A0A2K5L6H7_CERAT Loading...

Bardet-Biedl syndrome 7 protein homolog

The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.

AlphaFold DB , UniProt , Accession A0A2K5L6H7, Species CERAT (Cercocebus atys, Sooty mangabey), Gene BBS7, Length 715 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M60.3Low87.1Confident206 Ų20672.5 Ų72.5100%1.01536%0.358SS*.  01440-72.2-170.4-155.600106.5
2D78.4Confident87.8Confident104 Ų10474.8 Ų74.856%0.55637%0.366SS*.  trans-75.4134.4177.6-57.3-32.1000109.3R280D2-R280 IonicContact OD1-NH1 3.93Å
3P83.6Confident88.5Confident20 Ų2070.6 Ų70.613%0.1335%0.348CS..  trans-72132.6-175.828.8-31.9000110.1L5 R280 F281P3-L5 HydrophobicContact CB-CD2 4.48Å; P3-L5 HydrophobicContact CB-CG 4.37Å; P3-R280 HydrophobicContact CG-CB 4.39Å; P3-F281 HydrophobicContact CG-CB 3.89Å; P3-F281 WeakPolarHBondContact O-CD2 3.45Å
4I88.6Confident89Confident139 Ų13967 Ų6771%0.71334%0.338SS*.  trans-94.2109.6171.9-59.2174.8000107.2
5L93.3Very high89.5Confident13 Ų1363.1 Ų63.17%0.06832%0.319CS..  trans-112.9133-179.3-56.9176.9000111.1P3 I249 F281 I305 L317 T318 T319P3-L5 HydrophobicContact CB-CD2 4.48Å; P3-L5 HydrophobicContact CB-CG 4.37Å; L5-I249 HydrophobicContact CD2-CD1 4.28Å; L5-I249 HydrophobicContact CD2-CG1 4.15Å; L5-F281 HydrophobicContact CB-CE1 4.5Å; L5-F281 HydrophobicContact CB-CE2 3.94Å; L5-F281 HydrophobicContact CB-CZ 3.87Å; L5-F281 HydrophobicContact CD1-CD1 4.02Å; L5-F281 HydrophobicContact CD1-CD2 4.47Å; L5-F281 HydrophobicContact CD1-CE1 3.94Å; L5-F281 HydrophobicContact CD1-CE2 4.41Å; L5-F281 HydrophobicContact CD1-CG 4.28Å; L5-F281 HydrophobicContact CD1-CZ 4.13Å; L5-F281 HydrophobicContact CG-CE2 4.34Å; L5-F281 HydrophobicContact CG-CZ 4.4Å; L5-I305 HydrophobicContact CD1-CD1 3.53Å; L5-I305 HydrophobicContact CD1-CG1 4.22Å; L5-L317 HydrophobicContact CB-CB 3.93Å; L5-L317 HydrophobicContact CD1-CB 4.18Å; L5-T318 WeakPolarHBondContact CA-O 3.23Å; L5-T319 HydrophobicContact CD2-CG2 3.67Å
6N92.2Very high90Very high39 Ų3959.2 Ų59.221%0.20930%0.299CS..EExtended strand (participates in β ladder)trans-107129-174.5-80.2-36.4000110.3L317 T318 E320 I322N6-L317 CarbonylContact O-C 3.59Å; N6-L317 WeakPolarHBondContact O-CA 3.45Å; N6-T318 HydrophobicContact CB-CG2 4.17Å; N6-T318 PolarHBondContact N-O 3.45Å; N6-T318 WeakPolarHBondContact O-CG2 3.39Å; N6-T318 PolarHBondContact O-N 3.35Å; N6-E320 PolarHBondContact ND2-O 3.5Å; N6-I322 HydrophobicContact CB-CD1 3.46Å; N6-I322 VanDerWaalsContact CB-CD1 3.46Å; N6-I322 HydrophobicContact CB-CG1 3.64Å
7R92.7Very high90.5Very high113 Ų11356.6 Ų56.643%0.42629%0.288SS..EExtended strand (participates in β ladder)trans-73.6129.1-179.8-177.7177.7169.8174.4-2.8111.5D9 T315 G316 L317R7-D9 IonicContact CZ-OD1 3.08Å; R7-D9 IonicContact CZ-OD2 3.18Å; R7-D9 IonicContact NE-OD1 2.64Å; R7-D9 PolarHBondContact NE-OD1 3.3Å; R7-D9 IonicContact NE-OD2 3.49Å; R7-D9 IonicContact NH2-OD1 2.98Å; R7-D9 PolarHBondContact NH2-OD1 3.23Å; R7-D9 VanDerWaalsContact NH2-OD1 3.08Å; R7-D9 IonicContact NH2-OD2 3.52Å; R7-D9 PolarHBondContact NH2-OD2 3.11Å; R7-T315 HydrophobicContact CG-CG2 3.61Å; R7-G316 CarbonylContact C-O 3.55Å; R7-G316 WeakPolarHBondContact CA-O 3.29Å; R7-L317 HydrophobicContact CB-CD2 4.12Å; R7-L317 HydrophobicContact CG-CD2 4.34Å
8M90.6Very high90.9Very high61 Ų6155.8 Ų55.830%0.328%0.283SS..EExtended strand (participates in β ladder)trans-135.3122.3170.8177.5168.547.500110.3Y10 T315 G316 T318M8-Y10 HydrophobicContact CE-CE1 3.46Å; M8-Y10 VanDerWaalsContact CE-CE1 3.46Å; M8-Y10 WeakPolarHBondContact CE-OH 3.49Å; M8-Y10 HydrophobicContact CG-CD1 4.39Å; M8-Y10 HydrophobicContact CG-CE1 4.02Å; M8-Y10 HydrophobicContact SD-CE1 3.99Å; M8-T315 CarbonylContact O-C 3.6Å; M8-G316 PolarHBondContact N-O 3.02Å; M8-G316 PolarHBondContact O-N 3.15Å; M8-T318 HydrophobicContact CE-CG2 4.3Å
9D91.8Very high91.2Very high54 Ų5454.3 Ų54.329%0.28927%0.274SS..EExtended strand (participates in β ladder)trans-91.3127.4178.6-61.3-38.9000110.8R7 W313 T315R7-D9 IonicContact CZ-OD1 3.08Å; R7-D9 IonicContact CZ-OD2 3.18Å; R7-D9 IonicContact NE-OD1 2.64Å; R7-D9 PolarHBondContact NE-OD1 3.3Å; R7-D9 IonicContact NE-OD2 3.49Å; R7-D9 IonicContact NH2-OD1 2.98Å; R7-D9 PolarHBondContact NH2-OD1 3.23Å; R7-D9 VanDerWaalsContact NH2-OD1 3.08Å; R7-D9 IonicContact NH2-OD2 3.52Å; R7-D9 PolarHBondContact NH2-OD2 3.11Å; D9-W313 HydrophobicContact CB-CE3 4.35Å; D9-W313 HydrophobicContact CB-CZ3 4.33Å; D9-T315 WeakPolarHBondContact OD1-CB 3.32Å; D9-T315 WeakPolarHBondContact OD1-CG2 3.37Å; D9-T315 PolarHBondContact OD1-OG1 2.91Å
10Y93Very high91.6Very high22 Ų2251.6 Ų51.69%0.08626%0.26CS..EExtended strand (participates in β ladder)trans-91.9-64.5-175.1-63.5-52.1000113M8 M49 V297 G298 E304 V314M8-Y10 HydrophobicContact CE-CE1 3.46Å; M8-Y10 VanDerWaalsContact CE-CE1 3.46Å; M8-Y10 WeakPolarHBondContact CE-OH 3.49Å; M8-Y10 HydrophobicContact CG-CD1 4.39Å; M8-Y10 HydrophobicContact CG-CE1 4.02Å; M8-Y10 HydrophobicContact SD-CE1 3.99Å; Y10-M49 HydrophobicContact CD1-CE 3.66Å; Y10-M49 HydrophobicContact CD1-CG 4.29Å; Y10-M49 HydrophobicContact CD1-SD 3.65Å; Y10-M49 HydrophobicContact CE1-CE 4.03Å; Y10-M49 HydrophobicContact CE1-CG 4.28Å; Y10-M49 HydrophobicContact CE1-SD 4.2Å; Y10-M49 HydrophobicContact CG-SD 4.31Å; Y10-V297 HydrophobicContact CE2-CB 4.37Å; Y10-V297 HydrophobicContact CE2-CG1 4.29Å; Y10-G298 WeakPolarHBondContact OH-CA 3.42Å; Y10-G298 PolarHBondContact OH-N 2.75Å; Y10-E304 WeakPolarHBondContact CE2-OE1 3.43Å; Y10-E304 PolarHBondContact OH-OE1 2.82Å; Y10-E304 PolarHBondContact OH-OE2 2.86Å; Y10-V314 WeakPolarHBondContact CB-O 3.48Å; Y10-V314 HydrophobicContact CD2-CG1 4.26Å; Y10-V314 PolarHBondContact N-O 2.74Å
11L94Very high91.9Very high27 Ų2749.2 Ų49.214%0.14125%0.249CC..EExtended strand (participates in β ladder)trans-156161.9179.38687.3000110.4V13 M45 F47 A54 V314L11-V13 HydrophobicContact CD1-CB 4.42Å; L11-V13 HydrophobicContact CD1-CG1 3.37Å; L11-M45 HydrophobicContact CD1-CE 4.48Å; L11-M45 HydrophobicContact CD1-SD 4.36Å; L11-M45 HydrophobicContact CD2-CE 3.68Å; L11-M45 HydrophobicContact CD2-SD 4.38Å; L11-F47 HydrophobicContact CD2-CB 4.12Å; L11-F47 HydrophobicContact CD2-CD1 3.23Å; L11-F47 HydrophobicContact CD2-CD2 3.81Å; L11-F47 HydrophobicContact CD2-CE1 3.33Å; L11-F47 HydrophobicContact CD2-CE2 3.93Å; L11-F47 HydrophobicContact CD2-CG 3.45Å; L11-F47 VanDerWaalsContact CD2-CG 3.45Å; L11-F47 HydrophobicContact CD2-CZ 3.69Å; L11-F47 HydrophobicContact CG-CD1 4.31Å; L11-F47 HydrophobicContact CG-CE1 3.96Å; L11-F47 HydrophobicContact CG-CZ 4.16Å; L11-A54 HydrophobicContact CB-CB 4.23Å; L11-A54 HydrophobicContact CD2-CB 4.03Å; L11-V314 PolarHBondContact O-N 2.95Å
12Q95.1Very high93.7Very high99 Ų9940.7 Ų40.746%0.46321%0.206SC..EExtended strand (participates in β ladder)trans-112.4125.3173.4-166.1-177.71100110.3S311 G312 W313Q12-S311 PolarHBondContact NE2-O 3.13Å; Q12-G312 CarbonylContact C-O 3.59Å; Q12-G312 WeakPolarHBondContact CA-O 3.44Å; Q12-W313 HydrophobicContact CB-CD2 4.12Å; Q12-W313 HydrophobicContact CB-CE3 4.07Å; Q12-W313 HydrophobicContact CB-CH2 4.37Å; Q12-W313 HydrophobicContact CB-CZ2 4.41Å; Q12-W313 HydrophobicContact CB-CZ3 4.2Å; Q12-W313 VanDerWaalsContact CD-CE2 3.48Å; Q12-W313 HydrophobicContact CG-CD2 3.99Å; Q12-W313 HydrophobicContact CG-CE3 4.46Å; Q12-W313 HydrophobicContact CG-CG 4.22Å; Q12-W313 HydrophobicContact CG-CZ2 4.38Å
13V96.4Very high94.6Very high21 Ų2136.1 Ų36.113%0.12718%0.181CC..  trans-100.5-174.6170.5-65.40000110.9L11 T16 I37 M45 G312L11-V13 HydrophobicContact CD1-CB 4.42Å; L11-V13 HydrophobicContact CD1-CG1 3.37Å; V13-T16 HydrophobicContact CG2-CG2 3.86Å; V13-I37 HydrophobicContact CG1-CG2 3.7Å; V13-I37 HydrophobicContact CG2-CD1 3.6Å; V13-I37 HydrophobicContact CG2-CG1 4.03Å; V13-I37 HydrophobicContact CG2-CG2 4.26Å; V13-M45 HydrophobicContact CG1-SD 4.31Å; V13-G312 WeakPolarHBondContact CG2-O 3.17Å; V13-G312 PolarHBondContact N-O 2.79Å
14G95.5Very high95.3Very high20 Ų2035.6 Ų35.621%0.20618%0.177CC..SBendtrans-66.8179.6169.100000112.6T16 G312G14-T16 WeakPolarHBondContact O-CG2 3.37Å; G14-T16 PolarHBondContact O-N 3.4Å; G14-G312 WeakPolarHBondContact O-CA 3.44Å
15V97.3Very high95.4Very high8 Ų831.3 Ų31.35%0.04816%0.158CC..  trans-58.8137.5-179.8-176.30000111.1D39 H40 Y310 Q401V15-D39 CarbonylContact O-C 3.55Å; V15-D39 WeakPolarHBondContact O-CA 3.21Å; V15-H40 HydrophobicContact CB-CB 4.28Å; V15-H40 WeakPolarHBondContact CG1-CE1 3.49Å; V15-H40 VanDerWaalsContact CG1-ND1 3.28Å; V15-H40 WeakPolarHBondContact CG1-ND1 3.4Å; V15-H40 WeakPolarHBondContact O-CB 3.46Å; V15-H40 PolarHBondContact O-CD2 3.16Å; V15-H40 VanDerWaalsContact O-CD2 3.23Å; V15-H40 VanDerWaalsContact O-CG 3.25Å; V15-H40 PolarHBondContact O-N 3.04Å; V15-Y310 CarbonylContact C-O 3.56Å; V15-Y310 VanDerWaalsContact CA-O 3.26Å; V15-Y310 WeakPolarHBondContact CA-O 3.15Å; V15-Y310 HydrophobicContact CG1-CD1 4.35Å; V15-Y310 HydrophobicContact CG1-CD2 3.74Å; V15-Y310 HydrophobicContact CG1-CE1 3.99Å; V15-Y310 HydrophobicContact CG1-CE2 3.29Å; V15-Y310 HydrophobicContact CG1-CG 4.25Å; V15-Y310 VanDerWaalsContact CG1-CZ 3.44Å; V15-Y310 VanDerWaalsContact CG1-O 3.3Å; V15-Y310 WeakPolarHBondContact CG1-O 3.09Å; V15-Q401 HydrophobicContact CG2-CB 3.41Å; V15-Q401 VanDerWaalsContact CG2-CB 3.41Å; V15-Q401 HydrophobicContact CG2-CG 4.26Å
16T97.8Very high94.9Very high1 Ų132.6 Ų32.61%0.00617%0.171CC..EExtended strand (participates in β ladder)trans-111.3150.1-174.666.80000112.6V13 G14 I37 H40 T290 T309 Y310V13-T16 HydrophobicContact CG2-CG2 3.86Å; G14-T16 WeakPolarHBondContact O-CG2 3.37Å; G14-T16 PolarHBondContact O-N 3.4Å; T16-I37 HydrophobicContact CG2-CD1 3.98Å; T16-I37 HydrophobicContact CG2-CG1 4.2Å; T16-H40 PolarHBondContact O-NE2 2.94Å; T16-T290 PolarHBondContact OG1-OG1 3.03Å; T16-T309 PolarHBondContact OG1-O 2.73Å; T16-Y310 PolarHBondContact N-O 2.8Å
17S97.6Very high94.2Very high16 Ų1636 Ų3611%0.11220%0.198CC..EExtended strand (participates in β ladder)trans-93.7166.3169.7-76.30000111.5K19 T20 H40 K65S17-K19 PolarHBondContact O-N 3.32Å; S17-T20 PolarHBondContact N-OG1 2.91Å; S17-T20 WeakPolarHBondContact O-CB 3.46Å; S17-T20 WeakPolarHBondContact O-CG2 3.1Å; S17-T20 PolarHBondContact O-N 3.15Å; S17-T20 PolarHBondContact O-OG1 2.81Å; S17-H40 PolarHBondContact N-NE2 2.84Å; S17-H40 PolarHBondContact OG-CD2 3.29Å; S17-H40 PolarHBondContact OG-NE2 3.33Å; S17-K65 WeakPolarHBondContact OG-CE 3.23Å; S17-K65 PolarHBondContact OG-NZ 2.87Å
18Q97.6Very high93.5Very high42 Ų4240.2 Ų40.220%0.19621%0.214CC..EExtended strand (participates in β ladder)trans-55.8131.7176.7-170-15921.900111.9R68 T191 L242 T290Q18-R68 PolarHBondContact O-NH1 3.22Å; Q18-R68 VanDerWaalsContact OE1-NH1 3.13Å; Q18-T191 PolarHBondContact NE2-O 3.43Å; Q18-L242 HydrophobicContact CG-CB 4.35Å; Q18-L242 WeakPolarHBondContact CG-O 3.27Å; Q18-L242 PolarHBondContact NE2-O 3.32Å; Q18-T290 CarbonylContact C-O 3.56Å; Q18-T290 WeakPolarHBondContact CA-O 3.37Å
19K98.1Very high92.7Very high27 Ų2745.2 Ų45.212%0.11724%0.236CC..EExtended strand (participates in β ladder)trans52.953.4-178.9-61.916661176.70112.4S17 L69 D149 V192 L193 C243 T290 S291S17-K19 PolarHBondContact O-N 3.32Å; K19-L69 PolarHBondContact O-N 2.63Å; K19-D149 IonicContact NZ-OD1 3.15Å; K19-D149 IonicContact NZ-OD2 3.47Å; K19-D149 PolarHBondContact NZ-OD2 3.16Å; K19-V192 HydrophobicContact CD-CG2 3.82Å; K19-L193 PolarHBondContact NZ-O 2.83Å; K19-C243 HydrophobicContact CG-CB 4.36Å; K19-T290 PolarHBondContact N-O 2.87Å; K19-S291 VanDerWaalsContact CA-OG 3.27Å; K19-S291 WeakPolarHBondContact CA-OG 3.34Å; K19-S291 PolarHBondContact N-OG 2.77Å
20T98.4Very high91.8Very high0 Ų048 Ų480%024%0.243CC..EExtended strand (participates in β ladder)trans-111.76.1175.255.10000114.1S17 I37 G38 I66 S291S17-T20 PolarHBondContact N-OG1 2.91Å; S17-T20 WeakPolarHBondContact O-CB 3.46Å; S17-T20 WeakPolarHBondContact O-CG2 3.1Å; S17-T20 PolarHBondContact O-N 3.15Å; S17-T20 PolarHBondContact O-OG1 2.81Å; T20-I37 WeakPolarHBondContact O-CA 3.35Å; T20-G38 PolarHBondContact O-N 2.79Å; T20-G38 VanDerWaalsContact O-N 3.09Å; T20-G38 PolarHBondContact OG1-O 2.9Å; T20-I66 HydrophobicContact CG2-CG2 4.29Å; T20-S291 PolarHBondContact N-OG 3.48Å
21M98.5Very high91.5Very high2 Ų247.8 Ų47.81%0.0125%0.245CC..EExtended strand (participates in β ladder)trans-116.7138.1171.2-176.4-79.7-66.700110.8L23 V35 V36 I37 S291 Q293 V306M21-L23 HydrophobicContact SD-CD2 4.18Å; M21-V35 HydrophobicContact CG-CG1 3.69Å; M21-V35 HydrophobicContact SD-CG1 4.02Å; M21-V36 CarbonylContact C-O 3.55Å; M21-V36 VanDerWaalsContact CA-O 3.31Å; M21-V36 WeakPolarHBondContact CA-O 3.3Å; M21-I37 HydrophobicContact CB-CB 4.47Å; M21-I37 HydrophobicContact CB-CD1 4.15Å; M21-I37 HydrophobicContact CB-CG1 4.18Å; M21-I37 HydrophobicContact CG-CB 4.43Å; M21-I37 HydrophobicContact CG-CD1 4.29Å; M21-S291 PolarHBondContact N-OG 3.49Å; M21-Q293 HydrophobicContact CE-CB 4.38Å; M21-V306 HydrophobicContact CE-CB 4.18Å; M21-V306 HydrophobicContact CE-CG1 3.91Å; M21-V306 VanDerWaalsContact CE-O 3.3Å; M21-V306 WeakPolarHBondContact CE-O 3.42Å; M21-V306 HydrophobicContact SD-CG1 4.21Å
22K98.2Very high91.4Very high26 Ų2648.8 Ų48.811%0.11325%0.253CS..EExtended strand (participates in β ladder)trans-141.7151.9172.9-63.7-70.1173.3157.20111.3V36 L69 E70 L71 Q293K22-V36 PolarHBondContact N-O 3.05Å; K22-V36 PolarHBondContact O-N 2.89Å; K22-L69 HydrophobicContact CB-CD2 3.74Å; K22-L69 VanDerWaalsContact CE-O 3.25Å; K22-L69 WeakPolarHBondContact CE-O 3.4Å; K22-L69 HydrophobicContact CG-CD2 3.4Å; K22-E70 VanDerWaalsContact CE-CD 3.5Å; K22-E70 WeakPolarHBondContact CE-OE1 3.37Å; K22-E70 WeakPolarHBondContact CE-OE2 3.45Å; K22-E70 IonicContact NZ-OE1 2.64Å; K22-E70 PolarHBondContact NZ-OE1 2.88Å; K22-E70 IonicContact NZ-OE2 3.43Å; K22-E70 PolarHBondContact NZ-OE2 3.25Å; K22-L71 HydrophobicContact CB-CD1 3.95Å; K22-L71 HydrophobicContact CB-CD2 4.13Å; K22-L71 HydrophobicContact CB-CG 3.78Å; K22-L71 HydrophobicContact CG-CG 4.08Å; K22-Q293 VanDerWaalsContact CD-NE2 3.34Å
23L97.5Very high91.4Very high8 Ų845.6 Ų45.64%0.04224%0.238CC..EExtended strand (participates in β ladder)trans-97.1122.2172.1-58.9-175.1000109.4M21 V35 L71 Q293 V297 V306M21-L23 HydrophobicContact SD-CD2 4.18Å; L23-V35 HydrophobicContact CD2-CB 4.3Å; L23-V35 HydrophobicContact CD2-CG1 4.48Å; L23-V35 HydrophobicContact CD2-CG2 3.66Å; L23-L71 WeakPolarHBondContact O-CD1 3.23Å; L23-Q293 VanDerWaalsContact CB-OE1 3.32Å; L23-Q293 HydrophobicContact CD1-CB 3.9Å; L23-Q293 HydrophobicContact CG-CB 3.97Å; L23-V297 HydrophobicContact CD1-CG2 4.44Å; L23-V297 HydrophobicContact CD2-CG2 3.79Å; L23-V306 HydrophobicContact CD1-CB 4.45Å; L23-V306 HydrophobicContact CD1-CG2 4.06Å; L23-V306 HydrophobicContact CD2-CB 4.3Å; L23-V306 HydrophobicContact CD2-CG1 4.36Å; L23-V306 HydrophobicContact CD2-CG2 4.12Å
24L96.4Very high91.4Very high10 Ų1048.8 Ų48.85%0.05225%0.25CS..EExtended strand (participates in β ladder)trans-65.1142.6171.5-71.3170.2000109.8A26 Q33 K34 V36 L71 I82 K95L24-A26 PolarHBondContact O-N 2.74Å; L24-Q33 WeakPolarHBondContact O-CB 3.41Å; L24-Q33 WeakPolarHBondContact O-CG 3.43Å; L24-Q33 PolarHBondContact O-NE2 2.77Å; L24-K34 HydrophobicContact CB-CB 4.35Å; L24-K34 HydrophobicContact CD1-CB 4.03Å; L24-K34 PolarHBondContact N-O 3.1Å; L24-V36 HydrophobicContact CD1-CG2 3.69Å; L24-V36 HydrophobicContact CD2-CG2 4.25Å; L24-V36 HydrophobicContact CG-CG2 3.68Å; L24-L71 HydrophobicContact CD2-CD1 4.34Å; L24-L71 HydrophobicContact CD2-CD2 3.92Å; L24-I82 HydrophobicContact CD2-CD1 4.31Å; L24-I82 HydrophobicContact CD2-CG1 4.05Å; L24-K95 HydrophobicContact CD1-CB 4.06Å
25P91.6Very high91.5Very high48 Ų4847.9 Ų47.931%0.31224%0.24SC..PPolyproline II helixtrans-54.1139.1179.2-2633.2000112.5P78 Q79 E80P25-P78 HydrophobicContact CB-CB 4.46Å; P25-P78 HydrophobicContact CG-CB 4.46Å; P25-Q79 VanDerWaalsContact CD-O 3.29Å; P25-Q79 WeakPolarHBondContact CD-O 3.24Å; P25-Q79 WeakPolarHBondContact CG-O 3.18Å; P25-E80 HydrophobicContact CG-CG 4.44Å
26A83.6Confident91.6Very high40 Ų4047.5 Ų47.533%0.33124%0.238SC..PPolyproline II helixtrans-66.2143.9177.800000110.9L24 R28 Q33L24-A26 PolarHBondContact O-N 2.74Å; A26-R28 VanDerWaalsContact C-N 3.26Å; A26-R28 VanDerWaalsContact CB-O 3.26Å; A26-R28 WeakPolarHBondContact CB-O 3.05Å; A26-R28 PolarHBondContact O-N 2.78Å; A26-Q33 HydrophobicContact CB-CG 3.7Å
27S76.8Confident91.6Very high111 Ų11147.5 Ų47.578%0.77624%0.238SC*.SBendtrans-72.2-22.1175.964.60000113.4
28R77.9Confident91.7Very high201 Ų20146.7 Ų46.776%0.75823%0.233SC*.SBendtrans-147.1157.1178.1-62.2-178-179.4177-0.9108.6A26 R30 A31A26-R28 VanDerWaalsContact C-N 3.26Å; A26-R28 VanDerWaalsContact CB-O 3.26Å; A26-R28 WeakPolarHBondContact CB-O 3.05Å; A26-R28 PolarHBondContact O-N 2.78Å; R28-R30 PolarHBondContact O-N 3.37Å; R28-A31 HydrophobicContact CB-CB 4.12Å; R28-A31 WeakPolarHBondContact O-CB 3.4Å; R28-A31 PolarHBondContact O-N 3.35Å; R28-A31 VanDerWaalsContact O-N 3.16Å
29H73.9Confident91.7Very high166 Ų16645.2 Ų45.277%0.76923%0.226SC*.THydrogen-bonded Turntrans-53.6127.9174-173.6-82.5000110.3A31H29-A31 PolarHBondContact O-N 3Å
30R72.2Confident91.6Very high113 Ų11346 Ų4643%0.42623%0.23SC..THydrogen-bonded Turntrans59.220179.9-77.5-179.4177.81752.4116.5R28 S301 D303R28-R30 PolarHBondContact O-N 3.37Å; R30-S301 PolarHBondContact O-N 3.07Å; R30-D303 IonicContact CZ-OD2 3.55Å; R30-D303 IonicContact NE-OD2 2.66Å; R30-D303 IonicContact NH2-OD2 2.76Å; R30-D303 PolarHBondContact NH2-OD2 2.88Å
31A87.1Confident91.5Very high18 Ų1850.9 Ų50.915%0.14926%0.256CS..PPolyproline II helixtrans-82.3149.1167.200000110.5R28 H29 Q33R28-A31 HydrophobicContact CB-CB 4.12Å; R28-A31 WeakPolarHBondContact O-CB 3.4Å; R28-A31 PolarHBondContact O-N 3.35Å; R28-A31 VanDerWaalsContact O-N 3.16Å; H29-A31 PolarHBondContact O-N 3Å; A31-Q33 PolarHBondContact O-N 2.96Å
32T92.1Very high91.4Very high48 Ų4850.8 Ų50.829%0.29426%0.256SS..PPolyproline II helixtrans-53.2124.4173.540.90000111.5C296 V297 D300T32-C296 CarbonylContact C-O 3.55Å; T32-C296 WeakPolarHBondContact CA-O 3.34Å; T32-V297 VanDerWaalsContact CG2-O 3.25Å; T32-V297 WeakPolarHBondContact CG2-O 3.43Å; T32-D300 VanDerWaalsContact CB-OD1 3.3Å; T32-D300 WeakPolarHBondContact CB-OD1 3.41Å; T32-D300 WeakPolarHBondContact CG2-OD1 3.42Å; T32-D300 PolarHBondContact N-OD1 3.48Å; T32-D300 PolarHBondContact OG1-OD1 3.28Å
33Q95.6Very high91.4Very high31 Ų3150 Ų5015%0.14525%0.253CS..PPolyproline II helixtrans-86.2169.9174.1-67178.2-86.800110.1L24 A26 A31 C296 V297L24-Q33 WeakPolarHBondContact O-CB 3.41Å; L24-Q33 WeakPolarHBondContact O-CG 3.43Å; L24-Q33 PolarHBondContact O-NE2 2.77Å; A26-Q33 HydrophobicContact CB-CG 3.7Å; A31-Q33 PolarHBondContact O-N 2.96Å; Q33-C296 WeakPolarHBondContact CB-O 3.49Å; Q33-C296 PolarHBondContact N-O 3.08Å; Q33-V297 HydrophobicContact CB-CG2 4.42Å
34K96.4Very high91.4Very high89 Ų8949.7 Ų49.739%0.38725%0.251SS..EExtended strand (participates in β ladder)trans-111136.3175.6-70.2173.9174.8-171.40109L24 F47 V57L24-K34 HydrophobicContact CB-CB 4.35Å; L24-K34 HydrophobicContact CD1-CB 4.03Å; L24-K34 PolarHBondContact N-O 3.1Å; K34-F47 CarbonylContact C-O 3.58Å; K34-F47 VanDerWaalsContact CA-O 3.31Å; K34-F47 WeakPolarHBondContact CA-O 3.34Å; K34-F47 WeakPolarHBondContact CB-O 3.31Å; K34-V57 HydrophobicContact CD-CG2 4Å
35V98Very high91.5Very high0 Ų050.5 Ų50.50%026%0.255CS..EExtended strand (participates in β ladder)trans-88.1137.4175.5-175.20000108.3M21 L23 C46 F47 V297 V306 V314M21-V35 HydrophobicContact CG-CG1 3.69Å; M21-V35 HydrophobicContact SD-CG1 4.02Å; L23-V35 HydrophobicContact CD2-CB 4.3Å; L23-V35 HydrophobicContact CD2-CG1 4.48Å; L23-V35 HydrophobicContact CD2-CG2 3.66Å; V35-C46 CarbonylContact O-C 3.57Å; V35-C46 VanDerWaalsContact O-CA 3.24Å; V35-C46 WeakPolarHBondContact O-CA 3.34Å; V35-F47 HydrophobicContact CB-CD1 3.91Å; V35-F47 HydrophobicContact CB-CE1 3.43Å; V35-F47 VanDerWaalsContact CB-CE1 3.43Å; V35-F47 HydrophobicContact CB-CE2 4.17Å; V35-F47 HydrophobicContact CB-CZ 3.58Å; V35-F47 HydrophobicContact CG1-CD1 4.37Å; V35-F47 HydrophobicContact CG1-CE1 3.6Å; V35-F47 HydrophobicContact CG1-CZ 3.96Å; V35-F47 HydrophobicContact CG2-CE1 4.07Å; V35-F47 HydrophobicContact CG2-CE2 4.02Å; V35-F47 HydrophobicContact CG2-CZ 3.65Å; V35-F47 PolarHBondContact N-O 2.82Å; V35-F47 PolarHBondContact O-N 2.86Å; V35-V297 HydrophobicContact CG2-CB 4.45Å; V35-V297 HydrophobicContact CG2-CG1 3.74Å; V35-V297 HydrophobicContact CG2-CG2 3.9Å; V35-V306 HydrophobicContact CG2-CG1 4.41Å; V35-V314 HydrophobicContact CG1-CG1 4.27Å
36V98.4Very high91.8Very high0 Ų048.2 Ų48.20%024%0.24CC..EExtended strand (participates in β ladder)trans-121.5131.2169.7-173.90000107.6M21 K22 L24 V44 M45 C46 L69 I82M21-V36 CarbonylContact C-O 3.55Å; M21-V36 VanDerWaalsContact CA-O 3.31Å; M21-V36 WeakPolarHBondContact CA-O 3.3Å; K22-V36 PolarHBondContact N-O 3.05Å; K22-V36 PolarHBondContact O-N 2.89Å; L24-V36 HydrophobicContact CD1-CG2 3.69Å; L24-V36 HydrophobicContact CD2-CG2 4.25Å; L24-V36 HydrophobicContact CG-CG2 3.68Å; V36-V44 HydrophobicContact CG1-CG1 3.93Å; V36-M45 WeakPolarHBondContact CA-O 3.42Å; V36-C46 HydrophobicContact CG2-CB 4.01Å; V36-L69 HydrophobicContact CG1-CD1 3.85Å; V36-L69 HydrophobicContact CG1-CD2 4.5Å; V36-I82 HydrophobicContact CB-CD1 4.45Å; V36-I82 HydrophobicContact CG1-CD1 3.92Å; V36-I82 HydrophobicContact CG1-CG1 4.28Å; V36-I82 HydrophobicContact CG1-CG2 3.84Å; V36-I82 HydrophobicContact CG2-CD1 3.73Å; V36-I82 HydrophobicContact CG2-CG1 4.23Å
37I98.6Very high92.4Very high1 Ų146.3 Ų46.31%0.00522%0.224CC..EExtended strand (participates in β ladder)trans-142.8143-176.4-169.1161.6000110.7V13 T16 T20 M21 V44 M45 S308 V314V13-I37 HydrophobicContact CG1-CG2 3.7Å; V13-I37 HydrophobicContact CG2-CD1 3.6Å; V13-I37 HydrophobicContact CG2-CG1 4.03Å; V13-I37 HydrophobicContact CG2-CG2 4.26Å; T16-I37 HydrophobicContact CG2-CD1 3.98Å; T16-I37 HydrophobicContact CG2-CG1 4.2Å; T20-I37 WeakPolarHBondContact O-CA 3.35Å; M21-I37 HydrophobicContact CB-CB 4.47Å; M21-I37 HydrophobicContact CB-CD1 4.15Å; M21-I37 HydrophobicContact CB-CG1 4.18Å; M21-I37 HydrophobicContact CG-CB 4.43Å; M21-I37 HydrophobicContact CG-CD1 4.29Å; I37-V44 WeakPolarHBondContact O-CA 3.24Å; I37-M45 HydrophobicContact CG2-CB 4.31Å; I37-M45 PolarHBondContact N-O 2.78Å; I37-M45 PolarHBondContact O-N 2.79Å; I37-S308 WeakPolarHBondContact CD1-OG 3.38Å; I37-V314 HydrophobicContact CD1-CG2 3.54Å
38G98.3Very high93.3Very high0 Ų041.5 Ų41.50%019%0.192CC..EExtended strand (participates in β ladder)trans-121.1139.1176.200000112T20 V43T20-G38 PolarHBondContact O-N 2.79Å; T20-G38 VanDerWaalsContact O-N 3.09Å; T20-G38 PolarHBondContact OG1-O 2.9Å; G38-V43 WeakPolarHBondContact CA-O 3.44Å
39D97.6Very high94Very high11 Ų1133 Ų336%0.05916%0.161CC..EExtended strand (participates in β ladder)trans-113.8177.4-17766.127.8000114.2V15 D41 G42 V43 I66V15-D39 CarbonylContact O-C 3.55Å; V15-D39 WeakPolarHBondContact O-CA 3.21Å; D39-D41 PolarHBondContact O-N 2.9Å; D39-D41 WeakPolarHBondContact OD1-CA 3.49Å; D39-D41 WeakPolarHBondContact OD1-CB 3.39Å; D39-D41 PolarHBondContact OD1-N 2.92Å; D39-G42 PolarHBondContact O-N 2.95Å; D39-G42 PolarHBondContact OD1-N 2.98Å; D39-V43 PolarHBondContact N-O 3.03Å; D39-V43 WeakPolarHBondContact OD1-CB 3.37Å; D39-V43 PolarHBondContact OD1-N 2.86Å; D39-I66 WeakPolarHBondContact O-CB 3.49Å; D39-I66 WeakPolarHBondContact O-CG1 3.36Å; D39-I66 PolarHBondContact O-N 3.39Å
40H97.1Very high94.5Very high43 Ų4332.9 Ų32.920%0.19916%0.159CC..THydrogen-bonded Turntrans-72.5-14.6179-72.4-178.1000114.1V15 T16 S17 G42 K65V15-H40 HydrophobicContact CB-CB 4.28Å; V15-H40 WeakPolarHBondContact CG1-CE1 3.49Å; V15-H40 VanDerWaalsContact CG1-ND1 3.28Å; V15-H40 WeakPolarHBondContact CG1-ND1 3.4Å; V15-H40 WeakPolarHBondContact O-CB 3.46Å; V15-H40 PolarHBondContact O-CD2 3.16Å; V15-H40 VanDerWaalsContact O-CD2 3.23Å; V15-H40 VanDerWaalsContact O-CG 3.25Å; V15-H40 PolarHBondContact O-N 3.04Å; T16-H40 PolarHBondContact O-NE2 2.94Å; S17-H40 PolarHBondContact N-NE2 2.84Å; S17-H40 PolarHBondContact OG-CD2 3.29Å; S17-H40 PolarHBondContact OG-NE2 3.33Å; H40-G42 PolarHBondContact O-N 2.74Å; H40-K65 HydrophobicContact CB-CD 4.44Å; H40-K65 HydrophobicContact CB-CG 4.31Å; H40-K65 VanDerWaalsContact CD2-CE 3.41Å; H40-K65 WeakPolarHBondContact CD2-CE 3.27Å; H40-K65 PolarHBondContact CE1-NZ 3.42Å; H40-K65 VanDerWaalsContact CE1-NZ 3.27Å; H40-K65 WeakPolarHBondContact NE2-CE 3.22Å; H40-K65 PolarHBondContact NE2-NZ 2.59Å; H40-K65 WeakPolarHBondContact O-CA 3.24Å
41D96.1Very high94.9Very high103 Ų10337.7 Ų37.755%0.55118%0.183SC*.THydrogen-bonded Turntrans-84.94.8172-62.6-37.9000111.5D39 V43 P62 G63D39-D41 PolarHBondContact O-N 2.9Å; D39-D41 WeakPolarHBondContact OD1-CA 3.49Å; D39-D41 WeakPolarHBondContact OD1-CB 3.39Å; D39-D41 PolarHBondContact OD1-N 2.92Å; D41-V43 HydrophobicContact CB-CG2 4.34Å; D41-V43 PolarHBondContact O-N 2.83Å; D41-P62 CarbonylContact O-C 3.57Å; D41-P62 VanDerWaalsContact O-CA 3.25Å; D41-P62 WeakPolarHBondContact O-CA 3.25Å; D41-P62 WeakPolarHBondContact O-CB 3.48Å; D41-G63 CarbonylContact C-O 3.6Å; D41-G63 PolarHBondContact O-N 3.37Å; D41-G63 VanDerWaalsContact O-O 3.06Å
42G96.6Very high94.4Very high0 Ų039.9 Ų39.90%021%0.207CC..SBendtrans75.213.5178.200000113.8D39 H40 P64D39-G42 PolarHBondContact O-N 2.95Å; D39-G42 PolarHBondContact OD1-N 2.98Å; H40-G42 PolarHBondContact O-N 2.74Å; G42-P64 WeakPolarHBondContact CA-O 3.17Å
43V97.8Very high94.1Very high10 Ų1044.8 Ų44.86%0.06123%0.227CC..  trans-88.1129.4179.4178.70000109.1G38 D39 D41 K59 P62G38-V43 WeakPolarHBondContact CA-O 3.44Å; D39-V43 PolarHBondContact N-O 3.03Å; D39-V43 WeakPolarHBondContact OD1-CB 3.37Å; D39-V43 PolarHBondContact OD1-N 2.86Å; D41-V43 HydrophobicContact CB-CG2 4.34Å; D41-V43 PolarHBondContact O-N 2.83Å; V43-K59 HydrophobicContact CG1-CD 4.17Å; V43-K59 VanDerWaalsContact CG1-CE 3.44Å; V43-K59 HydrophobicContact CG1-CG 3.59Å; V43-P62 HydrophobicContact CG2-CB 4.1Å; V43-P62 HydrophobicContact CG2-CG 3.91Å
44V98Very high93.9Very high0 Ų045 Ų450%023%0.233CC..EExtended strand (participates in β ladder)trans-106.7123.5169.3-176.40000108.7V36 I37 F58 K59 T60 I66 L69 I84V36-V44 HydrophobicContact CG1-CG1 3.93Å; I37-V44 WeakPolarHBondContact O-CA 3.24Å; V44-F58 HydrophobicContact CG1-CE2 4.23Å; V44-F58 HydrophobicContact CG1-CZ 4.48Å; V44-K59 WeakPolarHBondContact O-CA 3.47Å; V44-T60 HydrophobicContact CB-CG2 4.09Å; V44-T60 PolarHBondContact N-OG1 3.21Å; V44-T60 PolarHBondContact O-N 2.84Å; V44-I66 HydrophobicContact CG2-CD1 4.31Å; V44-I66 HydrophobicContact CG2-CG1 4.26Å; V44-L69 HydrophobicContact CG1-CD1 4.4Å; V44-I84 HydrophobicContact CG2-CD1 3.54Å; V44-I84 HydrophobicContact CG2-CG2 3.9Å
45M97.8Very high93.6Very high27 Ų2742.3 Ų42.313%0.13323%0.231CC..EExtended strand (participates in β ladder)trans-118132.8179-175.5171.1171.300109.6L11 V13 V36 I37 F47 A56L11-M45 HydrophobicContact CD1-CE 4.48Å; L11-M45 HydrophobicContact CD1-SD 4.36Å; L11-M45 HydrophobicContact CD2-CE 3.68Å; L11-M45 HydrophobicContact CD2-SD 4.38Å; V13-M45 HydrophobicContact CG1-SD 4.31Å; V36-M45 WeakPolarHBondContact CA-O 3.42Å; I37-M45 HydrophobicContact CG2-CB 4.31Å; I37-M45 PolarHBondContact N-O 2.78Å; I37-M45 PolarHBondContact O-N 2.79Å; M45-F47 HydrophobicContact CE-CB 4.15Å; M45-A56 HydrophobicContact CE-CB 3.97Å
46C98Very high93.4Very high0 Ų045.6 Ų45.60%026%0.258CS..EExtended strand (participates in β ladder)trans-113.3132165.3178.50000108.7V35 V36 V57 F58V35-C46 CarbonylContact O-C 3.57Å; V35-C46 VanDerWaalsContact O-CA 3.24Å; V35-C46 WeakPolarHBondContact O-CA 3.34Å; V36-C46 HydrophobicContact CG2-CB 4.01Å; C46-V57 HydrophobicContact CB-CB 4.28Å; C46-V57 WeakPolarHBondContact O-CB 3.23Å; C46-V57 PolarHBondContact O-N 2.89Å; C46-F58 HydrophobicContact CB-CD1 3.54Å; C46-F58 HydrophobicContact CB-CE1 3.23Å; C46-F58 HydrophobicContact CB-CE2 4.5Å; C46-F58 HydrophobicContact CB-CG 4.31Å; C46-F58 HydrophobicContact CB-CZ 3.77Å; C46-F58 PolarHBondContact N-O 3.08Å; C46-F58 PolarHBondContact O-N 2.96Å
47F97.2Very high93.3Very high0 Ų048.4 Ų48.40%028%0.275CS..EExtended strand (participates in β ladder)trans-135.8162.9176.173.8-88.9000111.4L11 K34 V35 M45 M49 A54 G55 V314L11-F47 HydrophobicContact CD2-CB 4.12Å; L11-F47 HydrophobicContact CD2-CD1 3.23Å; L11-F47 HydrophobicContact CD2-CD2 3.81Å; L11-F47 HydrophobicContact CD2-CE1 3.33Å; L11-F47 HydrophobicContact CD2-CE2 3.93Å; L11-F47 HydrophobicContact CD2-CG 3.45Å; L11-F47 VanDerWaalsContact CD2-CG 3.45Å; L11-F47 HydrophobicContact CD2-CZ 3.69Å; L11-F47 HydrophobicContact CG-CD1 4.31Å; L11-F47 HydrophobicContact CG-CE1 3.96Å; L11-F47 HydrophobicContact CG-CZ 4.16Å; K34-F47 CarbonylContact C-O 3.58Å; K34-F47 VanDerWaalsContact CA-O 3.31Å; K34-F47 WeakPolarHBondContact CA-O 3.34Å; K34-F47 WeakPolarHBondContact CB-O 3.31Å; V35-F47 HydrophobicContact CB-CD1 3.91Å; V35-F47 HydrophobicContact CB-CE1 3.43Å; V35-F47 VanDerWaalsContact CB-CE1 3.43Å; V35-F47 HydrophobicContact CB-CE2 4.17Å; V35-F47 HydrophobicContact CB-CZ 3.58Å; V35-F47 HydrophobicContact CG1-CD1 4.37Å; V35-F47 HydrophobicContact CG1-CE1 3.6Å; V35-F47 HydrophobicContact CG1-CZ 3.96Å; V35-F47 HydrophobicContact CG2-CE1 4.07Å; V35-F47 HydrophobicContact CG2-CE2 4.02Å; V35-F47 HydrophobicContact CG2-CZ 3.65Å; V35-F47 PolarHBondContact N-O 2.82Å; V35-F47 PolarHBondContact O-N 2.86Å; M45-F47 HydrophobicContact CE-CB 4.15Å; F47-M49 HydrophobicContact CE2-SD 4.38Å; F47-A54 HydrophobicContact CD2-CB 3.78Å; F47-A54 HydrophobicContact CE2-CB 4.11Å; F47-G55 VanDerWaalsContact CA-O 3.28Å; F47-G55 WeakPolarHBondContact CA-O 3.42Å; F47-G55 WeakPolarHBondContact CB-O 2.98Å; F47-V314 HydrophobicContact CE1-CG1 4.42Å; F47-V314 HydrophobicContact CE1-CG2 4.45Å; F47-V314 HydrophobicContact CZ-CB 4.34Å; F47-V314 HydrophobicContact CZ-CG1 3.99Å
48G94.8Very high93.2Very high10 Ų1049.5 Ų49.510%0.10328%0.28CS..EExtended strand (participates in β ladder)trans-144.2156.2169.200000110G55G48-G55 PolarHBondContact N-O 3.08Å; G48-G55 PolarHBondContact O-N 3.05Å
49M92.6Very high93.2Very high22 Ų2256.3 Ų56.311%0.10831%0.309CS..EExtended strand (participates in β ladder)trans-80.4133.8-178.8-60.7-61.3-7100110.5Y10 F47 G52 E53 A54 V297Y10-M49 HydrophobicContact CD1-CE 3.66Å; Y10-M49 HydrophobicContact CD1-CG 4.29Å; Y10-M49 HydrophobicContact CD1-SD 3.65Å; Y10-M49 HydrophobicContact CE1-CE 4.03Å; Y10-M49 HydrophobicContact CE1-CG 4.28Å; Y10-M49 HydrophobicContact CE1-SD 4.2Å; Y10-M49 HydrophobicContact CG-SD 4.31Å; F47-M49 HydrophobicContact CE2-SD 4.38Å; M49-G52 VanDerWaalsContact CE-C 3.47Å; M49-G52 VanDerWaalsContact CE-O 3.23Å; M49-G52 WeakPolarHBondContact CE-O 3.42Å; M49-E53 WeakPolarHBondContact CA-O 3.14Å; M49-A54 HydrophobicContact SD-CB 3.82Å; M49-V297 VanDerWaalsContact CB-O 3.26Å; M49-V297 WeakPolarHBondContact CB-O 3.45Å; M49-V297 HydrophobicContact CG-CG1 3.83Å; M49-V297 WeakPolarHBondContact CG-O 3.4Å
50K84.4Confident93.2Very high165 Ų16557 Ų5772%0.71731%0.314SS*.EExtended strand (participates in β ladder)trans-136.7119.6170.5-71.1-175.4179.9177.90108.2G52 E53K50-G52 PolarHBondContact O-N 3.36Å; K50-E53 PolarHBondContact N-O 2.99Å; K50-E53 PolarHBondContact O-N 3.24Å; K50-E53 VanDerWaalsContact O-N 3.11Å
51K79.8Confident93.1Very high214 Ų21462.1 Ų62.193%0.9334%0.342SS*.THydrogen-bonded Turntrans53.339.6-178.9-56-178.6176.4-177.20113.2E53K51-E53 VanDerWaalsContact C-N 3.27Å; K51-E53 PolarHBondContact O-N 3.33Å
52G78.1Confident93.2Very high63 Ų6361.9 Ų61.965%0.64935%0.346SS*.THydrogen-bonded Turntrans80-1.4179.800000115.5M49 K50M49-G52 VanDerWaalsContact CE-C 3.47Å; M49-G52 VanDerWaalsContact CE-O 3.23Å; M49-G52 WeakPolarHBondContact CE-O 3.42Å; K50-G52 PolarHBondContact O-N 3.36Å
53E85.1Confident93.1Very high152 Ų15263.5 Ų63.571%0.7136%0.363SS*.EExtended strand (participates in β ladder)trans-110.5141.2177.4-66.5-179.7174.900112M49 K50 K51 G55M49-E53 WeakPolarHBondContact CA-O 3.14Å; K50-E53 PolarHBondContact N-O 2.99Å; K50-E53 PolarHBondContact O-N 3.24Å; K50-E53 VanDerWaalsContact O-N 3.11Å; K51-E53 VanDerWaalsContact C-N 3.27Å; K51-E53 PolarHBondContact O-N 3.33Å; E53-G55 PolarHBondContact O-N 3.43Å
54A90.4Very high93Very high35 Ų3566.1 Ų66.129%0.28938%0.38SS..EExtended strand (participates in β ladder)trans-76.9105.9176.100000110.6L11 F47 M49L11-A54 HydrophobicContact CB-CB 4.23Å; L11-A54 HydrophobicContact CD2-CB 4.03Å; F47-A54 HydrophobicContact CD2-CB 3.78Å; F47-A54 HydrophobicContact CE2-CB 4.11Å; M49-A54 HydrophobicContact SD-CB 3.82Å
55G91.3Very high93Very high33 Ų3371 Ų7134%0.3440%0.402SS..EExtended strand (participates in β ladder)trans-95.8123.5177.300000112.1F47 G48 E53 V57F47-G55 VanDerWaalsContact CA-O 3.28Å; F47-G55 WeakPolarHBondContact CA-O 3.42Å; F47-G55 WeakPolarHBondContact CB-O 2.98Å; G48-G55 PolarHBondContact N-O 3.08Å; G48-G55 PolarHBondContact O-N 3.05Å; E53-G55 PolarHBondContact O-N 3.43Å; G55-V57 PolarHBondContact O-N 3.49Å
56A93.9Very high93Very high68 Ų6869.7 Ų69.756%0.56240%0.395SS*.EExtended strand (participates in β ladder)trans-62.9127.8173.900000111.1M45M45-A56 HydrophobicContact CE-CB 3.97Å
57V95.4Very high93Very high59 Ų5970.5 Ų70.536%0.35840%0.402SS..EExtended strand (participates in β ladder)trans-87.2-46.9171.5178.80000109.7K34 C46 G55K34-V57 HydrophobicContact CD-CG2 4Å; C46-V57 HydrophobicContact CB-CB 4.28Å; C46-V57 WeakPolarHBondContact O-CB 3.23Å; C46-V57 PolarHBondContact O-N 2.89Å; G55-V57 PolarHBondContact O-N 3.49Å
58F97.2Very high93Very high25 Ų2570.7 Ų70.711%0.1140%0.403CS..EExtended strand (participates in β ladder)trans-154.2158.2167.872.7-93.1000109.7V44 C46 T60 I82 G97V44-F58 HydrophobicContact CG1-CE2 4.23Å; V44-F58 HydrophobicContact CG1-CZ 4.48Å; C46-F58 HydrophobicContact CB-CD1 3.54Å; C46-F58 HydrophobicContact CB-CE1 3.23Å; C46-F58 HydrophobicContact CB-CE2 4.5Å; C46-F58 HydrophobicContact CB-CG 4.31Å; C46-F58 HydrophobicContact CB-CZ 3.77Å; C46-F58 PolarHBondContact N-O 3.08Å; C46-F58 PolarHBondContact O-N 2.96Å; F58-T60 HydrophobicContact CD2-CG2 4.29Å; F58-T60 HydrophobicContact CE2-CG2 4.16Å; F58-I82 HydrophobicContact CE1-CD1 4.07Å; F58-I82 HydrophobicContact CZ-CD1 3.88Å; F58-G97 VanDerWaalsContact CD1-CA 3.46Å; F58-G97 VanDerWaalsContact CG-CA 3.43Å
59K97.3Very high93.2Very high142 Ų14270.2 Ų70.262%0.61740%0.398SS*.EExtended strand (participates in β ladder)trans-141.2127.5172.9-172.7175.4-176.71750107.9V43 V44V43-K59 HydrophobicContact CG1-CD 4.17Å; V43-K59 VanDerWaalsContact CG1-CE 3.44Å; V43-K59 HydrophobicContact CG1-CG 3.59Å; V44-K59 WeakPolarHBondContact O-CA 3.47Å
60T97.4Very high93.4Very high26 Ų2670.2 Ų70.216%0.1640%0.397CS..PPolyproline II helixtrans-80.1168.3178.365.20000111.3V44 F58 F93V44-T60 HydrophobicContact CB-CG2 4.09Å; V44-T60 PolarHBondContact N-OG1 3.21Å; V44-T60 PolarHBondContact O-N 2.84Å; F58-T60 HydrophobicContact CD2-CG2 4.29Å; F58-T60 HydrophobicContact CE2-CG2 4.16Å; T60-F93 HydrophobicContact CG2-CD1 4.42Å; T60-F93 HydrophobicContact CG2-CE1 3.87Å; T60-F93 HydrophobicContact CG2-CZ 4.18Å
61L96.7Very high94Very high150 Ų15063.1 Ų63.179%0.78537%0.367SS*.PPolyproline II helixtrans-69.9153.8168.1-62.7175.9000110.3
62P96.8Very high94.6Very high98 Ų9853 Ų5364%0.63632%0.323SS*.PPolyproline II helixtrans-56.6155.5171.9-24.334.4000112.8D41 V43D41-P62 CarbonylContact O-C 3.57Å; D41-P62 VanDerWaalsContact O-CA 3.25Å; D41-P62 WeakPolarHBondContact O-CA 3.25Å; D41-P62 WeakPolarHBondContact O-CB 3.48Å; V43-P62 HydrophobicContact CG2-CB 4.1Å; V43-P62 HydrophobicContact CG2-CG 3.91Å
63G95.8Very high95.2Very high34 Ų3450.8 Ų50.835%0.35130%0.301SS..  trans-167.6-157.3-178.600000112D41D41-G63 CarbonylContact C-O 3.6Å; D41-G63 PolarHBondContact O-N 3.37Å; D41-G63 VanDerWaalsContact O-O 3.06Å
64P95.9Very high95.3Very high66 Ų6648.7 Ų48.743%0.42930%0.298SS..SBendtrans-64.6148.3174.2-16.930.1000111.4G42 I66 A86 A87G42-P64 WeakPolarHBondContact CA-O 3.17Å; P64-I66 PolarHBondContact O-N 3.44Å; P64-A86 HydrophobicContact CB-CB 4.27Å; P64-A87 HydrophobicContact CB-CB 4.28Å
65K96.4Very high94.9Very high102 Ų10250.3 Ų50.344%0.44330%0.301SS..  trans-43.3127.3174.9164.2172.3172.41630112.1S17 H40 A67S17-K65 WeakPolarHBondContact OG-CE 3.23Å; S17-K65 PolarHBondContact OG-NZ 2.87Å; H40-K65 HydrophobicContact CB-CD 4.44Å; H40-K65 HydrophobicContact CB-CG 4.31Å; H40-K65 VanDerWaalsContact CD2-CE 3.41Å; H40-K65 WeakPolarHBondContact CD2-CE 3.27Å; H40-K65 PolarHBondContact CE1-NZ 3.42Å; H40-K65 VanDerWaalsContact CE1-NZ 3.27Å; H40-K65 WeakPolarHBondContact NE2-CE 3.22Å; H40-K65 PolarHBondContact NE2-NZ 2.59Å; H40-K65 WeakPolarHBondContact O-CA 3.24Å; K65-A67 PolarHBondContact O-N 2.98Å
66I98.3Very high94.5Very high0 Ų055.2 Ų55.20%032%0.32CS..EExtended strand (participates in β ladder)trans-75.5116.8172.3-53.1-47.6000108.9T20 D39 V44 P64 I84 A86T20-I66 HydrophobicContact CG2-CG2 4.29Å; D39-I66 WeakPolarHBondContact O-CB 3.49Å; D39-I66 WeakPolarHBondContact O-CG1 3.36Å; D39-I66 PolarHBondContact O-N 3.39Å; V44-I66 HydrophobicContact CG2-CD1 4.31Å; V44-I66 HydrophobicContact CG2-CG1 4.26Å; P64-I66 PolarHBondContact O-N 3.44Å; I66-I84 HydrophobicContact CD1-CD1 3.78Å; I66-I84 HydrophobicContact CD1-CG1 4.44Å; I66-I84 HydrophobicContact CG2-CB 4.23Å; I66-I84 HydrophobicContact CG2-CG2 4.46Å; I66-A86 HydrophobicContact CD1-CB 3.83Å
67A97.6Very high94.1Very high17 Ų1755.1 Ų55.114%0.1431%0.313CS..EExtended strand (participates in β ladder)trans-91.2-34.4-178.500000112.5K65 A85 I111K65-A67 PolarHBondContact O-N 2.98Å; A67-A85 PolarHBondContact N-O 3.01Å; A67-I111 VanDerWaalsContact CB-O 3.26Å; A67-I111 WeakPolarHBondContact CB-O 3.12Å
68R98.2Very high93.7Very high4 Ų456.7 Ų56.72%0.01532%0.324CS..EExtended strand (participates in β ladder)trans-150147179.7-160.36967.617215.8110.9Q18 I84 A85 K112 M114Q18-R68 PolarHBondContact O-NH1 3.22Å; Q18-R68 VanDerWaalsContact OE1-NH1 3.13Å; R68-I84 WeakPolarHBondContact O-CA 3.38Å; R68-A85 HydrophobicContact CB-CB 4.29Å; R68-A85 PolarHBondContact O-N 3.21Å; R68-K112 PolarHBondContact NE-O 3.45Å; R68-K112 PolarHBondContact NH2-O 2.84Å; R68-M114 HydrophobicContact CB-CB 4.4Å; R68-M114 HydrophobicContact CG-CB 4.18Å
69L98.3Very high93.4Very high0 Ų060 Ų600%034%0.34CS..EExtended strand (participates in β ladder)trans-132.2125.9172.9-171.1152.3000109.6K19 K22 V36 V44 I82 F83 I84K19-L69 PolarHBondContact O-N 2.63Å; K22-L69 HydrophobicContact CB-CD2 3.74Å; K22-L69 VanDerWaalsContact CE-O 3.25Å; K22-L69 WeakPolarHBondContact CE-O 3.4Å; K22-L69 HydrophobicContact CG-CD2 3.4Å; V36-L69 HydrophobicContact CG1-CD1 3.85Å; V36-L69 HydrophobicContact CG1-CD2 4.5Å; V44-L69 HydrophobicContact CG1-CD1 4.4Å; L69-I82 HydrophobicContact CD1-CG2 4.18Å; L69-I82 HydrophobicContact CD2-CG2 4.29Å; L69-I82 HydrophobicContact CG-CG2 4.21Å; L69-F83 WeakPolarHBondContact CA-O 3.07Å; L69-I84 HydrophobicContact CB-CG2 4.45Å; L69-I84 HydrophobicContact CD1-CG2 3.87Å; L69-I84 HydrophobicContact CG-CG2 3.99Å
70E97.9Very high93.2Very high22 Ų2256.4 Ų56.410%0.10333%0.325CS..EExtended strand (participates in β ladder)trans-132.1152.2176.3-74.8-62.2158.600111.4K22 F83 M114 I116K22-E70 VanDerWaalsContact CE-CD 3.5Å; K22-E70 WeakPolarHBondContact CE-OE1 3.37Å; K22-E70 WeakPolarHBondContact CE-OE2 3.45Å; K22-E70 IonicContact NZ-OE1 2.64Å; K22-E70 PolarHBondContact NZ-OE1 2.88Å; K22-E70 IonicContact NZ-OE2 3.43Å; K22-E70 PolarHBondContact NZ-OE2 3.25Å; E70-F83 PolarHBondContact N-O 2.92Å; E70-F83 PolarHBondContact O-N 3.08Å; E70-M114 HydrophobicContact CB-CE 4.05Å; E70-M114 HydrophobicContact CG-CE 4.46Å; E70-I116 HydrophobicContact CB-CD1 4.32Å
71L96.6Very high93.2Very high16 Ų1659.1 Ų59.18%0.08434%0.335CS..EExtended strand (participates in β ladder)trans-92.8140.3170.6-59.1-176.5000109.1K22 L23 L24 Q79 K81 I82K22-L71 HydrophobicContact CB-CD1 3.95Å; K22-L71 HydrophobicContact CB-CD2 4.13Å; K22-L71 HydrophobicContact CB-CG 3.78Å; K22-L71 HydrophobicContact CG-CG 4.08Å; L23-L71 WeakPolarHBondContact O-CD1 3.23Å; L24-L71 HydrophobicContact CD2-CD1 4.34Å; L24-L71 HydrophobicContact CD2-CD2 3.92Å; L71-Q79 HydrophobicContact CB-CB 4.14Å; L71-K81 CarbonylContact C-O 3.58Å; L71-K81 WeakPolarHBondContact CA-O 3.34Å; L71-I82 HydrophobicContact CD2-CB 4.46Å; L71-I82 HydrophobicContact CD2-CG1 3.88Å
72G92.9Very high93.3Very high1 Ų152 Ų521%0.0130%0.297CS..EExtended strand (participates in β ladder)trans-139173.8177.500000111.6Q79 E80 K81G72-Q79 CarbonylContact O-C 3.6Å; G72-Q79 WeakPolarHBondContact O-CA 3.44Å; G72-E80 PolarHBondContact O-N 3.26Å; G72-K81 PolarHBondContact N-O 3.44Å; G72-K81 VanDerWaalsContact O-CB 3.29Å; G72-K81 WeakPolarHBondContact O-CB 3.22Å; G72-K81 PolarHBondContact O-N 3.47Å
73G89.9Confident93.4Very high17 Ų1748.4 Ų48.418%0.17527%0.272CS..  trans176.4175.6-177.400000110.4G118G73-G118 WeakPolarHBondContact O-CA 3.31Å
74V86.4Confident93.5Very high108 Ų10846.8 Ų46.866%0.65526%0.255SS*.SBendtrans-63.6142.3170.4-179.90000108.1N76 T77V74-N76 PolarHBondContact O-N 3.11Å; V74-T77 HydrophobicContact CB-CG2 4.04Å; V74-T77 HydrophobicContact CG1-CG2 4.36Å; V74-T77 PolarHBondContact N-OG1 2.67Å; V74-T77 WeakPolarHBondContact O-CB 3.36Å; V74-T77 PolarHBondContact O-N 2.94Å; V74-T77 PolarHBondContact O-OG1 3.43Å
75L82.9Confident93.6Very high68 Ų6843.7 Ų43.736%0.35624%0.235SC..THydrogen-bonded Turntrans-49.3141.7176.7-64.3175.1000110.9T77 E156L75-T77 PolarHBondContact O-N 3.1Å; L75-T77 VanDerWaalsContact O-N 3.13Å; L75-E156 VanDerWaalsContact CA-OE1 3.29Å; L75-E156 WeakPolarHBondContact CA-OE1 3.26Å; L75-E156 HydrophobicContact CB-CG 4.24Å; L75-E156 VanDerWaalsContact CB-OE1 3.32Å; L75-E156 WeakPolarHBondContact CB-OE1 3.32Å; L75-E156 HydrophobicContact CD2-CG 3.97Å; L75-E156 VanDerWaalsContact CD2-OE1 3.28Å; L75-E156 WeakPolarHBondContact CD2-OE1 3.39Å; L75-E156 HydrophobicContact CG-CG 4.45Å
76N81.9Confident93.5Very high137 Ų13738.9 Ų38.973%0.73321%0.214SC*.THydrogen-bonded Turntrans58.414.8-175.6-54.4-64.6000116.1V74 E156V74-N76 PolarHBondContact O-N 3.11Å; N76-E156 PolarHBondContact N-OE1 2.73Å
77T87.1Confident93.3Very high66 Ų6641 Ų4141%0.40523%0.232SC..SBendtrans-112.7155.1171.671.20000111.1V74 L75 Q79V74-T77 HydrophobicContact CB-CG2 4.04Å; V74-T77 HydrophobicContact CG1-CG2 4.36Å; V74-T77 PolarHBondContact N-OG1 2.67Å; V74-T77 WeakPolarHBondContact O-CB 3.36Å; V74-T77 PolarHBondContact O-N 2.94Å; V74-T77 PolarHBondContact O-OG1 3.43Å; L75-T77 PolarHBondContact O-N 3.1Å; L75-T77 VanDerWaalsContact O-N 3.13Å; T77-Q79 PolarHBondContact O-N 2.98Å
78P86.3Confident93.2Very high92 Ų9241.6 Ų41.660%0.59724%0.235SC*.  trans-54.6125173.7-25.734.8000111.4P25 E80P25-P78 HydrophobicContact CB-CB 4.46Å; P25-P78 HydrophobicContact CG-CB 4.46Å; P78-E80 HydrophobicContact CB-CG 4.28Å; P78-E80 PolarHBondContact O-N 3.4Å
79Q91.4Very high93.1Very high95 Ų9543.2 Ų43.244%0.44424%0.243SC..  trans-75.691.2-178.5-64.9177.2-6.600110.1P25 L71 G72 T77P25-Q79 VanDerWaalsContact CD-O 3.29Å; P25-Q79 WeakPolarHBondContact CD-O 3.24Å; P25-Q79 WeakPolarHBondContact CG-O 3.18Å; L71-Q79 HydrophobicContact CB-CB 4.14Å; G72-Q79 CarbonylContact O-C 3.6Å; G72-Q79 WeakPolarHBondContact O-CA 3.44Å; T77-Q79 PolarHBondContact O-N 2.98Å
80E93.4Very high93Very high66 Ų6643.2 Ų43.231%0.30824%0.243SC..  trans-110-0.9-177-61.2-171144.300113.8P25 G72 P78 K95P25-E80 HydrophobicContact CG-CG 4.44Å; G72-E80 PolarHBondContact O-N 3.26Å; P78-E80 HydrophobicContact CB-CG 4.28Å; P78-E80 PolarHBondContact O-N 3.4Å; E80-K95 HydrophobicContact CB-CD 4.45Å; E80-K95 IonicContact OE1-NZ 3.69Å; E80-K95 PolarHBondContact OE1-NZ 3.12Å; E80-K95 WeakPolarHBondContact OE2-CD 3.29Å; E80-K95 WeakPolarHBondContact OE2-CE 3.29Å; E80-K95 IonicContact OE2-NZ 3.44Å; E80-K95 PolarHBondContact OE2-NZ 3.24Å
81K96.8Very high93Very high82 Ų8243.6 Ų43.636%0.35724%0.243SC..EExtended strand (participates in β ladder)trans-89.9129177.8-56-59.3-172.8168.90108.7L71 G72 F83 F100L71-K81 CarbonylContact C-O 3.58Å; L71-K81 WeakPolarHBondContact CA-O 3.34Å; G72-K81 PolarHBondContact N-O 3.44Å; G72-K81 VanDerWaalsContact O-CB 3.29Å; G72-K81 WeakPolarHBondContact O-CB 3.22Å; G72-K81 PolarHBondContact O-N 3.47Å; K81-F83 HydrophobicContact CB-CD2 4.2Å; K81-F83 HydrophobicContact CB-CE2 3.59Å; K81-F83 HydrophobicContact CB-CZ 4.39Å; K81-F100 HydrophobicContact CB-CE1 4.22Å; K81-F100 HydrophobicContact CB-CZ 4Å; K81-F100 HydrophobicContact CD-CE1 3.75Å; K81-F100 HydrophobicContact CD-CZ 3.85Å; K81-F100 HydrophobicContact CG-CE1 4.32Å; K81-F100 HydrophobicContact CG-CZ 4.02Å
82I98.3Very high93.1Very high0 Ų042.8 Ų42.80%024%0.239CC..EExtended strand (participates in β ladder)trans-96.8119.7-177.9-58.5156.9000106.9L24 V36 F58 L69 L71 I84 A92 F93L24-I82 HydrophobicContact CD2-CD1 4.31Å; L24-I82 HydrophobicContact CD2-CG1 4.05Å; V36-I82 HydrophobicContact CB-CD1 4.45Å; V36-I82 HydrophobicContact CG1-CD1 3.92Å; V36-I82 HydrophobicContact CG1-CG1 4.28Å; V36-I82 HydrophobicContact CG1-CG2 3.84Å; V36-I82 HydrophobicContact CG2-CD1 3.73Å; V36-I82 HydrophobicContact CG2-CG1 4.23Å; F58-I82 HydrophobicContact CE1-CD1 4.07Å; F58-I82 HydrophobicContact CZ-CD1 3.88Å; L69-I82 HydrophobicContact CD1-CG2 4.18Å; L69-I82 HydrophobicContact CD2-CG2 4.29Å; L69-I82 HydrophobicContact CG-CG2 4.21Å; L71-I82 HydrophobicContact CD2-CB 4.46Å; L71-I82 HydrophobicContact CD2-CG1 3.88Å; I82-I84 HydrophobicContact CG2-CG2 4.34Å; I82-A92 CarbonylContact O-C 3.4Å; I82-A92 VanDerWaalsContact O-CA 3.23Å; I82-A92 WeakPolarHBondContact O-CA 3.36Å; I82-F93 HydrophobicContact CB-CB 4.37Å; I82-F93 PolarHBondContact N-O 3.31Å; I82-F93 PolarHBondContact O-N 3.44Å
83F98.4Very high93.3Very high24 Ų2443.1 Ų43.111%0.10524%0.24CC..EExtended strand (participates in β ladder)trans-111.4135.6173.9-68-103.4000109.4L69 E70 K81 I90 R91 A92 F100 L101 M114 I116L69-F83 WeakPolarHBondContact CA-O 3.07Å; E70-F83 PolarHBondContact N-O 2.92Å; E70-F83 PolarHBondContact O-N 3.08Å; K81-F83 HydrophobicContact CB-CD2 4.2Å; K81-F83 HydrophobicContact CB-CE2 3.59Å; K81-F83 HydrophobicContact CB-CZ 4.39Å; F83-I90 HydrophobicContact CD1-CG2 4.12Å; F83-R91 WeakPolarHBondContact CA-O 3.12Å; F83-A92 HydrophobicContact CD1-CB 3.44Å; F83-A92 VanDerWaalsContact CD1-CB 3.44Å; F83-A92 HydrophobicContact CD2-CB 4.46Å; F83-A92 HydrophobicContact CE1-CB 3.51Å; F83-A92 HydrophobicContact CG-CB 3.95Å; F83-A92 HydrophobicContact CZ-CB 4.08Å; F83-F100 HydrophobicContact CZ-CZ 4.19Å; F83-L101 HydrophobicContact CD1-CD2 4.4Å; F83-L101 HydrophobicContact CE1-CD2 3.82Å; F83-M114 HydrophobicContact CB-CE 3.79Å; F83-M114 HydrophobicContact CB-SD 4.49Å; F83-I116 HydrophobicContact CB-CD1 3.25Å; F83-I116 HydrophobicContact CD1-CD1 3.72Å; F83-I116 HydrophobicContact CD2-CD1 3.36Å; F83-I116 HydrophobicContact CE1-CD1 4.34Å; F83-I116 HydrophobicContact CE2-CD1 4.03Å; F83-I116 HydrophobicContact CG-CD1 3.17Å; F83-I116 HydrophobicContact CZ-CD1 4.48Å
84I98.4Very high93.6Very high0 Ų043.7 Ų43.70%024%0.24CC..EExtended strand (participates in β ladder)trans-124142175.868.8-177.2000109.6V44 I66 R68 L69 I82 I90 R91 F93V44-I84 HydrophobicContact CG2-CD1 3.54Å; V44-I84 HydrophobicContact CG2-CG2 3.9Å; I66-I84 HydrophobicContact CD1-CD1 3.78Å; I66-I84 HydrophobicContact CD1-CG1 4.44Å; I66-I84 HydrophobicContact CG2-CB 4.23Å; I66-I84 HydrophobicContact CG2-CG2 4.46Å; R68-I84 WeakPolarHBondContact O-CA 3.38Å; L69-I84 HydrophobicContact CB-CG2 4.45Å; L69-I84 HydrophobicContact CD1-CG2 3.87Å; L69-I84 HydrophobicContact CG-CG2 3.99Å; I82-I84 HydrophobicContact CG2-CG2 4.34Å; I84-I90 WeakPolarHBondContact O-CA 3.44Å; I84-R91 HydrophobicContact CD1-CB 4.09Å; I84-R91 HydrophobicContact CG1-CB 3.83Å; I84-R91 PolarHBondContact N-O 3.26Å; I84-R91 PolarHBondContact O-N 3.03Å; I84-F93 HydrophobicContact CD1-CD2 4.45Å; I84-F93 HydrophobicContact CD1-CE2 3.57Å; I84-F93 HydrophobicContact CD1-CZ 4.3Å; I84-F93 HydrophobicContact CG1-CE2 4.08Å
85A97.7Very high94Very high0 Ų042.6 Ų42.60%023%0.227CC..EExtended strand (participates in β ladder)trans-104.8124.7168.500000109.1A67 R68 I111 M114A67-A85 PolarHBondContact N-O 3.01Å; R68-A85 HydrophobicContact CB-CB 4.29Å; R68-A85 PolarHBondContact O-N 3.21Å; A85-I111 HydrophobicContact CB-CB 4Å; A85-I111 HydrophobicContact CB-CD1 4.12Å; A85-I111 HydrophobicContact CB-CG2 3.68Å; A85-M114 HydrophobicContact CB-SD 4.3Å
86A95.8Very high94.5Very high1 Ų149.3 Ų49.31%0.00825%0.247CC..EExtended strand (participates in β ladder)trans-140.7123.6178.700000108.9P64 I66 S88 E89P64-A86 HydrophobicContact CB-CB 4.27Å; I66-A86 HydrophobicContact CD1-CB 3.83Å; A86-S88 PolarHBondContact O-N 3.42Å; A86-E89 PolarHBondContact N-O 2.85Å; A86-E89 PolarHBondContact O-N 3.44Å
87A94.1Very high95Very high45 Ų4543.8 Ų43.837%0.37222%0.222SC..THydrogen-bonded Turntrans51.1-125.2-167.100000111.4P64 S110 I111P64-A87 HydrophobicContact CB-CB 4.28Å; A87-S110 CarbonylContact O-C 3.57Å; A87-S110 WeakPolarHBondContact O-CA 3.43Å; A87-I111 PolarHBondContact O-N 2.87Å
88S94.3Very high95.5Very high29 Ų2948 Ų4820%0.20324%0.235CC..THydrogen-bonded Turntrans-966.817748.50000113.5A86 E104 T105A86-S88 PolarHBondContact O-N 3.42Å; S88-E104 WeakPolarHBondContact CB-OE1 3.26Å; S88-E104 PolarHBondContact OG-OE1 3Å; S88-T105 WeakPolarHBondContact O-CB 3.32Å; S88-T105 WeakPolarHBondContact O-CG2 3.45Å; S88-T105 PolarHBondContact O-N 3.14Å; S88-T105 VanDerWaalsContact O-N 3.12Å; S88-T105 PolarHBondContact O-OG1 3.36Å
89E95.8Very high96Very high39 Ų3947.9 Ų47.918%0.18223%0.226CC..EExtended strand (participates in β ladder)trans-110.6146.5-174-162.7-160.6163.800111.8A86 R91 S102 F103A86-E89 PolarHBondContact N-O 2.85Å; A86-E89 PolarHBondContact O-N 3.44Å; E89-R91 HydrophobicContact CG-CG 4.31Å; E89-R91 WeakPolarHBondContact OE1-CG 3.45Å; E89-S102 WeakPolarHBondContact OE1-CB 3.42Å; E89-S102 PolarHBondContact OE1-OG 3.48Å; E89-F103 WeakPolarHBondContact CA-O 3.29Å
90I97.6Very high96.3Very high0 Ų047.9 Ų47.90%023%0.225CC..EExtended strand (participates in β ladder)trans-112.4124.8168.1-65.9164.2000110.1F83 I84 S102 F103 T105 I111 M114 L121 L123F83-I90 HydrophobicContact CD1-CG2 4.12Å; I84-I90 WeakPolarHBondContact O-CA 3.44Å; I90-S102 CarbonylContact O-C 3.52Å; I90-S102 WeakPolarHBondContact O-CA 3.27Å; I90-F103 HydrophobicContact CB-CB 4.5Å; I90-F103 HydrophobicContact CD1-CD1 4.41Å; I90-F103 PolarHBondContact N-O 2.96Å; I90-F103 PolarHBondContact O-N 3.21Å; I90-T105 HydrophobicContact CD1-CG2 4.21Å; I90-I111 HydrophobicContact CD1-CD1 4.14Å; I90-I111 HydrophobicContact CG1-CD1 3.82Å; I90-M114 HydrophobicContact CD1-SD 4.1Å; I90-M114 HydrophobicContact CG1-SD 4.22Å; I90-M114 HydrophobicContact CG2-SD 4.34Å; I90-L121 HydrophobicContact CD1-CD1 4.08Å; I90-L121 HydrophobicContact CD1-CD2 3.37Å; I90-L121 HydrophobicContact CD1-CG 4.09Å; I90-L123 HydrophobicContact CD1-CD1 3.36Å; I90-L123 HydrophobicContact CD1-CD2 3.43Å; I90-L123 VanDerWaalsContact CD1-CD2 3.43Å; I90-L123 HydrophobicContact CD1-CG 3.98Å
91R97.6Very high96.4Very high29 Ų2947 Ų4711%0.10922%0.223CC..EExtended strand (participates in β ladder)trans-114.1138.9175.9-64177.5-71.4162.7-0.2109.1F83 I84 E89 F93 L101F83-R91 WeakPolarHBondContact CA-O 3.12Å; I84-R91 HydrophobicContact CD1-CB 4.09Å; I84-R91 HydrophobicContact CG1-CB 3.83Å; I84-R91 PolarHBondContact N-O 3.26Å; I84-R91 PolarHBondContact O-N 3.03Å; E89-R91 HydrophobicContact CG-CG 4.31Å; E89-R91 WeakPolarHBondContact OE1-CG 3.45Å; R91-F93 HydrophobicContact CB-CE2 3.73Å; R91-F93 HydrophobicContact CB-CZ 4.15Å; R91-L101 WeakPolarHBondContact CA-O 3.3Å
92A97.5Very high96.4Very high0 Ų046.6 Ų46.60%023%0.23CC..EExtended strand (participates in β ladder)trans-124.9137.517700000112.8I82 F83 Q99 F100 L101I82-A92 CarbonylContact O-C 3.4Å; I82-A92 VanDerWaalsContact O-CA 3.23Å; I82-A92 WeakPolarHBondContact O-CA 3.36Å; F83-A92 HydrophobicContact CD1-CB 3.44Å; F83-A92 VanDerWaalsContact CD1-CB 3.44Å; F83-A92 HydrophobicContact CD2-CB 4.46Å; F83-A92 HydrophobicContact CE1-CB 3.51Å; F83-A92 HydrophobicContact CG-CB 3.95Å; F83-A92 HydrophobicContact CZ-CB 4.08Å; A92-Q99 CarbonylContact O-C 3.59Å; A92-Q99 WeakPolarHBondContact O-CA 3.35Å; A92-F100 HydrophobicContact CB-CD1 4.26Å; A92-F100 HydrophobicContact CB-CE1 3.57Å; A92-F100 HydrophobicContact CB-CE2 4.02Å; A92-F100 HydrophobicContact CB-CZ 3.43Å; A92-F100 VanDerWaalsContact CB-CZ 3.43Å; A92-F100 WeakPolarHBondContact O-CD1 3.37Å; A92-F100 PolarHBondContact O-N 2.91Å; A92-L101 HydrophobicContact CB-CB 3.61Å; A92-L101 HydrophobicContact CB-CD2 4.23Å; A92-L101 PolarHBondContact N-O 2.88Å; A92-L101 PolarHBondContact O-N 3.07Å
93F97.9Very high96.3Very high7 Ų747.8 Ų47.83%0.03124%0.235CC..EExtended strand (participates in β ladder)trans-124144.1-175.4-58-94.7000110.4T60 I82 I84 R91 K98 Q99T60-F93 HydrophobicContact CG2-CD1 4.42Å; T60-F93 HydrophobicContact CG2-CE1 3.87Å; T60-F93 HydrophobicContact CG2-CZ 4.18Å; I82-F93 HydrophobicContact CB-CB 4.37Å; I82-F93 PolarHBondContact N-O 3.31Å; I82-F93 PolarHBondContact O-N 3.44Å; I84-F93 HydrophobicContact CD1-CD2 4.45Å; I84-F93 HydrophobicContact CD1-CE2 3.57Å; I84-F93 HydrophobicContact CD1-CZ 4.3Å; I84-F93 HydrophobicContact CG1-CE2 4.08Å; R91-F93 HydrophobicContact CB-CE2 3.73Å; R91-F93 HydrophobicContact CB-CZ 4.15Å; F93-K98 WeakPolarHBondContact CA-O 3.05Å; F93-Q99 HydrophobicContact CD1-CB 3.86Å; F93-Q99 HydrophobicContact CD1-CG 4.37Å; F93-Q99 HydrophobicContact CE1-CB 3.67Å; F93-Q99 HydrophobicContact CE1-CG 3.98Å; F93-Q99 HydrophobicContact CZ-CB 4.4Å; F93-Q99 HydrophobicContact CZ-CG 4.21Å
94T96.4Very high96.1Very high29 Ų2951.9 Ų51.918%0.17826%0.255CS..  trans-70.6162.3165.163.80000110.3R96 G97 K98 F100T94-R96 PolarHBondContact O-N 3.31Å; T94-G97 PolarHBondContact O-N 3.17Å; T94-K98 HydrophobicContact CG2-CB 4.45Å; T94-K98 PolarHBondContact N-O 3.48Å; T94-K98 PolarHBondContact OG1-N 2.97Å; T94-K98 PolarHBondContact OG1-O 3.42Å; T94-F100 HydrophobicContact CG2-CD1 3.92Å
95K93.8Very high95.8Very high86 Ų8652.4 Ų52.437%0.37426%0.258SS..THydrogen-bonded Turntrans-55-8.4171.370.9-176.4178.5-163.80116.2L24 E80L24-K95 HydrophobicContact CD1-CB 4.06Å; E80-K95 HydrophobicContact CB-CD 4.45Å; E80-K95 IonicContact OE1-NZ 3.69Å; E80-K95 PolarHBondContact OE1-NZ 3.12Å; E80-K95 WeakPolarHBondContact OE2-CD 3.29Å; E80-K95 WeakPolarHBondContact OE2-CE 3.29Å; E80-K95 IonicContact OE2-NZ 3.44Å; E80-K95 PolarHBondContact OE2-NZ 3.24Å
96R93.4Very high95.3Very high209 Ų20957 Ų5779%0.78928%0.283SS*.THydrogen-bonded Turntrans-104.62.2175.6-62-172.7-177.1-176.91.5113.4T94T94-R96 PolarHBondContact O-N 3.31Å
97G94.1Very high94.9Very high20 Ų2057.6 Ų57.621%0.20629%0.285CS..SBendtrans86.42.3179.100000115.6F58 T94 Q99F58-G97 VanDerWaalsContact CD1-CA 3.46Å; F58-G97 VanDerWaalsContact CG-CA 3.43Å; T94-G97 PolarHBondContact O-N 3.17Å; G97-Q99 PolarHBondContact O-N 3.29Å
98K96.8Very high94.5Very high155 Ų15561.6 Ų61.667%0.67431%0.305SS*.  trans-72.5117.9171.4-175.3179.8179.9-178.50109.5F93 T94F93-K98 WeakPolarHBondContact CA-O 3.05Å; T94-K98 HydrophobicContact CG2-CB 4.45Å; T94-K98 PolarHBondContact N-O 3.48Å; T94-K98 PolarHBondContact OG1-N 2.97Å; T94-K98 PolarHBondContact OG1-O 3.42Å
99Q97.3Very high94.3Very high89 Ų8963.7 Ų63.742%0.41631%0.312SS..EExtended strand (participates in β ladder)trans-67.2133.2170.5-168.7175.1-41.300109.9A92 F93 G97A92-Q99 CarbonylContact O-C 3.59Å; A92-Q99 WeakPolarHBondContact O-CA 3.35Å; F93-Q99 HydrophobicContact CD1-CB 3.86Å; F93-Q99 HydrophobicContact CD1-CG 4.37Å; F93-Q99 HydrophobicContact CE1-CB 3.67Å; F93-Q99 HydrophobicContact CE1-CG 3.98Å; F93-Q99 HydrophobicContact CZ-CB 4.4Å; F93-Q99 HydrophobicContact CZ-CG 4.21Å; G97-Q99 PolarHBondContact O-N 3.29Å
100F96.3Very high94.2Very high96 Ų9664 Ų6442%0.42132%0.319SS..EExtended strand (participates in β ladder)trans-130.3-12.1179.172.4-88.3000113.6K81 F83 A92 T94K81-F100 HydrophobicContact CB-CE1 4.22Å; K81-F100 HydrophobicContact CB-CZ 4Å; K81-F100 HydrophobicContact CD-CE1 3.75Å; K81-F100 HydrophobicContact CD-CZ 3.85Å; K81-F100 HydrophobicContact CG-CE1 4.32Å; K81-F100 HydrophobicContact CG-CZ 4.02Å; F83-F100 HydrophobicContact CZ-CZ 4.19Å; A92-F100 HydrophobicContact CB-CD1 4.26Å; A92-F100 HydrophobicContact CB-CE1 3.57Å; A92-F100 HydrophobicContact CB-CE2 4.02Å; A92-F100 HydrophobicContact CB-CZ 3.43Å; A92-F100 VanDerWaalsContact CB-CZ 3.43Å; A92-F100 WeakPolarHBondContact O-CD1 3.37Å; A92-F100 PolarHBondContact O-N 2.91Å; T94-F100 HydrophobicContact CG2-CD1 3.92Å
101L96.3Very high94.1Very high48 Ų4864 Ų6425%0.25132%0.319SS..EExtended strand (participates in β ladder)trans-135.6140.2173.4-173.367.9000109.5F83 R91 A92 F103F83-L101 HydrophobicContact CD1-CD2 4.4Å; F83-L101 HydrophobicContact CE1-CD2 3.82Å; R91-L101 WeakPolarHBondContact CA-O 3.3Å; A92-L101 HydrophobicContact CB-CB 3.61Å; A92-L101 HydrophobicContact CB-CD2 4.23Å; A92-L101 PolarHBondContact N-O 2.88Å; A92-L101 PolarHBondContact O-N 3.07Å; L101-F103 HydrophobicContact CG-CB 4.4Å
102S96.4Very high94.1Very high73 Ų7367 Ų6751%0.5133%0.332SS..EExtended strand (participates in β ladder)trans-140.3116.4164.3161.50000104.9E89 I90E89-S102 WeakPolarHBondContact OE1-CB 3.42Å; E89-S102 PolarHBondContact OE1-OG 3.48Å; I90-S102 CarbonylContact O-C 3.52Å; I90-S102 WeakPolarHBondContact O-CA 3.27Å
103F96.5Very high94Very high25 Ų2567 Ų6711%0.1133%0.332CS..EExtended strand (participates in β ladder)trans-128.1107.1-174.5174.4-130.1000108.7E89 I90 L101 T105 L121 Y132 C135E89-F103 WeakPolarHBondContact CA-O 3.29Å; I90-F103 HydrophobicContact CB-CB 4.5Å; I90-F103 HydrophobicContact CD1-CD1 4.41Å; I90-F103 PolarHBondContact N-O 2.96Å; I90-F103 PolarHBondContact O-N 3.21Å; L101-F103 HydrophobicContact CG-CB 4.4Å; F103-T105 HydrophobicContact CD1-CG2 4.04Å; F103-T105 HydrophobicContact CE1-CG2 3.79Å; F103-T105 HydrophobicContact CZ-CG2 4.42Å; F103-L121 HydrophobicContact CD1-CD2 4.07Å; F103-L121 HydrophobicContact CE1-CD2 4.19Å; F103-Y132 AromaticContact CE1-CD1 3.84Å; F103-Y132 HydrophobicContact CE1-CD1 3.84Å; F103-Y132 HydrophobicContact CE1-CD2 4.15Å; F103-Y132 HydrophobicContact CE1-CE1 4.01Å; F103-Y132 HydrophobicContact CE1-CE2 4.3Å; F103-Y132 AromaticContact CE1-CG 3.91Å; F103-Y132 HydrophobicContact CE1-CG 3.91Å; F103-Y132 AromaticContact CZ-CD1 3.53Å; F103-Y132 HydrophobicContact CZ-CD1 3.53Å; F103-Y132 AromaticContact CZ-CE1 3.53Å; F103-Y132 HydrophobicContact CZ-CE1 3.53Å; F103-Y132 HydrophobicContact CZ-CG 4.09Å; F103-C135 HydrophobicContact CD1-CB 4.45Å; F103-C135 HydrophobicContact CD2-CB 3.72Å; F103-C135 HydrophobicContact CE1-CB 4.47Å; F103-C135 HydrophobicContact CE2-CB 3.76Å; F103-C135 HydrophobicContact CG-CB 4.1Å; F103-C135 HydrophobicContact CZ-CB 4.15Å
104E94.7Very high94Very high110 Ų11066.7 Ų66.751%0.51433%0.331SS..EExtended strand (participates in β ladder)trans-79.6119.5170.9-165.663.8-13600108.6S88S88-E104 WeakPolarHBondContact CB-OE1 3.26Å; S88-E104 PolarHBondContact OG-OE1 3Å
105T91.9Very high94.1Very high11 Ų1166.8 Ų66.87%0.06733%0.329CS..  trans-80.9167.4-179.670.10000110.8S88 I90 F103 L107 I111 L123S88-T105 WeakPolarHBondContact O-CB 3.32Å; S88-T105 WeakPolarHBondContact O-CG2 3.45Å; S88-T105 PolarHBondContact O-N 3.14Å; S88-T105 VanDerWaalsContact O-N 3.12Å; S88-T105 PolarHBondContact O-OG1 3.36Å; I90-T105 HydrophobicContact CD1-CG2 4.21Å; F103-T105 HydrophobicContact CD1-CG2 4.04Å; F103-T105 HydrophobicContact CE1-CG2 3.79Å; F103-T105 HydrophobicContact CZ-CG2 4.42Å; T105-L107 PolarHBondContact O-N 2.7Å; T105-L107 WeakPolarHBondContact OG1-CB 3.29Å; T105-L107 PolarHBondContact OG1-N 2.89Å; T105-I111 HydrophobicContact CG2-CD1 4.18Å; T105-L123 HydrophobicContact CG2-CD1 3.62Å
106N86.8Confident94.2Very high97 Ų9763.2 Ų63.252%0.51931%0.314SS..SBendtrans-81.67172.465.86.6000113.5Y132 D137N106-Y132 VanDerWaalsContact CG-OH 3.32Å; N106-Y132 PolarHBondContact N-OH 3.33Å; N106-Y132 PolarHBondContact OD1-OH 3.21Å; N106-D137 PolarHBondContact ND2-OD2 2.82Å
107L87.8Confident94.2Very high12 Ų1254 Ų546%0.06328%0.281CS..  trans-72.4132.2-177.3-66.4171.9000110.8T105 E109 I111 A125 I128 N130T105-L107 PolarHBondContact O-N 2.7Å; T105-L107 WeakPolarHBondContact OG1-CB 3.29Å; T105-L107 PolarHBondContact OG1-N 2.89Å; L107-E109 VanDerWaalsContact C-N 3.29Å; L107-I111 HydrophobicContact CD1-CG1 3.73Å; L107-A125 HydrophobicContact CD1-CB 4.47Å; L107-A125 HydrophobicContact CD2-CB 4.28Å; L107-I128 HydrophobicContact CD2-CB 4.12Å; L107-I128 HydrophobicContact CD2-CG2 3.56Å; L107-N130 WeakPolarHBondContact CD2-OD1 3.36Å
108T85.6Confident94.1Very high129 Ų12954 Ų5479%0.79128%0.281SS*.SBendtrans-80-14.3173.652.90000113.1
109E90.5Very high93.9Very high74 Ų7449.4 Ų49.435%0.34627%0.269SS..SBendtrans-117.9159-176.1-67.1177.5-176.500110.7L107 I111 A125 S126L107-E109 VanDerWaalsContact C-N 3.29Å; E109-I111 PolarHBondContact O-N 3.29Å; E109-A125 HydrophobicContact CB-CB 3.99Å; E109-S126 VanDerWaalsContact OE2-CB 3.27Å; E109-S126 WeakPolarHBondContact OE2-CB 3.34Å; E109-S126 PolarHBondContact OE2-N 3.38Å
110S92.8Very high93.8Very high46 Ų4646.1 Ų46.132%0.32225%0.254SS..  trans-62.3136.5174.367.60000111.7A87 K112A87-S110 CarbonylContact O-C 3.57Å; A87-S110 WeakPolarHBondContact O-CA 3.43Å; S110-K112 VanDerWaalsContact OG-CE 3.32Å; S110-K112 WeakPolarHBondContact OG-CE 3.48Å; S110-K112 PolarHBondContact OG-NZ 2.85Å
111I96.8Very high93.9Very high0 Ų042.2 Ų42.20%024%0.238CC..  trans-60.6135.8170.4-59.1163.6000109.6A67 A85 A87 I90 T105 L107 E109 A113 L123 S124A67-I111 VanDerWaalsContact CB-O 3.26Å; A67-I111 WeakPolarHBondContact CB-O 3.12Å; A85-I111 HydrophobicContact CB-CB 4Å; A85-I111 HydrophobicContact CB-CD1 4.12Å; A85-I111 HydrophobicContact CB-CG2 3.68Å; A87-I111 PolarHBondContact O-N 2.87Å; I90-I111 HydrophobicContact CD1-CD1 4.14Å; I90-I111 HydrophobicContact CG1-CD1 3.82Å; T105-I111 HydrophobicContact CG2-CD1 4.18Å; L107-I111 HydrophobicContact CD1-CG1 3.73Å; E109-I111 PolarHBondContact O-N 3.29Å; I111-A113 WeakPolarHBondContact CG2-O 3.37Å; I111-L123 HydrophobicContact CD1-CD1 4.3Å; I111-S124 WeakPolarHBondContact CA-O 3.43Å
112K95.8Very high94Very high90 Ų9040 Ų4039%0.39123%0.226SC..  trans-113-37.5178.8-60.6-55.9-172.4-166.20112.4R68 S110 S124R68-K112 PolarHBondContact NE-O 3.45Å; R68-K112 PolarHBondContact NH2-O 2.84Å; S110-K112 VanDerWaalsContact OG-CE 3.32Å; S110-K112 WeakPolarHBondContact OG-CE 3.48Å; S110-K112 PolarHBondContact OG-NZ 2.85Å; K112-S124 PolarHBondContact N-O 3.08Å
113A97.3Very high94Very high0 Ų036.5 Ų36.50%020%0.202CC..EExtended strand (participates in β ladder)trans-136.6155.4174.200000111.9I111 S124 V150I111-A113 WeakPolarHBondContact CG2-O 3.37Å; A113-S124 VanDerWaalsContact CB-OG 3.26Å; A113-S124 WeakPolarHBondContact CB-OG 3.42Å; A113-S124 PolarHBondContact N-O 3.36Å; A113-S124 PolarHBondContact N-OG 2.75Å; A113-S124 PolarHBondContact O-N 2.7Å; A113-V150 HydrophobicContact CB-CG1 3.93Å
114M97.6Very high94Very high1 Ų135.3 Ų35.31%0.00520%0.197CC..EExtended strand (participates in β ladder)trans-150.4136.7-176.5175.3173.875.100108.9R68 E70 F83 A85 I90 I116 L121 F122 L123R68-M114 HydrophobicContact CB-CB 4.4Å; R68-M114 HydrophobicContact CG-CB 4.18Å; E70-M114 HydrophobicContact CB-CE 4.05Å; E70-M114 HydrophobicContact CG-CE 4.46Å; F83-M114 HydrophobicContact CB-CE 3.79Å; F83-M114 HydrophobicContact CB-SD 4.49Å; A85-M114 HydrophobicContact CB-SD 4.3Å; I90-M114 HydrophobicContact CD1-SD 4.1Å; I90-M114 HydrophobicContact CG1-SD 4.22Å; I90-M114 HydrophobicContact CG2-SD 4.34Å; M114-I116 HydrophobicContact CE-CD1 4.13Å; M114-I116 HydrophobicContact CG-CG1 4.21Å; M114-I116 HydrophobicContact SD-CD1 4.24Å; M114-I116 HydrophobicContact SD-CG1 4.5Å; M114-L121 HydrophobicContact CG-CD1 3.89Å; M114-L121 HydrophobicContact SD-CD1 3.91Å; M114-F122 CarbonylContact C-O 3.6Å; M114-F122 VanDerWaalsContact CA-O 3.28Å; M114-F122 WeakPolarHBondContact CA-O 3.41Å; M114-L123 HydrophobicContact CB-CD2 3.87Å; M114-L123 HydrophobicContact CG-CD2 3.56Å; M114-L123 HydrophobicContact SD-CD2 4.05Å
115H97.6Very high94Very high32 Ų3230.1 Ų30.115%0.14817%0.172CC..EExtended strand (participates in β ladder)trans-133.6144.8168.6-177.275.7000109.9F122 V150 C152H115-F122 HydrophobicContact CB-CB 4.32Å; H115-F122 HydrophobicContact CB-CD2 4.48Å; H115-F122 AromaticContact CD2-CD2 3.87Å; H115-F122 PolarHBondContact N-O 3.31Å; H115-F122 PolarHBondContact O-N 3.16Å; H115-V150 HydrophobicContact CB-CG1 4.5Å; H115-V150 WeakPolarHBondContact CB-O 3.43Å; H115-C152 PolarHBondContact CD2-N 2.79Å; H115-C152 VanDerWaalsContact CD2-N 3.26Å
116I95.6Very high94Very high11 Ų1131.1 Ų31.16%0.05618%0.18CC..EExtended strand (participates in β ladder)trans-127.4128.1-174.5-55.2-178.7000108.7E70 F83 M114 L121E70-I116 HydrophobicContact CB-CD1 4.32Å; F83-I116 HydrophobicContact CB-CD1 3.25Å; F83-I116 HydrophobicContact CD1-CD1 3.72Å; F83-I116 HydrophobicContact CD2-CD1 3.36Å; F83-I116 HydrophobicContact CE1-CD1 4.34Å; F83-I116 HydrophobicContact CE2-CD1 4.03Å; F83-I116 HydrophobicContact CG-CD1 3.17Å; F83-I116 HydrophobicContact CZ-CD1 4.48Å; M114-I116 HydrophobicContact CE-CD1 4.13Å; M114-I116 HydrophobicContact CG-CG1 4.21Å; M114-I116 HydrophobicContact SD-CD1 4.24Å; M114-I116 HydrophobicContact SD-CG1 4.5Å; I116-L121 HydrophobicContact CD1-CD1 4.2Å; I116-L121 HydrophobicContact CG1-CD1 3.77Å
117S94.1Very high94.4Very high14 Ų1427.4 Ų27.410%0.09816%0.159CC..EExtended strand (participates in β ladder)trans-134.7100174.6-164.90000109.1S119 D120S117-S119 PolarHBondContact O-N 3.46Å; S117-D120 PolarHBondContact N-O 3.49Å; S117-D120 WeakPolarHBondContact O-CB 3.49Å; S117-D120 PolarHBondContact O-N 3.49Å
118G91.6Very high94.8Very high20 Ų2027.9 Ų27.921%0.20616%0.161CC..THydrogen-bonded Turntrans62.8-119.8-17500000112.3G73G73-G118 WeakPolarHBondContact O-CA 3.31Å
119S92.9Very high95.3Very high59 Ų5921.8 Ų21.841%0.41312%0.124SC..THydrogen-bonded Turntrans-87.6-9.3174.348.30000113.6S117 D134S117-S119 PolarHBondContact O-N 3.46Å; S119-D134 VanDerWaalsContact CB-OD1 3.29Å; S119-D134 WeakPolarHBondContact CB-OD1 3.49Å; S119-D134 PolarHBondContact O-N 2.79Å
120D96.1Very high95.6Very high21 Ų2118.2 Ų18.211%0.11211%0.107CC..EExtended strand (participates in β ladder)trans-85.8133.1-180-64.2-66.2000111.2S117 F122 H131 Y132 C133S117-D120 PolarHBondContact N-O 3.49Å; S117-D120 WeakPolarHBondContact O-CB 3.49Å; S117-D120 PolarHBondContact O-N 3.49Å; D120-F122 HydrophobicContact CB-CE2 3.79Å; D120-F122 HydrophobicContact CB-CZ 3.76Å; D120-H131 IonicContact OD1-CD2 2.91Å; D120-H131 IonicContact OD1-CE1 2.84Å; D120-H131 PolarHBondContact OD1-CE1 3.13Å; D120-H131 IonicContact OD1-NE2 3.38Å; D120-H131 PolarHBondContact OD1-NE2 2.91Å; D120-Y132 WeakPolarHBondContact CA-O 3.21Å; D120-C133 PolarHBondContact OD1-SG 2.89Å
121L96.9Very high95.9Very high14 Ų1416.2 Ų16.27%0.0739%0.092CC..EExtended strand (participates in β ladder)trans-127.9115.7-175.4177.968.6000109I90 F103 M114 I116 L123 H131 Y132I90-L121 HydrophobicContact CD1-CD1 4.08Å; I90-L121 HydrophobicContact CD1-CD2 3.37Å; I90-L121 HydrophobicContact CD1-CG 4.09Å; F103-L121 HydrophobicContact CD1-CD2 4.07Å; F103-L121 HydrophobicContact CE1-CD2 4.19Å; M114-L121 HydrophobicContact CG-CD1 3.89Å; M114-L121 HydrophobicContact SD-CD1 3.91Å; I116-L121 HydrophobicContact CD1-CD1 4.2Å; I116-L121 HydrophobicContact CG1-CD1 3.77Å; L121-L123 HydrophobicContact CD1-CD2 3.76Å; L121-L123 HydrophobicContact CD2-CD1 4.19Å; L121-L123 HydrophobicContact CD2-CD2 4.26Å; L121-L123 HydrophobicContact CD2-CG 4.34Å; L121-L123 HydrophobicContact CG-CD1 4.39Å; L121-L123 HydrophobicContact CG-CD2 3.77Å; L121-L123 HydrophobicContact CG-CG 3.99Å; L121-H131 WeakPolarHBondContact O-CA 3.47Å; L121-Y132 PolarHBondContact N-O 3.48Å; L121-Y132 PolarHBondContact O-N 2.92Å
122F97.9Very high95.9Very high0 Ų016.4 Ų16.40%09%0.093CC..EExtended strand (participates in β ladder)trans-109.1117.6-177.4-55.2-75.7000109M114 H115 D120 Y129 H131 V150 C152 I161 P163M114-F122 CarbonylContact C-O 3.6Å; M114-F122 VanDerWaalsContact CA-O 3.28Å; M114-F122 WeakPolarHBondContact CA-O 3.41Å; H115-F122 HydrophobicContact CB-CB 4.32Å; H115-F122 HydrophobicContact CB-CD2 4.48Å; H115-F122 AromaticContact CD2-CD2 3.87Å; H115-F122 PolarHBondContact N-O 3.31Å; H115-F122 PolarHBondContact O-N 3.16Å; D120-F122 HydrophobicContact CB-CE2 3.79Å; D120-F122 HydrophobicContact CB-CZ 3.76Å; F122-Y129 HydrophobicContact CB-CE2 4.16Å; F122-Y129 HydrophobicContact CD1-CE2 4.21Å; F122-Y129 WeakPolarHBondContact CD1-OH 3.46Å; F122-H131 HydrophobicContact CD1-CB 3.95Å; F122-H131 AromaticContact CD1-CD2 3.63Å; F122-H131 AromaticContact CD1-CG 3.83Å; F122-H131 HydrophobicContact CE1-CB 4.13Å; F122-H131 AromaticContact CE1-CD2 3.28Å; F122-H131 WeakPolarHBondContact CE1-CD2 3.19Å; F122-H131 AromaticContact CE1-CG 3.55Å; F122-H131 AromaticContact CE1-NE2 3.69Å; F122-H131 AromaticContact CZ-CD2 3.9Å; F122-H131 AromaticContact CZ-NE2 3.96Å; F122-V150 HydrophobicContact CB-CG2 4.02Å; F122-C152 HydrophobicContact CD2-CB 3.83Å; F122-C152 HydrophobicContact CE2-CB 3.5Å; F122-C152 VanDerWaalsContact CE2-CB 3.5Å; F122-C152 HydrophobicContact CZ-CB 3.92Å; F122-I161 HydrophobicContact CE1-CG2 3.68Å; F122-I161 HydrophobicContact CZ-CG2 3.61Å; F122-P163 HydrophobicContact CD1-CB 4.45Å; F122-P163 HydrophobicContact CE1-CG 4.33Å
123L97.4Very high95.9Very high1 Ų113.8 Ų13.81%0.0059%0.086CC..EExtended strand (participates in β ladder)trans-122.2144.9-173.5-53.6-178.8000110.8I90 T105 I111 M114 L121 Y129 N130 Y132I90-L123 HydrophobicContact CD1-CD1 3.36Å; I90-L123 HydrophobicContact CD1-CD2 3.43Å; I90-L123 VanDerWaalsContact CD1-CD2 3.43Å; I90-L123 HydrophobicContact CD1-CG 3.98Å; T105-L123 HydrophobicContact CG2-CD1 3.62Å; I111-L123 HydrophobicContact CD1-CD1 4.3Å; M114-L123 HydrophobicContact CB-CD2 3.87Å; M114-L123 HydrophobicContact CG-CD2 3.56Å; M114-L123 HydrophobicContact SD-CD2 4.05Å; L121-L123 HydrophobicContact CD1-CD2 3.76Å; L121-L123 HydrophobicContact CD2-CD1 4.19Å; L121-L123 HydrophobicContact CD2-CD2 4.26Å; L121-L123 HydrophobicContact CD2-CG 4.34Å; L121-L123 HydrophobicContact CG-CD1 4.39Å; L121-L123 HydrophobicContact CG-CD2 3.77Å; L121-L123 HydrophobicContact CG-CG 3.99Å; L123-Y129 WeakPolarHBondContact O-CA 3.45Å; L123-Y129 WeakPolarHBondContact O-CD2 3.47Å; L123-N130 PolarHBondContact N-O 3.36Å; L123-N130 PolarHBondContact O-N 2.94Å; L123-Y132 HydrophobicContact CD1-CD2 3.93Å; L123-Y132 HydrophobicContact CD1-CE2 3.7Å; L123-Y132 HydrophobicContact CG-CD2 4.37Å; L123-Y132 HydrophobicContact CG-CE2 4.43Å
124S96.3Very high95.7Very high0 Ų019.1 Ų19.10%011%0.114CC..EExtended strand (participates in β ladder)trans-125.3140.5165.174.10000112I111 K112 A113 I128I111-S124 WeakPolarHBondContact CA-O 3.43Å; K112-S124 PolarHBondContact N-O 3.08Å; A113-S124 VanDerWaalsContact CB-OG 3.26Å; A113-S124 WeakPolarHBondContact CB-OG 3.42Å; A113-S124 PolarHBondContact N-O 3.36Å; A113-S124 PolarHBondContact N-OG 2.75Å; A113-S124 PolarHBondContact O-N 2.7Å; S124-I128 CarbonylContact C-O 3.53Å; S124-I128 VanDerWaalsContact CA-O 3.29Å; S124-I128 WeakPolarHBondContact CA-O 3.32Å
125A94.6Very high95.5Very high0 Ų021.4 Ų21.40%013%0.13CC..  trans-95.3-144.4161.600000109.2L107 E109 I128L107-A125 HydrophobicContact CD1-CB 4.47Å; L107-A125 HydrophobicContact CD2-CB 4.28Å; E109-A125 HydrophobicContact CB-CB 3.99Å; A125-I128 HydrophobicContact CB-CB 4.29Å; A125-I128 PolarHBondContact N-O 3.24Å
126S92.8Very high95.4Very high33 Ų3326.8 Ų26.823%0.23115%0.153CC..SBendtrans-73.3-47175.1-67.80000112.8E109 K146 I147E109-S126 VanDerWaalsContact OE2-CB 3.27Å; E109-S126 WeakPolarHBondContact OE2-CB 3.34Å; E109-S126 PolarHBondContact OE2-N 3.38Å; S126-K146 CarbonylContact O-C 3.54Å; S126-K146 WeakPolarHBondContact O-CA 3.31Å; S126-I147 PolarHBondContact O-N 3Å
127Y94.5Very high95.4Very high19 Ų1929.6 Ų29.68%0.07517%0.168CC..SBendtrans-123-14.3179.5-62.2-91.5000113.3S143 D145 K146 P532Y127-S143 WeakPolarHBondContact O-CB 3.27Å; Y127-S143 PolarHBondContact O-N 3.06Å; Y127-D145 VanDerWaalsContact CD1-C 3.47Å; Y127-K146 HydrophobicContact CD1-CG 4.39Å; Y127-K146 HydrophobicContact CE1-CG 3.71Å; Y127-K146 HydrophobicContact CE2-CG 4.04Å; Y127-K146 WeakPolarHBondContact OH-CE 3.42Å; Y127-P532 HydrophobicContact CE1-CB 4.26Å
128I95.5Very high95.5Very high22 Ų2233.5 Ų33.511%0.11319%0.185CC..EExtended strand (participates in β ladder)trans-94.6134.2-174-63.1168.5000109.1L107 S124 A125 N130 Y140 L142L107-I128 HydrophobicContact CD2-CB 4.12Å; L107-I128 HydrophobicContact CD2-CG2 3.56Å; S124-I128 CarbonylContact C-O 3.53Å; S124-I128 VanDerWaalsContact CA-O 3.29Å; S124-I128 WeakPolarHBondContact CA-O 3.32Å; A125-I128 HydrophobicContact CB-CB 4.29Å; A125-I128 PolarHBondContact N-O 3.24Å; I128-N130 WeakPolarHBondContact CG2-OD1 3.15Å; I128-Y140 HydrophobicContact CB-CE2 4.44Å; I128-Y140 HydrophobicContact CG1-CE2 4.31Å; I128-Y140 HydrophobicContact CG2-CD2 3.95Å; I128-Y140 HydrophobicContact CG2-CE2 3.42Å; I128-Y140 VanDerWaalsContact CG2-CE2 3.42Å; I128-L142 HydrophobicContact CG1-CD1 3.87Å
129Y97.1Very high95.8Very high0 Ų035.3 Ų35.30%019%0.188CC..EExtended strand (participates in β ladder)trans-112.7136.7164.7161.4-96.3000109.7F122 L123 H131 Y140 Y141 V150 P163 L165 L175F122-Y129 HydrophobicContact CB-CE2 4.16Å; F122-Y129 HydrophobicContact CD1-CE2 4.21Å; F122-Y129 WeakPolarHBondContact CD1-OH 3.46Å; L123-Y129 WeakPolarHBondContact O-CA 3.45Å; L123-Y129 WeakPolarHBondContact O-CD2 3.47Å; Y129-H131 HydrophobicContact CE1-CB 4.36Å; Y129-Y140 WeakPolarHBondContact O-CA 3.44Å; Y129-Y141 PolarHBondContact N-O 3.15Å; Y129-Y141 PolarHBondContact O-N 3.32Å; Y129-V150 HydrophobicContact CD2-CG2 4.11Å; Y129-V150 HydrophobicContact CE2-CG2 3.86Å; Y129-P163 HydrophobicContact CE2-CB 4.28Å; Y129-P163 VanDerWaalsContact OH-CB 3.22Å; Y129-P163 WeakPolarHBondContact OH-CB 2.99Å; Y129-P163 WeakPolarHBondContact OH-CG 3.33Å; Y129-L165 HydrophobicContact CD2-CD2 3.55Å; Y129-L165 HydrophobicContact CE2-CD2 4.02Å; Y129-L165 HydrophobicContact CG-CD1 4.2Å; Y129-L165 HydrophobicContact CG-CD2 4.02Å; Y129-L175 HydrophobicContact CD1-CD1 3.87Å; Y129-L175 HydrophobicContact CE1-CD1 3.81Å; Y129-L175 HydrophobicContact CG-CD1 4.45Å
130N97.1Very high95.9Very high0 Ų037.8 Ų37.80%019%0.189CC..EExtended strand (participates in β ladder)trans-130.5143.1171.2-77.193.2000110.8L107 L123 I128 Y132 H139L107-N130 WeakPolarHBondContact CD2-OD1 3.36Å; L123-N130 PolarHBondContact N-O 3.36Å; L123-N130 PolarHBondContact O-N 2.94Å; I128-N130 WeakPolarHBondContact CG2-OD1 3.15Å; N130-Y132 HydrophobicContact CB-CD2 4.11Å; N130-Y132 HydrophobicContact CB-CE2 3.4Å; N130-H139 WeakPolarHBondContact CA-O 3.43Å
131H97.6Very high95.9Very high3 Ų338.7 Ų38.71%0.01419%0.191CC..EExtended strand (participates in β ladder)trans-115.2124167.5169.6-142.4000109.3D120 L121 F122 Y129 Q138 H139D120-H131 IonicContact OD1-CD2 2.91Å; D120-H131 IonicContact OD1-CE1 2.84Å; D120-H131 PolarHBondContact OD1-CE1 3.13Å; D120-H131 IonicContact OD1-NE2 3.38Å; D120-H131 PolarHBondContact OD1-NE2 2.91Å; L121-H131 WeakPolarHBondContact O-CA 3.47Å; F122-H131 HydrophobicContact CD1-CB 3.95Å; F122-H131 AromaticContact CD1-CD2 3.63Å; F122-H131 AromaticContact CD1-CG 3.83Å; F122-H131 HydrophobicContact CE1-CB 4.13Å; F122-H131 AromaticContact CE1-CD2 3.28Å; F122-H131 WeakPolarHBondContact CE1-CD2 3.19Å; F122-H131 AromaticContact CE1-CG 3.55Å; F122-H131 AromaticContact CE1-NE2 3.69Å; F122-H131 AromaticContact CZ-CD2 3.9Å; F122-H131 AromaticContact CZ-NE2 3.96Å; Y129-H131 HydrophobicContact CE1-CB 4.36Å; H131-Q138 PolarHBondContact O-N 3.2Å; H131-H139 HydrophobicContact CB-CB 4.04Å; H131-H139 AromaticContact CE1-CD2 3.97Å; H131-H139 PolarHBondContact N-O 3.13Å; H131-H139 AromaticContact ND1-CD2 3.04Å; H131-H139 PolarHBondContact ND1-CD2 2.95Å; H131-H139 AromaticContact ND1-CG 3.9Å; H131-H139 AromaticContact ND1-NE2 3.7Å; H131-H139 PolarHBondContact O-N 2.94Å
132Y97.1Very high95.8Very high5 Ų541.1 Ų41.12%0.0220%0.204CC..EExtended strand (participates in β ladder)trans-112.5142.1173.8-60.7-93000109.9F103 N106 D120 L121 L123 N130 K136 D137F103-Y132 AromaticContact CE1-CD1 3.84Å; F103-Y132 HydrophobicContact CE1-CD1 3.84Å; F103-Y132 HydrophobicContact CE1-CD2 4.15Å; F103-Y132 HydrophobicContact CE1-CE1 4.01Å; F103-Y132 HydrophobicContact CE1-CE2 4.3Å; F103-Y132 AromaticContact CE1-CG 3.91Å; F103-Y132 HydrophobicContact CE1-CG 3.91Å; F103-Y132 AromaticContact CZ-CD1 3.53Å; F103-Y132 HydrophobicContact CZ-CD1 3.53Å; F103-Y132 AromaticContact CZ-CE1 3.53Å; F103-Y132 HydrophobicContact CZ-CE1 3.53Å; F103-Y132 HydrophobicContact CZ-CG 4.09Å; N106-Y132 VanDerWaalsContact CG-OH 3.32Å; N106-Y132 PolarHBondContact N-OH 3.33Å; N106-Y132 PolarHBondContact OD1-OH 3.21Å; D120-Y132 WeakPolarHBondContact CA-O 3.21Å; L121-Y132 PolarHBondContact N-O 3.48Å; L121-Y132 PolarHBondContact O-N 2.92Å; L123-Y132 HydrophobicContact CD1-CD2 3.93Å; L123-Y132 HydrophobicContact CD1-CE2 3.7Å; L123-Y132 HydrophobicContact CG-CD2 4.37Å; L123-Y132 HydrophobicContact CG-CE2 4.43Å; N130-Y132 HydrophobicContact CB-CD2 4.11Å; N130-Y132 HydrophobicContact CB-CE2 3.4Å; Y132-K136 CarbonylContact C-O 3.4Å; Y132-K136 VanDerWaalsContact CA-O 3.28Å; Y132-K136 WeakPolarHBondContact CA-O 3.4Å; Y132-D137 HydrophobicContact CD1-CB 4.1Å; Y132-D137 HydrophobicContact CE1-CB 3.87Å
133C96.2Very high95.6Very high34 Ų3441.4 Ų41.423%0.2321%0.205CC..EExtended strand (participates in β ladder)trans-120.2120167.9-165.70000107.9D120 C135 K136 Q138D120-C133 PolarHBondContact OD1-SG 2.89Å; C133-C135 VanDerWaalsContact C-N 3.29Å; C133-C135 PolarHBondContact O-N 3.48Å; C133-K136 PolarHBondContact N-O 3.05Å; C133-K136 WeakPolarHBondContact O-CB 3.25Å; C133-K136 PolarHBondContact O-N 3.01Å; C133-Q138 HydrophobicContact CB-CG 3.77Å
134D93.3Very high95.3Very high113 Ų11342.9 Ų42.960%0.60422%0.221SC*.THydrogen-bonded Turntrans50.247-173.7-68.3-39.7000113.2S119 K136S119-D134 VanDerWaalsContact CB-OD1 3.29Å; S119-D134 WeakPolarHBondContact CB-OD1 3.49Å; S119-D134 PolarHBondContact O-N 2.79Å; D134-K136 PolarHBondContact O-N 3.42Å; D134-K136 VanDerWaalsContact O-N 3.13Å
135C93.3Very high95.2Very high49 Ų4943.2 Ų43.233%0.33122%0.223SC..THydrogen-bonded Turntrans6116.5-178.1-57.60000114.9F103 C133F103-C135 HydrophobicContact CD1-CB 4.45Å; F103-C135 HydrophobicContact CD2-CB 3.72Å; F103-C135 HydrophobicContact CE1-CB 4.47Å; F103-C135 HydrophobicContact CE2-CB 3.76Å; F103-C135 HydrophobicContact CG-CB 4.1Å; F103-C135 HydrophobicContact CZ-CB 4.15Å; C133-C135 VanDerWaalsContact C-N 3.29Å; C133-C135 PolarHBondContact O-N 3.48Å
136K95.3Very high95.2Very high145 Ų14547.2 Ų47.263%0.6324%0.24SC*.EExtended strand (participates in β ladder)trans-106.3127.9172.6-61.5175.6-175.4171.40109.8Y132 C133 D134 Q138Y132-K136 CarbonylContact C-O 3.4Å; Y132-K136 VanDerWaalsContact CA-O 3.28Å; Y132-K136 WeakPolarHBondContact CA-O 3.4Å; C133-K136 PolarHBondContact N-O 3.05Å; C133-K136 WeakPolarHBondContact O-CB 3.25Å; C133-K136 PolarHBondContact O-N 3.01Å; D134-K136 PolarHBondContact O-N 3.42Å; D134-K136 VanDerWaalsContact O-N 3.13Å; K136-Q138 PolarHBondContact O-N 3.39Å; K136-Q138 PolarHBondContact O-NE2 2.96Å
137D95.4Very high95.5Very high69 Ų6945.9 Ų45.937%0.36923%0.23SC..EExtended strand (participates in β ladder)trans-61.1130.5178.1-158.7-15.8000110.1N106 Y132N106-D137 PolarHBondContact ND2-OD2 2.82Å; Y132-D137 HydrophobicContact CD1-CB 4.1Å; Y132-D137 HydrophobicContact CE1-CB 3.87Å
138Q96.6Very high95.6Very high97 Ų9746.6 Ų46.645%0.45324%0.236SC..EExtended strand (participates in β ladder)trans-118.7-51.2-179.9-62.7-56.9-47.200111H131 C133 K136H131-Q138 PolarHBondContact O-N 3.2Å; C133-Q138 HydrophobicContact CB-CG 3.77Å; K136-Q138 PolarHBondContact O-N 3.39Å; K136-Q138 PolarHBondContact O-NE2 2.96Å
139H97.2Very high95.8Very high58 Ų5845.6 Ų45.627%0.26923%0.23SC..EExtended strand (participates in β ladder)trans-135.6146.7-173.5-49.1-41.1000111N130 H131N130-H139 WeakPolarHBondContact CA-O 3.43Å; H131-H139 HydrophobicContact CB-CB 4.04Å; H131-H139 AromaticContact CE1-CD2 3.97Å; H131-H139 PolarHBondContact N-O 3.13Å; H131-H139 AromaticContact ND1-CD2 3.04Å; H131-H139 PolarHBondContact ND1-CD2 2.95Å; H131-H139 AromaticContact ND1-CG 3.9Å; H131-H139 AromaticContact ND1-NE2 3.7Å; H131-H139 PolarHBondContact O-N 2.94Å
140Y96.2Very high95.8Very high110 Ų11045.6 Ų45.643%0.43123%0.23SC..EExtended strand (participates in β ladder)trans-138.3133.2-178.4170.5-90.4000108.8I128 Y129 L142 S178I128-Y140 HydrophobicContact CB-CE2 4.44Å; I128-Y140 HydrophobicContact CG1-CE2 4.31Å; I128-Y140 HydrophobicContact CG2-CD2 3.95Å; I128-Y140 HydrophobicContact CG2-CE2 3.42Å; I128-Y140 VanDerWaalsContact CG2-CE2 3.42Å; Y129-Y140 WeakPolarHBondContact O-CA 3.44Å; Y140-L142 HydrophobicContact CE1-CB 4.07Å; Y140-S178 PolarHBondContact N-OG 3.35Å; Y140-S178 VanDerWaalsContact O-CB 3.27Å; Y140-S178 WeakPolarHBondContact O-CB 3.34Å; Y140-S178 PolarHBondContact O-OG 2.74Å
141Y96.1Very high95.9Very high40 Ų4046 Ų4616%0.15723%0.233CC..EExtended strand (participates in β ladder)trans-136.2135.4173.4176.9-108.4000110.2Y129 L165 L175 S178 V180Y129-Y141 PolarHBondContact N-O 3.15Å; Y129-Y141 PolarHBondContact O-N 3.32Å; Y141-L165 HydrophobicContact CD1-CD1 3.63Å; Y141-L165 HydrophobicContact CE1-CD1 3.98Å; Y141-L175 HydrophobicContact CD1-CD1 4.21Å; Y141-L175 HydrophobicContact CG-CD1 4.25Å; Y141-S178 WeakPolarHBondContact CD2-O 3.49Å; Y141-V180 HydrophobicContact CE1-CG2 4.44Å; Y141-V180 HydrophobicContact CE2-CG2 3.64Å; Y141-V180 WeakPolarHBondContact OH-CG2 3.44Å
142L94.6Very high95.9Very high66 Ų6646 Ų4635%0.34623%0.232SC..EExtended strand (participates in β ladder)trans-106.6105.3172.9-177.966.6000108.9I128 Y140I128-L142 HydrophobicContact CG1-CD1 3.87Å; Y140-L142 HydrophobicContact CE1-CB 4.07Å
143S93.9Very high95.8Very high5 Ų545.7 Ų45.74%0.03523%0.231CC..  trans-69.1142.6178.1179.90000111.5Y127 D145 R173Y127-S143 WeakPolarHBondContact O-CB 3.27Å; Y127-S143 PolarHBondContact O-N 3.06Å; S143-D145 WeakPolarHBondContact CB-O 3.48Å; S143-D145 PolarHBondContact O-N 2.86Å; S143-D145 PolarHBondContact OG-N 3.43Å; S143-D145 PolarHBondContact OG-O 3.11Å; S143-R173 PolarHBondContact OG-NH1 2.94Å
144G90.3Very high95.7Very high32 Ų3244.6 Ų44.633%0.3322%0.224SC..SBendtrans-69-17.5173.100000113.7
145D94Very high95.6Very high8 Ų840.6 Ų40.64%0.04320%0.203CC..SBendtrans-136.9170.3176-141.3-54.2000111.7Y127 S143 D169 R496Y127-D145 VanDerWaalsContact CD1-C 3.47Å; S143-D145 WeakPolarHBondContact CB-O 3.48Å; S143-D145 PolarHBondContact O-N 2.86Å; S143-D145 PolarHBondContact OG-N 3.43Å; S143-D145 PolarHBondContact OG-O 3.11Å; D145-D169 HydrophobicContact CB-CB 3.97Å; D145-D169 WeakPolarHBondContact OD2-CB 3.2Å; D145-R496 IonicContact OD2-CZ 3.76Å; D145-R496 IonicContact OD2-NH1 2.83Å; D145-R496 PolarHBondContact OD2-NH1 2.85Å
146K95.8Very high95.3Very high84 Ų8442.8 Ų42.837%0.36521%0.209SC..  trans-62.4140.6-176.7-67.8178-178.1172.10111.4S126 Y127 C167 Q168S126-K146 CarbonylContact O-C 3.54Å; S126-K146 WeakPolarHBondContact O-CA 3.31Å; Y127-K146 HydrophobicContact CD1-CG 4.39Å; Y127-K146 HydrophobicContact CE1-CG 3.71Å; Y127-K146 HydrophobicContact CE2-CG 4.04Å; Y127-K146 WeakPolarHBondContact OH-CE 3.42Å; K146-C167 CarbonylContact O-C 3.5Å; K146-C167 VanDerWaalsContact O-CA 3.29Å; K146-C167 WeakPolarHBondContact O-CA 3.42Å; K146-Q168 HydrophobicContact CB-CB 3.99Å; K146-Q168 PolarHBondContact O-N 2.7Å
147I97.8Very high95Very high5 Ų540.8 Ų40.83%0.02620%0.197CC..EExtended strand (participates in β ladder)trans-96.1123.2175.9-55.6168000108.8S126 L165 A166S126-I147 PolarHBondContact O-N 3Å; I147-L165 HydrophobicContact CD1-CD1 4.03Å; I147-L165 HydrophobicContact CG2-CB 4.42Å; I147-L165 HydrophobicContact CG2-CD2 4.45Å; I147-A166 WeakPolarHBondContact CA-O 3.4Å
148N97.9Very high94.6Very high34 Ų3438.6 Ų38.618%0.18219%0.185CC..EExtended strand (participates in β ladder)trans-94.7-40.3-177.3-69.5-22.5000112.8A166 Q168 P190N148-A166 PolarHBondContact N-O 3.4Å; N148-Q168 PolarHBondContact ND2-OE1 3.38Å; N148-Q168 PolarHBondContact OD1-OE1 2.91Å; N148-P190 WeakPolarHBondContact CB-O 3.49Å; N148-P190 PolarHBondContact ND2-O 3.3Å
149D98.6Very high94.1Very high0 Ų039.6 Ų39.60%020%0.203CC..EExtended strand (participates in β ladder)trans-148.8159.1176.6-1545.4000110.7K19 A166 L193K19-D149 IonicContact NZ-OD1 3.15Å; K19-D149 IonicContact NZ-OD2 3.47Å; K19-D149 PolarHBondContact NZ-OD2 3.16Å; D149-A166 HydrophobicContact CB-CB 4.27Å; D149-A166 PolarHBondContact O-N 3.36Å; D149-L193 HydrophobicContact CB-CG 4.31Å; D149-L193 PolarHBondContact OD2-N 2.9Å
150V98.4Very high93.8Very high1 Ų139.6 Ų39.61%0.00620%0.201CC..EExtended strand (participates in β ladder)trans-134.6138.9175.8610000109.8A113 H115 F122 Y129 L165A113-V150 HydrophobicContact CB-CG1 3.93Å; H115-V150 HydrophobicContact CB-CG1 4.5Å; H115-V150 WeakPolarHBondContact CB-O 3.43Å; F122-V150 HydrophobicContact CB-CG2 4.02Å; Y129-V150 HydrophobicContact CD2-CG2 4.11Å; Y129-V150 HydrophobicContact CE2-CG2 3.86Å; V150-L165 HydrophobicContact CB-CD2 4.01Å; V150-L165 HydrophobicContact CG2-CD2 3.59Å
151I97.9Very high93.7Very high9 Ų936.7 Ų36.75%0.04619%0.192CC..EExtended strand (participates in β ladder)trans-144.2155.2173.7-159.5164.6000109.8P163 V164 L193 L195 L207I151-P163 CarbonylContact O-C 3.52Å; I151-P163 WeakPolarHBondContact O-CA 3.4Å; I151-V164 HydrophobicContact CG2-CB 4.12Å; I151-V164 PolarHBondContact N-O 2.9Å; I151-V164 VanDerWaalsContact N-O 3.13Å; I151-V164 PolarHBondContact O-N 3.07Å; I151-L193 HydrophobicContact CB-CB 4.18Å; I151-L193 HydrophobicContact CB-CD1 4.47Å; I151-L193 HydrophobicContact CD1-CB 4.44Å; I151-L193 HydrophobicContact CG2-CB 3.89Å; I151-L193 HydrophobicContact CG2-CD1 3.77Å; I151-L193 HydrophobicContact CG2-CG 4.49Å; I151-L195 HydrophobicContact CD1-CD2 4.2Å; I151-L195 HydrophobicContact CD1-CG 3.83Å; I151-L195 HydrophobicContact CG1-CG 4.37Å; I151-L207 HydrophobicContact CD1-CD1 4.28Å; I151-L207 HydrophobicContact CG2-CD1 3.61Å
152C97.4Very high93.7Very high1 Ų135.1 Ų35.11%0.00719%0.187CC..EExtended strand (participates in β ladder)trans-114.8138.7171.3-169.20000109.1H115 F122H115-C152 PolarHBondContact CD2-N 2.79Å; H115-C152 VanDerWaalsContact CD2-N 3.26Å; F122-C152 HydrophobicContact CD2-CB 3.83Å; F122-C152 HydrophobicContact CE2-CB 3.5Å; F122-C152 VanDerWaalsContact CE2-CB 3.5Å; F122-C152 HydrophobicContact CZ-CB 3.92Å
153L96.5Very high93.9Very high0 Ų032 Ų320%017%0.171CC..  trans-61.9149.6169.4-63.5-177000110.4V155 L158 T162 L195 I221L153-V155 PolarHBondContact O-N 3.44Å; L153-L158 HydrophobicContact CB-CD1 3.57Å; L153-L158 HydrophobicContact CD1-CD1 3.65Å; L153-L158 HydrophobicContact CG-CD1 4.24Å; L153-T162 HydrophobicContact CD1-CG2 3.89Å; L153-T162 HydrophobicContact CG-CG2 4.4Å; L153-T162 PolarHBondContact N-O 3.15Å; L153-L195 HydrophobicContact CD2-CD2 4.03Å; L153-I221 HydrophobicContact CD1-CB 4.03Å; L153-I221 HydrophobicContact CD1-CG2 4Å
154P93.8Very high94.1Very high11 Ų1131.8 Ų31.87%0.07117%0.169CC..  trans-60.9103.2-175.826-38000112.1E156 R157 L158 N199 G204P154-E156 PolarHBondContact O-N 3.38Å; P154-R157 HydrophobicContact CB-CB 4.42Å; P154-R157 HydrophobicContact CB-CG 4.34Å; P154-R157 HydrophobicContact CG-CB 4.31Å; P154-R157 HydrophobicContact CG-CG 4.5Å; P154-R157 PolarHBondContact O-N 2.88Å; P154-L158 PolarHBondContact O-N 2.67Å; P154-N199 WeakPolarHBondContact CG-O 3.08Å; P154-G204 WeakPolarHBondContact CD-O 3.47Å; P154-G204 WeakPolarHBondContact CG-O 3.27Å
155V90.7Very high94.5Very high29 Ų2930.3 Ų30.318%0.17615%0.153CC..Hα-helixtrans-58.8-33.3-179.7-173.30000111.6L153 R157 S159 I161L153-V155 PolarHBondContact O-N 3.44Å; V155-R157 PolarHBondContact O-N 3.44Å; V155-S159 WeakPolarHBondContact O-CA 3.35Å; V155-S159 PolarHBondContact O-N 2.99Å; V155-I161 HydrophobicContact CG1-CG1 4.33Å; V155-I161 HydrophobicContact CG2-CG1 3.99Å
156E87.3Confident94.7Very high95 Ų9529.9 Ų29.944%0.44415%0.151SC..Hα-helixtrans-60.4-26.6177.7-61.4160.9163.400112.8L75 N76 P154L75-E156 VanDerWaalsContact CA-OE1 3.29Å; L75-E156 WeakPolarHBondContact CA-OE1 3.26Å; L75-E156 HydrophobicContact CB-CG 4.24Å; L75-E156 VanDerWaalsContact CB-OE1 3.32Å; L75-E156 WeakPolarHBondContact CB-OE1 3.32Å; L75-E156 HydrophobicContact CD2-CG 3.97Å; L75-E156 VanDerWaalsContact CD2-OE1 3.28Å; L75-E156 WeakPolarHBondContact CD2-OE1 3.39Å; L75-E156 HydrophobicContact CG-CG 4.45Å; N76-E156 PolarHBondContact N-OE1 2.73Å; P154-E156 PolarHBondContact O-N 3.38Å
157R89.4Confident94.8Very high103 Ų10325.9 Ų25.939%0.38913%0.134SC..Hα-helixtrans-103.6-35.4-178.1-61.5-175.273.1166.14.9113.1P154 V155 N199 G201 D202P154-R157 HydrophobicContact CB-CB 4.42Å; P154-R157 HydrophobicContact CB-CG 4.34Å; P154-R157 HydrophobicContact CG-CB 4.31Å; P154-R157 HydrophobicContact CG-CG 4.5Å; P154-R157 PolarHBondContact O-N 2.88Å; V155-R157 PolarHBondContact O-N 3.44Å; R157-N199 WeakPolarHBondContact CD-O 3.34Å; R157-N199 PolarHBondContact NH1-ND2 2.95Å; R157-N199 PolarHBondContact NH1-O 3.41Å; R157-G201 PolarHBondContact NH1-O 3.3Å; R157-G201 PolarHBondContact NH2-O 3.03Å; R157-D202 PolarHBondContact NH2-O 3.22Å
158L87.4Confident94.7Very high22 Ų2229 Ų2912%0.11515%0.149CC..Hα-helixtrans-98.6-10.2-173.8-58.5-176.2000114.1L153 P154 R160 S203 E205L153-L158 HydrophobicContact CB-CD1 3.57Å; L153-L158 HydrophobicContact CD1-CD1 3.65Å; L153-L158 HydrophobicContact CG-CD1 4.24Å; P154-L158 PolarHBondContact O-N 2.67Å; L158-R160 HydrophobicContact CB-CG 3.98Å; L158-R160 PolarHBondContact O-N 2.6Å; L158-S203 WeakPolarHBondContact CD2-O 3.5Å; L158-E205 HydrophobicContact CD1-CG 3.83Å; L158-E205 HydrophobicContact CD2-CG 3.53Å; L158-E205 HydrophobicContact CG-CG 4.34Å
159S85.1Confident94.6Very high119 Ų11928 Ų2883%0.83214%0.143SC*.SBendtrans55.515.9-176.866.60000115.2V155V155-S159 WeakPolarHBondContact O-CA 3.35Å; V155-S159 PolarHBondContact O-N 2.99Å
160R90.1Very high94.5Very high57 Ų5728.8 Ų28.822%0.21515%0.146CC..SBendtrans-140.1150.4177.962.6-179.8172.3166.5-1.4110L158 E205L158-R160 HydrophobicContact CB-CG 3.98Å; L158-R160 PolarHBondContact O-N 2.6Å; R160-E205 IonicContact NH2-OE1 2.74Å; R160-E205 PolarHBondContact NH2-OE1 2.93Å
161I94.7Very high94.4Very high50 Ų5029 Ų2926%0.25615%0.147SC..  trans-89.1115.5172-63.5174.3000107.4F122 V155 P163F122-I161 HydrophobicContact CE1-CG2 3.68Å; F122-I161 HydrophobicContact CZ-CG2 3.61Å; V155-I161 HydrophobicContact CG1-CG1 4.33Å; V155-I161 HydrophobicContact CG2-CG1 3.99Å; I161-P163 HydrophobicContact CG2-CG 4.28Å
162T96.5Very high94.4Very high7 Ų728.6 Ų28.64%0.04315%0.145CC..  trans-128.787.7178.6-57.40000108.2L153 V174L153-T162 HydrophobicContact CD1-CG2 3.89Å; L153-T162 HydrophobicContact CG-CG2 4.4Å; L153-T162 PolarHBondContact N-O 3.15Å; T162-V174 HydrophobicContact CG2-CG1 3.63Å
163P97.7Very high94.5Very high1 Ų129.2 Ų29.21%0.00615%0.147CC..EExtended strand (participates in β ladder)trans-72.6145.3173.45.59.7000110.2F122 Y129 I151 I161 L175F122-P163 HydrophobicContact CD1-CB 4.45Å; F122-P163 HydrophobicContact CE1-CG 4.33Å; Y129-P163 HydrophobicContact CE2-CB 4.28Å; Y129-P163 VanDerWaalsContact OH-CB 3.22Å; Y129-P163 WeakPolarHBondContact OH-CB 2.99Å; Y129-P163 WeakPolarHBondContact OH-CG 3.33Å; I151-P163 CarbonylContact O-C 3.52Å; I151-P163 WeakPolarHBondContact O-CA 3.4Å; I161-P163 HydrophobicContact CG2-CG 4.28Å; P163-L175 HydrophobicContact CB-CB 4.47Å; P163-L175 VanDerWaalsContact CD-O 3.3Å; P163-L175 WeakPolarHBondContact CD-O 3.23Å; P163-L175 HydrophobicContact CG-CB 4.09Å; P163-L175 PolarHBondContact O-N 2.92Å
164V98.5Very high94.5Very high0 Ų029.3 Ų29.30%015%0.148CC..EExtended strand (participates in β ladder)trans-126.2126.3176.2-171.90000108I151 L172 R173 V174 L193 L207 I221I151-V164 HydrophobicContact CG2-CB 4.12Å; I151-V164 PolarHBondContact N-O 2.9Å; I151-V164 VanDerWaalsContact N-O 3.13Å; I151-V164 PolarHBondContact O-N 3.07Å; V164-L172 HydrophobicContact CG1-CB 4.16Å; V164-R173 WeakPolarHBondContact CA-O 3.22Å; V164-V174 HydrophobicContact CG1-CG2 4.49Å; V164-L193 HydrophobicContact CG1-CD1 4.33Å; V164-L207 HydrophobicContact CB-CD2 4.25Å; V164-L207 HydrophobicContact CG1-CD2 3.8Å; V164-L207 HydrophobicContact CG2-CD2 4.39Å; V164-I221 HydrophobicContact CB-CD1 4.41Å; V164-I221 HydrophobicContact CG1-CD1 4.11Å; V164-I221 HydrophobicContact CG2-CD1 3.5Å
165L98.6Very high94.7Very high0 Ų028.8 Ų28.80%014%0.144CC..EExtended strand (participates in β ladder)trans-103.7126.4177.8-53.4-176.2000109.8Y129 Y141 I147 V150 L172 R173 L175Y129-L165 HydrophobicContact CD2-CD2 3.55Å; Y129-L165 HydrophobicContact CE2-CD2 4.02Å; Y129-L165 HydrophobicContact CG-CD1 4.2Å; Y129-L165 HydrophobicContact CG-CD2 4.02Å; Y141-L165 HydrophobicContact CD1-CD1 3.63Å; Y141-L165 HydrophobicContact CE1-CD1 3.98Å; I147-L165 HydrophobicContact CD1-CD1 4.03Å; I147-L165 HydrophobicContact CG2-CB 4.42Å; I147-L165 HydrophobicContact CG2-CD2 4.45Å; V150-L165 HydrophobicContact CB-CD2 4.01Å; V150-L165 HydrophobicContact CG2-CD2 3.59Å; L165-L172 CarbonylContact O-C 3.6Å; L165-L172 VanDerWaalsContact O-CA 3.31Å; L165-L172 WeakPolarHBondContact O-CA 3.45Å; L165-R173 HydrophobicContact CB-CB 4.31Å; L165-R173 PolarHBondContact N-O 3.2Å; L165-R173 PolarHBondContact O-N 2.82Å; L165-L175 HydrophobicContact CD1-CD1 3.65Å; L165-L175 HydrophobicContact CD1-CG 4.34Å; L165-L175 HydrophobicContact CG-CD1 3.96Å; L165-L175 HydrophobicContact CG-CG 4.37Å
166A98.4Very high94.9Very high0 Ų032.4 Ų32.40%016%0.16CC..EExtended strand (participates in β ladder)trans-85115.4167.100000109.1I147 N148 D149 L172 P190 L193I147-A166 WeakPolarHBondContact CA-O 3.4Å; N148-A166 PolarHBondContact N-O 3.4Å; D149-A166 HydrophobicContact CB-CB 4.27Å; D149-A166 PolarHBondContact O-N 3.36Å; A166-L172 HydrophobicContact CB-CD2 3.99Å; A166-P190 HydrophobicContact CB-CB 3.8Å; A166-P190 HydrophobicContact CB-CG 3.78Å; A166-L193 HydrophobicContact CB-CD1 3.8Å; A166-L193 HydrophobicContact CB-CD2 4.13Å; A166-L193 HydrophobicContact CB-CG 3.86Å
167C97.7Very high95.2Very high0 Ų028.7 Ų28.70%015%0.147CC..EExtended strand (participates in β ladder)trans-111.3146-177.1-62.30000112.4K146 D169 R170 V171 R173 P190K146-C167 CarbonylContact O-C 3.5Å; K146-C167 VanDerWaalsContact O-CA 3.29Å; K146-C167 WeakPolarHBondContact O-CA 3.42Å; C167-D169 WeakPolarHBondContact CB-OD1 3.37Å; C167-D169 PolarHBondContact O-N 3.23Å; C167-D169 VanDerWaalsContact O-N 3.09Å; C167-R170 PolarHBondContact O-N 2.89Å; C167-V171 PolarHBondContact N-O 3.31Å; C167-R173 PolarHBondContact SG-NH1 2.91Å; C167-P190 VanDerWaalsContact O-CD 3.23Å; C167-P190 WeakPolarHBondContact O-CD 3.25Å; C167-P190 WeakPolarHBondContact O-CG 3.43Å
168Q96.4Very high95.5Very high71 Ų7126 Ų2633%0.33214%0.143SC..THydrogen-bonded Turntrans-61.8-21.1-172.4-176.261.339.200113.8K146 N148 R170K146-Q168 HydrophobicContact CB-CB 3.99Å; K146-Q168 PolarHBondContact O-N 2.7Å; N148-Q168 PolarHBondContact ND2-OE1 3.38Å; N148-Q168 PolarHBondContact OD1-OE1 2.91Å; Q168-R170 PolarHBondContact O-N 3.36Å
169D94.8Very high95.9Very high11 Ų1130.8 Ų30.86%0.05917%0.169CC..THydrogen-bonded Turntrans-80.519.7177.355.3-14.3000114.7D145 C167 V171 R173 R496 H498D145-D169 HydrophobicContact CB-CB 3.97Å; D145-D169 WeakPolarHBondContact OD2-CB 3.2Å; C167-D169 WeakPolarHBondContact CB-OD1 3.37Å; C167-D169 PolarHBondContact O-N 3.23Å; C167-D169 VanDerWaalsContact O-N 3.09Å; D169-V171 VanDerWaalsContact C-N 3.32Å; D169-R173 IonicContact OD1-CZ 3.63Å; D169-R173 IonicContact OD1-NH1 3.62Å; D169-R173 PolarHBondContact OD1-NH1 2.83Å; D169-R173 IonicContact OD1-NH2 2.7Å; D169-R173 IonicContact OD2-CZ 3.47Å; D169-R173 IonicContact OD2-NH1 2.72Å; D169-R173 IonicContact OD2-NH2 3.63Å; D169-R173 PolarHBondContact OD2-NH2 3.05Å; D169-R496 VanDerWaalsContact CB-CZ 3.48Å; D169-R496 IonicContact OD2-NH2 3.78Å; D169-R496 PolarHBondContact OD2-NH2 2.95Å; D169-H498 PolarHBondContact O-CE1 3.41Å
170R96.8Very high96.4Very high18 Ų1827.6 Ų27.67%0.06815%0.145CC..THydrogen-bonded Turntrans66.833.2177.2-39-175.5-170.5159.317.9113.4C167 Q168 V186 P189 Q495 R496 H498 E530C167-R170 PolarHBondContact O-N 2.89Å; Q168-R170 PolarHBondContact O-N 3.36Å; R170-V186 VanDerWaalsContact C-CG2 3.45Å; R170-V186 HydrophobicContact CB-CG2 4.36Å; R170-V186 WeakPolarHBondContact CB-O 3.38Å; R170-V186 WeakPolarHBondContact O-CG2 3.35Å; R170-V186 PolarHBondContact O-N 3.45Å; R170-P189 HydrophobicContact CG-CG 4.12Å; R170-Q495 VanDerWaalsContact NH2-NE2 3.16Å; R170-R496 PolarHBondContact NH1-O 2.84Å; R170-R496 PolarHBondContact NH2-O 3.18Å; R170-H498 PolarHBondContact O-CE1 2.82Å; R170-H498 PolarHBondContact O-NE2 3.33Å; R170-E530 IonicContact CZ-OE2 3.24Å; R170-E530 IonicContact NE-OE2 3.31Å; R170-E530 IonicContact NH2-OE1 3.92Å; R170-E530 IonicContact NH2-OE2 3.42Å; R170-E530 PolarHBondContact NH2-OE2 3.23Å
171V97.2Very high96.7Very high5 Ų528.6 Ų28.63%0.0315%0.153CC..EExtended strand (participates in β ladder)trans-124.5137.4178.5177.70000109.9C167 D169 R173 E183 I184C167-V171 PolarHBondContact N-O 3.31Å; D169-V171 VanDerWaalsContact C-N 3.32Å; V171-R173 HydrophobicContact CG1-CG 3.93Å; V171-E183 HydrophobicContact CG1-CB 3.58Å; V171-E183 HydrophobicContact CG1-CG 3.82Å; V171-I184 CarbonylContact C-O 3.25Å; V171-I184 WeakPolarHBondContact CA-O 3.45Å
172L98.4Very high96.8Very high0 Ų027.8 Ų27.80%015%0.147CC..EExtended strand (participates in β ladder)trans-95118.7159.8-52.3178.7000108.6V164 L165 A166 I184 V186 P190 L193 L207 F209 I219V164-L172 HydrophobicContact CG1-CB 4.16Å; L165-L172 CarbonylContact O-C 3.6Å; L165-L172 VanDerWaalsContact O-CA 3.31Å; L165-L172 WeakPolarHBondContact O-CA 3.45Å; A166-L172 HydrophobicContact CB-CD2 3.99Å; L172-I184 HydrophobicContact CB-CB 4.15Å; L172-I184 HydrophobicContact CB-CD1 4.34Å; L172-I184 PolarHBondContact N-O 3.13Å; L172-I184 PolarHBondContact O-N 3.04Å; L172-V186 HydrophobicContact CD1-CG1 4Å; L172-V186 HydrophobicContact CG-CG1 3.98Å; L172-P190 HydrophobicContact CD2-CB 3.78Å; L172-P190 HydrophobicContact CD2-CG 3.7Å; L172-L193 HydrophobicContact CD2-CD2 3.92Å; L172-L207 HydrophobicContact CD1-CD2 4.3Å; L172-F209 HydrophobicContact CD1-CB 4.33Å; L172-F209 HydrophobicContact CD1-CG 4.44Å; L172-I219 HydrophobicContact CD1-CD1 4.01Å
173R97.9Very high96.8Very high14 Ų1432.2 Ų32.25%0.05317%0.167CC..EExtended strand (participates in β ladder)trans-94.9114.1177.5-61.1-176.116699.913.5109.1S143 V164 L165 C167 D169 V171 E183S143-R173 PolarHBondContact OG-NH1 2.94Å; V164-R173 WeakPolarHBondContact CA-O 3.22Å; L165-R173 HydrophobicContact CB-CB 4.31Å; L165-R173 PolarHBondContact N-O 3.2Å; L165-R173 PolarHBondContact O-N 2.82Å; C167-R173 PolarHBondContact SG-NH1 2.91Å; D169-R173 IonicContact OD1-CZ 3.63Å; D169-R173 IonicContact OD1-NH1 3.62Å; D169-R173 PolarHBondContact OD1-NH1 2.83Å; D169-R173 IonicContact OD1-NH2 2.7Å; D169-R173 IonicContact OD2-CZ 3.47Å; D169-R173 IonicContact OD2-NH1 2.72Å; D169-R173 IonicContact OD2-NH2 3.63Å; D169-R173 PolarHBondContact OD2-NH2 3.05Å; V171-R173 HydrophobicContact CG1-CG 3.93Å; R173-E183 HydrophobicContact CG-CG 4.26Å; R173-E183 IonicContact CZ-OE1 2.74Å; R173-E183 IonicContact NE-OE1 2.84Å; R173-E183 PolarHBondContact NE-OE1 3.37Å; R173-E183 IonicContact NH2-OE1 2.69Å; R173-E183 PolarHBondContact NH2-OE1 3.31Å
174V98Very high96.8Very high2 Ų232.3 Ų32.31%0.01217%0.167CC..EExtended strand (participates in β ladder)trans-88.6120.6176.2-175.90000107.7T162 V164 M181 Y182 I184 I221T162-V174 HydrophobicContact CG2-CG1 3.63Å; V164-V174 HydrophobicContact CG1-CG2 4.49Å; V174-M181 HydrophobicContact CG1-CB 4.45Å; V174-M181 WeakPolarHBondContact O-CB 3.5Å; V174-M181 PolarHBondContact O-N 2.81Å; V174-Y182 HydrophobicContact CB-CE1 4.39Å; V174-Y182 HydrophobicContact CB-CE2 4.31Å; V174-Y182 HydrophobicContact CG1-CE1 4.31Å; V174-Y182 HydrophobicContact CG2-CD2 4.26Å; V174-Y182 HydrophobicContact CG2-CE2 3.76Å; V174-Y182 PolarHBondContact N-O 2.97Å; V174-Y182 VanDerWaalsContact N-O 3.09Å; V174-I184 HydrophobicContact CG2-CD1 3.68Å; V174-I184 HydrophobicContact CG2-CG1 4.21Å; V174-I221 HydrophobicContact CG1-CG2 3.78Å; V174-I221 HydrophobicContact CG2-CD1 4.36Å; V174-I221 HydrophobicContact CG2-CG2 3.92Å
175L97.1Very high96.7Very high0 Ų037.1 Ų37.10%019%0.19CC..EExtended strand (participates in β ladder)trans-104.3156.9-176.7-59-172.8000111.8Y129 Y141 P163 L165 D179 V180Y129-L175 HydrophobicContact CD1-CD1 3.87Å; Y129-L175 HydrophobicContact CE1-CD1 3.81Å; Y129-L175 HydrophobicContact CG-CD1 4.45Å; Y141-L175 HydrophobicContact CD1-CD1 4.21Å; Y141-L175 HydrophobicContact CG-CD1 4.25Å; P163-L175 HydrophobicContact CB-CB 4.47Å; P163-L175 VanDerWaalsContact CD-O 3.3Å; P163-L175 WeakPolarHBondContact CD-O 3.23Å; P163-L175 HydrophobicContact CG-CB 4.09Å; P163-L175 PolarHBondContact O-N 2.92Å; L165-L175 HydrophobicContact CD1-CD1 3.65Å; L165-L175 HydrophobicContact CD1-CG 4.34Å; L165-L175 HydrophobicContact CG-CD1 3.96Å; L165-L175 HydrophobicContact CG-CG 4.37Å; L175-D179 WeakPolarHBondContact CA-O 3.46Å; L175-V180 HydrophobicContact CD2-CB 4.07Å; L175-V180 HydrophobicContact CD2-CG2 3.5Å; L175-V180 VanDerWaalsContact CD2-CG2 3.5Å
176Q94.4Very high96.6Very high106 Ų10637.4 Ų37.450%0.49519%0.192SC..EExtended strand (participates in β ladder)trans-136.8114.9158.5-175.8175.26.100108S178 D179 M181Q176-S178 PolarHBondContact O-N 2.9Å; Q176-D179 PolarHBondContact N-O 3.39Å; Q176-D179 PolarHBondContact O-N 3.47Å; Q176-M181 HydrophobicContact CB-CG 3.67Å; Q176-M181 HydrophobicContact CB-SD 3.78Å; Q176-M181 PolarHBondContact OE1-SD 2.87Å
177G93.6Very high96.3Very high17 Ų1739.6 Ų39.618%0.17521%0.205CC..THydrogen-bonded Turntrans66.4-123.9-169.500000111.3
178S96.3Very high96.1Very high45 Ų4539.6 Ų39.632%0.31521%0.205SC..THydrogen-bonded Turntrans-96.8-3.9177.5-60.70000113.7Y140 Y141 Q176Y140-S178 PolarHBondContact N-OG 3.35Å; Y140-S178 VanDerWaalsContact O-CB 3.27Å; Y140-S178 WeakPolarHBondContact O-CB 3.34Å; Y140-S178 PolarHBondContact O-OG 2.74Å; Y141-S178 WeakPolarHBondContact CD2-O 3.49Å; Q176-S178 PolarHBondContact O-N 2.9Å
179D95.1Very high96.1Very high123 Ų12336.5 Ų36.566%0.65819%0.192SC*.EExtended strand (participates in β ladder)trans-107.3145.4-171.1-61.5-56.6000111.9L175 Q176L175-D179 WeakPolarHBondContact CA-O 3.46Å; Q176-D179 PolarHBondContact N-O 3.39Å; Q176-D179 PolarHBondContact O-N 3.47Å
180V96.3Very high96.3Very high53 Ų5336 Ų3632%0.32119%0.189SC..EExtended strand (participates in β ladder)trans-78.3120.6173.8-178.30000109.2Y141 L175 E183Y141-V180 HydrophobicContact CE1-CG2 4.44Å; Y141-V180 HydrophobicContact CE2-CG2 3.64Å; Y141-V180 WeakPolarHBondContact OH-CG2 3.44Å; L175-V180 HydrophobicContact CD2-CB 4.07Å; L175-V180 HydrophobicContact CD2-CG2 3.5Å; L175-V180 VanDerWaalsContact CD2-CG2 3.5Å; V180-E183 HydrophobicContact CG1-CG 4.04Å
181M95.9Very high96.3Very high78 Ų7836.1 Ų36.138%0.38419%0.192SC..EExtended strand (participates in β ladder)trans-71.2-54.8174.1-74.8-84.3-50.300110.9V174 Q176 T223V174-M181 HydrophobicContact CG1-CB 4.45Å; V174-M181 WeakPolarHBondContact O-CB 3.5Å; V174-M181 PolarHBondContact O-N 2.81Å; Q176-M181 HydrophobicContact CB-CG 3.67Å; Q176-M181 HydrophobicContact CB-SD 3.78Å; Q176-M181 PolarHBondContact OE1-SD 2.87Å; M181-T223 WeakPolarHBondContact CE-O 3.36Å
182Y97Very high96.4Very high32 Ų3235.9 Ų35.913%0.12519%0.19CC..EExtended strand (participates in β ladder)trans-164.1164.8176.260.3-93.1000109.8V174 I184 I221 T222 P226V174-Y182 HydrophobicContact CB-CE1 4.39Å; V174-Y182 HydrophobicContact CB-CE2 4.31Å; V174-Y182 HydrophobicContact CG1-CE1 4.31Å; V174-Y182 HydrophobicContact CG2-CD2 4.26Å; V174-Y182 HydrophobicContact CG2-CE2 3.76Å; V174-Y182 PolarHBondContact N-O 2.97Å; V174-Y182 VanDerWaalsContact N-O 3.09Å; Y182-I184 HydrophobicContact CD2-CG1 3.94Å; Y182-I184 HydrophobicContact CE2-CD1 3.88Å; Y182-I184 HydrophobicContact CE2-CG1 3.65Å; Y182-I221 VanDerWaalsContact OH-CG2 3.25Å; Y182-I221 WeakPolarHBondContact OH-CG2 3.3Å; Y182-T222 PolarHBondContact OH-N 3.1Å; Y182-T222 PolarHBondContact OH-O 2.75Å; Y182-P226 HydrophobicContact CE2-CB 4.4Å; Y182-P226 HydrophobicContact CE2-CG 4.38Å
183E96.8Very high96.4Very high101 Ų10136 Ų3647%0.47219%0.191SC..EExtended strand (participates in β ladder)trans-108.6147.3178.8-68.1-165.7147.800110.1V171 R173 V180V171-E183 HydrophobicContact CG1-CB 3.58Å; V171-E183 HydrophobicContact CG1-CG 3.82Å; R173-E183 HydrophobicContact CG-CG 4.26Å; R173-E183 IonicContact CZ-OE1 2.74Å; R173-E183 IonicContact NE-OE1 2.84Å; R173-E183 PolarHBondContact NE-OE1 3.37Å; R173-E183 IonicContact NH2-OE1 2.69Å; R173-E183 PolarHBondContact NH2-OE1 3.31Å; V180-E183 HydrophobicContact CG1-CG 4.04Å
184I97.7Very high96.4Very high2 Ų236 Ų361%0.0119%0.194CC..EExtended strand (participates in β ladder)trans-122.5121177.4-45.9166.6000108.3V171 L172 V174 Y182 I219 I221 P226V171-I184 CarbonylContact C-O 3.25Å; V171-I184 WeakPolarHBondContact CA-O 3.45Å; L172-I184 HydrophobicContact CB-CB 4.15Å; L172-I184 HydrophobicContact CB-CD1 4.34Å; L172-I184 PolarHBondContact N-O 3.13Å; L172-I184 PolarHBondContact O-N 3.04Å; V174-I184 HydrophobicContact CG2-CD1 3.68Å; V174-I184 HydrophobicContact CG2-CG1 4.21Å; Y182-I184 HydrophobicContact CD2-CG1 3.94Å; Y182-I184 HydrophobicContact CE2-CD1 3.88Å; Y182-I184 HydrophobicContact CE2-CG1 3.65Å; I184-I219 HydrophobicContact CD1-CG2 4.19Å; I184-I219 HydrophobicContact CG2-CD1 3.96Å; I184-I219 HydrophobicContact CG2-CG2 4.47Å; I184-I221 HydrophobicContact CD1-CD1 4.42Å; I184-I221 HydrophobicContact CD1-CG1 4.22Å; I184-P226 HydrophobicContact CB-CB 4.41Å; I184-P226 HydrophobicContact CB-CG 4.4Å; I184-P226 HydrophobicContact CD1-CB 3.87Å; I184-P226 HydrophobicContact CG1-CB 3.82Å; I184-P226 HydrophobicContact CG1-CG 3.96Å; I184-P226 HydrophobicContact CG2-CB 3.77Å; I184-P226 HydrophobicContact CG2-CG 3.87Å
185E95.9Very high96.3Very high102 Ų10237 Ų3748%0.47720%0.199SC..EExtended strand (participates in β ladder)trans-74.6135.5176.4-61.1179.2-172.600110.3H498E185-H498 HydrophobicContact CG-CB 4.3Å; E185-H498 WeakPolarHBondContact OE1-CB 3.4Å; E185-H498 IonicContact OE1-CG 3.44Å; E185-H498 IonicContact OE2-CD2 2.9Å; E185-H498 IonicContact OE2-CG 2.8Å
186V96.2Very high96.2Very high6 Ų638.2 Ų38.24%0.03621%0.205CC..  trans-127151.9174.9-70.70000110.3R170 L172 G188 P190 F209 I219R170-V186 VanDerWaalsContact C-CG2 3.45Å; R170-V186 HydrophobicContact CB-CG2 4.36Å; R170-V186 WeakPolarHBondContact CB-O 3.38Å; R170-V186 WeakPolarHBondContact O-CG2 3.35Å; R170-V186 PolarHBondContact O-N 3.45Å; L172-V186 HydrophobicContact CD1-CG1 4Å; L172-V186 HydrophobicContact CG-CG1 3.98Å; V186-G188 WeakPolarHBondContact CG2-O 3.16Å; V186-G188 PolarHBondContact O-N 2.93Å; V186-P190 HydrophobicContact CG2-CB 4.35Å; V186-P190 HydrophobicContact CG2-CG 4Å; V186-F209 HydrophobicContact CB-CD2 4.34Å; V186-F209 HydrophobicContact CB-CE2 3.87Å; V186-F209 HydrophobicContact CB-CZ 4.26Å; V186-F209 HydrophobicContact CG1-CD1 4.41Å; V186-F209 HydrophobicContact CG1-CD2 4Å; V186-F209 HydrophobicContact CG1-CE1 4.14Å; V186-F209 HydrophobicContact CG1-CE2 3.71Å; V186-F209 HydrophobicContact CG1-CG 4.34Å; V186-F209 HydrophobicContact CG1-CZ 3.79Å; V186-I219 HydrophobicContact CG1-CD1 4.02Å
187P92.4Very high96.1Very high45 Ų4534.8 Ų34.829%0.29219%0.19SC..SBendtrans-72.5-3.1-168.230.3-41000115.3K215P187-K215 HydrophobicContact CB-CD 3.57Å; P187-K215 HydrophobicContact CG-CB 4.32Å; P187-K215 HydrophobicContact CG-CD 3.4Å; P187-K215 VanDerWaalsContact CG-CD 3.4Å; P187-K215 PolarHBondContact O-NZ 3Å; P187-K215 VanDerWaalsContact O-NZ 3.08Å
188G94.1Very high95.9Very high0 Ų036.6 Ų36.60%021%0.209CC..SBendtrans-165.4165.9-179.200000110.6V186 P190 T211V186-G188 WeakPolarHBondContact CG2-O 3.16Å; V186-G188 PolarHBondContact O-N 2.93Å; G188-P190 VanDerWaalsContact O-CD 3.25Å; G188-P190 WeakPolarHBondContact O-CD 3.3Å; G188-P190 VanDerWaalsContact O-N 3.15Å; G188-T211 WeakPolarHBondContact O-CG2 3.19Å
189P96.6Very high95.7Very high6 Ų637.8 Ų37.84%0.03921%0.211CC..  trans-60.3116.3-178.8-2433.3000111.6R170 T191 T211 S212R170-P189 HydrophobicContact CG-CG 4.12Å; P189-T191 PolarHBondContact O-N 3.5Å; P189-T211 CarbonylContact O-C 3.49Å; P189-T211 VanDerWaalsContact O-CA 3.23Å; P189-T211 WeakPolarHBondContact O-CA 3.07Å; P189-T211 WeakPolarHBondContact O-CB 3.49Å; P189-S212 WeakPolarHBondContact CD-OG 3.38Å; P189-S212 PolarHBondContact O-N 2.57Å
190P98.1Very high95.6Very high0 Ų031.9 Ų31.90%018%0.18CC..EExtended strand (participates in β ladder)trans-69.5129.1179.728.4-34.5000110.5N148 A166 C167 L172 V186 G188 G210N148-P190 WeakPolarHBondContact CB-O 3.49Å; N148-P190 PolarHBondContact ND2-O 3.3Å; A166-P190 HydrophobicContact CB-CB 3.8Å; A166-P190 HydrophobicContact CB-CG 3.78Å; C167-P190 VanDerWaalsContact O-CD 3.23Å; C167-P190 WeakPolarHBondContact O-CD 3.25Å; C167-P190 WeakPolarHBondContact O-CG 3.43Å; L172-P190 HydrophobicContact CD2-CB 3.78Å; L172-P190 HydrophobicContact CD2-CG 3.7Å; V186-P190 HydrophobicContact CG2-CB 4.35Å; V186-P190 HydrophobicContact CG2-CG 4Å; G188-P190 VanDerWaalsContact O-CD 3.25Å; G188-P190 WeakPolarHBondContact O-CD 3.3Å; G188-P190 VanDerWaalsContact O-N 3.15Å; P190-G210 CarbonylContact C-O 3.59Å; P190-G210 WeakPolarHBondContact CA-O 3.2Å
191T97.9Very high95.4Very high22 Ų2229.4 Ų29.414%0.13517%0.165CC..EExtended strand (participates in β ladder)trans-113.3-22.8-175.242.90000113.3Q18 P189 G210 I241Q18-T191 PolarHBondContact NE2-O 3.43Å; P189-T191 PolarHBondContact O-N 3.5Å; T191-G210 PolarHBondContact N-O 3.1Å; T191-G210 PolarHBondContact OG1-O 3.01Å; T191-I241 WeakPolarHBondContact CB-O 3.35Å; T191-I241 PolarHBondContact OG1-O 2.92Å
192V98.4Very high95.1Very high0 Ų033 Ų330%019%0.186CC..EExtended strand (participates in β ladder)trans-147.4140.317958.10000110.9K19 F209 G210 I241 I244K19-V192 HydrophobicContact CD-CG2 3.82Å; V192-F209 WeakPolarHBondContact O-CA 3.39Å; V192-G210 PolarHBondContact N-O 3.32Å; V192-G210 PolarHBondContact O-N 2.88Å; V192-I241 HydrophobicContact CG1-CB 4.34Å; V192-I241 HydrophobicContact CG1-CG2 3.74Å; V192-I244 HydrophobicContact CG1-CD1 3.7Å; V192-I244 HydrophobicContact CG1-CG1 3.96Å
193L98.4Very high94.8Very high1 Ų133.4 Ų33.41%0.00519%0.193CC..EExtended strand (participates in β ladder)trans-118.1145.4172.1-59.7-179000110.4K19 D149 I151 V164 A166 L172 L207 L208 F209K19-L193 PolarHBondContact NZ-O 2.83Å; D149-L193 HydrophobicContact CB-CG 4.31Å; D149-L193 PolarHBondContact OD2-N 2.9Å; I151-L193 HydrophobicContact CB-CB 4.18Å; I151-L193 HydrophobicContact CB-CD1 4.47Å; I151-L193 HydrophobicContact CD1-CB 4.44Å; I151-L193 HydrophobicContact CG2-CB 3.89Å; I151-L193 HydrophobicContact CG2-CD1 3.77Å; I151-L193 HydrophobicContact CG2-CG 4.49Å; V164-L193 HydrophobicContact CG1-CD1 4.33Å; A166-L193 HydrophobicContact CB-CD1 3.8Å; A166-L193 HydrophobicContact CB-CD2 4.13Å; A166-L193 HydrophobicContact CB-CG 3.86Å; L172-L193 HydrophobicContact CD2-CD2 3.92Å; L193-L207 HydrophobicContact CB-CD1 4.33Å; L193-L207 HydrophobicContact CD1-CD2 4.5Å; L193-L207 HydrophobicContact CD2-CD2 4.15Å; L193-L208 WeakPolarHBondContact CA-O 3.28Å; L193-F209 HydrophobicContact CD2-CB 3.66Å
194A97.8Very high94.6Very high14 Ų1428.6 Ų28.612%0.11617%0.171CC..EExtended strand (participates in β ladder)trans-147.1145.3173.400000110.8L207 L208 I244A194-L207 WeakPolarHBondContact O-CD1 3.3Å; A194-L208 HydrophobicContact CB-CB 4.43Å; A194-L208 PolarHBondContact N-O 3.03Å; A194-L208 WeakPolarHBondContact O-CB 3.36Å; A194-L208 PolarHBondContact O-N 3.33Å; A194-I244 HydrophobicContact CB-CB 4.15Å; A194-I244 HydrophobicContact CB-CG2 4.09Å
195L96.9Very high94.5Very high24 Ų2430 Ų3013%0.12618%0.177CC..EExtended strand (participates in β ladder)trans-72.9133.1170.5-66.4177.2000109.2I151 L153 N197 G198I151-L195 HydrophobicContact CD1-CD2 4.2Å; I151-L195 HydrophobicContact CD1-CG 3.83Å; I151-L195 HydrophobicContact CG1-CG 4.37Å; L153-L195 HydrophobicContact CD2-CD2 4.03Å; L195-N197 PolarHBondContact O-N 2.85Å; L195-G198 PolarHBondContact O-N 3.37Å
196H94.5Very high94.5Very high25 Ų2525.5 Ų25.512%0.11616%0.156CC..G310 helixtrans-58.6132.5174.2-175.657.9000110.1G198 N199 G200 G201 D206 L208 L218 F271H196-G198 PolarHBondContact O-N 3.28Å; H196-N199 PolarHBondContact O-N 3.25Å; H196-N199 PolarHBondContact O-OD1 2.95Å; H196-G200 PolarHBondContact O-N 2.84Å; H196-G201 PolarHBondContact O-N 2.82Å; H196-D206 HydrophobicContact CB-CB 3.74Å; H196-D206 PolarHBondContact N-O 3.16Å; H196-L208 HydrophobicContact CB-CD1 4.27Å; H196-L208 HydrophobicContact CB-CG 4.26Å; H196-L218 HydrophobicContact CB-CD1 3.88Å; H196-F271 AromaticContact CE1-CZ 3.83Å
197N91.9Very high94.6Very high35 Ų3525.2 Ų25.219%0.18716%0.155CC..G310 helixtrans58.210-173.9-65.1-24.2000115.7L195 N199 K255L195-N197 PolarHBondContact O-N 2.85Å; N197-N199 WeakPolarHBondContact CB-OD1 3.46Å; N197-N199 PolarHBondContact O-N 3.38Å; N197-K255 HydrophobicContact CB-CD 4.08Å; N197-K255 PolarHBondContact O-NZ 2.72Å
198G90.3Very high94.9Very high55 Ų5523 Ų2357%0.56714%0.141SC*.G310 helixtrans76.2-0.3-17400000114.7L195 H196L195-G198 PolarHBondContact O-N 3.37Å; H196-G198 PolarHBondContact O-N 3.28Å
199N91.3Very high95.1Very high69 Ų6923.1 Ų23.137%0.36914%0.141SC..THydrogen-bonded Turntrans-135.312-175.469.7-6.5000113.7P154 R157 H196 N197 G201P154-N199 WeakPolarHBondContact CG-O 3.08Å; R157-N199 WeakPolarHBondContact CD-O 3.34Å; R157-N199 PolarHBondContact NH1-ND2 2.95Å; R157-N199 PolarHBondContact NH1-O 3.41Å; H196-N199 PolarHBondContact O-N 3.25Å; H196-N199 PolarHBondContact O-OD1 2.95Å; N197-N199 WeakPolarHBondContact CB-OD1 3.46Å; N197-N199 PolarHBondContact O-N 3.38Å; N199-G201 PolarHBondContact OD1-N 3.24Å
200G92.8Very high95.2Very high0 Ų022.9 Ų22.90%014%0.139CC..THydrogen-bonded Turntrans79.325.1178.500000114.3H196 G204 E205 D206H196-G200 PolarHBondContact O-N 2.84Å; G200-G204 CarbonylContact O-C 3.58Å; G200-G204 WeakPolarHBondContact O-CA 3.19Å; G200-G204 PolarHBondContact O-N 3.3Å; G200-E205 PolarHBondContact O-N 3.43Å; G200-E205 VanDerWaalsContact O-N 3.08Å; G200-D206 VanDerWaalsContact O-CB 3.32Å; G200-D206 WeakPolarHBondContact O-CB 3.37Å; G200-D206 PolarHBondContact O-N 3.1Å
201G92.3Very high95.2Very high1 Ų122.9 Ų22.91%0.0114%0.139CC..THydrogen-bonded Turntrans67.1-166.1-178.100000113R157 H196 N199 S203 G204R157-G201 PolarHBondContact NH1-O 3.3Å; R157-G201 PolarHBondContact NH2-O 3.03Å; H196-G201 PolarHBondContact O-N 2.82Å; N199-G201 PolarHBondContact OD1-N 3.24Å; G201-S203 VanDerWaalsContact C-N 3.3Å; G201-S203 PolarHBondContact O-N 2.91Å; G201-G204 PolarHBondContact O-N 2.92Å
202D89.7Confident95Very high153 Ų15322.8 Ų22.882%0.81814%0.14SC*.THydrogen-bonded Turntrans-70.1-25.8-175.4-65.5-30.7000113.9R157R157-D202 PolarHBondContact NH2-O 3.22Å
203S89.8Confident94.7Very high41 Ų4125.3 Ų25.329%0.28715%0.153SC..THydrogen-bonded Turntrans-84.3-21.2176580000113.1L158 G201 E205L158-S203 WeakPolarHBondContact CD2-O 3.5Å; G201-S203 VanDerWaalsContact C-N 3.3Å; G201-S203 PolarHBondContact O-N 2.91Å; S203-E205 PolarHBondContact O-N 3.49Å; S203-E205 PolarHBondContact OG-N 3.33Å; S203-E205 VanDerWaalsContact OG-N 3.13Å
204G93.6Very high94.6Very high0 Ų025.3 Ų25.30%015%0.153CC..SBendtrans76.71.1-165.800000113.6P154 G200 G201P154-G204 WeakPolarHBondContact CD-O 3.47Å; P154-G204 WeakPolarHBondContact CG-O 3.27Å; G200-G204 CarbonylContact O-C 3.58Å; G200-G204 WeakPolarHBondContact O-CA 3.19Å; G200-G204 PolarHBondContact O-N 3.3Å; G201-G204 PolarHBondContact O-N 2.92Å
205E95.4Very high94.5Very high31 Ų3126.8 Ų26.815%0.14516%0.157CC..  trans-109.52.4-174.7-62.6-170.5143.600113.4L158 R160 G200 S203 Q220 I221L158-E205 HydrophobicContact CD1-CG 3.83Å; L158-E205 HydrophobicContact CD2-CG 3.53Å; L158-E205 HydrophobicContact CG-CG 4.34Å; R160-E205 IonicContact NH2-OE1 2.74Å; R160-E205 PolarHBondContact NH2-OE1 2.93Å; G200-E205 PolarHBondContact O-N 3.43Å; G200-E205 VanDerWaalsContact O-N 3.08Å; S203-E205 PolarHBondContact O-N 3.49Å; S203-E205 PolarHBondContact OG-N 3.33Å; S203-E205 VanDerWaalsContact OG-N 3.13Å; E205-Q220 HydrophobicContact CB-CG 3.85Å; E205-Q220 WeakPolarHBondContact O-CA 3.39Å; E205-Q220 PolarHBondContact OE2-NE2 2.86Å; E205-I221 WeakPolarHBondContact CB-O 3.46Å; E205-I221 PolarHBondContact O-N 3.4Å
206D96.8Very high94.5Very high7 Ų725.7 Ų25.74%0.03715%0.151CC..EExtended strand (participates in β ladder)trans-87.8117.2-173.6-68.6-24.9000112.1H196 G200 L218 Q220 K229H196-D206 HydrophobicContact CB-CB 3.74Å; H196-D206 PolarHBondContact N-O 3.16Å; G200-D206 VanDerWaalsContact O-CB 3.32Å; G200-D206 WeakPolarHBondContact O-CB 3.37Å; G200-D206 PolarHBondContact O-N 3.1Å; D206-L218 HydrophobicContact CB-CD1 4.16Å; D206-Q220 WeakPolarHBondContact OD1-CB 3.2Å; D206-Q220 WeakPolarHBondContact OD1-CG 3.29Å; D206-K229 WeakPolarHBondContact OD1-CE 3.38Å; D206-K229 IonicContact OD1-NZ 3.53Å; D206-K229 PolarHBondContact OD1-NZ 3.41Å; D206-K229 IonicContact OD2-NZ 3.84Å; D206-K229 PolarHBondContact OD2-NZ 2.8Å
207L98.1Very high94.6Very high0 Ų024.5 Ų24.50%015%0.146CC..EExtended strand (participates in β ladder)trans-113.3126.8-179.1-176.471.1000111.3I151 V164 L172 L193 A194 I219 I221I151-L207 HydrophobicContact CD1-CD1 4.28Å; I151-L207 HydrophobicContact CG2-CD1 3.61Å; V164-L207 HydrophobicContact CB-CD2 4.25Å; V164-L207 HydrophobicContact CG1-CD2 3.8Å; V164-L207 HydrophobicContact CG2-CD2 4.39Å; L172-L207 HydrophobicContact CD1-CD2 4.3Å; L193-L207 HydrophobicContact CB-CD1 4.33Å; L193-L207 HydrophobicContact CD1-CD2 4.5Å; L193-L207 HydrophobicContact CD2-CD2 4.15Å; A194-L207 WeakPolarHBondContact O-CD1 3.3Å; L207-I219 PolarHBondContact N-O 2.88Å; L207-I219 PolarHBondContact O-N 2.85Å; L207-I221 HydrophobicContact CB-CD1 3.87Å; L207-I221 HydrophobicContact CB-CG1 4.33Å; L207-I221 HydrophobicContact CD2-CD1 3.52Å; L207-I221 HydrophobicContact CG-CD1 4.3Å
208L98.1Very high94.9Very high0 Ų023 Ų230%014%0.138CC..EExtended strand (participates in β ladder)trans-90.2136.3167.7-68.7162.9000109.8L193 A194 H196 G217 L218 W230 I244 L257L193-L208 WeakPolarHBondContact CA-O 3.28Å; A194-L208 HydrophobicContact CB-CB 4.43Å; A194-L208 PolarHBondContact N-O 3.03Å; A194-L208 WeakPolarHBondContact O-CB 3.36Å; A194-L208 PolarHBondContact O-N 3.33Å; H196-L208 HydrophobicContact CB-CD1 4.27Å; H196-L208 HydrophobicContact CB-CG 4.26Å; L208-G217 WeakPolarHBondContact CA-O 3.39Å; L208-L218 HydrophobicContact CD2-CB 4.08Å; L208-L218 HydrophobicContact CD2-CD1 3.59Å; L208-L218 HydrophobicContact CD2-CG 4.42Å; L208-L218 HydrophobicContact CG-CD1 3.81Å; L208-W230 HydrophobicContact CD2-CH2 3.53Å; L208-W230 HydrophobicContact CD2-CZ2 3.79Å; L208-I244 HydrophobicContact CD1-CG2 4.39Å; L208-L257 HydrophobicContact CD1-CD1 3.63Å; L208-L257 HydrophobicContact CD2-CD2 4.3Å
209F98.5Very high95.2Very high2 Ų220.5 Ų20.51%0.00911%0.112CC..EExtended strand (participates in β ladder)trans-127.9142.5171.874.3-84.9000110.7L172 V186 V192 L193 T211 L216 G217 I219L172-F209 HydrophobicContact CD1-CB 4.33Å; L172-F209 HydrophobicContact CD1-CG 4.44Å; V186-F209 HydrophobicContact CB-CD2 4.34Å; V186-F209 HydrophobicContact CB-CE2 3.87Å; V186-F209 HydrophobicContact CB-CZ 4.26Å; V186-F209 HydrophobicContact CG1-CD1 4.41Å; V186-F209 HydrophobicContact CG1-CD2 4Å; V186-F209 HydrophobicContact CG1-CE1 4.14Å; V186-F209 HydrophobicContact CG1-CE2 3.71Å; V186-F209 HydrophobicContact CG1-CG 4.34Å; V186-F209 HydrophobicContact CG1-CZ 3.79Å; V192-F209 WeakPolarHBondContact O-CA 3.39Å; L193-F209 HydrophobicContact CD2-CB 3.66Å; F209-T211 HydrophobicContact CD2-CG2 3.82Å; F209-T211 HydrophobicContact CE2-CG2 3.73Å; F209-L216 WeakPolarHBondContact O-CA 3.4Å; F209-L216 WeakPolarHBondContact O-CD1 3.31Å; F209-G217 VanDerWaalsContact CD1-O 3.26Å; F209-G217 WeakPolarHBondContact CD1-O 3.35Å; F209-G217 PolarHBondContact N-O 2.88Å; F209-G217 PolarHBondContact O-N 2.81Å; F209-I219 HydrophobicContact CD1-CD1 3.58Å; F209-I219 HydrophobicContact CD1-CG1 4.04Å; F209-I219 HydrophobicContact CE1-CD1 3.33Å; F209-I219 HydrophobicContact CE1-CG1 3.72Å; F209-I219 HydrophobicContact CZ-CD1 4.23Å
210G98.3Very high95.5Very high0 Ų019 Ų190%010%0.102CC..EExtended strand (participates in β ladder)trans-118.7144.2168.900000110.9P190 T191 V192 K215P190-G210 CarbonylContact C-O 3.59Å; P190-G210 WeakPolarHBondContact CA-O 3.2Å; T191-G210 PolarHBondContact N-O 3.1Å; T191-G210 PolarHBondContact OG1-O 3.01Å; V192-G210 PolarHBondContact N-O 3.32Å; V192-G210 PolarHBondContact O-N 2.88Å; G210-K215 WeakPolarHBondContact CA-O 3.39Å
211T97.8Very high95.7Very high0 Ų019 Ų190%010%0.102CC..EExtended strand (participates in β ladder)trans-110.7160.7-176.365.10000113.4G188 P189 F209 D213 G214 K215 I241G188-T211 WeakPolarHBondContact O-CG2 3.19Å; P189-T211 CarbonylContact O-C 3.49Å; P189-T211 VanDerWaalsContact O-CA 3.23Å; P189-T211 WeakPolarHBondContact O-CA 3.07Å; P189-T211 WeakPolarHBondContact O-CB 3.49Å; F209-T211 HydrophobicContact CD2-CG2 3.82Å; F209-T211 HydrophobicContact CE2-CG2 3.73Å; T211-D213 WeakPolarHBondContact CB-OD1 3.44Å; T211-D213 PolarHBondContact O-N 3.18Å; T211-D213 PolarHBondContact OG1-OD1 3.39Å; T211-G214 PolarHBondContact O-N 3.43Å; T211-K215 HydrophobicContact CG2-CB 4.49Å; T211-K215 PolarHBondContact N-O 2.97Å; T211-K215 WeakPolarHBondContact OG1-CA 3.45Å; T211-K215 WeakPolarHBondContact OG1-CB 3.4Å; T211-K215 PolarHBondContact OG1-N 3.17Å; T211-K215 PolarHBondContact OG1-O 3.31Å; T211-I241 PolarHBondContact O-N 2.65Å
212S95.1Very high95.8Very high21 Ų2120 Ų2015%0.14711%0.109CC..THydrogen-bonded Turntrans-66.8-18.7179.964.90000114.5P189 G240 K384P189-S212 WeakPolarHBondContact CD-OG 3.38Å; P189-S212 PolarHBondContact O-N 2.57Å; S212-G240 WeakPolarHBondContact O-CA 3.35Å; S212-K384 PolarHBondContact O-NZ 3.44Å
213D92.2Very high95.7Very high52 Ų5216.9 Ų16.928%0.27810%0.095SC..THydrogen-bonded Turntrans-99.910.417566.9-21.5000112.6T211 K215 N234T211-D213 WeakPolarHBondContact CB-OD1 3.44Å; T211-D213 PolarHBondContact O-N 3.18Å; T211-D213 PolarHBondContact OG1-OD1 3.39Å; D213-K215 IonicContact OD2-NZ 3.6Å; D213-K215 PolarHBondContact OD2-NZ 3.43Å; D213-N234 PolarHBondContact O-ND2 2.96Å
214G94.8Very high95.6Very high1 Ų118.9 Ų18.91%0.0111%0.109CC..SBendtrans90.514.3164.800000115.6T211 G239 R261T211-G214 PolarHBondContact O-N 3.43Å; G214-G239 WeakPolarHBondContact CA-O 3.49Å; G214-R261 PolarHBondContact O-NH1 3.36Å
215K96.3Very high95.6Very high45 Ų4525.1 Ų25.120%0.19614%0.136CC..  trans-89.4148.6175.3-56.6175.1-178.7120.40110.5P187 G210 T211 D213 I232 I241P187-K215 HydrophobicContact CB-CD 3.57Å; P187-K215 HydrophobicContact CG-CB 4.32Å; P187-K215 HydrophobicContact CG-CD 3.4Å; P187-K215 VanDerWaalsContact CG-CD 3.4Å; P187-K215 PolarHBondContact O-NZ 3Å; P187-K215 VanDerWaalsContact O-NZ 3.08Å; G210-K215 WeakPolarHBondContact CA-O 3.39Å; T211-K215 HydrophobicContact CG2-CB 4.49Å; T211-K215 PolarHBondContact N-O 2.97Å; T211-K215 WeakPolarHBondContact OG1-CA 3.45Å; T211-K215 WeakPolarHBondContact OG1-CB 3.4Å; T211-K215 PolarHBondContact OG1-N 3.17Å; T211-K215 PolarHBondContact OG1-O 3.31Å; D213-K215 IonicContact OD2-NZ 3.6Å; D213-K215 PolarHBondContact OD2-NZ 3.43Å; K215-I232 WeakPolarHBondContact CA-O 3.5Å; K215-I241 VanDerWaalsContact O-CD1 3.24Å; K215-I241 WeakPolarHBondContact O-CD1 3.42Å
216L97.1Very high95.7Very high1 Ų125.4 Ų25.41%0.00514%0.141CC..EExtended strand (participates in β ladder)trans-127.6141.4178.9-175.271.1000108.3F209 W230 E231 I232 I241 I244 L257 V259F209-L216 WeakPolarHBondContact O-CA 3.4Å; F209-L216 WeakPolarHBondContact O-CD1 3.31Å; L216-W230 HydrophobicContact CD2-CH2 4.37Å; L216-W230 HydrophobicContact CD2-CZ3 4.3Å; L216-W230 HydrophobicContact CG-CH2 4.43Å; L216-W230 HydrophobicContact CG-CZ3 4.15Å; L216-E231 CarbonylContact O-C 3.56Å; L216-E231 WeakPolarHBondContact O-CA 3.29Å; L216-I232 HydrophobicContact CB-CB 4.21Å; L216-I232 HydrophobicContact CB-CD1 4.48Å; L216-I232 HydrophobicContact CD2-CD1 3.71Å; L216-I232 PolarHBondContact N-O 2.95Å; L216-I232 VanDerWaalsContact N-O 3.14Å; L216-I232 PolarHBondContact O-N 3.43Å; L216-I241 HydrophobicContact CB-CD1 3.76Å; L216-I241 HydrophobicContact CD1-CD1 3.95Å; L216-I241 HydrophobicContact CG-CD1 4.41Å; L216-I244 HydrophobicContact CD1-CD1 3.43Å; L216-I244 VanDerWaalsContact CD1-CD1 3.43Å; L216-I244 HydrophobicContact CD1-CG1 4.18Å; L216-L257 HydrophobicContact CD2-CD2 3.33Å; L216-L257 HydrophobicContact CD2-CG 4.26Å; L216-L257 HydrophobicContact CG-CD2 4.31Å; L216-V259 HydrophobicContact CD2-CG2 3.95Å
217G97.3Very high95.7Very high0 Ų028.6 Ų28.60%016%0.157CC..EExtended strand (participates in β ladder)trans-152.6161.3175.200000113.4L208 F209 W230L208-G217 WeakPolarHBondContact CA-O 3.39Å; F209-G217 VanDerWaalsContact CD1-O 3.26Å; F209-G217 WeakPolarHBondContact CD1-O 3.35Å; F209-G217 PolarHBondContact N-O 2.88Å; F209-G217 PolarHBondContact O-N 2.81Å; G217-W230 WeakPolarHBondContact CA-O 3.16Å
218L97.4Very high95.6Very high5 Ų533.6 Ų33.63%0.02618%0.18CC..EExtended strand (participates in β ladder)trans-115.6120.6176.2-176.169.5000109.7H196 D206 L208 K229 W230H196-L218 HydrophobicContact CB-CD1 3.88Å; D206-L218 HydrophobicContact CB-CD1 4.16Å; L208-L218 HydrophobicContact CD2-CB 4.08Å; L208-L218 HydrophobicContact CD2-CD1 3.59Å; L208-L218 HydrophobicContact CD2-CG 4.42Å; L208-L218 HydrophobicContact CG-CD1 3.81Å; L218-K229 HydrophobicContact CB-CB 4.24Å; L218-K229 HydrophobicContact CD2-CB 3.96Å; L218-K229 HydrophobicContact CD2-CD 3.57Å; L218-K229 HydrophobicContact CD2-CG 4.36Å; L218-K229 HydrophobicContact CG-CB 4.14Å; L218-K229 HydrophobicContact CG-CD 4.05Å; L218-K229 PolarHBondContact O-N 2.84Å; L218-W230 HydrophobicContact CB-CD2 3.75Å; L218-W230 HydrophobicContact CB-CE3 4.24Å; L218-W230 HydrophobicContact CB-CG 4.26Å; L218-W230 HydrophobicContact CB-CH2 4.08Å; L218-W230 HydrophobicContact CB-CZ2 3.58Å; L218-W230 HydrophobicContact CB-CZ3 4.38Å; L218-W230 HydrophobicContact CD2-CZ2 4.09Å; L218-W230 VanDerWaalsContact CD2-NE1 3.33Å; L218-W230 HydrophobicContact CG-CZ2 4.34Å; L218-W230 PolarHBondContact N-O 3.09Å
219I97.6Very high95.4Very high1 Ų138.1 Ų38.11%0.00520%0.2CC..EExtended strand (participates in β ladder)trans-123.4127.6178.8-60.7166.1000108.5L172 I184 V186 L207 F209 I221 P226L172-I219 HydrophobicContact CD1-CD1 4.01Å; I184-I219 HydrophobicContact CD1-CG2 4.19Å; I184-I219 HydrophobicContact CG2-CD1 3.96Å; I184-I219 HydrophobicContact CG2-CG2 4.47Å; V186-I219 HydrophobicContact CG1-CD1 4.02Å; L207-I219 PolarHBondContact N-O 2.88Å; L207-I219 PolarHBondContact O-N 2.85Å; F209-I219 HydrophobicContact CD1-CD1 3.58Å; F209-I219 HydrophobicContact CD1-CG1 4.04Å; F209-I219 HydrophobicContact CE1-CD1 3.33Å; F209-I219 HydrophobicContact CE1-CG1 3.72Å; F209-I219 HydrophobicContact CZ-CD1 4.23Å; I219-I221 HydrophobicContact CG2-CG1 4.43Å; I219-P226 HydrophobicContact CG2-CB 3.75Å
220Q97.3Very high95.3Very high37 Ų3739.8 Ų39.817%0.17321%0.206CC..EExtended strand (participates in β ladder)trans-86.8124.8168.7-174.7-179.5-8.800109.7E205 D206 T222 P226 I227E205-Q220 HydrophobicContact CB-CG 3.85Å; E205-Q220 WeakPolarHBondContact O-CA 3.39Å; E205-Q220 PolarHBondContact OE2-NE2 2.86Å; D206-Q220 WeakPolarHBondContact OD1-CB 3.2Å; D206-Q220 WeakPolarHBondContact OD1-CG 3.29Å; Q220-T222 HydrophobicContact CG-CG2 4.41Å; Q220-P226 WeakPolarHBondContact O-CA 3.16Å; Q220-I227 HydrophobicContact CB-CB 4.23Å; Q220-I227 PolarHBondContact N-O 3.47Å; Q220-I227 PolarHBondContact O-N 3.35Å
221I96.1Very high95.2Very high1 Ų143.6 Ų43.61%0.00522%0.224CC..EExtended strand (participates in β ladder)trans-9995.9-176.2-60.7-178000109L153 V164 V174 Y182 I184 E205 L207 I219L153-I221 HydrophobicContact CD1-CB 4.03Å; L153-I221 HydrophobicContact CD1-CG2 4Å; V164-I221 HydrophobicContact CB-CD1 4.41Å; V164-I221 HydrophobicContact CG1-CD1 4.11Å; V164-I221 HydrophobicContact CG2-CD1 3.5Å; V174-I221 HydrophobicContact CG1-CG2 3.78Å; V174-I221 HydrophobicContact CG2-CD1 4.36Å; V174-I221 HydrophobicContact CG2-CG2 3.92Å; Y182-I221 VanDerWaalsContact OH-CG2 3.25Å; Y182-I221 WeakPolarHBondContact OH-CG2 3.3Å; I184-I221 HydrophobicContact CD1-CD1 4.42Å; I184-I221 HydrophobicContact CD1-CG1 4.22Å; E205-I221 WeakPolarHBondContact CB-O 3.46Å; E205-I221 PolarHBondContact O-N 3.4Å; L207-I221 HydrophobicContact CB-CD1 3.87Å; L207-I221 HydrophobicContact CB-CG1 4.33Å; L207-I221 HydrophobicContact CD2-CD1 3.52Å; L207-I221 HydrophobicContact CG-CD1 4.3Å; I219-I221 HydrophobicContact CG2-CG1 4.43Å
222T93.8Very high95Very high23 Ų2344.9 Ų44.914%0.14123%0.23CC..  trans-84.1-175.9178.778.90000111.7Y182 Q220 S224 K225 I227Y182-T222 PolarHBondContact OH-N 3.1Å; Y182-T222 PolarHBondContact OH-O 2.75Å; Q220-T222 HydrophobicContact CG-CG2 4.41Å; T222-S224 VanDerWaalsContact C-N 3.28Å; T222-S224 PolarHBondContact O-N 2.78Å; T222-S224 PolarHBondContact OG1-N 3.04Å; T222-K225 WeakPolarHBondContact CB-O 3.16Å; T222-K225 PolarHBondContact N-O 2.89Å; T222-K225 PolarHBondContact OG1-N 2.91Å; T222-K225 PolarHBondContact OG1-O 3.38Å; T222-I227 HydrophobicContact CG2-CD1 3.77Å; T222-I227 HydrophobicContact CG2-CG1 4.11Å
223T88.5Confident94.9Very high86 Ų8652.6 Ų52.653%0.52826%0.256SS..SBendtrans-62.7-28.5175.648.10000114.7M181M181-T223 WeakPolarHBondContact CE-O 3.36Å
224S88.1Confident94.7Very high84 Ų8451.4 Ų51.459%0.58725%0.25SS*.SBendtrans-135.1-19.5-168.763.10000114.9T222T222-S224 VanDerWaalsContact C-N 3.28Å; T222-S224 PolarHBondContact O-N 2.78Å; T222-S224 PolarHBondContact OG1-N 3.04Å
225K93.4Very high94.3Very high131 Ų13159.4 Ų59.457%0.5729%0.287SS*.  trans-152.5150.7-17961.6175.5-179.2175.80112.5T222T222-K225 WeakPolarHBondContact CB-O 3.16Å; T222-K225 PolarHBondContact N-O 2.89Å; T222-K225 PolarHBondContact OG1-N 2.91Å; T222-K225 PolarHBondContact OG1-O 3.38Å
226P96.8Very high93.7Very high37 Ų3763.7 Ų63.724%0.2431%0.306CS..EExtended strand (participates in β ladder)trans-72.6151.9169.131.7-33.8000111.2Y182 I184 I219 Q220Y182-P226 HydrophobicContact CE2-CB 4.4Å; Y182-P226 HydrophobicContact CE2-CG 4.38Å; I184-P226 HydrophobicContact CB-CB 4.41Å; I184-P226 HydrophobicContact CB-CG 4.4Å; I184-P226 HydrophobicContact CD1-CB 3.87Å; I184-P226 HydrophobicContact CG1-CB 3.82Å; I184-P226 HydrophobicContact CG1-CG 3.96Å; I184-P226 HydrophobicContact CG2-CB 3.77Å; I184-P226 HydrophobicContact CG2-CG 3.87Å; I219-P226 HydrophobicContact CG2-CB 3.75Å; Q220-P226 WeakPolarHBondContact O-CA 3.16Å
227I96.9Very high93.2Very high73 Ų7369.2 Ų69.237%0.37433%0.33SS..EExtended strand (participates in β ladder)trans-122.9111165.3-55.8172.6000107.2Q220 T222 K229Q220-I227 HydrophobicContact CB-CB 4.23Å; Q220-I227 PolarHBondContact N-O 3.47Å; Q220-I227 PolarHBondContact O-N 3.35Å; T222-I227 HydrophobicContact CG2-CD1 3.77Å; T222-I227 HydrophobicContact CG2-CG1 4.11Å; I227-K229 PolarHBondContact O-N 2.91Å
228H95.8Very high92.7Very high105 Ų10570.6 Ų70.649%0.48634%0.335SS..EExtended strand (participates in β ladder)trans-75.2120.1175.3-66.1-108.3000108.5
229K95.3Very high92.4Very high95 Ų9570.9 Ų70.941%0.41334%0.339SS..EExtended strand (participates in β ladder)trans-88.2-54.6179.6-73.7-176.5166.9176.90110.9D206 L218 I227D206-K229 WeakPolarHBondContact OD1-CE 3.38Å; D206-K229 IonicContact OD1-NZ 3.53Å; D206-K229 PolarHBondContact OD1-NZ 3.41Å; D206-K229 IonicContact OD2-NZ 3.84Å; D206-K229 PolarHBondContact OD2-NZ 2.8Å; L218-K229 HydrophobicContact CB-CB 4.24Å; L218-K229 HydrophobicContact CD2-CB 3.96Å; L218-K229 HydrophobicContact CD2-CD 3.57Å; L218-K229 HydrophobicContact CD2-CG 4.36Å; L218-K229 HydrophobicContact CG-CB 4.14Å; L218-K229 HydrophobicContact CG-CD 4.05Å; L218-K229 PolarHBondContact O-N 2.84Å; I227-K229 PolarHBondContact O-N 2.91Å
230W95.6Very high92.3Very high38 Ų3870.9 Ų70.914%0.14434%0.339CS..EExtended strand (participates in β ladder)trans-157.1163.3177.251.6-108000111.2L208 L216 G217 L218 I232 L257 F271 P277L208-W230 HydrophobicContact CD2-CH2 3.53Å; L208-W230 HydrophobicContact CD2-CZ2 3.79Å; L216-W230 HydrophobicContact CD2-CH2 4.37Å; L216-W230 HydrophobicContact CD2-CZ3 4.3Å; L216-W230 HydrophobicContact CG-CH2 4.43Å; L216-W230 HydrophobicContact CG-CZ3 4.15Å; G217-W230 WeakPolarHBondContact CA-O 3.16Å; L218-W230 HydrophobicContact CB-CD2 3.75Å; L218-W230 HydrophobicContact CB-CE3 4.24Å; L218-W230 HydrophobicContact CB-CG 4.26Å; L218-W230 HydrophobicContact CB-CH2 4.08Å; L218-W230 HydrophobicContact CB-CZ2 3.58Å; L218-W230 HydrophobicContact CB-CZ3 4.38Å; L218-W230 HydrophobicContact CD2-CZ2 4.09Å; L218-W230 VanDerWaalsContact CD2-NE1 3.33Å; L218-W230 HydrophobicContact CG-CZ2 4.34Å; L218-W230 PolarHBondContact N-O 3.09Å; W230-I232 HydrophobicContact CE3-CG1 4.06Å; W230-I232 HydrophobicContact CZ3-CD1 4.08Å; W230-I232 HydrophobicContact CZ3-CG1 3.86Å; W230-L257 HydrophobicContact CH2-CD2 3.82Å; W230-F271 AromaticContact CZ2-CE1 3.76Å; W230-F271 HydrophobicContact CZ2-CE1 3.76Å; W230-F271 HydrophobicContact CZ2-CZ 4.23Å; W230-P277 HydrophobicContact CD2-CG 3.95Å; W230-P277 HydrophobicContact CE3-CG 3.8Å; W230-P277 HydrophobicContact CH2-CG 4.28Å; W230-P277 HydrophobicContact CZ2-CG 4.39Å; W230-P277 HydrophobicContact CZ3-CG 3.99Å
231E95.8Very high92.3Very high79 Ų7969.1 Ų69.137%0.36933%0.331SS..EExtended strand (participates in β ladder)trans-139.8132.6175.7-176.6-176.1124.100109.6L216L216-E231 CarbonylContact O-C 3.56Å; L216-E231 WeakPolarHBondContact O-CA 3.29Å
232I95.1Very high92.4Very high27 Ų2770.7 Ų70.714%0.13834%0.339CS..EExtended strand (participates in β ladder)trans-97.3114.8169.3-49.1-179.7000108.1K215 L216 W230 Y269 P277K215-I232 WeakPolarHBondContact CA-O 3.5Å; L216-I232 HydrophobicContact CB-CB 4.21Å; L216-I232 HydrophobicContact CB-CD1 4.48Å; L216-I232 HydrophobicContact CD2-CD1 3.71Å; L216-I232 PolarHBondContact N-O 2.95Å; L216-I232 VanDerWaalsContact N-O 3.14Å; L216-I232 PolarHBondContact O-N 3.43Å; W230-I232 HydrophobicContact CE3-CG1 4.06Å; W230-I232 HydrophobicContact CZ3-CD1 4.08Å; W230-I232 HydrophobicContact CZ3-CG1 3.86Å; I232-Y269 HydrophobicContact CD1-CD1 3.78Å; I232-Y269 HydrophobicContact CD1-CE1 3.75Å; I232-Y269 HydrophobicContact CD1-CE2 4.5Å; I232-Y269 HydrophobicContact CD1-CG 4.2Å; I232-Y269 HydrophobicContact CG2-CE1 4.35Å; I232-P277 HydrophobicContact CD1-CB 3.65Å; I232-P277 HydrophobicContact CD1-CG 3.43Å; I232-P277 VanDerWaalsContact CD1-CG 3.43Å; I232-P277 HydrophobicContact CG1-CB 4.32Å; I232-P277 HydrophobicContact CG1-CG 3.53Å
233R91.3Very high92.7Very high183 Ų18369.7 Ų69.769%0.69133%0.333SS*.  trans-78.4155.4175.4-64.8-179.1179.1173.62.2111E235R233-E235 HydrophobicContact CB-CG 4.41Å; R233-E235 PolarHBondContact O-N 3.18Å
234N88.8Confident93.1Very high28 Ų2866.3 Ų66.315%0.1531%0.312CS..  trans-92.359.9-178.8-169.515.3000112.8D213 K236 K237 R238D213-N234 PolarHBondContact O-ND2 2.96Å; N234-K236 VanDerWaalsContact C-N 3.27Å; N234-K236 PolarHBondContact O-N 3.09Å; N234-K237 PolarHBondContact O-N 3.39Å; N234-K237 PolarHBondContact OD1-N 2.95Å; N234-R238 PolarHBondContact ND2-N 3.27Å; N234-R238 PolarHBondContact ND2-O 3.44Å; N234-R238 PolarHBondContact OD1-N 3.44Å
235E85.8Confident93.6Very high169 Ų16964.1 Ų64.179%0.7929%0.294SS*.THydrogen-bonded Turntrans-61.6-35.4-175.4-62.4-180172.400112.8R233 K237R233-E235 HydrophobicContact CB-CG 4.41Å; R233-E235 PolarHBondContact O-N 3.18Å; E235-K237 PolarHBondContact O-N 2.91Å
236K84.8Confident93.8Very high134 Ų13458.4 Ų58.458%0.58327%0.27SS*.THydrogen-bonded Turntrans-805.7178.1-66.2-178.4179.6177.90113.6N234 R238 D282N234-K236 VanDerWaalsContact C-N 3.27Å; N234-K236 PolarHBondContact O-N 3.09Å; K236-R238 HydrophobicContact CB-CG 3.97Å; K236-R238 PolarHBondContact O-N 3.3Å; K236-D282 IonicContact NZ-OD2 2.68Å
237K85.1Confident93.7Very high117 Ų11758.7 Ų58.751%0.50927%0.268SS..  trans49.843.3179.9-59.4-177.6176.9-178.40113N234 E235 D390N234-K237 PolarHBondContact O-N 3.39Å; N234-K237 PolarHBondContact OD1-N 2.95Å; E235-K237 PolarHBondContact O-N 2.91Å; K237-D390 WeakPolarHBondContact CE-OD2 3.38Å
238R87.4Confident93.6Very high30 Ų3057 Ų5711%0.11326%0.259CS..PPolyproline II helixtrans-74.6167.5177.4-63.1-178.1171.7177.8-6.1111.2N234 K236 E267 D282N234-R238 PolarHBondContact ND2-N 3.27Å; N234-R238 PolarHBondContact ND2-O 3.44Å; N234-R238 PolarHBondContact OD1-N 3.44Å; K236-R238 HydrophobicContact CB-CG 3.97Å; K236-R238 PolarHBondContact O-N 3.3Å; R238-E267 WeakPolarHBondContact CD-OE1 3.2Å; R238-E267 IonicContact CZ-OE1 3.35Å; R238-E267 IonicContact NE-OE1 3.79Å; R238-E267 VanDerWaalsContact NH1-CD 3.26Å; R238-E267 IonicContact NH1-OE1 3.99Å; R238-E267 PolarHBondContact NH1-OE1 2.92Å; R238-D282 IonicContact CZ-OD2 2.93Å; R238-D282 IonicContact NH1-OD2 3.48Å; R238-D282 IonicContact NH2-OD2 2.77Å; R238-D282 PolarHBondContact NH2-OD2 2.92Å
239G90.8Very high93.5Very high10 Ų1052.4 Ų52.410%0.10324%0.238CC..PPolyproline II helixtrans-58.3165.9178.100000115.1G214 R261 D262 D263G214-G239 WeakPolarHBondContact CA-O 3.49Å; G239-R261 WeakPolarHBondContact O-CD 3.32Å; G239-R261 PolarHBondContact O-NH1 3.16Å; G239-D262 VanDerWaalsContact C-OD1 3.31Å; G239-D262 WeakPolarHBondContact CA-OD1 3.45Å; G239-D263 PolarHBondContact N-OD1 2.73Å; G239-D263 PolarHBondContact N-OD2 2.81Å
240G95.8Very high93.3Very high2 Ų250.4 Ų50.42%0.02123%0.234CC..PPolyproline II helixtrans-63.1149.6172.300000111.9S212 R261 D262S212-G240 WeakPolarHBondContact O-CA 3.35Å; G240-R261 CarbonylContact O-C 3.53Å; G240-R261 VanDerWaalsContact O-CA 3.27Å; G240-R261 WeakPolarHBondContact O-CA 3.43Å; G240-D262 PolarHBondContact N-OD1 2.94Å; G240-D262 PolarHBondContact N-OD2 2.84Å; G240-D262 PolarHBondContact O-N 2.97Å
241I98.2Very high92.9Very high0 Ų050.7 Ų50.70%025%0.249CC..EExtended strand (participates in β ladder)trans-83123.5-177.3-53.8-172.8000109.8T191 V192 T211 K215 L216 I244 V259T191-I241 WeakPolarHBondContact CB-O 3.35Å; T191-I241 PolarHBondContact OG1-O 2.92Å; V192-I241 HydrophobicContact CG1-CB 4.34Å; V192-I241 HydrophobicContact CG1-CG2 3.74Å; T211-I241 PolarHBondContact O-N 2.65Å; K215-I241 VanDerWaalsContact O-CD1 3.24Å; K215-I241 WeakPolarHBondContact O-CD1 3.42Å; L216-I241 HydrophobicContact CB-CD1 3.76Å; L216-I241 HydrophobicContact CD1-CD1 3.95Å; L216-I241 HydrophobicContact CG-CD1 4.41Å; I241-I244 HydrophobicContact CG2-CD1 4.11Å; I241-I244 HydrophobicContact CG2-CG1 3.81Å; I241-V259 HydrophobicContact CD1-CG1 4.08Å; I241-V259 HydrophobicContact CG1-CG1 4.27Å; I241-V259 HydrophobicContact CG2-CG1 3.69Å
242L98.3Very high92.5Very high33 Ų3351.5 Ų51.517%0.17326%0.255CS..EExtended strand (participates in β ladder)trans-104.8-30.9-179.9-70-177.8000112.8Q18 G260 D262 V289Q18-L242 HydrophobicContact CG-CB 4.35Å; Q18-L242 WeakPolarHBondContact CG-O 3.27Å; Q18-L242 PolarHBondContact NE2-O 3.32Å; L242-G260 PolarHBondContact N-O 3.1Å; L242-D262 HydrophobicContact CD1-CB 3.67Å; L242-D262 HydrophobicContact CD2-CB 4.36Å; L242-D262 HydrophobicContact CG-CB 3.86Å; L242-V289 VanDerWaalsContact CB-O 3.26Å; L242-V289 WeakPolarHBondContact CB-O 3.32Å; L242-V289 WeakPolarHBondContact CD1-O 3.42Å
243C98.3Very high92.2Very high2 Ų253.3 Ų53.31%0.01428%0.281CS..EExtended strand (participates in β ladder)trans-151.3148.7-178.755.30000111.9K19 G260 S291 I292K19-C243 HydrophobicContact CG-CB 4.36Å; C243-G260 PolarHBondContact N-O 2.93Å; C243-G260 PolarHBondContact O-N 2.81Å; C243-S291 VanDerWaalsContact SG-CA 3.53Å; C243-I292 HydrophobicContact CB-CG2 3.91Å; C243-I292 VanDerWaalsContact SG-CG2 3.51Å; C243-I292 PolarHBondContact SG-N 3.42Å; C243-I292 VanDerWaalsContact SG-N 3.44Å
244I98.4Very high92.3Very high16 Ų1648.2 Ų48.28%0.08227%0.27CS..EExtended strand (participates in β ladder)trans-138.4138.6-177.8-60.6167.9000107.5V192 A194 L208 L216 I241 L257 L258V192-I244 HydrophobicContact CG1-CD1 3.7Å; V192-I244 HydrophobicContact CG1-CG1 3.96Å; A194-I244 HydrophobicContact CB-CB 4.15Å; A194-I244 HydrophobicContact CB-CG2 4.09Å; L208-I244 HydrophobicContact CD1-CG2 4.39Å; L216-I244 HydrophobicContact CD1-CD1 3.43Å; L216-I244 VanDerWaalsContact CD1-CD1 3.43Å; L216-I244 HydrophobicContact CD1-CG1 4.18Å; I241-I244 HydrophobicContact CG2-CD1 4.11Å; I241-I244 HydrophobicContact CG2-CG1 3.81Å; I244-L257 HydrophobicContact CG2-CD1 3.4Å; I244-L257 VanDerWaalsContact CG2-CD1 3.4Å; I244-L258 CarbonylContact C-O 3.55Å; I244-L258 VanDerWaalsContact CA-O 3.31Å; I244-L258 WeakPolarHBondContact CA-O 3.41Å
245D98.1Very high92.5Very high38 Ų3850.9 Ų50.920%0.20328%0.28CS..EExtended strand (participates in β ladder)trans-141.1164.7169.2-167.132.9000111.2L258 I292 Q293 G294D245-L258 HydrophobicContact CB-CB 4.41Å; D245-L258 PolarHBondContact N-O 3.09Å; D245-L258 PolarHBondContact O-N 3.38Å; D245-I292 HydrophobicContact CB-CG2 4.29Å; D245-Q293 WeakPolarHBondContact OD2-CA 3.49Å; D245-G294 PolarHBondContact OD2-N 3.13Å
246S96.9Very high93Very high10 Ų1043 Ų437%0.0724%0.243CC..EExtended strand (participates in β ladder)trans-125.7117.8176.9-57.60000111.6D256S246-D256 CarbonylContact C-O 3.45Å; S246-D256 VanDerWaalsContact CA-O 3.27Å; S246-D256 WeakPolarHBondContact CA-O 3.29Å
247F95.9Very high93.6Very high44 Ų4436.6 Ų36.619%0.19322%0.216CC..EExtended strand (participates in β ladder)trans-154.7139.4-175.7-179.6-92.9000110.7I249 D256 L258 G294 D303F247-I249 HydrophobicContact CD1-CB 4.06Å; F247-I249 HydrophobicContact CE1-CB 4.34Å; F247-I249 HydrophobicContact CE1-CD1 4.13Å; F247-I249 PolarHBondContact O-N 2.69Å; F247-I249 VanDerWaalsContact O-N 3.12Å; F247-D256 PolarHBondContact N-O 3.32Å; F247-D256 WeakPolarHBondContact O-CA 3.47Å; F247-D256 VanDerWaalsContact O-CB 3.28Å; F247-D256 WeakPolarHBondContact O-CB 3.48Å; F247-D256 PolarHBondContact O-N 2.84Å; F247-L258 HydrophobicContact CB-CD1 3.95Å; F247-G294 VanDerWaalsContact CD2-C 3.42Å; F247-G294 WeakPolarHBondContact CD2-O 3.33Å; F247-G294 VanDerWaalsContact CG-CA 3.46Å; F247-D303 HydrophobicContact CE1-CB 3.95Å; F247-D303 HydrophobicContact CZ-CB 4.09Å
248D94.4Very high94.2Very high38 Ų3831 Ų3120%0.20319%0.192CC..  trans-80.287.9178.3178.213.5000109.7G251 D252 G253 V254D248-G251 WeakPolarHBondContact OD1-CA 3.17Å; D248-G251 PolarHBondContact OD1-N 3.09Å; D248-D252 PolarHBondContact OD1-N 2.88Å; D248-D252 VanDerWaalsContact OD1-N 3.12Å; D248-G253 WeakPolarHBondContact OD2-CA 3.4Å; D248-G253 PolarHBondContact OD2-N 2.89Å; D248-V254 WeakPolarHBondContact CB-O 3.3Å
249I94.2Very high94.8Very high8 Ų829.6 Ų29.64%0.04119%0.186CC..SBendtrans-87.8-26.6179.5-170.961.8000111.2L5 F247 G251 D256 L258 V268 D303 I305 T319L5-I249 HydrophobicContact CD2-CD1 4.28Å; L5-I249 HydrophobicContact CD2-CG1 4.15Å; F247-I249 HydrophobicContact CD1-CB 4.06Å; F247-I249 HydrophobicContact CE1-CB 4.34Å; F247-I249 HydrophobicContact CE1-CD1 4.13Å; F247-I249 PolarHBondContact O-N 2.69Å; F247-I249 VanDerWaalsContact O-N 3.12Å; I249-G251 VanDerWaalsContact C-N 3.33Å; I249-D256 HydrophobicContact CG2-CB 4.12Å; I249-D256 VanDerWaalsContact CG2-OD2 3.28Å; I249-D256 WeakPolarHBondContact CG2-OD2 3.33Å; I249-D256 PolarHBondContact N-OD2 2.91Å; I249-L258 HydrophobicContact CG2-CD2 4.27Å; I249-V268 HydrophobicContact CG2-CG1 3.64Å; I249-D303 HydrophobicContact CD1-CB 3.87Å; I249-I305 HydrophobicContact CD1-CG1 4.41Å; I249-I305 HydrophobicContact CG1-CD1 4.49Å; I249-I305 HydrophobicContact CG1-CG1 4.29Å; I249-T319 HydrophobicContact CD1-CG2 4.1Å
250V89.7Confident95.1Very high52 Ų5229.1 Ų29.132%0.31518%0.181SC..SBendtrans-75.5-25.3176.9179.70000111.6D256V250-D256 WeakPolarHBondContact CG2-OD2 3.29Å; V250-D256 PolarHBondContact N-OD2 3.04Å
251G87.9Confident95.2Very high45 Ų4529.3 Ų29.346%0.46418%0.181SC..  trans80.427176.700000113.7D248 I249D248-G251 WeakPolarHBondContact OD1-CA 3.17Å; D248-G251 PolarHBondContact OD1-N 3.09Å; I249-G251 VanDerWaalsContact C-N 3.33Å
252D88.2Confident95.1Very high95 Ų9530 Ų3051%0.50819%0.185SC..SBendtrans-93.9-0.3-179.570.510.4000113.5D248 V254D248-D252 PolarHBondContact OD1-N 2.88Å; D248-D252 VanDerWaalsContact OD1-N 3.12Å; D252-V254 VanDerWaalsContact C-N 3.33Å; D252-V254 WeakPolarHBondContact OD1-CB 3.26Å; D252-V254 PolarHBondContact OD1-N 3.46Å
253G89Confident94.8Very high65 Ų6528.7 Ų28.767%0.6718%0.178SC*.SBendtrans89.7-7.7-179.600000114D248D248-G253 WeakPolarHBondContact OD2-CA 3.4Å; D248-G253 PolarHBondContact OD2-N 2.89Å
254V91.6Very high94.7Very high77 Ų7728.6 Ų28.647%0.46718%0.178SC..SBendtrans-103.9134.8173.1-177.30000108.2D248 D252 D256 F271D248-V254 WeakPolarHBondContact CB-O 3.3Å; D252-V254 VanDerWaalsContact C-N 3.33Å; D252-V254 WeakPolarHBondContact OD1-CB 3.26Å; D252-V254 PolarHBondContact OD1-N 3.46Å; V254-D256 PolarHBondContact O-N 3.32Å; V254-F271 HydrophobicContact CG1-CD2 4.44Å
255K94.6Very high94.6Very high83 Ų8328.9 Ų28.936%0.36118%0.179SC..PPolyproline II helixtrans-71.3131.2179.8-69.8-176.7173.7-166.50110.6N197 F271N197-K255 HydrophobicContact CB-CD 4.08Å; N197-K255 PolarHBondContact O-NZ 2.72Å; K255-F271 WeakPolarHBondContact O-CE2 3.23Å
256D95.8Very high94.6Very high3 Ų327.1 Ų27.12%0.01617%0.169CC..EExtended strand (participates in β ladder)trans-79.9160.5168.4-53.8-70.3000110.8S246 F247 I249 V250 V254 V268 Y269 S270S246-D256 CarbonylContact C-O 3.45Å; S246-D256 VanDerWaalsContact CA-O 3.27Å; S246-D256 WeakPolarHBondContact CA-O 3.29Å; F247-D256 PolarHBondContact N-O 3.32Å; F247-D256 WeakPolarHBondContact O-CA 3.47Å; F247-D256 VanDerWaalsContact O-CB 3.28Å; F247-D256 WeakPolarHBondContact O-CB 3.48Å; F247-D256 PolarHBondContact O-N 2.84Å; I249-D256 HydrophobicContact CG2-CB 4.12Å; I249-D256 VanDerWaalsContact CG2-OD2 3.28Å; I249-D256 WeakPolarHBondContact CG2-OD2 3.33Å; I249-D256 PolarHBondContact N-OD2 2.91Å; V250-D256 WeakPolarHBondContact CG2-OD2 3.29Å; V250-D256 PolarHBondContact N-OD2 3.04Å; V254-D256 PolarHBondContact O-N 3.32Å; D256-V268 HydrophobicContact CB-CG1 3.95Å; D256-Y269 WeakPolarHBondContact CA-O 3.22Å; D256-S270 WeakPolarHBondContact OD1-CA 3.31Å; D256-S270 WeakPolarHBondContact OD1-CB 3.46Å; D256-S270 PolarHBondContact OD1-OG 3.42Å
257L97.4Very high94.6Very high1 Ų126.6 Ų26.61%0.00517%0.166CC..EExtended strand (participates in β ladder)trans-99.6117176.2-176.759.7000110L208 L216 W230 I244 V259 V268 Y269 F271L208-L257 HydrophobicContact CD1-CD1 3.63Å; L208-L257 HydrophobicContact CD2-CD2 4.3Å; L216-L257 HydrophobicContact CD2-CD2 3.33Å; L216-L257 HydrophobicContact CD2-CG 4.26Å; L216-L257 HydrophobicContact CG-CD2 4.31Å; W230-L257 HydrophobicContact CH2-CD2 3.82Å; I244-L257 HydrophobicContact CG2-CD1 3.4Å; I244-L257 VanDerWaalsContact CG2-CD1 3.4Å; L257-V259 HydrophobicContact CG-CG2 4.04Å; L257-V268 WeakPolarHBondContact O-CA 3.29Å; L257-Y269 PolarHBondContact N-O 2.99Å; L257-Y269 PolarHBondContact O-N 2.93Å; L257-F271 HydrophobicContact CB-CZ 4.33Å
258L98.3Very high94.7Very high0 Ų024.5 Ų24.50%016%0.157CC..EExtended strand (participates in β ladder)trans-99.3126.6179.2-47.5-175.9000108.9I244 D245 F247 I249 V268 I292 I305I244-L258 CarbonylContact C-O 3.55Å; I244-L258 VanDerWaalsContact CA-O 3.31Å; I244-L258 WeakPolarHBondContact CA-O 3.41Å; D245-L258 HydrophobicContact CB-CB 4.41Å; D245-L258 PolarHBondContact N-O 3.09Å; D245-L258 PolarHBondContact O-N 3.38Å; F247-L258 HydrophobicContact CB-CD1 3.95Å; I249-L258 HydrophobicContact CG2-CD2 4.27Å; L258-V268 HydrophobicContact CD2-CB 4.48Å; L258-V268 HydrophobicContact CD2-CG1 4.08Å; L258-V268 HydrophobicContact CD2-CG2 3.97Å; L258-I292 HydrophobicContact CB-CD1 3.73Å; L258-I292 HydrophobicContact CB-CG1 4.07Å; L258-I305 HydrophobicContact CD1-CG1 4.11Å; L258-I305 HydrophobicContact CD1-CG2 4.22Å; L258-I305 HydrophobicContact CD2-CD1 3.85Å; L258-I305 HydrophobicContact CD2-CG1 4.23Å
259V98.4Very high94.8Very high0 Ų023.5 Ų23.50%015%0.15CC..EExtended strand (participates in β ladder)trans-128.4129.3-175.4-173.80000110.4L216 I241 L257 V266 E267 Y269L216-V259 HydrophobicContact CD2-CG2 3.95Å; I241-V259 HydrophobicContact CD1-CG1 4.08Å; I241-V259 HydrophobicContact CG1-CG1 4.27Å; I241-V259 HydrophobicContact CG2-CG1 3.69Å; L257-V259 HydrophobicContact CG-CG2 4.04Å; V259-V266 WeakPolarHBondContact O-CA 3.37Å; V259-E267 HydrophobicContact CB-CB 4.28Å; V259-E267 PolarHBondContact N-O 3.14Å; V259-E267 PolarHBondContact O-N 3.07Å; V259-Y269 HydrophobicContact CG2-CD2 4.16Å; V259-Y269 HydrophobicContact CG2-CE2 4.16Å
260G98.3Very high94.8Very high0 Ų023.3 Ų23.30%015%0.15CC..EExtended strand (participates in β ladder)trans-115.4131.7173.300000112.1L242 C243L242-G260 PolarHBondContact N-O 3.1Å; C243-G260 PolarHBondContact N-O 2.93Å; C243-G260 PolarHBondContact O-N 2.81Å
261R97.7Very high94.9Very high5 Ų522.5 Ų22.52%0.01914%0.142CC..EExtended strand (participates in β ladder)trans-110.1161.2-174.5-60.6-170.8-178.8-94.5-4.2114.2G214 G239 G240 D263 G264 M265 E267 V289G214-R261 PolarHBondContact O-NH1 3.36Å; G239-R261 WeakPolarHBondContact O-CD 3.32Å; G239-R261 PolarHBondContact O-NH1 3.16Å; G240-R261 CarbonylContact O-C 3.53Å; G240-R261 VanDerWaalsContact O-CA 3.27Å; G240-R261 WeakPolarHBondContact O-CA 3.43Å; R261-D263 VanDerWaalsContact C-N 3.25Å; R261-D263 WeakPolarHBondContact CB-OD1 3.48Å; R261-D263 PolarHBondContact O-N 3.28Å; R261-G264 PolarHBondContact O-N 3.37Å; R261-M265 HydrophobicContact CB-CB 4.2Å; R261-M265 HydrophobicContact CG-CB 4.34Å; R261-M265 PolarHBondContact N-O 2.83Å; R261-E267 IonicContact CZ-OE1 3.87Å; R261-E267 IonicContact CZ-OE2 2.67Å; R261-E267 IonicContact NE-OE1 3.42Å; R261-E267 PolarHBondContact NE-OE1 3.19Å; R261-E267 IonicContact NE-OE2 2.73Å; R261-E267 PolarHBondContact NE-OE2 3.4Å; R261-E267 IonicContact NH2-OE1 3.63Å; R261-E267 PolarHBondContact NH2-OE1 3.47Å; R261-E267 IonicContact NH2-OE2 3.63Å; R261-E267 PolarHBondContact NH2-OE2 3.41Å; R261-V289 PolarHBondContact O-N 3.2Å
262D94.8Very high94.8Very high16 Ų1623.1 Ų23.19%0.08613%0.134CC..THydrogen-bonded Turntrans-74.1-8177.673.98.4000114.9G239 G240 L242 S288 K384 R453G239-D262 VanDerWaalsContact C-OD1 3.31Å; G239-D262 WeakPolarHBondContact CA-OD1 3.45Å; G240-D262 PolarHBondContact N-OD1 2.94Å; G240-D262 PolarHBondContact N-OD2 2.84Å; G240-D262 PolarHBondContact O-N 2.97Å; L242-D262 HydrophobicContact CD1-CB 3.67Å; L242-D262 HydrophobicContact CD2-CB 4.36Å; L242-D262 HydrophobicContact CG-CB 3.86Å; D262-S288 PolarHBondContact O-OG 3Å; D262-K384 IonicContact OD2-NZ 3.59Å; D262-K384 PolarHBondContact OD2-NZ 3.44Å; D262-R453 PolarHBondContact O-NE 2.82Å
263D93.3Very high94.6Very high5 Ų527.1 Ų27.13%0.02716%0.156CC..THydrogen-bonded Turntrans-96.4-0.6171.166.9-14.2000112.3G239 R261 M265 M284 K422G239-D263 PolarHBondContact N-OD1 2.73Å; G239-D263 PolarHBondContact N-OD2 2.81Å; R261-D263 VanDerWaalsContact C-N 3.25Å; R261-D263 WeakPolarHBondContact CB-OD1 3.48Å; R261-D263 PolarHBondContact O-N 3.28Å; D263-M265 WeakPolarHBondContact OD1-CB 3.41Å; D263-M265 PolarHBondContact OD1-N 2.85Å; D263-M284 WeakPolarHBondContact O-CE 3.25Å; D263-K422 IonicContact OD2-NZ 2.75Å
264G95.1Very high94.4Very high0 Ų027.2 Ų27.20%015%0.15CC..SBendtrans94.7-1.2-179.700000114.8R261 V266 L285 E287R261-G264 PolarHBondContact O-N 3.37Å; G264-V266 PolarHBondContact O-N 2.68Å; G264-L285 VanDerWaalsContact O-CB 3.3Å; G264-L285 WeakPolarHBondContact O-CB 3.28Å; G264-L285 PolarHBondContact O-N 3.08Å; G264-E287 WeakPolarHBondContact CA-O 3.43Å
265M97Very high94Very high22 Ų2229.1 Ų29.111%0.10816%0.158CC..EExtended strand (participates in β ladder)trans-70.6131.7176.6-169.762.165.200111.6R261 D263 E267 D282 M284R261-M265 HydrophobicContact CB-CB 4.2Å; R261-M265 HydrophobicContact CG-CB 4.34Å; R261-M265 PolarHBondContact N-O 2.83Å; D263-M265 WeakPolarHBondContact OD1-CB 3.41Å; D263-M265 PolarHBondContact OD1-N 2.85Å; M265-E267 HydrophobicContact CG-CG 3.78Å; M265-D282 HydrophobicContact SD-CB 3.8Å; M265-M284 HydrophobicContact CE-CB 4.18Å; M265-M284 HydrophobicContact CE-SD 3.87Å
266V98.1Very high93.8Very high0 Ų030.7 Ų30.70%017%0.166CC..EExtended strand (participates in β ladder)trans-108.4131.8168.3178.40000108V259 G264 D282 Q283 L285 V289 I292 V307 L317V259-V266 WeakPolarHBondContact O-CA 3.37Å; G264-V266 PolarHBondContact O-N 2.68Å; V266-D282 CarbonylContact O-C 3.53Å; V266-D282 VanDerWaalsContact O-CA 3.22Å; V266-D282 WeakPolarHBondContact O-CA 3.02Å; V266-Q283 PolarHBondContact N-O 3.11Å; V266-Q283 PolarHBondContact O-N 2.83Å; V266-L285 HydrophobicContact CG2-CD1 3.84Å; V266-L285 HydrophobicContact CG2-CG 4.26Å; V266-V289 HydrophobicContact CG2-CG2 3.91Å; V266-I292 HydrophobicContact CG1-CD1 3.86Å; V266-V307 HydrophobicContact CG2-CG1 4.32Å; V266-V307 HydrophobicContact CG2-CG2 4.1Å; V266-L317 HydrophobicContact CB-CD1 4.37Å; V266-L317 HydrophobicContact CG1-CD1 3.94Å
267E97.4Very high93.7Very high0 Ų031.9 Ų31.90%017%0.174CC..EExtended strand (participates in β ladder)trans-130.9145.4-176.9-54.2172.8167.700111.2R238 V259 R261 M265 Y269 L279 F281R238-E267 WeakPolarHBondContact CD-OE1 3.2Å; R238-E267 IonicContact CZ-OE1 3.35Å; R238-E267 IonicContact NE-OE1 3.79Å; R238-E267 VanDerWaalsContact NH1-CD 3.26Å; R238-E267 IonicContact NH1-OE1 3.99Å; R238-E267 PolarHBondContact NH1-OE1 2.92Å; V259-E267 HydrophobicContact CB-CB 4.28Å; V259-E267 PolarHBondContact N-O 3.14Å; V259-E267 PolarHBondContact O-N 3.07Å; R261-E267 IonicContact CZ-OE1 3.87Å; R261-E267 IonicContact CZ-OE2 2.67Å; R261-E267 IonicContact NE-OE1 3.42Å; R261-E267 PolarHBondContact NE-OE1 3.19Å; R261-E267 IonicContact NE-OE2 2.73Å; R261-E267 PolarHBondContact NE-OE2 3.4Å; R261-E267 IonicContact NH2-OE1 3.63Å; R261-E267 PolarHBondContact NH2-OE1 3.47Å; R261-E267 IonicContact NH2-OE2 3.63Å; R261-E267 PolarHBondContact NH2-OE2 3.41Å; M265-E267 HydrophobicContact CG-CG 3.78Å; E267-Y269 HydrophobicContact CB-CD2 4.27Å; E267-Y269 HydrophobicContact CB-CE2 3.6Å; E267-Y269 HydrophobicContact CG-CE2 4.4Å; E267-Y269 WeakPolarHBondContact OE2-CE2 3.38Å; E267-Y269 PolarHBondContact OE2-OH 2.88Å; E267-L279 HydrophobicContact CB-CD1 3.94Å; E267-L279 HydrophobicContact CG-CD1 4.36Å; E267-F281 WeakPolarHBondContact CA-O 3.4Å
268V97.4Very high93.5Very high0 Ų034.2 Ų34.20%019%0.189CC..EExtended strand (participates in β ladder)trans-122.2122.7172.2-1770000108.7I249 D256 L257 L258 R280 F281 I305I249-V268 HydrophobicContact CG2-CG1 3.64Å; D256-V268 HydrophobicContact CB-CG1 3.95Å; L257-V268 WeakPolarHBondContact O-CA 3.29Å; L258-V268 HydrophobicContact CD2-CB 4.48Å; L258-V268 HydrophobicContact CD2-CG1 4.08Å; L258-V268 HydrophobicContact CD2-CG2 3.97Å; V268-R280 PolarHBondContact O-N 3.08Å; V268-F281 HydrophobicContact CB-CB 4.06Å; V268-F281 HydrophobicContact CG2-CB 4.1Å; V268-F281 HydrophobicContact CG2-CD1 3.97Å; V268-F281 HydrophobicContact CG2-CG 4.45Å; V268-F281 PolarHBondContact N-O 2.97Å; V268-F281 PolarHBondContact O-N 3.33Å; V268-I305 HydrophobicContact CG2-CD1 3.43Å; V268-I305 VanDerWaalsContact CG2-CD1 3.43Å
269Y96.2Very high93.4Very high17 Ų1736.7 Ų36.77%0.06720%0.202CC..EExtended strand (participates in β ladder)trans-113126.4172.3-60.5-99.6000110.2I232 D256 L257 V259 E267 P277 V278 L279I232-Y269 HydrophobicContact CD1-CD1 3.78Å; I232-Y269 HydrophobicContact CD1-CE1 3.75Å; I232-Y269 HydrophobicContact CD1-CE2 4.5Å; I232-Y269 HydrophobicContact CD1-CG 4.2Å; I232-Y269 HydrophobicContact CG2-CE1 4.35Å; D256-Y269 WeakPolarHBondContact CA-O 3.22Å; L257-Y269 PolarHBondContact N-O 2.99Å; L257-Y269 PolarHBondContact O-N 2.93Å; V259-Y269 HydrophobicContact CG2-CD2 4.16Å; V259-Y269 HydrophobicContact CG2-CE2 4.16Å; E267-Y269 HydrophobicContact CB-CD2 4.27Å; E267-Y269 HydrophobicContact CB-CE2 3.6Å; E267-Y269 HydrophobicContact CG-CE2 4.4Å; E267-Y269 WeakPolarHBondContact OE2-CE2 3.38Å; E267-Y269 PolarHBondContact OE2-OH 2.88Å; Y269-P277 HydrophobicContact CD1-CB 4.25Å; Y269-P277 HydrophobicContact CG-CB 4.46Å; Y269-V278 VanDerWaalsContact CA-O 3.29Å; Y269-V278 WeakPolarHBondContact CA-O 3.32Å; Y269-L279 HydrophobicContact CD1-CB 4Å; Y269-L279 HydrophobicContact CD1-CD1 4.36Å; Y269-L279 HydrophobicContact CE1-CB 3.73Å; Y269-L279 HydrophobicContact CE1-CD1 3.91Å; Y269-L279 HydrophobicContact CE1-CG 4.4Å; Y269-L279 HydrophobicContact CE2-CD1 4.09Å
270S94.6Very high93.2Very high4 Ų440.9 Ų40.93%0.02822%0.217CC..EExtended strand (participates in β ladder)trans-96.1165.9166.7-54.80000109.6D256 P277 V278 R280D256-S270 WeakPolarHBondContact OD1-CA 3.31Å; D256-S270 WeakPolarHBondContact OD1-CB 3.46Å; D256-S270 PolarHBondContact OD1-OG 3.42Å; S270-P277 CarbonylContact O-C 3.52Å; S270-P277 WeakPolarHBondContact O-CA 3.41Å; S270-V278 PolarHBondContact N-O 3.22Å; S270-V278 PolarHBondContact O-N 3.38Å; S270-R280 WeakPolarHBondContact OG-CG 3.25Å
271F92.1Very high93.1Very high34 Ų3442.3 Ų42.315%0.14922%0.224CC..EExtended strand (participates in β ladder)trans-99.7137.1176.6-61.7-80000110.6H196 W230 V254 K255 L257 E276 P277H196-F271 AromaticContact CE1-CZ 3.83Å; W230-F271 AromaticContact CZ2-CE1 3.76Å; W230-F271 HydrophobicContact CZ2-CE1 3.76Å; W230-F271 HydrophobicContact CZ2-CZ 4.23Å; V254-F271 HydrophobicContact CG1-CD2 4.44Å; K255-F271 WeakPolarHBondContact O-CE2 3.23Å; L257-F271 HydrophobicContact CB-CZ 4.33Å; F271-E276 WeakPolarHBondContact CA-O 3.18Å; F271-P277 HydrophobicContact CD1-CB 4.4Å; F271-P277 HydrophobicContact CE1-CB 4.14Å
272D86.4Confident93Very high58 Ų5845.2 Ų45.231%0.3124%0.24SC..  trans-82.9-174173.276.9-2000112.1A274 N275 E276 V278D272-A274 PolarHBondContact O-N 3.5Å; D272-A274 WeakPolarHBondContact OD1-CA 3.39Å; D272-A274 WeakPolarHBondContact OD1-CB 3.35Å; D272-A274 PolarHBondContact OD1-N 3.42Å; D272-N275 PolarHBondContact O-N 3.28Å; D272-N275 PolarHBondContact OD1-N 3.05Å; D272-N275 VanDerWaalsContact OD1-N 3.12Å; D272-E276 PolarHBondContact N-O 3.38Å; D272-E276 PolarHBondContact OD1-N 2.76Å; D272-V278 HydrophobicContact CB-CG2 4.05Å
273N83.4Confident93Very high179 Ų17946.4 Ų46.496%0.95725%0.245SC*.THydrogen-bonded Turntrans-64.8-19179.5-66.3-25.1000113.7N275N273-N275 VanDerWaalsContact C-N 3.33Å
274A83.8Confident93.1Very high67 Ų6750.7 Ų50.755%0.55427%0.266SS*.THydrogen-bonded Turntrans-91.74.2175.300000112.2D272 E276D272-A274 PolarHBondContact O-N 3.5Å; D272-A274 WeakPolarHBondContact OD1-CA 3.39Å; D272-A274 WeakPolarHBondContact OD1-CB 3.35Å; D272-A274 PolarHBondContact OD1-N 3.42Å; A274-E276 HydrophobicContact CB-CG 4.23Å; A274-E276 PolarHBondContact O-N 3.17Å
275N84.5Confident92.9Very high117 Ų11751 Ų5163%0.62627%0.268SS*.SBendtrans59.727.7-170.2-63.1-38000113.4D272 N273D272-N275 PolarHBondContact O-N 3.28Å; D272-N275 PolarHBondContact OD1-N 3.05Å; D272-N275 VanDerWaalsContact OD1-N 3.12Å; N273-N275 VanDerWaalsContact C-N 3.33Å
276E89.8Confident92.5Very high116 Ų11654 Ų5454%0.54229%0.291SS..  trans-90.2138.3172.1-65.9-170.4170.200110.2F271 D272 A274F271-E276 WeakPolarHBondContact CA-O 3.18Å; D272-E276 PolarHBondContact N-O 3.38Å; D272-E276 PolarHBondContact OD1-N 2.76Å; A274-E276 HydrophobicContact CB-CG 4.23Å; A274-E276 PolarHBondContact O-N 3.17Å
277P93.7Very high92.2Very high28 Ų2854.6 Ų54.618%0.18229%0.293CS..EExtended strand (participates in β ladder)trans-73131.4-179.529.6-34.9000111.6W230 I232 Y269 S270 F271W230-P277 HydrophobicContact CD2-CG 3.95Å; W230-P277 HydrophobicContact CE3-CG 3.8Å; W230-P277 HydrophobicContact CH2-CG 4.28Å; W230-P277 HydrophobicContact CZ2-CG 4.39Å; W230-P277 HydrophobicContact CZ3-CG 3.99Å; I232-P277 HydrophobicContact CD1-CB 3.65Å; I232-P277 HydrophobicContact CD1-CG 3.43Å; I232-P277 VanDerWaalsContact CD1-CG 3.43Å; I232-P277 HydrophobicContact CG1-CB 4.32Å; I232-P277 HydrophobicContact CG1-CG 3.53Å; Y269-P277 HydrophobicContact CD1-CB 4.25Å; Y269-P277 HydrophobicContact CG-CB 4.46Å; S270-P277 CarbonylContact O-C 3.52Å; S270-P277 WeakPolarHBondContact O-CA 3.41Å; F271-P277 HydrophobicContact CD1-CB 4.4Å; F271-P277 HydrophobicContact CE1-CB 4.14Å
278V93.8Very high92.1Very high51 Ų5154.7 Ų54.731%0.30929%0.294SS..EExtended strand (participates in β ladder)trans-123124.3178.3-179.70000109.3Y269 S270 D272 R280Y269-V278 VanDerWaalsContact CA-O 3.29Å; Y269-V278 WeakPolarHBondContact CA-O 3.32Å; S270-V278 PolarHBondContact N-O 3.22Å; S270-V278 PolarHBondContact O-N 3.38Å; D272-V278 HydrophobicContact CB-CG2 4.05Å; V278-R280 PolarHBondContact O-N 2.81Å
279L94.9Very high92.2Very high52 Ų5254.7 Ų54.727%0.27229%0.294SS..EExtended strand (participates in β ladder)trans-63.7123.3177.2-17768.7000110.3E267 Y269 F281E267-L279 HydrophobicContact CB-CD1 3.94Å; E267-L279 HydrophobicContact CG-CD1 4.36Å; Y269-L279 HydrophobicContact CD1-CB 4Å; Y269-L279 HydrophobicContact CD1-CD1 4.36Å; Y269-L279 HydrophobicContact CE1-CB 3.73Å; Y269-L279 HydrophobicContact CE1-CD1 3.91Å; Y269-L279 HydrophobicContact CE1-CG 4.4Å; Y269-L279 HydrophobicContact CE2-CD1 4.09Å; L279-F281 WeakPolarHBondContact CD1-O 3.48Å
280R95Very high92.3Very high87 Ų8754.2 Ų54.233%0.32829%0.293SS..EExtended strand (participates in β ladder)trans-108.3-30.8178.2-64.3-53.9-173.6179.6-8.3113.9D2 P3 V268 S270 V278D2-R280 IonicContact OD1-NH1 3.93Å; P3-R280 HydrophobicContact CG-CB 4.39Å; V268-R280 PolarHBondContact O-N 3.08Å; S270-R280 WeakPolarHBondContact OG-CG 3.25Å; V278-R280 PolarHBondContact O-N 2.81Å
281F95.7Very high92.5Very high31 Ų3154.1 Ų54.114%0.13629%0.292CS..EExtended strand (participates in β ladder)trans-150.4141-176.7173.1-89.6000110P3 L5 E267 V268 L279 Q283 L317P3-F281 HydrophobicContact CG-CB 3.89Å; P3-F281 WeakPolarHBondContact O-CD2 3.45Å; L5-F281 HydrophobicContact CB-CE1 4.5Å; L5-F281 HydrophobicContact CB-CE2 3.94Å; L5-F281 HydrophobicContact CB-CZ 3.87Å; L5-F281 HydrophobicContact CD1-CD1 4.02Å; L5-F281 HydrophobicContact CD1-CD2 4.47Å; L5-F281 HydrophobicContact CD1-CE1 3.94Å; L5-F281 HydrophobicContact CD1-CE2 4.41Å; L5-F281 HydrophobicContact CD1-CG 4.28Å; L5-F281 HydrophobicContact CD1-CZ 4.13Å; L5-F281 HydrophobicContact CG-CE2 4.34Å; L5-F281 HydrophobicContact CG-CZ 4.4Å; E267-F281 WeakPolarHBondContact CA-O 3.4Å; V268-F281 HydrophobicContact CB-CB 4.06Å; V268-F281 HydrophobicContact CG2-CB 4.1Å; V268-F281 HydrophobicContact CG2-CD1 3.97Å; V268-F281 HydrophobicContact CG2-CG 4.45Å; V268-F281 PolarHBondContact N-O 2.97Å; V268-F281 PolarHBondContact O-N 3.33Å; L279-F281 WeakPolarHBondContact CD1-O 3.48Å; F281-Q283 HydrophobicContact CE1-CB 3.61Å; F281-Q283 HydrophobicContact CZ-CB 3.58Å; F281-L317 HydrophobicContact CE1-CD1 3.96Å; F281-L317 HydrophobicContact CZ-CD1 4.35Å
282D95.4Very high92.8Very high66 Ų6652.8 Ų52.835%0.35329%0.287SS..EExtended strand (participates in β ladder)trans-137.5146.6165.661.834.2000111.6K236 R238 M265 V266K236-D282 IonicContact NZ-OD2 2.68Å; R238-D282 IonicContact CZ-OD2 2.93Å; R238-D282 IonicContact NH1-OD2 3.48Å; R238-D282 IonicContact NH2-OD2 2.77Å; R238-D282 PolarHBondContact NH2-OD2 2.92Å; M265-D282 HydrophobicContact SD-CB 3.8Å; V266-D282 CarbonylContact O-C 3.53Å; V266-D282 VanDerWaalsContact O-CA 3.22Å; V266-D282 WeakPolarHBondContact O-CA 3.02Å
283Q95.4Very high93.3Very high40 Ų4051.4 Ų51.419%0.18728%0.278CS..EExtended strand (participates in β ladder)trans-146.5128.6175.3179173.8-19.900110.7V266 F281 L317V266-Q283 PolarHBondContact N-O 3.11Å; V266-Q283 PolarHBondContact O-N 2.83Å; F281-Q283 HydrophobicContact CE1-CB 3.61Å; F281-Q283 HydrophobicContact CZ-CB 3.58Å; Q283-L317 VanDerWaalsContact OE1-CD2 3.25Å
284M94.6Very high94Very high96 Ų9643.3 Ų43.347%0.47324%0.237SC..EExtended strand (participates in β ladder)trans-82.2125.3175.3-171.971.3177.200110.9D263 M265D263-M284 WeakPolarHBondContact O-CE 3.25Å; M265-M284 HydrophobicContact CE-CB 4.18Å; M265-M284 HydrophobicContact CE-SD 3.87Å
285L92.4Very high94.5Very high7 Ų740.1 Ų40.14%0.03721%0.211CC..  trans-100.3160.1163-56.6178.6000109.6G264 V266 E287 V289 V307 T309G264-L285 VanDerWaalsContact O-CB 3.3Å; G264-L285 WeakPolarHBondContact O-CB 3.28Å; G264-L285 PolarHBondContact O-N 3.08Å; V266-L285 HydrophobicContact CG2-CD1 3.84Å; V266-L285 HydrophobicContact CG2-CG 4.26Å; L285-E287 VanDerWaalsContact C-N 3.28Å; L285-E287 PolarHBondContact O-N 3.46Å; L285-V289 HydrophobicContact CD1-CG2 3.87Å; L285-V307 HydrophobicContact CD1-CB 4.43Å; L285-V307 HydrophobicContact CD1-CG1 3.84Å; L285-T309 HydrophobicContact CD1-CG2 4.22Å
286S87.4Confident94.9Very high85 Ų8534.7 Ų34.759%0.59418%0.182SC*.SBendtrans-81.1-4-174.453.10000114.6
287E91.9Very high95.1Very high11 Ų1129.2 Ų29.25%0.05116%0.156CC..SBendtrans-142.2160.1-170.5-66.5-179.6-176.800110.2G264 L285 V289 T309 S311G264-E287 WeakPolarHBondContact CA-O 3.43Å; L285-E287 VanDerWaalsContact C-N 3.28Å; L285-E287 PolarHBondContact O-N 3.46Å; E287-V289 PolarHBondContact O-N 2.92Å; E287-T309 HydrophobicContact CB-CG2 4.44Å; E287-T309 VanDerWaalsContact OE2-CB 3.25Å; E287-T309 WeakPolarHBondContact OE2-CB 3.46Å; E287-T309 PolarHBondContact OE2-OG1 3.19Å; E287-S311 VanDerWaalsContact OE1-CB 3.28Å; E287-S311 WeakPolarHBondContact OE1-CB 3.44Å; E287-S311 PolarHBondContact OE1-OG 3.18Å; E287-S311 VanDerWaalsContact OE2-CB 3.24Å; E287-S311 WeakPolarHBondContact OE2-CB 3.5Å; E287-S311 PolarHBondContact OE2-N 3.4Å; E287-S311 PolarHBondContact OE2-OG 2.9Å
288S96.6Very high94.9Very high3 Ų328.6 Ų28.62%0.02116%0.156CC..  trans-55.8131.7175-58.40000111.5D262 T290 T309 Y310 E399D262-S288 PolarHBondContact O-OG 3Å; S288-T290 PolarHBondContact O-N 3Å; S288-T309 CarbonylContact O-C 3.54Å; S288-T309 VanDerWaalsContact O-CA 3.3Å; S288-T309 WeakPolarHBondContact O-CA 3.37Å; S288-Y310 PolarHBondContact O-N 3.33Å; S288-E399 WeakPolarHBondContact CB-OE2 3.29Å; S288-E399 PolarHBondContact N-OE1 3.09Å; S288-E399 PolarHBondContact OG-OE1 3.4Å; S288-E399 PolarHBondContact OG-OE2 2.93Å
289V98.3Very high94.7Very high0 Ų030 Ų300%016%0.157CC..EExtended strand (participates in β ladder)trans-83.2108.91751740000109.7L242 R261 V266 L285 E287 V307L242-V289 VanDerWaalsContact CB-O 3.26Å; L242-V289 WeakPolarHBondContact CB-O 3.32Å; L242-V289 WeakPolarHBondContact CD1-O 3.42Å; R261-V289 PolarHBondContact O-N 3.2Å; V266-V289 HydrophobicContact CG2-CG2 3.91Å; L285-V289 HydrophobicContact CD1-CG2 3.87Å; E287-V289 PolarHBondContact O-N 2.92Å; V289-V307 HydrophobicContact CB-CG1 4.18Å; V289-V307 HydrophobicContact CG1-CG1 3.35Å; V289-V307 HydrophobicContact CG2-CG1 3.83Å
290T98.1Very high94.3Very high6 Ų631.5 Ų31.54%0.03717%0.166CC..EExtended strand (participates in β ladder)trans-87.7-26.9-17559.40000113.1T16 Q18 K19 S288 S308T16-T290 PolarHBondContact OG1-OG1 3.03Å; Q18-T290 CarbonylContact C-O 3.56Å; Q18-T290 WeakPolarHBondContact CA-O 3.37Å; K19-T290 PolarHBondContact N-O 2.87Å; S288-T290 PolarHBondContact O-N 3Å; T290-S308 PolarHBondContact N-O 2.94Å; T290-S308 PolarHBondContact OG1-O 2.98Å; T290-S308 VanDerWaalsContact OG1-O 3.13Å; T290-S308 PolarHBondContact OG1-OG 2.82Å
291S98.6Very high94Very high2 Ų231 Ų311%0.01418%0.175CC..EExtended strand (participates in β ladder)trans-151.4148.3177.1-54.50000111.1K19 T20 M21 C243 V307 S308K19-S291 VanDerWaalsContact CA-OG 3.27Å; K19-S291 WeakPolarHBondContact CA-OG 3.34Å; K19-S291 PolarHBondContact N-OG 2.77Å; T20-S291 PolarHBondContact N-OG 3.48Å; M21-S291 PolarHBondContact N-OG 3.49Å; C243-S291 VanDerWaalsContact SG-CA 3.53Å; S291-V307 WeakPolarHBondContact O-CA 3.26Å; S291-S308 PolarHBondContact N-O 3.01Å; S291-S308 PolarHBondContact O-N 3.3Å
292I98.6Very high93.8Very high7 Ų733.2 Ų33.24%0.03618%0.184CC..EExtended strand (participates in β ladder)trans-138.9137177.6-169.2164.4000108.9C243 D245 L258 V266 I305 V306 V307C243-I292 HydrophobicContact CB-CG2 3.91Å; C243-I292 VanDerWaalsContact SG-CG2 3.51Å; C243-I292 PolarHBondContact SG-N 3.42Å; C243-I292 VanDerWaalsContact SG-N 3.44Å; D245-I292 HydrophobicContact CB-CG2 4.29Å; L258-I292 HydrophobicContact CB-CD1 3.73Å; L258-I292 HydrophobicContact CB-CG1 4.07Å; V266-I292 HydrophobicContact CG1-CD1 3.86Å; I292-I305 HydrophobicContact CD1-CG2 3.79Å; I292-I305 HydrophobicContact CG1-CG2 3.58Å; I292-V306 CarbonylContact C-O 3.58Å; I292-V306 WeakPolarHBondContact CA-O 3.26Å; I292-V307 HydrophobicContact CG1-CG2 4.27Å
293Q98.1Very high93.7Very high28 Ų2831.2 Ų31.213%0.13117%0.173CC..EExtended strand (participates in β ladder)trans-148.2146.6168.5-73.1-154-3400112.4M21 K22 L23 D245 I305 V306M21-Q293 HydrophobicContact CE-CB 4.38Å; K22-Q293 VanDerWaalsContact CD-NE2 3.34Å; L23-Q293 VanDerWaalsContact CB-OE1 3.32Å; L23-Q293 HydrophobicContact CD1-CB 3.9Å; L23-Q293 HydrophobicContact CG-CB 3.97Å; D245-Q293 WeakPolarHBondContact OD2-CA 3.49Å; Q293-I305 CarbonylContact O-C 3.6Å; Q293-V306 PolarHBondContact N-O 2.79Å; Q293-V306 PolarHBondContact O-N 2.97Å
294G96.6Very high93.7Very high9 Ų929.3 Ų29.39%0.09316%0.164CC..EExtended strand (participates in β ladder)trans-92142.9170.700000112.2D245 F247 E304D245-G294 PolarHBondContact OD2-N 3.13Å; F247-G294 VanDerWaalsContact CD2-C 3.42Å; F247-G294 WeakPolarHBondContact CD2-O 3.33Å; F247-G294 VanDerWaalsContact CG-CA 3.46Å; G294-E304 WeakPolarHBondContact CA-O 3.02Å
295G94.6Very high93.9Very high1 Ų124.7 Ų24.71%0.0114%0.141CC..EExtended strand (participates in β ladder)trans174.1-149.1-179.100000113D303 E304G295-D303 CarbonylContact O-C 3.55Å; G295-D303 WeakPolarHBondContact O-CA 3.28Å; G295-E304 PolarHBondContact N-O 2.96Å; G295-E304 WeakPolarHBondContact O-CG 3.44Å; G295-E304 PolarHBondContact O-N 3.05Å
296C93.8Very high94.2Very high3 Ų324.4 Ų24.42%0.0214%0.14CC..  trans-141.5117.3176.71790000108.2T32 Q33 K299 Y302T32-C296 CarbonylContact C-O 3.55Å; T32-C296 WeakPolarHBondContact CA-O 3.34Å; Q33-C296 WeakPolarHBondContact CB-O 3.49Å; Q33-C296 PolarHBondContact N-O 3.08Å; C296-K299 PolarHBondContact SG-O 3.12Å; C296-Y302 PolarHBondContact SG-O 3.19Å
297V94.2Very high94.7Very high0 Ų020.4 Ų20.40%011%0.111CC..  trans-130-44.4-177.51780000112Y10 L23 T32 Q33 V35 M49 E304 V306Y10-V297 HydrophobicContact CE2-CB 4.37Å; Y10-V297 HydrophobicContact CE2-CG1 4.29Å; L23-V297 HydrophobicContact CD1-CG2 4.44Å; L23-V297 HydrophobicContact CD2-CG2 3.79Å; T32-V297 VanDerWaalsContact CG2-O 3.25Å; T32-V297 WeakPolarHBondContact CG2-O 3.43Å; Q33-V297 HydrophobicContact CB-CG2 4.42Å; V35-V297 HydrophobicContact CG2-CB 4.45Å; V35-V297 HydrophobicContact CG2-CG1 3.74Å; V35-V297 HydrophobicContact CG2-CG2 3.9Å; M49-V297 VanDerWaalsContact CB-O 3.26Å; M49-V297 WeakPolarHBondContact CB-O 3.45Å; M49-V297 HydrophobicContact CG-CG1 3.83Å; M49-V297 WeakPolarHBondContact CG-O 3.4Å; V297-E304 VanDerWaalsContact CB-OE1 3.24Å; V297-E304 WeakPolarHBondContact CB-OE1 3.48Å; V297-E304 PolarHBondContact N-OE1 2.85Å; V297-E304 PolarHBondContact N-OE2 2.89Å; V297-V306 HydrophobicContact CB-CG2 4.36Å; V297-V306 HydrophobicContact CG2-CG2 3.71Å
298G89.1Confident95Very high16 Ų1619.9 Ų19.917%0.16511%0.109CC..SBendtrans-64.9-57.8-17800000112.6Y10 E304Y10-G298 WeakPolarHBondContact OH-CA 3.42Å; Y10-G298 PolarHBondContact OH-N 2.75Å; G298-E304 PolarHBondContact N-OE2 2.84Å
299K88.9Confident95Very high79 Ų7920 Ų2034%0.34311%0.11SC..SBendtrans-145.8132.8-174.6-172.1-177.9-178.3-171.60111.1C296 Y302 E320C296-K299 PolarHBondContact SG-O 3.12Å; K299-Y302 HydrophobicContact CB-CD2 4.37Å; K299-Y302 HydrophobicContact CD-CD2 3.9Å; K299-Y302 HydrophobicContact CD-CE2 3.97Å; K299-Y302 HydrophobicContact CG-CD2 4.19Å; K299-Y302 PolarHBondContact O-N 3.31Å; K299-E320 VanDerWaalsContact CD-CD 3.44Å; K299-E320 WeakPolarHBondContact CD-OE1 3.38Å; K299-E320 VanDerWaalsContact CD-OE2 3.3Å; K299-E320 WeakPolarHBondContact CD-OE2 3.39Å; K299-E320 WeakPolarHBondContact CE-OE1 3.36Å; K299-E320 IonicContact NZ-OE1 2.88Å; K299-E320 PolarHBondContact NZ-OE1 2.9Å
300D87.3Confident95Very high84 Ų8420.6 Ų20.645%0.44911%0.112SC..THydrogen-bonded Turntrans-48.9143.2178.3-66.8-20.1000111.4T32 Y302T32-D300 VanDerWaalsContact CB-OD1 3.3Å; T32-D300 WeakPolarHBondContact CB-OD1 3.41Å; T32-D300 WeakPolarHBondContact CG2-OD1 3.42Å; T32-D300 PolarHBondContact N-OD1 3.48Å; T32-D300 PolarHBondContact OG1-OD1 3.28Å; D300-Y302 PolarHBondContact O-N 3.04Å
301S88.2Confident94.8Very high76 Ų7620.6 Ų20.653%0.53111%0.113SC..THydrogen-bonded Turntrans70.8-2.7178.1-46.90000117.7R30R30-S301 PolarHBondContact O-N 3.07Å
302Y91.6Very high94.7Very high79 Ų7920.5 Ų20.531%0.3111%0.112SC..  trans-104.9115.3169.6-67.8-84.4000109.2C296 K299 D300 E320C296-Y302 PolarHBondContact SG-O 3.19Å; K299-Y302 HydrophobicContact CB-CD2 4.37Å; K299-Y302 HydrophobicContact CD-CD2 3.9Å; K299-Y302 HydrophobicContact CD-CE2 3.97Å; K299-Y302 HydrophobicContact CG-CD2 4.19Å; K299-Y302 PolarHBondContact O-N 3.31Å; D300-Y302 PolarHBondContact O-N 3.04Å; Y302-E320 VanDerWaalsContact CD1-CA 3.47Å; Y302-E320 HydrophobicContact CD1-CB 3.83Å; Y302-E320 HydrophobicContact CD1-CG 4.43Å; Y302-E320 HydrophobicContact CD2-CB 4.31Å; Y302-E320 HydrophobicContact CD2-CG 4.46Å; Y302-E320 HydrophobicContact CE1-CB 4.27Å; Y302-E320 HydrophobicContact CE1-CG 4.42Å; Y302-E320 HydrophobicContact CE2-CG 4.46Å; Y302-E320 HydrophobicContact CG-CB 3.83Å; Y302-E320 HydrophobicContact CG-CG 4.42Å
303D94.2Very high94.6Very high23 Ų2324.6 Ų24.612%0.12313%0.127CC..  trans-71.6144.6175.2-64.5-40.7000108.9R30 F247 I249 G295 T319R30-D303 IonicContact CZ-OD2 3.55Å; R30-D303 IonicContact NE-OD2 2.66Å; R30-D303 IonicContact NH2-OD2 2.76Å; R30-D303 PolarHBondContact NH2-OD2 2.88Å; F247-D303 HydrophobicContact CE1-CB 3.95Å; F247-D303 HydrophobicContact CZ-CB 4.09Å; I249-D303 HydrophobicContact CD1-CB 3.87Å; G295-D303 CarbonylContact O-C 3.55Å; G295-D303 WeakPolarHBondContact O-CA 3.28Å; D303-T319 PolarHBondContact N-OG1 2.98Å; D303-T319 WeakPolarHBondContact O-CB 3.46Å; D303-T319 WeakPolarHBondContact O-CG2 3.47Å; D303-T319 PolarHBondContact O-N 3.3Å; D303-T319 PolarHBondContact O-OG1 3.24Å
304E95.2Very high94.6Very high0 Ų023.3 Ų23.30%012%0.121CC..EExtended strand (participates in β ladder)trans-148.9158.3-174.766.6-177.9-113.700112Y10 G294 G295 V297 G298 V306 L317Y10-E304 WeakPolarHBondContact CE2-OE1 3.43Å; Y10-E304 PolarHBondContact OH-OE1 2.82Å; Y10-E304 PolarHBondContact OH-OE2 2.86Å; G294-E304 WeakPolarHBondContact CA-O 3.02Å; G295-E304 PolarHBondContact N-O 2.96Å; G295-E304 WeakPolarHBondContact O-CG 3.44Å; G295-E304 PolarHBondContact O-N 3.05Å; V297-E304 VanDerWaalsContact CB-OE1 3.24Å; V297-E304 WeakPolarHBondContact CB-OE1 3.48Å; V297-E304 PolarHBondContact N-OE1 2.85Å; V297-E304 PolarHBondContact N-OE2 2.89Å; G298-E304 PolarHBondContact N-OE2 2.84Å; E304-V306 HydrophobicContact CG-CG2 4.08Å; E304-V306 VanDerWaalsContact OE1-CG2 3.23Å; E304-V306 WeakPolarHBondContact OE1-CG2 3.49Å; E304-L317 CarbonylContact C-O 3.57Å; E304-L317 VanDerWaalsContact CA-O 3.25Å; E304-L317 WeakPolarHBondContact CA-O 3.38Å; E304-L317 WeakPolarHBondContact CB-O 3.25Å
305I97.9Very high94.6Very high0 Ų022.9 Ų22.90%012%0.117CC..EExtended strand (participates in β ladder)trans-102117.6168.8-55.3172.9000107.9L5 I249 L258 V268 I292 Q293 V307 G316 L317L5-I305 HydrophobicContact CD1-CD1 3.53Å; L5-I305 HydrophobicContact CD1-CG1 4.22Å; I249-I305 HydrophobicContact CD1-CG1 4.41Å; I249-I305 HydrophobicContact CG1-CD1 4.49Å; I249-I305 HydrophobicContact CG1-CG1 4.29Å; L258-I305 HydrophobicContact CD1-CG1 4.11Å; L258-I305 HydrophobicContact CD1-CG2 4.22Å; L258-I305 HydrophobicContact CD2-CD1 3.85Å; L258-I305 HydrophobicContact CD2-CG1 4.23Å; V268-I305 HydrophobicContact CG2-CD1 3.43Å; V268-I305 VanDerWaalsContact CG2-CD1 3.43Å; I292-I305 HydrophobicContact CD1-CG2 3.79Å; I292-I305 HydrophobicContact CG1-CG2 3.58Å; Q293-I305 CarbonylContact O-C 3.6Å; I305-V307 HydrophobicContact CG2-CG2 3.91Å; I305-G316 CarbonylContact O-C 3.49Å; I305-G316 WeakPolarHBondContact O-CA 3.22Å; I305-L317 HydrophobicContact CB-CB 4.23Å; I305-L317 PolarHBondContact N-O 3.21Å; I305-L317 PolarHBondContact O-N 2.8Å
306V98.3Very high94.7Very high0 Ų022.9 Ų22.90%012%0.116CC..EExtended strand (participates in β ladder)trans-94.4126175.5-172.60000109.1M21 L23 V35 I292 Q293 V297 E304 V314M21-V306 HydrophobicContact CE-CB 4.18Å; M21-V306 HydrophobicContact CE-CG1 3.91Å; M21-V306 VanDerWaalsContact CE-O 3.3Å; M21-V306 WeakPolarHBondContact CE-O 3.42Å; M21-V306 HydrophobicContact SD-CG1 4.21Å; L23-V306 HydrophobicContact CD1-CB 4.45Å; L23-V306 HydrophobicContact CD1-CG2 4.06Å; L23-V306 HydrophobicContact CD2-CB 4.3Å; L23-V306 HydrophobicContact CD2-CG1 4.36Å; L23-V306 HydrophobicContact CD2-CG2 4.12Å; V35-V306 HydrophobicContact CG2-CG1 4.41Å; I292-V306 CarbonylContact C-O 3.58Å; I292-V306 WeakPolarHBondContact CA-O 3.26Å; Q293-V306 PolarHBondContact N-O 2.79Å; Q293-V306 PolarHBondContact O-N 2.97Å; V297-V306 HydrophobicContact CB-CG2 4.36Å; V297-V306 HydrophobicContact CG2-CG2 3.71Å; E304-V306 HydrophobicContact CG-CG2 4.08Å; E304-V306 VanDerWaalsContact OE1-CG2 3.23Å; E304-V306 WeakPolarHBondContact OE1-CG2 3.49Å; V306-V314 HydrophobicContact CG1-CG1 3.87Å
307V98.4Very high94.8Very high1 Ų122.7 Ų22.71%0.00612%0.115CC..EExtended strand (participates in β ladder)trans-123.5138-176.1-173.90000109.4V266 L285 V289 S291 I292 I305 V314 T315V266-V307 HydrophobicContact CG2-CG1 4.32Å; V266-V307 HydrophobicContact CG2-CG2 4.1Å; L285-V307 HydrophobicContact CD1-CB 4.43Å; L285-V307 HydrophobicContact CD1-CG1 3.84Å; V289-V307 HydrophobicContact CB-CG1 4.18Å; V289-V307 HydrophobicContact CG1-CG1 3.35Å; V289-V307 HydrophobicContact CG2-CG1 3.83Å; S291-V307 WeakPolarHBondContact O-CA 3.26Å; I292-V307 HydrophobicContact CG1-CG2 4.27Å; I305-V307 HydrophobicContact CG2-CG2 3.91Å; V307-V314 WeakPolarHBondContact O-CA 3.26Å; V307-T315 PolarHBondContact N-O 3.32Å; V307-T315 PolarHBondContact O-N 3.24Å
308S98.3Very high94.8Very high0 Ų023 Ų230%012%0.117CC..EExtended strand (participates in β ladder)trans-108.8134.3167.3-179.70000109.2I37 T290 S291 W313I37-S308 WeakPolarHBondContact CD1-OG 3.38Å; T290-S308 PolarHBondContact N-O 2.94Å; T290-S308 PolarHBondContact OG1-O 2.98Å; T290-S308 VanDerWaalsContact OG1-O 3.13Å; T290-S308 PolarHBondContact OG1-OG 2.82Å; S291-S308 PolarHBondContact N-O 3.01Å; S291-S308 PolarHBondContact O-N 3.3Å; S308-W313 WeakPolarHBondContact CA-O 3.45Å
309T97.6Very high95Very high7 Ų724.5 Ų24.54%0.04312%0.123CC..EExtended strand (participates in β ladder)trans-101.1168.2173.674.40000112.4T16 L285 E287 S288 S311 G312 W313T16-T309 PolarHBondContact OG1-O 2.73Å; L285-T309 HydrophobicContact CD1-CG2 4.22Å; E287-T309 HydrophobicContact CB-CG2 4.44Å; E287-T309 VanDerWaalsContact OE2-CB 3.25Å; E287-T309 WeakPolarHBondContact OE2-CB 3.46Å; E287-T309 PolarHBondContact OE2-OG1 3.19Å; S288-T309 CarbonylContact O-C 3.54Å; S288-T309 VanDerWaalsContact O-CA 3.3Å; S288-T309 WeakPolarHBondContact O-CA 3.37Å; T309-S311 PolarHBondContact O-N 2.9Å; T309-G312 PolarHBondContact O-N 3.3Å; T309-W313 HydrophobicContact CG2-CB 4.35Å; T309-W313 PolarHBondContact N-O 2.83Å; T309-W313 WeakPolarHBondContact OG1-CB 3.13Å; T309-W313 PolarHBondContact OG1-N 3.28Å
310Y96.9Very high95.1Very high12 Ų1222.8 Ų22.85%0.04712%0.116CC..THydrogen-bonded Turntrans-55.2-46.1179.2175.4-107.6000113.3V15 T16 S288 G312 G380 N382 E399V15-Y310 CarbonylContact C-O 3.56Å; V15-Y310 VanDerWaalsContact CA-O 3.26Å; V15-Y310 WeakPolarHBondContact CA-O 3.15Å; V15-Y310 HydrophobicContact CG1-CD1 4.35Å; V15-Y310 HydrophobicContact CG1-CD2 3.74Å; V15-Y310 HydrophobicContact CG1-CE1 3.99Å; V15-Y310 HydrophobicContact CG1-CE2 3.29Å; V15-Y310 HydrophobicContact CG1-CG 4.25Å; V15-Y310 VanDerWaalsContact CG1-CZ 3.44Å; V15-Y310 VanDerWaalsContact CG1-O 3.3Å; V15-Y310 WeakPolarHBondContact CG1-O 3.09Å; T16-Y310 PolarHBondContact N-O 2.8Å; S288-Y310 PolarHBondContact O-N 3.33Å; Y310-G312 PolarHBondContact O-N 3.32Å; Y310-G312 VanDerWaalsContact O-N 3.16Å; Y310-G380 PolarHBondContact OH-O 3.12Å; Y310-N382 HydrophobicContact CD2-CB 4.25Å; Y310-N382 HydrophobicContact CE1-CB 4.24Å; Y310-N382 HydrophobicContact CE2-CB 3.57Å; Y310-N382 PolarHBondContact OH-N 3.33Å; Y310-E399 WeakPolarHBondContact CB-OE1 3.47Å; Y310-E399 HydrophobicContact CD1-CG 3.58Å; Y310-E399 HydrophobicContact CE1-CG 3.93Å; Y310-E399 HydrophobicContact CG-CG 4.24Å
311S95.3Very high94.9Very high6 Ų622.3 Ų22.34%0.04212%0.118CC..THydrogen-bonded Turntrans-76.53.5179.379.80000114.1Q12 E287 T309 W313Q12-S311 PolarHBondContact NE2-O 3.13Å; E287-S311 VanDerWaalsContact OE1-CB 3.28Å; E287-S311 WeakPolarHBondContact OE1-CB 3.44Å; E287-S311 PolarHBondContact OE1-OG 3.18Å; E287-S311 VanDerWaalsContact OE2-CB 3.24Å; E287-S311 WeakPolarHBondContact OE2-CB 3.5Å; E287-S311 PolarHBondContact OE2-N 3.4Å; E287-S311 PolarHBondContact OE2-OG 2.9Å; T309-S311 PolarHBondContact O-N 2.9Å; S311-W313 VanDerWaalsContact OG-CD1 3.22Å
312G96.1Very high94Very high0 Ų023.9 Ų23.90%012%0.119CC..  trans92.812.6173.200000114.9Q12 V13 G14 T309 Y310 V314Q12-G312 CarbonylContact C-O 3.59Å; Q12-G312 WeakPolarHBondContact CA-O 3.44Å; V13-G312 WeakPolarHBondContact CG2-O 3.17Å; V13-G312 PolarHBondContact N-O 2.79Å; G14-G312 WeakPolarHBondContact O-CA 3.44Å; T309-G312 PolarHBondContact O-N 3.3Å; Y310-G312 PolarHBondContact O-N 3.32Å; Y310-G312 VanDerWaalsContact O-N 3.16Å; G312-V314 PolarHBondContact O-N 3.28Å
313W96.9Very high92.7Very high93 Ų9326.9 Ų26.935%0.35214%0.135SC..EExtended strand (participates in β ladder)trans-67.3125.8170.7-74.299.1000110.4D9 Q12 S308 T309 S311D9-W313 HydrophobicContact CB-CE3 4.35Å; D9-W313 HydrophobicContact CB-CZ3 4.33Å; Q12-W313 HydrophobicContact CB-CD2 4.12Å; Q12-W313 HydrophobicContact CB-CE3 4.07Å; Q12-W313 HydrophobicContact CB-CH2 4.37Å; Q12-W313 HydrophobicContact CB-CZ2 4.41Å; Q12-W313 HydrophobicContact CB-CZ3 4.2Å; Q12-W313 VanDerWaalsContact CD-CE2 3.48Å; Q12-W313 HydrophobicContact CG-CD2 3.99Å; Q12-W313 HydrophobicContact CG-CE3 4.46Å; Q12-W313 HydrophobicContact CG-CG 4.22Å; Q12-W313 HydrophobicContact CG-CZ2 4.38Å; S308-W313 WeakPolarHBondContact CA-O 3.45Å; T309-W313 HydrophobicContact CG2-CB 4.35Å; T309-W313 PolarHBondContact N-O 2.83Å; T309-W313 WeakPolarHBondContact OG1-CB 3.13Å; T309-W313 PolarHBondContact OG1-N 3.28Å; S311-W313 VanDerWaalsContact OG-CD1 3.22Å
314V97.6Very high90.8Very high0 Ų034.2 Ų34.20%017%0.166CC..EExtended strand (participates in β ladder)trans-102.1112.3168.9-1690000108.3Y10 L11 V35 I37 F47 V306 V307 G312Y10-V314 WeakPolarHBondContact CB-O 3.48Å; Y10-V314 HydrophobicContact CD2-CG1 4.26Å; Y10-V314 PolarHBondContact N-O 2.74Å; L11-V314 PolarHBondContact O-N 2.95Å; V35-V314 HydrophobicContact CG1-CG1 4.27Å; I37-V314 HydrophobicContact CD1-CG2 3.54Å; F47-V314 HydrophobicContact CE1-CG1 4.42Å; F47-V314 HydrophobicContact CE1-CG2 4.45Å; F47-V314 HydrophobicContact CZ-CB 4.34Å; F47-V314 HydrophobicContact CZ-CG1 3.99Å; V306-V314 HydrophobicContact CG1-CG1 3.87Å; V307-V314 WeakPolarHBondContact O-CA 3.26Å; G312-V314 PolarHBondContact O-N 3.28Å
315T96.4Very high88.3Confident1 Ų143.6 Ų43.61%0.00621%0.21CC..EExtended strand (participates in β ladder)trans-123.5134.5-172.8-62.30000109.7R7 M8 D9 V307 L317R7-T315 HydrophobicContact CG-CG2 3.61Å; M8-T315 CarbonylContact O-C 3.6Å; D9-T315 WeakPolarHBondContact OD1-CB 3.32Å; D9-T315 WeakPolarHBondContact OD1-CG2 3.37Å; D9-T315 PolarHBondContact OD1-OG1 2.91Å; V307-T315 PolarHBondContact N-O 3.32Å; V307-T315 PolarHBondContact O-N 3.24Å; T315-L317 HydrophobicContact CG2-CD2 4.43Å
316G96.1Very high85.8Confident0 Ų047.7 Ų47.70%024%0.239CC..EExtended strand (participates in β ladder)trans-97139.6168.800000111.2R7 M8 I305R7-G316 CarbonylContact C-O 3.55Å; R7-G316 WeakPolarHBondContact CA-O 3.29Å; M8-G316 PolarHBondContact N-O 3.02Å; M8-G316 PolarHBondContact O-N 3.15Å; I305-G316 CarbonylContact O-C 3.49Å; I305-G316 WeakPolarHBondContact O-CA 3.22Å
317L96.6Very high83.4Confident0 Ų049.8 Ų49.80%026%0.26CS..EExtended strand (participates in β ladder)trans-107.895.6164.8-53.4-178.1000106.9L5 N6 R7 V266 F281 Q283 E304 I305 T315L5-L317 HydrophobicContact CB-CB 3.93Å; L5-L317 HydrophobicContact CD1-CB 4.18Å; N6-L317 CarbonylContact O-C 3.59Å; N6-L317 WeakPolarHBondContact O-CA 3.45Å; R7-L317 HydrophobicContact CB-CD2 4.12Å; R7-L317 HydrophobicContact CG-CD2 4.34Å; V266-L317 HydrophobicContact CB-CD1 4.37Å; V266-L317 HydrophobicContact CG1-CD1 3.94Å; F281-L317 HydrophobicContact CE1-CD1 3.96Å; F281-L317 HydrophobicContact CZ-CD1 4.35Å; Q283-L317 VanDerWaalsContact OE1-CD2 3.25Å; E304-L317 CarbonylContact C-O 3.57Å; E304-L317 VanDerWaalsContact CA-O 3.25Å; E304-L317 WeakPolarHBondContact CA-O 3.38Å; E304-L317 WeakPolarHBondContact CB-O 3.25Å; I305-L317 HydrophobicContact CB-CB 4.23Å; I305-L317 PolarHBondContact N-O 3.21Å; I305-L317 PolarHBondContact O-N 2.8Å; T315-L317 HydrophobicContact CG2-CD2 4.43Å
318T94.6Very high80.6Confident5 Ų556.8 Ų56.83%0.03131%0.306CS..EExtended strand (participates in β ladder)trans-99.6148.3-168.1-175.40000112.8L5 N6 M8 E320L5-T318 WeakPolarHBondContact CA-O 3.23Å; N6-T318 HydrophobicContact CB-CG2 4.17Å; N6-T318 PolarHBondContact N-O 3.45Å; N6-T318 WeakPolarHBondContact O-CG2 3.39Å; N6-T318 PolarHBondContact O-N 3.35Å; M8-T318 HydrophobicContact CE-CG2 4.3Å; T318-E320 HydrophobicContact CG2-CB 3.92Å; T318-E320 PolarHBondContact O-N 3.12Å; T318-E320 PolarHBondContact OG1-N 2.68Å; T318-E320 VanDerWaalsContact OG1-N 3.13Å
319T93.1Very high78.4Confident48 Ų4860.8 Ų60.829%0.29435%0.347SS..SBendtrans-74.5-6.9168.554.70000113.1L5 I249 D303 P321L5-T319 HydrophobicContact CD2-CG2 3.67Å; I249-T319 HydrophobicContact CD1-CG2 4.1Å; D303-T319 PolarHBondContact N-OG1 2.98Å; D303-T319 WeakPolarHBondContact O-CB 3.46Å; D303-T319 WeakPolarHBondContact O-CG2 3.47Å; D303-T319 PolarHBondContact O-N 3.3Å; D303-T319 PolarHBondContact O-OG1 3.24Å; T319-P321 WeakPolarHBondContact O-CD 3.37Å
320E89.8Confident75.8Confident43 Ų4367 Ų6720%0.20138%0.376CS..SBendtrans-63.9126.5175.5-176.3171.1-160.300111.1N6 K299 Y302 T318 I322N6-E320 PolarHBondContact ND2-O 3.5Å; K299-E320 VanDerWaalsContact CD-CD 3.44Å; K299-E320 WeakPolarHBondContact CD-OE1 3.38Å; K299-E320 VanDerWaalsContact CD-OE2 3.3Å; K299-E320 WeakPolarHBondContact CD-OE2 3.39Å; K299-E320 WeakPolarHBondContact CE-OE1 3.36Å; K299-E320 IonicContact NZ-OE1 2.88Å; K299-E320 PolarHBondContact NZ-OE1 2.9Å; Y302-E320 VanDerWaalsContact CD1-CA 3.47Å; Y302-E320 HydrophobicContact CD1-CB 3.83Å; Y302-E320 HydrophobicContact CD1-CG 4.43Å; Y302-E320 HydrophobicContact CD2-CB 4.31Å; Y302-E320 HydrophobicContact CD2-CG 4.46Å; Y302-E320 HydrophobicContact CE1-CB 4.27Å; Y302-E320 HydrophobicContact CE1-CG 4.42Å; Y302-E320 HydrophobicContact CE2-CG 4.46Å; Y302-E320 HydrophobicContact CG-CB 3.83Å; Y302-E320 HydrophobicContact CG-CG 4.42Å; T318-E320 HydrophobicContact CG2-CB 3.92Å; T318-E320 PolarHBondContact O-N 3.12Å; T318-E320 PolarHBondContact OG1-N 2.68Å; T318-E320 VanDerWaalsContact OG1-N 3.13Å; E320-I322 PolarHBondContact O-N 2.62Å
321P83.2Confident73.2Confident75 Ų7574.6 Ų74.649%0.48741%0.411SS..  trans-65.9120.9172.4-18.731.3000111.1T319 H323T319-P321 WeakPolarHBondContact O-CD 3.37Å; P321-H323 PolarHBondContact O-N 2.8Å
322I69.7Low70.7Confident108 Ų10881.8 Ų81.855%0.55445%0.449SS*.SBendtrans-64.9-27.8177.9-64.3168.8000111.4N6 E320N6-I322 HydrophobicContact CB-CD1 3.46Å; N6-I322 VanDerWaalsContact CB-CD1 3.46Å; N6-I322 HydrophobicContact CB-CG1 3.64Å; E320-I322 PolarHBondContact O-N 2.62Å
323H64.4Low68.3Low142 Ų14290.4 Ų90.466%0.65749%0.486SS*.  trans-116.9111.3-178-67.2-124.5000109.8P321P321-H323 PolarHBondContact O-N 2.8Å
324K55Low66.2Low178 Ų17892.3 Ų92.377%0.77450%0.497SS*.  trans-73.9125.3159.2-66.6179.3-177.7175.30106.6S326K324-S326 PolarHBondContact O-N 2.83Å; K324-S326 VanDerWaalsContact O-N 3.08Å
325E41.3Very low64.8Low197 Ų19796.8 Ų96.892%0.92152%0.521SS*.  trans-42.4114.4-177.4-66.5178.1158.900112.2
326S46.2Very low63.6Low86 Ų86103.6 Ų103.660%0.60155%0.553SS**  trans-79132.8167.7-60.10000108.8K324K324-S326 PolarHBondContact O-N 2.83Å; K324-S326 VanDerWaalsContact O-N 3.08Å
327G48.3Very low62.4Low44 Ų44110 Ų11045%0.45458%0.583SS.*  trans-64163.1175.700000112.7G329G327-G329 PolarHBondContact O-N 3.28Å; G327-G329 VanDerWaalsContact O-N 3.13Å
328P39.9Very low61.3Low148 Ų148114.9 Ų114.996%0.96161%0.607SS**THydrogen-bonded Turntrans-66.5115.6-176.926.3-31.1000110.4
329G50.8Low60.7Low83 Ų83119.7 Ų119.786%0.85663%0.629SS**THydrogen-bonded Turntrans121.5-2.4175.200000116.1G327G327-G329 PolarHBondContact O-N 3.28Å; G327-G329 VanDerWaalsContact O-N 3.13Å
330E44.3Very low60.2Low139 Ų139122.2 Ų122.265%0.6564%0.641SS**  trans-89.8114.7169.9-68.7-170150.800110.4
331E41.8Very low59.8Low170 Ų170126.3 Ų126.379%0.79466%0.658SS**  trans-52.1141.4163.9-69.7-179.2160.200109.5K333E331-K333 PolarHBondContact O-N 2.67Å
332L43.4Very low60Low158 Ų158125.7 Ų125.783%0.82765%0.65SS**  trans-56.280.7175.8-76.6156.5000110.8F334L332-F334 PolarHBondContact O-N 2.74Å
333K45.1Very low61Low180 Ų180123.3 Ų123.378%0.78364%0.642SS**  trans-70.3114.6172.2-73.5179.6-178.2172.20106.9E331 N335E331-K333 PolarHBondContact O-N 2.67Å; K333-N335 PolarHBondContact O-N 3.18Å; K333-N335 VanDerWaalsContact O-N 3.16Å
334F52.3Low62.1Low133 Ų133119.9 Ų119.958%0.58364%0.635SS**  trans-41.8124.7165.3-79.8-87.9000109L332 Q336 M338 Q339L332-F334 PolarHBondContact O-N 2.74Å; F334-Q336 PolarHBondContact O-N 3.34Å; F334-M338 HydrophobicContact CD1-SD 3.84Å; F334-M338 HydrophobicContact CE1-SD 4.33Å; F334-Q339 HydrophobicContact CB-CG 3.98Å
335N67.8Low63.8Low95 Ų95115.9 Ų115.951%0.50862%0.621SS.*  trans-50.2130.7178.6-177.46.7000108.6K333 E337 M338 Q339K333-N335 PolarHBondContact O-N 3.18Å; K333-N335 VanDerWaalsContact O-N 3.16Å; N335-E337 PolarHBondContact ND2-OE2 3.44Å; N335-E337 PolarHBondContact O-N 2.75Å; N335-M338 WeakPolarHBondContact O-CA 3.44Å; N335-M338 WeakPolarHBondContact O-CB 3.18Å; N335-M338 PolarHBondContact O-N 3.21Å; N335-Q339 PolarHBondContact O-N 3.28Å
336Q71.4Confident66.3Low144 Ų144114.3 Ų114.367%0.67361%0.607SS**Hα-helixtrans-55.9-29.5-174.6-169164.310.600112F334 Q339 N340F334-Q336 PolarHBondContact O-N 3.34Å; Q336-Q339 PolarHBondContact O-N 2.89Å; Q336-N340 VanDerWaalsContact O-CG 3.26Å; Q336-N340 PolarHBondContact O-N 2.98Å; Q336-N340 PolarHBondContact O-ND2 3.49Å
337E71.3Confident68.5Low134 Ų134115.3 Ų115.363%0.62661%0.605SS**Hα-helixtrans-63.7-41.2172.1-65.5174.4158.600113N335 Q339 N340 K341N335-E337 PolarHBondContact ND2-OE2 3.44Å; N335-E337 PolarHBondContact O-N 2.75Å; E337-Q339 VanDerWaalsContact C-N 3.35Å; E337-N340 PolarHBondContact O-N 3.13Å; E337-K341 WeakPolarHBondContact O-CB 3.36Å; E337-K341 PolarHBondContact O-N 3.01Å
338M74.2Confident70.7Confident103 Ų103118.4 Ų118.451%0.50761%0.608SS.*Hα-helixtrans-66-39.6177.3-170.1176.7-172.700111F334 N335 K341 I342F334-M338 HydrophobicContact CD1-SD 3.84Å; F334-M338 HydrophobicContact CE1-SD 4.33Å; N335-M338 WeakPolarHBondContact O-CA 3.44Å; N335-M338 WeakPolarHBondContact O-CB 3.18Å; N335-M338 PolarHBondContact O-N 3.21Å; M338-K341 PolarHBondContact O-N 3.45Å; M338-I342 HydrophobicContact CG-CD1 4.15Å; M338-I342 VanDerWaalsContact O-CG1 3.26Å; M338-I342 WeakPolarHBondContact O-CG1 3.23Å; M338-I342 PolarHBondContact O-N 3.36Å
339Q81.1Confident73.3Confident106 Ų106115.8 Ų115.850%0.49559%0.585SS.*Hα-helixtrans-64.1-42.2175.3-66.9-173.6-16.200111.9F334 N335 Q336 E337 I342 S343F334-Q339 HydrophobicContact CB-CG 3.98Å; N335-Q339 PolarHBondContact O-N 3.28Å; Q336-Q339 PolarHBondContact O-N 2.89Å; E337-Q339 VanDerWaalsContact C-N 3.35Å; Q339-I342 PolarHBondContact O-N 2.91Å; Q339-S343 PolarHBondContact O-N 3Å; Q339-S343 PolarHBondContact O-OG 3.07Å
340N83Confident75.4Confident101 Ų101117.8 Ų117.854%0.5457%0.572SS.*Hα-helixtrans-64.9-39.4175.5-70-16.3000112.3Q336 E337 S343 S344Q336-N340 VanDerWaalsContact O-CG 3.26Å; Q336-N340 PolarHBondContact O-N 2.98Å; Q336-N340 PolarHBondContact O-ND2 3.49Å; E337-N340 PolarHBondContact O-N 3.13Å; N340-S343 PolarHBondContact O-N 3.2Å; N340-S343 PolarHBondContact O-OG 3.08Å; N340-S344 WeakPolarHBondContact O-CB 3.28Å; N340-S344 PolarHBondContact O-N 2.85Å
341K81.3Confident77.8Confident128 Ų128117 Ų11756%0.55757%0.569SS**Hα-helixtrans-64-44.1175.6-169.3172-176.6175.50111.2E337 M338 S343 S344 L345E337-K341 WeakPolarHBondContact O-CB 3.36Å; E337-K341 PolarHBondContact O-N 3.01Å; M338-K341 PolarHBondContact O-N 3.45Å; K341-S343 PolarHBondContact O-N 2.76Å; K341-S344 PolarHBondContact O-N 2.95Å; K341-L345 HydrophobicContact CG-CD1 4.19Å; K341-L345 WeakPolarHBondContact O-CB 3.34Å; K341-L345 VanDerWaalsContact O-CG 3.28Å; K341-L345 WeakPolarHBondContact O-CG 3.47Å; K341-L345 PolarHBondContact O-N 3.43Å
342I87.6Confident80.4Confident63 Ų63113 Ų11332%0.32355%0.552SS.*Hα-helixtrans-62.2-42.5177-69.6166.7000111.2M338 Q339 L345 R346M338-I342 HydrophobicContact CG-CD1 4.15Å; M338-I342 VanDerWaalsContact O-CG1 3.26Å; M338-I342 WeakPolarHBondContact O-CG1 3.23Å; M338-I342 PolarHBondContact O-N 3.36Å; Q339-I342 PolarHBondContact O-N 2.91Å; I342-L345 PolarHBondContact O-N 2.85Å; I342-R346 WeakPolarHBondContact O-CG 3.4Å; I342-R346 PolarHBondContact O-N 3.21Å
343S89.9Confident82.8Confident57 Ų57110.5 Ų110.540%0.39954%0.536SS..Hα-helixtrans-67.4-40.8179.165.30000112.2Q339 N340 K341 R346 N347Q339-S343 PolarHBondContact O-N 3Å; Q339-S343 PolarHBondContact O-OG 3.07Å; N340-S343 PolarHBondContact O-N 3.2Å; N340-S343 PolarHBondContact O-OG 3.08Å; K341-S343 PolarHBondContact O-N 2.76Å; S343-R346 PolarHBondContact O-N 3.19Å; S343-N347 PolarHBondContact O-N 2.94Å; S343-N347 VanDerWaalsContact O-N 3.14Å
344S88.6Confident85.2Confident71 Ų71109.5 Ų109.550%0.49753%0.529SS..Hα-helixtrans-60.2-46.7173.7-171.80000111.9N340 K341 R346 N347 E348N340-S344 WeakPolarHBondContact O-CB 3.28Å; N340-S344 PolarHBondContact O-N 2.85Å; K341-S344 PolarHBondContact O-N 2.95Å; S344-R346 VanDerWaalsContact C-N 3.31Å; S344-R346 PolarHBondContact O-N 2.89Å; S344-N347 PolarHBondContact O-N 2.94Å; S344-E348 PolarHBondContact O-N 3.36Å
345L89.6Confident87.3Confident93 Ų93108.6 Ų108.649%0.48752%0.524SS..Hα-helixtrans-63-36.1178.5-73.4171000112.5K341 I342 L349K341-L345 HydrophobicContact CG-CD1 4.19Å; K341-L345 WeakPolarHBondContact O-CB 3.34Å; K341-L345 VanDerWaalsContact O-CG 3.28Å; K341-L345 WeakPolarHBondContact O-CG 3.47Å; K341-L345 PolarHBondContact O-N 3.43Å; I342-L345 PolarHBondContact O-N 2.85Å; L345-L349 WeakPolarHBondContact O-CB 3.5Å; L345-L349 PolarHBondContact O-N 2.93Å
346R93.4Very high88.6Confident165 Ų165107.3 Ų107.362%0.62352%0.52SS*.Hα-helixtrans-63.6-47.2174.9-76.2176.1-179.3179.61.2111.8I342 S343 S344 E348 L349 E350I342-R346 WeakPolarHBondContact O-CG 3.4Å; I342-R346 PolarHBondContact O-N 3.21Å; S343-R346 PolarHBondContact O-N 3.19Å; S344-R346 VanDerWaalsContact C-N 3.31Å; S344-R346 PolarHBondContact O-N 2.89Å; R346-E348 VanDerWaalsContact C-N 3.35Å; R346-E348 PolarHBondContact O-N 2.84Å; R346-L349 PolarHBondContact O-N 3.2Å; R346-E350 WeakPolarHBondContact O-CG 3.47Å; R346-E350 PolarHBondContact O-N 2.5Å
347N94.1Very high89.7Confident107 Ų107105 Ų10557%0.57251%0.512SS*.Hα-helixtrans-62.5-42.8178.6-67.9-17.4000111.8S343 S344 E350 H351S343-N347 PolarHBondContact O-N 2.94Å; S343-N347 VanDerWaalsContact O-N 3.14Å; S344-N347 PolarHBondContact O-N 2.94Å; N347-E350 PolarHBondContact O-N 3.26Å; N347-H351 PolarHBondContact O-N 3.46Å; N347-H351 VanDerWaalsContact O-N 3.11Å
348E93.1Very high90.9Very high109 Ų109102.8 Ų102.851%0.50950%0.501SS..Hα-helixtrans-63.8-43.2176.7-174.3175.4-173.200111.5S344 R346 H351 L352S344-E348 PolarHBondContact O-N 3.36Å; R346-E348 VanDerWaalsContact C-N 3.35Å; R346-E348 PolarHBondContact O-N 2.84Å; E348-H351 PolarHBondContact O-N 3.16Å; E348-L352 HydrophobicContact CG-CD1 3.94Å; E348-L352 HydrophobicContact CG-CG 4.39Å; E348-L352 WeakPolarHBondContact O-CB 3.42Å; E348-L352 WeakPolarHBondContact O-CG 3.38Å; E348-L352 PolarHBondContact O-N 2.88Å
349L94.4Very high91.8Very high93 Ų93102.9 Ų102.949%0.48750%0.5SS..Hα-helixtrans-62.1-44.1177.4178.9144.3000112L345 R346 L352 Q353L345-L349 WeakPolarHBondContact O-CB 3.5Å; L345-L349 PolarHBondContact O-N 2.93Å; R346-L349 PolarHBondContact O-N 3.2Å; L349-L352 PolarHBondContact O-N 3.35Å; L349-Q353 VanDerWaalsContact CD2-CD 3.46Å; L349-Q353 HydrophobicContact CD2-CG 4.3Å; L349-Q353 HydrophobicContact CG-CG 4.47Å; L349-Q353 VanDerWaalsContact O-CB 3.28Å; L349-Q353 WeakPolarHBondContact O-CB 3.2Å; L349-Q353 WeakPolarHBondContact O-CG 3.38Å; L349-Q353 PolarHBondContact O-N 2.95Å
350E95.3Very high92.3Very high124 Ų124103.7 Ų103.758%0.57950%0.499SS*.Hα-helixtrans-61-46.2175.9-74.7177.8-171.400111.8R346 N347 Q353 Y354R346-E350 WeakPolarHBondContact O-CG 3.47Å; R346-E350 PolarHBondContact O-N 2.5Å; N347-E350 PolarHBondContact O-N 3.26Å; E350-Q353 PolarHBondContact O-N 2.66Å; E350-Y354 PolarHBondContact O-N 3.18Å
351H95.5Very high92.8Very high123 Ų123104.8 Ų104.857%0.56950%0.501SS*.Hα-helixtrans-62.9-44.9177.8174.8-92000112.1N347 E348 Y354 K355N347-H351 PolarHBondContact O-N 3.46Å; N347-H351 VanDerWaalsContact O-N 3.11Å; E348-H351 PolarHBondContact O-N 3.16Å; H351-Y354 PolarHBondContact O-N 3.18Å; H351-K355 PolarHBondContact O-N 2.88Å; H351-K355 VanDerWaalsContact O-N 3.08Å
352L95.1Very high93.3Very high85 Ų85101.9 Ų101.945%0.44549%0.492SS..Hα-helixtrans-65.9-40177.4-73.6174.5000112E348 L349 K355 V356E348-L352 HydrophobicContact CG-CD1 3.94Å; E348-L352 HydrophobicContact CG-CG 4.39Å; E348-L352 WeakPolarHBondContact O-CB 3.42Å; E348-L352 WeakPolarHBondContact O-CG 3.38Å; E348-L352 PolarHBondContact O-N 2.88Å; L349-L352 PolarHBondContact O-N 3.35Å; L352-K355 PolarHBondContact O-N 3.45Å; L352-V356 WeakPolarHBondContact O-CB 3.43Å; L352-V356 VanDerWaalsContact O-CG2 3.25Å; L352-V356 WeakPolarHBondContact O-CG2 3.4Å; L352-V356 PolarHBondContact O-N 2.86Å
353Q94.4Very high93.4Very high106 Ų106102.9 Ų102.950%0.49549%0.492SS..Hα-helixtrans-59.8-47.4175.6-79.9177.9-10.100111.5L349 E350 K355 V356 L357L349-Q353 VanDerWaalsContact CD2-CD 3.46Å; L349-Q353 HydrophobicContact CD2-CG 4.3Å; L349-Q353 HydrophobicContact CG-CG 4.47Å; L349-Q353 VanDerWaalsContact O-CB 3.28Å; L349-Q353 WeakPolarHBondContact O-CB 3.2Å; L349-Q353 WeakPolarHBondContact O-CG 3.38Å; L349-Q353 PolarHBondContact O-N 2.95Å; E350-Q353 PolarHBondContact O-N 2.66Å; Q353-K355 PolarHBondContact O-N 3.31Å; Q353-V356 PolarHBondContact O-N 2.88Å; Q353-L357 WeakPolarHBondContact O-CB 3.48Å; Q353-L357 VanDerWaalsContact O-CG 3.26Å; Q353-L357 WeakPolarHBondContact O-CG 3.44Å; Q353-L357 PolarHBondContact O-N 3.39Å
354Y96.1Very high93.4Very high159 Ų159105.6 Ų105.662%0.62450%0.498SS*.Hα-helixtrans-58.5-49.1176.9-179.9-97.3000111.7E350 H351 V356 L357 Q358E350-Y354 PolarHBondContact O-N 3.18Å; H351-Y354 PolarHBondContact O-N 3.18Å; Y354-V356 PolarHBondContact O-N 2.95Å; Y354-L357 PolarHBondContact O-N 3.47Å; Y354-Q358 PolarHBondContact O-N 3.26Å
355K96.4Very high93.6Very high114 Ų114108.5 Ų108.550%0.49650%0.504SS..Hα-helixtrans-61.4-43.1179.4-172.2175.1-178.4179.10112.4H351 L352 Q353 Q358 E359H351-K355 PolarHBondContact O-N 2.88Å; H351-K355 VanDerWaalsContact O-N 3.08Å; L352-K355 PolarHBondContact O-N 3.45Å; Q353-K355 PolarHBondContact O-N 3.31Å; K355-Q358 PolarHBondContact O-N 2.96Å; K355-E359 PolarHBondContact O-N 3.2Å
356V94.5Very high93.6Very high69 Ų69106.8 Ų106.842%0.41850%0.5SS..Hα-helixtrans-66.2-38.4178.2168.70000111.3L352 Q353 Y354 E359 R360L352-V356 WeakPolarHBondContact O-CB 3.43Å; L352-V356 VanDerWaalsContact O-CG2 3.25Å; L352-V356 WeakPolarHBondContact O-CG2 3.4Å; L352-V356 PolarHBondContact O-N 2.86Å; Q353-V356 PolarHBondContact O-N 2.88Å; Y354-V356 PolarHBondContact O-N 2.95Å; V356-E359 PolarHBondContact O-N 2.63Å; V356-R360 HydrophobicContact CG1-CG 4.36Å; V356-R360 WeakPolarHBondContact O-CB 3.43Å; V356-R360 WeakPolarHBondContact O-CG 3.34Å; V356-R360 PolarHBondContact O-N 2.82Å
357L94.9Very high93.3Very high95 Ų95101.2 Ų101.250%0.49749%0.486SS..Hα-helixtrans-62.9-46.6175.8-74.8168.7000111.4Q353 Y354 E359 R360 E361Q353-L357 WeakPolarHBondContact O-CB 3.48Å; Q353-L357 VanDerWaalsContact O-CG 3.26Å; Q353-L357 WeakPolarHBondContact O-CG 3.44Å; Q353-L357 PolarHBondContact O-N 3.39Å; Y354-L357 PolarHBondContact O-N 3.47Å; L357-E359 PolarHBondContact O-N 3.2Å; L357-R360 WeakPolarHBondContact O-CB 3.49Å; L357-R360 PolarHBondContact O-N 2.81Å; L357-E361 PolarHBondContact O-N 2.81Å
358Q95.7Very high93.1Very high88 Ų88103.7 Ų103.741%0.41149%0.494SS..Hα-helixtrans-58.4-47.5176.7-172.7179.3900111.8Y354 K355 R360 E361 N362Y354-Q358 PolarHBondContact O-N 3.26Å; K355-Q358 PolarHBondContact O-N 2.96Å; Q358-R360 VanDerWaalsContact C-N 3.32Å; Q358-R360 PolarHBondContact O-N 2.77Å; Q358-E361 PolarHBondContact O-N 3.13Å; Q358-N362 VanDerWaalsContact O-CG 3.28Å; Q358-N362 PolarHBondContact O-N 3.38Å; Q358-N362 PolarHBondContact O-ND2 3.33Å
359E93.8Very high93Very high104 Ų104101.3 Ų101.349%0.48649%0.49SS..Hα-helixtrans-68.9-28.5178.4-67.9-55.5153.200113.3K355 V356 L357 N362 Y363K355-E359 PolarHBondContact O-N 3.2Å; V356-E359 PolarHBondContact O-N 2.63Å; L357-E359 PolarHBondContact O-N 3.2Å; E359-N362 PolarHBondContact O-N 3.25Å; E359-N362 PolarHBondContact OE2-ND2 3.18Å; E359-Y363 VanDerWaalsContact O-CB 3.28Å; E359-Y363 WeakPolarHBondContact O-CB 3.36Å; E359-Y363 PolarHBondContact O-N 2.88Å
360R91.5Very high92.7Very high124 Ų124102.9 Ų102.947%0.46851%0.509SS..Hα-helixtrans-66.5-41.3172.1-78.8172.6-178-174.82.1111.8V356 L357 Q358 Y363 Q364V356-R360 HydrophobicContact CG1-CG 4.36Å; V356-R360 WeakPolarHBondContact O-CB 3.43Å; V356-R360 WeakPolarHBondContact O-CG 3.34Å; V356-R360 PolarHBondContact O-N 2.82Å; L357-R360 WeakPolarHBondContact O-CB 3.49Å; L357-R360 PolarHBondContact O-N 2.81Å; Q358-R360 VanDerWaalsContact C-N 3.32Å; Q358-R360 PolarHBondContact O-N 2.77Å; R360-Y363 PolarHBondContact O-N 2.92Å; R360-Q364 WeakPolarHBondContact O-CB 3.46Å; R360-Q364 PolarHBondContact O-N 2.83Å
361E93.4Very high92.5Very high124 Ų124106 Ų10658%0.57952%0.52SS*.Hα-helixtrans-63.8-45.2174.9-70.9179.1-177.200111L357 Q358 Y363 Q364 Q365L357-E361 PolarHBondContact O-N 2.81Å; Q358-E361 PolarHBondContact O-N 3.13Å; E361-Y363 VanDerWaalsContact C-N 3.35Å; E361-Y363 PolarHBondContact O-N 3.23Å; E361-Q364 PolarHBondContact O-N 2.92Å; E361-Q365 WeakPolarHBondContact O-CG 3.26Å; E361-Q365 PolarHBondContact O-N 3Å
362N92.1Very high92.1Very high67 Ų67102.6 Ų102.636%0.35851%0.513SS..Hα-helixtrans-57.6-47.1174-66.8-19000111.6Q358 E359 Q364 Q365 S366Q358-N362 VanDerWaalsContact O-CG 3.28Å; Q358-N362 PolarHBondContact O-N 3.38Å; Q358-N362 PolarHBondContact O-ND2 3.33Å; E359-N362 PolarHBondContact O-N 3.25Å; E359-N362 PolarHBondContact OE2-ND2 3.18Å; N362-Q364 PolarHBondContact O-N 3.5Å; N362-Q365 PolarHBondContact O-N 3.06Å; N362-S366 WeakPolarHBondContact O-CB 3.36Å; N362-S366 PolarHBondContact O-N 2.94Å; N362-S366 PolarHBondContact O-OG 3.1Å
363Y90.3Very high91.7Very high83 Ų83108.1 Ų108.133%0.32553%0.533SS..Hα-helixtrans-59.9-46.9176.8178.7-98.4000111.1E359 R360 E361 Q365 S366 S367 S374 P478E359-Y363 VanDerWaalsContact O-CB 3.28Å; E359-Y363 WeakPolarHBondContact O-CB 3.36Å; E359-Y363 PolarHBondContact O-N 2.88Å; R360-Y363 PolarHBondContact O-N 2.92Å; E361-Y363 VanDerWaalsContact C-N 3.35Å; E361-Y363 PolarHBondContact O-N 3.23Å; Y363-Q365 PolarHBondContact O-N 2.82Å; Y363-S366 WeakPolarHBondContact CA-OG 3.4Å; Y363-S366 PolarHBondContact O-N 2.86Å; Y363-S366 PolarHBondContact O-OG 2.78Å; Y363-S367 WeakPolarHBondContact O-CB 3.32Å; Y363-S367 PolarHBondContact O-N 2.99Å; Y363-S374 VanDerWaalsContact OH-CB 3.26Å; Y363-S374 WeakPolarHBondContact OH-CB 3.32Å; Y363-S374 PolarHBondContact OH-OG 3.04Å; Y363-P478 HydrophobicContact CE1-CG 4.35Å
364Q89.9Confident91.4Very high115 Ų115106.5 Ų106.554%0.53753%0.534SS..Hα-helixtrans-60.9-43.5179.2-173.463.632.900112R360 E361 N362 S367R360-Q364 WeakPolarHBondContact O-CB 3.46Å; R360-Q364 PolarHBondContact O-N 2.83Å; E361-Q364 PolarHBondContact O-N 2.92Å; N362-Q364 PolarHBondContact O-N 3.5Å; Q364-S367 PolarHBondContact O-N 3.06Å; Q364-S367 PolarHBondContact O-OG 2.54Å
365Q91.3Very high91Very high131 Ų131102.9 Ų102.961%0.61254%0.537SS*.Hα-helixtrans-62.9-44.9175.2-69.4175.917.400111.4E361 N362 Y363 S367 Q368E361-Q365 WeakPolarHBondContact O-CG 3.26Å; E361-Q365 PolarHBondContact O-N 3Å; N362-Q365 PolarHBondContact O-N 3.06Å; Y363-Q365 PolarHBondContact O-N 2.82Å; Q365-S367 VanDerWaalsContact C-N 3.26Å; Q365-S367 PolarHBondContact O-N 2.83Å; Q365-Q368 PolarHBondContact O-N 3.3Å
366S90.2Very high90.7Very high57 Ų57102.4 Ų102.440%0.39954%0.543SS..Hα-helixtrans-65.2-30.4179.175.30000112.9N362 Y363 Q368 S369 A372N362-S366 WeakPolarHBondContact O-CB 3.36Å; N362-S366 PolarHBondContact O-N 2.94Å; N362-S366 PolarHBondContact O-OG 3.1Å; Y363-S366 WeakPolarHBondContact CA-OG 3.4Å; Y363-S366 PolarHBondContact O-N 2.86Å; Y363-S366 PolarHBondContact O-OG 2.78Å; S366-Q368 PolarHBondContact O-N 3.08Å; S366-S369 VanDerWaalsContact O-CB 3.31Å; S366-S369 WeakPolarHBondContact O-CB 3.4Å; S366-S369 PolarHBondContact O-N 3.22Å; S366-S369 VanDerWaalsContact O-N 3.09Å; S366-A372 WeakPolarHBondContact O-CB 3.19Å
367S88.2Confident90.4Very high48 Ų48101 Ų10134%0.33654%0.536SS..Hα-helixtrans-66.8-18.2-179.477.20000113.7Y363 Q364 Q365 S369Y363-S367 WeakPolarHBondContact O-CB 3.32Å; Y363-S367 PolarHBondContact O-N 2.99Å; Q364-S367 PolarHBondContact O-N 3.06Å; Q364-S367 PolarHBondContact O-OG 2.54Å; Q365-S367 VanDerWaalsContact C-N 3.26Å; Q365-S367 PolarHBondContact O-N 2.83Å; S367-S369 VanDerWaalsContact C-N 3.3Å
368Q89.4Confident90Very high159 Ų159101.9 Ų101.974%0.74355%0.549SS*.THydrogen-bonded Turntrans-78.8-11.7175.3-60.9179.1-0.900113.2Q365 S366Q365-Q368 PolarHBondContact O-N 3.3Å; S366-Q368 PolarHBondContact O-N 3.08Å
369S91.2Very high89.8Confident60 Ų6098.3 Ų98.342%0.4253%0.532SS..  trans-76.2126.2178.2176.70000111.5S366 S367 K371 A372S366-S369 VanDerWaalsContact O-CB 3.31Å; S366-S369 WeakPolarHBondContact O-CB 3.4Å; S366-S369 PolarHBondContact O-N 3.22Å; S366-S369 VanDerWaalsContact O-N 3.09Å; S367-S369 VanDerWaalsContact C-N 3.3Å; S369-K371 PolarHBondContact O-N 2.82Å; S369-K371 VanDerWaalsContact O-N 3.16Å; S369-K371 PolarHBondContact OG-N 2.84Å; S369-A372 PolarHBondContact O-N 2.9Å; S369-A372 VanDerWaalsContact O-N 3.14Å
370S86.7Confident89.7Confident126 Ų12694.9 Ų94.988%0.88153%0.526SS*.THydrogen-bonded Turntrans-66.1-15.4177.459.50000114.6
371K91Very high89.8Confident190 Ų19089.5 Ų89.583%0.82651%0.506SS*.THydrogen-bonded Turntrans-97-14.7177-63.9-177.4-178.6178.60112.9S369S369-K371 PolarHBondContact O-N 2.82Å; S369-K371 VanDerWaalsContact O-N 3.16Å; S369-K371 PolarHBondContact OG-N 2.84Å
372A87.1Confident90Very high50 Ų5086.9 Ų86.941%0.41350%0.496SS..  trans-76.8146.1-179.300000110.4S366 S369S366-A372 WeakPolarHBondContact O-CB 3.19Å; S369-A372 PolarHBondContact O-N 2.9Å; S369-A372 VanDerWaalsContact O-N 3.14Å
373K88Confident90.2Very high202 Ų20286.4 Ų86.488%0.87849%0.493SS*.  trans-120.1126.5171.5-67.1-175.4179.1-177.30108.4A375K373-A375 PolarHBondContact O-N 2.77Å
374S87.5Confident90.4Very high71 Ų7184.8 Ų84.850%0.49749%0.488SS..PPolyproline II helixtrans-72.8120.1174.4-690000110.1Y363Y363-S374 VanDerWaalsContact OH-CB 3.26Å; Y363-S374 WeakPolarHBondContact OH-CB 3.32Å; Y363-S374 PolarHBondContact OH-OG 3.04Å
375A87.9Confident90.6Very high83 Ų8381.4 Ų81.469%0.68647%0.471SS*.PPolyproline II helixtrans-74.5138.8169.900000109.9K373K373-A375 PolarHBondContact O-N 2.77Å
376V89.3Confident90.7Very high104 Ų10477.6 Ų77.663%0.6346%0.457SS*.PPolyproline II helixtrans-92.6127.3175.8-179.90000108.3S378 T480V376-S378 PolarHBondContact O-N 3Å; V376-T480 HydrophobicContact CG1-CG2 4.5Å; V376-T480 WeakPolarHBondContact CG1-OG1 3.48Å
377P88.5Confident90.8Very high41 Ų4175.8 Ų75.827%0.26644%0.443SS..PPolyproline II helixtrans-65.8124.817626-31.4000109.9I476 P478 T480P377-I476 HydrophobicContact CB-CD1 4.17Å; P377-I476 HydrophobicContact CG-CD1 3.91Å; P377-I476 HydrophobicContact CG-CG1 4.49Å; P377-P478 WeakPolarHBondContact CG-O 3.18Å; P377-T480 HydrophobicContact CG-CG2 3.77Å
378S87.4Confident90.9Very high112 Ų11275.4 Ų75.478%0.78344%0.437SS*.PPolyproline II helixtrans-82136.817255.90000110.2V376V376-S378 PolarHBondContact O-N 3Å
379F91.6Very high90.7Very high13 Ų1372 Ų726%0.05742%0.42CS..  trans-134.8154.7171.161.8-83.5000109.7I381 V400 P474 I476 T480 Q482F379-I381 HydrophobicContact CD2-CG1 3.93Å; F379-I381 HydrophobicContact CE2-CD1 3.73Å; F379-I381 HydrophobicContact CE2-CG1 3.5Å; F379-I381 HydrophobicContact CZ-CD1 4.31Å; F379-I381 HydrophobicContact CZ-CG1 4.5Å; F379-V400 HydrophobicContact CD2-CG1 3.7Å; F379-V400 HydrophobicContact CE2-CG1 4.16Å; F379-V400 HydrophobicContact CE2-CG2 4.42Å; F379-P474 HydrophobicContact CD1-CG 3.9Å; F379-P474 HydrophobicContact CD2-CG 4.06Å; F379-P474 HydrophobicContact CE1-CG 3.66Å; F379-P474 HydrophobicContact CE2-CG 3.78Å; F379-P474 HydrophobicContact CG-CG 4.1Å; F379-P474 HydrophobicContact CZ-CG 3.59Å; F379-I476 HydrophobicContact CD1-CD1 4.05Å; F379-T480 HydrophobicContact CD1-CG2 3.91Å; F379-T480 HydrophobicContact CE1-CG2 3.58Å; F379-Q482 HydrophobicContact CD1-CG 4.39Å; F379-Q482 HydrophobicContact CE1-CB 4.27Å; F379-Q482 HydrophobicContact CE1-CG 3.61Å; F379-Q482 HydrophobicContact CE2-CB 4.4Å; F379-Q482 HydrophobicContact CE2-CG 4.35Å; F379-Q482 HydrophobicContact CZ-CB 3.76Å; F379-Q482 HydrophobicContact CZ-CG 3.6Å; F379-Q482 PolarHBondContact O-NE2 2.64Å; F379-Q482 PolarHBondContact O-OE1 3.3Å
380G90.6Very high90.3Very high33 Ų3374.4 Ų74.434%0.3443%0.428SS..  trans-87.1134.8174.200000111.1Y310Y310-G380 PolarHBondContact OH-O 3.12Å
381I95.5Very high90.1Very high11 Ų1170 Ų706%0.05639%0.394CS..EExtended strand (participates in β ladder)trans-108.3122.9166.2-57.7169.9000106.1F379 D383 L398 E399 V400 V472 Q482 R484F379-I381 HydrophobicContact CD2-CG1 3.93Å; F379-I381 HydrophobicContact CE2-CD1 3.73Å; F379-I381 HydrophobicContact CE2-CG1 3.5Å; F379-I381 HydrophobicContact CZ-CD1 4.31Å; F379-I381 HydrophobicContact CZ-CG1 4.5Å; I381-D383 HydrophobicContact CG2-CB 4.25Å; I381-L398 HydrophobicContact CG2-CD2 4.25Å; I381-E399 WeakPolarHBondContact CA-O 3.34Å; I381-V400 HydrophobicContact CG1-CG2 4.12Å; I381-V472 HydrophobicContact CD1-CB 3.76Å; I381-V472 HydrophobicContact CD1-CG1 4.27Å; I381-V472 HydrophobicContact CD1-CG2 3.94Å; I381-Q482 HydrophobicContact CD1-CB 3.77Å; I381-R484 HydrophobicContact CD1-CG 4.12Å
382N96Very high90.1Very high69 Ų6961 Ų6137%0.36936%0.356SS..EExtended strand (participates in β ladder)trans-91102.9168.117744.2000107.3Y310 E399Y310-N382 HydrophobicContact CD2-CB 4.25Å; Y310-N382 HydrophobicContact CE1-CB 4.24Å; Y310-N382 HydrophobicContact CE2-CB 3.57Å; Y310-N382 PolarHBondContact OH-N 3.33Å; N382-E399 HydrophobicContact CB-CB 4.17Å; N382-E399 PolarHBondContact N-O 2.69Å; N382-E399 PolarHBondContact ND2-OE2 3.13Å; N382-E399 PolarHBondContact O-N 3.2Å
383D96.2Very high90.3Very high56 Ų5658.6 Ų58.630%0.29934%0.336SS..EExtended strand (participates in β ladder)trans-111.1142.7-17755.1-35.9000112.6I381 I397 L398 Y486I381-D383 HydrophobicContact CG2-CB 4.25Å; D383-I397 CarbonylContact C-O 3.59Å; D383-I397 VanDerWaalsContact CA-O 3.27Å; D383-I397 WeakPolarHBondContact CA-O 3.43Å; D383-L398 HydrophobicContact CB-CD2 3.94Å; D383-Y486 HydrophobicContact CB-CE1 4.3Å; D383-Y486 WeakPolarHBondContact CB-OH 3.5Å; D383-Y486 WeakPolarHBondContact OD2-CE1 3.31Å; D383-Y486 PolarHBondContact OD2-OH 3.4Å; D383-Y486 VanDerWaalsContact OD2-OH 3.08Å
384K94.8Very high90.7Very high49 Ų4949.5 Ų49.521%0.21330%0.296CS..EExtended strand (participates in β ladder)trans-137.7125.6175.1-178.3178.9179.3-168.60109S212 D262 T386 L396 I397S212-K384 PolarHBondContact O-NZ 3.44Å; D262-K384 IonicContact OD2-NZ 3.59Å; D262-K384 PolarHBondContact OD2-NZ 3.44Å; K384-T386 HydrophobicContact CD-CG2 4.23Å; K384-T386 HydrophobicContact CG-CG2 3.69Å; K384-L396 CarbonylContact O-C 3.56Å; K384-L396 WeakPolarHBondContact O-CA 3.39Å; K384-I397 HydrophobicContact CB-CB 4.29Å; K384-I397 HydrophobicContact CD-CD1 4.2Å; K384-I397 PolarHBondContact N-O 2.9Å; K384-I397 PolarHBondContact O-N 3.5Å
385F95.4Very high91Very high44 Ų4446.6 Ų46.619%0.19328%0.276CS..EExtended strand (participates in β ladder)trans-124.396.7177.5-171.2-116.4000109.3Y394 L396 I458 L468 Y486 I488F385-Y394 HydrophobicContact CD1-CD1 4.01Å; F385-Y394 HydrophobicContact CD1-CE1 4.31Å; F385-Y394 HydrophobicContact CD2-CD1 4.45Å; F385-Y394 AromaticContact CE1-CD1 3.49Å; F385-Y394 HydrophobicContact CE1-CD1 3.49Å; F385-Y394 VanDerWaalsContact CE1-CD1 3.49Å; F385-Y394 AromaticContact CE1-CE1 3.73Å; F385-Y394 HydrophobicContact CE1-CE1 3.73Å; F385-Y394 HydrophobicContact CE1-CG 4.01Å; F385-Y394 VanDerWaalsContact CE2-CB 3.5Å; F385-Y394 AromaticContact CE2-CD1 3.98Å; F385-Y394 HydrophobicContact CE2-CD1 3.98Å; F385-Y394 AromaticContact CE2-CG 3.91Å; F385-Y394 HydrophobicContact CE2-CG 3.91Å; F385-Y394 HydrophobicContact CG-CD1 4.46Å; F385-Y394 AromaticContact CZ-CD1 3.46Å; F385-Y394 HydrophobicContact CZ-CD1 3.46Å; F385-Y394 VanDerWaalsContact CZ-CD1 3.46Å; F385-Y394 HydrophobicContact CZ-CD2 4.17Å; F385-Y394 HydrophobicContact CZ-CE1 4.09Å; F385-Y394 AromaticContact CZ-CG 3.49Å; F385-Y394 HydrophobicContact CZ-CG 3.49Å; F385-Y394 VanDerWaalsContact CZ-CG 3.49Å; F385-L396 HydrophobicContact CB-CD1 4.28Å; F385-L396 HydrophobicContact CD2-CB 3.87Å; F385-L396 HydrophobicContact CD2-CD1 3.99Å; F385-L396 HydrophobicContact CD2-CG 4.43Å; F385-L396 HydrophobicContact CE2-CB 4.29Å; F385-I458 HydrophobicContact CE2-CD1 4.22Å; F385-L468 HydrophobicContact CE2-CD2 4.15Å; F385-L468 HydrophobicContact CZ-CD2 4.45Å; F385-Y486 HydrophobicContact CB-CD1 3.64Å; F385-Y486 HydrophobicContact CB-CE1 4.05Å; F385-Y486 HydrophobicContact CB-CG 4.34Å; F385-Y486 HydrophobicContact CD1-CD1 4.36Å; F385-Y486 HydrophobicContact CD1-CG 4.42Å; F385-Y486 HydrophobicContact CD2-CG 4.49Å; F385-Y486 AromaticContact CG-CD1 3.95Å; F385-Y486 HydrophobicContact CG-CD1 3.95Å; F385-Y486 HydrophobicContact CG-CG 4.17Å; F385-I488 HydrophobicContact CE1-CD1 4.02Å; F385-I488 HydrophobicContact CZ-CD1 3.56Å
386T92.3Very high91.3Very high51 Ų5142.6 Ų42.631%0.31324%0.243SC..EExtended strand (participates in β ladder)trans-127.5136.5-170.448.30000112K384 Y394 S395K384-T386 HydrophobicContact CD-CG2 4.23Å; K384-T386 HydrophobicContact CG-CG2 3.69Å; T386-Y394 CarbonylContact O-C 3.53Å; T386-Y394 WeakPolarHBondContact O-CA 3.36Å; T386-S395 PolarHBondContact N-O 2.99Å; T386-S395 VanDerWaalsContact N-O 3.1Å; T386-S395 PolarHBondContact O-N 2.99Å
387L92.8Very high91.6Very high19 Ų1938.3 Ų38.310%0.09922%0.216CC..EExtended strand (participates in β ladder)trans-74.1123.7172.9-17866.3000109.7Y394 S492 L493 Q495 T548L387-Y394 HydrophobicContact CB-CD1 4.11Å; L387-Y394 HydrophobicContact CB-CE1 3.9Å; L387-Y394 HydrophobicContact CD1-CD2 4.07Å; L387-Y394 HydrophobicContact CD1-CE1 4.4Å; L387-Y394 HydrophobicContact CD1-CE2 3.95Å; L387-Y394 HydrophobicContact CD1-CG 4.36Å; L387-S492 WeakPolarHBondContact CD2-O 3.27Å; L387-L493 HydrophobicContact CD1-CD2 4.35Å; L387-Q495 HydrophobicContact CD2-CG 4.47Å; L387-T548 HydrophobicContact CD2-CG2 3.72Å; L387-T548 HydrophobicContact CG-CG2 4.36Å
388N89.3Confident92Very high40 Ų4036.3 Ų36.321%0.21420%0.204CC..EExtended strand (participates in β ladder)trans-88125.5172.2-169.2-15.4000109.7D390 D391 A392 S393N388-D390 PolarHBondContact OD1-N 3.35Å; N388-D390 VanDerWaalsContact OD1-N 3.13Å; N388-D391 WeakPolarHBondContact CB-OD1 3.46Å; N388-A392 WeakPolarHBondContact O-CA 3.32Å; N388-A392 PolarHBondContact O-N 3.19Å; N388-S393 WeakPolarHBondContact CB-O 3.32Å; N388-S393 PolarHBondContact N-O 2.6Å
389K86.2Confident92.4Very high89 Ų8931 Ų3139%0.38717%0.166SC..THydrogen-bonded Turntrans-68.8-35.7-178.4-174.5173.3-177.7170.80112T548K389-T548 HydrophobicContact CB-CG2 4.42Å; K389-T548 HydrophobicContact CG-CG2 4.2Å
390D82.8Confident92.6Very high109 Ų10930.4 Ų30.458%0.58316%0.164SC*.THydrogen-bonded Turntrans-73-33-169.2-64.7-13.5000113.5K237 N388K237-D390 WeakPolarHBondContact CE-OD2 3.38Å; N388-D390 PolarHBondContact OD1-N 3.35Å; N388-D390 VanDerWaalsContact OD1-N 3.13Å
391D82.9Confident92.7Very high33 Ų3332.4 Ų32.418%0.17616%0.164CC..THydrogen-bonded Turntrans-119.64.7-17765.914000114N388 S393 K457N388-D391 WeakPolarHBondContact CB-OD1 3.46Å; D391-S393 PolarHBondContact O-N 2.78Å; D391-S393 WeakPolarHBondContact OD1-CB 3.37Å; D391-S393 PolarHBondContact OD1-N 2.96Å; D391-S393 PolarHBondContact OD1-OG 3.24Å; D391-S393 PolarHBondContact OD2-OG 2.94Å; D391-K457 IonicContact OD2-NZ 3.53Å; D391-K457 PolarHBondContact OD2-NZ 3.29Å
392A89.6Confident92.5Very high2 Ų233.8 Ų33.82%0.01717%0.173CC..THydrogen-bonded Turntrans47.346.6-178.500000112.6N388 F549 R669N388-A392 WeakPolarHBondContact O-CA 3.32Å; N388-A392 PolarHBondContact O-N 3.19Å; A392-F549 HydrophobicContact CB-CB 3.81Å; A392-F549 HydrophobicContact CB-CD2 3.77Å; A392-F549 HydrophobicContact CB-CG 4.25Å; A392-R669 PolarHBondContact O-NH1 3.26Å; A392-R669 PolarHBondContact O-NH2 3.28Å
393S92.5Very high92.4Very high0 Ų031.2 Ų31.20%016%0.162CC..EExtended strand (participates in β ladder)trans-131.1151.3175.776.60000110.9N388 D391N388-S393 WeakPolarHBondContact CB-O 3.32Å; N388-S393 PolarHBondContact N-O 2.6Å; D391-S393 PolarHBondContact O-N 2.78Å; D391-S393 WeakPolarHBondContact OD1-CB 3.37Å; D391-S393 PolarHBondContact OD1-N 2.96Å; D391-S393 PolarHBondContact OD1-OG 3.24Å; D391-S393 PolarHBondContact OD2-OG 2.94Å
394Y95.1Very high92.4Very high10 Ų1028.6 Ų28.64%0.03915%0.148CC..EExtended strand (participates in β ladder)trans-81.8137.3170.8-72.7-92.7000110.3F385 T386 L387 K457 I458 S492F385-Y394 HydrophobicContact CD1-CD1 4.01Å; F385-Y394 HydrophobicContact CD1-CE1 4.31Å; F385-Y394 HydrophobicContact CD2-CD1 4.45Å; F385-Y394 AromaticContact CE1-CD1 3.49Å; F385-Y394 HydrophobicContact CE1-CD1 3.49Å; F385-Y394 VanDerWaalsContact CE1-CD1 3.49Å; F385-Y394 AromaticContact CE1-CE1 3.73Å; F385-Y394 HydrophobicContact CE1-CE1 3.73Å; F385-Y394 HydrophobicContact CE1-CG 4.01Å; F385-Y394 VanDerWaalsContact CE2-CB 3.5Å; F385-Y394 AromaticContact CE2-CD1 3.98Å; F385-Y394 HydrophobicContact CE2-CD1 3.98Å; F385-Y394 AromaticContact CE2-CG 3.91Å; F385-Y394 HydrophobicContact CE2-CG 3.91Å; F385-Y394 HydrophobicContact CG-CD1 4.46Å; F385-Y394 AromaticContact CZ-CD1 3.46Å; F385-Y394 HydrophobicContact CZ-CD1 3.46Å; F385-Y394 VanDerWaalsContact CZ-CD1 3.46Å; F385-Y394 HydrophobicContact CZ-CD2 4.17Å; F385-Y394 HydrophobicContact CZ-CE1 4.09Å; F385-Y394 AromaticContact CZ-CG 3.49Å; F385-Y394 HydrophobicContact CZ-CG 3.49Å; F385-Y394 VanDerWaalsContact CZ-CG 3.49Å; T386-Y394 CarbonylContact O-C 3.53Å; T386-Y394 WeakPolarHBondContact O-CA 3.36Å; L387-Y394 HydrophobicContact CB-CD1 4.11Å; L387-Y394 HydrophobicContact CB-CE1 3.9Å; L387-Y394 HydrophobicContact CD1-CD2 4.07Å; L387-Y394 HydrophobicContact CD1-CE1 4.4Å; L387-Y394 HydrophobicContact CD1-CE2 3.95Å; L387-Y394 HydrophobicContact CD1-CG 4.36Å; Y394-K457 CarbonylContact O-C 3.55Å; Y394-K457 WeakPolarHBondContact O-CA 3.29Å; Y394-I458 PolarHBondContact N-O 3Å; Y394-I458 PolarHBondContact O-N 3.06Å; Y394-S492 VanDerWaalsContact OH-CA 3.3Å; Y394-S492 WeakPolarHBondContact OH-CA 3.26Å; Y394-S492 VanDerWaalsContact OH-CB 3.26Å; Y394-S492 WeakPolarHBondContact OH-CB 3.17Å; Y394-S492 PolarHBondContact OH-O 2.78Å
395S93.6Very high92.4Very high10 Ų1028.1 Ų28.17%0.0715%0.147CC..EExtended strand (participates in β ladder)trans-101.8113.1168-57.30000108.4T386 L456T386-S395 PolarHBondContact N-O 2.99Å; T386-S395 VanDerWaalsContact N-O 3.1Å; T386-S395 PolarHBondContact O-N 2.99Å; S395-L456 WeakPolarHBondContact CA-O 3.44Å
396L96.1Very high92.4Very high0 Ų028 Ų280%015%0.149CC..EExtended strand (participates in β ladder)trans-95.9113.1170.8176.858.3000108.8K384 F385 L398 I409 E455 L456 I458 L468 A470 Y486K384-L396 CarbonylContact O-C 3.56Å; K384-L396 WeakPolarHBondContact O-CA 3.39Å; F385-L396 HydrophobicContact CB-CD1 4.28Å; F385-L396 HydrophobicContact CD2-CB 3.87Å; F385-L396 HydrophobicContact CD2-CD1 3.99Å; F385-L396 HydrophobicContact CD2-CG 4.43Å; F385-L396 HydrophobicContact CE2-CB 4.29Å; L396-L398 HydrophobicContact CD1-CD2 4.06Å; L396-L398 HydrophobicContact CD1-CG 4.36Å; L396-L398 HydrophobicContact CD2-CD1 4.46Å; L396-L398 HydrophobicContact CG-CD2 4.42Å; L396-L398 HydrophobicContact CG-CG 4.23Å; L396-I409 HydrophobicContact CD2-CD1 4.35Å; L396-E455 WeakPolarHBondContact O-CA 3.28Å; L396-L456 HydrophobicContact CB-CB 4.34Å; L396-L456 HydrophobicContact CD2-CD1 4.42Å; L396-L456 PolarHBondContact N-O 2.97Å; L396-L456 PolarHBondContact O-N 2.75Å; L396-I458 HydrophobicContact CB-CD1 3.98Å; L396-I458 HydrophobicContact CD2-CD1 4.09Å; L396-L468 HydrophobicContact CD2-CD2 4.19Å; L396-A470 HydrophobicContact CD2-CB 4.42Å; L396-Y486 HydrophobicContact CD1-CD1 4.41Å; L396-Y486 HydrophobicContact CD1-CD2 4.2Å; L396-Y486 HydrophobicContact CD1-CE1 3.86Å; L396-Y486 HydrophobicContact CD1-CE2 3.61Å; L396-Y486 VanDerWaalsContact CD1-CZ 3.42Å; L396-Y486 HydrophobicContact CD2-CD2 4.3Å; L396-Y486 HydrophobicContact CD2-CE2 3.94Å; L396-Y486 HydrophobicContact CG-CE2 4.45Å
397I95.4Very high92.7Very high13 Ų1325.5 Ų25.57%0.06713%0.134CC..EExtended strand (participates in β ladder)trans-108.6130.4175.3-61.8156.1000107.9D383 K384 R453 L454 E455D383-I397 CarbonylContact C-O 3.59Å; D383-I397 VanDerWaalsContact CA-O 3.27Å; D383-I397 WeakPolarHBondContact CA-O 3.43Å; K384-I397 HydrophobicContact CB-CB 4.29Å; K384-I397 HydrophobicContact CD-CD1 4.2Å; K384-I397 PolarHBondContact N-O 2.9Å; K384-I397 PolarHBondContact O-N 3.5Å; I397-R453 VanDerWaalsContact CD1-NH2 3.29Å; I397-R453 HydrophobicContact CG2-CG 4.05Å; I397-L454 WeakPolarHBondContact CA-O 3.48Å; I397-E455 HydrophobicContact CG1-CB 4.26Å; I397-E455 HydrophobicContact CG1-CG 3.89Å
398L96.5Very high92.9Very high0 Ų027.3 Ų27.30%014%0.143CC..EExtended strand (participates in β ladder)trans-125.2122.2177.2-60.6169.8000108.5I381 D383 L396 V407 R453 L454 A470 V472 Y486I381-L398 HydrophobicContact CG2-CD2 4.25Å; D383-L398 HydrophobicContact CB-CD2 3.94Å; L396-L398 HydrophobicContact CD1-CD2 4.06Å; L396-L398 HydrophobicContact CD1-CG 4.36Å; L396-L398 HydrophobicContact CD2-CD1 4.46Å; L396-L398 HydrophobicContact CG-CD2 4.42Å; L396-L398 HydrophobicContact CG-CG 4.23Å; L398-V407 HydrophobicContact CD1-CG1 3.71Å; L398-V407 HydrophobicContact CD1-CG2 4.33Å; L398-R453 CarbonylContact O-C 3.54Å; L398-R453 WeakPolarHBondContact O-CA 3.47Å; L398-L454 PolarHBondContact N-O 2.96Å; L398-L454 PolarHBondContact O-N 2.88Å; L398-A470 HydrophobicContact CD1-CB 4.11Å; L398-V472 HydrophobicContact CD1-CG2 3.95Å; L398-V472 HydrophobicContact CD2-CG2 4.42Å; L398-Y486 WeakPolarHBondContact CD2-OH 3.47Å
399E95.9Very high93.3Very high0 Ų025.4 Ų25.40%013%0.133CC..EExtended strand (participates in β ladder)trans-129.5133.1-179.4-174.9-179.3-148.200111.4S288 Y310 I381 N382 T452 R453S288-E399 WeakPolarHBondContact CB-OE2 3.29Å; S288-E399 PolarHBondContact N-OE1 3.09Å; S288-E399 PolarHBondContact OG-OE1 3.4Å; S288-E399 PolarHBondContact OG-OE2 2.93Å; Y310-E399 WeakPolarHBondContact CB-OE1 3.47Å; Y310-E399 HydrophobicContact CD1-CG 3.58Å; Y310-E399 HydrophobicContact CE1-CG 3.93Å; Y310-E399 HydrophobicContact CG-CG 4.24Å; I381-E399 WeakPolarHBondContact CA-O 3.34Å; N382-E399 HydrophobicContact CB-CB 4.17Å; N382-E399 PolarHBondContact N-O 2.69Å; N382-E399 PolarHBondContact ND2-OE2 3.13Å; N382-E399 PolarHBondContact O-N 3.2Å; E399-T452 WeakPolarHBondContact CA-O 3.38Å; E399-R453 HydrophobicContact CB-CB 4.39Å; E399-R453 HydrophobicContact CB-CG 4.33Å; E399-R453 HydrophobicContact CG-CB 4.2Å
400V95.4Very high93.8Very high0 Ų022.2 Ų22.20%012%0.119CC..EExtended strand (participates in β ladder)trans-132.2145.9-177.1-172.40000109.7F379 I381 T402 I404 T452 V472 P474F379-V400 HydrophobicContact CD2-CG1 3.7Å; F379-V400 HydrophobicContact CE2-CG1 4.16Å; F379-V400 HydrophobicContact CE2-CG2 4.42Å; I381-V400 HydrophobicContact CG1-CG2 4.12Å; V400-T402 PolarHBondContact O-N 2.64Å; V400-T402 VanDerWaalsContact O-N 3.16Å; V400-I404 HydrophobicContact CB-CG1 4.34Å; V400-I404 HydrophobicContact CG2-CD1 4.34Å; V400-I404 HydrophobicContact CG2-CG1 4.22Å; V400-T452 PolarHBondContact N-O 3.01Å; V400-T452 WeakPolarHBondContact O-CB 3.46Å; V400-V472 HydrophobicContact CG2-CG1 3.82Å; V400-P474 HydrophobicContact CG1-CB 4.19Å
401Q92.1Very high94.4Very high76 Ų7617 Ų1736%0.3559%0.091SC..SBendtrans-59.7-26.7-179.475.2-174.8-5.500114.1V15V15-Q401 HydrophobicContact CG2-CB 3.41Å; V15-Q401 VanDerWaalsContact CG2-CB 3.41Å; V15-Q401 HydrophobicContact CG2-CG 4.26Å
402T92.4Very high95Very high39 Ų3917.4 Ų17.424%0.2399%0.094CC..SBendtrans-115.5154.5179.356.80000109.5V400 I404 P474 I476V400-T402 PolarHBondContact O-N 2.64Å; V400-T402 VanDerWaalsContact O-N 3.16Å; T402-I404 PolarHBondContact O-N 2.99Å; T402-P474 VanDerWaalsContact OG1-CB 3.24Å; T402-P474 WeakPolarHBondContact OG1-CB 3.43Å; T402-I476 HydrophobicContact CG2-CG2 3.73Å
403A93.6Very high95.2Very high16 Ų1617.7 Ų17.713%0.13210%0.095CC..  trans-51.2134.317600000112.2T451 R475A403-T451 CarbonylContact C-O 3.13Å; A403-T451 WeakPolarHBondContact CA-O 3.36Å; A403-R475 WeakPolarHBondContact O-CB 3.43Å; A403-R475 WeakPolarHBondContact O-CG 3.4Å; A403-R475 PolarHBondContact O-N 2.83Å
404I95.3Very high95.2Very high0 Ų019.8 Ų19.80%011%0.109CC..EExtended strand (participates in β ladder)trans-75.7135.7177-58.6173.1000108.5V400 T402 V407 C447 T451 L454V400-I404 HydrophobicContact CB-CG1 4.34Å; V400-I404 HydrophobicContact CG2-CD1 4.34Å; V400-I404 HydrophobicContact CG2-CG1 4.22Å; T402-I404 PolarHBondContact O-N 2.99Å; I404-V407 HydrophobicContact CG2-CG2 3.69Å; I404-C447 HydrophobicContact CB-CB 4.24Å; I404-C447 HydrophobicContact CG2-CB 4.38Å; I404-C447 WeakPolarHBondContact O-CB 3.47Å; I404-T451 PolarHBondContact N-O 2.74Å; I404-L454 HydrophobicContact CD1-CB 4.23Å
405D95.3Very high95.1Very high39 Ų3920 Ų2021%0.20911%0.11CC..EExtended strand (participates in β ladder)trans-84.2-58.1171.6-169.133.6000109.1C447 T473 R475 K479D405-C447 PolarHBondContact O-N 2.62Å; D405-C447 VanDerWaalsContact O-N 3.15Å; D405-T473 WeakPolarHBondContact CA-O 3.43Å; D405-T473 HydrophobicContact CB-CG2 4.3Å; D405-T473 VanDerWaalsContact CB-O 3.28Å; D405-T473 WeakPolarHBondContact CB-O 3.49Å; D405-T473 PolarHBondContact N-O 2.96Å; D405-R475 HydrophobicContact CB-CG 3.79Å; D405-R475 IonicContact OD1-NE 3.12Å; D405-K479 IonicContact OD2-NZ 3.52Å; D405-K479 PolarHBondContact OD2-NZ 2.98Å
406N96.1Very high94.9Very high41 Ų4123.2 Ų23.222%0.21913%0.127CC..EExtended strand (participates in β ladder)trans-152155.61776389.6000111.7T444 Y445 T473N406-T444 HydrophobicContact CB-CG2 4.4Å; N406-Y445 CarbonylContact C-O 3.5Å; N406-Y445 WeakPolarHBondContact CA-O 3.42Å; N406-Y445 WeakPolarHBondContact CB-O 3.27Å; N406-T473 PolarHBondContact N-O 2.98Å; N406-T473 PolarHBondContact O-N 3.14Å
407V97.8Very high94.7Very high0 Ų024.3 Ų24.30%013%0.132CC..EExtended strand (participates in β ladder)trans-123.8124.2168.6-177.50000108.6L398 I404 I409 Y445 L454 A470 Y471 V472L398-V407 HydrophobicContact CD1-CG1 3.71Å; L398-V407 HydrophobicContact CD1-CG2 4.33Å; I404-V407 HydrophobicContact CG2-CG2 3.69Å; V407-I409 HydrophobicContact CG1-CD1 3.73Å; V407-I409 HydrophobicContact CG1-CG1 4.41Å; V407-Y445 PolarHBondContact N-O 3.34Å; V407-Y445 PolarHBondContact O-N 2.84Å; V407-L454 HydrophobicContact CB-CD2 3.82Å; V407-L454 HydrophobicContact CG1-CD2 4.4Å; V407-L454 HydrophobicContact CG2-CD2 3.54Å; V407-A470 HydrophobicContact CG1-CB 4.44Å; V407-Y471 VanDerWaalsContact CA-O 3.3Å; V407-Y471 WeakPolarHBondContact CA-O 3.24Å; V407-V472 HydrophobicContact CG1-CG2 4.34Å; V407-V472 HydrophobicContact CG2-CG1 4.39Å; V407-V472 HydrophobicContact CG2-CG2 4.39Å
408L97.6Very high94.3Very high57 Ų5725.6 Ų25.630%0.29814%0.139SC..EExtended strand (participates in β ladder)trans-99.5130170.8-177.7155000109.4Q410 A443 A470 Y471L408-Q410 HydrophobicContact CD2-CB 4.04Å; L408-A443 CarbonylContact C-O 3.59Å; L408-A443 WeakPolarHBondContact CA-O 3.19Å; L408-A470 CarbonylContact O-C 3.57Å; L408-A470 WeakPolarHBondContact O-CA 3.41Å; L408-Y471 HydrophobicContact CD2-CD2 3.63Å; L408-Y471 HydrophobicContact CD2-CE2 4.16Å; L408-Y471 HydrophobicContact CD2-CG 4.37Å; L408-Y471 PolarHBondContact N-O 3.27Å; L408-Y471 PolarHBondContact O-N 2.93Å
409I97.6Very high93.6Very high0 Ų032.5 Ų32.50%018%0.176CC..EExtended strand (participates in β ladder)trans-108.9120.7176.6-55.7-59.4000107.6L396 V407 L441 L442 A443 Y445 L456 L468 Q469 A470L396-I409 HydrophobicContact CD2-CD1 4.35Å; V407-I409 HydrophobicContact CG1-CD1 3.73Å; V407-I409 HydrophobicContact CG1-CG1 4.41Å; I409-L441 HydrophobicContact CG2-CD2 4.4Å; I409-L442 WeakPolarHBondContact O-CA 3.37Å; I409-A443 HydrophobicContact CB-CB 4.41Å; I409-A443 PolarHBondContact N-O 3.06Å; I409-A443 PolarHBondContact O-N 2.95Å; I409-Y445 HydrophobicContact CG1-CD2 4.19Å; I409-Y445 HydrophobicContact CG1-CE2 4.18Å; I409-L456 HydrophobicContact CD1-CD1 3.65Å; I409-L456 HydrophobicContact CG1-CD1 3.82Å; I409-L468 HydrophobicContact CG2-CD1 3.53Å; I409-L468 HydrophobicContact CG2-CG 4.47Å; I409-Q469 WeakPolarHBondContact CA-O 3.49Å; I409-A470 HydrophobicContact CD1-CB 3.76Å
410Q96.1Very high92.9Very high21 Ų2133.6 Ų33.610%0.09818%0.183CC..EExtended strand (participates in β ladder)trans-119.7137174.6177-81.8-32.400108.6L408 N439 L441 L442 Q469 Y471L408-Q410 HydrophobicContact CD2-CB 4.04Å; Q410-N439 VanDerWaalsContact CG-OD1 3.27Å; Q410-N439 WeakPolarHBondContact CG-OD1 3.41Å; Q410-N439 PolarHBondContact NE2-OD1 2.95Å; Q410-L441 WeakPolarHBondContact CA-O 3.39Å; Q410-L442 HydrophobicContact CB-CD2 3.77Å; Q410-L442 HydrophobicContact CG-CD2 3.61Å; Q410-Q469 HydrophobicContact CB-CB 4.42Å; Q410-Q469 PolarHBondContact N-O 3.18Å; Q410-Q469 PolarHBondContact O-N 3.48Å; Q410-Y471 HydrophobicContact CB-CE2 4.3Å
411S96.2Very high92Very high0 Ų041 Ų410%022%0.222CC..EExtended strand (participates in β ladder)trans-134.6136.3177.7-169.90000110.8V413 F440 L441S411-V413 VanDerWaalsContact C-N 3.28Å; S411-V413 WeakPolarHBondContact CB-O 3.31Å; S411-V413 VanDerWaalsContact OG-CG2 3.28Å; S411-V413 WeakPolarHBondContact OG-CG2 3.18Å; S411-V413 PolarHBondContact OG-N 3.33Å; S411-V413 PolarHBondContact OG-O 2.83Å; S411-F440 PolarHBondContact O-N 2.82Å; S411-L441 PolarHBondContact N-O 2.9Å; S411-L441 PolarHBondContact O-N 2.75Å
412D94.6Very high91.3Very high42 Ų4243.9 Ų43.923%0.22523%0.234CC..SBendtrans-88.73.7168.866.97.7000112.6D438 F440 G466 T467D412-D438 WeakPolarHBondContact CA-O 3.48Å; D412-F440 WeakPolarHBondContact O-CD2 3.44Å; D412-F440 VanDerWaalsContact O-CE2 3.25Å; D412-F440 WeakPolarHBondContact O-CE2 3.5Å; D412-G466 VanDerWaalsContact OD1-CA 3.29Å; D412-G466 WeakPolarHBondContact OD1-CA 3.38Å; D412-T467 PolarHBondContact N-O 3.37Å; D412-T467 PolarHBondContact OD1-N 2.9Å; D412-T467 VanDerWaalsContact OD1-O 3.08Å; D412-T467 WeakPolarHBondContact OD2-CB 3.19Å; D412-T467 PolarHBondContact OD2-N 3.05Å; D412-T467 PolarHBondContact OD2-OG1 2.76Å
413V93.6Very high90.8Very high7 Ų743.7 Ų43.74%0.04223%0.231CC..SBendtrans-127.2148.9175.1-75.40000112.1S411 I415 Y465 I488S411-V413 VanDerWaalsContact C-N 3.28Å; S411-V413 WeakPolarHBondContact CB-O 3.31Å; S411-V413 VanDerWaalsContact OG-CG2 3.28Å; S411-V413 WeakPolarHBondContact OG-CG2 3.18Å; S411-V413 PolarHBondContact OG-N 3.33Å; S411-V413 PolarHBondContact OG-O 2.83Å; V413-I415 HydrophobicContact CG2-CG2 4.04Å; V413-I415 PolarHBondContact O-N 3.05Å; V413-Y465 VanDerWaalsContact CG1-O 3.29Å; V413-Y465 WeakPolarHBondContact CG1-O 3.37Å; V413-I488 HydrophobicContact CG2-CB 4.18Å; V413-I488 HydrophobicContact CG2-CG1 3.99Å
414P91.9Very high90.4Very high45 Ų4545.4 Ų45.429%0.29224%0.243SC..  trans-60119.6170.5-19.131.5000110.6F440 I461 Q464P414-F440 HydrophobicContact CG-CD1 3.64Å; P414-F440 HydrophobicContact CG-CE1 4.01Å; P414-F440 HydrophobicContact CG-CG 4.19Å; P414-I461 HydrophobicContact CB-CD1 4.47Å; P414-Q464 VanDerWaalsContact CB-OE1 3.28Å
415I93.2Very high90.1Very high13 Ų1346 Ų467%0.06725%0.247CC..EExtended strand (participates in β ladder)trans-142.3147.9176.452154.3000109.8V413 L417 L441 I458 R459 L468V413-I415 HydrophobicContact CG2-CG2 4.04Å; V413-I415 PolarHBondContact O-N 3.05Å; I415-L417 HydrophobicContact CD1-CD2 4.25Å; I415-L441 HydrophobicContact CD1-CD2 3.48Å; I415-L441 VanDerWaalsContact CD1-CD2 3.48Å; I415-L441 HydrophobicContact CG1-CB 4.27Å; I415-L441 HydrophobicContact CG1-CD2 3.64Å; I415-I458 HydrophobicContact CB-CG2 4.01Å; I415-I458 HydrophobicContact CD1-CG2 3.65Å; I415-I458 HydrophobicContact CG1-CG2 4.46Å; I415-I458 HydrophobicContact CG2-CG2 4.18Å; I415-R459 VanDerWaalsContact CA-O 3.32Å; I415-R459 WeakPolarHBondContact CA-O 3.43Å; I415-R459 WeakPolarHBondContact CB-O 3.4Å; I415-L468 HydrophobicContact CD1-CD1 3.52Å
416D91.1Very high89.9Confident78 Ų7848.5 Ų48.542%0.41726%0.264SS..EExtended strand (participates in β ladder)trans-100.8130.9172.2-48.5-45000109.7I458 R459D416-I458 WeakPolarHBondContact O-CA 3.46Å; D416-R459 HydrophobicContact CB-CB 4.05Å; D416-R459 PolarHBondContact N-O 3.41Å; D416-R459 PolarHBondContact O-N 2.69Å
417L91.3Very high89.8Confident23 Ų2348.5 Ų48.512%0.1227%0.265CS..EExtended strand (participates in β ladder)trans-90.1121.3168.1-61.6-176.5000108.7I415 F429 L441 A443 Y445 K457 I458I415-L417 HydrophobicContact CD1-CD2 4.25Å; L417-F429 HydrophobicContact CB-CE1 4.36Å; L417-F429 HydrophobicContact CB-CZ 4.34Å; L417-F429 HydrophobicContact CD1-CE1 4Å; L417-F429 HydrophobicContact CD1-CZ 4.48Å; L417-F429 HydrophobicContact CG-CE1 4.47Å; L417-L441 HydrophobicContact CD1-CD2 3.74Å; L417-L441 HydrophobicContact CD2-CD2 4.11Å; L417-L441 HydrophobicContact CG-CD2 3.67Å; L417-A443 HydrophobicContact CD1-CB 3.49Å; L417-A443 VanDerWaalsContact CD1-CB 3.49Å; L417-Y445 HydrophobicContact CD1-CE2 3.81Å; L417-Y445 WeakPolarHBondContact CD1-OH 3.39Å; L417-K457 WeakPolarHBondContact CA-O 3.41Å; L417-I458 HydrophobicContact CD2-CD1 4.23Å; L417-I458 HydrophobicContact CD2-CG1 3.79Å; L417-I458 HydrophobicContact CD2-CG2 4.47Å
418L87.4Confident89.6Confident40 Ų4050.9 Ų50.921%0.20928%0.282CS..EExtended strand (participates in β ladder)trans-94.7143.5179.1-52.1174.6000110.1K457L418-K457 HydrophobicContact CB-CB 3.8Å; L418-K457 HydrophobicContact CD1-CB 4.28Å; L418-K457 HydrophobicContact CG-CB 4.39Å; L418-K457 PolarHBondContact N-O 2.93Å
419D80.9Confident89.4Confident146 Ų14653.9 Ų53.978%0.78129%0.293SS*.PPolyproline II helixtrans-65.5142.1173.7-68.8-36.4000111
420V81.6Confident89.2Confident22 Ų2256.8 Ų56.813%0.13331%0.313CS..  trans-123.7115.8178.3178.40000107.1K422 N423 K457V420-K422 HydrophobicContact CG1-CB 4.36Å; V420-K422 PolarHBondContact O-N 2.57Å; V420-K422 VanDerWaalsContact O-N 3.12Å; V420-N423 HydrophobicContact CB-CB 3.99Å; V420-N423 HydrophobicContact CG1-CB 4.36Å; V420-N423 VanDerWaalsContact O-CB 3.23Å; V420-N423 WeakPolarHBondContact O-CB 3.19Å; V420-N423 PolarHBondContact O-N 3.36Å; V420-K457 HydrophobicContact CG2-CB 4.06Å; V420-K457 HydrophobicContact CG2-CD 4.22Å; V420-K457 HydrophobicContact CG2-CG 3.81Å
421D77.3Confident88.8Confident156 Ų15661.1 Ų61.183%0.83435%0.346SS*.THydrogen-bonded Turntrans-59.7-30.3-173.4-56.7-41.6000113.4N423D421-N423 PolarHBondContact O-N 3.3Å
422K76.4Confident88.3Confident136 Ų13663.2 Ų63.259%0.59136%0.359SS*.THydrogen-bonded Turntrans-73.2-14.2176.1-64.2-176-178.9177.30113.3D263 V420D263-K422 IonicContact OD2-NZ 2.75Å; V420-K422 HydrophobicContact CG1-CB 4.36Å; V420-K422 PolarHBondContact O-N 2.57Å; V420-K422 VanDerWaalsContact O-N 3.12Å
423N82Confident87.6Confident35 Ų3566 Ų6619%0.18738%0.375CS..  trans-87.7116.3-176.4-174.31.5000110.5V420 D421 A425 L454 E455V420-N423 HydrophobicContact CB-CB 3.99Å; V420-N423 HydrophobicContact CG1-CB 4.36Å; V420-N423 VanDerWaalsContact O-CB 3.23Å; V420-N423 WeakPolarHBondContact O-CB 3.19Å; V420-N423 PolarHBondContact O-N 3.36Å; D421-N423 PolarHBondContact O-N 3.3Å; N423-A425 WeakPolarHBondContact OD1-CB 3.47Å; N423-A425 PolarHBondContact OD1-N 3.45Å; N423-L454 WeakPolarHBondContact ND2-CD1 3.05Å; N423-L454 VanDerWaalsContact OD1-CD1 3.22Å; N423-L454 WeakPolarHBondContact OD1-CD1 3.19Å; N423-E455 PolarHBondContact ND2-O 3.19Å
424S85.2Confident86.6Confident53 Ų5368.7 Ų68.737%0.37139%0.393SS..  trans-90.1-1.8177.763.20000113.8Q448S424-Q448 WeakPolarHBondContact O-CG 3.41Å; S424-Q448 PolarHBondContact O-NE2 2.96Å
425A89.3Confident85.7Confident12 Ų1276 Ų7610%0.09942%0.424CS..PPolyproline II helixtrans-71.1143.2-178.300000111.8N423 Y445 R446 L454N423-A425 WeakPolarHBondContact OD1-CB 3.47Å; N423-A425 PolarHBondContact OD1-N 3.45Å; A425-Y445 HydrophobicContact CB-CD1 4.07Å; A425-R446 VanDerWaalsContact CA-O 3.29Å; A425-R446 WeakPolarHBondContact CA-O 3.18Å; A425-R446 WeakPolarHBondContact CB-O 3.43Å; A425-L454 HydrophobicContact CB-CD1 3.98Å
426V90.8Very high84.8Confident92 Ų9279.1 Ų79.156%0.55845%0.447SS*.EExtended strand (participates in β ladder)trans-87125.8174.5-178.60000108.8R446V426-R446 PolarHBondContact N-O 3.47Å; V426-R446 PolarHBondContact O-N 2.77Å
427V93.8Very high84Confident41 Ų4180.1 Ų80.125%0.24845%0.452CS..EExtended strand (participates in β ladder)trans-95136.2-179.5-162.90000110.2F429 T444 Y445V427-F429 HydrophobicContact CB-CE2 4.47Å; V427-F429 HydrophobicContact CG1-CD2 4.27Å; V427-F429 HydrophobicContact CG1-CE2 3.74Å; V427-F429 HydrophobicContact CG1-CZ 3.88Å; V427-T444 WeakPolarHBondContact CA-O 2.94Å; V427-Y445 HydrophobicContact CB-CD1 4.46Å; V427-Y445 HydrophobicContact CB-CE1 4.17Å; V427-Y445 HydrophobicContact CG1-CD1 4.45Å; V427-Y445 HydrophobicContact CG1-CD2 4.49Å; V427-Y445 HydrophobicContact CG1-CE1 4Å; V427-Y445 HydrophobicContact CG1-CE2 4.01Å; V427-Y445 HydrophobicContact CG2-CD1 3.6Å; V427-Y445 HydrophobicContact CG2-CE1 3.18Å; V427-Y445 HydrophobicContact CG2-CG 4.49Å
428S93.8Very high83.5Confident49 Ų4984 Ų8434%0.34347%0.473SS..EExtended strand (participates in β ladder)trans-129.3123167.363.10000110A443 T444S428-A443 WeakPolarHBondContact O-CA 3.45Å; S428-T444 PolarHBondContact N-O 3.48Å; S428-T444 PolarHBondContact O-N 3.36Å; S428-T444 PolarHBondContact OG-O 2.67Å
429F93.9Very high83.6Confident121 Ų12183.6 Ų83.653%0.53147%0.471SS..EExtended strand (participates in β ladder)trans-89.4122.7173.7-64.4-85.6000109.6L417 V427 L441 A443L417-F429 HydrophobicContact CB-CE1 4.36Å; L417-F429 HydrophobicContact CB-CZ 4.34Å; L417-F429 HydrophobicContact CD1-CE1 4Å; L417-F429 HydrophobicContact CD1-CZ 4.48Å; L417-F429 HydrophobicContact CG-CE1 4.47Å; V427-F429 HydrophobicContact CB-CE2 4.47Å; V427-F429 HydrophobicContact CG1-CD2 4.27Å; V427-F429 HydrophobicContact CG1-CE2 3.74Å; V427-F429 HydrophobicContact CG1-CZ 3.88Å; F429-L441 HydrophobicContact CD1-CD1 3.87Å; F429-L441 HydrophobicContact CE1-CD1 3.98Å; F429-A443 HydrophobicContact CD1-CB 3.98Å; F429-A443 HydrophobicContact CE1-CB 4.02Å
430S93Very high84.1Confident61 Ų6180.9 Ų80.943%0.42745%0.453SS..PPolyproline II helixtrans-85.3146.6174.3-63.40000109.7C432 L442S430-C432 PolarHBondContact O-N 3.22Å; S430-C432 PolarHBondContact O-SG 3.01Å; S430-L442 PolarHBondContact N-O 2.72Å
431S87.6Confident84.7Confident112 Ų11280.7 Ų80.778%0.78345%0.451SS*.PPolyproline II helixtrans-59.2129.5171.453.40000109.9
432C85.4Confident85.6Confident43 Ų4375.1 Ų75.129%0.29142%0.421SS..  trans-108.2132.8-178.7-62.50000109.7S430 N439 L442S430-C432 PolarHBondContact O-N 3.22Å; S430-C432 PolarHBondContact O-SG 3.01Å; C432-N439 WeakPolarHBondContact CB-O 3.48Å; C432-L442 PolarHBondContact SG-N 3.27Å
433D79.6Confident86.5Confident101 Ų10168.6 Ų68.654%0.5439%0.392SS..  trans-105.693.6171.7-65.9-19.3000108.4E435 S436 N437D433-E435 VanDerWaalsContact C-N 3.25Å; D433-E435 PolarHBondContact O-N 3.34Å; D433-S436 VanDerWaalsContact CB-OG 3.22Å; D433-S436 WeakPolarHBondContact CB-OG 3.23Å; D433-S436 PolarHBondContact O-N 3.44Å; D433-N437 PolarHBondContact O-N 3.35Å
434S72.3Confident87.2Confident63 Ų6368 Ų6844%0.44139%0.39SS..Hα-helixtrans-65.6-28.1-177.953.60000112.8
435E73.3Confident87.7Confident198 Ų19865.7 Ų65.793%0.92537%0.373SS*.Hα-helixtrans-74.4-29.4-179.1-62.8-171.6169.600114D433D433-E435 VanDerWaalsContact C-N 3.25Å; D433-E435 PolarHBondContact O-N 3.34Å
436S74Confident88Confident79 Ų7973.1 Ų73.155%0.55240%0.398SS*.Hα-helixtrans-104.8-35.5-171.362.70000113.7D433D433-S436 VanDerWaalsContact CB-OG 3.22Å; D433-S436 WeakPolarHBondContact CB-OG 3.23Å; D433-S436 PolarHBondContact O-N 3.44Å
437N75.3Confident88Confident100 Ų10069 Ų6954%0.53537%0.374SS..Hα-helixtrans-122.24-168.3-63.8-42.7000114.2D433 N439D433-N437 PolarHBondContact O-N 3.35Å; N437-N439 PolarHBondContact O-N 3.17Å; N437-N439 PolarHBondContact O-ND2 2.89Å
438D81.3Confident87.6Confident104 Ų10472.2 Ų72.256%0.55639%0.386SS*.  trans55.519.5-178.9-148.920.7000113.7D412D412-D438 WeakPolarHBondContact CA-O 3.48Å
439N88.8Confident86.8Confident31 Ų3173 Ų7317%0.16640%0.396CS..  trans-96.1115.1178.9-68.8-44.6000109Q410 C432 N437 L442Q410-N439 VanDerWaalsContact CG-OD1 3.27Å; Q410-N439 WeakPolarHBondContact CG-OD1 3.41Å; Q410-N439 PolarHBondContact NE2-OD1 2.95Å; C432-N439 WeakPolarHBondContact CB-O 3.48Å; N437-N439 PolarHBondContact O-N 3.17Å; N437-N439 PolarHBondContact O-ND2 2.89Å; N439-L442 HydrophobicContact CB-CD1 4.35Å; N439-L442 HydrophobicContact CB-CG 4.23Å
440F91.9Very high86.4Confident90 Ų9073.9 Ų73.940%0.39541%0.406SS..SBendtrans-90.4-25.9173.5-73.5-94.7000112.2S411 D412 P414S411-F440 PolarHBondContact O-N 2.82Å; D412-F440 WeakPolarHBondContact O-CD2 3.44Å; D412-F440 VanDerWaalsContact O-CE2 3.25Å; D412-F440 WeakPolarHBondContact O-CE2 3.5Å; P414-F440 HydrophobicContact CG-CD1 3.64Å; P414-F440 HydrophobicContact CG-CE1 4.01Å; P414-F440 HydrophobicContact CG-CG 4.19Å
441L93.8Very high86.2Confident18 Ų1872 Ų729%0.09439%0.392CS..EExtended strand (participates in β ladder)trans-141.5135.4176-178.973.1000111.3I409 Q410 S411 I415 L417 F429I409-L441 HydrophobicContact CG2-CD2 4.4Å; Q410-L441 WeakPolarHBondContact CA-O 3.39Å; S411-L441 PolarHBondContact N-O 2.9Å; S411-L441 PolarHBondContact O-N 2.75Å; I415-L441 HydrophobicContact CD1-CD2 3.48Å; I415-L441 VanDerWaalsContact CD1-CD2 3.48Å; I415-L441 HydrophobicContact CG1-CB 4.27Å; I415-L441 HydrophobicContact CG1-CD2 3.64Å; L417-L441 HydrophobicContact CD1-CD2 3.74Å; L417-L441 HydrophobicContact CD2-CD2 4.11Å; L417-L441 HydrophobicContact CG-CD2 3.67Å; F429-L441 HydrophobicContact CD1-CD1 3.87Å; F429-L441 HydrophobicContact CE1-CD1 3.98Å
442L95.4Very high86.5Confident38 Ų3867.4 Ų67.420%0.19936%0.359CS..EExtended strand (participates in β ladder)trans-133.9108.5167.1-69.1173000108.9I409 Q410 S430 C432 N439I409-L442 WeakPolarHBondContact O-CA 3.37Å; Q410-L442 HydrophobicContact CB-CD2 3.77Å; Q410-L442 HydrophobicContact CG-CD2 3.61Å; S430-L442 PolarHBondContact N-O 2.72Å; C432-L442 PolarHBondContact SG-N 3.27Å; N439-L442 HydrophobicContact CB-CD1 4.35Å; N439-L442 HydrophobicContact CB-CG 4.23Å
443A95.9Very high86.8Confident0 Ų067.3 Ų67.30%035%0.353CS..EExtended strand (participates in β ladder)trans-123.7141.5177.400000110.6L408 I409 L417 S428 F429 Y445L408-A443 CarbonylContact C-O 3.59Å; L408-A443 WeakPolarHBondContact CA-O 3.19Å; I409-A443 HydrophobicContact CB-CB 4.41Å; I409-A443 PolarHBondContact N-O 3.06Å; I409-A443 PolarHBondContact O-N 2.95Å; L417-A443 HydrophobicContact CD1-CB 3.49Å; L417-A443 VanDerWaalsContact CD1-CB 3.49Å; S428-A443 WeakPolarHBondContact O-CA 3.45Å; F429-A443 HydrophobicContact CD1-CB 3.98Å; F429-A443 HydrophobicContact CE1-CB 4.02Å; A443-Y445 HydrophobicContact CB-CE2 4.25Å
444T96.8Very high87.5Confident22 Ų2262.6 Ų62.614%0.13533%0.327CS..EExtended strand (participates in β ladder)trans-120122.3173.3-57.50000109.6N406 V427 S428 R446N406-T444 HydrophobicContact CB-CG2 4.4Å; V427-T444 WeakPolarHBondContact CA-O 2.94Å; S428-T444 PolarHBondContact N-O 3.48Å; S428-T444 PolarHBondContact O-N 3.36Å; S428-T444 PolarHBondContact OG-O 2.67Å; T444-R446 HydrophobicContact CG2-CG 4.35Å
445Y96.2Very high88.5Confident4 Ų461.4 Ų61.42%0.01632%0.315CS..EExtended strand (participates in β ladder)trans-97.4115.3172.2-72.9-98.5000109.1N406 V407 I409 L417 A425 V427 A443 L454 L456N406-Y445 CarbonylContact C-O 3.5Å; N406-Y445 WeakPolarHBondContact CA-O 3.42Å; N406-Y445 WeakPolarHBondContact CB-O 3.27Å; V407-Y445 PolarHBondContact N-O 3.34Å; V407-Y445 PolarHBondContact O-N 2.84Å; I409-Y445 HydrophobicContact CG1-CD2 4.19Å; I409-Y445 HydrophobicContact CG1-CE2 4.18Å; L417-Y445 HydrophobicContact CD1-CE2 3.81Å; L417-Y445 WeakPolarHBondContact CD1-OH 3.39Å; A425-Y445 HydrophobicContact CB-CD1 4.07Å; V427-Y445 HydrophobicContact CB-CD1 4.46Å; V427-Y445 HydrophobicContact CB-CE1 4.17Å; V427-Y445 HydrophobicContact CG1-CD1 4.45Å; V427-Y445 HydrophobicContact CG1-CD2 4.49Å; V427-Y445 HydrophobicContact CG1-CE1 4Å; V427-Y445 HydrophobicContact CG1-CE2 4.01Å; V427-Y445 HydrophobicContact CG2-CD1 3.6Å; V427-Y445 HydrophobicContact CG2-CE1 3.18Å; V427-Y445 HydrophobicContact CG2-CG 4.49Å; A443-Y445 HydrophobicContact CB-CE2 4.25Å; Y445-L454 HydrophobicContact CG-CD2 4.31Å; Y445-L456 HydrophobicContact CD1-CD2 3.68Å; Y445-L456 HydrophobicContact CD2-CD1 4.32Å; Y445-L456 HydrophobicContact CD2-CD2 4.09Å; Y445-L456 HydrophobicContact CE1-CD2 3.32Å; Y445-L456 HydrophobicContact CE2-CD1 4.17Å; Y445-L456 HydrophobicContact CE2-CD2 3.79Å; Y445-L456 HydrophobicContact CG-CD2 4.05Å; Y445-L456 VanDerWaalsContact CZ-CD2 3.41Å
446R95.3Very high89.4Confident168 Ų16852 Ų5263%0.63427%0.271SS*.EExtended strand (participates in β ladder)trans-95.9113.5172.5-66.8-176.5-177173.72.6109.1A425 V426 T444A425-R446 VanDerWaalsContact CA-O 3.29Å; A425-R446 WeakPolarHBondContact CA-O 3.18Å; A425-R446 WeakPolarHBondContact CB-O 3.43Å; V426-R446 PolarHBondContact N-O 3.47Å; V426-R446 PolarHBondContact O-N 2.77Å; T444-R446 HydrophobicContact CG2-CG 4.35Å
447C91Very high90.3Very high7 Ų750.4 Ų50.45%0.04725%0.254CS..PPolyproline II helixtrans-80.4137.8-176.1-66.50000110.7I404 D405 T451 R475I404-C447 HydrophobicContact CB-CB 4.24Å; I404-C447 HydrophobicContact CG2-CB 4.38Å; I404-C447 WeakPolarHBondContact O-CB 3.47Å; D405-C447 PolarHBondContact O-N 2.62Å; D405-C447 VanDerWaalsContact O-N 3.15Å; C447-T451 HydrophobicContact CB-CG2 4.36Å; C447-R475 PolarHBondContact O-NH2 2.84Å
448Q84.1Confident91.3Very high108 Ų10845.7 Ų45.751%0.50523%0.229SC..PPolyproline II helixtrans-67.5165.9170.6-63-173.213.600110.4S424 N450 T451S424-Q448 WeakPolarHBondContact O-CG 3.41Å; S424-Q448 PolarHBondContact O-NE2 2.96Å; Q448-N450 PolarHBondContact O-N 2.84Å; Q448-T451 PolarHBondContact O-N 3.22Å; Q448-T451 PolarHBondContact O-OG1 3.34Å
449A78.9Confident91.9Very high65 Ų6541.5 Ų41.554%0.53721%0.205SC..THydrogen-bonded Turntrans-54.4142-175.600000112.2T451A449-T451 VanDerWaalsContact C-N 3.29Å; A449-T451 PolarHBondContact O-N 2.89Å
450N83.6Confident92.1Very high140 Ų14040.1 Ų40.175%0.74920%0.198SC*.THydrogen-bonded Turntrans64.719.2175.9-53.8-25.7000116.6Q448 T452Q448-N450 PolarHBondContact O-N 2.84Å; N450-T452 PolarHBondContact O-N 3.16Å
451T90.8Very high92.1Very high22 Ų2239.1 Ų39.114%0.13520%0.196CC..  trans-81.7110173.2-50.60000110.3A403 I404 C447 Q448 A449 R453A403-T451 CarbonylContact C-O 3.13Å; A403-T451 WeakPolarHBondContact CA-O 3.36Å; I404-T451 PolarHBondContact N-O 2.74Å; C447-T451 HydrophobicContact CB-CG2 4.36Å; Q448-T451 PolarHBondContact O-N 3.22Å; Q448-T451 PolarHBondContact O-OG1 3.34Å; A449-T451 VanDerWaalsContact C-N 3.29Å; A449-T451 PolarHBondContact O-N 2.89Å; T451-R453 WeakPolarHBondContact CG2-O 3.34Å
452T91.9Very high91.9Very high15 Ų1539.4 Ų39.49%0.09220%0.197CC..  trans-96-22.3177.546.50000113.1E399 V400 N450E399-T452 WeakPolarHBondContact CA-O 3.38Å; V400-T452 PolarHBondContact N-O 3.01Å; V400-T452 WeakPolarHBondContact O-CB 3.46Å; N450-T452 PolarHBondContact O-N 3.16Å
453R92.7Very high91.7Very high40 Ų4039 Ų3915%0.15120%0.201CC..EExtended strand (participates in β ladder)trans-122.3133.6-179.9-176.4-178-178.5-75.53.9110.5D262 I397 L398 E399 T451 E455D262-R453 PolarHBondContact O-NE 2.82Å; I397-R453 VanDerWaalsContact CD1-NH2 3.29Å; I397-R453 HydrophobicContact CG2-CG 4.05Å; L398-R453 CarbonylContact O-C 3.54Å; L398-R453 WeakPolarHBondContact O-CA 3.47Å; E399-R453 HydrophobicContact CB-CB 4.39Å; E399-R453 HydrophobicContact CB-CG 4.33Å; E399-R453 HydrophobicContact CG-CB 4.2Å; T451-R453 WeakPolarHBondContact CG2-O 3.34Å; R453-E455 IonicContact CZ-OE2 3.73Å; R453-E455 IonicContact NH1-OE2 3.99Å; R453-E455 PolarHBondContact NH1-OE2 3.23Å; R453-E455 IonicContact NH2-OE2 2.69Å; R453-E455 PolarHBondContact NH2-OE2 3.14Å; R453-E455 VanDerWaalsContact NH2-OE2 3.15Å
454L93.5Very high91.5Very high2 Ų242.4 Ų42.41%0.0122%0.217CC..EExtended strand (participates in β ladder)trans-123.7131.3174-176.668.1000109.4I397 L398 I404 V407 N423 A425 Y445 L456I397-L454 WeakPolarHBondContact CA-O 3.48Å; L398-L454 PolarHBondContact N-O 2.96Å; L398-L454 PolarHBondContact O-N 2.88Å; I404-L454 HydrophobicContact CD1-CB 4.23Å; V407-L454 HydrophobicContact CB-CD2 3.82Å; V407-L454 HydrophobicContact CG1-CD2 4.4Å; V407-L454 HydrophobicContact CG2-CD2 3.54Å; N423-L454 WeakPolarHBondContact ND2-CD1 3.05Å; N423-L454 VanDerWaalsContact OD1-CD1 3.22Å; N423-L454 WeakPolarHBondContact OD1-CD1 3.19Å; A425-L454 HydrophobicContact CB-CD1 3.98Å; Y445-L454 HydrophobicContact CG-CD2 4.31Å; L454-L456 HydrophobicContact CD1-CD2 4.24Å; L454-L456 HydrophobicContact CD2-CD1 4.24Å; L454-L456 HydrophobicContact CD2-CD2 4.04Å; L454-L456 HydrophobicContact CD2-CG 4.23Å; L454-L456 HydrophobicContact CG-CD2 3.96Å; L454-L456 HydrophobicContact CG-CG 4.17Å
455E93.2Very high91.5Very high39 Ų3944.1 Ų44.118%0.18222%0.222CC..EExtended strand (participates in β ladder)trans-118.8128.5175.9-177.6172.4157.100109.9L396 I397 N423 R453L396-E455 WeakPolarHBondContact O-CA 3.28Å; I397-E455 HydrophobicContact CG1-CB 4.26Å; I397-E455 HydrophobicContact CG1-CG 3.89Å; N423-E455 PolarHBondContact ND2-O 3.19Å; R453-E455 IonicContact CZ-OE2 3.73Å; R453-E455 IonicContact NH1-OE2 3.99Å; R453-E455 PolarHBondContact NH1-OE2 3.23Å; R453-E455 IonicContact NH2-OE2 2.69Å; R453-E455 PolarHBondContact NH2-OE2 3.14Å; R453-E455 VanDerWaalsContact NH2-OE2 3.15Å
456L93.3Very high91.5Very high1 Ų144.7 Ų44.71%0.00523%0.229CC..EExtended strand (participates in β ladder)trans-126134.3-177.1-54.8178000108.9S395 L396 I409 Y445 L454S395-L456 WeakPolarHBondContact CA-O 3.44Å; L396-L456 HydrophobicContact CB-CB 4.34Å; L396-L456 HydrophobicContact CD2-CD1 4.42Å; L396-L456 PolarHBondContact N-O 2.97Å; L396-L456 PolarHBondContact O-N 2.75Å; I409-L456 HydrophobicContact CD1-CD1 3.65Å; I409-L456 HydrophobicContact CG1-CD1 3.82Å; Y445-L456 HydrophobicContact CD1-CD2 3.68Å; Y445-L456 HydrophobicContact CD2-CD1 4.32Å; Y445-L456 HydrophobicContact CD2-CD2 4.09Å; Y445-L456 HydrophobicContact CE1-CD2 3.32Å; Y445-L456 HydrophobicContact CE2-CD1 4.17Å; Y445-L456 HydrophobicContact CE2-CD2 3.79Å; Y445-L456 HydrophobicContact CG-CD2 4.05Å; Y445-L456 VanDerWaalsContact CZ-CD2 3.41Å; L454-L456 HydrophobicContact CD1-CD2 4.24Å; L454-L456 HydrophobicContact CD2-CD1 4.24Å; L454-L456 HydrophobicContact CD2-CD2 4.04Å; L454-L456 HydrophobicContact CD2-CG 4.23Å; L454-L456 HydrophobicContact CG-CD2 3.96Å; L454-L456 HydrophobicContact CG-CG 4.17Å
457K93.4Very high91.5Very high45 Ų4538.1 Ų38.120%0.19621%0.208CC..EExtended strand (participates in β ladder)trans-100.2130.9171.7-79.2-171.1179.4-165.20110.2D391 Y394 L417 L418 V420D391-K457 IonicContact OD2-NZ 3.53Å; D391-K457 PolarHBondContact OD2-NZ 3.29Å; Y394-K457 CarbonylContact O-C 3.55Å; Y394-K457 WeakPolarHBondContact O-CA 3.29Å; L417-K457 WeakPolarHBondContact CA-O 3.41Å; L418-K457 HydrophobicContact CB-CB 3.8Å; L418-K457 HydrophobicContact CD1-CB 4.28Å; L418-K457 HydrophobicContact CG-CB 4.39Å; L418-K457 PolarHBondContact N-O 2.93Å; V420-K457 HydrophobicContact CG2-CB 4.06Å; V420-K457 HydrophobicContact CG2-CD 4.22Å; V420-K457 HydrophobicContact CG2-CG 3.81Å
458I95.1Very high91.8Very high0 Ų037.8 Ų37.80%021%0.205CC..EExtended strand (participates in β ladder)trans-127.9117.5-171.6-51.9-173.4000108.4F385 Y394 L396 I415 D416 L417 L468F385-I458 HydrophobicContact CE2-CD1 4.22Å; Y394-I458 PolarHBondContact N-O 3Å; Y394-I458 PolarHBondContact O-N 3.06Å; L396-I458 HydrophobicContact CB-CD1 3.98Å; L396-I458 HydrophobicContact CD2-CD1 4.09Å; I415-I458 HydrophobicContact CB-CG2 4.01Å; I415-I458 HydrophobicContact CD1-CG2 3.65Å; I415-I458 HydrophobicContact CG1-CG2 4.46Å; I415-I458 HydrophobicContact CG2-CG2 4.18Å; D416-I458 WeakPolarHBondContact O-CA 3.46Å; L417-I458 HydrophobicContact CD2-CD1 4.23Å; L417-I458 HydrophobicContact CD2-CG1 3.79Å; L417-I458 HydrophobicContact CD2-CG2 4.47Å; I458-L468 HydrophobicContact CD1-CD1 4.48Å; I458-L468 HydrophobicContact CD1-CD2 3.29Å; I458-L468 HydrophobicContact CD1-CG 4.5Å
459R93.4Very high92.4Very high17 Ų1734.3 Ų34.36%0.06419%0.189CC..EExtended strand (participates in β ladder)trans-94.1129.4173.4-169.7175.6-71.2153.3-2.5109I415 D416I415-R459 VanDerWaalsContact CA-O 3.32Å; I415-R459 WeakPolarHBondContact CA-O 3.43Å; I415-R459 WeakPolarHBondContact CB-O 3.4Å; D416-R459 HydrophobicContact CB-CB 4.05Å; D416-R459 PolarHBondContact N-O 3.41Å; D416-R459 PolarHBondContact O-N 2.69Å
460S93.9Very high93.4Very high1 Ų131.2 Ų31.21%0.00716%0.164CC..EExtended strand (participates in β ladder)trans-109.9157.6174.564.80000110.5S492S460-S492 WeakPolarHBondContact OG-CB 3.27Å; S460-S492 PolarHBondContact OG-OG 2.91Å
461I91.6Very high94Very high69 Ų6928.3 Ų28.335%0.35414%0.143SC..  trans-105.7127.1174.9-56.6174.4000107.7P414 Q464P414-I461 HydrophobicContact CB-CD1 4.47Å; I461-Q464 HydrophobicContact CB-CG 4.42Å; I461-Q464 HydrophobicContact CG2-CG 4.4Å; I461-Q464 PolarHBondContact O-N 2.93Å
462E89.6Confident94.4Very high25 Ų2527.3 Ų27.312%0.11714%0.136CC..THydrogen-bonded Turntrans-65.7139.9-179-160.9154.9-153.700110.8Q464 L491 L493 H494 N547 I575E462-Q464 VanDerWaalsContact C-N 3.28Å; E462-Q464 PolarHBondContact O-N 3.43Å; E462-L491 HydrophobicContact CG-CD2 4.06Å; E462-L491 WeakPolarHBondContact OE1-CA 3.29Å; E462-L491 WeakPolarHBondContact OE1-CD2 3.25Å; E462-L493 HydrophobicContact CB-CD1 4.12Å; E462-H494 IonicContact OE1-CE1 3.92Å; E462-H494 PolarHBondContact OE1-CE1 3.12Å; E462-H494 IonicContact OE1-ND1 3.94Å; E462-H494 PolarHBondContact OE1-ND1 2.98Å; E462-N547 PolarHBondContact OE2-ND2 2.79Å; E462-I575 HydrophobicContact CB-CD1 4.5Å; E462-I575 HydrophobicContact CG-CD1 3.91Å
463G90.9Very high94.6Very high28 Ų2827.4 Ų27.429%0.28914%0.137SC..THydrogen-bonded Turntrans87.5-17.9-172.100000114.7P490G463-P490 PolarHBondContact N-O 3.22Å
464Q93.1Very high94.7Very high73 Ų7325.5 Ų25.534%0.34113%0.13SC..  trans-100.1114.5173-59.3-178.8800109.8P414 I461 E462P414-Q464 VanDerWaalsContact CB-OE1 3.28Å; I461-Q464 HydrophobicContact CB-CG 4.42Å; I461-Q464 HydrophobicContact CG2-CG 4.4Å; I461-Q464 PolarHBondContact O-N 2.93Å; E462-Q464 VanDerWaalsContact C-N 3.28Å; E462-Q464 PolarHBondContact O-N 3.43Å
465Y95.9Very high94.7Very high57 Ų5730.9 Ų30.922%0.22415%0.15CC..  trans-133.1148.3-170.663-89.7000112.1V413 I488 P490 F526 V579V413-Y465 VanDerWaalsContact CG1-O 3.29Å; V413-Y465 WeakPolarHBondContact CG1-O 3.37Å; Y465-I488 WeakPolarHBondContact CA-O 3.31Å; Y465-I488 VanDerWaalsContact CB-O 3.29Å; Y465-I488 WeakPolarHBondContact CB-O 3.29Å; Y465-P490 HydrophobicContact CD1-CB 3.98Å; Y465-P490 HydrophobicContact CD1-CG 3.74Å; Y465-P490 HydrophobicContact CD2-CG 4.23Å; Y465-P490 HydrophobicContact CE1-CG 4.4Å; Y465-P490 HydrophobicContact CG-CB 4.27Å; Y465-P490 HydrophobicContact CG-CG 3.64Å; Y465-F526 AromaticContact CD2-CE1 3.89Å; Y465-F526 HydrophobicContact CD2-CE1 3.89Å; Y465-F526 AromaticContact CD2-CZ 3.66Å; Y465-F526 HydrophobicContact CD2-CZ 3.66Å; Y465-F526 AromaticContact CE2-CE1 3.77Å; Y465-F526 HydrophobicContact CE2-CE1 3.77Å; Y465-F526 AromaticContact CE2-CZ 3.64Å; Y465-F526 HydrophobicContact CE2-CZ 3.64Å; Y465-V579 HydrophobicContact CD1-CG2 4.24Å; Y465-V579 HydrophobicContact CE1-CG2 3.66Å
466G95.6Very high94.6Very high16 Ų1630.8 Ų30.817%0.16515%0.15CC..EExtended strand (participates in β ladder)trans169.4-155.2-172.900000112.6D412 H487 I488D412-G466 VanDerWaalsContact OD1-CA 3.29Å; D412-G466 WeakPolarHBondContact OD1-CA 3.38Å; G466-H487 WeakPolarHBondContact O-CA 3.42Å; G466-I488 PolarHBondContact N-O 2.85Å; G466-I488 VanDerWaalsContact N-O 3.09Å; G466-I488 PolarHBondContact O-N 3Å
467T95.9Very high94.3Very high31 Ų3136.4 Ų36.419%0.1918%0.177CC..EExtended strand (participates in β ladder)trans-114.5129.9-172.7-41.60000111.6D412 Q469 Q485 Y486D412-T467 PolarHBondContact N-O 3.37Å; D412-T467 PolarHBondContact OD1-N 2.9Å; D412-T467 VanDerWaalsContact OD1-O 3.08Å; D412-T467 WeakPolarHBondContact OD2-CB 3.19Å; D412-T467 PolarHBondContact OD2-N 3.05Å; D412-T467 PolarHBondContact OD2-OG1 2.76Å; T467-Q469 HydrophobicContact CG2-CG 4.12Å; T467-Q485 HydrophobicContact CG2-CB 4.19Å; T467-Q485 HydrophobicContact CG2-CG 4.48Å; T467-Y486 WeakPolarHBondContact CA-O 3.41Å
468L97.2Very high94.1Very high0 Ų036.2 Ų36.20%018%0.18CC..EExtended strand (participates in β ladder)trans-103.8124.8167.3178.475.5000108.9F385 L396 I409 I415 I458 Y486F385-L468 HydrophobicContact CE2-CD2 4.15Å; F385-L468 HydrophobicContact CZ-CD2 4.45Å; L396-L468 HydrophobicContact CD2-CD2 4.19Å; I409-L468 HydrophobicContact CG2-CD1 3.53Å; I409-L468 HydrophobicContact CG2-CG 4.47Å; I415-L468 HydrophobicContact CD1-CD1 3.52Å; I458-L468 HydrophobicContact CD1-CD1 4.48Å; I458-L468 HydrophobicContact CD1-CD2 3.29Å; I458-L468 HydrophobicContact CD1-CG 4.5Å; L468-Y486 HydrophobicContact CD2-CD2 4.22Å; L468-Y486 PolarHBondContact N-O 3.5Å; L468-Y486 PolarHBondContact O-N 2.84Å
469Q97.6Very high94Very high35 Ų3542.5 Ų42.516%0.16421%0.207CC..EExtended strand (participates in β ladder)trans-110.4132.4178.4-54.5-170.3-10.700111.1I409 Q410 T467 Y471 V483 R484 Q485I409-Q469 WeakPolarHBondContact CA-O 3.49Å; Q410-Q469 HydrophobicContact CB-CB 4.42Å; Q410-Q469 PolarHBondContact N-O 3.18Å; Q410-Q469 PolarHBondContact O-N 3.48Å; T467-Q469 HydrophobicContact CG2-CG 4.12Å; Q469-Y471 HydrophobicContact CB-CD2 4.37Å; Q469-Y471 HydrophobicContact CB-CE2 3.72Å; Q469-Y471 PolarHBondContact OE1-OH 2.83Å; Q469-V483 HydrophobicContact CB-CG2 4.23Å; Q469-R484 CarbonylContact C-O 3.58Å; Q469-R484 VanDerWaalsContact CA-O 3.31Å; Q469-R484 WeakPolarHBondContact CA-O 3.43Å; Q469-Q485 HydrophobicContact CG-CG 4.21Å; Q469-Q485 VanDerWaalsContact NE2-NE2 3.19Å
470A98.1Very high94Very high0 Ų042.5 Ų42.50%021%0.209CC..EExtended strand (participates in β ladder)trans-117.4117.5173.300000110.3L396 L398 V407 L408 I409 V483 R484 Y486L396-A470 HydrophobicContact CD2-CB 4.42Å; L398-A470 HydrophobicContact CD1-CB 4.11Å; V407-A470 HydrophobicContact CG1-CB 4.44Å; L408-A470 CarbonylContact O-C 3.57Å; L408-A470 WeakPolarHBondContact O-CA 3.41Å; I409-A470 HydrophobicContact CD1-CB 3.76Å; A470-V483 CarbonylContact O-C 3.51Å; A470-V483 WeakPolarHBondContact O-CA 3.32Å; A470-R484 PolarHBondContact N-O 2.86Å; A470-R484 PolarHBondContact O-N 3.27Å; A470-Y486 HydrophobicContact CB-CE2 3.93Å
471Y98Very high94.1Very high79 Ų7945.2 Ų45.231%0.3123%0.227SC..EExtended strand (participates in β ladder)trans-99.8105.3179-68.7-95.3000108.6V407 L408 Q410 Q469 C481 V483V407-Y471 VanDerWaalsContact CA-O 3.3Å; V407-Y471 WeakPolarHBondContact CA-O 3.24Å; L408-Y471 HydrophobicContact CD2-CD2 3.63Å; L408-Y471 HydrophobicContact CD2-CE2 4.16Å; L408-Y471 HydrophobicContact CD2-CG 4.37Å; L408-Y471 PolarHBondContact N-O 3.27Å; L408-Y471 PolarHBondContact O-N 2.93Å; Q410-Y471 HydrophobicContact CB-CE2 4.3Å; Q469-Y471 HydrophobicContact CB-CD2 4.37Å; Q469-Y471 HydrophobicContact CB-CE2 3.72Å; Q469-Y471 PolarHBondContact OE1-OH 2.83Å; Y471-C481 VanDerWaalsContact CB-SG 3.59Å; Y471-V483 HydrophobicContact CD1-CB 3.96Å; Y471-V483 HydrophobicContact CD1-CG2 4.08Å; Y471-V483 HydrophobicContact CD2-CG2 4.42Å; Y471-V483 HydrophobicContact CE1-CB 3.88Å; Y471-V483 HydrophobicContact CE1-CG2 3.76Å; Y471-V483 HydrophobicContact CE2-CG2 4.11Å; Y471-V483 HydrophobicContact CG-CG2 4.4Å
472V97.8Very high94.3Very high0 Ų043.9 Ų43.90%022%0.22CC..EExtended strand (participates in β ladder)trans-101.4120.1-173.7-174.90000109.9I381 L398 V400 V407 C481 Q482I381-V472 HydrophobicContact CD1-CB 3.76Å; I381-V472 HydrophobicContact CD1-CG1 4.27Å; I381-V472 HydrophobicContact CD1-CG2 3.94Å; L398-V472 HydrophobicContact CD1-CG2 3.95Å; L398-V472 HydrophobicContact CD2-CG2 4.42Å; V400-V472 HydrophobicContact CG2-CG1 3.82Å; V407-V472 HydrophobicContact CG1-CG2 4.34Å; V407-V472 HydrophobicContact CG2-CG1 4.39Å; V407-V472 HydrophobicContact CG2-CG2 4.39Å; V472-C481 WeakPolarHBondContact O-CA 3.46Å; V472-Q482 PolarHBondContact N-O 2.81Å; V472-Q482 PolarHBondContact O-N 3.09Å; V472-Q482 VanDerWaalsContact O-N 3.13Å
473T96.8Very high94.6Very high17 Ų1746 Ų4610%0.10423%0.234CC..EExtended strand (participates in β ladder)trans-113107.9177.1-57.80000109.8D405 N406D405-T473 WeakPolarHBondContact CA-O 3.43Å; D405-T473 HydrophobicContact CB-CG2 4.3Å; D405-T473 VanDerWaalsContact CB-O 3.28Å; D405-T473 WeakPolarHBondContact CB-O 3.49Å; D405-T473 PolarHBondContact N-O 2.96Å; N406-T473 PolarHBondContact N-O 2.98Å; N406-T473 PolarHBondContact O-N 3.14Å
474P94.9Very high95Very high0 Ų048.3 Ų48.30%023%0.234CC..EExtended strand (participates in β ladder)trans-79.7161.517326.7-28.3000113F379 V400 T402 I476 T480F379-P474 HydrophobicContact CD1-CG 3.9Å; F379-P474 HydrophobicContact CD2-CG 4.06Å; F379-P474 HydrophobicContact CE1-CG 3.66Å; F379-P474 HydrophobicContact CE2-CG 3.78Å; F379-P474 HydrophobicContact CG-CG 4.1Å; F379-P474 HydrophobicContact CZ-CG 3.59Å; V400-P474 HydrophobicContact CG1-CB 4.19Å; T402-P474 VanDerWaalsContact OG1-CB 3.24Å; T402-P474 WeakPolarHBondContact OG1-CB 3.43Å; P474-I476 HydrophobicContact CB-CG1 4.48Å; P474-I476 HydrophobicContact CB-CG2 4.35Å; P474-I476 HydrophobicContact CG-CD1 3.82Å; P474-I476 HydrophobicContact CG-CG1 3.95Å; P474-I476 PolarHBondContact O-N 2.9Å; P474-T480 WeakPolarHBondContact CD-O 3.41Å
475R93Very high95.2Very high116 Ų11650.3 Ų50.344%0.43824%0.243SC..SBendtrans-7961.7172.9-64.5-174.1-177-165.60.6111.7A403 D405 C447A403-R475 WeakPolarHBondContact O-CB 3.43Å; A403-R475 WeakPolarHBondContact O-CG 3.4Å; A403-R475 PolarHBondContact O-N 2.83Å; D405-R475 HydrophobicContact CB-CG 3.79Å; D405-R475 IonicContact OD1-NE 3.12Å; C447-R475 PolarHBondContact O-NH2 2.84Å
476I90.8Very high95.2Very high36 Ų3648.4 Ų48.419%0.18524%0.236CC..  trans-116.7160.9173.965.2-177.6000111.4P377 F379 T402 P474 P478 K479 T480P377-I476 HydrophobicContact CB-CD1 4.17Å; P377-I476 HydrophobicContact CG-CD1 3.91Å; P377-I476 HydrophobicContact CG-CG1 4.49Å; F379-I476 HydrophobicContact CD1-CD1 4.05Å; T402-I476 HydrophobicContact CG2-CG2 3.73Å; P474-I476 HydrophobicContact CB-CG1 4.48Å; P474-I476 HydrophobicContact CB-CG2 4.35Å; P474-I476 HydrophobicContact CG-CD1 3.82Å; P474-I476 HydrophobicContact CG-CG1 3.95Å; P474-I476 PolarHBondContact O-N 2.9Å; I476-P478 CarbonylContact O-C 3.55Å; I476-K479 PolarHBondContact O-N 3.33Å; I476-T480 HydrophobicContact CD1-CG2 3.61Å; I476-T480 HydrophobicContact CG1-CG2 4.1Å
477Q87.8Confident95.3Very high120 Ų12052.6 Ų52.656%0.56125%0.251SS*.SBendtrans-123124.6176.6-170.167.928.100109.4
478P89.3Confident95.3Very high40 Ų4051.3 Ų51.326%0.2624%0.243SC..SBendcis-63.1148.7-3.7-20.933.4000113.7Y363 P377 I476 T480Y363-P478 HydrophobicContact CE1-CG 4.35Å; P377-P478 WeakPolarHBondContact CG-O 3.18Å; I476-P478 CarbonylContact O-C 3.55Å; P478-T480 PolarHBondContact O-N 3.05Å
479K91.8Very high95.3Very high132 Ų13253.5 Ų53.557%0.57425%0.252SS*.  trans-63.2135.7172.2-73.7-161.9177-162.40109.6D405 I476D405-K479 IonicContact OD2-NZ 3.52Å; D405-K479 PolarHBondContact OD2-NZ 2.98Å; I476-K479 PolarHBondContact O-N 3.33Å
480T94Very high95.3Very high17 Ų1752 Ų5210%0.10425%0.245CC..  trans-142.1156177.9176.70000108.6V376 P377 F379 P474 I476 P478V376-T480 HydrophobicContact CG1-CG2 4.5Å; V376-T480 WeakPolarHBondContact CG1-OG1 3.48Å; P377-T480 HydrophobicContact CG-CG2 3.77Å; F379-T480 HydrophobicContact CD1-CG2 3.91Å; F379-T480 HydrophobicContact CE1-CG2 3.58Å; P474-T480 WeakPolarHBondContact CD-O 3.41Å; I476-T480 HydrophobicContact CD1-CG2 3.61Å; I476-T480 HydrophobicContact CG1-CG2 4.1Å; P478-T480 PolarHBondContact O-N 3.05Å
481C95.7Very high95.3Very high58 Ų5852 Ų5239%0.39225%0.245SC..  trans-126.6135175.3177.50000108.2Y471 V472Y471-C481 VanDerWaalsContact CB-SG 3.59Å; V472-C481 WeakPolarHBondContact O-CA 3.46Å
482Q96.2Very high95.2Very high42 Ų4248.2 Ų48.220%0.19623%0.23CC..EExtended strand (participates in β ladder)trans-111.8134.4168.6-74.5-175.712.300109.4F379 I381 V472F379-Q482 HydrophobicContact CD1-CG 4.39Å; F379-Q482 HydrophobicContact CE1-CB 4.27Å; F379-Q482 HydrophobicContact CE1-CG 3.61Å; F379-Q482 HydrophobicContact CE2-CB 4.4Å; F379-Q482 HydrophobicContact CE2-CG 4.35Å; F379-Q482 HydrophobicContact CZ-CB 3.76Å; F379-Q482 HydrophobicContact CZ-CG 3.6Å; F379-Q482 PolarHBondContact O-NE2 2.64Å; F379-Q482 PolarHBondContact O-OE1 3.3Å; I381-Q482 HydrophobicContact CD1-CB 3.77Å; V472-Q482 PolarHBondContact N-O 2.81Å; V472-Q482 PolarHBondContact O-N 3.09Å; V472-Q482 VanDerWaalsContact O-N 3.13Å
483V97.2Very high95.2Very high68 Ų6848.2 Ų48.241%0.41223%0.231SC..EExtended strand (participates in β ladder)trans-92.6135.9174.462.70000110.1Q469 A470 Y471 Q485Q469-V483 HydrophobicContact CB-CG2 4.23Å; A470-V483 CarbonylContact O-C 3.51Å; A470-V483 WeakPolarHBondContact O-CA 3.32Å; Y471-V483 HydrophobicContact CD1-CB 3.96Å; Y471-V483 HydrophobicContact CD1-CG2 4.08Å; Y471-V483 HydrophobicContact CD2-CG2 4.42Å; Y471-V483 HydrophobicContact CE1-CB 3.88Å; Y471-V483 HydrophobicContact CE1-CG2 3.76Å; Y471-V483 HydrophobicContact CE2-CG2 4.11Å; Y471-V483 HydrophobicContact CG-CG2 4.4Å; V483-Q485 HydrophobicContact CG2-CG 4.45Å
484R97.8Very high95.2Very high77 Ų7747.4 Ų47.429%0.29123%0.226SC..EExtended strand (participates in β ladder)trans-115.7138.9168.1-63.9-70.7166170.2-5108.8I381 Q469 A470 Y486I381-R484 HydrophobicContact CD1-CG 4.12Å; Q469-R484 CarbonylContact C-O 3.58Å; Q469-R484 VanDerWaalsContact CA-O 3.31Å; Q469-R484 WeakPolarHBondContact CA-O 3.43Å; A470-R484 PolarHBondContact N-O 2.86Å; A470-R484 PolarHBondContact O-N 3.27Å; R484-Y486 HydrophobicContact CB-CE2 3.8Å; R484-Y486 WeakPolarHBondContact CB-OH 3.33Å
485Q97.4Very high95.2Very high115 Ų11548.3 Ų48.354%0.53723%0.23SC..EExtended strand (participates in β ladder)trans-118126.2-178.6-64.1-174.9-29.200109.4T467 Q469 V483T467-Q485 HydrophobicContact CG2-CB 4.19Å; T467-Q485 HydrophobicContact CG2-CG 4.48Å; Q469-Q485 HydrophobicContact CG-CG 4.21Å; Q469-Q485 VanDerWaalsContact NE2-NE2 3.19Å; V483-Q485 HydrophobicContact CG2-CG 4.45Å
486Y97.2Very high95.3Very high17 Ų1744.6 Ų44.67%0.06722%0.216CC..EExtended strand (participates in β ladder)trans-119.1151176.7-48.7-80.7000109D383 F385 L396 L398 T467 L468 A470 R484D383-Y486 HydrophobicContact CB-CE1 4.3Å; D383-Y486 WeakPolarHBondContact CB-OH 3.5Å; D383-Y486 WeakPolarHBondContact OD2-CE1 3.31Å; D383-Y486 PolarHBondContact OD2-OH 3.4Å; D383-Y486 VanDerWaalsContact OD2-OH 3.08Å; F385-Y486 HydrophobicContact CB-CD1 3.64Å; F385-Y486 HydrophobicContact CB-CE1 4.05Å; F385-Y486 HydrophobicContact CB-CG 4.34Å; F385-Y486 HydrophobicContact CD1-CD1 4.36Å; F385-Y486 HydrophobicContact CD1-CG 4.42Å; F385-Y486 HydrophobicContact CD2-CG 4.49Å; F385-Y486 AromaticContact CG-CD1 3.95Å; F385-Y486 HydrophobicContact CG-CD1 3.95Å; F385-Y486 HydrophobicContact CG-CG 4.17Å; L396-Y486 HydrophobicContact CD1-CD1 4.41Å; L396-Y486 HydrophobicContact CD1-CD2 4.2Å; L396-Y486 HydrophobicContact CD1-CE1 3.86Å; L396-Y486 HydrophobicContact CD1-CE2 3.61Å; L396-Y486 VanDerWaalsContact CD1-CZ 3.42Å; L396-Y486 HydrophobicContact CD2-CD2 4.3Å; L396-Y486 HydrophobicContact CD2-CE2 3.94Å; L396-Y486 HydrophobicContact CG-CE2 4.45Å; L398-Y486 WeakPolarHBondContact CD2-OH 3.47Å; T467-Y486 WeakPolarHBondContact CA-O 3.41Å; L468-Y486 HydrophobicContact CD2-CD2 4.22Å; L468-Y486 PolarHBondContact N-O 3.5Å; L468-Y486 PolarHBondContact O-N 2.84Å; A470-Y486 HydrophobicContact CB-CE2 3.93Å; R484-Y486 HydrophobicContact CB-CE2 3.8Å; R484-Y486 WeakPolarHBondContact CB-OH 3.33Å
487H95.9Very high95.5Very high105 Ų10544 Ų4449%0.48621%0.214SC..EExtended strand (participates in β ladder)trans-109.3122-177.9-63.386.5000109.8G466G466-H487 WeakPolarHBondContact O-CA 3.42Å
488I97.1Very high95.7Very high4 Ų440.9 Ų40.92%0.02120%0.199CC..EExtended strand (participates in β ladder)trans-83.4113.9164.9-56.1-58.7000106.8F385 V413 Y465 G466F385-I488 HydrophobicContact CE1-CD1 4.02Å; F385-I488 HydrophobicContact CZ-CD1 3.56Å; V413-I488 HydrophobicContact CG2-CB 4.18Å; V413-I488 HydrophobicContact CG2-CG1 3.99Å; Y465-I488 WeakPolarHBondContact CA-O 3.31Å; Y465-I488 VanDerWaalsContact CB-O 3.29Å; Y465-I488 WeakPolarHBondContact CB-O 3.29Å; G466-I488 PolarHBondContact N-O 2.85Å; G466-I488 VanDerWaalsContact N-O 3.09Å; G466-I488 PolarHBondContact O-N 3Å
489K97.3Very high95.9Very high46 Ų4645.9 Ų45.920%0.222%0.217CC..  trans-77.8153.5-175.7-59-71.8177.9171.10110.6L491 S492 V525 F526 P529K489-L491 VanDerWaalsContact C-N 3.29Å; K489-L491 PolarHBondContact O-N 2.89Å; K489-S492 WeakPolarHBondContact O-CB 3.39Å; K489-S492 PolarHBondContact O-N 2.8Å; K489-S492 VanDerWaalsContact O-N 3.08Å; K489-V525 PolarHBondContact NZ-O 3.49Å; K489-F526 WeakPolarHBondContact CD-O 3.22Å; K489-P529 HydrophobicContact CB-CG 4.33Å; K489-P529 HydrophobicContact CG-CG 4.31Å
490P97.8Very high96.1Very high2 Ų240.2 Ų40.21%0.01319%0.193CC..THydrogen-bonded Turntrans-53.3-43.7173.4-25.530.9000114.1G463 Y465 F526 I575 V579G463-P490 PolarHBondContact N-O 3.22Å; Y465-P490 HydrophobicContact CD1-CB 3.98Å; Y465-P490 HydrophobicContact CD1-CG 3.74Å; Y465-P490 HydrophobicContact CD2-CG 4.23Å; Y465-P490 HydrophobicContact CE1-CG 4.4Å; Y465-P490 HydrophobicContact CG-CB 4.27Å; Y465-P490 HydrophobicContact CG-CG 3.64Å; P490-F526 WeakPolarHBondContact CD-O 3.47Å; P490-F526 HydrophobicContact CG-CD1 4.27Å; P490-F526 HydrophobicContact CG-CE1 4.03Å; P490-I575 HydrophobicContact CB-CG2 4.04Å; P490-V579 HydrophobicContact CB-CG2 3.94Å; P490-V579 HydrophobicContact CG-CG1 3.97Å; P490-V579 HydrophobicContact CG-CG2 4.09Å
491L97.5Very high96.1Very high0 Ų042.5 Ų42.50%021%0.205CC..THydrogen-bonded Turntrans-102.952.4174-64.9-175.9000110.1E462 K489 L493 H494 C527 L528 P529 L554 T572 I575 L576E462-L491 HydrophobicContact CG-CD2 4.06Å; E462-L491 WeakPolarHBondContact OE1-CA 3.29Å; E462-L491 WeakPolarHBondContact OE1-CD2 3.25Å; K489-L491 VanDerWaalsContact C-N 3.29Å; K489-L491 PolarHBondContact O-N 2.89Å; L491-L493 PolarHBondContact O-N 3.21Å; L491-L493 VanDerWaalsContact O-N 3.07Å; L491-H494 HydrophobicContact CB-CB 4.43Å; L491-H494 WeakPolarHBondContact O-CB 3.44Å; L491-H494 PolarHBondContact O-N 2.89Å; L491-H494 VanDerWaalsContact O-N 3.11Å; L491-C527 WeakPolarHBondContact CB-O 3.33Å; L491-C527 PolarHBondContact N-O 3.46Å; L491-L528 HydrophobicContact CB-CD2 3.84Å; L491-L528 HydrophobicContact CB-CG 4.49Å; L491-L528 HydrophobicContact CD1-CD2 3.7Å; L491-L528 HydrophobicContact CD1-CG 4.19Å; L491-L528 HydrophobicContact CG-CD2 4.43Å; L491-P529 WeakPolarHBondContact O-CD 3.25Å; L491-L554 HydrophobicContact CD1-CD2 3.7Å; L491-T572 HydrophobicContact CD1-CG2 3.85Å; L491-T572 HydrophobicContact CD2-CG2 4.03Å; L491-I575 HydrophobicContact CD2-CB 4.08Å; L491-I575 HydrophobicContact CD2-CD1 4.13Å; L491-I575 HydrophobicContact CD2-CG2 3.78Å; L491-I575 HydrophobicContact CG-CG2 4.4Å; L491-L576 HydrophobicContact CD1-CD1 4.07Å; L491-L576 HydrophobicContact CD1-CD2 3.65Å; L491-L576 HydrophobicContact CD1-CG 3.76Å; L491-L576 HydrophobicContact CG-CD2 4.44Å
492S96.7Very high96Very high0 Ų045 Ų450%021%0.211CC..THydrogen-bonded Turntrans-58.4-21.7-173.356.70000114.5L387 Y394 S460 K489L387-S492 WeakPolarHBondContact CD2-O 3.27Å; Y394-S492 VanDerWaalsContact OH-CA 3.3Å; Y394-S492 WeakPolarHBondContact OH-CA 3.26Å; Y394-S492 VanDerWaalsContact OH-CB 3.26Å; Y394-S492 WeakPolarHBondContact OH-CB 3.17Å; Y394-S492 PolarHBondContact OH-O 2.78Å; S460-S492 WeakPolarHBondContact OG-CB 3.27Å; S460-S492 PolarHBondContact OG-OG 2.91Å; K489-S492 WeakPolarHBondContact O-CB 3.39Å; K489-S492 PolarHBondContact O-N 2.8Å; K489-S492 VanDerWaalsContact O-N 3.08Å
493L96.7Very high95.9Very high1 Ų150.6 Ų50.61%0.00524%0.241CC..THydrogen-bonded Turntrans-94.85.8-177.8-56.3177000113.3L387 E462 L491 N547 T548 R669 M673L387-L493 HydrophobicContact CD1-CD2 4.35Å; E462-L493 HydrophobicContact CB-CD1 4.12Å; L491-L493 PolarHBondContact O-N 3.21Å; L491-L493 VanDerWaalsContact O-N 3.07Å; L493-N547 CarbonylContact O-C 3.53Å; L493-N547 WeakPolarHBondContact O-CA 3.47Å; L493-T548 PolarHBondContact O-N 3.42Å; L493-T548 PolarHBondContact O-OG1 3.13Å; L493-R669 VanDerWaalsContact CD2-NH2 3.27Å; L493-M673 HydrophobicContact CD1-CE 3.99Å
494H97.1Very high95.9Very high0 Ų049.8 Ų49.80%023%0.231CC..EExtended strand (participates in β ladder)trans-91.4128177.4-75.574.4000111.3E462 L491 L528 P529 F545E462-H494 IonicContact OE1-CE1 3.92Å; E462-H494 PolarHBondContact OE1-CE1 3.12Å; E462-H494 IonicContact OE1-ND1 3.94Å; E462-H494 PolarHBondContact OE1-ND1 2.98Å; L491-H494 HydrophobicContact CB-CB 4.43Å; L491-H494 WeakPolarHBondContact O-CB 3.44Å; L491-H494 PolarHBondContact O-N 2.89Å; L491-H494 VanDerWaalsContact O-N 3.11Å; H494-L528 HydrophobicContact CB-CD2 3.91Å; H494-P529 VanDerWaalsContact O-CG 3.29Å; H494-P529 WeakPolarHBondContact O-CG 3.37Å; H494-F545 HydrophobicContact CB-CB 4.1Å; H494-F545 HydrophobicContact CB-CD1 4.43Å
495Q95.3Very high95.8Very high18 Ų1847.1 Ų47.18%0.08422%0.224CC..EExtended strand (participates in β ladder)trans-106.7141.3172.2-126.6-160.1-6.700109.8R170 L387 F545 Q546 T548R170-Q495 VanDerWaalsContact NH2-NE2 3.16Å; L387-Q495 HydrophobicContact CD2-CG 4.47Å; Q495-F545 CarbonylContact O-C 3.42Å; Q495-F545 WeakPolarHBondContact O-CA 3.42Å; Q495-Q546 PolarHBondContact N-O 3.42Å; Q495-Q546 PolarHBondContact O-N 3.04Å; Q495-T548 HydrophobicContact CB-CG2 3.93Å; Q495-T548 HydrophobicContact CG-CG2 4.3Å
496R94.6Very high95.7Very high38 Ų3843.1 Ų43.114%0.14321%0.205CC..EExtended strand (participates in β ladder)trans-67144176.6-173.2170.7169.7-168.3-10.4110.8D145 D169 R170 E530 Y544 F545D145-R496 IonicContact OD2-CZ 3.76Å; D145-R496 IonicContact OD2-NH1 2.83Å; D145-R496 PolarHBondContact OD2-NH1 2.85Å; D169-R496 VanDerWaalsContact CB-CZ 3.48Å; D169-R496 IonicContact OD2-NH2 3.78Å; D169-R496 PolarHBondContact OD2-NH2 2.95Å; R170-R496 PolarHBondContact NH1-O 2.84Å; R170-R496 PolarHBondContact NH2-O 3.18Å; R496-E530 HydrophobicContact CB-CB 4.04Å; R496-E530 WeakPolarHBondContact CB-OE2 3.3Å; R496-E530 WeakPolarHBondContact CD-O 2.95Å; R496-E530 PolarHBondContact N-OE2 2.91Å; R496-Y544 CarbonylContact C-O 3.57Å; R496-Y544 WeakPolarHBondContact CA-O 3.08Å; R496-F545 HydrophobicContact CB-CD1 4.1Å; R496-F545 HydrophobicContact CB-CE1 3.98Å; R496-F545 HydrophobicContact CG-CE1 4.38Å
497T94.4Very high95.8Very high24 Ų2442.3 Ų42.315%0.14720%0.202CC..EExtended strand (participates in β ladder)trans-134.6171.9175.260.40000110.3F499 Y544 Q546T497-F499 PolarHBondContact OG1-O 3.12Å; T497-Y544 PolarHBondContact N-O 3.14Å; T497-Q546 HydrophobicContact CG2-CB 3.76Å
498H92.7Very high95.9Very high55 Ų5538.5 Ų38.526%0.25519%0.186SC..SBendtrans-91.2-26.3-179.6-57.8-63.3000113.4D169 R170 E185 Y544D169-H498 PolarHBondContact O-CE1 3.41Å; R170-H498 PolarHBondContact O-CE1 2.82Å; R170-H498 PolarHBondContact O-NE2 3.33Å; E185-H498 HydrophobicContact CG-CB 4.3Å; E185-H498 WeakPolarHBondContact OE1-CB 3.4Å; E185-H498 IonicContact OE1-CG 3.44Å; E185-H498 IonicContact OE2-CD2 2.9Å; E185-H498 IonicContact OE2-CG 2.8Å; H498-Y544 WeakPolarHBondContact O-CD2 3.44Å; H498-Y544 WeakPolarHBondContact O-CE2 3.24Å
499F93.4Very high95.9Very high145 Ų14538.3 Ų38.364%0.63619%0.186SC*.  trans-147.4167-179.462.1-90.8000111.2T497T497-F499 PolarHBondContact OG1-O 3.12Å
500I95.4Very high96Very high12 Ų1237.6 Ų37.66%0.06219%0.185CC..  trans-135.2169.1174.258.2171000109.9M506 Y544 Q553 E555I500-M506 HydrophobicContact CD1-CE 4.3Å; I500-Y544 HydrophobicContact CB-CD1 4.45Å; I500-Y544 HydrophobicContact CD1-CD1 3.83Å; I500-Y544 HydrophobicContact CD1-CE1 3.97Å; I500-Y544 HydrophobicContact CG1-CD1 3.81Å; I500-Y544 HydrophobicContact CG1-CE1 3.97Å; I500-Y544 HydrophobicContact CG2-CD1 3.89Å; I500-Y544 HydrophobicContact CG2-CG 4.11Å; I500-Q553 HydrophobicContact CB-CB 4.42Å; I500-Q553 HydrophobicContact CG2-CB 4.07Å; I500-Q553 HydrophobicContact CG2-CG 4.29Å; I500-E555 HydrophobicContact CD1-CB 3.65Å; I500-E555 HydrophobicContact CD1-CG 4.15Å
501D95.2Very high95.9Very high66 Ų6637.5 Ų37.535%0.35318%0.184SC..  trans-96108174.1177.25.9000109.3D503 R504 M506 Q553D501-D503 VanDerWaalsContact C-N 3.26Å; D501-D503 PolarHBondContact O-N 2.87Å; D501-D503 WeakPolarHBondContact OD1-CB 3.38Å; D501-D503 PolarHBondContact OD1-N 3.49Å; D501-R504 HydrophobicContact CB-CG 4.02Å; D501-R504 IonicContact OD2-NE 2.67Å; D501-M506 VanDerWaalsContact O-CE 3.23Å; D501-M506 WeakPolarHBondContact O-CE 3.49Å; D501-Q553 PolarHBondContact O-OE1 3.31Å
502H92.7Very high95.9Very high111 Ų11139.8 Ų39.851%0.51420%0.198SC..THydrogen-bonded Turntrans-76.5-10.6-178.1-65.2-71.8000113.6R504 E555H502-R504 VanDerWaalsContact C-N 3.25Å; H502-R504 PolarHBondContact O-N 3.18Å; H502-E555 IonicContact CE1-OE1 2.73Å
503D95.1Very high95.9Very high158 Ų15840.9 Ų40.985%0.84521%0.21SC*.THydrogen-bonded Turntrans-81.3-8179-65.4-28.6000112.2D501D501-D503 VanDerWaalsContact C-N 3.26Å; D501-D503 PolarHBondContact O-N 2.87Å; D501-D503 WeakPolarHBondContact OD1-CB 3.38Å; D501-D503 PolarHBondContact OD1-N 3.49Å
504R95.7Very high95.7Very high52 Ų5249.4 Ų49.420%0.19625%0.249CC..SBendtrans-69.2152.3176.1-62.8-169.8178.2-162.11.4112.1D501 H502 M506 D551 D568D501-R504 HydrophobicContact CB-CG 4.02Å; D501-R504 IonicContact OD2-NE 2.67Å; H502-R504 VanDerWaalsContact C-N 3.25Å; H502-R504 PolarHBondContact O-N 3.18Å; R504-M506 HydrophobicContact CB-CE 4.03Å; R504-M506 PolarHBondContact O-N 2.68Å; R504-D551 PolarHBondContact NH1-O 3.22Å; R504-D568 HydrophobicContact CB-CB 4.21Å; R504-D568 WeakPolarHBondContact CD-OD2 3.45Å; R504-D568 IonicContact CZ-OD2 2.96Å; R504-D568 IonicContact NE-OD2 2.99Å; R504-D568 IonicContact NH1-OD2 2.67Å; R504-D568 PolarHBondContact NH1-OD2 2.99Å
505P96.4Very high95.7Very high21 Ų2149.7 Ų49.714%0.13625%0.251CS..  trans-71.187.6177.929.9-35.7000111.4N598 V600 S601 H604P505-N598 HydrophobicContact CB-CB 4.41Å; P505-N598 WeakPolarHBondContact CB-ND2 3.34Å; P505-V600 HydrophobicContact CB-CB 4.42Å; P505-S601 VanDerWaalsContact O-CB 3.26Å; P505-S601 WeakPolarHBondContact O-CB 3.37Å; P505-H604 HydrophobicContact CG-CB 3.66Å
506M96.3Very high95.7Very high31 Ų3150.9 Ų50.915%0.15326%0.261CS..  trans-78.5132.3-177.8-64.1-61.6-179.700112.4I500 D501 R504 K566 D568I500-M506 HydrophobicContact CD1-CE 4.3Å; D501-M506 VanDerWaalsContact O-CE 3.23Å; D501-M506 WeakPolarHBondContact O-CE 3.49Å; R504-M506 HydrophobicContact CB-CE 4.03Å; R504-M506 PolarHBondContact O-N 2.68Å; M506-K566 HydrophobicContact CB-CB 4.28Å; M506-D568 HydrophobicContact SD-CB 4.23Å; M506-D568 PolarHBondContact SD-N 3.29Å; M506-D568 VanDerWaalsContact SD-N 3.44Å
507N97.8Very high95.7Very high0 Ų050.5 Ų50.50%026%0.26CS..EExtended strand (participates in β ladder)trans-89.5138.2162.2-55.2-73000108.7K566 S567 I573 E596 I597 N598 S601N507-K566 CarbonylContact O-C 3.59Å; N507-K566 WeakPolarHBondContact O-CA 3.28Å; N507-S567 WeakPolarHBondContact CB-O 3.45Å; N507-S567 PolarHBondContact N-O 2.96Å; N507-S567 PolarHBondContact ND2-O 3.02Å; N507-S567 VanDerWaalsContact ND2-O 3.08Å; N507-S567 PolarHBondContact O-N 2.93Å; N507-I573 HydrophobicContact CB-CG1 3.99Å; N507-E596 CarbonylContact C-O 3.42Å; N507-E596 WeakPolarHBondContact CA-O 3.24Å; N507-I597 HydrophobicContact CB-CD1 4.13Å; N507-I597 WeakPolarHBondContact OD1-CA 3.2Å; N507-I597 WeakPolarHBondContact OD1-CG2 3.36Å; N507-N598 PolarHBondContact OD1-N 2.96Å; N507-S601 VanDerWaalsContact ND2-CB 3.32Å; N507-S601 WeakPolarHBondContact ND2-CB 3.46Å; N507-S601 PolarHBondContact ND2-OG 3.37Å; N507-S601 PolarHBondContact OD1-OG 3.36Å
508T98Very high95.7Very high25 Ų2551.8 Ų51.815%0.15327%0.274CS..EExtended strand (participates in β ladder)trans-116.2132-176.4-59.20000110.9V564 F565 K566 Y595 E596T508-V564 HydrophobicContact CG2-CG1 3.87Å; T508-F565 CarbonylContact C-O 3.58Å; T508-F565 WeakPolarHBondContact CA-O 3.2Å; T508-K566 HydrophobicContact CG2-CG 4.17Å; T508-Y595 CarbonylContact O-C 3.52Å; T508-Y595 WeakPolarHBondContact O-CA 3.27Å; T508-E596 PolarHBondContact N-O 3.26Å; T508-E596 PolarHBondContact O-N 3.42Å
509L98.3Very high95.8Very high0 Ų051.6 Ų51.60%027%0.273CS..EExtended strand (participates in β ladder)trans-115.3120.3169.4176.870.9000108.9V564 F565 I573 L576 K577 I593L509-V564 WeakPolarHBondContact O-CA 3.29Å; L509-F565 HydrophobicContact CB-CB 4.32Å; L509-F565 HydrophobicContact CD2-CD2 4.4Å; L509-F565 PolarHBondContact N-O 3.46Å; L509-F565 PolarHBondContact O-N 2.92Å; L509-I573 HydrophobicContact CB-CD1 4.21Å; L509-I573 HydrophobicContact CB-CG2 3.75Å; L509-I573 HydrophobicContact CD1-CG2 4.47Å; L509-I573 HydrophobicContact CD2-CG2 4.4Å; L509-I573 HydrophobicContact CG-CG2 4.43Å; L509-L576 HydrophobicContact CD2-CB 3.92Å; L509-K577 HydrophobicContact CD1-CB 4.16Å; L509-K577 HydrophobicContact CD1-CG 4.42Å; L509-K577 HydrophobicContact CD2-CB 4.12Å; L509-I593 HydrophobicContact CD1-CG2 3.59Å
510T98.3Very high96Very high31 Ų3144.7 Ų44.719%0.1924%0.243CC..EExtended strand (participates in β ladder)trans-116121.5178.9-58.10000110.1T512 G563 V564 S594T510-T512 HydrophobicContact CG2-CG2 4.25Å; T510-G563 CarbonylContact C-O 3.49Å; T510-G563 WeakPolarHBondContact CA-O 3.41Å; T510-V564 HydrophobicContact CG2-CG2 4.24Å; T510-S594 WeakPolarHBondContact CB-OG 3.25Å; T510-S594 PolarHBondContact N-O 3.1Å; T510-S594 PolarHBondContact O-N 2.97Å; T510-S594 PolarHBondContact O-OG 3.49Å
511L97.3Very high96.1Very high0 Ų044.2 Ų44.20%024%0.24CC..EExtended strand (participates in β ladder)trans-105.1126.3174.9-57.2179.4000109.1E562 G563 F565 L580 L591 I593L511-E562 CarbonylContact O-C 3.58Å; L511-E562 WeakPolarHBondContact O-CA 3.29Å; L511-G563 PolarHBondContact N-O 3.38Å; L511-G563 PolarHBondContact O-N 2.85Å; L511-F565 HydrophobicContact CD1-CE2 3.82Å; L511-F565 HydrophobicContact CG-CE2 4.34Å; L511-L580 HydrophobicContact CD1-CB 3.89Å; L511-L580 HydrophobicContact CD1-CD1 3.49Å; L511-L580 VanDerWaalsContact CD1-CD1 3.49Å; L511-L580 HydrophobicContact CD1-CG 4.23Å; L511-L591 HydrophobicContact CD2-CD1 4.45Å; L511-I593 HydrophobicContact CD2-CB 4.06Å; L511-I593 HydrophobicContact CD2-CD1 3.82Å; L511-I593 HydrophobicContact CD2-CG1 3.54Å; L511-I593 HydrophobicContact CD2-CG2 3.79Å
512T97.3Very high96.1Very high48 Ų4842.9 Ų42.929%0.29424%0.236SC..EExtended strand (participates in β ladder)trans-126.9140.9172.4530000110T510 G561 E562 N592T510-T512 HydrophobicContact CG2-CG2 4.25Å; T512-G561 WeakPolarHBondContact CA-O 3.44Å; T512-E562 HydrophobicContact CG2-CG 4.45Å; T512-N592 PolarHBondContact N-O 2.8Å; T512-N592 PolarHBondContact O-N 3.24Å; T512-N592 WeakPolarHBondContact OG1-CB 3.36Å; T512-N592 PolarHBondContact OG1-O 3.31Å
513G95Very high96.3Very high23 Ų2337.6 Ų37.624%0.23721%0.212CC..EExtended strand (participates in β ladder)trans173.6-176.6-178.100000114.2F515 G561G513-F515 PolarHBondContact O-N 2.74Å; G513-G561 PolarHBondContact N-O 2.97Å; G513-G561 VanDerWaalsContact N-O 3.11Å; G513-G561 VanDerWaalsContact O-CA 3.23Å; G513-G561 WeakPolarHBondContact O-CA 3.36Å
514Q94.4Very high96.4Very high179 Ų17930.1 Ų30.184%0.83617%0.172SC*.SBendtrans-9173.3178.8-64-65.2-20.600110.2
515F95.8Very high96.5Very high7 Ų728.8 Ų28.83%0.03117%0.169CC..  trans-128.4146.4173.655.6-97.2000111.4G513 E519 V520 W523 G561 E562 I589 L591G513-F515 PolarHBondContact O-N 2.74Å; F515-E519 HydrophobicContact CB-CB 4.33Å; F515-V520 HydrophobicContact CD2-CB 3.64Å; F515-V520 HydrophobicContact CD2-CG1 3.94Å; F515-V520 HydrophobicContact CD2-CG2 4.47Å; F515-V520 HydrophobicContact CE2-CB 3.6Å; F515-V520 HydrophobicContact CE2-CG1 3.85Å; F515-V520 HydrophobicContact CE2-CG2 3.99Å; F515-W523 HydrophobicContact CB-CH2 3.87Å; F515-W523 HydrophobicContact CB-CZ3 4.34Å; F515-W523 HydrophobicContact CD1-CH2 4.09Å; F515-W523 HydrophobicContact CD1-CZ3 4.02Å; F515-W523 HydrophobicContact CD2-CZ3 4.47Å; F515-W523 HydrophobicContact CE1-CZ3 4.43Å; F515-W523 HydrophobicContact CG-CH2 4.03Å; F515-W523 HydrophobicContact CG-CZ3 4.03Å; F515-G561 PolarHBondContact O-N 2.8Å; F515-E562 VanDerWaalsContact CZ-N 3.28Å; F515-I589 HydrophobicContact CB-CD1 4.26Å; F515-I589 HydrophobicContact CB-CG2 4.37Å; F515-L591 HydrophobicContact CD1-CD2 3.53Å; F515-L591 HydrophobicContact CE1-CD2 3.56Å
516S95.1Very high96.5Very high43 Ų4330.8 Ų30.830%0.30118%0.176SC..  trans-75161.3172.965.70000111.7A518 E519 V520S516-A518 VanDerWaalsContact C-N 3.28Å; S516-A518 PolarHBondContact O-N 3.35Å; S516-E519 WeakPolarHBondContact CB-OE2 3.44Å; S516-E519 PolarHBondContact N-OE2 3.44Å; S516-E519 PolarHBondContact O-N 3.38Å; S516-E519 WeakPolarHBondContact OG-CB 3.32Å; S516-E519 VanDerWaalsContact OG-CD 3.28Å; S516-E519 VanDerWaalsContact OG-CG 3.22Å; S516-E519 WeakPolarHBondContact OG-CG 3.49Å; S516-E519 PolarHBondContact OG-N 3.17Å; S516-E519 PolarHBondContact OG-OE2 3.45Å; S516-V520 PolarHBondContact O-N 3.3Å
517F95.6Very high96.6Very high29 Ų2929.3 Ų29.313%0.12717%0.169CC..Hα-helixtrans-58-40.6174176.8-110.1000112.3E519 V520 H521 P535 P536 V541 Y558F517-E519 VanDerWaalsContact C-N 3.34Å; F517-E519 PolarHBondContact O-N 3.21Å; F517-V520 VanDerWaalsContact O-CG1 3.25Å; F517-V520 WeakPolarHBondContact O-CG1 3.33Å; F517-H521 VanDerWaalsContact O-CB 3.23Å; F517-H521 WeakPolarHBondContact O-CB 3.38Å; F517-H521 PolarHBondContact O-N 2.95Å; F517-P535 HydrophobicContact CD1-CB 4.32Å; F517-P535 HydrophobicContact CE1-CB 3.9Å; F517-P536 WeakPolarHBondContact CE1-O 3.48Å; F517-V541 HydrophobicContact CE2-CB 4.35Å; F517-V541 HydrophobicContact CE2-CG2 4.03Å; F517-V541 HydrophobicContact CZ-CB 4.31Å; F517-V541 HydrophobicContact CZ-CG2 3.58Å; F517-Y558 HydrophobicContact CD2-CD2 4.23Å; F517-Y558 HydrophobicContact CD2-CE2 4.38Å; F517-Y558 AromaticContact CE2-CD2 3.82Å; F517-Y558 HydrophobicContact CE2-CD2 3.82Å; F517-Y558 AromaticContact CE2-CE2 3.65Å; F517-Y558 HydrophobicContact CE2-CE2 3.65Å; F517-Y558 HydrophobicContact CZ-CE2 4.2Å
518A94.6Very high96.6Very high52 Ų5229.5 Ų29.543%0.4317%0.169SC..Hα-helixtrans-65.7-34.5177.900000112.9S516 S522 P535S516-A518 VanDerWaalsContact C-N 3.28Å; S516-A518 PolarHBondContact O-N 3.35Å; A518-S522 WeakPolarHBondContact O-CB 3.38Å; A518-S522 PolarHBondContact O-N 3.14Å; A518-P535 HydrophobicContact CB-CG 4.29Å
519E95.3Very high96.4Very high50 Ų5029 Ų2923%0.23417%0.167CC..Hα-helixtrans-67.8-52.2177.6-76.6165139.500111.8F515 S516 F517 H521 S522 W523F515-E519 HydrophobicContact CB-CB 4.33Å; S516-E519 WeakPolarHBondContact CB-OE2 3.44Å; S516-E519 PolarHBondContact N-OE2 3.44Å; S516-E519 PolarHBondContact O-N 3.38Å; S516-E519 WeakPolarHBondContact OG-CB 3.32Å; S516-E519 VanDerWaalsContact OG-CD 3.28Å; S516-E519 VanDerWaalsContact OG-CG 3.22Å; S516-E519 WeakPolarHBondContact OG-CG 3.49Å; S516-E519 PolarHBondContact OG-N 3.17Å; S516-E519 PolarHBondContact OG-OE2 3.45Å; F517-E519 VanDerWaalsContact C-N 3.34Å; F517-E519 PolarHBondContact O-N 3.21Å; E519-H521 VanDerWaalsContact C-N 3.28Å; E519-H521 PolarHBondContact O-N 3.38Å; E519-S522 PolarHBondContact O-N 2.81Å; E519-S522 VanDerWaalsContact O-N 3.11Å; E519-S522 PolarHBondContact O-OG 2.91Å; E519-W523 HydrophobicContact CB-CZ2 4.48Å; E519-W523 VanDerWaalsContact O-CG 3.3Å; E519-W523 PolarHBondContact O-N 3.24Å
520V96.6Very high96.2Very high1 Ų132.3 Ų32.31%0.00618%0.182CC..Hα-helixtrans-61.9-39.1177.161.90000111.4F515 S516 F517 S522 W523 V524 Y558F515-V520 HydrophobicContact CD2-CB 3.64Å; F515-V520 HydrophobicContact CD2-CG1 3.94Å; F515-V520 HydrophobicContact CD2-CG2 4.47Å; F515-V520 HydrophobicContact CE2-CB 3.6Å; F515-V520 HydrophobicContact CE2-CG1 3.85Å; F515-V520 HydrophobicContact CE2-CG2 3.99Å; S516-V520 PolarHBondContact O-N 3.3Å; F517-V520 VanDerWaalsContact O-CG1 3.25Å; F517-V520 WeakPolarHBondContact O-CG1 3.33Å; V520-S522 VanDerWaalsContact C-N 3.34Å; V520-S522 PolarHBondContact O-N 2.94Å; V520-W523 HydrophobicContact CB-CE3 4.21Å; V520-W523 HydrophobicContact CG2-CE3 4.27Å; V520-W523 WeakPolarHBondContact O-CB 3.44Å; V520-W523 PolarHBondContact O-N 2.95Å; V520-W523 VanDerWaalsContact O-N 3.15Å; V520-V524 WeakPolarHBondContact O-CG2 3.39Å; V520-V524 PolarHBondContact O-N 3.21Å; V520-Y558 HydrophobicContact CG1-CD2 3.74Å; V520-Y558 HydrophobicContact CG1-CG 4.41Å; V520-Y558 HydrophobicContact CG2-CD2 4.26Å; V520-Y558 HydrophobicContact CG2-CG 4.2Å
521H96.9Very high96Very high2 Ų231.7 Ų31.71%0.00918%0.178CC..Hα-helixtrans-60.1-43.8174.3-17872.6000111.6F517 E519 W523 V524 V525 P532 P536 Y558F517-H521 VanDerWaalsContact O-CB 3.23Å; F517-H521 WeakPolarHBondContact O-CB 3.38Å; F517-H521 PolarHBondContact O-N 2.95Å; E519-H521 VanDerWaalsContact C-N 3.28Å; E519-H521 PolarHBondContact O-N 3.38Å; H521-W523 VanDerWaalsContact C-N 3.26Å; H521-W523 PolarHBondContact O-N 3.44Å; H521-V524 PolarHBondContact O-N 3.39Å; H521-V524 VanDerWaalsContact O-N 3.13Å; H521-V525 WeakPolarHBondContact O-CG2 3.36Å; H521-V525 PolarHBondContact O-N 3.07Å; H521-P532 PolarHBondContact CE1-O 3.45Å; H521-P532 PolarHBondContact NE2-O 3.17Å; H521-P536 VanDerWaalsContact CE1-CD 3.44Å; H521-P536 WeakPolarHBondContact CE1-CD 3.44Å; H521-Y558 HydrophobicContact CB-CE2 4.02Å; H521-Y558 AromaticContact ND1-CE2 3.97Å; H521-Y558 AromaticContact ND1-CZ 3.84Å; H521-Y558 PolarHBondContact ND1-OH 3.05Å
522S96.5Very high95.8Very high37 Ų3732 Ų3226%0.25918%0.181SC..Hα-helixtrans-62.3-33.1176.476.20000113.1A518 E519 V520 F526 R587A518-S522 WeakPolarHBondContact O-CB 3.38Å; A518-S522 PolarHBondContact O-N 3.14Å; E519-S522 PolarHBondContact O-N 2.81Å; E519-S522 VanDerWaalsContact O-N 3.11Å; E519-S522 PolarHBondContact O-OG 2.91Å; V520-S522 VanDerWaalsContact C-N 3.34Å; V520-S522 PolarHBondContact O-N 2.94Å; S522-F526 WeakPolarHBondContact O-CB 3.32Å; S522-F526 PolarHBondContact O-N 3.21Å; S522-R587 PolarHBondContact OG-NH2 2.86Å
523W96.9Very high95.5Very high1 Ų136.7 Ų36.70%0.00420%0.199CC..Hα-helixtrans-69.6-41.5173.6-55.1-23.9000111.6F515 E519 V520 H521 F526 C527 L580 E583 A584 I589 L591F515-W523 HydrophobicContact CB-CH2 3.87Å; F515-W523 HydrophobicContact CB-CZ3 4.34Å; F515-W523 HydrophobicContact CD1-CH2 4.09Å; F515-W523 HydrophobicContact CD1-CZ3 4.02Å; F515-W523 HydrophobicContact CD2-CZ3 4.47Å; F515-W523 HydrophobicContact CE1-CZ3 4.43Å; F515-W523 HydrophobicContact CG-CH2 4.03Å; F515-W523 HydrophobicContact CG-CZ3 4.03Å; E519-W523 HydrophobicContact CB-CZ2 4.48Å; E519-W523 VanDerWaalsContact O-CG 3.3Å; E519-W523 PolarHBondContact O-N 3.24Å; V520-W523 HydrophobicContact CB-CE3 4.21Å; V520-W523 HydrophobicContact CG2-CE3 4.27Å; V520-W523 WeakPolarHBondContact O-CB 3.44Å; V520-W523 PolarHBondContact O-N 2.95Å; V520-W523 VanDerWaalsContact O-N 3.15Å; H521-W523 VanDerWaalsContact C-N 3.26Å; H521-W523 PolarHBondContact O-N 3.44Å; W523-F526 WeakPolarHBondContact O-CB 3.28Å; W523-F526 PolarHBondContact O-N 2.84Å; W523-F526 VanDerWaalsContact O-N 3.16Å; W523-C527 WeakPolarHBondContact O-CB 3.49Å; W523-C527 PolarHBondContact O-N 2.99Å; W523-C527 PolarHBondContact O-SG 3.2Å; W523-L580 HydrophobicContact CB-CD2 3.61Å; W523-L580 HydrophobicContact CG-CD2 4.46Å; W523-E583 HydrophobicContact CG-CB 4.13Å; W523-A584 HydrophobicContact CH2-CB 4.05Å; W523-A584 HydrophobicContact CZ2-CB 4.17Å; W523-I589 HydrophobicContact CH2-CD1 4.04Å; W523-I589 HydrophobicContact CH2-CG2 4.24Å; W523-I589 HydrophobicContact CZ2-CD1 3.68Å; W523-L591 HydrophobicContact CH2-CD2 4.21Å; W523-L591 HydrophobicContact CZ3-CD1 4.3Å; W523-L591 HydrophobicContact CZ3-CD2 4.19Å
524V97.4Very high95.3Very high1 Ų140.3 Ų40.31%0.00621%0.208CC..Hα-helixtrans-62.6-45175.3173.80000110.9V520 H521 F526 C527 L528 V531 Y558 F565V520-V524 WeakPolarHBondContact O-CG2 3.39Å; V520-V524 PolarHBondContact O-N 3.21Å; H521-V524 PolarHBondContact O-N 3.39Å; H521-V524 VanDerWaalsContact O-N 3.13Å; V524-F526 PolarHBondContact O-N 3.32Å; V524-C527 PolarHBondContact O-N 2.93Å; V524-C527 VanDerWaalsContact O-N 3.1Å; V524-L528 HydrophobicContact CG1-CD1 4Å; V524-L528 PolarHBondContact O-N 2.88Å; V524-V531 HydrophobicContact CG1-CG1 4.37Å; V524-V531 HydrophobicContact CG1-CG2 4.22Å; V524-Y558 HydrophobicContact CB-CE1 4.32Å; V524-Y558 HydrophobicContact CG1-CE1 4.01Å; V524-Y558 HydrophobicContact CG2-CD1 3.98Å; V524-Y558 HydrophobicContact CG2-CE1 3.87Å; V524-Y558 HydrophobicContact CG2-CG 4.5Å; V524-F565 HydrophobicContact CG2-CE1 4.05Å; V524-F565 HydrophobicContact CG2-CZ 4.12Å
525V97.1Very high95Very high24 Ų2434.2 Ų34.215%0.14518%0.184CC..Hα-helixtrans-60.1-33.8173.4171.60000112K489 H521 V531 P532 E533K489-V525 PolarHBondContact NZ-O 3.49Å; H521-V525 WeakPolarHBondContact O-CG2 3.36Å; H521-V525 PolarHBondContact O-N 3.07Å; V525-V531 HydrophobicContact CG2-CB 4.06Å; V525-V531 HydrophobicContact CG2-CG1 3.54Å; V525-P532 WeakPolarHBondContact CG2-O 3.5Å; V525-E533 HydrophobicContact CG1-CG 4.45Å
526F97.2Very high94.6Very high62 Ų6235 Ų3527%0.27219%0.19SC..Hα-helixtrans-70.3-40.7174.4-177.6-94000111.8Y465 K489 P490 S522 W523 V524 V579 E583Y465-F526 AromaticContact CD2-CE1 3.89Å; Y465-F526 HydrophobicContact CD2-CE1 3.89Å; Y465-F526 AromaticContact CD2-CZ 3.66Å; Y465-F526 HydrophobicContact CD2-CZ 3.66Å; Y465-F526 AromaticContact CE2-CE1 3.77Å; Y465-F526 HydrophobicContact CE2-CE1 3.77Å; Y465-F526 AromaticContact CE2-CZ 3.64Å; Y465-F526 HydrophobicContact CE2-CZ 3.64Å; K489-F526 WeakPolarHBondContact CD-O 3.22Å; P490-F526 WeakPolarHBondContact CD-O 3.47Å; P490-F526 HydrophobicContact CG-CD1 4.27Å; P490-F526 HydrophobicContact CG-CE1 4.03Å; S522-F526 WeakPolarHBondContact O-CB 3.32Å; S522-F526 PolarHBondContact O-N 3.21Å; W523-F526 WeakPolarHBondContact O-CB 3.28Å; W523-F526 PolarHBondContact O-N 2.84Å; W523-F526 VanDerWaalsContact O-N 3.16Å; V524-F526 PolarHBondContact O-N 3.32Å; F526-V579 HydrophobicContact CD1-CG1 3.97Å; F526-V579 HydrophobicContact CE1-CG1 3.87Å; F526-E583 HydrophobicContact CD1-CG 4.2Å
527C97.5Very high94.1Very high1 Ų137.7 Ų37.71%0.00722%0.215CC..Hα-helixtrans-77.9-37.1-175.6-71.80000114.5L491 W523 V524 L576 V579L491-C527 WeakPolarHBondContact CB-O 3.33Å; L491-C527 PolarHBondContact N-O 3.46Å; W523-C527 WeakPolarHBondContact O-CB 3.49Å; W523-C527 PolarHBondContact O-N 2.99Å; W523-C527 PolarHBondContact O-SG 3.2Å; V524-C527 PolarHBondContact O-N 2.93Å; V524-C527 VanDerWaalsContact O-N 3.1Å; C527-L576 HydrophobicContact CB-CD2 4.09Å; C527-V579 VanDerWaalsContact SG-CG1 3.53Å
528L96.8Very high93.6Very high3 Ų338.9 Ų38.92%0.01624%0.235CC..SBendtrans-119.5142-165.2-76.7155.1000112.6L491 H494 V524 V531 F545 L554L491-L528 HydrophobicContact CB-CD2 3.84Å; L491-L528 HydrophobicContact CB-CG 4.49Å; L491-L528 HydrophobicContact CD1-CD2 3.7Å; L491-L528 HydrophobicContact CD1-CG 4.19Å; L491-L528 HydrophobicContact CG-CD2 4.43Å; H494-L528 HydrophobicContact CB-CD2 3.91Å; V524-L528 HydrophobicContact CG1-CD1 4Å; V524-L528 PolarHBondContact O-N 2.88Å; L528-V531 HydrophobicContact CB-CG2 3.94Å; L528-F545 HydrophobicContact CB-CE1 4.21Å; L528-F545 HydrophobicContact CB-CZ 4.06Å; L528-F545 HydrophobicContact CD1-CD2 4.18Å; L528-F545 HydrophobicContact CD1-CE2 3.65Å; L528-F545 HydrophobicContact CD1-CZ 3.93Å; L528-F545 HydrophobicContact CD2-CD1 4.11Å; L528-F545 HydrophobicContact CD2-CD2 4.12Å; L528-F545 HydrophobicContact CD2-CE1 4.22Å; L528-F545 HydrophobicContact CD2-CE2 4.21Å; L528-F545 HydrophobicContact CD2-CG 4.08Å; L528-F545 HydrophobicContact CD2-CZ 4.27Å; L528-F545 HydrophobicContact CG-CE2 4.36Å; L528-F545 HydrophobicContact CG-CZ 4.31Å; L528-L554 HydrophobicContact CD1-CD2 4.15Å; L528-L554 HydrophobicContact CD2-CD2 3.77Å
529P94.6Very high93.1Very high15 Ų1544.2 Ų44.210%0.09725%0.251CS..THydrogen-bonded Turntrans-66.3162.7166.7-19.933.9000112.3K489 L491 H494 V531 F545K489-P529 HydrophobicContact CB-CG 4.33Å; K489-P529 HydrophobicContact CG-CG 4.31Å; L491-P529 WeakPolarHBondContact O-CD 3.25Å; H494-P529 VanDerWaalsContact O-CG 3.29Å; H494-P529 WeakPolarHBondContact O-CG 3.37Å; P529-V531 PolarHBondContact O-N 2.89Å; P529-V531 VanDerWaalsContact O-N 3.08Å; P529-F545 WeakPolarHBondContact O-CE1 3.47Å
530E93.4Very high93Very high70 Ų7044.6 Ų44.633%0.32726%0.259SS..THydrogen-bonded Turntrans56.827.8168.4-56.5-177.1170.500115.8R170 R496R170-E530 IonicContact CZ-OE2 3.24Å; R170-E530 IonicContact NE-OE2 3.31Å; R170-E530 IonicContact NH2-OE1 3.92Å; R170-E530 IonicContact NH2-OE2 3.42Å; R170-E530 PolarHBondContact NH2-OE2 3.23Å; R496-E530 HydrophobicContact CB-CB 4.04Å; R496-E530 WeakPolarHBondContact CB-OE2 3.3Å; R496-E530 WeakPolarHBondContact CD-O 2.95Å; R496-E530 PolarHBondContact N-OE2 2.91Å
531V95.1Very high93Very high18 Ų1845.4 Ų45.411%0.10926%0.264CS..  trans-100.3129.5169-175.20000108.7V524 V525 L528 P529 F543 F545V524-V531 HydrophobicContact CG1-CG1 4.37Å; V524-V531 HydrophobicContact CG1-CG2 4.22Å; V525-V531 HydrophobicContact CG2-CB 4.06Å; V525-V531 HydrophobicContact CG2-CG1 3.54Å; L528-V531 HydrophobicContact CB-CG2 3.94Å; P529-V531 PolarHBondContact O-N 2.89Å; P529-V531 VanDerWaalsContact O-N 3.08Å; V531-F543 HydrophobicContact CG1-CD2 4.28Å; V531-F543 HydrophobicContact CG1-CE2 3.61Å; V531-F543 HydrophobicContact CG1-CZ 4.21Å; V531-F543 HydrophobicContact CG2-CD2 4.45Å; V531-F545 HydrophobicContact CG2-CE1 4.21Å; V531-F545 HydrophobicContact CG2-CZ 3.72Å
532P93.5Very high92.9Very high7 Ų748 Ų485%0.04528%0.28CS..  trans-61.2139.7176.725.5-34.1000110.2Y127 H521 V525 K534 P536 F543Y127-P532 HydrophobicContact CE1-CB 4.26Å; H521-P532 PolarHBondContact CE1-O 3.45Å; H521-P532 PolarHBondContact NE2-O 3.17Å; V525-P532 WeakPolarHBondContact CG2-O 3.5Å; P532-K534 VanDerWaalsContact C-N 3.25Å; P532-K534 PolarHBondContact O-N 2.88Å; P532-P536 HydrophobicContact CG-CG 4.5Å; P532-F543 HydrophobicContact CG-CZ 4.38Å
533E90.7Very high93Very high146 Ų14646.8 Ų46.868%0.68227%0.27SS*.SBendtrans-67.7-29.5179.4-69175.5179.300112.5V525V525-E533 HydrophobicContact CG1-CG 4.45Å
534K90.2Very high93Very high98 Ų9849.5 Ų49.543%0.42628%0.281SS..SBendtrans-81.4126.2178.2-173.4175.1179.3176.30108.5P532 P536P532-K534 VanDerWaalsContact C-N 3.25Å; P532-K534 PolarHBondContact O-N 2.88Å; K534-P536 WeakPolarHBondContact O-CD 3.5Å
535P89.1Confident93Very high52 Ų5249.5 Ų49.534%0.33828%0.28SS..PPolyproline II helixtrans-54.1126.4173.3-24.232.3000110.6F517 A518F517-P535 HydrophobicContact CD1-CB 4.32Å; F517-P535 HydrophobicContact CE1-CB 3.9Å; A518-P535 HydrophobicContact CB-CG 4.29Å
536P87.8Confident93Very high22 Ų2250.2 Ų50.214%0.14328%0.282CS..PPolyproline II helixtrans-57.7153.8175.5-25.634.4000111.5F517 H521 P532 K534 V541 F543F517-P536 WeakPolarHBondContact CE1-O 3.48Å; H521-P536 VanDerWaalsContact CE1-CD 3.44Å; H521-P536 WeakPolarHBondContact CE1-CD 3.44Å; P532-P536 HydrophobicContact CG-CG 4.5Å; K534-P536 WeakPolarHBondContact O-CD 3.5Å; P536-V541 HydrophobicContact CB-CG2 3.74Å; P536-V541 HydrophobicContact CG-CG1 4.38Å; P536-V541 HydrophobicContact CG-CG2 3.85Å; P536-F543 HydrophobicContact CG-CZ 4.19Å
537A82.6Confident93Very high100 Ų10047.3 Ų47.383%0.82627%0.27SS*.SBendtrans-66.8135.2174.700000110.5
538G85.1Confident92.8Very high54 Ų5447.8 Ų47.856%0.55727%0.273SS*.SBendtrans122.3-178.6-178.100000112.8
539E85.7Confident92.6Very high164 Ų16448.7 Ų48.777%0.76628%0.276SS*.SBendtrans-106.3-9.7179.5-61-166154.400113.4R559E539-R559 VanDerWaalsContact O-CA 3.23Å; E539-R559 WeakPolarHBondContact O-CA 3.41Å; E539-R559 WeakPolarHBondContact O-CB 3.48Å
540C93.5Very high92.5Very high59 Ų5948.2 Ų48.240%0.39927%0.273SS..EExtended strand (participates in β ladder)trans-144.1139.9-176.9-172.30000109.7Y558 R559C540-Y558 WeakPolarHBondContact CA-O 3.47Å; C540-R559 HydrophobicContact CB-CB 4.02Å
541V95.3Very high92.5Very high17 Ų1747.5 Ų47.510%0.10327%0.272CS..EExtended strand (participates in β ladder)trans-135.6145.3177.9169.50000109.7F517 P536 F543 I557 Y558F517-V541 HydrophobicContact CE2-CB 4.35Å; F517-V541 HydrophobicContact CE2-CG2 4.03Å; F517-V541 HydrophobicContact CZ-CB 4.31Å; F517-V541 HydrophobicContact CZ-CG2 3.58Å; P536-V541 HydrophobicContact CB-CG2 3.74Å; P536-V541 HydrophobicContact CG-CG1 4.38Å; P536-V541 HydrophobicContact CG-CG2 3.85Å; V541-F543 HydrophobicContact CG1-CD1 4.26Å; V541-F543 HydrophobicContact CG1-CD2 3.9Å; V541-F543 HydrophobicContact CG1-CE1 3.93Å; V541-F543 HydrophobicContact CG1-CE2 3.56Å; V541-F543 HydrophobicContact CG1-CG 4.24Å; V541-F543 HydrophobicContact CG1-CZ 3.57Å; V541-I557 WeakPolarHBondContact O-CA 3.46Å; V541-Y558 HydrophobicContact CB-CE1 4.46Å; V541-Y558 HydrophobicContact CB-CE2 4.14Å; V541-Y558 HydrophobicContact CG1-CE1 4.34Å; V541-Y558 PolarHBondContact N-O 2.78Å; V541-Y558 PolarHBondContact O-N 3.31Å
542T96.2Very high92.5Very high58 Ų5846.7 Ų46.736%0.35627%0.266SS..EExtended strand (participates in β ladder)trans-121.9130.7171.7-55.50000109.5Y544 E555 S556 I557T542-Y544 HydrophobicContact CG2-CD1 4.37Å; T542-Y544 HydrophobicContact CG2-CE1 3.68Å; T542-Y544 HydrophobicContact CG2-CE2 4.25Å; T542-E555 HydrophobicContact CG2-CG 4.49Å; T542-S556 CarbonylContact C-O 3.59Å; T542-S556 VanDerWaalsContact CA-O 3.29Å; T542-S556 WeakPolarHBondContact CA-O 3.27Å; T542-I557 HydrophobicContact CG2-CG1 3.7Å
543F96.9Very high92.7Very high11 Ų1147.2 Ų47.25%0.04827%0.268CS..EExtended strand (participates in β ladder)trans-125.1144.2169.9-67.1-51.6000110.7V531 P532 P536 V541 F545 S556 Y558V531-F543 HydrophobicContact CG1-CD2 4.28Å; V531-F543 HydrophobicContact CG1-CE2 3.61Å; V531-F543 HydrophobicContact CG1-CZ 4.21Å; V531-F543 HydrophobicContact CG2-CD2 4.45Å; P532-F543 HydrophobicContact CG-CZ 4.38Å; P536-F543 HydrophobicContact CG-CZ 4.19Å; V541-F543 HydrophobicContact CG1-CD1 4.26Å; V541-F543 HydrophobicContact CG1-CD2 3.9Å; V541-F543 HydrophobicContact CG1-CE1 3.93Å; V541-F543 HydrophobicContact CG1-CE2 3.56Å; V541-F543 HydrophobicContact CG1-CG 4.24Å; V541-F543 HydrophobicContact CG1-CZ 3.57Å; F543-F545 HydrophobicContact CB-CD2 4.34Å; F543-F545 HydrophobicContact CB-CE2 3.41Å; F543-F545 VanDerWaalsContact CB-CE2 3.41Å; F543-F545 HydrophobicContact CB-CZ 3.76Å; F543-F545 HydrophobicContact CG-CE2 4.42Å; F543-F545 HydrophobicContact CG-CZ 4.36Å; F543-S556 PolarHBondContact N-O 3.15Å; F543-S556 PolarHBondContact O-N 3.23Å; F543-Y558 HydrophobicContact CD2-CE1 4.06Å; F543-Y558 HydrophobicContact CE2-CE1 4.4Å; F543-Y558 WeakPolarHBondContact CE2-OH 3.19Å
544Y97.8Very high93.1Very high58 Ų5840.2 Ų40.223%0.22724%0.236CC..EExtended strand (participates in β ladder)trans-114.7138.9176.5-59.4-56.7000109.7R496 T497 H498 I500 T542 L554 E555R496-Y544 CarbonylContact C-O 3.57Å; R496-Y544 WeakPolarHBondContact CA-O 3.08Å; T497-Y544 PolarHBondContact N-O 3.14Å; H498-Y544 WeakPolarHBondContact O-CD2 3.44Å; H498-Y544 WeakPolarHBondContact O-CE2 3.24Å; I500-Y544 HydrophobicContact CB-CD1 4.45Å; I500-Y544 HydrophobicContact CD1-CD1 3.83Å; I500-Y544 HydrophobicContact CD1-CE1 3.97Å; I500-Y544 HydrophobicContact CG1-CD1 3.81Å; I500-Y544 HydrophobicContact CG1-CE1 3.97Å; I500-Y544 HydrophobicContact CG2-CD1 3.89Å; I500-Y544 HydrophobicContact CG2-CG 4.11Å; T542-Y544 HydrophobicContact CG2-CD1 4.37Å; T542-Y544 HydrophobicContact CG2-CE1 3.68Å; T542-Y544 HydrophobicContact CG2-CE2 4.25Å; Y544-L554 CarbonylContact C-O 3.51Å; Y544-E555 HydrophobicContact CD1-CB 4.38Å; Y544-E555 HydrophobicContact CD1-CG 4.11Å; Y544-E555 HydrophobicContact CE1-CG 3.81Å
545F97.6Very high93.5Very high0 Ų036.1 Ų36.10%022%0.218CC..EExtended strand (participates in β ladder)trans-136.2153.8178.2-56.7-92.1000111.3H494 Q495 R496 L528 P529 V531 F543 Q553 L554H494-F545 HydrophobicContact CB-CB 4.1Å; H494-F545 HydrophobicContact CB-CD1 4.43Å; Q495-F545 CarbonylContact O-C 3.42Å; Q495-F545 WeakPolarHBondContact O-CA 3.42Å; R496-F545 HydrophobicContact CB-CD1 4.1Å; R496-F545 HydrophobicContact CB-CE1 3.98Å; R496-F545 HydrophobicContact CG-CE1 4.38Å; L528-F545 HydrophobicContact CB-CE1 4.21Å; L528-F545 HydrophobicContact CB-CZ 4.06Å; L528-F545 HydrophobicContact CD1-CD2 4.18Å; L528-F545 HydrophobicContact CD1-CE2 3.65Å; L528-F545 HydrophobicContact CD1-CZ 3.93Å; L528-F545 HydrophobicContact CD2-CD1 4.11Å; L528-F545 HydrophobicContact CD2-CD2 4.12Å; L528-F545 HydrophobicContact CD2-CE1 4.22Å; L528-F545 HydrophobicContact CD2-CE2 4.21Å; L528-F545 HydrophobicContact CD2-CG 4.08Å; L528-F545 HydrophobicContact CD2-CZ 4.27Å; L528-F545 HydrophobicContact CG-CE2 4.36Å; L528-F545 HydrophobicContact CG-CZ 4.31Å; P529-F545 WeakPolarHBondContact O-CE1 3.47Å; V531-F545 HydrophobicContact CG2-CE1 4.21Å; V531-F545 HydrophobicContact CG2-CZ 3.72Å; F543-F545 HydrophobicContact CB-CD2 4.34Å; F543-F545 HydrophobicContact CB-CE2 3.41Å; F543-F545 VanDerWaalsContact CB-CE2 3.41Å; F543-F545 HydrophobicContact CB-CZ 3.76Å; F543-F545 HydrophobicContact CG-CE2 4.42Å; F543-F545 HydrophobicContact CG-CZ 4.36Å; F545-Q553 WeakPolarHBondContact O-CA 3.31Å; F545-L554 HydrophobicContact CB-CB 4.24Å; F545-L554 HydrophobicContact CD2-CD2 4.26Å; F545-L554 HydrophobicContact CD2-CG 4.44Å; F545-L554 PolarHBondContact N-O 2.6Å; F545-L554 PolarHBondContact O-N 3.09Å
546Q96.8Very high93.9Very high40 Ų4033.6 Ų33.619%0.18720%0.202CC..EExtended strand (participates in β ladder)trans-127.3131.9171.2-174.9178.98.800109.2Q495 T497 T548 D551 T552Q495-Q546 PolarHBondContact N-O 3.42Å; Q495-Q546 PolarHBondContact O-N 3.04Å; T497-Q546 HydrophobicContact CG2-CB 3.76Å; Q546-T548 PolarHBondContact O-N 3.46Å; Q546-D551 PolarHBondContact NE2-OD1 3.38Å; Q546-T552 CarbonylContact C-O 3.52Å; Q546-T552 WeakPolarHBondContact CA-O 3.29Å
547N96.6Very high94.4Very high0 Ų034.5 Ų34.50%021%0.205CC..EExtended strand (participates in β ladder)trans-69.1125.4171.7-172.5-76.3000109.5E462 L493 F549 L550 D551 T552E462-N547 PolarHBondContact OE2-ND2 2.79Å; L493-N547 CarbonylContact O-C 3.53Å; L493-N547 WeakPolarHBondContact O-CA 3.47Å; N547-F549 PolarHBondContact O-N 3.37Å; N547-F549 WeakPolarHBondContact OD1-CA 3.36Å; N547-F549 PolarHBondContact OD1-N 2.64Å; N547-L550 PolarHBondContact OD1-N 3.45Å; N547-D551 WeakPolarHBondContact O-CA 3.42Å; N547-D551 PolarHBondContact O-N 3.41Å; N547-D551 VanDerWaalsContact O-N 3.09Å; N547-T552 VanDerWaalsContact CB-OG1 3.22Å; N547-T552 WeakPolarHBondContact CB-OG1 3.48Å; N547-T552 PolarHBondContact N-O 3.4Å
548T93.9Very high95.1Very high12 Ų1229.8 Ų29.87%0.07417%0.166CC..THydrogen-bonded Turntrans-73.6-14.8-175.262.60000113.6L387 K389 L493 Q495 Q546L387-T548 HydrophobicContact CD2-CG2 3.72Å; L387-T548 HydrophobicContact CG-CG2 4.36Å; K389-T548 HydrophobicContact CB-CG2 4.42Å; K389-T548 HydrophobicContact CG-CG2 4.2Å; L493-T548 PolarHBondContact O-N 3.42Å; L493-T548 PolarHBondContact O-OG1 3.13Å; Q495-T548 HydrophobicContact CB-CG2 3.93Å; Q495-T548 HydrophobicContact CG-CG2 4.3Å; Q546-T548 PolarHBondContact O-N 3.46Å
549F92.8Very high95.7Very high21 Ų2133 Ų339%0.09216%0.161CC..THydrogen-bonded Turntrans-101.4-44.5-177.5-170.4-104000112.8A392 N547 K612 R669 L670 M673A392-F549 HydrophobicContact CB-CB 3.81Å; A392-F549 HydrophobicContact CB-CD2 3.77Å; A392-F549 HydrophobicContact CB-CG 4.25Å; N547-F549 PolarHBondContact O-N 3.37Å; N547-F549 WeakPolarHBondContact OD1-CA 3.36Å; N547-F549 PolarHBondContact OD1-N 2.64Å; F549-K612 WeakPolarHBondContact O-CE 3.19Å; F549-K612 PolarHBondContact O-NZ 2.86Å; F549-R669 HydrophobicContact CE1-CG 4.23Å; F549-R669 HydrophobicContact CZ-CG 4.09Å; F549-L670 HydrophobicContact CE1-CD2 3.6Å; F549-L670 HydrophobicContact CE1-CG 4.24Å; F549-L670 HydrophobicContact CZ-CD2 3.84Å; F549-L670 HydrophobicContact CZ-CG 4.1Å; F549-M673 HydrophobicContact CB-CE 4.48Å; F549-M673 HydrophobicContact CD1-CE 3.41Å; F549-M673 VanDerWaalsContact CD1-CE 3.41Å; F549-M673 HydrophobicContact CD1-SD 3.26Å; F549-M673 WeakPolarHBondContact CD1-SD 3.46Å; F549-M673 HydrophobicContact CE1-CE 3.79Å; F549-M673 HydrophobicContact CE1-SD 3.37Å; F549-M673 WeakPolarHBondContact CE1-SD 3.28Å; F549-M673 HydrophobicContact CG-CE 4.09Å; F549-M673 HydrophobicContact CG-SD 4.42Å
550L91.4Very high96.2Very high6 Ų632.8 Ų32.83%0.03116%0.158CC..THydrogen-bonded Turntrans-101.4-9.5-175.4-61.3-177.2000114.3N547 T552 I609 M673N547-L550 PolarHBondContact OD1-N 3.45Å; L550-T552 HydrophobicContact CB-CG2 3.93Å; L550-T552 PolarHBondContact O-N 2.83Å; L550-I609 HydrophobicContact CD2-CD1 4.29Å; L550-I609 HydrophobicContact CD2-CG1 3.72Å; L550-M673 HydrophobicContact CD1-SD 4.02Å; L550-M673 HydrophobicContact CD2-SD 3.88Å; L550-M673 HydrophobicContact CG-SD 4.01Å
551D93.3Very high96.3Very high55 Ų5530.9 Ų30.929%0.29415%0.148SC..  trans6316.6-177.2-56.8-65000114.7R504 Q546 N547 K612R504-D551 PolarHBondContact NH1-O 3.22Å; Q546-D551 PolarHBondContact NE2-OD1 3.38Å; N547-D551 WeakPolarHBondContact O-CA 3.42Å; N547-D551 PolarHBondContact O-N 3.41Å; N547-D551 VanDerWaalsContact O-N 3.09Å; D551-K612 IonicContact OD2-NZ 3.85Å; D551-K612 PolarHBondContact OD2-NZ 3.4Å; D551-K612 VanDerWaalsContact OD2-NZ 3.12Å
552T96.7Very high96.4Very high0 Ų032.9 Ų32.90%016%0.156CC..  trans-74.4153.517256.30000110.7Q546 N547 L550 D568 N569 T605 L608Q546-T552 CarbonylContact C-O 3.52Å; Q546-T552 WeakPolarHBondContact CA-O 3.29Å; N547-T552 VanDerWaalsContact CB-OG1 3.22Å; N547-T552 WeakPolarHBondContact CB-OG1 3.48Å; N547-T552 PolarHBondContact N-O 3.4Å; L550-T552 HydrophobicContact CB-CG2 3.93Å; L550-T552 PolarHBondContact O-N 2.83Å; T552-D568 VanDerWaalsContact CA-OD1 3.27Å; T552-D568 WeakPolarHBondContact CA-OD1 3.21Å; T552-D568 WeakPolarHBondContact CB-OD1 3.4Å; T552-N569 HydrophobicContact CG2-CB 3.94Å; T552-T605 HydrophobicContact CG2-CG2 4.45Å; T552-L608 HydrophobicContact CG2-CD1 3.93Å
553Q97.9Very high96.5Very high18 Ų1830.1 Ų30.18%0.08414%0.139CC..EExtended strand (participates in β ladder)trans-114.8151.3-172.9-66.2173.5-14.400111.9I500 D501 F545 S567 D568I500-Q553 HydrophobicContact CB-CB 4.42Å; I500-Q553 HydrophobicContact CG2-CB 4.07Å; I500-Q553 HydrophobicContact CG2-CG 4.29Å; D501-Q553 PolarHBondContact O-OE1 3.31Å; F545-Q553 WeakPolarHBondContact O-CA 3.31Å; Q553-S567 WeakPolarHBondContact O-CA 3.39Å; Q553-S567 VanDerWaalsContact O-CB 3.29Å; Q553-S567 WeakPolarHBondContact O-CB 3.45Å; Q553-S567 PolarHBondContact O-OG 3.42Å; Q553-D568 PolarHBondContact N-OD1 2.94Å; Q553-D568 PolarHBondContact N-OD2 3.19Å; Q553-D568 PolarHBondContact O-N 3.23Å
554L98.4Very high96.5Very high0 Ų030.8 Ų30.80%014%0.144CC..EExtended strand (participates in β ladder)trans-135.7121.4175.2170.969.6000110L491 L528 Y544 F545 F565 K566 T572 L576L491-L554 HydrophobicContact CD1-CD2 3.7Å; L528-L554 HydrophobicContact CD1-CD2 4.15Å; L528-L554 HydrophobicContact CD2-CD2 3.77Å; Y544-L554 CarbonylContact C-O 3.51Å; F545-L554 HydrophobicContact CB-CB 4.24Å; F545-L554 HydrophobicContact CD2-CD2 4.26Å; F545-L554 HydrophobicContact CD2-CG 4.44Å; F545-L554 PolarHBondContact N-O 2.6Å; F545-L554 PolarHBondContact O-N 3.09Å; L554-F565 HydrophobicContact CD1-CB 4.37Å; L554-K566 CarbonylContact C-O 3.54Å; L554-K566 WeakPolarHBondContact CA-O 3.43Å; L554-T572 HydrophobicContact CB-CG2 4.47Å; L554-T572 HydrophobicContact CD1-CG2 4.11Å; L554-T572 HydrophobicContact CD2-CG2 4.07Å; L554-T572 HydrophobicContact CG-CG2 4.46Å; L554-L576 HydrophobicContact CD1-CD1 3.86Å; L554-L576 HydrophobicContact CD2-CD1 4.23Å
555E98.4Very high96.6Very high11 Ų1128.1 Ų28.15%0.05113%0.134CC..EExtended strand (participates in β ladder)trans-96.3127.9166.6-174.6174-133.200109.1I500 H502 T542 Y544 I557 F565 K566I500-E555 HydrophobicContact CD1-CB 3.65Å; I500-E555 HydrophobicContact CD1-CG 4.15Å; H502-E555 IonicContact CE1-OE1 2.73Å; T542-E555 HydrophobicContact CG2-CG 4.49Å; Y544-E555 HydrophobicContact CD1-CB 4.38Å; Y544-E555 HydrophobicContact CD1-CG 4.11Å; Y544-E555 HydrophobicContact CE1-CG 3.81Å; E555-I557 HydrophobicContact CG-CD1 3.94Å; E555-I557 HydrophobicContact CG-CG1 3.92Å; E555-F565 CarbonylContact O-C 3.36Å; E555-F565 VanDerWaalsContact O-CA 3.3Å; E555-F565 WeakPolarHBondContact O-CA 3.36Å; E555-K566 HydrophobicContact CB-CB 4.15Å; E555-K566 PolarHBondContact N-O 3.29Å; E555-K566 PolarHBondContact O-N 3.18Å; E555-K566 WeakPolarHBondContact OE2-CD 3.34Å; E555-K566 WeakPolarHBondContact OE2-CE 3.44Å; E555-K566 IonicContact OE2-NZ 3.24Å; E555-K566 PolarHBondContact OE2-NZ 3.19Å
556S97.9Very high96.6Very high0 Ų030.9 Ų30.90%015%0.146CC..EExtended strand (participates in β ladder)trans-121.4110.9172.7-177.90000109.4T542 F543 F565T542-S556 CarbonylContact C-O 3.59Å; T542-S556 VanDerWaalsContact CA-O 3.29Å; T542-S556 WeakPolarHBondContact CA-O 3.27Å; F543-S556 PolarHBondContact N-O 3.15Å; F543-S556 PolarHBondContact O-N 3.23Å; S556-F565 WeakPolarHBondContact OG-CD1 3.43Å; S556-F565 WeakPolarHBondContact OG-CE1 2.9Å
557I97.9Very high96.7Very high40 Ų4029 Ų2921%0.20514%0.137CC..EExtended strand (participates in β ladder)trans-116124.8176-58.5163.1000107.5V541 T542 E555 V564V541-I557 WeakPolarHBondContact O-CA 3.46Å; T542-I557 HydrophobicContact CG2-CG1 3.7Å; E555-I557 HydrophobicContact CG-CD1 3.94Å; E555-I557 HydrophobicContact CG-CG1 3.92Å; I557-V564 PolarHBondContact N-O 2.81Å; I557-V564 PolarHBondContact O-N 2.89Å; I557-V564 VanDerWaalsContact O-O 3.11Å
558Y97.3Very high96.7Very high2 Ų229 Ų291%0.00814%0.137CC..EExtended strand (participates in β ladder)trans-148.7150.7178.856.9-88.3000112.6F517 V520 H521 V524 C540 V541 F543 E562F517-Y558 HydrophobicContact CD2-CD2 4.23Å; F517-Y558 HydrophobicContact CD2-CE2 4.38Å; F517-Y558 AromaticContact CE2-CD2 3.82Å; F517-Y558 HydrophobicContact CE2-CD2 3.82Å; F517-Y558 AromaticContact CE2-CE2 3.65Å; F517-Y558 HydrophobicContact CE2-CE2 3.65Å; F517-Y558 HydrophobicContact CZ-CE2 4.2Å; V520-Y558 HydrophobicContact CG1-CD2 3.74Å; V520-Y558 HydrophobicContact CG1-CG 4.41Å; V520-Y558 HydrophobicContact CG2-CD2 4.26Å; V520-Y558 HydrophobicContact CG2-CG 4.2Å; H521-Y558 HydrophobicContact CB-CE2 4.02Å; H521-Y558 AromaticContact ND1-CE2 3.97Å; H521-Y558 AromaticContact ND1-CZ 3.84Å; H521-Y558 PolarHBondContact ND1-OH 3.05Å; V524-Y558 HydrophobicContact CB-CE1 4.32Å; V524-Y558 HydrophobicContact CG1-CE1 4.01Å; V524-Y558 HydrophobicContact CG2-CD1 3.98Å; V524-Y558 HydrophobicContact CG2-CE1 3.87Å; V524-Y558 HydrophobicContact CG2-CG 4.5Å; C540-Y558 WeakPolarHBondContact CA-O 3.47Å; V541-Y558 HydrophobicContact CB-CE1 4.46Å; V541-Y558 HydrophobicContact CB-CE2 4.14Å; V541-Y558 HydrophobicContact CG1-CE1 4.34Å; V541-Y558 PolarHBondContact N-O 2.78Å; V541-Y558 PolarHBondContact O-N 3.31Å; F543-Y558 HydrophobicContact CD2-CE1 4.06Å; F543-Y558 HydrophobicContact CE2-CE1 4.4Å; F543-Y558 WeakPolarHBondContact CE2-OH 3.19Å; Y558-E562 WeakPolarHBondContact CA-O 3.23Å
559R97.1Very high96.9Very high121 Ų12128.7 Ų28.746%0.45714%0.135SC..EExtended strand (participates in β ladder)trans-143.9-178.9177.460.3179.2136.1-147.7-6.4109.8E539 C540 G561 E562E539-R559 VanDerWaalsContact O-CA 3.23Å; E539-R559 WeakPolarHBondContact O-CA 3.41Å; E539-R559 WeakPolarHBondContact O-CB 3.48Å; C540-R559 HydrophobicContact CB-CB 4.02Å; R559-G561 PolarHBondContact O-N 3.41Å; R559-G561 VanDerWaalsContact O-N 3.15Å; R559-E562 HydrophobicContact CG-CB 4.03Å; R559-E562 IonicContact CZ-OE2 3.78Å; R559-E562 VanDerWaalsContact CZ-OE2 3.24Å; R559-E562 PolarHBondContact N-O 2.97Å; R559-E562 IonicContact NE-OE2 3.76Å; R559-E562 PolarHBondContact NE-OE2 2.94Å; R559-E562 IonicContact NH2-OE2 2.78Å; R559-E562 PolarHBondContact NH2-OE2 3.49Å; R559-E562 PolarHBondContact O-N 3.45Å
560K96.3Very high97Very high159 Ų15927.7 Ų27.769%0.69113%0.131SC*.THydrogen-bonded Turntrans-56.3121.7173.7-176.3-179.4177.9-177.20110.7E562K560-E562 VanDerWaalsContact C-N 3.27Å; K560-E562 PolarHBondContact O-N 3.49Å
561G95.8Very high97.3Very high19 Ų1928 Ų2820%0.19613%0.133CC..THydrogen-bonded Turntrans75.8-1.5175.400000116.8T512 G513 F515 R559T512-G561 WeakPolarHBondContact CA-O 3.44Å; G513-G561 PolarHBondContact N-O 2.97Å; G513-G561 VanDerWaalsContact N-O 3.11Å; G513-G561 VanDerWaalsContact O-CA 3.23Å; G513-G561 WeakPolarHBondContact O-CA 3.36Å; F515-G561 PolarHBondContact O-N 2.8Å; R559-G561 PolarHBondContact O-N 3.41Å; R559-G561 VanDerWaalsContact O-N 3.15Å
562E97.6Very high97.5Very high60 Ų6025.4 Ų25.428%0.2812%0.119SC..EExtended strand (participates in β ladder)trans-143.4134.2179.7-175.1-174.6-149.900111.5L511 T512 F515 Y558 R559 K560 V564L511-E562 CarbonylContact O-C 3.58Å; L511-E562 WeakPolarHBondContact O-CA 3.29Å; T512-E562 HydrophobicContact CG2-CG 4.45Å; F515-E562 VanDerWaalsContact CZ-N 3.28Å; Y558-E562 WeakPolarHBondContact CA-O 3.23Å; R559-E562 HydrophobicContact CG-CB 4.03Å; R559-E562 IonicContact CZ-OE2 3.78Å; R559-E562 VanDerWaalsContact CZ-OE2 3.24Å; R559-E562 PolarHBondContact N-O 2.97Å; R559-E562 IonicContact NE-OE2 3.76Å; R559-E562 PolarHBondContact NE-OE2 2.94Å; R559-E562 IonicContact NH2-OE2 2.78Å; R559-E562 PolarHBondContact NH2-OE2 3.49Å; R559-E562 PolarHBondContact O-N 3.45Å; K560-E562 VanDerWaalsContact C-N 3.27Å; K560-E562 PolarHBondContact O-N 3.49Å; E562-V564 HydrophobicContact CG-CG2 4.37Å
563G97.8Very high97.5Very high0 Ų025.4 Ų25.40%012%0.119CC..EExtended strand (participates in β ladder)trans-136.9129.6170.200000111.1T510 L511T510-G563 CarbonylContact C-O 3.49Å; T510-G563 WeakPolarHBondContact CA-O 3.41Å; L511-G563 PolarHBondContact N-O 3.38Å; L511-G563 PolarHBondContact O-N 2.85Å
564V98.4Very high97.5Very high25 Ų2524.7 Ų24.715%0.15212%0.116CC..EExtended strand (participates in β ladder)trans-119.6120.2-180-177.80000108.5T508 L509 T510 I557 E562 K566T508-V564 HydrophobicContact CG2-CG1 3.87Å; L509-V564 WeakPolarHBondContact O-CA 3.29Å; T510-V564 HydrophobicContact CG2-CG2 4.24Å; I557-V564 PolarHBondContact N-O 2.81Å; I557-V564 PolarHBondContact O-N 2.89Å; I557-V564 VanDerWaalsContact O-O 3.11Å; E562-V564 HydrophobicContact CG-CG2 4.37Å; V564-K566 HydrophobicContact CG1-CG 4.14Å
565F98.4Very high97.4Very high1 Ų125.8 Ų25.80%0.00412%0.122CC..EExtended strand (participates in β ladder)trans-118.5120.7178.8-55.5-94.3000108.6T508 L509 L511 V524 L554 E555 S556 I573 L576 L580T508-F565 CarbonylContact C-O 3.58Å; T508-F565 WeakPolarHBondContact CA-O 3.2Å; L509-F565 HydrophobicContact CB-CB 4.32Å; L509-F565 HydrophobicContact CD2-CD2 4.4Å; L509-F565 PolarHBondContact N-O 3.46Å; L509-F565 PolarHBondContact O-N 2.92Å; L511-F565 HydrophobicContact CD1-CE2 3.82Å; L511-F565 HydrophobicContact CG-CE2 4.34Å; V524-F565 HydrophobicContact CG2-CE1 4.05Å; V524-F565 HydrophobicContact CG2-CZ 4.12Å; L554-F565 HydrophobicContact CD1-CB 4.37Å; E555-F565 CarbonylContact O-C 3.36Å; E555-F565 VanDerWaalsContact O-CA 3.3Å; E555-F565 WeakPolarHBondContact O-CA 3.36Å; S556-F565 WeakPolarHBondContact OG-CD1 3.43Å; S556-F565 WeakPolarHBondContact OG-CE1 2.9Å; F565-I573 HydrophobicContact CB-CD1 4.45Å; F565-L576 HydrophobicContact CB-CD1 3.95Å; F565-L576 HydrophobicContact CD1-CD1 3.96Å; F565-L576 HydrophobicContact CG-CD1 4.1Å; F565-L580 HydrophobicContact CD2-CD1 4.31Å; F565-L580 HydrophobicContact CE1-CD1 4.39Å; F565-L580 HydrophobicContact CE2-CD1 3.75Å; F565-L580 HydrophobicContact CZ-CD1 3.79Å
566K98.3Very high97.4Very high59 Ų5925.3 Ų25.326%0.25712%0.12SC..EExtended strand (participates in β ladder)trans-117.1132.2178.9-49.8-168.6-160128.80110.9M506 N507 T508 L554 E555 V564M506-K566 HydrophobicContact CB-CB 4.28Å; N507-K566 CarbonylContact O-C 3.59Å; N507-K566 WeakPolarHBondContact O-CA 3.28Å; T508-K566 HydrophobicContact CG2-CG 4.17Å; L554-K566 CarbonylContact C-O 3.54Å; L554-K566 WeakPolarHBondContact CA-O 3.43Å; E555-K566 HydrophobicContact CB-CB 4.15Å; E555-K566 PolarHBondContact N-O 3.29Å; E555-K566 PolarHBondContact O-N 3.18Å; E555-K566 WeakPolarHBondContact OE2-CD 3.34Å; E555-K566 WeakPolarHBondContact OE2-CE 3.44Å; E555-K566 IonicContact OE2-NZ 3.24Å; E555-K566 PolarHBondContact OE2-NZ 3.19Å; V564-K566 HydrophobicContact CG1-CG 4.14Å
567S98.2Very high97.4Very high0 Ų027.5 Ų27.50%013%0.129CC..EExtended strand (participates in β ladder)trans-147.4142177.4-174.50000111.9N507 Q553 N569N507-S567 WeakPolarHBondContact CB-O 3.45Å; N507-S567 PolarHBondContact N-O 2.96Å; N507-S567 PolarHBondContact ND2-O 3.02Å; N507-S567 VanDerWaalsContact ND2-O 3.08Å; N507-S567 PolarHBondContact O-N 2.93Å; Q553-S567 WeakPolarHBondContact O-CA 3.39Å; Q553-S567 VanDerWaalsContact O-CB 3.29Å; Q553-S567 WeakPolarHBondContact O-CB 3.45Å; Q553-S567 PolarHBondContact O-OG 3.42Å; S567-N569 PolarHBondContact O-N 3.4Å; S567-N569 PolarHBondContact OG-N 2.87Å; S567-N569 VanDerWaalsContact OG-N 3.16Å; S567-N569 PolarHBondContact OG-O 2.82Å
568D97.3Very high97.3Very high0 Ų028.4 Ų28.40%013%0.134CC..SBendtrans-70.8-8.2169.859.5-3.3000112.4R504 M506 T552 Q553 H604 T605R504-D568 HydrophobicContact CB-CB 4.21Å; R504-D568 WeakPolarHBondContact CD-OD2 3.45Å; R504-D568 IonicContact CZ-OD2 2.96Å; R504-D568 IonicContact NE-OD2 2.99Å; R504-D568 IonicContact NH1-OD2 2.67Å; R504-D568 PolarHBondContact NH1-OD2 2.99Å; M506-D568 HydrophobicContact SD-CB 4.23Å; M506-D568 PolarHBondContact SD-N 3.29Å; M506-D568 VanDerWaalsContact SD-N 3.44Å; T552-D568 VanDerWaalsContact CA-OD1 3.27Å; T552-D568 WeakPolarHBondContact CA-OD1 3.21Å; T552-D568 WeakPolarHBondContact CB-OD1 3.4Å; Q553-D568 PolarHBondContact N-OD1 2.94Å; Q553-D568 PolarHBondContact N-OD2 3.19Å; Q553-D568 PolarHBondContact O-N 3.23Å; D568-H604 IonicContact OD2-NE2 3.52Å; D568-T605 PolarHBondContact O-OG1 2.79Å
569N97.1Very high97.2Very high6 Ų628.5 Ų28.53%0.03214%0.135CC..  trans-108.9122.9173.6-168.84.7000112.5T552 S567 S571 T572 L677T552-N569 HydrophobicContact CG2-CB 3.94Å; S567-N569 PolarHBondContact O-N 3.4Å; S567-N569 PolarHBondContact OG-N 2.87Å; S567-N569 VanDerWaalsContact OG-N 3.16Å; S567-N569 PolarHBondContact OG-O 2.82Å; N569-S571 PolarHBondContact O-N 2.84Å; N569-S571 PolarHBondContact OD1-N 2.89Å; N569-T572 PolarHBondContact O-N 2.96Å; N569-L677 WeakPolarHBondContact OD1-CD1 3.43Å
570I96.2Very high97.2Very high0 Ų022.8 Ų22.80%011%0.114CC..Hα-helixtrans-69.8-30.9179.5-167.9163.1000112.8I573 S574 I597 V602 L677 F684I570-I573 PolarHBondContact O-N 2.88Å; I570-S574 PolarHBondContact O-N 3.14Å; I570-I597 HydrophobicContact CD1-CD1 3.94Å; I570-I597 HydrophobicContact CD1-CG1 4.26Å; I570-I597 HydrophobicContact CD1-CG2 3.65Å; I570-I597 HydrophobicContact CG1-CD1 4.1Å; I570-V602 HydrophobicContact CG2-CG2 4.38Å; I570-L677 HydrophobicContact CG2-CD1 3.39Å; I570-L677 HydrophobicContact CG2-CG 4.41Å; I570-F684 HydrophobicContact CD1-CD2 3.73Å; I570-F684 HydrophobicContact CD1-CE2 4.39Å; I570-F684 HydrophobicContact CD1-CG 4.47Å; I570-F684 HydrophobicContact CG1-CD2 3.57Å; I570-F684 HydrophobicContact CG1-CE2 3.72Å
571S96.6Very high97.2Very high12 Ų1216.9 Ų16.98%0.0849%0.093CC..Hα-helixtrans-66.9-38.2177.9-70.30000111.8N569 I573 S574 I575 L677 D680N569-S571 PolarHBondContact O-N 2.84Å; N569-S571 PolarHBondContact OD1-N 2.89Å; S571-I573 VanDerWaalsContact C-N 3.27Å; S571-I573 PolarHBondContact O-N 3.28Å; S571-S574 WeakPolarHBondContact O-CB 3.4Å; S571-S574 PolarHBondContact O-N 3.45Å; S571-S574 VanDerWaalsContact O-N 3.13Å; S571-I575 VanDerWaalsContact O-CG1 3.27Å; S571-I575 WeakPolarHBondContact O-CG1 3.3Å; S571-I575 PolarHBondContact O-N 2.98Å; S571-L677 WeakPolarHBondContact OG-CA 3.3Å; S571-L677 PolarHBondContact OG-N 2.8Å; S571-D680 VanDerWaalsContact CA-OD2 3.29Å; S571-D680 WeakPolarHBondContact CA-OD2 3.48Å; S571-D680 VanDerWaalsContact CB-OD2 3.26Å; S571-D680 WeakPolarHBondContact CB-OD2 3.42Å; S571-D680 PolarHBondContact OG-OD2 2.93Å
572T97.4Very high97.2Very high1 Ų121 Ų211%0.00611%0.105CC..Hα-helixtrans-55.5-44.8172-56.40000111.1L491 L554 N569 I575 L576L491-T572 HydrophobicContact CD1-CG2 3.85Å; L491-T572 HydrophobicContact CD2-CG2 4.03Å; L554-T572 HydrophobicContact CB-CG2 4.47Å; L554-T572 HydrophobicContact CD1-CG2 4.11Å; L554-T572 HydrophobicContact CD2-CG2 4.07Å; L554-T572 HydrophobicContact CG-CG2 4.46Å; N569-T572 PolarHBondContact O-N 2.96Å; T572-I575 PolarHBondContact O-N 3.45Å; T572-L576 HydrophobicContact CG2-CD1 4.29Å; T572-L576 WeakPolarHBondContact O-CG 3.36Å; T572-L576 PolarHBondContact O-N 2.92Å
573I97.9Very high97.1Very high0 Ų019.1 Ų19.10%010%0.096CC..Hα-helixtrans-67.7-39.5177.4-61.2-57.1000112N507 L509 F565 I570 S571 L576 K577 F684N507-I573 HydrophobicContact CB-CG1 3.99Å; L509-I573 HydrophobicContact CB-CD1 4.21Å; L509-I573 HydrophobicContact CB-CG2 3.75Å; L509-I573 HydrophobicContact CD1-CG2 4.47Å; L509-I573 HydrophobicContact CD2-CG2 4.4Å; L509-I573 HydrophobicContact CG-CG2 4.43Å; F565-I573 HydrophobicContact CB-CD1 4.45Å; I570-I573 PolarHBondContact O-N 2.88Å; S571-I573 VanDerWaalsContact C-N 3.27Å; S571-I573 PolarHBondContact O-N 3.28Å; I573-L576 PolarHBondContact O-N 3.47Å; I573-K577 VanDerWaalsContact O-CB 3.3Å; I573-K577 WeakPolarHBondContact O-CB 3.39Å; I573-K577 PolarHBondContact O-N 3.4Å; I573-F684 HydrophobicContact CB-CZ 4.49Å; I573-F684 HydrophobicContact CG2-CE1 4.49Å; I573-F684 HydrophobicContact CG2-CE2 4.49Å; I573-F684 HydrophobicContact CG2-CZ 3.84Å
574S97.1Very high96.9Very high2 Ų219.2 Ų19.21%0.01410%0.097CC..Hα-helixtrans-59.6-47.6174.8-167.20000111.6I570 S571 K577 D578 D680 K683I570-S574 PolarHBondContact O-N 3.14Å; S571-S574 WeakPolarHBondContact O-CB 3.4Å; S571-S574 PolarHBondContact O-N 3.45Å; S571-S574 VanDerWaalsContact O-N 3.13Å; S574-K577 PolarHBondContact O-N 2.89Å; S574-D578 PolarHBondContact O-N 2.78Å; S574-D680 WeakPolarHBondContact CB-OD1 3.2Å; S574-D680 VanDerWaalsContact OG-CG 3.28Å; S574-D680 PolarHBondContact OG-OD1 3.19Å; S574-K683 PolarHBondContact OG-NZ 3.31Å
575I97.6Very high96.7Very high24 Ų2423 Ų2312%0.12312%0.121CC..Hα-helixtrans-62.3-49.1179-66.4163.7000110.4E462 P490 L491 S571 T572 K577 D578 V579E462-I575 HydrophobicContact CB-CD1 4.5Å; E462-I575 HydrophobicContact CG-CD1 3.91Å; P490-I575 HydrophobicContact CB-CG2 4.04Å; L491-I575 HydrophobicContact CD2-CB 4.08Å; L491-I575 HydrophobicContact CD2-CD1 4.13Å; L491-I575 HydrophobicContact CD2-CG2 3.78Å; L491-I575 HydrophobicContact CG-CG2 4.4Å; S571-I575 VanDerWaalsContact O-CG1 3.27Å; S571-I575 WeakPolarHBondContact O-CG1 3.3Å; S571-I575 PolarHBondContact O-N 2.98Å; T572-I575 PolarHBondContact O-N 3.45Å; I575-K577 PolarHBondContact O-N 2.88Å; I575-D578 PolarHBondContact O-N 3.16Å; I575-V579 HydrophobicContact CG2-CG2 4.3Å; I575-V579 WeakPolarHBondContact O-CB 3.31Å; I575-V579 VanDerWaalsContact O-CG2 3.31Å; I575-V579 WeakPolarHBondContact O-CG2 3.44Å; I575-V579 PolarHBondContact O-N 2.98Å
576L97.9Very high96.5Very high1 Ų129.4 Ų29.41%0.00515%0.148CC..Hα-helixtrans-59.2-46.3177.8-75.7171.9000111.6L491 L509 C527 L554 F565 T572 I573 D578 V579 L580L491-L576 HydrophobicContact CD1-CD1 4.07Å; L491-L576 HydrophobicContact CD1-CD2 3.65Å; L491-L576 HydrophobicContact CD1-CG 3.76Å; L491-L576 HydrophobicContact CG-CD2 4.44Å; L509-L576 HydrophobicContact CD2-CB 3.92Å; C527-L576 HydrophobicContact CB-CD2 4.09Å; L554-L576 HydrophobicContact CD1-CD1 3.86Å; L554-L576 HydrophobicContact CD2-CD1 4.23Å; F565-L576 HydrophobicContact CB-CD1 3.95Å; F565-L576 HydrophobicContact CD1-CD1 3.96Å; F565-L576 HydrophobicContact CG-CD1 4.1Å; T572-L576 HydrophobicContact CG2-CD1 4.29Å; T572-L576 WeakPolarHBondContact O-CG 3.36Å; T572-L576 PolarHBondContact O-N 2.92Å; I573-L576 PolarHBondContact O-N 3.47Å; L576-D578 VanDerWaalsContact C-N 3.34Å; L576-D578 PolarHBondContact O-N 3.21Å; L576-V579 PolarHBondContact O-N 3.16Å; L576-L580 HydrophobicContact CB-CD1 4.16Å; L576-L580 HydrophobicContact CD2-CD1 4.26Å; L576-L580 WeakPolarHBondContact O-CB 3.39Å; L576-L580 WeakPolarHBondContact O-CD1 3.36Å; L576-L580 WeakPolarHBondContact O-CG 3.41Å; L576-L580 PolarHBondContact O-N 3.46Å
577K96.9Very high96.3Very high45 Ų4532.5 Ų32.520%0.19616%0.159CC..Hα-helixtrans-55.8-50.2177.5177.5-173.4170.1-160.60111.1L509 I573 S574 I575 S581 I593 F684L509-K577 HydrophobicContact CD1-CB 4.16Å; L509-K577 HydrophobicContact CD1-CG 4.42Å; L509-K577 HydrophobicContact CD2-CB 4.12Å; I573-K577 VanDerWaalsContact O-CB 3.3Å; I573-K577 WeakPolarHBondContact O-CB 3.39Å; I573-K577 PolarHBondContact O-N 3.4Å; S574-K577 PolarHBondContact O-N 2.89Å; I575-K577 PolarHBondContact O-N 2.88Å; K577-S581 VanDerWaalsContact O-CB 3.24Å; K577-S581 WeakPolarHBondContact O-CB 3.3Å; K577-S581 PolarHBondContact O-N 3.12Å; K577-S581 VanDerWaalsContact O-N 3.08Å; K577-S581 PolarHBondContact O-OG 3.23Å; K577-I593 HydrophobicContact CG-CG2 4.27Å; K577-F684 HydrophobicContact CD-CE1 3.87Å; K577-F684 HydrophobicContact CD-CZ 4.26Å
578D95.9Very high96.1Very high59 Ų5941.6 Ų41.632%0.31620%0.198SC..Hα-helixtrans-65.9-45.4-176.7-74.90.3000111.6S574 I575 L576 K582 K683S574-D578 PolarHBondContact O-N 2.78Å; I575-D578 PolarHBondContact O-N 3.16Å; L576-D578 VanDerWaalsContact C-N 3.34Å; L576-D578 PolarHBondContact O-N 3.21Å; D578-K582 VanDerWaalsContact O-CG 3.31Å; D578-K582 WeakPolarHBondContact O-CG 2.99Å; D578-K582 PolarHBondContact O-N 3.31Å; D578-K582 VanDerWaalsContact O-N 3.11Å; D578-K683 IonicContact OD1-NZ 2.77Å; D578-K683 PolarHBondContact OD1-NZ 2.78Å; D578-K683 IonicContact OD2-NZ 3.29Å; D578-K683 PolarHBondContact OD2-NZ 2.86Å
579V96.8Very high96Very high4 Ų442.6 Ų42.62%0.02420%0.203CC..Hα-helixtrans-71-45.7-177.2177.70000111.8Y465 P490 F526 C527 I575 L576 S581 K582 E583Y465-V579 HydrophobicContact CD1-CG2 4.24Å; Y465-V579 HydrophobicContact CE1-CG2 3.66Å; P490-V579 HydrophobicContact CB-CG2 3.94Å; P490-V579 HydrophobicContact CG-CG1 3.97Å; P490-V579 HydrophobicContact CG-CG2 4.09Å; F526-V579 HydrophobicContact CD1-CG1 3.97Å; F526-V579 HydrophobicContact CE1-CG1 3.87Å; C527-V579 VanDerWaalsContact SG-CG1 3.53Å; I575-V579 HydrophobicContact CG2-CG2 4.3Å; I575-V579 WeakPolarHBondContact O-CB 3.31Å; I575-V579 VanDerWaalsContact O-CG2 3.31Å; I575-V579 WeakPolarHBondContact O-CG2 3.44Å; I575-V579 PolarHBondContact O-N 2.98Å; L576-V579 PolarHBondContact O-N 3.16Å; V579-S581 VanDerWaalsContact C-N 3.29Å; V579-S581 PolarHBondContact O-N 2.92Å; V579-K582 WeakPolarHBondContact O-CB 2.92Å; V579-K582 PolarHBondContact O-N 2.76Å; V579-K582 VanDerWaalsContact O-N 3.1Å; V579-E583 HydrophobicContact CG1-CG 4.43Å; V579-E583 PolarHBondContact O-N 3.31Å
580L96.6Very high95.7Very high1 Ų149.4 Ų49.41%0.00524%0.239CC..Hα-helixtrans-65.5-35.3179.7-63.3171.7000111L511 W523 F565 L576 E583 A584L511-L580 HydrophobicContact CD1-CB 3.89Å; L511-L580 HydrophobicContact CD1-CD1 3.49Å; L511-L580 VanDerWaalsContact CD1-CD1 3.49Å; L511-L580 HydrophobicContact CD1-CG 4.23Å; W523-L580 HydrophobicContact CB-CD2 3.61Å; W523-L580 HydrophobicContact CG-CD2 4.46Å; F565-L580 HydrophobicContact CD2-CD1 4.31Å; F565-L580 HydrophobicContact CE1-CD1 4.39Å; F565-L580 HydrophobicContact CE2-CD1 3.75Å; F565-L580 HydrophobicContact CZ-CD1 3.79Å; L576-L580 HydrophobicContact CB-CD1 4.16Å; L576-L580 HydrophobicContact CD2-CD1 4.26Å; L576-L580 WeakPolarHBondContact O-CB 3.39Å; L576-L580 WeakPolarHBondContact O-CD1 3.36Å; L576-L580 WeakPolarHBondContact O-CG 3.41Å; L576-L580 PolarHBondContact O-N 3.46Å; L580-E583 PolarHBondContact O-N 3.41Å; L580-A584 WeakPolarHBondContact O-CB 3.3Å; L580-A584 PolarHBondContact O-N 2.89Å
581S95.7Very high95.6Very high36 Ų3651.1 Ų51.125%0.25225%0.249SC..Hα-helixtrans-61.7-43.1171.3-59.70000112K577 V579 T585 I593K577-S581 VanDerWaalsContact O-CB 3.24Å; K577-S581 WeakPolarHBondContact O-CB 3.3Å; K577-S581 PolarHBondContact O-N 3.12Å; K577-S581 VanDerWaalsContact O-N 3.08Å; K577-S581 PolarHBondContact O-OG 3.23Å; V579-S581 VanDerWaalsContact C-N 3.29Å; V579-S581 PolarHBondContact O-N 2.92Å; S581-T585 WeakPolarHBondContact O-CB 3.46Å; S581-T585 PolarHBondContact O-N 2.8Å; S581-T585 PolarHBondContact O-OG1 2.98Å; S581-I593 WeakPolarHBondContact OG-CD1 3.45Å
582K95.7Very high95.6Very high105 Ų10555.7 Ų55.746%0.45727%0.272SS..Hα-helixtrans-63.8-46.1176.4-73.2172.2-175.1177.70111.5D578 V579 T585 K586D578-K582 VanDerWaalsContact O-CG 3.31Å; D578-K582 WeakPolarHBondContact O-CG 2.99Å; D578-K582 PolarHBondContact O-N 3.31Å; D578-K582 VanDerWaalsContact O-N 3.11Å; V579-K582 WeakPolarHBondContact O-CB 2.92Å; V579-K582 PolarHBondContact O-N 2.76Å; V579-K582 VanDerWaalsContact O-N 3.1Å; K582-T585 PolarHBondContact O-N 2.98Å; K582-K586 WeakPolarHBondContact O-CG 3.39Å; K582-K586 PolarHBondContact O-N 3.41Å
583E95.1Very high95.5Very high20 Ų2057.8 Ų57.89%0.09328%0.283CS..Hα-helixtrans-64.7-40.2179.7-73.5-54.3121.400112.6W523 F526 V579 L580 K586 R587W523-E583 HydrophobicContact CG-CB 4.13Å; F526-E583 HydrophobicContact CD1-CG 4.2Å; V579-E583 HydrophobicContact CG1-CG 4.43Å; V579-E583 PolarHBondContact O-N 3.31Å; L580-E583 PolarHBondContact O-N 3.41Å; E583-K586 PolarHBondContact O-N 3.41Å; E583-K586 WeakPolarHBondContact OE1-CD 3.26Å; E583-K586 WeakPolarHBondContact OE1-CE 3.5Å; E583-K586 IonicContact OE1-NZ 2.82Å; E583-K586 PolarHBondContact OE1-NZ 3.12Å; E583-R587 PolarHBondContact O-N 3.05Å
584A94.1Very high95.5Very high2 Ų260.4 Ų60.42%0.01730%0.301CS..Hα-helixtrans-65-41.9173.300000112.1W523 L580 K586 R587 K588 I589 L591W523-A584 HydrophobicContact CH2-CB 4.05Å; W523-A584 HydrophobicContact CZ2-CB 4.17Å; L580-A584 WeakPolarHBondContact O-CB 3.3Å; L580-A584 PolarHBondContact O-N 2.89Å; A584-K586 PolarHBondContact O-N 3.44Å; A584-R587 CarbonylContact O-C 3.56Å; A584-R587 PolarHBondContact O-N 2.95Å; A584-R587 VanDerWaalsContact O-N 3.12Å; A584-K588 PolarHBondContact O-N 2.92Å; A584-I589 HydrophobicContact CB-CB 4.3Å; A584-I589 PolarHBondContact O-N 3Å; A584-L591 HydrophobicContact CB-CD1 3.29Å; A584-L591 HydrophobicContact CB-CD2 4.47Å; A584-L591 HydrophobicContact CB-CG 3.55Å
585T94.7Very high95.4Very high106 Ų10665.2 Ų65.265%0.6532%0.32SS*.Hα-helixtrans-62.3-42.3176.9-56.40000111.6S581 K582 R587 K588S581-T585 WeakPolarHBondContact O-CB 3.46Å; S581-T585 PolarHBondContact O-N 2.8Å; S581-T585 PolarHBondContact O-OG1 2.98Å; K582-T585 PolarHBondContact O-N 2.98Å; T585-R587 PolarHBondContact O-N 2.89Å; T585-K588 PolarHBondContact O-N 3.37Å
586K94.6Very high95.4Very high135 Ų13570.9 Ų70.959%0.58735%0.346SS*.Hα-helixtrans-56.3-36.6174.3-75.2175.8-176.1173.80112.2K582 E583 A584K582-K586 WeakPolarHBondContact O-CG 3.39Å; K582-K586 PolarHBondContact O-N 3.41Å; E583-K586 PolarHBondContact O-N 3.41Å; E583-K586 WeakPolarHBondContact OE1-CD 3.26Å; E583-K586 WeakPolarHBondContact OE1-CE 3.5Å; E583-K586 IonicContact OE1-NZ 2.82Å; E583-K586 PolarHBondContact OE1-NZ 3.12Å; A584-K586 PolarHBondContact O-N 3.44Å
587R93Very high95.2Very high124 Ų12472.9 Ų72.947%0.46836%0.356SS..THydrogen-bonded Turntrans-91.93.7177.7-64.5-168.7-178.8-137.53.6114.3S522 E583 A584 T585 I589S522-R587 PolarHBondContact OG-NH2 2.86Å; E583-R587 PolarHBondContact O-N 3.05Å; A584-R587 CarbonylContact O-C 3.56Å; A584-R587 PolarHBondContact O-N 2.95Å; A584-R587 VanDerWaalsContact O-N 3.12Å; T585-R587 PolarHBondContact O-N 2.89Å; R587-I589 HydrophobicContact CB-CD1 3.88Å; R587-I589 HydrophobicContact CB-CG1 4.22Å; R587-I589 PolarHBondContact O-N 3.47Å
588K94.4Very high95.1Very high191 Ų19173.6 Ų73.683%0.8336%0.362SS*.THydrogen-bonded Turntrans56.834.6-176.5-54.2178.4179.6178.30113.3A584 T585A584-K588 PolarHBondContact O-N 2.92Å; T585-K588 PolarHBondContact O-N 3.37Å
589I93.9Very high94.7Very high20 Ų2075.4 Ų75.410%0.10337%0.368CS..  trans-94.4124.2175.4-68.1163.4000108.7F515 W523 A584 R587 L591F515-I589 HydrophobicContact CB-CD1 4.26Å; F515-I589 HydrophobicContact CB-CG2 4.37Å; W523-I589 HydrophobicContact CH2-CD1 4.04Å; W523-I589 HydrophobicContact CH2-CG2 4.24Å; W523-I589 HydrophobicContact CZ2-CD1 3.68Å; A584-I589 HydrophobicContact CB-CB 4.3Å; A584-I589 PolarHBondContact O-N 3Å; R587-I589 HydrophobicContact CB-CD1 3.88Å; R587-I589 HydrophobicContact CB-CG1 4.22Å; R587-I589 PolarHBondContact O-N 3.47Å; I589-L591 HydrophobicContact CG2-CD2 4.06Å; I589-L591 HydrophobicContact CG2-CG 4.42Å; I589-L591 PolarHBondContact O-N 3.19Å
590N92.3Very high94.6Very high149 Ų14979.1 Ų79.180%0.79739%0.391SS*.  trans-80.6111.3174.1-65.7-28.7000109.2
591L94Very high94.5Very high37 Ų3779.1 Ų79.119%0.19439%0.391CS..EExtended strand (participates in β ladder)trans-96.8138.5174-67.6-178.6000110.9L511 F515 W523 A584 I589 I593L511-L591 HydrophobicContact CD2-CD1 4.45Å; F515-L591 HydrophobicContact CD1-CD2 3.53Å; F515-L591 HydrophobicContact CE1-CD2 3.56Å; W523-L591 HydrophobicContact CH2-CD2 4.21Å; W523-L591 HydrophobicContact CZ3-CD1 4.3Å; W523-L591 HydrophobicContact CZ3-CD2 4.19Å; A584-L591 HydrophobicContact CB-CD1 3.29Å; A584-L591 HydrophobicContact CB-CD2 4.47Å; A584-L591 HydrophobicContact CB-CG 3.55Å; I589-L591 HydrophobicContact CG2-CD2 4.06Å; I589-L591 HydrophobicContact CG2-CG 4.42Å; I589-L591 PolarHBondContact O-N 3.19Å; L591-I593 HydrophobicContact CB-CD1 4.46Å; L591-I593 HydrophobicContact CB-CG1 4.06Å
592N96.5Very high94.5Very high108 Ų10877.4 Ų77.458%0.57838%0.379SS*.EExtended strand (participates in β ladder)trans-97.5118.4161.1-178.424.6000108.5T512T512-N592 PolarHBondContact N-O 2.8Å; T512-N592 PolarHBondContact O-N 3.24Å; T512-N592 WeakPolarHBondContact OG1-CB 3.36Å; T512-N592 PolarHBondContact OG1-O 3.31Å
593I95.9Very high94.4Very high44 Ų4475.2 Ų75.223%0.22637%0.37CS..EExtended strand (participates in β ladder)trans-112.9121.8-173.3-52.3-170.1000108.4L509 L511 K577 S581 L591L509-I593 HydrophobicContact CD1-CG2 3.59Å; L511-I593 HydrophobicContact CD2-CB 4.06Å; L511-I593 HydrophobicContact CD2-CD1 3.82Å; L511-I593 HydrophobicContact CD2-CG1 3.54Å; L511-I593 HydrophobicContact CD2-CG2 3.79Å; K577-I593 HydrophobicContact CG-CG2 4.27Å; S581-I593 WeakPolarHBondContact OG-CD1 3.45Å; L591-I593 HydrophobicContact CB-CD1 4.46Å; L591-I593 HydrophobicContact CB-CG1 4.06Å
594S96.8Very high94.4Very high56 Ų5676.4 Ų76.439%0.39238%0.376SS..EExtended strand (participates in β ladder)trans-123.2148173.556.50000109.5T510T510-S594 WeakPolarHBondContact CB-OG 3.25Å; T510-S594 PolarHBondContact N-O 3.1Å; T510-S594 PolarHBondContact O-N 2.97Å; T510-S594 PolarHBondContact O-OG 3.49Å
595Y95.4Very high94.5Very high103 Ų10376.4 Ų76.440%0.40438%0.375SS..EExtended strand (participates in β ladder)trans-141.7148.4179.153.8-93.3000110.6T508 I597 F684T508-Y595 CarbonylContact O-C 3.52Å; T508-Y595 WeakPolarHBondContact O-CA 3.27Å; Y595-I597 HydrophobicContact CD2-CD1 4.43Å; Y595-I597 HydrophobicContact CD2-CG1 4.12Å; Y595-F684 HydrophobicContact CD1-CD1 4.19Å; Y595-F684 HydrophobicContact CD1-CE1 4.08Å; Y595-F684 AromaticContact CD2-CD1 3.59Å; Y595-F684 HydrophobicContact CD2-CD1 3.59Å; Y595-F684 HydrophobicContact CD2-CE1 4.05Å; Y595-F684 HydrophobicContact CE1-CD1 4.21Å; Y595-F684 HydrophobicContact CE1-CE1 4.42Å; Y595-F684 HydrophobicContact CE2-CB 4.39Å; Y595-F684 AromaticContact CE2-CD1 3.59Å; Y595-F684 HydrophobicContact CE2-CD1 3.59Å; Y595-F684 HydrophobicContact CE2-CE1 4.38Å; Y595-F684 HydrophobicContact CE2-CG 4.45Å; Y595-F684 AromaticContact CG-CD1 3.9Å; Y595-F684 HydrophobicContact CG-CD1 3.9Å; Y595-F684 AromaticContact CG-CE1 3.89Å; Y595-F684 HydrophobicContact CG-CE1 3.89Å; Y595-F684 AromaticContact CZ-CD1 3.92Å
596E96.4Very high94.5Very high143 Ų14371.7 Ų71.767%0.66835%0.346SS*.EExtended strand (participates in β ladder)trans-128.2118.7175.9-175.5177.1-176.800107.9N507 T508N507-E596 CarbonylContact C-O 3.42Å; N507-E596 WeakPolarHBondContact CA-O 3.24Å; T508-E596 PolarHBondContact N-O 3.26Å; T508-E596 PolarHBondContact O-N 3.42Å
597I95.6Very high94.5Very high42 Ų4271 Ų7122%0.21534%0.343CS..  trans-104.9128.6-176.7-58.2-54000108.9N507 I570 Y595 F684N507-I597 HydrophobicContact CB-CD1 4.13Å; N507-I597 WeakPolarHBondContact OD1-CA 3.2Å; N507-I597 WeakPolarHBondContact OD1-CG2 3.36Å; I570-I597 HydrophobicContact CD1-CD1 3.94Å; I570-I597 HydrophobicContact CD1-CG1 4.26Å; I570-I597 HydrophobicContact CD1-CG2 3.65Å; I570-I597 HydrophobicContact CG1-CD1 4.1Å; Y595-I597 HydrophobicContact CD2-CD1 4.43Å; Y595-I597 HydrophobicContact CD2-CG1 4.12Å; I597-F684 HydrophobicContact CD1-CD1 4.32Å; I597-F684 HydrophobicContact CD1-CD2 4.28Å; I597-F684 HydrophobicContact CD1-CG 4.17Å; I597-F684 HydrophobicContact CG1-CB 4.2Å; I597-F684 HydrophobicContact CG1-CG 4.26Å
598N93.9Very high94.6Very high60 Ų6067.3 Ų67.332%0.32133%0.333SS..  trans-89.2113.2171.8-173-30.4000108.8P505 N507 V600 S601P505-N598 HydrophobicContact CB-CB 4.41Å; P505-N598 WeakPolarHBondContact CB-ND2 3.34Å; N507-N598 PolarHBondContact OD1-N 2.96Å; N598-V600 PolarHBondContact O-N 2.87Å; N598-V600 WeakPolarHBondContact OD1-CB 3.15Å; N598-V600 PolarHBondContact OD1-N 2.64Å; N598-S601 VanDerWaalsContact O-CB 3.31Å; N598-S601 WeakPolarHBondContact O-CB 3.23Å; N598-S601 PolarHBondContact O-N 2.73Å; N598-S601 PolarHBondContact O-OG 3Å
599E88Confident94.6Very high98 Ų9858.4 Ų58.446%0.45829%0.294SS..Hα-helixtrans-58.7-23.6-177.1-65.1-71.6161.500113S601 K685E599-S601 VanDerWaalsContact C-N 3.34Å; E599-K685 WeakPolarHBondContact OE1-CE 3.33Å; E599-K685 IonicContact OE1-NZ 3.79Å; E599-K685 PolarHBondContact OE1-NZ 2.9Å; E599-K685 IonicContact OE2-NZ 2.94Å; E599-K685 PolarHBondContact OE2-NZ 3.27Å
600V94.3Very high94.6Very high82 Ų8259.2 Ų59.250%0.49730%0.297SS..Hα-helixtrans-77.5-20177.3-1720000112.2P505 N598 V602 Q603 H604P505-V600 HydrophobicContact CB-CB 4.42Å; N598-V600 PolarHBondContact O-N 2.87Å; N598-V600 WeakPolarHBondContact OD1-CB 3.15Å; N598-V600 PolarHBondContact OD1-N 2.64Å; V600-V602 VanDerWaalsContact C-N 3.29Å; V600-V602 PolarHBondContact O-N 2.73Å; V600-Q603 PolarHBondContact O-N 2.67Å; V600-H604 PolarHBondContact O-N 2.91Å
601S95.1Very high94.6Very high0 Ų055.5 Ų55.50%028%0.282CS..Hα-helixtrans-62.1-37.9-17685.80000112.1P505 N507 N598 E599 Q603 H604 T605P505-S601 VanDerWaalsContact O-CB 3.26Å; P505-S601 WeakPolarHBondContact O-CB 3.37Å; N507-S601 VanDerWaalsContact ND2-CB 3.32Å; N507-S601 WeakPolarHBondContact ND2-CB 3.46Å; N507-S601 PolarHBondContact ND2-OG 3.37Å; N507-S601 PolarHBondContact OD1-OG 3.36Å; N598-S601 VanDerWaalsContact O-CB 3.31Å; N598-S601 WeakPolarHBondContact O-CB 3.23Å; N598-S601 PolarHBondContact O-N 2.73Å; N598-S601 PolarHBondContact O-OG 3Å; E599-S601 VanDerWaalsContact C-N 3.34Å; S601-Q603 PolarHBondContact O-N 2.96Å; S601-H604 WeakPolarHBondContact O-CB 3.29Å; S601-H604 PolarHBondContact O-N 2.89Å; S601-H604 VanDerWaalsContact O-N 3.17Å; S601-T605 PolarHBondContact O-N 3.04Å; S601-T605 PolarHBondContact O-OG1 3.48Å; S601-T605 VanDerWaalsContact O-OG1 3.07Å
602V94.6Very high94.6Very high1 Ų156.9 Ų56.91%0.00629%0.286CS..Hα-helixtrans-63.5-44.9178.8176.80000110.6I570 V600 H604 T605 L606 L677 K681 F712I570-V602 HydrophobicContact CG2-CG2 4.38Å; V600-V602 VanDerWaalsContact C-N 3.29Å; V600-V602 PolarHBondContact O-N 2.73Å; V602-H604 VanDerWaalsContact C-N 3.27Å; V602-H604 PolarHBondContact O-N 2.91Å; V602-T605 PolarHBondContact O-N 2.84Å; V602-L606 HydrophobicContact CG1-CD1 4.18Å; V602-L606 HydrophobicContact CG1-CG 4.49Å; V602-L606 WeakPolarHBondContact O-CB 3.48Å; V602-L606 WeakPolarHBondContact O-CG 3.41Å; V602-L606 PolarHBondContact O-N 2.91Å; V602-L677 HydrophobicContact CG1-CD2 4.47Å; V602-K681 HydrophobicContact CG1-CD 4.17Å; V602-K681 HydrophobicContact CG2-CB 4.44Å; V602-K681 HydrophobicContact CG2-CD 4.01Å; V602-K681 HydrophobicContact CG2-CG 4.11Å; V602-F712 HydrophobicContact CG1-CD1 3.56Å; V602-F712 HydrophobicContact CG1-CE1 3.99Å; V602-F712 HydrophobicContact CG1-CG 4.45Å
603Q94.1Very high94.3Very high59 Ų5951.8 Ų51.828%0.27626%0.259SS..Hα-helixtrans-64-36176.1-65.4-177.4-4.900111.2V600 S601 K607 I709 D713V600-Q603 PolarHBondContact O-N 2.67Å; S601-Q603 PolarHBondContact O-N 2.96Å; Q603-K607 VanDerWaalsContact O-CG 3.25Å; Q603-K607 WeakPolarHBondContact O-CG 3.28Å; Q603-K607 PolarHBondContact O-N 2.86Å; Q603-I709 HydrophobicContact CG-CG2 4.26Å; Q603-D713 PolarHBondContact NE2-OD2 2.84Å
604H95.3Very high94.2Very high45 Ų4554 Ų5421%0.20827%0.268CS..Hα-helixtrans-62.4-49.6173.2176.975.3000111.9P505 D568 V600 S601 V602 L606 K607 L608P505-H604 HydrophobicContact CG-CB 3.66Å; D568-H604 IonicContact OD2-NE2 3.52Å; V600-H604 PolarHBondContact O-N 2.91Å; S601-H604 WeakPolarHBondContact O-CB 3.29Å; S601-H604 PolarHBondContact O-N 2.89Å; S601-H604 VanDerWaalsContact O-N 3.17Å; V602-H604 VanDerWaalsContact C-N 3.27Å; V602-H604 PolarHBondContact O-N 2.91Å; H604-L606 PolarHBondContact O-N 3.48Å; H604-K607 WeakPolarHBondContact O-CB 3.16Å; H604-K607 PolarHBondContact O-N 2.87Å; H604-K607 VanDerWaalsContact O-N 3.13Å; H604-L608 PolarHBondContact O-N 2.82Å
605T95.2Very high93.9Very high1 Ų156.2 Ų56.21%0.00627%0.269CS..Hα-helixtrans-62.4-41.9177.9-50.90000112.2T552 D568 S601 V602 K607 L608 I609 L677T552-T605 HydrophobicContact CG2-CG2 4.45Å; D568-T605 PolarHBondContact O-OG1 2.79Å; S601-T605 PolarHBondContact O-N 3.04Å; S601-T605 PolarHBondContact O-OG1 3.48Å; S601-T605 VanDerWaalsContact O-OG1 3.07Å; V602-T605 PolarHBondContact O-N 2.84Å; T605-K607 VanDerWaalsContact C-N 3.28Å; T605-K607 PolarHBondContact O-N 3.21Å; T605-L608 WeakPolarHBondContact O-CB 3.24Å; T605-L608 PolarHBondContact O-N 3.31Å; T605-L608 VanDerWaalsContact O-N 3.1Å; T605-I609 HydrophobicContact CG2-CD1 4.01Å; T605-I609 WeakPolarHBondContact O-CG1 3.4Å; T605-I609 PolarHBondContact O-N 2.84Å; T605-L677 HydrophobicContact CG2-CD1 4.25Å; T605-L677 HydrophobicContact CG2-CD2 4Å
606L94.9Very high93.8Very high8 Ų852.5 Ų52.54%0.04226%0.255CS..Hα-helixtrans-61.7-36.2175.1-71.3175.4000112V602 H604 I609 H610 I674 L677 L708 I709 F712V602-L606 HydrophobicContact CG1-CD1 4.18Å; V602-L606 HydrophobicContact CG1-CG 4.49Å; V602-L606 WeakPolarHBondContact O-CB 3.48Å; V602-L606 WeakPolarHBondContact O-CG 3.41Å; V602-L606 PolarHBondContact O-N 2.91Å; H604-L606 PolarHBondContact O-N 3.48Å; L606-I609 PolarHBondContact O-N 3.35Å; L606-H610 WeakPolarHBondContact O-CB 3.26Å; L606-H610 PolarHBondContact O-N 2.77Å; L606-I674 HydrophobicContact CD2-CG2 4.49Å; L606-L677 HydrophobicContact CD2-CD2 4.01Å; L606-L677 HydrophobicContact CG-CD2 4.24Å; L606-L708 HydrophobicContact CD2-CD2 4.15Å; L606-I709 HydrophobicContact CD1-CG1 4.04Å; L606-F712 HydrophobicContact CD1-CB 4.41Å; L606-F712 HydrophobicContact CD1-CD1 4.23Å; L606-F712 HydrophobicContact CD1-CD2 4.06Å; L606-F712 HydrophobicContact CD1-CE1 4.49Å; L606-F712 HydrophobicContact CD1-CE2 4.34Å; L606-F712 HydrophobicContact CD1-CG 3.98Å; L606-F712 HydrophobicContact CD2-CE2 4.18Å; L606-F712 HydrophobicContact CD2-CZ 4.1Å
607K95Very high93.4Very high120 Ų12047.4 Ų47.452%0.52223%0.232SC..Hα-helixtrans-67-34173.3-74.6171.1-177177.60112.7Q603 H604 T605 P611Q603-K607 VanDerWaalsContact O-CG 3.25Å; Q603-K607 WeakPolarHBondContact O-CG 3.28Å; Q603-K607 PolarHBondContact O-N 2.86Å; H604-K607 WeakPolarHBondContact O-CB 3.16Å; H604-K607 PolarHBondContact O-N 2.87Å; H604-K607 VanDerWaalsContact O-N 3.13Å; T605-K607 VanDerWaalsContact C-N 3.28Å; T605-K607 PolarHBondContact O-N 3.21Å; K607-P611 WeakPolarHBondContact O-CD 3.49Å
608L94.6Very high93.2Very high47 Ų4749.2 Ų49.225%0.24624%0.242CC..Hα-helixtrans-70.3-36.4174.1-67.4175.9000112.2T552 H604 T605T552-L608 HydrophobicContact CG2-CD1 3.93Å; H604-L608 PolarHBondContact O-N 2.82Å; T605-L608 WeakPolarHBondContact O-CB 3.24Å; T605-L608 PolarHBondContact O-N 3.31Å; T605-L608 VanDerWaalsContact O-N 3.1Å
609I94.1Very high93.1Very high4 Ų446.6 Ų46.62%0.02123%0.227CC..Hα-helixtrans-72.9-34178.3-68.8167.1000111.6L550 T605 L606 K612 L613 L670 I674L550-I609 HydrophobicContact CD2-CD1 4.29Å; L550-I609 HydrophobicContact CD2-CG1 3.72Å; T605-I609 HydrophobicContact CG2-CD1 4.01Å; T605-I609 WeakPolarHBondContact O-CG1 3.4Å; T605-I609 PolarHBondContact O-N 2.84Å; L606-I609 PolarHBondContact O-N 3.35Å; I609-K612 WeakPolarHBondContact O-CB 3.42Å; I609-K612 PolarHBondContact O-N 2.93Å; I609-L613 HydrophobicContact CG2-CD1 3.96Å; I609-L613 HydrophobicContact CG2-CG 4.01Å; I609-L613 PolarHBondContact O-N 3.12Å; I609-L670 HydrophobicContact CG2-CD2 4.11Å; I609-I674 HydrophobicContact CD1-CG1 4.03Å; I609-I674 HydrophobicContact CG2-CD1 3.83Å; I609-I674 HydrophobicContact CG2-CG1 4.09Å
610H93.9Very high93.2Very high36 Ų3642.7 Ų42.717%0.16721%0.212CC..Hα-helixtrans-52.7-50.3-170.2168.980.3000114.9L606 K612 L613 E614 Y703 Q705L606-H610 WeakPolarHBondContact O-CB 3.26Å; L606-H610 PolarHBondContact O-N 2.77Å; H610-K612 VanDerWaalsContact C-N 3.27Å; H610-K612 PolarHBondContact O-N 3.38Å; H610-L613 PolarHBondContact O-N 3.41Å; H610-E614 WeakPolarHBondContact O-CB 3.41Å; H610-E614 PolarHBondContact O-N 2.89Å; H610-Y703 VanDerWaalsContact CA-OH 3.3Å; H610-Y703 WeakPolarHBondContact CA-OH 3.48Å; H610-Y703 AromaticContact ND1-CE1 3.86Å; H610-Y703 AromaticContact ND1-CZ 3.58Å; H610-Y703 PolarHBondContact ND1-OH 3.13Å; H610-Y703 PolarHBondContact O-OH 3.41Å; H610-Q705 PolarHBondContact CE1-OE1 3.11Å
611P94Very high93Very high72 Ų7245 Ų4547%0.46822%0.216SC..Hα-helixtrans-61.7-34.5178.8-23.533.5000113.1K607 Y615K607-P611 WeakPolarHBondContact O-CD 3.49Å; P611-Y615 VanDerWaalsContact O-CB 3.32Å; P611-Y615 WeakPolarHBondContact O-CB 3.49Å; P611-Y615 PolarHBondContact O-N 2.95Å
612K92.2Very high92.9Very high66 Ų6648.4 Ų48.429%0.28723%0.23SC..Hα-helixtrans-69.2-44.6179.6-58.2-177.2-163.6-120.20110.1F549 D551 I609 H610 Q616 L670F549-K612 WeakPolarHBondContact O-CE 3.19Å; F549-K612 PolarHBondContact O-NZ 2.86Å; D551-K612 IonicContact OD2-NZ 3.85Å; D551-K612 PolarHBondContact OD2-NZ 3.4Å; D551-K612 VanDerWaalsContact OD2-NZ 3.12Å; I609-K612 WeakPolarHBondContact O-CB 3.42Å; I609-K612 PolarHBondContact O-N 2.93Å; H610-K612 VanDerWaalsContact C-N 3.27Å; H610-K612 PolarHBondContact O-N 3.38Å; K612-Q616 WeakPolarHBondContact O-CG 3.46Å; K612-Q616 PolarHBondContact O-N 3.41Å; K612-L670 HydrophobicContact CB-CD1 4.27Å; K612-L670 HydrophobicContact CB-CD2 4.27Å
613L91.8Very high92.8Very high1 Ų149 Ų491%0.00523%0.234CC..Hα-helixtrans-64.3-47.2175.1-89.9-176.3000112.8I609 H610 Y615 Q616 L617 L670 Y671 I674 L700 Y703I609-L613 HydrophobicContact CG2-CD1 3.96Å; I609-L613 HydrophobicContact CG2-CG 4.01Å; I609-L613 PolarHBondContact O-N 3.12Å; H610-L613 PolarHBondContact O-N 3.41Å; L613-Y615 VanDerWaalsContact C-N 3.3Å; L613-Y615 PolarHBondContact O-N 2.94Å; L613-Q616 PolarHBondContact O-N 3.01Å; L613-L617 WeakPolarHBondContact O-CG 3.14Å; L613-L617 PolarHBondContact O-N 2.73Å; L613-L670 HydrophobicContact CD2-CB 3.67Å; L613-L670 HydrophobicContact CD2-CD1 3.73Å; L613-L670 HydrophobicContact CD2-CG 4.28Å; L613-L670 HydrophobicContact CG-CB 4.18Å; L613-L670 HydrophobicContact CG-CD1 4.04Å; L613-Y671 HydrophobicContact CD2-CD1 4.08Å; L613-Y671 HydrophobicContact CD2-CE1 3.85Å; L613-I674 HydrophobicContact CD1-CD1 3.35Å; L613-I674 HydrophobicContact CG-CD1 4.35Å; L613-L700 HydrophobicContact CD1-CD2 4.31Å; L613-Y703 HydrophobicContact CB-CE1 4.44Å; L613-Y703 HydrophobicContact CB-CE2 4.16Å; L613-Y703 HydrophobicContact CD1-CD2 4.16Å; L613-Y703 HydrophobicContact CD1-CE2 3.5Å; L613-Y703 VanDerWaalsContact CD1-CE2 3.5Å
614E92.2Very high92.8Very high90 Ų9053 Ų5342%0.42125%0.253SS..Hα-helixtrans-58-44.9179.2-176.9-179.6-139.100111H610 Q616 L617 L618 Y703H610-E614 WeakPolarHBondContact O-CB 3.41Å; H610-E614 PolarHBondContact O-N 2.89Å; E614-Q616 PolarHBondContact O-N 2.65Å; E614-L617 PolarHBondContact O-N 2.85Å; E614-L618 HydrophobicContact CG-CD1 3.85Å; E614-L618 HydrophobicContact CG-CG 4.34Å; E614-L618 WeakPolarHBondContact O-CB 3.2Å; E614-L618 WeakPolarHBondContact O-CG 3.21Å; E614-L618 PolarHBondContact O-N 3.45Å; E614-Y703 HydrophobicContact CB-CE1 4.48Å
615Y92.3Very high92.7Very high103 Ų10354 Ų5440%0.40426%0.259SS..Hα-helixtrans-57.2-49175.3-176.1-95000112.3P611 L613 L617 L618 L619 E659P611-Y615 VanDerWaalsContact O-CB 3.32Å; P611-Y615 WeakPolarHBondContact O-CB 3.49Å; P611-Y615 PolarHBondContact O-N 2.95Å; L613-Y615 VanDerWaalsContact C-N 3.3Å; L613-Y615 PolarHBondContact O-N 2.94Å; Y615-L617 PolarHBondContact O-N 2.79Å; Y615-L618 PolarHBondContact O-N 3.16Å; Y615-L619 HydrophobicContact CE1-CD2 4.45Å; Y615-L619 WeakPolarHBondContact O-CB 3.45Å; Y615-L619 PolarHBondContact O-N 3.03Å; Y615-E659 PolarHBondContact OH-OE2 2.83Å
616Q91.4Very high92.6Very high25 Ų2554 Ų5412%0.11726%0.259CS..Hα-helixtrans-62.3-42.8179.6-63.6-54.7-41.200111.4K612 L613 E614 L619 A620 Q663 H666 L670K612-Q616 WeakPolarHBondContact O-CG 3.46Å; K612-Q616 PolarHBondContact O-N 3.41Å; L613-Q616 PolarHBondContact O-N 3.01Å; E614-Q616 PolarHBondContact O-N 2.65Å; Q616-L619 WeakPolarHBondContact O-CB 3.46Å; Q616-L619 PolarHBondContact O-N 2.79Å; Q616-A620 PolarHBondContact O-N 2.8Å; Q616-Q663 HydrophobicContact CB-CG 4.22Å; Q616-Q663 PolarHBondContact O-NE2 3.3Å; Q616-H666 HydrophobicContact CG-CB 4.44Å; Q616-L670 HydrophobicContact CG-CD1 4.15Å
617L89.5Confident92.4Very high35 Ų3558.1 Ų58.118%0.18328%0.281CS..Hα-helixtrans-67.2-39.1178.8-67.2172.6000112.4L613 E614 Y615 A620 K621 L667 Y703L613-L617 WeakPolarHBondContact O-CG 3.14Å; L613-L617 PolarHBondContact O-N 2.73Å; E614-L617 PolarHBondContact O-N 2.85Å; Y615-L617 PolarHBondContact O-N 2.79Å; L617-A620 PolarHBondContact O-N 2.8Å; L617-K621 PolarHBondContact O-N 2.89Å; L617-L667 HydrophobicContact CD2-CD1 4.04Å; L617-Y703 VanDerWaalsContact CD1-CB 3.46Å; L617-Y703 HydrophobicContact CD1-CD1 3.47Å; L617-Y703 VanDerWaalsContact CD1-CD1 3.47Å; L617-Y703 HydrophobicContact CD1-CD2 4.38Å; L617-Y703 HydrophobicContact CD1-CE1 4.25Å; L617-Y703 HydrophobicContact CD1-CG 3.51Å
618L90.4Very high92.3Very high80 Ų8054.9 Ų54.942%0.41928%0.276SS..Hα-helixtrans-65.7-38.7174.2-75.1172.3000111.9E614 Y615 A620 K621 K622E614-L618 HydrophobicContact CG-CD1 3.85Å; E614-L618 HydrophobicContact CG-CG 4.34Å; E614-L618 WeakPolarHBondContact O-CB 3.2Å; E614-L618 WeakPolarHBondContact O-CG 3.21Å; E614-L618 PolarHBondContact O-N 3.45Å; Y615-L618 PolarHBondContact O-N 3.16Å; L618-A620 VanDerWaalsContact C-N 3.34Å; L618-A620 PolarHBondContact O-N 3.15Å; L618-K621 PolarHBondContact O-N 3.16Å; L618-K622 WeakPolarHBondContact O-CG 3.02Å; L618-K622 PolarHBondContact O-N 3.41Å
619L92.4Very high92.1Very high5 Ų553 Ų533%0.02627%0.267CS..Hα-helixtrans-58.3-45.4176.2179.260.4000111.4Y615 Q616 K621 K622 V623 L656 E659 Y660 Q663Y615-L619 HydrophobicContact CE1-CD2 4.45Å; Y615-L619 WeakPolarHBondContact O-CB 3.45Å; Y615-L619 PolarHBondContact O-N 3.03Å; Q616-L619 WeakPolarHBondContact O-CB 3.46Å; Q616-L619 PolarHBondContact O-N 2.79Å; L619-K621 PolarHBondContact O-N 2.96Å; L619-K622 PolarHBondContact O-N 2.91Å; L619-V623 HydrophobicContact CD1-CG2 4.04Å; L619-V623 WeakPolarHBondContact O-CG2 3.28Å; L619-V623 PolarHBondContact O-N 3.36Å; L619-L656 HydrophobicContact CD1-CB 4.09Å; L619-L656 HydrophobicContact CD1-CD2 3.56Å; L619-L656 HydrophobicContact CD1-CG 4.44Å; L619-E659 HydrophobicContact CD1-CB 4.41Å; L619-E659 HydrophobicContact CD2-CB 3.8Å; L619-Y660 HydrophobicContact CG-CD2 4.42Å; L619-Q663 HydrophobicContact CD2-CB 4.05Å; L619-Q663 HydrophobicContact CD2-CG 4.14Å
620A90.5Very high91.9Very high16 Ų1655.8 Ų55.813%0.13228%0.279CS..Hα-helixtrans-56.5-48.4173.300000112.2Q616 L617 L618 K622 V623 Q624 Y660Q616-A620 PolarHBondContact O-N 2.8Å; L617-A620 PolarHBondContact O-N 2.8Å; L618-A620 VanDerWaalsContact C-N 3.34Å; L618-A620 PolarHBondContact O-N 3.15Å; A620-K622 PolarHBondContact O-N 3.35Å; A620-V623 PolarHBondContact O-N 2.88Å; A620-Q624 VanDerWaalsContact O-CG 3.31Å; A620-Q624 WeakPolarHBondContact O-CG 3.33Å; A620-Q624 PolarHBondContact O-N 2.96Å; A620-Y660 HydrophobicContact CB-CE2 3.95Å
621K90.4Very high91.7Very high132 Ų13259.9 Ų59.957%0.57430%0.298SS*.Hα-helixtrans-62.4-42.8-179.6-69.7176.7-178.5175.60112L617 L618 L619 L625L617-K621 PolarHBondContact O-N 2.89Å; L618-K621 PolarHBondContact O-N 3.16Å; L619-K621 PolarHBondContact O-N 2.96Å; K621-L625 WeakPolarHBondContact O-CG 3.09Å
622K92.6Very high91.5Very high71 Ų7159.8 Ų59.831%0.30929%0.293SS..Hα-helixtrans-62.4-46177.4-71.8-178.8176.2-174.40111.4L618 L619 A620 Q624 L625 I626 I649 L656L618-K622 WeakPolarHBondContact O-CG 3.02Å; L618-K622 PolarHBondContact O-N 3.41Å; L619-K622 PolarHBondContact O-N 2.91Å; A620-K622 PolarHBondContact O-N 3.35Å; K622-Q624 VanDerWaalsContact C-N 3.34Å; K622-Q624 PolarHBondContact O-N 2.75Å; K622-L625 WeakPolarHBondContact O-CB 3.17Å; K622-L625 PolarHBondContact O-N 3.37Å; K622-I626 PolarHBondContact O-N 2.92Å; K622-I649 HydrophobicContact CB-CD1 4.26Å; K622-I649 HydrophobicContact CB-CG1 4.44Å; K622-I649 HydrophobicContact CD-CG1 4.31Å; K622-I649 HydrophobicContact CG-CD1 3.91Å; K622-I649 HydrophobicContact CG-CG1 4.14Å; K622-L656 HydrophobicContact CB-CD1 4.24Å; K622-L656 HydrophobicContact CD-CD1 4.2Å; K622-L656 HydrophobicContact CD-CD2 4.23Å
623V92.8Very high91.2Very high13 Ų1360.3 Ų60.38%0.07930%0.296CS..Hα-helixtrans-66.9-35.6-176.9174.50000112L619 A620 L625 I626 L656 Y660L619-V623 HydrophobicContact CD1-CG2 4.04Å; L619-V623 WeakPolarHBondContact O-CG2 3.28Å; L619-V623 PolarHBondContact O-N 3.36Å; A620-V623 PolarHBondContact O-N 2.88Å; V623-L625 PolarHBondContact O-N 2.75Å; V623-L625 VanDerWaalsContact O-N 3.17Å; V623-I626 HydrophobicContact CB-CD1 4.32Å; V623-I626 HydrophobicContact CG1-CD1 4.48Å; V623-I626 HydrophobicContact CG2-CD1 4.09Å; V623-I626 PolarHBondContact O-N 3.4Å; V623-I626 VanDerWaalsContact O-N 3.14Å; V623-L656 HydrophobicContact CG2-CB 4.14Å; V623-Y660 HydrophobicContact CB-CD1 4.49Å; V623-Y660 HydrophobicContact CB-CD2 4.16Å; V623-Y660 HydrophobicContact CB-CG 4.11Å; V623-Y660 HydrophobicContact CG1-CD1 3.77Å; V623-Y660 HydrophobicContact CG1-CD2 4.32Å; V623-Y660 HydrophobicContact CG1-CE1 4.19Å; V623-Y660 HydrophobicContact CG1-CG 3.84Å; V623-Y660 HydrophobicContact CG2-CD2 4.05Å; V623-Y660 HydrophobicContact CG2-CG 3.92Å
624Q92.8Very high91Very high143 Ų14366.9 Ų66.967%0.66833%0.33SS*.Hα-helixtrans-58.5-25.8172.7-74.9174.35.300113.4A620 K622A620-Q624 VanDerWaalsContact O-CG 3.31Å; A620-Q624 WeakPolarHBondContact O-CG 3.33Å; A620-Q624 PolarHBondContact O-N 2.96Å; K622-Q624 VanDerWaalsContact C-N 3.34Å; K622-Q624 PolarHBondContact O-N 2.75Å
625L93.8Very high90.7Very high66 Ų6670 Ų7035%0.34635%0.345SS..Hα-helixtrans-89.6-19.3179.2-60.6174.8000113.3K621 K622 V623 D627 A628 L629 Y646 I649K621-L625 WeakPolarHBondContact O-CG 3.09Å; K622-L625 WeakPolarHBondContact O-CB 3.17Å; K622-L625 PolarHBondContact O-N 3.37Å; V623-L625 PolarHBondContact O-N 2.75Å; V623-L625 VanDerWaalsContact O-N 3.17Å; L625-D627 PolarHBondContact O-N 3.43Å; L625-A628 PolarHBondContact O-N 2.89Å; L625-L629 HydrophobicContact CB-CD1 4.06Å; L625-L629 HydrophobicContact CB-CG 4.45Å; L625-L629 WeakPolarHBondContact O-CB 3.47Å; L625-L629 VanDerWaalsContact O-CG 3.23Å; L625-L629 WeakPolarHBondContact O-CG 3.43Å; L625-L629 PolarHBondContact O-N 2.68Å; L625-Y646 HydrophobicContact CD1-CE1 3.89Å; L625-I649 HydrophobicContact CD1-CD1 4.44Å
626I93.2Very high90.1Very high0 Ų070.7 Ų70.70%035%0.351CS..Hα-helixtrans-57.5-48.5-171.7-72.5174.2000111.5K622 V623 A628 L629 K630 I649 A653 L656K622-I626 PolarHBondContact O-N 2.92Å; V623-I626 HydrophobicContact CB-CD1 4.32Å; V623-I626 HydrophobicContact CG1-CD1 4.48Å; V623-I626 HydrophobicContact CG2-CD1 4.09Å; V623-I626 PolarHBondContact O-N 3.4Å; V623-I626 VanDerWaalsContact O-N 3.14Å; I626-A628 PolarHBondContact O-N 3.21Å; I626-L629 PolarHBondContact O-N 3.09Å; I626-K630 HydrophobicContact CG2-CD 3.87Å; I626-K630 HydrophobicContact CG2-CG 4.25Å; I626-K630 WeakPolarHBondContact O-CB 3.43Å; I626-K630 WeakPolarHBondContact O-CG 3.39Å; I626-K630 PolarHBondContact O-N 3.36Å; I626-I649 HydrophobicContact CG1-CG2 3.78Å; I626-A653 HydrophobicContact CD1-CB 4.16Å; I626-A653 HydrophobicContact CG1-CB 4.33Å; I626-A653 HydrophobicContact CG2-CB 3.92Å; I626-L656 HydrophobicContact CD1-CB 4Å; I626-L656 HydrophobicContact CD1-CD1 4.4Å
627D91.3Very high89Confident96 Ų9672.8 Ų72.851%0.51338%0.38SS..Hα-helixtrans-63.7-45.8-175.2-66.9-21.2000111.1L625 L629 K630 E631L625-D627 PolarHBondContact O-N 3.43Å; D627-L629 VanDerWaalsContact C-N 3.34Å; D627-L629 PolarHBondContact O-N 3.22Å; D627-K630 PolarHBondContact O-N 3.29Å; D627-E631 WeakPolarHBondContact O-CG 3.35Å; D627-E631 PolarHBondContact O-N 2.89Å
628A92Very high88.1Confident51 Ų5175.1 Ų75.142%0.42139%0.393SS..Hα-helixtrans-63.3-38.7176.700000112.5L625 I626 L632L625-A628 PolarHBondContact O-N 2.89Å; I626-A628 PolarHBondContact O-N 3.21Å; A628-L632 WeakPolarHBondContact O-CG 3.47Å; A628-L632 PolarHBondContact O-N 2.86Å; A628-L632 VanDerWaalsContact O-N 3.09Å
629L90.1Very high87.3Confident9 Ų973.3 Ų73.35%0.04738%0.382CS..Hα-helixtrans-69.8-38.5176.9-69.6174.3000111.9L625 I626 D627 L632 Q633 L642 Y646 I649 L650L625-L629 HydrophobicContact CB-CD1 4.06Å; L625-L629 HydrophobicContact CB-CG 4.45Å; L625-L629 WeakPolarHBondContact O-CB 3.47Å; L625-L629 VanDerWaalsContact O-CG 3.23Å; L625-L629 WeakPolarHBondContact O-CG 3.43Å; L625-L629 PolarHBondContact O-N 2.68Å; I626-L629 PolarHBondContact O-N 3.09Å; D627-L629 VanDerWaalsContact C-N 3.34Å; D627-L629 PolarHBondContact O-N 3.22Å; L629-L632 HydrophobicContact CD2-CD1 4.48Å; L629-L632 PolarHBondContact O-N 3.31Å; L629-Q633 WeakPolarHBondContact O-CB 3.4Å; L629-Q633 PolarHBondContact O-N 3.34Å; L629-L642 HydrophobicContact CD2-CD1 4.43Å; L629-L642 HydrophobicContact CD2-CD2 3.9Å; L629-Y646 HydrophobicContact CD1-CD1 4.37Å; L629-Y646 HydrophobicContact CD1-CG 4.15Å; L629-Y646 HydrophobicContact CD2-CD2 3.93Å; L629-Y646 HydrophobicContact CD2-CG 3.98Å; L629-I649 HydrophobicContact CD1-CB 4.28Å; L629-I649 HydrophobicContact CD1-CG2 4.06Å; L629-L650 HydrophobicContact CB-CD1 3.99Å; L629-L650 HydrophobicContact CB-CD2 3.64Å; L629-L650 HydrophobicContact CB-CG 3.76Å; L629-L650 HydrophobicContact CD1-CG 4.4Å
630K90.3Very high86.7Confident61 Ų6178.5 Ų78.527%0.26541%0.41SS..Hα-helixtrans-64.8-41175.4-79.7-177.3173.71770110.6I626 D627 Q633 I634 L650 D654I626-K630 HydrophobicContact CG2-CD 3.87Å; I626-K630 HydrophobicContact CG2-CG 4.25Å; I626-K630 WeakPolarHBondContact O-CB 3.43Å; I626-K630 WeakPolarHBondContact O-CG 3.39Å; I626-K630 PolarHBondContact O-N 3.36Å; D627-K630 PolarHBondContact O-N 3.29Å; K630-Q633 PolarHBondContact O-N 2.92Å; K630-I634 WeakPolarHBondContact O-CD1 3.41Å; K630-I634 VanDerWaalsContact O-CG1 3.26Å; K630-I634 WeakPolarHBondContact O-CG1 3.47Å; K630-I634 PolarHBondContact O-N 3.05Å; K630-L650 HydrophobicContact CG-CD2 3.78Å; K630-D654 IonicContact NZ-OD1 3.73Å; K630-D654 PolarHBondContact NZ-OD1 2.92Å
631E90.6Very high86.3Confident123 Ų12381.8 Ų81.858%0.57542%0.422SS*.Hα-helixtrans-59-49173.1-75-178.5177.900111.8D627 Q633 I634 H635D627-E631 WeakPolarHBondContact O-CG 3.35Å; D627-E631 PolarHBondContact O-N 2.89Å; E631-Q633 VanDerWaalsContact C-N 3.32Å; E631-Q633 PolarHBondContact O-N 3.21Å; E631-I634 PolarHBondContact O-N 3.3Å; E631-H635 PolarHBondContact O-CD2 3.04Å; E631-H635 PolarHBondContact O-N 3.05Å; E631-H635 VanDerWaalsContact O-N 3.07Å
632L88.4Confident86.1Confident70 Ų7076 Ų7637%0.36640%0.397SS..Hα-helixtrans-59.4-40.5176.8-77.2166.4000112.6A628 L629 H635 E636 F641A628-L632 WeakPolarHBondContact O-CG 3.47Å; A628-L632 PolarHBondContact O-N 2.86Å; A628-L632 VanDerWaalsContact O-N 3.09Å; L629-L632 HydrophobicContact CD2-CD1 4.48Å; L629-L632 PolarHBondContact O-N 3.31Å; L632-H635 PolarHBondContact O-N 3.13Å; L632-E636 PolarHBondContact O-N 2.72Å; L632-F641 HydrophobicContact CB-CE2 4.44Å; L632-F641 HydrophobicContact CB-CZ 4.11Å; L632-F641 HydrophobicContact CD2-CE2 4.48Å
633Q86.3Confident86.1Confident76 Ų7676.8 Ų76.836%0.35540%0.404SS..Hα-helixtrans-63.2-41.3177-174.1-178.916.500112.1L629 K630 E631 H635 G637 M639 L650L629-Q633 WeakPolarHBondContact O-CB 3.4Å; L629-Q633 PolarHBondContact O-N 3.34Å; K630-Q633 PolarHBondContact O-N 2.92Å; E631-Q633 VanDerWaalsContact C-N 3.32Å; E631-Q633 PolarHBondContact O-N 3.21Å; Q633-H635 VanDerWaalsContact C-N 3.34Å; Q633-G637 PolarHBondContact O-N 2.56Å; Q633-M639 HydrophobicContact CG-CG 4.44Å; Q633-L650 HydrophobicContact CB-CD1 4.41Å
634I88.4Confident85.9Confident139 Ų13980.6 Ų80.671%0.71343%0.429SS*.Hα-helixtrans-65.3-39.3178-68.1163.6000110.8K630 E631K630-I634 WeakPolarHBondContact O-CD1 3.41Å; K630-I634 VanDerWaalsContact O-CG1 3.26Å; K630-I634 WeakPolarHBondContact O-CG1 3.47Å; K630-I634 PolarHBondContact O-N 3.05Å; E631-I634 PolarHBondContact O-N 3.3Å
635H84.3Confident85.8Confident157 Ų15779.8 Ų79.873%0.72743%0.425SS*.Hα-helixtrans-75.1-43.3-177.5-77.6-62.2000114E631 L632 Q633E631-H635 PolarHBondContact O-CD2 3.04Å; E631-H635 PolarHBondContact O-N 3.05Å; E631-H635 VanDerWaalsContact O-N 3.07Å; L632-H635 PolarHBondContact O-N 3.13Å; Q633-H635 VanDerWaalsContact C-N 3.34Å
636E80.3Confident85.6Confident116 Ų11680.6 Ų80.654%0.54242%0.424SS..Hα-helixtrans-97.8-13.9-171.9-65-151.9-171.600114L632 N638 F641L632-E636 PolarHBondContact O-N 2.72Å; E636-N638 PolarHBondContact O-N 2.9Å; E636-F641 HydrophobicContact CB-CD1 4.24Å; E636-F641 HydrophobicContact CB-CE1 3.53Å; E636-F641 HydrophobicContact CB-CZ 4.07Å; E636-F641 HydrophobicContact CG-CE1 4.02Å; E636-F641 HydrophobicContact CG-CZ 4.17Å; E636-F641 WeakPolarHBondContact OE2-CD1 3.43Å; E636-F641 WeakPolarHBondContact OE2-CE1 3.31Å
637G69.1Low85.4Confident70 Ų7083.9 Ų83.972%0.72244%0.437SS*.SBendtrans66.3-1417400000116.2Q633Q633-G637 PolarHBondContact O-N 2.56Å
638N69.6Low85.4Confident83 Ų8382.3 Ų82.344%0.44443%0.432SS..  trans-132.7130179.4-175.5-8.1000110.8E636 N640 F641E636-N638 PolarHBondContact O-N 2.9Å; N638-N640 VanDerWaalsContact C-N 3.25Å; N638-N640 PolarHBondContact ND2-ND2 2.96Å; N638-N640 PolarHBondContact O-N 3.28Å; N638-N640 WeakPolarHBondContact OD1-CB 3.22Å; N638-N640 PolarHBondContact OD1-N 2.83Å; N638-N640 PolarHBondContact OD1-ND2 3.37Å; N638-N640 PolarHBondContact OD1-OD1 3.09Å; N638-F641 WeakPolarHBondContact O-CD1 3.4Å; N638-F641 WeakPolarHBondContact O-CE1 3.23Å
639M73.9Confident85.3Confident42 Ų4280.1 Ų80.121%0.20741%0.413CS..G310 helixtrans-80.30.9-177.1-60.2172.275.200114.1Q633 F641 L642 R647 L650Q633-M639 HydrophobicContact CG-CG 4.44Å; M639-F641 PolarHBondContact O-N 2.83Å; M639-F641 VanDerWaalsContact O-N 3.13Å; M639-L642 PolarHBondContact O-N 3.12Å; M639-R647 HydrophobicContact CB-CG 4.37Å; M639-R647 HydrophobicContact CE-CB 3.94Å; M639-R647 HydrophobicContact CE-CG 4.05Å; M639-R647 PolarHBondContact O-NE 2.96Å; M639-R647 PolarHBondContact O-NH2 2.75Å; M639-L650 HydrophobicContact CE-CB 3.81Å; M639-L650 HydrophobicContact CE-CD1 3.71Å; M639-L650 HydrophobicContact CE-CG 4.43Å
640N79.2Confident85.3Confident114 Ų11480.4 Ų80.461%0.6142%0.415SS*.G310 helixtrans-62.4-20.6-173-73.7-12.2000115.2N638 R647N638-N640 VanDerWaalsContact C-N 3.25Å; N638-N640 PolarHBondContact ND2-ND2 2.96Å; N638-N640 PolarHBondContact O-N 3.28Å; N638-N640 WeakPolarHBondContact OD1-CB 3.22Å; N638-N640 PolarHBondContact OD1-N 2.83Å; N638-N640 PolarHBondContact OD1-ND2 3.37Å; N638-N640 PolarHBondContact OD1-OD1 3.09Å; N640-R647 VanDerWaalsContact CA-NH2 3.3Å; N640-R647 PolarHBondContact O-NH2 3.36Å
641F83.8Confident85.3Confident86 Ų8684.5 Ų84.538%0.37744%0.435SS..G310 helixtrans-83.8-21.1176.269.9-86.1000113.3L632 E636 N638 M639L632-F641 HydrophobicContact CB-CE2 4.44Å; L632-F641 HydrophobicContact CB-CZ 4.11Å; L632-F641 HydrophobicContact CD2-CE2 4.48Å; E636-F641 HydrophobicContact CB-CD1 4.24Å; E636-F641 HydrophobicContact CB-CE1 3.53Å; E636-F641 HydrophobicContact CB-CZ 4.07Å; E636-F641 HydrophobicContact CG-CE1 4.02Å; E636-F641 HydrophobicContact CG-CZ 4.17Å; E636-F641 WeakPolarHBondContact OE2-CD1 3.43Å; E636-F641 WeakPolarHBondContact OE2-CE1 3.31Å; N638-F641 WeakPolarHBondContact O-CD1 3.4Å; N638-F641 WeakPolarHBondContact O-CE1 3.23Å; M639-F641 PolarHBondContact O-N 2.83Å; M639-F641 VanDerWaalsContact O-N 3.13Å
642L86.2Confident85.4Confident11 Ų1183.3 Ų83.36%0.05843%0.429CS..SBendtrans-76.8142.6177.9-67.6174.7000110.4L629 M639 Y646 R647 L650L629-L642 HydrophobicContact CD2-CD1 4.43Å; L629-L642 HydrophobicContact CD2-CD2 3.9Å; M639-L642 PolarHBondContact O-N 3.12Å; L642-Y646 HydrophobicContact CD2-CD2 4.45Å; L642-R647 HydrophobicContact CB-CG 3.95Å; L642-R647 VanDerWaalsContact O-CZ 3.22Å; L642-R647 PolarHBondContact O-NE 3.37Å; L642-R647 PolarHBondContact O-NH2 3.46Å; L642-L650 HydrophobicContact CD1-CD1 3.55Å
643I91.8Very high85.5Confident86 Ų8680.1 Ų80.144%0.44141%0.413SS..  trans-65.7152.2170.159.6171000110.6E645 Y646 R647I643-E645 HydrophobicContact CD1-CB 4.26Å; I643-E645 HydrophobicContact CG1-CB 4.46Å; I643-E645 PolarHBondContact O-N 2.96Å; I643-E645 VanDerWaalsContact O-N 3.14Å; I643-Y646 HydrophobicContact CD1-CD1 4.36Å; I643-Y646 HydrophobicContact CD1-CD2 4.04Å; I643-Y646 HydrophobicContact CD1-CE1 4.32Å; I643-Y646 HydrophobicContact CD1-CE2 4Å; I643-Y646 HydrophobicContact CD1-CG 4.23Å; I643-Y646 HydrophobicContact CG1-CD1 4.4Å; I643-Y646 HydrophobicContact CG1-CD2 3.67Å; I643-Y646 HydrophobicContact CG1-CE2 4.12Å; I643-Y646 HydrophobicContact CG1-CG 3.83Å; I643-Y646 PolarHBondContact O-N 2.94Å; I643-Y646 VanDerWaalsContact O-N 3.12Å; I643-R647 PolarHBondContact O-N 2.91Å
644P89.6Confident85.7Confident94 Ų9482.3 Ų82.361%0.6143%0.427SS*.Hα-helixtrans-54-36.3-176.3-27.835.3000114.4Y646 R647 C648P644-Y646 PolarHBondContact O-N 2.92Å; P644-R647 WeakPolarHBondContact O-CB 3.36Å; P644-R647 PolarHBondContact O-N 2.76Å; P644-C648 PolarHBondContact O-N 2.93Å; P644-C648 PolarHBondContact O-SG 3.35Å
645E89.4Confident85.8Confident126 Ų12680.5 Ų80.559%0.58942%0.416SS*.Hα-helixtrans-58.6-46.4178.3-176.1176.7-175.600112.5I643 R647 C648 I649I643-E645 HydrophobicContact CD1-CB 4.26Å; I643-E645 HydrophobicContact CG1-CB 4.46Å; I643-E645 PolarHBondContact O-N 2.96Å; I643-E645 VanDerWaalsContact O-N 3.14Å; E645-R647 VanDerWaalsContact C-N 3.33Å; E645-R647 PolarHBondContact O-N 2.79Å; E645-C648 WeakPolarHBondContact O-CB 3.41Å; E645-C648 PolarHBondContact O-N 2.77Å; E645-I649 WeakPolarHBondContact O-CG1 3.48Å; E645-I649 PolarHBondContact O-N 2.97Å; E645-I649 VanDerWaalsContact O-N 3.12Å
646Y90.9Very high86.2Confident83 Ų8373.2 Ų73.233%0.32538%0.382SS..Hα-helixtrans-72.3-27.9178.3-66-14.7000112.8L625 L629 L642 I643 P644 I649 L650L625-Y646 HydrophobicContact CD1-CE1 3.89Å; L629-Y646 HydrophobicContact CD1-CD1 4.37Å; L629-Y646 HydrophobicContact CD1-CG 4.15Å; L629-Y646 HydrophobicContact CD2-CD2 3.93Å; L629-Y646 HydrophobicContact CD2-CG 3.98Å; L642-Y646 HydrophobicContact CD2-CD2 4.45Å; I643-Y646 HydrophobicContact CD1-CD1 4.36Å; I643-Y646 HydrophobicContact CD1-CD2 4.04Å; I643-Y646 HydrophobicContact CD1-CE1 4.32Å; I643-Y646 HydrophobicContact CD1-CE2 4Å; I643-Y646 HydrophobicContact CD1-CG 4.23Å; I643-Y646 HydrophobicContact CG1-CD1 4.4Å; I643-Y646 HydrophobicContact CG1-CD2 3.67Å; I643-Y646 HydrophobicContact CG1-CE2 4.12Å; I643-Y646 HydrophobicContact CG1-CG 3.83Å; I643-Y646 PolarHBondContact O-N 2.94Å; I643-Y646 VanDerWaalsContact O-N 3.12Å; P644-Y646 PolarHBondContact O-N 2.92Å; Y646-I649 HydrophobicContact CD1-CD1 4.09Å; Y646-I649 PolarHBondContact O-N 2.66Å; Y646-L650 PolarHBondContact O-N 2.93Å
647R88.4Confident86.7Confident69 Ų6971 Ų7126%0.2637%0.371SS..Hα-helixtrans-65.6-43.6171.1-59.6-174.1-163172.45.3111M639 N640 L642 I643 P644 E645 I649 L650 E651M639-R647 HydrophobicContact CB-CG 4.37Å; M639-R647 HydrophobicContact CE-CB 3.94Å; M639-R647 HydrophobicContact CE-CG 4.05Å; M639-R647 PolarHBondContact O-NE 2.96Å; M639-R647 PolarHBondContact O-NH2 2.75Å; N640-R647 VanDerWaalsContact CA-NH2 3.3Å; N640-R647 PolarHBondContact O-NH2 3.36Å; L642-R647 HydrophobicContact CB-CG 3.95Å; L642-R647 VanDerWaalsContact O-CZ 3.22Å; L642-R647 PolarHBondContact O-NE 3.37Å; L642-R647 PolarHBondContact O-NH2 3.46Å; I643-R647 PolarHBondContact O-N 2.91Å; P644-R647 WeakPolarHBondContact O-CB 3.36Å; P644-R647 PolarHBondContact O-N 2.76Å; E645-R647 VanDerWaalsContact C-N 3.33Å; E645-R647 PolarHBondContact O-N 2.79Å; R647-I649 VanDerWaalsContact C-N 3.31Å; R647-I649 PolarHBondContact O-N 3.32Å; R647-L650 WeakPolarHBondContact O-CB 3.28Å; R647-L650 PolarHBondContact O-N 2.89Å; R647-L650 VanDerWaalsContact O-N 3.12Å; R647-E651 WeakPolarHBondContact O-CG 3.24Å; R647-E651 PolarHBondContact O-N 3.45Å
648C90.1Very high87.6Confident62 Ų6272.2 Ų72.242%0.41936%0.358SS..Hα-helixtrans-59.9-42.5175.5-60.50000111.2P644 E645 L650 E651 E652P644-C648 PolarHBondContact O-N 2.93Å; P644-C648 PolarHBondContact O-SG 3.35Å; E645-C648 WeakPolarHBondContact O-CB 3.41Å; E645-C648 PolarHBondContact O-N 2.77Å; C648-L650 VanDerWaalsContact C-N 3.31Å; C648-L650 PolarHBondContact O-N 2.91Å; C648-E651 PolarHBondContact O-N 3.48Å; C648-E652 PolarHBondContact O-N 2.86Å
649I91.7Very high88.5Confident6 Ų670.9 Ų70.93%0.03135%0.35CS..Hα-helixtrans-60.9-40.3175.6-65.6172.7000111.5K622 L625 I626 L629 E645 Y646 R647 E652 A653 L656K622-I649 HydrophobicContact CB-CD1 4.26Å; K622-I649 HydrophobicContact CB-CG1 4.44Å; K622-I649 HydrophobicContact CD-CG1 4.31Å; K622-I649 HydrophobicContact CG-CD1 3.91Å; K622-I649 HydrophobicContact CG-CG1 4.14Å; L625-I649 HydrophobicContact CD1-CD1 4.44Å; I626-I649 HydrophobicContact CG1-CG2 3.78Å; L629-I649 HydrophobicContact CD1-CB 4.28Å; L629-I649 HydrophobicContact CD1-CG2 4.06Å; E645-I649 WeakPolarHBondContact O-CG1 3.48Å; E645-I649 PolarHBondContact O-N 2.97Å; E645-I649 VanDerWaalsContact O-N 3.12Å; Y646-I649 HydrophobicContact CD1-CD1 4.09Å; Y646-I649 PolarHBondContact O-N 2.66Å; R647-I649 VanDerWaalsContact C-N 3.31Å; R647-I649 PolarHBondContact O-N 3.32Å; I649-E652 CarbonylContact O-C 3.55Å; I649-A653 VanDerWaalsContact O-CA 3.29Å; I649-A653 WeakPolarHBondContact O-CA 3.37Å; I649-A653 WeakPolarHBondContact O-CB 3.28Å; I649-A653 PolarHBondContact O-N 2.85Å; I649-L656 HydrophobicContact CG2-CD1 4.16Å
650L88.7Confident89.3Confident15 Ų1572.8 Ų72.88%0.07936%0.355CS..Hα-helixtrans-68.1-41.1177-82.5174.4000112.7L629 K630 Q633 M639 L642 Y646 R647 C648 E652 A653L629-L650 HydrophobicContact CB-CD1 3.99Å; L629-L650 HydrophobicContact CB-CD2 3.64Å; L629-L650 HydrophobicContact CB-CG 3.76Å; L629-L650 HydrophobicContact CD1-CG 4.4Å; K630-L650 HydrophobicContact CG-CD2 3.78Å; Q633-L650 HydrophobicContact CB-CD1 4.41Å; M639-L650 HydrophobicContact CE-CB 3.81Å; M639-L650 HydrophobicContact CE-CD1 3.71Å; M639-L650 HydrophobicContact CE-CG 4.43Å; L642-L650 HydrophobicContact CD1-CD1 3.55Å; Y646-L650 PolarHBondContact O-N 2.93Å; R647-L650 WeakPolarHBondContact O-CB 3.28Å; R647-L650 PolarHBondContact O-N 2.89Å; R647-L650 VanDerWaalsContact O-N 3.12Å; C648-L650 VanDerWaalsContact C-N 3.31Å; C648-L650 PolarHBondContact O-N 2.91Å; L650-E652 VanDerWaalsContact C-N 3.31Å; L650-E652 PolarHBondContact O-N 2.93Å; L650-A653 WeakPolarHBondContact O-CB 3.36Å; L650-A653 PolarHBondContact O-N 3.5Å
651E90Very high89.7Confident146 Ų14675.2 Ų75.268%0.68236%0.36SS*.Hα-helixtrans-63-38.1176.8-72.6168.7-166.500111.7R647 C648R647-E651 WeakPolarHBondContact O-CG 3.24Å; R647-E651 PolarHBondContact O-N 3.45Å; C648-E651 PolarHBondContact O-N 3.48Å
652E92.3Very high89.8Confident99 Ų9976.3 Ų76.346%0.46337%0.365SS..THydrogen-bonded Turntrans-95.48.7179.6-64-178.4172.200113.9C648 I649 L650 D654 H655 L656C648-E652 PolarHBondContact O-N 2.86Å; I649-E652 CarbonylContact O-C 3.55Å; L650-E652 VanDerWaalsContact C-N 3.31Å; L650-E652 PolarHBondContact O-N 2.93Å; E652-D654 VanDerWaalsContact C-N 3.32Å; E652-D654 PolarHBondContact O-N 2.95Å; E652-H655 PolarHBondContact O-N 3.21Å; E652-H655 VanDerWaalsContact O-N 3.1Å; E652-L656 HydrophobicContact CB-CD1 4.16Å; E652-L656 HydrophobicContact CB-CG 4.2Å; E652-L656 WeakPolarHBondContact O-CG 3.39Å; E652-L656 PolarHBondContact O-N 3.26Å
653A91.4Very high89.9Confident2 Ų276.2 Ų76.22%0.01736%0.364CS..Hα-helixtrans-55.8-43.9-16700000113.4I626 I649 L650 L656 Q657I626-A653 HydrophobicContact CD1-CB 4.16Å; I626-A653 HydrophobicContact CG1-CB 4.33Å; I626-A653 HydrophobicContact CG2-CB 3.92Å; I649-A653 VanDerWaalsContact O-CA 3.29Å; I649-A653 WeakPolarHBondContact O-CA 3.37Å; I649-A653 WeakPolarHBondContact O-CB 3.28Å; I649-A653 PolarHBondContact O-N 2.85Å; L650-A653 WeakPolarHBondContact O-CB 3.36Å; L650-A653 PolarHBondContact O-N 3.5Å; A653-L656 PolarHBondContact O-N 3.45Å; A653-Q657 VanDerWaalsContact O-CB 3.28Å; A653-Q657 WeakPolarHBondContact O-CB 3.22Å; A653-Q657 PolarHBondContact O-N 2.94Å
654D90.9Very high89.7Confident123 Ų12375.7 Ų75.766%0.65837%0.366SS*.Hα-helixtrans-67.6-38.6-177.3-63.3-19.4000111.5K630 E652 E658K630-D654 IonicContact NZ-OD1 3.73Å; K630-D654 PolarHBondContact NZ-OD1 2.92Å; E652-D654 VanDerWaalsContact C-N 3.32Å; E652-D654 PolarHBondContact O-N 2.95Å; D654-E658 PolarHBondContact O-N 3.38Å
655H90.8Very high89.5Confident101 Ų10172.9 Ų72.947%0.46835%0.351SS..Hα-helixtrans-65.8-48.7175.2178.1-91.6000111.5E652 Q657 E658 E659E652-H655 PolarHBondContact O-N 3.21Å; E652-H655 VanDerWaalsContact O-N 3.1Å; H655-Q657 VanDerWaalsContact C-N 3.28Å; H655-Q657 PolarHBondContact O-N 3.5Å; H655-E658 PolarHBondContact O-N 3.24Å; H655-E658 VanDerWaalsContact O-N 3.17Å; H655-E659 IonicContact CE1-OE1 2.73Å; H655-E659 PolarHBondContact CE1-OE1 3.44Å; H655-E659 IonicContact CE1-OE2 2.81Å; H655-E659 IonicContact NE2-OE1 3.99Å; H655-E659 PolarHBondContact O-N 2.88Å
656L91.8Very high89.3Confident4 Ų469 Ų692%0.02133%0.333CS..Hα-helixtrans-59.5-40.5178.4-67.7171.8000111.4L619 K622 V623 I626 I649 E652 A653 E659 Y660L619-L656 HydrophobicContact CD1-CB 4.09Å; L619-L656 HydrophobicContact CD1-CD2 3.56Å; L619-L656 HydrophobicContact CD1-CG 4.44Å; K622-L656 HydrophobicContact CB-CD1 4.24Å; K622-L656 HydrophobicContact CD-CD1 4.2Å; K622-L656 HydrophobicContact CD-CD2 4.23Å; V623-L656 HydrophobicContact CG2-CB 4.14Å; I626-L656 HydrophobicContact CD1-CB 4Å; I626-L656 HydrophobicContact CD1-CD1 4.4Å; I649-L656 HydrophobicContact CG2-CD1 4.16Å; E652-L656 HydrophobicContact CB-CD1 4.16Å; E652-L656 HydrophobicContact CB-CG 4.2Å; E652-L656 WeakPolarHBondContact O-CG 3.39Å; E652-L656 PolarHBondContact O-N 3.26Å; A653-L656 PolarHBondContact O-N 3.45Å; L656-E659 PolarHBondContact O-N 3.4Å; L656-Y660 VanDerWaalsContact O-CB 3.29Å; L656-Y660 WeakPolarHBondContact O-CB 3.28Å; L656-Y660 PolarHBondContact O-N 3.04Å
657Q91.4Very high89.2Confident68 Ų6866.5 Ų66.532%0.31833%0.325SS..Hα-helixtrans-71.8-30.5179.5-159.9153.122.500112.3A653 H655A653-Q657 VanDerWaalsContact O-CB 3.28Å; A653-Q657 WeakPolarHBondContact O-CB 3.22Å; A653-Q657 PolarHBondContact O-N 2.94Å; H655-Q657 VanDerWaalsContact C-N 3.28Å; H655-Q657 PolarHBondContact O-N 3.5Å
658E88.1Confident89.3Confident96 Ų9670.1 Ų70.145%0.44935%0.345SS..Hα-helixtrans-68.8-45.8170.8-165.1-169.7146.900112.1D654 H655 Y660 K661 K662D654-E658 PolarHBondContact O-N 3.38Å; H655-E658 PolarHBondContact O-N 3.24Å; H655-E658 VanDerWaalsContact O-N 3.17Å; E658-Y660 VanDerWaalsContact C-N 3.32Å; E658-Y660 PolarHBondContact O-N 3.29Å; E658-K661 WeakPolarHBondContact O-CB 3.36Å; E658-K661 PolarHBondContact O-N 3.1Å; E658-K662 IonicContact OE1-NZ 3.67Å
659E87.6Confident89.2Confident56 Ų5668.4 Ų68.426%0.26233%0.33SS..Hα-helixtrans-63.6-38.3176.6-71.9-160146.200112.2Y615 L619 H655 L656 K661 K662 Q663Y615-E659 PolarHBondContact OH-OE2 2.83Å; L619-E659 HydrophobicContact CD1-CB 4.41Å; L619-E659 HydrophobicContact CD2-CB 3.8Å; H655-E659 IonicContact CE1-OE1 2.73Å; H655-E659 PolarHBondContact CE1-OE1 3.44Å; H655-E659 IonicContact CE1-OE2 2.81Å; H655-E659 IonicContact NE2-OE1 3.99Å; H655-E659 PolarHBondContact O-N 2.88Å; L656-E659 PolarHBondContact O-N 3.4Å; E659-K661 PolarHBondContact O-N 3.03Å; E659-K662 WeakPolarHBondContact O-CA 3.46Å; E659-K662 WeakPolarHBondContact O-CB 3.35Å; E659-K662 PolarHBondContact O-N 3.12Å; E659-Q663 PolarHBondContact O-N 3.29Å; E659-Q663 VanDerWaalsContact O-N 3.14Å
660Y91.3Very high89.2Confident81 Ų8168.3 Ų68.332%0.31833%0.329SS..Hα-helixtrans-60.5-28.8179.4-171.3-109.1000113.2L619 A620 V623 L656 E658 K662 Q663 P664L619-Y660 HydrophobicContact CG-CD2 4.42Å; A620-Y660 HydrophobicContact CB-CE2 3.95Å; V623-Y660 HydrophobicContact CB-CD1 4.49Å; V623-Y660 HydrophobicContact CB-CD2 4.16Å; V623-Y660 HydrophobicContact CB-CG 4.11Å; V623-Y660 HydrophobicContact CG1-CD1 3.77Å; V623-Y660 HydrophobicContact CG1-CD2 4.32Å; V623-Y660 HydrophobicContact CG1-CE1 4.19Å; V623-Y660 HydrophobicContact CG1-CG 3.84Å; V623-Y660 HydrophobicContact CG2-CD2 4.05Å; V623-Y660 HydrophobicContact CG2-CG 3.92Å; L656-Y660 VanDerWaalsContact O-CB 3.29Å; L656-Y660 WeakPolarHBondContact O-CB 3.28Å; L656-Y660 PolarHBondContact O-N 3.04Å; E658-Y660 VanDerWaalsContact C-N 3.32Å; E658-Y660 PolarHBondContact O-N 3.29Å; Y660-K662 PolarHBondContact O-N 3.07Å; Y660-Q663 HydrophobicContact CD2-CB 4.2Å; Y660-Q663 HydrophobicContact CD2-CG 4.4Å; Y660-Q663 WeakPolarHBondContact O-CB 3.42Å; Y660-Q663 PolarHBondContact O-N 3.44Å; Y660-P664 VanDerWaalsContact O-CD 3.24Å; Y660-P664 WeakPolarHBondContact O-CD 3.26Å
661K88.1Confident89.5Confident166 Ų16669 Ų6972%0.72233%0.33SS*.THydrogen-bonded Turntrans-60.5-29.6173.2-65.7172.2-174.2174.40112.4E658 E659E658-K661 WeakPolarHBondContact O-CB 3.36Å; E658-K661 PolarHBondContact O-N 3.1Å; E659-K661 PolarHBondContact O-N 3.03Å
662K84.5Confident89.5Confident108 Ų10863.5 Ų63.547%0.4731%0.313SS..THydrogen-bonded Turntrans-93.2-20.1-178.8-60.2166.3-174.3157.40112E658 E659 Y660 A665 H666E658-K662 IonicContact OE1-NZ 3.67Å; E659-K662 WeakPolarHBondContact O-CA 3.46Å; E659-K662 WeakPolarHBondContact O-CB 3.35Å; E659-K662 PolarHBondContact O-N 3.12Å; Y660-K662 PolarHBondContact O-N 3.07Å; K662-A665 PolarHBondContact O-N 3.16Å; K662-H666 PolarHBondContact O-CD2 3.32Å; K662-H666 PolarHBondContact O-N 3.29Å
663Q89.6Confident89.6Confident10 Ų1060.2 Ų60.25%0.04730%0.298CS..Hα-helixtrans-57.5-45.2-172.2-178-12327.900114.8Q616 L619 E659 Y660 A665 H666 L667Q616-Q663 HydrophobicContact CB-CG 4.22Å; Q616-Q663 PolarHBondContact O-NE2 3.3Å; L619-Q663 HydrophobicContact CD2-CB 4.05Å; L619-Q663 HydrophobicContact CD2-CG 4.14Å; E659-Q663 PolarHBondContact O-N 3.29Å; E659-Q663 VanDerWaalsContact O-N 3.14Å; Y660-Q663 HydrophobicContact CD2-CB 4.2Å; Y660-Q663 HydrophobicContact CD2-CG 4.4Å; Y660-Q663 WeakPolarHBondContact O-CB 3.42Å; Y660-Q663 PolarHBondContact O-N 3.44Å; Q663-A665 VanDerWaalsContact C-N 3.28Å; Q663-A665 PolarHBondContact O-N 3.19Å; Q663-H666 PolarHBondContact O-N 3.04Å; Q663-L667 WeakPolarHBondContact O-CB 3.47Å; Q663-L667 PolarHBondContact O-N 3.38Å
664P86.9Confident89.7Confident74 Ų7460.1 Ų60.148%0.48130%0.298SS..Hα-helixtrans-55.2-43.6-178.9-28.234.9000113.1Y660 H666 L667 E668Y660-P664 VanDerWaalsContact O-CD 3.24Å; Y660-P664 WeakPolarHBondContact O-CD 3.26Å; P664-H666 PolarHBondContact O-N 3.21Å; P664-L667 PolarHBondContact O-N 3.1Å; P664-E668 WeakPolarHBondContact O-CB 3.49Å; P664-E668 PolarHBondContact O-N 3.35Å
665A85.1Confident89.9Confident36 Ų3655.1 Ų55.130%0.29827%0.272SS..Hα-helixtrans-72.1-30.3-179.400000112.7K662 Q663 R669K662-A665 PolarHBondContact O-N 3.16Å; Q663-A665 VanDerWaalsContact C-N 3.28Å; Q663-A665 PolarHBondContact O-N 3.19Å; A665-R669 WeakPolarHBondContact O-CB 3.39Å; A665-R669 PolarHBondContact O-N 3.07Å
666H85.7Confident90.1Very high43 Ų4353.8 Ų53.820%0.19927%0.268CS..Hα-helixtrans-69.3-40.9172.1-74.5-63.5000111.9Q616 K662 Q663 P664 R669 L670Q616-H666 HydrophobicContact CG-CB 4.44Å; K662-H666 PolarHBondContact O-CD2 3.32Å; K662-H666 PolarHBondContact O-N 3.29Å; Q663-H666 PolarHBondContact O-N 3.04Å; P664-H666 PolarHBondContact O-N 3.21Å; H666-R669 PolarHBondContact O-N 2.72Å; H666-L670 WeakPolarHBondContact O-CG 3.42Å; H666-L670 PolarHBondContact O-N 3.05Å
667L89.4Confident90.2Very high31 Ų3153.8 Ų53.816%0.16227%0.268CS..Hα-helixtrans-69.2-45.7-179.3-169.3153.9000111.2L617 Q663 P664 R669 L670 Y671L617-L667 HydrophobicContact CD2-CD1 4.04Å; Q663-L667 WeakPolarHBondContact O-CB 3.47Å; Q663-L667 PolarHBondContact O-N 3.38Å; P664-L667 PolarHBondContact O-N 3.1Å; L667-R669 VanDerWaalsContact C-N 3.29Å; L667-R669 PolarHBondContact O-N 2.74Å; L667-L670 PolarHBondContact O-N 2.78Å; L667-L670 VanDerWaalsContact O-N 3.15Å; L667-Y671 HydrophobicContact CD2-CD1 3.97Å; L667-Y671 HydrophobicContact CD2-CD2 3.85Å; L667-Y671 HydrophobicContact CD2-CE1 3.58Å; L667-Y671 HydrophobicContact CD2-CE2 3.47Å; L667-Y671 VanDerWaalsContact CD2-CE2 3.47Å; L667-Y671 HydrophobicContact CD2-CG 4.1Å; L667-Y671 HydrophobicContact CG-CD1 4.45Å; L667-Y671 HydrophobicContact CG-CE1 4Å; L667-Y671 WeakPolarHBondContact O-CD1 3.26Å; L667-Y671 PolarHBondContact O-N 3.04Å
668E88.9Confident90.4Very high145 Ų14550.5 Ų50.568%0.67825%0.253SS*.Hα-helixtrans-56.4-43.1173.2-176.9176.1-170.700111.7P664 Y671 G672P664-E668 WeakPolarHBondContact O-CB 3.49Å; P664-E668 PolarHBondContact O-N 3.35Å; E668-Y671 PolarHBondContact O-N 2.86Å; E668-G672 PolarHBondContact O-N 3.48Å
669R89.4Confident90.7Very high27 Ų2747.7 Ų47.710%0.10224%0.24CC..Hα-helixtrans-62.4-43.9175.9-176.9175.6-175.9168.52.2112.5A392 L493 F549 A665 H666 L667 Y671 G672 M673A392-R669 PolarHBondContact O-NH1 3.26Å; A392-R669 PolarHBondContact O-NH2 3.28Å; L493-R669 VanDerWaalsContact CD2-NH2 3.27Å; F549-R669 HydrophobicContact CE1-CG 4.23Å; F549-R669 HydrophobicContact CZ-CG 4.09Å; A665-R669 WeakPolarHBondContact O-CB 3.39Å; A665-R669 PolarHBondContact O-N 3.07Å; H666-R669 PolarHBondContact O-N 2.72Å; L667-R669 VanDerWaalsContact C-N 3.29Å; L667-R669 PolarHBondContact O-N 2.74Å; R669-Y671 VanDerWaalsContact C-N 3.34Å; R669-G672 PolarHBondContact O-N 2.57Å; R669-M673 HydrophobicContact CG-CE 3.82Å; R669-M673 HydrophobicContact CG-SD 4.45Å; R669-M673 WeakPolarHBondContact O-CG 3.25Å; R669-M673 PolarHBondContact O-N 3.19Å
670L92Very high91Very high3 Ų345.9 Ų45.92%0.01623%0.232CC..Hα-helixtrans-64-41.7177.2-72165.7000111.1F549 I609 K612 L613 Q616 H666 L667 M673 I674F549-L670 HydrophobicContact CE1-CD2 3.6Å; F549-L670 HydrophobicContact CE1-CG 4.24Å; F549-L670 HydrophobicContact CZ-CD2 3.84Å; F549-L670 HydrophobicContact CZ-CG 4.1Å; I609-L670 HydrophobicContact CG2-CD2 4.11Å; K612-L670 HydrophobicContact CB-CD1 4.27Å; K612-L670 HydrophobicContact CB-CD2 4.27Å; L613-L670 HydrophobicContact CD2-CB 3.67Å; L613-L670 HydrophobicContact CD2-CD1 3.73Å; L613-L670 HydrophobicContact CD2-CG 4.28Å; L613-L670 HydrophobicContact CG-CB 4.18Å; L613-L670 HydrophobicContact CG-CD1 4.04Å; Q616-L670 HydrophobicContact CG-CD1 4.15Å; H666-L670 WeakPolarHBondContact O-CG 3.42Å; H666-L670 PolarHBondContact O-N 3.05Å; L667-L670 PolarHBondContact O-N 2.78Å; L667-L670 VanDerWaalsContact O-N 3.15Å; L670-M673 PolarHBondContact O-N 2.78Å; L670-I674 VanDerWaalsContact O-CG1 3.31Å; L670-I674 WeakPolarHBondContact O-CG1 3.24Å; L670-I674 PolarHBondContact O-N 2.81Å
671Y93.4Very high91.1Very high29 Ų2942.2 Ų42.211%0.11422%0.218CC..Hα-helixtrans-63.6-43.2176.9-76.414.8000111.7L613 L667 E668 R669 I674 T675 L697 L700 D701L613-Y671 HydrophobicContact CD2-CD1 4.08Å; L613-Y671 HydrophobicContact CD2-CE1 3.85Å; L667-Y671 HydrophobicContact CD2-CD1 3.97Å; L667-Y671 HydrophobicContact CD2-CD2 3.85Å; L667-Y671 HydrophobicContact CD2-CE1 3.58Å; L667-Y671 HydrophobicContact CD2-CE2 3.47Å; L667-Y671 VanDerWaalsContact CD2-CE2 3.47Å; L667-Y671 HydrophobicContact CD2-CG 4.1Å; L667-Y671 HydrophobicContact CG-CD1 4.45Å; L667-Y671 HydrophobicContact CG-CE1 4Å; L667-Y671 WeakPolarHBondContact O-CD1 3.26Å; L667-Y671 PolarHBondContact O-N 3.04Å; E668-Y671 PolarHBondContact O-N 2.86Å; R669-Y671 VanDerWaalsContact C-N 3.34Å; Y671-I674 PolarHBondContact O-N 2.91Å; Y671-T675 VanDerWaalsContact O-CB 3.32Å; Y671-T675 WeakPolarHBondContact O-CB 3.44Å; Y671-T675 PolarHBondContact O-N 2.9Å; Y671-T675 PolarHBondContact O-OG1 2.81Å; Y671-L697 HydrophobicContact CD2-CD2 4.36Å; Y671-L700 HydrophobicContact CD1-CB 4.25Å; Y671-L700 HydrophobicContact CD1-CD1 3.98Å; Y671-L700 HydrophobicContact CE1-CB 3.84Å; Y671-L700 HydrophobicContact CE1-CD1 4.42Å; Y671-L700 HydrophobicContact CE2-CB 4.17Å; Y671-L700 HydrophobicContact CG-CD1 4.05Å; Y671-L700 PolarHBondContact OH-O 2.95Å; Y671-L700 VanDerWaalsContact OH-O 3.12Å; Y671-D701 WeakPolarHBondContact CE2-OD1 3.48Å; Y671-D701 PolarHBondContact OH-OD1 2.95Å
672G91.8Very high91.4Very high31 Ų3134.9 Ų34.932%0.3219%0.186SC..Hα-helixtrans-56.8-50.4173.200000111.7E668 R669 I674 T675 D676E668-G672 PolarHBondContact O-N 3.48Å; R669-G672 PolarHBondContact O-N 2.57Å; G672-I674 PolarHBondContact O-N 3.05Å; G672-T675 WeakPolarHBondContact O-CB 3.16Å; G672-T675 PolarHBondContact O-N 2.69Å; G672-T675 VanDerWaalsContact O-N 3.14Å; G672-D676 PolarHBondContact O-N 3.18Å
673M93.2Very high91.7Very high31 Ų3133.1 Ų33.115%0.15318%0.178CC..Hα-helixtrans-62.9-39.2179.7-71.8-179.7-179.800113.6L493 F549 L550 R669 L670 T675 L677L493-M673 HydrophobicContact CD1-CE 3.99Å; F549-M673 HydrophobicContact CB-CE 4.48Å; F549-M673 HydrophobicContact CD1-CE 3.41Å; F549-M673 VanDerWaalsContact CD1-CE 3.41Å; F549-M673 HydrophobicContact CD1-SD 3.26Å; F549-M673 WeakPolarHBondContact CD1-SD 3.46Å; F549-M673 HydrophobicContact CE1-CE 3.79Å; F549-M673 HydrophobicContact CE1-SD 3.37Å; F549-M673 WeakPolarHBondContact CE1-SD 3.28Å; F549-M673 HydrophobicContact CG-CE 4.09Å; F549-M673 HydrophobicContact CG-SD 4.42Å; L550-M673 HydrophobicContact CD1-SD 4.02Å; L550-M673 HydrophobicContact CD2-SD 3.88Å; L550-M673 HydrophobicContact CG-SD 4.01Å; R669-M673 HydrophobicContact CG-CE 3.82Å; R669-M673 HydrophobicContact CG-SD 4.45Å; R669-M673 WeakPolarHBondContact O-CG 3.25Å; R669-M673 PolarHBondContact O-N 3.19Å; L670-M673 PolarHBondContact O-N 2.78Å; M673-T675 VanDerWaalsContact C-N 3.33Å; M673-L677 VanDerWaalsContact O-CB 3.23Å; M673-L677 WeakPolarHBondContact O-CB 3.34Å; M673-L677 PolarHBondContact O-N 3.08Å
674I94.9Very high91.9Very high0 Ų033.3 Ų33.30%018%0.179CC..Hα-helixtrans-68-38.4175.7-66.2168.9000110.7L606 I609 L613 L670 Y671 G672 L677 F678 L696 L700 F712L606-I674 HydrophobicContact CD2-CG2 4.49Å; I609-I674 HydrophobicContact CD1-CG1 4.03Å; I609-I674 HydrophobicContact CG2-CD1 3.83Å; I609-I674 HydrophobicContact CG2-CG1 4.09Å; L613-I674 HydrophobicContact CD1-CD1 3.35Å; L613-I674 HydrophobicContact CG-CD1 4.35Å; L670-I674 VanDerWaalsContact O-CG1 3.31Å; L670-I674 WeakPolarHBondContact O-CG1 3.24Å; L670-I674 PolarHBondContact O-N 2.81Å; Y671-I674 PolarHBondContact O-N 2.91Å; G672-I674 PolarHBondContact O-N 3.05Å; I674-L677 PolarHBondContact O-N 2.98Å; I674-F678 WeakPolarHBondContact O-CB 3.44Å; I674-F678 PolarHBondContact O-N 3.37Å; I674-L696 HydrophobicContact CG2-CD1 4.49Å; I674-L696 HydrophobicContact CG2-CD2 4.4Å; I674-L700 HydrophobicContact CB-CD1 4.37Å; I674-L700 HydrophobicContact CD1-CD1 4.47Å; I674-L700 HydrophobicContact CD1-CD2 3.71Å; I674-L700 HydrophobicContact CG2-CD1 4.2Å; I674-L700 HydrophobicContact CG2-CD2 4.26Å; I674-F712 HydrophobicContact CG2-CE2 3.92Å; I674-F712 HydrophobicContact CG2-CZ 3.82Å
675T94.6Very high92.1Very high18 Ų1834.8 Ų34.811%0.1118%0.178CC..Hα-helixtrans-64-45.6177.2-59.90000111Y671 G672 M673 F678 I679 V693Y671-T675 VanDerWaalsContact O-CB 3.32Å; Y671-T675 WeakPolarHBondContact O-CB 3.44Å; Y671-T675 PolarHBondContact O-N 2.9Å; Y671-T675 PolarHBondContact O-OG1 2.81Å; G672-T675 WeakPolarHBondContact O-CB 3.16Å; G672-T675 PolarHBondContact O-N 2.69Å; G672-T675 VanDerWaalsContact O-N 3.14Å; M673-T675 VanDerWaalsContact C-N 3.33Å; T675-F678 WeakPolarHBondContact O-CB 3.25Å; T675-F678 PolarHBondContact O-N 2.89Å; T675-I679 HydrophobicContact CG2-CD1 3.94Å; T675-I679 VanDerWaalsContact O-CG1 3.3Å; T675-I679 WeakPolarHBondContact O-CG1 3.26Å; T675-I679 PolarHBondContact O-N 3.37Å; T675-V693 HydrophobicContact CG2-CG1 3.69Å; T675-V693 HydrophobicContact CG2-CG2 4.05Å
676D93.6Very high92.3Very high73 Ų7336.4 Ų36.439%0.3920%0.198SC..Hα-helixtrans-64-43.9176.2-70.2-27.7000111.2G672 F678 I679 D680G672-D676 PolarHBondContact O-N 3.18Å; D676-F678 VanDerWaalsContact C-N 3.29Å; D676-F678 PolarHBondContact O-N 3.43Å; D676-I679 PolarHBondContact O-N 3.37Å; D676-D680 WeakPolarHBondContact O-CB 3.5Å; D676-D680 VanDerWaalsContact O-CG 3.29Å; D676-D680 PolarHBondContact O-N 3.06Å
677L94.9Very high92.6Very high3 Ų337.6 Ų37.62%0.01621%0.209CC..Hα-helixtrans-55.8-43.6174.5-173.872.9000112N569 I570 S571 V602 T605 L606 M673 I674 K681 F712N569-L677 WeakPolarHBondContact OD1-CD1 3.43Å; I570-L677 HydrophobicContact CG2-CD1 3.39Å; I570-L677 HydrophobicContact CG2-CG 4.41Å; S571-L677 WeakPolarHBondContact OG-CA 3.3Å; S571-L677 PolarHBondContact OG-N 2.8Å; V602-L677 HydrophobicContact CG1-CD2 4.47Å; T605-L677 HydrophobicContact CG2-CD1 4.25Å; T605-L677 HydrophobicContact CG2-CD2 4Å; L606-L677 HydrophobicContact CD2-CD2 4.01Å; L606-L677 HydrophobicContact CG-CD2 4.24Å; M673-L677 VanDerWaalsContact O-CB 3.23Å; M673-L677 WeakPolarHBondContact O-CB 3.34Å; M673-L677 PolarHBondContact O-N 3.08Å; I674-L677 PolarHBondContact O-N 2.98Å; L677-K681 WeakPolarHBondContact O-CB 3.25Å; L677-K681 PolarHBondContact O-N 3.42Å; L677-F712 HydrophobicContact CD2-CE1 4.21Å; L677-F712 HydrophobicContact CD2-CZ 4.47Å; L677-F712 HydrophobicContact CG-CE1 4.2Å
678F95.1Very high92.6Very high0 Ų042.1 Ų42.10%023%0.233CC..Hα-helixtrans-63.5-51.1176.4-179.6-103.8000111.2I674 T675 D676 D680 K681 F682 V689 K692 L696 F711 F712 A715I674-F678 WeakPolarHBondContact O-CB 3.44Å; I674-F678 PolarHBondContact O-N 3.37Å; T675-F678 WeakPolarHBondContact O-CB 3.25Å; T675-F678 PolarHBondContact O-N 2.89Å; D676-F678 VanDerWaalsContact C-N 3.29Å; D676-F678 PolarHBondContact O-N 3.43Å; F678-D680 VanDerWaalsContact C-N 3.31Å; F678-D680 PolarHBondContact O-N 3.45Å; F678-K681 PolarHBondContact O-N 3.02Å; F678-F682 HydrophobicContact CD2-CD2 4.09Å; F678-F682 AromaticContact CD2-CE2 3.76Å; F678-F682 HydrophobicContact CD2-CE2 3.76Å; F678-F682 HydrophobicContact CE1-CD2 4.4Å; F678-F682 AromaticContact CE2-CD2 3.89Å; F678-F682 HydrophobicContact CE2-CD2 3.89Å; F678-F682 AromaticContact CE2-CE2 3.33Å; F678-F682 HydrophobicContact CE2-CE2 3.33Å; F678-F682 HydrophobicContact CE2-CZ 4.32Å; F678-F682 HydrophobicContact CG-CD2 4.44Å; F678-F682 HydrophobicContact CZ-CD2 4.03Å; F678-F682 AromaticContact CZ-CE2 3.78Å; F678-F682 HydrophobicContact CZ-CE2 3.78Å; F678-F682 VanDerWaalsContact O-CD2 3.29Å; F678-F682 WeakPolarHBondContact O-CD2 3.4Å; F678-F682 PolarHBondContact O-N 3.03Å; F678-V689 HydrophobicContact CD1-CG2 3.75Å; F678-V689 HydrophobicContact CE1-CB 3.73Å; F678-V689 HydrophobicContact CE1-CG2 3.41Å; F678-V689 VanDerWaalsContact CE1-CG2 3.41Å; F678-V689 HydrophobicContact CZ-CB 4.2Å; F678-V689 HydrophobicContact CZ-CG2 4.13Å; F678-K692 HydrophobicContact CE1-CB 4.19Å; F678-K692 HydrophobicContact CZ-CB 4.3Å; F678-L696 HydrophobicContact CB-CD2 3.82Å; F678-L696 HydrophobicContact CD1-CD2 4.14Å; F678-L696 HydrophobicContact CG-CD2 3.93Å; F678-F711 HydrophobicContact CD2-CD1 4.45Å; F678-F711 HydrophobicContact CD2-CE1 4.26Å; F678-F711 HydrophobicContact CE1-CE1 4.35Å; F678-F711 AromaticContact CE2-CD1 3.82Å; F678-F711 HydrophobicContact CE2-CD1 3.82Å; F678-F711 AromaticContact CE2-CE1 3.49Å; F678-F711 HydrophobicContact CE2-CE1 3.49Å; F678-F711 VanDerWaalsContact CE2-CE1 3.49Å; F678-F711 HydrophobicContact CE2-CZ 4.48Å; F678-F711 HydrophobicContact CZ-CD1 4.34Å; F678-F711 AromaticContact CZ-CE1 3.56Å; F678-F711 HydrophobicContact CZ-CE1 3.56Å; F678-F711 HydrophobicContact CZ-CZ 4.2Å; F678-F712 HydrophobicContact CB-CE1 3.77Å; F678-F712 HydrophobicContact CB-CE2 4.31Å; F678-F712 HydrophobicContact CB-CZ 3.6Å; F678-F712 HydrophobicContact CD2-CD1 4.04Å; F678-F712 HydrophobicContact CD2-CD2 4.15Å; F678-F712 AromaticContact CD2-CE1 4Å; F678-F712 HydrophobicContact CD2-CE1 4Å; F678-F712 HydrophobicContact CD2-CE2 4.09Å; F678-F712 HydrophobicContact CD2-CG 4.15Å; F678-F712 HydrophobicContact CD2-CZ 4.03Å; F678-F712 HydrophobicContact CG-CE1 4.4Å; F678-F712 HydrophobicContact CG-CZ 4.3Å; F678-A715 HydrophobicContact CE2-CB 3.82Å; F678-A715 HydrophobicContact CZ-CB 3.79Å
679I94.3Very high92.8Very high36 Ų3635.6 Ų35.619%0.18520%0.203CC..Hα-helixtrans-60.1-43.9-179.9-67.8167.4000110.6T675 D676 F682 K683 V693T675-I679 HydrophobicContact CG2-CD1 3.94Å; T675-I679 VanDerWaalsContact O-CG1 3.3Å; T675-I679 WeakPolarHBondContact O-CG1 3.26Å; T675-I679 PolarHBondContact O-N 3.37Å; D676-I679 PolarHBondContact O-N 3.37Å; I679-F682 PolarHBondContact O-N 3.25Å; I679-K683 VanDerWaalsContact O-CB 3.27Å; I679-K683 WeakPolarHBondContact O-CB 3.4Å; I679-K683 PolarHBondContact O-N 3.27Å; I679-V693 HydrophobicContact CD1-CG2 4.16Å; I679-V693 HydrophobicContact CG1-CG2 4.34Å
680D94.2Very high92.8Very high18 Ų1840.8 Ų40.810%0.09623%0.226CC..Hα-helixtrans-67.2-41.7-177.8-74.6-35.9000112.7S571 S574 D676 F678 F682 K683 F684S571-D680 VanDerWaalsContact CA-OD2 3.29Å; S571-D680 WeakPolarHBondContact CA-OD2 3.48Å; S571-D680 VanDerWaalsContact CB-OD2 3.26Å; S571-D680 WeakPolarHBondContact CB-OD2 3.42Å; S571-D680 PolarHBondContact OG-OD2 2.93Å; S574-D680 WeakPolarHBondContact CB-OD1 3.2Å; S574-D680 VanDerWaalsContact OG-CG 3.28Å; S574-D680 PolarHBondContact OG-OD1 3.19Å; D676-D680 WeakPolarHBondContact O-CB 3.5Å; D676-D680 VanDerWaalsContact O-CG 3.29Å; D676-D680 PolarHBondContact O-N 3.06Å; F678-D680 VanDerWaalsContact C-N 3.31Å; F678-D680 PolarHBondContact O-N 3.45Å; D680-F682 VanDerWaalsContact C-N 3.29Å; D680-F682 PolarHBondContact O-N 3.49Å; D680-K683 WeakPolarHBondContact O-CB 3.45Å; D680-K683 PolarHBondContact O-N 3.43Å; D680-F684 VanDerWaalsContact O-CD2 3.24Å; D680-F684 WeakPolarHBondContact O-CD2 3.39Å; D680-F684 PolarHBondContact O-N 3.13Å
681K93.8Very high92.8Very high5 Ų546.4 Ų46.42%0.02226%0.261CS..Hα-helixtrans-51.8-50.3174-179.4-172.2-171.1179.40111.3V602 L677 F678 K685 F712 D713V602-K681 HydrophobicContact CG1-CD 4.17Å; V602-K681 HydrophobicContact CG2-CB 4.44Å; V602-K681 HydrophobicContact CG2-CD 4.01Å; V602-K681 HydrophobicContact CG2-CG 4.11Å; L677-K681 WeakPolarHBondContact O-CB 3.25Å; L677-K681 PolarHBondContact O-N 3.42Å; F678-K681 PolarHBondContact O-N 3.02Å; K681-K685 PolarHBondContact O-N 3.29Å; K681-F712 HydrophobicContact CD-CD1 4.11Å; K681-F712 PolarHBondContact NZ-O 3.08Å; K681-D713 IonicContact NZ-OD1 3.36Å; K681-D713 PolarHBondContact NZ-OD1 3.22Å
682F93.1Very high92.7Very high11 Ų1148.6 Ų48.65%0.04827%0.271CS..Hα-helixtrans-77-31.3-177.3-75.7-71000112.8F678 I679 D680 F684 K685 G686 T687 V689 A715F678-F682 HydrophobicContact CD2-CD2 4.09Å; F678-F682 AromaticContact CD2-CE2 3.76Å; F678-F682 HydrophobicContact CD2-CE2 3.76Å; F678-F682 HydrophobicContact CE1-CD2 4.4Å; F678-F682 AromaticContact CE2-CD2 3.89Å; F678-F682 HydrophobicContact CE2-CD2 3.89Å; F678-F682 AromaticContact CE2-CE2 3.33Å; F678-F682 HydrophobicContact CE2-CE2 3.33Å; F678-F682 HydrophobicContact CE2-CZ 4.32Å; F678-F682 HydrophobicContact CG-CD2 4.44Å; F678-F682 HydrophobicContact CZ-CD2 4.03Å; F678-F682 AromaticContact CZ-CE2 3.78Å; F678-F682 HydrophobicContact CZ-CE2 3.78Å; F678-F682 VanDerWaalsContact O-CD2 3.29Å; F678-F682 WeakPolarHBondContact O-CD2 3.4Å; F678-F682 PolarHBondContact O-N 3.03Å; I679-F682 PolarHBondContact O-N 3.25Å; D680-F682 VanDerWaalsContact C-N 3.29Å; D680-F682 PolarHBondContact O-N 3.49Å; F682-F684 VanDerWaalsContact C-N 3.29Å; F682-F684 PolarHBondContact O-N 3.44Å; F682-K685 CarbonylContact O-C 3.57Å; F682-K685 WeakPolarHBondContact O-CA 3.47Å; F682-K685 PolarHBondContact O-N 2.82Å; F682-G686 PolarHBondContact O-N 3.48Å; F682-G686 VanDerWaalsContact O-N 3.08Å; F682-T687 CarbonylContact C-O 3.56Å; F682-T687 VanDerWaalsContact C-O 3.25Å; F682-T687 WeakPolarHBondContact CB-OG1 3.12Å; F682-T687 WeakPolarHBondContact CD1-OG1 3.3Å; F682-T687 PolarHBondContact O-N 3.28Å; F682-T687 VanDerWaalsContact O-O 3.12Å; F682-T687 PolarHBondContact O-OG1 2.93Å; F682-V689 HydrophobicContact CB-CB 4.26Å; F682-V689 HydrophobicContact CB-CG1 3.64Å; F682-V689 HydrophobicContact CB-CG2 3.59Å; F682-V689 HydrophobicContact CD1-CG1 3.97Å; F682-V689 HydrophobicContact CD2-CB 4.35Å; F682-V689 HydrophobicContact CD2-CG1 3.92Å; F682-V689 HydrophobicContact CD2-CG2 3.77Å; F682-V689 HydrophobicContact CG-CB 4.34Å; F682-V689 HydrophobicContact CG-CG1 3.55Å; F682-V689 HydrophobicContact CG-CG2 3.91Å; F682-A715 WeakPolarHBondContact CE1-O 3.38Å; F682-A715 HydrophobicContact CE2-CB 4.07Å; F682-A715 HydrophobicContact CZ-CB 3.77Å; F682-A715 WeakPolarHBondContact CZ-O 3.46Å
683K92.7Very high92.7Very high72 Ų7248.4 Ų48.431%0.31326%0.264SS..Hα-helixtrans-57.5-41.1171.3-177.3-174.8174.2-164.50111.8S574 D578 I679 D680 K685 G686S574-K683 PolarHBondContact OG-NZ 3.31Å; D578-K683 IonicContact OD1-NZ 2.77Å; D578-K683 PolarHBondContact OD1-NZ 2.78Å; D578-K683 IonicContact OD2-NZ 3.29Å; D578-K683 PolarHBondContact OD2-NZ 2.86Å; I679-K683 VanDerWaalsContact O-CB 3.27Å; I679-K683 WeakPolarHBondContact O-CB 3.4Å; I679-K683 PolarHBondContact O-N 3.27Å; D680-K683 WeakPolarHBondContact O-CB 3.45Å; D680-K683 PolarHBondContact O-N 3.43Å; K683-K685 VanDerWaalsContact C-N 3.3Å; K683-K685 PolarHBondContact O-N 2.89Å; K683-G686 PolarHBondContact O-N 3.37Å; K683-G686 VanDerWaalsContact O-N 3.1Å
684F92.6Very high92.8Very high14 Ų1450.5 Ų50.56%0.06128%0.279CS..Hα-helixtrans-69.9-25.1174.5-79.3-69.5000113.6I570 I573 K577 Y595 I597 D680 F682 G686I570-F684 HydrophobicContact CD1-CD2 3.73Å; I570-F684 HydrophobicContact CD1-CE2 4.39Å; I570-F684 HydrophobicContact CD1-CG 4.47Å; I570-F684 HydrophobicContact CG1-CD2 3.57Å; I570-F684 HydrophobicContact CG1-CE2 3.72Å; I573-F684 HydrophobicContact CB-CZ 4.49Å; I573-F684 HydrophobicContact CG2-CE1 4.49Å; I573-F684 HydrophobicContact CG2-CE2 4.49Å; I573-F684 HydrophobicContact CG2-CZ 3.84Å; K577-F684 HydrophobicContact CD-CE1 3.87Å; K577-F684 HydrophobicContact CD-CZ 4.26Å; Y595-F684 HydrophobicContact CD1-CD1 4.19Å; Y595-F684 HydrophobicContact CD1-CE1 4.08Å; Y595-F684 AromaticContact CD2-CD1 3.59Å; Y595-F684 HydrophobicContact CD2-CD1 3.59Å; Y595-F684 HydrophobicContact CD2-CE1 4.05Å; Y595-F684 HydrophobicContact CE1-CD1 4.21Å; Y595-F684 HydrophobicContact CE1-CE1 4.42Å; Y595-F684 HydrophobicContact CE2-CB 4.39Å; Y595-F684 AromaticContact CE2-CD1 3.59Å; Y595-F684 HydrophobicContact CE2-CD1 3.59Å; Y595-F684 HydrophobicContact CE2-CE1 4.38Å; Y595-F684 HydrophobicContact CE2-CG 4.45Å; Y595-F684 AromaticContact CG-CD1 3.9Å; Y595-F684 HydrophobicContact CG-CD1 3.9Å; Y595-F684 AromaticContact CG-CE1 3.89Å; Y595-F684 HydrophobicContact CG-CE1 3.89Å; Y595-F684 AromaticContact CZ-CD1 3.92Å; I597-F684 HydrophobicContact CD1-CD1 4.32Å; I597-F684 HydrophobicContact CD1-CD2 4.28Å; I597-F684 HydrophobicContact CD1-CG 4.17Å; I597-F684 HydrophobicContact CG1-CB 4.2Å; I597-F684 HydrophobicContact CG1-CG 4.26Å; D680-F684 VanDerWaalsContact O-CD2 3.24Å; D680-F684 WeakPolarHBondContact O-CD2 3.39Å; D680-F684 PolarHBondContact O-N 3.13Å; F682-F684 VanDerWaalsContact C-N 3.29Å; F682-F684 PolarHBondContact O-N 3.44Å; F684-G686 PolarHBondContact O-N 2.82Å
685K90.6Very high92.7Very high104 Ų10454.8 Ų54.845%0.45230%0.302SS..THydrogen-bonded Turntrans-81.2-1169.9-62.9-173.2-178.8-167.80113.3E599 K681 F682 K683 T687E599-K685 WeakPolarHBondContact OE1-CE 3.33Å; E599-K685 IonicContact OE1-NZ 3.79Å; E599-K685 PolarHBondContact OE1-NZ 2.9Å; E599-K685 IonicContact OE2-NZ 2.94Å; E599-K685 PolarHBondContact OE2-NZ 3.27Å; K681-K685 PolarHBondContact O-N 3.29Å; F682-K685 CarbonylContact O-C 3.57Å; F682-K685 WeakPolarHBondContact O-CA 3.47Å; F682-K685 PolarHBondContact O-N 2.82Å; K683-K685 VanDerWaalsContact C-N 3.3Å; K683-K685 PolarHBondContact O-N 2.89Å; K685-T687 VanDerWaalsContact C-N 3.35Å
686G89.8Confident92.6Very high70 Ų7054 Ų5472%0.72230%0.297SS*.THydrogen-bonded Turntrans78.314.7-179.600000114.4F682 K683 F684F682-G686 PolarHBondContact O-N 3.48Å; F682-G686 VanDerWaalsContact O-N 3.08Å; K683-G686 PolarHBondContact O-N 3.37Å; K683-G686 VanDerWaalsContact O-N 3.1Å; F684-G686 PolarHBondContact O-N 2.82Å
687T91.5Very high92.5Very high69 Ų6953.6 Ų53.642%0.42330%0.295SS..  trans-110.2144.9-18056.60000111.5F682 K685F682-T687 CarbonylContact C-O 3.56Å; F682-T687 VanDerWaalsContact C-O 3.25Å; F682-T687 WeakPolarHBondContact CB-OG1 3.12Å; F682-T687 WeakPolarHBondContact CD1-OG1 3.3Å; F682-T687 PolarHBondContact O-N 3.28Å; F682-T687 VanDerWaalsContact O-O 3.12Å; F682-T687 PolarHBondContact O-OG1 2.93Å; K685-T687 VanDerWaalsContact C-N 3.35Å
688N90.6Very high92.4Very high125 Ų12560 Ų6067%0.66832%0.324SS*.  trans-104.1114.5175.1-175.8-15.4000109.4K690N688-K690 WeakPolarHBondContact OD1-CB 3.44Å; N688-K690 VanDerWaalsContact OD1-CG 3.32Å; N688-K690 WeakPolarHBondContact OD1-CG 3.23Å; N688-K690 PolarHBondContact OD1-N 3.42Å; N688-K690 VanDerWaalsContact OD1-N 3.15Å
689V91.9Very high92.2Very high8 Ų861.6 Ų61.65%0.04833%0.333CS..  trans-111.415.7-174.4-65.10000113.4F678 F682 T691 K692F678-V689 HydrophobicContact CD1-CG2 3.75Å; F678-V689 HydrophobicContact CE1-CB 3.73Å; F678-V689 HydrophobicContact CE1-CG2 3.41Å; F678-V689 VanDerWaalsContact CE1-CG2 3.41Å; F678-V689 HydrophobicContact CZ-CB 4.2Å; F678-V689 HydrophobicContact CZ-CG2 4.13Å; F682-V689 HydrophobicContact CB-CB 4.26Å; F682-V689 HydrophobicContact CB-CG1 3.64Å; F682-V689 HydrophobicContact CB-CG2 3.59Å; F682-V689 HydrophobicContact CD1-CG1 3.97Å; F682-V689 HydrophobicContact CD2-CB 4.35Å; F682-V689 HydrophobicContact CD2-CG1 3.92Å; F682-V689 HydrophobicContact CD2-CG2 3.77Å; F682-V689 HydrophobicContact CG-CB 4.34Å; F682-V689 HydrophobicContact CG-CG1 3.55Å; F682-V689 HydrophobicContact CG-CG2 3.91Å; V689-T691 PolarHBondContact O-N 3.11Å; V689-T691 VanDerWaalsContact O-N 3.07Å; V689-K692 WeakPolarHBondContact O-CB 3.49Å; V689-K692 PolarHBondContact O-N 2.89Å
690K89.9Confident92.1Very high136 Ų13659.9 Ų59.959%0.59132%0.324SS*.G310 helixtrans-56.2-29.1-178.7-73.2-176.2179.2-167.40113.6N688 K692 V693N688-K690 WeakPolarHBondContact OD1-CB 3.44Å; N688-K690 VanDerWaalsContact OD1-CG 3.32Å; N688-K690 WeakPolarHBondContact OD1-CG 3.23Å; N688-K690 PolarHBondContact OD1-N 3.42Å; N688-K690 VanDerWaalsContact OD1-N 3.15Å; K690-K692 PolarHBondContact O-N 3.36Å; K690-V693 WeakPolarHBondContact O-CB 3.33Å; K690-V693 WeakPolarHBondContact O-CG2 3.39Å; K690-V693 PolarHBondContact O-N 3.29Å
691T91.9Very high91.7Very high122 Ų12264.2 Ų64.275%0.74835%0.347SS*.G310 helixtrans-69.3-19176.953.40000113.7V689V689-T691 PolarHBondContact O-N 3.11Å; V689-T691 VanDerWaalsContact O-N 3.07Å
692K92.2Very high91.3Very high74 Ų7468.5 Ų68.532%0.32238%0.377SS..G310 helixtrans-92.1-4.7179.2-62.7-172176.8-172.90113.6F678 V689 K690 L695 L696 F711 A715F678-K692 HydrophobicContact CE1-CB 4.19Å; F678-K692 HydrophobicContact CZ-CB 4.3Å; V689-K692 WeakPolarHBondContact O-CB 3.49Å; V689-K692 PolarHBondContact O-N 2.89Å; K690-K692 PolarHBondContact O-N 3.36Å; K692-L695 PolarHBondContact O-N 2.84Å; K692-L696 PolarHBondContact O-N 3.48Å; K692-L696 VanDerWaalsContact O-N 3.16Å; K692-F711 HydrophobicContact CB-CZ 4.38Å; K692-A715 HydrophobicContact CD-CB 4.21Å; K692-A715 PolarHBondContact NZ-OXT 3.13Å
693V92.3Very high91Very high27 Ų2769.9 Ų69.916%0.16438%0.383CS..Hα-helixtrans-57.9-42.4179.7173.50000112.7T675 I679 K690 L695 L696 L697T675-V693 HydrophobicContact CG2-CG1 3.69Å; T675-V693 HydrophobicContact CG2-CG2 4.05Å; I679-V693 HydrophobicContact CD1-CG2 4.16Å; I679-V693 HydrophobicContact CG1-CG2 4.34Å; K690-V693 WeakPolarHBondContact O-CB 3.33Å; K690-V693 WeakPolarHBondContact O-CG2 3.39Å; K690-V693 PolarHBondContact O-N 3.29Å; V693-L695 VanDerWaalsContact C-N 3.29Å; V693-L695 PolarHBondContact O-N 3.08Å; V693-L696 WeakPolarHBondContact O-CB 3.18Å; V693-L696 PolarHBondContact O-N 3.45Å; V693-L696 VanDerWaalsContact O-N 3.1Å; V693-L697 HydrophobicContact CG1-CD1 4.4Å; V693-L697 HydrophobicContact CG1-CG 4.49Å; V693-L697 WeakPolarHBondContact O-CG 3.28Å; V693-L697 PolarHBondContact O-N 3.02Å
694P93.8Very high90.9Very high75 Ų7570.3 Ų70.349%0.48739%0.388SS..Hα-helixtrans-59.5-37.9176.6-25.435.9000113.4L696 L697 E698P694-L696 VanDerWaalsContact C-N 3.34Å; P694-L697 PolarHBondContact O-N 3.38Å; P694-E698 PolarHBondContact O-N 2.93Å
695L93.1Very high90.8Very high91 Ų9172.1 Ų72.148%0.47640%0.397SS..Hα-helixtrans-68.2-35.4176.9-69.190000111.8K692 V693 L697 E698 I699 F711K692-L695 PolarHBondContact O-N 2.84Å; V693-L695 VanDerWaalsContact C-N 3.29Å; V693-L695 PolarHBondContact O-N 3.08Å; L695-L697 VanDerWaalsContact C-N 3.33Å; L695-E698 PolarHBondContact O-N 2.64Å; L695-I699 WeakPolarHBondContact O-CG1 3.26Å; L695-I699 PolarHBondContact O-N 3.48Å; L695-F711 HydrophobicContact CB-CE2 4.25Å; L695-F711 HydrophobicContact CB-CZ 4.19Å
696L93.2Very high90.8Very high0 Ų072.5 Ų72.50%040%0.404CS..Hα-helixtrans-63-41.5174.1178.463.7000111.1I674 F678 K692 V693 P694 E698 I699 L700 L708 F711 F712I674-L696 HydrophobicContact CG2-CD1 4.49Å; I674-L696 HydrophobicContact CG2-CD2 4.4Å; F678-L696 HydrophobicContact CB-CD2 3.82Å; F678-L696 HydrophobicContact CD1-CD2 4.14Å; F678-L696 HydrophobicContact CG-CD2 3.93Å; K692-L696 PolarHBondContact O-N 3.48Å; K692-L696 VanDerWaalsContact O-N 3.16Å; V693-L696 WeakPolarHBondContact O-CB 3.18Å; V693-L696 PolarHBondContact O-N 3.45Å; V693-L696 VanDerWaalsContact O-N 3.1Å; P694-L696 VanDerWaalsContact C-N 3.34Å; L696-E698 PolarHBondContact O-N 3.31Å; L696-I699 PolarHBondContact O-N 2.97Å; L696-L700 HydrophobicContact CG-CD1 4.28Å; L696-L700 WeakPolarHBondContact O-CG 3.45Å; L696-L700 PolarHBondContact O-N 3.01Å; L696-L708 HydrophobicContact CD1-CD1 3.57Å; L696-F711 HydrophobicContact CB-CE1 3.89Å; L696-F711 HydrophobicContact CB-CZ 4.4Å; L696-F711 HydrophobicContact CD1-CD1 3.9Å; L696-F711 HydrophobicContact CD1-CE1 3.96Å; L696-F711 HydrophobicContact CG-CE1 4.47Å; L696-F712 HydrophobicContact CD1-CE2 3.99Å
697L91.9Very high91Very high66 Ų6671.2 Ų71.235%0.34639%0.387SS..Hα-helixtrans-62.6-41.1177.7-64.9174.5000111.7Y671 V693 P694 L695 I699 L700 D701Y671-L697 HydrophobicContact CD2-CD2 4.36Å; V693-L697 HydrophobicContact CG1-CD1 4.4Å; V693-L697 HydrophobicContact CG1-CG 4.49Å; V693-L697 WeakPolarHBondContact O-CG 3.28Å; V693-L697 PolarHBondContact O-N 3.02Å; P694-L697 PolarHBondContact O-N 3.38Å; L695-L697 VanDerWaalsContact C-N 3.33Å; L697-I699 VanDerWaalsContact C-N 3.3Å; L697-I699 PolarHBondContact O-N 3.01Å; L697-L700 HydrophobicContact CD2-CD1 4.46Å; L697-L700 PolarHBondContact O-N 3.47Å; L697-L700 VanDerWaalsContact O-N 3.1Å; L697-D701 PolarHBondContact O-N 3.29Å
698E91.7Very high91.1Very high137 Ų13768.3 Ų68.364%0.6437%0.368SS*.Hα-helixtrans-61-37.5174.1-69.5178.9179.900112.7P694 L695 L696 D701 S702P694-E698 PolarHBondContact O-N 2.93Å; L695-E698 PolarHBondContact O-N 2.64Å; L696-E698 PolarHBondContact O-N 3.31Å; E698-D701 PolarHBondContact O-N 3.29Å; E698-S702 PolarHBondContact O-N 3.41Å; E698-S702 VanDerWaalsContact O-N 3.16Å; E698-S702 PolarHBondContact O-OG 3.01Å
699I92.1Very high91.1Very high33 Ų3363.6 Ų63.617%0.16934%0.343CS..Hα-helixtrans-68.8-37174.9-66.1167.6000110.8L695 L696 L697 S702 Y703 L708 F711L695-I699 WeakPolarHBondContact O-CG1 3.26Å; L695-I699 PolarHBondContact O-N 3.48Å; L696-I699 PolarHBondContact O-N 2.97Å; L697-I699 VanDerWaalsContact C-N 3.3Å; L697-I699 PolarHBondContact O-N 3.01Å; I699-S702 PolarHBondContact O-OG 3.45Å; I699-Y703 VanDerWaalsContact O-CA 3.25Å; I699-Y703 WeakPolarHBondContact O-CA 3.49Å; I699-Y703 PolarHBondContact O-N 3.39Å; I699-L708 HydrophobicContact CG2-CB 4.26Å; I699-L708 HydrophobicContact CG2-CD1 4.15Å; I699-F711 HydrophobicContact CD1-CB 3.79Å; I699-F711 HydrophobicContact CD1-CD1 4.14Å; I699-F711 HydrophobicContact CD1-CD2 3.32Å; I699-F711 HydrophobicContact CD1-CE2 3.84Å; I699-F711 HydrophobicContact CD1-CG 3.48Å; I699-F711 VanDerWaalsContact CD1-CG 3.48Å; I699-F711 HydrophobicContact CD1-CZ 4.43Å
700L90.6Very high91.2Very high0 Ų066.6 Ų66.60%037%0.365CS..Hα-helixtrans-69.3-34.3176.5-70.9174.8000112.3L613 Y671 I674 L696 L697 Y703 L708L613-L700 HydrophobicContact CD1-CD2 4.31Å; Y671-L700 HydrophobicContact CD1-CB 4.25Å; Y671-L700 HydrophobicContact CD1-CD1 3.98Å; Y671-L700 HydrophobicContact CE1-CB 3.84Å; Y671-L700 HydrophobicContact CE1-CD1 4.42Å; Y671-L700 HydrophobicContact CE2-CB 4.17Å; Y671-L700 HydrophobicContact CG-CD1 4.05Å; Y671-L700 PolarHBondContact OH-O 2.95Å; Y671-L700 VanDerWaalsContact OH-O 3.12Å; I674-L700 HydrophobicContact CB-CD1 4.37Å; I674-L700 HydrophobicContact CD1-CD1 4.47Å; I674-L700 HydrophobicContact CD1-CD2 3.71Å; I674-L700 HydrophobicContact CG2-CD1 4.2Å; I674-L700 HydrophobicContact CG2-CD2 4.26Å; L696-L700 HydrophobicContact CG-CD1 4.28Å; L696-L700 WeakPolarHBondContact O-CG 3.45Å; L696-L700 PolarHBondContact O-N 3.01Å; L697-L700 HydrophobicContact CD2-CD1 4.46Å; L697-L700 PolarHBondContact O-N 3.47Å; L697-L700 VanDerWaalsContact O-N 3.1Å; L700-Y703 WeakPolarHBondContact O-CB 3.3Å; L700-Y703 PolarHBondContact O-N 3.14Å; L700-L708 HydrophobicContact CD2-CD1 4.04Å; L700-L708 HydrophobicContact CD2-CD2 4.06Å
701D86Confident91.4Very high110 Ų11061.8 Ų61.859%0.58834%0.344SS*.Hα-helixtrans-70.4-37.8176.9-71.7-21.2000112.9Y671 L697 E698Y671-D701 WeakPolarHBondContact CE2-OD1 3.48Å; Y671-D701 PolarHBondContact OH-OD1 2.95Å; L697-D701 PolarHBondContact O-N 3.29Å; E698-D701 PolarHBondContact O-N 3.29Å
702S84.9Confident91.4Very high94 Ų9456 Ų5666%0.65731%0.308SS*.Hα-helixtrans-80.8-21173.854.20000113.5E698 I699E698-S702 PolarHBondContact O-N 3.41Å; E698-S702 VanDerWaalsContact O-N 3.16Å; E698-S702 PolarHBondContact O-OG 3.01Å; I699-S702 PolarHBondContact O-OG 3.45Å
703Y88.3Confident91.2Very high40 Ų4056.4 Ų56.416%0.15731%0.314CS..THydrogen-bonded Turntrans32.793.5-178-165.5-113.8000116.1H610 L613 E614 L617 I699 L700 L708H610-Y703 VanDerWaalsContact CA-OH 3.3Å; H610-Y703 WeakPolarHBondContact CA-OH 3.48Å; H610-Y703 AromaticContact ND1-CE1 3.86Å; H610-Y703 AromaticContact ND1-CZ 3.58Å; H610-Y703 PolarHBondContact ND1-OH 3.13Å; H610-Y703 PolarHBondContact O-OH 3.41Å; L613-Y703 HydrophobicContact CB-CE1 4.44Å; L613-Y703 HydrophobicContact CB-CE2 4.16Å; L613-Y703 HydrophobicContact CD1-CD2 4.16Å; L613-Y703 HydrophobicContact CD1-CE2 3.5Å; L613-Y703 VanDerWaalsContact CD1-CE2 3.5Å; E614-Y703 HydrophobicContact CB-CE1 4.48Å; L617-Y703 VanDerWaalsContact CD1-CB 3.46Å; L617-Y703 HydrophobicContact CD1-CD1 3.47Å; L617-Y703 VanDerWaalsContact CD1-CD1 3.47Å; L617-Y703 HydrophobicContact CD1-CD2 4.38Å; L617-Y703 HydrophobicContact CD1-CE1 4.25Å; L617-Y703 HydrophobicContact CD1-CG 3.51Å; I699-Y703 VanDerWaalsContact O-CA 3.25Å; I699-Y703 WeakPolarHBondContact O-CA 3.49Å; I699-Y703 PolarHBondContact O-N 3.39Å; L700-Y703 WeakPolarHBondContact O-CB 3.3Å; L700-Y703 PolarHBondContact O-N 3.14Å; Y703-L708 HydrophobicContact CE2-CD2 4.33Å
704D90.1Very high90.7Very high81 Ų8159.3 Ų59.343%0.43334%0.341SS..  trans-122.4124.2160.3179.1-77.5000109.6N706 A707 L708D704-N706 VanDerWaalsContact C-N 3.34Å; D704-N706 PolarHBondContact O-N 3.48Å; D704-N706 WeakPolarHBondContact OD1-CA 3.11Å; D704-N706 WeakPolarHBondContact OD1-CB 3.48Å; D704-N706 PolarHBondContact OD1-N 2.94Å; D704-A707 HydrophobicContact CB-CB 3.85Å; D704-A707 PolarHBondContact O-N 3.04Å; D704-A707 PolarHBondContact OD1-N 3.32Å; D704-L708 WeakPolarHBondContact O-CB 3.5Å; D704-L708 PolarHBondContact O-N 3.44Å
705Q90.2Very high89.6Confident53 Ų5357.7 Ų57.725%0.24833%0.334CS..Hα-helixtrans-62.3-40-175-172.8-172.812.500112.5H610 L708 I709H610-Q705 PolarHBondContact CE1-OE1 3.11Å; Q705-L708 PolarHBondContact O-N 2.92Å; Q705-I709 HydrophobicContact CG-CD1 4.14Å; Q705-I709 WeakPolarHBondContact O-CG1 3.15Å; Q705-I709 PolarHBondContact O-N 3.34Å
706N91.6Very high89.4Confident111 Ų11156.1 Ų56.159%0.59433%0.327SS*.Hα-helixtrans-72.8-38.5-177.9-64.7-49.7000110.8D704 I709 S710D704-N706 VanDerWaalsContact C-N 3.34Å; D704-N706 PolarHBondContact O-N 3.48Å; D704-N706 WeakPolarHBondContact OD1-CA 3.11Å; D704-N706 WeakPolarHBondContact OD1-CB 3.48Å; D704-N706 PolarHBondContact OD1-N 2.94Å; N706-I709 PolarHBondContact O-N 3.07Å; N706-S710 VanDerWaalsContact O-CB 3.24Å; N706-S710 WeakPolarHBondContact O-CB 3.44Å; N706-S710 PolarHBondContact O-N 3.44Å; N706-S710 PolarHBondContact O-OG 3.43Å
707A92.8Very high89.2Confident44 Ų4459 Ų5936%0.36434%0.344SS..Hα-helixtrans-63.2-42.1173.100000111.2D704 S710 F711D704-A707 HydrophobicContact CB-CB 3.85Å; D704-A707 PolarHBondContact O-N 3.04Å; D704-A707 PolarHBondContact OD1-N 3.32Å; A707-S710 PolarHBondContact O-N 3.26Å; A707-F711 WeakPolarHBondContact O-CB 3.28Å; A707-F711 PolarHBondContact O-N 3.16Å
708L93.3Very high89.1Confident7 Ų758.6 Ų58.64%0.03734%0.344CS..Hα-helixtrans-61.6-49.8176-176.963.6000111.4L606 L696 I699 L700 Y703 D704 Q705 S710 F711 F712L606-L708 HydrophobicContact CD2-CD2 4.15Å; L696-L708 HydrophobicContact CD1-CD1 3.57Å; I699-L708 HydrophobicContact CG2-CB 4.26Å; I699-L708 HydrophobicContact CG2-CD1 4.15Å; L700-L708 HydrophobicContact CD2-CD1 4.04Å; L700-L708 HydrophobicContact CD2-CD2 4.06Å; Y703-L708 HydrophobicContact CE2-CD2 4.33Å; D704-L708 WeakPolarHBondContact O-CB 3.5Å; D704-L708 PolarHBondContact O-N 3.44Å; Q705-L708 PolarHBondContact O-N 2.92Å; L708-S710 VanDerWaalsContact C-N 3.33Å; L708-S710 PolarHBondContact O-N 2.97Å; L708-F711 WeakPolarHBondContact O-CB 3.45Å; L708-F711 PolarHBondContact O-N 3.41Å; L708-F712 HydrophobicContact CD1-CD2 4.07Å; L708-F712 HydrophobicContact CD1-CE2 3.81Å; L708-F712 HydrophobicContact CG-CD2 4.32Å; L708-F712 HydrophobicContact CG-CE2 4.27Å; L708-F712 WeakPolarHBondContact O-CD2 3.46Å; L708-F712 PolarHBondContact O-N 2.99Å
709I92.4Very high88.9Confident26 Ų2654 Ų5413%0.13333%0.326CS..Hα-helixtrans-61-45.1177.1-68.1168.7000110.5Q603 L606 Q705 N706 F711 F712 D713Q603-I709 HydrophobicContact CG-CG2 4.26Å; L606-I709 HydrophobicContact CD1-CG1 4.04Å; Q705-I709 HydrophobicContact CG-CD1 4.14Å; Q705-I709 WeakPolarHBondContact O-CG1 3.15Å; Q705-I709 PolarHBondContact O-N 3.34Å; N706-I709 PolarHBondContact O-N 3.07Å; I709-F711 VanDerWaalsContact C-N 3.28Å; I709-F711 PolarHBondContact O-N 2.83Å; I709-F712 WeakPolarHBondContact O-CB 3.34Å; I709-F712 PolarHBondContact O-N 2.91Å; I709-F712 VanDerWaalsContact O-N 3.14Å; I709-D713 PolarHBondContact O-N 3.06Å
710S92.7Very high88.7Confident72 Ų7255.3 Ų55.350%0.50334%0.336SS..Hα-helixtrans-60.7-38.9178.1-59.70000111.8N706 A707 L708 D713 A714N706-S710 VanDerWaalsContact O-CB 3.24Å; N706-S710 WeakPolarHBondContact O-CB 3.44Å; N706-S710 PolarHBondContact O-N 3.44Å; N706-S710 PolarHBondContact O-OG 3.43Å; A707-S710 PolarHBondContact O-N 3.26Å; L708-S710 VanDerWaalsContact C-N 3.33Å; L708-S710 PolarHBondContact O-N 2.97Å; S710-D713 PolarHBondContact O-N 3.37Å; S710-A714 WeakPolarHBondContact O-CB 3.26Å; S710-A714 PolarHBondContact O-N 2.9Å
711F93.5Very high88.6Confident34 Ų3459 Ų5915%0.14936%0.359CS..Hα-helixtrans-65.1-42.3175.4-176.4-96.1000111.8F678 K692 L695 L696 I699 A707 L708 I709 D713 A715F678-F711 HydrophobicContact CD2-CD1 4.45Å; F678-F711 HydrophobicContact CD2-CE1 4.26Å; F678-F711 HydrophobicContact CE1-CE1 4.35Å; F678-F711 AromaticContact CE2-CD1 3.82Å; F678-F711 HydrophobicContact CE2-CD1 3.82Å; F678-F711 AromaticContact CE2-CE1 3.49Å; F678-F711 HydrophobicContact CE2-CE1 3.49Å; F678-F711 VanDerWaalsContact CE2-CE1 3.49Å; F678-F711 HydrophobicContact CE2-CZ 4.48Å; F678-F711 HydrophobicContact CZ-CD1 4.34Å; F678-F711 AromaticContact CZ-CE1 3.56Å; F678-F711 HydrophobicContact CZ-CE1 3.56Å; F678-F711 HydrophobicContact CZ-CZ 4.2Å; K692-F711 HydrophobicContact CB-CZ 4.38Å; L695-F711 HydrophobicContact CB-CE2 4.25Å; L695-F711 HydrophobicContact CB-CZ 4.19Å; L696-F711 HydrophobicContact CB-CE1 3.89Å; L696-F711 HydrophobicContact CB-CZ 4.4Å; L696-F711 HydrophobicContact CD1-CD1 3.9Å; L696-F711 HydrophobicContact CD1-CE1 3.96Å; L696-F711 HydrophobicContact CG-CE1 4.47Å; I699-F711 HydrophobicContact CD1-CB 3.79Å; I699-F711 HydrophobicContact CD1-CD1 4.14Å; I699-F711 HydrophobicContact CD1-CD2 3.32Å; I699-F711 HydrophobicContact CD1-CE2 3.84Å; I699-F711 HydrophobicContact CD1-CG 3.48Å; I699-F711 VanDerWaalsContact CD1-CG 3.48Å; I699-F711 HydrophobicContact CD1-CZ 4.43Å; A707-F711 WeakPolarHBondContact O-CB 3.28Å; A707-F711 PolarHBondContact O-N 3.16Å; L708-F711 WeakPolarHBondContact O-CB 3.45Å; L708-F711 PolarHBondContact O-N 3.41Å; I709-F711 VanDerWaalsContact C-N 3.28Å; I709-F711 PolarHBondContact O-N 2.83Å; F711-D713 VanDerWaalsContact C-N 3.26Å; F711-D713 PolarHBondContact O-N 3.25Å; F711-A715 WeakPolarHBondContact O-CB 3.33Å; F711-A715 PolarHBondContact O-N 2.67Å; F711-A715 VanDerWaalsContact O-N 3.08Å
712F92.1Very high88.8Confident1 Ų155.4 Ų55.40%0.00434%0.342CS..Hα-helixtrans-61.4-34.5174.3-93.4-106.4000112.6V602 L606 I674 L677 F678 K681 L696 L708 I709V602-F712 HydrophobicContact CG1-CD1 3.56Å; V602-F712 HydrophobicContact CG1-CE1 3.99Å; V602-F712 HydrophobicContact CG1-CG 4.45Å; L606-F712 HydrophobicContact CD1-CB 4.41Å; L606-F712 HydrophobicContact CD1-CD1 4.23Å; L606-F712 HydrophobicContact CD1-CD2 4.06Å; L606-F712 HydrophobicContact CD1-CE1 4.49Å; L606-F712 HydrophobicContact CD1-CE2 4.34Å; L606-F712 HydrophobicContact CD1-CG 3.98Å; L606-F712 HydrophobicContact CD2-CE2 4.18Å; L606-F712 HydrophobicContact CD2-CZ 4.1Å; I674-F712 HydrophobicContact CG2-CE2 3.92Å; I674-F712 HydrophobicContact CG2-CZ 3.82Å; L677-F712 HydrophobicContact CD2-CE1 4.21Å; L677-F712 HydrophobicContact CD2-CZ 4.47Å; L677-F712 HydrophobicContact CG-CE1 4.2Å; F678-F712 HydrophobicContact CB-CE1 3.77Å; F678-F712 HydrophobicContact CB-CE2 4.31Å; F678-F712 HydrophobicContact CB-CZ 3.6Å; F678-F712 HydrophobicContact CD2-CD1 4.04Å; F678-F712 HydrophobicContact CD2-CD2 4.15Å; F678-F712 AromaticContact CD2-CE1 4Å; F678-F712 HydrophobicContact CD2-CE1 4Å; F678-F712 HydrophobicContact CD2-CE2 4.09Å; F678-F712 HydrophobicContact CD2-CG 4.15Å; F678-F712 HydrophobicContact CD2-CZ 4.03Å; F678-F712 HydrophobicContact CG-CE1 4.4Å; F678-F712 HydrophobicContact CG-CZ 4.3Å; K681-F712 HydrophobicContact CD-CD1 4.11Å; K681-F712 PolarHBondContact NZ-O 3.08Å; L696-F712 HydrophobicContact CD1-CE2 3.99Å; L708-F712 HydrophobicContact CD1-CD2 4.07Å; L708-F712 HydrophobicContact CD1-CE2 3.81Å; L708-F712 HydrophobicContact CG-CD2 4.32Å; L708-F712 HydrophobicContact CG-CE2 4.27Å; L708-F712 WeakPolarHBondContact O-CD2 3.46Å; L708-F712 PolarHBondContact O-N 2.99Å; I709-F712 WeakPolarHBondContact O-CB 3.34Å; I709-F712 PolarHBondContact O-N 2.91Å; I709-F712 VanDerWaalsContact O-N 3.14Å
713D88Confident89.1Confident82 Ų8252.4 Ų52.444%0.43932%0.318SS..Hα-helixtrans-87-27-176.7-69.8-18.3000113.4Q603 K681 I709 S710 F711Q603-D713 PolarHBondContact NE2-OD2 2.84Å; K681-D713 IonicContact NZ-OD1 3.36Å; K681-D713 PolarHBondContact NZ-OD1 3.22Å; I709-D713 PolarHBondContact O-N 3.06Å; S710-D713 PolarHBondContact O-N 3.37Å; F711-D713 VanDerWaalsContact C-N 3.26Å; F711-D713 PolarHBondContact O-N 3.25Å
714A83.2Confident89.1Confident89 Ų8953.4 Ų53.474%0.73633%0.331SS*.Hα-helixtrans-95.2-20.8-177.600000115.1S710S710-A714 WeakPolarHBondContact O-CB 3.26Å; S710-A714 PolarHBondContact O-N 2.9Å
715A69.7Low89Confident41 Ų4150.9 Ų50.934%0.33932%0.322SS..  trans-70.40-172.900000114.7F678 F682 K692 F711F678-A715 HydrophobicContact CE2-CB 3.82Å; F678-A715 HydrophobicContact CZ-CB 3.79Å; F682-A715 WeakPolarHBondContact CE1-O 3.38Å; F682-A715 HydrophobicContact CE2-CB 4.07Å; F682-A715 HydrophobicContact CZ-CB 3.77Å; F682-A715 WeakPolarHBondContact CZ-O 3.46Å; K692-A715 HydrophobicContact CD-CB 4.21Å; K692-A715 PolarHBondContact NZ-OXT 3.13Å; F711-A715 WeakPolarHBondContact O-CB 3.33Å; F711-A715 PolarHBondContact O-N 2.67Å; F711-A715 VanDerWaalsContact O-N 3.08Å

Retrieved 715 of 715 residues in 140.8 ms (Link to these results)