A0A096NU03_PAPAN Loading...

Arylsulfatase G

AlphaFold DB , UniProt , Accession A0A096NU03, Species PAPAN (Papio anubis, Olive baboon), Gene ARSG, Length 525 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M35.6Very low36.5Very low252 Ų252162.3 Ų162.3100%1.24186%0.859SS**  0113.30-157.5169-93.400106.5
2G33.3Very low36.1Very low79 Ų79155 Ų15581%0.81485%0.852SS**  trans95.688.1173.400000116.7
3W36.8Very low36.5Very low227 Ų227154.1 Ų154.186%0.8685%0.853SS**  trans-99.7132.3160.3-100.18.7000108.4F5W3-F5 HydrophobicContact CD2-CD2 4.43Å; W3-F5 AromaticContact CD2-CE2 3.77Å; W3-F5 HydrophobicContact CD2-CE2 3.77Å; W3-F5 HydrophobicContact CE3-CD2 4.05Å; W3-F5 AromaticContact CE3-CE2 3.37Å; W3-F5 HydrophobicContact CE3-CE2 3.37Å; W3-F5 HydrophobicContact CE3-CZ 4.37Å; W3-F5 HydrophobicContact CG-CE2 4.42Å; W3-F5 HydrophobicContact CH2-CE2 4.13Å; W3-F5 HydrophobicContact CH2-CZ 4.41Å; W3-F5 AromaticContact CZ3-CE2 3.56Å; W3-F5 HydrophobicContact CZ3-CE2 3.56Å; W3-F5 HydrophobicContact CZ3-CZ 4.14Å
4L38Very low36.4Very low181 Ų181151.6 Ų151.695%0.94885%0.852SS**  trans-116.2112.4167.4-105.8119.6000108.9
5F38.9Very low37.1Very low141 Ų141154.7 Ų154.762%0.61885%0.853SS**  trans-102.1128.7170.2-90.4-93.2000109.1W3W3-F5 HydrophobicContact CD2-CD2 4.43Å; W3-F5 AromaticContact CD2-CE2 3.77Å; W3-F5 HydrophobicContact CD2-CE2 3.77Å; W3-F5 HydrophobicContact CE3-CD2 4.05Å; W3-F5 AromaticContact CE3-CE2 3.37Å; W3-F5 HydrophobicContact CE3-CE2 3.37Å; W3-F5 HydrophobicContact CE3-CZ 4.37Å; W3-F5 HydrophobicContact CG-CE2 4.42Å; W3-F5 HydrophobicContact CH2-CE2 4.13Å; W3-F5 HydrophobicContact CH2-CZ 4.41Å; W3-F5 AromaticContact CZ3-CE2 3.56Å; W3-F5 HydrophobicContact CZ3-CE2 3.56Å; W3-F5 HydrophobicContact CZ3-CZ 4.14Å
6L34.2Very low37.4Very low172 Ų172152.4 Ų152.490%0.90185%0.851SS**  trans-100.5110.6164.4-163.774.3000107.7
7K33.7Very low38Very low177 Ų177147.9 Ų147.977%0.7785%0.848SS**  trans-109121.7171.6-77-172.6176.7-176.70108.8
8V39.1Very low38.2Very low133 Ų133149.7 Ų149.781%0.80684%0.844SS**  trans-89.5126165.9175.50000107.8
9L36.1Very low38.4Very low159 Ų159151.3 Ų151.383%0.83285%0.85SS**  trans-92.2127.2178.8-111.5138.2000109.4
10L35.9Very low38.3Very low171 Ų171153.5 Ų153.590%0.89585%0.845SS**  trans-121.3108.7161-104154.8000107.3
11A39.4Very low38.5Very low93 Ų93151.4 Ų151.477%0.76984%0.839SS**  trans-89.1123.5175.400000109.3
12G32.4Very low38.6Very low75 Ų75147.3 Ų147.377%0.77382%0.822SS**  trans-151.497.9168.700000108.4
13V40.6Very low39Very low143 Ų143148.5 Ų148.587%0.86781%0.813SS**  trans-81.9122.4176.7176.70000108.2
14S35.6Very low38.8Very low120 Ų120144.5 Ų144.584%0.83981%0.808SS**  trans-146.2135.8152.7-155.10000111.1S16S14-S16 PolarHBondContact O-N 3.5Å
15F46.4Very low38.8Very low198 Ų198144.1 Ų144.187%0.86880%0.799SS**  trans-57.1119.7-174.7-109-114.8000112.9
16S41.5Very low38.6Very low117 Ų117142.9 Ų142.982%0.81881%0.807SS**  trans-179.8121.7137.1-83.10000109.5S14 F18S14-S16 PolarHBondContact O-N 3.5Å; S16-F18 PolarHBondContact O-N 3.35Å
17G49Very low39Very low77 Ų77141.5 Ų141.579%0.79480%0.799SS**  trans-69.7118.7-175.800000112.8
18F41.1Very low39.2Very low179 Ų179138 Ų13879%0.78580%0.796SS**  trans-142.8109.1148.1-100.9-87.5000106.9S16 Y20S16-F18 PolarHBondContact O-N 3.35Å; F18-Y20 HydrophobicContact CB-CD2 4.45Å; F18-Y20 HydrophobicContact CB-CE2 4.11Å; F18-Y20 PolarHBondContact O-N 3.14Å; F18-Y20 VanDerWaalsContact O-N 3.14Å
19L41.6Very low39.1Very low180 Ų180134.3 Ų134.394%0.94279%0.786SS**  trans-72.399171.9-84.1156.6000108.2
20Y37.3Very low39.2Very low195 Ų195135.6 Ų135.677%0.76579%0.785SS**  trans-79.8127.1162.3-73.9-86.4000108.4F18 L22F18-Y20 HydrophobicContact CB-CD2 4.45Å; F18-Y20 HydrophobicContact CB-CE2 4.11Å; F18-Y20 PolarHBondContact O-N 3.14Å; F18-Y20 VanDerWaalsContact O-N 3.14Å; Y20-L22 PolarHBondContact O-N 2.9Å; Y20-L22 VanDerWaalsContact O-N 3.13Å
21P41Very low39.3Very low110 Ų110134.1 Ų134.171%0.71478%0.783SS**  trans-67.2115.8168.528.1-29000107.3V23P21-V23 PolarHBondContact O-N 3.13Å
22L37.9Very low39.7Very low167 Ų167140 Ų14087%0.87479%0.785SS**  trans-65.392.4163.7-83.4160.1000106.9Y20 D24Y20-L22 PolarHBondContact O-N 2.9Å; Y20-L22 VanDerWaalsContact O-N 3.13Å; L22-D24 VanDerWaalsContact C-N 3.35Å; L22-D24 PolarHBondContact O-N 2.84Å; L22-D24 VanDerWaalsContact O-N 3.11Å
23V41.7Very low41.2Very low104 Ų104138.9 Ų138.963%0.6377%0.774SS**  trans-72.298.2164.6-175.40000105.6P21 F25P21-V23 PolarHBondContact O-N 3.13Å; V23-F25 VanDerWaalsContact C-N 3.25Å; V23-F25 HydrophobicContact CG1-CD2 4.01Å; V23-F25 HydrophobicContact CG1-CE2 4.3Å; V23-F25 PolarHBondContact O-N 2.86Å
24D34.2Very low43.3Very low143 Ų143139 Ų13977%0.76576%0.759SS**  trans-62.293.3165.3-92.6-29.3000107.7L22 C26L22-D24 VanDerWaalsContact C-N 3.35Å; L22-D24 PolarHBondContact O-N 2.84Å; L22-D24 VanDerWaalsContact O-N 3.11Å; D24-C26 PolarHBondContact O-N 3.11Å
25F38Very low46.1Very low173 Ų173135.9 Ų135.976%0.75973%0.73SS**  trans-67.284.8162.2-107.1-88.4000107.2V23 I27V23-F25 VanDerWaalsContact C-N 3.25Å; V23-F25 HydrophobicContact CG1-CD2 4.01Å; V23-F25 HydrophobicContact CG1-CE2 4.3Å; V23-F25 PolarHBondContact O-N 2.86Å; F25-I27 HydrophobicContact CB-CG1 4.49Å; F25-I27 HydrophobicContact CD1-CG1 4.37Å; F25-I27 PolarHBondContact O-N 2.81Å
26C34.9Very low48.5Very low115 Ų115126.9 Ų126.978%0.77769%0.691SS**  trans-62.488.5154-81.20000106.8D24 S28D24-C26 PolarHBondContact O-N 3.11Å; C26-S28 PolarHBondContact O-N 2.83Å
27I40.7Very low51.3Low143 Ų143121.3 Ų121.373%0.73365%0.652SS**  trans-66.686.8160.3-58.4175.7000104.8F25 G29F25-I27 HydrophobicContact CB-CG1 4.49Å; F25-I27 HydrophobicContact CD1-CG1 4.37Å; F25-I27 PolarHBondContact O-N 2.81Å; I27-G29 PolarHBondContact O-N 2.83Å
28S38.4Very low53.6Low102 Ų102117.7 Ų117.771%0.71362%0.615SS**  trans-61.890.8154.3-174.90000105.1C26 K30C26-S28 PolarHBondContact O-N 2.83Å; S28-K30 PolarHBondContact O-N 2.97Å
29G38.1Very low56.4Low57 Ų57109.1 Ų109.159%0.58858%0.578SS**  trans-6479.5166.700000107.4I27 T31I27-G29 PolarHBondContact O-N 2.83Å; G29-T31 VanDerWaalsContact C-N 3.33Å; G29-T31 PolarHBondContact O-N 2.75Å
30K36.9Very low59.1Low186 Ų186100.7 Ų100.781%0.80953%0.533SS*.  trans-51.9113.4149.6-81.1-174.1177.7179.50103.5S28 R32S28-K30 PolarHBondContact O-N 2.97Å; K30-R32 PolarHBondContact O-N 2.93Å
31T37.7Very low62.1Low139 Ų13991.4 Ų91.485%0.85350%0.497SS*.  trans-56.387.5164.446.10000105.9G29 G33G29-T31 VanDerWaalsContact C-N 3.33Å; G29-T31 PolarHBondContact O-N 2.75Å; T31-G33 PolarHBondContact O-N 2.67Å
32R49.5Very low64.8Low216 Ų21686.2 Ų86.282%0.81546%0.463SS*.  trans-61.6108174.7-147.1177.4-170.2179.73.3102.8K30 R34K30-R32 PolarHBondContact O-N 2.93Å; R32-R34 PolarHBondContact O-N 3.22Å
33G63.3Low67.7Low53 Ų5378.2 Ų78.255%0.54642%0.421SS..PPolyproline II helixtrans-48.3134.8-17700000108.9T31 K35T31-G33 PolarHBondContact O-N 2.67Å; G33-K35 PolarHBondContact O-N 3.3Å
34R84.4Confident70.4Confident146 Ų14673.3 Ų73.355%0.55139%0.391SS*.PPolyproline II helixtrans-53.5127.7-178.9-173.4175.9172.3166.7-1.3108.3R32R32-R34 PolarHBondContact O-N 3.22Å
35K94.8Very high73.5Confident53 Ų5366.7 Ų66.723%0.2336%0.356CS..PPolyproline II helixtrans-60.4140175.4-69.4-170178.4-166.90109.1G33 A128 Y130 P240 N294 A376G33-K35 PolarHBondContact O-N 3.3Å; K35-A128 PolarHBondContact NZ-O 2.92Å; K35-Y130 HydrophobicContact CD-CE2 3.91Å; K35-P240 HydrophobicContact CB-CB 4.1Å; K35-P240 HydrophobicContact CB-CG 4.1Å; K35-P240 HydrophobicContact CD-CG 4.48Å; K35-N294 PolarHBondContact O-ND2 2.86Å; K35-A376 WeakPolarHBondContact CE-O 3.02Å; K35-A376 PolarHBondContact NZ-O 2.99Å
36P97.6Very high76.3Confident9 Ų958.5 Ų58.56%0.05832%0.32CS..PPolyproline II helixtrans-70.8153.918031-35.7000111F38 Y130 N294 W349 L375P36-F38 HydrophobicContact CB-CE1 4.41Å; P36-F38 HydrophobicContact CB-CZ 4.42Å; P36-F38 HydrophobicContact CG-CE1 3.95Å; P36-F38 HydrophobicContact CG-CE2 4.32Å; P36-F38 HydrophobicContact CG-CZ 3.6Å; P36-Y130 WeakPolarHBondContact O-CE1 3.39Å; P36-Y130 PolarHBondContact O-OH 2.96Å; P36-N294 CarbonylContact C-O 3.6Å; P36-N294 WeakPolarHBondContact CA-O 3.17Å; P36-W349 HydrophobicContact CB-CH2 3.51Å; P36-W349 HydrophobicContact CB-CZ2 3.66Å; P36-W349 HydrophobicContact CB-CZ3 4.45Å; P36-W349 HydrophobicContact CG-CH2 3.94Å; P36-L375 WeakPolarHBondContact CD-O 3.26Å; P36-L375 HydrophobicContact CG-CB 4.47Å
37N98.8Very high79.3Confident0 Ų053 Ų530%028%0.283CS..EExtended strand (participates in β ladder)trans-86.1154.1165.4-51.2-46000109.4P240 F241 N294 T295 F296N37-P240 WeakPolarHBondContact OD1-CA 3.48Å; N37-F241 CarbonylContact C-O 3.52Å; N37-F241 WeakPolarHBondContact CA-O 3.4Å; N37-F241 HydrophobicContact CB-CD1 3.9Å; N37-F241 HydrophobicContact CB-CD2 4.1Å; N37-F241 HydrophobicContact CB-CE1 3.65Å; N37-F241 HydrophobicContact CB-CE2 3.85Å; N37-F241 HydrophobicContact CB-CG 4.12Å; N37-F241 HydrophobicContact CB-CZ 3.61Å; N37-F241 WeakPolarHBondContact ND2-CE1 3.36Å; N37-F241 WeakPolarHBondContact OD1-CD1 3.23Å; N37-F241 PolarHBondContact OD1-N 3.48Å; N37-N294 PolarHBondContact N-O 3.02Å; N37-N294 PolarHBondContact ND2-O 2.72Å; N37-T295 HydrophobicContact CB-CG2 3.86Å; N37-T295 PolarHBondContact ND2-OG1 3.37Å; N37-T295 VanDerWaalsContact ND2-OG1 3.12Å; N37-T295 WeakPolarHBondContact O-CA 3.21Å; N37-F296 PolarHBondContact O-N 3.28Å
38F98.9Very high82.1Confident1 Ų147.2 Ų47.20%0.00425%0.252CS..EExtended strand (participates in β ladder)trans-126.2131.9178.8-56.7-68.5000110.5P36 L125 Y130 F241 L242 L243 F296 V372 L375 A376P36-F38 HydrophobicContact CB-CE1 4.41Å; P36-F38 HydrophobicContact CB-CZ 4.42Å; P36-F38 HydrophobicContact CG-CE1 3.95Å; P36-F38 HydrophobicContact CG-CE2 4.32Å; P36-F38 HydrophobicContact CG-CZ 3.6Å; F38-L125 HydrophobicContact CD2-CD1 3.92Å; F38-L125 HydrophobicContact CE2-CD1 4.33Å; F38-L125 HydrophobicContact CE2-CD2 4.42Å; F38-Y130 HydrophobicContact CD2-CD1 4.3Å; F38-Y130 AromaticContact CD2-CE1 3.52Å; F38-Y130 HydrophobicContact CD2-CE1 3.52Å; F38-Y130 AromaticContact CE2-CE1 3.52Å; F38-Y130 HydrophobicContact CE2-CE1 3.52Å; F38-Y130 AromaticContact CE2-CZ 3.62Å; F38-Y130 VanDerWaalsContact CE2-OH 3.29Å; F38-Y130 WeakPolarHBondContact CE2-OH 3.35Å; F38-F241 PolarHBondContact N-O 2.87Å; F38-L242 HydrophobicContact CB-CD1 3.92Å; F38-L242 CarbonylContact O-C 3.57Å; F38-L242 WeakPolarHBondContact O-CA 3.01Å; F38-L243 PolarHBondContact O-N 3.13Å; F38-F296 HydrophobicContact CD1-CB 4.08Å; F38-F296 AromaticContact CD1-CD1 3.95Å; F38-F296 HydrophobicContact CD1-CD1 3.95Å; F38-F296 HydrophobicContact CE1-CB 4.45Å; F38-F296 HydrophobicContact CE1-CD1 4.26Å; F38-V372 HydrophobicContact CD1-CG1 4.05Å; F38-V372 HydrophobicContact CD1-CG2 4.33Å; F38-V372 HydrophobicContact CD2-CG1 3.66Å; F38-V372 HydrophobicContact CE1-CG1 4.1Å; F38-V372 HydrophobicContact CE2-CG1 3.71Å; F38-V372 HydrophobicContact CG-CG1 3.81Å; F38-V372 HydrophobicContact CZ-CG1 3.92Å; F38-L375 HydrophobicContact CE1-CB 3.82Å; F38-L375 HydrophobicContact CE1-CD1 4.12Å; F38-L375 HydrophobicContact CZ-CB 3.7Å; F38-A376 HydrophobicContact CE2-CB 3.88Å; F38-A376 HydrophobicContact CZ-CB 4.2Å
39V98.9Very high84.9Confident0 Ų042.4 Ų42.40%022%0.218CC..EExtended strand (participates in β ladder)trans-124.4110.2168.2179.70000107.6I41 F241 L243 I283 V287 T295 F296 L297 W298V39-I41 HydrophobicContact CG1-CD1 4.28Å; V39-I41 HydrophobicContact CG1-CG1 3.98Å; V39-F241 HydrophobicContact CG2-CE2 3.8Å; V39-L243 CarbonylContact C-O 3.56Å; V39-L243 WeakPolarHBondContact CA-O 3.39Å; V39-L243 HydrophobicContact CG1-CD2 4.47Å; V39-L243 HydrophobicContact CG2-CB 4.26Å; V39-I283 HydrophobicContact CG1-CG2 3.96Å; V39-V287 HydrophobicContact CG2-CG2 4.02Å; V39-T295 HydrophobicContact CG2-CG2 3.84Å; V39-F296 PolarHBondContact N-O 2.92Å; V39-L297 HydrophobicContact CB-CD1 4Å; V39-L297 HydrophobicContact CB-CG 3.95Å; V39-L297 HydrophobicContact CG1-CG 4.34Å; V39-L297 HydrophobicContact CG2-CD1 4.24Å; V39-L297 VanDerWaalsContact O-CA 3.31Å; V39-L297 WeakPolarHBondContact O-CA 3.42Å; V39-W298 PolarHBondContact O-N 3Å
40I98.9Very high87.8Confident3 Ų340 Ų402%0.01519%0.192CC..EExtended strand (participates in β ladder)trans-107.3118.2179.9-56.9168.3000106.9L91 L121 L242 L243 Y244 V245 W298 I368 V372I40-L91 HydrophobicContact CG2-CD1 4.43Å; I40-L121 HydrophobicContact CD1-CD2 3.72Å; I40-L242 HydrophobicContact CD1-CD1 3.85Å; I40-L242 HydrophobicContact CG1-CD1 4.36Å; I40-L243 PolarHBondContact N-O 3.47Å; I40-Y244 HydrophobicContact CB-CD2 4.23Å; I40-Y244 HydrophobicContact CG2-CD2 4.16Å; I40-Y244 HydrophobicContact CG2-CE2 4.47Å; I40-Y244 CarbonylContact O-C 3.53Å; I40-Y244 WeakPolarHBondContact O-CA 3.1Å; I40-V245 PolarHBondContact O-N 3.18Å; I40-W298 CarbonylContact C-O 3.55Å; I40-W298 WeakPolarHBondContact CA-O 3.49Å; I40-I368 HydrophobicContact CD1-CG2 3.71Å; I40-I368 HydrophobicContact CG1-CG2 4.43Å; I40-I368 HydrophobicContact CG2-CG2 4.44Å; I40-V372 HydrophobicContact CD1-CG2 4.26Å
41I98.9Very high90.7Very high0 Ų031.1 Ų31.10%015%0.153CC..EExtended strand (participates in β ladder)trans-111.2122.4-179.2-52.9177.9000108.3V39 V245 L247 V280 I283 W298 F299 T300V39-I41 HydrophobicContact CG1-CD1 4.28Å; V39-I41 HydrophobicContact CG1-CG1 3.98Å; I41-V245 CarbonylContact C-O 3.17Å; I41-V245 WeakPolarHBondContact CA-O 3.37Å; I41-V245 HydrophobicContact CG1-CB 4.21Å; I41-V245 HydrophobicContact CG1-CG2 4.42Å; I41-V245 HydrophobicContact CG2-CB 4.44Å; I41-L247 HydrophobicContact CG2-CD1 3.91Å; I41-L247 HydrophobicContact CG2-CG 4.24Å; I41-V280 HydrophobicContact CD1-CG1 3.93Å; I41-V280 HydrophobicContact CD1-CG2 4.45Å; I41-V280 HydrophobicContact CG2-CG2 4.08Å; I41-I283 HydrophobicContact CD1-CG2 4.23Å; I41-W298 PolarHBondContact N-O 2.7Å; I41-F299 HydrophobicContact CB-CD2 3.94Å; I41-F299 HydrophobicContact CG2-CD2 3.69Å; I41-F299 HydrophobicContact CG2-CE2 4.08Å; I41-F299 CarbonylContact O-C 3.56Å; I41-F299 WeakPolarHBondContact O-CA 3.16Å; I41-T300 PolarHBondContact O-N 3.35Å
42L98.9Very high93.6Very high0 Ų025.1 Ų25.10%012%0.119CC..EExtended strand (participates in β ladder)trans-119.2113.3-178.4-172.971.3000109.9R88 L91 Y244 V245 A246 L247 T300 D302L42-R88 HydrophobicContact CD2-CG 3.85Å; L42-L91 HydrophobicContact CD1-CD1 4Å; L42-L91 HydrophobicContact CD2-CD1 4.1Å; L42-Y244 HydrophobicContact CB-CE2 3.99Å; L42-Y244 HydrophobicContact CD2-CE2 4.24Å; L42-Y244 WeakPolarHBondContact CD2-OH 3.45Å; L42-V245 PolarHBondContact N-O 3.29Å; L42-A246 CarbonylContact O-C 3.5Å; L42-L247 PolarHBondContact O-N 3.37Å; L42-T300 CarbonylContact C-O 3.56Å; L42-T300 WeakPolarHBondContact CA-O 3.4Å; L42-T300 HydrophobicContact CD1-CG2 3.64Å; L42-D302 HydrophobicContact CD1-CB 4.01Å; L42-D302 HydrophobicContact CD2-CB 3.88Å; L42-D302 HydrophobicContact CG-CB 3.99Å
43A98.6Very high95.9Very high0 Ų016.3 Ų16.30%09%0.093CC..EExtended strand (participates in β ladder)trans-79.6151.4170.500000111.3M46 M276 F299 T300 G301 D302A43-M46 HydrophobicContact CB-CB 3.73Å; A43-M46 HydrophobicContact CB-CG 4.47Å; A43-M46 HydrophobicContact CB-SD 3.96Å; A43-M276 HydrophobicContact CB-SD 4.01Å; A43-F299 HydrophobicContact CB-CE2 4.39Å; A43-F299 HydrophobicContact CB-CZ 4.13Å; A43-T300 PolarHBondContact N-O 2.94Å; A43-G301 CarbonylContact O-C 3.24Å; A43-G301 WeakPolarHBondContact O-CA 3.38Å; A43-D302 PolarHBondContact O-N 3.38Å
44D98.6Very high97.5Very high0 Ų014.6 Ų14.60%07%0.071CC..SBendtrans-104124.6-178.5-159.211.6000109.5M46 C84 R88 K137 H249 M250 H251 D302D44-M46 PolarHBondContact O-N 3.33Å; D44-M46 VanDerWaalsContact O-N 3.13Å; D44-C84 PolarHBondContact OD1-SG 2.89Å; D44-C84 VanDerWaalsContact OD1-SG 3.39Å; D44-R88 IonicContact OD1-NH2 3.54Å; D44-R88 PolarHBondContact OD1-NH2 2.87Å; D44-R88 IonicContact OD2-NH2 3.18Å; D44-K137 IonicContact OD1-NZ 2.75Å; D44-K137 PolarHBondContact OD1-NZ 3.36Å; D44-K137 WeakPolarHBondContact OD2-CD 3.45Å; D44-K137 WeakPolarHBondContact OD2-CE 3.26Å; D44-K137 IonicContact OD2-NZ 2.74Å; D44-K137 PolarHBondContact OD2-NZ 3.07Å; D44-H249 WeakPolarHBondContact CB-O 3.45Å; D44-H249 PolarHBondContact N-O 2.93Å; D44-H249 CarbonylContact O-C 3.46Å; D44-M250 CarbonylContact O-C 3.47Å; D44-M250 WeakPolarHBondContact O-CA 3.41Å; D44-M250 PolarHBondContact O-N 2.81Å; D44-H251 HydrophobicContact CB-CB 3.98Å; D44-H251 PolarHBondContact O-N 2.96Å; D44-H251 IonicContact OD1-CD2 3.92Å; D44-H251 VanDerWaalsContact OD2-CB 3.23Å; D44-H251 WeakPolarHBondContact OD2-CB 3.44Å; D44-H251 IonicContact OD2-CD2 2.73Å; D44-H251 IonicContact OD2-CG 2.72Å; D44-D302 WeakPolarHBondContact CA-OD1 3.23Å; D44-D302 VanDerWaalsContact OD1-OD2 3.08Å
45D98.3Very high98.1Very high5 Ų511.3 Ų11.33%0.0276%0.058CC..SBendtrans56.826.5-179.8-63.7-2.5000115.6H251 D302 N303 P305 K333D45-H251 VanDerWaalsContact CG-CD2 3.44Å; D45-H251 IonicContact OD1-CD2 3.79Å; D45-H251 IonicContact OD2-CD2 3.23Å; D45-H251 PolarHBondContact OD2-CD2 3.29Å; D45-H251 IonicContact OD2-CG 3.79Å; D45-H251 IonicContact OD2-NE2 3.54Å; D45-D302 PolarHBondContact N-OD1 3.12Å; D45-D302 VanDerWaalsContact N-OD1 3.1Å; D45-N303 PolarHBondContact OD1-ND2 3.21Å; D45-P305 WeakPolarHBondContact O-CA 3.13Å; D45-K333 WeakPolarHBondContact OD1-CD 3.12Å; D45-K333 WeakPolarHBondContact OD1-CE 3.35Å; D45-K333 IonicContact OD1-NZ 3.28Å; D45-K333 PolarHBondContact OD1-NZ 3.48Å; D45-K333 IonicContact OD2-NZ 3.77Å; D45-K333 PolarHBondContact OD2-NZ 3.09Å
46M97.8Very high98.1Very high0 Ų012 Ų120%07%0.074CC..  trans-85.8119.3175.6-172.6-178-177.600110.6A43 D44 D50 L51 L64 L273 M276 F299 N303 P344A43-M46 HydrophobicContact CB-CB 3.73Å; A43-M46 HydrophobicContact CB-CG 4.47Å; A43-M46 HydrophobicContact CB-SD 3.96Å; D44-M46 PolarHBondContact O-N 3.33Å; D44-M46 VanDerWaalsContact O-N 3.13Å; M46-D50 HydrophobicContact CE-CB 3.75Å; M46-D50 WeakPolarHBondContact CE-O 3.32Å; M46-D50 HydrophobicContact CG-CB 3.78Å; M46-L51 HydrophobicContact CE-CB 4.15Å; M46-L64 HydrophobicContact CE-CD1 4.44Å; M46-L273 HydrophobicContact CE-CD1 4.12Å; M46-M276 HydrophobicContact CE-CE 4.14Å; M46-M276 HydrophobicContact SD-CE 3.8Å; M46-M276 HydrophobicContact SD-SD 4.46Å; M46-F299 HydrophobicContact CE-CE1 4.4Å; M46-F299 HydrophobicContact CE-CZ 4.36Å; M46-F299 HydrophobicContact SD-CE1 3.92Å; M46-F299 HydrophobicContact SD-CZ 3.61Å; M46-N303 VanDerWaalsContact O-O 3.13Å; M46-P344 HydrophobicContact CE-CG 3.93Å; M46-P344 HydrophobicContact CG-CG 3.98Å; M46-P344 HydrophobicContact SD-CG 3.71Å
47G98.1Very high97.9Very high0 Ų017.4 Ų17.40%010%0.098CC..  trans-79.3159.117600000113.3G49 D50 S315G47-G49 PolarHBondContact O-N 3.34Å; G47-G49 VanDerWaalsContact O-N 3.17Å; G47-D50 VanDerWaalsContact CA-OD2 3.3Å; G47-D50 WeakPolarHBondContact CA-OD2 3.41Å; G47-D50 PolarHBondContact N-OD2 3.2Å; G47-D50 WeakPolarHBondContact O-CB 3.34Å; G47-D50 PolarHBondContact O-N 2.88Å; G47-S315 CarbonylContact C-O 3.58Å; G47-S315 VanDerWaalsContact CA-O 3.31Å; G47-S315 WeakPolarHBondContact CA-O 3.43Å
48W98.6Very high97.6Very high22 Ų2218.2 Ų18.28%0.08310%0.104CC..G310 helixtrans-55.6-34.4178.3-172.497.5000113.1D50 N54 W55 V75 F319 R342W48-D50 VanDerWaalsContact C-N 3.28Å; W48-D50 PolarHBondContact O-N 3.27Å; W48-N54 HydrophobicContact CD2-CB 3.88Å; W48-N54 HydrophobicContact CE3-CB 3.8Å; W48-N54 HydrophobicContact CH2-CB 3.66Å; W48-N54 WeakPolarHBondContact CH2-O 3.41Å; W48-N54 HydrophobicContact CZ2-CB 3.74Å; W48-N54 HydrophobicContact CZ3-CB 3.69Å; W48-N54 WeakPolarHBondContact CZ3-O 3.42Å; W48-N54 PolarHBondContact NE1-ND2 2.98Å; W48-N54 VanDerWaalsContact O-CB 3.29Å; W48-N54 WeakPolarHBondContact O-CB 3.15Å; W48-N54 PolarHBondContact O-ND2 3.31Å; W48-N54 VanDerWaalsContact O-ND2 3.17Å; W48-W55 HydrophobicContact CZ3-CB 4.45Å; W48-W55 HydrophobicContact CZ3-CE3 4.33Å; W48-V75 HydrophobicContact CZ2-CB 4.31Å; W48-V75 HydrophobicContact CZ2-CG1 4.22Å; W48-V75 PolarHBondContact NE1-O 3.09Å; W48-F319 HydrophobicContact CB-CD2 4.11Å; W48-F319 HydrophobicContact CB-CE2 4.24Å; W48-F319 HydrophobicContact CD2-CD2 4.12Å; W48-F319 AromaticContact CD2-CE2 3.48Å; W48-F319 HydrophobicContact CD2-CE2 3.48Å; W48-F319 VanDerWaalsContact CD2-CE2 3.48Å; W48-F319 AromaticContact CE2-CE2 3.73Å; W48-F319 HydrophobicContact CE3-CD2 4.27Å; W48-F319 AromaticContact CE3-CE2 3.81Å; W48-F319 HydrophobicContact CE3-CE2 3.81Å; W48-F319 HydrophobicContact CG-CD2 4.05Å; W48-F319 AromaticContact CG-CE2 3.67Å; W48-F319 HydrophobicContact CG-CE2 3.67Å; W48-F319 HydrophobicContact CZ2-CE2 4.28Å; W48-F319 HydrophobicContact CZ3-CE2 4.34Å; W48-F319 AromaticContact NE1-CE2 3.99Å; W48-R342 HydrophobicContact CG-CG 4.44Å
49G98.1Very high97.4Very high0 Ų025.6 Ų25.60%014%0.136CC..G310 helixtrans-79.9-2.4179.900000114.8G47 L51 W55 T58 S315G47-G49 PolarHBondContact O-N 3.34Å; G47-G49 VanDerWaalsContact O-N 3.17Å; G49-L51 VanDerWaalsContact C-N 3.32Å; G49-W55 WeakPolarHBondContact O-CB 3.33Å; G49-T58 PolarHBondContact O-OG1 2.71Å; G49-S315 WeakPolarHBondContact CA-O 3.18Å; G49-S315 PolarHBondContact N-O 3.3Å
50D98.1Very high97.2Very high6 Ų627.6 Ų27.63%0.03215%0.146CC..G310 helixtrans-86.4-4.5177.8-61.8-46.3000112.9M46 G47 W48 T58 T61 Y269 L273 G314 S315M46-D50 HydrophobicContact CE-CB 3.75Å; M46-D50 WeakPolarHBondContact CE-O 3.32Å; M46-D50 HydrophobicContact CG-CB 3.78Å; G47-D50 VanDerWaalsContact CA-OD2 3.3Å; G47-D50 WeakPolarHBondContact CA-OD2 3.41Å; G47-D50 PolarHBondContact N-OD2 3.2Å; G47-D50 WeakPolarHBondContact O-CB 3.34Å; G47-D50 PolarHBondContact O-N 2.88Å; W48-D50 VanDerWaalsContact C-N 3.28Å; W48-D50 PolarHBondContact O-N 3.27Å; D50-T58 VanDerWaalsContact O-CG2 3.29Å; D50-T58 WeakPolarHBondContact O-CG2 3.47Å; D50-T61 VanDerWaalsContact O-CG2 3.24Å; D50-T61 WeakPolarHBondContact O-CG2 3.46Å; D50-Y269 HydrophobicContact CB-CE1 4.31Å; D50-Y269 VanDerWaalsContact OD1-CE1 3.3Å; D50-Y269 WeakPolarHBondContact OD1-CE1 3.23Å; D50-Y269 PolarHBondContact OD2-OH 3.34Å; D50-L273 HydrophobicContact CB-CD2 4.33Å; D50-L273 WeakPolarHBondContact O-CD2 3.49Å; D50-G314 WeakPolarHBondContact OD1-CA 3.38Å; D50-G314 WeakPolarHBondContact OD2-CA 3.11Å; D50-S315 WeakPolarHBondContact OD1-CB 3.29Å; D50-S315 PolarHBondContact OD1-N 2.85Å; D50-S315 PolarHBondContact OD2-N 2.78Å
51L98.4Very high97.1Very high0 Ų027.4 Ų27.40%015%0.145CC..SBendtrans-96.9121.9171.6176.561.8000109.8M46 G49 A53 N54 W55 L64 P344 L346M46-L51 HydrophobicContact CE-CB 4.15Å; G49-L51 VanDerWaalsContact C-N 3.32Å; L51-A53 VanDerWaalsContact C-N 3.27Å; L51-A53 HydrophobicContact CD1-CB 4.38Å; L51-A53 HydrophobicContact CD2-CB 4.3Å; L51-A53 HydrophobicContact CG-CB 4.05Å; L51-A53 PolarHBondContact O-N 3.16Å; L51-N54 HydrophobicContact CB-CB 4.13Å; L51-N54 HydrophobicContact CG-CB 4.43Å; L51-N54 WeakPolarHBondContact O-CA 3.33Å; L51-N54 WeakPolarHBondContact O-CB 3.29Å; L51-N54 PolarHBondContact O-N 3.29Å; L51-W55 PolarHBondContact O-N 3.04Å; L51-L64 HydrophobicContact CD1-CB 3.59Å; L51-L64 HydrophobicContact CD1-CD1 4.32Å; L51-P344 HydrophobicContact CB-CB 3.83Å; L51-P344 HydrophobicContact CD2-CB 3.86Å; L51-P344 HydrophobicContact CG-CB 4.48Å; L51-L346 HydrophobicContact CD1-CD1 4.41Å; L51-L346 HydrophobicContact CD2-CD1 4.26Å; L51-L346 HydrophobicContact CD2-CD2 3.98Å; L51-L346 HydrophobicContact CD2-CG 4.16Å
52G97.8Very high97.1Very high13 Ų1330.6 Ų30.613%0.13417%0.172CC..THydrogen-bonded Turntrans-56.9-38.2178.900000113.5N54 W55 T58 T61 D65G52-N54 PolarHBondContact O-N 3Å; G52-W55 CarbonylContact O-C 3.58Å; G52-W55 PolarHBondContact O-N 2.94Å; G52-T58 VanDerWaalsContact CA-O 3.29Å; G52-T58 WeakPolarHBondContact CA-O 3.19Å; G52-T61 PolarHBondContact N-OG1 3.01Å; G52-D65 WeakPolarHBondContact CA-OD1 3.3Å; G52-D65 PolarHBondContact N-OD1 3.31Å
53A97.5Very high97.1Very high32 Ų3233.1 Ų33.126%0.26419%0.185SC..THydrogen-bonded Turntrans-63.3-21173.400000114L51 D65 A68 R73L51-A53 VanDerWaalsContact C-N 3.27Å; L51-A53 HydrophobicContact CD1-CB 4.38Å; L51-A53 HydrophobicContact CD2-CB 4.3Å; L51-A53 HydrophobicContact CG-CB 4.05Å; L51-A53 PolarHBondContact O-N 3.16Å; A53-D65 PolarHBondContact N-OD1 2.9Å; A53-A68 HydrophobicContact CB-CB 3.8Å; A53-R73 PolarHBondContact O-NE 2.95Å; A53-R73 PolarHBondContact O-NH1 3.01Å
54N97.7Very high97.1Very high16 Ų1633.1 Ų33.19%0.08619%0.185CC..THydrogen-bonded Turntrans-92.8-38.1174.6-79.2-5.5000112.7W48 L51 G52 R73W48-N54 HydrophobicContact CD2-CB 3.88Å; W48-N54 HydrophobicContact CE3-CB 3.8Å; W48-N54 HydrophobicContact CH2-CB 3.66Å; W48-N54 WeakPolarHBondContact CH2-O 3.41Å; W48-N54 HydrophobicContact CZ2-CB 3.74Å; W48-N54 HydrophobicContact CZ3-CB 3.69Å; W48-N54 WeakPolarHBondContact CZ3-O 3.42Å; W48-N54 PolarHBondContact NE1-ND2 2.98Å; W48-N54 VanDerWaalsContact O-CB 3.29Å; W48-N54 WeakPolarHBondContact O-CB 3.15Å; W48-N54 PolarHBondContact O-ND2 3.31Å; W48-N54 VanDerWaalsContact O-ND2 3.17Å; L51-N54 HydrophobicContact CB-CB 4.13Å; L51-N54 HydrophobicContact CG-CB 4.43Å; L51-N54 WeakPolarHBondContact O-CA 3.33Å; L51-N54 WeakPolarHBondContact O-CB 3.29Å; L51-N54 PolarHBondContact O-N 3.29Å; G52-N54 PolarHBondContact O-N 3Å; N54-R73 VanDerWaalsContact OD1-CD 3.3Å; N54-R73 WeakPolarHBondContact OD1-CD 3.47Å; N54-R73 PolarHBondContact OD1-NH1 3.39Å
55W96.8Very high97.1Very high77 Ų7735.4 Ų35.429%0.29220%0.197SC..  trans-137.5116.8-169.4-167.5-118.8000111.1W48 G49 L51 G52 E57 T58 A318W48-W55 HydrophobicContact CZ3-CB 4.45Å; W48-W55 HydrophobicContact CZ3-CE3 4.33Å; G49-W55 WeakPolarHBondContact O-CB 3.33Å; L51-W55 PolarHBondContact O-N 3.04Å; G52-W55 CarbonylContact O-C 3.58Å; G52-W55 PolarHBondContact O-N 2.94Å; W55-E57 VanDerWaalsContact CZ2-CD 3.49Å; W55-E57 HydrophobicContact CZ2-CG 4.44Å; W55-E57 WeakPolarHBondContact CZ2-OE2 3.38Å; W55-E57 PolarHBondContact NE1-OE2 3.28Å; W55-E57 VanDerWaalsContact NE1-OE2 3.09Å; W55-E57 PolarHBondContact O-N 3.13Å; W55-E57 VanDerWaalsContact O-N 3.12Å; W55-T58 PolarHBondContact O-N 3.09Å; W55-A318 HydrophobicContact CZ3-CB 4.22Å
56A94.2Very high97.1Very high67 Ų6739.9 Ų39.955%0.55422%0.217SC*.THydrogen-bonded Turntrans-65.1-22.4-168.100000113.4T58 K59A56-T58 PolarHBondContact O-N 3.24Å; A56-K59 WeakPolarHBondContact O-CE 3.21Å; A56-K59 PolarHBondContact O-NZ 3.24Å
57E93.4Very high97.2Very high123 Ų12340 Ų4058%0.57522%0.217SC*.THydrogen-bonded Turntrans-72.6-18.7178.3-66.275176.300111.9W55W55-E57 VanDerWaalsContact CZ2-CD 3.49Å; W55-E57 HydrophobicContact CZ2-CG 4.44Å; W55-E57 WeakPolarHBondContact CZ2-OE2 3.38Å; W55-E57 PolarHBondContact NE1-OE2 3.28Å; W55-E57 VanDerWaalsContact NE1-OE2 3.09Å; W55-E57 PolarHBondContact O-N 3.13Å; W55-E57 VanDerWaalsContact O-N 3.12Å
58T94.1Very high97.2Very high18 Ų1840.4 Ų40.411%0.1122%0.221CC..  trans-92.6126178.4-58.90000110.4G49 D50 G52 W55 A56 L273G49-T58 PolarHBondContact O-OG1 2.71Å; D50-T58 VanDerWaalsContact O-CG2 3.29Å; D50-T58 WeakPolarHBondContact O-CG2 3.47Å; G52-T58 VanDerWaalsContact CA-O 3.29Å; G52-T58 WeakPolarHBondContact CA-O 3.19Å; W55-T58 PolarHBondContact O-N 3.09Å; A56-T58 PolarHBondContact O-N 3.24Å; T58-L273 HydrophobicContact CG2-CD2 3.93Å
59K93.4Very high97.2Very high155 Ų15542.1 Ų42.167%0.67424%0.236SC*.  trans-124.85.8-175.3-59.5-58.8-177.5-154.80113.9A56A56-K59 WeakPolarHBondContact O-CE 3.21Å; A56-K59 PolarHBondContact O-NZ 3.24Å
60D95.2Very high97.2Very high42 Ų4244.9 Ų44.923%0.22525%0.249CC..SBendtrans-99.96.4-166.5-72.1-42.4000113.6G270 L273 R274D60-G270 VanDerWaalsContact OD2-CA 3.32Å; D60-G270 WeakPolarHBondContact OD2-CA 3.41Å; D60-L273 HydrophobicContact CB-CB 4.23Å; D60-L273 HydrophobicContact CB-CD2 3.87Å; D60-L273 HydrophobicContact CB-CG 4.09Å; D60-R274 HydrophobicContact CB-CG 3.72Å; D60-R274 WeakPolarHBondContact O-CA 3.45Å; D60-R274 WeakPolarHBondContact O-CG 3.45Å; D60-R274 WeakPolarHBondContact OD1-CD 3.23Å; D60-R274 IonicContact OD1-CZ 3.59Å; D60-R274 IonicContact OD1-NE 3Å; D60-R274 IonicContact OD1-NH1 3.75Å; D60-R274 PolarHBondContact OD1-NH1 3.3Å; D60-R274 IonicContact OD2-NH1 3.32Å
61T97.5Very high97.2Very high0 Ų044.6 Ų44.60%025%0.247CC..  trans-121.448.1-172.656.40000113.3D50 G52 N63 L64 D65 L273 D277D50-T61 VanDerWaalsContact O-CG2 3.24Å; D50-T61 WeakPolarHBondContact O-CG2 3.46Å; G52-T61 PolarHBondContact N-OG1 3.01Å; T61-N63 VanDerWaalsContact C-N 3.32Å; T61-N63 PolarHBondContact O-N 2.85Å; T61-L64 HydrophobicContact CG2-CD1 4.15Å; T61-L64 PolarHBondContact O-N 2.77Å; T61-D65 WeakPolarHBondContact O-CB 3.28Å; T61-D65 PolarHBondContact O-N 2.71Å; T61-D65 PolarHBondContact OG1-OD1 3.38Å; T61-D65 VanDerWaalsContact OG1-OD1 3.08Å; T61-L273 HydrophobicContact CG2-CD1 3.76Å; T61-L273 HydrophobicContact CG2-CD2 3.85Å; T61-L273 HydrophobicContact CG2-CG 3.65Å; T61-D277 VanDerWaalsContact C-CG 3.43Å; T61-D277 VanDerWaalsContact CA-CG 3.45Å; T61-D277 VanDerWaalsContact CA-OD1 3.29Å; T61-D277 WeakPolarHBondContact CA-OD1 3.49Å
62A98.1Very high97.2Very high67 Ų6744.7 Ų44.755%0.55425%0.248SC*.Hα-helixtrans-60.2-36.7-171.900000114K66 D277A62-K66 WeakPolarHBondContact O-CB 3.14Å; A62-K66 PolarHBondContact O-N 3.4Å; A62-D277 PolarHBondContact N-OD2 3.19Å; A62-D277 VanDerWaalsContact N-OD2 3.12Å
63N98.8Very high97.2Very high52 Ų5246.2 Ų46.228%0.27825%0.249SC..Hα-helixtrans-74.1-40.7179.6-64.9-76.9000111.9T61 K66 M67 D277T61-N63 VanDerWaalsContact C-N 3.32Å; T61-N63 PolarHBondContact O-N 2.85Å; N63-K66 WeakPolarHBondContact O-CB 3.44Å; N63-K66 PolarHBondContact O-N 2.94Å; N63-M67 PolarHBondContact O-N 3.32Å; N63-D277 WeakPolarHBondContact CB-OD1 3.42Å; N63-D277 WeakPolarHBondContact CB-OD2 3.27Å; N63-D277 PolarHBondContact N-OD1 2.96Å; N63-D277 VanDerWaalsContact N-OD1 3.09Å; N63-D277 PolarHBondContact N-OD2 2.76Å; N63-D277 PolarHBondContact ND2-O 3.44Å; N63-D277 PolarHBondContact ND2-OD2 3.12Å
64L98.8Very high97.3Very high0 Ų044.7 Ų44.70%024%0.237CC..Hα-helixtrans-66.6-39.6173.4-70.5167.7000111.6M46 L51 T61 K66 M67 A68 M276 D277 V280 F299 L346M46-L64 HydrophobicContact CE-CD1 4.44Å; L51-L64 HydrophobicContact CD1-CB 3.59Å; L51-L64 HydrophobicContact CD1-CD1 4.32Å; T61-L64 HydrophobicContact CG2-CD1 4.15Å; T61-L64 PolarHBondContact O-N 2.77Å; L64-K66 VanDerWaalsContact C-N 3.29Å; L64-K66 PolarHBondContact O-N 3.47Å; L64-M67 CarbonylContact O-C 3.58Å; L64-M67 WeakPolarHBondContact O-CB 3.42Å; L64-M67 PolarHBondContact O-N 2.91Å; L64-M67 VanDerWaalsContact O-N 3.16Å; L64-A68 WeakPolarHBondContact O-CB 3.31Å; L64-A68 PolarHBondContact O-N 2.78Å; L64-M276 HydrophobicContact CD1-CE 3.9Å; L64-D277 WeakPolarHBondContact CG-OD1 3.41Å; L64-D277 PolarHBondContact N-OD1 3.23Å; L64-V280 HydrophobicContact CD2-CG1 3.81Å; L64-V280 HydrophobicContact CG-CG1 4.46Å; L64-F299 HydrophobicContact CD1-CE1 3.98Å; L64-F299 HydrophobicContact CD1-CE2 4.14Å; L64-F299 HydrophobicContact CD1-CZ 3.68Å; L64-F299 HydrophobicContact CD2-CB 4.36Å; L64-F299 HydrophobicContact CD2-CD1 3.74Å; L64-F299 HydrophobicContact CD2-CD2 3.64Å; L64-F299 HydrophobicContact CD2-CE1 3.87Å; L64-F299 HydrophobicContact CD2-CE2 3.77Å; L64-F299 HydrophobicContact CD2-CG 3.63Å; L64-F299 HydrophobicContact CD2-CZ 3.88Å; L64-F299 HydrophobicContact CG-CZ 4.47Å; L64-L346 HydrophobicContact CB-CD1 4.11Å; L64-L346 HydrophobicContact CD2-CD1 3.99Å; L64-L346 VanDerWaalsContact O-CD1 3.29Å; L64-L346 WeakPolarHBondContact O-CD1 3.33Å
65D98.8Very high97.2Very high48 Ų4845.4 Ų45.426%0.25724%0.242SC..Hα-helixtrans-62.7-39.8175.2-68.1-7.7000110.8G52 A53 T61 A68 S69G52-D65 WeakPolarHBondContact CA-OD1 3.3Å; G52-D65 PolarHBondContact N-OD1 3.31Å; A53-D65 PolarHBondContact N-OD1 2.9Å; T61-D65 WeakPolarHBondContact O-CB 3.28Å; T61-D65 PolarHBondContact O-N 2.71Å; T61-D65 PolarHBondContact OG1-OD1 3.38Å; T61-D65 VanDerWaalsContact OG1-OD1 3.08Å; D65-A68 WeakPolarHBondContact O-CB 3.22Å; D65-A68 PolarHBondContact O-N 3.24Å; D65-S69 PolarHBondContact O-N 3.38Å
66K98.6Very high97.3Very high100 Ų10042.8 Ų42.844%0.43523%0.234SC..Hα-helixtrans-62.4-47.5171-177.2179.3173.6-172.10111.5A62 N63 L64 A68 S69 E70A62-K66 WeakPolarHBondContact O-CB 3.14Å; A62-K66 PolarHBondContact O-N 3.4Å; N63-K66 WeakPolarHBondContact O-CB 3.44Å; N63-K66 PolarHBondContact O-N 2.94Å; L64-K66 VanDerWaalsContact C-N 3.29Å; L64-K66 PolarHBondContact O-N 3.47Å; K66-A68 VanDerWaalsContact C-N 3.26Å; K66-A68 PolarHBondContact O-N 3.41Å; K66-S69 PolarHBondContact O-N 3.24Å; K66-S69 VanDerWaalsContact O-N 3.09Å; K66-S69 PolarHBondContact O-OG 3.49Å; K66-E70 WeakPolarHBondContact CE-OE1 3.48Å; K66-E70 HydrophobicContact CG-CG 4.35Å; K66-E70 IonicContact NZ-OE1 3.16Å; K66-E70 WeakPolarHBondContact O-CB 3.48Å; K66-E70 WeakPolarHBondContact O-CG 3.23Å; K66-E70 PolarHBondContact O-N 2.99Å
67M98.6Very high97.5Very high2 Ų239.6 Ų39.61%0.0121%0.207CC..Hα-helixtrans-57.9-38.5175.7-176.9-177.8173.400112N63 L64 E70 G71 K284 L297 F299 L346 Y348N63-M67 PolarHBondContact O-N 3.32Å; L64-M67 CarbonylContact O-C 3.58Å; L64-M67 WeakPolarHBondContact O-CB 3.42Å; L64-M67 PolarHBondContact O-N 2.91Å; L64-M67 VanDerWaalsContact O-N 3.16Å; M67-E70 PolarHBondContact O-N 2.65Å; M67-G71 PolarHBondContact O-N 2.93Å; M67-K284 HydrophobicContact CB-CD 4.14Å; M67-K284 HydrophobicContact CG-CD 4.22Å; M67-L297 HydrophobicContact CE-CB 3.7Å; M67-F299 HydrophobicContact CE-CB 4.25Å; M67-F299 HydrophobicContact SD-CB 4.4Å; M67-L346 HydrophobicContact CB-CD1 4.3Å; M67-L346 HydrophobicContact CE-CB 4.14Å; M67-L346 HydrophobicContact CG-CD1 4.37Å; M67-L346 HydrophobicContact SD-CB 4.33Å; M67-L346 HydrophobicContact SD-CD1 4.31Å; M67-Y348 HydrophobicContact CG-CG 4.39Å
68A98.5Very high97.8Very high9 Ų933.8 Ų33.87%0.07418%0.18CC..Hα-helixtrans-63.6-43.4174.300000111.9A53 L64 D65 K66 E70 G71 R73 L346A53-A68 HydrophobicContact CB-CB 3.8Å; L64-A68 WeakPolarHBondContact O-CB 3.31Å; L64-A68 PolarHBondContact O-N 2.78Å; D65-A68 WeakPolarHBondContact O-CB 3.22Å; D65-A68 PolarHBondContact O-N 3.24Å; K66-A68 VanDerWaalsContact C-N 3.26Å; K66-A68 PolarHBondContact O-N 3.41Å; A68-E70 VanDerWaalsContact C-N 3.29Å; A68-E70 PolarHBondContact O-N 2.81Å; A68-G71 CarbonylContact O-C 3.32Å; A68-G71 PolarHBondContact O-N 3.41Å; A68-R73 HydrophobicContact CB-CB 4.43Å; A68-L346 HydrophobicContact CB-CD1 4.19Å; A68-L346 HydrophobicContact CB-CD2 3.53Å
69S98.3Very high98Very high58 Ų5833 Ų3341%0.40618%0.175SC..Hα-helixtrans-68.6-27.3176.676.20000113.3D65 K66 V355 N356D65-S69 PolarHBondContact O-N 3.38Å; K66-S69 PolarHBondContact O-N 3.24Å; K66-S69 VanDerWaalsContact O-N 3.09Å; K66-S69 PolarHBondContact O-OG 3.49Å; S69-V355 VanDerWaalsContact O-CG1 3.23Å; S69-V355 WeakPolarHBondContact O-CG1 3.32Å; S69-N356 WeakPolarHBondContact O-CA 3.27Å; S69-N356 WeakPolarHBondContact O-CB 3.38Å; S69-N356 PolarHBondContact O-N 3.17Å
70E98.3Very high98.2Very high57 Ų5725.7 Ų25.727%0.26614%0.144SC..THydrogen-bonded Turntrans-91.4-2.3179.7-68.617917000113.2K66 M67 A68 K284 Y348K66-E70 WeakPolarHBondContact CE-OE1 3.48Å; K66-E70 HydrophobicContact CG-CG 4.35Å; K66-E70 IonicContact NZ-OE1 3.16Å; K66-E70 WeakPolarHBondContact O-CB 3.48Å; K66-E70 WeakPolarHBondContact O-CG 3.23Å; K66-E70 PolarHBondContact O-N 2.99Å; M67-E70 PolarHBondContact O-N 2.65Å; A68-E70 VanDerWaalsContact C-N 3.29Å; A68-E70 PolarHBondContact O-N 2.81Å; E70-K284 VanDerWaalsContact OE2-CE 3.27Å; E70-K284 WeakPolarHBondContact OE2-CE 3.34Å; E70-K284 IonicContact OE2-NZ 3.98Å; E70-K284 PolarHBondContact OE2-NZ 3.47Å; E70-Y348 HydrophobicContact CB-CD2 4.05Å; E70-Y348 HydrophobicContact CB-CE2 3.84Å
71G98.3Very high98.3Very high0 Ų024 Ų240%014%0.135CC..SBendtrans-150.4-142.7-175.300000112.6M67 A68 A347 P354 V355 N356 V357M67-G71 PolarHBondContact O-N 2.93Å; A68-G71 CarbonylContact O-C 3.32Å; A68-G71 PolarHBondContact O-N 3.41Å; G71-A347 WeakPolarHBondContact CA-O 3.19Å; G71-P354 CarbonylContact C-O 3.51Å; G71-P354 VanDerWaalsContact O-O 3.08Å; G71-V355 CarbonylContact O-C 3.52Å; G71-N356 PolarHBondContact O-N 3.38Å; G71-V357 PolarHBondContact O-N 2.75Å; G71-V357 VanDerWaalsContact O-N 3.17Å
72M98.5Very high98.4Very high3 Ų324 Ų242%0.01514%0.136CC..EExtended strand (participates in β ladder)trans-115.1134.8-179.2-175.9178.3-6200110.9F74 L346 A347 V353 P354 V357 V394M72-F74 HydrophobicContact CG-CE1 4.2Å; M72-F74 HydrophobicContact CG-CE2 4.4Å; M72-F74 HydrophobicContact CG-CZ 4.01Å; M72-F74 HydrophobicContact SD-CD1 4.47Å; M72-F74 HydrophobicContact SD-CE1 3.54Å; M72-F74 VanDerWaalsContact SD-CE1 3.54Å; M72-F74 HydrophobicContact SD-CE2 4.46Å; M72-F74 HydrophobicContact SD-CZ 3.53Å; M72-F74 VanDerWaalsContact SD-CZ 3.53Å; M72-L346 CarbonylContact O-C 3.36Å; M72-L346 WeakPolarHBondContact O-CA 3.46Å; M72-A347 HydrophobicContact CB-CB 4.39Å; M72-A347 PolarHBondContact N-O 2.98Å; M72-A347 PolarHBondContact O-N 3.1Å; M72-V353 HydrophobicContact CB-CG1 3.62Å; M72-P354 HydrophobicContact CE-CB 4.48Å; M72-P354 HydrophobicContact CE-CG 4.13Å; M72-V357 CarbonylContact C-O 3.59Å; M72-V357 VanDerWaalsContact CA-O 3.29Å; M72-V357 WeakPolarHBondContact CA-O 3.47Å; M72-V357 HydrophobicContact CE-CB 4.34Å; M72-V357 HydrophobicContact CE-CG1 3.97Å; M72-V357 HydrophobicContact CG-CB 4.39Å; M72-V357 HydrophobicContact CG-CG1 4.27Å; M72-V394 WeakPolarHBondContact CE-O 3.38Å
73R98.4Very high98.3Very high44 Ų4421.1 Ų21.117%0.16611%0.111CC..EExtended strand (participates in β ladder)trans-109134.2173.3179.217971105.7-3.2110.2A53 N54 A68 V75 L346 V357 T358 S359A53-R73 PolarHBondContact O-NE 2.95Å; A53-R73 PolarHBondContact O-NH1 3.01Å; N54-R73 VanDerWaalsContact OD1-CD 3.3Å; N54-R73 WeakPolarHBondContact OD1-CD 3.47Å; N54-R73 PolarHBondContact OD1-NH1 3.39Å; A68-R73 HydrophobicContact CB-CB 4.43Å; R73-V75 VanDerWaalsContact NH1-CG1 3.26Å; R73-L346 HydrophobicContact CB-CD2 3.7Å; R73-L346 HydrophobicContact CG-CD2 3.72Å; R73-V357 PolarHBondContact N-O 3.38Å; R73-T358 PolarHBondContact NH2-OG1 2.91Å; R73-T358 CarbonylContact O-C 3.58Å; R73-T358 WeakPolarHBondContact O-CA 3.24Å; R73-S359 PolarHBondContact O-N 3.35Å
74F98.5Very high98.3Very high0 Ų018.6 Ų18.60%010%0.098CC..EExtended strand (participates in β ladder)trans-103.4128.1175.2-56.4-84000110.2M72 F77 A345 A347 L363 V394 L395M72-F74 HydrophobicContact CG-CE1 4.2Å; M72-F74 HydrophobicContact CG-CE2 4.4Å; M72-F74 HydrophobicContact CG-CZ 4.01Å; M72-F74 HydrophobicContact SD-CD1 4.47Å; M72-F74 HydrophobicContact SD-CE1 3.54Å; M72-F74 VanDerWaalsContact SD-CE1 3.54Å; M72-F74 HydrophobicContact SD-CE2 4.46Å; M72-F74 HydrophobicContact SD-CZ 3.53Å; M72-F74 VanDerWaalsContact SD-CZ 3.53Å; F74-F77 HydrophobicContact CB-CB 3.93Å; F74-F77 HydrophobicContact CB-CD2 4.38Å; F74-F77 HydrophobicContact CG-CD2 4.47Å; F74-A345 HydrophobicContact CB-CB 4.19Å; F74-A345 HydrophobicContact CD2-CB 4.11Å; F74-A345 PolarHBondContact N-O 2.87Å; F74-A347 HydrophobicContact CE2-CB 3.71Å; F74-A347 HydrophobicContact CZ-CB 4.2Å; F74-L363 HydrophobicContact CD1-CD1 3.53Å; F74-L363 HydrophobicContact CE1-CD1 3.42Å; F74-L363 VanDerWaalsContact CE1-CD1 3.42Å; F74-L363 HydrophobicContact CG-CD1 4.3Å; F74-L363 HydrophobicContact CZ-CD1 4.11Å; F74-V394 HydrophobicContact CE1-CG1 4.06Å; F74-L395 HydrophobicContact CE2-CD2 4.3Å; F74-L395 HydrophobicContact CZ-CD2 3.82Å
75V97.3Very high98.3Very high31 Ų3118.6 Ų18.619%0.18810%0.098CC..SBendtrans-97.3-16178.2-66.30000113.4W48 R73 T358 S359 T360W48-V75 HydrophobicContact CZ2-CB 4.31Å; W48-V75 HydrophobicContact CZ2-CG1 4.22Å; W48-V75 PolarHBondContact NE1-O 3.09Å; R73-V75 VanDerWaalsContact NH1-CG1 3.26Å; V75-T358 HydrophobicContact CG1-CG2 3.68Å; V75-T358 HydrophobicContact CG2-CG2 4.24Å; V75-S359 WeakPolarHBondContact CG2-O 3.5Å; V75-S359 PolarHBondContact N-O 2.61Å; V75-S359 VanDerWaalsContact N-O 3.12Å; V75-T360 HydrophobicContact CG2-CG2 3.88Å
76D98Very high98.3Very high23 Ų2316.6 Ų16.612%0.1239%0.087CC..SBendtrans-120.958.4179.9-158.1-12.5000110.5H78 R342 A361 L362 L363 R424D76-H78 IonicContact OD1-CD2 2.71Å; D76-H78 PolarHBondContact OD1-CD2 3.46Å; D76-H78 IonicContact OD1-CE1 3.68Å; D76-H78 IonicContact OD1-NE2 3.44Å; D76-H78 PolarHBondContact OD1-NE2 3.48Å; D76-R342 IonicContact OD1-CZ 3.39Å; D76-R342 IonicContact OD1-NE 2.91Å; D76-R342 IonicContact OD1-NH2 3.9Å; D76-R342 PolarHBondContact OD1-NH2 3.3Å; D76-R342 IonicContact OD2-NH2 3.19Å; D76-R342 PolarHBondContact OD2-NH2 2.99Å; D76-A361 VanDerWaalsContact O-O 3.09Å; D76-L362 WeakPolarHBondContact OD1-CD1 3.4Å; D76-L363 PolarHBondContact O-N 2.91Å; D76-R424 IonicContact OD2-NH2 2.73Å
77F98.8Very high98.3Very high0 Ų011.8 Ų11.80%07%0.066CC..EExtended strand (participates in β ladder)trans-115.7133-178.4-166.7-84.1000111.5F74 W298 T300 R342 V343 A345 L363 S364 V365F74-F77 HydrophobicContact CB-CB 3.93Å; F74-F77 HydrophobicContact CB-CD2 4.38Å; F74-F77 HydrophobicContact CG-CD2 4.47Å; F77-W298 AromaticContact CE2-CZ2 3.81Å; F77-W298 HydrophobicContact CE2-CZ2 3.81Å; F77-W298 HydrophobicContact CZ-CZ2 4.3Å; F77-T300 HydrophobicContact CE1-CG2 4.31Å; F77-T300 WeakPolarHBondContact CE1-OG1 3.49Å; F77-R342 WeakPolarHBondContact O-CA 3.46Å; F77-V343 HydrophobicContact CD1-CG2 3.82Å; F77-V343 HydrophobicContact CE1-CG2 4.35Å; F77-V343 PolarHBondContact O-N 3.07Å; F77-A345 HydrophobicContact CB-CB 3.64Å; F77-A345 HydrophobicContact CD1-CB 3.52Å; F77-A345 HydrophobicContact CD2-CB 3.76Å; F77-A345 HydrophobicContact CE1-CB 4.06Å; F77-A345 HydrophobicContact CE2-CB 4.32Å; F77-A345 HydrophobicContact CG-CB 3.34Å; F77-A345 HydrophobicContact CZ-CB 4.45Å; F77-L363 WeakPolarHBondContact CA-O 3.09Å; F77-L363 HydrophobicContact CD2-CB 3.61Å; F77-L363 HydrophobicContact CD2-CD1 4.41Å; F77-L363 HydrophobicContact CE2-CB 3.92Å; F77-S364 VanDerWaalsContact CZ-C 3.44Å; F77-V365 HydrophobicContact CE1-CB 4.45Å; F77-V365 HydrophobicContact CE1-CG2 3.61Å; F77-V365 HydrophobicContact CZ-CG2 4.2Å
78H98.8Very high98.3Very high1 Ų111.7 Ų11.71%0.0057%0.066CC..EExtended strand (participates in β ladder)trans-126130.5-167.5-68.2-94.1000113.6D76 E338 H341 R342 L363 S364 V365 L406 H408D76-H78 IonicContact OD1-CD2 2.71Å; D76-H78 PolarHBondContact OD1-CD2 3.46Å; D76-H78 IonicContact OD1-CE1 3.68Å; D76-H78 IonicContact OD1-NE2 3.44Å; D76-H78 PolarHBondContact OD1-NE2 3.48Å; H78-E338 IonicContact CE1-OE1 3.65Å; H78-E338 IonicContact CE1-OE2 2.61Å; H78-H341 CarbonylContact C-O 3.53Å; H78-H341 WeakPolarHBondContact CA-O 3.4Å; H78-H341 AromaticContact CE1-CE1 3.59Å; H78-H341 AromaticContact CE1-ND1 3.66Å; H78-H341 AromaticContact CG-ND1 3.82Å; H78-H341 AromaticContact ND1-CE1 3.16Å; H78-H341 PolarHBondContact ND1-CE1 2.99Å; H78-H341 AromaticContact ND1-ND1 2.8Å; H78-H341 PolarHBondContact ND1-ND1 3.48Å; H78-R342 PolarHBondContact CE1-NE 3.32Å; H78-R342 VanDerWaalsContact CE1-NE 3.32Å; H78-R342 PolarHBondContact NE2-NE 2.81Å; H78-R342 PolarHBondContact NE2-NH2 3.34Å; H78-L363 PolarHBondContact N-O 2.79Å; H78-S364 CarbonylContact O-C 3.49Å; H78-S364 WeakPolarHBondContact O-CA 3.38Å; H78-S364 WeakPolarHBondContact O-CB 3.49Å; H78-S364 PolarHBondContact O-OG 3.48Å; H78-V365 PolarHBondContact O-N 2.93Å; H78-L406 HydrophobicContact CB-CD1 4Å; H78-H408 AromaticContact ND1-CE1 3.79Å
79A98.7Very high98.3Very high1 Ų111.3 Ų11.31%0.0086%0.062CC..  trans-57.8148.616000000110.9A81 D302 H341 V343A79-A81 VanDerWaalsContact C-N 3.28Å; A79-A81 WeakPolarHBondContact CB-O 3.34Å; A79-A81 PolarHBondContact O-N 2.84Å; A79-D302 WeakPolarHBondContact CB-O 3.41Å; A79-H341 HydrophobicContact CB-CB 4.3Å; A79-H341 WeakPolarHBondContact CB-O 3.11Å; A79-H341 PolarHBondContact N-O 3.37Å; A79-V343 HydrophobicContact CB-CG1 4.18Å; A79-V343 HydrophobicContact CB-CG2 4.48Å
80A97.5Very high98.4Very high2 Ų28.6 Ų8.62%0.0174%0.043CC..SBendtrans-75.4-20.4-179.600000112.9S90 L366 P409A80-S90 WeakPolarHBondContact CB-OG 3.44Å; A80-L366 HydrophobicContact CB-CD1 4.31Å; A80-L366 HydrophobicContact CB-CD2 4.05Å; A80-L366 HydrophobicContact CB-CG 3.84Å; A80-P409 WeakPolarHBondContact O-CD 3.34Å; A80-P409 WeakPolarHBondContact O-CG 3.36Å
81A98.1Very high98.4Very high5 Ų55.9 Ų5.94%0.0413%0.031CC..SBendtrans-151.9161.7175.800000109.2A79 T83 P86A79-A81 VanDerWaalsContact C-N 3.28Å; A79-A81 WeakPolarHBondContact CB-O 3.34Å; A79-A81 PolarHBondContact O-N 2.84Å; A81-T83 VanDerWaalsContact C-N 3.26Å; A81-T83 PolarHBondContact O-N 3.5Å; A81-P86 HydrophobicContact CB-CB 3.64Å
82S98.1Very high98.4Very high2 Ų26 Ų61%0.0143%0.032CC..SBendtrans-94.530.9179.7-167.10000112.6K333 Q334 T335 G340 S411S82-K333 WeakPolarHBondContact O-CG 3.34Å; S82-K333 WeakPolarHBondContact OG-CA 3.27Å; S82-Q334 WeakPolarHBondContact O-CA 3.35Å; S82-Q334 PolarHBondContact O-N 3.03Å; S82-Q334 PolarHBondContact OG-N 3.39Å; S82-T335 WeakPolarHBondContact CB-O 3.47Å; S82-T335 PolarHBondContact OG-N 2.86Å; S82-T335 PolarHBondContact OG-O 2.77Å; S82-G340 WeakPolarHBondContact CB-O 3.18Å; S82-G340 WeakPolarHBondContact OG-CA 3.23Å; S82-G340 PolarHBondContact OG-O 2.73Å; S82-S411 PolarHBondContact N-OG 2.95Å
83T97.6Very high98.4Very high5 Ų55.9 Ų5.93%0.0313%0.031CC..SBendtrans-149.6155.7176.346.90000111.3A81 P86 S87 N303 Q334 S411A81-T83 VanDerWaalsContact C-N 3.26Å; A81-T83 PolarHBondContact O-N 3.5Å; T83-P86 WeakPolarHBondContact OG1-CD 3.33Å; T83-P86 WeakPolarHBondContact OG1-CG 3.41Å; T83-S87 VanDerWaalsContact O-CB 3.23Å; T83-S87 WeakPolarHBondContact O-CB 3.47Å; T83-S87 PolarHBondContact O-N 3.16Å; T83-N303 WeakPolarHBondContact CA-OD1 3.36Å; T83-Q334 HydrophobicContact CG2-CG 4.14Å; T83-S411 WeakPolarHBondContact CG2-O 3.35Å
84C98.1Very high98.4Very high0 Ų03.8 Ų3.80%02%0.023CC..Hα-helixtrans-58.5-63.2-169.6-51.70000114.3D44 S87 R88 N105 K137 H139 N303D44-C84 PolarHBondContact OD1-SG 2.89Å; D44-C84 VanDerWaalsContact OD1-SG 3.39Å; C84-S87 PolarHBondContact O-N 2.58Å; C84-R88 WeakPolarHBondContact O-CB 3.26Å; C84-R88 WeakPolarHBondContact O-CD 3.4Å; C84-R88 WeakPolarHBondContact O-CG 3.5Å; C84-R88 PolarHBondContact O-N 3.22Å; C84-N105 PolarHBondContact N-OD1 3.42Å; C84-K137 PolarHBondContact SG-NZ 3.47Å; C84-K137 VanDerWaalsContact SG-NZ 3.38Å; C84-H139 VanDerWaalsContact CB-ND1 3.34Å; C84-H139 WeakPolarHBondContact CB-ND1 3.49Å; C84-N303 PolarHBondContact N-OD1 3.37Å; C84-N303 VanDerWaalsContact N-OD1 3.17Å
85S98.7Very high98.4Very high0 Ų03.8 Ų3.80%02%0.023CC..Hα-helixtrans-63-47.2-172.4-55.80000112.6S87 R88 A89 N105 F106 H139 L140S85-S87 VanDerWaalsContact C-N 3.32Å; S85-S87 PolarHBondContact O-N 2.98Å; S85-R88 PolarHBondContact O-N 2.98Å; S85-A89 VanDerWaalsContact O-CB 3.31Å; S85-A89 WeakPolarHBondContact O-CB 3.47Å; S85-A89 PolarHBondContact O-N 2.86Å; S85-N105 PolarHBondContact N-OD1 3.07Å; S85-N105 WeakPolarHBondContact OG-CA 3.43Å; S85-F106 PolarHBondContact OG-N 3.47Å; S85-H139 WeakPolarHBondContact CB-O 3.38Å; S85-H139 PolarHBondContact OG-CD2 2.88Å; S85-H139 PolarHBondContact OG-NE2 2.92Å; S85-H139 PolarHBondContact OG-O 3.4Å; S85-L140 VanDerWaalsContact O-CD2 3.29Å; S85-L140 WeakPolarHBondContact O-CD2 3.12Å
86P98.7Very high98.5Very high5 Ų52.5 Ų2.53%0.0322%0.015CC..Hα-helixtrans-62.7-37.6178.9-25.538.5000113A81 T83 S90 V102 T103A81-P86 HydrophobicContact CB-CB 3.64Å; T83-P86 WeakPolarHBondContact OG1-CD 3.33Å; T83-P86 WeakPolarHBondContact OG1-CG 3.41Å; P86-S90 WeakPolarHBondContact O-CB 3.36Å; P86-S90 PolarHBondContact O-N 3.2Å; P86-S90 PolarHBondContact O-OG 3.16Å; P86-V102 WeakPolarHBondContact CB-O 3.17Å; P86-V102 HydrophobicContact CG-CG1 4.39Å; P86-T103 VanDerWaalsContact CG-C 3.41Å; P86-T103 WeakPolarHBondContact CG-O 3.47Å
87S98.6Very high98.5Very high0 Ų01.6 Ų1.60%01%0.011CC..Hα-helixtrans-68.7-44.1177.3-1680000112.1T83 C84 S85 S90 L91 D302T83-S87 VanDerWaalsContact O-CB 3.23Å; T83-S87 WeakPolarHBondContact O-CB 3.47Å; T83-S87 PolarHBondContact O-N 3.16Å; C84-S87 PolarHBondContact O-N 2.58Å; S85-S87 VanDerWaalsContact C-N 3.32Å; S85-S87 PolarHBondContact O-N 2.98Å; S87-S90 WeakPolarHBondContact O-CB 3.4Å; S87-S90 PolarHBondContact O-N 3.25Å; S87-L91 PolarHBondContact O-N 3.41Å; S87-D302 WeakPolarHBondContact CB-O 3.31Å; S87-D302 PolarHBondContact OG-O 2.91Å
88R98.9Very high98.4Very high0 Ų04 Ų40%02%0.024CC..Hα-helixtrans-63.8-40.8175.9-69.8164.3-171.2-97.1-8.3112.3L42 D44 C84 S85 S90 L91 L92 K137 L140 D302L42-R88 HydrophobicContact CD2-CG 3.85Å; D44-R88 IonicContact OD1-NH2 3.54Å; D44-R88 PolarHBondContact OD1-NH2 2.87Å; D44-R88 IonicContact OD2-NH2 3.18Å; C84-R88 WeakPolarHBondContact O-CB 3.26Å; C84-R88 WeakPolarHBondContact O-CD 3.4Å; C84-R88 WeakPolarHBondContact O-CG 3.5Å; C84-R88 PolarHBondContact O-N 3.22Å; S85-R88 PolarHBondContact O-N 2.98Å; R88-S90 VanDerWaalsContact C-N 3.3Å; R88-S90 PolarHBondContact O-N 3.46Å; R88-L91 PolarHBondContact O-N 2.98Å; R88-L92 WeakPolarHBondContact O-CG 3.34Å; R88-L92 PolarHBondContact O-N 3.21Å; R88-L92 VanDerWaalsContact O-N 3.1Å; R88-K137 PolarHBondContact NH1-O 2.95Å; R88-L140 HydrophobicContact CB-CD1 4.26Å; R88-L140 HydrophobicContact CB-CD2 4.33Å; R88-L140 HydrophobicContact CB-CG 4.33Å; R88-D302 IonicContact CZ-OD2 2.66Å; R88-D302 IonicContact NE-OD2 3.82Å; R88-D302 PolarHBondContact NE-OD2 3.43Å; R88-D302 IonicContact NH2-OD2 2.9Å; R88-D302 PolarHBondContact NH2-OD2 3.46Å
89A98.9Very high98.4Very high0 Ų04.2 Ų4.20%03%0.025CC..Hα-helixtrans-60.4-44.3173.700000110.6S85 L92 T93 V102 L114 L140S85-A89 VanDerWaalsContact O-CB 3.31Å; S85-A89 WeakPolarHBondContact O-CB 3.47Å; S85-A89 PolarHBondContact O-N 2.86Å; A89-L92 PolarHBondContact O-N 2.88Å; A89-T93 WeakPolarHBondContact O-CB 3.48Å; A89-T93 WeakPolarHBondContact O-CG2 3.46Å; A89-T93 PolarHBondContact O-N 2.9Å; A89-T93 PolarHBondContact O-OG1 2.94Å; A89-V102 HydrophobicContact CB-CB 3.73Å; A89-V102 HydrophobicContact CB-CG1 4.04Å; A89-V102 HydrophobicContact CB-CG2 3.85Å; A89-L114 HydrophobicContact CB-CD1 4.03Å; A89-L140 HydrophobicContact CB-CD2 3.71Å
90S98.8Very high98.4Very high1 Ų14.2 Ų4.21%0.0072%0.024CC..Hα-helixtrans-66.2-39179.8-58.80000112.7A80 P86 S87 R88 T93 G94 R95A80-S90 WeakPolarHBondContact CB-OG 3.44Å; P86-S90 WeakPolarHBondContact O-CB 3.36Å; P86-S90 PolarHBondContact O-N 3.2Å; P86-S90 PolarHBondContact O-OG 3.16Å; S87-S90 WeakPolarHBondContact O-CB 3.4Å; S87-S90 PolarHBondContact O-N 3.25Å; R88-S90 VanDerWaalsContact C-N 3.3Å; R88-S90 PolarHBondContact O-N 3.46Å; S90-T93 PolarHBondContact O-N 3.04Å; S90-G94 VanDerWaalsContact O-CA 3.31Å; S90-G94 WeakPolarHBondContact O-CA 3.47Å; S90-G94 PolarHBondContact O-N 3.21Å; S90-R95 VanDerWaalsContact CA-O 3.3Å; S90-R95 WeakPolarHBondContact CA-O 3.33Å; S90-R95 WeakPolarHBondContact CB-O 3.33Å; S90-R95 PolarHBondContact OG-O 2.67Å
91L98.9Very high98.4Very high1 Ų14.6 Ų4.61%0.0053%0.028CC..Hα-helixtrans-58.1-49.2172.4-171.5155.2000111I40 L42 S87 R88 T93 Y244 V365 I368I40-L91 HydrophobicContact CG2-CD1 4.43Å; L42-L91 HydrophobicContact CD1-CD1 4Å; L42-L91 HydrophobicContact CD2-CD1 4.1Å; S87-L91 PolarHBondContact O-N 3.41Å; R88-L91 PolarHBondContact O-N 2.98Å; L91-T93 VanDerWaalsContact C-N 3.31Å; L91-T93 PolarHBondContact O-N 2.65Å; L91-Y244 HydrophobicContact CD1-CE2 4.24Å; L91-Y244 HydrophobicContact CD2-CE2 4.16Å; L91-V365 HydrophobicContact CB-CG1 3.41Å; L91-V365 VanDerWaalsContact CB-CG1 3.41Å; L91-V365 HydrophobicContact CD1-CG1 3.86Å; L91-V365 HydrophobicContact CG-CG1 3.8Å; L91-I368 HydrophobicContact CD1-CD1 3.95Å; L91-I368 HydrophobicContact CD2-CG2 4.41Å; L91-I368 HydrophobicContact CG-CD1 4.16Å; L91-I368 HydrophobicContact CG-CG2 4.45Å
92L98.9Very high98.5Very high2 Ų24.3 Ų4.31%0.013%0.026CC..Hα-helixtrans-80-11.6-172.6-67.2174.6000113.7R88 A89 T120 L121 W138 L140 F153 Y244 F369R88-L92 WeakPolarHBondContact O-CG 3.34Å; R88-L92 PolarHBondContact O-N 3.21Å; R88-L92 VanDerWaalsContact O-N 3.1Å; A89-L92 PolarHBondContact O-N 2.88Å; L92-T120 CarbonylContact O-C 3.54Å; L92-T120 WeakPolarHBondContact O-CA 3.22Å; L92-L121 HydrophobicContact CD2-CB 4.48Å; L92-L121 PolarHBondContact O-N 2.9Å; L92-W138 HydrophobicContact CD1-CE3 4.42Å; L92-W138 HydrophobicContact CD1-CH2 3.81Å; L92-W138 HydrophobicContact CD1-CZ3 3.38Å; L92-L140 HydrophobicContact CD1-CD1 3.66Å; L92-F153 HydrophobicContact CD2-CZ 4.3Å; L92-Y244 HydrophobicContact CD1-CE1 4.29Å; L92-Y244 HydrophobicContact CD2-CD1 4.35Å; L92-Y244 HydrophobicContact CD2-CE1 4.28Å; L92-F369 WeakPolarHBondContact O-CD2 3.19Å; L92-F369 WeakPolarHBondContact O-CE2 3.34Å
93T98.8Very high98.5Very high0 Ų05.6 Ų5.60%03%0.034CC..Hα-helixtrans-120.6-14.5-179.360.10000113.9A89 S90 L91 R95 N100 L114 E118 F369 F386A89-T93 WeakPolarHBondContact O-CB 3.48Å; A89-T93 WeakPolarHBondContact O-CG2 3.46Å; A89-T93 PolarHBondContact O-N 2.9Å; A89-T93 PolarHBondContact O-OG1 2.94Å; S90-T93 PolarHBondContact O-N 3.04Å; L91-T93 VanDerWaalsContact C-N 3.31Å; L91-T93 PolarHBondContact O-N 2.65Å; T93-R95 PolarHBondContact O-N 3.28Å; T93-R95 PolarHBondContact OG1-N 3.32Å; T93-R95 PolarHBondContact OG1-O 3.08Å; T93-N100 PolarHBondContact OG1-ND2 3.27Å; T93-L114 HydrophobicContact CG2-CD1 4.1Å; T93-L114 HydrophobicContact CG2-CD2 4.27Å; T93-E118 HydrophobicContact CG2-CB 4.11Å; T93-E118 HydrophobicContact CG2-CG 4.47Å; T93-F369 VanDerWaalsContact C-CD2 3.48Å; T93-F386 WeakPolarHBondContact O-CD1 3.4Å; T93-F386 WeakPolarHBondContact O-CE1 3.37Å
94G98.6Very high98.3Very high0 Ų08.2 Ų8.20%05%0.046CC..SBendtrans64.918.3-172.200000113.9S90 D387 G388S90-G94 VanDerWaalsContact O-CA 3.31Å; S90-G94 WeakPolarHBondContact O-CA 3.47Å; S90-G94 PolarHBondContact O-N 3.21Å; G94-D387 PolarHBondContact O-N 3.16Å; G94-G388 PolarHBondContact O-N 2.69Å
95R98.6Very high98.3Very high1 Ų110.9 Ų10.90%0.0046%0.06CC..SBendtrans-130139.3-170.6-74.1164.160.684.2-5.8110.2S90 T93 R99 N100 E118 R385 F386 D387 D496 N497S90-R95 VanDerWaalsContact CA-O 3.3Å; S90-R95 WeakPolarHBondContact CA-O 3.33Å; S90-R95 WeakPolarHBondContact CB-O 3.33Å; S90-R95 PolarHBondContact OG-O 2.67Å; T93-R95 PolarHBondContact O-N 3.28Å; T93-R95 PolarHBondContact OG1-N 3.32Å; T93-R95 PolarHBondContact OG1-O 3.08Å; R95-R99 HydrophobicContact CB-CB 4.12Å; R95-R99 PolarHBondContact NH2-O 3.35Å; R95-R99 VanDerWaalsContact NH2-O 3.11Å; R95-N100 HydrophobicContact CB-CB 4.24Å; R95-N100 PolarHBondContact O-ND2 3.08Å; R95-E118 IonicContact CZ-OE1 3.02Å; R95-E118 IonicContact NE-OE1 3.78Å; R95-E118 PolarHBondContact NE-OE1 2.77Å; R95-E118 IonicContact NE-OE2 2.64Å; R95-E118 PolarHBondContact NE-OE2 2.75Å; R95-E118 IonicContact NH2-OE1 3.36Å; R95-E118 PolarHBondContact NH2-OE1 2.91Å; R95-E118 VanDerWaalsContact NH2-OE1 3.17Å; R95-R385 WeakPolarHBondContact CG-O 3.45Å; R95-R385 PolarHBondContact NH1-O 3.18Å; R95-F386 HydrophobicContact CG-CD1 4.15Å; R95-F386 HydrophobicContact CG-CE1 4.49Å; R95-D387 WeakPolarHBondContact CA-OD2 3.05Å; R95-D496 IonicContact CZ-OD2 2.76Å; R95-D496 IonicContact NH1-OD1 3.4Å; R95-D496 IonicContact NH1-OD2 3.53Å; R95-D496 PolarHBondContact NH1-OD2 2.8Å; R95-D496 IonicContact NH2-OD2 3.38Å; R95-N497 PolarHBondContact NH2-O 2.95Å
96L98.6Very high98.3Very high4 Ų411.2 Ų11.22%0.0216%0.062CC..  trans-64158.9175.5-73169.2000112L98 R99 N100 L366 D387 F407 P409 L420L96-L98 PolarHBondContact O-N 3.35Å; L96-R99 WeakPolarHBondContact O-CA 3.49Å; L96-R99 WeakPolarHBondContact O-CB 3.23Å; L96-R99 PolarHBondContact O-N 2.83Å; L96-N100 PolarHBondContact O-N 3.33Å; L96-N100 PolarHBondContact O-ND2 3.49Å; L96-L366 HydrophobicContact CD2-CD1 3.89Å; L96-L366 HydrophobicContact CD2-CD2 4.48Å; L96-L366 HydrophobicContact CG-CD1 4.23Å; L96-D387 WeakPolarHBondContact CB-OD2 3.38Å; L96-D387 HydrophobicContact CD1-CB 4.28Å; L96-D387 HydrophobicContact CG-CB 4.03Å; L96-D387 WeakPolarHBondContact CG-OD2 3.45Å; L96-D387 PolarHBondContact N-OD2 2.99Å; L96-F407 HydrophobicContact CD1-CB 4.49Å; L96-P409 HydrophobicContact CD2-CG 3.96Å; L96-L420 HydrophobicContact CD1-CD1 4.41Å
97G97.9Very high98.1Very high4 Ų411.8 Ų11.84%0.0417%0.067CC..Hα-helixtrans-53.9-35.517900000114.7R99 N100 G101 V102G97-R99 PolarHBondContact O-N 2.82Å; G97-N100 WeakPolarHBondContact CA-OD1 3.46Å; G97-G101 CarbonylContact O-C 3.56Å; G97-G101 VanDerWaalsContact O-CA 3.31Å; G97-G101 WeakPolarHBondContact O-CA 3.45Å; G97-G101 PolarHBondContact O-N 3.47Å; G97-V102 WeakPolarHBondContact CA-O 3.4Å; G97-V102 PolarHBondContact O-N 2.85Å
98L97.8Very high98Very high51 Ų5112.2 Ų12.227%0.2677%0.07SC..Hα-helixtrans-68-18.5175.4-67-177.3000114L96 T103 G418 L420 I493L96-L98 PolarHBondContact O-N 3.35Å; L98-T103 HydrophobicContact CD2-CG2 4.36Å; L98-G418 VanDerWaalsContact CD1-O 3.3Å; L98-G418 WeakPolarHBondContact CD1-O 3.33Å; L98-G418 WeakPolarHBondContact CD2-O 3.44Å; L98-G418 WeakPolarHBondContact CG-O 3.29Å; L98-L420 HydrophobicContact CD1-CD1 4.33Å; L98-L420 HydrophobicContact CD1-CD2 4.4Å; L98-L420 HydrophobicContact CD1-CG 3.81Å; L98-I493 HydrophobicContact CB-CD1 4.31Å; L98-I493 HydrophobicContact CB-CG2 4.11Å; L98-I493 HydrophobicContact CD1-CD1 4.18Å
99R98.4Very high97.8Very high5 Ų513.4 Ų13.42%0.0198%0.077CC..Hα-helixtrans-97.7-44.3175.9-64.5-172.5-164.3-84.2-0.6112.2R95 L96 G97 G101 D387 D492 I493 D496 I498 S499R95-R99 HydrophobicContact CB-CB 4.12Å; R95-R99 PolarHBondContact NH2-O 3.35Å; R95-R99 VanDerWaalsContact NH2-O 3.11Å; L96-R99 WeakPolarHBondContact O-CA 3.49Å; L96-R99 WeakPolarHBondContact O-CB 3.23Å; L96-R99 PolarHBondContact O-N 2.83Å; G97-R99 PolarHBondContact O-N 2.82Å; R99-G101 VanDerWaalsContact C-N 3.33Å; R99-D387 WeakPolarHBondContact CD-OD2 3.44Å; R99-D387 IonicContact CZ-OD1 3.55Å; R99-D387 VanDerWaalsContact CZ-OD1 3.29Å; R99-D387 IonicContact NE-OD1 3.12Å; R99-D387 PolarHBondContact NE-OD1 2.04Å; R99-D387 IonicContact NE-OD2 2.93Å; R99-D387 PolarHBondContact NE-OD2 3.2Å; R99-D387 IonicContact NH2-OD1 3.46Å; R99-D387 PolarHBondContact NH2-OD1 2.93Å; R99-D492 IonicContact CZ-OD2 2.81Å; R99-D492 IonicContact NH1-OD2 3.98Å; R99-D492 PolarHBondContact NH1-OD2 3.38Å; R99-D492 IonicContact NH2-OD2 3.29Å; R99-D492 PolarHBondContact NH2-OD2 2.8Å; R99-I493 HydrophobicContact CG-CG1 4.16Å; R99-I493 HydrophobicContact CG-CG2 4.45Å; R99-I493 VanDerWaalsContact CZ-CG1 3.47Å; R99-D496 WeakPolarHBondContact CD-OD2 3.26Å; R99-D496 IonicContact CZ-OD2 3.07Å; R99-D496 IonicContact NH1-OD2 3.38Å; R99-D496 PolarHBondContact NH1-OD2 3.05Å; R99-D496 VanDerWaalsContact NH1-OD2 3.13Å; R99-I498 WeakPolarHBondContact O-CA 2.92Å; R99-S499 PolarHBondContact O-N 3.27Å
100N98.4Very high97.8Very high0 Ų013.5 Ų13.50%08%0.077CC..Hα-helixtrans-83.6-11-177.573.736.2000113.4T93 R95 L96 G97 V102 P115 E118 S499T93-N100 PolarHBondContact OG1-ND2 3.27Å; R95-N100 HydrophobicContact CB-CB 4.24Å; R95-N100 PolarHBondContact O-ND2 3.08Å; L96-N100 PolarHBondContact O-N 3.33Å; L96-N100 PolarHBondContact O-ND2 3.49Å; G97-N100 WeakPolarHBondContact CA-OD1 3.46Å; N100-V102 WeakPolarHBondContact OD1-CB 3.27Å; N100-V102 PolarHBondContact OD1-N 2.98Å; N100-P115 VanDerWaalsContact O-CD 3.25Å; N100-P115 WeakPolarHBondContact O-CD 3.43Å; N100-P115 VanDerWaalsContact O-CG 3.27Å; N100-P115 WeakPolarHBondContact O-CG 3.36Å; N100-E118 WeakPolarHBondContact CA-OE1 3.37Å; N100-E118 HydrophobicContact CB-CG 4.14Å; N100-S499 WeakPolarHBondContact O-CB 3.29Å
101G98.1Very high97.7Very high10 Ų1015.2 Ų15.210%0.1039%0.088CC..SBendtrans88.8-8.1176.400000115.1G97 R99 S499 A501G97-G101 CarbonylContact O-C 3.56Å; G97-G101 VanDerWaalsContact O-CA 3.31Å; G97-G101 WeakPolarHBondContact O-CA 3.45Å; G97-G101 PolarHBondContact O-N 3.47Å; R99-G101 VanDerWaalsContact C-N 3.33Å; G101-S499 WeakPolarHBondContact CA-O 3.27Å; G101-S499 PolarHBondContact N-O 3Å; G101-A501 WeakPolarHBondContact O-CB 3.46Å; G101-A501 PolarHBondContact O-N 2.83Å
102V98.7Very high97.6Very high0 Ų015.1 Ų15.10%09%0.087CC..  trans-96.399.9-177.9-173.30000110P86 A89 G97 N100 F106 L114 L140 A501 Y503P86-V102 WeakPolarHBondContact CB-O 3.17Å; P86-V102 HydrophobicContact CG-CG1 4.39Å; A89-V102 HydrophobicContact CB-CB 3.73Å; A89-V102 HydrophobicContact CB-CG1 4.04Å; A89-V102 HydrophobicContact CB-CG2 3.85Å; G97-V102 WeakPolarHBondContact CA-O 3.4Å; G97-V102 PolarHBondContact O-N 2.85Å; N100-V102 WeakPolarHBondContact OD1-CB 3.27Å; N100-V102 PolarHBondContact OD1-N 2.98Å; V102-F106 HydrophobicContact CG1-CE2 3.68Å; V102-F106 HydrophobicContact CG1-CZ 4.11Å; V102-F106 HydrophobicContact CG2-CE2 4.13Å; V102-F106 HydrophobicContact CG2-CZ 4.09Å; V102-L114 HydrophobicContact CG2-CD1 3.84Å; V102-L140 HydrophobicContact CG1-CD2 4.44Å; V102-A501 HydrophobicContact CG2-CB 4.34Å; V102-Y503 WeakPolarHBondContact CA-OH 3.24Å
103T97.7Very high97.6Very high29 Ų2915 Ų1518%0.1789%0.087CC..  trans-107.7-18.3-176.759.60000114P86 L98 Y503P86-T103 VanDerWaalsContact CG-C 3.41Å; P86-T103 WeakPolarHBondContact CG-O 3.47Å; L98-T103 HydrophobicContact CD2-CG2 4.36Å; T103-Y503 PolarHBondContact N-OH 2.93Å
104H95Very high97.6Very high59 Ų5915.1 Ų15.127%0.2739%0.087SC..SBendtrans-145.7170.8176.160.7-78.2000112.3F417 Y503H104-F417 HydrophobicContact CB-CB 4.41Å; H104-F417 HydrophobicContact CB-CD1 3.86Å; H104-F417 HydrophobicContact CB-CD2 4.4Å; H104-F417 HydrophobicContact CB-CE1 4.16Å; H104-F417 HydrophobicContact CB-CG 3.99Å; H104-Y503 AromaticContact CD2-CD1 3.82Å; H104-Y503 AromaticContact CD2-CE1 3.62Å; H104-Y503 AromaticContact CE1-CD1 3.46Å; H104-Y503 VanDerWaalsContact CE1-CD1 3.46Å; H104-Y503 WeakPolarHBondContact CE1-CD1 3.37Å; H104-Y503 AromaticContact CE1-CD2 3.28Å; H104-Y503 WeakPolarHBondContact CE1-CD2 3.22Å; H104-Y503 AromaticContact CE1-CE1 3.4Å; H104-Y503 WeakPolarHBondContact CE1-CE1 3.42Å; H104-Y503 AromaticContact CE1-CE2 3.19Å; H104-Y503 WeakPolarHBondContact CE1-CE2 3.3Å; H104-Y503 AromaticContact CE1-CG 3.38Å; H104-Y503 AromaticContact CE1-CZ 3.24Å; H104-Y503 AromaticContact CG-CE1 3.87Å; H104-Y503 AromaticContact CG-CZ 3.88Å; H104-Y503 PolarHBondContact N-OH 2.02Å; H104-Y503 VanDerWaalsContact N-OH 3.12Å; H104-Y503 AromaticContact ND1-CE1 3.72Å; H104-Y503 AromaticContact ND1-CE2 3.59Å; H104-Y503 AromaticContact ND1-CZ 3.34Å; H104-Y503 VanDerWaalsContact ND1-CZ 3.34Å; H104-Y503 AromaticContact NE2-CD1 3.15Å; H104-Y503 WeakPolarHBondContact NE2-CD1 3Å; H104-Y503 AromaticContact NE2-CD2 3.81Å; H104-Y503 AromaticContact NE2-CE1 3.34Å; H104-Y503 VanDerWaalsContact NE2-CE1 3.34Å; H104-Y503 WeakPolarHBondContact NE2-CE1 3.21Å; H104-Y503 AromaticContact NE2-CE2 3.95Å; H104-Y503 AromaticContact NE2-CG 3.38Å; H104-Y503 AromaticContact NE2-CZ 3.72Å; H104-Y503 WeakPolarHBondContact O-CE1 3.49Å; H104-Y503 PolarHBondContact O-OH 3.46Å
105N97.3Very high97.6Very high57 Ų5715.4 Ų15.431%0.3059%0.089SC..PPolyproline II helixtrans-68.4141.4-177.2-72.4-5.4000112.4C84 S85C84-N105 PolarHBondContact N-OD1 3.42Å; S85-N105 PolarHBondContact N-OD1 3.07Å; S85-N105 WeakPolarHBondContact OG-CA 3.43Å
106F98.1Very high97.5Very high6 Ų619.2 Ų19.23%0.02611%0.109CC..PPolyproline II helixtrans-80.3151.3173.2-65.5-75000111.3S85 V102 G113 H139 L140 M165 A501 Y503S85-F106 PolarHBondContact OG-N 3.47Å; V102-F106 HydrophobicContact CG1-CE2 3.68Å; V102-F106 HydrophobicContact CG1-CZ 4.11Å; V102-F106 HydrophobicContact CG2-CE2 4.13Å; V102-F106 HydrophobicContact CG2-CZ 4.09Å; F106-G113 VanDerWaalsContact CZ-CA 3.49Å; F106-G113 WeakPolarHBondContact CZ-O 3.42Å; F106-H139 PolarHBondContact O-NE2 2.9Å; F106-L140 HydrophobicContact CE2-CD2 4.44Å; F106-M165 VanDerWaalsContact O-CE 3.32Å; F106-M165 WeakPolarHBondContact O-CE 3.33Å; F106-A501 HydrophobicContact CE1-CB 4.17Å; F106-A501 HydrophobicContact CZ-CB 3.9Å; F106-Y503 AromaticContact CD1-CD1 3.69Å; F106-Y503 HydrophobicContact CD1-CD1 3.69Å; F106-Y503 AromaticContact CD1-CE1 3.56Å; F106-Y503 HydrophobicContact CD1-CE1 3.56Å; F106-Y503 AromaticContact CE1-CD1 3.58Å; F106-Y503 HydrophobicContact CE1-CD1 3.58Å; F106-Y503 AromaticContact CE1-CE1 3.28Å; F106-Y503 HydrophobicContact CE1-CE1 3.28Å; F106-Y503 HydrophobicContact CE1-CG 4.42Å; F106-Y503 AromaticContact CE1-CZ 3.93Å; F106-Y503 HydrophobicContact CG-CE1 4.3Å; F106-Y503 AromaticContact CZ-CE1 3.82Å; F106-Y503 HydrophobicContact CZ-CE1 3.82Å
107A95.7Very high97.5Very high18 Ų1822.7 Ų22.715%0.14913%0.128CC..PPolyproline II helixtrans-95.3166.4177.700000111.8T109 S110 Q505A107-T109 PolarHBondContact O-N 3.13Å; A107-S110 PolarHBondContact N-OG 3.25Å; A107-S110 VanDerWaalsContact O-CB 3.32Å; A107-S110 WeakPolarHBondContact O-CB 3.41Å; A107-S110 PolarHBondContact O-N 3.1Å; A107-S110 PolarHBondContact O-OG 3.32Å; A107-Q505 HydrophobicContact CB-CG 4.45Å
108V95.4Very high97.5Very high9 Ų922.7 Ų22.76%0.05513%0.127CC..THydrogen-bonded Turntrans-62.1-21.6172.8-53.30000113H142 Y161 M165 Y196V108-H142 PolarHBondContact O-CE1 3.36Å; V108-H142 PolarHBondContact O-NE2 3.49Å; V108-H142 VanDerWaalsContact O-NE2 3.15Å; V108-Y161 HydrophobicContact CB-CD1 4.49Å; V108-Y161 HydrophobicContact CB-CE1 3.97Å; V108-Y161 HydrophobicContact CG1-CD1 4.16Å; V108-Y161 HydrophobicContact CG1-CD2 4.07Å; V108-Y161 HydrophobicContact CG1-CE1 3.89Å; V108-Y161 HydrophobicContact CG1-CE2 3.76Å; V108-Y161 HydrophobicContact CG1-CG 4.25Å; V108-M165 HydrophobicContact CG1-CB 3.67Å; V108-M165 HydrophobicContact CG1-CE 3.95Å; V108-M165 WeakPolarHBondContact CG1-O 3.49Å; V108-Y196 HydrophobicContact CG1-CD1 4.23Å; V108-Y196 HydrophobicContact CG1-CE1 3.86Å; V108-Y196 HydrophobicContact CG2-CD1 4.28Å; V108-Y196 HydrophobicContact CG2-CE1 3.87Å
109T96.4Very high97.5Very high24 Ų2422 Ų2215%0.14713%0.125CC..THydrogen-bonded Turntrans-98.31.4178.152.80000112.5A107 V111 Q505 D506 V509A107-T109 PolarHBondContact O-N 3.13Å; T109-V111 PolarHBondContact O-N 3.39Å; T109-Q505 CarbonylContact O-C 3.44Å; T109-Q505 VanDerWaalsContact O-CA 3.23Å; T109-Q505 WeakPolarHBondContact O-CA 3.49Å; T109-Q505 WeakPolarHBondContact OG1-CG 3.33Å; T109-Q505 PolarHBondContact OG1-OE1 3.16Å; T109-D506 PolarHBondContact O-N 3.43Å; T109-V509 VanDerWaalsContact O-CG2 3.26Å; T109-V509 WeakPolarHBondContact O-CG2 3.44Å
110S96.9Very high97.5Very high2 Ų221.8 Ų21.81%0.01412%0.124CC..BIsolated β-bridgetrans-64.7122.2-178.8-750000111.5A107 T504A107-S110 PolarHBondContact N-OG 3.25Å; A107-S110 VanDerWaalsContact O-CB 3.32Å; A107-S110 WeakPolarHBondContact O-CB 3.41Å; A107-S110 PolarHBondContact O-N 3.1Å; A107-S110 PolarHBondContact O-OG 3.32Å; S110-T504 WeakPolarHBondContact CA-O 3.4Å
111V97.3Very high97.5Very high37 Ų3721.9 Ų21.922%0.22412%0.124CC..SBendtrans-73-38.9174.9-178.70000110.5T109 Y146 T504 D506 V509T109-V111 PolarHBondContact O-N 3.39Å; V111-Y146 WeakPolarHBondContact O-CE2 3.45Å; V111-T504 HydrophobicContact CG2-CG2 4.24Å; V111-T504 PolarHBondContact N-O 3.16Å; V111-D506 HydrophobicContact CG2-CB 3.53Å; V111-V509 HydrophobicContact CG2-CG1 4.22Å; V111-V509 HydrophobicContact CG2-CG2 4.28Å
112G97.5Very high97.6Very high0 Ų021.4 Ų21.40%012%0.12CC..  trans-90.6-173.4178.300000114.6G141 Y146 D502G112-G141 WeakPolarHBondContact O-CA 3.39Å; G112-Y146 VanDerWaalsContact CA-CE2 3.44Å; G112-D502 VanDerWaalsContact CA-O 3.24Å; G112-D502 WeakPolarHBondContact CA-O 3.42Å
113G98.2Very high97.6Very high0 Ų023.1 Ų23.10%013%0.128CC..  trans-169.5-156.7-178.300000111.7F106 P115 L140 Y146F106-G113 VanDerWaalsContact CZ-CA 3.49Å; F106-G113 WeakPolarHBondContact CZ-O 3.42Å; G113-P115 WeakPolarHBondContact O-CD 3.49Å; G113-P115 VanDerWaalsContact O-N 3.14Å; G113-L140 CarbonylContact C-O 3.59Å; G113-L140 WeakPolarHBondContact CA-O 3.38Å; G113-Y146 VanDerWaalsContact CA-CD1 3.45Å
114L98.7Very high97.6Very high1 Ų122.1 Ų22.11%0.00512%0.122CC..SBendtrans-53120169.2175.769.9000108.8A89 T93 V102 L116 E118 T120 L140 Y146A89-L114 HydrophobicContact CB-CD1 4.03Å; T93-L114 HydrophobicContact CG2-CD1 4.1Å; T93-L114 HydrophobicContact CG2-CD2 4.27Å; V102-L114 HydrophobicContact CG2-CD1 3.84Å; L114-L116 PolarHBondContact O-N 2.6Å; L114-E118 HydrophobicContact CD1-CB 4.33Å; L114-E118 HydrophobicContact CD1-CG 4.44Å; L114-E118 HydrophobicContact CG-CB 4.43Å; L114-T120 HydrophobicContact CD2-CG2 3.84Å; L114-L140 HydrophobicContact CB-CB 4.1Å; L114-L140 HydrophobicContact CD2-CD1 4.43Å; L114-L140 PolarHBondContact N-O 2.92Å; L114-Y146 VanDerWaalsContact O-CD1 3.26Å; L114-Y146 WeakPolarHBondContact O-CD1 3.16Å; L114-Y146 WeakPolarHBondContact O-CE1 3.33Å
115P98.4Very high97.8Very high7 Ų719.3 Ų19.35%0.04511%0.109CC..  trans-50133-174.3-34.240.5000113.1N100 G113 N117 E118 R151 S500 A501N100-P115 VanDerWaalsContact O-CD 3.25Å; N100-P115 WeakPolarHBondContact O-CD 3.43Å; N100-P115 VanDerWaalsContact O-CG 3.27Å; N100-P115 WeakPolarHBondContact O-CG 3.36Å; G113-P115 WeakPolarHBondContact O-CD 3.49Å; G113-P115 VanDerWaalsContact O-N 3.14Å; P115-N117 WeakPolarHBondContact CB-OD1 3.38Å; P115-N117 PolarHBondContact O-N 2.93Å; P115-N117 VanDerWaalsContact O-N 3.11Å; P115-E118 HydrophobicContact CB-CG 4.42Å; P115-E118 WeakPolarHBondContact O-CB 3.4Å; P115-E118 PolarHBondContact O-N 3.05Å; P115-R151 PolarHBondContact O-NH2 2.78Å; P115-R151 VanDerWaalsContact O-NH2 3.13Å; P115-S500 VanDerWaalsContact CG-C 3.48Å; P115-S500 WeakPolarHBondContact CG-O 3.31Å; P115-A501 HydrophobicContact CG-CB 4.16Å
116L97.6Very high97.8Very high80 Ų8020.4 Ų20.442%0.41911%0.112SC..THydrogen-bonded Turntrans-66.2-17.2-174.3-58.6-179.7000113.4L114 E118 S145 Y146L114-L116 PolarHBondContact O-N 2.6Å; L116-E118 VanDerWaalsContact C-N 3.33Å; L116-S145 WeakPolarHBondContact CD2-O 3.18Å; L116-Y146 HydrophobicContact CD2-CD1 3.65Å; L116-Y146 HydrophobicContact CD2-CE1 3.62Å; L116-Y146 HydrophobicContact CD2-CG 4.37Å; L116-Y146 HydrophobicContact CG-CD1 4.29Å; L116-Y146 HydrophobicContact CG-CE1 3.72Å
117N96.9Very high97.8Very high78 Ų7827.9 Ų27.942%0.41715%0.147SC..THydrogen-bonded Turntrans-79.4-13.5173.871-23.3000113P115 R384 S499P115-N117 WeakPolarHBondContact CB-OD1 3.38Å; P115-N117 PolarHBondContact O-N 2.93Å; P115-N117 VanDerWaalsContact O-N 3.11Å; N117-R384 PolarHBondContact ND2-NH2 3.28Å; N117-R384 PolarHBondContact O-NH2 3.18Å; N117-S499 PolarHBondContact ND2-OG 3.27Å; N117-S499 WeakPolarHBondContact OD1-CB 3.47Å; N117-S499 PolarHBondContact OD1-OG 2.8Å
118E98.3Very high98Very high3 Ų328.1 Ų28.11%0.01415%0.149CC..SBendtrans-76.5143.1170.5-73.7-65.5166.100110.5T93 R95 N100 L114 P115 L116 R151 R384 S499T93-E118 HydrophobicContact CG2-CB 4.11Å; T93-E118 HydrophobicContact CG2-CG 4.47Å; R95-E118 IonicContact CZ-OE1 3.02Å; R95-E118 IonicContact NE-OE1 3.78Å; R95-E118 PolarHBondContact NE-OE1 2.77Å; R95-E118 IonicContact NE-OE2 2.64Å; R95-E118 PolarHBondContact NE-OE2 2.75Å; R95-E118 IonicContact NH2-OE1 3.36Å; R95-E118 PolarHBondContact NH2-OE1 2.91Å; R95-E118 VanDerWaalsContact NH2-OE1 3.17Å; N100-E118 WeakPolarHBondContact CA-OE1 3.37Å; N100-E118 HydrophobicContact CB-CG 4.14Å; L114-E118 HydrophobicContact CD1-CB 4.33Å; L114-E118 HydrophobicContact CD1-CG 4.44Å; L114-E118 HydrophobicContact CG-CB 4.43Å; P115-E118 HydrophobicContact CB-CG 4.42Å; P115-E118 WeakPolarHBondContact O-CB 3.4Å; P115-E118 PolarHBondContact O-N 3.05Å; L116-E118 VanDerWaalsContact C-N 3.33Å; E118-R151 PolarHBondContact O-NH2 3.46Å; E118-R384 IonicContact OE1-CZ 2.86Å; E118-R384 IonicContact OE1-NH1 3.28Å; E118-R384 PolarHBondContact OE1-NH1 3.03Å; E118-R384 IonicContact OE2-CZ 3.95Å; E118-R384 IonicContact OE2-NE 3.04Å; E118-R384 IonicContact OE2-NH1 3.53Å; E118-R384 PolarHBondContact OE2-NH1 3.02Å; E118-S499 PolarHBondContact OE1-OG 3.38Å; E118-S499 VanDerWaalsContact OE1-OG 3.08Å
119T98.2Very high98Very high38 Ų3829.5 Ų29.523%0.23316%0.164CC..PPolyproline II helixtrans-102.8122177.3-51.90000109.7E123 V124 P381T119-E123 VanDerWaalsContact CA-OE2 3.29Å; T119-E123 WeakPolarHBondContact CA-OE2 3.39Å; T119-E123 HydrophobicContact CG2-CB 3.95Å; T119-V124 HydrophobicContact CG2-CG2 3.81Å; T119-P381 HydrophobicContact CG2-CG 4.04Å
120T98.8Very high98.2Very high0 Ų028.4 Ų28.40%016%0.158CC..PPolyproline II helixtrans-81.1159.4-179.978.50000112.1L92 L114 A122 E123 V124 R151L92-T120 CarbonylContact O-C 3.54Å; L92-T120 WeakPolarHBondContact O-CA 3.22Å; L114-T120 HydrophobicContact CD2-CG2 3.84Å; T120-A122 PolarHBondContact O-N 3.17Å; T120-A122 PolarHBondContact OG1-N 2.9Å; T120-E123 PolarHBondContact N-OE2 3.07Å; T120-E123 PolarHBondContact O-N 3.19Å; T120-E123 VanDerWaalsContact O-N 3.13Å; T120-E123 WeakPolarHBondContact OG1-CG 3.25Å; T120-E123 PolarHBondContact OG1-N 2.86Å; T120-E123 VanDerWaalsContact OG1-N 3.1Å; T120-V124 PolarHBondContact O-N 3.45Å; T120-V124 VanDerWaalsContact O-N 3.07Å; T120-R151 HydrophobicContact CG2-CB 4.13Å; T120-R151 PolarHBondContact OG1-O 3.4Å
121L98.9Very high98.2Very high1 Ų129.4 Ų29.41%0.00516%0.162CC..Hα-helixtrans-55.4-37.8172.3-179.958.7000111.4I40 L92 V124 L125 I368 F369 V372 V373I40-L121 HydrophobicContact CD1-CD2 3.72Å; L92-L121 HydrophobicContact CD2-CB 4.48Å; L92-L121 PolarHBondContact O-N 2.9Å; L121-V124 PolarHBondContact O-N 3.34Å; L121-L125 HydrophobicContact CD1-CD1 4.35Å; L121-L125 HydrophobicContact CD1-CG 4.24Å; L121-L125 HydrophobicContact CG-CD1 4.39Å; L121-L125 WeakPolarHBondContact O-CG 3.34Å; L121-L125 PolarHBondContact O-N 2.68Å; L121-I368 HydrophobicContact CD2-CG2 4.45Å; L121-F369 HydrophobicContact CB-CD2 3.77Å; L121-F369 HydrophobicContact CB-CE2 4.06Å; L121-F369 HydrophobicContact CD1-CD2 4.22Å; L121-V372 HydrophobicContact CD1-CB 4.07Å; L121-V372 HydrophobicContact CD1-CG1 3.89Å; L121-V372 HydrophobicContact CD2-CB 4.3Å; L121-V372 HydrophobicContact CD2-CG1 4.21Å; L121-V372 HydrophobicContact CG-CG1 4.45Å; L121-V373 HydrophobicContact CD1-CG2 3.85Å
122A98.8Very high98.3Very high0 Ų027.6 Ų27.60%015%0.152CC..Hα-helixtrans-65.8-43178.400000111.4T120 V124 L125 Q126 T132 G152 F153 L242T120-A122 PolarHBondContact O-N 3.17Å; T120-A122 PolarHBondContact OG1-N 2.9Å; A122-V124 PolarHBondContact O-N 2.9Å; A122-L125 PolarHBondContact O-N 2.77Å; A122-Q126 WeakPolarHBondContact O-CB 3.45Å; A122-Q126 PolarHBondContact O-N 2.83Å; A122-T132 HydrophobicContact CB-CG2 4.42Å; A122-G152 WeakPolarHBondContact CB-O 3.4Å; A122-F153 HydrophobicContact CB-CD1 3.81Å; A122-F153 HydrophobicContact CB-CD2 4.04Å; A122-F153 HydrophobicContact CB-CE1 3.62Å; A122-F153 HydrophobicContact CB-CE2 3.85Å; A122-F153 HydrophobicContact CB-CG 4.03Å; A122-F153 HydrophobicContact CB-CZ 3.65Å; A122-L242 HydrophobicContact CB-CD2 4.13Å
123E98.8Very high98.4Very high37 Ų3727.6 Ų27.617%0.17315%0.152CC..Hα-helixtrans-61.6-43.5175.4-69.2171.4133.900111.6T119 T120 L125 Q126 Q127 R151T119-E123 VanDerWaalsContact CA-OE2 3.29Å; T119-E123 WeakPolarHBondContact CA-OE2 3.39Å; T119-E123 HydrophobicContact CG2-CB 3.95Å; T120-E123 PolarHBondContact N-OE2 3.07Å; T120-E123 PolarHBondContact O-N 3.19Å; T120-E123 VanDerWaalsContact O-N 3.13Å; T120-E123 WeakPolarHBondContact OG1-CG 3.25Å; T120-E123 PolarHBondContact OG1-N 2.86Å; T120-E123 VanDerWaalsContact OG1-N 3.1Å; E123-L125 PolarHBondContact O-N 2.9Å; E123-Q126 PolarHBondContact O-N 3.38Å; E123-Q127 VanDerWaalsContact O-CG 3.31Å; E123-Q127 WeakPolarHBondContact O-CG 3.4Å; E123-Q127 PolarHBondContact O-N 3.12Å; E123-R151 IonicContact OE1-NH1 2.74Å
124V98.8Very high98.4Very high8 Ų827.6 Ų27.65%0.04815%0.152CC..Hα-helixtrans-61.3-45.3176.8178.70000111.3T119 T120 L121 A122 A128 F369 V373 A378 P381T119-V124 HydrophobicContact CG2-CG2 3.81Å; T120-V124 PolarHBondContact O-N 3.45Å; T120-V124 VanDerWaalsContact O-N 3.07Å; L121-V124 PolarHBondContact O-N 3.34Å; A122-V124 PolarHBondContact O-N 2.9Å; V124-A128 WeakPolarHBondContact O-CB 3.19Å; V124-A128 PolarHBondContact O-N 2.81Å; V124-A128 VanDerWaalsContact O-N 3.09Å; V124-F369 HydrophobicContact CG2-CZ 3.94Å; V124-V373 HydrophobicContact CB-CG2 4.38Å; V124-V373 HydrophobicContact CG1-CG1 4.22Å; V124-V373 HydrophobicContact CG1-CG2 3.77Å; V124-A378 HydrophobicContact CG1-CB 4Å; V124-P381 HydrophobicContact CG2-CG 3.95Å
125L98.8Very high98.4Very high0 Ų027.6 Ų27.60%015%0.152CC..Hα-helixtrans-73.3-36.5-179-69.1-172.5000112.9F38 L121 A122 E123 Q127 A128 G129 Y130 T132 L242 V372 A376F38-L125 HydrophobicContact CD2-CD1 3.92Å; F38-L125 HydrophobicContact CE2-CD1 4.33Å; F38-L125 HydrophobicContact CE2-CD2 4.42Å; L121-L125 HydrophobicContact CD1-CD1 4.35Å; L121-L125 HydrophobicContact CD1-CG 4.24Å; L121-L125 HydrophobicContact CG-CD1 4.39Å; L121-L125 WeakPolarHBondContact O-CG 3.34Å; L121-L125 PolarHBondContact O-N 2.68Å; A122-L125 PolarHBondContact O-N 2.77Å; E123-L125 PolarHBondContact O-N 2.9Å; L125-Q127 VanDerWaalsContact C-N 3.32Å; L125-Q127 PolarHBondContact O-N 3.01Å; L125-A128 CarbonylContact O-C 3.49Å; L125-A128 WeakPolarHBondContact O-CA 3.38Å; L125-A128 WeakPolarHBondContact O-CB 3.35Å; L125-A128 PolarHBondContact O-N 3.4Å; L125-G129 PolarHBondContact O-N 2.71Å; L125-G129 VanDerWaalsContact O-N 3.16Å; L125-Y130 HydrophobicContact CB-CD1 4.47Å; L125-Y130 HydrophobicContact CB-CD2 4.1Å; L125-Y130 HydrophobicContact CB-CG 3.92Å; L125-Y130 HydrophobicContact CD1-CD1 4.33Å; L125-Y130 HydrophobicContact CD2-CD2 4.15Å; L125-Y130 HydrophobicContact CD2-CE2 4.08Å; L125-Y130 VanDerWaalsContact O-CB 3.28Å; L125-Y130 WeakPolarHBondContact O-CB 3.19Å; L125-Y130 WeakPolarHBondContact O-CD2 3.29Å; L125-Y130 PolarHBondContact O-N 3.26Å; L125-T132 HydrophobicContact CB-CG2 4.49Å; L125-L242 HydrophobicContact CD1-CB 3.77Å; L125-L242 HydrophobicContact CD1-CD1 4.15Å; L125-L242 HydrophobicContact CD1-CD2 3.89Å; L125-L242 HydrophobicContact CD1-CG 4.11Å; L125-V372 HydrophobicContact CD1-CG1 3.76Å; L125-V372 HydrophobicContact CD2-CG1 4.39Å; L125-A376 HydrophobicContact CD2-CB 3.31Å
126Q98.2Very high98.4Very high80 Ų8027.2 Ų27.237%0.37415%0.149SC..Hα-helixtrans-58.2-46.8174-171-172.16000110A122 E123 A128 G129 T132 D154A122-Q126 WeakPolarHBondContact O-CB 3.45Å; A122-Q126 PolarHBondContact O-N 2.83Å; E123-Q126 PolarHBondContact O-N 3.38Å; Q126-A128 PolarHBondContact O-N 3.28Å; Q126-G129 PolarHBondContact O-N 2.97Å; Q126-T132 HydrophobicContact CB-CG2 4.15Å; Q126-D154 PolarHBondContact NE2-OD1 3.05Å
127Q98Very high98.5Very high163 Ų16323.4 Ų23.476%0.76213%0.129SC*.Hα-helixtrans-61.3-31.6173-70.1176.11400112.8E123 L125 G129E123-Q127 VanDerWaalsContact O-CG 3.31Å; E123-Q127 WeakPolarHBondContact O-CG 3.4Å; E123-Q127 PolarHBondContact O-N 3.12Å; L125-Q127 VanDerWaalsContact C-N 3.32Å; L125-Q127 PolarHBondContact O-N 3.01Å; Q127-G129 PolarHBondContact O-N 3.39Å
128A97.9Very high98.6Very high23 Ų2319.8 Ų19.819%0.1911%0.11CC..THydrogen-bonded Turntrans-78.83.4175.300000114.4K35 V124 L125 Q126 Y130 A378K35-A128 PolarHBondContact NZ-O 2.92Å; V124-A128 WeakPolarHBondContact O-CB 3.19Å; V124-A128 PolarHBondContact O-N 2.81Å; V124-A128 VanDerWaalsContact O-N 3.09Å; L125-A128 CarbonylContact O-C 3.49Å; L125-A128 WeakPolarHBondContact O-CA 3.38Å; L125-A128 WeakPolarHBondContact O-CB 3.35Å; L125-A128 PolarHBondContact O-N 3.4Å; Q126-A128 PolarHBondContact O-N 3.28Å; A128-Y130 HydrophobicContact CB-CD2 4.12Å; A128-Y130 HydrophobicContact CB-CE2 4.32Å; A128-A378 HydrophobicContact CB-CB 3.93Å
129G97.4Very high98.6Very high37 Ų3719.8 Ų19.838%0.38111%0.11SC..THydrogen-bonded Turntrans9315.8174.700000115.2L125 Q126 Q127L125-G129 PolarHBondContact O-N 2.71Å; L125-G129 VanDerWaalsContact O-N 3.16Å; Q126-G129 PolarHBondContact O-N 2.97Å; Q127-G129 PolarHBondContact O-N 3.39Å
130Y98.6Very high98.6Very high2 Ų218 Ų181%0.00810%0.099CC..  trans-80.7151.4177.6-74.7-115.1000111.9K35 P36 F38 L125 A128 P240 A376K35-Y130 HydrophobicContact CD-CE2 3.91Å; P36-Y130 WeakPolarHBondContact O-CE1 3.39Å; P36-Y130 PolarHBondContact O-OH 2.96Å; F38-Y130 HydrophobicContact CD2-CD1 4.3Å; F38-Y130 AromaticContact CD2-CE1 3.52Å; F38-Y130 HydrophobicContact CD2-CE1 3.52Å; F38-Y130 AromaticContact CE2-CE1 3.52Å; F38-Y130 HydrophobicContact CE2-CE1 3.52Å; F38-Y130 AromaticContact CE2-CZ 3.62Å; F38-Y130 VanDerWaalsContact CE2-OH 3.29Å; F38-Y130 WeakPolarHBondContact CE2-OH 3.35Å; L125-Y130 HydrophobicContact CB-CD1 4.47Å; L125-Y130 HydrophobicContact CB-CD2 4.1Å; L125-Y130 HydrophobicContact CB-CG 3.92Å; L125-Y130 HydrophobicContact CD1-CD1 4.33Å; L125-Y130 HydrophobicContact CD2-CD2 4.15Å; L125-Y130 HydrophobicContact CD2-CE2 4.08Å; L125-Y130 VanDerWaalsContact O-CB 3.28Å; L125-Y130 WeakPolarHBondContact O-CB 3.19Å; L125-Y130 WeakPolarHBondContact O-CD2 3.29Å; L125-Y130 PolarHBondContact O-N 3.26Å; A128-Y130 HydrophobicContact CB-CD2 4.12Å; A128-Y130 HydrophobicContact CB-CE2 4.32Å; Y130-P240 VanDerWaalsContact CA-O 3.3Å; Y130-P240 WeakPolarHBondContact CA-O 3.43Å; Y130-P240 HydrophobicContact CD1-CB 3.86Å; Y130-P240 HydrophobicContact CD1-CG 4.03Å; Y130-P240 HydrophobicContact CD2-CG 3.89Å; Y130-P240 HydrophobicContact CE1-CB 3.58Å; Y130-P240 HydrophobicContact CE1-CG 4Å; Y130-P240 HydrophobicContact CE2-CB 4.29Å; Y130-P240 HydrophobicContact CE2-CG 3.86Å; Y130-P240 HydrophobicContact CG-CB 4.3Å; Y130-P240 HydrophobicContact CG-CG 3.95Å; Y130-A376 HydrophobicContact CE2-CB 3.87Å
131I98.6Very high98.6Very high22 Ų2218 Ų1811%0.11310%0.1CC..EExtended strand (participates in β ladder)trans-84127.8158.1-58.7178.4000107.8D154 F230 A234 S237 R239 P240 F241 L242I131-D154 WeakPolarHBondContact CA-OD2 3.17Å; I131-F230 HydrophobicContact CG2-CE2 3.86Å; I131-F230 HydrophobicContact CG2-CZ 3.86Å; I131-A234 HydrophobicContact CD1-CB 4.37Å; I131-S237 WeakPolarHBondContact CD1-OG 3.43Å; I131-R239 HydrophobicContact CD1-CB 4.12Å; I131-R239 HydrophobicContact CG1-CB 4.08Å; I131-R239 VanDerWaalsContact CG1-CZ 3.4Å; I131-R239 VanDerWaalsContact CG1-NH2 3.34Å; I131-P240 PolarHBondContact N-O 3.01Å; I131-F241 HydrophobicContact CB-CB 4.32Å; I131-F241 CarbonylContact O-C 3.53Å; I131-F241 WeakPolarHBondContact O-CA 3.2Å; I131-F241 WeakPolarHBondContact O-CB 3.41Å; I131-L242 PolarHBondContact O-N 3.04Å
132T98.9Very high98.4Very high0 Ų018.5 Ų18.50%010%0.102CC..EExtended strand (participates in β ladder)trans-113.7129.4-175.656.40000111.2A122 L125 Q126 G152 F153 D154 Y155 L242A122-T132 HydrophobicContact CB-CG2 4.42Å; L125-T132 HydrophobicContact CB-CG2 4.49Å; Q126-T132 HydrophobicContact CB-CG2 4.15Å; T132-G152 WeakPolarHBondContact CB-O 3.37Å; T132-G152 PolarHBondContact OG1-O 2.7Å; T132-F153 WeakPolarHBondContact OG1-CA 3.45Å; T132-D154 PolarHBondContact N-OD2 2.98Å; T132-D154 WeakPolarHBondContact O-CA 3.39Å; T132-D154 WeakPolarHBondContact O-CB 3.39Å; T132-D154 PolarHBondContact O-N 3.08Å; T132-D154 PolarHBondContact OG1-N 2.9Å; T132-D154 PolarHBondContact OG1-OD2 3.24Å; T132-Y155 PolarHBondContact O-N 3.23Å; T132-L242 CarbonylContact C-O 3.54Å; T132-L242 WeakPolarHBondContact CA-O 3.4Å; T132-L242 HydrophobicContact CG2-CB 4.27Å; T132-L242 HydrophobicContact CG2-CD2 4.4Å
133G98.9Very high98.2Very high0 Ų022.4 Ų22.40%012%0.12CC..EExtended strand (participates in β ladder)trans-131142.3178.500000111.3Y155 F230 L242 L243 Y244G133-Y155 CarbonylContact C-O 3.54Å; G133-Y155 WeakPolarHBondContact CA-O 3.27Å; G133-F230 VanDerWaalsContact CA-CE2 3.48Å; G133-L242 PolarHBondContact N-O 2.76Å; G133-L243 WeakPolarHBondContact O-CA 3.39Å; G133-Y244 PolarHBondContact O-N 3Å
134M98.9Very high98.1Very high0 Ų022.6 Ų22.60%013%0.131CC..EExtended strand (participates in β ladder)trans-124.1129.8170.8177.9170.7176.800110.7K137 W138 P148 F153 Y155 Y156 F157 Y244 A246M134-K137 VanDerWaalsContact CE-C 3.46Å; M134-K137 WeakPolarHBondContact CE-O 3.4Å; M134-W138 HydrophobicContact CE-CB 4.02Å; M134-W138 HydrophobicContact CE-CE3 3.74Å; M134-W138 HydrophobicContact SD-CD2 4.42Å; M134-W138 HydrophobicContact SD-CE3 3.51Å; M134-W138 VanDerWaalsContact SD-CE3 3.51Å; M134-W138 HydrophobicContact SD-CZ3 4Å; M134-P148 HydrophobicContact SD-CB 4.21Å; M134-P148 HydrophobicContact SD-CG 4.23Å; M134-F153 HydrophobicContact CB-CB 4.37Å; M134-F153 HydrophobicContact CB-CD1 3.64Å; M134-F153 HydrophobicContact CB-CD2 4.12Å; M134-F153 HydrophobicContact CB-CE1 3.83Å; M134-F153 HydrophobicContact CB-CE2 4.3Å; M134-F153 HydrophobicContact CB-CG 3.78Å; M134-F153 HydrophobicContact CB-CZ 4.15Å; M134-F153 HydrophobicContact SD-CD2 4.32Å; M134-F153 HydrophobicContact SD-CE2 4.02Å; M134-F153 HydrophobicContact SD-CZ 4.33Å; M134-Y155 PolarHBondContact N-O 3.46Å; M134-Y156 HydrophobicContact CB-CD2 4.06Å; M134-Y156 HydrophobicContact CE-CE2 4.3Å; M134-Y156 HydrophobicContact CG-CD2 3.93Å; M134-Y156 HydrophobicContact CG-CE2 4.23Å; M134-Y156 WeakPolarHBondContact O-CA 3.17Å; M134-Y156 HydrophobicContact SD-CD2 4.27Å; M134-Y156 HydrophobicContact SD-CE2 4.28Å; M134-F157 PolarHBondContact O-N 2.88Å; M134-Y244 CarbonylContact C-O 3.56Å; M134-Y244 VanDerWaalsContact CA-O 3.29Å; M134-Y244 WeakPolarHBondContact CA-O 3.34Å; M134-Y244 HydrophobicContact CE-CD1 4.1Å; M134-Y244 HydrophobicContact CE-CE1 3.87Å; M134-Y244 HydrophobicContact CG-CD1 3.92Å; M134-Y244 HydrophobicContact SD-CD1 3.85Å; M134-Y244 HydrophobicContact SD-CE1 4.1Å; M134-A246 HydrophobicContact CE-CB 3.94Å
135I98.9Very high98Very high0 Ų025.3 Ų25.30%015%0.151CC..EExtended strand (participates in β ladder)trans-121.4125.7173.8-52.4-65.2000108.8Y155 F157 Y223 K226 A227 L243 Y244 V245 A246I135-Y155 HydrophobicContact CD1-CD1 4.07Å; I135-Y155 HydrophobicContact CD1-CE1 3.63Å; I135-F157 CarbonylContact C-O 3.47Å; I135-F157 VanDerWaalsContact CA-O 3.26Å; I135-F157 WeakPolarHBondContact CA-O 3.21Å; I135-F157 HydrophobicContact CD1-CB 3.87Å; I135-Y223 HydrophobicContact CG2-CD1 3.68Å; I135-Y223 HydrophobicContact CG2-CE1 4.46Å; I135-Y223 HydrophobicContact CG2-CG 3.82Å; I135-K226 HydrophobicContact CD1-CB 3.8Å; I135-A227 HydrophobicContact CG1-CB 4.29Å; I135-L243 HydrophobicContact CG1-CD1 3.81Å; I135-Y244 PolarHBondContact N-O 3.08Å; I135-V245 HydrophobicContact CB-CG1 4.46Å; I135-V245 CarbonylContact O-C 3.54Å; I135-V245 WeakPolarHBondContact O-CA 3.48Å; I135-A246 PolarHBondContact O-N 2.85Å
136G98.8Very high98Very high0 Ų027.2 Ų27.20%016%0.158CC..EExtended strand (participates in β ladder)trans101.4-149.4173.400000115.6W138 Y156 F157 G158 I159 Y223 A246G136-W138 PolarHBondContact O-N 2.71Å; G136-Y156 WeakPolarHBondContact O-CE2 3.24Å; G136-F157 PolarHBondContact N-O 2.79Å; G136-G158 WeakPolarHBondContact O-CA 3.48Å; G136-I159 PolarHBondContact O-N 3.17Å; G136-Y223 VanDerWaalsContact CA-CZ 3.49Å; G136-A246 CarbonylContact C-O 3.55Å; G136-A246 WeakPolarHBondContact CA-O 3.09Å
137K98.9Very high98Very high0 Ų023.8 Ų23.80%014%0.142CC..  trans-70.6122.9-166.9175.4-179.7170.3-175.70113.2D44 C84 R88 M134 H139 I159 S162 A246D44-K137 IonicContact OD1-NZ 2.75Å; D44-K137 PolarHBondContact OD1-NZ 3.36Å; D44-K137 WeakPolarHBondContact OD2-CD 3.45Å; D44-K137 WeakPolarHBondContact OD2-CE 3.26Å; D44-K137 IonicContact OD2-NZ 2.74Å; D44-K137 PolarHBondContact OD2-NZ 3.07Å; C84-K137 PolarHBondContact SG-NZ 3.47Å; C84-K137 VanDerWaalsContact SG-NZ 3.38Å; R88-K137 PolarHBondContact NH1-O 2.95Å; M134-K137 VanDerWaalsContact CE-C 3.46Å; M134-K137 WeakPolarHBondContact CE-O 3.4Å; K137-H139 WeakPolarHBondContact CE-ND1 3.34Å; K137-H139 HydrophobicContact CG-CB 4.11Å; K137-I159 WeakPolarHBondContact CA-O 3.47Å; K137-I159 HydrophobicContact CB-CD1 4.34Å; K137-I159 HydrophobicContact CB-CG1 4.02Å; K137-S162 WeakPolarHBondContact CE-OG 3.19Å; K137-S162 PolarHBondContact NZ-OG 3.44Å; K137-A246 PolarHBondContact N-O 2.85Å; K137-A246 WeakPolarHBondContact O-CB 3.43Å
138W98.8Very high98Very high2 Ų216.1 Ų16.11%0.00811%0.106CC..  trans-81.7-70.1175.2178.9-131.6000113.7L92 M134 G136 L140 G141 Y146 P148 R151 F153 I159L92-W138 HydrophobicContact CD1-CE3 4.42Å; L92-W138 HydrophobicContact CD1-CH2 3.81Å; L92-W138 HydrophobicContact CD1-CZ3 3.38Å; M134-W138 HydrophobicContact CE-CB 4.02Å; M134-W138 HydrophobicContact CE-CE3 3.74Å; M134-W138 HydrophobicContact SD-CD2 4.42Å; M134-W138 HydrophobicContact SD-CE3 3.51Å; M134-W138 VanDerWaalsContact SD-CE3 3.51Å; M134-W138 HydrophobicContact SD-CZ3 4Å; G136-W138 PolarHBondContact O-N 2.71Å; W138-L140 VanDerWaalsContact C-N 3.35Å; W138-L140 HydrophobicContact CD2-CB 3.99Å; W138-L140 HydrophobicContact CE3-CB 4.48Å; W138-L140 HydrophobicContact CE3-CD1 4.18Å; W138-L140 HydrophobicContact CH2-CB 4.18Å; W138-L140 HydrophobicContact CH2-CD1 3.67Å; W138-L140 HydrophobicContact CZ2-CB 3.61Å; W138-L140 HydrophobicContact CZ2-CD1 4Å; W138-L140 HydrophobicContact CZ2-CG 4.4Å; W138-L140 HydrophobicContact CZ3-CD1 3.78Å; W138-L140 PolarHBondContact O-N 2.89Å; W138-G141 PolarHBondContact NE1-O 3.22Å; W138-Y146 PolarHBondContact NE1-O 2.86Å; W138-P148 HydrophobicContact CB-CG 3.95Å; W138-P148 HydrophobicContact CD2-CG 3.65Å; W138-P148 HydrophobicContact CE3-CG 4.11Å; W138-P148 HydrophobicContact CG-CG 3.58Å; W138-R151 HydrophobicContact CH2-CB 4.17Å; W138-R151 HydrophobicContact CH2-CG 4.47Å; W138-R151 HydrophobicContact CZ2-CB 4.17Å; W138-R151 HydrophobicContact CZ2-CG 3.99Å; W138-F153 HydrophobicContact CZ3-CE2 4.03Å; W138-I159 PolarHBondContact N-O 3.37Å
139H98.6Very high98.1Very high2 Ų216.6 Ų16.61%0.00911%0.106CC..  trans60.432.3176.9-150.5178.8000115.5C84 S85 F106 K137 P160 S162C84-H139 VanDerWaalsContact CB-ND1 3.34Å; C84-H139 WeakPolarHBondContact CB-ND1 3.49Å; S85-H139 WeakPolarHBondContact CB-O 3.38Å; S85-H139 PolarHBondContact OG-CD2 2.88Å; S85-H139 PolarHBondContact OG-NE2 2.92Å; S85-H139 PolarHBondContact OG-O 3.4Å; F106-H139 PolarHBondContact O-NE2 2.9Å; K137-H139 WeakPolarHBondContact CE-ND1 3.34Å; K137-H139 HydrophobicContact CG-CB 4.11Å; H139-P160 WeakPolarHBondContact CA-O 3.47Å; H139-P160 PolarHBondContact N-O 3.22Å; H139-S162 PolarHBondContact CE1-OG 3.34Å
140L98.7Very high98.1Very high0 Ų020 Ų200%011%0.11CC..SBendtrans-12835.6177.7-67.8176000112.5S85 R88 A89 L92 V102 F106 G113 L114 W138S85-L140 VanDerWaalsContact O-CD2 3.29Å; S85-L140 WeakPolarHBondContact O-CD2 3.12Å; R88-L140 HydrophobicContact CB-CD1 4.26Å; R88-L140 HydrophobicContact CB-CD2 4.33Å; R88-L140 HydrophobicContact CB-CG 4.33Å; A89-L140 HydrophobicContact CB-CD2 3.71Å; L92-L140 HydrophobicContact CD1-CD1 3.66Å; V102-L140 HydrophobicContact CG1-CD2 4.44Å; F106-L140 HydrophobicContact CE2-CD2 4.44Å; G113-L140 CarbonylContact C-O 3.59Å; G113-L140 WeakPolarHBondContact CA-O 3.38Å; L114-L140 HydrophobicContact CB-CB 4.1Å; L114-L140 HydrophobicContact CD2-CD1 4.43Å; L114-L140 PolarHBondContact N-O 2.92Å; W138-L140 VanDerWaalsContact C-N 3.35Å; W138-L140 HydrophobicContact CD2-CB 3.99Å; W138-L140 HydrophobicContact CE3-CB 4.48Å; W138-L140 HydrophobicContact CE3-CD1 4.18Å; W138-L140 HydrophobicContact CH2-CB 4.18Å; W138-L140 HydrophobicContact CH2-CD1 3.67Å; W138-L140 HydrophobicContact CZ2-CB 3.61Å; W138-L140 HydrophobicContact CZ2-CD1 4Å; W138-L140 HydrophobicContact CZ2-CG 4.4Å; W138-L140 HydrophobicContact CZ3-CD1 3.78Å; W138-L140 PolarHBondContact O-N 2.89Å
141G97.3Very high98.1Very high2 Ų220.1 Ų20.12%0.02111%0.111CC..  trans82132.1-171.600000111.7G112 W138 Y146G112-G141 WeakPolarHBondContact O-CA 3.39Å; W138-G141 PolarHBondContact NE1-O 3.22Å; G141-Y146 CarbonylContact O-C 3.57Å; G141-Y146 WeakPolarHBondContact O-CB 3.46Å
142H95.3Very high98.1Very high11 Ų1119.2 Ų19.25%0.05111%0.107CC..  trans-109.9-16.5-171.858.9-75.1000113.5V108 P160 V509V108-H142 PolarHBondContact O-CE1 3.36Å; V108-H142 PolarHBondContact O-NE2 3.49Å; V108-H142 VanDerWaalsContact O-NE2 3.15Å; H142-P160 HydrophobicContact CB-CB 3.53Å; H142-V509 PolarHBondContact NE2-O 2.9Å
143H96.1Very high98.1Very high82 Ų8219.3 Ų19.338%0.3811%0.108SC..SBendtrans-81.9138-172.9-173.762000112.4S145 Y146 V509H143-S145 PolarHBondContact O-N 3.5Å; H143-Y146 WeakPolarHBondContact O-CB 3.23Å; H143-Y146 VanDerWaalsContact O-CD2 3.27Å; H143-Y146 WeakPolarHBondContact O-CD2 3.42Å; H143-Y146 PolarHBondContact O-N 3.22Å; H143-V509 HydrophobicContact CB-CB 4.13Å
144G95.7Very high98.1Very high40 Ų4022.7 Ų22.741%0.41213%0.125SC..G310 helixtrans50.3-127.3172.300000113.5Y146 H147 F150G144-Y146 PolarHBondContact O-N 3.44Å; G144-Y146 VanDerWaalsContact O-N 3.08Å; G144-H147 WeakPolarHBondContact O-CB 3.46Å; G144-H147 PolarHBondContact O-N 2.83Å; G144-H147 VanDerWaalsContact O-N 3.17Å; G144-F150 WeakPolarHBondContact O-CD2 3.44Å
145S97.3Very high98.1Very high65 Ų6524.6 Ų24.646%0.45513%0.133SC..G310 helixtrans-64.6-9.2-177.5-53.60000115.1L116 H143 H147 F150 R151L116-S145 WeakPolarHBondContact CD2-O 3.18Å; H143-S145 PolarHBondContact O-N 3.5Å; S145-H147 VanDerWaalsContact C-N 3.34Å; S145-F150 WeakPolarHBondContact O-CB 3.37Å; S145-R151 WeakPolarHBondContact O-CD 3.47Å
146Y98.3Very high98.1Very high40 Ų4024.6 Ų24.616%0.15713%0.133CC..G310 helixtrans-83.5-12176.6-58.3-72.4000112.9V111 G112 G113 L114 L116 W138 G141 H143 G144V111-Y146 WeakPolarHBondContact O-CE2 3.45Å; G112-Y146 VanDerWaalsContact CA-CE2 3.44Å; G113-Y146 VanDerWaalsContact CA-CD1 3.45Å; L114-Y146 VanDerWaalsContact O-CD1 3.26Å; L114-Y146 WeakPolarHBondContact O-CD1 3.16Å; L114-Y146 WeakPolarHBondContact O-CE1 3.33Å; L116-Y146 HydrophobicContact CD2-CD1 3.65Å; L116-Y146 HydrophobicContact CD2-CE1 3.62Å; L116-Y146 HydrophobicContact CD2-CG 4.37Å; L116-Y146 HydrophobicContact CG-CD1 4.29Å; L116-Y146 HydrophobicContact CG-CE1 3.72Å; W138-Y146 PolarHBondContact NE1-O 2.86Å; G141-Y146 CarbonylContact O-C 3.57Å; G141-Y146 WeakPolarHBondContact O-CB 3.46Å; H143-Y146 WeakPolarHBondContact O-CB 3.23Å; H143-Y146 VanDerWaalsContact O-CD2 3.27Å; H143-Y146 WeakPolarHBondContact O-CD2 3.42Å; H143-Y146 PolarHBondContact O-N 3.22Å; G144-Y146 PolarHBondContact O-N 3.44Å; G144-Y146 VanDerWaalsContact O-N 3.08Å
147H98.4Very high98.1Very high9 Ų925 Ų254%0.04214%0.135CC..SBendtrans-61.5142.7177.5-172.4-86000112.4G144 S145 N149 F150 Y156 Y204 N206G144-H147 WeakPolarHBondContact O-CB 3.46Å; G144-H147 PolarHBondContact O-N 2.83Å; G144-H147 VanDerWaalsContact O-N 3.17Å; S145-H147 VanDerWaalsContact C-N 3.34Å; H147-N149 VanDerWaalsContact C-N 3.27Å; H147-N149 PolarHBondContact CE1-OD1 2.72Å; H147-N149 PolarHBondContact ND1-N 2.6Å; H147-N149 PolarHBondContact ND1-OD1 2.97Å; H147-N149 PolarHBondContact O-N 2.66Å; H147-F150 HydrophobicContact CB-CD2 3.85Å; H147-F150 HydrophobicContact CB-CE2 4.2Å; H147-F150 PolarHBondContact O-N 3.29Å; H147-Y156 AromaticContact CE1-CD1 3.51Å; H147-Y156 AromaticContact NE2-CD1 3.66Å; H147-Y156 AromaticContact NE2-CE1 3.7Å; H147-Y204 AromaticContact NE2-CD1 3.72Å; H147-N206 PolarHBondContact CE1-O 2.66Å; H147-N206 PolarHBondContact NE2-O 2.9Å
148P98.6Very high98.1Very high1 Ų125 Ų251%0.00614%0.135CC..G310 helixtrans-49.3-40-174.5-31.334.7000115.7M134 W138 F150 R151 F153 Y156M134-P148 HydrophobicContact SD-CB 4.21Å; M134-P148 HydrophobicContact SD-CG 4.23Å; W138-P148 HydrophobicContact CB-CG 3.95Å; W138-P148 HydrophobicContact CD2-CG 3.65Å; W138-P148 HydrophobicContact CE3-CG 4.11Å; W138-P148 HydrophobicContact CG-CG 3.58Å; P148-F150 PolarHBondContact O-N 3.43Å; P148-R151 CarbonylContact O-C 3.43Å; P148-R151 WeakPolarHBondContact O-CA 3.49Å; P148-R151 PolarHBondContact O-N 3Å; P148-F153 HydrophobicContact CB-CD2 4.12Å; P148-F153 PolarHBondContact O-N 3Å; P148-Y156 HydrophobicContact CB-CD1 4.33Å; P148-Y156 HydrophobicContact CB-CD2 4.01Å; P148-Y156 HydrophobicContact CB-CE2 4.48Å; P148-Y156 HydrophobicContact CB-CG 3.92Å; P148-Y156 HydrophobicContact CG-CD1 4.04Å; P148-Y156 HydrophobicContact CG-CD2 3.9Å; P148-Y156 HydrophobicContact CG-CE1 3.99Å; P148-Y156 HydrophobicContact CG-CE2 3.89Å; P148-Y156 HydrophobicContact CG-CG 3.98Å
149N98.3Very high98.1Very high34 Ų3424.9 Ų24.918%0.18213%0.134CC..G310 helixtrans-64.3-20.8179.3-66.7112.4000114.4H147 F153 N206 L207H147-N149 VanDerWaalsContact C-N 3.27Å; H147-N149 PolarHBondContact CE1-OD1 2.72Å; H147-N149 PolarHBondContact ND1-N 2.6Å; H147-N149 PolarHBondContact ND1-OD1 2.97Å; H147-N149 PolarHBondContact O-N 2.66Å; N149-F153 WeakPolarHBondContact CA-O 3.48Å; N149-F153 PolarHBondContact ND2-O 3.31Å; N149-N206 PolarHBondContact ND2-OD1 3.39Å; N149-N206 VanDerWaalsContact OD1-CA 3.23Å; N149-N206 WeakPolarHBondContact OD1-CA 3.21Å; N149-L207 HydrophobicContact CB-CD2 4.11Å
150F98.4Very high98Very high107 Ų10725 Ų2547%0.46914%0.135SC..G310 helixtrans-95.53.7173-55-61.9000112.7G144 S145 H147 P148 L207G144-F150 WeakPolarHBondContact O-CD2 3.44Å; S145-F150 WeakPolarHBondContact O-CB 3.37Å; H147-F150 HydrophobicContact CB-CD2 3.85Å; H147-F150 HydrophobicContact CB-CE2 4.2Å; H147-F150 PolarHBondContact O-N 3.29Å; P148-F150 PolarHBondContact O-N 3.43Å; F150-L207 HydrophobicContact CE2-CD2 3.85Å; F150-L207 HydrophobicContact CZ-CD1 4.15Å; F150-L207 HydrophobicContact CZ-CD2 3.93Å
151R98.4Very high98Very high5 Ų525.1 Ų25.12%0.01914%0.135CC..THydrogen-bonded Turntrans-119.829.8-178.4-53.6-59.5-67.1146.3-3.1111.5P115 E118 T120 E123 W138 S145 P148P115-R151 PolarHBondContact O-NH2 2.78Å; P115-R151 VanDerWaalsContact O-NH2 3.13Å; E118-R151 PolarHBondContact O-NH2 3.46Å; T120-R151 HydrophobicContact CG2-CB 4.13Å; T120-R151 PolarHBondContact OG1-O 3.4Å; E123-R151 IonicContact OE1-NH1 2.74Å; W138-R151 HydrophobicContact CH2-CB 4.17Å; W138-R151 HydrophobicContact CH2-CG 4.47Å; W138-R151 HydrophobicContact CZ2-CB 4.17Å; W138-R151 HydrophobicContact CZ2-CG 3.99Å; S145-R151 WeakPolarHBondContact O-CD 3.47Å; P148-R151 CarbonylContact O-C 3.43Å; P148-R151 WeakPolarHBondContact O-CA 3.49Å; P148-R151 PolarHBondContact O-N 3Å
152G98.4Very high98Very high4 Ų425.1 Ų25.14%0.04114%0.135CC..THydrogen-bonded Turntrans95.41.6170.600000116.4A122 T132A122-G152 WeakPolarHBondContact CB-O 3.4Å; T132-G152 WeakPolarHBondContact CB-O 3.37Å; T132-G152 PolarHBondContact OG1-O 2.7Å
153F98.8Very high98Very high2 Ų225 Ų251%0.00913%0.134CC..  trans-94117.3178-66.8-75.1000112.3L92 A122 T132 M134 W138 P148 N149 Y155 L242 Y244L92-F153 HydrophobicContact CD2-CZ 4.3Å; A122-F153 HydrophobicContact CB-CD1 3.81Å; A122-F153 HydrophobicContact CB-CD2 4.04Å; A122-F153 HydrophobicContact CB-CE1 3.62Å; A122-F153 HydrophobicContact CB-CE2 3.85Å; A122-F153 HydrophobicContact CB-CG 4.03Å; A122-F153 HydrophobicContact CB-CZ 3.65Å; T132-F153 WeakPolarHBondContact OG1-CA 3.45Å; M134-F153 HydrophobicContact CB-CB 4.37Å; M134-F153 HydrophobicContact CB-CD1 3.64Å; M134-F153 HydrophobicContact CB-CD2 4.12Å; M134-F153 HydrophobicContact CB-CE1 3.83Å; M134-F153 HydrophobicContact CB-CE2 4.3Å; M134-F153 HydrophobicContact CB-CG 3.78Å; M134-F153 HydrophobicContact CB-CZ 4.15Å; M134-F153 HydrophobicContact SD-CD2 4.32Å; M134-F153 HydrophobicContact SD-CE2 4.02Å; M134-F153 HydrophobicContact SD-CZ 4.33Å; W138-F153 HydrophobicContact CZ3-CE2 4.03Å; P148-F153 HydrophobicContact CB-CD2 4.12Å; P148-F153 PolarHBondContact O-N 3Å; N149-F153 WeakPolarHBondContact CA-O 3.48Å; N149-F153 PolarHBondContact ND2-O 3.31Å; F153-Y155 VanDerWaalsContact C-N 3.29Å; F153-Y155 PolarHBondContact O-N 3.13Å; F153-L242 HydrophobicContact CE1-CD2 4.2Å; F153-Y244 HydrophobicContact CE1-CD1 4.39Å; F153-Y244 AromaticContact CZ-CD1 3.8Å; F153-Y244 HydrophobicContact CZ-CD1 3.8Å; F153-Y244 HydrophobicContact CZ-CG 4.36Å
154D98.7Very high98Very high70 Ų7022.7 Ų22.737%0.37413%0.125SC..SBendtrans-66.2-34.1176-57.3-44.4000111.8Q126 I131 T132Q126-D154 PolarHBondContact NE2-OD1 3.05Å; I131-D154 WeakPolarHBondContact CA-OD2 3.17Å; T132-D154 PolarHBondContact N-OD2 2.98Å; T132-D154 WeakPolarHBondContact O-CA 3.39Å; T132-D154 WeakPolarHBondContact O-CB 3.39Å; T132-D154 PolarHBondContact O-N 3.08Å; T132-D154 PolarHBondContact OG1-N 2.9Å; T132-D154 PolarHBondContact OG1-OD2 3.24Å
155Y98.9Very high97.9Very high41 Ų4121.5 Ų21.516%0.16111%0.109CC..EExtended strand (participates in β ladder)trans-127.5136.6178.3-177.7-112.4000111.6T132 G133 M134 I135 F153 F157 E205 N206 K226 F230T132-Y155 PolarHBondContact O-N 3.23Å; G133-Y155 CarbonylContact C-O 3.54Å; G133-Y155 WeakPolarHBondContact CA-O 3.27Å; M134-Y155 PolarHBondContact N-O 3.46Å; I135-Y155 HydrophobicContact CD1-CD1 4.07Å; I135-Y155 HydrophobicContact CD1-CE1 3.63Å; F153-Y155 VanDerWaalsContact C-N 3.29Å; F153-Y155 PolarHBondContact O-N 3.13Å; Y155-F157 HydrophobicContact CE1-CB 3.99Å; Y155-E205 HydrophobicContact CE2-CG 4.12Å; Y155-E205 WeakPolarHBondContact CE2-OE1 3.43Å; Y155-E205 PolarHBondContact OH-OE1 2.74Å; Y155-N206 WeakPolarHBondContact CA-OD1 3.46Å; Y155-K226 WeakPolarHBondContact OH-CD 3.46Å; Y155-F230 HydrophobicContact CD1-CD2 4.07Å; Y155-F230 HydrophobicContact CG-CD2 4.48Å
156Y98.9Very high97.8Very high0 Ų018.7 Ų18.70%09%0.09CC..EExtended strand (participates in β ladder)trans-133.7133.8172.7174.2-124.8000111.2M134 G136 H147 P148 G158 I159 Y204 E205 N206M134-Y156 HydrophobicContact CB-CD2 4.06Å; M134-Y156 HydrophobicContact CE-CE2 4.3Å; M134-Y156 HydrophobicContact CG-CD2 3.93Å; M134-Y156 HydrophobicContact CG-CE2 4.23Å; M134-Y156 WeakPolarHBondContact O-CA 3.17Å; M134-Y156 HydrophobicContact SD-CD2 4.27Å; M134-Y156 HydrophobicContact SD-CE2 4.28Å; G136-Y156 WeakPolarHBondContact O-CE2 3.24Å; H147-Y156 AromaticContact CE1-CD1 3.51Å; H147-Y156 AromaticContact NE2-CD1 3.66Å; H147-Y156 AromaticContact NE2-CE1 3.7Å; P148-Y156 HydrophobicContact CB-CD1 4.33Å; P148-Y156 HydrophobicContact CB-CD2 4.01Å; P148-Y156 HydrophobicContact CB-CE2 4.48Å; P148-Y156 HydrophobicContact CB-CG 3.92Å; P148-Y156 HydrophobicContact CG-CD1 4.04Å; P148-Y156 HydrophobicContact CG-CD2 3.9Å; P148-Y156 HydrophobicContact CG-CE1 3.99Å; P148-Y156 HydrophobicContact CG-CE2 3.89Å; P148-Y156 HydrophobicContact CG-CG 3.98Å; Y156-G158 PolarHBondContact OH-O 3.28Å; Y156-I159 PolarHBondContact OH-N 3.07Å; Y156-I159 PolarHBondContact OH-O 3.08Å; Y156-Y204 HydrophobicContact CE1-CG 4.19Å; Y156-E205 CarbonylContact O-C 3.58Å; Y156-E205 WeakPolarHBondContact O-CA 3.43Å; Y156-N206 PolarHBondContact N-OD1 3.12Å; Y156-N206 PolarHBondContact O-N 3.32Å
157F98.9Very high97.6Very high8 Ų817.1 Ų17.14%0.0359%0.085CC..EExtended strand (participates in β ladder)trans-140.8113.7166.6-179.8-91.3000109.8M134 I135 G136 Y155 L203 Y204 E205 V210 K222 Y223 K226M134-F157 PolarHBondContact O-N 2.88Å; I135-F157 CarbonylContact C-O 3.47Å; I135-F157 VanDerWaalsContact CA-O 3.26Å; I135-F157 WeakPolarHBondContact CA-O 3.21Å; I135-F157 HydrophobicContact CD1-CB 3.87Å; G136-F157 PolarHBondContact N-O 2.79Å; Y155-F157 HydrophobicContact CE1-CB 3.99Å; F157-L203 HydrophobicContact CE1-CD1 4.12Å; F157-L203 HydrophobicContact CE1-CD2 4.31Å; F157-L203 HydrophobicContact CE2-CD2 4.24Å; F157-L203 HydrophobicContact CE2-CG 4.37Å; F157-L203 HydrophobicContact CZ-CD1 4.18Å; F157-L203 HydrophobicContact CZ-CD2 3.7Å; F157-L203 HydrophobicContact CZ-CG 4.14Å; F157-Y204 VanDerWaalsContact CA-O 3.29Å; F157-Y204 WeakPolarHBondContact CA-O 3.41Å; F157-E205 HydrophobicContact CD2-CB 3.97Å; F157-E205 HydrophobicContact CD2-CG 4.21Å; F157-V210 HydrophobicContact CE2-CG2 4.4Å; F157-K222 HydrophobicContact CE1-CB 3.89Å; F157-K222 HydrophobicContact CZ-CB 4.02Å; F157-K222 HydrophobicContact CZ-CD 4.5Å; F157-Y223 AromaticContact CD1-CD1 3.82Å; F157-Y223 HydrophobicContact CD1-CD1 3.82Å; F157-Y223 AromaticContact CD1-CE1 4Å; F157-Y223 HydrophobicContact CD1-CE1 4Å; F157-Y223 AromaticContact CE1-CD1 3.78Å; F157-Y223 HydrophobicContact CE1-CD1 3.78Å; F157-Y223 AromaticContact CE1-CE1 3.98Å; F157-Y223 HydrophobicContact CE1-CE1 3.98Å; F157-K226 HydrophobicContact CB-CB 4.41Å; F157-K226 HydrophobicContact CB-CG 4.33Å; F157-K226 HydrophobicContact CD1-CB 4.08Å; F157-K226 HydrophobicContact CD1-CG 3.67Å; F157-K226 HydrophobicContact CD2-CD 4.35Å; F157-K226 HydrophobicContact CD2-CG 4.01Å; F157-K226 HydrophobicContact CE1-CG 3.86Å; F157-K226 HydrophobicContact CE2-CG 4.18Å; F157-K226 HydrophobicContact CG-CB 4.25Å; F157-K226 HydrophobicContact CG-CD 4.46Å; F157-K226 HydrophobicContact CG-CG 3.74Å; F157-K226 HydrophobicContact CZ-CG 4.09Å
158G98.7Very high97.4Very high0 Ų016.9 Ų16.90%08%0.084CC..EExtended strand (participates in β ladder)trans166.9-176.5-174.400000116G136 Y156 Y204G136-G158 WeakPolarHBondContact O-CA 3.48Å; Y156-G158 PolarHBondContact OH-O 3.28Å; G158-Y204 PolarHBondContact N-O 3.22Å; G158-Y204 PolarHBondContact O-N 3.03Å
159I98.7Very high97.1Very high0 Ų020 Ų200%010%0.101CC..  trans-94.8137.1179.359.7178.5000110.3G136 K137 W138 Y156 Y161 H163 L201 L203 V214 A248G136-I159 PolarHBondContact O-N 3.17Å; K137-I159 WeakPolarHBondContact CA-O 3.47Å; K137-I159 HydrophobicContact CB-CD1 4.34Å; K137-I159 HydrophobicContact CB-CG1 4.02Å; W138-I159 PolarHBondContact N-O 3.37Å; Y156-I159 PolarHBondContact OH-N 3.07Å; Y156-I159 PolarHBondContact OH-O 3.08Å; I159-Y161 VanDerWaalsContact C-N 3.27Å; I159-Y161 VanDerWaalsContact CD1-O 3.3Å; I159-Y161 WeakPolarHBondContact CD1-O 3.47Å; I159-Y161 VanDerWaalsContact CG1-O 3.32Å; I159-Y161 WeakPolarHBondContact CG1-O 3.46Å; I159-Y161 PolarHBondContact O-N 2.72Å; I159-H163 HydrophobicContact CD1-CB 3.69Å; I159-L201 HydrophobicContact CB-CD1 4.49Å; I159-L201 HydrophobicContact CG2-CD2 4.16Å; I159-L201 HydrophobicContact CG2-CG 4.29Å; I159-L203 HydrophobicContact CG2-CD1 4.25Å; I159-V214 HydrophobicContact CG2-CG2 4.21Å; I159-A248 HydrophobicContact CD1-CB 4.11Å
160P98.1Very high96.6Very high3 Ų321 Ų212%0.01911%0.108CC..SBendtrans-69.8-21.9-17425.2-33.4000114.3H139 H142 P202 Y204H139-P160 WeakPolarHBondContact CA-O 3.47Å; H139-P160 PolarHBondContact N-O 3.22Å; H142-P160 HydrophobicContact CB-CB 3.53Å; P160-P202 WeakPolarHBondContact CD-O 3.36Å; P160-P202 HydrophobicContact CG-CG 3.7Å; P160-Y204 HydrophobicContact CB-CE2 4.43Å; P160-Y204 HydrophobicContact CG-CD2 4.33Å; P160-Y204 HydrophobicContact CG-CE2 3.98Å
161Y97.8Very high96Very high3 Ų317.3 Ų17.31%0.01210%0.095CC..SBendtrans-150.7-177.7-175.836.8-111.6000109.8V108 I159 M165 L201 P202 P511V108-Y161 HydrophobicContact CB-CD1 4.49Å; V108-Y161 HydrophobicContact CB-CE1 3.97Å; V108-Y161 HydrophobicContact CG1-CD1 4.16Å; V108-Y161 HydrophobicContact CG1-CD2 4.07Å; V108-Y161 HydrophobicContact CG1-CE1 3.89Å; V108-Y161 HydrophobicContact CG1-CE2 3.76Å; V108-Y161 HydrophobicContact CG1-CG 4.25Å; I159-Y161 VanDerWaalsContact C-N 3.27Å; I159-Y161 VanDerWaalsContact CD1-O 3.3Å; I159-Y161 WeakPolarHBondContact CD1-O 3.47Å; I159-Y161 VanDerWaalsContact CG1-O 3.32Å; I159-Y161 WeakPolarHBondContact CG1-O 3.46Å; I159-Y161 PolarHBondContact O-N 2.72Å; Y161-M165 HydrophobicContact CD2-CB 3.72Å; Y161-M165 HydrophobicContact CE2-CB 4.17Å; Y161-M165 WeakPolarHBondContact CE2-O 3.18Å; Y161-M165 HydrophobicContact CG-CB 4.4Å; Y161-L201 HydrophobicContact CD2-CD1 3.95Å; Y161-L201 HydrophobicContact CE2-CD1 3.62Å; Y161-P202 WeakPolarHBondContact OH-CD 3.45Å; Y161-P511 HydrophobicContact CE1-CG 4.18Å
162S97.4Very high95.6Very high2 Ų218 Ų181%0.01410%0.103CC..  trans-56.7143.6178.3-55.80000111.5K137 H139 D164 M165K137-S162 WeakPolarHBondContact CE-OG 3.19Å; K137-S162 PolarHBondContact NZ-OG 3.44Å; H139-S162 PolarHBondContact CE1-OG 3.34Å; S162-D164 WeakPolarHBondContact CB-OD1 3.4Å; S162-D164 PolarHBondContact O-N 3.11Å; S162-M165 VanDerWaalsContact O-CB 3.31Å; S162-M165 WeakPolarHBondContact O-CB 3.11Å; S162-M165 PolarHBondContact O-N 2.8Å
163H95.8Very high95.3Very high8 Ų821.6 Ų21.64%0.03712%0.116CC..THydrogen-bonded Turntrans-75.5-3.9-175.959.6-74.5000114.8I159 M165 L201 L216 A248 H251 V252 P253I159-H163 HydrophobicContact CD1-CB 3.69Å; H163-M165 VanDerWaalsContact C-N 3.34Å; H163-L201 HydrophobicContact CB-CD2 3.41Å; H163-L201 VanDerWaalsContact CB-CD2 3.41Å; H163-L216 HydrophobicContact CB-CD2 4.07Å; H163-A248 PolarHBondContact CE1-O 2.84Å; H163-H251 PolarHBondContact CE1-O 2.93Å; H163-H251 PolarHBondContact NE2-O 2.81Å; H163-V252 PolarHBondContact NE2-O 3.09Å; H163-P253 VanDerWaalsContact CD2-CD 3.44Å; H163-P253 WeakPolarHBondContact CD2-CD 3.47Å; H163-P253 PolarHBondContact CD2-O 3.12Å; H163-P253 PolarHBondContact NE2-O 2.88Å
164D94.8Very high95Very high34 Ų3422.1 Ų22.118%0.18212%0.119CC..THydrogen-bonded Turntrans-83.2-11.316566.3-35.5000113S162 G166 Y196 H251S162-D164 WeakPolarHBondContact CB-OD1 3.4Å; S162-D164 PolarHBondContact O-N 3.11Å; D164-G166 PolarHBondContact O-N 2.84Å; D164-G166 VanDerWaalsContact O-N 3.12Å; D164-Y196 VanDerWaalsContact O-CD2 3.26Å; D164-Y196 WeakPolarHBondContact O-CD2 3.37Å; D164-H251 VanDerWaalsContact CG-CE1 3.5Å; D164-H251 IonicContact OD1-CE1 3.17Å; D164-H251 PolarHBondContact OD1-CE1 3.27Å; D164-H251 VanDerWaalsContact OD1-CE1 3.23Å; D164-H251 IonicContact OD1-ND1 3.07Å; D164-H251 IonicContact OD2-CE1 3.54Å
165M95.2Very high94.7Very high15 Ų1522.8 Ų22.87%0.07412%0.12CC..SBendtrans-87.341.4179-56.3175.367.300112F106 V108 Y161 S162 H163 Y196F106-M165 VanDerWaalsContact O-CE 3.32Å; F106-M165 WeakPolarHBondContact O-CE 3.33Å; V108-M165 HydrophobicContact CG1-CB 3.67Å; V108-M165 HydrophobicContact CG1-CE 3.95Å; V108-M165 WeakPolarHBondContact CG1-O 3.49Å; Y161-M165 HydrophobicContact CD2-CB 3.72Å; Y161-M165 HydrophobicContact CE2-CB 4.17Å; Y161-M165 WeakPolarHBondContact CE2-O 3.18Å; Y161-M165 HydrophobicContact CG-CB 4.4Å; S162-M165 VanDerWaalsContact O-CB 3.31Å; S162-M165 WeakPolarHBondContact O-CB 3.11Å; S162-M165 PolarHBondContact O-N 2.8Å; H163-M165 VanDerWaalsContact C-N 3.34Å; M165-Y196 HydrophobicContact CB-CD2 4.39Å; M165-Y196 HydrophobicContact CB-CE1 4.46Å; M165-Y196 HydrophobicContact CB-CE2 4.14Å; M165-Y196 HydrophobicContact CG-CE2 4.04Å
166G94.3Very high94.3Very high6 Ų622.9 Ų22.96%0.06213%0.125CC..SBendtrans173.7147.2176.800000109.9D164 Y196 V199D164-G166 PolarHBondContact O-N 2.84Å; D164-G166 VanDerWaalsContact O-N 3.12Å; G166-Y196 CarbonylContact C-O 3.46Å; G166-V199 CarbonylContact C-O 3.5Å; G166-V199 WeakPolarHBondContact CA-O 3.18Å
167C94Very high93.9Very high7 Ų726.8 Ų26.85%0.04715%0.151CC..BIsolated β-bridgetrans-71.4157.9176.668.40000110.3C181 Y196 V199 A200 L201C167-C181 HydrophobicContact CB-CB 3.94Å; C167-C181 WeakPolarHBondContact CB-SG 3.48Å; C167-C181 PolarHBondContact O-SG 2.92Å; C167-C181 WeakPolarHBondContact SG-CA 3.31Å; C167-C181 WeakPolarHBondContact SG-CB 3.36Å; C167-C181 CovalentContact SG-SG 2.04Å; C167-C181 PolarHBondContact SG-SG 3.21Å; C167-Y196 WeakPolarHBondContact CA-O 3.48Å; C167-Y196 VanDerWaalsContact CB-O 3.27Å; C167-Y196 WeakPolarHBondContact CB-O 3.3Å; C167-Y196 PolarHBondContact N-O 3.13Å; C167-V199 PolarHBondContact N-O 3.35Å; C167-A200 WeakPolarHBondContact O-CA 3.4Å; C167-L201 PolarHBondContact O-N 2.88Å
168T93.8Very high93.4Very high4 Ų428 Ų283%0.02516%0.16CC..  trans-134.6162.8165.667.70000110T170 P171 A180 C181 L201 V214 L216T168-T170 PolarHBondContact O-N 3.41Å; T168-T170 VanDerWaalsContact OG1-C 3.32Å; T168-T170 PolarHBondContact OG1-O 3.27Å; T168-P171 WeakPolarHBondContact OG1-CA 3.31Å; T168-A180 CarbonylContact O-C 3.59Å; T168-A180 VanDerWaalsContact O-CA 3.26Å; T168-A180 WeakPolarHBondContact O-CA 3.46Å; T168-C181 PolarHBondContact N-SG 2.88Å; T168-C181 VanDerWaalsContact N-SG 3.38Å; T168-C181 PolarHBondContact O-N 3.49Å; T168-L201 HydrophobicContact CG2-CB 4.12Å; T168-L201 HydrophobicContact CG2-CD2 4.33Å; T168-V214 WeakPolarHBondContact CB-O 3.49Å; T168-V214 WeakPolarHBondContact CG2-O 3.49Å; T168-L216 HydrophobicContact CG2-CD1 4.14Å; T168-L216 HydrophobicContact CG2-CD2 4.25Å; T168-L216 HydrophobicContact CG2-CG 3.99Å
169D92.1Very high93Very high67 Ų6731 Ų3136%0.35818%0.179SC..SBendtrans-71.7-22.1177.3-67.9-23.6000113.1P171 Q183 P213 R521D169-P171 WeakPolarHBondContact O-CD 3.26Å; D169-Q183 PolarHBondContact OD1-NE2 3.06Å; D169-Q183 VanDerWaalsContact OD1-NE2 3.07Å; D169-P213 WeakPolarHBondContact OD2-CG 3.27Å; D169-R521 IonicContact OD1-CZ 2.6Å; D169-R521 IonicContact OD1-NH2 3.91Å; D169-R521 PolarHBondContact OD1-NH2 3.15Å; D169-R521 IonicContact OD2-CZ 2.65Å; D169-R521 IonicContact OD2-NH2 3.78Å; D169-R521 PolarHBondContact OD2-NH2 3.45Å
170T88.6Confident92.7Very high55 Ų5533.1 Ų33.134%0.33720%0.197SC..SBendtrans-124.174.1178.448.20000107.9T168 G172T168-T170 PolarHBondContact O-N 3.41Å; T168-T170 VanDerWaalsContact OG1-C 3.32Å; T168-T170 PolarHBondContact OG1-O 3.27Å; T170-G172 PolarHBondContact O-N 3.19Å
171P85.4Confident92.3Very high30 Ų3033.2 Ų33.220%0.19520%0.198CC..  trans-6410.3-164.827.4-38.4000116.4T168 D169 C178 A180 P253T168-P171 WeakPolarHBondContact OG1-CA 3.31Å; D169-P171 WeakPolarHBondContact O-CD 3.26Å; P171-C178 WeakPolarHBondContact CB-O 3.15Å; P171-C178 WeakPolarHBondContact CG-O 3.2Å; P171-A180 HydrophobicContact CG-CB 4.24Å; P171-P253 WeakPolarHBondContact O-CB 3.39Å
172G90.3Very high91.9Very high18 Ų1834.8 Ų34.819%0.18621%0.208CC..  trans58.7-163.4177.600000113.1T170 L254T170-G172 PolarHBondContact O-N 3.19Å; G172-L254 CarbonylContact C-O 3.57Å; G172-L254 WeakPolarHBondContact CA-O 3.28Å
173Y92.3Very high91.2Very high80 Ų8039 Ų3931%0.31423%0.228SC..BIsolated β-bridgetrans-99.1120.4174.3-61.4-74.8000109.8P253 L254 V256 L268Y173-P253 CarbonylContact O-C 3.52Å; Y173-P253 WeakPolarHBondContact O-CA 3.33Å; Y173-L254 PolarHBondContact N-O 3.17Å; Y173-L254 PolarHBondContact O-N 3.34Å; Y173-V256 HydrophobicContact CE2-CB 4.39Å; Y173-V256 HydrophobicContact CE2-CG1 4.34Å; Y173-V256 HydrophobicContact CE2-CG2 4.19Å; Y173-L268 HydrophobicContact CD1-CD1 3.9Å; Y173-L268 HydrophobicContact CD2-CD1 4.17Å; Y173-L268 HydrophobicContact CD2-CD2 3.7Å; Y173-L268 HydrophobicContact CD2-CG 4.47Å; Y173-L268 HydrophobicContact CE1-CD1 4.25Å; Y173-L268 HydrophobicContact CE1-CD2 4.39Å; Y173-L268 HydrophobicContact CE2-CD1 4.47Å; Y173-L268 HydrophobicContact CE2-CD2 3.47Å; Y173-L268 VanDerWaalsContact CE2-CD2 3.47Å; Y173-L268 HydrophobicContact CG-CD1 3.85Å; Y173-L268 HydrophobicContact CG-CD2 4.24Å
174N92.9Very high90.2Very high14 Ų1440.4 Ų40.48%0.07524%0.244CC..  trans-133162.3174.6-164.411.3000110.4P176 P177 C178 V252 P253 K309 L312N174-P176 CarbonylContact C-O 3.48Å; N174-P176 VanDerWaalsContact C-O 3.29Å; N174-P176 WeakPolarHBondContact CB-O 3.41Å; N174-P176 PolarHBondContact ND2-O 3.08Å; N174-P176 CarbonylContact O-C 3.3Å; N174-P176 VanDerWaalsContact O-C 3.3Å; N174-P177 WeakPolarHBondContact O-CA 3.39Å; N174-C178 PolarHBondContact ND2-SG 3.29Å; N174-C178 VanDerWaalsContact ND2-SG 3.38Å; N174-V252 WeakPolarHBondContact OD1-CG2 3.43Å; N174-P253 HydrophobicContact CB-CB 4.21Å; N174-K309 PolarHBondContact OD1-NZ 3.3Å; N174-L312 VanDerWaalsContact C-CD1 3.4Å
175H90.9Very high88.7Confident83 Ų8346.3 Ų46.338%0.38428%0.276SS..SBendtrans-126.3115.9171-170.576.1000110.3K309 C310 L312H175-K309 VanDerWaalsContact O-CD 3.24Å; H175-K309 WeakPolarHBondContact O-CD 3.42Å; H175-K309 PolarHBondContact O-NZ 3.4Å; H175-C310 PolarHBondContact CD2-SG 2.96Å; H175-L312 HydrophobicContact CB-CD1 4.23Å
176P90.8Very high86.9Confident43 Ų4348.1 Ų48.128%0.27930%0.298SS..SBendcis-60.8159.7-13.729.6-35.6000111.9N174N174-P176 CarbonylContact C-O 3.48Å; N174-P176 VanDerWaalsContact C-O 3.29Å; N174-P176 WeakPolarHBondContact CB-O 3.41Å; N174-P176 PolarHBondContact ND2-O 3.08Å; N174-P176 CarbonylContact O-C 3.3Å; N174-P176 VanDerWaalsContact O-C 3.3Å
177P90.3Very high84.8Confident83 Ų8353.9 Ų53.954%0.53933%0.334SS..PPolyproline II helixtrans-61.2140.3175.3-22.133.3000111.2N174 Q192N174-P177 WeakPolarHBondContact O-CA 3.39Å; P177-Q192 PolarHBondContact O-NE2 2.94Å; P177-Q192 PolarHBondContact O-OE1 2.75Å
178C89.8Confident82.9Confident32 Ų3255.8 Ų55.822%0.21635%0.348CS..PPolyproline II helixtrans-100148.5173.5-71.20000111.4P171 N174 C195P171-C178 WeakPolarHBondContact CB-O 3.15Å; P171-C178 WeakPolarHBondContact CG-O 3.2Å; N174-C178 PolarHBondContact ND2-SG 3.29Å; N174-C178 VanDerWaalsContact ND2-SG 3.38Å; C178-C195 WeakPolarHBondContact CA-SG 3.15Å; C178-C195 HydrophobicContact CB-CB 3.82Å; C178-C195 WeakPolarHBondContact CB-SG 3.43Å; C178-C195 WeakPolarHBondContact SG-CB 3.31Å; C178-C195 CovalentContact SG-SG 2.05Å; C178-C195 PolarHBondContact SG-SG 2.87Å
179P90.5Very high80.8Confident63 Ų6359.5 Ų59.541%0.40937%0.374SS..PPolyproline II helixtrans-72.1163.7175.531.8-35.7000111.9T197P179-T197 HydrophobicContact CG-CG2 3.9Å
180A91.3Very high78.8Confident46 Ų4663.1 Ų63.138%0.3839%0.393SS..PPolyproline II helixtrans-69.2163.8170.900000111.2T168 P171T168-A180 CarbonylContact O-C 3.59Å; T168-A180 VanDerWaalsContact O-CA 3.26Å; T168-A180 WeakPolarHBondContact O-CA 3.46Å; P171-A180 HydrophobicContact CG-CB 4.24Å
181C90.6Very high77Confident5 Ų567.4 Ų67.43%0.03441%0.413CS..PPolyproline II helixtrans-55.1141174.1-78.80000112.2C167 T168 Q183C167-C181 HydrophobicContact CB-CB 3.94Å; C167-C181 WeakPolarHBondContact CB-SG 3.48Å; C167-C181 PolarHBondContact O-SG 2.92Å; C167-C181 WeakPolarHBondContact SG-CA 3.31Å; C167-C181 WeakPolarHBondContact SG-CB 3.36Å; C167-C181 CovalentContact SG-SG 2.04Å; C167-C181 PolarHBondContact SG-SG 3.21Å; T168-C181 PolarHBondContact N-SG 2.88Å; T168-C181 VanDerWaalsContact N-SG 3.38Å; T168-C181 PolarHBondContact O-N 3.49Å; C181-Q183 PolarHBondContact O-NE2 2.68Å
182P88.4Confident75.6Confident35 Ų3569.6 Ų69.623%0.22742%0.421CS..PPolyproline II helixtrans-62.3140.6173.326.8-33.4000110.7T197 T518 A519P182-T197 VanDerWaalsContact CD-O 3.22Å; P182-T197 WeakPolarHBondContact CD-O 3.47Å; P182-T197 WeakPolarHBondContact CG-O 3.34Å; P182-T518 HydrophobicContact CB-CG2 4.06Å; P182-T518 HydrophobicContact CG-CG2 3.92Å; P182-A519 HydrophobicContact CG-CB 4.15Å
183Q83.6Confident74.1Confident92 Ų9280.1 Ų80.143%0.4346%0.455SS..  trans-106.5-0.1-178.1-58.4-64.2-2600113.1D169 C181 P525D169-Q183 PolarHBondContact OD1-NE2 3.06Å; D169-Q183 VanDerWaalsContact OD1-NE2 3.07Å; C181-Q183 PolarHBondContact O-NE2 2.68Å; Q183-P525 HydrophobicContact CB-CG 4.45Å; Q183-P525 VanDerWaalsContact OE1-CG 3.24Å
184G75.3Confident73.2Confident36 Ų3682.3 Ų82.337%0.37147%0.472SS..SBendtrans-166.9177.8178.800000112.8G186G184-G186 PolarHBondContact O-N 2.93Å
185D63.3Low72.8Confident159 Ų15982.5 Ų82.585%0.8548%0.475SS*.SBendtrans-75.119.6-168.8-57.6-36.4000115.4T518D185-T518 PolarHBondContact OD1-OG1 2.63Å
186G56.7Low72.5Confident52 Ų5283 Ų8354%0.53647%0.473SS..SBendtrans-70.1145.6174.700000111G184 S188G184-G186 PolarHBondContact O-N 2.93Å; G186-S188 PolarHBondContact O-N 3.11Å; G186-S188 VanDerWaalsContact O-N 3.1Å
187P49.4Very low72.2Confident127 Ų12781.8 Ų81.883%0.82547%0.465SS*.  trans-57122.9173.222.8-30.4000108.9S189P187-S189 VanDerWaalsContact C-N 3.31Å; P187-S189 PolarHBondContact O-N 3.35Å
188S53.7Low71.9Confident48 Ų4883.8 Ų83.834%0.33647%0.472SS..  trans-56.5102.2164179.10000106G186 N190 T197G186-S188 PolarHBondContact O-N 3.11Å; G186-S188 VanDerWaalsContact O-N 3.1Å; S188-N190 PolarHBondContact O-N 2.72Å; S188-T197 PolarHBondContact OG-OG1 3.09Å; S188-T197 VanDerWaalsContact OG-OG1 3.13Å
189S50.8Low72Confident81 Ų8182.9 Ų82.957%0.56647%0.465SS*.  trans-62.6107.2172.957.20000105.5P187 L191P187-S189 VanDerWaalsContact C-N 3.31Å; P187-S189 PolarHBondContact O-N 3.35Å; S189-L191 PolarHBondContact O-N 2.8Å; S189-L191 VanDerWaalsContact OG-CD1 3.29Å; S189-L191 WeakPolarHBondContact OG-CD1 3.49Å
190N50Low72.2Confident143 Ų14379.9 Ų79.977%0.76545%0.446SS*.  trans-56.461.6177.2-81.1-35.8000112.3S188S188-N190 PolarHBondContact O-N 2.72Å
191L50Low72.5Confident146 Ų14677.7 Ų77.776%0.76443%0.428SS*.  trans-86.1-18.2-173.9-77.7166.5000111.8S189S189-L191 PolarHBondContact O-N 2.8Å; S189-L191 VanDerWaalsContact OG-CD1 3.29Å; S189-L191 WeakPolarHBondContact OG-CD1 3.49Å
192Q57.6Low72.9Confident75 Ų7577.5 Ų77.535%0.3543%0.426SS..  trans-140109.3172.2-85.9147.6-19.600109.9P177 D194P177-Q192 PolarHBondContact O-NE2 2.94Å; P177-Q192 PolarHBondContact O-OE1 2.75Å; Q192-D194 PolarHBondContact O-N 3.04Å
193R58.9Low73.4Confident240 Ų24075.9 Ų75.991%0.90642%0.415SS*.THydrogen-bonded Turntrans-62.2-10.8-177.7-73.8-175-176.3-177.91114.6
194D73.2Confident74.1Confident125 Ų12572.6 Ų72.667%0.66840%0.399SS*.THydrogen-bonded Turntrans-106.53.8-169.5-53.6-38.2000114Q192Q192-D194 PolarHBondContact O-N 3.04Å
195C84.3Confident75.2Confident19 Ų1973.6 Ų73.613%0.12840%0.395CS..SBendtrans-108.4136179.9-61.10000111.6C178 T197C178-C195 WeakPolarHBondContact CA-SG 3.15Å; C178-C195 HydrophobicContact CB-CB 3.82Å; C178-C195 WeakPolarHBondContact CB-SG 3.43Å; C178-C195 WeakPolarHBondContact SG-CB 3.31Å; C178-C195 CovalentContact SG-SG 2.05Å; C178-C195 PolarHBondContact SG-SG 2.87Å; C195-T197 HydrophobicContact CB-CG2 4.48Å; C195-T197 PolarHBondContact O-N 3Å
196Y84.8Confident76.9Confident92 Ų9268.4 Ų68.436%0.36137%0.367SS..  trans-78.1101.1172.7-73-103.4000109.7V108 D164 M165 G166 C167V108-Y196 HydrophobicContact CG1-CD1 4.23Å; V108-Y196 HydrophobicContact CG1-CE1 3.86Å; V108-Y196 HydrophobicContact CG2-CD1 4.28Å; V108-Y196 HydrophobicContact CG2-CE1 3.87Å; D164-Y196 VanDerWaalsContact O-CD2 3.26Å; D164-Y196 WeakPolarHBondContact O-CD2 3.37Å; M165-Y196 HydrophobicContact CB-CD2 4.39Å; M165-Y196 HydrophobicContact CB-CE1 4.46Å; M165-Y196 HydrophobicContact CB-CE2 4.14Å; M165-Y196 HydrophobicContact CG-CE2 4.04Å; G166-Y196 CarbonylContact C-O 3.46Å; C167-Y196 WeakPolarHBondContact CA-O 3.48Å; C167-Y196 VanDerWaalsContact CB-O 3.27Å; C167-Y196 WeakPolarHBondContact CB-O 3.3Å; C167-Y196 PolarHBondContact N-O 3.13Å
197T82.9Confident78.8Confident18 Ų1870.5 Ų70.511%0.1137%0.365CS..  trans-100.9-18.5-18055.70000114.4P179 P182 S188 C195P179-T197 HydrophobicContact CG-CG2 3.9Å; P182-T197 VanDerWaalsContact CD-O 3.22Å; P182-T197 WeakPolarHBondContact CD-O 3.47Å; P182-T197 WeakPolarHBondContact CG-O 3.34Å; S188-T197 PolarHBondContact OG-OG1 3.09Å; S188-T197 VanDerWaalsContact OG-OG1 3.13Å; C195-T197 HydrophobicContact CB-CG2 4.48Å; C195-T197 PolarHBondContact O-N 3Å
198D84.7Confident81.1Confident126 Ų12669.8 Ų69.867%0.67435%0.354SS*.SBendtrans-89.4-17-164.6-56.8-19.8000113.2A519D198-A519 WeakPolarHBondContact O-CA 3.45Å
199V91.5Very high83.2Confident13 Ų1369.2 Ų69.28%0.07935%0.347CS..SBendtrans-136.4134.7176.2680000110.1G166 C167 T510 C520G166-V199 CarbonylContact C-O 3.5Å; G166-V199 WeakPolarHBondContact CA-O 3.18Å; C167-V199 PolarHBondContact N-O 3.35Å; V199-T510 HydrophobicContact CB-CG2 4.07Å; V199-T510 HydrophobicContact CG1-CG2 4.01Å; V199-T510 HydrophobicContact CG2-CG2 3.66Å; V199-C520 HydrophobicContact CG2-CB 4.17Å
200A96Very high85.5Confident0 Ų068.7 Ų68.70%034%0.34CS..BIsolated β-bridgetrans-74.1143.9172.400000111.1C167 P202 Q212 P213 A519C167-A200 WeakPolarHBondContact O-CA 3.4Å; A200-P202 WeakPolarHBondContact O-CD 3.42Å; A200-Q212 HydrophobicContact CB-CG 3.67Å; A200-Q212 PolarHBondContact O-NE2 3.33Å; A200-P213 HydrophobicContact CB-CB 3.75Å; A200-P213 HydrophobicContact CB-CG 4.39Å; A200-A519 HydrophobicContact CB-CB 4.26Å; A200-A519 WeakPolarHBondContact CB-O 3.31Å; A200-A519 PolarHBondContact N-O 2.82Å
201L97.3Very high87.7Confident0 Ų063.9 Ų63.90%031%0.313CS..PPolyproline II helixtrans-62.3127174.3-175.668.7000110.2I159 Y161 H163 C167 T168 P213 V214 L216I159-L201 HydrophobicContact CB-CD1 4.49Å; I159-L201 HydrophobicContact CG2-CD2 4.16Å; I159-L201 HydrophobicContact CG2-CG 4.29Å; Y161-L201 HydrophobicContact CD2-CD1 3.95Å; Y161-L201 HydrophobicContact CE2-CD1 3.62Å; H163-L201 HydrophobicContact CB-CD2 3.41Å; H163-L201 VanDerWaalsContact CB-CD2 3.41Å; C167-L201 PolarHBondContact O-N 2.88Å; T168-L201 HydrophobicContact CG2-CB 4.12Å; T168-L201 HydrophobicContact CG2-CD2 4.33Å; L201-P213 CarbonylContact O-C 3.56Å; L201-P213 WeakPolarHBondContact O-CA 3.45Å; L201-V214 HydrophobicContact CB-CG2 4.18Å; L201-V214 HydrophobicContact CD2-CB 4.04Å; L201-V214 HydrophobicContact CD2-CG2 3.93Å; L201-V214 HydrophobicContact CG-CB 4.38Å; L201-V214 HydrophobicContact CG-CG2 3.81Å; L201-V214 VanDerWaalsContact O-CG2 3.27Å; L201-V214 WeakPolarHBondContact O-CG2 3.47Å; L201-V214 PolarHBondContact O-N 3.44Å; L201-L216 HydrophobicContact CD2-CD2 4.16Å
202P97.9Very high90Very high0 Ų057.2 Ų57.20%028%0.278CS..PPolyproline II helixtrans-89.7148.3173.936.6-38.7000112.2P160 Y161 A200 Y204 I209 E211 Q212 V214 P511P160-P202 WeakPolarHBondContact CD-O 3.36Å; P160-P202 HydrophobicContact CG-CG 3.7Å; Y161-P202 WeakPolarHBondContact OH-CD 3.45Å; A200-P202 WeakPolarHBondContact O-CD 3.42Å; P202-Y204 HydrophobicContact CB-CD2 4.35Å; P202-Y204 HydrophobicContact CB-CE2 3.94Å; P202-Y204 HydrophobicContact CG-CD2 4.48Å; P202-Y204 HydrophobicContact CG-CE2 3.89Å; P202-I209 HydrophobicContact CB-CD1 4.25Å; P202-I209 HydrophobicContact CB-CG1 4.29Å; P202-I209 HydrophobicContact CB-CG2 3.98Å; P202-E211 CarbonylContact C-O 3.5Å; P202-E211 WeakPolarHBondContact CA-O 3.12Å; P202-Q212 HydrophobicContact CB-CB 4.46Å; P202-Q212 HydrophobicContact CB-CG 4.32Å; P202-V214 VanDerWaalsContact C-CG2 3.49Å; P202-P511 HydrophobicContact CB-CB 4.23Å; P202-P511 HydrophobicContact CG-CB 3.76Å; P202-P511 HydrophobicContact CG-CG 4.17Å
203L98.6Very high91.8Very high1 Ų154.3 Ų54.31%0.00527%0.266CS..EExtended strand (participates in β ladder)trans-113.3127.2165.2179.763.9000108.7F157 I159 I209 V210 E211 V214 L219 K222 Y223F157-L203 HydrophobicContact CE1-CD1 4.12Å; F157-L203 HydrophobicContact CE1-CD2 4.31Å; F157-L203 HydrophobicContact CE2-CD2 4.24Å; F157-L203 HydrophobicContact CE2-CG 4.37Å; F157-L203 HydrophobicContact CZ-CD1 4.18Å; F157-L203 HydrophobicContact CZ-CD2 3.7Å; F157-L203 HydrophobicContact CZ-CG 4.14Å; I159-L203 HydrophobicContact CG2-CD1 4.25Å; L203-I209 WeakPolarHBondContact O-CA 3.49Å; L203-V210 HydrophobicContact CB-CG2 4.44Å; L203-V210 HydrophobicContact CD2-CG2 4.35Å; L203-V210 HydrophobicContact CG-CG2 4.09Å; L203-V210 WeakPolarHBondContact O-CG2 3.36Å; L203-V210 PolarHBondContact O-N 3.38Å; L203-E211 HydrophobicContact CB-CB 4.12Å; L203-E211 HydrophobicContact CD2-CB 4.35Å; L203-E211 WeakPolarHBondContact CD2-OE2 3.29Å; L203-E211 PolarHBondContact N-O 3.16Å; L203-E211 PolarHBondContact O-N 3.43Å; L203-V214 HydrophobicContact CB-CG2 3.61Å; L203-L219 HydrophobicContact CD1-CD1 4.01Å; L203-L219 HydrophobicContact CD2-CD1 4.37Å; L203-K222 HydrophobicContact CD2-CD 4.29Å; L203-Y223 HydrophobicContact CD1-CE1 4.32Å
204Y98.7Very high93.5Very high24 Ų2443 Ų439%0.09422%0.223CC..EExtended strand (participates in β ladder)trans-99.5145.5179.9-78.7-101.2000111.8H147 Y156 F157 G158 P160 P202 N208 I209 P511H147-Y204 AromaticContact NE2-CD1 3.72Å; Y156-Y204 HydrophobicContact CE1-CG 4.19Å; F157-Y204 VanDerWaalsContact CA-O 3.29Å; F157-Y204 WeakPolarHBondContact CA-O 3.41Å; G158-Y204 PolarHBondContact N-O 3.22Å; G158-Y204 PolarHBondContact O-N 3.03Å; P160-Y204 HydrophobicContact CB-CE2 4.43Å; P160-Y204 HydrophobicContact CG-CD2 4.33Å; P160-Y204 HydrophobicContact CG-CE2 3.98Å; P202-Y204 HydrophobicContact CB-CD2 4.35Å; P202-Y204 HydrophobicContact CB-CE2 3.94Å; P202-Y204 HydrophobicContact CG-CD2 4.48Å; P202-Y204 HydrophobicContact CG-CE2 3.89Å; Y204-N208 CarbonylContact C-O 3.38Å; Y204-N208 VanDerWaalsContact CA-O 3.29Å; Y204-N208 WeakPolarHBondContact CA-O 3.47Å; Y204-I209 HydrophobicContact CD1-CG1 4.24Å; Y204-I209 HydrophobicContact CD2-CG1 4.43Å; Y204-I209 HydrophobicContact CE1-CG1 3.7Å; Y204-I209 HydrophobicContact CE2-CG1 3.91Å; Y204-P511 HydrophobicContact CE2-CB 4.38Å; Y204-P511 WeakPolarHBondContact OH-CB 3.36Å
205E98.6Very high94.6Very high57 Ų5740.1 Ų40.127%0.26621%0.208SC..EExtended strand (participates in β ladder)trans-121.1111.9153.2-174.6155.2-156.300108.5Y155 Y156 F157 L207 N208 V210 K226Y155-E205 HydrophobicContact CE2-CG 4.12Å; Y155-E205 WeakPolarHBondContact CE2-OE1 3.43Å; Y155-E205 PolarHBondContact OH-OE1 2.74Å; Y156-E205 CarbonylContact O-C 3.58Å; Y156-E205 WeakPolarHBondContact O-CA 3.43Å; F157-E205 HydrophobicContact CD2-CB 3.97Å; F157-E205 HydrophobicContact CD2-CG 4.21Å; E205-L207 PolarHBondContact O-N 2.97Å; E205-N208 PolarHBondContact N-O 3.25Å; E205-N208 PolarHBondContact O-N 2.92Å; E205-N208 VanDerWaalsContact O-N 3.12Å; E205-V210 HydrophobicContact CB-CG1 3.63Å; E205-V210 HydrophobicContact CB-CG2 4.3Å; E205-K226 IonicContact OE1-NZ 3.39Å; E205-K226 PolarHBondContact OE1-NZ 3.08Å; E205-K226 IonicContact OE2-NZ 2.77Å; E205-K226 PolarHBondContact OE2-NZ 2.9Å
206N98.5Very high95Very high50 Ų5039.4 Ų39.427%0.26720%0.203SC..THydrogen-bonded Turntrans48.5-121.4-163.1-60-49.8000110.7H147 N149 Y155 Y156 N208H147-N206 PolarHBondContact CE1-O 2.66Å; H147-N206 PolarHBondContact NE2-O 2.9Å; N149-N206 PolarHBondContact ND2-OD1 3.39Å; N149-N206 VanDerWaalsContact OD1-CA 3.23Å; N149-N206 WeakPolarHBondContact OD1-CA 3.21Å; Y155-N206 WeakPolarHBondContact CA-OD1 3.46Å; Y156-N206 PolarHBondContact N-OD1 3.12Å; Y156-N206 PolarHBondContact O-N 3.32Å; N206-N208 VanDerWaalsContact C-N 3.34Å
207L97.8Very high95.3Very high95 Ų9537.4 Ų37.450%0.49720%0.202SC..THydrogen-bonded Turntrans-84.8-6.5-176.5-56.2-178.9000113.8N149 F150 E205N149-L207 HydrophobicContact CB-CD2 4.11Å; F150-L207 HydrophobicContact CE2-CD2 3.85Å; F150-L207 HydrophobicContact CZ-CD1 4.15Å; F150-L207 HydrophobicContact CZ-CD2 3.93Å; E205-L207 PolarHBondContact O-N 2.97Å
208N97.9Very high95.8Very high113 Ų11338 Ų3860%0.60421%0.207SC*.EExtended strand (participates in β ladder)trans-102133.7-172.8-60.6-51.1000111Y204 E205 N206 V210Y204-N208 CarbonylContact C-O 3.38Å; Y204-N208 VanDerWaalsContact CA-O 3.29Å; Y204-N208 WeakPolarHBondContact CA-O 3.47Å; E205-N208 PolarHBondContact N-O 3.25Å; E205-N208 PolarHBondContact O-N 2.92Å; E205-N208 VanDerWaalsContact O-N 3.12Å; N206-N208 VanDerWaalsContact C-N 3.34Å; N208-V210 PolarHBondContact O-N 3.36Å
209I98.3Very high96.3Very high35 Ų3532.4 Ų32.418%0.17918%0.177CC..EExtended strand (participates in β ladder)trans-72.4116.5165.2-58.4173.1000107.3P202 L203 Y204 Q212 P511 C513P202-I209 HydrophobicContact CB-CD1 4.25Å; P202-I209 HydrophobicContact CB-CG1 4.29Å; P202-I209 HydrophobicContact CB-CG2 3.98Å; L203-I209 WeakPolarHBondContact O-CA 3.49Å; Y204-I209 HydrophobicContact CD1-CG1 4.24Å; Y204-I209 HydrophobicContact CD2-CG1 4.43Å; Y204-I209 HydrophobicContact CE1-CG1 3.7Å; Y204-I209 HydrophobicContact CE2-CG1 3.91Å; I209-Q212 HydrophobicContact CG2-CB 3.88Å; I209-P511 HydrophobicContact CD1-CB 4.04Å; I209-C513 HydrophobicContact CG2-CB 4.07Å
210V97.6Very high96.6Very high71 Ų7132 Ų3243%0.4318%0.175SC..EExtended strand (participates in β ladder)trans-99-18.8-179.4-65.50000112.8F157 L203 E205 N208F157-V210 HydrophobicContact CE2-CG2 4.4Å; L203-V210 HydrophobicContact CB-CG2 4.44Å; L203-V210 HydrophobicContact CD2-CG2 4.35Å; L203-V210 HydrophobicContact CG-CG2 4.09Å; L203-V210 WeakPolarHBondContact O-CG2 3.36Å; L203-V210 PolarHBondContact O-N 3.38Å; E205-V210 HydrophobicContact CB-CG1 3.63Å; E205-V210 HydrophobicContact CB-CG2 4.3Å; N208-V210 PolarHBondContact O-N 3.36Å
211E97.4Very high96.6Very high42 Ų4236.1 Ų36.120%0.19620%0.195CC..EExtended strand (participates in β ladder)trans-155.9130.6179.5179.7-177.9178.800109.8P202 L203 P213 N215 K222P202-E211 CarbonylContact C-O 3.5Å; P202-E211 WeakPolarHBondContact CA-O 3.12Å; L203-E211 HydrophobicContact CB-CB 4.12Å; L203-E211 HydrophobicContact CD2-CB 4.35Å; L203-E211 WeakPolarHBondContact CD2-OE2 3.29Å; L203-E211 PolarHBondContact N-O 3.16Å; L203-E211 PolarHBondContact O-N 3.43Å; E211-P213 WeakPolarHBondContact CG-O 3.25Å; E211-N215 WeakPolarHBondContact OE1-CB 3.29Å; E211-N215 PolarHBondContact OE1-N 3.41Å; E211-K222 VanDerWaalsContact CD-NZ 3.34Å; E211-K222 IonicContact OE1-NZ 3.57Å; E211-K222 PolarHBondContact OE1-NZ 2.92Å; E211-K222 IonicContact OE2-NZ 3.55Å; E211-K222 PolarHBondContact OE2-NZ 3.28Å
212Q97.1Very high96.6Very high6 Ų638.7 Ų38.73%0.02821%0.206CC..SBendtrans-158111.8175.1-175169.223.500107.7A200 P202 I209 P511 C513 C520 R521 C522A200-Q212 HydrophobicContact CB-CG 3.67Å; A200-Q212 PolarHBondContact O-NE2 3.33Å; P202-Q212 HydrophobicContact CB-CB 4.46Å; P202-Q212 HydrophobicContact CB-CG 4.32Å; I209-Q212 HydrophobicContact CG2-CB 3.88Å; Q212-P511 PolarHBondContact NE2-O 3.04Å; Q212-C513 HydrophobicContact CB-CB 4.16Å; Q212-C513 VanDerWaalsContact OE1-CB 3.24Å; Q212-C520 PolarHBondContact OE1-O 3.37Å; Q212-R521 CarbonylContact O-C 3.57Å; Q212-R521 VanDerWaalsContact O-CA 3.28Å; Q212-R521 WeakPolarHBondContact O-CA 3.43Å; Q212-C522 PolarHBondContact O-N 2.83Å
213P95.9Very high96.7Very high14 Ų1438.7 Ų38.79%0.09121%0.206CC..SBendcis-72.1148.41.527.4-33.5000114.2D169 A200 L201 E211D169-P213 WeakPolarHBondContact OD2-CG 3.27Å; A200-P213 HydrophobicContact CB-CB 3.75Å; A200-P213 HydrophobicContact CB-CG 4.39Å; L201-P213 CarbonylContact O-C 3.56Å; L201-P213 WeakPolarHBondContact O-CA 3.45Å; E211-P213 WeakPolarHBondContact CG-O 3.25Å
214V95.8Very high96.7Very high2 Ų238.7 Ų38.71%0.01221%0.206CC..  trans-65.1134.6169.2-173.50000111.8I159 T168 L201 P202 L203 L216 L219I159-V214 HydrophobicContact CG2-CG2 4.21Å; T168-V214 WeakPolarHBondContact CB-O 3.49Å; T168-V214 WeakPolarHBondContact CG2-O 3.49Å; L201-V214 HydrophobicContact CB-CG2 4.18Å; L201-V214 HydrophobicContact CD2-CB 4.04Å; L201-V214 HydrophobicContact CD2-CG2 3.93Å; L201-V214 HydrophobicContact CG-CB 4.38Å; L201-V214 HydrophobicContact CG-CG2 3.81Å; L201-V214 VanDerWaalsContact O-CG2 3.27Å; L201-V214 WeakPolarHBondContact O-CG2 3.47Å; L201-V214 PolarHBondContact O-N 3.44Å; P202-V214 VanDerWaalsContact C-CG2 3.49Å; L203-V214 HydrophobicContact CB-CG2 3.61Å; V214-L216 HydrophobicContact CG1-CD2 4.44Å; V214-L216 PolarHBondContact O-N 3.25Å; V214-L219 HydrophobicContact CG1-CD1 3.92Å; V214-L219 HydrophobicContact CG1-CD2 4.2Å; V214-L219 HydrophobicContact CG1-CG 4.46Å
215N94.3Very high96.7Very high65 Ų6541.6 Ų41.635%0.34822%0.22SC..  trans-8399.7165.5-177.7-22.3000111.1E211 S217 S218 L219E211-N215 WeakPolarHBondContact OE1-CB 3.29Å; E211-N215 PolarHBondContact OE1-N 3.41Å; N215-S217 VanDerWaalsContact C-N 3.29Å; N215-S217 PolarHBondContact O-N 3.23Å; N215-S217 PolarHBondContact OD1-N 2.74Å; N215-S217 VanDerWaalsContact OD1-N 3.12Å; N215-S218 PolarHBondContact O-N 3.16Å; N215-S218 VanDerWaalsContact O-N 3.13Å; N215-S218 PolarHBondContact O-OG 3Å; N215-L219 PolarHBondContact O-N 3.4Å
216L93.2Very high96.7Very high3 Ų340.7 Ų40.72%0.01622%0.216CC..Hα-helixtrans-59.4-34.9-177.1-60.7-179.2000113.3H163 T168 L201 V214 S218 L219 P253 P255H163-L216 HydrophobicContact CB-CD2 4.07Å; T168-L216 HydrophobicContact CG2-CD1 4.14Å; T168-L216 HydrophobicContact CG2-CD2 4.25Å; T168-L216 HydrophobicContact CG2-CG 3.99Å; L201-L216 HydrophobicContact CD2-CD2 4.16Å; V214-L216 HydrophobicContact CG1-CD2 4.44Å; V214-L216 PolarHBondContact O-N 3.25Å; L216-S218 PolarHBondContact O-N 3.48Å; L216-L219 HydrophobicContact CD2-CD2 4.26Å; L216-L219 WeakPolarHBondContact O-CB 3.07Å; L216-L219 PolarHBondContact O-N 3Å; L216-P253 HydrophobicContact CD1-CG 3.76Å; L216-P255 HydrophobicContact CB-CB 4.48Å; L216-P255 HydrophobicContact CB-CG 4.45Å
217S91.2Very high96.7Very high50 Ų5038.3 Ų38.335%0.3520%0.203SC..Hα-helixtrans-67.2-16.5-180-58.30000113.9N215 V256N215-S217 VanDerWaalsContact C-N 3.29Å; N215-S217 PolarHBondContact O-N 3.23Å; N215-S217 PolarHBondContact OD1-N 2.74Å; N215-S217 VanDerWaalsContact OD1-N 3.12Å; S217-V256 PolarHBondContact OG-O 3.06Å
218S93.8Very high96.8Very high31 Ų3135 Ų3522%0.21719%0.187CC..Hα-helixtrans-105.8-8.9176.8690000113.6N215 L216 A220 Q221 K222N215-S218 PolarHBondContact O-N 3.16Å; N215-S218 VanDerWaalsContact O-N 3.13Å; N215-S218 PolarHBondContact O-OG 3Å; L216-S218 PolarHBondContact O-N 3.48Å; S218-A220 PolarHBondContact O-N 2.8Å; S218-Q221 PolarHBondContact O-N 2.91Å; S218-K222 WeakPolarHBondContact O-CG 3.37Å; S218-K222 PolarHBondContact O-N 3.14Å; S218-K222 WeakPolarHBondContact OG-CE 3.27Å; S218-K222 PolarHBondContact OG-NZ 3.09Å
219L96Very high96.8Very high8 Ų834 Ų344%0.04218%0.178CC..Hα-helixtrans-66.8-41.1-167.1-173.360.6000112.4L203 V214 N215 L216 Q221 K222 Y223 A248L203-L219 HydrophobicContact CD1-CD1 4.01Å; L203-L219 HydrophobicContact CD2-CD1 4.37Å; V214-L219 HydrophobicContact CG1-CD1 3.92Å; V214-L219 HydrophobicContact CG1-CD2 4.2Å; V214-L219 HydrophobicContact CG1-CG 4.46Å; N215-L219 PolarHBondContact O-N 3.4Å; L216-L219 HydrophobicContact CD2-CD2 4.26Å; L216-L219 WeakPolarHBondContact O-CB 3.07Å; L216-L219 PolarHBondContact O-N 3Å; L219-Q221 VanDerWaalsContact C-N 3.33Å; L219-Q221 PolarHBondContact O-N 2.95Å; L219-K222 PolarHBondContact O-N 2.91Å; L219-Y223 HydrophobicContact CD1-CD1 4.17Å; L219-Y223 HydrophobicContact CD1-CE1 3.51Å; L219-Y223 HydrophobicContact CD1-CE2 4.19Å; L219-Y223 HydrophobicContact CD2-CE2 4.13Å; L219-Y223 HydrophobicContact CG-CD2 4.36Å; L219-Y223 HydrophobicContact CG-CE1 4.08Å; L219-Y223 HydrophobicContact CG-CE2 3.82Å; L219-Y223 PolarHBondContact O-N 2.83Å; L219-A248 HydrophobicContact CD2-CB 4.28Å
220A96Very high96.8Very high5 Ų532.9 Ų32.94%0.04117%0.172CC..Hα-helixtrans-57.4-47.4177.300000111.6S218 Y223 A224 E275 L279S218-A220 PolarHBondContact O-N 2.8Å; A220-Y223 PolarHBondContact O-N 2.77Å; A220-A224 PolarHBondContact O-N 2.96Å; A220-E275 HydrophobicContact CB-CG 3.67Å; A220-L279 HydrophobicContact CB-CD1 4.23Å; A220-L279 VanDerWaalsContact O-CD1 3.3Å; A220-L279 WeakPolarHBondContact O-CD1 3.43Å
221Q96.8Very high96.9Very high86 Ų8629.5 Ų29.540%0.40215%0.151SC..Hα-helixtrans-66.5-42.2-179.8-176.656.930.700111.4S218 L219 Y223 A224 E225S218-Q221 PolarHBondContact O-N 2.91Å; L219-Q221 VanDerWaalsContact C-N 3.33Å; L219-Q221 PolarHBondContact O-N 2.95Å; Q221-Y223 VanDerWaalsContact C-N 3.31Å; Q221-Y223 PolarHBondContact O-N 3.46Å; Q221-A224 PolarHBondContact O-N 3.23Å; Q221-E225 WeakPolarHBondContact CG-OE1 3.33Å; Q221-E225 PolarHBondContact NE2-OE1 2.81Å; Q221-E225 WeakPolarHBondContact O-CB 3.41Å; Q221-E225 WeakPolarHBondContact O-CG 3.35Å; Q221-E225 PolarHBondContact O-N 3.47Å
222K98.3Very high96.9Very high54 Ų5431.3 Ų31.324%0.23516%0.16CC..Hα-helixtrans-58.7-42.2173.7-72.4170.6177164.50111.6F157 L203 E211 S218 L219 E225 K226F157-K222 HydrophobicContact CE1-CB 3.89Å; F157-K222 HydrophobicContact CZ-CB 4.02Å; F157-K222 HydrophobicContact CZ-CD 4.5Å; L203-K222 HydrophobicContact CD2-CD 4.29Å; E211-K222 VanDerWaalsContact CD-NZ 3.34Å; E211-K222 IonicContact OE1-NZ 3.57Å; E211-K222 PolarHBondContact OE1-NZ 2.92Å; E211-K222 IonicContact OE2-NZ 3.55Å; E211-K222 PolarHBondContact OE2-NZ 3.28Å; S218-K222 WeakPolarHBondContact O-CG 3.37Å; S218-K222 PolarHBondContact O-N 3.14Å; S218-K222 WeakPolarHBondContact OG-CE 3.27Å; S218-K222 PolarHBondContact OG-NZ 3.09Å; L219-K222 PolarHBondContact O-N 2.91Å; K222-E225 PolarHBondContact O-N 2.88Å; K222-K226 WeakPolarHBondContact O-CB 3.33Å; K222-K226 VanDerWaalsContact O-CG 3.31Å; K222-K226 WeakPolarHBondContact O-CG 3.26Å; K222-K226 PolarHBondContact O-N 3.45Å
223Y98.8Very high96.9Very high1 Ų137.1 Ų37.10%0.00419%0.187CC..Hα-helixtrans-63.9-45.1175.1-71.2-10.8000112.5I135 G136 F157 L203 L219 A220 Q221 E225 K226 A227 A248I135-Y223 HydrophobicContact CG2-CD1 3.68Å; I135-Y223 HydrophobicContact CG2-CE1 4.46Å; I135-Y223 HydrophobicContact CG2-CG 3.82Å; G136-Y223 VanDerWaalsContact CA-CZ 3.49Å; F157-Y223 AromaticContact CD1-CD1 3.82Å; F157-Y223 HydrophobicContact CD1-CD1 3.82Å; F157-Y223 AromaticContact CD1-CE1 4Å; F157-Y223 HydrophobicContact CD1-CE1 4Å; F157-Y223 AromaticContact CE1-CD1 3.78Å; F157-Y223 HydrophobicContact CE1-CD1 3.78Å; F157-Y223 AromaticContact CE1-CE1 3.98Å; F157-Y223 HydrophobicContact CE1-CE1 3.98Å; L203-Y223 HydrophobicContact CD1-CE1 4.32Å; L219-Y223 HydrophobicContact CD1-CD1 4.17Å; L219-Y223 HydrophobicContact CD1-CE1 3.51Å; L219-Y223 HydrophobicContact CD1-CE2 4.19Å; L219-Y223 HydrophobicContact CD2-CE2 4.13Å; L219-Y223 HydrophobicContact CG-CD2 4.36Å; L219-Y223 HydrophobicContact CG-CE1 4.08Å; L219-Y223 HydrophobicContact CG-CE2 3.82Å; L219-Y223 PolarHBondContact O-N 2.83Å; A220-Y223 PolarHBondContact O-N 2.77Å; Q221-Y223 VanDerWaalsContact C-N 3.31Å; Q221-Y223 PolarHBondContact O-N 3.46Å; Y223-E225 PolarHBondContact O-N 2.96Å; Y223-K226 PolarHBondContact O-N 2.89Å; Y223-A227 WeakPolarHBondContact O-CB 2.97Å; Y223-A227 PolarHBondContact O-N 3.4Å; Y223-A248 HydrophobicContact CE2-CB 4.24Å
224A98.7Very high96.9Very high0 Ų036.6 Ų36.60%018%0.184CC..Hα-helixtrans-58.8-46.4175.300000111.5A220 Q221 A227 T228 L279 Q282A220-A224 PolarHBondContact O-N 2.96Å; Q221-A224 PolarHBondContact O-N 3.23Å; A224-A227 PolarHBondContact O-N 2.81Å; A224-T228 WeakPolarHBondContact O-CB 3.3Å; A224-T228 WeakPolarHBondContact O-CG2 3.39Å; A224-T228 PolarHBondContact O-N 2.8Å; A224-T228 PolarHBondContact O-OG1 2.81Å; A224-L279 HydrophobicContact CB-CG 4.17Å; A224-Q282 HydrophobicContact CB-CB 4.48Å
225E98.7Very high96.9Very high85 Ų8537.5 Ų37.540%0.39719%0.19SC..Hα-helixtrans-61.2-50.2178.4-74.5170.6-168.300112.1Q221 K222 Y223 A227 T228 Q229Q221-E225 WeakPolarHBondContact CG-OE1 3.33Å; Q221-E225 PolarHBondContact NE2-OE1 2.81Å; Q221-E225 WeakPolarHBondContact O-CB 3.41Å; Q221-E225 WeakPolarHBondContact O-CG 3.35Å; Q221-E225 PolarHBondContact O-N 3.47Å; K222-E225 PolarHBondContact O-N 2.88Å; Y223-E225 PolarHBondContact O-N 2.96Å; E225-A227 PolarHBondContact O-N 3.49Å; E225-T228 PolarHBondContact O-N 2.88Å; E225-T228 PolarHBondContact O-OG1 2.99Å; E225-Q229 WeakPolarHBondContact O-CB 3.35Å; E225-Q229 WeakPolarHBondContact O-CG 3.43Å; E225-Q229 PolarHBondContact O-N 2.93Å
226K98.8Very high96.9Very high39 Ų3939.4 Ų39.417%0.1721%0.205CC..Hα-helixtrans-67.3-38.4-179.3-65.9-61.7-159.5164.40112.3I135 Y155 F157 E205 K222 Y223 F230I135-K226 HydrophobicContact CD1-CB 3.8Å; Y155-K226 WeakPolarHBondContact OH-CD 3.46Å; F157-K226 HydrophobicContact CB-CB 4.41Å; F157-K226 HydrophobicContact CB-CG 4.33Å; F157-K226 HydrophobicContact CD1-CB 4.08Å; F157-K226 HydrophobicContact CD1-CG 3.67Å; F157-K226 HydrophobicContact CD2-CD 4.35Å; F157-K226 HydrophobicContact CD2-CG 4.01Å; F157-K226 HydrophobicContact CE1-CG 3.86Å; F157-K226 HydrophobicContact CE2-CG 4.18Å; F157-K226 HydrophobicContact CG-CB 4.25Å; F157-K226 HydrophobicContact CG-CD 4.46Å; F157-K226 HydrophobicContact CG-CG 3.74Å; F157-K226 HydrophobicContact CZ-CG 4.09Å; E205-K226 IonicContact OE1-NZ 3.39Å; E205-K226 PolarHBondContact OE1-NZ 3.08Å; E205-K226 IonicContact OE2-NZ 2.77Å; E205-K226 PolarHBondContact OE2-NZ 2.9Å; K222-K226 WeakPolarHBondContact O-CB 3.33Å; K222-K226 VanDerWaalsContact O-CG 3.31Å; K222-K226 WeakPolarHBondContact O-CG 3.26Å; K222-K226 PolarHBondContact O-N 3.45Å; Y223-K226 PolarHBondContact O-N 2.89Å; K226-F230 WeakPolarHBondContact O-CB 3.44Å; K226-F230 PolarHBondContact O-N 2.7Å
227A98.9Very high96.9Very high0 Ų041.9 Ų41.90%022%0.222CC..Hα-helixtrans-62.3-46.3174.200000111.7I135 Y223 A224 E225 F230 I231 L243 I283I135-A227 HydrophobicContact CG1-CB 4.29Å; Y223-A227 WeakPolarHBondContact O-CB 2.97Å; Y223-A227 PolarHBondContact O-N 3.4Å; A224-A227 PolarHBondContact O-N 2.81Å; E225-A227 PolarHBondContact O-N 3.49Å; A227-F230 PolarHBondContact O-N 3.17Å; A227-I231 WeakPolarHBondContact O-CD1 3.38Å; A227-I231 WeakPolarHBondContact O-CG1 3.48Å; A227-I231 PolarHBondContact O-N 2.86Å; A227-L243 HydrophobicContact CB-CD2 4.08Å; A227-I283 HydrophobicContact CB-CD1 3.78Å; A227-I283 HydrophobicContact CB-CG1 3.86Å
228T98.7Very high96.9Very high26 Ų2642.2 Ų42.216%0.1623%0.234CC..Hα-helixtrans-70-34.9-179.158.20000112.8A224 E225 Q232 K286A224-T228 WeakPolarHBondContact O-CB 3.3Å; A224-T228 WeakPolarHBondContact O-CG2 3.39Å; A224-T228 PolarHBondContact O-N 2.8Å; A224-T228 PolarHBondContact O-OG1 2.81Å; E225-T228 PolarHBondContact O-N 2.88Å; E225-T228 PolarHBondContact O-OG1 2.99Å; T228-Q232 WeakPolarHBondContact O-CB 3.26Å; T228-Q232 PolarHBondContact O-N 3.14Å; T228-Q232 VanDerWaalsContact O-N 3.08Å; T228-K286 HydrophobicContact CG2-CB 3.7Å; T228-K286 HydrophobicContact CG2-CG 4.01Å
229Q98.6Very high96.9Very high90 Ų9046.9 Ų46.942%0.42125%0.246SC..Hα-helixtrans-63.2-46.8170.6-74.5171.811.200111.4E225 I231 Q232 Q233E225-Q229 WeakPolarHBondContact O-CB 3.35Å; E225-Q229 WeakPolarHBondContact O-CG 3.43Å; E225-Q229 PolarHBondContact O-N 2.93Å; Q229-I231 PolarHBondContact O-N 3.39Å; Q229-Q232 PolarHBondContact O-N 2.87Å; Q229-Q233 WeakPolarHBondContact O-CB 3.44Å; Q229-Q233 VanDerWaalsContact O-CG 3.31Å; Q229-Q233 WeakPolarHBondContact O-CG 3.29Å; Q229-Q233 PolarHBondContact O-N 2.99Å
230F98.8Very high97Very high12 Ų1247.4 Ų47.45%0.05325%0.25CS..Hα-helixtrans-58.1-50176.6177.8-87.7000111.3I131 G133 Y155 K226 A227 Q232 Q233 A234 F241 L243I131-F230 HydrophobicContact CG2-CE2 3.86Å; I131-F230 HydrophobicContact CG2-CZ 3.86Å; G133-F230 VanDerWaalsContact CA-CE2 3.48Å; Y155-F230 HydrophobicContact CD1-CD2 4.07Å; Y155-F230 HydrophobicContact CG-CD2 4.48Å; K226-F230 WeakPolarHBondContact O-CB 3.44Å; K226-F230 PolarHBondContact O-N 2.7Å; A227-F230 PolarHBondContact O-N 3.17Å; F230-Q232 VanDerWaalsContact C-N 3.28Å; F230-Q232 PolarHBondContact O-N 3.45Å; F230-Q233 PolarHBondContact O-N 2.88Å; F230-A234 HydrophobicContact CD1-CB 4.43Å; F230-A234 HydrophobicContact CE1-CB 4.14Å; F230-A234 HydrophobicContact CZ-CB 4.36Å; F230-A234 WeakPolarHBondContact O-CB 3.5Å; F230-A234 PolarHBondContact O-N 3.49Å; F230-F241 HydrophobicContact CE1-CB 4.07Å; F230-F241 AromaticContact CE1-CD2 3.96Å; F230-F241 HydrophobicContact CE1-CD2 3.96Å; F230-F241 HydrophobicContact CE1-CG 4.21Å; F230-F241 HydrophobicContact CZ-CB 4.33Å; F230-L243 HydrophobicContact CD1-CB 4.01Å; F230-L243 HydrophobicContact CD1-CD1 3.71Å; F230-L243 HydrophobicContact CD1-CD2 4.16Å; F230-L243 HydrophobicContact CD1-CG 4.16Å; F230-L243 HydrophobicContact CE1-CB 3.87Å; F230-L243 HydrophobicContact CE1-CD1 4.09Å; F230-L243 HydrophobicContact CE1-CG 4.45Å; F230-L243 HydrophobicContact CG-CD1 4.11Å
231I98.6Very high97.2Very high0 Ų047.2 Ų47.20%025%0.248CC..Hα-helixtrans-57.5-44.3178.9-69159.7000110.7A227 Q229 S235 F241 L243 I283 K286 V287 T290A227-I231 WeakPolarHBondContact O-CD1 3.38Å; A227-I231 WeakPolarHBondContact O-CG1 3.48Å; A227-I231 PolarHBondContact O-N 2.86Å; Q229-I231 PolarHBondContact O-N 3.39Å; I231-S235 WeakPolarHBondContact O-CB 3.16Å; I231-S235 PolarHBondContact O-N 2.92Å; I231-S235 PolarHBondContact O-OG 2.81Å; I231-F241 HydrophobicContact CG1-CE2 4.32Å; I231-F241 HydrophobicContact CG1-CZ 4.37Å; I231-F241 HydrophobicContact CG2-CZ 4.14Å; I231-L243 HydrophobicContact CD1-CD2 3.84Å; I231-L243 HydrophobicContact CG1-CD2 3.76Å; I231-I283 HydrophobicContact CD1-CG2 3.98Å; I231-K286 HydrophobicContact CB-CG 4Å; I231-K286 HydrophobicContact CD1-CG 4.27Å; I231-K286 HydrophobicContact CG2-CG 3.86Å; I231-V287 HydrophobicContact CD1-CG2 3.84Å; I231-V287 HydrophobicContact CG1-CG2 4.49Å; I231-V287 HydrophobicContact CG2-CG2 4.34Å; I231-T290 WeakPolarHBondContact CG2-OG1 3.3Å
232Q97.8Very high97.3Very high81 Ų8143.1 Ų43.138%0.37923%0.23SC..Hα-helixtrans-62.5-49.1179.4-176.262.666.300111.9T228 Q229 F230 T236T228-Q232 WeakPolarHBondContact O-CB 3.26Å; T228-Q232 PolarHBondContact O-N 3.14Å; T228-Q232 VanDerWaalsContact O-N 3.08Å; Q229-Q232 PolarHBondContact O-N 2.87Å; F230-Q232 VanDerWaalsContact C-N 3.28Å; F230-Q232 PolarHBondContact O-N 3.45Å; Q232-T236 WeakPolarHBondContact O-CG2 3.46Å; Q232-T236 PolarHBondContact O-N 2.77Å; Q232-T236 PolarHBondContact O-OG1 3.5Å
233Q97.4Very high97.3Very high128 Ų12840.6 Ų40.660%0.59822%0.218SC*.Hα-helixtrans-69.1-42.2-178-69.7173-1.200112.2Q229 F230 S235 T236 S237Q229-Q233 WeakPolarHBondContact O-CB 3.44Å; Q229-Q233 VanDerWaalsContact O-CG 3.31Å; Q229-Q233 WeakPolarHBondContact O-CG 3.29Å; Q229-Q233 PolarHBondContact O-N 2.99Å; F230-Q233 PolarHBondContact O-N 2.88Å; Q233-S235 VanDerWaalsContact C-N 3.33Å; Q233-S235 PolarHBondContact O-N 2.78Å; Q233-T236 PolarHBondContact O-N 3.42Å; Q233-T236 PolarHBondContact O-OG1 3.24Å; Q233-S237 PolarHBondContact O-N 3.22Å
234A96.7Very high97.3Very high3 Ų340.6 Ų40.63%0.02522%0.219CC..Hα-helixtrans-65.7-40.1178.300000110.9I131 F230 T236 S237 F241I131-A234 HydrophobicContact CD1-CB 4.37Å; F230-A234 HydrophobicContact CD1-CB 4.43Å; F230-A234 HydrophobicContact CE1-CB 4.14Å; F230-A234 HydrophobicContact CZ-CB 4.36Å; F230-A234 WeakPolarHBondContact O-CB 3.5Å; F230-A234 PolarHBondContact O-N 3.49Å; A234-T236 VanDerWaalsContact C-N 3.34Å; A234-T236 PolarHBondContact O-N 3.5Å; A234-S237 WeakPolarHBondContact O-CB 3.39Å; A234-S237 PolarHBondContact O-N 3.48Å; A234-S237 PolarHBondContact O-OG 2.89Å; A234-F241 HydrophobicContact CB-CB 3.7Å; A234-F241 HydrophobicContact CB-CD1 3.73Å; A234-F241 HydrophobicContact CB-CG 3.84Å
235S94.8Very high97.3Very high20 Ų2040.6 Ų40.614%0.1422%0.219CC..Hα-helixtrans-63.6-36177.4-63.30000113.2I231 Q233 S237I231-S235 WeakPolarHBondContact O-CB 3.16Å; I231-S235 PolarHBondContact O-N 2.92Å; I231-S235 PolarHBondContact O-OG 2.81Å; Q233-S235 VanDerWaalsContact C-N 3.33Å; Q233-S235 PolarHBondContact O-N 2.78Å; S235-S237 VanDerWaalsContact C-N 3.32Å
236T94.5Very high97.3Very high106 Ų10636.6 Ų36.665%0.6520%0.2SC*.Hα-helixtrans-76.4-18.1177.856.50000113.4Q232 Q233 A234 G238Q232-T236 WeakPolarHBondContact O-CG2 3.46Å; Q232-T236 PolarHBondContact O-N 2.77Å; Q232-T236 PolarHBondContact O-OG1 3.5Å; Q233-T236 PolarHBondContact O-N 3.42Å; Q233-T236 PolarHBondContact O-OG1 3.24Å; A234-T236 VanDerWaalsContact C-N 3.34Å; A234-T236 PolarHBondContact O-N 3.5Å; T236-G238 PolarHBondContact O-N 2.66Å
237S93.9Very high97.3Very high55 Ų5534.7 Ų34.739%0.38519%0.192SC..THydrogen-bonded Turntrans-70.1-17.5179800000114.5I131 Q233 A234 S235 R239I131-S237 WeakPolarHBondContact CD1-OG 3.43Å; Q233-S237 PolarHBondContact O-N 3.22Å; A234-S237 WeakPolarHBondContact O-CB 3.39Å; A234-S237 PolarHBondContact O-N 3.48Å; A234-S237 PolarHBondContact O-OG 2.89Å; S235-S237 VanDerWaalsContact C-N 3.32Å; S237-R239 PolarHBondContact O-N 3.3Å; S237-R239 PolarHBondContact OG-N 3.1Å; S237-R239 VanDerWaalsContact OG-N 3.12Å
238G89.6Confident97.1Very high57 Ų5735 Ų3559%0.58819%0.194SC*.SBendtrans75.9-5.6-172.700000115.2T236T236-G238 PolarHBondContact O-N 2.66Å
239R95.1Very high97Very high128 Ų12834.1 Ų34.148%0.48319%0.188SC..SBendtrans-88.5151.6173.6-65-168-71167.2-3.9111.3I131 S237I131-R239 HydrophobicContact CD1-CB 4.12Å; I131-R239 HydrophobicContact CG1-CB 4.08Å; I131-R239 VanDerWaalsContact CG1-CZ 3.4Å; I131-R239 VanDerWaalsContact CG1-NH2 3.34Å; S237-R239 PolarHBondContact O-N 3.3Å; S237-R239 PolarHBondContact OG-N 3.1Å; S237-R239 VanDerWaalsContact OG-N 3.12Å
240P98.2Very high96.9Very high20 Ų2030 Ų3013%0.1317%0.169CC..  trans-69.6157.7169.634.4-37000110.2K35 N37 Y130 I131K35-P240 HydrophobicContact CB-CB 4.1Å; K35-P240 HydrophobicContact CB-CG 4.1Å; K35-P240 HydrophobicContact CD-CG 4.48Å; N37-P240 WeakPolarHBondContact OD1-CA 3.48Å; Y130-P240 VanDerWaalsContact CA-O 3.3Å; Y130-P240 WeakPolarHBondContact CA-O 3.43Å; Y130-P240 HydrophobicContact CD1-CB 3.86Å; Y130-P240 HydrophobicContact CD1-CG 4.03Å; Y130-P240 HydrophobicContact CD2-CG 3.89Å; Y130-P240 HydrophobicContact CE1-CB 3.58Å; Y130-P240 HydrophobicContact CE1-CG 4Å; Y130-P240 HydrophobicContact CE2-CB 4.29Å; Y130-P240 HydrophobicContact CE2-CG 3.86Å; Y130-P240 HydrophobicContact CG-CB 4.3Å; Y130-P240 HydrophobicContact CG-CG 3.95Å; I131-P240 PolarHBondContact N-O 3.01Å
241F98.8Very high96.8Very high0 Ų029.7 Ų29.70%017%0.167CC..EExtended strand (participates in β ladder)trans-132.4151.3-179.167.4-101.1000114.1N37 F38 V39 I131 F230 I231 A234 L243 T295N37-F241 CarbonylContact C-O 3.52Å; N37-F241 WeakPolarHBondContact CA-O 3.4Å; N37-F241 HydrophobicContact CB-CD1 3.9Å; N37-F241 HydrophobicContact CB-CD2 4.1Å; N37-F241 HydrophobicContact CB-CE1 3.65Å; N37-F241 HydrophobicContact CB-CE2 3.85Å; N37-F241 HydrophobicContact CB-CG 4.12Å; N37-F241 HydrophobicContact CB-CZ 3.61Å; N37-F241 WeakPolarHBondContact ND2-CE1 3.36Å; N37-F241 WeakPolarHBondContact OD1-CD1 3.23Å; N37-F241 PolarHBondContact OD1-N 3.48Å; F38-F241 PolarHBondContact N-O 2.87Å; V39-F241 HydrophobicContact CG2-CE2 3.8Å; I131-F241 HydrophobicContact CB-CB 4.32Å; I131-F241 CarbonylContact O-C 3.53Å; I131-F241 WeakPolarHBondContact O-CA 3.2Å; I131-F241 WeakPolarHBondContact O-CB 3.41Å; F230-F241 HydrophobicContact CE1-CB 4.07Å; F230-F241 AromaticContact CE1-CD2 3.96Å; F230-F241 HydrophobicContact CE1-CD2 3.96Å; F230-F241 HydrophobicContact CE1-CG 4.21Å; F230-F241 HydrophobicContact CZ-CB 4.33Å; I231-F241 HydrophobicContact CG1-CE2 4.32Å; I231-F241 HydrophobicContact CG1-CZ 4.37Å; I231-F241 HydrophobicContact CG2-CZ 4.14Å; A234-F241 HydrophobicContact CB-CB 3.7Å; A234-F241 HydrophobicContact CB-CD1 3.73Å; A234-F241 HydrophobicContact CB-CG 3.84Å; F241-L243 HydrophobicContact CD2-CB 4.39Å; F241-T295 HydrophobicContact CZ-CG2 4.31Å
242L98.9Very high96.6Very high1 Ų129.8 Ų29.81%0.00517%0.168CC..EExtended strand (participates in β ladder)trans-109.7125.5163.316868.2000107.3F38 I40 A122 L125 I131 T132 G133 F153F38-L242 HydrophobicContact CB-CD1 3.92Å; F38-L242 CarbonylContact O-C 3.57Å; F38-L242 WeakPolarHBondContact O-CA 3.01Å; I40-L242 HydrophobicContact CD1-CD1 3.85Å; I40-L242 HydrophobicContact CG1-CD1 4.36Å; A122-L242 HydrophobicContact CB-CD2 4.13Å; L125-L242 HydrophobicContact CD1-CB 3.77Å; L125-L242 HydrophobicContact CD1-CD1 4.15Å; L125-L242 HydrophobicContact CD1-CD2 3.89Å; L125-L242 HydrophobicContact CD1-CG 4.11Å; I131-L242 PolarHBondContact O-N 3.04Å; T132-L242 CarbonylContact C-O 3.54Å; T132-L242 WeakPolarHBondContact CA-O 3.4Å; T132-L242 HydrophobicContact CG2-CB 4.27Å; T132-L242 HydrophobicContact CG2-CD2 4.4Å; G133-L242 PolarHBondContact N-O 2.76Å; F153-L242 HydrophobicContact CE1-CD2 4.2Å
243L98.9Very high96.4Very high0 Ų026.4 Ų26.40%015%0.153CC..EExtended strand (participates in β ladder)trans-117.3115.3165.5-179.660.5000109.1F38 V39 I40 G133 I135 A227 F230 I231 F241 V245F38-L243 PolarHBondContact O-N 3.13Å; V39-L243 CarbonylContact C-O 3.56Å; V39-L243 WeakPolarHBondContact CA-O 3.39Å; V39-L243 HydrophobicContact CG1-CD2 4.47Å; V39-L243 HydrophobicContact CG2-CB 4.26Å; I40-L243 PolarHBondContact N-O 3.47Å; G133-L243 WeakPolarHBondContact O-CA 3.39Å; I135-L243 HydrophobicContact CG1-CD1 3.81Å; A227-L243 HydrophobicContact CB-CD2 4.08Å; F230-L243 HydrophobicContact CD1-CB 4.01Å; F230-L243 HydrophobicContact CD1-CD1 3.71Å; F230-L243 HydrophobicContact CD1-CD2 4.16Å; F230-L243 HydrophobicContact CD1-CG 4.16Å; F230-L243 HydrophobicContact CE1-CB 3.87Å; F230-L243 HydrophobicContact CE1-CD1 4.09Å; F230-L243 HydrophobicContact CE1-CG 4.45Å; F230-L243 HydrophobicContact CG-CD1 4.11Å; I231-L243 HydrophobicContact CD1-CD2 3.84Å; I231-L243 HydrophobicContact CG1-CD2 3.76Å; F241-L243 HydrophobicContact CD2-CB 4.39Å; L243-V245 HydrophobicContact CD1-CG2 4.27Å; L243-V245 HydrophobicContact CD2-CG2 3.84Å; L243-V245 HydrophobicContact CG-CG2 3.63Å
244Y98.9Very high96.2Very high2 Ų220.4 Ų20.41%0.00813%0.125CC..EExtended strand (participates in β ladder)trans-100.2111.1172.2176.1-131.9000109.6I40 L42 L91 L92 G133 M134 I135 F153 A246I40-Y244 HydrophobicContact CB-CD2 4.23Å; I40-Y244 HydrophobicContact CG2-CD2 4.16Å; I40-Y244 HydrophobicContact CG2-CE2 4.47Å; I40-Y244 CarbonylContact O-C 3.53Å; I40-Y244 WeakPolarHBondContact O-CA 3.1Å; L42-Y244 HydrophobicContact CB-CE2 3.99Å; L42-Y244 HydrophobicContact CD2-CE2 4.24Å; L42-Y244 WeakPolarHBondContact CD2-OH 3.45Å; L91-Y244 HydrophobicContact CD1-CE2 4.24Å; L91-Y244 HydrophobicContact CD2-CE2 4.16Å; L92-Y244 HydrophobicContact CD1-CE1 4.29Å; L92-Y244 HydrophobicContact CD2-CD1 4.35Å; L92-Y244 HydrophobicContact CD2-CE1 4.28Å; G133-Y244 PolarHBondContact O-N 3Å; M134-Y244 CarbonylContact C-O 3.56Å; M134-Y244 VanDerWaalsContact CA-O 3.29Å; M134-Y244 WeakPolarHBondContact CA-O 3.34Å; M134-Y244 HydrophobicContact CE-CD1 4.1Å; M134-Y244 HydrophobicContact CE-CE1 3.87Å; M134-Y244 HydrophobicContact CG-CD1 3.92Å; M134-Y244 HydrophobicContact SD-CD1 3.85Å; M134-Y244 HydrophobicContact SD-CE1 4.1Å; I135-Y244 PolarHBondContact N-O 3.08Å; F153-Y244 HydrophobicContact CE1-CD1 4.39Å; F153-Y244 AromaticContact CZ-CD1 3.8Å; F153-Y244 HydrophobicContact CZ-CD1 3.8Å; F153-Y244 HydrophobicContact CZ-CG 4.36Å; Y244-A246 HydrophobicContact CD1-CB 4.44Å; Y244-A246 HydrophobicContact CE1-CB 3.84Å; Y244-A246 HydrophobicContact CE2-CB 4.23Å
245V98.9Very high95.6Very high0 Ų020.9 Ų20.90%013%0.128CC..EExtended strand (participates in β ladder)trans-106.695.3-177.7-169.10000108.5I40 I41 L42 I135 L243 L247 I283I40-V245 PolarHBondContact O-N 3.18Å; I41-V245 CarbonylContact C-O 3.17Å; I41-V245 WeakPolarHBondContact CA-O 3.37Å; I41-V245 HydrophobicContact CG1-CB 4.21Å; I41-V245 HydrophobicContact CG1-CG2 4.42Å; I41-V245 HydrophobicContact CG2-CB 4.44Å; L42-V245 PolarHBondContact N-O 3.29Å; I135-V245 HydrophobicContact CB-CG1 4.46Å; I135-V245 CarbonylContact O-C 3.54Å; I135-V245 WeakPolarHBondContact O-CA 3.48Å; L243-V245 HydrophobicContact CD1-CG2 4.27Å; L243-V245 HydrophobicContact CD2-CG2 3.84Å; L243-V245 HydrophobicContact CG-CG2 3.63Å; V245-L247 HydrophobicContact CG1-CD2 3.59Å; V245-L247 HydrophobicContact CG1-CG 4.41Å; V245-I283 HydrophobicContact CG1-CD1 3.89Å; V245-I283 HydrophobicContact CG2-CD1 4.13Å
246A98.6Very high94.5Very high0 Ų023.3 Ų23.30%014%0.141CC..EExtended strand (participates in β ladder)trans-96.891.2-178.200000109.3L42 M134 I135 G136 K137 Y244L42-A246 CarbonylContact O-C 3.5Å; M134-A246 HydrophobicContact CE-CB 3.94Å; I135-A246 PolarHBondContact O-N 2.85Å; G136-A246 CarbonylContact C-O 3.55Å; G136-A246 WeakPolarHBondContact CA-O 3.09Å; K137-A246 PolarHBondContact N-O 2.85Å; K137-A246 WeakPolarHBondContact O-CB 3.43Å; Y244-A246 HydrophobicContact CD1-CB 4.44Å; Y244-A246 HydrophobicContact CE1-CB 3.84Å; Y244-A246 HydrophobicContact CE2-CB 4.23Å
247L98Very high93Very high0 Ų019.9 Ų19.90%012%0.12CC..  trans-64.4152.5-171.7-55.3177.1000111.7I41 L42 V245 H249 M276 L279 V280I41-L247 HydrophobicContact CG2-CD1 3.91Å; I41-L247 HydrophobicContact CG2-CG 4.24Å; L42-L247 PolarHBondContact O-N 3.37Å; V245-L247 HydrophobicContact CG1-CD2 3.59Å; V245-L247 HydrophobicContact CG1-CG 4.41Å; L247-H249 HydrophobicContact CB-CB 4.37Å; L247-M276 HydrophobicContact CD1-CG 3.61Å; L247-M276 HydrophobicContact CD1-SD 4.13Å; L247-L279 HydrophobicContact CD2-CD1 3.92Å; L247-L279 HydrophobicContact CD2-CD2 3.56Å; L247-L279 HydrophobicContact CD2-CG 4.46Å; L247-V280 HydrophobicContact CD1-CG2 4.15Å
248A95.8Very high91.1Very high5 Ų526.6 Ų26.64%0.04115%0.146CC..  trans-81.4-30.316500000110.6I159 H163 L219 Y223 H251I159-A248 HydrophobicContact CD1-CB 4.11Å; H163-A248 PolarHBondContact CE1-O 2.84Å; L219-A248 HydrophobicContact CD2-CB 4.28Å; Y223-A248 HydrophobicContact CE2-CB 4.24Å; A248-H251 WeakPolarHBondContact O-CB 3.44Å; A248-H251 PolarHBondContact O-N 3.17Å; A248-H251 VanDerWaalsContact O-N 3.07Å
249H96.3Very high89.5Confident9 Ų927.9 Ų27.94%0.04214%0.139CC..THydrogen-bonded Turntrans-62.2139.2166.9-65.678.9000110.6D44 L247 G272 E275 M276D44-H249 WeakPolarHBondContact CB-O 3.45Å; D44-H249 PolarHBondContact N-O 2.93Å; D44-H249 CarbonylContact O-C 3.46Å; L247-H249 HydrophobicContact CB-CB 4.37Å; H249-G272 PolarHBondContact CD2-O 3.25Å; H249-E275 IonicContact CD2-OE2 3.95Å; H249-E275 IonicContact CE1-OE2 3.64Å; H249-E275 PolarHBondContact CE1-OE2 3.21Å; H249-E275 IonicContact NE2-OE2 3.72Å; H249-E275 PolarHBondContact NE2-OE2 3.4Å; H249-M276 HydrophobicContact CB-CB 3.74Å; H249-M276 HydrophobicContact CB-CG 3.6Å; H249-M276 HydrophobicContact CB-SD 3.92Å
250M96.3Very high87.3Confident3 Ų325.9 Ų25.92%0.01514%0.142CC..THydrogen-bonded Turncis-103.621.64.1-71.7-58.5-58.900113.5D44 L254 Y269 G272 L273 M276D44-M250 CarbonylContact O-C 3.47Å; D44-M250 WeakPolarHBondContact O-CA 3.41Å; D44-M250 PolarHBondContact O-N 2.81Å; M250-L254 HydrophobicContact CE-CD2 4.05Å; M250-Y269 HydrophobicContact CB-CE2 3.79Å; M250-Y269 HydrophobicContact CE-CD1 4.33Å; M250-Y269 HydrophobicContact CE-CD2 3.68Å; M250-Y269 HydrophobicContact CE-CE1 4.16Å; M250-Y269 HydrophobicContact CE-CE2 3.52Å; M250-Y269 HydrophobicContact CE-CG 4.11Å; M250-Y269 VanDerWaalsContact CE-O 3.31Å; M250-Y269 WeakPolarHBondContact CE-O 3.34Å; M250-Y269 HydrophobicContact CG-CE2 4.28Å; M250-G272 VanDerWaalsContact CE-C 3.49Å; M250-L273 HydrophobicContact CE-CB 4.06Å; M250-L273 VanDerWaalsContact CE-N 3.3Å; M250-L273 HydrophobicContact CG-CD1 4.25Å; M250-L273 HydrophobicContact SD-CB 4.27Å; M250-L273 HydrophobicContact SD-CD1 4.31Å; M250-M276 HydrophobicContact CG-SD 3.8Å; M250-M276 HydrophobicContact SD-CB 4.07Å; M250-M276 HydrophobicContact SD-SD 4.16Å
251H97.2Very high84.9Confident5 Ų530.5 Ų30.52%0.02318%0.182CC..SBendtrans-64.7146.1179.7-162.5-73.8000110.7D44 D45 H163 D164 A248 W306 K333D44-H251 HydrophobicContact CB-CB 3.98Å; D44-H251 PolarHBondContact O-N 2.96Å; D44-H251 IonicContact OD1-CD2 3.92Å; D44-H251 VanDerWaalsContact OD2-CB 3.23Å; D44-H251 WeakPolarHBondContact OD2-CB 3.44Å; D44-H251 IonicContact OD2-CD2 2.73Å; D44-H251 IonicContact OD2-CG 2.72Å; D45-H251 VanDerWaalsContact CG-CD2 3.44Å; D45-H251 IonicContact OD1-CD2 3.79Å; D45-H251 IonicContact OD2-CD2 3.23Å; D45-H251 PolarHBondContact OD2-CD2 3.29Å; D45-H251 IonicContact OD2-CG 3.79Å; D45-H251 IonicContact OD2-NE2 3.54Å; H163-H251 PolarHBondContact CE1-O 2.93Å; H163-H251 PolarHBondContact NE2-O 2.81Å; D164-H251 VanDerWaalsContact CG-CE1 3.5Å; D164-H251 IonicContact OD1-CE1 3.17Å; D164-H251 PolarHBondContact OD1-CE1 3.27Å; D164-H251 VanDerWaalsContact OD1-CE1 3.23Å; D164-H251 IonicContact OD1-ND1 3.07Å; D164-H251 IonicContact OD2-CE1 3.54Å; A248-H251 WeakPolarHBondContact O-CB 3.44Å; A248-H251 PolarHBondContact O-N 3.17Å; A248-H251 VanDerWaalsContact O-N 3.07Å; H251-W306 AromaticContact CE1-CE3 3.9Å; H251-W306 AromaticContact CE1-CZ3 3.43Å; H251-W306 VanDerWaalsContact CE1-CZ3 3.43Å; H251-W306 WeakPolarHBondContact CE1-CZ3 3.3Å; H251-W306 AromaticContact NE2-CE3 3.91Å; H251-W306 AromaticContact NE2-CZ3 3.74Å; H251-K333 PolarHBondContact CD2-NZ 3.4Å; H251-K333 PolarHBondContact NE2-NZ 3.29Å
252V93.5Very high82.3Confident3 Ų333.1 Ų33.12%0.01820%0.204CC..SBendtrans-76.3156174-66.20000110.7H163 N174 L254 W306 K309 L312H163-V252 PolarHBondContact NE2-O 3.09Å; N174-V252 WeakPolarHBondContact OD1-CG2 3.43Å; V252-L254 HydrophobicContact CG1-CG 4.43Å; V252-W306 HydrophobicContact CG2-CE3 3.92Å; V252-W306 HydrophobicContact CG2-CZ3 3.89Å; V252-K309 HydrophobicContact CG1-CB 4.02Å; V252-K309 HydrophobicContact CG1-CG 4.09Å; V252-K309 HydrophobicContact CG2-CB 4.5Å; V252-K309 HydrophobicContact CG2-CD 3.73Å; V252-K309 HydrophobicContact CG2-CG 3.66Å; V252-L312 HydrophobicContact CG1-CB 3.86Å
253P94.4Very high79.8Confident9 Ų938.3 Ų38.36%0.05824%0.238CC..SBendcis-67.2142.2-5.126-34.3000113.5H163 P171 Y173 N174 L216H163-P253 VanDerWaalsContact CD2-CD 3.44Å; H163-P253 WeakPolarHBondContact CD2-CD 3.47Å; H163-P253 PolarHBondContact CD2-O 3.12Å; H163-P253 PolarHBondContact NE2-O 2.88Å; P171-P253 WeakPolarHBondContact O-CB 3.39Å; Y173-P253 CarbonylContact O-C 3.52Å; Y173-P253 WeakPolarHBondContact O-CA 3.33Å; N174-P253 HydrophobicContact CB-CB 4.21Å; L216-P253 HydrophobicContact CD1-CG 3.76Å
254L92.3Very high77.3Confident3 Ų350.4 Ų50.42%0.01628%0.283CS..BIsolated β-bridgetrans-78.4135.3172.8-59.5-178.8000109.9G172 Y173 M250 V252 L268 Y269 L312G172-L254 CarbonylContact C-O 3.57Å; G172-L254 WeakPolarHBondContact CA-O 3.28Å; Y173-L254 PolarHBondContact N-O 3.17Å; Y173-L254 PolarHBondContact O-N 3.34Å; M250-L254 HydrophobicContact CE-CD2 4.05Å; V252-L254 HydrophobicContact CG1-CG 4.43Å; L254-L268 HydrophobicContact CD1-CB 4.46Å; L254-Y269 HydrophobicContact CD1-CD2 4.33Å; L254-L312 HydrophobicContact CD1-CB 4.22Å; L254-L312 HydrophobicContact CD1-CD2 4.06Å
255P85.3Confident75.2Confident13 Ų1352.4 Ų52.48%0.08431%0.305CS..PPolyproline II helixtrans-58.1153.3-179.9-23.832.9000113.7L216 T257L216-P255 HydrophobicContact CB-CB 4.48Å; L216-P255 HydrophobicContact CB-CG 4.45Å; P255-T257 PolarHBondContact O-N 3.08Å
256V71.3Confident73.3Confident70 Ų7061.6 Ų61.642%0.42434%0.339SS..  trans-7987.2174.1-1740000109.2Y173 S217Y173-V256 HydrophobicContact CE2-CB 4.39Å; Y173-V256 HydrophobicContact CE2-CG1 4.34Å; Y173-V256 HydrophobicContact CE2-CG2 4.19Å; S217-V256 PolarHBondContact OG-O 3.06Å
257T62.8Low72.1Confident34 Ų3465.9 Ų65.921%0.20936%0.356CS..  trans-85.5141.817159.40000110.5P255 L259P255-T257 PolarHBondContact O-N 3.08Å; T257-L259 PolarHBondContact O-N 3.29Å; T257-L259 VanDerWaalsContact O-N 3.08Å
258Q54.4Low71.6Confident197 Ų19767.6 Ų67.692%0.92137%0.365SS*.  trans-58.6114.8172.7-74.2-177.4-3.900110.3
259L55.9Low71.4Confident83 Ų8368 Ų6844%0.43537%0.365SS..  trans-77.5137.5178.7-74.5167.5000111.2T257 L268T257-L259 PolarHBondContact O-N 3.29Å; T257-L259 VanDerWaalsContact O-N 3.08Å; L259-L268 HydrophobicContact CD1-CD2 4Å; L259-L268 HydrophobicContact CD2-CD2 4.12Å; L259-L268 HydrophobicContact CG-CD2 4.4Å
260P49.3Very low71.3Confident86 Ų8667.7 Ų67.756%0.55836%0.364SS*.  trans-63.7141.5161.4-17.930000111.2A262 R267P260-A262 VanDerWaalsContact C-N 3.29Å; P260-A262 PolarHBondContact O-N 2.71Å; P260-R267 PolarHBondContact O-NH1 3.37Å
261A48Very low71Confident118 Ų11868 Ų6898%0.97537%0.367SS*.SBendtrans-66.340.8-163.300000118.8
262A43.5Very low70.9Confident54 Ų5467.9 Ų67.945%0.44637%0.368SS..SBendtrans-137.8164.9-178.800000113.3P260 R267P260-A262 VanDerWaalsContact C-N 3.29Å; P260-A262 PolarHBondContact O-N 2.71Å; A262-R267 VanDerWaalsContact C-NH1 3.31Å; A262-R267 PolarHBondContact O-NE 3.47Å; A262-R267 PolarHBondContact O-NH1 3.08Å
263P46.8Very low71Confident111 Ų11167.9 Ų67.972%0.72137%0.368SS*.  trans-76.1158.2-142.529.4-35000116.8R267P263-R267 WeakPolarHBondContact O-CD 3.43Å; P263-R267 PolarHBondContact O-NE 2.82Å
264R45.5Very low71.1Confident254 Ų25472.6 Ų72.696%0.95838%0.384SS*.  trans-66.7152.8-165.7-62.9-179.9-177.9175.1-0115.8
265G54.7Low71.2Confident44 Ų4474.7 Ų74.745%0.45439%0.394SS..SBendtrans114.6131.1177.500000113.2R267G265-R267 PolarHBondContact O-N 2.83Å
266R58.8Low71.8Confident193 Ų19374.1 Ų74.173%0.72839%0.39SS*.SBendtrans50.5-11.6-173.4-89.9-175.4167.8164-3.2118L268 G270R266-L268 PolarHBondContact O-N 2.93Å; R266-G270 PolarHBondContact O-N 2.84Å; R266-G270 VanDerWaalsContact O-N 3.07Å
267R73.5Confident73.1Confident90 Ų9071 Ų7134%0.3437%0.371SS..Hα-helixtrans-65.6-33.2-178.5-75-173.6173.9-129.1-8.3114P260 A262 P263 G265 A271P260-R267 PolarHBondContact O-NH1 3.37Å; A262-R267 VanDerWaalsContact C-NH1 3.31Å; A262-R267 PolarHBondContact O-NE 3.47Å; A262-R267 PolarHBondContact O-NH1 3.08Å; P263-R267 WeakPolarHBondContact O-CD 3.43Å; P263-R267 PolarHBondContact O-NE 2.82Å; G265-R267 PolarHBondContact O-N 2.83Å; R267-A271 VanDerWaalsContact O-CB 3.26Å; R267-A271 WeakPolarHBondContact O-CB 3.06Å; R267-A271 PolarHBondContact O-N 3.3Å
268L87.7Confident74.8Confident36 Ų3670.6 Ų70.619%0.18837%0.374CS..Hα-helixtrans-69.5-50.8-178.1-71.3175.2000110.8Y173 L254 L259 R266 G270 A271 G272 L312Y173-L268 HydrophobicContact CD1-CD1 3.9Å; Y173-L268 HydrophobicContact CD2-CD1 4.17Å; Y173-L268 HydrophobicContact CD2-CD2 3.7Å; Y173-L268 HydrophobicContact CD2-CG 4.47Å; Y173-L268 HydrophobicContact CE1-CD1 4.25Å; Y173-L268 HydrophobicContact CE1-CD2 4.39Å; Y173-L268 HydrophobicContact CE2-CD1 4.47Å; Y173-L268 HydrophobicContact CE2-CD2 3.47Å; Y173-L268 VanDerWaalsContact CE2-CD2 3.47Å; Y173-L268 HydrophobicContact CG-CD1 3.85Å; Y173-L268 HydrophobicContact CG-CD2 4.24Å; L254-L268 HydrophobicContact CD1-CB 4.46Å; L259-L268 HydrophobicContact CD1-CD2 4Å; L259-L268 HydrophobicContact CD2-CD2 4.12Å; L259-L268 HydrophobicContact CG-CD2 4.4Å; R266-L268 PolarHBondContact O-N 2.93Å; L268-G270 PolarHBondContact O-N 3.12Å; L268-A271 PolarHBondContact O-N 2.76Å; L268-G272 PolarHBondContact O-N 3.09Å; L268-L312 HydrophobicContact CB-CD2 3.94Å; L268-L312 HydrophobicContact CD1-CD2 3.82Å
269Y92.7Very high76.9Confident13 Ų1361.4 Ų61.45%0.05133%0.33CS..Hα-helixtrans-57.6-49.1172.2-172.2-92.2000111.3D50 M250 L254 A271 G272 L273 L312 G314D50-Y269 HydrophobicContact CB-CE1 4.31Å; D50-Y269 VanDerWaalsContact OD1-CE1 3.3Å; D50-Y269 WeakPolarHBondContact OD1-CE1 3.23Å; D50-Y269 PolarHBondContact OD2-OH 3.34Å; M250-Y269 HydrophobicContact CB-CE2 3.79Å; M250-Y269 HydrophobicContact CE-CD1 4.33Å; M250-Y269 HydrophobicContact CE-CD2 3.68Å; M250-Y269 HydrophobicContact CE-CE1 4.16Å; M250-Y269 HydrophobicContact CE-CE2 3.52Å; M250-Y269 HydrophobicContact CE-CG 4.11Å; M250-Y269 VanDerWaalsContact CE-O 3.31Å; M250-Y269 WeakPolarHBondContact CE-O 3.34Å; M250-Y269 HydrophobicContact CG-CE2 4.28Å; L254-Y269 HydrophobicContact CD1-CD2 4.33Å; Y269-A271 VanDerWaalsContact C-N 3.26Å; Y269-A271 PolarHBondContact O-N 3.41Å; Y269-G272 PolarHBondContact O-N 3.38Å; Y269-G272 VanDerWaalsContact O-N 3.16Å; Y269-L273 HydrophobicContact CE1-CB 4.46Å; Y269-L273 HydrophobicContact CE1-CD2 4.09Å; Y269-L273 WeakPolarHBondContact O-CB 3.41Å; Y269-L273 PolarHBondContact O-N 2.84Å; Y269-L312 VanDerWaalsContact CD2-O 3.27Å; Y269-L312 WeakPolarHBondContact CD2-O 3.48Å; Y269-G314 VanDerWaalsContact CE2-N 3.3Å; Y269-G314 WeakPolarHBondContact OH-CA 3.47Å
270G92.8Very high78.9Confident3 Ų357.6 Ų57.63%0.03131%0.311CS..Hα-helixtrans-59.5-32.1176.600000114.1D60 R266 L268 L273 R274D60-G270 VanDerWaalsContact OD2-CA 3.32Å; D60-G270 WeakPolarHBondContact OD2-CA 3.41Å; R266-G270 PolarHBondContact O-N 2.84Å; R266-G270 VanDerWaalsContact O-N 3.07Å; L268-G270 PolarHBondContact O-N 3.12Å; G270-L273 PolarHBondContact O-N 3.32Å; G270-R274 WeakPolarHBondContact O-CG 3.09Å; G270-R274 PolarHBondContact O-N 3.32Å; G270-R274 PolarHBondContact O-NH1 2.85Å
271A91.4Very high81.3Confident9 Ų953.6 Ų53.67%0.07429%0.285CS..Hα-helixtrans-69.8-45.3174.200000112.3R267 L268 Y269 L273 R274 E275R267-A271 VanDerWaalsContact O-CB 3.26Å; R267-A271 WeakPolarHBondContact O-CB 3.06Å; R267-A271 PolarHBondContact O-N 3.3Å; L268-A271 PolarHBondContact O-N 2.76Å; Y269-A271 VanDerWaalsContact C-N 3.26Å; Y269-A271 PolarHBondContact O-N 3.41Å; A271-L273 PolarHBondContact O-N 2.84Å; A271-R274 VanDerWaalsContact CA-NH2 3.29Å; A271-R274 PolarHBondContact O-N 3.44Å; A271-E275 PolarHBondContact O-N 2.79Å
272G94.1Very high83.7Confident3 Ų351.7 Ų51.73%0.03126%0.256CS..Hα-helixtrans-61.3-36.2171.800000111.9H249 M250 L268 Y269 E275 M276H249-G272 PolarHBondContact CD2-O 3.25Å; M250-G272 VanDerWaalsContact CE-C 3.49Å; L268-G272 PolarHBondContact O-N 3.09Å; Y269-G272 PolarHBondContact O-N 3.38Å; Y269-G272 VanDerWaalsContact O-N 3.16Å; G272-E275 PolarHBondContact O-N 2.86Å; G272-M276 WeakPolarHBondContact O-CB 3.21Å; G272-M276 PolarHBondContact O-N 2.96Å
273L95.4Very high86.3Confident3 Ų349.1 Ų49.12%0.01624%0.235CC..Hα-helixtrans-67.1-41.6178.3-172.260.1000111.6M46 D50 T58 D60 T61 M250 Y269 G270 A271 M276 D277M46-L273 HydrophobicContact CE-CD1 4.12Å; D50-L273 HydrophobicContact CB-CD2 4.33Å; D50-L273 WeakPolarHBondContact O-CD2 3.49Å; T58-L273 HydrophobicContact CG2-CD2 3.93Å; D60-L273 HydrophobicContact CB-CB 4.23Å; D60-L273 HydrophobicContact CB-CD2 3.87Å; D60-L273 HydrophobicContact CB-CG 4.09Å; T61-L273 HydrophobicContact CG2-CD1 3.76Å; T61-L273 HydrophobicContact CG2-CD2 3.85Å; T61-L273 HydrophobicContact CG2-CG 3.65Å; M250-L273 HydrophobicContact CE-CB 4.06Å; M250-L273 VanDerWaalsContact CE-N 3.3Å; M250-L273 HydrophobicContact CG-CD1 4.25Å; M250-L273 HydrophobicContact SD-CB 4.27Å; M250-L273 HydrophobicContact SD-CD1 4.31Å; Y269-L273 HydrophobicContact CE1-CB 4.46Å; Y269-L273 HydrophobicContact CE1-CD2 4.09Å; Y269-L273 WeakPolarHBondContact O-CB 3.41Å; Y269-L273 PolarHBondContact O-N 2.84Å; G270-L273 PolarHBondContact O-N 3.32Å; A271-L273 PolarHBondContact O-N 2.84Å; L273-M276 HydrophobicContact CD1-CE 3.67Å; L273-M276 PolarHBondContact O-N 2.91Å; L273-D277 VanDerWaalsContact O-CB 3.26Å; L273-D277 WeakPolarHBondContact O-CB 3.37Å; L273-D277 PolarHBondContact O-N 2.76Å
274R96.3Very high88.8Confident107 Ų10744.2 Ų44.240%0.40420%0.202SC..Hα-helixtrans-64.3-37.7171.9-73.1-174-59.5-88.3-4.8112.7D60 G270 A271 G278D60-R274 HydrophobicContact CB-CG 3.72Å; D60-R274 WeakPolarHBondContact O-CA 3.45Å; D60-R274 WeakPolarHBondContact O-CG 3.45Å; D60-R274 WeakPolarHBondContact OD1-CD 3.23Å; D60-R274 IonicContact OD1-CZ 3.59Å; D60-R274 IonicContact OD1-NE 3Å; D60-R274 IonicContact OD1-NH1 3.75Å; D60-R274 PolarHBondContact OD1-NH1 3.3Å; D60-R274 IonicContact OD2-NH1 3.32Å; G270-R274 WeakPolarHBondContact O-CG 3.09Å; G270-R274 PolarHBondContact O-N 3.32Å; G270-R274 PolarHBondContact O-NH1 2.85Å; A271-R274 VanDerWaalsContact CA-NH2 3.29Å; A271-R274 PolarHBondContact O-N 3.44Å; R274-G278 PolarHBondContact O-N 3.38Å
275E96.1Very high91.3Very high48 Ų4835.3 Ų35.322%0.22417%0.173CC..Hα-helixtrans-64.9-47.1175.5-178.3179.5-123.700111.1A220 H249 A271 G272 G278 L279A220-E275 HydrophobicContact CB-CG 3.67Å; H249-E275 IonicContact CD2-OE2 3.95Å; H249-E275 IonicContact CE1-OE2 3.64Å; H249-E275 PolarHBondContact CE1-OE2 3.21Å; H249-E275 IonicContact NE2-OE2 3.72Å; H249-E275 PolarHBondContact NE2-OE2 3.4Å; A271-E275 PolarHBondContact O-N 2.79Å; G272-E275 PolarHBondContact O-N 2.86Å; E275-G278 PolarHBondContact O-N 2.64Å; E275-L279 PolarHBondContact O-N 3.23Å
276M97.6Very high93.4Very high0 Ų036.2 Ų36.20%017%0.165CC..Hα-helixtrans-58.9-48.3174.4-173.4-163.376.500111.4A43 M46 L64 L247 H249 M250 G272 L273 G278 L279 V280 F299A43-M276 HydrophobicContact CB-SD 4.01Å; M46-M276 HydrophobicContact CE-CE 4.14Å; M46-M276 HydrophobicContact SD-CE 3.8Å; M46-M276 HydrophobicContact SD-SD 4.46Å; L64-M276 HydrophobicContact CD1-CE 3.9Å; L247-M276 HydrophobicContact CD1-CG 3.61Å; L247-M276 HydrophobicContact CD1-SD 4.13Å; H249-M276 HydrophobicContact CB-CB 3.74Å; H249-M276 HydrophobicContact CB-CG 3.6Å; H249-M276 HydrophobicContact CB-SD 3.92Å; M250-M276 HydrophobicContact CG-SD 3.8Å; M250-M276 HydrophobicContact SD-CB 4.07Å; M250-M276 HydrophobicContact SD-SD 4.16Å; G272-M276 WeakPolarHBondContact O-CB 3.21Å; G272-M276 PolarHBondContact O-N 2.96Å; L273-M276 HydrophobicContact CD1-CE 3.67Å; L273-M276 PolarHBondContact O-N 2.91Å; M276-G278 VanDerWaalsContact C-N 3.33Å; M276-G278 PolarHBondContact O-N 3.04Å; M276-L279 WeakPolarHBondContact O-CB 3.33Å; M276-L279 PolarHBondContact O-N 3.3Å; M276-V280 WeakPolarHBondContact O-CG2 3.29Å; M276-V280 PolarHBondContact O-N 3.5Å; M276-F299 HydrophobicContact CE-CE2 4.43Å; M276-F299 HydrophobicContact CE-CZ 4.06Å
277D98.6Very high95.3Very high6 Ų627 Ų273%0.03213%0.13CC..Hα-helixtrans-60.5-41.6178.1-178.875.5000111.8T61 A62 N63 L64 L273 V280 G281T61-D277 VanDerWaalsContact C-CG 3.43Å; T61-D277 VanDerWaalsContact CA-CG 3.45Å; T61-D277 VanDerWaalsContact CA-OD1 3.29Å; T61-D277 WeakPolarHBondContact CA-OD1 3.49Å; A62-D277 PolarHBondContact N-OD2 3.19Å; A62-D277 VanDerWaalsContact N-OD2 3.12Å; N63-D277 WeakPolarHBondContact CB-OD1 3.42Å; N63-D277 WeakPolarHBondContact CB-OD2 3.27Å; N63-D277 PolarHBondContact N-OD1 2.96Å; N63-D277 VanDerWaalsContact N-OD1 3.09Å; N63-D277 PolarHBondContact N-OD2 2.76Å; N63-D277 PolarHBondContact ND2-O 3.44Å; N63-D277 PolarHBondContact ND2-OD2 3.12Å; L64-D277 WeakPolarHBondContact CG-OD1 3.41Å; L64-D277 PolarHBondContact N-OD1 3.23Å; L273-D277 VanDerWaalsContact O-CB 3.26Å; L273-D277 WeakPolarHBondContact O-CB 3.37Å; L273-D277 PolarHBondContact O-N 2.76Å; D277-V280 PolarHBondContact O-N 3.34Å; D277-G281 PolarHBondContact O-N 2.95Å
278G98.2Very high96.5Very high25 Ų2524.3 Ų24.326%0.25812%0.123SC..Hα-helixtrans-63.1-40.217400000113.2R274 E275 M276 G281 Q282R274-G278 PolarHBondContact O-N 3.38Å; E275-G278 PolarHBondContact O-N 2.64Å; M276-G278 VanDerWaalsContact C-N 3.33Å; M276-G278 PolarHBondContact O-N 3.04Å; G278-G281 PolarHBondContact O-N 2.91Å; G278-Q282 WeakPolarHBondContact O-CG 3.21Å; G278-Q282 PolarHBondContact O-N 2.99Å
279L98.1Very high97Very high3 Ų330.1 Ų30.12%0.01615%0.148CC..Hα-helixtrans-60.6-48.7172.4176.9167.4000110.7A220 A224 L247 E275 M276 G281 Q282 I283A220-L279 HydrophobicContact CB-CD1 4.23Å; A220-L279 VanDerWaalsContact O-CD1 3.3Å; A220-L279 WeakPolarHBondContact O-CD1 3.43Å; A224-L279 HydrophobicContact CB-CG 4.17Å; L247-L279 HydrophobicContact CD2-CD1 3.92Å; L247-L279 HydrophobicContact CD2-CD2 3.56Å; L247-L279 HydrophobicContact CD2-CG 4.46Å; E275-L279 PolarHBondContact O-N 3.23Å; M276-L279 WeakPolarHBondContact O-CB 3.33Å; M276-L279 PolarHBondContact O-N 3.3Å; L279-G281 VanDerWaalsContact C-N 3.31Å; L279-G281 PolarHBondContact O-N 3.03Å; L279-Q282 PolarHBondContact O-N 3.35Å; L279-I283 HydrophobicContact CD2-CD1 3.52Å; L279-I283 HydrophobicContact CD2-CG1 4.34Å; L279-I283 WeakPolarHBondContact O-CG1 3.38Å; L279-I283 PolarHBondContact O-N 2.83Å; L279-I283 VanDerWaalsContact O-N 3.14Å
280V98.8Very high97.1Very high3 Ų331.5 Ų31.52%0.01816%0.158CC..Hα-helixtrans-62.1-41.3178.5174.60000111I41 L64 L247 M276 D277 Q282 I283 K284 F299I41-V280 HydrophobicContact CD1-CG1 3.93Å; I41-V280 HydrophobicContact CD1-CG2 4.45Å; I41-V280 HydrophobicContact CG2-CG2 4.08Å; L64-V280 HydrophobicContact CD2-CG1 3.81Å; L64-V280 HydrophobicContact CG-CG1 4.46Å; L247-V280 HydrophobicContact CD1-CG2 4.15Å; M276-V280 WeakPolarHBondContact O-CG2 3.29Å; M276-V280 PolarHBondContact O-N 3.5Å; D277-V280 PolarHBondContact O-N 3.34Å; V280-Q282 PolarHBondContact O-N 2.93Å; V280-I283 PolarHBondContact O-N 3.2Å; V280-K284 PolarHBondContact O-N 2.82Å; V280-F299 HydrophobicContact CG2-CD2 4.35Å; V280-F299 HydrophobicContact CG2-CE2 4.12Å
281G98.7Very high97.2Very high2 Ų232 Ų322%0.02116%0.162CC..Hα-helixtrans-55.5-48.7173.200000112.4D277 G278 L279 I283 K284 D285D277-G281 PolarHBondContact O-N 2.95Å; G278-G281 PolarHBondContact O-N 2.91Å; L279-G281 VanDerWaalsContact C-N 3.31Å; L279-G281 PolarHBondContact O-N 3.03Å; G281-I283 VanDerWaalsContact C-N 3.32Å; G281-I283 PolarHBondContact O-N 3.33Å; G281-K284 PolarHBondContact O-N 3.1Å; G281-D285 WeakPolarHBondContact O-CB 3.4Å; G281-D285 VanDerWaalsContact O-CG 3.3Å; G281-D285 PolarHBondContact O-N 2.8Å
282Q98.8Very high97.4Very high79 Ų7935.8 Ų35.837%0.36918%0.177SC..Hα-helixtrans-60.4-39.5177.6-72.9179.369.100113A224 G278 L279 V280 K286A224-Q282 HydrophobicContact CB-CB 4.48Å; G278-Q282 WeakPolarHBondContact O-CG 3.21Å; G278-Q282 PolarHBondContact O-N 2.99Å; L279-Q282 PolarHBondContact O-N 3.35Å; V280-Q282 PolarHBondContact O-N 2.93Å; Q282-K286 WeakPolarHBondContact O-CB 3.38Å; Q282-K286 PolarHBondContact O-N 3.16Å
283I98.8Very high97.4Very high0 Ų041.6 Ų41.60%021%0.207CC..Hα-helixtrans-66.3-48.9177.1-66.3176000110.4V39 I41 A227 I231 V245 L279 V280 G281 K286 V287V39-I283 HydrophobicContact CG1-CG2 3.96Å; I41-I283 HydrophobicContact CD1-CG2 4.23Å; A227-I283 HydrophobicContact CB-CD1 3.78Å; A227-I283 HydrophobicContact CB-CG1 3.86Å; I231-I283 HydrophobicContact CD1-CG2 3.98Å; V245-I283 HydrophobicContact CG1-CD1 3.89Å; V245-I283 HydrophobicContact CG2-CD1 4.13Å; L279-I283 HydrophobicContact CD2-CD1 3.52Å; L279-I283 HydrophobicContact CD2-CG1 4.34Å; L279-I283 WeakPolarHBondContact O-CG1 3.38Å; L279-I283 PolarHBondContact O-N 2.83Å; L279-I283 VanDerWaalsContact O-N 3.14Å; V280-I283 PolarHBondContact O-N 3.2Å; G281-I283 VanDerWaalsContact C-N 3.32Å; G281-I283 PolarHBondContact O-N 3.33Å; I283-K286 PolarHBondContact O-N 2.92Å; I283-V287 PolarHBondContact O-N 2.82Å
284K98.6Very high97.5Very high8 Ų842.9 Ų42.94%0.03521%0.214CC..Hα-helixtrans-60.7-46.6178-179.4179.5177.8-62.50111.3M67 E70 V280 G281 K286 V287 D288 L297 Y348M67-K284 HydrophobicContact CB-CD 4.14Å; M67-K284 HydrophobicContact CG-CD 4.22Å; E70-K284 VanDerWaalsContact OE2-CE 3.27Å; E70-K284 WeakPolarHBondContact OE2-CE 3.34Å; E70-K284 IonicContact OE2-NZ 3.98Å; E70-K284 PolarHBondContact OE2-NZ 3.47Å; V280-K284 PolarHBondContact O-N 2.82Å; G281-K284 PolarHBondContact O-N 3.1Å; K284-K286 VanDerWaalsContact C-N 3.31Å; K284-K286 PolarHBondContact O-N 3.34Å; K284-V287 WeakPolarHBondContact O-CB 3.4Å; K284-V287 PolarHBondContact O-N 3.28Å; K284-V287 VanDerWaalsContact O-N 3.12Å; K284-D288 IonicContact NZ-OD2 3.54Å; K284-D288 PolarHBondContact NZ-OD2 2.75Å; K284-D288 PolarHBondContact O-N 3.3Å; K284-L297 HydrophobicContact CB-CD2 3.95Å; K284-L297 HydrophobicContact CG-CD2 3.89Å; K284-Y348 HydrophobicContact CG-CE1 4.43Å; K284-Y348 PolarHBondContact NZ-OH 3.3Å
285D98.7Very high97.6Very high66 Ų6637.8 Ų37.835%0.35320%0.195SC..Hα-helixtrans-59.3-43.8177.2-76.3-13.7000110.6G281 V287 D288 H289G281-D285 WeakPolarHBondContact O-CB 3.4Å; G281-D285 VanDerWaalsContact O-CG 3.3Å; G281-D285 PolarHBondContact O-N 2.8Å; D285-V287 VanDerWaalsContact C-N 3.32Å; D285-V287 PolarHBondContact O-N 2.94Å; D285-D288 PolarHBondContact O-N 3.04Å; D285-H289 PolarHBondContact O-N 3.46Å; D285-H289 PolarHBondContact O-ND1 3.5Å
286K98.7Very high97.7Very high64 Ų6435.7 Ų35.728%0.27819%0.185SC..Hα-helixtrans-60.7-41.4176178.560.266177.80111.9T228 I231 Q282 I283 K284 H289 T290T228-K286 HydrophobicContact CG2-CB 3.7Å; T228-K286 HydrophobicContact CG2-CG 4.01Å; I231-K286 HydrophobicContact CB-CG 4Å; I231-K286 HydrophobicContact CD1-CG 4.27Å; I231-K286 HydrophobicContact CG2-CG 3.86Å; Q282-K286 WeakPolarHBondContact O-CB 3.38Å; Q282-K286 PolarHBondContact O-N 3.16Å; I283-K286 PolarHBondContact O-N 2.92Å; K284-K286 VanDerWaalsContact C-N 3.31Å; K284-K286 PolarHBondContact O-N 3.34Å; K286-H289 PolarHBondContact O-N 2.97Å; K286-T290 HydrophobicContact CD-CG2 3.71Å; K286-T290 HydrophobicContact CG-CG2 4.48Å; K286-T290 WeakPolarHBondContact O-CB 3.37Å; K286-T290 WeakPolarHBondContact O-CG2 3.42Å; K286-T290 PolarHBondContact O-N 3.21Å; K286-T290 VanDerWaalsContact O-N 3.16Å; K286-T290 PolarHBondContact O-OG1 2.83Å
287V98.4Very high97.7Very high0 Ų035.7 Ų35.70%019%0.185CC..Hα-helixtrans-60.9-48.6173.7169.60000110.9V39 I231 I283 K284 D285 H289 T290 A291 K292 T295 L297V39-V287 HydrophobicContact CG2-CG2 4.02Å; I231-V287 HydrophobicContact CD1-CG2 3.84Å; I231-V287 HydrophobicContact CG1-CG2 4.49Å; I231-V287 HydrophobicContact CG2-CG2 4.34Å; I283-V287 PolarHBondContact O-N 2.82Å; K284-V287 WeakPolarHBondContact O-CB 3.4Å; K284-V287 PolarHBondContact O-N 3.28Å; K284-V287 VanDerWaalsContact O-N 3.12Å; D285-V287 VanDerWaalsContact C-N 3.32Å; D285-V287 PolarHBondContact O-N 2.94Å; V287-H289 PolarHBondContact O-N 3.4Å; V287-T290 PolarHBondContact O-N 3.42Å; V287-T290 PolarHBondContact O-OG1 3.34Å; V287-A291 CarbonylContact O-C 3.4Å; V287-A291 PolarHBondContact O-N 3.04Å; V287-K292 PolarHBondContact O-N 2.98Å; V287-K292 VanDerWaalsContact O-N 3.09Å; V287-T295 VanDerWaalsContact CG1-CB 3.48Å; V287-T295 HydrophobicContact CG1-CG2 3.61Å; V287-T295 HydrophobicContact CG2-CG2 4.19Å; V287-L297 HydrophobicContact CB-CD1 4.28Å; V287-L297 HydrophobicContact CG1-CD1 3.82Å; V287-L297 HydrophobicContact CG2-CD1 4.13Å
288D98.1Very high97.8Very high33 Ų3335.5 Ų35.518%0.17618%0.184CC..Hα-helixtrans-59.9-31.8-178.6-78.5-21.7000112.3K284 D285 K292 Y348K284-D288 IonicContact NZ-OD2 3.54Å; K284-D288 PolarHBondContact NZ-OD2 2.75Å; K284-D288 PolarHBondContact O-N 3.3Å; D285-D288 PolarHBondContact O-N 3.04Å; D288-K292 HydrophobicContact CB-CD 4.33Å; D288-K292 WeakPolarHBondContact O-CB 3.31Å; D288-K292 WeakPolarHBondContact OD1-CG 3.4Å; D288-Y348 VanDerWaalsContact CG-OH 3.24Å; D288-Y348 WeakPolarHBondContact OD1-CE1 3.44Å; D288-Y348 PolarHBondContact OD1-OH 3.2Å; D288-Y348 PolarHBondContact OD2-OH 3.2Å
289H97.8Very high97.8Very high158 Ų15834.3 Ų34.373%0.73117%0.172SC*.Hα-helixtrans-82.8-20.1176.5-7192.3000114.5D285 K286 V287D285-H289 PolarHBondContact O-N 3.46Å; D285-H289 PolarHBondContact O-ND1 3.5Å; K286-H289 PolarHBondContact O-N 2.97Å; V287-H289 PolarHBondContact O-N 3.4Å
290T96.1Very high97.8Very high42 Ų4234.1 Ų34.126%0.25817%0.171SC..Hα-helixtrans-114.3-39.9-169.553.80000114.2I231 K286 V287I231-T290 WeakPolarHBondContact CG2-OG1 3.3Å; K286-T290 HydrophobicContact CD-CG2 3.71Å; K286-T290 HydrophobicContact CG-CG2 4.48Å; K286-T290 WeakPolarHBondContact O-CB 3.37Å; K286-T290 WeakPolarHBondContact O-CG2 3.42Å; K286-T290 PolarHBondContact O-N 3.21Å; K286-T290 VanDerWaalsContact O-N 3.16Å; K286-T290 PolarHBondContact O-OG1 2.83Å; V287-T290 PolarHBondContact O-N 3.42Å; V287-T290 PolarHBondContact O-OG1 3.34Å
291A94.6Very high97.8Very high14 Ų1434 Ų3412%0.11617%0.17CC..THydrogen-bonded Turntrans-15432.9-170.200000113.3V287 D293 N294 T295V287-A291 CarbonylContact O-C 3.4Å; V287-A291 PolarHBondContact O-N 3.04Å; A291-D293 PolarHBondContact O-N 3.3Å; A291-N294 CarbonylContact O-C 3.39Å; A291-N294 PolarHBondContact O-N 2.61Å; A291-N294 VanDerWaalsContact O-N 3.13Å; A291-T295 WeakPolarHBondContact CB-OG1 3.15Å; A291-T295 WeakPolarHBondContact O-CB 3.18Å; A291-T295 PolarHBondContact O-N 3.46Å; A291-T295 PolarHBondContact O-OG1 3.45Å
292K95.8Very high97.8Very high88 Ų8833.9 Ų33.938%0.38317%0.169SC..G310 helixtrans-42-58.7-174-172.7167.9-177.81730114.8V287 D288 N294 T295 Y348 P350V287-K292 PolarHBondContact O-N 2.98Å; V287-K292 VanDerWaalsContact O-N 3.09Å; D288-K292 HydrophobicContact CB-CD 4.33Å; D288-K292 WeakPolarHBondContact O-CB 3.31Å; D288-K292 WeakPolarHBondContact OD1-CG 3.4Å; K292-N294 PolarHBondContact O-N 3.19Å; K292-T295 PolarHBondContact O-N 3.08Å; K292-Y348 WeakPolarHBondContact CE-OH 3.34Å; K292-P350 HydrophobicContact CD-CG 4.34Å; K292-P350 HydrophobicContact CG-CB 4.2Å; K292-P350 HydrophobicContact CG-CG 3.77Å
293D93.8Very high97.8Very high124 Ų12430.1 Ų30.166%0.66315%0.151SC*.G310 helixtrans-74.7-13.6-170.4-55.9-36.6000113.5A291 W349A291-D293 PolarHBondContact O-N 3.3Å; D293-W349 PolarHBondContact O-NE1 3.13Å
294N96.2Very high97.8Very high30 Ų3030.1 Ų30.116%0.1615%0.151CC..G310 helixtrans-11514.8-177.1-165.667000112.7K35 P36 N37 A291 K292K35-N294 PolarHBondContact O-ND2 2.86Å; P36-N294 CarbonylContact C-O 3.6Å; P36-N294 WeakPolarHBondContact CA-O 3.17Å; N37-N294 PolarHBondContact N-O 3.02Å; N37-N294 PolarHBondContact ND2-O 2.72Å; A291-N294 CarbonylContact O-C 3.39Å; A291-N294 PolarHBondContact O-N 2.61Å; A291-N294 VanDerWaalsContact O-N 3.13Å; K292-N294 PolarHBondContact O-N 3.19Å
295T98.4Very high97.8Very high0 Ų029.9 Ų29.90%015%0.15CC..EExtended strand (participates in β ladder)trans-125.7124.6-177.4-50.20000110.7N37 V39 F241 V287 A291 K292 L297N37-T295 HydrophobicContact CB-CG2 3.86Å; N37-T295 PolarHBondContact ND2-OG1 3.37Å; N37-T295 VanDerWaalsContact ND2-OG1 3.12Å; N37-T295 WeakPolarHBondContact O-CA 3.21Å; V39-T295 HydrophobicContact CG2-CG2 3.84Å; F241-T295 HydrophobicContact CZ-CG2 4.31Å; V287-T295 VanDerWaalsContact CG1-CB 3.48Å; V287-T295 HydrophobicContact CG1-CG2 3.61Å; V287-T295 HydrophobicContact CG2-CG2 4.19Å; A291-T295 WeakPolarHBondContact CB-OG1 3.15Å; A291-T295 WeakPolarHBondContact O-CB 3.18Å; A291-T295 PolarHBondContact O-N 3.46Å; A291-T295 PolarHBondContact O-OG1 3.45Å; K292-T295 PolarHBondContact O-N 3.08Å; T295-L297 HydrophobicContact CG2-CD1 3.59Å
296F98.8Very high97.7Very high4 Ų428.6 Ų28.62%0.01814%0.141CC..EExtended strand (participates in β ladder)trans-93.8125.2171175.5-134.8000109.9N37 F38 V39 W298 A347 W349 V353 L375 L395N37-F296 PolarHBondContact O-N 3.28Å; F38-F296 HydrophobicContact CD1-CB 4.08Å; F38-F296 AromaticContact CD1-CD1 3.95Å; F38-F296 HydrophobicContact CD1-CD1 3.95Å; F38-F296 HydrophobicContact CE1-CB 4.45Å; F38-F296 HydrophobicContact CE1-CD1 4.26Å; V39-F296 PolarHBondContact N-O 2.92Å; F296-W298 HydrophobicContact CE1-CB 4.26Å; F296-W298 HydrophobicContact CE1-CD2 4.11Å; F296-W298 AromaticContact CE1-CE3 3.37Å; F296-W298 HydrophobicContact CE1-CE3 3.37Å; F296-W298 AromaticContact CE1-CZ3 3.95Å; F296-W298 HydrophobicContact CE1-CZ3 3.95Å; F296-W298 HydrophobicContact CZ-CB 4.07Å; F296-W298 AromaticContact CZ-CD2 3.81Å; F296-W298 HydrophobicContact CZ-CD2 3.81Å; F296-W298 AromaticContact CZ-CE3 3.47Å; F296-W298 HydrophobicContact CZ-CE3 3.47Å; F296-W298 VanDerWaalsContact CZ-CE3 3.47Å; F296-W298 HydrophobicContact CZ-CG 4.13Å; F296-W298 HydrophobicContact CZ-CZ3 4.07Å; F296-A347 HydrophobicContact CE2-CB 3.87Å; F296-A347 HydrophobicContact CZ-CB 4.31Å; F296-W349 HydrophobicContact CB-CD2 4Å; F296-W349 HydrophobicContact CB-CE3 3.66Å; F296-W349 HydrophobicContact CB-CG 4.45Å; F296-W349 HydrophobicContact CB-CZ3 4.12Å; F296-W349 HydrophobicContact CD2-CB 4.1Å; F296-W349 HydrophobicContact CD2-CE3 4.14Å; F296-W349 HydrophobicContact CG-CE3 4.03Å; F296-V353 HydrophobicContact CE2-CG2 4.38Å; F296-L375 HydrophobicContact CD1-CD1 4.18Å; F296-L375 HydrophobicContact CE1-CD1 4.39Å; F296-L395 HydrophobicContact CE1-CD1 4.08Å; F296-L395 HydrophobicContact CE2-CD1 4.41Å; F296-L395 HydrophobicContact CE2-CD2 4.11Å; F296-L395 HydrophobicContact CZ-CD1 3.68Å; F296-L395 HydrophobicContact CZ-CD2 3.79Å; F296-L395 HydrophobicContact CZ-CG 4.41Å
297L98.9Very high97.6Very high1 Ų126.8 Ų26.81%0.00514%0.138CC..EExtended strand (participates in β ladder)trans-106.6130.8173.8-85.261.3000109.8V39 M67 K284 V287 T295 A347 Y348V39-L297 HydrophobicContact CB-CD1 4Å; V39-L297 HydrophobicContact CB-CG 3.95Å; V39-L297 HydrophobicContact CG1-CG 4.34Å; V39-L297 HydrophobicContact CG2-CD1 4.24Å; V39-L297 VanDerWaalsContact O-CA 3.31Å; V39-L297 WeakPolarHBondContact O-CA 3.42Å; M67-L297 HydrophobicContact CE-CB 3.7Å; K284-L297 HydrophobicContact CB-CD2 3.95Å; K284-L297 HydrophobicContact CG-CD2 3.89Å; V287-L297 HydrophobicContact CB-CD1 4.28Å; V287-L297 HydrophobicContact CG1-CD1 3.82Å; V287-L297 HydrophobicContact CG2-CD1 4.13Å; T295-L297 HydrophobicContact CG2-CD1 3.59Å; L297-A347 WeakPolarHBondContact O-CA 3.4Å; L297-Y348 HydrophobicContact CB-CD1 4.19Å; L297-Y348 HydrophobicContact CD1-CD1 4.42Å; L297-Y348 HydrophobicContact CD2-CD1 4.09Å; L297-Y348 HydrophobicContact CG-CD1 4.46Å; L297-Y348 PolarHBondContact N-O 2.84Å; L297-Y348 PolarHBondContact O-N 2.68Å
298W98.9Very high97.5Very high1 Ų129 Ų290%0.00415%0.148CC..EExtended strand (participates in β ladder)trans-127.3116172.7-154.9-25.6000109.6V39 I40 I41 F77 F296 L346 I368 T371 V391 L395V39-W298 PolarHBondContact O-N 3Å; I40-W298 CarbonylContact C-O 3.55Å; I40-W298 WeakPolarHBondContact CA-O 3.49Å; I41-W298 PolarHBondContact N-O 2.7Å; F77-W298 AromaticContact CE2-CZ2 3.81Å; F77-W298 HydrophobicContact CE2-CZ2 3.81Å; F77-W298 HydrophobicContact CZ-CZ2 4.3Å; F296-W298 HydrophobicContact CE1-CB 4.26Å; F296-W298 HydrophobicContact CE1-CD2 4.11Å; F296-W298 AromaticContact CE1-CE3 3.37Å; F296-W298 HydrophobicContact CE1-CE3 3.37Å; F296-W298 AromaticContact CE1-CZ3 3.95Å; F296-W298 HydrophobicContact CE1-CZ3 3.95Å; F296-W298 HydrophobicContact CZ-CB 4.07Å; F296-W298 AromaticContact CZ-CD2 3.81Å; F296-W298 HydrophobicContact CZ-CD2 3.81Å; F296-W298 AromaticContact CZ-CE3 3.47Å; F296-W298 HydrophobicContact CZ-CE3 3.47Å; F296-W298 VanDerWaalsContact CZ-CE3 3.47Å; F296-W298 HydrophobicContact CZ-CG 4.13Å; F296-W298 HydrophobicContact CZ-CZ3 4.07Å; W298-L346 WeakPolarHBondContact CA-O 3.47Å; W298-I368 HydrophobicContact CD2-CD1 4.45Å; W298-I368 HydrophobicContact CD2-CG1 4.04Å; W298-I368 HydrophobicContact CE3-CG1 3.9Å; W298-I368 HydrophobicContact CE3-CG2 4.49Å; W298-I368 HydrophobicContact CH2-CG1 4.15Å; W298-I368 HydrophobicContact CZ2-CG1 4.25Å; W298-I368 HydrophobicContact CZ3-CB 4.44Å; W298-I368 HydrophobicContact CZ3-CG1 3.98Å; W298-T371 HydrophobicContact CZ3-CG2 4.05Å; W298-V391 HydrophobicContact CH2-CG2 3.71Å; W298-V391 HydrophobicContact CZ2-CG2 4.47Å; W298-L395 HydrophobicContact CH2-CD1 4.26Å; W298-L395 HydrophobicContact CZ3-CD1 4.12Å
299F98.9Very high97.3Very high0 Ų028.1 Ų28.10%014%0.143CC..EExtended strand (participates in β ladder)trans-103.6136174.3175.5-90.1000110I41 A43 M46 L64 M67 M276 V280 P344 A345 L346I41-F299 HydrophobicContact CB-CD2 3.94Å; I41-F299 HydrophobicContact CG2-CD2 3.69Å; I41-F299 HydrophobicContact CG2-CE2 4.08Å; I41-F299 CarbonylContact O-C 3.56Å; I41-F299 WeakPolarHBondContact O-CA 3.16Å; A43-F299 HydrophobicContact CB-CE2 4.39Å; A43-F299 HydrophobicContact CB-CZ 4.13Å; M46-F299 HydrophobicContact CE-CE1 4.4Å; M46-F299 HydrophobicContact CE-CZ 4.36Å; M46-F299 HydrophobicContact SD-CE1 3.92Å; M46-F299 HydrophobicContact SD-CZ 3.61Å; L64-F299 HydrophobicContact CD1-CE1 3.98Å; L64-F299 HydrophobicContact CD1-CE2 4.14Å; L64-F299 HydrophobicContact CD1-CZ 3.68Å; L64-F299 HydrophobicContact CD2-CB 4.36Å; L64-F299 HydrophobicContact CD2-CD1 3.74Å; L64-F299 HydrophobicContact CD2-CD2 3.64Å; L64-F299 HydrophobicContact CD2-CE1 3.87Å; L64-F299 HydrophobicContact CD2-CE2 3.77Å; L64-F299 HydrophobicContact CD2-CG 3.63Å; L64-F299 HydrophobicContact CD2-CZ 3.88Å; L64-F299 HydrophobicContact CG-CZ 4.47Å; M67-F299 HydrophobicContact CE-CB 4.25Å; M67-F299 HydrophobicContact SD-CB 4.4Å; M276-F299 HydrophobicContact CE-CE2 4.43Å; M276-F299 HydrophobicContact CE-CZ 4.06Å; V280-F299 HydrophobicContact CG2-CD2 4.35Å; V280-F299 HydrophobicContact CG2-CE2 4.12Å; F299-P344 HydrophobicContact CE1-CG 4.33Å; F299-A345 CarbonylContact O-C 3.56Å; F299-A345 VanDerWaalsContact O-CA 3.24Å; F299-A345 WeakPolarHBondContact O-CA 3.46Å; F299-L346 HydrophobicContact CB-CB 4.29Å; F299-L346 HydrophobicContact CD1-CD1 4.48Å; F299-L346 PolarHBondContact N-O 3.13Å; F299-L346 PolarHBondContact O-N 2.64Å
300T98.9Very high97.2Very high0 Ų022 Ų220%012%0.117CC..EExtended strand (participates in β ladder)trans-156.8173.7171.7-172.60000112.6I41 L42 A43 F77 V343 P344 V365 I368I41-T300 PolarHBondContact O-N 3.35Å; L42-T300 CarbonylContact C-O 3.56Å; L42-T300 WeakPolarHBondContact CA-O 3.4Å; L42-T300 HydrophobicContact CD1-CG2 3.64Å; A43-T300 PolarHBondContact N-O 2.94Å; F77-T300 HydrophobicContact CE1-CG2 4.31Å; F77-T300 WeakPolarHBondContact CE1-OG1 3.49Å; T300-V343 WeakPolarHBondContact OG1-CG2 3.43Å; T300-P344 WeakPolarHBondContact CA-O 3.46Å; T300-P344 PolarHBondContact OG1-O 3.09Å; T300-V365 HydrophobicContact CG2-CG2 4.17Å; T300-I368 HydrophobicContact CG2-CD1 4.12Å
301G98.3Very high97Very high0 Ų025.8 Ų25.80%013%0.132CC..EExtended strand (participates in β ladder)trans-99.6158.7166.900000113.7A43 P344A43-G301 CarbonylContact O-C 3.24Å; A43-G301 WeakPolarHBondContact O-CA 3.38Å; G301-P344 PolarHBondContact N-O 3.44Å
302D98.4Very high97Very high0 Ų025.6 Ų25.60%013%0.129CC..SBendtrans-85.9-29176.171.6-14.1000114L42 A43 D44 D45 A79 S87 R88L42-D302 HydrophobicContact CD1-CB 4.01Å; L42-D302 HydrophobicContact CD2-CB 3.88Å; L42-D302 HydrophobicContact CG-CB 3.99Å; A43-D302 PolarHBondContact O-N 3.38Å; D44-D302 WeakPolarHBondContact CA-OD1 3.23Å; D44-D302 VanDerWaalsContact OD1-OD2 3.08Å; D45-D302 PolarHBondContact N-OD1 3.12Å; D45-D302 VanDerWaalsContact N-OD1 3.1Å; A79-D302 WeakPolarHBondContact CB-O 3.41Å; S87-D302 WeakPolarHBondContact CB-O 3.31Å; S87-D302 PolarHBondContact OG-O 2.91Å; R88-D302 IonicContact CZ-OD2 2.66Å; R88-D302 IonicContact NE-OD2 3.82Å; R88-D302 PolarHBondContact NE-OD2 3.43Å; R88-D302 IonicContact NH2-OD2 2.9Å; R88-D302 PolarHBondContact NH2-OD2 3.46Å
303N98.8Very high97Very high0 Ų022.3 Ų22.30%012%0.118CC..SBendtrans-162.9175.2171.449.1-119.9000110.5D45 M46 T83 C84D45-N303 PolarHBondContact OD1-ND2 3.21Å; M46-N303 VanDerWaalsContact O-O 3.13Å; T83-N303 WeakPolarHBondContact CA-OD1 3.36Å; C84-N303 PolarHBondContact N-OD1 3.37Å; C84-N303 VanDerWaalsContact N-OD1 3.17Å
304G98.4Very high97.1Very high0 Ų017.2 Ų17.20%010%0.095CC..  trans-65.9178173.700000114G339 G340G304-G339 WeakPolarHBondContact CA-O 3.33Å; G304-G340 PolarHBondContact N-O 3.39Å
305P98.1Very high97.1Very high2 Ų216.8 Ų16.81%0.0139%0.094CC..  trans-75.3148.9-171.931.3-33.5000112.7D45 A307 G314 V316 A332 K333 G339D45-P305 WeakPolarHBondContact O-CA 3.13Å; P305-A307 PolarHBondContact O-N 2.81Å; P305-G314 VanDerWaalsContact CB-C 3.41Å; P305-G314 WeakPolarHBondContact CB-O 3.29Å; P305-V316 HydrophobicContact CG-CG1 3.6Å; P305-A332 HydrophobicContact CG-CB 4.11Å; P305-A332 WeakPolarHBondContact O-CB 3.24Å; P305-K333 WeakPolarHBondContact O-CB 3.08Å; P305-K333 PolarHBondContact O-N 3.2Å; P305-K333 VanDerWaalsContact O-N 3.13Å; P305-G339 WeakPolarHBondContact CD-O 3.4Å
306W97.3Very high97.1Very high40 Ų4018 Ų1815%0.15210%0.102CC..  trans-84.480.2179.4-164.72000112H251 V252 E308 K309 A313 K333H251-W306 AromaticContact CE1-CE3 3.9Å; H251-W306 AromaticContact CE1-CZ3 3.43Å; H251-W306 VanDerWaalsContact CE1-CZ3 3.43Å; H251-W306 WeakPolarHBondContact CE1-CZ3 3.3Å; H251-W306 AromaticContact NE2-CE3 3.91Å; H251-W306 AromaticContact NE2-CZ3 3.74Å; V252-W306 HydrophobicContact CG2-CE3 3.92Å; V252-W306 HydrophobicContact CG2-CZ3 3.89Å; W306-E308 PolarHBondContact NE1-OE2 3.49Å; W306-E308 VanDerWaalsContact NE1-OE2 3.08Å; W306-E308 PolarHBondContact O-N 3.42Å; W306-K309 HydrophobicContact CB-CG 4.16Å; W306-K309 HydrophobicContact CD2-CD 4.35Å; W306-K309 HydrophobicContact CD2-CG 3.79Å; W306-K309 HydrophobicContact CE3-CD 4.39Å; W306-K309 HydrophobicContact CE3-CG 3.93Å; W306-K309 HydrophobicContact CG-CG 3.9Å; W306-K309 VanDerWaalsContact CH2-CE 3.42Å; W306-K309 VanDerWaalsContact CZ3-CE 3.45Å; W306-K309 WeakPolarHBondContact O-CB 3.2Å; W306-K309 PolarHBondContact O-N 3.03Å; W306-A313 WeakPolarHBondContact O-CB 3.09Å; W306-K333 HydrophobicContact CB-CD 3.75Å; W306-K333 HydrophobicContact CD2-CD 4.36Å; W306-K333 HydrophobicContact CG-CD 3.86Å
307A96.6Very high97Very high26 Ų2618.3 Ų18.322%0.21511%0.106CC..G310 helixtrans-55.7-25.3-171.600000115.9P305 K309 C310 S330 A332 C440P305-A307 PolarHBondContact O-N 2.81Å; A307-K309 PolarHBondContact O-N 3.01Å; A307-K309 VanDerWaalsContact O-N 3.16Å; A307-C310 PolarHBondContact O-N 3.46Å; A307-C310 VanDerWaalsContact O-N 3.16Å; A307-S330 WeakPolarHBondContact CB-OG 3.43Å; A307-A332 HydrophobicContact CB-CB 4.1Å; A307-C440 PolarHBondContact O-N 2.89Å
308E95.6Very high96.9Very high47 Ų4719.5 Ų19.522%0.2212%0.116CC..G310 helixtrans-56.1-25.4172.1-171.9178.417600112.5W306 C310 R438W306-E308 PolarHBondContact NE1-OE2 3.49Å; W306-E308 VanDerWaalsContact NE1-OE2 3.08Å; W306-E308 PolarHBondContact O-N 3.42Å; E308-C310 PolarHBondContact O-N 3.2Å; E308-R438 HydrophobicContact CG-CB 4.39Å; E308-R438 HydrophobicContact CG-CG 4.21Å; E308-R438 WeakPolarHBondContact OE1-CD 3.41Å; E308-R438 IonicContact OE1-NE 3.79Å
309K95.3Very high96.9Very high14 Ų1419.9 Ų19.96%0.06112%0.118CC..G310 helixtrans-83.711.5-179.2-52.9-58.7-177172.90114N174 H175 V252 W306 A307 E311 L312 A313N174-K309 PolarHBondContact OD1-NZ 3.3Å; H175-K309 VanDerWaalsContact O-CD 3.24Å; H175-K309 WeakPolarHBondContact O-CD 3.42Å; H175-K309 PolarHBondContact O-NZ 3.4Å; V252-K309 HydrophobicContact CG1-CB 4.02Å; V252-K309 HydrophobicContact CG1-CG 4.09Å; V252-K309 HydrophobicContact CG2-CB 4.5Å; V252-K309 HydrophobicContact CG2-CD 3.73Å; V252-K309 HydrophobicContact CG2-CG 3.66Å; W306-K309 HydrophobicContact CB-CG 4.16Å; W306-K309 HydrophobicContact CD2-CD 4.35Å; W306-K309 HydrophobicContact CD2-CG 3.79Å; W306-K309 HydrophobicContact CE3-CD 4.39Å; W306-K309 HydrophobicContact CE3-CG 3.93Å; W306-K309 HydrophobicContact CG-CG 3.9Å; W306-K309 VanDerWaalsContact CH2-CE 3.42Å; W306-K309 VanDerWaalsContact CZ3-CE 3.45Å; W306-K309 WeakPolarHBondContact O-CB 3.2Å; W306-K309 PolarHBondContact O-N 3.03Å; A307-K309 PolarHBondContact O-N 3.01Å; A307-K309 VanDerWaalsContact O-N 3.16Å; K309-E311 PolarHBondContact O-N 2.86Å; K309-L312 HydrophobicContact CB-CB 4.38Å; K309-L312 WeakPolarHBondContact O-CB 3.29Å; K309-L312 PolarHBondContact O-N 2.63Å; K309-A313 HydrophobicContact CB-CB 4.32Å
310C94.3Very high96.8Very high29 Ų2922.6 Ų22.620%0.19613%0.134CC..G310 helixtrans54.6-128171.1-61.60000112.4H175 A307 E308 L312 A313 C440H175-C310 PolarHBondContact CD2-SG 2.96Å; A307-C310 PolarHBondContact O-N 3.46Å; A307-C310 VanDerWaalsContact O-N 3.16Å; E308-C310 PolarHBondContact O-N 3.2Å; C310-L312 PolarHBondContact O-N 3.48Å; C310-L312 VanDerWaalsContact O-N 3.13Å; C310-A313 WeakPolarHBondContact O-CB 3.35Å; C310-A313 PolarHBondContact O-N 2.88Å; C310-C440 VanDerWaalsContact CA-SG 3.53Å; C310-C440 HydrophobicContact CB-CB 3.89Å; C310-C440 WeakPolarHBondContact CB-SG 3.29Å; C310-C440 VanDerWaalsContact SG-CA 3.52Å; C310-C440 WeakPolarHBondContact SG-CB 3.33Å; C310-C440 CovalentContact SG-SG 2.02Å; C310-C440 PolarHBondContact SG-SG 3.4Å
311E93.1Very high96.8Very high121 Ų12122.6 Ų22.657%0.56513%0.134SC*.G310 helixtrans-66.8-6.1179.464.4-161-149.600115.2K309K309-E311 PolarHBondContact O-N 2.86Å
312L94.5Very high96.8Very high10 Ų1024.1 Ų24.15%0.05214%0.143CC..G310 helixtrans-96.90.4173.1-50174.6000112.3N174 H175 V252 L254 L268 Y269 K309 C310N174-L312 VanDerWaalsContact C-CD1 3.4Å; H175-L312 HydrophobicContact CB-CD1 4.23Å; V252-L312 HydrophobicContact CG1-CB 3.86Å; L254-L312 HydrophobicContact CD1-CB 4.22Å; L254-L312 HydrophobicContact CD1-CD2 4.06Å; L268-L312 HydrophobicContact CB-CD2 3.94Å; L268-L312 HydrophobicContact CD1-CD2 3.82Å; Y269-L312 VanDerWaalsContact CD2-O 3.27Å; Y269-L312 WeakPolarHBondContact CD2-O 3.48Å; K309-L312 HydrophobicContact CB-CB 4.38Å; K309-L312 WeakPolarHBondContact O-CB 3.29Å; K309-L312 PolarHBondContact O-N 2.63Å; C310-L312 PolarHBondContact O-N 3.48Å; C310-L312 VanDerWaalsContact O-N 3.13Å
313A95.9Very high96.7Very high19 Ų1925 Ų2516%0.15715%0.147CC..SBendtrans-94.9153.3175.500000111.5W306 K309 C310W306-A313 WeakPolarHBondContact O-CB 3.09Å; K309-A313 HydrophobicContact CB-CB 4.32Å; C310-A313 WeakPolarHBondContact O-CB 3.35Å; C310-A313 PolarHBondContact O-N 2.88Å
314G95.9Very high96.7Very high17 Ų1725 Ų2518%0.17515%0.147CC..  trans-73-174.7172.900000114.6D50 Y269 P305D50-G314 WeakPolarHBondContact OD1-CA 3.38Å; D50-G314 WeakPolarHBondContact OD2-CA 3.11Å; Y269-G314 VanDerWaalsContact CE2-N 3.3Å; Y269-G314 WeakPolarHBondContact OH-CA 3.47Å; P305-G314 VanDerWaalsContact CB-C 3.41Å; P305-G314 WeakPolarHBondContact CB-O 3.29Å
315S97Very high96.6Very high21 Ų2127.4 Ų27.415%0.14717%0.167CC..  trans-110.1129.8-173.4-176.70000112.2G47 G49 D50 G317G47-S315 CarbonylContact C-O 3.58Å; G47-S315 VanDerWaalsContact CA-O 3.31Å; G47-S315 WeakPolarHBondContact CA-O 3.43Å; G49-S315 WeakPolarHBondContact CA-O 3.18Å; G49-S315 PolarHBondContact N-O 3.3Å; D50-S315 WeakPolarHBondContact OD1-CB 3.29Å; D50-S315 PolarHBondContact OD1-N 2.85Å; D50-S315 PolarHBondContact OD2-N 2.78Å; S315-G317 PolarHBondContact O-N 3.32Å; S315-G317 PolarHBondContact OG-N 2.89Å
316V97.5Very high96.5Very high27 Ų2736.4 Ų36.416%0.16420%0.2CC..  trans-74.3-5.6169.9-60.60000113P305 A318 F319 T320 A332P305-V316 HydrophobicContact CG-CG1 3.6Å; V316-A318 PolarHBondContact O-N 2.63Å; V316-F319 WeakPolarHBondContact O-CD2 3.43Å; V316-F319 PolarHBondContact O-N 3.33Å; V316-T320 HydrophobicContact CG2-CG2 4.27Å; V316-A332 HydrophobicContact CG1-CB 3.88Å
317G97.1Very high96.5Very high9 Ų939.9 Ų39.99%0.09321%0.213CC..THydrogen-bonded Turntrans60.5-129.9-173.800000111.2S315 F319S315-G317 PolarHBondContact O-N 3.32Å; S315-G317 PolarHBondContact OG-N 2.89Å; G317-F319 VanDerWaalsContact C-N 3.28Å; G317-F319 PolarHBondContact O-N 2.94Å
318A96.7Very high96.5Very high26 Ų2639.6 Ų39.622%0.21521%0.213CC..THydrogen-bonded Turntrans-75.5-12.4179.300000114.4W55 V316 T320 I462W55-A318 HydrophobicContact CZ3-CB 4.22Å; V316-A318 PolarHBondContact O-N 2.63Å; A318-T320 VanDerWaalsContact C-N 3.25Å; A318-T320 PolarHBondContact O-N 2.88Å; A318-I462 HydrophobicContact CB-CD1 3.62Å
319F98.1Very high96.6Very high10 Ų1037.8 Ų37.84%0.04421%0.207CC..  trans-84.662.2-173.2-57.1-61.6000112.4W48 V316 G317 G321 E338 R342 I462W48-F319 HydrophobicContact CB-CD2 4.11Å; W48-F319 HydrophobicContact CB-CE2 4.24Å; W48-F319 HydrophobicContact CD2-CD2 4.12Å; W48-F319 AromaticContact CD2-CE2 3.48Å; W48-F319 HydrophobicContact CD2-CE2 3.48Å; W48-F319 VanDerWaalsContact CD2-CE2 3.48Å; W48-F319 AromaticContact CE2-CE2 3.73Å; W48-F319 HydrophobicContact CE3-CD2 4.27Å; W48-F319 AromaticContact CE3-CE2 3.81Å; W48-F319 HydrophobicContact CE3-CE2 3.81Å; W48-F319 HydrophobicContact CG-CD2 4.05Å; W48-F319 AromaticContact CG-CE2 3.67Å; W48-F319 HydrophobicContact CG-CE2 3.67Å; W48-F319 HydrophobicContact CZ2-CE2 4.28Å; W48-F319 HydrophobicContact CZ3-CE2 4.34Å; W48-F319 AromaticContact NE1-CE2 3.99Å; V316-F319 WeakPolarHBondContact O-CD2 3.43Å; V316-F319 PolarHBondContact O-N 3.33Å; G317-F319 VanDerWaalsContact C-N 3.28Å; G317-F319 PolarHBondContact O-N 2.94Å; F319-G321 PolarHBondContact O-N 3.22Å; F319-E338 HydrophobicContact CB-CB 3.7Å; F319-E338 HydrophobicContact CD1-CB 3.8Å; F319-E338 HydrophobicContact CD1-CG 4.3Å; F319-E338 HydrophobicContact CG-CB 3.94Å; F319-R342 HydrophobicContact CD2-CG 4.43Å; F319-R342 HydrophobicContact CE2-CG 4.17Å; F319-I462 HydrophobicContact CD1-CB 4.37Å; F319-I462 WeakPolarHBondContact CD1-O 3.31Å; F319-I462 HydrophobicContact CE1-CB 3.96Å; F319-I462 HydrophobicContact CE1-CG2 4.44Å
320T97.5Very high96.7Very high57 Ų5737.6 Ų37.635%0.3521%0.208SC..  trans-86.20.7-16653.20000115.2V316 A318 V322 P331V316-T320 HydrophobicContact CG2-CG2 4.27Å; A318-T320 VanDerWaalsContact C-N 3.25Å; A318-T320 PolarHBondContact O-N 2.88Å; T320-V322 VanDerWaalsContact C-N 3.28Å; T320-V322 PolarHBondContact O-N 2.59Å; T320-V322 WeakPolarHBondContact OG1-CG2 3.31Å; T320-P331 WeakPolarHBondContact O-CG 3.24Å
321G97.8Very high96.9Very high0 Ų036.8 Ų36.80%020%0.202CC..  trans48.147175.300000113.4F319 W323 Q324 A325 A463F319-G321 PolarHBondContact O-N 3.22Å; G321-W323 PolarHBondContact O-N 2.88Å; G321-W323 VanDerWaalsContact O-N 3.13Å; G321-Q324 WeakPolarHBondContact O-CA 3.42Å; G321-Q324 WeakPolarHBondContact O-CB 3.39Å; G321-Q324 PolarHBondContact O-N 3.29Å; G321-A325 PolarHBondContact O-N 2.88Å; G321-A463 CarbonylContact C-O 3.56Å; G321-A463 VanDerWaalsContact CA-O 3.25Å; G321-A463 WeakPolarHBondContact CA-O 3.35Å; G321-A463 PolarHBondContact N-O 2.87Å; G321-A463 VanDerWaalsContact N-O 3.14Å
322V98.2Very high97.1Very high31 Ų3131.1 Ų31.119%0.18818%0.175CC..Hα-helixtrans-56.7-36.5-165.5170.30000112.1T320 Q324 A325 R326 A463 A465T320-V322 VanDerWaalsContact C-N 3.28Å; T320-V322 PolarHBondContact O-N 2.59Å; T320-V322 WeakPolarHBondContact OG1-CG2 3.31Å; V322-Q324 VanDerWaalsContact C-N 3.29Å; V322-Q324 PolarHBondContact O-N 3.24Å; V322-A325 PolarHBondContact O-N 3.05Å; V322-R326 HydrophobicContact CG1-CG 4.35Å; V322-R326 WeakPolarHBondContact O-CB 3.47Å; V322-R326 VanDerWaalsContact O-CG 3.3Å; V322-R326 WeakPolarHBondContact O-CG 3.38Å; V322-R326 PolarHBondContact O-N 2.84Å; V322-R326 VanDerWaalsContact O-N 3.09Å; V322-A463 HydrophobicContact CG2-CB 4.05Å; V322-A463 PolarHBondContact N-O 2.75Å; V322-A465 HydrophobicContact CB-CB 3.79Å; V322-A465 HydrophobicContact CG1-CB 3.97Å; V322-A465 HydrophobicContact CG2-CB 4.43Å
323W98.2Very high97.3Very high19 Ų1931.1 Ų31.17%0.07218%0.175CC..Hα-helixtrans-59.1-42.3176.5-174.299.5000112G321 R327 W337 T434 L448 L454 F456 E464G321-W323 PolarHBondContact O-N 2.88Å; G321-W323 VanDerWaalsContact O-N 3.13Å; W323-R327 VanDerWaalsContact CZ2-NE 3.34Å; W323-R327 PolarHBondContact O-NH1 3.17Å; W323-W337 HydrophobicContact CB-CH2 4.39Å; W323-W337 HydrophobicContact CD2-CH2 4.15Å; W323-W337 AromaticContact CE3-CH2 3.47Å; W323-W337 HydrophobicContact CE3-CH2 3.47Å; W323-W337 VanDerWaalsContact CE3-CH2 3.47Å; W323-W337 AromaticContact CE3-CZ2 3.71Å; W323-W337 HydrophobicContact CE3-CZ2 3.71Å; W323-W337 HydrophobicContact CZ3-CH2 4.11Å; W323-W337 HydrophobicContact CZ3-CZ2 4.04Å; W323-T434 HydrophobicContact CH2-CG2 4.43Å; W323-T434 HydrophobicContact CZ3-CG2 4.06Å; W323-L448 HydrophobicContact CH2-CD1 3.8Å; W323-L448 HydrophobicContact CZ3-CD1 4.47Å; W323-L454 HydrophobicContact CD2-CD1 4.2Å; W323-L454 HydrophobicContact CE3-CD1 4.45Å; W323-L454 HydrophobicContact CH2-CD1 3.66Å; W323-L454 HydrophobicContact CZ2-CD1 3.33Å; W323-L454 HydrophobicContact CZ3-CD1 4.21Å; W323-F456 HydrophobicContact CB-CE1 4.11Å; W323-F456 HydrophobicContact CB-CZ 4.01Å; W323-F456 HydrophobicContact CG-CE1 4.37Å; W323-F456 AromaticContact CG-CZ 3.98Å; W323-F456 HydrophobicContact CG-CZ 3.98Å; W323-E464 WeakPolarHBondContact CB-O 3.43Å; W323-E464 PolarHBondContact N-O 3.13Å
324Q97.8Very high97.4Very high0 Ų033.1 Ų33.10%018%0.181CC..Hα-helixtrans-74.2-47.2177.6-175.655.959.300111.5G321 V322 R326 R327 G328 W337 G435 G445G321-Q324 WeakPolarHBondContact O-CA 3.42Å; G321-Q324 WeakPolarHBondContact O-CB 3.39Å; G321-Q324 PolarHBondContact O-N 3.29Å; V322-Q324 VanDerWaalsContact C-N 3.29Å; V322-Q324 PolarHBondContact O-N 3.24Å; Q324-R326 PolarHBondContact O-N 3.01Å; Q324-R327 CarbonylContact O-C 3.6Å; Q324-R327 WeakPolarHBondContact O-CA 3.29Å; Q324-R327 WeakPolarHBondContact O-CB 3.35Å; Q324-R327 PolarHBondContact O-N 3.31Å; Q324-G328 PolarHBondContact NE2-O 3Å; Q324-G328 PolarHBondContact O-N 3.34Å; Q324-W337 HydrophobicContact CB-CD2 4.08Å; Q324-W337 VanDerWaalsContact CB-CE2 3.47Å; Q324-W337 HydrophobicContact CB-CH2 4.29Å; Q324-W337 HydrophobicContact CB-CZ2 3.6Å; Q324-W337 HydrophobicContact CG-CZ2 4.19Å; Q324-G435 VanDerWaalsContact CD-C 3.45Å; Q324-G435 VanDerWaalsContact OE1-C 3.27Å; Q324-G435 PolarHBondContact OE1-O 3.01Å; Q324-G445 VanDerWaalsContact NE2-CA 3.33Å
325A96.1Very high97.5Very high51 Ų5132.5 Ų32.542%0.42117%0.174SC..Hα-helixtrans-56.2-37.6-177.700000112G321 V322 R327 G328G321-A325 PolarHBondContact O-N 2.88Å; V322-A325 PolarHBondContact O-N 3.05Å; A325-R327 PolarHBondContact O-N 3.39Å; A325-G328 PolarHBondContact O-N 3.45Å
326R96.9Very high97.6Very high191 Ų19132 Ų3272%0.72117%0.17SC*.THydrogen-bonded Turntrans-65.6-14.6174.5-72.9176.5179.8178.12.9114.6V322 Q324V322-R326 HydrophobicContact CG1-CG 4.35Å; V322-R326 WeakPolarHBondContact O-CB 3.47Å; V322-R326 VanDerWaalsContact O-CG 3.3Å; V322-R326 WeakPolarHBondContact O-CG 3.38Å; V322-R326 PolarHBondContact O-N 2.84Å; V322-R326 VanDerWaalsContact O-N 3.09Å; Q324-R326 PolarHBondContact O-N 3.01Å
327R96.6Very high97.7Very high112 Ų11230.7 Ų30.742%0.42316%0.162SC..THydrogen-bonded Turntrans-107.14178.5-67.8171.8173.374.70.6112.7W323 Q324 A325 P446W323-R327 VanDerWaalsContact CZ2-NE 3.34Å; W323-R327 PolarHBondContact O-NH1 3.17Å; Q324-R327 CarbonylContact O-C 3.6Å; Q324-R327 WeakPolarHBondContact O-CA 3.29Å; Q324-R327 WeakPolarHBondContact O-CB 3.35Å; Q324-R327 PolarHBondContact O-N 3.31Å; A325-R327 PolarHBondContact O-N 3.39Å; R327-P446 WeakPolarHBondContact O-CD 3.37Å
328G96.6Very high97.8Very high20 Ų2030.2 Ų30.221%0.20616%0.158CC..SBendtrans96.1163.8-178.800000113.6Q324 A325 G445Q324-G328 PolarHBondContact NE2-O 3Å; Q324-G328 PolarHBondContact O-N 3.34Å; A325-G328 PolarHBondContact O-N 3.45Å; G328-G445 VanDerWaalsContact C-CA 3.48Å; G328-G445 WeakPolarHBondContact O-CA 3.4Å; G328-G445 PolarHBondContact O-N 3.28Å
329G97.3Very high97.8Very high9 Ų929.1 Ų29.19%0.09315%0.148CC..SBendtrans71.4-173.4-176.100000114A437 S443G329-A437 CarbonylContact C-O 3.29Å; G329-A437 WeakPolarHBondContact CA-O 3.39Å; G329-S443 PolarHBondContact N-OG 3.33Å; G329-S443 VanDerWaalsContact N-OG 3.13Å
330S97.9Very high97.9Very high11 Ų1128.6 Ų28.68%0.07715%0.146CC..BIsolated β-bridgetrans-111.3142.9-177.9176.90000111.7A307 A332 T335 G436 A437A307-S330 WeakPolarHBondContact CB-OG 3.43Å; S330-A332 VanDerWaalsContact C-N 3.27Å; S330-A332 WeakPolarHBondContact OG-CB 3.14Å; S330-A332 PolarHBondContact OG-N 3.01Å; S330-A332 VanDerWaalsContact OG-N 3.14Å; S330-T335 WeakPolarHBondContact O-CG2 3.41Å; S330-G436 CarbonylContact O-C 3.6Å; S330-G436 WeakPolarHBondContact O-CA 3.18Å; S330-A437 PolarHBondContact N-O 2.96Å; S330-A437 PolarHBondContact O-N 3.42Å
331P97.9Very high97.9Very high12 Ų1226 Ų268%0.07813%0.13CC..SBendtrans-8814.8171.238.9-37.6000113.2T320 T335 W337 G339 G340T320-P331 WeakPolarHBondContact O-CG 3.24Å; P331-T335 PolarHBondContact O-OG1 2.75Å; P331-W337 HydrophobicContact CB-CB 3.63Å; P331-W337 HydrophobicContact CB-CG 3.83Å; P331-W337 WeakPolarHBondContact O-CB 3.22Å; P331-G339 CarbonylContact O-C 3.53Å; P331-G340 PolarHBondContact O-N 2.88Å; P331-G340 VanDerWaalsContact O-N 3.1Å
332A98.1Very high98Very high1 Ų126.5 Ų26.51%0.00813%0.132CC..SBendtrans-91.8-144.6-175.900000112P305 A307 V316 S330 T335 G340P305-A332 HydrophobicContact CG-CB 4.11Å; P305-A332 WeakPolarHBondContact O-CB 3.24Å; A307-A332 HydrophobicContact CB-CB 4.1Å; V316-A332 HydrophobicContact CG1-CB 3.88Å; S330-A332 VanDerWaalsContact C-N 3.27Å; S330-A332 WeakPolarHBondContact OG-CB 3.14Å; S330-A332 PolarHBondContact OG-N 3.01Å; S330-A332 VanDerWaalsContact OG-N 3.14Å; A332-T335 WeakPolarHBondContact O-CB 3.34Å; A332-T335 WeakPolarHBondContact O-CG2 3.19Å; A332-T335 PolarHBondContact O-N 3.38Å; A332-T335 VanDerWaalsContact O-N 3.16Å; A332-T335 PolarHBondContact O-OG1 2.93Å; A332-G340 WeakPolarHBondContact O-CA 3.47Å
333K98.4Very high98Very high10 Ų1025 Ų254%0.04312%0.123CC..THydrogen-bonded Turntrans-40.6143.4178.4-170.9179.9179.5174.60112.1D45 S82 H251 P305 W306 T335 A437D45-K333 WeakPolarHBondContact OD1-CD 3.12Å; D45-K333 WeakPolarHBondContact OD1-CE 3.35Å; D45-K333 IonicContact OD1-NZ 3.28Å; D45-K333 PolarHBondContact OD1-NZ 3.48Å; D45-K333 IonicContact OD2-NZ 3.77Å; D45-K333 PolarHBondContact OD2-NZ 3.09Å; S82-K333 WeakPolarHBondContact O-CG 3.34Å; S82-K333 WeakPolarHBondContact OG-CA 3.27Å; H251-K333 PolarHBondContact CD2-NZ 3.4Å; H251-K333 PolarHBondContact NE2-NZ 3.29Å; P305-K333 WeakPolarHBondContact O-CB 3.08Å; P305-K333 PolarHBondContact O-N 3.2Å; P305-K333 VanDerWaalsContact O-N 3.13Å; W306-K333 HydrophobicContact CB-CD 3.75Å; W306-K333 HydrophobicContact CD2-CD 4.36Å; W306-K333 HydrophobicContact CG-CD 3.86Å; K333-T335 VanDerWaalsContact C-N 3.29Å; K333-A437 WeakPolarHBondContact O-CB 3.35Å
334Q98.3Very high98Very high62 Ų6224.1 Ų24.129%0.2912%0.119SC..THydrogen-bonded Turntrans75.9-3.5-173.4-53.3-179.9-33.200116.4S82 T83 S411 A413 A437S82-Q334 WeakPolarHBondContact O-CA 3.35Å; S82-Q334 PolarHBondContact O-N 3.03Å; S82-Q334 PolarHBondContact OG-N 3.39Å; T83-Q334 HydrophobicContact CG2-CG 4.14Å; Q334-S411 WeakPolarHBondContact CA-O 3.44Å; Q334-S411 WeakPolarHBondContact CB-O 3.39Å; Q334-S411 CarbonylContact O-C 3.56Å; Q334-S411 VanDerWaalsContact O-C 3.24Å; Q334-A413 HydrophobicContact CB-CB 4.41Å; Q334-A413 VanDerWaalsContact O-CB 3.23Å; Q334-A413 WeakPolarHBondContact O-CB 3.48Å; Q334-A413 PolarHBondContact O-N 3.25Å; Q334-A413 VanDerWaalsContact O-N 3.07Å; Q334-A437 HydrophobicContact CB-CB 4.11Å
335T98.6Very high98Very high3 Ų324.1 Ų24.12%0.01812%0.119CC..SBendtrans-110.8165-179.879.50000113.4S82 S330 P331 A332 K333 W337 A413 A437S82-T335 WeakPolarHBondContact CB-O 3.47Å; S82-T335 PolarHBondContact OG-N 2.86Å; S82-T335 PolarHBondContact OG-O 2.77Å; S330-T335 WeakPolarHBondContact O-CG2 3.41Å; P331-T335 PolarHBondContact O-OG1 2.75Å; A332-T335 WeakPolarHBondContact O-CB 3.34Å; A332-T335 WeakPolarHBondContact O-CG2 3.19Å; A332-T335 PolarHBondContact O-N 3.38Å; A332-T335 VanDerWaalsContact O-N 3.16Å; A332-T335 PolarHBondContact O-OG1 2.93Å; K333-T335 VanDerWaalsContact C-N 3.29Å; T335-W337 PolarHBondContact OG1-N 3.12Å; T335-A413 HydrophobicContact CG2-CB 3.67Å; T335-A437 HydrophobicContact CG2-CB 3.74Å
336T98.5Very high98.2Very high10 Ų1021.7 Ų21.76%0.06110%0.099CC..SBendtrans-95.76.5172.7590000113H341 H408 T422 K429 F431T336-H341 PolarHBondContact O-CD2 2.92Å; T336-H341 PolarHBondContact O-NE2 3.42Å; T336-H408 HydrophobicContact CG2-CB 4.13Å; T336-H408 WeakPolarHBondContact CG2-O 3.27Å; T336-T422 WeakPolarHBondContact CB-OG1 3.31Å; T336-T422 PolarHBondContact OG1-OG1 3Å; T336-K429 WeakPolarHBondContact O-CE 3.38Å; T336-K429 PolarHBondContact O-NZ 2.76Å; T336-F431 WeakPolarHBondContact OG1-CE1 3.46Å
337W98.8Very high98.3Very high0 Ų012.6 Ų12.60%07%0.065CC..SBendtrans-69.1158.7170.9-60104.5000110.8W323 Q324 P331 T335 G339 G340 H341 K429 F431 T434 G435 F456 E464W323-W337 HydrophobicContact CB-CH2 4.39Å; W323-W337 HydrophobicContact CD2-CH2 4.15Å; W323-W337 AromaticContact CE3-CH2 3.47Å; W323-W337 HydrophobicContact CE3-CH2 3.47Å; W323-W337 VanDerWaalsContact CE3-CH2 3.47Å; W323-W337 AromaticContact CE3-CZ2 3.71Å; W323-W337 HydrophobicContact CE3-CZ2 3.71Å; W323-W337 HydrophobicContact CZ3-CH2 4.11Å; W323-W337 HydrophobicContact CZ3-CZ2 4.04Å; Q324-W337 HydrophobicContact CB-CD2 4.08Å; Q324-W337 VanDerWaalsContact CB-CE2 3.47Å; Q324-W337 HydrophobicContact CB-CH2 4.29Å; Q324-W337 HydrophobicContact CB-CZ2 3.6Å; Q324-W337 HydrophobicContact CG-CZ2 4.19Å; P331-W337 HydrophobicContact CB-CB 3.63Å; P331-W337 HydrophobicContact CB-CG 3.83Å; P331-W337 WeakPolarHBondContact O-CB 3.22Å; T335-W337 PolarHBondContact OG1-N 3.12Å; W337-G339 PolarHBondContact O-N 2.75Å; W337-G340 PolarHBondContact O-N 3.4Å; W337-H341 PolarHBondContact O-CD2 2.78Å; W337-H341 PolarHBondContact O-NE2 3.26Å; W337-K429 VanDerWaalsContact C-NZ 3.31Å; W337-F431 HydrophobicContact CD2-CE1 4.06Å; W337-F431 HydrophobicContact CD2-CZ 4.01Å; W337-F431 HydrophobicContact CE3-CE1 4.04Å; W337-F431 HydrophobicContact CE3-CE2 4.11Å; W337-F431 AromaticContact CE3-CZ 3.54Å; W337-F431 HydrophobicContact CE3-CZ 3.54Å; W337-F431 HydrophobicContact CH2-CZ 4.39Å; W337-F431 HydrophobicContact CZ3-CD2 4.48Å; W337-F431 HydrophobicContact CZ3-CE1 4.28Å; W337-F431 AromaticContact CZ3-CE2 3.89Å; W337-F431 HydrophobicContact CZ3-CE2 3.89Å; W337-F431 AromaticContact CZ3-CZ 3.75Å; W337-F431 HydrophobicContact CZ3-CZ 3.75Å; W337-T434 HydrophobicContact CH2-CG2 3.88Å; W337-T434 HydrophobicContact CZ2-CG2 3.63Å; W337-G435 PolarHBondContact NE1-O 2.72Å; W337-F456 HydrophobicContact CH2-CE2 4.22Å; W337-F456 HydrophobicContact CH2-CZ 4.19Å; W337-F456 AromaticContact CZ3-CE2 3.9Å; W337-F456 HydrophobicContact CZ3-CE2 3.9Å; W337-F456 AromaticContact CZ3-CZ 3.94Å; W337-F456 HydrophobicContact CZ3-CZ 3.94Å; W337-E464 HydrophobicContact CE3-CB 3.98Å; W337-E464 HydrophobicContact CE3-CG 4.37Å; W337-E464 HydrophobicContact CZ3-CB 3.97Å
338E98.8Very high98.4Very high0 Ų07.4 Ų7.40%05%0.046CC..Hα-helixtrans-56.9-39.9-173.3-71.7-64.291.100112.1H78 F319 G340 H341 R342 K429 L458 E464H78-E338 IonicContact CE1-OE1 3.65Å; H78-E338 IonicContact CE1-OE2 2.61Å; F319-E338 HydrophobicContact CB-CB 3.7Å; F319-E338 HydrophobicContact CD1-CB 3.8Å; F319-E338 HydrophobicContact CD1-CG 4.3Å; F319-E338 HydrophobicContact CG-CB 3.94Å; E338-G340 PolarHBondContact O-N 3.19Å; E338-G340 VanDerWaalsContact O-N 3.12Å; E338-H341 PolarHBondContact O-N 3.32Å; E338-H341 IonicContact OE1-CE1 2.64Å; E338-H341 PolarHBondContact OE1-CE1 2.87Å; E338-H341 IonicContact OE1-NE2 3.27Å; E338-R342 WeakPolarHBondContact O-CB 3.35Å; E338-R342 PolarHBondContact O-N 3.12Å; E338-R342 IonicContact OE2-CZ 3.84Å; E338-R342 IonicContact OE2-NE 3.63Å; E338-R342 PolarHBondContact OE2-NE 3.38Å; E338-R342 VanDerWaalsContact OE2-NE 3.12Å; E338-R342 IonicContact OE2-NH1 2.6Å; E338-R342 PolarHBondContact OE2-NH1 3.35Å; E338-R342 IonicContact OE2-NH2 3.13Å; E338-R342 PolarHBondContact OE2-NH2 2.98Å; E338-K429 HydrophobicContact CG-CD 4.46Å; E338-K429 WeakPolarHBondContact OE1-CD 3.28Å; E338-K429 WeakPolarHBondContact OE1-CE 3.36Å; E338-K429 IonicContact OE1-NZ 2.62Å; E338-K429 PolarHBondContact OE1-NZ 3.36Å; E338-L458 VanDerWaalsContact CD-CD1 3.44Å; E338-L458 HydrophobicContact CG-CD1 3.83Å; E338-L458 WeakPolarHBondContact OE2-CD1 3.18Å; E338-E464 WeakPolarHBondContact CB-OE2 3.21Å; E338-E464 VanDerWaalsContact CG-CD 3.48Å; E338-E464 HydrophobicContact CG-CG 4.12Å; E338-E464 WeakPolarHBondContact CG-OE2 3.13Å; E338-E464 PolarHBondContact N-OE2 3.43Å
339G98.5Very high98.5Very high2 Ų27.3 Ų7.32%0.0214%0.039CC..Hα-helixtrans-63.5-15.5177.200000114.7G304 P305 P331 W337G304-G339 WeakPolarHBondContact CA-O 3.33Å; P305-G339 WeakPolarHBondContact CD-O 3.4Å; P331-G339 CarbonylContact O-C 3.53Å; W337-G339 PolarHBondContact O-N 2.75Å
340G98.4Very high98.5Very high0 Ų08 Ų80%04%0.042CC..Hα-helixtrans-88.8-26.1-179.100000114.6S82 G304 P331 A332 W337 E338S82-G340 WeakPolarHBondContact CB-O 3.18Å; S82-G340 WeakPolarHBondContact OG-CA 3.23Å; S82-G340 PolarHBondContact OG-O 2.73Å; G304-G340 PolarHBondContact N-O 3.39Å; P331-G340 PolarHBondContact O-N 2.88Å; P331-G340 VanDerWaalsContact O-N 3.1Å; A332-G340 WeakPolarHBondContact O-CA 3.47Å; W337-G340 PolarHBondContact O-N 3.4Å; E338-G340 PolarHBondContact O-N 3.19Å; E338-G340 VanDerWaalsContact O-N 3.12Å
341H98.5Very high98.3Very high2 Ų211.5 Ų11.51%0.0098%0.079CC..Hα-helixtrans-137.3-15-17461.978000114.6H78 A79 T336 W337 E338 V343 H408 K429H78-H341 CarbonylContact C-O 3.53Å; H78-H341 WeakPolarHBondContact CA-O 3.4Å; H78-H341 AromaticContact CE1-CE1 3.59Å; H78-H341 AromaticContact CE1-ND1 3.66Å; H78-H341 AromaticContact CG-ND1 3.82Å; H78-H341 AromaticContact ND1-CE1 3.16Å; H78-H341 PolarHBondContact ND1-CE1 2.99Å; H78-H341 AromaticContact ND1-ND1 2.8Å; H78-H341 PolarHBondContact ND1-ND1 3.48Å; A79-H341 HydrophobicContact CB-CB 4.3Å; A79-H341 WeakPolarHBondContact CB-O 3.11Å; A79-H341 PolarHBondContact N-O 3.37Å; T336-H341 PolarHBondContact O-CD2 2.92Å; T336-H341 PolarHBondContact O-NE2 3.42Å; W337-H341 PolarHBondContact O-CD2 2.78Å; W337-H341 PolarHBondContact O-NE2 3.26Å; E338-H341 PolarHBondContact O-N 3.32Å; E338-H341 IonicContact OE1-CE1 2.64Å; E338-H341 PolarHBondContact OE1-CE1 2.87Å; E338-H341 IonicContact OE1-NE2 3.27Å; H341-V343 PolarHBondContact O-N 3.25Å; H341-H408 AromaticContact CD2-CG 4Å; H341-H408 AromaticContact CD2-ND1 3.89Å; H341-H408 AromaticContact CE1-CD2 3.76Å; H341-H408 AromaticContact CE1-CE1 3.1Å; H341-H408 PolarHBondContact CE1-CE1 3.25Å; H341-H408 AromaticContact CE1-CG 3.66Å; H341-H408 AromaticContact CE1-ND1 3.26Å; H341-H408 PolarHBondContact CE1-ND1 2.84Å; H341-H408 VanDerWaalsContact CE1-ND1 3.26Å; H341-H408 AromaticContact CE1-NE2 3.42Å; H341-H408 PolarHBondContact CE1-NE2 3.45Å; H341-H408 AromaticContact CG-ND1 3.71Å; H341-H408 AromaticContact ND1-CE1 3.34Å; H341-H408 PolarHBondContact ND1-CE1 3.17Å; H341-H408 VanDerWaalsContact ND1-CE1 3.34Å; H341-H408 AromaticContact ND1-ND1 3.31Å; H341-H408 PolarHBondContact ND1-ND1 3.41Å; H341-H408 AromaticContact NE2-CD2 3.79Å; H341-H408 AromaticContact NE2-CE1 3.81Å; H341-H408 AromaticContact NE2-CG 3.57Å; H341-H408 AromaticContact NE2-ND1 3.59Å; H341-H408 AromaticContact NE2-NE2 3.93Å; H341-K429 PolarHBondContact NE2-NZ 3.31Å
342R98.7Very high98.3Very high10 Ų1018 Ų184%0.03810%0.102CC..BIsolated β-bridgetrans-75.2120.8168.6-171.3170.9-84.6172.7-4.6108.8W48 D76 F77 H78 F319 E338W48-R342 HydrophobicContact CG-CG 4.44Å; D76-R342 IonicContact OD1-CZ 3.39Å; D76-R342 IonicContact OD1-NE 2.91Å; D76-R342 IonicContact OD1-NH2 3.9Å; D76-R342 PolarHBondContact OD1-NH2 3.3Å; D76-R342 IonicContact OD2-NH2 3.19Å; D76-R342 PolarHBondContact OD2-NH2 2.99Å; F77-R342 WeakPolarHBondContact O-CA 3.46Å; H78-R342 PolarHBondContact CE1-NE 3.32Å; H78-R342 VanDerWaalsContact CE1-NE 3.32Å; H78-R342 PolarHBondContact NE2-NE 2.81Å; H78-R342 PolarHBondContact NE2-NH2 3.34Å; F319-R342 HydrophobicContact CD2-CG 4.43Å; F319-R342 HydrophobicContact CE2-CG 4.17Å; E338-R342 WeakPolarHBondContact O-CB 3.35Å; E338-R342 PolarHBondContact O-N 3.12Å; E338-R342 IonicContact OE2-CZ 3.84Å; E338-R342 IonicContact OE2-NE 3.63Å; E338-R342 PolarHBondContact OE2-NE 3.38Å; E338-R342 VanDerWaalsContact OE2-NE 3.12Å; E338-R342 IonicContact OE2-NH1 2.6Å; E338-R342 PolarHBondContact OE2-NH1 3.35Å; E338-R342 IonicContact OE2-NH2 3.13Å; E338-R342 PolarHBondContact OE2-NH2 2.98Å
343V98.8Very high98.3Very high0 Ų018.2 Ų18.20%010%0.103CC..  trans-126.8157-169.2-68.50000110.1F77 A79 T300 H341F77-V343 HydrophobicContact CD1-CG2 3.82Å; F77-V343 HydrophobicContact CE1-CG2 4.35Å; F77-V343 PolarHBondContact O-N 3.07Å; A79-V343 HydrophobicContact CB-CG1 4.18Å; A79-V343 HydrophobicContact CB-CG2 4.48Å; T300-V343 WeakPolarHBondContact OG1-CG2 3.43Å; H341-V343 PolarHBondContact O-N 3.25Å
344P98.6Very high98.3Very high0 Ų019.8 Ų19.80%011%0.114CC..  trans-66.1145.1174.528.7-32.7000109.6M46 L51 F299 T300 G301M46-P344 HydrophobicContact CE-CG 3.93Å; M46-P344 HydrophobicContact CG-CG 3.98Å; M46-P344 HydrophobicContact SD-CG 3.71Å; L51-P344 HydrophobicContact CB-CB 3.83Å; L51-P344 HydrophobicContact CD2-CB 3.86Å; L51-P344 HydrophobicContact CG-CB 4.48Å; F299-P344 HydrophobicContact CE1-CG 4.33Å; T300-P344 WeakPolarHBondContact CA-O 3.46Å; T300-P344 PolarHBondContact OG1-O 3.09Å; G301-P344 PolarHBondContact N-O 3.44Å
345A98.8Very high98.2Very high0 Ų021.2 Ų21.20%013%0.127CC..EExtended strand (participates in β ladder)trans-148.3134.617400000113F74 F77 F299F74-A345 HydrophobicContact CB-CB 4.19Å; F74-A345 HydrophobicContact CD2-CB 4.11Å; F74-A345 PolarHBondContact N-O 2.87Å; F77-A345 HydrophobicContact CB-CB 3.64Å; F77-A345 HydrophobicContact CD1-CB 3.52Å; F77-A345 HydrophobicContact CD2-CB 3.76Å; F77-A345 HydrophobicContact CE1-CB 4.06Å; F77-A345 HydrophobicContact CE2-CB 4.32Å; F77-A345 HydrophobicContact CG-CB 3.34Å; F77-A345 HydrophobicContact CZ-CB 4.45Å; F299-A345 CarbonylContact O-C 3.56Å; F299-A345 VanDerWaalsContact O-CA 3.24Å; F299-A345 WeakPolarHBondContact O-CA 3.46Å
346L98.9Very high98.2Very high0 Ų027 Ų270%016%0.158CC..EExtended strand (participates in β ladder)trans-132.6139.1-179.2-56.3176.7000110.9L51 L64 M67 A68 M72 R73 W298 F299L51-L346 HydrophobicContact CD1-CD1 4.41Å; L51-L346 HydrophobicContact CD2-CD1 4.26Å; L51-L346 HydrophobicContact CD2-CD2 3.98Å; L51-L346 HydrophobicContact CD2-CG 4.16Å; L64-L346 HydrophobicContact CB-CD1 4.11Å; L64-L346 HydrophobicContact CD2-CD1 3.99Å; L64-L346 VanDerWaalsContact O-CD1 3.29Å; L64-L346 WeakPolarHBondContact O-CD1 3.33Å; M67-L346 HydrophobicContact CB-CD1 4.3Å; M67-L346 HydrophobicContact CE-CB 4.14Å; M67-L346 HydrophobicContact CG-CD1 4.37Å; M67-L346 HydrophobicContact SD-CB 4.33Å; M67-L346 HydrophobicContact SD-CD1 4.31Å; A68-L346 HydrophobicContact CB-CD1 4.19Å; A68-L346 HydrophobicContact CB-CD2 3.53Å; M72-L346 CarbonylContact O-C 3.36Å; M72-L346 WeakPolarHBondContact O-CA 3.46Å; R73-L346 HydrophobicContact CB-CD2 3.7Å; R73-L346 HydrophobicContact CG-CD2 3.72Å; W298-L346 WeakPolarHBondContact CA-O 3.47Å; F299-L346 HydrophobicContact CB-CB 4.29Å; F299-L346 HydrophobicContact CD1-CD1 4.48Å; F299-L346 PolarHBondContact N-O 3.13Å; F299-L346 PolarHBondContact O-N 2.64Å
347A98.8Very high98.1Very high0 Ų028.9 Ų28.90%017%0.169CC..EExtended strand (participates in β ladder)trans-118.9132.4172.500000110.2G71 M72 F74 F296 L297 V353 L395G71-A347 WeakPolarHBondContact CA-O 3.19Å; M72-A347 HydrophobicContact CB-CB 4.39Å; M72-A347 PolarHBondContact N-O 2.98Å; M72-A347 PolarHBondContact O-N 3.1Å; F74-A347 HydrophobicContact CE2-CB 3.71Å; F74-A347 HydrophobicContact CZ-CB 4.2Å; F296-A347 HydrophobicContact CE2-CB 3.87Å; F296-A347 HydrophobicContact CZ-CB 4.31Å; L297-A347 WeakPolarHBondContact O-CA 3.4Å; A347-V353 HydrophobicContact CB-CG1 4.38Å; A347-L395 HydrophobicContact CB-CD2 3.48Å; A347-L395 VanDerWaalsContact CB-CD2 3.48Å
348Y98.8Very high98.1Very high4 Ų432.2 Ų32.22%0.01619%0.19CC..EExtended strand (participates in β ladder)trans-136.4123.1179.4171.8-99.9000110.6M67 E70 K284 D288 K292 L297 P350M67-Y348 HydrophobicContact CG-CG 4.39Å; E70-Y348 HydrophobicContact CB-CD2 4.05Å; E70-Y348 HydrophobicContact CB-CE2 3.84Å; K284-Y348 HydrophobicContact CG-CE1 4.43Å; K284-Y348 PolarHBondContact NZ-OH 3.3Å; D288-Y348 VanDerWaalsContact CG-OH 3.24Å; D288-Y348 WeakPolarHBondContact OD1-CE1 3.44Å; D288-Y348 PolarHBondContact OD1-OH 3.2Å; D288-Y348 PolarHBondContact OD2-OH 3.2Å; K292-Y348 WeakPolarHBondContact CE-OH 3.34Å; L297-Y348 HydrophobicContact CB-CD1 4.19Å; L297-Y348 HydrophobicContact CD1-CD1 4.42Å; L297-Y348 HydrophobicContact CD2-CD1 4.09Å; L297-Y348 HydrophobicContact CG-CD1 4.46Å; L297-Y348 PolarHBondContact N-O 2.84Å; L297-Y348 PolarHBondContact O-N 2.68Å; Y348-P350 HydrophobicContact CE1-CG 3.82Å; Y348-P350 HydrophobicContact CE2-CG 3.73Å; Y348-P350 WeakPolarHBondContact OH-CG 3.15Å
349W98.5Very high98Very high18 Ų1832.3 Ų32.37%0.06819%0.191CC..  trans-157.499.1170.4-168.8-9000109.3P36 D293 F296 G351 R352 V353 L375 F396P36-W349 HydrophobicContact CB-CH2 3.51Å; P36-W349 HydrophobicContact CB-CZ2 3.66Å; P36-W349 HydrophobicContact CB-CZ3 4.45Å; P36-W349 HydrophobicContact CG-CH2 3.94Å; D293-W349 PolarHBondContact O-NE1 3.13Å; F296-W349 HydrophobicContact CB-CD2 4Å; F296-W349 HydrophobicContact CB-CE3 3.66Å; F296-W349 HydrophobicContact CB-CG 4.45Å; F296-W349 HydrophobicContact CB-CZ3 4.12Å; F296-W349 HydrophobicContact CD2-CB 4.1Å; F296-W349 HydrophobicContact CD2-CE3 4.14Å; F296-W349 HydrophobicContact CG-CE3 4.03Å; W349-G351 PolarHBondContact O-N 2.91Å; W349-R352 HydrophobicContact CB-CB 4.08Å; W349-R352 HydrophobicContact CD2-CB 3.65Å; W349-R352 HydrophobicContact CD2-CG 3.73Å; W349-R352 HydrophobicContact CE3-CB 4.01Å; W349-R352 HydrophobicContact CE3-CG 4.32Å; W349-R352 HydrophobicContact CG-CB 3.66Å; W349-R352 HydrophobicContact CG-CG 3.94Å; W349-R352 HydrophobicContact CZ2-CG 4.05Å; W349-R352 PolarHBondContact O-N 3.13Å; W349-V353 HydrophobicContact CB-CB 4.18Å; W349-V353 HydrophobicContact CB-CG2 3.73Å; W349-V353 PolarHBondContact O-N 3.37Å; W349-L375 HydrophobicContact CZ3-CD1 4.31Å; W349-L375 HydrophobicContact CZ3-CD2 4.38Å; W349-F396 HydrophobicContact CE3-CE1 4.19Å; W349-F396 HydrophobicContact CZ3-CE1 4.12Å; W349-F396 HydrophobicContact CZ3-CZ 4.25Å
350P97.2Very high97.9Very high24 Ų2436.9 Ų36.916%0.15622%0.218CC..THydrogen-bonded Turntrans-52130.1-178.6-31.639.2000112.7K292 Y348 R352K292-P350 HydrophobicContact CD-CG 4.34Å; K292-P350 HydrophobicContact CG-CB 4.2Å; K292-P350 HydrophobicContact CG-CG 3.77Å; Y348-P350 HydrophobicContact CE1-CG 3.82Å; Y348-P350 HydrophobicContact CE2-CG 3.73Å; Y348-P350 WeakPolarHBondContact OH-CG 3.15Å; P350-R352 PolarHBondContact O-N 3Å
351G95.1Very high97.9Very high83 Ų8337 Ų3786%0.85622%0.219SC*.THydrogen-bonded Turntrans75.30.2-179.500000115.6W349W349-G351 PolarHBondContact O-N 2.91Å
352R96.9Very high97.8Very high150 Ų15037.5 Ų37.557%0.56622%0.222SC*.THydrogen-bonded Turntrans-125.5-50.2179.2-62.3-67.6-171.1162.60.4112.8W349 P350 F396W349-R352 HydrophobicContact CB-CB 4.08Å; W349-R352 HydrophobicContact CD2-CB 3.65Å; W349-R352 HydrophobicContact CD2-CG 3.73Å; W349-R352 HydrophobicContact CE3-CB 4.01Å; W349-R352 HydrophobicContact CE3-CG 4.32Å; W349-R352 HydrophobicContact CG-CB 3.66Å; W349-R352 HydrophobicContact CG-CG 3.94Å; W349-R352 HydrophobicContact CZ2-CG 4.05Å; W349-R352 PolarHBondContact O-N 3.13Å; P350-R352 PolarHBondContact O-N 3Å; R352-F396 HydrophobicContact CB-CD1 4.32Å; R352-F396 HydrophobicContact CB-CE1 4.08Å; R352-F396 WeakPolarHBondContact O-CD1 3.18Å
353V98.2Very high97.8Very high5 Ų537 Ų373%0.0322%0.22CC..SBendtrans-86129.1173172.30000108.3M72 F296 A347 W349M72-V353 HydrophobicContact CB-CG1 3.62Å; F296-V353 HydrophobicContact CE2-CG2 4.38Å; A347-V353 HydrophobicContact CB-CG1 4.38Å; W349-V353 HydrophobicContact CB-CB 4.18Å; W349-V353 HydrophobicContact CB-CG2 3.73Å; W349-V353 PolarHBondContact O-N 3.37Å
354P97.8Very high97.8Very high42 Ų4237.1 Ų37.127%0.27322%0.221SC..PPolyproline II helixtrans-55.2138.6174.4-26.934.4000112.6G71 M72 V357 L395G71-P354 CarbonylContact C-O 3.51Å; G71-P354 VanDerWaalsContact O-O 3.08Å; M72-P354 HydrophobicContact CE-CB 4.48Å; M72-P354 HydrophobicContact CE-CG 4.13Å; P354-V357 HydrophobicContact CB-CB 4.25Å; P354-V357 HydrophobicContact CB-CG2 3.54Å; P354-L395 VanDerWaalsContact CD-O 3.23Å; P354-L395 WeakPolarHBondContact CD-O 3.3Å
355V98Very high97.8Very high93 Ų9337.1 Ų37.156%0.56422%0.221SC*.THydrogen-bonded Turntrans-84.1140.6-179.1176.60000110.3S69 G71 V357S69-V355 VanDerWaalsContact O-CG1 3.23Å; S69-V355 WeakPolarHBondContact O-CG1 3.32Å; G71-V355 CarbonylContact O-C 3.52Å; V355-V357 VanDerWaalsContact C-N 3.32Å; V355-V357 PolarHBondContact O-N 3.39Å
356N97.3Very high97.8Very high123 Ų12337.5 Ų37.566%0.65822%0.223SC*.THydrogen-bonded Turntrans56.142.3176.3-166.637.3000113.3S69 G71S69-N356 WeakPolarHBondContact O-CA 3.27Å; S69-N356 WeakPolarHBondContact O-CB 3.38Å; S69-N356 PolarHBondContact O-N 3.17Å; G71-N356 PolarHBondContact O-N 3.38Å
357V97.6Very high97.8Very high50 Ų5037.5 Ų37.530%0.30322%0.223SC..EExtended strand (participates in β ladder)trans-107.6132.2178.3173.10000110.6G71 M72 R73 P354 V355G71-V357 PolarHBondContact O-N 2.75Å; G71-V357 VanDerWaalsContact O-N 3.17Å; M72-V357 CarbonylContact C-O 3.59Å; M72-V357 VanDerWaalsContact CA-O 3.29Å; M72-V357 WeakPolarHBondContact CA-O 3.47Å; M72-V357 HydrophobicContact CE-CB 4.34Å; M72-V357 HydrophobicContact CE-CG1 3.97Å; M72-V357 HydrophobicContact CG-CB 4.39Å; M72-V357 HydrophobicContact CG-CG1 4.27Å; R73-V357 PolarHBondContact N-O 3.38Å; P354-V357 HydrophobicContact CB-CB 4.25Å; P354-V357 HydrophobicContact CB-CG2 3.54Å; V355-V357 VanDerWaalsContact C-N 3.32Å; V355-V357 PolarHBondContact O-N 3.39Å
358T97.7Very high97.8Very high70 Ų7037.5 Ų37.543%0.42922%0.223SC..EExtended strand (participates in β ladder)trans-99.9120.6165.9-63.40000108.7R73 V75R73-T358 PolarHBondContact NH2-OG1 2.91Å; R73-T358 CarbonylContact O-C 3.58Å; R73-T358 WeakPolarHBondContact O-CA 3.24Å; V75-T358 HydrophobicContact CG1-CG2 3.68Å; V75-T358 HydrophobicContact CG2-CG2 4.24Å
359S97.6Very high97.8Very high3 Ų337.3 Ų37.32%0.02122%0.222CC..EExtended strand (participates in β ladder)trans-100133.7175.8177.90000111R73 V75 A361R73-S359 PolarHBondContact O-N 3.35Å; V75-S359 WeakPolarHBondContact CG2-O 3.5Å; V75-S359 PolarHBondContact N-O 2.61Å; V75-S359 VanDerWaalsContact N-O 3.12Å; S359-A361 WeakPolarHBondContact OG-CB 3.32Å; S359-A361 PolarHBondContact OG-N 3.02Å
360T96.1Very high97.8Very high98 Ų9836.8 Ų36.860%0.60122%0.221SC*.  trans-100.39.6174.551.90000112.1V75 L362V75-T360 HydrophobicContact CG2-CG2 3.88Å; T360-L362 PolarHBondContact O-N 2.8Å
361A97.3Very high97.9Very high2 Ų235.7 Ų35.72%0.01721%0.214CC..  trans-59.1131.4175.300000110.2D76 S359 L363 V394 Q400D76-A361 VanDerWaalsContact O-O 3.09Å; S359-A361 WeakPolarHBondContact OG-CB 3.32Å; S359-A361 PolarHBondContact OG-N 3.02Å; A361-L363 HydrophobicContact CB-CD1 4.33Å; A361-L363 HydrophobicContact CB-CD2 4Å; A361-L363 HydrophobicContact CB-CG 3.97Å; A361-L363 PolarHBondContact O-N 2.62Å; A361-V394 HydrophobicContact CB-CG1 3.78Å; A361-Q400 VanDerWaalsContact CB-O 3.24Å; A361-Q400 WeakPolarHBondContact CB-O 3.43Å
362L97.9Very high98.1Very high12 Ų1231.7 Ų31.76%0.06317%0.173CC..  trans-72.5106.6172.7-178.564.7000109D76 T360 G402 H403 L406 R424D76-L362 WeakPolarHBondContact OD1-CD1 3.4Å; T360-L362 PolarHBondContact O-N 2.8Å; L362-G402 CarbonylContact O-C 3.53Å; L362-G402 WeakPolarHBondContact O-CA 3.47Å; L362-H403 HydrophobicContact CB-CB 4.49Å; L362-H403 HydrophobicContact CD2-CB 4.09Å; L362-H403 HydrophobicContact CG-CB 4.14Å; L362-H403 PolarHBondContact O-CD2 3.27Å; L362-H403 PolarHBondContact O-N 3.17Å; L362-L406 HydrophobicContact CD1-CD1 3.58Å; L362-L406 HydrophobicContact CD1-CG 4.33Å; L362-L406 HydrophobicContact CD2-CD1 4.2Å; L362-L406 HydrophobicContact CD2-CG 4.04Å; L362-L406 HydrophobicContact CG-CD1 3.73Å; L362-L406 HydrophobicContact CG-CG 4.04Å; L362-R424 HydrophobicContact CD1-CG 4.32Å; L362-R424 HydrophobicContact CD2-CG 3.93Å
363L98.5Very high98.2Very high0 Ų024.7 Ų24.70%015%0.147CC..EExtended strand (participates in β ladder)trans-128.7164.9-176.6-55-178.8000111.6F74 D76 F77 H78 A361 D367 V391 V394F74-L363 HydrophobicContact CD1-CD1 3.53Å; F74-L363 HydrophobicContact CE1-CD1 3.42Å; F74-L363 VanDerWaalsContact CE1-CD1 3.42Å; F74-L363 HydrophobicContact CG-CD1 4.3Å; F74-L363 HydrophobicContact CZ-CD1 4.11Å; D76-L363 PolarHBondContact O-N 2.91Å; F77-L363 WeakPolarHBondContact CA-O 3.09Å; F77-L363 HydrophobicContact CD2-CB 3.61Å; F77-L363 HydrophobicContact CD2-CD1 4.41Å; F77-L363 HydrophobicContact CE2-CB 3.92Å; H78-L363 PolarHBondContact N-O 2.79Å; A361-L363 HydrophobicContact CB-CD1 4.33Å; A361-L363 HydrophobicContact CB-CD2 4Å; A361-L363 HydrophobicContact CB-CG 3.97Å; A361-L363 PolarHBondContact O-N 2.62Å; L363-D367 WeakPolarHBondContact CA-OD2 3.36Å; L363-V391 HydrophobicContact CD1-CG2 4.43Å; L363-V391 HydrophobicContact CD2-CB 4.15Å; L363-V391 HydrophobicContact CD2-CG1 3.61Å; L363-V394 HydrophobicContact CD1-CG1 4.35Å
364S98.7Very high98.2Very high3 Ų326.4 Ų26.42%0.02116%0.161CC..EExtended strand (participates in β ladder)trans-136.2157.3177.8-177.80000112.8F77 H78 L366 D367F77-S364 VanDerWaalsContact CZ-C 3.44Å; H78-S364 CarbonylContact O-C 3.49Å; H78-S364 WeakPolarHBondContact O-CA 3.38Å; H78-S364 WeakPolarHBondContact O-CB 3.49Å; H78-S364 PolarHBondContact O-OG 3.48Å; S364-L366 PolarHBondContact O-N 3.42Å; S364-L366 VanDerWaalsContact O-N 3.09Å; S364-L366 PolarHBondContact OG-N 2.97Å; S364-D367 PolarHBondContact N-OD2 3.39Å; S364-D367 VanDerWaalsContact O-CB 3.25Å; S364-D367 WeakPolarHBondContact O-CB 3.37Å; S364-D367 PolarHBondContact O-N 2.89Å
365V98.5Very high98.2Very high0 Ų025.4 Ų25.40%015%0.154CC..G310 helixtrans-48.8-30.2164167.50000112.2F77 H78 L91 T300 D367 I368F77-V365 HydrophobicContact CE1-CB 4.45Å; F77-V365 HydrophobicContact CE1-CG2 3.61Å; F77-V365 HydrophobicContact CZ-CG2 4.2Å; H78-V365 PolarHBondContact O-N 2.93Å; L91-V365 HydrophobicContact CB-CG1 3.41Å; L91-V365 VanDerWaalsContact CB-CG1 3.41Å; L91-V365 HydrophobicContact CD1-CG1 3.86Å; L91-V365 HydrophobicContact CG-CG1 3.8Å; T300-V365 HydrophobicContact CG2-CG2 4.17Å; V365-D367 PolarHBondContact O-N 3.4Å; V365-I368 HydrophobicContact CG1-CD1 4.45Å; V365-I368 WeakPolarHBondContact O-CB 3.02Å; V365-I368 PolarHBondContact O-N 3.03Å
366L98.7Very high98.2Very high8 Ų821 Ų214%0.04213%0.127CC..G310 helixtrans-55.9-32174.1-69.3163.8000112.9A80 L96 S364 I368 P370 D387 G388A80-L366 HydrophobicContact CB-CD1 4.31Å; A80-L366 HydrophobicContact CB-CD2 4.05Å; A80-L366 HydrophobicContact CB-CG 3.84Å; L96-L366 HydrophobicContact CD2-CD1 3.89Å; L96-L366 HydrophobicContact CD2-CD2 4.48Å; L96-L366 HydrophobicContact CG-CD1 4.23Å; S364-L366 PolarHBondContact O-N 3.42Å; S364-L366 VanDerWaalsContact O-N 3.09Å; S364-L366 PolarHBondContact OG-N 2.97Å; L366-I368 VanDerWaalsContact C-N 3.27Å; L366-I368 PolarHBondContact O-N 3.33Å; L366-P370 WeakPolarHBondContact O-CD 3.4Å; L366-D387 HydrophobicContact CD1-CB 3.96Å; L366-D387 HydrophobicContact CD2-CB 4.27Å; L366-G388 WeakPolarHBondContact O-CA 3.35Å
367D98.8Very high98.2Very high0 Ų020.9 Ų20.90%012%0.122CC..G310 helixtrans-73.6-20-175.2-58.3-33.3000112.8L363 S364 V365 F369 P370 T371 G388 V389 V391 H403L363-D367 WeakPolarHBondContact CA-OD2 3.36Å; S364-D367 PolarHBondContact N-OD2 3.39Å; S364-D367 VanDerWaalsContact O-CB 3.25Å; S364-D367 WeakPolarHBondContact O-CB 3.37Å; S364-D367 PolarHBondContact O-N 2.89Å; V365-D367 PolarHBondContact O-N 3.4Å; D367-F369 VanDerWaalsContact C-N 3.3Å; D367-F369 PolarHBondContact O-N 3.33Å; D367-P370 WeakPolarHBondContact O-CD 2.95Å; D367-T371 WeakPolarHBondContact O-CB 3.28Å; D367-T371 PolarHBondContact O-N 3.12Å; D367-T371 VanDerWaalsContact O-N 3.08Å; D367-T371 PolarHBondContact O-OG1 3.46Å; D367-G388 WeakPolarHBondContact OD1-CA 3.28Å; D367-V389 WeakPolarHBondContact CB-O 3.43Å; D367-V389 PolarHBondContact OD1-N 2.84Å; D367-V391 HydrophobicContact CB-CG1 3.9Å; D367-V391 HydrophobicContact CB-CG2 4.15Å; D367-H403 VanDerWaalsContact CG-NE2 3.27Å; D367-H403 IonicContact OD1-CD2 2.92Å; D367-H403 IonicContact OD1-CE1 2.68Å; D367-H403 PolarHBondContact OD1-CE1 3.02Å; D367-H403 IonicContact OD1-NE2 2.89Å; D367-H403 PolarHBondContact OD1-NE2 2.9Å; D367-H403 IonicContact OD2-CD2 2.7Å; D367-H403 PolarHBondContact OD2-CD2 3.02Å; D367-H403 IonicContact OD2-NE2 2.93Å; D367-H403 PolarHBondContact OD2-NE2 3.32Å; D367-H403 VanDerWaalsContact OD2-NE2 3.07Å
368I98.9Very high98.2Very high0 Ų019.7 Ų19.70%012%0.118CC..Hα-helixtrans-58.2-45.4179.8-65.7177.5000110I40 L91 L121 W298 T300 V365 L366 V372I40-I368 HydrophobicContact CD1-CG2 3.71Å; I40-I368 HydrophobicContact CG1-CG2 4.43Å; I40-I368 HydrophobicContact CG2-CG2 4.44Å; L91-I368 HydrophobicContact CD1-CD1 3.95Å; L91-I368 HydrophobicContact CD2-CG2 4.41Å; L91-I368 HydrophobicContact CG-CD1 4.16Å; L91-I368 HydrophobicContact CG-CG2 4.45Å; L121-I368 HydrophobicContact CD2-CG2 4.45Å; W298-I368 HydrophobicContact CD2-CD1 4.45Å; W298-I368 HydrophobicContact CD2-CG1 4.04Å; W298-I368 HydrophobicContact CE3-CG1 3.9Å; W298-I368 HydrophobicContact CE3-CG2 4.49Å; W298-I368 HydrophobicContact CH2-CG1 4.15Å; W298-I368 HydrophobicContact CZ2-CG1 4.25Å; W298-I368 HydrophobicContact CZ3-CB 4.44Å; W298-I368 HydrophobicContact CZ3-CG1 3.98Å; T300-I368 HydrophobicContact CG2-CD1 4.12Å; V365-I368 HydrophobicContact CG1-CD1 4.45Å; V365-I368 WeakPolarHBondContact O-CB 3.02Å; V365-I368 PolarHBondContact O-N 3.03Å; L366-I368 VanDerWaalsContact C-N 3.27Å; L366-I368 PolarHBondContact O-N 3.33Å; I368-V372 HydrophobicContact CG2-CG2 4.16Å; I368-V372 VanDerWaalsContact O-CB 3.27Å; I368-V372 WeakPolarHBondContact O-CB 3.15Å; I368-V372 WeakPolarHBondContact O-CG2 3.32Å; I368-V372 PolarHBondContact O-N 3.41Å
369F98.9Very high98.2Very high0 Ų020.9 Ų20.90%013%0.129CC..Hα-helixtrans-59.1-63.8-178.5-176.3-76.8000112.7L92 T93 L121 V124 D367 T371 V372 V373 L380 P381 F386L92-F369 WeakPolarHBondContact O-CD2 3.19Å; L92-F369 WeakPolarHBondContact O-CE2 3.34Å; T93-F369 VanDerWaalsContact C-CD2 3.48Å; L121-F369 HydrophobicContact CB-CD2 3.77Å; L121-F369 HydrophobicContact CB-CE2 4.06Å; L121-F369 HydrophobicContact CD1-CD2 4.22Å; V124-F369 HydrophobicContact CG2-CZ 3.94Å; D367-F369 VanDerWaalsContact C-N 3.3Å; D367-F369 PolarHBondContact O-N 3.33Å; F369-T371 VanDerWaalsContact C-N 3.31Å; F369-T371 PolarHBondContact O-N 3.32Å; F369-V372 PolarHBondContact O-N 2.03Å; F369-V373 HydrophobicContact CD1-CG2 4.15Å; F369-V373 HydrophobicContact CE1-CG2 3.97Å; F369-V373 HydrophobicContact CZ-CG2 4.43Å; F369-V373 WeakPolarHBondContact O-CB 3.49Å; F369-V373 VanDerWaalsContact O-CG2 3.26Å; F369-V373 WeakPolarHBondContact O-CG2 3.42Å; F369-V373 PolarHBondContact O-N 2.92Å; F369-L380 HydrophobicContact CD1-CD2 3.92Å; F369-L380 HydrophobicContact CE1-CD2 3.65Å; F369-P381 HydrophobicContact CZ-CG 4.13Å; F369-F386 HydrophobicContact CD1-CD1 4.11Å; F369-F386 AromaticContact CD1-CE1 3.94Å; F369-F386 HydrophobicContact CD1-CE1 3.94Å; F369-F386 HydrophobicContact CE1-CD1 4.07Å; F369-F386 AromaticContact CE1-CE1 3.43Å; F369-F386 HydrophobicContact CE1-CE1 3.43Å; F369-F386 VanDerWaalsContact CE1-CE1 3.43Å; F369-F386 HydrophobicContact CE1-CZ 4.12Å; F369-F386 HydrophobicContact CZ-CE1 4.01Å
370P98.8Very high98.2Very high7 Ų723.8 Ų23.85%0.04514%0.144CC..Hα-helixtrans-64.8-34-176.825.5-35.3000112.9L366 D367 V373 A374 L380 V389L366-P370 WeakPolarHBondContact O-CD 3.4Å; D367-P370 WeakPolarHBondContact O-CD 2.95Å; P370-V373 PolarHBondContact O-N 2.97Å; P370-A374 WeakPolarHBondContact O-CB 3.24Å; P370-A374 PolarHBondContact O-N 2.88Å; P370-L380 HydrophobicContact CB-CD2 4.11Å; P370-V389 VanDerWaalsContact CG-C 3.48Å; P370-V389 WeakPolarHBondContact CG-O 3.41Å
371T98.8Very high98.2Very high0 Ų020.2 Ų20.20%012%0.122CC..Hα-helixtrans-64.9-47.4177.4-57.20000111.4W298 D367 F369 A374 L375 V389 V391 L395W298-T371 HydrophobicContact CZ3-CG2 4.05Å; D367-T371 WeakPolarHBondContact O-CB 3.28Å; D367-T371 PolarHBondContact O-N 3.12Å; D367-T371 VanDerWaalsContact O-N 3.08Å; D367-T371 PolarHBondContact O-OG1 3.46Å; F369-T371 VanDerWaalsContact C-N 3.31Å; F369-T371 PolarHBondContact O-N 3.32Å; T371-A374 PolarHBondContact O-N 3.43Å; T371-L375 HydrophobicContact CG2-CD1 4.04Å; T371-L375 HydrophobicContact CG2-CG 4.47Å; T371-L375 WeakPolarHBondContact O-CB 3.09Å; T371-L375 VanDerWaalsContact O-CG 3.26Å; T371-L375 WeakPolarHBondContact O-CG 3.27Å; T371-L375 PolarHBondContact O-N 3.02Å; T371-V389 PolarHBondContact OG1-O 3.17Å; T371-V391 HydrophobicContact CG2-CG2 4.17Å; T371-V391 WeakPolarHBondContact OG1-CG2 3.41Å; T371-V391 PolarHBondContact OG1-N 2.69Å; T371-L395 HydrophobicContact CG2-CD1 3.56Å
372V98.9Very high98Very high0 Ų028 Ų280%016%0.158CC..Hα-helixtrans-66.2-40.2178.6172.70000110.9F38 I40 L121 L125 I368 F369 A374 L375 A376F38-V372 HydrophobicContact CD1-CG1 4.05Å; F38-V372 HydrophobicContact CD1-CG2 4.33Å; F38-V372 HydrophobicContact CD2-CG1 3.66Å; F38-V372 HydrophobicContact CE1-CG1 4.1Å; F38-V372 HydrophobicContact CE2-CG1 3.71Å; F38-V372 HydrophobicContact CG-CG1 3.81Å; F38-V372 HydrophobicContact CZ-CG1 3.92Å; I40-V372 HydrophobicContact CD1-CG2 4.26Å; L121-V372 HydrophobicContact CD1-CB 4.07Å; L121-V372 HydrophobicContact CD1-CG1 3.89Å; L121-V372 HydrophobicContact CD2-CB 4.3Å; L121-V372 HydrophobicContact CD2-CG1 4.21Å; L121-V372 HydrophobicContact CG-CG1 4.45Å; L125-V372 HydrophobicContact CD1-CG1 3.76Å; L125-V372 HydrophobicContact CD2-CG1 4.39Å; I368-V372 HydrophobicContact CG2-CG2 4.16Å; I368-V372 VanDerWaalsContact O-CB 3.27Å; I368-V372 WeakPolarHBondContact O-CB 3.15Å; I368-V372 WeakPolarHBondContact O-CG2 3.32Å; I368-V372 PolarHBondContact O-N 3.41Å; F369-V372 PolarHBondContact O-N 2.03Å; V372-A374 PolarHBondContact O-N 3.01Å; V372-L375 PolarHBondContact O-N 3.17Å; V372-A376 VanDerWaalsContact O-CB 3.23Å; V372-A376 WeakPolarHBondContact O-CB 3.46Å; V372-A376 PolarHBondContact O-N 3.15Å
373V98.8Very high97.7Very high2 Ų230.4 Ų30.41%0.01219%0.187CC..Hα-helixtrans-59.6-44.7174.6171.10000111.4L121 V124 F369 P370 A376 Q377 A378 L380L121-V373 HydrophobicContact CD1-CG2 3.85Å; V124-V373 HydrophobicContact CB-CG2 4.38Å; V124-V373 HydrophobicContact CG1-CG1 4.22Å; V124-V373 HydrophobicContact CG1-CG2 3.77Å; F369-V373 HydrophobicContact CD1-CG2 4.15Å; F369-V373 HydrophobicContact CE1-CG2 3.97Å; F369-V373 HydrophobicContact CZ-CG2 4.43Å; F369-V373 WeakPolarHBondContact O-CB 3.49Å; F369-V373 VanDerWaalsContact O-CG2 3.26Å; F369-V373 WeakPolarHBondContact O-CG2 3.42Å; F369-V373 PolarHBondContact O-N 2.92Å; P370-V373 PolarHBondContact O-N 2.97Å; V373-A376 PolarHBondContact O-N 3.06Å; V373-Q377 PolarHBondContact O-N 3.35Å; V373-A378 HydrophobicContact CG1-CB 3.96Å; V373-A378 PolarHBondContact O-N 2.88Å; V373-L380 HydrophobicContact CB-CD2 4.18Å; V373-L380 HydrophobicContact CG1-CD2 3.98Å; V373-L380 HydrophobicContact CG1-CG 4.32Å; V373-L380 HydrophobicContact CG2-CD2 4.39Å
374A98.4Very high97.5Very high41 Ų4132.2 Ų32.234%0.33919%0.193SC..Hα-helixtrans-63.6-48.1177.500000111.8P370 T371 V372 A376 Q377 D390P370-A374 WeakPolarHBondContact O-CB 3.24Å; P370-A374 PolarHBondContact O-N 2.88Å; T371-A374 PolarHBondContact O-N 3.43Å; V372-A374 PolarHBondContact O-N 3.01Å; A374-A376 VanDerWaalsContact C-N 3.25Å; A374-A376 PolarHBondContact O-N 3.29Å; A374-Q377 WeakPolarHBondContact O-CA 3.23Å; A374-Q377 PolarHBondContact O-N 3.03Å; A374-D390 HydrophobicContact CB-CB 4.38Å; A374-D390 WeakPolarHBondContact CB-OD2 3.35Å
375L98.3Very high97.4Very high22 Ų2236.9 Ų36.912%0.11521%0.211CC..Hα-helixtrans-63-31177.9-68.7175.8000112.8P36 F38 F296 W349 T371 V372 Q377 F396P36-L375 WeakPolarHBondContact CD-O 3.26Å; P36-L375 HydrophobicContact CG-CB 4.47Å; F38-L375 HydrophobicContact CE1-CB 3.82Å; F38-L375 HydrophobicContact CE1-CD1 4.12Å; F38-L375 HydrophobicContact CZ-CB 3.7Å; F296-L375 HydrophobicContact CD1-CD1 4.18Å; F296-L375 HydrophobicContact CE1-CD1 4.39Å; W349-L375 HydrophobicContact CZ3-CD1 4.31Å; W349-L375 HydrophobicContact CZ3-CD2 4.38Å; T371-L375 HydrophobicContact CG2-CD1 4.04Å; T371-L375 HydrophobicContact CG2-CG 4.47Å; T371-L375 WeakPolarHBondContact O-CB 3.09Å; T371-L375 VanDerWaalsContact O-CG 3.26Å; T371-L375 WeakPolarHBondContact O-CG 3.27Å; T371-L375 PolarHBondContact O-N 3.02Å; V372-L375 PolarHBondContact O-N 3.17Å; L375-Q377 PolarHBondContact O-N 3.48Å; L375-F396 HydrophobicContact CD2-CE2 4.06Å; L375-F396 HydrophobicContact CD2-CZ 3.6Å
376A98.4Very high97.3Very high0 Ų039.1 Ų39.10%022%0.22CC..THydrogen-bonded Turntrans-75-6.4174.400000113.9K35 F38 L125 Y130 V372 V373 A374 A378K35-A376 WeakPolarHBondContact CE-O 3.02Å; K35-A376 PolarHBondContact NZ-O 2.99Å; F38-A376 HydrophobicContact CE2-CB 3.88Å; F38-A376 HydrophobicContact CZ-CB 4.2Å; L125-A376 HydrophobicContact CD2-CB 3.31Å; Y130-A376 HydrophobicContact CE2-CB 3.87Å; V372-A376 VanDerWaalsContact O-CB 3.23Å; V372-A376 WeakPolarHBondContact O-CB 3.46Å; V372-A376 PolarHBondContact O-N 3.15Å; V373-A376 PolarHBondContact O-N 3.06Å; A374-A376 VanDerWaalsContact C-N 3.25Å; A374-A376 PolarHBondContact O-N 3.29Å; A376-A378 HydrophobicContact CB-CB 4.23Å; A376-A378 PolarHBondContact O-N 3.06Å
377Q97.4Very high97.3Very high120 Ų12040 Ų4056%0.56123%0.225SC*.THydrogen-bonded Turntrans54.138.4-169.9-55.3169.723.600111.2V373 A374 L375V373-Q377 PolarHBondContact O-N 3.35Å; A374-Q377 WeakPolarHBondContact O-CA 3.23Å; A374-Q377 PolarHBondContact O-N 3.03Å; L375-Q377 PolarHBondContact O-N 3.48Å
378A97.4Very high97.2Very high25 Ų2540.3 Ų40.321%0.20723%0.228CC..  trans-97.9177.5173.900000110V124 A128 V373 A376V124-A378 HydrophobicContact CG1-CB 4Å; A128-A378 HydrophobicContact CB-CB 3.93Å; V373-A378 HydrophobicContact CG1-CB 3.96Å; V373-A378 PolarHBondContact O-N 2.88Å; A376-A378 HydrophobicContact CB-CB 4.23Å; A376-A378 PolarHBondContact O-N 3.06Å
379S97Very high97.2Very high95 Ų9543.4 Ų43.466%0.66425%0.247SC*.  trans-114140.7178.6-61.40000110.1
380L97.5Very high97.1Very high64 Ų6447.1 Ų47.134%0.33527%0.267SS..PPolyproline II helixtrans-62.1142.8171.9-68.3173.9000110.2F369 P370 V373 Q382 F386F369-L380 HydrophobicContact CD1-CD2 3.92Å; F369-L380 HydrophobicContact CE1-CD2 3.65Å; P370-L380 HydrophobicContact CB-CD2 4.11Å; V373-L380 HydrophobicContact CB-CD2 4.18Å; V373-L380 HydrophobicContact CG1-CD2 3.98Å; V373-L380 HydrophobicContact CG1-CG 4.32Å; V373-L380 HydrophobicContact CG2-CD2 4.39Å; L380-Q382 PolarHBondContact O-N 3.11Å; L380-Q382 PolarHBondContact O-NE2 2.81Å; L380-F386 HydrophobicContact CB-CD2 4.46Å; L380-F386 HydrophobicContact CB-CE2 3.89Å; L380-F386 HydrophobicContact CB-CZ 4.26Å; L380-F386 HydrophobicContact CD1-CD2 4.12Å; L380-F386 HydrophobicContact CD1-CE2 4.38Å; L380-F386 HydrophobicContact CD2-CE1 4.42Å; L380-F386 HydrophobicContact CD2-CE2 4.41Å; L380-F386 HydrophobicContact CD2-CZ 4.36Å; L380-F386 HydrophobicContact CG-CE2 4.47Å
381P95.9Very high97.1Very high23 Ų2347 Ų4715%0.14927%0.266CS..PPolyproline II helixtrans-50.4133.1170.5-26.130.9000111.9T119 V124 F369 F386T119-P381 HydrophobicContact CG2-CG 4.04Å; V124-P381 HydrophobicContact CG2-CG 3.95Å; F369-P381 HydrophobicContact CZ-CG 4.13Å; P381-F386 HydrophobicContact CB-CZ 4.06Å; P381-F386 HydrophobicContact CG-CZ 3.98Å; P381-F386 WeakPolarHBondContact O-CE2 3.25Å
382Q94.3Very high97Very high165 Ų16547.6 Ų47.677%0.77127%0.27SS*.THydrogen-bonded Turntrans-80.7158.2-177.9-60.6-60.9-59.800111.7L380 R384L380-Q382 PolarHBondContact O-N 3.11Å; L380-Q382 PolarHBondContact O-NE2 2.81Å; Q382-R384 VanDerWaalsContact C-N 3.28Å; Q382-R384 PolarHBondContact O-N 3.24Å
383G91.9Very high96.9Very high64 Ų6451.7 Ų51.766%0.6629%0.289SS*.THydrogen-bonded Turntrans71.519.7173.800000114.9
384R92.8Very high96.9Very high37 Ų3751.9 Ų51.914%0.1429%0.29CS..  trans-137.6145.8177.9-70.8-177.7-178.5-85.8-10.5109.8N117 E118 Q382 F386 S499N117-R384 PolarHBondContact ND2-NH2 3.28Å; N117-R384 PolarHBondContact O-NH2 3.18Å; E118-R384 IonicContact OE1-CZ 2.86Å; E118-R384 IonicContact OE1-NH1 3.28Å; E118-R384 PolarHBondContact OE1-NH1 3.03Å; E118-R384 IonicContact OE2-CZ 3.95Å; E118-R384 IonicContact OE2-NE 3.04Å; E118-R384 IonicContact OE2-NH1 3.53Å; E118-R384 PolarHBondContact OE2-NH1 3.02Å; Q382-R384 VanDerWaalsContact C-N 3.28Å; Q382-R384 PolarHBondContact O-N 3.24Å; R384-F386 HydrophobicContact CB-CE2 4.46Å; R384-S499 PolarHBondContact NH1-OG 2.79Å
385R96.2Very high96.8Very high102 Ų10250 Ų5039%0.38528%0.275SS..  trans-87.6149.7168.7-59.3-176.6-166.5-139.31.9110.7R95 D492 D496R95-R385 WeakPolarHBondContact CG-O 3.45Å; R95-R385 PolarHBondContact NH1-O 3.18Å; R385-D492 WeakPolarHBondContact CD-OD1 3.4Å; R385-D492 WeakPolarHBondContact CD-OD2 3.37Å; R385-D492 IonicContact CZ-OD1 3.59Å; R385-D492 IonicContact NE-OD1 3.7Å; R385-D492 IonicContact NH1-OD1 2.71Å; R385-D492 PolarHBondContact NH1-OD1 2.92Å; R385-D496 HydrophobicContact CG-CB 4.33Å; R385-D496 PolarHBondContact N-OD1 2.75Å
386F97.7Very high96.8Very high46 Ų4650.7 Ų50.720%0.20228%0.277CS..  trans-117.8139.7176.3-66.6-88.7000109T93 R95 F369 L380 P381 R384T93-F386 WeakPolarHBondContact O-CD1 3.4Å; T93-F386 WeakPolarHBondContact O-CE1 3.37Å; R95-F386 HydrophobicContact CG-CD1 4.15Å; R95-F386 HydrophobicContact CG-CE1 4.49Å; F369-F386 HydrophobicContact CD1-CD1 4.11Å; F369-F386 AromaticContact CD1-CE1 3.94Å; F369-F386 HydrophobicContact CD1-CE1 3.94Å; F369-F386 HydrophobicContact CE1-CD1 4.07Å; F369-F386 AromaticContact CE1-CE1 3.43Å; F369-F386 HydrophobicContact CE1-CE1 3.43Å; F369-F386 VanDerWaalsContact CE1-CE1 3.43Å; F369-F386 HydrophobicContact CE1-CZ 4.12Å; F369-F386 HydrophobicContact CZ-CE1 4.01Å; L380-F386 HydrophobicContact CB-CD2 4.46Å; L380-F386 HydrophobicContact CB-CE2 3.89Å; L380-F386 HydrophobicContact CB-CZ 4.26Å; L380-F386 HydrophobicContact CD1-CD2 4.12Å; L380-F386 HydrophobicContact CD1-CE2 4.38Å; L380-F386 HydrophobicContact CD2-CE1 4.42Å; L380-F386 HydrophobicContact CD2-CE2 4.41Å; L380-F386 HydrophobicContact CD2-CZ 4.36Å; L380-F386 HydrophobicContact CG-CE2 4.47Å; P381-F386 HydrophobicContact CB-CZ 4.06Å; P381-F386 HydrophobicContact CG-CZ 3.98Å; P381-F386 WeakPolarHBondContact O-CE2 3.25Å; R384-F386 HydrophobicContact CB-CE2 4.46Å
387D98.2Very high96.6Very high28 Ų2852.5 Ų52.515%0.1530%0.296CS..SBendtrans-93-23.6177.2-57.3-67.9000111.3G94 R95 L96 R99 L366G94-D387 PolarHBondContact O-N 3.16Å; R95-D387 WeakPolarHBondContact CA-OD2 3.05Å; L96-D387 WeakPolarHBondContact CB-OD2 3.38Å; L96-D387 HydrophobicContact CD1-CB 4.28Å; L96-D387 HydrophobicContact CG-CB 4.03Å; L96-D387 WeakPolarHBondContact CG-OD2 3.45Å; L96-D387 PolarHBondContact N-OD2 2.99Å; R99-D387 WeakPolarHBondContact CD-OD2 3.44Å; R99-D387 IonicContact CZ-OD1 3.55Å; R99-D387 VanDerWaalsContact CZ-OD1 3.29Å; R99-D387 IonicContact NE-OD1 3.12Å; R99-D387 PolarHBondContact NE-OD1 2.04Å; R99-D387 IonicContact NE-OD2 2.93Å; R99-D387 PolarHBondContact NE-OD2 3.2Å; R99-D387 IonicContact NH2-OD1 3.46Å; R99-D387 PolarHBondContact NH2-OD1 2.93Å; L366-D387 HydrophobicContact CD1-CB 3.96Å; L366-D387 HydrophobicContact CD2-CB 4.27Å
388G97.8Very high96.5Very high6 Ų654.8 Ų54.86%0.06230%0.299CS..  trans-76.4157169.100000112.7G94 L366 D367G94-G388 PolarHBondContact O-N 2.69Å; L366-G388 WeakPolarHBondContact O-CA 3.35Å; D367-G388 WeakPolarHBondContact OD1-CA 3.28Å
389V96.9Very high96.2Very high64 Ų6455.4 Ų55.439%0.38830%0.302SS..  trans-122.4156.9173.1-63.10000111.7D367 P370 T371 V391D367-V389 WeakPolarHBondContact CB-O 3.43Å; D367-V389 PolarHBondContact OD1-N 2.84Å; P370-V389 VanDerWaalsContact CG-C 3.48Å; P370-V389 WeakPolarHBondContact CG-O 3.41Å; T371-V389 PolarHBondContact OG1-O 3.17Å; V389-V391 HydrophobicContact CG2-CG1 3.81Å; V389-V391 PolarHBondContact O-N 3.45Å
390D97.8Very high95.4Very high78 Ų7856.6 Ų56.642%0.41730%0.297SS..  trans-70.3114.6170.4175.111.9000110A374 S392A374-D390 HydrophobicContact CB-CB 4.38Å; A374-D390 WeakPolarHBondContact CB-OD2 3.35Å; D390-S392 VanDerWaalsContact CG-OG 3.31Å; D390-S392 WeakPolarHBondContact OD1-CB 3.42Å; D390-S392 PolarHBondContact OD1-N 3.09Å; D390-S392 PolarHBondContact OD1-OG 2.68Å; D390-S392 PolarHBondContact OD2-OG 3.01Å
391V98.1Very high94.8Very high4 Ų458.2 Ų58.22%0.02431%0.311CS..  trans-10718.9-179.1-54.90000112.5W298 L363 D367 T371 V389 E393 V394 L395W298-V391 HydrophobicContact CH2-CG2 3.71Å; W298-V391 HydrophobicContact CZ2-CG2 4.47Å; L363-V391 HydrophobicContact CD1-CG2 4.43Å; L363-V391 HydrophobicContact CD2-CB 4.15Å; L363-V391 HydrophobicContact CD2-CG1 3.61Å; D367-V391 HydrophobicContact CB-CG1 3.9Å; D367-V391 HydrophobicContact CB-CG2 4.15Å; T371-V391 HydrophobicContact CG2-CG2 4.17Å; T371-V391 WeakPolarHBondContact OG1-CG2 3.41Å; T371-V391 PolarHBondContact OG1-N 2.69Å; V389-V391 HydrophobicContact CG2-CG1 3.81Å; V389-V391 PolarHBondContact O-N 3.45Å; V391-E393 PolarHBondContact O-N 3.12Å; V391-V394 HydrophobicContact CB-CB 4.37Å; V391-V394 HydrophobicContact CB-CG2 4.44Å; V391-V394 WeakPolarHBondContact O-CA 3.26Å; V391-V394 WeakPolarHBondContact O-CB 3.4Å; V391-V394 PolarHBondContact O-N 2.64Å; V391-L395 HydrophobicContact CG2-CD1 4.4Å; V391-L395 HydrophobicContact CG2-CG 4.44Å; V391-L395 PolarHBondContact O-N 3.27Å
392S97.6Very high94.6Very high14 Ų1458.2 Ų58.210%0.09832%0.315CS..Hα-helixtrans-53.2-38.8178.655.80000113.2D390 V394 L395 F396D390-S392 VanDerWaalsContact CG-OG 3.31Å; D390-S392 WeakPolarHBondContact OD1-CB 3.42Å; D390-S392 PolarHBondContact OD1-N 3.09Å; D390-S392 PolarHBondContact OD1-OG 2.68Å; D390-S392 PolarHBondContact OD2-OG 3.01Å; S392-V394 VanDerWaalsContact C-N 3.32Å; S392-V394 PolarHBondContact O-N 3.48Å; S392-L395 WeakPolarHBondContact O-CB 3.36Å; S392-L395 PolarHBondContact O-N 3.2Å; S392-F396 WeakPolarHBondContact O-CD2 3.18Å; S392-F396 VanDerWaalsContact O-CG 3.23Å; S392-F396 WeakPolarHBondContact O-CG 3.49Å; S392-F396 PolarHBondContact O-N 2.85Å
393E97.4Very high94.7Very high85 Ų8551.8 Ų51.840%0.39729%0.285SS..Hα-helixtrans-68.7-29.2177.1-68.5-63.7114.500113V391 G397 R398 S399V391-E393 PolarHBondContact O-N 3.12Å; E393-G397 PolarHBondContact O-N 3.43Å; E393-R398 HydrophobicContact CB-CB 4.47Å; E393-R398 WeakPolarHBondContact O-CA 3.41Å; E393-R398 PolarHBondContact O-N 3.41Å; E393-R398 IonicContact OE1-NH1 3.9Å; E393-R398 PolarHBondContact OE1-NH1 3.32Å; E393-R398 VanDerWaalsContact OE2-CB 3.23Å; E393-R398 WeakPolarHBondContact OE2-CB 3.48Å; E393-R398 WeakPolarHBondContact OE2-CD 3.32Å; E393-R398 IonicContact OE2-NH1 2.72Å; E393-S399 PolarHBondContact O-N 2.91Å
394V97.5Very high94.9Very high6 Ų656.8 Ų56.84%0.03628%0.284CS..Hα-helixtrans-70.4-46.4169.9-179.20000109.6M72 F74 A361 L363 V391 S392 F396 G397M72-V394 WeakPolarHBondContact CE-O 3.38Å; F74-V394 HydrophobicContact CE1-CG1 4.06Å; A361-V394 HydrophobicContact CB-CG1 3.78Å; L363-V394 HydrophobicContact CD1-CG1 4.35Å; V391-V394 HydrophobicContact CB-CB 4.37Å; V391-V394 HydrophobicContact CB-CG2 4.44Å; V391-V394 WeakPolarHBondContact O-CA 3.26Å; V391-V394 WeakPolarHBondContact O-CB 3.4Å; V391-V394 PolarHBondContact O-N 2.64Å; S392-V394 VanDerWaalsContact C-N 3.32Å; S392-V394 PolarHBondContact O-N 3.48Å; V394-F396 PolarHBondContact O-N 3.34Å; V394-G397 PolarHBondContact O-N 3.22Å
395L97.7Very high95.2Very high1 Ų156.7 Ų56.71%0.00529%0.288CS..Hα-helixtrans-57.8-36.3178.1-70.9169000112.6F74 F296 W298 A347 P354 T371 V391 S392 G397F74-L395 HydrophobicContact CE2-CD2 4.3Å; F74-L395 HydrophobicContact CZ-CD2 3.82Å; F296-L395 HydrophobicContact CE1-CD1 4.08Å; F296-L395 HydrophobicContact CE2-CD1 4.41Å; F296-L395 HydrophobicContact CE2-CD2 4.11Å; F296-L395 HydrophobicContact CZ-CD1 3.68Å; F296-L395 HydrophobicContact CZ-CD2 3.79Å; F296-L395 HydrophobicContact CZ-CG 4.41Å; W298-L395 HydrophobicContact CH2-CD1 4.26Å; W298-L395 HydrophobicContact CZ3-CD1 4.12Å; A347-L395 HydrophobicContact CB-CD2 3.48Å; A347-L395 VanDerWaalsContact CB-CD2 3.48Å; P354-L395 VanDerWaalsContact CD-O 3.23Å; P354-L395 WeakPolarHBondContact CD-O 3.3Å; T371-L395 HydrophobicContact CG2-CD1 3.56Å; V391-L395 HydrophobicContact CG2-CD1 4.4Å; V391-L395 HydrophobicContact CG2-CG 4.44Å; V391-L395 PolarHBondContact O-N 3.27Å; S392-L395 WeakPolarHBondContact O-CB 3.36Å; S392-L395 PolarHBondContact O-N 3.2Å; L395-G397 VanDerWaalsContact C-N 3.29Å; L395-G397 PolarHBondContact O-N 2.93Å
396F97.6Very high95.2Very high38 Ų3852.2 Ų52.217%0.16727%0.271CS..THydrogen-bonded Turntrans-864.7177.6-57.4-35000114W349 R352 L375 S392 V394 R398W349-F396 HydrophobicContact CE3-CE1 4.19Å; W349-F396 HydrophobicContact CZ3-CE1 4.12Å; W349-F396 HydrophobicContact CZ3-CZ 4.25Å; R352-F396 HydrophobicContact CB-CD1 4.32Å; R352-F396 HydrophobicContact CB-CE1 4.08Å; R352-F396 WeakPolarHBondContact O-CD1 3.18Å; L375-F396 HydrophobicContact CD2-CE2 4.06Å; L375-F396 HydrophobicContact CD2-CZ 3.6Å; S392-F396 WeakPolarHBondContact O-CD2 3.18Å; S392-F396 VanDerWaalsContact O-CG 3.23Å; S392-F396 WeakPolarHBondContact O-CG 3.49Å; S392-F396 PolarHBondContact O-N 2.85Å; V394-F396 PolarHBondContact O-N 3.34Å; F396-R398 VanDerWaalsContact C-N 3.27Å; F396-R398 HydrophobicContact CB-CG 4.27Å; F396-R398 PolarHBondContact O-N 3.17Å
397G94.8Very high95.3Very high38 Ų3851.6 Ų51.639%0.39227%0.268SS..THydrogen-bonded Turntrans69.120.6178.500000114.7E393 V394 L395E393-G397 PolarHBondContact O-N 3.43Å; V394-G397 PolarHBondContact O-N 3.22Å; L395-G397 VanDerWaalsContact C-N 3.29Å; L395-G397 PolarHBondContact O-N 2.93Å
398R94.4Very high95.3Very high168 Ų16850.5 Ų50.563%0.63426%0.263SS*.SBendtrans-96.9-19.2-179-61.7172.3-175.2165.52.2112.7E393 F396E393-R398 HydrophobicContact CB-CB 4.47Å; E393-R398 WeakPolarHBondContact O-CA 3.41Å; E393-R398 PolarHBondContact O-N 3.41Å; E393-R398 IonicContact OE1-NH1 3.9Å; E393-R398 PolarHBondContact OE1-NH1 3.32Å; E393-R398 VanDerWaalsContact OE2-CB 3.23Å; E393-R398 WeakPolarHBondContact OE2-CB 3.48Å; E393-R398 WeakPolarHBondContact OE2-CD 3.32Å; E393-R398 IonicContact OE2-NH1 2.72Å; F396-R398 VanDerWaalsContact C-N 3.27Å; F396-R398 HydrophobicContact CB-CG 4.27Å; F396-R398 PolarHBondContact O-N 3.17Å
399S91.4Very high95.3Very high37 Ų3750.6 Ų50.626%0.25926%0.262SS..  trans-127.2152173.7-172.90000110.7E393 P401E393-S399 PolarHBondContact O-N 2.91Å; S399-P401 WeakPolarHBondContact OG-CD 3.32Å
400Q80.6Confident95.3Very high120 Ų12047.7 Ų47.756%0.56124%0.244SC*.  trans-111.5-39.1176.2-66.1-69-1400113A361A361-Q400 VanDerWaalsContact CB-O 3.24Å; A361-Q400 WeakPolarHBondContact CB-O 3.43Å
401P85.2Confident95.3Very high99 Ų9944.1 Ų44.164%0.64323%0.225SC*.  trans-77.2137.6176.629.1-34.5000111.6S399S399-P401 WeakPolarHBondContact OG-CD 3.32Å
402G90.9Very high95.2Very high22 Ų2245.5 Ų45.523%0.22724%0.24CC..  trans-98-131.3162.900000110.8L362L362-G402 CarbonylContact O-C 3.53Å; L362-G402 WeakPolarHBondContact O-CA 3.47Å
403H96.7Very high95.1Very high31 Ų3145.7 Ų45.714%0.14424%0.242CC..  trans-60.2150.3173.4-71.1-87.4000112.4L362 D367 L406L362-H403 HydrophobicContact CB-CB 4.49Å; L362-H403 HydrophobicContact CD2-CB 4.09Å; L362-H403 HydrophobicContact CG-CB 4.14Å; L362-H403 PolarHBondContact O-CD2 3.27Å; L362-H403 PolarHBondContact O-N 3.17Å; D367-H403 VanDerWaalsContact CG-NE2 3.27Å; D367-H403 IonicContact OD1-CD2 2.92Å; D367-H403 IonicContact OD1-CE1 2.68Å; D367-H403 PolarHBondContact OD1-CE1 3.02Å; D367-H403 IonicContact OD1-NE2 2.89Å; D367-H403 PolarHBondContact OD1-NE2 2.9Å; D367-H403 IonicContact OD2-CD2 2.7Å; D367-H403 PolarHBondContact OD2-CD2 3.02Å; D367-H403 IonicContact OD2-NE2 2.93Å; D367-H403 PolarHBondContact OD2-NE2 3.32Å; D367-H403 VanDerWaalsContact OD2-NE2 3.07Å; H403-L406 HydrophobicContact CB-CD2 3.92Å; H403-L406 HydrophobicContact CB-CG 4.16Å
404R96.2Very high95.1Very high169 Ų16942.2 Ų42.264%0.63823%0.228SC*.SBendtrans-95.4-24.1162.3-68.5-176.863.9-150.7-0.7112.4E426R404-E426 IonicContact CZ-OE1 3.99Å; R404-E426 IonicContact NE-OE1 2.72Å; R404-E426 PolarHBondContact NE-OE1 2.79Å; R404-E426 VanDerWaalsContact NE-OE1 3.16Å; R404-E426 IonicContact NH2-OE1 3.01Å; R404-E426 PolarHBondContact NH2-OE1 3.36Å; R404-E426 PolarHBondContact O-N 2.79Å
405V97.9Very high95.1Very high35 Ų3543.1 Ų43.121%0.21224%0.239CC..EExtended strand (participates in β ladder)trans-136.3132.1-178.7-1700000108.8F407 V423 R424 L425 V485V405-F407 HydrophobicContact CB-CE2 4.5Å; V405-F407 HydrophobicContact CG1-CD2 4.37Å; V405-F407 HydrophobicContact CG1-CE1 3.98Å; V405-F407 HydrophobicContact CG1-CE2 3.66Å; V405-F407 HydrophobicContact CG1-CZ 3.43Å; V405-F407 VanDerWaalsContact CG1-CZ 3.43Å; V405-V423 HydrophobicContact CG1-CG1 4.03Å; V405-R424 CarbonylContact C-O 3.49Å; V405-R424 WeakPolarHBondContact CA-O 3.38Å; V405-R424 WeakPolarHBondContact CG1-O 3.41Å; V405-L425 HydrophobicContact CG2-CD1 3.68Å; V405-V485 HydrophobicContact CG1-CB 4.31Å; V405-V485 HydrophobicContact CG1-CG2 4.2Å; V405-V485 HydrophobicContact CG2-CB 4.37Å; V405-V485 HydrophobicContact CG2-CG1 4.07Å
406L98Very high95.1Very high8 Ų850.8 Ų50.84%0.04228%0.275CS..EExtended strand (participates in β ladder)trans-122.3151.7163.3-67.1-179.3000109.4H78 L362 H403 R424H78-L406 HydrophobicContact CB-CD1 4Å; L362-L406 HydrophobicContact CD1-CD1 3.58Å; L362-L406 HydrophobicContact CD1-CG 4.33Å; L362-L406 HydrophobicContact CD2-CD1 4.2Å; L362-L406 HydrophobicContact CD2-CG 4.04Å; L362-L406 HydrophobicContact CG-CD1 3.73Å; L362-L406 HydrophobicContact CG-CG 4.04Å; H403-L406 HydrophobicContact CB-CD2 3.92Å; H403-L406 HydrophobicContact CB-CG 4.16Å; L406-R424 HydrophobicContact CB-CB 4.04Å; L406-R424 HydrophobicContact CB-CG 4.38Å; L406-R424 PolarHBondContact N-O 3.16Å; L406-R424 PolarHBondContact O-N 2.82Å
407F98.3Very high95.1Very high32 Ų3253.4 Ų53.414%0.1429%0.286CS..EExtended strand (participates in β ladder)trans-116.4138.6174-59.8-80.7000108.4L96 V405 P409 L420 V423 V485 L486 V489L96-F407 HydrophobicContact CD1-CB 4.49Å; V405-F407 HydrophobicContact CB-CE2 4.5Å; V405-F407 HydrophobicContact CG1-CD2 4.37Å; V405-F407 HydrophobicContact CG1-CE1 3.98Å; V405-F407 HydrophobicContact CG1-CE2 3.66Å; V405-F407 HydrophobicContact CG1-CZ 3.43Å; V405-F407 VanDerWaalsContact CG1-CZ 3.43Å; F407-P409 WeakPolarHBondContact O-CD 3.31Å; F407-L420 HydrophobicContact CB-CD1 4.01Å; F407-L420 HydrophobicContact CB-CD2 4.02Å; F407-L420 HydrophobicContact CB-CG 4.48Å; F407-L420 HydrophobicContact CD1-CD1 4.37Å; F407-L420 HydrophobicContact CG-CD1 4.13Å; F407-V423 HydrophobicContact CD1-CB 4.48Å; F407-V423 HydrophobicContact CD1-CG1 4.24Å; F407-V423 HydrophobicContact CD1-CG2 3.96Å; F407-V423 HydrophobicContact CE1-CB 4.47Å; F407-V423 HydrophobicContact CE1-CG1 3.89Å; F407-V423 HydrophobicContact CE1-CG2 3.95Å; F407-V485 WeakPolarHBondContact CZ-O 3.2Å; F407-L486 HydrophobicContact CE1-CD1 4.41Å; F407-V489 HydrophobicContact CD1-CG1 3.81Å; F407-V489 HydrophobicContact CD2-CB 4.28Å; F407-V489 HydrophobicContact CD2-CG1 4.2Å; F407-V489 HydrophobicContact CD2-CG2 3.89Å; F407-V489 HydrophobicContact CE1-CB 4.05Å; F407-V489 HydrophobicContact CE1-CG1 3.34Å; F407-V489 HydrophobicContact CE2-CB 3.59Å; F407-V489 HydrophobicContact CE2-CG1 3.77Å; F407-V489 HydrophobicContact CE2-CG2 3.58Å; F407-V489 HydrophobicContact CG-CG1 4.22Å; F407-V489 HydrophobicContact CZ-CB 3.46Å; F407-V489 VanDerWaalsContact CZ-CB 3.46Å; F407-V489 HydrophobicContact CZ-CG1 3.31Å; F407-V489 HydrophobicContact CZ-CG2 4Å
408H97.8Very high95.2Very high6 Ų651.7 Ų51.73%0.02827%0.269CS..EExtended strand (participates in β ladder)trans-115.4100.7-179.9-55.2-63.3000108H78 T336 H341 T422 R424H78-H408 AromaticContact ND1-CE1 3.79Å; T336-H408 HydrophobicContact CG2-CB 4.13Å; T336-H408 WeakPolarHBondContact CG2-O 3.27Å; H341-H408 AromaticContact CD2-CG 4Å; H341-H408 AromaticContact CD2-ND1 3.89Å; H341-H408 AromaticContact CE1-CD2 3.76Å; H341-H408 AromaticContact CE1-CE1 3.1Å; H341-H408 PolarHBondContact CE1-CE1 3.25Å; H341-H408 AromaticContact CE1-CG 3.66Å; H341-H408 AromaticContact CE1-ND1 3.26Å; H341-H408 PolarHBondContact CE1-ND1 2.84Å; H341-H408 VanDerWaalsContact CE1-ND1 3.26Å; H341-H408 AromaticContact CE1-NE2 3.42Å; H341-H408 PolarHBondContact CE1-NE2 3.45Å; H341-H408 AromaticContact CG-ND1 3.71Å; H341-H408 AromaticContact ND1-CE1 3.34Å; H341-H408 PolarHBondContact ND1-CE1 3.17Å; H341-H408 VanDerWaalsContact ND1-CE1 3.34Å; H341-H408 AromaticContact ND1-ND1 3.31Å; H341-H408 PolarHBondContact ND1-ND1 3.41Å; H341-H408 AromaticContact NE2-CD2 3.79Å; H341-H408 AromaticContact NE2-CE1 3.81Å; H341-H408 AromaticContact NE2-CG 3.57Å; H341-H408 AromaticContact NE2-ND1 3.59Å; H341-H408 AromaticContact NE2-NE2 3.93Å; H408-T422 HydrophobicContact CB-CG2 4.27Å; H408-T422 PolarHBondContact N-O 2.77Å; H408-T422 VanDerWaalsContact N-O 3.13Å; H408-R424 WeakPolarHBondContact NE2-CB 3.18Å
409P98.1Very high95.4Very high8 Ų844.7 Ų44.75%0.05225%0.247CC..EExtended strand (participates in β ladder)trans-62.1138.4178.8-18.730.6000111.5A80 L96 F407 S411 L420A80-P409 WeakPolarHBondContact O-CD 3.34Å; A80-P409 WeakPolarHBondContact O-CG 3.36Å; L96-P409 HydrophobicContact CD2-CG 3.96Å; F407-P409 WeakPolarHBondContact O-CD 3.31Å; P409-S411 PolarHBondContact O-N 3.48Å; P409-S411 PolarHBondContact O-OG 3.26Å; P409-L420 HydrophobicContact CB-CD2 4Å; P409-L420 HydrophobicContact CG-CD2 3.76Å
410N98.6Very high95.7Very high3 Ų343.3 Ų43.32%0.01624%0.236CC..  trans-56.6134.3172.4-70.6-13.3000110.7A414 G415 E416 G418 A419 Q421N410-A414 VanDerWaalsContact CB-O 3.31Å; N410-A414 WeakPolarHBondContact CB-O 3.3Å; N410-A414 VanDerWaalsContact CG-O 3.27Å; N410-A414 PolarHBondContact ND2-O 2.85Å; N410-G415 WeakPolarHBondContact ND2-CA 3.16Å; N410-E416 WeakPolarHBondContact CB-O 3.3Å; N410-G418 PolarHBondContact O-N 3.07Å; N410-A419 PolarHBondContact N-O 2.75Å; N410-Q421 PolarHBondContact ND2-OE1 2.98Å
411S97.1Very high96.6Very high3 Ų340.3 Ų40.32%0.02122%0.222CC..  trans-128.922.8-165.9-64.20000113S82 T83 Q334 P409 F417S82-S411 PolarHBondContact N-OG 2.95Å; T83-S411 WeakPolarHBondContact CG2-O 3.35Å; Q334-S411 WeakPolarHBondContact CA-O 3.44Å; Q334-S411 WeakPolarHBondContact CB-O 3.39Å; Q334-S411 CarbonylContact O-C 3.56Å; Q334-S411 VanDerWaalsContact O-C 3.24Å; P409-S411 PolarHBondContact O-N 3.48Å; P409-S411 PolarHBondContact O-OG 3.26Å; S411-F417 VanDerWaalsContact C-CE1 3.4Å; S411-F417 WeakPolarHBondContact O-CE1 3.41Å
412G95Very high97.2Very high32 Ų3235.6 Ų35.633%0.3319%0.192SC..SBendtrans114.9-20.5169.800000115.9F417G412-F417 VanDerWaalsContact CA-CZ 3.41Å
413A96.8Very high97.6Very high18 Ų1834.6 Ų34.615%0.14918%0.181CC..SBendtrans-79.4-24.3178.100000114.2Q334 T335 A437Q334-A413 HydrophobicContact CB-CB 4.41Å; Q334-A413 VanDerWaalsContact O-CB 3.23Å; Q334-A413 WeakPolarHBondContact O-CB 3.48Å; Q334-A413 PolarHBondContact O-N 3.25Å; Q334-A413 VanDerWaalsContact O-N 3.07Å; T335-A413 HydrophobicContact CG2-CB 3.67Å; A413-A437 HydrophobicContact CB-CB 4.18Å
414A97.4Very high97.6Very high12 Ų1233.7 Ų33.710%0.09918%0.176CC..SBendtrans-162.3149.1175.900000110.9N410 V433 E447N410-A414 VanDerWaalsContact CB-O 3.31Å; N410-A414 WeakPolarHBondContact CB-O 3.3Å; N410-A414 VanDerWaalsContact CG-O 3.27Å; N410-A414 PolarHBondContact ND2-O 2.85Å; A414-V433 HydrophobicContact CB-CG1 3.66Å; A414-E447 WeakPolarHBondContact CA-OE2 3.49Å; A414-E447 HydrophobicContact CB-CB 4.36Å; A414-E447 HydrophobicContact CB-CG 4.01Å
415G97.4Very high97.7Very high25 Ų2526.1 Ų26.126%0.25815%0.148SC..SBendtrans64.2179.8-179.200000113.7N410 E447N410-G415 WeakPolarHBondContact ND2-CA 3.16Å; G415-E447 PolarHBondContact N-OE2 3Å
416E97.6Very high97.6Very high162 Ų16228.2 Ų28.276%0.75716%0.156SC*.SBendtrans-73.6139.3-179.1-64.5179.3177.600111.4N410 G418 A419N410-E416 WeakPolarHBondContact CB-O 3.3Å; E416-G418 PolarHBondContact O-N 2.73Å; E416-A419 HydrophobicContact CB-CB 4.22Å; E416-A419 VanDerWaalsContact O-CB 3.24Å; E416-A419 WeakPolarHBondContact O-CB 3.27Å; E416-A419 PolarHBondContact O-N 2.82Å
417F97.6Very high97.6Very high94 Ų9432.7 Ų32.741%0.41217%0.172SC..THydrogen-bonded Turntrans-52.7129.8177.5-78.6-78.2000112.1H104 S411 G412 A419H104-F417 HydrophobicContact CB-CB 4.41Å; H104-F417 HydrophobicContact CB-CD1 3.86Å; H104-F417 HydrophobicContact CB-CD2 4.4Å; H104-F417 HydrophobicContact CB-CE1 4.16Å; H104-F417 HydrophobicContact CB-CG 3.99Å; S411-F417 VanDerWaalsContact C-CE1 3.4Å; S411-F417 WeakPolarHBondContact O-CE1 3.41Å; G412-F417 VanDerWaalsContact CA-CZ 3.41Å; F417-A419 PolarHBondContact O-N 2.84Å
418G97.4Very high97.6Very high2 Ų232.1 Ų32.12%0.02117%0.169CC..THydrogen-bonded Turntrans82.2-16.7-179.300000114.7L98 N410 E416 L420L98-G418 VanDerWaalsContact CD1-O 3.3Å; L98-G418 WeakPolarHBondContact CD1-O 3.33Å; L98-G418 WeakPolarHBondContact CD2-O 3.44Å; L98-G418 WeakPolarHBondContact CG-O 3.29Å; N410-G418 PolarHBondContact O-N 3.07Å; E416-G418 PolarHBondContact O-N 2.73Å; G418-L420 PolarHBondContact O-N 3.23Å
419A98.1Very high97.7Very high21 Ų2131.8 Ų31.817%0.17417%0.168CC..  trans-61.9139.2-179.300000111.7N410 E416 F417 Q421N410-A419 PolarHBondContact N-O 2.75Å; E416-A419 HydrophobicContact CB-CB 4.22Å; E416-A419 VanDerWaalsContact O-CB 3.24Å; E416-A419 WeakPolarHBondContact O-CB 3.27Å; E416-A419 PolarHBondContact O-N 2.82Å; F417-A419 PolarHBondContact O-N 2.84Å; A419-Q421 PolarHBondContact O-N 3.44Å
420L98.1Very high97.7Very high7 Ų731.4 Ų31.44%0.03717%0.165CC..EExtended strand (participates in β ladder)trans-92.796.5178.9-55.8-173.5000109.7L96 L98 F407 P409 G418 L486 V489 L490 I493L96-L420 HydrophobicContact CD1-CD1 4.41Å; L98-L420 HydrophobicContact CD1-CD1 4.33Å; L98-L420 HydrophobicContact CD1-CD2 4.4Å; L98-L420 HydrophobicContact CD1-CG 3.81Å; F407-L420 HydrophobicContact CB-CD1 4.01Å; F407-L420 HydrophobicContact CB-CD2 4.02Å; F407-L420 HydrophobicContact CB-CG 4.48Å; F407-L420 HydrophobicContact CD1-CD1 4.37Å; F407-L420 HydrophobicContact CG-CD1 4.13Å; P409-L420 HydrophobicContact CB-CD2 4Å; P409-L420 HydrophobicContact CG-CD2 3.76Å; G418-L420 PolarHBondContact O-N 3.23Å; L420-L486 HydrophobicContact CB-CD1 4.19Å; L420-L486 WeakPolarHBondContact O-CD1 3.21Å; L420-V489 HydrophobicContact CD1-CG1 3.9Å; L420-V489 HydrophobicContact CD1-CG2 4.27Å; L420-L490 HydrophobicContact CB-CD2 4.3Å; L420-I493 HydrophobicContact CD1-CD1 3.69Å
421Q97.9Very high97.7Very high58 Ų5831.3 Ų31.327%0.27117%0.165SC..EExtended strand (participates in β ladder)trans-125.53177.4-66.3178-58.200112.7N410 A419 Y432 V433N410-Q421 PolarHBondContact ND2-OE1 2.98Å; A419-Q421 PolarHBondContact O-N 3.44Å; Q421-Y432 PolarHBondContact O-N 3.13Å; Q421-V433 HydrophobicContact CB-CB 4.37Å; Q421-V433 HydrophobicContact CB-CG2 4.31Å; Q421-V433 HydrophobicContact CG-CG2 4.45Å
422T98.5Very high97.8Very high0 Ų033 Ų330%017%0.171CC..EExtended strand (participates in β ladder)trans-125.6127.8173.7-53.80000109.9T336 H408 K429 A430 F431T336-T422 WeakPolarHBondContact CB-OG1 3.31Å; T336-T422 PolarHBondContact OG1-OG1 3Å; H408-T422 HydrophobicContact CB-CG2 4.27Å; H408-T422 PolarHBondContact N-O 2.77Å; H408-T422 VanDerWaalsContact N-O 3.13Å; T422-K429 HydrophobicContact CG2-CG 4.32Å; T422-A430 CarbonylContact C-O 3.47Å; T422-A430 VanDerWaalsContact CA-O 3.28Å; T422-A430 WeakPolarHBondContact CA-O 3.41Å; T422-F431 HydrophobicContact CG2-CD1 3.66Å; T422-F431 HydrophobicContact CG2-CE1 3.58Å; T422-F431 HydrophobicContact CG2-CE2 4.49Å; T422-F431 HydrophobicContact CG2-CG 4.19Å; T422-F431 HydrophobicContact CG2-CZ 4.03Å
423V98.4Very high97.9Very high0 Ų031.6 Ų31.60%016%0.156CC..EExtended strand (participates in β ladder)trans-126.7127-175-1760000109.8V405 F407 K429 A430 V482 V485 L486V405-V423 HydrophobicContact CG1-CG1 4.03Å; F407-V423 HydrophobicContact CD1-CB 4.48Å; F407-V423 HydrophobicContact CD1-CG1 4.24Å; F407-V423 HydrophobicContact CD1-CG2 3.96Å; F407-V423 HydrophobicContact CE1-CB 4.47Å; F407-V423 HydrophobicContact CE1-CG1 3.89Å; F407-V423 HydrophobicContact CE1-CG2 3.95Å; V423-K429 CarbonylContact O-C 3.6Å; V423-K429 WeakPolarHBondContact O-CA 3.19Å; V423-A430 PolarHBondContact N-O 3.16Å; V423-A430 PolarHBondContact O-N 2.94Å; V423-V482 HydrophobicContact CB-CG1 4.47Å; V423-V485 HydrophobicContact CG1-CG2 3.77Å; V423-L486 HydrophobicContact CG2-CB 4.09Å; V423-L486 HydrophobicContact CG2-CD1 4Å; V423-L486 HydrophobicContact CG2-CD2 4.4Å; V423-L486 HydrophobicContact CG2-CG 4.39Å
424R98.3Very high98Very high13 Ų1330.8 Ų30.85%0.04915%0.149CC..EExtended strand (participates in β ladder)trans-96.3113.3164.5173.567.3166.8164.42.5107.7D76 L362 V405 L406 H408 E426 R427 Y428 L458D76-R424 IonicContact OD2-NH2 2.73Å; L362-R424 HydrophobicContact CD1-CG 4.32Å; L362-R424 HydrophobicContact CD2-CG 3.93Å; V405-R424 CarbonylContact C-O 3.49Å; V405-R424 WeakPolarHBondContact CA-O 3.38Å; V405-R424 WeakPolarHBondContact CG1-O 3.41Å; L406-R424 HydrophobicContact CB-CB 4.04Å; L406-R424 HydrophobicContact CB-CG 4.38Å; L406-R424 PolarHBondContact N-O 3.16Å; L406-R424 PolarHBondContact O-N 2.82Å; H408-R424 WeakPolarHBondContact NE2-CB 3.18Å; R424-E426 WeakPolarHBondContact CD-O 3.43Å; R424-E426 PolarHBondContact NE-O 2.73Å; R424-E426 PolarHBondContact NH1-O 2.81Å; R424-E426 PolarHBondContact NH2-O 2.99Å; R424-R427 VanDerWaalsContact NH1-CA 3.33Å; R424-R427 PolarHBondContact NH1-O 2.94Å; R424-Y428 CarbonylContact C-O 3.59Å; R424-Y428 WeakPolarHBondContact CA-O 3.44Å; R424-L458 VanDerWaalsContact NH1-CB 3.32Å
425L98.3Very high98Very high9 Ų930.4 Ų30.45%0.04715%0.146CC..EExtended strand (participates in β ladder)trans-117.2106.4173.7170.463.7000108.3V405 R427 Y428 K481 V482 V485V405-L425 HydrophobicContact CG2-CD1 3.68Å; L425-R427 PolarHBondContact O-N 3.03Å; L425-Y428 PolarHBondContact N-O 3.1Å; L425-Y428 WeakPolarHBondContact O-CA 3.4Å; L425-Y428 WeakPolarHBondContact O-CB 3.35Å; L425-Y428 PolarHBondContact O-N 3.01Å; L425-K481 HydrophobicContact CD2-CB 3.57Å; L425-V482 HydrophobicContact CB-CG2 4.49Å; L425-V482 HydrophobicContact CD2-CG2 4.06Å; L425-V485 HydrophobicContact CD1-CG1 4.36Å
426E96Very high98.1Very high79 Ų7929.2 Ų29.237%0.36913%0.134SC..THydrogen-bonded Turntrans51.8-121.1-173.7-60.5168.617700109.2R404 R424 Y428R404-E426 IonicContact CZ-OE1 3.99Å; R404-E426 IonicContact NE-OE1 2.72Å; R404-E426 PolarHBondContact NE-OE1 2.79Å; R404-E426 VanDerWaalsContact NE-OE1 3.16Å; R404-E426 IonicContact NH2-OE1 3.01Å; R404-E426 PolarHBondContact NH2-OE1 3.36Å; R404-E426 PolarHBondContact O-N 2.79Å; R424-E426 WeakPolarHBondContact CD-O 3.43Å; R424-E426 PolarHBondContact NE-O 2.73Å; R424-E426 PolarHBondContact NH1-O 2.81Å; R424-E426 PolarHBondContact NH2-O 2.99Å; E426-Y428 VanDerWaalsContact C-N 3.35Å
427R97Very high98.1Very high103 Ų10321.8 Ų21.839%0.38910%0.1SC..THydrogen-bonded Turntrans-82.4-5.9176.366.8-173168.4-160.3-1.4115.1R424 L425 L458 E459R424-R427 VanDerWaalsContact NH1-CA 3.33Å; R424-R427 PolarHBondContact NH1-O 2.94Å; L425-R427 PolarHBondContact O-N 3.03Å; R427-L458 PolarHBondContact O-N 3.24Å; R427-E459 HydrophobicContact CB-CB 4.17Å; R427-E459 WeakPolarHBondContact CD-OE2 3.46Å; R427-E459 IonicContact CZ-OE2 3.7Å; R427-E459 IonicContact NE-OE2 3.61Å; R427-E459 IonicContact NH1-OE2 2.72Å; R427-E459 PolarHBondContact NH1-OE2 2.96Å
428Y98.7Very high98.1Very high19 Ų1922.4 Ų22.48%0.07510%0.1CC..EExtended strand (participates in β ladder)trans-95.9136.9-177.6-60.2-73000111.3R424 L425 E426 I455 F456 N457 L468 E474 V478R424-Y428 CarbonylContact C-O 3.59Å; R424-Y428 WeakPolarHBondContact CA-O 3.44Å; L425-Y428 PolarHBondContact N-O 3.1Å; L425-Y428 WeakPolarHBondContact O-CA 3.4Å; L425-Y428 WeakPolarHBondContact O-CB 3.35Å; L425-Y428 PolarHBondContact O-N 3.01Å; E426-Y428 VanDerWaalsContact C-N 3.35Å; Y428-I455 HydrophobicContact CD1-CG2 4.13Å; Y428-I455 HydrophobicContact CG-CG2 4.49Å; Y428-F456 CarbonylContact C-O 3.58Å; Y428-F456 VanDerWaalsContact CA-O 3.29Å; Y428-F456 WeakPolarHBondContact CA-O 3.44Å; Y428-N457 HydrophobicContact CD1-CB 4.09Å; Y428-N457 HydrophobicContact CE1-CB 3.87Å; Y428-L468 HydrophobicContact CD1-CD1 4.13Å; Y428-L468 HydrophobicContact CE1-CD1 4.05Å; Y428-E474 HydrophobicContact CE1-CG 4.05Å; Y428-E474 WeakPolarHBondContact CE1-OE1 3.48Å; Y428-E474 VanDerWaalsContact CZ-OE1 3.25Å; Y428-E474 PolarHBondContact OH-OE1 3.18Å; Y428-V478 HydrophobicContact CD1-CG1 4.26Å; Y428-V478 HydrophobicContact CD1-CG2 4.12Å; Y428-V478 HydrophobicContact CD2-CG1 3.93Å; Y428-V478 HydrophobicContact CD2-CG2 3.75Å; Y428-V478 HydrophobicContact CE1-CG2 3.97Å; Y428-V478 HydrophobicContact CE2-CG2 3.58Å; Y428-V478 HydrophobicContact CG-CG1 3.73Å; Y428-V478 HydrophobicContact CG-CG2 4.02Å
429K98.8Very high98Very high0 Ų023 Ų230%011%0.105CC..EExtended strand (participates in β ladder)trans-123.6123.2173.5-169.5173.4171.6-1630110.3T336 W337 E338 H341 T422 V423 F431 I455 F456 L458 E464T336-K429 WeakPolarHBondContact O-CE 3.38Å; T336-K429 PolarHBondContact O-NZ 2.76Å; W337-K429 VanDerWaalsContact C-NZ 3.31Å; E338-K429 HydrophobicContact CG-CD 4.46Å; E338-K429 WeakPolarHBondContact OE1-CD 3.28Å; E338-K429 WeakPolarHBondContact OE1-CE 3.36Å; E338-K429 IonicContact OE1-NZ 2.62Å; E338-K429 PolarHBondContact OE1-NZ 3.36Å; H341-K429 PolarHBondContact NE2-NZ 3.31Å; T422-K429 HydrophobicContact CG2-CG 4.32Å; V423-K429 CarbonylContact O-C 3.6Å; V423-K429 WeakPolarHBondContact O-CA 3.19Å; K429-F431 HydrophobicContact CD-CE2 4.02Å; K429-F431 HydrophobicContact CD-CZ 4Å; K429-F431 HydrophobicContact CG-CE2 3.83Å; K429-F431 HydrophobicContact CG-CZ 4.2Å; K429-I455 CarbonylContact O-C 3.52Å; K429-I455 WeakPolarHBondContact O-CA 3.37Å; K429-F456 PolarHBondContact N-O 3.48Å; K429-F456 PolarHBondContact O-N 2.75Å; K429-L458 HydrophobicContact CB-CD1 4.09Å; K429-L458 HydrophobicContact CB-CD2 4.34Å; K429-L458 HydrophobicContact CB-CG 4.15Å; K429-L458 HydrophobicContact CD-CD1 4.01Å; K429-E464 WeakPolarHBondContact CD-OE1 3.33Å; K429-E464 WeakPolarHBondContact CE-OE1 3.21Å; K429-E464 IonicContact NZ-OE1 3.66Å; K429-E464 PolarHBondContact NZ-OE1 3.18Å; K429-E464 IonicContact NZ-OE2 3.58Å
430A98.8Very high97.9Very high0 Ų025 Ų250%012%0.117CC..EExtended strand (participates in β ladder)trans-118132-170.800000111.8T422 V423 P453 L454 I455 V482T422-A430 CarbonylContact C-O 3.47Å; T422-A430 VanDerWaalsContact CA-O 3.28Å; T422-A430 WeakPolarHBondContact CA-O 3.41Å; V423-A430 PolarHBondContact N-O 3.16Å; V423-A430 PolarHBondContact O-N 2.94Å; A430-P453 HydrophobicContact CB-CB 4.25Å; A430-L454 CarbonylContact C-O 3.59Å; A430-L454 WeakPolarHBondContact CA-O 3.41Å; A430-I455 HydrophobicContact CB-CG1 3.96Å; A430-V482 HydrophobicContact CB-CB 4.43Å; A430-V482 HydrophobicContact CB-CG1 3.5Å; A430-V482 VanDerWaalsContact CB-CG1 3.5Å; A430-V482 HydrophobicContact CB-CG2 4.08Å
431F98.8Very high97.7Very high0 Ų030.7 Ų30.70%015%0.147CC..EExtended strand (participates in β ladder)trans-119.1116-178.3-64.8-98.4000110.8T336 W337 T422 K429 T434 P453 L454 F456 E464T336-F431 WeakPolarHBondContact OG1-CE1 3.46Å; W337-F431 HydrophobicContact CD2-CE1 4.06Å; W337-F431 HydrophobicContact CD2-CZ 4.01Å; W337-F431 HydrophobicContact CE3-CE1 4.04Å; W337-F431 HydrophobicContact CE3-CE2 4.11Å; W337-F431 AromaticContact CE3-CZ 3.54Å; W337-F431 HydrophobicContact CE3-CZ 3.54Å; W337-F431 HydrophobicContact CH2-CZ 4.39Å; W337-F431 HydrophobicContact CZ3-CD2 4.48Å; W337-F431 HydrophobicContact CZ3-CE1 4.28Å; W337-F431 AromaticContact CZ3-CE2 3.89Å; W337-F431 HydrophobicContact CZ3-CE2 3.89Å; W337-F431 AromaticContact CZ3-CZ 3.75Å; W337-F431 HydrophobicContact CZ3-CZ 3.75Å; T422-F431 HydrophobicContact CG2-CD1 3.66Å; T422-F431 HydrophobicContact CG2-CE1 3.58Å; T422-F431 HydrophobicContact CG2-CE2 4.49Å; T422-F431 HydrophobicContact CG2-CG 4.19Å; T422-F431 HydrophobicContact CG2-CZ 4.03Å; K429-F431 HydrophobicContact CD-CE2 4.02Å; K429-F431 HydrophobicContact CD-CZ 4Å; K429-F431 HydrophobicContact CG-CE2 3.83Å; K429-F431 HydrophobicContact CG-CZ 4.2Å; F431-T434 HydrophobicContact CB-CG2 3.65Å; F431-T434 HydrophobicContact CD1-CG2 4.05Å; F431-T434 HydrophobicContact CG-CG2 3.99Å; F431-P453 CarbonylContact O-C 3.52Å; F431-P453 WeakPolarHBondContact O-CA 3.46Å; F431-P453 VanDerWaalsContact O-CB 3.29Å; F431-P453 WeakPolarHBondContact O-CB 3.16Å; F431-L454 HydrophobicContact CB-CB 4.46Å; F431-L454 PolarHBondContact N-O 2.82Å; F431-L454 PolarHBondContact O-N 3.38Å; F431-F456 AromaticContact CD2-CD2 3.82Å; F431-F456 HydrophobicContact CD2-CD2 3.82Å; F431-F456 AromaticContact CD2-CE2 3.74Å; F431-F456 HydrophobicContact CD2-CE2 3.74Å; F431-F456 AromaticContact CE2-CD2 3.73Å; F431-F456 HydrophobicContact CE2-CD2 3.73Å; F431-F456 AromaticContact CE2-CE2 3.85Å; F431-F456 HydrophobicContact CE2-CE2 3.85Å; F431-E464 VanDerWaalsContact CZ-OE1 3.27Å; F431-E464 WeakPolarHBondContact CZ-OE1 3.39Å
432Y98.6Very high97.5Very high39 Ų3929.6 Ų29.615%0.15315%0.152CC..EExtended strand (participates in β ladder)trans-84.3-24.2167.6-74.3-86.8000112.3Q421 H450 P453 V482 R483 L486Q421-Y432 PolarHBondContact O-N 3.13Å; Y432-H450 PolarHBondContact O-N 3.06Å; Y432-P453 HydrophobicContact CD1-CB 4.13Å; Y432-P453 HydrophobicContact CD1-CG 4.48Å; Y432-P453 HydrophobicContact CD2-CB 4.1Å; Y432-P453 HydrophobicContact CE1-CB 4.08Å; Y432-P453 HydrophobicContact CE1-CG 3.93Å; Y432-P453 HydrophobicContact CE2-CB 4.03Å; Y432-P453 HydrophobicContact CE2-CG 4.11Å; Y432-P453 HydrophobicContact CG-CB 4.15Å; Y432-V482 HydrophobicContact CE2-CG1 4.27Å; Y432-R483 VanDerWaalsContact OH-CG 3.22Å; Y432-R483 WeakPolarHBondContact OH-CG 3.04Å; Y432-L486 HydrophobicContact CD2-CD2 3.78Å; Y432-L486 HydrophobicContact CE2-CD2 3.48Å; Y432-L486 VanDerWaalsContact CE2-CD2 3.48Å
433V98.4Very high97.4Very high3 Ų331.4 Ų31.42%0.01816%0.164CC..EExtended strand (participates in β ladder)trans-134.9139173.4178.60000107.7A414 Q421 E447 L448 Q449A414-V433 HydrophobicContact CB-CG1 3.66Å; Q421-V433 HydrophobicContact CB-CB 4.37Å; Q421-V433 HydrophobicContact CB-CG2 4.31Å; Q421-V433 HydrophobicContact CG-CG2 4.45Å; V433-E447 HydrophobicContact CG1-CG 3.92Å; V433-L448 WeakPolarHBondContact CA-O 3.38Å; V433-Q449 HydrophobicContact CG2-CG 4.26Å
434T98.4Very high97.4Very high0 Ų035.9 Ų35.90%019%0.187CC..EExtended strand (participates in β ladder)trans-128.2146.3174.253.20000110W323 W337 F431 E447 L448 H450 L454W323-T434 HydrophobicContact CH2-CG2 4.43Å; W323-T434 HydrophobicContact CZ3-CG2 4.06Å; W337-T434 HydrophobicContact CH2-CG2 3.88Å; W337-T434 HydrophobicContact CZ2-CG2 3.63Å; F431-T434 HydrophobicContact CB-CG2 3.65Å; F431-T434 HydrophobicContact CD1-CG2 4.05Å; F431-T434 HydrophobicContact CG-CG2 3.99Å; T434-E447 CarbonylContact O-C 3.55Å; T434-E447 VanDerWaalsContact O-CA 3.31Å; T434-E447 WeakPolarHBondContact O-CA 3.43Å; T434-L448 PolarHBondContact N-O 3.07Å; T434-L448 PolarHBondContact O-N 3.04Å; T434-H450 PolarHBondContact OG1-NE2 3.23Å; T434-L454 HydrophobicContact CG2-CD1 4.03Å
435G98Very high97.3Very high4 Ų435.3 Ų35.34%0.04119%0.185CC..EExtended strand (participates in β ladder)trans-165.5167.2166.200000110.1Q324 W337Q324-G435 VanDerWaalsContact CD-C 3.45Å; Q324-G435 VanDerWaalsContact OE1-C 3.27Å; Q324-G435 PolarHBondContact OE1-O 3.01Å; W337-G435 PolarHBondContact NE1-O 2.72Å
436G97.8Very high97.2Very high0 Ų037.8 Ų37.80%020%0.202CC..EExtended strand (participates in β ladder)trans-117.9134-179.600000110.1S330 I444 G445S330-G436 CarbonylContact O-C 3.6Å; S330-G436 WeakPolarHBondContact O-CA 3.18Å; G436-I444 WeakPolarHBondContact O-CG2 3.06Å; G436-G445 PolarHBondContact N-O 3.49Å; G436-G445 PolarHBondContact O-N 2.72Å
437A97.9Very high97.3Very high6 Ų638.6 Ų38.65%0.0521%0.206CC..BIsolated β-bridgetrans-63.8168.3174.100000110.7G329 S330 K333 Q334 T335 A413 A439G329-A437 CarbonylContact C-O 3.29Å; G329-A437 WeakPolarHBondContact CA-O 3.39Å; S330-A437 PolarHBondContact N-O 2.96Å; S330-A437 PolarHBondContact O-N 3.42Å; K333-A437 WeakPolarHBondContact O-CB 3.35Å; Q334-A437 HydrophobicContact CB-CB 4.11Å; T335-A437 HydrophobicContact CG2-CB 3.74Å; A413-A437 HydrophobicContact CB-CB 4.18Å; A437-A439 PolarHBondContact O-N 3.12Å
438R97.3Very high97.4Very high108 Ų10836.8 Ų36.841%0.40820%0.203SC..PPolyproline II helixtrans-61.1127.3174.6-168.9-178.1-62.9-837.9110.3E308 G442 S443 I444E308-R438 HydrophobicContact CG-CB 4.39Å; E308-R438 HydrophobicContact CG-CG 4.21Å; E308-R438 WeakPolarHBondContact OE1-CD 3.41Å; E308-R438 IonicContact OE1-NE 3.79Å; R438-G442 PolarHBondContact NH1-O 3.07Å; R438-S443 CarbonylContact C-O 3.34Å; R438-S443 WeakPolarHBondContact CA-O 3.23Å; R438-I444 HydrophobicContact CB-CG1 4.15Å; R438-I444 HydrophobicContact CG-CG1 4.21Å
439A96.6Very high97.4Very high15 Ų1543.1 Ų43.112%0.12423%0.233CC..PPolyproline II helixtrans-90.6169.7173.700000111.5A437 D441 G442 S443A437-A439 PolarHBondContact O-N 3.12Å; A439-D441 WeakPolarHBondContact CB-OD1 3.29Å; A439-D441 PolarHBondContact O-N 3.17Å; A439-G442 WeakPolarHBondContact O-CA 3.1Å; A439-G442 PolarHBondContact O-N 3.29Å; A439-S443 PolarHBondContact N-O 2.87Å
440C94.6Very high97.3Very high63 Ų6344.4 Ų44.443%0.42624%0.239SC..THydrogen-bonded Turntrans-54.9-34.8177.9170.70000113.8A307 C310 G442A307-C440 PolarHBondContact O-N 2.89Å; C310-C440 VanDerWaalsContact CA-SG 3.53Å; C310-C440 HydrophobicContact CB-CB 3.89Å; C310-C440 WeakPolarHBondContact CB-SG 3.29Å; C310-C440 VanDerWaalsContact SG-CA 3.52Å; C310-C440 WeakPolarHBondContact SG-CB 3.33Å; C310-C440 CovalentContact SG-SG 2.02Å; C310-C440 PolarHBondContact SG-SG 3.4Å; C440-G442 PolarHBondContact O-N 2.86Å
441D94.3Very high97.2Very high126 Ų12653.9 Ų53.967%0.67428%0.281SS*.THydrogen-bonded Turntrans-77.35177.167.2-2.5000113.4A439 S443A439-D441 WeakPolarHBondContact CB-OD1 3.29Å; A439-D441 PolarHBondContact O-N 3.17Å; D441-S443 PolarHBondContact O-N 2.96Å; D441-S443 WeakPolarHBondContact OD1-CB 3.03Å; D441-S443 PolarHBondContact OD1-N 3.41Å; D441-S443 PolarHBondContact OD1-OG 2.73Å
442G94.1Very high97.1Very high35 Ų3556.3 Ų56.336%0.36129%0.293SS..SBendtrans80.2-5.5-177.700000114.4R438 A439 C440R438-G442 PolarHBondContact NH1-O 3.07Å; A439-G442 WeakPolarHBondContact O-CA 3.1Å; A439-G442 PolarHBondContact O-N 3.29Å; C440-G442 PolarHBondContact O-N 2.86Å
443S96.4Very high97.1Very high38 Ų3854.5 Ų54.527%0.26629%0.286SS..  trans-66.2147.2178.371.20000111.3G329 R438 A439 D441G329-S443 PolarHBondContact N-OG 3.33Å; G329-S443 VanDerWaalsContact N-OG 3.13Å; R438-S443 CarbonylContact C-O 3.34Å; R438-S443 WeakPolarHBondContact CA-O 3.23Å; A439-S443 PolarHBondContact N-O 2.87Å; D441-S443 PolarHBondContact O-N 2.96Å; D441-S443 WeakPolarHBondContact OD1-CB 3.03Å; D441-S443 PolarHBondContact OD1-N 3.41Å; D441-S443 PolarHBondContact OD1-OG 2.73Å
444I97.4Very high97.1Very high94 Ų9455 Ų5548%0.48229%0.289SS..  trans-123.4136.6174.8-59.1177.4000107G436 R438G436-I444 WeakPolarHBondContact O-CG2 3.06Å; R438-I444 HydrophobicContact CB-CG1 4.15Å; R438-I444 HydrophobicContact CG-CG1 4.21Å
445G97.1Very high97.1Very high1 Ų155 Ų551%0.0129%0.289CS..EExtended strand (participates in β ladder)trans-78.4128176.200000109.8Q324 G328 G436 E447Q324-G445 VanDerWaalsContact NE2-CA 3.33Å; G328-G445 VanDerWaalsContact C-CA 3.48Å; G328-G445 WeakPolarHBondContact O-CA 3.4Å; G328-G445 PolarHBondContact O-N 3.28Å; G436-G445 PolarHBondContact N-O 3.49Å; G436-G445 PolarHBondContact O-N 2.72Å; G445-E447 PolarHBondContact O-N 3.25Å
446P97.3Very high97.1Very high60 Ų6054.9 Ų54.939%0.3929%0.287SS..EExtended strand (participates in β ladder)trans-62.8140.7-175.927-34.5000110.8R327 L448R327-P446 WeakPolarHBondContact O-CD 3.37Å; P446-L448 PolarHBondContact O-N 3.5Å
447E97.9Very high97.2Very high97 Ų9755.2 Ų55.245%0.45329%0.289SS..EExtended strand (participates in β ladder)trans-66128.8166.3179.1175.6123.500109.5A414 G415 V433 T434 G445A414-E447 WeakPolarHBondContact CA-OE2 3.49Å; A414-E447 HydrophobicContact CB-CB 4.36Å; A414-E447 HydrophobicContact CB-CG 4.01Å; G415-E447 PolarHBondContact N-OE2 3Å; V433-E447 HydrophobicContact CG1-CG 3.92Å; T434-E447 CarbonylContact O-C 3.55Å; T434-E447 VanDerWaalsContact O-CA 3.31Å; T434-E447 WeakPolarHBondContact O-CA 3.43Å; G445-E447 PolarHBondContact O-N 3.25Å
448L98.1Very high97.2Very high65 Ų6555.2 Ų55.234%0.3429%0.288SS..EExtended strand (participates in β ladder)trans-130.2124.3176.5-57.9171.3000109.2W323 V433 T434 P446 H450W323-L448 HydrophobicContact CH2-CD1 3.8Å; W323-L448 HydrophobicContact CZ3-CD1 4.47Å; V433-L448 WeakPolarHBondContact CA-O 3.38Å; T434-L448 PolarHBondContact N-O 3.07Å; T434-L448 PolarHBondContact O-N 3.04Å; P446-L448 PolarHBondContact O-N 3.5Å; L448-H450 PolarHBondContact O-CD2 3.44Å; L448-H450 PolarHBondContact O-NE2 2.81Å
449Q98Very high97.1Very high151 Ų15156.1 Ų56.171%0.70630%0.297SS*.EExtended strand (participates in β ladder)trans-92.6137.3173.8-59.7-172800110.7V433V433-Q449 HydrophobicContact CG2-CG 4.26Å
450H97.8Very high97.1Very high27 Ų2761.7 Ų61.713%0.12533%0.325CS..EExtended strand (participates in β ladder)trans-118.2112.9-174.7-57.9-74.8000110.9Y432 T434 L448 L452Y432-H450 PolarHBondContact O-N 3.06Å; T434-H450 PolarHBondContact OG1-NE2 3.23Å; L448-H450 PolarHBondContact O-CD2 3.44Å; L448-H450 PolarHBondContact O-NE2 2.81Å; H450-L452 WeakPolarHBondContact CB-O 3.35Å; H450-L452 PolarHBondContact O-N 3.4Å
451K95.6Very high97.2Very high200 Ų20060.1 Ų60.187%0.8731%0.312SS*.EExtended strand (participates in β ladder)trans-56.2-38.5174.1-178.6179.2179.6179.20112.4
452L97.3Very high97.3Very high51 Ų5157.8 Ų57.827%0.26730%0.299SS..EExtended strand (participates in β ladder)trans-119.4129.4168.6-65.6-177.2000107.3H450 R470 Y475 L479H450-L452 WeakPolarHBondContact CB-O 3.35Å; H450-L452 PolarHBondContact O-N 3.4Å; L452-R470 PolarHBondContact O-NH2 3.33Å; L452-Y475 WeakPolarHBondContact CB-OH 3.48Å; L452-L479 HydrophobicContact CD2-CD2 4.16Å
453P98.4Very high97.5Very high0 Ų057.1 Ų57.10%029%0.29CS..EExtended strand (participates in β ladder)trans-63148.8-170.728.4-35.3000110.9A430 F431 Y432 I455 Y475 L479A430-P453 HydrophobicContact CB-CB 4.25Å; F431-P453 CarbonylContact O-C 3.52Å; F431-P453 WeakPolarHBondContact O-CA 3.46Å; F431-P453 VanDerWaalsContact O-CB 3.29Å; F431-P453 WeakPolarHBondContact O-CB 3.16Å; Y432-P453 HydrophobicContact CD1-CB 4.13Å; Y432-P453 HydrophobicContact CD1-CG 4.48Å; Y432-P453 HydrophobicContact CD2-CB 4.1Å; Y432-P453 HydrophobicContact CE1-CB 4.08Å; Y432-P453 HydrophobicContact CE1-CG 3.93Å; Y432-P453 HydrophobicContact CE2-CB 4.03Å; Y432-P453 HydrophobicContact CE2-CG 4.11Å; Y432-P453 HydrophobicContact CG-CB 4.15Å; P453-I455 HydrophobicContact CG-CD1 4.38Å; P453-I455 HydrophobicContact CG-CG1 4.23Å; P453-Y475 WeakPolarHBondContact O-CE2 3.25Å; P453-Y475 PolarHBondContact O-OH 2.9Å; P453-L479 HydrophobicContact CG-CD1 3.62Å
454L98.7Very high97.6Very high15 Ų1555.3 Ų55.38%0.07928%0.277CS..EExtended strand (participates in β ladder)trans-69132.7160.1-56.9-177.2000107.3W323 A430 F431 T434 F456 P467W323-L454 HydrophobicContact CD2-CD1 4.2Å; W323-L454 HydrophobicContact CE3-CD1 4.45Å; W323-L454 HydrophobicContact CH2-CD1 3.66Å; W323-L454 HydrophobicContact CZ2-CD1 3.33Å; W323-L454 HydrophobicContact CZ3-CD1 4.21Å; A430-L454 CarbonylContact C-O 3.59Å; A430-L454 WeakPolarHBondContact CA-O 3.41Å; F431-L454 HydrophobicContact CB-CB 4.46Å; F431-L454 PolarHBondContact N-O 2.82Å; F431-L454 PolarHBondContact O-N 3.38Å; T434-L454 HydrophobicContact CG2-CD1 4.03Å; L454-F456 HydrophobicContact CB-CE2 3.92Å; L454-F456 HydrophobicContact CB-CZ 4.49Å; L454-P467 HydrophobicContact CB-CB 4.17Å; L454-P467 HydrophobicContact CD2-CB 4.4Å; L454-P467 HydrophobicContact CD2-CG 4.34Å
455I98.8Very high97.6Very high0 Ų051.9 Ų51.90%026%0.263CS..EExtended strand (participates in β ladder)trans-122.7126178.1-57.3179.3000107.5Y428 K429 A430 P453 P467 L468 Y475 V478 L479Y428-I455 HydrophobicContact CD1-CG2 4.13Å; Y428-I455 HydrophobicContact CG-CG2 4.49Å; K429-I455 CarbonylContact O-C 3.52Å; K429-I455 WeakPolarHBondContact O-CA 3.37Å; A430-I455 HydrophobicContact CB-CG1 3.96Å; P453-I455 HydrophobicContact CG-CD1 4.38Å; P453-I455 HydrophobicContact CG-CG1 4.23Å; I455-P467 CarbonylContact O-C 3.51Å; I455-P467 VanDerWaalsContact O-CA 3.32Å; I455-P467 WeakPolarHBondContact O-CA 3.43Å; I455-L468 HydrophobicContact CB-CD1 4.32Å; I455-L468 HydrophobicContact CG2-CD1 3.87Å; I455-L468 WeakPolarHBondContact O-CB 3.3Å; I455-L468 WeakPolarHBondContact O-CG 2.97Å; I455-L468 PolarHBondContact O-N 3.08Å; I455-Y475 HydrophobicContact CB-CD2 4.12Å; I455-Y475 HydrophobicContact CB-CE2 4.05Å; I455-Y475 HydrophobicContact CD1-CD2 3.83Å; I455-Y475 HydrophobicContact CD1-CE2 3.55Å; I455-Y475 HydrophobicContact CG1-CD2 4.11Å; I455-Y475 HydrophobicContact CG1-CE2 3.64Å; I455-V478 HydrophobicContact CD1-CG1 4.27Å; I455-V478 HydrophobicContact CG2-CG1 4.21Å; I455-L479 HydrophobicContact CD1-CB 4.36Å; I455-L479 HydrophobicContact CD1-CD1 4.46Å
456F98.8Very high97.6Very high0 Ų056.3 Ų56.30%029%0.29CS..EExtended strand (participates in β ladder)trans-109.3144.4174.8-60.5-95.1000109.2W323 W337 Y428 K429 F431 L454 L458 E464 P467W323-F456 HydrophobicContact CB-CE1 4.11Å; W323-F456 HydrophobicContact CB-CZ 4.01Å; W323-F456 HydrophobicContact CG-CE1 4.37Å; W323-F456 AromaticContact CG-CZ 3.98Å; W323-F456 HydrophobicContact CG-CZ 3.98Å; W337-F456 HydrophobicContact CH2-CE2 4.22Å; W337-F456 HydrophobicContact CH2-CZ 4.19Å; W337-F456 AromaticContact CZ3-CE2 3.9Å; W337-F456 HydrophobicContact CZ3-CE2 3.9Å; W337-F456 AromaticContact CZ3-CZ 3.94Å; W337-F456 HydrophobicContact CZ3-CZ 3.94Å; Y428-F456 CarbonylContact C-O 3.58Å; Y428-F456 VanDerWaalsContact CA-O 3.29Å; Y428-F456 WeakPolarHBondContact CA-O 3.44Å; K429-F456 PolarHBondContact N-O 3.48Å; K429-F456 PolarHBondContact O-N 2.75Å; F431-F456 AromaticContact CD2-CD2 3.82Å; F431-F456 HydrophobicContact CD2-CD2 3.82Å; F431-F456 AromaticContact CD2-CE2 3.74Å; F431-F456 HydrophobicContact CD2-CE2 3.74Å; F431-F456 AromaticContact CE2-CD2 3.73Å; F431-F456 HydrophobicContact CE2-CD2 3.73Å; F431-F456 AromaticContact CE2-CE2 3.85Å; F431-F456 HydrophobicContact CE2-CE2 3.85Å; L454-F456 HydrophobicContact CB-CE2 3.92Å; L454-F456 HydrophobicContact CB-CZ 4.49Å; F456-L458 HydrophobicContact CB-CD2 4.06Å; F456-E464 HydrophobicContact CD1-CB 4.1Å; F456-E464 HydrophobicContact CE1-CB 4.23Å; F456-E464 WeakPolarHBondContact CE1-O 3.33Å; F456-E464 HydrophobicContact CG-CB 4.35Å; F456-P467 HydrophobicContact CD1-CB 4.3Å; F456-P467 HydrophobicContact CE1-CB 3.95Å; F456-P467 HydrophobicContact CE1-CG 4.36Å; F456-P467 HydrophobicContact CE2-CB 4.33Å; F456-P467 HydrophobicContact CZ-CB 3.96Å; F456-P467 HydrophobicContact CZ-CG 4.39Å
457N98.4Very high97.7Very high7 Ų754.9 Ų54.94%0.03728%0.28CS..EExtended strand (participates in β ladder)trans-98.9104.8169-179.9-9.6000108.2Y428 E459 D460 D461 L468 E474Y428-N457 HydrophobicContact CD1-CB 4.09Å; Y428-N457 HydrophobicContact CE1-CB 3.87Å; N457-E459 PolarHBondContact O-N 2.65Å; N457-E459 WeakPolarHBondContact OD1-CB 3.31Å; N457-E459 PolarHBondContact OD1-N 2.99Å; N457-D460 PolarHBondContact ND2-OD2 2.89Å; N457-D460 PolarHBondContact O-N 2.8Å; N457-D461 PolarHBondContact O-N 2.91Å; N457-L468 HydrophobicContact CB-CD2 4.37Å; N457-E474 PolarHBondContact ND2-OE1 3.13Å
458L97.8Very high97.7Very high6 Ų651.8 Ų51.83%0.03127%0.267CS..THydrogen-bonded Turntrans-77.6-6.9-175.2-51.9-170.3000113.6E338 R424 R427 K429 F456 D461 I462 E464E338-L458 VanDerWaalsContact CD-CD1 3.44Å; E338-L458 HydrophobicContact CG-CD1 3.83Å; E338-L458 WeakPolarHBondContact OE2-CD1 3.18Å; R424-L458 VanDerWaalsContact NH1-CB 3.32Å; R427-L458 PolarHBondContact O-N 3.24Å; K429-L458 HydrophobicContact CB-CD1 4.09Å; K429-L458 HydrophobicContact CB-CD2 4.34Å; K429-L458 HydrophobicContact CB-CG 4.15Å; K429-L458 HydrophobicContact CD-CD1 4.01Å; F456-L458 HydrophobicContact CB-CD2 4.06Å; L458-D461 WeakPolarHBondContact CD2-O 3.44Å; L458-I462 WeakPolarHBondContact O-CG2 3.49Å; L458-E464 HydrophobicContact CD2-CG 3.68Å
459E95.6Very high97.7Very high127 Ų12755.8 Ų55.859%0.59328%0.283SS*.THydrogen-bonded Turntrans-71.8-37.7170.2-169.3173.6178.500110.4R427 N457R427-E459 HydrophobicContact CB-CB 4.17Å; R427-E459 WeakPolarHBondContact CD-OE2 3.46Å; R427-E459 IonicContact CZ-OE2 3.7Å; R427-E459 IonicContact NE-OE2 3.61Å; R427-E459 IonicContact NH1-OE2 2.72Å; R427-E459 PolarHBondContact NH1-OE2 2.96Å; N457-E459 PolarHBondContact O-N 2.65Å; N457-E459 WeakPolarHBondContact OD1-CB 3.31Å; N457-E459 PolarHBondContact OD1-N 2.99Å
460D95.9Very high97.6Very high132 Ų13254 Ų5471%0.70627%0.27SS*.THydrogen-bonded Turntrans-95.8-28.2-179.7-58-42.4000112.7N457N457-D460 PolarHBondContact ND2-OD2 2.89Å; N457-D460 PolarHBondContact O-N 2.8Å
461D97.4Very high97.5Very high30 Ų3056.2 Ų56.216%0.1630%0.3CS..  trans-137.774.8-173.3-178.117.5000111.8N457 L458 A463 E464 A465 V466N457-D461 PolarHBondContact O-N 2.91Å; L458-D461 WeakPolarHBondContact CD2-O 3.44Å; D461-A463 PolarHBondContact O-N 3.21Å; D461-A463 PolarHBondContact OD1-N 2.88Å; D461-E464 PolarHBondContact O-N 3.03Å; D461-E464 PolarHBondContact OD1-N 3.42Å; D461-A465 VanDerWaalsContact CG-N 3.32Å; D461-A465 PolarHBondContact OD1-N 3.33Å; D461-A465 VanDerWaalsContact OD1-N 3.13Å; D461-A465 WeakPolarHBondContact OD2-CA 2.93Å; D461-A465 PolarHBondContact OD2-N 3.14Å; D461-V466 PolarHBondContact OD2-N 3.04Å
462I96.4Very high97.6Very high78 Ų7848 Ų4840%0.427%0.272SS..THydrogen-bonded Turntrans-62.7-19.1174.660.7171.2000113.4A318 F319 L458 E464A318-I462 HydrophobicContact CB-CD1 3.62Å; F319-I462 HydrophobicContact CD1-CB 4.37Å; F319-I462 WeakPolarHBondContact CD1-O 3.31Å; F319-I462 HydrophobicContact CE1-CB 3.96Å; F319-I462 HydrophobicContact CE1-CG2 4.44Å; L458-I462 WeakPolarHBondContact O-CG2 3.49Å; I462-E464 VanDerWaalsContact C-N 3.32Å
463A97.5Very high97.6Very high20 Ų2049.8 Ų49.817%0.16529%0.294CS..THydrogen-bonded Turntrans-88.2-2.9-176.900000112.7G321 V322 D461 A465G321-A463 CarbonylContact C-O 3.56Å; G321-A463 VanDerWaalsContact CA-O 3.25Å; G321-A463 WeakPolarHBondContact CA-O 3.35Å; G321-A463 PolarHBondContact N-O 2.87Å; G321-A463 VanDerWaalsContact N-O 3.14Å; V322-A463 HydrophobicContact CG2-CB 4.05Å; V322-A463 PolarHBondContact N-O 2.75Å; D461-A463 PolarHBondContact O-N 3.21Å; D461-A463 PolarHBondContact OD1-N 2.88Å; A463-A465 VanDerWaalsContact C-N 3.25Å; A463-A465 PolarHBondContact O-N 2.71Å
464E98.6Very high97.6Very high0 Ų053.2 Ų53.20%031%0.31CS..  trans51.747-177-56.6170.4112.300111W323 W337 E338 K429 F431 F456 L458 D461 I462W323-E464 WeakPolarHBondContact CB-O 3.43Å; W323-E464 PolarHBondContact N-O 3.13Å; W337-E464 HydrophobicContact CE3-CB 3.98Å; W337-E464 HydrophobicContact CE3-CG 4.37Å; W337-E464 HydrophobicContact CZ3-CB 3.97Å; E338-E464 WeakPolarHBondContact CB-OE2 3.21Å; E338-E464 VanDerWaalsContact CG-CD 3.48Å; E338-E464 HydrophobicContact CG-CG 4.12Å; E338-E464 WeakPolarHBondContact CG-OE2 3.13Å; E338-E464 PolarHBondContact N-OE2 3.43Å; K429-E464 WeakPolarHBondContact CD-OE1 3.33Å; K429-E464 WeakPolarHBondContact CE-OE1 3.21Å; K429-E464 IonicContact NZ-OE1 3.66Å; K429-E464 PolarHBondContact NZ-OE1 3.18Å; K429-E464 IonicContact NZ-OE2 3.58Å; F431-E464 VanDerWaalsContact CZ-OE1 3.27Å; F431-E464 WeakPolarHBondContact CZ-OE1 3.39Å; F456-E464 HydrophobicContact CD1-CB 4.1Å; F456-E464 HydrophobicContact CE1-CB 4.23Å; F456-E464 WeakPolarHBondContact CE1-O 3.33Å; F456-E464 HydrophobicContact CG-CB 4.35Å; L458-E464 HydrophobicContact CD2-CG 3.68Å; D461-E464 PolarHBondContact O-N 3.03Å; D461-E464 PolarHBondContact OD1-N 3.42Å; I462-E464 VanDerWaalsContact C-N 3.32Å
465A98.3Very high97.6Very high22 Ų2252.6 Ų52.618%0.18231%0.307CS..  trans-84.7-42.9-175.400000113V322 D461 A463V322-A465 HydrophobicContact CB-CB 3.79Å; V322-A465 HydrophobicContact CG1-CB 3.97Å; V322-A465 HydrophobicContact CG2-CB 4.43Å; D461-A465 VanDerWaalsContact CG-N 3.32Å; D461-A465 PolarHBondContact OD1-N 3.33Å; D461-A465 VanDerWaalsContact OD1-N 3.13Å; D461-A465 WeakPolarHBondContact OD2-CA 2.93Å; D461-A465 PolarHBondContact OD2-N 3.14Å; A463-A465 VanDerWaalsContact C-N 3.25Å; A463-A465 PolarHBondContact O-N 2.71Å
466V98.1Very high97.6Very high95 Ų9557.7 Ų57.758%0.57633%0.331SS*.SBendtrans-133.5113.1-171.6-173.80000110.1D461D461-V466 PolarHBondContact OD2-N 3.04Å
467P98.3Very high97.6Very high30 Ų3060.3 Ų60.320%0.19535%0.352CS..PPolyproline II helixtrans-70.4151.717430.8-34.6000110.3L454 I455 F456L454-P467 HydrophobicContact CB-CB 4.17Å; L454-P467 HydrophobicContact CD2-CB 4.4Å; L454-P467 HydrophobicContact CD2-CG 4.34Å; I455-P467 CarbonylContact O-C 3.51Å; I455-P467 VanDerWaalsContact O-CA 3.32Å; I455-P467 WeakPolarHBondContact O-CA 3.43Å; F456-P467 HydrophobicContact CD1-CB 4.3Å; F456-P467 HydrophobicContact CE1-CB 3.95Å; F456-P467 HydrophobicContact CE1-CG 4.36Å; F456-P467 HydrophobicContact CE2-CB 4.33Å; F456-P467 HydrophobicContact CZ-CB 3.96Å; F456-P467 HydrophobicContact CZ-CG 4.39Å
468L98.6Very high97.6Very high32 Ų3260.3 Ų60.317%0.16835%0.352CS..PPolyproline II helixtrans-54.9139.4172.3-63.2-177.7000111.3Y428 I455 N457 R470 E474 Y475Y428-L468 HydrophobicContact CD1-CD1 4.13Å; Y428-L468 HydrophobicContact CE1-CD1 4.05Å; I455-L468 HydrophobicContact CB-CD1 4.32Å; I455-L468 HydrophobicContact CG2-CD1 3.87Å; I455-L468 WeakPolarHBondContact O-CB 3.3Å; I455-L468 WeakPolarHBondContact O-CG 2.97Å; I455-L468 PolarHBondContact O-N 3.08Å; N457-L468 HydrophobicContact CB-CD2 4.37Å; L468-R470 PolarHBondContact O-N 3.13Å; L468-E474 HydrophobicContact CD1-CB 4.44Å; L468-E474 HydrophobicContact CD1-CG 3.87Å; L468-E474 WeakPolarHBondContact CD2-OE2 3.49Å; L468-Y475 HydrophobicContact CB-CD2 4.03Å
469E97.8Very high97.6Very high148 Ų14860.5 Ų60.569%0.69235%0.353SS*.PPolyproline II helixtrans-62.6123.4174.9-73-62.9151.800110.8G471 G472 Y475E469-G471 PolarHBondContact O-N 3.32Å; E469-G471 VanDerWaalsContact O-N 3.13Å; E469-G472 WeakPolarHBondContact O-CA 3.5Å; E469-G472 PolarHBondContact O-N 3.04Å; E469-Y475 WeakPolarHBondContact O-CB 3.33Å
470R95.1Very high97.7Very high115 Ų11558 Ų5843%0.43435%0.349SS..THydrogen-bonded Turntrans-58.8-31.5-174.1-69.5179.6174.1166.1-0.6113.6L452 L468 G472 Y475 Q476L452-R470 PolarHBondContact O-NH2 3.33Å; L468-R470 PolarHBondContact O-N 3.13Å; R470-G472 VanDerWaalsContact C-N 3.34Å; R470-Y475 HydrophobicContact CB-CD1 4.31Å; R470-Y475 HydrophobicContact CB-CE1 4.17Å; R470-Y475 HydrophobicContact CG-CE1 4.16Å; R470-Y475 HydrophobicContact CG-CE2 4.14Å; R470-Y475 WeakPolarHBondContact O-CD1 3.06Å; R470-Q476 PolarHBondContact O-NE2 3.14Å
471G95.4Very high97.9Very high73 Ų7357.6 Ų57.675%0.75334%0.34SS*.THydrogen-bonded Turntrans-83.4-8.8176.400000114.1E469E469-G471 PolarHBondContact O-N 3.32Å; E469-G471 VanDerWaalsContact O-N 3.13Å
472G97.6Very high97.9Very high26 Ų2656.1 Ų56.127%0.26833%0.333SS..SBendtrans-71149-177.300000112.9E469 R470 E474 Y475 Q476E469-G472 WeakPolarHBondContact O-CA 3.5Å; E469-G472 PolarHBondContact O-N 3.04Å; R470-G472 VanDerWaalsContact C-N 3.34Å; G472-E474 VanDerWaalsContact C-N 3.26Å; G472-E474 PolarHBondContact O-N 3.14Å; G472-Y475 PolarHBondContact O-N 2.86Å; G472-Q476 WeakPolarHBondContact O-CG 3.42Å; G472-Q476 PolarHBondContact O-N 3.02Å; G472-Q476 VanDerWaalsContact O-N 3.09Å
473A98.3Very high98Very high90 Ų9058 Ų5874%0.74434%0.335SS*.Hα-helixtrans-56.8-39.3179.200000112.6Q476 A477A473-Q476 PolarHBondContact O-N 3.13Å; A473-A477 WeakPolarHBondContact O-CB 3.45Å; A473-A477 PolarHBondContact O-N 2.91Å
474E98.3Very high98.1Very high72 Ų7263.6 Ų63.634%0.33636%0.355SS..Hα-helixtrans-64.1-48.5178.4-171.6175.2-160.400112Y428 N457 L468 G472 Q476 A477 V478Y428-E474 HydrophobicContact CE1-CG 4.05Å; Y428-E474 WeakPolarHBondContact CE1-OE1 3.48Å; Y428-E474 VanDerWaalsContact CZ-OE1 3.25Å; Y428-E474 PolarHBondContact OH-OE1 3.18Å; N457-E474 PolarHBondContact ND2-OE1 3.13Å; L468-E474 HydrophobicContact CD1-CB 4.44Å; L468-E474 HydrophobicContact CD1-CG 3.87Å; L468-E474 WeakPolarHBondContact CD2-OE2 3.49Å; G472-E474 VanDerWaalsContact C-N 3.26Å; G472-E474 PolarHBondContact O-N 3.14Å; E474-Q476 VanDerWaalsContact C-N 3.33Å; E474-Q476 PolarHBondContact O-N 2.93Å; E474-A477 PolarHBondContact O-N 2.89Å; E474-V478 VanDerWaalsContact O-CG2 3.31Å; E474-V478 WeakPolarHBondContact O-CG2 3.39Å; E474-V478 PolarHBondContact O-N 2.88Å
475Y98.7Very high98.1Very high2 Ų265 Ų651%0.00836%0.364CS..Hα-helixtrans-58-46.7177-175.1-86.8000111.6L452 P453 I455 L468 E469 R470 G472 A477 V478 L479L452-Y475 WeakPolarHBondContact CB-OH 3.48Å; P453-Y475 WeakPolarHBondContact O-CE2 3.25Å; P453-Y475 PolarHBondContact O-OH 2.9Å; I455-Y475 HydrophobicContact CB-CD2 4.12Å; I455-Y475 HydrophobicContact CB-CE2 4.05Å; I455-Y475 HydrophobicContact CD1-CD2 3.83Å; I455-Y475 HydrophobicContact CD1-CE2 3.55Å; I455-Y475 HydrophobicContact CG1-CD2 4.11Å; I455-Y475 HydrophobicContact CG1-CE2 3.64Å; L468-Y475 HydrophobicContact CB-CD2 4.03Å; E469-Y475 WeakPolarHBondContact O-CB 3.33Å; R470-Y475 HydrophobicContact CB-CD1 4.31Å; R470-Y475 HydrophobicContact CB-CE1 4.17Å; R470-Y475 HydrophobicContact CG-CE1 4.16Å; R470-Y475 HydrophobicContact CG-CE2 4.14Å; R470-Y475 WeakPolarHBondContact O-CD1 3.06Å; G472-Y475 PolarHBondContact O-N 2.86Å; Y475-A477 VanDerWaalsContact C-N 3.29Å; Y475-A477 PolarHBondContact O-N 3.02Å; Y475-V478 PolarHBondContact O-N 2.78Å; Y475-L479 HydrophobicContact CD1-CB 4.46Å; Y475-L479 HydrophobicContact CE1-CB 4.21Å; Y475-L479 HydrophobicContact CE1-CD2 3.83Å; Y475-L479 HydrophobicContact CE1-CG 4.43Å; Y475-L479 WeakPolarHBondContact O-CB 3.4Å; Y475-L479 PolarHBondContact O-N 2.94Å
476Q98.4Very high98.1Very high107 Ų10765 Ų6550%0.536%0.36SS..Hα-helixtrans-64.4-32.9-180-67.5-63.5-28.800112.5R470 G472 A473 E474 P480R470-Q476 PolarHBondContact O-NE2 3.14Å; G472-Q476 WeakPolarHBondContact O-CG 3.42Å; G472-Q476 PolarHBondContact O-N 3.02Å; G472-Q476 VanDerWaalsContact O-N 3.09Å; A473-Q476 PolarHBondContact O-N 3.13Å; E474-Q476 VanDerWaalsContact C-N 3.33Å; E474-Q476 PolarHBondContact O-N 2.93Å; Q476-P480 WeakPolarHBondContact O-CD 3.37Å
477A98.4Very high98.1Very high54 Ų5463.1 Ų63.145%0.44636%0.355SS..Hα-helixtrans-74-33.4176.200000113.1A473 E474 Y475A473-A477 WeakPolarHBondContact O-CB 3.45Å; A473-A477 PolarHBondContact O-N 2.91Å; E474-A477 PolarHBondContact O-N 2.89Å; Y475-A477 VanDerWaalsContact C-N 3.29Å; Y475-A477 PolarHBondContact O-N 3.02Å
478V98.4Very high98.1Very high7 Ų765.9 Ų65.94%0.04237%0.368CS..Hα-helixtrans-88-40.2-174.5174.90000112.5Y428 I455 E474 Y475 K481 V482Y428-V478 HydrophobicContact CD1-CG1 4.26Å; Y428-V478 HydrophobicContact CD1-CG2 4.12Å; Y428-V478 HydrophobicContact CD2-CG1 3.93Å; Y428-V478 HydrophobicContact CD2-CG2 3.75Å; Y428-V478 HydrophobicContact CE1-CG2 3.97Å; Y428-V478 HydrophobicContact CE2-CG2 3.58Å; Y428-V478 HydrophobicContact CG-CG1 3.73Å; Y428-V478 HydrophobicContact CG-CG2 4.02Å; I455-V478 HydrophobicContact CD1-CG1 4.27Å; I455-V478 HydrophobicContact CG2-CG1 4.21Å; E474-V478 VanDerWaalsContact O-CG2 3.31Å; E474-V478 WeakPolarHBondContact O-CG2 3.39Å; E474-V478 PolarHBondContact O-N 2.88Å; Y475-V478 PolarHBondContact O-N 2.78Å; V478-K481 WeakPolarHBondContact O-CB 3.41Å; V478-K481 PolarHBondContact O-N 3.2Å; V478-V482 HydrophobicContact CG1-CG2 3.76Å; V478-V482 PolarHBondContact O-N 3.4Å
479L98.6Very high98.1Very high10 Ų1065 Ų655%0.05236%0.364CS..Hα-helixtrans-48.7-49.4-177.1177.464.7000114.8L452 P453 I455 Y475 K481 V482 R483L452-L479 HydrophobicContact CD2-CD2 4.16Å; P453-L479 HydrophobicContact CG-CD1 3.62Å; I455-L479 HydrophobicContact CD1-CB 4.36Å; I455-L479 HydrophobicContact CD1-CD1 4.46Å; Y475-L479 HydrophobicContact CD1-CB 4.46Å; Y475-L479 HydrophobicContact CE1-CB 4.21Å; Y475-L479 HydrophobicContact CE1-CD2 3.83Å; Y475-L479 HydrophobicContact CE1-CG 4.43Å; Y475-L479 WeakPolarHBondContact O-CB 3.4Å; Y475-L479 PolarHBondContact O-N 2.94Å; L479-K481 VanDerWaalsContact C-N 3.26Å; L479-K481 PolarHBondContact O-N 3.26Å; L479-V482 PolarHBondContact O-N 2.92Å; L479-R483 HydrophobicContact CD1-CG 4.25Å; L479-R483 WeakPolarHBondContact O-CG 3.17Å; L479-R483 PolarHBondContact O-N 3.44Å
480P98.6Very high98.1Very high76 Ų7661.7 Ų61.749%0.49435%0.351SS..Hα-helixtrans-64.5-31.6-179.824.5-33.9000112.5Q476 K484Q476-P480 WeakPolarHBondContact O-CD 3.37Å; P480-K484 WeakPolarHBondContact O-CB 3.36Å; P480-K484 PolarHBondContact O-N 3.22Å
481K98.7Very high98.2Very high122 Ų12261.5 Ų61.553%0.5336%0.355SS..Hα-helixtrans-69.3-46.3176.4-57.3177.6-177.6175.60110.8L425 V478 L479 R483 K484 V485L425-K481 HydrophobicContact CD2-CB 3.57Å; V478-K481 WeakPolarHBondContact O-CB 3.41Å; V478-K481 PolarHBondContact O-N 3.2Å; L479-K481 VanDerWaalsContact C-N 3.26Å; L479-K481 PolarHBondContact O-N 3.26Å; K481-R483 VanDerWaalsContact C-N 3.34Å; K481-R483 PolarHBondContact O-N 2.81Å; K481-K484 PolarHBondContact O-N 3.42Å; K481-V485 WeakPolarHBondContact O-CG2 3.21Å; K481-V485 PolarHBondContact O-N 3.5Å
482V98.6Very high98.3Very high0 Ų060.1 Ų60.10%033%0.33CS..Hα-helixtrans-57.1-46.9175.3168.80000111.2V423 L425 A430 Y432 V478 L479 K484 V485 L486V423-V482 HydrophobicContact CB-CG1 4.47Å; L425-V482 HydrophobicContact CB-CG2 4.49Å; L425-V482 HydrophobicContact CD2-CG2 4.06Å; A430-V482 HydrophobicContact CB-CB 4.43Å; A430-V482 HydrophobicContact CB-CG1 3.5Å; A430-V482 VanDerWaalsContact CB-CG1 3.5Å; A430-V482 HydrophobicContact CB-CG2 4.08Å; Y432-V482 HydrophobicContact CE2-CG1 4.27Å; V478-V482 HydrophobicContact CG1-CG2 3.76Å; V478-V482 PolarHBondContact O-N 3.4Å; L479-V482 PolarHBondContact O-N 2.92Å; V482-K484 VanDerWaalsContact C-N 3.33Å; V482-K484 PolarHBondContact O-N 3.08Å; V482-V485 VanDerWaalsContact O-CG2 3.28Å; V482-V485 WeakPolarHBondContact O-CG2 3.15Å; V482-V485 PolarHBondContact O-N 3.38Å; V482-L486 WeakPolarHBondContact O-CB 3.33Å; V482-L486 PolarHBondContact O-N 3.25Å; V482-L486 VanDerWaalsContact O-N 3.08Å
483R98.4Very high98.3Very high117 Ų11759.5 Ų59.544%0.44232%0.321SS..Hα-helixtrans-59.5-44.8176.9-78.9175.9169.2176.2-5.1112.2Y432 L479 K481 A487Y432-R483 VanDerWaalsContact OH-CG 3.22Å; Y432-R483 WeakPolarHBondContact OH-CG 3.04Å; L479-R483 HydrophobicContact CD1-CG 4.25Å; L479-R483 WeakPolarHBondContact O-CG 3.17Å; L479-R483 PolarHBondContact O-N 3.44Å; K481-R483 VanDerWaalsContact C-N 3.34Å; K481-R483 PolarHBondContact O-N 2.81Å; R483-A487 WeakPolarHBondContact O-CB 3.24Å; R483-A487 PolarHBondContact O-N 2.97Å
484K98.6Very high98.2Very high137 Ų13758.7 Ų58.760%0.59631%0.314SS*.Hα-helixtrans-62.3-52.6179.7-176.7177-177.1-175.70111.3P480 K481 V482 L486 A487 D488P480-K484 WeakPolarHBondContact O-CB 3.36Å; P480-K484 PolarHBondContact O-N 3.22Å; K481-K484 PolarHBondContact O-N 3.42Å; V482-K484 VanDerWaalsContact C-N 3.33Å; V482-K484 PolarHBondContact O-N 3.08Å; K484-L486 VanDerWaalsContact C-N 3.27Å; K484-L486 PolarHBondContact O-N 3.41Å; K484-A487 PolarHBondContact O-N 3.3Å; K484-A487 VanDerWaalsContact O-N 3.17Å; K484-D488 WeakPolarHBondContact CG-OD2 3.12Å; K484-D488 WeakPolarHBondContact O-CB 3.33Å; K484-D488 PolarHBondContact O-N 2.94Å
485V98.4Very high98.1Very high31 Ų3159.9 Ų59.919%0.18832%0.322CS..Hα-helixtrans-63.6-33.8-177.8-60.70000112.5V405 F407 V423 L425 K481 V482 V489V405-V485 HydrophobicContact CG1-CB 4.31Å; V405-V485 HydrophobicContact CG1-CG2 4.2Å; V405-V485 HydrophobicContact CG2-CB 4.37Å; V405-V485 HydrophobicContact CG2-CG1 4.07Å; F407-V485 WeakPolarHBondContact CZ-O 3.2Å; V423-V485 HydrophobicContact CG1-CG2 3.77Å; L425-V485 HydrophobicContact CD1-CG1 4.36Å; K481-V485 WeakPolarHBondContact O-CG2 3.21Å; K481-V485 PolarHBondContact O-N 3.5Å; V482-V485 VanDerWaalsContact O-CG2 3.28Å; V482-V485 WeakPolarHBondContact O-CG2 3.15Å; V482-V485 PolarHBondContact O-N 3.38Å; V485-V489 PolarHBondContact O-N 2.73Å; V485-V489 VanDerWaalsContact O-N 3.08Å
486L98.3Very high97.9Very high20 Ų2060.8 Ų60.811%0.10533%0.328CS..Hα-helixtrans-67.2-45.8174.2-17856.8000111.9F407 L420 V423 Y432 V482 K484 D488 V489 L490F407-L486 HydrophobicContact CE1-CD1 4.41Å; L420-L486 HydrophobicContact CB-CD1 4.19Å; L420-L486 WeakPolarHBondContact O-CD1 3.21Å; V423-L486 HydrophobicContact CG2-CB 4.09Å; V423-L486 HydrophobicContact CG2-CD1 4Å; V423-L486 HydrophobicContact CG2-CD2 4.4Å; V423-L486 HydrophobicContact CG2-CG 4.39Å; Y432-L486 HydrophobicContact CD2-CD2 3.78Å; Y432-L486 HydrophobicContact CE2-CD2 3.48Å; Y432-L486 VanDerWaalsContact CE2-CD2 3.48Å; V482-L486 WeakPolarHBondContact O-CB 3.33Å; V482-L486 PolarHBondContact O-N 3.25Å; V482-L486 VanDerWaalsContact O-N 3.08Å; K484-L486 VanDerWaalsContact C-N 3.27Å; K484-L486 PolarHBondContact O-N 3.41Å; L486-D488 VanDerWaalsContact C-N 3.33Å; L486-D488 PolarHBondContact O-N 3.12Å; L486-V489 HydrophobicContact CD1-CG1 4.32Å; L486-V489 WeakPolarHBondContact O-CG1 3.37Å; L486-L490 HydrophobicContact CD1-CD1 4.03Å; L486-L490 HydrophobicContact CD1-CG 4.21Å; L486-L490 HydrophobicContact CG-CD1 4.08Å; L486-L490 VanDerWaalsContact O-CG 3.27Å; L486-L490 WeakPolarHBondContact O-CG 3.31Å; L486-L490 PolarHBondContact O-N 2.04Å; L486-L490 VanDerWaalsContact O-N 3.14Å
487A98.4Very high97.7Very high56 Ų5660.1 Ų60.146%0.46333%0.327SS..Hα-helixtrans-62.8-42.6176.900000111.5R483 K484 L490 Q491R483-A487 WeakPolarHBondContact O-CB 3.24Å; R483-A487 PolarHBondContact O-N 2.97Å; K484-A487 PolarHBondContact O-N 3.3Å; K484-A487 VanDerWaalsContact O-N 3.17Å; A487-L490 PolarHBondContact O-N 3.4Å; A487-Q491 WeakPolarHBondContact O-CB 3.39Å; A487-Q491 PolarHBondContact O-N 2.78Å
488D98.4Very high97.5Very high89 Ų8961.9 Ų61.948%0.47633%0.328SS..Hα-helixtrans-61.6-45.8-180-69.1-13000111K484 L486 Q491 D492K484-D488 WeakPolarHBondContact CG-OD2 3.12Å; K484-D488 WeakPolarHBondContact O-CB 3.33Å; K484-D488 PolarHBondContact O-N 2.94Å; L486-D488 VanDerWaalsContact C-N 3.33Å; L486-D488 PolarHBondContact O-N 3.12Å; D488-Q491 PolarHBondContact O-N 3.38Å; D488-D492 VanDerWaalsContact O-CB 3.27Å; D488-D492 WeakPolarHBondContact O-CB 3.32Å; D488-D492 PolarHBondContact O-N 2.94Å
489V97.9Very high97.5Very high13 Ų1362 Ų628%0.07933%0.329CS..Hα-helixtrans-68.8-37.8179.174.90000112.7F407 L420 V485 L486 Q491 D492 I493F407-V489 HydrophobicContact CD1-CG1 3.81Å; F407-V489 HydrophobicContact CD2-CB 4.28Å; F407-V489 HydrophobicContact CD2-CG1 4.2Å; F407-V489 HydrophobicContact CD2-CG2 3.89Å; F407-V489 HydrophobicContact CE1-CB 4.05Å; F407-V489 HydrophobicContact CE1-CG1 3.34Å; F407-V489 HydrophobicContact CE2-CB 3.59Å; F407-V489 HydrophobicContact CE2-CG1 3.77Å; F407-V489 HydrophobicContact CE2-CG2 3.58Å; F407-V489 HydrophobicContact CG-CG1 4.22Å; F407-V489 HydrophobicContact CZ-CB 3.46Å; F407-V489 VanDerWaalsContact CZ-CB 3.46Å; F407-V489 HydrophobicContact CZ-CG1 3.31Å; F407-V489 HydrophobicContact CZ-CG2 4Å; L420-V489 HydrophobicContact CD1-CG1 3.9Å; L420-V489 HydrophobicContact CD1-CG2 4.27Å; V485-V489 PolarHBondContact O-N 2.73Å; V485-V489 VanDerWaalsContact O-N 3.08Å; L486-V489 HydrophobicContact CD1-CG1 4.32Å; L486-V489 WeakPolarHBondContact O-CG1 3.37Å; V489-Q491 VanDerWaalsContact C-N 3.32Å; V489-Q491 PolarHBondContact O-N 3.07Å; V489-D492 WeakPolarHBondContact O-CB 3.44Å; V489-D492 PolarHBondContact O-N 2.6Å; V489-I493 HydrophobicContact CG2-CD1 4.05Å; V489-I493 HydrophobicContact CG2-CG1 4.4Å; V489-I493 VanDerWaalsContact O-CG1 3.31Å; V489-I493 WeakPolarHBondContact O-CG1 3.4Å; V489-I493 PolarHBondContact O-N 3.23Å
490L98Very high97.4Very high78 Ų7866.5 Ų66.541%0.40836%0.362SS..Hα-helixtrans-66.4-39.8178.9-70.4173.2000110.7L420 L486 A487 A494L420-L490 HydrophobicContact CB-CD2 4.3Å; L486-L490 HydrophobicContact CD1-CD1 4.03Å; L486-L490 HydrophobicContact CD1-CG 4.21Å; L486-L490 HydrophobicContact CG-CD1 4.08Å; L486-L490 VanDerWaalsContact O-CG 3.27Å; L486-L490 WeakPolarHBondContact O-CG 3.31Å; L486-L490 PolarHBondContact O-N 2.04Å; L486-L490 VanDerWaalsContact O-N 3.14Å; A487-L490 PolarHBondContact O-N 3.4Å; L490-A494 WeakPolarHBondContact O-CB 3.43Å; L490-A494 PolarHBondContact O-N 3.45Å
491Q98Very high97.3Very high111 Ų11163.4 Ų63.452%0.51934%0.343SS..Hα-helixtrans-67.9-37.1173.7-174.260.370.400112.1A487 D488 V489 A494 N495A487-Q491 WeakPolarHBondContact O-CB 3.39Å; A487-Q491 PolarHBondContact O-N 2.78Å; D488-Q491 PolarHBondContact O-N 3.38Å; V489-Q491 VanDerWaalsContact C-N 3.32Å; V489-Q491 PolarHBondContact O-N 3.07Å; Q491-A494 PolarHBondContact O-N 3.39Å; Q491-N495 PolarHBondContact NE2-ND2 3.03Å; Q491-N495 PolarHBondContact NE2-OD1 3.35Å; Q491-N495 WeakPolarHBondContact O-CB 3.46Å; Q491-N495 PolarHBondContact O-N 3.35Å; Q491-N495 VanDerWaalsContact O-N 3.13Å; Q491-N495 PolarHBondContact O-ND2 3.41Å; Q491-N495 VanDerWaalsContact O-ND2 3.08Å
492D97.6Very high97.3Very high45 Ų4560.6 Ų60.624%0.24133%0.333CS..Hα-helixtrans-62.3-46.8175.3-177.799000111.8R99 R385 D488 V489 N495 D496R99-D492 IonicContact CZ-OD2 2.81Å; R99-D492 IonicContact NH1-OD2 3.98Å; R99-D492 PolarHBondContact NH1-OD2 3.38Å; R99-D492 IonicContact NH2-OD2 3.29Å; R99-D492 PolarHBondContact NH2-OD2 2.8Å; R385-D492 WeakPolarHBondContact CD-OD1 3.4Å; R385-D492 WeakPolarHBondContact CD-OD2 3.37Å; R385-D492 IonicContact CZ-OD1 3.59Å; R385-D492 IonicContact NE-OD1 3.7Å; R385-D492 IonicContact NH1-OD1 2.71Å; R385-D492 PolarHBondContact NH1-OD1 2.92Å; D488-D492 VanDerWaalsContact O-CB 3.27Å; D488-D492 WeakPolarHBondContact O-CB 3.32Å; D488-D492 PolarHBondContact O-N 2.94Å; V489-D492 WeakPolarHBondContact O-CB 3.44Å; V489-D492 PolarHBondContact O-N 2.6Å; D492-N495 PolarHBondContact O-N 2.91Å; D492-D496 PolarHBondContact O-N 3.35Å
493I97.3Very high97.1Very high13 Ų1363 Ų637%0.06734%0.343CS..Hα-helixtrans-62.1-45.2175.4-69167000110.8L98 R99 L420 V489 N495 D496 I498L98-I493 HydrophobicContact CB-CD1 4.31Å; L98-I493 HydrophobicContact CB-CG2 4.11Å; L98-I493 HydrophobicContact CD1-CD1 4.18Å; R99-I493 HydrophobicContact CG-CG1 4.16Å; R99-I493 HydrophobicContact CG-CG2 4.45Å; R99-I493 VanDerWaalsContact CZ-CG1 3.47Å; L420-I493 HydrophobicContact CD1-CD1 3.69Å; V489-I493 HydrophobicContact CG2-CD1 4.05Å; V489-I493 HydrophobicContact CG2-CG1 4.4Å; V489-I493 VanDerWaalsContact O-CG1 3.31Å; V489-I493 WeakPolarHBondContact O-CG1 3.4Å; V489-I493 PolarHBondContact O-N 3.23Å; I493-N495 PolarHBondContact O-N 3.09Å; I493-D496 WeakPolarHBondContact O-CB 3.26Å; I493-D496 PolarHBondContact O-N 3.18Å; I493-D496 VanDerWaalsContact O-N 3.08Å; I493-I498 HydrophobicContact CG2-CG2 4.25Å
494A95.6Very high97.1Very high72 Ų7261.3 Ų61.360%0.59535%0.346SS*.Hα-helixtrans-62.4-23.9178.600000113.4L490 Q491L490-A494 WeakPolarHBondContact O-CB 3.43Å; L490-A494 PolarHBondContact O-N 3.45Å; Q491-A494 PolarHBondContact O-N 3.39Å
495N95.6Very high97Very high97 Ų9760.8 Ų60.852%0.51935%0.345SS..THydrogen-bonded Turntrans-984.7178.6-69.3-26.9000113.5Q491 D492 I493Q491-N495 PolarHBondContact NE2-ND2 3.03Å; Q491-N495 PolarHBondContact NE2-OD1 3.35Å; Q491-N495 WeakPolarHBondContact O-CB 3.46Å; Q491-N495 PolarHBondContact O-N 3.35Å; Q491-N495 VanDerWaalsContact O-N 3.13Å; Q491-N495 PolarHBondContact O-ND2 3.41Å; Q491-N495 VanDerWaalsContact O-ND2 3.08Å; D492-N495 PolarHBondContact O-N 2.91Å; I493-N495 PolarHBondContact O-N 3.09Å
496D95.4Very high96.9Very high22 Ų2262.5 Ų62.512%0.11835%0.354CS..SBendtrans-96.2162179.4-170.326000111.4R95 R99 R385 D492 I493 I498R95-D496 IonicContact CZ-OD2 2.76Å; R95-D496 IonicContact NH1-OD1 3.4Å; R95-D496 IonicContact NH1-OD2 3.53Å; R95-D496 PolarHBondContact NH1-OD2 2.8Å; R95-D496 IonicContact NH2-OD2 3.38Å; R99-D496 WeakPolarHBondContact CD-OD2 3.26Å; R99-D496 IonicContact CZ-OD2 3.07Å; R99-D496 IonicContact NH1-OD2 3.38Å; R99-D496 PolarHBondContact NH1-OD2 3.05Å; R99-D496 VanDerWaalsContact NH1-OD2 3.13Å; R385-D496 HydrophobicContact CG-CB 4.33Å; R385-D496 PolarHBondContact N-OD1 2.75Å; D492-D496 PolarHBondContact O-N 3.35Å; I493-D496 WeakPolarHBondContact O-CB 3.26Å; I493-D496 PolarHBondContact O-N 3.18Å; I493-D496 VanDerWaalsContact O-N 3.08Å; D496-I498 HydrophobicContact CB-CG2 4.4Å; D496-I498 PolarHBondContact O-N 3.45Å; D496-I498 VanDerWaalsContact O-N 3.08Å
497N93.3Very high96.7Very high93 Ų9366.2 Ų66.250%0.49738%0.379SS..  trans-78.590.1168.9-17113.5000108.8R95R95-N497 PolarHBondContact NH2-O 2.95Å
498I96.1Very high96.5Very high90 Ų9068 Ų6846%0.46239%0.388SS..  trans-82.8151.1-179.367.4171.8000111.7R99 I493 D496R99-I498 WeakPolarHBondContact O-CA 2.92Å; I493-I498 HydrophobicContact CG2-CG2 4.25Å; D496-I498 HydrophobicContact CB-CG2 4.4Å; D496-I498 PolarHBondContact O-N 3.45Å; D496-I498 VanDerWaalsContact O-N 3.08Å
499S97.2Very high96.4Very high9 Ų964.5 Ų64.56%0.06337%0.37CS..  trans-105.3158.6172.6-670000110.5R99 N100 G101 N117 E118 R384R99-S499 PolarHBondContact O-N 3.27Å; N100-S499 WeakPolarHBondContact O-CB 3.29Å; G101-S499 WeakPolarHBondContact CA-O 3.27Å; G101-S499 PolarHBondContact N-O 3Å; N117-S499 PolarHBondContact ND2-OG 3.27Å; N117-S499 WeakPolarHBondContact OD1-CB 3.47Å; N117-S499 PolarHBondContact OD1-OG 2.8Å; E118-S499 PolarHBondContact OE1-OG 3.38Å; E118-S499 VanDerWaalsContact OE1-OG 3.08Å; R384-S499 PolarHBondContact NH1-OG 2.79Å
500S96.7Very high96.3Very high106 Ų10665.3 Ų65.374%0.74138%0.375SS*.  trans-128.1124.9175.8-174.20000109.1P115P115-S500 VanDerWaalsContact CG-C 3.48Å; P115-S500 WeakPolarHBondContact CG-O 3.31Å
501A97.4Very high96.2Very high11 Ų1162 Ų629%0.09136%0.358CS..  trans-74.9145.2172.500000111G101 V102 F106 P115 Y503G101-A501 WeakPolarHBondContact O-CB 3.46Å; G101-A501 PolarHBondContact O-N 2.83Å; V102-A501 HydrophobicContact CG2-CB 4.34Å; F106-A501 HydrophobicContact CE1-CB 4.17Å; F106-A501 HydrophobicContact CZ-CB 3.9Å; P115-A501 HydrophobicContact CG-CB 4.16Å; A501-Y503 HydrophobicContact CB-CD2 4.11Å; A501-Y503 HydrophobicContact CB-CE2 3.58Å
502D97.3Very high96.1Very high62 Ų6258.9 Ų58.933%0.33235%0.348SS..  trans-89.8116.316917713.9000108.6G112 T504G112-D502 VanDerWaalsContact CA-O 3.24Å; G112-D502 WeakPolarHBondContact CA-O 3.42Å; D502-T504 WeakPolarHBondContact OD1-CB 3.05Å; D502-T504 PolarHBondContact OD1-N 3.13Å; D502-T504 PolarHBondContact OD1-OG1 3.41Å
503Y96.1Very high96Very high51 Ų5159 Ų5920%0.235%0.351CS..  trans-103.212.3179.6-72.3-74.9000112.7V102 T103 H104 F106 A501 Q505V102-Y503 WeakPolarHBondContact CA-OH 3.24Å; T103-Y503 PolarHBondContact N-OH 2.93Å; H104-Y503 AromaticContact CD2-CD1 3.82Å; H104-Y503 AromaticContact CD2-CE1 3.62Å; H104-Y503 AromaticContact CE1-CD1 3.46Å; H104-Y503 VanDerWaalsContact CE1-CD1 3.46Å; H104-Y503 WeakPolarHBondContact CE1-CD1 3.37Å; H104-Y503 AromaticContact CE1-CD2 3.28Å; H104-Y503 WeakPolarHBondContact CE1-CD2 3.22Å; H104-Y503 AromaticContact CE1-CE1 3.4Å; H104-Y503 WeakPolarHBondContact CE1-CE1 3.42Å; H104-Y503 AromaticContact CE1-CE2 3.19Å; H104-Y503 WeakPolarHBondContact CE1-CE2 3.3Å; H104-Y503 AromaticContact CE1-CG 3.38Å; H104-Y503 AromaticContact CE1-CZ 3.24Å; H104-Y503 AromaticContact CG-CE1 3.87Å; H104-Y503 AromaticContact CG-CZ 3.88Å; H104-Y503 PolarHBondContact N-OH 2.02Å; H104-Y503 VanDerWaalsContact N-OH 3.12Å; H104-Y503 AromaticContact ND1-CE1 3.72Å; H104-Y503 AromaticContact ND1-CE2 3.59Å; H104-Y503 AromaticContact ND1-CZ 3.34Å; H104-Y503 VanDerWaalsContact ND1-CZ 3.34Å; H104-Y503 AromaticContact NE2-CD1 3.15Å; H104-Y503 WeakPolarHBondContact NE2-CD1 3Å; H104-Y503 AromaticContact NE2-CD2 3.81Å; H104-Y503 AromaticContact NE2-CE1 3.34Å; H104-Y503 VanDerWaalsContact NE2-CE1 3.34Å; H104-Y503 WeakPolarHBondContact NE2-CE1 3.21Å; H104-Y503 AromaticContact NE2-CE2 3.95Å; H104-Y503 AromaticContact NE2-CG 3.38Å; H104-Y503 AromaticContact NE2-CZ 3.72Å; H104-Y503 WeakPolarHBondContact O-CE1 3.49Å; H104-Y503 PolarHBondContact O-OH 3.46Å; F106-Y503 AromaticContact CD1-CD1 3.69Å; F106-Y503 HydrophobicContact CD1-CD1 3.69Å; F106-Y503 AromaticContact CD1-CE1 3.56Å; F106-Y503 HydrophobicContact CD1-CE1 3.56Å; F106-Y503 AromaticContact CE1-CD1 3.58Å; F106-Y503 HydrophobicContact CE1-CD1 3.58Å; F106-Y503 AromaticContact CE1-CE1 3.28Å; F106-Y503 HydrophobicContact CE1-CE1 3.28Å; F106-Y503 HydrophobicContact CE1-CG 4.42Å; F106-Y503 AromaticContact CE1-CZ 3.93Å; F106-Y503 HydrophobicContact CG-CE1 4.3Å; F106-Y503 AromaticContact CZ-CE1 3.82Å; F106-Y503 HydrophobicContact CZ-CE1 3.82Å; A501-Y503 HydrophobicContact CB-CD2 4.11Å; A501-Y503 HydrophobicContact CB-CE2 3.58Å; Y503-Q505 PolarHBondContact O-N 3.28Å
504T97.4Very high95.8Very high82 Ų8260.5 Ų60.550%0.50336%0.36SS..  trans-55.2137.9173.8-56.90000110.2S110 V111 D502S110-T504 WeakPolarHBondContact CA-O 3.4Å; V111-T504 HydrophobicContact CG2-CG2 4.24Å; V111-T504 PolarHBondContact N-O 3.16Å; D502-T504 WeakPolarHBondContact OD1-CB 3.05Å; D502-T504 PolarHBondContact OD1-N 3.13Å; D502-T504 PolarHBondContact OD1-OG1 3.41Å
505Q96.4Very high95.6Very high126 Ų12661.9 Ų61.959%0.58936%0.362SS*.BIsolated β-bridgetrans-115132179.1-67.8-176.641.400110.8A107 T109 Y503A107-Q505 HydrophobicContact CB-CG 4.45Å; T109-Q505 CarbonylContact O-C 3.44Å; T109-Q505 VanDerWaalsContact O-CA 3.23Å; T109-Q505 WeakPolarHBondContact O-CA 3.49Å; T109-Q505 WeakPolarHBondContact OG1-CG 3.33Å; T109-Q505 PolarHBondContact OG1-OE1 3.16Å; Y503-Q505 PolarHBondContact O-N 3.28Å
506D96.7Very high95.4Very high67 Ų6767.1 Ų67.136%0.35838%0.377SS..  trans-138.9116.9175-172.8-28.6000109T109 V111 S508 V509T109-D506 PolarHBondContact O-N 3.43Å; V111-D506 HydrophobicContact CG2-CB 3.53Å; D506-S508 PolarHBondContact O-N 3.49Å; D506-S508 VanDerWaalsContact OD1-CB 3.25Å; D506-S508 WeakPolarHBondContact OD1-CB 3.02Å; D506-S508 PolarHBondContact OD1-N 3.25Å; D506-S508 PolarHBondContact OD1-OG 2.87Å; D506-S508 PolarHBondContact OD2-OG 2.92Å; D506-V509 HydrophobicContact CB-CG1 4.39Å; D506-V509 WeakPolarHBondContact O-CG2 3.36Å; D506-V509 PolarHBondContact O-N 3.01Å; D506-V509 VanDerWaalsContact O-N 3.11Å
507P93.6Very high95.2Very high98 Ų9869.1 Ų69.164%0.63639%0.385SS*.G310 helixtrans-55-25.8177.6-2735.8000114.5V509 T510P507-V509 PolarHBondContact O-N 2.96Å; P507-T510 VanDerWaalsContact O-CB 3.27Å; P507-T510 WeakPolarHBondContact O-CB 3.15Å; P507-T510 PolarHBondContact O-N 3.01Å; P507-T510 PolarHBondContact O-OG1 2.05Å
508S94.1Very high95Very high94 Ų9466.6 Ų66.666%0.65737%0.373SS*.G310 helixtrans-68-17.7-18070.90000114.1D506 T510D506-S508 PolarHBondContact O-N 3.49Å; D506-S508 VanDerWaalsContact OD1-CB 3.25Å; D506-S508 WeakPolarHBondContact OD1-CB 3.02Å; D506-S508 PolarHBondContact OD1-N 3.25Å; D506-S508 PolarHBondContact OD1-OG 2.87Å; D506-S508 PolarHBondContact OD2-OG 2.92Å; S508-T510 VanDerWaalsContact C-N 3.31Å
509V95.8Very high94.7Very high15 Ų1562.7 Ų62.79%0.09135%0.354CS..G310 helixtrans-88.10.1176.2-55.30000113.4T109 V111 H142 H143 D506 P507T109-V509 VanDerWaalsContact O-CG2 3.26Å; T109-V509 WeakPolarHBondContact O-CG2 3.44Å; V111-V509 HydrophobicContact CG2-CG1 4.22Å; V111-V509 HydrophobicContact CG2-CG2 4.28Å; H142-V509 PolarHBondContact NE2-O 2.9Å; H143-V509 HydrophobicContact CB-CB 4.13Å; D506-V509 HydrophobicContact CB-CG1 4.39Å; D506-V509 WeakPolarHBondContact O-CG2 3.36Å; D506-V509 PolarHBondContact O-N 3.01Å; D506-V509 VanDerWaalsContact O-N 3.11Å; P507-V509 PolarHBondContact O-N 2.96Å
510T95.9Very high94.6Very high30 Ų3063.4 Ų63.418%0.18436%0.359CS..SBendtrans-64.1128177.5-52.70000109.7V199 P507 S508 C512V199-T510 HydrophobicContact CB-CG2 4.07Å; V199-T510 HydrophobicContact CG1-CG2 4.01Å; V199-T510 HydrophobicContact CG2-CG2 3.66Å; P507-T510 VanDerWaalsContact O-CB 3.27Å; P507-T510 WeakPolarHBondContact O-CB 3.15Å; P507-T510 PolarHBondContact O-N 3.01Å; P507-T510 PolarHBondContact O-OG1 2.05Å; S508-T510 VanDerWaalsContact C-N 3.31Å; T510-C512 PolarHBondContact O-N 3.13Å
511P96.1Very high94.4Very high8 Ų859 Ų595%0.05233%0.326CS..  trans-55.6127.6177.4-30.239000112.5Y161 P202 Y204 I209 Q212Y161-P511 HydrophobicContact CE1-CG 4.18Å; P202-P511 HydrophobicContact CB-CB 4.23Å; P202-P511 HydrophobicContact CG-CB 3.76Å; P202-P511 HydrophobicContact CG-CG 4.17Å; Y204-P511 HydrophobicContact CE2-CB 4.38Å; Y204-P511 WeakPolarHBondContact OH-CB 3.36Å; I209-P511 HydrophobicContact CD1-CB 4.04Å; Q212-P511 PolarHBondContact NE2-O 3.04Å
512C96.1Very high94.2Very high45 Ų4560.4 Ų60.430%0.30434%0.335SS..  trans-140.3115.8-177.8-162.80000111.6T510 N514 P515 C520T510-C512 PolarHBondContact O-N 3.13Å; C512-N514 VanDerWaalsContact SG-C 3.59Å; C512-P515 WeakPolarHBondContact SG-CA 3.36Å; C512-C520 HydrophobicContact CB-CB 3.77Å; C512-C520 WeakPolarHBondContact CB-SG 3.48Å; C512-C520 WeakPolarHBondContact SG-CB 3.41Å; C512-C520 CovalentContact SG-SG 2.04Å; C512-C520 PolarHBondContact SG-SG 3.1Å
513C95.7Very high93.4Very high47 Ų4764.9 Ų64.932%0.31835%0.354SS..SBendtrans-72.6-42.3177.6-161.70000111.4I209 Q212 C520 C522I209-C513 HydrophobicContact CG2-CB 4.07Å; Q212-C513 HydrophobicContact CB-CB 4.16Å; Q212-C513 VanDerWaalsContact OE1-CB 3.24Å; C513-C520 WeakPolarHBondContact CB-O 3.04Å; C513-C520 PolarHBondContact N-O 3.03Å; C513-C522 HydrophobicContact CB-CB 3.93Å; C513-C522 WeakPolarHBondContact CB-SG 3.29Å; C513-C522 WeakPolarHBondContact SG-CA 3.03Å; C513-C522 WeakPolarHBondContact SG-CB 3.16Å; C513-C522 CovalentContact SG-SG 2.03Å; C513-C522 PolarHBondContact SG-SG 2.9Å
514N94.1Very high91.8Very high46 Ų4665.9 Ų65.925%0.24637%0.372CS..  trans-141.6109.8173-170.7-19.1000111.1C512 Y516 Q517 C520 R521C512-N514 VanDerWaalsContact SG-C 3.59Å; N514-Y516 PolarHBondContact O-N 2.93Å; N514-Y516 WeakPolarHBondContact OD1-CB 2.97Å; N514-Y516 WeakPolarHBondContact OD1-CD2 3.42Å; N514-Y516 PolarHBondContact OD1-N 3.19Å; N514-Q517 HydrophobicContact CB-CB 4.25Å; N514-Q517 HydrophobicContact CB-CG 3.88Å; N514-Q517 PolarHBondContact O-N 3.17Å; N514-Q517 VanDerWaalsContact O-N 3.16Å; N514-C520 WeakPolarHBondContact O-CA 3.35Å; N514-R521 VanDerWaalsContact CB-O 3.24Å; N514-R521 WeakPolarHBondContact CB-O 3.4Å
515P91.9Very high89.8Confident100 Ų10068 Ų6865%0.64939%0.387SS*.THydrogen-bonded Turntrans-69.9-10.9-178.429.8-36000114C512C512-P515 WeakPolarHBondContact SG-CA 3.36Å
516Y90.8Very high89.5Confident208 Ų20865.1 Ų65.182%0.81638%0.377SS*.THydrogen-bonded Turntrans-90.9-2.6176.1-54.3-69.9000113.2N514N514-Y516 PolarHBondContact O-N 2.93Å; N514-Y516 WeakPolarHBondContact OD1-CB 2.97Å; N514-Y516 WeakPolarHBondContact OD1-CD2 3.42Å; N514-Y516 PolarHBondContact OD1-N 3.19Å
517Q90Very high89.1Confident63 Ų6364.9 Ų64.929%0.29438%0.378SS..SBendtrans-106140.3177.6-64.7-68.2-41.400109.8N514 A519 C520 R521N514-Q517 HydrophobicContact CB-CB 4.25Å; N514-Q517 HydrophobicContact CB-CG 3.88Å; N514-Q517 PolarHBondContact O-N 3.17Å; N514-Q517 VanDerWaalsContact O-N 3.16Å; Q517-A519 PolarHBondContact O-N 2.92Å; Q517-C520 PolarHBondContact O-N 3.24Å; Q517-R521 HydrophobicContact CB-CB 4.22Å
518T89.7Confident88.9Confident40 Ų4063.1 Ų63.125%0.24536%0.364CS..G310 helixtrans-52.1136.2171.5-440000109.6P182 D185 C520 R521P182-T518 HydrophobicContact CB-CG2 4.06Å; P182-T518 HydrophobicContact CG-CG2 3.92Å; D185-T518 PolarHBondContact OD1-OG1 2.63Å; T518-C520 PolarHBondContact O-N 3.21Å; T518-C520 VanDerWaalsContact O-N 3.14Å; T518-R521 VanDerWaalsContact O-CD 3.3Å; T518-R521 WeakPolarHBondContact O-CD 3.15Å; T518-R521 WeakPolarHBondContact O-CG 3.1Å
519A90.7Very high88.6Confident8 Ų861.3 Ų61.37%0.06635%0.347CS..G310 helixtrans56.823-177.700000115.5P182 D198 A200 Q517 R521P182-A519 HydrophobicContact CG-CB 4.15Å; D198-A519 WeakPolarHBondContact O-CA 3.45Å; A200-A519 HydrophobicContact CB-CB 4.26Å; A200-A519 WeakPolarHBondContact CB-O 3.31Å; A200-A519 PolarHBondContact N-O 2.82Å; Q517-A519 PolarHBondContact O-N 2.92Å; A519-R521 VanDerWaalsContact C-N 3.31Å; A519-R521 PolarHBondContact O-N 2.65Å
520C94Very high88.1Confident25 Ų2564.2 Ų64.217%0.16936%0.363CS..G310 helixtrans63.428.9174.4-770000115.6V199 Q212 C512 C513 N514 Q517 T518V199-C520 HydrophobicContact CG2-CB 4.17Å; Q212-C520 PolarHBondContact OE1-O 3.37Å; C512-C520 HydrophobicContact CB-CB 3.77Å; C512-C520 WeakPolarHBondContact CB-SG 3.48Å; C512-C520 WeakPolarHBondContact SG-CB 3.41Å; C512-C520 CovalentContact SG-SG 2.04Å; C512-C520 PolarHBondContact SG-SG 3.1Å; C513-C520 WeakPolarHBondContact CB-O 3.04Å; C513-C520 PolarHBondContact N-O 3.03Å; N514-C520 WeakPolarHBondContact O-CA 3.35Å; Q517-C520 PolarHBondContact O-N 3.24Å; T518-C520 PolarHBondContact O-N 3.21Å; T518-C520 VanDerWaalsContact O-N 3.14Å
521R93.4Very high87.6Confident14 Ų1466.5 Ų66.55%0.05337%0.374CS..  trans-64.7141.7-174.7-61.1168121.8-87.2-5.9112.9D169 Q212 N514 Q517 T518 A519 Q523D169-R521 IonicContact OD1-CZ 2.6Å; D169-R521 IonicContact OD1-NH2 3.91Å; D169-R521 PolarHBondContact OD1-NH2 3.15Å; D169-R521 IonicContact OD2-CZ 2.65Å; D169-R521 IonicContact OD2-NH2 3.78Å; D169-R521 PolarHBondContact OD2-NH2 3.45Å; Q212-R521 CarbonylContact O-C 3.57Å; Q212-R521 VanDerWaalsContact O-CA 3.28Å; Q212-R521 WeakPolarHBondContact O-CA 3.43Å; N514-R521 VanDerWaalsContact CB-O 3.24Å; N514-R521 WeakPolarHBondContact CB-O 3.4Å; Q517-R521 HydrophobicContact CB-CB 4.22Å; T518-R521 VanDerWaalsContact O-CD 3.3Å; T518-R521 WeakPolarHBondContact O-CD 3.15Å; T518-R521 WeakPolarHBondContact O-CG 3.1Å; A519-R521 VanDerWaalsContact C-N 3.31Å; A519-R521 PolarHBondContact O-N 2.65Å; R521-Q523 PolarHBondContact NH1-O 2.84Å
522C92.6Very high87Confident40 Ų4070.6 Ų70.627%0.2740%0.397SS..SBendtrans-71.2-33.4175-69.20000113.5Q212 C513Q212-C522 PolarHBondContact O-N 2.83Å; C513-C522 HydrophobicContact CB-CB 3.93Å; C513-C522 WeakPolarHBondContact CB-SG 3.29Å; C513-C522 WeakPolarHBondContact SG-CA 3.03Å; C513-C522 WeakPolarHBondContact SG-CB 3.16Å; C513-C522 CovalentContact SG-SG 2.03Å; C513-C522 PolarHBondContact SG-SG 2.9Å
523Q80.7Confident86.3Confident156 Ų15672.6 Ų72.673%0.72941%0.405SS*.SBendtrans-124146-179.3-64.9-178.9-600109.4R521R521-Q523 PolarHBondContact NH1-O 2.84Å
524A62Low85.5Confident71 Ų7174.8 Ų74.859%0.58741%0.412SS*.  trans-61.2146.4170.500000109.5
525P56.6Low84.8Confident126 Ų12677.4 Ų77.482%0.81843%0.427SS*.  trans-46.90-178.4-30.235.8000116.3Q183Q183-P525 HydrophobicContact CB-CG 4.45Å; Q183-P525 VanDerWaalsContact OE1-CG 3.24Å

Retrieved 525 of 525 residues in 120.9 ms (Link to these results)