A0A096NV02_PAPAN Loading...

Prostaglandin E2 receptor EP2 subtype

Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.

AlphaFold DB , UniProt , Accession A0A096NV02, Species PAPAN (Papio anubis, Olive baboon), Gene PTGER2, Length 358 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	36	Very low	36.9	Very low	249 Å²	249	142.6 Å²	142.6	100%	1.227	81%	0.814	S	S	*	*				0	91.9	0	-78.7	161.3	150.2	0	0	107.4
2	G	32	Very low	39.3	Very low	81 Å²	81	141 Å²	141	84%	0.835	80%	0.801	S	S	*	*			trans	-83.9	122.6	177.3	0	0	0	0	0	109.2	A4	G2-A4 PolarHBondContact O-N 3.35Å
3	N	35.5	Very low	42	Very low	170 Å²	170	130.8 Å²	130.8	91%	0.909	74%	0.744	S	S	*	*			trans	-83.5	109.6	171.5	-120.4	10.5	0	0	0	107.5	S5	N3-S5 PolarHBondContact O-N 2.94Å
4	A	35.4	Very low	44.2	Very low	90 Å²	90	128.5 Å²	128.5	74%	0.744	72%	0.723	S	S	*	*			trans	-62.7	118.1	174.2	0	0	0	0	0	109.5	G2 N6	G2-A4 PolarHBondContact O-N 3.35Å; A4-N6 PolarHBondContact O-N 2.89Å
5	S	38.9	Very low	46.3	Very low	88 Å²	88	126.7 Å²	126.7	62%	0.615	72%	0.717	S	S	*	*			trans	-61.6	117.5	158.1	39.1	0	0	0	0	107.8	N3 D7	N3-S5 PolarHBondContact O-N 2.94Å; S5-D7 PolarHBondContact O-N 3.42Å; S5-D7 PolarHBondContact OG-OD2 3.43Å
6	N	35.2	Very low	48.6	Very low	162 Å²	162	124.1 Å²	124.1	87%	0.866	69%	0.692	S	S	*	*			trans	-66.9	76.7	163.8	-104.1	1.1	0	0	0	108	A4 S8	A4-N6 PolarHBondContact O-N 2.89Å; N6-S8 PolarHBondContact O-N 3.22Å
7	D	33	Very low	50.7	Low	131 Å²	131	123.4 Å²	123.4	70%	0.701	68%	0.682	S	S	*	*			trans	-74	83.2	163.6	-73.2	-43.7	0	0	0	107	S5 W9	S5-D7 PolarHBondContact O-N 3.42Å; S5-D7 PolarHBondContact OG-OD2 3.43Å; D7-W9 PolarHBondContact O-N 3.32Å
8	S	34.8	Very low	52.5	Low	108 Å²	108	124.8 Å²	124.8	76%	0.755	68%	0.675	S	S	*	*			trans	-56.4	111.6	165.2	52.5	0	0	0	0	107.9	N6	N6-S8 PolarHBondContact O-N 3.22Å
9	W	32.2	Very low	54	Low	231 Å²	231	119.3 Å²	119.3	88%	0.875	65%	0.646	S	S	*	*			trans	-36.4	135.8	168.7	-63.8	84.5	0	0	0	111.2	D7 E11	D7-W9 PolarHBondContact O-N 3.32Å; W9-E11 PolarHBondContact O-N 3.01Å
10	P	43.1	Very low	55.3	Low	117 Å²	117	114.9 Å²	114.9	76%	0.76	62%	0.623	S	S	*	*			trans	-61.9	112.7	174.1	25.4	-29.4	0	0	0	107.4	D12	P10-D12 PolarHBondContact O-N 3.46Å; P10-D12 VanDerWaalsContact O-N 3.15Å
11	E	49.3	Very low	56	Low	142 Å²	142	115.8 Å²	115.8	66%	0.664	64%	0.635	S	S	*	*			trans	-53.8	123.1	171.7	-68.5	-163.4	138.1	0	0	108.7	W9 C13	W9-E11 PolarHBondContact O-N 3.01Å; E11-C13 PolarHBondContact O-N 2.96Å; E11-C13 VanDerWaalsContact O-N 3.1Å
12	D	66.6	Low	57.7	Low	123 Å²	123	107.9 Å²	107.9	66%	0.658	62%	0.617	S	S	*	*			trans	-54.5	117.9	178.8	-92.2	-35.3	0	0	0	109.6	P10 E14 T15	P10-D12 PolarHBondContact O-N 3.46Å; P10-D12 VanDerWaalsContact O-N 3.15Å; D12-E14 PolarHBondContact O-N 3.21Å; D12-T15 PolarHBondContact O-N 2.89Å; D12-T15 PolarHBondContact O-OG1 2.97Å
13	C	74	Confident	59.9	Low	9 Å²	9	108.2 Å²	108.2	6%	0.061	60%	0.597	C	S	.	*	T	Hydrogen-bonded Turn	trans	-56.2	-25.6	-175.7	-167.3	0	0	0	0	113.5	E11 T15 R16 Q180 C182	E11-C13 PolarHBondContact O-N 2.96Å; E11-C13 VanDerWaalsContact O-N 3.1Å; C13-T15 PolarHBondContact O-N 3.06Å; C13-R16 PolarHBondContact O-N 3.16Å; C13-Q180 PolarHBondContact O-NE2 2.97Å; C13-C182 HydrophobicContact CB-CB 4.05Å; C13-C182 WeakPolarHBondContact CB-SG 3.43Å; C13-C182 WeakPolarHBondContact SG-CA 3.38Å; C13-C182 WeakPolarHBondContact SG-CB 3.5Å; C13-C182 PolarHBondContact SG-N 3.42Å; C13-C182 VanDerWaalsContact SG-N 3.42Å; C13-C182 CovalentContact SG-SG 2.02Å; C13-C182 PolarHBondContact SG-SG 3.02Å
14	E	73.3	Confident	62.1	Low	98 Å²	98	103 Å²	103	46%	0.458	57%	0.574	S	S	.	*	T	Hydrogen-bonded Turn	trans	-62	-29.1	176.8	-60.9	-162.5	167.2	0	0	113.2	D12	D12-E14 PolarHBondContact O-N 3.21Å
15	T	75.5	Confident	64.5	Low	102 Å²	102	101.6 Å²	101.6	63%	0.626	56%	0.557	S	S	*	*	T	Hydrogen-bonded Turn	trans	-103.2	-7.1	-175.9	61.7	0	0	0	0	113.7	D12 C13 Q17	D12-T15 PolarHBondContact O-N 2.89Å; D12-T15 PolarHBondContact O-OG1 2.97Å; C13-T15 PolarHBondContact O-N 3.06Å; T15-Q17 PolarHBondContact O-N 2.97Å
16	R	82.2	Confident	66.8	Low	85 Å²	85	99.8 Å²	99.8	32%	0.321	55%	0.548	S	S	.	.			trans	-68.3	131.5	-174.5	-156.6	176.6	-152.8	174.6	3.8	111.6	C13 T98 Q180	C13-R16 PolarHBondContact O-N 3.16Å; R16-T98 WeakPolarHBondContact O-CB 3.29Å; R16-T98 VanDerWaalsContact O-CG2 3.23Å; R16-T98 WeakPolarHBondContact O-CG2 3.5Å; R16-T98 PolarHBondContact O-OG1 3.3Å; R16-Q180 PolarHBondContact O-NE2 3.1Å
17	Q	84.3	Confident	69	Low	111 Å²	111	96.2 Å²	96.2	52%	0.519	53%	0.528	S	S	.	.			trans	-100.7	-15.3	-177.1	-66.6	-174.3	-10.9	0	0	114.1	T15 Q97 T98 A101	T15-Q17 PolarHBondContact O-N 2.97Å; Q17-Q97 WeakPolarHBondContact O-CA 3.45Å; Q17-T98 WeakPolarHBondContact CA-OG1 3.43Å; Q17-T98 PolarHBondContact O-N 3.41Å; Q17-T98 PolarHBondContact O-OG1 3.26Å; Q17-A101 HydrophobicContact CB-CB 3.78Å; Q17-A101 HydrophobicContact CG-CB 4.12Å; Q17-A101 VanDerWaalsContact O-CB 3.3Å; Q17-A101 WeakPolarHBondContact O-CB 3.18Å
18	W	83.2	Confident	71.4	Confident	149 Å²	149	90.4 Å²	90.4	56%	0.564	50%	0.498	S	S	*	.	B	Isolated β-bridge	trans	-123.3	144.4	-174.4	-55.2	97.2	0	0	0	111.3	Q97	W18-Q97 HydrophobicContact CE3-CG 4.13Å; W18-Q97 HydrophobicContact CZ3-CG 3.9Å
19	L	82.1	Confident	73.9	Confident	21 Å²	21	87.4 Å²	87.4	11%	0.11	48%	0.476	C	S	.	.	P	Polyproline II helix	trans	-71.5	144.8	174.7	-85.3	102	0	0	0	111.6	E23 Y93 N96 Q97 T185	L19-E23 HydrophobicContact CD2-CB 4.05Å; L19-Y93 HydrophobicContact CD2-CD1 3.74Å; L19-Y93 HydrophobicContact CD2-CE1 3.65Å; L19-N96 VanDerWaalsContact CD1-C 3.45Å; L19-N96 PolarHBondContact N-O 3.27Å; L19-N96 VanDerWaalsContact N-O 3.14Å; L19-Q97 VanDerWaalsContact CD1-C 3.48Å; L19-Q97 VanDerWaalsContact CD1-O 3.23Å; L19-Q97 WeakPolarHBondContact CD1-O 3.36Å; L19-T185 HydrophobicContact CD1-CG2 4.36Å; L19-T185 HydrophobicContact CD2-CG2 3.63Å; L19-T185 HydrophobicContact CG-CG2 4.28Å
20	P	79.3	Confident	76.5	Confident	31 Å²	31	81 Å²	81	20%	0.201	46%	0.463	C	S	.	.	P	Polyproline II helix	trans	-58.6	141.8	169.7	-16.5	26.5	0	0	0	111.9	G22 E23 P183	P20-G22 PolarHBondContact O-N 3.35Å; P20-E23 HydrophobicContact CB-CG 4.17Å; P20-E23 HydrophobicContact CG-CG 4.18Å; P20-E23 PolarHBondContact O-N 3.11Å; P20-P183 HydrophobicContact CG-CB 4.34Å
21	P	70.2	Confident	78.5	Confident	133 Å²	133	76.9 Å²	76.9	86%	0.864	43%	0.433	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.8	130.7	176.3	26	-32.7	0	0	0	110.7
22	G	71.9	Confident	80.3	Confident	83 Å²	83	72.7 Å²	72.7	86%	0.856	41%	0.413	S	S	*	.	T	Hydrogen-bonded Turn	trans	99.9	-3	179.5	0	0	0	0	0	115.6	P20 S24	P20-G22 PolarHBondContact O-N 3.35Å; G22-S24 PolarHBondContact O-N 3.37Å
23	E	78.1	Confident	81.3	Confident	88 Å²	88	70.2 Å²	70.2	41%	0.411	41%	0.405	S	S	.	.			trans	-69.2	122.3	173	-77.2	-64.4	153.5	0	0	111.3	L19 P20 Y93 P183	L19-E23 HydrophobicContact CD2-CB 4.05Å; P20-E23 HydrophobicContact CB-CG 4.17Å; P20-E23 HydrophobicContact CG-CG 4.18Å; P20-E23 PolarHBondContact O-N 3.11Å; E23-Y93 HydrophobicContact CB-CE1 4.25Å; E23-P183 HydrophobicContact CG-CB 4.05Å
24	S	82.2	Confident	81.8	Confident	62 Å²	62	71.1 Å²	71.1	43%	0.434	41%	0.414	S	S	.	.			trans	-99.2	139.7	-176.2	75.3	0	0	0	0	112.2	G22 A26	G22-S24 PolarHBondContact O-N 3.37Å; S24-A26 PolarHBondContact O-N 2.97Å
25	P	85.9	Confident	82.4	Confident	60 Å²	60	66.5 Å²	66.5	39%	0.39	39%	0.392	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75	-0.3	174.1	30.8	-35.3	0	0	0	113.2	I27 S28 S29 Y93	P25-I27 PolarHBondContact O-N 3.47Å; P25-S28 PolarHBondContact O-N 3.48Å; P25-S28 VanDerWaalsContact O-N 3.16Å; P25-S29 PolarHBondContact O-N 3.49Å; P25-S29 PolarHBondContact O-OG 2.92Å; P25-Y93 HydrophobicContact CB-CD1 4.12Å; P25-Y93 HydrophobicContact CB-CD2 4.03Å; P25-Y93 HydrophobicContact CB-CG 3.78Å
26	A	86.4	Confident	83	Confident	50 Å²	50	63 Å²	63	41%	0.413	37%	0.371	S	S	.	.	H	α-helix	trans	-58.1	-42.4	-167.9	0	0	0	0	0	113.5	S24 S29 V30	S24-A26 PolarHBondContact O-N 2.97Å; A26-S29 WeakPolarHBondContact CA-OG 3.49Å; A26-S29 PolarHBondContact O-OG 3.44Å; A26-V30 WeakPolarHBondContact O-CB 3.47Å; A26-V30 WeakPolarHBondContact O-CG2 3.31Å; A26-V30 PolarHBondContact O-N 3.2Å
27	I	82.4	Confident	83.3	Confident	86 Å²	86	63.6 Å²	63.6	44%	0.441	38%	0.38	S	S	.	.	H	α-helix	trans	-65.4	-47.3	179	-63.3	170.6	0	0	0	110	P25 S29 V30 M31	P25-I27 PolarHBondContact O-N 3.47Å; I27-S29 PolarHBondContact O-N 2.89Å; I27-V30 PolarHBondContact O-N 2.83Å; I27-M31 HydrophobicContact CG2-CG 4.49Å; I27-M31 HydrophobicContact CG2-SD 3.93Å; I27-M31 WeakPolarHBondContact O-CB 3.49Å; I27-M31 VanDerWaalsContact O-CG 3.26Å; I27-M31 WeakPolarHBondContact O-CG 3.32Å; I27-M31 PolarHBondContact O-N 2.87Å
28	S	82.6	Confident	83.2	Confident	10 Å²	10	58.3 Å²	58.3	7%	0.07	36%	0.355	C	S	.	.	H	α-helix	trans	-65.6	-37.9	-179.4	-56.5	0	0	0	0	112.4	P25 F32	P25-S28 PolarHBondContact O-N 3.48Å; P25-S28 VanDerWaalsContact O-N 3.16Å; S28-F32 WeakPolarHBondContact O-CB 3.45Å; S28-F32 PolarHBondContact O-N 3.07Å
29	S	86.7	Confident	83.4	Confident	44 Å²	44	51.2 Å²	51.2	31%	0.308	33%	0.328	S	S	.	.	H	α-helix	trans	-70.2	-38.5	177.3	67.8	0	0	0	0	112.3	P25 A26 I27 S33	P25-S29 PolarHBondContact O-N 3.49Å; P25-S29 PolarHBondContact O-OG 2.92Å; A26-S29 WeakPolarHBondContact CA-OG 3.49Å; A26-S29 PolarHBondContact O-OG 3.44Å; I27-S29 PolarHBondContact O-N 2.89Å; S29-S33 WeakPolarHBondContact O-CB 3.3Å; S29-S33 PolarHBondContact O-N 3.39Å; S29-S33 PolarHBondContact O-OG 3.17Å
30	V	87.3	Confident	83.6	Confident	97 Å²	97	54.5 Å²	54.5	59%	0.588	35%	0.345	S	S	*	.	H	α-helix	trans	-64.6	-46.9	173.2	169.6	0	0	0	0	110.4	A26 I27 F32 S33 A34	A26-V30 WeakPolarHBondContact O-CB 3.47Å; A26-V30 WeakPolarHBondContact O-CG2 3.31Å; A26-V30 PolarHBondContact O-N 3.2Å; I27-V30 PolarHBondContact O-N 2.83Å; V30-F32 VanDerWaalsContact C-N 3.35Å; V30-F32 PolarHBondContact O-N 3.28Å; V30-S33 PolarHBondContact O-N 3.37Å; V30-A34 VanDerWaalsContact O-CB 3.22Å; V30-A34 WeakPolarHBondContact O-CB 3.46Å; V30-A34 PolarHBondContact O-N 3.16Å
31	M	84.5	Confident	83.9	Confident	30 Å²	30	56 Å²	56	15%	0.148	35%	0.351	C	S	.	.	H	α-helix	trans	-58.5	-46.4	176.9	-74.3	176.8	71.5	0	0	111.7	I27 G35 S305 I306 I309	I27-M31 HydrophobicContact CG2-CG 4.49Å; I27-M31 HydrophobicContact CG2-SD 3.93Å; I27-M31 WeakPolarHBondContact O-CB 3.49Å; I27-M31 VanDerWaalsContact O-CG 3.26Å; I27-M31 WeakPolarHBondContact O-CG 3.32Å; I27-M31 PolarHBondContact O-N 2.87Å; M31-G35 PolarHBondContact O-N 3.25Å; M31-S305 VanDerWaalsContact CE-OG 3.29Å; M31-S305 WeakPolarHBondContact CE-OG 3.24Å; M31-I306 HydrophobicContact CE-CG1 3.86Å; M31-I309 HydrophobicContact CB-CD1 3.74Å; M31-I309 HydrophobicContact CE-CD1 3.94Å; M31-I309 HydrophobicContact CG-CD1 4.08Å; M31-I309 WeakPolarHBondContact O-CD1 3.34Å
32	F	87.1	Confident	84.5	Confident	55 Å²	55	49.6 Å²	49.6	24%	0.241	31%	0.31	C	S	.	.	H	α-helix	trans	-60.5	-51.2	176.2	176.4	-115.2	0	0	0	112.2	S28 V30 A34 G35 V36 T82 P87 L90	S28-F32 WeakPolarHBondContact O-CB 3.45Å; S28-F32 PolarHBondContact O-N 3.07Å; V30-F32 VanDerWaalsContact C-N 3.35Å; V30-F32 PolarHBondContact O-N 3.28Å; F32-A34 PolarHBondContact O-N 2.87Å; F32-G35 PolarHBondContact O-N 3.45Å; F32-V36 HydrophobicContact CD2-CG2 3.89Å; F32-V36 HydrophobicContact CE1-CG2 4.44Å; F32-V36 HydrophobicContact CE2-CG2 3.51Å; F32-V36 HydrophobicContact CZ-CG2 3.82Å; F32-V36 WeakPolarHBondContact O-CG2 3.34Å; F32-V36 PolarHBondContact O-N 2.93Å; F32-T82 HydrophobicContact CD2-CG2 3.79Å; F32-T82 HydrophobicContact CE2-CG2 4.26Å; F32-P87 HydrophobicContact CE2-CG 4.44Å; F32-L90 HydrophobicContact CD1-CD1 4.16Å; F32-L90 HydrophobicContact CG-CD1 4.41Å
33	S	87.9	Confident	85	Confident	70 Å²	70	47.7 Å²	47.7	49%	0.49	28%	0.279	S	S	.	.	H	α-helix	trans	-63	-43.9	-177.2	-55.1	0	0	0	0	111.4	S29 V30 L37	S29-S33 WeakPolarHBondContact O-CB 3.3Å; S29-S33 PolarHBondContact O-N 3.39Å; S29-S33 PolarHBondContact O-OG 3.17Å; V30-S33 PolarHBondContact O-N 3.37Å; S33-L37 WeakPolarHBondContact O-CB 3.41Å; S33-L37 PolarHBondContact O-N 3.46Å
34	A	85.4	Confident	85.2	Confident	29 Å²	29	45.6 Å²	45.6	24%	0.24	28%	0.277	C	S	.	.	H	α-helix	trans	-65.6	-40.5	177.1	0	0	0	0	0	112	V30 F32 G38 I309 W313	V30-A34 VanDerWaalsContact O-CB 3.22Å; V30-A34 WeakPolarHBondContact O-CB 3.46Å; V30-A34 PolarHBondContact O-N 3.16Å; F32-A34 PolarHBondContact O-N 2.87Å; A34-G38 PolarHBondContact O-N 3.28Å; A34-I309 HydrophobicContact CB-CG2 4.1Å; A34-W313 PolarHBondContact O-NE1 3.04Å
35	G	84.9	Confident	85	Confident	0 Å²	0	44.6 Å²	44.6	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-64.2	-51.5	177.1	0	0	0	0	0	112.2	M31 F32 N39	M31-G35 PolarHBondContact O-N 3.25Å; F32-G35 PolarHBondContact O-N 3.45Å; G35-N39 WeakPolarHBondContact O-CB 3.44Å; G35-N39 PolarHBondContact O-N 2.9Å; G35-N39 PolarHBondContact O-ND2 3.32Å
36	V	88.9	Confident	84.5	Confident	30 Å²	30	41.9 Å²	41.9	18%	0.182	25%	0.249	C	C	.	.	H	α-helix	trans	-63	-48.9	179.2	173.2	0	0	0	0	110.9	F32 G38 N39 L40 L79 T82	F32-V36 HydrophobicContact CD2-CG2 3.89Å; F32-V36 HydrophobicContact CE1-CG2 4.44Å; F32-V36 HydrophobicContact CE2-CG2 3.51Å; F32-V36 HydrophobicContact CZ-CG2 3.82Å; F32-V36 WeakPolarHBondContact O-CG2 3.34Å; F32-V36 PolarHBondContact O-N 2.93Å; V36-G38 PolarHBondContact O-N 3.44Å; V36-N39 PolarHBondContact O-N 3.42Å; V36-L40 HydrophobicContact CG1-CD1 3.68Å; V36-L40 HydrophobicContact CG1-CG 4.19Å; V36-L40 WeakPolarHBondContact O-CB 3.32Å; V36-L40 VanDerWaalsContact O-CG 3.24Å; V36-L40 WeakPolarHBondContact O-CG 3.28Å; V36-L40 PolarHBondContact O-N 3Å; V36-L79 HydrophobicContact CG1-CD1 4.47Å; V36-L79 HydrophobicContact CG2-CD1 4.49Å; V36-T82 HydrophobicContact CG2-CG2 3.9Å
37	L	87.9	Confident	84.2	Confident	96 Å²	96	41.3 Å²	41.3	50%	0.503	25%	0.245	S	C	.	.	H	α-helix	trans	-62.1	-46.6	-178.7	-176.8	62.8	0	0	0	111.6	S33 L40 I41 W313	S33-L37 WeakPolarHBondContact O-CB 3.41Å; S33-L37 PolarHBondContact O-N 3.46Å; L37-L40 PolarHBondContact O-N 3.13Å; L37-I41 HydrophobicContact CD1-CD1 3.89Å; L37-I41 HydrophobicContact CD1-CG1 4.26Å; L37-I41 HydrophobicContact CG-CD1 3.8Å; L37-I41 WeakPolarHBondContact O-CB 3.34Å; L37-I41 WeakPolarHBondContact O-CG1 3.45Å; L37-I41 PolarHBondContact O-N 3.16Å; L37-W313 HydrophobicContact CB-CZ2 4.42Å; L37-W313 HydrophobicContact CD2-CH2 4.16Å; L37-W313 HydrophobicContact CD2-CZ2 4.41Å; L37-W313 HydrophobicContact CG-CH2 4.28Å; L37-W313 HydrophobicContact CG-CZ2 4.39Å
38	G	83.4	Confident	83.9	Confident	0 Å²	0	45.5 Å²	45.5	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-60.2	-47.6	179	0	0	0	0	0	112.3	A34 V36 I41 A42	A34-G38 PolarHBondContact O-N 3.28Å; V36-G38 PolarHBondContact O-N 3.44Å; G38-I41 PolarHBondContact O-N 3.07Å; G38-A42 WeakPolarHBondContact O-CB 3.48Å; G38-A42 PolarHBondContact O-N 3.35Å
39	N	86.2	Confident	83.4	Confident	0 Å²	0	49.2 Å²	49.2	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-64.3	-44.5	178.2	-81.4	-65.2	0	0	0	112.7	G35 V36 I41 A42 L43 V75 L79 P312	G35-N39 WeakPolarHBondContact O-CB 3.44Å; G35-N39 PolarHBondContact O-N 2.9Å; G35-N39 PolarHBondContact O-ND2 3.32Å; V36-N39 PolarHBondContact O-N 3.42Å; N39-I41 PolarHBondContact O-N 3.28Å; N39-A42 PolarHBondContact O-N 3.45Å; N39-L43 WeakPolarHBondContact O-CG 3.29Å; N39-L43 PolarHBondContact O-N 3.34Å; N39-V75 HydrophobicContact CB-CG1 4.08Å; N39-V75 WeakPolarHBondContact O-CG1 3.08Å; N39-V75 VanDerWaalsContact OD1-CG1 3.32Å; N39-V75 WeakPolarHBondContact OD1-CG1 3.22Å; N39-V75 PolarHBondContact OD1-O 3.42Å; N39-V75 VanDerWaalsContact OD1-O 3.07Å; N39-L79 HydrophobicContact CB-CB 3.9Å; N39-L79 HydrophobicContact CB-CD1 3.9Å; N39-L79 HydrophobicContact CB-CG 4.37Å; N39-P312 HydrophobicContact CB-CG 4.45Å; N39-P312 VanDerWaalsContact CG-CG 3.42Å; N39-P312 WeakPolarHBondContact OD1-CG 3.31Å
40	L	87.5	Confident	82.5	Confident	90 Å²	90	51.6 Å²	51.6	47%	0.471	27%	0.269	S	S	.	.	H	α-helix	trans	-63.8	-41	177.7	-71.7	178	0	0	0	112.1	V36 L37 L43 A44 L79	V36-L40 HydrophobicContact CG1-CD1 3.68Å; V36-L40 HydrophobicContact CG1-CG 4.19Å; V36-L40 WeakPolarHBondContact O-CB 3.32Å; V36-L40 VanDerWaalsContact O-CG 3.24Å; V36-L40 WeakPolarHBondContact O-CG 3.28Å; V36-L40 PolarHBondContact O-N 3Å; L37-L40 PolarHBondContact O-N 3.13Å; L40-L43 PolarHBondContact O-N 3.34Å; L40-A44 VanDerWaalsContact O-CB 3.3Å; L40-A44 WeakPolarHBondContact O-CB 3.47Å; L40-A44 PolarHBondContact O-N 3.04Å; L40-L79 HydrophobicContact CD2-CD2 4.09Å
41	I	85.3	Confident	81.7	Confident	62 Å²	62	55.3 Å²	55.3	32%	0.318	27%	0.273	S	S	.	.	H	α-helix	trans	-61.2	-47.8	174.1	-70.6	168.9	0	0	0	109.9	L37 G38 N39 L43 A44 L45 W313 A316	L37-I41 HydrophobicContact CD1-CD1 3.89Å; L37-I41 HydrophobicContact CD1-CG1 4.26Å; L37-I41 HydrophobicContact CG-CD1 3.8Å; L37-I41 WeakPolarHBondContact O-CB 3.34Å; L37-I41 WeakPolarHBondContact O-CG1 3.45Å; L37-I41 PolarHBondContact O-N 3.16Å; G38-I41 PolarHBondContact O-N 3.07Å; N39-I41 PolarHBondContact O-N 3.28Å; I41-L43 PolarHBondContact O-N 3.23Å; I41-A44 PolarHBondContact O-N 3.21Å; I41-L45 HydrophobicContact CG2-CD1 3.8Å; I41-L45 HydrophobicContact CG2-CG 4.19Å; I41-L45 VanDerWaalsContact O-CB 3.23Å; I41-L45 WeakPolarHBondContact O-CB 3.36Å; I41-L45 WeakPolarHBondContact O-CG 3.42Å; I41-L45 PolarHBondContact O-N 3.37Å; I41-W313 HydrophobicContact CD1-CH2 4.28Å; I41-W313 HydrophobicContact CD1-CZ3 4.46Å; I41-A316 HydrophobicContact CG2-CB 4.11Å
42	A	82	Confident	80.8	Confident	0 Å²	0	55.8 Å²	55.8	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-60.3	-44.9	179.4	0	0	0	0	0	112.1	G38 N39 L45 L46 V75 P312 F315	G38-A42 WeakPolarHBondContact O-CB 3.48Å; G38-A42 PolarHBondContact O-N 3.35Å; N39-A42 PolarHBondContact O-N 3.45Å; A42-L45 PolarHBondContact O-N 3.33Å; A42-L46 WeakPolarHBondContact O-CB 3.36Å; A42-L46 WeakPolarHBondContact O-CG 3.49Å; A42-L46 PolarHBondContact O-N 3.3Å; A42-V75 HydrophobicContact CB-CG1 3.81Å; A42-V75 HydrophobicContact CB-CG2 4.1Å; A42-P312 HydrophobicContact CB-CB 4.13Å; A42-F315 HydrophobicContact CB-CD1 4.23Å
43	L	83.2	Confident	79.5	Confident	42 Å²	42	56.6 Å²	56.6	22%	0.22	29%	0.293	C	S	.	.	H	α-helix	trans	-62.6	-45.8	174.6	-73.7	175.4	0	0	0	112.3	N39 L40 I41 L45 L46 A47 T72 V75 L79	N39-L43 WeakPolarHBondContact O-CG 3.29Å; N39-L43 PolarHBondContact O-N 3.34Å; L40-L43 PolarHBondContact O-N 3.34Å; I41-L43 PolarHBondContact O-N 3.23Å; L43-L45 VanDerWaalsContact C-N 3.29Å; L43-L45 PolarHBondContact O-N 3.24Å; L43-L46 PolarHBondContact O-N 3.04Å; L43-A47 VanDerWaalsContact O-CB 3.31Å; L43-A47 WeakPolarHBondContact O-CB 3.32Å; L43-A47 PolarHBondContact O-N 2.88Å; L43-T72 HydrophobicContact CD2-CG2 4.31Å; L43-V75 HydrophobicContact CD1-CG1 4.45Å; L43-V75 HydrophobicContact CD2-CB 4.26Å; L43-V75 HydrophobicContact CD2-CG1 3.95Å; L43-V75 HydrophobicContact CG-CG1 3.67Å; L43-L79 HydrophobicContact CD1-CD2 3.81Å
44	A	81.8	Confident	78.1	Confident	44 Å²	44	56.5 Å²	56.5	36%	0.364	30%	0.296	S	S	.	.	H	α-helix	trans	-61.3	-41.5	178.3	0	0	0	0	0	111.4	L40 I41 R48	L40-A44 VanDerWaalsContact O-CB 3.3Å; L40-A44 WeakPolarHBondContact O-CB 3.47Å; L40-A44 PolarHBondContact O-N 3.04Å; I41-A44 PolarHBondContact O-N 3.21Å; A44-R48 WeakPolarHBondContact O-CB 3.27Å; A44-R48 VanDerWaalsContact O-CG 3.24Å; A44-R48 WeakPolarHBondContact O-CG 3.48Å; A44-R48 PolarHBondContact O-N 2.92Å
45	L	78.1	Confident	76.6	Confident	41 Å²	41	58.1 Å²	58.1	22%	0.215	32%	0.315	C	S	.	.	H	α-helix	trans	-64.8	-42.4	176.4	-78.5	-178	0	0	0	111.9	I41 A42 L43 R49 A316 R319	I41-L45 HydrophobicContact CG2-CD1 3.8Å; I41-L45 HydrophobicContact CG2-CG 4.19Å; I41-L45 VanDerWaalsContact O-CB 3.23Å; I41-L45 WeakPolarHBondContact O-CB 3.36Å; I41-L45 WeakPolarHBondContact O-CG 3.42Å; I41-L45 PolarHBondContact O-N 3.37Å; A42-L45 PolarHBondContact O-N 3.33Å; L43-L45 VanDerWaalsContact C-N 3.29Å; L43-L45 PolarHBondContact O-N 3.24Å; L45-R49 PolarHBondContact O-N 3.18Å; L45-A316 HydrophobicContact CD1-CB 4.14Å; L45-R319 PolarHBondContact O-NH2 3.35Å
46	L	75.8	Confident	74.9	Confident	3 Å²	3	63.2 Å²	63.2	2%	0.016	35%	0.35	C	S	.	.	H	α-helix	trans	-62.7	-54.7	173	-75	165.7	0	0	0	110.1	A42 L43 R48 R49 W50 V71 F315	A42-L46 WeakPolarHBondContact O-CB 3.36Å; A42-L46 WeakPolarHBondContact O-CG 3.49Å; A42-L46 PolarHBondContact O-N 3.3Å; L43-L46 PolarHBondContact O-N 3.04Å; L46-R48 VanDerWaalsContact C-N 3.28Å; L46-R48 PolarHBondContact O-N 2.9Å; L46-R49 WeakPolarHBondContact O-CA 3.34Å; L46-R49 WeakPolarHBondContact O-CB 3.41Å; L46-R49 PolarHBondContact O-N 3.39Å; L46-W50 PolarHBondContact O-N 3.43Å; L46-V71 HydrophobicContact CD1-CG1 4.31Å; L46-F315 HydrophobicContact CD1-CE1 4.14Å; L46-F315 HydrophobicContact CD2-CE1 3.7Å; L46-F315 HydrophobicContact CD2-CZ 3.58Å; L46-F315 HydrophobicContact CG-CE1 3.75Å; L46-F315 HydrophobicContact CG-CZ 4.17Å
47	A	78.6	Confident	72.8	Confident	39 Å²	39	63.8 Å²	63.8	32%	0.322	36%	0.356	S	S	.	.	H	α-helix	trans	-56.7	-37.7	-178.5	0	0	0	0	0	113.4	L43 W50 R51	L43-A47 VanDerWaalsContact O-CB 3.31Å; L43-A47 WeakPolarHBondContact O-CB 3.32Å; L43-A47 PolarHBondContact O-N 2.88Å; A47-W50 PolarHBondContact O-N 3.49Å; A47-R51 PolarHBondContact O-N 3.3Å
48	R	77.9	Confident	70.6	Confident	174 Å²	174	64.2 Å²	64.2	66%	0.657	37%	0.373	S	S	*	.	H	α-helix	trans	-62.6	-41	173.2	-75.5	175.4	-173.5	-165.3	3.1	112.2	A44 L46 R51 G52	A44-R48 WeakPolarHBondContact O-CB 3.27Å; A44-R48 VanDerWaalsContact O-CG 3.24Å; A44-R48 WeakPolarHBondContact O-CG 3.48Å; A44-R48 PolarHBondContact O-N 2.92Å; L46-R48 VanDerWaalsContact C-N 3.28Å; L46-R48 PolarHBondContact O-N 2.9Å; R48-R51 PolarHBondContact O-N 2.93Å; R48-G52 PolarHBondContact O-N 3.42Å
49	R	70.5	Confident	68.5	Low	87 Å²	87	68 Å²	68	33%	0.328	41%	0.412	S	S	.	.	H	α-helix	trans	-66	-45.4	176.1	-171.6	178.8	-176.7	178.1	2.7	111.1	L45 L46 R51 G52 D53 H68	L45-R49 PolarHBondContact O-N 3.18Å; L46-R49 WeakPolarHBondContact O-CA 3.34Å; L46-R49 WeakPolarHBondContact O-CB 3.41Å; L46-R49 PolarHBondContact O-N 3.39Å; R49-R51 VanDerWaalsContact C-N 3.33Å; R49-R51 PolarHBondContact O-N 3.24Å; R49-G52 PolarHBondContact O-N 2.85Å; R49-D53 WeakPolarHBondContact O-CB 3.12Å; R49-D53 PolarHBondContact O-N 3.41Å; R49-H68 PolarHBondContact NH1-NE2 3.41Å
50	W	67.9	Low	66	Low	94 Å²	94	78.2 Å²	78.2	36%	0.356	45%	0.45	S	S	.	.	H	α-helix	trans	-57	-44	175.3	-82	78.1	0	0	0	112.2	L46 A47 A54 L64	L46-W50 PolarHBondContact O-N 3.43Å; A47-W50 PolarHBondContact O-N 3.49Å; W50-A54 WeakPolarHBondContact O-CB 3.26Å; W50-A54 PolarHBondContact O-N 3.28Å; W50-L64 HydrophobicContact CD2-CD2 3.92Å; W50-L64 HydrophobicContact CE3-CD1 4.09Å; W50-L64 HydrophobicContact CE3-CD2 3.66Å; W50-L64 HydrophobicContact CH2-CD1 3.63Å; W50-L64 HydrophobicContact CH2-CD2 3.43Å; W50-L64 VanDerWaalsContact CH2-CD2 3.43Å; W50-L64 HydrophobicContact CH2-CG 4.05Å; W50-L64 HydrophobicContact CZ2-CD2 3.67Å; W50-L64 HydrophobicContact CZ3-CD1 3.27Å; W50-L64 HydrophobicContact CZ3-CD2 3.42Å; W50-L64 VanDerWaalsContact CZ3-CD2 3.42Å; W50-L64 HydrophobicContact CZ3-CG 3.96Å
51	R	70.6	Confident	63.5	Low	175 Å²	175	85.9 Å²	85.9	66%	0.66	47%	0.473	S	S	*	.	H	α-helix	trans	-67.6	-40.1	176.1	-77.7	-171.9	-75.1	-135.4	-1.6	113.3	A47 R48 R49 A54 G55	A47-R51 PolarHBondContact O-N 3.3Å; R48-R51 PolarHBondContact O-N 2.93Å; R49-R51 VanDerWaalsContact C-N 3.33Å; R49-R51 PolarHBondContact O-N 3.24Å; R51-A54 PolarHBondContact O-N 3.49Å; R51-G55 PolarHBondContact O-N 3.12Å; R51-G55 VanDerWaalsContact O-N 3.12Å
52	G	65.1	Low	61.3	Low	41 Å²	41	86.3 Å²	86.3	42%	0.423	48%	0.482	S	S	.	.	H	α-helix	trans	-63.1	-42.2	175.2	0	0	0	0	0	112.5	R48 R49 G55 C56	R48-G52 PolarHBondContact O-N 3.42Å; R49-G52 PolarHBondContact O-N 2.85Å; G52-G55 PolarHBondContact O-N 3.24Å; G52-C56 PolarHBondContact O-N 2.95Å
53	D	60.8	Low	59.5	Low	71 Å²	71	90.3 Å²	90.3	38%	0.38	51%	0.51	S	S	.	.	H	α-helix	trans	-68.9	-36.9	177.2	-71.3	-21.7	0	0	0	111.5	R49 G55 C56 S57	R49-D53 WeakPolarHBondContact O-CB 3.12Å; R49-D53 PolarHBondContact O-N 3.41Å; D53-G55 PolarHBondContact O-N 3.04Å; D53-C56 PolarHBondContact O-N 2.91Å; D53-S57 WeakPolarHBondContact O-CB 3.25Å; D53-S57 PolarHBondContact O-N 3.42Å; D53-S57 PolarHBondContact O-OG 3.28Å
54	A	58.4	Low	58.2	Low	68 Å²	68	92.1 Å²	92.1	56%	0.562	52%	0.519	S	S	*	.	H	α-helix	trans	-63.4	-37.9	174.9	0	0	0	0	0	112.8	W50 R51 S57	W50-A54 WeakPolarHBondContact O-CB 3.26Å; W50-A54 PolarHBondContact O-N 3.28Å; R51-A54 PolarHBondContact O-N 3.49Å; A54-S57 PolarHBondContact O-N 3.42Å
55	G	54.3	Low	57.7	Low	63 Å²	63	91.7 Å²	91.7	65%	0.649	51%	0.513	S	S	*	.	H	α-helix	trans	-67.4	-33.3	176.6	0	0	0	0	0	114.1	R51 G52 D53	R51-G55 PolarHBondContact O-N 3.12Å; R51-G55 VanDerWaalsContact O-N 3.12Å; G52-G55 PolarHBondContact O-N 3.24Å; D53-G55 PolarHBondContact O-N 3.04Å
56	C	48.7	Very low	57.6	Low	107 Å²	107	90.8 Å²	90.8	72%	0.723	51%	0.509	S	S	*	.	H	α-helix	trans	-88.6	-15.2	176.8	-70.4	0	0	0	0	113.8	G52 D53 A58	G52-C56 PolarHBondContact O-N 2.95Å; D53-C56 PolarHBondContact O-N 2.91Å; C56-A58 VanDerWaalsContact C-N 3.34Å; C56-A58 PolarHBondContact O-N 3.3Å
57	S	44	Very low	57.5	Low	43 Å²	43	90.8 Å²	90.8	30%	0.301	51%	0.508	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.7	2.8	-173.7	-67.9	0	0	0	0	115.1	D53 A54 G59	D53-S57 WeakPolarHBondContact O-CB 3.25Å; D53-S57 PolarHBondContact O-N 3.42Å; D53-S57 PolarHBondContact O-OG 3.28Å; A54-S57 PolarHBondContact O-N 3.42Å; S57-G59 PolarHBondContact O-N 2.93Å
58	A	43.7	Very low	57.4	Low	105 Å²	105	90.2 Å²	90.2	87%	0.868	50%	0.499	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.9	-15.7	171.1	0	0	0	0	0	113.1	C56	C56-A58 VanDerWaalsContact C-N 3.34Å; C56-A58 PolarHBondContact O-N 3.3Å
59	G	38.3	Very low	57.7	Low	79 Å²	79	83.7 Å²	83.7	81%	0.814	48%	0.478	S	S	*	.	S	Bend	trans	-127.4	-8.5	176.2	0	0	0	0	0	116.9	S57	S57-G59 PolarHBondContact O-N 2.93Å
60	R	34.7	Very low	58.3	Low	215 Å²	215	80 Å²	80	81%	0.811	47%	0.465	S	S	*	.			trans	-145.1	107	-177	-163.3	156.9	170.6	164.5	-6	110.8	S62	R60-S62 PolarHBondContact O-N 3.07Å
61	R	33.8	Very low	59	Low	251 Å²	251	75.6 Å²	75.6	95%	0.947	45%	0.449	S	S	*	.			trans	-62.4	76.6	178.9	-137	172.9	-168.4	141.7	-1.1	110.2	S63	R61-S63 PolarHBondContact O-N 3Å
62	S	38.9	Very low	59.6	Low	71 Å²	71	69 Å²	69	50%	0.497	43%	0.428	S	S	.	.			trans	-71.1	112.5	168.1	64.9	0	0	0	0	106.8	R60 L64	R60-S62 PolarHBondContact O-N 3.07Å; S62-L64 PolarHBondContact O-N 3.44Å
63	S	44.9	Very low	60.7	Low	84 Å²	84	69.3 Å²	69.3	59%	0.587	42%	0.418	S	S	*	.			trans	-68	106.7	177.9	53	0	0	0	0	108.7	R61 S65 R150	R61-S63 PolarHBondContact O-N 3Å; S63-S65 PolarHBondContact O-N 3.32Å; S63-R150 VanDerWaalsContact CB-NH2 3.3Å
64	L	55.6	Low	62	Low	80 Å²	80	66 Å²	66	42%	0.419	40%	0.401	S	S	.	.			trans	-37.8	110.9	160.1	-74.6	160.6	0	0	0	109.5	W50 S62 R150	W50-L64 HydrophobicContact CD2-CD2 3.92Å; W50-L64 HydrophobicContact CE3-CD1 4.09Å; W50-L64 HydrophobicContact CE3-CD2 3.66Å; W50-L64 HydrophobicContact CH2-CD1 3.63Å; W50-L64 HydrophobicContact CH2-CD2 3.43Å; W50-L64 VanDerWaalsContact CH2-CD2 3.43Å; W50-L64 HydrophobicContact CH2-CG 4.05Å; W50-L64 HydrophobicContact CZ2-CD2 3.67Å; W50-L64 HydrophobicContact CZ3-CD1 3.27Å; W50-L64 HydrophobicContact CZ3-CD2 3.42Å; W50-L64 VanDerWaalsContact CZ3-CD2 3.42Å; W50-L64 HydrophobicContact CZ3-CG 3.96Å; S62-L64 PolarHBondContact O-N 3.44Å; L64-R150 PolarHBondContact O-NH2 3.31Å
65	S	70.2	Confident	63.4	Low	35 Å²	35	62.9 Å²	62.9	25%	0.245	38%	0.375	C	S	.	.			trans	-77.4	139	-176.7	147.2	0	0	0	0	109.1	S63 F67 H68	S63-S65 PolarHBondContact O-N 3.32Å; S65-F67 PolarHBondContact O-N 2.86Å; S65-F67 VanDerWaalsContact O-N 3.15Å; S65-F67 WeakPolarHBondContact OG-CB 3.21Å; S65-H68 PolarHBondContact O-N 2.93Å
66	L	76.1	Confident	65.1	Low	22 Å²	22	64.2 Å²	64.2	12%	0.115	36%	0.362	C	S	.	.	H	α-helix	trans	-50.8	-38.2	-179	-73.6	170.3	0	0	0	112.3	H68 V69 L70 E133 V148	L66-H68 VanDerWaalsContact C-N 3.32Å; L66-H68 PolarHBondContact O-N 3.15Å; L66-V69 WeakPolarHBondContact O-CB 3.34Å; L66-V69 PolarHBondContact O-N 3.47Å; L66-V69 VanDerWaalsContact O-N 3.07Å; L66-L70 WeakPolarHBondContact O-CG 3.42Å; L66-L70 PolarHBondContact O-N 3.25Å; L66-E133 HydrophobicContact CB-CG 4.26Å; L66-V148 HydrophobicContact CD1-CG1 3.6Å
67	F	75.5	Confident	67.1	Low	2 Å²	2	59.2 Å²	59.2	1%	0.009	33%	0.329	C	S	.	.	H	α-helix	trans	-48.5	-45.3	170	-178.6	-103.6	0	0	0	115.5	S65 V69 L70 V71 E133 R134 H262 L266	S65-F67 PolarHBondContact O-N 2.86Å; S65-F67 VanDerWaalsContact O-N 3.15Å; S65-F67 WeakPolarHBondContact OG-CB 3.21Å; F67-V69 VanDerWaalsContact C-N 3.26Å; F67-V69 PolarHBondContact O-N 2.99Å; F67-L70 PolarHBondContact O-N 3.42Å; F67-V71 HydrophobicContact CD1-CG2 4.18Å; F67-V71 HydrophobicContact CD2-CG2 4.3Å; F67-V71 HydrophobicContact CE1-CG2 3.83Å; F67-V71 HydrophobicContact CE2-CG2 3.93Å; F67-V71 HydrophobicContact CG-CG2 4.41Å; F67-V71 HydrophobicContact CZ-CG2 3.7Å; F67-V71 WeakPolarHBondContact O-CB 3.34Å; F67-V71 VanDerWaalsContact O-CG2 3.26Å; F67-V71 WeakPolarHBondContact O-CG2 3.42Å; F67-V71 PolarHBondContact O-N 2.93Å; F67-E133 WeakPolarHBondContact CB-OE2 3.36Å; F67-E133 PolarHBondContact N-OE1 3.41Å; F67-R134 VanDerWaalsContact CD1-NH2 3.3Å; F67-R134 HydrophobicContact CD2-CG 4.35Å; F67-H262 AromaticContact CD1-CE1 3.92Å; F67-H262 AromaticContact CD1-ND1 3.39Å; F67-H262 WeakPolarHBondContact CD1-ND1 3.19Å; F67-H262 AromaticContact CE1-CE1 3.79Å; F67-H262 AromaticContact CE1-ND1 3.16Å; F67-H262 WeakPolarHBondContact CE1-ND1 3.45Å; F67-L266 HydrophobicContact CE2-CD1 4Å; F67-L266 HydrophobicContact CE2-CD2 3.71Å; F67-L266 HydrophobicContact CE2-CG 3.88Å; F67-L266 HydrophobicContact CZ-CG 4.34Å
68	H	75.7	Confident	69.3	Low	28 Å²	28	57.2 Å²	57.2	13%	0.13	32%	0.315	C	S	.	.	H	α-helix	trans	-68.6	-32.5	-178.3	-69.7	82.8	0	0	0	111.3	R49 S65 L66 T72 H262	R49-H68 PolarHBondContact NH1-NE2 3.41Å; S65-H68 PolarHBondContact O-N 2.93Å; L66-H68 VanDerWaalsContact C-N 3.32Å; L66-H68 PolarHBondContact O-N 3.15Å; H68-T72 WeakPolarHBondContact O-CB 3.3Å; H68-T72 PolarHBondContact O-N 2.97Å; H68-T72 PolarHBondContact O-OG1 3.42Å; H68-H262 AromaticContact CE1-CE1 3.42Å; H68-H262 PolarHBondContact CE1-CE1 3.31Å; H68-H262 VanDerWaalsContact CE1-CE1 3.42Å; H68-H262 AromaticContact NE2-CE1 3.52Å
69	V	83.2	Confident	71.5	Confident	36 Å²	36	53.4 Å²	53.4	22%	0.218	28%	0.279	C	S	.	.	H	α-helix	trans	-67.4	-50	173.7	178.6	0	0	0	0	109.6	L66 F67 V71 T72 E73 L154 L157	L66-V69 WeakPolarHBondContact O-CB 3.34Å; L66-V69 PolarHBondContact O-N 3.47Å; L66-V69 VanDerWaalsContact O-N 3.07Å; F67-V69 VanDerWaalsContact C-N 3.26Å; F67-V69 PolarHBondContact O-N 2.99Å; V69-V71 VanDerWaalsContact C-N 3.35Å; V69-V71 PolarHBondContact O-N 2.78Å; V69-T72 PolarHBondContact O-N 2.87Å; V69-T72 VanDerWaalsContact O-N 3.15Å; V69-E73 WeakPolarHBondContact O-CB 3.16Å; V69-E73 PolarHBondContact O-N 3.28Å; V69-L154 HydrophobicContact CG1-CD1 3.93Å; V69-L157 HydrophobicContact CG1-CD1 4.02Å
70	L	84.2	Confident	74	Confident	10 Å²	10	52.9 Å²	52.9	5%	0.052	26%	0.258	C	S	.	.	H	α-helix	trans	-58.5	-42.9	177.8	-67.7	169.4	0	0	0	112.5	L66 F67 E73 L74 M126 A129 M130 E133 L157	L66-L70 WeakPolarHBondContact O-CG 3.42Å; L66-L70 PolarHBondContact O-N 3.25Å; F67-L70 PolarHBondContact O-N 3.42Å; L70-E73 PolarHBondContact O-N 3.46Å; L70-L74 WeakPolarHBondContact O-CB 3.21Å; L70-L74 PolarHBondContact O-N 3.25Å; L70-M126 HydrophobicContact CB-SD 4.37Å; L70-M126 HydrophobicContact CD2-SD 3.58Å; L70-M126 VanDerWaalsContact CD2-SD 3.58Å; L70-A129 HydrophobicContact CD1-CB 4.46Å; L70-A129 HydrophobicContact CD2-CB 4.31Å; L70-M130 HydrophobicContact CB-CG 3.51Å; L70-M130 HydrophobicContact CB-SD 4.08Å; L70-M130 HydrophobicContact CD1-CG 3.84Å; L70-M130 HydrophobicContact CG-CG 4.26Å; L70-E133 HydrophobicContact CD1-CB 4.42Å; L70-L157 HydrophobicContact CD2-CD2 3.69Å
71	V	82	Confident	76.7	Confident	2 Å²	2	42.9 Å²	42.9	1%	0.012	22%	0.221	C	C	.	.	H	α-helix	trans	-66.7	-40.3	176.4	170.5	0	0	0	0	111.6	L46 F67 V69 E73 L74 V75 M130 F315	L46-V71 HydrophobicContact CD1-CG1 4.31Å; F67-V71 HydrophobicContact CD1-CG2 4.18Å; F67-V71 HydrophobicContact CD2-CG2 4.3Å; F67-V71 HydrophobicContact CE1-CG2 3.83Å; F67-V71 HydrophobicContact CE2-CG2 3.93Å; F67-V71 HydrophobicContact CG-CG2 4.41Å; F67-V71 HydrophobicContact CZ-CG2 3.7Å; F67-V71 WeakPolarHBondContact O-CB 3.34Å; F67-V71 VanDerWaalsContact O-CG2 3.26Å; F67-V71 WeakPolarHBondContact O-CG2 3.42Å; F67-V71 PolarHBondContact O-N 2.93Å; V69-V71 VanDerWaalsContact C-N 3.35Å; V69-V71 PolarHBondContact O-N 2.78Å; V71-E73 VanDerWaalsContact C-N 3.31Å; V71-L74 WeakPolarHBondContact O-CB 3.49Å; V71-L74 PolarHBondContact O-N 2.97Å; V71-V75 WeakPolarHBondContact O-CG2 3.35Å; V71-V75 PolarHBondContact O-N 2.93Å; V71-V75 VanDerWaalsContact O-N 3.1Å; V71-M130 HydrophobicContact CB-SD 4.43Å; V71-M130 HydrophobicContact CG2-SD 3.53Å; V71-M130 VanDerWaalsContact CG2-SD 3.53Å; V71-F315 HydrophobicContact CG1-CD2 3.7Å; V71-F315 HydrophobicContact CG1-CE1 4.39Å; V71-F315 HydrophobicContact CG1-CE2 3.49Å; V71-F315 VanDerWaalsContact CG1-CE2 3.49Å; V71-F315 HydrophobicContact CG1-CG 4.29Å; V71-F315 HydrophobicContact CG1-CZ 3.87Å
72	T	83.1	Confident	79.3	Confident	36 Å²	36	31.5 Å²	31.5	22%	0.221	18%	0.18	C	C	.	.	H	α-helix	trans	-64.3	-42.7	177.6	-55.6	0	0	0	0	110.2	L43 H68 V69 V75 F76	L43-T72 HydrophobicContact CD2-CG2 4.31Å; H68-T72 WeakPolarHBondContact O-CB 3.3Å; H68-T72 PolarHBondContact O-N 2.97Å; H68-T72 PolarHBondContact O-OG1 3.42Å; V69-T72 PolarHBondContact O-N 2.87Å; V69-T72 VanDerWaalsContact O-N 3.15Å; T72-V75 PolarHBondContact O-N 3.36Å; T72-F76 WeakPolarHBondContact O-CB 3.31Å; T72-F76 PolarHBondContact O-N 2.92Å
73	E	88.8	Confident	81.8	Confident	47 Å²	47	30.9 Å²	30.9	22%	0.22	18%	0.175	C	C	.	.	H	α-helix	trans	-67.1	-37.2	177.6	-162.4	66.5	-169.7	0	0	112.2	V69 L70 V71 F76 T77 M126 L157 Y161	V69-E73 WeakPolarHBondContact O-CB 3.16Å; V69-E73 PolarHBondContact O-N 3.28Å; L70-E73 PolarHBondContact O-N 3.46Å; V71-E73 VanDerWaalsContact C-N 3.31Å; E73-F76 PolarHBondContact O-N 2.92Å; E73-T77 VanDerWaalsContact O-CB 3.32Å; E73-T77 WeakPolarHBondContact O-CB 3.17Å; E73-T77 PolarHBondContact O-N 3.22Å; E73-T77 PolarHBondContact O-OG1 2.86Å; E73-M126 HydrophobicContact CB-CE 3.85Å; E73-M126 HydrophobicContact CB-SD 4.46Å; E73-M126 HydrophobicContact CG-CE 3.55Å; E73-L157 HydrophobicContact CB-CD1 4.36Å; E73-L157 HydrophobicContact CB-CD2 4.05Å; E73-L157 HydrophobicContact CG-CD1 4.12Å; E73-L157 HydrophobicContact CG-CD2 3.9Å; E73-Y161 HydrophobicContact CG-CE2 4.31Å; E73-Y161 VanDerWaalsContact CG-OH 3.29Å; E73-Y161 WeakPolarHBondContact CG-OH 3.18Å; E73-Y161 PolarHBondContact OE1-OH 3.48Å
74	L	87.8	Confident	84	Confident	3 Å²	3	30.2 Å²	30.2	2%	0.016	17%	0.165	C	C	.	.	H	α-helix	trans	-56.6	-54.9	172.5	-176.4	82	0	0	0	111.1	L70 V71 F76 T77 D78 T123 M126 L127 M130 M269	L70-L74 WeakPolarHBondContact O-CB 3.21Å; L70-L74 PolarHBondContact O-N 3.25Å; V71-L74 WeakPolarHBondContact O-CB 3.49Å; V71-L74 PolarHBondContact O-N 2.97Å; L74-F76 VanDerWaalsContact C-N 3.26Å; L74-F76 PolarHBondContact O-N 3.3Å; L74-T77 WeakPolarHBondContact O-CB 3.45Å; L74-T77 PolarHBondContact O-N 3.44Å; L74-T77 VanDerWaalsContact O-N 3.1Å; L74-D78 PolarHBondContact O-N 2.85Å; L74-T123 HydrophobicContact CD1-CG2 3.75Å; L74-M126 HydrophobicContact CB-CG 4.1Å; L74-M126 HydrophobicContact CD1-CB 3.88Å; L74-M126 HydrophobicContact CD1-CG 3.95Å; L74-L127 HydrophobicContact CD1-CG 4.29Å; L74-L127 HydrophobicContact CD2-CD2 4.46Å; L74-M130 HydrophobicContact CD1-CE 4.21Å; L74-M130 HydrophobicContact CD2-CE 3.83Å; L74-M130 HydrophobicContact CG-CE 4.45Å; L74-M269 HydrophobicContact CD2-CE 3.58Å
75	V	88.1	Confident	85.7	Confident	2 Å²	2	27.6 Å²	27.6	1%	0.012	15%	0.151	C	C	.	.	H	α-helix	trans	-63.1	-36.3	-179.3	179.7	0	0	0	0	111	N39 A42 L43 V71 T72 L79	N39-V75 HydrophobicContact CB-CG1 4.08Å; N39-V75 WeakPolarHBondContact O-CG1 3.08Å; N39-V75 VanDerWaalsContact OD1-CG1 3.32Å; N39-V75 WeakPolarHBondContact OD1-CG1 3.22Å; N39-V75 PolarHBondContact OD1-O 3.42Å; N39-V75 VanDerWaalsContact OD1-O 3.07Å; A42-V75 HydrophobicContact CB-CG1 3.81Å; A42-V75 HydrophobicContact CB-CG2 4.1Å; L43-V75 HydrophobicContact CD1-CG1 4.45Å; L43-V75 HydrophobicContact CD2-CB 4.26Å; L43-V75 HydrophobicContact CD2-CG1 3.95Å; L43-V75 HydrophobicContact CG-CG1 3.67Å; V71-V75 WeakPolarHBondContact O-CG2 3.35Å; V71-V75 PolarHBondContact O-N 2.93Å; V71-V75 VanDerWaalsContact O-N 3.1Å; T72-V75 PolarHBondContact O-N 3.36Å; V75-L79 VanDerWaalsContact O-CB 3.3Å; V75-L79 WeakPolarHBondContact O-CB 3.25Å; V75-L79 PolarHBondContact O-N 3.43Å
76	F	89.8	Confident	86.6	Confident	90 Å²	90	27 Å²	27	40%	0.395	15%	0.147	S	C	.	.	H	α-helix	trans	-65.4	-43.3	174	-176.2	-107.6	0	0	0	112	T72 E73 L74 L79 L80	T72-F76 WeakPolarHBondContact O-CB 3.31Å; T72-F76 PolarHBondContact O-N 2.92Å; E73-F76 PolarHBondContact O-N 2.92Å; L74-F76 VanDerWaalsContact C-N 3.26Å; L74-F76 PolarHBondContact O-N 3.3Å; F76-L79 PolarHBondContact O-N 2.99Å; F76-L80 HydrophobicContact CD1-CD1 3.83Å; F76-L80 HydrophobicContact CD1-CG 4.4Å; F76-L80 HydrophobicContact CE1-CD1 3.32Å; F76-L80 HydrophobicContact CE1-CG 4.06Å; F76-L80 HydrophobicContact CE2-CG 4.45Å; F76-L80 HydrophobicContact CZ-CD1 3.72Å; F76-L80 HydrophobicContact CZ-CD2 4.32Å; F76-L80 HydrophobicContact CZ-CG 4.07Å; F76-L80 WeakPolarHBondContact O-CB 3.48Å; F76-L80 WeakPolarHBondContact O-CG 3.31Å; F76-L80 PolarHBondContact O-N 2.96Å
77	T	91.1	Very high	87.2	Confident	2 Å²	2	28.6 Å²	28.6	1%	0.012	16%	0.158	C	C	.	.	H	α-helix	trans	-63.1	-45.3	177	-56	0	0	0	0	111.6	E73 L74 L80 G81 F119 A122 Y161	E73-T77 VanDerWaalsContact O-CB 3.32Å; E73-T77 WeakPolarHBondContact O-CB 3.17Å; E73-T77 PolarHBondContact O-N 3.22Å; E73-T77 PolarHBondContact O-OG1 2.86Å; L74-T77 WeakPolarHBondContact O-CB 3.45Å; L74-T77 PolarHBondContact O-N 3.44Å; L74-T77 VanDerWaalsContact O-N 3.1Å; T77-L80 PolarHBondContact O-N 2.81Å; T77-G81 PolarHBondContact O-N 3.28Å; T77-F119 HydrophobicContact CG2-CD1 3.82Å; T77-F119 HydrophobicContact CG2-CE1 4.31Å; T77-A122 HydrophobicContact CG2-CB 4.29Å; T77-Y161 HydrophobicContact CG2-CE1 4.21Å; T77-Y161 PolarHBondContact OG1-OH 3.14Å
78	D	89.8	Confident	87.9	Confident	1 Å²	1	29.8 Å²	29.8	1%	0.005	17%	0.165	C	C	.	.	H	α-helix	trans	-66.5	-38	178.8	-72.2	-28.1	0	0	0	111.7	L74 G81 T82 T123 S308	L74-D78 PolarHBondContact O-N 2.85Å; D78-G81 PolarHBondContact O-N 3.49Å; D78-T82 WeakPolarHBondContact O-CB 3.26Å; D78-T82 PolarHBondContact O-N 2.61Å; D78-T82 PolarHBondContact O-OG1 2.9Å; D78-T123 PolarHBondContact OD1-OG1 2.87Å; D78-S308 VanDerWaalsContact OD1-CB 3.23Å; D78-S308 WeakPolarHBondContact OD1-CB 3.29Å; D78-S308 PolarHBondContact OD1-OG 2.97Å
79	L	89.8	Confident	88.5	Confident	25 Å²	25	28.7 Å²	28.7	13%	0.131	16%	0.161	C	C	.	.	H	α-helix	trans	-63.6	-47.7	172.9	-177.2	61.3	0	0	0	111.4	V36 N39 L40 L43 V75 F76 G81 T82 C83	V36-L79 HydrophobicContact CG1-CD1 4.47Å; V36-L79 HydrophobicContact CG2-CD1 4.49Å; N39-L79 HydrophobicContact CB-CB 3.9Å; N39-L79 HydrophobicContact CB-CD1 3.9Å; N39-L79 HydrophobicContact CB-CG 4.37Å; L40-L79 HydrophobicContact CD2-CD2 4.09Å; L43-L79 HydrophobicContact CD1-CD2 3.81Å; V75-L79 VanDerWaalsContact O-CB 3.3Å; V75-L79 WeakPolarHBondContact O-CB 3.25Å; V75-L79 PolarHBondContact O-N 3.43Å; F76-L79 PolarHBondContact O-N 2.99Å; L79-G81 VanDerWaalsContact C-N 3.34Å; L79-G81 PolarHBondContact O-N 3.02Å; L79-T82 PolarHBondContact O-N 3.5Å; L79-C83 WeakPolarHBondContact O-CB 3.44Å; L79-C83 PolarHBondContact O-N 3.04Å; L79-C83 PolarHBondContact O-SG 2.73Å
80	L	92.1	Very high	88.8	Confident	68 Å²	68	29.3 Å²	29.3	36%	0.356	16%	0.163	S	C	.	.	H	α-helix	trans	-58.5	-47.2	176	-77.9	179.6	0	0	0	110.9	F76 T77 T82 C83 L84 F119	F76-L80 HydrophobicContact CD1-CD1 3.83Å; F76-L80 HydrophobicContact CD1-CG 4.4Å; F76-L80 HydrophobicContact CE1-CD1 3.32Å; F76-L80 HydrophobicContact CE1-CG 4.06Å; F76-L80 HydrophobicContact CE2-CG 4.45Å; F76-L80 HydrophobicContact CZ-CD1 3.72Å; F76-L80 HydrophobicContact CZ-CD2 4.32Å; F76-L80 HydrophobicContact CZ-CG 4.07Å; F76-L80 WeakPolarHBondContact O-CB 3.48Å; F76-L80 WeakPolarHBondContact O-CG 3.31Å; F76-L80 PolarHBondContact O-N 2.96Å; T77-L80 PolarHBondContact O-N 2.81Å; L80-T82 PolarHBondContact O-N 3.44Å; L80-C83 PolarHBondContact O-N 2.89Å; L80-L84 HydrophobicContact CB-CD1 4.48Å; L80-L84 WeakPolarHBondContact O-CB 3.5Å; L80-L84 WeakPolarHBondContact O-CG 3.14Å; L80-L84 PolarHBondContact O-N 3.32Å; L80-F119 HydrophobicContact CB-CE1 3.99Å; L80-F119 HydrophobicContact CB-CZ 4.28Å
81	G	89.9	Confident	89	Confident	5 Å²	5	30.6 Å²	30.6	5%	0.052	18%	0.175	C	C	.	.	H	α-helix	trans	-58.2	-47.3	176.7	0	0	0	0	0	112.3	T77 D78 L79 C83 L84 I85	T77-G81 PolarHBondContact O-N 3.28Å; D78-G81 PolarHBondContact O-N 3.49Å; L79-G81 VanDerWaalsContact C-N 3.34Å; L79-G81 PolarHBondContact O-N 3.02Å; G81-C83 PolarHBondContact O-N 2.78Å; G81-L84 PolarHBondContact O-N 3.29Å; G81-I85 WeakPolarHBondContact O-CB 3.19Å; G81-I85 WeakPolarHBondContact O-CG1 3.49Å; G81-I85 PolarHBondContact O-N 3.43Å
82	T	89.4	Confident	89.3	Confident	12 Å²	12	30.5 Å²	30.5	7%	0.074	17%	0.174	C	C	.	.	H	α-helix	trans	-60.4	-45.9	177.1	-57	0	0	0	0	111.4	F32 V36 D78 L79 L80 L84 S86	F32-T82 HydrophobicContact CD2-CG2 3.79Å; F32-T82 HydrophobicContact CE2-CG2 4.26Å; V36-T82 HydrophobicContact CG2-CG2 3.9Å; D78-T82 WeakPolarHBondContact O-CB 3.26Å; D78-T82 PolarHBondContact O-N 2.61Å; D78-T82 PolarHBondContact O-OG1 2.9Å; L79-T82 PolarHBondContact O-N 3.5Å; L80-T82 PolarHBondContact O-N 3.44Å; T82-L84 VanDerWaalsContact C-N 3.33Å; T82-L84 PolarHBondContact O-N 3.5Å; T82-S86 WeakPolarHBondContact O-CB 3.3Å; T82-S86 PolarHBondContact O-N 2.95Å; T82-S86 PolarHBondContact O-OG 3.23Å
83	C	90.9	Very high	89.5	Confident	58 Å²	58	29.6 Å²	29.6	39%	0.392	17%	0.167	S	C	.	.	H	α-helix	trans	-70.4	-25.7	179.6	-70.7	0	0	0	0	113.7	L79 L80 G81 P87	L79-C83 WeakPolarHBondContact O-CB 3.44Å; L79-C83 PolarHBondContact O-N 3.04Å; L79-C83 PolarHBondContact O-SG 2.73Å; L80-C83 PolarHBondContact O-N 2.89Å; G81-C83 PolarHBondContact O-N 2.78Å; C83-P87 WeakPolarHBondContact O-CD 3.31Å; C83-P87 WeakPolarHBondContact O-CG 3.18Å
84	L	91.3	Very high	89.5	Confident	71 Å²	71	31.4 Å²	31.4	37%	0.372	19%	0.189	S	C	.	.	H	α-helix	trans	-92.8	-27.9	-178.1	-72.6	171.7	0	0	0	113.1	L80 G81 T82 Y111 F119	L80-L84 HydrophobicContact CB-CD1 4.48Å; L80-L84 WeakPolarHBondContact O-CB 3.5Å; L80-L84 WeakPolarHBondContact O-CG 3.14Å; L80-L84 PolarHBondContact O-N 3.32Å; G81-L84 PolarHBondContact O-N 3.29Å; T82-L84 VanDerWaalsContact C-N 3.33Å; T82-L84 PolarHBondContact O-N 3.5Å; L84-Y111 WeakPolarHBondContact CB-OH 3.24Å; L84-Y111 WeakPolarHBondContact O-CE1 3.29Å; L84-Y111 PolarHBondContact O-OH 3.42Å; L84-Y111 VanDerWaalsContact O-OH 3.04Å; L84-F119 HydrophobicContact CB-CE2 4.24Å; L84-F119 HydrophobicContact CD1-CE2 3.85Å; L84-F119 HydrophobicContact CD1-CZ 3.53Å
85	I	90.4	Very high	89.5	Confident	25 Å²	25	39 Å²	39	13%	0.128	22%	0.218	C	C	.	.	H	α-helix	trans	-95.2	-50.6	-176.8	-63.5	171.7	0	0	0	110.9	G81 V88 F112 A115 M116 F119	G81-I85 WeakPolarHBondContact O-CB 3.19Å; G81-I85 WeakPolarHBondContact O-CG1 3.49Å; G81-I85 PolarHBondContact O-N 3.43Å; I85-V88 WeakPolarHBondContact O-CB 3.26Å; I85-V88 PolarHBondContact O-N 3.45Å; I85-F112 HydrophobicContact CG2-CD2 3.8Å; I85-F112 HydrophobicContact CG2-CE2 3.25Å; I85-F112 HydrophobicContact CG2-CZ 3.93Å; I85-A115 HydrophobicContact CD1-CB 4.4Å; I85-A115 HydrophobicContact CG1-CB 3.94Å; I85-M116 HydrophobicContact CD1-CB 4.29Å; I85-F119 HydrophobicContact CD1-CD2 3.97Å; I85-F119 HydrophobicContact CG1-CD2 4.43Å
86	S	88.8	Confident	89.4	Confident	23 Å²	23	43.9 Å²	43.9	16%	0.161	24%	0.244	C	C	.	.	H	α-helix	trans	-66.4	-38.5	-169.6	-57.5	0	0	0	0	114.8	T82 V88 V89 L90	T82-S86 WeakPolarHBondContact O-CB 3.3Å; T82-S86 PolarHBondContact O-N 2.95Å; T82-S86 PolarHBondContact O-OG 3.23Å; S86-V88 PolarHBondContact O-N 2.89Å; S86-V89 WeakPolarHBondContact O-CB 3.3Å; S86-V89 PolarHBondContact O-N 2.95Å; S86-V89 VanDerWaalsContact O-N 3.16Å; S86-L90 WeakPolarHBondContact O-CG 3.49Å; S86-L90 PolarHBondContact O-N 3.49Å
87	P	90.4	Very high	89.3	Confident	55 Å²	55	41.8 Å²	41.8	36%	0.357	24%	0.235	S	C	.	.	H	α-helix	trans	-62.1	-30.3	176.9	-27.9	38.9	0	0	0	113.6	F32 C83 V89 L90 A91	F32-P87 HydrophobicContact CE2-CG 4.44Å; C83-P87 WeakPolarHBondContact O-CD 3.31Å; C83-P87 WeakPolarHBondContact O-CG 3.18Å; P87-V89 VanDerWaalsContact C-N 3.35Å; P87-L90 PolarHBondContact O-N 3.4Å; P87-A91 VanDerWaalsContact O-CB 3.31Å; P87-A91 WeakPolarHBondContact O-CB 3.45Å; P87-A91 PolarHBondContact O-N 2.82Å
88	V	90.1	Very high	89.1	Confident	26 Å²	26	41.7 Å²	41.7	16%	0.158	24%	0.235	C	C	.	.	H	α-helix	trans	-65.3	-42	176.1	-174.7	0	0	0	0	110.5	I85 S86 A91 S92 L99 L102 Y111	I85-V88 WeakPolarHBondContact O-CB 3.26Å; I85-V88 PolarHBondContact O-N 3.45Å; S86-V88 PolarHBondContact O-N 2.89Å; V88-A91 PolarHBondContact O-N 3.25Å; V88-S92 PolarHBondContact O-N 2.92Å; V88-L99 HydrophobicContact CG1-CD2 3.47Å; V88-L99 VanDerWaalsContact CG1-CD2 3.47Å; V88-L102 HydrophobicContact CG1-CD2 4.15Å; V88-Y111 HydrophobicContact CG2-CD1 4.27Å; V88-Y111 HydrophobicContact CG2-CE1 3.82Å
89	V	88.6	Confident	88.9	Confident	5 Å²	5	41.7 Å²	41.7	3%	0.03	24%	0.235	C	C	.	.	H	α-helix	trans	-63	-46.1	174.5	-179.6	0	0	0	0	110.8	S86 P87 A91 S92 Y93 F112	S86-V89 WeakPolarHBondContact O-CB 3.3Å; S86-V89 PolarHBondContact O-N 2.95Å; S86-V89 VanDerWaalsContact O-N 3.16Å; P87-V89 VanDerWaalsContact C-N 3.35Å; V89-A91 VanDerWaalsContact C-N 3.32Å; V89-A91 PolarHBondContact O-N 2.91Å; V89-S92 WeakPolarHBondContact O-CB 3.4Å; V89-S92 PolarHBondContact O-N 3.33Å; V89-Y93 HydrophobicContact CG1-CD2 3.95Å; V89-Y93 HydrophobicContact CG1-CE2 3.66Å; V89-Y93 VanDerWaalsContact O-CD2 3.23Å; V89-Y93 WeakPolarHBondContact O-CD2 3.35Å; V89-Y93 PolarHBondContact O-N 3.44Å; V89-Y93 VanDerWaalsContact O-N 3.11Å; V89-F112 HydrophobicContact CG2-CD2 4.19Å; V89-F112 HydrophobicContact CG2-CE2 3.34Å; V89-F112 HydrophobicContact CG2-CZ 3.99Å
90	L	88.3	Confident	88.7	Confident	50 Å²	50	41.9 Å²	41.9	26%	0.262	24%	0.237	S	C	.	.	H	α-helix	trans	-64.7	-36	178.5	-66.6	175.6	0	0	0	112.3	F32 S86 P87 S92 Y93 A94	F32-L90 HydrophobicContact CD1-CD1 4.16Å; F32-L90 HydrophobicContact CG-CD1 4.41Å; S86-L90 WeakPolarHBondContact O-CG 3.49Å; S86-L90 PolarHBondContact O-N 3.49Å; P87-L90 PolarHBondContact O-N 3.4Å; L90-S92 VanDerWaalsContact C-N 3.35Å; L90-Y93 PolarHBondContact O-N 3.41Å; L90-A94 WeakPolarHBondContact O-CB 3.39Å; L90-A94 PolarHBondContact O-N 3.14Å
91	A	88.9	Confident	88.4	Confident	37 Å²	37	40 Å²	40	31%	0.306	23%	0.231	S	C	.	.	H	α-helix	trans	-65.2	-38.4	174.7	0	0	0	0	0	112.1	P87 V88 V89 A94 R95 L102	P87-A91 VanDerWaalsContact O-CB 3.31Å; P87-A91 WeakPolarHBondContact O-CB 3.45Å; P87-A91 PolarHBondContact O-N 2.82Å; V88-A91 PolarHBondContact O-N 3.25Å; V89-A91 VanDerWaalsContact C-N 3.32Å; V89-A91 PolarHBondContact O-N 2.91Å; A91-A94 PolarHBondContact O-N 3.44Å; A91-R95 PolarHBondContact O-N 3.2Å; A91-L102 HydrophobicContact CB-CD2 4.29Å
92	S	88.6	Confident	88.3	Confident	0 Å²	0	41.4 Å²	41.4	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-60.3	-46.7	172.9	168.7	0	0	0	0	111.4	V88 V89 L90 R95 N96 Q97	V88-S92 PolarHBondContact O-N 2.92Å; V89-S92 WeakPolarHBondContact O-CB 3.4Å; V89-S92 PolarHBondContact O-N 3.33Å; L90-S92 VanDerWaalsContact C-N 3.35Å; S92-R95 PolarHBondContact O-N 2.91Å; S92-N96 PolarHBondContact O-N 3.07Å; S92-Q97 CarbonylContact C-O 3.5Å; S92-Q97 WeakPolarHBondContact CA-O 3.42Å; S92-Q97 VanDerWaalsContact CB-O 3.32Å; S92-Q97 WeakPolarHBondContact CB-O 3.43Å; S92-Q97 PolarHBondContact O-N 2.88Å; S92-Q97 VanDerWaalsContact O-N 3.16Å; S92-Q97 PolarHBondContact OG-O 2.95Å
93	Y	87.8	Confident	88.1	Confident	17 Å²	17	42.1 Å²	42.1	7%	0.067	25%	0.245	C	C	.	.	H	α-helix	trans	-63.5	-41.9	173.3	-77.6	-72.8	0	0	0	113	L19 E23 P25 V89 L90 R95 N96 T185	L19-Y93 HydrophobicContact CD2-CD1 3.74Å; L19-Y93 HydrophobicContact CD2-CE1 3.65Å; E23-Y93 HydrophobicContact CB-CE1 4.25Å; P25-Y93 HydrophobicContact CB-CD1 4.12Å; P25-Y93 HydrophobicContact CB-CD2 4.03Å; P25-Y93 HydrophobicContact CB-CG 3.78Å; V89-Y93 HydrophobicContact CG1-CD2 3.95Å; V89-Y93 HydrophobicContact CG1-CE2 3.66Å; V89-Y93 VanDerWaalsContact O-CD2 3.23Å; V89-Y93 WeakPolarHBondContact O-CD2 3.35Å; V89-Y93 PolarHBondContact O-N 3.44Å; V89-Y93 VanDerWaalsContact O-N 3.11Å; L90-Y93 PolarHBondContact O-N 3.41Å; Y93-R95 VanDerWaalsContact C-N 3.28Å; Y93-R95 PolarHBondContact O-N 3.34Å; Y93-N96 PolarHBondContact O-N 3.43Å; Y93-N96 PolarHBondContact O-OD1 3.16Å; Y93-T185 HydrophobicContact CD2-CG2 4.18Å; Y93-T185 HydrophobicContact CE1-CG2 4.11Å; Y93-T185 HydrophobicContact CE2-CG2 3.7Å; Y93-T185 PolarHBondContact OH-OG1 3.3Å
94	A	87.6	Confident	87.7	Confident	84 Å²	84	44.1 Å²	44.1	69%	0.694	26%	0.257	S	S	*	.	H	α-helix	trans	-66.2	-30.4	-178.6	0	0	0	0	0	113	L90 A91	L90-A94 WeakPolarHBondContact O-CB 3.39Å; L90-A94 PolarHBondContact O-N 3.14Å; A91-A94 PolarHBondContact O-N 3.44Å
95	R	87.1	Confident	87.1	Confident	164 Å²	164	47.8 Å²	47.8	62%	0.619	27%	0.272	S	S	*	.	H	α-helix	trans	-96.5	-1.9	178.5	-65.3	-170.1	177.8	-163.4	-1.1	113.8	A91 S92 Y93 Q97	A91-R95 PolarHBondContact O-N 3.2Å; S92-R95 PolarHBondContact O-N 2.91Å; Y93-R95 VanDerWaalsContact C-N 3.28Å; Y93-R95 PolarHBondContact O-N 3.34Å; R95-Q97 HydrophobicContact CB-CB 4.27Å; R95-Q97 HydrophobicContact CB-CG 4.34Å; R95-Q97 WeakPolarHBondContact O-CG 3.49Å; R95-Q97 PolarHBondContact O-N 3.15Å; R95-Q97 VanDerWaalsContact O-N 3.14Å
96	N	87.2	Confident	86.7	Confident	103 Å²	103	48.6 Å²	48.6	55%	0.551	28%	0.28	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.5	28.8	-171.9	-68	-32.3	0	0	0	113.9	L19 S92 Y93	L19-N96 VanDerWaalsContact CD1-C 3.45Å; L19-N96 PolarHBondContact N-O 3.27Å; L19-N96 VanDerWaalsContact N-O 3.14Å; S92-N96 PolarHBondContact O-N 3.07Å; Y93-N96 PolarHBondContact O-N 3.43Å; Y93-N96 PolarHBondContact O-OD1 3.16Å
97	Q	87.4	Confident	86.6	Confident	47 Å²	47	54.8 Å²	54.8	22%	0.22	30%	0.3	C	S	.	.	B	Isolated β-bridge	trans	-115.4	142.7	-177.3	-77.4	176.5	-23.5	0	0	109.7	Q17 W18 L19 S92 R95 A101	Q17-Q97 WeakPolarHBondContact O-CA 3.45Å; W18-Q97 HydrophobicContact CE3-CG 4.13Å; W18-Q97 HydrophobicContact CZ3-CG 3.9Å; L19-Q97 VanDerWaalsContact CD1-C 3.48Å; L19-Q97 VanDerWaalsContact CD1-O 3.23Å; L19-Q97 WeakPolarHBondContact CD1-O 3.36Å; S92-Q97 CarbonylContact C-O 3.5Å; S92-Q97 WeakPolarHBondContact CA-O 3.42Å; S92-Q97 VanDerWaalsContact CB-O 3.32Å; S92-Q97 WeakPolarHBondContact CB-O 3.43Å; S92-Q97 PolarHBondContact O-N 2.88Å; S92-Q97 VanDerWaalsContact O-N 3.16Å; S92-Q97 PolarHBondContact OG-O 2.95Å; R95-Q97 HydrophobicContact CB-CB 4.27Å; R95-Q97 HydrophobicContact CB-CG 4.34Å; R95-Q97 WeakPolarHBondContact O-CG 3.49Å; R95-Q97 PolarHBondContact O-N 3.15Å; R95-Q97 VanDerWaalsContact O-N 3.14Å; Q97-A101 HydrophobicContact CB-CB 4.28Å
98	T	87.8	Confident	86.6	Confident	0 Å²	0	52.8 Å²	52.8	0%	0	29%	0.288	C	S	.	.			trans	-72.2	165.1	174.9	64.7	0	0	0	0	111.3	R16 Q17 V100 A101 L102 Q180 G184	R16-T98 WeakPolarHBondContact O-CB 3.29Å; R16-T98 VanDerWaalsContact O-CG2 3.23Å; R16-T98 WeakPolarHBondContact O-CG2 3.5Å; R16-T98 PolarHBondContact O-OG1 3.3Å; Q17-T98 WeakPolarHBondContact CA-OG1 3.43Å; Q17-T98 PolarHBondContact O-N 3.41Å; Q17-T98 PolarHBondContact O-OG1 3.26Å; T98-V100 PolarHBondContact O-N 2.9Å; T98-A101 PolarHBondContact O-N 2.87Å; T98-L102 PolarHBondContact O-N 3.4Å; T98-Q180 PolarHBondContact OG1-OE1 2.89Å; T98-G184 WeakPolarHBondContact CA-O 3.34Å; T98-G184 WeakPolarHBondContact CB-O 3.46Å
99	L	85.3	Confident	86.5	Confident	0 Å²	0	51.8 Å²	51.8	0%	0	28%	0.282	C	S	.	.	T	Hydrogen-bonded Turn	trans	-59.6	-31.9	179.6	-79.7	168.6	0	0	0	113.1	V88 A101 A108 C109 F112 G184 T185 C187	V88-L99 HydrophobicContact CG1-CD2 3.47Å; V88-L99 VanDerWaalsContact CG1-CD2 3.47Å; L99-A101 VanDerWaalsContact C-N 3.35Å; L99-A108 WeakPolarHBondContact O-CB 3.49Å; L99-C109 HydrophobicContact CB-CB 4.23Å; L99-F112 HydrophobicContact CD1-CB 4.36Å; L99-F112 HydrophobicContact CD1-CD1 3.99Å; L99-F112 HydrophobicContact CD1-CD2 4.39Å; L99-F112 HydrophobicContact CD1-CE1 4.38Å; L99-F112 HydrophobicContact CD1-CG 3.99Å; L99-F112 HydrophobicContact CD2-CB 4.43Å; L99-G184 PolarHBondContact N-O 3.28Å; L99-T185 VanDerWaalsContact CD1-O 3.25Å; L99-T185 WeakPolarHBondContact CD1-O 3.5Å; L99-C187 HydrophobicContact CD1-CB 4.03Å
100	V	85.8	Confident	86.5	Confident	29 Å²	29	53.7 Å²	53.7	18%	0.176	29%	0.294	C	S	.	.	T	Hydrogen-bonded Turn	trans	-68.2	-35.3	175.7	167.7	0	0	0	0	111.5	T98 C109 Q180	T98-V100 PolarHBondContact O-N 2.9Å; V100-C109 HydrophobicContact CG2-CB 4.07Å; V100-Q180 HydrophobicContact CG2-CB 4Å; V100-Q180 VanDerWaalsContact CG2-OE1 3.25Å
101	A	85.5	Confident	86.7	Confident	29 Å²	29	55.8 Å²	55.8	24%	0.24	30%	0.299	C	S	.	.	T	Hydrogen-bonded Turn	trans	-85.9	-18.3	-180	0	0	0	0	0	114.2	Q17 Q97 T98 L99 A103	Q17-A101 HydrophobicContact CB-CB 3.78Å; Q17-A101 HydrophobicContact CG-CB 4.12Å; Q17-A101 VanDerWaalsContact O-CB 3.3Å; Q17-A101 WeakPolarHBondContact O-CB 3.18Å; Q97-A101 HydrophobicContact CB-CB 4.28Å; T98-A101 PolarHBondContact O-N 2.87Å; L99-A101 VanDerWaalsContact C-N 3.35Å; A101-A103 VanDerWaalsContact C-N 3.29Å; A101-A103 PolarHBondContact O-N 3.34Å
102	L	86.4	Confident	86.8	Confident	35 Å²	35	54 Å²	54	18%	0.183	28%	0.284	C	S	.	.	S	Bend	trans	-68.2	-26.7	-174.6	-169.8	64.2	0	0	0	113.4	V88 A91 T98 A108	V88-L102 HydrophobicContact CG1-CD2 4.15Å; A91-L102 HydrophobicContact CB-CD2 4.29Å; T98-L102 PolarHBondContact O-N 3.4Å; L102-A108 HydrophobicContact CB-CB 4.25Å; L102-A108 HydrophobicContact CD2-CB 4.45Å
103	A	85.8	Confident	86.8	Confident	27 Å²	27	54 Å²	54	22%	0.223	28%	0.284	C	S	.	.	S	Bend	trans	-141.8	147.9	177.1	0	0	0	0	0	110.7	A101 S106 R107 A108	A101-A103 VanDerWaalsContact C-N 3.29Å; A101-A103 PolarHBondContact O-N 3.34Å; A103-S106 PolarHBondContact O-N 2.95Å; A103-R107 HydrophobicContact CB-CB 4.34Å; A103-A108 HydrophobicContact CB-CB 3.73Å
104	P	81.9	Confident	87	Confident	100 Å²	100	55.4 Å²	55.4	65%	0.649	29%	0.29	S	S	*	.	G	3₁₀ helix	trans	-57.8	150	177.2	24.4	-33.5	0	0	0	111.2	S106 R107	P104-S106 PolarHBondContact O-N 2.9Å; P104-R107 VanDerWaalsContact O-CG 3.32Å; P104-R107 WeakPolarHBondContact O-CG 3.36Å; P104-R107 PolarHBondContact O-N 3.25Å
105	E	78.8	Confident	87.2	Confident	148 Å²	148	51.6 Å²	51.6	69%	0.692	26%	0.259	S	S	*	.	G	3₁₀ helix	trans	56.9	27.3	178.8	-53.8	173	163.5	0	0	114.1	R107	E105-R107 HydrophobicContact CB-CG 4.33Å; E105-R107 PolarHBondContact O-N 3.49Å; E105-R107 IonicContact OE2-CZ 3.53Å; E105-R107 VanDerWaalsContact OE2-CZ 3.29Å; E105-R107 IonicContact OE2-NE 3.29Å; E105-R107 PolarHBondContact OE2-NE 2.84Å; E105-R107 IonicContact OE2-NH2 3.96Å; E105-R107 PolarHBondContact OE2-NH2 3.41Å
106	S	83.1	Confident	87.3	Confident	42 Å²	42	44.2 Å²	44.2	29%	0.294	23%	0.232	S	C	.	.	G	3₁₀ helix	trans	59.1	21	-179.6	-49.4	0	0	0	0	114.1	A103 P104 A108 C109 T110	A103-S106 PolarHBondContact O-N 2.95Å; P104-S106 PolarHBondContact O-N 2.9Å; S106-A108 VanDerWaalsContact C-N 3.25Å; S106-A108 PolarHBondContact O-N 3.37Å; S106-C109 WeakPolarHBondContact O-CA 3.28Å; S106-C109 VanDerWaalsContact O-CB 3.26Å; S106-C109 WeakPolarHBondContact O-CB 3.49Å; S106-C109 PolarHBondContact O-N 3.4Å; S106-T110 PolarHBondContact O-N 2.86Å; S106-T110 PolarHBondContact O-OG1 3.49Å
107	R	87.1	Confident	87.4	Confident	153 Å²	153	39.3 Å²	39.3	58%	0.577	21%	0.205	S	C	*	.	H	α-helix	trans	-58.8	-35	-175.9	-71.8	176.8	-172.7	-167.7	3.7	113.2	A103 P104 E105 T110 Y111	A103-R107 HydrophobicContact CB-CB 4.34Å; P104-R107 VanDerWaalsContact O-CG 3.32Å; P104-R107 WeakPolarHBondContact O-CG 3.36Å; P104-R107 PolarHBondContact O-N 3.25Å; E105-R107 HydrophobicContact CB-CG 4.33Å; E105-R107 PolarHBondContact O-N 3.49Å; E105-R107 IonicContact OE2-CZ 3.53Å; E105-R107 VanDerWaalsContact OE2-CZ 3.29Å; E105-R107 IonicContact OE2-NE 3.29Å; E105-R107 PolarHBondContact OE2-NE 2.84Å; E105-R107 IonicContact OE2-NH2 3.96Å; E105-R107 PolarHBondContact OE2-NH2 3.41Å; R107-T110 PolarHBondContact O-N 2.98Å; R107-Y111 VanDerWaalsContact O-CB 3.24Å; R107-Y111 WeakPolarHBondContact O-CB 3.12Å; R107-Y111 PolarHBondContact O-N 3.21Å
108	A	88.9	Confident	87.6	Confident	13 Å²	13	38.6 Å²	38.6	11%	0.107	20%	0.202	C	C	.	.	H	α-helix	trans	-66.2	-38.3	176.1	0	0	0	0	0	111.8	L99 L102 A103 S106 F112	L99-A108 WeakPolarHBondContact O-CB 3.49Å; L102-A108 HydrophobicContact CB-CB 4.25Å; L102-A108 HydrophobicContact CD2-CB 4.45Å; A103-A108 HydrophobicContact CB-CB 3.73Å; S106-A108 VanDerWaalsContact C-N 3.25Å; S106-A108 PolarHBondContact O-N 3.37Å; A108-F112 WeakPolarHBondContact O-CB 2.94Å; A108-F112 PolarHBondContact O-N 3.43Å
109	C	89.1	Confident	87.8	Confident	4 Å²	4	39.5 Å²	39.5	3%	0.027	21%	0.206	C	C	.	.	H	α-helix	trans	-65.6	-46.2	174.6	-175.5	0	0	0	0	111.7	L99 V100 S106 F112 A113 C187	L99-C109 HydrophobicContact CB-CB 4.23Å; V100-C109 HydrophobicContact CG2-CB 4.07Å; S106-C109 WeakPolarHBondContact O-CA 3.28Å; S106-C109 VanDerWaalsContact O-CB 3.26Å; S106-C109 WeakPolarHBondContact O-CB 3.49Å; S106-C109 PolarHBondContact O-N 3.4Å; C109-F112 PolarHBondContact O-N 3.49Å; C109-A113 WeakPolarHBondContact O-CB 3.23Å; C109-A113 PolarHBondContact O-N 3.49Å; C109-C187 WeakPolarHBondContact CA-SG 3.35Å; C109-C187 HydrophobicContact CB-CB 3.91Å; C109-C187 WeakPolarHBondContact CB-SG 3.21Å; C109-C187 WeakPolarHBondContact O-CB 3.32Å; C109-C187 WeakPolarHBondContact SG-CB 3.35Å; C109-C187 CovalentContact SG-SG 2.02Å; C109-C187 PolarHBondContact SG-SG 3Å
110	T	88.9	Confident	88	Confident	46 Å²	46	40 Å²	40	28%	0.282	21%	0.21	S	C	.	.	H	α-helix	trans	-62.5	-47.1	176	-52.4	0	0	0	0	111.8	S106 R107 F112 A113 F114 L172 Y178	S106-T110 PolarHBondContact O-N 2.86Å; S106-T110 PolarHBondContact O-OG1 3.49Å; R107-T110 PolarHBondContact O-N 2.98Å; T110-F112 PolarHBondContact O-N 3.2Å; T110-A113 PolarHBondContact O-N 2.96Å; T110-F114 VanDerWaalsContact O-CB 3.22Å; T110-F114 WeakPolarHBondContact O-CB 3.29Å; T110-F114 PolarHBondContact O-N 3.1Å; T110-L172 HydrophobicContact CG2-CD2 3.65Å; T110-Y178 HydrophobicContact CG2-CD2 3.93Å; T110-Y178 HydrophobicContact CG2-CE2 4.05Å
111	Y	90.8	Very high	88.2	Confident	93 Å²	93	38.7 Å²	38.7	37%	0.365	20%	0.201	S	C	.	.	H	α-helix	trans	-58	-47.4	175.2	166.9	-94.3	0	0	0	111.4	L84 V88 R107 F114 A115	L84-Y111 WeakPolarHBondContact CB-OH 3.24Å; L84-Y111 WeakPolarHBondContact O-CE1 3.29Å; L84-Y111 PolarHBondContact O-OH 3.42Å; L84-Y111 VanDerWaalsContact O-OH 3.04Å; V88-Y111 HydrophobicContact CG2-CD1 4.27Å; V88-Y111 HydrophobicContact CG2-CE1 3.82Å; R107-Y111 VanDerWaalsContact O-CB 3.24Å; R107-Y111 WeakPolarHBondContact O-CB 3.12Å; R107-Y111 PolarHBondContact O-N 3.21Å; Y111-F114 PolarHBondContact O-N 3.03Å; Y111-A115 VanDerWaalsContact O-CB 3.23Å; Y111-A115 WeakPolarHBondContact O-CB 3.33Å; Y111-A115 PolarHBondContact O-N 2.85Å
112	F	91.2	Very high	88.6	Confident	0 Å²	0	37.3 Å²	37.3	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-61.8	-46.7	-179.4	179.3	-88.4	0	0	0	111.6	I85 V89 L99 A108 C109 T110 A115 M116 W186 C187	I85-F112 HydrophobicContact CG2-CD2 3.8Å; I85-F112 HydrophobicContact CG2-CE2 3.25Å; I85-F112 HydrophobicContact CG2-CZ 3.93Å; V89-F112 HydrophobicContact CG2-CD2 4.19Å; V89-F112 HydrophobicContact CG2-CE2 3.34Å; V89-F112 HydrophobicContact CG2-CZ 3.99Å; L99-F112 HydrophobicContact CD1-CB 4.36Å; L99-F112 HydrophobicContact CD1-CD1 3.99Å; L99-F112 HydrophobicContact CD1-CD2 4.39Å; L99-F112 HydrophobicContact CD1-CE1 4.38Å; L99-F112 HydrophobicContact CD1-CG 3.99Å; L99-F112 HydrophobicContact CD2-CB 4.43Å; A108-F112 WeakPolarHBondContact O-CB 2.94Å; A108-F112 PolarHBondContact O-N 3.43Å; C109-F112 PolarHBondContact O-N 3.49Å; T110-F112 PolarHBondContact O-N 3.2Å; F112-A115 PolarHBondContact O-N 2.79Å; F112-M116 HydrophobicContact CD1-CE 4.12Å; F112-M116 HydrophobicContact CE1-CE 3.31Å; F112-M116 HydrophobicContact CZ-CE 3.93Å; F112-M116 VanDerWaalsContact O-CB 3.3Å; F112-M116 WeakPolarHBondContact O-CB 3.28Å; F112-M116 PolarHBondContact O-N 3.27Å; F112-W186 HydrophobicContact CE1-CB 4.31Å; F112-W186 HydrophobicContact CE1-CD2 4.41Å; F112-W186 HydrophobicContact CE1-CE3 4.03Å; F112-W186 HydrophobicContact CZ-CD2 4.04Å; F112-W186 AromaticContact CZ-CE3 3.78Å; F112-W186 HydrophobicContact CZ-CE3 3.78Å; F112-W186 HydrophobicContact CZ-CG 4.46Å; F112-W186 HydrophobicContact CZ-CZ3 4.23Å; F112-C187 HydrophobicContact CD1-CB 3.94Å; F112-C187 VanDerWaalsContact CD1-N 3.35Å; F112-C187 VanDerWaalsContact CD1-O 3.23Å; F112-C187 WeakPolarHBondContact CD1-O 3.3Å; F112-C187 VanDerWaalsContact CE1-N 3.34Å; F112-C187 WeakPolarHBondContact CE1-O 3.36Å
113	A	89.8	Confident	88.7	Confident	0 Å²	0	35.7 Å²	35.7	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-66.4	-41.6	178.8	0	0	0	0	0	112.2	C109 T110 T117 Y178 C187	C109-A113 WeakPolarHBondContact O-CB 3.23Å; C109-A113 PolarHBondContact O-N 3.49Å; T110-A113 PolarHBondContact O-N 2.96Å; A113-T117 WeakPolarHBondContact O-CB 3.34Å; A113-T117 VanDerWaalsContact O-CG2 3.31Å; A113-T117 WeakPolarHBondContact O-CG2 3.16Å; A113-T117 PolarHBondContact O-N 3.27Å; A113-T117 PolarHBondContact O-OG1 3.28Å; A113-Y178 HydrophobicContact CB-CD1 3.31Å; A113-Y178 HydrophobicContact CB-CD2 4.31Å; A113-Y178 HydrophobicContact CB-CE1 3.64Å; A113-Y178 HydrophobicContact CB-CG 3.68Å; A113-C187 HydrophobicContact CB-CB 4.32Å
114	F	91	Very high	88.8	Confident	46 Å²	46	34.4 Å²	34.4	20%	0.202	17%	0.171	C	C	.	.	H	α-helix	trans	-61.7	-50.7	174.5	175.3	-90.8	0	0	0	111.5	T110 Y111 M116 T117 F118 L165 C168 L172	T110-F114 VanDerWaalsContact O-CB 3.22Å; T110-F114 WeakPolarHBondContact O-CB 3.29Å; T110-F114 PolarHBondContact O-N 3.1Å; Y111-F114 PolarHBondContact O-N 3.03Å; F114-M116 PolarHBondContact O-N 3.31Å; F114-T117 PolarHBondContact O-N 2.91Å; F114-T117 PolarHBondContact O-OG1 3.43Å; F114-F118 VanDerWaalsContact O-CB 3.27Å; F114-F118 WeakPolarHBondContact O-CB 3.36Å; F114-F118 PolarHBondContact O-N 3.44Å; F114-L165 HydrophobicContact CZ-CD1 3.73Å; F114-C168 HydrophobicContact CD2-CB 3.93Å; F114-C168 WeakPolarHBondContact CD2-O 3.5Å; F114-C168 HydrophobicContact CE2-CB 3.63Å; F114-C168 HydrophobicContact CZ-CB 4.33Å; F114-L172 HydrophobicContact CD2-CD1 4.01Å; F114-L172 HydrophobicContact CE2-CD1 4.13Å
115	A	91.4	Very high	89.3	Confident	4 Å²	4	30.9 Å²	30.9	3%	0.033	15%	0.146	C	C	.	.	H	α-helix	trans	-60.3	-47	179	0	0	0	0	0	110.9	I85 Y111 F112 T117 F118 F119	I85-A115 HydrophobicContact CD1-CB 4.4Å; I85-A115 HydrophobicContact CG1-CB 3.94Å; Y111-A115 VanDerWaalsContact O-CB 3.23Å; Y111-A115 WeakPolarHBondContact O-CB 3.33Å; Y111-A115 PolarHBondContact O-N 2.85Å; F112-A115 PolarHBondContact O-N 2.79Å; A115-T117 PolarHBondContact O-N 3.42Å; A115-F118 PolarHBondContact O-N 2.82Å; A115-F119 HydrophobicContact CB-CD2 4.25Å; A115-F119 HydrophobicContact CB-CE2 4.25Å; A115-F119 WeakPolarHBondContact O-CB 3.25Å; A115-F119 WeakPolarHBondContact O-CD2 3.17Å; A115-F119 PolarHBondContact O-N 2.92Å
116	M	89.4	Confident	89.8	Confident	9 Å²	9	23.9 Å²	23.9	4%	0.044	11%	0.114	C	C	.	.	H	α-helix	trans	-59.5	-46.9	179	-166	-148.4	-59.8	0	0	111.9	I85 F112 F114 S120 W186 F188 L301	I85-M116 HydrophobicContact CD1-CB 4.29Å; F112-M116 HydrophobicContact CD1-CE 4.12Å; F112-M116 HydrophobicContact CE1-CE 3.31Å; F112-M116 HydrophobicContact CZ-CE 3.93Å; F112-M116 VanDerWaalsContact O-CB 3.3Å; F112-M116 WeakPolarHBondContact O-CB 3.28Å; F112-M116 PolarHBondContact O-N 3.27Å; F114-M116 PolarHBondContact O-N 3.31Å; M116-S120 WeakPolarHBondContact O-CB 3.45Å; M116-S120 PolarHBondContact O-N 2.87Å; M116-W186 HydrophobicContact CE-CE3 3.68Å; M116-W186 HydrophobicContact CE-CZ3 3.97Å; M116-F188 HydrophobicContact CE-CD2 3.75Å; M116-F188 HydrophobicContact CE-CE2 4.49Å; M116-F188 HydrophobicContact SD-CD2 3.39Å; M116-F188 WeakPolarHBondContact SD-CD2 3.45Å; M116-F188 HydrophobicContact SD-CE2 3.54Å; M116-F188 VanDerWaalsContact SD-CE2 3.54Å; M116-F188 HydrophobicContact SD-CG 4.47Å; M116-L301 HydrophobicContact SD-CD2 4.15Å
117	T	89.6	Confident	89.9	Confident	0 Å²	0	22.4 Å²	22.4	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-65.4	-41.4	178.2	53.1	0	0	0	0	112.1	A113 F114 A115 L121 C168 F188 I189	A113-T117 WeakPolarHBondContact O-CB 3.34Å; A113-T117 VanDerWaalsContact O-CG2 3.31Å; A113-T117 WeakPolarHBondContact O-CG2 3.16Å; A113-T117 PolarHBondContact O-N 3.27Å; A113-T117 PolarHBondContact O-OG1 3.28Å; F114-T117 PolarHBondContact O-N 2.91Å; F114-T117 PolarHBondContact O-OG1 3.43Å; A115-T117 PolarHBondContact O-N 3.42Å; T117-L121 VanDerWaalsContact O-CB 3.29Å; T117-L121 WeakPolarHBondContact O-CB 3.4Å; T117-L121 PolarHBondContact O-N 3.36Å; T117-C168 VanDerWaalsContact C-SG 3.51Å; T117-C168 PolarHBondContact OG1-SG 3.25Å; T117-F188 HydrophobicContact CG2-CD2 4.22Å; T117-F188 HydrophobicContact CG2-CE2 3.41Å; T117-F188 VanDerWaalsContact CG2-CE2 3.41Å; T117-F188 HydrophobicContact CG2-CZ 3.82Å; T117-I189 HydrophobicContact CG2-CD1 3.9Å; T117-I189 HydrophobicContact CG2-CG1 4.25Å
118	F	92.6	Very high	90	Very high	32 Å²	32	17.8 Å²	17.8	14%	0.14	9%	0.087	C	C	.	.	H	α-helix	trans	-63.6	-52.8	179.4	172.1	-97.4	0	0	0	112.2	F114 A115 S120 L121 A122 Y161 L165 C168	F114-F118 VanDerWaalsContact O-CB 3.27Å; F114-F118 WeakPolarHBondContact O-CB 3.36Å; F114-F118 PolarHBondContact O-N 3.44Å; A115-F118 PolarHBondContact O-N 2.82Å; F118-S120 VanDerWaalsContact C-N 3.35Å; F118-S120 PolarHBondContact O-N 3.45Å; F118-L121 PolarHBondContact O-N 2.94Å; F118-A122 VanDerWaalsContact O-CB 3.26Å; F118-A122 WeakPolarHBondContact O-CB 3.24Å; F118-A122 PolarHBondContact O-N 3.45Å; F118-Y161 HydrophobicContact CE1-CD1 4.45Å; F118-Y161 HydrophobicContact CE2-CD1 4.48Å; F118-Y161 AromaticContact CZ-CD1 3.74Å; F118-Y161 HydrophobicContact CZ-CD1 3.74Å; F118-Y161 HydrophobicContact CZ-CE1 4.47Å; F118-L165 HydrophobicContact CE2-CB 4.14Å; F118-C168 WeakPolarHBondContact CA-SG 3.43Å; F118-C168 HydrophobicContact CB-CB 4.36Å; F118-C168 PolarHBondContact N-SG 2.82Å
119	F	91.5	Very high	90	Very high	19 Å²	19	17.9 Å²	17.9	8%	0.083	9%	0.087	C	C	.	.	H	α-helix	trans	-64.6	-41.3	180	-74.2	-65.4	0	0	0	111	T77 L80 L84 I85 A115 L121 A122 T123	T77-F119 HydrophobicContact CG2-CD1 3.82Å; T77-F119 HydrophobicContact CG2-CE1 4.31Å; L80-F119 HydrophobicContact CB-CE1 3.99Å; L80-F119 HydrophobicContact CB-CZ 4.28Å; L84-F119 HydrophobicContact CB-CE2 4.24Å; L84-F119 HydrophobicContact CD1-CE2 3.85Å; L84-F119 HydrophobicContact CD1-CZ 3.53Å; I85-F119 HydrophobicContact CD1-CD2 3.97Å; I85-F119 HydrophobicContact CG1-CD2 4.43Å; A115-F119 HydrophobicContact CB-CD2 4.25Å; A115-F119 HydrophobicContact CB-CE2 4.25Å; A115-F119 WeakPolarHBondContact O-CB 3.25Å; A115-F119 WeakPolarHBondContact O-CD2 3.17Å; A115-F119 PolarHBondContact O-N 2.92Å; F119-L121 PolarHBondContact O-N 3.49Å; F119-A122 PolarHBondContact O-N 3.3Å; F119-T123 WeakPolarHBondContact O-CB 3.49Å; F119-T123 PolarHBondContact O-N 2.91Å; F119-T123 PolarHBondContact O-OG1 3.23Å
120	S	89.3	Confident	89.7	Confident	12 Å²	12	17.8 Å²	17.8	8%	0.084	9%	0.086	C	C	.	.	H	α-helix	trans	-59.2	-50.2	175.6	-175.9	0	0	0	0	111.8	M116 F118 T123 M124 Y200	M116-S120 WeakPolarHBondContact O-CB 3.45Å; M116-S120 PolarHBondContact O-N 2.87Å; F118-S120 VanDerWaalsContact C-N 3.35Å; F118-S120 PolarHBondContact O-N 3.45Å; S120-T123 PolarHBondContact O-N 2.93Å; S120-M124 WeakPolarHBondContact O-CG 3.46Å; S120-M124 PolarHBondContact O-N 3.27Å; S120-Y200 WeakPolarHBondContact CB-OH 3.3Å; S120-Y200 PolarHBondContact OG-OH 3.02Å; S120-Y200 VanDerWaalsContact OG-OH 3.13Å
121	L	91.1	Very high	89.4	Confident	0 Å²	0	15.7 Å²	15.7	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-66.7	-41.2	-179.2	-176	55.8	0	0	0	112.5	T117 F118 F119 M124 L125 F167 Y200 L203 L204 L207	T117-L121 VanDerWaalsContact O-CB 3.29Å; T117-L121 WeakPolarHBondContact O-CB 3.4Å; T117-L121 PolarHBondContact O-N 3.36Å; F118-L121 PolarHBondContact O-N 2.94Å; F119-L121 PolarHBondContact O-N 3.49Å; L121-M124 PolarHBondContact O-N 3.44Å; L121-L125 HydrophobicContact CD1-CD1 4.3Å; L121-L125 HydrophobicContact CD1-CG 4.33Å; L121-L125 HydrophobicContact CG-CD1 4.15Å; L121-L125 WeakPolarHBondContact O-CB 3.38Å; L121-L125 WeakPolarHBondContact O-CG 3.33Å; L121-L125 PolarHBondContact O-N 3.28Å; L121-F167 HydrophobicContact CD2-CB 3.78Å; L121-F167 HydrophobicContact CD2-CD1 3.72Å; L121-F167 HydrophobicContact CD2-CG 3.82Å; L121-Y200 HydrophobicContact CB-CE2 4.39Å; L121-L203 HydrophobicContact CD1-CD2 3.67Å; L121-L203 HydrophobicContact CD1-CG 4.23Å; L121-L203 HydrophobicContact CD2-CD2 4.16Å; L121-L204 HydrophobicContact CD1-CD2 4.39Å; L121-L207 HydrophobicContact CD1-CD1 4.11Å
122	A	92.7	Very high	89.1	Confident	0 Å²	0	14.1 Å²	14.1	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-60.7	-47.1	176.2	0	0	0	0	0	111.6	T77 F118 F119 M124 L125 M126 I160 Y161 S164	T77-A122 HydrophobicContact CG2-CB 4.29Å; F118-A122 VanDerWaalsContact O-CB 3.26Å; F118-A122 WeakPolarHBondContact O-CB 3.24Å; F118-A122 PolarHBondContact O-N 3.45Å; F119-A122 PolarHBondContact O-N 3.3Å; A122-M124 VanDerWaalsContact C-N 3.33Å; A122-M124 PolarHBondContact O-N 3.47Å; A122-L125 PolarHBondContact O-N 2.8Å; A122-M126 WeakPolarHBondContact O-CB 3.38Å; A122-M126 PolarHBondContact O-N 3.46Å; A122-I160 HydrophobicContact CB-CG2 4.44Å; A122-Y161 HydrophobicContact CB-CD1 4.23Å; A122-Y161 HydrophobicContact CB-CE1 4.17Å; A122-S164 WeakPolarHBondContact CA-OG 3.28Å; A122-S164 PolarHBondContact N-OG 3.49Å
123	T	89.6	Confident	88.7	Confident	1 Å²	1	14.8 Å²	14.8	1%	0.006	8%	0.075	C	C	.	.	H	α-helix	trans	-60.1	-42.7	176.2	-64	0	0	0	0	111	L74 D78 F119 S120 M126 L127	L74-T123 HydrophobicContact CD1-CG2 3.75Å; D78-T123 PolarHBondContact OD1-OG1 2.87Å; F119-T123 WeakPolarHBondContact O-CB 3.49Å; F119-T123 PolarHBondContact O-N 2.91Å; F119-T123 PolarHBondContact O-OG1 3.23Å; S120-T123 PolarHBondContact O-N 2.93Å; T123-M126 WeakPolarHBondContact O-CB 3.28Å; T123-M126 PolarHBondContact O-N 2.96Å; T123-L127 HydrophobicContact CG2-CD1 4.13Å; T123-L127 WeakPolarHBondContact O-CG 3.36Å; T123-L127 PolarHBondContact O-N 3.37Å
124	M	87.4	Confident	88.1	Confident	0 Å²	0	15.6 Å²	15.6	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-63.5	-44.5	177.8	-61	-112.5	167.4	0	0	112.6	S120 L121 A122 M126 L127 F128 L204 L207 F273 S277 L304	S120-M124 WeakPolarHBondContact O-CG 3.46Å; S120-M124 PolarHBondContact O-N 3.27Å; L121-M124 PolarHBondContact O-N 3.44Å; A122-M124 VanDerWaalsContact C-N 3.33Å; A122-M124 PolarHBondContact O-N 3.47Å; M124-M126 VanDerWaalsContact C-N 3.33Å; M124-L127 PolarHBondContact O-N 3.17Å; M124-F128 PolarHBondContact O-N 2.93Å; M124-L204 HydrophobicContact CB-CD2 4.47Å; M124-L204 HydrophobicContact CE-CD2 4.38Å; M124-L204 HydrophobicContact CG-CD2 3.91Å; M124-L204 HydrophobicContact SD-CD2 3.68Å; M124-L207 HydrophobicContact CB-CD1 3.92Å; M124-F273 HydrophobicContact CB-CE2 4.13Å; M124-F273 HydrophobicContact CB-CZ 4.08Å; M124-F273 HydrophobicContact CE-CD2 4.29Å; M124-F273 HydrophobicContact CE-CE2 3.55Å; M124-F273 HydrophobicContact CE-CZ 4.11Å; M124-F273 HydrophobicContact CG-CE2 3.71Å; M124-F273 HydrophobicContact CG-CZ 3.97Å; M124-F273 HydrophobicContact SD-CD2 4.27Å; M124-F273 HydrophobicContact SD-CE1 4.29Å; M124-F273 HydrophobicContact SD-CE2 3.09Å; M124-F273 WeakPolarHBondContact SD-CE2 3.2Å; M124-F273 HydrophobicContact SD-CZ 3.1Å; M124-F273 WeakPolarHBondContact SD-CZ 3.36Å; M124-S277 WeakPolarHBondContact CE-OG 3.33Å; M124-L304 HydrophobicContact CE-CD1 3.67Å
125	L	91.9	Very high	87.4	Confident	26 Å²	26	16.4 Å²	16.4	14%	0.136	8%	0.08	C	C	.	.	H	α-helix	trans	-66.3	-35.8	176.4	-75.2	171.1	0	0	0	111.9	L121 A122 F128 A129 I160 V163 L207	L121-L125 HydrophobicContact CD1-CD1 4.3Å; L121-L125 HydrophobicContact CD1-CG 4.33Å; L121-L125 HydrophobicContact CG-CD1 4.15Å; L121-L125 WeakPolarHBondContact O-CB 3.38Å; L121-L125 WeakPolarHBondContact O-CG 3.33Å; L121-L125 PolarHBondContact O-N 3.28Å; A122-L125 PolarHBondContact O-N 2.8Å; L125-F128 PolarHBondContact O-N 2.85Å; L125-A129 WeakPolarHBondContact O-CB 3.48Å; L125-A129 PolarHBondContact O-N 3.36Å; L125-I160 HydrophobicContact CB-CB 4.39Å; L125-I160 HydrophobicContact CB-CD1 4.43Å; L125-I160 HydrophobicContact CB-CG1 4.06Å; L125-I160 HydrophobicContact CB-CG2 3.63Å; L125-I160 HydrophobicContact CD1-CG2 4.15Å; L125-V163 HydrophobicContact CD1-CB 4.41Å; L125-V163 HydrophobicContact CD1-CG1 4.08Å; L125-L207 HydrophobicContact CD2-CD1 4.04Å; L125-L207 HydrophobicContact CD2-CD2 3.78Å; L125-L207 HydrophobicContact CG-CD1 4.25Å
126	M	88.9	Confident	86.8	Confident	1 Å²	1	17.7 Å²	17.7	1%	0.005	9%	0.086	C	C	.	.	H	α-helix	trans	-64.4	-43.6	174	-161.7	73.5	75.6	0	0	111.3	L70 E73 L74 A122 T123 M124 F128 A129 M130 L157 I160	L70-M126 HydrophobicContact CB-SD 4.37Å; L70-M126 HydrophobicContact CD2-SD 3.58Å; L70-M126 VanDerWaalsContact CD2-SD 3.58Å; E73-M126 HydrophobicContact CB-CE 3.85Å; E73-M126 HydrophobicContact CB-SD 4.46Å; E73-M126 HydrophobicContact CG-CE 3.55Å; L74-M126 HydrophobicContact CB-CG 4.1Å; L74-M126 HydrophobicContact CD1-CB 3.88Å; L74-M126 HydrophobicContact CD1-CG 3.95Å; A122-M126 WeakPolarHBondContact O-CB 3.38Å; A122-M126 PolarHBondContact O-N 3.46Å; T123-M126 WeakPolarHBondContact O-CB 3.28Å; T123-M126 PolarHBondContact O-N 2.96Å; M124-M126 VanDerWaalsContact C-N 3.33Å; M126-F128 VanDerWaalsContact C-N 3.35Å; M126-F128 PolarHBondContact O-N 3.43Å; M126-A129 PolarHBondContact O-N 2.99Å; M126-M130 HydrophobicContact CG-CE 4.45Å; M126-M130 WeakPolarHBondContact O-CG 3.27Å; M126-M130 PolarHBondContact O-N 3.1Å; M126-L157 HydrophobicContact CE-CD2 3.75Å; M126-L157 HydrophobicContact SD-CD2 3.6Å; M126-I160 HydrophobicContact SD-CD1 3.98Å
127	L	85.7	Confident	86	Confident	11 Å²	11	18.2 Å²	18.2	6%	0.058	9%	0.09	C	C	.	.	H	α-helix	trans	-61.6	-41.9	175	-71.8	164.5	0	0	0	112	L74 T123 M124 M130 A131 M269 F273	L74-L127 HydrophobicContact CD1-CG 4.29Å; L74-L127 HydrophobicContact CD2-CD2 4.46Å; T123-L127 HydrophobicContact CG2-CD1 4.13Å; T123-L127 WeakPolarHBondContact O-CG 3.36Å; T123-L127 PolarHBondContact O-N 3.37Å; M124-L127 PolarHBondContact O-N 3.17Å; L127-M130 HydrophobicContact CB-CE 4.39Å; L127-M130 HydrophobicContact CD2-CE 3.5Å; L127-M130 HydrophobicContact CG-CE 4.03Å; L127-M130 PolarHBondContact O-N 3.45Å; L127-A131 WeakPolarHBondContact O-CB 3.29Å; L127-A131 PolarHBondContact O-N 3.38Å; L127-M269 HydrophobicContact CD2-CE 3.69Å; L127-F273 HydrophobicContact CD1-CB 4.36Å; L127-F273 HydrophobicContact CD1-CD2 3.23Å; L127-F273 HydrophobicContact CD1-CE2 3.42Å; L127-F273 VanDerWaalsContact CD1-CE2 3.42Å; L127-F273 HydrophobicContact CD1-CG 3.93Å; L127-F273 HydrophobicContact CD1-CZ 4.31Å
128	F	88.6	Confident	85	Confident	57 Å²	57	19.1 Å²	19.1	25%	0.25	10%	0.095	C	C	.	.	H	α-helix	trans	-61.6	-47	171.8	173.9	-111.9	0	0	0	112.6	M124 L125 M126 M130 A131 L132 L207 A210 V211	M124-F128 PolarHBondContact O-N 2.93Å; L125-F128 PolarHBondContact O-N 2.85Å; M126-F128 VanDerWaalsContact C-N 3.35Å; M126-F128 PolarHBondContact O-N 3.43Å; F128-M130 VanDerWaalsContact C-N 3.3Å; F128-M130 PolarHBondContact O-N 2.97Å; F128-A131 PolarHBondContact O-N 3.33Å; F128-L132 HydrophobicContact CE1-CD2 4.29Å; F128-L132 HydrophobicContact CZ-CD2 4.16Å; F128-L132 WeakPolarHBondContact O-CB 3.47Å; F128-L132 PolarHBondContact O-N 3.12Å; F128-L207 HydrophobicContact CB-CD2 4Å; F128-L207 HydrophobicContact CD1-CD2 4.27Å; F128-L207 HydrophobicContact CG-CD2 4.07Å; F128-A210 HydrophobicContact CD2-CB 3.96Å; F128-A210 HydrophobicContact CE2-CB 3.72Å; F128-V211 HydrophobicContact CB-CG2 3.89Å; F128-V211 HydrophobicContact CD2-CG2 4.18Å
129	A	88.8	Confident	83.9	Confident	14 Å²	14	18.4 Å²	18.4	12%	0.116	10%	0.097	C	C	.	.	H	α-helix	trans	-60.1	-39.8	177.2	0	0	0	0	0	112.1	L70 L125 M126 L132 E133 V156 I160	L70-A129 HydrophobicContact CD1-CB 4.46Å; L70-A129 HydrophobicContact CD2-CB 4.31Å; L125-A129 WeakPolarHBondContact O-CB 3.48Å; L125-A129 PolarHBondContact O-N 3.36Å; M126-A129 PolarHBondContact O-N 2.99Å; A129-L132 PolarHBondContact O-N 2.92Å; A129-E133 WeakPolarHBondContact O-CB 3.26Å; A129-E133 PolarHBondContact O-N 2.86Å; A129-V156 HydrophobicContact CB-CG1 3.96Å; A129-I160 HydrophobicContact CB-CD1 4Å
130	M	83.9	Confident	82.8	Confident	2 Å²	2	22 Å²	22	1%	0.01	11%	0.114	C	C	.	.	H	α-helix	trans	-64.9	-43.9	174.6	-72.7	-173	-66.7	0	0	112.4	L70 V71 L74 M126 L127 F128 L132 E133 R134 L266 M269	L70-M130 HydrophobicContact CB-CG 3.51Å; L70-M130 HydrophobicContact CB-SD 4.08Å; L70-M130 HydrophobicContact CD1-CG 3.84Å; L70-M130 HydrophobicContact CG-CG 4.26Å; V71-M130 HydrophobicContact CB-SD 4.43Å; V71-M130 HydrophobicContact CG2-SD 3.53Å; V71-M130 VanDerWaalsContact CG2-SD 3.53Å; L74-M130 HydrophobicContact CD1-CE 4.21Å; L74-M130 HydrophobicContact CD2-CE 3.83Å; L74-M130 HydrophobicContact CG-CE 4.45Å; M126-M130 HydrophobicContact CG-CE 4.45Å; M126-M130 WeakPolarHBondContact O-CG 3.27Å; M126-M130 PolarHBondContact O-N 3.1Å; L127-M130 HydrophobicContact CB-CE 4.39Å; L127-M130 HydrophobicContact CD2-CE 3.5Å; L127-M130 HydrophobicContact CG-CE 4.03Å; L127-M130 PolarHBondContact O-N 3.45Å; F128-M130 VanDerWaalsContact C-N 3.3Å; F128-M130 PolarHBondContact O-N 2.97Å; M130-L132 VanDerWaalsContact C-N 3.33Å; M130-L132 PolarHBondContact O-N 3.48Å; M130-E133 PolarHBondContact O-N 3.4Å; M130-R134 WeakPolarHBondContact O-CG 3.46Å; M130-R134 PolarHBondContact O-N 2.97Å; M130-L266 HydrophobicContact CB-CD2 4.28Å; M130-M269 HydrophobicContact CE-CE 4.12Å
131	A	81.8	Confident	82	Confident	2 Å²	2	24.8 Å²	24.8	2%	0.017	13%	0.131	C	C	.	.	H	α-helix	trans	-63.7	-39.9	176.4	0	0	0	0	0	111.7	L127 F128 R134 Y135 V211 C214	L127-A131 WeakPolarHBondContact O-CB 3.29Å; L127-A131 PolarHBondContact O-N 3.38Å; F128-A131 PolarHBondContact O-N 3.33Å; A131-R134 PolarHBondContact O-N 2.97Å; A131-Y135 WeakPolarHBondContact O-CB 3.32Å; A131-Y135 PolarHBondContact O-N 3.24Å; A131-V211 HydrophobicContact CB-CG1 4.17Å; A131-C214 HydrophobicContact CB-CB 4.06Å
132	L	85.1	Confident	81.1	Confident	61 Å²	61	33.1 Å²	33.1	32%	0.319	16%	0.164	S	C	.	.	H	α-helix	trans	-69.1	-42.5	178.3	-175.1	62.7	0	0	0	112.3	F128 A129 M130 R134 Y135 L136	F128-L132 HydrophobicContact CE1-CD2 4.29Å; F128-L132 HydrophobicContact CZ-CD2 4.16Å; F128-L132 WeakPolarHBondContact O-CB 3.47Å; F128-L132 PolarHBondContact O-N 3.12Å; A129-L132 PolarHBondContact O-N 2.92Å; M130-L132 VanDerWaalsContact C-N 3.33Å; M130-L132 PolarHBondContact O-N 3.48Å; L132-R134 PolarHBondContact O-N 2.88Å; L132-Y135 HydrophobicContact CD1-CD1 4.2Å; L132-Y135 PolarHBondContact O-N 3Å; L132-L136 HydrophobicContact CD1-CD1 4.33Å; L132-L136 HydrophobicContact CD1-CG 4.26Å; L132-L136 HydrophobicContact CG-CD1 4.12Å; L132-L136 HydrophobicContact CG-CG 4.45Å; L132-L136 WeakPolarHBondContact O-CB 3.29Å; L132-L136 VanDerWaalsContact O-CG 3.31Å; L132-L136 WeakPolarHBondContact O-CG 2.99Å; L132-L136 PolarHBondContact O-N 3.31Å
133	E	82.3	Confident	80.2	Confident	14 Å²	14	37.7 Å²	37.7	7%	0.065	18%	0.184	C	C	.	.	H	α-helix	trans	-53.8	-41.8	174.8	-174.4	-108	-168.6	0	0	110.7	L66 F67 L70 A129 M130 L136 S137 Y144	L66-E133 HydrophobicContact CB-CG 4.26Å; F67-E133 WeakPolarHBondContact CB-OE2 3.36Å; F67-E133 PolarHBondContact N-OE1 3.41Å; L70-E133 HydrophobicContact CD1-CB 4.42Å; A129-E133 WeakPolarHBondContact O-CB 3.26Å; A129-E133 PolarHBondContact O-N 2.86Å; M130-E133 PolarHBondContact O-N 3.4Å; E133-L136 PolarHBondContact O-N 2.61Å; E133-S137 WeakPolarHBondContact O-CB 3.37Å; E133-S137 PolarHBondContact O-N 2.85Å; E133-Y144 HydrophobicContact CG-CE2 4.18Å; E133-Y144 PolarHBondContact OE1-OH 3.26Å
134	R	77.3	Confident	79.4	Confident	16 Å²	16	40 Å²	40	6%	0.06	19%	0.193	C	C	.	.	H	α-helix	trans	-77.6	-38.7	-176.5	-66.8	-82	167.3	-154.3	1.9	113	F67 M130 A131 L132 L136 S137 I138 L266	F67-R134 VanDerWaalsContact CD1-NH2 3.3Å; F67-R134 HydrophobicContact CD2-CG 4.35Å; M130-R134 WeakPolarHBondContact O-CG 3.46Å; M130-R134 PolarHBondContact O-N 2.97Å; A131-R134 PolarHBondContact O-N 2.97Å; L132-R134 PolarHBondContact O-N 2.88Å; R134-L136 VanDerWaalsContact C-N 3.32Å; R134-S137 PolarHBondContact O-N 3.39Å; R134-S137 PolarHBondContact O-OG 3.36Å; R134-I138 WeakPolarHBondContact O-CB 3.49Å; R134-I138 PolarHBondContact O-N 2.8Å; R134-I138 VanDerWaalsContact O-N 3.12Å; R134-L266 HydrophobicContact CB-CD1 3.9Å; R134-L266 VanDerWaalsContact CD-CD1 3.42Å; R134-L266 HydrophobicContact CG-CD1 3.27Å; R134-L266 HydrophobicContact CG-CD2 4.39Å; R134-L266 HydrophobicContact CG-CG 4.44Å
135	Y	77.6	Confident	78.6	Confident	63 Å²	63	47.8 Å²	47.8	25%	0.247	23%	0.229	C	C	.	.	H	α-helix	trans	-57.7	-46.6	169.9	171.3	-103	0	0	0	111.5	A131 L132 G139 V218	A131-Y135 WeakPolarHBondContact O-CB 3.32Å; A131-Y135 PolarHBondContact O-N 3.24Å; L132-Y135 HydrophobicContact CD1-CD1 4.2Å; L132-Y135 PolarHBondContact O-N 3Å; Y135-G139 VanDerWaalsContact O-CA 3.32Å; Y135-G139 WeakPolarHBondContact O-CA 3.4Å; Y135-G139 PolarHBondContact O-N 3.27Å; Y135-V218 VanDerWaalsContact CA-CG2 3.43Å; Y135-V218 HydrophobicContact CD2-CG2 4.37Å
136	L	77.8	Confident	77.8	Confident	32 Å²	32	56.6 Å²	56.6	17%	0.168	26%	0.261	C	S	.	.	H	α-helix	trans	-70	-41.8	179.7	-66.5	174.5	0	0	0	112.1	L132 E133 R134 I138 H140 F143 Y144 V148	L132-L136 HydrophobicContact CD1-CD1 4.33Å; L132-L136 HydrophobicContact CD1-CG 4.26Å; L132-L136 HydrophobicContact CG-CD1 4.12Å; L132-L136 HydrophobicContact CG-CG 4.45Å; L132-L136 WeakPolarHBondContact O-CB 3.29Å; L132-L136 VanDerWaalsContact O-CG 3.31Å; L132-L136 WeakPolarHBondContact O-CG 2.99Å; L132-L136 PolarHBondContact O-N 3.31Å; E133-L136 PolarHBondContact O-N 2.61Å; R134-L136 VanDerWaalsContact C-N 3.32Å; L136-I138 PolarHBondContact O-N 2.67Å; L136-H140 CarbonylContact O-C 3.38Å; L136-H140 WeakPolarHBondContact O-CA 3.48Å; L136-H140 PolarHBondContact O-N 3.42Å; L136-H140 VanDerWaalsContact O-N 3.07Å; L136-F143 HydrophobicContact CD2-CD1 4.23Å; L136-F143 HydrophobicContact CD2-CE1 4.33Å; L136-Y144 HydrophobicContact CB-CD2 3.82Å; L136-V148 HydrophobicContact CD1-CG2 4.5Å
137	S	73.1	Confident	76.9	Confident	19 Å²	19	65.4 Å²	65.4	13%	0.133	29%	0.294	C	S	.	.	H	α-helix	trans	-63.9	-39.5	-178.2	78.4	0	0	0	0	112.4	E133 R134	E133-S137 WeakPolarHBondContact O-CB 3.37Å; E133-S137 PolarHBondContact O-N 2.85Å; R134-S137 PolarHBondContact O-N 3.39Å; R134-S137 PolarHBondContact O-OG 3.36Å
138	I	69.1	Low	76.1	Confident	19 Å²	19	67 Å²	67	10%	0.097	30%	0.304	C	S	.	.	H	α-helix	trans	-93.6	-41	-176	-67.1	158.1	0	0	0	112.2	R134 L136 V218 L222 L263	R134-I138 WeakPolarHBondContact O-CB 3.49Å; R134-I138 PolarHBondContact O-N 2.8Å; R134-I138 VanDerWaalsContact O-N 3.12Å; L136-I138 PolarHBondContact O-N 2.67Å; I138-V218 HydrophobicContact CD1-CG1 3.93Å; I138-L222 HydrophobicContact CG2-CD2 4.16Å; I138-L222 HydrophobicContact CG2-CG 4.31Å; I138-L263 HydrophobicContact CD1-CD1 3.65Å; I138-L263 HydrophobicContact CD1-CD2 3.16Å; I138-L263 HydrophobicContact CD1-CG 3.87Å
139	G	67.7	Low	75.4	Confident	18 Å²	18	67 Å²	67	19%	0.186	31%	0.312	C	S	.	.	H	α-helix	trans	-74.7	-39.4	-177.4	0	0	0	0	0	112.7	Y135	Y135-G139 VanDerWaalsContact O-CA 3.32Å; Y135-G139 WeakPolarHBondContact O-CA 3.4Å; Y135-G139 PolarHBondContact O-N 3.27Å
140	H	70.2	Confident	74.4	Confident	95 Å²	95	73.2 Å²	73.2	44%	0.44	33%	0.332	S	S	.	.			trans	-138.8	65.7	-172.1	-63.5	-66.1	0	0	0	112.6	L136 Y142 F143 Y144	L136-H140 CarbonylContact O-C 3.38Å; L136-H140 WeakPolarHBondContact O-CA 3.48Å; L136-H140 PolarHBondContact O-N 3.42Å; L136-H140 VanDerWaalsContact O-N 3.07Å; H140-Y142 VanDerWaalsContact C-N 3.3Å; H140-Y142 PolarHBondContact O-N 2.88Å; H140-F143 HydrophobicContact CB-CB 3.95Å; H140-F143 PolarHBondContact O-N 2.66Å; H140-Y144 PolarHBondContact O-N 3.38Å
141	P	71.8	Confident	74	Confident	69 Å²	69	77.4 Å²	77.4	45%	0.448	36%	0.362	S	S	.	.	H	α-helix	trans	-58.6	-37.4	-173.8	22.2	-33.9	0	0	0	113.6	Y144 Q145	P141-Y144 PolarHBondContact O-N 2.88Å; P141-Q145 WeakPolarHBondContact O-CB 3.33Å; P141-Q145 PolarHBondContact O-N 2.96Å
142	Y	71	Confident	73.8	Confident	176 Å²	176	79.2 Å²	79.2	69%	0.69	38%	0.38	S	S	*	.	H	α-helix	trans	-68.5	-33.6	177.4	-67.3	-73.6	0	0	0	113.4	H140 R146	H140-Y142 VanDerWaalsContact C-N 3.3Å; H140-Y142 PolarHBondContact O-N 2.88Å; Y142-R146 WeakPolarHBondContact O-CG 3.26Å; Y142-R146 PolarHBondContact O-N 3.32Å
143	F	74.1	Confident	73.4	Confident	96 Å²	96	76.9 Å²	76.9	42%	0.421	37%	0.371	S	S	.	.	H	α-helix	trans	-73.5	-44.4	175.5	-180	-93.6	0	0	0	110.3	L136 H140 Q145 R146 R147	L136-F143 HydrophobicContact CD2-CD1 4.23Å; L136-F143 HydrophobicContact CD2-CE1 4.33Å; H140-F143 HydrophobicContact CB-CB 3.95Å; H140-F143 PolarHBondContact O-N 2.66Å; F143-Q145 PolarHBondContact O-N 3.15Å; F143-R146 PolarHBondContact O-N 3.02Å; F143-R147 HydrophobicContact CD1-CB 4.37Å; F143-R147 HydrophobicContact CD2-CG 3.92Å; F143-R147 HydrophobicContact CE1-CB 4.06Å; F143-R147 HydrophobicContact CE1-CG 4.31Å; F143-R147 HydrophobicContact CE2-CB 4.29Å; F143-R147 HydrophobicContact CE2-CG 3.64Å; F143-R147 HydrophobicContact CG-CG 4.39Å; F143-R147 HydrophobicContact CZ-CB 4.02Å; F143-R147 HydrophobicContact CZ-CG 3.85Å; F143-R147 WeakPolarHBondContact O-CB 3.44Å; F143-R147 PolarHBondContact O-N 2.94Å
144	Y	73.8	Confident	73.4	Confident	50 Å²	50	80.7 Å²	80.7	20%	0.196	39%	0.391	C	S	.	.	H	α-helix	trans	-55.7	-49	176.9	-173.5	-97.7	0	0	0	111.4	E133 L136 H140 P141 R146 V148	E133-Y144 HydrophobicContact CG-CE2 4.18Å; E133-Y144 PolarHBondContact OE1-OH 3.26Å; L136-Y144 HydrophobicContact CB-CD2 3.82Å; H140-Y144 PolarHBondContact O-N 3.38Å; P141-Y144 PolarHBondContact O-N 2.88Å; Y144-R146 VanDerWaalsContact C-N 3.32Å; Y144-R146 PolarHBondContact O-N 3.47Å; Y144-V148 HydrophobicContact CD2-CB 3.85Å; Y144-V148 HydrophobicContact CD2-CG1 4.21Å; Y144-V148 HydrophobicContact CD2-CG2 3.64Å; Y144-V148 HydrophobicContact CE2-CB 3.88Å; Y144-V148 HydrophobicContact CE2-CG1 3.71Å; Y144-V148 HydrophobicContact CE2-CG2 3.97Å; Y144-V148 HydrophobicContact CG-CB 4.3Å; Y144-V148 HydrophobicContact CG-CG2 4.33Å; Y144-V148 WeakPolarHBondContact O-CA 3.16Å; Y144-V148 VanDerWaalsContact O-CB 3.29Å; Y144-V148 WeakPolarHBondContact O-CB 3.4Å; Y144-V148 PolarHBondContact O-N 3.46Å
145	Q	70.9	Confident	73.9	Confident	162 Å²	162	82.5 Å²	82.5	76%	0.757	41%	0.41	S	S	*	.	H	α-helix	trans	-65.6	-30	-179.3	-166.4	177.2	7.9	0	0	114	P141 F143	P141-Q145 WeakPolarHBondContact O-CB 3.33Å; P141-Q145 PolarHBondContact O-N 2.96Å; F143-Q145 PolarHBondContact O-N 3.15Å
146	R	73.9	Confident	74.5	Confident	212 Å²	212	82.1 Å²	82.1	80%	0.8	41%	0.413	S	S	*	.	H	α-helix	trans	-88.1	-34.5	-179.8	-70.5	-172.3	-153.4	-174.4	6.4	114	Y142 F143 Y144	Y142-R146 WeakPolarHBondContact O-CG 3.26Å; Y142-R146 PolarHBondContact O-N 3.32Å; F143-R146 PolarHBondContact O-N 3.02Å; Y144-R146 VanDerWaalsContact C-N 3.32Å; Y144-R146 PolarHBondContact O-N 3.47Å
147	R	71.4	Confident	75.1	Confident	186 Å²	186	81.3 Å²	81.3	70%	0.702	41%	0.409	S	S	*	.	H	α-helix	trans	-106.9	-28.8	-169.3	-67.4	-88.1	-81.4	-143.2	-2.4	113.1	F143 S149	F143-R147 HydrophobicContact CD1-CB 4.37Å; F143-R147 HydrophobicContact CD2-CG 3.92Å; F143-R147 HydrophobicContact CE1-CB 4.06Å; F143-R147 HydrophobicContact CE1-CG 4.31Å; F143-R147 HydrophobicContact CE2-CB 4.29Å; F143-R147 HydrophobicContact CE2-CG 3.64Å; F143-R147 HydrophobicContact CG-CG 4.39Å; F143-R147 HydrophobicContact CZ-CB 4.02Å; F143-R147 HydrophobicContact CZ-CG 3.85Å; F143-R147 WeakPolarHBondContact O-CB 3.44Å; F143-R147 PolarHBondContact O-N 2.94Å; R147-S149 PolarHBondContact O-N 2.88Å
148	V	68.3	Low	76.1	Confident	43 Å²	43	84.2 Å²	84.2	26%	0.261	43%	0.428	S	S	.	.			trans	-95.1	90.2	-179.2	-174.7	0	0	0	0	108.6	L66 L136 Y144	L66-V148 HydrophobicContact CD1-CG1 3.6Å; L136-V148 HydrophobicContact CD1-CG2 4.5Å; Y144-V148 HydrophobicContact CD2-CB 3.85Å; Y144-V148 HydrophobicContact CD2-CG1 4.21Å; Y144-V148 HydrophobicContact CD2-CG2 3.64Å; Y144-V148 HydrophobicContact CE2-CB 3.88Å; Y144-V148 HydrophobicContact CE2-CG1 3.71Å; Y144-V148 HydrophobicContact CE2-CG2 3.97Å; Y144-V148 HydrophobicContact CG-CB 4.3Å; Y144-V148 HydrophobicContact CG-CG2 4.33Å; Y144-V148 WeakPolarHBondContact O-CA 3.16Å; Y144-V148 VanDerWaalsContact O-CB 3.29Å; Y144-V148 WeakPolarHBondContact O-CB 3.4Å; Y144-V148 PolarHBondContact O-N 3.46Å
149	S	72.8	Confident	77.3	Confident	59 Å²	59	85.8 Å²	85.8	41%	0.413	44%	0.443	S	S	.	.			trans	-78.2	157.3	168.5	71.4	0	0	0	0	110.3	R147 S151 G152 G153	R147-S149 PolarHBondContact O-N 2.88Å; S149-S151 VanDerWaalsContact C-N 3.28Å; S149-S151 PolarHBondContact O-N 3.38Å; S149-S151 PolarHBondContact OG-OG 3.44Å; S149-S151 VanDerWaalsContact OG-OG 3.11Å; S149-G152 PolarHBondContact O-N 3.5Å; S149-G152 PolarHBondContact OG-N 2.93Å; S149-G152 VanDerWaalsContact OG-N 3.1Å; S149-G153 PolarHBondContact O-N 3.44Å
150	R	69.6	Low	78.6	Confident	144 Å²	144	85.5 Å²	85.5	54%	0.543	44%	0.438	S	S	.	.	H	α-helix	trans	-58.9	-38.8	175	-105.6	-178	170.4	146.7	-11.5	113.1	S63 L64 L154	S63-R150 VanDerWaalsContact CB-NH2 3.3Å; L64-R150 PolarHBondContact O-NH2 3.31Å; R150-L154 WeakPolarHBondContact O-CB 3.43Å; R150-L154 PolarHBondContact O-N 3.35Å
151	S	73.7	Confident	79.8	Confident	90 Å²	90	83.4 Å²	83.4	63%	0.629	43%	0.426	S	S	*	.	H	α-helix	trans	-67.8	-42.6	178.3	48.6	0	0	0	0	111.7	S149 L154 A155	S149-S151 VanDerWaalsContact C-N 3.28Å; S149-S151 PolarHBondContact O-N 3.38Å; S149-S151 PolarHBondContact OG-OG 3.44Å; S149-S151 VanDerWaalsContact OG-OG 3.11Å; S151-L154 PolarHBondContact O-N 3.49Å; S151-A155 WeakPolarHBondContact O-CB 3.39Å; S151-A155 PolarHBondContact O-N 3.03Å
152	G	77.6	Confident	80.9	Confident	39 Å²	39	82.9 Å²	82.9	40%	0.402	43%	0.427	S	S	.	.	H	α-helix	trans	-64.5	-40.9	175.9	0	0	0	0	0	112.5	S149 A155 V156	S149-G152 PolarHBondContact O-N 3.5Å; S149-G152 PolarHBondContact OG-N 2.93Å; S149-G152 VanDerWaalsContact OG-N 3.1Å; G152-A155 PolarHBondContact O-N 3.29Å; G152-V156 PolarHBondContact O-N 2.96Å
153	G	77.8	Confident	82	Confident	12 Å²	12	78.2 Å²	78.2	12%	0.124	42%	0.417	C	S	.	.	H	α-helix	trans	-65	-37.4	175.1	0	0	0	0	0	113.6	S149 V156	S149-G153 PolarHBondContact O-N 3.44Å; G153-V156 WeakPolarHBondContact O-CB 3.37Å; G153-V156 WeakPolarHBondContact O-CG2 3.1Å; G153-V156 PolarHBondContact O-N 3.13Å
154	L	83.1	Confident	82.9	Confident	95 Å²	95	73.6 Å²	73.6	50%	0.497	40%	0.397	S	S	.	.	H	α-helix	trans	-72.7	-31.2	176.2	-166.3	66.5	0	0	0	112.2	V69 R150 S151 V156 L157 P158	V69-L154 HydrophobicContact CG1-CD1 3.93Å; R150-L154 WeakPolarHBondContact O-CB 3.43Å; R150-L154 PolarHBondContact O-N 3.35Å; S151-L154 PolarHBondContact O-N 3.49Å; L154-V156 PolarHBondContact O-N 3.42Å; L154-L157 HydrophobicContact CD1-CD1 3.97Å; L154-L157 PolarHBondContact O-N 3.41Å; L154-P158 VanDerWaalsContact O-CD 3.28Å; L154-P158 WeakPolarHBondContact O-CD 3.47Å
155	A	87.3	Confident	83.9	Confident	54 Å²	54	75.6 Å²	75.6	45%	0.446	41%	0.41	S	S	.	.	H	α-helix	trans	-65.9	-15	174.8	0	0	0	0	0	113.6	S151 G152 L157 P158 A159	S151-A155 WeakPolarHBondContact O-CB 3.39Å; S151-A155 PolarHBondContact O-N 3.03Å; G152-A155 PolarHBondContact O-N 3.29Å; A155-L157 VanDerWaalsContact C-N 3.29Å; A155-L157 PolarHBondContact O-N 3.4Å; A155-P158 VanDerWaalsContact O-CD 3.31Å; A155-P158 WeakPolarHBondContact O-CD 3.29Å; A155-P158 WeakPolarHBondContact O-CG 3.09Å; A155-A159 WeakPolarHBondContact O-CB 3.35Å; A155-A159 PolarHBondContact O-N 3.26Å
156	V	89.8	Confident	84.9	Confident	54 Å²	54	73.5 Å²	73.5	33%	0.327	40%	0.404	S	S	.	.	H	α-helix	trans	-63.1	-36.2	173.4	178.3	0	0	0	0	111.3	A129 G152 G153 L154 A159 I160	A129-V156 HydrophobicContact CB-CG1 3.96Å; G152-V156 PolarHBondContact O-N 2.96Å; G153-V156 WeakPolarHBondContact O-CB 3.37Å; G153-V156 WeakPolarHBondContact O-CG2 3.1Å; G153-V156 PolarHBondContact O-N 3.13Å; L154-V156 PolarHBondContact O-N 3.42Å; V156-A159 PolarHBondContact O-N 3.34Å; V156-I160 HydrophobicContact CG1-CD1 3.67Å; V156-I160 HydrophobicContact CG1-CG1 4.09Å; V156-I160 VanDerWaalsContact O-CG1 3.27Å; V156-I160 WeakPolarHBondContact O-CG1 3.04Å; V156-I160 PolarHBondContact O-N 3.38Å
157	L	91.3	Very high	85.7	Confident	15 Å²	15	64.8 Å²	64.8	8%	0.079	37%	0.372	C	S	.	.	H	α-helix	trans	-60.3	-57.7	-179.3	-60.1	-176.9	0	0	0	113.2	V69 L70 E73 M126 L154 A155 A159 I160 Y161	V69-L157 HydrophobicContact CG1-CD1 4.02Å; L70-L157 HydrophobicContact CD2-CD2 3.69Å; E73-L157 HydrophobicContact CB-CD1 4.36Å; E73-L157 HydrophobicContact CB-CD2 4.05Å; E73-L157 HydrophobicContact CG-CD1 4.12Å; E73-L157 HydrophobicContact CG-CD2 3.9Å; M126-L157 HydrophobicContact CE-CD2 3.75Å; M126-L157 HydrophobicContact SD-CD2 3.6Å; L154-L157 HydrophobicContact CD1-CD1 3.97Å; L154-L157 PolarHBondContact O-N 3.41Å; A155-L157 VanDerWaalsContact C-N 3.29Å; A155-L157 PolarHBondContact O-N 3.4Å; L157-A159 PolarHBondContact O-N 2.83Å; L157-I160 PolarHBondContact O-N 3.2Å; L157-Y161 WeakPolarHBondContact O-CD2 3.17Å; L157-Y161 PolarHBondContact O-N 2.86Å; L157-Y161 VanDerWaalsContact O-N 3.16Å
158	P	93.5	Very high	86.5	Confident	81 Å²	81	56 Å²	56	53%	0.526	34%	0.338	S	S	.	.	H	α-helix	trans	-63.6	-30.8	177.9	25.8	-35	0	0	0	112.1	L154 A155 Y161 A162	L154-P158 VanDerWaalsContact O-CD 3.28Å; L154-P158 WeakPolarHBondContact O-CD 3.47Å; A155-P158 VanDerWaalsContact O-CD 3.31Å; A155-P158 WeakPolarHBondContact O-CD 3.29Å; A155-P158 WeakPolarHBondContact O-CG 3.09Å; P158-Y161 PolarHBondContact O-N 3.37Å; P158-A162 WeakPolarHBondContact O-CB 3.29Å; P158-A162 PolarHBondContact O-N 3.09Å
159	A	93.8	Very high	87.4	Confident	51 Å²	51	55.6 Å²	55.6	42%	0.421	34%	0.338	S	S	.	.	H	α-helix	trans	-64.7	-43.4	175.2	0	0	0	0	0	112.1	A155 V156 L157 A162 V163	A155-A159 WeakPolarHBondContact O-CB 3.35Å; A155-A159 PolarHBondContact O-N 3.26Å; V156-A159 PolarHBondContact O-N 3.34Å; L157-A159 PolarHBondContact O-N 2.83Å; A159-A162 PolarHBondContact O-N 3.26Å; A159-V163 WeakPolarHBondContact O-CB 3.14Å; A159-V163 VanDerWaalsContact O-CG2 3.29Å; A159-V163 WeakPolarHBondContact O-CG2 3.49Å; A159-V163 PolarHBondContact O-N 3.33Å
160	I	94.8	Very high	87.9	Confident	13 Å²	13	56.5 Å²	56.5	7%	0.067	34%	0.337	C	S	.	.	H	α-helix	trans	-58.3	-52.1	175.4	-72.3	169.6	0	0	0	110	A122 L125 M126 A129 V156 L157 A162 V163 S164	A122-I160 HydrophobicContact CB-CG2 4.44Å; L125-I160 HydrophobicContact CB-CB 4.39Å; L125-I160 HydrophobicContact CB-CD1 4.43Å; L125-I160 HydrophobicContact CB-CG1 4.06Å; L125-I160 HydrophobicContact CB-CG2 3.63Å; L125-I160 HydrophobicContact CD1-CG2 4.15Å; M126-I160 HydrophobicContact SD-CD1 3.98Å; A129-I160 HydrophobicContact CB-CD1 4Å; V156-I160 HydrophobicContact CG1-CD1 3.67Å; V156-I160 HydrophobicContact CG1-CG1 4.09Å; V156-I160 VanDerWaalsContact O-CG1 3.27Å; V156-I160 WeakPolarHBondContact O-CG1 3.04Å; V156-I160 PolarHBondContact O-N 3.38Å; L157-I160 PolarHBondContact O-N 3.2Å; I160-A162 VanDerWaalsContact C-N 3.34Å; I160-A162 PolarHBondContact O-N 2.99Å; I160-V163 PolarHBondContact O-N 2.67Å; I160-S164 WeakPolarHBondContact O-CB 3.16Å; I160-S164 PolarHBondContact O-N 2.97Å; I160-S164 PolarHBondContact O-OG 2.74Å
161	Y	94.9	Very high	88.4	Confident	51 Å²	51	49.8 Å²	49.8	20%	0.2	31%	0.313	C	S	.	.	H	α-helix	trans	-63.5	-39.2	-179.9	-67.5	-57.6	0	0	0	112.7	E73 T77 F118 A122 L157 P158 S164 L165	E73-Y161 HydrophobicContact CG-CE2 4.31Å; E73-Y161 VanDerWaalsContact CG-OH 3.29Å; E73-Y161 WeakPolarHBondContact CG-OH 3.18Å; E73-Y161 PolarHBondContact OE1-OH 3.48Å; T77-Y161 HydrophobicContact CG2-CE1 4.21Å; T77-Y161 PolarHBondContact OG1-OH 3.14Å; F118-Y161 HydrophobicContact CE1-CD1 4.45Å; F118-Y161 HydrophobicContact CE2-CD1 4.48Å; F118-Y161 AromaticContact CZ-CD1 3.74Å; F118-Y161 HydrophobicContact CZ-CD1 3.74Å; F118-Y161 HydrophobicContact CZ-CE1 4.47Å; A122-Y161 HydrophobicContact CB-CD1 4.23Å; A122-Y161 HydrophobicContact CB-CE1 4.17Å; L157-Y161 WeakPolarHBondContact O-CD2 3.17Å; L157-Y161 PolarHBondContact O-N 2.86Å; L157-Y161 VanDerWaalsContact O-N 3.16Å; P158-Y161 PolarHBondContact O-N 3.37Å; Y161-S164 PolarHBondContact O-N 3.3Å; Y161-L165 WeakPolarHBondContact O-CB 3.45Å; Y161-L165 PolarHBondContact O-N 3.29Å
162	A	95.1	Very high	88.7	Confident	57 Å²	57	49.3 Å²	49.3	47%	0.471	30%	0.303	S	S	.	.	H	α-helix	trans	-64.1	-44.4	177.4	0	0	0	0	0	111.9	P158 A159 I160 L165 L166	P158-A162 WeakPolarHBondContact O-CB 3.29Å; P158-A162 PolarHBondContact O-N 3.09Å; A159-A162 PolarHBondContact O-N 3.26Å; I160-A162 VanDerWaalsContact C-N 3.34Å; I160-A162 PolarHBondContact O-N 2.99Å; A162-L165 PolarHBondContact O-N 2.93Å; A162-L166 VanDerWaalsContact O-CB 3.3Å; A162-L166 WeakPolarHBondContact O-CB 3.3Å; A162-L166 PolarHBondContact O-N 2.86Å
163	V	94.2	Very high	88.5	Confident	78 Å²	78	53.8 Å²	53.8	47%	0.473	32%	0.317	S	S	.	.	H	α-helix	trans	-63.5	-45.5	176.1	170.4	0	0	0	0	110.7	L125 A159 I160 L165 L166 F167	L125-V163 HydrophobicContact CD1-CB 4.41Å; L125-V163 HydrophobicContact CD1-CG1 4.08Å; A159-V163 WeakPolarHBondContact O-CB 3.14Å; A159-V163 VanDerWaalsContact O-CG2 3.29Å; A159-V163 WeakPolarHBondContact O-CG2 3.49Å; A159-V163 PolarHBondContact O-N 3.33Å; I160-V163 PolarHBondContact O-N 2.67Å; V163-L165 PolarHBondContact O-N 3.27Å; V163-L166 PolarHBondContact O-N 3.5Å; V163-F167 WeakPolarHBondContact O-CB 3.42Å; V163-F167 PolarHBondContact O-N 3.16Å
164	S	94.4	Very high	88	Confident	0 Å²	0	58.4 Å²	58.4	0%	0	34%	0.338	C	S	.	.	H	α-helix	trans	-60.9	-45.2	176.4	-64.7	0	0	0	0	111.9	A122 I160 Y161 F167 C168	A122-S164 WeakPolarHBondContact CA-OG 3.28Å; A122-S164 PolarHBondContact N-OG 3.49Å; I160-S164 WeakPolarHBondContact O-CB 3.16Å; I160-S164 PolarHBondContact O-N 2.97Å; I160-S164 PolarHBondContact O-OG 2.74Å; Y161-S164 PolarHBondContact O-N 3.3Å; S164-F167 PolarHBondContact O-N 3.12Å; S164-C168 VanDerWaalsContact O-CB 3.26Å; S164-C168 WeakPolarHBondContact O-CB 3.31Å; S164-C168 PolarHBondContact O-N 3.37Å; S164-C168 PolarHBondContact O-SG 2.87Å
165	L	93.4	Very high	86.6	Confident	91 Å²	91	64.9 Å²	64.9	48%	0.476	36%	0.358	S	S	.	.	H	α-helix	trans	-62.8	-47.1	179.4	-178.9	61.3	0	0	0	111.4	F114 F118 Y161 A162 V163 F167 C168 S169	F114-L165 HydrophobicContact CZ-CD1 3.73Å; F118-L165 HydrophobicContact CE2-CB 4.14Å; Y161-L165 WeakPolarHBondContact O-CB 3.45Å; Y161-L165 PolarHBondContact O-N 3.29Å; A162-L165 PolarHBondContact O-N 2.93Å; V163-L165 PolarHBondContact O-N 3.27Å; L165-F167 PolarHBondContact O-N 3.42Å; L165-C168 PolarHBondContact O-N 2.97Å; L165-S169 VanDerWaalsContact O-CB 3.3Å; L165-S169 WeakPolarHBondContact O-CB 3.34Å; L165-S169 PolarHBondContact O-N 3.45Å; L165-S169 PolarHBondContact O-OG 3.2Å
166	L	91.9	Very high	85.1	Confident	118 Å²	118	64.7 Å²	64.7	62%	0.618	36%	0.361	S	S	*	.	H	α-helix	trans	-59.5	-49.1	177.9	-179.7	63	0	0	0	110.6	A162 V163 S169 L170	A162-L166 VanDerWaalsContact O-CB 3.3Å; A162-L166 WeakPolarHBondContact O-CB 3.3Å; A162-L166 PolarHBondContact O-N 2.86Å; V163-L166 PolarHBondContact O-N 3.5Å; L166-S169 PolarHBondContact O-N 3.33Å; L166-S169 PolarHBondContact O-OG 2.93Å; L166-L170 PolarHBondContact O-N 2.9Å
167	F	90.5	Very high	84.3	Confident	30 Å²	30	64.1 Å²	64.1	13%	0.132	36%	0.355	C	S	.	.	H	α-helix	trans	-61.5	-48.2	179.8	-171	-84.5	0	0	0	111.9	L121 V163 S164 L165 S169 L170 Y196 L199 Y200 L203	L121-F167 HydrophobicContact CD2-CB 3.78Å; L121-F167 HydrophobicContact CD2-CD1 3.72Å; L121-F167 HydrophobicContact CD2-CG 3.82Å; V163-F167 WeakPolarHBondContact O-CB 3.42Å; V163-F167 PolarHBondContact O-N 3.16Å; S164-F167 PolarHBondContact O-N 3.12Å; L165-F167 PolarHBondContact O-N 3.42Å; F167-S169 PolarHBondContact O-N 2.8Å; F167-L170 HydrophobicContact CD2-CD1 4.34Å; F167-L170 WeakPolarHBondContact O-CB 3.05Å; F167-L170 WeakPolarHBondContact O-CG 3.38Å; F167-L170 PolarHBondContact O-N 3.39Å; F167-Y196 HydrophobicContact CD1-CE2 4.04Å; F167-Y196 HydrophobicContact CE1-CD2 4.45Å; F167-Y196 AromaticContact CE1-CE2 3.49Å; F167-Y196 HydrophobicContact CE1-CE2 3.49Å; F167-Y196 VanDerWaalsContact CE1-CE2 3.49Å; F167-Y196 AromaticContact CE1-CZ 3.65Å; F167-Y196 WeakPolarHBondContact CE1-OH 3.23Å; F167-Y196 HydrophobicContact CZ-CD2 4.44Å; F167-Y196 AromaticContact CZ-CE2 3.85Å; F167-Y196 HydrophobicContact CZ-CE2 3.85Å; F167-Y196 PolarHBondContact O-OH 3.42Å; F167-L199 HydrophobicContact CZ-CB 4.35Å; F167-Y200 HydrophobicContact CD1-CD2 4.35Å; F167-Y200 AromaticContact CE1-CD2 3.58Å; F167-Y200 HydrophobicContact CE1-CD2 3.58Å; F167-Y200 HydrophobicContact CE1-CG 4.24Å; F167-Y200 HydrophobicContact CZ-CD2 4.25Å; F167-L203 HydrophobicContact CD2-CD2 4.04Å; F167-L203 HydrophobicContact CE2-CD2 3.95Å; F167-L203 HydrophobicContact CG-CD2 4.47Å; F167-L203 HydrophobicContact CZ-CD2 4.33Å
168	C	88.8	Confident	84	Confident	0 Å²	0	64.9 Å²	64.9	0%	0	36%	0.357	C	S	.	.	H	α-helix	trans	-69.1	-19.8	-179.4	-69.6	0	0	0	0	113.8	F114 T117 F118 S164 L165 P171	F114-C168 HydrophobicContact CD2-CB 3.93Å; F114-C168 WeakPolarHBondContact CD2-O 3.5Å; F114-C168 HydrophobicContact CE2-CB 3.63Å; F114-C168 HydrophobicContact CZ-CB 4.33Å; T117-C168 VanDerWaalsContact C-SG 3.51Å; T117-C168 PolarHBondContact OG1-SG 3.25Å; F118-C168 WeakPolarHBondContact CA-SG 3.43Å; F118-C168 HydrophobicContact CB-CB 4.36Å; F118-C168 PolarHBondContact N-SG 2.82Å; S164-C168 VanDerWaalsContact O-CB 3.26Å; S164-C168 WeakPolarHBondContact O-CB 3.31Å; S164-C168 PolarHBondContact O-N 3.37Å; S164-C168 PolarHBondContact O-SG 2.87Å; L165-C168 PolarHBondContact O-N 2.97Å; C168-P171 VanDerWaalsContact O-CD 3.28Å; C168-P171 WeakPolarHBondContact O-CD 3.05Å
169	S	87	Confident	83.5	Confident	36 Å²	36	61.4 Å²	61.4	25%	0.252	33%	0.334	S	S	.	.	H	α-helix	trans	-79.5	-18.6	175.6	71.6	0	0	0	0	113.7	L165 L166 F167 P171 L172	L165-S169 VanDerWaalsContact O-CB 3.3Å; L165-S169 WeakPolarHBondContact O-CB 3.34Å; L165-S169 PolarHBondContact O-N 3.45Å; L165-S169 PolarHBondContact O-OG 3.2Å; L166-S169 PolarHBondContact O-N 3.33Å; L166-S169 PolarHBondContact O-OG 2.93Å; F167-S169 PolarHBondContact O-N 2.8Å; S169-P171 VanDerWaalsContact C-CD 3.5Å; S169-L172 WeakPolarHBondContact O-CB 3.39Å; S169-L172 PolarHBondContact O-N 3.47Å
170	L	84.3	Confident	83	Confident	77 Å²	77	59.3 Å²	59.3	40%	0.403	32%	0.316	S	S	.	.	H	α-helix	trans	-54.6	-44.3	-179	-67.1	168.9	0	0	0	113.6	L166 F167 L172 L173 Y196	L166-L170 PolarHBondContact O-N 2.9Å; F167-L170 HydrophobicContact CD2-CD1 4.34Å; F167-L170 WeakPolarHBondContact O-CB 3.05Å; F167-L170 WeakPolarHBondContact O-CG 3.38Å; F167-L170 PolarHBondContact O-N 3.39Å; L170-L172 PolarHBondContact O-N 2.96Å; L170-L173 WeakPolarHBondContact O-CB 3.33Å; L170-L173 PolarHBondContact O-N 3.44Å; L170-Y196 HydrophobicContact CB-CD2 4.42Å; L170-Y196 HydrophobicContact CB-CE2 4.15Å; L170-Y196 HydrophobicContact CD1-CE2 4.46Å
171	P	80.4	Confident	82.4	Confident	4 Å²	4	59.4 Å²	59.4	3%	0.026	32%	0.315	C	S	.	.	H	α-helix	trans	-71.9	-12.6	178.6	-17.5	33.8	0	0	0	114.1	C168 S169 L173 D174 Q177 Y178 Y196	C168-P171 VanDerWaalsContact O-CD 3.28Å; C168-P171 WeakPolarHBondContact O-CD 3.05Å; S169-P171 VanDerWaalsContact C-CD 3.5Å; P171-L173 VanDerWaalsContact C-N 3.29Å; P171-D174 CarbonylContact O-C 3.6Å; P171-Q177 HydrophobicContact CB-CB 4.29Å; P171-Y178 HydrophobicContact CB-CE1 4.47Å; P171-Y178 HydrophobicContact CB-CE2 4.15Å; P171-Y196 HydrophobicContact CB-CD1 4.43Å; P171-Y196 HydrophobicContact CB-CE1 4.26Å; P171-Y196 HydrophobicContact CG-CD1 3.55Å; P171-Y196 HydrophobicContact CG-CD2 3.92Å; P171-Y196 HydrophobicContact CG-CE1 3.1Å; P171-Y196 HydrophobicContact CG-CE2 3.53Å; P171-Y196 HydrophobicContact CG-CG 3.93Å; P171-Y196 WeakPolarHBondContact CG-OH 3.47Å
172	L	78.1	Confident	81.6	Confident	79 Å²	79	58.7 Å²	58.7	41%	0.414	32%	0.318	S	S	.	.	H	α-helix	trans	-78	-20.2	175.7	-58.7	175.4	0	0	0	111.6	T110 F114 S169 L170 Y178	T110-L172 HydrophobicContact CG2-CD2 3.65Å; F114-L172 HydrophobicContact CD2-CD1 4.01Å; F114-L172 HydrophobicContact CE2-CD1 4.13Å; S169-L172 WeakPolarHBondContact O-CB 3.39Å; S169-L172 PolarHBondContact O-N 3.47Å; L170-L172 PolarHBondContact O-N 2.96Å; L172-Y178 HydrophobicContact CD2-CE2 4.12Å
173	L	74.8	Confident	80.5	Confident	133 Å²	133	56.7 Å²	56.7	70%	0.696	30%	0.3	S	S	*	.	H	α-helix	trans	-76.7	-30.6	175.9	-60.9	173	0	0	0	111.8	L170 P171	L170-L173 WeakPolarHBondContact O-CB 3.33Å; L170-L173 PolarHBondContact O-N 3.44Å; P171-L173 VanDerWaalsContact C-N 3.29Å
174	D	66.8	Low	79.9	Confident	109 Å²	109	53 Å²	53	58%	0.583	28%	0.277	S	S	*	.	S	Bend	trans	-104.9	92.7	173.5	-85.8	-31.2	0	0	0	109.9	P171 G176	P171-D174 CarbonylContact O-C 3.6Å; D174-G176 PolarHBondContact O-N 3.22Å
175	Y	54.4	Low	79.5	Confident	232 Å²	232	53 Å²	53	91%	0.91	28%	0.277	S	S	*	.	T	Hydrogen-bonded Turn	trans	-47.3	107.5	175.5	-71.1	-93	0	0	0	111.5
176	G	56	Low	79.1	Confident	50 Å²	50	49.2 Å²	49.2	52%	0.515	26%	0.257	S	S	.	.	T	Hydrogen-bonded Turn	trans	123.4	26.1	164.8	0	0	0	0	0	118.8	D174	D174-G176 PolarHBondContact O-N 3.22Å
177	Q	71.9	Confident	78.9	Confident	41 Å²	41	43.6 Å²	43.6	19%	0.192	23%	0.227	C	C	.	.			trans	-94.4	-8.7	177.6	-63.4	-162.3	8.8	0	0	116	P171 I189 R190 Y196	P171-Q177 HydrophobicContact CB-CB 4.29Å; Q177-I189 CarbonylContact O-C 3.55Å; Q177-R190 WeakPolarHBondContact O-CB 3.34Å; Q177-R190 PolarHBondContact O-N 2.81Å; Q177-Y196 VanDerWaalsContact OE1-CB 3.24Å
178	Y	85	Confident	78.7	Confident	31 Å²	31	42.3 Å²	42.3	12%	0.122	22%	0.222	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-97.9	128.5	179.1	-60.4	-57.9	0	0	0	111.2	T110 A113 P171 L172 F188 I189	T110-Y178 HydrophobicContact CG2-CD2 3.93Å; T110-Y178 HydrophobicContact CG2-CE2 4.05Å; A113-Y178 HydrophobicContact CB-CD1 3.31Å; A113-Y178 HydrophobicContact CB-CD2 4.31Å; A113-Y178 HydrophobicContact CB-CE1 3.64Å; A113-Y178 HydrophobicContact CB-CG 3.68Å; P171-Y178 HydrophobicContact CB-CE1 4.47Å; P171-Y178 HydrophobicContact CB-CE2 4.15Å; L172-Y178 HydrophobicContact CD2-CE2 4.12Å; Y178-F188 WeakPolarHBondContact CA-O 3.42Å; Y178-I189 HydrophobicContact CD1-CG1 4.21Å; Y178-I189 HydrophobicContact CE1-CG1 3.86Å
179	V	83.2	Confident	78.5	Confident	9 Å²	9	42.3 Å²	42.3	6%	0.055	22%	0.222	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-121.8	154.9	177.7	-61	0	0	0	0	110.7	Y181 C187 F188 R190	V179-Y181 HydrophobicContact CG2-CD2 4.28Å; V179-Y181 HydrophobicContact CG2-CE2 3.61Å; V179-C187 WeakPolarHBondContact O-CA 3.41Å; V179-F188 PolarHBondContact N-O 3.44Å; V179-F188 PolarHBondContact O-N 3.35Å; V179-F188 VanDerWaalsContact O-O 3.11Å; V179-R190 HydrophobicContact CG1-CB 3.84Å; V179-R190 HydrophobicContact CG1-CG 3.96Å; V179-R190 HydrophobicContact CG2-CB 4.15Å; V179-R190 HydrophobicContact CG2-CG 4.43Å
180	Q	84.1	Confident	78.2	Confident	6 Å²	6	45.7 Å²	45.7	3%	0.028	23%	0.229	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-84.7	133.3	174.3	178.7	175.1	-77.7	0	0	110.1	C13 R16 T98 V100	C13-Q180 PolarHBondContact O-NE2 2.97Å; R16-Q180 PolarHBondContact O-NE2 3.1Å; T98-Q180 PolarHBondContact OG1-OE1 2.89Å; V100-Q180 HydrophobicContact CG2-CB 4Å; V100-Q180 VanDerWaalsContact CG2-OE1 3.25Å
181	Y	81.9	Confident	77.6	Confident	15 Å²	15	43.3 Å²	43.3	6%	0.059	22%	0.216	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-102.9	140.1	174.9	-71.2	-95.2	0	0	0	110.6	V179 G184 W186 F188 I189 H191 D297 L301	V179-Y181 HydrophobicContact CG2-CD2 4.28Å; V179-Y181 HydrophobicContact CG2-CE2 3.61Å; Y181-G184 WeakPolarHBondContact O-CA 3.22Å; Y181-G184 PolarHBondContact O-N 3.47Å; Y181-W186 PolarHBondContact N-O 3.41Å; Y181-F188 HydrophobicContact CD2-CB 4.04Å; Y181-F188 HydrophobicContact CE2-CB 3.63Å; Y181-I189 PolarHBondContact OH-O 2.92Å; Y181-H191 HydrophobicContact CE1-CB 4.32Å; Y181-H191 WeakPolarHBondContact OH-CB 3.48Å; Y181-H191 PolarHBondContact OH-N 2.92Å; Y181-D297 HydrophobicContact CD1-CB 3.65Å; Y181-D297 HydrophobicContact CE1-CB 3.64Å; Y181-D297 WeakPolarHBondContact CE1-OD2 3.41Å; Y181-L301 HydrophobicContact CD2-CD1 4.13Å; Y181-L301 HydrophobicContact CE2-CD1 4.38Å; Y181-L301 HydrophobicContact CG-CD1 4.28Å
182	C	77.4	Confident	76.9	Confident	37 Å²	37	44.2 Å²	44.2	25%	0.25	23%	0.226	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.3	130.7	179.5	-108.2	0	0	0	0	112	C13	C13-C182 HydrophobicContact CB-CB 4.05Å; C13-C182 WeakPolarHBondContact CB-SG 3.43Å; C13-C182 WeakPolarHBondContact SG-CA 3.38Å; C13-C182 WeakPolarHBondContact SG-CB 3.5Å; C13-C182 PolarHBondContact SG-N 3.42Å; C13-C182 VanDerWaalsContact SG-N 3.42Å; C13-C182 CovalentContact SG-SG 2.02Å; C13-C182 PolarHBondContact SG-SG 3.02Å
183	P	73.1	Confident	76.1	Confident	14 Å²	14	50 Å²	50	9%	0.091	24%	0.242	C	C	.	.	T	Hydrogen-bonded Turn	cis	-90.3	11.6	20	35.5	-37.7	0	0	0	117.1	P20 E23	P20-P183 HydrophobicContact CG-CB 4.34Å; E23-P183 HydrophobicContact CG-CB 4.05Å
184	G	81.6	Confident	76.1	Confident	0 Å²	0	45.3 Å²	45.3	0%	0	22%	0.219	C	C	.	.	T	Hydrogen-bonded Turn	trans	104.2	5.9	177.4	0	0	0	0	0	115.4	T98 L99 Y181	T98-G184 WeakPolarHBondContact CA-O 3.34Å; T98-G184 WeakPolarHBondContact CB-O 3.46Å; L99-G184 PolarHBondContact N-O 3.28Å; Y181-G184 WeakPolarHBondContact O-CA 3.22Å; Y181-G184 PolarHBondContact O-N 3.47Å
185	T	84.7	Confident	76.8	Confident	0 Å²	0	43.5 Å²	43.5	0%	0	22%	0.219	C	C	.	.	T	Hydrogen-bonded Turn	trans	-99.1	1	178.8	50.8	0	0	0	0	113.3	L19 Y93 L99	L19-T185 HydrophobicContact CD1-CG2 4.36Å; L19-T185 HydrophobicContact CD2-CG2 3.63Å; L19-T185 HydrophobicContact CG-CG2 4.28Å; Y93-T185 HydrophobicContact CD2-CG2 4.18Å; Y93-T185 HydrophobicContact CE1-CG2 4.11Å; Y93-T185 HydrophobicContact CE2-CG2 3.7Å; Y93-T185 PolarHBondContact OH-OG1 3.3Å; L99-T185 VanDerWaalsContact CD1-O 3.25Å; L99-T185 WeakPolarHBondContact CD1-O 3.5Å
186	W	85.7	Confident	78.2	Confident	12 Å²	12	33 Å²	33	5%	0.045	18%	0.179	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-131.5	133.6	178.9	-68.7	71.8	0	0	0	109.9	F112 M116 Y181 L298 L301 R302 S305	F112-W186 HydrophobicContact CE1-CB 4.31Å; F112-W186 HydrophobicContact CE1-CD2 4.41Å; F112-W186 HydrophobicContact CE1-CE3 4.03Å; F112-W186 HydrophobicContact CZ-CD2 4.04Å; F112-W186 AromaticContact CZ-CE3 3.78Å; F112-W186 HydrophobicContact CZ-CE3 3.78Å; F112-W186 HydrophobicContact CZ-CG 4.46Å; F112-W186 HydrophobicContact CZ-CZ3 4.23Å; M116-W186 HydrophobicContact CE-CE3 3.68Å; M116-W186 HydrophobicContact CE-CZ3 3.97Å; Y181-W186 PolarHBondContact N-O 3.41Å; W186-L298 HydrophobicContact CB-CD1 3.88Å; W186-L298 HydrophobicContact CD2-CD1 4.39Å; W186-L298 HydrophobicContact CG-CD1 3.7Å; W186-L301 HydrophobicContact CE3-CB 4.36Å; W186-R302 HydrophobicContact CH2-CG 4.35Å; W186-R302 HydrophobicContact CZ2-CG 4.17Å; W186-S305 WeakPolarHBondContact CH2-OG 3.08Å
187	C	87.9	Confident	79.5	Confident	0 Å²	0	30.9 Å²	30.9	0%	0	16%	0.155	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-120.7	136.9	171.6	-77.8	0	0	0	0	110.3	L99 C109 F112 A113 V179	L99-C187 HydrophobicContact CD1-CB 4.03Å; C109-C187 WeakPolarHBondContact CA-SG 3.35Å; C109-C187 HydrophobicContact CB-CB 3.91Å; C109-C187 WeakPolarHBondContact CB-SG 3.21Å; C109-C187 WeakPolarHBondContact O-CB 3.32Å; C109-C187 WeakPolarHBondContact SG-CB 3.35Å; C109-C187 CovalentContact SG-SG 2.02Å; C109-C187 PolarHBondContact SG-SG 3Å; F112-C187 HydrophobicContact CD1-CB 3.94Å; F112-C187 VanDerWaalsContact CD1-N 3.35Å; F112-C187 VanDerWaalsContact CD1-O 3.23Å; F112-C187 WeakPolarHBondContact CD1-O 3.3Å; F112-C187 VanDerWaalsContact CE1-N 3.34Å; F112-C187 WeakPolarHBondContact CE1-O 3.36Å; A113-C187 HydrophobicContact CB-CB 4.32Å; V179-C187 WeakPolarHBondContact O-CA 3.41Å
188	F	86.1	Confident	80.1	Confident	3 Å²	3	32.5 Å²	32.5	1%	0.013	16%	0.163	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-152.4	175.2	178	-160.8	-105.8	0	0	0	111.3	M116 T117 Y178 V179 Y181 R190 L197 Y200 F280 L301	M116-F188 HydrophobicContact CE-CD2 3.75Å; M116-F188 HydrophobicContact CE-CE2 4.49Å; M116-F188 HydrophobicContact SD-CD2 3.39Å; M116-F188 WeakPolarHBondContact SD-CD2 3.45Å; M116-F188 HydrophobicContact SD-CE2 3.54Å; M116-F188 VanDerWaalsContact SD-CE2 3.54Å; M116-F188 HydrophobicContact SD-CG 4.47Å; T117-F188 HydrophobicContact CG2-CD2 4.22Å; T117-F188 HydrophobicContact CG2-CE2 3.41Å; T117-F188 VanDerWaalsContact CG2-CE2 3.41Å; T117-F188 HydrophobicContact CG2-CZ 3.82Å; Y178-F188 WeakPolarHBondContact CA-O 3.42Å; V179-F188 PolarHBondContact N-O 3.44Å; V179-F188 PolarHBondContact O-N 3.35Å; V179-F188 VanDerWaalsContact O-O 3.11Å; Y181-F188 HydrophobicContact CD2-CB 4.04Å; Y181-F188 HydrophobicContact CE2-CB 3.63Å; F188-R190 PolarHBondContact O-N 2.89Å; F188-L197 HydrophobicContact CE1-CD1 4.23Å; F188-Y200 HydrophobicContact CZ-CD1 4.33Å; F188-Y200 AromaticContact CZ-CE1 3.84Å; F188-Y200 HydrophobicContact CZ-CE1 3.84Å; F188-F280 HydrophobicContact CD1-CE2 4.39Å; F188-F280 AromaticContact CE1-CE2 3.63Å; F188-F280 HydrophobicContact CE1-CE2 3.63Å; F188-F280 AromaticContact CE1-CZ 3.54Å; F188-F280 HydrophobicContact CE1-CZ 3.54Å; F188-F280 AromaticContact CZ-CE2 3.97Å; F188-F280 HydrophobicContact CZ-CE2 3.97Å; F188-F280 AromaticContact CZ-CZ 3.75Å; F188-F280 HydrophobicContact CZ-CZ 3.75Å; F188-L301 HydrophobicContact CB-CD1 3.84Å; F188-L301 HydrophobicContact CB-CD2 3.98Å; F188-L301 HydrophobicContact CD1-CD2 3.56Å; F188-L301 HydrophobicContact CD2-CD2 3.72Å; F188-L301 HydrophobicContact CE1-CD2 3.92Å; F188-L301 HydrophobicContact CE2-CD2 4.04Å; F188-L301 HydrophobicContact CG-CD1 4.25Å; F188-L301 HydrophobicContact CG-CD2 3.44Å; F188-L301 VanDerWaalsContact CG-CD2 3.44Å; F188-L301 HydrophobicContact CZ-CD2 4.13Å
189	I	84.5	Confident	80.3	Confident	0 Å²	0	35.5 Å²	35.5	0%	0	18%	0.18	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-54.5	136.7	174.9	-54.2	160.3	0	0	0	109	T117 Q177 Y178 Y181 H191 Y196 L197 Y200	T117-I189 HydrophobicContact CG2-CD1 3.9Å; T117-I189 HydrophobicContact CG2-CG1 4.25Å; Q177-I189 CarbonylContact O-C 3.55Å; Y178-I189 HydrophobicContact CD1-CG1 4.21Å; Y178-I189 HydrophobicContact CE1-CG1 3.86Å; Y181-I189 PolarHBondContact OH-O 2.92Å; I189-H191 PolarHBondContact O-N 3.49Å; I189-Y196 HydrophobicContact CD1-CD1 3.74Å; I189-Y196 HydrophobicContact CD1-CE1 3.27Å; I189-Y196 HydrophobicContact CG1-CD1 4.02Å; I189-Y196 HydrophobicContact CG1-CE1 3.69Å; I189-Y196 HydrophobicContact CG2-CD1 3.84Å; I189-Y196 HydrophobicContact CG2-CE1 4.4Å; I189-L197 HydrophobicContact CB-CD1 4.22Å; I189-L197 HydrophobicContact CD1-CD1 4.37Å; I189-L197 HydrophobicContact CG2-CB 3.97Å; I189-L197 HydrophobicContact CG2-CD1 4.19Å; I189-Y200 HydrophobicContact CD1-CD1 4.24Å; I189-Y200 HydrophobicContact CD1-CG 4.42Å
190	R	80.6	Confident	80.5	Confident	107 Å²	107	35.1 Å²	35.1	40%	0.404	18%	0.178	S	C	.	.	P	Polyproline II helix	trans	-53.6	120.5	176.8	-176.2	176	-79.8	148	-1.7	110.7	Q177 V179 F188 G192	Q177-R190 WeakPolarHBondContact O-CB 3.34Å; Q177-R190 PolarHBondContact O-N 2.81Å; V179-R190 HydrophobicContact CG1-CB 3.84Å; V179-R190 HydrophobicContact CG1-CG 3.96Å; V179-R190 HydrophobicContact CG2-CB 4.15Å; V179-R190 HydrophobicContact CG2-CG 4.43Å; F188-R190 PolarHBondContact O-N 2.89Å; R190-G192 PolarHBondContact O-N 2.85Å
191	H	71.9	Confident	80.6	Confident	27 Å²	27	34.8 Å²	34.8	13%	0.125	18%	0.177	C	C	.	.	S	Bend	trans	-72.1	126.2	173.7	-177.4	85.1	0	0	0	110.4	Y181 I189 F283 K293	Y181-H191 HydrophobicContact CE1-CB 4.32Å; Y181-H191 WeakPolarHBondContact OH-CB 3.48Å; Y181-H191 PolarHBondContact OH-N 2.92Å; I189-H191 PolarHBondContact O-N 3.49Å; H191-F283 HydrophobicContact CB-CZ 4.28Å; H191-F283 AromaticContact CE1-CE1 3.7Å; H191-F283 AromaticContact CE1-CE2 3.51Å; H191-F283 AromaticContact CE1-CZ 3.2Å; H191-F283 WeakPolarHBondContact CE1-CZ 3.49Å; H191-F283 AromaticContact CG-CZ 3.51Å; H191-F283 AromaticContact ND1-CE1 3.16Å; H191-F283 WeakPolarHBondContact ND1-CE1 3.25Å; H191-F283 AromaticContact ND1-CE2 3.75Å; H191-F283 AromaticContact ND1-CZ 2.92Å; H191-F283 WeakPolarHBondContact ND1-CZ 3.31Å; H191-F283 AromaticContact NE2-CZ 3.95Å; H191-K293 WeakPolarHBondContact CD2-CE 3.44Å; H191-K293 PolarHBondContact CD2-NZ 3.36Å; H191-K293 WeakPolarHBondContact NE2-CE 3.14Å; H191-K293 PolarHBondContact NE2-NZ 3.45Å
192	G	65.8	Low	81	Confident	24 Å²	24	37 Å²	37	25%	0.247	19%	0.192	C	C	.	.	S	Bend	trans	155.5	171.2	-171.7	0	0	0	0	0	109	R190 T194	R190-G192 PolarHBondContact O-N 2.85Å; G192-T194 PolarHBondContact O-N 2.85Å
193	R	60.7	Low	81.6	Confident	199 Å²	199	37.6 Å²	37.6	75%	0.751	19%	0.192	S	C	*	.	S	Bend	trans	-71.3	51.6	174.8	-74	-178.4	166.3	163	-4.8	111.9
194	T	74.1	Confident	82.3	Confident	35 Å²	35	36.9 Å²	36.9	22%	0.215	19%	0.188	C	C	.	.			trans	-75.5	134.6	168.4	58.9	0	0	0	0	107.9	G192 Y196 L197 Q198	G192-T194 PolarHBondContact O-N 2.85Å; T194-Y196 PolarHBondContact O-N 3.41Å; T194-L197 PolarHBondContact O-N 3.07Å; T194-L197 WeakPolarHBondContact OG1-CB 3.35Å; T194-L197 PolarHBondContact OG1-N 3Å; T194-Q198 PolarHBondContact O-N 3.33Å
195	A	82.3	Confident	82.7	Confident	71 Å²	71	39.8 Å²	39.8	59%	0.587	20%	0.203	S	C	*	.	H	α-helix	trans	-56.1	-37.1	179.1	0	0	0	0	0	111	Q198 L199	A195-Q198 PolarHBondContact O-N 3.1Å; A195-L199 WeakPolarHBondContact O-CB 3.47Å; A195-L199 WeakPolarHBondContact O-CG 3.25Å; A195-L199 PolarHBondContact O-N 2.91Å
196	Y	84.3	Confident	83	Confident	13 Å²	13	45.2 Å²	45.2	5%	0.051	23%	0.231	C	C	.	.	H	α-helix	trans	-67.1	-45	179.8	-176.7	-108	0	0	0	113.9	F167 L170 P171 Q177 I189 T194 Q198 L199 Y200	F167-Y196 HydrophobicContact CD1-CE2 4.04Å; F167-Y196 HydrophobicContact CE1-CD2 4.45Å; F167-Y196 AromaticContact CE1-CE2 3.49Å; F167-Y196 HydrophobicContact CE1-CE2 3.49Å; F167-Y196 VanDerWaalsContact CE1-CE2 3.49Å; F167-Y196 AromaticContact CE1-CZ 3.65Å; F167-Y196 WeakPolarHBondContact CE1-OH 3.23Å; F167-Y196 HydrophobicContact CZ-CD2 4.44Å; F167-Y196 AromaticContact CZ-CE2 3.85Å; F167-Y196 HydrophobicContact CZ-CE2 3.85Å; F167-Y196 PolarHBondContact O-OH 3.42Å; L170-Y196 HydrophobicContact CB-CD2 4.42Å; L170-Y196 HydrophobicContact CB-CE2 4.15Å; L170-Y196 HydrophobicContact CD1-CE2 4.46Å; P171-Y196 HydrophobicContact CB-CD1 4.43Å; P171-Y196 HydrophobicContact CB-CE1 4.26Å; P171-Y196 HydrophobicContact CG-CD1 3.55Å; P171-Y196 HydrophobicContact CG-CD2 3.92Å; P171-Y196 HydrophobicContact CG-CE1 3.1Å; P171-Y196 HydrophobicContact CG-CE2 3.53Å; P171-Y196 HydrophobicContact CG-CG 3.93Å; P171-Y196 WeakPolarHBondContact CG-OH 3.47Å; Q177-Y196 VanDerWaalsContact OE1-CB 3.24Å; I189-Y196 HydrophobicContact CD1-CD1 3.74Å; I189-Y196 HydrophobicContact CD1-CE1 3.27Å; I189-Y196 HydrophobicContact CG1-CD1 4.02Å; I189-Y196 HydrophobicContact CG1-CE1 3.69Å; I189-Y196 HydrophobicContact CG2-CD1 3.84Å; I189-Y196 HydrophobicContact CG2-CE1 4.4Å; T194-Y196 PolarHBondContact O-N 3.41Å; Y196-Q198 VanDerWaalsContact C-N 3.28Å; Y196-Q198 PolarHBondContact O-N 3.34Å; Y196-L199 PolarHBondContact O-N 2.97Å; Y196-Y200 WeakPolarHBondContact O-CB 3.49Å; Y196-Y200 PolarHBondContact O-N 3.01Å
197	L	83.6	Confident	83.2	Confident	4 Å²	4	45 Å²	45	2%	0.021	23%	0.231	C	C	.	.	H	α-helix	trans	-62.6	-39.5	176.7	-177.8	66.6	0	0	0	111.1	F188 I189 T194 Y200 A201 F280 A284	F188-L197 HydrophobicContact CE1-CD1 4.23Å; I189-L197 HydrophobicContact CB-CD1 4.22Å; I189-L197 HydrophobicContact CD1-CD1 4.37Å; I189-L197 HydrophobicContact CG2-CB 3.97Å; I189-L197 HydrophobicContact CG2-CD1 4.19Å; T194-L197 PolarHBondContact O-N 3.07Å; T194-L197 WeakPolarHBondContact OG1-CB 3.35Å; T194-L197 PolarHBondContact OG1-N 3Å; L197-Y200 PolarHBondContact O-N 3.01Å; L197-A201 VanDerWaalsContact O-CB 3.29Å; L197-A201 WeakPolarHBondContact O-CB 3.49Å; L197-A201 PolarHBondContact O-N 3.43Å; L197-F280 HydrophobicContact CD1-CZ 4.33Å; L197-A284 HydrophobicContact CG-CB 4.46Å
198	Q	84.1	Confident	83.2	Confident	75 Å²	75	45.1 Å²	45.1	35%	0.35	23%	0.231	S	C	.	.	H	α-helix	trans	-66.6	-42.4	175.6	-68.5	-178	-33.1	0	0	111.9	T194 A195 Y196 Y200 A201 T202	T194-Q198 PolarHBondContact O-N 3.33Å; A195-Q198 PolarHBondContact O-N 3.1Å; Y196-Q198 VanDerWaalsContact C-N 3.28Å; Y196-Q198 PolarHBondContact O-N 3.34Å; Q198-Y200 VanDerWaalsContact C-N 3.34Å; Q198-Y200 PolarHBondContact O-N 2.9Å; Q198-A201 PolarHBondContact O-N 3.1Å; Q198-T202 WeakPolarHBondContact O-CB 3.39Å; Q198-T202 VanDerWaalsContact O-CG2 3.24Å; Q198-T202 WeakPolarHBondContact O-CG2 3.42Å; Q198-T202 PolarHBondContact O-N 2.9Å; Q198-T202 PolarHBondContact O-OG1 3.18Å
199	L	88.3	Confident	83.3	Confident	95 Å²	95	49 Å²	49	50%	0.497	26%	0.255	S	S	.	.	H	α-helix	trans	-61.1	-42.6	173.7	-75.1	171.8	0	0	0	111.6	F167 A195 Y196 T202 L203	F167-L199 HydrophobicContact CZ-CB 4.35Å; A195-L199 WeakPolarHBondContact O-CB 3.47Å; A195-L199 WeakPolarHBondContact O-CG 3.25Å; A195-L199 PolarHBondContact O-N 2.91Å; Y196-L199 PolarHBondContact O-N 2.97Å; L199-T202 VanDerWaalsContact CA-OG1 3.29Å; L199-T202 WeakPolarHBondContact CA-OG1 3.25Å; L199-T202 PolarHBondContact O-OG1 2.76Å; L199-L203 VanDerWaalsContact O-CB 3.28Å; L199-L203 WeakPolarHBondContact O-CB 3.34Å; L199-L203 PolarHBondContact O-N 2.93Å
200	Y	87.6	Confident	83.6	Confident	0 Å²	0	50.2 Å²	50.2	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-64.3	-49.5	176.3	-177.7	-114.6	0	0	0	111.2	S120 L121 F167 F188 I189 Y196 L197 Q198 T202 L203 L204 F280	S120-Y200 WeakPolarHBondContact CB-OH 3.3Å; S120-Y200 PolarHBondContact OG-OH 3.02Å; S120-Y200 VanDerWaalsContact OG-OH 3.13Å; L121-Y200 HydrophobicContact CB-CE2 4.39Å; F167-Y200 HydrophobicContact CD1-CD2 4.35Å; F167-Y200 AromaticContact CE1-CD2 3.58Å; F167-Y200 HydrophobicContact CE1-CD2 3.58Å; F167-Y200 HydrophobicContact CE1-CG 4.24Å; F167-Y200 HydrophobicContact CZ-CD2 4.25Å; F188-Y200 HydrophobicContact CZ-CD1 4.33Å; F188-Y200 AromaticContact CZ-CE1 3.84Å; F188-Y200 HydrophobicContact CZ-CE1 3.84Å; I189-Y200 HydrophobicContact CD1-CD1 4.24Å; I189-Y200 HydrophobicContact CD1-CG 4.42Å; Y196-Y200 WeakPolarHBondContact O-CB 3.49Å; Y196-Y200 PolarHBondContact O-N 3.01Å; L197-Y200 PolarHBondContact O-N 3.01Å; Q198-Y200 VanDerWaalsContact C-N 3.34Å; Q198-Y200 PolarHBondContact O-N 2.9Å; Y200-T202 PolarHBondContact O-N 2.93Å; Y200-L203 PolarHBondContact O-N 3.06Å; Y200-L204 HydrophobicContact CD1-CD1 4.1Å; Y200-L204 HydrophobicContact CD1-CG 4.47Å; Y200-L204 HydrophobicContact CD2-CG 4.48Å; Y200-L204 HydrophobicContact CE1-CD1 3.52Å; Y200-L204 HydrophobicContact CE1-CG 4.17Å; Y200-L204 HydrophobicContact CE2-CD1 4.34Å; Y200-L204 HydrophobicContact CE2-CD2 4.07Å; Y200-L204 HydrophobicContact CE2-CG 4.2Å; Y200-L204 WeakPolarHBondContact O-CG 3.15Å; Y200-L204 PolarHBondContact O-N 3.03Å; Y200-F280 AromaticContact CD1-CE1 3.75Å; Y200-F280 HydrophobicContact CD1-CE1 3.75Å; Y200-F280 AromaticContact CD1-CZ 3.92Å; Y200-F280 HydrophobicContact CD1-CZ 3.92Å; Y200-F280 AromaticContact CE1-CE1 3.54Å; Y200-F280 HydrophobicContact CE1-CE1 3.54Å; Y200-F280 AromaticContact CE1-CZ 3.73Å; Y200-F280 HydrophobicContact CE1-CZ 3.73Å
201	A	86.8	Confident	83.8	Confident	0 Å²	0	45.2 Å²	45.2	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-64.1	-38.9	179.6	0	0	0	0	0	113.3	L197 Q198 L205 A284 Y285	L197-A201 VanDerWaalsContact O-CB 3.29Å; L197-A201 WeakPolarHBondContact O-CB 3.49Å; L197-A201 PolarHBondContact O-N 3.43Å; Q198-A201 PolarHBondContact O-N 3.1Å; A201-L205 VanDerWaalsContact O-CB 3.29Å; A201-L205 WeakPolarHBondContact O-CB 3.14Å; A201-L205 PolarHBondContact O-N 2.74Å; A201-A284 HydrophobicContact CB-CB 3.4Å; A201-Y285 HydrophobicContact CB-CE2 4.2Å
202	T	89	Confident	84.4	Confident	62 Å²	62	47.6 Å²	47.6	38%	0.38	26%	0.26	S	S	.	.	H	α-helix	trans	-64.3	-43.5	174	48.6	0	0	0	0	111.3	Q198 L199 Y200 L205 L206 Y285	Q198-T202 WeakPolarHBondContact O-CB 3.39Å; Q198-T202 VanDerWaalsContact O-CG2 3.24Å; Q198-T202 WeakPolarHBondContact O-CG2 3.42Å; Q198-T202 PolarHBondContact O-N 2.9Å; Q198-T202 PolarHBondContact O-OG1 3.18Å; L199-T202 VanDerWaalsContact CA-OG1 3.29Å; L199-T202 WeakPolarHBondContact CA-OG1 3.25Å; L199-T202 PolarHBondContact O-OG1 2.76Å; Y200-T202 PolarHBondContact O-N 2.93Å; T202-L205 PolarHBondContact O-N 3.45Å; T202-L206 WeakPolarHBondContact O-CB 3.47Å; T202-L206 PolarHBondContact O-N 2.72Å; T202-Y285 WeakPolarHBondContact CA-OH 3.46Å; T202-Y285 HydrophobicContact CG2-CE1 4.35Å; T202-Y285 WeakPolarHBondContact CG2-OH 3.35Å; T202-Y285 PolarHBondContact N-OH 2.79Å
203	L	90.9	Very high	85.5	Confident	48 Å²	48	48.9 Å²	48.9	25%	0.251	27%	0.268	S	S	.	.	H	α-helix	trans	-61.5	-48	176.1	-179.7	60.8	0	0	0	111.5	L121 F167 L199 Y200 L205 L206 L207	L121-L203 HydrophobicContact CD1-CD2 3.67Å; L121-L203 HydrophobicContact CD1-CG 4.23Å; L121-L203 HydrophobicContact CD2-CD2 4.16Å; F167-L203 HydrophobicContact CD2-CD2 4.04Å; F167-L203 HydrophobicContact CE2-CD2 3.95Å; F167-L203 HydrophobicContact CG-CD2 4.47Å; F167-L203 HydrophobicContact CZ-CD2 4.33Å; L199-L203 VanDerWaalsContact O-CB 3.28Å; L199-L203 WeakPolarHBondContact O-CB 3.34Å; L199-L203 PolarHBondContact O-N 2.93Å; Y200-L203 PolarHBondContact O-N 3.06Å; L203-L205 PolarHBondContact O-N 2.79Å; L203-L206 PolarHBondContact O-N 2.83Å; L203-L207 HydrophobicContact CD1-CD1 4.45Å; L203-L207 HydrophobicContact CG-CD1 4.29Å; L203-L207 WeakPolarHBondContact O-CG 3.47Å; L203-L207 PolarHBondContact O-N 3.46Å
204	L	88.4	Confident	86.5	Confident	0 Å²	0	40.2 Å²	40.2	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-59.7	-45.7	176.1	-67.1	-169.7	0	0	0	111.6	L121 M124 Y200 L206 L207 I208 F280 T281	L121-L204 HydrophobicContact CD1-CD2 4.39Å; M124-L204 HydrophobicContact CB-CD2 4.47Å; M124-L204 HydrophobicContact CE-CD2 4.38Å; M124-L204 HydrophobicContact CG-CD2 3.91Å; M124-L204 HydrophobicContact SD-CD2 3.68Å; Y200-L204 HydrophobicContact CD1-CD1 4.1Å; Y200-L204 HydrophobicContact CD1-CG 4.47Å; Y200-L204 HydrophobicContact CD2-CG 4.48Å; Y200-L204 HydrophobicContact CE1-CD1 3.52Å; Y200-L204 HydrophobicContact CE1-CG 4.17Å; Y200-L204 HydrophobicContact CE2-CD1 4.34Å; Y200-L204 HydrophobicContact CE2-CD2 4.07Å; Y200-L204 HydrophobicContact CE2-CG 4.2Å; Y200-L204 WeakPolarHBondContact O-CG 3.15Å; Y200-L204 PolarHBondContact O-N 3.03Å; L204-L206 VanDerWaalsContact C-N 3.34Å; L204-L206 PolarHBondContact O-N 3.43Å; L204-L207 PolarHBondContact O-N 2.99Å; L204-I208 VanDerWaalsContact O-CG1 3.25Å; L204-I208 WeakPolarHBondContact O-CG1 3.19Å; L204-I208 PolarHBondContact O-N 3.44Å; L204-F280 HydrophobicContact CD1-CD1 3.73Å; L204-F280 HydrophobicContact CD1-CE1 3.71Å; L204-T281 HydrophobicContact CB-CG2 3.97Å
205	L	89.2	Confident	86.8	Confident	61 Å²	61	39.2 Å²	39.2	32%	0.319	23%	0.231	S	C	.	.	H	α-helix	trans	-60.9	-43.8	177.9	-179.5	63.1	0	0	0	111.7	A201 T202 L203 L207 I208 V209 T281 Y285	A201-L205 VanDerWaalsContact O-CB 3.29Å; A201-L205 WeakPolarHBondContact O-CB 3.14Å; A201-L205 PolarHBondContact O-N 2.74Å; T202-L205 PolarHBondContact O-N 3.45Å; L203-L205 PolarHBondContact O-N 2.79Å; L205-L207 VanDerWaalsContact C-N 3.34Å; L205-L207 PolarHBondContact O-N 3.29Å; L205-I208 PolarHBondContact O-N 3.16Å; L205-V209 HydrophobicContact CD1-CG2 4.4Å; L205-V209 WeakPolarHBondContact O-CG2 3.16Å; L205-V209 PolarHBondContact O-N 2.79Å; L205-T281 HydrophobicContact CB-CG2 4.46Å; L205-Y285 HydrophobicContact CD2-CE2 4.15Å
206	L	91.4	Very high	86.7	Confident	114 Å²	114	41.8 Å²	41.8	60%	0.597	23%	0.229	S	C	*	.	H	α-helix	trans	-62.7	-42.1	177.5	-176.4	142.1	0	0	0	111.3	T202 L203 L204 V209 A210	T202-L206 WeakPolarHBondContact O-CB 3.47Å; T202-L206 PolarHBondContact O-N 2.72Å; L203-L206 PolarHBondContact O-N 2.83Å; L204-L206 VanDerWaalsContact C-N 3.34Å; L204-L206 PolarHBondContact O-N 3.43Å; L206-V209 PolarHBondContact O-N 3.47Å; L206-A210 WeakPolarHBondContact O-CB 3.2Å; L206-A210 PolarHBondContact O-N 2.98Å
207	L	90.5	Very high	86.6	Confident	7 Å²	7	43 Å²	43	4%	0.037	24%	0.239	C	C	.	.	H	α-helix	trans	-62.4	-44.4	174.7	-71.2	170.7	0	0	0	111.5	L121 M124 L125 F128 L203 L204 L205 A210 V211	L121-L207 HydrophobicContact CD1-CD1 4.11Å; M124-L207 HydrophobicContact CB-CD1 3.92Å; L125-L207 HydrophobicContact CD2-CD1 4.04Å; L125-L207 HydrophobicContact CD2-CD2 3.78Å; L125-L207 HydrophobicContact CG-CD1 4.25Å; F128-L207 HydrophobicContact CB-CD2 4Å; F128-L207 HydrophobicContact CD1-CD2 4.27Å; F128-L207 HydrophobicContact CG-CD2 4.07Å; L203-L207 HydrophobicContact CD1-CD1 4.45Å; L203-L207 HydrophobicContact CG-CD1 4.29Å; L203-L207 WeakPolarHBondContact O-CG 3.47Å; L203-L207 PolarHBondContact O-N 3.46Å; L204-L207 PolarHBondContact O-N 2.99Å; L205-L207 VanDerWaalsContact C-N 3.34Å; L205-L207 PolarHBondContact O-N 3.29Å; L207-A210 PolarHBondContact O-N 3.41Å; L207-V211 WeakPolarHBondContact O-CB 3.33Å; L207-V211 WeakPolarHBondContact O-CG2 3.45Å; L207-V211 PolarHBondContact O-N 2.9Å
208	I	86.8	Confident	86.1	Confident	2 Å²	2	43 Å²	43	1%	0.01	24%	0.24	C	C	.	.	H	α-helix	trans	-58.4	-51.1	175.9	-67.3	162.4	0	0	0	110.9	L204 L205 A210 V211 L212 F273 L278 T281	L204-I208 VanDerWaalsContact O-CG1 3.25Å; L204-I208 WeakPolarHBondContact O-CG1 3.19Å; L204-I208 PolarHBondContact O-N 3.44Å; L205-I208 PolarHBondContact O-N 3.16Å; I208-A210 VanDerWaalsContact C-N 3.33Å; I208-A210 PolarHBondContact O-N 3.4Å; I208-V211 PolarHBondContact O-N 3.29Å; I208-L212 HydrophobicContact CG2-CD1 3.85Å; I208-L212 HydrophobicContact CG2-CG 4.45Å; I208-L212 WeakPolarHBondContact O-CB 3.25Å; I208-L212 VanDerWaalsContact O-CG 3.28Å; I208-L212 WeakPolarHBondContact O-CG 3.07Å; I208-L212 PolarHBondContact O-N 2.73Å; I208-F273 HydrophobicContact CB-CE1 4.3Å; I208-F273 HydrophobicContact CG1-CD1 4.29Å; I208-F273 HydrophobicContact CG1-CE1 3.58Å; I208-F273 HydrophobicContact CG1-CZ 4.1Å; I208-L278 HydrophobicContact CD1-CD2 4.39Å; I208-L278 HydrophobicContact CG2-CD2 4.24Å; I208-T281 HydrophobicContact CD1-CG2 3.96Å
209	V	89.1	Confident	85.6	Confident	86 Å²	86	43 Å²	43	52%	0.521	24%	0.241	S	C	.	.	H	α-helix	trans	-61.6	-43	179.2	172.4	0	0	0	0	111	L205 L206 L212 A213	L205-V209 HydrophobicContact CD1-CG2 4.4Å; L205-V209 WeakPolarHBondContact O-CG2 3.16Å; L205-V209 PolarHBondContact O-N 2.79Å; L206-V209 PolarHBondContact O-N 3.47Å; V209-L212 PolarHBondContact O-N 3.42Å; V209-A213 VanDerWaalsContact O-CB 3.31Å; V209-A213 WeakPolarHBondContact O-CB 3.2Å; V209-A213 PolarHBondContact O-N 3.16Å
210	A	90	Very high	85	Confident	25 Å²	25	41.3 Å²	41.3	21%	0.207	23%	0.232	C	C	.	.	H	α-helix	trans	-63.9	-44.2	179	0	0	0	0	0	112.1	F128 L206 L207 I208 A213 C214	F128-A210 HydrophobicContact CD2-CB 3.96Å; F128-A210 HydrophobicContact CE2-CB 3.72Å; L206-A210 WeakPolarHBondContact O-CB 3.2Å; L206-A210 PolarHBondContact O-N 2.98Å; L207-A210 PolarHBondContact O-N 3.41Å; I208-A210 VanDerWaalsContact C-N 3.33Å; I208-A210 PolarHBondContact O-N 3.4Å; A210-A213 PolarHBondContact O-N 3.42Å; A210-C214 WeakPolarHBondContact O-CB 3.13Å; A210-C214 PolarHBondContact O-N 2.9Å; A210-C214 PolarHBondContact O-SG 3.43Å
211	V	85.6	Confident	84.3	Confident	2 Å²	2	43 Å²	43	1%	0.012	24%	0.242	C	C	.	.	H	α-helix	trans	-60.4	-48.3	174.7	171.9	0	0	0	0	110.4	F128 A131 L207 I208 A213 C214 N215 T270 F273	F128-V211 HydrophobicContact CB-CG2 3.89Å; F128-V211 HydrophobicContact CD2-CG2 4.18Å; A131-V211 HydrophobicContact CB-CG1 4.17Å; L207-V211 WeakPolarHBondContact O-CB 3.33Å; L207-V211 WeakPolarHBondContact O-CG2 3.45Å; L207-V211 PolarHBondContact O-N 2.9Å; I208-V211 PolarHBondContact O-N 3.29Å; V211-A213 PolarHBondContact O-N 3.47Å; V211-C214 PolarHBondContact O-N 2.8Å; V211-N215 WeakPolarHBondContact CG1-ND2 3.3Å; V211-N215 WeakPolarHBondContact O-CB 2.92Å; V211-N215 PolarHBondContact O-N 2.87Å; V211-N215 PolarHBondContact O-ND2 3.4Å; V211-T270 HydrophobicContact CG1-CG2 3.66Å; V211-F273 HydrophobicContact CG2-CE1 4.37Å
212	L	84.9	Confident	83.4	Confident	77 Å²	77	44.7 Å²	44.7	40%	0.403	25%	0.25	S	S	.	.	H	α-helix	trans	-60.5	-44.8	178.7	-72.4	170.4	0	0	0	111.6	I208 V209 N215 F216 T270	I208-L212 HydrophobicContact CG2-CD1 3.85Å; I208-L212 HydrophobicContact CG2-CG 4.45Å; I208-L212 WeakPolarHBondContact O-CB 3.25Å; I208-L212 VanDerWaalsContact O-CG 3.28Å; I208-L212 WeakPolarHBondContact O-CG 3.07Å; I208-L212 PolarHBondContact O-N 2.73Å; V209-L212 PolarHBondContact O-N 3.42Å; L212-N215 PolarHBondContact O-N 3.37Å; L212-F216 VanDerWaalsContact O-CB 3.26Å; L212-F216 WeakPolarHBondContact O-CB 3.12Å; L212-F216 PolarHBondContact O-N 3.06Å; L212-T270 HydrophobicContact CD2-CG2 3.68Å; L212-T270 HydrophobicContact CG-CG2 4.43Å
213	A	87.1	Confident	82.6	Confident	50 Å²	50	45.9 Å²	45.9	41%	0.413	25%	0.254	S	S	.	.	H	α-helix	trans	-63.2	-41.7	177.7	0	0	0	0	0	112.4	V209 A210 V211 S217	V209-A213 VanDerWaalsContact O-CB 3.31Å; V209-A213 WeakPolarHBondContact O-CB 3.2Å; V209-A213 PolarHBondContact O-N 3.16Å; A210-A213 PolarHBondContact O-N 3.42Å; V211-A213 PolarHBondContact O-N 3.47Å; A213-S217 WeakPolarHBondContact O-CB 3.37Å; A213-S217 PolarHBondContact O-N 3.24Å; A213-S217 PolarHBondContact O-OG 3.47Å
214	C	83.5	Confident	81.9	Confident	17 Å²	17	50.5 Å²	50.5	12%	0.115	27%	0.268	C	S	.	.	H	α-helix	trans	-61.9	-50.9	175.9	-71.2	0	0	0	0	111	A131 A210 V211 F216 S217 V218	A131-C214 HydrophobicContact CB-CB 4.06Å; A210-C214 WeakPolarHBondContact O-CB 3.13Å; A210-C214 PolarHBondContact O-N 2.9Å; A210-C214 PolarHBondContact O-SG 3.43Å; V211-C214 PolarHBondContact O-N 2.8Å; C214-F216 PolarHBondContact O-N 3.41Å; C214-S217 WeakPolarHBondContact O-CB 3.33Å; C214-S217 PolarHBondContact O-N 2.81Å; C214-V218 WeakPolarHBondContact O-CG2 3.44Å; C214-V218 PolarHBondContact O-N 3.49Å
215	N	79.5	Confident	80.9	Confident	14 Å²	14	54.4 Å²	54.4	8%	0.075	29%	0.287	C	S	.	.	H	α-helix	trans	-63.3	-41.6	179.5	-77.7	-72.5	0	0	0	112.4	V211 L212 S217 V218 I219 T270	V211-N215 WeakPolarHBondContact CG1-ND2 3.3Å; V211-N215 WeakPolarHBondContact O-CB 2.92Å; V211-N215 PolarHBondContact O-N 2.87Å; V211-N215 PolarHBondContact O-ND2 3.4Å; L212-N215 PolarHBondContact O-N 3.37Å; N215-S217 VanDerWaalsContact C-N 3.34Å; N215-S217 PolarHBondContact O-N 3.04Å; N215-V218 WeakPolarHBondContact O-CB 3.24Å; N215-V218 PolarHBondContact O-N 3.03Å; N215-I219 WeakPolarHBondContact O-CG1 3.13Å; N215-I219 PolarHBondContact O-N 3.26Å; N215-T270 HydrophobicContact CB-CG2 4.48Å; N215-T270 VanDerWaalsContact CG-OG1 3.31Å; N215-T270 PolarHBondContact ND2-OG1 2.96Å
216	F	80.6	Confident	79.9	Confident	125 Å²	125	56 Å²	56	55%	0.548	29%	0.292	S	S	.	.	H	α-helix	trans	-61.4	-43.3	175.3	-178.4	-110	0	0	0	111.8	L212 C214 V218 I219 L220	L212-F216 VanDerWaalsContact O-CB 3.26Å; L212-F216 WeakPolarHBondContact O-CB 3.12Å; L212-F216 PolarHBondContact O-N 3.06Å; C214-F216 PolarHBondContact O-N 3.41Å; F216-V218 VanDerWaalsContact C-N 3.32Å; F216-V218 PolarHBondContact O-N 2.93Å; F216-I219 PolarHBondContact O-N 3.1Å; F216-L220 HydrophobicContact CD1-CD1 3.82Å; F216-L220 HydrophobicContact CD1-CG 4.3Å; F216-L220 HydrophobicContact CE1-CD1 3.33Å; F216-L220 HydrophobicContact CE1-CD2 4.5Å; F216-L220 HydrophobicContact CE1-CG 3.95Å; F216-L220 HydrophobicContact CE2-CD2 4.47Å; F216-L220 HydrophobicContact CE2-CG 4.36Å; F216-L220 HydrophobicContact CZ-CD1 3.76Å; F216-L220 HydrophobicContact CZ-CD2 4.09Å; F216-L220 HydrophobicContact CZ-CG 3.98Å; F216-L220 WeakPolarHBondContact O-CG 3.32Å; F216-L220 PolarHBondContact O-N 3.35Å
217	S	81	Confident	79.1	Confident	38 Å²	38	57.9 Å²	57.9	27%	0.266	29%	0.292	S	S	.	.	H	α-helix	trans	-62.6	-39.3	177.1	-60.9	0	0	0	0	112.3	A213 C214 N215 L220 N221	A213-S217 WeakPolarHBondContact O-CB 3.37Å; A213-S217 PolarHBondContact O-N 3.24Å; A213-S217 PolarHBondContact O-OG 3.47Å; C214-S217 WeakPolarHBondContact O-CB 3.33Å; C214-S217 PolarHBondContact O-N 2.81Å; N215-S217 VanDerWaalsContact C-N 3.34Å; N215-S217 PolarHBondContact O-N 3.04Å; S217-L220 PolarHBondContact O-N 3.32Å; S217-N221 WeakPolarHBondContact O-CB 3.31Å; S217-N221 PolarHBondContact O-N 3.07Å; S217-N221 PolarHBondContact O-ND2 2.9Å; S217-N221 VanDerWaalsContact O-ND2 3.16Å
218	V	74.3	Confident	78.3	Confident	5 Å²	5	65.7 Å²	65.7	3%	0.03	32%	0.32	C	S	.	.	H	α-helix	trans	-60.4	-49.1	173.2	167.5	0	0	0	0	111	Y135 I138 C214 N215 F216 L220 N221 L222 L263	Y135-V218 VanDerWaalsContact CA-CG2 3.43Å; Y135-V218 HydrophobicContact CD2-CG2 4.37Å; I138-V218 HydrophobicContact CD1-CG1 3.93Å; C214-V218 WeakPolarHBondContact O-CG2 3.44Å; C214-V218 PolarHBondContact O-N 3.49Å; N215-V218 WeakPolarHBondContact O-CB 3.24Å; N215-V218 PolarHBondContact O-N 3.03Å; F216-V218 VanDerWaalsContact C-N 3.32Å; F216-V218 PolarHBondContact O-N 2.93Å; V218-L220 VanDerWaalsContact C-N 3.35Å; V218-L220 PolarHBondContact O-N 2.73Å; V218-N221 PolarHBondContact O-N 3.04Å; V218-L222 HydrophobicContact CG1-CD1 3.94Å; V218-L222 VanDerWaalsContact O-CG 3.3Å; V218-L222 WeakPolarHBondContact O-CG 3.3Å; V218-L222 PolarHBondContact O-N 3.11Å; V218-L263 HydrophobicContact CG1-CD2 3.36Å
219	I	72.6	Confident	77.2	Confident	75 Å²	75	67.7 Å²	67.7	39%	0.385	34%	0.335	S	S	.	.	H	α-helix	trans	-58.9	-45.7	177.7	-67.1	165.3	0	0	0	110.8	N215 F216 N221 L222 I223	N215-I219 WeakPolarHBondContact O-CG1 3.13Å; N215-I219 PolarHBondContact O-N 3.26Å; F216-I219 PolarHBondContact O-N 3.1Å; I219-N221 PolarHBondContact O-N 2.97Å; I219-L222 PolarHBondContact O-N 2.92Å; I219-I223 HydrophobicContact CG2-CD1 3.81Å; I219-I223 HydrophobicContact CG2-CG1 4.44Å; I219-I223 VanDerWaalsContact O-CG1 3.31Å; I219-I223 WeakPolarHBondContact O-CG1 3.45Å; I219-I223 PolarHBondContact O-N 2.95Å
220	L	76.4	Confident	76	Confident	59 Å²	59	71.1 Å²	71.1	31%	0.309	34%	0.339	S	S	.	.	H	α-helix	trans	-61.3	-43.8	177.5	-74.3	-178	0	0	0	112.5	F216 S217 V218 L222 I223 R224	F216-L220 HydrophobicContact CD1-CD1 3.82Å; F216-L220 HydrophobicContact CD1-CG 4.3Å; F216-L220 HydrophobicContact CE1-CD1 3.33Å; F216-L220 HydrophobicContact CE1-CD2 4.5Å; F216-L220 HydrophobicContact CE1-CG 3.95Å; F216-L220 HydrophobicContact CE2-CD2 4.47Å; F216-L220 HydrophobicContact CE2-CG 4.36Å; F216-L220 HydrophobicContact CZ-CD1 3.76Å; F216-L220 HydrophobicContact CZ-CD2 4.09Å; F216-L220 HydrophobicContact CZ-CG 3.98Å; F216-L220 WeakPolarHBondContact O-CG 3.32Å; F216-L220 PolarHBondContact O-N 3.35Å; S217-L220 PolarHBondContact O-N 3.32Å; V218-L220 VanDerWaalsContact C-N 3.35Å; V218-L220 PolarHBondContact O-N 2.73Å; L220-L222 VanDerWaalsContact C-N 3.34Å; L220-I223 PolarHBondContact O-N 3Å; L220-R224 WeakPolarHBondContact O-CB 3.19Å; L220-R224 VanDerWaalsContact O-CG 3.29Å; L220-R224 WeakPolarHBondContact O-CG 3.22Å; L220-R224 PolarHBondContact O-N 3.27Å
221	N	72.2	Confident	74.6	Confident	37 Å²	37	78 Å²	78	20%	0.198	36%	0.359	C	S	.	.	H	α-helix	trans	-63.3	-41	177.4	-78.7	-37.4	0	0	0	111.6	S217 V218 I219 R224 M225	S217-N221 WeakPolarHBondContact O-CB 3.31Å; S217-N221 PolarHBondContact O-N 3.07Å; S217-N221 PolarHBondContact O-ND2 2.9Å; S217-N221 VanDerWaalsContact O-ND2 3.16Å; V218-N221 PolarHBondContact O-N 3.04Å; I219-N221 PolarHBondContact O-N 2.97Å; N221-R224 WeakPolarHBondContact O-CB 3.24Å; N221-R224 PolarHBondContact O-N 3.3Å; N221-M225 VanDerWaalsContact O-CG 3.3Å; N221-M225 WeakPolarHBondContact O-CG 3.47Å; N221-M225 PolarHBondContact O-N 2.86Å
222	L	69.3	Low	73.2	Confident	35 Å²	35	82.8 Å²	82.8	18%	0.183	39%	0.392	C	S	.	.	H	α-helix	trans	-63.4	-44.4	174.7	-70	165.1	0	0	0	112.4	I138 V218 I219 L220 R224 M225 H226 L263	I138-L222 HydrophobicContact CG2-CD2 4.16Å; I138-L222 HydrophobicContact CG2-CG 4.31Å; V218-L222 HydrophobicContact CG1-CD1 3.94Å; V218-L222 VanDerWaalsContact O-CG 3.3Å; V218-L222 WeakPolarHBondContact O-CG 3.3Å; V218-L222 PolarHBondContact O-N 3.11Å; I219-L222 PolarHBondContact O-N 2.92Å; L220-L222 VanDerWaalsContact C-N 3.34Å; L222-R224 VanDerWaalsContact C-N 3.3Å; L222-R224 PolarHBondContact O-N 3.39Å; L222-M225 PolarHBondContact O-N 2.98Å; L222-H226 WeakPolarHBondContact O-CB 3.44Å; L222-H226 PolarHBondContact O-N 3.25Å; L222-L263 HydrophobicContact CD1-CB 4.44Å; L222-L263 HydrophobicContact CD1-CD1 3.39Å; L222-L263 HydrophobicContact CD1-CD2 4.38Å; L222-L263 HydrophobicContact CD1-CG 4.26Å; L222-L263 HydrophobicContact CD2-CD1 3.84Å; L222-L263 HydrophobicContact CG-CD1 4.19Å
223	I	70.9	Confident	71.6	Confident	87 Å²	87	85.4 Å²	85.4	45%	0.446	40%	0.397	S	S	.	.	H	α-helix	trans	-60.8	-43.5	175.9	-68.8	167.8	0	0	0	109.9	I219 L220 H226 R227	I219-I223 HydrophobicContact CG2-CD1 3.81Å; I219-I223 HydrophobicContact CG2-CG1 4.44Å; I219-I223 VanDerWaalsContact O-CG1 3.31Å; I219-I223 WeakPolarHBondContact O-CG1 3.45Å; I219-I223 PolarHBondContact O-N 2.95Å; L220-I223 PolarHBondContact O-N 3Å; I223-H226 PolarHBondContact O-N 3.37Å; I223-R227 HydrophobicContact CG2-CG 4.31Å; I223-R227 WeakPolarHBondContact O-CB 3.2Å; I223-R227 VanDerWaalsContact O-CG 3.31Å; I223-R227 WeakPolarHBondContact O-CG 3.36Å; I223-R227 PolarHBondContact O-N 3.31Å
224	R	76.1	Confident	69.7	Low	145 Å²	145	88.4 Å²	88.4	55%	0.547	41%	0.414	S	S	.	.	H	α-helix	trans	-61.2	-44.7	175.9	-73.6	172.3	179.6	170.7	-0.8	111.6	L220 N221 L222 R227 R228	L220-R224 WeakPolarHBondContact O-CB 3.19Å; L220-R224 VanDerWaalsContact O-CG 3.29Å; L220-R224 WeakPolarHBondContact O-CG 3.22Å; L220-R224 PolarHBondContact O-N 3.27Å; N221-R224 WeakPolarHBondContact O-CB 3.24Å; N221-R224 PolarHBondContact O-N 3.3Å; L222-R224 VanDerWaalsContact C-N 3.3Å; L222-R224 PolarHBondContact O-N 3.39Å; R224-R227 PolarHBondContact O-N 3.46Å; R224-R228 WeakPolarHBondContact O-CB 3.43Å; R224-R228 WeakPolarHBondContact O-CG 3.26Å; R224-R228 PolarHBondContact O-N 3.01Å
225	M	68.6	Low	67.9	Low	81 Å²	81	89.8 Å²	89.8	40%	0.399	43%	0.431	S	S	.	.	H	α-helix	trans	-61.2	-43.9	174.6	-71.9	174.3	71.1	0	0	111.6	N221 L222 R228 S229 M256	N221-M225 VanDerWaalsContact O-CG 3.3Å; N221-M225 WeakPolarHBondContact O-CG 3.47Å; N221-M225 PolarHBondContact O-N 2.86Å; L222-M225 PolarHBondContact O-N 2.98Å; M225-R228 PolarHBondContact O-N 3.2Å; M225-S229 WeakPolarHBondContact O-CB 3Å; M225-S229 PolarHBondContact O-N 3.45Å; M225-M256 HydrophobicContact CE-CE 4.03Å; M225-M256 HydrophobicContact CE-SD 4.38Å
226	H	67.9	Low	66	Low	95 Å²	95	94.6 Å²	94.6	44%	0.44	46%	0.463	S	S	.	.	H	α-helix	trans	-66.4	-41.8	179.4	-166.6	45.6	0	0	0	112	L222 I223 S229 R230	L222-H226 WeakPolarHBondContact O-CB 3.44Å; L222-H226 PolarHBondContact O-N 3.25Å; I223-H226 PolarHBondContact O-N 3.37Å; H226-S229 PolarHBondContact O-N 3.45Å; H226-R230 PolarHBondContact NE2-NE 2.96Å; H226-R230 VanDerWaalsContact NE2-NE 3.1Å; H226-R230 WeakPolarHBondContact O-CG 3.45Å; H226-R230 PolarHBondContact O-N 2.92Å
227	R	74.2	Confident	64.2	Low	154 Å²	154	94.5 Å²	94.5	58%	0.581	48%	0.478	S	S	*	.	H	α-helix	trans	-64.2	-41.9	174.8	-70.5	-177.6	86.5	-179.6	7.1	111.9	I223 R224 R230 R231	I223-R227 HydrophobicContact CG2-CG 4.31Å; I223-R227 WeakPolarHBondContact O-CB 3.2Å; I223-R227 VanDerWaalsContact O-CG 3.31Å; I223-R227 WeakPolarHBondContact O-CG 3.36Å; I223-R227 PolarHBondContact O-N 3.31Å; R224-R227 PolarHBondContact O-N 3.46Å; R227-R230 PolarHBondContact O-N 2.89Å; R227-R231 WeakPolarHBondContact O-CG 3.23Å; R227-R231 PolarHBondContact O-N 3.27Å
228	R	73.8	Confident	62.4	Low	170 Å²	170	100.2 Å²	100.2	64%	0.642	51%	0.505	S	S	*	.	H	α-helix	trans	-61.7	-48.2	173.6	-75.3	177.4	-177.9	171.1	1.3	111.2	R224 M225 R230 R231 S232	R224-R228 WeakPolarHBondContact O-CB 3.43Å; R224-R228 WeakPolarHBondContact O-CG 3.26Å; R224-R228 PolarHBondContact O-N 3.01Å; M225-R228 PolarHBondContact O-N 3.2Å; R228-R230 VanDerWaalsContact C-N 3.31Å; R228-R230 PolarHBondContact O-N 2.86Å; R228-R231 PolarHBondContact O-N 3.49Å; R228-R231 VanDerWaalsContact O-N 3.13Å; R228-S232 PolarHBondContact O-N 2.9Å; R228-S232 PolarHBondContact O-OG 3.47Å; R228-S232 VanDerWaalsContact O-OG 3.06Å
229	S	63.5	Low	60.7	Low	45 Å²	45	103.6 Å²	103.6	32%	0.315	54%	0.54	S	S	.	.	H	α-helix	trans	-65.2	-30	179.5	-167.6	0	0	0	0	113.5	M225 H226 R233	M225-S229 WeakPolarHBondContact O-CB 3Å; M225-S229 PolarHBondContact O-N 3.45Å; H226-S229 PolarHBondContact O-N 3.45Å; S229-R233 VanDerWaalsContact O-CG 3.32Å; S229-R233 WeakPolarHBondContact O-CG 3.21Å; S229-R233 PolarHBondContact O-N 3.28Å; S229-R233 PolarHBondContact O-NE 3.45Å; S229-R233 PolarHBondContact OG-NH2 3.26Å
230	R	63.4	Low	59	Low	158 Å²	158	106.4 Å²	106.4	60%	0.596	57%	0.567	S	S	*	*	H	α-helix	trans	-71.6	-42.1	170	-78.2	-168.2	-179.1	-133	3.6	112.1	H226 R227 R228 S232 R233 C234	H226-R230 PolarHBondContact NE2-NE 2.96Å; H226-R230 VanDerWaalsContact NE2-NE 3.1Å; H226-R230 WeakPolarHBondContact O-CG 3.45Å; H226-R230 PolarHBondContact O-N 2.92Å; R227-R230 PolarHBondContact O-N 2.89Å; R228-R230 VanDerWaalsContact C-N 3.31Å; R228-R230 PolarHBondContact O-N 2.86Å; R230-S232 VanDerWaalsContact C-N 3.34Å; R230-S232 PolarHBondContact O-N 3.48Å; R230-R233 PolarHBondContact O-N 3.32Å; R230-C234 PolarHBondContact O-N 2.9Å; R230-C234 VanDerWaalsContact O-N 3.16Å
231	R	60.8	Low	56.9	Low	169 Å²	169	106.9 Å²	106.9	64%	0.638	59%	0.585	S	S	*	*	H	α-helix	trans	-61.5	-40.7	174.5	-74.8	174.9	-177.4	158.7	-1.8	112.1	R227 R228 R233 C234 G235	R227-R231 WeakPolarHBondContact O-CG 3.23Å; R227-R231 PolarHBondContact O-N 3.27Å; R228-R231 PolarHBondContact O-N 3.49Å; R228-R231 VanDerWaalsContact O-N 3.13Å; R231-R233 PolarHBondContact O-N 3.47Å; R231-C234 PolarHBondContact O-N 2.89Å; R231-G235 PolarHBondContact O-N 2.79Å
232	S	57.2	Low	55.4	Low	102 Å²	102	117.8 Å²	117.8	71%	0.713	62%	0.624	S	S	*	*	T	Hydrogen-bonded Turn	trans	-68.3	-18.4	174	-52.4	0	0	0	0	113.9	R228 R230	R228-S232 PolarHBondContact O-N 2.9Å; R228-S232 PolarHBondContact O-OG 3.47Å; R228-S232 VanDerWaalsContact O-OG 3.06Å; R230-S232 VanDerWaalsContact C-N 3.34Å; R230-S232 PolarHBondContact O-N 3.48Å
233	R	51.6	Low	53.8	Low	132 Å²	132	119 Å²	119	50%	0.498	65%	0.645	S	S	.	*	T	Hydrogen-bonded Turn	trans	-88.5	-18.9	175	-80.9	178.5	-120.5	-152.2	-4.5	113.8	S229 R230 R231	S229-R233 VanDerWaalsContact O-CG 3.32Å; S229-R233 WeakPolarHBondContact O-CG 3.21Å; S229-R233 PolarHBondContact O-N 3.28Å; S229-R233 PolarHBondContact O-NE 3.45Å; S229-R233 PolarHBondContact OG-NH2 3.26Å; R230-R233 PolarHBondContact O-N 3.32Å; R231-R233 PolarHBondContact O-N 3.47Å
234	C	45.9	Very low	52.2	Low	114 Å²	114	117.9 Å²	117.9	77%	0.77	65%	0.654	S	S	*	*	S	Bend	trans	-106.2	15.6	178.7	-71	0	0	0	0	113.1	R230 R231	R230-C234 PolarHBondContact O-N 2.9Å; R230-C234 VanDerWaalsContact O-N 3.16Å; R231-C234 PolarHBondContact O-N 2.89Å
235	G	45.4	Very low	50.8	Low	45 Å²	45	115 Å²	115	46%	0.464	66%	0.655	S	S	.	*	S	Bend	trans	-72.7	136.8	168	0	0	0	0	0	110	R231 S237	R231-G235 PolarHBondContact O-N 2.79Å; G235-S237 PolarHBondContact O-N 2.96Å; G235-S237 VanDerWaalsContact O-N 3.16Å
236	P	40.3	Very low	49.5	Very low	116 Å²	116	113.5 Å²	113.5	75%	0.753	66%	0.66	S	S	*	*			trans	-60.4	121.2	178.2	23.6	-30.1	0	0	0	109.2	L238	P236-L238 HydrophobicContact CB-CD1 4.31Å; P236-L238 PolarHBondContact O-N 3.48Å
237	S	41.9	Very low	48.1	Very low	123 Å²	123	113 Å²	113	86%	0.86	67%	0.672	S	S	*	*			trans	-67.7	94.8	176	47.5	0	0	0	0	109.8	G235	G235-S237 PolarHBondContact O-N 2.96Å; G235-S237 VanDerWaalsContact O-N 3.16Å
238	L	43.4	Very low	46.4	Very low	158 Å²	158	115.9 Å²	115.9	83%	0.827	68%	0.683	S	S	*	*			trans	-107.1	117	158.1	-83.7	94.2	0	0	0	109.1	P236	P236-L238 HydrophobicContact CB-CD1 4.31Å; P236-L238 PolarHBondContact O-N 3.48Å
239	G	39.6	Very low	45	Very low	75 Å²	75	114.4 Å²	114.4	77%	0.773	68%	0.677	S	S	*	*	S	Bend	trans	96.7	96.3	151.2	0	0	0	0	0	118.2
240	S	37.1	Very low	43.6	Very low	135 Å²	135	121.4 Å²	121.4	94%	0.944	70%	0.697	S	S	*	*			trans	51.4	125.3	133.8	-156.6	0	0	0	0	121.6
241	G	32.5	Very low	42.2	Very low	68 Å²	68	116 Å²	116	70%	0.701	69%	0.69	S	S	*	*			trans	167.8	85.9	164.1	0	0	0	0	0	113.3	G243	G241-G243 PolarHBondContact O-N 3.39Å
242	R	39.6	Very low	41.2	Very low	266 Å²	266	114.2 Å²	114.2	100%	1.004	69%	0.689	S	S	*	*			trans	-64.3	81.9	-177.2	-164.2	172.7	168	-170.1	-4.1	111.7
243	G	36.6	Very low	40.2	Very low	61 Å²	61	116.2 Å²	116.2	63%	0.629	68%	0.681	S	S	*	*	S	Bend	trans	-163.8	105.1	171.7	0	0	0	0	0	109.8	G241	G241-G243 PolarHBondContact O-N 3.39Å
244	G	37.2	Very low	39.6	Very low	63 Å²	63	113.8 Å²	113.8	65%	0.649	68%	0.681	S	S	*	*			trans	-43.4	119.4	-160.3	0	0	0	0	0	116.5	G246	G244-G246 PolarHBondContact O-N 2.89Å
245	P	46.4	Very low	39.4	Very low	86 Å²	86	111.8 Å²	111.8	56%	0.558	67%	0.668	S	S	*	*	H	α-helix	trans	-69.2	-12.5	173.7	-0	8.2	0	0	0	113.2	R249	P245-R249 WeakPolarHBondContact O-CB 3.38Å; P245-R249 WeakPolarHBondContact O-CG 3.32Å; P245-R249 PolarHBondContact O-N 2.02Å
246	G	42	Very low	39.3	Very low	49 Å²	49	113 Å²	113	51%	0.505	66%	0.662	S	S	.	*	H	α-helix	trans	-67.3	-41	-172.1	0	0	0	0	0	114.5	G244 R250	G244-G246 PolarHBondContact O-N 2.89Å; G246-R250 WeakPolarHBondContact O-CB 3.21Å; G246-R250 PolarHBondContact O-N 3.27Å
247	A	37.7	Very low	39.5	Very low	83 Å²	83	109.3 Å²	109.3	69%	0.686	64%	0.642	S	S	*	*	H	α-helix	trans	-76	-43.3	-177	0	0	0	0	0	112.3	R250 G251	A247-R250 PolarHBondContact O-N 2.79Å; A247-G251 PolarHBondContact O-N 2.97Å
248	R	39.2	Very low	39.8	Very low	216 Å²	216	108.5 Å²	108.5	82%	0.815	63%	0.625	S	S	*	*	H	α-helix	trans	-65.1	-44.8	173.9	-123.7	178.6	-177.5	-175.2	0.4	111.5	R250 G251 E252	R248-R250 VanDerWaalsContact C-N 3.26Å; R248-R250 PolarHBondContact O-N 3.32Å; R248-G251 PolarHBondContact O-N 3.15Å; R248-E252 VanDerWaalsContact O-CB 3.25Å; R248-E252 WeakPolarHBondContact O-CB 3.38Å; R248-E252 PolarHBondContact O-N 3.39Å
249	R	43	Very low	40.1	Very low	139 Å²	139	104.3 Å²	104.3	53%	0.525	60%	0.601	S	S	.	*	H	α-helix	trans	-63.9	-24.6	174.4	-79.5	179.1	175.7	-172.9	-1.1	114.1	P245 R253	P245-R249 WeakPolarHBondContact O-CB 3.38Å; P245-R249 WeakPolarHBondContact O-CG 3.32Å; P245-R249 PolarHBondContact O-N 2.02Å; R249-R253 VanDerWaalsContact O-CB 3.25Å; R249-R253 WeakPolarHBondContact O-CB 2.94Å; R249-R253 WeakPolarHBondContact O-CG 3.32Å; R249-R253 PolarHBondContact O-N 3.4Å; R249-R253 PolarHBondContact O-NE 2.81Å
250	R	34.6	Very low	40.7	Very low	191 Å²	191	102.9 Å²	102.9	72%	0.721	58%	0.577	S	S	*	*	H	α-helix	trans	-87.3	-41.6	178.5	-163.1	169.1	-172.2	178.5	1.2	110.6	G246 A247 R248 R253 V254	G246-R250 WeakPolarHBondContact O-CB 3.21Å; G246-R250 PolarHBondContact O-N 3.27Å; A247-R250 PolarHBondContact O-N 2.79Å; R248-R250 VanDerWaalsContact C-N 3.26Å; R248-R250 PolarHBondContact O-N 3.32Å; R250-R253 PolarHBondContact O-N 2.86Å; R250-V254 WeakPolarHBondContact O-CB 2.94Å; R250-V254 WeakPolarHBondContact O-CG2 3.23Å; R250-V254 PolarHBondContact O-N 2.85Å
251	G	34.3	Very low	41.4	Very low	44 Å²	44	96.6 Å²	96.6	45%	0.454	53%	0.533	S	S	.	.	H	α-helix	trans	-62.4	-42.4	172.8	0	0	0	0	0	113.4	A247 R248 V254 S255	A247-G251 PolarHBondContact O-N 2.97Å; R248-G251 PolarHBondContact O-N 3.15Å; G251-V254 PolarHBondContact O-N 2.93Å; G251-S255 VanDerWaalsContact O-CB 3.32Å; G251-S255 WeakPolarHBondContact O-CB 3.43Å; G251-S255 PolarHBondContact O-N 3.44Å
252	E	39.3	Very low	42.6	Very low	133 Å²	133	94.2 Å²	94.2	62%	0.621	50%	0.504	S	S	*	.	H	α-helix	trans	-72.1	-34.1	178.7	-156.1	178.1	167.8	0	0	112.1	R248 M256	R248-E252 VanDerWaalsContact O-CB 3.25Å; R248-E252 WeakPolarHBondContact O-CB 3.38Å; R248-E252 PolarHBondContact O-N 3.39Å; E252-M256 VanDerWaalsContact O-CB 3.26Å; E252-M256 WeakPolarHBondContact O-CB 3.46Å; E252-M256 WeakPolarHBondContact O-CG 3.2Å; E252-M256 PolarHBondContact O-N 2.7Å
253	R	37.3	Very low	43.5	Very low	143 Å²	143	82.3 Å²	82.3	54%	0.54	46%	0.46	S	S	.	.	H	α-helix	trans	-71.2	-35	172.2	-81.5	-171.8	-91.4	-169.9	-2.9	113.2	R249 R250 A257	R249-R253 VanDerWaalsContact O-CB 3.25Å; R249-R253 WeakPolarHBondContact O-CB 2.94Å; R249-R253 WeakPolarHBondContact O-CG 3.32Å; R249-R253 PolarHBondContact O-N 3.4Å; R249-R253 PolarHBondContact O-NE 2.81Å; R250-R253 PolarHBondContact O-N 2.86Å; R253-A257 WeakPolarHBondContact O-CB 3.23Å; R253-A257 PolarHBondContact O-N 3.4Å
254	V	39.3	Very low	44.7	Very low	81 Å²	81	81.2 Å²	81.2	49%	0.491	44%	0.439	S	S	.	.	H	α-helix	trans	-74.2	-42.1	177.8	171.1	0	0	0	0	110.7	R250 G251 A257 E258	R250-V254 WeakPolarHBondContact O-CB 2.94Å; R250-V254 WeakPolarHBondContact O-CG2 3.23Å; R250-V254 PolarHBondContact O-N 2.85Å; G251-V254 PolarHBondContact O-N 2.93Å; V254-A257 PolarHBondContact O-N 3.3Å; V254-E258 PolarHBondContact O-N 3.09Å; V254-E258 VanDerWaalsContact O-N 3.1Å
255	S	40.5	Very low	45.9	Very low	73 Å²	73	78.3 Å²	78.3	51%	0.51	41%	0.409	S	S	.	.	H	α-helix	trans	-63.4	-42.5	174.4	-168.1	0	0	0	0	112.2	G251 E259	G251-S255 VanDerWaalsContact O-CB 3.32Å; G251-S255 WeakPolarHBondContact O-CB 3.43Å; G251-S255 PolarHBondContact O-N 3.44Å; S255-E259 PolarHBondContact O-N 3.33Å
256	M	44.3	Very low	46.7	Very low	69 Å²	69	74.5 Å²	74.5	34%	0.34	38%	0.384	S	S	.	.	H	α-helix	trans	-69.8	-32.4	176.3	-73	-67.3	-56.5	0	0	112.7	M225 E252 E259 T260	M225-M256 HydrophobicContact CE-CE 4.03Å; M225-M256 HydrophobicContact CE-SD 4.38Å; E252-M256 VanDerWaalsContact O-CB 3.26Å; E252-M256 WeakPolarHBondContact O-CB 3.46Å; E252-M256 WeakPolarHBondContact O-CG 3.2Å; E252-M256 PolarHBondContact O-N 2.7Å; M256-E259 PolarHBondContact O-N 3.43Å; M256-T260 VanDerWaalsContact O-CG2 3.24Å; M256-T260 WeakPolarHBondContact O-CG2 3.46Å; M256-T260 PolarHBondContact O-N 3.05Å; M256-T260 PolarHBondContact O-OG1 3.45Å
257	A	43.9	Very low	47.8	Very low	40 Å²	40	73.6 Å²	73.6	33%	0.331	37%	0.371	S	S	.	.	H	α-helix	trans	-69.9	-43.1	178.7	0	0	0	0	0	112.1	R253 V254 E259 T260 D261	R253-A257 WeakPolarHBondContact O-CB 3.23Å; R253-A257 PolarHBondContact O-N 3.4Å; V254-A257 PolarHBondContact O-N 3.3Å; A257-E259 VanDerWaalsContact C-N 3.28Å; A257-E259 PolarHBondContact O-N 2.94Å; A257-T260 WeakPolarHBondContact CA-OG1 3.39Å; A257-T260 PolarHBondContact O-N 3.14Å; A257-T260 PolarHBondContact O-OG1 2.96Å; A257-D261 PolarHBondContact O-N 3.39Å
258	E	48.4	Very low	49.1	Very low	105 Å²	105	71.8 Å²	71.8	49%	0.491	35%	0.349	S	S	.	.	H	α-helix	trans	-62	-36.1	173.7	-91.9	177.8	152.6	0	0	112.4	V254 H262	V254-E258 PolarHBondContact O-N 3.09Å; V254-E258 VanDerWaalsContact O-N 3.1Å; E258-H262 PolarHBondContact O-CD2 3.27Å; E258-H262 VanDerWaalsContact O-CD2 3.28Å
259	E	50.2	Low	50.5	Low	70 Å²	70	61.6 Å²	61.6	33%	0.327	31%	0.311	S	S	.	.	H	α-helix	trans	-73.4	-36.5	177.5	-158.2	161	-167.4	0	0	112.1	S255 M256 A257 D261 H262 L263	S255-E259 PolarHBondContact O-N 3.33Å; M256-E259 PolarHBondContact O-N 3.43Å; A257-E259 VanDerWaalsContact C-N 3.28Å; A257-E259 PolarHBondContact O-N 2.94Å; E259-D261 VanDerWaalsContact C-N 3.35Å; E259-D261 PolarHBondContact O-N 3.24Å; E259-H262 PolarHBondContact O-N 2.86Å; E259-L263 WeakPolarHBondContact O-CD1 3.3Å; E259-L263 WeakPolarHBondContact O-CG 3.39Å
260	T	50.4	Low	51.8	Low	45 Å²	45	55.5 Å²	55.5	28%	0.276	29%	0.289	S	S	.	.	H	α-helix	trans	-68.3	-25.1	176.6	53.7	0	0	0	0	115.2	M256 A257 L263 I264	M256-T260 VanDerWaalsContact O-CG2 3.24Å; M256-T260 WeakPolarHBondContact O-CG2 3.46Å; M256-T260 PolarHBondContact O-N 3.05Å; M256-T260 PolarHBondContact O-OG1 3.45Å; A257-T260 WeakPolarHBondContact CA-OG1 3.39Å; A257-T260 PolarHBondContact O-N 3.14Å; A257-T260 PolarHBondContact O-OG1 2.96Å; T260-L263 WeakPolarHBondContact O-CB 3.45Å; T260-L263 PolarHBondContact O-N 2.93Å; T260-I264 WeakPolarHBondContact O-CG1 3.45Å; T260-I264 PolarHBondContact O-N 3.02Å
261	D	53.6	Low	53.4	Low	4 Å²	4	51.5 Å²	51.5	2%	0.021	28%	0.281	C	S	.	.	H	α-helix	trans	-76.4	-33	179.5	-70.8	-24.8	0	0	0	112.1	A257 E259 L263 L265 P320 R324 R327	A257-D261 PolarHBondContact O-N 3.39Å; E259-D261 VanDerWaalsContact C-N 3.35Å; E259-D261 PolarHBondContact O-N 3.24Å; D261-L263 PolarHBondContact O-N 2.94Å; D261-L265 PolarHBondContact O-N 2.82Å; D261-P320 HydrophobicContact CB-CB 3.47Å; D261-P320 VanDerWaalsContact CB-CB 3.47Å; D261-P320 HydrophobicContact CB-CG 3.84Å; D261-R324 WeakPolarHBondContact OD2-CD 3.42Å; D261-R324 WeakPolarHBondContact OD2-CG 3.28Å; D261-R324 IonicContact OD2-NE 2.73Å; D261-R327 IonicContact OD1-NH1 3Å
262	H	56.8	Low	55	Low	18 Å²	18	50.4 Å²	50.4	8%	0.083	27%	0.266	C	S	.	.	H	α-helix	trans	-63.5	-30.8	171.5	-77.4	-114.2	0	0	0	111.5	F67 H68 E258 E259 L266	F67-H262 AromaticContact CD1-CE1 3.92Å; F67-H262 AromaticContact CD1-ND1 3.39Å; F67-H262 WeakPolarHBondContact CD1-ND1 3.19Å; F67-H262 AromaticContact CE1-CE1 3.79Å; F67-H262 AromaticContact CE1-ND1 3.16Å; F67-H262 WeakPolarHBondContact CE1-ND1 3.45Å; H68-H262 AromaticContact CE1-CE1 3.42Å; H68-H262 PolarHBondContact CE1-CE1 3.31Å; H68-H262 VanDerWaalsContact CE1-CE1 3.42Å; H68-H262 AromaticContact NE2-CE1 3.52Å; E258-H262 PolarHBondContact O-CD2 3.27Å; E258-H262 VanDerWaalsContact O-CD2 3.28Å; E259-H262 PolarHBondContact O-N 2.86Å; H262-L266 VanDerWaalsContact O-CD1 3.23Å; H262-L266 WeakPolarHBondContact O-CD1 3.2Å; H262-L266 VanDerWaalsContact O-CG 3.29Å; H262-L266 WeakPolarHBondContact O-CG 3.23Å; H262-L266 PolarHBondContact O-N 3.3Å; H262-L266 VanDerWaalsContact O-N 3.09Å
263	L	58.5	Low	56.6	Low	15 Å²	15	44.1 Å²	44.1	8%	0.079	24%	0.236	C	C	.	.	H	α-helix	trans	-75.4	-35.2	-178.1	-66.2	161.5	0	0	0	113.8	I138 V218 L222 E259 T260 D261 L266 A267	I138-L263 HydrophobicContact CD1-CD1 3.65Å; I138-L263 HydrophobicContact CD1-CD2 3.16Å; I138-L263 HydrophobicContact CD1-CG 3.87Å; V218-L263 HydrophobicContact CG1-CD2 3.36Å; L222-L263 HydrophobicContact CD1-CB 4.44Å; L222-L263 HydrophobicContact CD1-CD1 3.39Å; L222-L263 HydrophobicContact CD1-CD2 4.38Å; L222-L263 HydrophobicContact CD1-CG 4.26Å; L222-L263 HydrophobicContact CD2-CD1 3.84Å; L222-L263 HydrophobicContact CG-CD1 4.19Å; E259-L263 WeakPolarHBondContact O-CD1 3.3Å; E259-L263 WeakPolarHBondContact O-CG 3.39Å; T260-L263 WeakPolarHBondContact O-CB 3.45Å; T260-L263 PolarHBondContact O-N 2.93Å; D261-L263 PolarHBondContact O-N 2.94Å; L263-L266 HydrophobicContact CD2-CD1 4.38Å; L263-A267 WeakPolarHBondContact O-CB 3.46Å; L263-A267 PolarHBondContact O-N 3.34Å
264	I	61.5	Low	58.2	Low	39 Å²	39	37.9 Å²	37.9	20%	0.2	22%	0.215	C	C	.	.	H	α-helix	trans	-70	-41.2	175.4	-66.1	157.4	0	0	0	110	T260 L266 A267 I268 L323	T260-I264 WeakPolarHBondContact O-CG1 3.45Å; T260-I264 PolarHBondContact O-N 3.02Å; I264-L266 VanDerWaalsContact C-N 3.34Å; I264-L266 PolarHBondContact O-N 2.98Å; I264-A267 PolarHBondContact O-N 2.87Å; I264-I268 HydrophobicContact CG2-CD1 3.87Å; I264-I268 HydrophobicContact CG2-CG1 4.5Å; I264-I268 VanDerWaalsContact O-CG1 3.3Å; I264-I268 WeakPolarHBondContact O-CG1 3.48Å; I264-I268 PolarHBondContact O-N 3.4Å; I264-L323 HydrophobicContact CB-CD1 4.21Å; I264-L323 HydrophobicContact CG2-CD1 3.82Å; I264-L323 HydrophobicContact CG2-CD2 4.35Å
265	L	62	Low	59.8	Low	1 Å²	1	38.4 Å²	38.4	1%	0.005	22%	0.218	C	C	.	.	H	α-helix	trans	-59.4	-45.8	174.6	178.6	65.2	0	0	0	111.3	D261 I268 M269 V314 F315 L318	D261-L265 PolarHBondContact O-N 2.82Å; L265-I268 PolarHBondContact O-N 2.93Å; L265-M269 HydrophobicContact CG-SD 4.28Å; L265-M269 WeakPolarHBondContact O-CB 3.49Å; L265-M269 VanDerWaalsContact O-CG 3.3Å; L265-M269 WeakPolarHBondContact O-CG 3.21Å; L265-M269 PolarHBondContact O-N 3.44Å; L265-V314 HydrophobicContact CD1-CG1 4.17Å; L265-F315 HydrophobicContact CD1-CD2 4.46Å; L265-F315 HydrophobicContact CD2-CD2 3.7Å; L265-F315 HydrophobicContact CD2-CE2 3.74Å; L265-L318 HydrophobicContact CD1-CB 4.33Å
266	L	63.9	Low	61.3	Low	7 Å²	7	35.1 Å²	35.1	4%	0.037	20%	0.196	C	C	.	.	H	α-helix	trans	-60.7	-42.9	174.1	-78.1	156.5	0	0	0	113.1	F67 M130 R134 H262 L263 I264 I268 M269 T270	F67-L266 HydrophobicContact CE2-CD1 4Å; F67-L266 HydrophobicContact CE2-CD2 3.71Å; F67-L266 HydrophobicContact CE2-CG 3.88Å; F67-L266 HydrophobicContact CZ-CG 4.34Å; M130-L266 HydrophobicContact CB-CD2 4.28Å; R134-L266 HydrophobicContact CB-CD1 3.9Å; R134-L266 VanDerWaalsContact CD-CD1 3.42Å; R134-L266 HydrophobicContact CG-CD1 3.27Å; R134-L266 HydrophobicContact CG-CD2 4.39Å; R134-L266 HydrophobicContact CG-CG 4.44Å; H262-L266 VanDerWaalsContact O-CD1 3.23Å; H262-L266 WeakPolarHBondContact O-CD1 3.2Å; H262-L266 VanDerWaalsContact O-CG 3.29Å; H262-L266 WeakPolarHBondContact O-CG 3.23Å; H262-L266 PolarHBondContact O-N 3.3Å; H262-L266 VanDerWaalsContact O-N 3.09Å; L263-L266 HydrophobicContact CD2-CD1 4.38Å; I264-L266 VanDerWaalsContact C-N 3.34Å; I264-L266 PolarHBondContact O-N 2.98Å; L266-I268 VanDerWaalsContact C-N 3.33Å; L266-I268 PolarHBondContact O-N 2.74Å; L266-M269 PolarHBondContact O-N 3.34Å; L266-T270 VanDerWaalsContact O-CB 3.31Å; L266-T270 WeakPolarHBondContact O-CB 3.3Å; L266-T270 PolarHBondContact O-N 3.28Å; L266-T270 PolarHBondContact O-OG1 2.91Å
267	A	64.8	Low	62.6	Low	29 Å²	29	31.9 Å²	31.9	24%	0.24	18%	0.179	C	C	.	.	H	α-helix	trans	-62.7	-41.3	176.8	0	0	0	0	0	111.6	L263 I264 T270 I271	L263-A267 WeakPolarHBondContact O-CB 3.46Å; L263-A267 PolarHBondContact O-N 3.34Å; I264-A267 PolarHBondContact O-N 2.87Å; A267-T270 WeakPolarHBondContact O-CB 3.32Å; A267-T270 PolarHBondContact O-N 3.25Å; A267-I271 VanDerWaalsContact O-CG1 3.28Å; A267-I271 WeakPolarHBondContact O-CG1 3.29Å; A267-I271 PolarHBondContact O-N 3.05Å
268	I	65.9	Low	64.2	Low	45 Å²	45	32.9 Å²	32.9	23%	0.231	18%	0.179	C	C	.	.	H	α-helix	trans	-70.5	-43.8	177.8	-61.4	166.4	0	0	0	111.1	I264 L265 L266 T270 I271 T272 V314 L318	I264-I268 HydrophobicContact CG2-CD1 3.87Å; I264-I268 HydrophobicContact CG2-CG1 4.5Å; I264-I268 VanDerWaalsContact O-CG1 3.3Å; I264-I268 WeakPolarHBondContact O-CG1 3.48Å; I264-I268 PolarHBondContact O-N 3.4Å; L265-I268 PolarHBondContact O-N 2.93Å; L266-I268 VanDerWaalsContact C-N 3.33Å; L266-I268 PolarHBondContact O-N 2.74Å; I268-T270 PolarHBondContact O-N 3.49Å; I268-I271 PolarHBondContact O-N 3.41Å; I268-I271 VanDerWaalsContact O-N 3.14Å; I268-T272 PolarHBondContact O-N 2.81Å; I268-T272 PolarHBondContact O-OG1 2.79Å; I268-T272 VanDerWaalsContact O-OG1 3.06Å; I268-V314 HydrophobicContact CB-CG1 4.4Å; I268-V314 HydrophobicContact CG2-CG1 3.88Å; I268-V314 HydrophobicContact CG2-CG2 4.5Å; I268-L318 HydrophobicContact CB-CD1 4.29Å; I268-L318 HydrophobicContact CD1-CD1 3.79Å; I268-L318 HydrophobicContact CD1-CD2 4.02Å; I268-L318 HydrophobicContact CD1-CG 4.34Å; I268-L318 HydrophobicContact CG2-CD1 3.57Å
269	M	67.6	Low	65.6	Low	3 Å²	3	30.1 Å²	30.1	2%	0.015	17%	0.17	C	C	.	.	H	α-helix	trans	-56.4	-39.9	172.5	-72.4	-180	73.7	0	0	111.3	L74 L127 M130 L265 L266 T272 F273 V314	L74-M269 HydrophobicContact CD2-CE 3.58Å; L127-M269 HydrophobicContact CD2-CE 3.69Å; M130-M269 HydrophobicContact CE-CE 4.12Å; L265-M269 HydrophobicContact CG-SD 4.28Å; L265-M269 WeakPolarHBondContact O-CB 3.49Å; L265-M269 VanDerWaalsContact O-CG 3.3Å; L265-M269 WeakPolarHBondContact O-CG 3.21Å; L265-M269 PolarHBondContact O-N 3.44Å; L266-M269 PolarHBondContact O-N 3.34Å; M269-T272 PolarHBondContact O-N 2.73Å; M269-F273 WeakPolarHBondContact O-CB 3.34Å; M269-F273 PolarHBondContact O-N 2.84Å; M269-V314 HydrophobicContact CG-CG1 3.7Å
270	T	69.8	Low	66.9	Low	11 Å²	11	26.8 Å²	26.8	7%	0.067	16%	0.155	C	C	.	.	H	α-helix	trans	-66.6	-39.6	177.3	-57.1	0	0	0	0	112.8	V211 L212 N215 L266 A267 I268 A274	V211-T270 HydrophobicContact CG1-CG2 3.66Å; L212-T270 HydrophobicContact CD2-CG2 3.68Å; L212-T270 HydrophobicContact CG-CG2 4.43Å; N215-T270 HydrophobicContact CB-CG2 4.48Å; N215-T270 VanDerWaalsContact CG-OG1 3.31Å; N215-T270 PolarHBondContact ND2-OG1 2.96Å; L266-T270 VanDerWaalsContact O-CB 3.31Å; L266-T270 WeakPolarHBondContact O-CB 3.3Å; L266-T270 PolarHBondContact O-N 3.28Å; L266-T270 PolarHBondContact O-OG1 2.91Å; A267-T270 WeakPolarHBondContact O-CB 3.32Å; A267-T270 PolarHBondContact O-N 3.25Å; I268-T270 PolarHBondContact O-N 3.49Å; T270-A274 WeakPolarHBondContact O-CB 3.16Å; T270-A274 PolarHBondContact O-N 2.85Å
271	I	68.3	Low	68.2	Low	107 Å²	107	24.9 Å²	24.9	55%	0.549	14%	0.143	S	C	.	.	H	α-helix	trans	-66.3	-48.2	176.3	-69.5	163.3	0	0	0	109.9	A267 I268 F273 A274 V275	A267-I271 VanDerWaalsContact O-CG1 3.28Å; A267-I271 WeakPolarHBondContact O-CG1 3.29Å; A267-I271 PolarHBondContact O-N 3.05Å; I268-I271 PolarHBondContact O-N 3.41Å; I268-I271 VanDerWaalsContact O-N 3.14Å; I271-F273 VanDerWaalsContact C-N 3.3Å; I271-F273 PolarHBondContact O-N 3.14Å; I271-A274 PolarHBondContact O-N 3.32Å; I271-V275 HydrophobicContact CG2-CG2 4.44Å; I271-V275 VanDerWaalsContact O-CG2 3.3Å; I271-V275 WeakPolarHBondContact O-CG2 3.31Å; I271-V275 PolarHBondContact O-N 3.45Å
272	T	68.4	Low	69.3	Low	20 Å²	20	29.3 Å²	29.3	12%	0.123	17%	0.166	C	C	.	.	H	α-helix	trans	-56.3	-47.8	176.2	-60.1	0	0	0	0	111	I268 M269 A274 V275 C276 I310 V314	I268-T272 PolarHBondContact O-N 2.81Å; I268-T272 PolarHBondContact O-OG1 2.79Å; I268-T272 VanDerWaalsContact O-OG1 3.06Å; M269-T272 PolarHBondContact O-N 2.73Å; T272-A274 PolarHBondContact O-N 3.11Å; T272-V275 PolarHBondContact O-N 3.49Å; T272-C276 WeakPolarHBondContact O-CB 3.3Å; T272-C276 PolarHBondContact O-N 2.78Å; T272-C276 PolarHBondContact O-SG 3.36Å; T272-I310 HydrophobicContact CG2-CB 3.83Å; T272-I310 HydrophobicContact CG2-CG2 3.36Å; T272-V314 HydrophobicContact CG2-CG2 4.49Å
273	F	72.1	Confident	70.2	Confident	1 Å²	1	29.8 Å²	29.8	0%	0.004	17%	0.167	C	C	.	.	H	α-helix	trans	-58.4	-47.2	177.9	175.5	-109.8	0	0	0	113	M124 L127 I208 V211 M269 I271 C276 S277 N307	M124-F273 HydrophobicContact CB-CE2 4.13Å; M124-F273 HydrophobicContact CB-CZ 4.08Å; M124-F273 HydrophobicContact CE-CD2 4.29Å; M124-F273 HydrophobicContact CE-CE2 3.55Å; M124-F273 HydrophobicContact CE-CZ 4.11Å; M124-F273 HydrophobicContact CG-CE2 3.71Å; M124-F273 HydrophobicContact CG-CZ 3.97Å; M124-F273 HydrophobicContact SD-CD2 4.27Å; M124-F273 HydrophobicContact SD-CE1 4.29Å; M124-F273 HydrophobicContact SD-CE2 3.09Å; M124-F273 WeakPolarHBondContact SD-CE2 3.2Å; M124-F273 HydrophobicContact SD-CZ 3.1Å; M124-F273 WeakPolarHBondContact SD-CZ 3.36Å; L127-F273 HydrophobicContact CD1-CB 4.36Å; L127-F273 HydrophobicContact CD1-CD2 3.23Å; L127-F273 HydrophobicContact CD1-CE2 3.42Å; L127-F273 VanDerWaalsContact CD1-CE2 3.42Å; L127-F273 HydrophobicContact CD1-CG 3.93Å; L127-F273 HydrophobicContact CD1-CZ 4.31Å; I208-F273 HydrophobicContact CB-CE1 4.3Å; I208-F273 HydrophobicContact CG1-CD1 4.29Å; I208-F273 HydrophobicContact CG1-CE1 3.58Å; I208-F273 HydrophobicContact CG1-CZ 4.1Å; V211-F273 HydrophobicContact CG2-CE1 4.37Å; M269-F273 WeakPolarHBondContact O-CB 3.34Å; M269-F273 PolarHBondContact O-N 2.84Å; I271-F273 VanDerWaalsContact C-N 3.3Å; I271-F273 PolarHBondContact O-N 3.14Å; F273-C276 PolarHBondContact O-N 3.43Å; F273-S277 WeakPolarHBondContact O-CB 3.37Å; F273-S277 PolarHBondContact O-N 2.95Å; F273-S277 PolarHBondContact O-OG 3.42Å; F273-N307 WeakPolarHBondContact CA-OD1 3.37Å
274	A	71.4	Confident	70.9	Confident	12 Å²	12	29.6 Å²	29.6	10%	0.099	17%	0.168	C	C	.	.	H	α-helix	trans	-61.6	-45.7	176.5	0	0	0	0	0	111	T270 I271 T272 C276 S277 L278	T270-A274 WeakPolarHBondContact O-CB 3.16Å; T270-A274 PolarHBondContact O-N 2.85Å; I271-A274 PolarHBondContact O-N 3.32Å; T272-A274 PolarHBondContact O-N 3.11Å; A274-C276 VanDerWaalsContact C-N 3.35Å; A274-C276 PolarHBondContact O-N 2.81Å; A274-S277 PolarHBondContact O-N 3.31Å; A274-L278 HydrophobicContact CB-CD1 4.05Å; A274-L278 WeakPolarHBondContact O-CB 3.41Å; A274-L278 WeakPolarHBondContact O-CD1 3.33Å; A274-L278 WeakPolarHBondContact O-CG 3.23Å; A274-L278 PolarHBondContact O-N 2.86Å
275	V	73.3	Confident	71.6	Confident	92 Å²	92	32.8 Å²	32.8	56%	0.558	18%	0.179	S	C	*	.	H	α-helix	trans	-64.1	-37.9	180	172.5	0	0	0	0	112.1	I271 T272 P279	I271-V275 HydrophobicContact CG2-CG2 4.44Å; I271-V275 VanDerWaalsContact O-CG2 3.3Å; I271-V275 WeakPolarHBondContact O-CG2 3.31Å; I271-V275 PolarHBondContact O-N 3.45Å; T272-V275 PolarHBondContact O-N 3.49Å; V275-P279 WeakPolarHBondContact O-CD 2.78Å; V275-P279 WeakPolarHBondContact O-CG 2.81Å
276	C	72.3	Confident	72.1	Confident	5 Å²	5	36.9 Å²	36.9	3%	0.034	20%	0.199	C	C	.	.	H	α-helix	trans	-79.3	-27.4	-178.8	-61.2	0	0	0	0	113.1	T272 F273 A274 F303 N307	T272-C276 WeakPolarHBondContact O-CB 3.3Å; T272-C276 PolarHBondContact O-N 2.78Å; T272-C276 PolarHBondContact O-SG 3.36Å; F273-C276 PolarHBondContact O-N 3.43Å; A274-C276 VanDerWaalsContact C-N 3.35Å; A274-C276 PolarHBondContact O-N 2.81Å; C276-F303 CarbonylContact O-C 3.58Å; C276-N307 HydrophobicContact CB-CB 3.9Å
277	S	71.8	Confident	71.9	Confident	0 Å²	0	41.8 Å²	41.8	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-103	-30.4	-170.5	-48.4	0	0	0	0	113.7	M124 F273 A274 P279 F280 T281	M124-S277 WeakPolarHBondContact CE-OG 3.33Å; F273-S277 WeakPolarHBondContact O-CB 3.37Å; F273-S277 PolarHBondContact O-N 2.95Å; F273-S277 PolarHBondContact O-OG 3.42Å; A274-S277 PolarHBondContact O-N 3.31Å; S277-P279 VanDerWaalsContact C-CD 3.5Å; S277-F280 PolarHBondContact O-N 2.86Å; S277-T281 PolarHBondContact O-N 2.64Å; S277-T281 VanDerWaalsContact O-N 3.16Å
278	L	76.4	Confident	71.4	Confident	62 Å²	62	44.6 Å²	44.6	33%	0.325	23%	0.233	S	C	.	.	H	α-helix	trans	-59.3	-42.9	179	-75	170.2	0	0	0	113.6	I208 A274 F280 T281 I282	I208-L278 HydrophobicContact CD1-CD2 4.39Å; I208-L278 HydrophobicContact CG2-CD2 4.24Å; A274-L278 HydrophobicContact CB-CD1 4.05Å; A274-L278 WeakPolarHBondContact O-CB 3.41Å; A274-L278 WeakPolarHBondContact O-CD1 3.33Å; A274-L278 WeakPolarHBondContact O-CG 3.23Å; A274-L278 PolarHBondContact O-N 2.86Å; L278-F280 PolarHBondContact O-N 2.98Å; L278-T281 WeakPolarHBondContact CA-OG1 3.38Å; L278-T281 PolarHBondContact O-N 3.15Å; L278-T281 VanDerWaalsContact O-N 3.11Å; L278-T281 PolarHBondContact O-OG1 3.3Å; L278-I282 WeakPolarHBondContact O-CG1 3.22Å; L278-I282 PolarHBondContact O-N 3.22Å
279	P	78.7	Confident	70.8	Confident	46 Å²	46	47.7 Å²	47.7	30%	0.299	25%	0.254	S	S	.	.	H	α-helix	trans	-55.8	-41.1	178.1	-25.5	34.9	0	0	0	112.4	V275 S277 F283	V275-P279 WeakPolarHBondContact O-CD 2.78Å; V275-P279 WeakPolarHBondContact O-CG 2.81Å; S277-P279 VanDerWaalsContact C-CD 3.5Å; P279-F283 WeakPolarHBondContact O-CB 3.49Å; P279-F283 PolarHBondContact O-N 2.97Å
280	F	77.4	Confident	70.2	Confident	1 Å²	1	52.5 Å²	52.5	0%	0.004	29%	0.288	C	S	.	.	H	α-helix	trans	-66.6	-44.2	176.6	177.1	-92.1	0	0	0	112.4	F188 L197 Y200 L204 S277 L278 F283 A284 L301 L304	F188-F280 HydrophobicContact CD1-CE2 4.39Å; F188-F280 AromaticContact CE1-CE2 3.63Å; F188-F280 HydrophobicContact CE1-CE2 3.63Å; F188-F280 AromaticContact CE1-CZ 3.54Å; F188-F280 HydrophobicContact CE1-CZ 3.54Å; F188-F280 AromaticContact CZ-CE2 3.97Å; F188-F280 HydrophobicContact CZ-CE2 3.97Å; F188-F280 AromaticContact CZ-CZ 3.75Å; F188-F280 HydrophobicContact CZ-CZ 3.75Å; L197-F280 HydrophobicContact CD1-CZ 4.33Å; Y200-F280 AromaticContact CD1-CE1 3.75Å; Y200-F280 HydrophobicContact CD1-CE1 3.75Å; Y200-F280 AromaticContact CD1-CZ 3.92Å; Y200-F280 HydrophobicContact CD1-CZ 3.92Å; Y200-F280 AromaticContact CE1-CE1 3.54Å; Y200-F280 HydrophobicContact CE1-CE1 3.54Å; Y200-F280 AromaticContact CE1-CZ 3.73Å; Y200-F280 HydrophobicContact CE1-CZ 3.73Å; L204-F280 HydrophobicContact CD1-CD1 3.73Å; L204-F280 HydrophobicContact CD1-CE1 3.71Å; S277-F280 PolarHBondContact O-N 2.86Å; L278-F280 PolarHBondContact O-N 2.98Å; F280-F283 WeakPolarHBondContact O-CB 3.19Å; F280-F283 PolarHBondContact O-N 3.3Å; F280-A284 PolarHBondContact O-N 3.35Å; F280-L301 HydrophobicContact CD2-CD2 4.22Å; F280-L301 HydrophobicContact CE2-CD2 3.85Å; F280-L304 HydrophobicContact CB-CB 4.39Å; F280-L304 HydrophobicContact CB-CD1 4.46Å; F280-L304 HydrophobicContact CD1-CD2 4.15Å; F280-L304 HydrophobicContact CD2-CD2 4Å; F280-L304 HydrophobicContact CE1-CD2 4.36Å; F280-L304 HydrophobicContact CE2-CD2 4.2Å; F280-L304 HydrophobicContact CG-CD1 4.5Å; F280-L304 HydrophobicContact CG-CD2 3.98Å; F280-L304 HydrophobicContact CZ-CD2 4.39Å
281	T	76.8	Confident	69.1	Low	4 Å²	4	57.6 Å²	57.6	3%	0.025	32%	0.324	C	S	.	.	H	α-helix	trans	-64.4	-44	178.6	58.7	0	0	0	0	112.3	L204 L205 I208 S277 L278 F283 A284 Y285	L204-T281 HydrophobicContact CB-CG2 3.97Å; L205-T281 HydrophobicContact CB-CG2 4.46Å; I208-T281 HydrophobicContact CD1-CG2 3.96Å; S277-T281 PolarHBondContact O-N 2.64Å; S277-T281 VanDerWaalsContact O-N 3.16Å; L278-T281 WeakPolarHBondContact CA-OG1 3.38Å; L278-T281 PolarHBondContact O-N 3.15Å; L278-T281 VanDerWaalsContact O-N 3.11Å; L278-T281 PolarHBondContact O-OG1 3.3Å; T281-F283 VanDerWaalsContact C-N 3.29Å; T281-F283 PolarHBondContact O-N 3.16Å; T281-A284 PolarHBondContact O-N 3.47Å; T281-Y285 WeakPolarHBondContact O-CD2 3.48Å; T281-Y285 PolarHBondContact O-N 3.44Å
282	I	78	Confident	68.3	Low	98 Å²	98	60.1 Å²	60.1	50%	0.503	33%	0.327	S	S	.	.	H	α-helix	trans	-58.6	-47.6	176.7	-67.3	165.8	0	0	0	109.2	L278 A284 Y285 M286	L278-I282 WeakPolarHBondContact O-CG1 3.22Å; L278-I282 PolarHBondContact O-N 3.22Å; I282-A284 PolarHBondContact O-N 3.18Å; I282-Y285 PolarHBondContact O-N 3.26Å; I282-Y285 VanDerWaalsContact O-N 3.12Å; I282-M286 HydrophobicContact CG2-CG 4.16Å; I282-M286 HydrophobicContact CG2-SD 3.82Å; I282-M286 WeakPolarHBondContact O-CG 3.17Å; I282-M286 PolarHBondContact O-N 2.68Å
283	F	74.8	Confident	67.8	Low	27 Å²	27	61.4 Å²	61.4	12%	0.118	33%	0.33	C	S	.	.	H	α-helix	trans	-57.3	-44.4	178.2	168.7	-105.9	0	0	0	113	H191 P279 F280 T281 Y285 M286 D297 A300	H191-F283 HydrophobicContact CB-CZ 4.28Å; H191-F283 AromaticContact CE1-CE1 3.7Å; H191-F283 AromaticContact CE1-CE2 3.51Å; H191-F283 AromaticContact CE1-CZ 3.2Å; H191-F283 WeakPolarHBondContact CE1-CZ 3.49Å; H191-F283 AromaticContact CG-CZ 3.51Å; H191-F283 AromaticContact ND1-CE1 3.16Å; H191-F283 WeakPolarHBondContact ND1-CE1 3.25Å; H191-F283 AromaticContact ND1-CE2 3.75Å; H191-F283 AromaticContact ND1-CZ 2.92Å; H191-F283 WeakPolarHBondContact ND1-CZ 3.31Å; H191-F283 AromaticContact NE2-CZ 3.95Å; P279-F283 WeakPolarHBondContact O-CB 3.49Å; P279-F283 PolarHBondContact O-N 2.97Å; F280-F283 WeakPolarHBondContact O-CB 3.19Å; F280-F283 PolarHBondContact O-N 3.3Å; T281-F283 VanDerWaalsContact C-N 3.29Å; T281-F283 PolarHBondContact O-N 3.16Å; F283-Y285 PolarHBondContact O-N 2.98Å; F283-Y285 VanDerWaalsContact O-N 3.16Å; F283-M286 PolarHBondContact O-N 3.39Å; F283-M286 VanDerWaalsContact O-N 3.1Å; F283-D297 HydrophobicContact CE1-CB 4.33Å; F283-D297 HydrophobicContact CE2-CB 4.39Å; F283-D297 WeakPolarHBondContact CE2-OD1 3.43Å; F283-D297 HydrophobicContact CZ-CB 3.8Å; F283-D297 WeakPolarHBondContact CZ-OD1 3.2Å; F283-A300 HydrophobicContact CB-CB 4.21Å; F283-A300 HydrophobicContact CD1-CB 4.21Å; F283-A300 HydrophobicContact CG-CB 4.2Å
284	A	74.1	Confident	67.2	Low	12 Å²	12	65.8 Å²	65.8	10%	0.099	35%	0.351	C	S	.	.	H	α-helix	trans	-63.1	-21.8	179.2	0	0	0	0	0	114	L197 A201 F280 T281 I282	L197-A284 HydrophobicContact CG-CB 4.46Å; A201-A284 HydrophobicContact CB-CB 3.4Å; F280-A284 PolarHBondContact O-N 3.35Å; T281-A284 PolarHBondContact O-N 3.47Å; I282-A284 PolarHBondContact O-N 3.18Å
285	Y	75.3	Confident	66.7	Low	106 Å²	106	73.8 Å²	73.8	42%	0.416	38%	0.384	S	S	.	.	H	α-helix	trans	-96.5	-17.1	174.3	-67.2	-70.9	0	0	0	114	A201 T202 L205 T281 I282 F283	A201-Y285 HydrophobicContact CB-CE2 4.2Å; T202-Y285 WeakPolarHBondContact CA-OH 3.46Å; T202-Y285 HydrophobicContact CG2-CE1 4.35Å; T202-Y285 WeakPolarHBondContact CG2-OH 3.35Å; T202-Y285 PolarHBondContact N-OH 2.79Å; L205-Y285 HydrophobicContact CD2-CE2 4.15Å; T281-Y285 WeakPolarHBondContact O-CD2 3.48Å; T281-Y285 PolarHBondContact O-N 3.44Å; I282-Y285 PolarHBondContact O-N 3.26Å; I282-Y285 VanDerWaalsContact O-N 3.12Å; F283-Y285 PolarHBondContact O-N 2.98Å; F283-Y285 VanDerWaalsContact O-N 3.16Å
286	M	72.3	Confident	66.2	Low	87 Å²	87	77.5 Å²	77.5	43%	0.429	39%	0.388	S	S	.	.			trans	-73.3	130.7	177.8	-76.3	-175.6	70.8	0	0	110.6	I282 F283 E288	I282-M286 HydrophobicContact CG2-CG 4.16Å; I282-M286 HydrophobicContact CG2-SD 3.82Å; I282-M286 WeakPolarHBondContact O-CG 3.17Å; I282-M286 PolarHBondContact O-N 2.68Å; F283-M286 PolarHBondContact O-N 3.39Å; F283-M286 VanDerWaalsContact O-N 3.1Å; M286-E288 HydrophobicContact CE-CG 3.99Å
287	N	60	Low	66	Low	110 Å²	110	77.6 Å²	77.6	59%	0.588	39%	0.388	S	S	*	.			trans	-112.7	64.5	176.8	-165.4	39.7	0	0	0	109.5
288	E	54.8	Low	65.9	Low	88 Å²	88	78.3 Å²	78.3	41%	0.411	39%	0.392	S	S	.	.			trans	-94.1	159.2	179.4	-85.5	-153	178.1	0	0	113.9	M286 K293	M286-E288 HydrophobicContact CE-CG 3.99Å; E288-K293 VanDerWaalsContact O-CE 3.23Å; E288-K293 WeakPolarHBondContact O-CE 3.21Å
289	T	53.2	Low	65.7	Low	110 Å²	110	79 Å²	79	68%	0.675	39%	0.393	S	S	*	.			trans	-62	144.9	-176.6	46.8	0	0	0	0	114	S291 R292	T289-S291 PolarHBondContact O-N 3.18Å; T289-S291 VanDerWaalsContact O-N 3.11Å; T289-R292 PolarHBondContact O-N 3.44Å
290	S	54.2	Low	65.5	Low	103 Å²	103	77.2 Å²	77.2	72%	0.72	38%	0.382	S	S	*	.	G	3₁₀ helix	trans	-48.6	-34.7	-163.7	30.6	0	0	0	0	118.4	K293	S290-K293 WeakPolarHBondContact O-CB 3.5Å; S290-K293 PolarHBondContact O-N 3.36Å
291	S	47.8	Very low	65.3	Low	118 Å²	118	77.2 Å²	77.2	83%	0.825	38%	0.382	S	S	*	.	G	3₁₀ helix	trans	-83.9	-26.2	-173.9	-177.1	0	0	0	0	114.4	T289 K293	T289-S291 PolarHBondContact O-N 3.18Å; T289-S291 VanDerWaalsContact O-N 3.11Å; S291-K293 VanDerWaalsContact C-N 3.25Å
292	R	51	Low	65.4	Low	160 Å²	160	79 Å²	79	60%	0.604	39%	0.388	S	S	*	.	G	3₁₀ helix	trans	-86.6	3.2	172.6	-164.2	175.5	-70.3	-176.2	-0.7	111.5	T289	T289-R292 PolarHBondContact O-N 3.44Å
293	K	58.5	Low	65.3	Low	47 Å²	47	77.8 Å²	77.8	20%	0.204	38%	0.38	C	S	.	.	H	α-helix	trans	-78.8	-69.2	-175.6	-128.1	163.8	-170.6	-167.2	0	111.2	H191 E288 S290 S291 K295 W296 D297	H191-K293 WeakPolarHBondContact CD2-CE 3.44Å; H191-K293 PolarHBondContact CD2-NZ 3.36Å; H191-K293 WeakPolarHBondContact NE2-CE 3.14Å; H191-K293 PolarHBondContact NE2-NZ 3.45Å; E288-K293 VanDerWaalsContact O-CE 3.23Å; E288-K293 WeakPolarHBondContact O-CE 3.21Å; S290-K293 WeakPolarHBondContact O-CB 3.5Å; S290-K293 PolarHBondContact O-N 3.36Å; S291-K293 VanDerWaalsContact C-N 3.25Å; K293-K295 VanDerWaalsContact C-N 3.32Å; K293-K295 PolarHBondContact O-N 3.31Å; K293-W296 PolarHBondContact O-N 3.25Å; K293-D297 VanDerWaalsContact C-CG 3.5Å; K293-D297 VanDerWaalsContact O-CG 3.22Å; K293-D297 PolarHBondContact O-N 3.27Å
294	E	58.6	Low	65.4	Low	94 Å²	94	76.7 Å²	76.7	44%	0.439	38%	0.375	S	S	.	.	H	α-helix	trans	-50.8	-40.2	-168.5	-70.4	-173.6	133.2	0	0	116.4	L298	E294-L298 PolarHBondContact O-N 3.05Å
295	K	60.5	Low	65.2	Low	180 Å²	180	77.5 Å²	77.5	78%	0.783	38%	0.38	S	S	*	.	H	α-helix	trans	-68	-36.6	179.8	-72.4	-177.3	179.8	175.9	0	112.8	K293 Q299	K293-K295 VanDerWaalsContact C-N 3.32Å; K293-K295 PolarHBondContact O-N 3.31Å; K295-Q299 WeakPolarHBondContact O-CB 3.27Å; K295-Q299 PolarHBondContact O-N 3.14Å
296	W	63.2	Low	65.2	Low	169 Å²	169	74.4 Å²	74.4	64%	0.64	37%	0.37	S	S	*	.	H	α-helix	trans	-80.6	-31.5	179.4	-68.4	84.7	0	0	0	111.1	K293 Q299 A300	K293-W296 PolarHBondContact O-N 3.25Å; W296-Q299 PolarHBondContact O-N 3.44Å; W296-A300 WeakPolarHBondContact O-CB 3.34Å; W296-A300 PolarHBondContact O-N 3.03Å
297	D	68.6	Low	65.2	Low	7 Å²	7	70.4 Å²	70.4	4%	0.037	35%	0.35	C	S	.	.	H	α-helix	trans	-59.1	-52.6	175.2	-57.9	10.4	0	0	0	110.8	Y181 F283 K293 Q299 A300 L301	Y181-D297 HydrophobicContact CD1-CB 3.65Å; Y181-D297 HydrophobicContact CE1-CB 3.64Å; Y181-D297 WeakPolarHBondContact CE1-OD2 3.41Å; F283-D297 HydrophobicContact CE1-CB 4.33Å; F283-D297 HydrophobicContact CE2-CB 4.39Å; F283-D297 WeakPolarHBondContact CE2-OD1 3.43Å; F283-D297 HydrophobicContact CZ-CB 3.8Å; F283-D297 WeakPolarHBondContact CZ-OD1 3.2Å; K293-D297 VanDerWaalsContact C-CG 3.5Å; K293-D297 VanDerWaalsContact O-CG 3.22Å; K293-D297 PolarHBondContact O-N 3.27Å; D297-Q299 VanDerWaalsContact C-N 3.31Å; D297-Q299 PolarHBondContact O-N 3.29Å; D297-A300 PolarHBondContact O-N 2.96Å; D297-L301 VanDerWaalsContact O-CG 3.3Å; D297-L301 WeakPolarHBondContact O-CG 3.27Å; D297-L301 PolarHBondContact O-N 2.9Å
298	L	70.1	Confident	65.6	Low	15 Å²	15	66.1 Å²	66.1	8%	0.079	33%	0.329	C	S	.	.	H	α-helix	trans	-63.2	-39.3	178.8	-167.9	80.3	0	0	0	111.5	W186 E294 L301 R302	W186-L298 HydrophobicContact CB-CD1 3.88Å; W186-L298 HydrophobicContact CD2-CD1 4.39Å; W186-L298 HydrophobicContact CG-CD1 3.7Å; E294-L298 PolarHBondContact O-N 3.05Å; L298-L301 PolarHBondContact O-N 2.96Å; L298-R302 VanDerWaalsContact CD2-CZ 3.46Å; L298-R302 WeakPolarHBondContact O-CB 3.5Å; L298-R302 VanDerWaalsContact O-CG 3.26Å; L298-R302 WeakPolarHBondContact O-CG 3.37Å; L298-R302 PolarHBondContact O-N 3.27Å
299	Q	72.1	Confident	66.4	Low	78 Å²	78	62.9 Å²	62.9	36%	0.364	32%	0.315	S	S	.	.	H	α-helix	trans	-67.7	-41.2	-180	-169.3	65.6	9.9	0	0	111.6	K295 W296 D297 R302 F303	K295-Q299 WeakPolarHBondContact O-CB 3.27Å; K295-Q299 PolarHBondContact O-N 3.14Å; W296-Q299 PolarHBondContact O-N 3.44Å; D297-Q299 VanDerWaalsContact C-N 3.31Å; D297-Q299 PolarHBondContact O-N 3.29Å; Q299-R302 WeakPolarHBondContact O-CB 3.5Å; Q299-R302 PolarHBondContact O-N 2.91Å; Q299-F303 HydrophobicContact CG-CD2 3.99Å; Q299-F303 HydrophobicContact CG-CE2 3.73Å; Q299-F303 WeakPolarHBondContact O-CD2 3.18Å; Q299-F303 PolarHBondContact O-N 3.34Å
300	A	73.8	Confident	67.1	Low	7 Å²	7	60.4 Å²	60.4	6%	0.058	30%	0.297	C	S	.	.	H	α-helix	trans	-63.6	-41.1	175.5	0	0	0	0	0	111.9	F283 W296 D297 F303 L304	F283-A300 HydrophobicContact CB-CB 4.21Å; F283-A300 HydrophobicContact CD1-CB 4.21Å; F283-A300 HydrophobicContact CG-CB 4.2Å; W296-A300 WeakPolarHBondContact O-CB 3.34Å; W296-A300 PolarHBondContact O-N 3.03Å; D297-A300 PolarHBondContact O-N 2.96Å; A300-F303 PolarHBondContact O-N 3.48Å; A300-L304 PolarHBondContact O-N 2.92Å
301	L	73.7	Confident	67.9	Low	2 Å²	2	55.6 Å²	55.6	1%	0.01	26%	0.263	C	S	.	.	H	α-helix	trans	-64.4	-40.4	173.9	-69.4	171.2	0	0	0	112.1	M116 Y181 W186 F188 F280 D297 L298 L304 S305	M116-L301 HydrophobicContact SD-CD2 4.15Å; Y181-L301 HydrophobicContact CD2-CD1 4.13Å; Y181-L301 HydrophobicContact CE2-CD1 4.38Å; Y181-L301 HydrophobicContact CG-CD1 4.28Å; W186-L301 HydrophobicContact CE3-CB 4.36Å; F188-L301 HydrophobicContact CB-CD1 3.84Å; F188-L301 HydrophobicContact CB-CD2 3.98Å; F188-L301 HydrophobicContact CD1-CD2 3.56Å; F188-L301 HydrophobicContact CD2-CD2 3.72Å; F188-L301 HydrophobicContact CE1-CD2 3.92Å; F188-L301 HydrophobicContact CE2-CD2 4.04Å; F188-L301 HydrophobicContact CG-CD1 4.25Å; F188-L301 HydrophobicContact CG-CD2 3.44Å; F188-L301 VanDerWaalsContact CG-CD2 3.44Å; F188-L301 HydrophobicContact CZ-CD2 4.13Å; F280-L301 HydrophobicContact CD2-CD2 4.22Å; F280-L301 HydrophobicContact CE2-CD2 3.85Å; D297-L301 VanDerWaalsContact O-CG 3.3Å; D297-L301 WeakPolarHBondContact O-CG 3.27Å; D297-L301 PolarHBondContact O-N 2.9Å; L298-L301 PolarHBondContact O-N 2.96Å; L301-L304 PolarHBondContact O-N 3.45Å; L301-S305 PolarHBondContact O-N 3Å; L301-S305 PolarHBondContact O-OG 3.44Å
302	R	79.1	Confident	68.8	Low	41 Å²	41	50 Å²	50	16%	0.155	22%	0.223	C	C	.	.	H	α-helix	trans	-60.8	-47.1	173.4	-76.2	170.4	175.8	177.3	-2.3	111	W186 L298 Q299 L304 S305 I306	W186-R302 HydrophobicContact CH2-CG 4.35Å; W186-R302 HydrophobicContact CZ2-CG 4.17Å; L298-R302 VanDerWaalsContact CD2-CZ 3.46Å; L298-R302 WeakPolarHBondContact O-CB 3.5Å; L298-R302 VanDerWaalsContact O-CG 3.26Å; L298-R302 WeakPolarHBondContact O-CG 3.37Å; L298-R302 PolarHBondContact O-N 3.27Å; Q299-R302 WeakPolarHBondContact O-CB 3.5Å; Q299-R302 PolarHBondContact O-N 2.91Å; R302-L304 VanDerWaalsContact C-N 3.32Å; R302-L304 PolarHBondContact O-N 2.96Å; R302-S305 WeakPolarHBondContact CA-OG 3.46Å; R302-S305 PolarHBondContact O-N 3.42Å; R302-S305 VanDerWaalsContact O-N 3.15Å; R302-S305 PolarHBondContact O-OG 3.26Å; R302-I306 WeakPolarHBondContact O-CB 3.18Å; R302-I306 WeakPolarHBondContact O-CG1 3.16Å; R302-I306 PolarHBondContact O-N 2.96Å
303	F	75.6	Confident	69.6	Low	72 Å²	72	45.9 Å²	45.9	32%	0.316	21%	0.208	S	C	.	.	H	α-helix	trans	-58.6	-42.5	175.3	-83.7	-67.5	0	0	0	112.7	C276 Q299 A300 S305 I306 N307	C276-F303 CarbonylContact O-C 3.58Å; Q299-F303 HydrophobicContact CG-CD2 3.99Å; Q299-F303 HydrophobicContact CG-CE2 3.73Å; Q299-F303 WeakPolarHBondContact O-CD2 3.18Å; Q299-F303 PolarHBondContact O-N 3.34Å; A300-F303 PolarHBondContact O-N 3.48Å; F303-S305 VanDerWaalsContact C-N 3.33Å; F303-S305 PolarHBondContact O-N 2.88Å; F303-I306 PolarHBondContact O-N 2.84Å; F303-N307 PolarHBondContact O-N 2.9Å
304	L	76.2	Confident	70	Confident	5 Å²	5	44.2 Å²	44.2	3%	0.026	20%	0.202	C	C	.	.	H	α-helix	trans	-61.4	-41.8	175.8	-170.6	65.9	0	0	0	111.7	M124 F280 A300 L301 R302 N307	M124-L304 HydrophobicContact CE-CD1 3.67Å; F280-L304 HydrophobicContact CB-CB 4.39Å; F280-L304 HydrophobicContact CB-CD1 4.46Å; F280-L304 HydrophobicContact CD1-CD2 4.15Å; F280-L304 HydrophobicContact CD2-CD2 4Å; F280-L304 HydrophobicContact CE1-CD2 4.36Å; F280-L304 HydrophobicContact CE2-CD2 4.2Å; F280-L304 HydrophobicContact CG-CD1 4.5Å; F280-L304 HydrophobicContact CG-CD2 3.98Å; F280-L304 HydrophobicContact CZ-CD2 4.39Å; A300-L304 PolarHBondContact O-N 2.92Å; L301-L304 PolarHBondContact O-N 3.45Å; R302-L304 VanDerWaalsContact C-N 3.32Å; R302-L304 PolarHBondContact O-N 2.96Å; L304-N307 VanDerWaalsContact O-CB 3.25Å; L304-N307 WeakPolarHBondContact O-CB 3.42Å; L304-N307 PolarHBondContact O-N 2.94Å
305	S	71.4	Confident	70.3	Confident	28 Å²	28	40.2 Å²	40.2	20%	0.196	18%	0.183	C	C	.	.	H	α-helix	trans	-72.2	-27.5	177.3	70.5	0	0	0	0	114.1	M31 W186 L301 R302 F303 N307	M31-S305 VanDerWaalsContact CE-OG 3.29Å; M31-S305 WeakPolarHBondContact CE-OG 3.24Å; W186-S305 WeakPolarHBondContact CH2-OG 3.08Å; L301-S305 PolarHBondContact O-N 3Å; L301-S305 PolarHBondContact O-OG 3.44Å; R302-S305 WeakPolarHBondContact CA-OG 3.46Å; R302-S305 PolarHBondContact O-N 3.42Å; R302-S305 VanDerWaalsContact O-N 3.15Å; R302-S305 PolarHBondContact O-OG 3.26Å; F303-S305 VanDerWaalsContact C-N 3.33Å; F303-S305 PolarHBondContact O-N 2.88Å; S305-N307 PolarHBondContact O-N 3.29Å
306	I	74.3	Confident	70.2	Confident	41 Å²	41	32.4 Å²	32.4	21%	0.21	15%	0.152	C	C	.	.	H	α-helix	trans	-66.9	-23.4	176.3	-75.9	165.9	0	0	0	110.9	M31 R302 F303 S308 I309 I310	M31-I306 HydrophobicContact CE-CG1 3.86Å; R302-I306 WeakPolarHBondContact O-CB 3.18Å; R302-I306 WeakPolarHBondContact O-CG1 3.16Å; R302-I306 PolarHBondContact O-N 2.96Å; F303-I306 PolarHBondContact O-N 2.84Å; I306-S308 PolarHBondContact O-N 2.9Å; I306-I309 WeakPolarHBondContact O-CA 3.49Å; I306-I309 WeakPolarHBondContact O-CB 3.2Å; I306-I309 PolarHBondContact O-N 2.91Å; I306-I310 HydrophobicContact CG2-CD1 3.29Å; I306-I310 HydrophobicContact CG2-CG1 3.6Å; I306-I310 PolarHBondContact O-N 3.23Å
307	N	72.3	Confident	69.9	Low	3 Å²	3	29 Å²	29	2%	0.016	15%	0.145	C	C	.	.	H	α-helix	trans	-53.3	-51.5	177.4	-167.3	67.5	0	0	0	111.9	F273 C276 F303 L304 S305 I309 I310 D311	F273-N307 WeakPolarHBondContact CA-OD1 3.37Å; C276-N307 HydrophobicContact CB-CB 3.9Å; F303-N307 PolarHBondContact O-N 2.9Å; L304-N307 VanDerWaalsContact O-CB 3.25Å; L304-N307 WeakPolarHBondContact O-CB 3.42Å; L304-N307 PolarHBondContact O-N 2.94Å; S305-N307 PolarHBondContact O-N 3.29Å; N307-I309 PolarHBondContact O-N 2.66Å; N307-I309 VanDerWaalsContact O-N 3.14Å; N307-I310 PolarHBondContact O-N 3.41Å; N307-D311 PolarHBondContact ND2-OD2 3.49Å; N307-D311 WeakPolarHBondContact O-CB 3.25Å; N307-D311 PolarHBondContact O-N 3.31Å; N307-D311 VanDerWaalsContact O-N 3.09Å
308	S	69.4	Low	69.2	Low	20 Å²	20	30.2 Å²	30.2	14%	0.14	15%	0.151	C	C	.	.	H	α-helix	trans	-67	-12.5	177.1	-67.5	0	0	0	0	114.6	D78 I306 P312	D78-S308 VanDerWaalsContact OD1-CB 3.23Å; D78-S308 WeakPolarHBondContact OD1-CB 3.29Å; D78-S308 PolarHBondContact OD1-OG 2.97Å; I306-S308 PolarHBondContact O-N 2.9Å; S308-P312 WeakPolarHBondContact O-CD 3.21Å
309	I	70.4	Confident	68.7	Low	21 Å²	21	31.5 Å²	31.5	11%	0.108	16%	0.155	C	C	.	.	H	α-helix	trans	-89.5	-45.9	174.7	-61	171.3	0	0	0	109.6	M31 A34 I306 N307 P312	M31-I309 HydrophobicContact CB-CD1 3.74Å; M31-I309 HydrophobicContact CE-CD1 3.94Å; M31-I309 HydrophobicContact CG-CD1 4.08Å; M31-I309 WeakPolarHBondContact O-CD1 3.34Å; A34-I309 HydrophobicContact CB-CG2 4.1Å; I306-I309 WeakPolarHBondContact O-CA 3.49Å; I306-I309 WeakPolarHBondContact O-CB 3.2Å; I306-I309 PolarHBondContact O-N 2.91Å; N307-I309 PolarHBondContact O-N 2.66Å; N307-I309 VanDerWaalsContact O-N 3.14Å; I309-P312 WeakPolarHBondContact O-CD 3.41Å
310	I	69.3	Low	67.8	Low	58 Å²	58	28.4 Å²	28.4	30%	0.297	14%	0.142	S	C	.	.	H	α-helix	trans	-74.9	-33.7	-174.1	-59.7	179.8	0	0	0	111.7	T272 I306 N307 W313 V314	T272-I310 HydrophobicContact CG2-CB 3.83Å; T272-I310 HydrophobicContact CG2-CG2 3.36Å; I306-I310 HydrophobicContact CG2-CD1 3.29Å; I306-I310 HydrophobicContact CG2-CG1 3.6Å; I306-I310 PolarHBondContact O-N 3.23Å; N307-I310 PolarHBondContact O-N 3.41Å; I310-W313 PolarHBondContact O-N 3.19Å; I310-V314 HydrophobicContact CG2-CG2 3.69Å; I310-V314 WeakPolarHBondContact O-CG2 3.41Å; I310-V314 PolarHBondContact O-N 3.19Å
311	D	70.6	Confident	66.6	Low	1 Å²	1	31.1 Å²	31.1	1%	0.005	16%	0.159	C	C	.	.	H	α-helix	trans	-53.5	-47.9	-176.6	-73.2	-21.8	0	0	0	113.2	N307 V314 F315	N307-D311 PolarHBondContact ND2-OD2 3.49Å; N307-D311 WeakPolarHBondContact O-CB 3.25Å; N307-D311 PolarHBondContact O-N 3.31Å; N307-D311 VanDerWaalsContact O-N 3.09Å; D311-V314 PolarHBondContact O-N 3.38Å; D311-F315 PolarHBondContact O-N 3.17Å
312	P	66.6	Low	65.4	Low	0 Å²	0	33.5 Å²	33.5	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-65.9	-36.1	173.8	-20.7	30	0	0	0	114.5	N39 A42 S308 I309 F315 A316	N39-P312 HydrophobicContact CB-CG 4.45Å; N39-P312 VanDerWaalsContact CG-CG 3.42Å; N39-P312 WeakPolarHBondContact OD1-CG 3.31Å; A42-P312 HydrophobicContact CB-CB 4.13Å; S308-P312 WeakPolarHBondContact O-CD 3.21Å; I309-P312 WeakPolarHBondContact O-CD 3.41Å; P312-F315 PolarHBondContact O-N 3.29Å; P312-A316 VanDerWaalsContact O-CB 3.28Å; P312-A316 WeakPolarHBondContact O-CB 3.46Å; P312-A316 PolarHBondContact O-N 2.96Å
313	W	67	Low	64.1	Low	74 Å²	74	32.3 Å²	32.3	28%	0.28	17%	0.17	S	C	.	.	H	α-helix	trans	-68.2	-40.3	177.2	-73.4	110.9	0	0	0	111.1	A34 L37 I41 I310 F315 A316 I317	A34-W313 PolarHBondContact O-NE1 3.04Å; L37-W313 HydrophobicContact CB-CZ2 4.42Å; L37-W313 HydrophobicContact CD2-CH2 4.16Å; L37-W313 HydrophobicContact CD2-CZ2 4.41Å; L37-W313 HydrophobicContact CG-CH2 4.28Å; L37-W313 HydrophobicContact CG-CZ2 4.39Å; I41-W313 HydrophobicContact CD1-CH2 4.28Å; I41-W313 HydrophobicContact CD1-CZ3 4.46Å; I310-W313 PolarHBondContact O-N 3.19Å; W313-F315 VanDerWaalsContact C-N 3.29Å; W313-F315 PolarHBondContact O-N 2.56Å; W313-A316 PolarHBondContact O-N 3.23Å; W313-I317 HydrophobicContact CB-CD1 4.26Å; W313-I317 HydrophobicContact CE3-CD1 3.94Å; W313-I317 HydrophobicContact CE3-CG1 4.34Å; W313-I317 WeakPolarHBondContact O-CB 3.45Å; W313-I317 VanDerWaalsContact O-CG1 3.23Å; W313-I317 WeakPolarHBondContact O-CG1 3.29Å; W313-I317 PolarHBondContact O-N 2.99Å
314	V	68.3	Low	63.1	Low	13 Å²	13	34.4 Å²	34.4	8%	0.079	18%	0.176	C	C	.	.	H	α-helix	trans	-58.8	-44.6	171.3	166.5	0	0	0	0	109.6	L265 I268 M269 T272 I310 D311 L318	L265-V314 HydrophobicContact CD1-CG1 4.17Å; I268-V314 HydrophobicContact CB-CG1 4.4Å; I268-V314 HydrophobicContact CG2-CG1 3.88Å; I268-V314 HydrophobicContact CG2-CG2 4.5Å; M269-V314 HydrophobicContact CG-CG1 3.7Å; T272-V314 HydrophobicContact CG2-CG2 4.49Å; I310-V314 HydrophobicContact CG2-CG2 3.69Å; I310-V314 WeakPolarHBondContact O-CG2 3.41Å; I310-V314 PolarHBondContact O-N 3.19Å; D311-V314 PolarHBondContact O-N 3.38Å; V314-L318 HydrophobicContact CB-CD1 4.36Å; V314-L318 HydrophobicContact CG1-CD1 3.87Å; V314-L318 HydrophobicContact CG2-CD1 4.42Å; V314-L318 WeakPolarHBondContact O-CA 3.49Å; V314-L318 WeakPolarHBondContact O-CB 3.43Å; V314-L318 PolarHBondContact O-N 3.06Å
315	F	63.6	Low	61.9	Low	10 Å²	10	39.3 Å²	39.3	4%	0.044	20%	0.202	C	C	.	.	H	α-helix	trans	-65.1	-42.5	176.5	-171.4	-94.6	0	0	0	114	A42 L46 V71 L265 D311 P312 W313	A42-F315 HydrophobicContact CB-CD1 4.23Å; L46-F315 HydrophobicContact CD1-CE1 4.14Å; L46-F315 HydrophobicContact CD2-CE1 3.7Å; L46-F315 HydrophobicContact CD2-CZ 3.58Å; L46-F315 HydrophobicContact CG-CE1 3.75Å; L46-F315 HydrophobicContact CG-CZ 4.17Å; V71-F315 HydrophobicContact CG1-CD2 3.7Å; V71-F315 HydrophobicContact CG1-CE1 4.39Å; V71-F315 HydrophobicContact CG1-CE2 3.49Å; V71-F315 VanDerWaalsContact CG1-CE2 3.49Å; V71-F315 HydrophobicContact CG1-CG 4.29Å; V71-F315 HydrophobicContact CG1-CZ 3.87Å; L265-F315 HydrophobicContact CD1-CD2 4.46Å; L265-F315 HydrophobicContact CD2-CD2 3.7Å; L265-F315 HydrophobicContact CD2-CE2 3.74Å; D311-F315 PolarHBondContact O-N 3.17Å; P312-F315 PolarHBondContact O-N 3.29Å; W313-F315 VanDerWaalsContact C-N 3.29Å; W313-F315 PolarHBondContact O-N 2.56Å
316	A	59.1	Low	61	Low	15 Å²	15	42.3 Å²	42.3	12%	0.124	21%	0.214	C	C	.	.	H	α-helix	trans	-72.3	-43.7	-177.6	0	0	0	0	0	112.3	I41 L45 P312 W313	I41-A316 HydrophobicContact CG2-CB 4.11Å; L45-A316 HydrophobicContact CD1-CB 4.14Å; P312-A316 VanDerWaalsContact O-CB 3.28Å; P312-A316 WeakPolarHBondContact O-CB 3.46Å; P312-A316 PolarHBondContact O-N 2.96Å; W313-A316 PolarHBondContact O-N 3.23Å
317	I	56.9	Low	60.2	Low	97 Å²	97	46.3 Å²	46.3	50%	0.497	23%	0.226	S	C	.	.	H	α-helix	trans	-82.1	-42	-175.3	-61.1	170.7	0	0	0	111.1	W313 R319 V322	W313-I317 HydrophobicContact CB-CD1 4.26Å; W313-I317 HydrophobicContact CE3-CD1 3.94Å; W313-I317 HydrophobicContact CE3-CG1 4.34Å; W313-I317 WeakPolarHBondContact O-CB 3.45Å; W313-I317 VanDerWaalsContact O-CG1 3.23Å; W313-I317 WeakPolarHBondContact O-CG1 3.29Å; W313-I317 PolarHBondContact O-N 2.99Å; I317-R319 VanDerWaalsContact C-N 3.28Å; I317-R319 PolarHBondContact O-N 3.44Å; I317-V322 WeakPolarHBondContact O-CB 3.26Å; I317-V322 VanDerWaalsContact O-CG1 3.29Å; I317-V322 WeakPolarHBondContact O-CG1 3.45Å
318	L	53.4	Low	59.4	Low	33 Å²	33	48.9 Å²	48.9	17%	0.173	24%	0.244	C	C	.	.	S	Bend	trans	-96.9	36.4	-175.2	-61.2	153.2	0	0	0	112.4	L265 I268 V314 L323 M326	L265-L318 HydrophobicContact CD1-CB 4.33Å; I268-L318 HydrophobicContact CB-CD1 4.29Å; I268-L318 HydrophobicContact CD1-CD1 3.79Å; I268-L318 HydrophobicContact CD1-CD2 4.02Å; I268-L318 HydrophobicContact CD1-CG 4.34Å; I268-L318 HydrophobicContact CG2-CD1 3.57Å; V314-L318 HydrophobicContact CB-CD1 4.36Å; V314-L318 HydrophobicContact CG1-CD1 3.87Å; V314-L318 HydrophobicContact CG2-CD1 4.42Å; V314-L318 WeakPolarHBondContact O-CA 3.49Å; V314-L318 WeakPolarHBondContact O-CB 3.43Å; V314-L318 PolarHBondContact O-N 3.06Å; L318-L323 HydrophobicContact CB-CD1 4.45Å; L318-L323 HydrophobicContact CB-CD2 4.37Å; L318-L323 HydrophobicContact CB-CG 4.4Å; L318-L323 HydrophobicContact CD2-CD2 3.79Å; L318-L323 WeakPolarHBondContact O-CD1 3.48Å; L318-L323 WeakPolarHBondContact O-CG 3.17Å; L318-M326 HydrophobicContact CD2-CE 3.95Å
319	R	59.8	Low	58.8	Low	43 Å²	43	51.4 Å²	51.4	16%	0.162	26%	0.259	C	S	.	.			trans	-57.8	141.6	176.4	-117.6	175.9	178.6	-141.9	-11.6	110.8	L45 I317 P321 V322 L323	L45-R319 PolarHBondContact O-NH2 3.35Å; I317-R319 VanDerWaalsContact C-N 3.28Å; I317-R319 PolarHBondContact O-N 3.44Å; R319-P321 VanDerWaalsContact C-CD 3.47Å; R319-P321 VanDerWaalsContact C-N 3.32Å; R319-P321 HydrophobicContact CB-CG 4.1Å; R319-P321 VanDerWaalsContact O-N 3.14Å; R319-V322 HydrophobicContact CB-CB 4.33Å; R319-V322 HydrophobicContact CB-CG2 3.93Å; R319-V322 CarbonylContact O-C 3.19Å; R319-V322 WeakPolarHBondContact O-CA 3.31Å; R319-V322 WeakPolarHBondContact O-CB 3.3Å; R319-V322 PolarHBondContact O-N 3.38Å; R319-L323 PolarHBondContact O-N 2.83Å
320	P	52.3	Low	58.2	Low	12 Å²	12	55.4 Å²	55.4	8%	0.078	28%	0.28	C	S	.	.	H	α-helix	trans	-40.6	-47.2	170.8	-34.6	38.5	0	0	0	115.7	D261 V322 L323 R324	D261-P320 HydrophobicContact CB-CB 3.47Å; D261-P320 VanDerWaalsContact CB-CB 3.47Å; D261-P320 HydrophobicContact CB-CG 3.84Å; P320-V322 PolarHBondContact O-N 3.01Å; P320-L323 PolarHBondContact O-N 3.11Å; P320-R324 WeakPolarHBondContact O-CB 3.23Å; P320-R324 VanDerWaalsContact O-CG 3.25Å; P320-R324 WeakPolarHBondContact O-CG 3.23Å; P320-R324 PolarHBondContact O-N 3.16Å
321	P	49.5	Very low	57.6	Low	64 Å²	64	56.4 Å²	56.4	42%	0.416	29%	0.291	S	S	.	.	H	α-helix	trans	-65.8	-33.2	174.3	23.6	-33.4	0	0	0	114.2	R319 L325	R319-P321 VanDerWaalsContact C-CD 3.47Å; R319-P321 VanDerWaalsContact C-N 3.32Å; R319-P321 HydrophobicContact CB-CG 4.1Å; R319-P321 VanDerWaalsContact O-N 3.14Å; P321-L325 VanDerWaalsContact O-CB 3.3Å; P321-L325 WeakPolarHBondContact O-CB 3.49Å; P321-L325 PolarHBondContact O-N 3.45Å
322	V	47.7	Very low	56.7	Low	53 Å²	53	60 Å²	60	32%	0.321	32%	0.315	S	S	.	.	H	α-helix	trans	-73.9	-39.8	175.8	-176.3	0	0	0	0	110.6	I317 R319 P320 L325 M326	I317-V322 WeakPolarHBondContact O-CB 3.26Å; I317-V322 VanDerWaalsContact O-CG1 3.29Å; I317-V322 WeakPolarHBondContact O-CG1 3.45Å; R319-V322 HydrophobicContact CB-CB 4.33Å; R319-V322 HydrophobicContact CB-CG2 3.93Å; R319-V322 CarbonylContact O-C 3.19Å; R319-V322 WeakPolarHBondContact O-CA 3.31Å; R319-V322 WeakPolarHBondContact O-CB 3.3Å; R319-V322 PolarHBondContact O-N 3.38Å; P320-V322 PolarHBondContact O-N 3.01Å; V322-L325 CarbonylContact O-C 3.59Å; V322-L325 PolarHBondContact O-N 3.06Å; V322-M326 HydrophobicContact CG1-CE 4.39Å; V322-M326 HydrophobicContact CG1-CG 4.36Å; V322-M326 WeakPolarHBondContact O-CB 3.33Å; V322-M326 VanDerWaalsContact O-CG 3.31Å; V322-M326 WeakPolarHBondContact O-CG 3.23Å; V322-M326 PolarHBondContact O-N 2.68Å
323	L	52.8	Low	55.8	Low	16 Å²	16	68.7 Å²	68.7	8%	0.084	35%	0.348	C	S	.	.	H	α-helix	trans	-64.4	-39.7	172.4	-72.8	172.8	0	0	0	111.9	I264 L318 R319 P320 M326 R327	I264-L323 HydrophobicContact CB-CD1 4.21Å; I264-L323 HydrophobicContact CG2-CD1 3.82Å; I264-L323 HydrophobicContact CG2-CD2 4.35Å; L318-L323 HydrophobicContact CB-CD1 4.45Å; L318-L323 HydrophobicContact CB-CD2 4.37Å; L318-L323 HydrophobicContact CB-CG 4.4Å; L318-L323 HydrophobicContact CD2-CD2 3.79Å; L318-L323 WeakPolarHBondContact O-CD1 3.48Å; L318-L323 WeakPolarHBondContact O-CG 3.17Å; R319-L323 PolarHBondContact O-N 2.83Å; P320-L323 PolarHBondContact O-N 3.11Å; L323-M326 HydrophobicContact CD2-CE 3.72Å; L323-M326 PolarHBondContact O-N 2.96Å; L323-R327 VanDerWaalsContact O-CB 3.25Å; L323-R327 WeakPolarHBondContact O-CB 3.32Å; L323-R327 WeakPolarHBondContact O-CG 3.37Å; L323-R327 PolarHBondContact O-N 2.96Å
324	R	54.5	Low	54.7	Low	115 Å²	115	69.6 Å²	69.6	43%	0.434	36%	0.357	S	S	.	.	H	α-helix	trans	-64.4	-40.1	172.7	-75.7	-173	-64.1	-170.6	2	111.6	D261 P320 S328	D261-R324 WeakPolarHBondContact OD2-CD 3.42Å; D261-R324 WeakPolarHBondContact OD2-CG 3.28Å; D261-R324 IonicContact OD2-NE 2.73Å; P320-R324 WeakPolarHBondContact O-CB 3.23Å; P320-R324 VanDerWaalsContact O-CG 3.25Å; P320-R324 WeakPolarHBondContact O-CG 3.23Å; P320-R324 PolarHBondContact O-N 3.16Å; R324-S328 WeakPolarHBondContact O-CB 3.37Å; R324-S328 PolarHBondContact O-N 3.43Å; R324-S328 PolarHBondContact O-OG 2.98Å
325	L	51.2	Low	53.4	Low	109 Å²	109	72.3 Å²	72.3	57%	0.571	38%	0.377	S	S	*	.	H	α-helix	trans	-67.8	-45.2	174.8	-175.2	67.5	0	0	0	111.8	P321 V322 R327 S328 V329	P321-L325 VanDerWaalsContact O-CB 3.3Å; P321-L325 WeakPolarHBondContact O-CB 3.49Å; P321-L325 PolarHBondContact O-N 3.45Å; V322-L325 CarbonylContact O-C 3.59Å; V322-L325 PolarHBondContact O-N 3.06Å; L325-R327 PolarHBondContact O-N 2.73Å; L325-S328 PolarHBondContact O-N 2.91Å; L325-S328 PolarHBondContact O-OG 2.85Å; L325-V329 WeakPolarHBondContact O-CB 3.44Å; L325-V329 VanDerWaalsContact O-CG2 3.22Å; L325-V329 WeakPolarHBondContact O-CG2 3.13Å; L325-V329 PolarHBondContact O-N 3.48Å
326	M	52.9	Low	52.4	Low	91 Å²	91	76.5 Å²	76.5	45%	0.448	40%	0.399	S	S	.	.	H	α-helix	trans	-64.2	-41.3	176.4	-74.7	-162.9	-60.6	0	0	111.3	L318 V322 L323 V329 L330	L318-M326 HydrophobicContact CD2-CE 3.95Å; V322-M326 HydrophobicContact CG1-CE 4.39Å; V322-M326 HydrophobicContact CG1-CG 4.36Å; V322-M326 WeakPolarHBondContact O-CB 3.33Å; V322-M326 VanDerWaalsContact O-CG 3.31Å; V322-M326 WeakPolarHBondContact O-CG 3.23Å; V322-M326 PolarHBondContact O-N 2.68Å; L323-M326 HydrophobicContact CD2-CE 3.72Å; L323-M326 PolarHBondContact O-N 2.96Å; M326-V329 PolarHBondContact O-N 2.93Å; M326-L330 WeakPolarHBondContact O-CB 3.33Å; M326-L330 PolarHBondContact O-N 2.93Å
327	R	57	Low	51.3	Low	124 Å²	124	85.1 Å²	85.1	47%	0.468	43%	0.429	S	S	.	.	H	α-helix	trans	-65.6	-40.8	172	-85.8	-178.6	169	165.4	-4.3	112.3	D261 L323 L325 V329 L330 C331	D261-R327 IonicContact OD1-NH1 3Å; L323-R327 VanDerWaalsContact O-CB 3.25Å; L323-R327 WeakPolarHBondContact O-CB 3.32Å; L323-R327 WeakPolarHBondContact O-CG 3.37Å; L323-R327 PolarHBondContact O-N 2.96Å; L325-R327 PolarHBondContact O-N 2.73Å; R327-V329 VanDerWaalsContact C-N 3.34Å; R327-L330 PolarHBondContact O-N 2.87Å; R327-C331 WeakPolarHBondContact O-CA 3.4Å; R327-C331 WeakPolarHBondContact O-CB 3.22Å; R327-C331 PolarHBondContact O-N 3.34Å; R327-C331 PolarHBondContact O-SG 3.03Å
328	S	55.4	Low	50.4	Low	57 Å²	57	84 Å²	84	40%	0.399	43%	0.426	S	S	.	.	H	α-helix	trans	-65.6	-41.6	177.6	72.6	0	0	0	0	110.5	R324 L325 C332	R324-S328 WeakPolarHBondContact O-CB 3.37Å; R324-S328 PolarHBondContact O-N 3.43Å; R324-S328 PolarHBondContact O-OG 2.98Å; L325-S328 PolarHBondContact O-N 2.91Å; L325-S328 PolarHBondContact O-OG 2.85Å; S328-C332 WeakPolarHBondContact O-CB 3Å; S328-C332 PolarHBondContact O-N 3.39Å; S328-C332 PolarHBondContact O-SG 3.45Å
329	V	57.1	Low	50	Low	74 Å²	74	88.1 Å²	88.1	45%	0.448	45%	0.445	S	S	.	.	H	α-helix	trans	-64.2	-46.5	174.8	172.6	0	0	0	0	110.7	L325 M326 R327 C332 R333	L325-V329 WeakPolarHBondContact O-CB 3.44Å; L325-V329 VanDerWaalsContact O-CG2 3.22Å; L325-V329 WeakPolarHBondContact O-CG2 3.13Å; L325-V329 PolarHBondContact O-N 3.48Å; M326-V329 PolarHBondContact O-N 2.93Å; R327-V329 VanDerWaalsContact C-N 3.34Å; V329-C332 PolarHBondContact O-N 2.99Å; V329-R333 WeakPolarHBondContact O-CB 3.39Å; V329-R333 VanDerWaalsContact O-CG 3.25Å; V329-R333 WeakPolarHBondContact O-CG 3.4Å; V329-R333 PolarHBondContact O-N 3.45Å
330	L	57.7	Low	49.2	Very low	105 Å²	105	90.6 Å²	90.6	55%	0.55	46%	0.461	S	S	.	.	H	α-helix	trans	-67.6	-39.9	179.5	-170	65.4	0	0	0	112.1	M326 R327 R333 I334	M326-L330 WeakPolarHBondContact O-CB 3.33Å; M326-L330 PolarHBondContact O-N 2.93Å; R327-L330 PolarHBondContact O-N 2.87Å; L330-R333 PolarHBondContact O-N 2.02Å; L330-I334 HydrophobicContact CG-CD1 4Å; L330-I334 WeakPolarHBondContact O-CB 3.49Å; L330-I334 WeakPolarHBondContact O-CD1 3.49Å; L330-I334 WeakPolarHBondContact O-CG1 3.38Å; L330-I334 PolarHBondContact O-N 3.15Å
331	C	56	Low	48.7	Very low	78 Å²	78	94.2 Å²	94.2	53%	0.527	48%	0.483	S	S	.	.	H	α-helix	trans	-69.2	-36.3	173.6	-75.4	0	0	0	0	112	R327 R333 I334 S335	R327-C331 WeakPolarHBondContact O-CA 3.4Å; R327-C331 WeakPolarHBondContact O-CB 3.22Å; R327-C331 PolarHBondContact O-N 3.34Å; R327-C331 PolarHBondContact O-SG 3.03Å; C331-R333 VanDerWaalsContact C-N 3.34Å; C331-I334 PolarHBondContact O-N 3.1Å; C331-S335 WeakPolarHBondContact O-CB 3.32Å; C331-S335 PolarHBondContact O-N 3.16Å
332	C	51.3	Low	48.3	Very low	76 Å²	76	96.1 Å²	96.1	51%	0.514	49%	0.489	S	S	.	.	H	α-helix	trans	-64.5	-40.2	170.4	-75.1	0	0	0	0	110.6	S328 V329 S335 L336	S328-C332 WeakPolarHBondContact O-CB 3Å; S328-C332 PolarHBondContact O-N 3.39Å; S328-C332 PolarHBondContact O-SG 3.45Å; V329-C332 PolarHBondContact O-N 2.99Å; C332-S335 PolarHBondContact O-N 3.3Å; C332-L336 VanDerWaalsContact O-CB 3.27Å; C332-L336 WeakPolarHBondContact O-CB 3.17Å; C332-L336 WeakPolarHBondContact O-CD1 3.45Å; C332-L336 WeakPolarHBondContact O-CG 3.26Å; C332-L336 PolarHBondContact O-N 3.45Å
333	R	49	Very low	48.1	Very low	184 Å²	184	100.1 Å²	100.1	69%	0.694	50%	0.504	S	S	*	.	H	α-helix	trans	-68.3	-35.7	174.8	-68.6	-140.2	-177	-159.6	0.8	113.3	V329 L330 C331 R337	V329-R333 WeakPolarHBondContact O-CB 3.39Å; V329-R333 VanDerWaalsContact O-CG 3.25Å; V329-R333 WeakPolarHBondContact O-CG 3.4Å; V329-R333 PolarHBondContact O-N 3.45Å; L330-R333 PolarHBondContact O-N 2.02Å; C331-R333 VanDerWaalsContact C-N 3.34Å; R333-R337 WeakPolarHBondContact O-CB 2.97Å; R333-R337 PolarHBondContact O-N 3.49Å
334	I	44.2	Very low	47.5	Very low	92 Å²	92	103.6 Å²	103.6	47%	0.472	53%	0.526	S	S	.	.	H	α-helix	trans	-72.8	-40	174.8	-69	163.7	0	0	0	110.4	L330 C331 R337 T338	L330-I334 HydrophobicContact CG-CD1 4Å; L330-I334 WeakPolarHBondContact O-CB 3.49Å; L330-I334 WeakPolarHBondContact O-CD1 3.49Å; L330-I334 WeakPolarHBondContact O-CG1 3.38Å; L330-I334 PolarHBondContact O-N 3.15Å; C331-I334 PolarHBondContact O-N 3.1Å; I334-R337 PolarHBondContact O-N 3.05Å; I334-T338 WeakPolarHBondContact O-CB 3.44Å; I334-T338 PolarHBondContact O-N 3.14Å; I334-T338 PolarHBondContact O-OG1 3.34Å
335	S	40.5	Very low	46.7	Very low	70 Å²	70	101.2 Å²	101.2	49%	0.49	53%	0.527	S	S	.	.	H	α-helix	trans	-66.7	-40.8	176.6	-167	0	0	0	0	111.8	C331 C332 T338 Q339	C331-S335 WeakPolarHBondContact O-CB 3.32Å; C331-S335 PolarHBondContact O-N 3.16Å; C332-S335 PolarHBondContact O-N 3.3Å; S335-T338 PolarHBondContact O-N 3.03Å; S335-Q339 WeakPolarHBondContact O-CB 3.21Å; S335-Q339 PolarHBondContact O-N 2.87Å
336	L	41.8	Very low	46.2	Very low	99 Å²	99	100.3 Å²	100.3	52%	0.518	53%	0.529	S	S	.	.	H	α-helix	trans	-63.7	-47.8	172.2	-87.8	151.7	0	0	0	111.1	C332 T338 Q339 D340	C332-L336 VanDerWaalsContact O-CB 3.27Å; C332-L336 WeakPolarHBondContact O-CB 3.17Å; C332-L336 WeakPolarHBondContact O-CD1 3.45Å; C332-L336 WeakPolarHBondContact O-CG 3.26Å; C332-L336 PolarHBondContact O-N 3.45Å; L336-T338 VanDerWaalsContact C-N 3.28Å; L336-T338 PolarHBondContact O-N 3.22Å; L336-Q339 PolarHBondContact O-N 3.14Å; L336-Q339 VanDerWaalsContact O-N 3.15Å; L336-D340 PolarHBondContact O-N 3Å
337	R	37.3	Very low	45.7	Very low	196 Å²	196	99 Å²	99	74%	0.74	53%	0.529	S	S	*	.	H	α-helix	trans	-64	-31.4	178	-167	172.6	-178.1	166.7	1.4	113.1	R333 I334 T341	R333-R337 WeakPolarHBondContact O-CB 2.97Å; R333-R337 PolarHBondContact O-N 3.49Å; I334-R337 PolarHBondContact O-N 3.05Å; R337-T341 PolarHBondContact O-N 3.37Å; R337-T341 PolarHBondContact O-OG1 3.45Å
338	T	38.1	Very low	44.9	Very low	73 Å²	73	98.1 Å²	98.1	45%	0.448	54%	0.537	S	S	.	.	H	α-helix	trans	-76.6	-34	175.9	-47.8	0	0	0	0	111.3	I334 S335 L336 I342	I334-T338 WeakPolarHBondContact O-CB 3.44Å; I334-T338 PolarHBondContact O-N 3.14Å; I334-T338 PolarHBondContact O-OG1 3.34Å; S335-T338 PolarHBondContact O-N 3.03Å; L336-T338 VanDerWaalsContact C-N 3.28Å; L336-T338 PolarHBondContact O-N 3.22Å; T338-I342 HydrophobicContact CG2-CD1 4.04Å; T338-I342 VanDerWaalsContact O-CG1 3.27Å; T338-I342 WeakPolarHBondContact O-CG1 3.41Å; T338-I342 PolarHBondContact O-N 3.36Å; T338-I342 VanDerWaalsContact O-N 3.16Å
339	Q	43.5	Very low	44.2	Very low	120 Å²	120	102.9 Å²	102.9	56%	0.561	55%	0.553	S	S	*	*	H	α-helix	trans	-66.9	-42.9	172.1	-104.6	175.3	-29.5	0	0	112.2	S335 L336 T341 I342 Q343	S335-Q339 WeakPolarHBondContact O-CB 3.21Å; S335-Q339 PolarHBondContact O-N 2.87Å; L336-Q339 PolarHBondContact O-N 3.14Å; L336-Q339 VanDerWaalsContact O-N 3.15Å; Q339-T341 VanDerWaalsContact C-N 3.3Å; Q339-T341 PolarHBondContact O-N 3.3Å; Q339-I342 PolarHBondContact O-N 3.16Å; Q339-Q343 PolarHBondContact O-N 3.33Å
340	D	44.4	Very low	43.3	Very low	94 Å²	94	102.8 Å²	102.8	50%	0.503	56%	0.556	S	S	.	*	H	α-helix	trans	-64.7	-34.6	178	-69.7	-25.2	0	0	0	112.2	L336 T344	L336-D340 PolarHBondContact O-N 3Å; D340-T344 PolarHBondContact O-N 3.22Å; D340-T344 PolarHBondContact O-OG1 3.45Å
341	T	40.8	Very low	42.5	Very low	88 Å²	88	104.2 Å²	104.2	54%	0.54	56%	0.564	S	S	.	*	H	α-helix	trans	-75.6	-31.5	178.7	-44.9	0	0	0	0	112.2	R337 Q339 T344 S345	R337-T341 PolarHBondContact O-N 3.37Å; R337-T341 PolarHBondContact O-OG1 3.45Å; Q339-T341 VanDerWaalsContact C-N 3.3Å; Q339-T341 PolarHBondContact O-N 3.3Å; T341-T344 PolarHBondContact O-OG1 2.98Å; T341-S345 PolarHBondContact O-N 3.07Å; T341-S345 PolarHBondContact O-OG 3.45Å
342	I	41.7	Very low	41.9	Very low	104 Å²	104	104.5 Å²	104.5	53%	0.533	57%	0.572	S	S	.	*	H	α-helix	trans	-78.3	-34.6	176.7	-67	169.7	0	0	0	111.2	T338 Q339 S345 C346	T338-I342 HydrophobicContact CG2-CD1 4.04Å; T338-I342 VanDerWaalsContact O-CG1 3.27Å; T338-I342 WeakPolarHBondContact O-CG1 3.41Å; T338-I342 PolarHBondContact O-N 3.36Å; T338-I342 VanDerWaalsContact O-N 3.16Å; Q339-I342 PolarHBondContact O-N 3.16Å; I342-S345 PolarHBondContact O-OG 3.39Å; I342-C346 PolarHBondContact O-N 3.39Å
343	Q	42.3	Very low	41.5	Very low	138 Å²	138	105.3 Å²	105.3	65%	0.645	58%	0.579	S	S	*	*	H	α-helix	trans	-70.4	-36.4	175.7	-93.4	179.2	-25.1	0	0	113	Q339 C346 S347	Q339-Q343 PolarHBondContact O-N 3.33Å; Q343-C346 PolarHBondContact O-N 2.83Å; Q343-S347 PolarHBondContact O-N 2.98Å; Q343-S347 PolarHBondContact O-OG 3.41Å
344	T	41.5	Very low	41.2	Very low	88 Å²	88	105.5 Å²	105.5	54%	0.54	59%	0.585	S	S	.	*	H	α-helix	trans	-73	-25.2	177.3	38.6	0	0	0	0	113.8	D340 T341 S347 T348	D340-T344 PolarHBondContact O-N 3.22Å; D340-T344 PolarHBondContact O-OG1 3.45Å; T341-T344 PolarHBondContact O-OG1 2.98Å; T344-S347 PolarHBondContact O-OG 3.29Å; T344-T348 PolarHBondContact O-OG1 3.31Å
345	S	38	Very low	41.1	Very low	66 Å²	66	110 Å²	110	46%	0.462	60%	0.603	S	S	.	*	H	α-helix	trans	-80.4	-24.6	171.8	55	0	0	0	0	114	T341 I342	T341-S345 PolarHBondContact O-N 3.07Å; T341-S345 PolarHBondContact O-OG 3.45Å; I342-S345 PolarHBondContact O-OG 3.39Å
346	C	38.6	Very low	41.3	Very low	89 Å²	89	110.8 Å²	110.8	60%	0.601	61%	0.614	S	S	*	*	H	α-helix	trans	-84.8	-26.3	176.9	-108.9	0	0	0	0	113	I342 Q343	I342-C346 PolarHBondContact O-N 3.39Å; Q343-C346 PolarHBondContact O-N 2.83Å
347	S	42.4	Very low	41.4	Very low	64 Å²	64	113.7 Å²	113.7	45%	0.448	63%	0.63	S	S	.	*	H	α-helix	trans	-78.4	-27.8	177.8	55.5	0	0	0	0	113.4	Q343 T344 Q349	Q343-S347 PolarHBondContact O-N 2.98Å; Q343-S347 PolarHBondContact O-OG 3.41Å; T344-S347 PolarHBondContact O-OG 3.29Å; S347-Q349 VanDerWaalsContact C-N 3.34Å
348	T	40.2	Very low	41.5	Very low	106 Å²	106	116.4 Å²	116.4	65%	0.65	66%	0.658	S	S	*	*	H	α-helix	trans	-78.8	-16.1	177.8	36	0	0	0	0	113.6	T344	T344-T348 PolarHBondContact O-OG1 3.31Å
349	Q	40.8	Very low	41.7	Very low	156 Å²	156	118.6 Å²	118.6	73%	0.729	67%	0.669	S	S	*	*	H	α-helix	trans	-91.6	-15.5	176.7	-134.8	173.8	15	0	0	113.5	S347	S347-Q349 VanDerWaalsContact C-N 3.34Å
350	S	40	Very low	41.6	Very low	73 Å²	73	118.5 Å²	118.5	51%	0.51	67%	0.674	S	S	.	*	H	α-helix	trans	-86.2	-19.2	-179.2	-170.6	0	0	0	0	114.2
351	D	40.7	Very low	41.4	Very low	134 Å²	134	119.9 Å²	119.9	72%	0.717	68%	0.684	S	S	*	*	S	Bend	trans	-96.8	-11.5	-178.8	-72.9	-22.3	0	0	0	113.4
352	A	42.4	Very low	41.5	Very low	85 Å²	85	121.8 Å²	121.8	70%	0.702	69%	0.692	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.2	-9.3	177.4	0	0	0	0	0	114.2
353	S	42.4	Very low	41.4	Very low	93 Å²	93	122.9 Å²	122.9	65%	0.65	70%	0.702	S	S	*	*	T	Hydrogen-bonded Turn	trans	-108.2	10.8	-176.5	66.5	0	0	0	0	114.6
354	K	43.1	Very low	41.4	Very low	188 Å²	188	121.9 Å²	121.9	82%	0.817	71%	0.706	S	S	*	*	S	Bend	trans	-112.8	13.9	177.5	-87.5	-170.3	176.5	-176.3	0	114.9
355	Q	43.2	Very low	41.4	Very low	186 Å²	186	124.3 Å²	124.3	87%	0.869	72%	0.718	S	S	*	*	S	Bend	trans	-128.8	49.3	178.5	-148.9	148.9	6.1	0	0	111.6
356	A	43.7	Very low	41.6	Very low	86 Å²	86	128.8 Å²	128.8	71%	0.711	74%	0.738	S	S	*	*	S	Bend	trans	-144.1	16.5	172.4	0	0	0	0	0	113.8
357	D	44	Very low	41.9	Very low	161 Å²	161	132.1 Å²	132.1	86%	0.861	75%	0.749	S	S	*	*			trans	-147.5	83	170.2	-82.4	-44.3	0	0	0	109.8
358	L	39.8	Very low	41.8	Very low	253 Å²	253	138.3 Å²	138.3	100%	1.325	78%	0.777	S	S	*	*			trans	-170.3	0	145.9	-106.9	149.3	0	0	0	110.3

Retrieved 358 of 358 residues in 899.1 ms (Link to these results)

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