A0A2K5L9A2_CERAT Loading...

Orexin receptor type 2

Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding.

AlphaFold DB , UniProt , Accession A0A2K5L9A2, Species CERAT (Cercocebus atys, Sooty mangabey), Gene HCRTR2, Length 444 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	31.7	Very low	31.2	Very low	246 Å²	246	149 Å²	149	100%	1.212	85%	0.852	S	S	*	*				0	119.5	0	-102.2	163.6	142.6	0	0	107.9
2	S	29.7	Very low	31.1	Very low	130 Å²	130	147.3 Å²	147.3	91%	0.909	85%	0.853	S	S	*	*			trans	64.3	119.5	172.6	-136.2	0	0	0	0	116.9
3	G	26.6	Very low	31	Very low	58 Å²	58	153.5 Å²	153.5	60%	0.598	85%	0.854	S	S	*	*			cis	111	103.5	12.9	0	0	0	0	0	111.2
4	T	31.4	Very low	30.7	Very low	140 Å²	140	153.1 Å²	153.1	86%	0.859	85%	0.85	S	S	*	*			trans	162.8	101.2	150.3	28.8	0	0	0	0	109.4
5	K	30.7	Very low	30.5	Very low	202 Å²	202	159.1 Å²	159.1	88%	0.878	85%	0.854	S	S	*	*				74.4	104.3	89.8	-85.3	-170.1	176.1	-175.1	0	114.8
6	L	32.3	Very low	30.5	Very low	165 Å²	165	154.9 Å²	154.9	86%	0.864	84%	0.841	S	S	*	*	P	Polyproline II helix	trans	-67.8	136.2	156.2	-88.9	82.2	0	0	0	108.9
7	E	31.3	Very low	30.7	Very low	198 Å²	198	153.2 Å²	153.2	93%	0.925	84%	0.844	S	S	*	*	P	Polyproline II helix	trans	-96.8	117.9	166.6	-87.3	-178.9	128.9	0	0	110.2
8	D	31.7	Very low	30.7	Very low	152 Å²	152	149.4 Å²	149.4	81%	0.813	84%	0.836	S	S	*	*	P	Polyproline II helix	trans	-77.7	148.6	171.6	-78.6	-46.7	0	0	0	111.7
9	S	30	Very low	30.6	Very low	111 Å²	111	147 Å²	147	78%	0.776	83%	0.83	S	S	*	*	P	Polyproline II helix	trans	-65.3	146.2	172.2	-55.3	0	0	0	0	112.1
10	P	33.1	Very low	31.1	Very low	120 Å²	120	149.6 Å²	149.6	78%	0.779	84%	0.835	S	S	*	*	P	Polyproline II helix	trans	-77.6	139.3	177.6	30.1	-31.2	0	0	0	111.6
11	P	34.6	Very low	31.1	Very low	117 Å²	117	150.6 Å²	150.6	76%	0.76	84%	0.838	S	S	*	*	P	Polyproline II helix	trans	-80.6	148.6	-178.7	31.4	-32.8	0	0	0	112.5	R13	P11-R13 PolarHBondContact O-N 3.46Å
12	C	30.3	Very low	31.1	Very low	128 Å²	128	146.5 Å²	146.5	87%	0.865	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-54	122.2	169.8	-64.9	0	0	0	0	110.9	N14	C12-N14 PolarHBondContact O-N 3.33Å
13	R	29.1	Very low	31.7	Very low	228 Å²	228	149.5 Å²	149.5	86%	0.86	82%	0.82	S	S	*	*			trans	-75.7	113.4	171.8	-77.3	-174	-175.4	-171.4	1.9	110.2	P11 W15	P11-R13 PolarHBondContact O-N 3.46Å; R13-W15 PolarHBondContact O-N 3.25Å
14	N	27.5	Very low	32.1	Very low	149 Å²	149	153 Å²	153	80%	0.797	83%	0.83	S	S	*	*			trans	-62.1	119.2	158.5	-79.9	-16.4	0	0	0	109.2	C12 S16	C12-N14 PolarHBondContact O-N 3.33Å; N14-S16 PolarHBondContact O-N 3.39Å
15	W	27	Very low	32.4	Very low	242 Å²	242	155.7 Å²	155.7	92%	0.917	83%	0.833	S	S	*	*			trans	-87.4	86.8	166.8	-89	66.6	0	0	0	109.1	R13	R13-W15 PolarHBondContact O-N 3.25Å
16	S	30.8	Very low	32.7	Very low	92 Å²	92	153.7 Å²	153.7	64%	0.643	83%	0.827	S	S	*	*			trans	-121.7	124.6	160.5	50.8	0	0	0	0	108	N14	N14-S16 PolarHBondContact O-N 3.39Å
17	S	33.8	Very low	32.9	Very low	127 Å²	127	150.5 Å²	150.5	89%	0.888	82%	0.816	S	S	*	*			trans	71.6	107.6	170.1	56.9	0	0	0	0	119.3
18	A	30.3	Very low	33.2	Very low	85 Å²	85	150.8 Å²	150.8	70%	0.702	82%	0.815	S	S	*	*			trans	-153	98.2	147.2	0	0	0	0	0	105.8
19	S	29.5	Very low	33.5	Very low	103 Å²	103	150.9 Å²	150.9	72%	0.72	81%	0.814	S	S	*	*				83.3	115.6	95	65.4	0	0	0	0	112.6
20	E	39.7	Very low	33.8	Very low	198 Å²	198	152 Å²	152	93%	0.925	81%	0.812	S	S	*	*			trans	-20	123.2	168.1	-65	162.9	136.1	0	0	115.6
21	L	32.5	Very low	34.3	Very low	172 Å²	172	152.1 Å²	152.1	90%	0.901	81%	0.812	S	S	*	*			trans	-139.9	127.6	160.1	-104.5	140.6	0	0	0	108.5
22	N	30.4	Very low	35	Very low	159 Å²	159	152.5 Å²	152.5	85%	0.85	81%	0.812	S	S	*	*			trans	-44	140.6	-167.4	-86.3	-23.1	0	0	0	116.5	T24	N22-T24 PolarHBondContact O-N 3.43Å
23	E	42.1	Very low	35.8	Very low	194 Å²	194	153.7 Å²	153.7	91%	0.907	81%	0.81	S	S	*	*			trans	-48	110.7	161.8	-67.7	173.3	141.7	0	0	111.9
24	T	35.1	Very low	37.1	Very low	132 Å²	132	150.4 Å²	150.4	81%	0.81	80%	0.799	S	S	*	*			trans	-128.2	112.6	139.3	32.5	0	0	0	0	106.2	N22 E26	N22-T24 PolarHBondContact O-N 3.43Å; T24-E26 VanDerWaalsContact C-N 3.26Å; T24-E26 PolarHBondContact O-N 3.15Å
25	Q	38.7	Very low	38.9	Very low	195 Å²	195	148 Å²	148	91%	0.911	79%	0.786	S	S	*	*			trans	-74.9	76.6	-171.9	-162.6	167.8	12.3	0	0	109.7
26	E	37.3	Very low	40.9	Very low	161 Å²	161	140.8 Å²	140.8	75%	0.752	77%	0.766	S	S	*	*			trans	-71.8	129.8	152	-80.1	-83	150.5	0	0	106.4	T24 F28	T24-E26 VanDerWaalsContact C-N 3.26Å; T24-E26 PolarHBondContact O-N 3.15Å; E26-F28 PolarHBondContact O-N 3.02Å
27	P	36.3	Very low	42.7	Very low	98 Å²	98	141.4 Å²	141.4	64%	0.636	76%	0.758	S	S	*	*			trans	-61.2	111.1	-179.3	24.1	-29.7	0	0	0	108.5	L29	P27-L29 VanDerWaalsContact C-N 3.31Å; P27-L29 PolarHBondContact O-N 3.21Å
28	F	37	Very low	44.7	Very low	204 Å²	204	141.3 Å²	141.3	90%	0.895	74%	0.744	S	S	*	*			trans	-52.5	101.1	161.2	-98.2	-96.9	0	0	0	106.9	E26 N30	E26-F28 PolarHBondContact O-N 3.02Å; F28-N30 PolarHBondContact O-N 3.39Å
29	L	38.4	Very low	46.8	Very low	153 Å²	153	140.2 Å²	140.2	80%	0.801	72%	0.723	S	S	*	*			trans	-57	120.8	167.6	-96.9	93.1	0	0	0	107.3	P27 P31	P27-L29 VanDerWaalsContact C-N 3.31Å; P27-L29 PolarHBondContact O-N 3.21Å; L29-P31 WeakPolarHBondContact O-CD 3.47Å
30	N	35.4	Very low	48.8	Very low	135 Å²	135	138.4 Å²	138.4	72%	0.722	71%	0.705	S	S	*	*			trans	-54.6	126.8	169.9	-86.3	-25.9	0	0	0	109.3	F28 T32	F28-N30 PolarHBondContact O-N 3.39Å; N30-T32 PolarHBondContact O-N 3.25Å
31	P	45.5	Very low	50.5	Low	123 Å²	123	137 Å²	137	80%	0.799	69%	0.691	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.1	8.3	-178.4	-17.5	30.4	0	0	0	115.4	L29	L29-P31 WeakPolarHBondContact O-CD 3.47Å
32	T	48.4	Very low	52.7	Low	124 Å²	124	135.5 Å²	135.5	76%	0.761	68%	0.675	S	S	*	*	T	Hydrogen-bonded Turn	trans	-106.6	16	-165.7	50.3	0	0	0	0	114.9	N30	N30-T32 PolarHBondContact O-N 3.25Å
33	D	46.8	Very low	54.8	Low	153 Å²	153	128.7 Å²	128.7	82%	0.818	64%	0.638	S	S	*	*			trans	-141.8	49.5	178.2	-141.9	18.4	0	0	0	111.8	D35	D33-D35 PolarHBondContact O-N 3.33Å
34	Y	56.3	Low	56.3	Low	160 Å²	160	126.4 Å²	126.4	63%	0.627	62%	0.621	S	S	*	*			trans	-72	112.3	150.1	-98.5	-88.2	0	0	0	105.8	D36 F39	Y34-D36 PolarHBondContact O-N 3.49Å; Y34-F39 HydrophobicContact CD1-CB 4.06Å
35	D	66.4	Low	58.1	Low	99 Å²	99	129.6 Å²	129.6	53%	0.529	62%	0.619	S	S	.	*			trans	-49.8	115.5	162	-172.7	4.5	0	0	0	106.4	D33 E37 E38 F39	D33-D35 PolarHBondContact O-N 3.33Å; D35-E37 PolarHBondContact O-N 3.03Å; D35-E38 HydrophobicContact CB-CB 4.2Å; D35-E38 PolarHBondContact O-N 3.38Å; D35-F39 PolarHBondContact O-N 2.96Å
36	D	68.8	Low	59.7	Low	90 Å²	90	126.7 Å²	126.7	48%	0.481	61%	0.605	S	S	.	*	H	α-helix	trans	-55.3	-25.9	-174	-76.4	-52.4	0	0	0	109.6	Y34 L40 K203	Y34-D36 PolarHBondContact O-N 3.49Å; D36-L40 WeakPolarHBondContact O-CB 3.4Å; D36-L40 WeakPolarHBondContact O-CD1 3.49Å; D36-L40 WeakPolarHBondContact O-CG 3.39Å; D36-L40 PolarHBondContact O-N 3.07Å; D36-K203 IonicContact OD1-NZ 2.81Å; D36-K203 PolarHBondContact OD1-NZ 3.05Å
37	E	68.8	Low	61.2	Low	105 Å²	105	124.8 Å²	124.8	49%	0.491	59%	0.592	S	S	.	*	H	α-helix	trans	-66	-40.7	170.4	-79	-146.5	-179.9	0	0	114.8	D35 L40 R41	D35-E37 PolarHBondContact O-N 3.03Å; E37-L40 PolarHBondContact O-N 3.02Å; E37-R41 WeakPolarHBondContact O-CB 3.4Å; E37-R41 VanDerWaalsContact O-CG 3.29Å; E37-R41 WeakPolarHBondContact O-CG 3.31Å; E37-R41 PolarHBondContact O-N 3.32Å; E37-R41 IonicContact OE2-CZ 3.87Å; E37-R41 IonicContact OE2-NE 3.02Å; E37-R41 IonicContact OE2-NH2 3.64Å; E37-R41 PolarHBondContact OE2-NH2 3.34Å
38	E	74.3	Confident	63.1	Low	124 Å²	124	121 Å²	121	58%	0.579	57%	0.566	S	S	*	*	H	α-helix	trans	-70.8	-39.6	-179.5	-171.8	167.6	-165.1	0	0	111	D35 R41 Y42	D35-E38 HydrophobicContact CB-CB 4.2Å; D35-E38 PolarHBondContact O-N 3.38Å; E38-R41 PolarHBondContact O-N 3Å; E38-Y42 WeakPolarHBondContact O-CB 3.5Å; E38-Y42 PolarHBondContact O-N 3.19Å
39	F	74.4	Confident	64.9	Low	63 Å²	63	117 Å²	117	28%	0.276	55%	0.55	S	S	.	.	H	α-helix	trans	-62.8	-42	172.1	-179.3	-111.1	0	0	0	112	Y34 D35 Y42 L43 L200	Y34-F39 HydrophobicContact CD1-CB 4.06Å; D35-F39 PolarHBondContact O-N 2.96Å; F39-Y42 PolarHBondContact O-N 3.21Å; F39-L43 HydrophobicContact CD1-CD1 3.83Å; F39-L43 HydrophobicContact CE1-CD1 3.4Å; F39-L43 HydrophobicContact CE1-CG 4.35Å; F39-L43 HydrophobicContact CE2-CD1 4.35Å; F39-L43 HydrophobicContact CE2-CG 4.49Å; F39-L43 HydrophobicContact CG-CD1 4.48Å; F39-L43 HydrophobicContact CZ-CD1 3.69Å; F39-L43 HydrophobicContact CZ-CG 4.24Å; F39-L43 WeakPolarHBondContact O-CG 3.23Å; F39-L43 PolarHBondContact O-N 3.18Å; F39-L200 HydrophobicContact CE1-CD1 4.4Å; F39-L200 HydrophobicContact CZ-CD1 4.46Å
40	L	72.6	Confident	66.8	Low	65 Å²	65	110.7 Å²	110.7	34%	0.34	52%	0.519	S	S	.	.	H	α-helix	trans	-63.3	-45.8	173.8	-76.7	169	0	0	0	111.5	D36 E37 Y42 L43 W44 T204	D36-L40 WeakPolarHBondContact O-CB 3.4Å; D36-L40 WeakPolarHBondContact O-CD1 3.49Å; D36-L40 WeakPolarHBondContact O-CG 3.39Å; D36-L40 PolarHBondContact O-N 3.07Å; E37-L40 PolarHBondContact O-N 3.02Å; L40-Y42 VanDerWaalsContact C-N 3.32Å; L40-Y42 PolarHBondContact O-N 3.15Å; L40-L43 PolarHBondContact O-N 3.25Å; L40-W44 PolarHBondContact O-N 3.43Å; L40-T204 HydrophobicContact CD2-CG2 3.64Å
41	R	75.8	Confident	68.9	Low	168 Å²	168	108.8 Å²	108.8	63%	0.634	50%	0.504	S	S	*	.	H	α-helix	trans	-61.8	-39.8	177.4	-75.3	177.2	-162.1	174.9	9.5	112.1	E37 E38 W44 R45	E37-R41 WeakPolarHBondContact O-CB 3.4Å; E37-R41 VanDerWaalsContact O-CG 3.29Å; E37-R41 WeakPolarHBondContact O-CG 3.31Å; E37-R41 PolarHBondContact O-N 3.32Å; E37-R41 IonicContact OE2-CZ 3.87Å; E37-R41 IonicContact OE2-NE 3.02Å; E37-R41 IonicContact OE2-NH2 3.64Å; E37-R41 PolarHBondContact OE2-NH2 3.34Å; E38-R41 PolarHBondContact O-N 3Å; R41-W44 PolarHBondContact O-N 2.76Å; R41-R45 WeakPolarHBondContact O-CB 3.47Å; R41-R45 PolarHBondContact O-N 3.45Å
42	Y	77.6	Confident	70.7	Confident	141 Å²	141	111.4 Å²	111.4	55%	0.553	51%	0.505	S	S	*	.	H	α-helix	trans	-59.8	-50.9	173.6	175.1	-95.1	0	0	0	111.1	E38 F39 L40 W44 R45 E46	E38-Y42 WeakPolarHBondContact O-CB 3.5Å; E38-Y42 PolarHBondContact O-N 3.19Å; F39-Y42 PolarHBondContact O-N 3.21Å; L40-Y42 VanDerWaalsContact C-N 3.32Å; L40-Y42 PolarHBondContact O-N 3.15Å; Y42-W44 VanDerWaalsContact C-N 3.34Å; Y42-W44 PolarHBondContact O-N 2.96Å; Y42-R45 PolarHBondContact O-N 3.07Å; Y42-E46 HydrophobicContact CD2-CG 3.87Å; Y42-E46 HydrophobicContact CE2-CB 4.38Å; Y42-E46 HydrophobicContact CE2-CG 3.57Å; Y42-E46 HydrophobicContact CG-CG 4.49Å; Y42-E46 WeakPolarHBondContact O-CB 3.39Å; Y42-E46 PolarHBondContact O-N 2.82Å
43	L	75.5	Confident	72.4	Confident	16 Å²	16	110.7 Å²	110.7	8%	0.084	49%	0.49	C	S	.	.	H	α-helix	trans	-57.5	-44.5	176.9	-77.9	167.8	0	0	0	112.3	F39 L40 R45 Y47 L48 L206 F207	F39-L43 HydrophobicContact CD1-CD1 3.83Å; F39-L43 HydrophobicContact CE1-CD1 3.4Å; F39-L43 HydrophobicContact CE1-CG 4.35Å; F39-L43 HydrophobicContact CE2-CD1 4.35Å; F39-L43 HydrophobicContact CE2-CG 4.49Å; F39-L43 HydrophobicContact CG-CD1 4.48Å; F39-L43 HydrophobicContact CZ-CD1 3.69Å; F39-L43 HydrophobicContact CZ-CG 4.24Å; F39-L43 WeakPolarHBondContact O-CG 3.23Å; F39-L43 PolarHBondContact O-N 3.18Å; L40-L43 PolarHBondContact O-N 3.25Å; L43-R45 PolarHBondContact O-N 3.24Å; L43-Y47 WeakPolarHBondContact O-CA 3.5Å; L43-Y47 WeakPolarHBondContact O-CB 3.33Å; L43-Y47 PolarHBondContact O-N 3.47Å; L43-L48 PolarHBondContact O-N 3.09Å; L43-L206 HydrophobicContact CB-CD2 3.97Å; L43-L206 HydrophobicContact CD1-CD2 3.91Å; L43-L206 HydrophobicContact CD2-CD2 3.91Å; L43-L206 HydrophobicContact CG-CD2 4.17Å; L43-F207 HydrophobicContact CD2-CE2 4.38Å; L43-F207 HydrophobicContact CD2-CZ 4.19Å
44	W	73.6	Confident	74.3	Confident	145 Å²	145	104.4 Å²	104.4	55%	0.549	46%	0.455	S	S	.	.	H	α-helix	trans	-65.4	-37.7	178.6	-85.9	92.9	0	0	0	113	L40 R41 Y42 L48 H49	L40-W44 PolarHBondContact O-N 3.43Å; R41-W44 PolarHBondContact O-N 2.76Å; Y42-W44 VanDerWaalsContact C-N 3.34Å; Y42-W44 PolarHBondContact O-N 2.96Å; W44-L48 HydrophobicContact CD2-CD2 4.12Å; W44-L48 HydrophobicContact CE3-CB 4.03Å; W44-L48 HydrophobicContact CE3-CD2 3.42Å; W44-L48 VanDerWaalsContact CE3-CD2 3.42Å; W44-L48 HydrophobicContact CE3-CG 4.31Å; W44-L48 HydrophobicContact CH2-CD2 3.6Å; W44-L48 HydrophobicContact CZ2-CD2 4.27Å; W44-L48 HydrophobicContact CZ3-CD2 3.14Å; W44-L48 HydrophobicContact CZ3-CG 4.41Å; W44-L48 WeakPolarHBondContact O-CB 3.5Å; W44-L48 PolarHBondContact O-N 2.97Å; W44-H49 PolarHBondContact O-N 3.29Å
45	R	73.1	Confident	75.9	Confident	199 Å²	199	103.3 Å²	103.3	75%	0.751	45%	0.45	S	S	*	.	H	α-helix	trans	-82.2	-38.9	-175.6	-164.8	-179.6	-139.5	-179.9	5	113.4	R41 Y42 L43 H49	R41-R45 WeakPolarHBondContact O-CB 3.47Å; R41-R45 PolarHBondContact O-N 3.45Å; Y42-R45 PolarHBondContact O-N 3.07Å; L43-R45 PolarHBondContact O-N 3.24Å; R45-H49 WeakPolarHBondContact O-CB 3.31Å
46	E	72.2	Confident	77.1	Confident	134 Å²	134	103.7 Å²	103.7	63%	0.626	46%	0.456	S	S	*	.	H	α-helix	trans	-91.6	-31.6	-176.4	-69.2	-72.7	162.4	0	0	112.3	Y42	Y42-E46 HydrophobicContact CD2-CG 3.87Å; Y42-E46 HydrophobicContact CE2-CB 4.38Å; Y42-E46 HydrophobicContact CE2-CG 3.57Å; Y42-E46 HydrophobicContact CG-CG 4.49Å; Y42-E46 WeakPolarHBondContact O-CB 3.39Å; Y42-E46 PolarHBondContact O-N 2.82Å
47	Y	69.2	Low	78.2	Confident	121 Å²	121	100.6 Å²	100.6	48%	0.475	44%	0.439	S	S	.	.	T	Hydrogen-bonded Turn	trans	-105.1	-32.8	-174.2	-154.8	-90.4	0	0	0	113.9	L43 F207	L43-Y47 WeakPolarHBondContact O-CA 3.5Å; L43-Y47 WeakPolarHBondContact O-CB 3.33Å; L43-Y47 PolarHBondContact O-N 3.47Å; Y47-F207 AromaticContact CD1-CE1 3.84Å; Y47-F207 HydrophobicContact CD1-CE1 3.84Å; Y47-F207 HydrophobicContact CD1-CZ 4.29Å; Y47-F207 HydrophobicContact CE1-CD1 4.16Å; Y47-F207 AromaticContact CE1-CE1 3.39Å; Y47-F207 HydrophobicContact CE1-CE1 3.39Å; Y47-F207 HydrophobicContact CE1-CZ 4.25Å; Y47-F207 HydrophobicContact CE2-CE1 4.15Å; Y47-F207 HydrophobicContact CG-CE1 4.39Å; Y47-F207 AromaticContact CZ-CE1 3.55Å
48	L	75.3	Confident	79.4	Confident	19 Å²	19	97.3 Å²	97.3	10%	0.099	42%	0.424	C	S	.	.	S	Bend	trans	-100.8	-5.2	-177.8	-114.6	88.4	0	0	0	114.6	L43 W44 P50 T117 F121 L206	L43-L48 PolarHBondContact O-N 3.09Å; W44-L48 HydrophobicContact CD2-CD2 4.12Å; W44-L48 HydrophobicContact CE3-CB 4.03Å; W44-L48 HydrophobicContact CE3-CD2 3.42Å; W44-L48 VanDerWaalsContact CE3-CD2 3.42Å; W44-L48 HydrophobicContact CE3-CG 4.31Å; W44-L48 HydrophobicContact CH2-CD2 3.6Å; W44-L48 HydrophobicContact CZ2-CD2 4.27Å; W44-L48 HydrophobicContact CZ3-CD2 3.14Å; W44-L48 HydrophobicContact CZ3-CG 4.41Å; W44-L48 WeakPolarHBondContact O-CB 3.5Å; W44-L48 PolarHBondContact O-N 2.97Å; L48-P50 WeakPolarHBondContact O-CD 3.42Å; L48-T117 HydrophobicContact CD2-CG2 3.67Å; L48-T117 HydrophobicContact CG-CG2 3.98Å; L48-F121 HydrophobicContact CD2-CZ 4.39Å; L48-L206 HydrophobicContact CD1-CD1 3.53Å
49	H	74.6	Confident	80.4	Confident	119 Å²	119	93.7 Å²	93.7	55%	0.551	42%	0.415	S	S	*	.	S	Bend	trans	-72.8	125.1	179.3	-174.8	-77	0	0	0	110.4	W44 R45 K51	W44-H49 PolarHBondContact O-N 3.29Å; R45-H49 WeakPolarHBondContact O-CB 3.31Å; H49-K51 PolarHBondContact O-N 3.38Å
50	P	78.7	Confident	81.5	Confident	22 Å²	22	91.4 Å²	91.4	14%	0.143	41%	0.41	C	S	.	.	P	Polyproline II helix	trans	-65.5	138.6	-171.7	-20.5	30.4	0	0	0	113.8	L48 E54 W55 I58 I116	L48-P50 WeakPolarHBondContact O-CD 3.42Å; P50-E54 WeakPolarHBondContact CA-OE2 3.35Å; P50-E54 HydrophobicContact CB-CB 3.73Å; P50-E54 WeakPolarHBondContact CB-OE2 3.31Å; P50-W55 HydrophobicContact CB-CD2 4.48Å; P50-W55 HydrophobicContact CB-CZ2 4.33Å; P50-W55 HydrophobicContact CG-CH2 4.38Å; P50-W55 HydrophobicContact CG-CZ2 3.99Å; P50-W55 PolarHBondContact O-NE1 3.38Å; P50-I58 HydrophobicContact CB-CD1 4.38Å; P50-I58 HydrophobicContact CG-CD1 4.18Å; P50-I116 HydrophobicContact CG-CG2 4.45Å
51	K	79.7	Confident	82.6	Confident	94 Å²	94	88.3 Å²	88.3	41%	0.409	39%	0.394	S	S	.	.	P	Polyproline II helix	trans	-66.8	164.5	169.3	-65.3	177	178.6	175.2	0	110.7	H49 Y53 E54 W55 E340	H49-K51 PolarHBondContact O-N 3.38Å; K51-Y53 VanDerWaalsContact C-N 3.3Å; K51-Y53 HydrophobicContact CB-CD1 3.98Å; K51-Y53 HydrophobicContact CB-CE1 3.65Å; K51-Y53 HydrophobicContact CD-CE1 3.61Å; K51-Y53 HydrophobicContact CG-CE1 4.26Å; K51-Y53 PolarHBondContact O-N 3.32Å; K51-E54 HydrophobicContact CB-CG 4.18Å; K51-E54 WeakPolarHBondContact CB-OE1 3.32Å; K51-E54 WeakPolarHBondContact CG-OE1 3.35Å; K51-E54 VanDerWaalsContact N-CD 3.33Å; K51-E54 PolarHBondContact N-OE2 3.01Å; K51-E54 WeakPolarHBondContact O-CB 3.42Å; K51-E54 PolarHBondContact O-N 2.91Å; K51-W55 PolarHBondContact O-N 2.57Å; K51-E340 IonicContact NZ-OE1 2.81Å; K51-E340 PolarHBondContact NZ-OE1 3.05Å
52	E	83.8	Confident	83.7	Confident	178 Å²	178	84.9 Å²	84.9	83%	0.832	39%	0.387	S	S	*	.	H	α-helix	trans	-55.3	-41	-176.3	-65.7	-173.4	173.4	0	0	113.7	E54 W55	E52-E54 VanDerWaalsContact C-N 3.31Å; E52-E54 PolarHBondContact O-N 3.34Å; E52-W55 PolarHBondContact O-N 3Å
53	Y	82.6	Confident	84.6	Confident	110 Å²	110	83.3 Å²	83.3	43%	0.431	39%	0.387	S	S	.	.	H	α-helix	trans	-72.6	-23.9	178.7	64.9	-96.7	0	0	0	113.1	K51 W55 V56 L57	K51-Y53 VanDerWaalsContact C-N 3.3Å; K51-Y53 HydrophobicContact CB-CD1 3.98Å; K51-Y53 HydrophobicContact CB-CE1 3.65Å; K51-Y53 HydrophobicContact CD-CE1 3.61Å; K51-Y53 HydrophobicContact CG-CE1 4.26Å; K51-Y53 PolarHBondContact O-N 3.32Å; Y53-W55 VanDerWaalsContact C-N 3.33Å; Y53-V56 WeakPolarHBondContact O-CB 3.44Å; Y53-V56 PolarHBondContact O-N 3.33Å; Y53-L57 PolarHBondContact O-N 2.9Å
54	E	86.2	Confident	85.7	Confident	20 Å²	20	83 Å²	83	9%	0.093	39%	0.386	C	S	.	.	H	α-helix	trans	-71.4	-30.5	178.7	-67.7	173.2	-150.9	0	0	111.3	P50 K51 E52 V56 L57 I58 I116	P50-E54 WeakPolarHBondContact CA-OE2 3.35Å; P50-E54 HydrophobicContact CB-CB 3.73Å; P50-E54 WeakPolarHBondContact CB-OE2 3.31Å; K51-E54 HydrophobicContact CB-CG 4.18Å; K51-E54 WeakPolarHBondContact CB-OE1 3.32Å; K51-E54 WeakPolarHBondContact CG-OE1 3.35Å; K51-E54 VanDerWaalsContact N-CD 3.33Å; K51-E54 PolarHBondContact N-OE2 3.01Å; K51-E54 WeakPolarHBondContact O-CB 3.42Å; K51-E54 PolarHBondContact O-N 2.91Å; E52-E54 VanDerWaalsContact C-N 3.31Å; E52-E54 PolarHBondContact O-N 3.34Å; E54-V56 VanDerWaalsContact C-N 3.33Å; E54-V56 PolarHBondContact O-N 3.12Å; E54-L57 WeakPolarHBondContact O-CB 3.22Å; E54-L57 PolarHBondContact O-N 2.87Å; E54-I58 VanDerWaalsContact O-CG1 3.24Å; E54-I58 WeakPolarHBondContact O-CG1 3.36Å; E54-I58 PolarHBondContact O-N 3.27Å; E54-I116 HydrophobicContact CB-CD1 3.71Å; E54-I116 HydrophobicContact CG-CD1 4.1Å
55	W	90.6	Very high	86.9	Confident	138 Å²	138	79.1 Å²	79.1	52%	0.523	37%	0.373	S	S	.	.	H	α-helix	trans	-62.4	-40.5	170.4	-70.5	106.7	0	0	0	112.5	P50 K51 E52 Y53 L57 I58 A59	P50-W55 HydrophobicContact CB-CD2 4.48Å; P50-W55 HydrophobicContact CB-CZ2 4.33Å; P50-W55 HydrophobicContact CG-CH2 4.38Å; P50-W55 HydrophobicContact CG-CZ2 3.99Å; P50-W55 PolarHBondContact O-NE1 3.38Å; K51-W55 PolarHBondContact O-N 2.57Å; E52-W55 PolarHBondContact O-N 3Å; Y53-W55 VanDerWaalsContact C-N 3.33Å; W55-L57 VanDerWaalsContact C-N 3.31Å; W55-I58 HydrophobicContact CE3-CD1 4.16Å; W55-I58 HydrophobicContact CZ3-CD1 4.4Å; W55-I58 PolarHBondContact O-N 3.49Å; W55-A59 WeakPolarHBondContact O-CB 3.46Å; W55-A59 PolarHBondContact O-N 3.48Å
56	V	92.1	Very high	88.1	Confident	107 Å²	107	72.9 Å²	72.9	65%	0.648	36%	0.357	S	S	*	.	H	α-helix	trans	-64.1	-41	174.9	-179.4	0	0	0	0	110.3	Y53 E54 A59 G60	Y53-V56 WeakPolarHBondContact O-CB 3.44Å; Y53-V56 PolarHBondContact O-N 3.33Å; E54-V56 VanDerWaalsContact C-N 3.33Å; E54-V56 PolarHBondContact O-N 3.12Å; V56-A59 PolarHBondContact O-N 2.97Å; V56-G60 PolarHBondContact O-N 3.19Å
57	L	91.3	Very high	89.3	Confident	25 Å²	25	69.1 Å²	69.1	13%	0.131	34%	0.342	C	S	.	.	H	α-helix	trans	-63.5	-48	176.9	-176.6	70.2	0	0	0	112.1	Y53 E54 W55 A59 G60 Y61 I116 T347 W351	Y53-L57 PolarHBondContact O-N 2.9Å; E54-L57 WeakPolarHBondContact O-CB 3.22Å; E54-L57 PolarHBondContact O-N 2.87Å; W55-L57 VanDerWaalsContact C-N 3.31Å; L57-A59 VanDerWaalsContact C-N 3.33Å; L57-A59 PolarHBondContact O-N 3.45Å; L57-G60 CarbonylContact O-C 3.6Å; L57-G60 WeakPolarHBondContact O-CA 3.4Å; L57-G60 PolarHBondContact O-N 3.27Å; L57-G60 VanDerWaalsContact O-N 3.11Å; L57-Y61 HydrophobicContact CD1-CD2 3.87Å; L57-Y61 HydrophobicContact CD1-CE2 3.63Å; L57-Y61 HydrophobicContact CD2-CE2 4.3Å; L57-Y61 HydrophobicContact CG-CD2 3.81Å; L57-Y61 HydrophobicContact CG-CE2 3.81Å; L57-Y61 WeakPolarHBondContact O-CD2 3.2Å; L57-Y61 PolarHBondContact O-N 3.29Å; L57-I116 HydrophobicContact CD2-CD1 3.88Å; L57-T347 HydrophobicContact CD1-CG2 3.78Å; L57-T347 HydrophobicContact CD2-CG2 3.1Å; L57-T347 HydrophobicContact CG-CG2 4.04Å; L57-W351 HydrophobicContact CD1-CB 4.24Å
58	I	94.1	Very high	90.7	Very high	35 Å²	35	63.3 Å²	63.3	18%	0.179	32%	0.32	C	S	.	.	H	α-helix	trans	-56.1	-49.5	175.9	-69.8	162.3	0	0	0	109.8	P50 E54 W55 G60 Y61 I62 L112 I116	P50-I58 HydrophobicContact CB-CD1 4.38Å; P50-I58 HydrophobicContact CG-CD1 4.18Å; E54-I58 VanDerWaalsContact O-CG1 3.24Å; E54-I58 WeakPolarHBondContact O-CG1 3.36Å; E54-I58 PolarHBondContact O-N 3.27Å; W55-I58 HydrophobicContact CE3-CD1 4.16Å; W55-I58 HydrophobicContact CZ3-CD1 4.4Å; W55-I58 PolarHBondContact O-N 3.49Å; I58-G60 VanDerWaalsContact C-N 3.31Å; I58-G60 PolarHBondContact O-N 3Å; I58-Y61 PolarHBondContact O-N 3.38Å; I58-I62 HydrophobicContact CG2-CD1 3.79Å; I58-I62 VanDerWaalsContact O-CG1 3.31Å; I58-I62 WeakPolarHBondContact O-CG1 3.34Å; I58-I62 PolarHBondContact O-N 3.41Å; I58-L112 HydrophobicContact CG1-CD1 4.1Å; I58-I116 HydrophobicContact CD1-CD1 4Å; I58-I116 HydrophobicContact CD1-CG1 4.47Å; I58-I116 HydrophobicContact CG1-CD1 3.69Å; I58-I116 HydrophobicContact CG1-CG1 4.1Å
59	A	95.7	Very high	91.8	Very high	48 Å²	48	64.7 Å²	64.7	40%	0.397	33%	0.327	S	S	.	.	H	α-helix	trans	-58.9	-43.4	176.6	0	0	0	0	0	111.7	W55 V56 L57 I62 I63	W55-A59 WeakPolarHBondContact O-CB 3.46Å; W55-A59 PolarHBondContact O-N 3.48Å; V56-A59 PolarHBondContact O-N 2.97Å; L57-A59 VanDerWaalsContact C-N 3.33Å; L57-A59 PolarHBondContact O-N 3.45Å; A59-I62 PolarHBondContact O-N 3.45Å; A59-I63 VanDerWaalsContact O-CG1 3.28Å; A59-I63 WeakPolarHBondContact O-CG1 3.45Å; A59-I63 PolarHBondContact O-N 3.26Å
60	G	96.4	Very high	92.9	Very high	15 Å²	15	63.2 Å²	63.2	16%	0.155	32%	0.322	C	S	.	.	H	α-helix	trans	-60	-44.7	176	0	0	0	0	0	113.2	V56 L57 I58 I63 V64 W351	V56-G60 PolarHBondContact O-N 3.19Å; L57-G60 CarbonylContact O-C 3.6Å; L57-G60 WeakPolarHBondContact O-CA 3.4Å; L57-G60 PolarHBondContact O-N 3.27Å; L57-G60 VanDerWaalsContact O-N 3.11Å; I58-G60 VanDerWaalsContact C-N 3.31Å; I58-G60 PolarHBondContact O-N 3Å; G60-I63 PolarHBondContact O-N 3.22Å; G60-V64 WeakPolarHBondContact O-CG2 3.32Å; G60-V64 PolarHBondContact O-N 3.21Å; G60-W351 VanDerWaalsContact C-NE1 3.31Å; G60-W351 PolarHBondContact O-NE1 3Å
61	Y	97.1	Very high	93.8	Very high	1 Å²	1	62.6 Å²	62.6	0%	0.004	32%	0.32	C	S	.	.	H	α-helix	trans	-65.5	-41	176.3	-91.2	-79.2	0	0	0	112.3	L57 I58 V64 F65 L108 L112 D115 H350 W351 Y354	L57-Y61 HydrophobicContact CD1-CD2 3.87Å; L57-Y61 HydrophobicContact CD1-CE2 3.63Å; L57-Y61 HydrophobicContact CD2-CE2 4.3Å; L57-Y61 HydrophobicContact CG-CD2 3.81Å; L57-Y61 HydrophobicContact CG-CE2 3.81Å; L57-Y61 WeakPolarHBondContact O-CD2 3.2Å; L57-Y61 PolarHBondContact O-N 3.29Å; I58-Y61 PolarHBondContact O-N 3.38Å; Y61-V64 PolarHBondContact O-N 2.95Å; Y61-F65 VanDerWaalsContact O-CB 3.3Å; Y61-F65 WeakPolarHBondContact O-CB 3.4Å; Y61-F65 PolarHBondContact O-N 2.92Å; Y61-L108 HydrophobicContact CD1-CD1 4.48Å; Y61-L108 HydrophobicContact CD1-CD2 3.66Å; Y61-L108 HydrophobicContact CD1-CG 3.81Å; Y61-L108 HydrophobicContact CE1-CD2 4.44Å; Y61-L108 HydrophobicContact CE1-CG 4.23Å; Y61-L112 HydrophobicContact CD1-CB 4.23Å; Y61-L112 HydrophobicContact CD2-CB 4.43Å; Y61-L112 HydrophobicContact CD2-CD1 3.57Å; Y61-L112 HydrophobicContact CE2-CD1 4.16Å; Y61-L112 HydrophobicContact CG-CB 4.18Å; Y61-L112 HydrophobicContact CG-CD1 3.87Å; Y61-L112 HydrophobicContact CG-CG 4.41Å; Y61-D115 PolarHBondContact OH-OD2 3.47Å; Y61-H350 WeakPolarHBondContact OH-CB 3.47Å; Y61-W351 AromaticContact CD2-CD1 3.94Å; Y61-W351 HydrophobicContact CE2-CB 3.95Å; Y61-W351 HydrophobicContact CE2-CG 4.49Å; Y61-W351 PolarHBondContact OH-N 2.9Å; Y61-Y354 AromaticContact CE1-CD2 3.63Å; Y61-Y354 HydrophobicContact CE1-CD2 3.63Å; Y61-Y354 HydrophobicContact CE1-CE2 4.06Å
62	I	97.6	Very high	94.7	Very high	96 Å²	96	58.1 Å²	58.1	49%	0.492	30%	0.301	S	S	.	.	H	α-helix	trans	-62.3	-45.5	176.6	-68.7	167.5	0	0	0	110.7	I58 A59 V64 F65 V66	I58-I62 HydrophobicContact CG2-CD1 3.79Å; I58-I62 VanDerWaalsContact O-CG1 3.31Å; I58-I62 WeakPolarHBondContact O-CG1 3.34Å; I58-I62 PolarHBondContact O-N 3.41Å; A59-I62 PolarHBondContact O-N 3.45Å; I62-V64 PolarHBondContact O-N 3.27Å; I62-F65 PolarHBondContact O-N 2.99Å; I62-V66 WeakPolarHBondContact O-CG2 3.38Å; I62-V66 PolarHBondContact O-N 3.2Å
63	I	98.1	Very high	95.3	Very high	108 Å²	108	52.9 Å²	52.9	55%	0.554	28%	0.281	S	S	*	.	H	α-helix	trans	-59.5	-49	176.8	-69.1	165.2	0	0	0	110.2	A59 G60 F65 V66 V67	A59-I63 VanDerWaalsContact O-CG1 3.28Å; A59-I63 WeakPolarHBondContact O-CG1 3.45Å; A59-I63 PolarHBondContact O-N 3.26Å; G60-I63 PolarHBondContact O-N 3.22Å; I63-F65 PolarHBondContact O-N 3.34Å; I63-V66 PolarHBondContact O-N 2.68Å; I63-V67 HydrophobicContact CG2-CG2 4.32Å; I63-V67 WeakPolarHBondContact O-CB 3.49Å; I63-V67 VanDerWaalsContact O-CG2 3.24Å; I63-V67 WeakPolarHBondContact O-CG2 3.24Å; I63-V67 PolarHBondContact O-N 2.95Å
64	V	98.3	Very high	96	Very high	9 Å²	9	49 Å²	49	6%	0.055	27%	0.267	C	S	.	.	H	α-helix	trans	-60.3	-45.3	178.6	167.9	0	0	0	0	111	G60 Y61 I62 V66 V67 A68 L108 W351 Y354 A355 A358	G60-V64 WeakPolarHBondContact O-CG2 3.32Å; G60-V64 PolarHBondContact O-N 3.21Å; Y61-V64 PolarHBondContact O-N 2.95Å; I62-V64 PolarHBondContact O-N 3.27Å; V64-V66 PolarHBondContact O-N 2.9Å; V64-V67 PolarHBondContact O-N 3Å; V64-A68 WeakPolarHBondContact O-CB 3.38Å; V64-A68 PolarHBondContact O-N 3.47Å; V64-L108 HydrophobicContact CG1-CD1 4.05Å; V64-W351 HydrophobicContact CG2-CZ2 4.28Å; V64-Y354 VanDerWaalsContact CG1-C 3.45Å; V64-Y354 VanDerWaalsContact CG1-O 3.31Å; V64-Y354 WeakPolarHBondContact CG1-O 3.27Å; V64-A355 HydrophobicContact CG2-CB 4.11Å; V64-A358 HydrophobicContact CG1-CB 4.24Å
65	F	98.5	Very high	96.6	Very high	63 Å²	63	48.1 Å²	48.1	28%	0.276	26%	0.263	S	S	.	.	H	α-helix	trans	-57.5	-51.1	179	179.8	-89	0	0	0	111.8	Y61 I62 I63 L69 T104 L108 P109	Y61-F65 VanDerWaalsContact O-CB 3.3Å; Y61-F65 WeakPolarHBondContact O-CB 3.4Å; Y61-F65 PolarHBondContact O-N 2.92Å; I62-F65 PolarHBondContact O-N 2.99Å; I63-F65 PolarHBondContact O-N 3.34Å; F65-L69 HydrophobicContact CE1-CD2 4.01Å; F65-L69 HydrophobicContact CZ-CD2 4.19Å; F65-L69 WeakPolarHBondContact O-CB 3.49Å; F65-L69 PolarHBondContact O-N 3.38Å; F65-T104 HydrophobicContact CD2-CG2 3.74Å; F65-T104 VanDerWaalsContact CD2-O 3.3Å; F65-T104 WeakPolarHBondContact CD2-O 3.46Å; F65-T104 HydrophobicContact CE2-CG2 4.14Å; F65-T104 WeakPolarHBondContact CE2-O 3.37Å; F65-T104 HydrophobicContact CG-CG2 4.27Å; F65-L108 HydrophobicContact CB-CD1 4.03Å; F65-L108 HydrophobicContact CB-CD2 4.11Å; F65-L108 HydrophobicContact CD2-CD1 4.26Å; F65-L108 HydrophobicContact CD2-CD2 4.03Å; F65-P109 HydrophobicContact CE2-CG 4.13Å
66	V	98.3	Very high	96.9	Very high	69 Å²	69	41.8 Å²	41.8	42%	0.418	24%	0.24	S	C	.	.	H	α-helix	trans	-63.9	-47.3	-178.7	173.4	0	0	0	0	111	I62 I63 V64 I70	I62-V66 WeakPolarHBondContact O-CG2 3.38Å; I62-V66 PolarHBondContact O-N 3.2Å; I63-V66 PolarHBondContact O-N 2.68Å; V64-V66 PolarHBondContact O-N 2.9Å; V66-I70 HydrophobicContact CG1-CD1 3.67Å; V66-I70 HydrophobicContact CG1-CG1 4.5Å; V66-I70 WeakPolarHBondContact O-CB 3.28Å; V66-I70 WeakPolarHBondContact O-CG1 3.49Å; V66-I70 PolarHBondContact O-N 3.41Å
67	V	98.2	Very high	97.1	Very high	54 Å²	54	39.9 Å²	39.9	33%	0.327	23%	0.228	S	C	.	.	H	α-helix	trans	-67.3	-44.9	-177.8	174.9	0	0	0	0	111.3	I63 V64 G71 A358 I362	I63-V67 HydrophobicContact CG2-CG2 4.32Å; I63-V67 WeakPolarHBondContact O-CB 3.49Å; I63-V67 VanDerWaalsContact O-CG2 3.24Å; I63-V67 WeakPolarHBondContact O-CG2 3.24Å; I63-V67 PolarHBondContact O-N 2.95Å; V64-V67 PolarHBondContact O-N 3Å; V67-G71 WeakPolarHBondContact O-CA 3.49Å; V67-G71 PolarHBondContact O-N 3.47Å; V67-A358 HydrophobicContact CB-CB 4.12Å; V67-A358 HydrophobicContact CG1-CB 3.86Å; V67-I362 HydrophobicContact CG1-CD1 4.03Å; V67-I362 HydrophobicContact CG1-CG1 4.38Å
68	A	98.2	Very high	97.3	Very high	0 Å²	0	39 Å²	39	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-63.5	-45.6	178.3	0	0	0	0	0	111.3	V64 N72 T104 A358	V64-A68 WeakPolarHBondContact O-CB 3.38Å; V64-A68 PolarHBondContact O-N 3.47Å; A68-N72 VanDerWaalsContact O-CB 3.25Å; A68-N72 WeakPolarHBondContact O-CB 3.46Å; A68-N72 PolarHBondContact O-N 3.36Å; A68-N72 PolarHBondContact O-ND2 3.36Å; A68-T104 HydrophobicContact CB-CG2 3.98Å; A68-A358 HydrophobicContact CB-CB 4.03Å
69	L	98.3	Very high	97.4	Very high	47 Å²	47	37.3 Å²	37.3	25%	0.246	22%	0.216	C	C	.	.	H	α-helix	trans	-65.3	-55.3	-178.4	-175.3	62.2	0	0	0	111.4	F65 G71 V73 V101 T104 I105	F65-L69 HydrophobicContact CE1-CD2 4.01Å; F65-L69 HydrophobicContact CZ-CD2 4.19Å; F65-L69 WeakPolarHBondContact O-CB 3.49Å; F65-L69 PolarHBondContact O-N 3.38Å; L69-G71 PolarHBondContact O-N 3.2Å; L69-V73 HydrophobicContact CD1-CG2 4.42Å; L69-V73 WeakPolarHBondContact O-CB 3.33Å; L69-V73 WeakPolarHBondContact O-CG2 3.48Å; L69-V73 PolarHBondContact O-N 2.99Å; L69-V73 VanDerWaalsContact O-N 3.1Å; L69-V101 HydrophobicContact CD1-CG1 4.34Å; L69-T104 HydrophobicContact CB-CG2 4.19Å; L69-I105 HydrophobicContact CD1-CD1 3.9Å; L69-I105 HydrophobicContact CD1-CG1 3.9Å
70	I	97.4	Very high	97.3	Very high	88 Å²	88	41.5 Å²	41.5	45%	0.451	22%	0.222	S	C	.	.	H	α-helix	trans	-62.2	-48.2	-179	-64.9	173.9	0	0	0	110.2	V66 V73 L74	V66-I70 HydrophobicContact CG1-CD1 3.67Å; V66-I70 HydrophobicContact CG1-CG1 4.5Å; V66-I70 WeakPolarHBondContact O-CB 3.28Å; V66-I70 WeakPolarHBondContact O-CG1 3.49Å; V66-I70 PolarHBondContact O-N 3.41Å; I70-V73 PolarHBondContact O-N 2.98Å; I70-L74 HydrophobicContact CG2-CD1 3.89Å; I70-L74 HydrophobicContact CG2-CG 4.36Å; I70-L74 WeakPolarHBondContact O-CB 3.22Å; I70-L74 VanDerWaalsContact O-CG 3.26Å; I70-L74 WeakPolarHBondContact O-CG 3.35Å; I70-L74 PolarHBondContact O-N 3.49Å
71	G	97.5	Very high	97.2	Very high	10 Å²	10	48.3 Å²	48.3	10%	0.103	25%	0.247	C	C	.	.	H	α-helix	trans	-61.6	-48	-176.1	0	0	0	0	0	112.7	V67 L69 L74 V75	V67-G71 WeakPolarHBondContact O-CA 3.49Å; V67-G71 PolarHBondContact O-N 3.47Å; L69-G71 PolarHBondContact O-N 3.2Å; G71-L74 WeakPolarHBondContact O-CB 3.26Å; G71-L74 PolarHBondContact O-N 3.35Å; G71-V75 WeakPolarHBondContact O-CG2 3.37Å; G71-V75 PolarHBondContact O-N 2.91Å
72	N	98.1	Very high	97	Very high	0 Å²	0	49.7 Å²	49.7	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-72.1	-33.7	-178.2	-74.7	-65	0	0	0	112.4	A68 L74 V75 C76 S97 V101 S357 P361	A68-N72 VanDerWaalsContact O-CB 3.25Å; A68-N72 WeakPolarHBondContact O-CB 3.46Å; A68-N72 PolarHBondContact O-N 3.36Å; A68-N72 PolarHBondContact O-ND2 3.36Å; N72-L74 VanDerWaalsContact C-N 3.34Å; N72-V75 WeakPolarHBondContact O-CB 3.35Å; N72-V75 PolarHBondContact O-N 3.02Å; N72-C76 PolarHBondContact O-N 3.04Å; N72-C76 VanDerWaalsContact O-N 3.11Å; N72-C76 PolarHBondContact O-SG 3.1Å; N72-C76 VanDerWaalsContact O-SG 3.39Å; N72-S97 WeakPolarHBondContact OD1-CA 3.42Å; N72-S97 WeakPolarHBondContact OD1-CB 3.32Å; N72-S97 PolarHBondContact OD1-OG 3.27Å; N72-V101 HydrophobicContact CB-CG2 3.64Å; N72-S357 PolarHBondContact ND2-O 2.74Å; N72-P361 HydrophobicContact CB-CG 4.44Å
73	V	97.8	Very high	96.7	Very high	68 Å²	68	52.1 Å²	52.1	41%	0.412	26%	0.263	S	S	.	.	H	α-helix	trans	-61.9	-43.2	170.3	170.7	0	0	0	0	110.8	L69 I70 V75 C76 V77 V101	L69-V73 HydrophobicContact CD1-CG2 4.42Å; L69-V73 WeakPolarHBondContact O-CB 3.33Å; L69-V73 WeakPolarHBondContact O-CG2 3.48Å; L69-V73 PolarHBondContact O-N 2.99Å; L69-V73 VanDerWaalsContact O-N 3.1Å; I70-V73 PolarHBondContact O-N 2.98Å; V73-V75 VanDerWaalsContact C-N 3.33Å; V73-V75 PolarHBondContact O-N 3.41Å; V73-C76 WeakPolarHBondContact O-CB 3.33Å; V73-C76 PolarHBondContact O-N 3.45Å; V73-V77 HydrophobicContact CG1-CG2 4.31Å; V73-V77 WeakPolarHBondContact O-CG2 3.27Å; V73-V77 PolarHBondContact O-N 3.45Å; V73-V101 HydrophobicContact CG2-CG2 4.29Å
74	L	96.7	Very high	96.3	Very high	29 Å²	29	51.6 Å²	51.6	15%	0.152	26%	0.258	C	S	.	.	H	α-helix	trans	-62	-38.3	175.9	-73.6	173.9	0	0	0	112.5	I70 G71 N72 V77 A78 F375 A378 F379	I70-L74 HydrophobicContact CG2-CD1 3.89Å; I70-L74 HydrophobicContact CG2-CG 4.36Å; I70-L74 WeakPolarHBondContact O-CB 3.22Å; I70-L74 VanDerWaalsContact O-CG 3.26Å; I70-L74 WeakPolarHBondContact O-CG 3.35Å; I70-L74 PolarHBondContact O-N 3.49Å; G71-L74 WeakPolarHBondContact O-CB 3.26Å; G71-L74 PolarHBondContact O-N 3.35Å; N72-L74 VanDerWaalsContact C-N 3.34Å; L74-V77 PolarHBondContact O-N 3.49Å; L74-A78 WeakPolarHBondContact O-CB 3.27Å; L74-A78 PolarHBondContact O-N 3.19Å; L74-F375 HydrophobicContact CB-CD1 4.11Å; L74-F375 HydrophobicContact CB-CE1 3.82Å; L74-F375 HydrophobicContact CB-CZ 4.37Å; L74-A378 HydrophobicContact CD2-CB 3.78Å; L74-F379 HydrophobicContact CD1-CE1 4.28Å; L74-F379 HydrophobicContact CD1-CE2 3.85Å; L74-F379 HydrophobicContact CD1-CZ 3.5Å
75	V	97.5	Very high	96	Very high	0 Å²	0	51.2 Å²	51.2	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-58.3	-49.5	173.5	172.2	0	0	0	0	110.8	G71 N72 V73 A78 V79 I93 S97 P361 Y364 F371 F375	G71-V75 WeakPolarHBondContact O-CG2 3.37Å; G71-V75 PolarHBondContact O-N 2.91Å; N72-V75 WeakPolarHBondContact O-CB 3.35Å; N72-V75 PolarHBondContact O-N 3.02Å; V73-V75 VanDerWaalsContact C-N 3.33Å; V73-V75 PolarHBondContact O-N 3.41Å; V75-A78 PolarHBondContact O-N 3.4Å; V75-V79 WeakPolarHBondContact O-CG2 3.2Å; V75-V79 PolarHBondContact O-N 3.21Å; V75-I93 HydrophobicContact CG1-CG2 3.53Å; V75-S97 WeakPolarHBondContact CB-OG 3.35Å; V75-S97 VanDerWaalsContact CG1-OG 3.31Å; V75-S97 WeakPolarHBondContact CG1-OG 3.42Å; V75-P361 HydrophobicContact CG2-CB 4.25Å; V75-P361 HydrophobicContact CG2-CG 4.28Å; V75-Y364 HydrophobicContact CG1-CD2 4.46Å; V75-Y364 HydrophobicContact CG1-CE2 4.42Å; V75-Y364 HydrophobicContact CG2-CD2 3.72Å; V75-Y364 HydrophobicContact CG2-CE2 4.16Å; V75-F371 HydrophobicContact CG1-CE1 4.1Å; V75-F371 HydrophobicContact CG1-CZ 4.46Å; V75-F375 HydrophobicContact CG2-CE1 4.33Å; V75-F375 HydrophobicContact CG2-CZ 3.73Å
76	C	97.9	Very high	95.7	Very high	6 Å²	6	53.5 Å²	53.5	4%	0.041	26%	0.263	C	S	.	.	H	α-helix	trans	-59.1	-50.8	178	-67.5	0	0	0	0	111.6	N72 V73 A78 V79 W80	N72-C76 PolarHBondContact O-N 3.04Å; N72-C76 VanDerWaalsContact O-N 3.11Å; N72-C76 PolarHBondContact O-SG 3.1Å; N72-C76 VanDerWaalsContact O-SG 3.39Å; V73-C76 WeakPolarHBondContact O-CB 3.33Å; V73-C76 PolarHBondContact O-N 3.45Å; C76-A78 PolarHBondContact O-N 3.47Å; C76-V79 PolarHBondContact O-N 3.39Å; C76-W80 HydrophobicContact CB-CD2 4.38Å; C76-W80 HydrophobicContact CB-CE3 4.08Å; C76-W80 HydrophobicContact CB-CH2 3.89Å; C76-W80 HydrophobicContact CB-CZ2 4.18Å; C76-W80 HydrophobicContact CB-CZ3 3.83Å; C76-W80 WeakPolarHBondContact O-CB 3.5Å; C76-W80 VanDerWaalsContact O-CG 3.29Å; C76-W80 PolarHBondContact O-N 3.27Å
77	V	95.9	Very high	95.4	Very high	66 Å²	66	52.9 Å²	52.9	40%	0.4	26%	0.259	S	S	.	.	H	α-helix	trans	-60.1	-45.1	179.7	171.8	0	0	0	0	111.5	V73 L74 V79 W80 K81	V73-V77 HydrophobicContact CG1-CG2 4.31Å; V73-V77 WeakPolarHBondContact O-CG2 3.27Å; V73-V77 PolarHBondContact O-N 3.45Å; L74-V77 PolarHBondContact O-N 3.49Å; V77-V79 VanDerWaalsContact C-N 3.3Å; V77-V79 PolarHBondContact O-N 3.49Å; V77-W80 PolarHBondContact O-N 3.3Å; V77-K81 WeakPolarHBondContact O-CB 3.43Å; V77-K81 PolarHBondContact O-N 3.28Å
78	A	95.6	Very high	95.1	Very high	6 Å²	6	51.1 Å²	51.1	5%	0.05	25%	0.248	C	C	.	.	H	α-helix	trans	-59.1	-40.6	-179.5	0	0	0	0	0	112.2	L74 V75 C76 N82 F371 E374 F375	L74-A78 WeakPolarHBondContact O-CB 3.27Å; L74-A78 PolarHBondContact O-N 3.19Å; V75-A78 PolarHBondContact O-N 3.4Å; C76-A78 PolarHBondContact O-N 3.47Å; A78-N82 WeakPolarHBondContact O-CB 3.08Å; A78-N82 PolarHBondContact O-N 2.68Å; A78-N82 PolarHBondContact O-ND2 3.05Å; A78-F371 HydrophobicContact CB-CD1 4.34Å; A78-F371 HydrophobicContact CB-CE1 4.44Å; A78-E374 HydrophobicContact CB-CB 3.73Å; A78-E374 HydrophobicContact CB-CG 4.23Å; A78-F375 HydrophobicContact CB-CE1 4.36Å
79	V	95.9	Very high	94.8	Very high	0 Å²	0	51.3 Å²	51.3	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-78.6	-40	-179.9	178.4	0	0	0	0	112	V75 C76 V77 N90 V94 F371	V75-V79 WeakPolarHBondContact O-CG2 3.2Å; V75-V79 PolarHBondContact O-N 3.21Å; C76-V79 PolarHBondContact O-N 3.39Å; V77-V79 VanDerWaalsContact C-N 3.3Å; V77-V79 PolarHBondContact O-N 3.49Å; V79-N90 HydrophobicContact CG1-CB 4.12Å; V79-N90 HydrophobicContact CG2-CB 4.07Å; V79-V94 HydrophobicContact CB-CG2 3.57Å; V79-V94 HydrophobicContact CG1-CG2 3.73Å; V79-V94 HydrophobicContact CG2-CG2 3.78Å; V79-F371 HydrophobicContact CG2-CE1 3.78Å; V79-F371 HydrophobicContact CG2-CZ 3.87Å
80	W	95.1	Very high	94.6	Very high	137 Å²	137	50 Å²	50	52%	0.519	24%	0.243	S	C	.	.	H	α-helix	trans	-69.9	-43.3	-179.1	-67.6	-24.5	0	0	0	112.6	C76 V77 R86 V94 L98	C76-W80 HydrophobicContact CB-CD2 4.38Å; C76-W80 HydrophobicContact CB-CE3 4.08Å; C76-W80 HydrophobicContact CB-CH2 3.89Å; C76-W80 HydrophobicContact CB-CZ2 4.18Å; C76-W80 HydrophobicContact CB-CZ3 3.83Å; C76-W80 WeakPolarHBondContact O-CB 3.5Å; C76-W80 VanDerWaalsContact O-CG 3.29Å; C76-W80 PolarHBondContact O-N 3.27Å; V77-W80 PolarHBondContact O-N 3.3Å; W80-R86 PolarHBondContact O-NE 3.39Å; W80-R86 PolarHBondContact O-NH2 2.89Å; W80-V94 HydrophobicContact CZ2-CG1 3.95Å; W80-L98 HydrophobicContact CH2-CD2 4.25Å; W80-L98 HydrophobicContact CZ2-CD2 4.49Å
81	K	93.6	Very high	94.5	Very high	158 Å²	158	49 Å²	49	69%	0.687	23%	0.234	S	C	*	.	H	α-helix	trans	-69.2	-37.9	-178.5	-170.6	178.2	178	-176.7	0	112.3	V77	V77-K81 WeakPolarHBondContact O-CB 3.43Å; V77-K81 PolarHBondContact O-N 3.28Å
82	N	93.1	Very high	94.5	Very high	30 Å²	30	48.8 Å²	48.8	16%	0.16	23%	0.23	C	C	.	.			trans	-104.5	112	-168.7	-61.5	-68.1	0	0	0	112.8	A78 H84 M85 E374	A78-N82 WeakPolarHBondContact O-CB 3.08Å; A78-N82 PolarHBondContact O-N 2.68Å; A78-N82 PolarHBondContact O-ND2 3.05Å; N82-H84 VanDerWaalsContact C-N 3.26Å; N82-H84 PolarHBondContact O-N 2.89Å; N82-M85 HydrophobicContact CB-CB 4.21Å; N82-M85 HydrophobicContact CB-CG 3.97Å; N82-M85 WeakPolarHBondContact O-CB 3.38Å; N82-M85 PolarHBondContact O-N 3.47Å; N82-E374 VanDerWaalsContact CG-CD 3.49Å; N82-E374 VanDerWaalsContact CG-OE2 3.3Å; N82-E374 PolarHBondContact ND2-OE2 2.98Å
83	H	90.9	Very high	94.4	Very high	146 Å²	146	49 Å²	49	68%	0.676	23%	0.231	S	C	*	.	G	3₁₀ helix	trans	-57.3	-37.3	-179.5	-173.4	-93.1	0	0	0	113.1	M85 R86	H83-M85 PolarHBondContact O-N 3.44Å; H83-M85 VanDerWaalsContact O-N 3.15Å; H83-R86 WeakPolarHBondContact O-CB 3.32Å; H83-R86 PolarHBondContact O-N 3.41Å
84	H	89.6	Confident	94.4	Very high	97 Å²	97	46.1 Å²	46.1	45%	0.449	21%	0.214	S	C	.	.	G	3₁₀ helix	trans	-67.7	-13.2	179.8	76.4	-95.5	0	0	0	113.9	N82 E374	N82-H84 VanDerWaalsContact C-N 3.26Å; N82-H84 PolarHBondContact O-N 2.89Å; H84-E374 IonicContact CE1-OE1 3.24Å; H84-E374 PolarHBondContact CE1-OE1 2.88Å; H84-E374 IonicContact NE2-OE1 3.74Å
85	M	91.9	Very high	94.4	Very high	1 Å²	1	45 Å²	45	1%	0.005	21%	0.208	C	C	.	.	G	3₁₀ helix	trans	-92.4	-9.2	175.1	-69.7	-66.7	-88.3	0	0	113	N82 H83 T87 N90 K370 F371	N82-M85 HydrophobicContact CB-CB 4.21Å; N82-M85 HydrophobicContact CB-CG 3.97Å; N82-M85 WeakPolarHBondContact O-CB 3.38Å; N82-M85 PolarHBondContact O-N 3.47Å; H83-M85 PolarHBondContact O-N 3.44Å; H83-M85 VanDerWaalsContact O-N 3.15Å; M85-T87 PolarHBondContact O-N 3.28Å; M85-N90 WeakPolarHBondContact O-CB 3.21Å; M85-N90 PolarHBondContact O-ND2 3.06Å; M85-K370 HydrophobicContact CE-CB 3.94Å; M85-K370 HydrophobicContact SD-CB 3.46Å; M85-K370 WeakPolarHBondContact SD-CB 3.23Å; M85-K370 HydrophobicContact SD-CD 3.71Å; M85-K370 HydrophobicContact SD-CG 4.23Å; M85-F371 HydrophobicContact CE-CD1 3.61Å; M85-F371 HydrophobicContact CE-CD2 4Å; M85-F371 HydrophobicContact CE-CE1 3.63Å; M85-F371 HydrophobicContact CE-CE2 4Å; M85-F371 HydrophobicContact CE-CG 3.79Å; M85-F371 HydrophobicContact CE-CZ 3.82Å
86	R	93.2	Very high	94.4	Very high	112 Å²	112	45 Å²	45	42%	0.423	21%	0.208	S	C	.	.			trans	-78.8	67.4	-175.1	-62.6	-179.2	-171.1	167	1.7	112.5	W80 H83	W80-R86 PolarHBondContact O-NE 3.39Å; W80-R86 PolarHBondContact O-NH2 2.89Å; H83-R86 WeakPolarHBondContact O-CB 3.32Å; H83-R86 PolarHBondContact O-N 3.41Å
87	T	91.7	Very high	94.4	Very high	56 Å²	56	44.8 Å²	44.8	34%	0.344	21%	0.206	S	C	.	.			trans	-105	159.2	176.4	68.4	0	0	0	0	111.4	M85 T89 N90 Y91	M85-T87 PolarHBondContact O-N 3.28Å; T87-T89 PolarHBondContact O-N 3.25Å; T87-N90 PolarHBondContact O-N 3.47Å; T87-N90 WeakPolarHBondContact OG1-CB 3.46Å; T87-N90 VanDerWaalsContact OG1-CG 3.27Å; T87-N90 PolarHBondContact OG1-N 2.88Å; T87-N90 PolarHBondContact OG1-ND2 3.43Å; T87-Y91 WeakPolarHBondContact O-CD2 3.47Å; T87-Y91 PolarHBondContact O-N 3.01Å
88	V	92.3	Very high	94.5	Very high	16 Å²	16	45.1 Å²	45.1	10%	0.097	21%	0.205	C	C	.	.	H	α-helix	trans	-55.5	-47	-178.9	168.3	0	0	0	0	112.8	N90 Y91 F92 S164 A169	V88-N90 VanDerWaalsContact C-N 3.3Å; V88-N90 PolarHBondContact O-N 2.99Å; V88-Y91 PolarHBondContact O-N 3Å; V88-F92 HydrophobicContact CG1-CD2 4.17Å; V88-F92 HydrophobicContact CG1-CE2 3.78Å; V88-F92 WeakPolarHBondContact O-CD2 3.31Å; V88-F92 PolarHBondContact O-N 2.83Å; V88-S164 VanDerWaalsContact CB-OG 3.31Å; V88-S164 WeakPolarHBondContact CB-OG 3.48Å; V88-S164 VanDerWaalsContact CG1-OG 3.23Å; V88-S164 WeakPolarHBondContact CG1-OG 3.36Å; V88-S164 WeakPolarHBondContact CG2-OG 3.49Å; V88-A169 HydrophobicContact CB-CB 4.3Å; V88-A169 HydrophobicContact CG1-CB 3.65Å; V88-A169 HydrophobicContact CG2-CB 4.15Å
89	T	90.9	Very high	94.6	Very high	5 Å²	5	44.8 Å²	44.8	3%	0.031	20%	0.203	C	C	.	.	H	α-helix	trans	-63.9	-35.6	176	-63.3	0	0	0	0	112.6	T87 Y91 F92 I93 I148 D151 R152 L306	T87-T89 PolarHBondContact O-N 3.25Å; T89-Y91 VanDerWaalsContact C-N 3.32Å; T89-Y91 PolarHBondContact O-N 3.05Å; T89-F92 PolarHBondContact O-N 3.32Å; T89-I93 HydrophobicContact CG2-CD1 4.03Å; T89-I93 HydrophobicContact CG2-CG1 4.41Å; T89-I93 WeakPolarHBondContact O-CG1 3.49Å; T89-I93 PolarHBondContact O-N 3.37Å; T89-I148 HydrophobicContact CG2-CG2 4.18Å; T89-D151 PolarHBondContact OG1-OD2 3.4Å; T89-R152 VanDerWaalsContact OG1-CZ 3.24Å; T89-R152 PolarHBondContact OG1-NE 2.93Å; T89-R152 PolarHBondContact OG1-NH2 3.35Å; T89-L306 HydrophobicContact CG2-CD2 4.48Å
90	N	94	Very high	94.7	Very high	18 Å²	18	44.9 Å²	44.9	10%	0.096	20%	0.203	C	C	.	.	H	α-helix	trans	-70.3	-28.9	177.5	-71.4	-1.5	0	0	0	112.2	V79 M85 T87 V88 I93 V94	V79-N90 HydrophobicContact CG1-CB 4.12Å; V79-N90 HydrophobicContact CG2-CB 4.07Å; M85-N90 WeakPolarHBondContact O-CB 3.21Å; M85-N90 PolarHBondContact O-ND2 3.06Å; T87-N90 PolarHBondContact O-N 3.47Å; T87-N90 WeakPolarHBondContact OG1-CB 3.46Å; T87-N90 VanDerWaalsContact OG1-CG 3.27Å; T87-N90 PolarHBondContact OG1-N 2.88Å; T87-N90 PolarHBondContact OG1-ND2 3.43Å; V88-N90 VanDerWaalsContact C-N 3.3Å; V88-N90 PolarHBondContact O-N 2.99Å; N90-I93 PolarHBondContact O-N 3.48Å; N90-V94 VanDerWaalsContact O-CG2 3.32Å; N90-V94 WeakPolarHBondContact O-CG2 3.37Å; N90-V94 PolarHBondContact O-N 3.2Å
91	Y	96.2	Very high	94.8	Very high	68 Å²	68	39.5 Å²	39.5	27%	0.267	19%	0.186	S	C	.	.	H	α-helix	trans	-64.3	-39.8	169.5	-70.4	-54	0	0	0	112.3	T87 V88 T89 V94 N95 A166	T87-Y91 WeakPolarHBondContact O-CD2 3.47Å; T87-Y91 PolarHBondContact O-N 3.01Å; V88-Y91 PolarHBondContact O-N 3Å; T89-Y91 VanDerWaalsContact C-N 3.32Å; T89-Y91 PolarHBondContact O-N 3.05Å; Y91-V94 PolarHBondContact O-N 2.89Å; Y91-N95 PolarHBondContact O-N 3.23Å; Y91-A166 HydrophobicContact CD2-CB 4.45Å; Y91-A166 HydrophobicContact CE2-CB 3.79Å
92	F	96.8	Very high	95	Very high	6 Å²	6	34.2 Å²	34.2	3%	0.026	17%	0.165	C	C	.	.	H	α-helix	trans	-67.9	-38.4	173.1	-71	-59.4	0	0	0	112.4	V88 T89 V94 N95 L96 T144 C147 I148 A169 I173 I176	V88-F92 HydrophobicContact CG1-CD2 4.17Å; V88-F92 HydrophobicContact CG1-CE2 3.78Å; V88-F92 WeakPolarHBondContact O-CD2 3.31Å; V88-F92 PolarHBondContact O-N 2.83Å; T89-F92 PolarHBondContact O-N 3.32Å; F92-V94 VanDerWaalsContact C-N 3.32Å; F92-V94 PolarHBondContact O-N 3.32Å; F92-N95 WeakPolarHBondContact O-CB 3.45Å; F92-N95 PolarHBondContact O-N 3.45Å; F92-N95 VanDerWaalsContact O-N 3.15Å; F92-L96 PolarHBondContact O-N 2.74Å; F92-T144 HydrophobicContact CB-CG2 3.86Å; F92-T144 HydrophobicContact CD1-CG2 4.2Å; F92-T144 HydrophobicContact CG-CG2 4.46Å; F92-T144 WeakPolarHBondContact O-CG2 3.39Å; F92-C147 HydrophobicContact CD1-CB 4.29Å; F92-C147 HydrophobicContact CE1-CB 3.8Å; F92-C147 HydrophobicContact CE2-CB 4.31Å; F92-C147 HydrophobicContact CZ-CB 3.81Å; F92-I148 HydrophobicContact CB-CD1 3.73Å; F92-I148 HydrophobicContact CB-CG1 3.45Å; F92-I148 VanDerWaalsContact CB-CG1 3.45Å; F92-I148 HydrophobicContact CD2-CG1 4.13Å; F92-I148 HydrophobicContact CG-CG1 3.99Å; F92-A169 HydrophobicContact CE2-CB 4.34Å; F92-A169 HydrophobicContact CZ-CB 4.33Å; F92-I173 HydrophobicContact CD1-CD1 4.35Å; F92-I173 HydrophobicContact CD1-CG1 3.92Å; F92-I173 HydrophobicContact CE1-CG1 3.93Å; F92-I176 HydrophobicContact CE1-CD1 4.32Å
93	I	95.1	Very high	95.2	Very high	3 Å²	3	33.2 Å²	33.2	2%	0.015	16%	0.16	C	C	.	.	H	α-helix	trans	-60.5	-42.6	173.6	-72.2	170.6	0	0	0	110.8	V75 T89 N90 N95 L96 S97 I148 M305 Y364 F371	V75-I93 HydrophobicContact CG1-CG2 3.53Å; T89-I93 HydrophobicContact CG2-CD1 4.03Å; T89-I93 HydrophobicContact CG2-CG1 4.41Å; T89-I93 WeakPolarHBondContact O-CG1 3.49Å; T89-I93 PolarHBondContact O-N 3.37Å; N90-I93 PolarHBondContact O-N 3.48Å; I93-N95 VanDerWaalsContact C-N 3.34Å; I93-N95 PolarHBondContact O-N 2.8Å; I93-L96 WeakPolarHBondContact O-CB 3.43Å; I93-L96 PolarHBondContact O-N 3.04Å; I93-S97 PolarHBondContact O-N 3Å; I93-S97 PolarHBondContact O-OG 3.05Å; I93-I148 HydrophobicContact CG1-CD1 4.49Å; I93-M305 HydrophobicContact CD1-CE 4.34Å; I93-Y364 HydrophobicContact CG2-CD2 4.04Å; I93-Y364 HydrophobicContact CG2-CE2 3.42Å; I93-Y364 VanDerWaalsContact CG2-CE2 3.42Å; I93-F371 HydrophobicContact CD1-CE2 4.12Å; I93-F371 HydrophobicContact CD1-CZ 4.46Å; I93-F371 HydrophobicContact CG2-CZ 4.07Å
94	V	97.8	Very high	95.6	Very high	8 Å²	8	26.3 Å²	26.3	5%	0.048	13%	0.128	C	C	.	.	H	α-helix	trans	-62	-41.7	173.3	170	0	0	0	0	111.4	V79 W80 N90 Y91 F92 L96 S97 L98	V79-V94 HydrophobicContact CB-CG2 3.57Å; V79-V94 HydrophobicContact CG1-CG2 3.73Å; V79-V94 HydrophobicContact CG2-CG2 3.78Å; W80-V94 HydrophobicContact CZ2-CG1 3.95Å; N90-V94 VanDerWaalsContact O-CG2 3.32Å; N90-V94 WeakPolarHBondContact O-CG2 3.37Å; N90-V94 PolarHBondContact O-N 3.2Å; Y91-V94 PolarHBondContact O-N 2.89Å; F92-V94 VanDerWaalsContact C-N 3.32Å; F92-V94 PolarHBondContact O-N 3.32Å; V94-L96 VanDerWaalsContact C-N 3.31Å; V94-L96 PolarHBondContact O-N 3.32Å; V94-S97 PolarHBondContact O-N 3.41Å; V94-L98 HydrophobicContact CG1-CD1 4.16Å; V94-L98 HydrophobicContact CG1-CG 4.39Å; V94-L98 WeakPolarHBondContact O-CG 3.31Å; V94-L98 PolarHBondContact O-N 3.13Å
95	N	98.1	Very high	96	Very high	5 Å²	5	26.1 Å²	26.1	3%	0.027	13%	0.129	C	C	.	.	H	α-helix	trans	-59.1	-43.2	176.1	-170	58.8	0	0	0	112.1	Y91 F92 I93 L98 A99 T144 I173 W177	Y91-N95 PolarHBondContact O-N 3.23Å; F92-N95 WeakPolarHBondContact O-CB 3.45Å; F92-N95 PolarHBondContact O-N 3.45Å; F92-N95 VanDerWaalsContact O-N 3.15Å; I93-N95 VanDerWaalsContact C-N 3.34Å; I93-N95 PolarHBondContact O-N 2.8Å; N95-L98 PolarHBondContact O-N 3.3Å; N95-A99 PolarHBondContact O-N 3.15Å; N95-A99 VanDerWaalsContact O-N 3.12Å; N95-T144 HydrophobicContact CB-CG2 4.43Å; N95-T144 PolarHBondContact ND2-OG1 2.85Å; N95-I173 HydrophobicContact CB-CD1 4.12Å; N95-I173 HydrophobicContact CB-CG1 4.12Å; N95-I173 HydrophobicContact CB-CG2 4.39Å; N95-I173 VanDerWaalsContact OD1-CG2 3.27Å; N95-I173 WeakPolarHBondContact OD1-CG2 3.26Å; N95-W177 PolarHBondContact OD1-NE1 2.79Å
96	L	96.6	Very high	96.2	Very high	2 Å²	2	28.3 Å²	28.3	1%	0.01	14%	0.143	C	C	.	.	H	α-helix	trans	-61.8	-47.1	175.8	-170.4	65.3	0	0	0	111	F92 I93 V94 L98 A99 D100 S141 T144 L145	F92-L96 PolarHBondContact O-N 2.74Å; I93-L96 WeakPolarHBondContact O-CB 3.43Å; I93-L96 PolarHBondContact O-N 3.04Å; V94-L96 VanDerWaalsContact C-N 3.31Å; V94-L96 PolarHBondContact O-N 3.32Å; L96-L98 VanDerWaalsContact C-N 3.3Å; L96-L98 PolarHBondContact O-N 3.32Å; L96-A99 PolarHBondContact O-N 3.36Å; L96-D100 PolarHBondContact O-N 3.24Å; L96-S141 WeakPolarHBondContact CD1-OG 3.26Å; L96-T144 HydrophobicContact CB-CG2 4.23Å; L96-L145 HydrophobicContact CD2-CD2 4.11Å
97	S	97.8	Very high	96.4	Very high	0 Å²	0	23 Å²	23	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-61.8	-33.7	176.7	-71.7	0	0	0	0	113.6	N72 V75 I93 V94 V101	N72-S97 WeakPolarHBondContact OD1-CA 3.42Å; N72-S97 WeakPolarHBondContact OD1-CB 3.32Å; N72-S97 PolarHBondContact OD1-OG 3.27Å; V75-S97 WeakPolarHBondContact CB-OG 3.35Å; V75-S97 VanDerWaalsContact CG1-OG 3.31Å; V75-S97 WeakPolarHBondContact CG1-OG 3.42Å; I93-S97 PolarHBondContact O-N 3Å; I93-S97 PolarHBondContact O-OG 3.05Å; V94-S97 PolarHBondContact O-N 3.41Å; S97-V101 WeakPolarHBondContact O-CB 3.35Å; S97-V101 VanDerWaalsContact O-CG2 3.23Å; S97-V101 WeakPolarHBondContact O-CG2 3.15Å; S97-V101 PolarHBondContact O-N 3.43Å
98	L	98.1	Very high	96.7	Very high	73 Å²	73	20.5 Å²	20.5	38%	0.382	11%	0.107	S	C	.	.	H	α-helix	trans	-69	-40.5	174.6	-71	172.3	0	0	0	112.2	W80 V94 N95 L96 V101 L102	W80-L98 HydrophobicContact CH2-CD2 4.25Å; W80-L98 HydrophobicContact CZ2-CD2 4.49Å; V94-L98 HydrophobicContact CG1-CD1 4.16Å; V94-L98 HydrophobicContact CG1-CG 4.39Å; V94-L98 WeakPolarHBondContact O-CG 3.31Å; V94-L98 PolarHBondContact O-N 3.13Å; N95-L98 PolarHBondContact O-N 3.3Å; L96-L98 VanDerWaalsContact C-N 3.3Å; L96-L98 PolarHBondContact O-N 3.32Å; L98-V101 PolarHBondContact O-N 3.49Å; L98-L102 PolarHBondContact O-N 3.45Å
99	A	97.8	Very high	96.9	Very high	0 Å²	0	22.1 Å²	22.1	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-65.2	-40.5	175	0	0	0	0	0	111.5	N95 L96 L102 V103 S137 V140	N95-A99 PolarHBondContact O-N 3.15Å; N95-A99 VanDerWaalsContact O-N 3.12Å; L96-A99 PolarHBondContact O-N 3.36Å; A99-L102 WeakPolarHBondContact O-CB 3.38Å; A99-L102 PolarHBondContact O-N 3.22Å; A99-V103 PolarHBondContact O-N 3.25Å; A99-S137 PolarHBondContact O-OG 3.41Å; A99-V140 HydrophobicContact CB-CB 4.33Å; A99-V140 HydrophobicContact CB-CG1 3.88Å
100	D	97.9	Very high	97.2	Very high	1 Å²	1	22 Å²	22	1%	0.005	12%	0.118	C	C	.	.	H	α-helix	trans	-64.1	-43.2	174.8	-79.2	-29	0	0	0	112	L96 L102 V103 T104 S357 N360	L96-D100 PolarHBondContact O-N 3.24Å; D100-L102 VanDerWaalsContact C-N 3.35Å; D100-L102 PolarHBondContact O-N 3.42Å; D100-V103 VanDerWaalsContact O-CG2 3.25Å; D100-V103 WeakPolarHBondContact O-CG2 3.36Å; D100-V103 PolarHBondContact O-N 2.87Å; D100-T104 VanDerWaalsContact O-CB 3.27Å; D100-T104 WeakPolarHBondContact O-CB 3.36Å; D100-T104 PolarHBondContact O-N 3.43Å; D100-T104 PolarHBondContact O-OG1 3.14Å; D100-S357 VanDerWaalsContact CG-OG 3.32Å; D100-S357 WeakPolarHBondContact OD1-CB 3.16Å; D100-S357 PolarHBondContact OD1-OG 3.47Å; D100-N360 PolarHBondContact OD2-ND2 3.35Å
101	V	98.4	Very high	97.3	Very high	25 Å²	25	21.9 Å²	21.9	15%	0.152	12%	0.117	C	C	.	.	H	α-helix	trans	-62.3	-42.5	175.6	166.3	0	0	0	0	111.2	L69 N72 V73 S97 L98 V103 T104 I105	L69-V101 HydrophobicContact CD1-CG1 4.34Å; N72-V101 HydrophobicContact CB-CG2 3.64Å; V73-V101 HydrophobicContact CG2-CG2 4.29Å; S97-V101 WeakPolarHBondContact O-CB 3.35Å; S97-V101 VanDerWaalsContact O-CG2 3.23Å; S97-V101 WeakPolarHBondContact O-CG2 3.15Å; S97-V101 PolarHBondContact O-N 3.43Å; L98-V101 PolarHBondContact O-N 3.49Å; V101-V103 PolarHBondContact O-N 2.93Å; V101-T104 PolarHBondContact O-N 3.28Å; V101-I105 HydrophobicContact CG1-CD1 3.67Å; V101-I105 HydrophobicContact CG1-CG1 4.42Å; V101-I105 WeakPolarHBondContact O-CG1 3.41Å; V101-I105 PolarHBondContact O-N 3.37Å
102	L	97.3	Very high	97.3	Very high	47 Å²	47	20 Å²	20	25%	0.246	11%	0.112	C	C	.	.	H	α-helix	trans	-55.9	-52.5	177.3	174.5	64.6	0	0	0	111.1	L98 A99 D100 I105 T106 L133 W177	L98-L102 PolarHBondContact O-N 3.45Å; A99-L102 WeakPolarHBondContact O-CB 3.38Å; A99-L102 PolarHBondContact O-N 3.22Å; D100-L102 VanDerWaalsContact C-N 3.35Å; D100-L102 PolarHBondContact O-N 3.42Å; L102-I105 PolarHBondContact O-N 3.39Å; L102-T106 HydrophobicContact CD1-CG2 4.15Å; L102-T106 WeakPolarHBondContact O-CB 3.33Å; L102-T106 PolarHBondContact O-N 3.11Å; L102-T106 PolarHBondContact O-OG1 3.23Å; L102-L133 HydrophobicContact CD2-CD2 4.38Å; L102-W177 HydrophobicContact CD2-CH2 4.1Å; L102-W177 HydrophobicContact CD2-CZ3 4.35Å
103	V	97.4	Very high	97.1	Very high	9 Å²	9	23.3 Å²	23.3	6%	0.055	13%	0.129	C	C	.	.	H	α-helix	trans	-71.6	-32.4	-179.2	-65.8	0	0	0	0	113.1	A99 D100 V101 I105 C107 L108 S137 Y354	A99-V103 PolarHBondContact O-N 3.25Å; D100-V103 VanDerWaalsContact O-CG2 3.25Å; D100-V103 WeakPolarHBondContact O-CG2 3.36Å; D100-V103 PolarHBondContact O-N 2.87Å; V101-V103 PolarHBondContact O-N 2.93Å; V103-I105 VanDerWaalsContact C-N 3.32Å; V103-I105 PolarHBondContact O-N 3.3Å; V103-C107 HydrophobicContact CB-CB 4.23Å; V103-C107 WeakPolarHBondContact O-CA 3.21Å; V103-C107 WeakPolarHBondContact O-CB 3.38Å; V103-C107 PolarHBondContact O-N 3.43Å; V103-L108 PolarHBondContact O-N 3.44Å; V103-S137 VanDerWaalsContact CG1-OG 3.29Å; V103-S137 WeakPolarHBondContact CG1-OG 3.47Å; V103-Y354 HydrophobicContact CB-CE1 4.38Å
104	T	98.3	Very high	97	Very high	1 Å²	1	25.1 Å²	25.1	1%	0.006	14%	0.14	C	C	.	.	H	α-helix	trans	-63.1	-41.2	176.5	-58.5	0	0	0	0	110.8	F65 A68 L69 D100 V101 L108	F65-T104 HydrophobicContact CD2-CG2 3.74Å; F65-T104 VanDerWaalsContact CD2-O 3.3Å; F65-T104 WeakPolarHBondContact CD2-O 3.46Å; F65-T104 HydrophobicContact CE2-CG2 4.14Å; F65-T104 WeakPolarHBondContact CE2-O 3.37Å; F65-T104 HydrophobicContact CG-CG2 4.27Å; A68-T104 HydrophobicContact CB-CG2 3.98Å; L69-T104 HydrophobicContact CB-CG2 4.19Å; D100-T104 VanDerWaalsContact O-CB 3.27Å; D100-T104 WeakPolarHBondContact O-CB 3.36Å; D100-T104 PolarHBondContact O-N 3.43Å; D100-T104 PolarHBondContact O-OG1 3.14Å; V101-T104 PolarHBondContact O-N 3.28Å; T104-L108 HydrophobicContact CG2-CD1 4.35Å; T104-L108 WeakPolarHBondContact O-CB 3.24Å
105	I	97.8	Very high	96.8	Very high	92 Å²	92	25.1 Å²	25.1	47%	0.472	14%	0.14	S	C	.	.	H	α-helix	trans	-79.5	-41.8	-179.1	-66.2	172.8	0	0	0	111.7	L69 V101 L102 V103	L69-I105 HydrophobicContact CD1-CD1 3.9Å; L69-I105 HydrophobicContact CD1-CG1 3.9Å; V101-I105 HydrophobicContact CG1-CD1 3.67Å; V101-I105 HydrophobicContact CG1-CG1 4.42Å; V101-I105 WeakPolarHBondContact O-CG1 3.41Å; V101-I105 PolarHBondContact O-N 3.37Å; L102-I105 PolarHBondContact O-N 3.39Å; V103-I105 VanDerWaalsContact C-N 3.32Å; V103-I105 PolarHBondContact O-N 3.3Å
106	T	96.1	Very high	96.4	Very high	48 Å²	48	26 Å²	26	29%	0.294	15%	0.145	S	C	.	.	H	α-helix	trans	-98	-40.3	-167.9	60.1	0	0	0	0	114.1	L102	L102-T106 HydrophobicContact CD1-CG2 4.15Å; L102-T106 WeakPolarHBondContact O-CB 3.33Å; L102-T106 PolarHBondContact O-N 3.11Å; L102-T106 PolarHBondContact O-OG1 3.23Å
107	C	97.8	Very high	96	Very high	0 Å²	0	26.4 Å²	26.4	0%	0	15%	0.147	C	C	.	.	T	Hydrogen-bonded Turn	trans	-95.1	-44.5	-172.3	-54.7	0	0	0	0	111.9	V103 A110 T111 I130 Q134 Y354	V103-C107 HydrophobicContact CB-CB 4.23Å; V103-C107 WeakPolarHBondContact O-CA 3.21Å; V103-C107 WeakPolarHBondContact O-CB 3.38Å; V103-C107 PolarHBondContact O-N 3.43Å; C107-A110 PolarHBondContact O-N 3.33Å; C107-A110 VanDerWaalsContact O-N 3.14Å; C107-T111 PolarHBondContact O-N 3.27Å; C107-T111 PolarHBondContact O-OG1 2.94Å; C107-I130 HydrophobicContact CB-CG2 4.32Å; C107-Q134 HydrophobicContact CB-CB 4.41Å; C107-Y354 HydrophobicContact CB-CE1 4.15Å; C107-Y354 VanDerWaalsContact CB-OH 3.32Å; C107-Y354 WeakPolarHBondContact CB-OH 3.43Å
108	L	97.9	Very high	95.6	Very high	4 Å²	4	30.9 Å²	30.9	2%	0.021	17%	0.168	C	C	.	.	H	α-helix	trans	-56.4	-48.4	-173.5	-173.5	167.8	0	0	0	113.2	Y61 V64 F65 V103 T104 A110 T111 L112 Y354	Y61-L108 HydrophobicContact CD1-CD1 4.48Å; Y61-L108 HydrophobicContact CD1-CD2 3.66Å; Y61-L108 HydrophobicContact CD1-CG 3.81Å; Y61-L108 HydrophobicContact CE1-CD2 4.44Å; Y61-L108 HydrophobicContact CE1-CG 4.23Å; V64-L108 HydrophobicContact CG1-CD1 4.05Å; F65-L108 HydrophobicContact CB-CD1 4.03Å; F65-L108 HydrophobicContact CB-CD2 4.11Å; F65-L108 HydrophobicContact CD2-CD1 4.26Å; F65-L108 HydrophobicContact CD2-CD2 4.03Å; V103-L108 PolarHBondContact O-N 3.44Å; T104-L108 HydrophobicContact CG2-CD1 4.35Å; T104-L108 WeakPolarHBondContact O-CB 3.24Å; L108-A110 VanDerWaalsContact C-N 3.3Å; L108-A110 PolarHBondContact O-N 3.34Å; L108-T111 PolarHBondContact O-N 3.41Å; L108-L112 WeakPolarHBondContact O-CB 3.4Å; L108-L112 PolarHBondContact O-N 3.29Å; L108-Y354 HydrophobicContact CB-CD1 3.94Å; L108-Y354 HydrophobicContact CB-CE1 3.91Å; L108-Y354 HydrophobicContact CB-CG 4.28Å; L108-Y354 HydrophobicContact CD1-CD1 4.21Å; L108-Y354 HydrophobicContact CD1-CG 4.07Å; L108-Y354 HydrophobicContact CG-CD1 4.21Å; L108-Y354 HydrophobicContact CG-CD2 4.3Å; L108-Y354 HydrophobicContact CG-CG 4.07Å
109	P	97.1	Very high	95.2	Very high	50 Å²	50	27.5 Å²	27.5	33%	0.325	15%	0.151	S	C	.	.	H	α-helix	trans	-63.7	-36.6	179.5	-22	34.8	0	0	0	112.8	F65 L113	F65-P109 HydrophobicContact CE2-CG 4.13Å; P109-L113 PolarHBondContact O-N 3.15Å; P109-L113 VanDerWaalsContact O-N 3.11Å
110	A	96.7	Very high	95	Very high	3 Å²	3	28.2 Å²	28.2	3%	0.025	15%	0.153	C	C	.	.	H	α-helix	trans	-70.5	-42.9	177.9	0	0	0	0	0	111.6	C107 L108 L113 V114 F122 I130	C107-A110 PolarHBondContact O-N 3.33Å; C107-A110 VanDerWaalsContact O-N 3.14Å; L108-A110 VanDerWaalsContact C-N 3.3Å; L108-A110 PolarHBondContact O-N 3.34Å; A110-L113 PolarHBondContact O-N 3.25Å; A110-V114 VanDerWaalsContact O-CG2 3.32Å; A110-V114 WeakPolarHBondContact O-CG2 3.34Å; A110-V114 PolarHBondContact O-N 2.96Å; A110-F122 HydrophobicContact CB-CD2 4.2Å; A110-F122 HydrophobicContact CB-CE2 3.61Å; A110-F122 HydrophobicContact CB-CZ 3.9Å; A110-I130 HydrophobicContact CB-CD1 3.68Å; A110-I130 HydrophobicContact CB-CG2 4.17Å
111	T	96.3	Very high	94.6	Very high	14 Å²	14	31.5 Å²	31.5	9%	0.086	17%	0.168	C	C	.	.	H	α-helix	trans	-63.2	-43.4	175.1	-56.6	0	0	0	0	111.5	C107 L108 L113 V114 D115 H350 Y354	C107-T111 PolarHBondContact O-N 3.27Å; C107-T111 PolarHBondContact O-OG1 2.94Å; L108-T111 PolarHBondContact O-N 3.41Å; T111-L113 VanDerWaalsContact C-N 3.31Å; T111-L113 PolarHBondContact O-N 3.46Å; T111-V114 PolarHBondContact O-N 3.35Å; T111-D115 VanDerWaalsContact O-CB 3.27Å; T111-D115 WeakPolarHBondContact O-CB 3.28Å; T111-D115 VanDerWaalsContact O-CG 3.29Å; T111-D115 PolarHBondContact O-N 2.92Å; T111-H350 HydrophobicContact CG2-CB 3.93Å; T111-Y354 HydrophobicContact CG2-CE2 3.87Å; T111-Y354 PolarHBondContact OG1-OH 3.42Å
112	L	95.8	Very high	94.4	Very high	29 Å²	29	33.6 Å²	33.6	15%	0.152	18%	0.175	C	C	.	.	H	α-helix	trans	-56.4	-47	174.5	170.2	62.6	0	0	0	111.2	I58 Y61 L108 V114 D115 I116	I58-L112 HydrophobicContact CG1-CD1 4.1Å; Y61-L112 HydrophobicContact CD1-CB 4.23Å; Y61-L112 HydrophobicContact CD2-CB 4.43Å; Y61-L112 HydrophobicContact CD2-CD1 3.57Å; Y61-L112 HydrophobicContact CE2-CD1 4.16Å; Y61-L112 HydrophobicContact CG-CB 4.18Å; Y61-L112 HydrophobicContact CG-CD1 3.87Å; Y61-L112 HydrophobicContact CG-CG 4.41Å; L108-L112 WeakPolarHBondContact O-CB 3.4Å; L108-L112 PolarHBondContact O-N 3.29Å; L112-V114 VanDerWaalsContact C-N 3.35Å; L112-V114 PolarHBondContact O-N 2.78Å; L112-D115 PolarHBondContact O-N 3.12Å; L112-I116 HydrophobicContact CD1-CD1 4.36Å; L112-I116 HydrophobicContact CD1-CG1 3.75Å; L112-I116 WeakPolarHBondContact O-CB 3.36Å; L112-I116 WeakPolarHBondContact O-CG1 3.34Å; L112-I116 PolarHBondContact O-N 3.49Å
113	L	93.5	Very high	94.1	Very high	75 Å²	75	33.1 Å²	33.1	39%	0.393	18%	0.181	S	C	.	.	H	α-helix	trans	-62.9	-42.1	179.6	-80.5	166.1	0	0	0	111.9	P109 A110 T111 I116 T117 F122	P109-L113 PolarHBondContact O-N 3.15Å; P109-L113 VanDerWaalsContact O-N 3.11Å; A110-L113 PolarHBondContact O-N 3.25Å; T111-L113 VanDerWaalsContact C-N 3.31Å; T111-L113 PolarHBondContact O-N 3.46Å; L113-I116 PolarHBondContact O-N 3.4Å; L113-T117 WeakPolarHBondContact O-CB 3.43Å; L113-T117 WeakPolarHBondContact O-CG2 3.14Å; L113-T117 PolarHBondContact O-N 2.87Å; L113-T117 PolarHBondContact O-OG1 3.21Å; L113-F122 HydrophobicContact CB-CE2 4.44Å; L113-F122 HydrophobicContact CB-CZ 4.34Å; L113-F122 HydrophobicContact CD1-CE1 4.32Å; L113-F122 HydrophobicContact CD1-CE2 4.44Å; L113-F122 HydrophobicContact CD1-CZ 3.56Å
114	V	93.2	Very high	93.9	Very high	41 Å²	41	36.5 Å²	36.5	25%	0.248	20%	0.196	C	C	.	.	H	α-helix	trans	-66.2	-45.2	176.4	174	0	0	0	0	111.5	A110 T111 L112 I116 T117 E118 W120 Y343	A110-V114 VanDerWaalsContact O-CG2 3.32Å; A110-V114 WeakPolarHBondContact O-CG2 3.34Å; A110-V114 PolarHBondContact O-N 2.96Å; T111-V114 PolarHBondContact O-N 3.35Å; L112-V114 VanDerWaalsContact C-N 3.35Å; L112-V114 PolarHBondContact O-N 2.78Å; V114-I116 PolarHBondContact O-N 3.21Å; V114-T117 PolarHBondContact O-N 2.65Å; V114-E118 VanDerWaalsContact O-CA 3.24Å; V114-E118 WeakPolarHBondContact O-CA 3.41Å; V114-E118 PolarHBondContact O-N 3.19Å; V114-W120 HydrophobicContact CG2-CE3 3.49Å; V114-W120 VanDerWaalsContact CG2-CE3 3.49Å; V114-W120 HydrophobicContact CG2-CZ3 3.86Å; V114-Y343 PolarHBondContact O-OH 2.88Å; V114-Y343 VanDerWaalsContact O-OH 3.09Å
115	D	92.3	Very high	93.8	Very high	8 Å²	8	41 Å²	41	4%	0.043	23%	0.228	C	C	.	.	H	α-helix	trans	-63.9	-25.8	-178.8	-77.3	-2.4	0	0	0	112.2	Y61 T111 L112 Y343 T347 H350	Y61-D115 PolarHBondContact OH-OD2 3.47Å; T111-D115 VanDerWaalsContact O-CB 3.27Å; T111-D115 WeakPolarHBondContact O-CB 3.28Å; T111-D115 VanDerWaalsContact O-CG 3.29Å; T111-D115 PolarHBondContact O-N 2.92Å; L112-D115 PolarHBondContact O-N 3.12Å; D115-Y343 WeakPolarHBondContact CA-OH 3.44Å; D115-Y343 VanDerWaalsContact O-CE1 3.24Å; D115-Y343 WeakPolarHBondContact O-CE1 3.27Å; D115-Y343 PolarHBondContact O-OH 3.47Å; D115-T347 HydrophobicContact CB-CG2 3.84Å; D115-H350 IonicContact OD1-CE1 2.9Å; D115-H350 IonicContact OD1-ND1 2.74Å; D115-H350 PolarHBondContact OD1-ND1 3.43Å; D115-H350 IonicContact OD2-CG 3.49Å; D115-H350 IonicContact OD2-ND1 3.72Å; D115-H350 PolarHBondContact OD2-ND1 2.84Å
116	I	90.9	Very high	93.7	Very high	24 Å²	24	40 Å²	40	12%	0.123	22%	0.223	C	C	.	.	H	α-helix	trans	-91.5	-45.1	177.8	-63.6	-71.1	0	0	0	112	P50 E54 L57 I58 L112 L113 V114	P50-I116 HydrophobicContact CG-CG2 4.45Å; E54-I116 HydrophobicContact CB-CD1 3.71Å; E54-I116 HydrophobicContact CG-CD1 4.1Å; L57-I116 HydrophobicContact CD2-CD1 3.88Å; I58-I116 HydrophobicContact CD1-CD1 4Å; I58-I116 HydrophobicContact CD1-CG1 4.47Å; I58-I116 HydrophobicContact CG1-CD1 3.69Å; I58-I116 HydrophobicContact CG1-CG1 4.1Å; L112-I116 HydrophobicContact CD1-CD1 4.36Å; L112-I116 HydrophobicContact CD1-CG1 3.75Å; L112-I116 WeakPolarHBondContact O-CB 3.36Å; L112-I116 WeakPolarHBondContact O-CG1 3.34Å; L112-I116 PolarHBondContact O-N 3.49Å; L113-I116 PolarHBondContact O-N 3.4Å; V114-I116 PolarHBondContact O-N 3.21Å
117	T	88.2	Confident	93.8	Very high	11 Å²	11	37.8 Å²	37.8	7%	0.067	21%	0.209	C	C	.	.	H	α-helix	trans	-97.1	-5.8	-169.3	66.2	0	0	0	0	113.7	L48 L113 V114 T119 F121	L48-T117 HydrophobicContact CD2-CG2 3.67Å; L48-T117 HydrophobicContact CG-CG2 3.98Å; L113-T117 WeakPolarHBondContact O-CB 3.43Å; L113-T117 WeakPolarHBondContact O-CG2 3.14Å; L113-T117 PolarHBondContact O-N 2.87Å; L113-T117 PolarHBondContact O-OG1 3.21Å; V114-T117 PolarHBondContact O-N 2.65Å; T117-T119 WeakPolarHBondContact O-CB 3.27Å; T117-T119 PolarHBondContact O-N 2.89Å; T117-T119 PolarHBondContact O-OG1 3.45Å; T117-T119 PolarHBondContact OG1-N 2.93Å; T117-T119 PolarHBondContact OG1-O 3.17Å; T117-F121 HydrophobicContact CG2-CE2 4.02Å; T117-F121 WeakPolarHBondContact OG1-CE2 3.42Å
118	E	88.8	Confident	93.8	Very high	94 Å²	94	40.6 Å²	40.6	44%	0.439	22%	0.222	S	C	.	.	S	Bend	trans	52.6	16.3	-170.7	-66.7	-176.4	-143.7	0	0	113.5	V114 Y343	V114-E118 VanDerWaalsContact O-CA 3.24Å; V114-E118 WeakPolarHBondContact O-CA 3.41Å; V114-E118 PolarHBondContact O-N 3.19Å; E118-Y343 HydrophobicContact CG-CE1 4.16Å; E118-Y343 HydrophobicContact CG-CE2 3.87Å; E118-Y343 VanDerWaalsContact CG-OH 3.28Å; E118-Y343 WeakPolarHBondContact CG-OH 3.41Å
119	T	89.4	Confident	93.8	Very high	2 Å²	2	43.6 Å²	43.6	1%	0.012	24%	0.24	C	C	.	.			trans	-130.2	143	-168.2	-60.4	0	0	0	0	111.2	T117 F121 F207 T208	T117-T119 WeakPolarHBondContact O-CB 3.27Å; T117-T119 PolarHBondContact O-N 2.89Å; T117-T119 PolarHBondContact O-OG1 3.45Å; T117-T119 PolarHBondContact OG1-N 2.93Å; T117-T119 PolarHBondContact OG1-O 3.17Å; T119-F121 HydrophobicContact CG2-CD1 4.24Å; T119-F121 HydrophobicContact CG2-CD2 4.44Å; T119-F121 HydrophobicContact CG2-CE1 3.79Å; T119-F121 HydrophobicContact CG2-CE2 4.02Å; T119-F121 HydrophobicContact CG2-CZ 3.67Å; T119-F207 PolarHBondContact OG1-N 3.01Å; T119-T208 CarbonylContact C-O 3.59Å
120	W	93.3	Very high	93.9	Very high	15 Å²	15	41.8 Å²	41.8	6%	0.057	23%	0.228	C	C	.	.			trans	-99.1	108.5	175.1	-175.7	-97.1	0	0	0	111.9	V114 F122 G123 L126 C127 I130 C193 T208 C210	V114-W120 HydrophobicContact CG2-CE3 3.49Å; V114-W120 VanDerWaalsContact CG2-CE3 3.49Å; V114-W120 HydrophobicContact CG2-CZ3 3.86Å; W120-F122 HydrophobicContact CD2-CD2 4.09Å; W120-F122 AromaticContact CE2-CD2 3.94Å; W120-F122 HydrophobicContact CE3-CD2 4.06Å; W120-F122 HydrophobicContact CH2-CB 4.34Å; W120-F122 AromaticContact CH2-CD2 3.76Å; W120-F122 HydrophobicContact CH2-CD2 3.76Å; W120-F122 HydrophobicContact CH2-CG 4.43Å; W120-F122 HydrophobicContact CZ2-CB 3.58Å; W120-F122 AromaticContact CZ2-CD2 3.77Å; W120-F122 HydrophobicContact CZ2-CD2 3.77Å; W120-F122 HydrophobicContact CZ2-CG 4.11Å; W120-F122 AromaticContact CZ3-CD2 3.91Å; W120-F122 HydrophobicContact CZ3-CD2 3.91Å; W120-F122 HydrophobicContact CZ3-CE2 4.44Å; W120-G123 PolarHBondContact NE1-O 3.31Å; W120-L126 HydrophobicContact CZ2-CB 3.96Å; W120-C127 VanDerWaalsContact CZ2-CA 3.45Å; W120-C127 HydrophobicContact CZ2-CB 4.1Å; W120-C127 VanDerWaalsContact CZ2-N 3.28Å; W120-I130 HydrophobicContact CH2-CB 4.06Å; W120-I130 HydrophobicContact CH2-CD1 3.76Å; W120-I130 HydrophobicContact CH2-CG1 4.44Å; W120-I130 HydrophobicContact CH2-CG2 4.29Å; W120-I130 HydrophobicContact CZ2-CD1 4.26Å; W120-C193 VanDerWaalsContact CD1-SG 3.54Å; W120-T208 WeakPolarHBondContact CB-O 3.26Å; W120-T208 PolarHBondContact N-O 3.17Å; W120-C210 HydrophobicContact CB-CB 3.93Å; W120-C210 HydrophobicContact CD2-CB 3.55Å; W120-C210 HydrophobicContact CE3-CB 3.8Å; W120-C210 HydrophobicContact CG-CB 3.58Å
121	F	90.9	Very high	93.9	Very high	70 Å²	70	42.6 Å²	42.6	31%	0.307	23%	0.233	S	C	.	.			trans	-94.1	-11.5	-178.3	-64.8	-73.3	0	0	0	115.2	L48 T117 T119 G123	L48-F121 HydrophobicContact CD2-CZ 4.39Å; T117-F121 HydrophobicContact CG2-CE2 4.02Å; T117-F121 WeakPolarHBondContact OG1-CE2 3.42Å; T119-F121 HydrophobicContact CG2-CD1 4.24Å; T119-F121 HydrophobicContact CG2-CD2 4.44Å; T119-F121 HydrophobicContact CG2-CE1 3.79Å; T119-F121 HydrophobicContact CG2-CE2 4.02Å; T119-F121 HydrophobicContact CG2-CZ 3.67Å; F121-G123 VanDerWaalsContact C-N 3.35Å; F121-G123 PolarHBondContact O-N 3.41Å
122	F	92.9	Very high	94	Very high	68 Å²	68	44.3 Å²	44.3	30%	0.298	24%	0.238	S	C	.	.	S	Bend	trans	-91.5	6.1	-164.5	-52	-80.4	0	0	0	114.6	A110 L113 W120 L126	A110-F122 HydrophobicContact CB-CD2 4.2Å; A110-F122 HydrophobicContact CB-CE2 3.61Å; A110-F122 HydrophobicContact CB-CZ 3.9Å; L113-F122 HydrophobicContact CB-CE2 4.44Å; L113-F122 HydrophobicContact CB-CZ 4.34Å; L113-F122 HydrophobicContact CD1-CE1 4.32Å; L113-F122 HydrophobicContact CD1-CE2 4.44Å; L113-F122 HydrophobicContact CD1-CZ 3.56Å; W120-F122 HydrophobicContact CD2-CD2 4.09Å; W120-F122 AromaticContact CE2-CD2 3.94Å; W120-F122 HydrophobicContact CE3-CD2 4.06Å; W120-F122 HydrophobicContact CH2-CB 4.34Å; W120-F122 AromaticContact CH2-CD2 3.76Å; W120-F122 HydrophobicContact CH2-CD2 3.76Å; W120-F122 HydrophobicContact CH2-CG 4.43Å; W120-F122 HydrophobicContact CZ2-CB 3.58Å; W120-F122 AromaticContact CZ2-CD2 3.77Å; W120-F122 HydrophobicContact CZ2-CD2 3.77Å; W120-F122 HydrophobicContact CZ2-CG 4.11Å; W120-F122 AromaticContact CZ3-CD2 3.91Å; W120-F122 HydrophobicContact CZ3-CD2 3.91Å; W120-F122 HydrophobicContact CZ3-CE2 4.44Å; F122-L126 HydrophobicContact CB-CB 3.75Å; F122-L126 HydrophobicContact CB-CD1 3.75Å; F122-L126 HydrophobicContact CB-CG 4.38Å
123	G	92.1	Very high	94.1	Very high	37 Å²	37	44.8 Å²	44.8	38%	0.381	24%	0.24	S	C	.	.	H	α-helix	trans	71.4	177.8	179.4	0	0	0	0	0	115	W120 F121 S125 C127	W120-G123 PolarHBondContact NE1-O 3.31Å; F121-G123 VanDerWaalsContact C-N 3.35Å; F121-G123 PolarHBondContact O-N 3.41Å; G123-S125 PolarHBondContact O-N 3Å; G123-C127 PolarHBondContact O-N 2.76Å; G123-C127 VanDerWaalsContact O-N 3.12Å
124	Q	93.1	Very high	94.3	Very high	80 Å²	80	43.4 Å²	43.4	37%	0.374	23%	0.232	S	C	.	.	H	α-helix	trans	-63.6	-40.5	-169.7	-177.8	62	27.5	0	0	113.9	C127 K128 C193	Q124-C127 WeakPolarHBondContact O-CB 3.35Å; Q124-C127 PolarHBondContact O-N 2.87Å; Q124-K128 PolarHBondContact O-N 2.89Å; Q124-C193 PolarHBondContact OE1-SG 3.48Å
125	S	96.2	Very high	94.4	Very high	95 Å²	95	42.1 Å²	42.1	66%	0.664	22%	0.224	S	C	*	.	H	α-helix	trans	-63.8	-47.7	-177.2	-55.4	0	0	0	0	111.5	G123 C127 K128 V129	G123-S125 PolarHBondContact O-N 3Å; S125-C127 VanDerWaalsContact C-N 3.3Å; S125-C127 PolarHBondContact O-N 3.27Å; S125-K128 PolarHBondContact O-N 3.29Å; S125-V129 WeakPolarHBondContact O-CG2 3.21Å; S125-V129 PolarHBondContact O-N 3.46Å
126	L	96.5	Very high	94.7	Very high	73 Å²	73	41.9 Å²	41.9	38%	0.382	22%	0.223	S	C	.	.	H	α-helix	trans	-72.2	-26	179.5	-70.1	174.7	0	0	0	112	W120 F122 K128 V129 I130	W120-L126 HydrophobicContact CZ2-CB 3.96Å; F122-L126 HydrophobicContact CB-CB 3.75Å; F122-L126 HydrophobicContact CB-CD1 3.75Å; F122-L126 HydrophobicContact CB-CG 4.38Å; L126-K128 PolarHBondContact O-N 2.91Å; L126-V129 HydrophobicContact CD2-CB 4.4Å; L126-V129 PolarHBondContact O-N 3.19Å; L126-I130 HydrophobicContact CB-CD1 4.05Å; L126-I130 HydrophobicContact CB-CG1 4.44Å; L126-I130 HydrophobicContact CD2-CD1 4.36Å; L126-I130 HydrophobicContact CD2-CG1 4.38Å; L126-I130 WeakPolarHBondContact O-CB 3.33Å; L126-I130 PolarHBondContact O-N 2.92Å
127	C	97.4	Very high	95	Very high	0 Å²	0	40.8 Å²	40.8	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-60.4	-29.1	171.9	174.4	0	0	0	0	112.1	W120 G123 Q124 S125 P131 M191 E192 C193 C210	W120-C127 VanDerWaalsContact CZ2-CA 3.45Å; W120-C127 HydrophobicContact CZ2-CB 4.1Å; W120-C127 VanDerWaalsContact CZ2-N 3.28Å; G123-C127 PolarHBondContact O-N 2.76Å; G123-C127 VanDerWaalsContact O-N 3.12Å; Q124-C127 WeakPolarHBondContact O-CB 3.35Å; Q124-C127 PolarHBondContact O-N 2.87Å; S125-C127 VanDerWaalsContact C-N 3.3Å; S125-C127 PolarHBondContact O-N 3.27Å; C127-P131 WeakPolarHBondContact O-CD 3.2Å; C127-P131 WeakPolarHBondContact O-CG 3.25Å; C127-M191 VanDerWaalsContact O-CB 3.27Å; C127-M191 WeakPolarHBondContact O-CB 3.4Å; C127-E192 VanDerWaalsContact SG-C 3.59Å; C127-C193 WeakPolarHBondContact CB-SG 3.27Å; C127-C193 VanDerWaalsContact SG-SG 3.62Å; C127-C210 WeakPolarHBondContact CA-SG 3.41Å; C127-C210 HydrophobicContact CB-CB 3.89Å; C127-C210 WeakPolarHBondContact CB-SG 3.36Å; C127-C210 PolarHBondContact O-SG 2.95Å; C127-C210 VanDerWaalsContact SG-CA 3.58Å; C127-C210 WeakPolarHBondContact SG-CB 3.49Å; C127-C210 CovalentContact SG-SG 2.03Å; C127-C210 PolarHBondContact SG-SG 3.48Å
128	K	98.1	Very high	95.4	Very high	60 Å²	60	41 Å²	41	26%	0.261	22%	0.219	S	C	.	.	H	α-helix	trans	-84.4	-45.7	171.7	-63.2	-174.9	172.9	-62.8	0	112.2	Q124 S125 L126 Y132 A188 I189 M191	Q124-K128 PolarHBondContact O-N 2.89Å; S125-K128 PolarHBondContact O-N 3.29Å; L126-K128 PolarHBondContact O-N 2.91Å; K128-Y132 WeakPolarHBondContact O-CB 3.38Å; K128-Y132 PolarHBondContact O-N 3.04Å; K128-A188 WeakPolarHBondContact CD-O 3.38Å; K128-A188 VanDerWaalsContact CG-O 3.31Å; K128-A188 WeakPolarHBondContact CG-O 3.4Å; K128-A188 PolarHBondContact NZ-O 3.42Å; K128-A188 VanDerWaalsContact NZ-O 3.12Å; K128-I189 PolarHBondContact NZ-O 3.26Å; K128-M191 HydrophobicContact CG-CB 4.3Å; K128-M191 WeakPolarHBondContact CG-O 3.43Å; K128-M191 PolarHBondContact NZ-O 2.89Å
129	V	98.1	Very high	95.8	Very high	66 Å²	66	36.6 Å²	36.6	40%	0.4	20%	0.198	S	C	.	.	H	α-helix	trans	-70.2	-45.1	-171.7	172.9	0	0	0	0	112.7	S125 L126 Y132 L133	S125-V129 WeakPolarHBondContact O-CG2 3.21Å; S125-V129 PolarHBondContact O-N 3.46Å; L126-V129 HydrophobicContact CD2-CB 4.4Å; L126-V129 PolarHBondContact O-N 3.19Å; V129-Y132 WeakPolarHBondContact O-CB 3.37Å; V129-Y132 PolarHBondContact O-N 3.42Å; V129-L133 HydrophobicContact CG1-CD1 3.76Å; V129-L133 HydrophobicContact CG1-CG 4.08Å; V129-L133 VanDerWaalsContact O-CG 3.32Å; V129-L133 WeakPolarHBondContact O-CG 3.45Å; V129-L133 PolarHBondContact O-N 3.48Å
130	I	97.9	Very high	96.2	Very high	13 Å²	13	36.5 Å²	36.5	7%	0.067	20%	0.198	C	C	.	.	H	α-helix	trans	-66.5	-50.4	-173.8	-72.5	172.3	0	0	0	111.7	C107 A110 W120 L126 Y132 L133 Q134	C107-I130 HydrophobicContact CB-CG2 4.32Å; A110-I130 HydrophobicContact CB-CD1 3.68Å; A110-I130 HydrophobicContact CB-CG2 4.17Å; W120-I130 HydrophobicContact CH2-CB 4.06Å; W120-I130 HydrophobicContact CH2-CD1 3.76Å; W120-I130 HydrophobicContact CH2-CG1 4.44Å; W120-I130 HydrophobicContact CH2-CG2 4.29Å; W120-I130 HydrophobicContact CZ2-CD1 4.26Å; L126-I130 HydrophobicContact CB-CD1 4.05Å; L126-I130 HydrophobicContact CB-CG1 4.44Å; L126-I130 HydrophobicContact CD2-CD1 4.36Å; L126-I130 HydrophobicContact CD2-CG1 4.38Å; L126-I130 WeakPolarHBondContact O-CB 3.33Å; L126-I130 PolarHBondContact O-N 2.92Å; I130-Y132 VanDerWaalsContact C-N 3.28Å; I130-Y132 PolarHBondContact O-N 2.88Å; I130-L133 PolarHBondContact O-N 3.44Å; I130-Q134 WeakPolarHBondContact O-CB 3.46Å; I130-Q134 PolarHBondContact O-N 2.93Å
131	P	97.3	Very high	96.4	Very high	20 Å²	20	35.8 Å²	35.8	13%	0.13	20%	0.195	C	C	.	.	H	α-helix	trans	-62.3	-34.4	174.2	-25.4	37.4	0	0	0	112.9	C127 Q134 T135 M191	C127-P131 WeakPolarHBondContact O-CD 3.2Å; C127-P131 WeakPolarHBondContact O-CG 3.25Å; P131-Q134 PolarHBondContact O-N 3.4Å; P131-T135 WeakPolarHBondContact O-CG2 3.34Å; P131-T135 PolarHBondContact O-N 2.97Å; P131-T135 PolarHBondContact O-OG1 3.48Å; P131-M191 HydrophobicContact CB-CE 4.24Å; P131-M191 HydrophobicContact CB-CG 3.9Å; P131-M191 HydrophobicContact CB-SD 4.17Å; P131-M191 HydrophobicContact CG-CE 3.85Å; P131-M191 HydrophobicContact CG-CG 4.04Å; P131-M191 HydrophobicContact CG-SD 4.37Å
132	Y	98.3	Very high	96.7	Very high	50 Å²	50	32.5 Å²	32.5	20%	0.196	18%	0.181	C	C	.	.	H	α-helix	trans	-63.5	-49.6	174.2	173.9	-104.4	0	0	0	112.3	K128 V129 I130 Q134 T135 V136 C181 M184 A188	K128-Y132 WeakPolarHBondContact O-CB 3.38Å; K128-Y132 PolarHBondContact O-N 3.04Å; V129-Y132 WeakPolarHBondContact O-CB 3.37Å; V129-Y132 PolarHBondContact O-N 3.42Å; I130-Y132 VanDerWaalsContact C-N 3.28Å; I130-Y132 PolarHBondContact O-N 2.88Å; Y132-Q134 VanDerWaalsContact C-N 3.26Å; Y132-Q134 PolarHBondContact O-N 3.43Å; Y132-T135 PolarHBondContact O-N 2.89Å; Y132-T135 PolarHBondContact O-OG1 3.4Å; Y132-T135 VanDerWaalsContact O-OG1 3.07Å; Y132-V136 HydrophobicContact CD1-CG2 4.29Å; Y132-V136 HydrophobicContact CD2-CG2 4.09Å; Y132-V136 HydrophobicContact CE1-CG2 3.91Å; Y132-V136 HydrophobicContact CE2-CG2 3.7Å; Y132-V136 HydrophobicContact CG-CG2 4.38Å; Y132-V136 WeakPolarHBondContact O-CB 3.5Å; Y132-V136 VanDerWaalsContact O-CG2 3.24Å; Y132-V136 WeakPolarHBondContact O-CG2 3.44Å; Y132-V136 PolarHBondContact O-N 3.22Å; Y132-C181 VanDerWaalsContact OH-CA 3.32Å; Y132-C181 WeakPolarHBondContact OH-CA 3.47Å; Y132-C181 WeakPolarHBondContact OH-CB 3.48Å; Y132-C181 PolarHBondContact OH-O 3Å; Y132-M184 HydrophobicContact CD2-CB 4.08Å; Y132-M184 WeakPolarHBondContact CD2-O 3.26Å; Y132-M184 HydrophobicContact CE2-CB 3.88Å; Y132-A188 HydrophobicContact CD2-CB 3.88Å; Y132-A188 HydrophobicContact CG-CB 4.09Å
133	L	97.9	Very high	96.9	Very high	39 Å²	39	31.4 Å²	31.4	20%	0.204	18%	0.178	C	C	.	.	H	α-helix	trans	-62.3	-37.3	177.6	-69.5	177.9	0	0	0	111.6	L102 V129 I130 S137	L102-L133 HydrophobicContact CD2-CD2 4.38Å; V129-L133 HydrophobicContact CG1-CD1 3.76Å; V129-L133 HydrophobicContact CG1-CG 4.08Å; V129-L133 VanDerWaalsContact O-CG 3.32Å; V129-L133 WeakPolarHBondContact O-CG 3.45Å; V129-L133 PolarHBondContact O-N 3.48Å; I130-L133 PolarHBondContact O-N 3.44Å; L133-S137 WeakPolarHBondContact O-CB 3.04Å; L133-S137 PolarHBondContact O-N 3.43Å
134	Q	97.3	Very high	97.1	Very high	45 Å²	45	29.7 Å²	29.7	21%	0.21	16%	0.16	C	C	.	.	H	α-helix	trans	-60.4	-53.9	174.9	-173.8	173.5	-11.2	0	0	110.9	C107 I130 P131 Y132 V136 S137 V138	C107-Q134 HydrophobicContact CB-CB 4.41Å; I130-Q134 WeakPolarHBondContact O-CB 3.46Å; I130-Q134 PolarHBondContact O-N 2.93Å; P131-Q134 PolarHBondContact O-N 3.4Å; Y132-Q134 VanDerWaalsContact C-N 3.26Å; Y132-Q134 PolarHBondContact O-N 3.43Å; Q134-V136 PolarHBondContact O-N 3.2Å; Q134-S137 PolarHBondContact O-N 3.26Å; Q134-V138 WeakPolarHBondContact O-CG2 3.25Å; Q134-V138 PolarHBondContact O-N 3.42Å
135	T	96.8	Very high	97.2	Very high	15 Å²	15	26.5 Å²	26.5	9%	0.092	15%	0.145	C	C	.	.	H	α-helix	trans	-67.4	-35.8	-178.7	57.2	0	0	0	0	113.1	P131 Y132 S137 V138 S139 M184 Q187 F227	P131-T135 WeakPolarHBondContact O-CG2 3.34Å; P131-T135 PolarHBondContact O-N 2.97Å; P131-T135 PolarHBondContact O-OG1 3.48Å; Y132-T135 PolarHBondContact O-N 2.89Å; Y132-T135 PolarHBondContact O-OG1 3.4Å; Y132-T135 VanDerWaalsContact O-OG1 3.07Å; T135-S137 VanDerWaalsContact C-N 3.35Å; T135-V138 PolarHBondContact O-N 3.45Å; T135-S139 WeakPolarHBondContact O-CB 3.31Å; T135-S139 PolarHBondContact O-N 3.5Å; T135-M184 VanDerWaalsContact CB-SD 3.59Å; T135-Q187 HydrophobicContact CG2-CG 4Å; T135-F227 HydrophobicContact CG2-CE2 3.81Å; T135-F227 HydrophobicContact CG2-CZ 3.99Å
136	V	98.3	Very high	97.2	Very high	2 Å²	2	22.8 Å²	22.8	1%	0.012	12%	0.119	C	C	.	.	H	α-helix	trans	-59	-47.2	171	168.6	0	0	0	0	110.4	Y132 Q134 V138 S139 V140 W177 M184	Y132-V136 HydrophobicContact CD1-CG2 4.29Å; Y132-V136 HydrophobicContact CD2-CG2 4.09Å; Y132-V136 HydrophobicContact CE1-CG2 3.91Å; Y132-V136 HydrophobicContact CE2-CG2 3.7Å; Y132-V136 HydrophobicContact CG-CG2 4.38Å; Y132-V136 WeakPolarHBondContact O-CB 3.5Å; Y132-V136 VanDerWaalsContact O-CG2 3.24Å; Y132-V136 WeakPolarHBondContact O-CG2 3.44Å; Y132-V136 PolarHBondContact O-N 3.22Å; Q134-V136 PolarHBondContact O-N 3.2Å; V136-V138 PolarHBondContact O-N 3.44Å; V136-S139 WeakPolarHBondContact O-CB 3.23Å; V136-S139 PolarHBondContact O-N 3.06Å; V136-V140 HydrophobicContact CG1-CG2 4.22Å; V136-V140 WeakPolarHBondContact O-CG2 3.47Å; V136-V140 PolarHBondContact O-N 2.91Å; V136-W177 HydrophobicContact CG1-CE3 4.45Å; V136-W177 HydrophobicContact CG1-CZ3 4.26Å; V136-M184 HydrophobicContact CG2-CB 3.7Å; V136-M184 HydrophobicContact CG2-CG 4.05Å
137	S	97.3	Very high	97.2	Very high	2 Å²	2	20.8 Å²	20.8	1%	0.014	11%	0.111	C	C	.	.	H	α-helix	trans	-64.5	-39.5	180	-175.8	0	0	0	0	112.9	A99 V103 L133 Q134 T135 S139 V140 S141	A99-S137 PolarHBondContact O-OG 3.41Å; V103-S137 VanDerWaalsContact CG1-OG 3.29Å; V103-S137 WeakPolarHBondContact CG1-OG 3.47Å; L133-S137 WeakPolarHBondContact O-CB 3.04Å; L133-S137 PolarHBondContact O-N 3.43Å; Q134-S137 PolarHBondContact O-N 3.26Å; T135-S137 VanDerWaalsContact C-N 3.35Å; S137-S139 VanDerWaalsContact C-N 3.32Å; S137-S139 PolarHBondContact O-N 2.76Å; S137-V140 PolarHBondContact O-N 3.16Å; S137-S141 VanDerWaalsContact O-CB 3.31Å; S137-S141 WeakPolarHBondContact O-CB 3.46Å; S137-S141 PolarHBondContact O-N 2.92Å; S137-S141 PolarHBondContact O-OG 3.34Å
138	V	96.1	Very high	97	Very high	15 Å²	15	20.9 Å²	20.9	9%	0.091	11%	0.112	C	C	.	.	H	α-helix	trans	-58.8	-46.2	172.3	176	0	0	0	0	110.7	Q134 T135 V136 S141 V142 Y317	Q134-V138 WeakPolarHBondContact O-CG2 3.25Å; Q134-V138 PolarHBondContact O-N 3.42Å; T135-V138 PolarHBondContact O-N 3.45Å; V136-V138 PolarHBondContact O-N 3.44Å; V138-S141 PolarHBondContact O-N 3.21Å; V138-V142 PolarHBondContact O-N 2.9Å; V138-Y317 HydrophobicContact CB-CE1 4.3Å; V138-Y317 HydrophobicContact CG1-CD1 4.27Å; V138-Y317 HydrophobicContact CG1-CE1 3.75Å; V138-Y317 HydrophobicContact CG2-CE1 3.65Å
139	S	97.6	Very high	96.8	Very high	2 Å²	2	18.1 Å²	18.1	1%	0.014	10%	0.1	C	C	.	.	H	α-helix	trans	-61.9	-46.7	176.6	-178.9	0	0	0	0	112.4	T135 V136 S137 S141 V142 L143 S180	T135-S139 WeakPolarHBondContact O-CB 3.31Å; T135-S139 PolarHBondContact O-N 3.5Å; V136-S139 WeakPolarHBondContact O-CB 3.23Å; V136-S139 PolarHBondContact O-N 3.06Å; S137-S139 VanDerWaalsContact C-N 3.32Å; S137-S139 PolarHBondContact O-N 2.76Å; S139-S141 VanDerWaalsContact C-N 3.26Å; S139-S141 PolarHBondContact O-N 3.29Å; S139-V142 WeakPolarHBondContact O-CG1 3.4Å; S139-V142 PolarHBondContact O-N 3.32Å; S139-L143 WeakPolarHBondContact O-CB 3.38Å; S139-L143 VanDerWaalsContact O-CG 3.27Å; S139-L143 WeakPolarHBondContact O-CG 3.32Å; S139-L143 PolarHBondContact O-N 2.88Å; S139-S180 WeakPolarHBondContact CB-OG 3.26Å; S139-S180 WeakPolarHBondContact OG-CB 3.13Å; S139-S180 PolarHBondContact OG-OG 3.42Å
140	V	98.2	Very high	96.5	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-59.6	-42.1	177	170	0	0	0	0	110.1	A99 V136 S137 T144 I176 W177 S180	A99-V140 HydrophobicContact CB-CB 4.33Å; A99-V140 HydrophobicContact CB-CG1 3.88Å; V136-V140 HydrophobicContact CG1-CG2 4.22Å; V136-V140 WeakPolarHBondContact O-CG2 3.47Å; V136-V140 PolarHBondContact O-N 2.91Å; S137-V140 PolarHBondContact O-N 3.16Å; V140-T144 WeakPolarHBondContact O-CB 3.46Å; V140-T144 PolarHBondContact O-N 3.11Å; V140-T144 PolarHBondContact O-OG1 2.91Å; V140-I176 HydrophobicContact CB-CG2 4.16Å; V140-I176 HydrophobicContact CG1-CG2 3.97Å; V140-I176 HydrophobicContact CG2-CG2 4.12Å; V140-W177 HydrophobicContact CG1-CZ2 4.21Å; V140-W177 HydrophobicContact CG2-CD2 3.97Å; V140-W177 HydrophobicContact CG2-CE3 4.01Å; V140-W177 HydrophobicContact CG2-CG 4.45Å; V140-W177 HydrophobicContact CG2-CZ2 4.48Å; V140-W177 HydrophobicContact CG2-CZ3 4.3Å; V140-S180 PolarHBondContact N-OG 3.43Å
141	S	96.4	Very high	96.1	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-62.8	-51.9	-179.3	-63.5	0	0	0	0	111.8	L96 S137 V138 S139 L143 T144 L145	L96-S141 WeakPolarHBondContact CD1-OG 3.26Å; S137-S141 VanDerWaalsContact O-CB 3.31Å; S137-S141 WeakPolarHBondContact O-CB 3.46Å; S137-S141 PolarHBondContact O-N 2.92Å; S137-S141 PolarHBondContact O-OG 3.34Å; V138-S141 PolarHBondContact O-N 3.21Å; S139-S141 VanDerWaalsContact C-N 3.26Å; S139-S141 PolarHBondContact O-N 3.29Å; S141-L143 PolarHBondContact O-N 2.92Å; S141-T144 PolarHBondContact O-N 3.25Å; S141-L145 WeakPolarHBondContact O-CG 3.38Å; S141-L145 PolarHBondContact O-N 3.5Å
142	V	96.8	Very high	95.8	Very high	0 Å²	0	20.3 Å²	20.3	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-67.4	-38.6	-178.3	72.6	0	0	0	0	112.5	V138 S139 L145 S146 T231 P235 M239 F313	V138-V142 PolarHBondContact O-N 2.9Å; S139-V142 WeakPolarHBondContact O-CG1 3.4Å; S139-V142 PolarHBondContact O-N 3.32Å; V142-L145 PolarHBondContact O-N 3.34Å; V142-S146 WeakPolarHBondContact O-CB 3.43Å; V142-S146 PolarHBondContact O-N 3.49Å; V142-S146 PolarHBondContact O-OG 3.3Å; V142-T231 WeakPolarHBondContact CG2-O 3.45Å; V142-P235 HydrophobicContact CG2-CB 3.37Å; V142-P235 HydrophobicContact CG2-CG 3.76Å; V142-M239 HydrophobicContact CG2-CE 4.1Å; V142-F313 HydrophobicContact CB-CE1 4.39Å; V142-F313 HydrophobicContact CB-CZ 3.9Å; V142-F313 HydrophobicContact CG2-CE1 4.09Å; V142-F313 HydrophobicContact CG2-CZ 4.11Å
143	L	97.2	Very high	95.4	Very high	46 Å²	46	20 Å²	20	24%	0.241	10%	0.103	C	C	.	.	H	α-helix	trans	-69	-35.7	176.2	-68.4	178.4	0	0	0	111.6	S139 S141 S146 C147 I176 V179	S139-L143 WeakPolarHBondContact O-CB 3.38Å; S139-L143 VanDerWaalsContact O-CG 3.27Å; S139-L143 WeakPolarHBondContact O-CG 3.32Å; S139-L143 PolarHBondContact O-N 2.88Å; S141-L143 PolarHBondContact O-N 2.92Å; L143-S146 PolarHBondContact O-N 3.15Å; L143-C147 WeakPolarHBondContact O-CB 3.44Å; L143-C147 PolarHBondContact O-N 3.15Å; L143-C147 PolarHBondContact O-SG 3.23Å; L143-I176 HydrophobicContact CB-CG1 4.05Å; L143-I176 HydrophobicContact CB-CG2 3.92Å; L143-I176 HydrophobicContact CD1-CG2 4.3Å; L143-V179 HydrophobicContact CD1-CG1 4.29Å
144	T	97.1	Very high	95.1	Very high	0 Å²	0	22.6 Å²	22.6	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-64.6	-47.3	173.6	-62.8	0	0	0	0	111.2	F92 N95 L96 V140 S141 S146 C147 I148	F92-T144 HydrophobicContact CB-CG2 3.86Å; F92-T144 HydrophobicContact CD1-CG2 4.2Å; F92-T144 HydrophobicContact CG-CG2 4.46Å; F92-T144 WeakPolarHBondContact O-CG2 3.39Å; N95-T144 HydrophobicContact CB-CG2 4.43Å; N95-T144 PolarHBondContact ND2-OG1 2.85Å; L96-T144 HydrophobicContact CB-CG2 4.23Å; V140-T144 WeakPolarHBondContact O-CB 3.46Å; V140-T144 PolarHBondContact O-N 3.11Å; V140-T144 PolarHBondContact O-OG1 2.91Å; S141-T144 PolarHBondContact O-N 3.25Å; T144-S146 VanDerWaalsContact C-N 3.29Å; T144-S146 PolarHBondContact O-N 3.31Å; T144-C147 PolarHBondContact O-N 3.38Å; T144-I148 HydrophobicContact CG2-CD1 4.15Å; T144-I148 WeakPolarHBondContact O-CG1 3.43Å; T144-I148 PolarHBondContact O-N 2.9Å
145	L	95	Very high	94.5	Very high	13 Å²	13	21.8 Å²	21.8	7%	0.068	11%	0.111	C	C	.	.	H	α-helix	trans	-61.2	-39.5	175.8	-70.2	174.5	0	0	0	111.8	L96 S141 V142 I148 A149 M239 V309 F313	L96-L145 HydrophobicContact CD2-CD2 4.11Å; S141-L145 WeakPolarHBondContact O-CG 3.38Å; S141-L145 PolarHBondContact O-N 3.5Å; V142-L145 PolarHBondContact O-N 3.34Å; L145-I148 HydrophobicContact CD2-CD1 4.46Å; L145-I148 PolarHBondContact O-N 3.43Å; L145-A149 PolarHBondContact O-N 3.03Å; L145-M239 HydrophobicContact CB-CE 4.31Å; L145-M239 HydrophobicContact CB-SD 3.6Å; L145-M239 VanDerWaalsContact CB-SD 3.6Å; L145-V309 HydrophobicContact CD2-CG1 3.73Å; L145-F313 HydrophobicContact CD1-CB 3.96Å; L145-F313 HydrophobicContact CD1-CD1 4.14Å; L145-F313 HydrophobicContact CD1-CD2 3.66Å; L145-F313 HydrophobicContact CD1-CE2 4.19Å; L145-F313 HydrophobicContact CD1-CG 3.64Å
146	S	96.2	Very high	94	Very high	18 Å²	18	21.6 Å²	21.6	13%	0.126	11%	0.11	C	C	.	.	H	α-helix	trans	-62	-44.7	174.3	-60.2	0	0	0	0	111.6	V142 L143 T144 I148 A149 L150 M239	V142-S146 WeakPolarHBondContact O-CB 3.43Å; V142-S146 PolarHBondContact O-N 3.49Å; V142-S146 PolarHBondContact O-OG 3.3Å; L143-S146 PolarHBondContact O-N 3.15Å; T144-S146 VanDerWaalsContact C-N 3.29Å; T144-S146 PolarHBondContact O-N 3.31Å; S146-I148 VanDerWaalsContact C-N 3.34Å; S146-I148 PolarHBondContact O-N 3.32Å; S146-A149 PolarHBondContact O-N 3.23Å; S146-L150 WeakPolarHBondContact O-CB 3.33Å; S146-L150 WeakPolarHBondContact O-CG 3.16Å; S146-L150 PolarHBondContact O-N 2.85Å; S146-M239 PolarHBondContact N-SD 2.91Å
147	C	95.4	Very high	93.4	Very high	31 Å²	31	22.5 Å²	22.5	21%	0.209	12%	0.116	C	C	.	.	H	α-helix	trans	-63.7	-38.2	175.2	-72.1	0	0	0	0	112.6	F92 L143 T144 L150 D151 I176	F92-C147 HydrophobicContact CD1-CB 4.29Å; F92-C147 HydrophobicContact CE1-CB 3.8Å; F92-C147 HydrophobicContact CE2-CB 4.31Å; F92-C147 HydrophobicContact CZ-CB 3.81Å; L143-C147 WeakPolarHBondContact O-CB 3.44Å; L143-C147 PolarHBondContact O-N 3.15Å; L143-C147 PolarHBondContact O-SG 3.23Å; T144-C147 PolarHBondContact O-N 3.38Å; C147-L150 PolarHBondContact O-N 2.98Å; C147-D151 WeakPolarHBondContact O-CB 3.37Å; C147-D151 PolarHBondContact O-N 3.44Å; C147-I176 HydrophobicContact CB-CD1 4.47Å
148	I	93.9	Very high	92.8	Very high	2 Å²	2	26 Å²	26	1%	0.01	13%	0.132	C	C	.	.	H	α-helix	trans	-62.5	-46.6	173.7	-69.4	166.8	0	0	0	110.4	T89 F92 I93 T144 L145 S146 L150 D151 R152 L306	T89-I148 HydrophobicContact CG2-CG2 4.18Å; F92-I148 HydrophobicContact CB-CD1 3.73Å; F92-I148 HydrophobicContact CB-CG1 3.45Å; F92-I148 VanDerWaalsContact CB-CG1 3.45Å; F92-I148 HydrophobicContact CD2-CG1 4.13Å; F92-I148 HydrophobicContact CG-CG1 3.99Å; I93-I148 HydrophobicContact CG1-CD1 4.49Å; T144-I148 HydrophobicContact CG2-CD1 4.15Å; T144-I148 WeakPolarHBondContact O-CG1 3.43Å; T144-I148 PolarHBondContact O-N 2.9Å; L145-I148 HydrophobicContact CD2-CD1 4.46Å; L145-I148 PolarHBondContact O-N 3.43Å; S146-I148 VanDerWaalsContact C-N 3.34Å; S146-I148 PolarHBondContact O-N 3.32Å; I148-L150 PolarHBondContact O-N 2.93Å; I148-D151 PolarHBondContact O-N 3.09Å; I148-R152 HydrophobicContact CG2-CG 4.43Å; I148-R152 WeakPolarHBondContact O-CB 3.28Å; I148-R152 WeakPolarHBondContact O-CG 3.25Å; I148-R152 PolarHBondContact O-N 2.96Å; I148-L306 HydrophobicContact CG2-CD1 3.64Å; I148-L306 HydrophobicContact CG2-CD2 3.76Å; I148-L306 HydrophobicContact CG2-CG 4.23Å
149	A	93.6	Very high	91.9	Very high	2 Å²	2	29 Å²	29	2%	0.017	15%	0.151	C	C	.	.	H	α-helix	trans	-61	-44.6	178.5	0	0	0	0	0	111.4	L145 S146 R152 W153 M239 A242 Y243	L145-A149 PolarHBondContact O-N 3.03Å; S146-A149 PolarHBondContact O-N 3.23Å; A149-R152 PolarHBondContact O-N 3.46Å; A149-W153 VanDerWaalsContact O-CB 3.27Å; A149-W153 WeakPolarHBondContact O-CB 3.47Å; A149-W153 PolarHBondContact O-N 2.87Å; A149-M239 HydrophobicContact CB-CB 4.31Å; A149-M239 HydrophobicContact CB-CG 3.86Å; A149-A242 HydrophobicContact CB-CB 4.47Å; A149-Y243 HydrophobicContact CB-CD2 4.44Å; A149-Y243 HydrophobicContact CB-CE2 3.7Å
150	L	92.1	Very high	90.8	Very high	86 Å²	86	37.1 Å²	37.1	45%	0.45	19%	0.194	S	C	.	.	H	α-helix	trans	-64.5	-46.4	177.1	-72	172.6	0	0	0	112.4	S146 C147 I148 R152 W153 Y154	S146-L150 WeakPolarHBondContact O-CB 3.33Å; S146-L150 WeakPolarHBondContact O-CG 3.16Å; S146-L150 PolarHBondContact O-N 2.85Å; C147-L150 PolarHBondContact O-N 2.98Å; I148-L150 PolarHBondContact O-N 2.93Å; L150-R152 PolarHBondContact O-N 3.08Å; L150-W153 PolarHBondContact O-N 3.38Å; L150-Y154 VanDerWaalsContact O-CD2 3.26Å; L150-Y154 WeakPolarHBondContact O-CD2 3.48Å; L150-Y154 PolarHBondContact O-N 3.02Å
151	D	90.6	Very high	89.4	Confident	7 Å²	7	44.9 Å²	44.9	4%	0.037	23%	0.232	C	C	.	.	H	α-helix	trans	-55.4	-44.1	175.8	176.4	74	0	0	0	111.1	T89 C147 I148 A155 F162 S164	T89-D151 PolarHBondContact OG1-OD2 3.4Å; C147-D151 WeakPolarHBondContact O-CB 3.37Å; C147-D151 PolarHBondContact O-N 3.44Å; I148-D151 PolarHBondContact O-N 3.09Å; D151-A155 VanDerWaalsContact O-CB 3.27Å; D151-A155 WeakPolarHBondContact O-CB 3.24Å; D151-A155 PolarHBondContact O-N 3.28Å; D151-F162 WeakPolarHBondContact OD1-CE1 3.39Å; D151-S164 WeakPolarHBondContact OD1-CB 3.44Å; D151-S164 PolarHBondContact OD1-OG 3.2Å
152	R	89.8	Confident	88.1	Confident	51 Å²	51	47 Å²	47	19%	0.192	24%	0.241	C	C	.	.	H	α-helix	trans	-70.1	-41.1	179.6	-66.4	-74.6	140.6	-146.9	1.5	112	T89 I148 A149 L150 A155 I156 I246 L306	T89-R152 VanDerWaalsContact OG1-CZ 3.24Å; T89-R152 PolarHBondContact OG1-NE 2.93Å; T89-R152 PolarHBondContact OG1-NH2 3.35Å; I148-R152 HydrophobicContact CG2-CG 4.43Å; I148-R152 WeakPolarHBondContact O-CB 3.28Å; I148-R152 WeakPolarHBondContact O-CG 3.25Å; I148-R152 PolarHBondContact O-N 2.96Å; A149-R152 PolarHBondContact O-N 3.46Å; L150-R152 PolarHBondContact O-N 3.08Å; R152-A155 PolarHBondContact O-N 3.44Å; R152-I156 WeakPolarHBondContact O-CB 3.41Å; R152-I156 WeakPolarHBondContact O-CD1 3.31Å; R152-I156 VanDerWaalsContact O-CG1 3.27Å; R152-I156 WeakPolarHBondContact O-CG1 3.35Å; R152-I156 PolarHBondContact O-N 3Å; R152-I246 HydrophobicContact CB-CD1 4.05Å; R152-L306 HydrophobicContact CG-CD1 3.53Å
153	W	91.1	Very high	87.1	Confident	45 Å²	45	55.5 Å²	55.5	17%	0.17	28%	0.278	C	S	.	.	H	α-helix	trans	-61.9	-49.4	177.3	178.6	81.7	0	0	0	111	A149 L150 A155 I156 C157 H158 A242 I246	A149-W153 VanDerWaalsContact O-CB 3.27Å; A149-W153 WeakPolarHBondContact O-CB 3.47Å; A149-W153 PolarHBondContact O-N 2.87Å; L150-W153 PolarHBondContact O-N 3.38Å; W153-A155 PolarHBondContact O-N 3.29Å; W153-I156 PolarHBondContact O-N 3.02Å; W153-C157 VanDerWaalsContact CD1-SG 3.59Å; W153-C157 WeakPolarHBondContact O-CA 3.47Å; W153-C157 WeakPolarHBondContact O-CB 2.94Å; W153-C157 PolarHBondContact O-N 3.09Å; W153-H158 AromaticContact CH2-CD2 3.71Å; W153-H158 AromaticContact CH2-NE2 3.57Å; W153-H158 AromaticContact CZ2-CD2 3.85Å; W153-H158 AromaticContact CZ2-NE2 3.53Å; W153-A242 HydrophobicContact CB-CB 4.23Å; W153-A242 HydrophobicContact CG-CB 4.36Å; W153-I246 HydrophobicContact CB-CD1 4.05Å; W153-I246 HydrophobicContact CB-CG1 4.26Å
154	Y	89.6	Confident	86.3	Confident	92 Å²	92	55.7 Å²	55.7	36%	0.361	28%	0.283	S	S	.	.	H	α-helix	trans	-61.2	-45.1	175.5	-82.2	-67.2	0	0	0	112.4	L150 I156 H158 F162	L150-Y154 VanDerWaalsContact O-CD2 3.26Å; L150-Y154 WeakPolarHBondContact O-CD2 3.48Å; L150-Y154 PolarHBondContact O-N 3.02Å; Y154-I156 VanDerWaalsContact C-N 3.26Å; Y154-I156 PolarHBondContact O-N 3.49Å; Y154-H158 HydrophobicContact CD1-CB 4.37Å; Y154-H158 CarbonylContact O-C 3.06Å; Y154-H158 VanDerWaalsContact O-CA 3.31Å; Y154-H158 WeakPolarHBondContact O-CA 3.41Å; Y154-H158 PolarHBondContact O-N 2.93Å; Y154-H158 VanDerWaalsContact O-O 3.11Å; Y154-F162 HydrophobicContact CD1-CB 4.46Å; Y154-F162 HydrophobicContact CD1-CD2 4.07Å; Y154-F162 HydrophobicContact CD1-CE2 4.44Å; Y154-F162 HydrophobicContact CD1-CG 4.46Å; Y154-F162 HydrophobicContact CD2-CD2 4.08Å; Y154-F162 AromaticContact CD2-CE2 3.62Å; Y154-F162 HydrophobicContact CD2-CE2 3.62Å; Y154-F162 AromaticContact CD2-CZ 3.89Å; Y154-F162 HydrophobicContact CD2-CZ 3.89Å; Y154-F162 HydrophobicContact CE2-CE2 4.28Å; Y154-F162 HydrophobicContact CG-CB 4.43Å; Y154-F162 HydrophobicContact CG-CD1 4.49Å; Y154-F162 AromaticContact CG-CD2 3.7Å; Y154-F162 HydrophobicContact CG-CD2 3.7Å; Y154-F162 HydrophobicContact CG-CE1 4.5Å; Y154-F162 AromaticContact CG-CE2 3.72Å; Y154-F162 HydrophobicContact CG-CE2 3.72Å; Y154-F162 HydrophobicContact CG-CG 4.03Å; Y154-F162 HydrophobicContact CG-CZ 4.07Å
155	A	85.9	Confident	85.9	Confident	28 Å²	28	58.8 Å²	58.8	23%	0.231	30%	0.303	C	S	.	.	H	α-helix	trans	-64.9	-26.5	-178.9	0	0	0	0	0	114.2	D151 R152 W153	D151-A155 VanDerWaalsContact O-CB 3.27Å; D151-A155 WeakPolarHBondContact O-CB 3.24Å; D151-A155 PolarHBondContact O-N 3.28Å; R152-A155 PolarHBondContact O-N 3.44Å; W153-A155 PolarHBondContact O-N 3.29Å
156	I	85.4	Confident	85.6	Confident	12 Å²	12	60.1 Å²	60.1	6%	0.062	32%	0.315	C	S	.	.	H	α-helix	trans	-102.1	-46.1	-175.1	-64.7	165.4	0	0	0	111.7	R152 W153 Y154 I246 K249 L250	R152-I156 WeakPolarHBondContact O-CB 3.41Å; R152-I156 WeakPolarHBondContact O-CD1 3.31Å; R152-I156 VanDerWaalsContact O-CG1 3.27Å; R152-I156 WeakPolarHBondContact O-CG1 3.35Å; R152-I156 PolarHBondContact O-N 3Å; W153-I156 PolarHBondContact O-N 3.02Å; Y154-I156 VanDerWaalsContact C-N 3.26Å; Y154-I156 PolarHBondContact O-N 3.49Å; I156-I246 HydrophobicContact CD1-CG1 4.48Å; I156-I246 HydrophobicContact CD1-CG2 3.8Å; I156-I246 HydrophobicContact CG2-CG2 4.39Å; I156-K249 HydrophobicContact CG2-CG 4.47Å; I156-L250 HydrophobicContact CD1-CD1 4.18Å; I156-L250 HydrophobicContact CG2-CD1 4.26Å; I156-L250 HydrophobicContact CG2-CD2 3.8Å; I156-L250 HydrophobicContact CG2-CG 3.77Å
157	C	86.9	Confident	85.4	Confident	20 Å²	20	66.8 Å²	66.8	14%	0.135	34%	0.342	C	S	.	.	H	α-helix	trans	-82.6	-31.2	-177.3	-61.9	0	0	0	0	112.2	W153 P159	W153-C157 VanDerWaalsContact CD1-SG 3.59Å; W153-C157 WeakPolarHBondContact O-CA 3.47Å; W153-C157 WeakPolarHBondContact O-CB 2.94Å; W153-C157 PolarHBondContact O-N 3.09Å; C157-P159 VanDerWaalsContact C-CD 3.49Å
158	H	84.1	Confident	85.2	Confident	77 Å²	77	69.4 Å²	69.4	36%	0.356	35%	0.347	S	S	.	.			trans	-130.1	59	-176	-61.8	-75.8	0	0	0	113	W153 Y154 L160 M161	W153-H158 AromaticContact CH2-CD2 3.71Å; W153-H158 AromaticContact CH2-NE2 3.57Å; W153-H158 AromaticContact CZ2-CD2 3.85Å; W153-H158 AromaticContact CZ2-NE2 3.53Å; Y154-H158 HydrophobicContact CD1-CB 4.37Å; Y154-H158 CarbonylContact O-C 3.06Å; Y154-H158 VanDerWaalsContact O-CA 3.31Å; Y154-H158 WeakPolarHBondContact O-CA 3.41Å; Y154-H158 PolarHBondContact O-N 2.93Å; Y154-H158 VanDerWaalsContact O-O 3.11Å; H158-L160 PolarHBondContact O-N 3.45Å; H158-M161 HydrophobicContact CB-CB 4.39Å; H158-M161 PolarHBondContact O-N 3.42Å
159	P	76.8	Confident	85.1	Confident	77 Å²	77	69.4 Å²	69.4	50%	0.5	35%	0.348	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.5	-21.1	-169.8	25.1	-35.3	0	0	0	115.3	C157	C157-P159 VanDerWaalsContact C-CD 3.49Å
160	L	73.9	Confident	85.1	Confident	173 Å²	173	77.4 Å²	77.4	91%	0.906	38%	0.377	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.4	-16	-177.7	-63	174.6	0	0	0	113.7	H158	H158-L160 PolarHBondContact O-N 3.45Å
161	M	68.7	Low	85.2	Confident	163 Å²	163	77.3 Å²	77.3	80%	0.803	38%	0.377	S	S	*	.	T	Hydrogen-bonded Turn	trans	-98.2	-13.5	-173	-63.4	-64.7	-78.2	0	0	113.1	H158	H158-M161 HydrophobicContact CB-CB 4.39Å; H158-M161 PolarHBondContact O-N 3.42Å
162	F	71.1	Confident	85.5	Confident	43 Å²	43	78.5 Å²	78.5	19%	0.189	39%	0.386	C	S	.	.			trans	-131.9	112.4	-165.7	-168.1	-102.9	0	0	0	113.2	D151 Y154 R168	D151-F162 WeakPolarHBondContact OD1-CE1 3.39Å; Y154-F162 HydrophobicContact CD1-CB 4.46Å; Y154-F162 HydrophobicContact CD1-CD2 4.07Å; Y154-F162 HydrophobicContact CD1-CE2 4.44Å; Y154-F162 HydrophobicContact CD1-CG 4.46Å; Y154-F162 HydrophobicContact CD2-CD2 4.08Å; Y154-F162 AromaticContact CD2-CE2 3.62Å; Y154-F162 HydrophobicContact CD2-CE2 3.62Å; Y154-F162 AromaticContact CD2-CZ 3.89Å; Y154-F162 HydrophobicContact CD2-CZ 3.89Å; Y154-F162 HydrophobicContact CE2-CE2 4.28Å; Y154-F162 HydrophobicContact CG-CB 4.43Å; Y154-F162 HydrophobicContact CG-CD1 4.49Å; Y154-F162 AromaticContact CG-CD2 3.7Å; Y154-F162 HydrophobicContact CG-CD2 3.7Å; Y154-F162 HydrophobicContact CG-CE1 4.5Å; Y154-F162 AromaticContact CG-CE2 3.72Å; Y154-F162 HydrophobicContact CG-CE2 3.72Å; Y154-F162 HydrophobicContact CG-CG 4.03Å; Y154-F162 HydrophobicContact CG-CZ 4.07Å; F162-R168 VanDerWaalsContact CD2-NH1 3.34Å; F162-R168 VanDerWaalsContact CE2-NH2 3.29Å
163	K	75.5	Confident	85.9	Confident	180 Å²	180	77.6 Å²	77.6	78%	0.783	39%	0.385	S	S	*	.			trans	-94.1	110.5	166.6	-65.1	-176.3	-178.3	178.8	0	108.8	T165 R168	K163-T165 HydrophobicContact CB-CG2 4.4Å; K163-T165 PolarHBondContact O-N 2.95Å; K163-R168 PolarHBondContact O-NH1 3.09Å
164	S	79.4	Confident	86.2	Confident	49 Å²	49	79.2 Å²	79.2	34%	0.343	40%	0.4	S	S	.	.			trans	-77.5	109.1	174.3	-166.7	0	0	0	0	109.9	V88 D151	V88-S164 VanDerWaalsContact CB-OG 3.31Å; V88-S164 WeakPolarHBondContact CB-OG 3.48Å; V88-S164 VanDerWaalsContact CG1-OG 3.23Å; V88-S164 WeakPolarHBondContact CG1-OG 3.36Å; V88-S164 WeakPolarHBondContact CG2-OG 3.49Å; D151-S164 WeakPolarHBondContact OD1-CB 3.44Å; D151-S164 PolarHBondContact OD1-OG 3.2Å
165	T	89.1	Confident	86.6	Confident	66 Å²	66	79.7 Å²	79.7	41%	0.405	41%	0.407	S	S	.	.			trans	-113.3	146.1	-176.3	68.7	0	0	0	0	111.8	K163 K167 R168 A169	K163-T165 HydrophobicContact CB-CG2 4.4Å; K163-T165 PolarHBondContact O-N 2.95Å; T165-K167 VanDerWaalsContact C-N 3.29Å; T165-K167 PolarHBondContact O-N 2.92Å; T165-R168 PolarHBondContact O-N 3.5Å; T165-R168 WeakPolarHBondContact OG1-CB 3.28Å; T165-R168 PolarHBondContact OG1-N 2.9Å; T165-A169 PolarHBondContact O-N 2.88Å
166	A	89	Confident	87.2	Confident	40 Å²	40	78.7 Å²	78.7	33%	0.331	40%	0.398	S	S	.	.	H	α-helix	trans	-62.4	-34.7	177.9	0	0	0	0	0	112.7	Y91 A169 R170	Y91-A166 HydrophobicContact CD2-CB 4.45Å; Y91-A166 HydrophobicContact CE2-CB 3.79Å; A166-A169 PolarHBondContact O-N 3.47Å; A166-R170 WeakPolarHBondContact O-CB 3.38Å; A166-R170 PolarHBondContact O-N 3.37Å
167	K	90.9	Very high	87.8	Confident	158 Å²	158	81.6 Å²	81.6	69%	0.687	41%	0.408	S	S	*	.	H	α-helix	trans	-62	-45.9	175.7	-173	175.4	-177.9	178	0	111	T165 R170 N171	T165-K167 VanDerWaalsContact C-N 3.29Å; T165-K167 PolarHBondContact O-N 2.92Å; K167-R170 PolarHBondContact O-N 3.18Å; K167-N171 VanDerWaalsContact O-CG 3.29Å; K167-N171 PolarHBondContact O-N 2.83Å; K167-N171 PolarHBondContact O-OD1 3.47Å
168	R	91	Very high	88.4	Confident	87 Å²	87	85.1 Å²	85.1	33%	0.328	43%	0.425	S	S	.	.	H	α-helix	trans	-64.5	-43.2	177.2	-167.4	-177.4	66.3	-156	-8.6	111.5	F162 K163 T165 R170 N171 S172	F162-R168 VanDerWaalsContact CD2-NH1 3.34Å; F162-R168 VanDerWaalsContact CE2-NH2 3.29Å; K163-R168 PolarHBondContact O-NH1 3.09Å; T165-R168 PolarHBondContact O-N 3.5Å; T165-R168 WeakPolarHBondContact OG1-CB 3.28Å; T165-R168 PolarHBondContact OG1-N 2.9Å; R168-R170 VanDerWaalsContact C-N 3.34Å; R168-R170 PolarHBondContact O-N 3.07Å; R168-N171 PolarHBondContact O-N 2.86Å; R168-S172 PolarHBondContact O-N 2.81Å; R168-S172 PolarHBondContact O-OG 3.18Å; R168-S172 VanDerWaalsContact O-OG 3.12Å
169	A	92.3	Very high	89.1	Confident	2 Å²	2	84.3 Å²	84.3	2%	0.017	43%	0.425	C	S	.	.	H	α-helix	trans	-57.9	-45.7	176.7	0	0	0	0	0	112.3	V88 F92 T165 A166 S172 I173	V88-A169 HydrophobicContact CB-CB 4.3Å; V88-A169 HydrophobicContact CG1-CB 3.65Å; V88-A169 HydrophobicContact CG2-CB 4.15Å; F92-A169 HydrophobicContact CE2-CB 4.34Å; F92-A169 HydrophobicContact CZ-CB 4.33Å; T165-A169 PolarHBondContact O-N 2.88Å; A166-A169 PolarHBondContact O-N 3.47Å; A169-S172 WeakPolarHBondContact O-CB 3.5Å; A169-S172 PolarHBondContact O-N 2.94Å; A169-I173 WeakPolarHBondContact O-CG1 3.34Å; A169-I173 PolarHBondContact O-N 3.31Å
170	R	93.5	Very high	90.1	Very high	169 Å²	169	80.6 Å²	80.6	64%	0.638	40%	0.401	S	S	*	.	H	α-helix	trans	-61.2	-45.5	176.3	-169.2	-171.1	-50.4	-174.2	2.9	112	A166 K167 R168 S172 I173 V174	A166-R170 WeakPolarHBondContact O-CB 3.38Å; A166-R170 PolarHBondContact O-N 3.37Å; K167-R170 PolarHBondContact O-N 3.18Å; R168-R170 VanDerWaalsContact C-N 3.34Å; R168-R170 PolarHBondContact O-N 3.07Å; R170-S172 VanDerWaalsContact C-N 3.33Å; R170-S172 PolarHBondContact O-N 3.33Å; R170-I173 PolarHBondContact O-N 3.45Å; R170-V174 WeakPolarHBondContact O-CG2 3.32Å; R170-V174 PolarHBondContact O-N 2.81Å; R170-V174 VanDerWaalsContact O-N 3.09Å
171	N	94.7	Very high	91.3	Very high	84 Å²	84	74.3 Å²	74.3	45%	0.449	37%	0.371	S	S	.	.	H	α-helix	trans	-62.4	-41.8	177	-69.1	9.1	0	0	0	111.3	K167 R168 I173 V174 I175	K167-N171 VanDerWaalsContact O-CG 3.29Å; K167-N171 PolarHBondContact O-N 2.83Å; K167-N171 PolarHBondContact O-OD1 3.47Å; R168-N171 PolarHBondContact O-N 2.86Å; N171-I173 VanDerWaalsContact C-N 3.34Å; N171-I173 PolarHBondContact O-N 3.36Å; N171-V174 PolarHBondContact O-N 3.46Å; N171-I175 VanDerWaalsContact O-CG1 3.32Å; N171-I175 WeakPolarHBondContact O-CG1 3.36Å; N171-I175 PolarHBondContact O-N 3.2Å
172	S	96.1	Very high	92.7	Very high	33 Å²	33	71.4 Å²	71.4	23%	0.231	36%	0.358	C	S	.	.	H	α-helix	trans	-60.4	-42.3	174.6	-64.2	0	0	0	0	112	R168 A169 R170 V174 I175 I176	R168-S172 PolarHBondContact O-N 2.81Å; R168-S172 PolarHBondContact O-OG 3.18Å; R168-S172 VanDerWaalsContact O-OG 3.12Å; A169-S172 WeakPolarHBondContact O-CB 3.5Å; A169-S172 PolarHBondContact O-N 2.94Å; R170-S172 VanDerWaalsContact C-N 3.33Å; R170-S172 PolarHBondContact O-N 3.33Å; S172-V174 PolarHBondContact O-N 3.1Å; S172-I175 PolarHBondContact O-N 3.03Å; S172-I176 VanDerWaalsContact O-CG1 3.22Å; S172-I176 WeakPolarHBondContact O-CG1 3.44Å; S172-I176 PolarHBondContact O-N 3.22Å
173	I	98.1	Very high	93.9	Very high	31 Å²	31	72.4 Å²	72.4	16%	0.159	36%	0.364	C	S	.	.	H	α-helix	trans	-59.8	-46.9	176.1	-70.7	164.7	0	0	0	111	F92 N95 A169 R170 N171 I175 I176 W177	F92-I173 HydrophobicContact CD1-CD1 4.35Å; F92-I173 HydrophobicContact CD1-CG1 3.92Å; F92-I173 HydrophobicContact CE1-CG1 3.93Å; N95-I173 HydrophobicContact CB-CD1 4.12Å; N95-I173 HydrophobicContact CB-CG1 4.12Å; N95-I173 HydrophobicContact CB-CG2 4.39Å; N95-I173 VanDerWaalsContact OD1-CG2 3.27Å; N95-I173 WeakPolarHBondContact OD1-CG2 3.26Å; A169-I173 WeakPolarHBondContact O-CG1 3.34Å; A169-I173 PolarHBondContact O-N 3.31Å; R170-I173 PolarHBondContact O-N 3.45Å; N171-I173 VanDerWaalsContact C-N 3.34Å; N171-I173 PolarHBondContact O-N 3.36Å; I173-I175 VanDerWaalsContact C-N 3.32Å; I173-I175 PolarHBondContact O-N 3.3Å; I173-I176 WeakPolarHBondContact O-CB 3.36Å; I173-I176 PolarHBondContact O-N 3.24Å; I173-W177 VanDerWaalsContact O-CD1 3.3Å; I173-W177 PolarHBondContact O-N 3.07Å; I173-W177 VanDerWaalsContact O-N 3.1Å
174	V	98.1	Very high	95	Very high	79 Å²	79	64.1 Å²	64.1	48%	0.479	33%	0.328	S	S	.	.	H	α-helix	trans	-59.8	-43.5	177.6	174.1	0	0	0	0	111.3	R170 N171 S172 I176 W177 I178	R170-V174 WeakPolarHBondContact O-CG2 3.32Å; R170-V174 PolarHBondContact O-N 2.81Å; R170-V174 VanDerWaalsContact O-N 3.09Å; N171-V174 PolarHBondContact O-N 3.46Å; S172-V174 PolarHBondContact O-N 3.1Å; V174-I176 PolarHBondContact O-N 3.2Å; V174-W177 PolarHBondContact O-N 2.99Å; V174-I178 HydrophobicContact CG1-CD1 3.76Å; V174-I178 HydrophobicContact CG1-CG1 4.46Å; V174-I178 WeakPolarHBondContact O-CG1 3.32Å; V174-I178 PolarHBondContact O-N 3Å
175	I	98.1	Very high	95.8	Very high	102 Å²	102	65.7 Å²	65.7	52%	0.523	33%	0.332	S	S	.	.	H	α-helix	trans	-62	-43.3	176.6	-67.6	164.3	0	0	0	111.1	N171 S172 I173 W177 I178 V179	N171-I175 VanDerWaalsContact O-CG1 3.32Å; N171-I175 WeakPolarHBondContact O-CG1 3.36Å; N171-I175 PolarHBondContact O-N 3.2Å; S172-I175 PolarHBondContact O-N 3.03Å; I173-I175 VanDerWaalsContact C-N 3.32Å; I173-I175 PolarHBondContact O-N 3.3Å; I175-W177 PolarHBondContact O-N 3.01Å; I175-I178 PolarHBondContact O-N 3.4Å; I175-V179 HydrophobicContact CG2-CG2 4.05Å; I175-V179 WeakPolarHBondContact O-CB 3.46Å; I175-V179 VanDerWaalsContact O-CG2 3.28Å; I175-V179 WeakPolarHBondContact O-CG2 3.46Å; I175-V179 PolarHBondContact O-N 3.06Å
176	I	98.4	Very high	96.2	Very high	8 Å²	8	65.1 Å²	65.1	4%	0.041	33%	0.33	C	S	.	.	H	α-helix	trans	-55.7	-51.9	177.8	-71.7	164.9	0	0	0	110	F92 V140 L143 C147 S172 I173 V174 I178 V179 S180	F92-I176 HydrophobicContact CE1-CD1 4.32Å; V140-I176 HydrophobicContact CB-CG2 4.16Å; V140-I176 HydrophobicContact CG1-CG2 3.97Å; V140-I176 HydrophobicContact CG2-CG2 4.12Å; L143-I176 HydrophobicContact CB-CG1 4.05Å; L143-I176 HydrophobicContact CB-CG2 3.92Å; L143-I176 HydrophobicContact CD1-CG2 4.3Å; C147-I176 HydrophobicContact CB-CD1 4.47Å; S172-I176 VanDerWaalsContact O-CG1 3.22Å; S172-I176 WeakPolarHBondContact O-CG1 3.44Å; S172-I176 PolarHBondContact O-N 3.22Å; I173-I176 WeakPolarHBondContact O-CB 3.36Å; I173-I176 PolarHBondContact O-N 3.24Å; V174-I176 PolarHBondContact O-N 3.2Å; I176-I178 PolarHBondContact O-N 2.99Å; I176-V179 PolarHBondContact O-N 3.42Å; I176-S180 VanDerWaalsContact O-CB 3.28Å; I176-S180 WeakPolarHBondContact O-CB 3.26Å; I176-S180 PolarHBondContact O-N 3.29Å; I176-S180 PolarHBondContact O-OG 3.01Å
177	W	98.6	Very high	96.5	Very high	73 Å²	73	63.8 Å²	63.8	28%	0.277	32%	0.317	S	S	.	.	H	α-helix	trans	-61.7	-46.5	180	-80.8	95	0	0	0	112.5	N95 L102 V136 V140 I173 V174 I175 V179 S180 C181	N95-W177 PolarHBondContact OD1-NE1 2.79Å; L102-W177 HydrophobicContact CD2-CH2 4.1Å; L102-W177 HydrophobicContact CD2-CZ3 4.35Å; V136-W177 HydrophobicContact CG1-CE3 4.45Å; V136-W177 HydrophobicContact CG1-CZ3 4.26Å; V140-W177 HydrophobicContact CG1-CZ2 4.21Å; V140-W177 HydrophobicContact CG2-CD2 3.97Å; V140-W177 HydrophobicContact CG2-CE3 4.01Å; V140-W177 HydrophobicContact CG2-CG 4.45Å; V140-W177 HydrophobicContact CG2-CZ2 4.48Å; V140-W177 HydrophobicContact CG2-CZ3 4.3Å; I173-W177 VanDerWaalsContact O-CD1 3.3Å; I173-W177 PolarHBondContact O-N 3.07Å; I173-W177 VanDerWaalsContact O-N 3.1Å; V174-W177 PolarHBondContact O-N 2.99Å; I175-W177 PolarHBondContact O-N 3.01Å; W177-V179 PolarHBondContact O-N 3.44Å; W177-S180 PolarHBondContact O-N 3.02Å; W177-C181 VanDerWaalsContact O-CB 3.31Å; W177-C181 WeakPolarHBondContact O-CB 3.26Å; W177-C181 PolarHBondContact O-N 3.49Å; W177-C181 PolarHBondContact O-SG 3.42Å
178	I	98.6	Very high	96.8	Very high	94 Å²	94	57.3 Å²	57.3	48%	0.482	29%	0.293	S	S	.	.	H	α-helix	trans	-59.5	-49.5	178.9	-69.2	170.2	0	0	0	110.5	V174 I175 I176 C181 I182	V174-I178 HydrophobicContact CG1-CD1 3.76Å; V174-I178 HydrophobicContact CG1-CG1 4.46Å; V174-I178 WeakPolarHBondContact O-CG1 3.32Å; V174-I178 PolarHBondContact O-N 3Å; I175-I178 PolarHBondContact O-N 3.4Å; I176-I178 PolarHBondContact O-N 2.99Å; I178-C181 PolarHBondContact O-N 3.28Å; I178-I182 HydrophobicContact CG2-CD1 3.68Å; I178-I182 WeakPolarHBondContact O-CB 3.08Å; I178-I182 WeakPolarHBondContact O-CD1 3.34Å; I178-I182 VanDerWaalsContact O-CG1 3.24Å; I178-I182 WeakPolarHBondContact O-CG1 3.49Å; I178-I182 PolarHBondContact O-N 3.38Å
179	V	98.3	Very high	97.1	Very high	59 Å²	59	58.5 Å²	58.5	36%	0.358	30%	0.304	S	S	.	.	H	α-helix	trans	-61.5	-51.2	179.9	171	0	0	0	0	110.2	L143 I175 I176 W177 C181 I182 I183	L143-V179 HydrophobicContact CD1-CG1 4.29Å; I175-V179 HydrophobicContact CG2-CG2 4.05Å; I175-V179 WeakPolarHBondContact O-CB 3.46Å; I175-V179 VanDerWaalsContact O-CG2 3.28Å; I175-V179 WeakPolarHBondContact O-CG2 3.46Å; I175-V179 PolarHBondContact O-N 3.06Å; I176-V179 PolarHBondContact O-N 3.42Å; W177-V179 PolarHBondContact O-N 3.44Å; V179-C181 PolarHBondContact O-N 3.01Å; V179-I182 PolarHBondContact O-N 3.46Å; V179-I183 HydrophobicContact CG1-CG2 4.19Å; V179-I183 WeakPolarHBondContact O-CG1 3.27Å; V179-I183 WeakPolarHBondContact O-CG2 3.41Å; V179-I183 PolarHBondContact O-N 2.86Å
180	S	98.4	Very high	97.3	Very high	0 Å²	0	59.1 Å²	59.1	0%	0	31%	0.308	C	S	.	.	H	α-helix	trans	-57.5	-45.4	179.6	-66.8	0	0	0	0	112.5	S139 V140 I176 W177 I182 M184	S139-S180 WeakPolarHBondContact CB-OG 3.26Å; S139-S180 WeakPolarHBondContact OG-CB 3.13Å; S139-S180 PolarHBondContact OG-OG 3.42Å; V140-S180 PolarHBondContact N-OG 3.43Å; I176-S180 VanDerWaalsContact O-CB 3.28Å; I176-S180 WeakPolarHBondContact O-CB 3.26Å; I176-S180 PolarHBondContact O-N 3.29Å; I176-S180 PolarHBondContact O-OG 3.01Å; W177-S180 PolarHBondContact O-N 3.02Å; S180-I182 VanDerWaalsContact C-N 3.34Å; S180-I182 PolarHBondContact O-N 3.42Å; S180-M184 WeakPolarHBondContact O-CB 3.45Å; S180-M184 VanDerWaalsContact O-CG 3.24Å; S180-M184 WeakPolarHBondContact O-CG 3.32Å; S180-M184 PolarHBondContact O-N 3Å
181	C	98.4	Very high	97.5	Very high	41 Å²	41	51.6 Å²	51.6	28%	0.277	28%	0.28	S	S	.	.	H	α-helix	trans	-62.4	-40.7	177.7	-71.6	0	0	0	0	112.1	Y132 W177 I178 V179 I185	Y132-C181 VanDerWaalsContact OH-CA 3.32Å; Y132-C181 WeakPolarHBondContact OH-CA 3.47Å; Y132-C181 WeakPolarHBondContact OH-CB 3.48Å; Y132-C181 PolarHBondContact OH-O 3Å; W177-C181 VanDerWaalsContact O-CB 3.31Å; W177-C181 WeakPolarHBondContact O-CB 3.26Å; W177-C181 PolarHBondContact O-N 3.49Å; W177-C181 PolarHBondContact O-SG 3.42Å; I178-C181 PolarHBondContact O-N 3.28Å; V179-C181 PolarHBondContact O-N 3.01Å; C181-I185 WeakPolarHBondContact O-CG1 3.28Å
182	I	98.4	Very high	97.5	Very high	102 Å²	102	50.8 Å²	50.8	52%	0.523	27%	0.274	S	S	.	.	H	α-helix	trans	-70.2	-50.5	-179.2	-70	168.5	0	0	0	111.3	I178 V179 S180 M184 I185	I178-I182 HydrophobicContact CG2-CD1 3.68Å; I178-I182 WeakPolarHBondContact O-CB 3.08Å; I178-I182 WeakPolarHBondContact O-CD1 3.34Å; I178-I182 VanDerWaalsContact O-CG1 3.24Å; I178-I182 WeakPolarHBondContact O-CG1 3.49Å; I178-I182 PolarHBondContact O-N 3.38Å; V179-I182 PolarHBondContact O-N 3.46Å; S180-I182 VanDerWaalsContact C-N 3.34Å; S180-I182 PolarHBondContact O-N 3.42Å; I182-M184 PolarHBondContact O-N 3.04Å; I182-I185 WeakPolarHBondContact O-CB 3.41Å; I182-I185 WeakPolarHBondContact O-CG1 3.44Å; I182-I185 PolarHBondContact O-N 3.46Å
183	I	97	Very high	97.4	Very high	63 Å²	63	50.7 Å²	50.7	32%	0.323	27%	0.272	S	S	.	.	H	α-helix	trans	-67.8	-19.5	-173.8	66.2	173.1	0	0	0	112.9	V179 P186 V230	V179-I183 HydrophobicContact CG1-CG2 4.19Å; V179-I183 WeakPolarHBondContact O-CG1 3.27Å; V179-I183 WeakPolarHBondContact O-CG2 3.41Å; V179-I183 PolarHBondContact O-N 2.86Å; I183-P186 WeakPolarHBondContact O-CD 3.26Å; I183-V230 HydrophobicContact CD1-CG1 4.04Å
184	M	97.6	Very high	97	Very high	6 Å²	6	52.3 Å²	52.3	3%	0.03	29%	0.287	C	S	.	.	T	Hydrogen-bonded Turn	trans	-95.4	-2.1	179.8	-62.6	-60	139	0	0	113.7	Y132 T135 V136 S180 I182 P186 Q187 F227 T231	Y132-M184 HydrophobicContact CD2-CB 4.08Å; Y132-M184 WeakPolarHBondContact CD2-O 3.26Å; Y132-M184 HydrophobicContact CE2-CB 3.88Å; T135-M184 VanDerWaalsContact CB-SD 3.59Å; V136-M184 HydrophobicContact CG2-CB 3.7Å; V136-M184 HydrophobicContact CG2-CG 4.05Å; S180-M184 WeakPolarHBondContact O-CB 3.45Å; S180-M184 VanDerWaalsContact O-CG 3.24Å; S180-M184 WeakPolarHBondContact O-CG 3.32Å; S180-M184 PolarHBondContact O-N 3Å; I182-M184 PolarHBondContact O-N 3.04Å; M184-P186 VanDerWaalsContact C-N 3.3Å; M184-Q187 VanDerWaalsContact O-CB 3.28Å; M184-Q187 WeakPolarHBondContact O-CB 3.23Å; M184-Q187 PolarHBondContact O-N 3.3Å; M184-Q187 VanDerWaalsContact O-N 3.07Å; M184-F227 HydrophobicContact CE-CD2 4.14Å; M184-F227 HydrophobicContact CE-CE2 4Å; M184-F227 HydrophobicContact SD-CD2 4.13Å; M184-F227 HydrophobicContact SD-CE2 3.69Å; M184-T231 HydrophobicContact CE-CG2 3.77Å
185	I	97.7	Very high	96.3	Very high	83 Å²	83	51 Å²	51	43%	0.426	28%	0.281	S	S	.	.	H	α-helix	trans	-52.3	-42.9	175	-67	172.5	0	0	0	112.4	C181 I182 Q187 A188 I189	C181-I185 WeakPolarHBondContact O-CG1 3.28Å; I182-I185 WeakPolarHBondContact O-CB 3.41Å; I182-I185 WeakPolarHBondContact O-CG1 3.44Å; I182-I185 PolarHBondContact O-N 3.46Å; I185-Q187 PolarHBondContact O-N 2.94Å; I185-A188 WeakPolarHBondContact O-CB 3.45Å; I185-A188 PolarHBondContact O-N 3.43Å; I185-I189 HydrophobicContact CG2-CD1 3.85Å; I185-I189 HydrophobicContact CG2-CG1 4.28Å; I185-I189 PolarHBondContact O-N 3.28Å
186	P	96.6	Very high	95.2	Very high	54 Å²	54	51 Å²	51	35%	0.351	28%	0.28	S	S	.	.	H	α-helix	trans	-56.9	-35.9	178.9	-26	36	0	0	0	113.1	I183 M184 A188 I189 V190 Y223	I183-P186 WeakPolarHBondContact O-CD 3.26Å; M184-P186 VanDerWaalsContact C-N 3.3Å; P186-A188 VanDerWaalsContact C-N 3.34Å; P186-A188 PolarHBondContact O-N 3.45Å; P186-I189 PolarHBondContact O-N 2.92Å; P186-V190 WeakPolarHBondContact O-CG2 3.17Å; P186-V190 PolarHBondContact O-N 3.49Å; P186-V190 VanDerWaalsContact O-N 3.1Å; P186-Y223 HydrophobicContact CB-CD2 4.42Å; P186-Y223 HydrophobicContact CB-CE2 3.94Å
187	Q	96.1	Very high	93.9	Very high	12 Å²	12	56.4 Å²	56.4	6%	0.056	30%	0.304	C	S	.	.	H	α-helix	trans	-56.1	-49.7	174.6	-167.7	70.7	42.7	0	0	110.6	T135 M184 I185 I189 V190 M191 E212 Y223	T135-Q187 HydrophobicContact CG2-CG 4Å; M184-Q187 VanDerWaalsContact O-CB 3.28Å; M184-Q187 WeakPolarHBondContact O-CB 3.23Å; M184-Q187 PolarHBondContact O-N 3.3Å; M184-Q187 VanDerWaalsContact O-N 3.07Å; I185-Q187 PolarHBondContact O-N 2.94Å; Q187-I189 VanDerWaalsContact C-N 3.25Å; Q187-I189 PolarHBondContact O-N 3.34Å; Q187-V190 WeakPolarHBondContact O-CG2 3.32Å; Q187-V190 PolarHBondContact O-N 3.26Å; Q187-M191 PolarHBondContact NE2-SD 3.41Å; Q187-M191 VanDerWaalsContact NE2-SD 3.36Å; Q187-M191 VanDerWaalsContact O-CG 3.3Å; Q187-M191 WeakPolarHBondContact O-CG 3.47Å; Q187-M191 PolarHBondContact O-N 2.88Å; Q187-E212 PolarHBondContact NE2-OE1 3.27Å; Q187-Y223 WeakPolarHBondContact CB-OH 3.36Å; Q187-Y223 VanDerWaalsContact OE1-CE1 3.24Å; Q187-Y223 PolarHBondContact OE1-OH 3.4Å
188	A	97	Very high	92.3	Very high	22 Å²	22	57.5 Å²	57.5	18%	0.182	32%	0.32	C	S	.	.	H	α-helix	trans	-62.8	-33.4	-178.9	0	0	0	0	0	112.6	K128 Y132 I185 P186	K128-A188 WeakPolarHBondContact CD-O 3.38Å; K128-A188 VanDerWaalsContact CG-O 3.31Å; K128-A188 WeakPolarHBondContact CG-O 3.4Å; K128-A188 PolarHBondContact NZ-O 3.42Å; K128-A188 VanDerWaalsContact NZ-O 3.12Å; Y132-A188 HydrophobicContact CD2-CB 3.88Å; Y132-A188 HydrophobicContact CG-CB 4.09Å; I185-A188 WeakPolarHBondContact O-CB 3.45Å; I185-A188 PolarHBondContact O-N 3.43Å; P186-A188 VanDerWaalsContact C-N 3.34Å; P186-A188 PolarHBondContact O-N 3.45Å
189	I	97.1	Very high	90.6	Very high	112 Å²	112	56.2 Å²	56.2	57%	0.574	33%	0.33	S	S	*	.	H	α-helix	trans	-67.8	-48.1	179.3	-65.3	173	0	0	0	110.1	K128 I185 P186 Q187	K128-I189 PolarHBondContact NZ-O 3.26Å; I185-I189 HydrophobicContact CG2-CD1 3.85Å; I185-I189 HydrophobicContact CG2-CG1 4.28Å; I185-I189 PolarHBondContact O-N 3.28Å; P186-I189 PolarHBondContact O-N 2.92Å; Q187-I189 VanDerWaalsContact C-N 3.25Å; Q187-I189 PolarHBondContact O-N 3.34Å
190	V	96.9	Very high	88.9	Confident	15 Å²	15	55.7 Å²	55.7	9%	0.091	33%	0.325	C	S	.	.	H	α-helix	trans	-77.7	-21	-172.8	-59.1	0	0	0	0	114.4	P186 Q187 E192 E212 R213 W214	P186-V190 WeakPolarHBondContact O-CG2 3.17Å; P186-V190 PolarHBondContact O-N 3.49Å; P186-V190 VanDerWaalsContact O-N 3.1Å; Q187-V190 WeakPolarHBondContact O-CG2 3.32Å; Q187-V190 PolarHBondContact O-N 3.26Å; V190-E192 PolarHBondContact O-N 3.25Å; V190-E212 HydrophobicContact CG2-CB 4.14Å; V190-E212 HydrophobicContact CG2-CG 4.05Å; V190-E212 CarbonylContact O-C 3.59Å; V190-E212 WeakPolarHBondContact O-CA 3.43Å; V190-R213 PolarHBondContact O-N 3.26Å; V190-W214 HydrophobicContact CB-CZ2 4.26Å; V190-W214 HydrophobicContact CG1-CD2 4.15Å; V190-W214 HydrophobicContact CG1-CE3 3.95Å; V190-W214 HydrophobicContact CG1-CH2 3.75Å; V190-W214 HydrophobicContact CG1-CZ2 3.94Å; V190-W214 HydrophobicContact CG1-CZ3 3.76Å; V190-W214 HydrophobicContact CG2-CH2 4.37Å; V190-W214 HydrophobicContact CG2-CZ2 3.89Å
191	M	97.2	Very high	87.2	Confident	11 Å²	11	57.6 Å²	57.6	5%	0.054	34%	0.341	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-66.6	123	177.1	-65.7	-46.7	-66.5	0	0	111.2	C127 K128 P131 Q187 C210 E212	C127-M191 VanDerWaalsContact O-CB 3.27Å; C127-M191 WeakPolarHBondContact O-CB 3.4Å; K128-M191 HydrophobicContact CG-CB 4.3Å; K128-M191 WeakPolarHBondContact CG-O 3.43Å; K128-M191 PolarHBondContact NZ-O 2.89Å; P131-M191 HydrophobicContact CB-CE 4.24Å; P131-M191 HydrophobicContact CB-CG 3.9Å; P131-M191 HydrophobicContact CB-SD 4.17Å; P131-M191 HydrophobicContact CG-CE 3.85Å; P131-M191 HydrophobicContact CG-CG 4.04Å; P131-M191 HydrophobicContact CG-SD 4.37Å; Q187-M191 PolarHBondContact NE2-SD 3.41Å; Q187-M191 VanDerWaalsContact NE2-SD 3.36Å; Q187-M191 VanDerWaalsContact O-CG 3.3Å; Q187-M191 WeakPolarHBondContact O-CG 3.47Å; Q187-M191 PolarHBondContact O-N 2.88Å; M191-C210 VanDerWaalsContact CE-SG 3.52Å; M191-E212 HydrophobicContact SD-CG 3.6Å
192	E	95.6	Very high	85.6	Confident	66 Å²	66	63 Å²	63	31%	0.308	37%	0.367	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.8	148	174.3	-68.4	-167.1	177.2	0	0	111.8	C127 V190 D211 R213	C127-E192 VanDerWaalsContact SG-C 3.59Å; V190-E192 PolarHBondContact O-N 3.25Å; E192-D211 PolarHBondContact N-O 2.66Å; E192-D211 PolarHBondContact O-N 3.06Å; E192-D211 VanDerWaalsContact O-N 3.09Å; E192-D211 VanDerWaalsContact O-O 3.13Å; E192-R213 HydrophobicContact CB-CB 4.3Å; E192-R213 HydrophobicContact CG-CB 4.26Å; E192-R213 WeakPolarHBondContact OE2-CD 3.44Å; E192-R213 IonicContact OE2-CZ 3.34Å; E192-R213 IonicContact OE2-NE 3.69Å; E192-R213 IonicContact OE2-NH1 2.77Å; E192-R213 PolarHBondContact OE2-NH1 3.44Å
193	C	93.6	Very high	84	Confident	31 Å²	31	65 Å²	65	21%	0.209	37%	0.372	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.9	134.4	167.1	-66.4	0	0	0	0	110.1	W120 Q124 C127 T208 V209	W120-C193 VanDerWaalsContact CD1-SG 3.54Å; Q124-C193 PolarHBondContact OE1-SG 3.48Å; C127-C193 WeakPolarHBondContact CB-SG 3.27Å; C127-C193 VanDerWaalsContact SG-SG 3.62Å; C193-T208 HydrophobicContact CB-CG2 4.08Å; C193-V209 CarbonylContact C-O 3.56Å; C193-V209 VanDerWaalsContact CA-O 3.25Å; C193-V209 WeakPolarHBondContact CA-O 3.39Å
194	S	88.5	Confident	82.6	Confident	66 Å²	66	62.9 Å²	62.9	46%	0.462	36%	0.362	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.7	145.2	169.7	60.2	0	0	0	0	110.1	V209	S194-V209 PolarHBondContact N-O 2.83Å; S194-V209 WeakPolarHBondContact O-CG2 3.1Å; S194-V209 PolarHBondContact O-N 2.85Å; S194-V209 VanDerWaalsContact OG-CG2 3.31Å; S194-V209 WeakPolarHBondContact OG-CG2 3.42Å
195	S	84.9	Confident	81.2	Confident	50 Å²	50	67.1 Å²	67.1	35%	0.35	39%	0.388	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.5	126.5	174	56.2	0	0	0	0	109.5	F197	S195-F197 VanDerWaalsContact C-N 3.29Å; S195-F197 PolarHBondContact O-N 2.91Å
196	M	73.6	Confident	80.1	Confident	104 Å²	104	63.9 Å²	63.9	51%	0.512	37%	0.372	S	S	.	.	S	Bend	trans	-66.2	-29.8	176.7	-84.1	-158.6	-82.1	0	0	113.1	F207 V209	M196-F207 HydrophobicContact CB-CB 4.49Å; M196-F207 PolarHBondContact N-O 3.35Å; M196-V209 HydrophobicContact CE-CG1 4.19Å
197	F	72.3	Confident	79.3	Confident	121 Å²	121	62.4 Å²	62.4	53%	0.531	36%	0.36	S	S	.	.			trans	-124.3	95.8	-179.4	-65.3	-78.1	0	0	0	111.3	S195 G199 L200 A201 F207	S195-F197 VanDerWaalsContact C-N 3.29Å; S195-F197 PolarHBondContact O-N 2.91Å; F197-G199 PolarHBondContact O-N 3.39Å; F197-L200 HydrophobicContact CB-CB 4.11Å; F197-L200 PolarHBondContact O-N 2.78Å; F197-A201 PolarHBondContact O-N 2.98Å; F197-F207 HydrophobicContact CD2-CB 4.38Å; F197-F207 HydrophobicContact CD2-CD2 4.42Å; F197-F207 HydrophobicContact CD2-CG 4.36Å
198	P	64.6	Low	78.9	Confident	96 Å²	96	63.1 Å²	63.1	62%	0.623	37%	0.365	S	S	*	.	H	α-helix	trans	-57.8	-33.1	-177.2	-24.1	32.4	0	0	0	113.8	L200 A201	P198-L200 VanDerWaalsContact C-N 3.32Å; P198-L200 PolarHBondContact O-N 2.87Å; P198-A201 PolarHBondContact O-N 3.48Å
199	G	63.1	Low	78.6	Confident	67 Å²	67	64 Å²	64	69%	0.691	37%	0.368	S	S	*	.	H	α-helix	trans	-69.1	-26.3	177.9	0	0	0	0	0	114.1	F197	F197-G199 PolarHBondContact O-N 3.39Å
200	L	62.9	Low	78.5	Confident	47 Å²	47	60 Å²	60	25%	0.246	35%	0.349	C	S	.	.	H	α-helix	trans	-92.9	-21.9	176.7	-131.3	73.5	0	0	0	112.4	F39 F197 P198 N202 K203 T204 F207	F39-L200 HydrophobicContact CE1-CD1 4.4Å; F39-L200 HydrophobicContact CZ-CD1 4.46Å; F197-L200 HydrophobicContact CB-CB 4.11Å; F197-L200 PolarHBondContact O-N 2.78Å; P198-L200 VanDerWaalsContact C-N 3.32Å; P198-L200 PolarHBondContact O-N 2.87Å; L200-N202 PolarHBondContact O-N 2.89Å; L200-K203 PolarHBondContact O-N 3.02Å; L200-T204 PolarHBondContact O-N 2.92Å; L200-F207 HydrophobicContact CD2-CD2 4.15Å; L200-F207 HydrophobicContact CD2-CE2 3.9Å
201	A	62	Low	78.4	Confident	41 Å²	41	62 Å²	62	34%	0.339	36%	0.36	S	S	.	.	H	α-helix	trans	-61	-28	-179.4	0	0	0	0	0	113.7	F197 P198 K203	F197-A201 PolarHBondContact O-N 2.98Å; P198-A201 PolarHBondContact O-N 3.48Å; A201-K203 VanDerWaalsContact C-N 3.26Å; A201-K203 PolarHBondContact O-N 3.1Å
202	N	65.4	Low	78.3	Confident	154 Å²	154	62.7 Å²	62.7	82%	0.824	36%	0.363	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.6	-17	174.7	-72.6	-16.1	0	0	0	113.1	L200	L200-N202 PolarHBondContact O-N 2.89Å
203	K	64.2	Low	78.2	Confident	143 Å²	143	67.8 Å²	67.8	62%	0.622	38%	0.38	S	S	*	.	T	Hydrogen-bonded Turn	trans	-110	-32.9	-175.8	-70.8	-164.2	164.8	-151.1	0	113.3	D36 L200 A201	D36-K203 IonicContact OD1-NZ 2.81Å; D36-K203 PolarHBondContact OD1-NZ 3.05Å; L200-K203 PolarHBondContact O-N 3.02Å; A201-K203 VanDerWaalsContact C-N 3.26Å; A201-K203 PolarHBondContact O-N 3.1Å
204	T	68.6	Low	78.3	Confident	20 Å²	20	69.2 Å²	69.2	12%	0.123	38%	0.381	C	S	.	.			trans	-143.5	153.7	-177.2	77.6	0	0	0	0	111.9	L40 L200 L206	L40-T204 HydrophobicContact CD2-CG2 3.64Å; L200-T204 PolarHBondContact O-N 2.92Å; T204-L206 PolarHBondContact O-N 2.98Å; T204-L206 WeakPolarHBondContact OG1-CB 3.46Å; T204-L206 PolarHBondContact OG1-N 3.47Å
205	T	68.2	Low	78.4	Confident	94 Å²	94	69.7 Å²	69.7	58%	0.577	40%	0.396	S	S	*	.	S	Bend	trans	-82.2	0.9	170.2	57.3	0	0	0	0	112.7	T208	T205-T208 WeakPolarHBondContact O-CB 3.47Å; T205-T208 PolarHBondContact O-N 2.64Å; T205-T208 PolarHBondContact O-OG1 2.91Å
206	L	74.6	Confident	78.8	Confident	16 Å²	16	69.1 Å²	69.1	8%	0.084	40%	0.398	C	S	.	.	T	Hydrogen-bonded Turn	trans	-67.2	147.4	-177.7	-164.1	65	0	0	0	110.1	L43 L48 T204 T208	L43-L206 HydrophobicContact CB-CD2 3.97Å; L43-L206 HydrophobicContact CD1-CD2 3.91Å; L43-L206 HydrophobicContact CD2-CD2 3.91Å; L43-L206 HydrophobicContact CG-CD2 4.17Å; L48-L206 HydrophobicContact CD1-CD1 3.53Å; T204-L206 PolarHBondContact O-N 2.98Å; T204-L206 WeakPolarHBondContact OG1-CB 3.46Å; T204-L206 PolarHBondContact OG1-N 3.47Å; L206-T208 PolarHBondContact O-N 3.44Å
207	F	79.3	Confident	79.6	Confident	22 Å²	22	71.5 Å²	71.5	10%	0.096	41%	0.408	C	S	.	.	T	Hydrogen-bonded Turn	trans	63	17.4	-177.4	-41.5	-75.3	0	0	0	115.2	L43 Y47 T119 M196 F197 L200	L43-F207 HydrophobicContact CD2-CE2 4.38Å; L43-F207 HydrophobicContact CD2-CZ 4.19Å; Y47-F207 AromaticContact CD1-CE1 3.84Å; Y47-F207 HydrophobicContact CD1-CE1 3.84Å; Y47-F207 HydrophobicContact CD1-CZ 4.29Å; Y47-F207 HydrophobicContact CE1-CD1 4.16Å; Y47-F207 AromaticContact CE1-CE1 3.39Å; Y47-F207 HydrophobicContact CE1-CE1 3.39Å; Y47-F207 HydrophobicContact CE1-CZ 4.25Å; Y47-F207 HydrophobicContact CE2-CE1 4.15Å; Y47-F207 HydrophobicContact CG-CE1 4.39Å; Y47-F207 AromaticContact CZ-CE1 3.55Å; T119-F207 PolarHBondContact OG1-N 3.01Å; M196-F207 HydrophobicContact CB-CB 4.49Å; M196-F207 PolarHBondContact N-O 3.35Å; F197-F207 HydrophobicContact CD2-CB 4.38Å; F197-F207 HydrophobicContact CD2-CD2 4.42Å; F197-F207 HydrophobicContact CD2-CG 4.36Å; L200-F207 HydrophobicContact CD2-CD2 4.15Å; L200-F207 HydrophobicContact CD2-CE2 3.9Å
208	T	87.8	Confident	80.6	Confident	28 Å²	28	71.4 Å²	71.4	17%	0.172	41%	0.411	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-74.3	127.1	164.1	-56.1	0	0	0	0	108.1	T119 W120 C193 T205 L206	T119-T208 CarbonylContact C-O 3.59Å; W120-T208 WeakPolarHBondContact CB-O 3.26Å; W120-T208 PolarHBondContact N-O 3.17Å; C193-T208 HydrophobicContact CB-CG2 4.08Å; T205-T208 WeakPolarHBondContact O-CB 3.47Å; T205-T208 PolarHBondContact O-N 2.64Å; T205-T208 PolarHBondContact O-OG1 2.91Å; L206-T208 PolarHBondContact O-N 3.44Å
209	V	91.1	Very high	82.1	Confident	39 Å²	39	73.4 Å²	73.4	24%	0.236	41%	0.408	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112	147.4	175.9	-62.4	0	0	0	0	109.9	C193 S194 M196	C193-V209 CarbonylContact C-O 3.56Å; C193-V209 VanDerWaalsContact CA-O 3.25Å; C193-V209 WeakPolarHBondContact CA-O 3.39Å; S194-V209 PolarHBondContact N-O 2.83Å; S194-V209 WeakPolarHBondContact O-CG2 3.1Å; S194-V209 PolarHBondContact O-N 2.85Å; S194-V209 VanDerWaalsContact OG-CG2 3.31Å; S194-V209 WeakPolarHBondContact OG-CG2 3.42Å; M196-V209 HydrophobicContact CE-CG1 4.19Å
210	C	95.1	Very high	83.6	Confident	28 Å²	28	71.1 Å²	71.1	19%	0.189	38%	0.381	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.1	106.4	170.6	175.3	0	0	0	0	107.9	W120 C127 M191	W120-C210 HydrophobicContact CB-CB 3.93Å; W120-C210 HydrophobicContact CD2-CB 3.55Å; W120-C210 HydrophobicContact CE3-CB 3.8Å; W120-C210 HydrophobicContact CG-CB 3.58Å; C127-C210 WeakPolarHBondContact CA-SG 3.41Å; C127-C210 HydrophobicContact CB-CB 3.89Å; C127-C210 WeakPolarHBondContact CB-SG 3.36Å; C127-C210 PolarHBondContact O-SG 2.95Å; C127-C210 VanDerWaalsContact SG-CA 3.58Å; C127-C210 WeakPolarHBondContact SG-CB 3.49Å; C127-C210 CovalentContact SG-SG 2.03Å; C127-C210 PolarHBondContact SG-SG 3.48Å; M191-C210 VanDerWaalsContact CE-SG 3.52Å
211	D	94.1	Very high	85.1	Confident	59 Å²	59	73 Å²	73	32%	0.316	39%	0.387	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-139.5	166.9	-178	-158.6	9.6	0	0	0	111.5	E192 R328	E192-D211 PolarHBondContact N-O 2.66Å; E192-D211 PolarHBondContact O-N 3.06Å; E192-D211 VanDerWaalsContact O-N 3.09Å; E192-D211 VanDerWaalsContact O-O 3.13Å; D211-R328 IonicContact OD1-CZ 2.66Å; D211-R328 IonicContact OD1-NH1 3.68Å; D211-R328 PolarHBondContact OD1-NH1 2.84Å; D211-R328 IonicContact OD1-NH2 3.48Å; D211-R328 PolarHBondContact OD1-NH2 2.86Å; D211-R328 IonicContact OD2-NH1 3.49Å; D211-R328 PolarHBondContact OD2-NH1 2.93Å; D211-R328 IonicContact OD2-NH2 3.45Å
212	E	94.4	Very high	86.7	Confident	25 Å²	25	76.6 Å²	76.6	12%	0.117	40%	0.398	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-75.3	123.3	178.6	-57.8	174.5	-178.4	0	0	111.3	Q187 V190 M191 W214 H224 R328	Q187-E212 PolarHBondContact NE2-OE1 3.27Å; V190-E212 HydrophobicContact CG2-CB 4.14Å; V190-E212 HydrophobicContact CG2-CG 4.05Å; V190-E212 CarbonylContact O-C 3.59Å; V190-E212 WeakPolarHBondContact O-CA 3.43Å; M191-E212 HydrophobicContact SD-CG 3.6Å; E212-W214 PolarHBondContact OE2-NE1 3.39Å; E212-H224 IonicContact OE1-CE1 3.86Å; E212-H224 PolarHBondContact OE1-CE1 3.43Å; E212-H224 IonicContact OE1-NE2 3.78Å; E212-H224 PolarHBondContact OE1-NE2 3.06Å; E212-H224 IonicContact OE2-CD2 3.68Å; E212-H224 IonicContact OE2-CE1 3.2Å; E212-H224 IonicContact OE2-NE2 3.64Å; E212-H224 PolarHBondContact OE2-NE2 3.22Å; E212-R328 IonicContact OE2-NE 3.93Å
213	R	94.5	Very high	88.2	Confident	173 Å²	173	70.8 Å²	70.8	65%	0.653	37%	0.365	S	S	*	.			trans	-102.9	118.3	172.9	-167	-178.2	-177.1	-173.1	-0.2	110.7	V190 E192	V190-R213 PolarHBondContact O-N 3.26Å; E192-R213 HydrophobicContact CB-CB 4.3Å; E192-R213 HydrophobicContact CG-CB 4.26Å; E192-R213 WeakPolarHBondContact OE2-CD 3.44Å; E192-R213 IonicContact OE2-CZ 3.34Å; E192-R213 IonicContact OE2-NE 3.69Å; E192-R213 IonicContact OE2-NH1 2.77Å; E192-R213 PolarHBondContact OE2-NH1 3.44Å
214	W	94.5	Very high	89.7	Confident	61 Å²	61	64.4 Å²	64.4	23%	0.231	34%	0.337	C	S	.	.			trans	-115.1	138.1	-178.4	-65.7	93.7	0	0	0	111.7	V190 E212 G216 Y219 P220 Y223	V190-W214 HydrophobicContact CB-CZ2 4.26Å; V190-W214 HydrophobicContact CG1-CD2 4.15Å; V190-W214 HydrophobicContact CG1-CE3 3.95Å; V190-W214 HydrophobicContact CG1-CH2 3.75Å; V190-W214 HydrophobicContact CG1-CZ2 3.94Å; V190-W214 HydrophobicContact CG1-CZ3 3.76Å; V190-W214 HydrophobicContact CG2-CH2 4.37Å; V190-W214 HydrophobicContact CG2-CZ2 3.89Å; E212-W214 PolarHBondContact OE2-NE1 3.39Å; W214-G216 PolarHBondContact O-N 3.2Å; W214-Y219 HydrophobicContact CE3-CG 4.5Å; W214-P220 HydrophobicContact CB-CG 4.17Å; W214-P220 HydrophobicContact CD2-CB 4.02Å; W214-P220 HydrophobicContact CD2-CG 4.42Å; W214-P220 HydrophobicContact CG-CB 3.85Å; W214-P220 HydrophobicContact CG-CG 3.97Å; W214-Y223 VanDerWaalsContact CH2-CB 3.4Å; W214-Y223 AromaticContact CH2-CD1 3.77Å; W214-Y223 HydrophobicContact CH2-CD1 3.77Å; W214-Y223 AromaticContact CH2-CD2 3.94Å; W214-Y223 HydrophobicContact CH2-CD2 3.94Å; W214-Y223 AromaticContact CH2-CG 3.41Å; W214-Y223 HydrophobicContact CH2-CG 3.41Å; W214-Y223 VanDerWaalsContact CH2-CG 3.41Å; W214-Y223 AromaticContact CZ2-CD1 3.56Å; W214-Y223 HydrophobicContact CZ2-CD1 3.56Å; W214-Y223 HydrophobicContact CZ2-CE1 4.26Å; W214-Y223 AromaticContact CZ2-CG 3.73Å; W214-Y223 HydrophobicContact CZ2-CG 3.73Å
215	G	91.9	Very high	91	Very high	76 Å²	76	67 Å²	67	78%	0.784	35%	0.349	S	S	*	.	S	Bend	trans	-79.1	42.5	176.8	0	0	0	0	0	114.1	Y219	G215-Y219 WeakPolarHBondContact O-CE2 3.48Å
216	G	92.4	Very high	92.4	Very high	38 Å²	38	66 Å²	66	39%	0.392	35%	0.345	S	S	.	.	S	Bend	trans	140.5	163.2	-177.7	0	0	0	0	0	113	W214 I218 P220	W214-G216 PolarHBondContact O-N 3.2Å; G216-I218 PolarHBondContact O-N 3.27Å; G216-P220 WeakPolarHBondContact O-CD 3.11Å
217	E	90.6	Very high	93.4	Very high	153 Å²	153	66.9 Å²	66.9	72%	0.715	35%	0.348	S	S	*	.	S	Bend	trans	-78.1	-18.4	-173.2	-61.4	-174.9	-178	0	0	114.6	P220 K221	E217-P220 WeakPolarHBondContact O-CG 3.45Å; E217-K221 WeakPolarHBondContact O-CG 3.41Å
218	I	94.3	Very high	94.2	Very high	119 Å²	119	67.9 Å²	67.9	61%	0.61	35%	0.353	S	S	*	.	H	α-helix	trans	-79.5	-42.1	-173.9	-60	169.5	0	0	0	111.1	G216 K221 M222	G216-I218 PolarHBondContact O-N 3.27Å; I218-K221 PolarHBondContact O-N 3.46Å; I218-M222 HydrophobicContact CG2-CG 4.16Å; I218-M222 HydrophobicContact CG2-SD 3.89Å; I218-M222 PolarHBondContact O-N 3.32Å
219	Y	94.9	Very high	94.6	Very high	139 Å²	139	70.4 Å²	70.4	55%	0.545	37%	0.365	S	S	.	.	H	α-helix	trans	-57.6	-47.6	-177.6	-57.3	-62.3	0	0	0	114.6	W214 G215 K221 M222 Y223	W214-Y219 HydrophobicContact CE3-CG 4.5Å; G215-Y219 WeakPolarHBondContact O-CE2 3.48Å; Y219-K221 VanDerWaalsContact C-N 3.3Å; Y219-K221 PolarHBondContact O-N 2.88Å; Y219-M222 PolarHBondContact O-N 3.32Å; Y219-Y223 VanDerWaalsContact O-CB 3.29Å; Y219-Y223 WeakPolarHBondContact O-CB 3.36Å; Y219-Y223 PolarHBondContact O-N 3.44Å
220	P	94.5	Very high	94.8	Very high	19 Å²	19	72.2 Å²	72.2	12%	0.123	38%	0.376	C	S	.	.	H	α-helix	trans	-61.7	-39.7	177.2	20.4	-30.2	0	0	0	111.5	W214 G216 E217 Y223 H224	W214-P220 HydrophobicContact CB-CG 4.17Å; W214-P220 HydrophobicContact CD2-CB 4.02Å; W214-P220 HydrophobicContact CD2-CG 4.42Å; W214-P220 HydrophobicContact CG-CB 3.85Å; W214-P220 HydrophobicContact CG-CG 3.97Å; G216-P220 WeakPolarHBondContact O-CD 3.11Å; E217-P220 WeakPolarHBondContact O-CG 3.45Å; P220-Y223 PolarHBondContact O-N 2.65Å; P220-H224 WeakPolarHBondContact O-CB 3.49Å; P220-H224 PolarHBondContact O-CD2 2.8Å; P220-H224 PolarHBondContact O-N 3.19Å
221	K	95.1	Very high	94.8	Very high	86 Å²	86	71.1 Å²	71.1	37%	0.374	37%	0.368	S	S	.	.	H	α-helix	trans	-62.1	-50.3	178.9	-59.3	-176.2	-179.6	-176	0	110.9	E217 I218 Y219 I225 V329	E217-K221 WeakPolarHBondContact O-CG 3.41Å; I218-K221 PolarHBondContact O-N 3.46Å; Y219-K221 VanDerWaalsContact C-N 3.3Å; Y219-K221 PolarHBondContact O-N 2.88Å; K221-I225 WeakPolarHBondContact O-CB 3.32Å; K221-I225 WeakPolarHBondContact O-CD1 3.29Å; K221-I225 WeakPolarHBondContact O-CG1 3.25Å; K221-I225 PolarHBondContact O-N 2.85Å; K221-V329 WeakPolarHBondContact CE-O 3.34Å
222	M	95.4	Very high	94.8	Very high	116 Å²	116	69 Å²	69	57%	0.571	36%	0.356	S	S	*	.	H	α-helix	trans	-60.9	-47.2	178	-72.1	-174.6	64.2	0	0	111.8	I218 Y219 I225 C226	I218-M222 HydrophobicContact CG2-CG 4.16Å; I218-M222 HydrophobicContact CG2-SD 3.89Å; I218-M222 PolarHBondContact O-N 3.32Å; Y219-M222 PolarHBondContact O-N 3.32Å; M222-I225 PolarHBondContact O-N 2.98Å; M222-C226 WeakPolarHBondContact O-CB 3.36Å; M222-C226 PolarHBondContact O-N 3.31Å; M222-C226 PolarHBondContact O-SG 3.37Å; M222-C226 VanDerWaalsContact O-SG 3.36Å
223	Y	96.3	Very high	94.8	Very high	33 Å²	33	71.2 Å²	71.2	13%	0.129	37%	0.367	C	S	.	.	H	α-helix	trans	-60.8	-49.3	-179.3	176.8	-100.8	0	0	0	111.9	P186 Q187 W214 Y219 P220 I225 C226 F227	P186-Y223 HydrophobicContact CB-CD2 4.42Å; P186-Y223 HydrophobicContact CB-CE2 3.94Å; Q187-Y223 WeakPolarHBondContact CB-OH 3.36Å; Q187-Y223 VanDerWaalsContact OE1-CE1 3.24Å; Q187-Y223 PolarHBondContact OE1-OH 3.4Å; W214-Y223 VanDerWaalsContact CH2-CB 3.4Å; W214-Y223 AromaticContact CH2-CD1 3.77Å; W214-Y223 HydrophobicContact CH2-CD1 3.77Å; W214-Y223 AromaticContact CH2-CD2 3.94Å; W214-Y223 HydrophobicContact CH2-CD2 3.94Å; W214-Y223 AromaticContact CH2-CG 3.41Å; W214-Y223 HydrophobicContact CH2-CG 3.41Å; W214-Y223 VanDerWaalsContact CH2-CG 3.41Å; W214-Y223 AromaticContact CZ2-CD1 3.56Å; W214-Y223 HydrophobicContact CZ2-CD1 3.56Å; W214-Y223 HydrophobicContact CZ2-CE1 4.26Å; W214-Y223 AromaticContact CZ2-CG 3.73Å; W214-Y223 HydrophobicContact CZ2-CG 3.73Å; Y219-Y223 VanDerWaalsContact O-CB 3.29Å; Y219-Y223 WeakPolarHBondContact O-CB 3.36Å; Y219-Y223 PolarHBondContact O-N 3.44Å; P220-Y223 PolarHBondContact O-N 2.65Å; Y223-I225 PolarHBondContact O-N 3.46Å; Y223-C226 PolarHBondContact O-N 2.99Å; Y223-F227 VanDerWaalsContact O-CB 3.31Å; Y223-F227 WeakPolarHBondContact O-CB 3.28Å; Y223-F227 PolarHBondContact O-N 3.12Å
224	H	95.8	Very high	94.9	Very high	8 Å²	8	65.3 Å²	65.3	4%	0.037	36%	0.356	C	S	.	.	H	α-helix	trans	-69.5	-31.2	-178.4	-79.2	-77.2	0	0	0	113.1	E212 P220 F228 R328 V329	E212-H224 IonicContact OE1-CE1 3.86Å; E212-H224 PolarHBondContact OE1-CE1 3.43Å; E212-H224 IonicContact OE1-NE2 3.78Å; E212-H224 PolarHBondContact OE1-NE2 3.06Å; E212-H224 IonicContact OE2-CD2 3.68Å; E212-H224 IonicContact OE2-CE1 3.2Å; E212-H224 IonicContact OE2-NE2 3.64Å; E212-H224 PolarHBondContact OE2-NE2 3.22Å; P220-H224 WeakPolarHBondContact O-CB 3.49Å; P220-H224 PolarHBondContact O-CD2 2.8Å; P220-H224 PolarHBondContact O-N 3.19Å; H224-F228 VanDerWaalsContact O-CB 3.3Å; H224-F228 WeakPolarHBondContact O-CB 3.41Å; H224-F228 PolarHBondContact O-N 3.06Å; H224-R328 HydrophobicContact CB-CB 3.96Å; H224-R328 WeakPolarHBondContact CD2-CB 3.23Å; H224-V329 HydrophobicContact CB-CG2 4.07Å
225	I	96.6	Very high	94.9	Very high	75 Å²	75	63 Å²	63	39%	0.385	35%	0.348	S	S	.	.	H	α-helix	trans	-62.8	-51.3	169	-70.2	166.3	0	0	0	110.2	K221 M222 Y223 F227 F228 L229 V329	K221-I225 WeakPolarHBondContact O-CB 3.32Å; K221-I225 WeakPolarHBondContact O-CD1 3.29Å; K221-I225 WeakPolarHBondContact O-CG1 3.25Å; K221-I225 PolarHBondContact O-N 2.85Å; M222-I225 PolarHBondContact O-N 2.98Å; Y223-I225 PolarHBondContact O-N 3.46Å; I225-F227 VanDerWaalsContact C-N 3.33Å; I225-F227 PolarHBondContact O-N 3.06Å; I225-F228 PolarHBondContact O-N 3.17Å; I225-L229 HydrophobicContact CG2-CD1 3.92Å; I225-L229 HydrophobicContact CG2-CG 4.43Å; I225-L229 WeakPolarHBondContact O-CB 3.45Å; I225-L229 VanDerWaalsContact O-CG 3.28Å; I225-L229 WeakPolarHBondContact O-CG 3.3Å; I225-L229 PolarHBondContact O-N 2.89Å; I225-V329 HydrophobicContact CD1-CG1 3.89Å; I225-V329 HydrophobicContact CG1-CG1 4Å; I225-V329 HydrophobicContact CG1-CG2 3.82Å
226	C	96.4	Very high	95.1	Very high	72 Å²	72	60.5 Å²	60.5	49%	0.486	32%	0.317	S	S	.	.	H	α-helix	trans	-61	-43	178.7	-71.8	0	0	0	0	111.6	M222 Y223 L229 V230	M222-C226 WeakPolarHBondContact O-CB 3.36Å; M222-C226 PolarHBondContact O-N 3.31Å; M222-C226 PolarHBondContact O-SG 3.37Å; M222-C226 VanDerWaalsContact O-SG 3.36Å; Y223-C226 PolarHBondContact O-N 2.99Å; C226-L229 PolarHBondContact O-N 3.3Å; C226-V230 VanDerWaalsContact O-CB 3.32Å; C226-V230 WeakPolarHBondContact O-CB 3.31Å; C226-V230 VanDerWaalsContact O-CG2 3.26Å; C226-V230 WeakPolarHBondContact O-CG2 3.46Å; C226-V230 PolarHBondContact O-N 3.14Å
227	F	95.8	Very high	95.2	Very high	35 Å²	35	61.6 Å²	61.6	15%	0.154	32%	0.318	C	S	.	.	H	α-helix	trans	-58.6	-50.7	176.9	-174.9	-86.3	0	0	0	110.8	T135 M184 Y223 I225 L229 V230 T231	T135-F227 HydrophobicContact CG2-CE2 3.81Å; T135-F227 HydrophobicContact CG2-CZ 3.99Å; M184-F227 HydrophobicContact CE-CD2 4.14Å; M184-F227 HydrophobicContact CE-CE2 4Å; M184-F227 HydrophobicContact SD-CD2 4.13Å; M184-F227 HydrophobicContact SD-CE2 3.69Å; Y223-F227 VanDerWaalsContact O-CB 3.31Å; Y223-F227 WeakPolarHBondContact O-CB 3.28Å; Y223-F227 PolarHBondContact O-N 3.12Å; I225-F227 VanDerWaalsContact C-N 3.33Å; I225-F227 PolarHBondContact O-N 3.06Å; F227-L229 VanDerWaalsContact C-N 3.35Å; F227-L229 PolarHBondContact O-N 3.49Å; F227-V230 PolarHBondContact O-N 3.4Å; F227-T231 HydrophobicContact CD1-CG2 4.39Å; F227-T231 WeakPolarHBondContact CD1-OG1 3.35Å; F227-T231 HydrophobicContact CD2-CG2 4.09Å; F227-T231 HydrophobicContact CE1-CG2 4.19Å; F227-T231 VanDerWaalsContact CE1-OG1 3.3Å; F227-T231 WeakPolarHBondContact CE1-OG1 3.45Å; F227-T231 HydrophobicContact CE2-CG2 3.89Å; F227-T231 HydrophobicContact CG-CG2 4.33Å; F227-T231 HydrophobicContact CZ-CG2 3.94Å; F227-T231 WeakPolarHBondContact O-CB 3.37Å; F227-T231 WeakPolarHBondContact O-CG2 3.47Å; F227-T231 PolarHBondContact O-N 2.89Å; F227-T231 PolarHBondContact O-OG1 2.72Å
228	F	96.6	Very high	95.4	Very high	44 Å²	44	60 Å²	60	19%	0.193	31%	0.313	C	S	.	.	H	α-helix	trans	-59.6	-42.8	177.5	174.9	-110.5	0	0	0	112.7	H224 I225 Y232 M233 V325	H224-F228 VanDerWaalsContact O-CB 3.3Å; H224-F228 WeakPolarHBondContact O-CB 3.41Å; H224-F228 PolarHBondContact O-N 3.06Å; I225-F228 PolarHBondContact O-N 3.17Å; F228-Y232 HydrophobicContact CD2-CD1 4.19Å; F228-Y232 AromaticContact CE2-CD1 3.51Å; F228-Y232 HydrophobicContact CE2-CD1 3.51Å; F228-Y232 HydrophobicContact CE2-CE1 4.19Å; F228-Y232 HydrophobicContact CE2-CG 4.27Å; F228-Y232 HydrophobicContact CZ-CD1 4.09Å; F228-Y232 WeakPolarHBondContact O-CB 3.42Å; F228-Y232 PolarHBondContact O-N 3.12Å; F228-Y232 VanDerWaalsContact O-N 3.14Å; F228-M233 HydrophobicContact CD1-CB 4.4Å; F228-M233 HydrophobicContact CE1-CB 4.03Å; F228-M233 HydrophobicContact CE1-CE 3.69Å; F228-M233 HydrophobicContact CE1-CG 4.5Å; F228-M233 HydrophobicContact CZ-CB 4.33Å; F228-M233 HydrophobicContact CZ-CE 3.51Å; F228-M233 PolarHBondContact O-N 3.3Å; F228-V325 HydrophobicContact CB-CG2 3.96Å; F228-V325 HydrophobicContact CD1-CG2 4.37Å; F228-V325 HydrophobicContact CD2-CG2 4.12Å; F228-V325 HydrophobicContact CG-CG2 3.9Å
229	L	96.6	Very high	95.4	Very high	81 Å²	81	54.4 Å²	54.4	42%	0.424	29%	0.285	S	S	.	.	I	π-helix	trans	-65.3	-45.1	178.3	-70.4	175.3	0	0	0	112	I225 C226 F227 M233 A234 P235	I225-L229 HydrophobicContact CG2-CD1 3.92Å; I225-L229 HydrophobicContact CG2-CG 4.43Å; I225-L229 WeakPolarHBondContact O-CB 3.45Å; I225-L229 VanDerWaalsContact O-CG 3.28Å; I225-L229 WeakPolarHBondContact O-CG 3.3Å; I225-L229 PolarHBondContact O-N 2.89Å; C226-L229 PolarHBondContact O-N 3.3Å; F227-L229 VanDerWaalsContact C-N 3.35Å; F227-L229 PolarHBondContact O-N 3.49Å; L229-M233 HydrophobicContact CD2-CB 4.21Å; L229-M233 HydrophobicContact CD2-CG 4.34Å; L229-A234 VanDerWaalsContact O-CB 3.26Å; L229-A234 WeakPolarHBondContact O-CB 3.48Å; L229-A234 PolarHBondContact O-N 2.9Å; L229-P235 WeakPolarHBondContact O-CD 3.29Å
230	V	95.2	Very high	95.4	Very high	76 Å²	76	50.8 Å²	50.8	46%	0.461	28%	0.277	S	S	.	.	I	π-helix	trans	-77.8	-39.9	-174.2	171	0	0	0	0	112.4	I183 C226 F227 P235	I183-V230 HydrophobicContact CD1-CG1 4.04Å; C226-V230 VanDerWaalsContact O-CB 3.32Å; C226-V230 WeakPolarHBondContact O-CB 3.31Å; C226-V230 VanDerWaalsContact O-CG2 3.26Å; C226-V230 WeakPolarHBondContact O-CG2 3.46Å; C226-V230 PolarHBondContact O-N 3.14Å; F227-V230 PolarHBondContact O-N 3.4Å; V230-P235 WeakPolarHBondContact O-CD 3.39Å; V230-P235 WeakPolarHBondContact O-CG 3.41Å
231	T	93.9	Very high	95.4	Very high	5 Å²	5	54.5 Å²	54.5	3%	0.031	30%	0.295	C	S	.	.	I	π-helix	trans	-94.4	-14.9	-173	67.7	0	0	0	0	113.7	V142 M184 F227	V142-T231 WeakPolarHBondContact CG2-O 3.45Å; M184-T231 HydrophobicContact CE-CG2 3.77Å; F227-T231 HydrophobicContact CD1-CG2 4.39Å; F227-T231 WeakPolarHBondContact CD1-OG1 3.35Å; F227-T231 HydrophobicContact CD2-CG2 4.09Å; F227-T231 HydrophobicContact CE1-CG2 4.19Å; F227-T231 VanDerWaalsContact CE1-OG1 3.3Å; F227-T231 WeakPolarHBondContact CE1-OG1 3.45Å; F227-T231 HydrophobicContact CE2-CG2 3.89Å; F227-T231 HydrophobicContact CG-CG2 4.33Å; F227-T231 HydrophobicContact CZ-CG2 3.94Å; F227-T231 WeakPolarHBondContact O-CB 3.37Å; F227-T231 WeakPolarHBondContact O-CG2 3.47Å; F227-T231 PolarHBondContact O-N 2.89Å; F227-T231 PolarHBondContact O-OG1 2.72Å
232	Y	94.8	Very high	95.4	Very high	14 Å²	14	50.8 Å²	50.8	6%	0.055	28%	0.281	C	S	.	.	I	π-helix	trans	-132.8	-69.8	-176.6	-171.1	-99.9	0	0	0	112.8	F228 L236 A314 L318	F228-Y232 HydrophobicContact CD2-CD1 4.19Å; F228-Y232 AromaticContact CE2-CD1 3.51Å; F228-Y232 HydrophobicContact CE2-CD1 3.51Å; F228-Y232 HydrophobicContact CE2-CE1 4.19Å; F228-Y232 HydrophobicContact CE2-CG 4.27Å; F228-Y232 HydrophobicContact CZ-CD1 4.09Å; F228-Y232 WeakPolarHBondContact O-CB 3.42Å; F228-Y232 PolarHBondContact O-N 3.12Å; F228-Y232 VanDerWaalsContact O-N 3.14Å; Y232-L236 HydrophobicContact CE1-CD2 3.94Å; Y232-L236 HydrophobicContact CE2-CD2 4.33Å; Y232-L236 WeakPolarHBondContact O-CB 3.3Å; Y232-L236 PolarHBondContact O-N 3.21Å; Y232-A314 PolarHBondContact OH-O 3.26Å; Y232-A314 VanDerWaalsContact OH-O 3.04Å; Y232-L318 HydrophobicContact CE1-CD1 4.2Å; Y232-L318 WeakPolarHBondContact OH-CD1 3.47Å
233	M	95.4	Very high	95.2	Very high	72 Å²	72	46 Å²	46	36%	0.355	26%	0.256	S	S	.	.	I	π-helix	trans	-66.3	-54.3	-164	-175.5	62.3	72.3	0	0	113.9	F228 L229 L236 C237	F228-M233 HydrophobicContact CD1-CB 4.4Å; F228-M233 HydrophobicContact CE1-CB 4.03Å; F228-M233 HydrophobicContact CE1-CE 3.69Å; F228-M233 HydrophobicContact CE1-CG 4.5Å; F228-M233 HydrophobicContact CZ-CB 4.33Å; F228-M233 HydrophobicContact CZ-CE 3.51Å; F228-M233 PolarHBondContact O-N 3.3Å; L229-M233 HydrophobicContact CD2-CB 4.21Å; L229-M233 HydrophobicContact CD2-CG 4.34Å; M233-L236 PolarHBondContact O-N 3.32Å; M233-C237 WeakPolarHBondContact O-CB 3.45Å; M233-C237 PolarHBondContact O-N 2.99Å; M233-C237 PolarHBondContact O-SG 3.47Å
234	A	95.4	Very high	95	Very high	50 Å²	50	48.7 Å²	48.7	41%	0.413	27%	0.272	S	S	.	.	H	α-helix	trans	-66.1	-47	-175.6	0	0	0	0	0	112.4	L229 L236 C237 L238	L229-A234 VanDerWaalsContact O-CB 3.26Å; L229-A234 WeakPolarHBondContact O-CB 3.48Å; L229-A234 PolarHBondContact O-N 2.9Å; A234-L236 PolarHBondContact O-N 3.1Å; A234-C237 PolarHBondContact O-N 3.15Å; A234-L238 VanDerWaalsContact O-CG 3.32Å; A234-L238 WeakPolarHBondContact O-CG 3.44Å; A234-L238 PolarHBondContact O-N 3.02Å
235	P	95.4	Very high	94.8	Very high	11 Å²	11	52.8 Å²	52.8	7%	0.071	29%	0.292	C	S	.	.	H	α-helix	trans	-61.5	-41.8	174.6	-22.7	33.2	0	0	0	113.2	V142 L229 V230 C237 L238 M239	V142-P235 HydrophobicContact CG2-CB 3.37Å; V142-P235 HydrophobicContact CG2-CG 3.76Å; L229-P235 WeakPolarHBondContact O-CD 3.29Å; V230-P235 WeakPolarHBondContact O-CD 3.39Å; V230-P235 WeakPolarHBondContact O-CG 3.41Å; P235-C237 PolarHBondContact O-N 3.4Å; P235-L238 PolarHBondContact O-N 3.42Å; P235-M239 HydrophobicContact CB-CE 4.19Å; P235-M239 WeakPolarHBondContact O-CB 3.05Å; P235-M239 VanDerWaalsContact O-CG 3.27Å; P235-M239 WeakPolarHBondContact O-CG 3.4Å; P235-M239 PolarHBondContact O-N 2.91Å
236	L	95.4	Very high	94.5	Very high	24 Å²	24	49.3 Å²	49.3	13%	0.126	27%	0.274	C	S	.	.	H	α-helix	trans	-60.5	-47.5	178.7	-178.7	61.8	0	0	0	111.1	Y232 M233 A234 L238 M239 V240 L310 A314	Y232-L236 HydrophobicContact CE1-CD2 3.94Å; Y232-L236 HydrophobicContact CE2-CD2 4.33Å; Y232-L236 WeakPolarHBondContact O-CB 3.3Å; Y232-L236 PolarHBondContact O-N 3.21Å; M233-L236 PolarHBondContact O-N 3.32Å; A234-L236 PolarHBondContact O-N 3.1Å; L236-L238 PolarHBondContact O-N 2.65Å; L236-M239 PolarHBondContact O-N 3.48Å; L236-V240 HydrophobicContact CD1-CG2 4.22Å; L236-V240 HydrophobicContact CG-CG2 4.46Å; L236-V240 WeakPolarHBondContact O-CB 3.48Å; L236-V240 VanDerWaalsContact O-CG2 3.25Å; L236-V240 WeakPolarHBondContact O-CG2 3.31Å; L236-V240 PolarHBondContact O-N 2.98Å; L236-L310 HydrophobicContact CD1-CD1 3.78Å; L236-L310 HydrophobicContact CD1-CG 4.29Å; L236-A314 HydrophobicContact CD1-CB 3.86Å; L236-A314 HydrophobicContact CD2-CB 4.13Å
237	C	95.4	Very high	94.1	Very high	61 Å²	61	50 Å²	50	41%	0.412	27%	0.269	S	S	.	.	H	α-helix	trans	-57.5	-47.8	175.3	-74.3	0	0	0	0	111.8	M233 A234 P235 M239 V240 L241	M233-C237 WeakPolarHBondContact O-CB 3.45Å; M233-C237 PolarHBondContact O-N 2.99Å; M233-C237 PolarHBondContact O-SG 3.47Å; A234-C237 PolarHBondContact O-N 3.15Å; P235-C237 PolarHBondContact O-N 3.4Å; C237-M239 PolarHBondContact O-N 3.2Å; C237-V240 PolarHBondContact O-N 3.3Å; C237-L241 WeakPolarHBondContact O-CB 3.49Å; C237-L241 VanDerWaalsContact O-CG 3.26Å; C237-L241 WeakPolarHBondContact O-CG 3.4Å; C237-L241 PolarHBondContact O-N 3.18Å
238	L	94.5	Very high	93.7	Very high	119 Å²	119	56.5 Å²	56.5	62%	0.623	29%	0.292	S	S	*	.	H	α-helix	trans	-61.4	-43.7	178.3	-69.8	174.6	0	0	0	112.2	A234 P235 L236 L241 A242	A234-L238 VanDerWaalsContact O-CG 3.32Å; A234-L238 WeakPolarHBondContact O-CG 3.44Å; A234-L238 PolarHBondContact O-N 3.02Å; P235-L238 PolarHBondContact O-N 3.42Å; L236-L238 PolarHBondContact O-N 2.65Å; L238-L241 PolarHBondContact O-N 3.41Å; L238-A242 WeakPolarHBondContact O-CB 3.49Å; L238-A242 PolarHBondContact O-N 2.98Å
239	M	94.9	Very high	93.2	Very high	3 Å²	3	57.1 Å²	57.1	2%	0.015	30%	0.295	C	S	.	.	H	α-helix	trans	-64.2	-45	177.1	-72.2	-171.3	-77.5	0	0	111.5	V142 L145 S146 A149 P235 L236 C237 L241 A242 Y243 L310	V142-M239 HydrophobicContact CG2-CE 4.1Å; L145-M239 HydrophobicContact CB-CE 4.31Å; L145-M239 HydrophobicContact CB-SD 3.6Å; L145-M239 VanDerWaalsContact CB-SD 3.6Å; S146-M239 PolarHBondContact N-SD 2.91Å; A149-M239 HydrophobicContact CB-CB 4.31Å; A149-M239 HydrophobicContact CB-CG 3.86Å; P235-M239 HydrophobicContact CB-CE 4.19Å; P235-M239 WeakPolarHBondContact O-CB 3.05Å; P235-M239 VanDerWaalsContact O-CG 3.27Å; P235-M239 WeakPolarHBondContact O-CG 3.4Å; P235-M239 PolarHBondContact O-N 2.91Å; L236-M239 PolarHBondContact O-N 3.48Å; C237-M239 PolarHBondContact O-N 3.2Å; M239-L241 PolarHBondContact O-N 3.41Å; M239-A242 PolarHBondContact O-N 3.05Å; M239-Y243 WeakPolarHBondContact O-CD2 3.25Å; M239-Y243 PolarHBondContact O-N 3.14Å; M239-L310 HydrophobicContact CB-CD1 3.98Å; M239-L310 HydrophobicContact CB-CD2 3.8Å; M239-L310 HydrophobicContact CE-CD1 3.51Å; M239-L310 HydrophobicContact CG-CD1 4.46Å; M239-L310 HydrophobicContact SD-CD1 3.63Å
240	V	94.8	Very high	92.5	Very high	63 Å²	63	53.4 Å²	53.4	38%	0.382	28%	0.276	S	S	.	.	H	α-helix	trans	-59.3	-47.5	176.4	168.8	0	0	0	0	110.4	L236 C237 A242 Y243 L244 L310	L236-V240 HydrophobicContact CD1-CG2 4.22Å; L236-V240 HydrophobicContact CG-CG2 4.46Å; L236-V240 WeakPolarHBondContact O-CB 3.48Å; L236-V240 VanDerWaalsContact O-CG2 3.25Å; L236-V240 WeakPolarHBondContact O-CG2 3.31Å; L236-V240 PolarHBondContact O-N 2.98Å; C237-V240 PolarHBondContact O-N 3.3Å; V240-A242 VanDerWaalsContact C-N 3.34Å; V240-A242 PolarHBondContact O-N 2.95Å; V240-Y243 PolarHBondContact O-N 2.76Å; V240-L244 HydrophobicContact CG1-CD1 3.83Å; V240-L244 HydrophobicContact CG1-CG 4.2Å; V240-L244 WeakPolarHBondContact O-CB 3.46Å; V240-L244 VanDerWaalsContact O-CG 3.23Å; V240-L244 WeakPolarHBondContact O-CG 3.48Å; V240-L244 PolarHBondContact O-N 3.41Å; V240-L310 HydrophobicContact CG2-CD2 4.35Å
241	L	94.8	Very high	91.8	Very high	97 Å²	97	54.6 Å²	54.6	51%	0.508	27%	0.272	S	S	.	.	H	α-helix	trans	-59.5	-44.1	176.5	-69.2	175.5	0	0	0	112	C237 L238 M239 L244 Q245	C237-L241 WeakPolarHBondContact O-CB 3.49Å; C237-L241 VanDerWaalsContact O-CG 3.26Å; C237-L241 WeakPolarHBondContact O-CG 3.4Å; C237-L241 PolarHBondContact O-N 3.18Å; L238-L241 PolarHBondContact O-N 3.41Å; M239-L241 PolarHBondContact O-N 3.41Å; L241-L244 PolarHBondContact O-N 3.43Å; L241-Q245 WeakPolarHBondContact O-CG 3.28Å; L241-Q245 PolarHBondContact O-N 2.95Å
242	A	93.8	Very high	90.9	Very high	8 Å²	8	58.7 Å²	58.7	7%	0.066	30%	0.3	C	S	.	.	H	α-helix	trans	-60.7	-46.8	176.4	0	0	0	0	0	111.7	A149 W153 L238 M239 V240 Q245 I246	A149-A242 HydrophobicContact CB-CB 4.47Å; W153-A242 HydrophobicContact CB-CB 4.23Å; W153-A242 HydrophobicContact CG-CB 4.36Å; L238-A242 WeakPolarHBondContact O-CB 3.49Å; L238-A242 PolarHBondContact O-N 2.98Å; M239-A242 PolarHBondContact O-N 3.05Å; V240-A242 VanDerWaalsContact C-N 3.34Å; V240-A242 PolarHBondContact O-N 2.95Å; A242-Q245 PolarHBondContact O-N 3.34Å; A242-I246 VanDerWaalsContact O-CG1 3.26Å; A242-I246 WeakPolarHBondContact O-CG1 3.3Å; A242-I246 PolarHBondContact O-N 3.43Å
243	Y	91.6	Very high	89.2	Confident	15 Å²	15	66.5 Å²	66.5	6%	0.059	33%	0.329	C	S	.	.	H	α-helix	trans	-69.7	-34.3	179.1	-77.6	-65.2	0	0	0	113.3	A149 M239 V240 Q245 I246 F247 L306 L310	A149-Y243 HydrophobicContact CB-CD2 4.44Å; A149-Y243 HydrophobicContact CB-CE2 3.7Å; M239-Y243 WeakPolarHBondContact O-CD2 3.25Å; M239-Y243 PolarHBondContact O-N 3.14Å; V240-Y243 PolarHBondContact O-N 2.76Å; Y243-Q245 VanDerWaalsContact C-N 3.33Å; Y243-I246 HydrophobicContact CD1-CD1 3.9Å; Y243-I246 HydrophobicContact CE1-CD1 4.15Å; Y243-I246 PolarHBondContact O-N 2.89Å; Y243-F247 VanDerWaalsContact O-CB 3.26Å; Y243-F247 WeakPolarHBondContact O-CB 3.41Å; Y243-F247 PolarHBondContact O-N 2.85Å; Y243-L306 HydrophobicContact CE1-CB 4.07Å; Y243-L306 VanDerWaalsContact OH-CB 3.26Å; Y243-L306 WeakPolarHBondContact OH-CB 3.42Å; Y243-L310 HydrophobicContact CD2-CD2 3.52Å; Y243-L310 HydrophobicContact CE2-CB 4.5Å; Y243-L310 HydrophobicContact CE2-CD2 3.81Å
244	L	91.5	Very high	87.2	Confident	89 Å²	89	68.9 Å²	68.9	47%	0.466	34%	0.34	S	S	.	.	H	α-helix	trans	-62	-42.8	172.2	-73.5	173.7	0	0	0	111	V240 L241 F247 R248	V240-L244 HydrophobicContact CG1-CD1 3.83Å; V240-L244 HydrophobicContact CG1-CG 4.2Å; V240-L244 WeakPolarHBondContact O-CB 3.46Å; V240-L244 VanDerWaalsContact O-CG 3.23Å; V240-L244 WeakPolarHBondContact O-CG 3.48Å; V240-L244 PolarHBondContact O-N 3.41Å; L241-L244 PolarHBondContact O-N 3.43Å; L244-F247 PolarHBondContact O-N 3.34Å; L244-R248 WeakPolarHBondContact O-CB 3.14Å; L244-R248 VanDerWaalsContact O-CG 3.28Å; L244-R248 WeakPolarHBondContact O-CG 3.3Å; L244-R248 PolarHBondContact O-N 3.43Å
245	Q	92.1	Very high	85.2	Confident	94 Å²	94	68.9 Å²	68.9	44%	0.439	33%	0.332	S	S	.	.	H	α-helix	trans	-66	-43.1	175.1	-69	179.7	42.5	0	0	112.1	L241 A242 Y243 F247 R248 K249	L241-Q245 WeakPolarHBondContact O-CG 3.28Å; L241-Q245 PolarHBondContact O-N 2.95Å; A242-Q245 PolarHBondContact O-N 3.34Å; Y243-Q245 VanDerWaalsContact C-N 3.33Å; Q245-F247 VanDerWaalsContact C-N 3.32Å; Q245-F247 PolarHBondContact O-N 3.46Å; Q245-R248 PolarHBondContact O-N 2.77Å; Q245-K249 WeakPolarHBondContact O-CB 3.38Å; Q245-K249 PolarHBondContact O-N 3.23Å
246	I	90.3	Very high	82.6	Confident	2 Å²	2	73.7 Å²	73.7	1%	0.01	36%	0.363	C	S	.	.	H	α-helix	trans	-57.9	-46.5	173.7	-70.8	164.8	0	0	0	110.3	R152 W153 I156 A242 Y243 K249 L250 A303	R152-I246 HydrophobicContact CB-CD1 4.05Å; W153-I246 HydrophobicContact CB-CD1 4.05Å; W153-I246 HydrophobicContact CB-CG1 4.26Å; I156-I246 HydrophobicContact CD1-CG1 4.48Å; I156-I246 HydrophobicContact CD1-CG2 3.8Å; I156-I246 HydrophobicContact CG2-CG2 4.39Å; A242-I246 VanDerWaalsContact O-CG1 3.26Å; A242-I246 WeakPolarHBondContact O-CG1 3.3Å; A242-I246 PolarHBondContact O-N 3.43Å; Y243-I246 HydrophobicContact CD1-CD1 3.9Å; Y243-I246 HydrophobicContact CE1-CD1 4.15Å; Y243-I246 PolarHBondContact O-N 2.89Å; I246-K249 PolarHBondContact O-N 2.98Å; I246-L250 HydrophobicContact CG2-CD1 3.71Å; I246-L250 HydrophobicContact CG2-CG 4.32Å; I246-L250 WeakPolarHBondContact O-CB 3.45Å; I246-L250 WeakPolarHBondContact O-CG 3.36Å; I246-L250 PolarHBondContact O-N 2.88Å; I246-A303 HydrophobicContact CG2-CB 4.04Å
247	F	87.9	Confident	80.6	Confident	88 Å²	88	74.4 Å²	74.4	39%	0.386	38%	0.376	S	S	.	.	H	α-helix	trans	-62.2	-50.4	-179.8	-177.5	-95.4	0	0	0	110.9	Y243 L244 Q245 K249 L250 W251	Y243-F247 VanDerWaalsContact O-CB 3.26Å; Y243-F247 WeakPolarHBondContact O-CB 3.41Å; Y243-F247 PolarHBondContact O-N 2.85Å; L244-F247 PolarHBondContact O-N 3.34Å; Q245-F247 VanDerWaalsContact C-N 3.32Å; Q245-F247 PolarHBondContact O-N 3.46Å; F247-K249 VanDerWaalsContact C-N 3.28Å; F247-K249 PolarHBondContact O-N 3.44Å; F247-L250 PolarHBondContact O-N 3.32Å; F247-W251 HydrophobicContact CB-CE3 4.5Å; F247-W251 AromaticContact CD2-CD2 3.83Å; F247-W251 HydrophobicContact CD2-CD2 3.83Å; F247-W251 AromaticContact CD2-CE3 3.41Å; F247-W251 HydrophobicContact CD2-CE3 3.41Å; F247-W251 VanDerWaalsContact CD2-CE3 3.41Å; F247-W251 HydrophobicContact CD2-CG 4.39Å; F247-W251 HydrophobicContact CD2-CH2 4.44Å; F247-W251 AromaticContact CD2-CZ3 3.77Å; F247-W251 HydrophobicContact CD2-CZ3 3.77Å; F247-W251 HydrophobicContact CE1-CB 4.4Å; F247-W251 HydrophobicContact CE2-CB 4.39Å; F247-W251 AromaticContact CE2-CD2 3.65Å; F247-W251 HydrophobicContact CE2-CD2 3.65Å; F247-W251 AromaticContact CE2-CE3 3.77Å; F247-W251 HydrophobicContact CE2-CE3 3.77Å; F247-W251 AromaticContact CE2-CG 3.93Å; F247-W251 HydrophobicContact CE2-CG 3.93Å; F247-W251 HydrophobicContact CE2-CZ3 4.29Å; F247-W251 HydrophobicContact CG-CE3 4.08Å; F247-W251 HydrophobicContact CZ-CB 4.23Å; F247-W251 HydrophobicContact CZ-CD2 4.34Å; F247-W251 HydrophobicContact CZ-CG 4.14Å; F247-W251 WeakPolarHBondContact O-CB 3.31Å; F247-W251 PolarHBondContact O-N 3.43Å
248	R	87.8	Confident	78.4	Confident	170 Å²	170	73.2 Å²	73.2	64%	0.642	37%	0.367	S	S	*	.	I	π-helix	trans	-56.8	-41.5	175.3	-72.9	179.1	115.3	104.1	1.9	111.9	L244 Q245 C252 R253	L244-R248 WeakPolarHBondContact O-CB 3.14Å; L244-R248 VanDerWaalsContact O-CG 3.28Å; L244-R248 WeakPolarHBondContact O-CG 3.3Å; L244-R248 PolarHBondContact O-N 3.43Å; Q245-R248 PolarHBondContact O-N 2.77Å; R248-C252 CarbonylContact O-C 3.56Å; R248-C252 WeakPolarHBondContact O-CA 3.24Å; R248-C252 VanDerWaalsContact O-CB 3.25Å; R248-C252 WeakPolarHBondContact O-CB 3.4Å; R248-C252 PolarHBondContact O-N 2.96Å; R248-R253 PolarHBondContact O-N 3.36Å
249	K	85.7	Confident	76	Confident	57 Å²	57	70.1 Å²	70.1	25%	0.248	36%	0.356	C	S	.	.	I	π-helix	trans	-70.7	-36.7	179.4	-170.7	68.7	175.9	-168.9	0	113	I156 Q245 I246 F247 R253	I156-K249 HydrophobicContact CG2-CG 4.47Å; Q245-K249 WeakPolarHBondContact O-CB 3.38Å; Q245-K249 PolarHBondContact O-N 3.23Å; I246-K249 PolarHBondContact O-N 2.98Å; F247-K249 VanDerWaalsContact C-N 3.28Å; F247-K249 PolarHBondContact O-N 3.44Å; K249-R253 HydrophobicContact CD-CB 4.27Å
250	L	82.7	Confident	73.7	Confident	4 Å²	4	73 Å²	73	2%	0.021	38%	0.376	C	S	.	.	I	π-helix	trans	-85.8	-28.8	-176.7	-75.6	178.7	0	0	0	114.1	I156 I246 F247 I255 R300 A303	I156-L250 HydrophobicContact CD1-CD1 4.18Å; I156-L250 HydrophobicContact CG2-CD1 4.26Å; I156-L250 HydrophobicContact CG2-CD2 3.8Å; I156-L250 HydrophobicContact CG2-CG 3.77Å; I246-L250 HydrophobicContact CG2-CD1 3.71Å; I246-L250 HydrophobicContact CG2-CG 4.32Å; I246-L250 WeakPolarHBondContact O-CB 3.45Å; I246-L250 WeakPolarHBondContact O-CG 3.36Å; I246-L250 PolarHBondContact O-N 2.88Å; F247-L250 PolarHBondContact O-N 3.32Å; L250-I255 HydrophobicContact CD2-CD1 4.42Å; L250-R300 HydrophobicContact CB-CG 4.33Å; L250-R300 HydrophobicContact CD1-CG 4.22Å; L250-R300 PolarHBondContact O-NE 2.77Å; L250-R300 VanDerWaalsContact O-NE 3.16Å; L250-R300 PolarHBondContact O-NH2 3.19Å; L250-A303 HydrophobicContact CD1-CB 4.04Å
251	W	81.1	Confident	71.5	Confident	100 Å²	100	72.3 Å²	72.3	38%	0.379	37%	0.372	S	S	.	.	I	π-helix	trans	-109.2	-38.8	-176.6	-82.7	-97.6	0	0	0	113.7	F247 R300	F247-W251 HydrophobicContact CB-CE3 4.5Å; F247-W251 AromaticContact CD2-CD2 3.83Å; F247-W251 HydrophobicContact CD2-CD2 3.83Å; F247-W251 AromaticContact CD2-CE3 3.41Å; F247-W251 HydrophobicContact CD2-CE3 3.41Å; F247-W251 VanDerWaalsContact CD2-CE3 3.41Å; F247-W251 HydrophobicContact CD2-CG 4.39Å; F247-W251 HydrophobicContact CD2-CH2 4.44Å; F247-W251 AromaticContact CD2-CZ3 3.77Å; F247-W251 HydrophobicContact CD2-CZ3 3.77Å; F247-W251 HydrophobicContact CE1-CB 4.4Å; F247-W251 HydrophobicContact CE2-CB 4.39Å; F247-W251 AromaticContact CE2-CD2 3.65Å; F247-W251 HydrophobicContact CE2-CD2 3.65Å; F247-W251 AromaticContact CE2-CE3 3.77Å; F247-W251 HydrophobicContact CE2-CE3 3.77Å; F247-W251 AromaticContact CE2-CG 3.93Å; F247-W251 HydrophobicContact CE2-CG 3.93Å; F247-W251 HydrophobicContact CE2-CZ3 4.29Å; F247-W251 HydrophobicContact CG-CE3 4.08Å; F247-W251 HydrophobicContact CZ-CB 4.23Å; F247-W251 HydrophobicContact CZ-CD2 4.34Å; F247-W251 HydrophobicContact CZ-CG 4.14Å; F247-W251 WeakPolarHBondContact O-CB 3.31Å; F247-W251 PolarHBondContact O-N 3.43Å; W251-R300 HydrophobicContact CH2-CB 3.86Å; W251-R300 HydrophobicContact CH2-CG 3.82Å; W251-R300 HydrophobicContact CZ2-CB 4.04Å; W251-R300 HydrophobicContact CZ2-CG 3.95Å; W251-R300 HydrophobicContact CZ3-CG 4.17Å
252	C	73.2	Confident	69	Low	92 Å²	92	71.7 Å²	71.7	62%	0.622	37%	0.372	S	S	*	.	I	π-helix	trans	-97.5	-35.4	-173.8	-49.8	0	0	0	0	113	R248	R248-C252 CarbonylContact O-C 3.56Å; R248-C252 WeakPolarHBondContact O-CA 3.24Å; R248-C252 VanDerWaalsContact O-CB 3.25Å; R248-C252 WeakPolarHBondContact O-CB 3.4Å; R248-C252 PolarHBondContact O-N 2.96Å
253	R	60.6	Low	66.4	Low	177 Å²	177	78.2 Å²	78.2	67%	0.668	40%	0.401	S	S	*	.	S	Bend	trans	-93.3	117	175.1	-73.8	-173.1	157.8	-171.6	-9.1	110	R248 K249 I255	R248-R253 PolarHBondContact O-N 3.36Å; K249-R253 HydrophobicContact CD-CB 4.27Å; R253-I255 PolarHBondContact O-N 2.91Å; R253-I255 VanDerWaalsContact O-N 3.15Å
254	Q	52.6	Low	64.1	Low	123 Å²	123	86 Å²	86	58%	0.575	43%	0.43	S	S	*	.	P	Polyproline II helix	trans	-58.2	116.5	169.4	-150.3	146.9	20.5	0	0	107.9	P256 T258	Q254-P256 WeakPolarHBondContact O-CD 3.02Å; Q254-P256 VanDerWaalsContact O-N 3.16Å; Q254-T258 WeakPolarHBondContact CG-OG1 3.33Å
255	I	53.7	Low	61.6	Low	50 Å²	50	90.7 Å²	90.7	26%	0.256	45%	0.447	S	S	.	.	P	Polyproline II helix	trans	-58.7	122.1	178.6	-63.6	166.7	0	0	0	106.5	L250 R253 G257 T258 I296	L250-I255 HydrophobicContact CD2-CD1 4.42Å; R253-I255 PolarHBondContact O-N 2.91Å; R253-I255 VanDerWaalsContact O-N 3.15Å; I255-G257 PolarHBondContact O-N 2.96Å; I255-T258 PolarHBondContact O-N 3.29Å; I255-T258 PolarHBondContact O-OG1 3.02Å; I255-I296 HydrophobicContact CD1-CB 4.48Å; I255-I296 HydrophobicContact CD1-CD1 3.7Å; I255-I296 HydrophobicContact CD1-CG1 3.66Å; I255-I296 HydrophobicContact CD1-CG2 4Å
256	P	41.3	Very low	58.9	Low	112 Å²	112	96.6 Å²	96.6	73%	0.727	47%	0.465	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.1	115.4	-179.4	-21.7	31	0	0	0	108.7	Q254	Q254-P256 WeakPolarHBondContact O-CD 3.02Å; Q254-P256 VanDerWaalsContact O-N 3.16Å
257	G	51.8	Low	56.1	Low	39 Å²	39	105 Å²	105	40%	0.402	50%	0.501	S	S	.	.	T	Hydrogen-bonded Turn	trans	132.2	-25.6	-168.2	0	0	0	0	0	114	I255 S260	I255-G257 PolarHBondContact O-N 2.96Å; G257-S260 PolarHBondContact O-OG 2.95Å
258	T	49.8	Very low	53.8	Low	36 Å²	36	106.2 Å²	106.2	22%	0.221	52%	0.519	C	S	.	.	S	Bend	trans	-85	-21.1	-177.1	40.9	0	0	0	0	115.2	Q254 I255 S260 V261 V262 I296	Q254-T258 WeakPolarHBondContact CG-OG1 3.33Å; I255-T258 PolarHBondContact O-N 3.29Å; I255-T258 PolarHBondContact O-OG1 3.02Å; T258-S260 VanDerWaalsContact C-N 3.32Å; T258-S260 PolarHBondContact O-N 3.42Å; T258-V261 PolarHBondContact O-N 2.99Å; T258-V262 PolarHBondContact O-N 2.98Å; T258-I296 HydrophobicContact CG2-CD1 4.25Å
259	S	45.1	Very low	51.7	Low	54 Å²	54	106.4 Å²	106.4	38%	0.378	53%	0.531	S	S	.	.	H	α-helix	trans	-66.9	-30.9	-177.1	-41	0	0	0	0	113.1	V261 Q263	S259-V261 PolarHBondContact O-N 3.44Å; S259-Q263 WeakPolarHBondContact O-CB 3.11Å; S259-Q263 PolarHBondContact O-N 3.48Å; S259-Q263 VanDerWaalsContact O-N 3.13Å
260	S	46.1	Very low	49.4	Very low	64 Å²	64	111.7 Å²	111.7	45%	0.448	56%	0.557	S	S	.	*	H	α-helix	trans	-75.2	-11	179.6	58.3	0	0	0	0	113.9	G257 T258 R264	G257-S260 PolarHBondContact O-OG 2.95Å; T258-S260 VanDerWaalsContact C-N 3.32Å; T258-S260 PolarHBondContact O-N 3.42Å; S260-R264 PolarHBondContact O-NE 2.82Å; S260-R264 PolarHBondContact O-NH2 3.46Å
261	V	48.6	Very low	47.4	Very low	48 Å²	48	117.7 Å²	117.7	29%	0.291	60%	0.596	S	S	.	*	H	α-helix	trans	-101.3	-40.5	179.6	-178.1	0	0	0	0	111.3	T258 S259 V289	T258-V261 PolarHBondContact O-N 2.99Å; S259-V261 PolarHBondContact O-N 3.44Å; V261-V289 HydrophobicContact CB-CG1 4.35Å; V261-V289 HydrophobicContact CG1-CG1 3.72Å; V261-V289 HydrophobicContact CG2-CB 4.47Å; V261-V289 HydrophobicContact CG2-CG1 3.66Å; V261-V289 HydrophobicContact CG2-CG2 3.89Å
262	V	42.1	Very low	45.3	Very low	83 Å²	83	118.7 Å²	118.7	50%	0.503	61%	0.613	S	S	.	*	H	α-helix	trans	-77.3	-35.8	178.1	178.5	0	0	0	0	112	T258 R264 K265	T258-V262 PolarHBondContact O-N 2.98Å; V262-R264 PolarHBondContact O-N 3.14Å; V262-K265 PolarHBondContact O-N 2.82Å
263	Q	38.6	Very low	43.8	Very low	145 Å²	145	119.4 Å²	119.4	68%	0.678	62%	0.619	S	S	*	*	G	3₁₀ helix	trans	-66	-24.9	173.9	-85.1	-178.1	-48.2	0	0	113.4	S259 K265 W266	S259-Q263 WeakPolarHBondContact O-CB 3.11Å; S259-Q263 PolarHBondContact O-N 3.48Å; S259-Q263 VanDerWaalsContact O-N 3.13Å; Q263-K265 PolarHBondContact O-N 3.46Å; Q263-W266 PolarHBondContact O-N 3.4Å
264	R	43.7	Very low	42.8	Very low	178 Å²	178	119.4 Å²	119.4	67%	0.672	63%	0.627	S	S	*	*	G	3₁₀ helix	trans	-73	-15.4	177.7	-103.3	-175.5	-78.2	168.2	-6.9	113.8	S260 V262 W266	S260-R264 PolarHBondContact O-NE 2.82Å; S260-R264 PolarHBondContact O-NH2 3.46Å; V262-R264 PolarHBondContact O-N 3.14Å; R264-W266 PolarHBondContact O-N 3.37Å
265	K	38.4	Very low	42.3	Very low	188 Å²	188	119.6 Å²	119.6	82%	0.817	64%	0.638	S	S	*	*	G	3₁₀ helix	trans	-73.7	-10.3	172.1	-115.5	-173.6	178.1	-169.1	0	113.5	V262 Q263	V262-K265 PolarHBondContact O-N 2.82Å; Q263-K265 PolarHBondContact O-N 3.46Å
266	W	35.5	Very low	41.7	Very low	219 Å²	219	129 Å²	129	83%	0.83	67%	0.671	S	S	*	*	S	Bend	trans	-122.3	4.3	-171.6	-76.5	96.4	0	0	0	115.4	Q263 R264 P268	Q263-W266 PolarHBondContact O-N 3.4Å; R264-W266 PolarHBondContact O-N 3.37Å; W266-P268 WeakPolarHBondContact O-CD 3.44Å
267	K	32.2	Very low	41.7	Very low	177 Å²	177	126.6 Å²	126.6	77%	0.77	67%	0.666	S	S	*	*	S	Bend	trans	-93.2	112.1	162.4	-78.3	-167.7	174.8	-169.1	0	108	L269	K267-L269 PolarHBondContact O-N 3.12Å
268	P	39.6	Very low	41.5	Very low	115 Å²	115	131.3 Å²	131.3	75%	0.747	69%	0.689	S	S	*	*			trans	-52.8	134.2	161	-15.2	28.2	0	0	0	107.1	W266 Q270	W266-P268 WeakPolarHBondContact O-CD 3.44Å; P268-Q270 PolarHBondContact O-N 2.85Å
269	L	42.6	Very low	41.4	Very low	174 Å²	174	133 Å²	133	91%	0.911	71%	0.714	S	S	*	*			trans	-54.2	107.9	172	-84.8	91.4	0	0	0	108.2	K267	K267-L269 PolarHBondContact O-N 3.12Å
270	Q	38.7	Very low	41.8	Very low	168 Å²	168	139.6 Å²	139.6	79%	0.785	74%	0.739	S	S	*	*			trans	-72.7	132.2	156.4	-79.9	-176.4	-26	0	0	107.3	P268 V272	P268-Q270 PolarHBondContact O-N 2.85Å; Q270-V272 PolarHBondContact O-N 3.16Å
271	P	39.4	Very low	42.1	Very low	130 Å²	130	139.4 Å²	139.4	84%	0.844	74%	0.736	S	S	*	*			trans	-76.1	93.9	176	30.6	-29.6	0	0	0	108.1
272	V	37.4	Very low	42.4	Very low	121 Å²	121	142.7 Å²	142.7	73%	0.733	76%	0.757	S	S	*	*			trans	-88.9	105.3	166.4	-179	0	0	0	0	107.5	Q270 Q274	Q270-V272 PolarHBondContact O-N 3.16Å; V272-Q274 PolarHBondContact O-N 2.73Å
273	S	41.7	Very low	43	Very low	106 Å²	106	147.2 Å²	147.2	74%	0.741	77%	0.77	S	S	*	*			trans	-68.5	111.2	165.2	38.4	0	0	0	0	109.5
274	Q	39.5	Very low	43.8	Very low	178 Å²	178	143.8 Å²	143.8	83%	0.832	76%	0.761	S	S	*	*			trans	-167.7	154	152.1	-107.1	168.4	27.5	0	0	111.9	V272	V272-Q274 PolarHBondContact O-N 2.73Å
275	P	41.7	Very low	44.6	Very low	126 Å²	126	144.8 Å²	144.8	82%	0.818	77%	0.765	S	S	*	*			trans	-82.2	155.5	-147.8	31.5	-34.4	0	0	0	114.9
276	R	41.7	Very low	45.8	Very low	249 Å²	249	141.4 Å²	141.4	94%	0.94	76%	0.755	S	S	*	*			trans	-86.4	114.3	-167.4	-172.7	-177.1	-85.8	-176.7	-6	110.9
277	G	40.7	Very low	47.4	Very low	61 Å²	61	134.8 Å²	134.8	63%	0.629	74%	0.742	S	S	*	*			trans	-85.4	155.7	162.1	0	0	0	0	0	112
278	P	48	Very low	49.3	Very low	137 Å²	137	128.9 Å²	128.9	89%	0.89	73%	0.726	S	S	*	*			trans	-86.5	136.3	-163.2	25.7	-17.1	0	0	0	113.6
279	G	48.8	Very low	50.8	Low	72 Å²	72	125.3 Å²	125.3	74%	0.742	70%	0.702	S	S	*	*			trans	90.9	98.9	136.9	0	0	0	0	0	119.2
280	Q	53.1	Low	52.3	Low	193 Å²	193	119.6 Å²	119.6	90%	0.902	68%	0.68	S	S	*	*			trans	84.4	136.9	157	-68.8	-172.1	0.8	0	0	120.9
281	P	52.6	Low	54	Low	59 Å²	59	114.3 Å²	114.3	38%	0.383	67%	0.665	S	S	.	*				-137.6	133.5	-51.1	27.8	-7.8	0	0	0	112.2	K283 S284	P281-K283 HydrophobicContact CB-CB 4.17Å; P281-K283 PolarHBondContact O-N 2.87Å; P281-S284 PolarHBondContact O-N 3.4Å
282	T	53.7	Low	55.7	Low	118 Å²	118	112.9 Å²	112.9	72%	0.724	65%	0.647	S	S	*	*	H	α-helix	trans	-49.2	-27	160.5	5.5	0	0	0	0	112.6	I286	T282-I286 VanDerWaalsContact O-CG1 3.31Å; T282-I286 WeakPolarHBondContact O-CG1 2.9Å; T282-I286 PolarHBondContact O-N 2.84Å
283	K	54.6	Low	57.5	Low	178 Å²	178	111 Å²	111	77%	0.774	63%	0.633	S	S	*	*	H	α-helix	trans	-63.6	-37.2	173.2	-64.6	-175.6	177.3	-178.9	0	114	P281 I286 S287	P281-K283 HydrophobicContact CB-CB 4.17Å; P281-K283 PolarHBondContact O-N 2.87Å; K283-I286 PolarHBondContact O-N 3.33Å; K283-S287 WeakPolarHBondContact O-CB 3.27Å; K283-S287 PolarHBondContact O-N 3.21Å
284	S	56.8	Low	59.2	Low	72 Å²	72	113.8 Å²	113.8	50%	0.503	63%	0.631	S	S	.	*	H	α-helix	trans	-66.9	-42.3	178.2	167.3	0	0	0	0	111.5	P281 S287 A288	P281-S284 PolarHBondContact O-N 3.4Å; S284-S287 PolarHBondContact O-N 3.32Å; S284-A288 PolarHBondContact O-N 3.17Å
285	R	59.4	Low	60.9	Low	199 Å²	199	110.2 Å²	110.2	75%	0.751	61%	0.614	S	S	*	*	H	α-helix	trans	-67.3	-36.3	177.1	-70.3	-177.2	178.3	178.2	-0.3	113.1	V289	R285-V289 WeakPolarHBondContact O-CG2 3.3Å; R285-V289 PolarHBondContact O-N 2.92Å
286	I	64.3	Low	62.5	Low	117 Å²	117	105.5 Å²	105.5	60%	0.6	58%	0.582	S	S	*	*	H	α-helix	trans	-68.7	-40.3	175.2	-66.5	166.3	0	0	0	110.8	T282 K283 V289 A290	T282-I286 VanDerWaalsContact O-CG1 3.31Å; T282-I286 WeakPolarHBondContact O-CG1 2.9Å; T282-I286 PolarHBondContact O-N 2.84Å; K283-I286 PolarHBondContact O-N 3.33Å; I286-V289 PolarHBondContact O-N 2.03Å; I286-A290 WeakPolarHBondContact O-CB 3.21Å; I286-A290 PolarHBondContact O-N 3.31Å
287	S	69.5	Low	64.3	Low	80 Å²	80	102.5 Å²	102.5	56%	0.559	57%	0.571	S	S	*	*	H	α-helix	trans	-61.4	-44.2	175.2	-173.3	0	0	0	0	112.1	K283 S284 A290 A291	K283-S287 WeakPolarHBondContact O-CB 3.27Å; K283-S287 PolarHBondContact O-N 3.21Å; S284-S287 PolarHBondContact O-N 3.32Å; S287-A290 PolarHBondContact O-N 2.89Å; S287-A291 WeakPolarHBondContact O-CB 3.39Å; S287-A291 PolarHBondContact O-N 3.23Å
288	A	70.8	Confident	66	Low	54 Å²	54	102.2 Å²	102.2	45%	0.446	56%	0.563	S	S	.	*	H	α-helix	trans	-61.5	-45.8	177.1	0	0	0	0	0	112.6	S284 A290 A291 E292	S284-A288 PolarHBondContact O-N 3.17Å; A288-A290 PolarHBondContact O-N 2.81Å; A288-A291 WeakPolarHBondContact O-CB 3.28Å; A288-A291 PolarHBondContact O-N 3.09Å; A288-E292 PolarHBondContact O-N 3.22Å
289	V	72.4	Confident	67.5	Low	39 Å²	39	99.4 Å²	99.4	24%	0.236	53%	0.534	C	S	.	.	H	α-helix	trans	-64.2	-40.8	176.8	171.2	0	0	0	0	111.6	V261 R285 I286 A291 E292 I293	V261-V289 HydrophobicContact CB-CG1 4.35Å; V261-V289 HydrophobicContact CG1-CG1 3.72Å; V261-V289 HydrophobicContact CG2-CB 4.47Å; V261-V289 HydrophobicContact CG2-CG1 3.66Å; V261-V289 HydrophobicContact CG2-CG2 3.89Å; R285-V289 WeakPolarHBondContact O-CG2 3.3Å; R285-V289 PolarHBondContact O-N 2.92Å; I286-V289 PolarHBondContact O-N 2.03Å; V289-A291 VanDerWaalsContact C-N 3.33Å; V289-A291 PolarHBondContact O-N 3.3Å; V289-E292 PolarHBondContact O-N 3.35Å; V289-I293 HydrophobicContact CG1-CD1 3.94Å; V289-I293 WeakPolarHBondContact O-CG1 3.46Å; V289-I293 PolarHBondContact O-N 2.8Å
290	A	73.3	Confident	69.1	Low	55 Å²	55	100.2 Å²	100.2	46%	0.455	52%	0.515	S	S	.	.	H	α-helix	trans	-63.8	-39.3	176.2	0	0	0	0	0	111.9	I286 S287 A288 K294	I286-A290 WeakPolarHBondContact O-CB 3.21Å; I286-A290 PolarHBondContact O-N 3.31Å; S287-A290 PolarHBondContact O-N 2.89Å; A288-A290 PolarHBondContact O-N 2.81Å; A290-K294 WeakPolarHBondContact O-CB 3.29Å; A290-K294 PolarHBondContact O-N 3.24Å
291	A	73.9	Confident	70.5	Confident	57 Å²	57	95.6 Å²	95.6	47%	0.471	49%	0.492	S	S	.	.	H	α-helix	trans	-63.7	-44	175.4	0	0	0	0	0	112	S287 A288 V289 K294 Q295	S287-A291 WeakPolarHBondContact O-CB 3.39Å; S287-A291 PolarHBondContact O-N 3.23Å; A288-A291 WeakPolarHBondContact O-CB 3.28Å; A288-A291 PolarHBondContact O-N 3.09Å; V289-A291 VanDerWaalsContact C-N 3.33Å; V289-A291 PolarHBondContact O-N 3.3Å; A291-K294 PolarHBondContact O-N 3.36Å; A291-Q295 WeakPolarHBondContact O-CB 3.44Å; A291-Q295 PolarHBondContact O-N 3.35Å
292	E	75.3	Confident	71.8	Confident	100 Å²	100	95.1 Å²	95.1	47%	0.467	49%	0.488	S	S	.	.	H	α-helix	trans	-62.4	-45.6	176.5	-73.9	-170.3	159.9	0	0	112.4	A288 V289 K294 Q295 I296	A288-E292 PolarHBondContact O-N 3.22Å; V289-E292 PolarHBondContact O-N 3.35Å; E292-K294 VanDerWaalsContact C-N 3.33Å; E292-K294 PolarHBondContact O-N 3.34Å; E292-Q295 PolarHBondContact O-N 3.08Å; E292-I296 WeakPolarHBondContact O-CG1 3.35Å; E292-I296 PolarHBondContact O-N 3.08Å
293	I	76	Confident	73.1	Confident	82 Å²	82	89.8 Å²	89.8	42%	0.421	46%	0.456	S	S	.	.	H	α-helix	trans	-60.9	-43.5	176.9	-68.1	169.6	0	0	0	110.6	V289 Q295 I296 R297	V289-I293 HydrophobicContact CG1-CD1 3.94Å; V289-I293 WeakPolarHBondContact O-CG1 3.46Å; V289-I293 PolarHBondContact O-N 2.8Å; I293-Q295 VanDerWaalsContact C-N 3.33Å; I293-Q295 PolarHBondContact O-N 3.1Å; I293-I296 PolarHBondContact O-N 3.4Å; I293-R297 WeakPolarHBondContact O-CB 3.39Å; I293-R297 PolarHBondContact O-N 2.96Å
294	K	76.1	Confident	74.6	Confident	163 Å²	163	88 Å²	88	71%	0.709	44%	0.444	S	S	*	.	H	α-helix	trans	-61.9	-42	176.7	-171.3	178	-178.6	-179.6	0	111	A290 A291 E292 R297 A298	A290-K294 WeakPolarHBondContact O-CB 3.29Å; A290-K294 PolarHBondContact O-N 3.24Å; A291-K294 PolarHBondContact O-N 3.36Å; E292-K294 VanDerWaalsContact C-N 3.33Å; E292-K294 PolarHBondContact O-N 3.34Å; K294-R297 PolarHBondContact O-N 3.47Å; K294-A298 WeakPolarHBondContact O-CB 3.31Å; K294-A298 PolarHBondContact O-N 3.5Å
295	Q	75.9	Confident	75.9	Confident	103 Å²	103	85.1 Å²	85.1	48%	0.481	42%	0.423	S	S	.	.	H	α-helix	trans	-64.4	-43.8	178	-166.7	-177.7	11	0	0	112	A291 E292 I293 A298 R299	A291-Q295 WeakPolarHBondContact O-CB 3.44Å; A291-Q295 PolarHBondContact O-N 3.35Å; E292-Q295 PolarHBondContact O-N 3.08Å; I293-Q295 VanDerWaalsContact C-N 3.33Å; I293-Q295 PolarHBondContact O-N 3.1Å; Q295-A298 PolarHBondContact O-N 2.68Å; Q295-R299 WeakPolarHBondContact O-CG 3.23Å; Q295-R299 PolarHBondContact O-N 3.45Å
296	I	75.1	Confident	77.1	Confident	28 Å²	28	75.9 Å²	75.9	14%	0.144	39%	0.388	C	S	.	.	H	α-helix	trans	-64.1	-43.7	177.2	-66.2	164.5	0	0	0	110.9	I255 T258 E292 I293 A298 R299 R300	I255-I296 HydrophobicContact CD1-CB 4.48Å; I255-I296 HydrophobicContact CD1-CD1 3.7Å; I255-I296 HydrophobicContact CD1-CG1 3.66Å; I255-I296 HydrophobicContact CD1-CG2 4Å; T258-I296 HydrophobicContact CG2-CD1 4.25Å; E292-I296 WeakPolarHBondContact O-CG1 3.35Å; E292-I296 PolarHBondContact O-N 3.08Å; I293-I296 PolarHBondContact O-N 3.4Å; I296-A298 VanDerWaalsContact C-N 3.32Å; I296-A298 PolarHBondContact O-N 3.42Å; I296-R299 PolarHBondContact O-N 2.96Å; I296-R300 PolarHBondContact O-N 3.31Å
297	R	79.2	Confident	78.2	Confident	186 Å²	186	74.5 Å²	74.5	70%	0.702	38%	0.381	S	S	*	.	H	α-helix	trans	-61.1	-42.2	177	-172.9	-178.3	-72.3	174.8	-2.8	111.3	I293 K294 R300 K301	I293-R297 WeakPolarHBondContact O-CB 3.39Å; I293-R297 PolarHBondContact O-N 2.96Å; K294-R297 PolarHBondContact O-N 3.47Å; R297-R300 PolarHBondContact O-N 3Å; R297-K301 PolarHBondContact O-N 2.86Å
298	A	76.6	Confident	79.3	Confident	55 Å²	55	73.1 Å²	73.1	46%	0.455	37%	0.368	S	S	.	.	H	α-helix	trans	-60.5	-46.2	174.7	0	0	0	0	0	111.6	K294 Q295 I296 R300 K301 T302	K294-A298 WeakPolarHBondContact O-CB 3.31Å; K294-A298 PolarHBondContact O-N 3.5Å; Q295-A298 PolarHBondContact O-N 2.68Å; I296-A298 VanDerWaalsContact C-N 3.32Å; I296-A298 PolarHBondContact O-N 3.42Å; A298-R300 PolarHBondContact O-N 2.92Å; A298-K301 PolarHBondContact O-N 3.29Å; A298-T302 PolarHBondContact O-N 3.04Å; A298-T302 PolarHBondContact O-OG1 3.38Å
299	R	79.3	Confident	80.2	Confident	77 Å²	77	70.6 Å²	70.6	29%	0.291	35%	0.348	S	S	.	.	H	α-helix	trans	-59.4	-43.3	176.9	-70.4	176.5	-172.8	-161.5	6.1	112.6	Q295 I296 K301 T302 A303	Q295-R299 WeakPolarHBondContact O-CG 3.23Å; Q295-R299 PolarHBondContact O-N 3.45Å; I296-R299 PolarHBondContact O-N 2.96Å; R299-K301 PolarHBondContact O-N 3.43Å; R299-T302 PolarHBondContact O-N 3.49Å; R299-A303 WeakPolarHBondContact O-CB 3.48Å; R299-A303 PolarHBondContact O-N 3.02Å
300	R	83.1	Confident	81.1	Confident	90 Å²	90	69.3 Å²	69.3	34%	0.34	34%	0.339	S	S	.	.	H	α-helix	trans	-63	-39.7	175.8	-74	-176.4	-177.9	168.8	0.9	112.6	L250 W251 I296 R297 A298 R304	L250-R300 HydrophobicContact CB-CG 4.33Å; L250-R300 HydrophobicContact CD1-CG 4.22Å; L250-R300 PolarHBondContact O-NE 2.77Å; L250-R300 VanDerWaalsContact O-NE 3.16Å; L250-R300 PolarHBondContact O-NH2 3.19Å; W251-R300 HydrophobicContact CH2-CB 3.86Å; W251-R300 HydrophobicContact CH2-CG 3.82Å; W251-R300 HydrophobicContact CZ2-CB 4.04Å; W251-R300 HydrophobicContact CZ2-CG 3.95Å; W251-R300 HydrophobicContact CZ3-CG 4.17Å; I296-R300 PolarHBondContact O-N 3.31Å; R297-R300 PolarHBondContact O-N 3Å; A298-R300 PolarHBondContact O-N 2.92Å; R300-R304 WeakPolarHBondContact O-CB 3.37Å; R300-R304 PolarHBondContact O-N 3.23Å
301	K	82.7	Confident	82.1	Confident	96 Å²	96	71.5 Å²	71.5	42%	0.417	34%	0.343	S	S	.	.	H	α-helix	trans	-63.9	-46.6	176.8	-176	174	175.6	174.2	0	111	R297 A298 R299 R304 M305 L367	R297-K301 PolarHBondContact O-N 2.86Å; A298-K301 PolarHBondContact O-N 3.29Å; R299-K301 PolarHBondContact O-N 3.43Å; K301-R304 PolarHBondContact O-N 2.91Å; K301-M305 PolarHBondContact O-N 3.05Å; K301-L367 WeakPolarHBondContact CE-O 3.34Å
302	T	79.1	Confident	83.1	Confident	49 Å²	49	70.5 Å²	70.5	30%	0.301	33%	0.331	S	S	.	.	H	α-helix	trans	-63.3	-45.4	176.5	-56.1	0	0	0	0	112	A298 R299 R304 M305 L306	A298-T302 PolarHBondContact O-N 3.04Å; A298-T302 PolarHBondContact O-OG1 3.38Å; R299-T302 PolarHBondContact O-N 3.49Å; T302-R304 VanDerWaalsContact C-N 3.34Å; T302-R304 PolarHBondContact O-N 3.37Å; T302-M305 WeakPolarHBondContact O-CB 3.38Å; T302-M305 PolarHBondContact O-N 2.98Å; T302-L306 HydrophobicContact CG2-CD1 4.07Å; T302-L306 WeakPolarHBondContact O-CG 3.42Å; T302-L306 PolarHBondContact O-N 2.97Å
303	A	81.4	Confident	83.9	Confident	6 Å²	6	65.9 Å²	65.9	5%	0.05	31%	0.309	C	S	.	.	H	α-helix	trans	-61.2	-42	178	0	0	0	0	0	112.2	I246 L250 R299 L306 M307	I246-A303 HydrophobicContact CG2-CB 4.04Å; L250-A303 HydrophobicContact CD1-CB 4.04Å; R299-A303 WeakPolarHBondContact O-CB 3.48Å; R299-A303 PolarHBondContact O-N 3.02Å; A303-L306 PolarHBondContact O-N 3.47Å; A303-M307 WeakPolarHBondContact O-CB 3.31Å; A303-M307 PolarHBondContact O-N 3.39Å
304	R	85.6	Confident	84.8	Confident	140 Å²	140	62.6 Å²	62.6	53%	0.528	30%	0.295	S	S	.	.	H	α-helix	trans	-62.5	-45.6	175.7	-170.2	-167	-41.1	178.2	4.6	112.1	R300 K301 T302 L306 M307 V308	R300-R304 WeakPolarHBondContact O-CB 3.37Å; R300-R304 PolarHBondContact O-N 3.23Å; K301-R304 PolarHBondContact O-N 2.91Å; T302-R304 VanDerWaalsContact C-N 3.34Å; T302-R304 PolarHBondContact O-N 3.37Å; R304-L306 VanDerWaalsContact C-N 3.31Å; R304-L306 PolarHBondContact O-N 3.23Å; R304-M307 PolarHBondContact O-N 2.91Å; R304-V308 WeakPolarHBondContact O-CG2 3.14Å; R304-V308 PolarHBondContact O-N 3.33Å
305	M	84.9	Confident	85.8	Confident	11 Å²	11	59.4 Å²	59.4	5%	0.054	28%	0.284	C	S	.	.	H	α-helix	trans	-54	-50.1	175.9	171.1	-172	169.2	0	0	111	I93 K301 T302 M307 V308 V309 Y364 L367	I93-M305 HydrophobicContact CD1-CE 4.34Å; K301-M305 PolarHBondContact O-N 3.05Å; T302-M305 WeakPolarHBondContact O-CB 3.38Å; T302-M305 PolarHBondContact O-N 2.98Å; M305-M307 VanDerWaalsContact C-N 3.34Å; M305-M307 PolarHBondContact O-N 3.48Å; M305-V308 PolarHBondContact O-N 3.34Å; M305-V309 WeakPolarHBondContact O-CG2 3.43Å; M305-V309 PolarHBondContact O-N 3.49Å; M305-V309 VanDerWaalsContact O-N 3.1Å; M305-Y364 HydrophobicContact CE-CD1 3.23Å; M305-Y364 HydrophobicContact CE-CE1 3.86Å; M305-Y364 HydrophobicContact CE-CG 3.92Å; M305-L367 HydrophobicContact CB-CB 3.83Å; M305-L367 HydrophobicContact CB-CD1 4.24Å; M305-L367 HydrophobicContact CG-CB 3.77Å; M305-L367 HydrophobicContact CG-CD1 4.36Å
306	L	84.8	Confident	86.8	Confident	6 Å²	6	55 Å²	55	3%	0.031	27%	0.265	C	S	.	.	H	α-helix	trans	-70.3	-30.1	-177.2	-62.1	172.9	0	0	0	113.2	T89 I148 R152 Y243 T302 A303 R304 V309 L310	T89-L306 HydrophobicContact CG2-CD2 4.48Å; I148-L306 HydrophobicContact CG2-CD1 3.64Å; I148-L306 HydrophobicContact CG2-CD2 3.76Å; I148-L306 HydrophobicContact CG2-CG 4.23Å; R152-L306 HydrophobicContact CG-CD1 3.53Å; Y243-L306 HydrophobicContact CE1-CB 4.07Å; Y243-L306 VanDerWaalsContact OH-CB 3.26Å; Y243-L306 WeakPolarHBondContact OH-CB 3.42Å; T302-L306 HydrophobicContact CG2-CD1 4.07Å; T302-L306 WeakPolarHBondContact O-CG 3.42Å; T302-L306 PolarHBondContact O-N 2.97Å; A303-L306 PolarHBondContact O-N 3.47Å; R304-L306 VanDerWaalsContact C-N 3.31Å; R304-L306 PolarHBondContact O-N 3.23Å; L306-V309 PolarHBondContact O-N 3.29Å; L306-L310 PolarHBondContact O-N 3.11Å
307	M	88.1	Confident	87.8	Confident	88 Å²	88	54.3 Å²	54.3	43%	0.433	26%	0.26	S	S	.	.	H	α-helix	trans	-67.3	-36.9	172.6	-166.8	173	80.5	0	0	112.1	A303 R304 M305 L310 L311	A303-M307 WeakPolarHBondContact O-CB 3.31Å; A303-M307 PolarHBondContact O-N 3.39Å; R304-M307 PolarHBondContact O-N 2.91Å; M305-M307 VanDerWaalsContact C-N 3.34Å; M305-M307 PolarHBondContact O-N 3.48Å; M307-L310 PolarHBondContact O-N 3.35Å; M307-L311 WeakPolarHBondContact O-CB 3.25Å; M307-L311 PolarHBondContact O-N 3.26Å
308	V	92.1	Very high	88.6	Confident	50 Å²	50	49 Å²	49	30%	0.303	25%	0.246	S	C	.	.	H	α-helix	trans	-65.4	-43.8	173.2	173.3	0	0	0	0	110.7	R304 M305 L310 L311 V312 I363 L367	R304-V308 WeakPolarHBondContact O-CG2 3.14Å; R304-V308 PolarHBondContact O-N 3.33Å; M305-V308 PolarHBondContact O-N 3.34Å; V308-L310 VanDerWaalsContact C-N 3.31Å; V308-L310 PolarHBondContact O-N 3.27Å; V308-L311 PolarHBondContact O-N 3.02Å; V308-V312 HydrophobicContact CG1-CG2 4.39Å; V308-V312 WeakPolarHBondContact O-CG2 3.46Å; V308-V312 PolarHBondContact O-N 3.35Å; V308-I363 HydrophobicContact CG1-CG1 4.49Å; V308-I363 HydrophobicContact CG1-CG2 4.16Å; V308-L367 HydrophobicContact CB-CD1 3.8Å; V308-L367 HydrophobicContact CG1-CD1 3.97Å; V308-L367 HydrophobicContact CG2-CD1 3.91Å
309	V	89.3	Confident	89.6	Confident	2 Å²	2	47.8 Å²	47.8	1%	0.012	23%	0.233	C	C	.	.	H	α-helix	trans	-57.2	-45.6	174.9	176.7	0	0	0	0	111	L145 M305 L306 L311 V312 F313 I363 Y364	L145-V309 HydrophobicContact CD2-CG1 3.73Å; M305-V309 WeakPolarHBondContact O-CG2 3.43Å; M305-V309 PolarHBondContact O-N 3.49Å; M305-V309 VanDerWaalsContact O-N 3.1Å; L306-V309 PolarHBondContact O-N 3.29Å; V309-L311 PolarHBondContact O-N 2.84Å; V309-V312 PolarHBondContact O-N 2.97Å; V309-F313 WeakPolarHBondContact O-CB 3.3Å; V309-F313 PolarHBondContact O-N 2.74Å; V309-I363 HydrophobicContact CG2-CB 4.44Å; V309-I363 HydrophobicContact CG2-CD1 4.34Å; V309-I363 HydrophobicContact CG2-CG2 3.66Å; V309-Y364 HydrophobicContact CG2-CD1 4.47Å; V309-Y364 HydrophobicContact CG2-CE1 3.81Å
310	L	90.8	Very high	90.4	Very high	11 Å²	11	45 Å²	45	6%	0.058	22%	0.223	C	C	.	.	H	α-helix	trans	-61.3	-43.2	176.8	177.8	63	0	0	0	112.5	L236 M239 V240 Y243 L306 M307 V308 F313 A314	L236-L310 HydrophobicContact CD1-CD1 3.78Å; L236-L310 HydrophobicContact CD1-CG 4.29Å; M239-L310 HydrophobicContact CB-CD1 3.98Å; M239-L310 HydrophobicContact CB-CD2 3.8Å; M239-L310 HydrophobicContact CE-CD1 3.51Å; M239-L310 HydrophobicContact CG-CD1 4.46Å; M239-L310 HydrophobicContact SD-CD1 3.63Å; V240-L310 HydrophobicContact CG2-CD2 4.35Å; Y243-L310 HydrophobicContact CD2-CD2 3.52Å; Y243-L310 HydrophobicContact CE2-CB 4.5Å; Y243-L310 HydrophobicContact CE2-CD2 3.81Å; L306-L310 PolarHBondContact O-N 3.11Å; M307-L310 PolarHBondContact O-N 3.35Å; V308-L310 VanDerWaalsContact C-N 3.31Å; V308-L310 PolarHBondContact O-N 3.27Å; L310-F313 PolarHBondContact O-N 2.78Å; L310-A314 WeakPolarHBondContact O-CB 3.43Å; L310-A314 PolarHBondContact O-N 2.85Å
311	L	94.1	Very high	91	Very high	102 Å²	102	41.3 Å²	41.3	53%	0.534	21%	0.211	S	C	.	.	H	α-helix	trans	-64.6	-44	-179.9	-179.4	64	0	0	0	111.4	M307 V308 V309 A314 I315	M307-L311 WeakPolarHBondContact O-CB 3.25Å; M307-L311 PolarHBondContact O-N 3.26Å; V308-L311 PolarHBondContact O-N 3.02Å; V309-L311 PolarHBondContact O-N 2.84Å; L311-A314 PolarHBondContact O-N 2.65Å; L311-I315 HydrophobicContact CD1-CD1 3.93Å; L311-I315 HydrophobicContact CD1-CG1 4.34Å; L311-I315 HydrophobicContact CG-CD1 3.86Å; L311-I315 VanDerWaalsContact O-CG1 3.31Å; L311-I315 WeakPolarHBondContact O-CG1 3.2Å; L311-I315 PolarHBondContact O-N 3.27Å
312	V	95.4	Very high	91.6	Very high	36 Å²	36	40.5 Å²	40.5	22%	0.218	21%	0.211	C	C	.	.	H	α-helix	trans	-62.5	-45.2	176.6	172.9	0	0	0	0	110.4	V308 V309 A314 I315 C316 A359 I363	V308-V312 HydrophobicContact CG1-CG2 4.39Å; V308-V312 WeakPolarHBondContact O-CG2 3.46Å; V308-V312 PolarHBondContact O-N 3.35Å; V309-V312 PolarHBondContact O-N 2.97Å; V312-A314 PolarHBondContact O-N 3.49Å; V312-I315 PolarHBondContact O-N 3.41Å; V312-C316 WeakPolarHBondContact O-CB 3.28Å; V312-C316 PolarHBondContact O-N 2.99Å; V312-C316 PolarHBondContact O-SG 3.18Å; V312-C316 VanDerWaalsContact O-SG 3.35Å; V312-A359 HydrophobicContact CG1-CB 3.87Å; V312-I363 HydrophobicContact CB-CD1 4.06Å; V312-I363 HydrophobicContact CG1-CD1 4.22Å; V312-I363 HydrophobicContact CG2-CD1 3.88Å
313	F	92.6	Very high	92.4	Very high	2 Å²	2	39 Å²	39	1%	0.009	20%	0.201	C	C	.	.	H	α-helix	trans	-57	-48.3	174.1	178.8	-90.2	0	0	0	111.9	V142 L145 V309 L310 I315 C316 Y317 N356	V142-F313 HydrophobicContact CB-CE1 4.39Å; V142-F313 HydrophobicContact CB-CZ 3.9Å; V142-F313 HydrophobicContact CG2-CE1 4.09Å; V142-F313 HydrophobicContact CG2-CZ 4.11Å; L145-F313 HydrophobicContact CD1-CB 3.96Å; L145-F313 HydrophobicContact CD1-CD1 4.14Å; L145-F313 HydrophobicContact CD1-CD2 3.66Å; L145-F313 HydrophobicContact CD1-CE2 4.19Å; L145-F313 HydrophobicContact CD1-CG 3.64Å; V309-F313 WeakPolarHBondContact O-CB 3.3Å; V309-F313 PolarHBondContact O-N 2.74Å; L310-F313 PolarHBondContact O-N 2.78Å; F313-I315 PolarHBondContact O-N 2.96Å; F313-C316 PolarHBondContact O-N 3.41Å; F313-Y317 AromaticContact CD2-CD2 3.61Å; F313-Y317 HydrophobicContact CD2-CD2 3.61Å; F313-Y317 AromaticContact CD2-CE2 3.49Å; F313-Y317 HydrophobicContact CD2-CE2 3.49Å; F313-Y317 VanDerWaalsContact CD2-CE2 3.49Å; F313-Y317 HydrophobicContact CE1-CD2 4.44Å; F313-Y317 AromaticContact CE2-CD2 3.54Å; F313-Y317 HydrophobicContact CE2-CD2 3.54Å; F313-Y317 HydrophobicContact CE2-CE1 4.45Å; F313-Y317 AromaticContact CE2-CE2 3.32Å; F313-Y317 HydrophobicContact CE2-CE2 3.32Å; F313-Y317 HydrophobicContact CE2-CG 4.19Å; F313-Y317 AromaticContact CE2-CZ 3.82Å; F313-Y317 HydrophobicContact CG-CD2 4.11Å; F313-Y317 HydrophobicContact CG-CE2 4.41Å; F313-Y317 AromaticContact CZ-CD2 3.97Å; F313-Y317 HydrophobicContact CZ-CD2 3.97Å; F313-Y317 HydrophobicContact CZ-CE2 4.13Å; F313-Y317 HydrophobicContact CZ-CG 4.2Å; F313-Y317 WeakPolarHBondContact O-CB 3.32Å; F313-Y317 VanDerWaalsContact O-CD2 3.31Å; F313-Y317 WeakPolarHBondContact O-CD2 3.4Å; F313-Y317 PolarHBondContact O-N 3.31Å; F313-Y317 VanDerWaalsContact O-N 3.08Å; F313-N356 WeakPolarHBondContact CA-OD1 3.24Å
314	A	95.1	Very high	93	Very high	14 Å²	14	40.7 Å²	40.7	12%	0.116	21%	0.209	C	C	.	.	H	α-helix	trans	-59.5	-45.9	179.1	0	0	0	0	0	111.7	Y232 L236 L310 L311 V312 L318	Y232-A314 PolarHBondContact OH-O 3.26Å; Y232-A314 VanDerWaalsContact OH-O 3.04Å; L236-A314 HydrophobicContact CD1-CB 3.86Å; L236-A314 HydrophobicContact CD2-CB 4.13Å; L310-A314 WeakPolarHBondContact O-CB 3.43Å; L310-A314 PolarHBondContact O-N 2.85Å; L311-A314 PolarHBondContact O-N 2.65Å; V312-A314 PolarHBondContact O-N 3.49Å; A314-L318 VanDerWaalsContact O-CB 3.25Å; A314-L318 WeakPolarHBondContact O-CB 3.31Å; A314-L318 PolarHBondContact O-N 3.37Å; A314-L318 VanDerWaalsContact O-N 3.08Å
315	I	96.9	Very high	93.5	Very high	96 Å²	96	35.3 Å²	35.3	49%	0.492	19%	0.192	S	C	.	.	H	α-helix	trans	-66.8	-44.3	-179.7	-67.7	168.3	0	0	0	111.3	L311 V312 F313 Y317 L318 P319	L311-I315 HydrophobicContact CD1-CD1 3.93Å; L311-I315 HydrophobicContact CD1-CG1 4.34Å; L311-I315 HydrophobicContact CG-CD1 3.86Å; L311-I315 VanDerWaalsContact O-CG1 3.31Å; L311-I315 WeakPolarHBondContact O-CG1 3.2Å; L311-I315 PolarHBondContact O-N 3.27Å; V312-I315 PolarHBondContact O-N 3.41Å; F313-I315 PolarHBondContact O-N 2.96Å; I315-Y317 VanDerWaalsContact C-N 3.35Å; I315-Y317 PolarHBondContact O-N 3.38Å; I315-L318 PolarHBondContact O-N 2.93Å; I315-P319 VanDerWaalsContact O-CD 3.25Å; I315-P319 WeakPolarHBondContact O-CD 3.04Å
316	C	96.9	Very high	93.9	Very high	11 Å²	11	36.8 Å²	36.8	7%	0.074	20%	0.2	C	C	.	.	H	α-helix	trans	-68	-34.1	-176.2	-73.5	0	0	0	0	113.2	V312 F313 L352 N356	V312-C316 WeakPolarHBondContact O-CB 3.28Å; V312-C316 PolarHBondContact O-N 2.99Å; V312-C316 PolarHBondContact O-SG 3.18Å; V312-C316 VanDerWaalsContact O-SG 3.35Å; F313-C316 PolarHBondContact O-N 3.41Å; C316-L352 HydrophobicContact CB-CG 4.17Å; C316-N356 HydrophobicContact CB-CB 3.73Å
317	Y	96.1	Very high	94.3	Very high	13 Å²	13	40 Å²	40	5%	0.051	21%	0.214	C	C	.	.	H	α-helix	trans	-91.5	-13	-178.9	-78.2	-94.8	0	0	0	113.9	V138 F313 I315 I320 S321 V353 N356	V138-Y317 HydrophobicContact CB-CE1 4.3Å; V138-Y317 HydrophobicContact CG1-CD1 4.27Å; V138-Y317 HydrophobicContact CG1-CE1 3.75Å; V138-Y317 HydrophobicContact CG2-CE1 3.65Å; F313-Y317 AromaticContact CD2-CD2 3.61Å; F313-Y317 HydrophobicContact CD2-CD2 3.61Å; F313-Y317 AromaticContact CD2-CE2 3.49Å; F313-Y317 HydrophobicContact CD2-CE2 3.49Å; F313-Y317 VanDerWaalsContact CD2-CE2 3.49Å; F313-Y317 HydrophobicContact CE1-CD2 4.44Å; F313-Y317 AromaticContact CE2-CD2 3.54Å; F313-Y317 HydrophobicContact CE2-CD2 3.54Å; F313-Y317 HydrophobicContact CE2-CE1 4.45Å; F313-Y317 AromaticContact CE2-CE2 3.32Å; F313-Y317 HydrophobicContact CE2-CE2 3.32Å; F313-Y317 HydrophobicContact CE2-CG 4.19Å; F313-Y317 AromaticContact CE2-CZ 3.82Å; F313-Y317 HydrophobicContact CG-CD2 4.11Å; F313-Y317 HydrophobicContact CG-CE2 4.41Å; F313-Y317 AromaticContact CZ-CD2 3.97Å; F313-Y317 HydrophobicContact CZ-CD2 3.97Å; F313-Y317 HydrophobicContact CZ-CE2 4.13Å; F313-Y317 HydrophobicContact CZ-CG 4.2Å; F313-Y317 WeakPolarHBondContact O-CB 3.32Å; F313-Y317 VanDerWaalsContact O-CD2 3.31Å; F313-Y317 WeakPolarHBondContact O-CD2 3.4Å; F313-Y317 PolarHBondContact O-N 3.31Å; F313-Y317 VanDerWaalsContact O-N 3.08Å; I315-Y317 VanDerWaalsContact C-N 3.35Å; I315-Y317 PolarHBondContact O-N 3.38Å; Y317-I320 VanDerWaalsContact O-CG2 3.29Å; Y317-I320 WeakPolarHBondContact O-CG2 3.48Å; Y317-S321 VanDerWaalsContact O-CB 3.23Å; Y317-S321 WeakPolarHBondContact O-CB 3.48Å; Y317-S321 PolarHBondContact O-N 2.82Å; Y317-S321 VanDerWaalsContact O-N 3.1Å; Y317-S321 PolarHBondContact O-OG 3.12Å; Y317-V353 HydrophobicContact CD1-CG2 4.22Å; Y317-V353 HydrophobicContact CE1-CG1 3.81Å; Y317-V353 HydrophobicContact CE1-CG2 4.25Å; Y317-N356 HydrophobicContact CE2-CB 4.12Å
318	L	96.7	Very high	94.5	Very high	75 Å²	75	38.1 Å²	38.1	39%	0.393	20%	0.202	S	C	.	.	H	α-helix	trans	-60	-49.5	-178.4	-179.6	70.8	0	0	0	112.9	Y232 A314 I315 I320 S321 I322	Y232-L318 HydrophobicContact CE1-CD1 4.2Å; Y232-L318 WeakPolarHBondContact OH-CD1 3.47Å; A314-L318 VanDerWaalsContact O-CB 3.25Å; A314-L318 WeakPolarHBondContact O-CB 3.31Å; A314-L318 PolarHBondContact O-N 3.37Å; A314-L318 VanDerWaalsContact O-N 3.08Å; I315-L318 PolarHBondContact O-N 2.93Å; L318-I320 PolarHBondContact O-N 3.45Å; L318-S321 PolarHBondContact O-N 2.66Å; L318-I322 HydrophobicContact CD1-CD1 3.67Å; L318-I322 HydrophobicContact CD1-CG1 4.07Å; L318-I322 HydrophobicContact CD2-CD1 4.5Å; L318-I322 HydrophobicContact CG-CD1 3.81Å; L318-I322 HydrophobicContact CG-CG1 4.45Å; L318-I322 WeakPolarHBondContact O-CG1 3.31Å; L318-I322 PolarHBondContact O-N 3.49Å
319	P	97.2	Very high	94.5	Very high	29 Å²	29	36.6 Å²	36.6	19%	0.188	19%	0.192	C	C	.	.	H	α-helix	trans	-61.5	-49.5	-175.5	-26.6	38.6	0	0	0	112.3	I315 S321 I322 L323 S349 L352	I315-P319 VanDerWaalsContact O-CD 3.25Å; I315-P319 WeakPolarHBondContact O-CD 3.04Å; P319-S321 VanDerWaalsContact C-N 3.29Å; P319-S321 PolarHBondContact O-N 3.48Å; P319-I322 PolarHBondContact O-N 2.86Å; P319-L323 WeakPolarHBondContact O-CB 3.45Å; P319-L323 VanDerWaalsContact O-CG 3.3Å; P319-L323 WeakPolarHBondContact O-CG 3.25Å; P319-L323 PolarHBondContact O-N 3.14Å; P319-S349 WeakPolarHBondContact CB-OG 3.32Å; P319-L352 HydrophobicContact CG-CD2 3.78Å
320	I	96.2	Very high	94.6	Very high	17 Å²	17	43.2 Å²	43.2	9%	0.087	22%	0.221	C	C	.	.	H	α-helix	trans	-63.7	-36.9	179.6	-167.8	57.7	0	0	0	111.9	Y317 L318 L323 N324 F346 V353	Y317-I320 VanDerWaalsContact O-CG2 3.29Å; Y317-I320 WeakPolarHBondContact O-CG2 3.48Å; L318-I320 PolarHBondContact O-N 3.45Å; I320-L323 PolarHBondContact O-N 3.23Å; I320-N324 WeakPolarHBondContact O-CB 3.37Å; I320-N324 VanDerWaalsContact O-CG 3.27Å; I320-N324 PolarHBondContact O-N 2.85Å; I320-N324 PolarHBondContact O-ND2 3.46Å; I320-F346 HydrophobicContact CD1-CD1 4.22Å; I320-F346 HydrophobicContact CD1-CE1 4.45Å; I320-V353 HydrophobicContact CB-CG2 4.16Å; I320-V353 HydrophobicContact CG2-CG2 3.54Å
321	S	95.4	Very high	94.5	Very high	13 Å²	13	44 Å²	44	9%	0.091	23%	0.233	C	C	.	.	H	α-helix	trans	-65.7	-43.6	179.4	-62.8	0	0	0	0	111.2	Y317 L318 P319 V325	Y317-S321 VanDerWaalsContact O-CB 3.23Å; Y317-S321 WeakPolarHBondContact O-CB 3.48Å; Y317-S321 PolarHBondContact O-N 2.82Å; Y317-S321 VanDerWaalsContact O-N 3.1Å; Y317-S321 PolarHBondContact O-OG 3.12Å; L318-S321 PolarHBondContact O-N 2.66Å; P319-S321 VanDerWaalsContact C-N 3.29Å; P319-S321 PolarHBondContact O-N 3.48Å; S321-V325 WeakPolarHBondContact O-CG2 3.27Å; S321-V325 PolarHBondContact O-N 2.89Å
322	I	95.6	Very high	94.1	Very high	79 Å²	79	44.5 Å²	44.5	41%	0.405	23%	0.233	S	C	.	.	H	α-helix	trans	-65.6	-49.5	175.8	-68.8	175.7	0	0	0	110.1	L318 P319 N324 V325 L326	L318-I322 HydrophobicContact CD1-CD1 3.67Å; L318-I322 HydrophobicContact CD1-CG1 4.07Å; L318-I322 HydrophobicContact CD2-CD1 4.5Å; L318-I322 HydrophobicContact CG-CD1 3.81Å; L318-I322 HydrophobicContact CG-CG1 4.45Å; L318-I322 WeakPolarHBondContact O-CG1 3.31Å; L318-I322 PolarHBondContact O-N 3.49Å; P319-I322 PolarHBondContact O-N 2.86Å; I322-N324 VanDerWaalsContact C-N 3.33Å; I322-N324 PolarHBondContact O-N 3.38Å; I322-V325 PolarHBondContact O-N 2.85Å; I322-V325 VanDerWaalsContact O-N 3.14Å; I322-L326 HydrophobicContact CG2-CD1 3.63Å; I322-L326 HydrophobicContact CG2-CG 4Å; I322-L326 VanDerWaalsContact O-CG 3.32Å; I322-L326 WeakPolarHBondContact O-CG 3.41Å; I322-L326 PolarHBondContact O-N 3.5Å
323	L	95.4	Very high	93.6	Very high	18 Å²	18	45.3 Å²	45.3	9%	0.094	23%	0.234	C	C	.	.	H	α-helix	trans	-59.8	-41.4	-178.3	-72.6	175	0	0	0	112.4	P319 I320 V325 L326 K327 F333 W345 F346 S349	P319-L323 WeakPolarHBondContact O-CB 3.45Å; P319-L323 VanDerWaalsContact O-CG 3.3Å; P319-L323 WeakPolarHBondContact O-CG 3.25Å; P319-L323 PolarHBondContact O-N 3.14Å; I320-L323 PolarHBondContact O-N 3.23Å; L323-V325 PolarHBondContact O-N 3.28Å; L323-L326 PolarHBondContact O-N 3.36Å; L323-K327 VanDerWaalsContact O-CB 3.25Å; L323-K327 WeakPolarHBondContact O-CB 3.47Å; L323-K327 PolarHBondContact O-N 2.93Å; L323-F333 HydrophobicContact CD2-CE2 4.13Å; L323-F333 HydrophobicContact CD2-CZ 4Å; L323-W345 HydrophobicContact CD1-CB 4.13Å; L323-W345 WeakPolarHBondContact CD1-O 3.37Å; L323-W345 HydrophobicContact CD2-CB 4.46Å; L323-F346 HydrophobicContact CB-CD1 4.46Å; L323-F346 HydrophobicContact CB-CE1 3.87Å; L323-F346 HydrophobicContact CB-CE2 4.3Å; L323-F346 HydrophobicContact CB-CZ 3.77Å; L323-F346 HydrophobicContact CD1-CD1 4.39Å; L323-F346 HydrophobicContact CD1-CD2 4.42Å; L323-F346 HydrophobicContact CD1-CG 4.3Å; L323-F346 HydrophobicContact CD2-CE2 4.45Å; L323-S349 WeakPolarHBondContact CD1-OG 3.35Å
324	N	94.3	Very high	92.7	Very high	41 Å²	41	50.1 Å²	50.1	22%	0.219	26%	0.264	C	S	.	.	H	α-helix	trans	-62.9	-42.6	175.9	-76.6	-15.6	0	0	0	111.9	I320 I322 R328	I320-N324 WeakPolarHBondContact O-CB 3.37Å; I320-N324 VanDerWaalsContact O-CG 3.27Å; I320-N324 PolarHBondContact O-N 2.85Å; I320-N324 PolarHBondContact O-ND2 3.46Å; I322-N324 VanDerWaalsContact C-N 3.33Å; I322-N324 PolarHBondContact O-N 3.38Å; N324-R328 VanDerWaalsContact O-CB 3.23Å; N324-R328 WeakPolarHBondContact O-CB 3.25Å; N324-R328 WeakPolarHBondContact O-CG 3.21Å; N324-R328 PolarHBondContact O-N 3.28Å
325	V	95.2	Very high	91.8	Very high	27 Å²	27	58 Å²	58	16%	0.164	30%	0.298	C	S	.	.	H	α-helix	trans	-64.9	-46.7	175.8	170.9	0	0	0	0	111	F228 S321 I322 L323 K327 V329 F330	F228-V325 HydrophobicContact CB-CG2 3.96Å; F228-V325 HydrophobicContact CD1-CG2 4.37Å; F228-V325 HydrophobicContact CD2-CG2 4.12Å; F228-V325 HydrophobicContact CG-CG2 3.9Å; S321-V325 WeakPolarHBondContact O-CG2 3.27Å; S321-V325 PolarHBondContact O-N 2.89Å; I322-V325 PolarHBondContact O-N 2.85Å; I322-V325 VanDerWaalsContact O-N 3.14Å; L323-V325 PolarHBondContact O-N 3.28Å; V325-K327 PolarHBondContact O-N 2.98Å; V325-V329 HydrophobicContact CG1-CB 4.23Å; V325-V329 HydrophobicContact CG1-CG2 4.14Å; V325-V329 WeakPolarHBondContact O-CA 3.35Å; V325-V329 WeakPolarHBondContact O-CB 3.23Å; V325-V329 PolarHBondContact O-N 3.33Å; V325-F330 HydrophobicContact CG1-CD2 3.97Å; V325-F330 HydrophobicContact CG1-CE2 3.66Å; V325-F330 PolarHBondContact O-N 2.89Å
326	L	94.1	Very high	91.1	Very high	42 Å²	42	55.5 Å²	55.5	22%	0.22	29%	0.287	C	S	.	.	H	α-helix	trans	-61.2	-43	178.5	-67.8	179	0	0	0	112.2	I322 L323 F330 G331 M332 F333	I322-L326 HydrophobicContact CG2-CD1 3.63Å; I322-L326 HydrophobicContact CG2-CG 4Å; I322-L326 VanDerWaalsContact O-CG 3.32Å; I322-L326 WeakPolarHBondContact O-CG 3.41Å; I322-L326 PolarHBondContact O-N 3.5Å; L323-L326 PolarHBondContact O-N 3.36Å; L326-F330 HydrophobicContact CD2-CD2 4.14Å; L326-G331 PolarHBondContact O-N 2.88Å; L326-G331 VanDerWaalsContact O-N 3.15Å; L326-M332 HydrophobicContact CB-CE 4.36Å; L326-M332 HydrophobicContact CD1-CE 3.99Å; L326-M332 HydrophobicContact CD2-CE 3.86Å; L326-M332 HydrophobicContact CD2-CG 4.49Å; L326-M332 HydrophobicContact CD2-SD 4.3Å; L326-M332 HydrophobicContact CG-CE 4.27Å; L326-M332 PolarHBondContact O-N 2.92Å; L326-M332 VanDerWaalsContact O-N 3.1Å; L326-F333 HydrophobicContact CB-CE2 3.85Å; L326-F333 HydrophobicContact CB-CZ 4.2Å; L326-F333 HydrophobicContact CD1-CZ 4.36Å
327	K	92.2	Very high	90.1	Very high	74 Å²	74	63.3 Å²	63.3	32%	0.322	33%	0.328	S	S	.	.	H	α-helix	trans	-68.3	-53	178.1	-175.4	177.2	175.7	-178.6	0	111.9	L323 V325 G331 F333 F346	L323-K327 VanDerWaalsContact O-CB 3.25Å; L323-K327 WeakPolarHBondContact O-CB 3.47Å; L323-K327 PolarHBondContact O-N 2.93Å; V325-K327 PolarHBondContact O-N 2.98Å; K327-G331 WeakPolarHBondContact O-CA 3.27Å; K327-G331 PolarHBondContact O-N 3.35Å; K327-F333 HydrophobicContact CB-CD2 3.84Å; K327-F333 HydrophobicContact CB-CE2 4.33Å; K327-F333 HydrophobicContact CG-CD2 4.36Å; K327-F346 HydrophobicContact CB-CZ 4.05Å; K327-F346 HydrophobicContact CD-CE1 4.29Å; K327-F346 HydrophobicContact CD-CE2 4.28Å; K327-F346 HydrophobicContact CD-CZ 3.65Å; K327-F346 HydrophobicContact CG-CZ 4.41Å
328	R	92.5	Very high	89.6	Confident	49 Å²	49	66.5 Å²	66.5	19%	0.185	35%	0.346	C	S	.	.	H	α-helix	trans	-93.8	-28.1	-164.3	-58.1	-71.4	-169.9	-168.5	0.6	113.9	D211 E212 H224 N324	D211-R328 IonicContact OD1-CZ 2.66Å; D211-R328 IonicContact OD1-NH1 3.68Å; D211-R328 PolarHBondContact OD1-NH1 2.84Å; D211-R328 IonicContact OD1-NH2 3.48Å; D211-R328 PolarHBondContact OD1-NH2 2.86Å; D211-R328 IonicContact OD2-NH1 3.49Å; D211-R328 PolarHBondContact OD2-NH1 2.93Å; D211-R328 IonicContact OD2-NH2 3.45Å; E212-R328 IonicContact OE2-NE 3.93Å; H224-R328 HydrophobicContact CB-CB 3.96Å; H224-R328 WeakPolarHBondContact CD2-CB 3.23Å; N324-R328 VanDerWaalsContact O-CB 3.23Å; N324-R328 WeakPolarHBondContact O-CB 3.25Å; N324-R328 WeakPolarHBondContact O-CG 3.21Å; N324-R328 PolarHBondContact O-N 3.28Å
329	V	92.8	Very high	88.9	Confident	18 Å²	18	72.1 Å²	72.1	11%	0.109	36%	0.362	C	S	.	.	T	Hydrogen-bonded Turn	trans	-94	-49.1	-179.7	-174.4	0	0	0	0	110.9	K221 H224 I225 V325	K221-V329 WeakPolarHBondContact CE-O 3.34Å; H224-V329 HydrophobicContact CB-CG2 4.07Å; I225-V329 HydrophobicContact CD1-CG1 3.89Å; I225-V329 HydrophobicContact CG1-CG1 4Å; I225-V329 HydrophobicContact CG1-CG2 3.82Å; V325-V329 HydrophobicContact CG1-CB 4.23Å; V325-V329 HydrophobicContact CG1-CG2 4.14Å; V325-V329 WeakPolarHBondContact O-CA 3.35Å; V325-V329 WeakPolarHBondContact O-CB 3.23Å; V325-V329 PolarHBondContact O-N 3.33Å
330	F	91.6	Very high	88.4	Confident	140 Å²	140	76.7 Å²	76.7	61%	0.614	38%	0.381	S	S	*	.	S	Bend	trans	-95.4	-13.8	-174.1	-64	-69.5	0	0	0	114.3	V325 L326 M332	V325-F330 HydrophobicContact CG1-CD2 3.97Å; V325-F330 HydrophobicContact CG1-CE2 3.66Å; V325-F330 PolarHBondContact O-N 2.89Å; L326-F330 HydrophobicContact CD2-CD2 4.14Å; F330-M332 VanDerWaalsContact C-N 3.29Å; F330-M332 HydrophobicContact CB-CG 3.89Å; F330-M332 PolarHBondContact O-N 3.23Å
331	G	87.6	Confident	88	Confident	29 Å²	29	78.9 Å²	78.9	30%	0.299	40%	0.395	S	S	.	.			trans	67.6	24.4	177.8	0	0	0	0	0	114.3	L326 K327 F333 T334	L326-G331 PolarHBondContact O-N 2.88Å; L326-G331 VanDerWaalsContact O-N 3.15Å; K327-G331 WeakPolarHBondContact O-CA 3.27Å; K327-G331 PolarHBondContact O-N 3.35Å; G331-F333 VanDerWaalsContact C-N 3.29Å; G331-F333 PolarHBondContact O-N 3.05Å; G331-T334 PolarHBondContact O-OG1 3.48Å; G331-T334 VanDerWaalsContact O-OG1 3.13Å
332	M	85.6	Confident	87.8	Confident	111 Å²	111	79.4 Å²	79.4	55%	0.547	40%	0.398	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67	-22.5	-168.6	-65.8	-133.9	-48	0	0	115.3	L326 F330	L326-M332 HydrophobicContact CB-CE 4.36Å; L326-M332 HydrophobicContact CD1-CE 3.99Å; L326-M332 HydrophobicContact CD2-CE 3.86Å; L326-M332 HydrophobicContact CD2-CG 4.49Å; L326-M332 HydrophobicContact CD2-SD 4.3Å; L326-M332 HydrophobicContact CG-CE 4.27Å; L326-M332 PolarHBondContact O-N 2.92Å; L326-M332 VanDerWaalsContact O-N 3.1Å; F330-M332 VanDerWaalsContact C-N 3.29Å; F330-M332 HydrophobicContact CB-CG 3.89Å; F330-M332 PolarHBondContact O-N 3.23Å
333	F	85.2	Confident	87.4	Confident	53 Å²	53	78.2 Å²	78.2	23%	0.232	39%	0.389	C	S	.	.	T	Hydrogen-bonded Turn	trans	-107.9	17.5	-171.4	-53	-58.3	0	0	0	113.8	L323 L326 K327 G331 V342 F346	L323-F333 HydrophobicContact CD2-CE2 4.13Å; L323-F333 HydrophobicContact CD2-CZ 4Å; L326-F333 HydrophobicContact CB-CE2 3.85Å; L326-F333 HydrophobicContact CB-CZ 4.2Å; L326-F333 HydrophobicContact CD1-CZ 4.36Å; K327-F333 HydrophobicContact CB-CD2 3.84Å; K327-F333 HydrophobicContact CB-CE2 4.33Å; K327-F333 HydrophobicContact CG-CD2 4.36Å; G331-F333 VanDerWaalsContact C-N 3.29Å; G331-F333 PolarHBondContact O-N 3.05Å; F333-V342 HydrophobicContact CB-CG1 4.2Å; F333-V342 HydrophobicContact CD1-CB 4.42Å; F333-V342 HydrophobicContact CD1-CG1 3.86Å; F333-V342 HydrophobicContact CD1-CG2 3.6Å; F333-V342 HydrophobicContact CD2-CG1 4.25Å; F333-V342 HydrophobicContact CE1-CG1 4.26Å; F333-V342 HydrophobicContact CE1-CG2 3.87Å; F333-V342 HydrophobicContact CG-CG1 3.85Å; F333-V342 HydrophobicContact CG-CG2 4.39Å; F333-F346 HydrophobicContact CD2-CE2 4.18Å; F333-F346 HydrophobicContact CE2-CE2 4.21Å
334	T	75.2	Confident	87.2	Confident	103 Å²	103	79.4 Å²	79.4	63%	0.632	40%	0.401	S	S	*	.	S	Bend	trans	-75.4	-34.4	-177.8	50	0	0	0	0	113.4	G331	G331-T334 PolarHBondContact O-OG1 3.48Å; G331-T334 VanDerWaalsContact O-OG1 3.13Å
335	H	76	Confident	87.1	Confident	180 Å²	180	84.3 Å²	84.3	83%	0.833	42%	0.416	S	S	*	.	S	Bend	trans	-133.5	54.5	-178.6	-62.7	-69.6	0	0	0	111.5
336	T	80.8	Confident	87.1	Confident	44 Å²	44	84.1 Å²	84.1	27%	0.27	41%	0.413	S	S	.	.			trans	-94.3	133.2	174.4	-176.4	0	0	0	0	110.7	D338 R339 V342	T336-D338 PolarHBondContact O-N 3.44Å; T336-D338 PolarHBondContact OG1-N 2.87Å; T336-R339 HydrophobicContact CG2-CG 4.11Å; T336-R339 WeakPolarHBondContact O-CG 3.32Å; T336-V342 HydrophobicContact CG2-CG2 4.07Å
337	D	76	Confident	87.1	Confident	175 Å²	175	82.5 Å²	82.5	94%	0.936	41%	0.405	S	S	*	.	S	Bend	trans	-70.9	-18.9	172	-63.8	-36	0	0	0	111.6
338	D	85.4	Confident	87.2	Confident	80 Å²	80	83.3 Å²	83.3	43%	0.428	41%	0.409	S	S	.	.			trans	-106.3	58.9	-176.7	-169.2	8.4	0	0	0	111.9	T336 E340 T341 V342	T336-D338 PolarHBondContact O-N 3.44Å; T336-D338 PolarHBondContact OG1-N 2.87Å; D338-E340 VanDerWaalsContact C-N 3.27Å; D338-E340 PolarHBondContact O-N 3.49Å; D338-T341 PolarHBondContact O-N 2.91Å; D338-T341 WeakPolarHBondContact OD1-CB 3.25Å; D338-T341 PolarHBondContact OD1-N 3.3Å; D338-T341 PolarHBondContact OD1-OG1 3.2Å; D338-T341 WeakPolarHBondContact OD2-CB 3.33Å; D338-T341 PolarHBondContact OD2-OG1 2.63Å; D338-V342 PolarHBondContact O-N 3.33Å
339	R	83.6	Confident	87.4	Confident	192 Å²	192	81 Å²	81	73%	0.725	40%	0.4	S	S	*	.	H	α-helix	trans	-63.4	-33.2	-179.7	-64	-178.3	72.1	-178.4	-0.4	112.4	T336 V342 Y343	T336-R339 HydrophobicContact CG2-CG 4.11Å; T336-R339 WeakPolarHBondContact O-CG 3.32Å; R339-V342 PolarHBondContact O-N 2.92Å; R339-Y343 WeakPolarHBondContact O-CB 3.3Å; R339-Y343 PolarHBondContact O-N 3.47Å
340	E	84.8	Confident	87.6	Confident	126 Å²	126	82 Å²	82	59%	0.589	40%	0.404	S	S	*	.	H	α-helix	trans	-63.3	-46.8	179.8	-64.9	-162.2	139.3	0	0	111.5	K51 D338 V342 Y343 A344	K51-E340 IonicContact NZ-OE1 2.81Å; K51-E340 PolarHBondContact NZ-OE1 3.05Å; D338-E340 VanDerWaalsContact C-N 3.27Å; D338-E340 PolarHBondContact O-N 3.49Å; E340-V342 PolarHBondContact O-N 3.4Å; E340-Y343 PolarHBondContact O-N 3.49Å; E340-A344 PolarHBondContact O-N 3.48Å
341	T	88.2	Confident	87.8	Confident	62 Å²	62	78.7 Å²	78.7	38%	0.38	39%	0.387	S	S	.	.	H	α-helix	trans	-65.7	-41.5	178.8	-61.2	0	0	0	0	111.8	D338 Y343 A344 W345	D338-T341 PolarHBondContact O-N 2.91Å; D338-T341 WeakPolarHBondContact OD1-CB 3.25Å; D338-T341 PolarHBondContact OD1-N 3.3Å; D338-T341 PolarHBondContact OD1-OG1 3.2Å; D338-T341 WeakPolarHBondContact OD2-CB 3.33Å; D338-T341 PolarHBondContact OD2-OG1 2.63Å; T341-Y343 VanDerWaalsContact C-N 3.32Å; T341-Y343 PolarHBondContact O-N 3.06Å; T341-A344 PolarHBondContact O-N 3.4Å; T341-W345 PolarHBondContact O-N 3.11Å
342	V	90.9	Very high	88.3	Confident	25 Å²	25	78.6 Å²	78.6	15%	0.152	38%	0.38	C	S	.	.	H	α-helix	trans	-61	-44.6	176.3	173	0	0	0	0	110.8	F333 T336 D338 R339 E340 W345 F346	F333-V342 HydrophobicContact CB-CG1 4.2Å; F333-V342 HydrophobicContact CD1-CB 4.42Å; F333-V342 HydrophobicContact CD1-CG1 3.86Å; F333-V342 HydrophobicContact CD1-CG2 3.6Å; F333-V342 HydrophobicContact CD2-CG1 4.25Å; F333-V342 HydrophobicContact CE1-CG1 4.26Å; F333-V342 HydrophobicContact CE1-CG2 3.87Å; F333-V342 HydrophobicContact CG-CG1 3.85Å; F333-V342 HydrophobicContact CG-CG2 4.39Å; T336-V342 HydrophobicContact CG2-CG2 4.07Å; D338-V342 PolarHBondContact O-N 3.33Å; R339-V342 PolarHBondContact O-N 2.92Å; E340-V342 PolarHBondContact O-N 3.4Å; V342-W345 PolarHBondContact O-N 3.5Å; V342-F346 HydrophobicContact CG1-CD2 3.91Å; V342-F346 HydrophobicContact CG1-CE2 3.9Å; V342-F346 WeakPolarHBondContact O-CD2 3.19Å; V342-F346 PolarHBondContact O-N 2.88Å; V342-F346 VanDerWaalsContact O-N 3.09Å
343	Y	89	Confident	88.9	Confident	54 Å²	54	73.7 Å²	73.7	21%	0.212	36%	0.356	C	S	.	.	H	α-helix	trans	-60.6	-45.9	177.1	-170.5	-101.8	0	0	0	111.8	V114 D115 E118 R339 E340 T341 W345 F346 T347	V114-Y343 PolarHBondContact O-OH 2.88Å; V114-Y343 VanDerWaalsContact O-OH 3.09Å; D115-Y343 WeakPolarHBondContact CA-OH 3.44Å; D115-Y343 VanDerWaalsContact O-CE1 3.24Å; D115-Y343 WeakPolarHBondContact O-CE1 3.27Å; D115-Y343 PolarHBondContact O-OH 3.47Å; E118-Y343 HydrophobicContact CG-CE1 4.16Å; E118-Y343 HydrophobicContact CG-CE2 3.87Å; E118-Y343 VanDerWaalsContact CG-OH 3.28Å; E118-Y343 WeakPolarHBondContact CG-OH 3.41Å; R339-Y343 WeakPolarHBondContact O-CB 3.3Å; R339-Y343 PolarHBondContact O-N 3.47Å; E340-Y343 PolarHBondContact O-N 3.49Å; T341-Y343 VanDerWaalsContact C-N 3.32Å; T341-Y343 PolarHBondContact O-N 3.06Å; Y343-W345 VanDerWaalsContact C-N 3.28Å; Y343-W345 PolarHBondContact O-N 3.39Å; Y343-F346 PolarHBondContact O-N 2.82Å; Y343-F346 VanDerWaalsContact O-N 3.08Å; Y343-T347 WeakPolarHBondContact O-CB 3.42Å; Y343-T347 PolarHBondContact O-N 3.43Å; Y343-T347 PolarHBondContact O-OG1 3.45Å; Y343-T347 VanDerWaalsContact O-OG1 3.12Å
344	A	90.4	Very high	89.4	Confident	43 Å²	43	71.3 Å²	71.3	36%	0.355	35%	0.346	S	S	.	.	H	α-helix	trans	-56.6	-39.8	175.7	0	0	0	0	0	112.7	E340 T341 F348	E340-A344 PolarHBondContact O-N 3.48Å; T341-A344 PolarHBondContact O-N 3.4Å; A344-F348 VanDerWaalsContact O-CB 3.29Å; A344-F348 WeakPolarHBondContact O-CB 3.45Å; A344-F348 PolarHBondContact O-N 3.01Å
345	W	93.1	Very high	90.5	Very high	143 Å²	143	67.2 Å²	67.2	54%	0.542	32%	0.322	S	S	.	.	H	α-helix	trans	-65.6	-41	174.8	-84.2	108.8	0	0	0	113.3	L323 T341 V342 Y343 F348 S349	L323-W345 HydrophobicContact CD1-CB 4.13Å; L323-W345 WeakPolarHBondContact CD1-O 3.37Å; L323-W345 HydrophobicContact CD2-CB 4.46Å; T341-W345 PolarHBondContact O-N 3.11Å; V342-W345 PolarHBondContact O-N 3.5Å; Y343-W345 VanDerWaalsContact C-N 3.28Å; Y343-W345 PolarHBondContact O-N 3.39Å; W345-F348 HydrophobicContact CE3-CD1 4.43Å; W345-F348 HydrophobicContact CZ3-CD1 4.44Å; W345-S349 VanDerWaalsContact O-CB 3.27Å; W345-S349 WeakPolarHBondContact O-CB 3.44Å; W345-S349 PolarHBondContact O-N 2.88Å; W345-S349 PolarHBondContact O-OG 2.66Å
346	F	94.1	Very high	91.5	Very high	23 Å²	23	58.7 Å²	58.7	10%	0.101	28%	0.283	C	S	.	.	H	α-helix	trans	-63.1	-49.4	175.1	-90.8	-81.8	0	0	0	111.1	I320 L323 K327 F333 V342 Y343 F348 S349 H350	I320-F346 HydrophobicContact CD1-CD1 4.22Å; I320-F346 HydrophobicContact CD1-CE1 4.45Å; L323-F346 HydrophobicContact CB-CD1 4.46Å; L323-F346 HydrophobicContact CB-CE1 3.87Å; L323-F346 HydrophobicContact CB-CE2 4.3Å; L323-F346 HydrophobicContact CB-CZ 3.77Å; L323-F346 HydrophobicContact CD1-CD1 4.39Å; L323-F346 HydrophobicContact CD1-CD2 4.42Å; L323-F346 HydrophobicContact CD1-CG 4.3Å; L323-F346 HydrophobicContact CD2-CE2 4.45Å; K327-F346 HydrophobicContact CB-CZ 4.05Å; K327-F346 HydrophobicContact CD-CE1 4.29Å; K327-F346 HydrophobicContact CD-CE2 4.28Å; K327-F346 HydrophobicContact CD-CZ 3.65Å; K327-F346 HydrophobicContact CG-CZ 4.41Å; F333-F346 HydrophobicContact CD2-CE2 4.18Å; F333-F346 HydrophobicContact CE2-CE2 4.21Å; V342-F346 HydrophobicContact CG1-CD2 3.91Å; V342-F346 HydrophobicContact CG1-CE2 3.9Å; V342-F346 WeakPolarHBondContact O-CD2 3.19Å; V342-F346 PolarHBondContact O-N 2.88Å; V342-F346 VanDerWaalsContact O-N 3.09Å; Y343-F346 PolarHBondContact O-N 2.82Å; Y343-F346 VanDerWaalsContact O-N 3.08Å; F346-F348 PolarHBondContact O-N 3.21Å; F346-S349 CarbonylContact O-C 3.58Å; F346-S349 WeakPolarHBondContact O-CA 3.43Å; F346-S349 WeakPolarHBondContact O-CB 3.42Å; F346-S349 PolarHBondContact O-N 3.09Å; F346-H350 PolarHBondContact O-N 2.9Å
347	T	93.4	Very high	92.3	Very high	8 Å²	8	56.7 Å²	56.7	5%	0.049	27%	0.27	C	S	.	.	H	α-helix	trans	-61.3	-44.1	179.8	-63.1	0	0	0	0	112.5	L57 D115 Y343 S349 H350 W351	L57-T347 HydrophobicContact CD1-CG2 3.78Å; L57-T347 HydrophobicContact CD2-CG2 3.1Å; L57-T347 HydrophobicContact CG-CG2 4.04Å; D115-T347 HydrophobicContact CB-CG2 3.84Å; Y343-T347 WeakPolarHBondContact O-CB 3.42Å; Y343-T347 PolarHBondContact O-N 3.43Å; Y343-T347 PolarHBondContact O-OG1 3.45Å; Y343-T347 VanDerWaalsContact O-OG1 3.12Å; T347-S349 VanDerWaalsContact C-N 3.31Å; T347-S349 PolarHBondContact O-N 3.26Å; T347-H350 PolarHBondContact O-N 3.12Å; T347-W351 PolarHBondContact O-N 3Å
348	F	94.9	Very high	93.3	Very high	92 Å²	92	48.7 Å²	48.7	40%	0.404	23%	0.229	S	C	.	.	H	α-helix	trans	-60.9	-40.9	172.3	173.8	-104.2	0	0	0	111.9	A344 W345 F346 W351 L352	A344-F348 VanDerWaalsContact O-CB 3.29Å; A344-F348 WeakPolarHBondContact O-CB 3.45Å; A344-F348 PolarHBondContact O-N 3.01Å; W345-F348 HydrophobicContact CE3-CD1 4.43Å; W345-F348 HydrophobicContact CZ3-CD1 4.44Å; F346-F348 PolarHBondContact O-N 3.21Å; F348-W351 HydrophobicContact CD2-CE3 4.11Å; F348-W351 HydrophobicContact CD2-CZ3 4.46Å; F348-W351 AromaticContact CE2-CE3 3.96Å; F348-W351 HydrophobicContact CE2-CE3 3.96Å; F348-W351 AromaticContact CE2-CZ3 3.88Å; F348-W351 HydrophobicContact CE2-CZ3 3.88Å; F348-W351 PolarHBondContact O-N 3.47Å; F348-L352 HydrophobicContact CE1-CD2 4.36Å; F348-L352 WeakPolarHBondContact O-CB 3.39Å; F348-L352 PolarHBondContact O-N 2.92Å
349	S	97	Very high	93.8	Very high	0 Å²	0	45.9 Å²	45.9	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-68	-38.9	179.4	-59.8	0	0	0	0	112.3	P319 L323 W345 F346 T347 L352 V353	P319-S349 WeakPolarHBondContact CB-OG 3.32Å; L323-S349 WeakPolarHBondContact CD1-OG 3.35Å; W345-S349 VanDerWaalsContact O-CB 3.27Å; W345-S349 WeakPolarHBondContact O-CB 3.44Å; W345-S349 PolarHBondContact O-N 2.88Å; W345-S349 PolarHBondContact O-OG 2.66Å; F346-S349 CarbonylContact O-C 3.58Å; F346-S349 WeakPolarHBondContact O-CA 3.43Å; F346-S349 WeakPolarHBondContact O-CB 3.42Å; F346-S349 PolarHBondContact O-N 3.09Å; T347-S349 VanDerWaalsContact C-N 3.31Å; T347-S349 PolarHBondContact O-N 3.26Å; S349-L352 PolarHBondContact O-N 2.67Å; S349-V353 WeakPolarHBondContact O-CG2 3.49Å; S349-V353 PolarHBondContact O-N 3.4Å; S349-V353 VanDerWaalsContact O-N 3.12Å
350	H	96.4	Very high	94.3	Very high	40 Å²	40	36.8 Å²	36.8	19%	0.185	18%	0.182	C	C	.	.	H	α-helix	trans	-60.6	-50	171.9	-67.4	162.7	0	0	0	111	Y61 T111 D115 F346 T347 L352 V353 Y354	Y61-H350 WeakPolarHBondContact OH-CB 3.47Å; T111-H350 HydrophobicContact CG2-CB 3.93Å; D115-H350 IonicContact OD1-CE1 2.9Å; D115-H350 IonicContact OD1-ND1 2.74Å; D115-H350 PolarHBondContact OD1-ND1 3.43Å; D115-H350 IonicContact OD2-CG 3.49Å; D115-H350 IonicContact OD2-ND1 3.72Å; D115-H350 PolarHBondContact OD2-ND1 2.84Å; F346-H350 PolarHBondContact O-N 2.9Å; T347-H350 PolarHBondContact O-N 3.12Å; H350-L352 VanDerWaalsContact C-N 3.27Å; H350-L352 PolarHBondContact O-N 3.42Å; H350-V353 WeakPolarHBondContact O-CB 3.35Å; H350-V353 PolarHBondContact O-N 3.06Å; H350-Y354 WeakPolarHBondContact O-CD2 3.24Å; H350-Y354 PolarHBondContact O-N 3.39Å
351	W	97.1	Very high	94.8	Very high	69 Å²	69	31.1 Å²	31.1	26%	0.261	16%	0.156	S	C	.	.	H	α-helix	trans	-56.2	-43.2	176.2	173.1	81.2	0	0	0	111.8	L57 G60 Y61 V64 T347 F348 V353 Y354 A355	L57-W351 HydrophobicContact CD1-CB 4.24Å; G60-W351 VanDerWaalsContact C-NE1 3.31Å; G60-W351 PolarHBondContact O-NE1 3Å; Y61-W351 AromaticContact CD2-CD1 3.94Å; Y61-W351 HydrophobicContact CE2-CB 3.95Å; Y61-W351 HydrophobicContact CE2-CG 4.49Å; Y61-W351 PolarHBondContact OH-N 2.9Å; V64-W351 HydrophobicContact CG2-CZ2 4.28Å; T347-W351 PolarHBondContact O-N 3Å; F348-W351 HydrophobicContact CD2-CE3 4.11Å; F348-W351 HydrophobicContact CD2-CZ3 4.46Å; F348-W351 AromaticContact CE2-CE3 3.96Å; F348-W351 HydrophobicContact CE2-CE3 3.96Å; F348-W351 AromaticContact CE2-CZ3 3.88Å; F348-W351 HydrophobicContact CE2-CZ3 3.88Å; F348-W351 PolarHBondContact O-N 3.47Å; W351-V353 VanDerWaalsContact C-N 3.33Å; W351-V353 PolarHBondContact O-N 2.9Å; W351-Y354 PolarHBondContact O-N 3.1Å; W351-A355 HydrophobicContact CZ2-CB 4.45Å; W351-A355 PolarHBondContact O-N 2.74Å
352	L	97.6	Very high	95.2	Very high	27 Å²	27	31.9 Å²	31.9	14%	0.141	16%	0.157	C	C	.	.	H	α-helix	trans	-65.5	-33.9	-178.9	-167.4	68.2	0	0	0	113	C316 P319 F348 S349 H350 A355 N356	C316-L352 HydrophobicContact CB-CG 4.17Å; P319-L352 HydrophobicContact CG-CD2 3.78Å; F348-L352 HydrophobicContact CE1-CD2 4.36Å; F348-L352 WeakPolarHBondContact O-CB 3.39Å; F348-L352 PolarHBondContact O-N 2.92Å; S349-L352 PolarHBondContact O-N 2.67Å; H350-L352 VanDerWaalsContact C-N 3.27Å; H350-L352 PolarHBondContact O-N 3.42Å; L352-A355 PolarHBondContact O-N 3.02Å; L352-N356 PolarHBondContact O-N 3.09Å
353	V	97.1	Very high	95.4	Very high	9 Å²	9	31.5 Å²	31.5	6%	0.055	15%	0.154	C	C	.	.	H	α-helix	trans	-60.7	-45.1	172.6	168.6	0	0	0	0	110.8	Y317 I320 S349 H350 W351 N356	Y317-V353 HydrophobicContact CD1-CG2 4.22Å; Y317-V353 HydrophobicContact CE1-CG1 3.81Å; Y317-V353 HydrophobicContact CE1-CG2 4.25Å; I320-V353 HydrophobicContact CB-CG2 4.16Å; I320-V353 HydrophobicContact CG2-CG2 3.54Å; S349-V353 WeakPolarHBondContact O-CG2 3.49Å; S349-V353 PolarHBondContact O-N 3.4Å; S349-V353 VanDerWaalsContact O-N 3.12Å; H350-V353 WeakPolarHBondContact O-CB 3.35Å; H350-V353 PolarHBondContact O-N 3.06Å; W351-V353 VanDerWaalsContact C-N 3.33Å; W351-V353 PolarHBondContact O-N 2.9Å; V353-N356 VanDerWaalsContact O-CB 3.28Å; V353-N356 WeakPolarHBondContact O-CB 3.19Å; V353-N356 PolarHBondContact O-N 3.44Å
354	Y	97.5	Very high	95.6	Very high	3 Å²	3	29 Å²	29	1%	0.012	15%	0.145	C	C	.	.	H	α-helix	trans	-72	-32.9	177.2	-64.1	-64.8	0	0	0	112.6	Y61 V64 V103 C107 L108 T111 H350 W351 N356 S357 A358	Y61-Y354 AromaticContact CE1-CD2 3.63Å; Y61-Y354 HydrophobicContact CE1-CD2 3.63Å; Y61-Y354 HydrophobicContact CE1-CE2 4.06Å; V64-Y354 VanDerWaalsContact CG1-C 3.45Å; V64-Y354 VanDerWaalsContact CG1-O 3.31Å; V64-Y354 WeakPolarHBondContact CG1-O 3.27Å; V103-Y354 HydrophobicContact CB-CE1 4.38Å; C107-Y354 HydrophobicContact CB-CE1 4.15Å; C107-Y354 VanDerWaalsContact CB-OH 3.32Å; C107-Y354 WeakPolarHBondContact CB-OH 3.43Å; L108-Y354 HydrophobicContact CB-CD1 3.94Å; L108-Y354 HydrophobicContact CB-CE1 3.91Å; L108-Y354 HydrophobicContact CB-CG 4.28Å; L108-Y354 HydrophobicContact CD1-CD1 4.21Å; L108-Y354 HydrophobicContact CD1-CG 4.07Å; L108-Y354 HydrophobicContact CG-CD1 4.21Å; L108-Y354 HydrophobicContact CG-CD2 4.3Å; L108-Y354 HydrophobicContact CG-CG 4.07Å; T111-Y354 HydrophobicContact CG2-CE2 3.87Å; T111-Y354 PolarHBondContact OG1-OH 3.42Å; H350-Y354 WeakPolarHBondContact O-CD2 3.24Å; H350-Y354 PolarHBondContact O-N 3.39Å; W351-Y354 PolarHBondContact O-N 3.1Å; Y354-N356 PolarHBondContact O-N 3.13Å; Y354-S357 WeakPolarHBondContact O-CB 3.28Å; Y354-S357 PolarHBondContact O-N 3.18Å; Y354-A358 PolarHBondContact O-N 3.15Å
355	A	97.6	Very high	95.8	Very high	17 Å²	17	29.2 Å²	29.2	14%	0.14	14%	0.14	C	C	.	.	H	α-helix	trans	-59.3	-29.3	174.3	0	0	0	0	0	112.1	V64 W351 L352 S357 A358 A359	V64-A355 HydrophobicContact CG2-CB 4.11Å; W351-A355 HydrophobicContact CZ2-CB 4.45Å; W351-A355 PolarHBondContact O-N 2.74Å; L352-A355 PolarHBondContact O-N 3.02Å; A355-S357 VanDerWaalsContact C-N 3.34Å; A355-S357 PolarHBondContact O-N 3.43Å; A355-A358 PolarHBondContact O-N 3.22Å; A355-A359 WeakPolarHBondContact O-CB 3.38Å; A355-A359 PolarHBondContact O-N 3.48Å
356	N	96.6	Very high	95.8	Very high	1 Å²	1	29.1 Å²	29.1	1%	0.005	14%	0.143	C	C	.	.	H	α-helix	trans	-59.2	-42.2	171.6	-179.3	74.1	0	0	0	112.5	F313 C316 Y317 L352 V353 Y354 A358 A359 N360	F313-N356 WeakPolarHBondContact CA-OD1 3.24Å; C316-N356 HydrophobicContact CB-CB 3.73Å; Y317-N356 HydrophobicContact CE2-CB 4.12Å; L352-N356 PolarHBondContact O-N 3.09Å; V353-N356 VanDerWaalsContact O-CB 3.28Å; V353-N356 WeakPolarHBondContact O-CB 3.19Å; V353-N356 PolarHBondContact O-N 3.44Å; Y354-N356 PolarHBondContact O-N 3.13Å; N356-A358 VanDerWaalsContact C-N 3.28Å; N356-A358 PolarHBondContact O-N 3.02Å; N356-A359 WeakPolarHBondContact O-CB 3.47Å; N356-A359 PolarHBondContact O-N 3.46Å; N356-A359 VanDerWaalsContact O-N 3.12Å; N356-N360 PolarHBondContact O-N 2.91Å
357	S	96.8	Very high	95.5	Very high	1 Å²	1	30.4 Å²	30.4	1%	0.007	15%	0.151	C	C	.	.	H	α-helix	trans	-63.3	-35.1	177.5	-59	0	0	0	0	111.8	N72 D100 Y354 A355 P361	N72-S357 PolarHBondContact ND2-O 2.74Å; D100-S357 VanDerWaalsContact CG-OG 3.32Å; D100-S357 WeakPolarHBondContact OD1-CB 3.16Å; D100-S357 PolarHBondContact OD1-OG 3.47Å; Y354-S357 WeakPolarHBondContact O-CB 3.28Å; Y354-S357 PolarHBondContact O-N 3.18Å; A355-S357 VanDerWaalsContact C-N 3.34Å; A355-S357 PolarHBondContact O-N 3.43Å; S357-P361 WeakPolarHBondContact O-CD 3.29Å
358	A	97.6	Very high	95.3	Very high	7 Å²	7	31 Å²	31	6%	0.058	16%	0.155	C	C	.	.	H	α-helix	trans	-72.5	-34.3	172.4	0	0	0	0	0	112.9	V64 V67 A68 Y354 A355 N356 N360 I362	V64-A358 HydrophobicContact CG1-CB 4.24Å; V67-A358 HydrophobicContact CB-CB 4.12Å; V67-A358 HydrophobicContact CG1-CB 3.86Å; A68-A358 HydrophobicContact CB-CB 4.03Å; Y354-A358 PolarHBondContact O-N 3.15Å; A355-A358 PolarHBondContact O-N 3.22Å; N356-A358 VanDerWaalsContact C-N 3.28Å; N356-A358 PolarHBondContact O-N 3.02Å; A358-N360 PolarHBondContact O-N 2.98Å; A358-I362 WeakPolarHBondContact O-CG1 3.2Å
359	A	97.3	Very high	95	Very high	21 Å²	21	27.3 Å²	27.3	17%	0.174	14%	0.144	C	C	.	.	H	α-helix	trans	-67.7	-34.9	-178.3	0	0	0	0	0	112.8	V312 A355 N356 I362 I363	V312-A359 HydrophobicContact CG1-CB 3.87Å; A355-A359 WeakPolarHBondContact O-CB 3.38Å; A355-A359 PolarHBondContact O-N 3.48Å; N356-A359 WeakPolarHBondContact O-CB 3.47Å; N356-A359 PolarHBondContact O-N 3.46Å; N356-A359 VanDerWaalsContact O-N 3.12Å; A359-I362 WeakPolarHBondContact O-CB 3.24Å; A359-I362 PolarHBondContact O-N 3.18Å; A359-I362 VanDerWaalsContact O-N 3.14Å; A359-I363 HydrophobicContact CB-CD1 4.32Å; A359-I363 VanDerWaalsContact O-CG1 3.23Å; A359-I363 WeakPolarHBondContact O-CG1 3.46Å; A359-I363 PolarHBondContact O-N 3.27Å
360	N	93.9	Very high	94.7	Very high	2 Å²	2	32.1 Å²	32.1	1%	0.011	17%	0.165	C	C	.	.	H	α-helix	trans	-52.5	-59.3	-176.7	-80.4	-27.4	0	0	0	113.3	D100 N356 A358 I362 I363 Y364	D100-N360 PolarHBondContact OD2-ND2 3.35Å; N356-N360 PolarHBondContact O-N 2.91Å; A358-N360 PolarHBondContact O-N 2.98Å; N360-I362 VanDerWaalsContact C-N 3.29Å; N360-I362 PolarHBondContact O-N 3.42Å; N360-I363 PolarHBondContact O-N 3.08Å; N360-Y364 HydrophobicContact CB-CE2 4.26Å; N360-Y364 VanDerWaalsContact O-CD1 3.28Å; N360-Y364 WeakPolarHBondContact O-CD1 3.14Å; N360-Y364 WeakPolarHBondContact O-CD2 3.35Å; N360-Y364 PolarHBondContact O-N 3.47Å
361	P	95.6	Very high	94.6	Very high	6 Å²	6	30.3 Å²	30.3	4%	0.039	16%	0.156	C	C	.	.	H	α-helix	trans	-57.4	-37.1	175.6	-26	33.7	0	0	0	114.2	N72 V75 S357 Y364 N365	N72-P361 HydrophobicContact CB-CG 4.44Å; V75-P361 HydrophobicContact CG2-CB 4.25Å; V75-P361 HydrophobicContact CG2-CG 4.28Å; S357-P361 WeakPolarHBondContact O-CD 3.29Å; P361-Y364 PolarHBondContact O-N 3.06Å; P361-N365 WeakPolarHBondContact O-CB 3.39Å; P361-N365 PolarHBondContact O-N 3.27Å
362	I	96.2	Very high	94.4	Very high	79 Å²	79	31.9 Å²	31.9	41%	0.405	16%	0.162	S	C	.	.	H	α-helix	trans	-62.2	-49.2	177.9	-62.4	172.8	0	0	0	109.6	V67 A358 A359 N360 Y364 N365 F366	V67-I362 HydrophobicContact CG1-CD1 4.03Å; V67-I362 HydrophobicContact CG1-CG1 4.38Å; A358-I362 WeakPolarHBondContact O-CG1 3.2Å; A359-I362 WeakPolarHBondContact O-CB 3.24Å; A359-I362 PolarHBondContact O-N 3.18Å; A359-I362 VanDerWaalsContact O-N 3.14Å; N360-I362 VanDerWaalsContact C-N 3.29Å; N360-I362 PolarHBondContact O-N 3.42Å; I362-Y364 PolarHBondContact O-N 3.5Å; I362-N365 WeakPolarHBondContact O-CB 3.47Å; I362-N365 PolarHBondContact O-N 2.96Å; I362-F366 HydrophobicContact CG2-CD2 3.77Å; I362-F366 HydrophobicContact CG2-CE2 3.79Å; I362-F366 VanDerWaalsContact O-CD2 3.28Å; I362-F366 WeakPolarHBondContact O-CD2 3.39Å; I362-F366 PolarHBondContact O-N 3.46Å
363	I	94.4	Very high	94.2	Very high	17 Å²	17	36.3 Å²	36.3	9%	0.087	18%	0.182	C	C	.	.	H	α-helix	trans	-57.6	-42.4	177.4	-64.5	162.7	0	0	0	110.1	V308 V309 V312 A359 N360 F366 L367	V308-I363 HydrophobicContact CG1-CG1 4.49Å; V308-I363 HydrophobicContact CG1-CG2 4.16Å; V309-I363 HydrophobicContact CG2-CB 4.44Å; V309-I363 HydrophobicContact CG2-CD1 4.34Å; V309-I363 HydrophobicContact CG2-CG2 3.66Å; V312-I363 HydrophobicContact CB-CD1 4.06Å; V312-I363 HydrophobicContact CG1-CD1 4.22Å; V312-I363 HydrophobicContact CG2-CD1 3.88Å; A359-I363 HydrophobicContact CB-CD1 4.32Å; A359-I363 VanDerWaalsContact O-CG1 3.23Å; A359-I363 WeakPolarHBondContact O-CG1 3.46Å; A359-I363 PolarHBondContact O-N 3.27Å; N360-I363 PolarHBondContact O-N 3.08Å; I363-F366 PolarHBondContact O-N 3.24Å; I363-L367 HydrophobicContact CG2-CD1 3.65Å; I363-L367 HydrophobicContact CG2-CG 4.28Å; I363-L367 VanDerWaalsContact O-CB 3.3Å; I363-L367 WeakPolarHBondContact O-CB 3.47Å; I363-L367 WeakPolarHBondContact O-CG 3.4Å; I363-L367 PolarHBondContact O-N 3.32Å
364	Y	93.1	Very high	94	Very high	2 Å²	2	37.4 Å²	37.4	1%	0.008	19%	0.187	C	C	.	.	H	α-helix	trans	-65.9	-40.8	179.7	-54.7	-19	0	0	0	112.3	V75 I93 M305 V309 N360 P361 I362 F366 S368	V75-Y364 HydrophobicContact CG1-CD2 4.46Å; V75-Y364 HydrophobicContact CG1-CE2 4.42Å; V75-Y364 HydrophobicContact CG2-CD2 3.72Å; V75-Y364 HydrophobicContact CG2-CE2 4.16Å; I93-Y364 HydrophobicContact CG2-CD2 4.04Å; I93-Y364 HydrophobicContact CG2-CE2 3.42Å; I93-Y364 VanDerWaalsContact CG2-CE2 3.42Å; M305-Y364 HydrophobicContact CE-CD1 3.23Å; M305-Y364 HydrophobicContact CE-CE1 3.86Å; M305-Y364 HydrophobicContact CE-CG 3.92Å; V309-Y364 HydrophobicContact CG2-CD1 4.47Å; V309-Y364 HydrophobicContact CG2-CE1 3.81Å; N360-Y364 HydrophobicContact CB-CE2 4.26Å; N360-Y364 VanDerWaalsContact O-CD1 3.28Å; N360-Y364 WeakPolarHBondContact O-CD1 3.14Å; N360-Y364 WeakPolarHBondContact O-CD2 3.35Å; N360-Y364 PolarHBondContact O-N 3.47Å; P361-Y364 PolarHBondContact O-N 3.06Å; I362-Y364 PolarHBondContact O-N 3.5Å; Y364-F366 PolarHBondContact O-N 2.94Å; Y364-S368 WeakPolarHBondContact O-CA 3.38Å; Y364-S368 VanDerWaalsContact O-CB 3.25Å; Y364-S368 WeakPolarHBondContact O-CB 3.43Å; Y364-S368 PolarHBondContact O-N 3.32Å
365	N	94.3	Very high	93.8	Very high	47 Å²	47	37.8 Å²	37.8	25%	0.251	19%	0.188	S	C	.	.	H	α-helix	trans	-61.6	-42.2	176.2	-175.9	54.3	0	0	0	112.5	P361 I362 R372 F375	P361-N365 WeakPolarHBondContact O-CB 3.39Å; P361-N365 PolarHBondContact O-N 3.27Å; I362-N365 WeakPolarHBondContact O-CB 3.47Å; I362-N365 PolarHBondContact O-N 2.96Å; N365-R372 WeakPolarHBondContact O-CB 3.05Å; N365-R372 WeakPolarHBondContact O-CD 3.46Å; N365-F375 HydrophobicContact CB-CD2 3.86Å; N365-F375 HydrophobicContact CB-CE2 4Å
366	F	93.1	Very high	93.5	Very high	141 Å²	141	43.4 Å²	43.4	62%	0.618	21%	0.209	S	C	*	.	H	α-helix	trans	-78.6	-39	-179.2	-79	-76.7	0	0	0	113.1	I362 I363 Y364	I362-F366 HydrophobicContact CG2-CD2 3.77Å; I362-F366 HydrophobicContact CG2-CE2 3.79Å; I362-F366 VanDerWaalsContact O-CD2 3.28Å; I362-F366 WeakPolarHBondContact O-CD2 3.39Å; I362-F366 PolarHBondContact O-N 3.46Å; I363-F366 PolarHBondContact O-N 3.24Å; Y364-F366 PolarHBondContact O-N 2.94Å
367	L	88.4	Confident	93.2	Very high	49 Å²	49	45.8 Å²	45.8	26%	0.257	23%	0.23	S	C	.	.	H	α-helix	trans	-99.9	-18.5	-169.1	-57.2	-176	0	0	0	114.1	K301 M305 V308 I363	K301-L367 WeakPolarHBondContact CE-O 3.34Å; M305-L367 HydrophobicContact CB-CB 3.83Å; M305-L367 HydrophobicContact CB-CD1 4.24Å; M305-L367 HydrophobicContact CG-CB 3.77Å; M305-L367 HydrophobicContact CG-CD1 4.36Å; V308-L367 HydrophobicContact CB-CD1 3.8Å; V308-L367 HydrophobicContact CG1-CD1 3.97Å; V308-L367 HydrophobicContact CG2-CD1 3.91Å; I363-L367 HydrophobicContact CG2-CD1 3.65Å; I363-L367 HydrophobicContact CG2-CG 4.28Å; I363-L367 VanDerWaalsContact O-CB 3.3Å; I363-L367 WeakPolarHBondContact O-CB 3.47Å; I363-L367 WeakPolarHBondContact O-CG 3.4Å; I363-L367 PolarHBondContact O-N 3.32Å
368	S	89.4	Confident	92.7	Very high	20 Å²	20	47 Å²	47	14%	0.14	24%	0.24	C	C	.	.			trans	-111.6	115.8	175.7	-177.5	0	0	0	0	112.1	Y364 K370 F371 R372	Y364-S368 WeakPolarHBondContact O-CA 3.38Å; Y364-S368 VanDerWaalsContact O-CB 3.25Å; Y364-S368 WeakPolarHBondContact O-CB 3.43Å; Y364-S368 PolarHBondContact O-N 3.32Å; S368-K370 VanDerWaalsContact C-N 3.28Å; S368-K370 PolarHBondContact O-N 3.46Å; S368-F371 PolarHBondContact O-N 3.22Å; S368-F371 WeakPolarHBondContact OG-CD2 3.35Å; S368-R372 WeakPolarHBondContact O-CB 3.33Å; S368-R372 PolarHBondContact O-N 3.03Å; S368-R372 VanDerWaalsContact O-N 3.09Å
369	G	88.8	Confident	92.2	Very high	16 Å²	16	52 Å²	52	17%	0.165	26%	0.261	C	S	.	.	H	α-helix	trans	-61.2	-37.4	177.9	0	0	0	0	0	112.7	R372 E373	G369-R372 PolarHBondContact O-N 3.2Å; G369-E373 WeakPolarHBondContact O-CG 3.36Å; G369-E373 PolarHBondContact O-N 2.8Å; G369-E373 VanDerWaalsContact O-N 3.09Å
370	K	90.4	Very high	91.5	Very high	101 Å²	101	53.9 Å²	53.9	44%	0.439	27%	0.272	S	S	.	.	H	α-helix	trans	-68.3	-46.2	-179.8	-58.3	-174.5	175.4	-173.8	0	112.1	M85 S368 R372 E373 E374	M85-K370 HydrophobicContact CE-CB 3.94Å; M85-K370 HydrophobicContact SD-CB 3.46Å; M85-K370 WeakPolarHBondContact SD-CB 3.23Å; M85-K370 HydrophobicContact SD-CD 3.71Å; M85-K370 HydrophobicContact SD-CG 4.23Å; S368-K370 VanDerWaalsContact C-N 3.28Å; S368-K370 PolarHBondContact O-N 3.46Å; K370-R372 VanDerWaalsContact C-N 3.29Å; K370-R372 PolarHBondContact O-N 3.34Å; K370-E373 PolarHBondContact O-N 3.07Å; K370-E374 WeakPolarHBondContact O-CG 3.4Å; K370-E374 PolarHBondContact O-N 3.42Å; K370-E374 VanDerWaalsContact O-N 3.14Å
371	F	93	Very high	90.6	Very high	1 Å²	1	57.8 Å²	57.8	0%	0.004	30%	0.299	C	S	.	.	H	α-helix	trans	-62.3	-40.1	176.5	-82	-68.9	0	0	0	111.4	V75 A78 V79 M85 I93 S368 E373 E374 F375	V75-F371 HydrophobicContact CG1-CE1 4.1Å; V75-F371 HydrophobicContact CG1-CZ 4.46Å; A78-F371 HydrophobicContact CB-CD1 4.34Å; A78-F371 HydrophobicContact CB-CE1 4.44Å; V79-F371 HydrophobicContact CG2-CE1 3.78Å; V79-F371 HydrophobicContact CG2-CZ 3.87Å; M85-F371 HydrophobicContact CE-CD1 3.61Å; M85-F371 HydrophobicContact CE-CD2 4Å; M85-F371 HydrophobicContact CE-CE1 3.63Å; M85-F371 HydrophobicContact CE-CE2 4Å; M85-F371 HydrophobicContact CE-CG 3.79Å; M85-F371 HydrophobicContact CE-CZ 3.82Å; I93-F371 HydrophobicContact CD1-CE2 4.12Å; I93-F371 HydrophobicContact CD1-CZ 4.46Å; I93-F371 HydrophobicContact CG2-CZ 4.07Å; S368-F371 PolarHBondContact O-N 3.22Å; S368-F371 WeakPolarHBondContact OG-CD2 3.35Å; F371-E373 VanDerWaalsContact C-N 3.34Å; F371-E373 PolarHBondContact O-N 2.97Å; F371-E374 PolarHBondContact O-N 3.06Å; F371-F375 HydrophobicContact CD1-CE1 4.17Å; F371-F375 HydrophobicContact CD1-CZ 4.33Å; F371-F375 WeakPolarHBondContact O-CB 3.29Å; F371-F375 WeakPolarHBondContact O-CD1 3.43Å; F371-F375 VanDerWaalsContact O-CG 3.26Å; F371-F375 WeakPolarHBondContact O-CG 3.32Å; F371-F375 PolarHBondContact O-N 3.32Å
372	R	93.9	Very high	89.4	Confident	103 Å²	103	62.3 Å²	62.3	39%	0.389	33%	0.329	S	S	.	.	H	α-helix	trans	-60.1	-40.5	176.1	-171.4	171.5	62.4	-167.4	4.8	113.4	N365 S368 G369 K370 K376	N365-R372 WeakPolarHBondContact O-CB 3.05Å; N365-R372 WeakPolarHBondContact O-CD 3.46Å; S368-R372 WeakPolarHBondContact O-CB 3.33Å; S368-R372 PolarHBondContact O-N 3.03Å; S368-R372 VanDerWaalsContact O-N 3.09Å; G369-R372 PolarHBondContact O-N 3.2Å; K370-R372 VanDerWaalsContact C-N 3.29Å; K370-R372 PolarHBondContact O-N 3.34Å; R372-K376 WeakPolarHBondContact O-CB 3.11Å; R372-K376 VanDerWaalsContact O-CG 3.31Å; R372-K376 WeakPolarHBondContact O-CG 3.4Å; R372-K376 PolarHBondContact O-N 2.85Å; R372-K376 VanDerWaalsContact O-N 3.08Å
373	E	93	Very high	87.9	Confident	120 Å²	120	63.3 Å²	63.3	56%	0.561	34%	0.342	S	S	*	.	H	α-helix	trans	-64.5	-45.5	176.3	-75.8	165.4	-166.4	0	0	111.2	G369 K370 F371 K376 A377	G369-E373 WeakPolarHBondContact O-CG 3.36Å; G369-E373 PolarHBondContact O-N 2.8Å; G369-E373 VanDerWaalsContact O-N 3.09Å; K370-E373 PolarHBondContact O-N 3.07Å; F371-E373 VanDerWaalsContact C-N 3.34Å; F371-E373 PolarHBondContact O-N 2.97Å; E373-K376 PolarHBondContact O-N 3.34Å; E373-A377 WeakPolarHBondContact O-CB 3.12Å; E373-A377 PolarHBondContact O-N 3.44Å
374	E	93.5	Very high	85.8	Confident	32 Å²	32	68.1 Å²	68.1	15%	0.15	37%	0.368	C	S	.	.	H	α-helix	trans	-66.4	-38.7	178.2	-65	-54.4	150.8	0	0	113.2	A78 N82 H84 K370 F371 A377 A378	A78-E374 HydrophobicContact CB-CB 3.73Å; A78-E374 HydrophobicContact CB-CG 4.23Å; N82-E374 VanDerWaalsContact CG-CD 3.49Å; N82-E374 VanDerWaalsContact CG-OE2 3.3Å; N82-E374 PolarHBondContact ND2-OE2 2.98Å; H84-E374 IonicContact CE1-OE1 3.24Å; H84-E374 PolarHBondContact CE1-OE1 2.88Å; H84-E374 IonicContact NE2-OE1 3.74Å; K370-E374 WeakPolarHBondContact O-CG 3.4Å; K370-E374 PolarHBondContact O-N 3.42Å; K370-E374 VanDerWaalsContact O-N 3.14Å; F371-E374 PolarHBondContact O-N 3.06Å; E374-A377 PolarHBondContact O-N 3.43Å; E374-A378 WeakPolarHBondContact O-CB 3.5Å; E374-A378 PolarHBondContact O-N 2.99Å
375	F	92.9	Very high	83.6	Confident	11 Å²	11	69.9 Å²	69.9	5%	0.048	39%	0.386	C	S	.	.	H	α-helix	trans	-64.9	-44.6	175.9	-70.5	0.7	0	0	0	110.8	L74 V75 A78 N365 F371 A377 A378 F379	L74-F375 HydrophobicContact CB-CD1 4.11Å; L74-F375 HydrophobicContact CB-CE1 3.82Å; L74-F375 HydrophobicContact CB-CZ 4.37Å; V75-F375 HydrophobicContact CG2-CE1 4.33Å; V75-F375 HydrophobicContact CG2-CZ 3.73Å; A78-F375 HydrophobicContact CB-CE1 4.36Å; N365-F375 HydrophobicContact CB-CD2 3.86Å; N365-F375 HydrophobicContact CB-CE2 4Å; F371-F375 HydrophobicContact CD1-CE1 4.17Å; F371-F375 HydrophobicContact CD1-CZ 4.33Å; F371-F375 WeakPolarHBondContact O-CB 3.29Å; F371-F375 WeakPolarHBondContact O-CD1 3.43Å; F371-F375 VanDerWaalsContact O-CG 3.26Å; F371-F375 WeakPolarHBondContact O-CG 3.32Å; F371-F375 PolarHBondContact O-N 3.32Å; F375-A377 VanDerWaalsContact C-N 3.33Å; F375-A377 PolarHBondContact O-N 2.99Å; F375-A378 PolarHBondContact O-N 3.37Å; F375-F379 HydrophobicContact CB-CE2 4.43Å; F375-F379 WeakPolarHBondContact O-CD2 3.45Å; F375-F379 PolarHBondContact O-N 3.37Å
376	K	91.7	Very high	81.4	Confident	134 Å²	134	73.2 Å²	73.2	58%	0.583	41%	0.408	S	S	*	.	H	α-helix	trans	-58.7	-44.8	173.4	-75.4	179.9	178.5	-166.4	0	111.7	R372 E373 A378 F379 S380	R372-K376 WeakPolarHBondContact O-CB 3.11Å; R372-K376 VanDerWaalsContact O-CG 3.31Å; R372-K376 WeakPolarHBondContact O-CG 3.4Å; R372-K376 PolarHBondContact O-N 2.85Å; R372-K376 VanDerWaalsContact O-N 3.08Å; E373-K376 PolarHBondContact O-N 3.34Å; K376-A378 VanDerWaalsContact C-N 3.32Å; K376-A378 PolarHBondContact O-N 2.91Å; K376-F379 PolarHBondContact O-N 2.96Å; K376-S380 WeakPolarHBondContact O-CB 3.4Å; K376-S380 PolarHBondContact O-N 3.26Å; K376-S380 PolarHBondContact O-OG 3.42Å; K376-S380 VanDerWaalsContact O-OG 3.09Å
377	A	89.7	Confident	79	Confident	52 Å²	52	74.1 Å²	74.1	43%	0.43	41%	0.414	S	S	.	.	H	α-helix	trans	-62	-39.8	178	0	0	0	0	0	112.2	E373 E374 F375 C381	E373-A377 WeakPolarHBondContact O-CB 3.12Å; E373-A377 PolarHBondContact O-N 3.44Å; E374-A377 PolarHBondContact O-N 3.43Å; F375-A377 VanDerWaalsContact C-N 3.33Å; F375-A377 PolarHBondContact O-N 2.99Å; A377-C381 VanDerWaalsContact O-CB 3.23Å; A377-C381 WeakPolarHBondContact O-CB 3.2Å; A377-C381 PolarHBondContact O-N 2.88Å
378	A	87	Confident	76.9	Confident	27 Å²	27	77.7 Å²	77.7	22%	0.223	43%	0.429	C	S	.	.	H	α-helix	trans	-63.8	-49.2	175.9	0	0	0	0	0	111.8	L74 E374 F375 K376 C381 C382	L74-A378 HydrophobicContact CD2-CB 3.78Å; E374-A378 WeakPolarHBondContact O-CB 3.5Å; E374-A378 PolarHBondContact O-N 2.99Å; F375-A378 PolarHBondContact O-N 3.37Å; K376-A378 VanDerWaalsContact C-N 3.32Å; K376-A378 PolarHBondContact O-N 2.91Å; A378-C381 PolarHBondContact O-N 3.2Å; A378-C382 PolarHBondContact O-N 3.37Å; A378-C382 PolarHBondContact O-SG 3.21Å
379	F	86.4	Confident	74.6	Confident	112 Å²	112	86.2 Å²	86.2	49%	0.491	46%	0.458	S	S	.	.	H	α-helix	trans	-65.3	-40.8	177.9	-70.6	-63.6	0	0	0	112.4	L74 F375 K376 C381 C382 C383	L74-F379 HydrophobicContact CD1-CE1 4.28Å; L74-F379 HydrophobicContact CD1-CE2 3.85Å; L74-F379 HydrophobicContact CD1-CZ 3.5Å; F375-F379 HydrophobicContact CB-CE2 4.43Å; F375-F379 WeakPolarHBondContact O-CD2 3.45Å; F375-F379 PolarHBondContact O-N 3.37Å; K376-F379 PolarHBondContact O-N 2.96Å; F379-C381 PolarHBondContact O-N 3.4Å; F379-C382 PolarHBondContact O-N 3.48Å; F379-C383 WeakPolarHBondContact O-CB 3.48Å; F379-C383 PolarHBondContact O-N 2.81Å; F379-C383 PolarHBondContact O-SG 3.48Å
380	S	82.9	Confident	72.5	Confident	60 Å²	60	92.3 Å²	92.3	42%	0.42	48%	0.482	S	S	.	.	H	α-helix	trans	-63.7	-40.3	174.8	-66.6	0	0	0	0	112.1	K376 C382 L384	K376-S380 WeakPolarHBondContact O-CB 3.4Å; K376-S380 PolarHBondContact O-N 3.26Å; K376-S380 PolarHBondContact O-OG 3.42Å; K376-S380 VanDerWaalsContact O-OG 3.09Å; S380-C382 PolarHBondContact O-N 3.5Å; S380-L384 WeakPolarHBondContact O-CB 3.37Å; S380-L384 PolarHBondContact O-N 3.26Å
381	C	74.1	Confident	70.3	Confident	84 Å²	84	93.7 Å²	93.7	57%	0.568	49%	0.49	S	S	*	.	H	α-helix	trans	-65.2	-38.5	176.8	-172.7	0	0	0	0	112.4	A377 A378 F379 G385	A377-C381 VanDerWaalsContact O-CB 3.23Å; A377-C381 WeakPolarHBondContact O-CB 3.2Å; A377-C381 PolarHBondContact O-N 2.88Å; A378-C381 PolarHBondContact O-N 3.2Å; F379-C381 PolarHBondContact O-N 3.4Å; C381-G385 WeakPolarHBondContact O-CA 3.12Å; C381-G385 PolarHBondContact O-N 3.48Å; C381-G385 VanDerWaalsContact O-N 3.11Å
382	C	71.7	Confident	68	Low	101 Å²	101	98.6 Å²	98.6	68%	0.682	52%	0.517	S	S	*	.	H	α-helix	trans	-75.1	-35	179	-64.8	0	0	0	0	112.7	A378 F379 S380	A378-C382 PolarHBondContact O-N 3.37Å; A378-C382 PolarHBondContact O-SG 3.21Å; F379-C382 PolarHBondContact O-N 3.48Å; S380-C382 PolarHBondContact O-N 3.5Å
383	C	63.8	Low	65.5	Low	100 Å²	100	103.5 Å²	103.5	68%	0.676	54%	0.535	S	S	*	.	H	α-helix	trans	-88.9	-31.2	-178.2	-60.1	0	0	0	0	113.9	F379	F379-C383 WeakPolarHBondContact O-CB 3.48Å; F379-C383 PolarHBondContact O-N 2.81Å; F379-C383 PolarHBondContact O-SG 3.48Å
384	L	50.7	Low	63.2	Low	118 Å²	118	104.1 Å²	104.1	62%	0.618	54%	0.542	S	S	*	.	H	α-helix	trans	-98.9	-12.7	179.4	-69	142.8	0	0	0	113.5	S380 V386 H387	S380-L384 WeakPolarHBondContact O-CB 3.37Å; S380-L384 PolarHBondContact O-N 3.26Å; L384-V386 PolarHBondContact O-N 3.4Å; L384-V386 VanDerWaalsContact O-N 3.15Å; L384-H387 PolarHBondContact O-N 2.77Å; L384-H387 VanDerWaalsContact O-N 3.15Å
385	G	47.3	Very low	60.9	Low	39 Å²	39	106.8 Å²	106.8	40%	0.402	56%	0.56	S	S	.	*	T	Hydrogen-bonded Turn	trans	-66.9	-9.9	179.2	0	0	0	0	0	115.2	C381	C381-G385 WeakPolarHBondContact O-CA 3.12Å; C381-G385 PolarHBondContact O-N 3.48Å; C381-G385 VanDerWaalsContact O-N 3.11Å
386	V	48.3	Very low	58.4	Low	117 Å²	117	116.8 Å²	116.8	71%	0.709	60%	0.598	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80	-30.1	173.3	-178.9	0	0	0	0	111.5	L384	L384-V386 PolarHBondContact O-N 3.4Å; L384-V386 VanDerWaalsContact O-N 3.15Å
387	H	42.6	Very low	55.7	Low	160 Å²	160	113.8 Å²	113.8	74%	0.741	61%	0.605	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88	-30.6	-175.6	-121	-74.3	0	0	0	113.8	L384 R389	L384-H387 PolarHBondContact O-N 2.77Å; L384-H387 VanDerWaalsContact O-N 3.15Å; H387-R389 PolarHBondContact O-N 3.25Å
388	H	44.2	Very low	53.3	Low	123 Å²	123	122.1 Å²	122.1	57%	0.569	63%	0.625	S	S	*	*	H	α-helix	trans	-79.7	-19.2	-173.3	-141.4	-27	0	0	0	114.1	Q390	H388-Q390 VanDerWaalsContact C-N 3.31Å; H388-Q390 PolarHBondContact O-N 3.45Å
389	R	40.4	Very low	50.9	Low	199 Å²	199	126.9 Å²	126.9	75%	0.751	65%	0.652	S	S	*	*	H	α-helix	trans	-79.2	-11.5	-176.3	-145.1	177.6	-171.2	-164.5	2.6	114	H387	H387-R389 PolarHBondContact O-N 3.25Å
390	Q	44.4	Very low	48.6	Very low	145 Å²	145	126.5 Å²	126.5	68%	0.678	66%	0.662	S	S	*	*	H	α-helix	trans	-95	-31.9	179.4	-163.2	154.2	-10.8	0	0	112.4	H388 R393	H388-Q390 VanDerWaalsContact C-N 3.31Å; H388-Q390 PolarHBondContact O-N 3.45Å; Q390-R393 PolarHBondContact O-N 2.86Å
391	E	43.7	Very low	46.5	Very low	130 Å²	130	129.9 Å²	129.9	61%	0.607	68%	0.681	S	S	*	*	H	α-helix	trans	-71	-37.6	177.5	-117	172.8	168.2	0	0	112.8	R393 L394 T395	E391-R393 PolarHBondContact O-N 2.98Å; E391-L394 PolarHBondContact O-N 3.17Å; E391-T395 PolarHBondContact O-N 3.4Å; E391-T395 PolarHBondContact O-OG1 3.35Å
392	D	45.5	Very low	44.5	Very low	104 Å²	104	135.5 Å²	135.5	56%	0.556	70%	0.699	S	S	*	*	H	α-helix	trans	-69.2	-17.5	177.2	-81.2	-14.6	0	0	0	113.9	R396	D392-R396 WeakPolarHBondContact O-CB 3.5Å
393	R	41.8	Very low	42.6	Very low	205 Å²	205	135.9 Å²	135.9	77%	0.774	70%	0.703	S	S	*	*	H	α-helix	trans	-84.9	-25.2	174.5	-77.8	-172.4	175.1	-162.9	-1.1	112.9	Q390 E391	Q390-R393 PolarHBondContact O-N 2.86Å; E391-R393 PolarHBondContact O-N 2.98Å
394	L	45	Very low	41.2	Very low	134 Å²	134	141.2 Å²	141.2	70%	0.702	71%	0.709	S	S	*	*	H	α-helix	trans	-84.8	-31.9	178.6	-84.4	149.8	0	0	0	112.5	E391	E391-L394 PolarHBondContact O-N 3.17Å
395	T	43.8	Very low	40.2	Very low	87 Å²	87	144.6 Å²	144.6	53%	0.534	72%	0.718	S	S	.	*	H	α-helix	trans	-78	-25	177	38.6	0	0	0	0	113.7	E391 G397	E391-T395 PolarHBondContact O-N 3.4Å; E391-T395 PolarHBondContact O-OG1 3.35Å; T395-G397 VanDerWaalsContact C-N 3.3Å; T395-G397 PolarHBondContact O-N 3.3Å
396	R	40.5	Very low	39.4	Very low	222 Å²	222	147.6 Å²	147.6	84%	0.838	73%	0.733	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.1	-10.5	179	-168.3	168.5	165.6	168.1	-3.6	114.4	D392	D392-R396 WeakPolarHBondContact O-CB 3.5Å
397	G	35.7	Very low	38.7	Very low	71 Å²	71	149.7 Å²	149.7	73%	0.732	74%	0.74	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.4	-4.1	177.6	0	0	0	0	0	115.3	T395	T395-G397 VanDerWaalsContact C-N 3.3Å; T395-G397 PolarHBondContact O-N 3.3Å
398	R	38.8	Very low	38.2	Very low	227 Å²	227	148.9 Å²	148.9	86%	0.857	75%	0.746	S	S	*	*	S	Bend	trans	-127	9.4	-165.5	-143.9	169.2	164	154.2	-4	115.4
399	T	36.8	Very low	37.6	Very low	127 Å²	127	149 Å²	149	78%	0.779	76%	0.755	S	S	*	*			trans	-123.4	55.8	179.4	48	0	0	0	0	111.5
400	S	37.9	Very low	37.3	Very low	103 Å²	103	148.1 Å²	148.1	72%	0.72	76%	0.76	S	S	*	*	S	Bend	trans	-123	136.2	149.7	-174.2	0	0	0	0	106.1
401	T	40.3	Very low	36.8	Very low	132 Å²	132	149.4 Å²	149.4	81%	0.81	77%	0.77	S	S	*	*	S	Bend	trans	72.6	81.7	-171	73.9	0	0	0	0	115.9
402	E	31.5	Very low	36.4	Very low	201 Å²	201	148 Å²	148	94%	0.939	77%	0.774	S	S	*	*				-170.4	132.8	109.7	-105.2	-174.8	162.7	0	0	112.2
403	S	31.2	Very low	35.8	Very low	109 Å²	109	149.5 Å²	149.5	76%	0.762	78%	0.782	S	S	*	*			trans	-105.8	120.5	178.6	177.6	0	0	0	0	108.1
404	R	33.8	Very low	35.5	Very low	213 Å²	213	149 Å²	149	80%	0.804	79%	0.786	S	S	*	*			trans	152.5	134	135.3	-91.7	176.4	-178.9	177.2	2.5	114.3
405	K	31.7	Very low	35.2	Very low	188 Å²	188	148.7 Å²	148.7	82%	0.817	79%	0.785	S	S	*	*			trans	73.6	110.8	143.4	-68.1	175.4	179.1	-173	0	119.5
406	S	29.6	Very low	34.8	Very low	103 Å²	103	150 Å²	150	72%	0.72	79%	0.788	S	S	*	*				161.8	102.5	119.1	-169.3	0	0	0	0	107.9
407	L	32.7	Very low	34.7	Very low	161 Å²	161	146.2 Å²	146.2	84%	0.843	78%	0.784	S	S	*	*				50.7	73.5	90.4	-152.5	83.7	0	0	0	114.7
408	T	32.2	Very low	34.8	Very low	142 Å²	142	146.5 Å²	146.5	87%	0.871	78%	0.775	S	S	*	*			trans	-152.5	73.4	150.2	-4.3	0	0	0	0	110.1
409	T	33.2	Very low	34.7	Very low	125 Å²	125	143.1 Å²	143.1	77%	0.767	77%	0.766	S	S	*	*			trans	-78.8	133	155.9	-41.5	0	0	0	0	107
410	Q	33.4	Very low	34.6	Very low	181 Å²	181	143.3 Å²	143.3	85%	0.846	76%	0.762	S	S	*	*			trans	138.7	93.6	156.4	-68.8	-110.1	-0.7	0	0	108.7
411	I	34.8	Very low	34.6	Very low	172 Å²	172	142.2 Å²	142.2	88%	0.882	75%	0.754	S	S	*	*	S	Bend	trans	154.3	83.1	153	-72.7	148.9	0	0	0	106
412	S	33.5	Very low	34.5	Very low	100 Å²	100	143.8 Å²	143.8	70%	0.699	75%	0.752	S	S	*	*	S	Bend	trans	-177.9	-8.1	160.7	53.7	0	0	0	0	113.8	F414	S412-F414 VanDerWaalsContact C-N 3.28Å; S412-F414 PolarHBondContact O-N 2.84Å
413	N	33.8	Very low	34.7	Very low	136 Å²	136	142 Å²	142	73%	0.727	74%	0.744	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.9	10.2	-179.5	-85.7	-8	0	0	0	115.9
414	F	35.4	Very low	34.8	Very low	195 Å²	195	141.9 Å²	141.9	86%	0.855	74%	0.738	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88	-12.1	-178.5	-134.1	-92.2	0	0	0	114.9	S412	S412-F414 VanDerWaalsContact C-N 3.28Å; S412-F414 PolarHBondContact O-N 2.84Å
415	D	37.9	Very low	35	Very low	127 Å²	127	137.4 Å²	137.4	68%	0.679	73%	0.734	S	S	*	*	S	Bend	trans	-94.8	-13.7	-174.7	-78.8	-26.3	0	0	0	115.1	S418	D415-S418 PolarHBondContact O-OG 2.91Å
416	N	36.2	Very low	35.1	Very low	114 Å²	114	136.1 Å²	136.1	61%	0.61	74%	0.735	S	S	*	*	T	Hydrogen-bonded Turn	trans	-85.4	-11.9	-175.8	-81.7	-24.4	0	0	0	115
417	I	38.8	Very low	35.4	Very low	144 Å²	144	137.5 Å²	137.5	74%	0.738	74%	0.739	S	S	*	*	T	Hydrogen-bonded Turn	trans	-82.6	-15.9	179.3	-64.1	176.8	0	0	0	112.1
418	S	36.5	Very low	35.5	Very low	77 Å²	77	134.4 Å²	134.4	54%	0.538	73%	0.732	S	S	.	*	S	Bend	trans	-79.6	-20.4	-179.8	68.7	0	0	0	0	114.8	D415 S421	D415-S418 PolarHBondContact O-OG 2.91Å; S418-S421 PolarHBondContact O-OG 3.18Å
419	K	37.9	Very low	35.7	Very low	155 Å²	155	135.8 Å²	135.8	67%	0.674	73%	0.732	S	S	*	*	S	Bend	trans	-93.8	-17.9	-174.8	-76.1	-178.5	179.5	170	0	114.6
420	L	35.1	Very low	35.7	Very low	132 Å²	132	135 Å²	135	69%	0.691	73%	0.732	S	S	*	*	S	Bend	trans	-81.7	-19.2	178	-108.7	86.9	0	0	0	113.6	E422	L420-E422 VanDerWaalsContact C-N 3.33Å; L420-E422 PolarHBondContact O-N 3.32Å
421	S	37.4	Very low	35.6	Very low	79 Å²	79	133.2 Å²	133.2	55%	0.552	73%	0.733	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.4	-16.2	-179.7	57.5	0	0	0	0	114.3	S418	S418-S421 PolarHBondContact O-OG 3.18Å
422	E	38.6	Very low	35.5	Very low	165 Å²	165	133.3 Å²	133.3	77%	0.771	74%	0.735	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.4	-16.2	179.2	-77.6	-170.9	150.8	0	0	113.6	L420	L420-E422 VanDerWaalsContact C-N 3.33Å; L420-E422 PolarHBondContact O-N 3.32Å
423	Q	35.4	Very low	35.6	Very low	165 Å²	165	134.3 Å²	134.3	77%	0.771	74%	0.739	S	S	*	*	S	Bend	trans	-95.1	-14.4	-173.9	-113.9	168.1	-13.9	0	0	115
424	V	33.9	Very low	35.5	Very low	105 Å²	105	133 Å²	133	64%	0.636	75%	0.747	S	S	*	*	S	Bend	trans	-94.5	-14.5	-174.1	-179.5	0	0	0	0	113.5	L426	V424-L426 VanDerWaalsContact C-N 3.33Å; V424-L426 PolarHBondContact O-N 2.9Å
425	V	36.2	Very low	35.3	Very low	120 Å²	120	127.9 Å²	127.9	73%	0.727	74%	0.74	S	S	*	*	T	Hydrogen-bonded Turn	trans	-82.2	-4.7	-171.5	-177.7	0	0	0	0	113.9
426	L	35.4	Very low	35	Very low	161 Å²	161	130 Å²	130	84%	0.843	75%	0.752	S	S	*	*	T	Hydrogen-bonded Turn	trans	-101.9	9.2	-171.2	-111.7	147.2	0	0	0	116.2	V424	V424-L426 VanDerWaalsContact C-N 3.33Å; V424-L426 PolarHBondContact O-N 2.9Å
427	T	35.8	Very low	34.7	Very low	131 Å²	131	128.5 Å²	128.5	80%	0.804	76%	0.763	S	S	*	*	S	Bend	trans	-123.1	5.4	-174.5	18.6	0	0	0	0	117
428	S	34.7	Very low	34.5	Very low	97 Å²	97	127 Å²	127	68%	0.678	77%	0.773	S	S	*	*			trans	-141.4	63	-175.8	64.1	0	0	0	0	114.4
429	I	34.8	Very low	34.2	Very low	170 Å²	170	126.8 Å²	126.8	87%	0.872	78%	0.782	S	S	*	*			trans	-141.9	82	157.5	-51.9	179.2	0	0	0	109.3
430	S	34.8	Very low	34.6	Very low	110 Å²	110	125.6 Å²	125.6	77%	0.769	79%	0.79	S	S	*	*			trans	-157.6	80.5	156.1	61.7	0	0	0	0	110.6
431	T	31.1	Very low	34.5	Very low	143 Å²	143	127 Å²	127	88%	0.877	80%	0.798	S	S	*	*			trans	-167.3	109.2	151.7	37.9	0	0	0	0	108.6
432	L	33.2	Very low	34.3	Very low	174 Å²	174	130.9 Å²	130.9	91%	0.911	81%	0.807	S	S	*	*	P	Polyproline II helix	trans	-74.5	143.7	164.5	-89.7	127.7	0	0	0	109.7
433	P	35.5	Very low	34	Very low	121 Å²	121	129 Å²	129	79%	0.786	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-94.5	131.4	156.9	25.6	-11.9	0	0	0	110.5
434	A	31.3	Very low	34	Very low	108 Å²	108	136.4 Å²	136.4	89%	0.893	82%	0.823	S	S	*	*	P	Polyproline II helix	trans	-85.7	136.8	166.8	0	0	0	0	0	109.6
435	A	31.8	Very low	34.1	Very low	88 Å²	88	138 Å²	138	73%	0.727	83%	0.833	S	S	*	*			trans	-138.4	115.9	168.7	0	0	0	0	0	109.9
436	N	31.8	Very low	33.9	Very low	171 Å²	171	138.9 Å²	138.9	91%	0.914	84%	0.838	S	S	*	*				154.2	131.7	124.7	-82.8	-9.4	0	0	0	112.3
437	G	29.8	Very low	33.9	Very low	83 Å²	83	137.7 Å²	137.7	86%	0.856	84%	0.838	S	S	*	*			trans	167.4	92.4	167	0	0	0	0	0	111.7
438	A	34.1	Very low	33.8	Very low	113 Å²	113	138.1 Å²	138.1	93%	0.934	84%	0.84	S	S	*	*			trans	-73.3	151.3	-179.8	0	0	0	0	0	113.5
439	G	30.3	Very low	33.7	Very low	72 Å²	72	140.6 Å²	140.6	74%	0.742	85%	0.85	S	S	*	*			trans	177.1	121.2	162.2	0	0	0	0	0	111.1
440	P	46.4	Very low	33.6	Very low	129 Å²	129	138.7 Å²	138.7	84%	0.838	85%	0.849	S	S	*	*			trans	-98.6	132.2	176.8	34.2	-25.6	0	0	0	111
441	L	32.3	Very low	33.5	Very low	162 Å²	162	140.7 Å²	140.7	85%	0.848	85%	0.854	S	S	*	*			trans	-146	100.7	164.2	-97.9	159.2	0	0	0	109.9
442	Q	33.4	Very low	33.7	Very low	160 Å²	160	140.5 Å²	140.5	75%	0.748	85%	0.853	S	S	*	*			trans	14.4	122.5	132.9	-89.9	172	-29.4	0	0	118.6
443	N	31.9	Very low	33.8	Very low	127 Å²	127	137.8 Å²	137.8	68%	0.679	85%	0.848	S	S	*	*				153.4	140.8	99.4	-91.4	-17.9	0	0	0	113.2
444	W	36.6	Very low	33.6	Very low	319 Å²	319	139.3 Å²	139.3	100%	1.208	85%	0.853	S	S	*	*			trans	79.4	0	170.4	-59.3	99	0	0	0	118.4

Retrieved 444 of 444 residues in 1110.7 ms (Link to these results)

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