178-L184 VanDerWaalsContact C-CD1 3.47Å; Y178-I232 HydrophobicContact CD2-CG2 3.38Å; Y178-I232 HydrophobicContact CE2-CD1 4.47Å; Y178-I232 HydrophobicContact CE2-CG2 4.07Å; Y178-I232 HydrophobicContact CG-CG2 3.71Å; Y178-P233 WeakPolarHBondContact CB-O 3.28Å; Y178-M234 HydrophobicContact CD1-CE 4.35Å
179S96Very high91.2Very high3 Ų328.1 Ų28.12%0.02115%0.147CC..  trans-132.1153.3161.4-178.50000108E82 T181 Y182E82-S179 VanDerWaalsContact O-CB 3.23Å; E82-S179 WeakPolarHBondContact O-CB 3.37Å; E82-S179 PolarHBondContact O-OG 3.45Å; S179-T181 PolarHBondContact OG-N 3.33Å; S179-Y182 WeakPolarHBondContact CB-O 3.46Å; S179-Y182 PolarHBondContact OG-N 3.46Å
180L92.7Very high91.5Very high117 Ų11730.2 Ų30.261%0.61315%0.154SC*.SBendtrans-91.1-13.8175.3-60.6179.1000112.3Y178 I232Y178-L180 HydrophobicContact CD2-CD2 4.13Å; Y178-L180 HydrophobicContact CD2-CG 4.5Å; Y178-L180 HydrophobicContact CE2-CD2 4.08Å; Y178-L180 HydrophobicContact CE2-CG 4.32Å; L180-I232 HydrophobicContact CD2-CD1 4.28Å; L180-I232 HydrophobicContact CD2-CG1 4.1Å; L180-I232 HydrophobicContact CD2-CG2 4.43Å
181T92.3Very high91.7Very high87 Ų8733.2 Ų33.253%0.53417%0.168SC..SBendtrans-125.8-13.4-173.8560000114.2H81 S179H81-T181 PolarHBondContact CE1-O 3.03Å; H81-T181 WeakPolarHBondContact ND1-CB 3.39Å; H81-T181 PolarHBondContact ND1-O 3.33Å; H81-T181 PolarHBondContact ND1-OG1 3.28Å; S179-T181 PolarHBondContact OG-N 3.33Å
182Y93.4Very high91.9Very high22 Ų2232.4 Ų32.49%0.08617%0.169CC..SBendtrans-124.1142.9178.2-176.1-90.9000112.1L77 H81 S179 L184 V188 Q191L77-Y182 HydrophobicContact CD1-CD1 3.59Å; L77-Y182 HydrophobicContact CD1-CE1 3.6Å; L77-Y182 HydrophobicContact CD1-CG 4.09Å; H81-Y182 HydrophobicContact CB-CD2 4.46Å; H81-Y182 HydrophobicContact CB-CG 4.38Å; H81-Y182 AromaticContact CD2-CD2 3.54Å; S179-Y182 WeakPolarHBondContact CB-O 3.46Å; S179-Y182 PolarHBondContact OG-N 3.46Å; Y182-L184 HydrophobicContact CD1-CD2 3.87Å; Y182-L184 HydrophobicContact CD1-CG 4.26Å; Y182-L184 HydrophobicContact CE1-CD2 4.14Å; Y182-L184 PolarHBondContact O-N 2.99Å; Y182-V188 WeakPolarHBondContact OH-CG2 3.45Å; Y182-Q191 PolarHBondContact OH-NE2 2.84Å
183D94.7Very high92Very high7 Ų730.9 Ų30.94%0.03716%0.164CC..  trans-83.999.9176-178.38.5000110.9T185 N186 Q191 L201D183-T185 VanDerWaalsContact CG-OG1 3.27Å; D183-T185 PolarHBondContact O-N 3.23Å; D183-T185 WeakPolarHBondContact OD1-CA 3.17Å; D183-T185 VanDerWaalsContact OD1-CB 3.26Å; D183-T185 WeakPolarHBondContact OD1-CB 3.5Å; D183-T185 PolarHBondContact OD1-N 2.97Å; D183-T185 PolarHBondContact OD1-OG1 2.84Å; D183-T185 PolarHBondContact OD2-OG1 3.42Å; D183-N186 WeakPolarHBondContact OD2-CB 3.44Å; D183-N186 PolarHBondContact OD2-ND2 3.49Å; D183-Q191 PolarHBondContact O-NE2 2.91Å; D183-L201 HydrophobicContact CB-CD1 3.93Å
184L97Very high91.8Very high5 Ų532.9 Ų32.93%0.02619%0.185CC..SBendtrans-72-12.3175.3-70.3175.8000114L77 V83 Y178 Y182 I235 I281 R283L77-L184 HydrophobicContact CD1-CD2 3.89Å; V83-L184 HydrophobicContact CG1-CD1 3.94Å; V83-L184 HydrophobicContact CG2-CD1 4.5Å; V83-L184 HydrophobicContact CG2-CD2 4.01Å; Y178-L184 VanDerWaalsContact C-CD1 3.47Å; Y182-L184 HydrophobicContact CD1-CD2 3.87Å; Y182-L184 HydrophobicContact CD1-CG 4.26Å; Y182-L184 HydrophobicContact CE1-CD2 4.14Å; Y182-L184 PolarHBondContact O-N 2.99Å; L184-I235 HydrophobicContact CB-CD1 4.14Å; L184-I235 HydrophobicContact CB-CG1 4.32Å; L184-I235 HydrophobicContact CB-CG2 4.18Å; L184-I281 HydrophobicContact CD2-CD1 4.28Å; L184-R283 VanDerWaalsContact O-CD 3.23Å; L184-R283 WeakPolarHBondContact O-CD 3.46Å; L184-R283 PolarHBondContact O-NH1 2.99Å; L184-R283 VanDerWaalsContact O-NH1 3.07Å
185T97.3Very high90.8Very high1 Ų137.8 Ų37.81%0.00621%0.208CC..SBendtrans-83-33.4-176.674.30000112.8D183 R190 V205 D206 F209 I235 R283D183-T185 VanDerWaalsContact CG-OG1 3.27Å; D183-T185 PolarHBondContact O-N 3.23Å; D183-T185 WeakPolarHBondContact OD1-CA 3.17Å; D183-T185 VanDerWaalsContact OD1-CB 3.26Å; D183-T185 WeakPolarHBondContact OD1-CB 3.5Å; D183-T185 PolarHBondContact OD1-N 2.97Å; D183-T185 PolarHBondContact OD1-OG1 2.84Å; D183-T185 PolarHBondContact OD2-OG1 3.42Å; T185-R190 PolarHBondContact O-NH2 3.45Å; T185-V205 HydrophobicContact CG2-CB 3.99Å; T185-V205 HydrophobicContact CG2-CG1 4.08Å; T185-V205 VanDerWaalsContact OG1-CA 3.25Å; T185-V205 WeakPolarHBondContact OG1-CA 3.39Å; T185-V205 WeakPolarHBondContact OG1-CB 3.41Å; T185-D206 WeakPolarHBondContact O-CB 3.38Å; T185-D206 PolarHBondContact OG1-N 2.91Å; T185-F209 HydrophobicContact CG2-CB 4.41Å; T185-F209 VanDerWaalsContact O-CD2 3.29Å; T185-F209 WeakPolarHBondContact O-CD2 3.32Å; T185-I235 HydrophobicContact CG2-CG2 3.84Å; T185-R283 WeakPolarHBondContact O-CD 3.43Å; T185-R283 PolarHBondContact O-NE 2.68Å
186N96.2Very high89.7Confident18 Ų1849.9 Ų49.910%0.09625%0.253CS..SBendtrans-94.6148.6176-83.4-64.8000111.9D183 R190 Q191 K204 D206 R283D183-N186 WeakPolarHBondContact OD2-CB 3.44Å; D183-N186 PolarHBondContact OD2-ND2 3.49Å; N186-R190 HydrophobicContact CB-CB 4.06Å; N186-R190 WeakPolarHBondContact OD1-CB 3.32Å; N186-R190 WeakPolarHBondContact OD1-CD 3.36Å; N186-R190 PolarHBondContact OD1-NE 3.26Å; N186-Q191 HydrophobicContact CB-CG 3.63Å; N186-Q191 PolarHBondContact O-NE2 3Å; N186-K204 PolarHBondContact ND2-O 3.14Å; N186-D206 PolarHBondContact ND2-N 2.94Å; N186-R283 PolarHBondContact O-NH1 3.17Å
187S96.3Very high88.3Confident4 Ų452.3 Ų52.33%0.02827%0.267CS..  trans-69.7158.5165.462.60000111.5Q189 R190 Q191 E311S187-Q189 PolarHBondContact O-N 3.33Å; S187-R190 PolarHBondContact O-N 3.16Å; S187-R190 PolarHBondContact OG-N 3.41Å; S187-R190 PolarHBondContact OG-NH1 3.23Å; S187-Q191 WeakPolarHBondContact O-CG 3.2Å; S187-Q191 PolarHBondContact O-N 3.48Å; S187-E311 WeakPolarHBondContact CA-OE1 3.45Å; S187-E311 WeakPolarHBondContact CB-OE1 3.3Å
188V95.4Very high87.2Confident12 Ų1255.9 Ų55.97%0.07331%0.306CS..Hα-helixtrans-52.4-41.6173.9169.40000110.4Y182 R190 Q191 S192 E311 L313 T320 V441Y182-V188 WeakPolarHBondContact OH-CG2 3.45Å; V188-R190 PolarHBondContact O-N 3.44Å; V188-Q191 PolarHBondContact O-N 3.45Å; V188-S192 WeakPolarHBondContact O-CB 3.45Å; V188-S192 PolarHBondContact O-N 3.45Å; V188-S192 PolarHBondContact O-OG 2.86Å; V188-E311 PolarHBondContact N-OE1 2.95Å; V188-L313 HydrophobicContact CB-CD2 4.38Å; V188-L313 HydrophobicContact CG2-CD1 4.21Å; V188-L313 HydrophobicContact CG2-CD2 3.57Å; V188-T320 HydrophobicContact CG1-CG2 4.4Å; V188-T320 HydrophobicContact CG2-CG2 4.34Å; V188-V441 HydrophobicContact CG1-CB 4.5Å; V188-V441 HydrophobicContact CG1-CG2 3.79Å
189Q94.8Very high86.6Confident41 Ų4161.5 Ų61.519%0.19233%0.327CS..Hα-helixtrans-56.9-49.2175.4-176.8153.9-64.300112.5S187 Q191 S192 T193 C439 K449 Q450S187-Q189 PolarHBondContact O-N 3.33Å; Q189-Q191 VanDerWaalsContact C-N 3.35Å; Q189-Q191 PolarHBondContact O-N 2.66Å; Q189-S192 PolarHBondContact O-N 3Å; Q189-T193 HydrophobicContact CG-CG2 4.35Å; Q189-T193 WeakPolarHBondContact O-CB 3.33Å; Q189-T193 WeakPolarHBondContact O-CG2 3.49Å; Q189-T193 PolarHBondContact O-N 3.19Å; Q189-T193 PolarHBondContact O-OG1 3.38Å; Q189-C439 HydrophobicContact CB-CB 3.89Å; Q189-C439 HydrophobicContact CG-CB 4.44Å; Q189-K449 VanDerWaalsContact OE1-CA 3.3Å; Q189-Q450 PolarHBondContact NE2-O 2.99Å
190R93Very high86.1Confident47 Ų4762.9 Ų62.918%0.17734%0.336CS..Hα-helixtrans-63.4-42.8-179-70.6-165.1-64.3-84.58111.1T185 N186 S187 V188 T193 G194 D206 E309T185-R190 PolarHBondContact O-NH2 3.45Å; N186-R190 HydrophobicContact CB-CB 4.06Å; N186-R190 WeakPolarHBondContact OD1-CB 3.32Å; N186-R190 WeakPolarHBondContact OD1-CD 3.36Å; N186-R190 PolarHBondContact OD1-NE 3.26Å; S187-R190 PolarHBondContact O-N 3.16Å; S187-R190 PolarHBondContact OG-N 3.41Å; S187-R190 PolarHBondContact OG-NH1 3.23Å; V188-R190 PolarHBondContact O-N 3.44Å; R190-T193 PolarHBondContact O-N 2.95Å; R190-T193 PolarHBondContact O-OG1 2.92Å; R190-G194 PolarHBondContact O-N 2.87Å; R190-D206 IonicContact CZ-OD2 3.79Å; R190-D206 VanDerWaalsContact CZ-OD2 3.27Å; R190-D206 IonicContact NE-OD2 3.56Å; R190-D206 PolarHBondContact NE-OD2 3.07Å; R190-D206 IonicContact NH2-OD2 3.32Å; R190-D206 PolarHBondContact NH2-OD2 2.85Å; R190-E309 IonicContact CZ-OE1 2.73Å; R190-E309 IonicContact CZ-OE2 3.1Å; R190-E309 IonicContact NH1-OE1 3.53Å; R190-E309 PolarHBondContact NH1-OE1 2.89Å; R190-E309 IonicContact NH1-OE2 3.35Å; R190-E309 PolarHBondContact NH1-OE2 2.81Å; R190-E309 IonicContact NH2-OE1 3.63Å; R190-E309 PolarHBondContact NH2-OE1 2.89Å; R190-E309 IonicContact NH2-OE2 3.22Å; R190-E309 PolarHBondContact NH2-OE2 2.91Å
191Q91.6Very high85.9Confident64 Ų6459.7 Ų59.730%0.29932%0.319SS..Hα-helixtrans-62.5-46.2177.2-64-177.461.600112.3Y182 D183 N186 S187 V188 Q189 T193 G194Y182-Q191 PolarHBondContact OH-NE2 2.84Å; D183-Q191 PolarHBondContact O-NE2 2.91Å; N186-Q191 HydrophobicContact CB-CG 3.63Å; N186-Q191 PolarHBondContact O-NE2 3Å; S187-Q191 WeakPolarHBondContact O-CG 3.2Å; S187-Q191 PolarHBondContact O-N 3.48Å; V188-Q191 PolarHBondContact O-N 3.45Å; Q189-Q191 VanDerWaalsContact C-N 3.35Å; Q189-Q191 PolarHBondContact O-N 2.66Å; Q191-T193 VanDerWaalsContact C-N 3.34Å; Q191-T193 PolarHBondContact O-N 2.92Å; Q191-G194 PolarHBondContact O-N 3.32Å
192S88.2Confident85.7Confident48 Ų4857.2 Ų57.234%0.33630%0.3SS..Hα-helixtrans-79.4-9.7-178.7-55.30000114.7V188 Q189 V446V188-S192 WeakPolarHBondContact O-CB 3.45Å; V188-S192 PolarHBondContact O-N 3.45Å; V188-S192 PolarHBondContact O-OG 2.86Å; Q189-S192 PolarHBondContact O-N 3Å; S192-V446 WeakPolarHBondContact O-CG2 3.32Å
193T78.3Confident85.6Confident72 Ų7259.7 Ų59.744%0.44231%0.312SS..Hα-helixtrans-94.7-9.3170.154.60000114.6Q189 R190 Q191 K449Q189-T193 HydrophobicContact CG-CG2 4.35Å; Q189-T193 WeakPolarHBondContact O-CB 3.33Å; Q189-T193 WeakPolarHBondContact O-CG2 3.49Å; Q189-T193 PolarHBondContact O-N 3.19Å; Q189-T193 PolarHBondContact O-OG1 3.38Å; R190-T193 PolarHBondContact O-N 2.95Å; R190-T193 PolarHBondContact O-OG1 2.92Å; Q191-T193 VanDerWaalsContact C-N 3.34Å; Q191-T193 PolarHBondContact O-N 2.92Å; T193-K449 HydrophobicContact CG2-CD 4.36Å
194G67.1Low85.3Confident47 Ų4763.5 Ų63.549%0.48533%0.329SS..SBendtrans-75155.3173.300000112.2R190 Q191R190-G194 PolarHBondContact O-N 2.87Å; Q191-G194 PolarHBondContact O-N 3.32Å
195E61.9Low85.1Confident183 Ų18364.3 Ų64.386%0.85533%0.334SS*.  trans-63.3156.3166.3-62.7-174.3155.400110.5D197E195-D197 PolarHBondContact O-N 3.15Å
196R66.2Low85.1Confident255 Ų25565.1 Ų65.196%0.96234%0.338SS*.  trans-73.966.8173.3-73.9-166.1179.9-1633.1111.2
197D65.7Low85Confident54 Ų5467 Ų6729%0.28935%0.348SS..  trans-69.5138.1-178-173.8-28.6000111.3E195 R199 K204E195-D197 PolarHBondContact O-N 3.15Å; D197-R199 VanDerWaalsContact C-N 3.31Å; D197-R199 PolarHBondContact O-N 3.14Å; D197-R199 VanDerWaalsContact OD1-CB 3.25Å; D197-R199 WeakPolarHBondContact OD1-CB 3.46Å; D197-R199 VanDerWaalsContact OD1-CG 3.27Å; D197-R199 WeakPolarHBondContact OD1-CG 3.28Å; D197-R199 PolarHBondContact OD1-N 3.5Å; D197-R199 IonicContact OD1-NE 3.51Å; D197-R199 PolarHBondContact OD1-NE 2.75Å; D197-R199 IonicContact OD2-CZ 2.73Å; D197-R199 IonicContact OD2-NE 3.78Å; D197-R199 PolarHBondContact OD2-NE 2.99Å; D197-R199 IonicContact OD2-NH2 3.09Å; D197-R199 PolarHBondContact OD2-NH2 3.23Å; D197-K204 VanDerWaalsContact O-CE 3.29Å; D197-K204 WeakPolarHBondContact O-CE 3.26Å; D197-K204 PolarHBondContact O-NZ 3.29Å
198G75.1Confident85Confident83 Ų8367.7 Ų67.786%0.85635%0.35SS*.  trans-76.4-9.4177.700000115.3
199R85.4Confident85.1Confident122 Ų12267.1 Ų67.146%0.4635%0.347SS..SBendtrans-58.9149.8-176-80-174.8-67.6158.5-1.1113.8D197 Q203 K204D197-R199 VanDerWaalsContact C-N 3.31Å; D197-R199 PolarHBondContact O-N 3.14Å; D197-R199 VanDerWaalsContact OD1-CB 3.25Å; D197-R199 WeakPolarHBondContact OD1-CB 3.46Å; D197-R199 VanDerWaalsContact OD1-CG 3.27Å; D197-R199 WeakPolarHBondContact OD1-CG 3.28Å; D197-R199 PolarHBondContact OD1-N 3.5Å; D197-R199 IonicContact OD1-NE 3.51Å; D197-R199 PolarHBondContact OD1-NE 2.75Å; D197-R199 IonicContact OD2-CZ 2.73Å; D197-R199 IonicContact OD2-NE 3.78Å; D197-R199 PolarHBondContact OD2-NE 2.99Å; D197-R199 IonicContact OD2-NH2 3.09Å; D197-R199 PolarHBondContact OD2-NH2 3.23Å; R199-Q203 HydrophobicContact CB-CB 4.22Å; R199-Q203 VanDerWaalsContact CD-OE1 3.28Å; R199-Q203 PolarHBondContact NH1-O 3.17Å; R199-K204 WeakPolarHBondContact O-CE 3.39Å; R199-K204 PolarHBondContact O-NZ 3.3Å
200P86.4Confident85.2Confident32 Ų3265.3 Ų65.321%0.20834%0.338CS..  trans-61.4154.9174.729.9-39000111.8W202 Q203 N228P200-W202 VanDerWaalsContact C-N 3.28Å; P200-W202 PolarHBondContact O-N 2.91Å; P200-W202 VanDerWaalsContact O-N 3.14Å; P200-Q203 HydrophobicContact CG-CB 4.32Å; P200-Q203 HydrophobicContact CG-CG 3.87Å; P200-Q203 PolarHBondContact O-N 2.92Å; P200-N228 HydrophobicContact CB-CB 3.98Å; P200-N228 WeakPolarHBondContact CG-OD1 3.47Å
201L87.3Confident85.3Confident49 Ų4963.1 Ų63.126%0.25733%0.33SS..G310 helixtrans-45.8-50.2-174.9-170.372.1000112.7D183 Q203 K204 V205 P233D183-L201 HydrophobicContact CB-CD1 3.93Å; L201-Q203 PolarHBondContact O-N 3.08Å; L201-Q203 VanDerWaalsContact O-N 3.1Å; L201-K204 PolarHBondContact O-N 2.97Å; L201-V205 WeakPolarHBondContact O-CG1 3.14Å; L201-P233 HydrophobicContact CD2-CG 4.42Å
202W89.1Confident85.5Confident35 Ų3560.1 Ų60.113%0.13332%0.316CS..G310 helixtrans-65.9-11.8-175.274-95.4000115.8P200 V205 F210 T220 N228 I231 P233P200-W202 VanDerWaalsContact C-N 3.28Å; P200-W202 PolarHBondContact O-N 2.91Å; P200-W202 VanDerWaalsContact O-N 3.14Å; W202-V205 VanDerWaalsContact O-CG2 3.23Å; W202-V205 WeakPolarHBondContact O-CG2 3.23Å; W202-F210 HydrophobicContact CB-CE1 4.33Å; W202-F210 HydrophobicContact CB-CZ 4.32Å; W202-T220 HydrophobicContact CE3-CG2 3.97Å; W202-T220 HydrophobicContact CH2-CG2 4.15Å; W202-T220 HydrophobicContact CZ3-CG2 3.63Å; W202-N228 PolarHBondContact NE1-OD1 3.04Å; W202-I231 HydrophobicContact CB-CB 4.38Å; W202-I231 HydrophobicContact CB-CG2 3.39Å; W202-I231 HydrophobicContact CD2-CD1 3.81Å; W202-I231 HydrophobicContact CD2-CG2 3.96Å; W202-I231 VanDerWaalsContact CE2-CD1 3.43Å; W202-I231 HydrophobicContact CE3-CD1 4.37Å; W202-I231 HydrophobicContact CG-CB 4.04Å; W202-I231 HydrophobicContact CG-CD1 4.18Å; W202-I231 HydrophobicContact CG-CG2 3.43Å; W202-I231 VanDerWaalsContact CG-CG2 3.43Å; W202-I231 HydrophobicContact CH2-CD1 4.28Å; W202-I231 HydrophobicContact CZ2-CD1 3.7Å; W202-P233 HydrophobicContact CB-CG 3.75Å
203Q89.8Confident85.8Confident74 Ų7461.7 Ų61.735%0.34632%0.317SS..G310 helixtrans-95.4-6.2175.5-67.6-179.50.200113.3R199 P200 L201R199-Q203 HydrophobicContact CB-CB 4.22Å; R199-Q203 VanDerWaalsContact CD-OE1 3.28Å; R199-Q203 PolarHBondContact NH1-O 3.17Å; P200-Q203 HydrophobicContact CG-CB 4.32Å; P200-Q203 HydrophobicContact CG-CG 3.87Å; P200-Q203 PolarHBondContact O-N 2.92Å; L201-Q203 PolarHBondContact O-N 3.08Å; L201-Q203 VanDerWaalsContact O-N 3.1Å
204K89.6Confident86.6Confident87 Ų8762.1 Ų62.138%0.37831%0.311SS..THydrogen-bonded Turntrans-102.3-15.6178.6-68.8162.3166.4164.20113.3N186 D197 R199 L201N186-K204 PolarHBondContact ND2-O 3.14Å; D197-K204 VanDerWaalsContact O-CE 3.29Å; D197-K204 WeakPolarHBondContact O-CE 3.26Å; D197-K204 PolarHBondContact O-NZ 3.29Å; R199-K204 WeakPolarHBondContact O-CE 3.39Å; R199-K204 PolarHBondContact O-NZ 3.3Å; L201-K204 PolarHBondContact O-N 2.97Å
205V93.6Very high87.8Confident22 Ų2260 Ų6013%0.13329%0.288CS..SBendtrans-61.6148.9-174.3-61.70000114.1T185 L201 W202 D207 F210 P233T185-V205 HydrophobicContact CG2-CB 3.99Å; T185-V205 HydrophobicContact CG2-CG1 4.08Å; T185-V205 VanDerWaalsContact OG1-CA 3.25Å; T185-V205 WeakPolarHBondContact OG1-CA 3.39Å; T185-V205 WeakPolarHBondContact OG1-CB 3.41Å; L201-V205 WeakPolarHBondContact O-CG1 3.14Å; W202-V205 VanDerWaalsContact O-CG2 3.23Å; W202-V205 WeakPolarHBondContact O-CG2 3.23Å; V205-D207 PolarHBondContact O-N 2.96Å; V205-F210 HydrophobicContact CB-CD1 4.5Å; V205-F210 HydrophobicContact CG2-CB 4.17Å; V205-F210 HydrophobicContact CG2-CD1 3.33Å; V205-F210 HydrophobicContact CG2-CE1 3.86Å; V205-F210 HydrophobicContact CG2-CG 4.01Å; V205-P233 HydrophobicContact CG1-CB 3.92Å; V205-P233 HydrophobicContact CG1-CG 3.97Å
206D95.5Very high89.3Confident19 Ų1951.2 Ų51.210%0.10225%0.248CC..  trans-68.8106.9167.4-167.3-29.4000109.1T185 N186 R190 R208 F209 F210T185-D206 WeakPolarHBondContact O-CB 3.38Å; T185-D206 PolarHBondContact OG1-N 2.91Å; N186-D206 PolarHBondContact ND2-N 2.94Å; R190-D206 IonicContact CZ-OD2 3.79Å; R190-D206 VanDerWaalsContact CZ-OD2 3.27Å; R190-D206 IonicContact NE-OD2 3.56Å; R190-D206 PolarHBondContact NE-OD2 3.07Å; R190-D206 IonicContact NH2-OD2 3.32Å; R190-D206 PolarHBondContact NH2-OD2 2.85Å; D206-R208 PolarHBondContact O-N 3.34Å; D206-R208 VanDerWaalsContact O-N 3.09Å; D206-R208 VanDerWaalsContact OD1-CB 3.27Å; D206-R208 WeakPolarHBondContact OD1-CB 3.48Å; D206-R208 VanDerWaalsContact OD1-CG 3.31Å; D206-R208 WeakPolarHBondContact OD1-CG 3.44Å; D206-R208 IonicContact OD1-CZ 3.01Å; D206-R208 PolarHBondContact OD1-N 3.11Å; D206-R208 IonicContact OD1-NE 2.71Å; D206-R208 PolarHBondContact OD1-NE 2.79Å; D206-R208 IonicContact OD1-NH2 3.19Å; D206-R208 IonicContact OD2-CZ 3.83Å; D206-R208 IonicContact OD2-NE 3.78Å; D206-R208 PolarHBondContact OD2-NE 3.47Å; D206-R208 IonicContact OD2-NH2 2.71Å; D206-R208 PolarHBondContact OD2-NH2 3.35Å; D206-F209 HydrophobicContact CB-CD2 3.95Å; D206-F209 PolarHBondContact O-N 2.98Å; D206-F209 WeakPolarHBondContact OD2-CD2 3.41Å; D206-F209 WeakPolarHBondContact OD2-CE2 3.22Å; D206-F210 PolarHBondContact O-N 2.94Å
207D95.1Very high90.5Very high56 Ų5642.7 Ų42.730%0.29922%0.218SC..G310 helixtrans-48.7-40.5-179.3175.986.1000111.8V205 F209 F210 K213 R286 H287V205-D207 PolarHBondContact O-N 2.96Å; D207-F209 PolarHBondContact O-N 3.31Å; D207-F210 PolarHBondContact O-N 2.71Å; D207-F210 VanDerWaalsContact O-N 3.12Å; D207-K213 WeakPolarHBondContact OD1-CD 3.03Å; D207-K213 IonicContact OD1-NZ 2.7Å; D207-K213 PolarHBondContact OD1-NZ 2.83Å; D207-R286 WeakPolarHBondContact O-CD 3.47Å; D207-H287 IonicContact OD2-CE1 2.86Å; D207-H287 PolarHBondContact OD2-CE1 3.42Å; D207-H287 VanDerWaalsContact OD2-CE1 3.32Å; D207-H287 IonicContact OD2-NE2 2.66Å; D207-H287 PolarHBondContact OD2-NE2 3.25Å
208R95.7Very high91.6Very high20 Ų2042 Ų428%0.07522%0.215CC..G310 helixtrans-55-29.4-178.3-53.3176-60.21585111.4D206 S285 R286 E309 E364 Y369D206-R208 PolarHBondContact O-N 3.34Å; D206-R208 VanDerWaalsContact O-N 3.09Å; D206-R208 VanDerWaalsContact OD1-CB 3.27Å; D206-R208 WeakPolarHBondContact OD1-CB 3.48Å; D206-R208 VanDerWaalsContact OD1-CG 3.31Å; D206-R208 WeakPolarHBondContact OD1-CG 3.44Å; D206-R208 IonicContact OD1-CZ 3.01Å; D206-R208 PolarHBondContact OD1-N 3.11Å; D206-R208 IonicContact OD1-NE 2.71Å; D206-R208 PolarHBondContact OD1-NE 2.79Å; D206-R208 IonicContact OD1-NH2 3.19Å; D206-R208 IonicContact OD2-CZ 3.83Å; D206-R208 IonicContact OD2-NE 3.78Å; D206-R208 PolarHBondContact OD2-NE 3.47Å; D206-R208 IonicContact OD2-NH2 2.71Å; D206-R208 PolarHBondContact OD2-NH2 3.35Å; R208-S285 CarbonylContact O-C 3.56Å; R208-S285 WeakPolarHBondContact O-CA 3.47Å; R208-S285 PolarHBondContact O-OG 2.96Å; R208-R286 WeakPolarHBondContact O-CG 3.42Å; R208-R286 PolarHBondContact O-N 2.98Å; R208-E309 IonicContact NH2-OE2 2.65Å; R208-E364 WeakPolarHBondContact CD-OE1 3.42Å; R208-E364 IonicContact NH1-OE1 3.79Å; R208-Y369 PolarHBondContact NH1-OH 2.91Å; R208-Y369 PolarHBondContact NH2-OH 3.02Å
209F97.7Very high92.4Very high0 Ų038 Ų380%017%0.174CC..G310 helixtrans-112-2.7-177.1-53.4-60.9000114.6T185 D206 D207 W211 I235 R283 Y307 E309T185-F209 HydrophobicContact CG2-CB 4.41Å; T185-F209 VanDerWaalsContact O-CD2 3.29Å; T185-F209 WeakPolarHBondContact O-CD2 3.32Å; D206-F209 HydrophobicContact CB-CD2 3.95Å; D206-F209 PolarHBondContact O-N 2.98Å; D206-F209 WeakPolarHBondContact OD2-CD2 3.41Å; D206-F209 WeakPolarHBondContact OD2-CE2 3.22Å; D207-F209 PolarHBondContact O-N 3.31Å; F209-W211 VanDerWaalsContact C-N 3.35Å; F209-W211 PolarHBondContact O-N 3.14Å; F209-I235 HydrophobicContact CB-CG2 4.28Å; F209-R283 HydrophobicContact CB-CB 4.11Å; F209-R283 HydrophobicContact CD1-CB 3.4Å; F209-R283 HydrophobicContact CD2-CB 4.15Å; F209-R283 HydrophobicContact CE1-CB 3.75Å; F209-R283 VanDerWaalsContact CE1-O 3.24Å; F209-R283 WeakPolarHBondContact CE1-O 3.48Å; F209-R283 HydrophobicContact CE2-CB 4.44Å; F209-R283 HydrophobicContact CG-CB 3.61Å; F209-R283 HydrophobicContact CG-CG 4.32Å; F209-R283 HydrophobicContact CZ-CB 4.26Å; F209-Y307 HydrophobicContact CE1-CD1 4.3Å; F209-Y307 HydrophobicContact CZ-CD1 4.21Å; F209-Y307 HydrophobicContact CZ-CE1 4.03Å; F209-E309 HydrophobicContact CE1-CB 4.26Å; F209-E309 HydrophobicContact CE2-CB 4.14Å; F209-E309 HydrophobicContact CZ-CB 3.56Å
210F96.8Very high92.5Very high3 Ų333.9 Ų33.91%0.01316%0.162CC..  trans-75.384.3173.3-167.1175.5000110.1W202 V205 D206 D207 N212 K213 I216 I231 P233 R286W202-F210 HydrophobicContact CB-CE1 4.33Å; W202-F210 HydrophobicContact CB-CZ 4.32Å; V205-F210 HydrophobicContact CB-CD1 4.5Å; V205-F210 HydrophobicContact CG2-CB 4.17Å; V205-F210 HydrophobicContact CG2-CD1 3.33Å; V205-F210 HydrophobicContact CG2-CE1 3.86Å; V205-F210 HydrophobicContact CG2-CG 4.01Å; D206-F210 PolarHBondContact O-N 2.94Å; D207-F210 PolarHBondContact O-N 2.71Å; D207-F210 VanDerWaalsContact O-N 3.12Å; F210-N212 WeakPolarHBondContact CD2-OD1 3.46Å; F210-N212 WeakPolarHBondContact CE2-OD1 3.29Å; F210-N212 PolarHBondContact O-N 2.75Å; F210-K213 HydrophobicContact CB-CB 4.27Å; F210-K213 HydrophobicContact CD1-CB 3.85Å; F210-K213 HydrophobicContact CD1-CD 3.88Å; F210-K213 HydrophobicContact CD1-CG 3.96Å; F210-K213 HydrophobicContact CD2-CB 3.93Å; F210-K213 HydrophobicContact CE1-CB 4.24Å; F210-K213 HydrophobicContact CE1-CD 4.42Å; F210-K213 HydrophobicContact CE1-CG 4.16Å; F210-K213 HydrophobicContact CE2-CB 4.25Å; F210-K213 HydrophobicContact CG-CB 3.74Å; F210-K213 HydrophobicContact CG-CD 4.41Å; F210-K213 HydrophobicContact CG-CG 4.36Å; F210-K213 HydrophobicContact CZ-CB 4.44Å; F210-K213 WeakPolarHBondContact O-CB 3.44Å; F210-K213 PolarHBondContact O-N 3.39Å; F210-I216 HydrophobicContact CE2-CD1 3.91Å; F210-I216 HydrophobicContact CZ-CD1 3.66Å; F210-I231 HydrophobicContact CZ-CG2 4.06Å; F210-P233 HydrophobicContact CD2-CB 4.24Å; F210-P233 HydrophobicContact CE2-CB 4.04Å; F210-P233 HydrophobicContact CE2-CG 4.46Å; F210-P233 HydrophobicContact CZ-CB 4.34Å; F210-P233 HydrophobicContact CZ-CG 4.32Å; F210-R286 PolarHBondContact O-NH1 3.33Å
211W95.5Very high92.6Very high0 Ų038.3 Ų38.30%018%0.18CC..THydrogen-bonded Turntrans-66.9-43.8-165.2-168-83.4000113.6F176 F209 K213 M234 Q236 R284 S285 R286 A289 I562 Q566F176-W211 AromaticContact CE1-CD1 3.58Å; F176-W211 HydrophobicContact CE1-CD2 4.5Å; F176-W211 HydrophobicContact CE1-CG 4.03Å; F176-W211 AromaticContact CE1-NE1 3.75Å; F209-W211 VanDerWaalsContact C-N 3.35Å; F209-W211 PolarHBondContact O-N 3.14Å; W211-K213 VanDerWaalsContact C-N 3.35Å; W211-M234 VanDerWaalsContact CB-O 3.29Å; W211-M234 WeakPolarHBondContact CB-O 3.38Å; W211-M234 PolarHBondContact N-O 3.11Å; W211-Q236 HydrophobicContact CB-CB 4.5Å; W211-Q236 HydrophobicContact CD2-CB 3.56Å; W211-Q236 HydrophobicContact CE3-CB 3.49Å; W211-Q236 VanDerWaalsContact CE3-CB 3.49Å; W211-Q236 HydrophobicContact CG-CB 4.02Å; W211-Q236 HydrophobicContact CH2-CB 4.34Å; W211-Q236 VanDerWaalsContact CH2-OE1 3.29Å; W211-Q236 HydrophobicContact CZ2-CB 4.45Å; W211-Q236 HydrophobicContact CZ3-CB 3.89Å; W211-R284 HydrophobicContact CZ3-CB 4.24Å; W211-R284 HydrophobicContact CZ3-CG 4.08Å; W211-S285 VanDerWaalsContact CZ3-O 3.31Å; W211-S285 WeakPolarHBondContact CZ3-O 3.37Å; W211-R286 HydrophobicContact CE3-CB 4.37Å; W211-R286 PolarHBondContact O-NH1 3.16Å; W211-R286 VanDerWaalsContact O-NH1 3.14Å; W211-A289 HydrophobicContact CH2-CB 3.5Å; W211-A289 VanDerWaalsContact CH2-CB 3.5Å; W211-A289 HydrophobicContact CZ2-CB 4.24Å; W211-A289 HydrophobicContact CZ3-CB 4.17Å; W211-I562 HydrophobicContact CZ2-CG2 4.39Å; W211-Q566 VanDerWaalsContact NE1-NE2 3.16Å; W211-Q566 PolarHBondContact O-NE2 3.14Å; W211-Q566 PolarHBondContact O-OE1 3.32Å
212N95.8Very high92.5Very high2 Ų238.5 Ų38.51%0.01118%0.181CC..THydrogen-bonded Turntrans-861.7-175.663.5-45.7000114.2I52 F210 Y214 M215 I216 I232 M234I52-N212 HydrophobicContact CG2-CB 4.44Å; I52-N212 PolarHBondContact O-ND2 2.81Å; I52-N212 VanDerWaalsContact O-ND2 3.17Å; F210-N212 WeakPolarHBondContact CD2-OD1 3.46Å; F210-N212 WeakPolarHBondContact CE2-OD1 3.29Å; F210-N212 PolarHBondContact O-N 2.75Å; N212-Y214 VanDerWaalsContact C-N 3.3Å; N212-Y214 PolarHBondContact O-N 3.34Å; N212-Y214 VanDerWaalsContact O-N 3.12Å; N212-M215 HydrophobicContact CB-SD 4.26Å; N212-M215 WeakPolarHBondContact O-CA 3.29Å; N212-M215 WeakPolarHBondContact O-CB 3.33Å; N212-M215 PolarHBondContact O-N 3.34Å; N212-I216 PolarHBondContact O-N 2.86Å; N212-I232 PolarHBondContact ND2-O 2.83Å; N212-I232 PolarHBondContact OD1-O 3.08Å; N212-M234 HydrophobicContact CB-SD 4.49Å; N212-M234 WeakPolarHBondContact OD1-CB 3.23Å; N212-M234 PolarHBondContact OD1-N 3.35Å
213K94.9Very high92Very high81 Ų8140.1 Ų40.135%0.35221%0.209SC..G310 helixtrans-46.3-46.7-174.3-176.5176171176.30114.3D207 F210 W211 I216 Q217D207-K213 WeakPolarHBondContact OD1-CD 3.03Å; D207-K213 IonicContact OD1-NZ 2.7Å; D207-K213 PolarHBondContact OD1-NZ 2.83Å; F210-K213 HydrophobicContact CB-CB 4.27Å; F210-K213 HydrophobicContact CD1-CB 3.85Å; F210-K213 HydrophobicContact CD1-CD 3.88Å; F210-K213 HydrophobicContact CD1-CG 3.96Å; F210-K213 HydrophobicContact CD2-CB 3.93Å; F210-K213 HydrophobicContact CE1-CB 4.24Å; F210-K213 HydrophobicContact CE1-CD 4.42Å; F210-K213 HydrophobicContact CE1-CG 4.16Å; F210-K213 HydrophobicContact CE2-CB 4.25Å; F210-K213 HydrophobicContact CG-CB 3.74Å; F210-K213 HydrophobicContact CG-CD 4.41Å; F210-K213 HydrophobicContact CG-CG 4.36Å; F210-K213 HydrophobicContact CZ-CB 4.44Å; F210-K213 WeakPolarHBondContact O-CB 3.44Å; F210-K213 PolarHBondContact O-N 3.39Å; W211-K213 VanDerWaalsContact C-N 3.35Å; K213-I216 VanDerWaalsContact O-CG1 3.24Å; K213-I216 WeakPolarHBondContact O-CG1 3.49Å; K213-I216 PolarHBondContact O-N 3.36Å; K213-Q217 PolarHBondContact O-N 2.92Å
214Y93.7Very high91.7Very high80 Ų8039.6 Ų39.631%0.31421%0.21SC..G310 helixtrans-64.6-39.6177.6176-98.6000112.9N212 I216 Q217N212-Y214 VanDerWaalsContact C-N 3.3Å; N212-Y214 PolarHBondContact O-N 3.34Å; N212-Y214 VanDerWaalsContact O-N 3.12Å; Y214-I216 PolarHBondContact O-N 3.24Å; Y214-I216 VanDerWaalsContact O-N 3.14Å; Y214-Q217 VanDerWaalsContact O-CB 3.31Å; Y214-Q217 WeakPolarHBondContact O-CB 3.24Å; Y214-Q217 PolarHBondContact O-N 3.18Å; Y214-Q217 VanDerWaalsContact O-N 3.12Å
215M93.6Very high91.4Very high2 Ų240.1 Ų40.11%0.0122%0.223CC..G310 helixtrans-65.3-19.6-178.6-51.5175.462.100112.4I52 G53 K54 I66 N212 M565I52-M215 HydrophobicContact CG2-CE 4.03Å; I52-M215 HydrophobicContact CG2-SD 4.41Å; G53-M215 CarbonylContact C-O 3.5Å; G53-M215 WeakPolarHBondContact CA-O 3.46Å; K54-M215 PolarHBondContact N-O 2.85Å; K54-M215 WeakPolarHBondContact O-CA 3.23Å; K54-M215 WeakPolarHBondContact O-CB 3.47Å; I66-M215 HydrophobicContact CD1-CE 3.59Å; N212-M215 HydrophobicContact CB-SD 4.26Å; N212-M215 WeakPolarHBondContact O-CA 3.29Å; N212-M215 WeakPolarHBondContact O-CB 3.33Å; N212-M215 PolarHBondContact O-N 3.34Å; M215-M565 HydrophobicContact CE-CE 4.27Å; M215-M565 HydrophobicContact CE-CG 4.37Å; M215-M565 WeakPolarHBondContact CG-O 3.31Å; M215-M565 HydrophobicContact SD-CB 4Å; M215-M565 HydrophobicContact SD-CE 3.57Å; M215-M565 VanDerWaalsContact SD-CE 3.57Å; M215-M565 HydrophobicContact SD-CG 3.92Å
216I93.4Very high91Very high0 Ų042.6 Ų42.60%024%0.235CC..G310 helixtrans-112.918.7178.160.3165000112.7I52 F210 N212 K213 Y214 D218 L219 T220 I231I52-I216 VanDerWaalsContact O-CG2 3.27Å; I52-I216 WeakPolarHBondContact O-CG2 3.17Å; F210-I216 HydrophobicContact CE2-CD1 3.91Å; F210-I216 HydrophobicContact CZ-CD1 3.66Å; N212-I216 PolarHBondContact O-N 2.86Å; K213-I216 VanDerWaalsContact O-CG1 3.24Å; K213-I216 WeakPolarHBondContact O-CG1 3.49Å; K213-I216 PolarHBondContact O-N 3.36Å; Y214-I216 PolarHBondContact O-N 3.24Å; Y214-I216 VanDerWaalsContact O-N 3.14Å; I216-D218 VanDerWaalsContact C-N 3.32Å; I216-D218 PolarHBondContact O-N 3.3Å; I216-L219 HydrophobicContact CB-CB 4.42Å; I216-L219 HydrophobicContact CB-CD1 4.25Å; I216-L219 HydrophobicContact CG2-CD1 4.27Å; I216-L219 WeakPolarHBondContact O-CA 3.1Å; I216-L219 WeakPolarHBondContact O-CB 3.48Å; I216-L219 PolarHBondContact O-N 3.36Å; I216-T220 HydrophobicContact CD1-CG2 4.23Å; I216-T220 HydrophobicContact CG1-CG2 4.39Å; I216-T220 PolarHBondContact O-N 3.44Å; I216-I231 HydrophobicContact CD1-CB 4.42Å; I216-I231 HydrophobicContact CD1-CG1 4.35Å; I216-I231 HydrophobicContact CD1-CG2 3.6Å
217Q91.7Very high90.7Very high75 Ų7541.8 Ų41.835%0.3523%0.231SC..Hα-helixtrans-52.4-47.4-172.6180167.4-13.200112.4K213 Y214 L219 T220 E221K213-Q217 PolarHBondContact O-N 2.92Å; Y214-Q217 VanDerWaalsContact O-CB 3.31Å; Y214-Q217 WeakPolarHBondContact O-CB 3.24Å; Y214-Q217 PolarHBondContact O-N 3.18Å; Y214-Q217 VanDerWaalsContact O-N 3.12Å; Q217-L219 VanDerWaalsContact C-N 3.27Å; Q217-L219 PolarHBondContact O-N 2.85Å; Q217-T220 PolarHBondContact O-N 2.81Å; Q217-T220 PolarHBondContact O-OG1 3.05Å; Q217-E221 HydrophobicContact CG-CG 4.33Å; Q217-E221 WeakPolarHBondContact CG-OE1 3.24Å; Q217-E221 PolarHBondContact NE2-OE1 2.56Å; Q217-E221 WeakPolarHBondContact O-CG 3.35Å; Q217-E221 PolarHBondContact O-N 3.2Å
218D88.9Confident90.4Very high39 Ų3941.6 Ų41.621%0.20923%0.23CC..Hα-helixtrans-46-47.4171.2-62.449.4000113.1L28 K54 I216 T220 E221 I222L28-D218 HydrophobicContact CB-CB 4.17Å; L28-D218 HydrophobicContact CD1-CB 4.03Å; K54-D218 WeakPolarHBondContact CE-OD1 3.14Å; K54-D218 IonicContact NZ-OD1 2.75Å; K54-D218 PolarHBondContact NZ-OD1 2.91Å; K54-D218 IonicContact NZ-OD2 2.79Å; K54-D218 PolarHBondContact NZ-OD2 3.08Å; I216-D218 VanDerWaalsContact C-N 3.32Å; I216-D218 PolarHBondContact O-N 3.3Å; D218-T220 VanDerWaalsContact C-N 3.31Å; D218-T220 PolarHBondContact O-N 2.77Å; D218-E221 PolarHBondContact O-N 2.97Å; D218-E221 VanDerWaalsContact O-N 3.16Å; D218-I222 WeakPolarHBondContact O-CG1 3.27Å; D218-I222 PolarHBondContact O-N 3.29Å; D218-I222 VanDerWaalsContact O-N 3.08Å
219L90.4Very high90.1Very high0 Ų044.4 Ų44.40%024%0.243CC..Hα-helixtrans-66.7-35.4-178.2-61.1-177.6000111.5L19 L28 I216 Q217 E221 I222 V227 W230 I231L19-L219 HydrophobicContact CD1-CD2 3.75Å; L19-L219 HydrophobicContact CD2-CD2 4.2Å; L28-L219 HydrophobicContact CB-CD2 4.06Å; L28-L219 HydrophobicContact CD1-CD2 3.95Å; L28-L219 HydrophobicContact CD1-CG 4.05Å; L28-L219 HydrophobicContact CG-CD2 4.46Å; I216-L219 HydrophobicContact CB-CB 4.42Å; I216-L219 HydrophobicContact CB-CD1 4.25Å; I216-L219 HydrophobicContact CG2-CD1 4.27Å; I216-L219 WeakPolarHBondContact O-CA 3.1Å; I216-L219 WeakPolarHBondContact O-CB 3.48Å; I216-L219 PolarHBondContact O-N 3.36Å; Q217-L219 VanDerWaalsContact C-N 3.27Å; Q217-L219 PolarHBondContact O-N 2.85Å; L219-E221 VanDerWaalsContact C-N 3.27Å; L219-E221 PolarHBondContact O-N 3.13Å; L219-I222 HydrophobicContact CD2-CD1 4.16Å; L219-V227 HydrophobicContact CB-CG2 3.92Å; L219-V227 HydrophobicContact CD2-CG2 4.04Å; L219-V227 VanDerWaalsContact O-CG1 3.32Å; L219-V227 WeakPolarHBondContact O-CG1 3.44Å; L219-V227 WeakPolarHBondContact O-CG2 3.25Å; L219-W230 HydrophobicContact CD1-CB 4.27Å; L219-I231 HydrophobicContact CB-CD1 4.19Å; L219-I231 HydrophobicContact CB-CG1 3.86Å; L219-I231 HydrophobicContact CD1-CG1 4.44Å
220T88.5Confident89.8Confident35 Ų3544.4 Ų44.422%0.21524%0.243CC..Hα-helixtrans-73.1-21.1176.161.80000113W202 I216 Q217 D218 I231W202-T220 HydrophobicContact CE3-CG2 3.97Å; W202-T220 HydrophobicContact CH2-CG2 4.15Å; W202-T220 HydrophobicContact CZ3-CG2 3.63Å; I216-T220 HydrophobicContact CD1-CG2 4.23Å; I216-T220 HydrophobicContact CG1-CG2 4.39Å; I216-T220 PolarHBondContact O-N 3.44Å; Q217-T220 PolarHBondContact O-N 2.81Å; Q217-T220 PolarHBondContact O-OG1 3.05Å; D218-T220 VanDerWaalsContact C-N 3.31Å; D218-T220 PolarHBondContact O-N 2.77Å; T220-I231 HydrophobicContact CG2-CD1 4.09Å
221E88.7Confident89.7Confident126 Ų12644.8 Ų44.859%0.58925%0.245SC*.Hα-helixtrans-94.2-20.5-177.2-70.6173.7172.600113.9Q217 D218 L219 G223Q217-E221 HydrophobicContact CG-CG 4.33Å; Q217-E221 WeakPolarHBondContact CG-OE1 3.24Å; Q217-E221 PolarHBondContact NE2-OE1 2.56Å; Q217-E221 WeakPolarHBondContact O-CG 3.35Å; Q217-E221 PolarHBondContact O-N 3.2Å; D218-E221 PolarHBondContact O-N 2.97Å; D218-E221 VanDerWaalsContact O-N 3.16Å; L219-E221 VanDerWaalsContact C-N 3.27Å; L219-E221 PolarHBondContact O-N 3.13Å; E221-G223 PolarHBondContact O-N 3.17Å; E221-G223 VanDerWaalsContact O-N 3.1Å
222I85.4Confident89.7Confident53 Ų5345 Ų4527%0.27225%0.246SC..SBendtrans-57.3-24.5177.7-78.7166.1000113.7L30 D218 L219 T224 V227L30-I222 HydrophobicContact CD1-CG2 4.18Å; D218-I222 WeakPolarHBondContact O-CG1 3.27Å; D218-I222 PolarHBondContact O-N 3.29Å; D218-I222 VanDerWaalsContact O-N 3.08Å; L219-I222 HydrophobicContact CD2-CD1 4.16Å; I222-T224 HydrophobicContact CG2-CG2 4.19Å; I222-T224 WeakPolarHBondContact CG2-OG1 3.34Å; I222-T224 PolarHBondContact O-N 3.17Å; I222-V227 HydrophobicContact CB-CG2 4.33Å; I222-V227 HydrophobicContact CD1-CG2 4.29Å; I222-V227 HydrophobicContact CG2-CB 4.37Å; I222-V227 HydrophobicContact CG2-CG2 4.35Å
223G77.3Confident89.7Confident69 Ų6945.6 Ų45.671%0.71125%0.25SC*.  trans71.5-16.9171.500000117.3E221E221-G223 PolarHBondContact O-N 3.17Å; E221-G223 VanDerWaalsContact O-N 3.1Å
224T83.4Confident89.7Confident63 Ų6341.8 Ų41.839%0.38723%0.233SC..  trans-79.6142.6179.864.90000112.9L30 I222 D226 V227L30-T224 WeakPolarHBondContact CD1-OG1 3.23Å; I222-T224 HydrophobicContact CG2-CG2 4.19Å; I222-T224 WeakPolarHBondContact CG2-OG1 3.34Å; I222-T224 PolarHBondContact O-N 3.17Å; T224-D226 VanDerWaalsContact C-N 3.29Å; T224-D226 PolarHBondContact O-N 3.31Å; T224-V227 WeakPolarHBondContact O-CB 3.38Å; T224-V227 VanDerWaalsContact O-CG1 3.23Å; T224-V227 WeakPolarHBondContact O-CG1 3.48Å; T224-V227 PolarHBondContact O-N 3.42Å; T224-V227 VanDerWaalsContact O-N 3.11Å
225P84.3Confident89.9Confident98 Ų9838 Ų3864%0.63622%0.219SC*.G310 helixtrans-64.8-23.7-175.526.1-35.4000115V227 N228P225-V227 PolarHBondContact O-N 3.48Å; P225-N228 VanDerWaalsContact O-CB 3.25Å; P225-N228 WeakPolarHBondContact O-CB 3.3Å; P225-N228 PolarHBondContact O-N 2.87Å; P225-N228 PolarHBondContact O-ND2 2.83Å
226D84.8Confident90Very high74 Ų7438.2 Ų38.240%0.39622%0.219SC..G310 helixtrans-67.9-18175.9-76.1-71.8000113.8R17 L30 T224 N228 F229R17-D226 IonicContact CZ-OD1 3.35Å; R17-D226 IonicContact NE-OD1 2.67Å; R17-D226 PolarHBondContact NE-OD1 2.84Å; R17-D226 IonicContact NH2-OD1 2.96Å; R17-D226 PolarHBondContact NH2-OD1 2.92Å; L30-D226 HydrophobicContact CD1-CB 4.17Å; T224-D226 VanDerWaalsContact C-N 3.29Å; T224-D226 PolarHBondContact O-N 3.31Å; D226-N228 PolarHBondContact O-N 3.46Å; D226-F229 PolarHBondContact O-N 2.87Å
227V88.6Confident90.1Very high2 Ų238.2 Ų38.21%0.01222%0.219CC..G310 helixtrans-67.6-24.2176.888.10000112.4L30 L219 I222 T224 P225 F229 W230 I231L30-V227 HydrophobicContact CD1-CB 3.76Å; L30-V227 HydrophobicContact CD1-CG2 4.02Å; L219-V227 HydrophobicContact CB-CG2 3.92Å; L219-V227 HydrophobicContact CD2-CG2 4.04Å; L219-V227 VanDerWaalsContact O-CG1 3.32Å; L219-V227 WeakPolarHBondContact O-CG1 3.44Å; L219-V227 WeakPolarHBondContact O-CG2 3.25Å; I222-V227 HydrophobicContact CB-CG2 4.33Å; I222-V227 HydrophobicContact CD1-CG2 4.29Å; I222-V227 HydrophobicContact CG2-CB 4.37Å; I222-V227 HydrophobicContact CG2-CG2 4.35Å; T224-V227 WeakPolarHBondContact O-CB 3.38Å; T224-V227 VanDerWaalsContact O-CG1 3.23Å; T224-V227 WeakPolarHBondContact O-CG1 3.48Å; T224-V227 PolarHBondContact O-N 3.42Å; T224-V227 VanDerWaalsContact O-N 3.11Å; P225-V227 PolarHBondContact O-N 3.48Å; V227-F229 PolarHBondContact O-N 3.2Å; V227-W230 PolarHBondContact O-N 3.01Å; V227-I231 HydrophobicContact CG1-CD1 3.92Å; V227-I231 HydrophobicContact CG2-CD1 4.46Å; V227-I231 PolarHBondContact O-N 3.11Å
228N90.3Very high90.4Very high51 Ų5135 Ų3527%0.27320%0.204SC..G310 helixtrans-56.4-26.3179-64-27.2000113.2P200 W202 P225 D226P200-N228 HydrophobicContact CB-CB 3.98Å; P200-N228 WeakPolarHBondContact CG-OD1 3.47Å; W202-N228 PolarHBondContact NE1-OD1 3.04Å; P225-N228 VanDerWaalsContact O-CB 3.25Å; P225-N228 WeakPolarHBondContact O-CB 3.3Å; P225-N228 PolarHBondContact O-N 2.87Å; P225-N228 PolarHBondContact O-ND2 2.83Å; D226-N228 PolarHBondContact O-N 3.46Å
229F89.2Confident90.8Very high79 Ų7933.3 Ų33.335%0.34620%0.195SC..G310 helixtrans-73-27.8177.8-177.8-97.3000113.4M1 Q14 D226 V227M1-F229 HydrophobicContact CE-CE1 4.39Å; Q14-F229 HydrophobicContact CB-CE1 4.08Å; Q14-F229 HydrophobicContact CB-CZ 4.39Å; Q14-F229 HydrophobicContact CG-CE1 4.2Å; Q14-F229 HydrophobicContact CG-CZ 3.98Å; D226-F229 PolarHBondContact O-N 2.87Å; V227-F229 PolarHBondContact O-N 3.2Å
230W91.6Very high91.1Very high1 Ų134.6 Ų34.60%0.00420%0.201CC..THydrogen-bonded Turntrans-94.6-15.6-174.7-61.396.9000113.2M1 L12 R17 L19 L30 V51 L219 V227 I232M1-W230 HydrophobicContact CE-CE3 4.22Å; M1-W230 HydrophobicContact CE-CZ3 4.1Å; M1-W230 HydrophobicContact CG-CZ3 4.18Å; M1-W230 HydrophobicContact SD-CE3 4.11Å; M1-W230 HydrophobicContact SD-CZ3 3.57Å; M1-W230 VanDerWaalsContact SD-CZ3 3.57Å; L12-W230 HydrophobicContact CB-CH2 3.88Å; L12-W230 HydrophobicContact CB-CZ3 3.65Å; L12-W230 HydrophobicContact CD2-CZ3 4.31Å; L12-W230 VanDerWaalsContact O-CH2 3.26Å; L12-W230 WeakPolarHBondContact O-CH2 3.44Å; R17-W230 HydrophobicContact CB-CZ2 4.12Å; L19-W230 HydrophobicContact CB-CD2 3.81Å; L19-W230 HydrophobicContact CB-CE3 3.94Å; L19-W230 HydrophobicContact CB-CG 4.44Å; L19-W230 HydrophobicContact CB-CH2 4Å; L19-W230 HydrophobicContact CB-CZ2 3.85Å; L19-W230 HydrophobicContact CB-CZ3 4.03Å; L19-W230 HydrophobicContact CD2-CB 4.31Å; L19-W230 HydrophobicContact CD2-CD2 3.97Å; L19-W230 HydrophobicContact CD2-CE3 3.85Å; L19-W230 HydrophobicContact CD2-CG 4.18Å; L19-W230 HydrophobicContact CG-CD2 4.46Å; L30-W230 VanDerWaalsContact CD2-CD1 3.49Å; L30-W230 HydrophobicContact CD2-CG 4.43Å; V51-W230 HydrophobicContact CG2-CE3 4.29Å; L219-W230 HydrophobicContact CD1-CB 4.27Å; V227-W230 PolarHBondContact O-N 3.01Å; W230-I232 PolarHBondContact O-N 3.15Å
231I94Very high91.6Very high10 Ų1033.7 Ų33.75%0.05120%0.195CC..  trans-86.8110.6-179.9-65166.6000109.7W202 F210 I216 L219 T220 V227W202-I231 HydrophobicContact CB-CB 4.38Å; W202-I231 HydrophobicContact CB-CG2 3.39Å; W202-I231 HydrophobicContact CD2-CD1 3.81Å; W202-I231 HydrophobicContact CD2-CG2 3.96Å; W202-I231 VanDerWaalsContact CE2-CD1 3.43Å; W202-I231 HydrophobicContact CE3-CD1 4.37Å; W202-I231 HydrophobicContact CG-CB 4.04Å; W202-I231 HydrophobicContact CG-CD1 4.18Å; W202-I231 HydrophobicContact CG-CG2 3.43Å; W202-I231 VanDerWaalsContact CG-CG2 3.43Å; W202-I231 HydrophobicContact CH2-CD1 4.28Å; W202-I231 HydrophobicContact CZ2-CD1 3.7Å; F210-I231 HydrophobicContact CZ-CG2 4.06Å; I216-I231 HydrophobicContact CD1-CB 4.42Å; I216-I231 HydrophobicContact CD1-CG1 4.35Å; I216-I231 HydrophobicContact CD1-CG2 3.6Å; L219-I231 HydrophobicContact CB-CD1 4.19Å; L219-I231 HydrophobicContact CB-CG1 3.86Å; L219-I231 HydrophobicContact CD1-CG1 4.44Å; T220-I231 HydrophobicContact CG2-CD1 4.09Å; V227-I231 HydrophobicContact CG1-CD1 3.92Å; V227-I231 HydrophobicContact CG2-CD1 4.46Å; V227-I231 PolarHBondContact O-N 3.11Å
232I94.6Very high91.9Very high6 Ų630.9 Ų30.93%0.03118%0.182CC..  trans-107.2110.8175.3-58.5176.1000108.7I68 Y178 L180 N212 W230 M234I68-I232 HydrophobicContact CD1-CD1 4.27Å; Y178-I232 HydrophobicContact CD2-CG2 3.38Å; Y178-I232 HydrophobicContact CE2-CD1 4.47Å; Y178-I232 HydrophobicContact CE2-CG2 4.07Å; Y178-I232 HydrophobicContact CG-CG2 3.71Å; L180-I232 HydrophobicContact CD2-CD1 4.28Å; L180-I232 HydrophobicContact CD2-CG1 4.1Å; L180-I232 HydrophobicContact CD2-CG2 4.43Å; N212-I232 PolarHBondContact ND2-O 2.83Å; N212-I232 PolarHBondContact OD1-O 3.08Å; W230-I232 PolarHBondContact O-N 3.15Å; I232-M234 HydrophobicContact CG2-CG 4.21Å; I232-M234 PolarHBondContact O-N 3.19Å
233P95.6Very high92.3Very high13 Ų1333.4 Ų33.48%0.08419%0.192CC..  trans-67.8122.3170.1-20.934.3000111.6Y178 L201 W202 V205 F210Y178-P233 WeakPolarHBondContact CB-O 3.28Å; L201-P233 HydrophobicContact CD2-CG 4.42Å; W202-P233 HydrophobicContact CB-CG 3.75Å; V205-P233 HydrophobicContact CG1-CB 3.92Å; V205-P233 HydrophobicContact CG1-CG 3.97Å; F210-P233 HydrophobicContact CD2-CB 4.24Å; F210-P233 HydrophobicContact CE2-CB 4.04Å; F210-P233 HydrophobicContact CE2-CG 4.46Å; F210-P233 HydrophobicContact CZ-CB 4.34Å; F210-P233 HydrophobicContact CZ-CG 4.32Å
234M95.8Very high93Very high2 Ų230.2 Ų30.21%0.0116%0.159CC..EExtended strand (participates in β ladder)trans-116.2131.8178.6-53.1-175.876.700111I52 V86 F176 Y177 Y178 W211 N212 I232I52-M234 HydrophobicContact CB-SD 4.33Å; I52-M234 HydrophobicContact CD1-CE 4.36Å; I52-M234 HydrophobicContact CD1-SD 4.42Å; I52-M234 HydrophobicContact CG1-CE 4.49Å; I52-M234 HydrophobicContact CG1-SD 4.03Å; I52-M234 HydrophobicContact CG2-SD 3.92Å; V86-M234 HydrophobicContact CB-CE 4.45Å; V86-M234 HydrophobicContact CG2-CE 3.44Å; V86-M234 VanDerWaalsContact CG2-CE 3.44Å; F176-M234 HydrophobicContact CB-CE 4.08Å; Y177-M234 WeakPolarHBondContact O-CA 3.41Å; Y178-M234 HydrophobicContact CD1-CE 4.35Å; W211-M234 VanDerWaalsContact CB-O 3.29Å; W211-M234 WeakPolarHBondContact CB-O 3.38Å; W211-M234 PolarHBondContact N-O 3.11Å; N212-M234 HydrophobicContact CB-SD 4.49Å; N212-M234 WeakPolarHBondContact OD1-CB 3.23Å; N212-M234 PolarHBondContact OD1-N 3.35Å; I232-M234 HydrophobicContact CG2-CG 4.21Å; I232-M234 PolarHBondContact O-N 3.19Å
235I97.6Very high93.3Very high1 Ų130.2 Ų30.21%0.00516%0.159CC..EExtended strand (participates in β ladder)trans-89.8146.7164.962.5166.1000110F176 Y177 L184 T185 F209 V239 I281 R283F176-I235 WeakPolarHBondContact CA-O 3.25Å; Y177-I235 PolarHBondContact N-O 2.82Å; Y177-I235 VanDerWaalsContact N-O 3.08Å; Y177-I235 PolarHBondContact O-N 2.78Å; L184-I235 HydrophobicContact CB-CD1 4.14Å; L184-I235 HydrophobicContact CB-CG1 4.32Å; L184-I235 HydrophobicContact CB-CG2 4.18Å; T185-I235 HydrophobicContact CG2-CG2 3.84Å; F209-I235 HydrophobicContact CB-CG2 4.28Å; I235-V239 HydrophobicContact CD1-CG2 4.1Å; I235-I281 HydrophobicContact CD1-CG2 4.22Å; I235-R283 HydrophobicContact CD1-CG 4.17Å; I235-R283 HydrophobicContact CG2-CG 4.31Å
236Q96.5Very high93.3Very high5 Ų525.9 Ų25.92%0.02313%0.131CC..EExtended strand (participates in β ladder)trans-95.5136155.9-172.2176.498.500108.8S175 F176 W211 R284 Q515S175-Q236 CarbonylContact O-C 3.57Å; S175-Q236 WeakPolarHBondContact O-CA 3.46Å; F176-Q236 HydrophobicContact CD1-CB 4.03Å; F176-Q236 HydrophobicContact CD1-CG 4.29Å; F176-Q236 HydrophobicContact CE1-CB 3.82Å; F176-Q236 HydrophobicContact CE1-CG 3.98Å; F176-Q236 VanDerWaalsContact CE1-NE2 3.33Å; F176-Q236 HydrophobicContact CZ-CG 4.36Å; W211-Q236 HydrophobicContact CB-CB 4.5Å; W211-Q236 HydrophobicContact CD2-CB 3.56Å; W211-Q236 HydrophobicContact CE3-CB 3.49Å; W211-Q236 VanDerWaalsContact CE3-CB 3.49Å; W211-Q236 HydrophobicContact CG-CB 4.02Å; W211-Q236 HydrophobicContact CH2-CB 4.34Å; W211-Q236 VanDerWaalsContact CH2-OE1 3.29Å; W211-Q236 HydrophobicContact CZ2-CB 4.45Å; W211-Q236 HydrophobicContact CZ3-CB 3.89Å; Q236-R284 WeakPolarHBondContact O-CB 3.48Å; Q236-R284 PolarHBondContact O-N 2.9Å; Q236-R284 VanDerWaalsContact OE1-CD 3.25Å; Q236-Q515 HydrophobicContact CG-CG 4.44Å
237G95.4Very high93.3Very high0 Ų023.8 Ų23.80%012%0.119CC..EExtended strand (participates in β ladder)trans153.3-121.717700000112.5S175 S282 Q515S175-G237 PolarHBondContact O-N 3.01Å; G237-S282 CarbonylContact C-O 3.51Å; G237-S282 VanDerWaalsContact CA-O 3.27Å; G237-S282 WeakPolarHBondContact CA-O 3.48Å; G237-Q515 PolarHBondContact O-NE2 3.12Å
238F96.9Very high92.8Very high8 Ų827.6 Ų27.64%0.03513%0.134CC..EExtended strand (participates in β ladder)trans-148.9140.2-176.2176.9-103.1000110.8Q240 L280 I281 S282 N507 N508 S511 I512F238-Q240 HydrophobicContact CE1-CB 3.7Å; F238-Q240 HydrophobicContact CE2-CB 4.27Å; F238-Q240 HydrophobicContact CZ-CB 3.41Å; F238-Q240 VanDerWaalsContact CZ-CB 3.41Å; F238-Q240 HydrophobicContact CZ-CG 4.46Å; F238-L280 HydrophobicContact CE1-CB 4.46Å; F238-L280 HydrophobicContact CE1-CD2 4.29Å; F238-L280 HydrophobicContact CE1-CG 4.38Å; F238-I281 CarbonylContact O-C 3.53Å; F238-I281 WeakPolarHBondContact O-CA 3.16Å; F238-S282 PolarHBondContact N-O 3.01Å; F238-S282 PolarHBondContact O-N 2.8Å; F238-N507 HydrophobicContact CE2-CB 3.8Å; F238-N507 HydrophobicContact CZ-CB 3.59Å; F238-N508 HydrophobicContact CD1-CB 3.59Å; F238-N508 HydrophobicContact CE1-CB 3.68Å; F238-N508 HydrophobicContact CG-CB 4.21Å; F238-N508 HydrophobicContact CZ-CB 4.35Å; F238-S511 VanDerWaalsContact CD2-OG 3.31Å; F238-S511 WeakPolarHBondContact CD2-OG 3.15Å; F238-I512 HydrophobicContact CB-CD1 4.34Å
239V98Very high91.8Very high3 Ų330.5 Ų30.52%0.01815%0.154CC..EExtended strand (participates in β ladder)trans-136.5132.9162.5-172.10000108.4V74 V83 Y177 I235 I241 L280 I281V74-V239 HydrophobicContact CG1-CB 4.36Å; V74-V239 HydrophobicContact CG1-CG1 4.17Å; V74-V239 WeakPolarHBondContact CG1-O 3.21Å; V83-V239 HydrophobicContact CG1-CB 4.34Å; V83-V239 HydrophobicContact CG1-CG1 4.11Å; V83-V239 HydrophobicContact CG1-CG2 4.37Å; Y177-V239 HydrophobicContact CD1-CB 3.69Å; Y177-V239 HydrophobicContact CD1-CG2 3.78Å; Y177-V239 HydrophobicContact CD2-CG2 4.45Å; Y177-V239 HydrophobicContact CE1-CB 3.73Å; Y177-V239 HydrophobicContact CE1-CG2 4.23Å; Y177-V239 WeakPolarHBondContact CE1-O 3.4Å; Y177-V239 HydrophobicContact CG-CB 4.28Å; Y177-V239 HydrophobicContact CG-CG2 3.87Å; Y177-V239 PolarHBondContact OH-N 2.97Å; Y177-V239 PolarHBondContact OH-O 2.9Å; I235-V239 HydrophobicContact CD1-CG2 4.1Å; V239-I241 HydrophobicContact CG1-CD1 4.34Å; V239-I241 HydrophobicContact CG1-CG1 4.05Å; V239-L280 WeakPolarHBondContact CA-O 3.38Å; V239-I281 HydrophobicContact CG1-CG1 4.13Å; V239-I281 HydrophobicContact CG2-CG1 4.36Å; V239-I281 HydrophobicContact CG2-CG2 4.33Å
240Q97.4Very high90.4Very high27 Ų2730.8 Ų30.813%0.12616%0.156CC..EExtended strand (participates in β ladder)trans-138.3139.1162.2-176.6173.8-9.200107.9F238 E242 A279 L280 M504 N507F238-Q240 HydrophobicContact CE1-CB 3.7Å; F238-Q240 HydrophobicContact CE2-CB 4.27Å; F238-Q240 HydrophobicContact CZ-CB 3.41Å; F238-Q240 VanDerWaalsContact CZ-CB 3.41Å; F238-Q240 HydrophobicContact CZ-CG 4.46Å; Q240-E242 HydrophobicContact CG-CG 4.27Å; Q240-E242 PolarHBondContact NE2-OE1 3.36Å; Q240-A279 WeakPolarHBondContact O-CA 3.49Å; Q240-L280 PolarHBondContact N-O 3.34Å; Q240-L280 PolarHBondContact O-N 2.8Å; Q240-M504 HydrophobicContact CB-CE 4.39Å; Q240-M504 HydrophobicContact CG-CE 4.29Å; Q240-M504 HydrophobicContact CG-CG 4.3Å; Q240-M504 WeakPolarHBondContact O-CE 3.5Å; Q240-N507 PolarHBondContact OE1-ND2 2.9Å
241I97.4Very high88.3Confident17 Ų1734.5 Ų34.59%0.08718%0.183CC..EExtended strand (participates in β ladder)trans-127.4128.4-178.5-54.9171000106.2L77 V83 V239 L277 V278 A279L77-I241 HydrophobicContact CD2-CD1 3.76Å; L77-I241 HydrophobicContact CD2-CG1 4.21Å; L77-I241 HydrophobicContact CG-CD1 3.92Å; V83-I241 HydrophobicContact CB-CD1 4.31Å; V83-I241 HydrophobicContact CG2-CD1 4.17Å; V239-I241 HydrophobicContact CG1-CD1 4.34Å; V239-I241 HydrophobicContact CG1-CG1 4.05Å; I241-L277 HydrophobicContact CG2-CD1 3.86Å; I241-L277 HydrophobicContact CG2-CD2 4.04Å; I241-L277 HydrophobicContact CG2-CG 3.93Å; I241-V278 WeakPolarHBondContact CA-O 3.42Å; I241-A279 HydrophobicContact CB-CB 4.47Å; I241-A279 HydrophobicContact CG1-CB 3.91Å; I241-A279 HydrophobicContact CG2-CB 4.39Å
242E96.1Very high86.2Confident67 Ų6737.1 Ų37.131%0.31320%0.202SC..EExtended strand (participates in β ladder)trans-133.4149.5179.9-62.5-66.2163.200109.2Q240 V278 I500 M504Q240-E242 HydrophobicContact CG-CG 4.27Å; Q240-E242 PolarHBondContact NE2-OE1 3.36Å; E242-V278 HydrophobicContact CB-CG1 4.03Å; E242-V278 PolarHBondContact N-O 2.93Å; E242-V278 PolarHBondContact O-N 2.94Å; E242-I500 HydrophobicContact CB-CG2 4.13Å; E242-I500 HydrophobicContact CG-CG2 3.88Å; E242-M504 HydrophobicContact CB-CE 4.24Å; E242-M504 HydrophobicContact CB-SD 3.99Å; E242-M504 HydrophobicContact CG-CE 3.9Å; E242-M504 HydrophobicContact CG-CG 3.92Å; E242-M504 HydrophobicContact CG-SD 3.64Å
243E93.8Very high84.1Confident105 Ų10540.8 Ų40.849%0.49122%0.221SC..EExtended strand (participates in β ladder)trans-106.1127.4170.1-158.7-165.6166.700109.4R275E243-R275 IonicContact OE1-CZ 3.3Å; E243-R275 IonicContact OE1-NE 2.73Å; E243-R275 PolarHBondContact OE1-NE 3.25Å; E243-R275 IonicContact OE1-NH2 2.78Å; E243-R275 PolarHBondContact OE1-NH2 3.07Å; E243-R275 IonicContact OE2-CZ 3.44Å; E243-R275 IonicContact OE2-NE 3.48Å; E243-R275 IonicContact OE2-NH2 3.32Å; E243-R275 PolarHBondContact OE2-NH2 3.1Å
244L91.9Very high82Confident2 Ų246.7 Ų46.71%0.0125%0.252CS..EExtended strand (participates in β ladder)trans-113.8141.5-174.4-66.7-176.2000111.1R275 F276 V278 C497 I500L244-R275 CarbonylContact O-C 3.42Å; L244-R275 VanDerWaalsContact O-CA 3.28Å; L244-R275 WeakPolarHBondContact O-CA 3.47Å; L244-F276 HydrophobicContact CB-CD1 4Å; L244-F276 HydrophobicContact CB-CD2 4.38Å; L244-F276 HydrophobicContact CB-CE1 3.61Å; L244-F276 HydrophobicContact CB-CE2 4.04Å; L244-F276 HydrophobicContact CB-CG 4.38Å; L244-F276 HydrophobicContact CB-CZ 3.64Å; L244-F276 HydrophobicContact CD1-CE1 4.28Å; L244-F276 HydrophobicContact CD1-CE2 3.67Å; L244-F276 HydrophobicContact CD1-CZ 3.46Å; L244-F276 VanDerWaalsContact CD1-CZ 3.46Å; L244-F276 HydrophobicContact CG-CE2 4.33Å; L244-F276 HydrophobicContact CG-CZ 4.16Å; L244-F276 PolarHBondContact N-O 3Å; L244-F276 PolarHBondContact O-N 3.09Å; L244-V278 HydrophobicContact CD1-CB 4.5Å; L244-V278 HydrophobicContact CD1-CG1 3.6Å; L244-V278 HydrophobicContact CG-CG1 3.88Å; L244-C497 HydrophobicContact CD1-CB 4.25Å; L244-I500 HydrophobicContact CD2-CB 3.82Å; L244-I500 HydrophobicContact CD2-CD1 3.47Å; L244-I500 VanDerWaalsContact CD2-CD1 3.47Å; L244-I500 HydrophobicContact CD2-CG1 4.24Å; L244-I500 HydrophobicContact CD2-CG2 3.78Å
245V88.9Confident79.6Confident64 Ų6453.5 Ų53.539%0.38828%0.284SS..EExtended strand (participates in β ladder)trans-113.5119178.8-173.70000108.1N247 H273 R275 C497V245-N247 PolarHBondContact O-N 3.49Å; V245-N247 VanDerWaalsContact O-N 3.12Å; V245-H273 HydrophobicContact CG1-CB 3.56Å; V245-R275 HydrophobicContact CG2-CG 4.24Å; V245-C497 PolarHBondContact O-SG 3.49Å
246V85.8Confident77.2Confident6 Ų660.4 Ų60.44%0.03631%0.314CS..  trans-78.698.5176.3178.10000108.9Y248 P274 F276 V486 P494V246-Y248 HydrophobicContact CG1-CD2 4.02Å; V246-Y248 HydrophobicContact CG1-CE2 3.45Å; V246-Y248 VanDerWaalsContact CG1-CE2 3.45Å; V246-P274 HydrophobicContact CB-CG 4.15Å; V246-P274 PolarHBondContact N-O 3.46Å; V246-F276 HydrophobicContact CG2-CD1 3.92Å; V246-F276 HydrophobicContact CG2-CE1 3.66Å; V246-V486 HydrophobicContact CG2-CG1 3.75Å; V246-P494 HydrophobicContact CG1-CG 3.91Å
247N83.5Confident74.6Confident30 Ų3064.1 Ų64.116%0.1634%0.34CS..  trans-124.7127.1172.9-169.2-9.2000110.9V245 T249 H273 P494V245-N247 PolarHBondContact O-N 3.49Å; V245-N247 VanDerWaalsContact O-N 3.12Å; N247-T249 PolarHBondContact ND2-OG1 3.19Å; N247-T249 WeakPolarHBondContact OD1-CB 3.24Å; N247-T249 PolarHBondContact OD1-N 3.22Å; N247-T249 PolarHBondContact OD1-OG1 3.41Å; N247-H273 VanDerWaalsContact CG-NE2 3.26Å; N247-H273 PolarHBondContact ND2-NE2 3.16Å; N247-H273 PolarHBondContact OD1-CD2 3.46Å; N247-H273 PolarHBondContact OD1-NE2 3.29Å; N247-P494 WeakPolarHBondContact O-CB 3.49Å
248Y78.1Confident72.3Confident82 Ų8269 Ų6932%0.32238%0.375SS..SBendtrans-106.1-11.1177.1-70.6-78.8000113.8V246 M487 P488 Q491 P492 P494V246-Y248 HydrophobicContact CG1-CD2 4.02Å; V246-Y248 HydrophobicContact CG1-CE2 3.45Å; V246-Y248 VanDerWaalsContact CG1-CE2 3.45Å; Y248-M487 WeakPolarHBondContact OH-CG 3.48Å; Y248-P488 HydrophobicContact CE2-CG 4.33Å; Y248-Q491 HydrophobicContact CE1-CB 3.94Å; Y248-Q491 VanDerWaalsContact CE2-OE1 3.29Å; Y248-Q491 VanDerWaalsContact CZ-OE1 3.3Å; Y248-P492 VanDerWaalsContact CE1-O 3.26Å; Y248-P492 WeakPolarHBondContact CE1-O 3.31Å; Y248-P492 PolarHBondContact OH-O 3.15Å; Y248-P494 HydrophobicContact CD1-CG 4.16Å; Y248-P494 HydrophobicContact CD2-CG 4.41Å; Y248-P494 HydrophobicContact CE1-CB 4.47Å; Y248-P494 HydrophobicContact CE1-CG 3.75Å; Y248-P494 HydrophobicContact CE2-CG 4.02Å; Y248-P494 HydrophobicContact CG-CG 4.49Å
249T70.6Confident70.3Confident113 Ų11374.6 Ų74.669%0.69341%0.412SS*.SBendtrans-77.7-24.1179.165.80000112.7N247 S251N247-T249 PolarHBondContact ND2-OG1 3.19Å; N247-T249 WeakPolarHBondContact OD1-CB 3.24Å; N247-T249 PolarHBondContact OD1-N 3.22Å; N247-T249 PolarHBondContact OD1-OG1 3.41Å; T249-S251 PolarHBondContact O-N 3.5Å; T249-S251 VanDerWaalsContact O-N 3.1Å
250E59.2Low67.9Low85 Ų8583.5 Ų83.540%0.39745%0.453SS..  trans-79.290.9174.4-70.5-168.911300111.4K496E250-K496 IonicContact OE1-NZ 3.93Å; E250-K496 PolarHBondContact OE1-NZ 3.14Å; E250-K496 WeakPolarHBondContact OE2-CD 3.38Å; E250-K496 VanDerWaalsContact OE2-CE 3.29Å; E250-K496 WeakPolarHBondContact OE2-CE 3.4Å; E250-K496 IonicContact OE2-NZ 3.39Å; E250-K496 PolarHBondContact OE2-NZ 3.02Å
251S47.6Very low65.3Low79 Ų7988.3 Ų88.355%0.55249%0.485SS*.  trans-57.3157.9156.957.10000110.9T249 D253T249-S251 PolarHBondContact O-N 3.5Å; T249-S251 VanDerWaalsContact O-N 3.1Å; S251-D253 PolarHBondContact O-N 3.31Å
252S48.8Very low62.8Low65 Ų6592.7 Ų92.746%0.45551%0.514SS..  trans-55.9130-176.442.90000112.2D254 E255S252-D254 PolarHBondContact O-N 3.14Å; S252-E255 PolarHBondContact O-N 2.95Å
253D50.2Low60.3Low82 Ų8295.4 Ų95.444%0.43954%0.538SS..G310 helixtrans-58.8-13.4-177.3-68.7-67.5000114.2S251 E255 K256 K496S251-D253 PolarHBondContact O-N 3.31Å; D253-E255 PolarHBondContact O-N 3.19Å; D253-K256 PolarHBondContact O-N 3.31Å; D253-K256 IonicContact OD1-NZ 2.8Å; D253-K256 PolarHBondContact OD1-NZ 2.71Å; D253-K496 IonicContact OD2-NZ 2.77Å; D253-K496 PolarHBondContact OD2-NZ 3.37Å
254D51.8Low57.8Low138 Ų13899.8 Ų99.874%0.73856%0.558SS**G310 helixtrans-60.7-24.7171.5-57.2-71.5000113.8S252 K256S252-D254 PolarHBondContact O-N 3.14Å; D254-K256 VanDerWaalsContact C-N 3.35Å
255E47.1Very low55.3Low144 Ų144108.5 Ų108.567%0.67360%0.599SS**G310 helixtrans-75.5-16.9177-81.4-79.210500113.6S252 D253 S257S252-E255 PolarHBondContact O-N 2.95Å; D253-E255 PolarHBondContact O-N 3.19Å; E255-S257 PolarHBondContact O-N 3.04Å
256K46.5Very low53.1Low147 Ų147110.5 Ų110.564%0.63962%0.615SS**THydrogen-bonded Turntrans-79.247-173.7-67.4174.6-176.71600113.4D253 D254D253-K256 PolarHBondContact O-N 3.31Å; D253-K256 IonicContact OD1-NZ 2.8Å; D253-K256 PolarHBondContact OD1-NZ 2.71Å; D254-K256 VanDerWaalsContact C-N 3.35Å
257S42.4Very low50.9Low82 Ų82116.4 Ų116.457%0.57365%0.652SS**THydrogen-bonded Turntrans-118.48.5178.566.90000115E255E255-S257 PolarHBondContact O-N 3.04Å
258S46.4Very low49.2Very low103 Ų103120.7 Ų120.772%0.7268%0.683SS**  trans-113.6108.8172.4-67.40000110.8E260S258-E260 PolarHBondContact O-N 3.39Å
259P54.3Low47.5Very low126 Ų126122.7 Ų122.782%0.81870%0.703SS**  trans-96.872.4-174.737.2-34.3000112.6
260E47.4Very low46Very low189 Ų189124.1 Ų124.188%0.88371%0.707SS**  trans-156.664175-127.2161.1-120.700114.7S258S258-E260 PolarHBondContact O-N 3.39Å
261T42.9Very low45.5Very low129 Ų129125.9 Ų125.979%0.79172%0.719SS**  trans-146135.2162.7-26.80000109.6
262P46.2Very low46.1Very low109 Ų109129 Ų12971%0.70873%0.728SS**  trans-62.4150.2171.9-21.133.2000111.3Q264P262-Q264 PolarHBondContact O-N 3.38Å; P262-Q264 VanDerWaalsContact O-N 3.1Å
263P43.4Very low47.2Very low124 Ų124128.8 Ų128.881%0.80572%0.719SS**  trans-64.4113.5170.627.7-32.9000109E265P263-E265 PolarHBondContact O-N 3.05Å
264Q40.7Very low48.9Very low196 Ų196127.5 Ų127.592%0.91672%0.716SS**  trans-64.5132.6166.7-103.6179-35.400108.8P262P262-Q264 PolarHBondContact O-N 3.38Å; P262-Q264 VanDerWaalsContact O-N 3.1Å
265E38.8Very low50.7Low185 Ų185127.4 Ų127.486%0.86471%0.705SS**  trans-64.4143.5-179.2-63.6-178.1133.400110.8P263 T267P263-E265 PolarHBondContact O-N 3.05Å; E265-T267 PolarHBondContact O-N 2.71Å
266S42.5Very low52.9Low106 Ų106120.7 Ų120.774%0.74167%0.673SS**  trans-65105.8-178.551.40000111.5C268S266-C268 PolarHBondContact O-N 2.74Å; S266-C268 PolarHBondContact O-SG 2.78Å; S266-C268 VanDerWaalsContact O-SG 3.34Å
267T39.8Very low55.3Low130 Ų130115.2 Ų115.280%0.79865%0.651SS**  trans-58.4122.7169.234.90000110.3E265 V269E265-T267 PolarHBondContact O-N 2.71Å; T267-V269 PolarHBondContact O-N 2.93Å
268C48.1Very low57.9Low120 Ų120111.4 Ų111.481%0.81162%0.624SS**SBendtrans-86.2101.6-165.5-58.50000113.5S266S266-C268 PolarHBondContact O-N 2.74Å; S266-C268 PolarHBondContact O-SG 2.78Å; S266-C268 VanDerWaalsContact O-SG 3.34Å
269V42.1Very low60.3Low125 Ų125106.5 Ų106.576%0.75859%0.59SS**SBendtrans-140.4159.1141.4-170.10000106.5T267 D271T267-V269 PolarHBondContact O-N 2.93Å; V269-D271 PolarHBondContact O-N 2.79Å
270D40.7Very low62.4Low142 Ų142100.6 Ų100.676%0.75955%0.552SS**  trans-6593.8172-65.4-70.2000111.1I272D270-I272 HydrophobicContact CB-CD1 4.39Å; D270-I272 HydrophobicContact CB-CG1 4.12Å; D270-I272 PolarHBondContact O-N 3.29Å
271D47.6Very low64.8Low123 Ų12391.6 Ų91.666%0.65851%0.509SS*.  trans-7168.2173.7-81.5-29.1000111.3V269 H273V269-D271 PolarHBondContact O-N 2.79Å; D271-H273 PolarHBondContact O-N 3.2Å; D271-H273 PolarHBondContact O-ND1 2.94Å
272I60.9Low67.5Low144 Ų14485.4 Ų85.474%0.73847%0.472SS*.  trans-71.980.2172.3-54.3178.1000108.3D270D270-I272 HydrophobicContact CB-CD1 4.39Å; D270-I272 HydrophobicContact CB-CG1 4.12Å; D270-I272 PolarHBondContact O-N 3.29Å
273H72.1Confident69.9Low60 Ų6080.2 Ų80.228%0.27844%0.438SS..PPolyproline II helixtrans-52.3121170.7-70.679000109.5V245 N247 D271 R275V245-H273 HydrophobicContact CG1-CB 3.56Å; N247-H273 VanDerWaalsContact CG-NE2 3.26Å; N247-H273 PolarHBondContact ND2-NE2 3.16Å; N247-H273 PolarHBondContact OD1-CD2 3.46Å; N247-H273 PolarHBondContact OD1-NE2 3.29Å; D271-H273 PolarHBondContact O-N 3.2Å; D271-H273 PolarHBondContact O-ND1 2.94Å; H273-R275 WeakPolarHBondContact O-CG 3.12Å; H273-R275 PolarHBondContact O-N 2.91Å
274P84.3Confident72.4Confident55 Ų5574.5 Ų74.536%0.35740%0.4SS..PPolyproline II helixtrans-66.4130-168.320.3-27.3000111.2V246 V486V246-P274 HydrophobicContact CB-CG 4.15Å; V246-P274 PolarHBondContact N-O 3.46Å; P274-V486 HydrophobicContact CB-CG1 4.25Å; P274-V486 HydrophobicContact CB-CG2 4.43Å
275R90.1Very high75Confident137 Ų13765.5 Ų65.552%0.51736%0.359SS..EExtended strand (participates in β ladder)trans-103.5144.4-175.2-56.7176.366.6149.7-4110.1E243 L244 V245 H273E243-R275 IonicContact OE1-CZ 3.3Å; E243-R275 IonicContact OE1-NE 2.73Å; E243-R275 PolarHBondContact OE1-NE 3.25Å; E243-R275 IonicContact OE1-NH2 2.78Å; E243-R275 PolarHBondContact OE1-NH2 3.07Å; E243-R275 IonicContact OE2-CZ 3.44Å; E243-R275 IonicContact OE2-NE 3.48Å; E243-R275 IonicContact OE2-NH2 3.32Å; E243-R275 PolarHBondContact OE2-NH2 3.1Å; L244-R275 CarbonylContact O-C 3.42Å; L244-R275 VanDerWaalsContact O-CA 3.28Å; L244-R275 WeakPolarHBondContact O-CA 3.47Å; V245-R275 HydrophobicContact CG2-CG 4.24Å; H273-R275 WeakPolarHBondContact O-CG 3.12Å; H273-R275 PolarHBondContact O-N 2.91Å
276F93.9Very high77.6Confident2 Ų258 Ų581%0.00932%0.323CS..EExtended strand (participates in β ladder)trans-142.3141.1172.270.1-84.6000111L244 V246 V278 I314 H315 V316 M477 L481 V486 L493L244-F276 HydrophobicContact CB-CD1 4Å; L244-F276 HydrophobicContact CB-CD2 4.38Å; L244-F276 HydrophobicContact CB-CE1 3.61Å; L244-F276 HydrophobicContact CB-CE2 4.04Å; L244-F276 HydrophobicContact CB-CG 4.38Å; L244-F276 HydrophobicContact CB-CZ 3.64Å; L244-F276 HydrophobicContact CD1-CE1 4.28Å; L244-F276 HydrophobicContact CD1-CE2 3.67Å; L244-F276 HydrophobicContact CD1-CZ 3.46Å; L244-F276 VanDerWaalsContact CD1-CZ 3.46Å; L244-F276 HydrophobicContact CG-CE2 4.33Å; L244-F276 HydrophobicContact CG-CZ 4.16Å; L244-F276 PolarHBondContact N-O 3Å; L244-F276 PolarHBondContact O-N 3.09Å; V246-F276 HydrophobicContact CG2-CD1 3.92Å; V246-F276 HydrophobicContact CG2-CE1 3.66Å; F276-V278 HydrophobicContact CD2-CB 4.46Å; F276-V278 HydrophobicContact CE2-CB 4.25Å; F276-I314 HydrophobicContact CD2-CD1 3.99Å; F276-I314 HydrophobicContact CD2-CG2 4.14Å; F276-I314 HydrophobicContact CE2-CD1 3.87Å; F276-H315 WeakPolarHBondContact CA-O 3.45Å; F276-V316 HydrophobicContact CB-CG2 3.45Å; F276-V316 VanDerWaalsContact CB-CG2 3.45Å; F276-M477 HydrophobicContact CE2-SD 4.38Å; F276-L481 HydrophobicContact CB-CD2 4.25Å; F276-L481 HydrophobicContact CD1-CD2 3.85Å; F276-L481 HydrophobicContact CD2-CD2 3.82Å; F276-L481 HydrophobicContact CE1-CD1 3.95Å; F276-L481 HydrophobicContact CE1-CD2 4.04Å; F276-L481 HydrophobicContact CE2-CD1 4.04Å; F276-L481 HydrophobicContact CE2-CD2 3.99Å; F276-L481 HydrophobicContact CG-CD2 3.73Å; F276-L481 HydrophobicContact CZ-CD1 3.62Å; F276-L481 HydrophobicContact CZ-CD2 4.09Å; F276-V486 HydrophobicContact CD1-CG1 4.08Å; F276-L493 HydrophobicContact CZ-CD1 4.45Å
277L96.1Very high80Confident32 Ų3255.4 Ų55.417%0.16830%0.299CS..EExtended strand (participates in β ladder)trans-85.2133.9170.6177.5152000108.9I241 A279 I314 H315I241-L277 HydrophobicContact CG2-CD1 3.86Å; I241-L277 HydrophobicContact CG2-CD2 4.04Å; I241-L277 HydrophobicContact CG2-CG 3.93Å; L277-A279 HydrophobicContact CD2-CB 4.36Å; L277-I314 WeakPolarHBondContact O-CA 3.43Å; L277-H315 HydrophobicContact CB-CB 4.25Å; L277-H315 HydrophobicContact CD2-CB 4.22Å; L277-H315 PolarHBondContact N-O 2.97Å; L277-H315 PolarHBondContact O-N 3.08Å
278V96.8Very high82.5Confident2 Ų252 Ų521%0.01227%0.271CS..EExtended strand (participates in β ladder)trans-117.6130.6169.658.60000109.5I241 E242 L244 F276 L313 I314 M504I241-V278 WeakPolarHBondContact CA-O 3.42Å; E242-V278 HydrophobicContact CB-CG1 4.03Å; E242-V278 PolarHBondContact N-O 2.93Å; E242-V278 PolarHBondContact O-N 2.94Å; L244-V278 HydrophobicContact CD1-CB 4.5Å; L244-V278 HydrophobicContact CD1-CG1 3.6Å; L244-V278 HydrophobicContact CG-CG1 3.88Å; F276-V278 HydrophobicContact CD2-CB 4.46Å; F276-V278 HydrophobicContact CE2-CB 4.25Å; V278-L313 WeakPolarHBondContact CA-O 3.34Å; V278-I314 HydrophobicContact CB-CD1 3.87Å; V278-I314 HydrophobicContact CG2-CD1 3.72Å; V278-M504 HydrophobicContact CG1-CE 4.04Å; V278-M504 HydrophobicContact CG1-SD 3.72Å; V278-M504 HydrophobicContact CG2-CE 4.28Å; V278-M504 HydrophobicContact CG2-SD 4.39Å
279A98Very high84.5Confident0 Ų046.5 Ų46.50%023%0.234CC..EExtended strand (participates in β ladder)trans-122.5139170.100000110.2L77 Q240 I241 L277 Q312 L313L77-A279 HydrophobicContact CD2-CB 3.71Å; Q240-A279 WeakPolarHBondContact O-CA 3.49Å; I241-A279 HydrophobicContact CB-CB 4.47Å; I241-A279 HydrophobicContact CG1-CB 3.91Å; I241-A279 HydrophobicContact CG2-CB 4.39Å; L277-A279 HydrophobicContact CD2-CB 4.36Å; A279-Q312 WeakPolarHBondContact O-CA 3.47Å; A279-L313 HydrophobicContact CB-CB 4.12Å; A279-L313 HydrophobicContact CB-CD1 4.33Å; A279-L313 HydrophobicContact CB-CG 4.48Å; A279-L313 PolarHBondContact N-O 2.9Å; A279-L313 PolarHBondContact O-N 2.88Å
280L98.4Very high86.7Confident2 Ų240.5 Ų40.51%0.0120%0.198CC..EExtended strand (participates in β ladder)trans-118.8106.6175-176.559.8000108.6F238 V239 Q240 T310 M504 W505 N508F238-L280 HydrophobicContact CE1-CB 4.46Å; F238-L280 HydrophobicContact CE1-CD2 4.29Å; F238-L280 HydrophobicContact CE1-CG 4.38Å; V239-L280 WeakPolarHBondContact CA-O 3.38Å; Q240-L280 PolarHBondContact N-O 3.34Å; Q240-L280 PolarHBondContact O-N 2.8Å; L280-T310 HydrophobicContact CD1-CG2 3.78Å; L280-M504 HydrophobicContact CB-CE 4.07Å; L280-M504 HydrophobicContact CD2-CB 4.26Å; L280-W505 HydrophobicContact CD1-CD2 4.4Å; L280-W505 HydrophobicContact CD1-CH2 4.05Å; L280-W505 HydrophobicContact CD1-CZ2 3.6Å; L280-W505 HydrophobicContact CD2-CD2 3.73Å; L280-W505 HydrophobicContact CD2-CE3 4.27Å; L280-W505 HydrophobicContact CD2-CG 3.85Å; L280-W505 HydrophobicContact CD2-CZ2 4.43Å; L280-N508 HydrophobicContact CD2-CB 3.78Å; L280-N508 HydrophobicContact CG-CB 4.48Å
281I98.5Very high88.8Confident0 Ų033.8 Ų33.80%016%0.162CC..EExtended strand (participates in β ladder)trans-107.6126-178.7-59.1170.6000107.8L77 L184 I235 F238 V239 R283 T310 E311 L313L77-I281 HydrophobicContact CD1-CD1 4.27Å; L184-I281 HydrophobicContact CD2-CD1 4.28Å; I235-I281 HydrophobicContact CD1-CG2 4.22Å; F238-I281 CarbonylContact O-C 3.53Å; F238-I281 WeakPolarHBondContact O-CA 3.16Å; V239-I281 HydrophobicContact CG1-CG1 4.13Å; V239-I281 HydrophobicContact CG2-CG1 4.36Å; V239-I281 HydrophobicContact CG2-CG2 4.33Å; I281-R283 HydrophobicContact CG2-CG 4.13Å; I281-T310 CarbonylContact O-C 3.5Å; I281-T310 WeakPolarHBondContact O-CA 3.48Å; I281-E311 HydrophobicContact CB-CB 4.49Å; I281-E311 PolarHBondContact N-O 3.39Å; I281-E311 PolarHBondContact O-N 3.1Å; I281-L313 HydrophobicContact CD1-CD1 3.95Å
282S98.1Very high90.4Very high0 Ų029.2 Ų29.20%014%0.136CC..EExtended strand (participates in β ladder)trans-120.2128167-68.10000109.7G237 F238 E309 T310 R327 N508G237-S282 CarbonylContact C-O 3.51Å; G237-S282 VanDerWaalsContact CA-O 3.27Å; G237-S282 WeakPolarHBondContact CA-O 3.48Å; F238-S282 PolarHBondContact N-O 3.01Å; F238-S282 PolarHBondContact O-N 2.8Å; S282-E309 CarbonylContact C-O 3.57Å; S282-E309 WeakPolarHBondContact CA-O 3.42Å; S282-T310 WeakPolarHBondContact OG-CG2 3.41Å; S282-T310 PolarHBondContact OG-OG1 3.48Å; S282-R327 PolarHBondContact OG-NH2 3.23Å; S282-N508 PolarHBondContact OG-ND2 3.12Å; S282-N508 PolarHBondContact OG-OD1 2.87Å; S282-N508 VanDerWaalsContact OG-OD1 3.05Å
283R97.4Very high91.2Very high0 Ų024 Ų240%011%0.107CC..EExtended strand (participates in β ladder)trans-112.6118.7179.7-56.6174.1-102.2-841109.3L184 T185 N186 F209 I235 I281 V308 E309 E311L184-R283 VanDerWaalsContact O-CD 3.23Å; L184-R283 WeakPolarHBondContact O-CD 3.46Å; L184-R283 PolarHBondContact O-NH1 2.99Å; L184-R283 VanDerWaalsContact O-NH1 3.07Å; T185-R283 WeakPolarHBondContact O-CD 3.43Å; T185-R283 PolarHBondContact O-NE 2.68Å; N186-R283 PolarHBondContact O-NH1 3.17Å; F209-R283 HydrophobicContact CB-CB 4.11Å; F209-R283 HydrophobicContact CD1-CB 3.4Å; F209-R283 HydrophobicContact CD2-CB 4.15Å; F209-R283 HydrophobicContact CE1-CB 3.75Å; F209-R283 VanDerWaalsContact CE1-O 3.24Å; F209-R283 WeakPolarHBondContact CE1-O 3.48Å; F209-R283 HydrophobicContact CE2-CB 4.44Å; F209-R283 HydrophobicContact CG-CB 3.61Å; F209-R283 HydrophobicContact CG-CG 4.32Å; F209-R283 HydrophobicContact CZ-CB 4.26Å; I235-R283 HydrophobicContact CD1-CG 4.17Å; I235-R283 HydrophobicContact CG2-CG 4.31Å; I281-R283 HydrophobicContact CG2-CG 4.13Å; R283-V308 CarbonylContact O-C 3.55Å; R283-V308 VanDerWaalsContact O-CA 3.23Å; R283-V308 WeakPolarHBondContact O-CA 3.48Å; R283-V308 WeakPolarHBondContact O-CG1 3.46Å; R283-E309 IonicContact CZ-OE1 2.74Å; R283-E309 PolarHBondContact N-O 2.91Å; R283-E309 IonicContact NE-OE1 3.65Å; R283-E309 PolarHBondContact NE-OE1 2.85Å; R283-E309 IonicContact NH2-OE1 2.76Å; R283-E309 PolarHBondContact NH2-OE1 2.88Å; R283-E309 PolarHBondContact O-N 2.78Å; R283-E311 IonicContact CZ-OE2 3.73Å; R283-E311 VanDerWaalsContact CZ-OE2 3.23Å; R283-E311 IonicContact NH1-OE2 3.12Å; R283-E311 PolarHBondContact NH1-OE2 3.3Å; R283-E311 IonicContact NH2-OE1 2.68Å; R283-E311 IonicContact NH2-OE2 3.19Å; R283-E311 PolarHBondContact NH2-OE2 2.81Å
284R95.5Very high91.7Very high4 Ų425.8 Ų25.82%0.01511%0.114CC..EExtended strand (participates in β ladder)trans-89.2132173.7-172.3-169.1-172.6179.311.8109.6W211 Q236 G290 N306 V308 Q515W211-R284 HydrophobicContact CZ3-CB 4.24Å; W211-R284 HydrophobicContact CZ3-CG 4.08Å; Q236-R284 WeakPolarHBondContact O-CB 3.48Å; Q236-R284 PolarHBondContact O-N 2.9Å; Q236-R284 VanDerWaalsContact OE1-CD 3.25Å; R284-G290 PolarHBondContact NH2-O 3.27Å; R284-N306 PolarHBondContact NE-OD1 3.44Å; R284-N306 PolarHBondContact NH2-OD1 3.32Å; R284-V308 HydrophobicContact CB-CG2 4.19Å; R284-V308 HydrophobicContact CG-CG2 4.14Å; R284-Q515 PolarHBondContact NH1-O 3.08Å; R284-Q515 PolarHBondContact NH2-O 3.33Å; R284-Q515 VanDerWaalsContact NH2-O 3.11Å
285S95.6Very high91.8Very high6 Ų626.3 Ų26.34%0.04211%0.109CC..  trans-66.6136.8179.5-176.10000112R208 W211 H287 Y307R208-S285 CarbonylContact O-C 3.56Å; R208-S285 WeakPolarHBondContact O-CA 3.47Å; R208-S285 PolarHBondContact O-OG 2.96Å; W211-S285 VanDerWaalsContact CZ3-O 3.31Å; W211-S285 WeakPolarHBondContact CZ3-O 3.37Å; S285-H287 PolarHBondContact O-N 3.5Å; S285-H287 PolarHBondContact OG-N 3.3Å; S285-H287 VanDerWaalsContact OG-N 3.16Å; S285-Y307 PolarHBondContact N-O 3.08Å
286R93.6Very high91.8Very high27 Ų2720.3 Ų20.310%0.1029%0.086CC..SBendtrans-60.2-34.4168.569.5-177.9-80.595.313110.9D207 R208 F210 W211D207-R286 WeakPolarHBondContact O-CD 3.47Å; R208-R286 WeakPolarHBondContact O-CG 3.42Å; R208-R286 PolarHBondContact O-N 2.98Å; F210-R286 PolarHBondContact O-NH1 3.33Å; W211-R286 HydrophobicContact CE3-CB 4.37Å; W211-R286 PolarHBondContact O-NH1 3.16Å; W211-R286 VanDerWaalsContact O-NH1 3.14Å
287H93Very high91.7Very high52 Ų5220.2 Ų20.224%0.2419%0.086CC..THydrogen-bonded Turntrans-76.1129.7-173.2-60.1-50.7000111.1D207 S285 A289 N303D207-H287 IonicContact OD2-CE1 2.86Å; D207-H287 PolarHBondContact OD2-CE1 3.42Å; D207-H287 VanDerWaalsContact OD2-CE1 3.32Å; D207-H287 IonicContact OD2-NE2 2.66Å; D207-H287 PolarHBondContact OD2-NE2 3.25Å; S285-H287 PolarHBondContact O-N 3.5Å; S285-H287 PolarHBondContact OG-N 3.3Å; S285-H287 VanDerWaalsContact OG-N 3.16Å; H287-A289 PolarHBondContact O-N 2.91Å; H287-A289 VanDerWaalsContact O-N 3.11Å; H287-N303 HydrophobicContact CB-CB 3.98Å; H287-N303 VanDerWaalsContact CB-OD1 3.31Å; H287-N303 WeakPolarHBondContact CB-OD1 3.48Å
288R91.3Very high91.6Very high59 Ų5918.7 Ų18.722%0.2238%0.078CC..THydrogen-bonded Turntrans50.730.3-175.5-156.3177174.871.5-5.5114.4R296 G297 V298 N303 A305R288-R296 PolarHBondContact NE-O 3.45Å; R288-R296 PolarHBondContact NH2-O 3.39Å; R288-G297 WeakPolarHBondContact CD-O 3.46Å; R288-G297 PolarHBondContact NE-O 2.88Å; R288-V298 PolarHBondContact NE-O 3.23Å; R288-V298 PolarHBondContact NH2-O 3.03Å; R288-V298 VanDerWaalsContact NH2-O 3.08Å; R288-N303 HydrophobicContact CB-CB 4.14Å; R288-N303 WeakPolarHBondContact CD-O 3.46Å; R288-A305 HydrophobicContact CG-CB 3.96Å; R288-A305 WeakPolarHBondContact O-CA 3.49Å
289A90.6Very high91.4Very high4 Ų420 Ų203%0.0338%0.084CC..  trans-60.8141.8174.800000112.7W211 H287 Q559 I562W211-A289 HydrophobicContact CH2-CB 3.5Å; W211-A289 VanDerWaalsContact CH2-CB 3.5Å; W211-A289 HydrophobicContact CZ2-CB 4.24Å; W211-A289 HydrophobicContact CZ3-CB 4.17Å; H287-A289 PolarHBondContact O-N 2.91Å; H287-A289 VanDerWaalsContact O-N 3.11Å; A289-Q559 PolarHBondContact O-NE2 3.28Å; A289-Q559 VanDerWaalsContact O-NE2 3.08Å; A289-I562 HydrophobicContact CB-CG2 3.82Å
290G87.4Confident91.1Very high0 Ų027.6 Ų27.60%012%0.117CC..  trans173.7178.4171.600000118.2R284 N306R284-G290 PolarHBondContact NH2-O 3.27Å; G290-N306 PolarHBondContact N-OD1 3.11Å; G290-N306 VanDerWaalsContact O-CG 3.27Å; G290-N306 PolarHBondContact O-ND2 2.95Å; G290-N306 PolarHBondContact O-OD1 2.85Å
291M86.3Confident90.8Very high0 Ų033.6 Ų33.60%015%0.15CC..  trans-75.7150.8-178-60.3-55.1-64.400112.1Y293 K294 R295 Y516 D555 R558 Q559 I562M291-Y293 VanDerWaalsContact C-N 3.31Å; M291-Y293 PolarHBondContact O-N 2.83Å; M291-K294 HydrophobicContact CB-CB 4.19Å; M291-K294 HydrophobicContact CB-CG 4.08Å; M291-K294 PolarHBondContact O-N 3.08Å; M291-R295 PolarHBondContact O-N 2.81Å; M291-Y516 WeakPolarHBondContact CE-O 3.36Å; M291-D555 HydrophobicContact CB-CB 3.89Å; M291-D555 HydrophobicContact CE-CB 4.47Å; M291-D555 WeakPolarHBondContact CE-OD1 3.3Å; M291-D555 HydrophobicContact CG-CB 4.06Å; M291-R558 HydrophobicContact CG-CB 4.26Å; M291-R558 HydrophobicContact CG-CG 4.41Å; M291-R558 HydrophobicContact SD-CB 4.25Å; M291-R558 HydrophobicContact SD-CG 3.8Å; M291-Q559 HydrophobicContact CG-CB 4.49Å; M291-I562 HydrophobicContact SD-CD1 4.33Å
292R79.8Confident90.5Very high28 Ų2833.8 Ų33.811%0.10615%0.152CC..THydrogen-bonded Turntrans-42.5-46.4-169.2-179.8173.9-179.8-175.51.7115.9R296 D460 Y516R292-R296 VanDerWaalsContact O-CZ 3.28Å; R292-R296 PolarHBondContact O-NE 3.5Å; R292-R296 PolarHBondContact O-NH2 2.83Å; R292-D460 IonicContact CZ-OD1 2.73Å; R292-D460 IonicContact NE-OD1 3.15Å; R292-D460 PolarHBondContact NE-OD1 3Å; R292-D460 PolarHBondContact NH2-O 3.12Å; R292-D460 IonicContact NH2-OD1 2.68Å; R292-D460 PolarHBondContact NH2-OD1 3.48Å; R292-D460 IonicContact NH2-OD2 3.2Å; R292-Y516 HydrophobicContact CB-CD1 4.31Å; R292-Y516 HydrophobicContact CB-CE1 3.9Å; R292-Y516 HydrophobicContact CB-CE2 4.13Å; R292-Y516 HydrophobicContact CG-CE1 3.77Å; R292-Y516 PolarHBondContact N-O 3.5Å
293Y78.4Confident90.4Very high35 Ų3535.4 Ų35.414%0.13716%0.16CC..THydrogen-bonded Turntrans-105.87.9-178.1-60.1-75000113.5M291 Q336 P343 N551M291-Y293 VanDerWaalsContact C-N 3.31Å; M291-Y293 PolarHBondContact O-N 2.83Å; Y293-Q336 HydrophobicContact CD1-CB 3.8Å; Y293-Q336 HydrophobicContact CE1-CB 4.24Å; Y293-P343 HydrophobicContact CD1-CG 3.89Å; Y293-P343 HydrophobicContact CE1-CG 3.85Å; Y293-N551 HydrophobicContact CD2-CB 4.2Å; Y293-N551 WeakPolarHBondContact CD2-ND2 3.45Å; Y293-N551 WeakPolarHBondContact CD2-OD1 3.27Å
294K82Confident90.3Very high96 Ų9635.5 Ų35.542%0.41716%0.161SC..THydrogen-bonded Turntrans-105.1-36.3179.1-61.5-63.4-174.7174.10113.1M291 D555 Q559M291-K294 HydrophobicContact CB-CB 4.19Å; M291-K294 HydrophobicContact CB-CG 4.08Å; M291-K294 PolarHBondContact O-N 3.08Å; K294-D555 HydrophobicContact CG-CB 4.41Å; K294-Q559 HydrophobicContact CB-CB 4.34Å; K294-Q559 HydrophobicContact CB-CG 4.15Å; K294-Q559 HydrophobicContact CG-CB 4.35Å
295R86.5Confident90.1Very high67 Ų6735.4 Ų35.425%0.25316%0.161SC..SBendtrans-130.6120.6175.4-57.4-68.3-168.51782.6110.8M291 A305 D563M291-R295 PolarHBondContact O-N 2.81Å; R295-A305 HydrophobicContact CB-CB 4.14Å; R295-D563 IonicContact CZ-OD1 2.74Å; R295-D563 IonicContact CZ-OD2 2.87Å; R295-D563 IonicContact NE-OD1 3.22Å; R295-D563 IonicContact NH2-OD1 2.61Å; R295-D563 PolarHBondContact NH2-OD1 3.33Å; R295-D563 IonicContact NH2-OD2 2.63Å; R295-D563 PolarHBondContact NH2-OD2 3.25Å
296R90.8Very high89.9Confident10 Ų1035.9 Ų35.94%0.03816%0.163CC..  trans-143.8164.9177-71.5-169.8174.2-91.910.2110.5R288 R292 W334 M459 D460 Y516R288-R296 PolarHBondContact NE-O 3.45Å; R288-R296 PolarHBondContact NH2-O 3.39Å; R292-R296 VanDerWaalsContact O-CZ 3.28Å; R292-R296 PolarHBondContact O-NE 3.5Å; R292-R296 PolarHBondContact O-NH2 2.83Å; R296-W334 HydrophobicContact CB-CD2 4.28Å; R296-W334 HydrophobicContact CB-CZ2 4.42Å; R296-W334 WeakPolarHBondContact CB-O 3.41Å; R296-M459 PolarHBondContact NH1-O 3.35Å; R296-D460 IonicContact CZ-OD1 2.78Å; R296-D460 IonicContact NH2-OD1 2.85Å; R296-D460 PolarHBondContact NH2-OD1 2.95Å; R296-D460 IonicContact NH2-OD2 3.96Å; R296-Y516 PolarHBondContact NH1-OH 2.7Å
297G92.3Very high89.9Confident0 Ų035 Ų350%016%0.16CC..SBendtrans67.9-168.8177.800000114.4R288 A305 S329 V330 V332 W334R288-G297 WeakPolarHBondContact CD-O 3.46Å; R288-G297 PolarHBondContact NE-O 2.88Å; G297-A305 PolarHBondContact O-N 2.63Å; G297-S329 PolarHBondContact N-OG 3.19Å; G297-V330 WeakPolarHBondContact CA-O 3.41Å; G297-V332 CarbonylContact C-O 3.59Å; G297-V332 WeakPolarHBondContact CA-O 3.32Å; G297-W334 VanDerWaalsContact CA-CD1 3.42Å
298V94.4Very high90.1Very high0 Ų032.7 Ų32.70%015%0.15CC..BIsolated β-bridgetrans-86.6159.1175.576.10000112R288 G302 N303 V304 V332 F333R288-V298 PolarHBondContact NE-O 3.23Å; R288-V298 PolarHBondContact NH2-O 3.03Å; R288-V298 VanDerWaalsContact NH2-O 3.08Å; V298-G302 VanDerWaalsContact CG2-C 3.46Å; V298-G302 WeakPolarHBondContact CG2-O 3.37Å; V298-N303 CarbonylContact C-O 3.39Å; V298-N303 WeakPolarHBondContact CA-O 3.48Å; V298-V304 HydrophobicContact CB-CG1 4.46Å; V298-V304 HydrophobicContact CG2-CG1 4.39Å; V298-V332 PolarHBondContact N-O 2.82Å; V298-F333 HydrophobicContact CG1-CD1 4.35Å; V298-F333 HydrophobicContact CG1-CD2 3.87Å; V298-F333 HydrophobicContact CG1-CE1 4.06Å; V298-F333 HydrophobicContact CG1-CE2 3.54Å; V298-F333 HydrophobicContact CG1-CG 4.25Å; V298-F333 HydrophobicContact CG1-CZ 3.64Å; V298-F333 WeakPolarHBondContact O-CE1 3.27Å
299D92.4Very high90.4Very high29 Ų2929.9 Ų29.916%0.15514%0.139CC..  trans-100.8-169.6166.165.520.9000113.2N301 G302 N303 F333D299-N301 PolarHBondContact O-N 3.1Å; D299-N301 WeakPolarHBondContact OD1-CA 3.46Å; D299-N301 WeakPolarHBondContact OD1-CB 3.48Å; D299-N301 PolarHBondContact OD1-N 3.32Å; D299-G302 PolarHBondContact OD1-N 2.84Å; D299-N303 PolarHBondContact N-O 3.23Å; D299-N303 PolarHBondContact OD1-N 2.96Å; D299-N303 PolarHBondContact OD1-ND2 2.91Å; D299-N303 WeakPolarHBondContact OD2-CB 3.44Å; D299-N303 PolarHBondContact OD2-ND2 3.15Å; D299-F333 WeakPolarHBondContact O-CZ 3.43Å
300K91.3Very high90.8Very high160 Ų16029.8 Ų29.870%0.69614%0.138SC*.THydrogen-bonded Turntrans-72.6-8.4177.7-65.8-172.1-179.6-175.90114Y357K300-Y357 VanDerWaalsContact CA-CE1 3.49Å; K300-Y357 HydrophobicContact CB-CE1 4.03Å; K300-Y357 HydrophobicContact CG-CE1 4.41Å; K300-Y357 VanDerWaalsContact O-CD1 3.32Å; K300-Y357 WeakPolarHBondContact O-CD1 3.43Å; K300-Y357 VanDerWaalsContact O-CE1 3.24Å; K300-Y357 WeakPolarHBondContact O-CE1 3.48Å
301N91.7Very high91.3Very high128 Ų12829.8 Ų29.868%0.68414%0.138SC*.THydrogen-bonded Turntrans-113.37.9-174.6-57.814.5000111.3D299D299-N301 PolarHBondContact O-N 3.1Å; D299-N301 WeakPolarHBondContact OD1-CA 3.46Å; D299-N301 WeakPolarHBondContact OD1-CB 3.48Å; D299-N301 PolarHBondContact OD1-N 3.32Å
302G93.1Very high91.9Very high5 Ų530 Ų305%0.05214%0.139CC..SBendtrans83.5-1.3-176.700000115V298 D299 V304 H361V298-G302 VanDerWaalsContact CG2-C 3.46Å; V298-G302 WeakPolarHBondContact CG2-O 3.37Å; D299-G302 PolarHBondContact OD1-N 2.84Å; G302-V304 PolarHBondContact O-N 2.8Å; G302-H361 VanDerWaalsContact O-CB 3.3Å; G302-H361 WeakPolarHBondContact O-CB 3.3Å; G302-H361 PolarHBondContact O-ND1 3.41Å
303N94.9Very high92.7Very high33 Ų3328.8 Ų28.818%0.17613%0.134CC..PPolyproline II helixtrans-75.6128.5-179.6-55.5-77.1000110.8H287 R288 V298 D299H287-N303 HydrophobicContact CB-CB 3.98Å; H287-N303 VanDerWaalsContact CB-OD1 3.31Å; H287-N303 WeakPolarHBondContact CB-OD1 3.48Å; R288-N303 HydrophobicContact CB-CB 4.14Å; R288-N303 WeakPolarHBondContact CD-O 3.46Å; V298-N303 CarbonylContact C-O 3.39Å; V298-N303 WeakPolarHBondContact CA-O 3.48Å; D299-N303 PolarHBondContact N-O 3.23Å; D299-N303 PolarHBondContact OD1-N 2.96Å; D299-N303 PolarHBondContact OD1-ND2 2.91Å; D299-N303 WeakPolarHBondContact OD2-CB 3.44Å; D299-N303 PolarHBondContact OD2-ND2 3.15Å
304V94.4Very high93.6Very high3 Ų327.1 Ų27.12%0.01813%0.128CC..BIsolated β-bridgetrans-86.2140.2170.7-64.60000111.9V298 G302 N306 Y307 P331V298-V304 HydrophobicContact CB-CG1 4.46Å; V298-V304 HydrophobicContact CG2-CG1 4.39Å; G302-V304 PolarHBondContact O-N 2.8Å; V304-N306 PolarHBondContact O-N 2.98Å; V304-Y307 HydrophobicContact CG2-CD2 3.77Å; V304-Y307 HydrophobicContact CG2-CG 4.37Å; V304-P331 HydrophobicContact CG1-CB 3.55Å
305A92.1Very high94.3Very high1 Ų124.5 Ų24.51%0.00812%0.117CC..THydrogen-bonded Turntrans-60.5132.2179.200000110.8R288 R295 G297 Y307 S329R288-A305 HydrophobicContact CG-CB 3.96Å; R288-A305 WeakPolarHBondContact O-CA 3.49Å; R295-A305 HydrophobicContact CB-CB 4.14Å; G297-A305 PolarHBondContact O-N 2.63Å; A305-Y307 VanDerWaalsContact C-N 3.34Å; A305-Y307 PolarHBondContact O-N 2.77Å; A305-S329 VanDerWaalsContact O-CB 3.27Å; A305-S329 WeakPolarHBondContact O-CB 3.37Å; A305-S329 PolarHBondContact O-N 2.76Å
306N90.7Very high94.6Very high17 Ų1721.7 Ų21.79%0.09111%0.107CC..THydrogen-bonded Turntrans57.541.7174.3-58.8-65000114.7R284 G290 V304 Y516R284-N306 PolarHBondContact NE-OD1 3.44Å; R284-N306 PolarHBondContact NH2-OD1 3.32Å; G290-N306 PolarHBondContact N-OD1 3.11Å; G290-N306 VanDerWaalsContact O-CG 3.27Å; G290-N306 PolarHBondContact O-ND2 2.95Å; G290-N306 PolarHBondContact O-OD1 2.85Å; V304-N306 PolarHBondContact O-N 2.98Å; N306-Y516 HydrophobicContact CB-CD2 4.12Å; N306-Y516 HydrophobicContact CB-CE2 4.21Å; N306-Y516 WeakPolarHBondContact ND2-CE2 3.46Å
307Y95Very high94.5Very high8 Ų828.8 Ų28.83%0.03114%0.141CC..  trans-57.7135164.7-169.9-98000111F209 S285 V304 A305 T326 R327 Q365 Y369F209-Y307 HydrophobicContact CE1-CD1 4.3Å; F209-Y307 HydrophobicContact CZ-CD1 4.21Å; F209-Y307 HydrophobicContact CZ-CE1 4.03Å; S285-Y307 PolarHBondContact N-O 3.08Å; V304-Y307 HydrophobicContact CG2-CD2 3.77Å; V304-Y307 HydrophobicContact CG2-CG 4.37Å; A305-Y307 VanDerWaalsContact C-N 3.34Å; A305-Y307 PolarHBondContact O-N 2.77Å; Y307-T326 HydrophobicContact CE1-CG2 4.45Å; Y307-T326 HydrophobicContact CE2-CG2 4.4Å; Y307-T326 VanDerWaalsContact OH-CG2 3.31Å; Y307-T326 WeakPolarHBondContact OH-CG2 3.19Å; Y307-R327 CarbonylContact C-O 3.49Å; Y307-R327 WeakPolarHBondContact CA-O 3.3Å; Y307-Q365 VanDerWaalsContact CE2-OE1 3.32Å; Y307-Q365 VanDerWaalsContact OH-CD 3.28Å; Y307-Q365 PolarHBondContact OH-NE2 3.03Å; Y307-Q365 PolarHBondContact OH-OE1 3.45Å; Y307-Y369 VanDerWaalsContact OH-CE2 3.24Å; Y307-Y369 WeakPolarHBondContact OH-CE2 3.37Å; Y307-Y369 PolarHBondContact OH-OH 2.78Å
308V96.3Very high94.4Very high4 Ų433 Ų332%0.02416%0.163CC..EExtended strand (participates in β ladder)trans-136.5127174.8179.70000109R283 R284 T326 R327 I512R283-V308 CarbonylContact O-C 3.55Å; R283-V308 VanDerWaalsContact O-CA 3.23Å; R283-V308 WeakPolarHBondContact O-CA 3.48Å; R283-V308 WeakPolarHBondContact O-CG1 3.46Å; R284-V308 HydrophobicContact CB-CG2 4.19Å; R284-V308 HydrophobicContact CG-CG2 4.14Å; V308-T326 WeakPolarHBondContact O-CA 3.48Å; V308-R327 HydrophobicContact CB-CG 3.85Å; V308-R327 HydrophobicContact CG1-CG 4.49Å; V308-R327 PolarHBondContact N-O 2.83Å; V308-R327 PolarHBondContact O-N 2.82Å; V308-I512 HydrophobicContact CG2-CG2 4.16Å
309E97.8Very high94.4Very high0 Ų035.8 Ų35.80%018%0.176CC..EExtended strand (participates in β ladder)trans-92.1127165.3-173.1179.182.600108.4R190 R208 F209 S282 R283 V324 T326 Y369R190-E309 IonicContact CZ-OE1 2.73Å; R190-E309 IonicContact CZ-OE2 3.1Å; R190-E309 IonicContact NH1-OE1 3.53Å; R190-E309 PolarHBondContact NH1-OE1 2.89Å; R190-E309 IonicContact NH1-OE2 3.35Å; R190-E309 PolarHBondContact NH1-OE2 2.81Å; R190-E309 IonicContact NH2-OE1 3.63Å; R190-E309 PolarHBondContact NH2-OE1 2.89Å; R190-E309 IonicContact NH2-OE2 3.22Å; R190-E309 PolarHBondContact NH2-OE2 2.91Å; R208-E309 IonicContact NH2-OE2 2.65Å; F209-E309 HydrophobicContact CE1-CB 4.26Å; F209-E309 HydrophobicContact CE2-CB 4.14Å; F209-E309 HydrophobicContact CZ-CB 3.56Å; S282-E309 CarbonylContact C-O 3.57Å; S282-E309 WeakPolarHBondContact CA-O 3.42Å; R283-E309 IonicContact CZ-OE1 2.74Å; R283-E309 PolarHBondContact N-O 2.91Å; R283-E309 IonicContact NE-OE1 3.65Å; R283-E309 PolarHBondContact NE-OE1 2.85Å; R283-E309 IonicContact NH2-OE1 2.76Å; R283-E309 PolarHBondContact NH2-OE1 2.88Å; R283-E309 PolarHBondContact O-N 2.78Å; E309-V324 HydrophobicContact CG-CG1 3.47Å; E309-V324 VanDerWaalsContact CG-CG1 3.47Å; E309-T326 HydrophobicContact CG-CG2 4.41Å; E309-Y369 VanDerWaalsContact OE2-CE1 3.27Å; E309-Y369 WeakPolarHBondContact OE2-CE1 3.43Å; E309-Y369 VanDerWaalsContact OE2-CZ 3.32Å; E309-Y369 PolarHBondContact OE2-OH 3.2Å
310T98.3Very high94.7Very high2 Ų235.5 Ų35.51%0.01218%0.175CC..EExtended strand (participates in β ladder)trans-112.2117.2175.8-530000108.1L280 I281 S282 Q325 R327 Q469 W505L280-T310 HydrophobicContact CD1-CG2 3.78Å; I281-T310 CarbonylContact O-C 3.5Å; I281-T310 WeakPolarHBondContact O-CA 3.48Å; S282-T310 WeakPolarHBondContact OG-CG2 3.41Å; S282-T310 PolarHBondContact OG-OG1 3.48Å; T310-Q325 PolarHBondContact N-O 3.01Å; T310-Q325 PolarHBondContact O-N 3.33Å; T310-R327 PolarHBondContact OG1-NE 2.91Å; T310-R327 PolarHBondContact OG1-NH2 2.92Å; T310-R327 VanDerWaalsContact OG1-NH2 3.15Å; T310-Q469 PolarHBondContact OG1-OE1 2.86Å; T310-W505 HydrophobicContact CG2-CH2 3.49Å; T310-W505 VanDerWaalsContact CG2-CH2 3.49Å; T310-W505 HydrophobicContact CG2-CZ2 4.3Å; T310-W505 HydrophobicContact CG2-CZ3 3.89Å
311E98.6Very high95Very high0 Ų027.9 Ų27.90%014%0.142CC..EExtended strand (participates in β ladder)trans-111.4128.6177.3175.1175.6-135.900109.9S187 V188 I281 R283 L313 S322 F323 V324S187-E311 WeakPolarHBondContact CA-OE1 3.45Å; S187-E311 WeakPolarHBondContact CB-OE1 3.3Å; V188-E311 PolarHBondContact N-OE1 2.95Å; I281-E311 HydrophobicContact CB-CB 4.49Å; I281-E311 PolarHBondContact N-O 3.39Å; I281-E311 PolarHBondContact O-N 3.1Å; R283-E311 IonicContact CZ-OE2 3.73Å; R283-E311 VanDerWaalsContact CZ-OE2 3.23Å; R283-E311 IonicContact NH1-OE2 3.12Å; R283-E311 PolarHBondContact NH1-OE2 3.3Å; R283-E311 IonicContact NH2-OE1 2.68Å; R283-E311 IonicContact NH2-OE2 3.19Å; R283-E311 PolarHBondContact NH2-OE2 2.81Å; E311-L313 HydrophobicContact CG-CD2 3.64Å; E311-L313 HydrophobicContact CG-CG 4.18Å; E311-S322 PolarHBondContact OE1-OG 2.99Å; E311-F323 WeakPolarHBondContact CA-O 3.37Å; E311-V324 HydrophobicContact CB-CG2 4.25Å; E311-V324 HydrophobicContact CG-CG2 4.21Å
312Q98.2Very high95.2Very high4 Ų421.8 Ų21.82%0.01911%0.11CC..EExtended strand (participates in β ladder)trans-102.4127.2166.8178.4-179.116.600108.7A279 S322 F323 A473 M477A279-Q312 WeakPolarHBondContact O-CA 3.47Å; Q312-S322 WeakPolarHBondContact O-CA 3.47Å; Q312-F323 PolarHBondContact N-O 2.83Å; Q312-F323 PolarHBondContact O-N 2.9Å; Q312-A473 PolarHBondContact OE1-O 2.8Å; Q312-M477 PolarHBondContact NE2-SD 2.85Å
313L97.4Very high95.5Very high2 Ų221.6 Ų21.61%0.0111%0.108CC..EExtended strand (participates in β ladder)trans-106.9139.2171.3-54.1-178.2000110.2L77 V188 V278 A279 I281 E311 L321L77-L313 HydrophobicContact CD2-CD1 4.05Å; V188-L313 HydrophobicContact CB-CD2 4.38Å; V188-L313 HydrophobicContact CG2-CD1 4.21Å; V188-L313 HydrophobicContact CG2-CD2 3.57Å; V278-L313 WeakPolarHBondContact CA-O 3.34Å; A279-L313 HydrophobicContact CB-CB 4.12Å; A279-L313 HydrophobicContact CB-CD1 4.33Å; A279-L313 HydrophobicContact CB-CG 4.48Å; A279-L313 PolarHBondContact N-O 2.9Å; A279-L313 PolarHBondContact O-N 2.88Å; I281-L313 HydrophobicContact CD1-CD1 3.95Å; E311-L313 HydrophobicContact CG-CD2 3.64Å; E311-L313 HydrophobicContact CG-CG 4.18Å; L313-L321 CarbonylContact C-O 3.03Å; L313-L321 VanDerWaalsContact CA-O 3.29Å; L313-L321 WeakPolarHBondContact CA-O 3.27Å
314I97.4Very high95.7Very high0 Ų020.3 Ų20.30%010%0.101CC..EExtended strand (participates in β ladder)trans-125.2126.5168-61.1-64.4000107.4F276 L277 V278 V316 L321 M477 L481 L484F276-I314 HydrophobicContact CD2-CD1 3.99Å; F276-I314 HydrophobicContact CD2-CG2 4.14Å; F276-I314 HydrophobicContact CE2-CD1 3.87Å; L277-I314 WeakPolarHBondContact O-CA 3.43Å; V278-I314 HydrophobicContact CB-CD1 3.87Å; V278-I314 HydrophobicContact CG2-CD1 3.72Å; I314-V316 HydrophobicContact CG2-CG2 4.49Å; I314-L321 HydrophobicContact CB-CB 4.44Å; I314-L321 PolarHBondContact N-O 2.85Å; I314-L321 PolarHBondContact O-N 2.96Å; I314-M477 HydrophobicContact CD1-CG 3.69Å; I314-M477 HydrophobicContact CD1-SD 3.74Å; I314-M477 HydrophobicContact CG1-CG 4.07Å; I314-L481 HydrophobicContact CG2-CD2 3.88Å; I314-L484 HydrophobicContact CG2-CD1 4.35Å
315H96Very high95.8Very high42 Ų4220.3 Ų20.319%0.19410%0.1CC..EExtended strand (participates in β ladder)trans-130.1130-177173.370.1000111.5P78 F276 L277 H317 H319 T320P78-H315 HydrophobicContact CG-CB 3.74Å; F276-H315 WeakPolarHBondContact CA-O 3.45Å; L277-H315 HydrophobicContact CB-CB 4.25Å; L277-H315 HydrophobicContact CD2-CB 4.22Å; L277-H315 PolarHBondContact N-O 2.97Å; L277-H315 PolarHBondContact O-N 3.08Å; H315-H317 PolarHBondContact CE1-O 2.74Å; H315-H317 PolarHBondContact NE2-O 3.32Å; H315-H319 WeakPolarHBondContact CA-O 3.31Å; H315-H319 PolarHBondContact ND1-O 3.37Å; H315-T320 PolarHBondContact ND1-OG1 2.69Å; H315-T320 VanDerWaalsContact ND1-OG1 3.11Å
316V94.1Very high96Very high7 Ų720.2 Ų20.24%0.04210%0.1CC..EExtended strand (participates in β ladder)trans-145.9117.2-172.71720000108.3F276 I314 N318 H319 L484 V486F276-V316 HydrophobicContact CB-CG2 3.45Å; F276-V316 VanDerWaalsContact CB-CG2 3.45Å; I314-V316 HydrophobicContact CG2-CG2 4.49Å; V316-N318 PolarHBondContact O-N 2.91Å; V316-N318 VanDerWaalsContact O-N 3.14Å; V316-H319 PolarHBondContact N-O 3.43Å; V316-H319 WeakPolarHBondContact O-CB 3.33Å; V316-H319 PolarHBondContact O-N 2.9Å; V316-L484 HydrophobicContact CB-CD1 4.12Å; V316-L484 HydrophobicContact CG2-CD1 3.9Å; V316-V486 HydrophobicContact CG1-CG2 3.77Å; V316-V486 HydrophobicContact CG2-CG2 4.05Å
317H88.1Confident96.2Very high160 Ų16019.7 Ų19.774%0.74110%0.097SC*.THydrogen-bonded Turntrans48.6-117.4-172.8-56.997000110.7H315H315-H317 PolarHBondContact CE1-O 2.74Å; H315-H317 PolarHBondContact NE2-O 3.32Å
318N90.6Very high96.1Very high88 Ų8820 Ų2047%0.47110%0.102SC..THydrogen-bonded Turntrans-973.5-178.1-61.5-1.4000112.8V316 D442 E443V316-N318 PolarHBondContact O-N 2.91Å; V316-N318 VanDerWaalsContact O-N 3.14Å; N318-D442 WeakPolarHBondContact O-CA 3.46Å; N318-E443 HydrophobicContact CB-CG 4.1Å; N318-E443 PolarHBondContact ND2-OE1 2.96Å; N318-E443 PolarHBondContact ND2-OE2 2.69Å
319H95.1Very high95.9Very high59 Ų5920.3 Ų20.327%0.27310%0.104SC..EExtended strand (participates in β ladder)trans-95.4132.5178.9-62.8-55.5000111.9H315 V316 L321 W440 V441 D442 L484H315-H319 WeakPolarHBondContact CA-O 3.31Å; H315-H319 PolarHBondContact ND1-O 3.37Å; V316-H319 PolarHBondContact N-O 3.43Å; V316-H319 WeakPolarHBondContact O-CB 3.33Å; V316-H319 PolarHBondContact O-N 2.9Å; H319-L321 HydrophobicContact CB-CD1 3.93Å; H319-W440 AromaticContact CG-NE1 3.5Å; H319-W440 AromaticContact ND1-NE1 3.36Å; H319-W440 PolarHBondContact ND1-NE1 2.79Å; H319-V441 WeakPolarHBondContact CA-O 3.37Å; H319-D442 IonicContact CE1-OD2 2.84Å; H319-D442 WeakPolarHBondContact ND1-CB 3.47Å; H319-L484 HydrophobicContact CB-CD2 3.97Å
320T96.8Very high95.7Very high23 Ų2320.3 Ų20.314%0.14110%0.104CC..EExtended strand (participates in β ladder)trans-124.6121172.9-560000109.7P78 V188 H315 V441P78-T320 HydrophobicContact CG-CG2 4.41Å; V188-T320 HydrophobicContact CG1-CG2 4.4Å; V188-T320 HydrophobicContact CG2-CG2 4.34Å; H315-T320 PolarHBondContact ND1-OG1 2.69Å; H315-T320 VanDerWaalsContact ND1-OG1 3.11Å; T320-V441 PolarHBondContact N-O 2.81Å; T320-V441 PolarHBondContact O-N 2.75Å
321L97.8Very high95.5Very high0 Ų020.2 Ų20.20%010%0.104CC..EExtended strand (participates in β ladder)trans-113.9137.2-177.3-69.170000108.9L313 I314 H319 C439 W440 Q480 L484L313-L321 CarbonylContact C-O 3.03Å; L313-L321 VanDerWaalsContact CA-O 3.29Å; L313-L321 WeakPolarHBondContact CA-O 3.27Å; I314-L321 HydrophobicContact CB-CB 4.44Å; I314-L321 PolarHBondContact N-O 2.85Å; I314-L321 PolarHBondContact O-N 2.96Å; H319-L321 HydrophobicContact CB-CD1 3.93Å; L321-C439 CarbonylContact C-O 3.59Å; L321-C439 VanDerWaalsContact CA-O 3.26Å; L321-C439 WeakPolarHBondContact CA-O 3.29Å; L321-W440 HydrophobicContact CD1-CD2 4.43Å; L321-W440 HydrophobicContact CD1-CG 3.97Å; L321-W440 HydrophobicContact CD2-CD2 4.31Å; L321-W440 HydrophobicContact CD2-CG 4.26Å; L321-W440 HydrophobicContact CG-CB 4.1Å; L321-W440 HydrophobicContact CG-CD2 4.28Å; L321-W440 HydrophobicContact CG-CG 3.75Å; L321-Q480 HydrophobicContact CD2-CB 3.82Å; L321-Q480 HydrophobicContact CD2-CG 3.81Å; L321-L484 HydrophobicContact CD1-CD1 3.89Å; L321-L484 HydrophobicContact CD1-CD2 4.17Å; L321-L484 HydrophobicContact CD1-CG 4.42Å; L321-L484 HydrophobicContact CD2-CD1 3.89Å; L321-L484 HydrophobicContact CD2-CG 4.24Å
322S97.7Very high95.3Very high0 Ų020.3 Ų20.30%011%0.105CC..EExtended strand (participates in β ladder)trans-131.1125.9-174.3141.80000110.5E311 Q312 C439E311-S322 PolarHBondContact OE1-OG 2.99Å; Q312-S322 WeakPolarHBondContact O-CA 3.47Å; S322-C439 PolarHBondContact N-O 3.05Å; S322-C439 PolarHBondContact O-N 3.05Å
323F98.3Very high95.1Very high1 Ų121.1 Ų21.10%0.00411%0.108CC..EExtended strand (participates in β ladder)trans-120.7121.5171178.8-121000111E311 Q312 Q325 W438 F454 I472 A473 V476E311-F323 WeakPolarHBondContact CA-O 3.37Å; Q312-F323 PolarHBondContact N-O 2.83Å; Q312-F323 PolarHBondContact O-N 2.9Å; F323-Q325 HydrophobicContact CD1-CG 4.32Å; F323-Q325 HydrophobicContact CE1-CG 3.58Å; F323-Q325 HydrophobicContact CZ-CG 3.76Å; F323-W438 HydrophobicContact CB-CB 4.44Å; F323-F454 HydrophobicContact CZ-CD2 4.08Å; F323-F454 HydrophobicContact CZ-CE2 4.45Å; F323-I472 HydrophobicContact CE1-CG2 3.95Å; F323-I472 HydrophobicContact CZ-CG2 3.81Å; F323-A473 HydrophobicContact CD1-CB 4.41Å; F323-A473 HydrophobicContact CE1-CB 4.45Å; F323-V476 HydrophobicContact CB-CG1 3.9Å; F323-V476 HydrophobicContact CD1-CB 3.99Å; F323-V476 HydrophobicContact CD1-CG1 4.08Å; F323-V476 HydrophobicContact CD1-CG2 4.07Å; F323-V476 HydrophobicContact CD2-CB 4.48Å; F323-V476 HydrophobicContact CD2-CG1 4Å; F323-V476 HydrophobicContact CD2-CG2 4.16Å; F323-V476 HydrophobicContact CE1-CB 4.19Å; F323-V476 HydrophobicContact CE1-CG2 3.8Å; F323-V476 HydrophobicContact CE2-CG2 3.92Å; F323-V476 HydrophobicContact CG-CB 4.15Å; F323-V476 HydrophobicContact CG-CG1 3.73Å; F323-V476 HydrophobicContact CG-CG2 4.24Å; F323-V476 HydrophobicContact CZ-CG2 3.73Å
324V98.2Very high94.9Very high6 Ų621.2 Ų21.24%0.03611%0.108CC..EExtended strand (participates in β ladder)trans-108.3135-175.8-179.60000111E309 E311 Y369 Q450 I453E309-V324 HydrophobicContact CG-CG1 3.47Å; E309-V324 VanDerWaalsContact CG-CG1 3.47Å; E311-V324 HydrophobicContact CB-CG2 4.25Å; E311-V324 HydrophobicContact CG-CG2 4.21Å; V324-Y369 HydrophobicContact CG1-CE1 4.34Å; V324-Q450 PolarHBondContact O-NE2 2.82Å; V324-I453 HydrophobicContact CB-CG2 4.47Å; V324-I453 HydrophobicContact CG1-CG2 4.47Å
325Q97.8Very high94.4Very high2 Ų222.2 Ų22.21%0.00912%0.115CC..EExtended strand (participates in β ladder)trans-130.7159.7170.7-65.3-178.676.800110T310 F323 F454 Q469T310-Q325 PolarHBondContact N-O 3.01Å; T310-Q325 PolarHBondContact O-N 3.33Å; F323-Q325 HydrophobicContact CD1-CG 4.32Å; F323-Q325 HydrophobicContact CE1-CG 3.58Å; F323-Q325 HydrophobicContact CZ-CG 3.76Å; Q325-F454 HydrophobicContact CG-CB 4.48Å; Q325-Q469 HydrophobicContact CB-CG 4.45Å; Q325-Q469 PolarHBondContact NE2-O 2.88Å
326T97Very high93.8Very high0 Ų020.4 Ų20.40%011%0.107CC..EExtended strand (participates in β ladder)trans-128.4161176.863.70000112.2Y307 V308 E309 I453 F454 R455 V456 Q469Y307-T326 HydrophobicContact CE1-CG2 4.45Å; Y307-T326 HydrophobicContact CE2-CG2 4.4Å; Y307-T326 VanDerWaalsContact OH-CG2 3.31Å; Y307-T326 WeakPolarHBondContact OH-CG2 3.19Å; V308-T326 WeakPolarHBondContact O-CA 3.48Å; E309-T326 HydrophobicContact CG-CG2 4.41Å; T326-I453 HydrophobicContact CG2-CD1 3.43Å; T326-I453 VanDerWaalsContact CG2-CD1 3.43Å; T326-F454 PolarHBondContact N-O 3.33Å; T326-R455 WeakPolarHBondContact O-CA 3.43Å; T326-R455 WeakPolarHBondContact OG1-CB 3.49Å; T326-R455 WeakPolarHBondContact OG1-CG 3.36Å; T326-V456 PolarHBondContact O-N 2.96Å; T326-Q469 VanDerWaalsContact C-NE2 3.32Å; T326-Q469 PolarHBondContact O-NE2 2.92Å
327R94.5Very high92.8Very high5 Ų523.8 Ų23.82%0.01913%0.127CC..EExtended strand (participates in β ladder)trans-151.6153.1173.554.8-171.6160.2-173.7-3.6108.9S282 Y307 V308 T310 V456 N466 Q469 N508S282-R327 PolarHBondContact OG-NH2 3.23Å; Y307-R327 CarbonylContact C-O 3.49Å; Y307-R327 WeakPolarHBondContact CA-O 3.3Å; V308-R327 HydrophobicContact CB-CG 3.85Å; V308-R327 HydrophobicContact CG1-CG 4.49Å; V308-R327 PolarHBondContact N-O 2.83Å; V308-R327 PolarHBondContact O-N 2.82Å; T310-R327 PolarHBondContact OG1-NE 2.91Å; T310-R327 PolarHBondContact OG1-NH2 2.92Å; T310-R327 VanDerWaalsContact OG1-NH2 3.15Å; R327-V456 WeakPolarHBondContact CB-O 3.43Å; R327-N466 PolarHBondContact NH1-OD1 2.91Å; R327-Q469 VanDerWaalsContact CD-OE1 3.31Å; R327-N508 PolarHBondContact NH2-ND2 3.04Å; R327-N508 PolarHBondContact NH2-OD1 3.15Å; R327-N508 VanDerWaalsContact NH2-OD1 3.12Å
328G91.9Very high91.6Very high14 Ų1418.4 Ų18.414%0.14412%0.116CC..EExtended strand (participates in β ladder)trans179.9-176.7178.600000112.1
329S92.4Very high90.2Very high11 Ų1121.1 Ų21.18%0.07712%0.12CC..  trans-65.6155.3172-149.70000111.7G297 A305 W334G297-S329 PolarHBondContact N-OG 3.19Å; A305-S329 VanDerWaalsContact O-CB 3.27Å; A305-S329 WeakPolarHBondContact O-CB 3.37Å; A305-S329 PolarHBondContact O-N 2.76Å; S329-W334 PolarHBondContact OG-NE1 3.2Å
330V93.2Very high88.7Confident0 Ų027.1 Ų27.10%014%0.141CC..  trans-62.9128.4170.71740000108.8G297 V332 W334 I387 Y391G297-V330 WeakPolarHBondContact CA-O 3.41Å; V330-V332 HydrophobicContact CG1-CG1 4.23Å; V330-V332 HydrophobicContact CG1-CG2 4.06Å; V330-V332 PolarHBondContact O-N 3.18Å; V330-W334 PolarHBondContact O-NE1 3.11Å; V330-I387 HydrophobicContact CB-CG2 3.87Å; V330-I387 HydrophobicContact CG1-CG2 3.87Å; V330-I387 HydrophobicContact CG2-CG2 3.89Å; V330-Y391 HydrophobicContact CG1-CD1 3.98Å; V330-Y391 HydrophobicContact CG1-CD2 3.97Å; V330-Y391 HydrophobicContact CG1-CG 3.62Å; V330-Y391 HydrophobicContact CG2-CD1 4.18Å
331P94.3Very high87.1Confident0 Ų032.5 Ų32.50%016%0.159CC..SBendtrans-75.145.5-172.327-31.8000115.1V304 F358 H361 F362 Y391V304-P331 HydrophobicContact CG1-CB 3.55Å; P331-F358 HydrophobicContact CB-CD2 4.11Å; P331-F358 HydrophobicContact CG-CD2 3.82Å; P331-F358 HydrophobicContact CG-CE2 3.74Å; P331-H361 HydrophobicContact CB-CB 4.45Å; P331-F362 HydrophobicContact CB-CE2 4.41Å; P331-F362 HydrophobicContact CG-CD2 4.43Å; P331-F362 HydrophobicContact CG-CE2 3.48Å; P331-F362 VanDerWaalsContact CG-CE2 3.48Å; P331-F362 HydrophobicContact CG-CZ 4.05Å; P331-Y391 HydrophobicContact CG-CD2 4.38Å; P331-Y391 HydrophobicContact CG-CE2 3.78Å
332V94.6Very high85.8Confident3 Ų335 Ų352%0.01817%0.173CC..SBendtrans-116.5167.1171-54.20000110.3G297 V298 V330 W334 L347 T354 Q394G297-V332 CarbonylContact C-O 3.59Å; G297-V332 WeakPolarHBondContact CA-O 3.32Å; V298-V332 PolarHBondContact N-O 2.82Å; V330-V332 HydrophobicContact CG1-CG1 4.23Å; V330-V332 HydrophobicContact CG1-CG2 4.06Å; V330-V332 PolarHBondContact O-N 3.18Å; V332-W334 HydrophobicContact CG2-CB 4.18Å; V332-W334 HydrophobicContact CG2-CG 4.1Å; V332-W334 PolarHBondContact O-N 3.23Å; V332-L347 HydrophobicContact CG2-CD2 3.98Å; V332-T354 HydrophobicContact CB-CG2 3.88Å; V332-T354 HydrophobicContact CG1-CG2 3.98Å; V332-Q394 HydrophobicContact CG1-CG 4.12Å
333F93.7Very high84.8Confident20 Ų2035.2 Ų35.29%0.08817%0.174CC..  trans-81.6106.9171.1-70.7-85.4000109.6V298 D299 L347 D348 K349 T354 Y357V298-F333 HydrophobicContact CG1-CD1 4.35Å; V298-F333 HydrophobicContact CG1-CD2 3.87Å; V298-F333 HydrophobicContact CG1-CE1 4.06Å; V298-F333 HydrophobicContact CG1-CE2 3.54Å; V298-F333 HydrophobicContact CG1-CG 4.25Å; V298-F333 HydrophobicContact CG1-CZ 3.64Å; V298-F333 WeakPolarHBondContact O-CE1 3.27Å; D299-F333 WeakPolarHBondContact O-CZ 3.43Å; F333-L347 CarbonylContact O-C 3.56Å; F333-L347 WeakPolarHBondContact O-CA 3.23Å; F333-D348 HydrophobicContact CB-CB 4.43Å; F333-D348 PolarHBondContact O-N 3.36Å; F333-K349 HydrophobicContact CB-CB 3.94Å; F333-K349 HydrophobicContact CB-CD 4.23Å; F333-K349 HydrophobicContact CB-CG 3.77Å; F333-K349 HydrophobicContact CD1-CD 4.2Å; F333-K349 HydrophobicContact CD1-CG 4.4Å; F333-K349 HydrophobicContact CD2-CB 4.35Å; F333-K349 HydrophobicContact CD2-CD 3.6Å; F333-K349 HydrophobicContact CD2-CG 4.11Å; F333-K349 HydrophobicContact CE2-CD 4Å; F333-K349 VanDerWaalsContact CE2-NZ 3.26Å; F333-K349 HydrophobicContact CG-CB 4.3Å; F333-K349 HydrophobicContact CG-CD 3.72Å; F333-K349 HydrophobicContact CG-CG 3.82Å; F333-K349 HydrophobicContact CZ-CD 4.47Å; F333-T354 HydrophobicContact CD2-CG2 4.31Å; F333-Y357 AromaticContact CE2-CD2 3.47Å; F333-Y357 HydrophobicContact CE2-CD2 3.47Å; F333-Y357 VanDerWaalsContact CE2-CD2 3.47Å; F333-Y357 HydrophobicContact CE2-CE2 4.1Å; F333-Y357 AromaticContact CE2-CG 3.71Å; F333-Y357 HydrophobicContact CE2-CG 3.71Å; F333-Y357 HydrophobicContact CZ-CD1 4.16Å; F333-Y357 AromaticContact CZ-CD2 3.85Å; F333-Y357 HydrophobicContact CZ-CD2 3.85Å; F333-Y357 HydrophobicContact CZ-CE2 4.28Å; F333-Y357 AromaticContact CZ-CG 3.76Å; F333-Y357 HydrophobicContact CZ-CG 3.76Å
334W92.5Very high84Confident4 Ų443.9 Ų43.92%0.01521%0.206CC..EExtended strand (participates in β ladder)trans-151.1151.2-179.772.8-77.1000113.7R296 G297 S329 V330 V332 Q336 P345 R346 L347 D348 I387 M459R296-W334 HydrophobicContact CB-CD2 4.28Å; R296-W334 HydrophobicContact CB-CZ2 4.42Å; R296-W334 WeakPolarHBondContact CB-O 3.41Å; G297-W334 VanDerWaalsContact CA-CD1 3.42Å; S329-W334 PolarHBondContact OG-NE1 3.2Å; V330-W334 PolarHBondContact O-NE1 3.11Å; V332-W334 HydrophobicContact CG2-CB 4.18Å; V332-W334 HydrophobicContact CG2-CG 4.1Å; V332-W334 PolarHBondContact O-N 3.23Å; W334-Q336 HydrophobicContact CZ3-CG 4.2Å; W334-P345 HydrophobicContact CE3-CB 4.07Å; W334-P345 HydrophobicContact CZ3-CB 4.12Å; W334-R346 VanDerWaalsContact CA-O 3.24Å; W334-R346 WeakPolarHBondContact CA-O 3.49Å; W334-R346 VanDerWaalsContact CB-O 3.26Å; W334-R346 WeakPolarHBondContact CB-O 3.47Å; W334-L347 HydrophobicContact CB-CD2 4.21Å; W334-D348 WeakPolarHBondContact CA-OD2 3.09Å; W334-I387 HydrophobicContact CB-CD1 3.7Å; W334-I387 HydrophobicContact CD2-CD1 3.84Å; W334-I387 HydrophobicContact CD2-CG1 4.17Å; W334-I387 HydrophobicContact CD2-CG2 4.36Å; W334-I387 HydrophobicContact CE3-CD1 3.82Å; W334-I387 HydrophobicContact CE3-CG1 3.92Å; W334-I387 HydrophobicContact CG-CD1 3.83Å; W334-I387 HydrophobicContact CZ2-CG2 4.35Å; W334-I387 HydrophobicContact CZ3-CG1 4.19Å; W334-M459 HydrophobicContact CH2-CB 4.42Å; W334-M459 HydrophobicContact CH2-CG 3.3Å; W334-M459 HydrophobicContact CH2-SD 4.33Å; W334-M459 HydrophobicContact CZ2-CG 4.24Å; W334-M459 HydrophobicContact CZ3-CG 3.69Å; W334-M459 HydrophobicContact CZ3-SD 4.13Å
335S88.7Confident83.5Confident21 Ų2144.1 Ų44.115%0.14721%0.208CC..EExtended strand (participates in β ladder)trans-140169.2179.366.70000112.3P345 R346 D348S335-P345 WeakPolarHBondContact O-CA 3.41Å; S335-R346 PolarHBondContact N-O 3.29Å; S335-R346 PolarHBondContact O-N 2.61Å; S335-R346 PolarHBondContact OG-NE 3.48Å; S335-R346 PolarHBondContact OG-NH2 3.08Å; S335-D348 WeakPolarHBondContact CB-OD2 3.26Å; S335-D348 PolarHBondContact N-OD2 2.87Å; S335-D348 VanDerWaalsContact OG-CG 3.25Å; S335-D348 PolarHBondContact OG-OD1 2.84Å; S335-D348 PolarHBondContact OG-OD2 3.3Å; S335-D348 VanDerWaalsContact OG-OD2 3.09Å
336Q83Confident83.1Confident4 Ų450 Ų502%0.01923%0.231CC..  trans-137.375.3179.2-98.7-174.1-54.400108.3Y293 W334 P343 P345 D460Y293-Q336 HydrophobicContact CD1-CB 3.8Å; Y293-Q336 HydrophobicContact CE1-CB 4.24Å; W334-Q336 HydrophobicContact CZ3-CG 4.2Å; Q336-P343 HydrophobicContact CB-CB 4.47Å; Q336-P343 HydrophobicContact CB-CG 3.96Å; Q336-P343 HydrophobicContact CG-CG 4.43Å; Q336-P343 PolarHBondContact NE2-O 3.5Å; Q336-P345 HydrophobicContact CG-CB 3.99Å; Q336-D460 PolarHBondContact NE2-OD2 3.27Å; Q336-D460 PolarHBondContact OE1-OD2 3.28Å
337V71.9Confident82.9Confident78 Ų7853.3 Ų53.347%0.47325%0.248SC..  trans-90.8157.2-177.2-58.30000112.5P343V337-P343 VanDerWaalsContact O-CB 3.32Å; V337-P343 WeakPolarHBondContact O-CB 3.37Å
338G64.4Low82.6Confident48 Ų4856.5 Ų56.550%0.49527%0.265SS..SBendtrans109.2164.7170.700000114.9R340G338-R340 PolarHBondContact O-N 3.14Å
339Y61.5Low82.6Confident145 Ų14558.4 Ų58.457%0.56927%0.27SS*.SBendtrans-90.912.5-165.5-57.3-63.7000115.4R552Y339-R552 PolarHBondContact O-NH2 2.91Å
340R62.3Low82.5Confident185 Ų18560.5 Ų60.570%0.69828%0.284SS*.SBendtrans-75.8153.6174.2-62.4-173.9-177.3-169.11.9110G338 N342G338-R340 PolarHBondContact O-N 3.14Å; R340-N342 PolarHBondContact O-N 3Å
341Y62.9Low82.4Confident136 Ų13664.1 Ų64.153%0.53330%0.301SS..SBendtrans-56.6-37.3178.9172-96000113.1S544 Y548Y341-S544 WeakPolarHBondContact OH-CB 3.32Å; Y341-Y548 AromaticContact CD2-CD2 3.62Å; Y341-Y548 HydrophobicContact CD2-CD2 3.62Å; Y341-Y548 HydrophobicContact CD2-CE2 4.35Å; Y341-Y548 AromaticContact CD2-CG 3.82Å; Y341-Y548 HydrophobicContact CD2-CG 3.82Å; Y341-Y548 HydrophobicContact CE2-CD2 4.45Å; Y341-Y548 HydrophobicContact CE2-CG 4.33Å; Y341-Y548 HydrophobicContact CG-CD2 4.36Å
342N71.1Confident82.2Confident52 Ų5273.2 Ų73.228%0.27834%0.341SS..SBendtrans-131.495.1171.1-177.9-37.9000107.7R340 R383R340-N342 PolarHBondContact O-N 3Å; N342-R383 VanDerWaalsContact CG-NH1 3.34Å; N342-R383 PolarHBondContact ND2-NH2 3.35Å; N342-R383 VanDerWaalsContact ND2-NH2 3.17Å; N342-R383 PolarHBondContact OD1-NH1 3.03Å
343P76.1Confident82Confident4 Ų477.9 Ų77.93%0.02636%0.362CS..PPolyproline II helixtrans-64.9144.6178.226.6-34.4000111.2Y293 Q336 V337Y293-P343 HydrophobicContact CD1-CG 3.89Å; Y293-P343 HydrophobicContact CE1-CG 3.85Å; Q336-P343 HydrophobicContact CB-CB 4.47Å; Q336-P343 HydrophobicContact CB-CG 3.96Å; Q336-P343 HydrophobicContact CG-CG 4.43Å; Q336-P343 PolarHBondContact NE2-O 3.5Å; V337-P343 VanDerWaalsContact O-CB 3.32Å; V337-P343 WeakPolarHBondContact O-CB 3.37Å
344R81.4Confident82Confident183 Ų18377.2 Ų77.269%0.69136%0.359SS*.PPolyproline II helixtrans-67.7138.7174.9-71.5-172.6176.7-170.2-1.5109.3
345P88.9Confident82.1Confident12 Ų1279 Ų798%0.07837%0.371CS..PPolyproline II helixtrans-67151.5168.931.5-36.1000110.2W334 S335 Q336 R383 I386 I387 M459W334-P345 HydrophobicContact CE3-CB 4.07Å; W334-P345 HydrophobicContact CZ3-CB 4.12Å; S335-P345 WeakPolarHBondContact O-CA 3.41Å; Q336-P345 HydrophobicContact CG-CB 3.99Å; P345-R383 WeakPolarHBondContact CG-O 3.49Å; P345-I386 HydrophobicContact CB-CG2 4.32Å; P345-I386 HydrophobicContact CG-CG2 3.68Å; P345-I387 HydrophobicContact CB-CD1 4.07Å; P345-I387 HydrophobicContact CB-CG1 3.81Å; P345-I387 HydrophobicContact CG-CG1 4.25Å; P345-M459 HydrophobicContact CB-CE 4.23Å; P345-M459 HydrophobicContact CB-SD 3.96Å; P345-M459 HydrophobicContact CG-CE 3.92Å; P345-M459 HydrophobicContact CG-SD 3.74Å
346R88.9Confident82.5Confident126 Ų12681.3 Ų81.348%0.47539%0.391SS..EExtended strand (participates in β ladder)trans-139.1149.116967.8-178.7-168.2-174.21.8109.1W334 S335 D348W334-R346 VanDerWaalsContact CA-O 3.24Å; W334-R346 WeakPolarHBondContact CA-O 3.49Å; W334-R346 VanDerWaalsContact CB-O 3.26Å; W334-R346 WeakPolarHBondContact CB-O 3.47Å; S335-R346 PolarHBondContact N-O 3.29Å; S335-R346 PolarHBondContact O-N 2.61Å; S335-R346 PolarHBondContact OG-NE 3.48Å; S335-R346 PolarHBondContact OG-NH2 3.08Å; R346-D348 IonicContact CZ-OD1 3.98Å; R346-D348 IonicContact NE-OD1 2.67Å; R346-D348 PolarHBondContact NE-OD1 2.98Å; R346-D348 IonicContact NH2-OD1 3.38Å; R346-D348 PolarHBondContact NH2-OD1 2.63Å
347L92.2Very high83.1Confident69 Ų6984.3 Ų84.336%0.36140%0.403SS..EExtended strand (participates in β ladder)trans-76.2137.6164.3-56.8175.7000108V332 F333 W334 I386 I387 A390V332-L347 HydrophobicContact CG2-CD2 3.98Å; F333-L347 CarbonylContact O-C 3.56Å; F333-L347 WeakPolarHBondContact O-CA 3.23Å; W334-L347 HydrophobicContact CB-CD2 4.21Å; L347-I386 HydrophobicContact CG-CG1 4.43Å; L347-I387 HydrophobicContact CD2-CD1 3.74Å; L347-A390 HydrophobicContact CD1-CB 4.03Å; L347-A390 HydrophobicContact CD2-CB 3.9Å
348D89.7Confident84.2Confident72 Ų7280.7 Ų80.739%0.38538%0.38SS..SBendtrans-99.2-5.4179.9-60.3-52.1000112.6F333 W334 S335 R346F333-D348 HydrophobicContact CB-CB 4.43Å; F333-D348 PolarHBondContact O-N 3.36Å; W334-D348 WeakPolarHBondContact CA-OD2 3.09Å; S335-D348 WeakPolarHBondContact CB-OD2 3.26Å; S335-D348 PolarHBondContact N-OD2 2.87Å; S335-D348 VanDerWaalsContact OG-CG 3.25Å; S335-D348 PolarHBondContact OG-OD1 2.84Å; S335-D348 PolarHBondContact OG-OD2 3.3Å; S335-D348 VanDerWaalsContact OG-OD2 3.09Å; R346-D348 IonicContact CZ-OD1 3.98Å; R346-D348 IonicContact NE-OD1 2.67Å; R346-D348 PolarHBondContact NE-OD1 2.98Å; R346-D348 IonicContact NH2-OD1 3.38Å; R346-D348 PolarHBondContact NH2-OD1 2.63Å
349K91.1Very high85.7Confident54 Ų5479.5 Ų79.524%0.23536%0.364CS..SBendtrans-144168.9173.2-63.4-163.7-165.6168.70111.2F333 E353F333-K349 HydrophobicContact CB-CB 3.94Å; F333-K349 HydrophobicContact CB-CD 4.23Å; F333-K349 HydrophobicContact CB-CG 3.77Å; F333-K349 HydrophobicContact CD1-CD 4.2Å; F333-K349 HydrophobicContact CD1-CG 4.4Å; F333-K349 HydrophobicContact CD2-CB 4.35Å; F333-K349 HydrophobicContact CD2-CD 3.6Å; F333-K349 HydrophobicContact CD2-CG 4.11Å; F333-K349 HydrophobicContact CE2-CD 4Å; F333-K349 VanDerWaalsContact CE2-NZ 3.26Å; F333-K349 HydrophobicContact CG-CB 4.3Å; F333-K349 HydrophobicContact CG-CD 3.72Å; F333-K349 HydrophobicContact CG-CG 3.82Å; F333-K349 HydrophobicContact CZ-CD 4.47Å; K349-E353 HydrophobicContact CB-CB 4.13Å; K349-E353 HydrophobicContact CD-CB 3.82Å
350S90.9Very high87.3Confident54 Ų5474.6 Ų74.638%0.37835%0.354SS..  trans-71.1166.5170.971.10000113.7E353 T354S350-E353 VanDerWaalsContact CB-OE2 3.24Å; S350-E353 WeakPolarHBondContact CB-OE2 3.41Å; S350-E353 PolarHBondContact N-OE2 3.41Å; S350-E353 PolarHBondContact O-N 3.4Å; S350-E353 VanDerWaalsContact OG-CG 3.28Å; S350-E353 WeakPolarHBondContact OG-CG 3.33Å; S350-E353 PolarHBondContact OG-N 3.37Å; S350-E353 PolarHBondContact OG-OE2 3.41Å; S350-T354 PolarHBondContact O-N 3.17Å; S350-T354 PolarHBondContact O-OG1 3.01Å
351E89.4Confident89Confident76 Ų7666 Ų6636%0.35532%0.322SS..SBendtrans-60.1-44.9176-163.3168.4157.400111.6T354 V355 K393 Q394 L397E351-T354 WeakPolarHBondContact O-CB 3.4Å; E351-T354 PolarHBondContact O-N 2.95Å; E351-T354 VanDerWaalsContact O-N 3.14Å; E351-V355 WeakPolarHBondContact O-CG2 3.45Å; E351-V355 PolarHBondContact O-N 3.17Å; E351-K393 WeakPolarHBondContact OE1-CD 3.41Å; E351-K393 IonicContact OE1-NZ 3.98Å; E351-K393 IonicContact OE2-NZ 3.84Å; E351-K393 PolarHBondContact OE2-NZ 2.97Å; E351-Q394 VanDerWaalsContact CG-NE2 3.33Å; E351-Q394 PolarHBondContact O-NE2 2.71Å; E351-L397 HydrophobicContact CG-CD1 4.26Å
352K90.8Very high90.6Very high192 Ų19259.5 Ų59.584%0.83530%0.296SS*.Hα-helixtrans-63-43179.3-65.7-176.1178.5-1780112.7T354K352-T354 PolarHBondContact O-N 3.23Å
353E90.9Very high91.8Very high100 Ų10061.7 Ų61.747%0.46731%0.305SS..Hα-helixtrans-71-11.2177.1-66.8167.393.700113.9K349 S350 Y357K349-E353 HydrophobicContact CB-CB 4.13Å; K349-E353 HydrophobicContact CD-CB 3.82Å; S350-E353 VanDerWaalsContact CB-OE2 3.24Å; S350-E353 WeakPolarHBondContact CB-OE2 3.41Å; S350-E353 PolarHBondContact N-OE2 3.41Å; S350-E353 PolarHBondContact O-N 3.4Å; S350-E353 VanDerWaalsContact OG-CG 3.28Å; S350-E353 WeakPolarHBondContact OG-CG 3.33Å; S350-E353 PolarHBondContact OG-N 3.37Å; S350-E353 PolarHBondContact OG-OE2 3.41Å; E353-Y357 WeakPolarHBondContact O-CD2 3.22Å; E353-Y357 WeakPolarHBondContact O-CE2 3.49Å
354T93.7Very high92.7Very high6 Ų664.5 Ų64.54%0.03732%0.318CS..Hα-helixtrans-89.9-34.5-180-59.50000111.6V332 F333 S350 E351 K352 A356 Y357 F358 Q394V332-T354 HydrophobicContact CB-CG2 3.88Å; V332-T354 HydrophobicContact CG1-CG2 3.98Å; F333-T354 HydrophobicContact CD2-CG2 4.31Å; S350-T354 PolarHBondContact O-N 3.17Å; S350-T354 PolarHBondContact O-OG1 3.01Å; E351-T354 WeakPolarHBondContact O-CB 3.4Å; E351-T354 PolarHBondContact O-N 2.95Å; E351-T354 VanDerWaalsContact O-N 3.14Å; K352-T354 PolarHBondContact O-N 3.23Å; T354-A356 PolarHBondContact O-N 3.39Å; T354-Y357 PolarHBondContact O-N 3.41Å; T354-Y357 VanDerWaalsContact O-N 3.08Å; T354-F358 PolarHBondContact O-N 2.93Å; T354-Q394 HydrophobicContact CG2-CG 4.32Å
355V95.2Very high93.4Very high43 Ų4355.9 Ų55.926%0.26129%0.285SS..Hα-helixtrans-48.5-55.8-171.8-178.90000112.8E351 Y357 F358 C359 Q394 L397E351-V355 WeakPolarHBondContact O-CG2 3.45Å; E351-V355 PolarHBondContact O-N 3.17Å; V355-Y357 PolarHBondContact O-N 2.99Å; V355-Y357 VanDerWaalsContact O-N 3.15Å; V355-F358 WeakPolarHBondContact O-CA 3.46Å; V355-F358 WeakPolarHBondContact O-CB 3.31Å; V355-F358 PolarHBondContact O-N 2.77Å; V355-C359 PolarHBondContact O-N 3.35Å; V355-C359 PolarHBondContact O-SG 3.07Å; V355-Q394 VanDerWaalsContact CA-OE1 3.27Å; V355-L397 HydrophobicContact CG2-CD1 4.02Å
356A95.5Very high93.7Very high68 Ų6856.1 Ų56.156%0.56229%0.286SS*.Hα-helixtrans-57.2-36.4-175.600000113.7T354 A360T354-A356 PolarHBondContact O-N 3.39Å; A356-A360 WeakPolarHBondContact O-CB 3.24Å; A356-A360 PolarHBondContact O-N 3.14Å; A356-A360 VanDerWaalsContact O-N 3.11Å
357Y95.9Very high94Very high68 Ų6855.6 Ų55.627%0.26729%0.292SS..Hα-helixtrans-82.5-26.8-179.8-50.8-86.3000112.1K300 F333 E353 T354 V355 H361K300-Y357 VanDerWaalsContact CA-CE1 3.49Å; K300-Y357 HydrophobicContact CB-CE1 4.03Å; K300-Y357 HydrophobicContact CG-CE1 4.41Å; K300-Y357 VanDerWaalsContact O-CD1 3.32Å; K300-Y357 WeakPolarHBondContact O-CD1 3.43Å; K300-Y357 VanDerWaalsContact O-CE1 3.24Å; K300-Y357 WeakPolarHBondContact O-CE1 3.48Å; F333-Y357 AromaticContact CE2-CD2 3.47Å; F333-Y357 HydrophobicContact CE2-CD2 3.47Å; F333-Y357 VanDerWaalsContact CE2-CD2 3.47Å; F333-Y357 HydrophobicContact CE2-CE2 4.1Å; F333-Y357 AromaticContact CE2-CG 3.71Å; F333-Y357 HydrophobicContact CE2-CG 3.71Å; F333-Y357 HydrophobicContact CZ-CD1 4.16Å; F333-Y357 AromaticContact CZ-CD2 3.85Å; F333-Y357 HydrophobicContact CZ-CD2 3.85Å; F333-Y357 HydrophobicContact CZ-CE2 4.28Å; F333-Y357 AromaticContact CZ-CG 3.76Å; F333-Y357 HydrophobicContact CZ-CG 3.76Å; E353-Y357 WeakPolarHBondContact O-CD2 3.22Å; E353-Y357 WeakPolarHBondContact O-CE2 3.49Å; T354-Y357 PolarHBondContact O-N 3.41Å; T354-Y357 VanDerWaalsContact O-N 3.08Å; V355-Y357 PolarHBondContact O-N 2.99Å; V355-Y357 VanDerWaalsContact O-N 3.15Å; Y357-H361 WeakPolarHBondContact O-CB 3.28Å; Y357-H361 PolarHBondContact O-N 3.32Å; Y357-H361 VanDerWaalsContact O-N 3.17Å
358F96.3Very high94Very high1 Ų155.3 Ų55.30%0.00429%0.29CS..Hα-helixtrans-69.4-47170.3-177.6-82000111.2P331 T354 V355 H361 F362 Y391 Q394 V395 F398P331-F358 HydrophobicContact CB-CD2 4.11Å; P331-F358 HydrophobicContact CG-CD2 3.82Å; P331-F358 HydrophobicContact CG-CE2 3.74Å; T354-F358 PolarHBondContact O-N 2.93Å; V355-F358 WeakPolarHBondContact O-CA 3.46Å; V355-F358 WeakPolarHBondContact O-CB 3.31Å; V355-F358 PolarHBondContact O-N 2.77Å; F358-H361 WeakPolarHBondContact O-CB 3.48Å; F358-H361 PolarHBondContact O-N 3.41Å; F358-F362 AromaticContact CD1-CD2 3.85Å; F358-F362 HydrophobicContact CD1-CD2 3.85Å; F358-F362 HydrophobicContact CD1-CE2 4.32Å; F358-F362 HydrophobicContact CD2-CD2 4.33Å; F358-F362 HydrophobicContact CD2-CE2 4.1Å; F358-F362 AromaticContact CE1-CD2 3.46Å; F358-F362 HydrophobicContact CE1-CD2 3.46Å; F358-F362 VanDerWaalsContact CE1-CD2 3.46Å; F358-F362 AromaticContact CE1-CE2 3.72Å; F358-F362 HydrophobicContact CE1-CE2 3.72Å; F358-F362 HydrophobicContact CE1-CG 4.45Å; F358-F362 HydrophobicContact CE2-CD2 4.01Å; F358-F362 AromaticContact CE2-CE2 3.49Å; F358-F362 HydrophobicContact CE2-CE2 3.49Å; F358-F362 VanDerWaalsContact CE2-CE2 3.49Å; F358-F362 HydrophobicContact CG-CD2 4.26Å; F358-F362 HydrophobicContact CG-CE2 4.49Å; F358-F362 AromaticContact CZ-CD2 3.56Å; F358-F362 HydrophobicContact CZ-CD2 3.56Å; F358-F362 AromaticContact CZ-CE2 3.26Å; F358-F362 HydrophobicContact CZ-CE2 3.26Å; F358-F362 HydrophobicContact CZ-CZ 4.25Å; F358-F362 WeakPolarHBondContact O-CD2 3.07Å; F358-F362 PolarHBondContact O-N 3.28Å; F358-Y391 AromaticContact CE2-CD2 3.86Å; F358-Y391 HydrophobicContact CE2-CD2 3.86Å; F358-Y391 AromaticContact CE2-CE2 3.89Å; F358-Y391 HydrophobicContact CE2-CE2 3.89Å; F358-Y391 HydrophobicContact CZ-CD2 4.44Å; F358-Y391 HydrophobicContact CZ-CE2 4.3Å; F358-Q394 HydrophobicContact CD1-CB 4.08Å; F358-Q394 HydrophobicContact CD2-CB 3.4Å; F358-Q394 HydrophobicContact CD2-CG 4.14Å; F358-Q394 HydrophobicContact CE1-CB 4.07Å; F358-Q394 VanDerWaalsContact CE1-O 3.25Å; F358-Q394 WeakPolarHBondContact CE1-O 3.45Å; F358-Q394 HydrophobicContact CE2-CB 3.35Å; F358-Q394 HydrophobicContact CE2-CG 4.44Å; F358-Q394 HydrophobicContact CG-CB 3.77Å; F358-Q394 VanDerWaalsContact CZ-C 3.48Å; F358-Q394 HydrophobicContact CZ-CB 3.71Å; F358-V395 HydrophobicContact CZ-CB 4.46Å; F358-V395 HydrophobicContact CZ-CG2 3.79Å; F358-F398 HydrophobicContact CD1-CB 4.11Å; F358-F398 HydrophobicContact CD1-CG 4.44Å; F358-F398 HydrophobicContact CE1-CB 3.72Å; F358-F398 HydrophobicContact CE1-CD1 4.41Å; F358-F398 HydrophobicContact CE1-CG 4.14Å
359C95.2Very high94.3Very high23 Ų2352.7 Ų52.716%0.15528%0.275CS..Hα-helixtrans-58-55.1175.1-610000110.5V355 H361 F362 E363 F398V355-C359 PolarHBondContact O-N 3.35Å; V355-C359 PolarHBondContact O-SG 3.07Å; C359-H361 PolarHBondContact O-N 2.93Å; C359-H361 VanDerWaalsContact O-N 3.17Å; C359-F362 PolarHBondContact O-N 3.43Å; C359-E363 WeakPolarHBondContact CB-OE1 3.43Å; C359-E363 WeakPolarHBondContact O-CB 3.46Å; C359-E363 VanDerWaalsContact O-CG 3.28Å; C359-E363 WeakPolarHBondContact O-CG 3.47Å; C359-E363 PolarHBondContact O-N 3.36Å; C359-F398 HydrophobicContact CB-CD2 4.09Å; C359-F398 HydrophobicContact CB-CE2 4.06Å
360A96.1Very high94.3Very high43 Ų4356 Ų5636%0.35529%0.29SS..Hα-helixtrans-54.8-38.4177.900000112.9A356 E364A356-A360 WeakPolarHBondContact O-CB 3.24Å; A356-A360 PolarHBondContact O-N 3.14Å; A356-A360 VanDerWaalsContact O-N 3.11Å; A360-E364 PolarHBondContact O-N 3.13Å; A360-E364 VanDerWaalsContact O-N 3.16Å
361H96.6Very high94.5Very high3 Ų356.2 Ų56.21%0.01428%0.284CS..Hα-helixtrans-63.2-51173.7-17863.1000112.2G302 P331 Y357 F358 C359 E364 Q365 R455G302-H361 VanDerWaalsContact O-CB 3.3Å; G302-H361 WeakPolarHBondContact O-CB 3.3Å; G302-H361 PolarHBondContact O-ND1 3.41Å; P331-H361 HydrophobicContact CB-CB 4.45Å; Y357-H361 WeakPolarHBondContact O-CB 3.28Å; Y357-H361 PolarHBondContact O-N 3.32Å; Y357-H361 VanDerWaalsContact O-N 3.17Å; F358-H361 WeakPolarHBondContact O-CB 3.48Å; F358-H361 PolarHBondContact O-N 3.41Å; C359-H361 PolarHBondContact O-N 2.93Å; C359-H361 VanDerWaalsContact O-N 3.17Å; H361-E364 PolarHBondContact O-N 3.21Å; H361-Q365 VanDerWaalsContact O-CG 3.25Å; H361-Q365 WeakPolarHBondContact O-CG 3.25Å; H361-Q365 PolarHBondContact O-N 3.13Å; H361-Q365 VanDerWaalsContact O-N 3.13Å; H361-R455 PolarHBondContact NE2-NH1 3.22Å; H361-R455 PolarHBondContact NE2-NH2 2.96Å
362F96.6Very high94.8Very high0 Ų052.6 Ų52.60%027%0.267CS..Hα-helixtrans-74.3-27.8-177.8-82.4-77.4000113.8P331 F358 C359 Q365 L366 Q372 I374 Y391 F398 L403P331-F362 HydrophobicContact CB-CE2 4.41Å; P331-F362 HydrophobicContact CG-CD2 4.43Å; P331-F362 HydrophobicContact CG-CE2 3.48Å; P331-F362 VanDerWaalsContact CG-CE2 3.48Å; P331-F362 HydrophobicContact CG-CZ 4.05Å; F358-F362 AromaticContact CD1-CD2 3.85Å; F358-F362 HydrophobicContact CD1-CD2 3.85Å; F358-F362 HydrophobicContact CD1-CE2 4.32Å; F358-F362 HydrophobicContact CD2-CD2 4.33Å; F358-F362 HydrophobicContact CD2-CE2 4.1Å; F358-F362 AromaticContact CE1-CD2 3.46Å; F358-F362 HydrophobicContact CE1-CD2 3.46Å; F358-F362 VanDerWaalsContact CE1-CD2 3.46Å; F358-F362 AromaticContact CE1-CE2 3.72Å; F358-F362 HydrophobicContact CE1-CE2 3.72Å; F358-F362 HydrophobicContact CE1-CG 4.45Å; F358-F362 HydrophobicContact CE2-CD2 4.01Å; F358-F362 AromaticContact CE2-CE2 3.49Å; F358-F362 HydrophobicContact CE2-CE2 3.49Å; F358-F362 VanDerWaalsContact CE2-CE2 3.49Å; F358-F362 HydrophobicContact CG-CD2 4.26Å; F358-F362 HydrophobicContact CG-CE2 4.49Å; F358-F362 AromaticContact CZ-CD2 3.56Å; F358-F362 HydrophobicContact CZ-CD2 3.56Å; F358-F362 AromaticContact CZ-CE2 3.26Å; F358-F362 HydrophobicContact CZ-CE2 3.26Å; F358-F362 HydrophobicContact CZ-CZ 4.25Å; F358-F362 WeakPolarHBondContact O-CD2 3.07Å; F358-F362 PolarHBondContact O-N 3.28Å; C359-F362 PolarHBondContact O-N 3.43Å; F362-Q365 PolarHBondContact O-N 3.44Å; F362-L366 WeakPolarHBondContact O-CB 3.31Å; F362-L366 VanDerWaalsContact O-CG 3.24Å; F362-L366 WeakPolarHBondContact O-CG 3.44Å; F362-L366 PolarHBondContact O-N 3.39Å; F362-Q372 VanDerWaalsContact CE1-OE1 3.24Å; F362-I374 HydrophobicContact CE1-CD1 3.98Å; F362-I374 HydrophobicContact CE1-CG1 4.21Å; F362-I374 HydrophobicContact CZ-CD1 3.77Å; F362-I374 HydrophobicContact CZ-CG1 4.28Å; F362-Y391 HydrophobicContact CE2-CE2 4.19Å; F362-Y391 HydrophobicContact CZ-CE2 4.04Å; F362-F398 HydrophobicContact CB-CD1 4.23Å; F362-F398 HydrophobicContact CB-CE1 3.6Å; F362-F398 HydrophobicContact CB-CZ 3.77Å; F362-F398 HydrophobicContact CG-CE1 4.42Å; F362-L403 HydrophobicContact CD1-CD1 3.64Å; F362-L403 HydrophobicContact CD1-CD2 3.99Å; F362-L403 HydrophobicContact CE1-CD1 3.54Å; F362-L403 HydrophobicContact CE1-CD2 4.12Å; F362-L403 HydrophobicContact CG-CD2 4.25Å; F362-L403 HydrophobicContact CZ-CD1 4.48Å
363E95.8Very high95.1Very high99 Ų9943.5 Ų43.546%0.46323%0.227SC..Hα-helixtrans-62.8-45170.4-73159.8-16200110.9C359 Q365 L366 N367 F398C359-E363 WeakPolarHBondContact CB-OE1 3.43Å; C359-E363 WeakPolarHBondContact O-CB 3.46Å; C359-E363 VanDerWaalsContact O-CG 3.28Å; C359-E363 WeakPolarHBondContact O-CG 3.47Å; C359-E363 PolarHBondContact O-N 3.36Å; E363-Q365 PolarHBondContact O-N 3.29Å; E363-L366 PolarHBondContact O-N 2.8Å; E363-N367 VanDerWaalsContact O-CB 3.25Å; E363-N367 WeakPolarHBondContact O-CB 3.46Å; E363-N367 PolarHBondContact O-N 2.88Å; E363-N367 PolarHBondContact O-ND2 3.23Å; E363-F398 HydrophobicContact CG-CE2 4.21Å; E363-F398 HydrophobicContact CG-CZ 4.24Å
364E95.3Very high95.3Very high63 Ų6338.7 Ų38.729%0.29421%0.205SC..Hα-helixtrans-57.9-47.3171.6-170.3-127.6-165.500111.2R208 A360 H361 N367 I368R208-E364 WeakPolarHBondContact CD-OE1 3.42Å; R208-E364 IonicContact NH1-OE1 3.79Å; A360-E364 PolarHBondContact O-N 3.13Å; A360-E364 VanDerWaalsContact O-N 3.16Å; H361-E364 PolarHBondContact O-N 3.21Å; E364-N367 PolarHBondContact O-N 2.92Å; E364-I368 HydrophobicContact CG-CD1 3.92Å; E364-I368 VanDerWaalsContact O-CG1 3.29Å; E364-I368 WeakPolarHBondContact O-CG1 3.33Å; E364-I368 PolarHBondContact O-N 2.73Å; E364-I368 VanDerWaalsContact O-N 3.09Å
365Q95.6Very high95.4Very high1 Ų138.4 Ų38.41%0.00520%0.203CC..Hα-helixtrans-63.9-44.1180-64.5-66.4-72.600112.9Y307 H361 F362 E363 I368 Y369Y307-Q365 VanDerWaalsContact CE2-OE1 3.32Å; Y307-Q365 VanDerWaalsContact OH-CD 3.28Å; Y307-Q365 PolarHBondContact OH-NE2 3.03Å; Y307-Q365 PolarHBondContact OH-OE1 3.45Å; H361-Q365 VanDerWaalsContact O-CG 3.25Å; H361-Q365 WeakPolarHBondContact O-CG 3.25Å; H361-Q365 PolarHBondContact O-N 3.13Å; H361-Q365 VanDerWaalsContact O-N 3.13Å; F362-Q365 PolarHBondContact O-N 3.44Å; E363-Q365 PolarHBondContact O-N 3.29Å; Q365-I368 PolarHBondContact O-N 3.12Å; Q365-Y369 WeakPolarHBondContact O-CB 3.43Å; Q365-Y369 VanDerWaalsContact O-CD2 3.23Å; Q365-Y369 WeakPolarHBondContact O-CD2 3.13Å; Q365-Y369 PolarHBondContact O-N 3.5Å
366L95.8Very high95.2Very high18 Ų1836.4 Ų36.49%0.09419%0.191CC..Hα-helixtrans-73.2-31.7179.6-65172.9000111.5F362 E363 I368 K370 Q372 F398 H402F362-L366 WeakPolarHBondContact O-CB 3.31Å; F362-L366 VanDerWaalsContact O-CG 3.24Å; F362-L366 WeakPolarHBondContact O-CG 3.44Å; F362-L366 PolarHBondContact O-N 3.39Å; E363-L366 PolarHBondContact O-N 2.8Å; L366-I368 PolarHBondContact O-N 2.7Å; L366-K370 WeakPolarHBondContact CD2-O 3.28Å; L366-K370 WeakPolarHBondContact O-CA 3.29Å; L366-K370 PolarHBondContact O-N 2.9Å; L366-Q372 HydrophobicContact CD2-CB 4.13Å; L366-F398 HydrophobicContact CD1-CE1 3.96Å; L366-F398 HydrophobicContact CD1-CZ 4.23Å; L366-H402 HydrophobicContact CD1-CB 4.38Å; L366-H402 HydrophobicContact CD2-CB 3.87Å
367N94.8Very high94.9Very high114 Ų11433.1 Ų33.161%0.6116%0.164SC*.Hα-helixtrans-61.5-44.6171.3-79.6-38.6000111.9E363 E364 K370E363-N367 VanDerWaalsContact O-CB 3.25Å; E363-N367 WeakPolarHBondContact O-CB 3.46Å; E363-N367 PolarHBondContact O-N 2.88Å; E363-N367 PolarHBondContact O-ND2 3.23Å; E364-N367 PolarHBondContact O-N 2.92Å; N367-K370 PolarHBondContact O-NZ 3.32Å
368I93.7Very high94.3Very high63 Ų6329.9 Ų29.932%0.32315%0.151SC..Hα-helixtrans-77.3-42.1-177.5-62.8170.4000112.3E364 Q365 L366E364-I368 HydrophobicContact CG-CD1 3.92Å; E364-I368 VanDerWaalsContact O-CG1 3.29Å; E364-I368 WeakPolarHBondContact O-CG1 3.33Å; E364-I368 PolarHBondContact O-N 2.73Å; E364-I368 VanDerWaalsContact O-N 3.09Å; Q365-I368 PolarHBondContact O-N 3.12Å; L366-I368 PolarHBondContact O-N 2.7Å
369Y94.6Very high93.5Very high18 Ų1831.3 Ų31.37%0.07116%0.159CC..Hα-helixtrans-115.60.7-169-52.8-77.3000115.4R208 Y307 E309 V324 Q365 K371 G452 I453R208-Y369 PolarHBondContact NH1-OH 2.91Å; R208-Y369 PolarHBondContact NH2-OH 3.02Å; Y307-Y369 VanDerWaalsContact OH-CE2 3.24Å; Y307-Y369 WeakPolarHBondContact OH-CE2 3.37Å; Y307-Y369 PolarHBondContact OH-OH 2.78Å; E309-Y369 VanDerWaalsContact OE2-CE1 3.27Å; E309-Y369 WeakPolarHBondContact OE2-CE1 3.43Å; E309-Y369 VanDerWaalsContact OE2-CZ 3.32Å; E309-Y369 PolarHBondContact OE2-OH 3.2Å; V324-Y369 HydrophobicContact CG1-CE1 4.34Å; Q365-Y369 WeakPolarHBondContact O-CB 3.43Å; Q365-Y369 VanDerWaalsContact O-CD2 3.23Å; Q365-Y369 WeakPolarHBondContact O-CD2 3.13Å; Q365-Y369 PolarHBondContact O-N 3.5Å; Y369-K371 VanDerWaalsContact C-N 3.26Å; Y369-K371 PolarHBondContact O-N 2.73Å; Y369-G452 WeakPolarHBondContact O-CA 3.05Å; Y369-I453 HydrophobicContact CD1-CD1 3.71Å; Y369-I453 HydrophobicContact CD1-CG1 4.26Å; Y369-I453 HydrophobicContact CD1-CG2 3.74Å; Y369-I453 HydrophobicContact CD2-CD1 3.5Å; Y369-I453 VanDerWaalsContact CD2-CD1 3.5Å; Y369-I453 HydrophobicContact CD2-CG1 4.33Å; Y369-I453 HydrophobicContact CE1-CD1 4.12Å; Y369-I453 HydrophobicContact CE2-CD1 3.96Å; Y369-I453 HydrophobicContact CG-CD1 3.39Å; Y369-I453 HydrophobicContact CG-CG1 3.86Å; Y369-I453 HydrophobicContact CG-CG2 4.13Å
370K91.7Very high92.7Very high123 Ų12333.1 Ų33.154%0.53517%0.165SC..SBendtrans64.5-59.8-179.8-51.6-48.9179.1-159.80115.9L366 N367 H402L366-K370 WeakPolarHBondContact CD2-O 3.28Å; L366-K370 WeakPolarHBondContact O-CA 3.29Å; L366-K370 PolarHBondContact O-N 2.9Å; N367-K370 PolarHBondContact O-NZ 3.32Å; K370-H402 WeakPolarHBondContact O-CB 3.4Å
371K95Very high91.5Very high59 Ų5935.6 Ų35.626%0.25719%0.186SC..EExtended strand (participates in β ladder)trans-123.6139.8178.2-172.8176.6-178.8-178.80110Y369 H402 D435 M436 E451 G452 I453Y369-K371 VanDerWaalsContact C-N 3.26Å; Y369-K371 PolarHBondContact O-N 2.73Å; K371-H402 WeakPolarHBondContact CA-O 3.41Å; K371-D435 IonicContact NZ-OD2 3.96Å; K371-D435 PolarHBondContact NZ-OD2 3.14Å; K371-M436 HydrophobicContact CD-CE 3.72Å; K371-M436 HydrophobicContact CG-CE 4.21Å; K371-E451 WeakPolarHBondContact CB-O 3.33Å; K371-E451 PolarHBondContact N-O 2.78Å; K371-G452 CarbonylContact O-C 3.58Å; K371-G452 WeakPolarHBondContact O-CA 3.45Å; K371-I453 PolarHBondContact O-N 3.21Å
372Q95.7Very high90.6Very high0 Ų037.2 Ų37.20%020%0.203CC..EExtended strand (participates in β ladder)trans-131.3127.2178.5-174.3160.2117.600111.6F362 L366 H402 L403 T404 I453 R455F362-Q372 VanDerWaalsContact CE1-OE1 3.24Å; L366-Q372 HydrophobicContact CD2-CB 4.13Å; Q372-H402 PolarHBondContact N-O 3.23Å; Q372-L403 HydrophobicContact CB-CD1 4.03Å; Q372-L403 HydrophobicContact CG-CD1 4.34Å; Q372-L403 WeakPolarHBondContact O-CA 3.38Å; Q372-T404 PolarHBondContact O-N 3.15Å; Q372-I453 WeakPolarHBondContact CA-O 3.23Å; Q372-I453 HydrophobicContact CG-CG1 4.32Å; Q372-R455 HydrophobicContact CG-CB 3.72Å; Q372-R455 VanDerWaalsContact OE1-CD 3.3Å
373V96.6Very high89.8Confident0 Ų042.7 Ų42.70%022%0.224CC..EExtended strand (participates in β ladder)trans-104.7108.2172.4-175.40000108.4I375 T404 V406 I432 M436 I453 F454 R455V373-I375 HydrophobicContact CG1-CG1 4.49Å; V373-I375 PolarHBondContact O-N 2.89Å; V373-T404 HydrophobicContact CG1-CG2 4.37Å; V373-V406 HydrophobicContact CG1-CG2 3.79Å; V373-I432 HydrophobicContact CG2-CG2 3.86Å; V373-M436 HydrophobicContact CG2-CE 3.66Å; V373-M436 HydrophobicContact CG2-SD 4.13Å; V373-I453 PolarHBondContact N-O 3.42Å; V373-F454 HydrophobicContact CB-CD1 3.7Å; V373-F454 HydrophobicContact CB-CE1 3.88Å; V373-F454 HydrophobicContact CG1-CD1 3.88Å; V373-F454 HydrophobicContact CG1-CE1 3.88Å; V373-F454 HydrophobicContact CG2-CD1 4.4Å; V373-F454 HydrophobicContact CG2-CE1 4.16Å; V373-F454 WeakPolarHBondContact O-CA 3.41Å; V373-R455 PolarHBondContact O-N 3.19Å
374I96.2Very high89.2Confident0 Ų038.7 Ų38.70%021%0.205CC..EExtended strand (participates in β ladder)trans-72.6124.2171.3-59.9163.4000108F362 N376 Y391 V395 L403 T404 Y405 V406 R455F362-I374 HydrophobicContact CE1-CD1 3.98Å; F362-I374 HydrophobicContact CE1-CG1 4.21Å; F362-I374 HydrophobicContact CZ-CD1 3.77Å; F362-I374 HydrophobicContact CZ-CG1 4.28Å; I374-N376 HydrophobicContact CG2-CB 4.35Å; I374-Y391 HydrophobicContact CD1-CE2 4.08Å; I374-Y391 WeakPolarHBondContact CD1-OH 3.18Å; I374-Y391 WeakPolarHBondContact CG1-OH 3.33Å; I374-Y391 HydrophobicContact CG2-CE1 3.5Å; I374-Y391 VanDerWaalsContact CG2-CE1 3.5Å; I374-Y391 VanDerWaalsContact CG2-OH 3.28Å; I374-Y391 WeakPolarHBondContact CG2-OH 3.23Å; I374-V395 HydrophobicContact CD1-CG2 3.69Å; I374-L403 HydrophobicContact CD1-CD1 3.78Å; I374-L403 HydrophobicContact CD1-CD2 4.11Å; I374-L403 HydrophobicContact CD1-CG 4.04Å; I374-L403 HydrophobicContact CG1-CD1 3.98Å; I374-T404 PolarHBondContact N-O 3.17Å; I374-Y405 HydrophobicContact CB-CD2 4.07Å; I374-Y405 HydrophobicContact CD1-CD2 4.08Å; I374-Y405 HydrophobicContact CG2-CD2 3.73Å; I374-Y405 HydrophobicContact CG2-CE2 4.08Å; I374-V406 PolarHBondContact O-N 3.06Å; I374-R455 WeakPolarHBondContact CA-O 3.17Å
375I94.5Very high88.9Confident0 Ų039.9 Ų39.90%021%0.209CC..EExtended strand (participates in β ladder)trans-109.6108.4165.1-59.7176.9000107.1V373 L377 V406 L425 I429 F454 R455 V456 N457 V468 I472V373-I375 HydrophobicContact CG1-CG1 4.49Å; V373-I375 PolarHBondContact O-N 2.89Å; I375-L377 HydrophobicContact CG2-CD2 3.75Å; I375-L377 HydrophobicContact CG2-CG 4.39Å; I375-V406 HydrophobicContact CG1-CB 4.4Å; I375-L425 HydrophobicContact CG2-CD2 4.07Å; I375-I429 HydrophobicContact CD1-CD1 3.69Å; I375-F454 HydrophobicContact CD1-CB 4.5Å; I375-F454 HydrophobicContact CD1-CD1 3.71Å; I375-F454 HydrophobicContact CD1-CE1 4.4Å; I375-F454 HydrophobicContact CD1-CG 4.41Å; I375-F454 HydrophobicContact CG1-CD1 4.26Å; I375-R455 PolarHBondContact N-O 3.34Å; I375-V456 HydrophobicContact CB-CG2 4.49Å; I375-N457 PolarHBondContact O-N 3.22Å; I375-V468 HydrophobicContact CD1-CG1 4.41Å; I375-V468 HydrophobicContact CG2-CG1 4.36Å; I375-I472 HydrophobicContact CD1-CD1 3.48Å; I375-I472 VanDerWaalsContact CD1-CD1 3.48Å
376N92.3Very high88.7Confident0 Ų043.5 Ų43.50%023%0.228CC..EExtended strand (participates in β ladder)trans-99107.4-177.2-164.624.6000111.2I374 V378 Y391 Y405 V406 F408I374-N376 HydrophobicContact CG2-CB 4.35Å; N376-V378 PolarHBondContact O-N 3.05Å; N376-V378 WeakPolarHBondContact OD1-CG2 3.44Å; N376-Y391 HydrophobicContact CB-CE1 4.49Å; N376-Y405 HydrophobicContact CB-CE2 3.88Å; N376-Y405 PolarHBondContact ND2-OH 3.19Å; N376-V406 PolarHBondContact N-O 3.36Å; N376-F408 PolarHBondContact O-N 3.35Å
377L89.2Confident88.5Confident0 Ų042.7 Ų42.70%022%0.224CC..  trans-90.326.7-178.1-51.9178.3000112.9I375 F408 F410 V456 N457 C458 R464 T465 V468I375-L377 HydrophobicContact CG2-CD2 3.75Å; I375-L377 HydrophobicContact CG2-CG 4.39Å; L377-F408 HydrophobicContact CD2-CB 4.34Å; L377-F408 HydrophobicContact CD2-CD1 3.88Å; L377-F410 HydrophobicContact CB-CB 4.44Å; L377-F410 HydrophobicContact CD2-CD2 4.46Å; L377-V456 HydrophobicContact CD1-CG1 3.61Å; L377-V456 HydrophobicContact CG-CG1 4.11Å; L377-N457 WeakPolarHBondContact CB-O 3.18Å; L377-N457 PolarHBondContact N-O 3.03Å; L377-C458 HydrophobicContact CB-CB 4.42Å; L377-R464 HydrophobicContact CD1-CB 4.07Å; L377-R464 PolarHBondContact O-NH1 2.82Å; L377-T465 HydrophobicContact CD1-CG2 4.48Å; L377-V468 HydrophobicContact CD1-CB 4.1Å; L377-V468 HydrophobicContact CD1-CG2 3.67Å; L377-V468 HydrophobicContact CD2-CG2 3.97Å; L377-V468 HydrophobicContact CG-CG2 4.48Å
378V83.1Confident88.3Confident0 Ų037.3 Ų37.30%020%0.196CC..  trans-81136.8-175.8157.60000110.6N376 Q380 E384 M459N376-V378 PolarHBondContact O-N 3.05Å; N376-V378 WeakPolarHBondContact OD1-CG2 3.44Å; V378-Q380 PolarHBondContact O-N 2.69Å; V378-Q380 PolarHBondContact O-NE2 2.72Å; V378-E384 HydrophobicContact CG1-CB 3.75Å; V378-M459 HydrophobicContact CG2-CB 4.17Å
379D79.6Confident88.2Confident30 Ų3037.3 Ų37.316%0.1620%0.196CC..  trans-58.9113.9171.6161.130.2000111.1A381 G382 R383 E384 K385 D409D379-A381 WeakPolarHBondContact OD1-CA 3.32Å; D379-A381 PolarHBondContact OD1-N 3.34Å; D379-G382 PolarHBondContact OD1-N 3.36Å; D379-G382 VanDerWaalsContact OD1-N 3.14Å; D379-G382 VanDerWaalsContact OD2-CA 3.23Å; D379-G382 WeakPolarHBondContact OD2-CA 3.46Å; D379-R383 PolarHBondContact OD2-N 2.69Å; D379-E384 HydrophobicContact CB-CB 3.92Å; D379-E384 HydrophobicContact CB-CG 3.86Å; D379-E384 PolarHBondContact N-OE2 3.27Å; D379-K385 PolarHBondContact O-N 2.83Å; D379-D409 WeakPolarHBondContact CA-OD2 3.33Å
380Q77.3Confident88.2Confident62 Ų6237 Ų3729%0.2920%0.198SC..SBendtrans-78.2-23.5179.8-54.1-61-76.600111.9V378 K385 S407 D409V378-Q380 PolarHBondContact O-N 2.69Å; V378-Q380 PolarHBondContact O-NE2 2.72Å; Q380-K385 VanDerWaalsContact O-CD 3.26Å; Q380-K385 WeakPolarHBondContact O-CD 3.49Å; Q380-K385 WeakPolarHBondContact O-CG 3.31Å; Q380-S407 PolarHBondContact NE2-OG 3.01Å; Q380-S407 PolarHBondContact OE1-OG 3.44Å; Q380-D409 HydrophobicContact CG-CB 4.16Å; Q380-D409 PolarHBondContact N-OD2 2.9Å
381A70.9Confident88.3Confident95 Ų9531.2 Ų31.279%0.78517%0.172SC*.SBendtrans-113.736.7-169.400000112.5D379D379-A381 WeakPolarHBondContact OD1-CA 3.32Å; D379-A381 PolarHBondContact OD1-N 3.34Å
382G78.1Confident88.2Confident37 Ų3730.8 Ų30.838%0.38117%0.172SC..SBendtrans-171.5-146.8-176.500000115.7D379 E384 K385D379-G382 PolarHBondContact OD1-N 3.36Å; D379-G382 VanDerWaalsContact OD1-N 3.14Å; D379-G382 VanDerWaalsContact OD2-CA 3.23Å; D379-G382 WeakPolarHBondContact OD2-CA 3.46Å; G382-E384 VanDerWaalsContact C-N 3.29Å; G382-E384 PolarHBondContact O-N 2.98Å; G382-K385 VanDerWaalsContact O-CB 3.27Å; G382-K385 WeakPolarHBondContact O-CB 3.46Å; G382-K385 PolarHBondContact O-N 2.98Å
383R79.6Confident88.2Confident114 Ų11435.4 Ų35.443%0.4319%0.193SC..THydrogen-bonded Turntrans-76.8-15.5-168.7-65.3-179.7-62.8119.78.8113.3N342 P345 D379N342-R383 VanDerWaalsContact CG-NH1 3.34Å; N342-R383 PolarHBondContact ND2-NH2 3.35Å; N342-R383 VanDerWaalsContact ND2-NH2 3.17Å; N342-R383 PolarHBondContact OD1-NH1 3.03Å; P345-R383 WeakPolarHBondContact CG-O 3.49Å; D379-R383 PolarHBondContact OD2-N 2.69Å
384E84.2Confident88.1Confident16 Ų1635.6 Ų35.68%0.07519%0.193CC..THydrogen-bonded Turntrans-82.4-18.5175.7-46-169.6153.800112.3V378 D379 G382 I386 I387 G388 M459 R464V378-E384 HydrophobicContact CG1-CB 3.75Å; D379-E384 HydrophobicContact CB-CB 3.92Å; D379-E384 HydrophobicContact CB-CG 3.86Å; D379-E384 PolarHBondContact N-OE2 3.27Å; G382-E384 VanDerWaalsContact C-N 3.29Å; G382-E384 PolarHBondContact O-N 2.98Å; E384-I386 VanDerWaalsContact C-N 3.31Å; E384-I386 PolarHBondContact O-N 3.43Å; E384-I387 PolarHBondContact O-N 2.9Å; E384-G388 PolarHBondContact O-N 3.28Å; E384-G388 VanDerWaalsContact O-N 3.17Å; E384-M459 VanDerWaalsContact CA-SD 3.6Å; E384-M459 HydrophobicContact CB-CB 4.08Å; E384-M459 HydrophobicContact CB-CE 4.45Å; E384-M459 HydrophobicContact CB-CG 4.49Å; E384-M459 HydrophobicContact CB-SD 3.69Å; E384-M459 HydrophobicContact CG-CB 4.04Å; E384-M459 HydrophobicContact CG-CE 3.9Å; E384-M459 HydrophobicContact CG-CG 4.49Å; E384-M459 HydrophobicContact CG-SD 3.77Å; E384-R464 IonicContact OE1-CZ 2.82Å; E384-R464 IonicContact OE1-NH1 2.68Å; E384-R464 IonicContact OE1-NH2 2.69Å; E384-R464 PolarHBondContact OE1-NH2 2.98Å; E384-R464 IonicContact OE2-CZ 3.55Å; E384-R464 IonicContact OE2-NH1 3.35Å; E384-R464 PolarHBondContact OE2-NH1 2.88Å; E384-R464 IonicContact OE2-NH2 2.83Å; E384-R464 PolarHBondContact OE2-NH2 3.15Å
385K87.6Confident88.1Confident87 Ų8735.6 Ų35.638%0.37819%0.194SC..Hα-helixtrans-52.2-40.8-176.2-165.3-168.5-168-56.40113.9D379 Q380 G382 I387 G388 D389D379-K385 PolarHBondContact O-N 2.83Å; Q380-K385 VanDerWaalsContact O-CD 3.26Å; Q380-K385 WeakPolarHBondContact O-CD 3.49Å; Q380-K385 WeakPolarHBondContact O-CG 3.31Å; G382-K385 VanDerWaalsContact O-CB 3.27Å; G382-K385 WeakPolarHBondContact O-CB 3.46Å; G382-K385 PolarHBondContact O-N 2.98Å; K385-I387 PolarHBondContact O-N 2.98Å; K385-I387 VanDerWaalsContact O-N 3.15Å; K385-G388 CarbonylContact O-C 3.57Å; K385-G388 WeakPolarHBondContact O-CA 3.47Å; K385-G388 PolarHBondContact O-N 2.93Å; K385-D389 IonicContact NZ-OD1 2.79Å; K385-D389 PolarHBondContact NZ-OD1 3.25Å; K385-D389 IonicContact NZ-OD2 2.71Å; K385-D389 PolarHBondContact NZ-OD2 2.88Å; K385-D389 WeakPolarHBondContact O-CB 3.39Å; K385-D389 VanDerWaalsContact O-CG 3.31Å; K385-D389 PolarHBondContact O-N 2.92Å
386I91.4Very high88.1Confident78 Ų7838.4 Ų38.440%0.421%0.208SC..Hα-helixtrans-57.3-30.9177.6-172.5173.5000113.2P345 L347 E384 A390P345-I386 HydrophobicContact CB-CG2 4.32Å; P345-I386 HydrophobicContact CG-CG2 3.68Å; L347-I386 HydrophobicContact CG-CG1 4.43Å; E384-I386 VanDerWaalsContact C-N 3.31Å; E384-I386 PolarHBondContact O-N 3.43Å; I386-A390 VanDerWaalsContact O-CB 3.31Å; I386-A390 WeakPolarHBondContact O-CB 3.25Å; I386-A390 PolarHBondContact O-N 3.01Å
387I91.7Very high88.1Confident0 Ų043 Ų430%023%0.233CC..Hα-helixtrans-86.1-32.3175.3-55-53.7000111V330 W334 P345 L347 E384 K385 Y391 M459V330-I387 HydrophobicContact CB-CG2 3.87Å; V330-I387 HydrophobicContact CG1-CG2 3.87Å; V330-I387 HydrophobicContact CG2-CG2 3.89Å; W334-I387 HydrophobicContact CB-CD1 3.7Å; W334-I387 HydrophobicContact CD2-CD1 3.84Å; W334-I387 HydrophobicContact CD2-CG1 4.17Å; W334-I387 HydrophobicContact CD2-CG2 4.36Å; W334-I387 HydrophobicContact CE3-CD1 3.82Å; W334-I387 HydrophobicContact CE3-CG1 3.92Å; W334-I387 HydrophobicContact CG-CD1 3.83Å; W334-I387 HydrophobicContact CZ2-CG2 4.35Å; W334-I387 HydrophobicContact CZ3-CG1 4.19Å; P345-I387 HydrophobicContact CB-CD1 4.07Å; P345-I387 HydrophobicContact CB-CG1 3.81Å; P345-I387 HydrophobicContact CG-CG1 4.25Å; L347-I387 HydrophobicContact CD2-CD1 3.74Å; E384-I387 PolarHBondContact O-N 2.9Å; K385-I387 PolarHBondContact O-N 2.98Å; K385-I387 VanDerWaalsContact O-N 3.15Å; I387-Y391 VanDerWaalsContact O-CB 3.31Å; I387-Y391 WeakPolarHBondContact O-CB 3.17Å; I387-Y391 PolarHBondContact O-N 2.86Å; I387-M459 HydrophobicContact CB-SD 4.4Å; I387-M459 HydrophobicContact CG1-CG 4.49Å; I387-M459 HydrophobicContact CG1-SD 3.95Å
388G91Very high88.4Confident2 Ų244.5 Ų44.52%0.02124%0.239CC..Hα-helixtrans-64-51.317300000113E384 K385 A390 Y391 L392E384-G388 PolarHBondContact O-N 3.28Å; E384-G388 VanDerWaalsContact O-N 3.17Å; K385-G388 CarbonylContact O-C 3.57Å; K385-G388 WeakPolarHBondContact O-CA 3.47Å; K385-G388 PolarHBondContact O-N 2.93Å; G388-A390 PolarHBondContact O-N 2.74Å; G388-Y391 WeakPolarHBondContact O-CB 3.24Å; G388-Y391 PolarHBondContact O-N 2.93Å; G388-Y391 VanDerWaalsContact O-N 3.14Å; G388-L392 PolarHBondContact O-N 3.37Å
389D92.2Very high88.9Confident62 Ų6247.2 Ų47.233%0.33225%0.253SS..Hα-helixtrans-58.2-48176.9-67.4-9.5000111K385 Y391 L392 K393K385-D389 IonicContact NZ-OD1 2.79Å; K385-D389 PolarHBondContact NZ-OD1 3.25Å; K385-D389 IonicContact NZ-OD2 2.71Å; K385-D389 PolarHBondContact NZ-OD2 2.88Å; K385-D389 WeakPolarHBondContact O-CB 3.39Å; K385-D389 VanDerWaalsContact O-CG 3.31Å; K385-D389 PolarHBondContact O-N 2.92Å; D389-Y391 VanDerWaalsContact C-N 3.27Å; D389-Y391 PolarHBondContact O-N 2.83Å; D389-L392 PolarHBondContact O-N 2.92Å; D389-K393 WeakPolarHBondContact O-CB 3.49Å; D389-K393 VanDerWaalsContact O-CG 3.27Å; D389-K393 WeakPolarHBondContact O-CG 3.46Å; D389-K393 PolarHBondContact O-N 2.9Å
390A93.8Very high89.5Confident13 Ų1347.8 Ų47.811%0.10726%0.257CS..Hα-helixtrans-62.4-34.5177.200000112.4L347 I386 G388 Q394L347-A390 HydrophobicContact CD1-CB 4.03Å; L347-A390 HydrophobicContact CD2-CB 3.9Å; I386-A390 VanDerWaalsContact O-CB 3.31Å; I386-A390 WeakPolarHBondContact O-CB 3.25Å; I386-A390 PolarHBondContact O-N 3.01Å; G388-A390 PolarHBondContact O-N 2.74Å; A390-Q394 WeakPolarHBondContact O-CG 3.48Å; A390-Q394 PolarHBondContact O-N 2.96Å
391Y94.3Very high90.2Very high0 Ų048.8 Ų48.80%027%0.271CS..Hα-helixtrans-69.9-50.4176.5-168.8-164000111.7V330 P331 F358 F362 I374 N376 I387 G388 D389 K393 Q394 V395 Y405 N457V330-Y391 HydrophobicContact CG1-CD1 3.98Å; V330-Y391 HydrophobicContact CG1-CD2 3.97Å; V330-Y391 HydrophobicContact CG1-CG 3.62Å; V330-Y391 HydrophobicContact CG2-CD1 4.18Å; P331-Y391 HydrophobicContact CG-CD2 4.38Å; P331-Y391 HydrophobicContact CG-CE2 3.78Å; F358-Y391 AromaticContact CE2-CD2 3.86Å; F358-Y391 HydrophobicContact CE2-CD2 3.86Å; F358-Y391 AromaticContact CE2-CE2 3.89Å; F358-Y391 HydrophobicContact CE2-CE2 3.89Å; F358-Y391 HydrophobicContact CZ-CD2 4.44Å; F358-Y391 HydrophobicContact CZ-CE2 4.3Å; F362-Y391 HydrophobicContact CE2-CE2 4.19Å; F362-Y391 HydrophobicContact CZ-CE2 4.04Å; I374-Y391 HydrophobicContact CD1-CE2 4.08Å; I374-Y391 WeakPolarHBondContact CD1-OH 3.18Å; I374-Y391 WeakPolarHBondContact CG1-OH 3.33Å; I374-Y391 HydrophobicContact CG2-CE1 3.5Å; I374-Y391 VanDerWaalsContact CG2-CE1 3.5Å; I374-Y391 VanDerWaalsContact CG2-OH 3.28Å; I374-Y391 WeakPolarHBondContact CG2-OH 3.23Å; N376-Y391 HydrophobicContact CB-CE1 4.49Å; I387-Y391 VanDerWaalsContact O-CB 3.31Å; I387-Y391 WeakPolarHBondContact O-CB 3.17Å; I387-Y391 PolarHBondContact O-N 2.86Å; G388-Y391 WeakPolarHBondContact O-CB 3.24Å; G388-Y391 PolarHBondContact O-N 2.93Å; G388-Y391 VanDerWaalsContact O-N 3.14Å; D389-Y391 VanDerWaalsContact C-N 3.27Å; D389-Y391 PolarHBondContact O-N 2.83Å; Y391-K393 VanDerWaalsContact C-N 3.33Å; Y391-K393 PolarHBondContact O-N 3.31Å; Y391-Q394 PolarHBondContact O-N 2.97Å; Y391-Q394 VanDerWaalsContact O-N 3.17Å; Y391-V395 HydrophobicContact CD2-CG2 4.18Å; Y391-V395 HydrophobicContact CE2-CG2 4.14Å; Y391-V395 WeakPolarHBondContact O-CG2 3.43Å; Y391-V395 PolarHBondContact O-N 3.21Å; Y391-Y405 AromaticContact CD1-CE2 3.9Å; Y391-Y405 HydrophobicContact CD1-CE2 3.9Å; Y391-Y405 HydrophobicContact CE1-CE2 4.12Å; Y391-Y405 HydrophobicContact CG-CE2 4.35Å; Y391-N457 HydrophobicContact CE1-CB 4.15Å; Y391-N457 WeakPolarHBondContact CE1-ND2 3.47Å; Y391-N457 PolarHBondContact OH-ND2 2.72Å
392L94Very high91.3Very high50 Ų5049 Ų4926%0.26226%0.255SS..Hα-helixtrans-59.1-43.6179.4175.158.2000111.5G388 D389 Q394 V395 L396 Y405 I894G388-L392 PolarHBondContact O-N 3.37Å; D389-L392 PolarHBondContact O-N 2.92Å; L392-Q394 PolarHBondContact O-N 2.91Å; L392-V395 PolarHBondContact O-N 3.05Å; L392-L396 HydrophobicContact CD1-CD1 4.24Å; L392-L396 HydrophobicContact CD1-CG 4.31Å; L392-L396 HydrophobicContact CG-CD1 4.07Å; L392-L396 WeakPolarHBondContact O-CG 3.42Å; L392-L396 PolarHBondContact O-N 3.39Å; L392-Y405 HydrophobicContact CB-CE1 4.47Å; L392-Y405 HydrophobicContact CD1-CD1 3.9Å; L392-Y405 HydrophobicContact CD1-CE1 3.84Å; L392-Y405 HydrophobicContact CD1-CG 4.44Å; L392-I894 HydrophobicContact CD1-CD1 4.26Å
393K94.1Very high92.1Very high97 Ų9747.3 Ų47.342%0.42224%0.237SC..Hα-helixtrans-56.6-45.7173.9-78.6173144-144.40113E351 D389 Y391 L396 L397E351-K393 WeakPolarHBondContact OE1-CD 3.41Å; E351-K393 IonicContact OE1-NZ 3.98Å; E351-K393 IonicContact OE2-NZ 3.84Å; E351-K393 PolarHBondContact OE2-NZ 2.97Å; D389-K393 WeakPolarHBondContact O-CB 3.49Å; D389-K393 VanDerWaalsContact O-CG 3.27Å; D389-K393 WeakPolarHBondContact O-CG 3.46Å; D389-K393 PolarHBondContact O-N 2.9Å; Y391-K393 VanDerWaalsContact C-N 3.33Å; Y391-K393 PolarHBondContact O-N 3.31Å; K393-L396 WeakPolarHBondContact O-CB 3.44Å; K393-L396 PolarHBondContact O-N 2.79Å; K393-L397 VanDerWaalsContact O-CG 3.32Å; K393-L397 WeakPolarHBondContact O-CG 3.31Å; K393-L397 PolarHBondContact O-N 3.11Å
394Q95.4Very high92.8Very high4 Ų442.8 Ų42.82%0.01922%0.222CC..Hα-helixtrans-70.3-32.8-179.8-64.1-80-5900112V332 E351 T354 V355 F358 A390 Y391 L392 L397 F398V332-Q394 HydrophobicContact CG1-CG 4.12Å; E351-Q394 VanDerWaalsContact CG-NE2 3.33Å; E351-Q394 PolarHBondContact O-NE2 2.71Å; T354-Q394 HydrophobicContact CG2-CG 4.32Å; V355-Q394 VanDerWaalsContact CA-OE1 3.27Å; F358-Q394 HydrophobicContact CD1-CB 4.08Å; F358-Q394 HydrophobicContact CD2-CB 3.4Å; F358-Q394 HydrophobicContact CD2-CG 4.14Å; F358-Q394 HydrophobicContact CE1-CB 4.07Å; F358-Q394 VanDerWaalsContact CE1-O 3.25Å; F358-Q394 WeakPolarHBondContact CE1-O 3.45Å; F358-Q394 HydrophobicContact CE2-CB 3.35Å; F358-Q394 HydrophobicContact CE2-CG 4.44Å; F358-Q394 HydrophobicContact CG-CB 3.77Å; F358-Q394 VanDerWaalsContact CZ-C 3.48Å; F358-Q394 HydrophobicContact CZ-CB 3.71Å; A390-Q394 WeakPolarHBondContact O-CG 3.48Å; A390-Q394 PolarHBondContact O-N 2.96Å; Y391-Q394 PolarHBondContact O-N 2.97Å; Y391-Q394 VanDerWaalsContact O-N 3.17Å; L392-Q394 PolarHBondContact O-N 2.91Å; Q394-L397 PolarHBondContact O-N 2.92Å; Q394-F398 WeakPolarHBondContact O-CB 3.28Å; Q394-F398 PolarHBondContact O-N 3.44Å
395V95.3Very high93.3Very high1 Ų142.2 Ų42.21%0.00622%0.219CC..Hα-helixtrans-61.7-48169.1174.20000110.9F358 I374 Y391 L392 L397 F398 N399 L403 Y405F358-V395 HydrophobicContact CZ-CB 4.46Å; F358-V395 HydrophobicContact CZ-CG2 3.79Å; I374-V395 HydrophobicContact CD1-CG2 3.69Å; Y391-V395 HydrophobicContact CD2-CG2 4.18Å; Y391-V395 HydrophobicContact CE2-CG2 4.14Å; Y391-V395 WeakPolarHBondContact O-CG2 3.43Å; Y391-V395 PolarHBondContact O-N 3.21Å; L392-V395 PolarHBondContact O-N 3.05Å; V395-L397 VanDerWaalsContact C-N 3.29Å; V395-L397 PolarHBondContact O-N 3.12Å; V395-F398 PolarHBondContact O-N 3.4Å; V395-N399 PolarHBondContact O-N 3.04Å; V395-L403 HydrophobicContact CG1-CD2 4.18Å; V395-L403 HydrophobicContact CG2-CD2 4.42Å; V395-Y405 HydrophobicContact CG2-CD2 4.05Å
396L94.4Very high93.5Very high58 Ų5838.1 Ų38.130%0.30420%0.202SC..Hα-helixtrans-60.1-35.8177-74.6165.5000112.8L392 K393 L889 I894L392-L396 HydrophobicContact CD1-CD1 4.24Å; L392-L396 HydrophobicContact CD1-CG 4.31Å; L392-L396 HydrophobicContact CG-CD1 4.07Å; L392-L396 WeakPolarHBondContact O-CG 3.42Å; L392-L396 PolarHBondContact O-N 3.39Å; K393-L396 WeakPolarHBondContact O-CB 3.44Å; K393-L396 PolarHBondContact O-N 2.79Å; L396-L889 HydrophobicContact CD2-CD1 3.75Å; L396-I894 HydrophobicContact CD2-CD1 3.57Å; L396-I894 HydrophobicContact CG-CD1 4.34Å
397L93.6Very high93.4Very high98 Ų9835.2 Ų35.251%0.51319%0.188SC..Hα-helixtrans-74.7-29.8176.1-70.8171.3000113.3E351 V355 K393 Q394 V395E351-L397 HydrophobicContact CG-CD1 4.26Å; V355-L397 HydrophobicContact CG2-CD1 4.02Å; K393-L397 VanDerWaalsContact O-CG 3.32Å; K393-L397 WeakPolarHBondContact O-CG 3.31Å; K393-L397 PolarHBondContact O-N 3.11Å; Q394-L397 PolarHBondContact O-N 2.92Å; V395-L397 VanDerWaalsContact C-N 3.29Å; V395-L397 PolarHBondContact O-N 3.12Å
398F94.6Very high93.1Very high30 Ų3035.3 Ų35.313%0.13219%0.189CC..Hα-helixtrans-80.4-29177.3-176.7-117.4000112.9F358 C359 F362 E363 L366 Q394 V395 N400 L403F358-F398 HydrophobicContact CD1-CB 4.11Å; F358-F398 HydrophobicContact CD1-CG 4.44Å; F358-F398 HydrophobicContact CE1-CB 3.72Å; F358-F398 HydrophobicContact CE1-CD1 4.41Å; F358-F398 HydrophobicContact CE1-CG 4.14Å; C359-F398 HydrophobicContact CB-CD2 4.09Å; C359-F398 HydrophobicContact CB-CE2 4.06Å; F362-F398 HydrophobicContact CB-CD1 4.23Å; F362-F398 HydrophobicContact CB-CE1 3.6Å; F362-F398 HydrophobicContact CB-CZ 3.77Å; F362-F398 HydrophobicContact CG-CE1 4.42Å; E363-F398 HydrophobicContact CG-CE2 4.21Å; E363-F398 HydrophobicContact CG-CZ 4.24Å; L366-F398 HydrophobicContact CD1-CE1 3.96Å; L366-F398 HydrophobicContact CD1-CZ 4.23Å; Q394-F398 WeakPolarHBondContact O-CB 3.28Å; Q394-F398 PolarHBondContact O-N 3.44Å; V395-F398 PolarHBondContact O-N 3.4Å; F398-N400 HydrophobicContact CD1-CB 3.63Å; F398-N400 HydrophobicContact CE1-CB 3.45Å; F398-N400 VanDerWaalsContact CE1-CB 3.45Å; F398-N400 HydrophobicContact CG-CB 4.47Å; F398-N400 HydrophobicContact CZ-CB 4.18Å; F398-N400 PolarHBondContact O-N 3.02Å; F398-L403 HydrophobicContact CD1-CD2 3.76Å; F398-L403 HydrophobicContact CE1-CD2 4.19Å
399N93.3Very high92.5Very high57 Ų5735.7 Ų35.731%0.30519%0.19SC..  trans41.654168.2-16539.8000115.6V395 S891V395-N399 PolarHBondContact O-N 3.04Å; N399-S891 WeakPolarHBondContact ND2-CB 3.44Å; N399-S891 PolarHBondContact ND2-OG 3.43Å; N399-S891 VanDerWaalsContact OD1-CB 3.31Å; N399-S891 WeakPolarHBondContact OD1-CB 3.46Å; N399-S891 PolarHBondContact OD1-OG 3.06Å
400N93.3Very high91.7Very high43 Ų4333 Ų3323%0.2318%0.175CC..  trans-108.8128.6-174-170-56.4000111.8F398 H402 L403 S891 C892F398-N400 HydrophobicContact CD1-CB 3.63Å; F398-N400 HydrophobicContact CE1-CB 3.45Å; F398-N400 VanDerWaalsContact CE1-CB 3.45Å; F398-N400 HydrophobicContact CG-CB 4.47Å; F398-N400 HydrophobicContact CZ-CB 4.18Å; F398-N400 PolarHBondContact O-N 3.02Å; N400-H402 PolarHBondContact O-N 2.85Å; N400-H402 WeakPolarHBondContact OD1-CB 3.49Å; N400-H402 PolarHBondContact OD1-N 3.44Å; N400-L403 HydrophobicContact CB-CB 4.3Å; N400-L403 WeakPolarHBondContact O-CB 3.45Å; N400-L403 PolarHBondContact O-N 3.05Å; N400-S891 CarbonylContact C-O 3.6Å; N400-C892 PolarHBondContact N-SG 2.96Å; N400-C892 VanDerWaalsContact N-SG 3.39Å; N400-C892 PolarHBondContact O-SG 3.15Å; N400-C892 VanDerWaalsContact O-SG 3.41Å
401S91.8Very high90.6Very high83 Ų8336.6 Ų36.658%0.5819%0.19SC*.THydrogen-bonded Turntrans-66.2-20.5-176.553.50000114.8L403 S891S401-L403 VanDerWaalsContact C-N 3.29Å; S401-S891 WeakPolarHBondContact CA-O 3.44Å; S401-S891 PolarHBondContact N-O 2.86Å; S401-S891 VanDerWaalsContact N-O 3.07Å
402H93.5Very high89.4Confident100 Ų10042.5 Ų42.546%0.46322%0.218SC..THydrogen-bonded Turntrans-87.30.5173.9-59.1-81.4000112.9L366 K370 K371 Q372 N400L366-H402 HydrophobicContact CD1-CB 4.38Å; L366-H402 HydrophobicContact CD2-CB 3.87Å; K370-H402 WeakPolarHBondContact O-CB 3.4Å; K371-H402 WeakPolarHBondContact CA-O 3.41Å; Q372-H402 PolarHBondContact N-O 3.23Å; N400-H402 PolarHBondContact O-N 2.85Å; N400-H402 WeakPolarHBondContact OD1-CB 3.49Å; N400-H402 PolarHBondContact OD1-N 3.44Å
403L94.6Very high88.1Confident0 Ų041.7 Ų41.70%021%0.212CC..EExtended strand (participates in β ladder)trans-110.7125.5175.5-166.763.8000110.8F362 Q372 I374 V395 F398 N400 S401F362-L403 HydrophobicContact CD1-CD1 3.64Å; F362-L403 HydrophobicContact CD1-CD2 3.99Å; F362-L403 HydrophobicContact CE1-CD1 3.54Å; F362-L403 HydrophobicContact CE1-CD2 4.12Å; F362-L403 HydrophobicContact CG-CD2 4.25Å; F362-L403 HydrophobicContact CZ-CD1 4.48Å; Q372-L403 HydrophobicContact CB-CD1 4.03Å; Q372-L403 HydrophobicContact CG-CD1 4.34Å; Q372-L403 WeakPolarHBondContact O-CA 3.38Å; I374-L403 HydrophobicContact CD1-CD1 3.78Å; I374-L403 HydrophobicContact CD1-CD2 4.11Å; I374-L403 HydrophobicContact CD1-CG 4.04Å; I374-L403 HydrophobicContact CG1-CD1 3.98Å; V395-L403 HydrophobicContact CG1-CD2 4.18Å; V395-L403 HydrophobicContact CG2-CD2 4.42Å; F398-L403 HydrophobicContact CD1-CD2 3.76Å; F398-L403 HydrophobicContact CE1-CD2 4.19Å; N400-L403 HydrophobicContact CB-CB 4.3Å; N400-L403 WeakPolarHBondContact O-CB 3.45Å; N400-L403 PolarHBondContact O-N 3.05Å; S401-L403 VanDerWaalsContact C-N 3.29Å
404T94Very high86.7Confident19 Ų1937.5 Ų37.512%0.11720%0.195CC..EExtended strand (participates in β ladder)trans-119.1140175.6-51.90000109.2Q372 V373 I374 G893 I895Q372-T404 PolarHBondContact O-N 3.15Å; V373-T404 HydrophobicContact CG1-CG2 4.37Å; I374-T404 PolarHBondContact N-O 3.17Å; T404-G893 CarbonylContact C-O 3.6Å; T404-G893 WeakPolarHBondContact CA-O 3.41Å; T404-G893 WeakPolarHBondContact CG2-O 3.35Å; T404-I895 HydrophobicContact CG2-CD1 4.46Å
405Y94.4Very high84.9Confident4 Ų447 Ų472%0.01623%0.231CC..EExtended strand (participates in β ladder)trans-120.7116.6179.5-179.7-86.2000111.4I374 N376 Y391 L392 V395 G893 I894 I895I374-Y405 HydrophobicContact CB-CD2 4.07Å; I374-Y405 HydrophobicContact CD1-CD2 4.08Å; I374-Y405 HydrophobicContact CG2-CD2 3.73Å; I374-Y405 HydrophobicContact CG2-CE2 4.08Å; N376-Y405 HydrophobicContact CB-CE2 3.88Å; N376-Y405 PolarHBondContact ND2-OH 3.19Å; Y391-Y405 AromaticContact CD1-CE2 3.9Å; Y391-Y405 HydrophobicContact CD1-CE2 3.9Å; Y391-Y405 HydrophobicContact CE1-CE2 4.12Å; Y391-Y405 HydrophobicContact CG-CE2 4.35Å; L392-Y405 HydrophobicContact CB-CE1 4.47Å; L392-Y405 HydrophobicContact CD1-CD1 3.9Å; L392-Y405 HydrophobicContact CD1-CE1 3.84Å; L392-Y405 HydrophobicContact CD1-CG 4.44Å; V395-Y405 HydrophobicContact CG2-CD2 4.05Å; Y405-G893 PolarHBondContact N-O 3.19Å; Y405-I894 WeakPolarHBondContact O-CA 3.34Å; Y405-I895 PolarHBondContact O-N 3.47Å
406V92.4Very high82.9Confident2 Ų250.4 Ų50.41%0.01227%0.266CS..EExtended strand (participates in β ladder)trans-108.1119.6176.5-170.60000108.6V373 I374 I375 N376 L425 I429 I895V373-V406 HydrophobicContact CG1-CG2 3.79Å; I374-V406 PolarHBondContact O-N 3.06Å; I375-V406 HydrophobicContact CG1-CB 4.4Å; N376-V406 PolarHBondContact N-O 3.36Å; V406-L425 HydrophobicContact CG1-CD1 4.2Å; V406-I429 HydrophobicContact CG1-CG2 4.4Å; V406-I895 WeakPolarHBondContact CA-O 3.5Å; V406-I895 HydrophobicContact CG1-CB 4.4Å; V406-I895 HydrophobicContact CG1-CG2 4.46Å; V406-I895 HydrophobicContact CG2-CB 4.31Å; V406-I895 HydrophobicContact CG2-CD1 4.43Å
407S89.5Confident80.9Confident16 Ų1651.5 Ų51.511%0.11227%0.271CS..EExtended strand (participates in β ladder)trans-96.8128.1172.1-154.50000109.8Q380 I895 S897Q380-S407 PolarHBondContact NE2-OG 3.01Å; Q380-S407 PolarHBondContact OE1-OG 3.44Å; S407-I895 PolarHBondContact N-O 2.92Å; S407-S897 PolarHBondContact O-N 3.16Å; S407-S897 PolarHBondContact O-OG 3.14Å
408F86.6Confident79.3Confident2 Ų252.9 Ų52.91%0.00927%0.273CS..  trans-140107178.3179.9-98.5000110.4N376 L377 F410 H413 L425 S897N376-F408 PolarHBondContact O-N 3.35Å; L377-F408 HydrophobicContact CD2-CB 4.34Å; L377-F408 HydrophobicContact CD2-CD1 3.88Å; F408-F410 HydrophobicContact CD1-CB 4.38Å; F408-F410 HydrophobicContact CD1-CD2 4.49Å; F408-F410 HydrophobicContact CE1-CB 4.42Å; F408-F410 HydrophobicContact CE1-CD2 4.13Å; F408-F410 PolarHBondContact O-N 3.03Å; F408-H413 HydrophobicContact CE1-CB 4.11Å; F408-H413 HydrophobicContact CE2-CB 3.95Å; F408-H413 AromaticContact CE2-CD2 3.64Å; F408-H413 AromaticContact CE2-CG 3.61Å; F408-H413 HydrophobicContact CZ-CB 3.5Å; F408-H413 AromaticContact CZ-CG 3.72Å; F408-L425 HydrophobicContact CB-CD1 4.17Å; F408-L425 HydrophobicContact CB-CD2 4.37Å; F408-L425 HydrophobicContact CD1-CD2 3.99Å; F408-L425 HydrophobicContact CD2-CB 4.01Å; F408-L425 HydrophobicContact CD2-CD1 3.99Å; F408-L425 HydrophobicContact CD2-CD2 4.36Å; F408-L425 HydrophobicContact CD2-CG 4.34Å; F408-L425 HydrophobicContact CE1-CD2 4.33Å; F408-L425 HydrophobicContact CE2-CB 3.81Å; F408-L425 HydrophobicContact CG-CB 4.46Å; F408-L425 HydrophobicContact CG-CD1 4.13Å; F408-L425 HydrophobicContact CG-CD2 3.99Å; F408-L425 HydrophobicContact CG-CG 4.42Å; F408-L425 HydrophobicContact CZ-CB 4.07Å; F408-S897 WeakPolarHBondContact CD2-OG 3.48Å
409D78.3Confident77.6Confident11 Ų1151.9 Ų51.96%0.05927%0.268CS..  trans-74.497.2177.9-162.9-55.5000110.9D379 Q380 H411 E412 H413D379-D409 WeakPolarHBondContact CA-OD2 3.33Å; Q380-D409 HydrophobicContact CG-CB 4.16Å; Q380-D409 PolarHBondContact N-OD2 2.9Å; D409-H411 VanDerWaalsContact C-N 3.26Å; D409-H411 PolarHBondContact O-N 3.16Å; D409-H411 WeakPolarHBondContact OD1-CA 3.11Å; D409-H411 WeakPolarHBondContact OD1-CB 3.37Å; D409-H411 PolarHBondContact OD1-N 2.99Å; D409-E412 HydrophobicContact CB-CB 4.14Å; D409-E412 PolarHBondContact O-N 3.44Å; D409-E412 PolarHBondContact OD1-N 2.89Å; D409-H413 WeakPolarHBondContact O-CB 3.39Å; D409-H413 PolarHBondContact O-N 3.03Å; D409-H413 PolarHBondContact O-ND1 2.91Å
410F73.6Confident76.1Confident4 Ų456.4 Ų56.42%0.01829%0.288CS..Hα-helixtrans-65.7-25.6179.9-166.6-77000113L377 F408 C414 F419 V422 R464 V468L377-F410 HydrophobicContact CB-CB 4.44Å; L377-F410 HydrophobicContact CD2-CD2 4.46Å; F408-F410 HydrophobicContact CD1-CB 4.38Å; F408-F410 HydrophobicContact CD1-CD2 4.49Å; F408-F410 HydrophobicContact CE1-CB 4.42Å; F408-F410 HydrophobicContact CE1-CD2 4.13Å; F408-F410 PolarHBondContact O-N 3.03Å; F410-C414 HydrophobicContact CD1-CB 4.07Å; F410-C414 HydrophobicContact CE1-CB 3.88Å; F410-C414 HydrophobicContact CZ-CB 4.36Å; F410-C414 VanDerWaalsContact O-CB 3.24Å; F410-C414 WeakPolarHBondContact O-CB 3.27Å; F410-C414 PolarHBondContact O-N 2.83Å; F410-F419 HydrophobicContact CE1-CD1 4.09Å; F410-F419 AromaticContact CE1-CE1 3.77Å; F410-F419 HydrophobicContact CE1-CE1 3.77Å; F410-F419 AromaticContact CZ-CD1 3.75Å; F410-F419 HydrophobicContact CZ-CD1 3.75Å; F410-F419 AromaticContact CZ-CE1 3.78Å; F410-F419 HydrophobicContact CZ-CE1 3.78Å; F410-V422 HydrophobicContact CE2-CG2 3.99Å; F410-R464 HydrophobicContact CB-CG 4.35Å; F410-R464 HydrophobicContact CD1-CG 3.5Å; F410-R464 HydrophobicContact CD2-CG 4.07Å; F410-R464 HydrophobicContact CE1-CG 3.69Å; F410-R464 HydrophobicContact CE2-CG 4.21Å; F410-R464 HydrophobicContact CG-CG 3.71Å; F410-R464 HydrophobicContact CZ-CG 4.04Å; F410-V468 HydrophobicContact CD2-CG2 4.38Å; F410-V468 HydrophobicContact CE2-CG2 4.18Å
411H71.1Confident75.1Confident90 Ų9056.9 Ų56.942%0.41729%0.29SS..Hα-helixtrans-79.2-34.6179.9-69.9112.2000112.3D409 R415 R464D409-H411 VanDerWaalsContact C-N 3.26Å; D409-H411 PolarHBondContact O-N 3.16Å; D409-H411 WeakPolarHBondContact OD1-CA 3.11Å; D409-H411 WeakPolarHBondContact OD1-CB 3.37Å; D409-H411 PolarHBondContact OD1-N 2.99Å; H411-R415 WeakPolarHBondContact O-CB 2.97Å; H411-R415 PolarHBondContact O-N 3.38Å; H411-R464 PolarHBondContact CE1-NH1 3.27Å; H411-R464 VanDerWaalsContact CE1-NH1 3.26Å
412E69.9Low74.4Confident124 Ų12453.3 Ų53.358%0.57926%0.264SS*.Hα-helixtrans-70.6-57.3169.7-177.5170.3-144.700110.9D409 C414 R415D409-E412 HydrophobicContact CB-CB 4.14Å; D409-E412 PolarHBondContact O-N 3.44Å; D409-E412 PolarHBondContact OD1-N 2.89Å; E412-C414 PolarHBondContact O-N 3.44Å; E412-R415 WeakPolarHBondContact O-CB 3.45Å; E412-R415 PolarHBondContact O-N 3.28Å; E412-R415 VanDerWaalsContact O-N 3.16Å
413H67.2Low73.7Confident32 Ų3253.3 Ų53.315%0.14827%0.265CS..Hα-helixtrans-65.6-41-172.9-70.876.5000112.5F408 D409 R415 N421F408-H413 HydrophobicContact CE1-CB 4.11Å; F408-H413 HydrophobicContact CE2-CB 3.95Å; F408-H413 AromaticContact CE2-CD2 3.64Å; F408-H413 AromaticContact CE2-CG 3.61Å; F408-H413 HydrophobicContact CZ-CB 3.5Å; F408-H413 AromaticContact CZ-CG 3.72Å; D409-H413 WeakPolarHBondContact O-CB 3.39Å; D409-H413 PolarHBondContact O-N 3.03Å; D409-H413 PolarHBondContact O-ND1 2.91Å; H413-R415 VanDerWaalsContact C-N 3.34Å; H413-N421 HydrophobicContact CB-CB 4.5Å; H413-N421 WeakPolarHBondContact O-CB 3.5Å; H413-N421 PolarHBondContact O-ND2 3.31Å
414C63.1Low73.3Confident9 Ų957 Ų576%0.06129%0.288CS..THydrogen-bonded Turntrans-94.521.4177.4-57.20000113.3F410 E412 M417 F419F410-C414 HydrophobicContact CD1-CB 4.07Å; F410-C414 HydrophobicContact CE1-CB 3.88Å; F410-C414 HydrophobicContact CZ-CB 4.36Å; F410-C414 VanDerWaalsContact O-CB 3.24Å; F410-C414 WeakPolarHBondContact O-CB 3.27Å; F410-C414 PolarHBondContact O-N 2.83Å; E412-C414 PolarHBondContact O-N 3.44Å; C414-M417 PolarHBondContact O-N 3.04Å; C414-M417 VanDerWaalsContact O-N 3.09Å; C414-F419 HydrophobicContact CB-CD1 4.05Å; C414-F419 HydrophobicContact CB-CE1 4.37Å
415R59.3Low73Confident204 Ų20456.4 Ų56.477%0.7728%0.283SS*.G310 helixtrans-58.1138.7176.9-166.7169.5178.7174.3-1.6110.3H411 E412 H413 M417H411-R415 WeakPolarHBondContact O-CB 2.97Å; H411-R415 PolarHBondContact O-N 3.38Å; E412-R415 WeakPolarHBondContact O-CB 3.45Å; E412-R415 PolarHBondContact O-N 3.28Å; E412-R415 VanDerWaalsContact O-N 3.16Å; H413-R415 VanDerWaalsContact C-N 3.34Å; R415-M417 VanDerWaalsContact C-N 3.27Å; R415-M417 PolarHBondContact O-N 3.04Å
416G52.3Low72.7Confident72 Ų7256.2 Ų56.274%0.74228%0.283SS*.G310 helixtrans71.416.4-174.600000114.9K418G416-K418 VanDerWaalsContact C-N 3.34Å
417M53.4Low72.5Confident82 Ų8260.3 Ų60.340%0.40431%0.305SS..G310 helixtrans70.621.7-177.5-48.5-66.4157.500114.6C414 R415 F419C414-M417 PolarHBondContact O-N 3.04Å; C414-M417 VanDerWaalsContact O-N 3.09Å; R415-M417 VanDerWaalsContact C-N 3.27Å; R415-M417 PolarHBondContact O-N 3.04Å; M417-F419 HydrophobicContact CB-CD2 4.27Å; M417-F419 HydrophobicContact CB-CE2 3.76Å; M417-F419 HydrophobicContact CG-CE2 4.39Å; M417-F419 WeakPolarHBondContact O-CD2 3.39Å; M417-F419 PolarHBondContact O-N 2.96Å; M417-F419 HydrophobicContact SD-CE2 3.91Å; M417-F419 HydrophobicContact SD-CZ 3.88Å
418K59.2Low72.5Confident127 Ų12762.9 Ų62.955%0.55233%0.327SS*.  trans-75.968.5173.5-65-169174.7-166.70112G416 E420 N421G416-K418 VanDerWaalsContact C-N 3.34Å; K418-E420 PolarHBondContact O-N 3.45Å; K418-N421 WeakPolarHBondContact O-CB 3.32Å; K418-N421 PolarHBondContact O-N 3.15Å
419F58.7Low72.7Confident8 Ų862.8 Ų62.84%0.03533%0.326CS..G310 helixtrans-73.2-12.4179.9-60.4-81.3000113.8F410 C414 M417 N421 V422 K523 F526F410-F419 HydrophobicContact CE1-CD1 4.09Å; F410-F419 AromaticContact CE1-CE1 3.77Å; F410-F419 HydrophobicContact CE1-CE1 3.77Å; F410-F419 AromaticContact CZ-CD1 3.75Å; F410-F419 HydrophobicContact CZ-CD1 3.75Å; F410-F419 AromaticContact CZ-CE1 3.78Å; F410-F419 HydrophobicContact CZ-CE1 3.78Å; C414-F419 HydrophobicContact CB-CD1 4.05Å; C414-F419 HydrophobicContact CB-CE1 4.37Å; M417-F419 HydrophobicContact CB-CD2 4.27Å; M417-F419 HydrophobicContact CB-CE2 3.76Å; M417-F419 HydrophobicContact CG-CE2 4.39Å; M417-F419 WeakPolarHBondContact O-CD2 3.39Å; M417-F419 PolarHBondContact O-N 2.96Å; M417-F419 HydrophobicContact SD-CE2 3.91Å; M417-F419 HydrophobicContact SD-CZ 3.88Å; F419-N421 PolarHBondContact O-N 2.85Å; F419-N421 VanDerWaalsContact O-N 3.15Å; F419-V422 WeakPolarHBondContact O-CB 3.26Å; F419-V422 WeakPolarHBondContact O-CG2 3.24Å; F419-V422 PolarHBondContact O-N 3.35Å; F419-K523 HydrophobicContact CE1-CD 4.08Å; F419-K523 HydrophobicContact CZ-CD 3.71Å; F419-K523 HydrophobicContact CZ-CG 4.47Å; F419-F526 HydrophobicContact CB-CD1 4.37Å; F419-F526 HydrophobicContact CB-CD2 4.08Å; F419-F526 HydrophobicContact CB-CE1 3.71Å; F419-F526 HydrophobicContact CB-CE2 3.34Å; F419-F526 HydrophobicContact CB-CZ 3.15Å; F419-F526 HydrophobicContact CD1-CD1 4.31Å; F419-F526 HydrophobicContact CD1-CE1 4.21Å; F419-F526 HydrophobicContact CD1-CZ 4.48Å; F419-F526 HydrophobicContact CD2-CD1 4.07Å; F419-F526 AromaticContact CD2-CD2 3.39Å; F419-F526 HydrophobicContact CD2-CD2 3.39Å; F419-F526 HydrophobicContact CD2-CE1 4.25Å; F419-F526 AromaticContact CD2-CE2 3.59Å; F419-F526 HydrophobicContact CD2-CE2 3.59Å; F419-F526 AromaticContact CD2-CG 3.67Å; F419-F526 HydrophobicContact CD2-CG 3.67Å; F419-F526 HydrophobicContact CD2-CZ 4.05Å; F419-F526 HydrophobicContact CE2-CB 4.33Å; F419-F526 HydrophobicContact CE2-CD1 4.42Å; F419-F526 HydrophobicContact CE2-CD2 4.02Å; F419-F526 AromaticContact CE2-CG 3.94Å; F419-F526 HydrophobicContact CE2-CG 3.94Å; F419-F526 HydrophobicContact CG-CD1 4.02Å; F419-F526 AromaticContact CG-CD2 3.93Å; F419-F526 HydrophobicContact CG-CD2 3.93Å; F419-F526 AromaticContact CG-CE1 3.83Å; F419-F526 HydrophobicContact CG-CE1 3.83Å; F419-F526 AromaticContact CG-CE2 3.72Å; F419-F526 HydrophobicContact CG-CE2 3.72Å; F419-F526 HydrophobicContact CG-CG 4.1Å; F419-F526 AromaticContact CG-CZ 3.7Å; F419-F526 HydrophobicContact CG-CZ 3.7Å
420E62.5Low73.4Confident153 Ų15366.1 Ų66.172%0.71534%0.339SS*.G310 helixtrans-49.4-32.5165.4-69.8150.2-133.900111.7K418 V422 Q423K418-E420 PolarHBondContact O-N 3.45Å; E420-V422 PolarHBondContact O-N 2.85Å; E420-Q423 WeakPolarHBondContact O-CB 3.27Å; E420-Q423 PolarHBondContact O-N 2.94Å
421N72.1Confident74.2Confident53 Ų5371.8 Ų71.828%0.28337%0.369SS..G310 helixtrans-68.6-2.8177.8-61.5-10.9000113.9H413 K418 F419 Q423 T424H413-N421 HydrophobicContact CB-CB 4.5Å; H413-N421 WeakPolarHBondContact O-CB 3.5Å; H413-N421 PolarHBondContact O-ND2 3.31Å; K418-N421 WeakPolarHBondContact O-CB 3.32Å; K418-N421 PolarHBondContact O-N 3.15Å; F419-N421 PolarHBondContact O-N 2.85Å; F419-N421 VanDerWaalsContact O-N 3.15Å; N421-Q423 VanDerWaalsContact C-N 3.27Å; N421-T424 WeakPolarHBondContact O-CB 3.33Å; N421-T424 PolarHBondContact O-N 3.48Å
422V77.1Confident75.3Confident7 Ų769.3 Ų69.34%0.04236%0.359CS..Hα-helixtrans-70.8-26.3163.5177.90000110.9F410 F419 E420 T424 L425 T426 V467 V468 A471F410-V422 HydrophobicContact CE2-CG2 3.99Å; F419-V422 WeakPolarHBondContact O-CB 3.26Å; F419-V422 WeakPolarHBondContact O-CG2 3.24Å; F419-V422 PolarHBondContact O-N 3.35Å; E420-V422 PolarHBondContact O-N 2.85Å; V422-T424 VanDerWaalsContact C-N 3.28Å; V422-T424 PolarHBondContact O-N 2.98Å; V422-L425 WeakPolarHBondContact O-CB 3.25Å; V422-L425 PolarHBondContact O-N 2.82Å; V422-L425 VanDerWaalsContact O-N 3.11Å; V422-T426 PolarHBondContact O-N 2.79Å; V422-T426 VanDerWaalsContact O-N 3.11Å; V422-T426 PolarHBondContact O-OG1 3.47Å; V422-V467 HydrophobicContact CG2-CG1 4.11Å; V422-V468 HydrophobicContact CG1-CG2 4.2Å; V422-A471 HydrophobicContact CG1-CB 3.78Å
423Q79.3Confident76.3Confident101 Ų10163.5 Ų63.547%0.47233%0.332SS..Hα-helixtrans-59.8-42171.3-168.461.34900110.5E420 N421 L425 T426 D427E420-Q423 WeakPolarHBondContact O-CB 3.27Å; E420-Q423 PolarHBondContact O-N 2.94Å; N421-Q423 VanDerWaalsContact C-N 3.27Å; Q423-L425 PolarHBondContact O-N 3.49Å; Q423-T426 WeakPolarHBondContact CA-OG1 3.46Å; Q423-T426 PolarHBondContact NE2-OG1 3.08Å; Q423-T426 CarbonylContact O-C 3.54Å; Q423-T426 PolarHBondContact O-N 3.34Å; Q423-T426 PolarHBondContact O-OG1 3.36Å; Q423-D427 PolarHBondContact NE2-OD1 3.06Å; Q423-D427 WeakPolarHBondContact O-CB 3.4Å; Q423-D427 PolarHBondContact O-N 2.99Å
424T84.6Confident77.4Confident78 Ų7865.2 Ų65.248%0.47934%0.341SS..Hα-helixtrans-57-33.3175-43.50000112.9N421 V422 A428N421-T424 WeakPolarHBondContact O-CB 3.33Å; N421-T424 PolarHBondContact O-N 3.48Å; V422-T424 VanDerWaalsContact C-N 3.28Å; V422-T424 PolarHBondContact O-N 2.98Å; T424-A428 VanDerWaalsContact O-CB 3.25Å; T424-A428 WeakPolarHBondContact O-CB 3.36Å; T424-A428 PolarHBondContact O-N 2.92Å
425L87.4Confident78.7Confident5 Ų568.6 Ų68.63%0.02636%0.359CS..Hα-helixtrans-70.5-48.9172.1174.562.3000111.2I375 V406 F408 V422 Q423 D427 A428 I429 V468I375-L425 HydrophobicContact CG2-CD2 4.07Å; V406-L425 HydrophobicContact CG1-CD1 4.2Å; F408-L425 HydrophobicContact CB-CD1 4.17Å; F408-L425 HydrophobicContact CB-CD2 4.37Å; F408-L425 HydrophobicContact CD1-CD2 3.99Å; F408-L425 HydrophobicContact CD2-CB 4.01Å; F408-L425 HydrophobicContact CD2-CD1 3.99Å; F408-L425 HydrophobicContact CD2-CD2 4.36Å; F408-L425 HydrophobicContact CD2-CG 4.34Å; F408-L425 HydrophobicContact CE1-CD2 4.33Å; F408-L425 HydrophobicContact CE2-CB 3.81Å; F408-L425 HydrophobicContact CG-CB 4.46Å; F408-L425 HydrophobicContact CG-CD1 4.13Å; F408-L425 HydrophobicContact CG-CD2 3.99Å; F408-L425 HydrophobicContact CG-CG 4.42Å; F408-L425 HydrophobicContact CZ-CB 4.07Å; V422-L425 WeakPolarHBondContact O-CB 3.25Å; V422-L425 PolarHBondContact O-N 2.82Å; V422-L425 VanDerWaalsContact O-N 3.11Å; Q423-L425 PolarHBondContact O-N 3.49Å; L425-D427 VanDerWaalsContact C-N 3.31Å; L425-D427 PolarHBondContact O-N 2.91Å; L425-A428 PolarHBondContact O-N 2.67Å; L425-I429 HydrophobicContact CD1-CG2 4.35Å; L425-I429 HydrophobicContact CG-CD1 4.49Å; L425-I429 WeakPolarHBondContact O-CG1 3.37Å; L425-I429 PolarHBondContact O-N 3.28Å; L425-I429 VanDerWaalsContact O-N 3.15Å; L425-V468 HydrophobicContact CD2-CG1 3.9Å; L425-V468 HydrophobicContact CD2-CG2 4.32Å
426T88.9Confident80.3Confident1 Ų158.9 Ų58.91%0.00632%0.322CS..Hα-helixtrans-65.4-32.5-179.8460000113.2V422 Q423 I429 Y430 I433 A471 I472V422-T426 PolarHBondContact O-N 2.79Å; V422-T426 VanDerWaalsContact O-N 3.11Å; V422-T426 PolarHBondContact O-OG1 3.47Å; Q423-T426 WeakPolarHBondContact CA-OG1 3.46Å; Q423-T426 PolarHBondContact NE2-OG1 3.08Å; Q423-T426 CarbonylContact O-C 3.54Å; Q423-T426 PolarHBondContact O-N 3.34Å; Q423-T426 PolarHBondContact O-OG1 3.36Å; T426-I429 CarbonylContact O-C 3.59Å; T426-Y430 VanDerWaalsContact O-CA 3.3Å; T426-Y430 WeakPolarHBondContact O-CA 3.07Å; T426-Y430 WeakPolarHBondContact O-CB 3.48Å; T426-Y430 PolarHBondContact O-N 2.96Å; T426-I433 HydrophobicContact CG2-CD1 4.44Å; T426-A471 HydrophobicContact CG2-CB 3.89Å; T426-I472 HydrophobicContact CG2-CG1 4.04Å
427D88.3Confident82.2Confident88 Ų8859.4 Ų59.447%0.47130%0.304SS..Hα-helixtrans-67.8-46.3174.3-59.2-19.7000110.3Q423 L425 I429 Y430Q423-D427 PolarHBondContact NE2-OD1 3.06Å; Q423-D427 WeakPolarHBondContact O-CB 3.4Å; Q423-D427 PolarHBondContact O-N 2.99Å; L425-D427 VanDerWaalsContact C-N 3.31Å; L425-D427 PolarHBondContact O-N 2.91Å; D427-I429 PolarHBondContact O-N 3.43Å; D427-Y430 VanDerWaalsContact O-CB 3.29Å; D427-Y430 WeakPolarHBondContact O-CB 3.28Å; D427-Y430 PolarHBondContact O-N 3.17Å; D427-Y430 VanDerWaalsContact O-N 3.16Å
428A89.1Confident84.2Confident69 Ų6955.9 Ų55.957%0.5729%0.286SS*.Hα-helixtrans-66.9-18.1179.500000114.2T424 L425T424-A428 VanDerWaalsContact O-CB 3.25Å; T424-A428 WeakPolarHBondContact O-CB 3.36Å; T424-A428 PolarHBondContact O-N 2.92Å; L425-A428 PolarHBondContact O-N 2.67Å
429I91.9Very high86Confident1 Ų149.9 Ų49.91%0.00526%0.26CS..THydrogen-bonded Turntrans-114.914.3174.273.6-176.6000112.6I375 V406 L425 T426 D427 D431 I432 I433 F454 I472I375-I429 HydrophobicContact CD1-CD1 3.69Å; V406-I429 HydrophobicContact CG1-CG2 4.4Å; L425-I429 HydrophobicContact CD1-CG2 4.35Å; L425-I429 HydrophobicContact CG-CD1 4.49Å; L425-I429 WeakPolarHBondContact O-CG1 3.37Å; L425-I429 PolarHBondContact O-N 3.28Å; L425-I429 VanDerWaalsContact O-N 3.15Å; T426-I429 CarbonylContact O-C 3.59Å; D427-I429 PolarHBondContact O-N 3.43Å; I429-D431 PolarHBondContact O-N 2.93Å; I429-I432 HydrophobicContact CB-CB 4.36Å; I429-I432 HydrophobicContact CB-CD1 4.24Å; I429-I432 HydrophobicContact CG2-CD1 4.37Å; I429-I432 CarbonylContact O-C 3.6Å; I429-I432 WeakPolarHBondContact O-CA 3.4Å; I429-I432 VanDerWaalsContact O-CB 3.29Å; I429-I432 WeakPolarHBondContact O-CB 3.29Å; I429-I432 PolarHBondContact O-N 3.28Å; I429-I433 HydrophobicContact CD1-CD1 4.34Å; I429-I433 HydrophobicContact CD1-CG1 4.46Å; I429-I433 HydrophobicContact CG1-CD1 3.87Å; I429-I433 HydrophobicContact CG1-CG1 4.06Å; I429-I433 WeakPolarHBondContact O-CG1 3.41Å; I429-I433 PolarHBondContact O-N 3.41Å; I429-F454 HydrophobicContact CD1-CD1 4.48Å; I429-F454 HydrophobicContact CD1-CE1 3.98Å; I429-I472 HydrophobicContact CD1-CD1 4.29Å
430Y91.5Very high87.9Confident80 Ų8051.7 Ų51.731%0.31427%0.267SS..Hα-helixtrans-58.8-47-170.7-178.3-99.4000112.9T426 D427 I432 I433 L434 V475 Q479T426-Y430 VanDerWaalsContact O-CA 3.3Å; T426-Y430 WeakPolarHBondContact O-CA 3.07Å; T426-Y430 WeakPolarHBondContact O-CB 3.48Å; T426-Y430 PolarHBondContact O-N 2.96Å; D427-Y430 VanDerWaalsContact O-CB 3.29Å; D427-Y430 WeakPolarHBondContact O-CB 3.28Å; D427-Y430 PolarHBondContact O-N 3.17Å; D427-Y430 VanDerWaalsContact O-N 3.16Å; Y430-I432 PolarHBondContact O-N 2.96Å; Y430-I433 WeakPolarHBondContact O-CB 3.44Å; Y430-I433 PolarHBondContact O-N 2.92Å; Y430-L434 HydrophobicContact CD1-CD1 4.12Å; Y430-L434 HydrophobicContact CE1-CD1 3.59Å; Y430-L434 HydrophobicContact CE1-CG 4.23Å; Y430-L434 PolarHBondContact O-N 3.26Å; Y430-L434 VanDerWaalsContact O-N 3.08Å; Y430-V475 HydrophobicContact CD2-CG1 3.97Å; Y430-V475 HydrophobicContact CE2-CG1 3.75Å; Y430-Q479 PolarHBondContact OH-NE2 3.44Å
431D91.6Very high89.4Confident124 Ų12445.2 Ų45.266%0.66324%0.238SC*.Hα-helixtrans-63.3-32.5177-57.6-40.5000111.9I429 L434 D435I429-D431 PolarHBondContact O-N 2.93Å; D431-L434 PolarHBondContact O-N 3.02Å; D431-D435 WeakPolarHBondContact O-CB 3.18Å; D431-D435 PolarHBondContact O-N 3.17Å
432I93.1Very high90.4Very high38 Ų3845 Ų4520%0.19524%0.237CC..Hα-helixtrans-69-38.5174.8-51.8178000110.3V373 I429 Y430 L434 D435 M436 F454 I895V373-I432 HydrophobicContact CG2-CG2 3.86Å; I429-I432 HydrophobicContact CB-CB 4.36Å; I429-I432 HydrophobicContact CB-CD1 4.24Å; I429-I432 HydrophobicContact CG2-CD1 4.37Å; I429-I432 CarbonylContact O-C 3.6Å; I429-I432 WeakPolarHBondContact O-CA 3.4Å; I429-I432 VanDerWaalsContact O-CB 3.29Å; I429-I432 WeakPolarHBondContact O-CB 3.29Å; I429-I432 PolarHBondContact O-N 3.28Å; Y430-I432 PolarHBondContact O-N 2.96Å; I432-L434 VanDerWaalsContact C-N 3.3Å; I432-L434 PolarHBondContact O-N 2.85Å; I432-D435 PolarHBondContact O-N 3.05Å; I432-M436 HydrophobicContact CG2-CE 3.77Å; I432-M436 WeakPolarHBondContact O-CG 3.32Å; I432-M436 PolarHBondContact O-N 2.95Å; I432-M436 VanDerWaalsContact O-N 3.08Å; I432-F454 HydrophobicContact CG2-CE1 4.13Å; I432-F454 HydrophobicContact CG2-CZ 4.09Å; I432-I895 HydrophobicContact CD1-CD1 3.68Å
433I92.8Very high90.9Very high2 Ų252.1 Ų52.11%0.0127%0.269CS..Hα-helixtrans-62-39.7174.4-65.9169.4000110.7T426 I429 Y430 F454 I472 V475 V476T426-I433 HydrophobicContact CG2-CD1 4.44Å; I429-I433 HydrophobicContact CD1-CD1 4.34Å; I429-I433 HydrophobicContact CD1-CG1 4.46Å; I429-I433 HydrophobicContact CG1-CD1 3.87Å; I429-I433 HydrophobicContact CG1-CG1 4.06Å; I429-I433 WeakPolarHBondContact O-CG1 3.41Å; I429-I433 PolarHBondContact O-N 3.41Å; Y430-I433 WeakPolarHBondContact O-CB 3.44Å; Y430-I433 PolarHBondContact O-N 2.92Å; I433-F454 HydrophobicContact CB-CE2 4.37Å; I433-F454 HydrophobicContact CB-CZ 4.27Å; I433-F454 HydrophobicContact CG1-CE1 4.45Å; I433-F454 HydrophobicContact CG1-CE2 3.82Å; I433-F454 HydrophobicContact CG1-CZ 3.54Å; I433-I472 HydrophobicContact CD1-CG1 4.37Å; I433-I472 HydrophobicContact CD1-CG2 4.16Å; I433-I472 HydrophobicContact CG1-CG2 4.19Å; I433-V475 HydrophobicContact CD1-CG1 4.43Å; I433-V475 HydrophobicContact CG2-CG1 4.11Å; I433-V476 HydrophobicContact CG2-CG2 3.47Å; I433-V476 VanDerWaalsContact CG2-CG2 3.47Å
434L89Confident91.3Very high67 Ų6752 Ų5235%0.35129%0.285SS..Hα-helixtrans-68.9-40.7176.1-63.1-178.6000112.4Y430 D431 I432 M436 K437 Q479Y430-L434 HydrophobicContact CD1-CD1 4.12Å; Y430-L434 HydrophobicContact CE1-CD1 3.59Å; Y430-L434 HydrophobicContact CE1-CG 4.23Å; Y430-L434 PolarHBondContact O-N 3.26Å; Y430-L434 VanDerWaalsContact O-N 3.08Å; D431-L434 PolarHBondContact O-N 3.02Å; I432-L434 VanDerWaalsContact C-N 3.3Å; I432-L434 PolarHBondContact O-N 2.85Å; L434-M436 PolarHBondContact O-N 3.05Å; L434-K437 PolarHBondContact O-N 3.08Å; L434-Q479 HydrophobicContact CD2-CG 4.2Å
435D91.5Very high91.6Very high81 Ų8149.6 Ų49.643%0.43328%0.276SS..Hα-helixtrans-63.9-35.117817570.8000113.7K371 D431 I432 K437K371-D435 IonicContact NZ-OD2 3.96Å; K371-D435 PolarHBondContact NZ-OD2 3.14Å; D431-D435 WeakPolarHBondContact O-CB 3.18Å; D431-D435 PolarHBondContact O-N 3.17Å; I432-D435 PolarHBondContact O-N 3.05Å; D435-K437 PolarHBondContact O-N 2.98Å
436M91.2Very high91.8Very high0 Ų051.6 Ų51.60%029%0.289CS..THydrogen-bonded Turntrans-61-24.9174.9-67.4-55.3113.800113.3K371 V373 I432 L434 Q450 E451 G452 F454K371-M436 HydrophobicContact CD-CE 3.72Å; K371-M436 HydrophobicContact CG-CE 4.21Å; V373-M436 HydrophobicContact CG2-CE 3.66Å; V373-M436 HydrophobicContact CG2-SD 4.13Å; I432-M436 HydrophobicContact CG2-CE 3.77Å; I432-M436 WeakPolarHBondContact O-CG 3.32Å; I432-M436 PolarHBondContact O-N 2.95Å; I432-M436 VanDerWaalsContact O-N 3.08Å; L434-M436 PolarHBondContact O-N 3.05Å; M436-Q450 WeakPolarHBondContact O-CG 3.48Å; M436-E451 PolarHBondContact O-N 2.87Å; M436-G452 WeakPolarHBondContact SD-CA 3.48Å; M436-F454 HydrophobicContact CB-CE2 4.34Å; M436-F454 HydrophobicContact CG-CD2 4.28Å; M436-F454 HydrophobicContact CG-CE2 3.57Å; M436-F454 HydrophobicContact CG-CZ 3.82Å
437K93.6Very high92.1Very high82 Ų8255.6 Ų55.636%0.35731%0.309SS..  trans54-160.4-170.2-46.3178.8-158.1161.40112.3L434 D435 E451L434-K437 PolarHBondContact O-N 3.08Å; D435-K437 PolarHBondContact O-N 2.98Å; K437-E451 HydrophobicContact CD-CG 3.83Å; K437-E451 HydrophobicContact CG-CG 4.41Å; K437-E451 VanDerWaalsContact NZ-CG 3.33Å; K437-E451 IonicContact NZ-OE1 2.75Å; K437-E451 PolarHBondContact NZ-OE1 3.27Å
438W95.8Very high92.4Very high9 Ų953 Ų533%0.03430%0.298CS..  trans-149.5161.4172.854.487.8000108.7F323 C448 K449 V476 Q479 Q480 K483F323-W438 HydrophobicContact CB-CB 4.44Å; W438-C448 PolarHBondContact O-SG 3.05Å; W438-C448 VanDerWaalsContact O-SG 3.33Å; W438-K449 CarbonylContact O-C 3.54Å; W438-V476 HydrophobicContact CB-CG1 4.31Å; W438-V476 HydrophobicContact CD2-CG1 4.32Å; W438-V476 HydrophobicContact CE3-CG1 3.9Å; W438-Q479 HydrophobicContact CH2-CB 3.82Å; W438-Q479 HydrophobicContact CZ3-CB 4.1Å; W438-Q480 HydrophobicContact CD2-CG 3.84Å; W438-Q480 HydrophobicContact CE3-CG 4.43Å; W438-Q480 HydrophobicContact CG-CG 4.05Å; W438-Q480 VanDerWaalsContact CG-NE2 3.32Å; W438-Q480 HydrophobicContact CH2-CG 4.48Å; W438-Q480 HydrophobicContact CZ2-CG 3.91Å; W438-K483 HydrophobicContact CH2-CD 4.06Å; W438-K483 HydrophobicContact CZ2-CD 3.77Å; W438-K483 HydrophobicContact CZ2-CG 4.41Å
439C97.1Very high92.7Very high0 Ų054.3 Ų54.30%029%0.291CS..EExtended strand (participates in β ladder)trans-74.6136.8171.2-171.90000109.8Q189 L321 S322 C448Q189-C439 HydrophobicContact CB-CB 3.89Å; Q189-C439 HydrophobicContact CG-CB 4.44Å; L321-C439 CarbonylContact C-O 3.59Å; L321-C439 VanDerWaalsContact CA-O 3.26Å; L321-C439 WeakPolarHBondContact CA-O 3.29Å; S322-C439 PolarHBondContact N-O 3.05Å; S322-C439 PolarHBondContact O-N 3.05Å; C439-C448 CarbonylContact C-O 3.25Å; C439-C448 WeakPolarHBondContact CA-O 3.48Å
440W96.9Very high92.9Very high46 Ų4654.8 Ų54.817%0.17429%0.293CS..EExtended strand (participates in β ladder)trans-135.5123.2172.7-173.4-2.1000107.9H319 L321 V446 I447 C448 L484H319-W440 AromaticContact CG-NE1 3.5Å; H319-W440 AromaticContact ND1-NE1 3.36Å; H319-W440 PolarHBondContact ND1-NE1 2.79Å; L321-W440 HydrophobicContact CD1-CD2 4.43Å; L321-W440 HydrophobicContact CD1-CG 3.97Å; L321-W440 HydrophobicContact CD2-CD2 4.31Å; L321-W440 HydrophobicContact CD2-CG 4.26Å; L321-W440 HydrophobicContact CG-CB 4.1Å; L321-W440 HydrophobicContact CG-CD2 4.28Å; L321-W440 HydrophobicContact CG-CG 3.75Å; W440-V446 CarbonylContact O-C 3.47Å; W440-I447 HydrophobicContact CB-CB 4.3Å; W440-I447 HydrophobicContact CD2-CB 4.37Å; W440-I447 HydrophobicContact CD2-CD1 4.01Å; W440-I447 HydrophobicContact CD2-CG2 4.2Å; W440-I447 HydrophobicContact CE3-CG2 4.1Å; W440-I447 HydrophobicContact CG-CB 4.18Å; W440-I447 HydrophobicContact CG-CD1 3.97Å; W440-I447 HydrophobicContact CG-CG2 4.5Å; W440-I447 HydrophobicContact CZ2-CD1 4.39Å; W440-I447 PolarHBondContact O-N 3.48Å; W440-C448 HydrophobicContact CB-CB 3.77Å; W440-C448 PolarHBondContact N-O 2.93Å; W440-C448 PolarHBondContact O-N 2.86Å; W440-C448 VanDerWaalsContact O-N 3.08Å; W440-L484 HydrophobicContact CZ2-CD2 3.88Å
441V95.3Very high93Very high18 Ų1854.9 Ų54.911%0.10930%0.296CS..EExtended strand (participates in β ladder)trans-124.8146.1-178.2-170.90000109.3V188 H319 T320 G445 V446V188-V441 HydrophobicContact CG1-CB 4.5Å; V188-V441 HydrophobicContact CG1-CG2 3.79Å; H319-V441 WeakPolarHBondContact CA-O 3.37Å; T320-V441 PolarHBondContact N-O 2.81Å; T320-V441 PolarHBondContact O-N 2.75Å; V441-G445 CarbonylContact C-O 3.58Å; V441-G445 VanDerWaalsContact CA-O 3.27Å; V441-G445 WeakPolarHBondContact CA-O 3.4Å; V441-G445 WeakPolarHBondContact CG1-O 3.31Å; V441-V446 HydrophobicContact CG2-CG2 4.28Å
442D93.3Very high93.1Very high48 Ų4849 Ų4926%0.25726%0.264SS..  trans-137.2-166.6169.674.4-3.3000111.2N318 H319 A444 G445 I447N318-D442 WeakPolarHBondContact O-CA 3.46Å; H319-D442 IonicContact CE1-OD2 2.84Å; H319-D442 WeakPolarHBondContact ND1-CB 3.47Å; D442-A444 VanDerWaalsContact C-N 3.3Å; D442-A444 PolarHBondContact O-N 2.91Å; D442-A444 WeakPolarHBondContact OD1-CA 3.37Å; D442-A444 WeakPolarHBondContact OD1-CB 3.33Å; D442-A444 PolarHBondContact OD1-N 3.31Å; D442-G445 PolarHBondContact N-O 3.45Å; D442-G445 PolarHBondContact O-N 2.79Å; D442-G445 PolarHBondContact OD1-N 3.21Å; D442-I447 HydrophobicContact CB-CD1 3.85Å
443E87.5Confident93.3Very high156 Ų15647.3 Ų47.373%0.72926%0.256SS*.SBendtrans-68-25.2177.7-71171.3134.200114N318N318-E443 HydrophobicContact CB-CG 4.1Å; N318-E443 PolarHBondContact ND2-OE1 2.96Å; N318-E443 PolarHBondContact ND2-OE2 2.69Å
444A88.1Confident93.5Very high98 Ų9847.2 Ų47.281%0.8126%0.256SS*.SBendtrans-82-30.9176.600000111.7D442D442-A444 VanDerWaalsContact C-N 3.3Å; D442-A444 PolarHBondContact O-N 2.91Å; D442-A444 WeakPolarHBondContact OD1-CA 3.37Å; D442-A444 WeakPolarHBondContact OD1-CB 3.33Å; D442-A444 PolarHBondContact OD1-N 3.31Å
445G89.2Confident93.8Very high28 Ų2844 Ų4429%0.28924%0.239SC..  trans148.7-141.3168.600000113.7V441 D442 I447V441-G445 CarbonylContact C-O 3.58Å; V441-G445 VanDerWaalsContact CA-O 3.27Å; V441-G445 WeakPolarHBondContact CA-O 3.4Å; V441-G445 WeakPolarHBondContact CG1-O 3.31Å; D442-G445 PolarHBondContact N-O 3.45Å; D442-G445 PolarHBondContact O-N 2.79Å; D442-G445 PolarHBondContact OD1-N 3.21Å; G445-I447 PolarHBondContact O-N 3.06Å
446V93.3Very high94Very high48 Ų4840.2 Ų40.229%0.29122%0.218SC..EExtended strand (participates in β ladder)trans-88.2100.5-178.2-175.30000110.2S192 W440 V441 C448 K449S192-V446 WeakPolarHBondContact O-CG2 3.32Å; W440-V446 CarbonylContact O-C 3.47Å; V441-V446 HydrophobicContact CG2-CG2 4.28Å; V446-C448 VanDerWaalsContact CG1-O 3.25Å; V446-C448 WeakPolarHBondContact CG1-O 3.48Å; V446-K449 HydrophobicContact CG1-CD 4.47Å; V446-K449 HydrophobicContact CG1-CG 3.67Å
447I94.6Very high93.9Very high85 Ų8540.2 Ų40.244%0.43622%0.218SC..EExtended strand (participates in β ladder)trans-66.5-43.6174-60.7160.1000110.9W440 D442 G445W440-I447 HydrophobicContact CB-CB 4.3Å; W440-I447 HydrophobicContact CD2-CB 4.37Å; W440-I447 HydrophobicContact CD2-CD1 4.01Å; W440-I447 HydrophobicContact CD2-CG2 4.2Å; W440-I447 HydrophobicContact CE3-CG2 4.1Å; W440-I447 HydrophobicContact CG-CB 4.18Å; W440-I447 HydrophobicContact CG-CD1 3.97Å; W440-I447 HydrophobicContact CG-CG2 4.5Å; W440-I447 HydrophobicContact CZ2-CD1 4.39Å; W440-I447 PolarHBondContact O-N 3.48Å; D442-I447 HydrophobicContact CB-CD1 3.85Å; G445-I447 PolarHBondContact O-N 3.06Å
448C94.5Very high93.4Very high34 Ų3437 Ų3723%0.2321%0.206CC..EExtended strand (participates in β ladder)trans-142.3148.6-175.1-166.20000111.1W438 C439 W440 V446W438-C448 PolarHBondContact O-SG 3.05Å; W438-C448 VanDerWaalsContact O-SG 3.33Å; C439-C448 CarbonylContact C-O 3.25Å; C439-C448 WeakPolarHBondContact CA-O 3.48Å; W440-C448 HydrophobicContact CB-CB 3.77Å; W440-C448 PolarHBondContact N-O 2.93Å; W440-C448 PolarHBondContact O-N 2.86Å; W440-C448 VanDerWaalsContact O-N 3.08Å; V446-C448 VanDerWaalsContact CG1-O 3.25Å; V446-C448 WeakPolarHBondContact CG1-O 3.48Å
449K95.1Very high92.4Very high96 Ų9636.7 Ų36.742%0.41721%0.205SC..  trans-116.5144.1172.3-65.9179.2-174.8178.10109.7Q189 T193 W438 V446Q189-K449 VanDerWaalsContact OE1-CA 3.3Å; T193-K449 HydrophobicContact CG2-CD 4.36Å; W438-K449 CarbonylContact O-C 3.54Å; V446-K449 HydrophobicContact CG1-CD 4.47Å; V446-K449 HydrophobicContact CG1-CG 3.67Å
450Q95.9Very high90.7Very high11 Ų1137.2 Ų37.25%0.05121%0.208CC..  trans-73.8121.7163.7-171.1171.4-8.300108.2Q189 V324 M436 G452Q189-Q450 PolarHBondContact NE2-O 2.99Å; V324-Q450 PolarHBondContact O-NE2 2.82Å; M436-Q450 WeakPolarHBondContact O-CG 3.48Å; Q450-G452 WeakPolarHBondContact CG-O 3.26Å; Q450-G452 PolarHBondContact NE2-O 3.5Å
451E93.8Very high88.9Confident81 Ų8136.2 Ų36.238%0.37921%0.207SC..  trans-96.1-6.4-174.6-51.3-68.5-173.600112.8K371 M436 K437K371-E451 WeakPolarHBondContact CB-O 3.33Å; K371-E451 PolarHBondContact N-O 2.78Å; M436-E451 PolarHBondContact O-N 2.87Å; K437-E451 HydrophobicContact CD-CG 3.83Å; K437-E451 HydrophobicContact CG-CG 4.41Å; K437-E451 VanDerWaalsContact NZ-CG 3.33Å; K437-E451 IonicContact NZ-OE1 2.75Å; K437-E451 PolarHBondContact NZ-OE1 3.27Å
452G94.7Very high87.5Confident0 Ų036.3 Ų36.30%021%0.207CC..EExtended strand (participates in β ladder)trans-168.9166.9176.200000114Y369 K371 M436 Q450Y369-G452 WeakPolarHBondContact O-CA 3.05Å; K371-G452 CarbonylContact O-C 3.58Å; K371-G452 WeakPolarHBondContact O-CA 3.45Å; M436-G452 WeakPolarHBondContact SD-CA 3.48Å; Q450-G452 WeakPolarHBondContact CG-O 3.26Å; Q450-G452 PolarHBondContact NE2-O 3.5Å
453I96.4Very high86.5Confident4 Ų434.5 Ų34.52%0.02120%0.198CC..EExtended strand (participates in β ladder)trans-129.2150.6-176.262.7163.1000113.1V324 T326 Y369 K371 Q372 V373V324-I453 HydrophobicContact CB-CG2 4.47Å; V324-I453 HydrophobicContact CG1-CG2 4.47Å; T326-I453 HydrophobicContact CG2-CD1 3.43Å; T326-I453 VanDerWaalsContact CG2-CD1 3.43Å; Y369-I453 HydrophobicContact CD1-CD1 3.71Å; Y369-I453 HydrophobicContact CD1-CG1 4.26Å; Y369-I453 HydrophobicContact CD1-CG2 3.74Å; Y369-I453 HydrophobicContact CD2-CD1 3.5Å; Y369-I453 VanDerWaalsContact CD2-CD1 3.5Å; Y369-I453 HydrophobicContact CD2-CG1 4.33Å; Y369-I453 HydrophobicContact CE1-CD1 4.12Å; Y369-I453 HydrophobicContact CE2-CD1 3.96Å; Y369-I453 HydrophobicContact CG-CD1 3.39Å; Y369-I453 HydrophobicContact CG-CG1 3.86Å; Y369-I453 HydrophobicContact CG-CG2 4.13Å; K371-I453 PolarHBondContact O-N 3.21Å; Q372-I453 WeakPolarHBondContact CA-O 3.23Å; Q372-I453 HydrophobicContact CG-CG1 4.32Å; V373-I453 PolarHBondContact N-O 3.42Å
454F97.3Very high86.4Confident0 Ų027.5 Ų27.50%016%0.164CC..EExtended strand (participates in β ladder)trans-84.4131.4164.8-64.3-81.6000110.4F323 Q325 T326 V373 I375 I429 I432 I433 M436 I472F323-F454 HydrophobicContact CZ-CD2 4.08Å; F323-F454 HydrophobicContact CZ-CE2 4.45Å; Q325-F454 HydrophobicContact CG-CB 4.48Å; T326-F454 PolarHBondContact N-O 3.33Å; V373-F454 HydrophobicContact CB-CD1 3.7Å; V373-F454 HydrophobicContact CB-CE1 3.88Å; V373-F454 HydrophobicContact CG1-CD1 3.88Å; V373-F454 HydrophobicContact CG1-CE1 3.88Å; V373-F454 HydrophobicContact CG2-CD1 4.4Å; V373-F454 HydrophobicContact CG2-CE1 4.16Å; V373-F454 WeakPolarHBondContact O-CA 3.41Å; I375-F454 HydrophobicContact CD1-CB 4.5Å; I375-F454 HydrophobicContact CD1-CD1 3.71Å; I375-F454 HydrophobicContact CD1-CE1 4.4Å; I375-F454 HydrophobicContact CD1-CG 4.41Å; I375-F454 HydrophobicContact CG1-CD1 4.26Å; I429-F454 HydrophobicContact CD1-CD1 4.48Å; I429-F454 HydrophobicContact CD1-CE1 3.98Å; I432-F454 HydrophobicContact CG2-CE1 4.13Å; I432-F454 HydrophobicContact CG2-CZ 4.09Å; I433-F454 HydrophobicContact CB-CE2 4.37Å; I433-F454 HydrophobicContact CB-CZ 4.27Å; I433-F454 HydrophobicContact CG1-CE1 4.45Å; I433-F454 HydrophobicContact CG1-CE2 3.82Å; I433-F454 HydrophobicContact CG1-CZ 3.54Å; M436-F454 HydrophobicContact CB-CE2 4.34Å; M436-F454 HydrophobicContact CG-CD2 4.28Å; M436-F454 HydrophobicContact CG-CE2 3.57Å; M436-F454 HydrophobicContact CG-CZ 3.82Å; F454-I472 HydrophobicContact CB-CD1 4.34Å; F454-I472 HydrophobicContact CD1-CD1 4.37Å; F454-I472 HydrophobicContact CD2-CG2 3.72Å; F454-I472 HydrophobicContact CE2-CG2 3.92Å; F454-I472 HydrophobicContact CG-CD1 4.17Å; F454-I472 HydrophobicContact CG-CG2 4.33Å
455R96Very high86.4Confident0 Ų023.2 Ų23.20%013%0.128CC..EExtended strand (participates in β ladder)trans-115.396.9176.8-173.2-123.3-175.893.9-1.3109T326 H361 Q372 V373 I374 I375 N457T326-R455 WeakPolarHBondContact O-CA 3.43Å; T326-R455 WeakPolarHBondContact OG1-CB 3.49Å; T326-R455 WeakPolarHBondContact OG1-CG 3.36Å; H361-R455 PolarHBondContact NE2-NH1 3.22Å; H361-R455 PolarHBondContact NE2-NH2 2.96Å; Q372-R455 HydrophobicContact CG-CB 3.72Å; Q372-R455 VanDerWaalsContact OE1-CD 3.3Å; V373-R455 PolarHBondContact O-N 3.19Å; I374-R455 WeakPolarHBondContact CA-O 3.17Å; I375-R455 PolarHBondContact N-O 3.34Å; R455-N457 VanDerWaalsContact CD-OD1 3.25Å; R455-N457 WeakPolarHBondContact CD-OD1 3.39Å; R455-N457 PolarHBondContact NE-OD1 3.36Å; R455-N457 PolarHBondContact O-N 3.3Å
456V94.1Very high86.5Confident0 Ų022 Ų220%012%0.115CC..EExtended strand (participates in β ladder)trans-89.7109.6-172.1-170.60000110.1T326 R327 I375 L377 T465 V468 Q469T326-V456 PolarHBondContact O-N 2.96Å; R327-V456 WeakPolarHBondContact CB-O 3.43Å; I375-V456 HydrophobicContact CB-CG2 4.49Å; L377-V456 HydrophobicContact CD1-CG1 3.61Å; L377-V456 HydrophobicContact CG-CG1 4.11Å; V456-T465 HydrophobicContact CG1-CG2 4.09Å; V456-V468 HydrophobicContact CG1-CB 4.13Å; V456-V468 HydrophobicContact CG1-CG1 4.09Å; V456-V468 HydrophobicContact CG2-CG1 4.32Å; V456-Q469 HydrophobicContact CB-CG 4.08Å; V456-Q469 HydrophobicContact CG2-CG 3.67Å
457N89.8Confident86.2Confident0 Ų020.5 Ų20.50%011%0.106CC..EExtended strand (participates in β ladder)trans-102.9149.4-178-82.221.1000111.9I375 L377 Y391 R455I375-N457 PolarHBondContact O-N 3.22Å; L377-N457 WeakPolarHBondContact CB-O 3.18Å; L377-N457 PolarHBondContact N-O 3.03Å; Y391-N457 HydrophobicContact CE1-CB 4.15Å; Y391-N457 WeakPolarHBondContact CE1-ND2 3.47Å; Y391-N457 PolarHBondContact OH-ND2 2.72Å; R455-N457 VanDerWaalsContact CD-OD1 3.25Å; R455-N457 WeakPolarHBondContact CD-OD1 3.39Å; R455-N457 PolarHBondContact NE-OD1 3.36Å; R455-N457 PolarHBondContact O-N 3.3Å
458C82.2Confident86.1Confident14 Ų1416.5 Ų16.510%0.0959%0.085CC..  trans-155.6145173.2179.20000109L377 C461 R464 T465L377-C458 HydrophobicContact CB-CB 4.42Å; C458-C461 PolarHBondContact SG-N 2.91Å; C458-R464 HydrophobicContact CB-CB 4.45Å; C458-R464 PolarHBondContact SG-NE 2.85Å; C458-R464 PolarHBondContact SG-NH2 2.99Å; C458-T465 HydrophobicContact CB-CG2 3.44Å; C458-T465 VanDerWaalsContact CB-CG2 3.44Å
459M74.8Confident86.1Confident4 Ų414.9 Ų14.92%0.027%0.074CC..SBendtrans-68.4-46176.6-164-175.697.200112R296 W334 P345 V378 E384 I387R296-M459 PolarHBondContact NH1-O 3.35Å; W334-M459 HydrophobicContact CH2-CB 4.42Å; W334-M459 HydrophobicContact CH2-CG 3.3Å; W334-M459 HydrophobicContact CH2-SD 4.33Å; W334-M459 HydrophobicContact CZ2-CG 4.24Å; W334-M459 HydrophobicContact CZ3-CG 3.69Å; W334-M459 HydrophobicContact CZ3-SD 4.13Å; P345-M459 HydrophobicContact CB-CE 4.23Å; P345-M459 HydrophobicContact CB-SD 3.96Å; P345-M459 HydrophobicContact CG-CE 3.92Å; P345-M459 HydrophobicContact CG-SD 3.74Å; V378-M459 HydrophobicContact CG2-CB 4.17Å; E384-M459 VanDerWaalsContact CA-SD 3.6Å; E384-M459 HydrophobicContact CB-CB 4.08Å; E384-M459 HydrophobicContact CB-CE 4.45Å; E384-M459 HydrophobicContact CB-CG 4.49Å; E384-M459 HydrophobicContact CB-SD 3.69Å; E384-M459 HydrophobicContact CG-CB 4.04Å; E384-M459 HydrophobicContact CG-CE 3.9Å; E384-M459 HydrophobicContact CG-CG 4.49Å; E384-M459 HydrophobicContact CG-SD 3.77Å; I387-M459 HydrophobicContact CB-SD 4.4Å; I387-M459 HydrophobicContact CG1-CG 4.49Å; I387-M459 HydrophobicContact CG1-SD 3.95Å
460D62.5Low86.1Confident11 Ų1110.8 Ų10.86%0.0596%0.059CC..SBendtrans-147.327.5-158.2-124.1-15000117.2R292 R296 Q336R292-D460 IonicContact CZ-OD1 2.73Å; R292-D460 IonicContact NE-OD1 3.15Å; R292-D460 PolarHBondContact NE-OD1 3Å; R292-D460 PolarHBondContact NH2-O 3.12Å; R292-D460 IonicContact NH2-OD1 2.68Å; R292-D460 PolarHBondContact NH2-OD1 3.48Å; R292-D460 IonicContact NH2-OD2 3.2Å; R296-D460 IonicContact CZ-OD1 2.78Å; R296-D460 IonicContact NH2-OD1 2.85Å; R296-D460 PolarHBondContact NH2-OD1 2.95Å; R296-D460 IonicContact NH2-OD2 3.96Å; Q336-D460 PolarHBondContact NE2-OD2 3.27Å; Q336-D460 PolarHBondContact OE1-OD2 3.28Å
461C58.5Low85.9Confident24 Ų2411.4 Ų11.416%0.1627%0.066CC..  trans-160.7137.9148.951.50000114.4C458 D463 R464C458-C461 PolarHBondContact SG-N 2.91Å; C461-D463 HydrophobicContact CB-CB 3.79Å; C461-D463 VanDerWaalsContact CB-OD2 3.25Å; C461-D463 WeakPolarHBondContact CB-OD2 3.47Å; C461-D463 PolarHBondContact O-N 2.88Å; C461-R464 PolarHBondContact O-N 3.45Å; C461-R464 PolarHBondContact SG-NE 3.31Å
462L66.9Low85.9Confident20 Ų207.6 Ų7.611%0.1055%0.048CC..Hα-helixtrans-56.3-38.4162.1-175.981.3000110.5R464 T465 N466 G509 I512L462-R464 PolarHBondContact O-N 2.84Å; L462-R464 VanDerWaalsContact O-N 3.12Å; L462-T465 PolarHBondContact O-N 2.88Å; L462-T465 PolarHBondContact O-OG1 3.39Å; L462-N466 WeakPolarHBondContact O-CB 3.29Å; L462-N466 PolarHBondContact O-N 2.98Å; L462-G509 WeakPolarHBondContact CD2-O 3.49Å; L462-I512 HydrophobicContact CD1-CB 4.35Å; L462-I512 HydrophobicContact CD1-CG2 3.73Å; L462-I512 HydrophobicContact CD2-CB 3.7Å; L462-I512 HydrophobicContact CD2-CG2 3.87Å; L462-I512 HydrophobicContact CG-CG2 4.47Å
463D71.9Confident86Confident11 Ų117.6 Ų7.66%0.0595%0.048CC..Hα-helixtrans-46.1-39.5179.3-40.2-40.2000112.7C461 A521 L522 R547C461-D463 HydrophobicContact CB-CB 3.79Å; C461-D463 VanDerWaalsContact CB-OD2 3.25Å; C461-D463 WeakPolarHBondContact CB-OD2 3.47Å; C461-D463 PolarHBondContact O-N 2.88Å; D463-A521 VanDerWaalsContact OD1-CA 3.31Å; D463-A521 WeakPolarHBondContact OD1-CA 3.31Å; D463-A521 WeakPolarHBondContact OD1-CB 3.49Å; D463-L522 WeakPolarHBondContact CB-O 3.47Å; D463-L522 VanDerWaalsContact CG-N 3.32Å; D463-L522 PolarHBondContact OD1-N 2.93Å; D463-L522 WeakPolarHBondContact OD2-CB 3.48Å; D463-R547 IonicContact OD1-NH2 2.85Å; D463-R547 PolarHBondContact OD1-NH2 3.2Å; D463-R547 IonicContact OD2-CZ 2.66Å; D463-R547 IonicContact OD2-NH1 2.71Å; D463-R547 PolarHBondContact OD2-NH1 3.3Å; D463-R547 IonicContact OD2-NH2 3.23Å
464R84.4Confident85.8Confident8 Ų811 Ų113%0.036%0.061CC..Hα-helixtrans-70.3-52.5172.5-96.2-176.9-79.3173-5.4112.4L377 E384 F410 H411 C458 C461 L462 N466 V467 V468L377-R464 HydrophobicContact CD1-CB 4.07Å; L377-R464 PolarHBondContact O-NH1 2.82Å; E384-R464 IonicContact OE1-CZ 2.82Å; E384-R464 IonicContact OE1-NH1 2.68Å; E384-R464 IonicContact OE1-NH2 2.69Å; E384-R464 PolarHBondContact OE1-NH2 2.98Å; E384-R464 IonicContact OE2-CZ 3.55Å; E384-R464 IonicContact OE2-NH1 3.35Å; E384-R464 PolarHBondContact OE2-NH1 2.88Å; E384-R464 IonicContact OE2-NH2 2.83Å; E384-R464 PolarHBondContact OE2-NH2 3.15Å; F410-R464 HydrophobicContact CB-CG 4.35Å; F410-R464 HydrophobicContact CD1-CG 3.5Å; F410-R464 HydrophobicContact CD2-CG 4.07Å; F410-R464 HydrophobicContact CE1-CG 3.69Å; F410-R464 HydrophobicContact CE2-CG 4.21Å; F410-R464 HydrophobicContact CG-CG 3.71Å; F410-R464 HydrophobicContact CZ-CG 4.04Å; H411-R464 PolarHBondContact CE1-NH1 3.27Å; H411-R464 VanDerWaalsContact CE1-NH1 3.26Å; C458-R464 HydrophobicContact CB-CB 4.45Å; C458-R464 PolarHBondContact SG-NE 2.85Å; C458-R464 PolarHBondContact SG-NH2 2.99Å; C461-R464 PolarHBondContact O-N 3.45Å; C461-R464 PolarHBondContact SG-NE 3.31Å; L462-R464 PolarHBondContact O-N 2.84Å; L462-R464 VanDerWaalsContact O-N 3.12Å; R464-N466 VanDerWaalsContact C-N 3.3Å; R464-N466 PolarHBondContact O-N 3.47Å; R464-V467 PolarHBondContact O-N 2.83Å; R464-V468 PolarHBondContact O-N 2.78Å
465T89.4Confident85.6Confident8 Ų812.1 Ų12.15%0.0497%0.067CC..Hα-helixtrans-63.3-34.8-175.665.80000112.9L377 V456 C458 L462 V468 Q469L377-T465 HydrophobicContact CD1-CG2 4.48Å; V456-T465 HydrophobicContact CG1-CG2 4.09Å; C458-T465 HydrophobicContact CB-CG2 3.44Å; C458-T465 VanDerWaalsContact CB-CG2 3.44Å; L462-T465 PolarHBondContact O-N 2.88Å; L462-T465 PolarHBondContact O-OG1 3.39Å; T465-V468 PolarHBondContact O-N 3.02Å; T465-Q469 WeakPolarHBondContact O-CB 3.43Å; T465-Q469 WeakPolarHBondContact O-CG 3.43Å; T465-Q469 PolarHBondContact O-N 2.83Å
466N91.2Very high85.6Confident4 Ų412.2 Ų12.22%0.0217%0.068CC..Hα-helixtrans-70.5-35.9-176.5-162.185.9000112.2R327 L462 R464 A470 W505 G509R327-N466 PolarHBondContact NH1-OD1 2.91Å; L462-N466 WeakPolarHBondContact O-CB 3.29Å; L462-N466 PolarHBondContact O-N 2.98Å; R464-N466 VanDerWaalsContact C-N 3.3Å; R464-N466 PolarHBondContact O-N 3.47Å; N466-A470 VanDerWaalsContact O-CB 3.22Å; N466-A470 WeakPolarHBondContact O-CB 3.34Å; N466-A470 PolarHBondContact O-N 3.42Å; N466-W505 PolarHBondContact ND2-O 3.27Å; N466-G509 WeakPolarHBondContact OD1-CA 3.32Å; N466-G509 PolarHBondContact OD1-N 3.27Å
467V87.3Confident85.6Confident15 Ų1512.2 Ų12.29%0.0917%0.068CC..Hα-helixtrans-64.8-46.4174.2169.40000110.8V422 R464 A470 A471 F526V422-V467 HydrophobicContact CG2-CG1 4.11Å; R464-V467 PolarHBondContact O-N 2.83Å; V467-A470 PolarHBondContact O-N 3.33Å; V467-A471 PolarHBondContact O-N 3.04Å; V467-F526 HydrophobicContact CG1-CE1 3.86Å; V467-F526 HydrophobicContact CG2-CD1 4.01Å; V467-F526 HydrophobicContact CG2-CE1 3.95Å
468V91.5Very high85.7Confident1 Ų113.7 Ų13.71%0.0068%0.075CC..Hα-helixtrans-69-42.1-179.7174.70000111.7I375 L377 F410 V422 L425 V456 R464 T465 A470 A471 I472I375-V468 HydrophobicContact CD1-CG1 4.41Å; I375-V468 HydrophobicContact CG2-CG1 4.36Å; L377-V468 HydrophobicContact CD1-CB 4.1Å; L377-V468 HydrophobicContact CD1-CG2 3.67Å; L377-V468 HydrophobicContact CD2-CG2 3.97Å; L377-V468 HydrophobicContact CG-CG2 4.48Å; F410-V468 HydrophobicContact CD2-CG2 4.38Å; F410-V468 HydrophobicContact CE2-CG2 4.18Å; V422-V468 HydrophobicContact CG1-CG2 4.2Å; L425-V468 HydrophobicContact CD2-CG1 3.9Å; L425-V468 HydrophobicContact CD2-CG2 4.32Å; V456-V468 HydrophobicContact CG1-CB 4.13Å; V456-V468 HydrophobicContact CG1-CG1 4.09Å; V456-V468 HydrophobicContact CG2-CG1 4.32Å; R464-V468 PolarHBondContact O-N 2.78Å; T465-V468 PolarHBondContact O-N 3.02Å; V468-A470 VanDerWaalsContact C-N 3.31Å; V468-A470 PolarHBondContact O-N 2.7Å; V468-A471 PolarHBondContact O-N 3.46Å; V468-I472 HydrophobicContact CG1-CD1 3.9Å; V468-I472 WeakPolarHBondContact O-CG1 3.41Å; V468-I472 PolarHBondContact O-N 3.35Å; V468-I472 VanDerWaalsContact O-N 3.08Å
469Q94.7Very high86.2Confident0 Ų015.1 Ų15.10%08%0.08CC..Hα-helixtrans-60.2-40.6173.1-75.9-170.4-28.600112.2T310 Q325 T326 R327 V456 T465 A473 W505T310-Q469 PolarHBondContact OG1-OE1 2.86Å; Q325-Q469 HydrophobicContact CB-CG 4.45Å; Q325-Q469 PolarHBondContact NE2-O 2.88Å; T326-Q469 VanDerWaalsContact C-NE2 3.32Å; T326-Q469 PolarHBondContact O-NE2 2.92Å; R327-Q469 VanDerWaalsContact CD-OE1 3.31Å; V456-Q469 HydrophobicContact CB-CG 4.08Å; V456-Q469 HydrophobicContact CG2-CG 3.67Å; T465-Q469 WeakPolarHBondContact O-CB 3.43Å; T465-Q469 WeakPolarHBondContact O-CG 3.43Å; T465-Q469 PolarHBondContact O-N 2.83Å; Q469-A473 WeakPolarHBondContact O-CB 3.2Å; Q469-A473 PolarHBondContact O-N 2.82Å; Q469-W505 HydrophobicContact CB-CH2 3.84Å; Q469-W505 HydrophobicContact CB-CZ3 3.64Å
470A94.1Very high87.2Confident11 Ų1115 Ų159%0.0918%0.079CC..Hα-helixtrans-67.5-33.5177.400000113.1N466 V467 V468 R474 Y501 W505N466-A470 VanDerWaalsContact O-CB 3.22Å; N466-A470 WeakPolarHBondContact O-CB 3.34Å; N466-A470 PolarHBondContact O-N 3.42Å; V467-A470 PolarHBondContact O-N 3.33Å; V468-A470 VanDerWaalsContact C-N 3.31Å; V468-A470 PolarHBondContact O-N 2.7Å; A470-R474 WeakPolarHBondContact O-CB 3.47Å; A470-R474 PolarHBondContact O-N 2.88Å; A470-R474 VanDerWaalsContact O-N 3.08Å; A470-Y501 PolarHBondContact O-OH 3.16Å; A470-W505 HydrophobicContact CB-CB 3.91Å; A470-W505 HydrophobicContact CB-CD2 3.52Å; A470-W505 HydrophobicContact CB-CE3 3.74Å; A470-W505 HydrophobicContact CB-CG 3.59Å; A470-W505 HydrophobicContact CB-CZ3 4.44Å
471A92.1Very high88.7Confident24 Ų2414.4 Ų14.420%0.1988%0.076CC..Hα-helixtrans-68.2-50.5175.400000111.4V422 T426 V467 V468 A473 R474 V475V422-A471 HydrophobicContact CG1-CB 3.78Å; T426-A471 HydrophobicContact CG2-CB 3.89Å; V467-A471 PolarHBondContact O-N 3.04Å; V468-A471 PolarHBondContact O-N 3.46Å; A471-A473 PolarHBondContact O-N 2.87Å; A471-R474 WeakPolarHBondContact O-CB 3.13Å; A471-R474 PolarHBondContact O-N 3.05Å; A471-R474 VanDerWaalsContact O-N 3.1Å; A471-V475 PolarHBondContact O-N 3.41Å
472I95.1Very high90.3Very high0 Ų015.9 Ų15.90%08%0.08CC..Hα-helixtrans-61-45.8178.4-63.2167.4000110.8F323 I375 T426 I429 I433 F454 V468 R474 V475 V476F323-I472 HydrophobicContact CE1-CG2 3.95Å; F323-I472 HydrophobicContact CZ-CG2 3.81Å; I375-I472 HydrophobicContact CD1-CD1 3.48Å; I375-I472 VanDerWaalsContact CD1-CD1 3.48Å; T426-I472 HydrophobicContact CG2-CG1 4.04Å; I429-I472 HydrophobicContact CD1-CD1 4.29Å; I433-I472 HydrophobicContact CD1-CG1 4.37Å; I433-I472 HydrophobicContact CD1-CG2 4.16Å; I433-I472 HydrophobicContact CG1-CG2 4.19Å; F454-I472 HydrophobicContact CB-CD1 4.34Å; F454-I472 HydrophobicContact CD1-CD1 4.37Å; F454-I472 HydrophobicContact CD2-CG2 3.72Å; F454-I472 HydrophobicContact CE2-CG2 3.92Å; F454-I472 HydrophobicContact CG-CD1 4.17Å; F454-I472 HydrophobicContact CG-CG2 4.33Å; V468-I472 HydrophobicContact CG1-CD1 3.9Å; V468-I472 WeakPolarHBondContact O-CG1 3.41Å; V468-I472 PolarHBondContact O-N 3.35Å; V468-I472 VanDerWaalsContact O-N 3.08Å; I472-R474 VanDerWaalsContact C-N 3.26Å; I472-R474 PolarHBondContact O-N 2.67Å; I472-V475 PolarHBondContact O-N 3Å; I472-V476 PolarHBondContact O-N 3.34Å; I472-V476 VanDerWaalsContact O-N 3.13Å
473A95.9Very high91.5Very high0 Ų021 Ų210%010%0.101CC..Hα-helixtrans-59.3-34.5175.200000112.8Q312 F323 Q469 A471 V476 M477 Y501 W505Q312-A473 PolarHBondContact OE1-O 2.8Å; F323-A473 HydrophobicContact CD1-CB 4.41Å; F323-A473 HydrophobicContact CE1-CB 4.45Å; Q469-A473 WeakPolarHBondContact O-CB 3.2Å; Q469-A473 PolarHBondContact O-N 2.82Å; A471-A473 PolarHBondContact O-N 2.87Å; A473-V476 PolarHBondContact O-N 3.4Å; A473-M477 VanDerWaalsContact O-CB 3.3Å; A473-M477 WeakPolarHBondContact O-CB 3.46Å; A473-M477 PolarHBondContact O-N 3.02Å; A473-Y501 WeakPolarHBondContact CB-OH 3.39Å; A473-W505 HydrophobicContact CB-CH2 4.22Å; A473-W505 HydrophobicContact CB-CZ2 3.45Å; A473-W505 VanDerWaalsContact CB-CZ2 3.45Å
474R93.1Very high92.4Very high77 Ų7722 Ų2229%0.29111%0.106SC..Hα-helixtrans-67.9-45.1178-175.4177.2165.4-163-15111.1A470 A471 I472 V476 M477 E478 N498 Y501A470-R474 WeakPolarHBondContact O-CB 3.47Å; A470-R474 PolarHBondContact O-N 2.88Å; A470-R474 VanDerWaalsContact O-N 3.08Å; A471-R474 WeakPolarHBondContact O-CB 3.13Å; A471-R474 PolarHBondContact O-N 3.05Å; A471-R474 VanDerWaalsContact O-N 3.1Å; I472-R474 VanDerWaalsContact C-N 3.26Å; I472-R474 PolarHBondContact O-N 2.67Å; R474-V476 VanDerWaalsContact C-N 3.31Å; R474-V476 PolarHBondContact O-N 3.21Å; R474-M477 PolarHBondContact O-N 2.99Å; R474-E478 HydrophobicContact CG-CG 4.39Å; R474-E478 IonicContact CZ-OE1 2.75Å; R474-E478 IonicContact NE-OE1 2.81Å; R474-E478 PolarHBondContact NE-OE1 3.08Å; R474-E478 IonicContact NH2-OE1 3.24Å; R474-E478 PolarHBondContact NH2-OE1 2.81Å; R474-E478 WeakPolarHBondContact O-CG 3.15Å; R474-E478 PolarHBondContact O-N 2.99Å; R474-N498 PolarHBondContact NH1-OD1 2.99Å; R474-Y501 HydrophobicContact CB-CE1 3.8Å; R474-Y501 HydrophobicContact CG-CE1 4.25Å; R474-Y501 PolarHBondContact N-OH 3.41Å
475V92.3Very high92.7Very high22 Ų2224.7 Ų24.713%0.13314%0.137CC..Hα-helixtrans-58.1-45.1176.6176.70000110.7Y430 I433 A471 I472 Q479Y430-V475 HydrophobicContact CD2-CG1 3.97Å; Y430-V475 HydrophobicContact CE2-CG1 3.75Å; I433-V475 HydrophobicContact CD1-CG1 4.43Å; I433-V475 HydrophobicContact CG2-CG1 4.11Å; A471-V475 PolarHBondContact O-N 3.41Å; I472-V475 PolarHBondContact O-N 3Å; V475-Q479 WeakPolarHBondContact O-CG 3.44Å; V475-Q479 PolarHBondContact O-N 2.91Å
476V95.6Very high92.7Very high2 Ų224.8 Ų24.81%0.01214%0.138CC..Hα-helixtrans-65.3-45.5176.7177.10000111.6F323 I433 W438 I472 A473 R474 E478 Q479 Q480F323-V476 HydrophobicContact CB-CG1 3.9Å; F323-V476 HydrophobicContact CD1-CB 3.99Å; F323-V476 HydrophobicContact CD1-CG1 4.08Å; F323-V476 HydrophobicContact CD1-CG2 4.07Å; F323-V476 HydrophobicContact CD2-CB 4.48Å; F323-V476 HydrophobicContact CD2-CG1 4Å; F323-V476 HydrophobicContact CD2-CG2 4.16Å; F323-V476 HydrophobicContact CE1-CB 4.19Å; F323-V476 HydrophobicContact CE1-CG2 3.8Å; F323-V476 HydrophobicContact CE2-CG2 3.92Å; F323-V476 HydrophobicContact CG-CB 4.15Å; F323-V476 HydrophobicContact CG-CG1 3.73Å; F323-V476 HydrophobicContact CG-CG2 4.24Å; F323-V476 HydrophobicContact CZ-CG2 3.73Å; I433-V476 HydrophobicContact CG2-CG2 3.47Å; I433-V476 VanDerWaalsContact CG2-CG2 3.47Å; W438-V476 HydrophobicContact CB-CG1 4.31Å; W438-V476 HydrophobicContact CD2-CG1 4.32Å; W438-V476 HydrophobicContact CE3-CG1 3.9Å; I472-V476 PolarHBondContact O-N 3.34Å; I472-V476 VanDerWaalsContact O-N 3.13Å; A473-V476 PolarHBondContact O-N 3.4Å; R474-V476 VanDerWaalsContact C-N 3.31Å; R474-V476 PolarHBondContact O-N 3.21Å; V476-E478 PolarHBondContact O-N 3.09Å; V476-Q479 WeakPolarHBondContact O-CB 3.4Å; V476-Q479 PolarHBondContact O-N 2.62Å; V476-Q479 VanDerWaalsContact O-N 3.16Å; V476-Q480 HydrophobicContact CG1-CG 4.12Å; V476-Q480 VanDerWaalsContact O-CG 3.27Å; V476-Q480 WeakPolarHBondContact O-CG 3.3Å; V476-Q480 PolarHBondContact O-N 2.97Å
477M94.4Very high92.6Very high0 Ų024.8 Ų24.80%014%0.138CC..Hα-helixtrans-60-43.9178.4-175.3179.365.500112.7F276 Q312 I314 A473 R474 Q479 Q480 L481 L493 Y501F276-M477 HydrophobicContact CE2-SD 4.38Å; Q312-M477 PolarHBondContact NE2-SD 2.85Å; I314-M477 HydrophobicContact CD1-CG 3.69Å; I314-M477 HydrophobicContact CD1-SD 3.74Å; I314-M477 HydrophobicContact CG1-CG 4.07Å; A473-M477 VanDerWaalsContact O-CB 3.3Å; A473-M477 WeakPolarHBondContact O-CB 3.46Å; A473-M477 PolarHBondContact O-N 3.02Å; R474-M477 PolarHBondContact O-N 2.99Å; M477-Q479 VanDerWaalsContact C-N 3.28Å; M477-Q479 PolarHBondContact O-N 3.03Å; M477-Q480 WeakPolarHBondContact O-CB 3.19Å; M477-Q480 PolarHBondContact O-N 2.99Å; M477-L481 HydrophobicContact CG-CD1 3.95Å; M477-L481 HydrophobicContact CG-CG 4.35Å; M477-L481 VanDerWaalsContact O-CG 3.31Å; M477-L481 WeakPolarHBondContact O-CG 3.31Å; M477-L481 PolarHBondContact O-N 3.45Å; M477-L493 HydrophobicContact CE-CD1 4.2Å; M477-L493 HydrophobicContact CE-CD2 3.45Å; M477-L493 VanDerWaalsContact CE-CD2 3.45Å; M477-L493 HydrophobicContact CE-CG 4.47Å; M477-Y501 HydrophobicContact CE-CD2 3.55Å; M477-Y501 HydrophobicContact CE-CE2 3.79Å; M477-Y501 HydrophobicContact CE-CG 4.01Å; M477-Y501 HydrophobicContact SD-CD2 3.85Å; M477-Y501 HydrophobicContact SD-CE2 3.99Å
478E92.4Very high92.5Very high31 Ų3126.6 Ų26.615%0.14515%0.149CC..Hα-helixtrans-64-34.8177.5-71.1-174-17600111.5R474 V476 K482 M487 L493R474-E478 HydrophobicContact CG-CG 4.39Å; R474-E478 IonicContact CZ-OE1 2.75Å; R474-E478 IonicContact NE-OE1 2.81Å; R474-E478 PolarHBondContact NE-OE1 3.08Å; R474-E478 IonicContact NH2-OE1 3.24Å; R474-E478 PolarHBondContact NH2-OE1 2.81Å; R474-E478 WeakPolarHBondContact O-CG 3.15Å; R474-E478 PolarHBondContact O-N 2.99Å; V476-E478 PolarHBondContact O-N 3.09Å; E478-K482 WeakPolarHBondContact O-CB 3.49Å; E478-K482 WeakPolarHBondContact O-CD 3.44Å; E478-K482 WeakPolarHBondContact O-CG 3.08Å; E478-K482 PolarHBondContact O-N 3.43Å; E478-K482 VanDerWaalsContact O-N 3.15Å; E478-M487 HydrophobicContact CB-CE 3.81Å; E478-M487 HydrophobicContact CG-CE 3.93Å; E478-L493 HydrophobicContact CG-CB 4.17Å; E478-L493 WeakPolarHBondContact OE1-CB 3.42Å
479Q92.5Very high92.1Very high45 Ų4531.6 Ų31.621%0.2118%0.182CC..Hα-helixtrans-71-37.5172-70.8-66.5-12.900113.3Y430 L434 W438 V475 V476 M477 K483Y430-Q479 PolarHBondContact OH-NE2 3.44Å; L434-Q479 HydrophobicContact CD2-CG 4.2Å; W438-Q479 HydrophobicContact CH2-CB 3.82Å; W438-Q479 HydrophobicContact CZ3-CB 4.1Å; V475-Q479 WeakPolarHBondContact O-CG 3.44Å; V475-Q479 PolarHBondContact O-N 2.91Å; V476-Q479 WeakPolarHBondContact O-CB 3.4Å; V476-Q479 PolarHBondContact O-N 2.62Å; V476-Q479 VanDerWaalsContact O-N 3.16Å; M477-Q479 VanDerWaalsContact C-N 3.28Å; M477-Q479 PolarHBondContact O-N 3.03Å; Q479-K483 PolarHBondContact O-N 3.13Å
480Q94.9Very high91.5Very high0 Ų040.7 Ų40.70%023%0.225CC..Hα-helixtrans-62.4-49175.1-73.5175.9-22.200111.4L321 W438 V476 M477 K482 K483 L484L321-Q480 HydrophobicContact CD2-CB 3.82Å; L321-Q480 HydrophobicContact CD2-CG 3.81Å; W438-Q480 HydrophobicContact CD2-CG 3.84Å; W438-Q480 HydrophobicContact CE3-CG 4.43Å; W438-Q480 HydrophobicContact CG-CG 4.05Å; W438-Q480 VanDerWaalsContact CG-NE2 3.32Å; W438-Q480 HydrophobicContact CH2-CG 4.48Å; W438-Q480 HydrophobicContact CZ2-CG 3.91Å; V476-Q480 HydrophobicContact CG1-CG 4.12Å; V476-Q480 VanDerWaalsContact O-CG 3.27Å; V476-Q480 WeakPolarHBondContact O-CG 3.3Å; V476-Q480 PolarHBondContact O-N 2.97Å; M477-Q480 WeakPolarHBondContact O-CB 3.19Å; M477-Q480 PolarHBondContact O-N 2.99Å; Q480-K482 VanDerWaalsContact C-N 3.34Å; Q480-K482 PolarHBondContact O-N 3.47Å; Q480-K483 PolarHBondContact O-N 3.28Å; Q480-L484 WeakPolarHBondContact O-CG 3.39Å; Q480-L484 PolarHBondContact O-N 3.17Å
481L93.7Very high90.9Very high0 Ų044 Ų440%024%0.238CC..Hα-helixtrans-66.1-34.4179.7-64170.1000112.4F276 I314 M477 L484 G485 V486 M487 L493F276-L481 HydrophobicContact CB-CD2 4.25Å; F276-L481 HydrophobicContact CD1-CD2 3.85Å; F276-L481 HydrophobicContact CD2-CD2 3.82Å; F276-L481 HydrophobicContact CE1-CD1 3.95Å; F276-L481 HydrophobicContact CE1-CD2 4.04Å; F276-L481 HydrophobicContact CE2-CD1 4.04Å; F276-L481 HydrophobicContact CE2-CD2 3.99Å; F276-L481 HydrophobicContact CG-CD2 3.73Å; F276-L481 HydrophobicContact CZ-CD1 3.62Å; F276-L481 HydrophobicContact CZ-CD2 4.09Å; I314-L481 HydrophobicContact CG2-CD2 3.88Å; M477-L481 HydrophobicContact CG-CD1 3.95Å; M477-L481 HydrophobicContact CG-CG 4.35Å; M477-L481 VanDerWaalsContact O-CG 3.31Å; M477-L481 WeakPolarHBondContact O-CG 3.31Å; M477-L481 PolarHBondContact O-N 3.45Å; L481-L484 PolarHBondContact O-N 3.08Å; L481-G485 PolarHBondContact O-N 3.25Å; L481-V486 HydrophobicContact CD2-CB 4.31Å; L481-V486 HydrophobicContact CD2-CG1 3.87Å; L481-V486 PolarHBondContact O-N 3.26Å; L481-M487 HydrophobicContact CB-CB 3.83Å; L481-M487 HydrophobicContact CD1-SD 4.45Å; L481-M487 PolarHBondContact O-N 2.87Å; L481-L493 HydrophobicContact CD1-CD1 3.88Å
482K92.4Very high90.6Very high55 Ų5546.6 Ų46.624%0.23925%0.253CS..Hα-helixtrans-65-45.5172-75.3172.6-171.4-166.60112.2E478 Q480 L484 G485 M487 P488 P489 Q491E478-K482 WeakPolarHBondContact O-CB 3.49Å; E478-K482 WeakPolarHBondContact O-CD 3.44Å; E478-K482 WeakPolarHBondContact O-CG 3.08Å; E478-K482 PolarHBondContact O-N 3.43Å; E478-K482 VanDerWaalsContact O-N 3.15Å; Q480-K482 VanDerWaalsContact C-N 3.34Å; Q480-K482 PolarHBondContact O-N 3.47Å; K482-L484 VanDerWaalsContact C-N 3.28Å; K482-L484 PolarHBondContact O-N 2.91Å; K482-G485 PolarHBondContact O-N 3.33Å; K482-G485 VanDerWaalsContact O-N 3.14Å; K482-M487 HydrophobicContact CD-CE 4.23Å; K482-M487 HydrophobicContact CG-CB 4.37Å; K482-M487 HydrophobicContact CG-CE 4.02Å; K482-P488 WeakPolarHBondContact CE-O 3.38Å; K482-P489 VanDerWaalsContact CE-O 3.31Å; K482-P489 WeakPolarHBondContact CE-O 3.42Å; K482-P489 PolarHBondContact NZ-O 3.19Å; K482-Q491 WeakPolarHBondContact CE-O 3.39Å; K482-Q491 PolarHBondContact NZ-O 2.94Å
483K91.9Very high90.1Very high127 Ų12747 Ų4755%0.55226%0.255SS*.Hα-helixtrans-67.9-25176.8-70.2-162.5-164.5165.50113.9W438 Q479 Q480 G485W438-K483 HydrophobicContact CH2-CD 4.06Å; W438-K483 HydrophobicContact CZ2-CD 3.77Å; W438-K483 HydrophobicContact CZ2-CG 4.41Å; Q479-K483 PolarHBondContact O-N 3.13Å; Q480-K483 PolarHBondContact O-N 3.28Å; K483-G485 VanDerWaalsContact C-N 3.3Å
484L92.3Very high89.7Confident31 Ų3147.3 Ų47.316%0.16226%0.257CS..THydrogen-bonded Turntrans-82-2.6173.6-73.3167.7000113.9I314 V316 H319 L321 W440 Q480 L481 K482 V486I314-L484 HydrophobicContact CG2-CD1 4.35Å; V316-L484 HydrophobicContact CB-CD1 4.12Å; V316-L484 HydrophobicContact CG2-CD1 3.9Å; H319-L484 HydrophobicContact CB-CD2 3.97Å; L321-L484 HydrophobicContact CD1-CD1 3.89Å; L321-L484 HydrophobicContact CD1-CD2 4.17Å; L321-L484 HydrophobicContact CD1-CG 4.42Å; L321-L484 HydrophobicContact CD2-CD1 3.89Å; L321-L484 HydrophobicContact CD2-CG 4.24Å; W440-L484 HydrophobicContact CZ2-CD2 3.88Å; Q480-L484 WeakPolarHBondContact O-CG 3.39Å; Q480-L484 PolarHBondContact O-N 3.17Å; L481-L484 PolarHBondContact O-N 3.08Å; K482-L484 VanDerWaalsContact C-N 3.28Å; K482-L484 PolarHBondContact O-N 2.91Å; L484-V486 HydrophobicContact CB-CG2 4.17Å; L484-V486 PolarHBondContact O-N 3.1Å; L484-V486 VanDerWaalsContact O-N 3.16Å
485G89.7Confident89.4Confident66 Ų6649 Ų4968%0.6828%0.276SS*.THydrogen-bonded Turntrans68.95.1-175.100000114.7L481 K482 K483 M487L481-G485 PolarHBondContact O-N 3.25Å; K482-G485 PolarHBondContact O-N 3.33Å; K482-G485 VanDerWaalsContact O-N 3.14Å; K483-G485 VanDerWaalsContact C-N 3.3Å; G485-M487 VanDerWaalsContact C-N 3.33Å
486V89.5Confident89.2Confident10 Ų1051.7 Ų51.76%0.06129%0.286CS..SBendtrans-76.3-22.4179.3166.50000111.9V246 P274 F276 V316 L481 L484V246-V486 HydrophobicContact CG2-CG1 3.75Å; P274-V486 HydrophobicContact CB-CG1 4.25Å; P274-V486 HydrophobicContact CB-CG2 4.43Å; F276-V486 HydrophobicContact CD1-CG1 4.08Å; V316-V486 HydrophobicContact CG1-CG2 3.77Å; V316-V486 HydrophobicContact CG2-CG2 4.05Å; L481-V486 HydrophobicContact CD2-CB 4.31Å; L481-V486 HydrophobicContact CD2-CG1 3.87Å; L481-V486 PolarHBondContact O-N 3.26Å; L484-V486 HydrophobicContact CB-CG2 4.17Å; L484-V486 PolarHBondContact O-N 3.1Å; L484-V486 VanDerWaalsContact O-N 3.16Å
487M88.8Confident88.9Confident4 Ų451.7 Ų51.72%0.0229%0.286CS..SBendtrans-132.7134-179.9-157.2171.679.400111.4Y248 E478 L481 K482 G485 L493Y248-M487 WeakPolarHBondContact OH-CG 3.48Å; E478-M487 HydrophobicContact CB-CE 3.81Å; E478-M487 HydrophobicContact CG-CE 3.93Å; L481-M487 HydrophobicContact CB-CB 3.83Å; L481-M487 HydrophobicContact CD1-SD 4.45Å; L481-M487 PolarHBondContact O-N 2.87Å; K482-M487 HydrophobicContact CD-CE 4.23Å; K482-M487 HydrophobicContact CG-CB 4.37Å; K482-M487 HydrophobicContact CG-CE 4.02Å; G485-M487 VanDerWaalsContact C-N 3.33Å; M487-L493 HydrophobicContact SD-CB 4.33Å; M487-L493 HydrophobicContact SD-CD1 4.08Å
488P85.7Confident88.7Confident52 Ų5253 Ų5334%0.33829%0.293SS..  trans-60.9147.1178.6-25.435.9000113Y248 K482 E490 Q491Y248-P488 HydrophobicContact CE2-CG 4.33Å; K482-P488 WeakPolarHBondContact CE-O 3.38Å; P488-E490 VanDerWaalsContact C-N 3.29Å; P488-E490 PolarHBondContact O-N 2.92Å; P488-Q491 HydrophobicContact CB-CB 4.17Å; P488-Q491 HydrophobicContact CB-CG 4.11Å; P488-Q491 HydrophobicContact CG-CB 4.44Å; P488-Q491 HydrophobicContact CG-CG 4.43Å; P488-Q491 PolarHBondContact O-N 2.84Å
489P83.4Confident88.5Confident107 Ų10759.1 Ų59.170%0.69532%0.315SS*.THydrogen-bonded Turntrans-58.7-35.5-176.5-27.535.8000114.9K482K482-P489 VanDerWaalsContact CE-O 3.31Å; K482-P489 WeakPolarHBondContact CE-O 3.42Å; K482-P489 PolarHBondContact NZ-O 3.19Å
490E81.3Confident88.4Confident190 Ų19059.7 Ų59.789%0.88832%0.319SS*.THydrogen-bonded Turntrans-93.2-15.6-174-62.5-179.617400113.7P488P488-E490 VanDerWaalsContact C-N 3.29Å; P488-E490 PolarHBondContact O-N 2.92Å
491Q82.4Confident88.3Confident81 Ų8160 Ų6038%0.37932%0.32SS..PPolyproline II helixtrans-91.6146.2-175.1-65.1-176.2-100111.8Y248 K482 P488Y248-Q491 HydrophobicContact CE1-CB 3.94Å; Y248-Q491 VanDerWaalsContact CE2-OE1 3.29Å; Y248-Q491 VanDerWaalsContact CZ-OE1 3.3Å; K482-Q491 WeakPolarHBondContact CE-O 3.39Å; K482-Q491 PolarHBondContact NZ-O 2.94Å; P488-Q491 HydrophobicContact CB-CB 4.17Å; P488-Q491 HydrophobicContact CB-CG 4.11Å; P488-Q491 HydrophobicContact CG-CB 4.44Å; P488-Q491 HydrophobicContact CG-CG 4.43Å; P488-Q491 PolarHBondContact O-N 2.84Å
492P84.6Confident88.1Confident79 Ų7962.1 Ų62.151%0.51333%0.33SS..PPolyproline II helixtrans-77.4171.1170.534.2-35.9000110.8Y248Y248-P492 VanDerWaalsContact CE1-O 3.26Å; Y248-P492 WeakPolarHBondContact CE1-O 3.31Å; Y248-P492 PolarHBondContact OH-O 3.15Å
493L85.2Confident88.1Confident8 Ų862.4 Ų62.44%0.04233%0.333CS..PPolyproline II helixtrans-58.3133.7171.4-172.272.4000111.6F276 M477 E478 L481 M487 C497 N498F276-L493 HydrophobicContact CZ-CD1 4.45Å; M477-L493 HydrophobicContact CE-CD1 4.2Å; M477-L493 HydrophobicContact CE-CD2 3.45Å; M477-L493 VanDerWaalsContact CE-CD2 3.45Å; M477-L493 HydrophobicContact CE-CG 4.47Å; E478-L493 HydrophobicContact CG-CB 4.17Å; E478-L493 WeakPolarHBondContact OE1-CB 3.42Å; L481-L493 HydrophobicContact CD1-CD1 3.88Å; M487-L493 HydrophobicContact SD-CB 4.33Å; M487-L493 HydrophobicContact SD-CD1 4.08Å; L493-C497 HydrophobicContact CD1-CB 3.91Å; L493-C497 HydrophobicContact CD2-CB 4.25Å; L493-C497 HydrophobicContact CG-CB 3.85Å; L493-N498 HydrophobicContact CD2-CB 3.96Å; L493-N498 HydrophobicContact CG-CB 4.44Å
494P88.5Confident88.2Confident7 Ų756.4 Ų56.45%0.04531%0.307CS..PPolyproline II helixtrans-55.6147.7178.7-27.534.3000113.8V246 N247 Y248 K496 C497 N498V246-P494 HydrophobicContact CG1-CG 3.91Å; N247-P494 WeakPolarHBondContact O-CB 3.49Å; Y248-P494 HydrophobicContact CD1-CG 4.16Å; Y248-P494 HydrophobicContact CD2-CG 4.41Å; Y248-P494 HydrophobicContact CE1-CB 4.47Å; Y248-P494 HydrophobicContact CE1-CG 3.75Å; Y248-P494 HydrophobicContact CE2-CG 4.02Å; Y248-P494 HydrophobicContact CG-CG 4.49Å; P494-K496 VanDerWaalsContact C-N 3.31Å; P494-K496 PolarHBondContact O-N 2.93Å; P494-C497 HydrophobicContact CB-CB 4.37Å; P494-C497 WeakPolarHBondContact O-CB 3.21Å; P494-C497 PolarHBondContact O-N 2.78Å; P494-C497 VanDerWaalsContact O-N 3.08Å; P494-N498 PolarHBondContact O-N 3.48Å
495V86.6Confident88.3Confident112 Ų11255.1 Ų55.168%0.67930%0.3SS*.Hα-helixtrans-57.2-41.6-174-177.70000112.3N498 R499V495-N498 PolarHBondContact O-N 2.93Å; V495-R499 WeakPolarHBondContact O-CB 3.17Å; V495-R499 PolarHBondContact O-N 3.17Å
496K87.3Confident88.4Confident78 Ų7852.1 Ų52.134%0.33927%0.269SS..Hα-helixtrans-64.3-45.8177-64-170.7-179.5-1710111.7E250 D253 P494 R499 I500E250-K496 IonicContact OE1-NZ 3.93Å; E250-K496 PolarHBondContact OE1-NZ 3.14Å; E250-K496 WeakPolarHBondContact OE2-CD 3.38Å; E250-K496 VanDerWaalsContact OE2-CE 3.29Å; E250-K496 WeakPolarHBondContact OE2-CE 3.4Å; E250-K496 IonicContact OE2-NZ 3.39Å; E250-K496 PolarHBondContact OE2-NZ 3.02Å; D253-K496 IonicContact OD2-NZ 2.77Å; D253-K496 PolarHBondContact OD2-NZ 3.37Å; P494-K496 VanDerWaalsContact C-N 3.31Å; P494-K496 PolarHBondContact O-N 2.93Å; K496-R499 PolarHBondContact O-N 3.45Å; K496-I500 WeakPolarHBondContact O-CG1 3.39Å; K496-I500 PolarHBondContact O-N 2.87Å; K496-I500 VanDerWaalsContact O-N 3.1Å
497C90.1Very high88.5Confident2 Ų253.7 Ų53.71%0.01428%0.277CS..Hα-helixtrans-61.4-46.6174.9-66.20000112.4L244 V245 L493 P494 R499 I500 Y501L244-C497 HydrophobicContact CD1-CB 4.25Å; V245-C497 PolarHBondContact O-SG 3.49Å; L493-C497 HydrophobicContact CD1-CB 3.91Å; L493-C497 HydrophobicContact CD2-CB 4.25Å; L493-C497 HydrophobicContact CG-CB 3.85Å; P494-C497 HydrophobicContact CB-CB 4.37Å; P494-C497 WeakPolarHBondContact O-CB 3.21Å; P494-C497 PolarHBondContact O-N 2.78Å; P494-C497 VanDerWaalsContact O-N 3.08Å; C497-R499 VanDerWaalsContact C-N 3.31Å; C497-R499 PolarHBondContact O-N 2.87Å; C497-I500 PolarHBondContact O-N 2.81Å; C497-Y501 WeakPolarHBondContact O-CB 3.5Å; C497-Y501 PolarHBondContact O-N 3.01Å
498N89.1Confident88.8Confident28 Ų2853.5 Ų53.515%0.1528%0.276CS..Hα-helixtrans-61-38.8177.1179.856.4000112.1R474 L493 P494 V495 Y501 Q502R474-N498 PolarHBondContact NH1-OD1 2.99Å; L493-N498 HydrophobicContact CD2-CB 3.96Å; L493-N498 HydrophobicContact CG-CB 4.44Å; P494-N498 PolarHBondContact O-N 3.48Å; V495-N498 PolarHBondContact O-N 2.93Å; N498-Y501 PolarHBondContact O-N 3.37Å; N498-Q502 PolarHBondContact ND2-NE2 3.2Å; N498-Q502 WeakPolarHBondContact O-CB 3.45Å; N498-Q502 VanDerWaalsContact O-CG 3.25Å; N498-Q502 WeakPolarHBondContact O-CG 3.43Å; N498-Q502 PolarHBondContact O-N 2.89Å
499R88.2Confident89Confident160 Ų16051.1 Ų51.160%0.60426%0.261SS*.Hα-helixtrans-66.8-39.8177.3-173.9171.6177.7166.5-3.3112.5V495 K496 C497 I503V495-R499 WeakPolarHBondContact O-CB 3.17Å; V495-R499 PolarHBondContact O-N 3.17Å; K496-R499 PolarHBondContact O-N 3.45Å; C497-R499 VanDerWaalsContact C-N 3.31Å; C497-R499 PolarHBondContact O-N 2.87Å; R499-I503 HydrophobicContact CG-CD1 4.31Å; R499-I503 WeakPolarHBondContact O-CD1 3.49Å; R499-I503 VanDerWaalsContact O-CG1 3.29Å; R499-I503 WeakPolarHBondContact O-CG1 3.37Å; R499-I503 PolarHBondContact O-N 2.86Å; R499-I503 VanDerWaalsContact O-N 3.08Å
500I91.6Very high89.3Confident57 Ų5746.8 Ų46.829%0.29223%0.232SC..Hα-helixtrans-68.1-45.1175.1-64164.8000110.1E242 L244 K496 C497 Q502 I503 M504E242-I500 HydrophobicContact CB-CG2 4.13Å; E242-I500 HydrophobicContact CG-CG2 3.88Å; L244-I500 HydrophobicContact CD2-CB 3.82Å; L244-I500 HydrophobicContact CD2-CD1 3.47Å; L244-I500 VanDerWaalsContact CD2-CD1 3.47Å; L244-I500 HydrophobicContact CD2-CG1 4.24Å; L244-I500 HydrophobicContact CD2-CG2 3.78Å; K496-I500 WeakPolarHBondContact O-CG1 3.39Å; K496-I500 PolarHBondContact O-N 2.87Å; K496-I500 VanDerWaalsContact O-N 3.1Å; C497-I500 PolarHBondContact O-N 2.81Å; I500-Q502 VanDerWaalsContact C-N 3.35Å; I500-Q502 PolarHBondContact O-N 3.31Å; I500-I503 WeakPolarHBondContact O-CA 3.45Å; I500-I503 WeakPolarHBondContact O-CB 3.36Å; I500-I503 PolarHBondContact O-N 2.86Å; I500-M504 HydrophobicContact CG2-CG 4.42Å; I500-M504 HydrophobicContact CG2-SD 4.42Å; I500-M504 WeakPolarHBondContact O-CG 3.27Å; I500-M504 PolarHBondContact O-N 3.34Å
501Y92.3Very high89.8Confident7 Ų738.1 Ų38.13%0.02719%0.192CC..Hα-helixtrans-54.8-46.4174.2177.3-94.8000112.8A470 A473 R474 M477 C497 N498 I503 M504 W505A470-Y501 PolarHBondContact O-OH 3.16Å; A473-Y501 WeakPolarHBondContact CB-OH 3.39Å; R474-Y501 HydrophobicContact CB-CE1 3.8Å; R474-Y501 HydrophobicContact CG-CE1 4.25Å; R474-Y501 PolarHBondContact N-OH 3.41Å; M477-Y501 HydrophobicContact CE-CD2 3.55Å; M477-Y501 HydrophobicContact CE-CE2 3.79Å; M477-Y501 HydrophobicContact CE-CG 4.01Å; M477-Y501 HydrophobicContact SD-CD2 3.85Å; M477-Y501 HydrophobicContact SD-CE2 3.99Å; C497-Y501 WeakPolarHBondContact O-CB 3.5Å; C497-Y501 PolarHBondContact O-N 3.01Å; N498-Y501 PolarHBondContact O-N 3.37Å; Y501-I503 VanDerWaalsContact C-N 3.35Å; Y501-I503 PolarHBondContact O-N 3.17Å; Y501-M504 PolarHBondContact O-N 2.78Å; Y501-W505 AromaticContact CD2-CD1 3.97Å; Y501-W505 AromaticContact CE1-CD1 3.69Å; Y501-W505 AromaticContact CE1-NE1 3.98Å; Y501-W505 AromaticContact CE2-CD1 3.52Å; Y501-W505 AromaticContact CE2-NE1 3.23Å; Y501-W505 AromaticContact CZ-CD1 3.35Å; Y501-W505 AromaticContact CZ-NE1 3.16Å; Y501-W505 PolarHBondContact O-N 3.34Å; Y501-W505 PolarHBondContact OH-NE1 2.81Å
502Q90.1Very high90.2Very high44 Ų4434.5 Ų34.521%0.20618%0.175CC..Hα-helixtrans-58.2-43173.2-81.4176.7-12.400112.2N498 I500 A506 T527 R528N498-Q502 PolarHBondContact ND2-NE2 3.2Å; N498-Q502 WeakPolarHBondContact O-CB 3.45Å; N498-Q502 VanDerWaalsContact O-CG 3.25Å; N498-Q502 WeakPolarHBondContact O-CG 3.43Å; N498-Q502 PolarHBondContact O-N 2.89Å; I500-Q502 VanDerWaalsContact C-N 3.35Å; I500-Q502 PolarHBondContact O-N 3.31Å; Q502-A506 WeakPolarHBondContact O-CB 3.43Å; Q502-A506 PolarHBondContact O-N 3.17Å; Q502-T527 CarbonylContact C-O 3.58Å; Q502-T527 WeakPolarHBondContact CA-O 3.31Å; Q502-T527 VanDerWaalsContact CB-O 3.24Å; Q502-T527 WeakPolarHBondContact CB-O 3.31Å; Q502-T527 VanDerWaalsContact O-O 3.1Å; Q502-R528 PolarHBondContact OE1-O 3.4Å
503I92Very high90.4Very high61 Ų6130.8 Ų30.831%0.31315%0.152SC..Hα-helixtrans-64.8-44.7176-70.6162.9000111.6R499 I500 Y501 W505 A506 N507R499-I503 HydrophobicContact CG-CD1 4.31Å; R499-I503 WeakPolarHBondContact O-CD1 3.49Å; R499-I503 VanDerWaalsContact O-CG1 3.29Å; R499-I503 WeakPolarHBondContact O-CG1 3.37Å; R499-I503 PolarHBondContact O-N 2.86Å; R499-I503 VanDerWaalsContact O-N 3.08Å; I500-I503 WeakPolarHBondContact O-CA 3.45Å; I500-I503 WeakPolarHBondContact O-CB 3.36Å; I500-I503 PolarHBondContact O-N 2.86Å; Y501-I503 VanDerWaalsContact C-N 3.35Å; Y501-I503 PolarHBondContact O-N 3.17Å; I503-W505 PolarHBondContact O-N 3.15Å; I503-A506 PolarHBondContact O-N 2.95Å; I503-N507 WeakPolarHBondContact O-CB 3.44Å; I503-N507 PolarHBondContact O-N 3.29Å; I503-N507 PolarHBondContact O-ND2 3Å
504M94.7Very high90.5Very high1 Ų133.3 Ų33.31%0.00516%0.161CC..Hα-helixtrans-58.8-48177-66.7176.183.700111.7Q240 E242 V278 L280 I500 Y501 A506 N507 N508Q240-M504 HydrophobicContact CB-CE 4.39Å; Q240-M504 HydrophobicContact CG-CE 4.29Å; Q240-M504 HydrophobicContact CG-CG 4.3Å; Q240-M504 WeakPolarHBondContact O-CE 3.5Å; E242-M504 HydrophobicContact CB-CE 4.24Å; E242-M504 HydrophobicContact CB-SD 3.99Å; E242-M504 HydrophobicContact CG-CE 3.9Å; E242-M504 HydrophobicContact CG-CG 3.92Å; E242-M504 HydrophobicContact CG-SD 3.64Å; V278-M504 HydrophobicContact CG1-CE 4.04Å; V278-M504 HydrophobicContact CG1-SD 3.72Å; V278-M504 HydrophobicContact CG2-CE 4.28Å; V278-M504 HydrophobicContact CG2-SD 4.39Å; L280-M504 HydrophobicContact CB-CE 4.07Å; L280-M504 HydrophobicContact CD2-CB 4.26Å; I500-M504 HydrophobicContact CG2-CG 4.42Å; I500-M504 HydrophobicContact CG2-SD 4.42Å; I500-M504 WeakPolarHBondContact O-CG 3.27Å; I500-M504 PolarHBondContact O-N 3.34Å; Y501-M504 PolarHBondContact O-N 2.78Å; M504-A506 VanDerWaalsContact C-N 3.35Å; M504-A506 PolarHBondContact O-N 2.62Å; M504-N507 PolarHBondContact O-N 3.03Å; M504-N508 PolarHBondContact O-N 3.24Å
505W94Very high90.4Very high4 Ų433 Ų332%0.01516%0.159CC..Hα-helixtrans-67.9-32.6178.5-8596.1000113.2L280 T310 N466 Q469 A470 A473 Y501 I503 G509 T527L280-W505 HydrophobicContact CD1-CD2 4.4Å; L280-W505 HydrophobicContact CD1-CH2 4.05Å; L280-W505 HydrophobicContact CD1-CZ2 3.6Å; L280-W505 HydrophobicContact CD2-CD2 3.73Å; L280-W505 HydrophobicContact CD2-CE3 4.27Å; L280-W505 HydrophobicContact CD2-CG 3.85Å; L280-W505 HydrophobicContact CD2-CZ2 4.43Å; T310-W505 HydrophobicContact CG2-CH2 3.49Å; T310-W505 VanDerWaalsContact CG2-CH2 3.49Å; T310-W505 HydrophobicContact CG2-CZ2 4.3Å; T310-W505 HydrophobicContact CG2-CZ3 3.89Å; N466-W505 PolarHBondContact ND2-O 3.27Å; Q469-W505 HydrophobicContact CB-CH2 3.84Å; Q469-W505 HydrophobicContact CB-CZ3 3.64Å; A470-W505 HydrophobicContact CB-CB 3.91Å; A470-W505 HydrophobicContact CB-CD2 3.52Å; A470-W505 HydrophobicContact CB-CE3 3.74Å; A470-W505 HydrophobicContact CB-CG 3.59Å; A470-W505 HydrophobicContact CB-CZ3 4.44Å; A473-W505 HydrophobicContact CB-CH2 4.22Å; A473-W505 HydrophobicContact CB-CZ2 3.45Å; A473-W505 VanDerWaalsContact CB-CZ2 3.45Å; Y501-W505 AromaticContact CD2-CD1 3.97Å; Y501-W505 AromaticContact CE1-CD1 3.69Å; Y501-W505 AromaticContact CE1-NE1 3.98Å; Y501-W505 AromaticContact CE2-CD1 3.52Å; Y501-W505 AromaticContact CE2-NE1 3.23Å; Y501-W505 AromaticContact CZ-CD1 3.35Å; Y501-W505 AromaticContact CZ-NE1 3.16Å; Y501-W505 PolarHBondContact O-N 3.34Å; Y501-W505 PolarHBondContact OH-NE1 2.81Å; I503-W505 PolarHBondContact O-N 3.15Å; W505-G509 PolarHBondContact O-N 3.14Å; W505-T527 HydrophobicContact CB-CG2 4.2Å
506A90.5Very high90.2Very high2 Ų229.3 Ų29.32%0.01713%0.133CC..Hα-helixtrans-69.2-35.6172.300000112.6Q502 I503 M504 G509 D510 T527 R528Q502-A506 WeakPolarHBondContact O-CB 3.43Å; Q502-A506 PolarHBondContact O-N 3.17Å; I503-A506 PolarHBondContact O-N 2.95Å; M504-A506 VanDerWaalsContact C-N 3.35Å; M504-A506 PolarHBondContact O-N 2.62Å; A506-G509 PolarHBondContact O-N 3.01Å; A506-D510 WeakPolarHBondContact O-CB 3.47Å; A506-D510 PolarHBondContact O-N 3.44Å; A506-T527 HydrophobicContact CB-CG2 3.85Å; A506-R528 HydrophobicContact CB-CB 4.49Å; A506-R528 HydrophobicContact CB-CG 3.24Å
507N93.1Very high89.8Confident43 Ų4325.8 Ų25.823%0.2312%0.118CC..Hα-helixtrans-69.5-38.7175.1-71.1-14.3000112F238 Q240 I503 M504 S511 R528F238-N507 HydrophobicContact CE2-CB 3.8Å; F238-N507 HydrophobicContact CZ-CB 3.59Å; Q240-N507 PolarHBondContact OE1-ND2 2.9Å; I503-N507 WeakPolarHBondContact O-CB 3.44Å; I503-N507 PolarHBondContact O-N 3.29Å; I503-N507 PolarHBondContact O-ND2 3Å; M504-N507 PolarHBondContact O-N 3.03Å; N507-S511 WeakPolarHBondContact O-CB 3.21Å; N507-S511 PolarHBondContact O-N 2.71Å; N507-S511 PolarHBondContact O-OG 3.47Å; N507-R528 PolarHBondContact OD1-NH1 3.12Å
508N93.9Very high89.3Confident0 Ų027 Ų270%013%0.13CC..Hα-helixtrans-57.5-54.1169.3-178.53.2000110.4F238 L280 S282 R327 M504 D510 S511 I512F238-N508 HydrophobicContact CD1-CB 3.59Å; F238-N508 HydrophobicContact CE1-CB 3.68Å; F238-N508 HydrophobicContact CG-CB 4.21Å; F238-N508 HydrophobicContact CZ-CB 4.35Å; L280-N508 HydrophobicContact CD2-CB 3.78Å; L280-N508 HydrophobicContact CG-CB 4.48Å; S282-N508 PolarHBondContact OG-ND2 3.12Å; S282-N508 PolarHBondContact OG-OD1 2.87Å; S282-N508 VanDerWaalsContact OG-OD1 3.05Å; R327-N508 PolarHBondContact NH2-ND2 3.04Å; R327-N508 PolarHBondContact NH2-OD1 3.15Å; R327-N508 VanDerWaalsContact NH2-OD1 3.12Å; M504-N508 PolarHBondContact O-N 3.24Å; N508-D510 PolarHBondContact O-N 2.89Å; N508-S511 PolarHBondContact O-N 2.79Å; N508-S511 VanDerWaalsContact O-N 3.12Å; N508-I512 PolarHBondContact O-N 2.89Å; N508-I512 WeakPolarHBondContact OD1-CG1 3.46Å
509G91.1Very high88.7Confident3 Ų326.1 Ų26.13%0.03113%0.126CC..Hα-helixtrans-52.7-52.1176.600000112.3L462 N466 W505 A506 S511 S513L462-G509 WeakPolarHBondContact CD2-O 3.49Å; N466-G509 WeakPolarHBondContact OD1-CA 3.32Å; N466-G509 PolarHBondContact OD1-N 3.27Å; W505-G509 PolarHBondContact O-N 3.14Å; A506-G509 PolarHBondContact O-N 3.01Å; G509-S511 VanDerWaalsContact C-N 3.32Å; G509-S511 PolarHBondContact O-N 3.23Å; G509-S513 WeakPolarHBondContact O-CB 3.27Å; G509-S513 PolarHBondContact O-N 3.49Å
510D89.1Confident88.1Confident15 Ų1519.2 Ų19.28%0.0810%0.104CC..Hα-helixtrans-57.2-41.5177.1-94.7-2.5000113.6A506 N508 S513 R514 A520 A521 R528A506-D510 WeakPolarHBondContact O-CB 3.47Å; A506-D510 PolarHBondContact O-N 3.44Å; N508-D510 PolarHBondContact O-N 2.89Å; D510-S513 PolarHBondContact O-N 2.93Å; D510-R514 WeakPolarHBondContact O-CG 3.3Å; D510-R514 PolarHBondContact O-N 3.28Å; D510-A520 WeakPolarHBondContact OD1-CB 3.45Å; D510-A521 WeakPolarHBondContact OD1-CB 3.3Å; D510-A521 PolarHBondContact OD1-N 2.99Å; D510-R528 IonicContact OD1-NH2 3.89Å; D510-R528 IonicContact OD2-CZ 2.76Å; D510-R528 IonicContact OD2-NH2 3.94Å; D510-R528 PolarHBondContact OD2-NH2 2.84Å
511S91.3Very high87.1Confident8 Ų817 Ų176%0.0569%0.093CC..Hα-helixtrans-73.2-48.6-173.8-570000112.2F238 N507 N508 G509 S513 R514 Q515F238-S511 VanDerWaalsContact CD2-OG 3.31Å; F238-S511 WeakPolarHBondContact CD2-OG 3.15Å; N507-S511 WeakPolarHBondContact O-CB 3.21Å; N507-S511 PolarHBondContact O-N 2.71Å; N507-S511 PolarHBondContact O-OG 3.47Å; N508-S511 PolarHBondContact O-N 2.79Å; N508-S511 VanDerWaalsContact O-N 3.12Å; G509-S511 VanDerWaalsContact C-N 3.32Å; G509-S511 PolarHBondContact O-N 3.23Å; S511-S513 PolarHBondContact O-N 2.89Å; S511-R514 PolarHBondContact O-N 3.46Å; S511-R514 PolarHBondContact OG-NH2 3.08Å; S511-Q515 WeakPolarHBondContact O-CG 3.43Å; S511-Q515 PolarHBondContact O-N 3.38Å; S511-Q515 PolarHBondContact O-NE2 3.27Å
512I91.3Very high86Confident5 Ų518.2 Ų18.23%0.02610%0.1CC..Hα-helixtrans-66.1-29.9174.8-54.4-56.7000110.5F238 V308 L462 N508 Q515 Y516F238-I512 HydrophobicContact CB-CD1 4.34Å; V308-I512 HydrophobicContact CG2-CG2 4.16Å; L462-I512 HydrophobicContact CD1-CB 4.35Å; L462-I512 HydrophobicContact CD1-CG2 3.73Å; L462-I512 HydrophobicContact CD2-CB 3.7Å; L462-I512 HydrophobicContact CD2-CG2 3.87Å; L462-I512 HydrophobicContact CG-CG2 4.47Å; N508-I512 PolarHBondContact O-N 2.89Å; N508-I512 WeakPolarHBondContact OD1-CG1 3.46Å; I512-Q515 WeakPolarHBondContact O-CB 3.38Å; I512-Q515 PolarHBondContact O-N 3.29Å; I512-Y516 WeakPolarHBondContact O-CB 3.41Å; I512-Y516 PolarHBondContact O-N 3.23Å; I512-Y516 VanDerWaalsContact O-N 3.15Å
513S88.4Confident84.9Confident2 Ų218.7 Ų18.71%0.01410%0.102CC..Hα-helixtrans-67.3-40174.2-144.20000112.2G509 D510 S511 Q515 Y516 A517 G518 T519 R547G509-S513 WeakPolarHBondContact O-CB 3.27Å; G509-S513 PolarHBondContact O-N 3.49Å; D510-S513 PolarHBondContact O-N 2.93Å; S511-S513 PolarHBondContact O-N 2.89Å; S513-Q515 VanDerWaalsContact C-N 3.25Å; S513-Q515 PolarHBondContact O-N 3.1Å; S513-Y516 PolarHBondContact O-N 3.34Å; S513-A517 PolarHBondContact O-N 2.82Å; S513-G518 PolarHBondContact O-N 3.41Å; S513-T519 CarbonylContact C-O 3.51Å; S513-T519 WeakPolarHBondContact CB-O 3.44Å; S513-R547 PolarHBondContact OG-NH2 3.34Å
514R87.3Confident83.2Confident61 Ų6116.1 Ų16.123%0.239%0.091CC..Hα-helixtrans-60.3-36.4173-76.9-174.9-70-90.62.9111.9D510 S511 G518 T519 R558D510-R514 WeakPolarHBondContact O-CG 3.3Å; D510-R514 PolarHBondContact O-N 3.28Å; S511-R514 PolarHBondContact O-N 3.46Å; S511-R514 PolarHBondContact OG-NH2 3.08Å; R514-G518 VanDerWaalsContact O-CA 3.31Å; R514-G518 WeakPolarHBondContact O-CA 3.41Å; R514-G518 PolarHBondContact O-N 2.93Å; R514-T519 VanDerWaalsContact CA-O 3.29Å; R514-T519 WeakPolarHBondContact CA-O 3.46Å; R514-T519 PolarHBondContact N-O 3.05Å; R514-R558 PolarHBondContact O-NH2 2.87Å
515Q87.1Confident81.5Confident1 Ų117.3 Ų17.31%0.00510%0.097CC..Hα-helixtrans-72.4-28.8-179.9-70.4161.527.500114.2S175 Q236 G237 R284 S511 I512 S513S175-Q515 WeakPolarHBondContact OG-CG 3.29Å; S175-Q515 PolarHBondContact OG-NE2 3.43Å; Q236-Q515 HydrophobicContact CG-CG 4.44Å; G237-Q515 PolarHBondContact O-NE2 3.12Å; R284-Q515 PolarHBondContact NH1-O 3.08Å; R284-Q515 PolarHBondContact NH2-O 3.33Å; R284-Q515 VanDerWaalsContact NH2-O 3.11Å; S511-Q515 WeakPolarHBondContact O-CG 3.43Å; S511-Q515 PolarHBondContact O-N 3.38Å; S511-Q515 PolarHBondContact O-NE2 3.27Å; I512-Q515 WeakPolarHBondContact O-CB 3.38Å; I512-Q515 PolarHBondContact O-N 3.29Å; S513-Q515 VanDerWaalsContact C-N 3.25Å; S513-Q515 PolarHBondContact O-N 3.1Å
516Y81.2Confident79.9Confident34 Ų3418.5 Ų18.513%0.13310%0.102CC..Hα-helixtrans-103.3-36.8-174176.1-117.1000114M291 R292 R296 N306 I512 S513M291-Y516 WeakPolarHBondContact CE-O 3.36Å; R292-Y516 HydrophobicContact CB-CD1 4.31Å; R292-Y516 HydrophobicContact CB-CE1 3.9Å; R292-Y516 HydrophobicContact CB-CE2 4.13Å; R292-Y516 HydrophobicContact CG-CE1 3.77Å; R292-Y516 PolarHBondContact N-O 3.5Å; R296-Y516 PolarHBondContact NH1-OH 2.7Å; N306-Y516 HydrophobicContact CB-CD2 4.12Å; N306-Y516 HydrophobicContact CB-CE2 4.21Å; N306-Y516 WeakPolarHBondContact ND2-CE2 3.46Å; I512-Y516 WeakPolarHBondContact O-CB 3.41Å; I512-Y516 PolarHBondContact O-N 3.23Å; I512-Y516 VanDerWaalsContact O-N 3.15Å; S513-Y516 PolarHBondContact O-N 3.34Å
517A80.4Confident78.7Confident4 Ų419.4 Ų19.43%0.03311%0.107CC..Hα-helixtrans-129.16.4-172.900000113.8S513 T519 R547S513-A517 PolarHBondContact O-N 2.82Å; A517-T519 PolarHBondContact O-N 3.32Å; A517-T519 VanDerWaalsContact O-N 3.14Å; A517-R547 HydrophobicContact CB-CG 4.43Å
518G79.3Confident77.8Confident26 Ų2620 Ų2027%0.26811%0.107SC..SBendtrans72.70.4173.300000116.1S513 R514 L550S513-G518 PolarHBondContact O-N 3.41Å; R514-G518 VanDerWaalsContact O-CA 3.31Å; R514-G518 WeakPolarHBondContact O-CA 3.41Å; R514-G518 PolarHBondContact O-N 2.93Å; G518-L550 VanDerWaalsContact O-CD1 3.3Å; G518-L550 WeakPolarHBondContact O-CD1 3.3Å
519T75.2Confident76Confident10 Ų1023 Ų236%0.06113%0.125CC..SBendtrans-130.6169.6177.674.30000111.3S513 R514 A517 N546 R547 L550S513-T519 CarbonylContact C-O 3.51Å; S513-T519 WeakPolarHBondContact CB-O 3.44Å; R514-T519 VanDerWaalsContact CA-O 3.29Å; R514-T519 WeakPolarHBondContact CA-O 3.46Å; R514-T519 PolarHBondContact N-O 3.05Å; A517-T519 PolarHBondContact O-N 3.32Å; A517-T519 VanDerWaalsContact O-N 3.14Å; T519-N546 HydrophobicContact CG2-CB 3.82Å; T519-R547 HydrophobicContact CG2-CB 4.46Å; T519-R547 HydrophobicContact CG2-CG 3.62Å; T519-R547 VanDerWaalsContact OG1-CG 3.29Å; T519-R547 WeakPolarHBondContact OG1-CG 3.29Å; T519-R547 PolarHBondContact OG1-NE 3.01Å; T519-L550 HydrophobicContact CG2-CD1 3.86Å
520A75.6Confident74.4Confident16 Ų1624.5 Ų24.513%0.13214%0.14CC..PPolyproline II helixtrans-52.3167.3160.900000112.8D510 R547D510-A520 WeakPolarHBondContact OD1-CB 3.45Å; A520-R547 PolarHBondContact O-NH2 2.99Å
521A71.6Confident72.9Confident9 Ų929.6 Ų29.67%0.07416%0.164CC..PPolyproline II helixtrans-62.4154.8173.500000111.1D463 D510 N543D463-A521 VanDerWaalsContact OD1-CA 3.31Å; D463-A521 WeakPolarHBondContact OD1-CA 3.31Å; D463-A521 WeakPolarHBondContact OD1-CB 3.49Å; D510-A521 WeakPolarHBondContact OD1-CB 3.3Å; D510-A521 PolarHBondContact OD1-N 2.99Å; A521-N543 PolarHBondContact O-ND2 3.32Å
522L69.4Low71.5Confident34 Ų3432.7 Ų32.718%0.17817%0.174CC..SBendtrans-87.7153.9159.5-60.2172000108.1D463 G524 D540 N543D463-L522 WeakPolarHBondContact CB-O 3.47Å; D463-L522 VanDerWaalsContact CG-N 3.32Å; D463-L522 PolarHBondContact OD1-N 2.93Å; D463-L522 WeakPolarHBondContact OD2-CB 3.48Å; L522-G524 PolarHBondContact O-N 3.45Å; L522-G524 VanDerWaalsContact O-N 3.1Å; L522-D540 VanDerWaalsContact CA-OD1 3.25Å; L522-D540 WeakPolarHBondContact CA-OD1 3.22Å; L522-D540 HydrophobicContact CD2-CB 3.79Å; L522-D540 VanDerWaalsContact CD2-O 3.28Å; L522-D540 WeakPolarHBondContact CD2-O 3.49Å; L522-N543 HydrophobicContact CD2-CB 3.61Å
523K65.9Low70.3Confident53 Ų5337.5 Ų37.523%0.2320%0.195CC..SBendtrans57.721.3-175.6-50.8168.8166.5-169.10113.1F419 D525 F526 T527 D540F419-K523 HydrophobicContact CE1-CD 4.08Å; F419-K523 HydrophobicContact CZ-CD 3.71Å; F419-K523 HydrophobicContact CZ-CG 4.47Å; K523-D525 WeakPolarHBondContact CA-OD1 3.23Å; K523-D525 PolarHBondContact O-N 2.93Å; K523-F526 PolarHBondContact O-N 3.4Å; K523-T527 PolarHBondContact O-N 2.84Å; K523-D540 VanDerWaalsContact N-CG 3.35Å; K523-D540 PolarHBondContact N-OD1 3.49Å; K523-D540 VanDerWaalsContact N-OD1 3.09Å; K523-D540 PolarHBondContact N-OD2 2.89Å
524G57.8Low68.7Low8 Ų845 Ų458%0.08223%0.234CC..THydrogen-bonded Turntrans-71.9-1.3175.900000113.5L522 R528L522-G524 PolarHBondContact O-N 3.45Å; L522-G524 VanDerWaalsContact O-N 3.1Å; G524-R528 PolarHBondContact O-NE 3.36Å
525D58.9Low67.1Low26 Ų2645.8 Ų45.814%0.13925%0.253CS..THydrogen-bonded Turntrans-80.1-52.6163.461.9-29.8000110.7K523 T527 R528 T529 R532 K533K523-D525 WeakPolarHBondContact CA-OD1 3.23Å; K523-D525 PolarHBondContact O-N 2.93Å; D525-T527 VanDerWaalsContact C-N 3.26Å; D525-T527 PolarHBondContact O-N 2.79Å; D525-T527 VanDerWaalsContact O-N 3.17Å; D525-R528 WeakPolarHBondContact O-CA 3.2Å; D525-R528 PolarHBondContact O-N 2.97Å; D525-T529 PolarHBondContact O-N 3.4Å; D525-T529 VanDerWaalsContact O-N 3.16Å; D525-T529 PolarHBondContact O-OG1 2.85Å; D525-T529 VanDerWaalsContact O-OG1 3.09Å; D525-R532 WeakPolarHBondContact OD2-CA 3.32Å; D525-R532 WeakPolarHBondContact OD2-CG 3.47Å; D525-K533 PolarHBondContact OD2-N 3.48Å
526F59.9Low65.8Low29 Ų2946.2 Ų46.213%0.12726%0.258CS..Hα-helixtrans-51.1-43.9178.4168.4-96.6000112.6F419 V467 K523 R528 T529 G530 E531F419-F526 HydrophobicContact CB-CD1 4.37Å; F419-F526 HydrophobicContact CB-CD2 4.08Å; F419-F526 HydrophobicContact CB-CE1 3.71Å; F419-F526 HydrophobicContact CB-CE2 3.34Å; F419-F526 HydrophobicContact CB-CZ 3.15Å; F419-F526 HydrophobicContact CD1-CD1 4.31Å; F419-F526 HydrophobicContact CD1-CE1 4.21Å; F419-F526 HydrophobicContact CD1-CZ 4.48Å; F419-F526 HydrophobicContact CD2-CD1 4.07Å; F419-F526 AromaticContact CD2-CD2 3.39Å; F419-F526 HydrophobicContact CD2-CD2 3.39Å; F419-F526 HydrophobicContact CD2-CE1 4.25Å; F419-F526 AromaticContact CD2-CE2 3.59Å; F419-F526 HydrophobicContact CD2-CE2 3.59Å; F419-F526 AromaticContact CD2-CG 3.67Å; F419-F526 HydrophobicContact CD2-CG 3.67Å; F419-F526 HydrophobicContact CD2-CZ 4.05Å; F419-F526 HydrophobicContact CE2-CB 4.33Å; F419-F526 HydrophobicContact CE2-CD1 4.42Å; F419-F526 HydrophobicContact CE2-CD2 4.02Å; F419-F526 AromaticContact CE2-CG 3.94Å; F419-F526 HydrophobicContact CE2-CG 3.94Å; F419-F526 HydrophobicContact CG-CD1 4.02Å; F419-F526 AromaticContact CG-CD2 3.93Å; F419-F526 HydrophobicContact CG-CD2 3.93Å; F419-F526 AromaticContact CG-CE1 3.83Å; F419-F526 HydrophobicContact CG-CE1 3.83Å; F419-F526 AromaticContact CG-CE2 3.72Å; F419-F526 HydrophobicContact CG-CE2 3.72Å; F419-F526 HydrophobicContact CG-CG 4.1Å; F419-F526 AromaticContact CG-CZ 3.7Å; F419-F526 HydrophobicContact CG-CZ 3.7Å; V467-F526 HydrophobicContact CG1-CE1 3.86Å; V467-F526 HydrophobicContact CG2-CD1 4.01Å; V467-F526 HydrophobicContact CG2-CE1 3.95Å; K523-F526 PolarHBondContact O-N 3.4Å; F526-R528 PolarHBondContact O-N 3.29Å; F526-R528 VanDerWaalsContact O-N 3.16Å; F526-T529 PolarHBondContact O-N 2.94Å; F526-G530 VanDerWaalsContact CD2-O 3.26Å; F526-G530 WeakPolarHBondContact CD2-O 3.33Å; F526-G530 WeakPolarHBondContact CE2-O 3.24Å; F526-G530 WeakPolarHBondContact O-CA 3.31Å; F526-G530 PolarHBondContact O-N 2.71Å; F526-E531 WeakPolarHBondContact CA-O 3.4Å
527T64.6Low65Low20 Ų2047.6 Ų47.612%0.12327%0.27CS..Hα-helixtrans-63.9-22.3-179.9-48.50000112.9Q502 W505 A506 K523 D525Q502-T527 CarbonylContact C-O 3.58Å; Q502-T527 WeakPolarHBondContact CA-O 3.31Å; Q502-T527 VanDerWaalsContact CB-O 3.24Å; Q502-T527 WeakPolarHBondContact CB-O 3.31Å; Q502-T527 VanDerWaalsContact O-O 3.1Å; W505-T527 HydrophobicContact CB-CG2 4.2Å; A506-T527 HydrophobicContact CB-CG2 3.85Å; K523-T527 PolarHBondContact O-N 2.84Å; D525-T527 VanDerWaalsContact C-N 3.26Å; D525-T527 PolarHBondContact O-N 2.79Å; D525-T527 VanDerWaalsContact O-N 3.17Å
528R75.3Confident64Low57 Ų5754.4 Ų54.422%0.21530%0.303CS..Hα-helixtrans-94.9-23.5-179.9-63.6179.2-141.9-100.4-8.5114.7Q502 A506 N507 D510 G524 D525 F526Q502-R528 PolarHBondContact OE1-O 3.4Å; A506-R528 HydrophobicContact CB-CB 4.49Å; A506-R528 HydrophobicContact CB-CG 3.24Å; N507-R528 PolarHBondContact OD1-NH1 3.12Å; D510-R528 IonicContact OD1-NH2 3.89Å; D510-R528 IonicContact OD2-CZ 2.76Å; D510-R528 IonicContact OD2-NH2 3.94Å; D510-R528 PolarHBondContact OD2-NH2 2.84Å; G524-R528 PolarHBondContact O-NE 3.36Å; D525-R528 WeakPolarHBondContact O-CA 3.2Å; D525-R528 PolarHBondContact O-N 2.97Å; F526-R528 PolarHBondContact O-N 3.29Å; F526-R528 VanDerWaalsContact O-N 3.16Å
529T55.3Low63.4Low62 Ų6258.7 Ų58.738%0.3831%0.314SS..Hα-helixtrans-130.2-4.6-17045.60000114.9D525 F526 E531D525-T529 PolarHBondContact O-N 3.4Å; D525-T529 VanDerWaalsContact O-N 3.16Å; D525-T529 PolarHBondContact O-OG1 2.85Å; D525-T529 VanDerWaalsContact O-OG1 3.09Å; F526-T529 PolarHBondContact O-N 2.94Å; T529-E531 PolarHBondContact O-N 3.41Å; T529-E531 PolarHBondContact OG1-O 3.37Å
530G57.4Low63.2Low35 Ų3558.8 Ų58.836%0.36132%0.315SS..SBendtrans68.4-14.1-171.800000114.4F526F526-G530 VanDerWaalsContact CD2-O 3.26Å; F526-G530 WeakPolarHBondContact CD2-O 3.33Å; F526-G530 WeakPolarHBondContact CE2-O 3.24Å; F526-G530 WeakPolarHBondContact O-CA 3.31Å; F526-G530 PolarHBondContact O-N 2.71Å
531E58.7Low62.7Low122 Ų12260 Ų6057%0.5733%0.328SS*.SBendtrans-118.9156.9178.4-58.7179.3146.600111.3F526 T529 K533F526-E531 WeakPolarHBondContact CA-O 3.4Å; T529-E531 PolarHBondContact O-N 3.41Å; T529-E531 PolarHBondContact OG1-O 3.37Å; E531-K533 WeakPolarHBondContact OE2-CE 3.35Å; E531-K533 IonicContact OE2-NZ 3.38Å
532R60.3Low62.6Low72 Ų7263.4 Ų63.427%0.27235%0.348SS..  trans-104.7127.6173.5-154.8-177-174.1-140.92.9111D525 D540D525-R532 WeakPolarHBondContact OD2-CA 3.32Å; D525-R532 WeakPolarHBondContact OD2-CG 3.47Å; R532-D540 IonicContact CZ-OD2 3.56Å; R532-D540 IonicContact NE-OD2 2.72Å; R532-D540 IonicContact NH2-OD2 2.71Å; R532-D540 PolarHBondContact NH2-OD2 3.44Å
533K65.8Low62.7Low107 Ų10762.6 Ų62.647%0.46534%0.344SS..  trans-109.2148.9-173.2-57-166179.4-1620111.1D525 E531 A535 G536 V537D525-K533 PolarHBondContact OD2-N 3.48Å; E531-K533 WeakPolarHBondContact OE2-CE 3.35Å; E531-K533 IonicContact OE2-NZ 3.38Å; K533-A535 VanDerWaalsContact C-N 3.26Å; K533-A535 PolarHBondContact O-N 2.74Å; K533-G536 VanDerWaalsContact O-CA 3.29Å; K533-G536 WeakPolarHBondContact O-CA 3.47Å; K533-G536 PolarHBondContact O-N 2.67Å; K533-V537 PolarHBondContact O-N 2.91Å; K533-V537 VanDerWaalsContact O-N 3.11Å
534L56.7Low62.8Low158 Ų15861.1 Ų61.183%0.82734%0.34SS*.Hα-helixtrans-54-41.6-175.4-170.875.8000112.7G536 V537 M538L534-G536 VanDerWaalsContact C-N 3.29Å; L534-G536 PolarHBondContact O-N 2.93Å; L534-V537 WeakPolarHBondContact O-CB 3.25Å; L534-V537 PolarHBondContact O-N 2.73Å; L534-V537 VanDerWaalsContact O-N 3.14Å; L534-M538 PolarHBondContact O-N 3.47Å; L534-M538 VanDerWaalsContact O-N 3.1Å
535A52.6Low63.2Low78 Ų7863.5 Ų63.565%0.64536%0.359SS*.Hα-helixtrans-63.2-32174.400000113.2K533 M538 K539K533-A535 VanDerWaalsContact C-N 3.26Å; K533-A535 PolarHBondContact O-N 2.74Å; A535-M538 PolarHBondContact O-N 2.76Å; A535-K539 WeakPolarHBondContact O-CB 3.25Å; A535-K539 PolarHBondContact O-N 3.35Å
536G59.5Low63.8Low10 Ų1065.9 Ų65.910%0.10337%0.372CS..Hα-helixtrans-65.5-40.9171.300000112.2K533 L534 M538 K539 D540K533-G536 VanDerWaalsContact O-CA 3.29Å; K533-G536 WeakPolarHBondContact O-CA 3.47Å; K533-G536 PolarHBondContact O-N 2.67Å; L534-G536 VanDerWaalsContact C-N 3.29Å; L534-G536 PolarHBondContact O-N 2.93Å; G536-M538 VanDerWaalsContact C-N 3.34Å; G536-M538 PolarHBondContact O-N 3.4Å; G536-K539 PolarHBondContact O-N 3.26Å; G536-D540 WeakPolarHBondContact O-CB 3.42Å; G536-D540 PolarHBondContact O-N 2.75Å
537V64.4Low64.6Low64 Ų6465.4 Ų65.439%0.38837%0.369SS..Hα-helixtrans-61.4-41.6173.6-167.80000111.5K533 L534 D540 G541K533-V537 PolarHBondContact O-N 2.91Å; K533-V537 VanDerWaalsContact O-N 3.11Å; L534-V537 WeakPolarHBondContact O-CB 3.25Å; L534-V537 PolarHBondContact O-N 2.73Å; L534-V537 VanDerWaalsContact O-N 3.14Å; V537-D540 PolarHBondContact O-N 2.72Å; V537-G541 PolarHBondContact O-N 3Å
538M60.9Low64.8Low147 Ų14768.6 Ų68.672%0.72438%0.38SS*.Hα-helixtrans-66.1-43.3175.8-171179.1-178.300112.1L534 A535 G536 D540 G541 V542L534-M538 PolarHBondContact O-N 3.47Å; L534-M538 VanDerWaalsContact O-N 3.1Å; A535-M538 PolarHBondContact O-N 2.76Å; G536-M538 VanDerWaalsContact C-N 3.34Å; G536-M538 PolarHBondContact O-N 3.4Å; M538-D540 VanDerWaalsContact C-N 3.33Å; M538-D540 PolarHBondContact O-N 3.21Å; M538-G541 PolarHBondContact O-N 3.39Å; M538-G541 VanDerWaalsContact O-N 3.14Å; M538-V542 PolarHBondContact O-N 3.36Å; M538-V542 VanDerWaalsContact O-N 3.1Å
539K66.1Low64.6Low116 Ų11671.7 Ų71.750%0.50439%0.392SS..Hα-helixtrans-60.8-40.7174.5-174.4-179.7178.2-175.50111.8A535 G536 G541 V542 N543A535-K539 WeakPolarHBondContact O-CB 3.25Å; A535-K539 PolarHBondContact O-N 3.35Å; G536-K539 PolarHBondContact O-N 3.26Å; K539-G541 VanDerWaalsContact C-N 3.31Å; K539-G541 PolarHBondContact O-N 2.73Å; K539-V542 PolarHBondContact O-N 3.23Å; K539-N543 WeakPolarHBondContact O-CB 3.34Å; K539-N543 PolarHBondContact O-N 2.99Å
540D69.6Low65.5Low12 Ų1270.2 Ų70.26%0.06438%0.382CS..Hα-helixtrans-63.2-35.7174.2-83.8-0.9000112.2L522 K523 R532 G536 V537 M538 S544L522-D540 VanDerWaalsContact CA-OD1 3.25Å; L522-D540 WeakPolarHBondContact CA-OD1 3.22Å; L522-D540 HydrophobicContact CD2-CB 3.79Å; L522-D540 VanDerWaalsContact CD2-O 3.28Å; L522-D540 WeakPolarHBondContact CD2-O 3.49Å; K523-D540 VanDerWaalsContact N-CG 3.35Å; K523-D540 PolarHBondContact N-OD1 3.49Å; K523-D540 VanDerWaalsContact N-OD1 3.09Å; K523-D540 PolarHBondContact N-OD2 2.89Å; R532-D540 IonicContact CZ-OD2 3.56Å; R532-D540 IonicContact NE-OD2 2.72Å; R532-D540 IonicContact NH2-OD2 2.71Å; R532-D540 PolarHBondContact NH2-OD2 3.44Å; G536-D540 WeakPolarHBondContact O-CB 3.42Å; G536-D540 PolarHBondContact O-N 2.75Å; V537-D540 PolarHBondContact O-N 2.72Å; M538-D540 VanDerWaalsContact C-N 3.33Å; M538-D540 PolarHBondContact O-N 3.21Å; D540-S544 VanDerWaalsContact O-CB 3.23Å; D540-S544 WeakPolarHBondContact O-CB 3.17Å; D540-S544 PolarHBondContact O-N 2.97Å; D540-S544 PolarHBondContact O-OG 3.27Å
541G66.3Low66.1Low41 Ų4169.7 Ų69.742%0.42337%0.371SS..Hα-helixtrans-62.3-4717200000112.7V537 M538 K539 S544 A545V537-G541 PolarHBondContact O-N 3Å; M538-G541 PolarHBondContact O-N 3.39Å; M538-G541 VanDerWaalsContact O-N 3.14Å; K539-G541 VanDerWaalsContact C-N 3.31Å; K539-G541 PolarHBondContact O-N 2.73Å; G541-S544 WeakPolarHBondContact O-CB 3.45Å; G541-S544 PolarHBondContact O-N 2.91Å; G541-A545 PolarHBondContact O-N 3Å
542V68.4Low66.5Low80 Ų8066.6 Ų66.649%0.48535%0.354SS..Hα-helixtrans-64.8-44.8176.2177.20000111.4M538 K539 S544 A545 N546M538-V542 PolarHBondContact O-N 3.36Å; M538-V542 VanDerWaalsContact O-N 3.1Å; K539-V542 PolarHBondContact O-N 3.23Å; V542-S544 VanDerWaalsContact C-N 3.28Å; V542-S544 PolarHBondContact O-N 3.45Å; V542-A545 PolarHBondContact O-N 3.11Å; V542-N546 WeakPolarHBondContact O-CB 3.4Å; V542-N546 PolarHBondContact O-N 3.18Å; V542-N546 PolarHBondContact O-ND2 3.48Å
543N72.8Confident66.9Low17 Ų1767.9 Ų67.99%0.09136%0.362CS..Hα-helixtrans-58-40.5173.5-80.6-14.8000111.5A521 L522 K539 N546 R547A521-N543 PolarHBondContact O-ND2 3.32Å; L522-N543 HydrophobicContact CD2-CB 3.61Å; K539-N543 WeakPolarHBondContact O-CB 3.34Å; K539-N543 PolarHBondContact O-N 2.99Å; N543-N546 PolarHBondContact O-N 3.24Å; N543-R547 WeakPolarHBondContact O-CB 3.44Å; N543-R547 WeakPolarHBondContact O-CG 3.26Å; N543-R547 PolarHBondContact O-N 3.23Å
544S68.4Low67.3Low23 Ų2365.5 Ų65.516%0.16135%0.351CS..Hα-helixtrans-66-42.9178.8-65.10000112.7Y341 D540 G541 V542 R547 Y548Y341-S544 WeakPolarHBondContact OH-CB 3.32Å; D540-S544 VanDerWaalsContact O-CB 3.23Å; D540-S544 WeakPolarHBondContact O-CB 3.17Å; D540-S544 PolarHBondContact O-N 2.97Å; D540-S544 PolarHBondContact O-OG 3.27Å; G541-S544 WeakPolarHBondContact O-CB 3.45Å; G541-S544 PolarHBondContact O-N 2.91Å; V542-S544 VanDerWaalsContact C-N 3.28Å; V542-S544 PolarHBondContact O-N 3.45Å; S544-R547 PolarHBondContact O-N 3.22Å; S544-Y548 PolarHBondContact O-N 2.97Å; S544-Y548 VanDerWaalsContact O-N 3.15Å
545A65.5Low68.5Low58 Ų5858.2 Ų58.248%0.47931%0.313SS..Hα-helixtrans-63.3-42.6173.200000111.9G541 V542 Y548 Y549G541-A545 PolarHBondContact O-N 3Å; V542-A545 PolarHBondContact O-N 3.11Å; A545-Y548 PolarHBondContact O-N 2.99Å; A545-Y549 PolarHBondContact O-N 3.15Å
546N72.2Confident69.8Low75 Ų7555 Ų5540%0.40129%0.287SS..Hα-helixtrans-63.2-45.9175.4-74.8-21000112T519 V542 N543 Y548 Y549 L550T519-N546 HydrophobicContact CG2-CB 3.82Å; V542-N546 WeakPolarHBondContact O-CB 3.4Å; V542-N546 PolarHBondContact O-N 3.18Å; V542-N546 PolarHBondContact O-ND2 3.48Å; N543-N546 PolarHBondContact O-N 3.24Å; N546-Y548 PolarHBondContact O-N 3.32Å; N546-Y549 PolarHBondContact O-N 2.82Å; N546-Y549 VanDerWaalsContact O-N 3.15Å; N546-L550 WeakPolarHBondContact O-CB 3.36Å; N546-L550 VanDerWaalsContact O-CG 3.27Å; N546-L550 WeakPolarHBondContact O-CG 3.46Å; N546-L550 PolarHBondContact O-N 3.23Å
547R75.8Confident71Confident20 Ų2055.1 Ų55.18%0.07528%0.284CS..Hα-helixtrans-54.9-40174.7-76.5179.8-179.2-173.82.3111.6D463 S513 A517 T519 A520 N543 S544 N551D463-R547 IonicContact OD1-NH2 2.85Å; D463-R547 PolarHBondContact OD1-NH2 3.2Å; D463-R547 IonicContact OD2-CZ 2.66Å; D463-R547 IonicContact OD2-NH1 2.71Å; D463-R547 PolarHBondContact OD2-NH1 3.3Å; D463-R547 IonicContact OD2-NH2 3.23Å; S513-R547 PolarHBondContact OG-NH2 3.34Å; A517-R547 HydrophobicContact CB-CG 4.43Å; T519-R547 HydrophobicContact CG2-CB 4.46Å; T519-R547 HydrophobicContact CG2-CG 3.62Å; T519-R547 VanDerWaalsContact OG1-CG 3.29Å; T519-R547 WeakPolarHBondContact OG1-CG 3.29Å; T519-R547 PolarHBondContact OG1-NE 3.01Å; A520-R547 PolarHBondContact O-NH2 2.99Å; N543-R547 WeakPolarHBondContact O-CB 3.44Å; N543-R547 WeakPolarHBondContact O-CG 3.26Å; N543-R547 PolarHBondContact O-N 3.23Å; S544-R547 PolarHBondContact O-N 3.22Å; R547-N551 WeakPolarHBondContact O-CB 3.33Å; R547-N551 PolarHBondContact O-N 3.43Å
548Y68.3Low72.1Confident86 Ų8653.1 Ų53.134%0.33727%0.27SS..Hα-helixtrans-68-43.7176.5176.4-106.1000113Y341 S544 A545 N546 R552Y341-Y548 AromaticContact CD2-CD2 3.62Å; Y341-Y548 HydrophobicContact CD2-CD2 3.62Å; Y341-Y548 HydrophobicContact CD2-CE2 4.35Å; Y341-Y548 AromaticContact CD2-CG 3.82Å; Y341-Y548 HydrophobicContact CD2-CG 3.82Å; Y341-Y548 HydrophobicContact CE2-CD2 4.45Å; Y341-Y548 HydrophobicContact CE2-CG 4.33Å; Y341-Y548 HydrophobicContact CG-CD2 4.36Å; S544-Y548 PolarHBondContact O-N 2.97Å; S544-Y548 VanDerWaalsContact O-N 3.15Å; A545-Y548 PolarHBondContact O-N 2.99Å; N546-Y548 PolarHBondContact O-N 3.32Å; Y548-R552 PolarHBondContact O-N 2.72Å; Y548-R552 VanDerWaalsContact O-N 3.12Å; Y548-R552 PolarHBondContact OH-NH2 2.95Å; Y548-R552 VanDerWaalsContact OH-NH2 3.14Å
549Y72.1Confident73.4Confident123 Ų12346.6 Ų46.648%0.48224%0.238SC..Hα-helixtrans-63.7-45.1176.3176.1-95.3000112.2A545 N546 R552 F553A545-Y549 PolarHBondContact O-N 3.15Å; N546-Y549 PolarHBondContact O-N 2.82Å; N546-Y549 VanDerWaalsContact O-N 3.15Å; Y549-R552 PolarHBondContact O-N 2.67Å; Y549-F553 AromaticContact CD2-CD2 3.51Å; Y549-F553 HydrophobicContact CD2-CD2 3.51Å; Y549-F553 AromaticContact CD2-CE2 3.86Å; Y549-F553 HydrophobicContact CD2-CE2 3.86Å; Y549-F553 AromaticContact CE2-CD2 3.44Å; Y549-F553 HydrophobicContact CE2-CD2 3.44Å; Y549-F553 VanDerWaalsContact CE2-CD2 3.44Å; Y549-F553 AromaticContact CE2-CE2 3.89Å; Y549-F553 HydrophobicContact CE2-CE2 3.89Å; Y549-F553 HydrophobicContact CE2-CG 4.26Å; Y549-F553 HydrophobicContact CG-CD2 4.24Å; Y549-F553 WeakPolarHBondContact O-CD2 3.25Å; Y549-F553 PolarHBondContact O-N 2.66Å
550L73.3Confident74.4Confident31 Ų3141.3 Ų41.316%0.16222%0.215CC..Hα-helixtrans-63.7-48.5179-65.7174.7000111.4G518 T519 N546 R552 F553 K554 D555G518-L550 VanDerWaalsContact O-CD1 3.3Å; G518-L550 WeakPolarHBondContact O-CD1 3.3Å; T519-L550 HydrophobicContact CG2-CD1 3.86Å; N546-L550 WeakPolarHBondContact O-CB 3.36Å; N546-L550 VanDerWaalsContact O-CG 3.27Å; N546-L550 WeakPolarHBondContact O-CG 3.46Å; N546-L550 PolarHBondContact O-N 3.23Å; L550-R552 PolarHBondContact O-N 3.3Å; L550-F553 PolarHBondContact O-N 3.18Å; L550-K554 HydrophobicContact CD2-CB 3.93Å; L550-K554 HydrophobicContact CD2-CD 3.7Å; L550-K554 HydrophobicContact CD2-CG 4.02Å; L550-K554 WeakPolarHBondContact O-CA 3.29Å; L550-K554 PolarHBondContact O-N 3.15Å; L550-D555 VanDerWaalsContact C-OD1 3.23Å; L550-D555 PolarHBondContact O-N 3.46Å
551N69.8Low75.4Confident24 Ų2440.9 Ų40.913%0.12821%0.213CC..Hα-helixtrans-51.8-41.2172.7178.526.7000112.6Y293 R547 D555Y293-N551 HydrophobicContact CD2-CB 4.2Å; Y293-N551 WeakPolarHBondContact CD2-ND2 3.45Å; Y293-N551 WeakPolarHBondContact CD2-OD1 3.27Å; R547-N551 WeakPolarHBondContact O-CB 3.33Å; R547-N551 PolarHBondContact O-N 3.43Å; N551-D555 PolarHBondContact N-OD1 2.63Å
552R68.6Low76.5Confident56 Ų5639 Ų3921%0.21119%0.193CC..Hα-helixtrans-71.6-45.9-179.7-175.156.751.396.615.4113.6Y339 Y548 Y549 L550Y339-R552 PolarHBondContact O-NH2 2.91Å; Y548-R552 PolarHBondContact O-N 2.72Å; Y548-R552 VanDerWaalsContact O-N 3.12Å; Y548-R552 PolarHBondContact OH-NH2 2.95Å; Y548-R552 VanDerWaalsContact OH-NH2 3.14Å; Y549-R552 PolarHBondContact O-N 2.67Å; L550-R552 PolarHBondContact O-N 3.3Å
553F67.8Low77.6Confident99 Ų9935.9 Ų35.943%0.43417%0.174SC..Hα-helixtrans-120.2-17-162.9-61.2-72.3000115.5Y549 L550 Y557Y549-F553 AromaticContact CD2-CD2 3.51Å; Y549-F553 HydrophobicContact CD2-CD2 3.51Å; Y549-F553 AromaticContact CD2-CE2 3.86Å; Y549-F553 HydrophobicContact CD2-CE2 3.86Å; Y549-F553 AromaticContact CE2-CD2 3.44Å; Y549-F553 HydrophobicContact CE2-CD2 3.44Å; Y549-F553 VanDerWaalsContact CE2-CD2 3.44Å; Y549-F553 AromaticContact CE2-CE2 3.89Å; Y549-F553 HydrophobicContact CE2-CE2 3.89Å; Y549-F553 HydrophobicContact CE2-CG 4.26Å; Y549-F553 HydrophobicContact CG-CD2 4.24Å; Y549-F553 WeakPolarHBondContact O-CD2 3.25Å; Y549-F553 PolarHBondContact O-N 2.66Å; L550-F553 PolarHBondContact O-N 3.18Å; F553-Y557 WeakPolarHBondContact O-CD2 3.37Å; F553-Y557 WeakPolarHBondContact O-CE2 3.35Å
554K74.7Confident78.4Confident57 Ų5735.9 Ų35.925%0.24817%0.174CC..THydrogen-bonded Turntrans-123.2-35.4-172.6-70.1-150171-157.60115.4E165 L550 A556 Y557 R558E165-K554 IonicContact OE1-NZ 3.74Å; E165-K554 PolarHBondContact OE1-NZ 3.25Å; L550-K554 HydrophobicContact CD2-CB 3.93Å; L550-K554 HydrophobicContact CD2-CD 3.7Å; L550-K554 HydrophobicContact CD2-CG 4.02Å; L550-K554 WeakPolarHBondContact O-CA 3.29Å; L550-K554 PolarHBondContact O-N 3.15Å; K554-A556 PolarHBondContact O-N 3.44Å; K554-Y557 PolarHBondContact O-N 2.87Å; K554-R558 PolarHBondContact O-N 3.22Å
555D81.2Confident79.4Confident5 Ų534.8 Ų34.83%0.02717%0.166CC..Hα-helixtrans-56.2-25.7-178.9-79.525.1000112.7M291 K294 L550 N551 Q559M291-D555 HydrophobicContact CB-CB 3.89Å; M291-D555 HydrophobicContact CE-CB 4.47Å; M291-D555 WeakPolarHBondContact CE-OD1 3.3Å; M291-D555 HydrophobicContact CG-CB 4.06Å; K294-D555 HydrophobicContact CG-CB 4.41Å; L550-D555 VanDerWaalsContact C-OD1 3.23Å; L550-D555 PolarHBondContact O-N 3.46Å; N551-D555 PolarHBondContact N-OD1 2.63Å; D555-Q559 VanDerWaalsContact O-CB 3.23Å; D555-Q559 WeakPolarHBondContact O-CB 3.49Å; D555-Q559 PolarHBondContact O-N 2.99Å
556A80.8Confident80.6Confident12 Ų1232.8 Ų32.810%0.09915%0.147CC..Hα-helixtrans-66.3-50.4173.100000113K554 Q559 A560 I577K554-A556 PolarHBondContact O-N 3.44Å; A556-Q559 PolarHBondContact O-N 3.48Å; A556-A560 PolarHBondContact O-N 3.05Å; A556-I577 HydrophobicContact CB-CD1 3.78Å; A556-I577 HydrophobicContact CB-CG1 4.23Å; A556-I577 HydrophobicContact CB-CG2 4.32Å
557Y84.4Confident81.3Confident11 Ų1130.5 Ų30.54%0.04314%0.141CC..Hα-helixtrans-67.5-39.2176.3-60.7-78.1000111.4L158 R161 L162 F553 K554 A560 V561 F578L158-Y557 HydrophobicContact CD1-CD1 4.44Å; L158-Y557 HydrophobicContact CD1-CE1 4.22Å; R161-Y557 HydrophobicContact CB-CD1 4.12Å; R161-Y557 HydrophobicContact CB-CE1 4.19Å; R161-Y557 PolarHBondContact NH1-OH 2.74Å; L162-Y557 HydrophobicContact CD2-CD1 4.45Å; F553-Y557 WeakPolarHBondContact O-CD2 3.37Å; F553-Y557 WeakPolarHBondContact O-CE2 3.35Å; K554-Y557 PolarHBondContact O-N 2.87Å; Y557-A560 PolarHBondContact O-N 3.29Å; Y557-V561 WeakPolarHBondContact O-CG2 3.28Å; Y557-V561 PolarHBondContact O-N 2.83Å; Y557-F578 HydrophobicContact CE1-CZ 4.43Å
558R87.9Confident81.8Confident22 Ų2233 Ų338%0.08316%0.155CC..Hα-helixtrans-67.1-35.6176.9-166.1169.5173.5113.1-4112.3M169 S173 M291 R514 K554 I562M169-R558 HydrophobicContact CG-CG 4.13Å; M169-R558 HydrophobicContact SD-CG 3.83Å; S173-R558 PolarHBondContact OG-NH1 3.06Å; S173-R558 PolarHBondContact OG-NH2 3.41Å; M291-R558 HydrophobicContact CG-CB 4.26Å; M291-R558 HydrophobicContact CG-CG 4.41Å; M291-R558 HydrophobicContact SD-CB 4.25Å; M291-R558 HydrophobicContact SD-CG 3.8Å; R514-R558 PolarHBondContact O-NH2 2.87Å; K554-R558 PolarHBondContact O-N 3.22Å; R558-I562 VanDerWaalsContact O-CG1 3.3Å; R558-I562 WeakPolarHBondContact O-CG1 3.27Å; R558-I562 PolarHBondContact O-N 3.37Å; R558-I562 VanDerWaalsContact O-N 3.1Å
559Q88.2Confident81.9Confident11 Ų1133.5 Ų33.55%0.05117%0.169CC..Hα-helixtrans-64.5-45.2169.7-174.467.350.500111.4A289 M291 K294 D555 A556 V561 I562 D563A289-Q559 PolarHBondContact O-NE2 3.28Å; A289-Q559 VanDerWaalsContact O-NE2 3.08Å; M291-Q559 HydrophobicContact CG-CB 4.49Å; K294-Q559 HydrophobicContact CB-CB 4.34Å; K294-Q559 HydrophobicContact CB-CG 4.15Å; K294-Q559 HydrophobicContact CG-CB 4.35Å; D555-Q559 VanDerWaalsContact O-CB 3.23Å; D555-Q559 WeakPolarHBondContact O-CB 3.49Å; D555-Q559 PolarHBondContact O-N 2.99Å; A556-Q559 PolarHBondContact O-N 3.48Å; Q559-V561 VanDerWaalsContact C-N 3.33Å; Q559-V561 PolarHBondContact O-N 3.45Å; Q559-I562 WeakPolarHBondContact O-CB 3.41Å; Q559-I562 PolarHBondContact O-N 2.94Å; Q559-I562 VanDerWaalsContact O-N 3.15Å; Q559-D563 PolarHBondContact NE2-OD1 2.85Å; Q559-D563 WeakPolarHBondContact O-CB 3.48Å; Q559-D563 VanDerWaalsContact O-CG 3.28Å; Q559-D563 PolarHBondContact O-N 3.02Å
560A86.8Confident81.7Confident4 Ų429.6 Ų29.63%0.03316%0.158CC..Hα-helixtrans-59.6-42.4178.200000112.1L162 A556 Y557 D563 L564 V570 L574L162-A560 HydrophobicContact CD2-CB 3.9Å; A556-A560 PolarHBondContact O-N 3.05Å; Y557-A560 PolarHBondContact O-N 3.29Å; A560-D563 PolarHBondContact O-N 3.37Å; A560-L564 WeakPolarHBondContact O-CB 3.46Å; A560-L564 WeakPolarHBondContact O-CG 3.45Å; A560-L564 PolarHBondContact O-N 2.79Å; A560-V570 HydrophobicContact CB-CG1 4.05Å; A560-V570 HydrophobicContact CB-CG2 4.34Å; A560-L574 HydrophobicContact CB-CD1 4Å; A560-L574 HydrophobicContact CB-CD2 4.05Å; A560-L574 HydrophobicContact CB-CG 4.09Å
561V89.6Confident80.8Confident3 Ų332.8 Ų32.82%0.01818%0.179CC..Hα-helixtrans-63.4-41.5174.4175.40000112L162 E165 L166 M169 Y557 Q559 M565L162-V561 HydrophobicContact CB-CG2 4.32Å; L162-V561 HydrophobicContact CD2-CG2 3.9Å; E165-V561 HydrophobicContact CB-CG2 4.45Å; L166-V561 HydrophobicContact CB-CG1 3.9Å; L166-V561 HydrophobicContact CB-CG2 4.46Å; L166-V561 HydrophobicContact CD1-CG1 3.73Å; L166-V561 HydrophobicContact CG-CG1 4.43Å; M169-V561 HydrophobicContact CE-CG1 4.09Å; M169-V561 HydrophobicContact SD-CB 3.91Å; M169-V561 HydrophobicContact SD-CG1 3.56Å; M169-V561 VanDerWaalsContact SD-CG1 3.56Å; Y557-V561 WeakPolarHBondContact O-CG2 3.28Å; Y557-V561 PolarHBondContact O-N 2.83Å; Q559-V561 VanDerWaalsContact C-N 3.33Å; Q559-V561 PolarHBondContact O-N 3.45Å; V561-M565 HydrophobicContact CG1-CG 4.44Å; V561-M565 HydrophobicContact CG1-SD 4.16Å; V561-M565 WeakPolarHBondContact O-CB 3.29Å; V561-M565 VanDerWaalsContact O-CG 3.26Å; V561-M565 WeakPolarHBondContact O-CG 3.34Å; V561-M565 PolarHBondContact O-N 3.1Å
562I91.1Very high79.9Confident2 Ų239.4 Ų39.41%0.0121%0.209CC..Hα-helixtrans-59.7-48.5173.8-70.5164.8000110.7M169 W211 A289 M291 R558 Q559 M565 Q566M169-I562 HydrophobicContact CE-CG1 3.61Å; M169-I562 HydrophobicContact SD-CG1 4.1Å; W211-I562 HydrophobicContact CZ2-CG2 4.39Å; A289-I562 HydrophobicContact CB-CG2 3.82Å; M291-I562 HydrophobicContact SD-CD1 4.33Å; R558-I562 VanDerWaalsContact O-CG1 3.3Å; R558-I562 WeakPolarHBondContact O-CG1 3.27Å; R558-I562 PolarHBondContact O-N 3.37Å; R558-I562 VanDerWaalsContact O-N 3.1Å; Q559-I562 WeakPolarHBondContact O-CB 3.41Å; Q559-I562 PolarHBondContact O-N 2.94Å; Q559-I562 VanDerWaalsContact O-N 3.15Å; I562-M565 PolarHBondContact O-N 2.97Å; I562-Q566 WeakPolarHBondContact O-CG 3.29Å; I562-Q566 PolarHBondContact O-N 3.32Å
563D90Very high79.2Confident15 Ų1541.4 Ų41.48%0.0822%0.224CC..Hα-helixtrans-62.2-45.3-178.1-70.9-13.2000110.9R295 Q559 A560 M565 Q566 G567 I568 V570R295-D563 IonicContact CZ-OD1 2.74Å; R295-D563 IonicContact CZ-OD2 2.87Å; R295-D563 IonicContact NE-OD1 3.22Å; R295-D563 IonicContact NH2-OD1 2.61Å; R295-D563 PolarHBondContact NH2-OD1 3.33Å; R295-D563 IonicContact NH2-OD2 2.63Å; R295-D563 PolarHBondContact NH2-OD2 3.25Å; Q559-D563 PolarHBondContact NE2-OD1 2.85Å; Q559-D563 WeakPolarHBondContact O-CB 3.48Å; Q559-D563 VanDerWaalsContact O-CG 3.28Å; Q559-D563 PolarHBondContact O-N 3.02Å; A560-D563 PolarHBondContact O-N 3.37Å; D563-M565 PolarHBondContact O-N 2.79Å; D563-Q566 CarbonylContact O-C 3.55Å; D563-Q566 PolarHBondContact O-N 3.26Å; D563-Q566 VanDerWaalsContact O-N 3.08Å; D563-G567 PolarHBondContact O-N 3.15Å; D563-G567 VanDerWaalsContact O-N 3.15Å; D563-I568 CarbonylContact C-O 3.57Å; D563-I568 HydrophobicContact CB-CB 3.97Å; D563-I568 HydrophobicContact CB-CG2 4.22Å; D563-I568 WeakPolarHBondContact O-CB 3.34Å; D563-I568 PolarHBondContact O-N 2.87Å; D563-V570 HydrophobicContact CB-CG2 3.71Å
564L89.1Confident78.7Confident16 Ų1637 Ų378%0.08421%0.205CC..Hα-helixtrans-61.7-42.1174.9-68.5168.4000112.9I55 L57 L162 A560 Q566 G567 V570I55-L564 HydrophobicContact CD1-CB 3.79Å; I55-L564 HydrophobicContact CG1-CB 4.18Å; L57-L564 HydrophobicContact CD2-CD1 3.77Å; L162-L564 HydrophobicContact CD1-CD1 4.22Å; A560-L564 WeakPolarHBondContact O-CB 3.46Å; A560-L564 WeakPolarHBondContact O-CG 3.45Å; A560-L564 PolarHBondContact O-N 2.79Å; L564-Q566 PolarHBondContact O-N 3.24Å; L564-G567 PolarHBondContact O-N 2.69Å; L564-V570 HydrophobicContact CD2-CB 4.34Å; L564-V570 HydrophobicContact CD2-CG2 3.83Å; L564-V570 HydrophobicContact CG-CG2 3.68Å
565M90.9Very high77.7Confident0 Ų038.6 Ų38.60%021%0.21CC..Hα-helixtrans-63.3-22.4175.2-73.8178.275.700112.8I55 L166 M169 F170 F176 M215 V561 I562 D563I55-M565 HydrophobicContact CD1-CG 3.87Å; L166-M565 HydrophobicContact CD1-SD 4.05Å; M169-M565 HydrophobicContact CE-SD 3.69Å; F170-M565 HydrophobicContact CE2-CE 3.68Å; F170-M565 HydrophobicContact CE2-SD 4.27Å; F170-M565 HydrophobicContact CZ-CE 3.59Å; F176-M565 HydrophobicContact CE1-CE 4.28Å; F176-M565 HydrophobicContact CZ-CE 3.91Å; M215-M565 HydrophobicContact CE-CE 4.27Å; M215-M565 HydrophobicContact CE-CG 4.37Å; M215-M565 WeakPolarHBondContact CG-O 3.31Å; M215-M565 HydrophobicContact SD-CB 4Å; M215-M565 HydrophobicContact SD-CE 3.57Å; M215-M565 VanDerWaalsContact SD-CE 3.57Å; M215-M565 HydrophobicContact SD-CG 3.92Å; V561-M565 HydrophobicContact CG1-CG 4.44Å; V561-M565 HydrophobicContact CG1-SD 4.16Å; V561-M565 WeakPolarHBondContact O-CB 3.29Å; V561-M565 VanDerWaalsContact O-CG 3.26Å; V561-M565 WeakPolarHBondContact O-CG 3.34Å; V561-M565 PolarHBondContact O-N 3.1Å; I562-M565 PolarHBondContact O-N 2.97Å; D563-M565 PolarHBondContact O-N 2.79Å
566Q90.5Very high76.4Confident17 Ų1739.4 Ų39.48%0.07922%0.216CC..THydrogen-bonded Turntrans-100.74.1178.5-59.8-50.8-23.400114.3W211 I562 D563 L564 I568W211-Q566 VanDerWaalsContact NE1-NE2 3.16Å; W211-Q566 PolarHBondContact O-NE2 3.14Å; W211-Q566 PolarHBondContact O-OE1 3.32Å; I562-Q566 WeakPolarHBondContact O-CG 3.29Å; I562-Q566 PolarHBondContact O-N 3.32Å; D563-Q566 CarbonylContact O-C 3.55Å; D563-Q566 PolarHBondContact O-N 3.26Å; D563-Q566 VanDerWaalsContact O-N 3.08Å; L564-Q566 PolarHBondContact O-N 3.24Å; Q566-I568 HydrophobicContact CB-CD1 4.43Å; Q566-I568 HydrophobicContact CB-CG1 4.39Å; Q566-I568 PolarHBondContact O-N 3.09Å
567G87.1Confident75.1Confident26 Ų2640.8 Ų40.827%0.26822%0.221SC..THydrogen-bonded Turntrans74.513.7-179.600000114.4D563 L564 P569D563-G567 PolarHBondContact O-N 3.15Å; D563-G567 VanDerWaalsContact O-N 3.15Å; L564-G567 PolarHBondContact O-N 2.69Å; G567-P569 WeakPolarHBondContact O-CD 3.47Å
568I84.7Confident73.7Confident72 Ų7242.3 Ų42.337%0.36923%0.228SC..  trans-78.9116.4172.7-59.1173.6000106.7D563 Q566 V570D563-I568 CarbonylContact C-O 3.57Å; D563-I568 HydrophobicContact CB-CB 3.97Å; D563-I568 HydrophobicContact CB-CG2 4.22Å; D563-I568 WeakPolarHBondContact O-CB 3.34Å; D563-I568 PolarHBondContact O-N 2.87Å; Q566-I568 HydrophobicContact CB-CD1 4.43Å; Q566-I568 HydrophobicContact CB-CG1 4.39Å; Q566-I568 PolarHBondContact O-N 3.09Å; I568-V570 PolarHBondContact O-N 3.1Å; I568-V570 VanDerWaalsContact O-N 3.14Å
569P71.6Confident72Confident98 Ų9844.6 Ų44.664%0.63624%0.244SC*.  trans-64.4119.5-179.526.2-33.7000109.1G567 T571G567-P569 WeakPolarHBondContact O-CD 3.47Å; P569-T571 VanDerWaalsContact C-N 3.31Å; P569-T571 PolarHBondContact O-N 2.87Å
570V66.9Low70.3Confident41 Ų4148.6 Ų48.625%0.24826%0.262CS..  trans-81.488.1177.1-169.80000108.2A560 D563 L564 I568 L574A560-V570 HydrophobicContact CB-CG1 4.05Å; A560-V570 HydrophobicContact CB-CG2 4.34Å; D563-V570 HydrophobicContact CB-CG2 3.71Å; L564-V570 HydrophobicContact CD2-CB 4.34Å; L564-V570 HydrophobicContact CD2-CG2 3.83Å; L564-V570 HydrophobicContact CG-CG2 3.68Å; I568-V570 PolarHBondContact O-N 3.1Å; I568-V570 VanDerWaalsContact O-N 3.14Å; V570-L574 HydrophobicContact CB-CD1 4.06Å; V570-L574 HydrophobicContact CG1-CB 4.12Å; V570-L574 HydrophobicContact CG1-CD1 3.47Å; V570-L574 VanDerWaalsContact CG1-CD1 3.47Å; V570-L574 HydrophobicContact CG1-CG 3.51Å
571T56.2Low68.7Low98 Ų9851.6 Ų51.660%0.60128%0.275SS*.  trans-64.1-172.2179.651.20000112.3P569 D573 L574P569-T571 VanDerWaalsContact C-N 3.31Å; P569-T571 PolarHBondContact O-N 2.87Å; T571-D573 PolarHBondContact O-N 3.17Å; T571-L574 PolarHBondContact O-N 3.44Å; T571-L574 VanDerWaalsContact O-N 3.15Å
572E50.7Low66.9Low162 Ų16258.1 Ų58.176%0.75730%0.303SS*.THydrogen-bonded Turntrans-51.8-13.5-169.1-58.8-171.3131.200116.1L574 Y575 S576E572-L574 PolarHBondContact O-N 3.18Å; E572-Y575 CarbonylContact O-C 3.57Å; E572-Y575 WeakPolarHBondContact O-CA 3.41Å; E572-Y575 WeakPolarHBondContact O-CB 3.45Å; E572-Y575 PolarHBondContact O-N 3.21Å; E572-S576 PolarHBondContact O-N 3.16Å
573D53Low65.1Low98 Ų9863.4 Ų63.452%0.52433%0.328SS..Hα-helixtrans-56.4-26.8172.1-108.5-24.5000114.1T571 S576 I577 K580T571-D573 PolarHBondContact O-N 3.17Å; D573-S576 CarbonylContact O-C 3.52Å; D573-S576 PolarHBondContact O-N 2.88Å; D573-S576 PolarHBondContact O-OG 3.09Å; D573-S576 PolarHBondContact OD1-OG 2.87Å; D573-I577 WeakPolarHBondContact O-CB 3.41Å; D573-I577 VanDerWaalsContact O-CD1 3.3Å; D573-I577 WeakPolarHBondContact O-CD1 3.34Å; D573-I577 WeakPolarHBondContact O-CG1 3.36Å; D573-I577 PolarHBondContact O-N 3.16Å; D573-K580 IonicContact OD1-NZ 3.73Å
574L56.9Low63.2Low8 Ų865.9 Ų65.94%0.04234%0.339CS..Hα-helixtrans-65.9-38.7170.6-104.4179.5000112.8L158 L162 A560 V570 T571 E572 I577 F578L158-L574 HydrophobicContact CD1-CD1 4.29Å; L158-L574 HydrophobicContact CD1-CD2 3.8Å; L158-L574 HydrophobicContact CD2-CD1 4.3Å; L162-L574 HydrophobicContact CD1-CD1 4.22Å; A560-L574 HydrophobicContact CB-CD1 4Å; A560-L574 HydrophobicContact CB-CD2 4.05Å; A560-L574 HydrophobicContact CB-CG 4.09Å; V570-L574 HydrophobicContact CB-CD1 4.06Å; V570-L574 HydrophobicContact CG1-CB 4.12Å; V570-L574 HydrophobicContact CG1-CD1 3.47Å; V570-L574 VanDerWaalsContact CG1-CD1 3.47Å; V570-L574 HydrophobicContact CG1-CG 3.51Å; T571-L574 PolarHBondContact O-N 3.44Å; T571-L574 VanDerWaalsContact O-N 3.15Å; E572-L574 PolarHBondContact O-N 3.18Å; L574-I577 HydrophobicContact CD2-CD1 4.31Å; L574-F578 VanDerWaalsContact O-CD2 3.32Å; L574-F578 WeakPolarHBondContact O-CD2 3.37Å
575Y53.6Low61.6Low89 Ų8970.7 Ų70.735%0.34936%0.361SS..Hα-helixtrans-71.6-40171.5-65.6-78.5000110.4H58 K155 E572 I577 F578 T579H58-Y575 PolarHBondContact CD2-OH 3.34Å; H58-Y575 VanDerWaalsContact CD2-OH 3.32Å; H58-Y575 AromaticContact NE2-CE2 3.86Å; H58-Y575 AromaticContact NE2-CZ 3.83Å; H58-Y575 PolarHBondContact NE2-OH 3.38Å; K155-Y575 WeakPolarHBondContact CE-OH 3.23Å; E572-Y575 CarbonylContact O-C 3.57Å; E572-Y575 WeakPolarHBondContact O-CA 3.41Å; E572-Y575 WeakPolarHBondContact O-CB 3.45Å; E572-Y575 PolarHBondContact O-N 3.21Å; Y575-I577 PolarHBondContact O-N 3.26Å; Y575-F578 WeakPolarHBondContact O-CB 3.44Å; Y575-F578 PolarHBondContact O-N 3.17Å; Y575-T579 PolarHBondContact O-N 2.79Å; Y575-T579 PolarHBondContact O-OG1 3.47Å
576S54.6Low59.9Low22 Ų2273.4 Ų73.415%0.15438%0.383CS..Hα-helixtrans-59.7-32.6175.5110.90000112.4E572 D573 T579 K580E572-S576 PolarHBondContact O-N 3.16Å; D573-S576 CarbonylContact O-C 3.52Å; D573-S576 PolarHBondContact O-N 2.88Å; D573-S576 PolarHBondContact O-OG 3.09Å; D573-S576 PolarHBondContact OD1-OG 2.87Å; S576-T579 PolarHBondContact O-N 3.15Å; S576-K580 VanDerWaalsContact O-CB 3.24Å; S576-K580 WeakPolarHBondContact O-CB 3.25Å; S576-K580 WeakPolarHBondContact O-CD 3.46Å; S576-K580 WeakPolarHBondContact O-CG 3.28Å; S576-K580 PolarHBondContact O-N 3.42Å; S576-K580 WeakPolarHBondContact OG-CE 3.47Å; S576-K580 PolarHBondContact OG-NZ 3.14Å
577I54.6Low58.2Low41 Ų4177 Ų7721%0.2140%0.402CS..Hα-helixtrans-61.9-42.1171.6-76.1154.6000111.3A556 D573 L574 Y575 E581A556-I577 HydrophobicContact CB-CD1 3.78Å; A556-I577 HydrophobicContact CB-CG1 4.23Å; A556-I577 HydrophobicContact CB-CG2 4.32Å; D573-I577 WeakPolarHBondContact O-CB 3.41Å; D573-I577 VanDerWaalsContact O-CD1 3.3Å; D573-I577 WeakPolarHBondContact O-CD1 3.34Å; D573-I577 WeakPolarHBondContact O-CG1 3.36Å; D573-I577 PolarHBondContact O-N 3.16Å; L574-I577 HydrophobicContact CD2-CD1 4.31Å; Y575-I577 PolarHBondContact O-N 3.26Å; I577-E581 WeakPolarHBondContact O-CB 3.35Å; I577-E581 PolarHBondContact O-N 2.95Å
578F53.9Low56.4Low43 Ų4380.5 Ų80.519%0.18941%0.411CS..Hα-helixtrans-68.8-40.8173.7-73.7-77.7000112.5L158 Y557 L574 Y575 E581 K582L158-F578 HydrophobicContact CB-CE2 3.84Å; L158-F578 HydrophobicContact CB-CZ 3.85Å; L158-F578 HydrophobicContact CD1-CE2 3.82Å; L158-F578 HydrophobicContact CD1-CZ 4.11Å; L158-F578 HydrophobicContact CD2-CE2 4.13Å; L158-F578 HydrophobicContact CG-CE2 4.12Å; L158-F578 HydrophobicContact CG-CZ 4.46Å; Y557-F578 HydrophobicContact CE1-CZ 4.43Å; L574-F578 VanDerWaalsContact O-CD2 3.32Å; L574-F578 WeakPolarHBondContact O-CD2 3.37Å; Y575-F578 WeakPolarHBondContact O-CB 3.44Å; Y575-F578 PolarHBondContact O-N 3.17Å; F578-E581 PolarHBondContact O-N 2.93Å; F578-K582 VanDerWaalsContact O-CB 3.26Å; F578-K582 WeakPolarHBondContact O-CB 3.32Å; F578-K582 PolarHBondContact O-N 3.35Å
579T51.6Low55.1Low70 Ų7082 Ų8243%0.42942%0.415SS..Hα-helixtrans-61.2-48.4177.5-35.50000110Y575 S576 K582 E583Y575-T579 PolarHBondContact O-N 2.79Å; Y575-T579 PolarHBondContact O-OG1 3.47Å; S576-T579 PolarHBondContact O-N 3.15Å; T579-K582 PolarHBondContact O-N 2.95Å; T579-E583 VanDerWaalsContact CG2-OE1 3.25Å; T579-E583 WeakPolarHBondContact CG2-OE1 3.42Å; T579-E583 WeakPolarHBondContact O-CB 3.23Å; T579-E583 VanDerWaalsContact O-CG 3.23Å; T579-E583 WeakPolarHBondContact O-CG 3.42Å; T579-E583 PolarHBondContact O-N 3.44Å
580K52.3Low54.2Low96 Ų9683.1 Ų83.142%0.41741%0.412SS..Hα-helixtrans-69-35.9178.8-66.9161.5-172.4162.70113.2D573 S576 K582 H584D573-K580 IonicContact OD1-NZ 3.73Å; S576-K580 VanDerWaalsContact O-CB 3.24Å; S576-K580 WeakPolarHBondContact O-CB 3.25Å; S576-K580 WeakPolarHBondContact O-CD 3.46Å; S576-K580 WeakPolarHBondContact O-CG 3.28Å; S576-K580 PolarHBondContact O-N 3.42Å; S576-K580 WeakPolarHBondContact OG-CE 3.47Å; S576-K580 PolarHBondContact OG-NZ 3.14Å; K580-K582 VanDerWaalsContact C-N 3.28Å; K580-K582 PolarHBondContact O-N 3.05Å; K580-H584 WeakPolarHBondContact O-CB 3.5Å; K580-H584 PolarHBondContact O-N 3.38Å
581E53.2Low53.7Low66 Ų6685.5 Ų85.531%0.30842%0.423SS..Hα-helixtrans-58.4-42.7171.3178.4169.7-116.100110.1R161 I577 F578 E585R161-E581 IonicContact CZ-OE2 3.27Å; R161-E581 IonicContact NH1-OE1 2.77Å; R161-E581 IonicContact NH1-OE2 2.64Å; R161-E581 PolarHBondContact NH1-OE2 2.83Å; R161-E581 IonicContact NH2-OE1 3.33Å; R161-E581 IonicContact NH2-OE2 2.83Å; I577-E581 WeakPolarHBondContact O-CB 3.35Å; I577-E581 PolarHBondContact O-N 2.95Å; F578-E581 PolarHBondContact O-N 2.93Å; E581-E585 WeakPolarHBondContact O-CB 3.41Å; E581-E585 PolarHBondContact O-N 3.11Å
582K51.7Low53.5Low141 Ų14186.1 Ų86.161%0.61342%0.42SS*.Hα-helixtrans-78.5-40-178.1-174.5-176.6175.4-165.60113.8F578 T579 K580 E585 A586F578-K582 VanDerWaalsContact O-CB 3.26Å; F578-K582 WeakPolarHBondContact O-CB 3.32Å; F578-K582 PolarHBondContact O-N 3.35Å; T579-K582 PolarHBondContact O-N 2.95Å; K580-K582 VanDerWaalsContact C-N 3.28Å; K580-K582 PolarHBondContact O-N 3.05Å; K582-E585 PolarHBondContact O-N 2.95Å; K582-A586 PolarHBondContact O-N 3.47Å
583E55Low54Low112 Ų11286.9 Ų86.952%0.52342%0.416SS..Hα-helixtrans-60.8-46171.3-74.2161.3179.800110.5T579 E585 A586 L587T579-E583 VanDerWaalsContact CG2-OE1 3.25Å; T579-E583 WeakPolarHBondContact CG2-OE1 3.42Å; T579-E583 WeakPolarHBondContact O-CB 3.23Å; T579-E583 VanDerWaalsContact O-CG 3.23Å; T579-E583 WeakPolarHBondContact O-CG 3.42Å; T579-E583 PolarHBondContact O-N 3.44Å; E583-E585 VanDerWaalsContact C-N 3.32Å; E583-E585 PolarHBondContact O-N 2.86Å; E583-A586 WeakPolarHBondContact O-CB 3.41Å; E583-A586 PolarHBondContact O-N 2.79Å; E583-L587 VanDerWaalsContact O-CB 3.3Å; E583-L587 WeakPolarHBondContact O-CB 3.48Å; E583-L587 PolarHBondContact O-N 2.84Å
584H50.1Low54.2Low68 Ų6884.9 Ų84.932%0.31541%0.409SS..Hα-helixtrans-66.3-32.9175.6-172.9-55.6000112K580 A586 H588K580-H584 WeakPolarHBondContact O-CB 3.5Å; K580-H584 PolarHBondContact O-N 3.38Å; H584-A586 VanDerWaalsContact C-N 3.33Å; H584-H588 WeakPolarHBondContact O-CB 3.4Å; H584-H588 PolarHBondContact O-N 3.18Å
585E54.1Low54Low117 Ų11789.4 Ų89.455%0.54743%0.43SS..Hα-helixtrans-68.6-31.6173.4-154-164-110.300112.3E581 K582 E583 K589E581-E585 WeakPolarHBondContact O-CB 3.41Å; E581-E585 PolarHBondContact O-N 3.11Å; K582-E585 PolarHBondContact O-N 2.95Å; E583-E585 VanDerWaalsContact C-N 3.32Å; E583-E585 PolarHBondContact O-N 2.86Å; E585-K589 VanDerWaalsContact O-CD 3.29Å; E585-K589 WeakPolarHBondContact O-CD 3.49Å; E585-K589 WeakPolarHBondContact O-CE 3.37Å; E585-K589 VanDerWaalsContact O-CG 3.28Å; E585-K589 WeakPolarHBondContact O-CG 3.26Å; E585-K589 PolarHBondContact O-N 3.44Å; E585-K589 IonicContact OE2-NZ 3.48Å; E585-K589 PolarHBondContact OE2-NZ 2.81Å
586A55.4Low54Low56 Ų5690.1 Ų90.146%0.46344%0.437SS..Hα-helixtrans-71.5-50.5170.700000111.6K582 E583 H584 H588 K589 E590K582-A586 PolarHBondContact O-N 3.47Å; E583-A586 WeakPolarHBondContact O-CB 3.41Å; E583-A586 PolarHBondContact O-N 2.79Å; H584-A586 VanDerWaalsContact C-N 3.33Å; A586-H588 VanDerWaalsContact C-N 3.26Å; A586-H588 PolarHBondContact O-N 3.06Å; A586-K589 CarbonylContact O-C 3.56Å; A586-K589 WeakPolarHBondContact O-CA 3.4Å; A586-K589 WeakPolarHBondContact O-CB 3.12Å; A586-K589 PolarHBondContact O-N 2.75Å; A586-E590 PolarHBondContact O-N 3.19Å
587L55.5Low54.5Low93 Ų9394.6 Ų94.649%0.48746%0.455SS..Hα-helixtrans-67.5-23.5-177.3-166.4146000112.8E583 N591E583-L587 VanDerWaalsContact O-CB 3.3Å; E583-L587 WeakPolarHBondContact O-CB 3.48Å; E583-L587 PolarHBondContact O-N 2.84Å; L587-N591 VanDerWaalsContact CD2-ND2 3.34Å; L587-N591 WeakPolarHBondContact CD2-ND2 3.18Å; L587-N591 WeakPolarHBondContact O-CB 3.46Å; L587-N591 PolarHBondContact O-N 2.91Å; L587-N591 PolarHBondContact O-ND2 3.4Å
588H49.8Very low54.8Low99 Ų9996.9 Ų96.946%0.45847%0.467SS..Hα-helixtrans-73.7-40168.1-168.5-72.4000112.2H584 A586 E590 Q592H584-H588 WeakPolarHBondContact O-CB 3.4Å; H584-H588 PolarHBondContact O-N 3.18Å; A586-H588 VanDerWaalsContact C-N 3.26Å; A586-H588 PolarHBondContact O-N 3.06Å; H588-E590 VanDerWaalsContact C-N 3.29Å; H588-Q592 PolarHBondContact CE1-OE1 2.88Å; H588-Q592 PolarHBondContact ND1-OE1 3.32Å; H588-Q592 WeakPolarHBondContact O-CB 3.29Å; H588-Q592 VanDerWaalsContact O-CG 3.32Å; H588-Q592 WeakPolarHBondContact O-CG 3.38Å; H588-Q592 PolarHBondContact O-N 3.21Å; H588-Q592 PolarHBondContact O-OE1 3.19Å
589K56.6Low55.1Low104 Ų10498.3 Ų98.345%0.45248%0.476SS..Hα-helixtrans-66.5-34.5173.5-68.7163.4-168.4162.30111.2E585 A586 Q592 R593E585-K589 VanDerWaalsContact O-CD 3.29Å; E585-K589 WeakPolarHBondContact O-CD 3.49Å; E585-K589 WeakPolarHBondContact O-CE 3.37Å; E585-K589 VanDerWaalsContact O-CG 3.28Å; E585-K589 WeakPolarHBondContact O-CG 3.26Å; E585-K589 PolarHBondContact O-N 3.44Å; E585-K589 IonicContact OE2-NZ 3.48Å; E585-K589 PolarHBondContact OE2-NZ 2.81Å; A586-K589 CarbonylContact O-C 3.56Å; A586-K589 WeakPolarHBondContact O-CA 3.4Å; A586-K589 WeakPolarHBondContact O-CB 3.12Å; A586-K589 PolarHBondContact O-N 2.75Å; K589-Q592 PolarHBondContact O-N 3.4Å; K589-R593 WeakPolarHBondContact O-CG 3.32Å; K589-R593 PolarHBondContact O-N 3.48Å
590E52.7Low55.3Low121 Ų12198.1 Ų98.157%0.56548%0.477SS*.Hα-helixtrans-67.2-50.1173.5-173170.3-14400112.1A586 H588 Q592 R593 S594A586-E590 PolarHBondContact O-N 3.19Å; H588-E590 VanDerWaalsContact C-N 3.29Å; E590-Q592 PolarHBondContact O-N 2.92Å; E590-R593 WeakPolarHBondContact O-CA 3.41Å; E590-R593 WeakPolarHBondContact O-CB 3.47Å; E590-R593 PolarHBondContact O-N 3.21Å; E590-S594 PolarHBondContact O-N 2.91Å; E590-S594 PolarHBondContact O-OG 3.45Å
591N56Low55.8Low91 Ų9199.7 Ų99.749%0.48749%0.486SS..Hα-helixtrans-61.1-30.2172.8-88.7-75000113.2L587 S594 H595L587-N591 VanDerWaalsContact CD2-ND2 3.34Å; L587-N591 WeakPolarHBondContact CD2-ND2 3.18Å; L587-N591 WeakPolarHBondContact O-CB 3.46Å; L587-N591 PolarHBondContact O-N 2.91Å; L587-N591 PolarHBondContact O-ND2 3.4Å; N591-S594 PolarHBondContact O-OG 3.48Å; N591-H595 WeakPolarHBondContact O-CB 3.28Å; N591-H595 PolarHBondContact O-N 3.42Å
592Q51.8Low56.1Low112 Ų112101.8 Ų101.852%0.52350%0.499SS..Hα-helixtrans-69.5-36.5171.8-76.6178-71.600111.9H588 K589 E590 Q596H588-Q592 PolarHBondContact CE1-OE1 2.88Å; H588-Q592 PolarHBondContact ND1-OE1 3.32Å; H588-Q592 WeakPolarHBondContact O-CB 3.29Å; H588-Q592 VanDerWaalsContact O-CG 3.32Å; H588-Q592 WeakPolarHBondContact O-CG 3.38Å; H588-Q592 PolarHBondContact O-N 3.21Å; H588-Q592 PolarHBondContact O-OE1 3.19Å; K589-Q592 PolarHBondContact O-N 3.4Å; E590-Q592 PolarHBondContact O-N 2.92Å; Q592-Q596 VanDerWaalsContact O-CB 3.3Å; Q592-Q596 WeakPolarHBondContact O-CB 3.42Å; Q592-Q596 PolarHBondContact O-N 3.36Å
593R62Low56.2Low178 Ų17898.2 Ų98.267%0.67249%0.486SS*.Hα-helixtrans-67.1-52.3174-72.8169.1177-174-3.8112K589 E590 H595 Q596 E597K589-R593 WeakPolarHBondContact O-CG 3.32Å; K589-R593 PolarHBondContact O-N 3.48Å; E590-R593 WeakPolarHBondContact O-CA 3.41Å; E590-R593 WeakPolarHBondContact O-CB 3.47Å; E590-R593 PolarHBondContact O-N 3.21Å; R593-H595 VanDerWaalsContact C-N 3.28Å; R593-H595 PolarHBondContact O-N 3.1Å; R593-Q596 CarbonylContact O-C 3.56Å; R593-Q596 WeakPolarHBondContact O-CA 3.46Å; R593-Q596 WeakPolarHBondContact O-CB 3.41Å; R593-Q596 PolarHBondContact O-N 3.35Å; R593-E597 WeakPolarHBondContact O-CG 3.29Å; R593-E597 PolarHBondContact O-N 3.42Å
594S57.1Low56.4Low56 Ų56100 Ų10039%0.39249%0.494SS..Hα-helixtrans-64.2-32.7-179.763.30000112.6E590 N591 L598E590-S594 PolarHBondContact O-N 2.91Å; E590-S594 PolarHBondContact O-OG 3.45Å; N591-S594 PolarHBondContact O-OG 3.48Å; S594-L598 WeakPolarHBondContact O-CB 3.14Å; S594-L598 PolarHBondContact O-N 2.98Å
595H52.3Low57.2Low102 Ų10299.9 Ų99.947%0.47250%0.501SS..Hα-helixtrans-69.1-38.6171.4-16832.3000112.3N591 R593 I599N591-H595 WeakPolarHBondContact O-CB 3.28Å; N591-H595 PolarHBondContact O-N 3.42Å; R593-H595 VanDerWaalsContact C-N 3.28Å; R593-H595 PolarHBondContact O-N 3.1Å; H595-I599 WeakPolarHBondContact O-CB 3.05Å; H595-I599 WeakPolarHBondContact O-CD1 3.26Å; H595-I599 VanDerWaalsContact O-CG1 3.22Å; H595-I599 WeakPolarHBondContact O-CG1 3.45Å; H595-I599 PolarHBondContact O-N 2.73Å
596Q53.1Low57.7Low105 Ų105100.8 Ų100.849%0.49150%0.501SS..Hα-helixtrans-64.3-42.6174.3-164.175.134.900111.2Q592 R593 I599 S600Q592-Q596 VanDerWaalsContact O-CB 3.3Å; Q592-Q596 WeakPolarHBondContact O-CB 3.42Å; Q592-Q596 PolarHBondContact O-N 3.36Å; R593-Q596 CarbonylContact O-C 3.56Å; R593-Q596 WeakPolarHBondContact O-CA 3.46Å; R593-Q596 WeakPolarHBondContact O-CB 3.41Å; R593-Q596 PolarHBondContact O-N 3.35Å; Q596-I599 PolarHBondContact O-N 2.91Å; Q596-S600 PolarHBondContact O-N 3.47Å; Q596-S600 PolarHBondContact O-OG 3.1Å; Q596-S600 VanDerWaalsContact O-OG 3.13Å
597E64.9Low57.6Low115 Ų115101.9 Ų101.954%0.53750%0.497SS..Hα-helixtrans-64.1-44.4176.7-72.2160.8-17400111.8R593 I599 S600 Q601R593-E597 WeakPolarHBondContact O-CG 3.29Å; R593-E597 PolarHBondContact O-N 3.42Å; E597-I599 VanDerWaalsContact C-N 3.34Å; E597-I599 PolarHBondContact O-N 3.05Å; E597-S600 WeakPolarHBondContact O-CB 3.06Å; E597-S600 PolarHBondContact O-N 2.94Å; E597-Q601 WeakPolarHBondContact O-CG 3.18Å; E597-Q601 PolarHBondContact O-N 3.46Å
598L61.3Low58Low89 Ų89104 Ų10447%0.46650%0.502SS..Hα-helixtrans-62.5-39.7174179.863.2000112.1S594 Q601 L602S594-L598 WeakPolarHBondContact O-CB 3.14Å; S594-L598 PolarHBondContact O-N 2.98Å; L598-Q601 PolarHBondContact O-N 3.14Å; L598-L602 HydrophobicContact CD1-CD1 4.42Å; L598-L602 HydrophobicContact CG-CD1 4.24Å; L598-L602 WeakPolarHBondContact O-CB 3.15Å; L598-L602 WeakPolarHBondContact O-CG 3.43Å; L598-L602 PolarHBondContact O-N 3.27Å
599I60.2Low58.8Low74 Ų74105.8 Ų105.838%0.37952%0.515SS..Hα-helixtrans-62.5-44.9173.2-72.6164.5000110.1H595 Q596 E597 L602 L603H595-I599 WeakPolarHBondContact O-CB 3.05Å; H595-I599 WeakPolarHBondContact O-CD1 3.26Å; H595-I599 VanDerWaalsContact O-CG1 3.22Å; H595-I599 WeakPolarHBondContact O-CG1 3.45Å; H595-I599 PolarHBondContact O-N 2.73Å; Q596-I599 PolarHBondContact O-N 2.91Å; E597-I599 VanDerWaalsContact C-N 3.34Å; E597-I599 PolarHBondContact O-N 3.05Å; I599-L602 PolarHBondContact O-N 3.46Å; I599-L603 WeakPolarHBondContact O-CB 3.49Å; I599-L603 PolarHBondContact O-N 2.85Å
600S55.2Low59.2Low65 Ų65103.1 Ų103.146%0.45551%0.505SS..Hα-helixtrans-61.5-43.6177.1-66.50000112.8Q596 E597 L603 Q604Q596-S600 PolarHBondContact O-N 3.47Å; Q596-S600 PolarHBondContact O-OG 3.1Å; Q596-S600 VanDerWaalsContact O-OG 3.13Å; E597-S600 WeakPolarHBondContact O-CB 3.06Å; E597-S600 PolarHBondContact O-N 2.94Å; S600-L603 PolarHBondContact O-N 2.94Å; S600-Q604 WeakPolarHBondContact O-CB 3.24Å; S600-Q604 PolarHBondContact O-N 3.28Å
601Q63.1Low60.1Low129 Ų12998.2 Ų98.260%0.60348%0.483SS*.Hα-helixtrans-64-42175.9-72.6177.6-200112.2E597 L598 Q604 S605E597-Q601 WeakPolarHBondContact O-CG 3.18Å; E597-Q601 PolarHBondContact O-N 3.46Å; L598-Q601 PolarHBondContact O-N 3.14Å; Q601-Q604 PolarHBondContact O-N 3.05Å; Q601-S605 VanDerWaalsContact O-CB 3.29Å; Q601-S605 WeakPolarHBondContact O-CB 3.44Å; Q601-S605 PolarHBondContact O-N 3.29Å
602L60.1Low61.2Low110 Ų11096.3 Ų96.358%0.57648%0.476SS*.Hα-helixtrans-63.7-41.3174.8-80166.9000111.9L598 I599 S605 Y606L598-L602 HydrophobicContact CD1-CD1 4.42Å; L598-L602 HydrophobicContact CG-CD1 4.24Å; L598-L602 WeakPolarHBondContact O-CB 3.15Å; L598-L602 WeakPolarHBondContact O-CG 3.43Å; L598-L602 PolarHBondContact O-N 3.27Å; I599-L602 PolarHBondContact O-N 3.46Å; L602-S605 PolarHBondContact O-N 2.93Å; L602-Y606 VanDerWaalsContact O-CB 3.25Å; L602-Y606 WeakPolarHBondContact O-CB 3.39Å; L602-Y606 PolarHBondContact O-N 3.42Å
603L54.3Low62.3Low67 Ų6797.3 Ų97.335%0.35149%0.485SS..Hα-helixtrans-64.7-46177.6-133.3170.3000111I599 S600 S605 Y606 M607 V1082I599-L603 WeakPolarHBondContact O-CB 3.49Å; I599-L603 PolarHBondContact O-N 2.85Å; S600-L603 PolarHBondContact O-N 2.94Å; L603-S605 PolarHBondContact O-N 3.14Å; L603-Y606 PolarHBondContact O-N 3.45Å; L603-M607 HydrophobicContact CD2-CG 3.91Å; L603-M607 HydrophobicContact CD2-SD 3.77Å; L603-M607 WeakPolarHBondContact O-CG 3.34Å; L603-M607 PolarHBondContact O-N 3.42Å; L603-V1082 HydrophobicContact CD1-CG2 3.95Å
604Q59Low63.1Low148 Ų14894.7 Ų94.769%0.69248%0.484SS*.Hα-helixtrans-64-40.3178.3-169.8174.39.700112.1S600 Q601 K608S600-Q604 WeakPolarHBondContact O-CB 3.24Å; S600-Q604 PolarHBondContact O-N 3.28Å; Q601-Q604 PolarHBondContact O-N 3.05Å; Q604-K608 PolarHBondContact O-N 3.41Å
605S67.7Low64.4Low66 Ų6692.7 Ų92.746%0.46247%0.468SS..Hα-helixtrans-65.6-43.6173.8-174.20000112.1Q601 L602 L603 K608 L609Q601-S605 VanDerWaalsContact O-CB 3.29Å; Q601-S605 WeakPolarHBondContact O-CB 3.44Å; Q601-S605 PolarHBondContact O-N 3.29Å; L602-S605 PolarHBondContact O-N 2.93Å; L603-S605 PolarHBondContact O-N 3.14Å; S605-K608 PolarHBondContact O-N 3.05Å; S605-L609 WeakPolarHBondContact O-CG 3.3Å; S605-L609 PolarHBondContact O-N 3.11Å
606Y62.8Low65.8Low137 Ų13795.1 Ų95.154%0.53748%0.477SS..Hα-helixtrans-65.4-43.5178.5-176.2-107.6000112.4L602 L603 K608 L609 L610L602-Y606 VanDerWaalsContact O-CB 3.25Å; L602-Y606 WeakPolarHBondContact O-CB 3.39Å; L602-Y606 PolarHBondContact O-N 3.42Å; L603-Y606 PolarHBondContact O-N 3.45Å; Y606-K608 PolarHBondContact O-N 2.68Å; Y606-L609 PolarHBondContact O-N 3.39Å; Y606-L610 HydrophobicContact CE1-CD2 3.92Å; Y606-L610 WeakPolarHBondContact O-CB 3.4Å; Y606-L610 PolarHBondContact O-N 2.81Å
607M55.2Low67Low79 Ų7993.4 Ų93.439%0.38947%0.468SS..Hα-helixtrans-60.9-32175-70.9-177.577.300112.3L603 L609 F617L603-M607 HydrophobicContact CD2-CG 3.91Å; L603-M607 HydrophobicContact CD2-SD 3.77Å; L603-M607 WeakPolarHBondContact O-CG 3.34Å; L603-M607 PolarHBondContact O-N 3.42Å; M607-L609 VanDerWaalsContact C-N 3.32Å; M607-F617 HydrophobicContact CE-CB 3.64Å; M607-F617 HydrophobicContact CE-CD1 3.53Å; M607-F617 HydrophobicContact CE-CE1 4.35Å; M607-F617 HydrophobicContact CE-CG 3.72Å
608K62.6Low67.8Low136 Ų13692.1 Ų92.159%0.59146%0.462SS*.Hα-helixtrans-78.1-11.7174.7-145.9-148.4172.1-1550114.6Q604 S605 Y606 D613Q604-K608 PolarHBondContact O-N 3.41Å; S605-K608 PolarHBondContact O-N 3.05Å; Y606-K608 PolarHBondContact O-N 2.68Å; K608-D613 WeakPolarHBondContact CE-OD1 3.16Å; K608-D613 IonicContact NZ-OD1 3.13Å; K608-D613 PolarHBondContact NZ-OD1 3.02Å; K608-D613 IonicContact NZ-OD2 3.05Å
609L66.4Low68.6Low137 Ų13788.2 Ų88.272%0.71744%0.444SS*.Hα-helixtrans-102.3-14.5176.5-72.8167.4000112.7S605 Y606 M607S605-L609 WeakPolarHBondContact O-CG 3.3Å; S605-L609 PolarHBondContact O-N 3.11Å; Y606-L609 PolarHBondContact O-N 3.39Å; M607-L609 VanDerWaalsContact C-N 3.32Å
610L64.5Low69.6Low49 Ų4985.6 Ų85.626%0.25744%0.435SS..Hα-helixtrans-89.3-22.8-174.3-17062.1000113.3Y606 L643Y606-L610 HydrophobicContact CE1-CD2 3.92Å; Y606-L610 WeakPolarHBondContact O-CB 3.4Å; Y606-L610 PolarHBondContact O-N 2.81Å; L610-L643 HydrophobicContact CD1-CD1 4.05Å; L610-L643 HydrophobicContact CD2-CD1 3.82Å; L610-L643 HydrophobicContact CG-CD1 3.92Å
611L72.6Confident71.1Confident17 Ų1785.1 Ų85.19%0.08942%0.423CS..SBendtrans-128.2156.7179.9-64-180000110.5E615 F617 Y650L611-E615 HydrophobicContact CB-CB 4.13Å; L611-E615 HydrophobicContact CD1-CB 4.42Å; L611-F617 HydrophobicContact CD1-CB 3.69Å; L611-F617 HydrophobicContact CD1-CD2 4.39Å; L611-F617 VanDerWaalsContact CD1-N 3.32Å; L611-Y650 HydrophobicContact CD2-CD2 4.1Å; L611-Y650 HydrophobicContact CD2-CE1 4.42Å; L611-Y650 HydrophobicContact CD2-CE2 3.37Å
612P79.3Confident72Confident52 Ų5280.6 Ų80.634%0.33841%0.408SS..  trans-54.4152.1164.9-27.137.6000113.1D614 E615 Y650P612-D614 WeakPolarHBondContact CB-OD1 3.38Å; P612-D614 PolarHBondContact O-N 2.96Å; P612-D614 VanDerWaalsContact O-N 3.13Å; P612-E615 HydrophobicContact CB-CB 4.44Å; P612-E615 HydrophobicContact CB-CG 4.23Å; P612-E615 HydrophobicContact CG-CG 4.3Å; P612-E615 WeakPolarHBondContact CG-OE1 3.35Å; P612-E615 PolarHBondContact O-N 2.93Å; P612-Y650 WeakPolarHBondContact CD-OH 3.41Å
613D73.8Confident73.3Confident133 Ų13375.5 Ų75.571%0.71138%0.381SS*.THydrogen-bonded Turntrans-59.9-22.3-178.1-92.4-66.5000114K608K608-D613 WeakPolarHBondContact CE-OD1 3.16Å; K608-D613 IonicContact NZ-OD1 3.13Å; K608-D613 PolarHBondContact NZ-OD1 3.02Å; K608-D613 IonicContact NZ-OD2 3.05Å
614D80.4Confident74.8Confident122 Ų12272.5 Ų72.565%0.65237%0.366SS*.THydrogen-bonded Turntrans-89-11.5176.559.3-55.6000114.1P612P612-D614 WeakPolarHBondContact CB-OD1 3.38Å; P612-D614 PolarHBondContact O-N 2.96Å; P612-D614 VanDerWaalsContact O-N 3.13Å
615E82.9Confident76.1Confident14 Ų1466.3 Ų66.37%0.06534%0.337CS..  trans-99.4141.8-177.7-70.5-167.8-135.600113.3L611 P612 S645 N646 Y650 R666L611-E615 HydrophobicContact CB-CB 4.13Å; L611-E615 HydrophobicContact CD1-CB 4.42Å; P612-E615 HydrophobicContact CB-CB 4.44Å; P612-E615 HydrophobicContact CB-CG 4.23Å; P612-E615 HydrophobicContact CG-CG 4.3Å; P612-E615 WeakPolarHBondContact CG-OE1 3.35Å; P612-E615 PolarHBondContact O-N 2.93Å; E615-S645 WeakPolarHBondContact OE2-CB 3.45Å; E615-S645 PolarHBondContact OE2-OG 3.31Å; E615-N646 WeakPolarHBondContact CA-OD1 3.08Å; E615-Y650 VanDerWaalsContact CD-OH 3.25Å; E615-Y650 PolarHBondContact OE1-OH 3.49Å; E615-Y650 VanDerWaalsContact OE1-OH 3.12Å; E615-Y650 PolarHBondContact OE2-OH 3.09Å; E615-R666 IonicContact OE1-CZ 2.63Å; E615-R666 IonicContact OE1-NE 3.54Å; E615-R666 PolarHBondContact OE1-NE 2.82Å; E615-R666 IonicContact OE1-NH2 3.8Å; E615-R666 PolarHBondContact OE1-NH2 2.95Å
616K81.4Confident76.5Confident153 Ų15363.9 Ų63.967%0.66532%0.32SS*.  trans-115.6124.1179.4-68.4179.1-178.5172.10110.3H618 S645 N646K616-H618 PolarHBondContact O-CD2 3.38Å; K616-H618 PolarHBondContact O-N 2.91Å; K616-S645 CarbonylContact O-C 3.59Å; K616-S645 WeakPolarHBondContact O-CA 3.35Å; K616-S645 WeakPolarHBondContact O-CB 3.35Å; K616-N646 HydrophobicContact CB-CB 4.45Å; K616-N646 PolarHBondContact N-OD1 3.1Å; K616-N646 PolarHBondContact O-N 3.02Å
617F80Confident76.8Confident69 Ų6957.6 Ų57.630%0.30330%0.296SS..EExtended strand (participates in β ladder)trans-62.8125.9176.3-177.2-95.1000111.5M607 L611 G619 L643M607-F617 HydrophobicContact CE-CB 3.64Å; M607-F617 HydrophobicContact CE-CD1 3.53Å; M607-F617 HydrophobicContact CE-CE1 4.35Å; M607-F617 HydrophobicContact CE-CG 3.72Å; L611-F617 HydrophobicContact CD1-CB 3.69Å; L611-F617 HydrophobicContact CD1-CD2 4.39Å; L611-F617 VanDerWaalsContact CD1-N 3.32Å; F617-G619 WeakPolarHBondContact CE2-O 3.42Å; F617-G619 VanDerWaalsContact CZ-O 3.3Å; F617-G619 WeakPolarHBondContact CZ-O 3.3Å; F617-L643 HydrophobicContact CE2-CD2 4.26Å
618H81.1Confident77Confident88 Ų8856.5 Ų56.541%0.40730%0.295SS..EExtended strand (participates in β ladder)trans-106.9-41.5175.4-76.4-168.3000112K616 L644 T733K616-H618 PolarHBondContact O-CD2 3.38Å; K616-H618 PolarHBondContact O-N 2.91Å; H618-L644 HydrophobicContact CB-CD2 4.5Å; H618-L644 HydrophobicContact CB-CG 4.17Å; H618-L644 PolarHBondContact N-O 3.3Å; H618-T733 VanDerWaalsContact ND1-CG2 3.34Å; H618-T733 WeakPolarHBondContact ND1-CG2 3.46Å; H618-T733 PolarHBondContact ND1-OG1 3.32Å
619G77.9Confident76.6Confident8 Ų853.8 Ų53.88%0.08229%0.293CS..EExtended strand (participates in β ladder)trans-163.3165.1-175.700000113.7F617 L644F617-G619 WeakPolarHBondContact CE2-O 3.42Å; F617-G619 VanDerWaalsContact CZ-O 3.3Å; F617-G619 WeakPolarHBondContact CZ-O 3.3Å; G619-L644 PolarHBondContact N-O 3.16Å; G619-L644 PolarHBondContact O-N 3.32Å
620G82.3Confident75.9Confident19 Ų1952.3 Ų52.320%0.19629%0.285CS..EExtended strand (participates in β ladder)trans-166.4135.5177.800000112.8L642G620-L642 CarbonylContact C-O 3.56Å; G620-L642 VanDerWaalsContact CA-O 3.24Å; G620-L642 WeakPolarHBondContact CA-O 3.36Å
621W86.3Confident75.2Confident54 Ų5454.7 Ų54.721%0.20530%0.297CS..EExtended strand (participates in β ladder)trans-139.3137-168.6-53.6-91.8000111.3L623 L642 L644 I726 M729W621-L623 HydrophobicContact CB-CD2 4.48Å; W621-L623 HydrophobicContact CB-CG 4.28Å; W621-L642 HydrophobicContact CE3-CB 4.47Å; W621-L642 HydrophobicContact CE3-CD2 3.98Å; W621-L642 HydrophobicContact CE3-CG 4.05Å; W621-L642 HydrophobicContact CZ3-CD2 4.38Å; W621-L642 HydrophobicContact CZ3-CG 4.45Å; W621-L642 PolarHBondContact N-O 2.92Å; W621-L642 PolarHBondContact O-N 3.43Å; W621-L644 HydrophobicContact CH2-CB 4.16Å; W621-L644 HydrophobicContact CH2-CD2 4.02Å; W621-L644 HydrophobicContact CZ3-CB 3.85Å; W621-L644 HydrophobicContact CZ3-CD2 4.4Å; W621-I726 HydrophobicContact CB-CD1 4.08Å; W621-I726 HydrophobicContact CD2-CD1 4.16Å; W621-I726 HydrophobicContact CD2-CG1 3.85Å; W621-I726 HydrophobicContact CD2-CG2 4.35Å; W621-I726 HydrophobicContact CE3-CG2 4.24Å; W621-I726 HydrophobicContact CG-CD1 3.74Å; W621-I726 HydrophobicContact CG-CG1 3.89Å; W621-I726 HydrophobicContact CZ2-CG1 4.26Å; W621-I726 HydrophobicContact CZ3-CG2 4.34Å; W621-M729 HydrophobicContact CH2-CB 4.35Å; W621-M729 HydrophobicContact CH2-CG 4.33Å; W621-M729 HydrophobicContact CH2-SD 3.67Å; W621-M729 HydrophobicContact CZ2-CB 4.4Å; W621-M729 HydrophobicContact CZ2-CE 4.13Å; W621-M729 HydrophobicContact CZ2-CG 4.5Å; W621-M729 HydrophobicContact CZ2-SD 3.54Å; W621-M729 VanDerWaalsContact CZ2-SD 3.54Å
622A82.3Confident74Confident35 Ų3560.1 Ų60.129%0.28933%0.326SS..EExtended strand (participates in β ladder)trans-86.2124.1164.800000108.9
623L87.1Confident72.6Confident2 Ų262.9 Ų62.91%0.0135%0.354CS..EExtended strand (participates in β ladder)trans-128.5176.7-177.5-62.1176.1000108.5W621 V640 L642 M692 L708 R709 L723 I726W621-L623 HydrophobicContact CB-CD2 4.48Å; W621-L623 HydrophobicContact CB-CG 4.28Å; L623-V640 PolarHBondContact N-O 3.42Å; L623-V640 PolarHBondContact O-N 2.78Å; L623-L642 HydrophobicContact CD1-CB 3.91Å; L623-L642 HydrophobicContact CD1-CD2 3.8Å; L623-M692 HydrophobicContact CD1-CE 4.47Å; L623-L708 HydrophobicContact CB-CB 4.4Å; L623-L708 HydrophobicContact CD1-CB 4.08Å; L623-L708 HydrophobicContact CD1-CD1 3.81Å; L623-R709 CarbonylContact C-O 3.59Å; L623-R709 WeakPolarHBondContact CA-O 3.42Å; L623-R709 WeakPolarHBondContact CB-O 3.4Å; L623-L723 HydrophobicContact CD2-CD2 4.22Å; L623-I726 HydrophobicContact CD1-CD1 4.43Å; L623-I726 HydrophobicContact CD2-CD1 3.9Å
624I86.1Confident71.6Confident5 Ų560.6 Ų60.63%0.02634%0.344CS..EExtended strand (participates in β ladder)trans-126.1141.1173.4-74.4158.9000109.2D637 V638 L708 R709 V711I624-D637 HydrophobicContact CD1-CB 3.95Å; I624-D637 HydrophobicContact CG1-CB 4.21Å; I624-D637 HydrophobicContact CG2-CB 3.82Å; I624-V638 VanDerWaalsContact CA-O 3.31Å; I624-V638 WeakPolarHBondContact CA-O 3.39Å; I624-L708 CarbonylContact O-C 3.52Å; I624-L708 WeakPolarHBondContact O-CA 3.34Å; I624-R709 HydrophobicContact CB-CG 4.05Å; I624-R709 HydrophobicContact CG2-CG 4.36Å; I624-R709 PolarHBondContact N-O 3.27Å; I624-R709 PolarHBondContact O-N 2.88Å; I624-V711 HydrophobicContact CD1-CB 4.34Å; I624-V711 HydrophobicContact CD1-CG1 4Å; I624-V711 HydrophobicContact CD1-CG2 3.8Å; I624-V711 HydrophobicContact CG1-CG2 3.96Å
625D84.8Confident70.3Confident17 Ų1764 Ų649%0.09136%0.356CS..EExtended strand (participates in β ladder)trans-68.2151.1176.5-170.134.4000112.7D627 V638 V640 Y653 T707D625-D627 PolarHBondContact OD1-N 3.12Å; D625-V638 HydrophobicContact CB-CB 4.26Å; D625-V638 PolarHBondContact N-O 3.14Å; D625-V640 HydrophobicContact CB-CG2 3.91Å; D625-Y653 HydrophobicContact CB-CD1 4.46Å; D625-Y653 HydrophobicContact CB-CE1 3.92Å; D625-T707 VanDerWaalsContact OD1-O 3.08Å
626C77.3Confident69.3Low15 Ų1570.9 Ų70.910%0.10138%0.382CS..  trans-145.417.7-174.8-76.60000113.3P628 T707 R709C626-P628 WeakPolarHBondContact O-CD 3.22Å; C626-T707 WeakPolarHBondContact CA-O 3.4Å; C626-T707 HydrophobicContact CB-CG2 3.94Å; C626-T707 WeakPolarHBondContact CB-O 3.47Å; C626-T707 PolarHBondContact N-O 3.23Å; C626-R709 WeakPolarHBondContact SG-CD 3.31Å; C626-R709 WeakPolarHBondContact SG-CG 3.3Å
627D69.7Low68.8Low5 Ų568.5 Ų68.53%0.02738%0.376CS..  trans-74.9123.7167.2-160.8-58.7000110.6D625 S629 L630 S753D625-D627 PolarHBondContact OD1-N 3.12Å; D627-S629 PolarHBondContact O-N 2.93Å; D627-S629 PolarHBondContact OD1-N 3.48Å; D627-S629 PolarHBondContact OD1-OG 2.88Å; D627-L630 PolarHBondContact O-N 3.32Å; D627-S753 PolarHBondContact OD2-N 3.43Å; D627-S753 VanDerWaalsContact OD2-N 3.08Å
628P57.8Low68.6Low56 Ų5667.8 Ų67.836%0.36438%0.377SS..THydrogen-bonded Turntrans-60.7-14179.9-24.435.3000115.7C626 P681C626-P628 WeakPolarHBondContact O-CD 3.22Å; P628-P681 HydrophobicContact CG-CG 4.14Å
629S53.8Low68.7Low80 Ų8064.4 Ų64.456%0.55936%0.362SS*.THydrogen-bonded Turntrans-79.9-13.1-177.763.80000115.4D627D627-S629 PolarHBondContact O-N 2.93Å; D627-S629 PolarHBondContact OD1-N 3.48Å; D627-S629 PolarHBondContact OD1-OG 2.88Å
630L52.1Low69Low106 Ų10664 Ų6456%0.55536%0.358SS*.SBendtrans-106.5-1.1-179.8-68.9171.2000113.4D627 D632D627-L630 PolarHBondContact O-N 3.32Å; L630-D632 PolarHBondContact O-N 2.88Å
631I50.8Low69Low98 Ų9865 Ų6550%0.50336%0.358SS..  trans-88.894.1-177-53.1173.1000109.6
632D46.4Very low69.1Low132 Ų13262.4 Ų62.471%0.70635%0.349SS*.  trans-52.3154.3162-108.7-34.1000110.9L630 T634L630-D632 PolarHBondContact O-N 2.88Å; D632-T634 CarbonylContact O-C 3.55Å; D632-T634 PolarHBondContact O-N 3.17Å
633A49.9Very low69.3Low110 Ų11061.2 Ų61.291%0.90934%0.338SS*.SBendtrans-63.2-3.3-17300000115.1
634T52.6Low69.4Low84 Ų8461.2 Ų61.252%0.51534%0.337SS..SBendtrans-97.3118.7166.865.50000110.6D632 R636D632-T634 CarbonylContact O-C 3.55Å; D632-T634 PolarHBondContact O-N 3.17Å; T634-R636 PolarHBondContact O-N 3.23Å
635H54.2Low69.5Low195 Ų19561 Ų6190%0.90334%0.336SS*.  trans-55.199174.9-70.2-68.5000112.4
636R61.5Low69.7Low158 Ų15862.7 Ų62.760%0.59635%0.345SS*.  trans-125.8119.5173.9-72.1172168.9-111.12.6107.9T634 E657T634-R636 PolarHBondContact O-N 3.23Å; R636-E657 IonicContact CZ-OE1 3.36Å; R636-E657 VanDerWaalsContact CZ-OE1 3.24Å; R636-E657 IonicContact NH1-OE1 3.66Å; R636-E657 PolarHBondContact NH1-OE1 2.86Å; R636-E657 IonicContact NH2-OE1 2.8Å; R636-E657 PolarHBondContact NH2-OE1 2.8Å
637D71.2Confident70.2Confident103 Ų10363.2 Ų63.255%0.55135%0.349SS*.  trans-75.5123.5172.4-76-15.1000108.8I624 R709I624-D637 HydrophobicContact CD1-CB 3.95Å; I624-D637 HydrophobicContact CG1-CB 4.21Å; I624-D637 HydrophobicContact CG2-CB 3.82Å; D637-R709 IonicContact OD1-CZ 3.8Å; D637-R709 IonicContact OD1-NH2 3.81Å; D637-R709 PolarHBondContact OD1-NH2 3.23Å; D637-R709 IonicContact OD2-CZ 2.98Å; D637-R709 IonicContact OD2-NH2 3.28Å; D637-R709 PolarHBondContact OD2-NH2 3.36Å
638V76.4Confident71.2Confident53 Ų5363 Ų6332%0.32135%0.348SS..  trans-89.4114.1172.3-179.50000108.3I624 D625 Y653I624-V638 VanDerWaalsContact CA-O 3.31Å; I624-V638 WeakPolarHBondContact CA-O 3.39Å; D625-V638 HydrophobicContact CB-CB 4.26Å; D625-V638 PolarHBondContact N-O 3.14Å; V638-Y653 HydrophobicContact CG1-CD1 4.16Å
639D81.4Confident72.8Confident17 Ų1760.3 Ų60.39%0.09133%0.331CS..EExtended strand (participates in β ladder)trans-71.1128178.1-124.362.4000109.3Y654 F1072 R1076D639-Y654 WeakPolarHBondContact O-CB 3.42Å; D639-Y654 PolarHBondContact O-N 3.39Å; D639-F1072 WeakPolarHBondContact OD2-CD1 3.43Å; D639-R1076 IonicContact OD1-CZ 2.74Å; D639-R1076 IonicContact OD1-NH2 2.76Å; D639-R1076 PolarHBondContact OD1-NH2 2.91Å; D639-R1076 IonicContact OD2-CZ 2.71Å; D639-R1076 IonicContact OD2-NH2 3.65Å; D639-R1076 PolarHBondContact OD2-NH2 2.95Å
640V84.9Confident74.5Confident0 Ų056.7 Ų56.70%031%0.305CS..EExtended strand (participates in β ladder)trans-122.3131.1-178-179.80000109.6L623 D625 V651 A652 Y653 L708L623-V640 PolarHBondContact N-O 3.42Å; L623-V640 PolarHBondContact O-N 2.78Å; D625-V640 HydrophobicContact CB-CG2 3.91Å; V640-V651 HydrophobicContact CG1-CG1 3.69Å; V640-A652 WeakPolarHBondContact CA-O 3.42Å; V640-Y653 HydrophobicContact CG2-CD1 3.67Å; V640-Y653 HydrophobicContact CG2-CE1 3.84Å; V640-Y653 HydrophobicContact CG2-CG 4.22Å; V640-L708 HydrophobicContact CB-CD2 4.28Å; V640-L708 HydrophobicContact CG1-CD2 4Å; V640-L708 HydrophobicContact CG2-CD2 4.22Å
641L83.5Confident76.2Confident39 Ų3951.6 Ų51.620%0.20428%0.278CS..EExtended strand (participates in β ladder)trans-99.5114.6172.8-176.464.9000109.5L643 A652L641-L643 HydrophobicContact CD1-CD2 3.85Å; L641-L643 HydrophobicContact CD2-CD1 4.49Å; L641-L643 HydrophobicContact CD2-CD2 4.02Å; L641-L643 HydrophobicContact CD2-CG 4.38Å; L641-L643 HydrophobicContact CG-CD2 3.75Å; L641-L643 HydrophobicContact CG-CG 4.14Å; L641-A652 HydrophobicContact CB-CB 4.36Å; L641-A652 PolarHBondContact N-O 3.44Å; L641-A652 PolarHBondContact O-N 3.13Å
642L87.8Confident77.8Confident0 Ų047.4 Ų47.40%026%0.258CS..EExtended strand (participates in β ladder)trans-97.4123170.2176.267.3000108.7G620 W621 L623 Y649 Y650 V651 M692 L694 I726G620-L642 CarbonylContact C-O 3.56Å; G620-L642 VanDerWaalsContact CA-O 3.24Å; G620-L642 WeakPolarHBondContact CA-O 3.36Å; W621-L642 HydrophobicContact CE3-CB 4.47Å; W621-L642 HydrophobicContact CE3-CD2 3.98Å; W621-L642 HydrophobicContact CE3-CG 4.05Å; W621-L642 HydrophobicContact CZ3-CD2 4.38Å; W621-L642 HydrophobicContact CZ3-CG 4.45Å; W621-L642 PolarHBondContact N-O 2.92Å; W621-L642 PolarHBondContact O-N 3.43Å; L623-L642 HydrophobicContact CD1-CB 3.91Å; L623-L642 HydrophobicContact CD1-CD2 3.8Å; L642-Y649 HydrophobicContact CD1-CD2 3.85Å; L642-Y650 CarbonylContact C-O 2.9Å; L642-Y650 VanDerWaalsContact CA-O 3.3Å; L642-Y650 WeakPolarHBondContact CA-O 3.35Å; L642-V651 HydrophobicContact CD1-CG2 4.15Å; L642-M692 HydrophobicContact CD2-CE 4.2Å; L642-L694 HydrophobicContact CD1-CD1 4.25Å; L642-I726 HydrophobicContact CD2-CG2 3.66Å
643L86.1Confident79.5Confident11 Ų1141.8 Ų41.86%0.05823%0.227CC..EExtended strand (participates in β ladder)trans-116.8153171.2-45.4172.6000110.3L610 F617 L641 Y649 Y650L610-L643 HydrophobicContact CD1-CD1 4.05Å; L610-L643 HydrophobicContact CD2-CD1 3.82Å; L610-L643 HydrophobicContact CG-CD1 3.92Å; F617-L643 HydrophobicContact CE2-CD2 4.26Å; L641-L643 HydrophobicContact CD1-CD2 3.85Å; L641-L643 HydrophobicContact CD2-CD1 4.49Å; L641-L643 HydrophobicContact CD2-CD2 4.02Å; L641-L643 HydrophobicContact CD2-CG 4.38Å; L641-L643 HydrophobicContact CG-CD2 3.75Å; L641-L643 HydrophobicContact CG-CG 4.14Å; L643-Y649 CarbonylContact O-C 3.49Å; L643-Y649 VanDerWaalsContact O-CA 3.27Å; L643-Y649 WeakPolarHBondContact O-CA 3.3Å; L643-Y649 WeakPolarHBondContact O-CB 3.47Å; L643-Y650 HydrophobicContact CB-CD2 4.3Å; L643-Y650 PolarHBondContact N-O 2.82Å; L643-Y650 PolarHBondContact O-N 3.25Å
644L89.3Confident80.7Confident1 Ų138.3 Ų38.31%0.00519%0.191CC..EExtended strand (participates in β ladder)trans-131.8127.6178.9179.258000110.1H618 G619 W621 L669 M729 L730 T733H618-L644 HydrophobicContact CB-CD2 4.5Å; H618-L644 HydrophobicContact CB-CG 4.17Å; H618-L644 PolarHBondContact N-O 3.3Å; G619-L644 PolarHBondContact N-O 3.16Å; G619-L644 PolarHBondContact O-N 3.32Å; W621-L644 HydrophobicContact CH2-CB 4.16Å; W621-L644 HydrophobicContact CH2-CD2 4.02Å; W621-L644 HydrophobicContact CZ3-CB 3.85Å; W621-L644 HydrophobicContact CZ3-CD2 4.4Å; L644-L669 HydrophobicContact CD1-CD1 3.89Å; L644-L669 HydrophobicContact CD1-CD2 3.86Å; L644-L669 HydrophobicContact CD1-CG 4.32Å; L644-M729 HydrophobicContact CD2-CB 4.48Å; L644-M729 HydrophobicContact CD2-CG 3.97Å; L644-L730 HydrophobicContact CD1-CD2 3.7Å; L644-L730 HydrophobicContact CD2-CD2 4.09Å; L644-L730 HydrophobicContact CD2-CG 4.35Å; L644-L730 HydrophobicContact CG-CD2 4.41Å; L644-T733 HydrophobicContact CD1-CG2 4.32Å
645S88.8Confident81.6Confident0 Ų036.7 Ų36.70%018%0.179CC..EExtended strand (participates in β ladder)trans-106.9-174.9167.677.90000111.1E615 K616 S647 A648 T733E615-S645 WeakPolarHBondContact OE2-CB 3.45Å; E615-S645 PolarHBondContact OE2-OG 3.31Å; K616-S645 CarbonylContact O-C 3.59Å; K616-S645 WeakPolarHBondContact O-CA 3.35Å; K616-S645 WeakPolarHBondContact O-CB 3.35Å; S645-S647 PolarHBondContact O-N 2.83Å; S645-S647 PolarHBondContact OG-N 3.18Å; S645-A648 PolarHBondContact N-O 3.05Å; S645-A648 PolarHBondContact OG-N 3.02Å; S645-A648 PolarHBondContact OG-O 2.95Å; S645-A648 VanDerWaalsContact OG-O 3.11Å; S645-T733 WeakPolarHBondContact O-CG2 3.45Å
646N88Confident82Confident53 Ų5332.2 Ų32.228%0.28316%0.162SC..SBendtrans-70.2-7.9172.265-51.5000115.3E615 K616E615-N646 WeakPolarHBondContact CA-OD1 3.08Å; K616-N646 HydrophobicContact CB-CB 4.45Å; K616-N646 PolarHBondContact N-OD1 3.1Å; K616-N646 PolarHBondContact O-N 3.02Å
647S87.8Confident82Confident26 Ų2631.4 Ų31.418%0.18217%0.165CC..SBendtrans-141-19.7-176.662.10000115.1S645 L669S645-S647 PolarHBondContact O-N 2.83Å; S645-S647 PolarHBondContact OG-N 3.18Å; S647-L669 PolarHBondContact O-N 3.36Å
648A90.7Very high81.5Confident0 Ų030.1 Ų30.10%016%0.16CC..EExtended strand (participates in β ladder)trans-138.7160.5-176.800000111.8S645 Y650 R666 L667S645-A648 PolarHBondContact N-O 3.05Å; S645-A648 PolarHBondContact OG-N 3.02Å; S645-A648 PolarHBondContact OG-O 2.95Å; S645-A648 VanDerWaalsContact OG-O 3.11Å; A648-Y650 HydrophobicContact CB-CE2 4.07Å; A648-R666 HydrophobicContact CB-CG 3.94Å; A648-L667 CarbonylContact C-O 3.55Å; A648-L667 VanDerWaalsContact CA-O 3.24Å; A648-L667 WeakPolarHBondContact CA-O 3.12Å; A648-L667 VanDerWaalsContact CB-O 3.32Å; A648-L667 WeakPolarHBondContact CB-O 3.24Å
649Y92.2Very high80.8Confident0 Ų031.4 Ų31.40%017%0.166CC..EExtended strand (participates in β ladder)trans-119.7154.7162.273.8-80.8000110.2L642 L643 V651 L667 L669 L672 L694 Y696 L730L642-Y649 HydrophobicContact CD1-CD2 3.85Å; L643-Y649 CarbonylContact O-C 3.49Å; L643-Y649 VanDerWaalsContact O-CA 3.27Å; L643-Y649 WeakPolarHBondContact O-CA 3.3Å; L643-Y649 WeakPolarHBondContact O-CB 3.47Å; Y649-V651 HydrophobicContact CD2-CG2 3.92Å; Y649-V651 HydrophobicContact CE2-CG2 3.8Å; Y649-L667 HydrophobicContact CD1-CB 3.97Å; Y649-L667 HydrophobicContact CE1-CB 3.51Å; Y649-L667 HydrophobicContact CE1-CD1 4.37Å; Y649-L667 HydrophobicContact CE2-CB 4.13Å; Y649-L667 HydrophobicContact CE2-CD1 3.77Å; Y649-L667 HydrophobicContact CG-CB 4.46Å; Y649-L667 PolarHBondContact N-O 2.98Å; Y649-L667 PolarHBondContact O-N 3.41Å; Y649-L667 WeakPolarHBondContact OH-CD1 3.43Å; Y649-L669 HydrophobicContact CD1-CD2 3.97Å; Y649-L672 HydrophobicContact CE1-CB 4.07Å; Y649-L672 HydrophobicContact CE1-CD1 3.95Å; Y649-L672 HydrophobicContact CE1-CG 4.4Å; Y649-L694 HydrophobicContact CD2-CD1 4.39Å; Y649-L694 HydrophobicContact CE2-CD1 4.01Å; Y649-Y696 WeakPolarHBondContact OH-CB 3.46Å; Y649-L730 HydrophobicContact CG-CD2 4.48Å
650Y88.6Confident80.2Confident4 Ų436.8 Ų36.82%0.01619%0.188CC..EExtended strand (participates in β ladder)trans-126.3132.1-173-60.9-105.1000109.5L611 P612 E615 L642 L643 A648 Y664 Q665 R666L611-Y650 HydrophobicContact CD2-CD2 4.1Å; L611-Y650 HydrophobicContact CD2-CE1 4.42Å; L611-Y650 HydrophobicContact CD2-CE2 3.37Å; P612-Y650 WeakPolarHBondContact CD-OH 3.41Å; E615-Y650 VanDerWaalsContact CD-OH 3.25Å; E615-Y650 PolarHBondContact OE1-OH 3.49Å; E615-Y650 VanDerWaalsContact OE1-OH 3.12Å; E615-Y650 PolarHBondContact OE2-OH 3.09Å; L642-Y650 CarbonylContact C-O 2.9Å; L642-Y650 VanDerWaalsContact CA-O 3.3Å; L642-Y650 WeakPolarHBondContact CA-O 3.35Å; L643-Y650 HydrophobicContact CB-CD2 4.3Å; L643-Y650 PolarHBondContact N-O 2.82Å; L643-Y650 PolarHBondContact O-N 3.25Å; A648-Y650 HydrophobicContact CB-CE2 4.07Å; Y650-Y664 HydrophobicContact CD1-CE2 4.04Å; Y650-Y664 AromaticContact CD1-CZ 3.77Å; Y650-Y664 VanDerWaalsContact CD1-OH 3.22Å; Y650-Y664 WeakPolarHBondContact CD1-OH 3.42Å; Y650-Y664 VanDerWaalsContact CE1-OH 3.27Å; Y650-Y664 WeakPolarHBondContact CE1-OH 3.43Å; Y650-Q665 CarbonylContact C-O 3.58Å; Y650-Q665 VanDerWaalsContact CA-O 3.25Å; Y650-Q665 WeakPolarHBondContact CA-O 3.42Å; Y650-R666 HydrophobicContact CD1-CB 3.74Å; Y650-R666 HydrophobicContact CD1-CG 3.98Å; Y650-R666 HydrophobicContact CE1-CB 3.61Å; Y650-R666 HydrophobicContact CE1-CG 3.48Å; Y650-R666 VanDerWaalsContact CE1-CG 3.48Å; Y650-R666 HydrophobicContact CE2-CG 4.38Å; Y650-R666 PolarHBondContact OH-NE 3.35Å
651V88.3Confident79.4Confident0 Ų040.5 Ų40.50%021%0.211CC..EExtended strand (participates in β ladder)trans-119.9119175.7-170.90000108.1V640 L642 Y649 Y653 Q665V640-V651 HydrophobicContact CG1-CG1 3.69Å; L642-V651 HydrophobicContact CD1-CG2 4.15Å; Y649-V651 HydrophobicContact CD2-CG2 3.92Å; Y649-V651 HydrophobicContact CE2-CG2 3.8Å; V651-Y653 HydrophobicContact CG1-CD2 4.09Å; V651-Y653 HydrophobicContact CG1-CE2 3.56Å; V651-Q665 PolarHBondContact N-O 3Å; V651-Q665 PolarHBondContact O-N 3.5Å
652A83.3Confident78.6Confident10 Ų1044.6 Ų44.68%0.08323%0.232CC..EExtended strand (participates in β ladder)trans-124.2116.6178.300000110.4V640 L641 V661 Q663 Y664V640-A652 WeakPolarHBondContact CA-O 3.42Å; L641-A652 HydrophobicContact CB-CB 4.36Å; L641-A652 PolarHBondContact N-O 3.44Å; L641-A652 PolarHBondContact O-N 3.13Å; A652-V661 HydrophobicContact CB-CG1 4.08Å; A652-Q663 CarbonylContact C-O 3.56Å; A652-Q663 WeakPolarHBondContact CA-O 3.42Å; A652-Y664 HydrophobicContact CB-CD2 4.08Å
653Y82.5Confident77.9Confident13 Ų1346.5 Ų46.55%0.05124%0.241CC..EExtended strand (participates in β ladder)trans-88.3131.6177.7-70.4-104.8000109.5D625 V638 V640 V651 V661 N662 Q663 H706D625-Y653 HydrophobicContact CB-CD1 4.46Å; D625-Y653 HydrophobicContact CB-CE1 3.92Å; V638-Y653 HydrophobicContact CG1-CD1 4.16Å; V640-Y653 HydrophobicContact CG2-CD1 3.67Å; V640-Y653 HydrophobicContact CG2-CE1 3.84Å; V640-Y653 HydrophobicContact CG2-CG 4.22Å; V651-Y653 HydrophobicContact CG1-CD2 4.09Å; V651-Y653 HydrophobicContact CG1-CE2 3.56Å; Y653-V661 CarbonylContact O-C 3.45Å; Y653-V661 WeakPolarHBondContact O-CA 3.39Å; Y653-N662 PolarHBondContact O-N 3.41Å; Y653-Q663 HydrophobicContact CD2-CB 4.14Å; Y653-Q663 HydrophobicContact CG-CB 4.44Å; Y653-Q663 PolarHBondContact N-O 2.88Å; Y653-Q663 PolarHBondContact O-N 3.31Å; Y653-H706 AromaticContact CE2-ND1 3.89Å; Y653-H706 AromaticContact CZ-ND1 3.86Å; Y653-H706 PolarHBondContact OH-ND1 3.23Å
654Y74.8Confident77.7Confident37 Ų3750 Ų5015%0.14526%0.255CS..EExtended strand (participates in β ladder)trans-111.2140.2-174.4-153.9-105.3000112.9D639 D659 K660 V661 F1072D639-Y654 WeakPolarHBondContact O-CB 3.42Å; D639-Y654 PolarHBondContact O-N 3.39Å; Y654-D659 VanDerWaalsContact CZ-C 3.43Å; Y654-D659 PolarHBondContact OH-O 2.99Å; Y654-D659 PolarHBondContact OH-OD1 2.87Å; Y654-D659 VanDerWaalsContact OH-OD1 3.1Å; Y654-K660 VanDerWaalsContact CD2-C 3.43Å; Y654-K660 WeakPolarHBondContact CD2-O 3.43Å; Y654-V661 HydrophobicContact CD2-CG2 3.9Å; Y654-V661 HydrophobicContact CE2-CG2 4.14Å; Y654-F1072 AromaticContact CD1-CD2 3.84Å; Y654-F1072 HydrophobicContact CD1-CD2 3.84Å; Y654-F1072 AromaticContact CD1-CE2 3.55Å; Y654-F1072 HydrophobicContact CD1-CE2 3.55Å; Y654-F1072 HydrophobicContact CD1-CZ 4.05Å; Y654-F1072 AromaticContact CD2-CE2 3.67Å; Y654-F1072 HydrophobicContact CD2-CE2 3.67Å; Y654-F1072 AromaticContact CD2-CZ 3.83Å; Y654-F1072 HydrophobicContact CD2-CZ 3.83Å; Y654-F1072 AromaticContact CE1-CD2 3.59Å; Y654-F1072 HydrophobicContact CE1-CD2 3.59Å; Y654-F1072 AromaticContact CE1-CE2 3.44Å; Y654-F1072 HydrophobicContact CE1-CE2 3.44Å; Y654-F1072 VanDerWaalsContact CE1-CE2 3.44Å; Y654-F1072 HydrophobicContact CE1-CZ 4.36Å; Y654-F1072 AromaticContact CE2-CE2 3.59Å; Y654-F1072 HydrophobicContact CE2-CE2 3.59Å; Y654-F1072 HydrophobicContact CE2-CZ 4.19Å; Y654-F1072 HydrophobicContact CG-CD2 4.38Å; Y654-F1072 AromaticContact CG-CE2 3.65Å; Y654-F1072 HydrophobicContact CG-CE2 3.65Å; Y654-F1072 AromaticContact CG-CZ 3.76Å; Y654-F1072 HydrophobicContact CG-CZ 3.76Å; Y654-F1072 AromaticContact CZ-CD2 3.96Å; Y654-F1072 AromaticContact CZ-CE2 3.45Å; Y654-F1072 VanDerWaalsContact CZ-CE2 3.45Å
655D72.3Confident77.5Confident51 Ų5150 Ų5027%0.27326%0.255SS..EExtended strand (participates in β ladder)trans-101.5112.7172.4-173.7-37000109.7E657 V658 D659 K660 N662D655-E657 VanDerWaalsContact C-N 3.34Å; D655-E657 WeakPolarHBondContact OD1-CA 3.29Å; D655-E657 PolarHBondContact OD1-N 3.41Å; D655-V658 HydrophobicContact CB-CB 4.22Å; D655-V658 PolarHBondContact OD1-N 3.11Å; D655-V658 WeakPolarHBondContact OD2-CG2 3.33Å; D655-D659 WeakPolarHBondContact O-CA 3.39Å; D655-D659 PolarHBondContact O-N 3.26Å; D655-K660 PolarHBondContact N-O 3.03Å; D655-K660 PolarHBondContact O-N 3.22Å; D655-N662 HydrophobicContact CB-CB 4.4Å
656D63.3Low77.5Confident100 Ų10053.5 Ų53.554%0.53527%0.268SS..THydrogen-bonded Turntrans-78-13.5-175.5-135.420.9000113S1070D656-S1070 VanDerWaalsContact OD1-CB 3.25Å; D656-S1070 WeakPolarHBondContact OD1-CB 3.32Å; D656-S1070 PolarHBondContact OD1-OG 3.01Å
657E60Low77.6Confident142 Ų14251.2 Ų51.266%0.66426%0.255SS*.THydrogen-bonded Turntrans-90.8-32.4171.8-69.9-164.8-16600112.1R636 D655R636-E657 IonicContact CZ-OE1 3.36Å; R636-E657 VanDerWaalsContact CZ-OE1 3.24Å; R636-E657 IonicContact NH1-OE1 3.66Å; R636-E657 PolarHBondContact NH1-OE1 2.86Å; R636-E657 IonicContact NH2-OE1 2.8Å; R636-E657 PolarHBondContact NH2-OE1 2.8Å; D655-E657 VanDerWaalsContact C-N 3.34Å; D655-E657 WeakPolarHBondContact OD1-CA 3.29Å; D655-E657 PolarHBondContact OD1-N 3.41Å
658V62.4Low77.7Confident75 Ų7551 Ų5146%0.45525%0.254SS..THydrogen-bonded Turntrans-95.9-12.5-177.8-171.70000113.1D655 K660D655-V658 HydrophobicContact CB-CB 4.22Å; D655-V658 PolarHBondContact OD1-N 3.11Å; D655-V658 WeakPolarHBondContact OD2-CG2 3.33Å; V658-K660 VanDerWaalsContact C-N 3.34Å; V658-K660 HydrophobicContact CG1-CB 4.33Å; V658-K660 HydrophobicContact CG1-CD 3.77Å; V658-K660 HydrophobicContact CG1-CG 4.15Å
659D60.2Low77.7Confident81 Ų8151 Ų5143%0.43325%0.254SS..THydrogen-bonded Turntrans59.340.9-178.1-156.339.3000112Y654 D655 P1071Y654-D659 VanDerWaalsContact CZ-C 3.43Å; Y654-D659 PolarHBondContact OH-O 2.99Å; Y654-D659 PolarHBondContact OH-OD1 2.87Å; Y654-D659 VanDerWaalsContact OH-OD1 3.1Å; D655-D659 WeakPolarHBondContact O-CA 3.39Å; D655-D659 PolarHBondContact O-N 3.26Å; D659-P1071 VanDerWaalsContact OD1-CD 3.3Å; D659-P1071 WeakPolarHBondContact OD1-CD 3.25Å; D659-P1071 VanDerWaalsContact OD1-CG 3.31Å; D659-P1071 WeakPolarHBondContact OD1-CG 3.24Å
660K69Low77.6Confident130 Ų13057.4 Ų57.457%0.56528%0.284SS*.EExtended strand (participates in β ladder)trans-142.2154.2-174.5-68.8178.7-156.2158.20113.1Y654 D655 V658 N662Y654-K660 VanDerWaalsContact CD2-C 3.43Å; Y654-K660 WeakPolarHBondContact CD2-O 3.43Å; D655-K660 PolarHBondContact N-O 3.03Å; D655-K660 PolarHBondContact O-N 3.22Å; V658-K660 VanDerWaalsContact C-N 3.34Å; V658-K660 HydrophobicContact CG1-CB 4.33Å; V658-K660 HydrophobicContact CG1-CD 3.77Å; V658-K660 HydrophobicContact CG1-CG 4.15Å; K660-N662 PolarHBondContact O-N 3.43Å
661V68.4Low77.6Confident78 Ų7860.1 Ų60.147%0.47330%0.299SS..EExtended strand (participates in β ladder)trans-68.9122.9163.7179.70000108.2A652 Y653 Y654 Q663A652-V661 HydrophobicContact CB-CG1 4.08Å; Y653-V661 CarbonylContact O-C 3.45Å; Y653-V661 WeakPolarHBondContact O-CA 3.39Å; Y654-V661 HydrophobicContact CD2-CG2 3.9Å; Y654-V661 HydrophobicContact CE2-CG2 4.14Å; V661-Q663 WeakPolarHBondContact CG1-O 3.46Å
662N66.5Low77.8Confident124 Ų12460.1 Ų60.166%0.66330%0.299SS*.EExtended strand (participates in β ladder)trans-89.9-38179.8-164.910.7000111.3Y653 D655 K660Y653-N662 PolarHBondContact O-N 3.41Å; D655-N662 HydrophobicContact CB-CB 4.4Å; K660-N662 PolarHBondContact O-N 3.43Å
663Q74.3Confident78.2Confident40 Ų4062.2 Ų62.219%0.18731%0.307CS..EExtended strand (participates in β ladder)trans-137.3143.3175.4-161.9175.213.900111.3A652 Y653 V661 H756 D758A652-Q663 CarbonylContact C-O 3.56Å; A652-Q663 WeakPolarHBondContact CA-O 3.42Å; Y653-Q663 HydrophobicContact CD2-CB 4.14Å; Y653-Q663 HydrophobicContact CG-CB 4.44Å; Y653-Q663 PolarHBondContact N-O 2.88Å; Y653-Q663 PolarHBondContact O-N 3.31Å; V661-Q663 WeakPolarHBondContact CG1-O 3.46Å; Q663-H756 PolarHBondContact NE2-O 3.31Å; Q663-D758 WeakPolarHBondContact CG-OD1 3.36Å
664Y81.6Confident78.7Confident85 Ų8564.2 Ų64.233%0.33332%0.316SS..EExtended strand (participates in β ladder)trans-141.5126.1-179.8174.4-96.3000112.5Y650 A652 D758Y650-Y664 HydrophobicContact CD1-CE2 4.04Å; Y650-Y664 AromaticContact CD1-CZ 3.77Å; Y650-Y664 VanDerWaalsContact CD1-OH 3.22Å; Y650-Y664 WeakPolarHBondContact CD1-OH 3.42Å; Y650-Y664 VanDerWaalsContact CE1-OH 3.27Å; Y650-Y664 WeakPolarHBondContact CE1-OH 3.43Å; A652-Y664 HydrophobicContact CB-CD2 4.08Å; Y664-D758 PolarHBondContact N-OD1 2.79Å
665Q84.9Confident79.7Confident2 Ų262.5 Ų62.51%0.00931%0.309CS..EExtended strand (participates in β ladder)trans-129.7136.1175.4-66.9-179.7-37.100111.3Y650 V651 Y696 H706 E757 I759Y650-Q665 CarbonylContact C-O 3.58Å; Y650-Q665 VanDerWaalsContact CA-O 3.25Å; Y650-Q665 WeakPolarHBondContact CA-O 3.42Å; V651-Q665 PolarHBondContact N-O 3Å; V651-Q665 PolarHBondContact O-N 3.5Å; Q665-Y696 PolarHBondContact NE2-OH 3.41Å; Q665-H706 PolarHBondContact OE1-CE1 2.86Å; Q665-H706 PolarHBondContact OE1-NE2 2.9Å; Q665-H706 VanDerWaalsContact OE1-NE2 3.17Å; Q665-E757 PolarHBondContact NE2-O 2.77Å; Q665-I759 HydrophobicContact CG-CD1 4.38Å; Q665-I759 HydrophobicContact CG-CG1 4.16Å
666R88.6Confident80.8Confident73 Ų7360.1 Ų60.128%0.27530%0.296SS..EExtended strand (participates in β ladder)trans-103.4126.2159.7177.3-175.7174.7-81.65.6107.5E615 A648 Y650 I760E615-R666 IonicContact OE1-CZ 2.63Å; E615-R666 IonicContact OE1-NE 3.54Å; E615-R666 PolarHBondContact OE1-NE 2.82Å; E615-R666 IonicContact OE1-NH2 3.8Å; E615-R666 PolarHBondContact OE1-NH2 2.95Å; A648-R666 HydrophobicContact CB-CG 3.94Å; Y650-R666 HydrophobicContact CD1-CB 3.74Å; Y650-R666 HydrophobicContact CD1-CG 3.98Å; Y650-R666 HydrophobicContact CE1-CB 3.61Å; Y650-R666 HydrophobicContact CE1-CG 3.48Å; Y650-R666 VanDerWaalsContact CE1-CG 3.48Å; Y650-R666 HydrophobicContact CE2-CG 4.38Å; Y650-R666 PolarHBondContact OH-NE 3.35Å; R666-I760 HydrophobicContact CB-CD1 4.39Å
667L89.5Confident82.2Confident4 Ų455.5 Ų55.52%0.02127%0.271CS..EExtended strand (participates in β ladder)trans-122.7134.1-178.1-76.5164.4000109.6A648 Y649 Y696 I759A648-L667 CarbonylContact C-O 3.55Å; A648-L667 VanDerWaalsContact CA-O 3.24Å; A648-L667 WeakPolarHBondContact CA-O 3.12Å; A648-L667 VanDerWaalsContact CB-O 3.32Å; A648-L667 WeakPolarHBondContact CB-O 3.24Å; Y649-L667 HydrophobicContact CD1-CB 3.97Å; Y649-L667 HydrophobicContact CE1-CB 3.51Å; Y649-L667 HydrophobicContact CE1-CD1 4.37Å; Y649-L667 HydrophobicContact CE2-CB 4.13Å; Y649-L667 HydrophobicContact CE2-CD1 3.77Å; Y649-L667 HydrophobicContact CG-CB 4.46Å; Y649-L667 PolarHBondContact N-O 2.98Å; Y649-L667 PolarHBondContact O-N 3.41Å; Y649-L667 WeakPolarHBondContact OH-CD1 3.43Å; L667-Y696 HydrophobicContact CD1-CD1 4.13Å; L667-Y696 HydrophobicContact CD1-CD2 3.95Å; L667-Y696 HydrophobicContact CD1-CE1 4.16Å; L667-Y696 HydrophobicContact CD1-CE2 3.98Å; L667-Y696 HydrophobicContact CD1-CG 4.02Å; L667-Y696 HydrophobicContact CD2-CD2 3.4Å; L667-Y696 VanDerWaalsContact CD2-CD2 3.4Å; L667-Y696 HydrophobicContact CD2-CE2 3.54Å; L667-Y696 HydrophobicContact CD2-CG 4.18Å; L667-Y696 HydrophobicContact CG-CD2 4.34Å; L667-Y696 HydrophobicContact CG-CE2 4.44Å; L667-I759 HydrophobicContact CD2-CD1 3.32Å; L667-I759 HydrophobicContact CG-CD1 4.07Å
668S89.8Confident83.6Confident22 Ų2249 Ų4915%0.15424%0.243CC..EExtended strand (participates in β ladder)trans-63.9140.6174.8-173.40000109.2E670 D671S668-E670 PolarHBondContact O-N 3.4Å; S668-E670 WeakPolarHBondContact OG-CB 3.41Å; S668-E670 PolarHBondContact OG-N 3.13Å; S668-E670 PolarHBondContact OG-OE2 2.89Å; S668-D671 WeakPolarHBondContact CB-OD2 3.37Å; S668-D671 PolarHBondContact O-N 2.87Å
669L90.9Very high84.8Confident0 Ų048 Ų480%024%0.238CC..THydrogen-bonded Turntrans-64.3-20.7169.8-75.8170000111.6L644 S647 Y649 L672 L730 T733 K734 M737L644-L669 HydrophobicContact CD1-CD1 3.89Å; L644-L669 HydrophobicContact CD1-CD2 3.86Å; L644-L669 HydrophobicContact CD1-CG 4.32Å; S647-L669 PolarHBondContact O-N 3.36Å; Y649-L669 HydrophobicContact CD1-CD2 3.97Å; L669-L672 HydrophobicContact CD2-CD2 4.38Å; L669-L672 PolarHBondContact O-N 2.78Å; L669-L730 HydrophobicContact CD2-CD2 3.97Å; L669-T733 HydrophobicContact CD1-CG2 3.61Å; L669-K734 HydrophobicContact CB-CG 4.33Å; L669-K734 VanDerWaalsContact O-CD 3.31Å; L669-K734 WeakPolarHBondContact O-CD 3.34Å; L669-K734 VanDerWaalsContact O-CE 3.25Å; L669-K734 WeakPolarHBondContact O-CE 3.43Å; L669-K734 PolarHBondContact O-NZ 2.84Å; L669-M737 HydrophobicContact CB-CE 4.37Å; L669-M737 HydrophobicContact CB-SD 3.62Å; L669-M737 HydrophobicContact CD1-SD 3.74Å; L669-M737 HydrophobicContact CG-SD 4.32Å
670E89.5Confident85.8Confident135 Ų13545.8 Ų45.863%0.63123%0.225SC*.THydrogen-bonded Turntrans-62.8-44.1172.4-61170.9146.800111.6S668 L672 K734 M737S668-E670 PolarHBondContact O-N 3.4Å; S668-E670 WeakPolarHBondContact OG-CB 3.41Å; S668-E670 PolarHBondContact OG-N 3.13Å; S668-E670 PolarHBondContact OG-OE2 2.89Å; E670-L672 VanDerWaalsContact C-N 3.27Å; E670-L672 PolarHBondContact O-N 3.32Å; E670-K734 PolarHBondContact O-NZ 3.3Å; E670-M737 HydrophobicContact CG-CE 4.12Å
671D90.4Very high85.9Confident60 Ų6040.1 Ų40.132%0.32120%0.201SC..THydrogen-bonded Turntrans-70.6-15.4-179-71.9-54.5000114.2S668 E673 Y696 R697S668-D671 WeakPolarHBondContact CB-OD2 3.37Å; S668-D671 PolarHBondContact O-N 2.87Å; D671-E673 WeakPolarHBondContact O-CG 3.41Å; D671-E673 PolarHBondContact O-N 3.49Å; D671-E673 VanDerWaalsContact O-N 3.09Å; D671-Y696 CarbonylContact O-C 3.6Å; D671-Y696 VanDerWaalsContact O-CA 3.31Å; D671-Y696 WeakPolarHBondContact O-CA 3.49Å; D671-R697 HydrophobicContact CB-CB 4.34Å; D671-R697 PolarHBondContact O-N 3.19Å
672L92.6Very high86Confident0 Ų038.2 Ų38.20%019%0.19CC..EExtended strand (participates in β ladder)trans-70.1101.3177.8-174.768.9000110.5Y649 L669 E670 I675 L694 L730 K734 V741Y649-L672 HydrophobicContact CE1-CB 4.07Å; Y649-L672 HydrophobicContact CE1-CD1 3.95Å; Y649-L672 HydrophobicContact CE1-CG 4.4Å; L669-L672 HydrophobicContact CD2-CD2 4.38Å; L669-L672 PolarHBondContact O-N 2.78Å; E670-L672 VanDerWaalsContact C-N 3.27Å; E670-L672 PolarHBondContact O-N 3.32Å; L672-I675 HydrophobicContact CD2-CD1 4.35Å; L672-I675 HydrophobicContact CD2-CG1 4.44Å; L672-L694 HydrophobicContact CD1-CB 4.03Å; L672-L694 HydrophobicContact CD1-CD2 4.33Å; L672-L730 HydrophobicContact CD2-CB 4.46Å; L672-L730 HydrophobicContact CD2-CD2 4.47Å; L672-K734 PolarHBondContact O-NZ 3.21Å; L672-V741 HydrophobicContact CD2-CG1 4.37Å; L672-V741 HydrophobicContact CD2-CG2 4.18Å; L672-V741 HydrophobicContact CG-CG2 4.07Å
673E91.5Very high85.9Confident54 Ų5438.1 Ų38.125%0.25219%0.189SC..EExtended strand (participates in β ladder)trans-77.8-38.9-169.9-57.6-163.912900113.1D671 H695 R697 S702D671-E673 WeakPolarHBondContact O-CG 3.41Å; D671-E673 PolarHBondContact O-N 3.49Å; D671-E673 VanDerWaalsContact O-N 3.09Å; E673-H695 PolarHBondContact N-O 2.88Å; E673-R697 HydrophobicContact CG-CB 4.21Å; E673-R697 IonicContact OE1-CZ 3.2Å; E673-R697 VanDerWaalsContact OE1-CZ 3.23Å; E673-R697 IonicContact OE1-NE 3.01Å; E673-R697 PolarHBondContact OE1-NE 3.42Å; E673-R697 IonicContact OE1-NH2 2.72Å; E673-R697 PolarHBondContact OE1-NH2 2.89Å; E673-S702 WeakPolarHBondContact OE2-CB 3.45Å
674K93.1Very high85.1Confident56 Ų5645.5 Ų45.524%0.24322%0.221CC..EExtended strand (participates in β ladder)trans-169.1158.8-178.756.1176.8174164.60111.4E676 H695 P742 I744K674-E676 HydrophobicContact CD-CG 4.27Å; K674-E676 WeakPolarHBondContact CE-OE1 3.42Å; K674-E676 IonicContact NZ-OE1 2.73Å; K674-E676 PolarHBondContact NZ-OE1 3.19Å; K674-H695 VanDerWaalsContact CE-CG 3.45Å; K674-H695 WeakPolarHBondContact CE-ND1 3.47Å; K674-H695 HydrophobicContact CG-CB 3.67Å; K674-H695 PolarHBondContact O-N 3.47Å; K674-P742 HydrophobicContact CB-CG 3.89Å; K674-I744 HydrophobicContact CD-CD1 4.28Å
675I95.5Very high84.3Confident0 Ų044.9 Ų44.90%024%0.24CC..EExtended strand (participates in β ladder)trans-115127.7170.8-53.5-178.7000108.5L672 I677 M692 R693 L694 A727 L730 V741 P742 I743 I744L672-I675 HydrophobicContact CD2-CD1 4.35Å; L672-I675 HydrophobicContact CD2-CG1 4.44Å; I675-I677 HydrophobicContact CG2-CG1 4.29Å; I675-M692 HydrophobicContact CG2-CG 3.58Å; I675-M692 HydrophobicContact CG2-SD 4.07Å; I675-R693 WeakPolarHBondContact CA-O 3.48Å; I675-L694 HydrophobicContact CB-CD2 4.44Å; I675-L694 HydrophobicContact CD1-CD2 3.89Å; I675-L694 HydrophobicContact CG1-CD2 3.78Å; I675-L694 HydrophobicContact CG2-CD2 4.03Å; I675-A727 HydrophobicContact CD1-CB 3.87Å; I675-A727 HydrophobicContact CG2-CB 3.84Å; I675-L730 HydrophobicContact CD1-CB 3.9Å; I675-L730 HydrophobicContact CD1-CD1 3.93Å; I675-V741 HydrophobicContact CG1-CG2 4.11Å; I675-P742 PolarHBondContact N-O 3.35Å; I675-I743 HydrophobicContact CB-CG1 4.49Å; I675-I743 CarbonylContact O-C 3.59Å; I675-I743 WeakPolarHBondContact O-CA 3.25Å; I675-I744 PolarHBondContact O-N 2.67Å
676E94.3Very high83.8Confident2 Ų253.8 Ų53.81%0.00928%0.279CS..EExtended strand (participates in β ladder)trans-114.2126.8175.5-58.3-180158.700109.7K674 M692 R693 H695 I744 K746 L748K674-E676 HydrophobicContact CD-CG 4.27Å; K674-E676 WeakPolarHBondContact CE-OE1 3.42Å; K674-E676 IonicContact NZ-OE1 2.73Å; K674-E676 PolarHBondContact NZ-OE1 3.19Å; E676-M692 CarbonylContact O-C 3.58Å; E676-R693 HydrophobicContact CB-CB 4.33Å; E676-R693 PolarHBondContact N-O 2.99Å; E676-R693 PolarHBondContact O-N 3.37Å; E676-H695 IonicContact OE1-NE2 2.86Å; E676-H695 IonicContact OE2-CD2 2.7Å; E676-H695 IonicContact OE2-CE1 3.7Å; E676-H695 IonicContact OE2-NE2 3.54Å; E676-H695 PolarHBondContact OE2-NE2 3.36Å; E676-I744 CarbonylContact C-O 3.59Å; E676-I744 WeakPolarHBondContact CA-O 3.43Å; E676-I744 HydrophobicContact CG-CB 4.42Å; E676-K746 VanDerWaalsContact OE1-CE 3.22Å; E676-K746 WeakPolarHBondContact OE1-CE 3.38Å; E676-K746 IonicContact OE1-NZ 2.61Å; E676-K746 PolarHBondContact OE1-NZ 3.26Å; E676-K746 WeakPolarHBondContact OE2-CE 3.47Å; E676-K746 IonicContact OE2-NZ 2.73Å; E676-K746 PolarHBondContact OE2-NZ 3.44Å; E676-L748 HydrophobicContact CB-CD2 3.86Å
677I93.4Very high83.1Confident2 Ų253.4 Ų53.41%0.0129%0.286CS..EExtended strand (participates in β ladder)trans-117.4135.1179.2-66.5174.4000109.7I675 C691 M692 K720 A727 I743 I744 E745 K746I675-I677 HydrophobicContact CG2-CG1 4.29Å; I677-C691 WeakPolarHBondContact CA-O 3.49Å; I677-M692 HydrophobicContact CG1-CB 4.23Å; I677-M692 HydrophobicContact CG1-CG 4.11Å; I677-K720 HydrophobicContact CG2-CG 4.19Å; I677-A727 HydrophobicContact CD1-CB 3.84Å; I677-I743 HydrophobicContact CD1-CG2 4.09Å; I677-I744 PolarHBondContact N-O 2.97Å; I677-E745 WeakPolarHBondContact O-CA 3.31Å; I677-K746 PolarHBondContact O-N 3.35Å; I677-K746 VanDerWaalsContact O-O 3.07Å
678G89.8Confident82.4Confident7 Ų760.8 Ų60.87%0.07232%0.318CS..EExtended strand (participates in β ladder)trans170.9-174.6171.700000114.3C691 K746G678-C691 PolarHBondContact N-O 2.91Å; G678-C691 PolarHBondContact O-N 3.19Å; G678-K746 WeakPolarHBondContact CA-O 3.29Å
679P86.6Confident82.1Confident54 Ų5462.1 Ų62.135%0.35132%0.321SS..EExtended strand (participates in β ladder)trans-61.2145.4-173.6-24.334.2000113.6P687P679-P687 HydrophobicContact CB-CB 3.81Å; P679-P687 HydrophobicContact CB-CG 3.76Å
680E81.3Confident82Confident33 Ų3362.3 Ų62.315%0.15432%0.323CS..  trans-51.5139.5-177.856.7172.7-172.500113.8T682 P687 K688 F689E680-T682 VanDerWaalsContact CD-CG2 3.48Å; E680-T682 HydrophobicContact CG-CG2 3.78Å; E680-T682 PolarHBondContact O-N 3.2Å; E680-T682 VanDerWaalsContact OE1-CG2 3.29Å; E680-T682 WeakPolarHBondContact OE1-CG2 3.25Å; E680-P687 HydrophobicContact CG-CB 3.47Å; E680-P687 VanDerWaalsContact CG-CB 3.47Å; E680-P687 WeakPolarHBondContact OE1-CA 3.29Å; E680-K688 PolarHBondContact OE1-N 3.41Å; E680-F689 PolarHBondContact N-O 3.34Å
681P71.9Confident82.1Confident11 Ų1155.9 Ų55.97%0.07129%0.293CS..  trans-78.944.5-175.134.6-37.7000113.3P628 R750P628-P681 HydrophobicContact CG-CG 4.14Å; P681-R750 HydrophobicContact CB-CG 4.3Å
682T69.8Low82.3Confident39 Ų3953 Ų5324%0.23928%0.277CS..  trans-52.9144.7-177.839.40000113.3E680 R750E680-T682 VanDerWaalsContact CD-CG2 3.48Å; E680-T682 HydrophobicContact CG-CG2 3.78Å; E680-T682 PolarHBondContact O-N 3.2Å; E680-T682 VanDerWaalsContact OE1-CG2 3.29Å; E680-T682 WeakPolarHBondContact OE1-CG2 3.25Å; T682-R750 PolarHBondContact O-NE 3.43Å; T682-R750 PolarHBondContact O-NH2 3.16Å
683L63.8Low82.3Confident122 Ų12253.1 Ų53.164%0.63928%0.278SS*.SBendtrans-72.5-50.3176.2-65.5172.1000111.5R750L683-R750 PolarHBondContact O-NH2 3.12Å
684F58.5Low82.4Confident194 Ų19450.6 Ų50.685%0.85127%0.266SS*.SBendtrans-134.9151178.8-65.9-86000111
685G64.8Low82.4Confident72 Ų7248.7 Ų48.774%0.74226%0.258SS*.SBendtrans100.7-172.2179.600000114.3
686K73.5Confident82.2Confident189 Ų18948.7 Ų48.782%0.82226%0.258SS*.  trans-90.2139.9166.6-68.5-177.4178.1-178.50108.6
687P74.6Confident82Confident66 Ų6654 Ų5443%0.42928%0.278SS..  trans-63.2139.4171.428.9-34.6000110.2P679 E680P679-P687 HydrophobicContact CB-CB 3.81Å; P679-P687 HydrophobicContact CB-CG 3.76Å; E680-P687 HydrophobicContact CG-CB 3.47Å; E680-P687 VanDerWaalsContact CG-CB 3.47Å; E680-P687 WeakPolarHBondContact OE1-CA 3.29Å
688K75.4Confident81.5Confident158 Ų15855.5 Ų55.569%0.68728%0.284SS*.  trans-100.7-26.8180-63.1176.9-176.9173.10113.3E680E680-K688 PolarHBondContact OE1-N 3.41Å
689F83.9Confident81.2Confident50 Ų5061.6 Ų61.622%0.21931%0.308CS..SBendtrans-131.9156.8-172.8-50.3-64000111.4E680E680-F689 PolarHBondContact N-O 3.34Å
690S88.9Confident80.8Confident5 Ų567.9 Ų67.94%0.03533%0.333CS..EExtended strand (participates in β ladder)trans-89.8146.4163.1-81.20000110.5D718 L723S690-D718 VanDerWaalsContact CB-OD2 3.28Å; S690-D718 WeakPolarHBondContact CB-OD2 3.38Å; S690-D718 PolarHBondContact N-O 3.34Å; S690-D718 PolarHBondContact OG-OD2 2.93Å; S690-L723 VanDerWaalsContact O-CD1 3.24Å; S690-L723 WeakPolarHBondContact O-CD1 3.27Å
691C91.1Very high80.9Confident0 Ų068 Ų680%034%0.34CS..EExtended strand (participates in β ladder)trans-125.2151.2177.3-59.40000110.3I677 G678 T707 L708 L748I677-C691 WeakPolarHBondContact CA-O 3.49Å; G678-C691 PolarHBondContact N-O 2.91Å; G678-C691 PolarHBondContact O-N 3.19Å; C691-T707 HydrophobicContact CB-CG2 4.04Å; C691-L708 CarbonylContact C-O 3.57Å; C691-L708 WeakPolarHBondContact CA-O 2.82Å; C691-L748 HydrophobicContact CB-CD1 3.67Å
692M94.4Very high81.5Confident0 Ų070.6 Ų70.60%036%0.358CS..EExtended strand (participates in β ladder)trans-107.8128.9171.6180-177.266.600108.6L623 L642 I675 E676 I677 L694 L708 L723 I726 A727L623-M692 HydrophobicContact CD1-CE 4.47Å; L642-M692 HydrophobicContact CD2-CE 4.2Å; I675-M692 HydrophobicContact CG2-CG 3.58Å; I675-M692 HydrophobicContact CG2-SD 4.07Å; E676-M692 CarbonylContact O-C 3.58Å; I677-M692 HydrophobicContact CG1-CB 4.23Å; I677-M692 HydrophobicContact CG1-CG 4.11Å; M692-L694 HydrophobicContact CE-CD1 4.12Å; M692-L694 HydrophobicContact CE-CD2 3.9Å; M692-L694 HydrophobicContact CE-CG 4.02Å; M692-L694 HydrophobicContact CG-CD2 4.16Å; M692-L694 HydrophobicContact SD-CD2 3.93Å; M692-L708 PolarHBondContact N-O 2.76Å; M692-L708 PolarHBondContact O-N 3.31Å; M692-L723 HydrophobicContact CB-CB 4.16Å; M692-L723 HydrophobicContact CB-CD1 4.3Å; M692-L723 HydrophobicContact CB-CD2 3.95Å; M692-L723 HydrophobicContact CB-CG 4.37Å; M692-I726 HydrophobicContact CE-CG2 3.8Å; M692-I726 HydrophobicContact SD-CB 4.41Å; M692-I726 HydrophobicContact SD-CG2 4.08Å; M692-A727 HydrophobicContact SD-CB 4.09Å
693R92.9Very high82.1Confident2 Ų270.2 Ų70.21%0.00836%0.361CS..EExtended strand (participates in β ladder)trans-113.6109.5178.2-175.6172.6-78.5175.5-12.1110.7I675 E676 H695 F705 H706 T707 L748 E749I675-R693 WeakPolarHBondContact CA-O 3.48Å; E676-R693 HydrophobicContact CB-CB 4.33Å; E676-R693 PolarHBondContact N-O 2.99Å; E676-R693 PolarHBondContact O-N 3.37Å; R693-H695 WeakPolarHBondContact CD-NE2 3.31Å; R693-F705 VanDerWaalsContact CD-CD2 3.46Å; R693-F705 HydrophobicContact CG-CB 3.7Å; R693-F705 HydrophobicContact CG-CD2 3.75Å; R693-F705 HydrophobicContact CG-CG 3.82Å; R693-F705 VanDerWaalsContact CZ-CE2 3.49Å; R693-H706 CarbonylContact C-O 3.58Å; R693-H706 VanDerWaalsContact CA-O 3.23Å; R693-H706 WeakPolarHBondContact CA-O 3.31Å; R693-T707 PolarHBondContact NE-OG1 3.02Å; R693-T707 PolarHBondContact NH2-OG1 3.08Å; R693-L748 HydrophobicContact CB-CD2 4.21Å; R693-E749 PolarHBondContact NH1-O 3Å
694L93.6Very high83.3Confident0 Ų065.8 Ų65.80%034%0.336CS..EExtended strand (participates in β ladder)trans-87.5103.8177.4-58.9179.4000108.7L642 Y649 L672 I675 M692 F705 H706 L708 L730L642-L694 HydrophobicContact CD1-CD1 4.25Å; Y649-L694 HydrophobicContact CD2-CD1 4.39Å; Y649-L694 HydrophobicContact CE2-CD1 4.01Å; L672-L694 HydrophobicContact CD1-CB 4.03Å; L672-L694 HydrophobicContact CD1-CD2 4.33Å; I675-L694 HydrophobicContact CB-CD2 4.44Å; I675-L694 HydrophobicContact CD1-CD2 3.89Å; I675-L694 HydrophobicContact CG1-CD2 3.78Å; I675-L694 HydrophobicContact CG2-CD2 4.03Å; M692-L694 HydrophobicContact CE-CD1 4.12Å; M692-L694 HydrophobicContact CE-CD2 3.9Å; M692-L694 HydrophobicContact CE-CG 4.02Å; M692-L694 HydrophobicContact CG-CD2 4.16Å; M692-L694 HydrophobicContact SD-CD2 3.93Å; L694-F705 CarbonylContact O-C 3.55Å; L694-F705 WeakPolarHBondContact O-CA 3.45Å; L694-F705 VanDerWaalsContact O-CB 3.32Å; L694-F705 WeakPolarHBondContact O-CB 3.49Å; L694-H706 PolarHBondContact N-O 3.42Å; L694-H706 PolarHBondContact O-N 2.89Å; L694-H706 VanDerWaalsContact O-N 3.07Å; L694-L708 HydrophobicContact CD1-CD1 4.4Å; L694-L730 HydrophobicContact CD1-CD1 4.39Å; L694-L730 HydrophobicContact CD2-CD1 3.75Å
695H92.3Very high84.8Confident17 Ų1757.1 Ų57.18%0.07930%0.299CS..EExtended strand (participates in β ladder)trans-86.5132175.7-67.1-111.8000110.2E673 K674 E676 R693 F705E673-H695 PolarHBondContact N-O 2.88Å; K674-H695 VanDerWaalsContact CE-CG 3.45Å; K674-H695 WeakPolarHBondContact CE-ND1 3.47Å; K674-H695 HydrophobicContact CG-CB 3.67Å; K674-H695 PolarHBondContact O-N 3.47Å; E676-H695 IonicContact OE1-NE2 2.86Å; E676-H695 IonicContact OE2-CD2 2.7Å; E676-H695 IonicContact OE2-CE1 3.7Å; E676-H695 IonicContact OE2-NE2 3.54Å; E676-H695 PolarHBondContact OE2-NE2 3.36Å; R693-H695 WeakPolarHBondContact CD-NE2 3.31Å; H695-F705 HydrophobicContact CB-CB 4.48Å; H695-F705 AromaticContact CE1-CD1 3.82Å; H695-F705 AromaticContact ND1-CD1 3.81Å
696Y92.3Very high86.1Confident0 Ų053.8 Ų53.80%026%0.264CS..EExtended strand (participates in β ladder)trans-137.6156.3-177.773.3-85.9000112.7Y649 Q665 L667 D671 Y704 H706 H756 I759Y649-Y696 WeakPolarHBondContact OH-CB 3.46Å; Q665-Y696 PolarHBondContact NE2-OH 3.41Å; L667-Y696 HydrophobicContact CD1-CD1 4.13Å; L667-Y696 HydrophobicContact CD1-CD2 3.95Å; L667-Y696 HydrophobicContact CD1-CE1 4.16Å; L667-Y696 HydrophobicContact CD1-CE2 3.98Å; L667-Y696 HydrophobicContact CD1-CG 4.02Å; L667-Y696 HydrophobicContact CD2-CD2 3.4Å; L667-Y696 VanDerWaalsContact CD2-CD2 3.4Å; L667-Y696 HydrophobicContact CD2-CE2 3.54Å; L667-Y696 HydrophobicContact CD2-CG 4.18Å; L667-Y696 HydrophobicContact CG-CD2 4.34Å; L667-Y696 HydrophobicContact CG-CE2 4.44Å; D671-Y696 CarbonylContact O-C 3.6Å; D671-Y696 VanDerWaalsContact O-CA 3.31Å; D671-Y696 WeakPolarHBondContact O-CA 3.49Å; Y696-Y704 HydrophobicContact CE2-CG 4.24Å; Y696-Y704 VanDerWaalsContact CZ-CB 3.41Å; Y696-Y704 PolarHBondContact N-O 2.97Å; Y696-H706 AromaticContact CD1-CD2 3.97Å; Y696-H706 AromaticContact CD1-NE2 3.97Å; Y696-H706 AromaticContact CE1-CD2 3.65Å; Y696-H706 AromaticContact CE1-NE2 3.28Å; Y696-H706 VanDerWaalsContact CE1-NE2 3.28Å; Y696-H706 WeakPolarHBondContact CE1-NE2 3.34Å; Y696-H706 AromaticContact CZ-NE2 3.86Å; Y696-H756 AromaticContact CE1-ND1 3.93Å; Y696-H756 AromaticContact CZ-ND1 3.84Å; Y696-H756 PolarHBondContact OH-ND1 3.39Å; Y696-I759 HydrophobicContact CE2-CD1 4.35Å
697R88.9Confident86.9Confident112 Ų11244.8 Ų44.842%0.42322%0.224SC..EExtended strand (participates in β ladder)trans-91142.3174.1-166.8173.1-61.5162.95.9110.3D671 E673D671-R697 HydrophobicContact CB-CB 4.34Å; D671-R697 PolarHBondContact O-N 3.19Å; E673-R697 HydrophobicContact CG-CB 4.21Å; E673-R697 IonicContact OE1-CZ 3.2Å; E673-R697 VanDerWaalsContact OE1-CZ 3.23Å; E673-R697 IonicContact OE1-NE 3.01Å; E673-R697 PolarHBondContact OE1-NE 3.42Å; E673-R697 IonicContact OE1-NH2 2.72Å; E673-R697 PolarHBondContact OE1-NH2 2.89Å
698Y84Confident87.7Confident35 Ų3541.6 Ų41.614%0.13720%0.204CC..EExtended strand (participates in β ladder)trans-145.3129.6173.5-178.3-116.4000110.6E700 A701 Y704 E757 I759Y698-E700 PolarHBondContact O-N 2.91Å; Y698-A701 PolarHBondContact N-O 2.73Å; Y698-A701 PolarHBondContact O-N 2.94Å; Y698-Y704 HydrophobicContact CD1-CE1 4.27Å; Y698-Y704 HydrophobicContact CD1-CE2 4.39Å; Y698-Y704 AromaticContact CD1-CZ 4Å; Y698-E757 HydrophobicContact CE1-CB 4.06Å; Y698-E757 HydrophobicContact CE1-CG 4.27Å; Y698-E757 PolarHBondContact OH-OE2 3.35Å; Y698-I759 HydrophobicContact CD2-CD1 3.6Å; Y698-I759 HydrophobicContact CD2-CG1 4.08Å; Y698-I759 HydrophobicContact CE2-CB 4.42Å; Y698-I759 HydrophobicContact CE2-CD1 3.66Å; Y698-I759 HydrophobicContact CE2-CG1 3.58Å; Y698-I759 HydrophobicContact CE2-CG2 4.21Å; Y698-I759 HydrophobicContact CG-CD1 4.41Å
699K82.1Confident88.4Confident135 Ų13535.2 Ų35.259%0.58718%0.176SC*.THydrogen-bonded Turntrans48.548.7-172.7-64.5167.4174.71630111.4A701 E757K699-A701 PolarHBondContact O-N 3.43Å; K699-E757 IonicContact NZ-OE1 3.91Å; K699-E757 PolarHBondContact NZ-OE1 3.48Å; K699-E757 IonicContact NZ-OE2 2.67Å; K699-E757 PolarHBondContact NZ-OE2 2.72Å
700E79.1Confident88.5Confident186 Ų18633.1 Ų33.187%0.86917%0.167SC*.THydrogen-bonded Turntrans60.7-8.9-173.9-56.8-173.6156.900116.6Y698Y698-E700 PolarHBondContact O-N 2.91Å
701A83.2Confident88.1Confident36 Ų3635.1 Ų35.130%0.29818%0.179SC..EExtended strand (participates in β ladder)trans-87.1132.717800000112.3Y698 K699 Y704Y698-A701 PolarHBondContact N-O 2.73Å; Y698-A701 PolarHBondContact O-N 2.94Å; K699-A701 PolarHBondContact O-N 3.43Å; A701-Y704 HydrophobicContact CB-CE2 4.23Å; A701-Y704 WeakPolarHBondContact O-CE2 3.49Å
702S84.4Confident87.4Confident64 Ų6438 Ų3845%0.44819%0.194SC..EExtended strand (participates in β ladder)trans-87.4173.7171.858.70000112.3E673 K754E673-S702 WeakPolarHBondContact OE2-CB 3.45Å; S702-K754 PolarHBondContact O-NZ 2.84Å
703G82.8Confident86.1Confident31 Ų3149.6 Ų49.632%0.3224%0.237SC..EExtended strand (participates in β ladder)trans90.921.3179.100000114.9K754G703-K754 WeakPolarHBondContact O-CG 3.28Å; G703-K754 PolarHBondContact O-N 2.92Å
704Y88.8Confident85Confident29 Ų2952.4 Ų52.411%0.11425%0.252CS..EExtended strand (participates in β ladder)trans-98.5139.9161-57.3-97.5000108.6Y696 Y698 A701 K754Y696-Y704 HydrophobicContact CE2-CG 4.24Å; Y696-Y704 VanDerWaalsContact CZ-CB 3.41Å; Y696-Y704 PolarHBondContact N-O 2.97Å; Y698-Y704 HydrophobicContact CD1-CE1 4.27Å; Y698-Y704 HydrophobicContact CD1-CE2 4.39Å; Y698-Y704 AromaticContact CD1-CZ 4Å; A701-Y704 HydrophobicContact CB-CE2 4.23Å; A701-Y704 WeakPolarHBondContact O-CE2 3.49Å; Y704-K754 HydrophobicContact CD1-CB 3.47Å; Y704-K754 VanDerWaalsContact CD1-CB 3.47Å; Y704-K754 HydrophobicContact CD1-CD 4.35Å; Y704-K754 HydrophobicContact CD2-CD 4.1Å; Y704-K754 HydrophobicContact CE1-CB 3.44Å; Y704-K754 VanDerWaalsContact CE1-CB 3.44Å; Y704-K754 HydrophobicContact CE1-CD 4.02Å; Y704-K754 HydrophobicContact CE1-CG 4.4Å; Y704-K754 HydrophobicContact CE2-CD 3.73Å; Y704-K754 HydrophobicContact CG-CB 4.07Å; Y704-K754 HydrophobicContact CG-CD 4.37Å
705F90.8Very high83.8Confident13 Ų1358 Ų586%0.05729%0.288CS..EExtended strand (participates in β ladder)trans-156.1145.1174.451.5-101.4000113.5R693 L694 H695 K751 S752 S753 H756R693-F705 VanDerWaalsContact CD-CD2 3.46Å; R693-F705 HydrophobicContact CG-CB 3.7Å; R693-F705 HydrophobicContact CG-CD2 3.75Å; R693-F705 HydrophobicContact CG-CG 3.82Å; R693-F705 VanDerWaalsContact CZ-CE2 3.49Å; L694-F705 CarbonylContact O-C 3.55Å; L694-F705 WeakPolarHBondContact O-CA 3.45Å; L694-F705 VanDerWaalsContact O-CB 3.32Å; L694-F705 WeakPolarHBondContact O-CB 3.49Å; H695-F705 HydrophobicContact CB-CB 4.48Å; H695-F705 AromaticContact CE1-CD1 3.82Å; H695-F705 AromaticContact ND1-CD1 3.81Å; F705-K751 HydrophobicContact CZ-CB 4.4Å; F705-K751 WeakPolarHBondContact CZ-O 3.15Å; F705-S752 WeakPolarHBondContact CZ-O 3.24Å; F705-S753 VanDerWaalsContact CZ-N 3.34Å; F705-S753 PolarHBondContact N-OG 2.85Å; F705-S753 VanDerWaalsContact O-CB 3.27Å; F705-S753 WeakPolarHBondContact O-CB 3.28Å; F705-S753 PolarHBondContact O-OG 3.07Å; F705-H756 PolarHBondContact O-CE1 3.33Å; F705-H756 VanDerWaalsContact O-CE1 3.28Å
706H90.4Very high82.8Confident1 Ų165.2 Ų65.21%0.00532%0.322CS..EExtended strand (participates in β ladder)trans-93.8134166.6-57.1-77.3000109.1Y653 Q665 R693 L694 Y696 L708 H756Y653-H706 AromaticContact CE2-ND1 3.89Å; Y653-H706 AromaticContact CZ-ND1 3.86Å; Y653-H706 PolarHBondContact OH-ND1 3.23Å; Q665-H706 PolarHBondContact OE1-CE1 2.86Å; Q665-H706 PolarHBondContact OE1-NE2 2.9Å; Q665-H706 VanDerWaalsContact OE1-NE2 3.17Å; R693-H706 CarbonylContact C-O 3.58Å; R693-H706 VanDerWaalsContact CA-O 3.23Å; R693-H706 WeakPolarHBondContact CA-O 3.31Å; L694-H706 PolarHBondContact N-O 3.42Å; L694-H706 PolarHBondContact O-N 2.89Å; L694-H706 VanDerWaalsContact O-N 3.07Å; Y696-H706 AromaticContact CD1-CD2 3.97Å; Y696-H706 AromaticContact CD1-NE2 3.97Å; Y696-H706 AromaticContact CE1-CD2 3.65Å; Y696-H706 AromaticContact CE1-NE2 3.28Å; Y696-H706 VanDerWaalsContact CE1-NE2 3.28Å; Y696-H706 WeakPolarHBondContact CE1-NE2 3.34Å; Y696-H706 AromaticContact CZ-NE2 3.86Å; H706-L708 HydrophobicContact CB-CD1 4.35Å; H706-L708 HydrophobicContact CB-CD2 4.32Å; H706-L708 HydrophobicContact CB-CG 4.15Å; H706-H756 AromaticContact CE1-CE1 3.46Å; H706-H756 PolarHBondContact CE1-CE1 3.03Å; H706-H756 VanDerWaalsContact CE1-CE1 3.46Å; H706-H756 AromaticContact CE1-ND1 3.4Å; H706-H756 PolarHBondContact CE1-ND1 3.43Å; H706-H756 AromaticContact ND1-CE1 3.57Å; H706-H756 AromaticContact ND1-ND1 3.96Å; H706-H756 AromaticContact ND1-NE2 3.95Å; H706-H756 AromaticContact NE2-ND1 3.98Å
707T90.8Very high82.3Confident0 Ų070.1 Ų70.10%035%0.345CS..EExtended strand (participates in β ladder)trans-110.2107.4175.1-49.50000108.4D625 C626 C691 R693 L748D625-T707 VanDerWaalsContact OD1-O 3.08Å; C626-T707 WeakPolarHBondContact CA-O 3.4Å; C626-T707 HydrophobicContact CB-CG2 3.94Å; C626-T707 WeakPolarHBondContact CB-O 3.47Å; C626-T707 PolarHBondContact N-O 3.23Å; C691-T707 HydrophobicContact CB-CG2 4.04Å; R693-T707 PolarHBondContact NE-OG1 3.02Å; R693-T707 PolarHBondContact NH2-OG1 3.08Å; T707-L748 HydrophobicContact CG2-CD1 4.43Å
708L91.1Very high81.8Confident0 Ų067.8 Ų67.80%034%0.341CS..EExtended strand (participates in β ladder)trans-121.9149.5-169.2-54.3176.6000111.5L623 I624 V640 C691 M692 L694 H706L623-L708 HydrophobicContact CB-CB 4.4Å; L623-L708 HydrophobicContact CD1-CB 4.08Å; L623-L708 HydrophobicContact CD1-CD1 3.81Å; I624-L708 CarbonylContact O-C 3.52Å; I624-L708 WeakPolarHBondContact O-CA 3.34Å; V640-L708 HydrophobicContact CB-CD2 4.28Å; V640-L708 HydrophobicContact CG1-CD2 4Å; V640-L708 HydrophobicContact CG2-CD2 4.22Å; C691-L708 CarbonylContact C-O 3.57Å; C691-L708 WeakPolarHBondContact CA-O 2.82Å; M692-L708 PolarHBondContact N-O 2.76Å; M692-L708 PolarHBondContact O-N 3.31Å; L694-L708 HydrophobicContact CD1-CD1 4.4Å; H706-L708 HydrophobicContact CB-CD1 4.35Å; H706-L708 HydrophobicContact CB-CD2 4.32Å; H706-L708 HydrophobicContact CB-CG 4.15Å
709R89.7Confident81.8Confident24 Ų2466.3 Ų66.39%0.09134%0.336CS..EExtended strand (participates in β ladder)trans-126.2161.3170.773.4174.8171.282.2-6.8113.3L623 I624 C626 D637L623-R709 CarbonylContact C-O 3.59Å; L623-R709 WeakPolarHBondContact CA-O 3.42Å; L623-R709 WeakPolarHBondContact CB-O 3.4Å; I624-R709 HydrophobicContact CB-CG 4.05Å; I624-R709 HydrophobicContact CG2-CG 4.36Å; I624-R709 PolarHBondContact N-O 3.27Å; I624-R709 PolarHBondContact O-N 2.88Å; C626-R709 WeakPolarHBondContact SG-CD 3.31Å; C626-R709 WeakPolarHBondContact SG-CG 3.3Å; D637-R709 IonicContact OD1-CZ 3.8Å; D637-R709 IonicContact OD1-NH2 3.81Å; D637-R709 PolarHBondContact OD1-NH2 3.23Å; D637-R709 IonicContact OD2-CZ 2.98Å; D637-R709 IonicContact OD2-NH2 3.28Å; D637-R709 PolarHBondContact OD2-NH2 3.36Å
710A86.6Confident82.1Confident5 Ų562.3 Ų62.34%0.04132%0.319CS..EExtended strand (participates in β ladder)trans-73.8154.5173.900000112.4M712 T722 L723A710-M712 HydrophobicContact CB-CG 4.47Å; A710-M712 HydrophobicContact CB-SD 3.73Å; A710-M712 PolarHBondContact O-N 2.95Å; A710-T722 HydrophobicContact CB-CG2 3.97Å; A710-L723 HydrophobicContact CB-CD2 4.39Å; A710-L723 HydrophobicContact CB-CG 4.35Å
711V80.8Confident82.4Confident47 Ų4759.3 Ų59.329%0.28531%0.309SS..  trans-92.681.2178.8-167.70000110.5I624I624-V711 HydrophobicContact CD1-CB 4.34Å; I624-V711 HydrophobicContact CD1-CG1 4Å; I624-V711 HydrophobicContact CD1-CG2 3.8Å; I624-V711 HydrophobicContact CG1-CG2 3.96Å
712M76.2Confident82.4Confident62 Ų6260.8 Ų60.831%0.30531%0.314SS..  trans-75.9142.4-174.5-55.1-48.8-7800113A710 E717 G719A710-M712 HydrophobicContact CB-CG 4.47Å; A710-M712 HydrophobicContact CB-SD 3.73Å; A710-M712 PolarHBondContact O-N 2.95Å; M712-E717 HydrophobicContact CE-CB 3.47Å; M712-E717 VanDerWaalsContact CE-CB 3.47Å; M712-E717 HydrophobicContact CE-CG 4.21Å; M712-G719 VanDerWaalsContact SD-CA 3.59Å
713R67.9Low82.7Confident243 Ų24357.7 Ų57.792%0.91729%0.293SS*.SBendtrans-97.4-23173.5-70.4-169.8-177.6-171.42.9114.1
714N69.8Low83Confident61 Ų6158.1 Ų58.133%0.32629%0.286SS..SBendtrans-102.8122.2174.1-178.116.3000107.9E716 E717N714-E716 PolarHBondContact O-N 2.93Å; N714-E716 PolarHBondContact OD1-N 3.06Å; N714-E717 HydrophobicContact CB-CG 3.75Å; N714-E717 PolarHBondContact O-N 3.45Å
715P68.4Low82.9Confident116 Ų11660.3 Ų60.375%0.75331%0.305SS*.THydrogen-bonded Turntrans-72.1-4.7178.930.7-37.3000114.2
716E71.6Confident82.8Confident170 Ų17059.8 Ų59.879%0.79430%0.303SS*.THydrogen-bonded Turntrans-88.1-10.4174.5-57.9-179.1152.800113.1N714N714-E716 PolarHBondContact O-N 2.93Å; N714-E716 PolarHBondContact OD1-N 3.06Å
717E80.4Confident82.9Confident102 Ų10259.7 Ų59.748%0.47730%0.303SS..  trans-97.2128.2179.1-55.3-72.5165.900110.6M712 N714 G719M712-E717 HydrophobicContact CE-CB 3.47Å; M712-E717 VanDerWaalsContact CE-CB 3.47Å; M712-E717 HydrophobicContact CE-CG 4.21Å; N714-E717 HydrophobicContact CB-CG 3.75Å; N714-E717 PolarHBondContact O-N 3.45Å; E717-G719 VanDerWaalsContact C-N 3.32Å; E717-G719 PolarHBondContact O-N 2.92Å
718D79.9Confident82.8Confident64 Ų6463.6 Ų63.634%0.34232%0.321SS..  trans-79.5-15-178.987.6-30.1000113.8S690 K720S690-D718 VanDerWaalsContact CB-OD2 3.28Å; S690-D718 WeakPolarHBondContact CB-OD2 3.38Å; S690-D718 PolarHBondContact N-O 3.34Å; S690-D718 PolarHBondContact OG-OD2 2.93Å; D718-K720 VanDerWaalsContact OD1-CB 3.28Å; D718-K720 WeakPolarHBondContact OD1-CB 3.34Å; D718-K720 PolarHBondContact OD1-N 3.13Å
719G83.9Confident82.7Confident3 Ų367.2 Ų67.23%0.03134%0.339CS..  trans84.84.7179.400000116.1M712 E717 D721 T722 L723M712-G719 VanDerWaalsContact SD-CA 3.59Å; E717-G719 VanDerWaalsContact C-N 3.32Å; E717-G719 PolarHBondContact O-N 2.92Å; G719-D721 PolarHBondContact O-N 3.49Å; G719-T722 PolarHBondContact O-N 3.48Å; G719-L723 PolarHBondContact O-N 2.88Å
720K87.1Confident82.7Confident52 Ų5266.1 Ų66.123%0.22633%0.334CS..Hα-helixtrans-55-50.4-174.6-172.7-167.9168.2-168.70112.9I677 D718 T722 L723 Q724 E745I677-K720 HydrophobicContact CG2-CG 4.19Å; D718-K720 VanDerWaalsContact OD1-CB 3.28Å; D718-K720 WeakPolarHBondContact OD1-CB 3.34Å; D718-K720 PolarHBondContact OD1-N 3.13Å; K720-T722 VanDerWaalsContact C-N 3.27Å; K720-T722 PolarHBondContact O-N 2.9Å; K720-L723 CarbonylContact O-C 3.55Å; K720-L723 WeakPolarHBondContact O-CA 3.49Å; K720-L723 WeakPolarHBondContact O-CB 3.42Å; K720-L723 PolarHBondContact O-N 3.35Å; K720-Q724 PolarHBondContact O-N 3.33Å; K720-E745 VanDerWaalsContact CE-OE1 3.3Å; K720-E745 WeakPolarHBondContact CE-OE1 3.3Å; K720-E745 WeakPolarHBondContact CE-OE2 3.18Å; K720-E745 IonicContact NZ-OE1 3.52Å; K720-E745 PolarHBondContact NZ-OE1 3.25Å; K720-E745 IonicContact NZ-OE2 3.23Å; K720-E745 PolarHBondContact NZ-OE2 3.39Å
721D85.1Confident82.9Confident122 Ų12267.8 Ų67.865%0.65234%0.341SS*.Hα-helixtrans-61.3-35.4-173-62.4-7.3000112.6G719 Q724 C725G719-D721 PolarHBondContact O-N 3.49Å; D721-Q724 PolarHBondContact O-N 3.49Å; D721-C725 PolarHBondContact O-N 3.1Å; D721-C725 VanDerWaalsContact O-N 3.1Å; D721-C725 PolarHBondContact O-SG 3.31Å
722T84.7Confident83.4Confident67 Ų6770.8 Ų70.841%0.41136%0.355SS..Hα-helixtrans-66.5-38.9175.2-62.60000111.5A710 G719 K720 I726A710-T722 HydrophobicContact CB-CG2 3.97Å; G719-T722 PolarHBondContact O-N 3.48Å; K720-T722 VanDerWaalsContact C-N 3.27Å; K720-T722 PolarHBondContact O-N 2.9Å; T722-I726 HydrophobicContact CG2-CD1 4.35Å; T722-I726 WeakPolarHBondContact O-CD1 3.46Å; T722-I726 VanDerWaalsContact O-CG1 3.27Å; T722-I726 WeakPolarHBondContact O-CG1 3.25Å; T722-I726 PolarHBondContact O-N 3.44Å
723L89.4Confident84Confident0 Ų068.2 Ų68.20%034%0.343CS..Hα-helixtrans-72.1-36.2177.1-65.3173.4000112.2L623 S690 M692 A710 G719 K720 I726 A727L623-L723 HydrophobicContact CD2-CD2 4.22Å; S690-L723 VanDerWaalsContact O-CD1 3.24Å; S690-L723 WeakPolarHBondContact O-CD1 3.27Å; M692-L723 HydrophobicContact CB-CB 4.16Å; M692-L723 HydrophobicContact CB-CD1 4.3Å; M692-L723 HydrophobicContact CB-CD2 3.95Å; M692-L723 HydrophobicContact CB-CG 4.37Å; A710-L723 HydrophobicContact CB-CD2 4.39Å; A710-L723 HydrophobicContact CB-CG 4.35Å; G719-L723 PolarHBondContact O-N 2.88Å; K720-L723 CarbonylContact O-C 3.55Å; K720-L723 WeakPolarHBondContact O-CA 3.49Å; K720-L723 WeakPolarHBondContact O-CB 3.42Å; K720-L723 PolarHBondContact O-N 3.35Å; L723-I726 PolarHBondContact O-N 2.78Å; L723-A727 PolarHBondContact O-N 2.86Å
724Q89.2Confident85.1Confident39 Ų3957.2 Ų57.218%0.18230%0.301CS..Hα-helixtrans-60.2-48.4174.4-175.662.126.400111.1K720 D721 I726 A727 E728K720-Q724 PolarHBondContact O-N 3.33Å; D721-Q724 PolarHBondContact O-N 3.49Å; Q724-I726 VanDerWaalsContact C-N 3.26Å; Q724-I726 PolarHBondContact O-N 3.42Å; Q724-A727 PolarHBondContact O-N 3.47Å; Q724-A727 VanDerWaalsContact O-N 3.17Å; Q724-E728 WeakPolarHBondContact CG-OE1 3.45Å; Q724-E728 PolarHBondContact NE2-OE1 3.24Å; Q724-E728 WeakPolarHBondContact O-CG 3.13Å; Q724-E728 PolarHBondContact O-N 2.88Å
725C86.6Confident86.1Confident76 Ų7658.6 Ų58.651%0.51431%0.306SS..Hα-helixtrans-59.4-34.3176.4-64.40000113.2D721 M729D721-C725 PolarHBondContact O-N 3.1Å; D721-C725 VanDerWaalsContact O-N 3.1Å; D721-C725 PolarHBondContact O-SG 3.31Å; C725-M729 PolarHBondContact O-N 3.34Å; C725-M729 VanDerWaalsContact O-N 3.14Å
726I89.8Confident87Confident1 Ų157.2 Ų57.21%0.00530%0.304CS..Hα-helixtrans-70.8-44.9176.9-66.6166.5000110.5W621 L623 L642 M692 T722 L723 Q724 M729 L730W621-I726 HydrophobicContact CB-CD1 4.08Å; W621-I726 HydrophobicContact CD2-CD1 4.16Å; W621-I726 HydrophobicContact CD2-CG1 3.85Å; W621-I726 HydrophobicContact CD2-CG2 4.35Å; W621-I726 HydrophobicContact CE3-CG2 4.24Å; W621-I726 HydrophobicContact CG-CD1 3.74Å; W621-I726 HydrophobicContact CG-CG1 3.89Å; W621-I726 HydrophobicContact CZ2-CG1 4.26Å; W621-I726 HydrophobicContact CZ3-CG2 4.34Å; L623-I726 HydrophobicContact CD1-CD1 4.43Å; L623-I726 HydrophobicContact CD2-CD1 3.9Å; L642-I726 HydrophobicContact CD2-CG2 3.66Å; M692-I726 HydrophobicContact CE-CG2 3.8Å; M692-I726 HydrophobicContact SD-CB 4.41Å; M692-I726 HydrophobicContact SD-CG2 4.08Å; T722-I726 HydrophobicContact CG2-CD1 4.35Å; T722-I726 WeakPolarHBondContact O-CD1 3.46Å; T722-I726 VanDerWaalsContact O-CG1 3.27Å; T722-I726 WeakPolarHBondContact O-CG1 3.25Å; T722-I726 PolarHBondContact O-N 3.44Å; L723-I726 PolarHBondContact O-N 2.78Å; Q724-I726 VanDerWaalsContact C-N 3.26Å; Q724-I726 PolarHBondContact O-N 3.42Å; I726-M729 PolarHBondContact O-N 3.04Å; I726-L730 HydrophobicContact CG2-CD1 4.12Å; I726-L730 WeakPolarHBondContact O-CG 3.14Å; I726-L730 PolarHBondContact O-N 2.83Å
727A90.9Very high87.7Confident0 Ų052.5 Ų52.50%028%0.283CS..Hα-helixtrans-62.7-41.1177.500000112.2I675 I677 M692 L723 Q724 L730 Q731 I743I675-A727 HydrophobicContact CD1-CB 3.87Å; I675-A727 HydrophobicContact CG2-CB 3.84Å; I677-A727 HydrophobicContact CD1-CB 3.84Å; M692-A727 HydrophobicContact SD-CB 4.09Å; L723-A727 PolarHBondContact O-N 2.86Å; Q724-A727 PolarHBondContact O-N 3.47Å; Q724-A727 VanDerWaalsContact O-N 3.17Å; A727-L730 WeakPolarHBondContact O-CB 3.34Å; A727-L730 PolarHBondContact O-N 3.09Å; A727-Q731 WeakPolarHBondContact O-CB 3.24Å; A727-Q731 PolarHBondContact O-N 3.26Å; A727-I743 HydrophobicContact CB-CD1 3.81Å; A727-I743 HydrophobicContact CB-CG1 4.17Å; A727-I743 HydrophobicContact CB-CG2 4.23Å
728E90.5Very high87.8Confident82 Ų8251 Ų5138%0.38330%0.295SS..Hα-helixtrans-64.7-40.7175.3-72.7170.5-175.700112Q724 Q731 I732 I743Q724-E728 WeakPolarHBondContact CG-OE1 3.45Å; Q724-E728 PolarHBondContact NE2-OE1 3.24Å; Q724-E728 WeakPolarHBondContact O-CG 3.13Å; Q724-E728 PolarHBondContact O-N 2.88Å; E728-Q731 PolarHBondContact O-N 3.48Å; E728-I732 WeakPolarHBondContact O-CB 3.37Å; E728-I732 WeakPolarHBondContact O-CD1 3.17Å; E728-I732 VanDerWaalsContact O-CG1 3.25Å; E728-I732 WeakPolarHBondContact O-CG1 3.14Å; E728-I732 PolarHBondContact O-N 3.14Å; E728-I743 HydrophobicContact CG-CD1 3.94Å
729M88.2Confident87.9Confident76 Ų7650.8 Ų50.837%0.37430%0.299SS..Hα-helixtrans-67.5-36.1176.3-164.8176.2-63.300112.6W621 L644 C725 I726 T733W621-M729 HydrophobicContact CH2-CB 4.35Å; W621-M729 HydrophobicContact CH2-CG 4.33Å; W621-M729 HydrophobicContact CH2-SD 3.67Å; W621-M729 HydrophobicContact CZ2-CB 4.4Å; W621-M729 HydrophobicContact CZ2-CE 4.13Å; W621-M729 HydrophobicContact CZ2-CG 4.5Å; W621-M729 HydrophobicContact CZ2-SD 3.54Å; W621-M729 VanDerWaalsContact CZ2-SD 3.54Å; L644-M729 HydrophobicContact CD2-CB 4.48Å; L644-M729 HydrophobicContact CD2-CG 3.97Å; C725-M729 PolarHBondContact O-N 3.34Å; C725-M729 VanDerWaalsContact O-N 3.14Å; I726-M729 PolarHBondContact O-N 3.04Å; M729-T733 WeakPolarHBondContact O-CB 3.19Å; M729-T733 PolarHBondContact O-N 3.5Å; M729-T733 VanDerWaalsContact O-N 3.09Å; M729-T733 PolarHBondContact O-OG1 3.24Å
730L89.8Confident88.1Confident0 Ų055.2 Ų55.20%032%0.322CS..Hα-helixtrans-62.4-45.6170.1-76.1163.1000111.2L644 Y649 L669 L672 I675 L694 I726 A727 T733 K734L644-L730 HydrophobicContact CD1-CD2 3.7Å; L644-L730 HydrophobicContact CD2-CD2 4.09Å; L644-L730 HydrophobicContact CD2-CG 4.35Å; L644-L730 HydrophobicContact CG-CD2 4.41Å; Y649-L730 HydrophobicContact CG-CD2 4.48Å; L669-L730 HydrophobicContact CD2-CD2 3.97Å; L672-L730 HydrophobicContact CD2-CB 4.46Å; L672-L730 HydrophobicContact CD2-CD2 4.47Å; I675-L730 HydrophobicContact CD1-CB 3.9Å; I675-L730 HydrophobicContact CD1-CD1 3.93Å; L694-L730 HydrophobicContact CD1-CD1 4.39Å; L694-L730 HydrophobicContact CD2-CD1 3.75Å; I726-L730 HydrophobicContact CG2-CD1 4.12Å; I726-L730 WeakPolarHBondContact O-CG 3.14Å; I726-L730 PolarHBondContact O-N 2.83Å; A727-L730 WeakPolarHBondContact O-CB 3.34Å; A727-L730 PolarHBondContact O-N 3.09Å; L730-T733 PolarHBondContact O-N 2.98Å; L730-K734 PolarHBondContact O-N 3.22Å
731Q91.4Very high88.3Confident41 Ų4152.8 Ų52.819%0.19231%0.311CS..Hα-helixtrans-63.4-51.8179.2-171.9-17916.800112A727 E728 T733 K734 Q735 D740 V741 I743A727-Q731 WeakPolarHBondContact O-CB 3.24Å; A727-Q731 PolarHBondContact O-N 3.26Å; E728-Q731 PolarHBondContact O-N 3.48Å; Q731-T733 PolarHBondContact O-N 3.45Å; Q731-K734 PolarHBondContact O-N 3.35Å; Q731-Q735 HydrophobicContact CG-CG 4.36Å; Q731-Q735 WeakPolarHBondContact O-CB 3.39Å; Q731-Q735 VanDerWaalsContact O-CG 3.31Å; Q731-Q735 WeakPolarHBondContact O-CG 3.3Å; Q731-Q735 PolarHBondContact O-N 3.16Å; Q731-D740 WeakPolarHBondContact CG-OD1 3.42Å; Q731-D740 PolarHBondContact NE2-OD1 3.02Å; Q731-V741 HydrophobicContact CB-CG1 3.97Å; Q731-V741 HydrophobicContact CG-CG1 4.01Å; Q731-V741 WeakPolarHBondContact CG-O 3.28Å; Q731-V741 PolarHBondContact NE2-O 3.3Å; Q731-I743 HydrophobicContact CB-CD1 4.18Å; Q731-I743 VanDerWaalsContact OE1-CD1 3.28Å
732I90.8Very high88.7Confident109 Ų10949.9 Ų49.956%0.55930%0.299SS*.Hα-helixtrans-59-37.8178.9-67.7163.5000110.9E728 Q735 A736E728-I732 WeakPolarHBondContact O-CB 3.37Å; E728-I732 WeakPolarHBondContact O-CD1 3.17Å; E728-I732 VanDerWaalsContact O-CG1 3.25Å; E728-I732 WeakPolarHBondContact O-CG1 3.14Å; E728-I732 PolarHBondContact O-N 3.14Å; I732-Q735 PolarHBondContact O-N 2.91Å; I732-A736 PolarHBondContact O-N 3.39Å
733T89.2Confident89.1Confident9 Ų948.6 Ų48.66%0.05529%0.289CS..Hα-helixtrans-69.9-42.9178.3-56.20000112.1H618 L644 S645 L669 M729 L730 Q731 Q735 A736 M737H618-T733 VanDerWaalsContact ND1-CG2 3.34Å; H618-T733 WeakPolarHBondContact ND1-CG2 3.46Å; H618-T733 PolarHBondContact ND1-OG1 3.32Å; L644-T733 HydrophobicContact CD1-CG2 4.32Å; S645-T733 WeakPolarHBondContact O-CG2 3.45Å; L669-T733 HydrophobicContact CD1-CG2 3.61Å; M729-T733 WeakPolarHBondContact O-CB 3.19Å; M729-T733 PolarHBondContact O-N 3.5Å; M729-T733 VanDerWaalsContact O-N 3.09Å; M729-T733 PolarHBondContact O-OG1 3.24Å; L730-T733 PolarHBondContact O-N 2.98Å; Q731-T733 PolarHBondContact O-N 3.45Å; T733-Q735 VanDerWaalsContact C-N 3.35Å; T733-A736 WeakPolarHBondContact O-CB 3.3Å; T733-A736 PolarHBondContact O-N 3.19Å; T733-M737 PolarHBondContact O-N 3.24Å
734K90.6Very high89.2Confident11 Ų1151.6 Ų51.65%0.04831%0.305CS..Hα-helixtrans-64.4-40173.9-162.6-168.4172.3124.30111.4L669 E670 L672 L730 Q731 A736 M737 G738 S739 D740 V741L669-K734 HydrophobicContact CB-CG 4.33Å; L669-K734 VanDerWaalsContact O-CD 3.31Å; L669-K734 WeakPolarHBondContact O-CD 3.34Å; L669-K734 VanDerWaalsContact O-CE 3.25Å; L669-K734 WeakPolarHBondContact O-CE 3.43Å; L669-K734 PolarHBondContact O-NZ 2.84Å; E670-K734 PolarHBondContact O-NZ 3.3Å; L672-K734 PolarHBondContact O-NZ 3.21Å; L730-K734 PolarHBondContact O-N 3.22Å; Q731-K734 PolarHBondContact O-N 3.35Å; K734-A736 VanDerWaalsContact C-N 3.27Å; K734-A736 PolarHBondContact O-N 3.23Å; K734-M737 WeakPolarHBondContact O-CA 3.28Å; K734-M737 VanDerWaalsContact O-CB 3.31Å; K734-M737 WeakPolarHBondContact O-CB 3.28Å; K734-M737 PolarHBondContact O-N 3.28Å; K734-G738 PolarHBondContact O-N 3.18Å; K734-S739 CarbonylContact C-O 3.5Å; K734-S739 VanDerWaalsContact CG-O 3.28Å; K734-S739 WeakPolarHBondContact CG-O 3.48Å; K734-S739 PolarHBondContact O-N 2.89Å; K734-D740 VanDerWaalsContact CE-O 3.31Å; K734-D740 WeakPolarHBondContact CE-O 3.48Å; K734-V741 HydrophobicContact CB-CG1 4.18Å; K734-V741 HydrophobicContact CD-CB 3.68Å; K734-V741 HydrophobicContact CD-CG1 3.8Å
735Q90.5Very high89.3Confident90 Ų9055.5 Ų55.542%0.42132%0.323SS..Hα-helixtrans-60.7-36.2175.5-75.2177.40.700112Q731 I732 T733 M737 G738 S739 D740Q731-Q735 HydrophobicContact CG-CG 4.36Å; Q731-Q735 WeakPolarHBondContact O-CB 3.39Å; Q731-Q735 VanDerWaalsContact O-CG 3.31Å; Q731-Q735 WeakPolarHBondContact O-CG 3.3Å; Q731-Q735 PolarHBondContact O-N 3.16Å; I732-Q735 PolarHBondContact O-N 2.91Å; T733-Q735 VanDerWaalsContact C-N 3.35Å; Q735-M737 PolarHBondContact O-N 2.9Å; Q735-G738 WeakPolarHBondContact O-CA 3.46Å; Q735-G738 PolarHBondContact O-N 3.19Å; Q735-S739 VanDerWaalsContact CA-O 3.28Å; Q735-S739 WeakPolarHBondContact CA-O 3.4Å; Q735-S739 PolarHBondContact N-O 3.17Å; Q735-D740 HydrophobicContact CG-CB 4.45Å; Q735-D740 PolarHBondContact NE2-OD1 3Å
736A87.5Confident89.4Confident88 Ų8854.9 Ų54.973%0.72731%0.311SS*.Hα-helixtrans-66.8-20173.400000113.7I732 T733 K734 G738I732-A736 PolarHBondContact O-N 3.39Å; T733-A736 WeakPolarHBondContact O-CB 3.3Å; T733-A736 PolarHBondContact O-N 3.19Å; K734-A736 VanDerWaalsContact C-N 3.27Å; K734-A736 PolarHBondContact O-N 3.23Å; A736-G738 VanDerWaalsContact C-N 3.34Å
737M85.8Confident89.1Confident71 Ų7163.1 Ų63.135%0.3535%0.347SS..THydrogen-bonded Turntrans-85.2-4.8168.5-55.4169.867.800113.1L669 E670 T733 K734 Q735L669-M737 HydrophobicContact CB-CE 4.37Å; L669-M737 HydrophobicContact CB-SD 3.62Å; L669-M737 HydrophobicContact CD1-SD 3.74Å; L669-M737 HydrophobicContact CG-SD 4.32Å; E670-M737 HydrophobicContact CG-CE 4.12Å; T733-M737 PolarHBondContact O-N 3.24Å; K734-M737 WeakPolarHBondContact O-CA 3.28Å; K734-M737 VanDerWaalsContact O-CB 3.31Å; K734-M737 WeakPolarHBondContact O-CB 3.28Å; K734-M737 PolarHBondContact O-N 3.28Å; Q735-M737 PolarHBondContact O-N 2.9Å
738G82.6Confident88.8Confident70 Ų7063.5 Ų63.572%0.72235%0.349SS*.THydrogen-bonded Turntrans9116.3-179.500000115.6K734 Q735 A736K734-G738 PolarHBondContact O-N 3.18Å; Q735-G738 WeakPolarHBondContact O-CA 3.46Å; Q735-G738 PolarHBondContact O-N 3.19Å; A736-G738 VanDerWaalsContact C-N 3.34Å
739S83.4Confident88.4Confident60 Ų6063.2 Ų63.242%0.4235%0.348SS..  trans-132.4141.2174.9-73.80000111.7K734 Q735K734-S739 CarbonylContact C-O 3.5Å; K734-S739 VanDerWaalsContact CG-O 3.28Å; K734-S739 WeakPolarHBondContact CG-O 3.48Å; K734-S739 PolarHBondContact O-N 2.89Å; Q735-S739 VanDerWaalsContact CA-O 3.28Å; Q735-S739 WeakPolarHBondContact CA-O 3.4Å; Q735-S739 PolarHBondContact N-O 3.17Å
740D87.3Confident87.8Confident96 Ų9667.5 Ų67.551%0.51336%0.36SS..  trans-92161.6177.2-162.818.2000112.2Q731 K734 Q735Q731-D740 WeakPolarHBondContact CG-OD1 3.42Å; Q731-D740 PolarHBondContact NE2-OD1 3.02Å; K734-D740 VanDerWaalsContact CE-O 3.31Å; K734-D740 WeakPolarHBondContact CE-O 3.48Å; Q735-D740 HydrophobicContact CG-CB 4.45Å; Q735-D740 PolarHBondContact NE2-OD1 3Å
741V91.6Very high87.1Confident0 Ų073.4 Ų73.40%039%0.385CS..  trans-137.7120.3169.951.70000109.2L672 I675 Q731 K734 I743L672-V741 HydrophobicContact CD2-CG1 4.37Å; L672-V741 HydrophobicContact CD2-CG2 4.18Å; L672-V741 HydrophobicContact CG-CG2 4.07Å; I675-V741 HydrophobicContact CG1-CG2 4.11Å; Q731-V741 HydrophobicContact CB-CG1 3.97Å; Q731-V741 HydrophobicContact CG-CG1 4.01Å; Q731-V741 WeakPolarHBondContact CG-O 3.28Å; Q731-V741 PolarHBondContact NE2-O 3.3Å; K734-V741 HydrophobicContact CB-CG1 4.18Å; K734-V741 HydrophobicContact CD-CB 3.68Å; K734-V741 HydrophobicContact CD-CG1 3.8Å; V741-I743 PolarHBondContact O-N 3.2Å
742P92.3Very high86.4Confident62 Ų6274.9 Ų74.940%0.40340%0.4SS..  trans-73.7129.2-176.428.9-33.9000111.3K674 I675 I744K674-P742 HydrophobicContact CB-CG 3.89Å; I675-P742 PolarHBondContact N-O 3.35Å; P742-I744 HydrophobicContact CB-CG1 4.3Å
743I93.2Very high86Confident40 Ų4070.4 Ų70.421%0.20538%0.379CS..EExtended strand (participates in β ladder)trans-89.3125.7165.9-52.2174.2000107.8I675 I677 A727 E728 Q731 V741I675-I743 HydrophobicContact CB-CG1 4.49Å; I675-I743 CarbonylContact O-C 3.59Å; I675-I743 WeakPolarHBondContact O-CA 3.25Å; I677-I743 HydrophobicContact CD1-CG2 4.09Å; A727-I743 HydrophobicContact CB-CD1 3.81Å; A727-I743 HydrophobicContact CB-CG1 4.17Å; A727-I743 HydrophobicContact CB-CG2 4.23Å; E728-I743 HydrophobicContact CG-CD1 3.94Å; Q731-I743 HydrophobicContact CB-CD1 4.18Å; Q731-I743 VanDerWaalsContact OE1-CD1 3.28Å; V741-I743 PolarHBondContact O-N 3.2Å
744I93.1Very high85.7Confident63 Ų6374.1 Ų74.132%0.32339%0.394SS..EExtended strand (participates in β ladder)trans-126.1107.3-172.1-54.2176.5000109.6K674 I675 E676 I677 P742 K746K674-I744 HydrophobicContact CD-CD1 4.28Å; I675-I744 PolarHBondContact O-N 2.67Å; E676-I744 CarbonylContact C-O 3.59Å; E676-I744 WeakPolarHBondContact CA-O 3.43Å; E676-I744 HydrophobicContact CG-CB 4.42Å; I677-I744 PolarHBondContact N-O 2.97Å; P742-I744 HydrophobicContact CB-CG1 4.3Å; I744-K746 HydrophobicContact CG2-CB 4.46Å; I744-K746 HydrophobicContact CG2-CD 4.43Å; I744-K746 HydrophobicContact CG2-CG 4.29Å; I744-K746 PolarHBondContact O-N 3.44Å
745E89.9Confident85.1Confident121 Ų12179 Ų7957%0.56543%0.427SS*.EExtended strand (participates in β ladder)trans-73.2112.6167.4-70.9-160.4-153.500110.6I677 K720I677-E745 WeakPolarHBondContact O-CA 3.31Å; K720-E745 VanDerWaalsContact CE-OE1 3.3Å; K720-E745 WeakPolarHBondContact CE-OE1 3.3Å; K720-E745 WeakPolarHBondContact CE-OE2 3.18Å; K720-E745 IonicContact NZ-OE1 3.52Å; K720-E745 PolarHBondContact NZ-OE1 3.25Å; K720-E745 IonicContact NZ-OE2 3.23Å; K720-E745 PolarHBondContact NZ-OE2 3.39Å
746K88.2Confident84.5Confident63 Ų6376.3 Ų76.327%0.27441%0.414SS..  trans-155.9162171.770.3169.4-171.1-171.20111.6E676 I677 G678 I744 L748 E749E676-K746 VanDerWaalsContact OE1-CE 3.22Å; E676-K746 WeakPolarHBondContact OE1-CE 3.38Å; E676-K746 IonicContact OE1-NZ 2.61Å; E676-K746 PolarHBondContact OE1-NZ 3.26Å; E676-K746 WeakPolarHBondContact OE2-CE 3.47Å; E676-K746 IonicContact OE2-NZ 2.73Å; E676-K746 PolarHBondContact OE2-NZ 3.44Å; I677-K746 PolarHBondContact O-N 3.35Å; I677-K746 VanDerWaalsContact O-O 3.07Å; G678-K746 WeakPolarHBondContact CA-O 3.29Å; I744-K746 HydrophobicContact CG2-CB 4.46Å; I744-K746 HydrophobicContact CG2-CD 4.43Å; I744-K746 HydrophobicContact CG2-CG 4.29Å; I744-K746 PolarHBondContact O-N 3.44Å; K746-L748 PolarHBondContact O-N 3.13Å; K746-E749 IonicContact NZ-OE1 3.03Å; K746-E749 PolarHBondContact NZ-OE1 3.04Å
747K84.4Confident83.6Confident174 Ų17476.5 Ų76.576%0.75740%0.4SS*.PPolyproline II helixtrans-61123.1166.7-172.1175.3-176.7176.40109.9
748L85.6Confident82.5Confident8 Ų877.2 Ų77.24%0.04241%0.405CS..PPolyproline II helixtrans-67.1139.9-176.5-63179.7000111.7E676 C691 R693 T707 K746E676-L748 HydrophobicContact CB-CD2 3.86Å; C691-L748 HydrophobicContact CB-CD1 3.67Å; R693-L748 HydrophobicContact CB-CD2 4.21Å; T707-L748 HydrophobicContact CG2-CD1 4.43Å; K746-L748 PolarHBondContact O-N 3.13Å
749E80.5Confident81.2Confident75 Ų7576.1 Ų76.135%0.3538%0.382SS..PPolyproline II helixtrans-76.4134.3-179.3-70.7169.1-125.200111.1R693 K746 K751R693-E749 PolarHBondContact NH1-O 3Å; K746-E749 IonicContact NZ-OE1 3.03Å; K746-E749 PolarHBondContact NZ-OE1 3.04Å; E749-K751 HydrophobicContact CB-CD 4.34Å; E749-K751 PolarHBondContact O-N 3.23Å; E749-K751 WeakPolarHBondContact OE2-CE 3.48Å; E749-K751 IonicContact OE2-NZ 2.69Å; E749-K751 PolarHBondContact OE2-NZ 3.19Å
750R76.1Confident79.7Confident166 Ų16677.9 Ų77.963%0.62639%0.386SS*.SBendtrans-73.876.3173.1-70.3178.2175.3169.7-6110.5P681 T682 L683P681-R750 HydrophobicContact CB-CG 4.3Å; T682-R750 PolarHBondContact O-NE 3.43Å; T682-R750 PolarHBondContact O-NH2 3.16Å; L683-R750 PolarHBondContact O-NH2 3.12Å
751K75.8Confident77.3Confident125 Ų12575 Ų7554%0.54338%0.379SS..  trans-136.6141.7172.9-65.6170.2179.41660106.8F705 E749F705-K751 HydrophobicContact CZ-CB 4.4Å; F705-K751 WeakPolarHBondContact CZ-O 3.15Å; E749-K751 HydrophobicContact CB-CD 4.34Å; E749-K751 PolarHBondContact O-N 3.23Å; E749-K751 WeakPolarHBondContact OE2-CE 3.48Å; E749-K751 IonicContact OE2-NZ 2.69Å; E749-K751 PolarHBondContact OE2-NZ 3.19Å
752S75.1Confident74.8Confident72 Ų7283.7 Ų83.750%0.50342%0.424SS..PPolyproline II helixtrans-80.315616757.70000110F705F705-S752 WeakPolarHBondContact CZ-O 3.24Å
753S82.9Confident71.9Confident15 Ų1591.8 Ų91.811%0.10545%0.446CS..PPolyproline II helixtrans-63.9160.9168.2-175.40000111.6D627 F705 H756D627-S753 PolarHBondContact OD2-N 3.43Å; D627-S753 VanDerWaalsContact OD2-N 3.08Å; F705-S753 VanDerWaalsContact CZ-N 3.34Å; F705-S753 PolarHBondContact N-OG 2.85Å; F705-S753 VanDerWaalsContact O-CB 3.27Å; F705-S753 WeakPolarHBondContact O-CB 3.28Å; F705-S753 PolarHBondContact O-OG 3.07Å; S753-H756 PolarHBondContact OG-CE1 3.18Å
754K82.9Confident69.3Low86 Ų8694.9 Ų94.937%0.37447%0.471SS..PPolyproline II helixtrans-61.6149153.7-74.5174177.8175.60109.5S702 G703 Y704 H756S702-K754 PolarHBondContact O-NZ 2.84Å; G703-K754 WeakPolarHBondContact O-CG 3.28Å; G703-K754 PolarHBondContact O-N 2.92Å; Y704-K754 HydrophobicContact CD1-CB 3.47Å; Y704-K754 VanDerWaalsContact CD1-CB 3.47Å; Y704-K754 HydrophobicContact CD1-CD 4.35Å; Y704-K754 HydrophobicContact CD2-CD 4.1Å; Y704-K754 HydrophobicContact CE1-CB 3.44Å; Y704-K754 VanDerWaalsContact CE1-CB 3.44Å; Y704-K754 HydrophobicContact CE1-CD 4.02Å; Y704-K754 HydrophobicContact CE1-CG 4.4Å; Y704-K754 HydrophobicContact CE2-CD 3.73Å; Y704-K754 HydrophobicContact CG-CB 4.07Å; Y704-K754 HydrophobicContact CG-CD 4.37Å; K754-H756 PolarHBondContact O-N 3.34Å
755P77.9Confident66.4Low114 Ų114100.5 Ų100.574%0.7450%0.496SS*.PPolyproline II helixtrans-59.4132.3-178.224.5-34.3000111.4E757P755-E757 PolarHBondContact O-N 2.64Å
756H77.8Confident63.6Low34 Ų34102.3 Ų102.316%0.15751%0.51CS..  trans-76.6115179.4-59.6-73.3000109.7Q663 Y696 F705 H706 S753 K754Q663-H756 PolarHBondContact NE2-O 3.31Å; Y696-H756 AromaticContact CE1-ND1 3.93Å; Y696-H756 AromaticContact CZ-ND1 3.84Å; Y696-H756 PolarHBondContact OH-ND1 3.39Å; F705-H756 PolarHBondContact O-CE1 3.33Å; F705-H756 VanDerWaalsContact O-CE1 3.28Å; H706-H756 AromaticContact CE1-CE1 3.46Å; H706-H756 PolarHBondContact CE1-CE1 3.03Å; H706-H756 VanDerWaalsContact CE1-CE1 3.46Å; H706-H756 AromaticContact CE1-ND1 3.4Å; H706-H756 PolarHBondContact CE1-ND1 3.43Å; H706-H756 AromaticContact ND1-CE1 3.57Å; H706-H756 AromaticContact ND1-ND1 3.96Å; H706-H756 AromaticContact ND1-NE2 3.95Å; H706-H756 AromaticContact NE2-ND1 3.98Å; S753-H756 PolarHBondContact OG-CE1 3.18Å; K754-H756 PolarHBondContact O-N 3.34Å
757E69.6Low61.3Low92 Ų92109.1 Ų109.143%0.4354%0.543SS..  trans-82147.8168.5-69-176.3-15000110.7Q665 Y698 K699 P755 I759Q665-E757 PolarHBondContact NE2-O 2.77Å; Y698-E757 HydrophobicContact CE1-CB 4.06Å; Y698-E757 HydrophobicContact CE1-CG 4.27Å; Y698-E757 PolarHBondContact OH-OE2 3.35Å; K699-E757 IonicContact NZ-OE1 3.91Å; K699-E757 PolarHBondContact NZ-OE1 3.48Å; K699-E757 IonicContact NZ-OE2 2.67Å; K699-E757 PolarHBondContact NZ-OE2 2.72Å; P755-E757 PolarHBondContact O-N 2.64Å; E757-I759 WeakPolarHBondContact O-CG1 3.41Å; E757-I759 PolarHBondContact O-N 3.32Å; E757-I759 VanDerWaalsContact O-N 3.08Å
758D61.5Low59.1Low85 Ų85103.5 Ų103.546%0.45554%0.535SS..  trans-69.1105.6172.3-73.9-47.1000111.4Q663 Y664 I760 G761Q663-D758 WeakPolarHBondContact CG-OD1 3.36Å; Y664-D758 PolarHBondContact N-OD1 2.79Å; D758-I760 VanDerWaalsContact C-N 3.27Å; D758-I760 PolarHBondContact O-N 3.1Å; D758-G761 PolarHBondContact O-N 2.96Å
759I56.7Low56.9Low48 Ų48109.4 Ų109.425%0.24658%0.576CS.*THydrogen-bonded Turntrans-72.1-22.1-171.3-59.8-176.9000112.3Q665 L667 Y696 Y698 E757Q665-I759 HydrophobicContact CG-CD1 4.38Å; Q665-I759 HydrophobicContact CG-CG1 4.16Å; L667-I759 HydrophobicContact CD2-CD1 3.32Å; L667-I759 HydrophobicContact CG-CD1 4.07Å; Y696-I759 HydrophobicContact CE2-CD1 4.35Å; Y698-I759 HydrophobicContact CD2-CD1 3.6Å; Y698-I759 HydrophobicContact CD2-CG1 4.08Å; Y698-I759 HydrophobicContact CE2-CB 4.42Å; Y698-I759 HydrophobicContact CE2-CD1 3.66Å; Y698-I759 HydrophobicContact CE2-CG1 3.58Å; Y698-I759 HydrophobicContact CE2-CG2 4.21Å; Y698-I759 HydrophobicContact CG-CD1 4.41Å; E757-I759 WeakPolarHBondContact O-CG1 3.41Å; E757-I759 PolarHBondContact O-N 3.32Å; E757-I759 VanDerWaalsContact O-N 3.08Å
760I51.8Low54.8Low97 Ų97112.5 Ų112.550%0.49759%0.594SS.*THydrogen-bonded Turntrans-12781.2158-55-178000108R666 D758R666-I760 HydrophobicContact CB-CD1 4.39Å; D758-I760 VanDerWaalsContact C-N 3.27Å; D758-I760 PolarHBondContact O-N 3.1Å
761G36.2Very low52.9Low36 Ų36109 Ų10937%0.37160%0.601SS.*  trans-60.3137.1168.700000110.9D758 R763D758-G761 PolarHBondContact O-N 2.96Å; G761-R763 PolarHBondContact O-N 3.47Å
762I40.2Very low51.1Low181 Ų181111.7 Ų111.793%0.92862%0.616SS**  trans-74.861.4173.4-50.2178.4000109.2
763R30.6Very low49.3Very low232 Ų232109.7 Ų109.788%0.87561%0.607SS**  trans-94.8131.5179.8-81.3-170.8168.9-169.5-2.5110.9G761 Q765G761-R763 PolarHBondContact O-N 3.47Å; R763-Q765 PolarHBondContact O-N 3.36Å
764S37.8Very low47Very low105 Ų105116.8 Ų116.873%0.73464%0.635SS**  trans-78.780.4-172-1800000112.8
765Q33.6Very low44.7Very low182 Ų182118.9 Ų118.985%0.8565%0.651SS**  trans-131.176.9165.5-77.9-166.4-28.300112.3R763R763-Q765 PolarHBondContact O-N 3.36Å
766N30.4Very low42.7Very low158 Ų158120.1 Ų120.185%0.84565%0.645SS**  trans-17192.4138.4-99.1-25.9000109.5G768N766-G768 VanDerWaalsContact C-N 3.25Å; N766-G768 PolarHBondContact O-N 3.3Å
767Q39.7Very low40.8Very low206 Ų206123.5 Ų123.596%0.96366%0.663SS**  trans-7880.7166.7-83-174.6-2600109.3
768G38Very low39.1Very low57 Ų57125.9 Ų125.959%0.58868%0.676SS**SBendtrans-162.8113.917500000110.8N766 L770N766-G768 VanDerWaalsContact C-N 3.25Å; N766-G768 PolarHBondContact O-N 3.3Å; G768-L770 PolarHBondContact O-N 3.33Å
769S40.3Very low37.9Very low131 Ų131125.2 Ų125.292%0.91668%0.678SS**SBendtrans65.425.7168.7-142.10000119.4
770L36.4Very low36.7Very low140 Ų140128.6 Ų128.673%0.73369%0.691SS**  trans-137.126.8170.4-146.179.3000116.5G768 Q772 G773G768-L770 PolarHBondContact O-N 3.33Å; L770-Q772 VanDerWaalsContact C-N 3.25Å; L770-Q772 PolarHBondContact O-N 3.26Å; L770-G773 PolarHBondContact O-N 3.14Å
771A35.4Very low35.8Very low93 Ų93130.1 Ų130.177%0.76969%0.694SS**Hα-helixtrans-62.7-29176.500000113.6
772Q38.9Very low35.8Very low182 Ų182132.4 Ų132.485%0.8570%0.704SS**Hα-helixtrans-77.8-19.9-178.8-71.4178.4-23.100114L770L770-Q772 VanDerWaalsContact C-N 3.25Å; L770-Q772 PolarHBondContact O-N 3.26Å
773G37Very low35.5Very low30 Ų30126.8 Ų126.831%0.30968%0.681SS.*Hα-helixtrans-70.8-41.7-174.800000114.5L770 N775 F776L770-G773 PolarHBondContact O-N 3.14Å; G773-N775 PolarHBondContact O-N 3.35Å; G773-F776 PolarHBondContact O-N 3.26Å
774K34.6Very low35.6Very low164 Ų164121 Ų12171%0.71367%0.667SS**Hα-helixtrans-66.5-39-172.9-79.3-174.2171.8-1790113.5
775N33.5Very low35.4Very low130 Ų130121.2 Ų121.270%0.69566%0.66SS**Hα-helixtrans-76.5-24.3-178.8-69.2-0.5000112.9G773 S779G773-N775 PolarHBondContact O-N 3.35Å; N775-S779 PolarHBondContact O-OG 3.26Å; N775-S779 VanDerWaalsContact O-OG 3.04Å
776F37Very low35.5Very low140 Ų140119.8 Ų119.861%0.61465%0.653SS**Hα-helixtrans-74.4-30.2179.5-163.7-103000113.3G773G773-F776 PolarHBondContact O-N 3.26Å
777L37.7Very low35.6Very low105 Ų105120 Ų12055%0.5565%0.647SS.*Hα-helixtrans-81-47.2177.3-92.6162.6000113S779 K780 F781L777-S779 PolarHBondContact O-N 3.24Å; L777-K780 PolarHBondContact O-N 3.48Å; L777-F781 HydrophobicContact CD2-CD2 4.15Å; L777-F781 HydrophobicContact CD2-CE2 3.82Å; L777-F781 PolarHBondContact O-N 3.31Å
778M34.4Very low35.3Very low141 Ų141114.3 Ų114.370%0.69563%0.626SS**Hα-helixtrans-70.8-30.1-171.5-78.8-65174.900114.8S782M778-S782 PolarHBondContact O-N 3.16Å; M778-S782 PolarHBondContact O-OG 3.1Å; M778-S782 VanDerWaalsContact O-OG 3.13Å
779S35Very low34.9Very low71 Ų71121.1 Ų121.150%0.49764%0.639SS.*Hα-helixtrans-68.2-33.9175.954.20000112.9N775 L777 S783N775-S779 PolarHBondContact O-OG 3.26Å; N775-S779 VanDerWaalsContact O-OG 3.04Å; L777-S779 PolarHBondContact O-N 3.24Å; S779-S783 PolarHBondContact O-N 3.36Å; S779-S783 PolarHBondContact O-OG 3.44Å
780K33Very low34.6Very low120 Ų120123.4 Ų123.452%0.52264%0.635SS.*Hα-helixtrans-82.8-34.1-178.9-74.8-178.8175.5172.20113.8L777 S783 L784L777-K780 PolarHBondContact O-N 3.48Å; K780-S783 PolarHBondContact O-OG 3.42Å; K780-L784 VanDerWaalsContact O-CB 3.29Å; K780-L784 WeakPolarHBondContact O-CB 3.47Å; K780-L784 PolarHBondContact O-N 2.75Å; K780-L784 VanDerWaalsContact O-N 3.1Å
781F32.8Very low34.3Very low129 Ų129121.6 Ų121.657%0.56663%0.63SS**Hα-helixtrans-67.9-39.5175.1-92-84.9000112.9L777 N785L777-F781 HydrophobicContact CD2-CD2 4.15Å; L777-F781 HydrophobicContact CD2-CE2 3.82Å; L777-F781 PolarHBondContact O-N 3.31Å; F781-N785 PolarHBondContact O-N 3.37Å
782S35Very low34Very low83 Ų83126 Ų12658%0.5863%0.632SS**Hα-helixtrans-64.7-47.2176.6-60.50000112.5M778 Q786M778-S782 PolarHBondContact O-N 3.16Å; M778-S782 PolarHBondContact O-OG 3.1Å; M778-S782 VanDerWaalsContact O-OG 3.13Å; S782-Q786 PolarHBondContact O-N 2.88Å
783S34.1Very low33.3Very low63 Ų63123.4 Ų123.444%0.44163%0.634SS.*Hα-helixtrans-72.1-28.7-17852.50000113.9S779 K780 K787S779-S783 PolarHBondContact O-N 3.36Å; S779-S783 PolarHBondContact O-OG 3.44Å; K780-S783 PolarHBondContact O-OG 3.42Å; S783-K787 PolarHBondContact O-N 3.41Å
784L33Very low32.9Very low111 Ų111129.2 Ų129.258%0.58166%0.658SS**Hα-helixtrans-71.9-44.2176.3-170.162000112.1K780 Q786 K787 V788K780-L784 VanDerWaalsContact O-CB 3.29Å; K780-L784 WeakPolarHBondContact O-CB 3.47Å; K780-L784 PolarHBondContact O-N 2.75Å; K780-L784 VanDerWaalsContact O-N 3.1Å; L784-Q786 VanDerWaalsContact C-N 3.26Å; L784-Q786 PolarHBondContact O-N 3.02Å; L784-K787 PolarHBondContact O-N 2.83Å; L784-V788 HydrophobicContact CD1-CG2 4.47Å; L784-V788 HydrophobicContact CG-CG2 4.43Å; L784-V788 WeakPolarHBondContact O-CG2 3.31Å; L784-V788 PolarHBondContact O-N 2.8Å
785N33.6Very low32.6Very low109 Ų109127.1 Ų127.158%0.58366%0.659SS**Hα-helixtrans-61.8-33.4178.1-97.5-42.8000112.8F781 K789F781-N785 PolarHBondContact O-N 3.37Å; N785-K789 PolarHBondContact O-N 2.81Å
786Q34.9Very low32Very low152 Ų152128.5 Ų128.571%0.7167%0.666SS**Hα-helixtrans-68.5-39.2176.3-135.8176.116.200112.5S782 L784S782-Q786 PolarHBondContact O-N 2.88Å; L784-Q786 VanDerWaalsContact C-N 3.26Å; L784-Q786 PolarHBondContact O-N 3.02Å
787K33.3Very low31.6Very low164 Ų164129.3 Ų129.371%0.71368%0.675SS**Hα-helixtrans-74.4-33175.7-83.7177.9175.2170.70113.6S783 L784 Q790S783-K787 PolarHBondContact O-N 3.41Å; L784-K787 PolarHBondContact O-N 2.83Å; K787-Q790 PolarHBondContact O-N 2.82Å
788V32.8Very low30.9Very low86 Ų86127 Ų12752%0.52168%0.677SS.*Hα-helixtrans-68.9-34177.31730000112L784 Q790 T791L784-V788 HydrophobicContact CD1-CG2 4.47Å; L784-V788 HydrophobicContact CG-CG2 4.43Å; L784-V788 WeakPolarHBondContact O-CG2 3.31Å; L784-V788 PolarHBondContact O-N 2.8Å; V788-Q790 PolarHBondContact O-N 2.94Å; V788-T791 PolarHBondContact O-N 2.76Å
789K30.7Very low30.5Very low200 Ų200128.1 Ų128.187%0.8769%0.686SS**THydrogen-bonded Turntrans-63.7-17.1174.7-89.3-176.7175.7175.40114.9N785N785-K789 PolarHBondContact O-N 2.81Å
790Q33.3Very low30Very low178 Ų178132.9 Ų132.983%0.83271%0.705SS**THydrogen-bonded Turntrans-97.70.7-179.5-67.5-165.1-2.100115.1K787 V788K787-Q790 PolarHBondContact O-N 2.82Å; V788-Q790 PolarHBondContact O-N 2.94Å
791T30.7Very low29.7Very low102 Ų102138.8 Ų138.863%0.62672%0.724SS**SBendtrans-131.7119.5-174.5-35.90000113V788V788-T791 PolarHBondContact O-N 2.76Å
792K28.7Very low29.4Very low185 Ų185142.4 Ų142.480%0.80474%0.739SS**  trans69.770.4177.8-57.3175.9-177.21730116.9
793S24.7Very low29Very low128 Ų128146.4 Ų146.490%0.89575%0.753SS**  trans-91.481.1140.146.50000109.1
794N28.2Very low28.5Very low152 Ų152146 Ų14681%0.81376%0.758SS**  trans-137.1133.9173.2-139.6-4.5000111.2
795V27.8Very low28.1Very low121 Ų121148.9 Ų148.973%0.73378%0.775SS**  trans-63.5136.6-165.9-177.20000111.7I797V795-I797 HydrophobicContact CG1-CG1 3.91Å
796N21.8Very low27.7Very low159 Ų159152.7 Ų152.785%0.8579%0.786SS**  trans-99.2106.7164.8-161.312.7000109.6
797I27.5Very low27.2Very low156 Ų156151.6 Ų151.680%0.879%0.79SS**  trans-89.6120.1173.2-74.7169.4000107.8V795V795-I797 HydrophobicContact CG1-CG1 3.91Å
798G23.5Very low26.8Very low57 Ų57153.2 Ų153.259%0.58880%0.797SS**  trans-155.960.7-168.500000115.8
799N26.1Very low26.4Very low164 Ų164154.4 Ų154.488%0.87781%0.807SS**  trans150109.6134.7-78.2-20.1000113.1
800L25.2Very low26.1Very low171 Ų171153.8 Ų153.890%0.89581%0.807SS**  trans-14880161.1-127.1170.8000109.9
801R26.3Very low25.6Very low245 Ų245153.5 Ų153.593%0.92581%0.808SS**  trans-150.272.5173.2-79.5-162.5175.8-163.9-0.3111.9
802K25.9Very low25.2Very low205 Ų205158.1 Ų158.189%0.89182%0.819SS**  trans-173.379.1150.8-111.2179.9-180-173.40112.9
803L26.6Very low25Very low167 Ų167155.5 Ų155.587%0.87482%0.819SS**  trans-169.8144.6149-12366.2000103.3
804G23.6Very low25Very low53 Ų53156.3 Ų156.355%0.54681%0.813SS.*  cis138.112014.300000105.5F806G804-F806 PolarHBondContact O-N 2.77Å; G804-F806 VanDerWaalsContact O-N 3.17Å
805N24.7Very low24.7Very low172 Ų172158.4 Ų158.492%0.9282%0.815SS**  trans-61.4120.8-171.7-81.5-3.3000111.1
806F24.9Very low24.5Very low189 Ų189161.1 Ų161.183%0.82983%0.825SS**  trans-129.5136.6163-84.9-81000110.2G804G804-F806 PolarHBondContact O-N 2.77Å; G804-F806 VanDerWaalsContact O-N 3.17Å
807T24.8Very low24.7Very low130 Ų130162.1 Ų162.180%0.79882%0.821SS**PPolyproline II helixtrans-72.6166.1177.4420000111.4P809T807-P809 WeakPolarHBondContact O-CD 3.4Å
808K24.1Very low24.8Very low197 Ų197160 Ų16086%0.85782%0.818SS**PPolyproline II helixtrans-51.4126.5172-69.3178.9175.5-178.90110.7
809P25.9Very low24.8Very low112 Ų112165 Ų16573%0.72783%0.831SS**PPolyproline II helixtrans-82.1122.415331.9-27.8000108.9T807T807-P809 WeakPolarHBondContact O-CD 3.4Å
810E24Very low24.7Very low186 Ų186165.4 Ų165.487%0.86983%0.832SS**PPolyproline II helixtrans-74.5134151.6-66-172.1144.100107.8
811M22.9Very low24.6Very low173 Ų173166.4 Ų166.485%0.85283%0.829SS**  trans-132.9113.1166.1-86.7-169.1162.700110.3
812K23Very low24.5Very low198 Ų198161.5 Ų161.586%0.86183%0.827SS**  trans-67.4131.6162.7-63177.3179.8178.40108
813V23.4Very low24.4Very low131 Ų131158.5 Ų158.579%0.79482%0.82SS**  trans-94.9111171.3-178.20000108
814N24Very low24.2Very low145 Ų145157.6 Ų157.678%0.77582%0.816SS**  trans-81.9139.4170-76-7.8000109.7
815F22.6Very low24.3Very low195 Ų195166.6 Ų166.686%0.85583%0.833SS**  trans-72.5137.2179.2-72-96000112.3
816L24.6Very low24.3Very low179 Ų179166.7 Ų166.794%0.93783%0.826SS**  trans-134126.3154.6-71.6175.5000108.1
817K25Very low24.3Very low179 Ų179163.4 Ų163.478%0.77883%0.826SS**  trans-90.3162-179.9-97.4-172.2177.2-179.80111.5
818P30.2Very low24.2Very low113 Ų113164.8 Ų164.873%0.73483%0.829SS**  trans-97.6170.7-152.938.2-38.4000115.2
819N22.3Very low24.2Very low161 Ų161161.2 Ų161.286%0.86183%0.828SS**  trans-148.5109.8159.4-98.9-66.6000110.8
820L25.5Very low24.1Very low172 Ų172161.5 Ų161.590%0.90183%0.833SS**  trans-159148.2146.9-138.782.3000109.8
821K23.2Very low24.1Very low192 Ų192160.3 Ų160.384%0.83583%0.832SS**  trans-95.4145.5-178.8-64.2177.4179178.70110.9
822V24Very low24.2Very low143 Ų143161.1 Ų161.187%0.86783%0.833SS**  trans-114.9127.9167.5179.70000107.8
823N24.1Very low24.3Very low142 Ų142157.2 Ų157.276%0.75983%0.826SS**  trans-90137.1176.2-80.2-12.7000110.7
824L22.3Very low24.3Very low148 Ų148160 Ų16078%0.77583%0.833SS**  trans-92.8130-179.1-175.877.8000110.2
825W25.3Very low24.3Very low242 Ų242161 Ų16192%0.91783%0.833SS**  trans-122.1137.4163-86.862.4000109.4
826K24.8Very low24.4Very low174 Ų174158.7 Ų158.776%0.75783%0.829SS**  trans-91.1160.2-173-65.9-178.5177-177.30111.5
827S24.1Very low24.3Very low120 Ų120156.3 Ų156.384%0.83982%0.822SS**  trans-107.6120.2164.4-510000108.4
828D22.1Very low24.3Very low159 Ų159151 Ų15185%0.8582%0.819SS**  trans-102.2159.1164.7-80.6-54.4000109.9
829S24Very low24Very low122 Ų122152 Ų15285%0.85382%0.823SS**  trans-139123.5-163.8168.40000112.1
830S24.7Very low24.1Very low117 Ų117152 Ų15282%0.81882%0.82SS**  trans-158.8149157.249.90000110.8
831L24.4Very low24Very low162 Ų162149.1 Ų149.185%0.84881%0.805SS**  trans-149.9106.1176.8-167.8171.1000105.7
832E25Very low24.1Very low189 Ų189147.8 Ų147.888%0.88380%0.799SS**  trans-100.6147.1179.3-72.4-165.8152.800111.9
833T24.1Very low24Very low117 Ų117147.2 Ų147.272%0.71880%0.796SS**  trans-95.5151-176.947.50000111.8
834M24.3Very low24Very low190 Ų190149.2 Ų149.294%0.93680%0.8SS**  trans-128.3125.4149.7-73.2-154.874.500110.2
835E23.2Very low24.1Very low165 Ų165146.1 Ų146.177%0.77180%0.796SS**  trans-102.4159.7171.7-58.5-177.3122.800110.2
836N24.4Very low24.1Very low146 Ų146143.4 Ų143.478%0.78179%0.794SS**  trans157.4141.5150-85.1-17.1000109.7
837T24.1Very low24.1Very low129 Ų129139.9 Ų139.979%0.79179%0.79SS**  cis-164.5140.7-12.4100000109.8
838G23.1Very low24.2Very low68 Ų68141.9 Ų141.970%0.70179%0.792SS**  trans84.7116132.200000123
839V25.3Very low24.3Very low134 Ų134137.3 Ų137.381%0.81278%0.782SS**  trans79.3115.2134.9-173.40000120.9
840M23.7Very low24.4Very low162 Ų162138.4 Ų138.480%0.79878%0.779SS**  trans37.1151139.7-56.8172.463.100121.5
841D23.7Very low24.5Very low110 Ų110140 Ų14059%0.58878%0.775SS**  cis-154.1173.825.5-155.11.3000113.8
842K24.4Very low24.6Very low164 Ų164136.9 Ų136.971%0.71377%0.767SS**  trans8125.5167.4-74.5153.8-168.6150.30125
843V23.6Very low24.7Very low132 Ų132132.1 Ų132.180%0.875%0.754SS**  43.5114115.6-173.60000121.4
844Q23.2Very low24.8Very low184 Ų184134.3 Ų134.386%0.8676%0.762SS**  -164.5137.6124.7-102.3168.7-54.600107.7
845A24.8Very low25Very low82 Ų82132.1 Ų132.168%0.67875%0.754SS**  58.613183.600000111.8
846E25Very low25.1Very low186 Ų186131.3 Ų131.387%0.86976%0.755SS**  cis-152.5174.415.9-63.5-177.4154.500108.1
847S25.2Very low25.3Very low99 Ų99127.7 Ų127.769%0.69274%0.741SS**  cis-162.4-175.6-6.435.90000110.1
848D26Very low25.4Very low163 Ų163132.3 Ų132.387%0.87275%0.745SS**  trans-11158.2155.9-47-31.9000120.4
849G24.9Very low25.6Very low63 Ų63135.7 Ų135.765%0.64974%0.743SS**  cis155.4169.80.800000111.9
850D26.3Very low25.8Very low145 Ų145135.2 Ų135.278%0.77575%0.745SS**  trans62.5158.5160.8-78.89000119.3
851M25Very low25.9Very low150 Ų150134 Ų13474%0.73974%0.742SS**  cis-151.7-174.4-4.4-122-64.1163.800112
852S27.3Very low26.1Very low96 Ų96136.6 Ų136.667%0.67175%0.751SS**  trans-48.3162.5165.761.20000114.3
853S28.1Very low26.1Very low89 Ų89137.8 Ų137.862%0.62276%0.756SS**  -179.3152.564.3178.50000111.8
854D25.3Very low26.2Very low164 Ų164138.8 Ų138.888%0.87776%0.756SS**  -177.3158.6110.7-92.4-7.4000114.8
855N28.6Very low26.4Very low144 Ų144136.9 Ų136.977%0.7776%0.757SS**  trans-134.2152.5-159.7179.233000109.5
856D25.5Very low26.4Very low147 Ų147139.9 Ų139.979%0.78676%0.762SS**  trans-159.4158.1148.8-134.2-25.3000113.7
857S28.2Very low26.5Very low71 Ų71136.4 Ų136.450%0.49776%0.758SS.*  trans-119.1177-159.469.30000114.4
858Y25.5Very low26.7Very low225 Ų225139.8 Ų139.888%0.88276%0.76SS**  trans-167.7160.8130.1-105.2-69.8000110.9
859H28.8Very low26.7Very low139 Ų139137.7 Ų137.764%0.64476%0.758SS**  trans-93.2157.8-154.4-75.7-116.3000117.4D861H859-D861 IonicContact ND1-OD1 2.71Å
860S28.3Very low26.9Very low124 Ų124140.4 Ų140.487%0.86776%0.758SS**  trans-154.3136.7137.4-64.10000107.9
861D25.9Very low26.9Very low136 Ų136143.2 Ų143.273%0.72777%0.767SS**  trans-92155.3-166-47.6-82.2000114H859H859-D861 IonicContact ND1-OD1 2.71Å
862E28.2Very low27Very low166 Ų166141.9 Ų141.978%0.77676%0.763SS**  -171.4139.4114.3-106.7-170.8171.100114.5
863F25.6Very low26.9Very low188 Ų188147.2 Ų147.283%0.82577%0.768SS**  trans56.9138.5163.3-73-79.1000123.3
864L25.3Very low26.7Very low154 Ų154151.6 Ų151.681%0.80678%0.779SS**  trans-106.6149.8-175.6-64.2159.8000111.5
865T26.3Very low26.8Very low143 Ų143151.6 Ų151.688%0.87778%0.778SS**  -152.8140.1127.136.80000110.9
866N25.5Very low26.6Very low145 Ų145149 Ų14978%0.77578%0.776SS**  trans-72.5176.3166.4-60.5-38.7000109.8
867S27.1Very low26.6Very low113 Ų113149.7 Ų149.779%0.7978%0.78SS**  cis-153.3161.719.3-42.70000112.1
868K29.3Very low26.4Very low170 Ų170151.7 Ų151.774%0.73979%0.794SS**  trans-69.4159.4155.7-75.2179.6147.2-136.70111.4D870K868-D870 WeakPolarHBondContact CD-OD2 3.47Å; K868-D870 IonicContact NZ-OD1 3.53Å; K868-D870 IonicContact NZ-OD2 3.99Å; K868-D870 PolarHBondContact NZ-OD2 2.98Å
869S26.9Very low26.5Very low119 Ų119148.2 Ų148.283%0.83279%0.79SS**  trans-144103.3139.657.50000108.8
870D27.3Very low26.4Very low120 Ų120149.8 Ų149.864%0.64280%0.797SS**  trans-81.5139.4162.8-54.7-73.7000107.7K868K868-D870 WeakPolarHBondContact CD-OD2 3.47Å; K868-D870 IonicContact NZ-OD1 3.53Å; K868-D870 IonicContact NZ-OD2 3.99Å; K868-D870 PolarHBondContact NZ-OD2 2.98Å
871E26.4Very low26.4Very low204 Ų204149.4 Ų149.495%0.95380%0.795SS**  trans-127.7149.7156.8-82.4-151.3144.300109.5
872D27Very low26.4Very low123 Ų123149.1 Ų149.166%0.65880%0.798SS**  trans-120.9145.2-146.4-160.419000113.1
873R26.4Very low26.4Very low207 Ų207143.8 Ų143.878%0.78179%0.788SS**  trans33.1130.7162.2-66138.192.5179.57.9120.4
874Q24.4Very low26.6Very low181 Ų181141.2 Ų141.285%0.84679%0.79SS**  -152.1154.7119.4-122.9163.782.500114.4
875L26.3Very low26.6Very low165 Ų165138.5 Ų138.586%0.86478%0.779SS**  trans62.1105.8167-60.1170.6000117.9
876A25.4Very low26.7Very low89 Ų89138.6 Ų138.674%0.73678%0.775SS**  trans-99.1139.9157.800000110.2
877N24.5Very low27Very low162 Ų162140.7 Ų140.787%0.86677%0.773SS**  trans-175.4147.5141.6-99.2-28.1000113
878S25.1Very low27.4Very low113 Ų113141.1 Ų141.179%0.7977%0.771SS**  trans78.3150.816776.90000120.5
879L27Very low27.9Very low152 Ų152135.5 Ų135.580%0.79675%0.748SS**  trans71.484.2171.8-97.463.1000120.8
880E26.6Very low28.6Very low171 Ų171136.2 Ų136.280%0.79975%0.75SS**  20.7126.1122-61.3178129.300121.2
881S28.7Very low29.7Very low116 Ų116132.8 Ų132.881%0.81174%0.736SS**  trans24.5110.7148.862.80000120.6
882V25.2Very low31Very low130 Ų130123.4 Ų123.479%0.78869%0.692SS**  trans-125.5134.4145.7-177.70000108V885V882-V885 HydrophobicContact CG1-CG2 4.19Å
883G28.2Very low32.8Very low55 Ų55119.4 Ų119.457%0.56768%0.68SS**  trans-74.5-175.7177.900000113.4V885G883-V885 PolarHBondContact O-N 2.96Å; G883-V885 VanDerWaalsContact O-N 3.15Å
884P29Very low34.9Very low133 Ų133113 Ų11386%0.86466%0.66SS**  trans-60.1120.1174.226.2-33.7000110.3D886P884-D886 PolarHBondContact O-N 2.52Å
885V25.5Very low37.2Very low97 Ų97107.3 Ų107.359%0.58864%0.635SS**  trans-77.9106178.8176.60000109.4V882 G883 Y887V882-V885 HydrophobicContact CG1-CG2 4.19Å; G883-V885 PolarHBondContact O-N 2.96Å; G883-V885 VanDerWaalsContact O-N 3.15Å; V885-Y887 HydrophobicContact CG1-CD2 4.34Å; V885-Y887 HydrophobicContact CG1-CE2 4.28Å; V885-Y887 WeakPolarHBondContact O-CD2 3.33Å; V885-Y887 PolarHBondContact O-N 2.93Å
886D28.1Very low38.8Very low146 Ų146103.1 Ų103.178%0.78162%0.624SS**  trans-65.2111.5166.8-86.9-40.4000109.8P884 V888P884-D886 PolarHBondContact O-N 2.52Å; D886-V888 HydrophobicContact CB-CG2 4.35Å; D886-V888 PolarHBondContact O-N 2.92Å
887Y32.8Very low39.8Very low189 Ų189100.8 Ų100.874%0.74160%0.602SS**  trans-74.768.9174.9-84.9-96.3000111.5V885 L889V885-Y887 HydrophobicContact CG1-CD2 4.34Å; V885-Y887 HydrophobicContact CG1-CE2 4.28Å; V885-Y887 WeakPolarHBondContact O-CD2 3.33Å; V885-Y887 PolarHBondContact O-N 2.93Å; Y887-L889 PolarHBondContact O-N 2.85Å
888V36.3Very low40.3Very low122 Ų12296.8 Ų96.874%0.73959%0.592SS**  trans-75.189.9167.4-175.40000108.5D886 P890D886-V888 HydrophobicContact CB-CG2 4.35Å; D886-V888 PolarHBondContact O-N 2.92Å; V888-P890 VanDerWaalsContact O-CD 3.31Å; V888-P890 WeakPolarHBondContact O-CD 3.33Å
889L39.5Very low40.6Very low51 Ų5195.9 Ų95.927%0.26758%0.584SS.*  trans-64.8120.6172.5-69.8175.9000109.5L396 Y887 S891 C892L396-L889 HydrophobicContact CD2-CD1 3.75Å; Y887-L889 PolarHBondContact O-N 2.85Å; L889-S891 PolarHBondContact O-N 3.13Å; L889-C892 PolarHBondContact O-N 3.4Å; L889-C892 VanDerWaalsContact O-N 3.17Å
890P41.3Very low40.7Very low135 Ų135100.7 Ų100.788%0.87759%0.591SS**THydrogen-bonded Turntrans-62-11.2180-24.335.1000114.4V888V888-P890 VanDerWaalsContact O-CD 3.31Å; V888-P890 WeakPolarHBondContact O-CD 3.33Å
891S48.9Very low40.8Very low48 Ų48101 Ų10134%0.33660%0.597SS.*THydrogen-bonded Turntrans-100.4-5.7-177.1-3.30000114.3N399 N400 S401 L889N399-S891 WeakPolarHBondContact ND2-CB 3.44Å; N399-S891 PolarHBondContact ND2-OG 3.43Å; N399-S891 VanDerWaalsContact OD1-CB 3.31Å; N399-S891 WeakPolarHBondContact OD1-CB 3.46Å; N399-S891 PolarHBondContact OD1-OG 3.06Å; N400-S891 CarbonylContact C-O 3.6Å; S401-S891 WeakPolarHBondContact CA-O 3.44Å; S401-S891 PolarHBondContact N-O 2.86Å; S401-S891 VanDerWaalsContact N-O 3.07Å; L889-S891 PolarHBondContact O-N 3.13Å
892C54.5Low40.8Very low7 Ų799.1 Ų99.15%0.04760%0.596CS.*SBendtrans-140.6112.9178.9-116.50000111.2N400 L889 I894N400-C892 PolarHBondContact N-SG 2.96Å; N400-C892 VanDerWaalsContact N-SG 3.39Å; N400-C892 PolarHBondContact O-SG 3.15Å; N400-C892 VanDerWaalsContact O-SG 3.41Å; L889-C892 PolarHBondContact O-N 3.4Å; L889-C892 VanDerWaalsContact O-N 3.17Å; C892-I894 PolarHBondContact O-N 2.94Å
893G65Low40.9Very low38 Ų3898.7 Ų98.739%0.39260%0.599SS.*EExtended strand (participates in β ladder)trans-69.4110.9178.200000111.6T404 Y405T404-G893 CarbonylContact C-O 3.6Å; T404-G893 WeakPolarHBondContact CA-O 3.41Å; T404-G893 WeakPolarHBondContact CG2-O 3.35Å; Y405-G893 PolarHBondContact N-O 3.19Å
894I70.9Confident40.8Very low73 Ų73107 Ų10737%0.37461%0.613SS.*EExtended strand (participates in β ladder)trans-109.3124.4174.6-63.2173000108.7L392 L396 Y405 C892L392-I894 HydrophobicContact CD1-CD1 4.26Å; L396-I894 HydrophobicContact CD2-CD1 3.57Å; L396-I894 HydrophobicContact CG-CD1 4.34Å; Y405-I894 WeakPolarHBondContact O-CA 3.34Å; C892-I894 PolarHBondContact O-N 2.94Å
895I72.9Confident40.7Very low62 Ų62106.6 Ų106.632%0.31861%0.614SS.*EExtended strand (participates in β ladder)trans-122.1115.2178.7-55.9177.7000108.3T404 Y405 V406 S407 I432T404-I895 HydrophobicContact CG2-CD1 4.46Å; Y405-I895 PolarHBondContact O-N 3.47Å; V406-I895 WeakPolarHBondContact CA-O 3.5Å; V406-I895 HydrophobicContact CG1-CB 4.4Å; V406-I895 HydrophobicContact CG1-CG2 4.46Å; V406-I895 HydrophobicContact CG2-CB 4.31Å; V406-I895 HydrophobicContact CG2-CD1 4.43Å; S407-I895 PolarHBondContact N-O 2.92Å; I432-I895 HydrophobicContact CD1-CD1 3.68Å
896A59Low40.8Very low77 Ų77109.5 Ų109.564%0.63662%0.621SS**EExtended strand (participates in β ladder)trans-101.9123.4172.300000109.7A898A896-A898 VanDerWaalsContact C-N 3.3Å; A896-A898 PolarHBondContact O-N 2.87Å
897S47.1Very low40.7Very low39 Ų39108.1 Ų108.127%0.27362%0.623SS.*  trans-7778.8174.766.50000111S407 F408S407-S897 PolarHBondContact O-N 3.16Å; S407-S897 PolarHBondContact O-OG 3.14Å; F408-S897 WeakPolarHBondContact CD2-OG 3.48Å
898A35.1Very low40.3Very low78 Ų78107.1 Ų107.165%0.64563%0.629SS**  trans-70.5137.7170.300000110.5A896 R900A896-A898 VanDerWaalsContact C-N 3.3Å; A896-A898 PolarHBondContact O-N 2.87Å; A898-R900 PolarHBondContact O-N 3.41Å
899P31.5Very low39.6Very low95 Ų95106.2 Ų106.262%0.61763%0.628SS**  trans-68.6115.2179.927.2-33.7000110.7L901P899-L901 PolarHBondContact O-N 2.76Å; P899-L901 VanDerWaalsContact O-N 3.14Å
900R29.4Very low39.1Very low252 Ų252109 Ų10995%0.95165%0.652SS**  trans-67.3111.3173-70.3-171.5179.5-171.91.3109.7A898 G902A898-R900 PolarHBondContact O-N 3.41Å; R900-G902 PolarHBondContact O-N 3.39Å; R900-G902 VanDerWaalsContact O-N 3.12Å
901L28.4Very low38.3Very low178 Ų178109.3 Ų109.393%0.93265%0.652SS**  trans-65.7107.8173.3-90.4160.2000110.8P899P899-L901 PolarHBondContact O-N 2.76Å; P899-L901 VanDerWaalsContact O-N 3.14Å
902G29.1Very low37.2Very low77 Ų77114.1 Ų114.179%0.79467%0.673SS**  trans52.995.3152.300000118.4R900R900-G902 PolarHBondContact O-N 3.39Å; R900-G902 VanDerWaalsContact O-N 3.12Å
903S25.5Very low35.8Very low121 Ų121118.9 Ų118.985%0.84671%0.707SS**  trans-129124.2146.4-1700000109.5S905S903-S905 PolarHBondContact O-N 2.58Å
904R28Very low33.9Very low229 Ų229122 Ų12286%0.86472%0.723SS**  trans-88.6101.6-179.8-85.9-179.7165.6177.5-3.9109.8Q906R904-Q906 PolarHBondContact O-N 2.87Å
905S26.7Very low31.7Very low124 Ų124126 Ų12687%0.86774%0.743SS**  trans-77.291.8161.338.60000110S903S903-S905 PolarHBondContact O-N 2.58Å
906Q27.5Very low29.4Very low159 Ų159132 Ų13274%0.74377%0.769SS**  trans-83119.8164.8-78.5-173.2-36.400109.8R904R904-Q906 PolarHBondContact O-N 2.87Å
907S25.4Very low27.8Very low117 Ų117131.9 Ų131.982%0.81877%0.769SS**  trans-78.3124.7169.553.60000110.5
908L24.3Very low27Very low168 Ų168135.8 Ų135.888%0.8879%0.793SS**  trans-126.9142.5165.8-76.6174.7000110.1
909S22.8Very low26.6Very low103 Ų103136.4 Ų136.472%0.7279%0.793SS**  trans-99.1127.3-172.952.60000112.5
910S27.5Very low26.4Very low108 Ų108139.4 Ų139.476%0.75580%0.799SS**  trans26.6117.6145.960.30000120.4
911T25.7Very low26.3Very low143 Ų143133.3 Ų133.388%0.87778%0.784SS**  trans-151.7154.3133.924.40000110
912D26.1Very low26.1Very low148 Ų148130.8 Ų130.879%0.79178%0.776SS**  trans-76.6152.5-172.2-50-93000114.8
913S23.8Very low26.1Very low107 Ų107132.6 Ų132.675%0.74877%0.771SS**  171146.1113.5-75.80000115.5
914S24.3Very low26.2Very low105 Ų105131.1 Ų131.173%0.73477%0.766SS**  trans45.498.714961.40000121.5
915I26.5Very low26.4Very low156 Ų156129.1 Ų129.180%0.877%0.766SS**  21.4121.2121.3-57167.3000117.5
916H23.8Very low26.5Very low187 Ų187126.9 Ų126.987%0.86676%0.763SS**  -157.9134.2123.3-119-77.7000112.7
917A25.3Very low26.6Very low76 Ų76125.3 Ų125.363%0.62877%0.77SS**  trans-97.3161.116500000109.8
918P29.6Very low26.8Very low120 Ų120122.5 Ų122.578%0.77976%0.759SS**  -142.4144.999.636.7-22.7000116.3
919S27.8Very low27.2Very low92 Ų92123.3 Ų123.364%0.64376%0.763SS**  24146.6113.1-52.80000120.3
920E27.5Very low27.6Very low157 Ų157121.7 Ų121.773%0.73476%0.763SS**  cis-173.1169.34.2-120174.5138.700113.3
921I26.8Very low27.7Very low125 Ų125127.2 Ų127.264%0.64177%0.773SS**  trans64.9127.5147.9-68.7161.4000117.3
922T25Very low27.9Very low125 Ų125123.4 Ų123.477%0.76776%0.763SS**  -163.411862.5-36.60000108.3
923V27.4Very low28.1Very low114 Ų114124.6 Ų124.669%0.69176%0.763SS**  70.911371.3177.80000116
924A27.9Very low28.3Very low90 Ų90127.2 Ų127.274%0.74476%0.764SS**  trans-168.7117.8138.800000113.8
925H31.9Very low28.4Very low187 Ų187127.1 Ų127.187%0.86676%0.763SS**  trans4.9149154.6-54.8-77.9000122.1
926G28.8Very low29.6Very low77 Ų77124.3 Ų124.379%0.79476%0.755SS**  cis163.7-174.66.800000109.1
927S30.3Very low30Very low127 Ų127122.2 Ų122.289%0.88875%0.75SS**  cis-165.6178.4-10.3680000107.3
928G29.5Very low30.2Very low57 Ų57126.9 Ų126.959%0.58876%0.756SS**  cis174.1178.73.600000113
929L32.5Very low30.1Very low186 Ų186130.7 Ų130.797%0.97476%0.76SS**  trans66.1138.7177.3-66.286.2000118.3
930G30.6Very low30.2Very low69 Ų69131.7 Ų131.771%0.71177%0.767SS**  cis164.4156.5-14.100000116.6
931K31.4Very low31.2Very low223 Ų223129.5 Ų129.597%0.9777%0.767SS**  trans70.2145169.2-53.3-179.2179.2-177.70118.1
932G29.2Very low31.3Very low64 Ų64128.6 Ų128.666%0.6677%0.771SS**  cis156.9145-15.100000115.7
933Q30.8Very low31.5Very low172 Ų172127.9 Ų127.980%0.80478%0.778SS**  trans66.2155.2159.3-70.3169.5-77.100117.9
934E26.6Very low31.5Very low162 Ų162125.8 Ų125.876%0.75778%0.78SS**  cis-152.8-156.1-6.8-133.1156.5-143.400113.6
935S27Very low31.5Very low104 Ų104129.5 Ų129.573%0.72779%0.787SS**  trans-144.8-146.2-172.455.70000110.2
936P51.3Low31.5Very low97 Ų97128 Ų12863%0.6378%0.784SS**  cis-144.7176.7-6.545.9-27.7000118.6
937L31.8Very low31.4Very low143 Ų143133 Ų13375%0.74979%0.786SS**  trans67.2158.9149.5-68.4158.8000120.4
938K31.3Very low31.3Very low174 Ų174134.5 Ų134.576%0.75778%0.782SS**  cis-173.9159.7-23.3-168.2-179.1-115.11680111.7
939K27.7Very low31.2Very low199 Ų199139.1 Ų139.187%0.86579%0.793SS**  trans113161.2154.1-63.9-172.8177.9-179.70118.7
940S30Very low31Very low114 Ų114137.1 Ų137.180%0.79779%0.788SS**  trans-141.6-174-165.365.30000109.2
941P47.1Very low30.8Very low111 Ų111136.5 Ų136.572%0.72178%0.782SS**  cis-150.1-168.930.945.3-22.7000119.4
942S28.9Very low30.6Very low106 Ų106136.1 Ų136.174%0.74178%0.781SS**  trans78.1106.4149.962.40000123.8
943A30.2Very low30.7Very low110 Ų110137.3 Ų137.391%0.90979%0.785SS**  trans67.3117.3131.200000122.1
944G26.2Very low31.1Very low70 Ų70137.1 Ų137.172%0.72278%0.781SS**  trans170.9104.2160.900000115.2
945N29.5Very low31.7Very low168 Ų168135 Ų13590%0.89878%0.781SS**  trans57.9150.7164.7-64.1-17.5000120.1
946I32Very low32Very low155 Ų155136.9 Ų136.980%0.79578%0.781SS**  trans-98.2109.2-174.4-61.3171.8000110.3
947H26.2Very low31.4Very low181 Ų181136.9 Ų136.984%0.83878%0.775SS**  trans-135.1118.9156.4-94-87.8000107.4
948I28.1Very low31.7Very low159 Ų159136.2 Ų136.282%0.81577%0.771SS**PPolyproline II helixtrans-92.1134.9178.9-65.8179.9000109.4
949L26.5Very low32.1Very low154 Ų154137.1 Ų137.181%0.80677%0.771SS**PPolyproline II helixtrans-66.7137.9-175.3-87.864.8000112.7
950T28.2Very low32.6Very low144 Ų144131.6 Ų131.688%0.88376%0.756SS**PPolyproline II helixtrans-60.7132146.543.20000109.6
951G26.9Very low33.1Very low57 Ų57133.1 Ų133.159%0.58875%0.751SS**  trans-154.5145.4-179.800000114.9
952F28.3Very low32.6Very low214 Ų214136.1 Ų136.194%0.93975%0.748SS**  trans71122160.1-58.3-77.2000119.4
953A31.3Very low33.1Very low89 Ų89138.6 Ų138.674%0.73675%0.745SS**  trans-68.5161.7169.800000111.9
954K38.8Very low33.8Very low169 Ų169137 Ų13774%0.73572%0.724SS**  trans-89.2157.6-170.8-66.7178.7179.1177.40112.3M956K954-M956 PolarHBondContact O-N 3.33Å
955P37.6Very low34.3Very low116 Ų116139.3 Ų139.375%0.75372%0.716SS**THydrogen-bonded Turntrans-67.55.9-173-23.135.5000117.9
956M34.4Very low34.7Very low145 Ų145136.5 Ų136.571%0.71470%0.701SS**Hα-helixtrans-76.5-36.2-175.4-75.4-177.6167.900113.6K954 I958 Y959 C960K954-M956 PolarHBondContact O-N 3.33Å; M956-I958 VanDerWaalsContact C-N 3.27Å; M956-I958 PolarHBondContact O-N 2.93Å; M956-Y959 PolarHBondContact O-N 2.99Å; M956-Y959 VanDerWaalsContact O-N 3.11Å; M956-C960 PolarHBondContact O-N 3.48Å; M956-C960 PolarHBondContact O-SG 2.85Å; M956-C960 VanDerWaalsContact O-SG 3.42Å
957D38.7Very low35.1Very low96 Ų96132.5 Ų132.551%0.51369%0.691SS.*Hα-helixtrans-65.9-32.3-171.4-55.1-40.2000112.3Y959 H961D957-Y959 VanDerWaalsContact C-N 3.34Å; D957-Y959 PolarHBondContact O-N 2.85Å; D957-H961 PolarHBondContact O-N 3.21Å
958I38.4Very low35.6Very low129 Ų129130.3 Ų130.366%0.66268%0.681SS**Hα-helixtrans-68.2-32.7177.9-60.5176.2000111.4M956 R962M956-I958 VanDerWaalsContact C-N 3.27Å; M956-I958 PolarHBondContact O-N 2.93Å; I958-R962 PolarHBondContact O-N 3.25Å
959Y38.1Very low35.8Very low193 Ų193128.8 Ų128.876%0.75768%0.675SS**Hα-helixtrans-78.6-40.5-179.7-143.4-82.9000111.5M956 D957 R962 F963M956-Y959 PolarHBondContact O-N 2.99Å; M956-Y959 VanDerWaalsContact O-N 3.11Å; D957-Y959 VanDerWaalsContact C-N 3.34Å; D957-Y959 PolarHBondContact O-N 2.85Å; Y959-R962 PolarHBondContact O-N 2.91Å; Y959-F963 PolarHBondContact O-N 3.37Å
960C38.9Very low36.3Very low83 Ų83130.8 Ų130.856%0.56168%0.677SS**Hα-helixtrans-64-43.7178.8-61.40000111.9M956 R962 V964M956-C960 PolarHBondContact O-N 3.48Å; M956-C960 PolarHBondContact O-SG 2.85Å; M956-C960 VanDerWaalsContact O-SG 3.42Å; C960-R962 VanDerWaalsContact C-N 3.33Å; C960-R962 PolarHBondContact O-N 3.29Å; C960-V964 PolarHBondContact O-N 3.17Å
961H39.9Very low36.5Very low147 Ų147129.7 Ų129.768%0.68167%0.67SS**Hα-helixtrans-61.2-39.1175.9-95.3-73.4000113D957 V964 Q965D957-H961 PolarHBondContact O-N 3.21Å; H961-V964 PolarHBondContact O-N 2.98Å; H961-Q965 WeakPolarHBondContact O-CB 3.27Å; H961-Q965 PolarHBondContact O-N 3.31Å; H961-Q965 VanDerWaalsContact O-N 3.14Å
962R37.5Very low36.5Very low173 Ų173133 Ų13365%0.65368%0.679SS**Hα-helixtrans-69.4-40.2-176.5-152.8168.5-167.7154.52.9112.4I958 Y959 C960 V964 Q965 D966I958-R962 PolarHBondContact O-N 3.25Å; Y959-R962 PolarHBondContact O-N 2.91Å; C960-R962 VanDerWaalsContact C-N 3.33Å; C960-R962 PolarHBondContact O-N 3.29Å; R962-V964 PolarHBondContact O-N 2.86Å; R962-Q965 PolarHBondContact O-N 2.9Å; R962-D966 PolarHBondContact O-N 2.94Å
963F38.9Very low36.4Very low158 Ų158131.2 Ų131.269%0.69367%0.673SS**Hα-helixtrans-63.9-39.6177-171.2-101.3000112.7Y959 Q965 A967Y959-F963 PolarHBondContact O-N 3.37Å; F963-Q965 VanDerWaalsContact C-N 3.33Å; F963-A967 WeakPolarHBondContact O-CB 3.31Å; F963-A967 PolarHBondContact O-N 2.89Å
964V44.2Very low36.2Very low77 Ų77134.3 Ų134.347%0.46768%0.676SS.*Hα-helixtrans-65.9-37.4174.8174.90000111.5C960 H961 R962 A967 Q968C960-V964 PolarHBondContact O-N 3.17Å; H961-V964 PolarHBondContact O-N 2.98Å; R962-V964 PolarHBondContact O-N 2.86Å; V964-A967 PolarHBondContact O-N 2.98Å; V964-Q968 WeakPolarHBondContact O-CG 3.44Å; V964-Q968 PolarHBondContact O-N 3.39Å
965Q37.7Very low35.6Very low119 Ų119131.3 Ų131.356%0.55668%0.677SS**Hα-helixtrans-71.4-39.9-178.1-156.4166.227.200112.5H961 R962 F963 A967 Q968 N969H961-Q965 WeakPolarHBondContact O-CB 3.27Å; H961-Q965 PolarHBondContact O-N 3.31Å; H961-Q965 VanDerWaalsContact O-N 3.14Å; R962-Q965 PolarHBondContact O-N 2.9Å; F963-Q965 VanDerWaalsContact C-N 3.33Å; Q965-A967 VanDerWaalsContact C-N 3.35Å; Q965-Q968 PolarHBondContact O-N 3.34Å; Q965-N969 PolarHBondContact O-N 3Å; Q965-N969 PolarHBondContact O-ND2 3.38Å
966D38Very low35.1Very low109 Ų109133.4 Ų133.458%0.58368%0.677SS**Hα-helixtrans-68.7-32.3174.4-74.2-22.4000112.4R962 Q968R962-D966 PolarHBondContact O-N 2.94Å; D966-Q968 VanDerWaalsContact C-N 3.31Å; D966-Q968 PolarHBondContact O-N 3.26Å
967A39.8Very low35.2Very low71 Ų71131.7 Ų131.759%0.58768%0.676SS**Hα-helixtrans-67.1-29.3174.400000113.3F963 V964 Q965F963-A967 WeakPolarHBondContact O-CB 3.31Å; F963-A967 PolarHBondContact O-N 2.89Å; V964-A967 PolarHBondContact O-N 2.98Å; Q965-A967 VanDerWaalsContact C-N 3.35Å
968Q36.6Very low34.5Very low135 Ų135137.4 Ų137.463%0.63169%0.691SS**Hα-helixtrans-81.5-29.5179.4-72.3173.5-10.300112.9V964 Q965 D966 K970V964-Q968 WeakPolarHBondContact O-CG 3.44Å; V964-Q968 PolarHBondContact O-N 3.39Å; Q965-Q968 PolarHBondContact O-N 3.34Å; D966-Q968 VanDerWaalsContact C-N 3.31Å; D966-Q968 PolarHBondContact O-N 3.26Å; Q968-K970 PolarHBondContact O-N 3.06Å
969N34Very low33.8Very low126 Ų126136.1 Ų136.167%0.67469%0.693SS**THydrogen-bonded Turntrans-76.412.5-174.1-79.4-32000115.9Q965Q965-N969 PolarHBondContact O-N 3Å; Q965-N969 PolarHBondContact O-ND2 3.38Å
970K35.1Very low33Very low197 Ų197133 Ų13386%0.85769%0.694SS**THydrogen-bonded Turntrans-116.512.2176.9-115.4-179.3-177.6179.60115.9Q968Q968-K970 PolarHBondContact O-N 3.06Å
971V32.6Very low32.4Very low121 Ų121134.1 Ų134.173%0.73370%0.702SS**  trans-133.5107.3170.8-177.60000110.2
972T26.9Very low31.8Very low126 Ų126135.4 Ų135.477%0.77371%0.709SS**  trans159.2110.2139.1-69.60000112.1
973H26Very low31.2Very low177 Ų177136.1 Ų136.182%0.81972%0.72SS**  trans173.5136.7160.1-91.2-75.3000105.7
974L28Very low30.5Very low153 Ų153132.5 Ų132.580%0.80172%0.719SS**  cis-155.6154.9-15.9-81.5174000105.9
975S25.5Very low29.6Very low107 Ų107133.4 Ų133.475%0.74873%0.728SS**  cis-159.2-179.7-12.662.20000110.2
976E28.4Very low29.1Very low160 Ų160135.2 Ų135.275%0.74874%0.737SS**  trans-67.3170.6160.6-100-170.7-159.500112.6
977P35.7Very low28.5Very low109 Ų109136.4 Ų136.471%0.70874%0.739SS**  cis-150.516335.343.1-22000121.9
978R23.3Very low27.8Very low215 Ų215143.1 Ų143.181%0.81175%0.749SS**  trans55.898.1137.7-69.8-178.7-178.8-173.4-0.7124.4
979S23.6Very low27.4Very low102 Ų102144.1 Ų144.171%0.71376%0.759SS**  71.2133.2104.479.10000125.8
980V23.1Very low27Very low128 Ų128147.5 Ų147.578%0.77677%0.771SS**  trans85.8107.6150.8-164.60000122
981S24.6Very low26.5Very low106 Ų106145.7 Ų145.774%0.74177%0.767SS**  -175.4127.1124.118.10000109.1
982Q27.4Very low26.2Very low175 Ų175144.9 Ų144.982%0.81876%0.763SS**  46.7114.590.1-62.7-170.6-8.500112.6
983Q25.7Very low26.2Very low188 Ų188149 Ų14988%0.87976%0.764SS**  -165.7165.858-81176.9-15.100109.6
984A25.3Very low26.1Very low82 Ų82147 Ų14768%0.67876%0.755SS**  cis-163.8-178.6-14.100000110.5
985S25.2Very low26Very low95 Ų95145.6 Ų145.666%0.66475%0.753SS**  trans2.7146.215254.30000120.7
986Q26.8Very low25.9Very low158 Ų158145 Ų14574%0.73875%0.748SS**  cis-165.1169.99.1-123.8167.6-68.600112.9
987E25.7Very low25.8Very low133 Ų133143.8 Ų143.862%0.62175%0.747SS**  trans7.6155141.7-70.2-177.2111.700122.5
988R25.1Very low25.3Very low212 Ų212146.7 Ų146.780%0.875%0.751SS**  cis-174.4157.1-12.4180172.9-168.1163.8-0.3109.8
989N28.1Very low25.4Very low156 Ų156144.2 Ų144.283%0.83475%0.749SS**  trans-60.9141.6-177.3-55.4-12.3000115.8
990Q25Very low25.3Very low198 Ų198144.2 Ų144.293%0.92575%0.745SS**  trans-168.1166.1143.9-109169.41900110.5
991M25.4Very low25.4Very low158 Ų158147 Ų14778%0.77875%0.749SS**  -179138.8-74.7171.5164.5170.600110.2
992T25.3Very low25.3Very low105 Ų105147.2 Ų147.264%0.64475%0.75SS**  trans70.7142.8163.840.10000123.1
993R26.2Very low25.3Very low211 Ų211147.6 Ų147.680%0.79675%0.752SS**  trans73.3152.4154.9-72.2158.7174.6-113.96.5116.9
994E25.2Very low25.3Very low135 Ų135143.6 Ų143.663%0.63175%0.745SS**  cis-150.3133.13.9-127.5140.4-135.300108.2
995V25.3Very low25.7Very low125 Ų125145.7 Ų145.776%0.75875%0.75SS**  93.6128.795.31600000117.4
996S24Very low25.8Very low93 Ų93150.7 Ų150.765%0.6576%0.763SS**  trans42123.6158.169.50000123.9
997N26Very low26Very low136 Ų136151.1 Ų151.173%0.72777%0.765SS**  -179.5143.5109.4-84.74.5000108.2
998E25Very low26.5Very low170 Ų170151.1 Ų151.179%0.79477%0.774SS**  55.1129.868.1-77.4-176.4-16700113.7
999E25.1Very low27.5Very low162 Ų162146.2 Ų146.276%0.75777%0.769SS**  cis-165-172.5-15.2-143.3-170.2-161.100109.4
1000T23Very low27.7Very low102 Ų102144.1 Ų144.163%0.62677%0.767SS**  trans64.6123.3159.338.30000122.9
1001Q23.8Very low27.8Very low188 Ų188146.4 Ų146.488%0.87977%0.767SS**  trans68.7152133.9-71.1175.116.900120
1002S23.5Very low29.1Very low109 Ų109143.8 Ų143.876%0.76276%0.762SS**  cis-148.9175.3-2.161.40000113
1003E25.9Very low29.5Very low183 Ų183144 Ų14486%0.85577%0.768SS**  trans-68174.5155.3-45.1168.4108.500109.8
1004S27.7Very low29.6Very low104 Ų104143 Ų14373%0.72777%0.773SS**  cis-160.4157.27.956.70000112
1005T33.3Very low29.7Very low127 Ų127143.7 Ų143.778%0.77978%0.78SS**  trans18.5130.1144.5-43.50000122.3
1006E25.6Very low29.6Very low200 Ų200144.8 Ų144.894%0.93578%0.781SS**  trans-153.9175.5151.4-138174.3-149.100113.6
1007Q32.6Very low29.7Very low167 Ų167146.1 Ų146.178%0.7879%0.785SS**  trans-132.3115.7-165.2-74.4-172.1-16.700117.6
1008T34.8Very low29.8Very low133 Ų133144.3 Ų144.382%0.81678%0.783SS**  trans64.5176.7144.874.10000119.1
1009P47.7Very low29.9Very low108 Ų108143 Ų14370%0.70178%0.781SS**  cis-136.9159.4-9.839-21000119.1
1010S30.5Very low30.2Very low113 Ų113140.7 Ų140.779%0.7978%0.782SS**  trans67.9136.3141.971.30000126.1
1011R28.5Very low30.4Very low245 Ų245139.7 Ų139.793%0.92579%0.785SS**  trans-174.6169.5138.4-101.8-145.3141.5169.4-6.1114
1012P53.3Low30.5Very low103 Ų103137.7 Ų137.767%0.66979%0.785SS**  trans-143.5-162.7-140.147.6-29.2000119.7
1013S33Very low30.5Very low111 Ų111135.8 Ų135.878%0.77678%0.783SS**  trans88.8154.3164.278.20000118.2
1014Q28.1Very low31.7Very low190 Ų190132.9 Ų132.989%0.88878%0.78SS**  cis-126.5-142.512.4-62.3177.6-80.500115.1
1015L26.2Very low31.6Very low149 Ų149136.7 Ų136.778%0.7879%0.786SS**  -161.4142.7-129-161.4177.7000113.3
1016D23.3Very low31.2Very low147 Ų147139.8 Ų139.879%0.78679%0.79SS**  trans-170.1140.3141.3-108.3-25.6000118.2
1017V27.6Very low31.1Very low122 Ų122137.3 Ų137.374%0.73978%0.782SS**  trans7.7141.9148.5171.70000119.9
1018S26.7Very low30.6Very low97 Ų97134 Ų13468%0.67878%0.777SS**  cis-169.3-149.7-9.854.60000109.3
1019L28.1Very low30Very low143 Ų143134.5 Ų134.575%0.74978%0.779SS**  cis-167.21275.8-136.6176.4000113.3
1020S30.2Very low28.9Very low113 Ų113137.7 Ų137.779%0.7979%0.785SS**  trans60.6151.4156.275.80000122.1
1021A27.9Very low29.2Very low82 Ų82137.8 Ų137.868%0.67878%0.783SS**  cis-152.71467.700000116.2
1022T26.1Very low28.9Very low145 Ų145129.5 Ų129.589%0.8977%0.767SS**  trans56.7133.6144.2510000125.8
1023G23Very low27.5Very low69 Ų69133.2 Ų133.271%0.71178%0.775SS**  trans-127.6-142.3149.200000108.8
1024P51.6Low27.1Very low122 Ų122132.4 Ų132.479%0.79277%0.769SS**  cis-136.8-167.8-2042.2-23.5000113.6
1025Q25.5Very low26.9Very low184 Ų184130.1 Ų130.186%0.8677%0.768SS**  trans157.2-166.3141-82.5-167.1-700115.9
1026F25.4Very low26.8Very low193 Ų193126.8 Ų126.885%0.84676%0.762SS**  trans-129.6162.6-143.4-90.9-93000117.3
1027L22.6Very low26.8Very low148 Ų148124.4 Ų124.478%0.77576%0.757SS**  trans76.7114.5144.4-80.8164.6000124.1
1028S23Very low26.7Very low97 Ų97125.2 Ų125.268%0.67875%0.752SS**  trans46.7139.3131.8660000124.2
1029V22.5Very low26.5Very low143 Ų143128.5 Ų128.587%0.86775%0.754SS**  170.1145.6124.4149.40000113
1030E23.9Very low26.2Very low176 Ų176127.6 Ų127.682%0.82276%0.755SS**  trans-85.5-177.9171-82.6-164.1134.400111.8
1031P35.8Very low26.5Very low115 Ų115128 Ų12875%0.74776%0.755SS**  cis-148.8-165.418.341.3-17.2000118
1032A23.3Very low26.2Very low70 Ų70129 Ų12958%0.57976%0.757SS**  trans90.2116.3134.300000124.1
1033H24.6Very low26.1Very low182 Ų182127.7 Ų127.784%0.84375%0.754SS**  trans65.9159.7132.3-60.5-36.9000121.4
1034S23.9Very low26.1Very low94 Ų94128.7 Ų128.766%0.65776%0.755SS**  cis-174.4179-31.1620000110.4
1035V23.8Very low24.8Very low141 Ų141128.3 Ų128.386%0.85576%0.755SS**  trans74.9147.2165.5177.10000117.6
1036A23.6Very low24.7Very low80 Ų80125.3 Ų125.366%0.66176%0.755SS**  cis-175.7174.6-35.900000110.4
1037S23.6Very low24.5Very low96 Ų96123.5 Ų123.567%0.67175%0.751SS**  trans74.3145142.2174.80000119.7
1038Q24.8Very low24.6Very low139 Ų139123.6 Ų123.665%0.6575%0.752SS**  cis-165.5154.8-8.7-107.2171.767.700112.8
1039K22.8Very low24.6Very low166 Ų166125.9 Ų125.972%0.72275%0.752SS**  trans60.8117.7141-68.8172.1-179.21590124.7
1040T23.3Very low24.7Very low124 Ų124125.8 Ų125.876%0.76175%0.745SS**  11.4154110.657.90000120.4
1041P35.2Very low24.6Very low123 Ų123124.8 Ų124.880%0.79974%0.741SS**  cis-140.4-148.93544-22.4000113.4
1042S22.7Very low24Very low102 Ų102125.2 Ų125.271%0.71374%0.741SS**  cis-157.4141.62.847.40000115.6
1043S24Very low24Very low117 Ų117125.5 Ų125.582%0.81875%0.751SS**  trans-20.2142.7155.755.40000124.8
1044A23.2Very low24.1Very low90 Ų90123.8 Ų123.874%0.74475%0.747SS**  trans177.9119.5143.200000109.9
1045S23Very low24.2Very low114 Ų114127.7 Ų127.780%0.79776%0.755SS**  60.3137.984.470.70000115.9
1046S22.8Very low24.2Very low121 Ų121127.3 Ų127.385%0.84675%0.752SS**  cis-158.1-17213.851.80000114.2
1047M22.7Very low24.1Very low156 Ų156129.5 Ų129.577%0.76876%0.757SS**  trans-82.9171.8-173.5-63.9166.351.900117.1
1048L23.3Very low25Very low150 Ų150129.8 Ų129.879%0.78576%0.757SS**  trans140.7159.5140.6-75.2165.6000111.6
1049E23.8Very low24.9Very low145 Ų145128.2 Ų128.268%0.67876%0.761SS**  cis-172.1146.9-45.6-129.4-179.8-164.700109.7
1050L24Very low25.9Very low140 Ų140125.7 Ų125.773%0.73376%0.762SS**  trans59.2169.5157.5-101.558.9000119.7
1051E23.1Very low25.9Very low156 Ų156125.8 Ų125.873%0.72977%0.768SS**  cis-152.6179.92.7-147.8160.6-154.200113.9
1052T23.2Very low25.5Very low124 Ų124128.8 Ų128.876%0.76177%0.771SS**  trans-20.5165.6172.850.20000122.7
1053G23.6Very low25.6Very low75 Ų75129 Ų12977%0.77377%0.773SS**  cis174.5-153.112.400000111.1
1054L26.1Very low25.7Very low147 Ų147129.4 Ų129.477%0.7778%0.775SS**  cis-172.8115.8-9.2-162.4148.4000113.5
1055H25.4Very low25.9Very low176 Ų176131.2 Ų131.282%0.81578%0.783SS**  trans63.2167.5167.4-69.4-116.5000119.5
1056V24.2Very low26.2Very low133 Ų133131.4 Ų131.481%0.80678%0.784SS**  cis-146.4170.729.4176.20000112.4
1057T21.6Very low26.6Very low125 Ų125137.7 Ų137.777%0.76779%0.789SS**  trans-142.8-169-177.963.80000111.1
1058P41.5Very low27Very low102 Ų102134.7 Ų134.766%0.66279%0.789SS**  cis-144.7-174-0.644.4-24.4000118.6
1059S24.2Very low27.4Very low106 Ų106133.5 Ų133.574%0.74179%0.788SS**  trans74.4165145.576.60000122.2
1060P42.1Very low27.9Very low113 Ų113127.9 Ų127.973%0.73477%0.765SS**  cis-140165.1-45.137.8-21.7000115.9
1061S24.7Very low28.4Very low127 Ų127123.8 Ų123.889%0.88875%0.746SS**  trans178.5166.8140.734.40000115.1
1062E26Very low29.3Very low186 Ų186117.2 Ų117.287%0.86972%0.715SS**  trans-79.5-173.6-167.5-58.2172.916700116.1
1063S26Very low30.1Very low107 Ų107113.8 Ų113.875%0.74870%0.699SS**  -170148.4-5774.80000109.9
1064S24.6Very low30.7Very low124 Ų124117.3 Ų117.387%0.86769%0.693SS**  trans-170.7140.514956.80000110.4
1065S28.8Very low31.4Very low129 Ų129114.3 Ų114.390%0.90268%0.677SS**  trans-141.7157.7-176.165.10000112.3
1066S27.7Very low32Very low117 Ų117110.2 Ų110.282%0.81866%0.655SS**  trans-123.6137.5176.258.10000110.5A1068S1066-A1068 PolarHBondContact O-N 3.41Å
1067R31.3Very low32.7Very low254 Ų254106.9 Ų106.996%0.95864%0.637SS**  trans-74.3116.7-163.2-122.3174.3178.2165.1-1.4112.5
1068A32Very low33.5Very low93 Ų93104 Ų10477%0.76962%0.622SS**  trans-82.6163.8161.100000110.8S1066S1066-A1068 PolarHBondContact O-N 3.41Å
1069V31.9Very low33.4Very low125 Ų125103.1 Ų103.176%0.75861%0.61SS**  trans-98115.8177.5178.60000109.9A1073V1069-A1073 HydrophobicContact CG1-CB 4.1Å
1070S34.3Very low34.2Very low27 Ų27102.6 Ų102.619%0.18960%0.602CS.*  trans-55.2141.9-178.8171.30000113.2D656 F1072 A1073D656-S1070 VanDerWaalsContact OD1-CB 3.25Å; D656-S1070 WeakPolarHBondContact OD1-CB 3.32Å; D656-S1070 PolarHBondContact OD1-OG 3.01Å; S1070-F1072 PolarHBondContact O-N 3.09Å; S1070-F1072 PolarHBondContact OG-N 2.92Å; S1070-A1073 WeakPolarHBondContact O-CB 3.4Å; S1070-A1073 PolarHBondContact O-N 2.84Å
1071P35.3Very low33.9Very low53 Ų53102.4 Ų102.434%0.34459%0.591SS.*THydrogen-bonded Turntrans-55.8-26.9172.7-27.538.5000114.2D659 A1073 K1074 I1075D659-P1071 VanDerWaalsContact OD1-CD 3.3Å; D659-P1071 WeakPolarHBondContact OD1-CD 3.25Å; D659-P1071 VanDerWaalsContact OD1-CG 3.31Å; D659-P1071 WeakPolarHBondContact OD1-CG 3.24Å; P1071-A1073 PolarHBondContact O-N 3.2Å; P1071-K1074 WeakPolarHBondContact O-CB 3.27Å; P1071-K1074 PolarHBondContact O-N 3.11Å; P1071-I1075 PolarHBondContact O-N 3.04Å
1072F40.4Very low34.5Very low19 Ų1999.4 Ų99.48%0.08357%0.568CS.*Hα-helixtrans-57.3-32.7177.2-101.2-116.4000112.7D639 Y654 S1070 K1074 I1075 R1076D639-F1072 WeakPolarHBondContact OD2-CD1 3.43Å; Y654-F1072 AromaticContact CD1-CD2 3.84Å; Y654-F1072 HydrophobicContact CD1-CD2 3.84Å; Y654-F1072 AromaticContact CD1-CE2 3.55Å; Y654-F1072 HydrophobicContact CD1-CE2 3.55Å; Y654-F1072 HydrophobicContact CD1-CZ 4.05Å; Y654-F1072 AromaticContact CD2-CE2 3.67Å; Y654-F1072 HydrophobicContact CD2-CE2 3.67Å; Y654-F1072 AromaticContact CD2-CZ 3.83Å; Y654-F1072 HydrophobicContact CD2-CZ 3.83Å; Y654-F1072 AromaticContact CE1-CD2 3.59Å; Y654-F1072 HydrophobicContact CE1-CD2 3.59Å; Y654-F1072 AromaticContact CE1-CE2 3.44Å; Y654-F1072 HydrophobicContact CE1-CE2 3.44Å; Y654-F1072 VanDerWaalsContact CE1-CE2 3.44Å; Y654-F1072 HydrophobicContact CE1-CZ 4.36Å; Y654-F1072 AromaticContact CE2-CE2 3.59Å; Y654-F1072 HydrophobicContact CE2-CE2 3.59Å; Y654-F1072 HydrophobicContact CE2-CZ 4.19Å; Y654-F1072 HydrophobicContact CG-CD2 4.38Å; Y654-F1072 AromaticContact CG-CE2 3.65Å; Y654-F1072 HydrophobicContact CG-CE2 3.65Å; Y654-F1072 AromaticContact CG-CZ 3.76Å; Y654-F1072 HydrophobicContact CG-CZ 3.76Å; Y654-F1072 AromaticContact CZ-CD2 3.96Å; Y654-F1072 AromaticContact CZ-CE2 3.45Å; Y654-F1072 VanDerWaalsContact CZ-CE2 3.45Å; S1070-F1072 PolarHBondContact O-N 3.09Å; S1070-F1072 PolarHBondContact OG-N 2.92Å; F1072-K1074 PolarHBondContact O-N 2.84Å; F1072-K1074 VanDerWaalsContact O-N 3.17Å; F1072-I1075 HydrophobicContact CD2-CD1 4.32Å; F1072-I1075 HydrophobicContact CE2-CD1 4.38Å; F1072-I1075 PolarHBondContact O-N 2.73Å; F1072-R1076 WeakPolarHBondContact O-CB 3.22Å; F1072-R1076 PolarHBondContact O-N 2.85Å
1073A40.4Very low35Very low51 Ų5193.6 Ų93.642%0.42155%0.551SS.*Hα-helixtrans-59.4-28.5174.400000113.2V1069 S1070 P1071 S1077V1069-A1073 HydrophobicContact CG1-CB 4.1Å; S1070-A1073 WeakPolarHBondContact O-CB 3.4Å; S1070-A1073 PolarHBondContact O-N 2.84Å; P1071-A1073 PolarHBondContact O-N 3.2Å; A1073-S1077 WeakPolarHBondContact O-CB 3.35Å; A1073-S1077 PolarHBondContact O-N 2.93Å
1074K37Very low35.4Very low150 Ų15091.1 Ų91.165%0.65253%0.534SS*.Hα-helixtrans-82.4-40.9176.8-62.8173.3-176.2166.50111.8P1071 F1072 S1077 S1078P1071-K1074 WeakPolarHBondContact O-CB 3.27Å; P1071-K1074 PolarHBondContact O-N 3.11Å; F1072-K1074 PolarHBondContact O-N 2.84Å; F1072-K1074 VanDerWaalsContact O-N 3.17Å; K1074-S1077 WeakPolarHBondContact O-CB 3.2Å; K1074-S1077 PolarHBondContact O-N 2.93Å; K1074-S1078 PolarHBondContact O-N 3.43Å; K1074-S1078 PolarHBondContact O-OG 3.44Å; K1074-S1078 VanDerWaalsContact O-OG 3.13Å
1075I39.8Very low36Very low84 Ų8489.8 Ų89.843%0.43152%0.516SS..Hα-helixtrans-61.9-47.5174.7-59.8173.6000109.8P1071 F1072 S1077 S1078 M1079P1071-I1075 PolarHBondContact O-N 3.04Å; F1072-I1075 HydrophobicContact CD2-CD1 4.32Å; F1072-I1075 HydrophobicContact CE2-CD1 4.38Å; F1072-I1075 PolarHBondContact O-N 2.73Å; I1075-S1077 VanDerWaalsContact C-N 3.28Å; I1075-S1077 PolarHBondContact O-N 2.85Å; I1075-S1078 PolarHBondContact O-N 2.78Å; I1075-M1079 HydrophobicContact CG2-SD 4.29Å; I1075-M1079 PolarHBondContact O-N 2.93Å
1076R39.4Very low36.5Very low90 Ų9088.1 Ų88.134%0.3450%0.501SS..Hα-helixtrans-58.5-35.6175.4-159.6-178.8-67.7-179.7-3.2112D639 F1072 V1080D639-R1076 IonicContact OD1-CZ 2.74Å; D639-R1076 IonicContact OD1-NH2 2.76Å; D639-R1076 PolarHBondContact OD1-NH2 2.91Å; D639-R1076 IonicContact OD2-CZ 2.71Å; D639-R1076 IonicContact OD2-NH2 3.65Å; D639-R1076 PolarHBondContact OD2-NH2 2.95Å; F1072-R1076 WeakPolarHBondContact O-CB 3.22Å; F1072-R1076 PolarHBondContact O-N 2.85Å; R1076-V1080 VanDerWaalsContact O-CG2 3.28Å; R1076-V1080 WeakPolarHBondContact O-CG2 3.42Å; R1076-V1080 PolarHBondContact O-N 2.91Å
1077S37.9Very low37Very low62 Ų6289.1 Ų89.143%0.43449%0.493SS..Hα-helixtrans-69-45.4171.1-1720000112.5A1073 K1074 I1075 V1080 Q1081A1073-S1077 WeakPolarHBondContact O-CB 3.35Å; A1073-S1077 PolarHBondContact O-N 2.93Å; K1074-S1077 WeakPolarHBondContact O-CB 3.2Å; K1074-S1077 PolarHBondContact O-N 2.93Å; I1075-S1077 VanDerWaalsContact C-N 3.28Å; I1075-S1077 PolarHBondContact O-N 2.85Å; S1077-V1080 PolarHBondContact O-N 2.68Å; S1077-Q1081 WeakPolarHBondContact O-CG 3.4Å; S1077-Q1081 PolarHBondContact O-N 3.5Å
1078S39.2Very low37.4Very low65 Ų6579.7 Ų79.746%0.45547%0.469SS..Hα-helixtrans-64.6-43.3-177.3-64.60000112.8K1074 I1075 Q1081 V1082K1074-S1078 PolarHBondContact O-N 3.43Å; K1074-S1078 PolarHBondContact O-OG 3.44Å; K1074-S1078 VanDerWaalsContact O-OG 3.13Å; I1075-S1078 PolarHBondContact O-N 2.78Å; S1078-Q1081 PolarHBondContact O-N 3.12Å; S1078-V1082 WeakPolarHBondContact O-CG2 3.43Å; S1078-V1082 PolarHBondContact O-N 2.82Å
1079M39.1Very low37.7Very low83 Ų8377.3 Ų77.341%0.40945%0.454SS..Hα-helixtrans-68.1-37179.4-64.2-175.181.200112I1075 Q1081 V1082 A1083I1075-M1079 HydrophobicContact CG2-SD 4.29Å; I1075-M1079 PolarHBondContact O-N 2.93Å; M1079-Q1081 VanDerWaalsContact C-N 3.34Å; M1079-V1082 PolarHBondContact O-N 2.69Å; M1079-A1083 WeakPolarHBondContact O-CB 3.45Å; M1079-A1083 PolarHBondContact O-N 3.03Å
1080V40.3Very low38Very low95 Ų9577 Ų7758%0.57645%0.447SS*.Hα-helixtrans-66.3-35.5172.3171.80000111.7R1076 S1077 S1084R1076-V1080 VanDerWaalsContact O-CG2 3.28Å; R1076-V1080 WeakPolarHBondContact O-CG2 3.42Å; R1076-V1080 PolarHBondContact O-N 2.91Å; S1077-V1080 PolarHBondContact O-N 2.68Å; V1080-S1084 WeakPolarHBondContact O-CB 3.46Å; V1080-S1084 PolarHBondContact O-N 2.68Å; V1080-S1084 PolarHBondContact O-OG 3.27Å
1081Q34.9Very low38.2Very low109 Ų10979 Ų7951%0.50946%0.458SS..Hα-helixtrans-66.4-41.9171.2-75-175.7-8600112S1077 S1078 M1079 S1084 I1085S1077-Q1081 WeakPolarHBondContact O-CG 3.4Å; S1077-Q1081 PolarHBondContact O-N 3.5Å; S1078-Q1081 PolarHBondContact O-N 3.12Å; M1079-Q1081 VanDerWaalsContact C-N 3.34Å; Q1081-S1084 PolarHBondContact O-OG 2.81Å; Q1081-I1085 VanDerWaalsContact O-CB 3.24Å; Q1081-I1085 WeakPolarHBondContact O-CB 3.32Å; Q1081-I1085 WeakPolarHBondContact O-CD1 3.42Å; Q1081-I1085 WeakPolarHBondContact O-CG1 3.29Å; Q1081-I1085 PolarHBondContact O-N 3.44Å
1082V37.6Very low38.5Very low65 Ų6583.5 Ų83.539%0.39447%0.474SS..Hα-helixtrans-62.3-49175.7171.60000110.9L603 S1078 M1079 S1084 I1085 T1086L603-V1082 HydrophobicContact CD1-CG2 3.95Å; S1078-V1082 WeakPolarHBondContact O-CG2 3.43Å; S1078-V1082 PolarHBondContact O-N 2.82Å; M1079-V1082 PolarHBondContact O-N 2.69Å; V1082-S1084 PolarHBondContact O-N 2.71Å; V1082-I1085 PolarHBondContact O-N 2.8Å; V1082-T1086 PolarHBondContact O-N 2.83Å; V1082-T1086 PolarHBondContact O-OG1 2.92Å; V1082-T1086 VanDerWaalsContact O-OG1 3.07Å
1083A36.7Very low38.4Very low63 Ų6384.5 Ų84.552%0.52149%0.49SS..Hα-helixtrans-58.1-47.6178.400000112.2M1079 T1086 Q1087M1079-A1083 WeakPolarHBondContact O-CB 3.45Å; M1079-A1083 PolarHBondContact O-N 3.03Å; A1083-T1086 PolarHBondContact O-N 3.05Å; A1083-Q1087 WeakPolarHBondContact O-CB 3.28Å; A1083-Q1087 PolarHBondContact O-N 2.75Å
1084S35.1Very low38.4Very low56 Ų5685.9 Ų85.939%0.39249%0.49SS..Hα-helixtrans-70.4-29.4178.2560000113.5V1080 Q1081 V1082 A1088V1080-S1084 WeakPolarHBondContact O-CB 3.46Å; V1080-S1084 PolarHBondContact O-N 2.68Å; V1080-S1084 PolarHBondContact O-OG 3.27Å; Q1081-S1084 PolarHBondContact O-OG 2.81Å; V1082-S1084 PolarHBondContact O-N 2.71Å; S1084-A1088 WeakPolarHBondContact O-CB 3.31Å; S1084-A1088 PolarHBondContact O-N 2.83Å
1085I37.7Very low38.7Very low95 Ų9583.2 Ų83.249%0.48748%0.483SS..Hα-helixtrans-68.9-41.4171.3-73.7165.5000110.9Q1081 V1082 G1089Q1081-I1085 VanDerWaalsContact O-CB 3.24Å; Q1081-I1085 WeakPolarHBondContact O-CB 3.32Å; Q1081-I1085 WeakPolarHBondContact O-CD1 3.42Å; Q1081-I1085 WeakPolarHBondContact O-CG1 3.29Å; Q1081-I1085 PolarHBondContact O-N 3.44Å; V1082-I1085 PolarHBondContact O-N 2.8Å; I1085-G1089 WeakPolarHBondContact O-CA 3.25Å; I1085-G1089 PolarHBondContact O-N 2.94Å
1086T37.7Very low38.7Very low94 Ų9486 Ų8658%0.57749%0.492SS*.Hα-helixtrans-65.7-45.1175.6-56.10000111.1V1082 A1083 G1089 L1090V1082-T1086 PolarHBondContact O-N 2.83Å; V1082-T1086 PolarHBondContact O-OG1 2.92Å; V1082-T1086 VanDerWaalsContact O-OG1 3.07Å; A1083-T1086 PolarHBondContact O-N 3.05Å; T1086-G1089 PolarHBondContact O-N 2.75Å; T1086-L1090 WeakPolarHBondContact O-CB 3.31Å; T1086-L1090 PolarHBondContact O-N 3.33Å
1087Q38.2Very low38.7Very low139 Ų13984.2 Ų84.265%0.6550%0.496SS*.Hα-helixtrans-65.1-44.1177.1-167.9-177.625.200112.2A1083 T1091A1083-Q1087 WeakPolarHBondContact O-CB 3.28Å; A1083-Q1087 PolarHBondContact O-N 2.75Å; Q1087-T1091 WeakPolarHBondContact O-CB 3.34Å; Q1087-T1091 PolarHBondContact O-N 2.8Å; Q1087-T1091 PolarHBondContact O-OG1 3.25Å
1088A39.8Very low38.9Very low55 Ų5583.5 Ų83.546%0.45549%0.489SS..Hα-helixtrans-66.9-37.9175.200000111.9S1084 T1091 H1092S1084-A1088 WeakPolarHBondContact O-CB 3.31Å; S1084-A1088 PolarHBondContact O-N 2.83Å; A1088-T1091 PolarHBondContact O-N 2.82Å; A1088-H1092 WeakPolarHBondContact O-CB 3.44Å; A1088-H1092 PolarHBondContact O-N 3.22Å
1089G38Very low39.1Very low44 Ų4482.2 Ų82.245%0.45448%0.482SS..Hα-helixtrans-64.8-44.2175.900000112.5I1085 T1086 H1092 G1093I1085-G1089 WeakPolarHBondContact O-CA 3.25Å; I1085-G1089 PolarHBondContact O-N 2.94Å; T1086-G1089 PolarHBondContact O-N 2.75Å; G1089-H1092 PolarHBondContact O-N 3.47Å; G1089-G1093 PolarHBondContact O-N 3.19Å
1090L38.4Very low39.1Very low117 Ų11785 Ų8561%0.61349%0.492SS*.Hα-helixtrans-60.7-46172.1-172.169.7000110.8T1086 H1092 G1093 I1094T1086-L1090 WeakPolarHBondContact O-CB 3.31Å; T1086-L1090 PolarHBondContact O-N 3.33Å; L1090-H1092 VanDerWaalsContact C-N 3.35Å; L1090-H1092 PolarHBondContact O-N 3.26Å; L1090-G1093 PolarHBondContact O-N 2.95Å; L1090-I1094 HydrophobicContact CG-CD1 4.06Å; L1090-I1094 VanDerWaalsContact O-CG1 3.3Å; L1090-I1094 WeakPolarHBondContact O-CG1 3.33Å; L1090-I1094 PolarHBondContact O-N 2.8Å
1091T40Very low39.2Very low70 Ų7086.1 Ų86.143%0.42950%0.499SS..Hα-helixtrans-63.3-37.8177-55.60000112.1Q1087 A1088 N1095Q1087-T1091 WeakPolarHBondContact O-CB 3.34Å; Q1087-T1091 PolarHBondContact O-N 2.8Å; Q1087-T1091 PolarHBondContact O-OG1 3.25Å; A1088-T1091 PolarHBondContact O-N 2.82Å; T1091-N1095 WeakPolarHBondContact O-CB 3.38Å; T1091-N1095 PolarHBondContact O-N 3.43Å; T1091-N1095 PolarHBondContact O-ND2 3.24Å
1092H40.7Very low39.7Very low147 Ų14788.2 Ų88.268%0.68151%0.509SS*.Hα-helixtrans-70.6-38.9174.4-12376.1000111.8A1088 G1089 L1090 N1095 F1096A1088-H1092 WeakPolarHBondContact O-CB 3.44Å; A1088-H1092 PolarHBondContact O-N 3.22Å; G1089-H1092 PolarHBondContact O-N 3.47Å; L1090-H1092 VanDerWaalsContact C-N 3.35Å; L1090-H1092 PolarHBondContact O-N 3.26Å; H1092-N1095 PolarHBondContact O-N 3.01Å; H1092-F1096 WeakPolarHBondContact O-CB 3.41Å; H1092-F1096 PolarHBondContact O-N 3.17Å
1093G37.6Very low39.8Very low41 Ų4193.2 Ų93.242%0.42353%0.525SS..Hα-helixtrans-62.7-44.717500000112.2G1089 L1090 F1096 A1097G1089-G1093 PolarHBondContact O-N 3.19Å; L1090-G1093 PolarHBondContact O-N 2.95Å; G1093-F1096 PolarHBondContact O-N 3.03Å; G1093-A1097 WeakPolarHBondContact O-CB 3.41Å; G1093-A1097 PolarHBondContact O-N 3.46Å
1094I42Very low39.7Very low80 Ų8094.6 Ų94.641%0.4153%0.531SS..Hα-helixtrans-62-50.4174.2-68.8166.1000110.4L1090 F1096 A1097 V1098L1090-I1094 HydrophobicContact CG-CD1 4.06Å; L1090-I1094 VanDerWaalsContact O-CG1 3.3Å; L1090-I1094 WeakPolarHBondContact O-CG1 3.33Å; L1090-I1094 PolarHBondContact O-N 2.8Å; I1094-F1096 VanDerWaalsContact C-N 3.3Å; I1094-F1096 PolarHBondContact O-N 3.4Å; I1094-A1097 PolarHBondContact O-N 2.96Å; I1094-V1098 WeakPolarHBondContact O-CG2 3.28Å; I1094-V1098 PolarHBondContact O-N 2.82Å
1095N41.6Very low39.9Very low94 Ų9497.7 Ų97.750%0.50355%0.55SS..Hα-helixtrans-63.6-34.2178.2-77.5-49.5000112.9T1091 H1092 A1099T1091-N1095 WeakPolarHBondContact O-CB 3.38Å; T1091-N1095 PolarHBondContact O-N 3.43Å; T1091-N1095 PolarHBondContact O-ND2 3.24Å; H1092-N1095 PolarHBondContact O-N 3.01Å; N1095-A1099 WeakPolarHBondContact O-CB 3.15Å; N1095-A1099 PolarHBondContact O-N 2.81Å
1096F40.2Very low39.9Very low143 Ų14398 Ų9863%0.62757%0.567SS**Hα-helixtrans-70.5-40.1174.9-175.4-100000111.8H1092 G1093 I1094 A1099 K1100H1092-F1096 WeakPolarHBondContact O-CB 3.41Å; H1092-F1096 PolarHBondContact O-N 3.17Å; G1093-F1096 PolarHBondContact O-N 3.03Å; I1094-F1096 VanDerWaalsContact C-N 3.3Å; I1094-F1096 PolarHBondContact O-N 3.4Å; F1096-A1099 PolarHBondContact O-N 3.27Å; F1096-K1100 VanDerWaalsContact O-CB 3.29Å; F1096-K1100 WeakPolarHBondContact O-CB 3.38Å; F1096-K1100 PolarHBondContact O-N 3.33Å
1097A40.2Very low39.7Very low52 Ų52102.1 Ų102.143%0.4358%0.58SS.*Hα-helixtrans-62.9-47.6173.300000111.4G1093 I1094 A1099 K1100 V1101G1093-A1097 WeakPolarHBondContact O-CB 3.41Å; G1093-A1097 PolarHBondContact O-N 3.46Å; I1094-A1097 PolarHBondContact O-N 2.96Å; A1097-A1099 PolarHBondContact O-N 3.26Å; A1097-K1100 PolarHBondContact O-N 2.77Å; A1097-V1101 WeakPolarHBondContact O-CG2 3.33Å; A1097-V1101 PolarHBondContact O-N 2.97Å
1098V42.3Very low39.9Very low46 Ų46101.7 Ų101.728%0.27959%0.589SS.*Hα-helixtrans-57.6-48.9173.9169.80000110.8I1094 K1100 V1101 Q1102I1094-V1098 WeakPolarHBondContact O-CG2 3.28Å; I1094-V1098 PolarHBondContact O-N 2.82Å; V1098-K1100 VanDerWaalsContact C-N 3.27Å; V1098-K1100 PolarHBondContact O-N 2.99Å; V1098-V1101 PolarHBondContact O-N 3.31Å; V1098-Q1102 HydrophobicContact CG1-CG 4.43Å; V1098-Q1102 WeakPolarHBondContact O-CB 3.39Å; V1098-Q1102 VanDerWaalsContact O-CG 3.3Å; V1098-Q1102 WeakPolarHBondContact O-CG 3.49Å; V1098-Q1102 PolarHBondContact O-N 2.81Å
1099A43.5Very low39.8Very low38 Ų38107.4 Ų107.431%0.31461%0.606SS.*Hα-helixtrans-65.6-26.9178.800000113.6N1095 F1096 A1097 K1103N1095-A1099 WeakPolarHBondContact O-CB 3.15Å; N1095-A1099 PolarHBondContact O-N 2.81Å; F1096-A1099 PolarHBondContact O-N 3.27Å; A1097-A1099 PolarHBondContact O-N 3.26Å; A1099-K1103 VanDerWaalsContact O-CB 3.28Å; A1099-K1103 WeakPolarHBondContact O-CB 3.23Å; A1099-K1103 VanDerWaalsContact O-CG 3.27Å; A1099-K1103 WeakPolarHBondContact O-CG 3.41Å; A1099-K1103 PolarHBondContact O-N 3.23Å
1100K39.1Very low40.5Very low142 Ų142112.4 Ų112.462%0.61763%0.628SS**Hα-helixtrans-77.4-42.7175.3-163.5178.8-177.7-172.90111.3F1096 A1097 V1098 Q1102 K1103 S1104F1096-K1100 VanDerWaalsContact O-CB 3.29Å; F1096-K1100 WeakPolarHBondContact O-CB 3.38Å; F1096-K1100 PolarHBondContact O-N 3.33Å; A1097-K1100 PolarHBondContact O-N 2.77Å; V1098-K1100 VanDerWaalsContact C-N 3.27Å; V1098-K1100 PolarHBondContact O-N 2.99Å; K1100-Q1102 VanDerWaalsContact C-N 3.3Å; K1100-Q1102 PolarHBondContact O-N 2.93Å; K1100-K1103 PolarHBondContact O-N 2.85Å; K1100-S1104 PolarHBondContact O-N 2.74Å
1101V42.7Very low40.6Very low119 Ų119112.7 Ų112.772%0.72163%0.628SS**Hα-helixtrans-62.5-36.6172.8172.20000111.5A1097 V1098 K1103A1097-V1101 WeakPolarHBondContact O-CG2 3.33Å; A1097-V1101 PolarHBondContact O-N 2.97Å; V1098-V1101 PolarHBondContact O-N 3.31Å; V1101-K1103 VanDerWaalsContact C-N 3.3Å; V1101-K1103 PolarHBondContact O-N 2.94Å
1102Q43.8Very low41Very low152 Ų152114.4 Ų114.471%0.7164%0.635SS**THydrogen-bonded Turntrans-78.3-3.4177-71.5177-9.100115V1098 K1100V1098-Q1102 HydrophobicContact CG1-CG 4.43Å; V1098-Q1102 WeakPolarHBondContact O-CB 3.39Å; V1098-Q1102 VanDerWaalsContact O-CG 3.3Å; V1098-Q1102 WeakPolarHBondContact O-CG 3.49Å; V1098-Q1102 PolarHBondContact O-N 2.81Å; K1100-Q1102 VanDerWaalsContact C-N 3.3Å; K1100-Q1102 PolarHBondContact O-N 2.93Å
1103K41.1Very low41.3Very low171 Ų171114.5 Ų114.574%0.74364%0.636SS**THydrogen-bonded Turntrans-123.30.5-175-77.5-174173.6-1760115.9A1099 K1100 V1101 P1105A1099-K1103 VanDerWaalsContact O-CB 3.28Å; A1099-K1103 WeakPolarHBondContact O-CB 3.23Å; A1099-K1103 VanDerWaalsContact O-CG 3.27Å; A1099-K1103 WeakPolarHBondContact O-CG 3.41Å; A1099-K1103 PolarHBondContact O-N 3.23Å; K1100-K1103 PolarHBondContact O-N 2.85Å; V1101-K1103 VanDerWaalsContact C-N 3.3Å; V1101-K1103 PolarHBondContact O-N 2.94Å; K1103-P1105 WeakPolarHBondContact O-CD 3.48Å
1104S34.3Very low41.7Very low91 Ų91117.3 Ų117.364%0.63664%0.644SS**  trans-64.7123168.7-64.20000109.9K1100K1100-S1104 PolarHBondContact O-N 2.74Å
1105P39.5Very low42Very low121 Ų121118.9 Ų118.979%0.78665%0.65SS**  trans-61.7147.5168.4-18.732.7000110.1K1103 E1107K1103-P1105 WeakPolarHBondContact O-CD 3.48Å; P1105-E1107 PolarHBondContact O-N 2.83Å
1106A37.3Very low42.3Very low103 Ų103119.7 Ų119.785%0.85165%0.651SS**  trans-83.1113.7176.800000110.7
1107E33.5Very low42.8Very low180 Ų180116.7 Ų116.784%0.84164%0.641SS**  trans-106.5144.2150.7-70.4-169.115400108.7P1105 E1109P1105-E1107 PolarHBondContact O-N 2.83Å; E1107-E1109 PolarHBondContact O-N 2.72Å
1108P42.5Very low43.2Very low129 Ų129119.9 Ų119.984%0.83865%0.647SS**  trans-94.777.4-157.337-37.2000114.1
1109E38.2Very low43.4Very low176 Ų176123.4 Ų123.482%0.82266%0.664SS**  trans-90.2134.7162.4-68.9-160.4139.200111.8E1107 I1111E1107-E1109 PolarHBondContact O-N 2.72Å; E1109-I1111 VanDerWaalsContact C-N 3.34Å; E1109-I1111 PolarHBondContact O-N 2.99Å
1110V51.3Low43.8Very low149 Ų149127.3 Ų127.390%0.90367%0.674SS**  trans-81.775.2-168.3-173.10000111.2
1111I41.5Very low44.4Very low123 Ų123129.7 Ų129.763%0.63168%0.679SS**  trans-75.1127.3172.4-61.8178.9000109.6E1109 Q1113E1109-I1111 VanDerWaalsContact C-N 3.34Å; E1109-I1111 PolarHBondContact O-N 2.99Å; I1111-Q1113 PolarHBondContact O-N 2.85Å
1112N48.4Very low44.6Very low106 Ų106129.6 Ų129.657%0.56767%0.672SS**  trans-66.1128.3-166.5-164.3-17.1000112.2V1114 Q1115N1112-V1114 PolarHBondContact O-N 2.92Å; N1112-Q1115 PolarHBondContact O-N 3.31Å
1113Q45.7Very low44.7Very low149 Ų149128.6 Ų128.670%0.69667%0.665SS**Hα-helixtrans-61.2-20.6-167.9-156.2175.839.300113.9I1111 N1117I1111-Q1113 PolarHBondContact O-N 2.85Å; Q1113-N1117 PolarHBondContact O-N 3.09Å; Q1113-N1117 PolarHBondContact O-ND2 2.79Å; Q1113-N1117 VanDerWaalsContact O-ND2 3.13Å
1114V48Very low45.2Very low100 Ų100125.2 Ų125.261%0.60666%0.655SS**Hα-helixtrans-65.4-50.7173.4-176.90000111.4N1112 Q1116 N1117 E1118N1112-V1114 PolarHBondContact O-N 2.92Å; V1114-Q1116 VanDerWaalsContact C-N 3.28Å; V1114-Q1116 PolarHBondContact O-N 3.07Å; V1114-N1117 PolarHBondContact O-N 3.33Å; V1114-N1117 VanDerWaalsContact O-N 3.11Å; V1114-E1118 PolarHBondContact O-N 3.06Å
1115Q46.7Very low45.7Very low112 Ų112126.9 Ų126.952%0.52365%0.652SS.*Hα-helixtrans-63.1-34.9-177.8-71.6179.5-43.100112N1112 N1117 E1118 L1119N1112-Q1115 PolarHBondContact O-N 3.31Å; Q1115-N1117 VanDerWaalsContact C-N 3.29Å; Q1115-N1117 PolarHBondContact O-N 3.28Å; Q1115-E1118 PolarHBondContact O-N 2.91Å; Q1115-L1119 WeakPolarHBondContact O-CB 3.31Å; Q1115-L1119 PolarHBondContact O-N 2.95Å
1116Q47.5Very low45.7Very low112 Ų112124.5 Ų124.552%0.52364%0.638SS.*Hα-helixtrans-67.4-30.6178.4-140.3-172.752.600112.6V1114 K1120V1114-Q1116 VanDerWaalsContact C-N 3.28Å; V1114-Q1116 PolarHBondContact O-N 3.07Å; Q1116-K1120 WeakPolarHBondContact O-CG 3.32Å; Q1116-K1120 PolarHBondContact O-N 2.98Å
1117N51.1Low45.8Very low80 Ų80124.8 Ų124.843%0.42862%0.622SS.*Hα-helixtrans-80.3-32.9174.2-75.6-42.4000112.5Q1113 V1114 Q1115 K1120 R1121Q1113-N1117 PolarHBondContact O-N 3.09Å; Q1113-N1117 PolarHBondContact O-ND2 2.79Å; Q1113-N1117 VanDerWaalsContact O-ND2 3.13Å; V1114-N1117 PolarHBondContact O-N 3.33Å; V1114-N1117 VanDerWaalsContact O-N 3.11Å; Q1115-N1117 VanDerWaalsContact C-N 3.29Å; Q1115-N1117 PolarHBondContact O-N 3.28Å; N1117-K1120 PolarHBondContact O-N 2.9Å; N1117-R1121 PolarHBondContact O-N 3.05Å
1118E50.1Low46.3Very low118 Ų118119.5 Ų119.555%0.55160%0.602SS**Hα-helixtrans-66.3-47.7173.8-171162.2-132.400111.7V1114 Q1115 K1120 R1121 M1122V1114-E1118 PolarHBondContact O-N 3.06Å; Q1115-E1118 PolarHBondContact O-N 2.91Å; E1118-K1120 VanDerWaalsContact C-N 3.31Å; E1118-K1120 PolarHBondContact O-N 3.46Å; E1118-R1121 WeakPolarHBondContact O-CB 3.27Å; E1118-R1121 PolarHBondContact O-N 2.75Å; E1118-R1121 VanDerWaalsContact O-N 3.08Å; E1118-M1122 PolarHBondContact O-N 3.08Å
1119L46.5Very low46Very low120 Ų120121.3 Ų121.363%0.62859%0.592SS**Hα-helixtrans-56.8-41.5171.1-86.1159.9000112.3Q1115 M1122 F1123Q1115-L1119 WeakPolarHBondContact O-CB 3.31Å; Q1115-L1119 PolarHBondContact O-N 2.95Å; L1119-M1122 PolarHBondContact O-N 3Å; L1119-F1123 WeakPolarHBondContact O-CB 3.11Å; L1119-F1123 PolarHBondContact O-N 2.99Å
1120K50.8Low45.9Very low121 Ų121118.2 Ų118.253%0.52658%0.58SS.*Hα-helixtrans-61.9-41.7173.7-84.8176.2176.11720112.6Q1116 N1117 E1118 F1123 I1124Q1116-K1120 WeakPolarHBondContact O-CG 3.32Å; Q1116-K1120 PolarHBondContact O-N 2.98Å; N1117-K1120 PolarHBondContact O-N 2.9Å; E1118-K1120 VanDerWaalsContact C-N 3.31Å; E1118-K1120 PolarHBondContact O-N 3.46Å; K1120-F1123 PolarHBondContact O-N 3.35Å; K1120-I1124 VanDerWaalsContact O-CG1 3.29Å; K1120-I1124 WeakPolarHBondContact O-CG1 3.43Å; K1120-I1124 PolarHBondContact O-N 3.41Å
1121R52.7Low45.3Very low192 Ų192117.2 Ų117.273%0.72557%0.568SS**Hα-helixtrans-63.5-47.1175.8-75.6179.4-178156.20.5111.5N1117 E1118 F1123 I1124 Q1125N1117-R1121 PolarHBondContact O-N 3.05Å; E1118-R1121 WeakPolarHBondContact O-CB 3.27Å; E1118-R1121 PolarHBondContact O-N 2.75Å; E1118-R1121 VanDerWaalsContact O-N 3.08Å; R1121-F1123 VanDerWaalsContact C-N 3.32Å; R1121-F1123 PolarHBondContact O-N 3.44Å; R1121-I1124 PolarHBondContact O-N 2.71Å; R1121-Q1125 VanDerWaalsContact O-CB 3.31Å; R1121-Q1125 WeakPolarHBondContact O-CB 3.22Å; R1121-Q1125 PolarHBondContact O-N 2.72Å
1122M46.1Very low45Very low116 Ų116118.6 Ų118.657%0.57157%0.572SS**Hα-helixtrans-60.1-42.2176-68.5-172.673.800111.8E1118 L1119 Q1125 C1126E1118-M1122 PolarHBondContact O-N 3.08Å; L1119-M1122 PolarHBondContact O-N 3Å; M1122-Q1125 PolarHBondContact O-N 3.28Å; M1122-C1126 WeakPolarHBondContact O-CB 3.42Å; M1122-C1126 PolarHBondContact O-N 2.95Å; M1122-C1126 PolarHBondContact O-SG 3.08Å
1123F45.5Very low44.3Very low131 Ų131122.5 Ų122.558%0.57559%0.591SS**Hα-helixtrans-64.7-43.2179.2-157.3-87.3000112.2L1119 K1120 R1121 C1126 Q1127L1119-F1123 WeakPolarHBondContact O-CB 3.11Å; L1119-F1123 PolarHBondContact O-N 2.99Å; K1120-F1123 PolarHBondContact O-N 3.35Å; R1121-F1123 VanDerWaalsContact C-N 3.32Å; R1121-F1123 PolarHBondContact O-N 3.44Å; F1123-C1126 PolarHBondContact O-N 3.2Å; F1123-Q1127 WeakPolarHBondContact O-CB 3.39Å; F1123-Q1127 PolarHBondContact O-N 2.71Å
1124I52.8Low44.2Very low101 Ų101121.2 Ų121.252%0.51859%0.585SS.*Hα-helixtrans-62.5-43.8173.3-69.5165.9000110.4K1120 R1121 C1126 Q1127 T1128K1120-I1124 VanDerWaalsContact O-CG1 3.29Å; K1120-I1124 WeakPolarHBondContact O-CG1 3.43Å; K1120-I1124 PolarHBondContact O-N 3.41Å; R1121-I1124 PolarHBondContact O-N 2.71Å; I1124-C1126 PolarHBondContact O-N 2.82Å; I1124-Q1127 CarbonylContact O-C 3.59Å; I1124-Q1127 WeakPolarHBondContact O-CB 3.18Å; I1124-Q1127 PolarHBondContact O-N 2.88Å; I1124-Q1127 VanDerWaalsContact O-N 3.14Å; I1124-T1128 PolarHBondContact O-N 2.86Å; I1124-T1128 PolarHBondContact O-OG1 3.36Å; I1124-T1128 VanDerWaalsContact O-OG1 3.04Å
1125Q44.3Very low44Very low125 Ų125122.3 Ų122.358%0.58458%0.584SS**Hα-helixtrans-66.7-36.7-178.9-163.5172.418.300112.6R1121 M1122 R1129R1121-Q1125 VanDerWaalsContact O-CB 3.31Å; R1121-Q1125 WeakPolarHBondContact O-CB 3.22Å; R1121-Q1125 PolarHBondContact O-N 2.72Å; M1122-Q1125 PolarHBondContact O-N 3.28Å; Q1125-R1129 PolarHBondContact O-N 2.68Å; Q1125-R1129 VanDerWaalsContact O-N 3.09Å
1126C40Very low43.9Very low72 Ų72122.9 Ų122.949%0.48659%0.588SS.*Hα-helixtrans-65.3-43.9168.6-75.40000111.7M1122 F1123 I1124 T1128 R1129 I1130M1122-C1126 WeakPolarHBondContact O-CB 3.42Å; M1122-C1126 PolarHBondContact O-N 2.95Å; M1122-C1126 PolarHBondContact O-SG 3.08Å; F1123-C1126 PolarHBondContact O-N 3.2Å; I1124-C1126 PolarHBondContact O-N 2.82Å; C1126-T1128 VanDerWaalsContact C-N 3.35Å; C1126-T1128 PolarHBondContact O-N 3.42Å; C1126-R1129 PolarHBondContact O-N 2.61Å; C1126-I1130 WeakPolarHBondContact O-CB 3.39Å; C1126-I1130 WeakPolarHBondContact O-CD1 3.39Å; C1126-I1130 VanDerWaalsContact O-CG1 3.28Å; C1126-I1130 WeakPolarHBondContact O-CG1 3.48Å; C1126-I1130 PolarHBondContact O-N 2.91Å
1127Q39.6Very low43.7Very low109 Ų109123.5 Ų123.551%0.50959%0.592SS.*Hα-helixtrans-61.3-41.4176.8-174.4178.84.700111.9F1123 I1124 I1130 I1131F1123-Q1127 WeakPolarHBondContact O-CB 3.39Å; F1123-Q1127 PolarHBondContact O-N 2.71Å; I1124-Q1127 CarbonylContact O-C 3.59Å; I1124-Q1127 WeakPolarHBondContact O-CB 3.18Å; I1124-Q1127 PolarHBondContact O-N 2.88Å; I1124-Q1127 VanDerWaalsContact O-N 3.14Å; Q1127-I1130 PolarHBondContact O-N 2.95Å; Q1127-I1131 HydrophobicContact CG-CD1 4.01Å; Q1127-I1131 WeakPolarHBondContact O-CD1 3.2Å; Q1127-I1131 VanDerWaalsContact O-CG1 3.31Å; Q1127-I1131 WeakPolarHBondContact O-CG1 3.45Å; Q1127-I1131 PolarHBondContact O-N 2.73Å; Q1127-I1131 VanDerWaalsContact O-N 3.16Å
1128T42.1Very low43.2Very low69 Ų69126.3 Ų126.342%0.42360%0.602SS.*Hα-helixtrans-63-44.3174.6-53.10000111.3I1124 C1126 I1130 I1131 Q1132I1124-T1128 PolarHBondContact O-N 2.86Å; I1124-T1128 PolarHBondContact O-OG1 3.36Å; I1124-T1128 VanDerWaalsContact O-OG1 3.04Å; C1126-T1128 VanDerWaalsContact C-N 3.35Å; C1126-T1128 PolarHBondContact O-N 3.42Å; T1128-I1130 VanDerWaalsContact C-N 3.34Å; T1128-I1130 PolarHBondContact O-N 3.32Å; T1128-I1131 PolarHBondContact O-N 2.95Å; T1128-I1131 VanDerWaalsContact O-N 3.12Å; T1128-Q1132 WeakPolarHBondContact O-CG 3.49Å; T1128-Q1132 PolarHBondContact O-N 2.98Å; T1128-Q1132 VanDerWaalsContact O-N 3.16Å
1129R36.7Very low42.7Very low167 Ų167126.8 Ų126.863%0.6361%0.605SS**Hα-helixtrans-63.5-35.3175.7-101.7176.8165.5156.8-5.5113.4Q1125 C1126 I1131 Q1132 I1133Q1125-R1129 PolarHBondContact O-N 2.68Å; Q1125-R1129 VanDerWaalsContact O-N 3.09Å; C1126-R1129 PolarHBondContact O-N 2.61Å; R1129-I1131 PolarHBondContact O-N 2.75Å; R1129-Q1132 PolarHBondContact O-N 3.03Å; R1129-I1133 WeakPolarHBondContact O-CG1 3.36Å; R1129-I1133 PolarHBondContact O-N 2.67Å
1130I37.4Very low42.5Very low111 Ų111127.3 Ų127.357%0.56960%0.603SS**THydrogen-bonded Turntrans-78.3-3.8176.8-66.1164.2000112.4C1126 Q1127 T1128C1126-I1130 WeakPolarHBondContact O-CB 3.39Å; C1126-I1130 WeakPolarHBondContact O-CD1 3.39Å; C1126-I1130 VanDerWaalsContact O-CG1 3.28Å; C1126-I1130 WeakPolarHBondContact O-CG1 3.48Å; C1126-I1130 PolarHBondContact O-N 2.91Å; Q1127-I1130 PolarHBondContact O-N 2.95Å; T1128-I1130 VanDerWaalsContact C-N 3.34Å; T1128-I1130 PolarHBondContact O-N 3.32Å
1131I38.1Very low41.8Very low128 Ų128127.8 Ų127.866%0.65661%0.609SS**THydrogen-bonded Turntrans-104.5-8.3169.6-67.5166.8000110.9Q1127 T1128 R1129Q1127-I1131 HydrophobicContact CG-CD1 4.01Å; Q1127-I1131 WeakPolarHBondContact O-CD1 3.2Å; Q1127-I1131 VanDerWaalsContact O-CG1 3.31Å; Q1127-I1131 WeakPolarHBondContact O-CG1 3.45Å; Q1127-I1131 PolarHBondContact O-N 2.73Å; Q1127-I1131 VanDerWaalsContact O-N 3.16Å; T1128-I1131 PolarHBondContact O-N 2.95Å; T1128-I1131 VanDerWaalsContact O-N 3.12Å; R1129-I1131 PolarHBondContact O-N 2.75Å
1132Q35.2Very low40.9Very low151 Ų151122.4 Ų122.471%0.70660%0.6SS**  trans-104.72175.1-69.2178.3-4900112.9T1128 R1129T1128-Q1132 WeakPolarHBondContact O-CG 3.49Å; T1128-Q1132 PolarHBondContact O-N 2.98Å; T1128-Q1132 VanDerWaalsContact O-N 3.16Å; R1129-Q1132 PolarHBondContact O-N 3.03Å
1133I33.5Very low40.5Very low189 Ų189123 Ų12397%0.96960%0.602SS**  trans-124.90174.1-60.5166.4000106.6R1129R1129-I1133 WeakPolarHBondContact O-CG1 3.36Å; R1129-I1133 PolarHBondContact O-N 2.67Å

Retrieved 1,133 of 1,133 residues in 193.3 ms (Link to these results)