A0A0D9S0W4_CHLSB Loading...

Cystine/glutamate transporter

AlphaFold DB , UniProt , Accession A0A0D9S0W4, Species CHLSB (Chlorocebus sabaeus, Green monkey), Gene SLC7A11, Length 501 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.5	Very low	26.5	Very low	247 Å²	247	155.8 Å²	155.8	100%	1.217	85%	0.846	S	S	*	*				0	99.6	0	-87.5	176.8	175.3	0	0	109
2	V	26.5	Very low	26.6	Very low	146 Å²	146	159.3 Å²	159.3	89%	0.885	85%	0.848	S	S	*	*			trans	-140.8	117.2	167.9	178.5	0	0	0	0	105.8	K4	V2-K4 PolarHBondContact O-N 3.46Å
3	R	25.6	Very low	26.7	Very low	247 Å²	247	152.5 Å²	152.5	93%	0.932	84%	0.838	S	S	*	*	P	Polyproline II helix	trans	-66.6	124.3	-175.1	-79.7	176.6	171.2	175.3	-3.2	110
4	K	25.6	Very low	26.6	Very low	189 Å²	189	146.9 Å²	146.9	82%	0.822	83%	0.833	S	S	*	*	P	Polyproline II helix	trans	-65.8	138	161.4	-74	178	175.4	176.7	0	108.7	V2 V6	V2-K4 PolarHBondContact O-N 3.46Å; K4-V6 PolarHBondContact O-N 3.18Å
5	P	24.4	Very low	26.8	Very low	120 Å²	120	147.3 Å²	147.3	78%	0.779	82%	0.817	S	S	*	*	P	Polyproline II helix	trans	-70.9	117.3	164.7	28.2	-26	0	0	0	107.7	V7	P5-V7 PolarHBondContact O-N 3.26Å
6	V	26	Very low	27.2	Very low	135 Å²	135	149 Å²	149	82%	0.818	82%	0.824	S	S	*	*			trans	-71.3	104.6	170.4	175.8	0	0	0	0	106.5	K4 S8	K4-V6 PolarHBondContact O-N 3.18Å; V6-S8 PolarHBondContact O-N 2.91Å
7	V	25.5	Very low	27.1	Very low	133 Å²	133	152.3 Å²	152.3	81%	0.806	83%	0.832	S	S	*	*			trans	-69.7	108.9	162.1	177.3	0	0	0	0	105.5	P5 T9	P5-V7 PolarHBondContact O-N 3.26Å; V7-T9 PolarHBondContact O-N 3.32Å; V7-T9 VanDerWaalsContact O-N 3.16Å
8	S	23.4	Very low	27.1	Very low	94 Å²	94	147.5 Å²	147.5	66%	0.657	82%	0.823	S	S	*	*			trans	-53.3	119.2	172.4	49.7	0	0	0	0	108.7	V6 I10	V6-S8 PolarHBondContact O-N 2.91Å; S8-I10 PolarHBondContact O-N 3.41Å
9	T	26.6	Very low	27.2	Very low	136 Å²	136	148.1 Å²	148.1	83%	0.834	82%	0.824	S	S	*	*			trans	-39.7	123.9	160.5	22.7	0	0	0	0	109.2	V7 S11	V7-T9 PolarHBondContact O-N 3.32Å; V7-T9 VanDerWaalsContact O-N 3.16Å; T9-S11 PolarHBondContact O-N 3.43Å; T9-S11 VanDerWaalsContact O-N 3.15Å
10	I	28.8	Very low	27.3	Very low	165 Å²	165	147.1 Å²	147.1	85%	0.846	82%	0.822	S	S	*	*			trans	-42.3	120.2	174.9	-69.3	166	0	0	0	108.3	S8 K12	S8-I10 PolarHBondContact O-N 3.41Å; I10-K12 PolarHBondContact O-N 3.35Å
11	S	24.7	Very low	27.3	Very low	102 Å²	102	147.8 Å²	147.8	71%	0.713	82%	0.824	S	S	*	*			trans	-45.3	126.5	170.6	176.6	0	0	0	0	108.8	T9 G13	T9-S11 PolarHBondContact O-N 3.43Å; T9-S11 VanDerWaalsContact O-N 3.15Å; S11-G13 PolarHBondContact O-N 3.23Å
12	K	27.9	Very low	27	Very low	198 Å²	198	146.6 Å²	146.6	86%	0.861	81%	0.806	S	S	*	*			trans	-41.9	127.2	160.7	-72.4	-178.2	174	-176.1	0	107.9	I10 G14	I10-K12 PolarHBondContact O-N 3.35Å; K12-G14 PolarHBondContact O-N 3.34Å
13	G	27.3	Very low	27.2	Very low	70 Å²	70	151.9 Å²	151.9	72%	0.722	81%	0.81	S	S	*	*			trans	-54.1	114.5	178.7	0	0	0	0	0	109.8	S11 Y15	S11-G13 PolarHBondContact O-N 3.23Å; G13-Y15 VanDerWaalsContact C-N 3.27Å; G13-Y15 PolarHBondContact O-N 3.32Å
14	G	26	Very low	27.4	Very low	75 Å²	75	147.7 Å²	147.7	77%	0.773	81%	0.806	S	S	*	*			trans	-73.4	84.7	164.6	0	0	0	0	0	109.2	K12	K12-G14 PolarHBondContact O-N 3.34Å
15	Y	29.1	Very low	27.5	Very low	152 Å²	152	143.8 Å²	143.8	60%	0.596	80%	0.799	S	S	*	*			trans	-132.7	121.2	157.8	-83.4	-90.2	0	0	0	107.7	G13 R478	G13-Y15 VanDerWaalsContact C-N 3.27Å; G13-Y15 PolarHBondContact O-N 3.32Å; Y15-R478 PolarHBondContact OH-NE 3.08Å; Y15-R478 PolarHBondContact OH-NH2 3.32Å
16	L	33.4	Very low	28.2	Very low	175 Å²	175	144 Å²	144	92%	0.916	80%	0.803	S	S	*	*			trans	72.1	79.1	173.9	-55.2	168.2	0	0	0	116.8
17	Q	25.5	Very low	28.4	Very low	205 Å²	205	145.4 Å²	145.4	96%	0.958	81%	0.806	S	S	*	*			trans	-118.5	79.9	149.3	-120.1	170.7	-0.9	0	0	108.7
18	G	26.8	Very low	28.6	Very low	66 Å²	66	142.4 Å²	142.4	68%	0.68	80%	0.802	S	S	*	*			trans	-76.9	124.8	164.4	0	0	0	0	0	109.3	V20	G18-V20 PolarHBondContact O-N 2.88Å; G18-V20 VanDerWaalsContact O-N 3.16Å
19	N	30	Very low	29.2	Very low	158 Å²	158	146.2 Å²	146.2	85%	0.845	82%	0.815	S	S	*	*			trans	-51.2	112.4	172.7	-104.8	-20.3	0	0	0	111.5
20	V	28.9	Very low	29.5	Very low	129 Å²	129	149.2 Å²	149.2	78%	0.782	82%	0.816	S	S	*	*			trans	-132.9	75.4	160.7	-172.4	0	0	0	0	108.7	G18 R22	G18-V20 PolarHBondContact O-N 2.88Å; G18-V20 VanDerWaalsContact O-N 3.16Å; V20-R22 PolarHBondContact O-N 3.2Å
21	N	27.7	Very low	29.7	Very low	162 Å²	162	150.1 Å²	150.1	87%	0.866	82%	0.817	S	S	*	*			trans	-83.6	86.3	160.5	-98.3	-19	0	0	0	108.4
22	R	27.3	Very low	30.2	Very low	222 Å²	222	150 Å²	150	84%	0.838	81%	0.814	S	S	*	*			trans	-137.2	109.2	156.5	-95.2	-174	177	174.8	-0.7	108.6	V20 L24	V20-R22 PolarHBondContact O-N 3.2Å; R22-L24 PolarHBondContact O-N 2.96Å
23	R	31	Very low	30.5	Very low	257 Å²	257	146.9 Å²	146.9	97%	0.97	81%	0.814	S	S	*	*			trans	-58.2	122.7	168.2	-72.1	179.5	-178.8	-178.5	-0.4	108.5
24	L	29	Very low	31.2	Very low	159 Å²	159	147.1 Å²	147.1	83%	0.832	82%	0.816	S	S	*	*			trans	-113.2	144.6	161.7	-83.4	159.5	0	0	0	108.6	R22	R22-L24 PolarHBondContact O-N 2.96Å
25	P	28.9	Very low	31.9	Very low	106 Å²	106	151.1 Å²	151.1	69%	0.688	82%	0.815	S	S	*	*			trans	-69.5	146.4	-170.5	-11.9	27.4	0	0	0	112.2	L27	P25-L27 PolarHBondContact O-N 2.92Å
26	S	38.2	Very low	32.6	Very low	124 Å²	124	150.7 Å²	150.7	87%	0.867	82%	0.818	S	S	*	*			trans	-55.8	112.2	173.4	53.1	0	0	0	0	111.8
27	L	31.2	Very low	33.5	Very low	166 Å²	166	149.6 Å²	149.6	87%	0.869	81%	0.806	S	S	*	*			trans	-116	113.5	166.9	-90.2	153.1	0	0	0	108.6	P25	P25-L27 PolarHBondContact O-N 2.92Å
28	G	28.9	Very low	34.8	Very low	70 Å²	70	141.8 Å²	141.8	72%	0.722	77%	0.772	S	S	*	*			trans	17.6	117.7	163.9	0	0	0	0	0	119.3	K30	G28-K30 PolarHBondContact O-N 3.11Å
29	N	35.4	Very low	36.4	Very low	174 Å²	174	142.7 Å²	142.7	93%	0.93	76%	0.759	S	S	*	*			trans	-49.6	98.9	158.4	-79.6	-12.9	0	0	0	111.1
30	K	32.7	Very low	37.9	Very low	198 Å²	198	137.9 Å²	137.9	86%	0.861	73%	0.733	S	S	*	*			trans	-127	103.2	148.5	-79.2	-173.4	176.1	-180	0	106.2	G28	G28-K30 PolarHBondContact O-N 3.11Å
31	E	33.8	Very low	39.7	Very low	184 Å²	184	137.4 Å²	137.4	86%	0.86	72%	0.72	S	S	*	*	P	Polyproline II helix	trans	-53.4	127.6	165.9	-70.1	179.8	159.9	0	0	108.1
32	P	34.4	Very low	41.8	Very low	100 Å²	100	138.8 Å²	138.8	65%	0.649	71%	0.713	S	S	*	*	P	Polyproline II helix	trans	-63.8	135.5	173	24.7	-30.2	0	0	0	109	G34	P32-G34 PolarHBondContact O-N 3.47Å
33	P	35.7	Very low	44.2	Very low	133 Å²	133	132.9 Å²	132.9	86%	0.864	69%	0.693	S	S	*	*	S	Bend	trans	-68.9	118.4	-178.8	27.2	-32.2	0	0	0	110.3
34	G	42.3	Very low	46.5	Very low	75 Å²	75	121 Å²	121	77%	0.773	65%	0.65	S	S	*	*			trans	86.1	53	155.8	0	0	0	0	0	117.8	P32 E36	P32-G34 PolarHBondContact O-N 3.47Å; G34-E36 PolarHBondContact O-N 3.44Å
35	Q	39.1	Very low	49.4	Very low	158 Å²	158	115.8 Å²	115.8	74%	0.738	62%	0.624	S	S	*	*			trans	-78.8	93.6	149.4	-91.9	175.3	-38.3	0	0	108	K37	Q35-K37 PolarHBondContact O-N 3.31Å
36	E	45	Very low	52.2	Low	144 Å²	144	113.5 Å²	113.5	67%	0.673	61%	0.606	S	S	*	*			trans	-58.2	106.8	165.6	-89.6	-163.2	127.8	0	0	107.9	G34 V38 K41	G34-E36 PolarHBondContact O-N 3.44Å; E36-V38 PolarHBondContact O-N 3.21Å; E36-K41 IonicContact OE1-NZ 3.21Å; E36-K41 PolarHBondContact OE1-NZ 2.78Å
37	K	51.2	Low	54.5	Low	151 Å²	151	114 Å²	114	66%	0.657	60%	0.598	S	S	*	*			trans	-52.3	123.3	172.5	-66.2	-175.6	177.7	-175.1	0	109.1	Q35 Q39	Q35-K37 PolarHBondContact O-N 3.31Å; K37-Q39 VanDerWaalsContact C-N 3.32Å; K37-Q39 HydrophobicContact CB-CG 4.3Å; K37-Q39 PolarHBondContact O-N 3.04Å
38	V	53.4	Low	57	Low	41 Å²	41	111.1 Å²	111.1	25%	0.248	58%	0.576	C	S	.	*			trans	-76.9	85.8	-179.2	-176	0	0	0	0	108.7	E36 I358	E36-V38 PolarHBondContact O-N 3.21Å; V38-I358 HydrophobicContact CG1-CD1 4.24Å
39	Q	59.6	Low	59.8	Low	86 Å²	86	107.8 Å²	107.8	40%	0.402	54%	0.542	S	S	.	.			trans	-123	153	178.7	-66	-176.4	-1.1	0	0	111.8	K37 K41	K37-Q39 VanDerWaalsContact C-N 3.32Å; K37-Q39 HydrophobicContact CB-CG 4.3Å; K37-Q39 PolarHBondContact O-N 3.04Å; Q39-K41 PolarHBondContact O-N 3.18Å
40	L	61.9	Low	62.3	Low	57 Å²	57	100.7 Å²	100.7	30%	0.298	50%	0.503	S	S	.	.			trans	-66.5	114.2	172	-69.8	169.3	0	0	0	110.1	E258 Y343	L40-E258 HydrophobicContact CB-CG 4.36Å; L40-Y343 HydrophobicContact CD1-CE1 4.13Å
41	K	66.3	Low	64.8	Low	118 Å²	118	91.8 Å²	91.8	51%	0.513	47%	0.466	S	S	.	.			trans	-75.1	133.1	-178.3	-64.2	-175.2	177.8	-176.8	0	110.4	E36 Q39 K43	E36-K41 IonicContact OE1-NZ 3.21Å; E36-K41 PolarHBondContact OE1-NZ 2.78Å; Q39-K41 PolarHBondContact O-N 3.18Å; K41-K43 HydrophobicContact CB-CD 4.04Å; K41-K43 HydrophobicContact CB-CG 4.03Å; K41-K43 PolarHBondContact O-N 2.65Å
42	R	72.7	Confident	67.1	Low	191 Å²	191	84.2 Å²	84.2	72%	0.721	43%	0.431	S	S	*	.			trans	-62.9	105.2	170.7	-70.5	-176.7	-177.7	172.9	3.7	110.2	E257 E258	R42-E257 WeakPolarHBondContact CG-O 3.48Å; R42-E258 CarbonylContact C-O 3.3Å; R42-E258 WeakPolarHBondContact CA-O 3.28Å
43	K	76.7	Confident	69.7	Low	98 Å²	98	79.5 Å²	79.5	43%	0.426	40%	0.4	S	S	.	.			trans	-135.7	-3.3	-170.7	-76.2	-178.7	174.4	178.2	0	113.5	K41 T45 R48 E258	K41-K43 HydrophobicContact CB-CD 4.04Å; K41-K43 HydrophobicContact CB-CG 4.03Å; K41-K43 PolarHBondContact O-N 2.65Å; K43-T45 PolarHBondContact O-N 2.9Å; K43-R48 VanDerWaalsContact O-CD 3.26Å; K43-R48 WeakPolarHBondContact O-CD 3.42Å; K43-R48 PolarHBondContact O-NH1 3.32Å; K43-E258 PolarHBondContact N-O 3.01Å
44	V	81.3	Confident	72.2	Confident	8 Å²	8	73.4 Å²	73.4	5%	0.048	36%	0.36	C	S	.	.	B	Isolated β-bridge	trans	-93.7	95.9	-178.3	-176.3	0	0	0	0	109.1	R48 I52 L252 E258 V259 E260	V44-R48 HydrophobicContact CG1-CB 4.1Å; V44-I52 HydrophobicContact CG1-CD1 3.96Å; V44-I52 HydrophobicContact CG2-CD1 4.42Å; V44-L252 HydrophobicContact CG1-CD1 4.02Å; V44-E258 HydrophobicContact CG2-CB 4.03Å; V44-E258 PolarHBondContact N-O 2.94Å; V44-V259 HydrophobicContact CB-CG2 4.16Å; V44-V259 HydrophobicContact CG1-CG2 4.16Å; V44-E260 PolarHBondContact O-N 2.77Å
45	T	88.9	Confident	74.1	Confident	49 Å²	49	69.8 Å²	69.8	30%	0.301	32%	0.324	S	S	.	.			trans	-74.8	171	172.3	62.5	0	0	0	0	111.2	K43 L47 R48 G49	K43-T45 PolarHBondContact O-N 2.9Å; T45-L47 PolarHBondContact O-N 2.97Å; T45-R48 PolarHBondContact O-N 3.2Å; T45-R48 VanDerWaalsContact O-N 3.13Å; T45-R48 WeakPolarHBondContact OG1-CG 3.43Å; T45-G49 PolarHBondContact O-N 3.28Å
46	L	88.8	Confident	76.2	Confident	58 Å²	58	62.9 Å²	62.9	30%	0.304	29%	0.292	S	S	.	.	H	α-helix	trans	-53	-49.2	177.3	178.5	66	0	0	0	113.6	R48 G49 I50 T265 L268 A269	L46-R48 VanDerWaalsContact C-N 3.3Å; L46-R48 PolarHBondContact O-N 3.16Å; L46-G49 PolarHBondContact O-N 3.15Å; L46-G49 VanDerWaalsContact O-N 3.13Å; L46-I50 HydrophobicContact CD1-CD1 4.15Å; L46-I50 HydrophobicContact CD1-CG1 4.38Å; L46-I50 HydrophobicContact CG-CD1 4Å; L46-I50 WeakPolarHBondContact O-CG1 3.18Å; L46-I50 PolarHBondContact O-N 3.22Å; L46-T265 HydrophobicContact CB-CG2 4.26Å; L46-T265 HydrophobicContact CD1-CG2 4.2Å; L46-L268 HydrophobicContact CD1-CB 4.04Å; L46-L268 HydrophobicContact CD1-CD2 3.91Å; L46-L268 HydrophobicContact CD1-CG 4.01Å; L46-L268 HydrophobicContact CD2-CD2 3.51Å; L46-L268 HydrophobicContact CD2-CG 4.34Å; L46-L268 HydrophobicContact CG-CD2 4.37Å; L46-A269 HydrophobicContact CD1-CB 4.04Å
47	L	85.9	Confident	78.3	Confident	135 Å²	135	56.2 Å²	56.2	71%	0.707	26%	0.261	S	S	*	.	H	α-helix	trans	-62.7	-38.9	179.4	-175.1	67	0	0	0	111.8	T45 I50 S51	T45-L47 PolarHBondContact O-N 2.97Å; L47-I50 PolarHBondContact O-N 2.93Å; L47-S51 WeakPolarHBondContact O-CB 3.45Å; L47-S51 PolarHBondContact O-N 3.14Å
48	R	83.7	Confident	80	Confident	106 Å²	106	49.2 Å²	49.2	40%	0.4	23%	0.231	S	C	.	.	H	α-helix	trans	-66.2	-39.6	174.4	-68.3	-179.6	-179.4	-179.5	0.1	111.2	K43 V44 T45 L46 S51 I52 I192	K43-R48 VanDerWaalsContact O-CD 3.26Å; K43-R48 WeakPolarHBondContact O-CD 3.42Å; K43-R48 PolarHBondContact O-NH1 3.32Å; V44-R48 HydrophobicContact CG1-CB 4.1Å; T45-R48 PolarHBondContact O-N 3.2Å; T45-R48 VanDerWaalsContact O-N 3.13Å; T45-R48 WeakPolarHBondContact OG1-CG 3.43Å; L46-R48 VanDerWaalsContact C-N 3.3Å; L46-R48 PolarHBondContact O-N 3.16Å; R48-S51 PolarHBondContact O-N 3.5Å; R48-I52 WeakPolarHBondContact O-CB 3.48Å; R48-I52 VanDerWaalsContact O-CG1 3.23Å; R48-I52 WeakPolarHBondContact O-CG1 3.31Å; R48-I52 PolarHBondContact O-N 2.86Å; R48-I192 HydrophobicContact CG-CD1 4.34Å
49	G	86.4	Confident	81.4	Confident	0 Å²	0	47.4 Å²	47.4	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-61	-48.6	174.6	0	0	0	0	0	112.3	T45 L46 S51 I52 I53	T45-G49 PolarHBondContact O-N 3.28Å; L46-G49 PolarHBondContact O-N 3.15Å; L46-G49 VanDerWaalsContact O-N 3.13Å; G49-S51 VanDerWaalsContact C-N 3.32Å; G49-S51 PolarHBondContact O-N 2.62Å; G49-I52 PolarHBondContact O-N 2.87Å; G49-I53 WeakPolarHBondContact O-CG1 3.12Å; G49-I53 PolarHBondContact O-N 3.16Å
50	I	88.8	Confident	82.3	Confident	25 Å²	25	43.4 Å²	43.4	13%	0.128	20%	0.202	C	C	.	.	H	α-helix	trans	-58.9	-44.9	174.9	-68.1	167.6	0	0	0	110.5	L46 L47 I53 I54 A269 I272 S273	L46-I50 HydrophobicContact CD1-CD1 4.15Å; L46-I50 HydrophobicContact CD1-CG1 4.38Å; L46-I50 HydrophobicContact CG-CD1 4Å; L46-I50 WeakPolarHBondContact O-CG1 3.18Å; L46-I50 PolarHBondContact O-N 3.22Å; L47-I50 PolarHBondContact O-N 2.93Å; I50-I53 PolarHBondContact O-N 3.32Å; I50-I54 HydrophobicContact CG2-CD1 3.56Å; I50-I54 HydrophobicContact CG2-CG1 4.22Å; I50-I54 WeakPolarHBondContact O-CB 3.45Å; I50-I54 WeakPolarHBondContact O-CG1 3.38Å; I50-I54 PolarHBondContact O-N 3.17Å; I50-A269 HydrophobicContact CG1-CB 3.98Å; I50-I272 HydrophobicContact CD1-CB 4.39Å; I50-I272 HydrophobicContact CD1-CD1 4.06Å; I50-I272 HydrophobicContact CD1-CG2 4.11Å; I50-S273 PolarHBondContact O-OG 2.87Å
51	S	84.5	Confident	83.5	Confident	11 Å²	11	41 Å²	41	8%	0.077	19%	0.191	C	C	.	.	H	α-helix	trans	-65	-38.6	178.3	171.6	0	0	0	0	112.9	L47 R48 G49 G55 T195	L47-S51 WeakPolarHBondContact O-CB 3.45Å; L47-S51 PolarHBondContact O-N 3.14Å; R48-S51 PolarHBondContact O-N 3.5Å; G49-S51 VanDerWaalsContact C-N 3.32Å; G49-S51 PolarHBondContact O-N 2.62Å; S51-G55 VanDerWaalsContact O-CA 3.28Å; S51-G55 WeakPolarHBondContact O-CA 3.29Å; S51-G55 PolarHBondContact O-N 3.42Å; S51-T195 PolarHBondContact O-OG1 3.24Å; S51-T195 PolarHBondContact OG-OG1 3.19Å
52	I	83.1	Confident	84.7	Confident	25 Å²	25	35.3 Å²	35.3	13%	0.128	17%	0.166	C	C	.	.	H	α-helix	trans	-63.9	-45.8	174.9	-71.4	164.5	0	0	0	110	V44 R48 G49 T56	V44-I52 HydrophobicContact CG1-CD1 3.96Å; V44-I52 HydrophobicContact CG2-CD1 4.42Å; R48-I52 WeakPolarHBondContact O-CB 3.48Å; R48-I52 VanDerWaalsContact O-CG1 3.23Å; R48-I52 WeakPolarHBondContact O-CG1 3.31Å; R48-I52 PolarHBondContact O-N 2.86Å; G49-I52 PolarHBondContact O-N 2.87Å; I52-T56 WeakPolarHBondContact O-CB 3.34Å; I52-T56 VanDerWaalsContact O-CG2 3.23Å; I52-T56 WeakPolarHBondContact O-CG2 3.17Å; I52-T56 PolarHBondContact O-N 3.26Å; I52-T56 PolarHBondContact O-OG1 2.82Å
53	I	88.1	Confident	85.3	Confident	0 Å²	0	26.4 Å²	26.4	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-66.7	-54.3	-179.2	-65	170.9	0	0	0	110.8	G49 I50 G55 T56 I57 L252 A269 I270	G49-I53 WeakPolarHBondContact O-CG1 3.12Å; G49-I53 PolarHBondContact O-N 3.16Å; I50-I53 PolarHBondContact O-N 3.32Å; I53-G55 VanDerWaalsContact C-N 3.31Å; I53-G55 PolarHBondContact O-N 2.92Å; I53-T56 PolarHBondContact O-N 3.44Å; I53-T56 VanDerWaalsContact O-N 3.17Å; I53-T56 PolarHBondContact O-OG1 2.71Å; I53-I57 HydrophobicContact CG2-CD1 3.47Å; I53-I57 VanDerWaalsContact CG2-CD1 3.47Å; I53-I57 HydrophobicContact CG2-CG1 4.26Å; I53-I57 WeakPolarHBondContact O-CG1 3.22Å; I53-I57 PolarHBondContact O-N 3.32Å; I53-L252 HydrophobicContact CD1-CB 4.04Å; I53-L252 HydrophobicContact CD1-CD2 3.84Å; I53-L252 HydrophobicContact CG1-CB 4.04Å; I53-A269 HydrophobicContact CD1-CB 3.92Å; I53-I270 HydrophobicContact CD1-CG1 3.72Å
54	I	88.8	Confident	85.7	Confident	5 Å²	5	23.5 Å²	23.5	3%	0.026	12%	0.121	C	C	.	.	H	α-helix	trans	-60	-45.6	178.7	-67.8	178.6	0	0	0	110.2	I50 T56 I57 I58 T195 L199 I276	I50-I54 HydrophobicContact CG2-CD1 3.56Å; I50-I54 HydrophobicContact CG2-CG1 4.22Å; I50-I54 WeakPolarHBondContact O-CB 3.45Å; I50-I54 WeakPolarHBondContact O-CG1 3.38Å; I50-I54 PolarHBondContact O-N 3.17Å; I54-T56 PolarHBondContact O-N 3.4Å; I54-I57 PolarHBondContact O-N 3.1Å; I54-I58 HydrophobicContact CG2-CD1 3.58Å; I54-I58 HydrophobicContact CG2-CG1 4.09Å; I54-I58 VanDerWaalsContact O-CB 3.31Å; I54-I58 WeakPolarHBondContact O-CB 3.24Å; I54-I58 PolarHBondContact O-N 3.45Å; I54-T195 HydrophobicContact CB-CG2 4.23Å; I54-T195 HydrophobicContact CG2-CG2 3.92Å; I54-L199 HydrophobicContact CG2-CD2 3.96Å; I54-L199 HydrophobicContact CG2-CG 4.41Å; I54-I276 HydrophobicContact CD1-CB 4.45Å; I54-I276 HydrophobicContact CD1-CD1 3.99Å; I54-I276 HydrophobicContact CD1-CG2 4.19Å
55	G	82.8	Confident	86.2	Confident	0 Å²	0	23.1 Å²	23.1	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-69.6	-10.8	-178.8	0	0	0	0	0	114.3	S51 I53 Q191 K198	S51-G55 VanDerWaalsContact O-CA 3.28Å; S51-G55 WeakPolarHBondContact O-CA 3.29Å; S51-G55 PolarHBondContact O-N 3.42Å; I53-G55 VanDerWaalsContact C-N 3.31Å; I53-G55 PolarHBondContact O-N 2.92Å; G55-Q191 PolarHBondContact O-NE2 2.97Å; G55-K198 PolarHBondContact O-NZ 3.06Å
56	T	82.7	Confident	86.4	Confident	12 Å²	12	20.9 Å²	20.9	7%	0.074	11%	0.105	C	C	.	.	H	α-helix	trans	-103.1	-35.7	172.9	49.6	0	0	0	0	112.6	I52 I53 I54 Y251	I52-T56 WeakPolarHBondContact O-CB 3.34Å; I52-T56 VanDerWaalsContact O-CG2 3.23Å; I52-T56 WeakPolarHBondContact O-CG2 3.17Å; I52-T56 PolarHBondContact O-N 3.26Å; I52-T56 PolarHBondContact O-OG1 2.82Å; I53-T56 PolarHBondContact O-N 3.44Å; I53-T56 VanDerWaalsContact O-N 3.17Å; I53-T56 PolarHBondContact O-OG1 2.71Å; I54-T56 PolarHBondContact O-N 3.4Å; T56-Y251 HydrophobicContact CG2-CD2 3.66Å; T56-Y251 HydrophobicContact CG2-CE2 4.1Å; T56-Y251 HydrophobicContact CG2-CG 4.11Å; T56-Y251 WeakPolarHBondContact OG1-CD2 3.26Å
57	I	89.3	Confident	86.5	Confident	5 Å²	5	20.9 Å²	20.9	3%	0.026	10%	0.103	C	C	.	.	H	α-helix	trans	-72.5	-52.3	176.1	-60	168.1	0	0	0	110.9	I53 I54 G59 W249 M274 V277 Y281	I53-I57 HydrophobicContact CG2-CD1 3.47Å; I53-I57 VanDerWaalsContact CG2-CD1 3.47Å; I53-I57 HydrophobicContact CG2-CG1 4.26Å; I53-I57 WeakPolarHBondContact O-CG1 3.22Å; I53-I57 PolarHBondContact O-N 3.32Å; I54-I57 PolarHBondContact O-N 3.1Å; I57-G59 PolarHBondContact O-N 3.09Å; I57-W249 HydrophobicContact CD1-CB 3.85Å; I57-M274 HydrophobicContact CD1-SD 3.74Å; I57-V277 HydrophobicContact CB-CG2 4.29Å; I57-V277 HydrophobicContact CD1-CG2 4.29Å; I57-V277 HydrophobicContact CG2-CB 4.49Å; I57-V277 HydrophobicContact CG2-CG1 3.64Å; I57-V277 HydrophobicContact CG2-CG2 4.13Å; I57-Y281 HydrophobicContact CG2-CE2 4.49Å; I57-Y281 PolarHBondContact O-OH 3.43Å
58	I	87.1	Confident	86.7	Confident	3 Å²	3	14.7 Å²	14.7	2%	0.015	7%	0.072	C	C	.	.	S	Bend	trans	-74	101.4	179.4	-56.1	-173.2	0	0	0	107.9	I54 K198 L199 I202 V277 Y281 S330	I54-I58 HydrophobicContact CG2-CD1 3.58Å; I54-I58 HydrophobicContact CG2-CG1 4.09Å; I54-I58 VanDerWaalsContact O-CB 3.31Å; I54-I58 WeakPolarHBondContact O-CB 3.24Å; I54-I58 PolarHBondContact O-N 3.45Å; I58-K198 HydrophobicContact CG2-CB 4.14Å; I58-K198 WeakPolarHBondContact O-CD 3.42Å; I58-K198 PolarHBondContact O-NZ 3.33Å; I58-L199 HydrophobicContact CD1-CD2 4.08Å; I58-I202 HydrophobicContact CB-CD1 4.49Å; I58-I202 HydrophobicContact CD1-CD1 3.65Å; I58-I202 HydrophobicContact CG1-CD1 4.3Å; I58-I202 HydrophobicContact CG2-CD1 3.47Å; I58-I202 VanDerWaalsContact CG2-CD1 3.47Å; I58-I202 HydrophobicContact CG2-CG1 4.44Å; I58-V277 HydrophobicContact CD1-CG2 4.05Å; I58-V277 HydrophobicContact CG1-CG2 3.86Å; I58-Y281 WeakPolarHBondContact CA-OH 3.41Å; I58-Y281 HydrophobicContact CG1-CE1 4.1Å; I58-S330 PolarHBondContact O-OG 3.06Å
59	G	81.7	Confident	87.1	Confident	3 Å²	3	9.7 Å²	9.7	3%	0.031	5%	0.053	C	C	.	.	S	Bend	trans	-150.2	-142.4	-177.3	0	0	0	0	0	111.5	I57 G61 F63 S330	I57-G59 PolarHBondContact O-N 3.09Å; G59-G61 PolarHBondContact O-N 3.02Å; G59-F63 WeakPolarHBondContact O-CD2 3.2Å; G59-F63 WeakPolarHBondContact O-CE2 3.45Å; G59-S330 WeakPolarHBondContact CA-OG 3.2Å
60	A	78.5	Confident	87.5	Confident	2 Å²	2	9.9 Å²	9.9	2%	0.017	5%	0.054	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.2	-28.1	178.3	0	0	0	0	0	113.1	I62 F63 I64 A145	A60-I62 PolarHBondContact O-N 3.35Å; A60-F63 PolarHBondContact O-N 2.68Å; A60-I64 HydrophobicContact CB-CD1 3.88Å; A60-I64 WeakPolarHBondContact O-CG1 3.32Å; A60-I64 PolarHBondContact O-N 3.18Å; A60-I64 VanDerWaalsContact O-N 3.08Å; A60-A145 HydrophobicContact CB-CB 3.52Å
61	G	87.2	Confident	87.6	Confident	6 Å²	6	14 Å²	14	6%	0.062	7%	0.073	C	C	.	.	H	α-helix	trans	-56.6	-46.7	-173	0	0	0	0	0	114.9	G59 F63 I64 S65	G59-G61 PolarHBondContact O-N 3.02Å; G61-F63 PolarHBondContact O-N 2.79Å; G61-I64 PolarHBondContact O-N 2.82Å; G61-S65 WeakPolarHBondContact O-CB 3.46Å; G61-S65 PolarHBondContact O-N 3Å; G61-S65 PolarHBondContact O-OG 3.04Å; G61-S65 VanDerWaalsContact O-OG 3.08Å
62	I	91.7	Very high	87.8	Confident	0 Å²	0	14.6 Å²	14.6	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-67.6	-18.8	179.5	-170.6	53.9	0	0	0	113.5	A60 P66 W83 Y281 T284	A60-I62 PolarHBondContact O-N 3.35Å; I62-P66 WeakPolarHBondContact O-CD 3.42Å; I62-P66 WeakPolarHBondContact O-CG 3.44Å; I62-W83 HydrophobicContact CD1-CH2 3.5Å; I62-W83 HydrophobicContact CD1-CZ2 4.07Å; I62-W83 HydrophobicContact CD1-CZ3 3.77Å; I62-Y281 HydrophobicContact CB-CD1 3.96Å; I62-Y281 HydrophobicContact CB-CE1 3.57Å; I62-Y281 HydrophobicContact CD1-CD1 3.62Å; I62-Y281 HydrophobicContact CD1-CD2 4.21Å; I62-Y281 HydrophobicContact CD1-CE1 4.15Å; I62-Y281 HydrophobicContact CD1-CG 3.64Å; I62-Y281 HydrophobicContact CG1-CD1 3.61Å; I62-Y281 HydrophobicContact CG1-CE1 3.77Å; I62-Y281 HydrophobicContact CG1-CG 4.17Å; I62-Y281 HydrophobicContact CG2-CE1 4.04Å; I62-T284 HydrophobicContact CD1-CG2 4.28Å; I62-T284 HydrophobicContact CG1-CG2 4.04Å
63	F	86.5	Confident	88.2	Confident	3 Å²	3	13.7 Å²	13.7	1%	0.013	7%	0.071	C	C	.	.	H	α-helix	trans	-97.3	-14.8	-179.6	-53.3	-63.9	0	0	0	113.1	G59 A60 G61 Y149 I205 A304 V323	G59-F63 WeakPolarHBondContact O-CD2 3.2Å; G59-F63 WeakPolarHBondContact O-CE2 3.45Å; A60-F63 PolarHBondContact O-N 2.68Å; G61-F63 PolarHBondContact O-N 2.79Å; F63-Y149 HydrophobicContact CB-CE2 4.16Å; F63-Y149 WeakPolarHBondContact CB-OH 3.39Å; F63-Y149 PolarHBondContact O-OH 3.17Å; F63-I205 HydrophobicContact CE1-CD1 3.99Å; F63-A304 HydrophobicContact CD1-CB 3.83Å; F63-A304 HydrophobicContact CE1-CB 4.28Å; F63-V323 HydrophobicContact CB-CG1 4.27Å; F63-V323 HydrophobicContact CD1-CG1 4.29Å; F63-V323 HydrophobicContact CD1-CG2 3.93Å; F63-V323 HydrophobicContact CD2-CB 4.44Å; F63-V323 HydrophobicContact CD2-CG1 3.47Å; F63-V323 VanDerWaalsContact CD2-CG1 3.47Å; F63-V323 HydrophobicContact CD2-CG2 4.3Å; F63-V323 HydrophobicContact CE1-CG2 3.66Å; F63-V323 HydrophobicContact CE2-CB 4.32Å; F63-V323 HydrophobicContact CE2-CG1 3.78Å; F63-V323 HydrophobicContact CE2-CG2 4.05Å; F63-V323 HydrophobicContact CG-CG1 3.75Å; F63-V323 HydrophobicContact CG-CG2 4.24Å; F63-V323 HydrophobicContact CZ-CB 4.46Å; F63-V323 HydrophobicContact CZ-CG1 4.32Å; F63-V323 HydrophobicContact CZ-CG2 3.73Å
64	I	84.4	Confident	88.2	Confident	38 Å²	38	15.2 Å²	15.2	20%	0.195	9%	0.086	C	C	.	.	H	α-helix	trans	-105.6	-47.4	179.1	-63.6	171.5	0	0	0	110.8	A60 G61 A145 L385	A60-I64 HydrophobicContact CB-CD1 3.88Å; A60-I64 WeakPolarHBondContact O-CG1 3.32Å; A60-I64 PolarHBondContact O-N 3.18Å; A60-I64 VanDerWaalsContact O-N 3.08Å; G61-I64 PolarHBondContact O-N 2.82Å; I64-A145 HydrophobicContact CD1-CB 4.02Å; I64-L385 HydrophobicContact CD1-CD1 4.34Å
65	S	91.3	Very high	88.3	Confident	0 Å²	0	15.1 Å²	15.1	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-62.6	-30.1	-172	-65.2	0	0	0	0	116.4	G61 K67 G68 V69 Y241	G61-S65 WeakPolarHBondContact O-CB 3.46Å; G61-S65 PolarHBondContact O-N 3Å; G61-S65 PolarHBondContact O-OG 3.04Å; G61-S65 VanDerWaalsContact O-OG 3.08Å; S65-K67 VanDerWaalsContact C-N 3.28Å; S65-K67 PolarHBondContact O-N 3.49Å; S65-G68 PolarHBondContact O-N 2.98Å; S65-G68 VanDerWaalsContact O-N 3.14Å; S65-V69 WeakPolarHBondContact O-CG2 3.43Å; S65-V69 PolarHBondContact O-N 3.31Å; S65-Y241 VanDerWaalsContact CB-O 3.29Å; S65-Y241 WeakPolarHBondContact CB-O 3.49Å; S65-Y241 PolarHBondContact OG-O 3.36Å
66	P	93.6	Very high	88.8	Confident	2 Å²	2	15.8 Å²	15.8	1%	0.013	9%	0.09	C	C	.	.	H	α-helix	trans	-53.6	-42.9	-178.6	-29.2	35.6	0	0	0	113.7	I62 V69 L70 W83 Y288 L297	I62-P66 WeakPolarHBondContact O-CD 3.42Å; I62-P66 WeakPolarHBondContact O-CG 3.44Å; P66-V69 PolarHBondContact O-N 3.32Å; P66-L70 WeakPolarHBondContact O-CB 3.29Å; P66-L70 PolarHBondContact O-N 3.03Å; P66-W83 HydrophobicContact CG-CZ2 4.02Å; P66-Y288 HydrophobicContact CB-CD2 4.41Å; P66-Y288 HydrophobicContact CB-CE2 4.42Å; P66-Y288 HydrophobicContact CG-CD2 4.37Å; P66-Y288 HydrophobicContact CG-CE2 3.95Å; P66-L297 HydrophobicContact CB-CD2 4.49Å
67	K	91.4	Very high	89.3	Confident	58 Å²	58	15.5 Å²	15.5	25%	0.252	9%	0.089	S	C	.	.	H	α-helix	trans	-61.6	-50.5	176.7	176.1	170.2	177.6	163.1	0	111.6	S65 V69 L70 Q71 L297 L298 S300	S65-K67 VanDerWaalsContact C-N 3.28Å; S65-K67 PolarHBondContact O-N 3.49Å; K67-V69 PolarHBondContact O-N 3.08Å; K67-L70 PolarHBondContact O-N 3.05Å; K67-Q71 VanDerWaalsContact O-CB 3.25Å; K67-Q71 WeakPolarHBondContact O-CB 3.38Å; K67-Q71 PolarHBondContact O-N 3.22Å; K67-L297 HydrophobicContact CB-CD2 4.22Å; K67-L298 WeakPolarHBondContact CE-O 3.29Å; K67-L298 HydrophobicContact CG-CD2 4.46Å; K67-L298 PolarHBondContact NZ-O 3.37Å; K67-S300 WeakPolarHBondContact CD-O 3.25Å; K67-S300 PolarHBondContact NZ-O 3.06Å
68	G	89.1	Confident	89.5	Confident	5 Å²	5	17.9 Å²	17.9	5%	0.052	10%	0.101	C	C	.	.	H	α-helix	trans	-63	-39.8	178.8	0	0	0	0	0	113.2	S65 N72	S65-G68 PolarHBondContact O-N 2.98Å; S65-G68 VanDerWaalsContact O-N 3.14Å; G68-N72 WeakPolarHBondContact O-CB 3.23Å; G68-N72 PolarHBondContact O-N 2.65Å; G68-N72 PolarHBondContact O-ND2 2.97Å
69	V	93.1	Very high	89.8	Confident	0 Å²	0	17.9 Å²	17.9	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-66.3	-47.3	176.3	176.9	0	0	0	0	110.5	S65 P66 K67 N72 T73 I82 W83 A238	S65-V69 WeakPolarHBondContact O-CG2 3.43Å; S65-V69 PolarHBondContact O-N 3.31Å; P66-V69 PolarHBondContact O-N 3.32Å; K67-V69 PolarHBondContact O-N 3.08Å; V69-N72 PolarHBondContact O-N 3.46Å; V69-T73 HydrophobicContact CG1-CG2 4.37Å; V69-T73 WeakPolarHBondContact O-CB 3.38Å; V69-T73 WeakPolarHBondContact O-CG2 3.4Å; V69-T73 PolarHBondContact O-N 2.99Å; V69-T73 PolarHBondContact O-OG1 3.15Å; V69-I82 HydrophobicContact CG1-CB 4.3Å; V69-I82 HydrophobicContact CG1-CG2 4.18Å; V69-W83 HydrophobicContact CG2-CZ2 4.43Å; V69-A238 HydrophobicContact CG1-CB 4.46Å
70	L	93	Very high	90.5	Very high	4 Å²	4	19 Å²	19	2%	0.021	11%	0.106	C	C	.	.	H	α-helix	trans	-65.2	-42.8	-179.5	-175.1	61.6	0	0	0	112	P66 K67 N72 T73 G74 F289 A294 L297 L298	P66-L70 WeakPolarHBondContact O-CB 3.29Å; P66-L70 PolarHBondContact O-N 3.03Å; K67-L70 PolarHBondContact O-N 3.05Å; L70-N72 PolarHBondContact O-N 3.33Å; L70-T73 WeakPolarHBondContact CA-OG1 3.3Å; L70-T73 PolarHBondContact O-N 3.28Å; L70-T73 PolarHBondContact O-OG1 3.4Å; L70-G74 PolarHBondContact O-N 3.34Å; L70-F289 HydrophobicContact CD1-CE1 4.22Å; L70-F289 HydrophobicContact CD1-CZ 4.08Å; L70-F289 HydrophobicContact CD2-CE1 3.82Å; L70-F289 HydrophobicContact CD2-CZ 4.18Å; L70-A294 HydrophobicContact CD2-CB 3.99Å; L70-L297 HydrophobicContact CB-CD2 4.34Å; L70-L297 HydrophobicContact CD2-CB 4.17Å; L70-L297 HydrophobicContact CD2-CD1 4.23Å; L70-L297 HydrophobicContact CD2-CD2 3.81Å; L70-L297 HydrophobicContact CD2-CG 4.28Å; L70-L298 HydrophobicContact CB-CD2 4.19Å; L70-L298 HydrophobicContact CD2-CD2 4.23Å; L70-L298 HydrophobicContact CD2-CG 4.15Å; L70-L298 HydrophobicContact CG-CD2 4.19Å; L70-L298 HydrophobicContact CG-CG 4.47Å
71	Q	91.1	Very high	91.3	Very high	112 Å²	112	21.7 Å²	21.7	52%	0.523	12%	0.122	S	C	.	.	H	α-helix	trans	-59.2	-36.8	179.3	-174.3	175.6	-7.5	0	0	112.4	K67 L298	K67-Q71 VanDerWaalsContact O-CB 3.25Å; K67-Q71 WeakPolarHBondContact O-CB 3.38Å; K67-Q71 PolarHBondContact O-N 3.22Å; Q71-L298 HydrophobicContact CB-CD2 3.74Å; Q71-L298 HydrophobicContact CG-CD2 4.49Å
72	N	89.2	Confident	91.7	Very high	24 Å²	24	21.5 Å²	21.5	13%	0.128	12%	0.12	C	C	.	.	H	α-helix	trans	-90.6	-18.9	-177.2	-73.1	-68.4	0	0	0	113.7	G68 V69 L70 R234 L237 A238	G68-N72 WeakPolarHBondContact O-CB 3.23Å; G68-N72 PolarHBondContact O-N 2.65Å; G68-N72 PolarHBondContact O-ND2 2.97Å; V69-N72 PolarHBondContact O-N 3.46Å; L70-N72 PolarHBondContact O-N 3.33Å; N72-R234 WeakPolarHBondContact O-CB 3.49Å; N72-L237 HydrophobicContact CB-CB 4.2Å; N72-L237 WeakPolarHBondContact OD1-CB 3.44Å; N72-A238 HydrophobicContact CB-CB 3.79Å
73	T	90.9	Very high	92	Very high	6 Å²	6	21.5 Å²	21.5	4%	0.037	12%	0.12	C	C	.	.	H	α-helix	trans	-91.6	-30.5	174.6	47.6	0	0	0	0	113.6	V69 L70 S75 M78 S79 I82 A238	V69-T73 HydrophobicContact CG1-CG2 4.37Å; V69-T73 WeakPolarHBondContact O-CB 3.38Å; V69-T73 WeakPolarHBondContact O-CG2 3.4Å; V69-T73 PolarHBondContact O-N 2.99Å; V69-T73 PolarHBondContact O-OG1 3.15Å; L70-T73 WeakPolarHBondContact CA-OG1 3.3Å; L70-T73 PolarHBondContact O-N 3.28Å; L70-T73 PolarHBondContact O-OG1 3.4Å; T73-S75 PolarHBondContact O-N 3.1Å; T73-S75 VanDerWaalsContact O-N 3.13Å; T73-S75 PolarHBondContact OG1-O 2.9Å; T73-M78 HydrophobicContact CG2-CB 4.34Å; T73-M78 HydrophobicContact CG2-CG 3.97Å; T73-S79 WeakPolarHBondContact OG1-CB 3.44Å; T73-I82 HydrophobicContact CG2-CD1 3.18Å; T73-I82 HydrophobicContact CG2-CG1 4.21Å; T73-A238 HydrophobicContact CG2-CB 3.71Å
74	G	88.9	Confident	92.5	Very high	31 Å²	31	24.4 Å²	24.4	32%	0.32	14%	0.138	S	C	.	.			trans	70.6	-1.3	-178.9	0	0	0	0	0	114.9	L70 G227	L70-G74 PolarHBondContact O-N 3.34Å; G74-G227 WeakPolarHBondContact O-CA 3.23Å
75	S	91.3	Very high	93.1	Very high	4 Å²	4	25.2 Å²	25.2	3%	0.028	15%	0.145	C	C	.	.	S	Bend	trans	-144.8	140.9	-174.3	148.9	0	0	0	0	111	T73 G77 M78 S79 A224 F225	T73-S75 PolarHBondContact O-N 3.1Å; T73-S75 VanDerWaalsContact O-N 3.13Å; T73-S75 PolarHBondContact OG1-O 2.9Å; S75-G77 PolarHBondContact OG-N 3.05Å; S75-M78 PolarHBondContact OG-N 3.41Å; S75-S79 WeakPolarHBondContact O-CB 3.23Å; S75-S79 PolarHBondContact O-N 2.85Å; S75-A224 PolarHBondContact OG-O 3.42Å; S75-F225 WeakPolarHBondContact OG-CA 3.37Å
76	V	92.6	Very high	93.3	Very high	13 Å²	13	25.2 Å²	25.2	8%	0.079	15%	0.145	C	C	.	.	H	α-helix	trans	-62.4	-50.2	177.7	176	0	0	0	0	111.2	M78 S79 L80 F221 A224 F289 A294	V76-M78 PolarHBondContact O-N 3.44Å; V76-S79 WeakPolarHBondContact O-CB 3.42Å; V76-S79 PolarHBondContact O-N 2.75Å; V76-S79 PolarHBondContact O-OG 3.36Å; V76-L80 HydrophobicContact CG1-CD1 4.44Å; V76-L80 PolarHBondContact O-N 3.15Å; V76-L80 VanDerWaalsContact O-N 3.09Å; V76-F221 HydrophobicContact CG1-CD1 4.43Å; V76-F221 HydrophobicContact CG1-CE1 4.34Å; V76-A224 PolarHBondContact N-O 3.45Å; V76-F289 HydrophobicContact CB-CE1 4.49Å; V76-F289 HydrophobicContact CG1-CB 4.14Å; V76-F289 HydrophobicContact CG1-CD1 3.93Å; V76-F289 HydrophobicContact CG1-CD2 3.57Å; V76-F289 HydrophobicContact CG1-CE1 4.19Å; V76-F289 HydrophobicContact CG1-CE2 3.86Å; V76-F289 HydrophobicContact CG1-CG 3.61Å; V76-F289 HydrophobicContact CG1-CZ 4.16Å; V76-F289 HydrophobicContact CG2-CD1 3.9Å; V76-F289 HydrophobicContact CG2-CE1 3.85Å; V76-F289 HydrophobicContact CG2-CG 4.43Å; V76-F289 HydrophobicContact CG2-CZ 4.36Å; V76-A294 HydrophobicContact CG2-CB 4.38Å
77	G	93.2	Very high	93.5	Very high	6 Å²	6	25.1 Å²	25.1	6%	0.062	14%	0.144	C	C	.	.	H	α-helix	trans	-62.3	-40.9	-179.2	0	0	0	0	0	112.8	S75 L80 T81 A224 F225	S75-G77 PolarHBondContact OG-N 3.05Å; G77-L80 PolarHBondContact O-N 2.86Å; G77-T81 PolarHBondContact O-N 3.24Å; G77-T81 VanDerWaalsContact O-N 3.09Å; G77-T81 PolarHBondContact O-OG1 3.46Å; G77-A224 PolarHBondContact N-O 2.96Å; G77-F225 VanDerWaalsContact C-CE1 3.48Å
78	M	92.9	Very high	93.7	Very high	56 Å²	56	25.4 Å²	25.4	28%	0.276	15%	0.151	S	C	.	.	H	α-helix	trans	-68.6	-38.2	175.7	-166.6	62.8	-178.1	0	0	111.8	T73 S75 V76 L80 T81 I82 L235	T73-M78 HydrophobicContact CG2-CB 4.34Å; T73-M78 HydrophobicContact CG2-CG 3.97Å; S75-M78 PolarHBondContact OG-N 3.41Å; V76-M78 PolarHBondContact O-N 3.44Å; M78-L80 PolarHBondContact O-N 2.81Å; M78-T81 WeakPolarHBondContact O-CB 3.28Å; M78-T81 PolarHBondContact O-N 3.48Å; M78-I82 WeakPolarHBondContact O-CG1 3.28Å; M78-I82 PolarHBondContact O-N 2.8Å; M78-L235 HydrophobicContact CE-CD1 3.4Å; M78-L235 HydrophobicContact CE-CD2 4.01Å; M78-L235 HydrophobicContact CE-CG 4.37Å; M78-L235 HydrophobicContact CG-CD1 4.45Å
79	S	94.6	Very high	94.1	Very high	2 Å²	2	26.1 Å²	26.1	1%	0.014	15%	0.153	C	C	.	.	H	α-helix	trans	-58.9	-45.2	175.5	81	0	0	0	0	112.2	T73 S75 V76 I82 W83 F289	T73-S79 WeakPolarHBondContact OG1-CB 3.44Å; S75-S79 WeakPolarHBondContact O-CB 3.23Å; S75-S79 PolarHBondContact O-N 2.85Å; V76-S79 WeakPolarHBondContact O-CB 3.42Å; V76-S79 PolarHBondContact O-N 2.75Å; V76-S79 PolarHBondContact O-OG 3.36Å; S79-I82 PolarHBondContact O-N 3.34Å; S79-W83 PolarHBondContact O-N 3.3Å; S79-W83 VanDerWaalsContact O-N 3.1Å; S79-F289 WeakPolarHBondContact OG-CE2 3.23Å
80	L	95.9	Very high	94.2	Very high	26 Å²	26	26.1 Å²	26.1	14%	0.136	15%	0.153	C	C	.	.	H	α-helix	trans	-65.4	-40	177.8	-67.8	175.4	0	0	0	111.8	V76 G77 M78 I82 W83 T84 F221 N285 V286 F289	V76-L80 HydrophobicContact CG1-CD1 4.44Å; V76-L80 PolarHBondContact O-N 3.15Å; V76-L80 VanDerWaalsContact O-N 3.09Å; G77-L80 PolarHBondContact O-N 2.86Å; M78-L80 PolarHBondContact O-N 2.81Å; L80-I82 VanDerWaalsContact C-N 3.3Å; L80-I82 PolarHBondContact O-N 2.83Å; L80-W83 PolarHBondContact O-N 2.87Å; L80-T84 PolarHBondContact O-N 3.49Å; L80-T84 PolarHBondContact O-OG1 2.95Å; L80-F221 HydrophobicContact CD1-CE1 3.99Å; L80-N285 HydrophobicContact CD2-CB 3.61Å; L80-V286 HydrophobicContact CD1-CG2 4.11Å; L80-V286 HydrophobicContact CD2-CG2 4.01Å; L80-F289 HydrophobicContact CD2-CD2 4.28Å; L80-F289 HydrophobicContact CD2-CE2 4.22Å; L80-F289 HydrophobicContact CG-CD2 4.49Å; L80-F289 HydrophobicContact CG-CE2 4.38Å
81	T	95.9	Very high	94.4	Very high	59 Å²	59	28.5 Å²	28.5	36%	0.362	17%	0.166	S	C	.	.	H	α-helix	trans	-58	-44.2	174.7	-57.1	0	0	0	0	110.8	G77 M78 W83 T84 V85	G77-T81 PolarHBondContact O-N 3.24Å; G77-T81 VanDerWaalsContact O-N 3.09Å; G77-T81 PolarHBondContact O-OG1 3.46Å; M78-T81 WeakPolarHBondContact O-CB 3.28Å; M78-T81 PolarHBondContact O-N 3.48Å; T81-W83 PolarHBondContact O-N 3.28Å; T81-T84 PolarHBondContact O-N 3.21Å; T81-V85 HydrophobicContact CG2-CG2 4.3Å; T81-V85 VanDerWaalsContact O-CG2 3.3Å; T81-V85 WeakPolarHBondContact O-CG2 3.17Å; T81-V85 PolarHBondContact O-N 3.41Å
82	I	95.5	Very high	94.7	Very high	2 Å²	2	24.9 Å²	24.9	1%	0.01	15%	0.148	C	C	.	.	H	α-helix	trans	-64.6	-40.8	177.6	-69.9	-177.7	0	0	0	112.2	V69 T73 M78 S79 L80 T84 V85 C86 L235 A238 F239	V69-I82 HydrophobicContact CG1-CB 4.3Å; V69-I82 HydrophobicContact CG1-CG2 4.18Å; T73-I82 HydrophobicContact CG2-CD1 3.18Å; T73-I82 HydrophobicContact CG2-CG1 4.21Å; M78-I82 WeakPolarHBondContact O-CG1 3.28Å; M78-I82 PolarHBondContact O-N 2.8Å; S79-I82 PolarHBondContact O-N 3.34Å; L80-I82 VanDerWaalsContact C-N 3.3Å; L80-I82 PolarHBondContact O-N 2.83Å; I82-T84 VanDerWaalsContact C-N 3.31Å; I82-T84 PolarHBondContact O-N 3.1Å; I82-V85 PolarHBondContact O-N 2.82Å; I82-C86 VanDerWaalsContact O-CB 3.26Å; I82-C86 WeakPolarHBondContact O-CB 3.44Å; I82-C86 PolarHBondContact O-N 3.27Å; I82-C86 PolarHBondContact O-SG 3.48Å; I82-L235 HydrophobicContact CD1-CD1 3.35Å; I82-L235 HydrophobicContact CD1-CG 4.44Å; I82-L235 HydrophobicContact CG1-CD1 4.18Å; I82-A238 HydrophobicContact CD1-CB 3.35Å; I82-F239 HydrophobicContact CG1-CZ 4.49Å; I82-F239 HydrophobicContact CG2-CD1 4.41Å
83	W	97.2	Very high	95	Very high	1 Å²	1	23.7 Å²	23.7	0%	0.004	14%	0.142	C	C	.	.	H	α-helix	trans	-57.3	-46.5	174.3	-81.8	104.1	0	0	0	111.4	I62 P66 V69 S79 L80 T81 G87 A245 Y246 Y281 V282 N285	I62-W83 HydrophobicContact CD1-CH2 3.5Å; I62-W83 HydrophobicContact CD1-CZ2 4.07Å; I62-W83 HydrophobicContact CD1-CZ3 3.77Å; P66-W83 HydrophobicContact CG-CZ2 4.02Å; V69-W83 HydrophobicContact CG2-CZ2 4.43Å; S79-W83 PolarHBondContact O-N 3.3Å; S79-W83 VanDerWaalsContact O-N 3.1Å; L80-W83 PolarHBondContact O-N 2.87Å; T81-W83 PolarHBondContact O-N 3.28Å; W83-G87 PolarHBondContact O-N 3.47Å; W83-A245 HydrophobicContact CH2-CB 3.54Å; W83-A245 HydrophobicContact CZ3-CB 3.55Å; W83-Y246 HydrophobicContact CE3-CD2 4.48Å; W83-Y246 AromaticContact CE3-CE2 3.6Å; W83-Y246 HydrophobicContact CE3-CE2 3.6Å; W83-Y246 HydrophobicContact CZ3-CE2 4.01Å; W83-Y246 WeakPolarHBondContact O-CE2 3.41Å; W83-Y246 PolarHBondContact O-OH 3.35Å; W83-Y246 VanDerWaalsContact O-OH 3.13Å; W83-Y281 AromaticContact CE3-CD2 3.89Å; W83-Y281 HydrophobicContact CE3-CD2 3.89Å; W83-Y281 HydrophobicContact CE3-CG 4.29Å; W83-Y281 HydrophobicContact CH2-CD2 4.47Å; W83-Y281 AromaticContact CZ3-CD2 3.41Å; W83-Y281 HydrophobicContact CZ3-CD2 3.41Å; W83-Y281 VanDerWaalsContact CZ3-CD2 3.41Å; W83-Y281 HydrophobicContact CZ3-CE2 4.04Å; W83-Y281 AromaticContact CZ3-CG 3.96Å; W83-Y281 HydrophobicContact CZ3-CG 3.96Å; W83-V282 HydrophobicContact CB-CG2 4.19Å; W83-N285 VanDerWaalsContact NE1-CG 3.32Å; W83-N285 PolarHBondContact NE1-ND2 2.85Å; W83-N285 PolarHBondContact NE1-OD1 3.12Å; W83-N285 VanDerWaalsContact NE1-OD1 3.1Å
84	T	97.4	Very high	95.2	Very high	64 Å²	64	23.4 Å²	23.4	39%	0.393	14%	0.14	S	C	.	.	H	α-helix	trans	-62.6	-48.5	177	-54.1	0	0	0	0	112.2	L80 T81 I82 C86 G87 V88	L80-T84 PolarHBondContact O-N 3.49Å; L80-T84 PolarHBondContact O-OG1 2.95Å; T81-T84 PolarHBondContact O-N 3.21Å; I82-T84 VanDerWaalsContact C-N 3.31Å; I82-T84 PolarHBondContact O-N 3.1Å; T84-C86 PolarHBondContact O-N 3.23Å; T84-G87 PolarHBondContact O-N 3.5Å; T84-V88 WeakPolarHBondContact O-CG2 3.26Å; T84-V88 PolarHBondContact O-N 3.49Å
85	V	96.8	Very high	95.6	Very high	54 Å²	54	23 Å²	23	33%	0.327	13%	0.131	S	C	.	.	H	α-helix	trans	-63.9	-42.8	-179.4	178.4	0	0	0	0	110.9	T81 I82 G87 V88 L89 F239	T81-V85 HydrophobicContact CG2-CG2 4.3Å; T81-V85 VanDerWaalsContact O-CG2 3.3Å; T81-V85 WeakPolarHBondContact O-CG2 3.17Å; T81-V85 PolarHBondContact O-N 3.41Å; I82-V85 PolarHBondContact O-N 2.82Å; V85-G87 VanDerWaalsContact C-N 3.28Å; V85-G87 PolarHBondContact O-N 2.82Å; V85-V88 PolarHBondContact O-N 2.79Å; V85-L89 HydrophobicContact CG1-CD1 3.84Å; V85-L89 HydrophobicContact CG1-CG 4.14Å; V85-L89 WeakPolarHBondContact O-CB 3.37Å; V85-L89 VanDerWaalsContact O-CG 3.31Å; V85-L89 WeakPolarHBondContact O-CG 3.38Å; V85-L89 PolarHBondContact O-N 2.99Å; V85-F239 HydrophobicContact CB-CE1 4.07Å; V85-F239 HydrophobicContact CB-CZ 4.45Å; V85-F239 HydrophobicContact CG1-CE1 3.61Å; V85-F239 HydrophobicContact CG1-CZ 4Å
86	C	96.4	Very high	95.9	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-59.2	-38.9	174.9	-72.5	0	0	0	0	112.2	I82 T84 S90 M243 Y246	I82-C86 VanDerWaalsContact O-CB 3.26Å; I82-C86 WeakPolarHBondContact O-CB 3.44Å; I82-C86 PolarHBondContact O-N 3.27Å; I82-C86 PolarHBondContact O-SG 3.48Å; T84-C86 PolarHBondContact O-N 3.23Å; C86-S90 WeakPolarHBondContact O-CB 3.27Å; C86-S90 PolarHBondContact O-N 2.97Å; C86-S90 PolarHBondContact O-OG 3.06Å; C86-M243 HydrophobicContact CB-CG 4.49Å; C86-M243 HydrophobicContact CB-SD 3.88Å; C86-Y246 HydrophobicContact CB-CD2 3.69Å; C86-Y246 HydrophobicContact CB-CE2 3.77Å
87	G	96.8	Very high	96	Very high	1 Å²	1	22.2 Å²	22.2	1%	0.01	13%	0.126	C	C	.	.	H	α-helix	trans	-62.7	-45.3	174.3	0	0	0	0	0	112.7	W83 T84 V85 S90 L91	W83-G87 PolarHBondContact O-N 3.47Å; T84-G87 PolarHBondContact O-N 3.5Å; V85-G87 VanDerWaalsContact C-N 3.28Å; V85-G87 PolarHBondContact O-N 2.82Å; G87-S90 PolarHBondContact O-N 3.33Å; G87-L91 PolarHBondContact O-N 3.18Å
88	V	97	Very high	96.1	Very high	64 Å²	64	21.9 Å²	21.9	39%	0.388	12%	0.123	S	C	.	.	H	α-helix	trans	-64.5	-46.4	176.9	174	0	0	0	0	111.7	T84 V85 S90 L91 F92	T84-V88 WeakPolarHBondContact O-CG2 3.26Å; T84-V88 PolarHBondContact O-N 3.49Å; V85-V88 PolarHBondContact O-N 2.79Å; V88-S90 VanDerWaalsContact C-N 3.31Å; V88-S90 PolarHBondContact O-N 3.13Å; V88-L91 WeakPolarHBondContact O-CB 3.48Å; V88-L91 PolarHBondContact O-N 3.35Å; V88-F92 HydrophobicContact CG1-CE1 4.15Å; V88-F92 HydrophobicContact CG1-CE2 3.93Å; V88-F92 HydrophobicContact CG1-CZ 3.72Å; V88-F92 PolarHBondContact O-N 3.17Å
89	L	96.4	Very high	96.2	Very high	20 Å²	20	19.3 Å²	19.3	11%	0.105	11%	0.11	C	C	.	.	H	α-helix	trans	-62.3	-40.5	177.2	-67.7	175.4	0	0	0	111.2	V85 L91 F92 G93 F239 M243 L430 F431 T434	V85-L89 HydrophobicContact CG1-CD1 3.84Å; V85-L89 HydrophobicContact CG1-CG 4.14Å; V85-L89 WeakPolarHBondContact O-CB 3.37Å; V85-L89 VanDerWaalsContact O-CG 3.31Å; V85-L89 WeakPolarHBondContact O-CG 3.38Å; V85-L89 PolarHBondContact O-N 2.99Å; L89-L91 VanDerWaalsContact C-N 3.33Å; L89-L91 PolarHBondContact O-N 3.44Å; L89-F92 HydrophobicContact CD2-CD2 4.41Å; L89-F92 WeakPolarHBondContact O-CB 3.46Å; L89-F92 PolarHBondContact O-N 2.89Å; L89-G93 PolarHBondContact O-N 2.95Å; L89-G93 VanDerWaalsContact O-N 3.08Å; L89-F239 HydrophobicContact CD1-CE1 4.24Å; L89-M243 HydrophobicContact CB-CE 4.27Å; L89-M243 HydrophobicContact CB-SD 4.12Å; L89-L430 HydrophobicContact CD2-CG 4.38Å; L89-F431 WeakPolarHBondContact O-CD2 3.28Å; L89-T434 HydrophobicContact CB-CG2 4.49Å; L89-T434 HydrophobicContact CD1-CG2 3.86Å
90	S	96	Very high	96.2	Very high	0 Å²	0	19.2 Å²	19.2	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-65.5	-36.4	175.3	-63	0	0	0	0	112.3	C86 G87 V88 F92 G93 A94 Y246 M274	C86-S90 WeakPolarHBondContact O-CB 3.27Å; C86-S90 PolarHBondContact O-N 2.97Å; C86-S90 PolarHBondContact O-OG 3.06Å; G87-S90 PolarHBondContact O-N 3.33Å; V88-S90 VanDerWaalsContact C-N 3.31Å; V88-S90 PolarHBondContact O-N 3.13Å; S90-F92 VanDerWaalsContact C-N 3.33Å; S90-G93 PolarHBondContact O-N 3.02Å; S90-A94 WeakPolarHBondContact O-CB 3.42Å; S90-A94 PolarHBondContact O-N 3.34Å; S90-Y246 WeakPolarHBondContact OG-CB 3.49Å; S90-M274 VanDerWaalsContact CB-CE 3.49Å
91	L	96.1	Very high	96	Very high	53 Å²	53	18 Å²	18	28%	0.277	10%	0.103	S	C	.	.	H	α-helix	trans	-61.8	-41.5	172	177	64	0	0	0	110.9	G87 V88 L89 G93 A94 L95 M274	G87-L91 PolarHBondContact O-N 3.18Å; V88-L91 WeakPolarHBondContact O-CB 3.48Å; V88-L91 PolarHBondContact O-N 3.35Å; L89-L91 VanDerWaalsContact C-N 3.33Å; L89-L91 PolarHBondContact O-N 3.44Å; L91-G93 PolarHBondContact O-N 3.35Å; L91-A94 PolarHBondContact O-N 2.92Å; L91-L95 HydrophobicContact CD1-CD1 4.09Å; L91-L95 HydrophobicContact CD1-CD2 4.36Å; L91-L95 HydrophobicContact CD1-CG 3.92Å; L91-L95 HydrophobicContact CG-CD1 3.88Å; L91-L95 HydrophobicContact CG-CG 4.18Å; L91-L95 WeakPolarHBondContact O-CB 3.41Å; L91-L95 WeakPolarHBondContact O-CG 3.41Å; L91-L95 PolarHBondContact O-N 3.46Å; L91-M274 HydrophobicContact CD1-CB 3.85Å; L91-M274 HydrophobicContact CD1-CG 4.17Å
92	F	97.3	Very high	95.9	Very high	36 Å²	36	15.2 Å²	15.2	16%	0.158	9%	0.086	C	C	.	.	H	α-helix	trans	-62	-41.3	175.9	-67.2	-13.9	0	0	0	112.9	V88 L89 S90 S96 F426 I427 L430 F431	V88-F92 HydrophobicContact CG1-CE1 4.15Å; V88-F92 HydrophobicContact CG1-CE2 3.93Å; V88-F92 HydrophobicContact CG1-CZ 3.72Å; V88-F92 PolarHBondContact O-N 3.17Å; L89-F92 HydrophobicContact CD2-CD2 4.41Å; L89-F92 WeakPolarHBondContact O-CB 3.46Å; L89-F92 PolarHBondContact O-N 2.89Å; S90-F92 VanDerWaalsContact C-N 3.33Å; F92-S96 WeakPolarHBondContact O-CB 3.45Å; F92-S96 PolarHBondContact O-N 2.62Å; F92-S96 PolarHBondContact O-OG 3.33Å; F92-F426 HydrophobicContact CZ-CE2 4.43Å; F92-I427 HydrophobicContact CB-CG2 3.67Å; F92-I427 HydrophobicContact CD1-CD1 4.36Å; F92-I427 HydrophobicContact CD1-CG1 4.24Å; F92-I427 HydrophobicContact CD1-CG2 3.94Å; F92-I427 HydrophobicContact CE1-CD1 4.5Å; F92-I427 HydrophobicContact CE1-CG1 4.41Å; F92-I427 HydrophobicContact CG-CG2 3.95Å; F92-I427 WeakPolarHBondContact O-CG2 3.45Å; F92-L430 HydrophobicContact CD2-CD2 3.86Å; F92-L430 HydrophobicContact CD2-CG 4.4Å; F92-L430 HydrophobicContact CE2-CD2 3.55Å; F92-F431 HydrophobicContact CB-CB 4.09Å
93	G	96.2	Very high	95.7	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-60.3	-46.9	171.3	0	0	0	0	0	112.2	L89 S90 L91 L95 S96 Y97 W249 F431	L89-G93 PolarHBondContact O-N 2.95Å; L89-G93 VanDerWaalsContact O-N 3.08Å; S90-G93 PolarHBondContact O-N 3.02Å; L91-G93 PolarHBondContact O-N 3.35Å; G93-L95 PolarHBondContact O-N 2.71Å; G93-S96 WeakPolarHBondContact O-CB 3.46Å; G93-S96 PolarHBondContact O-N 3.05Å; G93-Y97 WeakPolarHBondContact O-CD2 3.26Å; G93-Y97 PolarHBondContact O-N 3.43Å; G93-W249 VanDerWaalsContact C-CZ3 3.44Å; G93-W249 WeakPolarHBondContact O-CH2 3.35Å; G93-W249 WeakPolarHBondContact O-CZ3 3.45Å; G93-F431 VanDerWaalsContact CA-CD1 3.44Å; G93-F431 VanDerWaalsContact CA-CE1 3.48Å; G93-F431 VanDerWaalsContact CA-CG 3.46Å
94	A	95.8	Very high	95.4	Very high	0 Å²	0	17 Å²	17	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-65	-41.5	-178.6	0	0	0	0	0	113.1	S90 L91 S96 Y97 A98 W249 I270 M274	S90-A94 WeakPolarHBondContact O-CB 3.42Å; S90-A94 PolarHBondContact O-N 3.34Å; L91-A94 PolarHBondContact O-N 2.92Å; A94-S96 VanDerWaalsContact C-N 3.33Å; A94-S96 PolarHBondContact O-N 3.23Å; A94-Y97 CarbonylContact O-C 3.59Å; A94-Y97 PolarHBondContact O-N 3.38Å; A94-A98 PolarHBondContact O-N 3.06Å; A94-W249 HydrophobicContact CB-CB 3.83Å; A94-W249 HydrophobicContact CB-CD2 3.64Å; A94-W249 HydrophobicContact CB-CE3 3.57Å; A94-W249 HydrophobicContact CB-CG 3.77Å; A94-W249 HydrophobicContact CB-CZ3 4.34Å; A94-I270 HydrophobicContact CB-CG2 3.35Å; A94-M274 HydrophobicContact CB-CG 4.13Å
95	L	96.5	Very high	94.9	Very high	22 Å²	22	18.8 Å²	18.8	12%	0.115	10%	0.099	C	C	.	.	H	α-helix	trans	-64	-38.6	174.2	-70.1	174.4	0	0	0	111.8	L91 G93 Y97 A98 E99 F421 V423 I427	L91-L95 HydrophobicContact CD1-CD1 4.09Å; L91-L95 HydrophobicContact CD1-CD2 4.36Å; L91-L95 HydrophobicContact CD1-CG 3.92Å; L91-L95 HydrophobicContact CG-CD1 3.88Å; L91-L95 HydrophobicContact CG-CG 4.18Å; L91-L95 WeakPolarHBondContact O-CB 3.41Å; L91-L95 WeakPolarHBondContact O-CG 3.41Å; L91-L95 PolarHBondContact O-N 3.46Å; G93-L95 PolarHBondContact O-N 2.71Å; L95-Y97 VanDerWaalsContact C-N 3.34Å; L95-Y97 PolarHBondContact O-N 3.46Å; L95-A98 WeakPolarHBondContact O-CB 3.47Å; L95-A98 PolarHBondContact O-N 2.92Å; L95-E99 PolarHBondContact O-N 3.41Å; L95-E99 VanDerWaalsContact O-N 3.1Å; L95-F421 HydrophobicContact CD2-CE1 4.29Å; L95-F421 HydrophobicContact CD2-CZ 3.89Å; L95-V423 HydrophobicContact CB-CG1 3.91Å; L95-I427 HydrophobicContact CB-CG2 4.35Å; L95-I427 HydrophobicContact CD1-CD1 4.19Å
96	S	96.8	Very high	94.3	Very high	0 Å²	0	20.1 Å²	20.1	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-63.5	-40.7	174.7	-56.2	0	0	0	0	111.6	F92 G93 A94 E99 L100 P428	F92-S96 WeakPolarHBondContact O-CB 3.45Å; F92-S96 PolarHBondContact O-N 2.62Å; F92-S96 PolarHBondContact O-OG 3.33Å; G93-S96 WeakPolarHBondContact O-CB 3.46Å; G93-S96 PolarHBondContact O-N 3.05Å; A94-S96 VanDerWaalsContact C-N 3.33Å; A94-S96 PolarHBondContact O-N 3.23Å; S96-E99 PolarHBondContact O-N 2.93Å; S96-L100 PolarHBondContact O-N 3.19Å; S96-L100 VanDerWaalsContact O-N 3.1Å; S96-P428 WeakPolarHBondContact OG-CA 3.44Å
97	Y	95.1	Very high	93.7	Very high	0 Å²	0	20.3 Å²	20.3	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-71.5	-30.5	173.6	-90.4	-118.7	0	0	0	113.2	G93 A94 L95 E99 L100 G101 H110 Y113 W249 F250 N253 I400 A403 V404	G93-Y97 WeakPolarHBondContact O-CD2 3.26Å; G93-Y97 PolarHBondContact O-N 3.43Å; A94-Y97 CarbonylContact O-C 3.59Å; A94-Y97 PolarHBondContact O-N 3.38Å; L95-Y97 VanDerWaalsContact C-N 3.34Å; L95-Y97 PolarHBondContact O-N 3.46Å; Y97-E99 VanDerWaalsContact C-N 3.3Å; Y97-E99 PolarHBondContact O-N 2.93Å; Y97-L100 PolarHBondContact O-N 2.91Å; Y97-G101 PolarHBondContact O-N 2.88Å; Y97-H110 HydrophobicContact CE1-CB 4.42Å; Y97-Y113 HydrophobicContact CD1-CD2 4.35Å; Y97-Y113 AromaticContact CD1-CE2 3.74Å; Y97-Y113 HydrophobicContact CD1-CE2 3.74Å; Y97-Y113 HydrophobicContact CE1-CD2 4.2Å; Y97-Y113 AromaticContact CE1-CE2 3.98Å; Y97-Y113 HydrophobicContact CE1-CE2 3.98Å; Y97-Y113 HydrophobicContact CG-CE2 4.48Å; Y97-W249 HydrophobicContact CD1-CZ3 4.04Å; Y97-W249 AromaticContact CD2-CH2 3.53Å; Y97-W249 HydrophobicContact CD2-CH2 3.53Å; Y97-W249 AromaticContact CD2-CZ3 3.36Å; Y97-W249 HydrophobicContact CD2-CZ3 3.36Å; Y97-W249 HydrophobicContact CE1-CZ3 4.49Å; Y97-W249 AromaticContact CE2-CH2 3.66Å; Y97-W249 HydrophobicContact CE2-CH2 3.66Å; Y97-W249 AromaticContact CE2-CZ3 3.87Å; Y97-W249 HydrophobicContact CE2-CZ3 3.87Å; Y97-W249 HydrophobicContact CG-CE3 4.48Å; Y97-W249 HydrophobicContact CG-CH2 4.1Å; Y97-W249 AromaticContact CG-CZ3 3.45Å; Y97-W249 HydrophobicContact CG-CZ3 3.45Å; Y97-W249 VanDerWaalsContact CG-CZ3 3.45Å; Y97-F250 HydrophobicContact CD1-CB 3.82Å; Y97-F250 HydrophobicContact CE1-CB 3.83Å; Y97-F250 HydrophobicContact CG-CB 4.5Å; Y97-N253 HydrophobicContact CD1-CB 4.31Å; Y97-N253 PolarHBondContact O-ND2 3.15Å; Y97-I400 HydrophobicContact CE2-CG2 4.22Å; Y97-A403 HydrophobicContact CE2-CB 4.49Å; Y97-V404 HydrophobicContact CD2-CG2 3.97Å; Y97-V404 HydrophobicContact CE2-CG2 3.66Å
98	A	94.9	Very high	93.1	Very high	0 Å²	0	20.2 Å²	20.2	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-61.6	-42.1	172.8	0	0	0	0	0	110.6	A94 L95 G101 T102 I266 P267 I270 F421	A94-A98 PolarHBondContact O-N 3.06Å; L95-A98 WeakPolarHBondContact O-CB 3.47Å; L95-A98 PolarHBondContact O-N 2.92Å; A98-G101 PolarHBondContact O-N 3.21Å; A98-T102 WeakPolarHBondContact O-CB 3.38Å; A98-T102 VanDerWaalsContact O-CG2 3.25Å; A98-T102 WeakPolarHBondContact O-CG2 3.33Å; A98-T102 PolarHBondContact O-N 3.48Å; A98-T102 PolarHBondContact O-OG1 3.09Å; A98-I266 HydrophobicContact CB-CG2 4.32Å; A98-P267 HydrophobicContact CB-CB 4.41Å; A98-P267 HydrophobicContact CB-CG 4.35Å; A98-I270 HydrophobicContact CB-CD1 3.89Å; A98-F421 HydrophobicContact CB-CD1 3.87Å; A98-F421 HydrophobicContact CB-CE1 3.77Å
99	E	95.8	Very high	92.8	Very high	1 Å²	1	17.2 Å²	17.2	1%	0.005	8%	0.083	C	C	.	.	H	α-helix	trans	-62.5	-47.8	172.9	176	171.7	152.9	0	0	111.8	L95 S96 Y97 G101 T102 S103 L407 R411 R419 F421 K422 V423	L95-E99 PolarHBondContact O-N 3.41Å; L95-E99 VanDerWaalsContact O-N 3.1Å; S96-E99 PolarHBondContact O-N 2.93Å; Y97-E99 VanDerWaalsContact C-N 3.3Å; Y97-E99 PolarHBondContact O-N 2.93Å; E99-G101 PolarHBondContact O-N 2.96Å; E99-T102 PolarHBondContact O-N 2.85Å; E99-T102 PolarHBondContact O-OG1 3.31Å; E99-T102 VanDerWaalsContact O-OG1 3.09Å; E99-S103 VanDerWaalsContact O-CB 3.32Å; E99-S103 WeakPolarHBondContact O-CB 3.21Å; E99-S103 PolarHBondContact O-N 3.05Å; E99-S103 PolarHBondContact O-OG 2.83Å; E99-L407 HydrophobicContact CB-CD1 4.42Å; E99-L407 HydrophobicContact CB-CD2 4.28Å; E99-L407 HydrophobicContact CG-CD1 3.74Å; E99-L407 HydrophobicContact CG-CD2 4.3Å; E99-L407 VanDerWaalsContact OE1-CD1 3.29Å; E99-L407 WeakPolarHBondContact OE1-CD1 3.49Å; E99-R411 IonicContact OE1-CZ 2.97Å; E99-R411 IonicContact OE1-NE 2.77Å; E99-R411 PolarHBondContact OE1-NE 3.2Å; E99-R411 IonicContact OE1-NH2 2.65Å; E99-R411 PolarHBondContact OE1-NH2 2.94Å; E99-R411 IonicContact OE2-CZ 3.76Å; E99-R411 IonicContact OE2-NE 3.92Å; E99-R411 IonicContact OE2-NH2 2.78Å; E99-R411 PolarHBondContact OE2-NH2 3.44Å; E99-R419 IonicContact OE1-NE 3.77Å; E99-F421 HydrophobicContact CB-CD1 4.24Å; E99-F421 WeakPolarHBondContact CG-O 3.34Å; E99-K422 WeakPolarHBondContact OE2-CA 3.42Å; E99-V423 HydrophobicContact CB-CG2 4.48Å; E99-V423 VanDerWaalsContact OE2-CG2 3.24Å; E99-V423 WeakPolarHBondContact OE2-CG2 3.26Å; E99-V423 PolarHBondContact OE2-N 2.97Å
100	L	94.9	Very high	92.6	Very high	1 Å²	1	16.3 Å²	16.3	1%	0.005	8%	0.078	C	C	.	.	H	α-helix	trans	-60.2	-44.2	177.3	-76.4	169.8	0	0	0	112.3	S96 Y97 S103 I104 Y113 L407 L410	S96-L100 PolarHBondContact O-N 3.19Å; S96-L100 VanDerWaalsContact O-N 3.1Å; Y97-L100 PolarHBondContact O-N 2.91Å; L100-S103 PolarHBondContact O-N 3.17Å; L100-I104 HydrophobicContact CD2-CD1 4.39Å; L100-I104 WeakPolarHBondContact O-CB 3.42Å; L100-I104 PolarHBondContact O-N 3.39Å; L100-Y113 HydrophobicContact CB-CD1 4.2Å; L100-Y113 HydrophobicContact CB-CD2 3.92Å; L100-Y113 HydrophobicContact CB-CE1 4.02Å; L100-Y113 HydrophobicContact CB-CE2 3.71Å; L100-Y113 HydrophobicContact CB-CG 4.18Å; L100-Y113 HydrophobicContact CD1-CD2 3.68Å; L100-Y113 HydrophobicContact CD1-CE2 4.16Å; L100-Y113 HydrophobicContact CD1-CG 4.1Å; L100-Y113 HydrophobicContact CD2-CG 4.43Å; L100-Y113 HydrophobicContact CG-CD2 4.33Å; L100-Y113 HydrophobicContact CG-CG 4.48Å; L100-L407 HydrophobicContact CD1-CB 4.13Å; L100-L407 HydrophobicContact CD2-CB 3.86Å; L100-L407 HydrophobicContact CD2-CD1 3.53Å; L100-L407 HydrophobicContact CD2-CG 4.26Å; L100-L407 HydrophobicContact CG-CB 3.97Å; L100-L407 HydrophobicContact CG-CD1 3.73Å; L100-L407 HydrophobicContact CG-CD2 4.42Å; L100-L407 HydrophobicContact CG-CG 4.24Å; L100-L410 HydrophobicContact CD2-CD1 4.24Å
101	G	91.8	Very high	92.4	Very high	0 Å²	0	16.3 Å²	16.3	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-73	-26.1	-178	0	0	0	0	0	114.7	Y97 A98 E99 Y113	Y97-G101 PolarHBondContact O-N 2.88Å; A98-G101 PolarHBondContact O-N 3.21Å; E99-G101 PolarHBondContact O-N 2.96Å; G101-Y113 WeakPolarHBondContact CA-OH 3.48Å; G101-Y113 PolarHBondContact N-OH 3.38Å
102	T	92.9	Very high	92.3	Very high	1 Å²	1	13.9 Å²	13.9	1%	0.006	7%	0.066	C	C	.	.	H	α-helix	trans	-82.6	-26.8	172.8	54.5	0	0	0	0	112.4	A98 E99 K105 P267 F421	A98-T102 WeakPolarHBondContact O-CB 3.38Å; A98-T102 VanDerWaalsContact O-CG2 3.25Å; A98-T102 WeakPolarHBondContact O-CG2 3.33Å; A98-T102 PolarHBondContact O-N 3.48Å; A98-T102 PolarHBondContact O-OG1 3.09Å; E99-T102 PolarHBondContact O-N 2.85Å; E99-T102 PolarHBondContact O-OG1 3.31Å; E99-T102 VanDerWaalsContact O-OG1 3.09Å; T102-K105 WeakPolarHBondContact O-CE 3.29Å; T102-P267 HydrophobicContact CG2-CG 3.98Å; T102-F421 HydrophobicContact CG2-CB 4.17Å
103	S	92.6	Very high	92.2	Very high	23 Å²	23	12.2 Å²	12.2	16%	0.161	6%	0.058	C	C	.	.	H	α-helix	trans	-83.3	-43.4	176.9	-52.1	0	0	0	0	112.6	E99 L100	E99-S103 VanDerWaalsContact O-CB 3.32Å; E99-S103 WeakPolarHBondContact O-CB 3.21Å; E99-S103 PolarHBondContact O-N 3.05Å; E99-S103 PolarHBondContact O-OG 2.83Å; L100-S103 PolarHBondContact O-N 3.17Å
104	I	91.1	Very high	92.2	Very high	18 Å²	18	12.2 Å²	12.2	9%	0.092	6%	0.058	C	C	.	.	S	Bend	trans	-110.8	90.5	-179	-55.5	171.2	0	0	0	108	L100 K106 T112 Y113 E116 L410	L100-I104 HydrophobicContact CD2-CD1 4.39Å; L100-I104 WeakPolarHBondContact O-CB 3.42Å; L100-I104 PolarHBondContact O-N 3.39Å; I104-K106 HydrophobicContact CG2-CB 4.34Å; I104-K106 PolarHBondContact O-N 2.94Å; I104-T112 HydrophobicContact CG2-CG2 4.06Å; I104-Y113 HydrophobicContact CB-CD1 4.14Å; I104-Y113 HydrophobicContact CB-CE1 4.01Å; I104-Y113 HydrophobicContact CD1-CD1 3.89Å; I104-Y113 HydrophobicContact CG2-CD1 4.27Å; I104-Y113 HydrophobicContact CG2-CE1 4.31Å; I104-E116 HydrophobicContact CD1-CB 4.19Å; I104-E116 HydrophobicContact CD1-CG 4.34Å; I104-E116 HydrophobicContact CG2-CG 4.09Å; I104-L410 HydrophobicContact CD1-CD1 4.19Å
105	K	85.4	Confident	92.2	Very high	100 Å²	100	13.5 Å²	13.5	44%	0.435	7%	0.065	S	C	.	.			trans	-80.6	32.4	-173.6	-59.1	177.1	-176.8	171.5	0	114.1	T102 E263	T102-K105 WeakPolarHBondContact O-CE 3.29Å; K105-E263 WeakPolarHBondContact CE-OE1 3.34Å; K105-E263 IonicContact NZ-OE1 3.54Å; K105-E263 PolarHBondContact NZ-OE1 3.21Å
106	K	84.8	Confident	92	Very high	83 Å²	83	16.7 Å²	16.7	36%	0.361	8%	0.079	S	C	.	.			trans	-101.1	143.2	175.8	-73.9	-179.3	-178.3	-178.4	0	109	I104 T112 E116	I104-K106 HydrophobicContact CG2-CB 4.34Å; I104-K106 PolarHBondContact O-N 2.94Å; K106-T112 HydrophobicContact CB-CG2 3.49Å; K106-T112 VanDerWaalsContact CB-CG2 3.49Å; K106-T112 HydrophobicContact CD-CG2 4.09Å; K106-T112 HydrophobicContact CG-CG2 4.44Å; K106-E116 WeakPolarHBondContact CE-OE1 3.35Å; K106-E116 IonicContact NZ-OE1 2.95Å; K106-E116 PolarHBondContact NZ-OE1 3.32Å
107	S	83.3	Confident	91.9	Very high	3 Å²	3	17.5 Å²	17.5	2%	0.021	8%	0.084	C	C	.	.	S	Bend	trans	-68.9	165.7	173.7	-76.5	0	0	0	0	110.8	T112 F254 E257	S107-T112 PolarHBondContact O-OG1 2.95Å; S107-F254 WeakPolarHBondContact CB-O 3.18Å; S107-E257 PolarHBondContact N-OE1 3.47Å; S107-E257 WeakPolarHBondContact OG-CB 3.35Å; S107-E257 VanDerWaalsContact OG-CG 3.22Å; S107-E257 WeakPolarHBondContact OG-CG 3.33Å; S107-E257 PolarHBondContact OG-N 2.98Å
108	G	84.7	Confident	91.9	Very high	0 Å²	0	21.3 Å²	21.3	0%	0	10%	0.101	C	C	.	.	S	Bend	trans	104.6	-3.4	178.2	0	0	0	0	0	116	H110 Y111 T112 F254 L341	G108-H110 PolarHBondContact O-N 3.44Å; G108-Y111 PolarHBondContact O-N 2.9Å; G108-T112 WeakPolarHBondContact CA-OG1 3.13Å; G108-F254 PolarHBondContact N-O 3.33Å; G108-F254 VanDerWaalsContact N-O 3.12Å; G108-F254 WeakPolarHBondContact O-CD1 3.22Å; G108-F254 WeakPolarHBondContact O-CE1 3.45Å; G108-L341 WeakPolarHBondContact O-CD1 3.46Å
109	G	90.4	Very high	91.9	Very high	0 Å²	0	22.2 Å²	22.2	0%	0	11%	0.11	C	C	.	.	T	Hydrogen-bonded Turn	trans	55.7	-128.3	170.1	0	0	0	0	0	113.5	Y111 T112 Y113 N253	G109-Y111 PolarHBondContact O-N 3.18Å; G109-Y111 VanDerWaalsContact O-N 3.13Å; G109-T112 PolarHBondContact O-N 3.18Å; G109-Y113 VanDerWaalsContact O-CD2 3.29Å; G109-Y113 WeakPolarHBondContact O-CD2 3.46Å; G109-Y113 VanDerWaalsContact O-CG 3.24Å; G109-Y113 PolarHBondContact O-N 2.89Å; G109-N253 PolarHBondContact N-O 3.06Å
110	H	91.4	Very high	91.9	Very high	1 Å²	1	25 Å²	25	1%	0.005	13%	0.129	C	C	.	.	H	α-helix	trans	-56.4	-29.6	-178	47	-123.5	0	0	0	114.4	Y97 G108 Y113 I114 R126 E130 F254 A403	Y97-H110 HydrophobicContact CE1-CB 4.42Å; G108-H110 PolarHBondContact O-N 3.44Å; H110-Y113 PolarHBondContact O-N 3.44Å; H110-I114 WeakPolarHBondContact O-CB 3.17Å; H110-I114 WeakPolarHBondContact O-CD1 3.43Å; H110-I114 WeakPolarHBondContact O-CG1 3.38Å; H110-I114 PolarHBondContact O-N 3.43Å; H110-R126 PolarHBondContact CD2-NE 2.87Å; H110-R126 PolarHBondContact CD2-NH2 3.25Å; H110-R126 PolarHBondContact CE1-NH2 2.83Å; H110-R126 PolarHBondContact ND1-NH2 3.48Å; H110-R126 PolarHBondContact NE2-NE 2.73Å; H110-R126 PolarHBondContact NE2-NH2 3.49Å; H110-E130 IonicContact CE1-OE1 3.4Å; H110-E130 IonicContact NE2-OE1 2.72Å; H110-E130 PolarHBondContact NE2-OE1 3.46Å; H110-F254 AromaticContact CD2-CE1 3.94Å; H110-F254 AromaticContact CD2-CZ 3.92Å; H110-F254 AromaticContact CE1-CE1 3.61Å; H110-F254 AromaticContact CE1-CZ 3.11Å; H110-F254 WeakPolarHBondContact CE1-CZ 3.43Å; H110-F254 AromaticContact CG-CZ 3.82Å; H110-F254 AromaticContact ND1-CZ 3.37Å; H110-F254 WeakPolarHBondContact ND1-CZ 3.1Å; H110-F254 AromaticContact NE2-CE1 3.45Å; H110-F254 WeakPolarHBondContact NE2-CE1 3.41Å; H110-F254 AromaticContact NE2-CZ 3.46Å; H110-F254 WeakPolarHBondContact NE2-CZ 3.38Å; H110-A403 HydrophobicContact CB-CB 4.16Å
111	Y	93.8	Very high	91.9	Very high	0 Å²	0	27.4 Å²	27.4	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-64.8	-50.5	-179.9	160	-105.9	0	0	0	109.9	G108 G109 Y113 I114 L115 A123 V127 L341 V344 A345 E348 H350	G108-Y111 PolarHBondContact O-N 2.9Å; G109-Y111 PolarHBondContact O-N 3.18Å; G109-Y111 VanDerWaalsContact O-N 3.13Å; Y111-Y113 VanDerWaalsContact C-N 3.34Å; Y111-Y113 PolarHBondContact O-N 3.44Å; Y111-I114 PolarHBondContact O-N 2.84Å; Y111-L115 HydrophobicContact CE1-CD2 4.25Å; Y111-L115 WeakPolarHBondContact O-CB 3.46Å; Y111-L115 PolarHBondContact O-N 2.99Å; Y111-A123 HydrophobicContact CD2-CB 3.85Å; Y111-A123 VanDerWaalsContact CD2-O 3.26Å; Y111-A123 WeakPolarHBondContact CD2-O 3.46Å; Y111-A123 HydrophobicContact CE2-CB 3.64Å; Y111-A123 WeakPolarHBondContact CE2-O 3.5Å; Y111-V127 HydrophobicContact CD1-CG2 4.44Å; Y111-V127 HydrophobicContact CD2-CB 4.31Å; Y111-V127 HydrophobicContact CD2-CG2 3.14Å; Y111-V127 HydrophobicContact CE2-CG2 3.61Å; Y111-V127 HydrophobicContact CG-CG2 3.59Å; Y111-L341 VanDerWaalsContact CB-CD1 3.48Å; Y111-L341 HydrophobicContact CD1-CD1 4.25Å; Y111-L341 HydrophobicContact CG-CD1 4.04Å; Y111-V344 HydrophobicContact CD1-CG1 4.18Å; Y111-V344 HydrophobicContact CE1-CG1 4.02Å; Y111-A345 HydrophobicContact CE1-CB 4.1Å; Y111-A345 HydrophobicContact CE2-CB 4.36Å; Y111-E348 HydrophobicContact CE1-CB 4.49Å; Y111-E348 HydrophobicContact CE1-CG 4.1Å; Y111-E348 WeakPolarHBondContact OH-CB 3.4Å; Y111-H350 AromaticContact CE2-ND1 3.57Å; Y111-H350 AromaticContact CZ-ND1 3.61Å; Y111-H350 PolarHBondContact OH-ND1 2.91Å
112	T	93.3	Very high	92.1	Very high	3 Å²	3	29.3 Å²	29.3	2%	0.018	15%	0.154	C	C	.	.	H	α-helix	trans	-63.5	-40.9	178.9	-53	0	0	0	0	111.1	I104 K106 S107 G108 G109 L115 E116	I104-T112 HydrophobicContact CG2-CG2 4.06Å; K106-T112 HydrophobicContact CB-CG2 3.49Å; K106-T112 VanDerWaalsContact CB-CG2 3.49Å; K106-T112 HydrophobicContact CD-CG2 4.09Å; K106-T112 HydrophobicContact CG-CG2 4.44Å; S107-T112 PolarHBondContact O-OG1 2.95Å; G108-T112 WeakPolarHBondContact CA-OG1 3.13Å; G109-T112 PolarHBondContact O-N 3.18Å; T112-L115 PolarHBondContact O-N 3.17Å; T112-E116 VanDerWaalsContact O-CG 3.29Å; T112-E116 WeakPolarHBondContact O-CG 3.46Å; T112-E116 PolarHBondContact O-N 3.22Å
113	Y	94.8	Very high	92.2	Very high	1 Å²	1	29.3 Å²	29.3	0%	0.004	15%	0.153	C	C	.	.	H	α-helix	trans	-64.3	-42.6	176.6	-54.2	-27.4	0	0	0	112	Y97 L100 G101 I104 G109 H110 Y111 L115 V117 N253	Y97-Y113 HydrophobicContact CD1-CD2 4.35Å; Y97-Y113 AromaticContact CD1-CE2 3.74Å; Y97-Y113 HydrophobicContact CD1-CE2 3.74Å; Y97-Y113 HydrophobicContact CE1-CD2 4.2Å; Y97-Y113 AromaticContact CE1-CE2 3.98Å; Y97-Y113 HydrophobicContact CE1-CE2 3.98Å; Y97-Y113 HydrophobicContact CG-CE2 4.48Å; L100-Y113 HydrophobicContact CB-CD1 4.2Å; L100-Y113 HydrophobicContact CB-CD2 3.92Å; L100-Y113 HydrophobicContact CB-CE1 4.02Å; L100-Y113 HydrophobicContact CB-CE2 3.71Å; L100-Y113 HydrophobicContact CB-CG 4.18Å; L100-Y113 HydrophobicContact CD1-CD2 3.68Å; L100-Y113 HydrophobicContact CD1-CE2 4.16Å; L100-Y113 HydrophobicContact CD1-CG 4.1Å; L100-Y113 HydrophobicContact CD2-CG 4.43Å; L100-Y113 HydrophobicContact CG-CD2 4.33Å; L100-Y113 HydrophobicContact CG-CG 4.48Å; G101-Y113 WeakPolarHBondContact CA-OH 3.48Å; G101-Y113 PolarHBondContact N-OH 3.38Å; I104-Y113 HydrophobicContact CB-CD1 4.14Å; I104-Y113 HydrophobicContact CB-CE1 4.01Å; I104-Y113 HydrophobicContact CD1-CD1 3.89Å; I104-Y113 HydrophobicContact CG2-CD1 4.27Å; I104-Y113 HydrophobicContact CG2-CE1 4.31Å; G109-Y113 VanDerWaalsContact O-CD2 3.29Å; G109-Y113 WeakPolarHBondContact O-CD2 3.46Å; G109-Y113 VanDerWaalsContact O-CG 3.24Å; G109-Y113 PolarHBondContact O-N 2.89Å; H110-Y113 PolarHBondContact O-N 3.44Å; Y111-Y113 VanDerWaalsContact C-N 3.34Å; Y111-Y113 PolarHBondContact O-N 3.44Å; Y113-L115 VanDerWaalsContact C-N 3.34Å; Y113-V117 WeakPolarHBondContact O-CB 3.44Å; Y113-V117 VanDerWaalsContact O-CG2 3.22Å; Y113-V117 WeakPolarHBondContact O-CG2 3.38Å; Y113-V117 PolarHBondContact O-N 3.08Å; Y113-V117 VanDerWaalsContact O-N 3.17Å; Y113-N253 HydrophobicContact CE2-CB 4.43Å; Y113-N253 WeakPolarHBondContact OH-CB 3.22Å; Y113-N253 PolarHBondContact OH-ND2 3.35Å
114	I	96	Very high	92.3	Very high	0 Å²	0	28.4 Å²	28.4	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-67	-38.5	176.4	-68	164.4	0	0	0	110.6	H110 Y111 V117 F118 G119 P122 A123 R126 F399 L402 A403	H110-I114 WeakPolarHBondContact O-CB 3.17Å; H110-I114 WeakPolarHBondContact O-CD1 3.43Å; H110-I114 WeakPolarHBondContact O-CG1 3.38Å; H110-I114 PolarHBondContact O-N 3.43Å; Y111-I114 PolarHBondContact O-N 2.84Å; I114-V117 PolarHBondContact O-N 3.32Å; I114-F118 HydrophobicContact CG2-CB 4.41Å; I114-F118 HydrophobicContact CG2-CD2 4.14Å; I114-F118 WeakPolarHBondContact O-CA 3.28Å; I114-F118 WeakPolarHBondContact O-CB 3.36Å; I114-F118 PolarHBondContact O-N 3.17Å; I114-G119 PolarHBondContact O-N 3.01Å; I114-P122 HydrophobicContact CG2-CB 3.72Å; I114-A123 HydrophobicContact CG2-CB 4.29Å; I114-R126 HydrophobicContact CD1-CB 4.17Å; I114-R126 HydrophobicContact CD1-CG 3.97Å; I114-F399 HydrophobicContact CD1-CB 4.49Å; I114-F399 HydrophobicContact CD1-CD1 3.91Å; I114-L402 HydrophobicContact CD1-CD2 4.2Å; I114-L402 HydrophobicContact CG1-CD2 4.27Å; I114-L402 HydrophobicContact CG1-CG 4.44Å; I114-L402 HydrophobicContact CG2-CD2 4.26Å; I114-A403 HydrophobicContact CG1-CB 4.37Å
115	L	95.4	Very high	92.6	Very high	26 Å²	26	28.2 Å²	28.2	14%	0.136	15%	0.146	C	C	.	.	H	α-helix	trans	-61.3	-48.7	177.6	-178.4	59.8	0	0	0	112	Y111 T112 Y113 V117 G119 P120 A123 E348	Y111-L115 HydrophobicContact CE1-CD2 4.25Å; Y111-L115 WeakPolarHBondContact O-CB 3.46Å; Y111-L115 PolarHBondContact O-N 2.99Å; T112-L115 PolarHBondContact O-N 3.17Å; Y113-L115 VanDerWaalsContact C-N 3.34Å; L115-V117 VanDerWaalsContact C-N 3.3Å; L115-V117 PolarHBondContact O-N 3.43Å; L115-G119 WeakPolarHBondContact O-CA 3.49Å; L115-G119 PolarHBondContact O-N 3.29Å; L115-P120 HydrophobicContact CD1-CB 4.42Å; L115-P120 HydrophobicContact CD1-CG 4.31Å; L115-A123 HydrophobicContact CB-CB 3.68Å; L115-A123 HydrophobicContact CD1-CB 3.83Å; L115-A123 HydrophobicContact CG-CB 4.34Å; L115-E348 HydrophobicContact CD2-CB 4.5Å; L115-E348 HydrophobicContact CD2-CG 4Å
116	E	93.5	Very high	92.9	Very high	90 Å²	90	23.6 Å²	23.6	42%	0.421	13%	0.126	S	C	.	.	H	α-helix	trans	-66.7	-32	-179.8	-67.6	-67.2	169.4	0	0	112.5	I104 K106 T112	I104-E116 HydrophobicContact CD1-CB 4.19Å; I104-E116 HydrophobicContact CD1-CG 4.34Å; I104-E116 HydrophobicContact CG2-CG 4.09Å; K106-E116 WeakPolarHBondContact CE-OE1 3.35Å; K106-E116 IonicContact NZ-OE1 2.95Å; K106-E116 PolarHBondContact NZ-OE1 3.32Å; T112-E116 VanDerWaalsContact O-CG 3.29Å; T112-E116 WeakPolarHBondContact O-CG 3.46Å; T112-E116 PolarHBondContact O-N 3.22Å
117	V	94.8	Very high	93.4	Very high	17 Å²	17	19.7 Å²	19.7	10%	0.103	11%	0.109	C	C	.	.	H	α-helix	trans	-92.3	-49.8	-174.4	179.1	0	0	0	0	113.3	Y113 I114 L115 Y409 L410	Y113-V117 WeakPolarHBondContact O-CB 3.44Å; Y113-V117 VanDerWaalsContact O-CG2 3.22Å; Y113-V117 WeakPolarHBondContact O-CG2 3.38Å; Y113-V117 PolarHBondContact O-N 3.08Å; Y113-V117 VanDerWaalsContact O-N 3.17Å; I114-V117 PolarHBondContact O-N 3.32Å; L115-V117 VanDerWaalsContact C-N 3.3Å; L115-V117 PolarHBondContact O-N 3.43Å; V117-Y409 HydrophobicContact CG1-CD1 3.62Å; V117-Y409 HydrophobicContact CG1-CE1 4.18Å; V117-Y409 HydrophobicContact CG1-CG 4.46Å; V117-L410 HydrophobicContact CG2-CD1 3.54Å; V117-L410 HydrophobicContact CG2-CD2 4Å; V117-L410 HydrophobicContact CG2-CG 3.63Å
118	F	95.4	Very high	93.9	Very high	80 Å²	80	21.9 Å²	21.9	35%	0.351	12%	0.117	S	C	.	.	H	α-helix	trans	-109.3	-8.9	-170.6	-57.7	-72.2	0	0	0	113.2	I114 P122 L402	I114-F118 HydrophobicContact CG2-CB 4.41Å; I114-F118 HydrophobicContact CG2-CD2 4.14Å; I114-F118 WeakPolarHBondContact O-CA 3.28Å; I114-F118 WeakPolarHBondContact O-CB 3.36Å; I114-F118 PolarHBondContact O-N 3.17Å; F118-P122 HydrophobicContact CB-CB 4.11Å; F118-P122 HydrophobicContact CB-CG 3.95Å; F118-L402 HydrophobicContact CD2-CD1 4.12Å; F118-L402 HydrophobicContact CD2-CD2 4.32Å; F118-L402 HydrophobicContact CD2-CG 4Å; F118-L402 HydrophobicContact CE1-CD1 4.18Å; F118-L402 HydrophobicContact CE2-CD1 3.56Å; F118-L402 HydrophobicContact CE2-CD2 4.41Å; F118-L402 HydrophobicContact CE2-CG 3.61Å; F118-L402 WeakPolarHBondContact CE2-O 3.13Å; F118-L402 HydrophobicContact CZ-CD1 3.59Å; F118-L402 HydrophobicContact CZ-CG 4.17Å
119	G	94.3	Very high	94.2	Very high	19 Å²	19	21.9 Å²	21.9	20%	0.196	12%	0.117	C	C	.	.			trans	89.9	-171.6	175.1	0	0	0	0	0	115.1	I114 L115 A123	I114-G119 PolarHBondContact O-N 3.01Å; L115-G119 WeakPolarHBondContact O-CA 3.49Å; L115-G119 PolarHBondContact O-N 3.29Å; G119-A123 WeakPolarHBondContact O-CB 3.39Å; G119-A123 PolarHBondContact O-N 3.08Å
120	P	94.8	Very high	94.3	Very high	60 Å²	60	21.9 Å²	21.9	39%	0.39	12%	0.117	S	C	.	.	H	α-helix	trans	-64.8	-43.4	-166.6	-29.4	38.9	0	0	0	115.9	L115 A123 F124 H350 Y464	L115-P120 HydrophobicContact CD1-CB 4.42Å; L115-P120 HydrophobicContact CD1-CG 4.31Å; P120-A123 PolarHBondContact O-N 3.11Å; P120-F124 PolarHBondContact O-N 2.95Å; P120-H350 PolarHBondContact O-CE1 3.32Å; P120-Y464 HydrophobicContact CB-CE2 4.36Å; P120-Y464 VanDerWaalsContact CB-OH 3.26Å; P120-Y464 WeakPolarHBondContact CB-OH 3.39Å
121	L	95.5	Very high	94.2	Very high	51 Å²	51	22.7 Å²	22.7	27%	0.267	12%	0.121	S	C	.	.	H	α-helix	trans	-62.2	-54.8	-175.4	166.7	70.4	0	0	0	112.2	A123 F124 V125 V461 Y464	L121-A123 PolarHBondContact O-N 3.46Å; L121-F124 PolarHBondContact O-N 3.05Å; L121-F124 VanDerWaalsContact O-N 3.17Å; L121-V125 HydrophobicContact CD1-CG2 4.18Å; L121-V125 WeakPolarHBondContact O-CG2 3.1Å; L121-V125 PolarHBondContact O-N 3.04Å; L121-V461 HydrophobicContact CD1-CG1 4.34Å; L121-Y464 HydrophobicContact CB-CD1 3.98Å; L121-Y464 HydrophobicContact CB-CE1 3.74Å; L121-Y464 HydrophobicContact CD1-CD1 3.33Å; L121-Y464 HydrophobicContact CD1-CE1 4.02Å; L121-Y464 HydrophobicContact CD1-CG 3.64Å; L121-Y464 HydrophobicContact CG-CD1 4.22Å; L121-Y464 HydrophobicContact CG-CE1 4.45Å
122	P	95.7	Very high	94	Very high	40 Å²	40	25.3 Å²	25.3	26%	0.26	14%	0.135	S	C	.	.	H	α-helix	trans	-60.5	-33.9	177.3	-26.3	37.3	0	0	0	113.3	I114 F118 V125 R126	I114-P122 HydrophobicContact CG2-CB 3.72Å; F118-P122 HydrophobicContact CB-CB 4.11Å; F118-P122 HydrophobicContact CB-CG 3.95Å; P122-V125 PolarHBondContact O-N 3.25Å; P122-R126 WeakPolarHBondContact O-CB 3.43Å; P122-R126 PolarHBondContact O-N 2.98Å
123	A	95.3	Very high	93.6	Very high	0 Å²	0	25.2 Å²	25.2	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-67.9	-40	176.2	0	0	0	0	0	112.1	Y111 I114 L115 G119 P120 L121 R126 V127	Y111-A123 HydrophobicContact CD2-CB 3.85Å; Y111-A123 VanDerWaalsContact CD2-O 3.26Å; Y111-A123 WeakPolarHBondContact CD2-O 3.46Å; Y111-A123 HydrophobicContact CE2-CB 3.64Å; Y111-A123 WeakPolarHBondContact CE2-O 3.5Å; I114-A123 HydrophobicContact CG2-CB 4.29Å; L115-A123 HydrophobicContact CB-CB 3.68Å; L115-A123 HydrophobicContact CD1-CB 3.83Å; L115-A123 HydrophobicContact CG-CB 4.34Å; G119-A123 WeakPolarHBondContact O-CB 3.39Å; G119-A123 PolarHBondContact O-N 3.08Å; P120-A123 PolarHBondContact O-N 3.11Å; L121-A123 PolarHBondContact O-N 3.46Å; A123-R126 WeakPolarHBondContact O-CB 3.41Å; A123-R126 PolarHBondContact O-N 3.38Å; A123-V127 PolarHBondContact O-N 3.33Å; A123-V127 VanDerWaalsContact O-N 3.11Å
124	F	95.5	Very high	93.3	Very high	4 Å²	4	25.3 Å²	25.3	2%	0.018	14%	0.135	C	C	.	.	H	α-helix	trans	-63.3	-48.8	172.8	178.1	-86.5	0	0	0	111.2	P120 L121 R126 V127 W128 H350 G460 A463 Y464 I468	P120-F124 PolarHBondContact O-N 2.95Å; L121-F124 PolarHBondContact O-N 3.05Å; L121-F124 VanDerWaalsContact O-N 3.17Å; F124-R126 PolarHBondContact O-N 3.41Å; F124-V127 PolarHBondContact O-N 3.2Å; F124-W128 HydrophobicContact CD1-CB 4.37Å; F124-W128 HydrophobicContact CE1-CB 4.12Å; F124-W128 HydrophobicContact CE1-CD2 4.26Å; F124-W128 HydrophobicContact CE1-CE3 4.01Å; F124-W128 HydrophobicContact CE1-CG 4.34Å; F124-W128 HydrophobicContact CZ-CD2 4.49Å; F124-W128 AromaticContact CZ-CE3 3.8Å; F124-W128 HydrophobicContact CZ-CE3 3.8Å; F124-W128 HydrophobicContact CZ-CZ3 4.35Å; F124-W128 WeakPolarHBondContact O-CB 3.43Å; F124-W128 PolarHBondContact O-N 3.35Å; F124-H350 HydrophobicContact CD2-CB 3.93Å; F124-H350 WeakPolarHBondContact CD2-O 3.33Å; F124-H350 WeakPolarHBondContact CE2-O 3.15Å; F124-G460 WeakPolarHBondContact CD1-O 3.47Å; F124-G460 VanDerWaalsContact CE1-O 3.25Å; F124-G460 WeakPolarHBondContact CE1-O 3.13Å; F124-A463 HydrophobicContact CE1-CB 3.93Å; F124-A463 HydrophobicContact CZ-CB 4.2Å; F124-Y464 HydrophobicContact CB-CD2 3.39Å; F124-Y464 HydrophobicContact CB-CE2 3.93Å; F124-Y464 HydrophobicContact CB-CG 4.25Å; F124-Y464 AromaticContact CD1-CD2 3.86Å; F124-Y464 HydrophobicContact CD1-CD2 3.86Å; F124-Y464 HydrophobicContact CD1-CG 4.14Å; F124-Y464 AromaticContact CD2-CD2 3.83Å; F124-Y464 HydrophobicContact CD2-CD2 3.83Å; F124-Y464 AromaticContact CG-CD2 3.42Å; F124-Y464 HydrophobicContact CG-CD2 3.42Å; F124-Y464 VanDerWaalsContact CG-CD2 3.42Å; F124-Y464 HydrophobicContact CG-CE2 4.32Å; F124-Y464 HydrophobicContact CG-CG 4.16Å; F124-I468 HydrophobicContact CD2-CD1 4.2Å; F124-I468 HydrophobicContact CD2-CG1 3.78Å; F124-I468 HydrophobicContact CE2-CD1 3.98Å; F124-I468 HydrophobicContact CE2-CG1 3.76Å
125	V	95.6	Very high	93	Very high	14 Å²	14	25.6 Å²	25.6	9%	0.085	14%	0.136	C	C	.	.	H	α-helix	trans	-57.5	-39.8	178.3	-178.3	0	0	0	0	110.2	L121 P122 V127 W128 V129 F399 T457 V461	L121-V125 HydrophobicContact CD1-CG2 4.18Å; L121-V125 WeakPolarHBondContact O-CG2 3.1Å; L121-V125 PolarHBondContact O-N 3.04Å; P122-V125 PolarHBondContact O-N 3.25Å; V125-V127 PolarHBondContact O-N 2.9Å; V125-W128 PolarHBondContact O-N 3.49Å; V125-V129 HydrophobicContact CG1-CG2 4.42Å; V125-V129 WeakPolarHBondContact O-CG2 3.35Å; V125-V129 PolarHBondContact O-N 2.84Å; V125-F399 HydrophobicContact CG1-CZ 4Å; V125-T457 HydrophobicContact CG1-CG2 3.88Å; V125-T457 VanDerWaalsContact CG1-O 3.29Å; V125-T457 WeakPolarHBondContact CG1-O 3.36Å; V125-V461 HydrophobicContact CG2-CG2 4.02Å
126	R	93.8	Very high	92.7	Very high	3 Å²	3	24.4 Å²	24.4	1%	0.011	13%	0.13	C	C	.	.	H	α-helix	trans	-55.4	-52	173.5	173.6	69.7	-168.6	87.5	-14.3	112.1	H110 I114 P122 A123 F124 E130 F399	H110-R126 PolarHBondContact CD2-NE 2.87Å; H110-R126 PolarHBondContact CD2-NH2 3.25Å; H110-R126 PolarHBondContact CE1-NH2 2.83Å; H110-R126 PolarHBondContact ND1-NH2 3.48Å; H110-R126 PolarHBondContact NE2-NE 2.73Å; H110-R126 PolarHBondContact NE2-NH2 3.49Å; I114-R126 HydrophobicContact CD1-CB 4.17Å; I114-R126 HydrophobicContact CD1-CG 3.97Å; P122-R126 WeakPolarHBondContact O-CB 3.43Å; P122-R126 PolarHBondContact O-N 2.98Å; A123-R126 WeakPolarHBondContact O-CB 3.41Å; A123-R126 PolarHBondContact O-N 3.38Å; F124-R126 PolarHBondContact O-N 3.41Å; R126-E130 IonicContact CZ-OE1 3.53Å; R126-E130 IonicContact CZ-OE2 3.93Å; R126-E130 VanDerWaalsContact NH1-CB 3.28Å; R126-E130 IonicContact NH1-OE1 2.69Å; R126-E130 IonicContact NH1-OE2 3.81Å; R126-E130 PolarHBondContact NH1-OE2 3.12Å; R126-E130 VanDerWaalsContact NH2-CD 3.31Å; R126-E130 IonicContact NH2-OE1 3.1Å; R126-E130 PolarHBondContact NH2-OE1 2.9Å; R126-E130 IonicContact NH2-OE2 3.38Å; R126-E130 PolarHBondContact NH2-OE2 2.81Å; R126-E130 WeakPolarHBondContact O-CB 3.26Å; R126-E130 PolarHBondContact O-N 3.32Å; R126-F399 HydrophobicContact CB-CD1 3.96Å; R126-F399 HydrophobicContact CB-CE1 3.84Å; R126-F399 HydrophobicContact CB-CG 4.48Å; R126-F399 HydrophobicContact CB-CZ 4.29Å; R126-F399 HydrophobicContact CG-CD1 4.25Å; R126-F399 HydrophobicContact CG-CG 4.39Å
127	V	93.6	Very high	92.5	Very high	1 Å²	1	20.1 Å²	20.1	1%	0.006	11%	0.109	C	C	.	.	H	α-helix	trans	-71.5	-35	-177.5	165.9	0	0	0	0	111.8	Y111 A123 F124 V125 E130 L131 L341 A345 L351	Y111-V127 HydrophobicContact CD1-CG2 4.44Å; Y111-V127 HydrophobicContact CD2-CB 4.31Å; Y111-V127 HydrophobicContact CD2-CG2 3.14Å; Y111-V127 HydrophobicContact CE2-CG2 3.61Å; Y111-V127 HydrophobicContact CG-CG2 3.59Å; A123-V127 PolarHBondContact O-N 3.33Å; A123-V127 VanDerWaalsContact O-N 3.11Å; F124-V127 PolarHBondContact O-N 3.2Å; V125-V127 PolarHBondContact O-N 2.9Å; V127-E130 VanDerWaalsContact O-CB 3.3Å; V127-E130 WeakPolarHBondContact O-CB 3.44Å; V127-E130 PolarHBondContact O-N 3.25Å; V127-L131 WeakPolarHBondContact O-CB 3.26Å; V127-L131 PolarHBondContact O-N 3.5Å; V127-L341 HydrophobicContact CG2-CD1 4.23Å; V127-A345 HydrophobicContact CB-CB 4.32Å; V127-A345 HydrophobicContact CG1-CB 3.76Å; V127-A345 HydrophobicContact CG2-CB 3.78Å; V127-L351 HydrophobicContact CG1-CD1 3.68Å; V127-L351 HydrophobicContact CG1-CD2 4.07Å; V127-L351 HydrophobicContact CG1-CG 3.86Å
128	W	94	Very high	92.2	Very high	50 Å²	50	19.7 Å²	19.7	19%	0.189	11%	0.108	C	C	.	.	H	α-helix	trans	-56.2	-51.9	174.2	-177.4	-101.4	0	0	0	111.4	F124 V125 E130 L131 L132 T459 A463 F467	F124-W128 HydrophobicContact CD1-CB 4.37Å; F124-W128 HydrophobicContact CE1-CB 4.12Å; F124-W128 HydrophobicContact CE1-CD2 4.26Å; F124-W128 HydrophobicContact CE1-CE3 4.01Å; F124-W128 HydrophobicContact CE1-CG 4.34Å; F124-W128 HydrophobicContact CZ-CD2 4.49Å; F124-W128 AromaticContact CZ-CE3 3.8Å; F124-W128 HydrophobicContact CZ-CE3 3.8Å; F124-W128 HydrophobicContact CZ-CZ3 4.35Å; F124-W128 WeakPolarHBondContact O-CB 3.43Å; F124-W128 PolarHBondContact O-N 3.35Å; V125-W128 PolarHBondContact O-N 3.49Å; W128-E130 VanDerWaalsContact C-N 3.33Å; W128-E130 PolarHBondContact O-N 2.76Å; W128-L131 PolarHBondContact O-N 3.34Å; W128-L132 HydrophobicContact CD2-CD1 4.02Å; W128-L132 VanDerWaalsContact CE2-CD1 3.42Å; W128-L132 HydrophobicContact CG-CD1 4.42Å; W128-L132 HydrophobicContact CH2-CD1 4.32Å; W128-L132 HydrophobicContact CZ2-CD1 3.61Å; W128-L132 WeakPolarHBondContact O-CG 3.27Å; W128-L132 PolarHBondContact O-N 2.95Å; W128-L132 VanDerWaalsContact O-N 3.08Å; W128-T459 PolarHBondContact NE1-OG1 3.13Å; W128-A463 HydrophobicContact CD2-CB 4.1Å; W128-A463 HydrophobicContact CE3-CB 4.11Å; W128-A463 HydrophobicContact CH2-CB 3.78Å; W128-A463 HydrophobicContact CZ2-CB 3.74Å; W128-A463 HydrophobicContact CZ3-CB 3.96Å; W128-F467 HydrophobicContact CH2-CE2 4.12Å; W128-F467 HydrophobicContact CZ3-CD2 4.4Å; W128-F467 HydrophobicContact CZ3-CE2 4.21Å
129	V	92.4	Very high	91.9	Very high	0 Å²	0	16.3 Å²	16.3	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-70.4	-32.2	178.7	179.8	0	0	0	0	111.9	V125 L131 I133 I134 A395 F399 T457	V125-V129 HydrophobicContact CG1-CG2 4.42Å; V125-V129 WeakPolarHBondContact O-CG2 3.35Å; V125-V129 PolarHBondContact O-N 2.84Å; V129-L131 VanDerWaalsContact C-N 3.35Å; V129-I133 HydrophobicContact CG1-CB 4.3Å; V129-I133 HydrophobicContact CG1-CD1 4.14Å; V129-I133 WeakPolarHBondContact O-CB 3.47Å; V129-I133 PolarHBondContact O-N 3.05Å; V129-I134 HydrophobicContact CG1-CD1 3.91Å; V129-I134 HydrophobicContact CG1-CG1 4.05Å; V129-I134 PolarHBondContact O-N 3.06Å; V129-A395 HydrophobicContact CG1-CB 3.64Å; V129-F399 HydrophobicContact CB-CE2 4.09Å; V129-F399 HydrophobicContact CG1-CE2 4.3Å; V129-F399 HydrophobicContact CG2-CE2 4.25Å; V129-T457 VanDerWaalsContact CG2-CA 3.48Å; V129-T457 HydrophobicContact CG2-CG2 3.96Å
130	E	91.2	Very high	91.8	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.084	C	C	.	.	I	π-helix	trans	-58.6	-48.9	173.1	-165.3	77.6	143.4	0	0	112.1	H110 R126 V127 W128 I134 R135 L341 F342	H110-E130 IonicContact CE1-OE1 3.4Å; H110-E130 IonicContact NE2-OE1 2.72Å; H110-E130 PolarHBondContact NE2-OE1 3.46Å; R126-E130 IonicContact CZ-OE1 3.53Å; R126-E130 IonicContact CZ-OE2 3.93Å; R126-E130 VanDerWaalsContact NH1-CB 3.28Å; R126-E130 IonicContact NH1-OE1 2.69Å; R126-E130 IonicContact NH1-OE2 3.81Å; R126-E130 PolarHBondContact NH1-OE2 3.12Å; R126-E130 VanDerWaalsContact NH2-CD 3.31Å; R126-E130 IonicContact NH2-OE1 3.1Å; R126-E130 PolarHBondContact NH2-OE1 2.9Å; R126-E130 IonicContact NH2-OE2 3.38Å; R126-E130 PolarHBondContact NH2-OE2 2.81Å; R126-E130 WeakPolarHBondContact O-CB 3.26Å; R126-E130 PolarHBondContact O-N 3.32Å; V127-E130 VanDerWaalsContact O-CB 3.3Å; V127-E130 WeakPolarHBondContact O-CB 3.44Å; V127-E130 PolarHBondContact O-N 3.25Å; W128-E130 VanDerWaalsContact C-N 3.33Å; W128-E130 PolarHBondContact O-N 2.76Å; E130-I134 WeakPolarHBondContact OE2-CB 3.38Å; E130-I134 WeakPolarHBondContact OE2-CD1 3.42Å; E130-I134 WeakPolarHBondContact OE2-CG2 3.34Å; E130-R135 HydrophobicContact CG-CG 3.57Å; E130-R135 WeakPolarHBondContact O-CB 3.33Å; E130-R135 WeakPolarHBondContact O-CG 3.43Å; E130-R135 PolarHBondContact O-N 3.3Å; E130-R135 IonicContact OE1-CZ 3.06Å; E130-R135 IonicContact OE1-NE 2.84Å; E130-R135 PolarHBondContact OE1-NE 3.45Å; E130-R135 IonicContact OE1-NH2 3.31Å; E130-R135 PolarHBondContact OE1-NH2 3.28Å; E130-R135 IonicContact OE2-NE 3.25Å; E130-L341 HydrophobicContact CB-CD2 4.45Å; E130-L341 HydrophobicContact CG-CD2 3.52Å; E130-L341 VanDerWaalsContact OE1-CD2 3.28Å; E130-L341 WeakPolarHBondContact OE1-CD2 3.42Å; E130-F342 HydrophobicContact CG-CE1 4.42Å
131	L	90.4	Very high	91.5	Very high	17 Å²	17	12.5 Å²	12.5	9%	0.089	7%	0.066	C	C	.	.	I	π-helix	trans	-68.3	-47.7	-175.2	178	66.2	0	0	0	111.3	V127 W128 V129 P136 F342 L351 V371 L375	V127-L131 WeakPolarHBondContact O-CB 3.26Å; V127-L131 PolarHBondContact O-N 3.5Å; W128-L131 PolarHBondContact O-N 3.34Å; V129-L131 VanDerWaalsContact C-N 3.35Å; L131-P136 VanDerWaalsContact O-CD 3.28Å; L131-P136 WeakPolarHBondContact O-CD 3.49Å; L131-P136 WeakPolarHBondContact O-CG 3.42Å; L131-F342 HydrophobicContact CB-CE1 3.92Å; L131-F342 HydrophobicContact CB-CZ 4.01Å; L131-F342 HydrophobicContact CD1-CD1 4.47Å; L131-F342 HydrophobicContact CD1-CD2 4.21Å; L131-F342 HydrophobicContact CD1-CE1 3.81Å; L131-F342 HydrophobicContact CD1-CE2 3.49Å; L131-F342 VanDerWaalsContact CD1-CE2 3.49Å; L131-F342 HydrophobicContact CD1-CZ 3.28Å; L131-F342 HydrophobicContact CG-CE1 4.47Å; L131-F342 HydrophobicContact CG-CZ 4.26Å; L131-L351 HydrophobicContact CD2-CD2 4.23Å; L131-V371 HydrophobicContact CD1-CG1 3.99Å; L131-L375 HydrophobicContact CD1-CD1 4.17Å; L131-L375 HydrophobicContact CG-CD1 4.28Å; L131-L375 WeakPolarHBondContact O-CD1 3.46Å
132	L	88.8	Confident	91.2	Very high	55 Å²	55	11.4 Å²	11.4	29%	0.288	6%	0.06	S	C	.	.	I	π-helix	trans	-82.7	-34	-172.8	-64	-178.6	0	0	0	113.6	W128	W128-L132 HydrophobicContact CD2-CD1 4.02Å; W128-L132 VanDerWaalsContact CE2-CD1 3.42Å; W128-L132 HydrophobicContact CG-CD1 4.42Å; W128-L132 HydrophobicContact CH2-CD1 4.32Å; W128-L132 HydrophobicContact CZ2-CD1 3.61Å; W128-L132 WeakPolarHBondContact O-CG 3.27Å; W128-L132 PolarHBondContact O-N 2.95Å; W128-L132 VanDerWaalsContact O-N 3.08Å
133	I	84.9	Confident	91	Very high	2 Å²	2	9.5 Å²	9.5	1%	0.01	5%	0.048	C	C	.	.	I	π-helix	trans	-119.9	-67.4	-169.5	-63.9	169.7	0	0	0	111.8	V129 R135 P136 A137 F391 I456	V129-I133 HydrophobicContact CG1-CB 4.3Å; V129-I133 HydrophobicContact CG1-CD1 4.14Å; V129-I133 WeakPolarHBondContact O-CB 3.47Å; V129-I133 PolarHBondContact O-N 3.05Å; I133-R135 VanDerWaalsContact C-N 3.32Å; I133-R135 PolarHBondContact O-N 3.09Å; I133-P136 WeakPolarHBondContact O-CD 3.3Å; I133-A137 WeakPolarHBondContact O-CB 3.34Å; I133-A137 PolarHBondContact O-N 3.24Å; I133-F391 HydrophobicContact CB-CE1 3.97Å; I133-F391 HydrophobicContact CB-CZ 4.32Å; I133-F391 HydrophobicContact CD1-CE1 4.22Å; I133-F391 HydrophobicContact CD1-CE2 4.39Å; I133-F391 HydrophobicContact CD1-CZ 3.69Å; I133-F391 HydrophobicContact CG1-CE1 3.77Å; I133-F391 HydrophobicContact CG1-CZ 3.66Å; I133-F391 HydrophobicContact CG2-CD1 3.61Å; I133-F391 HydrophobicContact CG2-CE1 3.18Å; I133-F391 HydrophobicContact CG2-CZ 3.76Å; I133-I456 HydrophobicContact CD1-CB 3.47Å; I133-I456 VanDerWaalsContact CD1-CB 3.47Å; I133-I456 HydrophobicContact CD1-CD1 3.81Å; I133-I456 HydrophobicContact CD1-CG1 4.24Å; I133-I456 HydrophobicContact CD1-CG2 3.24Å; I133-I456 HydrophobicContact CG1-CD1 4.3Å; I133-I456 HydrophobicContact CG1-CG2 3.93Å
134	I	88.9	Confident	90.8	Very high	2 Å²	2	10.5 Å²	10.5	1%	0.01	5%	0.053	C	C	.	.	I	π-helix	trans	-63.4	-42.2	-159.2	-64.1	168.8	0	0	0	110.6	V129 E130 A138 A395	V129-I134 HydrophobicContact CG1-CD1 3.91Å; V129-I134 HydrophobicContact CG1-CG1 4.05Å; V129-I134 PolarHBondContact O-N 3.06Å; E130-I134 WeakPolarHBondContact OE2-CB 3.38Å; E130-I134 WeakPolarHBondContact OE2-CD1 3.42Å; E130-I134 WeakPolarHBondContact OE2-CG2 3.34Å; I134-A138 WeakPolarHBondContact O-CB 3.44Å; I134-A138 PolarHBondContact O-N 3.22Å; I134-A395 HydrophobicContact CD1-CB 3.92Å; I134-A395 HydrophobicContact CG1-CB 4.1Å
135	R	88.5	Confident	90.5	Very high	7 Å²	7	10.5 Å²	10.5	3%	0.026	5%	0.053	C	C	.	.	H	α-helix	trans	-79.8	-46.9	-176.2	-59.4	-57.6	-173.9	173.7	-5.8	113.7	E130 I133 A137 A138 T139 Y251 V338 L372	E130-R135 HydrophobicContact CG-CG 3.57Å; E130-R135 WeakPolarHBondContact O-CB 3.33Å; E130-R135 WeakPolarHBondContact O-CG 3.43Å; E130-R135 PolarHBondContact O-N 3.3Å; E130-R135 IonicContact OE1-CZ 3.06Å; E130-R135 IonicContact OE1-NE 2.84Å; E130-R135 PolarHBondContact OE1-NE 3.45Å; E130-R135 IonicContact OE1-NH2 3.31Å; E130-R135 PolarHBondContact OE1-NH2 3.28Å; E130-R135 IonicContact OE2-NE 3.25Å; I133-R135 VanDerWaalsContact C-N 3.32Å; I133-R135 PolarHBondContact O-N 3.09Å; R135-A137 VanDerWaalsContact C-N 3.35Å; R135-A137 PolarHBondContact O-N 3.12Å; R135-A138 PolarHBondContact O-N 2.98Å; R135-T139 VanDerWaalsContact O-CB 3.29Å; R135-T139 WeakPolarHBondContact O-CB 3.32Å; R135-T139 PolarHBondContact O-N 2.88Å; R135-T139 PolarHBondContact O-OG1 3.43Å; R135-Y251 VanDerWaalsContact NH1-CZ 3.32Å; R135-Y251 PolarHBondContact NH1-OH 3.44Å; R135-V338 HydrophobicContact CB-CG1 4.38Å; R135-V338 HydrophobicContact CB-CG2 4.15Å; R135-V338 HydrophobicContact CG-CG1 4.12Å; R135-V338 HydrophobicContact CG-CG2 3.58Å; R135-L372 HydrophobicContact CB-CD1 3.88Å
136	P	90	Very high	90.3	Very high	0 Å²	0	10.9 Å²	10.9	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-54	-50.2	171.4	-30	38.5	0	0	0	112.4	L131 I133 T139 A140 L372 L375 M379	L131-P136 VanDerWaalsContact O-CD 3.28Å; L131-P136 WeakPolarHBondContact O-CD 3.49Å; L131-P136 WeakPolarHBondContact O-CG 3.42Å; I133-P136 WeakPolarHBondContact O-CD 3.3Å; P136-T139 PolarHBondContact O-N 3.38Å; P136-A140 VanDerWaalsContact O-CB 3.29Å; P136-A140 WeakPolarHBondContact O-CB 3.37Å; P136-A140 PolarHBondContact O-N 3.29Å; P136-L372 HydrophobicContact CG-CD1 4.08Å; P136-L375 HydrophobicContact CB-CB 4.15Å; P136-L375 HydrophobicContact CG-CB 3.67Å; P136-L375 HydrophobicContact CG-CD1 4.42Å; P136-M379 HydrophobicContact CB-CB 4.4Å; P136-M379 HydrophobicContact CB-CG 3.64Å
137	A	88.9	Confident	90.3	Very high	0 Å²	0	10.7 Å²	10.7	0%	0	5%	0.053	C	C	.	.	H	α-helix	trans	-65.4	-45.8	-178.4	0	0	0	0	0	112.5	I133 R135 T139 A140 V141 L388 L392	I133-A137 WeakPolarHBondContact O-CB 3.34Å; I133-A137 PolarHBondContact O-N 3.24Å; R135-A137 VanDerWaalsContact C-N 3.35Å; R135-A137 PolarHBondContact O-N 3.12Å; A137-T139 VanDerWaalsContact C-N 3.32Å; A137-T139 PolarHBondContact O-N 3.37Å; A137-A140 PolarHBondContact O-N 2.9Å; A137-V141 WeakPolarHBondContact O-CG2 3.17Å; A137-V141 PolarHBondContact O-N 2.91Å; A137-L388 HydrophobicContact CB-CD2 4.1Å; A137-L392 HydrophobicContact CB-CB 4.06Å; A137-L392 HydrophobicContact CB-CD2 4.04Å
138	A	88.6	Confident	90.1	Very high	8 Å²	8	14.6 Å²	14.6	7%	0.066	7%	0.068	C	C	.	.	H	α-helix	trans	-62.2	-40.6	178.4	0	0	0	0	0	112.4	I134 R135 I142 L392	I134-A138 WeakPolarHBondContact O-CB 3.44Å; I134-A138 PolarHBondContact O-N 3.22Å; R135-A138 PolarHBondContact O-N 2.98Å; A138-I142 VanDerWaalsContact O-CG1 3.3Å; A138-I142 WeakPolarHBondContact O-CG1 3.44Å; A138-I142 PolarHBondContact O-N 3.39Å; A138-L392 HydrophobicContact CB-CD2 4.19Å
139	T	90.2	Very high	89.9	Confident	9 Å²	9	12.5 Å²	12.5	6%	0.055	6%	0.06	C	C	.	.	H	α-helix	trans	-68.8	-41.7	179.1	-50.8	0	0	0	0	110.3	R135 P136 A137 I142 S143 L173 T376	R135-T139 VanDerWaalsContact O-CB 3.29Å; R135-T139 WeakPolarHBondContact O-CB 3.32Å; R135-T139 PolarHBondContact O-N 2.88Å; R135-T139 PolarHBondContact O-OG1 3.43Å; P136-T139 PolarHBondContact O-N 3.38Å; A137-T139 VanDerWaalsContact C-N 3.32Å; A137-T139 PolarHBondContact O-N 3.37Å; T139-I142 PolarHBondContact O-N 3.14Å; T139-S143 VanDerWaalsContact O-CB 3.26Å; T139-S143 WeakPolarHBondContact O-CB 3.25Å; T139-S143 PolarHBondContact O-N 2.94Å; T139-S143 PolarHBondContact O-OG 3.19Å; T139-S143 VanDerWaalsContact O-OG 3.12Å; T139-L173 HydrophobicContact CG2-CD1 3.62Å; T139-T376 HydrophobicContact CG2-CG2 3.83Å
140	A	90.8	Very high	89.9	Confident	0 Å²	0	14.8 Å²	14.8	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-60.6	-45.2	176.8	0	0	0	0	0	112.6	P136 A137 I142 S143 L144 T376 M379 L388	P136-A140 VanDerWaalsContact O-CB 3.29Å; P136-A140 WeakPolarHBondContact O-CB 3.37Å; P136-A140 PolarHBondContact O-N 3.29Å; A137-A140 PolarHBondContact O-N 2.9Å; A140-I142 PolarHBondContact O-N 2.97Å; A140-S143 VanDerWaalsContact CA-OG 3.31Å; A140-S143 WeakPolarHBondContact CA-OG 3.45Å; A140-S143 PolarHBondContact O-N 2.99Å; A140-S143 PolarHBondContact O-OG 3.41Å; A140-L144 WeakPolarHBondContact O-CB 3.33Å; A140-L144 WeakPolarHBondContact O-CG 3.35Å; A140-L144 PolarHBondContact O-N 3.44Å; A140-T376 HydrophobicContact CB-CG2 4.36Å; A140-M379 HydrophobicContact CB-CB 4.05Å; A140-L388 HydrophobicContact CB-CD1 4.26Å
141	V	88.3	Confident	90	Very high	0 Å²	0	15.8 Å²	15.8	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-61.3	-47.6	177.7	170.7	0	0	0	0	111.3	A137 S143 L144 A145 Y244 L385 L388 L389	A137-V141 WeakPolarHBondContact O-CG2 3.17Å; A137-V141 PolarHBondContact O-N 2.91Å; V141-S143 VanDerWaalsContact C-N 3.3Å; V141-S143 PolarHBondContact O-N 3.26Å; V141-L144 PolarHBondContact O-N 2.93Å; V141-A145 PolarHBondContact O-N 2.73Å; V141-A145 VanDerWaalsContact O-N 3.17Å; V141-Y244 VanDerWaalsContact CG1-OH 3.26Å; V141-Y244 WeakPolarHBondContact CG1-OH 3.43Å; V141-L385 HydrophobicContact CG1-CD1 4.41Å; V141-L385 HydrophobicContact CG1-CD2 4.28Å; V141-L385 HydrophobicContact CG1-CG 4.07Å; V141-L388 HydrophobicContact CG2-CB 3.65Å; V141-L388 HydrophobicContact CG2-CD1 4.2Å; V141-L389 HydrophobicContact CG1-CD2 3.9Å; V141-L389 HydrophobicContact CG1-CG 4.25Å; V141-L389 HydrophobicContact CG2-CD2 4.26Å; V141-L389 HydrophobicContact CG2-CG 4.29Å
142	I	90	Very high	89.8	Confident	28 Å²	28	16.7 Å²	16.7	14%	0.144	8%	0.081	C	C	.	.	H	α-helix	trans	-64.5	-38.8	178.8	-65.3	169	0	0	0	110.5	A138 T139 A140 A145 F146 C327 M331	A138-I142 VanDerWaalsContact O-CG1 3.3Å; A138-I142 WeakPolarHBondContact O-CG1 3.44Å; A138-I142 PolarHBondContact O-N 3.39Å; T139-I142 PolarHBondContact O-N 3.14Å; A140-I142 PolarHBondContact O-N 2.97Å; I142-A145 PolarHBondContact O-N 3.09Å; I142-F146 PolarHBondContact O-N 3.47Å; I142-F146 VanDerWaalsContact O-N 3.1Å; I142-C327 HydrophobicContact CG2-CB 4.35Å; I142-C327 WeakPolarHBondContact CG2-O 3.26Å; I142-M331 HydrophobicContact CB-CG 4.34Å; I142-M331 HydrophobicContact CG2-CG 3.65Å
143	S	92.1	Very high	89.7	Confident	0 Å²	0	15.5 Å²	15.5	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-70.6	-37.3	-179.6	69.6	0	0	0	0	112.3	T139 A140 V141 A145 F146 G147 T169 M331	T139-S143 VanDerWaalsContact O-CB 3.26Å; T139-S143 WeakPolarHBondContact O-CB 3.25Å; T139-S143 PolarHBondContact O-N 2.94Å; T139-S143 PolarHBondContact O-OG 3.19Å; T139-S143 VanDerWaalsContact O-OG 3.12Å; A140-S143 VanDerWaalsContact CA-OG 3.31Å; A140-S143 WeakPolarHBondContact CA-OG 3.45Å; A140-S143 PolarHBondContact O-N 2.99Å; A140-S143 PolarHBondContact O-OG 3.41Å; V141-S143 VanDerWaalsContact C-N 3.3Å; V141-S143 PolarHBondContact O-N 3.26Å; S143-A145 VanDerWaalsContact C-N 3.32Å; S143-A145 PolarHBondContact O-N 3.11Å; S143-F146 WeakPolarHBondContact O-CA 3.36Å; S143-F146 VanDerWaalsContact O-CB 3.28Å; S143-F146 WeakPolarHBondContact O-CB 3.2Å; S143-F146 PolarHBondContact O-N 3.4Å; S143-F146 VanDerWaalsContact O-N 3.16Å; S143-G147 PolarHBondContact O-N 2.81Å; S143-T169 VanDerWaalsContact CB-CG2 3.4Å; S143-T169 WeakPolarHBondContact O-CG2 3.47Å; S143-T169 PolarHBondContact O-OG1 3.43Å; S143-T169 WeakPolarHBondContact OG-CG2 3.5Å; S143-M331 VanDerWaalsContact CA-SD 3.51Å; S143-M331 WeakPolarHBondContact CB-SD 3.36Å
144	L	90.3	Very high	89.9	Confident	20 Å²	20	23 Å²	23	11%	0.105	11%	0.109	C	C	.	.	H	α-helix	trans	-62.7	-40.9	174.7	-79.6	168	0	0	0	111.4	A140 V141 F146 G147 R148 I165 K166 L380	A140-L144 WeakPolarHBondContact O-CB 3.33Å; A140-L144 WeakPolarHBondContact O-CG 3.35Å; A140-L144 PolarHBondContact O-N 3.44Å; V141-L144 PolarHBondContact O-N 2.93Å; L144-F146 VanDerWaalsContact C-N 3.34Å; L144-F146 PolarHBondContact O-N 2.78Å; L144-G147 PolarHBondContact O-N 3.01Å; L144-R148 PolarHBondContact O-N 3.48Å; L144-I165 HydrophobicContact CD2-CG2 4.14Å; L144-K166 HydrophobicContact CD2-CG 4.28Å; L144-L380 HydrophobicContact CD1-CD1 4.26Å; L144-L380 HydrophobicContact CD2-CD1 3.42Å; L144-L380 VanDerWaalsContact CD2-CD1 3.42Å; L144-L380 HydrophobicContact CG-CD1 3.56Å
145	A	88.9	Confident	89.9	Confident	4 Å²	4	26.1 Å²	26.1	3%	0.033	12%	0.122	C	C	.	.	H	α-helix	trans	-59.6	-45.5	172.3	0	0	0	0	0	111.2	A60 I64 V141 I142 S143 G147 R148 Y149	A60-A145 HydrophobicContact CB-CB 3.52Å; I64-A145 HydrophobicContact CD1-CB 4.02Å; V141-A145 PolarHBondContact O-N 2.73Å; V141-A145 VanDerWaalsContact O-N 3.17Å; I142-A145 PolarHBondContact O-N 3.09Å; S143-A145 VanDerWaalsContact C-N 3.32Å; S143-A145 PolarHBondContact O-N 3.11Å; A145-G147 PolarHBondContact O-N 2.87Å; A145-R148 PolarHBondContact O-N 3.49Å; A145-Y149 VanDerWaalsContact O-CD2 3.25Å; A145-Y149 WeakPolarHBondContact O-CD2 3.46Å; A145-Y149 PolarHBondContact O-N 2.95Å
146	F	92.9	Very high	89.3	Confident	22 Å²	22	30.3 Å²	30.3	10%	0.096	14%	0.144	C	C	.	.	H	α-helix	trans	-54.2	-50.8	173.1	161.8	-95.8	0	0	0	112	I142 S143 L144 R148 Y149 I150 I168 A324 C327 F328 M331	I142-F146 PolarHBondContact O-N 3.47Å; I142-F146 VanDerWaalsContact O-N 3.1Å; S143-F146 WeakPolarHBondContact O-CA 3.36Å; S143-F146 VanDerWaalsContact O-CB 3.28Å; S143-F146 WeakPolarHBondContact O-CB 3.2Å; S143-F146 PolarHBondContact O-N 3.4Å; S143-F146 VanDerWaalsContact O-N 3.16Å; L144-F146 VanDerWaalsContact C-N 3.34Å; L144-F146 PolarHBondContact O-N 2.78Å; F146-R148 VanDerWaalsContact C-N 3.31Å; F146-R148 PolarHBondContact O-N 3.13Å; F146-Y149 PolarHBondContact O-N 2.91Å; F146-I150 HydrophobicContact CE1-CG2 4.42Å; F146-I150 HydrophobicContact CE2-CB 4.43Å; F146-I150 HydrophobicContact CZ-CB 4.5Å; F146-I150 HydrophobicContact CZ-CG2 4.38Å; F146-I150 WeakPolarHBondContact O-CB 3.48Å; F146-I150 WeakPolarHBondContact O-CG2 3.49Å; F146-I150 PolarHBondContact O-N 3.4Å; F146-I168 HydrophobicContact CE1-CG2 4.41Å; F146-A324 HydrophobicContact CD2-CB 3.97Å; F146-A324 WeakPolarHBondContact CD2-O 3.29Å; F146-A324 HydrophobicContact CE2-CB 4.24Å; F146-C327 HydrophobicContact CB-CB 3.64Å; F146-F328 HydrophobicContact CD2-CB 4.17Å; F146-F328 HydrophobicContact CE2-CB 4.33Å; F146-F328 HydrophobicContact CE2-CD2 4.15Å; F146-F328 HydrophobicContact CZ-CD2 4.44Å; F146-M331 HydrophobicContact CB-CE 3.82Å; F146-M331 HydrophobicContact CD1-CE 4.05Å; F146-M331 HydrophobicContact CD2-CE 4.28Å; F146-M331 HydrophobicContact CG-CE 3.77Å
147	G	92.7	Very high	88.8	Confident	0 Å²	0	39.3 Å²	39.3	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-63.3	-35.1	-178	0	0	0	0	0	113.6	S143 L144 A145 I150 L151 T169	S143-G147 PolarHBondContact O-N 2.81Å; L144-G147 PolarHBondContact O-N 3.01Å; A145-G147 PolarHBondContact O-N 2.87Å; G147-I150 WeakPolarHBondContact O-CG2 3.34Å; G147-L151 WeakPolarHBondContact O-CB 3.22Å; G147-L151 WeakPolarHBondContact O-CG 3.38Å; G147-L151 PolarHBondContact O-N 3.13Å; G147-T169 WeakPolarHBondContact CA-OG1 3.36Å
148	R	89.8	Confident	88.7	Confident	82 Å²	82	43.4 Å²	43.4	31%	0.309	21%	0.214	S	C	.	.	H	α-helix	trans	-68.3	-53.9	175.1	-171.2	174.7	-171.3	136.5	12.9	111.2	L144 A145 F146 I150 L151 E152 I160 I165 N301	L144-R148 PolarHBondContact O-N 3.48Å; A145-R148 PolarHBondContact O-N 3.49Å; F146-R148 VanDerWaalsContact C-N 3.31Å; F146-R148 PolarHBondContact O-N 3.13Å; R148-I150 VanDerWaalsContact C-N 3.34Å; R148-I150 PolarHBondContact O-N 2.75Å; R148-L151 PolarHBondContact O-N 3.36Å; R148-L151 VanDerWaalsContact O-N 3.13Å; R148-E152 PolarHBondContact O-N 2.91Å; R148-I160 HydrophobicContact CG-CD1 4.34Å; R148-I165 HydrophobicContact CB-CD1 4.38Å; R148-I165 HydrophobicContact CB-CG2 4.48Å; R148-I165 HydrophobicContact CG-CD1 4.3Å; R148-N301 PolarHBondContact NH2-ND2 2.91Å
149	Y	89.9	Confident	88.5	Confident	6 Å²	6	51.2 Å²	51.2	2%	0.024	25%	0.249	C	C	.	.	H	α-helix	trans	-66	-31.7	-176.1	-82.6	-76.3	0	0	0	113.6	F63 A145 F146 L151 A302 V305 P320 V323	F63-Y149 HydrophobicContact CB-CE2 4.16Å; F63-Y149 WeakPolarHBondContact CB-OH 3.39Å; F63-Y149 PolarHBondContact O-OH 3.17Å; A145-Y149 VanDerWaalsContact O-CD2 3.25Å; A145-Y149 WeakPolarHBondContact O-CD2 3.46Å; A145-Y149 PolarHBondContact O-N 2.95Å; F146-Y149 PolarHBondContact O-N 2.91Å; Y149-L151 VanDerWaalsContact C-N 3.3Å; Y149-A302 HydrophobicContact CE1-CB 3.83Å; Y149-V305 HydrophobicContact CD1-CG2 4.16Å; Y149-V305 HydrophobicContact CE1-CG2 3.97Å; Y149-P320 HydrophobicContact CD1-CB 4.36Å; Y149-P320 WeakPolarHBondContact O-CB 3.3Å; Y149-V323 HydrophobicContact CD1-CB 3.86Å; Y149-V323 HydrophobicContact CD1-CG1 3.55Å; Y149-V323 HydrophobicContact CD1-CG2 4.48Å; Y149-V323 HydrophobicContact CD2-CG1 3.49Å; Y149-V323 VanDerWaalsContact CD2-CG1 3.49Å; Y149-V323 HydrophobicContact CE1-CB 4.25Å; Y149-V323 HydrophobicContact CE1-CG1 3.73Å; Y149-V323 HydrophobicContact CE1-CG2 4.48Å; Y149-V323 HydrophobicContact CE2-CG1 3.72Å; Y149-V323 HydrophobicContact CG-CB 4.04Å; Y149-V323 HydrophobicContact CG-CG1 3.44Å; Y149-V323 VanDerWaalsContact CG-CG1 3.44Å
150	I	92.7	Very high	88.5	Confident	49 Å²	49	51.6 Å²	51.6	25%	0.251	25%	0.251	S	S	.	.	H	α-helix	trans	-72.6	-26.4	176.7	-162	66.6	0	0	0	112.3	F146 G147 R148 F154 I168 A324	F146-I150 HydrophobicContact CE1-CG2 4.42Å; F146-I150 HydrophobicContact CE2-CB 4.43Å; F146-I150 HydrophobicContact CZ-CB 4.5Å; F146-I150 HydrophobicContact CZ-CG2 4.38Å; F146-I150 WeakPolarHBondContact O-CB 3.48Å; F146-I150 WeakPolarHBondContact O-CG2 3.49Å; F146-I150 PolarHBondContact O-N 3.4Å; G147-I150 WeakPolarHBondContact O-CG2 3.34Å; R148-I150 VanDerWaalsContact C-N 3.34Å; R148-I150 PolarHBondContact O-N 2.75Å; I150-F154 WeakPolarHBondContact O-CE2 3.45Å; I150-I168 HydrophobicContact CG2-CG2 3.47Å; I150-I168 VanDerWaalsContact CG2-CG2 3.47Å; I150-A324 HydrophobicContact CB-CB 3.95Å; I150-A324 HydrophobicContact CD1-CB 3.9Å
151	L	91.9	Very high	88.5	Confident	20 Å²	20	54.9 Å²	54.9	11%	0.105	27%	0.272	C	S	.	.	H	α-helix	trans	-87.2	-25.6	178.9	-75.3	177.2	0	0	0	113.1	G147 R148 Y149 P153 F154 F155 I160 A164 I165 I168	G147-L151 WeakPolarHBondContact O-CB 3.22Å; G147-L151 WeakPolarHBondContact O-CG 3.38Å; G147-L151 PolarHBondContact O-N 3.13Å; R148-L151 PolarHBondContact O-N 3.36Å; R148-L151 VanDerWaalsContact O-N 3.13Å; Y149-L151 VanDerWaalsContact C-N 3.3Å; L151-P153 VanDerWaalsContact C-N 3.34Å; L151-P153 VanDerWaalsContact O-N 3.16Å; L151-F154 WeakPolarHBondContact O-CB 3.29Å; L151-F154 PolarHBondContact O-N 3.33Å; L151-F155 HydrophobicContact CB-CD2 4.41Å; L151-F155 HydrophobicContact CD2-CE2 4.31Å; L151-F155 WeakPolarHBondContact O-CD2 3.4Å; L151-I160 HydrophobicContact CB-CD1 4.02Å; L151-I160 HydrophobicContact CB-CG2 4.1Å; L151-I160 HydrophobicContact CD1-CG2 3.78Å; L151-A164 HydrophobicContact CD1-CB 4.13Å; L151-I165 HydrophobicContact CD1-CG1 4.2Å; L151-I168 HydrophobicContact CD1-CB 4.33Å; L151-I168 HydrophobicContact CD1-CG1 4.12Å; L151-I168 HydrophobicContact CD2-CG1 4.12Å; L151-I168 HydrophobicContact CG-CG1 4.32Å
152	E	87.6	Confident	88.6	Confident	37 Å²	37	60.8 Å²	60.8	17%	0.173	30%	0.3	C	S	.	.	G	3₁₀ helix	trans	-46.3	-46.2	-177.3	-152.9	81.5	-176.6	0	0	114.5	R148 F154 F155 I156 I160 V305 P320	R148-E152 PolarHBondContact O-N 2.91Å; E152-F154 PolarHBondContact O-N 3.29Å; E152-F154 VanDerWaalsContact O-N 3.09Å; E152-F155 CarbonylContact O-C 3.55Å; E152-F155 PolarHBondContact O-N 2.86Å; E152-I156 PolarHBondContact O-N 2.93Å; E152-I160 WeakPolarHBondContact OE2-CD1 3.33Å; E152-V305 HydrophobicContact CG-CG1 4.16Å; E152-V305 HydrophobicContact CG-CG2 4.18Å; E152-P320 HydrophobicContact CB-CB 4.17Å
153	P	86.8	Confident	88.7	Confident	29 Å²	29	64.9 Å²	64.9	19%	0.188	32%	0.321	C	S	.	.	G	3₁₀ helix	trans	-61.2	-22.9	179.7	-24.4	36.3	0	0	0	114.6	L151 I156 L317 P320	L151-P153 VanDerWaalsContact C-N 3.34Å; L151-P153 VanDerWaalsContact O-N 3.16Å; P153-I156 WeakPolarHBondContact O-CD1 3.4Å; P153-I156 WeakPolarHBondContact O-CG1 3.26Å; P153-L317 HydrophobicContact CB-CD2 4.35Å; P153-P320 HydrophobicContact CG-CB 4.08Å; P153-P320 HydrophobicContact CG-CG 3.65Å
154	F	88.6	Confident	88.8	Confident	161 Å²	161	66.3 Å²	66.3	71%	0.706	33%	0.333	S	S	*	.	G	3₁₀ helix	trans	-90.4	-11.6	-178.9	-56.9	-79.7	0	0	0	112.7	I150 L151 E152	I150-F154 WeakPolarHBondContact O-CE2 3.45Å; L151-F154 WeakPolarHBondContact O-CB 3.29Å; L151-F154 PolarHBondContact O-N 3.33Å; E152-F154 PolarHBondContact O-N 3.29Å; E152-F154 VanDerWaalsContact O-N 3.09Å
155	F	87.8	Confident	88.9	Confident	66 Å²	66	66.3 Å²	66.3	29%	0.289	33%	0.333	S	S	.	.			trans	-130.5	33	-173.1	-70.8	-92	0	0	0	112.1	L151 E152 Q157 C158 I160	L151-F155 HydrophobicContact CB-CD2 4.41Å; L151-F155 HydrophobicContact CD2-CE2 4.31Å; L151-F155 WeakPolarHBondContact O-CD2 3.4Å; E152-F155 CarbonylContact O-C 3.55Å; E152-F155 PolarHBondContact O-N 2.86Å; F155-Q157 PolarHBondContact O-N 3.27Å; F155-C158 HydrophobicContact CD1-CB 4.23Å; F155-C158 PolarHBondContact O-N 3.5Å; F155-I160 HydrophobicContact CB-CD1 4.45Å; F155-I160 HydrophobicContact CB-CG1 3.54Å; F155-I160 HydrophobicContact CD2-CG1 4.09Å; F155-I160 HydrophobicContact CD2-CG2 4.36Å; F155-I160 HydrophobicContact CG-CB 4.48Å; F155-I160 HydrophobicContact CG-CG1 3.82Å
156	I	77.1	Confident	89.1	Confident	95 Å²	95	67.6 Å²	67.6	49%	0.487	34%	0.338	S	S	.	.	T	Hydrogen-bonded Turn	trans	-52.9	-34.2	-175	-58.8	168	0	0	0	113.1	E152 P153 L317	E152-I156 PolarHBondContact O-N 2.93Å; P153-I156 WeakPolarHBondContact O-CD1 3.4Å; P153-I156 WeakPolarHBondContact O-CG1 3.26Å; I156-L317 HydrophobicContact CD1-CD2 3.65Å
157	Q	79.9	Confident	89.3	Confident	189 Å²	189	71 Å²	71	88%	0.883	36%	0.356	S	S	*	.	T	Hydrogen-bonded Turn	trans	-106.7	2.5	-177	-63.5	-178	-13.5	0	0	113.8	F155	F155-Q157 PolarHBondContact O-N 3.27Å
158	C	85.5	Confident	89.4	Confident	86 Å²	86	74.1 Å²	74.1	58%	0.581	37%	0.373	S	S	*	.	S	Bend	trans	-135.4	150.8	-170.8	-65.7	0	0	0	0	111.1	F155 I160	F155-C158 HydrophobicContact CD1-CB 4.23Å; F155-C158 PolarHBondContact O-N 3.5Å; C158-I160 PolarHBondContact O-N 3.21Å
159	E	85.8	Confident	89.7	Confident	172 Å²	172	70.2 Å²	70.2	80%	0.804	36%	0.358	S	S	*	.	P	Polyproline II helix	trans	-70.5	133.3	170.8	-166.7	169.2	-167.4	0	0	110.3	P161	E159-P161 WeakPolarHBondContact O-CD 2.95Å
160	I	88.9	Confident	90	Very high	18 Å²	18	70.6 Å²	70.6	9%	0.092	36%	0.362	C	S	.	.	P	Polyproline II helix	trans	-74.3	125.1	179.2	-54.6	165.8	0	0	0	108.6	R148 L151 E152 F155 C158 E162 I165	R148-I160 HydrophobicContact CG-CD1 4.34Å; L151-I160 HydrophobicContact CB-CD1 4.02Å; L151-I160 HydrophobicContact CB-CG2 4.1Å; L151-I160 HydrophobicContact CD1-CG2 3.78Å; E152-I160 WeakPolarHBondContact OE2-CD1 3.33Å; F155-I160 HydrophobicContact CB-CD1 4.45Å; F155-I160 HydrophobicContact CB-CG1 3.54Å; F155-I160 HydrophobicContact CD2-CG1 4.09Å; F155-I160 HydrophobicContact CD2-CG2 4.36Å; F155-I160 HydrophobicContact CG-CB 4.48Å; F155-I160 HydrophobicContact CG-CG1 3.82Å; C158-I160 PolarHBondContact O-N 3.21Å; I160-E162 PolarHBondContact O-N 3.14Å; I160-I165 HydrophobicContact CB-CD1 4.13Å; I160-I165 HydrophobicContact CB-CG1 4.26Å; I160-I165 HydrophobicContact CG2-CD1 3.96Å; I160-I165 HydrophobicContact CG2-CG1 3.52Å
161	P	92.3	Very high	90.1	Very high	68 Å²	68	72.6 Å²	72.6	44%	0.442	38%	0.377	S	S	.	.	P	Polyproline II helix	trans	-59.5	131.5	175.8	-23.2	33.4	0	0	0	111.8	E159 L163 A164 I165	E159-P161 WeakPolarHBondContact O-CD 2.95Å; P161-L163 PolarHBondContact O-N 3.49Å; P161-A164 HydrophobicContact CB-CB 4.24Å; P161-A164 WeakPolarHBondContact O-CB 3.31Å; P161-A164 PolarHBondContact O-N 3.01Å; P161-I165 PolarHBondContact O-N 3.4Å
162	E	89.7	Confident	90.3	Very high	125 Å²	125	72 Å²	72	58%	0.584	37%	0.374	S	S	*	.	H	α-helix	trans	-56.9	-38.9	-177.4	-167.9	-167.9	156.6	0	0	112.4	I160 A164 I165 K166	I160-E162 PolarHBondContact O-N 3.14Å; E162-A164 VanDerWaalsContact C-N 3.31Å; E162-A164 PolarHBondContact O-N 3Å; E162-I165 WeakPolarHBondContact O-CB 3.46Å; E162-I165 PolarHBondContact O-N 2.96Å; E162-K166 PolarHBondContact O-N 3.47Å; E162-K166 WeakPolarHBondContact OE1-CE 3.48Å; E162-K166 IonicContact OE1-NZ 3.58Å; E162-K166 PolarHBondContact OE1-NZ 3.41Å
163	L	92.3	Very high	90.6	Very high	114 Å²	114	70.2 Å²	70.2	60%	0.597	37%	0.366	S	S	*	.	H	α-helix	trans	-62.2	-38	176.9	-174	64.2	0	0	0	112	P161 K166 L167	P161-L163 PolarHBondContact O-N 3.49Å; L163-K166 PolarHBondContact O-N 3.13Å; L163-L167 HydrophobicContact CD1-CD1 4.47Å; L163-L167 HydrophobicContact CD1-CG 4.36Å; L163-L167 HydrophobicContact CG-CD1 4.07Å; L163-L167 HydrophobicContact CG-CG 4.38Å; L163-L167 WeakPolarHBondContact O-CB 3.39Å; L163-L167 VanDerWaalsContact O-CG 3.26Å; L163-L167 WeakPolarHBondContact O-CG 3.12Å; L163-L167 PolarHBondContact O-N 2.92Å
164	A	94.1	Very high	91	Very high	29 Å²	29	71.3 Å²	71.3	24%	0.24	37%	0.372	C	S	.	.	H	α-helix	trans	-65.5	-42.2	177.3	0	0	0	0	0	111.1	L151 P161 E162 L167 I168	L151-A164 HydrophobicContact CD1-CB 4.13Å; P161-A164 HydrophobicContact CB-CB 4.24Å; P161-A164 WeakPolarHBondContact O-CB 3.31Å; P161-A164 PolarHBondContact O-N 3.01Å; E162-A164 VanDerWaalsContact C-N 3.31Å; E162-A164 PolarHBondContact O-N 3Å; A164-L167 PolarHBondContact O-N 3.14Å; A164-I168 WeakPolarHBondContact O-CB 3.36Å; A164-I168 WeakPolarHBondContact O-CG1 3.26Å; A164-I168 PolarHBondContact O-N 3.44Å
165	I	92.3	Very high	91.2	Very high	21 Å²	21	66.8 Å²	66.8	11%	0.108	36%	0.358	C	S	.	.	H	α-helix	trans	-58	-51.2	173.5	-61.4	174.9	0	0	0	109.8	L144 R148 L151 I160 P161 E162 L167 T169	L144-I165 HydrophobicContact CD2-CG2 4.14Å; R148-I165 HydrophobicContact CB-CD1 4.38Å; R148-I165 HydrophobicContact CB-CG2 4.48Å; R148-I165 HydrophobicContact CG-CD1 4.3Å; L151-I165 HydrophobicContact CD1-CG1 4.2Å; I160-I165 HydrophobicContact CB-CD1 4.13Å; I160-I165 HydrophobicContact CB-CG1 4.26Å; I160-I165 HydrophobicContact CG2-CD1 3.96Å; I160-I165 HydrophobicContact CG2-CG1 3.52Å; P161-I165 PolarHBondContact O-N 3.4Å; E162-I165 WeakPolarHBondContact O-CB 3.46Å; E162-I165 PolarHBondContact O-N 2.96Å; I165-L167 PolarHBondContact O-N 3.39Å; I165-T169 WeakPolarHBondContact O-CB 3.46Å; I165-T169 PolarHBondContact O-N 3.16Å; I165-T169 PolarHBondContact O-OG1 3.05Å
166	K	93.4	Very high	91.4	Very high	30 Å²	30	63.7 Å²	63.7	13%	0.13	34%	0.344	C	S	.	.	H	α-helix	trans	-61.6	-42.2	-178.6	-74.4	179.8	174.3	171.4	0	112.4	L144 E162 L163 T169 A170 F381	L144-K166 HydrophobicContact CD2-CG 4.28Å; E162-K166 PolarHBondContact O-N 3.47Å; E162-K166 WeakPolarHBondContact OE1-CE 3.48Å; E162-K166 IonicContact OE1-NZ 3.58Å; E162-K166 PolarHBondContact OE1-NZ 3.41Å; L163-K166 PolarHBondContact O-N 3.13Å; K166-T169 WeakPolarHBondContact O-CB 3.48Å; K166-T169 PolarHBondContact O-N 2.95Å; K166-A170 WeakPolarHBondContact O-CB 3.32Å; K166-A170 PolarHBondContact O-N 2.87Å; K166-F381 HydrophobicContact CB-CD1 4.32Å; K166-F381 HydrophobicContact CB-CE1 3.92Å; K166-F381 HydrophobicContact CD-CD1 4.06Å; K166-F381 HydrophobicContact CD-CE1 4.48Å; K166-F381 PolarHBondContact NZ-O 3.33Å
167	L	95.6	Very high	92	Very high	94 Å²	94	59.5 Å²	59.5	49%	0.492	32%	0.323	S	S	.	.	H	α-helix	trans	-67.3	-47.6	179.3	-70.7	175	0	0	0	112.5	L163 A164 I165 T169 A170 V171	L163-L167 HydrophobicContact CD1-CD1 4.47Å; L163-L167 HydrophobicContact CD1-CG 4.36Å; L163-L167 HydrophobicContact CG-CD1 4.07Å; L163-L167 HydrophobicContact CG-CG 4.38Å; L163-L167 WeakPolarHBondContact O-CB 3.39Å; L163-L167 VanDerWaalsContact O-CG 3.26Å; L163-L167 WeakPolarHBondContact O-CG 3.12Å; L163-L167 PolarHBondContact O-N 2.92Å; A164-L167 PolarHBondContact O-N 3.14Å; I165-L167 PolarHBondContact O-N 3.39Å; L167-T169 VanDerWaalsContact C-N 3.29Å; L167-T169 PolarHBondContact O-N 3.38Å; L167-A170 WeakPolarHBondContact O-CB 3.25Å; L167-A170 PolarHBondContact O-N 2.78Å; L167-V171 WeakPolarHBondContact O-CG2 3.45Å; L167-V171 PolarHBondContact O-N 3.11Å
168	I	95.9	Very high	92.4	Very high	66 Å²	66	54 Å²	54	34%	0.338	30%	0.302	S	S	.	.	H	α-helix	trans	-64.9	-37.7	176.5	-69.4	-64.5	0	0	0	111.2	F146 I150 L151 A164 V171 G172	F146-I168 HydrophobicContact CE1-CG2 4.41Å; I150-I168 HydrophobicContact CG2-CG2 3.47Å; I150-I168 VanDerWaalsContact CG2-CG2 3.47Å; L151-I168 HydrophobicContact CD1-CB 4.33Å; L151-I168 HydrophobicContact CD1-CG1 4.12Å; L151-I168 HydrophobicContact CD2-CG1 4.12Å; L151-I168 HydrophobicContact CG-CG1 4.32Å; A164-I168 WeakPolarHBondContact O-CB 3.36Å; A164-I168 WeakPolarHBondContact O-CG1 3.26Å; A164-I168 PolarHBondContact O-N 3.44Å; I168-V171 PolarHBondContact O-N 3.35Å; I168-G172 PolarHBondContact O-N 3.19Å
169	T	95.2	Very high	92.5	Very high	0 Å²	0	52.1 Å²	52.1	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-58.9	-47	172.6	-62.8	0	0	0	0	111.3	S143 G147 I165 K166 L167 V171 G172 L173 L380	S143-T169 VanDerWaalsContact CB-CG2 3.4Å; S143-T169 WeakPolarHBondContact O-CG2 3.47Å; S143-T169 PolarHBondContact O-OG1 3.43Å; S143-T169 WeakPolarHBondContact OG-CG2 3.5Å; G147-T169 WeakPolarHBondContact CA-OG1 3.36Å; I165-T169 WeakPolarHBondContact O-CB 3.46Å; I165-T169 PolarHBondContact O-N 3.16Å; I165-T169 PolarHBondContact O-OG1 3.05Å; K166-T169 WeakPolarHBondContact O-CB 3.48Å; K166-T169 PolarHBondContact O-N 2.95Å; L167-T169 VanDerWaalsContact C-N 3.29Å; L167-T169 PolarHBondContact O-N 3.38Å; T169-V171 VanDerWaalsContact C-N 3.33Å; T169-V171 PolarHBondContact O-N 3.43Å; T169-G172 PolarHBondContact O-N 3.49Å; T169-L173 VanDerWaalsContact O-CB 3.29Å; T169-L173 WeakPolarHBondContact O-CB 3.29Å; T169-L173 PolarHBondContact O-N 3.19Å; T169-L380 HydrophobicContact CG2-CD1 3.4Å; T169-L380 VanDerWaalsContact CG2-CD1 3.4Å; T169-L380 HydrophobicContact CG2-CD2 3.84Å; T169-L380 HydrophobicContact CG2-CG 4.28Å
170	A	95.9	Very high	92.5	Very high	14 Å²	14	44.4 Å²	44.4	12%	0.116	25%	0.25	C	S	.	.	H	α-helix	trans	-60	-42.8	178.4	0	0	0	0	0	111.5	K166 L167 T174 M377 L380 F381	K166-A170 WeakPolarHBondContact O-CB 3.32Å; K166-A170 PolarHBondContact O-N 2.87Å; L167-A170 WeakPolarHBondContact O-CB 3.25Å; L167-A170 PolarHBondContact O-N 2.78Å; A170-T174 WeakPolarHBondContact O-CB 3.47Å; A170-T174 PolarHBondContact O-N 2.9Å; A170-T174 PolarHBondContact O-OG1 3.36Å; A170-M377 HydrophobicContact CB-CE 3.75Å; A170-M377 HydrophobicContact CB-SD 3.88Å; A170-M377 WeakPolarHBondContact O-CE 3.13Å; A170-L380 HydrophobicContact CB-CD2 3.95Å; A170-F381 HydrophobicContact CB-CZ 4.42Å
171	V	96.4	Very high	92.3	Very high	91 Å²	91	44.3 Å²	44.3	55%	0.552	25%	0.251	S	S	*	.	H	α-helix	trans	-61.5	-51.5	174.7	174.4	0	0	0	0	110.7	L167 I168 T169 L173 T174 V175	L167-V171 WeakPolarHBondContact O-CG2 3.45Å; L167-V171 PolarHBondContact O-N 3.11Å; I168-V171 PolarHBondContact O-N 3.35Å; T169-V171 VanDerWaalsContact C-N 3.33Å; T169-V171 PolarHBondContact O-N 3.43Å; V171-L173 PolarHBondContact O-N 3.19Å; V171-T174 WeakPolarHBondContact O-CB 3.41Å; V171-T174 PolarHBondContact O-N 3.01Å; V171-T174 VanDerWaalsContact O-N 3.17Å; V171-V175 WeakPolarHBondContact O-CG2 3.3Å; V171-V175 PolarHBondContact O-N 3.28Å
172	G	94.9	Very high	92	Very high	6 Å²	6	46 Å²	46	6%	0.062	25%	0.254	C	S	.	.	H	α-helix	trans	-59.3	-44.7	180	0	0	0	0	0	112.9	I168 T169 T174 V175 V176	I168-G172 PolarHBondContact O-N 3.19Å; T169-G172 PolarHBondContact O-N 3.49Å; G172-T174 PolarHBondContact O-N 3.39Å; G172-V175 PolarHBondContact O-N 3.48Å; G172-V176 WeakPolarHBondContact O-CG2 3.25Å; G172-V176 PolarHBondContact O-N 3.04Å
173	L	94.1	Very high	91.5	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-59.6	-45.3	174.9	178.2	63.3	0	0	0	111.6	T139 T169 V171 V175 V176 M177 T376 M377	T139-L173 HydrophobicContact CG2-CD1 3.62Å; T169-L173 VanDerWaalsContact O-CB 3.29Å; T169-L173 WeakPolarHBondContact O-CB 3.29Å; T169-L173 PolarHBondContact O-N 3.19Å; V171-L173 PolarHBondContact O-N 3.19Å; L173-V175 VanDerWaalsContact C-N 3.33Å; L173-V175 PolarHBondContact O-N 2.98Å; L173-V176 PolarHBondContact O-N 3Å; L173-M177 HydrophobicContact CD1-CE 3.81Å; L173-M177 VanDerWaalsContact O-CG 3.29Å; L173-M177 WeakPolarHBondContact O-CG 3.31Å; L173-M177 PolarHBondContact O-N 2.8Å; L173-T376 HydrophobicContact CD1-CG2 4.15Å; L173-T376 HydrophobicContact CD2-CG2 3.47Å; L173-T376 VanDerWaalsContact CD2-CG2 3.47Å; L173-T376 HydrophobicContact CG-CG2 4.45Å; L173-M377 HydrophobicContact CD2-CE 4.03Å; L173-M377 HydrophobicContact CD2-SD 4.28Å
174	T	94.5	Very high	90.7	Very high	52 Å²	52	37.4 Å²	37.4	32%	0.319	22%	0.216	S	C	.	.	H	α-helix	trans	-61.4	-43.3	178.4	-55.7	0	0	0	0	111	A170 V171 G172 V176 M177 V178 H373 M377	A170-T174 WeakPolarHBondContact O-CB 3.47Å; A170-T174 PolarHBondContact O-N 2.9Å; A170-T174 PolarHBondContact O-OG1 3.36Å; V171-T174 WeakPolarHBondContact O-CB 3.41Å; V171-T174 PolarHBondContact O-N 3.01Å; V171-T174 VanDerWaalsContact O-N 3.17Å; G172-T174 PolarHBondContact O-N 3.39Å; T174-V176 PolarHBondContact O-N 3.25Å; T174-M177 PolarHBondContact O-N 2.84Å; T174-V178 HydrophobicContact CG2-CG2 4.46Å; T174-V178 WeakPolarHBondContact O-CG2 3.25Å; T174-V178 PolarHBondContact O-N 3.38Å; T174-H373 PolarHBondContact OG1-CE1 2.81Å; T174-M377 WeakPolarHBondContact OG1-CE 3.41Å
175	V	93.4	Very high	90	Very high	67 Å²	67	38.4 Å²	38.4	41%	0.406	22%	0.221	S	C	.	.	H	α-helix	trans	-59.6	-45.9	175.7	172.2	0	0	0	0	111	V171 G172 L173 M177 V178 L179 F328	V171-V175 WeakPolarHBondContact O-CG2 3.3Å; V171-V175 PolarHBondContact O-N 3.28Å; G172-V175 PolarHBondContact O-N 3.48Å; L173-V175 VanDerWaalsContact C-N 3.33Å; L173-V175 PolarHBondContact O-N 2.98Å; V175-M177 VanDerWaalsContact C-N 3.32Å; V175-M177 PolarHBondContact O-N 2.73Å; V175-V178 PolarHBondContact O-N 3.25Å; V175-L179 HydrophobicContact CG1-CD1 3.94Å; V175-L179 HydrophobicContact CG1-CG 4.32Å; V175-L179 WeakPolarHBondContact O-CB 3.31Å; V175-L179 VanDerWaalsContact O-CG 3.29Å; V175-L179 WeakPolarHBondContact O-CG 3.21Å; V175-L179 PolarHBondContact O-N 3.47Å; V175-F328 HydrophobicContact CG1-CE2 4.25Å; V175-F328 HydrophobicContact CG1-CZ 4.09Å
176	V	91.5	Very high	89.5	Confident	0 Å²	0	44.9 Å²	44.9	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-59.1	-44.2	176.5	173.2	0	0	0	0	111.4	G172 L173 T174 L179 N180 F328 M331 N332 V335	G172-V176 WeakPolarHBondContact O-CG2 3.25Å; G172-V176 PolarHBondContact O-N 3.04Å; L173-V176 PolarHBondContact O-N 3Å; T174-V176 PolarHBondContact O-N 3.25Å; V176-L179 PolarHBondContact O-N 3.05Å; V176-N180 PolarHBondContact O-N 3.41Å; V176-N180 PolarHBondContact O-ND2 2.72Å; V176-F328 HydrophobicContact CG2-CD1 4.3Å; V176-F328 HydrophobicContact CG2-CD2 3.77Å; V176-F328 HydrophobicContact CG2-CE1 3.98Å; V176-F328 HydrophobicContact CG2-CE2 3.39Å; V176-F328 HydrophobicContact CG2-CG 4.22Å; V176-F328 HydrophobicContact CG2-CZ 3.51Å; V176-M331 HydrophobicContact CG1-CB 4.08Å; V176-M331 HydrophobicContact CG2-CB 4.11Å; V176-M331 HydrophobicContact CG2-CE 4.2Å; V176-N332 HydrophobicContact CG1-CB 4.18Å; V176-V335 HydrophobicContact CG1-CG2 4.22Å
177	M	89.8	Confident	89	Confident	8 Å²	8	43.6 Å²	43.6	4%	0.039	24%	0.239	C	C	.	.	H	α-helix	trans	-64.2	-42.2	179.1	-66.5	-68.5	-178.6	0	0	111.6	L173 T174 V175 N180 S181 V335 V369 L372 H373	L173-M177 HydrophobicContact CD1-CE 3.81Å; L173-M177 VanDerWaalsContact O-CG 3.29Å; L173-M177 WeakPolarHBondContact O-CG 3.31Å; L173-M177 PolarHBondContact O-N 2.8Å; T174-M177 PolarHBondContact O-N 2.84Å; V175-M177 VanDerWaalsContact C-N 3.32Å; V175-M177 PolarHBondContact O-N 2.73Å; M177-N180 PolarHBondContact O-N 2.9Å; M177-S181 VanDerWaalsContact O-CB 3.28Å; M177-S181 WeakPolarHBondContact O-CB 3.33Å; M177-S181 PolarHBondContact O-N 2.73Å; M177-S181 PolarHBondContact O-OG 2.69Å; M177-V335 HydrophobicContact CE-CG2 3.65Å; M177-V335 HydrophobicContact SD-CB 4.5Å; M177-V335 HydrophobicContact SD-CG1 3.83Å; M177-V335 HydrophobicContact SD-CG2 3.76Å; M177-V369 HydrophobicContact CB-CG1 4.17Å; M177-V369 HydrophobicContact SD-CG1 3.64Å; M177-L372 HydrophobicContact CE-CB 4.5Å; M177-L372 HydrophobicContact CE-CD2 4.02Å; M177-L372 HydrophobicContact CE-CG 4.1Å; M177-H373 HydrophobicContact CG-CB 4.34Å
178	V	89.8	Confident	88.3	Confident	72 Å²	72	40.7 Å²	40.7	44%	0.436	23%	0.229	S	C	.	.	H	α-helix	trans	-63.6	-45.2	176.2	171.1	0	0	0	0	111.1	T174 V175 N180 S181 M182	T174-V178 HydrophobicContact CG2-CG2 4.46Å; T174-V178 WeakPolarHBondContact O-CG2 3.25Å; T174-V178 PolarHBondContact O-N 3.38Å; V175-V178 PolarHBondContact O-N 3.25Å; V178-N180 PolarHBondContact O-N 2.69Å; V178-S181 CarbonylContact O-C 3.6Å; V178-S181 WeakPolarHBondContact O-CA 3.5Å; V178-S181 WeakPolarHBondContact O-CB 3.28Å; V178-S181 PolarHBondContact O-N 2.84Å; V178-S181 VanDerWaalsContact O-N 3.1Å; V178-M182 HydrophobicContact CG1-CG 4.17Å; V178-M182 HydrophobicContact CG1-SD 3.73Å; V178-M182 VanDerWaalsContact O-CG 3.3Å; V178-M182 WeakPolarHBondContact O-CG 3.49Å; V178-M182 PolarHBondContact O-N 2.93Å
179	L	87.8	Confident	87.8	Confident	47 Å²	47	44.8 Å²	44.8	25%	0.246	24%	0.24	C	C	.	.	H	α-helix	trans	-59.8	-44.4	178.3	-72.4	172.2	0	0	0	112.1	V175 V176 S181 M182 S183 I190 F328	V175-L179 HydrophobicContact CG1-CD1 3.94Å; V175-L179 HydrophobicContact CG1-CG 4.32Å; V175-L179 WeakPolarHBondContact O-CB 3.31Å; V175-L179 VanDerWaalsContact O-CG 3.29Å; V175-L179 WeakPolarHBondContact O-CG 3.21Å; V175-L179 PolarHBondContact O-N 3.47Å; V176-L179 PolarHBondContact O-N 3.05Å; L179-S181 VanDerWaalsContact C-N 3.26Å; L179-S181 PolarHBondContact O-N 3.46Å; L179-M182 PolarHBondContact O-N 3.26Å; L179-S183 PolarHBondContact O-N 3.3Å; L179-I190 HydrophobicContact CD1-CD1 4.29Å; L179-I190 HydrophobicContact CD2-CD1 4.2Å; L179-F328 HydrophobicContact CD1-CE1 4.25Å; L179-F328 HydrophobicContact CD1-CZ 3.89Å
180	N	85.6	Confident	87.3	Confident	10 Å²	10	46.9 Å²	46.9	5%	0.053	25%	0.251	C	S	.	.	H	α-helix	trans	-67.8	-28.2	176.8	-79	-76.6	0	0	0	112.9	V176 M177 V178 S187 N332 V335	V176-N180 PolarHBondContact O-N 3.41Å; V176-N180 PolarHBondContact O-ND2 2.72Å; M177-N180 PolarHBondContact O-N 2.9Å; V178-N180 PolarHBondContact O-N 2.69Å; N180-S187 PolarHBondContact OD1-OG 2.86Å; N180-N332 PolarHBondContact ND2-OD1 2.85Å; N180-V335 HydrophobicContact CB-CG1 3.86Å
181	S	84.7	Confident	86.9	Confident	16 Å²	16	46.6 Å²	46.6	11%	0.112	25%	0.247	C	C	.	.	H	α-helix	trans	-76	-31.4	175.9	-65.1	0	0	0	0	113.1	M177 V178 L179 T364 L366	M177-S181 VanDerWaalsContact O-CB 3.28Å; M177-S181 WeakPolarHBondContact O-CB 3.33Å; M177-S181 PolarHBondContact O-N 2.73Å; M177-S181 PolarHBondContact O-OG 2.69Å; V178-S181 CarbonylContact O-C 3.6Å; V178-S181 WeakPolarHBondContact O-CA 3.5Å; V178-S181 WeakPolarHBondContact O-CB 3.28Å; V178-S181 PolarHBondContact O-N 2.84Å; V178-S181 VanDerWaalsContact O-N 3.1Å; L179-S181 VanDerWaalsContact C-N 3.26Å; L179-S181 PolarHBondContact O-N 3.46Å; S181-T364 PolarHBondContact O-OG1 3.01Å; S181-L366 VanDerWaalsContact CB-CD1 3.45Å; S181-L366 WeakPolarHBondContact OG-CD1 3.28Å
182	M	85	Confident	86.4	Confident	104 Å²	104	45.7 Å²	45.7	51%	0.512	24%	0.239	S	C	.	.	H	α-helix	trans	-79.3	-47	-174.8	-76.3	179.5	73.4	0	0	113.9	V178 L179 K362	V178-M182 HydrophobicContact CG1-CG 4.17Å; V178-M182 HydrophobicContact CG1-SD 3.73Å; V178-M182 VanDerWaalsContact O-CG 3.3Å; V178-M182 WeakPolarHBondContact O-CG 3.49Å; V178-M182 PolarHBondContact O-N 2.93Å; L179-M182 PolarHBondContact O-N 3.26Å; M182-K362 WeakPolarHBondContact O-CB 3.45Å; M182-K362 WeakPolarHBondContact O-CD 3.14Å; M182-K362 WeakPolarHBondContact O-CG 3.45Å
183	S	80.3	Confident	86.1	Confident	27 Å²	27	51.4 Å²	51.4	19%	0.189	26%	0.262	C	S	.	.			trans	-162.6	124.1	179.6	-179	0	0	0	0	112.7	L179 S185 W186 S187	L179-S183 PolarHBondContact O-N 3.3Å; S183-S185 VanDerWaalsContact C-N 3.28Å; S183-S185 PolarHBondContact O-N 3.38Å; S183-S185 PolarHBondContact OG-N 3.01Å; S183-W186 PolarHBondContact O-N 3.16Å; S183-S187 PolarHBondContact O-N 2.9Å
184	V	75	Confident	86	Confident	31 Å²	31	51.7 Å²	51.7	19%	0.188	26%	0.263	C	S	.	.	H	α-helix	trans	-56.6	-41.6	172.5	163.8	0	0	0	0	111.8	S187 A188 F336 T364	V184-S187 PolarHBondContact O-N 3.39Å; V184-A188 WeakPolarHBondContact O-CB 3.35Å; V184-A188 PolarHBondContact O-N 2.85Å; V184-F336 HydrophobicContact CG1-CE2 3.9Å; V184-F336 HydrophobicContact CG1-CZ 4.41Å; V184-T364 HydrophobicContact CG2-CG2 3.82Å
185	S	79.4	Confident	85.6	Confident	50 Å²	50	49.6 Å²	49.6	35%	0.35	25%	0.251	S	S	.	.	H	α-helix	trans	-68.4	-39.8	-176.5	-59.1	0	0	0	0	112.1	S183 R189	S183-S185 VanDerWaalsContact C-N 3.28Å; S183-S185 PolarHBondContact O-N 3.38Å; S183-S185 PolarHBondContact OG-N 3.01Å; S185-R189 WeakPolarHBondContact O-CG 3.22Å; S185-R189 PolarHBondContact O-N 3.23Å; S185-R189 VanDerWaalsContact O-N 3.07Å
186	W	82	Confident	85.4	Confident	158 Å²	158	53.1 Å²	53.1	60%	0.598	26%	0.261	S	S	*	.	H	α-helix	trans	-69	-44.6	175.4	-78.4	106.4	0	0	0	111.7	S183 A188 R189 I190	S183-W186 PolarHBondContact O-N 3.16Å; W186-A188 VanDerWaalsContact C-N 3.27Å; W186-A188 PolarHBondContact O-N 2.99Å; W186-R189 PolarHBondContact O-N 3.02Å; W186-R189 VanDerWaalsContact O-N 3.15Å; W186-I190 WeakPolarHBondContact O-CB 3.38Å; W186-I190 WeakPolarHBondContact O-CG1 3.32Å; W186-I190 PolarHBondContact O-N 3.44Å
187	S	82.6	Confident	85.3	Confident	2 Å²	2	53.5 Å²	53.5	1%	0.014	26%	0.263	C	S	.	.	H	α-helix	trans	-55.2	-43.2	174.2	174.1	0	0	0	0	111.6	N180 S183 V184 I190 Q191 N332	N180-S187 PolarHBondContact OD1-OG 2.86Å; S183-S187 PolarHBondContact O-N 2.9Å; V184-S187 PolarHBondContact O-N 3.39Å; S187-I190 PolarHBondContact O-N 3.48Å; S187-Q191 WeakPolarHBondContact O-CB 3.2Å; S187-Q191 PolarHBondContact O-N 2.94Å; S187-N332 PolarHBondContact O-ND2 3.43Å; S187-N332 PolarHBondContact OG-ND2 3.39Å; S187-N332 PolarHBondContact OG-OD1 3.4Å; S187-N332 VanDerWaalsContact OG-OD1 3.08Å
188	A	79.9	Confident	85.2	Confident	33 Å²	33	53.1 Å²	53.1	27%	0.273	26%	0.261	S	S	.	.	H	α-helix	trans	-65.9	-40.5	176.5	0	0	0	0	0	113.5	V184 W186 Q191 I192	V184-A188 WeakPolarHBondContact O-CB 3.35Å; V184-A188 PolarHBondContact O-N 2.85Å; W186-A188 VanDerWaalsContact C-N 3.27Å; W186-A188 PolarHBondContact O-N 2.99Å; A188-Q191 WeakPolarHBondContact O-CB 3.21Å; A188-Q191 PolarHBondContact O-N 3.49Å; A188-I192 WeakPolarHBondContact O-CG1 3.45Å; A188-I192 PolarHBondContact O-N 3.04Å; A188-I192 VanDerWaalsContact O-N 3.17Å
189	R	85.1	Confident	85.2	Confident	152 Å²	152	52.4 Å²	52.4	57%	0.574	25%	0.254	S	S	*	.	H	α-helix	trans	-65.6	-44	176.1	-72.7	174.5	-175.2	176	-0	111.7	S185 W186 Q191 I192 F193	S185-R189 WeakPolarHBondContact O-CG 3.22Å; S185-R189 PolarHBondContact O-N 3.23Å; S185-R189 VanDerWaalsContact O-N 3.07Å; W186-R189 PolarHBondContact O-N 3.02Å; W186-R189 VanDerWaalsContact O-N 3.15Å; R189-Q191 VanDerWaalsContact C-N 3.29Å; R189-Q191 PolarHBondContact O-N 3.33Å; R189-I192 PolarHBondContact O-N 3.25Å; R189-F193 PolarHBondContact O-N 2.97Å; R189-F193 VanDerWaalsContact O-N 3.15Å
190	I	86.4	Confident	85.3	Confident	44 Å²	44	51.9 Å²	51.9	23%	0.226	25%	0.253	C	S	.	.	H	α-helix	trans	-60.1	-41.9	174.5	-71.5	170.2	0	0	0	109.9	L179 W186 S187 I192 F193 L194	L179-I190 HydrophobicContact CD1-CD1 4.29Å; L179-I190 HydrophobicContact CD2-CD1 4.2Å; W186-I190 WeakPolarHBondContact O-CB 3.38Å; W186-I190 WeakPolarHBondContact O-CG1 3.32Å; W186-I190 PolarHBondContact O-N 3.44Å; S187-I190 PolarHBondContact O-N 3.48Å; I190-I192 VanDerWaalsContact C-N 3.32Å; I190-I192 PolarHBondContact O-N 3.23Å; I190-F193 PolarHBondContact O-N 3.44Å; I190-L194 HydrophobicContact CG2-CD1 3.48Å; I190-L194 VanDerWaalsContact CG2-CD1 3.48Å; I190-L194 HydrophobicContact CG2-CG 4.06Å; I190-L194 WeakPolarHBondContact O-CB 3.41Å; I190-L194 VanDerWaalsContact O-CG 3.23Å; I190-L194 WeakPolarHBondContact O-CG 3.35Å; I190-L194 PolarHBondContact O-N 3.4Å
191	Q	86.3	Confident	85.4	Confident	8 Å²	8	51.5 Å²	51.5	4%	0.037	25%	0.252	C	S	.	.	H	α-helix	trans	-58.2	-42.5	176.4	-169.5	65.2	20.6	0	0	112.7	G55 S187 A188 R189 L194 T195 G329 N332	G55-Q191 PolarHBondContact O-NE2 2.97Å; S187-Q191 WeakPolarHBondContact O-CB 3.2Å; S187-Q191 PolarHBondContact O-N 2.94Å; A188-Q191 WeakPolarHBondContact O-CB 3.21Å; A188-Q191 PolarHBondContact O-N 3.49Å; R189-Q191 VanDerWaalsContact C-N 3.29Å; R189-Q191 PolarHBondContact O-N 3.33Å; Q191-L194 PolarHBondContact O-N 2.99Å; Q191-T195 WeakPolarHBondContact O-CB 3.46Å; Q191-T195 PolarHBondContact O-N 3.47Å; Q191-T195 PolarHBondContact O-OG1 2.92Å; Q191-G329 PolarHBondContact NE2-O 3.05Å; Q191-G329 PolarHBondContact OE1-O 3.04Å; Q191-N332 PolarHBondContact OE1-ND2 2.82Å
192	I	86	Confident	85.7	Confident	73 Å²	73	51.2 Å²	51.2	37%	0.374	25%	0.249	S	C	.	.	H	α-helix	trans	-63	-48.4	177.8	-66.4	165.3	0	0	0	110.3	R48 A188 R189 I190 L194 T195 F196	R48-I192 HydrophobicContact CG-CD1 4.34Å; A188-I192 WeakPolarHBondContact O-CG1 3.45Å; A188-I192 PolarHBondContact O-N 3.04Å; A188-I192 VanDerWaalsContact O-N 3.17Å; R189-I192 PolarHBondContact O-N 3.25Å; I190-I192 VanDerWaalsContact C-N 3.32Å; I190-I192 PolarHBondContact O-N 3.23Å; I192-L194 PolarHBondContact O-N 2.89Å; I192-T195 WeakPolarHBondContact O-CB 3.45Å; I192-T195 PolarHBondContact O-N 2.88Å; I192-T195 VanDerWaalsContact O-N 3.15Å; I192-F196 PolarHBondContact O-N 3.38Å
193	F	89.8	Confident	86	Confident	126 Å²	126	50.8 Å²	50.8	55%	0.553	25%	0.248	S	C	*	.	H	α-helix	trans	-57.9	-48.2	176.5	171.3	-102.4	0	0	0	111.8	R189 I190 T195 F196 C197	R189-F193 PolarHBondContact O-N 2.97Å; R189-F193 VanDerWaalsContact O-N 3.15Å; I190-F193 PolarHBondContact O-N 3.44Å; F193-T195 VanDerWaalsContact C-N 3.26Å; F193-T195 PolarHBondContact O-N 2.71Å; F193-F196 WeakPolarHBondContact O-CB 3.37Å; F193-F196 PolarHBondContact O-N 3.06Å; F193-F196 VanDerWaalsContact O-N 3.09Å; F193-C197 PolarHBondContact O-N 3.41Å; F193-C197 PolarHBondContact O-SG 2.98Å
194	L	90.4	Very high	86.5	Confident	6 Å²	6	50.8 Å²	50.8	3%	0.031	25%	0.246	C	C	.	.	H	α-helix	trans	-64	-32.4	177.6	-66.7	169	0	0	0	112	I190 Q191 I192 F196 C197 K198 L325 F328	I190-L194 HydrophobicContact CG2-CD1 3.48Å; I190-L194 VanDerWaalsContact CG2-CD1 3.48Å; I190-L194 HydrophobicContact CG2-CG 4.06Å; I190-L194 WeakPolarHBondContact O-CB 3.41Å; I190-L194 VanDerWaalsContact O-CG 3.23Å; I190-L194 WeakPolarHBondContact O-CG 3.35Å; I190-L194 PolarHBondContact O-N 3.4Å; Q191-L194 PolarHBondContact O-N 2.99Å; I192-L194 PolarHBondContact O-N 2.89Å; L194-F196 VanDerWaalsContact C-N 3.33Å; L194-C197 WeakPolarHBondContact O-CB 3.28Å; L194-C197 PolarHBondContact O-N 2.91Å; L194-K198 WeakPolarHBondContact O-CG 3.32Å; L194-K198 PolarHBondContact O-N 2.69Å; L194-L325 HydrophobicContact CD2-CB 4.21Å; L194-L325 HydrophobicContact CD2-CD2 4.09Å; L194-F328 HydrophobicContact CD1-CD1 3.62Å; L194-F328 HydrophobicContact CD1-CE1 4.13Å; L194-F328 HydrophobicContact CD2-CD1 4.36Å
195	T	86.9	Confident	87.4	Confident	8 Å²	8	49.3 Å²	49.3	5%	0.049	24%	0.237	C	C	.	.	H	α-helix	trans	-63.8	-40.9	173.4	-54.7	0	0	0	0	111.3	S51 I54 Q191 I192 F193 K198 L199	S51-T195 PolarHBondContact O-OG1 3.24Å; S51-T195 PolarHBondContact OG-OG1 3.19Å; I54-T195 HydrophobicContact CB-CG2 4.23Å; I54-T195 HydrophobicContact CG2-CG2 3.92Å; Q191-T195 WeakPolarHBondContact O-CB 3.46Å; Q191-T195 PolarHBondContact O-N 3.47Å; Q191-T195 PolarHBondContact O-OG1 2.92Å; I192-T195 WeakPolarHBondContact O-CB 3.45Å; I192-T195 PolarHBondContact O-N 2.88Å; I192-T195 VanDerWaalsContact O-N 3.15Å; F193-T195 VanDerWaalsContact C-N 3.26Å; F193-T195 PolarHBondContact O-N 2.71Å; T195-K198 WeakPolarHBondContact O-CB 3.11Å; T195-K198 PolarHBondContact O-N 3.31Å; T195-L199 WeakPolarHBondContact O-CG 3.45Å; T195-L199 PolarHBondContact O-N 3.43Å; T195-L199 VanDerWaalsContact O-N 3.09Å
196	F	88.8	Confident	88.1	Confident	141 Å²	141	47.8 Å²	47.8	62%	0.618	22%	0.224	S	C	*	.	H	α-helix	trans	-62	-46.8	172.6	-178.3	-97.2	0	0	0	111.2	I192 F193 L194 K198 L199 T200	I192-F196 PolarHBondContact O-N 3.38Å; F193-F196 WeakPolarHBondContact O-CB 3.37Å; F193-F196 PolarHBondContact O-N 3.06Å; F193-F196 VanDerWaalsContact O-N 3.09Å; L194-F196 VanDerWaalsContact C-N 3.33Å; F196-K198 VanDerWaalsContact C-N 3.27Å; F196-K198 PolarHBondContact O-N 3.17Å; F196-L199 PolarHBondContact O-N 3.03Å; F196-T200 PolarHBondContact O-N 3.01Å; F196-T200 PolarHBondContact O-OG1 3.45Å; F196-T200 VanDerWaalsContact O-OG1 3.07Å
197	C	89.4	Confident	88.7	Confident	7 Å²	7	44 Å²	44	5%	0.047	22%	0.219	C	C	.	.	H	α-helix	trans	-55.4	-40.6	174.6	-64.5	0	0	0	0	112.7	F193 L194 T200 A201 F322 L325	F193-C197 PolarHBondContact O-N 3.41Å; F193-C197 PolarHBondContact O-SG 2.98Å; L194-C197 WeakPolarHBondContact O-CB 3.28Å; L194-C197 PolarHBondContact O-N 2.91Å; C197-T200 PolarHBondContact O-N 3.22Å; C197-A201 WeakPolarHBondContact O-CB 3.3Å; C197-A201 PolarHBondContact O-N 2.86Å; C197-F322 HydrophobicContact CB-CD1 4.32Å; C197-L325 HydrophobicContact CB-CB 4.42Å; C197-L325 HydrophobicContact CB-CD1 4.45Å
198	K	88	Confident	89.2	Confident	0 Å²	0	44.9 Å²	44.9	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-62.2	-47.4	177.1	-72.3	168.6	-174.3	-121.8	0	112.7	G55 I58 L194 T195 F196 T200 A201 I202 S326 S330	G55-K198 PolarHBondContact O-NZ 3.06Å; I58-K198 HydrophobicContact CG2-CB 4.14Å; I58-K198 WeakPolarHBondContact O-CD 3.42Å; I58-K198 PolarHBondContact O-NZ 3.33Å; L194-K198 WeakPolarHBondContact O-CG 3.32Å; L194-K198 PolarHBondContact O-N 2.69Å; T195-K198 WeakPolarHBondContact O-CB 3.11Å; T195-K198 PolarHBondContact O-N 3.31Å; F196-K198 VanDerWaalsContact C-N 3.27Å; F196-K198 PolarHBondContact O-N 3.17Å; K198-T200 VanDerWaalsContact C-N 3.32Å; K198-A201 WeakPolarHBondContact O-CB 3.37Å; K198-A201 PolarHBondContact O-N 3.4Å; K198-I202 PolarHBondContact O-N 3.42Å; K198-I202 VanDerWaalsContact O-N 3.13Å; K198-S326 WeakPolarHBondContact CE-O 3.37Å; K198-S326 WeakPolarHBondContact CG-OG 3.5Å; K198-S326 PolarHBondContact NZ-O 3.31Å; K198-S330 VanDerWaalsContact NZ-N 3.16Å; K198-S330 PolarHBondContact NZ-OG 3.04Å
199	L	89.2	Confident	89.8	Confident	57 Å²	57	43.4 Å²	43.4	30%	0.298	21%	0.212	S	C	.	.	H	α-helix	trans	-64.5	-41.5	178.8	-68.6	176.7	0	0	0	110.4	I54 I58 T195 F196 A201 I202 L203 I276	I54-L199 HydrophobicContact CG2-CD2 3.96Å; I54-L199 HydrophobicContact CG2-CG 4.41Å; I58-L199 HydrophobicContact CD1-CD2 4.08Å; T195-L199 WeakPolarHBondContact O-CG 3.45Å; T195-L199 PolarHBondContact O-N 3.43Å; T195-L199 VanDerWaalsContact O-N 3.09Å; F196-L199 PolarHBondContact O-N 3.03Å; L199-A201 VanDerWaalsContact C-N 3.35Å; L199-A201 PolarHBondContact O-N 3.42Å; L199-I202 PolarHBondContact O-N 3.26Å; L199-L203 VanDerWaalsContact O-CG 3.3Å; L199-L203 WeakPolarHBondContact O-CG 3.25Å; L199-L203 PolarHBondContact O-N 3.03Å; L199-I276 HydrophobicContact CD2-CG2 4.43Å
200	T	89.6	Confident	90.2	Very high	36 Å²	36	39 Å²	39	22%	0.221	20%	0.203	C	C	.	.	H	α-helix	trans	-60.1	-42.9	172.8	-57.8	0	0	0	0	111.9	F196 C197 K198 I202 L203 I204 F322	F196-T200 PolarHBondContact O-N 3.01Å; F196-T200 PolarHBondContact O-OG1 3.45Å; F196-T200 VanDerWaalsContact O-OG1 3.07Å; C197-T200 PolarHBondContact O-N 3.22Å; K198-T200 VanDerWaalsContact C-N 3.32Å; T200-I202 VanDerWaalsContact C-N 3.31Å; T200-I202 PolarHBondContact O-N 3.12Å; T200-L203 PolarHBondContact O-N 3.12Å; T200-L203 VanDerWaalsContact O-N 3.16Å; T200-I204 HydrophobicContact CG2-CD1 3.92Å; T200-I204 HydrophobicContact CG2-CG1 4.39Å; T200-I204 VanDerWaalsContact O-CG1 3.3Å; T200-I204 WeakPolarHBondContact O-CG1 3.5Å; T200-I204 PolarHBondContact O-N 3.21Å; T200-F322 HydrophobicContact CG2-CZ 4.42Å
201	A	88.8	Confident	90.5	Very high	3 Å²	3	41.8 Å²	41.8	3%	0.025	22%	0.216	C	C	.	.	H	α-helix	trans	-56.3	-45.6	176.8	0	0	0	0	0	112	C197 K198 L199 I204 I205 F322	C197-A201 WeakPolarHBondContact O-CB 3.3Å; C197-A201 PolarHBondContact O-N 2.86Å; K198-A201 WeakPolarHBondContact O-CB 3.37Å; K198-A201 PolarHBondContact O-N 3.4Å; L199-A201 VanDerWaalsContact C-N 3.35Å; L199-A201 PolarHBondContact O-N 3.42Å; A201-I204 PolarHBondContact O-N 2.85Å; A201-I205 PolarHBondContact O-N 3.44Å; A201-F322 HydrophobicContact CB-CB 3.7Å
202	I	90.8	Very high	90.9	Very high	9 Å²	9	42.8 Å²	42.8	5%	0.046	22%	0.22	C	C	.	.	H	α-helix	trans	-66.8	-42.4	177.4	-75.6	174.2	0	0	0	111	I58 K198 L199 T200 I204 I205 I206	I58-I202 HydrophobicContact CB-CD1 4.49Å; I58-I202 HydrophobicContact CD1-CD1 3.65Å; I58-I202 HydrophobicContact CG1-CD1 4.3Å; I58-I202 HydrophobicContact CG2-CD1 3.47Å; I58-I202 VanDerWaalsContact CG2-CD1 3.47Å; I58-I202 HydrophobicContact CG2-CG1 4.44Å; K198-I202 PolarHBondContact O-N 3.42Å; K198-I202 VanDerWaalsContact O-N 3.13Å; L199-I202 PolarHBondContact O-N 3.26Å; T200-I202 VanDerWaalsContact C-N 3.31Å; T200-I202 PolarHBondContact O-N 3.12Å; I202-I204 VanDerWaalsContact C-N 3.31Å; I202-I204 PolarHBondContact O-N 3.2Å; I202-I205 PolarHBondContact O-N 2.77Å; I202-I206 HydrophobicContact CG2-CD1 3.33Å; I202-I206 HydrophobicContact CG2-CG1 3.96Å; I202-I206 WeakPolarHBondContact O-CG1 3.34Å; I202-I206 PolarHBondContact O-N 3.35Å
203	L	91.9	Very high	91.2	Very high	96 Å²	96	42.7 Å²	42.7	50%	0.503	22%	0.22	S	C	.	.	H	α-helix	trans	-64	-35.6	178.5	-71.2	173.2	0	0	0	112.5	L199 T200 I205 I206 V207	L199-L203 VanDerWaalsContact O-CG 3.3Å; L199-L203 WeakPolarHBondContact O-CG 3.25Å; L199-L203 PolarHBondContact O-N 3.03Å; T200-L203 PolarHBondContact O-N 3.12Å; T200-L203 VanDerWaalsContact O-N 3.16Å; L203-I205 PolarHBondContact O-N 3.46Å; L203-I206 PolarHBondContact O-N 3.34Å; L203-V207 WeakPolarHBondContact O-CB 3.47Å; L203-V207 WeakPolarHBondContact O-CG2 3.31Å; L203-V207 PolarHBondContact O-N 2.93Å
204	I	91.2	Very high	91.3	Very high	26 Å²	26	43.4 Å²	43.4	13%	0.133	23%	0.228	C	C	.	.	H	α-helix	trans	-62.1	-24.2	173.7	-70.2	165.2	0	0	0	111.7	T200 A201 I202 P208 L312 F315 V319 F322	T200-I204 HydrophobicContact CG2-CD1 3.92Å; T200-I204 HydrophobicContact CG2-CG1 4.39Å; T200-I204 VanDerWaalsContact O-CG1 3.3Å; T200-I204 WeakPolarHBondContact O-CG1 3.5Å; T200-I204 PolarHBondContact O-N 3.21Å; A201-I204 PolarHBondContact O-N 2.85Å; I202-I204 VanDerWaalsContact C-N 3.31Å; I202-I204 PolarHBondContact O-N 3.2Å; I204-P208 WeakPolarHBondContact O-CD 3.44Å; I204-P208 WeakPolarHBondContact O-CG 3.42Å; I204-L312 HydrophobicContact CG2-CD1 3.74Å; I204-F315 HydrophobicContact CD1-CE1 4.01Å; I204-F315 HydrophobicContact CD1-CZ 4.08Å; I204-F315 HydrophobicContact CG1-CE1 4.24Å; I204-F315 HydrophobicContact CG2-CE1 3.92Å; I204-V319 HydrophobicContact CG2-CG2 3.8Å; I204-F322 HydrophobicContact CD1-CD2 3.65Å; I204-F322 HydrophobicContact CD1-CE2 3.6Å; I204-F322 HydrophobicContact CD1-CZ 4.48Å
205	I	92.1	Very high	91.5	Very high	1 Å²	1	50 Å²	50	1%	0.005	26%	0.256	C	S	.	.	H	α-helix	trans	-89.7	-47.8	174.4	-63.4	162.8	0	0	0	110.7	F63 A201 I202 L203 G209 T284 A287 Y288 A304 F307	F63-I205 HydrophobicContact CE1-CD1 3.99Å; A201-I205 PolarHBondContact O-N 3.44Å; I202-I205 PolarHBondContact O-N 2.77Å; L203-I205 PolarHBondContact O-N 3.46Å; I205-G209 PolarHBondContact O-N 3.34Å; I205-T284 HydrophobicContact CG2-CG2 4.01Å; I205-A287 HydrophobicContact CG2-CB 3.88Å; I205-A287 WeakPolarHBondContact O-CB 3.22Å; I205-Y288 HydrophobicContact CD1-CE1 4.23Å; I205-Y288 HydrophobicContact CG2-CD1 4.06Å; I205-Y288 HydrophobicContact CG2-CE1 3.65Å; I205-A304 HydrophobicContact CD1-CB 4.14Å; I205-F307 HydrophobicContact CB-CE1 4.27Å; I205-F307 HydrophobicContact CG1-CD1 4.32Å; I205-F307 HydrophobicContact CG1-CE1 4.4Å; I205-F307 HydrophobicContact CG2-CD1 4.16Å; I205-F307 HydrophobicContact CG2-CE1 3.96Å; I205-F307 HydrophobicContact CG2-CZ 4.18Å; I205-F307 WeakPolarHBondContact O-CZ 3.26Å
206	I	94.4	Very high	91.7	Very high	17 Å²	17	51.7 Å²	51.7	9%	0.087	28%	0.276	C	S	.	.	H	α-helix	trans	-64.1	-50.6	-175.3	-67.9	176.6	0	0	0	111.6	I202 L203 G209 V210 L283	I202-I206 HydrophobicContact CG2-CD1 3.33Å; I202-I206 HydrophobicContact CG2-CG1 3.96Å; I202-I206 WeakPolarHBondContact O-CG1 3.34Å; I202-I206 PolarHBondContact O-N 3.35Å; L203-I206 PolarHBondContact O-N 3.34Å; I206-G209 PolarHBondContact O-N 2.86Å; I206-V210 HydrophobicContact CG2-CG2 4.07Å; I206-V210 WeakPolarHBondContact O-CG2 3.28Å; I206-V210 PolarHBondContact O-N 3.33Å; I206-L283 HydrophobicContact CD1-CB 3.7Å; I206-L283 HydrophobicContact CD1-CD1 4.34Å; I206-L283 HydrophobicContact CG1-CB 3.9Å; I206-L283 HydrophobicContact CG2-CB 4.1Å; I206-L283 HydrophobicContact CG2-CD1 4.2Å
207	V	94.8	Very high	91.8	Very high	79 Å²	79	49.2 Å²	49.2	48%	0.479	27%	0.266	S	S	.	.	H	α-helix	trans	-61.1	-50	-172.6	172.1	0	0	0	0	111.2	L203 G209 V210 M211	L203-V207 WeakPolarHBondContact O-CB 3.47Å; L203-V207 WeakPolarHBondContact O-CG2 3.31Å; L203-V207 PolarHBondContact O-N 2.93Å; V207-G209 VanDerWaalsContact C-N 3.34Å; V207-G209 PolarHBondContact O-N 2.94Å; V207-V210 PolarHBondContact O-N 2.89Å; V207-M211 HydrophobicContact CG1-SD 4.35Å; V207-M211 WeakPolarHBondContact O-CG 3.31Å; V207-M211 PolarHBondContact O-N 2.82Å
208	P	93.1	Very high	91.9	Very high	20 Å²	20	51.3 Å²	51.3	13%	0.13	28%	0.279	C	S	.	.	H	α-helix	trans	-64.7	-35	176.2	-25.2	39.4	0	0	0	113.4	I204 M211 Q212 F307 L311 L312	I204-P208 WeakPolarHBondContact O-CD 3.44Å; I204-P208 WeakPolarHBondContact O-CG 3.42Å; P208-M211 WeakPolarHBondContact O-CB 3.06Å; P208-M211 PolarHBondContact O-N 3.37Å; P208-Q212 WeakPolarHBondContact O-CG 3.37Å; P208-Q212 PolarHBondContact O-N 3.5Å; P208-F307 HydrophobicContact CB-CZ 4.43Å; P208-L311 HydrophobicContact CB-CD2 3.25Å; P208-L311 HydrophobicContact CB-CG 4.26Å; P208-L312 HydrophobicContact CB-CD2 4.29Å; P208-L312 HydrophobicContact CG-CD2 3.97Å
209	G	92.8	Very high	91.8	Very high	2 Å²	2	57.6 Å²	57.6	2%	0.021	31%	0.308	C	S	.	.	H	α-helix	trans	-64.2	-41.7	174.2	0	0	0	0	0	113.1	I205 I206 V207 M211 Q212 L213 T290	I205-G209 PolarHBondContact O-N 3.34Å; I206-G209 PolarHBondContact O-N 2.86Å; V207-G209 VanDerWaalsContact C-N 3.34Å; V207-G209 PolarHBondContact O-N 2.94Å; G209-M211 VanDerWaalsContact C-N 3.32Å; G209-M211 PolarHBondContact O-N 3.29Å; G209-Q212 WeakPolarHBondContact O-CB 3.32Å; G209-Q212 PolarHBondContact O-N 3.07Å; G209-L213 PolarHBondContact O-N 3.47Å; G209-T290 WeakPolarHBondContact CA-OG1 3.5Å; G209-T290 PolarHBondContact O-OG1 3.4Å
210	V	93.1	Very high	91.7	Very high	61 Å²	61	57.1 Å²	57.1	37%	0.37	31%	0.306	S	S	.	.	H	α-helix	trans	-63.9	-38.9	173.3	172.4	0	0	0	0	110.8	I206 V207 Q212 L213 I214	I206-V210 HydrophobicContact CG2-CG2 4.07Å; I206-V210 WeakPolarHBondContact O-CG2 3.28Å; I206-V210 PolarHBondContact O-N 3.33Å; V207-V210 PolarHBondContact O-N 2.89Å; V210-Q212 VanDerWaalsContact C-N 3.32Å; V210-Q212 PolarHBondContact O-N 3.36Å; V210-L213 WeakPolarHBondContact O-CB 3.35Å; V210-L213 PolarHBondContact O-N 2.98Å; V210-I214 HydrophobicContact CG1-CD1 4.05Å; V210-I214 WeakPolarHBondContact O-CG1 3.23Å; V210-I214 PolarHBondContact O-N 3.3Å
211	M	94.1	Very high	91.6	Very high	101 Å²	101	57.9 Å²	57.9	50%	0.498	31%	0.306	S	S	.	.	H	α-helix	trans	-62	-39	173.6	-68.4	173.7	67.9	0	0	112.2	V207 P208 G209 L213 I214 K215	V207-M211 HydrophobicContact CG1-SD 4.35Å; V207-M211 WeakPolarHBondContact O-CG 3.31Å; V207-M211 PolarHBondContact O-N 2.82Å; P208-M211 WeakPolarHBondContact O-CB 3.06Å; P208-M211 PolarHBondContact O-N 3.37Å; G209-M211 VanDerWaalsContact C-N 3.32Å; G209-M211 PolarHBondContact O-N 3.29Å; M211-L213 VanDerWaalsContact C-N 3.34Å; M211-I214 PolarHBondContact O-N 2.86Å; M211-K215 WeakPolarHBondContact O-CG 3.34Å; M211-K215 PolarHBondContact O-N 3.49Å
212	Q	93.6	Very high	91.5	Very high	29 Å²	29	64.4 Å²	64.4	14%	0.136	33%	0.334	C	S	.	.	H	α-helix	trans	-65.3	-38.6	174.2	-70.8	-74.5	71	0	0	111.9	P208 G209 V210 K215 G216 Q217 L311	P208-Q212 WeakPolarHBondContact O-CG 3.37Å; P208-Q212 PolarHBondContact O-N 3.5Å; G209-Q212 WeakPolarHBondContact O-CB 3.32Å; G209-Q212 PolarHBondContact O-N 3.07Å; V210-Q212 VanDerWaalsContact C-N 3.32Å; V210-Q212 PolarHBondContact O-N 3.36Å; Q212-K215 PolarHBondContact O-N 3.41Å; Q212-G216 PolarHBondContact O-N 3.43Å; Q212-Q217 HydrophobicContact CB-CB 4.26Å; Q212-Q217 HydrophobicContact CB-CG 4.42Å; Q212-Q217 WeakPolarHBondContact O-CB 3.04Å; Q212-Q217 PolarHBondContact O-N 3.2Å; Q212-L311 HydrophobicContact CG-CD1 3.87Å; Q212-L311 HydrophobicContact CG-CD2 4.05Å
213	L	92.4	Very high	91.3	Very high	71 Å²	71	69.6 Å²	69.6	37%	0.372	36%	0.362	S	S	.	.	H	α-helix	trans	-61.5	-45.1	173.9	-168.3	69.6	0	0	0	111.7	G209 V210 M211 K215 G216 T218 F221 T290	G209-L213 PolarHBondContact O-N 3.47Å; V210-L213 WeakPolarHBondContact O-CB 3.35Å; V210-L213 PolarHBondContact O-N 2.98Å; M211-L213 VanDerWaalsContact C-N 3.34Å; L213-K215 VanDerWaalsContact C-N 3.28Å; L213-K215 PolarHBondContact O-N 2.84Å; L213-G216 WeakPolarHBondContact O-CA 3.35Å; L213-G216 PolarHBondContact O-N 2.92Å; L213-T218 HydrophobicContact CD1-CG2 3.63Å; L213-F221 HydrophobicContact CD1-CE2 4.5Å; L213-T290 HydrophobicContact CB-CG2 4.09Å; L213-T290 HydrophobicContact CD1-CG2 4.01Å
214	I	93.1	Very high	91.1	Very high	141 Å²	141	65.7 Å²	65.7	72%	0.723	34%	0.344	S	S	*	.	H	α-helix	trans	-62.5	-35.9	176.4	-67.2	166	0	0	0	111.3	V210 M211 G216	V210-I214 HydrophobicContact CG1-CD1 4.05Å; V210-I214 WeakPolarHBondContact O-CG1 3.23Å; V210-I214 PolarHBondContact O-N 3.3Å; M211-I214 PolarHBondContact O-N 2.86Å; I214-G216 PolarHBondContact O-N 3.4Å
215	K	93.4	Very high	90.9	Very high	144 Å²	144	71.3 Å²	71.3	63%	0.626	37%	0.367	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.6	-2.8	173.4	-71.9	173.5	179.3	-179.8	0	113.8	M211 Q212 L213	M211-K215 WeakPolarHBondContact O-CG 3.34Å; M211-K215 PolarHBondContact O-N 3.49Å; Q212-K215 PolarHBondContact O-N 3.41Å; L213-K215 VanDerWaalsContact C-N 3.28Å; L213-K215 PolarHBondContact O-N 2.84Å
216	G	91.3	Very high	90.4	Very high	44 Å²	44	75 Å²	75	45%	0.454	39%	0.394	S	S	.	.	T	Hydrogen-bonded Turn	trans	86.9	13.8	177.6	0	0	0	0	0	114.8	Q212 L213 I214 T218	Q212-G216 PolarHBondContact O-N 3.43Å; L213-G216 WeakPolarHBondContact O-CA 3.35Å; L213-G216 PolarHBondContact O-N 2.92Å; I214-G216 PolarHBondContact O-N 3.4Å; G216-T218 PolarHBondContact O-N 2.95Å; G216-T218 PolarHBondContact O-OG1 3.47Å
217	Q	91.3	Very high	89.4	Confident	90 Å²	90	76.5 Å²	76.5	42%	0.421	41%	0.413	S	S	.	.			trans	-73	72.4	176	-61.5	-61.9	-19.4	0	0	111.2	Q212	Q212-Q217 HydrophobicContact CB-CB 4.26Å; Q212-Q217 HydrophobicContact CB-CG 4.42Å; Q212-Q217 WeakPolarHBondContact O-CB 3.04Å; Q212-Q217 PolarHBondContact O-N 3.2Å
218	T	90.1	Very high	88	Confident	50 Å²	50	83.3 Å²	83.3	31%	0.307	43%	0.43	S	S	.	.			trans	-115	10.3	-173.1	52.3	0	0	0	0	113.3	L213 G216 N220 F221 K222	L213-T218 HydrophobicContact CD1-CG2 3.63Å; G216-T218 PolarHBondContact O-N 2.95Å; G216-T218 PolarHBondContact O-OG1 3.47Å; T218-N220 VanDerWaalsContact C-N 3.3Å; T218-N220 PolarHBondContact O-N 2.99Å; T218-F221 WeakPolarHBondContact O-CA 3.29Å; T218-F221 WeakPolarHBondContact O-CB 3.46Å; T218-F221 PolarHBondContact O-N 3.06Å; T218-K222 PolarHBondContact O-N 3.2Å
219	Q	87.8	Confident	86.5	Confident	132 Å²	132	89.7 Å²	89.7	62%	0.617	46%	0.463	S	S	*	.	H	α-helix	trans	-51.8	-47.5	-174.2	-63.9	-84	21.1	0	0	112	F221 K222	Q219-F221 PolarHBondContact O-N 2.84Å; Q219-F221 VanDerWaalsContact O-N 3.14Å; Q219-K222 PolarHBondContact O-N 2.9Å
220	N	85.9	Confident	84.9	Confident	47 Å²	47	93.6 Å²	93.6	25%	0.251	49%	0.49	S	S	.	.	H	α-helix	trans	-68.1	-10.9	-180	-65.2	-36.8	0	0	0	114.2	T218 F289 I292	T218-N220 VanDerWaalsContact C-N 3.3Å; T218-N220 PolarHBondContact O-N 2.99Å; N220-F289 WeakPolarHBondContact CB-O 3.28Å; N220-F289 PolarHBondContact ND2-O 3.32Å; N220-I292 PolarHBondContact ND2-O 3.4Å; N220-I292 VanDerWaalsContact ND2-O 3.12Å
221	F	88.4	Confident	83.6	Confident	52 Å²	52	92.6 Å²	92.6	23%	0.228	49%	0.486	C	S	.	.	H	α-helix	trans	-101.2	-12.9	179.4	-58	-79.5	0	0	0	113.8	V76 L80 L213 T218 Q219 A224 V286 F289 T290	V76-F221 HydrophobicContact CG1-CD1 4.43Å; V76-F221 HydrophobicContact CG1-CE1 4.34Å; L80-F221 HydrophobicContact CD1-CE1 3.99Å; L213-F221 HydrophobicContact CD1-CE2 4.5Å; T218-F221 WeakPolarHBondContact O-CA 3.29Å; T218-F221 WeakPolarHBondContact O-CB 3.46Å; T218-F221 PolarHBondContact O-N 3.06Å; Q219-F221 PolarHBondContact O-N 2.84Å; Q219-F221 VanDerWaalsContact O-N 3.14Å; F221-A224 PolarHBondContact O-N 3.4Å; F221-V286 HydrophobicContact CZ-CG1 3.98Å; F221-F289 HydrophobicContact CE1-CB 4.12Å; F221-F289 HydrophobicContact CE2-CB 4.28Å; F221-F289 HydrophobicContact CZ-CB 3.66Å; F221-T290 HydrophobicContact CE2-CG2 3.72Å; F221-T290 HydrophobicContact CZ-CG2 4.18Å
222	K	86.8	Confident	82.6	Confident	141 Å²	141	94.8 Å²	94.8	61%	0.613	50%	0.498	S	S	*	.	H	α-helix	trans	-62.9	-45.9	-177.7	-74.5	-178.4	177.9	174.3	0	112.1	T218 Q219	T218-K222 PolarHBondContact O-N 3.2Å; Q219-K222 PolarHBondContact O-N 2.9Å
223	D	85.6	Confident	81.7	Confident	118 Å²	118	97.8 Å²	97.8	63%	0.631	52%	0.518	S	S	*	.	T	Hydrogen-bonded Turn	trans	-115.6	47	174	-58.7	-55.7	0	0	0	110.3	F225 S226	D223-F225 PolarHBondContact O-N 3.3Å; D223-S226 WeakPolarHBondContact CB-OG 3.49Å; D223-S226 WeakPolarHBondContact O-CB 3.32Å; D223-S226 PolarHBondContact O-N 2.89Å; D223-S226 PolarHBondContact O-OG 3.43Å
224	A	87.2	Confident	81.2	Confident	14 Å²	14	101 Å²	101	12%	0.116	53%	0.526	C	S	.	.	T	Hydrogen-bonded Turn	trans	-54.2	-33.9	-170.3	0	0	0	0	0	113.6	S75 V76 G77 F221	S75-A224 PolarHBondContact OG-O 3.42Å; V76-A224 PolarHBondContact N-O 3.45Å; G77-A224 PolarHBondContact N-O 2.96Å; F221-A224 PolarHBondContact O-N 3.4Å
225	F	88.8	Confident	80.8	Confident	143 Å²	143	96.4 Å²	96.4	63%	0.627	50%	0.502	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.2	-8.9	180	-66.2	-80.8	0	0	0	113.8	S75 G77 D223	S75-F225 WeakPolarHBondContact OG-CA 3.37Å; G77-F225 VanDerWaalsContact C-CE1 3.48Å; D223-F225 PolarHBondContact O-N 3.3Å
226	S	80.8	Confident	80.4	Confident	80 Å²	80	90.6 Å²	90.6	56%	0.559	48%	0.479	S	S	*	.			trans	-74.4	134.2	170	79.1	0	0	0	0	109.2	D223	D223-S226 WeakPolarHBondContact CB-OG 3.49Å; D223-S226 WeakPolarHBondContact O-CB 3.32Å; D223-S226 PolarHBondContact O-N 2.89Å; D223-S226 PolarHBondContact O-OG 3.43Å
227	G	72.4	Confident	80.1	Confident	48 Å²	48	90.7 Å²	90.7	50%	0.495	47%	0.469	S	S	.	.			trans	-176.5	168.3	-172.5	0	0	0	0	0	111.4	G74	G74-G227 WeakPolarHBondContact O-CA 3.23Å
228	R	66.6	Low	80	Confident	222 Å²	222	86.4 Å²	86.4	84%	0.838	45%	0.449	S	S	*	.	S	Bend	trans	-57.2	145.7	170.4	-82.2	-177.9	-179.2	159	2.4	109.3	S230	R228-S230 PolarHBondContact O-N 3.34Å
229	D	61.6	Low	80.1	Confident	154 Å²	154	85.7 Å²	85.7	82%	0.824	44%	0.442	S	S	*	.			trans	-22.7	102.4	179.6	-84.9	-26.1	0	0	0	112.1	S231	D229-S231 PolarHBondContact O-N 3.21Å
230	S	59.7	Low	80	Confident	83 Å²	83	79.6 Å²	79.6	58%	0.58	41%	0.413	S	S	*	.			trans	-73.2	61.5	173.6	30.6	0	0	0	0	108.3	R228 I232	R228-S230 PolarHBondContact O-N 3.34Å; S230-I232 PolarHBondContact O-N 3.1Å; S230-I232 VanDerWaalsContact O-N 3.12Å
231	S	64.1	Low	80.1	Confident	41 Å²	41	79.1 Å²	79.1	29%	0.287	41%	0.408	S	S	.	.			trans	-57.5	119.7	176.5	60.4	0	0	0	0	107.9	D229 T233 R234	D229-S231 PolarHBondContact O-N 3.21Å; S231-T233 WeakPolarHBondContact CB-OG1 3.47Å; S231-T233 PolarHBondContact O-N 2.94Å; S231-T233 PolarHBondContact OG-OG1 3.05Å; S231-R234 PolarHBondContact O-N 3.27Å
232	I	73.2	Confident	80.3	Confident	146 Å²	146	76.7 Å²	76.7	75%	0.749	40%	0.397	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.3	-23.2	177.5	-63.5	170.9	0	0	0	110.5	S230 R234 L235 P236	S230-I232 PolarHBondContact O-N 3.1Å; S230-I232 VanDerWaalsContact O-N 3.12Å; I232-R234 PolarHBondContact O-N 3.44Å; I232-L235 WeakPolarHBondContact O-CB 3.48Å; I232-L235 PolarHBondContact O-N 2.88Å; I232-P236 VanDerWaalsContact O-CD 3.29Å; I232-P236 WeakPolarHBondContact O-CD 3.31Å
233	T	75.9	Confident	80.5	Confident	93 Å²	93	70 Å²	70	57%	0.571	37%	0.368	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65	-28	177.2	56.6	0	0	0	0	114.6	S231 P236	S231-T233 WeakPolarHBondContact CB-OG1 3.47Å; S231-T233 PolarHBondContact O-N 2.94Å; S231-T233 PolarHBondContact OG-OG1 3.05Å; T233-P236 WeakPolarHBondContact O-CD 3.45Å
234	R	81.8	Confident	80.6	Confident	139 Å²	139	65.5 Å²	65.5	53%	0.525	34%	0.342	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94	-18.8	178.6	-65.9	-175.7	-174.8	179.1	2.6	113.7	N72 S231 I232 P236 L237 A238	N72-R234 WeakPolarHBondContact O-CB 3.49Å; S231-R234 PolarHBondContact O-N 3.27Å; I232-R234 PolarHBondContact O-N 3.44Å; R234-P236 VanDerWaalsContact C-N 3.31Å; R234-L237 WeakPolarHBondContact O-CB 3.29Å; R234-L237 PolarHBondContact O-N 3.36Å; R234-A238 PolarHBondContact O-N 3.36Å
235	L	84.6	Confident	80.9	Confident	43 Å²	43	64.9 Å²	64.9	23%	0.225	34%	0.338	C	S	.	.	H	α-helix	trans	-52.4	-40.3	179.1	-170.4	68.9	0	0	0	114.3	M78 I82 I232 L237 A238 F239	M78-L235 HydrophobicContact CE-CD1 3.4Å; M78-L235 HydrophobicContact CE-CD2 4.01Å; M78-L235 HydrophobicContact CE-CG 4.37Å; M78-L235 HydrophobicContact CG-CD1 4.45Å; I82-L235 HydrophobicContact CD1-CD1 3.35Å; I82-L235 HydrophobicContact CD1-CG 4.44Å; I82-L235 HydrophobicContact CG1-CD1 4.18Å; I232-L235 WeakPolarHBondContact O-CB 3.48Å; I232-L235 PolarHBondContact O-N 2.88Å; L235-L237 VanDerWaalsContact C-N 3.32Å; L235-L237 PolarHBondContact O-N 2.92Å; L235-A238 WeakPolarHBondContact O-CB 3.27Å; L235-A238 PolarHBondContact O-N 3.08Å; L235-A238 VanDerWaalsContact O-N 3.09Å; L235-F239 HydrophobicContact CD1-CE2 4.4Å; L235-F239 HydrophobicContact CD2-CE2 4.14Å; L235-F239 HydrophobicContact CG-CD2 4.17Å; L235-F239 HydrophobicContact CG-CE2 3.92Å; L235-F239 WeakPolarHBondContact O-CD2 3.41Å; L235-F239 PolarHBondContact O-N 3.37Å; L235-F239 VanDerWaalsContact O-N 3.13Å
236	P	85.5	Confident	81	Confident	23 Å²	23	58.1 Å²	58.1	15%	0.149	31%	0.308	C	S	.	.	H	α-helix	trans	-56.8	-43.6	176	-25.9	35.7	0	0	0	112.6	I232 T233 R234 A238 F239 Y240 F437 L441	I232-P236 VanDerWaalsContact O-CD 3.29Å; I232-P236 WeakPolarHBondContact O-CD 3.31Å; T233-P236 WeakPolarHBondContact O-CD 3.45Å; R234-P236 VanDerWaalsContact C-N 3.31Å; P236-A238 PolarHBondContact O-N 3.49Å; P236-F239 WeakPolarHBondContact O-CA 3.46Å; P236-F239 WeakPolarHBondContact O-CB 3.43Å; P236-F239 PolarHBondContact O-N 2.79Å; P236-F239 VanDerWaalsContact O-N 3.08Å; P236-Y240 PolarHBondContact O-N 2.98Å; P236-F437 HydrophobicContact CB-CE1 4.25Å; P236-F437 HydrophobicContact CB-CZ 3.81Å; P236-F437 HydrophobicContact CG-CZ 3.86Å; P236-L441 HydrophobicContact CB-CB 4.44Å; P236-L441 HydrophobicContact CB-CD1 3.27Å; P236-L441 HydrophobicContact CB-CD2 3.49Å; P236-L441 VanDerWaalsContact CB-CD2 3.49Å; P236-L441 HydrophobicContact CB-CG 3.86Å; P236-L441 HydrophobicContact CG-CD1 4.31Å; P236-L441 WeakPolarHBondContact O-CD2 3.25Å
237	L	84.3	Confident	81.3	Confident	45 Å²	45	55.1 Å²	55.1	24%	0.236	29%	0.288	C	S	.	.	H	α-helix	trans	-62.3	-31.6	177.7	-78.2	168.7	0	0	0	112.2	N72 R234 L235 Y240 Y241 S445	N72-L237 HydrophobicContact CB-CB 4.2Å; N72-L237 WeakPolarHBondContact OD1-CB 3.44Å; R234-L237 WeakPolarHBondContact O-CB 3.29Å; R234-L237 PolarHBondContact O-N 3.36Å; L235-L237 VanDerWaalsContact C-N 3.32Å; L235-L237 PolarHBondContact O-N 2.92Å; L237-Y240 VanDerWaalsContact O-CB 3.29Å; L237-Y240 WeakPolarHBondContact O-CB 3.44Å; L237-Y240 PolarHBondContact O-N 2.61Å; L237-Y241 VanDerWaalsContact O-CD2 3.24Å; L237-Y241 WeakPolarHBondContact O-CD2 3.32Å; L237-Y241 PolarHBondContact O-N 3.35Å; L237-Y241 VanDerWaalsContact O-N 3.16Å; L237-S445 WeakPolarHBondContact CD2-OG 3.35Å
238	A	89.8	Confident	82	Confident	0 Å²	0	52.9 Å²	52.9	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-68.7	-41.1	173.2	0	0	0	0	0	112.1	V69 N72 T73 I82 R234 L235 P236 Y240 Y241 G242	V69-A238 HydrophobicContact CG1-CB 4.46Å; N72-A238 HydrophobicContact CB-CB 3.79Å; T73-A238 HydrophobicContact CG2-CB 3.71Å; I82-A238 HydrophobicContact CD1-CB 3.35Å; R234-A238 PolarHBondContact O-N 3.36Å; L235-A238 WeakPolarHBondContact O-CB 3.27Å; L235-A238 PolarHBondContact O-N 3.08Å; L235-A238 VanDerWaalsContact O-N 3.09Å; P236-A238 PolarHBondContact O-N 3.49Å; A238-Y240 PolarHBondContact O-N 3.19Å; A238-Y241 PolarHBondContact O-N 2.89Å; A238-G242 PolarHBondContact O-N 3.07Å
239	F	90.6	Very high	83.2	Confident	35 Å²	35	42.3 Å²	42.3	15%	0.154	23%	0.225	C	C	.	.	H	α-helix	trans	-58.9	-36.2	169.9	-83.5	-75	0	0	0	111.8	I82 V85 L89 L235 P236 G242 M243 M438	I82-F239 HydrophobicContact CG1-CZ 4.49Å; I82-F239 HydrophobicContact CG2-CD1 4.41Å; V85-F239 HydrophobicContact CB-CE1 4.07Å; V85-F239 HydrophobicContact CB-CZ 4.45Å; V85-F239 HydrophobicContact CG1-CE1 3.61Å; V85-F239 HydrophobicContact CG1-CZ 4Å; L89-F239 HydrophobicContact CD1-CE1 4.24Å; L235-F239 HydrophobicContact CD1-CE2 4.4Å; L235-F239 HydrophobicContact CD2-CE2 4.14Å; L235-F239 HydrophobicContact CG-CD2 4.17Å; L235-F239 HydrophobicContact CG-CE2 3.92Å; L235-F239 WeakPolarHBondContact O-CD2 3.41Å; L235-F239 PolarHBondContact O-N 3.37Å; L235-F239 VanDerWaalsContact O-N 3.13Å; P236-F239 WeakPolarHBondContact O-CA 3.46Å; P236-F239 WeakPolarHBondContact O-CB 3.43Å; P236-F239 PolarHBondContact O-N 2.79Å; P236-F239 VanDerWaalsContact O-N 3.08Å; F239-G242 PolarHBondContact O-N 3.43Å; F239-M243 VanDerWaalsContact O-CB 3.27Å; F239-M243 WeakPolarHBondContact O-CB 3.38Å; F239-M243 WeakPolarHBondContact O-CG 3.28Å; F239-M243 PolarHBondContact O-N 3.18Å; F239-M438 HydrophobicContact CB-SD 4.42Å
240	Y	86.3	Confident	84.5	Confident	5 Å²	5	35.4 Å²	35.4	2%	0.02	19%	0.188	C	C	.	.	H	α-helix	trans	-60	-52.6	176.6	176.7	-86.6	0	0	0	113.4	P236 L237 A238 G242 Y244 L389 N390 S393 M438	P236-Y240 PolarHBondContact O-N 2.98Å; L237-Y240 VanDerWaalsContact O-CB 3.29Å; L237-Y240 WeakPolarHBondContact O-CB 3.44Å; L237-Y240 PolarHBondContact O-N 2.61Å; A238-Y240 PolarHBondContact O-N 3.19Å; Y240-G242 VanDerWaalsContact C-N 3.33Å; Y240-G242 PolarHBondContact O-N 3.49Å; Y240-Y244 PolarHBondContact O-N 3.14Å; Y240-Y244 VanDerWaalsContact O-N 3.09Å; Y240-L389 PolarHBondContact OH-O 2.86Å; Y240-N390 VanDerWaalsContact CZ-OD1 3.26Å; Y240-N390 WeakPolarHBondContact OH-CA 3.11Å; Y240-N390 PolarHBondContact OH-N 3.45Å; Y240-N390 PolarHBondContact OH-OD1 3.01Å; Y240-S393 WeakPolarHBondContact CE2-OG 3.36Å; Y240-S393 VanDerWaalsContact CZ-OG 3.24Å; Y240-S393 WeakPolarHBondContact OH-CB 3.35Å; Y240-S393 PolarHBondContact OH-OG 3.08Å; Y240-M438 VanDerWaalsContact CA-CE 3.45Å; Y240-M438 HydrophobicContact CD2-CE 3.66Å; Y240-M438 HydrophobicContact CG-CE 4.14Å
241	Y	88.3	Confident	85.8	Confident	37 Å²	37	32.7 Å²	32.7	15%	0.145	17%	0.165	C	C	.	.	H	α-helix	trans	-64.5	-37.5	175.6	-75.6	-73.7	0	0	0	112.5	S65 L237 A238 A245	S65-Y241 VanDerWaalsContact CB-O 3.29Å; S65-Y241 WeakPolarHBondContact CB-O 3.49Å; S65-Y241 PolarHBondContact OG-O 3.36Å; L237-Y241 VanDerWaalsContact O-CD2 3.24Å; L237-Y241 WeakPolarHBondContact O-CD2 3.32Å; L237-Y241 PolarHBondContact O-N 3.35Å; L237-Y241 VanDerWaalsContact O-N 3.16Å; A238-Y241 PolarHBondContact O-N 2.89Å; Y241-A245 PolarHBondContact O-N 3.26Å
242	G	92.6	Very high	86.8	Confident	0 Å²	0	30.8 Å²	30.8	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-64.9	-51.8	177.5	0	0	0	0	0	112.6	A238 F239 Y240 Y244 A245 Y246	A238-G242 PolarHBondContact O-N 3.07Å; F239-G242 PolarHBondContact O-N 3.43Å; Y240-G242 VanDerWaalsContact C-N 3.33Å; Y240-G242 PolarHBondContact O-N 3.49Å; G242-Y244 VanDerWaalsContact C-N 3.26Å; G242-Y244 PolarHBondContact O-N 2.84Å; G242-A245 WeakPolarHBondContact O-CB 3.41Å; G242-A245 PolarHBondContact O-N 2.8Å; G242-Y246 WeakPolarHBondContact O-CD2 3.46Å; G242-Y246 PolarHBondContact O-N 2.99Å
243	M	91.1	Very high	87.6	Confident	0 Å²	0	23.8 Å²	23.8	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-64.8	-29.5	179.9	-66.8	-64.8	-66.9	0	0	112.3	C86 L89 F239 Y246 A247 W397 F431 T434 M438	C86-M243 HydrophobicContact CB-CG 4.49Å; C86-M243 HydrophobicContact CB-SD 3.88Å; L89-M243 HydrophobicContact CB-CE 4.27Å; L89-M243 HydrophobicContact CB-SD 4.12Å; F239-M243 VanDerWaalsContact O-CB 3.27Å; F239-M243 WeakPolarHBondContact O-CB 3.38Å; F239-M243 WeakPolarHBondContact O-CG 3.28Å; F239-M243 PolarHBondContact O-N 3.18Å; M243-Y246 PolarHBondContact O-N 3.03Å; M243-A247 PolarHBondContact O-N 3.49Å; M243-W397 HydrophobicContact CB-CH2 3.98Å; M243-W397 HydrophobicContact CB-CZ2 3.6Å; M243-W397 HydrophobicContact CE-CH2 3.45Å; M243-W397 VanDerWaalsContact CE-CH2 3.45Å; M243-W397 HydrophobicContact CE-CZ2 4.24Å; M243-W397 HydrophobicContact CE-CZ3 3.9Å; M243-F431 HydrophobicContact CE-CE2 4.29Å; M243-T434 HydrophobicContact CE-CG2 4.32Å; M243-M438 HydrophobicContact CB-CE 4.42Å; M243-M438 HydrophobicContact CG-SD 4.41Å
244	Y	88.4	Confident	87.9	Confident	24 Å²	24	19.4 Å²	19.4	9%	0.094	9%	0.089	C	C	.	.	H	α-helix	trans	-59.5	-44.9	170.3	172.1	-103.4	0	0	0	111.9	V141 Y240 G242 Y246 A247 L389	V141-Y244 VanDerWaalsContact CG1-OH 3.26Å; V141-Y244 WeakPolarHBondContact CG1-OH 3.43Å; Y240-Y244 PolarHBondContact O-N 3.14Å; Y240-Y244 VanDerWaalsContact O-N 3.09Å; G242-Y244 VanDerWaalsContact C-N 3.26Å; G242-Y244 PolarHBondContact O-N 2.84Å; Y244-Y246 VanDerWaalsContact C-N 3.28Å; Y244-Y246 PolarHBondContact O-N 3.08Å; Y244-A247 WeakPolarHBondContact O-CB 3.45Å; Y244-A247 PolarHBondContact O-N 3.13Å; Y244-L389 HydrophobicContact CD1-CD2 4.41Å; Y244-L389 HydrophobicContact CD2-CD2 3.57Å; Y244-L389 HydrophobicContact CE1-CD2 4.09Å; Y244-L389 HydrophobicContact CE2-CD2 3.19Å; Y244-L389 HydrophobicContact CG-CD2 4.18Å; Y244-L389 VanDerWaalsContact CZ-CD2 3.5Å
245	A	91.8	Very high	88	Confident	2 Å²	2	12.9 Å²	12.9	2%	0.017	6%	0.064	C	C	.	.	H	α-helix	trans	-66.5	-28.9	-178.1	0	0	0	0	0	113.5	W83 Y241 G242 Y281	W83-A245 HydrophobicContact CH2-CB 3.54Å; W83-A245 HydrophobicContact CZ3-CB 3.55Å; Y241-A245 PolarHBondContact O-N 3.26Å; G242-A245 WeakPolarHBondContact O-CB 3.41Å; G242-A245 PolarHBondContact O-N 2.8Å; A245-Y281 HydrophobicContact CB-CE2 4.03Å; A245-Y281 VanDerWaalsContact O-CE2 3.25Å; A245-Y281 WeakPolarHBondContact O-CE2 3.43Å; A245-Y281 PolarHBondContact O-OH 3.17Å
246	Y	92.4	Very high	88	Confident	0 Å²	0	10.9 Å²	10.9	0%	0	5%	0.054	C	C	.	.	T	Hydrogen-bonded Turn	trans	-88	0.8	177	-75.2	-80.1	0	0	0	114.2	W83 C86 S90 G242 M243 Y244 W249 M274 V277 Y281	W83-Y246 HydrophobicContact CE3-CD2 4.48Å; W83-Y246 AromaticContact CE3-CE2 3.6Å; W83-Y246 HydrophobicContact CE3-CE2 3.6Å; W83-Y246 HydrophobicContact CZ3-CE2 4.01Å; W83-Y246 WeakPolarHBondContact O-CE2 3.41Å; W83-Y246 PolarHBondContact O-OH 3.35Å; W83-Y246 VanDerWaalsContact O-OH 3.13Å; C86-Y246 HydrophobicContact CB-CD2 3.69Å; C86-Y246 HydrophobicContact CB-CE2 3.77Å; S90-Y246 WeakPolarHBondContact OG-CB 3.49Å; G242-Y246 WeakPolarHBondContact O-CD2 3.46Å; G242-Y246 PolarHBondContact O-N 2.99Å; M243-Y246 PolarHBondContact O-N 3.03Å; Y244-Y246 VanDerWaalsContact C-N 3.28Å; Y244-Y246 PolarHBondContact O-N 3.08Å; Y246-W249 VanDerWaalsContact O-CD1 3.27Å; Y246-M274 HydrophobicContact CD1-CE 4.15Å; Y246-V277 HydrophobicContact CD1-CG1 3.8Å; Y246-V277 HydrophobicContact CE1-CG1 3.77Å; Y246-Y281 AromaticContact CD1-CD2 3.99Å; Y246-Y281 HydrophobicContact CD1-CD2 3.99Å; Y246-Y281 HydrophobicContact CD1-CE2 4.05Å; Y246-Y281 HydrophobicContact CD2-CD2 4.28Å; Y246-Y281 HydrophobicContact CD2-CE2 4.5Å; Y246-Y281 AromaticContact CE1-CD2 3.53Å; Y246-Y281 HydrophobicContact CE1-CD2 3.53Å; Y246-Y281 HydrophobicContact CE1-CE2 4.06Å; Y246-Y281 HydrophobicContact CE1-CG 4.36Å; Y246-Y281 AromaticContact CE2-CD2 3.86Å; Y246-Y281 HydrophobicContact CE2-CD2 3.86Å; Y246-Y281 HydrophobicContact CG-CD2 4.33Å; Y246-Y281 HydrophobicContact CG-CE2 4.27Å; Y246-Y281 AromaticContact CZ-CD2 3.45Å; Y246-Y281 VanDerWaalsContact CZ-CD2 3.45Å; Y246-Y281 WeakPolarHBondContact OH-CB 3.3Å
247	A	86.9	Confident	87.8	Confident	18 Å²	18	12 Å²	12	15%	0.149	6%	0.057	C	C	.	.	T	Hydrogen-bonded Turn	trans	-70.6	134.4	-178.1	0	0	0	0	0	111.9	M243 Y244	M243-A247 PolarHBondContact O-N 3.49Å; Y244-A247 WeakPolarHBondContact O-CB 3.45Å; Y244-A247 PolarHBondContact O-N 3.13Å
248	G	87.4	Confident	87.7	Confident	0 Å²	0	10.3 Å²	10.3	0%	0	5%	0.048	C	C	.	.	T	Hydrogen-bonded Turn	trans	135.7	-11.3	174.2	0	0	0	0	0	114.9	F250 Y251	G248-F250 PolarHBondContact O-N 3.38Å; G248-Y251 VanDerWaalsContact CA-CD2 3.49Å; G248-Y251 WeakPolarHBondContact O-CD2 3.44Å; G248-Y251 PolarHBondContact O-N 3.06Å
249	W	91	Very high	87.5	Confident	1 Å²	1	10.3 Å²	10.3	0%	0.004	5%	0.048	C	C	.	.	T	Hydrogen-bonded Turn	trans	-57.3	-22.9	179.3	50	-104.5	0	0	0	114.6	I57 G93 A94 Y97 Y246 M274 I400 F431	I57-W249 HydrophobicContact CD1-CB 3.85Å; G93-W249 VanDerWaalsContact C-CZ3 3.44Å; G93-W249 WeakPolarHBondContact O-CH2 3.35Å; G93-W249 WeakPolarHBondContact O-CZ3 3.45Å; A94-W249 HydrophobicContact CB-CB 3.83Å; A94-W249 HydrophobicContact CB-CD2 3.64Å; A94-W249 HydrophobicContact CB-CE3 3.57Å; A94-W249 HydrophobicContact CB-CG 3.77Å; A94-W249 HydrophobicContact CB-CZ3 4.34Å; Y97-W249 HydrophobicContact CD1-CZ3 4.04Å; Y97-W249 AromaticContact CD2-CH2 3.53Å; Y97-W249 HydrophobicContact CD2-CH2 3.53Å; Y97-W249 AromaticContact CD2-CZ3 3.36Å; Y97-W249 HydrophobicContact CD2-CZ3 3.36Å; Y97-W249 HydrophobicContact CE1-CZ3 4.49Å; Y97-W249 AromaticContact CE2-CH2 3.66Å; Y97-W249 HydrophobicContact CE2-CH2 3.66Å; Y97-W249 AromaticContact CE2-CZ3 3.87Å; Y97-W249 HydrophobicContact CE2-CZ3 3.87Å; Y97-W249 HydrophobicContact CG-CE3 4.48Å; Y97-W249 HydrophobicContact CG-CH2 4.1Å; Y97-W249 AromaticContact CG-CZ3 3.45Å; Y97-W249 HydrophobicContact CG-CZ3 3.45Å; Y97-W249 VanDerWaalsContact CG-CZ3 3.45Å; Y246-W249 VanDerWaalsContact O-CD1 3.27Å; W249-M274 HydrophobicContact CB-CG 4.47Å; W249-M274 HydrophobicContact CB-SD 3.64Å; W249-M274 HydrophobicContact CG-SD 4.15Å; W249-I400 HydrophobicContact CH2-CG2 4.41Å; W249-F431 HydrophobicContact CH2-CE1 4.24Å; W249-F431 HydrophobicContact CH2-CZ 4.12Å; W249-F431 HydrophobicContact CZ2-CE1 4.21Å; W249-F431 HydrophobicContact CZ2-CE2 4.31Å; W249-F431 AromaticContact CZ2-CZ 3.63Å; W249-F431 HydrophobicContact CZ2-CZ 3.63Å
250	F	89.3	Confident	87.4	Confident	9 Å²	9	13.2 Å²	13.2	4%	0.039	6%	0.062	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.1	-8.6	179.6	48.2	-107	0	0	0	114.3	Y97 G248 L252 N253 F254 I400	Y97-F250 HydrophobicContact CD1-CB 3.82Å; Y97-F250 HydrophobicContact CE1-CB 3.83Å; Y97-F250 HydrophobicContact CG-CB 4.5Å; G248-F250 PolarHBondContact O-N 3.38Å; F250-L252 VanDerWaalsContact C-N 3.26Å; F250-L252 PolarHBondContact O-N 3.34Å; F250-N253 WeakPolarHBondContact O-CB 3.16Å; F250-N253 PolarHBondContact O-N 3.18Å; F250-N253 VanDerWaalsContact O-N 3.09Å; F250-F254 HydrophobicContact CB-CE2 4.34Å; F250-F254 HydrophobicContact CD2-CD2 4.44Å; F250-F254 AromaticContact CD2-CE2 3.64Å; F250-F254 HydrophobicContact CD2-CE2 3.64Å; F250-F254 HydrophobicContact CD2-CZ 4.44Å; F250-F254 HydrophobicContact CE2-CE2 4.46Å; F250-F254 HydrophobicContact CG-CE2 4.4Å; F250-F254 VanDerWaalsContact O-CD2 3.25Å; F250-F254 WeakPolarHBondContact O-CD2 3.48Å; F250-F254 VanDerWaalsContact O-CE2 3.32Å; F250-F254 WeakPolarHBondContact O-CE2 3.47Å; F250-I400 HydrophobicContact CD1-CD1 4.16Å; F250-I400 HydrophobicContact CE1-CD1 3.76Å; F250-I400 HydrophobicContact CZ-CD1 4.5Å
251	Y	86.3	Confident	87.5	Confident	26 Å²	26	18 Å²	18	10%	0.102	9%	0.088	C	C	.	.	G	3₁₀ helix	trans	-63	-31.2	-171	-81.6	-65.4	0	0	0	113.8	T56 R135 G248 N253 F254 A337	T56-Y251 HydrophobicContact CG2-CD2 3.66Å; T56-Y251 HydrophobicContact CG2-CE2 4.1Å; T56-Y251 HydrophobicContact CG2-CG 4.11Å; T56-Y251 WeakPolarHBondContact OG1-CD2 3.26Å; R135-Y251 VanDerWaalsContact NH1-CZ 3.32Å; R135-Y251 PolarHBondContact NH1-OH 3.44Å; G248-Y251 VanDerWaalsContact CA-CD2 3.49Å; G248-Y251 WeakPolarHBondContact O-CD2 3.44Å; G248-Y251 PolarHBondContact O-N 3.06Å; Y251-N253 PolarHBondContact O-N 3.25Å; Y251-F254 HydrophobicContact CD1-CD2 4.4Å; Y251-F254 WeakPolarHBondContact O-CB 3.27Å; Y251-F254 PolarHBondContact O-N 2.95Å; Y251-F254 VanDerWaalsContact O-N 3.12Å; Y251-A337 HydrophobicContact CD1-CB 3.33Å; Y251-A337 HydrophobicContact CE1-CB 3.82Å; Y251-A337 HydrophobicContact CG-CB 4.32Å
252	L	85.9	Confident	87.6	Confident	0 Å²	0	17.3 Å²	17.3	0%	0	9%	0.088	C	C	.	.	G	3₁₀ helix	trans	-62.3	-31.9	177.6	-168.4	62.1	0	0	0	111.9	V44 I53 F250 F254 V255 T256 V259 I266 A269	V44-L252 HydrophobicContact CG1-CD1 4.02Å; I53-L252 HydrophobicContact CD1-CB 4.04Å; I53-L252 HydrophobicContact CD1-CD2 3.84Å; I53-L252 HydrophobicContact CG1-CB 4.04Å; F250-L252 VanDerWaalsContact C-N 3.26Å; F250-L252 PolarHBondContact O-N 3.34Å; L252-F254 PolarHBondContact O-N 3.43Å; L252-V255 HydrophobicContact CD1-CG2 4.21Å; L252-V255 WeakPolarHBondContact O-CG2 3.36Å; L252-V255 PolarHBondContact O-N 3.35Å; L252-T256 PolarHBondContact O-N 2.84Å; L252-V259 HydrophobicContact CD1-CG2 3.79Å; L252-V259 HydrophobicContact CG-CG2 4.22Å; L252-I266 HydrophobicContact CD2-CB 4.41Å; L252-I266 HydrophobicContact CD2-CG1 4.09Å; L252-I266 HydrophobicContact CG-CG1 4.39Å; L252-A269 HydrophobicContact CD2-CB 3.83Å
253	N	88.5	Confident	87.5	Confident	0 Å²	0	21 Å²	21	0%	0	11%	0.105	C	C	.	.	G	3₁₀ helix	trans	-67.8	-19.4	178	-65.9	81.5	0	0	0	113.7	Y97 G109 Y113 F250 Y251 V255 T256	Y97-N253 HydrophobicContact CD1-CB 4.31Å; Y97-N253 PolarHBondContact O-ND2 3.15Å; G109-N253 PolarHBondContact N-O 3.06Å; Y113-N253 HydrophobicContact CE2-CB 4.43Å; Y113-N253 WeakPolarHBondContact OH-CB 3.22Å; Y113-N253 PolarHBondContact OH-ND2 3.35Å; F250-N253 WeakPolarHBondContact O-CB 3.16Å; F250-N253 PolarHBondContact O-N 3.18Å; F250-N253 VanDerWaalsContact O-N 3.09Å; Y251-N253 PolarHBondContact O-N 3.25Å; N253-V255 VanDerWaalsContact C-N 3.29Å; N253-T256 WeakPolarHBondContact CA-OG1 3.26Å; N253-T256 PolarHBondContact O-OG1 2.88Å
254	F	84.1	Confident	87.5	Confident	1 Å²	1	29 Å²	29	0%	0.004	14%	0.14	C	C	.	.	G	3₁₀ helix	trans	-74.9	-24.1	176	-69.5	-89.6	0	0	0	112.4	S107 G108 H110 F250 Y251 L252 A337 L341	S107-F254 WeakPolarHBondContact CB-O 3.18Å; G108-F254 PolarHBondContact N-O 3.33Å; G108-F254 VanDerWaalsContact N-O 3.12Å; G108-F254 WeakPolarHBondContact O-CD1 3.22Å; G108-F254 WeakPolarHBondContact O-CE1 3.45Å; H110-F254 AromaticContact CD2-CE1 3.94Å; H110-F254 AromaticContact CD2-CZ 3.92Å; H110-F254 AromaticContact CE1-CE1 3.61Å; H110-F254 AromaticContact CE1-CZ 3.11Å; H110-F254 WeakPolarHBondContact CE1-CZ 3.43Å; H110-F254 AromaticContact CG-CZ 3.82Å; H110-F254 AromaticContact ND1-CZ 3.37Å; H110-F254 WeakPolarHBondContact ND1-CZ 3.1Å; H110-F254 AromaticContact NE2-CE1 3.45Å; H110-F254 WeakPolarHBondContact NE2-CE1 3.41Å; H110-F254 AromaticContact NE2-CZ 3.46Å; H110-F254 WeakPolarHBondContact NE2-CZ 3.38Å; F250-F254 HydrophobicContact CB-CE2 4.34Å; F250-F254 HydrophobicContact CD2-CD2 4.44Å; F250-F254 AromaticContact CD2-CE2 3.64Å; F250-F254 HydrophobicContact CD2-CE2 3.64Å; F250-F254 HydrophobicContact CD2-CZ 4.44Å; F250-F254 HydrophobicContact CE2-CE2 4.46Å; F250-F254 HydrophobicContact CG-CE2 4.4Å; F250-F254 VanDerWaalsContact O-CD2 3.25Å; F250-F254 WeakPolarHBondContact O-CD2 3.48Å; F250-F254 VanDerWaalsContact O-CE2 3.32Å; F250-F254 WeakPolarHBondContact O-CE2 3.47Å; Y251-F254 HydrophobicContact CD1-CD2 4.4Å; Y251-F254 WeakPolarHBondContact O-CB 3.27Å; Y251-F254 PolarHBondContact O-N 2.95Å; Y251-F254 VanDerWaalsContact O-N 3.12Å; L252-F254 PolarHBondContact O-N 3.43Å; F254-A337 HydrophobicContact CB-CB 4.4Å; F254-L341 HydrophobicContact CD1-CB 4.07Å; F254-L341 HydrophobicContact CD1-CD1 4.36Å; F254-L341 HydrophobicContact CD1-CD2 4.28Å; F254-L341 HydrophobicContact CD1-CG 4.49Å; F254-L341 HydrophobicContact CE1-CD1 4.23Å; F254-L341 HydrophobicContact CE1-CD2 3.95Å; F254-L341 HydrophobicContact CE1-CG 4.49Å
255	V	82.8	Confident	87.7	Confident	1 Å²	1	28.5 Å²	28.5	1%	0.006	14%	0.139	C	C	.	.	G	3₁₀ helix	trans	-115.2	24.7	-176.1	-62.6	0	0	0	0	111.7	L252 N253 E257 E258 V259 F336 R340	L252-V255 HydrophobicContact CD1-CG2 4.21Å; L252-V255 WeakPolarHBondContact O-CG2 3.36Å; L252-V255 PolarHBondContact O-N 3.35Å; N253-V255 VanDerWaalsContact C-N 3.29Å; V255-E257 PolarHBondContact O-N 3.43Å; V255-E257 VanDerWaalsContact O-N 3.15Å; V255-E258 WeakPolarHBondContact O-CA 3.35Å; V255-E258 WeakPolarHBondContact O-CB 3.49Å; V255-E258 PolarHBondContact O-N 3.1Å; V255-V259 PolarHBondContact O-N 3.49Å; V255-F336 HydrophobicContact CG1-CE1 4.05Å; V255-R340 HydrophobicContact CG1-CB 4.43Å; V255-R340 HydrophobicContact CG1-CG 4.01Å
256	T	84.1	Confident	87.7	Confident	1 Å²	1	28.4 Å²	28.4	1%	0.006	14%	0.139	C	C	.	.	G	3₁₀ helix	trans	-52	-38	-176.6	-58.5	0	0	0	0	113	L252 N253 E258 V259 P262 I266	L252-T256 PolarHBondContact O-N 2.84Å; N253-T256 WeakPolarHBondContact CA-OG1 3.26Å; N253-T256 PolarHBondContact O-OG1 2.88Å; T256-E258 PolarHBondContact O-N 2.94Å; T256-V259 PolarHBondContact O-N 2.98Å; T256-P262 HydrophobicContact CG2-CB 4.4Å; T256-I266 HydrophobicContact CG2-CD1 3.91Å
257	E	81.5	Confident	87.8	Confident	46 Å²	46	29 Å²	29	22%	0.215	14%	0.142	C	C	.	.	G	3₁₀ helix	trans	-67.1	-24.1	178.3	-67.2	168	-164.9	0	0	113.1	R42 S107 V255 R347	R42-E257 WeakPolarHBondContact CG-O 3.48Å; S107-E257 PolarHBondContact N-OE1 3.47Å; S107-E257 WeakPolarHBondContact OG-CB 3.35Å; S107-E257 VanDerWaalsContact OG-CG 3.22Å; S107-E257 WeakPolarHBondContact OG-CG 3.33Å; S107-E257 PolarHBondContact OG-N 2.98Å; V255-E257 PolarHBondContact O-N 3.43Å; V255-E257 VanDerWaalsContact O-N 3.15Å; E257-R347 IonicContact OE1-NH2 2.68Å; E257-R347 PolarHBondContact OE1-NH2 3.3Å; E257-R347 IonicContact OE2-NH1 3.95Å; E257-R347 IonicContact OE2-NH2 2.62Å
258	E	81.9	Confident	88.2	Confident	10 Å²	10	32.1 Å²	32.1	5%	0.047	16%	0.156	C	C	.	.	G	3₁₀ helix	trans	-89.1	-9.7	178.4	-59.6	-176.8	-137.2	0	0	112.7	L40 R42 K43 V44 V255 T256 R340	L40-E258 HydrophobicContact CB-CG 4.36Å; R42-E258 CarbonylContact C-O 3.3Å; R42-E258 WeakPolarHBondContact CA-O 3.28Å; K43-E258 PolarHBondContact N-O 3.01Å; V44-E258 HydrophobicContact CG2-CB 4.03Å; V44-E258 PolarHBondContact N-O 2.94Å; V255-E258 WeakPolarHBondContact O-CA 3.35Å; V255-E258 WeakPolarHBondContact O-CB 3.49Å; V255-E258 PolarHBondContact O-N 3.1Å; T256-E258 PolarHBondContact O-N 2.94Å; E258-R340 IonicContact OE1-CZ 2.73Å; E258-R340 IonicContact OE1-NE 3.71Å; E258-R340 PolarHBondContact OE1-NE 3.43Å; E258-R340 IonicContact OE1-NH2 2.69Å; E258-R340 IonicContact OE2-NH2 3.17Å
259	V	86.9	Confident	88.4	Confident	0 Å²	0	32.1 Å²	32.1	0%	0	16%	0.156	C	C	.	.	B	Isolated β-bridge	trans	-78.9	131.6	-178.4	179.2	0	0	0	0	111.5	V44 L252 V255 T256 P262 T265 I266	V44-V259 HydrophobicContact CB-CG2 4.16Å; V44-V259 HydrophobicContact CG1-CG2 4.16Å; L252-V259 HydrophobicContact CD1-CG2 3.79Å; L252-V259 HydrophobicContact CG-CG2 4.22Å; V255-V259 PolarHBondContact O-N 3.49Å; T256-V259 PolarHBondContact O-N 2.98Å; V259-P262 HydrophobicContact CB-CG 4.3Å; V259-P262 HydrophobicContact CG1-CG 4.44Å; V259-T265 HydrophobicContact CG1-CG2 3.62Å; V259-I266 HydrophobicContact CG1-CG1 4.2Å
260	E	87.6	Confident	88.5	Confident	96 Å²	96	32 Å²	32	45%	0.449	16%	0.156	S	C	.	.	S	Bend	trans	-76.3	128.3	172.4	-172.1	179.6	-172	0	0	110.2	V44 T265	V44-E260 PolarHBondContact O-N 2.77Å; E260-T265 VanDerWaalsContact O-CB 3.23Å; E260-T265 WeakPolarHBondContact O-CB 3.19Å; E260-T265 PolarHBondContact O-OG1 2.76Å
261	N	89.1	Confident	88.8	Confident	107 Å²	107	34 Å²	34	57%	0.572	17%	0.17	S	C	*	.	S	Bend	trans	46.2	64	-177.2	-62.6	-39.1	0	0	0	113.8	E263 K264 T265	N261-E263 PolarHBondContact O-N 2.87Å; N261-K264 PolarHBondContact O-N 2.71Å; N261-K264 VanDerWaalsContact O-N 3.08Å; N261-T265 WeakPolarHBondContact O-CB 3.45Å; N261-T265 PolarHBondContact O-N 2.93Å; N261-T265 PolarHBondContact O-OG1 2.86Å
262	P	89.4	Confident	89.2	Confident	22 Å²	22	35.8 Å²	35.8	14%	0.143	18%	0.181	C	C	.	.	H	α-helix	trans	-52.3	-34.5	-171.9	-27.8	34.9	0	0	0	114.7	T256 V259 K264 I266	T256-P262 HydrophobicContact CG2-CB 4.4Å; V259-P262 HydrophobicContact CB-CG 4.3Å; V259-P262 HydrophobicContact CG1-CG 4.44Å; P262-K264 VanDerWaalsContact C-N 3.29Å; P262-K264 PolarHBondContact O-N 3.38Å; P262-I266 HydrophobicContact CB-CD1 3.82Å; P262-I266 HydrophobicContact CB-CG1 4.36Å; P262-I266 VanDerWaalsContact O-CB 3.3Å; P262-I266 WeakPolarHBondContact O-CB 3.41Å; P262-I266 WeakPolarHBondContact O-CG1 3.34Å; P262-I266 PolarHBondContact O-N 3.27Å
263	E	91.1	Very high	89.6	Confident	77 Å²	77	35.8 Å²	35.8	36%	0.36	18%	0.181	S	C	.	.	H	α-helix	trans	-60.7	-34.3	-178.2	-59.1	-175.7	180	0	0	113.9	K105 N261 P267 P420	K105-E263 WeakPolarHBondContact CE-OE1 3.34Å; K105-E263 IonicContact NZ-OE1 3.54Å; K105-E263 PolarHBondContact NZ-OE1 3.21Å; N261-E263 PolarHBondContact O-N 2.87Å; E263-P267 WeakPolarHBondContact O-CD 3.27Å; E263-P267 WeakPolarHBondContact O-CG 3.25Å; E263-P420 HydrophobicContact CB-CB 3.96Å; E263-P420 HydrophobicContact CB-CG 4.43Å; E263-P420 HydrophobicContact CG-CB 3.83Å; E263-P420 HydrophobicContact CG-CG 3.74Å
264	K	91.1	Very high	89.9	Confident	168 Å²	168	35.9 Å²	35.9	73%	0.73	18%	0.181	S	C	*	.	H	α-helix	trans	-100.1	-41.6	178.6	-65.3	-176.8	179.8	180	0	111.1	N261 P262 L268	N261-K264 PolarHBondContact O-N 2.71Å; N261-K264 VanDerWaalsContact O-N 3.08Å; P262-K264 VanDerWaalsContact C-N 3.29Å; P262-K264 PolarHBondContact O-N 3.38Å; K264-L268 VanDerWaalsContact O-CB 3.23Å; K264-L268 WeakPolarHBondContact O-CB 3.36Å; K264-L268 PolarHBondContact O-N 2.79Å
265	T	92.6	Very high	90.4	Very high	14 Å²	14	38.2 Å²	38.2	9%	0.086	20%	0.201	C	C	.	.	H	α-helix	trans	-69.6	-42.5	-172.6	-61.3	0	0	0	0	112.5	L46 V259 E260 N261 A269	L46-T265 HydrophobicContact CB-CG2 4.26Å; L46-T265 HydrophobicContact CD1-CG2 4.2Å; V259-T265 HydrophobicContact CG1-CG2 3.62Å; E260-T265 VanDerWaalsContact O-CB 3.23Å; E260-T265 WeakPolarHBondContact O-CB 3.19Å; E260-T265 PolarHBondContact O-OG1 2.76Å; N261-T265 WeakPolarHBondContact O-CB 3.45Å; N261-T265 PolarHBondContact O-N 2.93Å; N261-T265 PolarHBondContact O-OG1 2.86Å; T265-A269 WeakPolarHBondContact O-CB 3.46Å; T265-A269 PolarHBondContact O-N 2.94Å
266	I	92.6	Very high	90.9	Very high	0 Å²	0	41.6 Å²	41.6	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-65.5	-53.6	-176.9	-64.9	174.4	0	0	0	111.3	A98 L252 T256 V259 P262 L268 A269 I270	A98-I266 HydrophobicContact CB-CG2 4.32Å; L252-I266 HydrophobicContact CD2-CB 4.41Å; L252-I266 HydrophobicContact CD2-CG1 4.09Å; L252-I266 HydrophobicContact CG-CG1 4.39Å; T256-I266 HydrophobicContact CG2-CD1 3.91Å; V259-I266 HydrophobicContact CG1-CG1 4.2Å; P262-I266 HydrophobicContact CB-CD1 3.82Å; P262-I266 HydrophobicContact CB-CG1 4.36Å; P262-I266 VanDerWaalsContact O-CB 3.3Å; P262-I266 WeakPolarHBondContact O-CB 3.41Å; P262-I266 WeakPolarHBondContact O-CG1 3.34Å; P262-I266 PolarHBondContact O-N 3.27Å; I266-L268 VanDerWaalsContact C-N 3.35Å; I266-L268 PolarHBondContact O-N 3.4Å; I266-A269 PolarHBondContact O-N 3.31Å; I266-I270 HydrophobicContact CG2-CD1 3.72Å; I266-I270 WeakPolarHBondContact O-CB 3.33Å; I266-I270 WeakPolarHBondContact O-CG1 3.48Å; I266-I270 PolarHBondContact O-N 3.25Å
267	P	93.9	Very high	91.4	Very high	12 Å²	12	41.6 Å²	41.6	8%	0.078	22%	0.218	C	C	.	.	H	α-helix	trans	-62	-41.9	-179.4	-22.6	34.4	0	0	0	112.6	A98 T102 E263 I270 C271 F421	A98-P267 HydrophobicContact CB-CB 4.41Å; A98-P267 HydrophobicContact CB-CG 4.35Å; T102-P267 HydrophobicContact CG2-CG 3.98Å; E263-P267 WeakPolarHBondContact O-CD 3.27Å; E263-P267 WeakPolarHBondContact O-CG 3.25Å; P267-I270 PolarHBondContact O-N 3.44Å; P267-C271 PolarHBondContact O-N 3.49Å; P267-C271 PolarHBondContact O-SG 3.39Å; P267-F421 HydrophobicContact CB-CD1 4.46Å; P267-F421 HydrophobicContact CB-CD2 3.76Å; P267-F421 HydrophobicContact CB-CE2 3.83Å; P267-F421 HydrophobicContact CB-CG 4.09Å; P267-F421 HydrophobicContact CB-CZ 4.21Å; P267-F421 HydrophobicContact CG-CB 3.96Å; P267-F421 HydrophobicContact CG-CD1 4.25Å; P267-F421 HydrophobicContact CG-CD2 3.8Å; P267-F421 HydrophobicContact CG-CE2 4.37Å; P267-F421 HydrophobicContact CG-CG 3.74Å
268	L	94.4	Very high	92.1	Very high	83 Å²	83	40.6 Å²	40.6	44%	0.435	22%	0.215	S	C	.	.	H	α-helix	trans	-67.5	-44.5	-178.4	-172.3	64.6	0	0	0	111.8	L46 K264 I266 I270 C271 I272	L46-L268 HydrophobicContact CD1-CB 4.04Å; L46-L268 HydrophobicContact CD1-CD2 3.91Å; L46-L268 HydrophobicContact CD1-CG 4.01Å; L46-L268 HydrophobicContact CD2-CD2 3.51Å; L46-L268 HydrophobicContact CD2-CG 4.34Å; L46-L268 HydrophobicContact CG-CD2 4.37Å; K264-L268 VanDerWaalsContact O-CB 3.23Å; K264-L268 WeakPolarHBondContact O-CB 3.36Å; K264-L268 PolarHBondContact O-N 2.79Å; I266-L268 VanDerWaalsContact C-N 3.35Å; I266-L268 PolarHBondContact O-N 3.4Å; L268-I270 VanDerWaalsContact C-N 3.34Å; L268-I270 PolarHBondContact O-N 3Å; L268-C271 PolarHBondContact O-N 3.47Å; L268-I272 HydrophobicContact CD1-CD1 3.81Å; L268-I272 HydrophobicContact CD1-CG1 4.3Å; L268-I272 HydrophobicContact CG-CD1 3.77Å; L268-I272 WeakPolarHBondContact O-CB 3.38Å; L268-I272 VanDerWaalsContact O-CG1 3.3Å; L268-I272 WeakPolarHBondContact O-CG1 3.28Å; L268-I272 PolarHBondContact O-N 3.08Å; L268-I272 VanDerWaalsContact O-N 3.09Å
269	A	92.8	Very high	92.7	Very high	0 Å²	0	45.2 Å²	45.2	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-59.9	-46	176.3	0	0	0	0	0	111.1	L46 I50 I53 L252 T265 I266 S273	L46-A269 HydrophobicContact CD1-CB 4.04Å; I50-A269 HydrophobicContact CG1-CB 3.98Å; I53-A269 HydrophobicContact CD1-CB 3.92Å; L252-A269 HydrophobicContact CD2-CB 3.83Å; T265-A269 WeakPolarHBondContact O-CB 3.46Å; T265-A269 PolarHBondContact O-N 2.94Å; I266-A269 PolarHBondContact O-N 3.31Å; A269-S273 WeakPolarHBondContact O-CB 3.2Å; A269-S273 PolarHBondContact O-N 3.26Å; A269-S273 PolarHBondContact O-OG 3.03Å
270	I	93.5	Very high	93.1	Very high	0 Å²	0	45.7 Å²	45.7	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-60.9	-50.2	179	-76	170.8	0	0	0	111.7	I53 A94 A98 I266 P267 L268 S273 M274	I53-I270 HydrophobicContact CD1-CG1 3.72Å; A94-I270 HydrophobicContact CB-CG2 3.35Å; A98-I270 HydrophobicContact CB-CD1 3.89Å; I266-I270 HydrophobicContact CG2-CD1 3.72Å; I266-I270 WeakPolarHBondContact O-CB 3.33Å; I266-I270 WeakPolarHBondContact O-CG1 3.48Å; I266-I270 PolarHBondContact O-N 3.25Å; P267-I270 PolarHBondContact O-N 3.44Å; L268-I270 VanDerWaalsContact C-N 3.34Å; L268-I270 PolarHBondContact O-N 3Å; I270-S273 PolarHBondContact O-N 3.43Å; I270-M274 HydrophobicContact CG2-CG 4.37Å; I270-M274 WeakPolarHBondContact O-CB 3.25Å; I270-M274 VanDerWaalsContact O-CG 3.3Å; I270-M274 WeakPolarHBondContact O-CG 3.28Å; I270-M274 PolarHBondContact O-N 3.13Å
271	C	93.9	Very high	93.5	Very high	51 Å²	51	41.1 Å²	41.1	35%	0.345	22%	0.223	S	C	.	.	H	α-helix	trans	-63.4	-46.8	-176.4	-65.8	0	0	0	0	111.8	P267 L268 A275	P267-C271 PolarHBondContact O-N 3.49Å; P267-C271 PolarHBondContact O-SG 3.39Å; L268-C271 PolarHBondContact O-N 3.47Å; C271-A275 WeakPolarHBondContact O-CB 3.31Å; C271-A275 PolarHBondContact O-N 3.3Å
272	I	95.1	Very high	93.9	Very high	63 Å²	63	37.6 Å²	37.6	32%	0.323	21%	0.205	S	C	.	.	H	α-helix	trans	-62.2	-49.2	179.1	-67	171.5	0	0	0	110.1	I50 L268 M274 A275 I276	I50-I272 HydrophobicContact CD1-CB 4.39Å; I50-I272 HydrophobicContact CD1-CD1 4.06Å; I50-I272 HydrophobicContact CD1-CG2 4.11Å; L268-I272 HydrophobicContact CD1-CD1 3.81Å; L268-I272 HydrophobicContact CD1-CG1 4.3Å; L268-I272 HydrophobicContact CG-CD1 3.77Å; L268-I272 WeakPolarHBondContact O-CB 3.38Å; L268-I272 VanDerWaalsContact O-CG1 3.3Å; L268-I272 WeakPolarHBondContact O-CG1 3.28Å; L268-I272 PolarHBondContact O-N 3.08Å; L268-I272 VanDerWaalsContact O-N 3.09Å; I272-M274 PolarHBondContact O-N 3.05Å; I272-A275 PolarHBondContact O-N 3.3Å; I272-I276 HydrophobicContact CG2-CD1 3.67Å; I272-I276 VanDerWaalsContact O-CG1 3.31Å; I272-I276 WeakPolarHBondContact O-CG1 3.49Å; I272-I276 PolarHBondContact O-N 3.15Å
273	S	93.6	Very high	94.2	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-62.7	-44.4	-179.1	-65.3	0	0	0	0	112.3	I50 A269 I270 A275 I276 V277	I50-S273 PolarHBondContact O-OG 2.87Å; A269-S273 WeakPolarHBondContact O-CB 3.2Å; A269-S273 PolarHBondContact O-N 3.26Å; A269-S273 PolarHBondContact O-OG 3.03Å; I270-S273 PolarHBondContact O-N 3.43Å; S273-A275 PolarHBondContact O-N 3.09Å; S273-I276 PolarHBondContact O-N 2.96Å; S273-V277 WeakPolarHBondContact O-CB 3.34Å; S273-V277 WeakPolarHBondContact O-CG2 3.38Å; S273-V277 PolarHBondContact O-N 3.01Å
274	M	94.8	Very high	94.4	Very high	2 Å²	2	36 Å²	36	1%	0.01	20%	0.197	C	C	.	.	H	α-helix	trans	-65.8	-37.4	179.7	-73.9	-54.1	-56.1	0	0	112.7	I57 S90 L91 A94 Y246 W249 I270 I272 T278	I57-M274 HydrophobicContact CD1-SD 3.74Å; S90-M274 VanDerWaalsContact CB-CE 3.49Å; L91-M274 HydrophobicContact CD1-CB 3.85Å; L91-M274 HydrophobicContact CD1-CG 4.17Å; A94-M274 HydrophobicContact CB-CG 4.13Å; Y246-M274 HydrophobicContact CD1-CE 4.15Å; W249-M274 HydrophobicContact CB-CG 4.47Å; W249-M274 HydrophobicContact CB-SD 3.64Å; W249-M274 HydrophobicContact CG-SD 4.15Å; I270-M274 HydrophobicContact CG2-CG 4.37Å; I270-M274 WeakPolarHBondContact O-CB 3.25Å; I270-M274 VanDerWaalsContact O-CG 3.3Å; I270-M274 WeakPolarHBondContact O-CG 3.28Å; I270-M274 PolarHBondContact O-N 3.13Å; I272-M274 PolarHBondContact O-N 3.05Å; M274-T278 VanDerWaalsContact O-CB 3.31Å; M274-T278 WeakPolarHBondContact O-CB 3.47Å; M274-T278 PolarHBondContact O-N 2.9Å; M274-T278 PolarHBondContact O-OG1 2.99Å
275	A	95.2	Very high	94.6	Very high	50 Å²	50	28.1 Å²	28.1	41%	0.413	16%	0.163	S	C	.	.	H	α-helix	trans	-63.4	-49.3	174.7	0	0	0	0	0	111.3	C271 I272 S273 V277 T278 I279	C271-A275 WeakPolarHBondContact O-CB 3.31Å; C271-A275 PolarHBondContact O-N 3.3Å; I272-A275 PolarHBondContact O-N 3.3Å; S273-A275 PolarHBondContact O-N 3.09Å; A275-V277 PolarHBondContact O-N 2.68Å; A275-T278 PolarHBondContact O-N 2.84Å; A275-I279 WeakPolarHBondContact O-CB 3.48Å; A275-I279 WeakPolarHBondContact O-CG1 3.4Å; A275-I279 PolarHBondContact O-N 3.33Å
276	I	93.5	Very high	94.8	Very high	72 Å²	72	28.8 Å²	28.8	37%	0.369	17%	0.167	S	C	.	.	H	α-helix	trans	-58.5	-47.4	178.2	-69	168.2	0	0	0	110.9	I54 L199 I272 S273 G280	I54-I276 HydrophobicContact CD1-CB 4.45Å; I54-I276 HydrophobicContact CD1-CD1 3.99Å; I54-I276 HydrophobicContact CD1-CG2 4.19Å; L199-I276 HydrophobicContact CD2-CG2 4.43Å; I272-I276 HydrophobicContact CG2-CD1 3.67Å; I272-I276 VanDerWaalsContact O-CG1 3.31Å; I272-I276 WeakPolarHBondContact O-CG1 3.49Å; I272-I276 PolarHBondContact O-N 3.15Å; S273-I276 PolarHBondContact O-N 2.96Å; I276-G280 PolarHBondContact O-N 2.84Å
277	V	94.6	Very high	94.9	Very high	0 Å²	0	28.9 Å²	28.9	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-64.5	-45.2	-179.7	173.5	0	0	0	0	111.1	I57 I58 Y246 S273 A275 G280 Y281	I57-V277 HydrophobicContact CB-CG2 4.29Å; I57-V277 HydrophobicContact CD1-CG2 4.29Å; I57-V277 HydrophobicContact CG2-CB 4.49Å; I57-V277 HydrophobicContact CG2-CG1 3.64Å; I57-V277 HydrophobicContact CG2-CG2 4.13Å; I58-V277 HydrophobicContact CD1-CG2 4.05Å; I58-V277 HydrophobicContact CG1-CG2 3.86Å; Y246-V277 HydrophobicContact CD1-CG1 3.8Å; Y246-V277 HydrophobicContact CE1-CG1 3.77Å; S273-V277 WeakPolarHBondContact O-CB 3.34Å; S273-V277 WeakPolarHBondContact O-CG2 3.38Å; S273-V277 PolarHBondContact O-N 3.01Å; A275-V277 PolarHBondContact O-N 2.68Å; V277-G280 PolarHBondContact O-N 2.89Å; V277-Y281 HydrophobicContact CG1-CD1 4.14Å; V277-Y281 HydrophobicContact CG1-CD2 3.8Å; V277-Y281 HydrophobicContact CG1-CE1 3.9Å; V277-Y281 HydrophobicContact CG1-CE2 3.54Å; V277-Y281 HydrophobicContact CG1-CG 4.11Å; V277-Y281 WeakPolarHBondContact O-CB 3.46Å; V277-Y281 VanDerWaalsContact O-CG 3.29Å; V277-Y281 PolarHBondContact O-N 2.85Å
278	T	95.8	Very high	94.9	Very high	26 Å²	26	28.3 Å²	28.3	16%	0.16	16%	0.164	C	C	.	.	H	α-helix	trans	-64.1	-47.5	-176.9	-55.3	0	0	0	0	111.5	M274 A275 Y281 V282	M274-T278 VanDerWaalsContact O-CB 3.31Å; M274-T278 WeakPolarHBondContact O-CB 3.47Å; M274-T278 PolarHBondContact O-N 2.9Å; M274-T278 PolarHBondContact O-OG1 2.99Å; A275-T278 PolarHBondContact O-N 2.84Å; T278-Y281 PolarHBondContact O-N 3.22Å; T278-V282 WeakPolarHBondContact O-CG2 3.33Å; T278-V282 PolarHBondContact O-N 3.22Å; T278-V282 VanDerWaalsContact O-N 3.1Å
279	I	95.8	Very high	94.9	Very high	107 Å²	107	24.5 Å²	24.5	55%	0.549	14%	0.144	S	C	.	.	H	α-helix	trans	-62.1	-47.6	176.1	-66.5	168.1	0	0	0	110	A275 Y281 V282 L283	A275-I279 WeakPolarHBondContact O-CB 3.48Å; A275-I279 WeakPolarHBondContact O-CG1 3.4Å; A275-I279 PolarHBondContact O-N 3.33Å; I279-Y281 PolarHBondContact O-N 2.77Å; I279-V282 PolarHBondContact O-N 3.08Å; I279-L283 HydrophobicContact CG2-CD1 3.67Å; I279-L283 HydrophobicContact CG2-CG 4.24Å; I279-L283 WeakPolarHBondContact O-CB 3.42Å; I279-L283 VanDerWaalsContact O-CG 3.27Å; I279-L283 WeakPolarHBondContact O-CG 3.39Å; I279-L283 PolarHBondContact O-N 2.79Å
280	G	95.1	Very high	94.9	Very high	10 Å²	10	24.8 Å²	24.8	10%	0.103	15%	0.146	C	C	.	.	H	α-helix	trans	-56.8	-48.8	179.2	0	0	0	0	0	112.4	I276 V277 L283 T284	I276-G280 PolarHBondContact O-N 2.84Å; V277-G280 PolarHBondContact O-N 2.89Å; G280-L283 PolarHBondContact O-N 3.37Å; G280-T284 WeakPolarHBondContact O-CB 3.43Å; G280-T284 PolarHBondContact O-N 3.47Å; G280-T284 PolarHBondContact O-OG1 3.36Å
281	Y	96.3	Very high	94.7	Very high	0 Å²	0	26.2 Å²	26.2	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-66.5	-42.8	-178.3	-74.2	3.9	0	0	0	113	I57 I58 I62 W83 A245 Y246 V277 T278 I279 T284 N285	I57-Y281 HydrophobicContact CG2-CE2 4.49Å; I57-Y281 PolarHBondContact O-OH 3.43Å; I58-Y281 WeakPolarHBondContact CA-OH 3.41Å; I58-Y281 HydrophobicContact CG1-CE1 4.1Å; I62-Y281 HydrophobicContact CB-CD1 3.96Å; I62-Y281 HydrophobicContact CB-CE1 3.57Å; I62-Y281 HydrophobicContact CD1-CD1 3.62Å; I62-Y281 HydrophobicContact CD1-CD2 4.21Å; I62-Y281 HydrophobicContact CD1-CE1 4.15Å; I62-Y281 HydrophobicContact CD1-CG 3.64Å; I62-Y281 HydrophobicContact CG1-CD1 3.61Å; I62-Y281 HydrophobicContact CG1-CE1 3.77Å; I62-Y281 HydrophobicContact CG1-CG 4.17Å; I62-Y281 HydrophobicContact CG2-CE1 4.04Å; W83-Y281 AromaticContact CE3-CD2 3.89Å; W83-Y281 HydrophobicContact CE3-CD2 3.89Å; W83-Y281 HydrophobicContact CE3-CG 4.29Å; W83-Y281 HydrophobicContact CH2-CD2 4.47Å; W83-Y281 AromaticContact CZ3-CD2 3.41Å; W83-Y281 HydrophobicContact CZ3-CD2 3.41Å; W83-Y281 VanDerWaalsContact CZ3-CD2 3.41Å; W83-Y281 HydrophobicContact CZ3-CE2 4.04Å; W83-Y281 AromaticContact CZ3-CG 3.96Å; W83-Y281 HydrophobicContact CZ3-CG 3.96Å; A245-Y281 HydrophobicContact CB-CE2 4.03Å; A245-Y281 VanDerWaalsContact O-CE2 3.25Å; A245-Y281 WeakPolarHBondContact O-CE2 3.43Å; A245-Y281 PolarHBondContact O-OH 3.17Å; Y246-Y281 AromaticContact CD1-CD2 3.99Å; Y246-Y281 HydrophobicContact CD1-CD2 3.99Å; Y246-Y281 HydrophobicContact CD1-CE2 4.05Å; Y246-Y281 HydrophobicContact CD2-CD2 4.28Å; Y246-Y281 HydrophobicContact CD2-CE2 4.5Å; Y246-Y281 AromaticContact CE1-CD2 3.53Å; Y246-Y281 HydrophobicContact CE1-CD2 3.53Å; Y246-Y281 HydrophobicContact CE1-CE2 4.06Å; Y246-Y281 HydrophobicContact CE1-CG 4.36Å; Y246-Y281 AromaticContact CE2-CD2 3.86Å; Y246-Y281 HydrophobicContact CE2-CD2 3.86Å; Y246-Y281 HydrophobicContact CG-CD2 4.33Å; Y246-Y281 HydrophobicContact CG-CE2 4.27Å; Y246-Y281 AromaticContact CZ-CD2 3.45Å; Y246-Y281 VanDerWaalsContact CZ-CD2 3.45Å; Y246-Y281 WeakPolarHBondContact OH-CB 3.3Å; V277-Y281 HydrophobicContact CG1-CD1 4.14Å; V277-Y281 HydrophobicContact CG1-CD2 3.8Å; V277-Y281 HydrophobicContact CG1-CE1 3.9Å; V277-Y281 HydrophobicContact CG1-CE2 3.54Å; V277-Y281 HydrophobicContact CG1-CG 4.11Å; V277-Y281 WeakPolarHBondContact O-CB 3.46Å; V277-Y281 VanDerWaalsContact O-CG 3.29Å; V277-Y281 PolarHBondContact O-N 2.85Å; T278-Y281 PolarHBondContact O-N 3.22Å; I279-Y281 PolarHBondContact O-N 2.77Å; Y281-T284 PolarHBondContact O-N 3.25Å; Y281-N285 PolarHBondContact O-N 3.42Å; Y281-N285 PolarHBondContact O-ND2 3.46Å
282	V	96.5	Very high	94.5	Very high	33 Å²	33	23.8 Å²	23.8	20%	0.2	14%	0.138	C	C	.	.	H	α-helix	trans	-62.7	-47	176	173.4	0	0	0	0	109.9	W83 T278 I279 T284 N285 V286	W83-V282 HydrophobicContact CB-CG2 4.19Å; T278-V282 WeakPolarHBondContact O-CG2 3.33Å; T278-V282 PolarHBondContact O-N 3.22Å; T278-V282 VanDerWaalsContact O-N 3.1Å; I279-V282 PolarHBondContact O-N 3.08Å; V282-T284 VanDerWaalsContact C-N 3.35Å; V282-T284 PolarHBondContact O-N 3.15Å; V282-N285 PolarHBondContact O-N 3.46Å; V282-V286 HydrophobicContact CG1-CG2 4.48Å; V282-V286 WeakPolarHBondContact O-CG2 3.25Å; V282-V286 PolarHBondContact O-N 2.97Å
283	L	96.2	Very high	94.3	Very high	66 Å²	66	24.2 Å²	24.2	35%	0.346	14%	0.141	S	C	.	.	H	α-helix	trans	-64.1	-36.5	178.1	-71.4	178.9	0	0	0	112.9	I206 I279 G280 V286 A287	I206-L283 HydrophobicContact CD1-CB 3.7Å; I206-L283 HydrophobicContact CD1-CD1 4.34Å; I206-L283 HydrophobicContact CG1-CB 3.9Å; I206-L283 HydrophobicContact CG2-CB 4.1Å; I206-L283 HydrophobicContact CG2-CD1 4.2Å; I279-L283 HydrophobicContact CG2-CD1 3.67Å; I279-L283 HydrophobicContact CG2-CG 4.24Å; I279-L283 WeakPolarHBondContact O-CB 3.42Å; I279-L283 VanDerWaalsContact O-CG 3.27Å; I279-L283 WeakPolarHBondContact O-CG 3.39Å; I279-L283 PolarHBondContact O-N 2.79Å; G280-L283 PolarHBondContact O-N 3.37Å; L283-V286 PolarHBondContact O-N 3.05Å; L283-A287 WeakPolarHBondContact O-CB 3.35Å; L283-A287 PolarHBondContact O-N 3.09Å
284	T	95.6	Very high	94	Very high	0 Å²	0	25.7 Å²	25.7	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-62.1	-43.2	173.7	-66	0	0	0	0	111.3	I62 I205 G280 Y281 V282 A287 Y288	I62-T284 HydrophobicContact CD1-CG2 4.28Å; I62-T284 HydrophobicContact CG1-CG2 4.04Å; I205-T284 HydrophobicContact CG2-CG2 4.01Å; G280-T284 WeakPolarHBondContact O-CB 3.43Å; G280-T284 PolarHBondContact O-N 3.47Å; G280-T284 PolarHBondContact O-OG1 3.36Å; Y281-T284 PolarHBondContact O-N 3.25Å; V282-T284 VanDerWaalsContact C-N 3.35Å; V282-T284 PolarHBondContact O-N 3.15Å; T284-A287 WeakPolarHBondContact O-CB 3.47Å; T284-A287 PolarHBondContact O-N 3.48Å; T284-Y288 HydrophobicContact CG2-CD2 4.3Å; T284-Y288 HydrophobicContact CG2-CE1 4.32Å; T284-Y288 HydrophobicContact CG2-CE2 3.62Å; T284-Y288 WeakPolarHBondContact O-CD2 3.23Å; T284-Y288 PolarHBondContact O-N 2.88Å
285	N	95.6	Very high	93.6	Very high	1 Å²	1	32.4 Å²	32.4	1%	0.005	19%	0.185	C	C	.	.	H	α-helix	trans	-68.9	-39.9	176.9	-76.3	-87.3	0	0	0	111.8	L80 W83 Y281 V282 A287 Y288 F289	L80-N285 HydrophobicContact CD2-CB 3.61Å; W83-N285 VanDerWaalsContact NE1-CG 3.32Å; W83-N285 PolarHBondContact NE1-ND2 2.85Å; W83-N285 PolarHBondContact NE1-OD1 3.12Å; W83-N285 VanDerWaalsContact NE1-OD1 3.1Å; Y281-N285 PolarHBondContact O-N 3.42Å; Y281-N285 PolarHBondContact O-ND2 3.46Å; V282-N285 PolarHBondContact O-N 3.46Å; N285-A287 VanDerWaalsContact C-N 3.29Å; N285-A287 PolarHBondContact O-N 3.24Å; N285-Y288 PolarHBondContact O-N 3.17Å; N285-F289 HydrophobicContact CB-CE2 4.37Å; N285-F289 WeakPolarHBondContact O-CD2 3.36Å; N285-F289 PolarHBondContact O-N 3.44Å
286	V	95.3	Very high	93.4	Very high	29 Å²	29	31.8 Å²	31.8	18%	0.176	17%	0.173	C	C	.	.	H	α-helix	trans	-56.6	-46.5	171.3	170.3	0	0	0	0	110.3	L80 F221 V282 L283 Y288 F289 T290	L80-V286 HydrophobicContact CD1-CG2 4.11Å; L80-V286 HydrophobicContact CD2-CG2 4.01Å; F221-V286 HydrophobicContact CZ-CG1 3.98Å; V282-V286 HydrophobicContact CG1-CG2 4.48Å; V282-V286 WeakPolarHBondContact O-CG2 3.25Å; V282-V286 PolarHBondContact O-N 2.97Å; L283-V286 PolarHBondContact O-N 3.05Å; V286-Y288 PolarHBondContact O-N 3.35Å; V286-F289 PolarHBondContact O-N 3.15Å; V286-T290 HydrophobicContact CG1-CG2 4.45Å; V286-T290 WeakPolarHBondContact O-CG2 3.44Å; V286-T290 PolarHBondContact O-N 2.89Å
287	A	95.1	Very high	93.3	Very high	2 Å²	2	28.4 Å²	28.4	2%	0.017	16%	0.156	C	C	.	.	H	α-helix	trans	-57.7	-46.8	176.9	0	0	0	0	0	111.9	I205 L283 T284 N285 F289 T290 T291 F307	I205-A287 HydrophobicContact CG2-CB 3.88Å; I205-A287 WeakPolarHBondContact O-CB 3.22Å; L283-A287 WeakPolarHBondContact O-CB 3.35Å; L283-A287 PolarHBondContact O-N 3.09Å; T284-A287 WeakPolarHBondContact O-CB 3.47Å; T284-A287 PolarHBondContact O-N 3.48Å; N285-A287 VanDerWaalsContact C-N 3.29Å; N285-A287 PolarHBondContact O-N 3.24Å; A287-F289 VanDerWaalsContact C-N 3.33Å; A287-F289 PolarHBondContact O-N 3.07Å; A287-T290 PolarHBondContact O-N 3.01Å; A287-T290 VanDerWaalsContact O-N 3.11Å; A287-T290 PolarHBondContact O-OG1 3.32Å; A287-T291 PolarHBondContact O-N 2.91Å; A287-F307 HydrophobicContact CB-CE2 4.32Å; A287-F307 HydrophobicContact CB-CZ 4.43Å; A287-F307 VanDerWaalsContact O-CE2 3.31Å; A287-F307 WeakPolarHBondContact O-CE2 3.25Å
288	Y	94.3	Very high	93	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-54.3	-49.6	174.7	-64.7	-32.1	0	0	0	111.6	P66 I205 T284 N285 V286 T290 T291 I292 V303 F307	P66-Y288 HydrophobicContact CB-CD2 4.41Å; P66-Y288 HydrophobicContact CB-CE2 4.42Å; P66-Y288 HydrophobicContact CG-CD2 4.37Å; P66-Y288 HydrophobicContact CG-CE2 3.95Å; I205-Y288 HydrophobicContact CD1-CE1 4.23Å; I205-Y288 HydrophobicContact CG2-CD1 4.06Å; I205-Y288 HydrophobicContact CG2-CE1 3.65Å; T284-Y288 HydrophobicContact CG2-CD2 4.3Å; T284-Y288 HydrophobicContact CG2-CE1 4.32Å; T284-Y288 HydrophobicContact CG2-CE2 3.62Å; T284-Y288 WeakPolarHBondContact O-CD2 3.23Å; T284-Y288 PolarHBondContact O-N 2.88Å; N285-Y288 PolarHBondContact O-N 3.17Å; V286-Y288 PolarHBondContact O-N 3.35Å; Y288-T290 VanDerWaalsContact C-N 3.26Å; Y288-T290 PolarHBondContact O-N 3.36Å; Y288-T291 PolarHBondContact O-N 3.41Å; Y288-T291 VanDerWaalsContact O-N 3.15Å; Y288-I292 WeakPolarHBondContact O-CG1 3.36Å; Y288-I292 PolarHBondContact O-N 3.1Å; Y288-V303 HydrophobicContact CD1-CG1 4.04Å; Y288-V303 HydrophobicContact CD2-CG1 3.75Å; Y288-V303 HydrophobicContact CE1-CG1 4.09Å; Y288-V303 HydrophobicContact CE2-CG1 3.8Å; Y288-V303 HydrophobicContact CG-CG1 3.88Å; Y288-F307 HydrophobicContact CD1-CB 3.84Å; Y288-F307 AromaticContact CD1-CD2 3.84Å; Y288-F307 HydrophobicContact CD1-CD2 3.84Å; Y288-F307 AromaticContact CD1-CG 3.88Å; Y288-F307 HydrophobicContact CD1-CG 3.88Å; Y288-F307 HydrophobicContact CE1-CB 3.97Å; Y288-F307 HydrophobicContact CE1-CG 4.14Å
289	F	93.8	Very high	92.7	Very high	2 Å²	2	36.9 Å²	36.9	1%	0.009	20%	0.199	C	C	.	.	H	α-helix	trans	-70.5	-13.3	-179.7	-63.3	-56.9	0	0	0	115	L70 V76 S79 L80 N220 F221 N285 V286 A287 L297	L70-F289 HydrophobicContact CD1-CE1 4.22Å; L70-F289 HydrophobicContact CD1-CZ 4.08Å; L70-F289 HydrophobicContact CD2-CE1 3.82Å; L70-F289 HydrophobicContact CD2-CZ 4.18Å; V76-F289 HydrophobicContact CB-CE1 4.49Å; V76-F289 HydrophobicContact CG1-CB 4.14Å; V76-F289 HydrophobicContact CG1-CD1 3.93Å; V76-F289 HydrophobicContact CG1-CD2 3.57Å; V76-F289 HydrophobicContact CG1-CE1 4.19Å; V76-F289 HydrophobicContact CG1-CE2 3.86Å; V76-F289 HydrophobicContact CG1-CG 3.61Å; V76-F289 HydrophobicContact CG1-CZ 4.16Å; V76-F289 HydrophobicContact CG2-CD1 3.9Å; V76-F289 HydrophobicContact CG2-CE1 3.85Å; V76-F289 HydrophobicContact CG2-CG 4.43Å; V76-F289 HydrophobicContact CG2-CZ 4.36Å; S79-F289 WeakPolarHBondContact OG-CE2 3.23Å; L80-F289 HydrophobicContact CD2-CD2 4.28Å; L80-F289 HydrophobicContact CD2-CE2 4.22Å; L80-F289 HydrophobicContact CG-CD2 4.49Å; L80-F289 HydrophobicContact CG-CE2 4.38Å; N220-F289 WeakPolarHBondContact CB-O 3.28Å; N220-F289 PolarHBondContact ND2-O 3.32Å; F221-F289 HydrophobicContact CE1-CB 4.12Å; F221-F289 HydrophobicContact CE2-CB 4.28Å; F221-F289 HydrophobicContact CZ-CB 3.66Å; N285-F289 HydrophobicContact CB-CE2 4.37Å; N285-F289 WeakPolarHBondContact O-CD2 3.36Å; N285-F289 PolarHBondContact O-N 3.44Å; V286-F289 PolarHBondContact O-N 3.15Å; A287-F289 VanDerWaalsContact C-N 3.33Å; A287-F289 PolarHBondContact O-N 3.07Å; F289-L297 HydrophobicContact CD1-CD1 4.38Å; F289-L297 HydrophobicContact CE1-CD1 3.79Å; F289-L297 HydrophobicContact CZ-CD1 4.17Å
290	T	93	Very high	92.1	Very high	7 Å²	7	32.3 Å²	32.3	4%	0.043	18%	0.176	C	C	.	.	H	α-helix	trans	-79.7	-21.4	171.4	59.3	0	0	0	0	113.6	G209 L213 F221 V286 A287 Y288	G209-T290 WeakPolarHBondContact CA-OG1 3.5Å; G209-T290 PolarHBondContact O-OG1 3.4Å; L213-T290 HydrophobicContact CB-CG2 4.09Å; L213-T290 HydrophobicContact CD1-CG2 4.01Å; F221-T290 HydrophobicContact CE2-CG2 3.72Å; F221-T290 HydrophobicContact CZ-CG2 4.18Å; V286-T290 HydrophobicContact CG1-CG2 4.45Å; V286-T290 WeakPolarHBondContact O-CG2 3.44Å; V286-T290 PolarHBondContact O-N 2.89Å; A287-T290 PolarHBondContact O-N 3.01Å; A287-T290 VanDerWaalsContact O-N 3.11Å; A287-T290 PolarHBondContact O-OG1 3.32Å; Y288-T290 VanDerWaalsContact C-N 3.26Å; Y288-T290 PolarHBondContact O-N 3.36Å
291	T	89.6	Confident	91.3	Very high	29 Å²	29	36.6 Å²	36.6	18%	0.178	20%	0.197	C	C	.	.	H	α-helix	trans	-115.4	-42	-171	-58.4	0	0	0	0	112.6	A287 Y288 F307 R310 L311	A287-T291 PolarHBondContact O-N 2.91Å; Y288-T291 PolarHBondContact O-N 3.41Å; Y288-T291 VanDerWaalsContact O-N 3.15Å; T291-F307 HydrophobicContact CG2-CD2 4.07Å; T291-F307 HydrophobicContact CG2-CE2 4.16Å; T291-F307 WeakPolarHBondContact OG1-CE2 3.34Å; T291-R310 HydrophobicContact CG2-CB 3.71Å; T291-L311 HydrophobicContact CG2-CB 4.23Å
292	I	90.9	Very high	90.7	Very high	1 Å²	1	36.7 Å²	36.7	1%	0.005	20%	0.198	C	C	.	.	S	Bend	trans	-113	146.3	179.7	54.5	170.9	0	0	0	110.1	N220 Y288 E296 L297 V303 T306 R310	N220-I292 PolarHBondContact ND2-O 3.4Å; N220-I292 VanDerWaalsContact ND2-O 3.12Å; Y288-I292 WeakPolarHBondContact O-CG1 3.36Å; Y288-I292 PolarHBondContact O-N 3.1Å; I292-E296 HydrophobicContact CB-CG 4.46Å; I292-E296 HydrophobicContact CG2-CG 4.47Å; I292-L297 HydrophobicContact CD1-CB 4.02Å; I292-L297 HydrophobicContact CD1-CD1 4.24Å; I292-L297 HydrophobicContact CD1-CG 4.19Å; I292-V303 HydrophobicContact CD1-CG1 3.95Å; I292-T306 HydrophobicContact CG2-CG2 4.35Å; I292-R310 HydrophobicContact CG2-CG 3.95Å
293	N	89.3	Confident	90.2	Very high	72 Å²	72	35.2 Å²	35.2	39%	0.385	19%	0.189	S	C	.	.			trans	-80.7	166.7	176.4	71.7	25.3	0	0	0	111.4	E295 E296 L297	N293-E295 VanDerWaalsContact C-N 3.31Å; N293-E295 PolarHBondContact O-N 3.31Å; N293-E295 PolarHBondContact OD1-N 3.05Å; N293-E296 PolarHBondContact O-N 3.12Å; N293-E296 WeakPolarHBondContact OD1-CB 3.42Å; N293-E296 PolarHBondContact OD1-N 3.49Å; N293-L297 PolarHBondContact O-N 3.09Å; N293-L297 VanDerWaalsContact O-N 3.09Å
294	A	87.4	Confident	89.8	Confident	30 Å²	30	32.1 Å²	32.1	25%	0.248	17%	0.173	C	C	.	.	H	α-helix	trans	-61.9	-37	-176.1	0	0	0	0	0	113	L70 V76 L298	L70-A294 HydrophobicContact CD2-CB 3.99Å; V76-A294 HydrophobicContact CG2-CB 4.38Å; A294-L298 WeakPolarHBondContact O-CG 3.34Å; A294-L298 PolarHBondContact O-N 3.47Å
295	E	87.9	Confident	89.4	Confident	144 Å²	144	32.5 Å²	32.5	67%	0.673	18%	0.175	S	C	*	.	H	α-helix	trans	-69.1	-43.9	-179.7	-63.7	-175.5	165.5	0	0	111.8	N293 L297 L298 L299	N293-E295 VanDerWaalsContact C-N 3.31Å; N293-E295 PolarHBondContact O-N 3.31Å; N293-E295 PolarHBondContact OD1-N 3.05Å; E295-L297 VanDerWaalsContact C-N 3.33Å; E295-L297 PolarHBondContact O-N 2.94Å; E295-L298 PolarHBondContact O-N 3.43Å; E295-L298 VanDerWaalsContact O-N 3.16Å; E295-L299 WeakPolarHBondContact O-CG 3.48Å; E295-L299 PolarHBondContact O-N 3.46Å
296	E	90	Very high	89	Confident	37 Å²	37	33.6 Å²	33.6	17%	0.173	18%	0.182	C	C	.	.	H	α-helix	trans	-62.3	-40.2	176	-177.5	174.2	-164.8	0	0	111.5	I292 N293 L298 L299 S300 T306 R310	I292-E296 HydrophobicContact CB-CG 4.46Å; I292-E296 HydrophobicContact CG2-CG 4.47Å; N293-E296 PolarHBondContact O-N 3.12Å; N293-E296 WeakPolarHBondContact OD1-CB 3.42Å; N293-E296 PolarHBondContact OD1-N 3.49Å; E296-L298 VanDerWaalsContact C-N 3.29Å; E296-L298 PolarHBondContact O-N 3.05Å; E296-L299 PolarHBondContact O-N 2.96Å; E296-S300 WeakPolarHBondContact O-CB 3.26Å; E296-S300 PolarHBondContact O-N 3.12Å; E296-T306 HydrophobicContact CG-CG2 4.07Å; E296-R310 VanDerWaalsContact CD-NH2 3.31Å; E296-R310 IonicContact OE1-CZ 3.39Å; E296-R310 IonicContact OE1-NE 3.72Å; E296-R310 PolarHBondContact OE1-NE 3.01Å; E296-R310 IonicContact OE1-NH2 3.85Å; E296-R310 PolarHBondContact OE1-NH2 3.27Å; E296-R310 IonicContact OE2-CZ 2.81Å; E296-R310 IonicContact OE2-NE 2.7Å; E296-R310 IonicContact OE2-NH2 3.17Å; E296-R310 PolarHBondContact OE2-NH2 2.99Å
297	L	90.8	Very high	88.8	Confident	0 Å²	0	32.2 Å²	32.2	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-60.1	-40.5	174.5	-168.7	158.2	0	0	0	111.6	P66 K67 L70 F289 I292 N293 E295 S300 V303	P66-L297 HydrophobicContact CB-CD2 4.49Å; K67-L297 HydrophobicContact CB-CD2 4.22Å; L70-L297 HydrophobicContact CB-CD2 4.34Å; L70-L297 HydrophobicContact CD2-CB 4.17Å; L70-L297 HydrophobicContact CD2-CD1 4.23Å; L70-L297 HydrophobicContact CD2-CD2 3.81Å; L70-L297 HydrophobicContact CD2-CG 4.28Å; F289-L297 HydrophobicContact CD1-CD1 4.38Å; F289-L297 HydrophobicContact CE1-CD1 3.79Å; F289-L297 HydrophobicContact CZ-CD1 4.17Å; I292-L297 HydrophobicContact CD1-CB 4.02Å; I292-L297 HydrophobicContact CD1-CD1 4.24Å; I292-L297 HydrophobicContact CD1-CG 4.19Å; N293-L297 PolarHBondContact O-N 3.09Å; N293-L297 VanDerWaalsContact O-N 3.09Å; E295-L297 VanDerWaalsContact C-N 3.33Å; E295-L297 PolarHBondContact O-N 2.94Å; L297-S300 PolarHBondContact O-N 2.83Å; L297-V303 HydrophobicContact CD1-CG1 4.17Å; L297-V303 HydrophobicContact CD2-CG2 4.26Å; L297-V303 HydrophobicContact CG-CG1 3.95Å; L297-V303 HydrophobicContact CG-CG2 4.24Å
298	L	89.8	Confident	88.5	Confident	61 Å²	61	32.1 Å²	32.1	32%	0.319	17%	0.173	S	C	.	.	H	α-helix	trans	-70.7	-31.8	178.1	-67.7	175.1	0	0	0	113.1	K67 L70 Q71 A294 E295 E296	K67-L298 WeakPolarHBondContact CE-O 3.29Å; K67-L298 HydrophobicContact CG-CD2 4.46Å; K67-L298 PolarHBondContact NZ-O 3.37Å; L70-L298 HydrophobicContact CB-CD2 4.19Å; L70-L298 HydrophobicContact CD2-CD2 4.23Å; L70-L298 HydrophobicContact CD2-CG 4.15Å; L70-L298 HydrophobicContact CG-CD2 4.19Å; L70-L298 HydrophobicContact CG-CG 4.47Å; Q71-L298 HydrophobicContact CB-CD2 3.74Å; Q71-L298 HydrophobicContact CG-CD2 4.49Å; A294-L298 WeakPolarHBondContact O-CG 3.34Å; A294-L298 PolarHBondContact O-N 3.47Å; E295-L298 PolarHBondContact O-N 3.43Å; E295-L298 VanDerWaalsContact O-N 3.16Å; E296-L298 VanDerWaalsContact C-N 3.29Å; E296-L298 PolarHBondContact O-N 3.05Å
299	L	87.9	Confident	88.2	Confident	144 Å²	144	36.5 Å²	36.5	75%	0.754	19%	0.193	S	C	*	.	H	α-helix	trans	-78	-27.1	176.3	-68.8	172.3	0	0	0	112.5	E295 E296	E295-L299 WeakPolarHBondContact O-CG 3.48Å; E295-L299 PolarHBondContact O-N 3.46Å; E296-L299 PolarHBondContact O-N 2.96Å
300	S	84.7	Confident	87.9	Confident	10 Å²	10	44 Å²	44	7%	0.07	22%	0.222	C	C	.	.			trans	-64.4	140.3	-179.7	-177.7	0	0	0	0	112.3	K67 E296 L297 A302 V303 T306	K67-S300 WeakPolarHBondContact CD-O 3.25Å; K67-S300 PolarHBondContact NZ-O 3.06Å; E296-S300 WeakPolarHBondContact O-CB 3.26Å; E296-S300 PolarHBondContact O-N 3.12Å; L297-S300 PolarHBondContact O-N 2.83Å; S300-A302 PolarHBondContact OG-N 3.25Å; S300-A302 VanDerWaalsContact OG-N 3.14Å; S300-A302 PolarHBondContact OG-O 2.82Å; S300-V303 PolarHBondContact OG-N 3.18Å; S300-T306 WeakPolarHBondContact CB-OG1 3.5Å; S300-T306 PolarHBondContact OG-OG1 3.23Å
301	N	77.4	Confident	87.7	Confident	100 Å²	100	46.2 Å²	46.2	54%	0.535	23%	0.232	S	C	.	.	S	Bend	trans	-89.6	-23.7	169.3	-74.5	-35.6	0	0	0	112.6	R148	R148-N301 PolarHBondContact NH2-ND2 2.91Å
302	A	83.3	Confident	87.5	Confident	2 Å²	2	46.6 Å²	46.6	2%	0.017	23%	0.233	C	C	.	.	S	Bend	trans	-140.4	84	-176.5	0	0	0	0	0	109.3	Y149 S300 A304 V305 T306	Y149-A302 HydrophobicContact CE1-CB 3.83Å; S300-A302 PolarHBondContact OG-N 3.25Å; S300-A302 VanDerWaalsContact OG-N 3.14Å; S300-A302 PolarHBondContact OG-O 2.82Å; A302-A304 PolarHBondContact O-N 2.86Å; A302-A304 VanDerWaalsContact O-N 3.14Å; A302-V305 HydrophobicContact CB-CB 4.05Å; A302-V305 HydrophobicContact CB-CG2 3.99Å; A302-V305 WeakPolarHBondContact O-CB 3.36Å; A302-V305 PolarHBondContact O-N 3.15Å; A302-T306 PolarHBondContact O-N 3.38Å; A302-T306 VanDerWaalsContact O-N 3.08Å; A302-T306 PolarHBondContact O-OG1 3.29Å
303	V	86.3	Confident	87.3	Confident	3 Å²	3	48.6 Å²	48.6	2%	0.018	25%	0.254	C	S	.	.	H	α-helix	trans	-55.3	-39	-170.2	-177.8	0	0	0	0	112.5	Y288 I292 L297 S300 V305 F307	Y288-V303 HydrophobicContact CD1-CG1 4.04Å; Y288-V303 HydrophobicContact CD2-CG1 3.75Å; Y288-V303 HydrophobicContact CE1-CG1 4.09Å; Y288-V303 HydrophobicContact CE2-CG1 3.8Å; Y288-V303 HydrophobicContact CG-CG1 3.88Å; I292-V303 HydrophobicContact CD1-CG1 3.95Å; L297-V303 HydrophobicContact CD1-CG1 4.17Å; L297-V303 HydrophobicContact CD2-CG2 4.26Å; L297-V303 HydrophobicContact CG-CG1 3.95Å; L297-V303 HydrophobicContact CG-CG2 4.24Å; S300-V303 PolarHBondContact OG-N 3.18Å; V303-V305 VanDerWaalsContact C-N 3.31Å; V303-V305 PolarHBondContact O-N 2.84Å; V303-F307 WeakPolarHBondContact O-CB 3.29Å; V303-F307 PolarHBondContact O-N 3.16Å
304	A	87.7	Confident	86.9	Confident	0 Å²	0	52.7 Å²	52.7	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-64.8	-34.4	178.4	0	0	0	0	0	113.3	F63 I205 A302 S308 V319 V323	F63-A304 HydrophobicContact CD1-CB 3.83Å; F63-A304 HydrophobicContact CE1-CB 4.28Å; I205-A304 HydrophobicContact CD1-CB 4.14Å; A302-A304 PolarHBondContact O-N 2.86Å; A302-A304 VanDerWaalsContact O-N 3.14Å; A304-S308 WeakPolarHBondContact O-CB 3.48Å; A304-S308 PolarHBondContact O-N 3.47Å; A304-S308 VanDerWaalsContact O-N 3.1Å; A304-V319 HydrophobicContact CB-CG1 3.99Å; A304-V323 HydrophobicContact CB-CG2 4.21Å
305	V	86.8	Confident	86.7	Confident	8 Å²	8	56.4 Å²	56.4	5%	0.048	29%	0.287	C	S	.	.	H	α-helix	trans	-75.6	-46.7	179.7	178	0	0	0	0	109.6	Y149 E152 A302 V303 F307 S308 E309 P320	Y149-V305 HydrophobicContact CD1-CG2 4.16Å; Y149-V305 HydrophobicContact CE1-CG2 3.97Å; E152-V305 HydrophobicContact CG-CG1 4.16Å; E152-V305 HydrophobicContact CG-CG2 4.18Å; A302-V305 HydrophobicContact CB-CB 4.05Å; A302-V305 HydrophobicContact CB-CG2 3.99Å; A302-V305 WeakPolarHBondContact O-CB 3.36Å; A302-V305 PolarHBondContact O-N 3.15Å; V303-V305 VanDerWaalsContact C-N 3.31Å; V303-V305 PolarHBondContact O-N 2.84Å; V305-F307 VanDerWaalsContact C-N 3.27Å; V305-F307 PolarHBondContact O-N 3.38Å; V305-S308 PolarHBondContact O-N 3.01Å; V305-S308 PolarHBondContact O-OG 3.35Å; V305-E309 HydrophobicContact CG1-CG 4.35Å; V305-E309 WeakPolarHBondContact O-CG 2.97Å; V305-E309 PolarHBondContact O-N 2.86Å; V305-P320 HydrophobicContact CG2-CB 3.91Å; V305-P320 HydrophobicContact CG2-CG 4.28Å
306	T	88.3	Confident	86.5	Confident	25 Å²	25	50.3 Å²	50.3	15%	0.153	26%	0.26	C	S	.	.	H	α-helix	trans	-58.3	-41.3	175.3	-52.4	0	0	0	0	111.7	I292 E296 S300 A302 S308 R310	I292-T306 HydrophobicContact CG2-CG2 4.35Å; E296-T306 HydrophobicContact CG-CG2 4.07Å; S300-T306 WeakPolarHBondContact CB-OG1 3.5Å; S300-T306 PolarHBondContact OG-OG1 3.23Å; A302-T306 PolarHBondContact O-N 3.38Å; A302-T306 VanDerWaalsContact O-N 3.08Å; A302-T306 PolarHBondContact O-OG1 3.29Å; T306-S308 PolarHBondContact O-N 3.03Å; T306-R310 VanDerWaalsContact O-CG 3.29Å; T306-R310 WeakPolarHBondContact O-CG 3.13Å; T306-R310 PolarHBondContact O-N 2.9Å
307	F	90.3	Very high	86.3	Confident	0 Å²	0	52.4 Å²	52.4	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-60.1	-44.3	172.8	172.6	-89.4	0	0	0	112.4	I205 P208 A287 Y288 T291 V303 V305 R310 L311	I205-F307 HydrophobicContact CB-CE1 4.27Å; I205-F307 HydrophobicContact CG1-CD1 4.32Å; I205-F307 HydrophobicContact CG1-CE1 4.4Å; I205-F307 HydrophobicContact CG2-CD1 4.16Å; I205-F307 HydrophobicContact CG2-CE1 3.96Å; I205-F307 HydrophobicContact CG2-CZ 4.18Å; I205-F307 WeakPolarHBondContact O-CZ 3.26Å; P208-F307 HydrophobicContact CB-CZ 4.43Å; A287-F307 HydrophobicContact CB-CE2 4.32Å; A287-F307 HydrophobicContact CB-CZ 4.43Å; A287-F307 VanDerWaalsContact O-CE2 3.31Å; A287-F307 WeakPolarHBondContact O-CE2 3.25Å; Y288-F307 HydrophobicContact CD1-CB 3.84Å; Y288-F307 AromaticContact CD1-CD2 3.84Å; Y288-F307 HydrophobicContact CD1-CD2 3.84Å; Y288-F307 AromaticContact CD1-CG 3.88Å; Y288-F307 HydrophobicContact CD1-CG 3.88Å; Y288-F307 HydrophobicContact CE1-CB 3.97Å; Y288-F307 HydrophobicContact CE1-CG 4.14Å; T291-F307 HydrophobicContact CG2-CD2 4.07Å; T291-F307 HydrophobicContact CG2-CE2 4.16Å; T291-F307 WeakPolarHBondContact OG1-CE2 3.34Å; V303-F307 WeakPolarHBondContact O-CB 3.29Å; V303-F307 PolarHBondContact O-N 3.16Å; V305-F307 VanDerWaalsContact C-N 3.27Å; V305-F307 PolarHBondContact O-N 3.38Å; F307-R310 PolarHBondContact O-N 3.25Å; F307-L311 HydrophobicContact CE1-CD2 4.32Å; F307-L311 HydrophobicContact CE2-CD2 4.42Å; F307-L311 HydrophobicContact CZ-CD2 3.84Å
308	S	89	Confident	86.1	Confident	0 Å²	0	53.4 Å²	53.4	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-70.4	-37.8	-175.8	76.6	0	0	0	0	112.3	A304 V305 T306 R310 L311 L312 S316 V319	A304-S308 WeakPolarHBondContact O-CB 3.48Å; A304-S308 PolarHBondContact O-N 3.47Å; A304-S308 VanDerWaalsContact O-N 3.1Å; V305-S308 PolarHBondContact O-N 3.01Å; V305-S308 PolarHBondContact O-OG 3.35Å; T306-S308 PolarHBondContact O-N 3.03Å; S308-R310 VanDerWaalsContact C-N 3.3Å; S308-R310 PolarHBondContact O-N 3.44Å; S308-L311 PolarHBondContact O-N 3.44Å; S308-L312 WeakPolarHBondContact O-CA 3.31Å; S308-L312 WeakPolarHBondContact O-CB 3.46Å; S308-L312 PolarHBondContact O-N 3.09Å; S308-S316 WeakPolarHBondContact OG-CA 3.45Å; S308-S316 WeakPolarHBondContact OG-CB 3.39Å; S308-S316 PolarHBondContact OG-O 3.5Å; S308-V319 VanDerWaalsContact CB-CG2 3.46Å
309	E	88.4	Confident	86.1	Confident	92 Å²	92	50.7 Å²	50.7	43%	0.43	27%	0.266	S	S	.	.	H	α-helix	trans	-61.9	-37.2	175.6	-72.2	175.4	162.5	0	0	112.3	V305 L311	V305-E309 HydrophobicContact CG1-CG 4.35Å; V305-E309 WeakPolarHBondContact O-CG 2.97Å; V305-E309 PolarHBondContact O-N 2.86Å; E309-L311 VanDerWaalsContact C-N 3.31Å; E309-L311 PolarHBondContact O-N 3.13Å
310	R	87.8	Confident	86.2	Confident	160 Å²	160	44 Å²	44	60%	0.604	23%	0.231	S	C	*	.	H	α-helix	trans	-68.9	-26.4	179	-71	-68.8	-169.3	168.8	0.6	114	T291 I292 E296 T306 F307 S308	T291-R310 HydrophobicContact CG2-CB 3.71Å; I292-R310 HydrophobicContact CG2-CG 3.95Å; E296-R310 VanDerWaalsContact CD-NH2 3.31Å; E296-R310 IonicContact OE1-CZ 3.39Å; E296-R310 IonicContact OE1-NE 3.72Å; E296-R310 PolarHBondContact OE1-NE 3.01Å; E296-R310 IonicContact OE1-NH2 3.85Å; E296-R310 PolarHBondContact OE1-NH2 3.27Å; E296-R310 IonicContact OE2-CZ 2.81Å; E296-R310 IonicContact OE2-NE 2.7Å; E296-R310 IonicContact OE2-NH2 3.17Å; E296-R310 PolarHBondContact OE2-NH2 2.99Å; T306-R310 VanDerWaalsContact O-CG 3.29Å; T306-R310 WeakPolarHBondContact O-CG 3.13Å; T306-R310 PolarHBondContact O-N 2.9Å; F307-R310 PolarHBondContact O-N 3.25Å; S308-R310 VanDerWaalsContact C-N 3.3Å; S308-R310 PolarHBondContact O-N 3.44Å
311	L	88.6	Confident	86.5	Confident	52 Å²	52	47.2 Å²	47.2	27%	0.272	25%	0.247	S	C	.	.	H	α-helix	trans	-126	-31.7	-165.1	-164.6	65.5	0	0	0	115	P208 Q212 T291 F307 S308 E309	P208-L311 HydrophobicContact CB-CD2 3.25Å; P208-L311 HydrophobicContact CB-CG 4.26Å; Q212-L311 HydrophobicContact CG-CD1 3.87Å; Q212-L311 HydrophobicContact CG-CD2 4.05Å; T291-L311 HydrophobicContact CG2-CB 4.23Å; F307-L311 HydrophobicContact CE1-CD2 4.32Å; F307-L311 HydrophobicContact CE2-CD2 4.42Å; F307-L311 HydrophobicContact CZ-CD2 3.84Å; S308-L311 PolarHBondContact O-N 3.44Å; E309-L311 VanDerWaalsContact C-N 3.31Å; E309-L311 PolarHBondContact O-N 3.13Å
312	L	85.9	Confident	87.2	Confident	37 Å²	37	45 Å²	45	19%	0.194	23%	0.233	C	C	.	.	S	Bend	trans	-104.1	-2.5	-166.7	-56.8	-179.2	0	0	0	113.8	I204 P208 S308 N314 F315 V319	I204-L312 HydrophobicContact CG2-CD1 3.74Å; P208-L312 HydrophobicContact CB-CD2 4.29Å; P208-L312 HydrophobicContact CG-CD2 3.97Å; S308-L312 WeakPolarHBondContact O-CA 3.31Å; S308-L312 WeakPolarHBondContact O-CB 3.46Å; S308-L312 PolarHBondContact O-N 3.09Å; L312-N314 PolarHBondContact O-N 3.26Å; L312-F315 HydrophobicContact CB-CB 4.23Å; L312-F315 HydrophobicContact CB-CD1 4.42Å; L312-F315 HydrophobicContact CD1-CD1 4.07Å; L312-F315 WeakPolarHBondContact O-CB 3.41Å; L312-F315 PolarHBondContact O-N 2.93Å; L312-V319 HydrophobicContact CD1-CG2 4.01Å
313	G	84.8	Confident	87.6	Confident	43 Å²	43	44.9 Å²	44.9	44%	0.443	23%	0.232	S	C	.	.	G	3₁₀ helix	trans	53	-127.1	-179.5	0	0	0	0	0	111	F315 S316	G313-F315 PolarHBondContact O-N 3.34Å; G313-F315 VanDerWaalsContact O-N 3.14Å; G313-S316 WeakPolarHBondContact O-CB 3.49Å; G313-S316 PolarHBondContact O-N 3.16Å; G313-S316 PolarHBondContact O-OG 3.08Å
314	N	82.5	Confident	87.9	Confident	158 Å²	158	44.7 Å²	44.7	85%	0.845	23%	0.231	S	C	*	.	G	3₁₀ helix	trans	-61.7	-22.8	-179.7	-65.8	-5.1	0	0	0	114.4	L312 S316	L312-N314 PolarHBondContact O-N 3.26Å; N314-S316 PolarHBondContact O-N 3.3Å
315	F	83.6	Confident	88.1	Confident	108 Å²	108	47.2 Å²	47.2	47%	0.474	24%	0.244	S	C	.	.	G	3₁₀ helix	trans	-76.8	-5.7	176.7	-169	-105.5	0	0	0	112.4	I204 L312 G313 L317 A318	I204-F315 HydrophobicContact CD1-CE1 4.01Å; I204-F315 HydrophobicContact CD1-CZ 4.08Å; I204-F315 HydrophobicContact CG1-CE1 4.24Å; I204-F315 HydrophobicContact CG2-CE1 3.92Å; L312-F315 HydrophobicContact CB-CB 4.23Å; L312-F315 HydrophobicContact CB-CD1 4.42Å; L312-F315 HydrophobicContact CD1-CD1 4.07Å; L312-F315 WeakPolarHBondContact O-CB 3.41Å; L312-F315 PolarHBondContact O-N 2.93Å; G313-F315 PolarHBondContact O-N 3.34Å; G313-F315 VanDerWaalsContact O-N 3.14Å; F315-L317 PolarHBondContact O-N 3.04Å; F315-A318 HydrophobicContact CD1-CB 4.47Å; F315-A318 HydrophobicContact CD2-CB 3.99Å; F315-A318 HydrophobicContact CE1-CB 4.22Å; F315-A318 HydrophobicContact CE2-CB 3.7Å; F315-A318 HydrophobicContact CG-CB 4.37Å; F315-A318 HydrophobicContact CZ-CB 3.82Å; F315-A318 WeakPolarHBondContact O-CB 3.24Å; F315-A318 PolarHBondContact O-N 3.29Å; F315-A318 VanDerWaalsContact O-N 3.07Å
316	S	83.3	Confident	88.4	Confident	17 Å²	17	46.9 Å²	46.9	12%	0.119	24%	0.242	C	C	.	.	G	3₁₀ helix	trans	-55.6	-32.8	174.8	67.2	0	0	0	0	112.7	S308 G313 N314 A318 V319 P320	S308-S316 WeakPolarHBondContact OG-CA 3.45Å; S308-S316 WeakPolarHBondContact OG-CB 3.39Å; S308-S316 PolarHBondContact OG-O 3.5Å; G313-S316 WeakPolarHBondContact O-CB 3.49Å; G313-S316 PolarHBondContact O-N 3.16Å; G313-S316 PolarHBondContact O-OG 3.08Å; N314-S316 PolarHBondContact O-N 3.3Å; S316-A318 VanDerWaalsContact C-N 3.25Å; S316-A318 PolarHBondContact O-N 3.4Å; S316-V319 PolarHBondContact O-N 2.94Å; S316-P320 WeakPolarHBondContact O-CD 3.29Å
317	L	85.4	Confident	88.6	Confident	81 Å²	81	45.7 Å²	45.7	42%	0.424	23%	0.234	S	C	.	.	G	3₁₀ helix	trans	-65.5	-22.8	179	-60	179	0	0	0	113.8	P153 I156 F315 P320	P153-L317 HydrophobicContact CB-CD2 4.35Å; I156-L317 HydrophobicContact CD1-CD2 3.65Å; F315-L317 PolarHBondContact O-N 3.04Å; L317-P320 WeakPolarHBondContact O-CD 3.33Å; L317-P320 WeakPolarHBondContact O-CG 3.37Å
318	A	86.8	Confident	88.7	Confident	20 Å²	20	47 Å²	47	17%	0.165	24%	0.24	C	C	.	.	H	α-helix	trans	-74.2	-31.9	178.7	0	0	0	0	0	112.1	F315 S316 I321 F322	F315-A318 HydrophobicContact CD1-CB 4.47Å; F315-A318 HydrophobicContact CD2-CB 3.99Å; F315-A318 HydrophobicContact CE1-CB 4.22Å; F315-A318 HydrophobicContact CE2-CB 3.7Å; F315-A318 HydrophobicContact CG-CB 4.37Å; F315-A318 HydrophobicContact CZ-CB 3.82Å; F315-A318 WeakPolarHBondContact O-CB 3.24Å; F315-A318 PolarHBondContact O-N 3.29Å; F315-A318 VanDerWaalsContact O-N 3.07Å; S316-A318 VanDerWaalsContact C-N 3.25Å; S316-A318 PolarHBondContact O-N 3.4Å; A318-I321 PolarHBondContact O-N 3.48Å; A318-F322 HydrophobicContact CB-CD2 4.28Å; A318-F322 HydrophobicContact CB-CE2 4.15Å; A318-F322 WeakPolarHBondContact O-CD2 3.16Å; A318-F322 PolarHBondContact O-N 3.41Å
319	V	89.4	Confident	88.8	Confident	4 Å²	4	47 Å²	47	2%	0.024	24%	0.24	C	C	.	.	H	α-helix	trans	-60.3	-54.3	-177.2	178.2	0	0	0	0	113.1	I204 A304 S308 L312 S316 I321 F322 V323	I204-V319 HydrophobicContact CG2-CG2 3.8Å; A304-V319 HydrophobicContact CB-CG1 3.99Å; S308-V319 VanDerWaalsContact CB-CG2 3.46Å; L312-V319 HydrophobicContact CD1-CG2 4.01Å; S316-V319 PolarHBondContact O-N 2.94Å; V319-I321 PolarHBondContact O-N 3.22Å; V319-F322 PolarHBondContact O-N 3.25Å; V319-F322 VanDerWaalsContact O-N 3.13Å; V319-V323 HydrophobicContact CG1-CG2 4.24Å; V319-V323 VanDerWaalsContact O-CG2 3.3Å; V319-V323 WeakPolarHBondContact O-CG2 3.44Å; V319-V323 PolarHBondContact O-N 3.2Å
320	P	89.8	Confident	88.9	Confident	3 Å²	3	42.8 Å²	42.8	2%	0.019	22%	0.221	C	C	.	.	H	α-helix	trans	-58	-35	177.9	20.3	-31.5	0	0	0	112.8	Y149 E152 P153 V305 S316 L317 V323 A324	Y149-P320 HydrophobicContact CD1-CB 4.36Å; Y149-P320 WeakPolarHBondContact O-CB 3.3Å; E152-P320 HydrophobicContact CB-CB 4.17Å; P153-P320 HydrophobicContact CG-CB 4.08Å; P153-P320 HydrophobicContact CG-CG 3.65Å; V305-P320 HydrophobicContact CG2-CB 3.91Å; V305-P320 HydrophobicContact CG2-CG 4.28Å; S316-P320 WeakPolarHBondContact O-CD 3.29Å; L317-P320 WeakPolarHBondContact O-CD 3.33Å; L317-P320 WeakPolarHBondContact O-CG 3.37Å; P320-V323 PolarHBondContact O-N 3.46Å; P320-A324 WeakPolarHBondContact O-CB 3.41Å; P320-A324 PolarHBondContact O-N 3.09Å
321	I	91.1	Very high	89	Confident	79 Å²	79	35.3 Å²	35.3	41%	0.405	19%	0.193	S	C	.	.	H	α-helix	trans	-65.1	-47.4	175.9	-60.6	171.9	0	0	0	110.8	A318 V319 V323 A324 L325	A318-I321 PolarHBondContact O-N 3.48Å; V319-I321 PolarHBondContact O-N 3.22Å; I321-V323 VanDerWaalsContact C-N 3.31Å; I321-V323 PolarHBondContact O-N 3.37Å; I321-A324 PolarHBondContact O-N 3.1Å; I321-L325 HydrophobicContact CG2-CD1 4.4Å; I321-L325 WeakPolarHBondContact O-CG 3.29Å; I321-L325 PolarHBondContact O-N 3.38Å
322	F	91.9	Very high	89	Confident	52 Å²	52	32.9 Å²	32.9	23%	0.228	18%	0.18	C	C	.	.	H	α-helix	trans	-64.6	-35.9	176.8	-77.9	-59.5	0	0	0	112.6	C197 T200 A201 I204 A318 V319 L325 S326	C197-F322 HydrophobicContact CB-CD1 4.32Å; T200-F322 HydrophobicContact CG2-CZ 4.42Å; A201-F322 HydrophobicContact CB-CB 3.7Å; I204-F322 HydrophobicContact CD1-CD2 3.65Å; I204-F322 HydrophobicContact CD1-CE2 3.6Å; I204-F322 HydrophobicContact CD1-CZ 4.48Å; A318-F322 HydrophobicContact CB-CD2 4.28Å; A318-F322 HydrophobicContact CB-CE2 4.15Å; A318-F322 WeakPolarHBondContact O-CD2 3.16Å; A318-F322 PolarHBondContact O-N 3.41Å; V319-F322 PolarHBondContact O-N 3.25Å; V319-F322 VanDerWaalsContact O-N 3.13Å; F322-L325 HydrophobicContact CD1-CD1 4.39Å; F322-L325 PolarHBondContact O-N 3.21Å; F322-S326 WeakPolarHBondContact O-CB 3.18Å; F322-S326 PolarHBondContact O-N 3.09Å
323	V	90.9	Very high	89	Confident	0 Å²	0	31.4 Å²	31.4	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-66.3	-41.1	173.6	176.1	0	0	0	0	111.3	F63 Y149 A304 V319 P320 I321 S326 C327	F63-V323 HydrophobicContact CB-CG1 4.27Å; F63-V323 HydrophobicContact CD1-CG1 4.29Å; F63-V323 HydrophobicContact CD1-CG2 3.93Å; F63-V323 HydrophobicContact CD2-CB 4.44Å; F63-V323 HydrophobicContact CD2-CG1 3.47Å; F63-V323 VanDerWaalsContact CD2-CG1 3.47Å; F63-V323 HydrophobicContact CD2-CG2 4.3Å; F63-V323 HydrophobicContact CE1-CG2 3.66Å; F63-V323 HydrophobicContact CE2-CB 4.32Å; F63-V323 HydrophobicContact CE2-CG1 3.78Å; F63-V323 HydrophobicContact CE2-CG2 4.05Å; F63-V323 HydrophobicContact CG-CG1 3.75Å; F63-V323 HydrophobicContact CG-CG2 4.24Å; F63-V323 HydrophobicContact CZ-CB 4.46Å; F63-V323 HydrophobicContact CZ-CG1 4.32Å; F63-V323 HydrophobicContact CZ-CG2 3.73Å; Y149-V323 HydrophobicContact CD1-CB 3.86Å; Y149-V323 HydrophobicContact CD1-CG1 3.55Å; Y149-V323 HydrophobicContact CD1-CG2 4.48Å; Y149-V323 HydrophobicContact CD2-CG1 3.49Å; Y149-V323 VanDerWaalsContact CD2-CG1 3.49Å; Y149-V323 HydrophobicContact CE1-CB 4.25Å; Y149-V323 HydrophobicContact CE1-CG1 3.73Å; Y149-V323 HydrophobicContact CE1-CG2 4.48Å; Y149-V323 HydrophobicContact CE2-CG1 3.72Å; Y149-V323 HydrophobicContact CG-CB 4.04Å; Y149-V323 HydrophobicContact CG-CG1 3.44Å; Y149-V323 VanDerWaalsContact CG-CG1 3.44Å; A304-V323 HydrophobicContact CB-CG2 4.21Å; V319-V323 HydrophobicContact CG1-CG2 4.24Å; V319-V323 VanDerWaalsContact O-CG2 3.3Å; V319-V323 WeakPolarHBondContact O-CG2 3.44Å; V319-V323 PolarHBondContact O-N 3.2Å; P320-V323 PolarHBondContact O-N 3.46Å; I321-V323 VanDerWaalsContact C-N 3.31Å; I321-V323 PolarHBondContact O-N 3.37Å; V323-S326 WeakPolarHBondContact O-CA 3.4Å; V323-S326 VanDerWaalsContact O-CB 3.24Å; V323-S326 WeakPolarHBondContact O-CB 3.47Å; V323-S326 PolarHBondContact O-N 2.97Å; V323-C327 PolarHBondContact O-N 3.1Å; V323-C327 PolarHBondContact O-SG 3.02Å; V323-C327 VanDerWaalsContact O-SG 3.32Å
324	A	92.8	Very high	89	Confident	0 Å²	0	29.7 Å²	29.7	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-62.1	-47.2	174.1	0	0	0	0	0	111	F146 I150 P320 I321 S326 C327 F328	F146-A324 HydrophobicContact CD2-CB 3.97Å; F146-A324 WeakPolarHBondContact CD2-O 3.29Å; F146-A324 HydrophobicContact CE2-CB 4.24Å; I150-A324 HydrophobicContact CB-CB 3.95Å; I150-A324 HydrophobicContact CD1-CB 3.9Å; P320-A324 WeakPolarHBondContact O-CB 3.41Å; P320-A324 PolarHBondContact O-N 3.09Å; I321-A324 PolarHBondContact O-N 3.1Å; A324-S326 PolarHBondContact O-N 3.09Å; A324-C327 PolarHBondContact O-N 2.78Å; A324-C327 VanDerWaalsContact O-N 3.09Å; A324-F328 PolarHBondContact O-N 2.71Å
325	L	93.4	Very high	89.2	Confident	53 Å²	53	22.2 Å²	22.2	28%	0.277	12%	0.117	S	C	.	.	H	α-helix	trans	-58.7	-35.3	173.7	-68.9	175.3	0	0	0	112.1	L194 C197 I321 F322 F328 G329	L194-L325 HydrophobicContact CD2-CB 4.21Å; L194-L325 HydrophobicContact CD2-CD2 4.09Å; C197-L325 HydrophobicContact CB-CB 4.42Å; C197-L325 HydrophobicContact CB-CD1 4.45Å; I321-L325 HydrophobicContact CG2-CD1 4.4Å; I321-L325 WeakPolarHBondContact O-CG 3.29Å; I321-L325 PolarHBondContact O-N 3.38Å; F322-L325 HydrophobicContact CD1-CD1 4.39Å; F322-L325 PolarHBondContact O-N 3.21Å; L325-F328 PolarHBondContact O-N 3.38Å; L325-G329 PolarHBondContact O-N 3.1Å
326	S	92.7	Very high	89.1	Confident	0 Å²	0	18 Å²	18	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-60.4	-51	172.3	176.2	0	0	0	0	111.8	K198 F322 V323 A324 F328 G329 S330	K198-S326 WeakPolarHBondContact CE-O 3.37Å; K198-S326 WeakPolarHBondContact CG-OG 3.5Å; K198-S326 PolarHBondContact NZ-O 3.31Å; F322-S326 WeakPolarHBondContact O-CB 3.18Å; F322-S326 PolarHBondContact O-N 3.09Å; V323-S326 WeakPolarHBondContact O-CA 3.4Å; V323-S326 VanDerWaalsContact O-CB 3.24Å; V323-S326 WeakPolarHBondContact O-CB 3.47Å; V323-S326 PolarHBondContact O-N 2.97Å; A324-S326 PolarHBondContact O-N 3.09Å; S326-F328 VanDerWaalsContact C-N 3.3Å; S326-F328 PolarHBondContact O-N 2.94Å; S326-G329 PolarHBondContact O-N 2.83Å; S326-S330 PolarHBondContact O-N 3.28Å; S326-S330 VanDerWaalsContact O-N 3.08Å; S326-S330 PolarHBondContact O-OG 3.49Å; S326-S330 VanDerWaalsContact O-OG 3.14Å
327	C	92.3	Very high	88.8	Confident	0 Å²	0	17.3 Å²	17.3	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-61.3	-40.5	177.5	-62.5	0	0	0	0	111.5	I142 F146 V323 A324 G329 S330 M331	I142-C327 HydrophobicContact CG2-CB 4.35Å; I142-C327 WeakPolarHBondContact CG2-O 3.26Å; F146-C327 HydrophobicContact CB-CB 3.64Å; V323-C327 PolarHBondContact O-N 3.1Å; V323-C327 PolarHBondContact O-SG 3.02Å; V323-C327 VanDerWaalsContact O-SG 3.32Å; A324-C327 PolarHBondContact O-N 2.78Å; A324-C327 VanDerWaalsContact O-N 3.09Å; C327-G329 PolarHBondContact O-N 3.32Å; C327-S330 WeakPolarHBondContact O-CB 3.08Å; C327-S330 PolarHBondContact O-N 2.8Å; C327-S330 VanDerWaalsContact O-N 3.11Å; C327-M331 WeakPolarHBondContact O-CG 3.46Å; C327-M331 PolarHBondContact O-N 3.47Å
328	F	92.6	Very high	88.6	Confident	27 Å²	27	13.5 Å²	13.5	12%	0.118	7%	0.074	C	C	.	.	H	α-helix	trans	-58.9	-44.9	175.2	-169.4	-83.1	0	0	0	112.8	F146 V175 V176 L179 L194 A324 L325 S326 S330 M331 N332	F146-F328 HydrophobicContact CD2-CB 4.17Å; F146-F328 HydrophobicContact CE2-CB 4.33Å; F146-F328 HydrophobicContact CE2-CD2 4.15Å; F146-F328 HydrophobicContact CZ-CD2 4.44Å; V175-F328 HydrophobicContact CG1-CE2 4.25Å; V175-F328 HydrophobicContact CG1-CZ 4.09Å; V176-F328 HydrophobicContact CG2-CD1 4.3Å; V176-F328 HydrophobicContact CG2-CD2 3.77Å; V176-F328 HydrophobicContact CG2-CE1 3.98Å; V176-F328 HydrophobicContact CG2-CE2 3.39Å; V176-F328 HydrophobicContact CG2-CG 4.22Å; V176-F328 HydrophobicContact CG2-CZ 3.51Å; L179-F328 HydrophobicContact CD1-CE1 4.25Å; L179-F328 HydrophobicContact CD1-CZ 3.89Å; L194-F328 HydrophobicContact CD1-CD1 3.62Å; L194-F328 HydrophobicContact CD1-CE1 4.13Å; L194-F328 HydrophobicContact CD2-CD1 4.36Å; A324-F328 PolarHBondContact O-N 2.71Å; L325-F328 PolarHBondContact O-N 3.38Å; S326-F328 VanDerWaalsContact C-N 3.3Å; S326-F328 PolarHBondContact O-N 2.94Å; F328-S330 VanDerWaalsContact C-N 3.29Å; F328-S330 PolarHBondContact O-N 3.1Å; F328-M331 HydrophobicContact CB-CE 4.21Å; F328-M331 HydrophobicContact CD2-CE 4.06Å; F328-M331 HydrophobicContact CG-CE 4.4Å; F328-M331 PolarHBondContact O-N 2.97Å; F328-N332 PolarHBondContact O-N 2.92Å
329	G	90.7	Very high	88.4	Confident	0 Å²	0	12.8 Å²	12.8	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-65.4	-30.3	175	0	0	0	0	0	113.8	Q191 L325 S326 C327 G333	Q191-G329 PolarHBondContact NE2-O 3.05Å; Q191-G329 PolarHBondContact OE1-O 3.04Å; L325-G329 PolarHBondContact O-N 3.1Å; S326-G329 PolarHBondContact O-N 2.83Å; C327-G329 PolarHBondContact O-N 3.32Å; G329-G333 PolarHBondContact O-N 3.38Å
330	S	90	Very high	87.9	Confident	5 Å²	5	13.1 Å²	13.1	4%	0.035	7%	0.068	C	C	.	.	H	α-helix	trans	-71.4	-40.9	176.2	-56.8	0	0	0	0	111.4	I58 G59 K198 S326 C327 F328 N332 G334	I58-S330 PolarHBondContact O-OG 3.06Å; G59-S330 WeakPolarHBondContact CA-OG 3.2Å; K198-S330 VanDerWaalsContact NZ-N 3.16Å; K198-S330 PolarHBondContact NZ-OG 3.04Å; S326-S330 PolarHBondContact O-N 3.28Å; S326-S330 VanDerWaalsContact O-N 3.08Å; S326-S330 PolarHBondContact O-OG 3.49Å; S326-S330 VanDerWaalsContact O-OG 3.14Å; C327-S330 WeakPolarHBondContact O-CB 3.08Å; C327-S330 PolarHBondContact O-N 2.8Å; C327-S330 VanDerWaalsContact O-N 3.11Å; F328-S330 VanDerWaalsContact C-N 3.29Å; F328-S330 PolarHBondContact O-N 3.1Å; S330-N332 VanDerWaalsContact C-N 3.35Å; S330-G334 PolarHBondContact O-N 2.91Å
331	M	90.6	Very high	87.7	Confident	2 Å²	2	13 Å²	13	1%	0.01	7%	0.067	C	C	.	.	H	α-helix	trans	-59.5	-47.7	172.5	-65.4	-172.1	-79.4	0	0	110.6	I142 S143 F146 V176 C327 F328 G334 V335	I142-M331 HydrophobicContact CB-CG 4.34Å; I142-M331 HydrophobicContact CG2-CG 3.65Å; S143-M331 VanDerWaalsContact CA-SD 3.51Å; S143-M331 WeakPolarHBondContact CB-SD 3.36Å; F146-M331 HydrophobicContact CB-CE 3.82Å; F146-M331 HydrophobicContact CD1-CE 4.05Å; F146-M331 HydrophobicContact CD2-CE 4.28Å; F146-M331 HydrophobicContact CG-CE 3.77Å; V176-M331 HydrophobicContact CG1-CB 4.08Å; V176-M331 HydrophobicContact CG2-CB 4.11Å; V176-M331 HydrophobicContact CG2-CE 4.2Å; C327-M331 WeakPolarHBondContact O-CG 3.46Å; C327-M331 PolarHBondContact O-N 3.47Å; F328-M331 HydrophobicContact CB-CE 4.21Å; F328-M331 HydrophobicContact CD2-CE 4.06Å; F328-M331 HydrophobicContact CG-CE 4.4Å; F328-M331 PolarHBondContact O-N 2.97Å; M331-G334 PolarHBondContact O-N 3.05Å; M331-V335 WeakPolarHBondContact O-CG2 3.45Å; M331-V335 PolarHBondContact O-N 3.25Å
332	N	89	Confident	87.5	Confident	1 Å²	1	9.2 Å²	9.2	1%	0.005	5%	0.048	C	C	.	.	H	α-helix	trans	-60.5	-49.1	-179.5	-173.8	66.3	0	0	0	112.4	V176 N180 S187 Q191 F328 S330 G334 F336	V176-N332 HydrophobicContact CG1-CB 4.18Å; N180-N332 PolarHBondContact ND2-OD1 2.85Å; S187-N332 PolarHBondContact O-ND2 3.43Å; S187-N332 PolarHBondContact OG-ND2 3.39Å; S187-N332 PolarHBondContact OG-OD1 3.4Å; S187-N332 VanDerWaalsContact OG-OD1 3.08Å; Q191-N332 PolarHBondContact OE1-ND2 2.82Å; F328-N332 PolarHBondContact O-N 2.92Å; S330-N332 VanDerWaalsContact C-N 3.35Å; N332-G334 VanDerWaalsContact C-N 3.33Å; N332-G334 PolarHBondContact O-N 3.37Å; N332-F336 WeakPolarHBondContact O-CB 3.37Å; N332-F336 PolarHBondContact O-N 3.23Å
333	G	84.6	Confident	87.1	Confident	6 Å²	6	7 Å²	7	6%	0.062	4%	0.038	C	C	.	.	H	α-helix	trans	-62.7	-37.1	175.5	0	0	0	0	0	113.5	G329 F336 A337	G329-G333 PolarHBondContact O-N 3.38Å; G333-F336 WeakPolarHBondContact O-CB 3.37Å; G333-F336 PolarHBondContact O-N 3.21Å; G333-A337 PolarHBondContact O-N 2.9Å; G333-A337 VanDerWaalsContact O-N 3.12Å
334	G	85.8	Confident	86.7	Confident	8 Å²	8	7.2 Å²	7.2	8%	0.082	4%	0.04	C	C	.	.	H	α-helix	trans	-63.4	-51.8	176.5	0	0	0	0	0	112.6	S330 M331 N332 F336 A337 V338	S330-G334 PolarHBondContact O-N 2.91Å; M331-G334 PolarHBondContact O-N 3.05Å; N332-G334 VanDerWaalsContact C-N 3.33Å; N332-G334 PolarHBondContact O-N 3.37Å; G334-F336 VanDerWaalsContact C-N 3.28Å; G334-F336 PolarHBondContact O-N 2.71Å; G334-A337 PolarHBondContact O-N 2.74Å; G334-V338 VanDerWaalsContact O-CG2 3.25Å; G334-V338 WeakPolarHBondContact O-CG2 3.17Å; G334-V338 PolarHBondContact O-N 3.49Å
335	V	86.3	Confident	86.5	Confident	1 Å²	1	7.2 Å²	7.2	1%	0.006	4%	0.04	C	C	.	.	H	α-helix	trans	-61	-40.5	177.3	174.4	0	0	0	0	110.8	V176 M177 N180 M331 A337 V338 S339 V369 L372	V176-V335 HydrophobicContact CG1-CG2 4.22Å; M177-V335 HydrophobicContact CE-CG2 3.65Å; M177-V335 HydrophobicContact SD-CB 4.5Å; M177-V335 HydrophobicContact SD-CG1 3.83Å; M177-V335 HydrophobicContact SD-CG2 3.76Å; N180-V335 HydrophobicContact CB-CG1 3.86Å; M331-V335 WeakPolarHBondContact O-CG2 3.45Å; M331-V335 PolarHBondContact O-N 3.25Å; V335-A337 PolarHBondContact O-N 2.98Å; V335-V338 PolarHBondContact O-N 2.87Å; V335-S339 PolarHBondContact O-N 3.43Å; V335-S339 VanDerWaalsContact O-N 3.12Å; V335-S339 PolarHBondContact O-OG 2.77Å; V335-V369 HydrophobicContact CG1-CG1 4.03Å; V335-V369 HydrophobicContact CG1-CG2 4.27Å; V335-L372 HydrophobicContact CG2-CD2 4.42Å
336	F	81.3	Confident	86.2	Confident	18 Å²	18	5 Å²	5	8%	0.079	3%	0.028	C	C	.	.	H	α-helix	trans	-55.6	-49.5	176	-175.1	-96.4	0	0	0	112.1	V184 V255 N332 G333 G334 S339 R340	V184-F336 HydrophobicContact CG1-CE2 3.9Å; V184-F336 HydrophobicContact CG1-CZ 4.41Å; V255-F336 HydrophobicContact CG1-CE1 4.05Å; N332-F336 WeakPolarHBondContact O-CB 3.37Å; N332-F336 PolarHBondContact O-N 3.23Å; G333-F336 WeakPolarHBondContact O-CB 3.37Å; G333-F336 PolarHBondContact O-N 3.21Å; G334-F336 VanDerWaalsContact C-N 3.28Å; G334-F336 PolarHBondContact O-N 2.71Å; F336-S339 PolarHBondContact O-OG 3.39Å; F336-R340 VanDerWaalsContact CZ-CZ 3.41Å; F336-R340 WeakPolarHBondContact O-CD 3.29Å; F336-R340 PolarHBondContact O-NH1 2.96Å
337	A	78.3	Confident	85.8	Confident	4 Å²	4	8.9 Å²	8.9	3%	0.033	4%	0.043	C	C	.	.	H	α-helix	trans	-71.8	-39.3	-179	0	0	0	0	0	113.5	Y251 F254 G333 G334 V335 S339 R340 L341	Y251-A337 HydrophobicContact CD1-CB 3.33Å; Y251-A337 HydrophobicContact CE1-CB 3.82Å; Y251-A337 HydrophobicContact CG-CB 4.32Å; F254-A337 HydrophobicContact CB-CB 4.4Å; G333-A337 PolarHBondContact O-N 2.9Å; G333-A337 VanDerWaalsContact O-N 3.12Å; G334-A337 PolarHBondContact O-N 2.74Å; V335-A337 PolarHBondContact O-N 2.98Å; A337-S339 VanDerWaalsContact C-N 3.34Å; A337-S339 PolarHBondContact O-N 3.4Å; A337-R340 PolarHBondContact O-N 3.26Å; A337-L341 PolarHBondContact O-N 3.08Å
338	V	81	Confident	85.6	Confident	1 Å²	1	12.5 Å²	12.5	1%	0.006	6%	0.06	C	C	.	.	H	α-helix	trans	-64.8	-39.1	-177.7	172.2	0	0	0	0	111.9	R135 G334 V335 R340 L341 F342 L372	R135-V338 HydrophobicContact CB-CG1 4.38Å; R135-V338 HydrophobicContact CB-CG2 4.15Å; R135-V338 HydrophobicContact CG-CG1 4.12Å; R135-V338 HydrophobicContact CG-CG2 3.58Å; G334-V338 VanDerWaalsContact O-CG2 3.25Å; G334-V338 WeakPolarHBondContact O-CG2 3.17Å; G334-V338 PolarHBondContact O-N 3.49Å; V335-V338 PolarHBondContact O-N 2.87Å; V338-R340 PolarHBondContact O-N 3.05Å; V338-L341 WeakPolarHBondContact O-CB 3.29Å; V338-L341 PolarHBondContact O-N 3.39Å; V338-F342 HydrophobicContact CG1-CD2 3.87Å; V338-F342 HydrophobicContact CG1-CE1 4.08Å; V338-F342 HydrophobicContact CG1-CE2 3.31Å; V338-F342 HydrophobicContact CG1-CG 4.45Å; V338-F342 HydrophobicContact CG1-CZ 3.4Å; V338-F342 VanDerWaalsContact CG1-CZ 3.4Å; V338-F342 PolarHBondContact O-N 2.74Å; V338-L372 HydrophobicContact CB-CD2 4.36Å; V338-L372 HydrophobicContact CG1-CD2 3.94Å
339	S	82.3	Confident	85.3	Confident	4 Å²	4	13.4 Å²	13.4	3%	0.028	8%	0.077	C	C	.	.	H	α-helix	trans	-56.9	-36.4	176.7	62	0	0	0	0	112.7	V335 F336 A337 Y343	V335-S339 PolarHBondContact O-N 3.43Å; V335-S339 VanDerWaalsContact O-N 3.12Å; V335-S339 PolarHBondContact O-OG 2.77Å; F336-S339 PolarHBondContact O-OG 3.39Å; A337-S339 VanDerWaalsContact C-N 3.34Å; A337-S339 PolarHBondContact O-N 3.4Å; S339-Y343 VanDerWaalsContact O-CB 3.26Å; S339-Y343 WeakPolarHBondContact O-CB 3.42Å; S339-Y343 PolarHBondContact O-N 3.14Å
340	R	79.7	Confident	85.3	Confident	11 Å²	11	14 Å²	14	4%	0.042	8%	0.08	C	C	.	.	H	α-helix	trans	-72.1	-36	175.2	-78	85.7	178.8	135.7	5	112.7	V255 E258 F336 A337 V338 Y343 V344	V255-R340 HydrophobicContact CG1-CB 4.43Å; V255-R340 HydrophobicContact CG1-CG 4.01Å; E258-R340 IonicContact OE1-CZ 2.73Å; E258-R340 IonicContact OE1-NE 3.71Å; E258-R340 PolarHBondContact OE1-NE 3.43Å; E258-R340 IonicContact OE1-NH2 2.69Å; E258-R340 IonicContact OE2-NH2 3.17Å; F336-R340 VanDerWaalsContact CZ-CZ 3.41Å; F336-R340 WeakPolarHBondContact O-CD 3.29Å; F336-R340 PolarHBondContact O-NH1 2.96Å; A337-R340 PolarHBondContact O-N 3.26Å; V338-R340 PolarHBondContact O-N 3.05Å; R340-Y343 WeakPolarHBondContact O-CB 3.3Å; R340-Y343 PolarHBondContact O-N 3.38Å; R340-V344 WeakPolarHBondContact O-CB 3.39Å; R340-V344 VanDerWaalsContact O-CG2 3.29Å; R340-V344 WeakPolarHBondContact O-CG2 3.15Å; R340-V344 PolarHBondContact O-N 3.24Å
341	L	84.9	Confident	85.2	Confident	0 Å²	0	14.7 Å²	14.7	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-62.6	-46.8	176.4	175.7	56.8	0	0	0	111.2	G108 Y111 V127 E130 F254 A337 V338 Y343 V344 A345	G108-L341 WeakPolarHBondContact O-CD1 3.46Å; Y111-L341 VanDerWaalsContact CB-CD1 3.48Å; Y111-L341 HydrophobicContact CD1-CD1 4.25Å; Y111-L341 HydrophobicContact CG-CD1 4.04Å; V127-L341 HydrophobicContact CG2-CD1 4.23Å; E130-L341 HydrophobicContact CB-CD2 4.45Å; E130-L341 HydrophobicContact CG-CD2 3.52Å; E130-L341 VanDerWaalsContact OE1-CD2 3.28Å; E130-L341 WeakPolarHBondContact OE1-CD2 3.42Å; F254-L341 HydrophobicContact CD1-CB 4.07Å; F254-L341 HydrophobicContact CD1-CD1 4.36Å; F254-L341 HydrophobicContact CD1-CD2 4.28Å; F254-L341 HydrophobicContact CD1-CG 4.49Å; F254-L341 HydrophobicContact CE1-CD1 4.23Å; F254-L341 HydrophobicContact CE1-CD2 3.95Å; F254-L341 HydrophobicContact CE1-CG 4.49Å; A337-L341 PolarHBondContact O-N 3.08Å; V338-L341 WeakPolarHBondContact O-CB 3.29Å; V338-L341 PolarHBondContact O-N 3.39Å; L341-Y343 VanDerWaalsContact C-N 3.33Å; L341-V344 PolarHBondContact O-N 3.39Å; L341-A345 WeakPolarHBondContact O-CB 3.44Å; L341-A345 PolarHBondContact O-N 3.11Å
342	F	86.8	Confident	85.1	Confident	0 Å²	0	18.4 Å²	18.4	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-67.1	-37.7	177.2	-62.2	-22.2	0	0	0	112.1	E130 L131 V338 A345 S346 L351 A368 L372	E130-F342 HydrophobicContact CG-CE1 4.42Å; L131-F342 HydrophobicContact CB-CE1 3.92Å; L131-F342 HydrophobicContact CB-CZ 4.01Å; L131-F342 HydrophobicContact CD1-CD1 4.47Å; L131-F342 HydrophobicContact CD1-CD2 4.21Å; L131-F342 HydrophobicContact CD1-CE1 3.81Å; L131-F342 HydrophobicContact CD1-CE2 3.49Å; L131-F342 VanDerWaalsContact CD1-CE2 3.49Å; L131-F342 HydrophobicContact CD1-CZ 3.28Å; L131-F342 HydrophobicContact CG-CE1 4.47Å; L131-F342 HydrophobicContact CG-CZ 4.26Å; V338-F342 HydrophobicContact CG1-CD2 3.87Å; V338-F342 HydrophobicContact CG1-CE1 4.08Å; V338-F342 HydrophobicContact CG1-CE2 3.31Å; V338-F342 HydrophobicContact CG1-CG 4.45Å; V338-F342 HydrophobicContact CG1-CZ 3.4Å; V338-F342 VanDerWaalsContact CG1-CZ 3.4Å; V338-F342 PolarHBondContact O-N 2.74Å; F342-A345 PolarHBondContact O-N 2.72Å; F342-S346 WeakPolarHBondContact O-CB 3.44Å; F342-S346 PolarHBondContact O-N 3.01Å; F342-L351 HydrophobicContact CB-CD1 4.02Å; F342-L351 HydrophobicContact CD1-CD1 3.96Å; F342-L351 HydrophobicContact CG-CD1 4.25Å; F342-A368 HydrophobicContact CB-CB 4.04Å; F342-A368 HydrophobicContact CD2-CB 4.3Å; F342-L372 HydrophobicContact CE2-CD1 4.49Å
343	Y	82.6	Confident	84.9	Confident	6 Å²	6	23.9 Å²	23.9	2%	0.024	13%	0.133	C	C	.	.	H	α-helix	trans	-56.4	-51	172.1	-179.8	-89.8	0	0	0	112	L40 S339 R340 L341 S346 R347 S356 I358 E497	L40-Y343 HydrophobicContact CD1-CE1 4.13Å; S339-Y343 VanDerWaalsContact O-CB 3.26Å; S339-Y343 WeakPolarHBondContact O-CB 3.42Å; S339-Y343 PolarHBondContact O-N 3.14Å; R340-Y343 WeakPolarHBondContact O-CB 3.3Å; R340-Y343 PolarHBondContact O-N 3.38Å; L341-Y343 VanDerWaalsContact C-N 3.33Å; Y343-S346 PolarHBondContact O-N 3.34Å; Y343-R347 PolarHBondContact O-N 3.16Å; Y343-S356 WeakPolarHBondContact CD2-O 3.36Å; Y343-S356 WeakPolarHBondContact CE2-O 3.48Å; Y343-I358 HydrophobicContact CE2-CD1 3.98Å; Y343-I358 HydrophobicContact CE2-CG1 3.85Å; Y343-E497 WeakPolarHBondContact OH-CG 3.43Å; Y343-E497 PolarHBondContact OH-OE1 3.04Å; Y343-E497 PolarHBondContact OH-OE2 3.02Å
344	V	83.9	Confident	84.9	Confident	4 Å²	4	24.3 Å²	24.3	2%	0.024	13%	0.133	C	C	.	.	H	α-helix	trans	-65.9	-43.5	179.2	172.6	0	0	0	0	111.5	Y111 R340 L341 S346 R347 E348	Y111-V344 HydrophobicContact CD1-CG1 4.18Å; Y111-V344 HydrophobicContact CE1-CG1 4.02Å; R340-V344 WeakPolarHBondContact O-CB 3.39Å; R340-V344 VanDerWaalsContact O-CG2 3.29Å; R340-V344 WeakPolarHBondContact O-CG2 3.15Å; R340-V344 PolarHBondContact O-N 3.24Å; L341-V344 PolarHBondContact O-N 3.39Å; V344-S346 VanDerWaalsContact C-N 3.28Å; V344-S346 PolarHBondContact O-N 3.45Å; V344-R347 WeakPolarHBondContact O-CB 3.45Å; V344-R347 PolarHBondContact O-N 2.94Å; V344-E348 WeakPolarHBondContact O-CG 3.38Å; V344-E348 PolarHBondContact O-N 3.13Å
345	A	87.8	Confident	84.9	Confident	0 Å²	0	24.3 Å²	24.3	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-65.3	-33.4	179.1	0	0	0	0	0	112.7	Y111 V127 L341 F342 G349 H350 L351	Y111-A345 HydrophobicContact CE1-CB 4.1Å; Y111-A345 HydrophobicContact CE2-CB 4.36Å; V127-A345 HydrophobicContact CB-CB 4.32Å; V127-A345 HydrophobicContact CG1-CB 3.76Å; V127-A345 HydrophobicContact CG2-CB 3.78Å; L341-A345 WeakPolarHBondContact O-CB 3.44Å; L341-A345 PolarHBondContact O-N 3.11Å; F342-A345 PolarHBondContact O-N 2.72Å; A345-G349 PolarHBondContact O-N 3.43Å; A345-H350 WeakPolarHBondContact O-CB 2.96Å; A345-H350 PolarHBondContact O-N 3.25Å; A345-L351 HydrophobicContact CB-CD1 3.84Å; A345-L351 HydrophobicContact CB-CG 4.09Å; A345-L351 PolarHBondContact O-N 3.28Å
346	S	87.4	Confident	84.8	Confident	6 Å²	6	25 Å²	25	4%	0.042	14%	0.136	C	C	.	.	H	α-helix	trans	-68.2	-42.2	172.4	-177.7	0	0	0	0	111.8	F342 Y343 V344 E348 G349 P352 E353 S356	F342-S346 WeakPolarHBondContact O-CB 3.44Å; F342-S346 PolarHBondContact O-N 3.01Å; Y343-S346 PolarHBondContact O-N 3.34Å; V344-S346 VanDerWaalsContact C-N 3.28Å; V344-S346 PolarHBondContact O-N 3.45Å; S346-E348 VanDerWaalsContact C-N 3.28Å; S346-E348 PolarHBondContact O-N 3.37Å; S346-G349 WeakPolarHBondContact O-CA 3.29Å; S346-G349 PolarHBondContact O-N 3.47Å; S346-P352 PolarHBondContact OG-O 3.34Å; S346-E353 WeakPolarHBondContact OG-CA 3.4Å; S346-S356 WeakPolarHBondContact CB-OG 3.03Å; S346-S356 WeakPolarHBondContact OG-CB 3.46Å; S346-S356 PolarHBondContact OG-N 3.38Å; S346-S356 VanDerWaalsContact OG-N 3.14Å; S346-S356 PolarHBondContact OG-OG 3.43Å
347	R	84.6	Confident	85	Confident	82 Å²	82	24.1 Å²	24.1	31%	0.309	13%	0.133	S	C	.	.	H	α-helix	trans	-60.7	-35.7	175	-171.6	177.9	69.7	-168.3	0.6	112.9	E257 Y343 V344 G349	E257-R347 IonicContact OE1-NH2 2.68Å; E257-R347 PolarHBondContact OE1-NH2 3.3Å; E257-R347 IonicContact OE2-NH1 3.95Å; E257-R347 IonicContact OE2-NH2 2.62Å; Y343-R347 PolarHBondContact O-N 3.16Å; V344-R347 WeakPolarHBondContact O-CB 3.45Å; V344-R347 PolarHBondContact O-N 2.94Å; R347-G349 PolarHBondContact O-N 3.2Å
348	E	87.8	Confident	85.3	Confident	76 Å²	76	24.4 Å²	24.4	36%	0.355	13%	0.133	S	C	.	.	T	Hydrogen-bonded Turn	trans	-79.3	5.4	174.2	-63.3	-67.4	157.7	0	0	113.1	Y111 L115 V344 S346 H350	Y111-E348 HydrophobicContact CE1-CB 4.49Å; Y111-E348 HydrophobicContact CE1-CG 4.1Å; Y111-E348 WeakPolarHBondContact OH-CB 3.4Å; L115-E348 HydrophobicContact CD2-CB 4.5Å; L115-E348 HydrophobicContact CD2-CG 4Å; V344-E348 WeakPolarHBondContact O-CG 3.38Å; V344-E348 PolarHBondContact O-N 3.13Å; S346-E348 VanDerWaalsContact C-N 3.28Å; S346-E348 PolarHBondContact O-N 3.37Å; E348-H350 VanDerWaalsContact C-N 3.29Å; E348-H350 PolarHBondContact O-N 2.95Å
349	G	86.8	Confident	85.5	Confident	46 Å²	46	25 Å²	25	47%	0.474	14%	0.136	S	C	.	.	T	Hydrogen-bonded Turn	trans	76.1	7.8	177	0	0	0	0	0	115.2	A345 S346 R347 I468	A345-G349 PolarHBondContact O-N 3.43Å; S346-G349 WeakPolarHBondContact O-CA 3.29Å; S346-G349 PolarHBondContact O-N 3.47Å; R347-G349 PolarHBondContact O-N 3.2Å; G349-I468 VanDerWaalsContact O-CD1 3.27Å; G349-I468 WeakPolarHBondContact O-CD1 3.12Å
350	H	89.4	Confident	85.5	Confident	14 Å²	14	27.9 Å²	27.9	7%	0.065	15%	0.153	C	C	.	.	S	Bend	trans	-86.7	-14	179.4	-73.5	165.2	0	0	0	113.9	Y111 P120 F124 A345 E348	Y111-H350 AromaticContact CE2-ND1 3.57Å; Y111-H350 AromaticContact CZ-ND1 3.61Å; Y111-H350 PolarHBondContact OH-ND1 2.91Å; P120-H350 PolarHBondContact O-CE1 3.32Å; F124-H350 HydrophobicContact CD2-CB 3.93Å; F124-H350 WeakPolarHBondContact CD2-O 3.33Å; F124-H350 WeakPolarHBondContact CE2-O 3.15Å; A345-H350 WeakPolarHBondContact O-CB 2.96Å; A345-H350 PolarHBondContact O-N 3.25Å; E348-H350 VanDerWaalsContact C-N 3.29Å; E348-H350 PolarHBondContact O-N 2.95Å
351	L	89.3	Confident	85.6	Confident	19 Å²	19	36.3 Å²	36.3	10%	0.099	19%	0.185	C	C	.	.	S	Bend	trans	-127.8	161.7	173	-73.8	-179.6	0	0	0	110.4	V127 L131 F342 A345 E353 L355	V127-L351 HydrophobicContact CG1-CD1 3.68Å; V127-L351 HydrophobicContact CG1-CD2 4.07Å; V127-L351 HydrophobicContact CG1-CG 3.86Å; L131-L351 HydrophobicContact CD2-CD2 4.23Å; F342-L351 HydrophobicContact CB-CD1 4.02Å; F342-L351 HydrophobicContact CD1-CD1 3.96Å; F342-L351 HydrophobicContact CG-CD1 4.25Å; A345-L351 HydrophobicContact CB-CD1 3.84Å; A345-L351 HydrophobicContact CB-CG 4.09Å; A345-L351 PolarHBondContact O-N 3.28Å; L351-E353 PolarHBondContact O-N 2.97Å; L351-L355 HydrophobicContact CB-CD1 4.19Å; L351-L355 HydrophobicContact CD1-CD1 4.04Å
352	P	87	Confident	85.3	Confident	79 Å²	79	40.5 Å²	40.5	51%	0.513	20%	0.203	S	C	.	.			trans	-58.7	134	176.8	-24.6	35.1	0	0	0	112.2	S346 I354 L355	S346-P352 PolarHBondContact OG-O 3.34Å; P352-I354 HydrophobicContact CB-CG2 4.12Å; P352-I354 PolarHBondContact O-N 2.88Å; P352-L355 WeakPolarHBondContact O-CB 3.44Å; P352-L355 PolarHBondContact O-N 3.29Å
353	E	84.5	Confident	84.9	Confident	117 Å²	117	45.3 Å²	45.3	55%	0.547	23%	0.226	S	C	.	.	G	3₁₀ helix	trans	-52.2	-30.1	-173	-166.2	-174.1	158.6	0	0	114.3	S346 L351 L355 S356 M357	S346-E353 WeakPolarHBondContact OG-CA 3.4Å; L351-E353 PolarHBondContact O-N 2.97Å; E353-L355 PolarHBondContact O-N 3.01Å; E353-L355 VanDerWaalsContact O-N 3.11Å; E353-S356 PolarHBondContact O-N 3.4Å; E353-S356 PolarHBondContact O-OG 3.29Å; E353-M357 HydrophobicContact CB-CE 4.27Å; E353-M357 HydrophobicContact CG-CE 3.91Å
354	I	86.1	Confident	84.7	Confident	14 Å²	14	45.1 Å²	45.1	7%	0.072	23%	0.225	C	C	.	.	G	3₁₀ helix	trans	-54	-30.4	175.1	-167.2	61.3	0	0	0	112.5	P352 S356 M357 P367 T485 L488 Q489 V494	P352-I354 HydrophobicContact CB-CG2 4.12Å; P352-I354 PolarHBondContact O-N 2.88Å; I354-S356 VanDerWaalsContact C-N 3.32Å; I354-S356 PolarHBondContact O-N 2.91Å; I354-M357 HydrophobicContact CD1-CE 4.42Å; I354-M357 HydrophobicContact CD1-CG 4.5Å; I354-M357 HydrophobicContact CD1-SD 3.55Å; I354-M357 VanDerWaalsContact CD1-SD 3.55Å; I354-M357 WeakPolarHBondContact O-CB 3.3Å; I354-M357 PolarHBondContact O-N 3.07Å; I354-P367 HydrophobicContact CD1-CG 4.49Å; I354-P367 HydrophobicContact CG1-CB 4.15Å; I354-P367 HydrophobicContact CG1-CG 4.32Å; I354-P367 VanDerWaalsContact O-CB 3.28Å; I354-P367 WeakPolarHBondContact O-CB 3.34Å; I354-P367 VanDerWaalsContact O-CG 3.29Å; I354-P367 WeakPolarHBondContact O-CG 3.2Å; I354-T485 HydrophobicContact CB-CG2 4.3Å; I354-T485 HydrophobicContact CD1-CG2 4.4Å; I354-L488 HydrophobicContact CD1-CB 3.99Å; I354-L488 HydrophobicContact CG1-CB 4.15Å; I354-L488 HydrophobicContact CG1-CD1 4.29Å; I354-Q489 HydrophobicContact CD1-CG 3.91Å; I354-V494 HydrophobicContact CD1-CG2 3.86Å
355	L	85.9	Confident	84.6	Confident	8 Å²	8	45.5 Å²	45.5	4%	0.042	23%	0.227	C	C	.	.	G	3₁₀ helix	trans	-76.4	-17.6	-179.2	-58.4	-174.5	0	0	0	113.4	L351 P352 E353 P367 V371	L351-L355 HydrophobicContact CB-CD1 4.19Å; L351-L355 HydrophobicContact CD1-CD1 4.04Å; P352-L355 WeakPolarHBondContact O-CB 3.44Å; P352-L355 PolarHBondContact O-N 3.29Å; E353-L355 PolarHBondContact O-N 3.01Å; E353-L355 VanDerWaalsContact O-N 3.11Å; L355-P367 HydrophobicContact CD2-CB 4.16Å; L355-V371 HydrophobicContact CD2-CB 4.37Å; L355-V371 HydrophobicContact CD2-CG2 3.7Å
356	S	83.1	Confident	84.4	Confident	15 Å²	15	46.5 Å²	46.5	11%	0.105	23%	0.233	C	C	.	.	G	3₁₀ helix	trans	-90.9	2.9	169.1	40.1	0	0	0	0	113.5	Y343 S346 E353 I354	Y343-S356 WeakPolarHBondContact CD2-O 3.36Å; Y343-S356 WeakPolarHBondContact CE2-O 3.48Å; S346-S356 WeakPolarHBondContact CB-OG 3.03Å; S346-S356 WeakPolarHBondContact OG-CB 3.46Å; S346-S356 PolarHBondContact OG-N 3.38Å; S346-S356 VanDerWaalsContact OG-N 3.14Å; S346-S356 PolarHBondContact OG-OG 3.43Å; E353-S356 PolarHBondContact O-N 3.4Å; E353-S356 PolarHBondContact O-OG 3.29Å; I354-S356 VanDerWaalsContact C-N 3.32Å; I354-S356 PolarHBondContact O-N 2.91Å
357	M	86.4	Confident	84.3	Confident	1 Å²	1	46.4 Å²	46.4	1%	0.005	23%	0.232	C	C	.	.			trans	-84.7	149.8	-179.4	-60.8	-176.9	-170.9	0	0	112.3	E353 I354 T485 Q489 V494 V495	E353-M357 HydrophobicContact CB-CE 4.27Å; E353-M357 HydrophobicContact CG-CE 3.91Å; I354-M357 HydrophobicContact CD1-CE 4.42Å; I354-M357 HydrophobicContact CD1-CG 4.5Å; I354-M357 HydrophobicContact CD1-SD 3.55Å; I354-M357 VanDerWaalsContact CD1-SD 3.55Å; I354-M357 WeakPolarHBondContact O-CB 3.3Å; I354-M357 PolarHBondContact O-N 3.07Å; M357-T485 HydrophobicContact CE-CG2 4.07Å; M357-Q489 HydrophobicContact CE-CG 4.25Å; M357-Q489 HydrophobicContact SD-CG 3.45Å; M357-Q489 WeakPolarHBondContact SD-CG 3.32Å; M357-Q489 PolarHBondContact SD-NE2 3.18Å; M357-V494 HydrophobicContact CB-CB 3.84Å; M357-V494 HydrophobicContact CB-CG2 3.81Å; M357-V494 HydrophobicContact SD-CG2 4.14Å; M357-V495 CarbonylContact C-O 3.6Å; M357-V495 VanDerWaalsContact CA-O 3.31Å; M357-V495 WeakPolarHBondContact CA-O 3.5Å; M357-V495 WeakPolarHBondContact CB-O 3.46Å
358	I	83.6	Confident	84.2	Confident	9 Å²	9	42.5 Å²	42.5	5%	0.046	22%	0.218	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-115.6	138	-175.7	-56.4	175.5	0	0	0	109.1	V38 Y343 V360 H363 V494 V495	V38-I358 HydrophobicContact CG1-CD1 4.24Å; Y343-I358 HydrophobicContact CE2-CD1 3.98Å; Y343-I358 HydrophobicContact CE2-CG1 3.85Å; I358-V360 PolarHBondContact O-N 2.73Å; I358-H363 VanDerWaalsContact CG2-C 3.5Å; I358-H363 HydrophobicContact CG2-CB 4.38Å; I358-V494 CarbonylContact O-C 3.58Å; I358-V494 VanDerWaalsContact O-CA 3.27Å; I358-V494 WeakPolarHBondContact O-CA 3.49Å; I358-V495 PolarHBondContact N-O 3.38Å; I358-V495 PolarHBondContact O-N 3.2Å
359	H	85.8	Confident	84	Confident	14 Å²	14	39.2 Å²	39.2	7%	0.065	20%	0.202	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-66.7	129.6	174.9	-172.9	-46.6	0	0	0	111.1	R361 K362 H363 T364 L366 L492 E493 V494	H359-R361 PolarHBondContact ND1-N 3.22Å; H359-R361 PolarHBondContact O-N 3.46Å; H359-K362 HydrophobicContact CB-CB 4.27Å; H359-K362 PolarHBondContact O-N 3.01Å; H359-H363 VanDerWaalsContact O-CA 3.32Å; H359-H363 WeakPolarHBondContact O-CA 3.44Å; H359-H363 PolarHBondContact O-N 3Å; H359-T364 PolarHBondContact N-O 3.46Å; H359-L366 HydrophobicContact CB-CB 4.45Å; H359-L492 PolarHBondContact CD2-O 3.07Å; H359-E493 WeakPolarHBondContact CA-O 3.46Å; H359-E493 IonicContact CE1-OE2 3.39Å; H359-E493 PolarHBondContact CE1-OE2 3.47Å; H359-E493 VanDerWaalsContact CE1-OE2 3.31Å; H359-V494 HydrophobicContact CB-CG1 4.24Å
360	V	82.9	Confident	84.1	Confident	65 Å²	65	40.6 Å²	40.6	39%	0.394	20%	0.198	S	C	.	.	T	Hydrogen-bonded Turn	trans	-57.9	-52.1	-172.5	177.3	0	0	0	0	112.6	I358 H363 E493 V495	I358-V360 PolarHBondContact O-N 2.73Å; V360-H363 PolarHBondContact O-CE1 3.41Å; V360-H363 VanDerWaalsContact O-CE1 3.29Å; V360-E493 HydrophobicContact CB-CG 4.32Å; V360-E493 HydrophobicContact CG2-CG 4.36Å; V360-E493 WeakPolarHBondContact CG2-O 3.36Å; V360-E493 PolarHBondContact N-O 3.44Å; V360-V495 HydrophobicContact CG2-CB 4.37Å; V360-V495 HydrophobicContact CG2-CG1 3.61Å; V360-V495 HydrophobicContact CG2-CG2 3.92Å
361	R	81.3	Confident	83.9	Confident	188 Å²	188	42.4 Å²	42.4	71%	0.709	21%	0.21	S	C	*	.	T	Hydrogen-bonded Turn	trans	-78	-34.3	-177	-55.5	-177.2	-166.5	-157.9	-0.2	114.6	H359 E493	H359-R361 PolarHBondContact ND1-N 3.22Å; H359-R361 PolarHBondContact O-N 3.46Å; R361-E493 IonicContact CZ-OE1 3.8Å; R361-E493 IonicContact CZ-OE2 3.74Å; R361-E493 IonicContact NE-OE1 3.05Å; R361-E493 PolarHBondContact NE-OE1 2.7Å; R361-E493 IonicContact NE-OE2 2.68Å; R361-E493 PolarHBondContact NE-OE2 3.36Å; R361-E493 IonicContact NH2-OE1 3.97Å; R361-E493 PolarHBondContact NH2-OE1 2.81Å; R361-E493 IonicContact NH2-OE2 3.83Å
362	K	77.3	Confident	83.8	Confident	88 Å²	88	41.6 Å²	41.6	38%	0.383	21%	0.206	S	C	.	.	T	Hydrogen-bonded Turn	trans	-99.3	-17	-168.7	-68.2	172.8	174.9	169.3	0	113.3	M182 H359 T364	M182-K362 WeakPolarHBondContact O-CB 3.45Å; M182-K362 WeakPolarHBondContact O-CD 3.14Å; M182-K362 WeakPolarHBondContact O-CG 3.45Å; H359-K362 HydrophobicContact CB-CB 4.27Å; H359-K362 PolarHBondContact O-N 3.01Å; K362-T364 HydrophobicContact CB-CG2 4.19Å; K362-T364 PolarHBondContact O-N 3.07Å
363	H	78.6	Confident	84	Confident	101 Å²	101	40.3 Å²	40.3	47%	0.468	19%	0.193	S	C	.	.			trans	51.6	40.7	-174.1	-53.6	-73.4	0	0	0	112.7	I358 H359 V360	I358-H363 VanDerWaalsContact CG2-C 3.5Å; I358-H363 HydrophobicContact CG2-CB 4.38Å; H359-H363 VanDerWaalsContact O-CA 3.32Å; H359-H363 WeakPolarHBondContact O-CA 3.44Å; H359-H363 PolarHBondContact O-N 3Å; V360-H363 PolarHBondContact O-CE1 3.41Å; V360-H363 VanDerWaalsContact O-CE1 3.29Å
364	T	80.1	Confident	84.4	Confident	1 Å²	1	37.9 Å²	37.9	1%	0.006	19%	0.188	C	C	.	.			trans	-114.5	144.9	-179.2	51	0	0	0	0	110.8	S181 V184 H359 K362 L366	S181-T364 PolarHBondContact O-OG1 3.01Å; V184-T364 HydrophobicContact CG2-CG2 3.82Å; H359-T364 PolarHBondContact N-O 3.46Å; K362-T364 HydrophobicContact CB-CG2 4.19Å; K362-T364 PolarHBondContact O-N 3.07Å; T364-L366 PolarHBondContact O-N 2.91Å
365	P	80.1	Confident	84.6	Confident	12 Å²	12	39.3 Å²	39.3	8%	0.078	20%	0.195	C	C	.	.			trans	-77.2	64.5	174.5	33.2	-36.7	0	0	0	111	A368 V369	P365-A368 HydrophobicContact CB-CB 4.5Å; P365-A368 PolarHBondContact O-N 2.73Å; P365-V369 PolarHBondContact O-N 2.97Å
366	L	84	Confident	84.8	Confident	21 Å²	21	39 Å²	39	11%	0.11	19%	0.193	C	C	.	.	H	α-helix	trans	-56.2	-47.2	-172.5	177.7	62.8	0	0	0	113.9	S181 H359 T364 A368 V369 I370 L492 V494	S181-L366 VanDerWaalsContact CB-CD1 3.45Å; S181-L366 WeakPolarHBondContact OG-CD1 3.28Å; H359-L366 HydrophobicContact CB-CB 4.45Å; T364-L366 PolarHBondContact O-N 2.91Å; L366-A368 VanDerWaalsContact C-N 3.3Å; L366-A368 PolarHBondContact O-N 3.23Å; L366-V369 PolarHBondContact O-N 2.95Å; L366-V369 VanDerWaalsContact O-N 3.13Å; L366-I370 HydrophobicContact CD1-CD1 3.75Å; L366-I370 HydrophobicContact CD1-CG1 3.93Å; L366-I370 HydrophobicContact CD2-CD1 4.19Å; L366-I370 HydrophobicContact CG-CD1 3.64Å; L366-I370 HydrophobicContact CG-CG1 4.24Å; L366-I370 WeakPolarHBondContact O-CG1 3.43Å; L366-I370 PolarHBondContact O-N 3.27Å; L366-L492 HydrophobicContact CD2-CB 4.2Å; L366-L492 HydrophobicContact CD2-CD2 4Å; L366-V494 HydrophobicContact CB-CG1 4.49Å
367	P	86.5	Confident	85.3	Confident	5 Å²	5	39.8 Å²	39.8	3%	0.032	20%	0.196	C	C	.	.	H	α-helix	trans	-62.4	-37	-176.2	-23.6	36.4	0	0	0	112.8	I354 L355 V369 I370 V371 L492 V494	I354-P367 HydrophobicContact CD1-CG 4.49Å; I354-P367 HydrophobicContact CG1-CB 4.15Å; I354-P367 HydrophobicContact CG1-CG 4.32Å; I354-P367 VanDerWaalsContact O-CB 3.28Å; I354-P367 WeakPolarHBondContact O-CB 3.34Å; I354-P367 VanDerWaalsContact O-CG 3.29Å; I354-P367 WeakPolarHBondContact O-CG 3.2Å; L355-P367 HydrophobicContact CD2-CB 4.16Å; P367-V369 VanDerWaalsContact C-N 3.32Å; P367-V369 PolarHBondContact O-N 3.41Å; P367-I370 PolarHBondContact O-N 3.03Å; P367-V371 WeakPolarHBondContact O-CG2 3.29Å; P367-V371 PolarHBondContact O-N 3.41Å; P367-V371 VanDerWaalsContact O-N 3.08Å; P367-L492 HydrophobicContact CB-CD1 4.28Å; P367-L492 HydrophobicContact CG-CD1 3.95Å; P367-V494 HydrophobicContact CG-CB 4.47Å; P367-V494 HydrophobicContact CG-CG1 3.95Å; P367-V494 HydrophobicContact CG-CG2 4.15Å
368	A	82.4	Confident	85.5	Confident	0 Å²	0	44.9 Å²	44.9	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-62.8	-37.5	176.9	0	0	0	0	0	112.6	F342 P365 L366	F342-A368 HydrophobicContact CB-CB 4.04Å; F342-A368 HydrophobicContact CD2-CB 4.3Å; P365-A368 HydrophobicContact CB-CB 4.5Å; P365-A368 PolarHBondContact O-N 2.73Å; L366-A368 VanDerWaalsContact C-N 3.3Å; L366-A368 PolarHBondContact O-N 3.23Å
369	V	83.7	Confident	85.8	Confident	6 Å²	6	46 Å²	46	4%	0.036	23%	0.227	C	C	.	.	H	α-helix	trans	-71.6	-42.4	176.5	-179.2	0	0	0	0	110.7	M177 V335 P365 L366 P367 V371 L372 H373	M177-V369 HydrophobicContact CB-CG1 4.17Å; M177-V369 HydrophobicContact SD-CG1 3.64Å; V335-V369 HydrophobicContact CG1-CG1 4.03Å; V335-V369 HydrophobicContact CG1-CG2 4.27Å; P365-V369 PolarHBondContact O-N 2.97Å; L366-V369 PolarHBondContact O-N 2.95Å; L366-V369 VanDerWaalsContact O-N 3.13Å; P367-V369 VanDerWaalsContact C-N 3.32Å; P367-V369 PolarHBondContact O-N 3.41Å; V369-V371 PolarHBondContact O-N 3.33Å; V369-L372 PolarHBondContact O-N 2.87Å; V369-H373 PolarHBondContact O-N 2.71Å
370	I	87	Confident	86	Confident	75 Å²	75	45.3 Å²	45.3	39%	0.385	22%	0.224	S	C	.	.	H	α-helix	trans	-62	-41.4	-179.2	-70.1	174.8	0	0	0	111.7	L366 P367 L372 H373 P374 L492	L366-I370 HydrophobicContact CD1-CD1 3.75Å; L366-I370 HydrophobicContact CD1-CG1 3.93Å; L366-I370 HydrophobicContact CD2-CD1 4.19Å; L366-I370 HydrophobicContact CG-CD1 3.64Å; L366-I370 HydrophobicContact CG-CG1 4.24Å; L366-I370 WeakPolarHBondContact O-CG1 3.43Å; L366-I370 PolarHBondContact O-N 3.27Å; P367-I370 PolarHBondContact O-N 3.03Å; I370-L372 VanDerWaalsContact C-N 3.29Å; I370-L372 PolarHBondContact O-N 3.05Å; I370-H373 PolarHBondContact O-N 2.65Å; I370-P374 WeakPolarHBondContact O-CD 3.44Å; I370-L492 HydrophobicContact CD1-CD1 4.19Å; I370-L492 HydrophobicContact CD1-CD2 3.52Å
371	V	87.3	Confident	86.3	Confident	53 Å²	53	46.8 Å²	46.8	32%	0.321	23%	0.225	S	C	.	.	H	α-helix	trans	-65.8	-33	179.9	170.9	0	0	0	0	112.4	L131 L355 P367 V369 H373 P374 L375	L131-V371 HydrophobicContact CD1-CG1 3.99Å; L355-V371 HydrophobicContact CD2-CB 4.37Å; L355-V371 HydrophobicContact CD2-CG2 3.7Å; P367-V371 WeakPolarHBondContact O-CG2 3.29Å; P367-V371 PolarHBondContact O-N 3.41Å; P367-V371 VanDerWaalsContact O-N 3.08Å; V369-V371 PolarHBondContact O-N 3.33Å; V371-H373 VanDerWaalsContact C-N 3.33Å; V371-H373 PolarHBondContact O-N 3.37Å; V371-P374 WeakPolarHBondContact O-CD 3.5Å; V371-L375 HydrophobicContact CG1-CD1 4.46Å
372	L	86.6	Confident	86.4	Confident	2 Å²	2	41.8 Å²	41.8	1%	0.01	22%	0.219	C	C	.	.	H	α-helix	trans	-70.4	-31.5	179.9	-174	62.5	0	0	0	112.6	R135 P136 M177 V335 V338 F342 V369 I370 T376	R135-L372 HydrophobicContact CB-CD1 3.88Å; P136-L372 HydrophobicContact CG-CD1 4.08Å; M177-L372 HydrophobicContact CE-CB 4.5Å; M177-L372 HydrophobicContact CE-CD2 4.02Å; M177-L372 HydrophobicContact CE-CG 4.1Å; V335-L372 HydrophobicContact CG2-CD2 4.42Å; V338-L372 HydrophobicContact CB-CD2 4.36Å; V338-L372 HydrophobicContact CG1-CD2 3.94Å; F342-L372 HydrophobicContact CE2-CD1 4.49Å; V369-L372 PolarHBondContact O-N 2.87Å; I370-L372 VanDerWaalsContact C-N 3.29Å; I370-L372 PolarHBondContact O-N 3.05Å; L372-T376 WeakPolarHBondContact O-CB 3.3Å; L372-T376 PolarHBondContact O-N 3.43Å; L372-T376 PolarHBondContact O-OG1 3.13Å
373	H	90.8	Very high	85.9	Confident	51 Å²	51	38.3 Å²	38.3	24%	0.236	21%	0.208	C	C	.	.	H	α-helix	trans	-60.8	-54.9	-174.1	-174.8	54.9	0	0	0	114.7	T174 M177 V369 I370 V371 L375 T376 M377	T174-H373 PolarHBondContact OG1-CE1 2.81Å; M177-H373 HydrophobicContact CG-CB 4.34Å; V369-H373 PolarHBondContact O-N 2.71Å; I370-H373 PolarHBondContact O-N 2.65Å; V371-H373 VanDerWaalsContact C-N 3.33Å; V371-H373 PolarHBondContact O-N 3.37Å; H373-L375 VanDerWaalsContact C-N 3.32Å; H373-L375 PolarHBondContact O-N 3.21Å; H373-T376 PolarHBondContact O-N 3.43Å; H373-M377 WeakPolarHBondContact CE1-CE 3.49Å; H373-M377 WeakPolarHBondContact O-CG 3.35Å; H373-M377 PolarHBondContact O-N 2.88Å
374	P	91.9	Very high	85.6	Confident	67 Å²	67	38.1 Å²	38.1	44%	0.435	21%	0.211	S	C	.	.	H	α-helix	trans	-64.1	-37.4	179.9	25.7	-33.8	0	0	0	112	I370 V371 T376 M377 I378	I370-P374 WeakPolarHBondContact O-CD 3.44Å; V371-P374 WeakPolarHBondContact O-CD 3.5Å; P374-T376 VanDerWaalsContact C-N 3.32Å; P374-T376 PolarHBondContact O-N 2.98Å; P374-M377 PolarHBondContact O-N 3.26Å; P374-I378 WeakPolarHBondContact O-CG1 3.35Å; P374-I378 PolarHBondContact O-N 2.72Å
375	L	90.6	Very high	85.2	Confident	44 Å²	44	40 Å²	40	23%	0.23	22%	0.22	C	C	.	.	H	α-helix	trans	-61.9	-42	176.2	-65.2	175	0	0	0	111.5	L131 P136 V371 H373 I378 M379	L131-L375 HydrophobicContact CD1-CD1 4.17Å; L131-L375 HydrophobicContact CG-CD1 4.28Å; L131-L375 WeakPolarHBondContact O-CD1 3.46Å; P136-L375 HydrophobicContact CB-CB 4.15Å; P136-L375 HydrophobicContact CG-CB 3.67Å; P136-L375 HydrophobicContact CG-CD1 4.42Å; V371-L375 HydrophobicContact CG1-CD1 4.46Å; H373-L375 VanDerWaalsContact C-N 3.32Å; H373-L375 PolarHBondContact O-N 3.21Å; L375-I378 PolarHBondContact O-N 3.38Å; L375-M379 WeakPolarHBondContact O-CG 3.34Å; L375-M379 PolarHBondContact O-N 3Å; L375-M379 VanDerWaalsContact O-N 3.14Å
376	T	91.5	Very high	84.7	Confident	0 Å²	0	43 Å²	43	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-68.3	-37.8	177.1	-50.5	0	0	0	0	111.5	T139 A140 L173 L372 H373 P374 M379 L380	T139-T376 HydrophobicContact CG2-CG2 3.83Å; A140-T376 HydrophobicContact CB-CG2 4.36Å; L173-T376 HydrophobicContact CD1-CG2 4.15Å; L173-T376 HydrophobicContact CD2-CG2 3.47Å; L173-T376 VanDerWaalsContact CD2-CG2 3.47Å; L173-T376 HydrophobicContact CG-CG2 4.45Å; L372-T376 WeakPolarHBondContact O-CB 3.3Å; L372-T376 PolarHBondContact O-N 3.43Å; L372-T376 PolarHBondContact O-OG1 3.13Å; H373-T376 PolarHBondContact O-N 3.43Å; P374-T376 VanDerWaalsContact C-N 3.32Å; P374-T376 PolarHBondContact O-N 2.98Å; T376-M379 PolarHBondContact O-N 3.3Å; T376-L380 WeakPolarHBondContact O-CB 3.34Å; T376-L380 PolarHBondContact O-N 3.28Å
377	M	92.8	Very high	84.2	Confident	32 Å²	32	44.5 Å²	44.5	16%	0.158	25%	0.248	C	C	.	.	H	α-helix	trans	-63.2	-42.6	174.8	-75.3	-66.3	-179	0	0	112.1	A170 L173 T174 H373 P374 M379 L380 F381	A170-M377 HydrophobicContact CB-CE 3.75Å; A170-M377 HydrophobicContact CB-SD 3.88Å; A170-M377 WeakPolarHBondContact O-CE 3.13Å; L173-M377 HydrophobicContact CD2-CE 4.03Å; L173-M377 HydrophobicContact CD2-SD 4.28Å; T174-M377 WeakPolarHBondContact OG1-CE 3.41Å; H373-M377 WeakPolarHBondContact CE1-CE 3.49Å; H373-M377 WeakPolarHBondContact O-CG 3.35Å; H373-M377 PolarHBondContact O-N 2.88Å; P374-M377 PolarHBondContact O-N 3.26Å; M377-M379 VanDerWaalsContact C-N 3.33Å; M377-M379 PolarHBondContact O-N 3.39Å; M377-L380 WeakPolarHBondContact O-CB 3.4Å; M377-L380 PolarHBondContact O-N 3.28Å; M377-L380 HydrophobicContact SD-CD2 3.99Å; M377-F381 VanDerWaalsContact O-CD2 3.25Å; M377-F381 WeakPolarHBondContact O-CD2 3.5Å; M377-F381 PolarHBondContact O-N 2.62Å; M377-F381 VanDerWaalsContact O-N 3.1Å; M377-F381 HydrophobicContact SD-CE2 4.2Å
378	I	91.4	Very high	83.6	Confident	108 Å²	108	44.6 Å²	44.6	55%	0.554	25%	0.248	S	C	*	.	H	α-helix	trans	-59.5	-46.8	175.4	-68.1	164	0	0	0	110.1	P374 L375 L380 F381 S382	P374-I378 WeakPolarHBondContact O-CG1 3.35Å; P374-I378 PolarHBondContact O-N 2.72Å; L375-I378 PolarHBondContact O-N 3.38Å; I378-L380 VanDerWaalsContact C-N 3.34Å; I378-L380 PolarHBondContact O-N 2.77Å; I378-F381 PolarHBondContact O-N 2.97Å; I378-S382 VanDerWaalsContact O-CB 3.26Å; I378-S382 WeakPolarHBondContact O-CB 3.42Å; I378-S382 PolarHBondContact O-N 3.43Å; I378-S382 PolarHBondContact O-OG 3.29Å
379	M	89.1	Confident	83.2	Confident	33 Å²	33	44.7 Å²	44.7	16%	0.163	25%	0.249	C	C	.	.	H	α-helix	trans	-63.8	-38.1	177.5	-69.3	-66.1	179.7	0	0	112.6	P136 A140 L375 T376 M377 F381 G383 L388 F391	P136-M379 HydrophobicContact CB-CB 4.4Å; P136-M379 HydrophobicContact CB-CG 3.64Å; A140-M379 HydrophobicContact CB-CB 4.05Å; L375-M379 WeakPolarHBondContact O-CG 3.34Å; L375-M379 PolarHBondContact O-N 3Å; L375-M379 VanDerWaalsContact O-N 3.14Å; T376-M379 PolarHBondContact O-N 3.3Å; M377-M379 VanDerWaalsContact C-N 3.33Å; M377-M379 PolarHBondContact O-N 3.39Å; M379-F381 PolarHBondContact O-N 2.95Å; M379-G383 PolarHBondContact O-N 3.37Å; M379-L388 HydrophobicContact CB-CD2 4.43Å; M379-L388 HydrophobicContact SD-CD2 4.07Å; M379-F391 HydrophobicContact CE-CE1 4.31Å
380	L	90.9	Very high	82.8	Confident	0 Å²	0	45.8 Å²	45.8	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-60.9	-42.1	177.8	173.8	64	0	0	0	112.5	L144 T169 A170 T376 M377 I378	L144-L380 HydrophobicContact CD1-CD1 4.26Å; L144-L380 HydrophobicContact CD2-CD1 3.42Å; L144-L380 VanDerWaalsContact CD2-CD1 3.42Å; L144-L380 HydrophobicContact CG-CD1 3.56Å; T169-L380 HydrophobicContact CG2-CD1 3.4Å; T169-L380 VanDerWaalsContact CG2-CD1 3.4Å; T169-L380 HydrophobicContact CG2-CD2 3.84Å; T169-L380 HydrophobicContact CG2-CG 4.28Å; A170-L380 HydrophobicContact CB-CD2 3.95Å; T376-L380 WeakPolarHBondContact O-CB 3.34Å; T376-L380 PolarHBondContact O-N 3.28Å; M377-L380 WeakPolarHBondContact O-CB 3.4Å; M377-L380 PolarHBondContact O-N 3.28Å; M377-L380 HydrophobicContact SD-CD2 3.99Å; I378-L380 VanDerWaalsContact C-N 3.34Å; I378-L380 PolarHBondContact O-N 2.77Å
381	F	89.4	Confident	82.1	Confident	95 Å²	95	43.4 Å²	43.4	42%	0.417	24%	0.241	S	C	.	.	H	α-helix	trans	-86	-27.1	-178.2	-73.8	-72.1	0	0	0	113.5	K166 A170 M377 I378 M379	K166-F381 HydrophobicContact CB-CD1 4.32Å; K166-F381 HydrophobicContact CB-CE1 3.92Å; K166-F381 HydrophobicContact CD-CD1 4.06Å; K166-F381 HydrophobicContact CD-CE1 4.48Å; K166-F381 PolarHBondContact NZ-O 3.33Å; A170-F381 HydrophobicContact CB-CZ 4.42Å; M377-F381 VanDerWaalsContact O-CD2 3.25Å; M377-F381 WeakPolarHBondContact O-CD2 3.5Å; M377-F381 PolarHBondContact O-N 2.62Å; M377-F381 VanDerWaalsContact O-N 3.1Å; M377-F381 HydrophobicContact SD-CE2 4.2Å; I378-F381 PolarHBondContact O-N 2.97Å; M379-F381 PolarHBondContact O-N 2.95Å
382	S	82.1	Confident	81.8	Confident	84 Å²	84	40.9 Å²	40.9	59%	0.587	23%	0.226	S	C	*	.	H	α-helix	trans	-90.6	-28.8	-176.4	59.7	0	0	0	0	115	I378	I378-S382 VanDerWaalsContact O-CB 3.26Å; I378-S382 WeakPolarHBondContact O-CB 3.42Å; I378-S382 PolarHBondContact O-N 3.43Å; I378-S382 PolarHBondContact O-OG 3.29Å
383	G	67.8	Low	81.5	Confident	14 Å²	14	40.9 Å²	40.9	14%	0.144	23%	0.226	C	C	.	.			trans	-102.3	141.8	-168.6	0	0	0	0	0	114.4	M379	M379-G383 PolarHBondContact O-N 3.37Å
384	D	72.3	Confident	81.3	Confident	98 Å²	98	38.8 Å²	38.8	52%	0.524	22%	0.216	S	C	.	.			trans	-82.1	151.2	159.1	174.3	49.6	0	0	0	110.6	D386 S387 L388	D384-D386 PolarHBondContact O-N 2.88Å; D384-S387 PolarHBondContact O-N 2.66Å; D384-L388 WeakPolarHBondContact O-CB 3.43Å; D384-L388 VanDerWaalsContact O-CG 3.27Å; D384-L388 WeakPolarHBondContact O-CG 3.36Å; D384-L388 PolarHBondContact O-N 2.94Å
385	L	70.2	Confident	81.1	Confident	40 Å²	40	35.6 Å²	35.6	21%	0.209	20%	0.196	C	C	.	.	H	α-helix	trans	-61.6	-46.1	-170	-168.7	151.4	0	0	0	112.3	I64 V141 L388 L389	I64-L385 HydrophobicContact CD1-CD1 4.34Å; V141-L385 HydrophobicContact CG1-CD1 4.41Å; V141-L385 HydrophobicContact CG1-CD2 4.28Å; V141-L385 HydrophobicContact CG1-CG 4.07Å; L385-L388 PolarHBondContact O-N 3.14Å; L385-L389 HydrophobicContact CD2-CD1 3.58Å; L385-L389 HydrophobicContact CD2-CG 4.16Å; L385-L389 WeakPolarHBondContact O-CG 3.06Å; L385-L389 PolarHBondContact O-N 3.37Å
386	D	69.8	Low	81	Confident	74 Å²	74	34.4 Å²	34.4	40%	0.396	19%	0.188	S	C	.	.	H	α-helix	trans	-69.5	-40.3	-177.8	-74.3	-41.7	0	0	0	111.5	D384 L389 N390	D384-D386 PolarHBondContact O-N 2.88Å; D386-L389 WeakPolarHBondContact O-CB 3.49Å; D386-L389 PolarHBondContact O-N 3.48Å; D386-N390 PolarHBondContact O-N 3.24Å
387	S	73.7	Confident	81	Confident	53 Å²	53	34.8 Å²	34.8	37%	0.371	19%	0.19	S	C	.	.	H	α-helix	trans	-61.7	-45.2	174.9	-62.5	0	0	0	0	111.3	D384 L389 N390 F391	D384-S387 PolarHBondContact O-N 2.66Å; S387-L389 VanDerWaalsContact C-N 3.32Å; S387-L389 PolarHBondContact O-N 3.47Å; S387-N390 PolarHBondContact O-N 2.98Å; S387-F391 WeakPolarHBondContact O-CB 3.49Å; S387-F391 PolarHBondContact O-N 3.43Å
388	L	74.4	Confident	81	Confident	8 Å²	8	35.9 Å²	35.9	4%	0.042	20%	0.196	C	C	.	.	H	α-helix	trans	-62.3	-39	176.7	-74.5	172.8	0	0	0	112.1	A137 A140 V141 M379 D384 L385 L392	A137-L388 HydrophobicContact CB-CD2 4.1Å; A140-L388 HydrophobicContact CB-CD1 4.26Å; V141-L388 HydrophobicContact CG2-CB 3.65Å; V141-L388 HydrophobicContact CG2-CD1 4.2Å; M379-L388 HydrophobicContact CB-CD2 4.43Å; M379-L388 HydrophobicContact SD-CD2 4.07Å; D384-L388 WeakPolarHBondContact O-CB 3.43Å; D384-L388 VanDerWaalsContact O-CG 3.27Å; D384-L388 WeakPolarHBondContact O-CG 3.36Å; D384-L388 PolarHBondContact O-N 2.94Å; L385-L388 PolarHBondContact O-N 3.14Å; L388-L392 WeakPolarHBondContact O-CB 3.49Å; L388-L392 WeakPolarHBondContact O-CD2 3.48Å; L388-L392 WeakPolarHBondContact O-CG 3.46Å; L388-L392 PolarHBondContact O-N 2.93Å; L388-L392 VanDerWaalsContact O-N 3.1Å
389	L	74.1	Confident	81.1	Confident	1 Å²	1	31.2 Å²	31.2	1%	0.005	17%	0.172	C	C	.	.	H	α-helix	trans	-61.9	-52.7	174.9	-76.9	178	0	0	0	111.2	V141 Y240 Y244 L385 D386 S387 F391 L392 S393	V141-L389 HydrophobicContact CG1-CD2 3.9Å; V141-L389 HydrophobicContact CG1-CG 4.25Å; V141-L389 HydrophobicContact CG2-CD2 4.26Å; V141-L389 HydrophobicContact CG2-CG 4.29Å; Y240-L389 PolarHBondContact OH-O 2.86Å; Y244-L389 HydrophobicContact CD1-CD2 4.41Å; Y244-L389 HydrophobicContact CD2-CD2 3.57Å; Y244-L389 HydrophobicContact CE1-CD2 4.09Å; Y244-L389 HydrophobicContact CE2-CD2 3.19Å; Y244-L389 HydrophobicContact CG-CD2 4.18Å; Y244-L389 VanDerWaalsContact CZ-CD2 3.5Å; L385-L389 HydrophobicContact CD2-CD1 3.58Å; L385-L389 HydrophobicContact CD2-CG 4.16Å; L385-L389 WeakPolarHBondContact O-CG 3.06Å; L385-L389 PolarHBondContact O-N 3.37Å; D386-L389 WeakPolarHBondContact O-CB 3.49Å; D386-L389 PolarHBondContact O-N 3.48Å; S387-L389 VanDerWaalsContact C-N 3.32Å; S387-L389 PolarHBondContact O-N 3.47Å; L389-F391 VanDerWaalsContact C-N 3.32Å; L389-F391 PolarHBondContact O-N 3.42Å; L389-L392 HydrophobicContact CD2-CD2 4.5Å; L389-L392 VanDerWaalsContact O-CG 3.29Å; L389-L392 WeakPolarHBondContact O-CG 3.35Å; L389-L392 PolarHBondContact O-N 3.14Å; L389-S393 WeakPolarHBondContact O-CB 3.47Å; L389-S393 PolarHBondContact O-N 3.23Å; L389-S393 VanDerWaalsContact O-N 3.1Å; L389-S393 PolarHBondContact O-OG 2.85Å
390	N	74.3	Confident	81.4	Confident	29 Å²	29	29.8 Å²	29.8	16%	0.155	17%	0.165	C	C	.	.	H	α-helix	trans	-60.8	-45.5	-178.1	-71.3	-18.8	0	0	0	111.3	Y240 D386 S387 L392 S393 D446	Y240-N390 VanDerWaalsContact CZ-OD1 3.26Å; Y240-N390 WeakPolarHBondContact OH-CA 3.11Å; Y240-N390 PolarHBondContact OH-N 3.45Å; Y240-N390 PolarHBondContact OH-OD1 3.01Å; D386-N390 PolarHBondContact O-N 3.24Å; S387-N390 PolarHBondContact O-N 2.98Å; N390-L392 PolarHBondContact O-N 3.36Å; N390-S393 PolarHBondContact O-N 3.27Å; N390-D446 HydrophobicContact CB-CB 4.28Å
391	F	73.5	Confident	81.6	Confident	25 Å²	25	30 Å²	30	11%	0.11	17%	0.167	C	C	.	.	H	α-helix	trans	-57.9	-43.8	178	-179.1	-115.8	0	0	0	113.3	I133 M379 S387 L389 S449 I452 I456	I133-F391 HydrophobicContact CB-CE1 3.97Å; I133-F391 HydrophobicContact CB-CZ 4.32Å; I133-F391 HydrophobicContact CD1-CE1 4.22Å; I133-F391 HydrophobicContact CD1-CE2 4.39Å; I133-F391 HydrophobicContact CD1-CZ 3.69Å; I133-F391 HydrophobicContact CG1-CE1 3.77Å; I133-F391 HydrophobicContact CG1-CZ 3.66Å; I133-F391 HydrophobicContact CG2-CD1 3.61Å; I133-F391 HydrophobicContact CG2-CE1 3.18Å; I133-F391 HydrophobicContact CG2-CZ 3.76Å; M379-F391 HydrophobicContact CE-CE1 4.31Å; S387-F391 WeakPolarHBondContact O-CB 3.49Å; S387-F391 PolarHBondContact O-N 3.43Å; L389-F391 VanDerWaalsContact C-N 3.32Å; L389-F391 PolarHBondContact O-N 3.42Å; F391-S449 WeakPolarHBondContact CD2-O 3.09Å; F391-I452 HydrophobicContact CE2-CB 4.27Å; F391-I452 HydrophobicContact CE2-CG2 3.9Å; F391-I456 HydrophobicContact CE2-CD1 4.1Å; F391-I456 HydrophobicContact CZ-CD1 3.72Å
392	L	80	Confident	81.9	Confident	0 Å²	0	28.1 Å²	28.1	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-77.6	-25.9	-178.7	69.3	72.2	0	0	0	113.6	A137 A138 L388 L389 N390 R396	A137-L392 HydrophobicContact CB-CB 4.06Å; A137-L392 HydrophobicContact CB-CD2 4.04Å; A138-L392 HydrophobicContact CB-CD2 4.19Å; L388-L392 WeakPolarHBondContact O-CB 3.49Å; L388-L392 WeakPolarHBondContact O-CD2 3.48Å; L388-L392 WeakPolarHBondContact O-CG 3.46Å; L388-L392 PolarHBondContact O-N 2.93Å; L388-L392 VanDerWaalsContact O-N 3.1Å; L389-L392 HydrophobicContact CD2-CD2 4.5Å; L389-L392 VanDerWaalsContact O-CG 3.29Å; L389-L392 WeakPolarHBondContact O-CG 3.35Å; L389-L392 PolarHBondContact O-N 3.14Å; N390-L392 PolarHBondContact O-N 3.36Å; L392-R396 VanDerWaalsContact CD1-NH1 3.3Å; L392-R396 VanDerWaalsContact O-CB 3.22Å; L392-R396 WeakPolarHBondContact O-CB 3.14Å; L392-R396 PolarHBondContact O-N 3.2Å; L392-R396 VanDerWaalsContact O-N 3.17Å
393	S	81.6	Confident	82.5	Confident	2 Å²	2	24.2 Å²	24.2	1%	0.014	13%	0.134	C	C	.	.	H	α-helix	trans	-71.5	-42.7	-168.3	-77.1	0	0	0	0	112.2	Y240 L389 N390 A395 R396 W397	Y240-S393 WeakPolarHBondContact CE2-OG 3.36Å; Y240-S393 VanDerWaalsContact CZ-OG 3.24Å; Y240-S393 WeakPolarHBondContact OH-CB 3.35Å; Y240-S393 PolarHBondContact OH-OG 3.08Å; L389-S393 WeakPolarHBondContact O-CB 3.47Å; L389-S393 PolarHBondContact O-N 3.23Å; L389-S393 VanDerWaalsContact O-N 3.1Å; L389-S393 PolarHBondContact O-OG 2.85Å; N390-S393 PolarHBondContact O-N 3.27Å; S393-A395 PolarHBondContact O-N 3.24Å; S393-R396 PolarHBondContact O-N 3.07Å; S393-W397 PolarHBondContact O-N 3.42Å
394	F	85.4	Confident	83.9	Confident	7 Å²	7	23.5 Å²	23.5	3%	0.031	13%	0.127	C	C	.	.	H	α-helix	trans	-53.2	-59.4	177.9	168.7	-95.2	0	0	0	111.8	R396 W397 L398 V439 L443 T450 F454	F394-R396 VanDerWaalsContact C-N 3.3Å; F394-R396 PolarHBondContact O-N 3.28Å; F394-W397 PolarHBondContact O-N 3.08Å; F394-L398 HydrophobicContact CE1-CD2 4.1Å; F394-L398 HydrophobicContact CZ-CD2 4.11Å; F394-L398 VanDerWaalsContact O-CB 3.3Å; F394-L398 WeakPolarHBondContact O-CB 3.42Å; F394-L398 PolarHBondContact O-N 3.4Å; F394-V439 HydrophobicContact CD2-CG1 3.8Å; F394-V439 HydrophobicContact CE2-CG1 3.55Å; F394-L443 HydrophobicContact CD2-CG 4.32Å; F394-L443 HydrophobicContact CE2-CD1 4.23Å; F394-L443 HydrophobicContact CE2-CD2 4.44Å; F394-L443 HydrophobicContact CE2-CG 4.22Å; F394-T450 HydrophobicContact CB-CG2 3.65Å; F394-T450 HydrophobicContact CD1-CG2 4.3Å; F394-T450 HydrophobicContact CD2-CG2 3.38Å; F394-T450 HydrophobicContact CE2-CG2 4.1Å; F394-T450 HydrophobicContact CG-CG2 3.51Å; F394-F454 HydrophobicContact CE1-CB 3.93Å; F394-F454 AromaticContact CE1-CD2 3.92Å; F394-F454 HydrophobicContact CE1-CD2 3.92Å; F394-F454 HydrophobicContact CE1-CG 4.43Å; F394-F454 HydrophobicContact CZ-CB 4.13Å; F394-F454 AromaticContact CZ-CD2 3.67Å; F394-F454 HydrophobicContact CZ-CD2 3.67Å; F394-F454 HydrophobicContact CZ-CG 4.32Å
395	A	87.6	Confident	85.1	Confident	0 Å²	0	20.4 Å²	20.4	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-64.6	-38.4	-175.6	0	0	0	0	0	111.2	V129 I134 S393 F399	V129-A395 HydrophobicContact CG1-CB 3.64Å; I134-A395 HydrophobicContact CD1-CB 3.92Å; I134-A395 HydrophobicContact CG1-CB 4.1Å; S393-A395 PolarHBondContact O-N 3.24Å; A395-F399 WeakPolarHBondContact O-CD2 3.42Å; A395-F399 PolarHBondContact O-N 2.99Å; A395-F399 VanDerWaalsContact O-N 3.13Å
396	R	89.9	Confident	86.3	Confident	20 Å²	20	18.6 Å²	18.6	8%	0.075	11%	0.106	C	C	.	.	H	α-helix	trans	-60	-54.1	176.8	-179	-173.9	-64.5	163.8	0.3	111.6	L392 S393 F394 L398 F399 I400	L392-R396 VanDerWaalsContact CD1-NH1 3.3Å; L392-R396 VanDerWaalsContact O-CB 3.22Å; L392-R396 WeakPolarHBondContact O-CB 3.14Å; L392-R396 PolarHBondContact O-N 3.2Å; L392-R396 VanDerWaalsContact O-N 3.17Å; S393-R396 PolarHBondContact O-N 3.07Å; F394-R396 VanDerWaalsContact C-N 3.3Å; F394-R396 PolarHBondContact O-N 3.28Å; R396-L398 VanDerWaalsContact C-N 3.35Å; R396-F399 PolarHBondContact O-N 3.14Å; R396-I400 HydrophobicContact CG-CD1 3.73Å; R396-I400 WeakPolarHBondContact O-CB 3.48Å; R396-I400 VanDerWaalsContact O-CG1 3.28Å; R396-I400 WeakPolarHBondContact O-CG1 3.01Å; R396-I400 PolarHBondContact O-N 3.45Å
397	W	91.6	Very high	87.5	Confident	7 Å²	7	15.1 Å²	15.1	3%	0.027	9%	0.087	C	C	.	.	H	α-helix	trans	-67.2	-36.5	-177.6	-70.9	117.4	0	0	0	112.2	M243 S393 F394 F399 G401 F431 M438 V439	M243-W397 HydrophobicContact CB-CH2 3.98Å; M243-W397 HydrophobicContact CB-CZ2 3.6Å; M243-W397 HydrophobicContact CE-CH2 3.45Å; M243-W397 VanDerWaalsContact CE-CH2 3.45Å; M243-W397 HydrophobicContact CE-CZ2 4.24Å; M243-W397 HydrophobicContact CE-CZ3 3.9Å; S393-W397 PolarHBondContact O-N 3.42Å; F394-W397 PolarHBondContact O-N 3.08Å; W397-F399 PolarHBondContact O-N 3.31Å; W397-G401 PolarHBondContact O-N 3.33Å; W397-F431 HydrophobicContact CZ3-CE2 4.32Å; W397-F431 HydrophobicContact CZ3-CZ 4.03Å; W397-M438 HydrophobicContact CB-CB 4.06Å; W397-M438 HydrophobicContact CD2-CB 4.06Å; W397-M438 HydrophobicContact CD2-CG 4.19Å; W397-M438 HydrophobicContact CG-CB 3.7Å; W397-M438 HydrophobicContact CG-CG 4.34Å; W397-V439 HydrophobicContact CB-CG2 3.89Å
398	L	92.1	Very high	88.6	Confident	56 Å²	56	14.3 Å²	14.3	29%	0.293	8%	0.078	S	C	.	.	H	α-helix	trans	-56.8	-51	174.8	178.9	64.9	0	0	0	111.4	F394 R396 G401 L402 V439	F394-L398 HydrophobicContact CE1-CD2 4.1Å; F394-L398 HydrophobicContact CZ-CD2 4.11Å; F394-L398 VanDerWaalsContact O-CB 3.3Å; F394-L398 WeakPolarHBondContact O-CB 3.42Å; F394-L398 PolarHBondContact O-N 3.4Å; R396-L398 VanDerWaalsContact C-N 3.35Å; L398-G401 PolarHBondContact O-N 3.44Å; L398-L402 WeakPolarHBondContact O-CB 3.19Å; L398-L402 PolarHBondContact O-N 3.4Å; L398-V439 HydrophobicContact CB-CG2 3.97Å
399	F	93.9	Very high	89.6	Confident	9 Å²	9	18.7 Å²	18.7	4%	0.039	10%	0.095	C	C	.	.	H	α-helix	trans	-75.9	-32.7	-176.7	-78.4	-60.9	0	0	0	114.2	I114 V125 R126 V129 A395 R396 W397 G401 L402 A403 T457	I114-F399 HydrophobicContact CD1-CB 4.49Å; I114-F399 HydrophobicContact CD1-CD1 3.91Å; V125-F399 HydrophobicContact CG1-CZ 4Å; R126-F399 HydrophobicContact CB-CD1 3.96Å; R126-F399 HydrophobicContact CB-CE1 3.84Å; R126-F399 HydrophobicContact CB-CG 4.48Å; R126-F399 HydrophobicContact CB-CZ 4.29Å; R126-F399 HydrophobicContact CG-CD1 4.25Å; R126-F399 HydrophobicContact CG-CG 4.39Å; V129-F399 HydrophobicContact CB-CE2 4.09Å; V129-F399 HydrophobicContact CG1-CE2 4.3Å; V129-F399 HydrophobicContact CG2-CE2 4.25Å; A395-F399 WeakPolarHBondContact O-CD2 3.42Å; A395-F399 PolarHBondContact O-N 2.99Å; A395-F399 VanDerWaalsContact O-N 3.13Å; R396-F399 PolarHBondContact O-N 3.14Å; W397-F399 PolarHBondContact O-N 3.31Å; F399-G401 VanDerWaalsContact C-N 3.35Å; F399-L402 HydrophobicContact CD1-CD2 4.28Å; F399-L402 PolarHBondContact O-N 3.31Å; F399-A403 PolarHBondContact O-N 3Å; F399-T457 HydrophobicContact CE2-CG2 4.27Å; F399-T457 HydrophobicContact CZ-CG2 4.13Å
400	I	94.3	Very high	90.6	Very high	3 Å²	3	19.3 Å²	19.3	2%	0.015	10%	0.098	C	C	.	.	H	α-helix	trans	-64.4	-44.9	171	-70.7	173.9	0	0	0	109.6	Y97 W249 F250 R396 L402 A403 V404 F431	Y97-I400 HydrophobicContact CE2-CG2 4.22Å; W249-I400 HydrophobicContact CH2-CG2 4.41Å; F250-I400 HydrophobicContact CD1-CD1 4.16Å; F250-I400 HydrophobicContact CE1-CD1 3.76Å; F250-I400 HydrophobicContact CZ-CD1 4.5Å; R396-I400 HydrophobicContact CG-CD1 3.73Å; R396-I400 WeakPolarHBondContact O-CB 3.48Å; R396-I400 VanDerWaalsContact O-CG1 3.28Å; R396-I400 WeakPolarHBondContact O-CG1 3.01Å; R396-I400 PolarHBondContact O-N 3.45Å; I400-L402 VanDerWaalsContact C-N 3.33Å; I400-L402 PolarHBondContact O-N 3.02Å; I400-A403 PolarHBondContact O-N 3.05Å; I400-V404 WeakPolarHBondContact O-CG2 3.4Å; I400-V404 PolarHBondContact O-N 3.44Å; I400-F431 HydrophobicContact CG2-CE1 3.57Å; I400-F431 HydrophobicContact CG2-CZ 3.82Å
401	G	95.5	Very high	91.6	Very high	6 Å²	6	19.3 Å²	19.3	6%	0.062	10%	0.096	C	C	.	.	H	α-helix	trans	-58.9	-43	174.9	0	0	0	0	0	112.2	W397 L398 F399 V404 A405	W397-G401 PolarHBondContact O-N 3.33Å; L398-G401 PolarHBondContact O-N 3.44Å; F399-G401 VanDerWaalsContact C-N 3.35Å; G401-V404 PolarHBondContact O-N 2.96Å; G401-A405 VanDerWaalsContact O-CB 3.26Å; G401-A405 WeakPolarHBondContact O-CB 3.39Å; G401-A405 PolarHBondContact O-N 3.46Å
402	L	95.5	Very high	92.5	Very high	54 Å²	54	26.2 Å²	26.2	28%	0.283	12%	0.123	S	C	.	.	H	α-helix	trans	-62.7	-43.6	175.9	-173.4	65.5	0	0	0	112	I114 F118 L398 F399 I400 V404 A405 G406	I114-L402 HydrophobicContact CD1-CD2 4.2Å; I114-L402 HydrophobicContact CG1-CD2 4.27Å; I114-L402 HydrophobicContact CG1-CG 4.44Å; I114-L402 HydrophobicContact CG2-CD2 4.26Å; F118-L402 HydrophobicContact CD2-CD1 4.12Å; F118-L402 HydrophobicContact CD2-CD2 4.32Å; F118-L402 HydrophobicContact CD2-CG 4Å; F118-L402 HydrophobicContact CE1-CD1 4.18Å; F118-L402 HydrophobicContact CE2-CD1 3.56Å; F118-L402 HydrophobicContact CE2-CD2 4.41Å; F118-L402 HydrophobicContact CE2-CG 3.61Å; F118-L402 WeakPolarHBondContact CE2-O 3.13Å; F118-L402 HydrophobicContact CZ-CD1 3.59Å; F118-L402 HydrophobicContact CZ-CG 4.17Å; L398-L402 WeakPolarHBondContact O-CB 3.19Å; L398-L402 PolarHBondContact O-N 3.4Å; F399-L402 HydrophobicContact CD1-CD2 4.28Å; F399-L402 PolarHBondContact O-N 3.31Å; I400-L402 VanDerWaalsContact C-N 3.33Å; I400-L402 PolarHBondContact O-N 3.02Å; L402-V404 PolarHBondContact O-N 3.43Å; L402-A405 PolarHBondContact O-N 3.1Å; L402-G406 PolarHBondContact O-N 3.4Å
403	A	95.9	Very high	93.2	Very high	2 Å²	2	32.4 Å²	32.4	2%	0.017	15%	0.149	C	C	.	.	H	α-helix	trans	-61.6	-43.5	177.1	0	0	0	0	0	111.9	Y97 H110 I114 F399 I400 G406 L407	Y97-A403 HydrophobicContact CE2-CB 4.49Å; H110-A403 HydrophobicContact CB-CB 4.16Å; I114-A403 HydrophobicContact CG1-CB 4.37Å; F399-A403 PolarHBondContact O-N 3Å; I400-A403 PolarHBondContact O-N 3.05Å; A403-G406 WeakPolarHBondContact O-CA 3.43Å; A403-G406 PolarHBondContact O-N 3.17Å; A403-L407 PolarHBondContact O-N 3.42Å; A403-L407 VanDerWaalsContact O-N 3.15Å
404	V	96.8	Very high	93.7	Very high	0 Å²	0	34.9 Å²	34.9	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-73.3	-36.8	178.6	179.1	0	0	0	0	112.2	Y97 I400 G401 L402 G406 L407 I408 P428 F431	Y97-V404 HydrophobicContact CD2-CG2 3.97Å; Y97-V404 HydrophobicContact CE2-CG2 3.66Å; I400-V404 WeakPolarHBondContact O-CG2 3.4Å; I400-V404 PolarHBondContact O-N 3.44Å; G401-V404 PolarHBondContact O-N 2.96Å; L402-V404 PolarHBondContact O-N 3.43Å; V404-G406 PolarHBondContact O-N 3.27Å; V404-L407 VanDerWaalsContact O-CB 3.27Å; V404-L407 WeakPolarHBondContact O-CB 3.15Å; V404-L407 PolarHBondContact O-N 2.87Å; V404-I408 PolarHBondContact O-N 2.89Å; V404-P428 HydrophobicContact CG1-CB 3.49Å; V404-P428 VanDerWaalsContact CG1-CB 3.49Å; V404-P428 WeakPolarHBondContact CG1-O 3.49Å; V404-F431 HydrophobicContact CB-CD1 4.26Å; V404-F431 HydrophobicContact CG1-CD1 4.16Å; V404-F431 HydrophobicContact CG2-CD1 3.8Å; V404-F431 HydrophobicContact CG2-CE1 3.89Å
405	A	96.3	Very high	94	Very high	33 Å²	33	38 Å²	38	27%	0.273	19%	0.187	S	C	.	.	H	α-helix	trans	-60.3	-36.3	169.4	0	0	0	0	0	111	G401 L402 L407 I408 Y409	G401-A405 VanDerWaalsContact O-CB 3.26Å; G401-A405 WeakPolarHBondContact O-CB 3.39Å; G401-A405 PolarHBondContact O-N 3.46Å; L402-A405 PolarHBondContact O-N 3.1Å; A405-L407 VanDerWaalsContact C-N 3.3Å; A405-L407 PolarHBondContact O-N 3.5Å; A405-I408 WeakPolarHBondContact O-CB 3.39Å; A405-I408 PolarHBondContact O-N 3.12Å; A405-Y409 PolarHBondContact O-N 3.25Å
406	G	95.6	Very high	94.2	Very high	1 Å²	1	45.5 Å²	45.5	1%	0.01	23%	0.227	C	C	.	.	H	α-helix	trans	-60.2	-36.1	172	0	0	0	0	0	113.3	L402 A403 V404 Y409 L410	L402-G406 PolarHBondContact O-N 3.4Å; A403-G406 WeakPolarHBondContact O-CA 3.43Å; A403-G406 PolarHBondContact O-N 3.17Å; V404-G406 PolarHBondContact O-N 3.27Å; G406-Y409 PolarHBondContact O-N 2.94Å; G406-L410 WeakPolarHBondContact O-CG 3.32Å; G406-L410 PolarHBondContact O-N 2.94Å
407	L	96.3	Very high	94.3	Very high	1 Å²	1	47 Å²	47	1%	0.005	24%	0.236	C	C	.	.	H	α-helix	trans	-61.6	-46.7	172.4	-179.1	67.2	0	0	0	111.8	E99 L100 A403 V404 A405 Y409 L410 R411 P428	E99-L407 HydrophobicContact CB-CD1 4.42Å; E99-L407 HydrophobicContact CB-CD2 4.28Å; E99-L407 HydrophobicContact CG-CD1 3.74Å; E99-L407 HydrophobicContact CG-CD2 4.3Å; E99-L407 VanDerWaalsContact OE1-CD1 3.29Å; E99-L407 WeakPolarHBondContact OE1-CD1 3.49Å; L100-L407 HydrophobicContact CD1-CB 4.13Å; L100-L407 HydrophobicContact CD2-CB 3.86Å; L100-L407 HydrophobicContact CD2-CD1 3.53Å; L100-L407 HydrophobicContact CD2-CG 4.26Å; L100-L407 HydrophobicContact CG-CB 3.97Å; L100-L407 HydrophobicContact CG-CD1 3.73Å; L100-L407 HydrophobicContact CG-CD2 4.42Å; L100-L407 HydrophobicContact CG-CG 4.24Å; A403-L407 PolarHBondContact O-N 3.42Å; A403-L407 VanDerWaalsContact O-N 3.15Å; V404-L407 VanDerWaalsContact O-CB 3.27Å; V404-L407 WeakPolarHBondContact O-CB 3.15Å; V404-L407 PolarHBondContact O-N 2.87Å; A405-L407 VanDerWaalsContact C-N 3.3Å; A405-L407 PolarHBondContact O-N 3.5Å; L407-Y409 VanDerWaalsContact C-N 3.29Å; L407-Y409 PolarHBondContact O-N 3.44Å; L407-L410 PolarHBondContact O-N 3.4Å; L407-R411 WeakPolarHBondContact O-CG 3.43Å; L407-R411 PolarHBondContact O-N 3.03Å; L407-P428 HydrophobicContact CD2-CB 4.12Å; L407-P428 HydrophobicContact CD2-CG 4.34Å
408	I	96.4	Very high	94.3	Very high	37 Å²	37	53.2 Å²	53.2	19%	0.19	27%	0.265	C	S	.	.	H	α-helix	trans	-60.5	-43.3	177	-59.3	171.7	0	0	0	109.6	V404 A405 L410 R411 Y412 P428 A429	V404-I408 PolarHBondContact O-N 2.89Å; A405-I408 WeakPolarHBondContact O-CB 3.39Å; A405-I408 PolarHBondContact O-N 3.12Å; I408-L410 PolarHBondContact O-N 2.85Å; I408-R411 VanDerWaalsContact O-CB 3.31Å; I408-R411 WeakPolarHBondContact O-CB 3.4Å; I408-R411 PolarHBondContact O-N 3.38Å; I408-Y412 HydrophobicContact CG2-CD2 4.19Å; I408-Y412 HydrophobicContact CG2-CE2 3.67Å; I408-Y412 WeakPolarHBondContact O-CD2 3.49Å; I408-Y412 PolarHBondContact O-N 3.19Å; I408-P428 HydrophobicContact CD1-CB 4.21Å; I408-P428 HydrophobicContact CG1-CB 3.9Å; I408-P428 HydrophobicContact CG1-CG 4.08Å; I408-A429 HydrophobicContact CD1-CB 4.28Å
409	Y	95.9	Very high	94.4	Very high	99 Å²	99	52.2 Å²	52.2	39%	0.388	26%	0.257	S	S	.	.	H	α-helix	trans	-62.3	-43.4	176.1	178.2	-101.5	0	0	0	112.9	V117 A405 G406 L407 R411 Y412 K413	V117-Y409 HydrophobicContact CG1-CD1 3.62Å; V117-Y409 HydrophobicContact CG1-CE1 4.18Å; V117-Y409 HydrophobicContact CG1-CG 4.46Å; A405-Y409 PolarHBondContact O-N 3.25Å; G406-Y409 PolarHBondContact O-N 2.94Å; L407-Y409 VanDerWaalsContact C-N 3.29Å; L407-Y409 PolarHBondContact O-N 3.44Å; Y409-R411 PolarHBondContact O-N 2.94Å; Y409-Y412 PolarHBondContact O-N 2.96Å; Y409-Y412 VanDerWaalsContact O-N 3.11Å; Y409-K413 HydrophobicContact CD1-CD 4.39Å; Y409-K413 HydrophobicContact CE1-CB 4.25Å; Y409-K413 HydrophobicContact CE1-CD 3.41Å; Y409-K413 VanDerWaalsContact CE1-CD 3.41Å; Y409-K413 HydrophobicContact CE1-CG 4.5Å; Y409-K413 HydrophobicContact CE2-CD 4.34Å; Y409-K413 PolarHBondContact O-N 3Å; Y409-K413 WeakPolarHBondContact OH-CD 3.38Å; Y409-K413 PolarHBondContact OH-NZ 3.21Å
410	L	94.8	Very high	94.3	Very high	15 Å²	15	54.1 Å²	54.1	8%	0.079	27%	0.27	C	S	.	.	H	α-helix	trans	-61.4	-31.9	175.7	-75.9	174	0	0	0	112.3	L100 I104 V117 G406 L407 I408 Y412 C414 M417 R419	L100-L410 HydrophobicContact CD2-CD1 4.24Å; I104-L410 HydrophobicContact CD1-CD1 4.19Å; V117-L410 HydrophobicContact CG2-CD1 3.54Å; V117-L410 HydrophobicContact CG2-CD2 4Å; V117-L410 HydrophobicContact CG2-CG 3.63Å; G406-L410 WeakPolarHBondContact O-CG 3.32Å; G406-L410 PolarHBondContact O-N 2.94Å; L407-L410 PolarHBondContact O-N 3.4Å; I408-L410 PolarHBondContact O-N 2.85Å; L410-Y412 VanDerWaalsContact C-N 3.29Å; L410-Y412 PolarHBondContact O-N 3.47Å; L410-C414 CarbonylContact O-C 3.58Å; L410-C414 VanDerWaalsContact O-C 3.3Å; L410-C414 WeakPolarHBondContact O-CA 3.47Å; L410-C414 PolarHBondContact O-N 3.28Å; L410-C414 VanDerWaalsContact O-O 3.12Å; L410-M417 HydrophobicContact CD1-CE 4.36Å; L410-R419 PolarHBondContact O-NH2 3.49Å
411	R	93.9	Very high	94.3	Very high	29 Å²	29	56.4 Å²	56.4	11%	0.109	28%	0.281	C	S	.	.	H	α-helix	trans	-61.7	-37.8	174.6	-73.5	-81.2	-176.2	-172.7	8.4	112.5	E99 L407 I408 Y409 K422 L425	E99-R411 IonicContact OE1-CZ 2.97Å; E99-R411 IonicContact OE1-NE 2.77Å; E99-R411 PolarHBondContact OE1-NE 3.2Å; E99-R411 IonicContact OE1-NH2 2.65Å; E99-R411 PolarHBondContact OE1-NH2 2.94Å; E99-R411 IonicContact OE2-CZ 3.76Å; E99-R411 IonicContact OE2-NE 3.92Å; E99-R411 IonicContact OE2-NH2 2.78Å; E99-R411 PolarHBondContact OE2-NH2 3.44Å; L407-R411 WeakPolarHBondContact O-CG 3.43Å; L407-R411 PolarHBondContact O-N 3.03Å; I408-R411 VanDerWaalsContact O-CB 3.31Å; I408-R411 WeakPolarHBondContact O-CB 3.4Å; I408-R411 PolarHBondContact O-N 3.38Å; Y409-R411 PolarHBondContact O-N 2.94Å; R411-K422 VanDerWaalsContact NH2-CB 3.33Å; R411-K422 VanDerWaalsContact NH2-CD 3.34Å; R411-L425 HydrophobicContact CB-CD2 4.04Å; R411-L425 HydrophobicContact CG-CD2 3.83Å
412	Y	93.6	Very high	94.3	Very high	169 Å²	169	63.1 Å²	63.1	66%	0.663	31%	0.308	S	S	*	.	H	α-helix	trans	-83.1	-43.9	178.4	-67.3	-68.8	0	0	0	113.1	I408 Y409 L410	I408-Y412 HydrophobicContact CG2-CD2 4.19Å; I408-Y412 HydrophobicContact CG2-CE2 3.67Å; I408-Y412 WeakPolarHBondContact O-CD2 3.49Å; I408-Y412 PolarHBondContact O-N 3.19Å; Y409-Y412 PolarHBondContact O-N 2.96Å; Y409-Y412 VanDerWaalsContact O-N 3.11Å; L410-Y412 VanDerWaalsContact C-N 3.29Å; L410-Y412 PolarHBondContact O-N 3.47Å
413	K	94.2	Very high	94.3	Very high	130 Å²	130	60.9 Å²	60.9	57%	0.565	30%	0.297	S	S	*	.	H	α-helix	trans	-82.1	-34.9	-173.3	-174.4	171.7	-179.1	-175.6	0	114.1	Y409 P415	Y409-K413 HydrophobicContact CD1-CD 4.39Å; Y409-K413 HydrophobicContact CE1-CB 4.25Å; Y409-K413 HydrophobicContact CE1-CD 3.41Å; Y409-K413 VanDerWaalsContact CE1-CD 3.41Å; Y409-K413 HydrophobicContact CE1-CG 4.5Å; Y409-K413 HydrophobicContact CE2-CD 4.34Å; Y409-K413 PolarHBondContact O-N 3Å; Y409-K413 WeakPolarHBondContact OH-CD 3.38Å; Y409-K413 PolarHBondContact OH-NZ 3.21Å; K413-P415 VanDerWaalsContact C-CD 3.47Å; K413-P415 WeakPolarHBondContact O-CD 3.31Å
414	C	92.8	Very high	94.4	Very high	54 Å²	54	64.2 Å²	64.2	37%	0.365	32%	0.318	S	S	.	.			trans	-126	69	-177.8	-61.1	0	0	0	0	109.6	L410 D416 M417 R419	L410-C414 CarbonylContact O-C 3.58Å; L410-C414 VanDerWaalsContact O-C 3.3Å; L410-C414 WeakPolarHBondContact O-CA 3.47Å; L410-C414 PolarHBondContact O-N 3.28Å; L410-C414 VanDerWaalsContact O-O 3.12Å; C414-D416 VanDerWaalsContact C-N 3.3Å; C414-D416 PolarHBondContact O-N 3.21Å; C414-M417 HydrophobicContact CB-CB 4.31Å; C414-M417 PolarHBondContact O-N 3.42Å; C414-R419 PolarHBondContact O-NH2 3.32Å
415	P	90.8	Very high	94.3	Very high	73 Å²	73	67.8 Å²	67.8	47%	0.474	34%	0.336	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.8	-37.9	-176.9	25.2	-33.3	0	0	0	111.9	K413 M417 R419	K413-P415 VanDerWaalsContact C-CD 3.47Å; K413-P415 WeakPolarHBondContact O-CD 3.31Å; P415-M417 VanDerWaalsContact C-N 3.28Å; P415-M417 PolarHBondContact O-N 2.85Å; P415-R419 PolarHBondContact O-NH1 3.3Å
416	D	91.8	Very high	94.3	Very high	157 Å²	157	72.1 Å²	72.1	84%	0.84	35%	0.35	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.3	1	-174.6	-53	-44.3	0	0	0	114.5	C414 H418	C414-D416 VanDerWaalsContact C-N 3.3Å; C414-D416 PolarHBondContact O-N 3.21Å; D416-H418 PolarHBondContact O-N 3.36Å
417	M	91.9	Very high	94.4	Very high	52 Å²	52	72.8 Å²	72.8	26%	0.256	35%	0.352	S	S	.	.	S	Bend	trans	-58.5	132.1	175	-174.3	177.4	69.2	0	0	110	L410 C414 P415 R419	L410-M417 HydrophobicContact CD1-CE 4.36Å; C414-M417 HydrophobicContact CB-CB 4.31Å; C414-M417 PolarHBondContact O-N 3.42Å; P415-M417 VanDerWaalsContact C-N 3.28Å; P415-M417 PolarHBondContact O-N 2.85Å; M417-R419 HydrophobicContact CE-CG 4.09Å; M417-R419 WeakPolarHBondContact O-CG 3.18Å; M417-R419 PolarHBondContact O-N 3.18Å
418	H	92.2	Very high	94.4	Very high	137 Å²	137	72.8 Å²	72.8	63%	0.634	35%	0.353	S	S	*	.			trans	-63.9	119.6	177.4	-175.7	70.6	0	0	0	110.6	D416	D416-H418 PolarHBondContact O-N 3.36Å
419	R	93.4	Very high	94.4	Very high	35 Å²	35	73.3 Å²	73.3	13%	0.132	36%	0.362	C	S	.	.			trans	-126.7	91.2	-177.4	-66.8	178.5	-176	108	1.3	109.7	E99 L410 C414 P415 M417 F421	E99-R419 IonicContact OE1-NE 3.77Å; L410-R419 PolarHBondContact O-NH2 3.49Å; C414-R419 PolarHBondContact O-NH2 3.32Å; P415-R419 PolarHBondContact O-NH1 3.3Å; M417-R419 HydrophobicContact CE-CG 4.09Å; M417-R419 WeakPolarHBondContact O-CG 3.18Å; M417-R419 PolarHBondContact O-N 3.18Å; R419-F421 PolarHBondContact O-N 3.25Å
420	P	92.8	Very high	94.4	Very high	49 Å²	49	72 Å²	72	32%	0.318	36%	0.362	S	S	.	.	S	Bend	trans	-59	-35.5	179.4	-23.1	31.9	0	0	0	112.9	E263	E263-P420 HydrophobicContact CB-CB 3.96Å; E263-P420 HydrophobicContact CB-CG 4.43Å; E263-P420 HydrophobicContact CG-CB 3.83Å; E263-P420 HydrophobicContact CG-CG 3.74Å
421	F	94	Very high	94.5	Very high	52 Å²	52	71.3 Å²	71.3	23%	0.228	36%	0.358	C	S	.	.	S	Bend	trans	-119.4	129.6	174.5	-176.8	-101.1	0	0	0	109.1	L95 A98 E99 T102 P267 R419 V423	L95-F421 HydrophobicContact CD2-CE1 4.29Å; L95-F421 HydrophobicContact CD2-CZ 3.89Å; A98-F421 HydrophobicContact CB-CD1 3.87Å; A98-F421 HydrophobicContact CB-CE1 3.77Å; E99-F421 HydrophobicContact CB-CD1 4.24Å; E99-F421 WeakPolarHBondContact CG-O 3.34Å; T102-F421 HydrophobicContact CG2-CB 4.17Å; P267-F421 HydrophobicContact CB-CD1 4.46Å; P267-F421 HydrophobicContact CB-CD2 3.76Å; P267-F421 HydrophobicContact CB-CE2 3.83Å; P267-F421 HydrophobicContact CB-CG 4.09Å; P267-F421 HydrophobicContact CB-CZ 4.21Å; P267-F421 HydrophobicContact CG-CB 3.96Å; P267-F421 HydrophobicContact CG-CD1 4.25Å; P267-F421 HydrophobicContact CG-CD2 3.8Å; P267-F421 HydrophobicContact CG-CE2 4.37Å; P267-F421 HydrophobicContact CG-CG 3.74Å; R419-F421 PolarHBondContact O-N 3.25Å; F421-V423 HydrophobicContact CD1-CG1 4.31Å; F421-V423 HydrophobicContact CE1-CG1 3.49Å; F421-V423 VanDerWaalsContact CE1-CG1 3.49Å; F421-V423 HydrophobicContact CZ-CG1 3.99Å
422	K	95.1	Very high	94.6	Very high	147 Å²	147	70.7 Å²	70.7	64%	0.639	36%	0.358	S	S	*	.			trans	-135.4	121	-172.9	157	156.9	-162.6	-175.4	0	110	E99 R411	E99-K422 WeakPolarHBondContact OE2-CA 3.42Å; R411-K422 VanDerWaalsContact NH2-CB 3.33Å; R411-K422 VanDerWaalsContact NH2-CD 3.34Å
423	V	96.1	Very high	94.6	Very high	7 Å²	7	68.9 Å²	68.9	4%	0.042	35%	0.354	C	S	.	.			trans	-96.8	150.9	174.6	-62.4	0	0	0	0	111.3	L95 E99 F421 I427	L95-V423 HydrophobicContact CB-CG1 3.91Å; E99-V423 HydrophobicContact CB-CG2 4.48Å; E99-V423 VanDerWaalsContact OE2-CG2 3.24Å; E99-V423 WeakPolarHBondContact OE2-CG2 3.26Å; E99-V423 PolarHBondContact OE2-N 2.97Å; F421-V423 HydrophobicContact CD1-CG1 4.31Å; F421-V423 HydrophobicContact CE1-CG1 3.49Å; F421-V423 VanDerWaalsContact CE1-CG1 3.49Å; F421-V423 HydrophobicContact CZ-CG1 3.99Å; V423-I427 HydrophobicContact CB-CD1 4.3Å
424	P	96.8	Very high	94.6	Very high	71 Å²	71	63.2 Å²	63.2	46%	0.461	33%	0.33	S	S	.	.			trans	-59.5	143.4	169	-23.8	34.4	0	0	0	111.7	F426 I427 P428	P424-F426 HydrophobicContact CB-CD1 3.51Å; P424-F426 HydrophobicContact CB-CE1 3.45Å; P424-F426 VanDerWaalsContact CB-CE1 3.45Å; P424-F426 HydrophobicContact CG-CD1 4.44Å; P424-F426 HydrophobicContact CG-CE1 3.9Å; P424-F426 PolarHBondContact O-N 3.09Å; P424-F426 VanDerWaalsContact O-N 3.14Å; P424-I427 WeakPolarHBondContact O-CB 3.34Å; P424-I427 PolarHBondContact O-N 3.34Å; P424-I427 VanDerWaalsContact O-N 3.1Å; P424-P428 WeakPolarHBondContact O-CD 3.46Å
425	L	95.4	Very high	94.7	Very high	75 Å²	75	60.7 Å²	60.7	39%	0.393	31%	0.313	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.2	-24.2	-175	-78	171.9	0	0	0	114.8	R411 I427 P428 A429	R411-L425 HydrophobicContact CB-CD2 4.04Å; R411-L425 HydrophobicContact CG-CD2 3.83Å; L425-I427 PolarHBondContact O-N 2.91Å; L425-P428 VanDerWaalsContact O-CD 3.28Å; L425-P428 WeakPolarHBondContact O-CD 3.35Å; L425-P428 WeakPolarHBondContact O-CG 3.34Å; L425-A429 VanDerWaalsContact O-CB 3.28Å; L425-A429 WeakPolarHBondContact O-CB 3.49Å; L425-A429 PolarHBondContact O-N 2.9Å; L425-A429 VanDerWaalsContact O-N 3.15Å
426	F	96.8	Very high	94.7	Very high	125 Å²	125	62.1 Å²	62.1	55%	0.548	32%	0.317	S	S	.	.	H	α-helix	trans	-64.8	-29.4	177.6	79.8	-96.2	0	0	0	112.1	F92 P424 L430	F92-F426 HydrophobicContact CZ-CE2 4.43Å; P424-F426 HydrophobicContact CB-CD1 3.51Å; P424-F426 HydrophobicContact CB-CE1 3.45Å; P424-F426 VanDerWaalsContact CB-CE1 3.45Å; P424-F426 HydrophobicContact CG-CD1 4.44Å; P424-F426 HydrophobicContact CG-CE1 3.9Å; P424-F426 PolarHBondContact O-N 3.09Å; P424-F426 VanDerWaalsContact O-N 3.14Å; F426-L430 VanDerWaalsContact O-CB 3.23Å; F426-L430 WeakPolarHBondContact O-CB 3.46Å; F426-L430 PolarHBondContact O-N 3.17Å
427	I	97.1	Very high	94.6	Very high	14 Å²	14	58.5 Å²	58.5	7%	0.072	29%	0.293	C	S	.	.	H	α-helix	trans	-63.2	-59.6	179.4	-66	-171.4	0	0	0	111.1	F92 L95 V423 P424 L425 A429 F431	F92-I427 HydrophobicContact CB-CG2 3.67Å; F92-I427 HydrophobicContact CD1-CD1 4.36Å; F92-I427 HydrophobicContact CD1-CG1 4.24Å; F92-I427 HydrophobicContact CD1-CG2 3.94Å; F92-I427 HydrophobicContact CE1-CD1 4.5Å; F92-I427 HydrophobicContact CE1-CG1 4.41Å; F92-I427 HydrophobicContact CG-CG2 3.95Å; F92-I427 WeakPolarHBondContact O-CG2 3.45Å; L95-I427 HydrophobicContact CB-CG2 4.35Å; L95-I427 HydrophobicContact CD1-CD1 4.19Å; V423-I427 HydrophobicContact CB-CD1 4.3Å; P424-I427 WeakPolarHBondContact O-CB 3.34Å; P424-I427 PolarHBondContact O-N 3.34Å; P424-I427 VanDerWaalsContact O-N 3.1Å; L425-I427 PolarHBondContact O-N 2.91Å; I427-A429 VanDerWaalsContact C-N 3.29Å; I427-A429 PolarHBondContact O-N 3.44Å; I427-F431 WeakPolarHBondContact O-CB 3.39Å; I427-F431 PolarHBondContact O-N 3.41Å; I427-F431 VanDerWaalsContact O-N 3.09Å
428	P	96.9	Very high	94.5	Very high	1 Å²	1	56 Å²	56	1%	0.006	28%	0.281	C	S	.	.	H	α-helix	trans	-65.9	-31.3	177.2	25.5	-33.7	0	0	0	112.4	S96 V404 L407 I408 P424 L425 S432	S96-P428 WeakPolarHBondContact OG-CA 3.44Å; V404-P428 HydrophobicContact CG1-CB 3.49Å; V404-P428 VanDerWaalsContact CG1-CB 3.49Å; V404-P428 WeakPolarHBondContact CG1-O 3.49Å; L407-P428 HydrophobicContact CD2-CB 4.12Å; L407-P428 HydrophobicContact CD2-CG 4.34Å; I408-P428 HydrophobicContact CD1-CB 4.21Å; I408-P428 HydrophobicContact CG1-CB 3.9Å; I408-P428 HydrophobicContact CG1-CG 4.08Å; P424-P428 WeakPolarHBondContact O-CD 3.46Å; L425-P428 VanDerWaalsContact O-CD 3.28Å; L425-P428 WeakPolarHBondContact O-CD 3.35Å; L425-P428 WeakPolarHBondContact O-CG 3.34Å; P428-S432 WeakPolarHBondContact O-CB 3.24Å; P428-S432 PolarHBondContact O-N 3.47Å
429	A	96.5	Very high	94.4	Very high	48 Å²	48	50.3 Å²	50.3	40%	0.397	26%	0.256	S	S	.	.	H	α-helix	trans	-64.6	-49.8	177.5	0	0	0	0	0	112.1	I408 L425 I427 F431 S432 F433	I408-A429 HydrophobicContact CD1-CB 4.28Å; L425-A429 VanDerWaalsContact O-CB 3.28Å; L425-A429 WeakPolarHBondContact O-CB 3.49Å; L425-A429 PolarHBondContact O-N 2.9Å; L425-A429 VanDerWaalsContact O-N 3.15Å; I427-A429 VanDerWaalsContact C-N 3.29Å; I427-A429 PolarHBondContact O-N 3.44Å; A429-F431 VanDerWaalsContact C-N 3.35Å; A429-F431 PolarHBondContact O-N 2.9Å; A429-S432 PolarHBondContact O-N 3.37Å; A429-F433 PolarHBondContact O-N 2.9Å
430	L	96.6	Very high	94.1	Very high	73 Å²	73	51.3 Å²	51.3	38%	0.382	27%	0.272	S	S	.	.	H	α-helix	trans	-65.3	-38.9	178.9	-178.8	59.4	0	0	0	111.9	L89 F92 F426 F433 T434	L89-L430 HydrophobicContact CD2-CG 4.38Å; F92-L430 HydrophobicContact CD2-CD2 3.86Å; F92-L430 HydrophobicContact CD2-CG 4.4Å; F92-L430 HydrophobicContact CE2-CD2 3.55Å; F426-L430 VanDerWaalsContact O-CB 3.23Å; F426-L430 WeakPolarHBondContact O-CB 3.46Å; F426-L430 PolarHBondContact O-N 3.17Å; L430-F433 PolarHBondContact O-N 2.89Å; L430-T434 PolarHBondContact O-N 3.45Å; L430-T434 PolarHBondContact O-OG1 3.27Å
431	F	96.3	Very high	93.7	Very high	0 Å²	0	49.4 Å²	49.4	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-70	-37.9	176	-176.5	-103.5	0	0	0	112.6	L89 F92 G93 M243 W249 W397 I400 V404 I427 A429 F433 T434 C435	L89-F431 WeakPolarHBondContact O-CD2 3.28Å; F92-F431 HydrophobicContact CB-CB 4.09Å; G93-F431 VanDerWaalsContact CA-CD1 3.44Å; G93-F431 VanDerWaalsContact CA-CE1 3.48Å; G93-F431 VanDerWaalsContact CA-CG 3.46Å; M243-F431 HydrophobicContact CE-CE2 4.29Å; W249-F431 HydrophobicContact CH2-CE1 4.24Å; W249-F431 HydrophobicContact CH2-CZ 4.12Å; W249-F431 HydrophobicContact CZ2-CE1 4.21Å; W249-F431 HydrophobicContact CZ2-CE2 4.31Å; W249-F431 AromaticContact CZ2-CZ 3.63Å; W249-F431 HydrophobicContact CZ2-CZ 3.63Å; W397-F431 HydrophobicContact CZ3-CE2 4.32Å; W397-F431 HydrophobicContact CZ3-CZ 4.03Å; I400-F431 HydrophobicContact CG2-CE1 3.57Å; I400-F431 HydrophobicContact CG2-CZ 3.82Å; V404-F431 HydrophobicContact CB-CD1 4.26Å; V404-F431 HydrophobicContact CG1-CD1 4.16Å; V404-F431 HydrophobicContact CG2-CD1 3.8Å; V404-F431 HydrophobicContact CG2-CE1 3.89Å; I427-F431 WeakPolarHBondContact O-CB 3.39Å; I427-F431 PolarHBondContact O-N 3.41Å; I427-F431 VanDerWaalsContact O-N 3.09Å; A429-F431 VanDerWaalsContact C-N 3.35Å; A429-F431 PolarHBondContact O-N 2.9Å; F431-F433 VanDerWaalsContact C-N 3.35Å; F431-T434 WeakPolarHBondContact O-CB 3.28Å; F431-T434 PolarHBondContact O-N 2.87Å; F431-C435 WeakPolarHBondContact CE1-SG 3.4Å; F431-C435 PolarHBondContact O-N 3.03Å; F431-C435 PolarHBondContact O-SG 3.46Å
432	S	95.6	Very high	93.1	Very high	15 Å²	15	47.1 Å²	47.1	11%	0.105	25%	0.249	C	C	.	.	H	α-helix	trans	-62.6	-42.7	173.7	-172	0	0	0	0	111.1	P428 A429 T434 C435 L436	P428-S432 WeakPolarHBondContact O-CB 3.24Å; P428-S432 PolarHBondContact O-N 3.47Å; A429-S432 PolarHBondContact O-N 3.37Å; S432-T434 VanDerWaalsContact C-N 3.33Å; S432-T434 PolarHBondContact O-N 3.25Å; S432-C435 WeakPolarHBondContact O-CB 3.29Å; S432-C435 PolarHBondContact O-N 3.41Å; S432-L436 WeakPolarHBondContact O-CG 3.3Å; S432-L436 PolarHBondContact O-N 3.48Å
433	F	94.4	Very high	92.6	Very high	131 Å²	131	43.9 Å²	43.9	58%	0.575	24%	0.239	S	C	*	.	H	α-helix	trans	-57.8	-44.6	170.8	175.3	-97.8	0	0	0	112	A429 L430 F431 C435 L436 F437	A429-F433 PolarHBondContact O-N 2.9Å; L430-F433 PolarHBondContact O-N 2.89Å; F431-F433 VanDerWaalsContact C-N 3.35Å; F433-C435 VanDerWaalsContact C-N 3.32Å; F433-C435 PolarHBondContact O-N 3.31Å; F433-L436 PolarHBondContact O-N 3.46Å; F433-F437 WeakPolarHBondContact O-CB 3.37Å; F433-F437 PolarHBondContact O-N 3.44Å
434	T	93.3	Very high	91.9	Very high	11 Å²	11	51.6 Å²	51.6	7%	0.067	27%	0.268	C	S	.	.	H	α-helix	trans	-58.9	-43.4	175.9	-55.6	0	0	0	0	111.2	L89 M243 L430 F431 S432 L436 F437 M438	L89-T434 HydrophobicContact CB-CG2 4.49Å; L89-T434 HydrophobicContact CD1-CG2 3.86Å; M243-T434 HydrophobicContact CE-CG2 4.32Å; L430-T434 PolarHBondContact O-N 3.45Å; L430-T434 PolarHBondContact O-OG1 3.27Å; F431-T434 WeakPolarHBondContact O-CB 3.28Å; F431-T434 PolarHBondContact O-N 2.87Å; S432-T434 VanDerWaalsContact C-N 3.33Å; S432-T434 PolarHBondContact O-N 3.25Å; T434-L436 PolarHBondContact O-N 2.95Å; T434-F437 WeakPolarHBondContact O-CB 3.33Å; T434-F437 PolarHBondContact O-N 2.78Å; T434-M438 HydrophobicContact CG2-CG 4.49Å; T434-M438 WeakPolarHBondContact O-CB 3.21Å; T434-M438 VanDerWaalsContact O-CG 3.25Å; T434-M438 WeakPolarHBondContact O-CG 3.36Å; T434-M438 PolarHBondContact O-N 3.12Å
435	C	93.9	Very high	91	Very high	1 Å²	1	50.2 Å²	50.2	1%	0.007	26%	0.26	C	S	.	.	H	α-helix	trans	-62.5	-43.3	177	-65.3	0	0	0	0	112.1	F431 S432 F433 M438 V439	F431-C435 WeakPolarHBondContact CE1-SG 3.4Å; F431-C435 PolarHBondContact O-N 3.03Å; F431-C435 PolarHBondContact O-SG 3.46Å; S432-C435 WeakPolarHBondContact O-CB 3.29Å; S432-C435 PolarHBondContact O-N 3.41Å; F433-C435 VanDerWaalsContact C-N 3.32Å; F433-C435 PolarHBondContact O-N 3.31Å; C435-M438 WeakPolarHBondContact O-CB 3.04Å; C435-M438 PolarHBondContact O-N 2.76Å; C435-V439 VanDerWaalsContact O-CG2 3.32Å; C435-V439 WeakPolarHBondContact O-CG2 3.14Å; C435-V439 PolarHBondContact O-N 3.18Å
436	L	91.9	Very high	90.2	Very high	104 Å²	104	48.2 Å²	48.2	55%	0.545	25%	0.25	S	C	.	.	H	α-helix	trans	-64.5	-41.1	176.5	-68.6	175.2	0	0	0	111.9	S432 F433 T434 M438 V439 A440	S432-L436 WeakPolarHBondContact O-CG 3.3Å; S432-L436 PolarHBondContact O-N 3.48Å; F433-L436 PolarHBondContact O-N 3.46Å; T434-L436 PolarHBondContact O-N 2.95Å; L436-M438 VanDerWaalsContact C-N 3.34Å; L436-M438 PolarHBondContact O-N 3.17Å; L436-V439 PolarHBondContact O-N 2.9Å; L436-A440 PolarHBondContact O-N 3.39Å
437	F	90.2	Very high	89.7	Confident	80 Å²	80	46.3 Å²	46.3	35%	0.351	25%	0.25	S	C	.	.	H	α-helix	trans	-59.8	-44.9	173.7	176	-104.9	0	0	0	111.5	P236 F433 T434 V439 A440 L441	P236-F437 HydrophobicContact CB-CE1 4.25Å; P236-F437 HydrophobicContact CB-CZ 3.81Å; P236-F437 HydrophobicContact CG-CZ 3.86Å; F433-F437 WeakPolarHBondContact O-CB 3.37Å; F433-F437 PolarHBondContact O-N 3.44Å; T434-F437 WeakPolarHBondContact O-CB 3.33Å; T434-F437 PolarHBondContact O-N 2.78Å; F437-V439 VanDerWaalsContact C-N 3.34Å; F437-V439 PolarHBondContact O-N 3.02Å; F437-A440 PolarHBondContact O-N 3.24Å; F437-L441 WeakPolarHBondContact O-CB 3.49Å; F437-L441 PolarHBondContact O-N 3.4Å
438	M	89.8	Confident	89.2	Confident	1 Å²	1	53.2 Å²	53.2	1%	0.005	28%	0.28	C	S	.	.	H	α-helix	trans	-61.8	-39.8	175.6	-73.5	-53.7	-64.4	0	0	112.8	F239 Y240 M243 W397 T434 C435 L436 L441 S442	F239-M438 HydrophobicContact CB-SD 4.42Å; Y240-M438 VanDerWaalsContact CA-CE 3.45Å; Y240-M438 HydrophobicContact CD2-CE 3.66Å; Y240-M438 HydrophobicContact CG-CE 4.14Å; M243-M438 HydrophobicContact CB-CE 4.42Å; M243-M438 HydrophobicContact CG-SD 4.41Å; W397-M438 HydrophobicContact CB-CB 4.06Å; W397-M438 HydrophobicContact CD2-CB 4.06Å; W397-M438 HydrophobicContact CD2-CG 4.19Å; W397-M438 HydrophobicContact CG-CB 3.7Å; W397-M438 HydrophobicContact CG-CG 4.34Å; T434-M438 HydrophobicContact CG2-CG 4.49Å; T434-M438 WeakPolarHBondContact O-CB 3.21Å; T434-M438 VanDerWaalsContact O-CG 3.25Å; T434-M438 WeakPolarHBondContact O-CG 3.36Å; T434-M438 PolarHBondContact O-N 3.12Å; C435-M438 WeakPolarHBondContact O-CB 3.04Å; C435-M438 PolarHBondContact O-N 2.76Å; L436-M438 VanDerWaalsContact C-N 3.34Å; L436-M438 PolarHBondContact O-N 3.17Å; M438-L441 PolarHBondContact O-N 3.1Å; M438-S442 PolarHBondContact O-N 3.21Å; M438-S442 PolarHBondContact O-OG 3.36Å; M438-S442 VanDerWaalsContact O-OG 3.08Å
439	V	89.8	Confident	88.5	Confident	16 Å²	16	54 Å²	54	10%	0.097	29%	0.285	C	S	.	.	H	α-helix	trans	-63.9	-48.1	175.5	167	0	0	0	0	111.2	F394 W397 L398 C435 L436 F437 L441 S442 L443	F394-V439 HydrophobicContact CD2-CG1 3.8Å; F394-V439 HydrophobicContact CE2-CG1 3.55Å; W397-V439 HydrophobicContact CB-CG2 3.89Å; L398-V439 HydrophobicContact CB-CG2 3.97Å; C435-V439 VanDerWaalsContact O-CG2 3.32Å; C435-V439 WeakPolarHBondContact O-CG2 3.14Å; C435-V439 PolarHBondContact O-N 3.18Å; L436-V439 PolarHBondContact O-N 2.9Å; F437-V439 VanDerWaalsContact C-N 3.34Å; F437-V439 PolarHBondContact O-N 3.02Å; V439-L441 VanDerWaalsContact C-N 3.26Å; V439-L441 PolarHBondContact O-N 3.46Å; V439-S442 PolarHBondContact O-N 2.65Å; V439-L443 PolarHBondContact O-N 2.98Å
440	A	87.4	Confident	87.9	Confident	57 Å²	57	51.7 Å²	51.7	47%	0.471	27%	0.266	S	S	.	.	H	α-helix	trans	-61	-38.9	177.3	0	0	0	0	0	111.5	L436 F437 L443 Y444	L436-A440 PolarHBondContact O-N 3.39Å; F437-A440 PolarHBondContact O-N 3.24Å; A440-L443 WeakPolarHBondContact O-CB 3.37Å; A440-L443 PolarHBondContact O-N 3.48Å; A440-Y444 PolarHBondContact O-N 3.25Å; A440-Y444 VanDerWaalsContact O-N 3.09Å
441	L	82.9	Confident	87.4	Confident	9 Å²	9	49.3 Å²	49.3	5%	0.047	26%	0.259	C	S	.	.	H	α-helix	trans	-64.5	-46.8	175.4	175.9	61.5	0	0	0	112.4	P236 F437 M438 V439 L443 Y444 S445	P236-L441 HydrophobicContact CB-CB 4.44Å; P236-L441 HydrophobicContact CB-CD1 3.27Å; P236-L441 HydrophobicContact CB-CD2 3.49Å; P236-L441 VanDerWaalsContact CB-CD2 3.49Å; P236-L441 HydrophobicContact CB-CG 3.86Å; P236-L441 HydrophobicContact CG-CD1 4.31Å; P236-L441 WeakPolarHBondContact O-CD2 3.25Å; F437-L441 WeakPolarHBondContact O-CB 3.49Å; F437-L441 PolarHBondContact O-N 3.4Å; M438-L441 PolarHBondContact O-N 3.1Å; V439-L441 VanDerWaalsContact C-N 3.26Å; V439-L441 PolarHBondContact O-N 3.46Å; L441-L443 PolarHBondContact O-N 3.24Å; L441-Y444 HydrophobicContact CD1-CD1 4.37Å; L441-Y444 PolarHBondContact O-N 2.93Å; L441-S445 VanDerWaalsContact CD1-OG 3.29Å; L441-S445 WeakPolarHBondContact CD1-OG 3.12Å; L441-S445 WeakPolarHBondContact O-CB 3.15Å; L441-S445 PolarHBondContact O-N 2.86Å; L441-S445 PolarHBondContact O-OG 3.03Å; L441-S445 VanDerWaalsContact O-OG 3.12Å
442	S	82.7	Confident	86.9	Confident	3 Å²	3	52.5 Å²	52.5	2%	0.021	28%	0.276	C	S	.	.	H	α-helix	trans	-55.9	-40.8	178.4	-60.8	0	0	0	0	111.2	M438 V439 Y444 D446 T450	M438-S442 PolarHBondContact O-N 3.21Å; M438-S442 PolarHBondContact O-OG 3.36Å; M438-S442 VanDerWaalsContact O-OG 3.08Å; V439-S442 PolarHBondContact O-N 2.65Å; S442-Y444 PolarHBondContact O-N 3.15Å; S442-D446 PolarHBondContact O-N 3.32Å; S442-D446 VanDerWaalsContact O-N 3.15Å; S442-T450 PolarHBondContact O-OG1 2.97Å
443	L	83.6	Confident	86.4	Confident	80 Å²	80	51.8 Å²	51.8	42%	0.419	27%	0.271	S	S	.	.	H	α-helix	trans	-62.9	-38.7	174.5	-75.2	164.7	0	0	0	113.2	F394 V439 A440 L441 P447 T450	F394-L443 HydrophobicContact CD2-CG 4.32Å; F394-L443 HydrophobicContact CE2-CD1 4.23Å; F394-L443 HydrophobicContact CE2-CD2 4.44Å; F394-L443 HydrophobicContact CE2-CG 4.22Å; V439-L443 PolarHBondContact O-N 2.98Å; A440-L443 WeakPolarHBondContact O-CB 3.37Å; A440-L443 PolarHBondContact O-N 3.48Å; L441-L443 PolarHBondContact O-N 3.24Å; L443-P447 WeakPolarHBondContact O-CA 3.27Å; L443-P447 WeakPolarHBondContact O-CB 3.45Å; L443-P447 VanDerWaalsContact O-CG 3.26Å; L443-P447 WeakPolarHBondContact O-CG 3.26Å; L443-T450 HydrophobicContact CB-CG2 4.49Å; L443-T450 HydrophobicContact CD2-CG2 3.48Å; L443-T450 VanDerWaalsContact CD2-CG2 3.48Å; L443-T450 HydrophobicContact CG-CG2 3.78Å
444	Y	82.3	Confident	86.1	Confident	169 Å²	169	49.9 Å²	49.9	66%	0.663	26%	0.262	S	S	*	.	H	α-helix	trans	-73.2	-42.2	178.2	174.8	-100.2	0	0	0	112.6	A440 L441 S442	A440-Y444 PolarHBondContact O-N 3.25Å; A440-Y444 VanDerWaalsContact O-N 3.09Å; L441-Y444 HydrophobicContact CD1-CD1 4.37Å; L441-Y444 PolarHBondContact O-N 2.93Å; S442-Y444 PolarHBondContact O-N 3.15Å
445	S	77.5	Confident	85.9	Confident	42 Å²	42	54.4 Å²	54.4	29%	0.294	29%	0.285	S	S	.	.	H	α-helix	trans	-73.1	-43.3	-173.1	-63.3	0	0	0	0	113.3	L237 L441	L237-S445 WeakPolarHBondContact CD2-OG 3.35Å; L441-S445 VanDerWaalsContact CD1-OG 3.29Å; L441-S445 WeakPolarHBondContact CD1-OG 3.12Å; L441-S445 WeakPolarHBondContact O-CB 3.15Å; L441-S445 PolarHBondContact O-N 2.86Å; L441-S445 PolarHBondContact O-OG 3.03Å; L441-S445 VanDerWaalsContact O-OG 3.12Å
446	D	79.4	Confident	85.7	Confident	32 Å²	32	56.4 Å²	56.4	17%	0.171	30%	0.295	C	S	.	.			trans	-143.4	82.7	177.1	-174.7	-7.9	0	0	0	109.4	N390 S442 F448 S449 T450	N390-D446 HydrophobicContact CB-CB 4.28Å; S442-D446 PolarHBondContact O-N 3.32Å; S442-D446 VanDerWaalsContact O-N 3.15Å; D446-F448 PolarHBondContact O-N 3.49Å; D446-F448 PolarHBondContact OD1-N 3.24Å; D446-S449 VanDerWaalsContact CG-CB 3.49Å; D446-S449 VanDerWaalsContact CG-OG 3.29Å; D446-S449 PolarHBondContact OD1-N 3.11Å; D446-S449 PolarHBondContact OD1-OG 2.67Å; D446-S449 WeakPolarHBondContact OD2-CB 3.16Å; D446-S449 PolarHBondContact OD2-OG 3.31Å; D446-T450 WeakPolarHBondContact O-CB 3.31Å; D446-T450 PolarHBondContact O-N 3.43Å; D446-T450 PolarHBondContact O-OG1 3.25Å
447	P	85.9	Confident	85.7	Confident	85 Å²	85	52 Å²	52	55%	0.552	27%	0.272	S	S	*	.	H	α-helix	trans	-61.2	-30.3	-178.3	-18.3	26.6	0	0	0	112.8	L443 G451	L443-P447 WeakPolarHBondContact O-CA 3.27Å; L443-P447 WeakPolarHBondContact O-CB 3.45Å; L443-P447 VanDerWaalsContact O-CG 3.26Å; L443-P447 WeakPolarHBondContact O-CG 3.26Å; P447-G451 WeakPolarHBondContact O-CA 3.39Å; P447-G451 PolarHBondContact O-N 3.48Å
448	F	86.1	Confident	85.8	Confident	159 Å²	159	52.4 Å²	52.4	70%	0.697	28%	0.278	S	S	*	.	H	α-helix	trans	-73.9	-57.2	-176.1	-177.2	-100	0	0	0	110.9	D446 T450 G451 I452	D446-F448 PolarHBondContact O-N 3.49Å; D446-F448 PolarHBondContact OD1-N 3.24Å; F448-T450 VanDerWaalsContact C-N 3.29Å; F448-T450 PolarHBondContact O-N 2.98Å; F448-G451 PolarHBondContact O-N 3.1Å; F448-I452 HydrophobicContact CD1-CD1 3.92Å; F448-I452 HydrophobicContact CE1-CD1 3.48Å; F448-I452 VanDerWaalsContact CE1-CD1 3.48Å; F448-I452 HydrophobicContact CZ-CD1 3.83Å; F448-I452 WeakPolarHBondContact O-CG1 3.47Å; F448-I452 PolarHBondContact O-N 2.97Å
449	S	82.3	Confident	86.1	Confident	18 Å²	18	55 Å²	55	13%	0.126	29%	0.294	C	S	.	.	H	α-helix	trans	-62.1	-40.9	178.4	-56.2	0	0	0	0	110.9	F391 D446 I452 G453	F391-S449 WeakPolarHBondContact CD2-O 3.09Å; D446-S449 VanDerWaalsContact CG-CB 3.49Å; D446-S449 VanDerWaalsContact CG-OG 3.29Å; D446-S449 PolarHBondContact OD1-N 3.11Å; D446-S449 PolarHBondContact OD1-OG 2.67Å; D446-S449 WeakPolarHBondContact OD2-CB 3.16Å; D446-S449 PolarHBondContact OD2-OG 3.31Å; S449-I452 PolarHBondContact O-N 3Å; S449-G453 PolarHBondContact O-N 3.14Å
450	T	83.2	Confident	86.3	Confident	0 Å²	0	54.2 Å²	54.2	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-65.2	-40.3	176.7	-59.1	0	0	0	0	112	F394 S442 L443 D446 F448 I452 G453 F454	F394-T450 HydrophobicContact CB-CG2 3.65Å; F394-T450 HydrophobicContact CD1-CG2 4.3Å; F394-T450 HydrophobicContact CD2-CG2 3.38Å; F394-T450 HydrophobicContact CE2-CG2 4.1Å; F394-T450 HydrophobicContact CG-CG2 3.51Å; S442-T450 PolarHBondContact O-OG1 2.97Å; L443-T450 HydrophobicContact CB-CG2 4.49Å; L443-T450 HydrophobicContact CD2-CG2 3.48Å; L443-T450 VanDerWaalsContact CD2-CG2 3.48Å; L443-T450 HydrophobicContact CG-CG2 3.78Å; D446-T450 WeakPolarHBondContact O-CB 3.31Å; D446-T450 PolarHBondContact O-N 3.43Å; D446-T450 PolarHBondContact O-OG1 3.25Å; F448-T450 VanDerWaalsContact C-N 3.29Å; F448-T450 PolarHBondContact O-N 2.98Å; T450-I452 VanDerWaalsContact C-N 3.34Å; T450-I452 PolarHBondContact O-N 3.38Å; T450-G453 PolarHBondContact O-N 3.33Å; T450-G453 VanDerWaalsContact O-N 3.16Å; T450-F454 PolarHBondContact O-N 3.48Å
451	G	86.3	Confident	86.6	Confident	23 Å²	23	54 Å²	54	24%	0.237	28%	0.282	C	S	.	.	H	α-helix	trans	-59.6	-43	175.4	0	0	0	0	0	112.3	P447 F448 G453 F454 I455	P447-G451 WeakPolarHBondContact O-CA 3.39Å; P447-G451 PolarHBondContact O-N 3.48Å; F448-G451 PolarHBondContact O-N 3.1Å; G451-G453 PolarHBondContact O-N 3.35Å; G451-F454 PolarHBondContact O-N 3.33Å; G451-I455 VanDerWaalsContact O-CG1 3.31Å; G451-I455 WeakPolarHBondContact O-CG1 3.25Å; G451-I455 PolarHBondContact O-N 3.27Å
452	I	85.7	Confident	87.3	Confident	66 Å²	66	57.3 Å²	57.3	34%	0.338	30%	0.304	S	S	.	.	H	α-helix	trans	-61.4	-45.3	173.6	-62.7	168.3	0	0	0	110.4	F391 F448 S449 T450 F454 I455 I456	F391-I452 HydrophobicContact CE2-CB 4.27Å; F391-I452 HydrophobicContact CE2-CG2 3.9Å; F448-I452 HydrophobicContact CD1-CD1 3.92Å; F448-I452 HydrophobicContact CE1-CD1 3.48Å; F448-I452 VanDerWaalsContact CE1-CD1 3.48Å; F448-I452 HydrophobicContact CZ-CD1 3.83Å; F448-I452 WeakPolarHBondContact O-CG1 3.47Å; F448-I452 PolarHBondContact O-N 2.97Å; S449-I452 PolarHBondContact O-N 3Å; T450-I452 VanDerWaalsContact C-N 3.34Å; T450-I452 PolarHBondContact O-N 3.38Å; I452-F454 VanDerWaalsContact C-N 3.3Å; I452-F454 PolarHBondContact O-N 3.43Å; I452-I455 PolarHBondContact O-N 3.21Å; I452-I456 HydrophobicContact CG2-CD1 3.8Å; I452-I456 HydrophobicContact CG2-CG1 4.46Å; I452-I456 WeakPolarHBondContact O-CG1 3.45Å; I452-I456 PolarHBondContact O-N 3.4Å
453	G	85	Confident	87.8	Confident	0 Å²	0	57.7 Å²	57.7	0%	0	31%	0.307	C	S	.	.	H	α-helix	trans	-60.3	-38.8	177.3	0	0	0	0	0	112.9	S449 T450 G451 T457	S449-G453 PolarHBondContact O-N 3.14Å; T450-G453 PolarHBondContact O-N 3.33Å; T450-G453 VanDerWaalsContact O-N 3.16Å; G451-G453 PolarHBondContact O-N 3.35Å; G453-T457 WeakPolarHBondContact O-CB 3.4Å; G453-T457 PolarHBondContact O-N 2.85Å; G453-T457 PolarHBondContact O-OG1 3.47Å
454	F	88.3	Confident	88.3	Confident	92 Å²	92	55 Å²	55	40%	0.404	29%	0.292	S	S	.	.	H	α-helix	trans	-66.5	-45.3	173.9	-179.6	-109.1	0	0	0	112.3	F394 T450 G451 I452 I456 T457 L458	F394-F454 HydrophobicContact CE1-CB 3.93Å; F394-F454 AromaticContact CE1-CD2 3.92Å; F394-F454 HydrophobicContact CE1-CD2 3.92Å; F394-F454 HydrophobicContact CE1-CG 4.43Å; F394-F454 HydrophobicContact CZ-CB 4.13Å; F394-F454 AromaticContact CZ-CD2 3.67Å; F394-F454 HydrophobicContact CZ-CD2 3.67Å; F394-F454 HydrophobicContact CZ-CG 4.32Å; T450-F454 PolarHBondContact O-N 3.48Å; G451-F454 PolarHBondContact O-N 3.33Å; I452-F454 VanDerWaalsContact C-N 3.3Å; I452-F454 PolarHBondContact O-N 3.43Å; F454-I456 VanDerWaalsContact C-N 3.35Å; F454-I456 PolarHBondContact O-N 2.93Å; F454-T457 CarbonylContact O-C 3.54Å; F454-T457 WeakPolarHBondContact O-CA 3.43Å; F454-T457 VanDerWaalsContact O-CB 3.28Å; F454-T457 WeakPolarHBondContact O-CB 3.3Å; F454-T457 PolarHBondContact O-N 3.39Å; F454-T457 VanDerWaalsContact O-N 3.1Å; F454-L458 HydrophobicContact CD1-CD1 4.01Å; F454-L458 HydrophobicContact CD1-CG 4.44Å; F454-L458 HydrophobicContact CE1-CD1 3.44Å; F454-L458 VanDerWaalsContact CE1-CD1 3.44Å; F454-L458 HydrophobicContact CE1-CG 4.06Å; F454-L458 HydrophobicContact CE2-CD2 4.46Å; F454-L458 HydrophobicContact CE2-CG 4.41Å; F454-L458 HydrophobicContact CZ-CD1 3.8Å; F454-L458 HydrophobicContact CZ-CD2 4.15Å; F454-L458 HydrophobicContact CZ-CG 4.05Å; F454-L458 PolarHBondContact O-N 3.16Å
455	I	90.5	Very high	88.8	Confident	105 Å²	105	52.9 Å²	52.9	54%	0.538	28%	0.283	S	S	.	.	H	α-helix	trans	-59.1	-47	176.8	-70.5	165.4	0	0	0	110.5	G451 I452 T457 L458 T459	G451-I455 VanDerWaalsContact O-CG1 3.31Å; G451-I455 WeakPolarHBondContact O-CG1 3.25Å; G451-I455 PolarHBondContact O-N 3.27Å; I452-I455 PolarHBondContact O-N 3.21Å; I455-T457 VanDerWaalsContact C-N 3.26Å; I455-T457 PolarHBondContact O-N 2.88Å; I455-L458 CarbonylContact O-C 3.6Å; I455-L458 WeakPolarHBondContact O-CA 3.35Å; I455-L458 WeakPolarHBondContact O-CB 3.45Å; I455-L458 PolarHBondContact O-N 2.63Å; I455-T459 WeakPolarHBondContact O-CG2 3.25Å; I455-T459 PolarHBondContact O-N 3.27Å
456	I	88.6	Confident	89.4	Confident	44 Å²	44	55 Å²	55	23%	0.226	29%	0.291	C	S	.	.	H	α-helix	trans	-64.3	-35.5	177.8	-62.9	164	0	0	0	110.5	I133 F391 I452 F454 L458 T459	I133-I456 HydrophobicContact CD1-CB 3.47Å; I133-I456 VanDerWaalsContact CD1-CB 3.47Å; I133-I456 HydrophobicContact CD1-CD1 3.81Å; I133-I456 HydrophobicContact CD1-CG1 4.24Å; I133-I456 HydrophobicContact CD1-CG2 3.24Å; I133-I456 HydrophobicContact CG1-CD1 4.3Å; I133-I456 HydrophobicContact CG1-CG2 3.93Å; F391-I456 HydrophobicContact CE2-CD1 4.1Å; F391-I456 HydrophobicContact CZ-CD1 3.72Å; I452-I456 HydrophobicContact CG2-CD1 3.8Å; I452-I456 HydrophobicContact CG2-CG1 4.46Å; I452-I456 WeakPolarHBondContact O-CG1 3.45Å; I452-I456 PolarHBondContact O-N 3.4Å; F454-I456 VanDerWaalsContact C-N 3.35Å; F454-I456 PolarHBondContact O-N 2.93Å; I456-L458 VanDerWaalsContact C-N 3.32Å; I456-L458 PolarHBondContact O-N 2.86Å; I456-T459 PolarHBondContact O-N 3.28Å; I456-T459 VanDerWaalsContact O-N 3.14Å; I456-T459 PolarHBondContact O-OG1 3.02Å
457	T	91.8	Very high	89.8	Confident	10 Å²	10	57.4 Å²	57.4	6%	0.061	30%	0.3	C	S	.	.	H	α-helix	trans	-58.8	-44.8	171.2	-58.8	0	0	0	0	111.5	V125 V129 F399 G453 F454 I455 T459 G460	V125-T457 HydrophobicContact CG1-CG2 3.88Å; V125-T457 VanDerWaalsContact CG1-O 3.29Å; V125-T457 WeakPolarHBondContact CG1-O 3.36Å; V129-T457 VanDerWaalsContact CG2-CA 3.48Å; V129-T457 HydrophobicContact CG2-CG2 3.96Å; F399-T457 HydrophobicContact CE2-CG2 4.27Å; F399-T457 HydrophobicContact CZ-CG2 4.13Å; G453-T457 WeakPolarHBondContact O-CB 3.4Å; G453-T457 PolarHBondContact O-N 2.85Å; G453-T457 PolarHBondContact O-OG1 3.47Å; F454-T457 CarbonylContact O-C 3.54Å; F454-T457 WeakPolarHBondContact O-CA 3.43Å; F454-T457 VanDerWaalsContact O-CB 3.28Å; F454-T457 WeakPolarHBondContact O-CB 3.3Å; F454-T457 PolarHBondContact O-N 3.39Å; F454-T457 VanDerWaalsContact O-N 3.1Å; I455-T457 VanDerWaalsContact C-N 3.26Å; I455-T457 PolarHBondContact O-N 2.88Å; T457-T459 VanDerWaalsContact C-N 3.3Å; T457-T459 PolarHBondContact O-N 3.43Å; T457-G460 PolarHBondContact O-N 3.44Å; T457-G460 VanDerWaalsContact O-N 3.14Å
458	L	93	Very high	90	Very high	89 Å²	89	55.7 Å²	55.7	47%	0.466	29%	0.286	S	S	.	.	H	α-helix	trans	-64.5	-31.5	175.4	-68.4	179.6	0	0	0	113	F454 I455 I456 G460 V461 P462	F454-L458 HydrophobicContact CD1-CD1 4.01Å; F454-L458 HydrophobicContact CD1-CG 4.44Å; F454-L458 HydrophobicContact CE1-CD1 3.44Å; F454-L458 VanDerWaalsContact CE1-CD1 3.44Å; F454-L458 HydrophobicContact CE1-CG 4.06Å; F454-L458 HydrophobicContact CE2-CD2 4.46Å; F454-L458 HydrophobicContact CE2-CG 4.41Å; F454-L458 HydrophobicContact CZ-CD1 3.8Å; F454-L458 HydrophobicContact CZ-CD2 4.15Å; F454-L458 HydrophobicContact CZ-CG 4.05Å; F454-L458 PolarHBondContact O-N 3.16Å; I455-L458 CarbonylContact O-C 3.6Å; I455-L458 WeakPolarHBondContact O-CA 3.35Å; I455-L458 WeakPolarHBondContact O-CB 3.45Å; I455-L458 PolarHBondContact O-N 2.63Å; I456-L458 VanDerWaalsContact C-N 3.32Å; I456-L458 PolarHBondContact O-N 2.86Å; L458-G460 PolarHBondContact O-N 2.68Å; L458-G460 VanDerWaalsContact O-N 3.14Å; L458-V461 WeakPolarHBondContact O-CB 3.38Å; L458-V461 PolarHBondContact O-N 2.96Å; L458-P462 WeakPolarHBondContact O-CD 3.5Å
459	T	95.2	Very high	90.1	Very high	56 Å²	56	51.8 Å²	51.8	34%	0.344	27%	0.271	S	S	.	.	H	α-helix	trans	-62.8	-18.7	175.2	70.1	0	0	0	0	113.6	W128 I455 I456 T457 V461 P462 A463	W128-T459 PolarHBondContact NE1-OG1 3.13Å; I455-T459 WeakPolarHBondContact O-CG2 3.25Å; I455-T459 PolarHBondContact O-N 3.27Å; I456-T459 PolarHBondContact O-N 3.28Å; I456-T459 VanDerWaalsContact O-N 3.14Å; I456-T459 PolarHBondContact O-OG1 3.02Å; T457-T459 VanDerWaalsContact C-N 3.3Å; T457-T459 PolarHBondContact O-N 3.43Å; T459-V461 PolarHBondContact O-N 3.24Å; T459-P462 VanDerWaalsContact O-CD 3.25Å; T459-P462 WeakPolarHBondContact O-CD 3.36Å; T459-P462 WeakPolarHBondContact O-CG 3.39Å; T459-A463 VanDerWaalsContact O-CB 3.26Å; T459-A463 WeakPolarHBondContact O-CB 3.19Å; T459-A463 PolarHBondContact O-N 3.33Å; T459-A463 VanDerWaalsContact O-N 3.16Å
460	G	94.3	Very high	90.4	Very high	0 Å²	0	56.6 Å²	56.6	0%	0	29%	0.287	C	S	.	.	H	α-helix	trans	-62.3	-27.9	171.1	0	0	0	0	0	113.3	F124 T457 L458 Y464	F124-G460 WeakPolarHBondContact CD1-O 3.47Å; F124-G460 VanDerWaalsContact CE1-O 3.25Å; F124-G460 WeakPolarHBondContact CE1-O 3.13Å; T457-G460 PolarHBondContact O-N 3.44Å; T457-G460 VanDerWaalsContact O-N 3.14Å; L458-G460 PolarHBondContact O-N 2.68Å; L458-G460 VanDerWaalsContact O-N 3.14Å; G460-Y464 WeakPolarHBondContact O-CB 3.36Å; G460-Y464 PolarHBondContact O-N 3.26Å
461	V	95.3	Very high	90.1	Very high	52 Å²	52	63.6 Å²	63.6	32%	0.315	32%	0.324	S	S	.	.	H	α-helix	trans	-69.3	-57.4	179	-178.6	0	0	0	0	112	L121 V125 L458 T459 A463 Y464 Y465	L121-V461 HydrophobicContact CD1-CG1 4.34Å; V125-V461 HydrophobicContact CG2-CG2 4.02Å; L458-V461 WeakPolarHBondContact O-CB 3.38Å; L458-V461 PolarHBondContact O-N 2.96Å; T459-V461 PolarHBondContact O-N 3.24Å; V461-A463 VanDerWaalsContact C-N 3.25Å; V461-A463 PolarHBondContact O-N 2.83Å; V461-Y464 WeakPolarHBondContact O-CB 3.37Å; V461-Y464 PolarHBondContact O-N 3.33Å; V461-Y464 VanDerWaalsContact O-N 3.11Å; V461-Y465 HydrophobicContact CG1-CD2 4.15Å; V461-Y465 HydrophobicContact CG1-CE2 3.9Å; V461-Y465 VanDerWaalsContact O-CD2 3.28Å; V461-Y465 WeakPolarHBondContact O-CD2 3.38Å; V461-Y465 PolarHBondContact O-N 3.01Å
462	P	95.6	Very high	89.9	Confident	79 Å²	79	71.1 Å²	71.1	51%	0.513	35%	0.35	S	S	.	.	H	α-helix	trans	-62.3	-34.8	175.9	24.9	-33	0	0	0	111.8	L458 T459 Y464 Y465 L466	L458-P462 WeakPolarHBondContact O-CD 3.5Å; T459-P462 VanDerWaalsContact O-CD 3.25Å; T459-P462 WeakPolarHBondContact O-CD 3.36Å; T459-P462 WeakPolarHBondContact O-CG 3.39Å; P462-Y464 VanDerWaalsContact C-N 3.32Å; P462-Y464 PolarHBondContact O-N 3.42Å; P462-Y465 PolarHBondContact O-N 3.16Å; P462-L466 VanDerWaalsContact O-CB 3.31Å; P462-L466 WeakPolarHBondContact O-CB 3.44Å; P462-L466 PolarHBondContact O-N 3.34Å
463	A	94.1	Very high	89.8	Confident	10 Å²	10	71 Å²	71	8%	0.083	35%	0.347	C	S	.	.	H	α-helix	trans	-60.4	-40.1	173.5	0	0	0	0	0	112.1	F124 W128 T459 V461 L466 F467	F124-A463 HydrophobicContact CE1-CB 3.93Å; F124-A463 HydrophobicContact CZ-CB 4.2Å; W128-A463 HydrophobicContact CD2-CB 4.1Å; W128-A463 HydrophobicContact CE3-CB 4.11Å; W128-A463 HydrophobicContact CH2-CB 3.78Å; W128-A463 HydrophobicContact CZ2-CB 3.74Å; W128-A463 HydrophobicContact CZ3-CB 3.96Å; T459-A463 VanDerWaalsContact O-CB 3.26Å; T459-A463 WeakPolarHBondContact O-CB 3.19Å; T459-A463 PolarHBondContact O-N 3.33Å; T459-A463 VanDerWaalsContact O-N 3.16Å; V461-A463 VanDerWaalsContact C-N 3.25Å; V461-A463 PolarHBondContact O-N 2.83Å; A463-L466 PolarHBondContact O-N 3.2Å; A463-F467 HydrophobicContact CB-CD2 4.07Å; A463-F467 HydrophobicContact CB-CE2 4.27Å; A463-F467 WeakPolarHBondContact O-CB 3.44Å; A463-F467 VanDerWaalsContact O-CD2 3.22Å; A463-F467 WeakPolarHBondContact O-CD2 3.36Å; A463-F467 PolarHBondContact O-N 2.93Å
464	Y	93.8	Very high	90	Very high	25 Å²	25	73 Å²	73	10%	0.098	36%	0.36	C	S	.	.	H	α-helix	trans	-61.1	-47.9	175.5	180	-109.4	0	0	0	112.1	P120 L121 F124 G460 V461 P462 L466 I468 I469	P120-Y464 HydrophobicContact CB-CE2 4.36Å; P120-Y464 VanDerWaalsContact CB-OH 3.26Å; P120-Y464 WeakPolarHBondContact CB-OH 3.39Å; L121-Y464 HydrophobicContact CB-CD1 3.98Å; L121-Y464 HydrophobicContact CB-CE1 3.74Å; L121-Y464 HydrophobicContact CD1-CD1 3.33Å; L121-Y464 HydrophobicContact CD1-CE1 4.02Å; L121-Y464 HydrophobicContact CD1-CG 3.64Å; L121-Y464 HydrophobicContact CG-CD1 4.22Å; L121-Y464 HydrophobicContact CG-CE1 4.45Å; F124-Y464 HydrophobicContact CB-CD2 3.39Å; F124-Y464 HydrophobicContact CB-CE2 3.93Å; F124-Y464 HydrophobicContact CB-CG 4.25Å; F124-Y464 AromaticContact CD1-CD2 3.86Å; F124-Y464 HydrophobicContact CD1-CD2 3.86Å; F124-Y464 HydrophobicContact CD1-CG 4.14Å; F124-Y464 AromaticContact CD2-CD2 3.83Å; F124-Y464 HydrophobicContact CD2-CD2 3.83Å; F124-Y464 AromaticContact CG-CD2 3.42Å; F124-Y464 HydrophobicContact CG-CD2 3.42Å; F124-Y464 VanDerWaalsContact CG-CD2 3.42Å; F124-Y464 HydrophobicContact CG-CE2 4.32Å; F124-Y464 HydrophobicContact CG-CG 4.16Å; G460-Y464 WeakPolarHBondContact O-CB 3.36Å; G460-Y464 PolarHBondContact O-N 3.26Å; V461-Y464 WeakPolarHBondContact O-CB 3.37Å; V461-Y464 PolarHBondContact O-N 3.33Å; V461-Y464 VanDerWaalsContact O-N 3.11Å; P462-Y464 VanDerWaalsContact C-N 3.32Å; P462-Y464 PolarHBondContact O-N 3.42Å; Y464-L466 VanDerWaalsContact C-N 3.32Å; Y464-L466 PolarHBondContact O-N 3.25Å; Y464-I468 HydrophobicContact CD2-CB 3.8Å; Y464-I468 HydrophobicContact CD2-CG1 3.6Å; Y464-I468 HydrophobicContact CD2-CG2 4.29Å; Y464-I468 HydrophobicContact CE2-CB 3.72Å; Y464-I468 HydrophobicContact CE2-CG1 3.84Å; Y464-I468 HydrophobicContact CE2-CG2 3.69Å; Y464-I468 WeakPolarHBondContact O-CA 3.16Å; Y464-I468 VanDerWaalsContact O-CB 3.26Å; Y464-I468 WeakPolarHBondContact O-CB 2.98Å; Y464-I468 PolarHBondContact O-N 2.81Å; Y464-I469 HydrophobicContact CD1-CD1 3.78Å; Y464-I469 HydrophobicContact CD1-CG1 4.34Å; Y464-I469 HydrophobicContact CE1-CD1 3.32Å; Y464-I469 HydrophobicContact CE1-CG1 3.84Å; Y464-I469 PolarHBondContact O-N 3.46Å
465	Y	93.3	Very high	90	Very high	123 Å²	123	77 Å²	77	48%	0.482	38%	0.377	S	S	.	.	I	π-helix	trans	-64.3	-38.5	178.9	-76.5	-78.5	0	0	0	112.2	V461 P462 I469 W470	V461-Y465 HydrophobicContact CG1-CD2 4.15Å; V461-Y465 HydrophobicContact CG1-CE2 3.9Å; V461-Y465 VanDerWaalsContact O-CD2 3.28Å; V461-Y465 WeakPolarHBondContact O-CD2 3.38Å; V461-Y465 PolarHBondContact O-N 3.01Å; P462-Y465 PolarHBondContact O-N 3.16Å; Y465-I469 HydrophobicContact CD1-CB 4.21Å; Y465-I469 HydrophobicContact CD1-CD1 3.37Å; Y465-I469 HydrophobicContact CD1-CG1 4.33Å; Y465-I469 HydrophobicContact CD1-CG2 4.3Å; Y465-I469 HydrophobicContact CE1-CD1 3.36Å; Y465-I469 HydrophobicContact CG-CD1 4.25Å; Y465-W470 PolarHBondContact O-N 3.37Å; Y465-W470 VanDerWaalsContact O-N 3.08Å
466	L	90.9	Very high	90	Very high	86 Å²	86	79.9 Å²	79.9	45%	0.45	38%	0.382	S	S	.	.	I	π-helix	trans	-74.1	-42.6	-178.9	-174.7	139	0	0	0	113	P462 A463 Y464 W470	P462-L466 VanDerWaalsContact O-CB 3.31Å; P462-L466 WeakPolarHBondContact O-CB 3.44Å; P462-L466 PolarHBondContact O-N 3.34Å; A463-L466 PolarHBondContact O-N 3.2Å; Y464-L466 VanDerWaalsContact C-N 3.32Å; Y464-L466 PolarHBondContact O-N 3.25Å; L466-W470 HydrophobicContact CG-CE3 4.34Å; L466-W470 WeakPolarHBondContact O-CB 3.49Å
467	F	87.9	Confident	90	Very high	84 Å²	84	80.6 Å²	80.6	37%	0.368	38%	0.383	S	S	.	.	I	π-helix	trans	-91.7	-31	-174.9	-68.1	-60.7	0	0	0	113.8	W128 A463 K473	W128-F467 HydrophobicContact CH2-CE2 4.12Å; W128-F467 HydrophobicContact CZ3-CD2 4.4Å; W128-F467 HydrophobicContact CZ3-CE2 4.21Å; A463-F467 HydrophobicContact CB-CD2 4.07Å; A463-F467 HydrophobicContact CB-CE2 4.27Å; A463-F467 WeakPolarHBondContact O-CB 3.44Å; A463-F467 VanDerWaalsContact O-CD2 3.22Å; A463-F467 WeakPolarHBondContact O-CD2 3.36Å; A463-F467 PolarHBondContact O-N 2.93Å; F467-K473 WeakPolarHBondContact O-CE 3.33Å; F467-K473 PolarHBondContact O-NZ 3.01Å
468	I	88.4	Confident	89.7	Confident	49 Å²	49	85.1 Å²	85.1	25%	0.251	40%	0.399	S	S	.	.	I	π-helix	trans	-106.3	-53.7	-172.1	-50.4	-54.4	0	0	0	112	F124 G349 Y464	F124-I468 HydrophobicContact CD2-CD1 4.2Å; F124-I468 HydrophobicContact CD2-CG1 3.78Å; F124-I468 HydrophobicContact CE2-CD1 3.98Å; F124-I468 HydrophobicContact CE2-CG1 3.76Å; G349-I468 VanDerWaalsContact O-CD1 3.27Å; G349-I468 WeakPolarHBondContact O-CD1 3.12Å; Y464-I468 HydrophobicContact CD2-CB 3.8Å; Y464-I468 HydrophobicContact CD2-CG1 3.6Å; Y464-I468 HydrophobicContact CD2-CG2 4.29Å; Y464-I468 HydrophobicContact CE2-CB 3.72Å; Y464-I468 HydrophobicContact CE2-CG1 3.84Å; Y464-I468 HydrophobicContact CE2-CG2 3.69Å; Y464-I468 WeakPolarHBondContact O-CA 3.16Å; Y464-I468 VanDerWaalsContact O-CB 3.26Å; Y464-I468 WeakPolarHBondContact O-CB 2.98Å; Y464-I468 PolarHBondContact O-N 2.81Å
469	I	89.8	Confident	89.5	Confident	77 Å²	77	86.1 Å²	86.1	40%	0.395	40%	0.404	S	S	.	.	I	π-helix	trans	-78.3	-26.7	-174.1	-69.3	172.7	0	0	0	112.7	Y464 Y465 D471	Y464-I469 HydrophobicContact CD1-CD1 3.78Å; Y464-I469 HydrophobicContact CD1-CG1 4.34Å; Y464-I469 HydrophobicContact CE1-CD1 3.32Å; Y464-I469 HydrophobicContact CE1-CG1 3.84Å; Y464-I469 PolarHBondContact O-N 3.46Å; Y465-I469 HydrophobicContact CD1-CB 4.21Å; Y465-I469 HydrophobicContact CD1-CD1 3.37Å; Y465-I469 HydrophobicContact CD1-CG1 4.33Å; Y465-I469 HydrophobicContact CD1-CG2 4.3Å; Y465-I469 HydrophobicContact CE1-CD1 3.36Å; Y465-I469 HydrophobicContact CG-CD1 4.25Å; I469-D471 PolarHBondContact O-N 3.4Å
470	W	87.6	Confident	89.2	Confident	118 Å²	118	87.2 Å²	87.2	45%	0.447	41%	0.406	S	S	.	.			trans	-69.9	96	-175.3	-171.1	21.4	0	0	0	112.1	Y465 L466 K472 K473 P474	Y465-W470 PolarHBondContact O-N 3.37Å; Y465-W470 VanDerWaalsContact O-N 3.08Å; L466-W470 HydrophobicContact CG-CE3 4.34Å; L466-W470 WeakPolarHBondContact O-CB 3.49Å; W470-K472 PolarHBondContact NE1-O 2.92Å; W470-K473 HydrophobicContact CD2-CG 4.4Å; W470-K473 HydrophobicContact CE3-CG 4.4Å; W470-K473 WeakPolarHBondContact O-CE 3.45Å; W470-K473 WeakPolarHBondContact O-CG 3.1Å; W470-P474 HydrophobicContact CH2-CG 4.11Å; W470-P474 HydrophobicContact CZ2-CG 4.37Å
471	D	76.1	Confident	88.9	Confident	147 Å²	147	89.7 Å²	89.7	79%	0.786	42%	0.423	S	S	*	.			trans	-71.1	-34	179.9	-67.7	-39	0	0	0	113.1	I469 K473	I469-D471 PolarHBondContact O-N 3.4Å; D471-K473 VanDerWaalsContact C-N 3.26Å; D471-K473 PolarHBondContact O-N 3.09Å; D471-K473 VanDerWaalsContact O-N 3.12Å
472	K	82.4	Confident	88.5	Confident	181 Å²	181	93.3 Å²	93.3	79%	0.787	44%	0.437	S	S	*	.			trans	-89	46.8	-175.7	-65.2	-174.6	-179.4	177.6	0	112.6	W470	W470-K472 PolarHBondContact NE1-O 2.92Å
473	K	85.2	Confident	88.3	Confident	64 Å²	64	97.8 Å²	97.8	28%	0.278	44%	0.443	S	S	.	.			trans	-58.7	134.1	174.8	-65.9	179.4	-174.8	171.7	0	109.9	F467 W470 D471 K475 F477 R478	F467-K473 WeakPolarHBondContact O-CE 3.33Å; F467-K473 PolarHBondContact O-NZ 3.01Å; W470-K473 HydrophobicContact CD2-CG 4.4Å; W470-K473 HydrophobicContact CE3-CG 4.4Å; W470-K473 WeakPolarHBondContact O-CE 3.45Å; W470-K473 WeakPolarHBondContact O-CG 3.1Å; D471-K473 VanDerWaalsContact C-N 3.26Å; D471-K473 PolarHBondContact O-N 3.09Å; D471-K473 VanDerWaalsContact O-N 3.12Å; K473-K475 PolarHBondContact O-N 3.39Å; K473-F477 HydrophobicContact CB-CD1 4.41Å; K473-F477 HydrophobicContact CD-CD1 4.28Å; K473-F477 HydrophobicContact CD-CE1 4.26Å; K473-R478 HydrophobicContact CB-CG 4.05Å
474	P	89.1	Confident	88.2	Confident	42 Å²	42	101.5 Å²	101.5	27%	0.273	46%	0.461	S	S	.	.			trans	-53.1	140.4	177.7	-26.6	34.1	0	0	0	111.9	W470 W476 F477 R478	W470-P474 HydrophobicContact CH2-CG 4.11Å; W470-P474 HydrophobicContact CZ2-CG 4.37Å; P474-W476 HydrophobicContact CB-CG 4.21Å; P474-W476 PolarHBondContact O-N 3.47Å; P474-F477 HydrophobicContact CB-CB 4.37Å; P474-F477 WeakPolarHBondContact O-CB 3.42Å; P474-F477 PolarHBondContact O-N 3.45Å; P474-R478 PolarHBondContact O-N 3.44Å; P474-R478 VanDerWaalsContact O-N 3.16Å
475	K	87.6	Confident	87.9	Confident	175 Å²	175	101.6 Å²	101.6	76%	0.761	46%	0.464	S	S	*	.	H	α-helix	trans	-55.3	-40.9	-179	-69.8	-175.7	179.8	179.8	0	112.1	K473 F477 R478 I479	K473-K475 PolarHBondContact O-N 3.39Å; K475-F477 VanDerWaalsContact C-N 3.29Å; K475-F477 PolarHBondContact O-N 3.29Å; K475-R478 PolarHBondContact O-N 2.68Å; K475-I479 WeakPolarHBondContact O-CD1 3.48Å; K475-I479 VanDerWaalsContact O-CG1 3.26Å; K475-I479 WeakPolarHBondContact O-CG1 3.29Å; K475-I479 PolarHBondContact O-N 2.94Å
476	W	90.8	Very high	87.8	Confident	166 Å²	166	102.8 Å²	102.8	63%	0.629	47%	0.468	S	S	*	.	H	α-helix	trans	-60	-39.2	177.9	71.2	-99.3	0	0	0	112.2	P474 M480	P474-W476 HydrophobicContact CB-CG 4.21Å; P474-W476 PolarHBondContact O-N 3.47Å; W476-M480 HydrophobicContact CZ3-CE 3.92Å; W476-M480 HydrophobicContact CZ3-SD 4.13Å; W476-M480 VanDerWaalsContact O-CB 3.25Å; W476-M480 WeakPolarHBondContact O-CB 3.49Å; W476-M480 PolarHBondContact O-N 2.68Å
477	F	88.1	Confident	87.8	Confident	60 Å²	60	101.7 Å²	101.7	26%	0.263	47%	0.465	S	S	.	.	H	α-helix	trans	-69.1	-42	179.6	-179	-94.8	0	0	0	111.3	K473 P474 K475 M480 S481	K473-F477 HydrophobicContact CB-CD1 4.41Å; K473-F477 HydrophobicContact CD-CD1 4.28Å; K473-F477 HydrophobicContact CD-CE1 4.26Å; P474-F477 HydrophobicContact CB-CB 4.37Å; P474-F477 WeakPolarHBondContact O-CB 3.42Å; P474-F477 PolarHBondContact O-N 3.45Å; K475-F477 VanDerWaalsContact C-N 3.29Å; K475-F477 PolarHBondContact O-N 3.29Å; F477-M480 HydrophobicContact CD2-CE 3.73Å; F477-M480 HydrophobicContact CE2-CE 3.97Å; F477-M480 PolarHBondContact O-N 3.32Å; F477-S481 WeakPolarHBondContact O-CB 3.48Å; F477-S481 PolarHBondContact O-N 3.49Å
478	R	85	Confident	88	Confident	105 Å²	105	100.8 Å²	100.8	40%	0.396	46%	0.464	S	S	.	.	H	α-helix	trans	-61.3	-48.5	174.9	-72.3	174.4	63.2	179.6	-5.7	111.5	Y15 K473 P474 K475 M480 S481 E482	Y15-R478 PolarHBondContact OH-NE 3.08Å; Y15-R478 PolarHBondContact OH-NH2 3.32Å; K473-R478 HydrophobicContact CB-CG 4.05Å; P474-R478 PolarHBondContact O-N 3.44Å; P474-R478 VanDerWaalsContact O-N 3.16Å; K475-R478 PolarHBondContact O-N 2.68Å; R478-M480 VanDerWaalsContact C-N 3.32Å; R478-M480 PolarHBondContact O-N 3.14Å; R478-S481 PolarHBondContact O-N 3.4Å; R478-E482 WeakPolarHBondContact O-CB 3.39Å; R478-E482 PolarHBondContact O-N 3.43Å
479	I	89	Confident	88.1	Confident	110 Å²	110	101 Å²	101	56%	0.564	46%	0.464	S	S	*	.	H	α-helix	trans	-60.8	-42.8	177.8	-66.3	164.9	0	0	0	110.9	K475 R483	K475-I479 WeakPolarHBondContact O-CD1 3.48Å; K475-I479 VanDerWaalsContact O-CG1 3.26Å; K475-I479 WeakPolarHBondContact O-CG1 3.29Å; K475-I479 PolarHBondContact O-N 2.94Å; I479-R483 VanDerWaalsContact O-CB 3.28Å; I479-R483 WeakPolarHBondContact O-CB 3.34Å; I479-R483 PolarHBondContact O-N 2.92Å
480	M	89.8	Confident	88.1	Confident	79 Å²	79	103.4 Å²	103.4	39%	0.389	48%	0.476	S	S	.	.	H	α-helix	trans	-63.8	-48.6	177	-177.8	-175	71.1	0	0	111.5	W476 F477 R478 E482 R483 I484	W476-M480 HydrophobicContact CZ3-CE 3.92Å; W476-M480 HydrophobicContact CZ3-SD 4.13Å; W476-M480 VanDerWaalsContact O-CB 3.25Å; W476-M480 WeakPolarHBondContact O-CB 3.49Å; W476-M480 PolarHBondContact O-N 2.68Å; F477-M480 HydrophobicContact CD2-CE 3.73Å; F477-M480 HydrophobicContact CE2-CE 3.97Å; F477-M480 PolarHBondContact O-N 3.32Å; R478-M480 VanDerWaalsContact C-N 3.32Å; R478-M480 PolarHBondContact O-N 3.14Å; M480-E482 VanDerWaalsContact C-N 3.33Å; M480-E482 PolarHBondContact O-N 3.42Å; M480-R483 PolarHBondContact O-N 2.96Å; M480-I484 HydrophobicContact CG-CD1 3.83Å; M480-I484 HydrophobicContact CG-CG1 4.48Å; M480-I484 WeakPolarHBondContact O-CB 3.34Å; M480-I484 VanDerWaalsContact O-CG1 3.28Å; M480-I484 WeakPolarHBondContact O-CG1 3.45Å; M480-I484 PolarHBondContact O-N 3.35Å
481	S	87.4	Confident	88.3	Confident	52 Å²	52	103.6 Å²	103.6	36%	0.364	48%	0.484	S	S	.	.	H	α-helix	trans	-59.9	-42.9	178.4	-173.8	0	0	0	0	111.8	F477 R478 I484 T485	F477-S481 WeakPolarHBondContact O-CB 3.48Å; F477-S481 PolarHBondContact O-N 3.49Å; R478-S481 PolarHBondContact O-N 3.4Å; S481-I484 PolarHBondContact O-N 3.25Å; S481-T485 WeakPolarHBondContact O-CB 3.36Å; S481-T485 PolarHBondContact O-N 3.42Å; S481-T485 PolarHBondContact O-OG1 3.29Å
482	E	87.8	Confident	89	Confident	128 Å²	128	97.9 Å²	97.9	60%	0.598	45%	0.454	S	S	*	.	H	α-helix	trans	-66.4	-42.3	177.4	-169.8	177.9	177.5	0	0	111.3	R478 M480 T485 R486	R478-E482 WeakPolarHBondContact O-CB 3.39Å; R478-E482 PolarHBondContact O-N 3.43Å; M480-E482 VanDerWaalsContact C-N 3.33Å; M480-E482 PolarHBondContact O-N 3.42Å; E482-T485 PolarHBondContact O-N 3.02Å; E482-R486 VanDerWaalsContact O-CB 3.32Å; E482-R486 WeakPolarHBondContact O-CB 3.48Å; E482-R486 PolarHBondContact O-N 3Å
483	R	91.3	Very high	89.4	Confident	172 Å²	172	92.6 Å²	92.6	65%	0.649	43%	0.432	S	S	*	.	H	α-helix	trans	-62.2	-45.5	175.1	-170.8	176.3	-175.9	174.1	1.6	111.7	I479 M480 R486 T487	I479-R483 VanDerWaalsContact O-CB 3.28Å; I479-R483 WeakPolarHBondContact O-CB 3.34Å; I479-R483 PolarHBondContact O-N 2.92Å; M480-R483 PolarHBondContact O-N 2.96Å; R483-R486 PolarHBondContact O-N 3.03Å; R483-T487 WeakPolarHBondContact O-CB 3.42Å; R483-T487 PolarHBondContact O-N 2.91Å; R483-T487 PolarHBondContact O-OG1 2.99Å; R483-T487 VanDerWaalsContact O-OG1 3.05Å
484	I	90.4	Very high	89.6	Confident	88 Å²	88	89.9 Å²	89.9	45%	0.451	42%	0.421	S	S	.	.	H	α-helix	trans	-60.6	-48.8	175.9	-70.3	167.5	0	0	0	110	M480 S481 R486 T487 L488	M480-I484 HydrophobicContact CG-CD1 3.83Å; M480-I484 HydrophobicContact CG-CG1 4.48Å; M480-I484 WeakPolarHBondContact O-CB 3.34Å; M480-I484 VanDerWaalsContact O-CG1 3.28Å; M480-I484 WeakPolarHBondContact O-CG1 3.45Å; M480-I484 PolarHBondContact O-N 3.35Å; S481-I484 PolarHBondContact O-N 3.25Å; I484-R486 PolarHBondContact O-N 3.45Å; I484-T487 PolarHBondContact O-N 2.9Å; I484-L488 HydrophobicContact CG2-CD1 3.84Å; I484-L488 HydrophobicContact CG2-CG 4.35Å; I484-L488 WeakPolarHBondContact O-CB 3.45Å; I484-L488 WeakPolarHBondContact O-CG 3.26Å; I484-L488 PolarHBondContact O-N 3.19Å
485	T	89.3	Confident	89.5	Confident	27 Å²	27	90.5 Å²	90.5	17%	0.166	42%	0.424	C	S	.	.	H	α-helix	trans	-59.5	-46.9	-179.9	-57.3	0	0	0	0	110.9	I354 M357 S481 E482 T487 L488 Q489	I354-T485 HydrophobicContact CB-CG2 4.3Å; I354-T485 HydrophobicContact CD1-CG2 4.4Å; M357-T485 HydrophobicContact CE-CG2 4.07Å; S481-T485 WeakPolarHBondContact O-CB 3.36Å; S481-T485 PolarHBondContact O-N 3.42Å; S481-T485 PolarHBondContact O-OG1 3.29Å; E482-T485 PolarHBondContact O-N 3.02Å; T485-T487 PolarHBondContact O-N 3.13Å; T485-L488 PolarHBondContact O-N 3.48Å; T485-Q489 WeakPolarHBondContact O-CB 3.14Å; T485-Q489 VanDerWaalsContact O-CG 3.31Å; T485-Q489 WeakPolarHBondContact O-CG 3.49Å; T485-Q489 PolarHBondContact O-N 3.27Å
486	R	89.4	Confident	89.2	Confident	148 Å²	148	85.2 Å²	85.2	56%	0.558	41%	0.407	S	S	*	.	H	α-helix	trans	-63.5	-42.1	177.3	-169.9	-179.9	71.8	-171.3	4.3	112.5	E482 R483 I484 Q489 I490	E482-R486 VanDerWaalsContact O-CB 3.32Å; E482-R486 WeakPolarHBondContact O-CB 3.48Å; E482-R486 PolarHBondContact O-N 3Å; R483-R486 PolarHBondContact O-N 3.03Å; I484-R486 PolarHBondContact O-N 3.45Å; R486-Q489 WeakPolarHBondContact O-CB 3.49Å; R486-Q489 PolarHBondContact O-N 3.03Å; R486-I490 HydrophobicContact CG-CD1 4.18Å; R486-I490 VanDerWaalsContact O-CG1 3.29Å; R486-I490 WeakPolarHBondContact O-CG1 3.47Å; R486-I490 PolarHBondContact O-N 3.42Å
487	T	92.1	Very high	88.1	Confident	64 Å²	64	79.5 Å²	79.5	39%	0.393	39%	0.387	S	S	.	.	H	α-helix	trans	-62.7	-44.3	175.8	-67	0	0	0	0	110.9	R483 I484 T485 I490 I491	R483-T487 WeakPolarHBondContact O-CB 3.42Å; R483-T487 PolarHBondContact O-N 2.91Å; R483-T487 PolarHBondContact O-OG1 2.99Å; R483-T487 VanDerWaalsContact O-OG1 3.05Å; I484-T487 PolarHBondContact O-N 2.9Å; T485-T487 PolarHBondContact O-N 3.13Å; T487-I490 PolarHBondContact O-N 2.92Å; T487-I491 HydrophobicContact CG2-CD1 3.64Å; T487-I491 HydrophobicContact CG2-CG1 4.38Å; T487-I491 WeakPolarHBondContact O-CB 3.08Å; T487-I491 VanDerWaalsContact O-CG1 3.25Å; T487-I491 WeakPolarHBondContact O-CG1 3.49Å; T487-I491 PolarHBondContact O-N 2.98Å
488	L	91.1	Very high	86.9	Confident	65 Å²	65	80.6 Å²	80.6	34%	0.34	39%	0.393	S	S	.	.	H	α-helix	trans	-65.1	-39.2	176	-70.5	174.4	0	0	0	112.3	I354 I484 T485 I490 I491 L492	I354-L488 HydrophobicContact CD1-CB 3.99Å; I354-L488 HydrophobicContact CG1-CB 4.15Å; I354-L488 HydrophobicContact CG1-CD1 4.29Å; I484-L488 HydrophobicContact CG2-CD1 3.84Å; I484-L488 HydrophobicContact CG2-CG 4.35Å; I484-L488 WeakPolarHBondContact O-CB 3.45Å; I484-L488 WeakPolarHBondContact O-CG 3.26Å; I484-L488 PolarHBondContact O-N 3.19Å; T485-L488 PolarHBondContact O-N 3.48Å; L488-I490 VanDerWaalsContact C-N 3.34Å; L488-I490 PolarHBondContact O-N 3.36Å; L488-I491 PolarHBondContact O-N 3.14Å; L488-L492 HydrophobicContact CB-CD1 4.5Å; L488-L492 WeakPolarHBondContact O-CB 3.42Å; L488-L492 VanDerWaalsContact O-CG 3.25Å; L488-L492 WeakPolarHBondContact O-CG 3.49Å; L488-L492 PolarHBondContact O-N 2.9Å
489	Q	90.3	Very high	85.1	Confident	53 Å²	53	82.6 Å²	82.6	25%	0.248	41%	0.412	C	S	.	.	H	α-helix	trans	-56.9	-47.5	174.1	-80.5	173.6	-28.7	0	0	112	I354 M357 T485 R486 E493 V494	I354-Q489 HydrophobicContact CD1-CG 3.91Å; M357-Q489 HydrophobicContact CE-CG 4.25Å; M357-Q489 HydrophobicContact SD-CG 3.45Å; M357-Q489 WeakPolarHBondContact SD-CG 3.32Å; M357-Q489 PolarHBondContact SD-NE2 3.18Å; T485-Q489 WeakPolarHBondContact O-CB 3.14Å; T485-Q489 VanDerWaalsContact O-CG 3.31Å; T485-Q489 WeakPolarHBondContact O-CG 3.49Å; T485-Q489 PolarHBondContact O-N 3.27Å; R486-Q489 WeakPolarHBondContact O-CB 3.49Å; R486-Q489 PolarHBondContact O-N 3.03Å; Q489-E493 WeakPolarHBondContact O-CA 3.42Å; Q489-E493 PolarHBondContact O-N 2.82Å; Q489-V494 HydrophobicContact CB-CG2 4.49Å; Q489-V494 HydrophobicContact CG-CG2 4.24Å; Q489-V494 PolarHBondContact O-N 2.95Å
490	I	90.7	Very high	82.7	Confident	127 Å²	127	84.8 Å²	84.8	65%	0.651	42%	0.417	S	S	*	.	H	α-helix	trans	-67.1	-46.8	-180	-65.2	165.1	0	0	0	110.7	R486 T487 L488 L492	R486-I490 HydrophobicContact CG-CD1 4.18Å; R486-I490 VanDerWaalsContact O-CG1 3.29Å; R486-I490 WeakPolarHBondContact O-CG1 3.47Å; R486-I490 PolarHBondContact O-N 3.42Å; T487-I490 PolarHBondContact O-N 2.92Å; L488-I490 VanDerWaalsContact C-N 3.34Å; L488-I490 PolarHBondContact O-N 3.36Å; I490-L492 PolarHBondContact O-N 3.3Å
491	I	92.2	Very high	79.7	Confident	122 Å²	122	92.2 Å²	92.2	63%	0.626	46%	0.458	S	S	*	.	H	α-helix	trans	-63.8	-41.4	-178.7	-69.8	171.2	0	0	0	111.4	T487 L488	T487-I491 HydrophobicContact CG2-CD1 3.64Å; T487-I491 HydrophobicContact CG2-CG1 4.38Å; T487-I491 WeakPolarHBondContact O-CB 3.08Å; T487-I491 VanDerWaalsContact O-CG1 3.25Å; T487-I491 WeakPolarHBondContact O-CG1 3.49Å; T487-I491 PolarHBondContact O-N 2.98Å; L488-I491 PolarHBondContact O-N 3.14Å
492	L	89.6	Confident	79.4	Confident	28 Å²	28	94.3 Å²	94.3	15%	0.147	46%	0.462	C	S	.	.	H	α-helix	trans	-91.5	-5.5	-173.7	-59.2	177.1	0	0	0	113.3	H359 L366 P367 I370 L488 I490 V494	H359-L492 PolarHBondContact CD2-O 3.07Å; L366-L492 HydrophobicContact CD2-CB 4.2Å; L366-L492 HydrophobicContact CD2-CD2 4Å; P367-L492 HydrophobicContact CB-CD1 4.28Å; P367-L492 HydrophobicContact CG-CD1 3.95Å; I370-L492 HydrophobicContact CD1-CD1 4.19Å; I370-L492 HydrophobicContact CD1-CD2 3.52Å; L488-L492 HydrophobicContact CB-CD1 4.5Å; L488-L492 WeakPolarHBondContact O-CB 3.42Å; L488-L492 VanDerWaalsContact O-CG 3.25Å; L488-L492 WeakPolarHBondContact O-CG 3.49Å; L488-L492 PolarHBondContact O-N 2.9Å; I490-L492 PolarHBondContact O-N 3.3Å; L492-V494 VanDerWaalsContact C-N 3.3Å; L492-V494 HydrophobicContact CB-CG1 3.76Å; L492-V494 HydrophobicContact CB-CG2 4.14Å; L492-V494 WeakPolarHBondContact O-CG1 3.5Å; L492-V494 PolarHBondContact O-N 3.21Å
493	E	91.2	Very high	78.9	Confident	70 Å²	70	92.5 Å²	92.5	33%	0.327	46%	0.455	S	S	.	.	T	Hydrogen-bonded Turn	trans	50.9	49.5	-174.2	-160.5	-174.5	-163.9	0	0	111.3	H359 V360 R361 Q489	H359-E493 WeakPolarHBondContact CA-O 3.46Å; H359-E493 IonicContact CE1-OE2 3.39Å; H359-E493 PolarHBondContact CE1-OE2 3.47Å; H359-E493 VanDerWaalsContact CE1-OE2 3.31Å; V360-E493 HydrophobicContact CB-CG 4.32Å; V360-E493 HydrophobicContact CG2-CG 4.36Å; V360-E493 WeakPolarHBondContact CG2-O 3.36Å; V360-E493 PolarHBondContact N-O 3.44Å; R361-E493 IonicContact CZ-OE1 3.8Å; R361-E493 IonicContact CZ-OE2 3.74Å; R361-E493 IonicContact NE-OE1 3.05Å; R361-E493 PolarHBondContact NE-OE1 2.7Å; R361-E493 IonicContact NE-OE2 2.68Å; R361-E493 PolarHBondContact NE-OE2 3.36Å; R361-E493 IonicContact NH2-OE1 3.97Å; R361-E493 PolarHBondContact NH2-OE1 2.81Å; R361-E493 IonicContact NH2-OE2 3.83Å; Q489-E493 WeakPolarHBondContact O-CA 3.42Å; Q489-E493 PolarHBondContact O-N 2.82Å
494	V	89.4	Confident	78.2	Confident	7 Å²	7	88.1 Å²	88.1	4%	0.042	44%	0.444	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.7	146.1	-177.5	-60.7	0	0	0	0	112.3	I354 M357 I358 H359 L366 P367 Q489 L492	I354-V494 HydrophobicContact CD1-CG2 3.86Å; M357-V494 HydrophobicContact CB-CB 3.84Å; M357-V494 HydrophobicContact CB-CG2 3.81Å; M357-V494 HydrophobicContact SD-CG2 4.14Å; I358-V494 CarbonylContact O-C 3.58Å; I358-V494 VanDerWaalsContact O-CA 3.27Å; I358-V494 WeakPolarHBondContact O-CA 3.49Å; H359-V494 HydrophobicContact CB-CG1 4.24Å; L366-V494 HydrophobicContact CB-CG1 4.49Å; P367-V494 HydrophobicContact CG-CB 4.47Å; P367-V494 HydrophobicContact CG-CG1 3.95Å; P367-V494 HydrophobicContact CG-CG2 4.15Å; Q489-V494 HydrophobicContact CB-CG2 4.49Å; Q489-V494 HydrophobicContact CG-CG2 4.24Å; Q489-V494 PolarHBondContact O-N 2.95Å; L492-V494 VanDerWaalsContact C-N 3.3Å; L492-V494 HydrophobicContact CB-CG1 3.76Å; L492-V494 HydrophobicContact CB-CG2 4.14Å; L492-V494 WeakPolarHBondContact O-CG1 3.5Å; L492-V494 PolarHBondContact O-N 3.21Å
495	V	86.6	Confident	77.5	Confident	55 Å²	55	88.1 Å²	88.1	33%	0.333	44%	0.444	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-126	149.1	179.7	-68.9	0	0	0	0	111.1	M357 I358 V360	M357-V495 CarbonylContact C-O 3.6Å; M357-V495 VanDerWaalsContact CA-O 3.31Å; M357-V495 WeakPolarHBondContact CA-O 3.5Å; M357-V495 WeakPolarHBondContact CB-O 3.46Å; I358-V495 PolarHBondContact N-O 3.38Å; I358-V495 PolarHBondContact O-N 3.2Å; V360-V495 HydrophobicContact CG2-CB 4.37Å; V360-V495 HydrophobicContact CG2-CG1 3.61Å; V360-V495 HydrophobicContact CG2-CG2 3.92Å
496	P	81.4	Confident	76.8	Confident	64 Å²	64	91.9 Å²	91.9	42%	0.416	46%	0.461	S	S	.	.	P	Polyproline II helix	trans	-63.5	156.4	170.4	28	-33.5	0	0	0	111.2
497	E	68.8	Low	75.9	Confident	46 Å²	46	88.1 Å²	88.1	22%	0.215	46%	0.455	C	S	.	.	P	Polyproline II helix	trans	-65.9	140.4	174	-168.1	-178.8	-161.8	0	0	109.6	Y343 D499	Y343-E497 WeakPolarHBondContact OH-CG 3.43Å; Y343-E497 PolarHBondContact OH-OE1 3.04Å; Y343-E497 PolarHBondContact OH-OE2 3.02Å; E497-D499 PolarHBondContact O-N 3.06Å
498	E	62.1	Low	74.8	Confident	82 Å²	82	89.9 Å²	89.9	38%	0.383	46%	0.459	S	S	.	.	P	Polyproline II helix	trans	-69.9	120.1	170.4	-75.1	-178	162.7	0	0	109.3	K500	E498-K500 PolarHBondContact O-N 3.09Å
499	D	46.5	Very low	73.5	Confident	148 Å²	148	91.8 Å²	91.8	79%	0.791	47%	0.468	S	S	*	.	P	Polyproline II helix	trans	-52.5	138.1	179.6	-82.2	-35.2	0	0	0	111.7	E497 L501	E497-D499 PolarHBondContact O-N 3.06Å; D499-L501 VanDerWaalsContact C-N 3.26Å; D499-L501 PolarHBondContact O-N 2.91Å
500	K	38.8	Very low	72.1	Confident	155 Å²	155	95 Å²	95	67%	0.674	49%	0.487	S	S	*	.			trans	-67.1	88.9	165	-70.4	177.9	-177.7	170.9	0	107.9	E498	E498-K500 PolarHBondContact O-N 3.09Å
501	L	28.5	Very low	70.5	Confident	236 Å²	236	92.1 Å²	92.1	100%	1.236	47%	0.472	S	S	*	.			trans	-59.3	0	166.8	-84.4	163.5	0	0	0	111.3	D499	D499-L501 VanDerWaalsContact C-N 3.26Å; D499-L501 PolarHBondContact O-N 2.91Å

Retrieved 501 of 501 residues in 101.6 ms (Link to these results)

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