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Hepatic sodium/bile acid cotransporter

As a major transporter of conjugated bile salts from plasma into the hepatocyte, it plays a key role in the enterohepatic circulation of bile salts necessary for the solubilization and absorption of dietary fat and fat-soluble vitamins. It is strictly dependent on the extracellular presence of sodium. It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate. Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation.

AlphaFold DB , UniProt , Accession A0A096NVU6, Species PAPAN (Papio anubis, Olive baboon), Gene SLC10A1, Length 349 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.5	Very low	34.7	Very low	249 Å²	249	141 Å²	141	100%	1.227	81%	0.806	S	S	*	*				0	91.6	0	-91.6	176	170.6	0	0	107.2
2	E	33.5	Very low	36.3	Very low	188 Å²	188	135.5 Å²	135.5	88%	0.879	77%	0.766	S	S	*	*			trans	-76.1	120.6	173.5	-68.8	166.3	135.9	0	0	108
3	A	31.2	Very low	37.7	Very low	99 Å²	99	133.8 Å²	133.8	82%	0.818	76%	0.761	S	S	*	*			trans	-99.4	101	166.4	0	0	0	0	0	107.6	N5	A3-N5 PolarHBondContact O-N 2.84Å; A3-N5 VanDerWaalsContact O-N 3.08Å
4	H	33.3	Very low	39.2	Very low	180 Å²	180	127.7 Å²	127.7	83%	0.833	72%	0.724	S	S	*	*			trans	-53.7	107.5	162.3	-91.4	-84.3	0	0	0	109.4
5	N	30	Very low	40.5	Very low	154 Å²	154	120.9 Å²	120.9	82%	0.824	69%	0.687	S	S	*	*			trans	-107.3	84.8	161.4	-136.9	5.3	0	0	0	107.5	A3 S7	A3-N5 PolarHBondContact O-N 2.84Å; A3-N5 VanDerWaalsContact O-N 3.08Å; N5-S7 PolarHBondContact O-N 2.9Å
6	A	35.7	Very low	41.4	Very low	96 Å²	96	119.7 Å²	119.7	79%	0.793	69%	0.685	S	S	*	*			trans	-77.2	73.4	175	0	0	0	0	0	109.7
7	S	33.4	Very low	42.4	Very low	97 Å²	97	119.5 Å²	119.5	68%	0.678	68%	0.682	S	S	*	*			trans	-87.1	97.4	152.3	54.1	0	0	0	0	106.3	N5 P9	N5-S7 PolarHBondContact O-N 2.9Å; S7-P9 WeakPolarHBondContact O-CD 3.33Å; S7-P9 VanDerWaalsContact O-N 3.09Å
8	A	32.5	Very low	43.3	Very low	85 Å²	85	114 Å²	114	70%	0.702	65%	0.649	S	S	*	*			trans	-51.8	119.6	171	0	0	0	0	0	108	F10	A8-F10 PolarHBondContact O-N 2.82Å
9	P	41.3	Very low	44.2	Very low	98 Å²	98	109.6 Å²	109.6	64%	0.636	63%	0.631	S	S	*	*			trans	-66.7	115.8	169.1	27.4	-27.5	0	0	0	104.4	S7 N11	S7-P9 WeakPolarHBondContact O-CD 3.33Å; S7-P9 VanDerWaalsContact O-N 3.09Å; P9-N11 PolarHBondContact O-N 3.35Å
10	F	38.6	Very low	45.3	Very low	167 Å²	167	112.6 Å²	112.6	73%	0.732	64%	0.636	S	S	*	*			trans	-58.6	94.8	159.2	-105.4	-86	0	0	0	105.1	A8 F12	A8-F10 PolarHBondContact O-N 2.82Å; F10-F12 PolarHBondContact O-N 3.47Å
11	N	38.7	Very low	46.7	Very low	138 Å²	138	110.3 Å²	110.3	74%	0.738	62%	0.618	S	S	*	*			trans	-63.1	95.5	175	-90.1	-18.3	0	0	0	106.3	P9 T13	P9-N11 PolarHBondContact O-N 3.35Å; N11-T13 PolarHBondContact O-N 2.98Å; N11-T13 VanDerWaalsContact O-N 3.15Å
12	F	54.1	Low	49	Very low	75 Å²	75	103.6 Å²	103.6	33%	0.329	59%	0.593	S	S	.	*			trans	-72.6	101.8	179.5	169.4	-108.5	0	0	0	108.1	F10 L14 F216 P281	F10-F12 PolarHBondContact O-N 3.47Å; F12-L14 HydrophobicContact CD1-CG 4.39Å; F12-L14 HydrophobicContact CE1-CD1 4.01Å; F12-L14 HydrophobicContact CE1-CD2 3.75Å; F12-L14 HydrophobicContact CE1-CG 3.43Å; F12-L14 VanDerWaalsContact CE1-CG 3.43Å; F12-L14 HydrophobicContact CE2-CD2 4.21Å; F12-L14 HydrophobicContact CE2-CG 4.48Å; F12-L14 HydrophobicContact CZ-CD1 4.39Å; F12-L14 HydrophobicContact CZ-CD2 3.26Å; F12-L14 HydrophobicContact CZ-CG 3.48Å; F12-L14 VanDerWaalsContact CZ-CG 3.48Å; F12-F216 HydrophobicContact CB-CE2 4.48Å; F12-F216 HydrophobicContact CD2-CD2 4.41Å; F12-F216 HydrophobicContact CD2-CG 4.48Å; F12-P281 VanDerWaalsContact CE2-CD 3.41Å; F12-P281 HydrophobicContact CE2-CG 3.79Å; F12-P281 HydrophobicContact CZ-CG 4.19Å
13	T	53.8	Low	51.1	Low	114 Å²	114	96.8 Å²	96.8	70%	0.699	56%	0.564	S	S	*	*			trans	-97.5	109.5	170.5	-40.4	0	0	0	0	108	N11	N11-T13 PolarHBondContact O-N 2.98Å; N11-T13 VanDerWaalsContact O-N 3.15Å
14	L	58.9	Low	53.3	Low	48 Å²	48	92.6 Å²	92.6	25%	0.251	53%	0.528	S	S	.	.	P	Polyproline II helix	trans	-55.7	142.5	168.6	-81.7	165	0	0	0	109.6	F12 F18	F12-L14 HydrophobicContact CD1-CG 4.39Å; F12-L14 HydrophobicContact CE1-CD1 4.01Å; F12-L14 HydrophobicContact CE1-CD2 3.75Å; F12-L14 HydrophobicContact CE1-CG 3.43Å; F12-L14 VanDerWaalsContact CE1-CG 3.43Å; F12-L14 HydrophobicContact CE2-CD2 4.21Å; F12-L14 HydrophobicContact CE2-CG 4.48Å; F12-L14 HydrophobicContact CZ-CD1 4.39Å; F12-L14 HydrophobicContact CZ-CD2 3.26Å; F12-L14 HydrophobicContact CZ-CG 3.48Å; F12-L14 VanDerWaalsContact CZ-CG 3.48Å; L14-F18 HydrophobicContact CB-CB 4.34Å; L14-F18 HydrophobicContact CD2-CB 4.1Å; L14-F18 HydrophobicContact CD2-CD1 3.46Å; L14-F18 VanDerWaalsContact CD2-CD1 3.46Å; L14-F18 HydrophobicContact CD2-CE1 3.96Å; L14-F18 HydrophobicContact CD2-CG 3.81Å
15	P	59.2	Low	55.6	Low	25 Å²	25	89.3 Å²	89.3	16%	0.162	52%	0.516	C	S	.	.	P	Polyproline II helix	trans	-53.1	140.4	168.7	-19.4	28.9	0	0	0	110	N17 F18 N209	P15-N17 PolarHBondContact O-N 3.34Å; P15-F18 HydrophobicContact CG-CD2 4.15Å; P15-F18 WeakPolarHBondContact O-CB 3.49Å; P15-F18 PolarHBondContact O-N 2.58Å; P15-N209 WeakPolarHBondContact CG-O 3.45Å
16	P	55.1	Low	58.2	Low	102 Å²	102	83.7 Å²	83.7	66%	0.662	49%	0.491	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.5	132.9	-179.9	20.7	-31.4	0	0	0	110.8	F18 R21	P16-F18 VanDerWaalsContact C-N 3.34Å; P16-F18 PolarHBondContact O-N 3.12Å; P16-R21 VanDerWaalsContact O-CZ 3.23Å; P16-R21 PolarHBondContact O-NE 3.3Å; P16-R21 PolarHBondContact O-NH2 2.94Å
17	N	57.5	Low	60.4	Low	117 Å²	117	79.3 Å²	79.3	63%	0.626	45%	0.454	S	S	*	.	T	Hydrogen-bonded Turn	trans	66.2	18.9	-174.2	-59.8	-38.3	0	0	0	116.5	P15 G19 K20 R21	P15-N17 PolarHBondContact O-N 3.34Å; N17-G19 PolarHBondContact O-N 3.37Å; N17-K20 HydrophobicContact CB-CB 4.41Å; N17-K20 WeakPolarHBondContact O-CA 3.32Å; N17-K20 PolarHBondContact O-N 3.33Å; N17-R21 HydrophobicContact CB-CG 4.3Å; N17-R21 WeakPolarHBondContact O-CG 2.99Å; N17-R21 PolarHBondContact O-N 2.67Å
18	F	59.6	Low	62.7	Low	20 Å²	20	76.1 Å²	76.1	9%	0.088	43%	0.432	C	S	.	.	T	Hydrogen-bonded Turn	trans	-52.8	129.6	172.3	-168.3	-102.8	0	0	0	111.2	L14 P15 P16 K20 V210 P276 F283	L14-F18 HydrophobicContact CB-CB 4.34Å; L14-F18 HydrophobicContact CD2-CB 4.1Å; L14-F18 HydrophobicContact CD2-CD1 3.46Å; L14-F18 VanDerWaalsContact CD2-CD1 3.46Å; L14-F18 HydrophobicContact CD2-CE1 3.96Å; L14-F18 HydrophobicContact CD2-CG 3.81Å; P15-F18 HydrophobicContact CG-CD2 4.15Å; P15-F18 WeakPolarHBondContact O-CB 3.49Å; P15-F18 PolarHBondContact O-N 2.58Å; P16-F18 VanDerWaalsContact C-N 3.34Å; P16-F18 PolarHBondContact O-N 3.12Å; F18-K20 VanDerWaalsContact C-N 3.33Å; F18-V210 HydrophobicContact CE2-CG2 3.78Å; F18-V210 HydrophobicContact CZ-CG2 4.07Å; F18-P276 HydrophobicContact CD1-CB 4.03Å; F18-P276 HydrophobicContact CE1-CB 4.09Å; F18-F283 HydrophobicContact CZ-CE1 4.44Å
19	G	60.3	Low	65.4	Low	30 Å²	30	77 Å²	77	31%	0.309	42%	0.423	S	S	.	.	T	Hydrogen-bonded Turn	trans	90.5	-19	-172.4	0	0	0	0	0	114.8	N17 D24	N17-G19 PolarHBondContact O-N 3.37Å; G19-D24 PolarHBondContact N-OD2 3.42Å
20	K	66.4	Low	67.5	Low	169 Å²	169	74.1 Å²	74.1	74%	0.735	40%	0.403	S	S	*	.	T	Hydrogen-bonded Turn	trans	-109	-3.3	177.7	-62.1	-177.7	-176.6	176.7	0	113.2	N17 F18	N17-K20 HydrophobicContact CB-CB 4.41Å; N17-K20 WeakPolarHBondContact O-CA 3.32Å; N17-K20 PolarHBondContact O-N 3.33Å; F18-K20 VanDerWaalsContact C-N 3.33Å
21	R	74.9	Confident	69.7	Low	65 Å²	65	66.4 Å²	66.4	25%	0.245	37%	0.369	C	S	.	.	S	Bend	trans	-75.7	147.6	177.7	-63.2	164.9	178.6	-165.9	-6	110.2	P16 N17 T23 D24 L25	P16-R21 VanDerWaalsContact O-CZ 3.23Å; P16-R21 PolarHBondContact O-NE 3.3Å; P16-R21 PolarHBondContact O-NH2 2.94Å; N17-R21 HydrophobicContact CB-CG 4.3Å; N17-R21 WeakPolarHBondContact O-CG 2.99Å; N17-R21 PolarHBondContact O-N 2.67Å; R21-T23 WeakPolarHBondContact CB-OG1 3.44Å; R21-T23 PolarHBondContact O-N 3.39Å; R21-T23 VanDerWaalsContact O-N 3.15Å; R21-D24 WeakPolarHBondContact CB-OD2 3.26Å; R21-D24 PolarHBondContact O-N 3.36Å; R21-L25 PolarHBondContact O-N 2.91Å
22	P	80.2	Confident	72.1	Confident	108 Å²	108	62.9 Å²	62.9	70%	0.701	35%	0.352	S	S	*	.	H	α-helix	trans	-58.8	-28.1	173.3	23.8	-33.2	0	0	0	112.2	A26	P22-A26 VanDerWaalsContact O-CB 3.3Å; P22-A26 WeakPolarHBondContact O-CB 2.98Å; P22-A26 PolarHBondContact O-N 2.86Å
23	T	78.6	Confident	73.8	Confident	45 Å²	45	64.4 Å²	64.4	28%	0.276	36%	0.359	S	S	.	.	H	α-helix	trans	-71.4	-31.7	176	50.8	0	0	0	0	113.3	R21 L27 N209	R21-T23 WeakPolarHBondContact CB-OG1 3.44Å; R21-T23 PolarHBondContact O-N 3.39Å; R21-T23 VanDerWaalsContact O-N 3.15Å; T23-L27 WeakPolarHBondContact O-CB 3.36Å; T23-L27 PolarHBondContact O-N 2.94Å; T23-N209 WeakPolarHBondContact CB-OD1 3.06Å; T23-N209 PolarHBondContact O-ND2 3.18Å; T23-N209 PolarHBondContact OG1-OD1 2.99Å
24	D	76.6	Confident	75.4	Confident	12 Å²	12	59.8 Å²	59.8	6%	0.064	33%	0.329	C	S	.	.	H	α-helix	trans	-74	-39.5	175.6	-61.9	-41.3	0	0	0	110.6	G19 R21 L27 S28 N209	G19-D24 PolarHBondContact N-OD2 3.42Å; R21-D24 WeakPolarHBondContact CB-OD2 3.26Å; R21-D24 PolarHBondContact O-N 3.36Å; D24-L27 PolarHBondContact O-N 3.49Å; D24-S28 PolarHBondContact O-N 3.13Å; D24-S28 PolarHBondContact O-OG 2.89Å; D24-N209 VanDerWaalsContact OD1-CG 3.3Å; D24-N209 PolarHBondContact OD1-ND2 2.95Å
25	L	81.7	Confident	76.8	Confident	110 Å²	110	57.9 Å²	57.9	58%	0.576	32%	0.319	S	S	*	.	H	α-helix	trans	-62.3	-46.3	171.7	-179	64.3	0	0	0	111.2	R21 L27 S28 I29	R21-L25 PolarHBondContact O-N 2.91Å; L25-L27 VanDerWaalsContact C-N 3.34Å; L25-L27 PolarHBondContact O-N 2.87Å; L25-S28 PolarHBondContact O-N 3.44Å; L25-I29 HydrophobicContact CD1-CD1 4.23Å; L25-I29 HydrophobicContact CD1-CG1 4.49Å; L25-I29 HydrophobicContact CG-CD1 3.98Å; L25-I29 WeakPolarHBondContact O-CG1 3.32Å; L25-I29 PolarHBondContact O-N 3.09Å
26	A	84.7	Confident	78.3	Confident	36 Å²	36	60.2 Å²	60.2	30%	0.298	33%	0.327	S	S	.	.	H	α-helix	trans	-60	-43.3	176.4	0	0	0	0	0	111.8	P22 S28 I29 I30 L205	P22-A26 VanDerWaalsContact O-CB 3.3Å; P22-A26 WeakPolarHBondContact O-CB 2.98Å; P22-A26 PolarHBondContact O-N 2.86Å; A26-S28 VanDerWaalsContact C-N 3.33Å; A26-S28 PolarHBondContact O-N 2.89Å; A26-I29 PolarHBondContact O-N 3.4Å; A26-I30 WeakPolarHBondContact O-CB 3.11Å; A26-I30 WeakPolarHBondContact O-CD1 3.29Å; A26-I30 WeakPolarHBondContact O-CG1 3.35Å; A26-I30 PolarHBondContact O-N 2.96Å; A26-L205 HydrophobicContact CB-CD2 3.78Å
27	L	81.9	Confident	79.9	Confident	4 Å²	4	57 Å²	57	2%	0.021	30%	0.303	C	S	.	.	H	α-helix	trans	-58.5	-46.8	175.4	-174.2	154.3	0	0	0	110.9	T23 D24 L25 I29 I30 L31 L205 F283	T23-L27 WeakPolarHBondContact O-CB 3.36Å; T23-L27 PolarHBondContact O-N 2.94Å; D24-L27 PolarHBondContact O-N 3.49Å; L25-L27 VanDerWaalsContact C-N 3.34Å; L25-L27 PolarHBondContact O-N 2.87Å; L27-I29 PolarHBondContact O-N 3.49Å; L27-I30 PolarHBondContact O-N 3.03Å; L27-L31 HydrophobicContact CD2-CD1 3.49Å; L27-L31 VanDerWaalsContact CD2-CD1 3.49Å; L27-L31 HydrophobicContact CD2-CG 4.04Å; L27-L31 WeakPolarHBondContact O-CG 3.34Å; L27-L31 PolarHBondContact O-N 3.3Å; L27-L205 HydrophobicContact CB-CD2 4.13Å; L27-L205 HydrophobicContact CD1-CB 4.45Å; L27-F283 HydrophobicContact CD1-CE2 4.27Å; L27-F283 HydrophobicContact CD1-CZ 4.12Å; L27-F283 HydrophobicContact CD2-CE2 4.13Å; L27-F283 HydrophobicContact CD2-CZ 4.49Å
28	S	83.1	Confident	81.4	Confident	31 Å²	31	52.2 Å²	52.2	22%	0.217	28%	0.278	C	S	.	.	H	α-helix	trans	-61.4	-45.2	179.6	-51.4	0	0	0	0	111.8	D24 L25 A26 L31 V32 N271	D24-S28 PolarHBondContact O-N 3.13Å; D24-S28 PolarHBondContact O-OG 2.89Å; L25-S28 PolarHBondContact O-N 3.44Å; A26-S28 VanDerWaalsContact C-N 3.33Å; A26-S28 PolarHBondContact O-N 2.89Å; S28-L31 PolarHBondContact O-N 2.92Å; S28-V32 WeakPolarHBondContact O-CG2 3.22Å; S28-V32 PolarHBondContact O-N 3.29Å; S28-V32 VanDerWaalsContact O-N 3.07Å; S28-N271 WeakPolarHBondContact CA-OD1 3.3Å; S28-N271 WeakPolarHBondContact CB-OD1 3.26Å; S28-N271 PolarHBondContact OG-OD1 3.45Å; S28-N271 VanDerWaalsContact OG-OD1 3.08Å
29	I	87.4	Confident	82.9	Confident	102 Å²	102	51.2 Å²	51.2	52%	0.523	27%	0.273	S	S	.	.	H	α-helix	trans	-62.4	-45.6	177	-68.2	168.2	0	0	0	110.8	L25 A26 L27 L31 V32 F33	L25-I29 HydrophobicContact CD1-CD1 4.23Å; L25-I29 HydrophobicContact CD1-CG1 4.49Å; L25-I29 HydrophobicContact CG-CD1 3.98Å; L25-I29 WeakPolarHBondContact O-CG1 3.32Å; L25-I29 PolarHBondContact O-N 3.09Å; A26-I29 PolarHBondContact O-N 3.4Å; L27-I29 PolarHBondContact O-N 3.49Å; I29-L31 VanDerWaalsContact C-N 3.34Å; I29-L31 PolarHBondContact O-N 3.39Å; I29-V32 PolarHBondContact O-N 2.61Å; I29-F33 WeakPolarHBondContact O-CB 3.39Å; I29-F33 PolarHBondContact O-N 3.44Å
30	I	86.7	Confident	84.4	Confident	39 Å²	39	50.8 Å²	50.8	20%	0.2	26%	0.264	C	S	.	.	H	α-helix	trans	-64.1	-40.4	179.5	-65.2	163.4	0	0	0	110.6	A26 L27 F33 M34 C198 A201 V202 L205	A26-I30 WeakPolarHBondContact O-CB 3.11Å; A26-I30 WeakPolarHBondContact O-CD1 3.29Å; A26-I30 WeakPolarHBondContact O-CG1 3.35Å; A26-I30 PolarHBondContact O-N 2.96Å; L27-I30 PolarHBondContact O-N 3.03Å; I30-F33 PolarHBondContact O-N 3.16Å; I30-M34 WeakPolarHBondContact O-CB 3.44Å; I30-M34 PolarHBondContact O-N 3.4Å; I30-C198 HydrophobicContact CG2-CB 4.01Å; I30-A201 HydrophobicContact CD1-CB 4.31Å; I30-V202 HydrophobicContact CB-CG2 4.38Å; I30-V202 HydrophobicContact CG2-CG2 3.61Å; I30-L205 HydrophobicContact CD1-CD2 4.12Å
31	L	84.2	Confident	85.4	Confident	5 Å²	5	43.3 Å²	43.3	3%	0.026	23%	0.233	C	C	.	.	H	α-helix	trans	-61.8	-44.5	176.6	-78.5	-179.9	0	0	0	112.4	L27 S28 I29 M34 L35 V202 Q264 N271	L27-L31 HydrophobicContact CD2-CD1 3.49Å; L27-L31 VanDerWaalsContact CD2-CD1 3.49Å; L27-L31 HydrophobicContact CD2-CG 4.04Å; L27-L31 WeakPolarHBondContact O-CG 3.34Å; L27-L31 PolarHBondContact O-N 3.3Å; S28-L31 PolarHBondContact O-N 2.92Å; I29-L31 VanDerWaalsContact C-N 3.34Å; I29-L31 PolarHBondContact O-N 3.39Å; L31-M34 PolarHBondContact O-N 3.38Å; L31-L35 VanDerWaalsContact O-CB 3.3Å; L31-L35 WeakPolarHBondContact O-CB 3.4Å; L31-L35 PolarHBondContact O-N 3.24Å; L31-V202 HydrophobicContact CD2-CG1 4.01Å; L31-V202 HydrophobicContact CD2-CG2 3.9Å; L31-V202 HydrophobicContact CG-CG2 4.36Å; L31-Q264 PolarHBondContact O-NE2 3.07Å; L31-N271 HydrophobicContact CD1-CB 3.89Å
32	V	88.3	Confident	86	Confident	63 Å²	63	40.3 Å²	40.3	38%	0.382	22%	0.221	S	C	.	.	H	α-helix	trans	-64.5	-43.7	176.6	172.9	0	0	0	0	110.7	S28 I29 L35 F36 T268 V272	S28-V32 WeakPolarHBondContact O-CG2 3.22Å; S28-V32 PolarHBondContact O-N 3.29Å; S28-V32 VanDerWaalsContact O-N 3.07Å; I29-V32 PolarHBondContact O-N 2.61Å; V32-L35 PolarHBondContact O-N 2.97Å; V32-F36 PolarHBondContact O-N 3.04Å; V32-T268 HydrophobicContact CG2-CG2 3.94Å; V32-V272 HydrophobicContact CG2-CG2 3.95Å
33	F	89.9	Confident	86.4	Confident	108 Å²	108	35.1 Å²	35.1	47%	0.474	19%	0.188	S	C	.	.	H	α-helix	trans	-64.2	-45.3	177.7	-165	-105.5	0	0	0	111.5	I29 I30 L35 F36 F37 I194	I29-F33 WeakPolarHBondContact O-CB 3.39Å; I29-F33 PolarHBondContact O-N 3.44Å; I30-F33 PolarHBondContact O-N 3.16Å; F33-L35 VanDerWaalsContact C-N 3.35Å; F33-L35 PolarHBondContact O-N 3.08Å; F33-F36 WeakPolarHBondContact O-CB 3.36Å; F33-F36 PolarHBondContact O-N 2.92Å; F33-F37 AromaticContact CD1-CD2 3.96Å; F33-F37 HydrophobicContact CD1-CD2 3.96Å; F33-F37 AromaticContact CD1-CE2 3.74Å; F33-F37 HydrophobicContact CD1-CE2 3.74Å; F33-F37 HydrophobicContact CD2-CE2 4.17Å; F33-F37 AromaticContact CE1-CD2 3.89Å; F33-F37 HydrophobicContact CE1-CD2 3.89Å; F33-F37 AromaticContact CE1-CE2 3.27Å; F33-F37 HydrophobicContact CE1-CE2 3.27Å; F33-F37 HydrophobicContact CE1-CZ 4.15Å; F33-F37 AromaticContact CE2-CE2 3.75Å; F33-F37 HydrophobicContact CE2-CE2 3.75Å; F33-F37 HydrophobicContact CE2-CZ 4.49Å; F33-F37 HydrophobicContact CG-CD2 4.44Å; F33-F37 HydrophobicContact CG-CE2 4.19Å; F33-F37 HydrophobicContact CZ-CD2 4.31Å; F33-F37 AromaticContact CZ-CE2 3.3Å; F33-F37 HydrophobicContact CZ-CE2 3.3Å; F33-F37 AromaticContact CZ-CZ 3.93Å; F33-F37 HydrophobicContact CZ-CZ 3.93Å; F33-F37 VanDerWaalsContact O-CD2 3.29Å; F33-F37 WeakPolarHBondContact O-CD2 3.1Å; F33-F37 PolarHBondContact O-N 3.39Å; F33-F37 VanDerWaalsContact O-N 3.16Å; F33-I194 HydrophobicContact CE1-CG2 4.11Å
34	M	87.5	Confident	86.9	Confident	16 Å²	16	33 Å²	33	8%	0.079	18%	0.175	C	C	.	.	H	α-helix	trans	-59.8	-45.4	175.2	-175.5	178.5	173.5	0	0	111.2	I30 L31 F36 F37 V38 I195 C198 Q264	I30-M34 WeakPolarHBondContact O-CB 3.44Å; I30-M34 PolarHBondContact O-N 3.4Å; L31-M34 PolarHBondContact O-N 3.38Å; M34-F36 VanDerWaalsContact C-N 3.3Å; M34-F36 PolarHBondContact O-N 3.16Å; M34-F37 PolarHBondContact O-N 2.89Å; M34-V38 VanDerWaalsContact O-CG2 3.3Å; M34-V38 WeakPolarHBondContact O-CG2 3.47Å; M34-V38 PolarHBondContact O-N 2.65Å; M34-I195 HydrophobicContact CE-CG2 3.88Å; M34-C198 HydrophobicContact CB-CB 3.83Å; M34-C198 HydrophobicContact CG-CB 3.9Å; M34-C198 HydrophobicContact SD-CB 4.01Å; M34-Q264 PolarHBondContact SD-NE2 3.19Å
35	L	88.1	Confident	87.2	Confident	8 Å²	8	35.1 Å²	35.1	4%	0.042	19%	0.189	C	C	.	.	H	α-helix	trans	-58.6	-42.3	175.6	-179.8	62.7	0	0	0	111.7	L31 V32 F33 F37 V38 M39 V166 Q264 L265 T268	L31-L35 VanDerWaalsContact O-CB 3.3Å; L31-L35 WeakPolarHBondContact O-CB 3.4Å; L31-L35 PolarHBondContact O-N 3.24Å; V32-L35 PolarHBondContact O-N 2.97Å; F33-L35 VanDerWaalsContact C-N 3.35Å; F33-L35 PolarHBondContact O-N 3.08Å; L35-F37 PolarHBondContact O-N 3.35Å; L35-V38 PolarHBondContact O-N 3.07Å; L35-M39 HydrophobicContact CD1-CE 3.47Å; L35-M39 VanDerWaalsContact CD1-CE 3.47Å; L35-M39 HydrophobicContact CD1-CG 4Å; L35-M39 HydrophobicContact CD1-SD 4.48Å; L35-M39 HydrophobicContact CG-CG 4.33Å; L35-M39 WeakPolarHBondContact O-CB 3.4Å; L35-M39 WeakPolarHBondContact O-CG 3.34Å; L35-M39 PolarHBondContact O-N 3.47Å; L35-V166 HydrophobicContact CD2-CG2 3.86Å; L35-V166 HydrophobicContact CG-CG2 4.42Å; L35-Q264 HydrophobicContact CB-CG 4.05Å; L35-Q264 HydrophobicContact CD1-CB 4.22Å; L35-Q264 HydrophobicContact CD1-CG 3.91Å; L35-L265 HydrophobicContact CD1-CB 4.05Å; L35-T268 HydrophobicContact CD2-CG2 3.67Å
36	F	91.1	Very high	87.2	Confident	75 Å²	75	30 Å²	30	33%	0.329	16%	0.162	S	C	.	.	H	α-helix	trans	-56.1	-49.2	176	177.5	-86.6	0	0	0	111.7	V32 F33 M34 M39 L40 P169	V32-F36 PolarHBondContact O-N 3.04Å; F33-F36 WeakPolarHBondContact O-CB 3.36Å; F33-F36 PolarHBondContact O-N 2.92Å; M34-F36 VanDerWaalsContact C-N 3.3Å; M34-F36 PolarHBondContact O-N 3.16Å; F36-M39 PolarHBondContact O-N 2.9Å; F36-L40 HydrophobicContact CE1-CD2 4.17Å; F36-L40 VanDerWaalsContact O-CB 3.25Å; F36-L40 WeakPolarHBondContact O-CB 3.49Å; F36-L40 PolarHBondContact O-N 2.79Å; F36-P169 HydrophobicContact CD2-CB 3.62Å; F36-P169 HydrophobicContact CD2-CG 3.78Å; F36-P169 HydrophobicContact CE2-CB 3.7Å; F36-P169 HydrophobicContact CE2-CG 4.23Å; F36-P169 HydrophobicContact CG-CB 4.12Å; F36-P169 HydrophobicContact CG-CG 4.39Å; F36-P169 HydrophobicContact CZ-CB 4.24Å; F36-P169 WeakPolarHBondContact O-CB 3.33Å
37	F	90.3	Very high	87	Confident	35 Å²	35	31.3 Å²	31.3	15%	0.154	16%	0.162	C	C	.	.	H	α-helix	trans	-68.9	-35	178.7	-77.8	-81.7	0	0	0	113.2	F33 M34 L35 S41 I194 I195	F33-F37 AromaticContact CD1-CD2 3.96Å; F33-F37 HydrophobicContact CD1-CD2 3.96Å; F33-F37 AromaticContact CD1-CE2 3.74Å; F33-F37 HydrophobicContact CD1-CE2 3.74Å; F33-F37 HydrophobicContact CD2-CE2 4.17Å; F33-F37 AromaticContact CE1-CD2 3.89Å; F33-F37 HydrophobicContact CE1-CD2 3.89Å; F33-F37 AromaticContact CE1-CE2 3.27Å; F33-F37 HydrophobicContact CE1-CE2 3.27Å; F33-F37 HydrophobicContact CE1-CZ 4.15Å; F33-F37 AromaticContact CE2-CE2 3.75Å; F33-F37 HydrophobicContact CE2-CE2 3.75Å; F33-F37 HydrophobicContact CE2-CZ 4.49Å; F33-F37 HydrophobicContact CG-CD2 4.44Å; F33-F37 HydrophobicContact CG-CE2 4.19Å; F33-F37 HydrophobicContact CZ-CD2 4.31Å; F33-F37 AromaticContact CZ-CE2 3.3Å; F33-F37 HydrophobicContact CZ-CE2 3.3Å; F33-F37 AromaticContact CZ-CZ 3.93Å; F33-F37 HydrophobicContact CZ-CZ 3.93Å; F33-F37 VanDerWaalsContact O-CD2 3.29Å; F33-F37 WeakPolarHBondContact O-CD2 3.1Å; F33-F37 PolarHBondContact O-N 3.39Å; F33-F37 VanDerWaalsContact O-N 3.16Å; M34-F37 PolarHBondContact O-N 2.89Å; L35-F37 PolarHBondContact O-N 3.35Å; F37-S41 VanDerWaalsContact O-CB 3.26Å; F37-S41 WeakPolarHBondContact O-CB 3.39Å; F37-S41 PolarHBondContact O-N 3.38Å; F37-S41 PolarHBondContact O-OG 2.93Å; F37-I194 HydrophobicContact CD1-CD1 4.02Å; F37-I194 HydrophobicContact CD1-CG2 4.42Å; F37-I194 HydrophobicContact CD2-CG2 3.76Å; F37-I194 HydrophobicContact CE1-CD1 3.59Å; F37-I194 HydrophobicContact CE2-CG2 4.08Å; F37-I194 HydrophobicContact CG-CG2 3.98Å; F37-I194 HydrophobicContact CZ-CD1 3.89Å; F37-I194 HydrophobicContact CZ-CG2 4.49Å; F37-I195 HydrophobicContact CB-CD1 4.33Å; F37-I195 HydrophobicContact CB-CG1 3.98Å
38	V	88.4	Confident	86.7	Confident	15 Å²	15	37.4 Å²	37.4	9%	0.091	19%	0.188	C	C	.	.	H	α-helix	trans	-62.8	-47.2	174.9	172.6	0	0	0	0	110.4	M34 L35 S41 L42 I195 Q264	M34-V38 VanDerWaalsContact O-CG2 3.3Å; M34-V38 WeakPolarHBondContact O-CG2 3.47Å; M34-V38 PolarHBondContact O-N 2.65Å; L35-V38 PolarHBondContact O-N 3.07Å; V38-S41 PolarHBondContact O-N 2.91Å; V38-L42 PolarHBondContact O-N 3.32Å; V38-I195 HydrophobicContact CB-CD1 4.44Å; V38-I195 HydrophobicContact CG2-CD1 3.71Å; V38-I195 HydrophobicContact CG2-CG1 3.88Å; V38-I195 HydrophobicContact CG2-CG2 4.2Å; V38-Q264 HydrophobicContact CG2-CG 4.35Å
39	M	90.8	Very high	86.5	Confident	0 Å²	0	39.8 Å²	39.8	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-69.6	-37.6	179.3	-67.3	-49.9	122.6	0	0	112.4	L35 F36 S41 L42 G43 V166 P169 C170 N262	L35-M39 HydrophobicContact CD1-CE 3.47Å; L35-M39 VanDerWaalsContact CD1-CE 3.47Å; L35-M39 HydrophobicContact CD1-CG 4Å; L35-M39 HydrophobicContact CD1-SD 4.48Å; L35-M39 HydrophobicContact CG-CG 4.33Å; L35-M39 WeakPolarHBondContact O-CB 3.4Å; L35-M39 WeakPolarHBondContact O-CG 3.34Å; L35-M39 PolarHBondContact O-N 3.47Å; F36-M39 PolarHBondContact O-N 2.9Å; M39-S41 VanDerWaalsContact C-N 3.33Å; M39-L42 PolarHBondContact O-N 3.15Å; M39-L42 HydrophobicContact SD-CD2 4.36Å; M39-G43 PolarHBondContact O-N 2.89Å; M39-V166 HydrophobicContact CG-CB 4.34Å; M39-V166 HydrophobicContact CG-CG1 3.59Å; M39-V166 HydrophobicContact SD-CG1 3.5Å; M39-V166 VanDerWaalsContact SD-CG1 3.5Å; M39-P169 HydrophobicContact CB-CB 4.1Å; M39-P169 HydrophobicContact CB-CG 3.71Å; M39-C170 HydrophobicContact CB-CB 4.42Å; M39-C170 WeakPolarHBondContact O-CA 3.38Å; M39-N262 WeakPolarHBondContact CE-ND2 3.38Å
40	L	91.4	Very high	85.8	Confident	20 Å²	20	37.8 Å²	37.8	11%	0.105	19%	0.192	C	C	.	.	H	α-helix	trans	-62	-44.2	173.3	-178	66.1	0	0	0	110.9	F36 G43 C44 P169 I172	F36-L40 HydrophobicContact CE1-CD2 4.17Å; F36-L40 VanDerWaalsContact O-CB 3.25Å; F36-L40 WeakPolarHBondContact O-CB 3.49Å; F36-L40 PolarHBondContact O-N 2.79Å; L40-G43 PolarHBondContact O-N 3.3Å; L40-C44 WeakPolarHBondContact O-CB 3.43Å; L40-C44 PolarHBondContact O-N 3.06Å; L40-C44 PolarHBondContact O-SG 2.78Å; L40-P169 HydrophobicContact CB-CB 4.12Å; L40-P169 WeakPolarHBondContact CD1-O 3.23Å; L40-I172 HydrophobicContact CD1-CB 4.24Å; L40-I172 HydrophobicContact CD1-CG2 3.87Å
41	S	88.4	Confident	85.2	Confident	12 Å²	12	37.1 Å²	37.1	8%	0.084	19%	0.189	C	C	.	.	H	α-helix	trans	-63.2	-43.7	177.6	-60.1	0	0	0	0	111.3	F37 V38 M39 C44 T45	F37-S41 VanDerWaalsContact O-CB 3.26Å; F37-S41 WeakPolarHBondContact O-CB 3.39Å; F37-S41 PolarHBondContact O-N 3.38Å; F37-S41 PolarHBondContact O-OG 2.93Å; V38-S41 PolarHBondContact O-N 2.91Å; M39-S41 VanDerWaalsContact C-N 3.33Å; S41-C44 PolarHBondContact O-N 3.37Å; S41-T45 WeakPolarHBondContact O-CG2 3.2Å; S41-T45 PolarHBondContact O-N 2.91Å
42	L	87.7	Confident	85	Confident	2 Å²	2	42.9 Å²	42.9	1%	0.01	21%	0.214	C	C	.	.	H	α-helix	trans	-56.1	-51.7	173	174.3	59.8	0	0	0	110.7	V38 M39 C44 T45 N103 T123	V38-L42 PolarHBondContact O-N 3.32Å; M39-L42 PolarHBondContact O-N 3.15Å; M39-L42 HydrophobicContact SD-CD2 4.36Å; L42-C44 VanDerWaalsContact C-N 3.3Å; L42-C44 PolarHBondContact O-N 2.73Å; L42-T45 PolarHBondContact O-N 2.81Å; L42-T45 PolarHBondContact O-OG1 3.36Å; L42-N103 WeakPolarHBondContact CD1-OD1 3.39Å; L42-T123 HydrophobicContact CD1-CG2 3.93Å; L42-T123 HydrophobicContact CD2-CG2 3.95Å
43	G	87.9	Confident	84.3	Confident	0 Å²	0	42.7 Å²	42.7	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-57.8	-40.2	177.7	0	0	0	0	0	113.2	M39 L40 T45 M46 C170 G173 I174	M39-G43 PolarHBondContact O-N 2.89Å; L40-G43 PolarHBondContact O-N 3.3Å; G43-T45 PolarHBondContact O-N 3.42Å; G43-M46 WeakPolarHBondContact O-CB 3.5Å; G43-M46 PolarHBondContact O-N 3.48Å; G43-M46 VanDerWaalsContact O-N 3.12Å; G43-C170 WeakPolarHBondContact CA-O 3.48Å; G43-G173 CarbonylContact O-C 3.22Å; G43-I174 WeakPolarHBondContact O-CA 3.35Å; G43-I174 PolarHBondContact O-N 2.87Å
44	C	88	Confident	83.5	Confident	1 Å²	1	39.4 Å²	39.4	1%	0.007	21%	0.205	C	C	.	.	H	α-helix	trans	-66.4	-19.1	178	-73.4	0	0	0	0	114.1	L40 S41 L42 M46 K177 M184 I188	L40-C44 WeakPolarHBondContact O-CB 3.43Å; L40-C44 PolarHBondContact O-N 3.06Å; L40-C44 PolarHBondContact O-SG 2.78Å; S41-C44 PolarHBondContact O-N 3.37Å; L42-C44 VanDerWaalsContact C-N 3.3Å; L42-C44 PolarHBondContact O-N 2.73Å; C44-M46 VanDerWaalsContact C-N 3.31Å; C44-K177 WeakPolarHBondContact O-CD 3.39Å; C44-K177 WeakPolarHBondContact O-CG 3.34Å; C44-M184 HydrophobicContact CB-SD 3.84Å; C44-I188 HydrophobicContact CB-CD1 4.33Å; C44-I188 HydrophobicContact CB-CG1 4.09Å
45	T	84	Confident	82.9	Confident	56 Å²	56	43.3 Å²	43.3	34%	0.344	23%	0.225	S	C	.	.	T	Hydrogen-bonded Turn	trans	-83.2	-9.5	175.2	63.3	0	0	0	0	113.3	S41 L42 G43 I188	S41-T45 WeakPolarHBondContact O-CG2 3.2Å; S41-T45 PolarHBondContact O-N 2.91Å; L42-T45 PolarHBondContact O-N 2.81Å; L42-T45 PolarHBondContact O-OG1 3.36Å; G43-T45 PolarHBondContact O-N 3.42Å; T45-I188 HydrophobicContact CG2-CD1 4.11Å
46	M	81.6	Confident	82.1	Confident	2 Å²	2	52.5 Å²	52.5	1%	0.01	26%	0.26	C	S	.	.			trans	-98.3	132.9	-169.4	179.1	51.8	117.4	0	0	113.2	G43 C44 I51 I120 V121 T124 I174 K177	G43-M46 WeakPolarHBondContact O-CB 3.5Å; G43-M46 PolarHBondContact O-N 3.48Å; G43-M46 VanDerWaalsContact O-N 3.12Å; C44-M46 VanDerWaalsContact C-N 3.31Å; M46-I51 HydrophobicContact CE-CD1 3.64Å; M46-I51 HydrophobicContact CE-CG1 3.17Å; M46-I51 HydrophobicContact CG-CD1 3.55Å; M46-I51 HydrophobicContact CG-CG1 4Å; M46-I51 HydrophobicContact SD-CD1 3.8Å; M46-I51 HydrophobicContact SD-CG1 3.5Å; M46-I51 VanDerWaalsContact SD-CG1 3.5Å; M46-I120 HydrophobicContact CB-CG2 4.18Å; M46-I120 HydrophobicContact CE-CG2 3.87Å; M46-I120 WeakPolarHBondContact CE-O 3.33Å; M46-I120 HydrophobicContact CG-CG2 4.48Å; M46-I120 HydrophobicContact SD-CG2 3.66Å; M46-V121 HydrophobicContact CE-CB 4.27Å; M46-V121 HydrophobicContact CE-CG2 3.79Å; M46-T124 HydrophobicContact CE-CG2 3.91Å; M46-T124 VanDerWaalsContact CE-OG1 3.26Å; M46-T124 WeakPolarHBondContact CE-OG1 3.22Å; M46-I174 HydrophobicContact CB-CG1 4.08Å; M46-I174 HydrophobicContact CG-CG1 4.16Å; M46-K177 WeakPolarHBondContact O-CG 3.29Å
47	E	80	Confident	81.2	Confident	64 Å²	64	55 Å²	55	30%	0.299	27%	0.27	S	S	.	.			trans	-107.7	126.1	176.5	-72.8	172.5	-176.5	0	0	110.8	S49 K50 I51 K177	E47-S49 PolarHBondContact O-N 2.91Å; E47-K50 HydrophobicContact CB-CB 4.43Å; E47-K50 HydrophobicContact CB-CD 4.08Å; E47-K50 HydrophobicContact CB-CG 4.06Å; E47-K50 WeakPolarHBondContact O-CB 3.41Å; E47-K50 PolarHBondContact O-N 3.14Å; E47-K50 WeakPolarHBondContact OE2-CE 3.28Å; E47-K50 IonicContact OE2-NZ 3.8Å; E47-K50 PolarHBondContact OE2-NZ 3.46Å; E47-I51 PolarHBondContact O-N 2.9Å; E47-K177 VanDerWaalsContact CG-CE 3.45Å; E47-K177 WeakPolarHBondContact OE1-CE 3.18Å; E47-K177 IonicContact OE1-NZ 3.12Å; E47-K177 PolarHBondContact OE1-NZ 2.78Å; E47-K177 VanDerWaalsContact OE1-NZ 3.12Å
48	F	76.9	Confident	80.6	Confident	131 Å²	131	56.8 Å²	56.8	58%	0.575	29%	0.286	S	S	*	.	H	α-helix	trans	-58.8	-35.2	-176.9	-171.1	-98.7	0	0	0	113.2	K50 I51 K52	F48-K50 VanDerWaalsContact C-N 3.27Å; F48-K50 PolarHBondContact O-N 3.45Å; F48-I51 PolarHBondContact O-N 2.8Å; F48-K52 PolarHBondContact O-N 3.15Å
49	S	77.3	Confident	80.3	Confident	81 Å²	81	64.1 Å²	64.1	57%	0.566	32%	0.316	S	S	*	.	H	α-helix	trans	-60	-36.6	175	51.9	0	0	0	0	112.6	E47 A53	E47-S49 PolarHBondContact O-N 2.91Å; S49-A53 WeakPolarHBondContact O-CB 3.48Å; S49-A53 PolarHBondContact O-N 3.39Å
50	K	74.1	Confident	79.8	Confident	60 Å²	60	64.6 Å²	64.6	26%	0.261	32%	0.321	S	S	.	.	H	α-helix	trans	-74.3	-39	179.5	-64.9	-177.1	176.8	172.7	0	112.3	E47 F48 K52 A53 H54 N117	E47-K50 HydrophobicContact CB-CB 4.43Å; E47-K50 HydrophobicContact CB-CD 4.08Å; E47-K50 HydrophobicContact CB-CG 4.06Å; E47-K50 WeakPolarHBondContact O-CB 3.41Å; E47-K50 PolarHBondContact O-N 3.14Å; E47-K50 WeakPolarHBondContact OE2-CE 3.28Å; E47-K50 IonicContact OE2-NZ 3.8Å; E47-K50 PolarHBondContact OE2-NZ 3.46Å; F48-K50 VanDerWaalsContact C-N 3.27Å; F48-K50 PolarHBondContact O-N 3.45Å; K50-K52 VanDerWaalsContact C-N 3.32Å; K50-K52 PolarHBondContact O-N 2.92Å; K50-A53 PolarHBondContact O-N 2.97Å; K50-H54 PolarHBondContact O-N 3.14Å; K50-H54 VanDerWaalsContact O-N 3.08Å; K50-N117 HydrophobicContact CD-CB 4.37Å; K50-N117 WeakPolarHBondContact CD-OD1 3.21Å; K50-N117 VanDerWaalsContact CE-OD1 3.24Å; K50-N117 WeakPolarHBondContact CE-OD1 3.48Å; K50-N117 PolarHBondContact NZ-OD1 3.44Å
51	I	74.3	Confident	79.5	Confident	25 Å²	25	64.1 Å²	64.1	13%	0.128	32%	0.319	C	S	.	.	H	α-helix	trans	-56.1	-52.8	170.8	-66.7	166.1	0	0	0	109.2	M46 E47 F48 A53 H54 L55	M46-I51 HydrophobicContact CE-CD1 3.64Å; M46-I51 HydrophobicContact CE-CG1 3.17Å; M46-I51 HydrophobicContact CG-CD1 3.55Å; M46-I51 HydrophobicContact CG-CG1 4Å; M46-I51 HydrophobicContact SD-CD1 3.8Å; M46-I51 HydrophobicContact SD-CG1 3.5Å; M46-I51 VanDerWaalsContact SD-CG1 3.5Å; E47-I51 PolarHBondContact O-N 2.9Å; F48-I51 PolarHBondContact O-N 2.8Å; I51-A53 PolarHBondContact O-N 2.64Å; I51-H54 PolarHBondContact O-N 2.95Å; I51-L55 HydrophobicContact CG2-CD1 3.65Å; I51-L55 HydrophobicContact CG2-CG 4.13Å; I51-L55 VanDerWaalsContact O-CG 3.3Å; I51-L55 WeakPolarHBondContact O-CG 3.31Å; I51-L55 PolarHBondContact O-N 3.41Å
52	K	78.8	Confident	79.5	Confident	126 Å²	126	65.9 Å²	65.9	55%	0.548	33%	0.334	S	S	.	.	H	α-helix	trans	-56.3	-53	-179.2	-168.1	176	-179.4	-179.2	0	110.1	F48 K50 H54 L55 W56	F48-K52 PolarHBondContact O-N 3.15Å; K50-K52 VanDerWaalsContact C-N 3.32Å; K50-K52 PolarHBondContact O-N 2.92Å; K52-H54 VanDerWaalsContact C-N 3.32Å; K52-H54 PolarHBondContact O-N 3.45Å; K52-L55 PolarHBondContact O-N 3.43Å; K52-L55 VanDerWaalsContact O-N 3.14Å; K52-W56 PolarHBondContact O-N 3.45Å
53	A	74.8	Confident	79.5	Confident	59 Å²	59	66.6 Å²	66.6	49%	0.488	34%	0.338	S	S	.	.	H	α-helix	trans	-56.3	-40.5	-178.4	0	0	0	0	0	114.1	S49 K50 I51 W56	S49-A53 WeakPolarHBondContact O-CB 3.48Å; S49-A53 PolarHBondContact O-N 3.39Å; K50-A53 PolarHBondContact O-N 2.97Å; I51-A53 PolarHBondContact O-N 2.64Å; A53-W56 PolarHBondContact O-N 3.3Å
54	H	72.5	Confident	79.4	Confident	39 Å²	39	66.8 Å²	66.8	18%	0.181	34%	0.339	C	S	.	.	H	α-helix	trans	-79.2	-26.7	178.3	-82.2	-39.3	0	0	0	113.9	K50 I51 K52 W56 K57 V121	K50-H54 PolarHBondContact O-N 3.14Å; K50-H54 VanDerWaalsContact O-N 3.08Å; I51-H54 PolarHBondContact O-N 2.95Å; K52-H54 VanDerWaalsContact C-N 3.32Å; K52-H54 PolarHBondContact O-N 3.45Å; H54-W56 PolarHBondContact O-N 2.88Å; H54-K57 CarbonylContact O-C 3.39Å; H54-K57 VanDerWaalsContact O-C 3.22Å; H54-K57 PolarHBondContact O-N 2.85Å; H54-K57 VanDerWaalsContact O-N 3.08Å; H54-V121 HydrophobicContact CB-CB 4.41Å; H54-V121 HydrophobicContact CB-CG1 3.94Å; H54-V121 HydrophobicContact CB-CG2 4.17Å
55	L	73.8	Confident	79.6	Confident	98 Å²	98	68.7 Å²	68.7	51%	0.513	35%	0.349	S	S	.	.	H	α-helix	trans	-62.6	-29.2	168.6	-71.8	173.2	0	0	0	112.1	I51 K52 K57 L61	I51-L55 HydrophobicContact CG2-CD1 3.65Å; I51-L55 HydrophobicContact CG2-CG 4.13Å; I51-L55 VanDerWaalsContact O-CG 3.3Å; I51-L55 WeakPolarHBondContact O-CG 3.31Å; I51-L55 PolarHBondContact O-N 3.41Å; K52-L55 PolarHBondContact O-N 3.43Å; K52-L55 VanDerWaalsContact O-N 3.14Å; L55-K57 VanDerWaalsContact C-N 3.35Å; L55-L61 HydrophobicContact CD2-CD2 3.95Å
56	W	71.8	Confident	80	Confident	202 Å²	202	70.3 Å²	70.3	77%	0.765	36%	0.359	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78	-14.4	173.8	-76.9	90.9	0	0	0	114.1	K52 A53 H54	K52-W56 PolarHBondContact O-N 3.45Å; A53-W56 PolarHBondContact O-N 3.3Å; H54-W56 PolarHBondContact O-N 2.88Å
57	K	72.5	Confident	80.5	Confident	127 Å²	127	70.2 Å²	70.2	55%	0.552	36%	0.358	S	S	*	.	S	Bend	trans	-123.9	70.2	174.2	-67.6	-171.2	-179.6	-176.3	0	110.2	H54 L55 K59	H54-K57 CarbonylContact O-C 3.39Å; H54-K57 VanDerWaalsContact O-C 3.22Å; H54-K57 PolarHBondContact O-N 2.85Å; H54-K57 VanDerWaalsContact O-N 3.08Å; L55-K57 VanDerWaalsContact C-N 3.35Å; K57-K59 VanDerWaalsContact C-N 3.3Å; K57-K59 PolarHBondContact O-N 3.17Å
58	P	78.3	Confident	81.2	Confident	73 Å²	73	67.3 Å²	67.3	47%	0.474	35%	0.345	S	S	.	.	H	α-helix	trans	-74.1	-12.7	-161.5	29.4	-37.2	0	0	0	114.7	G60 L61 A62	P58-G60 PolarHBondContact O-N 3.19Å; P58-L61 PolarHBondContact O-N 3.15Å; P58-A62 WeakPolarHBondContact O-CB 3.36Å; P58-A62 PolarHBondContact O-N 3.12Å
59	K	81.9	Confident	82.1	Confident	168 Å²	168	61.6 Å²	61.6	73%	0.73	32%	0.319	S	S	*	.	H	α-helix	trans	-54.1	-52.5	-172.5	-66.8	-170.9	178.4	-174.9	0	112.3	K57 L61 A62 I63	K57-K59 VanDerWaalsContact C-N 3.3Å; K57-K59 PolarHBondContact O-N 3.17Å; K59-L61 PolarHBondContact O-N 2.91Å; K59-A62 PolarHBondContact O-N 2.72Å; K59-I63 WeakPolarHBondContact O-CD1 3.41Å; K59-I63 WeakPolarHBondContact O-CG1 3.39Å; K59-I63 PolarHBondContact O-N 2.99Å; K59-I63 VanDerWaalsContact O-N 3.07Å
60	G	79.4	Confident	82.9	Confident	10 Å²	10	59.2 Å²	59.2	10%	0.103	31%	0.308	C	S	.	.	H	α-helix	trans	-64.2	-42.2	179.9	0	0	0	0	0	112.9	P58 I63 A64 M122	P58-G60 PolarHBondContact O-N 3.19Å; G60-I63 PolarHBondContact O-N 3.24Å; G60-A64 PolarHBondContact O-N 3.49Å; G60-M122 VanDerWaalsContact O-CE 3.28Å; G60-M122 WeakPolarHBondContact O-CE 3.16Å
61	L	84.9	Confident	83.9	Confident	11 Å²	11	57.4 Å²	57.4	6%	0.058	30%	0.301	C	S	.	.	H	α-helix	trans	-64.2	-45.4	178.6	179.4	58	0	0	0	112.1	L55 P58 K59 A64 L65 V121 M122 C125	L55-L61 HydrophobicContact CD2-CD2 3.95Å; P58-L61 PolarHBondContact O-N 3.15Å; K59-L61 PolarHBondContact O-N 2.91Å; L61-A64 PolarHBondContact O-N 3.1Å; L61-L65 HydrophobicContact CD1-CD1 4.39Å; L61-L65 HydrophobicContact CD1-CG 4.35Å; L61-L65 HydrophobicContact CG-CD1 4.28Å; L61-L65 WeakPolarHBondContact O-CG 3.42Å; L61-L65 PolarHBondContact O-N 2.87Å; L61-V121 HydrophobicContact CD1-CG1 4.14Å; L61-V121 HydrophobicContact CD2-CG1 4.27Å; L61-M122 HydrophobicContact CD1-CG 4.21Å; L61-C125 HydrophobicContact CD1-CB 3.81Å
62	A	88.6	Confident	85	Confident	49 Å²	49	56.2 Å²	56.2	41%	0.405	29%	0.294	S	S	.	.	H	α-helix	trans	-62.2	-44.5	178.3	0	0	0	0	0	111.3	P58 K59 A64 L65 V66	P58-A62 WeakPolarHBondContact O-CB 3.36Å; P58-A62 PolarHBondContact O-N 3.12Å; K59-A62 PolarHBondContact O-N 2.72Å; A62-A64 VanDerWaalsContact C-N 3.31Å; A62-A64 PolarHBondContact O-N 2.74Å; A62-L65 PolarHBondContact O-N 3.37Å; A62-V66 WeakPolarHBondContact O-CG2 3.32Å; A62-V66 PolarHBondContact O-N 2.87Å
63	I	89	Confident	85.8	Confident	16 Å²	16	50.2 Å²	50.2	8%	0.082	27%	0.268	C	S	.	.	H	α-helix	trans	-61.6	-41.3	177.3	-66.3	159.1	0	0	0	110.8	K59 G60 V66 A67 L240 F244 L246	K59-I63 WeakPolarHBondContact O-CD1 3.41Å; K59-I63 WeakPolarHBondContact O-CG1 3.39Å; K59-I63 PolarHBondContact O-N 2.99Å; K59-I63 VanDerWaalsContact O-N 3.07Å; G60-I63 PolarHBondContact O-N 3.24Å; I63-V66 PolarHBondContact O-N 3.4Å; I63-A67 WeakPolarHBondContact O-CB 3.38Å; I63-A67 PolarHBondContact O-N 2.94Å; I63-L240 HydrophobicContact CG2-CD2 4.27Å; I63-L240 HydrophobicContact CG2-CG 4.36Å; I63-F244 HydrophobicContact CD1-CB 3.4Å; I63-F244 HydrophobicContact CD1-CD1 4.46Å; I63-F244 HydrophobicContact CD1-CD2 4.34Å; I63-F244 HydrophobicContact CD1-CG 3.85Å; I63-F244 HydrophobicContact CG1-CB 4.13Å; I63-F244 HydrophobicContact CG1-CD2 4.13Å; I63-F244 HydrophobicContact CG1-CG 4.06Å; I63-F244 HydrophobicContact CG2-CD2 4.26Å; I63-L246 HydrophobicContact CB-CD1 4.16Å; I63-L246 HydrophobicContact CD1-CD1 3.49Å; I63-L246 VanDerWaalsContact CD1-CD1 3.49Å; I63-L246 HydrophobicContact CD1-CG 4.08Å; I63-L246 HydrophobicContact CG1-CD1 4.42Å; I63-L246 HydrophobicContact CG2-CD1 3.86Å
64	A	86	Confident	86.9	Confident	4 Å²	4	51.4 Å²	51.4	3%	0.033	27%	0.266	C	S	.	.	H	α-helix	trans	-69.3	-37	175.6	0	0	0	0	0	113.8	G60 L61 A62 V66 A67 Q68 M122 V254	G60-A64 PolarHBondContact O-N 3.49Å; L61-A64 PolarHBondContact O-N 3.1Å; A62-A64 VanDerWaalsContact C-N 3.31Å; A62-A64 PolarHBondContact O-N 2.74Å; A64-V66 VanDerWaalsContact C-N 3.32Å; A64-A67 WeakPolarHBondContact O-CB 3.47Å; A64-A67 PolarHBondContact O-N 3.34Å; A64-Q68 VanDerWaalsContact O-CB 3.27Å; A64-Q68 WeakPolarHBondContact O-CB 3.43Å; A64-Q68 PolarHBondContact O-N 2.92Å; A64-M122 HydrophobicContact CB-CB 4.26Å; A64-M122 HydrophobicContact CB-CE 3.36Å; A64-M122 HydrophobicContact CB-CG 3.55Å; A64-M122 HydrophobicContact CB-SD 3.35Å; A64-M122 WeakPolarHBondContact CB-SD 3.32Å; A64-V254 HydrophobicContact CB-CG1 4.47Å; A64-V254 HydrophobicContact CB-CG2 4.34Å
65	L	91.3	Very high	88	Confident	41 Å²	41	50.2 Å²	50.2	22%	0.215	26%	0.261	C	S	.	.	H	α-helix	trans	-64.8	-39.7	174.8	-73.4	173.5	0	0	0	111.3	L61 A62 Q68 Y69	L61-L65 HydrophobicContact CD1-CD1 4.39Å; L61-L65 HydrophobicContact CD1-CG 4.35Å; L61-L65 HydrophobicContact CG-CD1 4.28Å; L61-L65 WeakPolarHBondContact O-CG 3.42Å; L61-L65 PolarHBondContact O-N 2.87Å; A62-L65 PolarHBondContact O-N 3.37Å; L65-Q68 PolarHBondContact O-N 3.2Å; L65-Y69 HydrophobicContact CD2-CD2 4.43Å; L65-Y69 HydrophobicContact CD2-CE2 4.31Å; L65-Y69 WeakPolarHBondContact O-CB 3.48Å; L65-Y69 PolarHBondContact O-N 3.3Å
66	V	93.1	Very high	89.1	Confident	91 Å²	91	45.5 Å²	45.5	55%	0.552	24%	0.237	S	C	*	.	H	α-helix	trans	-65.8	-39.8	173	172.4	0	0	0	0	111.1	A62 I63 A64 G70 L240	A62-V66 WeakPolarHBondContact O-CG2 3.32Å; A62-V66 PolarHBondContact O-N 2.87Å; I63-V66 PolarHBondContact O-N 3.4Å; A64-V66 VanDerWaalsContact C-N 3.32Å; V66-G70 WeakPolarHBondContact O-CA 3.46Å; V66-G70 PolarHBondContact O-N 3.22Å; V66-L240 HydrophobicContact CG1-CD2 4.38Å
67	A	91.8	Very high	90.3	Very high	0 Å²	0	38.1 Å²	38.1	0%	0	21%	0.21	C	C	.	.	I	π-helix	trans	-62.1	-50.9	174.1	0	0	0	0	0	110.9	I63 A64 I71 L240 V254 T258	I63-A67 WeakPolarHBondContact O-CB 3.38Å; I63-A67 PolarHBondContact O-N 2.94Å; A64-A67 WeakPolarHBondContact O-CB 3.47Å; A64-A67 PolarHBondContact O-N 3.34Å; A67-I71 HydrophobicContact CB-CD1 3.97Å; A67-I71 WeakPolarHBondContact O-CA 3.35Å; A67-I71 WeakPolarHBondContact O-CB 3.43Å; A67-I71 PolarHBondContact O-N 2.93Å; A67-L240 HydrophobicContact CB-CD2 3.91Å; A67-V254 HydrophobicContact CB-CG1 4.21Å; A67-T258 HydrophobicContact CB-CG2 4.09Å; A67-T258 VanDerWaalsContact CB-OG1 3.3Å; A67-T258 WeakPolarHBondContact CB-OG1 3.4Å
68	Q	94.3	Very high	91.4	Very high	2 Å²	2	35.2 Å²	35.2	1%	0.009	20%	0.203	C	C	.	.	I	π-helix	trans	-63	-48.4	-176.5	-171.1	64.3	25.3	0	0	112.4	A64 L65 M72 P73 S99 E257 Q261	A64-Q68 VanDerWaalsContact O-CB 3.27Å; A64-Q68 WeakPolarHBondContact O-CB 3.43Å; A64-Q68 PolarHBondContact O-N 2.92Å; L65-Q68 PolarHBondContact O-N 3.2Å; Q68-M72 WeakPolarHBondContact O-CB 3.34Å; Q68-P73 WeakPolarHBondContact O-CD 3.4Å; Q68-S99 PolarHBondContact NE2-O 2.86Å; Q68-E257 PolarHBondContact OE1-O 2.85Å; Q68-Q261 VanDerWaalsContact NE2-CD 3.33Å
69	Y	95.1	Very high	92.3	Very high	11 Å²	11	32.4 Å²	32.4	4%	0.043	18%	0.184	C	C	.	.	I	π-helix	trans	-98.4	-7.5	-174.2	-72.7	-59.5	0	0	0	114.3	L65 P73 S126 C129 A130 M133 L137	L65-Y69 HydrophobicContact CD2-CD2 4.43Å; L65-Y69 HydrophobicContact CD2-CE2 4.31Å; L65-Y69 WeakPolarHBondContact O-CB 3.48Å; L65-Y69 PolarHBondContact O-N 3.3Å; Y69-P73 WeakPolarHBondContact O-CG 3.33Å; Y69-S126 PolarHBondContact OH-O 3.41Å; Y69-C129 HydrophobicContact CE2-CB 3.83Å; Y69-A130 WeakPolarHBondContact OH-CA 3.43Å; Y69-A130 VanDerWaalsContact OH-CB 3.24Å; Y69-A130 WeakPolarHBondContact OH-CB 3.42Å; Y69-A130 PolarHBondContact OH-N 3.05Å; Y69-A130 VanDerWaalsContact OH-N 3.15Å; Y69-M133 HydrophobicContact CD1-CB 3.69Å; Y69-M133 HydrophobicContact CD1-CG 4.42Å; Y69-M133 HydrophobicContact CD2-CB 4.13Å; Y69-M133 HydrophobicContact CD2-CE 4.48Å; Y69-M133 HydrophobicContact CD2-CG 4Å; Y69-M133 HydrophobicContact CE1-CB 3.67Å; Y69-M133 HydrophobicContact CE2-CB 4.11Å; Y69-M133 HydrophobicContact CE2-CG 4.12Å; Y69-M133 HydrophobicContact CG-CB 3.93Å; Y69-M133 HydrophobicContact CG-CE 4.06Å; Y69-M133 HydrophobicContact CG-CG 4.15Å; Y69-L137 HydrophobicContact CD1-CD1 3.49Å; Y69-L137 VanDerWaalsContact CD1-CD1 3.49Å; Y69-L137 HydrophobicContact CE1-CD1 4.43Å; Y69-L137 HydrophobicContact CG-CD1 4.11Å
70	G	95	Very high	92.9	Very high	31 Å²	31	24.7 Å²	24.7	32%	0.32	15%	0.152	S	C	.	.	I	π-helix	trans	-98.5	-60.9	172.4	0	0	0	0	0	111.6	V66 L74	V66-G70 WeakPolarHBondContact O-CA 3.46Å; V66-G70 PolarHBondContact O-N 3.22Å; G70-L74 WeakPolarHBondContact O-CB 3.21Å; G70-L74 PolarHBondContact O-N 3.26Å
71	I	95.8	Very high	93.5	Very high	22 Å²	22	29.6 Å²	29.6	11%	0.113	17%	0.171	C	C	.	.	I	π-helix	trans	-67.4	-49.5	-171.7	-61.9	172.1	0	0	0	111	A67 L74 T75 L236 L240 T258	A67-I71 HydrophobicContact CB-CD1 3.97Å; A67-I71 WeakPolarHBondContact O-CA 3.35Å; A67-I71 WeakPolarHBondContact O-CB 3.43Å; A67-I71 PolarHBondContact O-N 2.93Å; I71-L74 PolarHBondContact O-N 3.45Å; I71-T75 VanDerWaalsContact O-CB 3.29Å; I71-T75 WeakPolarHBondContact O-CB 3.33Å; I71-T75 PolarHBondContact O-N 3.07Å; I71-T75 PolarHBondContact O-OG1 3.48Å; I71-L236 HydrophobicContact CD1-CB 3.89Å; I71-L236 HydrophobicContact CG2-CB 3.77Å; I71-L236 HydrophobicContact CG2-CD1 3.79Å; I71-L236 HydrophobicContact CG2-CG 4.41Å; I71-L240 HydrophobicContact CD1-CB 4.21Å; I71-L240 HydrophobicContact CD1-CD2 3.92Å; I71-T258 HydrophobicContact CB-CG2 4.39Å; I71-T258 HydrophobicContact CD1-CG2 4.45Å; I71-T258 HydrophobicContact CG2-CG2 4.47Å
72	M	95.8	Very high	94	Very high	0 Å²	0	33.7 Å²	33.7	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-69.7	-46.4	-170.4	-81.5	-70.7	-166.7	0	0	114.5	Q68 L74 T75 A76 G97 M229 T258 G259 Y289	Q68-M72 WeakPolarHBondContact O-CB 3.34Å; M72-L74 VanDerWaalsContact C-N 3.32Å; M72-L74 PolarHBondContact O-N 2.94Å; M72-T75 PolarHBondContact O-N 3.47Å; M72-A76 PolarHBondContact O-N 2.81Å; M72-G97 WeakPolarHBondContact CB-O 3.31Å; M72-M229 WeakPolarHBondContact CE-O 3.44Å; M72-T258 WeakPolarHBondContact CE-O 3.49Å; M72-T258 HydrophobicContact CG-CG2 4.1Å; M72-T258 WeakPolarHBondContact CG-O 3.47Å; M72-G259 VanDerWaalsContact CE-CA 3.44Å; M72-Y289 WeakPolarHBondContact CE-OH 3.39Å
73	P	96.8	Very high	94.3	Very high	0 Å²	0	33.7 Å²	33.7	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-60.4	-41.6	172.5	-26.4	36.2	0	0	0	112.5	Q68 Y69 T75 A76 F77 G97 L137 Y141	Q68-P73 WeakPolarHBondContact O-CD 3.4Å; Y69-P73 WeakPolarHBondContact O-CG 3.33Å; P73-T75 VanDerWaalsContact C-N 3.35Å; P73-A76 PolarHBondContact O-N 2.81Å; P73-F77 WeakPolarHBondContact O-CB 3.35Å; P73-F77 PolarHBondContact O-N 2.83Å; P73-G97 WeakPolarHBondContact CD-O 3.38Å; P73-G97 WeakPolarHBondContact CG-O 3.32Å; P73-L137 HydrophobicContact CB-CD1 4.46Å; P73-L137 HydrophobicContact CG-CD1 3.79Å; P73-Y141 HydrophobicContact CB-CD2 4.12Å; P73-Y141 HydrophobicContact CB-CE2 3.61Å
74	L	96.8	Very high	94.4	Very high	85 Å²	85	41.1 Å²	41.1	45%	0.445	22%	0.221	S	C	.	.	H	α-helix	trans	-63.3	-43.5	177.4	-178.4	62.4	0	0	0	111.1	G70 I71 M72 F77 V78 Y141	G70-L74 WeakPolarHBondContact O-CB 3.21Å; G70-L74 PolarHBondContact O-N 3.26Å; I71-L74 PolarHBondContact O-N 3.45Å; M72-L74 VanDerWaalsContact C-N 3.32Å; M72-L74 PolarHBondContact O-N 2.94Å; L74-F77 PolarHBondContact O-N 3.24Å; L74-V78 HydrophobicContact CD1-CG2 4.06Å; L74-V78 HydrophobicContact CG-CG2 4.31Å; L74-V78 WeakPolarHBondContact O-CB 3.48Å; L74-V78 VanDerWaalsContact O-CG2 3.28Å; L74-V78 WeakPolarHBondContact O-CG2 3.33Å; L74-V78 PolarHBondContact O-N 3.42Å; L74-Y141 HydrophobicContact CD1-CE1 4.17Å
75	T	97.1	Very high	94.5	Very high	13 Å²	13	41.5 Å²	41.5	8%	0.08	22%	0.223	C	C	.	.	H	α-helix	trans	-60.6	-47.1	177	-60	0	0	0	0	110.6	I71 M72 P73 F77 V78 L79 M229 I232	I71-T75 VanDerWaalsContact O-CB 3.29Å; I71-T75 WeakPolarHBondContact O-CB 3.33Å; I71-T75 PolarHBondContact O-N 3.07Å; I71-T75 PolarHBondContact O-OG1 3.48Å; M72-T75 PolarHBondContact O-N 3.47Å; P73-T75 VanDerWaalsContact C-N 3.35Å; T75-F77 VanDerWaalsContact C-N 3.35Å; T75-F77 PolarHBondContact O-N 3.49Å; T75-V78 PolarHBondContact O-N 3.18Å; T75-L79 HydrophobicContact CG2-CD1 3.83Å; T75-L79 HydrophobicContact CG2-CG 4.34Å; T75-L79 WeakPolarHBondContact O-CB 3.28Å; T75-L79 VanDerWaalsContact O-CG 3.28Å; T75-L79 WeakPolarHBondContact O-CG 3.41Å; T75-L79 PolarHBondContact O-N 3.08Å; T75-M229 HydrophobicContact CG2-CG 4.32Å; T75-I232 HydrophobicContact CG2-CB 3.9Å; T75-I232 HydrophobicContact CG2-CD1 3.79Å; T75-I232 HydrophobicContact CG2-CG1 4.46Å; T75-I232 HydrophobicContact CG2-CG2 3.66Å; T75-I232 WeakPolarHBondContact OG1-CG2 3.15Å
76	A	96.7	Very high	94.4	Very high	0 Å²	0	44.7 Å²	44.7	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-58.9	-46.1	176.4	0	0	0	0	0	111.8	M72 P73 G80 I93 L94 M229	M72-A76 PolarHBondContact O-N 2.81Å; P73-A76 PolarHBondContact O-N 2.81Å; A76-G80 PolarHBondContact O-N 3.49Å; A76-I93 HydrophobicContact CB-CG1 4.45Å; A76-I93 WeakPolarHBondContact CB-O 3.14Å; A76-I93 WeakPolarHBondContact O-CD1 3.15Å; A76-L94 HydrophobicContact CB-CD1 4.23Å; A76-M229 HydrophobicContact CB-CE 3.6Å; A76-M229 HydrophobicContact CB-SD 4.22Å
77	F	96.4	Very high	94.2	Very high	46 Å²	46	43.9 Å²	43.9	20%	0.202	23%	0.232	C	C	.	.	H	α-helix	trans	-64	-47.2	179.1	178.2	-102.5	0	0	0	112.6	P73 L74 T75 G80 K81 L94 Y141 I145	P73-F77 WeakPolarHBondContact O-CB 3.35Å; P73-F77 PolarHBondContact O-N 2.83Å; L74-F77 PolarHBondContact O-N 3.24Å; T75-F77 VanDerWaalsContact C-N 3.35Å; T75-F77 PolarHBondContact O-N 3.49Å; F77-G80 PolarHBondContact O-N 2.93Å; F77-K81 HydrophobicContact CE1-CG 4.33Å; F77-K81 HydrophobicContact CZ-CG 4.21Å; F77-K81 PolarHBondContact O-N 3.48Å; F77-L94 HydrophobicContact CB-CD1 4.44Å; F77-Y141 HydrophobicContact CB-CD1 3.5Å; F77-Y141 VanDerWaalsContact CB-CD1 3.5Å; F77-Y141 HydrophobicContact CB-CE1 3.81Å; F77-Y141 HydrophobicContact CB-CG 4.23Å; F77-Y141 AromaticContact CD1-CD1 3.84Å; F77-Y141 HydrophobicContact CD1-CD1 3.84Å; F77-Y141 HydrophobicContact CD1-CE1 4.03Å; F77-Y141 AromaticContact CD2-CD1 3.63Å; F77-Y141 HydrophobicContact CD2-CD1 3.63Å; F77-Y141 HydrophobicContact CD2-CG 4.28Å; F77-Y141 HydrophobicContact CE1-CD1 4.47Å; F77-Y141 HydrophobicContact CE2-CD1 4.28Å; F77-Y141 WeakPolarHBondContact CE2-O 3.35Å; F77-Y141 AromaticContact CG-CD1 3.36Å; F77-Y141 HydrophobicContact CG-CD1 3.36Å; F77-Y141 AromaticContact CG-CE1 3.89Å; F77-Y141 HydrophobicContact CG-CE1 3.89Å; F77-Y141 HydrophobicContact CG-CG 4.31Å; F77-I145 HydrophobicContact CD2-CD1 4.35Å; F77-I145 HydrophobicContact CD2-CG1 4.1Å; F77-I145 HydrophobicContact CE2-CG1 3.98Å
78	V	96.8	Very high	94	Very high	67 Å²	67	46.3 Å²	46.3	41%	0.406	25%	0.245	S	C	.	.	H	α-helix	trans	-63.5	-46.1	179.7	170.2	0	0	0	0	110.6	L74 T75 G80 K81 V82	L74-V78 HydrophobicContact CD1-CG2 4.06Å; L74-V78 HydrophobicContact CG-CG2 4.31Å; L74-V78 WeakPolarHBondContact O-CB 3.48Å; L74-V78 VanDerWaalsContact O-CG2 3.28Å; L74-V78 WeakPolarHBondContact O-CG2 3.33Å; L74-V78 PolarHBondContact O-N 3.42Å; T75-V78 PolarHBondContact O-N 3.18Å; V78-G80 VanDerWaalsContact C-N 3.31Å; V78-G80 PolarHBondContact O-N 3.33Å; V78-K81 PolarHBondContact O-N 3.18Å; V78-K81 VanDerWaalsContact O-N 3.16Å; V78-V82 HydrophobicContact CG1-CG2 3.98Å; V78-V82 WeakPolarHBondContact O-CB 3.42Å; V78-V82 VanDerWaalsContact O-CG2 3.28Å; V78-V82 WeakPolarHBondContact O-CG2 3.49Å; V78-V82 PolarHBondContact O-N 3.13Å
79	L	96.2	Very high	93.8	Very high	14 Å²	14	46.9 Å²	46.9	7%	0.073	25%	0.248	C	C	.	.	H	α-helix	trans	-62.7	-39.3	176.8	-70	175	0	0	0	111.6	T75 K81 V82 F83 T225 L228 M229 I232	T75-L79 HydrophobicContact CG2-CD1 3.83Å; T75-L79 HydrophobicContact CG2-CG 4.34Å; T75-L79 WeakPolarHBondContact O-CB 3.28Å; T75-L79 VanDerWaalsContact O-CG 3.28Å; T75-L79 WeakPolarHBondContact O-CG 3.41Å; T75-L79 PolarHBondContact O-N 3.08Å; L79-K81 VanDerWaalsContact C-N 3.29Å; L79-K81 PolarHBondContact O-N 3.41Å; L79-V82 PolarHBondContact O-N 2.92Å; L79-F83 HydrophobicContact CB-CD2 4.36Å; L79-F83 HydrophobicContact CD2-CD2 4.43Å; L79-F83 HydrophobicContact CD2-CE2 3.87Å; L79-F83 HydrophobicContact CD2-CZ 4.4Å; L79-F83 WeakPolarHBondContact O-CB 3.28Å; L79-F83 PolarHBondContact O-N 3.42Å; L79-T225 HydrophobicContact CB-CG2 4.1Å; L79-T225 HydrophobicContact CD1-CG2 4.12Å; L79-L228 HydrophobicContact CD1-CB 3.99Å; L79-L228 HydrophobicContact CD2-CB 4.35Å; L79-L228 HydrophobicContact CD2-CD1 4.12Å; L79-M229 HydrophobicContact CD1-CB 4.46Å; L79-M229 HydrophobicContact CD1-CG 3.51Å; L79-I232 HydrophobicContact CD1-CD1 4.3Å; L79-I232 HydrophobicContact CD2-CD1 4.43Å
80	G	94.1	Very high	93.7	Very high	6 Å²	6	46.6 Å²	46.6	6%	0.062	25%	0.248	C	C	.	.	H	α-helix	trans	-58.3	-39.6	173.8	0	0	0	0	0	113.1	A76 F77 V78 Q84 L85	A76-G80 PolarHBondContact O-N 3.49Å; F77-G80 PolarHBondContact O-N 2.93Å; V78-G80 VanDerWaalsContact C-N 3.31Å; V78-G80 PolarHBondContact O-N 3.33Å; G80-Q84 PolarHBondContact O-N 2.82Å; G80-L85 PolarHBondContact O-N 2.7Å
81	K	93.2	Very high	93.5	Very high	112 Å²	112	45.1 Å²	45.1	49%	0.487	23%	0.233	S	C	.	.	H	α-helix	trans	-75.1	-45.5	176.3	-73.2	-67.1	-171.7	-178.9	0	113.2	F77 V78 L79 F83 Q84 G144	F77-K81 HydrophobicContact CE1-CG 4.33Å; F77-K81 HydrophobicContact CZ-CG 4.21Å; F77-K81 PolarHBondContact O-N 3.48Å; V78-K81 PolarHBondContact O-N 3.18Å; V78-K81 VanDerWaalsContact O-N 3.16Å; L79-K81 VanDerWaalsContact C-N 3.29Å; L79-K81 PolarHBondContact O-N 3.41Å; K81-F83 VanDerWaalsContact C-N 3.34Å; K81-F83 PolarHBondContact O-N 3.29Å; K81-Q84 PolarHBondContact O-N 2.82Å; K81-Q84 VanDerWaalsContact O-N 3.13Å; K81-G144 WeakPolarHBondContact CE-O 3.48Å; K81-G144 PolarHBondContact NZ-O 3.13Å
82	V	95.3	Very high	93.3	Very high	97 Å²	97	44.1 Å²	44.1	59%	0.588	23%	0.227	S	C	*	.	H	α-helix	trans	-63.5	-41.9	-178.1	168.5	0	0	0	0	111	V78 L79 Q84	V78-V82 HydrophobicContact CG1-CG2 3.98Å; V78-V82 WeakPolarHBondContact O-CB 3.42Å; V78-V82 VanDerWaalsContact O-CG2 3.28Å; V78-V82 WeakPolarHBondContact O-CG2 3.49Å; V78-V82 PolarHBondContact O-N 3.13Å; L79-V82 PolarHBondContact O-N 2.92Å; V82-Q84 VanDerWaalsContact C-N 3.27Å; V82-Q84 PolarHBondContact O-N 3.16Å
83	F	93.4	Very high	93.3	Very high	50 Å²	50	44.1 Å²	44.1	22%	0.219	23%	0.228	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.1	4.6	176.9	-65.5	-38.6	0	0	0	114.1	L79 K81 L85 L221 A224 T225 L228	L79-F83 HydrophobicContact CB-CD2 4.36Å; L79-F83 HydrophobicContact CD2-CD2 4.43Å; L79-F83 HydrophobicContact CD2-CE2 3.87Å; L79-F83 HydrophobicContact CD2-CZ 4.4Å; L79-F83 WeakPolarHBondContact O-CB 3.28Å; L79-F83 PolarHBondContact O-N 3.42Å; K81-F83 VanDerWaalsContact C-N 3.34Å; K81-F83 PolarHBondContact O-N 3.29Å; F83-L85 HydrophobicContact CB-CD2 3.99Å; F83-L85 HydrophobicContact CB-CG 4.09Å; F83-L85 PolarHBondContact O-N 2.66Å; F83-L221 HydrophobicContact CB-CD2 4.15Å; F83-L221 HydrophobicContact CD1-CD2 4.23Å; F83-L221 HydrophobicContact CG-CD2 4.32Å; F83-A224 HydrophobicContact CE2-CB 4.16Å; F83-A224 HydrophobicContact CZ-CB 4.08Å; F83-T225 WeakPolarHBondContact CD2-OG1 3.29Å; F83-L228 HydrophobicContact CE2-CD1 3.91Å; F83-L228 HydrophobicContact CZ-CD1 3.6Å
84	Q	91.3	Very high	93.2	Very high	171 Å²	171	44.1 Å²	44.1	80%	0.799	23%	0.228	S	C	*	.	T	Hydrogen-bonded Turn	trans	49.4	43.5	179.2	-59.3	-177.5	-10.4	0	0	112.3	G80 K81 V82	G80-Q84 PolarHBondContact O-N 2.82Å; K81-Q84 PolarHBondContact O-N 2.82Å; K81-Q84 VanDerWaalsContact O-N 3.13Å; V82-Q84 VanDerWaalsContact C-N 3.27Å; V82-Q84 PolarHBondContact O-N 3.16Å
85	L	88.9	Confident	93.1	Very high	13 Å²	13	40.1 Å²	40.1	7%	0.068	21%	0.206	C	C	.	.			trans	-65	147.3	180	-62.6	-172.8	0	0	0	110.3	G80 F83 E89 A90 I93 L221 L222	G80-L85 PolarHBondContact O-N 2.7Å; F83-L85 HydrophobicContact CB-CD2 3.99Å; F83-L85 HydrophobicContact CB-CG 4.09Å; F83-L85 PolarHBondContact O-N 2.66Å; L85-E89 HydrophobicContact CB-CB 3.93Å; L85-E89 HydrophobicContact CD1-CB 4.32Å; L85-A90 HydrophobicContact CB-CB 4.35Å; L85-I93 HydrophobicContact CD1-CD1 3.56Å; L85-I93 HydrophobicContact CD1-CG1 4.45Å; L85-I93 HydrophobicContact CD1-CG2 4.42Å; L85-L221 HydrophobicContact CD2-CB 3.83Å; L85-L221 HydrophobicContact CD2-CD1 4.28Å; L85-L222 HydrophobicContact CD1-CD2 4.44Å
86	N	89	Confident	93	Very high	107 Å²	107	39.5 Å²	39.5	57%	0.572	20%	0.203	S	C	*	.			trans	-63.6	157.4	173.9	-61.5	-63.2	0	0	0	110.1	I88 E89 A90	N86-I88 PolarHBondContact O-N 2.95Å; N86-E89 HydrophobicContact CB-CG 4.4Å; N86-E89 WeakPolarHBondContact CB-OE2 3.5Å; N86-E89 PolarHBondContact N-OE2 3.04Å; N86-E89 PolarHBondContact ND2-OE2 2.87Å; N86-E89 WeakPolarHBondContact O-CB 3.46Å; N86-E89 PolarHBondContact O-N 3.42Å; N86-A90 PolarHBondContact O-N 3.42Å
87	N	88.7	Confident	93	Very high	74 Å²	74	39.5 Å²	39.5	40%	0.396	20%	0.203	S	C	.	.	H	α-helix	trans	-57.6	-33.4	-172.6	-62.3	-16.2	0	0	0	113.9	L91 I145 Y146	N87-L91 VanDerWaalsContact O-CB 3.22Å; N87-L91 WeakPolarHBondContact O-CB 3.5Å; N87-L91 PolarHBondContact O-N 3.13Å; N87-I145 HydrophobicContact CB-CG2 3.96Å; N87-I145 PolarHBondContact OD1-O 3.44Å; N87-Y146 HydrophobicContact CB-CD1 3.84Å; N87-Y146 HydrophobicContact CB-CE1 3.3Å; N87-Y146 HydrophobicContact CB-CE2 4.32Å; N87-Y146 PolarHBondContact O-OH 3.31Å
88	I	87.4	Confident	92.9	Very high	52 Å²	52	37.3 Å²	37.3	27%	0.267	19%	0.193	S	C	.	.	H	α-helix	trans	-72.2	-41.6	176.7	-51.4	-48.4	0	0	0	111.3	N86 L91 A92 Y146 V278 I279 L282	N86-I88 PolarHBondContact O-N 2.95Å; I88-L91 WeakPolarHBondContact O-CB 3.35Å; I88-L91 PolarHBondContact O-N 3.47Å; I88-A92 PolarHBondContact O-N 3.44Å; I88-Y146 WeakPolarHBondContact CD1-OH 3.48Å; I88-V278 HydrophobicContact CD1-CG1 3.67Å; I88-V278 HydrophobicContact CG1-CG1 4.44Å; I88-V278 HydrophobicContact CG2-CG1 4.37Å; I88-V278 WeakPolarHBondContact CG2-O 3.19Å; I88-I279 HydrophobicContact CG2-CD1 4.27Å; I88-L282 HydrophobicContact CB-CD1 4.18Å; I88-L282 HydrophobicContact CG2-CD1 3.48Å; I88-L282 VanDerWaalsContact CG2-CD1 3.48Å
89	E	90.2	Very high	92.8	Very high	13 Å²	13	34.1 Å²	34.1	6%	0.061	17%	0.174	C	C	.	.	H	α-helix	trans	-64.6	-47.7	177.4	-66.6	171.9	137.8	0	0	110.5	L85 N86 L91 A92 I93 L222 L282	L85-E89 HydrophobicContact CB-CB 3.93Å; L85-E89 HydrophobicContact CD1-CB 4.32Å; N86-E89 HydrophobicContact CB-CG 4.4Å; N86-E89 WeakPolarHBondContact CB-OE2 3.5Å; N86-E89 PolarHBondContact N-OE2 3.04Å; N86-E89 PolarHBondContact ND2-OE2 2.87Å; N86-E89 WeakPolarHBondContact O-CB 3.46Å; N86-E89 PolarHBondContact O-N 3.42Å; E89-L91 VanDerWaalsContact C-N 3.27Å; E89-L91 PolarHBondContact O-N 3.49Å; E89-A92 PolarHBondContact O-N 3.31Å; E89-A92 VanDerWaalsContact O-N 3.12Å; E89-I93 WeakPolarHBondContact O-CG2 3.43Å; E89-I93 PolarHBondContact O-N 2.94Å; E89-L222 HydrophobicContact CB-CD2 4.34Å; E89-L282 HydrophobicContact CG-CD1 4.01Å; E89-L282 HydrophobicContact CG-CD2 4.05Å
90	A	92.2	Very high	92.7	Very high	6 Å²	6	33.4 Å²	33.4	5%	0.05	17%	0.17	C	C	.	.	H	α-helix	trans	-58	-39.9	175.1	0	0	0	0	0	111.7	L85 N86 I93 L94 I145	L85-A90 HydrophobicContact CB-CB 4.35Å; N86-A90 PolarHBondContact O-N 3.42Å; A90-I93 WeakPolarHBondContact O-CG1 3.21Å; A90-L94 WeakPolarHBondContact O-CB 3.3Å; A90-L94 PolarHBondContact O-N 3.41Å; A90-I145 HydrophobicContact CB-CD1 3.96Å; A90-I145 HydrophobicContact CB-CG1 4.33Å; A90-I145 HydrophobicContact CB-CG2 4.02Å
91	L	91.7	Very high	92.5	Very high	0 Å²	0	33.1 Å²	33.1	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-65.9	-43.1	174.8	178.8	64.1	0	0	0	112	N87 I88 E89 L94 V95 L138 T142 V154 F274	N87-L91 VanDerWaalsContact O-CB 3.22Å; N87-L91 WeakPolarHBondContact O-CB 3.5Å; N87-L91 PolarHBondContact O-N 3.13Å; I88-L91 WeakPolarHBondContact O-CB 3.35Å; I88-L91 PolarHBondContact O-N 3.47Å; E89-L91 VanDerWaalsContact C-N 3.27Å; E89-L91 PolarHBondContact O-N 3.49Å; L91-L94 PolarHBondContact O-N 3.42Å; L91-V95 HydrophobicContact CD1-CG2 4.4Å; L91-V95 VanDerWaalsContact O-CG2 3.29Å; L91-V95 WeakPolarHBondContact O-CG2 3.27Å; L91-V95 PolarHBondContact O-N 3.38Å; L91-L138 HydrophobicContact CD1-CD2 4.34Å; L91-T142 HydrophobicContact CD1-CG2 3.89Å; L91-V154 HydrophobicContact CD1-CG2 4.08Å; L91-V154 HydrophobicContact CD2-CG2 4.49Å; L91-F274 HydrophobicContact CD1-CZ 4.42Å; L91-F274 HydrophobicContact CD2-CD1 4.31Å; L91-F274 HydrophobicContact CD2-CE1 3.65Å; L91-F274 HydrophobicContact CD2-CZ 4.22Å; L91-F274 HydrophobicContact CG-CE1 4.28Å; L91-F274 HydrophobicContact CG-CZ 4.37Å
92	A	92.5	Very high	92.2	Very high	0 Å²	0	28 Å²	28	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-63.4	-44.8	-179.8	0	0	0	0	0	112.2	I88 E89 L94 V95 C96 L270 L282	I88-A92 PolarHBondContact O-N 3.44Å; E89-A92 PolarHBondContact O-N 3.31Å; E89-A92 VanDerWaalsContact O-N 3.12Å; A92-L94 VanDerWaalsContact C-N 3.31Å; A92-L94 PolarHBondContact O-N 3.1Å; A92-V95 PolarHBondContact O-N 2.89Å; A92-C96 PolarHBondContact O-N 2.91Å; A92-L270 HydrophobicContact CB-CD1 4.38Å; A92-L270 HydrophobicContact CB-CD2 4.23Å; A92-L282 HydrophobicContact CB-CB 3.94Å; A92-L282 HydrophobicContact CB-CD1 4.33Å
93	I	94.8	Very high	91.7	Very high	1 Å²	1	25.7 Å²	25.7	1%	0.005	13%	0.13	C	C	.	.	H	α-helix	trans	-68.3	-33.1	176	70.4	171	0	0	0	111.7	A76 L85 E89 A90 C96 G97 L222 T225 M229 F285	A76-I93 HydrophobicContact CB-CG1 4.45Å; A76-I93 WeakPolarHBondContact CB-O 3.14Å; A76-I93 WeakPolarHBondContact O-CD1 3.15Å; L85-I93 HydrophobicContact CD1-CD1 3.56Å; L85-I93 HydrophobicContact CD1-CG1 4.45Å; L85-I93 HydrophobicContact CD1-CG2 4.42Å; E89-I93 WeakPolarHBondContact O-CG2 3.43Å; E89-I93 PolarHBondContact O-N 2.94Å; A90-I93 WeakPolarHBondContact O-CG1 3.21Å; I93-C96 WeakPolarHBondContact O-CB 3.28Å; I93-C96 PolarHBondContact O-N 2.84Å; I93-G97 PolarHBondContact O-N 3.3Å; I93-L222 HydrophobicContact CG2-CD2 4.3Å; I93-T225 HydrophobicContact CB-CG2 4.32Å; I93-T225 HydrophobicContact CD1-CG2 3.76Å; I93-T225 HydrophobicContact CG2-CG2 4.01Å; I93-M229 HydrophobicContact CB-SD 4.12Å; I93-F285 HydrophobicContact CB-CE1 4.03Å; I93-F285 HydrophobicContact CB-CZ 3.95Å; I93-F285 HydrophobicContact CG2-CD1 4.13Å; I93-F285 HydrophobicContact CG2-CD2 3.95Å; I93-F285 HydrophobicContact CG2-CE1 3.71Å; I93-F285 HydrophobicContact CG2-CE2 3.48Å; I93-F285 VanDerWaalsContact CG2-CE2 3.48Å; I93-F285 HydrophobicContact CG2-CG 4.25Å; I93-F285 HydrophobicContact CG2-CZ 3.35Å
94	L	95.3	Very high	91.5	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-69.2	-41	177.5	-176.7	67.8	0	0	0	111.5	A76 F77 A90 L91 A92 C96 G97 C98 L138 Y141 T142 I145	A76-L94 HydrophobicContact CB-CD1 4.23Å; F77-L94 HydrophobicContact CB-CD1 4.44Å; A90-L94 WeakPolarHBondContact O-CB 3.3Å; A90-L94 PolarHBondContact O-N 3.41Å; L91-L94 PolarHBondContact O-N 3.42Å; A92-L94 VanDerWaalsContact C-N 3.31Å; A92-L94 PolarHBondContact O-N 3.1Å; L94-C96 PolarHBondContact O-N 2.82Å; L94-G97 PolarHBondContact O-N 2.97Å; L94-G97 VanDerWaalsContact O-N 3.16Å; L94-C98 WeakPolarHBondContact O-CB 3.33Å; L94-C98 PolarHBondContact O-N 2.96Å; L94-C98 PolarHBondContact O-SG 2.88Å; L94-L138 HydrophobicContact CB-CD2 4.43Å; L94-L138 HydrophobicContact CD2-CD2 3.82Å; L94-L138 HydrophobicContact CG-CD2 3.81Å; L94-Y141 HydrophobicContact CD1-CD2 4.17Å; L94-Y141 HydrophobicContact CD1-CG 4.08Å; L94-T142 HydrophobicContact CD2-CG2 4.01Å; L94-I145 HydrophobicContact CD2-CD1 3.83Å
95	V	94.5	Very high	91.5	Very high	0 Å²	0	17.7 Å²	17.7	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-57.2	-39.2	171	170.2	0	0	0	0	110.5	L91 A92 S99 M134 L138 I269 L270 F274	L91-V95 HydrophobicContact CD1-CG2 4.4Å; L91-V95 VanDerWaalsContact O-CG2 3.29Å; L91-V95 WeakPolarHBondContact O-CG2 3.27Å; L91-V95 PolarHBondContact O-N 3.38Å; A92-V95 PolarHBondContact O-N 2.89Å; V95-S99 PolarHBondContact O-N 3.31Å; V95-S99 PolarHBondContact O-OG 3.48Å; V95-M134 HydrophobicContact CB-CE 4.37Å; V95-M134 HydrophobicContact CG1-CE 3.59Å; V95-M134 WeakPolarHBondContact O-CE 3.43Å; V95-L138 HydrophobicContact CG2-CD1 4.24Å; V95-L138 HydrophobicContact CG2-CD2 3.85Å; V95-I269 HydrophobicContact CG1-CB 4.37Å; V95-I269 HydrophobicContact CG1-CG2 3.88Å; V95-L270 HydrophobicContact CB-CD2 3.97Å; V95-L270 HydrophobicContact CG1-CD2 3.89Å; V95-L270 HydrophobicContact CG1-CG 4.01Å; V95-L270 HydrophobicContact CG2-CD2 4.1Å; V95-F274 HydrophobicContact CG2-CE2 4.04Å; V95-F274 HydrophobicContact CG2-CZ 4.05Å
96	C	95.1	Very high	91.6	Very high	0 Å²	0	17.9 Å²	17.9	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-65.9	-46.2	174.3	-163.7	0	0	0	0	112.3	A92 I93 L94 C98 S99 C266 F285	A92-C96 PolarHBondContact O-N 2.91Å; I93-C96 WeakPolarHBondContact O-CB 3.28Å; I93-C96 PolarHBondContact O-N 2.84Å; L94-C96 PolarHBondContact O-N 2.82Å; C96-C98 VanDerWaalsContact C-N 3.33Å; C96-C98 PolarHBondContact O-N 3.42Å; C96-S99 VanDerWaalsContact O-CB 3.26Å; C96-S99 WeakPolarHBondContact O-CB 3.49Å; C96-S99 PolarHBondContact O-N 3.39Å; C96-S99 PolarHBondContact O-OG 3.24Å; C96-C266 WeakPolarHBondContact CA-SG 3.49Å; C96-C266 VanDerWaalsContact CB-SG 3.55Å; C96-C266 PolarHBondContact N-SG 2.83Å; C96-F285 HydrophobicContact CB-CD1 4.17Å; C96-F285 HydrophobicContact CB-CE1 3.83Å
97	G	95.7	Very high	91.8	Very high	0 Å²	0	17 Å²	17	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-67.1	-29.3	177.9	0	0	0	0	0	114.3	M72 P73 I93 L94 S99	M72-G97 WeakPolarHBondContact CB-O 3.31Å; P73-G97 WeakPolarHBondContact CD-O 3.38Å; P73-G97 WeakPolarHBondContact CG-O 3.32Å; I93-G97 PolarHBondContact O-N 3.3Å; L94-G97 PolarHBondContact O-N 2.97Å; L94-G97 VanDerWaalsContact O-N 3.16Å; G97-S99 VanDerWaalsContact C-N 3.29Å
98	C	95.1	Very high	92.1	Very high	0 Å²	0	13.8 Å²	13.8	0%	0	8%	0.077	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.4	-2.1	175.1	-64.7	0	0	0	0	113.8	L94 C96 M134 L138	L94-C98 WeakPolarHBondContact O-CB 3.33Å; L94-C98 PolarHBondContact O-N 2.96Å; L94-C98 PolarHBondContact O-SG 2.88Å; C96-C98 VanDerWaalsContact C-N 3.33Å; C96-C98 PolarHBondContact O-N 3.42Å; C98-M134 HydrophobicContact CB-CB 4.49Å; C98-M134 HydrophobicContact CB-CG 3.9Å; C98-L138 HydrophobicContact CB-CG 4.49Å
99	S	94.1	Very high	92.4	Very high	0 Å²	0	11.3 Å²	11.3	0%	0	6%	0.064	C	C	.	.	S	Bend	trans	-70	154.3	176.5	-66.6	0	0	0	0	110.9	Q68 V95 C96 G97 Q261	Q68-S99 PolarHBondContact NE2-O 2.86Å; V95-S99 PolarHBondContact O-N 3.31Å; V95-S99 PolarHBondContact O-OG 3.48Å; C96-S99 VanDerWaalsContact O-CB 3.26Å; C96-S99 WeakPolarHBondContact O-CB 3.49Å; C96-S99 PolarHBondContact O-N 3.39Å; C96-S99 PolarHBondContact O-OG 3.24Å; G97-S99 VanDerWaalsContact C-N 3.29Å; S99-Q261 VanDerWaalsContact C-OE1 3.27Å; S99-Q261 PolarHBondContact O-OE1 3.02Å
100	P	94.3	Very high	92.5	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	9%	0.087	C	C	.	.	P	Polyproline II helix	trans	-71.9	170.6	171.4	31.4	-34.6	0	0	0	111.1	A130 Q261 N262 L265	P100-A130 HydrophobicContact CB-CB 4.27Å; P100-A130 HydrophobicContact CG-CB 4.08Å; P100-Q261 PolarHBondContact O-OE1 2.92Å; P100-N262 HydrophobicContact CG-CB 4.22Å; P100-N262 VanDerWaalsContact O-CB 3.23Å; P100-N262 WeakPolarHBondContact O-CB 3.48Å; P100-N262 PolarHBondContact O-N 2.83Å; P100-L265 HydrophobicContact CG-CD1 3.92Å
101	G	90.2	Very high	92.6	Very high	0 Å²	0	16.5 Å²	16.5	0%	0	9%	0.094	C	C	.	.	B	Isolated β-bridge	trans	-56.5	149.7	175.4	0	0	0	0	0	112.2	T123 S126 C260	G101-T123 WeakPolarHBondContact O-CG2 3.39Å; G101-S126 PolarHBondContact N-OG 3.5Å; G101-C260 WeakPolarHBondContact CA-O 3.33Å
102	G	86.7	Confident	92.7	Very high	3 Å²	3	17.2 Å²	17.2	3%	0.031	10%	0.098	C	C	.	.			trans	-105.4	154.5	-177.9	0	0	0	0	0	113.8	L104 S105 C260	G102-L104 PolarHBondContact O-N 3.08Å; G102-S105 WeakPolarHBondContact O-CB 3.36Å; G102-S105 PolarHBondContact O-N 2.74Å; G102-S105 PolarHBondContact O-OG 3.49Å; G102-C260 PolarHBondContact N-O 2.88Å
103	N	84.3	Confident	92.7	Very high	50 Å²	50	21.7 Å²	21.7	27%	0.267	12%	0.117	S	C	.	.	T	Hydrogen-bonded Turn	trans	-55.8	-22	-178.4	-63.1	-5.5	0	0	0	115.1	L42 S105 N106	L42-N103 WeakPolarHBondContact CD1-OD1 3.39Å; N103-S105 PolarHBondContact O-N 3.16Å; N103-N106 WeakPolarHBondContact O-CB 3.48Å; N103-N106 PolarHBondContact O-N 2.93Å
104	L	89.1	Confident	92.5	Very high	52 Å²	52	22.3 Å²	22.3	27%	0.272	12%	0.124	S	C	.	.	H	α-helix	trans	-64.3	-30	175.6	-71.2	173.8	0	0	0	112.2	G102 N106 V107 F108 Q293	G102-L104 PolarHBondContact O-N 3.08Å; L104-N106 PolarHBondContact O-N 3.43Å; L104-V107 PolarHBondContact O-N 2.95Å; L104-F108 PolarHBondContact O-N 2.75Å; L104-Q293 HydrophobicContact CD1-CG 4.45Å
105	S	91.6	Very high	92.3	Very high	0 Å²	0	24 Å²	24	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-57.8	-38.7	175.6	68.8	0	0	0	0	111.5	G102 N103 V107 F108 S109 T123 E257	G102-S105 WeakPolarHBondContact O-CB 3.36Å; G102-S105 PolarHBondContact O-N 2.74Å; G102-S105 PolarHBondContact O-OG 3.49Å; N103-S105 PolarHBondContact O-N 3.16Å; S105-V107 VanDerWaalsContact C-N 3.34Å; S105-V107 PolarHBondContact O-N 2.79Å; S105-F108 PolarHBondContact O-N 2.82Å; S105-S109 WeakPolarHBondContact O-CB 3.28Å; S105-S109 PolarHBondContact O-N 2.97Å; S105-S109 PolarHBondContact O-OG 3.49Å; S105-T123 PolarHBondContact OG-OG1 2.96Å; S105-E257 WeakPolarHBondContact CB-OE2 3.44Å; S105-E257 PolarHBondContact OG-OE2 2.96Å
106	N	92.1	Very high	92	Very high	18 Å²	18	27.6 Å²	27.6	10%	0.096	15%	0.15	C	C	.	.	H	α-helix	trans	-62.6	-42.5	179.9	-64.8	-35.5	0	0	0	111.6	N103 L104 L110 S119 I120	N103-N106 WeakPolarHBondContact O-CB 3.48Å; N103-N106 PolarHBondContact O-N 2.93Å; L104-N106 PolarHBondContact O-N 3.43Å; N106-L110 PolarHBondContact O-N 3.44Å; N106-L110 VanDerWaalsContact O-N 3.11Å; N106-S119 VanDerWaalsContact OD1-CB 3.26Å; N106-S119 WeakPolarHBondContact OD1-CB 3.48Å; N106-S119 PolarHBondContact OD1-OG 3.23Å; N106-S119 VanDerWaalsContact OD1-OG 3.12Å; N106-I120 PolarHBondContact OD1-N 3.14Å
107	V	92	Very high	91.7	Very high	88 Å²	88	30.3 Å²	30.3	53%	0.533	17%	0.165	S	C	.	.	H	α-helix	trans	-69.2	-44.5	178.9	-179.4	0	0	0	0	110.4	L104 S105 L110 A111	L104-V107 PolarHBondContact O-N 2.95Å; S105-V107 VanDerWaalsContact C-N 3.34Å; S105-V107 PolarHBondContact O-N 2.79Å; V107-L110 PolarHBondContact O-N 3.42Å; V107-A111 WeakPolarHBondContact O-CB 3.3Å; V107-A111 PolarHBondContact O-N 3.44Å
108	F	94.9	Very high	91.3	Very high	7 Å²	7	30.6 Å²	30.6	3%	0.031	17%	0.167	C	C	.	.	H	α-helix	trans	-68.5	-40.5	178.8	-67.8	-16	0	0	0	112.8	L104 S105 L110 A111 M112 M256 C260 Q293 L294 L298 I301	L104-F108 PolarHBondContact O-N 2.75Å; S105-F108 PolarHBondContact O-N 2.82Å; F108-L110 VanDerWaalsContact C-N 3.29Å; F108-L110 PolarHBondContact O-N 3.01Å; F108-A111 PolarHBondContact O-N 2.84Å; F108-A111 VanDerWaalsContact O-N 3.17Å; F108-M112 VanDerWaalsContact O-CB 3.3Å; F108-M112 WeakPolarHBondContact O-CB 3.43Å; F108-M112 VanDerWaalsContact O-CG 3.22Å; F108-M112 WeakPolarHBondContact O-CG 3.28Å; F108-M112 PolarHBondContact O-N 3.27Å; F108-M256 HydrophobicContact CB-CB 4.19Å; F108-M256 HydrophobicContact CB-CG 3.9Å; F108-M256 HydrophobicContact CB-SD 3.69Å; F108-M256 HydrophobicContact CD2-SD 4.25Å; F108-M256 HydrophobicContact CG-SD 4.38Å; F108-C260 VanDerWaalsContact CD2-SG 3.57Å; F108-Q293 WeakPolarHBondContact CE2-O 3.06Å; F108-L294 HydrophobicContact CZ-CD1 4.02Å; F108-L298 HydrophobicContact CE1-CD2 4.42Å; F108-I301 HydrophobicContact CB-CD1 4.4Å; F108-I301 HydrophobicContact CD1-CD1 3.55Å; F108-I301 HydrophobicContact CE1-CD1 4.03Å; F108-I301 HydrophobicContact CG-CD1 4.16Å
109	S	94.1	Very high	91.1	Very high	0 Å²	0	30.6 Å²	30.6	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-54.7	-46.9	171	-73.2	0	0	0	0	110.7	S105 M112 K113 G114 S119	S105-S109 WeakPolarHBondContact O-CB 3.28Å; S105-S109 PolarHBondContact O-N 2.97Å; S105-S109 PolarHBondContact O-OG 3.49Å; S109-M112 PolarHBondContact O-N 3.17Å; S109-K113 PolarHBondContact O-N 3.39Å; S109-G114 WeakPolarHBondContact O-CA 3.31Å; S109-G114 PolarHBondContact O-N 2.9Å; S109-S119 PolarHBondContact OG-OG 3.23Å; S109-S119 VanDerWaalsContact OG-OG 3.08Å
110	L	92.9	Very high	90.9	Very high	102 Å²	102	31.4 Å²	31.4	53%	0.534	17%	0.171	S	C	.	.	H	α-helix	trans	-63.1	-46.3	175.6	-178.4	64.1	0	0	0	112.1	N106 V107 F108 M112 K113 M116	N106-L110 PolarHBondContact O-N 3.44Å; N106-L110 VanDerWaalsContact O-N 3.11Å; V107-L110 PolarHBondContact O-N 3.42Å; F108-L110 VanDerWaalsContact C-N 3.29Å; F108-L110 PolarHBondContact O-N 3.01Å; L110-M112 VanDerWaalsContact C-N 3.26Å; L110-M112 PolarHBondContact O-N 2.9Å; L110-K113 PolarHBondContact O-N 3.31Å; L110-M116 HydrophobicContact CB-SD 4.36Å; L110-M116 HydrophobicContact CD1-SD 4.13Å; L110-M116 HydrophobicContact CD2-SD 4.17Å; L110-M116 HydrophobicContact CG-SD 4.46Å
111	A	93.7	Very high	90.7	Very high	25 Å²	25	31.4 Å²	31.4	21%	0.207	17%	0.171	C	C	.	.	H	α-helix	trans	-63.2	-31.9	-179.3	0	0	0	0	0	113	V107 F108 K113 I301 R305	V107-A111 WeakPolarHBondContact O-CB 3.3Å; V107-A111 PolarHBondContact O-N 3.44Å; F108-A111 PolarHBondContact O-N 2.84Å; F108-A111 VanDerWaalsContact O-N 3.17Å; A111-K113 VanDerWaalsContact C-N 3.26Å; A111-K113 PolarHBondContact O-N 3.11Å; A111-I301 HydrophobicContact CB-CD1 3.57Å; A111-I301 HydrophobicContact CB-CG1 3.93Å; A111-I301 HydrophobicContact CB-CG2 4.2Å; A111-R305 PolarHBondContact O-NE 3.32Å; A111-R305 PolarHBondContact O-NH2 2.77Å
112	M	93.3	Very high	90.7	Very high	15 Å²	15	31.5 Å²	31.5	7%	0.074	17%	0.171	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.4	8.2	174.9	-68.7	-66.9	-78.4	0	0	113.6	F108 S109 L110 G114 R252 M256 I301 F304	F108-M112 VanDerWaalsContact O-CB 3.3Å; F108-M112 WeakPolarHBondContact O-CB 3.43Å; F108-M112 VanDerWaalsContact O-CG 3.22Å; F108-M112 WeakPolarHBondContact O-CG 3.28Å; F108-M112 PolarHBondContact O-N 3.27Å; S109-M112 PolarHBondContact O-N 3.17Å; L110-M112 VanDerWaalsContact C-N 3.26Å; L110-M112 PolarHBondContact O-N 2.9Å; M112-G114 PolarHBondContact O-N 2.69Å; M112-G114 VanDerWaalsContact O-N 3.16Å; M112-R252 HydrophobicContact CB-CB 4.38Å; M112-R252 WeakPolarHBondContact O-CD 3.39Å; M112-R252 PolarHBondContact O-NE 3.24Å; M112-M256 HydrophobicContact CE-CE 3.81Å; M112-M256 HydrophobicContact CG-CE 3.51Å; M112-M256 HydrophobicContact CG-CG 4.32Å; M112-M256 HydrophobicContact CG-SD 4.48Å; M112-M256 HydrophobicContact SD-CE 3.96Å; M112-I301 HydrophobicContact CG-CG1 3.85Å; M112-I301 WeakPolarHBondContact SD-CA 3.34Å; M112-I301 HydrophobicContact SD-CB 4.16Å; M112-I301 HydrophobicContact SD-CG1 3.7Å; M112-F304 HydrophobicContact CE-CB 3.47Å; M112-F304 VanDerWaalsContact CE-CB 3.47Å; M112-F304 HydrophobicContact CE-CD1 4.36Å; M112-F304 HydrophobicContact CE-CD2 4.14Å; M112-F304 HydrophobicContact CE-CG 3.74Å; M112-F304 WeakPolarHBondContact O-CE1 3.29Å; M112-F304 WeakPolarHBondContact O-CZ 3.47Å; M112-F304 HydrophobicContact SD-CB 3.54Å; M112-F304 VanDerWaalsContact SD-CB 3.54Å; M112-F304 HydrophobicContact SD-CD1 3.95Å; M112-F304 HydrophobicContact SD-CG 3.84Å
113	K	93.1	Very high	90.9	Very high	95 Å²	95	31.4 Å²	31.4	41%	0.413	17%	0.17	S	C	.	.	T	Hydrogen-bonded Turn	trans	52.9	33.2	-172.2	-56.2	178.8	178.3	171.6	0	112.5	S109 L110 A111 R252 F304 E308	S109-K113 PolarHBondContact O-N 3.39Å; L110-K113 PolarHBondContact O-N 3.31Å; A111-K113 VanDerWaalsContact C-N 3.26Å; A111-K113 PolarHBondContact O-N 3.11Å; K113-R252 PolarHBondContact O-NH2 2.87Å; K113-F304 HydrophobicContact CB-CE1 4.34Å; K113-F304 HydrophobicContact CB-CZ 4.48Å; K113-F304 HydrophobicContact CD-CE1 4.22Å; K113-F304 HydrophobicContact CD-CZ 4.46Å; K113-F304 HydrophobicContact CG-CE1 4.21Å; K113-E308 WeakPolarHBondContact CE-OE2 3.21Å; K113-E308 IonicContact NZ-OE1 2.78Å; K113-E308 PolarHBondContact NZ-OE1 2.85Å; K113-E308 IonicContact NZ-OE2 3.34Å; K113-E308 PolarHBondContact NZ-OE2 2.9Å
114	G	91.3	Very high	91.1	Very high	14 Å²	14	29.1 Å²	29.1	14%	0.144	16%	0.158	C	C	.	.			trans	-74.4	-175.2	172.7	0	0	0	0	0	111.9	S109 M112 R249	S109-G114 WeakPolarHBondContact O-CA 3.31Å; S109-G114 PolarHBondContact O-N 2.9Å; M112-G114 PolarHBondContact O-N 2.69Å; M112-G114 VanDerWaalsContact O-N 3.16Å; G114-R249 WeakPolarHBondContact CA-O 3.41Å
115	D	90.7	Very high	91.2	Very high	36 Å²	36	27.7 Å²	27.7	19%	0.193	15%	0.152	C	C	.	.			trans	-86.6	106	169.3	-170.1	-30.1	0	0	0	109.9	N117 L118 S119 T253	D115-N117 WeakPolarHBondContact OD1-CB 3.25Å; D115-N117 PolarHBondContact OD1-N 2.94Å; D115-L118 HydrophobicContact CB-CB 3.74Å; D115-L118 HydrophobicContact CB-CD2 4.36Å; D115-L118 PolarHBondContact OD1-N 3.37Å; D115-S119 PolarHBondContact O-N 3.46Å; D115-T253 WeakPolarHBondContact CA-OG1 3.48Å; D115-T253 PolarHBondContact N-OG1 3.47Å; D115-T253 VanDerWaalsContact O-CG2 3.28Å; D115-T253 WeakPolarHBondContact O-CG2 3.15Å; D115-T253 PolarHBondContact O-OG1 3.46Å
116	M	87.8	Confident	91.2	Very high	74 Å²	74	27.8 Å²	27.8	37%	0.365	15%	0.153	S	C	.	.	H	α-helix	trans	-70.8	-33	179.6	-174.6	-179.7	68.4	0	0	112.4	L110 L118 S119 I120	L110-M116 HydrophobicContact CB-SD 4.36Å; L110-M116 HydrophobicContact CD1-SD 4.13Å; L110-M116 HydrophobicContact CD2-SD 4.17Å; L110-M116 HydrophobicContact CG-SD 4.46Å; M116-L118 VanDerWaalsContact C-N 3.29Å; M116-L118 PolarHBondContact O-N 3.43Å; M116-S119 PolarHBondContact O-N 2.9Å; M116-I120 HydrophobicContact CG-CD1 4.1Å; M116-I120 WeakPolarHBondContact O-CG1 3.35Å; M116-I120 PolarHBondContact O-N 2.94Å; M116-I120 VanDerWaalsContact O-N 3.1Å
117	N	88.1	Confident	91.2	Very high	57 Å²	57	27 Å²	27	31%	0.305	15%	0.149	S	C	.	.	H	α-helix	trans	-66.6	-40.1	178.3	-65	-38	0	0	0	110.1	K50 D115 I120 V121	K50-N117 HydrophobicContact CD-CB 4.37Å; K50-N117 WeakPolarHBondContact CD-OD1 3.21Å; K50-N117 VanDerWaalsContact CE-OD1 3.24Å; K50-N117 WeakPolarHBondContact CE-OD1 3.48Å; K50-N117 PolarHBondContact NZ-OD1 3.44Å; D115-N117 WeakPolarHBondContact OD1-CB 3.25Å; D115-N117 PolarHBondContact OD1-N 2.94Å; N117-I120 PolarHBondContact O-N 3.26Å; N117-V121 WeakPolarHBondContact O-CG2 3.23Å; N117-V121 PolarHBondContact O-N 3.33Å; N117-V121 VanDerWaalsContact O-N 3.1Å
118	L	88.3	Confident	91.1	Very high	7 Å²	7	26.8 Å²	26.8	4%	0.037	14%	0.141	C	C	.	.	H	α-helix	trans	-62.6	-43.6	175.1	-173.7	63	0	0	0	111.5	D115 M116 V121 M122 C250 T253	D115-L118 HydrophobicContact CB-CB 3.74Å; D115-L118 HydrophobicContact CB-CD2 4.36Å; D115-L118 PolarHBondContact OD1-N 3.37Å; M116-L118 VanDerWaalsContact C-N 3.29Å; M116-L118 PolarHBondContact O-N 3.43Å; L118-V121 PolarHBondContact O-N 2.93Å; L118-M122 HydrophobicContact CD1-CE 3.48Å; L118-M122 VanDerWaalsContact CD1-CE 3.48Å; L118-M122 HydrophobicContact CD1-CG 4.47Å; L118-M122 HydrophobicContact CD1-SD 4.44Å; L118-M122 HydrophobicContact CD2-CE 3.52Å; L118-M122 HydrophobicContact CG-CE 3.26Å; L118-M122 HydrophobicContact CG-CG 4.45Å; L118-M122 HydrophobicContact CG-SD 3.92Å; L118-M122 WeakPolarHBondContact O-CB 3.44Å; L118-M122 WeakPolarHBondContact O-CG 3.39Å; L118-M122 PolarHBondContact O-N 3.3Å; L118-C250 HydrophobicContact CD2-CB 3.69Å; L118-T253 HydrophobicContact CB-CG2 4.13Å; L118-T253 HydrophobicContact CD2-CG2 4.27Å; L118-T253 HydrophobicContact CG-CG2 4.15Å
119	S	91.3	Very high	91	Very high	0 Å²	0	28.8 Å²	28.8	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-56.8	-52.6	176.7	-151.6	0	0	0	0	110.9	N106 S109 D115 M116 V121 M122 T123 E257	N106-S119 VanDerWaalsContact OD1-CB 3.26Å; N106-S119 WeakPolarHBondContact OD1-CB 3.48Å; N106-S119 PolarHBondContact OD1-OG 3.23Å; N106-S119 VanDerWaalsContact OD1-OG 3.12Å; S109-S119 PolarHBondContact OG-OG 3.23Å; S109-S119 VanDerWaalsContact OG-OG 3.08Å; D115-S119 PolarHBondContact O-N 3.46Å; M116-S119 PolarHBondContact O-N 2.9Å; S119-V121 VanDerWaalsContact C-N 3.31Å; S119-V121 PolarHBondContact O-N 3.29Å; S119-M122 WeakPolarHBondContact O-CB 3.08Å; S119-M122 PolarHBondContact O-N 3.36Å; S119-M122 VanDerWaalsContact O-N 3.08Å; S119-T123 PolarHBondContact O-N 3.35Å; S119-T123 PolarHBondContact O-OG1 3.41Å; S119-E257 PolarHBondContact OG-OE2 3.44Å
120	I	88.8	Confident	90.8	Very high	16 Å²	16	28.8 Å²	28.8	8%	0.082	16%	0.155	C	C	.	.	H	α-helix	trans	-61.1	-40.4	-177.7	-62.8	166.3	0	0	0	111.2	M46 N106 M116 N117 T124	M46-I120 HydrophobicContact CB-CG2 4.18Å; M46-I120 HydrophobicContact CE-CG2 3.87Å; M46-I120 WeakPolarHBondContact CE-O 3.33Å; M46-I120 HydrophobicContact CG-CG2 4.48Å; M46-I120 HydrophobicContact SD-CG2 3.66Å; N106-I120 PolarHBondContact OD1-N 3.14Å; M116-I120 HydrophobicContact CG-CD1 4.1Å; M116-I120 WeakPolarHBondContact O-CG1 3.35Å; M116-I120 PolarHBondContact O-N 2.94Å; M116-I120 VanDerWaalsContact O-N 3.1Å; N117-I120 PolarHBondContact O-N 3.26Å; I120-T124 WeakPolarHBondContact O-CB 3.33Å; I120-T124 PolarHBondContact O-N 3.43Å; I120-T124 PolarHBondContact O-OG1 2.94Å
121	V	89.4	Confident	90.8	Very high	0 Å²	0	26.9 Å²	26.9	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-65	-45.1	174.7	173.2	0	0	0	0	111.5	M46 H54 L61 N117 L118 S119 T124 C125	M46-V121 HydrophobicContact CE-CB 4.27Å; M46-V121 HydrophobicContact CE-CG2 3.79Å; H54-V121 HydrophobicContact CB-CB 4.41Å; H54-V121 HydrophobicContact CB-CG1 3.94Å; H54-V121 HydrophobicContact CB-CG2 4.17Å; L61-V121 HydrophobicContact CD1-CG1 4.14Å; L61-V121 HydrophobicContact CD2-CG1 4.27Å; N117-V121 WeakPolarHBondContact O-CG2 3.23Å; N117-V121 PolarHBondContact O-N 3.33Å; N117-V121 VanDerWaalsContact O-N 3.1Å; L118-V121 PolarHBondContact O-N 2.93Å; S119-V121 VanDerWaalsContact C-N 3.31Å; S119-V121 PolarHBondContact O-N 3.29Å; V121-T124 PolarHBondContact O-N 3.45Å; V121-C125 VanDerWaalsContact O-CB 3.26Å; V121-C125 WeakPolarHBondContact O-CB 3.32Å; V121-C125 PolarHBondContact O-N 3.25Å; V121-C125 PolarHBondContact O-SG 3.19Å; V121-C125 VanDerWaalsContact O-SG 3.33Å
122	M	90.3	Very high	90.6	Very high	3 Å²	3	28 Å²	28	2%	0.015	16%	0.158	C	C	.	.	H	α-helix	trans	-60.7	-46.4	177.1	-68.9	168.9	173.3	0	0	111.9	G60 L61 A64 L118 S119 T124 C125 S126 T253 V254 E257	G60-M122 VanDerWaalsContact O-CE 3.28Å; G60-M122 WeakPolarHBondContact O-CE 3.16Å; L61-M122 HydrophobicContact CD1-CG 4.21Å; A64-M122 HydrophobicContact CB-CB 4.26Å; A64-M122 HydrophobicContact CB-CE 3.36Å; A64-M122 HydrophobicContact CB-CG 3.55Å; A64-M122 HydrophobicContact CB-SD 3.35Å; A64-M122 WeakPolarHBondContact CB-SD 3.32Å; L118-M122 HydrophobicContact CD1-CE 3.48Å; L118-M122 VanDerWaalsContact CD1-CE 3.48Å; L118-M122 HydrophobicContact CD1-CG 4.47Å; L118-M122 HydrophobicContact CD1-SD 4.44Å; L118-M122 HydrophobicContact CD2-CE 3.52Å; L118-M122 HydrophobicContact CG-CE 3.26Å; L118-M122 HydrophobicContact CG-CG 4.45Å; L118-M122 HydrophobicContact CG-SD 3.92Å; L118-M122 WeakPolarHBondContact O-CB 3.44Å; L118-M122 WeakPolarHBondContact O-CG 3.39Å; L118-M122 PolarHBondContact O-N 3.3Å; S119-M122 WeakPolarHBondContact O-CB 3.08Å; S119-M122 PolarHBondContact O-N 3.36Å; S119-M122 VanDerWaalsContact O-N 3.08Å; M122-T124 VanDerWaalsContact C-N 3.35Å; M122-T124 PolarHBondContact O-N 2.93Å; M122-C125 PolarHBondContact O-N 2.78Å; M122-S126 VanDerWaalsContact O-CB 3.24Å; M122-S126 WeakPolarHBondContact O-CB 3.41Å; M122-S126 PolarHBondContact O-N 3.29Å; M122-S126 PolarHBondContact O-OG 3.08Å; M122-T253 HydrophobicContact SD-CG2 4.04Å; M122-V254 HydrophobicContact CE-CG2 3.54Å; M122-V254 HydrophobicContact SD-CG2 4.23Å; M122-E257 HydrophobicContact CB-CG 3.75Å; M122-E257 HydrophobicContact SD-CB 4.31Å; M122-E257 HydrophobicContact SD-CG 4.26Å
123	T	91.2	Very high	90.6	Very high	0 Å²	0	30.2 Å²	30.2	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-62.4	-43.8	178.8	-49.7	0	0	0	0	111.2	L42 G101 S105 S119 S126 T127 E257	L42-T123 HydrophobicContact CD1-CG2 3.93Å; L42-T123 HydrophobicContact CD2-CG2 3.95Å; G101-T123 WeakPolarHBondContact O-CG2 3.39Å; S105-T123 PolarHBondContact OG-OG1 2.96Å; S119-T123 PolarHBondContact O-N 3.35Å; S119-T123 PolarHBondContact O-OG1 3.41Å; T123-S126 WeakPolarHBondContact CA-OG 3.24Å; T123-S126 PolarHBondContact O-OG 3.01Å; T123-T127 VanDerWaalsContact O-CB 3.29Å; T123-T127 WeakPolarHBondContact O-CB 3.32Å; T123-T127 PolarHBondContact O-N 3.05Å; T123-T127 PolarHBondContact O-OG1 3.3Å; T123-E257 WeakPolarHBondContact CA-OE1 3.25Å; T123-E257 WeakPolarHBondContact CB-OE1 3.47Å; T123-E257 PolarHBondContact N-OE1 3.43Å; T123-E257 VanDerWaalsContact OG1-CD 3.25Å; T123-E257 PolarHBondContact OG1-OE1 3.27Å; T123-E257 PolarHBondContact OG1-OE2 3.24Å; T123-E257 VanDerWaalsContact OG1-OE2 3.05Å
124	T	89.3	Confident	90.6	Very high	3 Å²	3	25.7 Å²	25.7	2%	0.018	15%	0.15	C	C	.	.	H	α-helix	trans	-67.6	-51.2	-179.6	-58.6	0	0	0	0	110.6	M46 I120 V121 M122 S126 T127 F128 I174	M46-T124 HydrophobicContact CE-CG2 3.91Å; M46-T124 VanDerWaalsContact CE-OG1 3.26Å; M46-T124 WeakPolarHBondContact CE-OG1 3.22Å; I120-T124 WeakPolarHBondContact O-CB 3.33Å; I120-T124 PolarHBondContact O-N 3.43Å; I120-T124 PolarHBondContact O-OG1 2.94Å; V121-T124 PolarHBondContact O-N 3.45Å; M122-T124 VanDerWaalsContact C-N 3.35Å; M122-T124 PolarHBondContact O-N 2.93Å; T124-S126 VanDerWaalsContact C-N 3.34Å; T124-S126 PolarHBondContact O-N 3.4Å; T124-T127 WeakPolarHBondContact O-CB 3.45Å; T124-T127 PolarHBondContact O-N 2.7Å; T124-T127 VanDerWaalsContact O-N 3.16Å; T124-F128 HydrophobicContact CG2-CD2 3.84Å; T124-F128 HydrophobicContact CG2-CE2 3.66Å; T124-F128 VanDerWaalsContact O-CD2 3.23Å; T124-F128 WeakPolarHBondContact O-CD2 3.22Å; T124-F128 PolarHBondContact O-N 2.69Å; T124-I174 HydrophobicContact CG2-CD1 4.15Å
125	C	90.1	Very high	90.6	Very high	22 Å²	22	25.7 Å²	25.7	15%	0.149	15%	0.147	C	C	.	.	H	α-helix	trans	-60.6	-42.5	178.7	-72.3	0	0	0	0	111.9	L61 V121 M122 T127 F128 C129	L61-C125 HydrophobicContact CD1-CB 3.81Å; V121-C125 VanDerWaalsContact O-CB 3.26Å; V121-C125 WeakPolarHBondContact O-CB 3.32Å; V121-C125 PolarHBondContact O-N 3.25Å; V121-C125 PolarHBondContact O-SG 3.19Å; V121-C125 VanDerWaalsContact O-SG 3.33Å; M122-C125 PolarHBondContact O-N 2.78Å; C125-T127 VanDerWaalsContact C-N 3.34Å; C125-T127 PolarHBondContact O-N 3.08Å; C125-F128 PolarHBondContact O-N 2.88Å; C125-C129 WeakPolarHBondContact O-CB 3.3Å; C125-C129 PolarHBondContact O-N 3.08Å; C125-C129 PolarHBondContact O-SG 3.01Å
126	S	92.3	Very high	90.7	Very high	2 Å²	2	28.9 Å²	28.9	1%	0.014	16%	0.164	C	C	.	.	H	α-helix	trans	-63.3	-41.3	175.7	64.3	0	0	0	0	111.1	Y69 G101 M122 T123 T124 F128 C129 A130	Y69-S126 PolarHBondContact OH-O 3.41Å; G101-S126 PolarHBondContact N-OG 3.5Å; M122-S126 VanDerWaalsContact O-CB 3.24Å; M122-S126 WeakPolarHBondContact O-CB 3.41Å; M122-S126 PolarHBondContact O-N 3.29Å; M122-S126 PolarHBondContact O-OG 3.08Å; T123-S126 WeakPolarHBondContact CA-OG 3.24Å; T123-S126 PolarHBondContact O-OG 3.01Å; T124-S126 VanDerWaalsContact C-N 3.34Å; T124-S126 PolarHBondContact O-N 3.4Å; S126-F128 PolarHBondContact O-N 3Å; S126-C129 CarbonylContact O-C 3.43Å; S126-C129 PolarHBondContact O-N 2.7Å; S126-A130 PolarHBondContact O-N 3.23Å
127	T	91.6	Very high	91	Very high	2 Å²	2	26 Å²	26	1%	0.012	15%	0.15	C	C	.	.	H	α-helix	trans	-59	-44.3	175.4	-60.1	0	0	0	0	112.2	T123 T124 C125 A130 V166 L167	T123-T127 VanDerWaalsContact O-CB 3.29Å; T123-T127 WeakPolarHBondContact O-CB 3.32Å; T123-T127 PolarHBondContact O-N 3.05Å; T123-T127 PolarHBondContact O-OG1 3.3Å; T124-T127 WeakPolarHBondContact O-CB 3.45Å; T124-T127 PolarHBondContact O-N 2.7Å; T124-T127 VanDerWaalsContact O-N 3.16Å; C125-T127 VanDerWaalsContact C-N 3.34Å; C125-T127 PolarHBondContact O-N 3.08Å; T127-A130 VanDerWaalsContact O-CB 3.26Å; T127-A130 WeakPolarHBondContact O-CB 3.45Å; T127-A130 PolarHBondContact O-N 2.59Å; T127-V166 HydrophobicContact CG2-CG1 3.91Å; T127-L167 HydrophobicContact CG2-CD2 4.21Å
128	F	90.4	Very high	91.2	Very high	82 Å²	82	23.3 Å²	23.3	36%	0.36	14%	0.136	S	C	.	.	H	α-helix	trans	-67	-41.2	174.3	-79.6	-79.3	0	0	0	112.4	T124 C125 S126 A130 L131 L167 I174	T124-F128 HydrophobicContact CG2-CD2 3.84Å; T124-F128 HydrophobicContact CG2-CE2 3.66Å; T124-F128 VanDerWaalsContact O-CD2 3.23Å; T124-F128 WeakPolarHBondContact O-CD2 3.22Å; T124-F128 PolarHBondContact O-N 2.69Å; C125-F128 PolarHBondContact O-N 2.88Å; S126-F128 PolarHBondContact O-N 3Å; F128-A130 PolarHBondContact O-N 2.98Å; F128-L131 PolarHBondContact O-N 2.87Å; F128-L167 HydrophobicContact CD1-CD2 3.81Å; F128-L167 HydrophobicContact CE1-CD2 4.14Å; F128-L167 HydrophobicContact CG-CD2 4.24Å; F128-I174 HydrophobicContact CE2-CD1 4.03Å; F128-I174 HydrophobicContact CZ-CD1 4.25Å
129	C	91.9	Very high	91.2	Very high	49 Å²	49	27.9 Å²	27.9	33%	0.331	15%	0.153	S	C	.	.	H	α-helix	trans	-65.6	-24.1	176.7	-66.6	0	0	0	0	112.5	Y69 C125 S126 L131 G132 M133	Y69-C129 HydrophobicContact CE2-CB 3.83Å; C125-C129 WeakPolarHBondContact O-CB 3.3Å; C125-C129 PolarHBondContact O-N 3.08Å; C125-C129 PolarHBondContact O-SG 3.01Å; S126-C129 CarbonylContact O-C 3.43Å; S126-C129 PolarHBondContact O-N 2.7Å; C129-L131 PolarHBondContact O-N 3.29Å; C129-L131 VanDerWaalsContact O-N 3.17Å; C129-G132 PolarHBondContact O-N 3.49Å; C129-G132 VanDerWaalsContact O-N 3.12Å; C129-M133 HydrophobicContact CB-CG 4.14Å; C129-M133 WeakPolarHBondContact O-CB 3.49Å; C129-M133 WeakPolarHBondContact O-CG 3.39Å; C129-M133 PolarHBondContact O-N 3.27Å
130	A	91.9	Very high	91.2	Very high	1 Å²	1	33.1 Å²	33.1	1%	0.008	18%	0.18	C	C	.	.	H	α-helix	trans	-57.1	-33.2	-178.4	0	0	0	0	0	112.2	Y69 P100 S126 T127 F128 G132 M134 P135 L163	Y69-A130 WeakPolarHBondContact OH-CA 3.43Å; Y69-A130 VanDerWaalsContact OH-CB 3.24Å; Y69-A130 WeakPolarHBondContact OH-CB 3.42Å; Y69-A130 PolarHBondContact OH-N 3.05Å; Y69-A130 VanDerWaalsContact OH-N 3.15Å; P100-A130 HydrophobicContact CB-CB 4.27Å; P100-A130 HydrophobicContact CG-CB 4.08Å; S126-A130 PolarHBondContact O-N 3.23Å; T127-A130 VanDerWaalsContact O-CB 3.26Å; T127-A130 WeakPolarHBondContact O-CB 3.45Å; T127-A130 PolarHBondContact O-N 2.59Å; F128-A130 PolarHBondContact O-N 2.98Å; A130-G132 PolarHBondContact O-N 3.1Å; A130-M134 WeakPolarHBondContact O-CB 3.47Å; A130-M134 PolarHBondContact O-N 3.31Å; A130-P135 WeakPolarHBondContact O-CD 3.17Å; A130-L163 HydrophobicContact CB-CD2 4.3Å
131	L	91	Very high	91.4	Very high	62 Å²	62	34.1 Å²	34.1	33%	0.325	18%	0.184	S	C	.	.	H	α-helix	trans	-54.8	-37.1	179.2	-170.3	68.3	0	0	0	112.9	F128 C129 P135 I160 L163 V164 L167	F128-L131 PolarHBondContact O-N 2.87Å; C129-L131 PolarHBondContact O-N 3.29Å; C129-L131 VanDerWaalsContact O-N 3.17Å; L131-P135 WeakPolarHBondContact O-CD 2.98Å; L131-P135 WeakPolarHBondContact O-CG 3.37Å; L131-I160 HydrophobicContact CD1-CG2 4.28Å; L131-L163 HydrophobicContact CD1-CB 3.87Å; L131-V164 HydrophobicContact CD1-CG2 4.2Å; L131-L167 HydrophobicContact CB-CD1 4.17Å; L131-L167 HydrophobicContact CD1-CD1 4.29Å; L131-L167 HydrophobicContact CD2-CD1 3.89Å; L131-L167 HydrophobicContact CG-CD1 4.35Å
132	G	90.6	Very high	91.4	Very high	47 Å²	47	34.1 Å²	34.1	49%	0.485	18%	0.184	S	C	.	.	H	α-helix	trans	-100.2	-43.3	177.2	0	0	0	0	0	113.1	C129 A130 P135 L136	C129-G132 PolarHBondContact O-N 3.49Å; C129-G132 VanDerWaalsContact O-N 3.12Å; A130-G132 PolarHBondContact O-N 3.1Å; G132-P135 WeakPolarHBondContact O-CD 3.43Å; G132-L136 WeakPolarHBondContact O-CB 3.36Å; G132-L136 PolarHBondContact O-N 3.18Å
133	M	93.1	Very high	91.2	Very high	62 Å²	62	41 Å²	41	31%	0.305	21%	0.209	S	C	.	.	H	α-helix	trans	-69.3	-40.9	-173.3	-66.9	-58.5	-67.1	0	0	112.4	Y69 C129 L136 L137	Y69-M133 HydrophobicContact CD1-CB 3.69Å; Y69-M133 HydrophobicContact CD1-CG 4.42Å; Y69-M133 HydrophobicContact CD2-CB 4.13Å; Y69-M133 HydrophobicContact CD2-CE 4.48Å; Y69-M133 HydrophobicContact CD2-CG 4Å; Y69-M133 HydrophobicContact CE1-CB 3.67Å; Y69-M133 HydrophobicContact CE2-CB 4.11Å; Y69-M133 HydrophobicContact CE2-CG 4.12Å; Y69-M133 HydrophobicContact CG-CB 3.93Å; Y69-M133 HydrophobicContact CG-CE 4.06Å; Y69-M133 HydrophobicContact CG-CG 4.15Å; C129-M133 HydrophobicContact CB-CG 4.14Å; C129-M133 WeakPolarHBondContact O-CB 3.49Å; C129-M133 WeakPolarHBondContact O-CG 3.39Å; C129-M133 PolarHBondContact O-N 3.27Å; M133-L136 PolarHBondContact O-N 3.34Å; M133-L136 HydrophobicContact SD-CD2 4.42Å; M133-L137 HydrophobicContact CB-CD1 4.27Å; M133-L137 HydrophobicContact CE-CD1 4.28Å; M133-L137 VanDerWaalsContact O-CB 3.3Å; M133-L137 WeakPolarHBondContact O-CB 3.28Å; M133-L137 WeakPolarHBondContact O-CD1 3.32Å; M133-L137 WeakPolarHBondContact O-CG 3.33Å; M133-L137 PolarHBondContact O-N 3.04Å
134	M	93.1	Very high	90.9	Very high	0 Å²	0	42.4 Å²	42.4	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-65.5	-49.5	-176.3	-177.2	176.5	-168.9	0	0	112.2	V95 C98 A130 L136 L138 L163 L265 I269	V95-M134 HydrophobicContact CB-CE 4.37Å; V95-M134 HydrophobicContact CG1-CE 3.59Å; V95-M134 WeakPolarHBondContact O-CE 3.43Å; C98-M134 HydrophobicContact CB-CB 4.49Å; C98-M134 HydrophobicContact CB-CG 3.9Å; A130-M134 WeakPolarHBondContact O-CB 3.47Å; A130-M134 PolarHBondContact O-N 3.31Å; M134-L136 VanDerWaalsContact C-N 3.34Å; M134-L136 PolarHBondContact O-N 3.49Å; M134-L138 HydrophobicContact CE-CD1 4.42Å; M134-L138 HydrophobicContact CG-CD1 4.04Å; M134-L138 WeakPolarHBondContact O-CB 3.32Å; M134-L138 VanDerWaalsContact O-CG 3.24Å; M134-L138 WeakPolarHBondContact O-CG 3.44Å; M134-L138 PolarHBondContact O-N 3.4Å; M134-L163 HydrophobicContact CB-CD1 4.25Å; M134-L163 HydrophobicContact SD-CD1 4.15Å; M134-L163 HydrophobicContact SD-CD2 4.12Å; M134-L265 HydrophobicContact SD-CD2 4.32Å; M134-I269 HydrophobicContact CE-CD1 3.51Å; M134-I269 HydrophobicContact CE-CG2 4.2Å; M134-I269 HydrophobicContact SD-CD1 3.53Å; M134-I269 VanDerWaalsContact SD-CD1 3.53Å
135	P	91.3	Very high	90.7	Very high	14 Å²	14	43 Å²	43	9%	0.091	23%	0.227	C	C	.	.	H	α-helix	trans	-60.8	-40.8	173	-21.5	31.7	0	0	0	113.1	A130 L131 G132 Y139 I160 L163	A130-P135 WeakPolarHBondContact O-CD 3.17Å; L131-P135 WeakPolarHBondContact O-CD 2.98Å; L131-P135 WeakPolarHBondContact O-CG 3.37Å; G132-P135 WeakPolarHBondContact O-CD 3.43Å; P135-Y139 VanDerWaalsContact O-CB 3.32Å; P135-Y139 WeakPolarHBondContact O-CB 3.27Å; P135-Y139 PolarHBondContact O-N 3.41Å; P135-I160 HydrophobicContact CB-CD1 4.32Å; P135-I160 HydrophobicContact CB-CG1 4.11Å; P135-I160 HydrophobicContact CG-CD1 4.17Å; P135-I160 HydrophobicContact CG-CG1 3.48Å; P135-I160 VanDerWaalsContact CG-CG1 3.48Å; P135-L163 HydrophobicContact CG-CD1 4.46Å
136	L	92.4	Very high	90.3	Very high	104 Å²	104	42.8 Å²	42.8	55%	0.545	22%	0.223	S	C	.	.	H	α-helix	trans	-62.7	-47.4	-179.6	179.5	69.9	0	0	0	112	G132 M133 M134 Y139 L140	G132-L136 WeakPolarHBondContact O-CB 3.36Å; G132-L136 PolarHBondContact O-N 3.18Å; M133-L136 PolarHBondContact O-N 3.34Å; M133-L136 HydrophobicContact SD-CD2 4.42Å; M134-L136 VanDerWaalsContact C-N 3.34Å; M134-L136 PolarHBondContact O-N 3.49Å; L136-Y139 WeakPolarHBondContact O-CB 3.48Å; L136-Y139 PolarHBondContact O-N 3.1Å; L136-L140 PolarHBondContact O-N 3.48Å
137	L	93.9	Very high	89.4	Confident	14 Å²	14	49.9 Å²	49.9	7%	0.073	26%	0.261	C	S	.	.	H	α-helix	trans	-69.7	-41.5	-179.5	-69.3	163.5	0	0	0	111.2	Y69 P73 M133 Y139 L140 Y141	Y69-L137 HydrophobicContact CD1-CD1 3.49Å; Y69-L137 VanDerWaalsContact CD1-CD1 3.49Å; Y69-L137 HydrophobicContact CE1-CD1 4.43Å; Y69-L137 HydrophobicContact CG-CD1 4.11Å; P73-L137 HydrophobicContact CB-CD1 4.46Å; P73-L137 HydrophobicContact CG-CD1 3.79Å; M133-L137 HydrophobicContact CB-CD1 4.27Å; M133-L137 HydrophobicContact CE-CD1 4.28Å; M133-L137 VanDerWaalsContact O-CB 3.3Å; M133-L137 WeakPolarHBondContact O-CB 3.28Å; M133-L137 WeakPolarHBondContact O-CD1 3.32Å; M133-L137 WeakPolarHBondContact O-CG 3.33Å; M133-L137 PolarHBondContact O-N 3.04Å; L137-Y139 VanDerWaalsContact C-N 3.26Å; L137-Y139 PolarHBondContact O-N 2.88Å; L137-L140 PolarHBondContact O-N 3.06Å; L137-Y141 HydrophobicContact CB-CD2 4.4Å; L137-Y141 HydrophobicContact CD2-CE2 4.01Å; L137-Y141 VanDerWaalsContact O-CD2 3.27Å; L137-Y141 WeakPolarHBondContact O-CD2 3.37Å; L137-Y141 PolarHBondContact O-N 3.34Å
138	L	92	Very high	88.4	Confident	0 Å²	0	52.9 Å²	52.9	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-57.9	-43.7	172.4	-74.4	171.2	0	0	0	110.7	L91 L94 V95 C98 M134 L140 T142 Y156 I159	L91-L138 HydrophobicContact CD1-CD2 4.34Å; L94-L138 HydrophobicContact CB-CD2 4.43Å; L94-L138 HydrophobicContact CD2-CD2 3.82Å; L94-L138 HydrophobicContact CG-CD2 3.81Å; V95-L138 HydrophobicContact CG2-CD1 4.24Å; V95-L138 HydrophobicContact CG2-CD2 3.85Å; C98-L138 HydrophobicContact CB-CG 4.49Å; M134-L138 HydrophobicContact CE-CD1 4.42Å; M134-L138 HydrophobicContact CG-CD1 4.04Å; M134-L138 WeakPolarHBondContact O-CB 3.32Å; M134-L138 VanDerWaalsContact O-CG 3.24Å; M134-L138 WeakPolarHBondContact O-CG 3.44Å; M134-L138 PolarHBondContact O-N 3.4Å; L138-L140 VanDerWaalsContact C-N 3.34Å; L138-L140 PolarHBondContact O-N 2.95Å; L138-T142 WeakPolarHBondContact O-CB 3.19Å; L138-T142 WeakPolarHBondContact O-CG2 3.46Å; L138-T142 PolarHBondContact O-N 3Å; L138-T142 PolarHBondContact O-OG1 2.84Å; L138-Y156 HydrophobicContact CB-CE1 4.25Å; L138-I159 HydrophobicContact CD1-CD1 3.62Å; L138-I159 HydrophobicContact CD1-CG2 4.39Å
139	Y	89.8	Confident	87.3	Confident	103 Å²	103	54.4 Å²	54.4	40%	0.404	30%	0.304	S	S	.	.	H	α-helix	trans	-61.1	-42.8	176.6	-179.8	-102.3	0	0	0	112.7	P135 L136 L137 T142 R143 Y156	P135-Y139 VanDerWaalsContact O-CB 3.32Å; P135-Y139 WeakPolarHBondContact O-CB 3.27Å; P135-Y139 PolarHBondContact O-N 3.41Å; L136-Y139 WeakPolarHBondContact O-CB 3.48Å; L136-Y139 PolarHBondContact O-N 3.1Å; L137-Y139 VanDerWaalsContact C-N 3.26Å; L137-Y139 PolarHBondContact O-N 2.88Å; Y139-T142 PolarHBondContact O-OG1 2.88Å; Y139-R143 PolarHBondContact OH-NH2 2.94Å; Y139-Y156 WeakPolarHBondContact CA-OH 3.33Å; Y139-Y156 HydrophobicContact CD2-CE1 4.26Å; Y139-Y156 HydrophobicContact CD2-CE2 4.25Å; Y139-Y156 AromaticContact CD2-CZ 3.83Å
140	L	91.7	Very high	86.2	Confident	109 Å²	109	52.8 Å²	52.8	57%	0.571	29%	0.292	S	S	*	.	H	α-helix	trans	-66.9	-49.9	-179.1	-172	68.6	0	0	0	112.1	L136 L137 L138	L136-L140 PolarHBondContact O-N 3.48Å; L137-L140 PolarHBondContact O-N 3.06Å; L138-L140 VanDerWaalsContact C-N 3.34Å; L138-L140 PolarHBondContact O-N 2.95Å
141	Y	91.7	Very high	84.7	Confident	38 Å²	38	60.8 Å²	60.8	15%	0.149	33%	0.326	C	S	.	.	H	α-helix	trans	-79.8	-28.9	-173.5	-76.5	-72.5	0	0	0	113.4	P73 L74 F77 L94 L137 R143 G144 I145	P73-Y141 HydrophobicContact CB-CD2 4.12Å; P73-Y141 HydrophobicContact CB-CE2 3.61Å; L74-Y141 HydrophobicContact CD1-CE1 4.17Å; F77-Y141 HydrophobicContact CB-CD1 3.5Å; F77-Y141 VanDerWaalsContact CB-CD1 3.5Å; F77-Y141 HydrophobicContact CB-CE1 3.81Å; F77-Y141 HydrophobicContact CB-CG 4.23Å; F77-Y141 AromaticContact CD1-CD1 3.84Å; F77-Y141 HydrophobicContact CD1-CD1 3.84Å; F77-Y141 HydrophobicContact CD1-CE1 4.03Å; F77-Y141 AromaticContact CD2-CD1 3.63Å; F77-Y141 HydrophobicContact CD2-CD1 3.63Å; F77-Y141 HydrophobicContact CD2-CG 4.28Å; F77-Y141 HydrophobicContact CE1-CD1 4.47Å; F77-Y141 HydrophobicContact CE2-CD1 4.28Å; F77-Y141 WeakPolarHBondContact CE2-O 3.35Å; F77-Y141 AromaticContact CG-CD1 3.36Å; F77-Y141 HydrophobicContact CG-CD1 3.36Å; F77-Y141 AromaticContact CG-CE1 3.89Å; F77-Y141 HydrophobicContact CG-CE1 3.89Å; F77-Y141 HydrophobicContact CG-CG 4.31Å; L94-Y141 HydrophobicContact CD1-CD2 4.17Å; L94-Y141 HydrophobicContact CD1-CG 4.08Å; L137-Y141 HydrophobicContact CB-CD2 4.4Å; L137-Y141 HydrophobicContact CD2-CE2 4.01Å; L137-Y141 VanDerWaalsContact O-CD2 3.27Å; L137-Y141 WeakPolarHBondContact O-CD2 3.37Å; L137-Y141 PolarHBondContact O-N 3.34Å; Y141-R143 VanDerWaalsContact C-N 3.25Å; Y141-R143 PolarHBondContact O-N 2.83Å; Y141-G144 WeakPolarHBondContact O-CA 3.49Å; Y141-G144 PolarHBondContact O-N 3.37Å; Y141-I145 PolarHBondContact O-N 2.86Å
142	T	89.3	Confident	83.4	Confident	0 Å²	0	65.1 Å²	65.1	0%	0	35%	0.35	C	S	.	.	H	α-helix	trans	-69	-23.9	179.3	56.3	0	0	0	0	113	L91 L94 L138 Y139 G144 I145 Y146 V154 Y156	L91-T142 HydrophobicContact CD1-CG2 3.89Å; L94-T142 HydrophobicContact CD2-CG2 4.01Å; L138-T142 WeakPolarHBondContact O-CB 3.19Å; L138-T142 WeakPolarHBondContact O-CG2 3.46Å; L138-T142 PolarHBondContact O-N 3Å; L138-T142 PolarHBondContact O-OG1 2.84Å; Y139-T142 PolarHBondContact O-OG1 2.88Å; T142-G144 PolarHBondContact O-N 3.41Å; T142-I145 PolarHBondContact O-N 2.92Å; T142-Y146 PolarHBondContact O-N 3.12Å; T142-V154 HydrophobicContact CG2-CG2 3.88Å; T142-Y156 PolarHBondContact OG1-OH 3.18Å; T142-Y156 VanDerWaalsContact OG1-OH 3.05Å
143	R	86.8	Confident	82.4	Confident	146 Å²	146	66.4 Å²	66.4	55%	0.551	34%	0.342	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.3	-30.4	166.7	-72.1	178	172.9	-153.6	-1.8	113	Y139 Y141 L150	Y139-R143 PolarHBondContact OH-NH2 2.94Å; Y141-R143 VanDerWaalsContact C-N 3.25Å; Y141-R143 PolarHBondContact O-N 2.83Å; R143-L150 HydrophobicContact CB-CD1 4.29Å; R143-L150 HydrophobicContact CG-CD1 3.38Å
144	G	84.4	Confident	81.6	Confident	30 Å²	30	63.5 Å²	63.5	31%	0.309	33%	0.328	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85	-13.2	175.1	0	0	0	0	0	113.5	K81 Y141 T142	K81-G144 WeakPolarHBondContact CE-O 3.48Å; K81-G144 PolarHBondContact NZ-O 3.13Å; Y141-G144 WeakPolarHBondContact O-CA 3.49Å; Y141-G144 PolarHBondContact O-N 3.37Å; T142-G144 PolarHBondContact O-N 3.41Å
145	I	84.6	Confident	81.1	Confident	15 Å²	15	65 Å²	65	8%	0.077	34%	0.338	C	S	.	.	T	Hydrogen-bonded Turn	trans	-96.8	-42.2	-179.4	-63.8	171.5	0	0	0	110.8	F77 N87 A90 L94 Y141 T142	F77-I145 HydrophobicContact CD2-CD1 4.35Å; F77-I145 HydrophobicContact CD2-CG1 4.1Å; F77-I145 HydrophobicContact CE2-CG1 3.98Å; N87-I145 HydrophobicContact CB-CG2 3.96Å; N87-I145 PolarHBondContact OD1-O 3.44Å; A90-I145 HydrophobicContact CB-CD1 3.96Å; A90-I145 HydrophobicContact CB-CG1 4.33Å; A90-I145 HydrophobicContact CB-CG2 4.02Å; L94-I145 HydrophobicContact CD2-CD1 3.83Å; Y141-I145 PolarHBondContact O-N 2.86Å; T142-I145 PolarHBondContact O-N 2.92Å
146	Y	82.1	Confident	80.6	Confident	19 Å²	19	66.5 Å²	66.5	8%	0.075	34%	0.342	C	S	.	.	S	Bend	trans	-112.8	132.8	-175.7	-68.1	-82.8	0	0	0	111.9	N87 I88 T142 L150 K153	N87-Y146 HydrophobicContact CB-CD1 3.84Å; N87-Y146 HydrophobicContact CB-CE1 3.3Å; N87-Y146 HydrophobicContact CB-CE2 4.32Å; N87-Y146 PolarHBondContact O-OH 3.31Å; I88-Y146 WeakPolarHBondContact CD1-OH 3.48Å; T142-Y146 PolarHBondContact O-N 3.12Å; Y146-L150 HydrophobicContact CD2-CD2 4.24Å; Y146-L150 HydrophobicContact CG-CD2 4.44Å; Y146-K153 HydrophobicContact CD1-CD 3.45Å; Y146-K153 VanDerWaalsContact CD1-CD 3.45Å; Y146-K153 HydrophobicContact CD2-CD 4.39Å; Y146-K153 HydrophobicContact CE1-CD 3.99Å; Y146-K153 HydrophobicContact CG-CD 3.64Å
147	D	74.7	Confident	80.1	Confident	150 Å²	150	64.2 Å²	64.2	80%	0.802	34%	0.343	S	S	*	.	S	Bend	trans	-81.6	133	167.7	-58.7	-46.7	0	0	0	110.3	K153	D147-K153 PolarHBondContact O-NZ 2.96Å
148	G	69.8	Low	79.6	Confident	65 Å²	65	70.2 Å²	70.2	67%	0.67	37%	0.365	S	S	*	.	S	Bend	trans	97.3	-162.5	176.1	0	0	0	0	0	116	L150	G148-L150 PolarHBondContact O-N 3.29Å
149	D	67.1	Low	79.2	Confident	115 Å²	115	70.2 Å²	70.2	62%	0.615	37%	0.365	S	S	*	.			trans	-66.1	132.4	-177.9	-164.2	0.1	0	0	0	111.4	K151	D149-K151 PolarHBondContact OD1-N 3.35Å
150	L	68.1	Low	79.1	Confident	15 Å²	15	68.8 Å²	68.8	8%	0.079	36%	0.364	C	S	.	.			trans	-92.8	-11.4	-176	-71.5	167.6	0	0	0	112.6	R143 Y146 G148 D152 K153 V154	R143-L150 HydrophobicContact CB-CD1 4.29Å; R143-L150 HydrophobicContact CG-CD1 3.38Å; Y146-L150 HydrophobicContact CD2-CD2 4.24Å; Y146-L150 HydrophobicContact CG-CD2 4.44Å; G148-L150 PolarHBondContact O-N 3.29Å; L150-D152 PolarHBondContact O-N 2.86Å; L150-K153 PolarHBondContact O-N 3.18Å; L150-V154 PolarHBondContact O-N 3.42Å
151	K	60.6	Low	78.7	Confident	168 Å²	168	69.5 Å²	69.5	73%	0.73	37%	0.367	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.6	-33.3	-169.8	-145.8	176.5	-175.4	-176.3	0	113.4	D149	D149-K151 PolarHBondContact OD1-N 3.35Å
152	D	64.8	Low	78.3	Confident	154 Å²	154	68.5 Å²	68.5	82%	0.824	37%	0.366	S	S	*	.	T	Hydrogen-bonded Turn	trans	-98.8	-7	-179.6	-58.3	-40.7	0	0	0	113.6	L150	L150-D152 PolarHBondContact O-N 2.86Å
153	K	69.6	Low	78.1	Confident	74 Å²	74	68.7 Å²	68.7	32%	0.322	37%	0.367	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.4	-31.6	-172.8	-60.6	-174.3	179.9	177.5	0	113.1	Y146 D147 L150	Y146-K153 HydrophobicContact CD1-CD 3.45Å; Y146-K153 VanDerWaalsContact CD1-CD 3.45Å; Y146-K153 HydrophobicContact CD2-CD 4.39Å; Y146-K153 HydrophobicContact CE1-CD 3.99Å; Y146-K153 HydrophobicContact CG-CD 3.64Å; D147-K153 PolarHBondContact O-NZ 2.96Å; L150-K153 PolarHBondContact O-N 3.18Å
154	V	76.8	Confident	77.9	Confident	1 Å²	1	64.6 Å²	64.6	1%	0.006	36%	0.358	C	S	.	.	S	Bend	trans	-129.3	117.8	-179.6	-177.7	0	0	0	0	109.5	L91 T142 L150 Y156 I159 F274	L91-V154 HydrophobicContact CD1-CG2 4.08Å; L91-V154 HydrophobicContact CD2-CG2 4.49Å; T142-V154 HydrophobicContact CG2-CG2 3.88Å; L150-V154 PolarHBondContact O-N 3.42Å; V154-Y156 VanDerWaalsContact C-N 3.26Å; V154-Y156 HydrophobicContact CB-CD2 4.31Å; V154-Y156 HydrophobicContact CB-CE1 4.1Å; V154-Y156 HydrophobicContact CB-CE2 3.72Å; V154-Y156 HydrophobicContact CG1-CD1 3.94Å; V154-Y156 HydrophobicContact CG1-CD2 4.37Å; V154-Y156 HydrophobicContact CG1-CE1 3.61Å; V154-Y156 HydrophobicContact CG1-CE2 4.07Å; V154-Y156 HydrophobicContact CG1-CG 4.3Å; V154-Y156 WeakPolarHBondContact O-CD2 3.39Å; V154-Y156 WeakPolarHBondContact O-CE2 3.44Å; V154-Y156 PolarHBondContact O-N 3.41Å; V154-I159 HydrophobicContact CG1-CD1 3.87Å; V154-F274 HydrophobicContact CG1-CE1 4.48Å
155	P	81.4	Confident	77.8	Confident	32 Å²	32	66.1 Å²	66.1	21%	0.208	36%	0.362	C	S	.	.			trans	-82.3	68.4	-175.7	34	-33.4	0	0	0	111	G157 R158 I159 A273 F274	P155-G157 VanDerWaalsContact C-N 3.26Å; P155-G157 PolarHBondContact O-N 2.88Å; P155-G157 VanDerWaalsContact O-N 3.16Å; P155-R158 HydrophobicContact CB-CB 4.04Å; P155-R158 HydrophobicContact CB-CG 4.12Å; P155-R158 WeakPolarHBondContact O-CA 3.37Å; P155-R158 WeakPolarHBondContact O-CB 3.32Å; P155-R158 PolarHBondContact O-N 3.22Å; P155-I159 WeakPolarHBondContact O-CG1 3.26Å; P155-I159 PolarHBondContact O-N 3.15Å; P155-A273 WeakPolarHBondContact CG-O 3.48Å; P155-F274 HydrophobicContact CG-CD1 3.84Å; P155-F274 HydrophobicContact CG-CE1 3.96Å; P155-F274 HydrophobicContact CG-CG 4.28Å
156	Y	82.3	Confident	77.8	Confident	45 Å²	45	65.5 Å²	65.5	18%	0.176	36%	0.359	C	S	.	.	H	α-helix	trans	-51.2	-42.1	-176.3	-60.8	-77.8	0	0	0	113.4	L138 Y139 T142 V154 R158 I159 I160	L138-Y156 HydrophobicContact CB-CE1 4.25Å; Y139-Y156 WeakPolarHBondContact CA-OH 3.33Å; Y139-Y156 HydrophobicContact CD2-CE1 4.26Å; Y139-Y156 HydrophobicContact CD2-CE2 4.25Å; Y139-Y156 AromaticContact CD2-CZ 3.83Å; T142-Y156 PolarHBondContact OG1-OH 3.18Å; T142-Y156 VanDerWaalsContact OG1-OH 3.05Å; V154-Y156 VanDerWaalsContact C-N 3.26Å; V154-Y156 HydrophobicContact CB-CD2 4.31Å; V154-Y156 HydrophobicContact CB-CE1 4.1Å; V154-Y156 HydrophobicContact CB-CE2 3.72Å; V154-Y156 HydrophobicContact CG1-CD1 3.94Å; V154-Y156 HydrophobicContact CG1-CD2 4.37Å; V154-Y156 HydrophobicContact CG1-CE1 3.61Å; V154-Y156 HydrophobicContact CG1-CE2 4.07Å; V154-Y156 HydrophobicContact CG1-CG 4.3Å; V154-Y156 WeakPolarHBondContact O-CD2 3.39Å; V154-Y156 WeakPolarHBondContact O-CE2 3.44Å; V154-Y156 PolarHBondContact O-N 3.41Å; Y156-R158 VanDerWaalsContact C-N 3.34Å; Y156-R158 PolarHBondContact O-N 3.07Å; Y156-I159 PolarHBondContact O-N 2.99Å; Y156-I160 WeakPolarHBondContact O-CG1 3.31Å; Y156-I160 PolarHBondContact O-N 3.44Å
157	G	81.6	Confident	78.1	Confident	55 Å²	55	65.9 Å²	65.9	57%	0.567	36%	0.362	S	S	*	.	H	α-helix	trans	-61.7	-39.7	176.6	0	0	0	0	0	112.8	P155 L161	P155-G157 VanDerWaalsContact C-N 3.26Å; P155-G157 PolarHBondContact O-N 2.88Å; P155-G157 VanDerWaalsContact O-N 3.16Å; G157-L161 VanDerWaalsContact O-CB 3.3Å; G157-L161 WeakPolarHBondContact O-CB 2.84Å; G157-L161 PolarHBondContact O-N 3Å
158	R	82.4	Confident	78.9	Confident	141 Å²	141	63 Å²	63	53%	0.532	35%	0.346	S	S	.	.	H	α-helix	trans	-71.2	-33.4	175.7	-62.9	-172.2	177.5	-169.5	2	112.1	P155 Y156 L161 S162 A273	P155-R158 HydrophobicContact CB-CB 4.04Å; P155-R158 HydrophobicContact CB-CG 4.12Å; P155-R158 WeakPolarHBondContact O-CA 3.37Å; P155-R158 WeakPolarHBondContact O-CB 3.32Å; P155-R158 PolarHBondContact O-N 3.22Å; Y156-R158 VanDerWaalsContact C-N 3.34Å; Y156-R158 PolarHBondContact O-N 3.07Å; R158-L161 PolarHBondContact O-N 3.4Å; R158-S162 VanDerWaalsContact O-CB 3.26Å; R158-S162 WeakPolarHBondContact O-CB 3.32Å; R158-S162 PolarHBondContact O-N 3.29Å; R158-S162 PolarHBondContact O-OG 2.97Å; R158-A273 HydrophobicContact CB-CB 4.13Å; R158-A273 VanDerWaalsContact CD-O 3.23Å; R158-A273 WeakPolarHBondContact CD-O 3.02Å
159	I	84.8	Confident	79.9	Confident	0 Å²	0	60 Å²	60	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-64.9	-48.6	175.2	-63.3	174.5	0	0	0	110.1	L138 V154 P155 Y156 L161 S162 L163 I269 A273 F274	L138-I159 HydrophobicContact CD1-CD1 3.62Å; L138-I159 HydrophobicContact CD1-CG2 4.39Å; V154-I159 HydrophobicContact CG1-CD1 3.87Å; P155-I159 WeakPolarHBondContact O-CG1 3.26Å; P155-I159 PolarHBondContact O-N 3.15Å; Y156-I159 PolarHBondContact O-N 2.99Å; I159-L161 VanDerWaalsContact C-N 3.33Å; I159-L161 PolarHBondContact O-N 3.34Å; I159-S162 PolarHBondContact O-N 2.96Å; I159-S162 VanDerWaalsContact O-N 3.16Å; I159-L163 HydrophobicContact CG2-CD1 4.11Å; I159-L163 WeakPolarHBondContact O-CG 3.15Å; I159-L163 PolarHBondContact O-N 2.92Å; I159-I269 HydrophobicContact CG1-CG2 4.38Å; I159-I269 HydrophobicContact CG2-CG2 4.48Å; I159-A273 HydrophobicContact CG1-CB 3.8Å; I159-F274 HydrophobicContact CD1-CE2 4.23Å; I159-F274 HydrophobicContact CD1-CZ 3.85Å; I159-F274 HydrophobicContact CG1-CE2 4.45Å; I159-F274 HydrophobicContact CG1-CZ 4.49Å
160	I	85.7	Confident	81	Confident	73 Å²	73	54.5 Å²	54.5	37%	0.374	29%	0.285	S	S	.	.	H	α-helix	trans	-58.5	-47.6	174.9	-66.6	166.9	0	0	0	110.3	L131 P135 Y156 S162 L163 V164	L131-I160 HydrophobicContact CD1-CG2 4.28Å; P135-I160 HydrophobicContact CB-CD1 4.32Å; P135-I160 HydrophobicContact CB-CG1 4.11Å; P135-I160 HydrophobicContact CG-CD1 4.17Å; P135-I160 HydrophobicContact CG-CG1 3.48Å; P135-I160 VanDerWaalsContact CG-CG1 3.48Å; Y156-I160 WeakPolarHBondContact O-CG1 3.31Å; Y156-I160 PolarHBondContact O-N 3.44Å; I160-S162 VanDerWaalsContact C-N 3.26Å; I160-S162 PolarHBondContact O-N 3.19Å; I160-L163 PolarHBondContact O-N 2.97Å; I160-L163 VanDerWaalsContact O-N 3.1Å; I160-V164 PolarHBondContact O-N 3.46Å
161	L	84.6	Confident	82.1	Confident	124 Å²	124	56.4 Å²	56.4	65%	0.649	30%	0.297	S	S	*	.	H	α-helix	trans	-62.3	-33.3	178.5	-170.5	66.4	0	0	0	112.3	G157 R158 I159 L163 P165	G157-L161 VanDerWaalsContact O-CB 3.3Å; G157-L161 WeakPolarHBondContact O-CB 2.84Å; G157-L161 PolarHBondContact O-N 3Å; R158-L161 PolarHBondContact O-N 3.4Å; I159-L161 VanDerWaalsContact C-N 3.33Å; I159-L161 PolarHBondContact O-N 3.34Å; L161-L163 VanDerWaalsContact C-N 3.34Å; L161-P165 WeakPolarHBondContact O-CD 3.36Å
162	S	82.9	Confident	83.6	Confident	16 Å²	16	52.2 Å²	52.2	11%	0.112	28%	0.282	C	S	.	.	H	α-helix	trans	-75.2	-22.8	176.9	-58.3	0	0	0	0	113	R158 I159 I160 P165	R158-S162 VanDerWaalsContact O-CB 3.26Å; R158-S162 WeakPolarHBondContact O-CB 3.32Å; R158-S162 PolarHBondContact O-N 3.29Å; R158-S162 PolarHBondContact O-OG 2.97Å; I159-S162 PolarHBondContact O-N 2.96Å; I159-S162 VanDerWaalsContact O-N 3.16Å; I160-S162 VanDerWaalsContact C-N 3.26Å; I160-S162 PolarHBondContact O-N 3.19Å; S162-P165 WeakPolarHBondContact O-CD 3.35Å
163	L	84.9	Confident	84.8	Confident	4 Å²	4	44.9 Å²	44.9	2%	0.021	24%	0.243	C	C	.	.	H	α-helix	trans	-80.5	-27.8	175.9	-74.7	164.4	0	0	0	112.7	A130 L131 M134 P135 I159 I160 L161 V166 L167 L265 I269	A130-L163 HydrophobicContact CB-CD2 4.3Å; L131-L163 HydrophobicContact CD1-CB 3.87Å; M134-L163 HydrophobicContact CB-CD1 4.25Å; M134-L163 HydrophobicContact SD-CD1 4.15Å; M134-L163 HydrophobicContact SD-CD2 4.12Å; P135-L163 HydrophobicContact CG-CD1 4.46Å; I159-L163 HydrophobicContact CG2-CD1 4.11Å; I159-L163 WeakPolarHBondContact O-CG 3.15Å; I159-L163 PolarHBondContact O-N 2.92Å; I160-L163 PolarHBondContact O-N 2.97Å; I160-L163 VanDerWaalsContact O-N 3.1Å; L161-L163 VanDerWaalsContact C-N 3.34Å; L163-V166 VanDerWaalsContact O-CB 3.23Å; L163-V166 WeakPolarHBondContact O-CB 3.22Å; L163-V166 PolarHBondContact O-N 3.39Å; L163-L167 PolarHBondContact O-N 3Å; L163-L265 HydrophobicContact CD2-CD1 4.12Å; L163-L265 HydrophobicContact CD2-CD2 4.4Å; L163-I269 HydrophobicContact CD2-CD1 3.84Å; L163-I269 HydrophobicContact CG-CD1 4.16Å
164	V	83.4	Confident	85.8	Confident	61 Å²	61	42.2 Å²	42.2	37%	0.37	23%	0.232	S	C	.	.	H	α-helix	trans	-58.6	-46.4	177.5	172.8	0	0	0	0	112.5	L131 I160 V166 L167 I168	L131-V164 HydrophobicContact CD1-CG2 4.2Å; I160-V164 PolarHBondContact O-N 3.46Å; V164-V166 PolarHBondContact O-N 3.32Å; V164-V166 VanDerWaalsContact O-N 3.09Å; V164-L167 PolarHBondContact O-N 3.28Å; V164-L167 VanDerWaalsContact O-N 3.12Å; V164-I168 HydrophobicContact CG1-CD1 3.94Å; V164-I168 HydrophobicContact CG1-CG1 4.49Å; V164-I168 WeakPolarHBondContact O-CG1 3.42Å; V164-I168 PolarHBondContact O-N 2.85Å
165	P	80.9	Confident	86.5	Confident	61 Å²	61	46.1 Å²	46.1	40%	0.396	25%	0.252	S	S	.	.	H	α-helix	trans	-60.9	-12.6	173.1	-25	32.7	0	0	0	115.6	L161 S162 P169	L161-P165 WeakPolarHBondContact O-CD 3.36Å; S162-P165 WeakPolarHBondContact O-CD 3.35Å; P165-P169 WeakPolarHBondContact O-CD 3.01Å; P165-P169 WeakPolarHBondContact O-CG 3.39Å
166	V	85.2	Confident	87	Confident	2 Å²	2	47.5 Å²	47.5	1%	0.012	26%	0.257	C	S	.	.	H	α-helix	trans	-81.8	-43.2	173.9	178.9	0	0	0	0	110.2	L35 M39 T127 L163 V164 P169 C170 L265	L35-V166 HydrophobicContact CD2-CG2 3.86Å; L35-V166 HydrophobicContact CG-CG2 4.42Å; M39-V166 HydrophobicContact CG-CB 4.34Å; M39-V166 HydrophobicContact CG-CG1 3.59Å; M39-V166 HydrophobicContact SD-CG1 3.5Å; M39-V166 VanDerWaalsContact SD-CG1 3.5Å; T127-V166 HydrophobicContact CG2-CG1 3.91Å; L163-V166 VanDerWaalsContact O-CB 3.23Å; L163-V166 WeakPolarHBondContact O-CB 3.22Å; L163-V166 PolarHBondContact O-N 3.39Å; V164-V166 PolarHBondContact O-N 3.32Å; V164-V166 VanDerWaalsContact O-N 3.09Å; V166-P169 WeakPolarHBondContact O-CD 3.24Å; V166-P169 WeakPolarHBondContact O-CG 3.4Å; V166-C170 WeakPolarHBondContact O-CB 3.36Å; V166-C170 PolarHBondContact O-N 3.23Å; V166-L265 HydrophobicContact CB-CD1 4.29Å; V166-L265 HydrophobicContact CG1-CD1 3.62Å; V166-L265 HydrophobicContact CG2-CD1 3.81Å; V166-L265 HydrophobicContact CG2-CG 4.33Å
167	L	87.9	Confident	87.3	Confident	27 Å²	27	47.3 Å²	47.3	14%	0.141	26%	0.258	C	S	.	.	H	α-helix	trans	-71.7	-35.2	-175.7	-62.2	-176.7	0	0	0	112.8	T127 F128 L131 L163 V164 C170 T171	T127-L167 HydrophobicContact CG2-CD2 4.21Å; F128-L167 HydrophobicContact CD1-CD2 3.81Å; F128-L167 HydrophobicContact CE1-CD2 4.14Å; F128-L167 HydrophobicContact CG-CD2 4.24Å; L131-L167 HydrophobicContact CB-CD1 4.17Å; L131-L167 HydrophobicContact CD1-CD1 4.29Å; L131-L167 HydrophobicContact CD2-CD1 3.89Å; L131-L167 HydrophobicContact CG-CD1 4.35Å; L163-L167 PolarHBondContact O-N 3Å; V164-L167 PolarHBondContact O-N 3.28Å; V164-L167 VanDerWaalsContact O-N 3.12Å; L167-C170 PolarHBondContact O-N 3.11Å; L167-T171 VanDerWaalsContact O-CB 3.31Å; L167-T171 WeakPolarHBondContact O-CB 3.33Å; L167-T171 PolarHBondContact O-N 3.34Å; L167-T171 PolarHBondContact O-OG1 2.88Å
168	I	91.6	Very high	87.6	Confident	91 Å²	91	48.6 Å²	48.6	47%	0.467	26%	0.258	S	S	.	.	H	α-helix	trans	-58.2	-60.6	180	-65.8	166.7	0	0	0	111.8	V164 C170 T171 I172	V164-I168 HydrophobicContact CG1-CD1 3.94Å; V164-I168 HydrophobicContact CG1-CG1 4.49Å; V164-I168 WeakPolarHBondContact O-CG1 3.42Å; V164-I168 PolarHBondContact O-N 2.85Å; I168-C170 VanDerWaalsContact C-N 3.31Å; I168-C170 PolarHBondContact O-N 3.5Å; I168-T171 PolarHBondContact O-N 2.88Å; I168-I172 HydrophobicContact CG2-CD1 3.78Å; I168-I172 VanDerWaalsContact O-CG1 3.3Å; I168-I172 WeakPolarHBondContact O-CG1 3.23Å; I168-I172 PolarHBondContact O-N 3.06Å
169	P	91.6	Very high	88	Confident	1 Å²	1	49.5 Å²	49.5	1%	0.006	27%	0.265	C	S	.	.	H	α-helix	trans	-61.9	-36.8	178.5	20.8	-30.7	0	0	0	112.9	F36 M39 L40 P165 V166 T171 I172 G173	F36-P169 HydrophobicContact CD2-CB 3.62Å; F36-P169 HydrophobicContact CD2-CG 3.78Å; F36-P169 HydrophobicContact CE2-CB 3.7Å; F36-P169 HydrophobicContact CE2-CG 4.23Å; F36-P169 HydrophobicContact CG-CB 4.12Å; F36-P169 HydrophobicContact CG-CG 4.39Å; F36-P169 HydrophobicContact CZ-CB 4.24Å; F36-P169 WeakPolarHBondContact O-CB 3.33Å; M39-P169 HydrophobicContact CB-CB 4.1Å; M39-P169 HydrophobicContact CB-CG 3.71Å; L40-P169 HydrophobicContact CB-CB 4.12Å; L40-P169 WeakPolarHBondContact CD1-O 3.23Å; P165-P169 WeakPolarHBondContact O-CD 3.01Å; P165-P169 WeakPolarHBondContact O-CG 3.39Å; V166-P169 WeakPolarHBondContact O-CD 3.24Å; V166-P169 WeakPolarHBondContact O-CG 3.4Å; P169-T171 PolarHBondContact O-N 3.33Å; P169-I172 PolarHBondContact O-N 2.96Å; P169-G173 PolarHBondContact O-N 2.88Å
170	C	90.4	Very high	88.3	Confident	0 Å²	0	55.9 Å²	55.9	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-60.2	-46.6	175.3	-173.6	0	0	0	0	111.2	M39 G43 V166 L167 I168 G173 I174	M39-C170 HydrophobicContact CB-CB 4.42Å; M39-C170 WeakPolarHBondContact O-CA 3.38Å; G43-C170 WeakPolarHBondContact CA-O 3.48Å; V166-C170 WeakPolarHBondContact O-CB 3.36Å; V166-C170 PolarHBondContact O-N 3.23Å; L167-C170 PolarHBondContact O-N 3.11Å; I168-C170 VanDerWaalsContact C-N 3.31Å; I168-C170 PolarHBondContact O-N 3.5Å; C170-G173 PolarHBondContact O-N 3.49Å; C170-I174 WeakPolarHBondContact O-CG1 3.44Å; C170-I174 PolarHBondContact O-N 2.83Å
171	T	90.5	Very high	88.4	Confident	54 Å²	54	56 Å²	56	33%	0.331	30%	0.296	S	S	.	.	H	α-helix	trans	-65.1	-42.3	178.2	-55.6	0	0	0	0	111.4	L167 I168 P169 G173 I174 I175	L167-T171 VanDerWaalsContact O-CB 3.31Å; L167-T171 WeakPolarHBondContact O-CB 3.33Å; L167-T171 PolarHBondContact O-N 3.34Å; L167-T171 PolarHBondContact O-OG1 2.88Å; I168-T171 PolarHBondContact O-N 2.88Å; P169-T171 PolarHBondContact O-N 3.33Å; T171-G173 VanDerWaalsContact C-N 3.3Å; T171-G173 PolarHBondContact O-N 3.03Å; T171-I174 PolarHBondContact O-N 3.35Å; T171-I175 HydrophobicContact CG2-CD1 3.98Å; T171-I175 WeakPolarHBondContact O-CG1 3.22Å; T171-I175 PolarHBondContact O-N 3.02Å
172	I	92	Very high	88.6	Confident	80 Å²	80	55.9 Å²	55.9	41%	0.41	29%	0.291	S	S	.	.	H	α-helix	trans	-57.7	-45.4	173.9	-68.7	167.1	0	0	0	110.4	L40 I168 P169 I174 I175 L176	L40-I172 HydrophobicContact CD1-CB 4.24Å; L40-I172 HydrophobicContact CD1-CG2 3.87Å; I168-I172 HydrophobicContact CG2-CD1 3.78Å; I168-I172 VanDerWaalsContact O-CG1 3.3Å; I168-I172 WeakPolarHBondContact O-CG1 3.23Å; I168-I172 PolarHBondContact O-N 3.06Å; P169-I172 PolarHBondContact O-N 2.96Å; I172-I174 PolarHBondContact O-N 3.43Å; I172-I175 PolarHBondContact O-N 3.5Å; I172-L176 VanDerWaalsContact O-CB 3.24Å; I172-L176 WeakPolarHBondContact O-CB 3.49Å; I172-L176 PolarHBondContact O-N 3.25Å
173	G	91.1	Very high	88.8	Confident	0 Å²	0	60.6 Å²	60.6	0%	0	31%	0.307	C	S	.	.	H	α-helix	trans	-60.2	-44.3	178	0	0	0	0	0	112.7	G43 P169 C170 T171 L176 K177	G43-G173 CarbonylContact O-C 3.22Å; P169-G173 PolarHBondContact O-N 2.88Å; C170-G173 PolarHBondContact O-N 3.49Å; T171-G173 VanDerWaalsContact C-N 3.3Å; T171-G173 PolarHBondContact O-N 3.03Å; G173-L176 PolarHBondContact O-N 2.88Å; G173-K177 WeakPolarHBondContact O-CB 3.44Å; G173-K177 PolarHBondContact O-N 3.23Å
174	I	90.3	Very high	89	Confident	19 Å²	19	60.7 Å²	60.7	10%	0.097	31%	0.308	C	S	.	.	H	α-helix	trans	-61.3	-47	177	-66	164.5	0	0	0	110.7	G43 M46 T124 F128 C170 T171 I172 L176 K177 S178	G43-I174 WeakPolarHBondContact O-CA 3.35Å; G43-I174 PolarHBondContact O-N 2.87Å; M46-I174 HydrophobicContact CB-CG1 4.08Å; M46-I174 HydrophobicContact CG-CG1 4.16Å; T124-I174 HydrophobicContact CG2-CD1 4.15Å; F128-I174 HydrophobicContact CE2-CD1 4.03Å; F128-I174 HydrophobicContact CZ-CD1 4.25Å; C170-I174 WeakPolarHBondContact O-CG1 3.44Å; C170-I174 PolarHBondContact O-N 2.83Å; T171-I174 PolarHBondContact O-N 3.35Å; I172-I174 PolarHBondContact O-N 3.43Å; I174-L176 VanDerWaalsContact C-N 3.34Å; I174-L176 PolarHBondContact O-N 3.16Å; I174-K177 PolarHBondContact O-N 3.33Å; I174-S178 WeakPolarHBondContact O-CB 3.27Å; I174-S178 PolarHBondContact O-N 2.79Å
175	I	90.9	Very high	89.1	Confident	82 Å²	82	66.4 Å²	66.4	42%	0.421	32%	0.323	S	S	.	.	H	α-helix	trans	-63.5	-42.8	178.6	-67.2	168.6	0	0	0	110.5	T171 I172 S178 K179	T171-I175 HydrophobicContact CG2-CD1 3.98Å; T171-I175 WeakPolarHBondContact O-CG1 3.22Å; T171-I175 PolarHBondContact O-N 3.02Å; I172-I175 PolarHBondContact O-N 3.5Å; I175-S178 PolarHBondContact O-N 3.29Å; I175-K179 HydrophobicContact CG2-CD 3.98Å; I175-K179 HydrophobicContact CG2-CG 4.33Å; I175-K179 WeakPolarHBondContact O-CB 3.17Å; I175-K179 PolarHBondContact O-N 3.2Å
176	L	91.2	Very high	89.4	Confident	61 Å²	61	71.7 Å²	71.7	32%	0.319	34%	0.336	S	S	.	.	H	α-helix	trans	-66.2	-41.5	-178.3	-167.9	65.9	0	0	0	111.4	I172 G173 I174 S178 K179 R180 M184 V187	I172-L176 VanDerWaalsContact O-CB 3.24Å; I172-L176 WeakPolarHBondContact O-CB 3.49Å; I172-L176 PolarHBondContact O-N 3.25Å; G173-L176 PolarHBondContact O-N 2.88Å; I174-L176 VanDerWaalsContact C-N 3.34Å; I174-L176 PolarHBondContact O-N 3.16Å; L176-S178 VanDerWaalsContact C-N 3.34Å; L176-K179 PolarHBondContact O-N 3.18Å; L176-R180 CarbonylContact O-C 3.58Å; L176-R180 WeakPolarHBondContact O-CA 3.3Å; L176-R180 PolarHBondContact O-N 2.96Å; L176-M184 HydrophobicContact CB-CE 4.15Å; L176-M184 HydrophobicContact CD2-CE 3.62Å; L176-M184 HydrophobicContact CG-CE 3.43Å; L176-M184 VanDerWaalsContact CG-CE 3.43Å; L176-V187 HydrophobicContact CD2-CG2 4.21Å
177	K	90.1	Very high	89.5	Confident	42 Å²	42	73.5 Å²	73.5	18%	0.183	35%	0.347	C	S	.	.	H	α-helix	trans	-62.2	-40.3	172.2	174.1	60.7	177.8	-174.5	0	112	C44 M46 E47 G173 I174 M184	C44-K177 WeakPolarHBondContact O-CD 3.39Å; C44-K177 WeakPolarHBondContact O-CG 3.34Å; M46-K177 WeakPolarHBondContact O-CG 3.29Å; E47-K177 VanDerWaalsContact CG-CE 3.45Å; E47-K177 WeakPolarHBondContact OE1-CE 3.18Å; E47-K177 IonicContact OE1-NZ 3.12Å; E47-K177 PolarHBondContact OE1-NZ 2.78Å; E47-K177 VanDerWaalsContact OE1-NZ 3.12Å; G173-K177 WeakPolarHBondContact O-CB 3.44Å; G173-K177 PolarHBondContact O-N 3.23Å; I174-K177 PolarHBondContact O-N 3.33Å; K177-M184 WeakPolarHBondContact CA-SD 3.3Å; K177-M184 HydrophobicContact CB-CG 4.29Å; K177-M184 HydrophobicContact CB-SD 3.72Å; K177-M184 HydrophobicContact CD-CB 4.42Å; K177-M184 HydrophobicContact CD-CG 3.6Å; K177-M184 HydrophobicContact CD-SD 4.16Å; K177-M184 HydrophobicContact CG-SD 4.5Å
178	S	88.2	Confident	89.5	Confident	82 Å²	82	74.8 Å²	74.8	57%	0.573	35%	0.354	S	S	*	.	H	α-helix	trans	-69.2	-40.2	178.1	-171.9	0	0	0	0	113	I174 I175 L176	I174-S178 WeakPolarHBondContact O-CB 3.27Å; I174-S178 PolarHBondContact O-N 2.79Å; I175-S178 PolarHBondContact O-N 3.29Å; L176-S178 VanDerWaalsContact C-N 3.34Å
179	K	90	Very high	89.3	Confident	159 Å²	159	76.2 Å²	76.2	69%	0.691	36%	0.357	S	S	*	.	H	α-helix	trans	-87.4	-34.8	-175.3	-71.3	-171.8	176.1	-175.6	0	113.2	I175 L176	I175-K179 HydrophobicContact CG2-CD 3.98Å; I175-K179 HydrophobicContact CG2-CG 4.33Å; I175-K179 WeakPolarHBondContact O-CB 3.17Å; I175-K179 PolarHBondContact O-N 3.2Å; L176-K179 PolarHBondContact O-N 3.18Å
180	R	90.7	Very high	89.2	Confident	134 Å²	134	77.6 Å²	77.6	51%	0.506	37%	0.371	S	S	.	.			trans	-140.5	63.7	-171.8	-61.5	-66.6	-171.4	128.3	4.3	111.9	L176 Q182 Y183	L176-R180 CarbonylContact O-C 3.58Å; L176-R180 WeakPolarHBondContact O-CA 3.3Å; L176-R180 PolarHBondContact O-N 2.96Å; R180-Q182 PolarHBondContact O-N 3.32Å; R180-Q182 VanDerWaalsContact O-N 3.07Å; R180-Y183 HydrophobicContact CB-CD2 3.86Å; R180-Y183 HydrophobicContact CB-CE2 4.44Å; R180-Y183 HydrophobicContact CG-CD2 4.42Å; R180-Y183 PolarHBondContact O-N 2.98Å
181	P	87.9	Confident	89	Confident	77 Å²	77	77.8 Å²	77.8	50%	0.5	37%	0.373	S	S	.	.	G	3₁₀ helix	trans	-59	-26.3	-177.6	23.9	-34.3	0	0	0	113.6	Y183 M184	P181-Y183 VanDerWaalsContact C-N 3.29Å; P181-Y183 PolarHBondContact O-N 2.92Å; P181-M184 WeakPolarHBondContact O-CB 3.38Å; P181-M184 VanDerWaalsContact O-CG 3.25Å; P181-M184 WeakPolarHBondContact O-CG 3.38Å; P181-M184 PolarHBondContact O-N 2.82Å
182	Q	89.7	Confident	88.8	Confident	120 Å²	120	80.9 Å²	80.9	56%	0.561	39%	0.385	S	S	*	.	G	3₁₀ helix	trans	-60.2	-31.2	179.4	67.1	-171.2	12.6	0	0	114.3	R180	R180-Q182 PolarHBondContact O-N 3.32Å; R180-Q182 VanDerWaalsContact O-N 3.07Å
183	Y	87.1	Confident	88.6	Confident	115 Å²	115	82 Å²	82	45%	0.451	39%	0.391	S	S	.	.	G	3₁₀ helix	trans	-88.1	-8	-178.3	-62.7	-64.3	0	0	0	113.5	R180 P181 R185 Y186 V187	R180-Y183 HydrophobicContact CB-CD2 3.86Å; R180-Y183 HydrophobicContact CB-CE2 4.44Å; R180-Y183 HydrophobicContact CG-CD2 4.42Å; R180-Y183 PolarHBondContact O-N 2.98Å; P181-Y183 VanDerWaalsContact C-N 3.29Å; P181-Y183 PolarHBondContact O-N 2.92Å; Y183-R185 VanDerWaalsContact C-N 3.26Å; Y183-R185 PolarHBondContact O-N 2.86Å; Y183-Y186 PolarHBondContact O-N 2.62Å; Y183-V187 PolarHBondContact O-N 3.44Å
184	M	87.7	Confident	88.6	Confident	7 Å²	7	84.6 Å²	84.6	3%	0.034	40%	0.404	C	S	.	.	H	α-helix	trans	-62.9	-34.7	-169.8	-63.8	-64	97.9	0	0	112.7	C44 L176 K177 P181 Y186 V187 I188	C44-M184 HydrophobicContact CB-SD 3.84Å; L176-M184 HydrophobicContact CB-CE 4.15Å; L176-M184 HydrophobicContact CD2-CE 3.62Å; L176-M184 HydrophobicContact CG-CE 3.43Å; L176-M184 VanDerWaalsContact CG-CE 3.43Å; K177-M184 WeakPolarHBondContact CA-SD 3.3Å; K177-M184 HydrophobicContact CB-CG 4.29Å; K177-M184 HydrophobicContact CB-SD 3.72Å; K177-M184 HydrophobicContact CD-CB 4.42Å; K177-M184 HydrophobicContact CD-CG 3.6Å; K177-M184 HydrophobicContact CD-SD 4.16Å; K177-M184 HydrophobicContact CG-SD 4.5Å; P181-M184 WeakPolarHBondContact O-CB 3.38Å; P181-M184 VanDerWaalsContact O-CG 3.25Å; P181-M184 WeakPolarHBondContact O-CG 3.38Å; P181-M184 PolarHBondContact O-N 2.82Å; M184-Y186 VanDerWaalsContact C-N 3.27Å; M184-Y186 PolarHBondContact O-N 3.41Å; M184-V187 HydrophobicContact CE-CG2 4.19Å; M184-V187 PolarHBondContact O-N 3.5Å; M184-I188 WeakPolarHBondContact O-CB 3.46Å; M184-I188 VanDerWaalsContact O-CG1 3.25Å; M184-I188 WeakPolarHBondContact O-CG1 3.34Å; M184-I188 PolarHBondContact O-N 3.39Å
185	R	85.4	Confident	88.4	Confident	180 Å²	180	85.1 Å²	85.1	68%	0.679	41%	0.406	S	S	*	.	H	α-helix	trans	-61.6	-37.7	176.4	-165	177.3	-167.4	-169.6	3	112	Y183 K189	Y183-R185 VanDerWaalsContact C-N 3.26Å; Y183-R185 PolarHBondContact O-N 2.86Å; R185-K189 VanDerWaalsContact O-CB 3.3Å; R185-K189 WeakPolarHBondContact O-CB 3.21Å; R185-K189 VanDerWaalsContact O-CG 3.22Å; R185-K189 WeakPolarHBondContact O-CG 3.32Å; R185-K189 PolarHBondContact O-N 3.01Å; R185-K189 VanDerWaalsContact O-N 3.16Å
186	Y	88.3	Confident	88.2	Confident	172 Å²	172	86.5 Å²	86.5	68%	0.675	41%	0.414	S	S	*	.	H	α-helix	trans	-75.5	-43.4	178.7	-59.7	-80	0	0	0	111.3	Y183 M184 K189 G190	Y183-Y186 PolarHBondContact O-N 2.62Å; M184-Y186 VanDerWaalsContact C-N 3.27Å; M184-Y186 PolarHBondContact O-N 3.41Å; Y186-K189 PolarHBondContact O-N 2.71Å; Y186-G190 PolarHBondContact O-N 2.92Å
187	V	87.8	Confident	88.1	Confident	41 Å²	41	89.2 Å²	89.2	25%	0.248	43%	0.428	C	S	.	.	H	α-helix	trans	-61.2	-47.1	178	177.5	0	0	0	0	111.1	L176 Y183 M184 G191	L176-V187 HydrophobicContact CD2-CG2 4.21Å; Y183-V187 PolarHBondContact O-N 3.44Å; M184-V187 HydrophobicContact CE-CG2 4.19Å; M184-V187 PolarHBondContact O-N 3.5Å; V187-G191 PolarHBondContact O-N 3.45Å
188	I	86.5	Confident	87.9	Confident	54 Å²	54	88 Å²	88	28%	0.277	43%	0.425	S	S	.	.	H	α-helix	trans	-65.2	-44.7	178.7	-66.5	167.6	0	0	0	110.6	C44 T45 M184 G191 M192	C44-I188 HydrophobicContact CB-CD1 4.33Å; C44-I188 HydrophobicContact CB-CG1 4.09Å; T45-I188 HydrophobicContact CG2-CD1 4.11Å; M184-I188 WeakPolarHBondContact O-CB 3.46Å; M184-I188 VanDerWaalsContact O-CG1 3.25Å; M184-I188 WeakPolarHBondContact O-CG1 3.34Å; M184-I188 PolarHBondContact O-N 3.39Å; I188-G191 PolarHBondContact O-N 3.33Å; I188-M192 HydrophobicContact CG2-CG 4.47Å; I188-M192 VanDerWaalsContact O-CG 3.25Å; I188-M192 WeakPolarHBondContact O-CG 3.4Å; I188-M192 PolarHBondContact O-N 3.37Å
189	K	87.9	Confident	87.6	Confident	121 Å²	121	85.9 Å²	85.9	53%	0.526	41%	0.41	S	S	.	.	H	α-helix	trans	-62.5	-46.2	177.7	-80	-178.2	175.6	-169.4	0	112.5	R185 Y186 M192 I193	R185-K189 VanDerWaalsContact O-CB 3.3Å; R185-K189 WeakPolarHBondContact O-CB 3.21Å; R185-K189 VanDerWaalsContact O-CG 3.22Å; R185-K189 WeakPolarHBondContact O-CG 3.32Å; R185-K189 PolarHBondContact O-N 3.01Å; R185-K189 VanDerWaalsContact O-N 3.16Å; Y186-K189 PolarHBondContact O-N 2.71Å; K189-M192 PolarHBondContact O-N 2.97Å; K189-I193 WeakPolarHBondContact O-CG1 3.15Å; K189-I193 PolarHBondContact O-N 2.91Å
190	G	89	Confident	87.4	Confident	30 Å²	30	82.2 Å²	82.2	31%	0.309	40%	0.401	S	S	.	.	H	α-helix	trans	-63.1	-44.4	176.6	0	0	0	0	0	111.6	Y186 M192 I193 I194	Y186-G190 PolarHBondContact O-N 2.92Å; G190-M192 VanDerWaalsContact C-N 3.35Å; G190-M192 PolarHBondContact O-N 3.22Å; G190-I193 PolarHBondContact O-N 3.03Å; G190-I194 WeakPolarHBondContact O-CG1 3.24Å; G190-I194 PolarHBondContact O-N 3.46Å
191	G	86.4	Confident	87.1	Confident	3 Å²	3	77.5 Å²	77.5	3%	0.031	39%	0.391	C	S	.	.	H	α-helix	trans	-56.8	-45.9	174.8	0	0	0	0	0	112.3	V187 I188 I193 I194 I195	V187-G191 PolarHBondContact O-N 3.45Å; I188-G191 PolarHBondContact O-N 3.33Å; G191-I193 VanDerWaalsContact C-N 3.34Å; G191-I193 PolarHBondContact O-N 3.06Å; G191-I194 PolarHBondContact O-N 3.37Å; G191-I195 WeakPolarHBondContact O-CB 3.24Å; G191-I195 WeakPolarHBondContact O-CD1 3.29Å; G191-I195 WeakPolarHBondContact O-CG1 3.26Å; G191-I195 PolarHBondContact O-N 3.25Å
192	M	85.9	Confident	86.9	Confident	119 Å²	119	74.4 Å²	74.4	59%	0.586	37%	0.37	S	S	*	.	H	α-helix	trans	-59	-41.9	176.4	-74	-66.5	-63	0	0	112.8	I188 K189 G190 L196	I188-M192 HydrophobicContact CG2-CG 4.47Å; I188-M192 VanDerWaalsContact O-CG 3.25Å; I188-M192 WeakPolarHBondContact O-CG 3.4Å; I188-M192 PolarHBondContact O-N 3.37Å; K189-M192 PolarHBondContact O-N 2.97Å; G190-M192 VanDerWaalsContact C-N 3.35Å; G190-M192 PolarHBondContact O-N 3.22Å; M192-L196 WeakPolarHBondContact O-CB 3.42Å; M192-L196 PolarHBondContact O-N 3.16Å
193	I	89.3	Confident	86.3	Confident	104 Å²	104	72.8 Å²	72.8	53%	0.533	37%	0.369	S	S	.	.	H	α-helix	trans	-65.5	-44.9	177	-65.1	167.5	0	0	0	110.5	K189 G190 G191 L196 L197	K189-I193 WeakPolarHBondContact O-CG1 3.15Å; K189-I193 PolarHBondContact O-N 2.91Å; G190-I193 PolarHBondContact O-N 3.03Å; G191-I193 VanDerWaalsContact C-N 3.34Å; G191-I193 PolarHBondContact O-N 3.06Å; I193-L196 WeakPolarHBondContact O-CB 3.46Å; I193-L196 PolarHBondContact O-N 3.49Å; I193-L197 HydrophobicContact CG2-CD1 4.14Å; I193-L197 WeakPolarHBondContact O-CG 3.48Å; I193-L197 PolarHBondContact O-N 2.81Å
194	I	89.4	Confident	86.1	Confident	54 Å²	54	71 Å²	71	28%	0.277	37%	0.369	S	S	.	.	H	α-helix	trans	-62.2	-46.8	178.2	-67.1	167.3	0	0	0	110.5	F33 F37 G190 G191 L196 L197 C198	F33-I194 HydrophobicContact CE1-CG2 4.11Å; F37-I194 HydrophobicContact CD1-CD1 4.02Å; F37-I194 HydrophobicContact CD1-CG2 4.42Å; F37-I194 HydrophobicContact CD2-CG2 3.76Å; F37-I194 HydrophobicContact CE1-CD1 3.59Å; F37-I194 HydrophobicContact CE2-CG2 4.08Å; F37-I194 HydrophobicContact CG-CG2 3.98Å; F37-I194 HydrophobicContact CZ-CD1 3.89Å; F37-I194 HydrophobicContact CZ-CG2 4.49Å; G190-I194 WeakPolarHBondContact O-CG1 3.24Å; G190-I194 PolarHBondContact O-N 3.46Å; G191-I194 PolarHBondContact O-N 3.37Å; I194-L196 VanDerWaalsContact C-N 3.29Å; I194-L196 PolarHBondContact O-N 2.96Å; I194-L197 PolarHBondContact O-N 3.06Å; I194-C198 WeakPolarHBondContact O-CB 3.37Å; I194-C198 PolarHBondContact O-N 2.76Å; I194-C198 PolarHBondContact O-SG 3.48Å; I194-C198 VanDerWaalsContact O-SG 3.32Å
195	I	86.8	Confident	85.7	Confident	30 Å²	30	72.3 Å²	72.3	15%	0.154	38%	0.377	C	S	.	.	H	α-helix	trans	-58.7	-43	177.4	-68.8	162.8	0	0	0	110.3	M34 F37 V38 G191 C198 S199	M34-I195 HydrophobicContact CE-CG2 3.88Å; F37-I195 HydrophobicContact CB-CD1 4.33Å; F37-I195 HydrophobicContact CB-CG1 3.98Å; V38-I195 HydrophobicContact CB-CD1 4.44Å; V38-I195 HydrophobicContact CG2-CD1 3.71Å; V38-I195 HydrophobicContact CG2-CG1 3.88Å; V38-I195 HydrophobicContact CG2-CG2 4.2Å; G191-I195 WeakPolarHBondContact O-CB 3.24Å; G191-I195 WeakPolarHBondContact O-CD1 3.29Å; G191-I195 WeakPolarHBondContact O-CG1 3.26Å; G191-I195 PolarHBondContact O-N 3.25Å; I195-C198 PolarHBondContact O-N 2.93Å; I195-S199 WeakPolarHBondContact O-CB 3.4Å; I195-S199 PolarHBondContact O-N 2.93Å; I195-S199 PolarHBondContact O-OG 3.27Å
196	L	86.9	Confident	85.1	Confident	111 Å²	111	64 Å²	64	58%	0.581	35%	0.346	S	S	*	.	H	α-helix	trans	-61.2	-50.3	176.4	-177.9	65.9	0	0	0	111.3	M192 I193 I194 C198 S199 V200	M192-L196 WeakPolarHBondContact O-CB 3.42Å; M192-L196 PolarHBondContact O-N 3.16Å; I193-L196 WeakPolarHBondContact O-CB 3.46Å; I193-L196 PolarHBondContact O-N 3.49Å; I194-L196 VanDerWaalsContact C-N 3.29Å; I194-L196 PolarHBondContact O-N 2.96Å; L196-C198 PolarHBondContact O-N 3.48Å; L196-S199 PolarHBondContact O-N 3.47Å; L196-S199 PolarHBondContact O-OG 3.42Å; L196-V200 WeakPolarHBondContact O-CG2 3.26Å; L196-V200 PolarHBondContact O-N 2.84Å; L196-V200 VanDerWaalsContact O-N 3.1Å
197	L	89.1	Confident	84.5	Confident	118 Å²	118	58.8 Å²	58.8	62%	0.618	34%	0.338	S	S	*	.	H	α-helix	trans	-60.5	-45	178.2	-69.3	173	0	0	0	112	I193 I194 S199 V200 A201	I193-L197 HydrophobicContact CG2-CD1 4.14Å; I193-L197 WeakPolarHBondContact O-CG 3.48Å; I193-L197 PolarHBondContact O-N 2.81Å; I194-L197 PolarHBondContact O-N 3.06Å; L197-S199 VanDerWaalsContact C-N 3.33Å; L197-S199 PolarHBondContact O-N 3.11Å; L197-V200 PolarHBondContact O-N 3.36Å; L197-A201 PolarHBondContact O-N 2.91Å
198	C	86.4	Confident	84	Confident	16 Å²	16	62.3 Å²	62.3	11%	0.108	36%	0.355	C	S	.	.	H	α-helix	trans	-61.8	-40.3	175.7	-70.4	0	0	0	0	111.8	I30 M34 I194 I195 L196 V200 A201 V202	I30-C198 HydrophobicContact CG2-CB 4.01Å; M34-C198 HydrophobicContact CB-CB 3.83Å; M34-C198 HydrophobicContact CG-CB 3.9Å; M34-C198 HydrophobicContact SD-CB 4.01Å; I194-C198 WeakPolarHBondContact O-CB 3.37Å; I194-C198 PolarHBondContact O-N 2.76Å; I194-C198 PolarHBondContact O-SG 3.48Å; I194-C198 VanDerWaalsContact O-SG 3.32Å; I195-C198 PolarHBondContact O-N 2.93Å; L196-C198 PolarHBondContact O-N 3.48Å; C198-V200 VanDerWaalsContact C-N 3.34Å; C198-V200 PolarHBondContact O-N 2.86Å; C198-A201 PolarHBondContact O-N 2.94Å; C198-V202 WeakPolarHBondContact O-CB 3.37Å; C198-V202 VanDerWaalsContact O-CG2 3.26Å; C198-V202 WeakPolarHBondContact O-CG2 3.48Å; C198-V202 PolarHBondContact O-N 3.34Å
199	S	82	Confident	83.1	Confident	38 Å²	38	59.9 Å²	59.9	27%	0.266	34%	0.342	S	S	.	.	H	α-helix	trans	-63.2	-39.8	178.4	73.2	0	0	0	0	112.5	I195 L196 L197 T203	I195-S199 WeakPolarHBondContact O-CB 3.4Å; I195-S199 PolarHBondContact O-N 2.93Å; I195-S199 PolarHBondContact O-OG 3.27Å; L196-S199 PolarHBondContact O-N 3.47Å; L196-S199 PolarHBondContact O-OG 3.42Å; L197-S199 VanDerWaalsContact C-N 3.33Å; L197-S199 PolarHBondContact O-N 3.11Å; S199-T203 WeakPolarHBondContact O-CB 3.26Å; S199-T203 PolarHBondContact O-N 3.42Å; S199-T203 PolarHBondContact O-OG1 3.27Å
200	V	84.9	Confident	82	Confident	83 Å²	83	54.5 Å²	54.5	50%	0.503	32%	0.319	S	S	.	.	H	α-helix	trans	-64.9	-46.6	174.4	174.5	0	0	0	0	110.1	L196 L197 C198 V202 T203 V204	L196-V200 WeakPolarHBondContact O-CG2 3.26Å; L196-V200 PolarHBondContact O-N 2.84Å; L196-V200 VanDerWaalsContact O-N 3.1Å; L197-V200 PolarHBondContact O-N 3.36Å; C198-V200 VanDerWaalsContact C-N 3.34Å; C198-V200 PolarHBondContact O-N 2.86Å; V200-V202 PolarHBondContact O-N 3.12Å; V200-T203 PolarHBondContact O-N 3.23Å; V200-V204 HydrophobicContact CG1-CG2 4.42Å; V200-V204 VanDerWaalsContact O-CG2 3.29Å; V200-V204 WeakPolarHBondContact O-CG2 3.23Å; V200-V204 PolarHBondContact O-N 3.12Å
201	A	85.4	Confident	80.9	Confident	35 Å²	35	54.9 Å²	54.9	29%	0.289	32%	0.324	S	S	.	.	H	α-helix	trans	-60.6	-45.7	178.1	0	0	0	0	0	112.1	I30 L197 C198 T203 V204 L205	I30-A201 HydrophobicContact CD1-CB 4.31Å; L197-A201 PolarHBondContact O-N 2.91Å; C198-A201 PolarHBondContact O-N 2.94Å; A201-T203 VanDerWaalsContact C-N 3.32Å; A201-T203 PolarHBondContact O-N 3.09Å; A201-V204 PolarHBondContact O-N 3.14Å; A201-L205 WeakPolarHBondContact O-CB 3.24Å; A201-L205 PolarHBondContact O-N 2.75Å
202	V	82	Confident	79.6	Confident	11 Å²	11	63.6 Å²	63.6	7%	0.067	36%	0.361	C	S	.	.	H	α-helix	trans	-58.1	-46	175.3	169.4	0	0	0	0	110.1	I30 L31 C198 V200 V204 S206	I30-V202 HydrophobicContact CB-CG2 4.38Å; I30-V202 HydrophobicContact CG2-CG2 3.61Å; L31-V202 HydrophobicContact CD2-CG1 4.01Å; L31-V202 HydrophobicContact CD2-CG2 3.9Å; L31-V202 HydrophobicContact CG-CG2 4.36Å; C198-V202 WeakPolarHBondContact O-CB 3.37Å; C198-V202 VanDerWaalsContact O-CG2 3.26Å; C198-V202 WeakPolarHBondContact O-CG2 3.48Å; C198-V202 PolarHBondContact O-N 3.34Å; V200-V202 PolarHBondContact O-N 3.12Å; V202-V204 PolarHBondContact O-N 3.48Å; V202-S206 WeakPolarHBondContact O-CB 3.05Å; V202-S206 PolarHBondContact O-N 2.76Å; V202-S206 PolarHBondContact O-OG 2.64Å
203	T	78.1	Confident	78.5	Confident	87 Å²	87	59.4 Å²	59.4	53%	0.534	34%	0.343	S	S	.	.	H	α-helix	trans	-61.4	-44.6	-179.9	-56.4	0	0	0	0	111.7	S199 V200 A201 S206 A207	S199-T203 WeakPolarHBondContact O-CB 3.26Å; S199-T203 PolarHBondContact O-N 3.42Å; S199-T203 PolarHBondContact O-OG1 3.27Å; V200-T203 PolarHBondContact O-N 3.23Å; A201-T203 VanDerWaalsContact C-N 3.32Å; A201-T203 PolarHBondContact O-N 3.09Å; T203-S206 WeakPolarHBondContact O-CB 3.37Å; T203-A207 WeakPolarHBondContact O-CB 3.42Å; T203-A207 PolarHBondContact O-N 3.1Å
204	V	82.9	Confident	77.3	Confident	76 Å²	76	57.2 Å²	57.2	46%	0.461	33%	0.332	S	S	.	.	H	α-helix	trans	-67.1	-50.2	179.4	173.9	0	0	0	0	111.2	V200 A201 V202 S206 A207 I208	V200-V204 HydrophobicContact CG1-CG2 4.42Å; V200-V204 VanDerWaalsContact O-CG2 3.29Å; V200-V204 WeakPolarHBondContact O-CG2 3.23Å; V200-V204 PolarHBondContact O-N 3.12Å; A201-V204 PolarHBondContact O-N 3.14Å; V202-V204 PolarHBondContact O-N 3.48Å; V204-S206 VanDerWaalsContact C-N 3.27Å; V204-S206 PolarHBondContact O-N 3.05Å; V204-A207 PolarHBondContact O-N 2.9Å; V204-I208 HydrophobicContact CG1-CD1 3.88Å; V204-I208 WeakPolarHBondContact O-CG1 3.35Å; V204-I208 PolarHBondContact O-N 3.45Å
205	L	79.8	Confident	76	Confident	36 Å²	36	60.3 Å²	60.3	19%	0.188	35%	0.346	C	S	.	.	H	α-helix	trans	-62	-38.1	178.5	-116	63	0	0	0	111.7	A26 L27 I30 A201 I208 N209	A26-L205 HydrophobicContact CB-CD2 3.78Å; L27-L205 HydrophobicContact CB-CD2 4.13Å; L27-L205 HydrophobicContact CD1-CB 4.45Å; I30-L205 HydrophobicContact CD1-CD2 4.12Å; A201-L205 WeakPolarHBondContact O-CB 3.24Å; A201-L205 PolarHBondContact O-N 2.75Å; L205-I208 PolarHBondContact O-N 3.35Å; L205-N209 VanDerWaalsContact O-CB 3.27Å; L205-N209 WeakPolarHBondContact O-CB 3.5Å; L205-N209 VanDerWaalsContact O-CG 3.3Å; L205-N209 PolarHBondContact O-N 2.88Å; L205-N209 PolarHBondContact O-ND2 3.25Å
206	S	73.3	Confident	74.9	Confident	4 Å²	4	61.4 Å²	61.4	3%	0.028	35%	0.35	C	S	.	.	H	α-helix	trans	-60.8	-46.9	174.5	-73.1	0	0	0	0	112.4	V202 T203 V204 I208 N209 V210 F284	V202-S206 WeakPolarHBondContact O-CB 3.05Å; V202-S206 PolarHBondContact O-N 2.76Å; V202-S206 PolarHBondContact O-OG 2.64Å; T203-S206 WeakPolarHBondContact O-CB 3.37Å; V204-S206 VanDerWaalsContact C-N 3.27Å; V204-S206 PolarHBondContact O-N 3.05Å; S206-I208 VanDerWaalsContact C-N 3.3Å; S206-I208 PolarHBondContact O-N 3.22Å; S206-N209 PolarHBondContact O-N 3.12Å; S206-V210 WeakPolarHBondContact O-CB 3.34Å; S206-V210 PolarHBondContact O-N 3.17Å; S206-F284 WeakPolarHBondContact OG-CE1 3.38Å; S206-F284 WeakPolarHBondContact OG-CZ 3.14Å
207	A	74.6	Confident	73.8	Confident	63 Å²	63	56.1 Å²	56.1	52%	0.521	32%	0.323	S	S	.	.	H	α-helix	trans	-62.1	-38.8	176.6	0	0	0	0	0	111.9	T203 V204 G211	T203-A207 WeakPolarHBondContact O-CB 3.42Å; T203-A207 PolarHBondContact O-N 3.1Å; V204-A207 PolarHBondContact O-N 2.9Å; A207-G211 VanDerWaalsContact O-CA 3.24Å; A207-G211 WeakPolarHBondContact O-CA 3.34Å; A207-G211 PolarHBondContact O-N 3.3Å
208	I	76.7	Confident	72.8	Confident	115 Å²	115	54.1 Å²	54.1	59%	0.59	31%	0.311	S	S	*	.	H	α-helix	trans	-70.1	-45.6	177.4	-64.9	165.3	0	0	0	111.5	V204 L205 S206	V204-I208 HydrophobicContact CG1-CD1 3.88Å; V204-I208 WeakPolarHBondContact O-CG1 3.35Å; V204-I208 PolarHBondContact O-N 3.45Å; L205-I208 PolarHBondContact O-N 3.35Å; S206-I208 VanDerWaalsContact C-N 3.3Å; S206-I208 PolarHBondContact O-N 3.22Å
209	N	68.1	Low	72.7	Confident	4 Å²	4	55.4 Å²	55.4	2%	0.021	32%	0.318	C	S	.	.	H	α-helix	trans	-73.2	-41.2	-174.3	-78	-25.3	0	0	0	112.7	P15 T23 D24 L205 S206	P15-N209 WeakPolarHBondContact CG-O 3.45Å; T23-N209 WeakPolarHBondContact CB-OD1 3.06Å; T23-N209 PolarHBondContact O-ND2 3.18Å; T23-N209 PolarHBondContact OG1-OD1 2.99Å; D24-N209 VanDerWaalsContact OD1-CG 3.3Å; D24-N209 PolarHBondContact OD1-ND2 2.95Å; L205-N209 VanDerWaalsContact O-CB 3.27Å; L205-N209 WeakPolarHBondContact O-CB 3.5Å; L205-N209 VanDerWaalsContact O-CG 3.3Å; L205-N209 PolarHBondContact O-N 2.88Å; L205-N209 PolarHBondContact O-ND2 3.25Å; S206-N209 PolarHBondContact O-N 3.12Å
210	V	65.4	Low	72.9	Confident	7 Å²	7	58.4 Å²	58.4	4%	0.042	34%	0.337	C	S	.	.	H	α-helix	trans	-103.9	-23.5	-170.9	-175.4	0	0	0	0	112.1	F18 S206 K212 S213 I214 P281 F283 F284	F18-V210 HydrophobicContact CE2-CG2 3.78Å; F18-V210 HydrophobicContact CZ-CG2 4.07Å; S206-V210 WeakPolarHBondContact O-CB 3.34Å; S206-V210 PolarHBondContact O-N 3.17Å; V210-K212 PolarHBondContact O-N 3.5Å; V210-S213 VanDerWaalsContact O-CB 3.27Å; V210-S213 WeakPolarHBondContact O-CB 3.42Å; V210-S213 PolarHBondContact O-N 3.34Å; V210-I214 HydrophobicContact CG1-CB 4.47Å; V210-P281 HydrophobicContact CG1-CB 4.06Å; V210-F283 HydrophobicContact CG2-CE1 4.11Å; V210-F283 HydrophobicContact CG2-CZ 4.31Å; V210-F284 HydrophobicContact CB-CE2 3.76Å; V210-F284 HydrophobicContact CB-CZ 4.26Å; V210-F284 HydrophobicContact CG1-CE2 3.82Å; V210-F284 HydrophobicContact CG2-CE2 3.61Å; V210-F284 HydrophobicContact CG2-CZ 4.01Å
211	G	65.6	Low	73.2	Confident	39 Å²	39	58 Å²	58	40%	0.402	33%	0.332	S	S	.	.	G	3₁₀ helix	trans	49.4	-125.9	172.8	0	0	0	0	0	112.9	A207 S213 I214	A207-G211 VanDerWaalsContact O-CA 3.24Å; A207-G211 WeakPolarHBondContact O-CA 3.34Å; A207-G211 PolarHBondContact O-N 3.3Å; G211-S213 PolarHBondContact O-N 2.85Å; G211-I214 WeakPolarHBondContact O-CG2 3.37Å
212	K	59	Low	73.4	Confident	186 Å²	186	56.4 Å²	56.4	81%	0.809	32%	0.318	S	S	*	.	G	3₁₀ helix	trans	-68.2	-17.9	178.4	-65.2	-178.8	-179.2	177.7	0	113.9	V210 I214 M215	V210-K212 PolarHBondContact O-N 3.5Å; K212-I214 PolarHBondContact O-N 3.15Å; K212-M215 WeakPolarHBondContact O-CB 3.09Å; K212-M215 VanDerWaalsContact O-CG 3.31Å; K212-M215 WeakPolarHBondContact O-CG 3.46Å; K212-M215 PolarHBondContact O-N 3.18Å; K212-M215 VanDerWaalsContact O-N 3.14Å
213	S	63.1	Low	73.8	Confident	30 Å²	30	58.8 Å²	58.8	21%	0.21	33%	0.33	C	S	.	.	G	3₁₀ helix	trans	-71.5	-9.3	-178.4	-55.3	0	0	0	0	113.2	V210 G211 M215 F216	V210-S213 VanDerWaalsContact O-CB 3.27Å; V210-S213 WeakPolarHBondContact O-CB 3.42Å; V210-S213 PolarHBondContact O-N 3.34Å; G211-S213 PolarHBondContact O-N 2.85Å; S213-M215 PolarHBondContact O-N 2.91Å; S213-F216 VanDerWaalsContact O-CB 3.3Å; S213-F216 WeakPolarHBondContact O-CB 3.33Å; S213-F216 PolarHBondContact O-N 3.12Å; S213-F216 VanDerWaalsContact O-N 3.09Å
214	I	63.4	Low	74.6	Confident	59 Å²	59	56.3 Å²	56.3	30%	0.303	32%	0.318	S	S	.	.	H	α-helix	trans	-62.9	-23.8	170.3	-157.4	150.4	0	0	0	111.7	V210 G211 K212 F216 A217 M218 F284	V210-I214 HydrophobicContact CG1-CB 4.47Å; G211-I214 WeakPolarHBondContact O-CG2 3.37Å; K212-I214 PolarHBondContact O-N 3.15Å; I214-F216 PolarHBondContact O-N 2.89Å; I214-F216 VanDerWaalsContact O-N 3.16Å; I214-A217 WeakPolarHBondContact O-CB 3.48Å; I214-A217 PolarHBondContact O-N 3.16Å; I214-M218 HydrophobicContact CG1-CE 4.4Å; I214-M218 WeakPolarHBondContact O-CG 3.48Å; I214-M218 PolarHBondContact O-N 3.25Å; I214-F284 HydrophobicContact CD1-CD1 4.3Å; I214-F284 HydrophobicContact CD1-CD2 4.01Å; I214-F284 HydrophobicContact CD1-CE1 4.35Å; I214-F284 HydrophobicContact CD1-CE2 4.05Å; I214-F284 HydrophobicContact CD1-CG 4.13Å; I214-F284 HydrophobicContact CD1-CZ 4.23Å; I214-F284 HydrophobicContact CG1-CD2 4.08Å; I214-F284 HydrophobicContact CG1-CE2 4.4Å; I214-F284 HydrophobicContact CG1-CG 4.43Å
215	M	62.2	Low	75.2	Confident	118 Å²	118	52.7 Å²	52.7	58%	0.581	30%	0.296	S	S	*	.	H	α-helix	trans	-57.2	-28.1	173.3	-68.6	-176.8	65.7	0	0	112.5	K212 S213 M218 T219	K212-M215 WeakPolarHBondContact O-CB 3.09Å; K212-M215 VanDerWaalsContact O-CG 3.31Å; K212-M215 WeakPolarHBondContact O-CG 3.46Å; K212-M215 PolarHBondContact O-N 3.18Å; K212-M215 VanDerWaalsContact O-N 3.14Å; S213-M215 PolarHBondContact O-N 2.91Å; M215-M218 CarbonylContact O-C 3.38Å; M215-M218 WeakPolarHBondContact O-CA 3.44Å; M215-M218 WeakPolarHBondContact O-CB 3.26Å; M215-M218 PolarHBondContact O-N 3.01Å; M215-M218 VanDerWaalsContact O-N 3.09Å; M215-T219 PolarHBondContact O-N 3.16Å
216	F	64.5	Low	75.8	Confident	54 Å²	54	51 Å²	51	24%	0.237	29%	0.287	C	S	.	.	H	α-helix	trans	-65.6	-41.2	175.7	-171.1	-89.8	0	0	0	111.8	F12 S213 I214 M218 T219 P281 L282	F12-F216 HydrophobicContact CB-CE2 4.48Å; F12-F216 HydrophobicContact CD2-CD2 4.41Å; F12-F216 HydrophobicContact CD2-CG 4.48Å; S213-F216 VanDerWaalsContact O-CB 3.3Å; S213-F216 WeakPolarHBondContact O-CB 3.33Å; S213-F216 PolarHBondContact O-N 3.12Å; S213-F216 VanDerWaalsContact O-N 3.09Å; I214-F216 PolarHBondContact O-N 2.89Å; I214-F216 VanDerWaalsContact O-N 3.16Å; F216-M218 PolarHBondContact O-N 3.47Å; F216-T219 PolarHBondContact O-N 2.87Å; F216-T219 PolarHBondContact O-OG1 3.21Å; F216-P281 HydrophobicContact CB-CG 3.85Å; F216-P281 HydrophobicContact CD1-CG 3.64Å; F216-P281 HydrophobicContact CG-CG 4.04Å; F216-L282 HydrophobicContact CE1-CD2 4.29Å; F216-L282 HydrophobicContact CE1-CG 4.44Å
217	A	62.7	Low	76.9	Confident	0 Å²	0	52.3 Å²	52.3	0%	0	30%	0.297	C	S	.	.	H	α-helix	trans	-67.7	-22.1	172.9	0	0	0	0	0	112.1	I214 T219 L222 F284 L288	I214-A217 WeakPolarHBondContact O-CB 3.48Å; I214-A217 PolarHBondContact O-N 3.16Å; A217-T219 VanDerWaalsContact C-N 3.3Å; A217-T219 PolarHBondContact O-N 2.99Å; A217-L222 WeakPolarHBondContact O-CB 3.17Å; A217-F284 HydrophobicContact CB-CB 4.12Å; A217-L288 WeakPolarHBondContact O-CD1 3.38Å
218	M	69.1	Low	78	Confident	76 Å²	76	52.2 Å²	52.2	37%	0.374	29%	0.287	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.5	19.1	177.8	-56.7	-71.6	142	0	0	113.2	I214 M215 F216 I223 L288	I214-M218 HydrophobicContact CG1-CE 4.4Å; I214-M218 WeakPolarHBondContact O-CG 3.48Å; I214-M218 PolarHBondContact O-N 3.25Å; M215-M218 CarbonylContact O-C 3.38Å; M215-M218 WeakPolarHBondContact O-CA 3.44Å; M215-M218 WeakPolarHBondContact O-CB 3.26Å; M215-M218 PolarHBondContact O-N 3.01Å; M215-M218 VanDerWaalsContact O-N 3.09Å; F216-M218 PolarHBondContact O-N 3.47Å; M218-I223 HydrophobicContact CB-CD1 4.3Å; M218-I223 VanDerWaalsContact O-CD1 3.23Å; M218-I223 WeakPolarHBondContact O-CD1 3.32Å; M218-L288 HydrophobicContact CE-CD1 3.7Å; M218-L288 HydrophobicContact CE-CD2 3.37Å; M218-L288 HydrophobicContact CE-CG 3.54Å; M218-L288 HydrophobicContact SD-CD1 4.08Å; M218-L288 HydrophobicContact SD-CD2 3.62Å; M218-L288 HydrophobicContact SD-CG 4.24Å
219	T	83.6	Confident	79	Confident	42 Å²	42	46.8 Å²	46.8	26%	0.258	26%	0.259	S	S	.	.			trans	-60.8	140	173.9	-60.2	0	0	0	0	109.7	M215 F216 A217 L221 L222 I223	M215-T219 PolarHBondContact O-N 3.16Å; F216-T219 PolarHBondContact O-N 2.87Å; F216-T219 PolarHBondContact O-OG1 3.21Å; A217-T219 VanDerWaalsContact C-N 3.3Å; A217-T219 PolarHBondContact O-N 2.99Å; T219-L221 PolarHBondContact O-N 3.28Å; T219-L222 PolarHBondContact O-N 2.93Å; T219-I223 PolarHBondContact O-N 3.34Å
220	P	86.9	Confident	80.4	Confident	102 Å²	102	46.6 Å²	46.6	66%	0.662	26%	0.258	S	S	*	.	H	α-helix	trans	-51.3	-35.6	-177.3	-30.2	35.6	0	0	0	114.4	A224	P220-A224 VanDerWaalsContact O-CB 3.31Å; P220-A224 WeakPolarHBondContact O-CB 2.98Å; P220-A224 PolarHBondContact O-N 3.48Å
221	L	90.4	Very high	81.9	Confident	75 Å²	75	51 Å²	51	39%	0.393	28%	0.277	S	S	.	.	H	α-helix	trans	-67.1	-41.2	177.4	-61.3	172.5	0	0	0	112.6	F83 L85 T219 A224 T225	F83-L221 HydrophobicContact CB-CD2 4.15Å; F83-L221 HydrophobicContact CD1-CD2 4.23Å; F83-L221 HydrophobicContact CG-CD2 4.32Å; L85-L221 HydrophobicContact CD2-CB 3.83Å; L85-L221 HydrophobicContact CD2-CD1 4.28Å; T219-L221 PolarHBondContact O-N 3.28Å; L221-A224 PolarHBondContact O-N 3.03Å; L221-T225 WeakPolarHBondContact O-CB 3.42Å; L221-T225 PolarHBondContact O-N 2.97Å; L221-T225 PolarHBondContact O-OG1 3.1Å
222	L	89.4	Confident	83.4	Confident	0 Å²	0	51 Å²	51	0%	0	27%	0.268	C	S	.	.	H	α-helix	trans	-71.7	-36.5	177	-71.6	173.8	0	0	0	111.6	L85 E89 I93 A217 T219 T225 S226 L282 F285	L85-L222 HydrophobicContact CD1-CD2 4.44Å; E89-L222 HydrophobicContact CB-CD2 4.34Å; I93-L222 HydrophobicContact CG2-CD2 4.3Å; A217-L222 WeakPolarHBondContact O-CB 3.17Å; T219-L222 PolarHBondContact O-N 2.93Å; L222-T225 PolarHBondContact O-N 3.21Å; L222-S226 VanDerWaalsContact O-CB 3.31Å; L222-S226 WeakPolarHBondContact O-CB 3.45Å; L222-S226 PolarHBondContact O-N 3.3Å; L222-S226 PolarHBondContact O-OG 3.12Å; L222-L282 HydrophobicContact CD1-CD2 3.68Å; L222-L282 HydrophobicContact CD2-CD2 4.46Å; L222-F285 HydrophobicContact CD2-CD2 4.06Å; L222-F285 HydrophobicContact CD2-CE2 4.32Å
223	I	91.6	Very high	85.2	Confident	61 Å²	61	42.2 Å²	42.2	31%	0.313	23%	0.229	S	C	.	.	H	α-helix	trans	-61.8	-49.5	171.7	-64.9	178.7	0	0	0	110.2	M218 T219 T225 S226 S227 F292	M218-I223 HydrophobicContact CB-CD1 4.3Å; M218-I223 VanDerWaalsContact O-CD1 3.23Å; M218-I223 WeakPolarHBondContact O-CD1 3.32Å; T219-I223 PolarHBondContact O-N 3.34Å; I223-T225 VanDerWaalsContact C-N 3.32Å; I223-T225 PolarHBondContact O-N 2.9Å; I223-S226 WeakPolarHBondContact CA-OG 3.18Å; I223-S226 PolarHBondContact O-N 3.25Å; I223-S226 PolarHBondContact O-OG 2.73Å; I223-S227 PolarHBondContact O-N 2.79Å; I223-F292 HydrophobicContact CG2-CE2 3.95Å; I223-F292 HydrophobicContact CG2-CZ 3.68Å
224	A	94.3	Very high	86.9	Confident	35 Å²	35	40.9 Å²	40.9	29%	0.289	22%	0.22	S	C	.	.	H	α-helix	trans	-58.8	-44.2	176.1	0	0	0	0	0	111.8	F83 P220 L221 S227 L228	F83-A224 HydrophobicContact CE2-CB 4.16Å; F83-A224 HydrophobicContact CZ-CB 4.08Å; P220-A224 VanDerWaalsContact O-CB 3.31Å; P220-A224 WeakPolarHBondContact O-CB 2.98Å; P220-A224 PolarHBondContact O-N 3.48Å; L221-A224 PolarHBondContact O-N 3.03Å; A224-S227 PolarHBondContact O-N 3.32Å; A224-L228 WeakPolarHBondContact O-CB 3.21Å; A224-L228 VanDerWaalsContact O-CG 3.28Å; A224-L228 WeakPolarHBondContact O-CG 3.49Å; A224-L228 PolarHBondContact O-N 3.33Å
225	T	94.5	Very high	88.5	Confident	0 Å²	0	42.3 Å²	42.3	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-64.4	-45.6	178.6	-54.7	0	0	0	0	111.9	L79 F83 I93 L221 L222 I223 S227 L228 M229 F285	L79-T225 HydrophobicContact CB-CG2 4.1Å; L79-T225 HydrophobicContact CD1-CG2 4.12Å; F83-T225 WeakPolarHBondContact CD2-OG1 3.29Å; I93-T225 HydrophobicContact CB-CG2 4.32Å; I93-T225 HydrophobicContact CD1-CG2 3.76Å; I93-T225 HydrophobicContact CG2-CG2 4.01Å; L221-T225 WeakPolarHBondContact O-CB 3.42Å; L221-T225 PolarHBondContact O-N 2.97Å; L221-T225 PolarHBondContact O-OG1 3.1Å; L222-T225 PolarHBondContact O-N 3.21Å; I223-T225 VanDerWaalsContact C-N 3.32Å; I223-T225 PolarHBondContact O-N 2.9Å; T225-S227 VanDerWaalsContact C-N 3.28Å; T225-S227 PolarHBondContact O-N 3.04Å; T225-L228 PolarHBondContact O-N 2.94Å; T225-M229 HydrophobicContact CG2-CG 4.1Å; T225-M229 HydrophobicContact CG2-SD 3.97Å; T225-M229 WeakPolarHBondContact O-CB 3.26Å; T225-M229 WeakPolarHBondContact O-CG 3.23Å; T225-M229 PolarHBondContact O-N 3.24Å; T225-F285 HydrophobicContact CG2-CE2 4.42Å; T225-F285 HydrophobicContact CG2-CZ 4.3Å
226	S	94.1	Very high	90.1	Very high	0 Å²	0	40 Å²	40	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-67	-24.9	-179.9	55.7	0	0	0	0	113.8	L222 I223 P230 F292	L222-S226 VanDerWaalsContact O-CB 3.31Å; L222-S226 WeakPolarHBondContact O-CB 3.45Å; L222-S226 PolarHBondContact O-N 3.3Å; L222-S226 PolarHBondContact O-OG 3.12Å; I223-S226 WeakPolarHBondContact CA-OG 3.18Å; I223-S226 PolarHBondContact O-N 3.25Å; I223-S226 PolarHBondContact O-OG 2.73Å; S226-P230 WeakPolarHBondContact O-CD 3.34Å; S226-P230 WeakPolarHBondContact O-CG 3.24Å; S226-F292 WeakPolarHBondContact O-CB 3.45Å; S226-F292 WeakPolarHBondContact OG-CD2 3.12Å; S226-F292 WeakPolarHBondContact OG-CE2 3.5Å
227	S	96.1	Very high	91.6	Very high	33 Å²	33	37.4 Å²	37.4	23%	0.231	21%	0.206	C	C	.	.	H	α-helix	trans	-81.7	-45.2	168.8	-176.6	0	0	0	0	112.4	I223 A224 T225 M229 P230 F231 F292 E296	I223-S227 PolarHBondContact O-N 2.79Å; A224-S227 PolarHBondContact O-N 3.32Å; T225-S227 VanDerWaalsContact C-N 3.28Å; T225-S227 PolarHBondContact O-N 3.04Å; S227-M229 PolarHBondContact O-N 3.3Å; S227-P230 VanDerWaalsContact O-CD 3.25Å; S227-P230 WeakPolarHBondContact O-CD 3.12Å; S227-P230 WeakPolarHBondContact O-CG 3.22Å; S227-F231 WeakPolarHBondContact O-CB 3.29Å; S227-F231 PolarHBondContact O-N 3.44Å; S227-F292 VanDerWaalsContact CB-CD1 3.43Å; S227-E296 PolarHBondContact OG-OE1 3.37Å
228	L	97.3	Very high	93.2	Very high	61 Å²	61	42.1 Å²	42.1	32%	0.319	22%	0.224	S	C	.	.	H	α-helix	trans	-68.8	-36	-175.2	-73.9	172.2	0	0	0	113.3	L79 F83 A224 T225 F231 I232	L79-L228 HydrophobicContact CD1-CB 3.99Å; L79-L228 HydrophobicContact CD2-CB 4.35Å; L79-L228 HydrophobicContact CD2-CD1 4.12Å; F83-L228 HydrophobicContact CE2-CD1 3.91Å; F83-L228 HydrophobicContact CZ-CD1 3.6Å; A224-L228 WeakPolarHBondContact O-CB 3.21Å; A224-L228 VanDerWaalsContact O-CG 3.28Å; A224-L228 WeakPolarHBondContact O-CG 3.49Å; A224-L228 PolarHBondContact O-N 3.33Å; T225-L228 PolarHBondContact O-N 2.94Å; L228-F231 PolarHBondContact O-N 2.66Å; L228-I232 HydrophobicContact CB-CD1 4.19Å; L228-I232 VanDerWaalsContact O-CB 3.27Å; L228-I232 WeakPolarHBondContact O-CB 3.42Å; L228-I232 WeakPolarHBondContact O-CD1 3.37Å; L228-I232 WeakPolarHBondContact O-CG1 3.41Å; L228-I232 PolarHBondContact O-N 3.05Å
229	M	97.1	Very high	94.5	Very high	0 Å²	0	41.4 Å²	41.4	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-57.3	-57	179.5	-75	-176.5	67.1	0	0	113.4	M72 T75 A76 L79 I93 T225 S227 F231 I232 G233 F285 Y289	M72-M229 WeakPolarHBondContact CE-O 3.44Å; T75-M229 HydrophobicContact CG2-CG 4.32Å; A76-M229 HydrophobicContact CB-CE 3.6Å; A76-M229 HydrophobicContact CB-SD 4.22Å; L79-M229 HydrophobicContact CD1-CB 4.46Å; L79-M229 HydrophobicContact CD1-CG 3.51Å; I93-M229 HydrophobicContact CB-SD 4.12Å; T225-M229 HydrophobicContact CG2-CG 4.1Å; T225-M229 HydrophobicContact CG2-SD 3.97Å; T225-M229 WeakPolarHBondContact O-CB 3.26Å; T225-M229 WeakPolarHBondContact O-CG 3.23Å; T225-M229 PolarHBondContact O-N 3.24Å; S227-M229 PolarHBondContact O-N 3.3Å; M229-F231 VanDerWaalsContact C-N 3.33Å; M229-F231 PolarHBondContact O-N 3.25Å; M229-I232 PolarHBondContact O-N 3.09Å; M229-G233 PolarHBondContact O-N 3.25Å; M229-F285 HydrophobicContact SD-CE1 4.39Å; M229-F285 HydrophobicContact SD-CZ 4.04Å; M229-Y289 HydrophobicContact CB-CD2 4.26Å; M229-Y289 HydrophobicContact CB-CE2 3.6Å; M229-Y289 HydrophobicContact CE-CE2 4.18Å; M229-Y289 HydrophobicContact SD-CE2 4.44Å
230	P	97.1	Very high	95.1	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-61.3	-41.4	177.9	21	-29	0	0	0	111.8	S226 S227 I232 G233 F234 Y289 F292 Q293 E296	S226-P230 WeakPolarHBondContact O-CD 3.34Å; S226-P230 WeakPolarHBondContact O-CG 3.24Å; S227-P230 VanDerWaalsContact O-CD 3.25Å; S227-P230 WeakPolarHBondContact O-CD 3.12Å; S227-P230 WeakPolarHBondContact O-CG 3.22Å; P230-I232 PolarHBondContact O-N 3.16Å; P230-G233 CarbonylContact O-C 3.56Å; P230-G233 WeakPolarHBondContact O-CA 3.09Å; P230-G233 PolarHBondContact O-N 3.14Å; P230-G233 VanDerWaalsContact O-N 3.13Å; P230-F234 HydrophobicContact CB-CE2 4Å; P230-F234 WeakPolarHBondContact O-CD2 3.27Å; P230-F234 WeakPolarHBondContact O-CG 3.33Å; P230-F234 PolarHBondContact O-N 3.06Å; P230-Y289 WeakPolarHBondContact CA-OH 3.49Å; P230-Y289 HydrophobicContact CB-CE1 4.11Å; P230-Y289 HydrophobicContact CB-CE2 4.42Å; P230-Y289 HydrophobicContact CG-CE1 4.44Å; P230-Y289 HydrophobicContact CG-CE2 4.28Å; P230-F292 HydrophobicContact CG-CB 4.16Å; P230-Q293 HydrophobicContact CB-CB 3.73Å; P230-Q293 HydrophobicContact CG-CB 4.26Å; P230-E296 WeakPolarHBondContact CG-OE2 3.48Å
231	F	97.5	Very high	95.4	Very high	100 Å²	100	36.2 Å²	36.2	44%	0.439	19%	0.189	S	C	.	.	H	α-helix	trans	-58.1	-51.4	178.6	-179.7	-103.9	0	0	0	112.5	S227 L228 M229 G233 F234 L235 E296	S227-F231 WeakPolarHBondContact O-CB 3.29Å; S227-F231 PolarHBondContact O-N 3.44Å; L228-F231 PolarHBondContact O-N 2.66Å; M229-F231 VanDerWaalsContact C-N 3.33Å; M229-F231 PolarHBondContact O-N 3.25Å; F231-G233 VanDerWaalsContact C-N 3.26Å; F231-G233 PolarHBondContact O-N 3.19Å; F231-F234 PolarHBondContact O-N 3.19Å; F231-L235 HydrophobicContact CE1-CD2 4.41Å; F231-L235 WeakPolarHBondContact O-CB 3.46Å; F231-L235 PolarHBondContact O-N 2.96Å; F231-E296 VanDerWaalsContact CA-OE2 3.23Å; F231-E296 WeakPolarHBondContact CA-OE2 2.93Å; F231-E296 WeakPolarHBondContact CB-OE2 3.5Å; F231-E296 PolarHBondContact N-OE2 2.92Å
232	I	97.8	Very high	95.5	Very high	40 Å²	40	34 Å²	34	21%	0.205	18%	0.181	C	C	.	.	H	α-helix	trans	-61.2	-40	176.7	-69.3	167.4	0	0	0	109.8	T75 L79 L228 M229 P230 L235 L236	T75-I232 HydrophobicContact CG2-CB 3.9Å; T75-I232 HydrophobicContact CG2-CD1 3.79Å; T75-I232 HydrophobicContact CG2-CG1 4.46Å; T75-I232 HydrophobicContact CG2-CG2 3.66Å; T75-I232 WeakPolarHBondContact OG1-CG2 3.15Å; L79-I232 HydrophobicContact CD1-CD1 4.3Å; L79-I232 HydrophobicContact CD2-CD1 4.43Å; L228-I232 HydrophobicContact CB-CD1 4.19Å; L228-I232 VanDerWaalsContact O-CB 3.27Å; L228-I232 WeakPolarHBondContact O-CB 3.42Å; L228-I232 WeakPolarHBondContact O-CD1 3.37Å; L228-I232 WeakPolarHBondContact O-CG1 3.41Å; L228-I232 PolarHBondContact O-N 3.05Å; M229-I232 PolarHBondContact O-N 3.09Å; P230-I232 PolarHBondContact O-N 3.16Å; I232-L235 PolarHBondContact O-N 3.22Å; I232-L236 HydrophobicContact CG2-CD1 3.47Å; I232-L236 VanDerWaalsContact CG2-CD1 3.47Å; I232-L236 HydrophobicContact CG2-CG 3.91Å; I232-L236 VanDerWaalsContact O-CB 3.28Å; I232-L236 WeakPolarHBondContact O-CB 3.3Å; I232-L236 WeakPolarHBondContact O-CG 3.29Å; I232-L236 PolarHBondContact O-N 3.16Å
233	G	97.3	Very high	95.8	Very high	0 Å²	0	40 Å²	40	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-55.1	-54.4	172.9	0	0	0	0	0	114.5	M229 P230 F231 L235 G237 T258	M229-G233 PolarHBondContact O-N 3.25Å; P230-G233 CarbonylContact O-C 3.56Å; P230-G233 WeakPolarHBondContact O-CA 3.09Å; P230-G233 PolarHBondContact O-N 3.14Å; P230-G233 VanDerWaalsContact O-N 3.13Å; F231-G233 VanDerWaalsContact C-N 3.26Å; F231-G233 PolarHBondContact O-N 3.19Å; G233-L235 VanDerWaalsContact C-N 3.32Å; G233-L235 PolarHBondContact O-N 3.44Å; G233-G237 WeakPolarHBondContact O-CA 3.24Å; G233-G237 PolarHBondContact O-N 3.5Å; G233-T258 WeakPolarHBondContact O-CB 3.48Å; G233-T258 WeakPolarHBondContact O-CG2 3.48Å
234	F	97.3	Very high	95.8	Very high	3 Å²	3	43.1 Å²	43.1	1%	0.013	22%	0.224	C	C	.	.	H	α-helix	trans	-59.1	-46.2	177.7	-65	-51.5	0	0	0	110.8	P230 F231 Y238 S255 M256 E296 L300	P230-F234 HydrophobicContact CB-CE2 4Å; P230-F234 WeakPolarHBondContact O-CD2 3.27Å; P230-F234 WeakPolarHBondContact O-CG 3.33Å; P230-F234 PolarHBondContact O-N 3.06Å; F231-F234 PolarHBondContact O-N 3.19Å; F234-Y238 WeakPolarHBondContact O-CB 3.37Å; F234-Y238 PolarHBondContact O-N 3.33Å; F234-Y238 VanDerWaalsContact O-N 3.14Å; F234-S255 WeakPolarHBondContact CD1-O 3.32Å; F234-S255 WeakPolarHBondContact O-CB 3.43Å; F234-S255 PolarHBondContact O-OG 2.89Å; F234-M256 HydrophobicContact CD1-SD 3.93Å; F234-M256 HydrophobicContact CE1-SD 3.81Å; F234-E296 HydrophobicContact CD2-CB 4.32Å; F234-E296 HydrophobicContact CE2-CB 3.99Å; F234-L300 HydrophobicContact CB-CD1 3.62Å; F234-L300 HydrophobicContact CD1-CD1 4.26Å; F234-L300 HydrophobicContact CD2-CD1 3.74Å; F234-L300 HydrophobicContact CE2-CD1 4.48Å; F234-L300 HydrophobicContact CG-CD1 3.62Å
235	L	97.3	Very high	95.6	Very high	88 Å²	88	46.2 Å²	46.2	46%	0.461	24%	0.243	S	C	.	.	H	α-helix	trans	-65.9	-57.1	-177.6	179.1	62.1	0	0	0	111.9	F231 I232 G233 G237 Y238 V239	F231-L235 HydrophobicContact CE1-CD2 4.41Å; F231-L235 WeakPolarHBondContact O-CB 3.46Å; F231-L235 PolarHBondContact O-N 2.96Å; I232-L235 PolarHBondContact O-N 3.22Å; G233-L235 VanDerWaalsContact C-N 3.32Å; G233-L235 PolarHBondContact O-N 3.44Å; L235-G237 VanDerWaalsContact C-N 3.34Å; L235-G237 PolarHBondContact O-N 3.33Å; L235-Y238 WeakPolarHBondContact O-CB 3.17Å; L235-Y238 PolarHBondContact O-N 3.45Å; L235-Y238 VanDerWaalsContact O-N 3.15Å; L235-V239 HydrophobicContact CD1-CG2 4.39Å; L235-V239 WeakPolarHBondContact O-CG2 3.35Å; L235-V239 PolarHBondContact O-N 3.4Å
236	L	97	Very high	95.4	Very high	70 Å²	70	47.2 Å²	47.2	37%	0.366	25%	0.248	S	C	.	.	H	α-helix	trans	-70	-31.9	-176	-64.9	-174.7	0	0	0	111.9	I71 I232 Y238 V239 L240	I71-L236 HydrophobicContact CD1-CB 3.89Å; I71-L236 HydrophobicContact CG2-CB 3.77Å; I71-L236 HydrophobicContact CG2-CD1 3.79Å; I71-L236 HydrophobicContact CG2-CG 4.41Å; I232-L236 HydrophobicContact CG2-CD1 3.47Å; I232-L236 VanDerWaalsContact CG2-CD1 3.47Å; I232-L236 HydrophobicContact CG2-CG 3.91Å; I232-L236 VanDerWaalsContact O-CB 3.28Å; I232-L236 WeakPolarHBondContact O-CB 3.3Å; I232-L236 WeakPolarHBondContact O-CG 3.29Å; I232-L236 PolarHBondContact O-N 3.16Å; L236-Y238 VanDerWaalsContact C-N 3.31Å; L236-Y238 PolarHBondContact O-N 3.02Å; L236-V239 PolarHBondContact O-N 2.87Å; L236-L240 WeakPolarHBondContact O-CB 3.49Å; L236-L240 PolarHBondContact O-N 3.03Å
237	G	96.2	Very high	95.2	Very high	0 Å²	0	50.7 Å²	50.7	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-61.5	-39.8	170.2	0	0	0	0	0	112.2	G233 L235 S241	G233-G237 WeakPolarHBondContact O-CA 3.24Å; G233-G237 PolarHBondContact O-N 3.5Å; L235-G237 VanDerWaalsContact C-N 3.34Å; L235-G237 PolarHBondContact O-N 3.33Å; G237-S241 WeakPolarHBondContact O-CB 3.47Å; G237-S241 PolarHBondContact O-N 3.47Å; G237-S241 VanDerWaalsContact O-N 3.14Å; G237-S241 PolarHBondContact O-OG 2.87Å
238	Y	95.7	Very high	94.9	Very high	98 Å²	98	50.7 Å²	50.7	38%	0.384	27%	0.272	S	S	.	.	H	α-helix	trans	-67.2	-46.1	173.7	-170.1	-90.6	0	0	0	112.1	F234 L235 L236 S241 A242 R251 R252	F234-Y238 WeakPolarHBondContact O-CB 3.37Å; F234-Y238 PolarHBondContact O-N 3.33Å; F234-Y238 VanDerWaalsContact O-N 3.14Å; L235-Y238 WeakPolarHBondContact O-CB 3.17Å; L235-Y238 PolarHBondContact O-N 3.45Å; L235-Y238 VanDerWaalsContact O-N 3.15Å; L236-Y238 VanDerWaalsContact C-N 3.31Å; L236-Y238 PolarHBondContact O-N 3.02Å; Y238-S241 WeakPolarHBondContact CA-OG 3.4Å; Y238-S241 PolarHBondContact O-N 2.73Å; Y238-S241 PolarHBondContact O-OG 3.27Å; Y238-A242 WeakPolarHBondContact O-CB 3.33Å; Y238-A242 PolarHBondContact O-N 3.42Å; Y238-R251 HydrophobicContact CD2-CB 4.07Å; Y238-R251 HydrophobicContact CE2-CB 3.85Å; Y238-R252 HydrophobicContact CE2-CG 4.28Å
239	V	96.3	Very high	94.7	Very high	61 Å²	61	53.8 Å²	53.8	37%	0.37	28%	0.279	S	S	.	.	H	α-helix	trans	-63.5	-48.5	-179.7	172.1	0	0	0	0	110.8	L235 L236 S241 A242 L243	L235-V239 HydrophobicContact CD1-CG2 4.39Å; L235-V239 WeakPolarHBondContact O-CG2 3.35Å; L235-V239 PolarHBondContact O-N 3.4Å; L236-V239 PolarHBondContact O-N 2.87Å; V239-S241 VanDerWaalsContact C-N 3.33Å; V239-S241 PolarHBondContact O-N 3.12Å; V239-A242 WeakPolarHBondContact O-CA 3.47Å; V239-A242 WeakPolarHBondContact O-CB 3.31Å; V239-A242 PolarHBondContact O-N 2.98Å; V239-A242 VanDerWaalsContact O-N 3.08Å; V239-L243 HydrophobicContact CG1-CD1 4.09Å; V239-L243 HydrophobicContact CG1-CG 4.33Å; V239-L243 WeakPolarHBondContact O-CG 3.25Å; V239-L243 PolarHBondContact O-N 2.89Å
240	L	95.3	Very high	94.5	Very high	36 Å²	36	54.3 Å²	54.3	19%	0.188	28%	0.283	C	S	.	.	H	α-helix	trans	-58.7	-47	178.9	-170.9	72.3	0	0	0	110.7	I63 V66 A67 I71 L236 A242 L243 F244	I63-L240 HydrophobicContact CG2-CD2 4.27Å; I63-L240 HydrophobicContact CG2-CG 4.36Å; V66-L240 HydrophobicContact CG1-CD2 4.38Å; A67-L240 HydrophobicContact CB-CD2 3.91Å; I71-L240 HydrophobicContact CD1-CB 4.21Å; I71-L240 HydrophobicContact CD1-CD2 3.92Å; L236-L240 WeakPolarHBondContact O-CB 3.49Å; L236-L240 PolarHBondContact O-N 3.03Å; L240-A242 VanDerWaalsContact C-N 3.27Å; L240-A242 PolarHBondContact O-N 3.21Å; L240-L243 PolarHBondContact O-N 2.95Å; L240-F244 HydrophobicContact CD1-CD2 4.18Å; L240-F244 HydrophobicContact CD1-CE2 3.72Å; L240-F244 HydrophobicContact CG-CD2 4.14Å; L240-F244 HydrophobicContact CG-CE2 4.1Å; L240-F244 VanDerWaalsContact O-CD2 3.29Å; L240-F244 WeakPolarHBondContact O-CD2 3.38Å; L240-F244 PolarHBondContact O-N 2.97Å; L240-F244 VanDerWaalsContact O-N 3.16Å
241	S	93.8	Very high	94.4	Very high	0 Å²	0	57.6 Å²	57.6	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-65.6	-30.3	177.6	57.6	0	0	0	0	113.3	G237 Y238 V239 C245 L246 R251	G237-S241 WeakPolarHBondContact O-CB 3.47Å; G237-S241 PolarHBondContact O-N 3.47Å; G237-S241 VanDerWaalsContact O-N 3.14Å; G237-S241 PolarHBondContact O-OG 2.87Å; Y238-S241 WeakPolarHBondContact CA-OG 3.4Å; Y238-S241 PolarHBondContact O-N 2.73Å; Y238-S241 PolarHBondContact O-OG 3.27Å; V239-S241 VanDerWaalsContact C-N 3.33Å; V239-S241 PolarHBondContact O-N 3.12Å; S241-C245 PolarHBondContact O-N 3.28Å; S241-L246 VanDerWaalsContact CB-CD1 3.47Å; S241-L246 WeakPolarHBondContact O-CB 3.08Å; S241-L246 PolarHBondContact O-N 2.92Å; S241-R251 VanDerWaalsContact OG-CA 3.31Å; S241-R251 WeakPolarHBondContact OG-CA 3.44Å; S241-R251 WeakPolarHBondContact OG-CB 3.4Å
242	A	93.3	Very high	94.3	Very high	28 Å²	28	54.9 Å²	54.9	23%	0.231	28%	0.282	C	S	.	.	H	α-helix	trans	-69.2	-41.9	172.6	0	0	0	0	0	112.7	Y238 V239 L240 F244 C245	Y238-A242 WeakPolarHBondContact O-CB 3.33Å; Y238-A242 PolarHBondContact O-N 3.42Å; V239-A242 WeakPolarHBondContact O-CA 3.47Å; V239-A242 WeakPolarHBondContact O-CB 3.31Å; V239-A242 PolarHBondContact O-N 2.98Å; V239-A242 VanDerWaalsContact O-N 3.08Å; L240-A242 VanDerWaalsContact C-N 3.27Å; L240-A242 PolarHBondContact O-N 3.21Å; A242-F244 VanDerWaalsContact C-N 3.28Å; A242-F244 PolarHBondContact O-N 3.42Å; A242-C245 WeakPolarHBondContact O-CA 3.5Å; A242-C245 PolarHBondContact O-N 3.48Å
243	L	94.6	Very high	94.1	Very high	126 Å²	126	53 Å²	53	66%	0.66	27%	0.272	S	S	*	.	H	α-helix	trans	-62	-35.9	177.7	-70.3	173.1	0	0	0	112.3	V239 L240 C245	V239-L243 HydrophobicContact CG1-CD1 4.09Å; V239-L243 HydrophobicContact CG1-CG 4.33Å; V239-L243 WeakPolarHBondContact O-CG 3.25Å; V239-L243 PolarHBondContact O-N 2.89Å; L240-L243 PolarHBondContact O-N 2.95Å; L243-C245 PolarHBondContact O-N 3.3Å
244	F	92.3	Very high	94	Very high	127 Å²	127	53 Å²	53	56%	0.557	27%	0.272	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.6	15.7	173.7	-72.3	-75.6	0	0	0	113.8	I63 L240 A242 L246	I63-F244 HydrophobicContact CD1-CB 3.4Å; I63-F244 HydrophobicContact CD1-CD1 4.46Å; I63-F244 HydrophobicContact CD1-CD2 4.34Å; I63-F244 HydrophobicContact CD1-CG 3.85Å; I63-F244 HydrophobicContact CG1-CB 4.13Å; I63-F244 HydrophobicContact CG1-CD2 4.13Å; I63-F244 HydrophobicContact CG1-CG 4.06Å; I63-F244 HydrophobicContact CG2-CD2 4.26Å; L240-F244 HydrophobicContact CD1-CD2 4.18Å; L240-F244 HydrophobicContact CD1-CE2 3.72Å; L240-F244 HydrophobicContact CG-CD2 4.14Å; L240-F244 HydrophobicContact CG-CE2 4.1Å; L240-F244 VanDerWaalsContact O-CD2 3.29Å; L240-F244 WeakPolarHBondContact O-CD2 3.38Å; L240-F244 PolarHBondContact O-N 2.97Å; L240-F244 VanDerWaalsContact O-N 3.16Å; A242-F244 VanDerWaalsContact C-N 3.28Å; A242-F244 PolarHBondContact O-N 3.42Å; F244-L246 VanDerWaalsContact C-N 3.27Å; F244-L246 PolarHBondContact O-N 2.95Å; F244-L246 VanDerWaalsContact O-N 3.16Å
245	C	89.9	Confident	94	Very high	99 Å²	99	53.2 Å²	53.2	67%	0.669	27%	0.274	S	S	*	.	T	Hydrogen-bonded Turn	trans	55.3	34.3	172.9	-61.9	0	0	0	0	114.8	S241 A242 L243	S241-C245 PolarHBondContact O-N 3.28Å; A242-C245 WeakPolarHBondContact O-CA 3.5Å; A242-C245 PolarHBondContact O-N 3.48Å; L243-C245 PolarHBondContact O-N 3.3Å
246	L	89.5	Confident	93.9	Very high	21 Å²	21	49.1 Å²	49.1	11%	0.11	25%	0.253	C	S	.	.			trans	-63.2	157.4	172.9	-82.3	144.4	0	0	0	111.2	I63 S241 F244 C250 R251 V254	I63-L246 HydrophobicContact CB-CD1 4.16Å; I63-L246 HydrophobicContact CD1-CD1 3.49Å; I63-L246 VanDerWaalsContact CD1-CD1 3.49Å; I63-L246 HydrophobicContact CD1-CG 4.08Å; I63-L246 HydrophobicContact CG1-CD1 4.42Å; I63-L246 HydrophobicContact CG2-CD1 3.86Å; S241-L246 VanDerWaalsContact CB-CD1 3.47Å; S241-L246 WeakPolarHBondContact O-CB 3.08Å; S241-L246 PolarHBondContact O-N 2.92Å; F244-L246 VanDerWaalsContact C-N 3.27Å; F244-L246 PolarHBondContact O-N 2.95Å; F244-L246 VanDerWaalsContact O-N 3.16Å; L246-C250 HydrophobicContact CB-CB 4.13Å; L246-C250 HydrophobicContact CD2-CB 3.71Å; L246-R251 HydrophobicContact CB-CG 3.91Å; L246-R251 PolarHBondContact O-NE 3.42Å; L246-R251 PolarHBondContact O-NH2 3.47Å; L246-V254 HydrophobicContact CD1-CG2 4.37Å
247	N	90.6	Very high	93.8	Very high	73 Å²	73	45.9 Å²	45.9	39%	0.39	24%	0.236	S	C	.	.			trans	-66.8	153.3	174.3	-70.9	-17.2	0	0	0	111	R249 C250 R251	N247-R249 PolarHBondContact O-N 3.37Å; N247-R249 VanDerWaalsContact O-N 3.1Å; N247-C250 WeakPolarHBondContact O-CA 3.45Å; N247-C250 PolarHBondContact O-N 3.03Å; N247-R251 PolarHBondContact O-N 2.88Å
248	G	90.7	Very high	93.8	Very high	33 Å²	33	45.9 Å²	45.9	34%	0.34	24%	0.236	S	C	.	.	H	α-helix	trans	-55.1	-34.5	-176.6	0	0	0	0	0	114.2	R252	G248-R252 WeakPolarHBondContact O-CG 3.49Å; G248-R252 PolarHBondContact O-N 3.32Å; G248-R252 PolarHBondContact O-NH1 2.98Å; G248-R252 VanDerWaalsContact O-NH1 3.15Å
249	R	93.1	Very high	93.8	Very high	126 Å²	126	41.2 Å²	41.2	48%	0.475	22%	0.217	S	C	.	.	H	α-helix	trans	-62	-49.2	172.4	-73.3	-173.9	-93.6	-158.9	-10.7	111.7	G114 N247 R252 T253 E342	G114-R249 WeakPolarHBondContact CA-O 3.41Å; N247-R249 PolarHBondContact O-N 3.37Å; N247-R249 VanDerWaalsContact O-N 3.1Å; R249-R252 PolarHBondContact O-N 2.91Å; R249-T253 PolarHBondContact O-N 2.89Å; R249-T253 VanDerWaalsContact O-N 3.15Å; R249-T253 PolarHBondContact O-OG1 3.48Å; R249-E342 IonicContact CZ-OE2 2.79Å; R249-E342 IonicContact NH1-OE2 2.73Å; R249-E342 IonicContact NH2-OE2 3.99Å; R249-E342 PolarHBondContact NH2-OE2 2.99Å
250	C	91.7	Very high	93.7	Very high	12 Å²	12	38.3 Å²	38.3	8%	0.081	20%	0.2	C	C	.	.	H	α-helix	trans	-68.1	-37.2	-179.9	-54.4	0	0	0	0	112.3	L118 L246 N247 R252 T253 V254	L118-C250 HydrophobicContact CD2-CB 3.69Å; L246-C250 HydrophobicContact CB-CB 4.13Å; L246-C250 HydrophobicContact CD2-CB 3.71Å; N247-C250 WeakPolarHBondContact O-CA 3.45Å; N247-C250 PolarHBondContact O-N 3.03Å; C250-R252 VanDerWaalsContact C-N 3.33Å; C250-R252 PolarHBondContact O-N 3.25Å; C250-T253 WeakPolarHBondContact O-CB 3.47Å; C250-T253 PolarHBondContact O-N 3.44Å; C250-V254 WeakPolarHBondContact O-CG2 3.23Å; C250-V254 PolarHBondContact O-N 3.37Å
251	R	94.9	Very high	93.7	Very high	68 Å²	68	36.7 Å²	36.7	26%	0.257	19%	0.191	S	C	.	.	H	α-helix	trans	-59.3	-44.2	176.2	-65.9	-179.2	-163.7	176.7	5.9	112.2	Y238 S241 L246 N247 T253 V254 S255	Y238-R251 HydrophobicContact CD2-CB 4.07Å; Y238-R251 HydrophobicContact CE2-CB 3.85Å; S241-R251 VanDerWaalsContact OG-CA 3.31Å; S241-R251 WeakPolarHBondContact OG-CA 3.44Å; S241-R251 WeakPolarHBondContact OG-CB 3.4Å; L246-R251 HydrophobicContact CB-CG 3.91Å; L246-R251 PolarHBondContact O-NE 3.42Å; L246-R251 PolarHBondContact O-NH2 3.47Å; N247-R251 PolarHBondContact O-N 2.88Å; R251-T253 VanDerWaalsContact C-N 3.34Å; R251-V254 PolarHBondContact O-N 3.39Å; R251-S255 VanDerWaalsContact O-CB 3.32Å; R251-S255 WeakPolarHBondContact O-CB 3.31Å; R251-S255 PolarHBondContact O-N 3.03Å
252	R	95.2	Very high	93.7	Very high	44 Å²	44	37 Å²	37	17%	0.166	19%	0.193	C	C	.	.	H	α-helix	trans	-64.4	-39.7	175.8	-67.9	-173	-57.1	-94.3	7.2	111.5	M112 K113 Y238 G248 R249 C250 S255 M256	M112-R252 HydrophobicContact CB-CB 4.38Å; M112-R252 WeakPolarHBondContact O-CD 3.39Å; M112-R252 PolarHBondContact O-NE 3.24Å; K113-R252 PolarHBondContact O-NH2 2.87Å; Y238-R252 HydrophobicContact CE2-CG 4.28Å; G248-R252 WeakPolarHBondContact O-CG 3.49Å; G248-R252 PolarHBondContact O-N 3.32Å; G248-R252 PolarHBondContact O-NH1 2.98Å; G248-R252 VanDerWaalsContact O-NH1 3.15Å; R249-R252 PolarHBondContact O-N 2.91Å; C250-R252 VanDerWaalsContact C-N 3.33Å; C250-R252 PolarHBondContact O-N 3.25Å; R252-S255 WeakPolarHBondContact O-CB 3.33Å; R252-M256 WeakPolarHBondContact O-CG 3.37Å; R252-M256 PolarHBondContact O-N 2.9Å
253	T	95	Very high	93.6	Very high	0 Å²	0	35.9 Å²	35.9	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-61.9	-50.1	173.8	-58.9	0	0	0	0	112	D115 L118 M122 R249 C250 R251 S255 M256 E257	D115-T253 WeakPolarHBondContact CA-OG1 3.48Å; D115-T253 PolarHBondContact N-OG1 3.47Å; D115-T253 VanDerWaalsContact O-CG2 3.28Å; D115-T253 WeakPolarHBondContact O-CG2 3.15Å; D115-T253 PolarHBondContact O-OG1 3.46Å; L118-T253 HydrophobicContact CB-CG2 4.13Å; L118-T253 HydrophobicContact CD2-CG2 4.27Å; L118-T253 HydrophobicContact CG-CG2 4.15Å; M122-T253 HydrophobicContact SD-CG2 4.04Å; R249-T253 PolarHBondContact O-N 2.89Å; R249-T253 VanDerWaalsContact O-N 3.15Å; R249-T253 PolarHBondContact O-OG1 3.48Å; C250-T253 WeakPolarHBondContact O-CB 3.47Å; C250-T253 PolarHBondContact O-N 3.44Å; R251-T253 VanDerWaalsContact C-N 3.34Å; T253-S255 VanDerWaalsContact C-N 3.29Å; T253-S255 PolarHBondContact O-N 3.14Å; T253-M256 PolarHBondContact O-N 3.31Å; T253-E257 VanDerWaalsContact O-CB 3.3Å; T253-E257 WeakPolarHBondContact O-CB 3.34Å; T253-E257 PolarHBondContact O-N 3.48Å
254	V	95.3	Very high	93.4	Very high	0 Å²	0	30.6 Å²	30.6	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-62	-40	-179.8	176.7	0	0	0	0	111	A64 A67 M122 L246 C250 R251 E257 T258	A64-V254 HydrophobicContact CB-CG1 4.47Å; A64-V254 HydrophobicContact CB-CG2 4.34Å; A67-V254 HydrophobicContact CB-CG1 4.21Å; M122-V254 HydrophobicContact CE-CG2 3.54Å; M122-V254 HydrophobicContact SD-CG2 4.23Å; L246-V254 HydrophobicContact CD1-CG2 4.37Å; C250-V254 WeakPolarHBondContact O-CG2 3.23Å; C250-V254 PolarHBondContact O-N 3.37Å; R251-V254 PolarHBondContact O-N 3.39Å; V254-E257 PolarHBondContact O-N 3.15Å; V254-T258 WeakPolarHBondContact O-CB 3.33Å; V254-T258 PolarHBondContact O-N 3.42Å; V254-T258 PolarHBondContact O-OG1 3.4Å
255	S	96.3	Very high	93.3	Very high	8 Å²	8	24.5 Å²	24.5	6%	0.056	13%	0.129	C	C	.	.	H	α-helix	trans	-55.8	-55.8	172.9	176.8	0	0	0	0	111.5	F234 R251 R252 T253 E257 T258 G259	F234-S255 WeakPolarHBondContact CD1-O 3.32Å; F234-S255 WeakPolarHBondContact O-CB 3.43Å; F234-S255 PolarHBondContact O-OG 2.89Å; R251-S255 VanDerWaalsContact O-CB 3.32Å; R251-S255 WeakPolarHBondContact O-CB 3.31Å; R251-S255 PolarHBondContact O-N 3.03Å; R252-S255 WeakPolarHBondContact O-CB 3.33Å; T253-S255 VanDerWaalsContact C-N 3.29Å; T253-S255 PolarHBondContact O-N 3.14Å; S255-E257 VanDerWaalsContact C-N 3.33Å; S255-E257 PolarHBondContact O-N 3.07Å; S255-T258 PolarHBondContact O-N 3.42Å; S255-G259 PolarHBondContact O-N 3.29Å; S255-G259 VanDerWaalsContact O-N 3.1Å
256	M	96	Very high	93.4	Very high	1 Å²	1	19.8 Å²	19.8	1%	0.005	10%	0.097	C	C	.	.	H	α-helix	trans	-64.1	-37.9	-179.2	-67.2	-57.4	161.2	0	0	112.6	F108 M112 F234 R252 T253 C260 L300	F108-M256 HydrophobicContact CB-CB 4.19Å; F108-M256 HydrophobicContact CB-CG 3.9Å; F108-M256 HydrophobicContact CB-SD 3.69Å; F108-M256 HydrophobicContact CD2-SD 4.25Å; F108-M256 HydrophobicContact CG-SD 4.38Å; M112-M256 HydrophobicContact CE-CE 3.81Å; M112-M256 HydrophobicContact CG-CE 3.51Å; M112-M256 HydrophobicContact CG-CG 4.32Å; M112-M256 HydrophobicContact CG-SD 4.48Å; M112-M256 HydrophobicContact SD-CE 3.96Å; F234-M256 HydrophobicContact CD1-SD 3.93Å; F234-M256 HydrophobicContact CE1-SD 3.81Å; R252-M256 WeakPolarHBondContact O-CG 3.37Å; R252-M256 PolarHBondContact O-N 2.9Å; T253-M256 PolarHBondContact O-N 3.31Å; M256-C260 VanDerWaalsContact O-CB 3.24Å; M256-C260 WeakPolarHBondContact O-CB 3.44Å; M256-C260 PolarHBondContact O-N 3.36Å; M256-C260 VanDerWaalsContact O-N 3.13Å; M256-C260 PolarHBondContact O-SG 2.87Å; M256-C260 VanDerWaalsContact O-SG 3.41Å; M256-L300 HydrophobicContact CE-CB 3.83Å; M256-L300 HydrophobicContact CE-CD1 3.92Å
257	E	95	Very high	93.4	Very high	2 Å²	2	19 Å²	19	1%	0.009	9%	0.093	C	C	.	.	H	α-helix	trans	-64.4	-45.8	176.4	-169.6	67.6	-166.2	0	0	111.9	Q68 S105 S119 M122 T123 T253 V254 S255	Q68-E257 PolarHBondContact OE1-O 2.85Å; S105-E257 WeakPolarHBondContact CB-OE2 3.44Å; S105-E257 PolarHBondContact OG-OE2 2.96Å; S119-E257 PolarHBondContact OG-OE2 3.44Å; M122-E257 HydrophobicContact CB-CG 3.75Å; M122-E257 HydrophobicContact SD-CB 4.31Å; M122-E257 HydrophobicContact SD-CG 4.26Å; T123-E257 WeakPolarHBondContact CA-OE1 3.25Å; T123-E257 WeakPolarHBondContact CB-OE1 3.47Å; T123-E257 PolarHBondContact N-OE1 3.43Å; T123-E257 VanDerWaalsContact OG1-CD 3.25Å; T123-E257 PolarHBondContact OG1-OE1 3.27Å; T123-E257 PolarHBondContact OG1-OE2 3.24Å; T123-E257 VanDerWaalsContact OG1-OE2 3.05Å; T253-E257 VanDerWaalsContact O-CB 3.3Å; T253-E257 WeakPolarHBondContact O-CB 3.34Å; T253-E257 PolarHBondContact O-N 3.48Å; V254-E257 PolarHBondContact O-N 3.15Å; S255-E257 VanDerWaalsContact C-N 3.33Å; S255-E257 PolarHBondContact O-N 3.07Å
258	T	95.7	Very high	93.3	Very high	0 Å²	0	15.8 Å²	15.8	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-64.8	-47.4	-177.1	-52.8	0	0	0	0	110.3	A67 I71 M72 G233 V254 S255	A67-T258 HydrophobicContact CB-CG2 4.09Å; A67-T258 VanDerWaalsContact CB-OG1 3.3Å; A67-T258 WeakPolarHBondContact CB-OG1 3.4Å; I71-T258 HydrophobicContact CB-CG2 4.39Å; I71-T258 HydrophobicContact CD1-CG2 4.45Å; I71-T258 HydrophobicContact CG2-CG2 4.47Å; M72-T258 WeakPolarHBondContact CE-O 3.49Å; M72-T258 HydrophobicContact CG-CG2 4.1Å; M72-T258 WeakPolarHBondContact CG-O 3.47Å; G233-T258 WeakPolarHBondContact O-CB 3.48Å; G233-T258 WeakPolarHBondContact O-CG2 3.48Å; V254-T258 WeakPolarHBondContact O-CB 3.33Å; V254-T258 PolarHBondContact O-N 3.42Å; V254-T258 PolarHBondContact O-OG1 3.4Å; S255-T258 PolarHBondContact O-N 3.42Å
259	G	94.9	Very high	93.2	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-69.5	-31	-177.9	0	0	0	0	0	114.8	M72 S255 Q261 Y289	M72-G259 VanDerWaalsContact CE-CA 3.44Å; S255-G259 PolarHBondContact O-N 3.29Å; S255-G259 VanDerWaalsContact O-N 3.1Å; G259-Q261 PolarHBondContact O-N 2.72Å; G259-Y289 PolarHBondContact O-OH 3.44Å
260	C	95.6	Very high	93	Very high	0 Å²	0	8.3 Å²	8.3	0%	0	4%	0.038	C	C	.	.			trans	-89.6	110	-178	-73.4	0	0	0	0	112.1	G101 G102 F108 M256	G101-C260 WeakPolarHBondContact CA-O 3.33Å; G102-C260 PolarHBondContact N-O 2.88Å; F108-C260 VanDerWaalsContact CD2-SG 3.57Å; M256-C260 VanDerWaalsContact O-CB 3.24Å; M256-C260 WeakPolarHBondContact O-CB 3.44Å; M256-C260 PolarHBondContact O-N 3.36Å; M256-C260 VanDerWaalsContact O-N 3.13Å; M256-C260 PolarHBondContact O-SG 2.87Å; M256-C260 VanDerWaalsContact O-SG 3.41Å
261	Q	95.3	Very high	92.7	Very high	3 Å²	3	9 Å²	9	1%	0.014	4%	0.04	C	C	.	.	B	Isolated β-bridge	trans	-92	155.1	176.9	-68.9	-65.5	-11.6	0	0	112.2	Q68 S99 P100 G259 V263 Y289 Q293	Q68-Q261 VanDerWaalsContact NE2-CD 3.33Å; S99-Q261 VanDerWaalsContact C-OE1 3.27Å; S99-Q261 PolarHBondContact O-OE1 3.02Å; P100-Q261 PolarHBondContact O-OE1 2.92Å; G259-Q261 PolarHBondContact O-N 2.72Å; Q261-V263 VanDerWaalsContact C-N 3.26Å; Q261-V263 PolarHBondContact O-N 3.24Å; Q261-Y289 HydrophobicContact CB-CD1 4.39Å; Q261-Y289 HydrophobicContact CB-CE1 3.75Å; Q261-Y289 HydrophobicContact CG-CE1 3.93Å; Q261-Y289 HydrophobicContact CG-CE2 4.29Å; Q261-Y289 WeakPolarHBondContact CG-OH 3.46Å; Q261-Q293 VanDerWaalsContact N-OE1 3.14Å
262	N	93.6	Very high	92.3	Very high	6 Å²	6	8.7 Å²	8.7	3%	0.032	5%	0.046	C	C	.	.			trans	-75.7	80.3	171.2	-164.7	-26.4	0	0	0	111.1	M39 P100 Q264 L265 C266	M39-N262 WeakPolarHBondContact CE-ND2 3.38Å; P100-N262 HydrophobicContact CG-CB 4.22Å; P100-N262 VanDerWaalsContact O-CB 3.23Å; P100-N262 WeakPolarHBondContact O-CB 3.48Å; P100-N262 PolarHBondContact O-N 2.83Å; N262-Q264 VanDerWaalsContact C-N 3.27Å; N262-Q264 PolarHBondContact O-N 3.2Å; N262-L265 HydrophobicContact CB-CB 4.01Å; N262-L265 VanDerWaalsContact CG-CB 3.45Å; N262-L265 PolarHBondContact O-N 2.89Å; N262-L265 WeakPolarHBondContact OD1-CB 3.42Å; N262-L265 PolarHBondContact OD1-N 3.32Å; N262-L265 VanDerWaalsContact OD1-N 3.16Å; N262-C266 PolarHBondContact O-N 2.64Å
263	V	91.1	Very high	91.8	Very high	4 Å²	4	6.6 Å²	6.6	2%	0.024	4%	0.038	C	C	.	.	H	α-helix	trans	-54.1	-43.2	-178.5	166	0	0	0	0	112.3	Q261 L265 C266 S267 P286 L287 Y289 M290	Q261-V263 VanDerWaalsContact C-N 3.26Å; Q261-V263 PolarHBondContact O-N 3.24Å; V263-L265 PolarHBondContact O-N 3.24Å; V263-C266 PolarHBondContact O-N 3.39Å; V263-S267 PolarHBondContact O-N 3.23Å; V263-S267 PolarHBondContact O-OG 2.89Å; V263-P286 HydrophobicContact CB-CB 4.4Å; V263-P286 HydrophobicContact CG1-CB 3.68Å; V263-P286 WeakPolarHBondContact CG1-O 3.37Å; V263-P286 WeakPolarHBondContact CG2-O 3.24Å; V263-L287 HydrophobicContact CG1-CD2 4.43Å; V263-Y289 HydrophobicContact CG2-CD1 4.04Å; V263-M290 HydrophobicContact CB-CE 3.89Å; V263-M290 HydrophobicContact CG1-CB 4.19Å; V263-M290 HydrophobicContact CG1-CE 3.45Å; V263-M290 VanDerWaalsContact CG1-CE 3.45Å; V263-M290 HydrophobicContact CG2-CB 4.06Å
264	Q	89.1	Confident	91.3	Very high	15 Å²	15	6.8 Å²	6.8	7%	0.07	4%	0.039	C	C	.	.	H	α-helix	trans	-64.2	-43.9	-177.5	-169.1	65.2	22	0	0	111.4	L31 M34 L35 V38 N262 C266 S267 T268	L31-Q264 PolarHBondContact O-NE2 3.07Å; M34-Q264 PolarHBondContact SD-NE2 3.19Å; L35-Q264 HydrophobicContact CB-CG 4.05Å; L35-Q264 HydrophobicContact CD1-CB 4.22Å; L35-Q264 HydrophobicContact CD1-CG 3.91Å; V38-Q264 HydrophobicContact CG2-CG 4.35Å; N262-Q264 VanDerWaalsContact C-N 3.27Å; N262-Q264 PolarHBondContact O-N 3.2Å; Q264-C266 VanDerWaalsContact C-N 3.34Å; Q264-S267 PolarHBondContact O-N 2.82Å; Q264-T268 PolarHBondContact O-N 3.21Å; Q264-T268 PolarHBondContact O-OG1 3.23Å; Q264-T268 VanDerWaalsContact O-OG1 3.07Å
265	L	90.2	Very high	90.6	Very high	0 Å²	0	9.1 Å²	9.1	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-62.3	-44.5	175.9	178.2	150.7	0	0	0	110.8	L35 P100 M134 L163 V166 N262 V263 T268 I269	L35-L265 HydrophobicContact CD1-CB 4.05Å; P100-L265 HydrophobicContact CG-CD1 3.92Å; M134-L265 HydrophobicContact SD-CD2 4.32Å; L163-L265 HydrophobicContact CD2-CD1 4.12Å; L163-L265 HydrophobicContact CD2-CD2 4.4Å; V166-L265 HydrophobicContact CB-CD1 4.29Å; V166-L265 HydrophobicContact CG1-CD1 3.62Å; V166-L265 HydrophobicContact CG2-CD1 3.81Å; V166-L265 HydrophobicContact CG2-CG 4.33Å; N262-L265 HydrophobicContact CB-CB 4.01Å; N262-L265 VanDerWaalsContact CG-CB 3.45Å; N262-L265 PolarHBondContact O-N 2.89Å; N262-L265 WeakPolarHBondContact OD1-CB 3.42Å; N262-L265 PolarHBondContact OD1-N 3.32Å; N262-L265 VanDerWaalsContact OD1-N 3.16Å; V263-L265 PolarHBondContact O-N 3.24Å; L265-T268 PolarHBondContact O-N 3.36Å; L265-I269 HydrophobicContact CD2-CD1 3.43Å; L265-I269 VanDerWaalsContact CD2-CD1 3.43Å; L265-I269 HydrophobicContact CD2-CG1 4.35Å; L265-I269 HydrophobicContact CG-CD1 4.03Å; L265-I269 WeakPolarHBondContact O-CG1 3.26Å; L265-I269 PolarHBondContact O-N 2.99Å
266	C	92.4	Very high	89.5	Confident	0 Å²	0	10.8 Å²	10.8	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-60.1	-49.5	177.5	-175.4	0	0	0	0	112.1	C96 N262 V263 Q264 T268 I269 L270 P286	C96-C266 WeakPolarHBondContact CA-SG 3.49Å; C96-C266 VanDerWaalsContact CB-SG 3.55Å; C96-C266 PolarHBondContact N-SG 2.83Å; N262-C266 PolarHBondContact O-N 2.64Å; V263-C266 PolarHBondContact O-N 3.39Å; Q264-C266 VanDerWaalsContact C-N 3.34Å; C266-T268 VanDerWaalsContact C-N 3.33Å; C266-T268 PolarHBondContact O-N 3.38Å; C266-I269 PolarHBondContact O-N 3.05Å; C266-L270 WeakPolarHBondContact O-CG 3.3Å; C266-L270 PolarHBondContact O-N 2.99Å; C266-P286 HydrophobicContact CB-CB 4.13Å; C266-P286 HydrophobicContact CB-CG 3.93Å; C266-P286 WeakPolarHBondContact SG-CG 3.46Å
267	S	89.1	Confident	88.4	Confident	4 Å²	4	15.7 Å²	15.7	3%	0.028	9%	0.088	C	C	.	.	H	α-helix	trans	-58.7	-44.1	177.8	-73.3	0	0	0	0	111.9	V263 Q264 L270 N271 F283 P286	V263-S267 PolarHBondContact O-N 3.23Å; V263-S267 PolarHBondContact O-OG 2.89Å; Q264-S267 PolarHBondContact O-N 2.82Å; S267-L270 PolarHBondContact O-N 3.44Å; S267-N271 VanDerWaalsContact O-CB 3.25Å; S267-N271 WeakPolarHBondContact O-CB 3.45Å; S267-N271 PolarHBondContact O-N 3.22Å; S267-F283 PolarHBondContact OG-O 2.83Å; S267-P286 WeakPolarHBondContact OG-CB 3.37Å
268	T	88.8	Confident	87.5	Confident	5 Å²	5	18.6 Å²	18.6	3%	0.031	11%	0.105	C	C	.	.	H	α-helix	trans	-66.2	-40.1	178.7	-60	0	0	0	0	111.9	V32 L35 Q264 L265 C266 N271 V272	V32-T268 HydrophobicContact CG2-CG2 3.94Å; L35-T268 HydrophobicContact CD2-CG2 3.67Å; Q264-T268 PolarHBondContact O-N 3.21Å; Q264-T268 PolarHBondContact O-OG1 3.23Å; Q264-T268 VanDerWaalsContact O-OG1 3.07Å; L265-T268 PolarHBondContact O-N 3.36Å; C266-T268 VanDerWaalsContact C-N 3.33Å; C266-T268 PolarHBondContact O-N 3.38Å; T268-N271 PolarHBondContact O-N 3.1Å; T268-V272 HydrophobicContact CG2-CG2 3.94Å; T268-V272 VanDerWaalsContact O-CB 3.29Å; T268-V272 WeakPolarHBondContact O-CB 3.47Å; T268-V272 WeakPolarHBondContact O-CG2 3.47Å; T268-V272 PolarHBondContact O-N 3.34Å
269	I	89.6	Confident	86.8	Confident	2 Å²	2	18.8 Å²	18.8	1%	0.01	11%	0.106	C	C	.	.	H	α-helix	trans	-64.4	-45.4	176.3	-71.2	176.2	0	0	0	110.7	V95 M134 I159 L163 L265 C266 N271 V272 A273 F274	V95-I269 HydrophobicContact CG1-CB 4.37Å; V95-I269 HydrophobicContact CG1-CG2 3.88Å; M134-I269 HydrophobicContact CE-CD1 3.51Å; M134-I269 HydrophobicContact CE-CG2 4.2Å; M134-I269 HydrophobicContact SD-CD1 3.53Å; M134-I269 VanDerWaalsContact SD-CD1 3.53Å; I159-I269 HydrophobicContact CG1-CG2 4.38Å; I159-I269 HydrophobicContact CG2-CG2 4.48Å; L163-I269 HydrophobicContact CD2-CD1 3.84Å; L163-I269 HydrophobicContact CG-CD1 4.16Å; L265-I269 HydrophobicContact CD2-CD1 3.43Å; L265-I269 VanDerWaalsContact CD2-CD1 3.43Å; L265-I269 HydrophobicContact CD2-CG1 4.35Å; L265-I269 HydrophobicContact CG-CD1 4.03Å; L265-I269 WeakPolarHBondContact O-CG1 3.26Å; L265-I269 PolarHBondContact O-N 2.99Å; C266-I269 PolarHBondContact O-N 3.05Å; I269-N271 PolarHBondContact O-N 3.3Å; I269-V272 PolarHBondContact O-N 2.99Å; I269-A273 HydrophobicContact CG2-CB 4.08Å; I269-A273 WeakPolarHBondContact O-CA 3.22Å; I269-A273 WeakPolarHBondContact O-CB 3.38Å; I269-A273 PolarHBondContact O-N 2.77Å; I269-F274 HydrophobicContact CG2-CE2 4.21Å
270	L	89.4	Confident	86	Confident	1 Å²	1	19 Å²	19	1%	0.005	11%	0.108	C	C	.	.	H	α-helix	trans	-60.3	-36.4	176.6	-71.1	175.4	0	0	0	112.2	A92 V95 C266 S267 F274 I279 F283 P286	A92-L270 HydrophobicContact CB-CD1 4.38Å; A92-L270 HydrophobicContact CB-CD2 4.23Å; V95-L270 HydrophobicContact CB-CD2 3.97Å; V95-L270 HydrophobicContact CG1-CD2 3.89Å; V95-L270 HydrophobicContact CG1-CG 4.01Å; V95-L270 HydrophobicContact CG2-CD2 4.1Å; C266-L270 WeakPolarHBondContact O-CG 3.3Å; C266-L270 PolarHBondContact O-N 2.99Å; S267-L270 PolarHBondContact O-N 3.44Å; L270-F274 HydrophobicContact CD2-CD2 4.32Å; L270-F274 HydrophobicContact CD2-CE2 4.26Å; L270-I279 HydrophobicContact CB-CG2 4.23Å; L270-I279 HydrophobicContact CD2-CD1 3.94Å; L270-F283 HydrophobicContact CB-CB 4.18Å; L270-P286 HydrophobicContact CD1-CG 3.87Å
271	N	85.4	Confident	85.2	Confident	26 Å²	26	19.1 Å²	19.1	14%	0.139	11%	0.109	C	C	.	.	H	α-helix	trans	-81.3	-36.6	-178.4	179.3	-105.1	0	0	0	114	S28 L31 S267 T268 I269	S28-N271 WeakPolarHBondContact CA-OD1 3.3Å; S28-N271 WeakPolarHBondContact CB-OD1 3.26Å; S28-N271 PolarHBondContact OG-OD1 3.45Å; S28-N271 VanDerWaalsContact OG-OD1 3.08Å; L31-N271 HydrophobicContact CD1-CB 3.89Å; S267-N271 VanDerWaalsContact O-CB 3.25Å; S267-N271 WeakPolarHBondContact O-CB 3.45Å; S267-N271 PolarHBondContact O-N 3.22Å; T268-N271 PolarHBondContact O-N 3.1Å; I269-N271 PolarHBondContact O-N 3.3Å
272	V	84.9	Confident	84.6	Confident	61 Å²	61	19.1 Å²	19.1	37%	0.37	11%	0.109	S	C	.	.	H	α-helix	trans	-98.6	-39.5	-172.7	176.4	0	0	0	0	112.5	V32 T268 I269	V32-V272 HydrophobicContact CG2-CG2 3.95Å; T268-V272 HydrophobicContact CG2-CG2 3.94Å; T268-V272 VanDerWaalsContact O-CB 3.29Å; T268-V272 WeakPolarHBondContact O-CB 3.47Å; T268-V272 WeakPolarHBondContact O-CG2 3.47Å; T268-V272 PolarHBondContact O-N 3.34Å; I269-V272 PolarHBondContact O-N 2.99Å
273	A	85.8	Confident	84	Confident	0 Å²	0	19.4 Å²	19.4	0%	0	11%	0.11	C	C	.	.	T	Hydrogen-bonded Turn	trans	-78.2	-32.9	-174.6	0	0	0	0	0	111.9	P155 R158 I159 I269	P155-A273 WeakPolarHBondContact CG-O 3.48Å; R158-A273 HydrophobicContact CB-CB 4.13Å; R158-A273 VanDerWaalsContact CD-O 3.23Å; R158-A273 WeakPolarHBondContact CD-O 3.02Å; I159-A273 HydrophobicContact CG1-CB 3.8Å; I269-A273 HydrophobicContact CG2-CB 4.08Å; I269-A273 WeakPolarHBondContact O-CA 3.22Å; I269-A273 WeakPolarHBondContact O-CB 3.38Å; I269-A273 PolarHBondContact O-N 2.77Å
274	F	84.6	Confident	83.5	Confident	4 Å²	4	19.5 Å²	19.5	2%	0.018	11%	0.11	C	C	.	.	S	Bend	trans	-105.2	148.9	-175.5	-62.3	-91	0	0	0	112.2	L91 V95 V154 P155 I159 I269 L270 I279	L91-F274 HydrophobicContact CD1-CZ 4.42Å; L91-F274 HydrophobicContact CD2-CD1 4.31Å; L91-F274 HydrophobicContact CD2-CE1 3.65Å; L91-F274 HydrophobicContact CD2-CZ 4.22Å; L91-F274 HydrophobicContact CG-CE1 4.28Å; L91-F274 HydrophobicContact CG-CZ 4.37Å; V95-F274 HydrophobicContact CG2-CE2 4.04Å; V95-F274 HydrophobicContact CG2-CZ 4.05Å; V154-F274 HydrophobicContact CG1-CE1 4.48Å; P155-F274 HydrophobicContact CG-CD1 3.84Å; P155-F274 HydrophobicContact CG-CE1 3.96Å; P155-F274 HydrophobicContact CG-CG 4.28Å; I159-F274 HydrophobicContact CD1-CE2 4.23Å; I159-F274 HydrophobicContact CD1-CZ 3.85Å; I159-F274 HydrophobicContact CG1-CE2 4.45Å; I159-F274 HydrophobicContact CG1-CZ 4.49Å; I269-F274 HydrophobicContact CG2-CE2 4.21Å; L270-F274 HydrophobicContact CD2-CD2 4.32Å; L270-F274 HydrophobicContact CD2-CE2 4.26Å; F274-I279 HydrophobicContact CB-CD1 4.06Å; F274-I279 HydrophobicContact CB-CG1 3.31Å; F274-I279 HydrophobicContact CD1-CD1 4.32Å; F274-I279 HydrophobicContact CD1-CG1 4.47Å; F274-I279 HydrophobicContact CD2-CD1 4.38Å; F274-I279 HydrophobicContact CD2-CG1 4.28Å; F274-I279 HydrophobicContact CG-CD1 4Å; F274-I279 HydrophobicContact CG-CG1 3.8Å
275	P	79.8	Confident	83.5	Confident	49 Å²	49	18.9 Å²	18.9	32%	0.318	11%	0.107	S	C	.	.			trans	-60.7	135.5	173.2	-19.6	31.6	0	0	0	111.4	E277 V278 I279	P275-E277 VanDerWaalsContact CB-OE2 3.28Å; P275-E277 WeakPolarHBondContact CB-OE2 3.25Å; P275-E277 PolarHBondContact O-N 2.66Å; P275-E277 VanDerWaalsContact O-N 3.14Å; P275-V278 HydrophobicContact CB-CB 4.49Å; P275-V278 HydrophobicContact CB-CG2 4.07Å; P275-V278 HydrophobicContact CG-CG2 4.13Å; P275-V278 PolarHBondContact O-N 3.45Å; P275-I279 PolarHBondContact O-N 3.2Å
276	P	74.3	Confident	83.6	Confident	44 Å²	44	18.9 Å²	18.9	29%	0.286	11%	0.107	S	C	.	.	H	α-helix	trans	-56.3	-28.8	178	-26.8	35.6	0	0	0	113.8	F18 V278 G280	F18-P276 HydrophobicContact CD1-CB 4.03Å; F18-P276 HydrophobicContact CE1-CB 4.09Å; P276-V278 VanDerWaalsContact C-N 3.27Å; P276-V278 PolarHBondContact O-N 2.86Å; P276-G280 WeakPolarHBondContact O-CA 3.45Å; P276-G280 PolarHBondContact O-N 3.46Å
277	E	71.4	Confident	83.3	Confident	104 Å²	104	21.6 Å²	21.6	49%	0.486	12%	0.121	S	C	.	.	H	α-helix	trans	-68.7	-27	177.9	-55.1	79.6	-173.8	0	0	112.4	P275	P275-E277 VanDerWaalsContact CB-OE2 3.28Å; P275-E277 WeakPolarHBondContact CB-OE2 3.25Å; P275-E277 PolarHBondContact O-N 2.66Å; P275-E277 VanDerWaalsContact O-N 3.14Å
278	V	76.4	Confident	83.3	Confident	62 Å²	62	21.9 Å²	21.9	38%	0.376	12%	0.122	S	C	.	.	H	α-helix	trans	-87.4	-51.2	-179.3	177.3	0	0	0	0	110.5	I88 P275 P276	I88-V278 HydrophobicContact CD1-CG1 3.67Å; I88-V278 HydrophobicContact CG1-CG1 4.44Å; I88-V278 HydrophobicContact CG2-CG1 4.37Å; I88-V278 WeakPolarHBondContact CG2-O 3.19Å; P275-V278 HydrophobicContact CB-CB 4.49Å; P275-V278 HydrophobicContact CB-CG2 4.07Å; P275-V278 HydrophobicContact CG-CG2 4.13Å; P275-V278 PolarHBondContact O-N 3.45Å; P276-V278 VanDerWaalsContact C-N 3.27Å; P276-V278 PolarHBondContact O-N 2.86Å
279	I	81	Confident	83.6	Confident	5 Å²	5	21.6 Å²	21.6	3%	0.026	12%	0.121	C	C	.	.	H	α-helix	trans	-77.1	-32.8	-177.2	-69.1	-56.8	0	0	0	112	I88 L270 F274 P275 L282 F283	I88-I279 HydrophobicContact CG2-CD1 4.27Å; L270-I279 HydrophobicContact CB-CG2 4.23Å; L270-I279 HydrophobicContact CD2-CD1 3.94Å; F274-I279 HydrophobicContact CB-CD1 4.06Å; F274-I279 HydrophobicContact CB-CG1 3.31Å; F274-I279 HydrophobicContact CD1-CD1 4.32Å; F274-I279 HydrophobicContact CD1-CG1 4.47Å; F274-I279 HydrophobicContact CD2-CD1 4.38Å; F274-I279 HydrophobicContact CD2-CG1 4.28Å; F274-I279 HydrophobicContact CG-CD1 4Å; F274-I279 HydrophobicContact CG-CG1 3.8Å; P275-I279 PolarHBondContact O-N 3.2Å; I279-L282 HydrophobicContact CG2-CB 4.15Å; I279-L282 VanDerWaalsContact O-CB 3.27Å; I279-L282 WeakPolarHBondContact O-CB 3.22Å; I279-L282 PolarHBondContact O-N 3.46Å; I279-F283 HydrophobicContact CG2-CB 4.07Å
280	G	78.6	Confident	83.8	Confident	3 Å²	3	24.9 Å²	24.9	3%	0.031	14%	0.137	C	C	.	.	G	3₁₀ helix	trans	50	-128.1	-178.8	0	0	0	0	0	111.4	P276 L282 F283	P276-G280 WeakPolarHBondContact O-CA 3.45Å; P276-G280 PolarHBondContact O-N 3.46Å; G280-L282 VanDerWaalsContact C-N 3.29Å; G280-L282 PolarHBondContact O-N 2.97Å; G280-F283 VanDerWaalsContact O-CD1 3.26Å; G280-F283 WeakPolarHBondContact O-CD1 3.27Å
281	P	77.7	Confident	83.9	Confident	3 Å²	3	30.1 Å²	30.1	2%	0.019	16%	0.164	C	C	.	.	G	3₁₀ helix	trans	-79.2	-3.6	-179.9	33.8	-37.9	0	0	0	113.9	F12 V210 F216 F283 F284	F12-P281 VanDerWaalsContact CE2-CD 3.41Å; F12-P281 HydrophobicContact CE2-CG 3.79Å; F12-P281 HydrophobicContact CZ-CG 4.19Å; V210-P281 HydrophobicContact CG1-CB 4.06Å; F216-P281 HydrophobicContact CB-CG 3.85Å; F216-P281 HydrophobicContact CD1-CG 3.64Å; F216-P281 HydrophobicContact CG-CG 4.04Å; P281-F283 PolarHBondContact O-N 3.47Å; P281-F283 VanDerWaalsContact O-N 3.14Å; P281-F284 HydrophobicContact CB-CD2 4.3Å; P281-F284 WeakPolarHBondContact O-CB 3.46Å; P281-F284 VanDerWaalsContact O-CD2 3.22Å; P281-F284 WeakPolarHBondContact O-CD2 3.46Å; P281-F284 PolarHBondContact O-N 3.38Å
282	L	83.6	Confident	84.4	Confident	4 Å²	4	31.5 Å²	31.5	2%	0.021	17%	0.169	C	C	.	.	G	3₁₀ helix	trans	-68.3	-12.7	-176.5	-66.6	167	0	0	0	113.3	I88 E89 A92 F216 L222 I279 G280 F284 F285	I88-L282 HydrophobicContact CB-CD1 4.18Å; I88-L282 HydrophobicContact CG2-CD1 3.48Å; I88-L282 VanDerWaalsContact CG2-CD1 3.48Å; E89-L282 HydrophobicContact CG-CD1 4.01Å; E89-L282 HydrophobicContact CG-CD2 4.05Å; A92-L282 HydrophobicContact CB-CB 3.94Å; A92-L282 HydrophobicContact CB-CD1 4.33Å; F216-L282 HydrophobicContact CE1-CD2 4.29Å; F216-L282 HydrophobicContact CE1-CG 4.44Å; L222-L282 HydrophobicContact CD1-CD2 3.68Å; L222-L282 HydrophobicContact CD2-CD2 4.46Å; I279-L282 HydrophobicContact CG2-CB 4.15Å; I279-L282 VanDerWaalsContact O-CB 3.27Å; I279-L282 WeakPolarHBondContact O-CB 3.22Å; I279-L282 PolarHBondContact O-N 3.46Å; G280-L282 VanDerWaalsContact C-N 3.29Å; G280-L282 PolarHBondContact O-N 2.97Å; L282-F284 PolarHBondContact O-N 3.29Å; L282-F284 VanDerWaalsContact O-N 3.1Å; L282-F285 VanDerWaalsContact O-CB 3.24Å; L282-F285 WeakPolarHBondContact O-CB 3.38Å; L282-F285 PolarHBondContact O-N 3.39Å
283	F	81.1	Confident	84.9	Confident	12 Å²	12	28.7 Å²	28.7	5%	0.053	15%	0.152	C	C	.	.	G	3₁₀ helix	trans	-63	-12.2	169	83.4	-87.1	0	0	0	113.5	F18 L27 V210 S267 L270 I279 G280 P281 P286	F18-F283 HydrophobicContact CZ-CE1 4.44Å; L27-F283 HydrophobicContact CD1-CE2 4.27Å; L27-F283 HydrophobicContact CD1-CZ 4.12Å; L27-F283 HydrophobicContact CD2-CE2 4.13Å; L27-F283 HydrophobicContact CD2-CZ 4.49Å; V210-F283 HydrophobicContact CG2-CE1 4.11Å; V210-F283 HydrophobicContact CG2-CZ 4.31Å; S267-F283 PolarHBondContact OG-O 2.83Å; L270-F283 HydrophobicContact CB-CB 4.18Å; I279-F283 HydrophobicContact CG2-CB 4.07Å; G280-F283 VanDerWaalsContact O-CD1 3.26Å; G280-F283 WeakPolarHBondContact O-CD1 3.27Å; P281-F283 PolarHBondContact O-N 3.47Å; P281-F283 VanDerWaalsContact O-N 3.14Å; F283-P286 VanDerWaalsContact O-CD 3.29Å; F283-P286 WeakPolarHBondContact O-CD 3.46Å
284	F	80.9	Confident	85.3	Confident	6 Å²	6	32.2 Å²	32.2	3%	0.026	17%	0.17	C	C	.	.	G	3₁₀ helix	trans	-84.5	-15.7	170.8	-67.7	-58.7	0	0	0	114.6	S206 V210 I214 A217 P281 L282 P286 L287 L288	S206-F284 WeakPolarHBondContact OG-CE1 3.38Å; S206-F284 WeakPolarHBondContact OG-CZ 3.14Å; V210-F284 HydrophobicContact CB-CE2 3.76Å; V210-F284 HydrophobicContact CB-CZ 4.26Å; V210-F284 HydrophobicContact CG1-CE2 3.82Å; V210-F284 HydrophobicContact CG2-CE2 3.61Å; V210-F284 HydrophobicContact CG2-CZ 4.01Å; I214-F284 HydrophobicContact CD1-CD1 4.3Å; I214-F284 HydrophobicContact CD1-CD2 4.01Å; I214-F284 HydrophobicContact CD1-CE1 4.35Å; I214-F284 HydrophobicContact CD1-CE2 4.05Å; I214-F284 HydrophobicContact CD1-CG 4.13Å; I214-F284 HydrophobicContact CD1-CZ 4.23Å; I214-F284 HydrophobicContact CG1-CD2 4.08Å; I214-F284 HydrophobicContact CG1-CE2 4.4Å; I214-F284 HydrophobicContact CG1-CG 4.43Å; A217-F284 HydrophobicContact CB-CB 4.12Å; P281-F284 HydrophobicContact CB-CD2 4.3Å; P281-F284 WeakPolarHBondContact O-CB 3.46Å; P281-F284 VanDerWaalsContact O-CD2 3.22Å; P281-F284 WeakPolarHBondContact O-CD2 3.46Å; P281-F284 PolarHBondContact O-N 3.38Å; L282-F284 PolarHBondContact O-N 3.29Å; L282-F284 VanDerWaalsContact O-N 3.1Å; F284-P286 VanDerWaalsContact C-N 3.26Å; F284-L287 HydrophobicContact CD1-CD1 3.7Å; F284-L287 HydrophobicContact CD1-CG 4.49Å; F284-L287 HydrophobicContact CE1-CD1 4.27Å; F284-L287 WeakPolarHBondContact O-CA 2.97Å; F284-L287 WeakPolarHBondContact O-CB 3.46Å; F284-L287 PolarHBondContact O-N 3.21Å; F284-L288 PolarHBondContact O-N 3.19Å
285	F	89.3	Confident	85.9	Confident	1 Å²	1	34 Å²	34	0%	0.004	19%	0.189	C	C	.	.	H	α-helix	trans	-51.3	-42.3	176.8	174.4	-92.5	0	0	0	112.7	I93 C96 L222 T225 M229 L282 L287 L288 Y289	I93-F285 HydrophobicContact CB-CE1 4.03Å; I93-F285 HydrophobicContact CB-CZ 3.95Å; I93-F285 HydrophobicContact CG2-CD1 4.13Å; I93-F285 HydrophobicContact CG2-CD2 3.95Å; I93-F285 HydrophobicContact CG2-CE1 3.71Å; I93-F285 HydrophobicContact CG2-CE2 3.48Å; I93-F285 VanDerWaalsContact CG2-CE2 3.48Å; I93-F285 HydrophobicContact CG2-CG 4.25Å; I93-F285 HydrophobicContact CG2-CZ 3.35Å; C96-F285 HydrophobicContact CB-CD1 4.17Å; C96-F285 HydrophobicContact CB-CE1 3.83Å; L222-F285 HydrophobicContact CD2-CD2 4.06Å; L222-F285 HydrophobicContact CD2-CE2 4.32Å; T225-F285 HydrophobicContact CG2-CE2 4.42Å; T225-F285 HydrophobicContact CG2-CZ 4.3Å; M229-F285 HydrophobicContact SD-CE1 4.39Å; M229-F285 HydrophobicContact SD-CZ 4.04Å; L282-F285 VanDerWaalsContact O-CB 3.24Å; L282-F285 WeakPolarHBondContact O-CB 3.38Å; L282-F285 PolarHBondContact O-N 3.39Å; F285-L287 VanDerWaalsContact C-N 3.25Å; F285-L287 PolarHBondContact O-N 2.9Å; F285-L288 WeakPolarHBondContact O-CB 3.25Å; F285-L288 PolarHBondContact O-N 3.42Å; F285-L288 VanDerWaalsContact O-N 3.11Å; F285-Y289 HydrophobicContact CE1-CD2 4.4Å; F285-Y289 PolarHBondContact O-N 3.16Å
286	P	91.4	Very high	86.7	Confident	0 Å²	0	32.7 Å²	32.7	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-64.2	-26.8	176.6	-22.8	36.8	0	0	0	113.6	V263 C266 S267 L270 F283 F284 Y289 M290	V263-P286 HydrophobicContact CB-CB 4.4Å; V263-P286 HydrophobicContact CG1-CB 3.68Å; V263-P286 WeakPolarHBondContact CG1-O 3.37Å; V263-P286 WeakPolarHBondContact CG2-O 3.24Å; C266-P286 HydrophobicContact CB-CB 4.13Å; C266-P286 HydrophobicContact CB-CG 3.93Å; C266-P286 WeakPolarHBondContact SG-CG 3.46Å; S267-P286 WeakPolarHBondContact OG-CB 3.37Å; L270-P286 HydrophobicContact CD1-CG 3.87Å; F283-P286 VanDerWaalsContact O-CD 3.29Å; F283-P286 WeakPolarHBondContact O-CD 3.46Å; F284-P286 VanDerWaalsContact C-N 3.26Å; P286-Y289 WeakPolarHBondContact O-CB 3.35Å; P286-Y289 PolarHBondContact O-N 2.98Å; P286-M290 PolarHBondContact O-N 2.84Å
287	L	86.8	Confident	87.7	Confident	57 Å²	57	30.6 Å²	30.6	30%	0.298	17%	0.166	S	C	.	.	H	α-helix	trans	-70.3	-39.1	172.9	-59.8	-173.4	0	0	0	111.5	V263 F284 F285 M290 I291	V263-L287 HydrophobicContact CG1-CD2 4.43Å; F284-L287 HydrophobicContact CD1-CD1 3.7Å; F284-L287 HydrophobicContact CD1-CG 4.49Å; F284-L287 HydrophobicContact CE1-CD1 4.27Å; F284-L287 WeakPolarHBondContact O-CA 2.97Å; F284-L287 WeakPolarHBondContact O-CB 3.46Å; F284-L287 PolarHBondContact O-N 3.21Å; F285-L287 VanDerWaalsContact C-N 3.25Å; F285-L287 PolarHBondContact O-N 2.9Å; L287-M290 VanDerWaalsContact O-CB 3.26Å; L287-M290 WeakPolarHBondContact O-CB 3.22Å; L287-M290 PolarHBondContact O-N 2.94Å; L287-M290 VanDerWaalsContact O-N 3.14Å; L287-I291 WeakPolarHBondContact O-CG1 3.45Å; L287-I291 PolarHBondContact O-N 3.32Å; L287-I291 VanDerWaalsContact O-N 3.12Å
288	L	89.4	Confident	88.9	Confident	10 Å²	10	29.9 Å²	29.9	5%	0.052	16%	0.164	C	C	.	.	H	α-helix	trans	-60.5	-47.6	171	-81.7	177.2	0	0	0	111.3	A217 M218 F284 F285 M290 I291 F292	A217-L288 WeakPolarHBondContact O-CD1 3.38Å; M218-L288 HydrophobicContact CE-CD1 3.7Å; M218-L288 HydrophobicContact CE-CD2 3.37Å; M218-L288 HydrophobicContact CE-CG 3.54Å; M218-L288 HydrophobicContact SD-CD1 4.08Å; M218-L288 HydrophobicContact SD-CD2 3.62Å; M218-L288 HydrophobicContact SD-CG 4.24Å; F284-L288 PolarHBondContact O-N 3.19Å; F285-L288 WeakPolarHBondContact O-CB 3.25Å; F285-L288 PolarHBondContact O-N 3.42Å; F285-L288 VanDerWaalsContact O-N 3.11Å; L288-M290 PolarHBondContact O-N 3.16Å; L288-I291 PolarHBondContact O-N 3.37Å; L288-I291 VanDerWaalsContact O-N 3.1Å; L288-F292 WeakPolarHBondContact O-CD2 3.3Å; L288-F292 PolarHBondContact O-N 3.26Å; L288-F292 VanDerWaalsContact O-N 3.15Å
289	Y	94.1	Very high	89.9	Confident	0 Å²	0	31.5 Å²	31.5	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-53.8	-41.3	172.2	-169.6	-73.8	0	0	0	111.2	M72 M229 P230 G259 Q261 V263 F285 P286 I291 F292 Q293	M72-Y289 WeakPolarHBondContact CE-OH 3.39Å; M229-Y289 HydrophobicContact CB-CD2 4.26Å; M229-Y289 HydrophobicContact CB-CE2 3.6Å; M229-Y289 HydrophobicContact CE-CE2 4.18Å; M229-Y289 HydrophobicContact SD-CE2 4.44Å; P230-Y289 WeakPolarHBondContact CA-OH 3.49Å; P230-Y289 HydrophobicContact CB-CE1 4.11Å; P230-Y289 HydrophobicContact CB-CE2 4.42Å; P230-Y289 HydrophobicContact CG-CE1 4.44Å; P230-Y289 HydrophobicContact CG-CE2 4.28Å; G259-Y289 PolarHBondContact O-OH 3.44Å; Q261-Y289 HydrophobicContact CB-CD1 4.39Å; Q261-Y289 HydrophobicContact CB-CE1 3.75Å; Q261-Y289 HydrophobicContact CG-CE1 3.93Å; Q261-Y289 HydrophobicContact CG-CE2 4.29Å; Q261-Y289 WeakPolarHBondContact CG-OH 3.46Å; V263-Y289 HydrophobicContact CG2-CD1 4.04Å; F285-Y289 HydrophobicContact CE1-CD2 4.4Å; F285-Y289 PolarHBondContact O-N 3.16Å; P286-Y289 WeakPolarHBondContact O-CB 3.35Å; P286-Y289 PolarHBondContact O-N 2.98Å; Y289-I291 VanDerWaalsContact C-N 3.34Å; Y289-I291 PolarHBondContact O-N 2.9Å; Y289-F292 PolarHBondContact O-N 2.67Å; Y289-Q293 HydrophobicContact CD1-CB 4.1Å; Y289-Q293 HydrophobicContact CD1-CG 4.18Å; Y289-Q293 HydrophobicContact CE1-CB 3.84Å; Y289-Q293 HydrophobicContact CE1-CG 4.23Å; Y289-Q293 VanDerWaalsContact CE1-OE1 3.22Å; Y289-Q293 WeakPolarHBondContact O-CB 3.23Å; Y289-Q293 WeakPolarHBondContact O-CG 3.47Å; Y289-Q293 PolarHBondContact O-N 2.82Å
290	M	92.8	Very high	90.6	Very high	70 Å²	70	33.5 Å²	33.5	35%	0.345	18%	0.181	S	C	.	.	H	α-helix	trans	-58.9	-43.7	177.7	-167.4	-175.5	-71	0	0	112.5	V263 P286 L287 L288 Q293 L294	V263-M290 HydrophobicContact CB-CE 3.89Å; V263-M290 HydrophobicContact CG1-CB 4.19Å; V263-M290 HydrophobicContact CG1-CE 3.45Å; V263-M290 VanDerWaalsContact CG1-CE 3.45Å; V263-M290 HydrophobicContact CG2-CB 4.06Å; P286-M290 PolarHBondContact O-N 2.84Å; L287-M290 VanDerWaalsContact O-CB 3.26Å; L287-M290 WeakPolarHBondContact O-CB 3.22Å; L287-M290 PolarHBondContact O-N 2.94Å; L287-M290 VanDerWaalsContact O-N 3.14Å; L288-M290 PolarHBondContact O-N 3.16Å; M290-Q293 WeakPolarHBondContact O-CG 3.49Å; M290-L294 VanDerWaalsContact O-CB 3.23Å; M290-L294 WeakPolarHBondContact O-CB 3.46Å; M290-L294 PolarHBondContact O-N 3.2Å; M290-L294 VanDerWaalsContact O-N 3.07Å
291	I	92.3	Very high	91.4	Very high	112 Å²	112	34.4 Å²	34.4	57%	0.574	19%	0.185	S	C	*	.	H	α-helix	trans	-63.6	-48.2	-179.8	-65.1	165.9	0	0	0	109.8	L287 L288 Y289 L294 G295	L287-I291 WeakPolarHBondContact O-CG1 3.45Å; L287-I291 PolarHBondContact O-N 3.32Å; L287-I291 VanDerWaalsContact O-N 3.12Å; L288-I291 PolarHBondContact O-N 3.37Å; L288-I291 VanDerWaalsContact O-N 3.1Å; Y289-I291 VanDerWaalsContact C-N 3.34Å; Y289-I291 PolarHBondContact O-N 2.9Å; I291-L294 PolarHBondContact O-N 3.1Å; I291-G295 PolarHBondContact O-N 2.96Å
292	F	95.3	Very high	92.3	Very high	55 Å²	55	38.4 Å²	38.4	24%	0.241	21%	0.209	C	C	.	.	H	α-helix	trans	-69.3	-46.6	-178.8	-75	-67.2	0	0	0	113.1	I223 S226 S227 P230 L288 Y289 L294 G295 E296	I223-F292 HydrophobicContact CG2-CE2 3.95Å; I223-F292 HydrophobicContact CG2-CZ 3.68Å; S226-F292 WeakPolarHBondContact O-CB 3.45Å; S226-F292 WeakPolarHBondContact OG-CD2 3.12Å; S226-F292 WeakPolarHBondContact OG-CE2 3.5Å; S227-F292 VanDerWaalsContact CB-CD1 3.43Å; P230-F292 HydrophobicContact CG-CB 4.16Å; L288-F292 WeakPolarHBondContact O-CD2 3.3Å; L288-F292 PolarHBondContact O-N 3.26Å; L288-F292 VanDerWaalsContact O-N 3.15Å; Y289-F292 PolarHBondContact O-N 2.67Å; F292-L294 PolarHBondContact O-N 3.14Å; F292-G295 PolarHBondContact O-N 3.09Å; F292-E296 VanDerWaalsContact O-CB 3.32Å; F292-E296 WeakPolarHBondContact O-CB 3.26Å; F292-E296 WeakPolarHBondContact O-CG 3.28Å; F292-E296 PolarHBondContact O-N 3.28Å
293	Q	96.1	Very high	92.8	Very high	2 Å²	2	43.4 Å²	43.4	1%	0.009	23%	0.233	C	C	.	.	H	α-helix	trans	-60.4	-33.3	176.7	77.8	178.5	-18	0	0	111.7	L104 F108 P230 Q261 Y289 M290 G297	L104-Q293 HydrophobicContact CD1-CG 4.45Å; F108-Q293 WeakPolarHBondContact CE2-O 3.06Å; P230-Q293 HydrophobicContact CB-CB 3.73Å; P230-Q293 HydrophobicContact CG-CB 4.26Å; Q261-Q293 VanDerWaalsContact N-OE1 3.14Å; Y289-Q293 HydrophobicContact CD1-CB 4.1Å; Y289-Q293 HydrophobicContact CD1-CG 4.18Å; Y289-Q293 HydrophobicContact CE1-CB 3.84Å; Y289-Q293 HydrophobicContact CE1-CG 4.23Å; Y289-Q293 VanDerWaalsContact CE1-OE1 3.22Å; Y289-Q293 WeakPolarHBondContact O-CB 3.23Å; Y289-Q293 WeakPolarHBondContact O-CG 3.47Å; Y289-Q293 PolarHBondContact O-N 2.82Å; M290-Q293 WeakPolarHBondContact O-CG 3.49Å; Q293-G297 PolarHBondContact O-N 3.44Å
294	L	95.2	Very high	93.4	Very high	74 Å²	74	44.2 Å²	44.2	39%	0.387	24%	0.237	S	C	.	.	H	α-helix	trans	-69.4	-50.1	176.2	-171.6	84.7	0	0	0	110.5	F108 M290 I291 F292 G297 L298	F108-L294 HydrophobicContact CZ-CD1 4.02Å; M290-L294 VanDerWaalsContact O-CB 3.23Å; M290-L294 WeakPolarHBondContact O-CB 3.46Å; M290-L294 PolarHBondContact O-N 3.2Å; M290-L294 VanDerWaalsContact O-N 3.07Å; I291-L294 PolarHBondContact O-N 3.1Å; F292-L294 PolarHBondContact O-N 3.14Å; L294-G297 PolarHBondContact O-N 2.83Å; L294-L298 HydrophobicContact CG-CD1 4.18Å; L294-L298 WeakPolarHBondContact O-CB 3.29Å; L294-L298 VanDerWaalsContact O-CG 3.22Å; L294-L298 WeakPolarHBondContact O-CG 2.9Å; L294-L298 PolarHBondContact O-N 2.84Å
295	G	95.9	Very high	93.9	Very high	41 Å²	41	49.4 Å²	49.4	42%	0.423	26%	0.256	S	S	.	.	H	α-helix	trans	-60.8	-48.5	179.9	0	0	0	0	0	112.5	I291 F292 L298 L299	I291-G295 PolarHBondContact O-N 2.96Å; F292-G295 PolarHBondContact O-N 3.09Å; G295-L298 PolarHBondContact O-N 3.08Å; G295-L299 WeakPolarHBondContact O-CB 3.13Å; G295-L299 PolarHBondContact O-N 3.36Å
296	E	97.1	Very high	94.1	Very high	22 Å²	22	52.1 Å²	52.1	10%	0.103	28%	0.275	C	S	.	.	H	α-helix	trans	-68	-41.1	179.1	-68.5	170.1	-168.4	0	0	111.9	S227 P230 F231 F234 F292 L298 L299 L300	S227-E296 PolarHBondContact OG-OE1 3.37Å; P230-E296 WeakPolarHBondContact CG-OE2 3.48Å; F231-E296 VanDerWaalsContact CA-OE2 3.23Å; F231-E296 WeakPolarHBondContact CA-OE2 2.93Å; F231-E296 WeakPolarHBondContact CB-OE2 3.5Å; F231-E296 PolarHBondContact N-OE2 2.92Å; F234-E296 HydrophobicContact CD2-CB 4.32Å; F234-E296 HydrophobicContact CE2-CB 3.99Å; F292-E296 VanDerWaalsContact O-CB 3.32Å; F292-E296 WeakPolarHBondContact O-CB 3.26Å; F292-E296 WeakPolarHBondContact O-CG 3.28Å; F292-E296 PolarHBondContact O-N 3.28Å; E296-L298 PolarHBondContact O-N 2.9Å; E296-L299 WeakPolarHBondContact O-CB 3.3Å; E296-L299 PolarHBondContact O-N 3.38Å; E296-L300 WeakPolarHBondContact O-CG 3.47Å; E296-L300 PolarHBondContact O-N 3.49Å
297	G	96	Very high	94.1	Very high	0 Å²	0	58.6 Å²	58.6	0%	0	30%	0.3	C	S	.	.	H	α-helix	trans	-60.7	-44.7	174.2	0	0	0	0	0	112.3	Q293 L294 L300 I301	Q293-G297 PolarHBondContact O-N 3.44Å; L294-G297 PolarHBondContact O-N 2.83Å; G297-L300 PolarHBondContact O-N 3.35Å; G297-I301 WeakPolarHBondContact O-CD1 3.37Å; G297-I301 VanDerWaalsContact O-CG1 3.24Å; G297-I301 WeakPolarHBondContact O-CG1 3.3Å; G297-I301 PolarHBondContact O-N 3.45Å
298	L	96.5	Very high	94.2	Very high	88 Å²	88	58.2 Å²	58.2	46%	0.461	30%	0.297	S	S	.	.	H	α-helix	trans	-62.8	-41.3	173.9	-72.4	174.1	0	0	0	112	F108 L294 G295 E296 I301 V302	F108-L298 HydrophobicContact CE1-CD2 4.42Å; L294-L298 HydrophobicContact CG-CD1 4.18Å; L294-L298 WeakPolarHBondContact O-CB 3.29Å; L294-L298 VanDerWaalsContact O-CG 3.22Å; L294-L298 WeakPolarHBondContact O-CG 2.9Å; L294-L298 PolarHBondContact O-N 2.84Å; G295-L298 PolarHBondContact O-N 3.08Å; E296-L298 PolarHBondContact O-N 2.9Å; L298-I301 HydrophobicContact CD2-CD1 4.45Å; L298-I301 WeakPolarHBondContact O-CB 3.38Å; L298-I301 PolarHBondContact O-N 3.49Å; L298-V302 WeakPolarHBondContact O-CG2 3.34Å; L298-V302 PolarHBondContact O-N 2.91Å
299	L	96.4	Very high	94.1	Very high	96 Å²	96	65.9 Å²	65.9	50%	0.503	33%	0.33	S	S	.	.	H	α-helix	trans	-60.5	-46.5	175.9	-178.6	64.5	0	0	0	111.4	G295 E296 I301 V302 M303	G295-L299 WeakPolarHBondContact O-CB 3.13Å; G295-L299 PolarHBondContact O-N 3.36Å; E296-L299 WeakPolarHBondContact O-CB 3.3Å; E296-L299 PolarHBondContact O-N 3.38Å; L299-I301 VanDerWaalsContact C-N 3.29Å; L299-I301 PolarHBondContact O-N 2.8Å; L299-V302 PolarHBondContact O-N 3.47Å; L299-M303 HydrophobicContact CD1-CE 3.99Å; L299-M303 HydrophobicContact CD2-CE 4.04Å; L299-M303 HydrophobicContact CG-CE 3.87Å; L299-M303 HydrophobicContact CG-SD 4.4Å; L299-M303 WeakPolarHBondContact O-CG 3.41Å; L299-M303 PolarHBondContact O-N 3.31Å
300	L	95.9	Very high	93.6	Very high	48 Å²	48	74 Å²	74	25%	0.251	37%	0.365	S	S	.	.	H	α-helix	trans	-61.3	-38.2	176.1	-71.7	173.6	0	0	0	111.9	F234 M256 E296 G297 M303 F304	F234-L300 HydrophobicContact CB-CD1 3.62Å; F234-L300 HydrophobicContact CD1-CD1 4.26Å; F234-L300 HydrophobicContact CD2-CD1 3.74Å; F234-L300 HydrophobicContact CE2-CD1 4.48Å; F234-L300 HydrophobicContact CG-CD1 3.62Å; M256-L300 HydrophobicContact CE-CB 3.83Å; M256-L300 HydrophobicContact CE-CD1 3.92Å; E296-L300 WeakPolarHBondContact O-CG 3.47Å; E296-L300 PolarHBondContact O-N 3.49Å; G297-L300 PolarHBondContact O-N 3.35Å; L300-M303 PolarHBondContact O-N 2.89Å; L300-F304 VanDerWaalsContact O-CB 3.31Å; L300-F304 WeakPolarHBondContact O-CB 3.33Å; L300-F304 PolarHBondContact O-N 2.93Å
301	I	95.8	Very high	92.8	Very high	22 Å²	22	76.5 Å²	76.5	11%	0.113	37%	0.374	C	S	.	.	H	α-helix	trans	-61.3	-49.2	173.2	-68.3	159.8	0	0	0	111.1	F108 A111 M112 G297 L298 L299 F304 R305	F108-I301 HydrophobicContact CB-CD1 4.4Å; F108-I301 HydrophobicContact CD1-CD1 3.55Å; F108-I301 HydrophobicContact CE1-CD1 4.03Å; F108-I301 HydrophobicContact CG-CD1 4.16Å; A111-I301 HydrophobicContact CB-CD1 3.57Å; A111-I301 HydrophobicContact CB-CG1 3.93Å; A111-I301 HydrophobicContact CB-CG2 4.2Å; M112-I301 HydrophobicContact CG-CG1 3.85Å; M112-I301 WeakPolarHBondContact SD-CA 3.34Å; M112-I301 HydrophobicContact SD-CB 4.16Å; M112-I301 HydrophobicContact SD-CG1 3.7Å; G297-I301 WeakPolarHBondContact O-CD1 3.37Å; G297-I301 VanDerWaalsContact O-CG1 3.24Å; G297-I301 WeakPolarHBondContact O-CG1 3.3Å; G297-I301 PolarHBondContact O-N 3.45Å; L298-I301 HydrophobicContact CD2-CD1 4.45Å; L298-I301 WeakPolarHBondContact O-CB 3.38Å; L298-I301 PolarHBondContact O-N 3.49Å; L299-I301 VanDerWaalsContact C-N 3.29Å; L299-I301 PolarHBondContact O-N 2.8Å; I301-F304 PolarHBondContact O-N 3.36Å; I301-R305 HydrophobicContact CG2-CG 4.31Å; I301-R305 WeakPolarHBondContact O-CB 3.24Å; I301-R305 WeakPolarHBondContact O-CG 3.32Å; I301-R305 PolarHBondContact O-N 3.16Å
302	V	95.5	Very high	91	Very high	86 Å²	86	74.4 Å²	74.4	52%	0.521	37%	0.367	S	S	.	.	H	α-helix	trans	-60.4	-48.2	178.4	172	0	0	0	0	110.5	L298 L299 F304 R305 C306	L298-V302 WeakPolarHBondContact O-CG2 3.34Å; L298-V302 PolarHBondContact O-N 2.91Å; L299-V302 PolarHBondContact O-N 3.47Å; V302-F304 VanDerWaalsContact C-N 3.33Å; V302-F304 PolarHBondContact O-N 3.07Å; V302-R305 PolarHBondContact O-N 3.19Å; V302-C306 WeakPolarHBondContact O-CB 3.37Å; V302-C306 PolarHBondContact O-N 2.93Å; V302-C306 PolarHBondContact O-SG 3.36Å; V302-C306 VanDerWaalsContact O-SG 3.34Å
303	M	94.6	Very high	89	Confident	109 Å²	109	75.4 Å²	75.4	54%	0.537	38%	0.379	S	S	.	.	H	α-helix	trans	-56.8	-45.5	177.3	-73.4	-177.2	175.6	0	0	112	L299 L300 C306 Y307	L299-M303 HydrophobicContact CD1-CE 3.99Å; L299-M303 HydrophobicContact CD2-CE 4.04Å; L299-M303 HydrophobicContact CG-CE 3.87Å; L299-M303 HydrophobicContact CG-SD 4.4Å; L299-M303 WeakPolarHBondContact O-CG 3.41Å; L299-M303 PolarHBondContact O-N 3.31Å; L300-M303 PolarHBondContact O-N 2.89Å; M303-C306 PolarHBondContact O-N 3.32Å; M303-Y307 WeakPolarHBondContact O-CB 3.47Å; M303-Y307 PolarHBondContact O-N 2.82Å
304	F	93.4	Very high	86.7	Confident	29 Å²	29	84 Å²	84	13%	0.127	42%	0.416	C	S	.	.	H	α-helix	trans	-63.4	-44	177.8	174.1	-103.9	0	0	0	112.5	M112 K113 L300 I301 V302 Y307 E308	M112-F304 HydrophobicContact CE-CB 3.47Å; M112-F304 VanDerWaalsContact CE-CB 3.47Å; M112-F304 HydrophobicContact CE-CD1 4.36Å; M112-F304 HydrophobicContact CE-CD2 4.14Å; M112-F304 HydrophobicContact CE-CG 3.74Å; M112-F304 WeakPolarHBondContact O-CE1 3.29Å; M112-F304 WeakPolarHBondContact O-CZ 3.47Å; M112-F304 HydrophobicContact SD-CB 3.54Å; M112-F304 VanDerWaalsContact SD-CB 3.54Å; M112-F304 HydrophobicContact SD-CD1 3.95Å; M112-F304 HydrophobicContact SD-CG 3.84Å; K113-F304 HydrophobicContact CB-CE1 4.34Å; K113-F304 HydrophobicContact CB-CZ 4.48Å; K113-F304 HydrophobicContact CD-CE1 4.22Å; K113-F304 HydrophobicContact CD-CZ 4.46Å; K113-F304 HydrophobicContact CG-CE1 4.21Å; L300-F304 VanDerWaalsContact O-CB 3.31Å; L300-F304 WeakPolarHBondContact O-CB 3.33Å; L300-F304 PolarHBondContact O-N 2.93Å; I301-F304 PolarHBondContact O-N 3.36Å; V302-F304 VanDerWaalsContact C-N 3.33Å; V302-F304 PolarHBondContact O-N 3.07Å; F304-Y307 PolarHBondContact O-N 3.44Å; F304-E308 HydrophobicContact CE1-CG 4.09Å; F304-E308 WeakPolarHBondContact CE1-OE2 3.25Å; F304-E308 HydrophobicContact CE2-CG 4.12Å; F304-E308 VanDerWaalsContact CZ-CD 3.5Å; F304-E308 HydrophobicContact CZ-CG 3.82Å; F304-E308 PolarHBondContact O-N 3.03Å
305	R	92.4	Very high	84.6	Confident	115 Å²	115	85.4 Å²	85.4	43%	0.434	42%	0.424	S	S	.	.	H	α-helix	trans	-66	-39.3	178.3	-66.8	-68.3	-178.8	155.5	1.7	111.9	A111 I301 V302 K309	A111-R305 PolarHBondContact O-NE 3.32Å; A111-R305 PolarHBondContact O-NH2 2.77Å; I301-R305 HydrophobicContact CG2-CG 4.31Å; I301-R305 WeakPolarHBondContact O-CB 3.24Å; I301-R305 WeakPolarHBondContact O-CG 3.32Å; I301-R305 PolarHBondContact O-N 3.16Å; V302-R305 PolarHBondContact O-N 3.19Å; R305-K309 WeakPolarHBondContact O-CB 3.27Å; R305-K309 PolarHBondContact O-N 3.47Å
306	C	92.8	Very high	82.2	Confident	58 Å²	58	90 Å²	90	39%	0.392	43%	0.433	S	S	.	.	H	α-helix	trans	-60.8	-49.9	171.7	-73.2	0	0	0	0	110.8	V302 M303 E308 K309 F310	V302-C306 WeakPolarHBondContact O-CB 3.37Å; V302-C306 PolarHBondContact O-N 2.93Å; V302-C306 PolarHBondContact O-SG 3.36Å; V302-C306 VanDerWaalsContact O-SG 3.34Å; M303-C306 PolarHBondContact O-N 3.32Å; C306-E308 PolarHBondContact O-N 3.4Å; C306-K309 WeakPolarHBondContact O-CB 3.26Å; C306-K309 PolarHBondContact O-N 2.99Å; C306-K309 VanDerWaalsContact O-N 3.09Å; C306-F310 HydrophobicContact CB-CE2 4.49Å; C306-F310 WeakPolarHBondContact O-CD2 3.32Å; C306-F310 PolarHBondContact O-N 3.41Å
307	Y	91	Very high	79.7	Confident	136 Å²	136	92.2 Å²	92.2	53%	0.533	45%	0.448	S	S	.	.	H	α-helix	trans	-57.6	-44.7	177.9	173	-102.9	0	0	0	112.6	M303 F304 K309 F310 K311	M303-Y307 WeakPolarHBondContact O-CB 3.47Å; M303-Y307 PolarHBondContact O-N 2.82Å; F304-Y307 PolarHBondContact O-N 3.44Å; Y307-K309 VanDerWaalsContact C-N 3.33Å; Y307-K309 PolarHBondContact O-N 3.33Å; Y307-F310 PolarHBondContact O-N 3.32Å; Y307-K311 HydrophobicContact CE1-CD 4.08Å; Y307-K311 WeakPolarHBondContact O-CB 3.44Å; Y307-K311 PolarHBondContact O-N 3.48Å
308	E	89.6	Confident	77.1	Confident	49 Å²	49	99.4 Å²	99.4	23%	0.229	48%	0.479	C	S	.	.	H	α-helix	trans	-59.3	-44.7	174.4	-76.9	-163.8	113.6	0	0	111.6	K113 F304 C306 F310 K311 T312	K113-E308 WeakPolarHBondContact CE-OE2 3.21Å; K113-E308 IonicContact NZ-OE1 2.78Å; K113-E308 PolarHBondContact NZ-OE1 2.85Å; K113-E308 IonicContact NZ-OE2 3.34Å; K113-E308 PolarHBondContact NZ-OE2 2.9Å; F304-E308 HydrophobicContact CE1-CG 4.09Å; F304-E308 WeakPolarHBondContact CE1-OE2 3.25Å; F304-E308 HydrophobicContact CE2-CG 4.12Å; F304-E308 VanDerWaalsContact CZ-CD 3.5Å; F304-E308 HydrophobicContact CZ-CG 3.82Å; F304-E308 PolarHBondContact O-N 3.03Å; C306-E308 PolarHBondContact O-N 3.4Å; E308-F310 VanDerWaalsContact C-N 3.31Å; E308-F310 PolarHBondContact O-N 2.98Å; E308-K311 PolarHBondContact O-N 2.82Å; E308-T312 WeakPolarHBondContact O-CB 3.41Å; E308-T312 PolarHBondContact O-N 3.21Å; E308-T312 PolarHBondContact O-OG1 3.36Å
309	K	88	Confident	74.8	Confident	172 Å²	172	102 Å²	102	75%	0.748	49%	0.491	S	S	*	.	H	α-helix	trans	-61.6	-39.2	178.9	-166	-178.8	-179.8	-175.2	0	112	R305 C306 Y307	R305-K309 WeakPolarHBondContact O-CB 3.27Å; R305-K309 PolarHBondContact O-N 3.47Å; C306-K309 WeakPolarHBondContact O-CB 3.26Å; C306-K309 PolarHBondContact O-N 2.99Å; C306-K309 VanDerWaalsContact O-N 3.09Å; Y307-K309 VanDerWaalsContact C-N 3.33Å; Y307-K309 PolarHBondContact O-N 3.33Å
310	F	83.1	Confident	72.5	Confident	169 Å²	169	102.7 Å²	102.7	74%	0.741	49%	0.494	S	S	*	.	H	α-helix	trans	-77.8	-25	178.3	-76	-68.5	0	0	0	114.4	C306 Y307 E308 P313	C306-F310 HydrophobicContact CB-CE2 4.49Å; C306-F310 WeakPolarHBondContact O-CD2 3.32Å; C306-F310 PolarHBondContact O-N 3.41Å; Y307-F310 PolarHBondContact O-N 3.32Å; E308-F310 VanDerWaalsContact C-N 3.31Å; E308-F310 PolarHBondContact O-N 2.98Å; F310-P313 WeakPolarHBondContact O-CD 3.29Å
311	K	75	Confident	70.3	Confident	123 Å²	123	108.1 Å²	108.1	54%	0.535	51%	0.512	S	S	.	.	H	α-helix	trans	-82.7	-29.7	176.3	-167.8	175.3	-179.6	177.5	0	112.9	Y307 E308 P313	Y307-K311 HydrophobicContact CE1-CD 4.08Å; Y307-K311 WeakPolarHBondContact O-CB 3.44Å; Y307-K311 PolarHBondContact O-N 3.48Å; E308-K311 PolarHBondContact O-N 2.82Å; K311-P313 WeakPolarHBondContact O-CD 3.39Å
312	T	56	Low	68.1	Low	68 Å²	68	111 Å²	111	42%	0.417	53%	0.531	S	S	.	.	H	α-helix	trans	-65	-11.2	-179	-51.9	0	0	0	0	117	E308 K316	E308-T312 WeakPolarHBondContact O-CB 3.41Å; E308-T312 PolarHBondContact O-N 3.21Å; E308-T312 PolarHBondContact O-OG1 3.36Å; T312-K316 HydrophobicContact CG2-CD 4.42Å; T312-K316 HydrophobicContact CG2-CG 4.45Å
313	P	53.3	Low	66	Low	76 Å²	76	109.2 Å²	109.2	49%	0.494	53%	0.525	S	S	.	.	H	α-helix	trans	-68.8	-36.8	173.8	-19	32.3	0	0	0	114	F310 K311 T317	F310-P313 WeakPolarHBondContact O-CD 3.29Å; K311-P313 WeakPolarHBondContact O-CD 3.39Å; P313-T317 PolarHBondContact O-OG1 2.97Å
314	K	47.4	Very low	63.9	Low	182 Å²	182	106.4 Å²	106.4	79%	0.791	52%	0.519	S	S	*	.	H	α-helix	trans	-80.9	-30.6	-172.5	-82.5	-174.2	179.8	-177.9	0	114.7	K318	K314-K318 PolarHBondContact O-N 3.26Å; K314-K318 VanDerWaalsContact O-N 3.12Å
315	D	50.4	Low	61.9	Low	104 Å²	104	109.2 Å²	109.2	56%	0.556	54%	0.539	S	S	*	.	H	α-helix	trans	-79	-31.5	179.8	-100.2	-21.8	0	0	0	113	T317 K318 M319	D315-T317 VanDerWaalsContact C-N 3.34Å; D315-K318 PolarHBondContact O-N 3.03Å; D315-M319 WeakPolarHBondContact O-CB 3.36Å; D315-M319 VanDerWaalsContact O-CG 3.29Å; D315-M319 WeakPolarHBondContact O-CG 3.33Å; D315-M319 PolarHBondContact O-N 3.48Å
316	K	45.4	Very low	59.7	Low	138 Å²	138	107.3 Å²	107.3	60%	0.6	54%	0.54	S	S	*	.	H	α-helix	trans	-65	-40.7	171.8	-76.5	-171.2	176.2	-172.7	0	111.2	T312 M319 I320	T312-K316 HydrophobicContact CG2-CD 4.42Å; T312-K316 HydrophobicContact CG2-CG 4.45Å; K316-M319 PolarHBondContact O-N 3.3Å; K316-I320 WeakPolarHBondContact O-CB 3.48Å; K316-I320 VanDerWaalsContact O-CD1 3.32Å; K316-I320 WeakPolarHBondContact O-CD1 3.36Å; K316-I320 WeakPolarHBondContact O-CG1 3.48Å; K316-I320 PolarHBondContact O-N 2.99Å
317	T	45.1	Very low	57.5	Low	69 Å²	69	112.6 Å²	112.6	42%	0.423	56%	0.559	S	S	.	*	H	α-helix	trans	-62.6	-48.1	173.5	-49	0	0	0	0	110.6	P313 D315 M319 I320 Y321	P313-T317 PolarHBondContact O-OG1 2.97Å; D315-T317 VanDerWaalsContact C-N 3.34Å; T317-M319 PolarHBondContact O-N 2.84Å; T317-I320 PolarHBondContact O-N 3.23Å; T317-Y321 HydrophobicContact CG2-CD2 3.66Å; T317-Y321 HydrophobicContact CG2-CE2 3.3Å; T317-Y321 WeakPolarHBondContact O-CB 3.34Å; T317-Y321 WeakPolarHBondContact O-CD2 3.36Å; T317-Y321 PolarHBondContact O-N 2.96Å
318	K	40.6	Very low	55.5	Low	150 Å²	150	114.6 Å²	114.6	65%	0.652	57%	0.573	S	S	*	*	H	α-helix	trans	-60.4	-40.7	176.3	-109.3	-178	176	-173.8	0	113.7	K314 D315 T322	K314-K318 PolarHBondContact O-N 3.26Å; K314-K318 VanDerWaalsContact O-N 3.12Å; D315-K318 PolarHBondContact O-N 3.03Å; K318-T322 VanDerWaalsContact O-CB 3.32Å; K318-T322 WeakPolarHBondContact O-CB 3.43Å; K318-T322 PolarHBondContact O-N 2.89Å; K318-T322 PolarHBondContact O-OG1 3.31Å
319	M	48.2	Very low	53.3	Low	143 Å²	143	117.3 Å²	117.3	70%	0.704	59%	0.593	S	S	*	*	H	α-helix	trans	-67.4	-41.3	176.8	-76.3	-95.9	-79.8	0	0	112.5	D315 K316 T317 T322 A323	D315-M319 WeakPolarHBondContact O-CB 3.36Å; D315-M319 VanDerWaalsContact O-CG 3.29Å; D315-M319 WeakPolarHBondContact O-CG 3.33Å; D315-M319 PolarHBondContact O-N 3.48Å; K316-M319 PolarHBondContact O-N 3.3Å; T317-M319 PolarHBondContact O-N 2.84Å; M319-T322 PolarHBondContact O-N 3.31Å; M319-A323 WeakPolarHBondContact O-CB 3.05Å; M319-A323 PolarHBondContact O-N 2.77Å
320	I	49.8	Very low	50.8	Low	110 Å²	110	115.3 Å²	115.3	56%	0.564	59%	0.589	S	S	*	*	H	α-helix	trans	-66.4	-43.2	177.3	-68.6	163.2	0	0	0	110.7	K316 T317 A323 A324	K316-I320 WeakPolarHBondContact O-CB 3.48Å; K316-I320 VanDerWaalsContact O-CD1 3.32Å; K316-I320 WeakPolarHBondContact O-CD1 3.36Å; K316-I320 WeakPolarHBondContact O-CG1 3.48Å; K316-I320 PolarHBondContact O-N 2.99Å; T317-I320 PolarHBondContact O-N 3.23Å; I320-A323 PolarHBondContact O-N 3.26Å; I320-A324 VanDerWaalsContact O-CB 3.26Å; I320-A324 WeakPolarHBondContact O-CB 3.41Å; I320-A324 PolarHBondContact O-N 3.2Å
321	Y	48	Very low	48.5	Very low	163 Å²	163	113.1 Å²	113.1	64%	0.639	59%	0.592	S	S	*	*	H	α-helix	trans	-68.8	-38.8	178.9	-78.6	-112.2	0	0	0	111.2	T317 T325	T317-Y321 HydrophobicContact CG2-CD2 3.66Å; T317-Y321 HydrophobicContact CG2-CE2 3.3Å; T317-Y321 WeakPolarHBondContact O-CB 3.34Å; T317-Y321 WeakPolarHBondContact O-CD2 3.36Å; T317-Y321 PolarHBondContact O-N 2.96Å; Y321-T325 WeakPolarHBondContact O-CG2 3.19Å; Y321-T325 PolarHBondContact O-N 3.39Å; Y321-T325 PolarHBondContact O-OG1 3.35Å
322	T	50.4	Low	46.7	Very low	82 Å²	82	110.8 Å²	110.8	50%	0.503	60%	0.603	S	S	.	*	H	α-helix	trans	-67.2	-44.4	175.9	-51.5	0	0	0	0	111	K318 M319 T325 T326	K318-T322 VanDerWaalsContact O-CB 3.32Å; K318-T322 WeakPolarHBondContact O-CB 3.43Å; K318-T322 PolarHBondContact O-N 2.89Å; K318-T322 PolarHBondContact O-OG1 3.31Å; M319-T322 PolarHBondContact O-N 3.31Å; T322-T325 WeakPolarHBondContact CA-OG1 3.48Å; T322-T325 PolarHBondContact O-N 2.99Å; T322-T325 PolarHBondContact O-OG1 3.23Å; T322-T326 WeakPolarHBondContact O-CB 3.3Å; T322-T326 PolarHBondContact O-N 3.45Å; T322-T326 PolarHBondContact O-OG1 2.95Å
323	A	51.9	Low	45.4	Very low	49 Å²	49	112.6 Å²	112.6	41%	0.405	63%	0.625	S	S	.	*	H	α-helix	trans	-62.6	-44.4	176.8	0	0	0	0	0	112	M319 I320 T325 T326 E327	M319-A323 WeakPolarHBondContact O-CB 3.05Å; M319-A323 PolarHBondContact O-N 2.77Å; I320-A323 PolarHBondContact O-N 3.26Å; A323-T325 PolarHBondContact O-N 2.93Å; A323-T326 PolarHBondContact O-N 3.46Å; A323-T326 VanDerWaalsContact O-N 3.13Å; A323-E327 PolarHBondContact O-N 2.75Å
324	A	50.7	Low	44.5	Very low	50 Å²	50	117.6 Å²	117.6	41%	0.413	65%	0.646	S	S	.	*	H	α-helix	trans	-62.3	-41.3	175.7	0	0	0	0	0	112.3	I320 T326 E328	I320-A324 VanDerWaalsContact O-CB 3.26Å; I320-A324 WeakPolarHBondContact O-CB 3.41Å; I320-A324 PolarHBondContact O-N 3.2Å; A324-T326 VanDerWaalsContact C-N 3.29Å; A324-T326 PolarHBondContact O-N 2.72Å; A324-E328 PolarHBondContact O-N 2.61Å
325	T	50.4	Low	43.5	Very low	88 Å²	88	112.5 Å²	112.5	54%	0.54	65%	0.646	S	S	.	*	H	α-helix	trans	-69.1	-25.7	174.6	47.5	0	0	0	0	113.5	Y321 T322 A323 T329	Y321-T325 WeakPolarHBondContact O-CG2 3.19Å; Y321-T325 PolarHBondContact O-N 3.39Å; Y321-T325 PolarHBondContact O-OG1 3.35Å; T322-T325 WeakPolarHBondContact CA-OG1 3.48Å; T322-T325 PolarHBondContact O-N 2.99Å; T322-T325 PolarHBondContact O-OG1 3.23Å; A323-T325 PolarHBondContact O-N 2.93Å; T325-T329 PolarHBondContact O-OG1 2.95Å
326	T	46.8	Very low	42.5	Very low	75 Å²	75	115.8 Å²	115.8	46%	0.46	66%	0.663	S	S	.	*	H	α-helix	trans	-86.4	-31.9	-179.3	-40.8	0	0	0	0	111.7	T322 A323 A324 E328 T329	T322-T326 WeakPolarHBondContact O-CB 3.3Å; T322-T326 PolarHBondContact O-N 3.45Å; T322-T326 PolarHBondContact O-OG1 2.95Å; A323-T326 PolarHBondContact O-N 3.46Å; A323-T326 VanDerWaalsContact O-N 3.13Å; A324-T326 VanDerWaalsContact C-N 3.29Å; A324-T326 PolarHBondContact O-N 2.72Å; T326-E328 VanDerWaalsContact C-N 3.34Å; T326-T329 PolarHBondContact O-N 3.2Å
327	E	47.3	Very low	41.9	Very low	169 Å²	169	112.6 Å²	112.6	79%	0.79	67%	0.669	S	S	*	*	H	α-helix	trans	-70	-28.5	173.7	-80.8	-176.4	156.6	0	0	112.5	A323 T329	A323-E327 PolarHBondContact O-N 2.75Å; E327-T329 VanDerWaalsContact C-N 3.26Å; E327-T329 PolarHBondContact O-N 3.31Å
328	E	48.5	Very low	41	Very low	178 Å²	178	116 Å²	116	83%	0.832	69%	0.69	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76	-5.2	174	-77.2	-171.6	165.7	0	0	114.3	A324 T326	A324-E328 PolarHBondContact O-N 2.61Å; T326-E328 VanDerWaalsContact C-N 3.34Å
329	T	43.5	Very low	40.4	Very low	105 Å²	105	120.4 Å²	120.4	64%	0.644	71%	0.705	S	S	*	*	S	Bend	trans	-119.8	1.2	-173.4	20.6	0	0	0	0	119.1	T325 T326 E327	T325-T329 PolarHBondContact O-OG1 2.95Å; T326-T329 PolarHBondContact O-N 3.2Å; E327-T329 VanDerWaalsContact C-N 3.26Å; E327-T329 PolarHBondContact O-N 3.31Å
330	I	35.1	Very low	39.6	Very low	130 Å²	130	123 Å²	123	67%	0.667	71%	0.712	S	S	*	*			trans	-142.1	117.7	179.2	-50.7	180	0	0	0	113.8
331	P	35	Very low	38.6	Very low	124 Å²	124	121.2 Å²	121.2	81%	0.805	72%	0.72	S	S	*	*			trans	-82.7	124	161.5	16.5	-1.8	0	0	0	111.3
332	G	36	Very low	37.9	Very low	74 Å²	74	121 Å²	121	76%	0.763	73%	0.725	S	S	*	*			trans	75.6	111.4	151	0	0	0	0	0	119.2
333	A	30.1	Very low	37.2	Very low	106 Å²	106	123.4 Å²	123.4	88%	0.876	74%	0.735	S	S	*	*				171.1	135.7	126.9	0	0	0	0	0	112.1
334	L	34.3	Very low	36.6	Very low	181 Å²	181	124.5 Å²	124.5	95%	0.948	74%	0.739	S	S	*	*			trans	-59.5	154.4	174.7	-89.8	77.2	0	0	0	114.2
335	G	26.5	Very low	35.8	Very low	75 Å²	75	126.1 Å²	126.1	77%	0.773	75%	0.747	S	S	*	*			trans	163.2	100.9	149.5	0	0	0	0	0	118.1
336	N	27.9	Very low	35.1	Very low	173 Å²	173	127.5 Å²	127.5	93%	0.925	76%	0.758	S	S	*	*			trans	27.6	130.6	149.2	-75.9	-13.3	0	0	0	122.8
337	G	33.1	Very low	34.8	Very low	71 Å²	71	129.7 Å²	129.7	73%	0.732	78%	0.775	S	S	*	*			trans	-83.7	168.1	177.2	0	0	0	0	0	116.8
338	T	26.2	Very low	34.3	Very low	140 Å²	140	128 Å²	128	86%	0.859	78%	0.776	S	S	*	*			trans	-164.1	119.5	151.7	-5.3	0	0	0	0	109	K340	T338-K340 PolarHBondContact O-N 2.91Å
339	Y	29.1	Very low	33.9	Very low	243 Å²	243	128.1 Å²	128.1	95%	0.953	81%	0.807	S	S	*	*			trans	-72.4	114	172.5	-94.1	-97.6	0	0	0	109.7
340	K	30.6	Very low	33.4	Very low	198 Å²	198	129.3 Å²	129.3	86%	0.861	82%	0.815	S	S	*	*			trans	-96.5	131.1	166.5	-94.3	-178.6	173.6	177	0	109.7	T338	T338-K340 PolarHBondContact O-N 2.91Å
341	G	29.9	Very low	33.3	Very low	72 Å²	72	129.2 Å²	129.2	74%	0.742	82%	0.823	S	S	*	*			trans	-62.6	137.8	173.2	0	0	0	0	0	111.5	D343	G341-D343 PolarHBondContact O-N 3.15Å; G341-D343 VanDerWaalsContact O-N 3.12Å
342	E	33.6	Very low	33.2	Very low	159 Å²	159	129.5 Å²	129.5	74%	0.743	82%	0.824	S	S	*	*			trans	-68.8	106.6	176.6	-76.7	178.7	127.6	0	0	110.7	R249	R249-E342 IonicContact CZ-OE2 2.79Å; R249-E342 IonicContact NH1-OE2 2.73Å; R249-E342 IonicContact NH2-OE2 3.99Å; R249-E342 PolarHBondContact NH2-OE2 2.99Å
343	D	34.2	Very low	33.1	Very low	131 Å²	131	132.8 Å²	132.8	70%	0.701	83%	0.828	S	S	*	*			trans	-63.1	137.4	165.6	-91.4	-47.9	0	0	0	111.4	G341 S345	G341-D343 PolarHBondContact O-N 3.15Å; G341-D343 VanDerWaalsContact O-N 3.12Å; D343-S345 VanDerWaalsContact C-N 3.29Å; D343-S345 PolarHBondContact O-N 3.03Å
344	C	39	Very low	33.3	Very low	73 Å²	73	134.4 Å²	134.4	49%	0.493	83%	0.825	S	S	.	*			trans	-67	89.3	163.1	-76.9	0	0	0	0	109.3
345	S	34	Very low	33.2	Very low	83 Å²	83	131.3 Å²	131.3	58%	0.58	82%	0.817	S	S	*	*			trans	-83.4	140	167.1	-73.1	0	0	0	0	110.9	D343	D343-S345 VanDerWaalsContact C-N 3.29Å; D343-S345 PolarHBondContact O-N 3.03Å
346	P	35.9	Very low	33.7	Very low	118 Å²	118	135.4 Å²	135.4	77%	0.766	82%	0.82	S	S	*	*			trans	-83.6	137.9	164.3	33.1	-26.5	0	0	0	109.2
347	C	41.3	Very low	34.1	Very low	121 Å²	121	132.5 Å²	132.5	82%	0.818	81%	0.811	S	S	*	*			trans	-123.1	118.4	164.6	-78.8	0	0	0	0	111
348	T	37.1	Very low	34.2	Very low	134 Å²	134	137.6 Å²	137.6	82%	0.822	82%	0.818	S	S	*	*			trans	-10.2	135.7	150.2	40.2	0	0	0	0	119.2
349	A	39.3	Very low	34.9	Very low	179 Å²	179	137.4 Å²	137.4	100%	1.479	81%	0.814	S	S	*	*			trans	51.5	0	154	0	0	0	0	0	118.2

Retrieved 349 of 349 residues in 987.2 ms (Link to these results)

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