A0A2K5MPM1_CERAT Loading...

phosphopyruvate hydratase

AlphaFold DB , UniProt , Accession A0A2K5MPM1, Species CERAT (Cercocebus atys, Sooty mangabey), Gene ENO1, Length 434 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M78.8Confident95.7Very high52 Ų5248.5 Ų48.526%0.25624%0.235SC..  0145.30-179.4178.1-6800112.1S27 K28 N83 V84 E125M1-S27 WeakPolarHBondContact CE-OG 3.37Å; M1-S27 PolarHBondContact SD-OG 3.25Å; M1-K28 HydrophobicContact CE-CD 4.41Å; M1-K28 HydrophobicContact CE-CG 4Å; M1-K28 HydrophobicContact SD-CG 3.88Å; M1-N83 PolarHBondContact N-ND2 3.44Å; M1-N83 PolarHBondContact N-OD1 3.43Å; M1-N83 WeakPolarHBondContact O-CA 3.4Å; M1-N83 PolarHBondContact O-OD1 3.47Å; M1-V84 PolarHBondContact O-N 3.03Å; M1-V84 VanDerWaalsContact O-N 3.09Å; M1-E125 WeakPolarHBondContact CA-OE1 3.33Å; M1-E125 HydrophobicContact CB-CG 4.31Å; M1-E125 WeakPolarHBondContact CB-OE1 3.4Å; M1-E125 VanDerWaalsContact CB-OE2 3.26Å; M1-E125 WeakPolarHBondContact CB-OE2 3.35Å; M1-E125 VanDerWaalsContact CE-OE2 3.28Å; M1-E125 WeakPolarHBondContact CE-OE2 3.19Å; M1-E125 PolarHBondContact N-OE1 3.14Å
2S87.5Confident95.9Very high43 Ų4353 Ų5330%0.30125%0.253SS..BIsolated β-bridgetrans-81.3152.7-178.557.80000113.5
3I97.4Very high96.1Very high4 Ų449.7 Ų49.72%0.02124%0.238CC..  trans-69.2128.4172.5-59168000109.9V6 L24 L77 V78 V84 I90 V118I3-V6 HydrophobicContact CG2-CG2 3.58Å; I3-L24 HydrophobicContact CD1-CD1 4.03Å; I3-L24 HydrophobicContact CG1-CD1 4.12Å; I3-L24 HydrophobicContact CG1-CD2 4.38Å; I3-L24 HydrophobicContact CG2-CD1 4.3Å; I3-L24 HydrophobicContact CG2-CD2 4.45Å; I3-L24 HydrophobicContact CG2-CG 4.1Å; I3-L77 HydrophobicContact CD1-CB 4.05Å; I3-L77 HydrophobicContact CD1-CD1 4.28Å; I3-V78 HydrophobicContact CG2-CG2 4.17Å; I3-V84 HydrophobicContact CD1-CG1 4.37Å; I3-V84 HydrophobicContact CG1-CG1 3.61Å; I3-I90 HydrophobicContact CD1-CD1 4.29Å; I3-V118 HydrophobicContact CD1-CG2 4.39Å
4L97.8Very high96.3Very high99 Ų9947.9 Ų47.952%0.51823%0.234SC..  trans-95-37.9179.4-60.5-179.6000112.5F25L4-F25 WeakPolarHBondContact CB-O 2.97Å; L4-F25 PolarHBondContact N-O 3.38Å
5K98.3Very high96.3Very high116 Ų11649.1 Ų49.150%0.50423%0.234SC..EExtended strand (participates in β ladder)trans-155.8146.8179.6-179.3178.8178.5-178.30109.2F25K5-F25 HydrophobicContact CB-CB 4.04Å; K5-F25 HydrophobicContact CB-CD2 3.84Å; K5-F25 HydrophobicContact CB-CG 4.18Å; K5-F25 HydrophobicContact CD-CD2 4.13Å; K5-F25 HydrophobicContact CD-CE2 4.24Å; K5-F25 HydrophobicContact CG-CD2 4.01Å; K5-F25 HydrophobicContact CG-CE2 4.44Å; K5-F25 PolarHBondContact O-N 2.96Å
6V98.8Very high96.4Very high8 Ų848.9 Ų48.95%0.04825%0.249CC..EExtended strand (participates in β ladder)trans-126.6137.6165.4-179.60000106.8I3 V22 D23 L24 I69 A74 V114I3-V6 HydrophobicContact CG2-CG2 3.58Å; V6-V22 HydrophobicContact CG1-CG1 3.65Å; V6-D23 CarbonylContact C-O 3.59Å; V6-D23 WeakPolarHBondContact CA-O 3.44Å; V6-L24 HydrophobicContact CG2-CD1 4.22Å; V6-L24 HydrophobicContact CG2-CG 4.19Å; V6-I69 HydrophobicContact CG1-CG2 3.93Å; V6-A74 HydrophobicContact CB-CB 3.66Å; V6-A74 HydrophobicContact CG1-CB 4.24Å; V6-V114 HydrophobicContact CG1-CG2 4.27Å
7H98.8Very high96.5Very high68 Ų6847.4 Ų47.432%0.31524%0.242SC..EExtended strand (participates in β ladder)trans-142.9127.1176.917857000110.2R9 D23 N70H7-R9 PolarHBondContact CD2-NH2 2.76Å; H7-D23 PolarHBondContact N-O 3.01Å; H7-D23 PolarHBondContact O-N 3.5Å; H7-N70 WeakPolarHBondContact CA-OD1 3.28Å; H7-N70 PolarHBondContact ND1-OD1 2.7Å; H7-N70 VanDerWaalsContact ND1-OD1 3.12Å
8A98.9Very high96.6Very high2 Ų244.8 Ų44.82%0.01723%0.229CC..EExtended strand (participates in β ladder)trans-105.7151.6175.100000112E21 V22 V66 I69 N70A8-E21 CarbonylContact C-O 3.59Å; A8-E21 WeakPolarHBondContact CA-O 3.48Å; A8-V22 HydrophobicContact CB-CG2 4.14Å; A8-V66 HydrophobicContact CB-CG1 4.13Å; A8-V66 WeakPolarHBondContact O-CG1 3.33Å; A8-I69 HydrophobicContact CB-CB 3.68Å; A8-I69 HydrophobicContact CB-CD1 3.45Å; A8-I69 VanDerWaalsContact CB-CD1 3.45Å; A8-I69 HydrophobicContact CB-CG1 4.2Å; A8-I69 HydrophobicContact CB-CG2 3.67Å; A8-N70 PolarHBondContact N-OD1 3.33Å; A8-N70 PolarHBondContact O-ND2 3.4Å
9R98.9Very high96.8Very high68 Ų6842.5 Ų42.526%0.25722%0.217SC..EExtended strand (participates in β ladder)trans-141.2165.4172.766.5-175.966.680.7-0110.7H7 I11 E21 D23H7-R9 PolarHBondContact CD2-NH2 2.76Å; R9-I11 HydrophobicContact CG-CG2 4.1Å; R9-E21 WeakPolarHBondContact CD-OE1 3.35Å; R9-E21 HydrophobicContact CG-CB 4Å; R9-E21 IonicContact CZ-OE1 3.62Å; R9-E21 PolarHBondContact N-O 3.43Å; R9-E21 IonicContact NE-OE1 2.55Å; R9-E21 IonicContact NH1-OE1 2.65Å; R9-E21 PolarHBondContact NH1-OE1 2.96Å; R9-E21 PolarHBondContact O-N 2.9Å; R9-D23 IonicContact CZ-OD1 3.65Å; R9-D23 IonicContact CZ-OD2 3.44Å; R9-D23 VanDerWaalsContact CZ-OD2 3.28Å; R9-D23 IonicContact NH1-OD1 3.3Å; R9-D23 PolarHBondContact NH1-OD1 3.23Å; R9-D23 IonicContact NH1-OD2 3.59Å; R9-D23 PolarHBondContact NH1-OD2 2.69Å; R9-D23 IonicContact NH2-OD2 3Å; R9-D23 PolarHBondContact NH2-OD2 2.73Å
10E98.8Very high96.9Very high48 Ų4840.4 Ų40.422%0.22421%0.206CC..EExtended strand (participates in β ladder)trans-92129.3171-174.7175.873.700109.2P18 T19 R56 Y57 V62 V66E10-P18 HydrophobicContact CG-CB 3.7Å; E10-P18 WeakPolarHBondContact OE2-CB 3.26Å; E10-T19 WeakPolarHBondContact CA-O 3.05Å; E10-R56 IonicContact OE1-CZ 3.73Å; E10-R56 VanDerWaalsContact OE1-CZ 3.3Å; E10-R56 IonicContact OE1-NH1 3.11Å; E10-R56 PolarHBondContact OE1-NH1 3.08Å; E10-R56 VanDerWaalsContact OE1-NH1 3.16Å; E10-R56 IonicContact OE1-NH2 2.84Å; E10-R56 PolarHBondContact OE1-NH2 2.97Å; E10-R56 IonicContact OE2-CZ 3.56Å; E10-R56 IonicContact OE2-NH1 2.61Å; E10-R56 PolarHBondContact OE2-NH1 3.05Å; E10-R56 IonicContact OE2-NH2 2.87Å; E10-Y57 WeakPolarHBondContact OE1-CE2 3.26Å; E10-V62 HydrophobicContact CB-CG2 4.12Å; E10-V62 HydrophobicContact CG-CG2 3.59Å; E10-V62 WeakPolarHBondContact OE2-CG2 3.31Å; E10-V62 PolarHBondContact OE2-N 3.06Å; E10-V66 HydrophobicContact CB-CG2 4.47Å
11I98.8Very high97Very high25 Ų2539.1 Ų39.113%0.12820%0.199CC..EExtended strand (participates in β ladder)trans-123.9-174.9171.366.9163.6000109.3R9 P18 T19 E21 A34 T376R9-I11 HydrophobicContact CG-CG2 4.1Å; I11-P18 CarbonylContact O-C 3.52Å; I11-P18 VanDerWaalsContact O-CA 3.25Å; I11-P18 WeakPolarHBondContact O-CA 3.28Å; I11-T19 HydrophobicContact CD1-CG2 4.23Å; I11-T19 HydrophobicContact CG1-CG2 3.72Å; I11-T19 PolarHBondContact N-O 3.48Å; I11-T19 PolarHBondContact O-N 3.18Å; I11-E21 HydrophobicContact CD1-CB 3.99Å; I11-E21 HydrophobicContact CG1-CB 4.03Å; I11-E21 HydrophobicContact CG2-CB 3.78Å; I11-E21 HydrophobicContact CG2-CG 4.5Å; I11-A34 HydrophobicContact CD1-CB 3.74Å; I11-T376 HydrophobicContact CD1-CG2 4.46Å
12F98.7Very high97.9Very high103 Ų10336.6 Ų36.645%0.45219%0.187SC..EExtended strand (participates in β ladder)trans-111.1139.4176.4-67.1-84.4000111.9G16 N17 P18 Y57F12-G16 WeakPolarHBondContact CD1-O 3.37Å; F12-N17 CarbonylContact C-O 3.55Å; F12-N17 WeakPolarHBondContact CA-O 3.44Å; F12-P18 HydrophobicContact CE1-CG 4.41Å; F12-Y57 HydrophobicContact CE1-CD1 4.19Å; F12-Y57 AromaticContact CE1-CE1 3.67Å; F12-Y57 HydrophobicContact CE1-CE1 3.67Å; F12-Y57 AromaticContact CZ-CE1 3.67Å; F12-Y57 HydrophobicContact CZ-CE1 3.67Å; F12-Y57 AromaticContact CZ-CZ 3.78Å; F12-Y57 WeakPolarHBondContact CZ-OH 3.48Å
13D98.6Very high98.5Very high10 Ų1034.8 Ų34.85%0.05317%0.174CC..  trans-77.8177.4169.279.13.4000111.7R15 G16 N17 T19 E375D13-R15 PolarHBondContact O-N 2.99Å; D13-R15 WeakPolarHBondContact OD1-CA 3.33Å; D13-R15 WeakPolarHBondContact OD1-CB 3.44Å; D13-R15 PolarHBondContact OD1-N 3.09Å; D13-R15 IonicContact OD2-NE 2.69Å; D13-R15 IonicContact OD2-NH2 3.75Å; D13-G16 PolarHBondContact O-N 3.17Å; D13-G16 PolarHBondContact OD1-N 3.06Å; D13-G16 VanDerWaalsContact OD1-N 3.08Å; D13-N17 PolarHBondContact N-O 3.31Å; D13-N17 PolarHBondContact OD1-N 3.11Å; D13-T19 HydrophobicContact CB-CG2 4.32Å; D13-E375 CarbonylContact C-O 3.54Å; D13-E375 WeakPolarHBondContact CA-O 3.36Å
14S98.1Very high98.5Very high25 Ų2534.6 Ų34.618%0.17517%0.173CC..THydrogen-bonded Turntrans-64.5-11.5-178.263.70000114.6S373 E375 R400 E402S14-S373 PolarHBondContact OG-O 3.32Å; S14-E375 WeakPolarHBondContact CB-O 3.44Å; S14-E375 PolarHBondContact N-O 3.1Å; S14-E375 PolarHBondContact OG-N 3.2Å; S14-E375 PolarHBondContact OG-O 3.15Å; S14-R400 PolarHBondContact O-NH2 3.19Å; S14-E402 VanDerWaalsContact CB-CG 3.48Å
15R96.6Very high98.6Very high65 Ų6532.6 Ų32.625%0.24516%0.16CC..THydrogen-bonded Turntrans-103.73.2176-61.2178.3-61.7175.5-4.8111.8D13 N17 S37 G38 A39 D209D13-R15 PolarHBondContact O-N 2.99Å; D13-R15 WeakPolarHBondContact OD1-CA 3.33Å; D13-R15 WeakPolarHBondContact OD1-CB 3.44Å; D13-R15 PolarHBondContact OD1-N 3.09Å; D13-R15 IonicContact OD2-NE 2.69Å; D13-R15 IonicContact OD2-NH2 3.75Å; R15-N17 VanDerWaalsContact C-N 3.32Å; R15-N17 WeakPolarHBondContact CB-ND2 3.06Å; R15-S37 PolarHBondContact NH2-O 3.48Å; R15-G38 PolarHBondContact NH1-O 3.14Å; R15-G38 PolarHBondContact NH2-O 3.4Å; R15-A39 VanDerWaalsContact NH1-CB 3.25Å; R15-D209 WeakPolarHBondContact CD-OD2 3.44Å
16G97.8Very high98.6Very high46 Ų4627.5 Ų27.547%0.47414%0.139SC..SBendtrans75.318.3-178.200000113.9F12 D13F12-G16 WeakPolarHBondContact CD1-O 3.37Å; D13-G16 PolarHBondContact O-N 3.17Å; D13-G16 PolarHBondContact OD1-N 3.06Å; D13-G16 VanDerWaalsContact OD1-N 3.08Å
17N98.4Very high98.5Very high24 Ų2431.3 Ų31.313%0.12817%0.166CC..  trans-91.8148.7171.7-55.8-70000110.2F12 D13 R15 K60F12-N17 CarbonylContact C-O 3.55Å; F12-N17 WeakPolarHBondContact CA-O 3.44Å; D13-N17 PolarHBondContact N-O 3.31Å; D13-N17 PolarHBondContact OD1-N 3.11Å; R15-N17 VanDerWaalsContact C-N 3.32Å; R15-N17 WeakPolarHBondContact CB-ND2 3.06Å; N17-K60 HydrophobicContact CB-CD 4.3Å; N17-K60 WeakPolarHBondContact OD1-CD 3.3Å; N17-K60 PolarHBondContact OD1-NZ 3.06Å
18P98.6Very high98.5Very high1 Ų134 Ų341%0.00618%0.176CC..EExtended strand (participates in β ladder)trans-58146.2173.9-25.834.9000113.2E10 I11 F12 R50 Y57 V62E10-P18 HydrophobicContact CG-CB 3.7Å; E10-P18 WeakPolarHBondContact OE2-CB 3.26Å; I11-P18 CarbonylContact O-C 3.52Å; I11-P18 VanDerWaalsContact O-CA 3.25Å; I11-P18 WeakPolarHBondContact O-CA 3.28Å; F12-P18 HydrophobicContact CE1-CG 4.41Å; P18-R50 PolarHBondContact O-NH1 2.96Å; P18-Y57 HydrophobicContact CB-CD2 4.44Å; P18-Y57 HydrophobicContact CG-CD1 4.03Å; P18-Y57 HydrophobicContact CG-CD2 3.31Å; P18-Y57 HydrophobicContact CG-CE1 4.5Å; P18-Y57 HydrophobicContact CG-CE2 3.82Å; P18-Y57 HydrophobicContact CG-CG 3.42Å; P18-Y57 VanDerWaalsContact CG-CG 3.42Å; P18-V62 HydrophobicContact CB-CG2 4.2Å
19T98.9Very high98.4Very high0 Ų035.4 Ų35.40%019%0.192CC..EExtended strand (participates in β ladder)trans-149.3170.5167.7-165.30000111.4E10 I11 D13 V35 T376E10-T19 WeakPolarHBondContact CA-O 3.05Å; I11-T19 HydrophobicContact CD1-CG2 4.23Å; I11-T19 HydrophobicContact CG1-CG2 3.72Å; I11-T19 PolarHBondContact N-O 3.48Å; I11-T19 PolarHBondContact O-N 3.18Å; D13-T19 HydrophobicContact CB-CG2 4.32Å; T19-V35 WeakPolarHBondContact CB-O 3.48Å; T19-V35 WeakPolarHBondContact CG2-O 3.13Å; T19-V35 PolarHBondContact OG1-O 3.18Å; T19-T376 HydrophobicContact CG2-CG2 3.92Å
20V98.9Very high98.4Very high0 Ų035.9 Ų35.90%020%0.199CC..EExtended strand (participates in β ladder)trans-87.3131.6-176176.40000110.7V22 A34 V35 V62 A65 V66 I69 N109V20-V22 HydrophobicContact CG1-CG2 3.99Å; V20-A34 WeakPolarHBondContact O-CA 3.47Å; V20-V35 HydrophobicContact CB-CB 4.49Å; V20-V35 HydrophobicContact CB-CG2 4.36Å; V20-V35 PolarHBondContact O-N 3.28Å; V20-V62 HydrophobicContact CG2-CB 4.06Å; V20-V62 HydrophobicContact CG2-CG2 4.05Å; V20-A65 HydrophobicContact CG2-CB 3.91Å; V20-V66 HydrophobicContact CG2-CG2 4.3Å; V20-I69 HydrophobicContact CG1-CD1 3.5Å; V20-N109 HydrophobicContact CG2-CB 4.3Å
21E98.9Very high98.4Very high14 Ų1434.5 Ų34.57%0.06519%0.192CC..EExtended strand (participates in β ladder)trans-119.4140.4163.8-176.5-175.784.900110A8 R9 I11 R32 A33 A34A8-E21 CarbonylContact C-O 3.59Å; A8-E21 WeakPolarHBondContact CA-O 3.48Å; R9-E21 WeakPolarHBondContact CD-OE1 3.35Å; R9-E21 HydrophobicContact CG-CB 4Å; R9-E21 IonicContact CZ-OE1 3.62Å; R9-E21 PolarHBondContact N-O 3.43Å; R9-E21 IonicContact NE-OE1 2.55Å; R9-E21 IonicContact NH1-OE1 2.65Å; R9-E21 PolarHBondContact NH1-OE1 2.96Å; R9-E21 PolarHBondContact O-N 2.9Å; I11-E21 HydrophobicContact CD1-CB 3.99Å; I11-E21 HydrophobicContact CG1-CB 4.03Å; I11-E21 HydrophobicContact CG2-CB 3.78Å; I11-E21 HydrophobicContact CG2-CG 4.5Å; E21-R32 VanDerWaalsContact CD-CD 3.43Å; E21-R32 HydrophobicContact CG-CG 3.76Å; E21-R32 IonicContact OE1-CZ 3.97Å; E21-R32 IonicContact OE1-NE 2.76Å; E21-R32 PolarHBondContact OE1-NE 2.95Å; E21-R32 VanDerWaalsContact OE2-CD 3.29Å; E21-R32 WeakPolarHBondContact OE2-CD 3.46Å; E21-R32 IonicContact OE2-NE 2.65Å; E21-A33 CarbonylContact C-O 3.34Å; E21-A33 WeakPolarHBondContact CA-O 3.48Å; E21-A34 HydrophobicContact CB-CB 4.42Å; E21-A34 HydrophobicContact CG-CB 4.44Å
22V98.9Very high98.4Very high0 Ų038.6 Ų38.60%021%0.206CC..EExtended strand (participates in β ladder)trans-124.2128.1179.6-179.20000110.5V6 A8 V20 R32 A33 I69 V114 A117V6-V22 HydrophobicContact CG1-CG1 3.65Å; A8-V22 HydrophobicContact CB-CG2 4.14Å; V20-V22 HydrophobicContact CG1-CG2 3.99Å; V22-R32 CarbonylContact O-C 3.56Å; V22-R32 VanDerWaalsContact O-CA 3.29Å; V22-R32 WeakPolarHBondContact O-CA 3.45Å; V22-A33 PolarHBondContact N-O 2.85Å; V22-A33 PolarHBondContact O-N 3.28Å; V22-I69 HydrophobicContact CG2-CD1 3.77Å; V22-V114 HydrophobicContact CG1-CG2 4.09Å; V22-V114 HydrophobicContact CG2-CG2 4.22Å; V22-A117 HydrophobicContact CG1-CB 4.26Å
23D98.9Very high98.4Very high4 Ų433.7 Ų33.72%0.02119%0.185CC..EExtended strand (participates in β ladder)trans-98.7125163.1-71.3-4000110V6 H7 R9 F25 L30 F31 R32V6-D23 CarbonylContact C-O 3.59Å; V6-D23 WeakPolarHBondContact CA-O 3.44Å; H7-D23 PolarHBondContact N-O 3.01Å; H7-D23 PolarHBondContact O-N 3.5Å; R9-D23 IonicContact CZ-OD1 3.65Å; R9-D23 IonicContact CZ-OD2 3.44Å; R9-D23 VanDerWaalsContact CZ-OD2 3.28Å; R9-D23 IonicContact NH1-OD1 3.3Å; R9-D23 PolarHBondContact NH1-OD1 3.23Å; R9-D23 IonicContact NH1-OD2 3.59Å; R9-D23 PolarHBondContact NH1-OD2 2.69Å; R9-D23 IonicContact NH2-OD2 3Å; R9-D23 PolarHBondContact NH2-OD2 2.73Å; D23-F25 HydrophobicContact CB-CD2 4.44Å; D23-F25 HydrophobicContact CB-CE2 3.63Å; D23-F25 HydrophobicContact CB-CZ 4.08Å; D23-L30 HydrophobicContact CB-CD1 4.37Å; D23-L30 HydrophobicContact CB-CD2 4.45Å; D23-L30 HydrophobicContact CB-CG 4.2Å; D23-F31 CarbonylContact C-O 3.53Å; D23-F31 WeakPolarHBondContact CA-O 3.42Å; D23-R32 WeakPolarHBondContact OD1-CG 3.43Å; D23-R32 IonicContact OD1-CZ 3.52Å; D23-R32 IonicContact OD1-NE 2.86Å; D23-R32 PolarHBondContact OD1-NE 3.13Å; D23-R32 IonicContact OD1-NH2 2.71Å; D23-R32 PolarHBondContact OD1-NH2 2.89Å; D23-R32 IonicContact OD2-CZ 2.94Å; D23-R32 IonicContact OD2-NE 3.36Å; D23-R32 IonicContact OD2-NH2 2.76Å; D23-R32 PolarHBondContact OD2-NH2 3.44Å
24L98.9Very high98.4Very high0 Ų033.5 Ų33.50%018%0.184CC..EExtended strand (participates in β ladder)trans-110.9133.4170.3-173.8151.5000109.3I3 V6 T26 L30 F31 V84 A117 V118 A121I3-L24 HydrophobicContact CD1-CD1 4.03Å; I3-L24 HydrophobicContact CG1-CD1 4.12Å; I3-L24 HydrophobicContact CG1-CD2 4.38Å; I3-L24 HydrophobicContact CG2-CD1 4.3Å; I3-L24 HydrophobicContact CG2-CD2 4.45Å; I3-L24 HydrophobicContact CG2-CG 4.1Å; V6-L24 HydrophobicContact CG2-CD1 4.22Å; V6-L24 HydrophobicContact CG2-CG 4.19Å; L24-T26 HydrophobicContact CD2-CG2 3.6Å; L24-L30 CarbonylContact O-C 3.54Å; L24-L30 WeakPolarHBondContact O-CA 3.34Å; L24-F31 HydrophobicContact CD2-CD2 4.2Å; L24-F31 PolarHBondContact N-O 2.85Å; L24-F31 WeakPolarHBondContact O-CD2 3.25Å; L24-F31 PolarHBondContact O-N 2.75Å; L24-V84 HydrophobicContact CD2-CG1 4.17Å; L24-A117 HydrophobicContact CB-CB 3.85Å; L24-V118 HydrophobicContact CD1-CB 4.35Å; L24-V118 HydrophobicContact CD1-CG2 3.42Å; L24-V118 VanDerWaalsContact CD1-CG2 3.42Å; L24-A121 HydrophobicContact CD2-CB 3.78Å
25F98.7Very high98.4Very high58 Ų5832.4 Ų32.425%0.25418%0.176SC..EExtended strand (participates in β ladder)trans-112.4130.7-178.9-60.9-102.8000110.3L4 K5 D23 G29 L30L4-F25 WeakPolarHBondContact CB-O 2.97Å; L4-F25 PolarHBondContact N-O 3.38Å; K5-F25 HydrophobicContact CB-CB 4.04Å; K5-F25 HydrophobicContact CB-CD2 3.84Å; K5-F25 HydrophobicContact CB-CG 4.18Å; K5-F25 HydrophobicContact CD-CD2 4.13Å; K5-F25 HydrophobicContact CD-CE2 4.24Å; K5-F25 HydrophobicContact CG-CD2 4.01Å; K5-F25 HydrophobicContact CG-CE2 4.44Å; K5-F25 PolarHBondContact O-N 2.96Å; D23-F25 HydrophobicContact CB-CD2 4.44Å; D23-F25 HydrophobicContact CB-CE2 3.63Å; D23-F25 HydrophobicContact CB-CZ 4.08Å; F25-G29 WeakPolarHBondContact CA-O 3.32Å; F25-L30 HydrophobicContact CD1-CB 4.2Å; F25-L30 HydrophobicContact CD1-CG 4.48Å; F25-L30 HydrophobicContact CE1-CB 4.02Å; F25-L30 HydrophobicContact CE1-CD1 3.63Å; F25-L30 HydrophobicContact CE1-CG 3.98Å; F25-L30 HydrophobicContact CZ-CD1 3.61Å; F25-L30 HydrophobicContact CZ-CG 4.06Å
26T98.4Very high98.5Very high8 Ų829.9 Ų29.95%0.04917%0.168CC..EExtended strand (participates in β ladder)trans-124.2-178.5165.178.80000108.9L24 K28 G29 F31 V84 A121L24-T26 HydrophobicContact CD2-CG2 3.6Å; T26-K28 PolarHBondContact O-N 3.28Å; T26-K28 WeakPolarHBondContact OG1-CB 3.35Å; T26-K28 PolarHBondContact OG1-N 3.49Å; T26-G29 PolarHBondContact N-O 3.13Å; T26-G29 PolarHBondContact O-N 3.24Å; T26-F31 HydrophobicContact CG2-CD2 4.33Å; T26-F31 HydrophobicContact CG2-CE2 3.98Å; T26-F31 WeakPolarHBondContact OG1-CE2 3.43Å; T26-V84 HydrophobicContact CG2-CG1 3.9Å; T26-A121 HydrophobicContact CG2-CB 4.18Å
27S97.3Very high98.4Very high88 Ų8827.9 Ų27.962%0.61515%0.147SC*.THydrogen-bonded Turntrans-71.1-5.3172.570.10000113.6M1M1-S27 WeakPolarHBondContact CE-OG 3.37Å; M1-S27 PolarHBondContact SD-OG 3.25Å
28K97.8Very high97.8Very high124 Ų12427.1 Ų27.154%0.53915%0.145SC..THydrogen-bonded Turntrans-88.2-10.1171.3-63-66.6-172.4173.40113.8M1 T26 F31 V124M1-K28 HydrophobicContact CE-CD 4.41Å; M1-K28 HydrophobicContact CE-CG 4Å; M1-K28 HydrophobicContact SD-CG 3.88Å; T26-K28 PolarHBondContact O-N 3.28Å; T26-K28 WeakPolarHBondContact OG1-CB 3.35Å; T26-K28 PolarHBondContact OG1-N 3.49Å; K28-F31 HydrophobicContact CB-CE2 4.47Å; K28-F31 HydrophobicContact CB-CZ 3.98Å; K28-V124 HydrophobicContact CB-CG1 4.01Å; K28-V124 HydrophobicContact CG-CG1 4.45Å
29G97.9Very high96.7Very high33 Ų3328.9 Ų28.934%0.3416%0.16SC..EExtended strand (participates in β ladder)trans130.4-155.3176.500000113.8F25 T26 F31F25-G29 WeakPolarHBondContact CA-O 3.32Å; T26-G29 PolarHBondContact N-O 3.13Å; T26-G29 PolarHBondContact O-N 3.24Å; G29-F31 WeakPolarHBondContact O-CE2 3.02Å
30L98.4Very high95.2Very high77 Ų7729.1 Ų29.140%0.40316%0.161SC..EExtended strand (participates in β ladder)trans-102.7132-178.4179.7163.7000109.7D23 L24 F25 R32D23-L30 HydrophobicContact CB-CD1 4.37Å; D23-L30 HydrophobicContact CB-CD2 4.45Å; D23-L30 HydrophobicContact CB-CG 4.2Å; L24-L30 CarbonylContact O-C 3.54Å; L24-L30 WeakPolarHBondContact O-CA 3.34Å; F25-L30 HydrophobicContact CD1-CB 4.2Å; F25-L30 HydrophobicContact CD1-CG 4.48Å; F25-L30 HydrophobicContact CE1-CB 4.02Å; F25-L30 HydrophobicContact CE1-CD1 3.63Å; F25-L30 HydrophobicContact CE1-CG 3.98Å; F25-L30 HydrophobicContact CZ-CD1 3.61Å; F25-L30 HydrophobicContact CZ-CG 4.06Å; L30-R32 HydrophobicContact CD2-CB 3.99Å
31F98.8Very high94.3Very high19 Ų1932.5 Ų32.58%0.08318%0.182CC..EExtended strand (participates in β ladder)trans-121.4122.2176.8-53.6-81.8000109.1D23 L24 T26 K28 G29 K120 A121 V124D23-F31 CarbonylContact C-O 3.53Å; D23-F31 WeakPolarHBondContact CA-O 3.42Å; L24-F31 HydrophobicContact CD2-CD2 4.2Å; L24-F31 PolarHBondContact N-O 2.85Å; L24-F31 WeakPolarHBondContact O-CD2 3.25Å; L24-F31 PolarHBondContact O-N 2.75Å; T26-F31 HydrophobicContact CG2-CD2 4.33Å; T26-F31 HydrophobicContact CG2-CE2 3.98Å; T26-F31 WeakPolarHBondContact OG1-CE2 3.43Å; K28-F31 HydrophobicContact CB-CE2 4.47Å; K28-F31 HydrophobicContact CB-CZ 3.98Å; G29-F31 WeakPolarHBondContact O-CE2 3.02Å; F31-K120 HydrophobicContact CB-CB 4.22Å; F31-K120 HydrophobicContact CD1-CB 4.39Å; F31-A121 HydrophobicContact CB-CB 4.17Å; F31-A121 HydrophobicContact CD1-CB 4.11Å; F31-A121 HydrophobicContact CD2-CB 3.42Å; F31-A121 VanDerWaalsContact CD2-CB 3.42Å; F31-A121 HydrophobicContact CE1-CB 4.45Å; F31-A121 HydrophobicContact CE2-CB 3.82Å; F31-A121 HydrophobicContact CG-CB 3.59Å; F31-A121 HydrophobicContact CZ-CB 4.31Å; F31-V124 HydrophobicContact CD1-CG2 4.43Å; F31-V124 HydrophobicContact CE1-CB 3.54Å; F31-V124 HydrophobicContact CE1-CG1 3.92Å; F31-V124 HydrophobicContact CE1-CG2 3.59Å; F31-V124 HydrophobicContact CZ-CB 3.91Å; F31-V124 HydrophobicContact CZ-CG1 3.94Å; F31-V124 HydrophobicContact CZ-CG2 4.42Å
32R98.9Very high93.4Very high112 Ų11232 Ų3242%0.42318%0.181SC..EExtended strand (participates in β ladder)trans-113.8136.5-172.1-179.3170.6-72168.34.4111.3E21 V22 D23 L30 K120E21-R32 VanDerWaalsContact CD-CD 3.43Å; E21-R32 HydrophobicContact CG-CG 3.76Å; E21-R32 IonicContact OE1-CZ 3.97Å; E21-R32 IonicContact OE1-NE 2.76Å; E21-R32 PolarHBondContact OE1-NE 2.95Å; E21-R32 VanDerWaalsContact OE2-CD 3.29Å; E21-R32 WeakPolarHBondContact OE2-CD 3.46Å; E21-R32 IonicContact OE2-NE 2.65Å; V22-R32 CarbonylContact O-C 3.56Å; V22-R32 VanDerWaalsContact O-CA 3.29Å; V22-R32 WeakPolarHBondContact O-CA 3.45Å; D23-R32 WeakPolarHBondContact OD1-CG 3.43Å; D23-R32 IonicContact OD1-CZ 3.52Å; D23-R32 IonicContact OD1-NE 2.86Å; D23-R32 PolarHBondContact OD1-NE 3.13Å; D23-R32 IonicContact OD1-NH2 2.71Å; D23-R32 PolarHBondContact OD1-NH2 2.89Å; D23-R32 IonicContact OD2-CZ 2.94Å; D23-R32 IonicContact OD2-NE 3.36Å; D23-R32 IonicContact OD2-NH2 2.76Å; D23-R32 PolarHBondContact OD2-NH2 3.44Å; L30-R32 HydrophobicContact CD2-CB 3.99Å; R32-K120 WeakPolarHBondContact O-CD 3.45Å; R32-K120 WeakPolarHBondContact O-CE 3.47Å; R32-K120 PolarHBondContact O-NZ 3.09Å
33A98.8Very high92.9Very high0 Ų037.6 Ų37.60%021%0.21CC..EExtended strand (participates in β ladder)trans-138.5143.816900000112.3E21 V22 L116 A117 D378E21-A33 CarbonylContact C-O 3.34Å; E21-A33 WeakPolarHBondContact CA-O 3.48Å; V22-A33 PolarHBondContact N-O 2.85Å; V22-A33 PolarHBondContact O-N 3.28Å; A33-L116 HydrophobicContact CB-CB 3.41Å; A33-L116 VanDerWaalsContact CB-CB 3.41Å; A33-L116 HydrophobicContact CB-CD1 4.32Å; A33-A117 HydrophobicContact CB-CB 4.12Å; A33-D378 WeakPolarHBondContact CA-OD2 3.38Å
34A98.8Very high92.7Very high5 Ų541.6 Ų41.64%0.04123%0.225CC..EExtended strand (participates in β ladder)trans-117.9151174.300000111.5I11 V20 E21 T376 D378I11-A34 HydrophobicContact CD1-CB 3.74Å; V20-A34 WeakPolarHBondContact O-CA 3.47Å; E21-A34 HydrophobicContact CB-CB 4.42Å; E21-A34 HydrophobicContact CG-CB 4.44Å; A34-T376 HydrophobicContact CB-CG2 3.87Å; A34-D378 HydrophobicContact CB-CB 4.32Å; A34-D378 PolarHBondContact N-OD2 3.31Å
35V98.8Very high92.5Very high2 Ų242.8 Ų42.81%0.01223%0.231CC..  trans-102.7127.3-1741780000110.5T19 V20 N109 L112 G113 N345T19-V35 WeakPolarHBondContact CB-O 3.48Å; T19-V35 WeakPolarHBondContact CG2-O 3.13Å; T19-V35 PolarHBondContact OG1-O 3.18Å; V20-V35 HydrophobicContact CB-CB 4.49Å; V20-V35 HydrophobicContact CB-CG2 4.36Å; V20-V35 PolarHBondContact O-N 3.28Å; V35-N109 HydrophobicContact CG1-CB 3.9Å; V35-N109 WeakPolarHBondContact CG2-O 3.39Å; V35-L112 HydrophobicContact CG1-CD2 3.77Å; V35-L112 HydrophobicContact CG2-CB 4.33Å; V35-L112 HydrophobicContact CG2-CD2 4.27Å; V35-L112 HydrophobicContact CG2-CG 4.42Å; V35-G113 VanDerWaalsContact CG2-CA 3.49Å; V35-N345 HydrophobicContact CG1-CB 4.5Å
36P98.3Very high92.3Very high12 Ų1240.5 Ų40.58%0.07822%0.223CC..  trans-77.4166.6174.434.5-37.6000111.7N345 R372 G374P36-N345 HydrophobicContact CG-CB 4.35Å; P36-N345 PolarHBondContact O-ND2 3.14Å; P36-N345 VanDerWaalsContact O-ND2 3.17Å; P36-R372 HydrophobicContact CB-CB 4.01Å; P36-R372 HydrophobicContact CB-CG 3.84Å; P36-R372 HydrophobicContact CG-CG 3.99Å; P36-G374 CarbonylContact C-O 3.57Å; P36-G374 WeakPolarHBondContact CA-O 3.18Å; P36-G374 WeakPolarHBondContact CB-O 3.21Å
37S95.8Very high92.3Very high4 Ų443.5 Ų43.53%0.02824%0.238CC..BIsolated β-bridgetrans-136.6142.5179.5-178.30000111.9R15 E48 R50 R372 G374R15-S37 PolarHBondContact NH2-O 3.48Å; S37-E48 WeakPolarHBondContact CB-OE2 3.34Å; S37-E48 VanDerWaalsContact OG-CD 3.29Å; S37-E48 PolarHBondContact OG-OE1 3.02Å; S37-E48 VanDerWaalsContact OG-OE1 3.09Å; S37-E48 PolarHBondContact OG-OE2 2.85Å; S37-R50 PolarHBondContact OG-NH2 3.28Å; S37-R372 WeakPolarHBondContact O-CB 3.35Å; S37-G374 PolarHBondContact N-O 2.63Å; S37-G374 CarbonylContact O-C 3.46Å; S37-G374 WeakPolarHBondContact O-CA 3.4Å; S37-G374 PolarHBondContact O-N 2.94Å
38G84.7Confident92.3Very high9 Ų941.3 Ų41.39%0.09322%0.218CC..  trans-82.7167.7-179.500000115.3R15R15-G38 PolarHBondContact NH1-O 3.14Å; R15-G38 PolarHBondContact NH2-O 3.4Å
39A76.3Confident92.3Very high38 Ų3836.7 Ų36.731%0.31420%0.199SC..SBendtrans-108.9-62.6166.400000109.4R15 S373R15-A39 VanDerWaalsContact NH1-CB 3.25Å; A39-S373 WeakPolarHBondContact CB-OG 3.4Å; A39-S373 PolarHBondContact N-OG 2.79Å
40S68.1Low92.3Very high4 Ų436.7 Ų36.73%0.02819%0.189CC..SBendtrans-78.3119.9160.457.90000108Q166 R372S40-Q166 PolarHBondContact OG-NE2 3.06Å; S40-R372 PolarHBondContact O-NH2 3.02Å
41T79.2Confident92.3Very high72 Ų7233.6 Ų33.644%0.44217%0.173SC..  trans-125.2116.3179.155.10000108.2
42G79.1Confident92.2Very high4 Ų438.7 Ų38.74%0.04120%0.201CC..  trans-54.4143.8170.900000111.3Y44 E45 Q298 D319G42-Y44 PolarHBondContact O-N 3.04Å; G42-E45 PolarHBondContact N-OE1 3.08Å; G42-E45 WeakPolarHBondContact O-CG 3.32Å; G42-E45 PolarHBondContact O-N 3.31Å; G42-Q298 VanDerWaalsContact CA-OE1 3.3Å; G42-D319 VanDerWaalsContact CA-OD1 3.29Å; G42-D319 WeakPolarHBondContact CA-OD1 3.49Å; G42-D319 PolarHBondContact N-OD1 3.1Å
43I89.3Confident92.1Very high116 Ų11636.8 Ų36.860%0.59520%0.199SC*.THydrogen-bonded Turntrans-68.5-12.1-173.666.4-177000113
44Y93.8Very high92Very high88 Ų8845.6 Ų45.635%0.34524%0.237SC..THydrogen-bonded Turntrans-101.42.2-178.4-59.1-72.6000113.7G42 Q298 D299 R327G42-Y44 PolarHBondContact O-N 3.04Å; Y44-Q298 HydrophobicContact CE2-CG 4.4Å; Y44-D299 WeakPolarHBondContact CE2-OD1 3.47Å; Y44-D299 WeakPolarHBondContact CE2-OD2 3.22Å; Y44-D299 VanDerWaalsContact OH-CG 3.26Å; Y44-D299 PolarHBondContact OH-OD1 3.34Å; Y44-D299 PolarHBondContact OH-OD2 3.44Å; Y44-R327 VanDerWaalsContact CD2-CZ 3.46Å; Y44-R327 VanDerWaalsContact CD2-NH1 3.32Å; Y44-R327 VanDerWaalsContact CE2-CZ 3.41Å
45E94.7Very high91.9Very high25 Ų2551.4 Ų51.412%0.11727%0.273CS..SBendtrans-60.3151.2175.8-68.9-168.9-164.600111.8G42 V322 Q346 R372G42-E45 PolarHBondContact N-OE1 3.08Å; G42-E45 WeakPolarHBondContact O-CG 3.32Å; G42-E45 PolarHBondContact O-N 3.31Å; E45-V322 HydrophobicContact CG-CB 4.07Å; E45-V322 HydrophobicContact CG-CG1 3.68Å; E45-Q346 VanDerWaalsContact CD-CG 3.47Å; E45-Q346 HydrophobicContact CG-CB 4.1Å; E45-Q346 HydrophobicContact CG-CG 3.77Å; E45-Q346 PolarHBondContact OE1-NE2 2.76Å; E45-R372 IonicContact OE1-CZ 2.99Å; E45-R372 IonicContact OE1-NH1 3.3Å; E45-R372 IonicContact OE1-NH2 3.66Å; E45-R372 PolarHBondContact OE1-NH2 2.78Å; E45-R372 IonicContact OE2-CZ 3.89Å; E45-R372 IonicContact OE2-NH1 2.69Å; E45-R372 PolarHBondContact OE2-NH1 3.26Å; E45-R372 IonicContact OE2-NH2 3.98Å; E45-R372 PolarHBondContact OE2-NH2 3.29Å; E45-R372 VanDerWaalsContact OE2-NH2 3.08Å
46A96.3Very high91.9Very high11 Ų1155.3 Ų55.39%0.09129%0.287CS..PPolyproline II helixtrans-59.3143.6164.900000110E48 K103 A108 Q346A46-E48 PolarHBondContact O-N 3.37Å; A46-K103 HydrophobicContact CB-CD 4.35Å; A46-A108 HydrophobicContact CB-CB 3.59Å; A46-Q346 WeakPolarHBondContact CB-O 3.42Å; A46-Q346 PolarHBondContact N-O 2.82Å
47L97Very high91.8Very high70 Ų7059.3 Ų59.337%0.36630%0.301SS..PPolyproline II helixtrans-71.2118.7-167.9-176.472.5000111.6L49 N102 G107 A108L47-L49 PolarHBondContact O-N 2.66Å; L47-N102 PolarHBondContact N-O 2.87Å; L47-G107 CarbonylContact O-C 3.54Å; L47-G107 WeakPolarHBondContact O-CA 3.23Å; L47-A108 WeakPolarHBondContact O-CB 3.49Å; L47-A108 PolarHBondContact O-N 2.97Å
48E97.4Very high91.9Very high43 Ų4367 Ų6720%0.20134%0.339CS..  trans-76109.8163.4-167.3-171.5146.100110.1S37 A46 R50 N109S37-E48 WeakPolarHBondContact CB-OE2 3.34Å; S37-E48 VanDerWaalsContact OG-CD 3.29Å; S37-E48 PolarHBondContact OG-OE1 3.02Å; S37-E48 VanDerWaalsContact OG-OE1 3.09Å; S37-E48 PolarHBondContact OG-OE2 2.85Å; A46-E48 PolarHBondContact O-N 3.37Å; E48-R50 PolarHBondContact O-N 3.07Å; E48-R50 IonicContact OE1-CZ 3.28Å; E48-R50 IonicContact OE1-NE 2.78Å; E48-R50 PolarHBondContact OE1-NE 3.4Å; E48-R50 IonicContact OE1-NH2 3Å; E48-R50 PolarHBondContact OE1-NH2 2.89Å; E48-N109 HydrophobicContact CG-CB 4.16Å
49L97.9Very high92.5Very high27 Ų2766.9 Ų66.914%0.14134%0.338CS..  trans-78.3114.7-176.4-177.165.3000111.1L47 K64 A65 F106 N109L47-L49 PolarHBondContact O-N 2.66Å; L49-K64 HydrophobicContact CD2-CB 4.01Å; L49-K64 HydrophobicContact CG-CB 4.42Å; L49-A65 HydrophobicContact CB-CB 4.42Å; L49-A65 HydrophobicContact CD2-CB 4.45Å; L49-F106 WeakPolarHBondContact CD2-O 3.46Å; L49-N109 PolarHBondContact N-OD1 3.17Å; L49-N109 PolarHBondContact O-ND2 3.18Å
50R98.1Very high93.5Very high33 Ų3369.1 Ų69.113%0.12534%0.34CS..  trans-109.5153.8173.3-63.2-67.8-172.3162.5-5.5111.3P18 S37 E48 N52 K60 G61P18-R50 PolarHBondContact O-NH1 2.96Å; S37-R50 PolarHBondContact OG-NH2 3.28Å; E48-R50 PolarHBondContact O-N 3.07Å; E48-R50 IonicContact OE1-CZ 3.28Å; E48-R50 IonicContact OE1-NE 2.78Å; E48-R50 PolarHBondContact OE1-NE 3.4Å; E48-R50 IonicContact OE1-NH2 3Å; E48-R50 PolarHBondContact OE1-NH2 2.89Å; R50-N52 VanDerWaalsContact C-N 3.34Å; R50-N52 PolarHBondContact O-N 3.37Å; R50-N52 PolarHBondContact O-ND2 3.46Å; R50-K60 PolarHBondContact NH1-O 3.06Å; R50-G61 CarbonylContact C-O 3.52Å; R50-G61 WeakPolarHBondContact CA-O 3.4Å
51D97.8Very high95Very high11 Ų1168.9 Ų68.96%0.05934%0.339CS..  trans-68.6-33.6-177.2-68.1-18.6000112.5D53 R56 G61 V62 S63 K64D51-D53 PolarHBondContact O-N 3.4Å; D51-R56 IonicContact OD2-NH1 2.76Å; D51-G61 VanDerWaalsContact CG-O 3.24Å; D51-G61 PolarHBondContact N-O 3.04Å; D51-G61 WeakPolarHBondContact OD2-CA 3.36Å; D51-V62 PolarHBondContact OD2-N 2.92Å; D51-S63 PolarHBondContact OD1-N 3.17Å; D51-S63 PolarHBondContact OD1-OG 2.85Å; D51-S63 VanDerWaalsContact OD1-OG 3.1Å; D51-S63 WeakPolarHBondContact OD2-CB 3.43Å; D51-S63 PolarHBondContact OD2-N 3.45Å; D51-S63 PolarHBondContact OD2-OG 2.85Å; D51-K64 PolarHBondContact O-NZ 3.19Å; D51-K64 WeakPolarHBondContact OD1-CG 3.39Å; D51-K64 PolarHBondContact OD1-N 3.29Å
52N96.9Very high95.9Very high127 Ų12765.5 Ų65.568%0.67932%0.318SS*.  trans59.720.1-175.1-64.8-50.6000114.5R50 K54 G59R50-N52 VanDerWaalsContact C-N 3.34Å; R50-N52 PolarHBondContact O-N 3.37Å; R50-N52 PolarHBondContact O-ND2 3.46Å; N52-K54 PolarHBondContact O-N 2.78Å; N52-G59 VanDerWaalsContact CA-O 3.27Å; N52-G59 WeakPolarHBondContact CA-O 3.43Å; N52-G59 PolarHBondContact N-O 3.36Å
53D97.2Very high96.8Very high71 Ų7167.9 Ų67.938%0.3833%0.334SS..  trans-82.6103.1170.6177.82.5000110.5D51 T55 R56 G59D51-D53 PolarHBondContact O-N 3.4Å; D53-T55 VanDerWaalsContact CG-OG1 3.27Å; D53-T55 PolarHBondContact O-N 2.95Å; D53-T55 WeakPolarHBondContact OD1-CB 3.45Å; D53-T55 PolarHBondContact OD1-N 3.34Å; D53-T55 PolarHBondContact OD1-OG1 2.96Å; D53-T55 PolarHBondContact OD2-OG1 3.19Å; D53-R56 HydrophobicContact CB-CB 4.45Å; D53-R56 PolarHBondContact O-N 3.09Å; D53-G59 WeakPolarHBondContact O-CA 3.47Å; D53-G59 PolarHBondContact O-N 3.4Å; D53-G59 VanDerWaalsContact O-N 3.07Å
54K96.3Very high97.3Very high185 Ų18567 Ų6780%0.80433%0.326SS*.THydrogen-bonded Turntrans-58.8-20.8-178.5-66.7-174.7178.8-179.10113.6N52 R56N52-K54 PolarHBondContact O-N 2.78Å; K54-R56 VanDerWaalsContact C-N 3.31Å
55T97.6Very high97.5Very high128 Ų12862.8 Ų62.879%0.78531%0.309SS*.THydrogen-bonded Turntrans-80.5-13.717973.30000113.1D53D53-T55 VanDerWaalsContact CG-OG1 3.27Å; D53-T55 PolarHBondContact O-N 2.95Å; D53-T55 WeakPolarHBondContact OD1-CB 3.45Å; D53-T55 PolarHBondContact OD1-N 3.34Å; D53-T55 PolarHBondContact OD1-OG1 2.96Å; D53-T55 PolarHBondContact OD2-OG1 3.19Å
56R97.7Very high97.7Very high83 Ų8362.5 Ų62.531%0.31331%0.309SS..SBendtrans-124.9117.8-177.4-172.6-177.6-172.3-90.4-3.9111.1E10 D51 D53 K54 M58 G59E10-R56 IonicContact OE1-CZ 3.73Å; E10-R56 VanDerWaalsContact OE1-CZ 3.3Å; E10-R56 IonicContact OE1-NH1 3.11Å; E10-R56 PolarHBondContact OE1-NH1 3.08Å; E10-R56 VanDerWaalsContact OE1-NH1 3.16Å; E10-R56 IonicContact OE1-NH2 2.84Å; E10-R56 PolarHBondContact OE1-NH2 2.97Å; E10-R56 IonicContact OE2-CZ 3.56Å; E10-R56 IonicContact OE2-NH1 2.61Å; E10-R56 PolarHBondContact OE2-NH1 3.05Å; E10-R56 IonicContact OE2-NH2 2.87Å; D51-R56 IonicContact OD2-NH1 2.76Å; D53-R56 HydrophobicContact CB-CB 4.45Å; D53-R56 PolarHBondContact O-N 3.09Å; K54-R56 VanDerWaalsContact C-N 3.31Å; R56-M58 PolarHBondContact O-N 3.02Å; R56-M58 VanDerWaalsContact O-N 3.1Å; R56-G59 PolarHBondContact O-N 2.93Å
57Y97.4Very high97.8Very high96 Ų9666.2 Ų66.238%0.37633%0.325SS..G310 helixtrans48.638.2179.3-56.5-62.1000113.7E10 F12 P18 G59 K60E10-Y57 WeakPolarHBondContact OE1-CE2 3.26Å; F12-Y57 HydrophobicContact CE1-CD1 4.19Å; F12-Y57 AromaticContact CE1-CE1 3.67Å; F12-Y57 HydrophobicContact CE1-CE1 3.67Å; F12-Y57 AromaticContact CZ-CE1 3.67Å; F12-Y57 HydrophobicContact CZ-CE1 3.67Å; F12-Y57 AromaticContact CZ-CZ 3.78Å; F12-Y57 WeakPolarHBondContact CZ-OH 3.48Å; P18-Y57 HydrophobicContact CB-CD2 4.44Å; P18-Y57 HydrophobicContact CG-CD1 4.03Å; P18-Y57 HydrophobicContact CG-CD2 3.31Å; P18-Y57 HydrophobicContact CG-CE1 4.5Å; P18-Y57 HydrophobicContact CG-CE2 3.82Å; P18-Y57 HydrophobicContact CG-CG 3.42Å; P18-Y57 VanDerWaalsContact CG-CG 3.42Å; Y57-G59 PolarHBondContact O-N 3.42Å; Y57-K60 VanDerWaalsContact O-CB 3.3Å; Y57-K60 WeakPolarHBondContact O-CB 3.36Å; Y57-K60 PolarHBondContact O-N 3.19Å
58M96.8Very high97.9Very high165 Ų16565.3 Ų65.381%0.81332%0.319SS*.G310 helixtrans57.531-179.5-44.3-58.6174.100113.7R56 K60R56-M58 PolarHBondContact O-N 3.02Å; R56-M58 VanDerWaalsContact O-N 3.1Å; M58-K60 VanDerWaalsContact C-N 3.35Å
59G97.2Very high98Very high7 Ų763.3 Ų63.37%0.07231%0.309CS..G310 helixtrans89.3-6.4-175.700000114.9N52 D53 R56 Y57 G61N52-G59 VanDerWaalsContact CA-O 3.27Å; N52-G59 WeakPolarHBondContact CA-O 3.43Å; N52-G59 PolarHBondContact N-O 3.36Å; D53-G59 WeakPolarHBondContact O-CA 3.47Å; D53-G59 PolarHBondContact O-N 3.4Å; D53-G59 VanDerWaalsContact O-N 3.07Å; R56-G59 PolarHBondContact O-N 2.93Å; Y57-G59 PolarHBondContact O-N 3.42Å; G59-G61 PolarHBondContact O-N 3.2Å
60K98.1Very high98Very high85 Ų8564.3 Ų64.337%0.3731%0.314SS..THydrogen-bonded Turntrans-93.714.2-171.3-55.6-179.7-175.6179.40114.3N17 R50 Y57 M58N17-K60 HydrophobicContact CB-CD 4.3Å; N17-K60 WeakPolarHBondContact OD1-CD 3.3Å; N17-K60 PolarHBondContact OD1-NZ 3.06Å; R50-K60 PolarHBondContact NH1-O 3.06Å; Y57-K60 VanDerWaalsContact O-CB 3.3Å; Y57-K60 WeakPolarHBondContact O-CB 3.36Å; Y57-K60 PolarHBondContact O-N 3.19Å; M58-K60 VanDerWaalsContact C-N 3.35Å
61G98.4Very high98.1Very high0 Ų069.4 Ų69.40%034%0.338CS..  trans-57155.8171.400000112.5R50 D51 G59R50-G61 CarbonylContact C-O 3.52Å; R50-G61 WeakPolarHBondContact CA-O 3.4Å; D51-G61 VanDerWaalsContact CG-O 3.24Å; D51-G61 PolarHBondContact N-O 3.04Å; D51-G61 WeakPolarHBondContact OD2-CA 3.36Å; G59-G61 PolarHBondContact O-N 3.2Å
62V98.8Very high98.1Very high0 Ų071.7 Ų71.70%035%0.352CS..  trans-123.623.5175.3-650000112.2E10 P18 V20 D51 K64 A65 V66E10-V62 HydrophobicContact CB-CG2 4.12Å; E10-V62 HydrophobicContact CG-CG2 3.59Å; E10-V62 WeakPolarHBondContact OE2-CG2 3.31Å; E10-V62 PolarHBondContact OE2-N 3.06Å; P18-V62 HydrophobicContact CB-CG2 4.2Å; V20-V62 HydrophobicContact CG2-CB 4.06Å; V20-V62 HydrophobicContact CG2-CG2 4.05Å; D51-V62 PolarHBondContact OD2-N 2.92Å; V62-K64 VanDerWaalsContact C-N 3.27Å; V62-K64 PolarHBondContact O-N 3Å; V62-A65 HydrophobicContact CB-CB 4.49Å; V62-A65 PolarHBondContact O-N 3.45Å; V62-V66 HydrophobicContact CG2-CG2 4.33Å; V62-V66 WeakPolarHBondContact O-CG2 3.4Å; V62-V66 PolarHBondContact O-N 3.18Å
63S98.6Very high98.2Very high54 Ų5465.7 Ų65.738%0.37832%0.32SS..Hα-helixtrans-60.5-35.4-17764.50000112.6D51 V66 E67D51-S63 PolarHBondContact OD1-N 3.17Å; D51-S63 PolarHBondContact OD1-OG 2.85Å; D51-S63 VanDerWaalsContact OD1-OG 3.1Å; D51-S63 WeakPolarHBondContact OD2-CB 3.43Å; D51-S63 PolarHBondContact OD2-N 3.45Å; D51-S63 PolarHBondContact OD2-OG 2.85Å; S63-V66 PolarHBondContact O-N 3.41Å; S63-E67 VanDerWaalsContact O-CB 3.31Å; S63-E67 WeakPolarHBondContact O-CB 3.44Å; S63-E67 PolarHBondContact O-N 3.08Å
64K98.7Very high98.2Very high97 Ų9762.6 Ų62.642%0.42231%0.305SS..Hα-helixtrans-62.5-46.9173.8-68175-176.8166.20112.7L49 D51 V62 E67 H68L49-K64 HydrophobicContact CD2-CB 4.01Å; L49-K64 HydrophobicContact CG-CB 4.42Å; D51-K64 PolarHBondContact O-NZ 3.19Å; D51-K64 WeakPolarHBondContact OD1-CG 3.39Å; D51-K64 PolarHBondContact OD1-N 3.29Å; V62-K64 VanDerWaalsContact C-N 3.27Å; V62-K64 PolarHBondContact O-N 3Å; K64-E67 WeakPolarHBondContact O-CB 3.16Å; K64-E67 PolarHBondContact O-N 2.91Å; K64-H68 PolarHBondContact O-CD2 2.9Å; K64-H68 PolarHBondContact O-N 2.95Å
65A98.8Very high98.3Very high0 Ų057 Ų570%029%0.287CS..Hα-helixtrans-62.5-44.9177.200000111.3V20 L49 V62 E67 H68 I69 A110V20-A65 HydrophobicContact CG2-CB 3.91Å; L49-A65 HydrophobicContact CB-CB 4.42Å; L49-A65 HydrophobicContact CD2-CB 4.45Å; V62-A65 HydrophobicContact CB-CB 4.49Å; V62-A65 PolarHBondContact O-N 3.45Å; A65-E67 VanDerWaalsContact C-N 3.29Å; A65-E67 PolarHBondContact O-N 3.07Å; A65-H68 PolarHBondContact O-N 3.1Å; A65-I69 WeakPolarHBondContact O-CG1 3.26Å; A65-I69 PolarHBondContact O-N 3.44Å; A65-I69 VanDerWaalsContact O-N 3.12Å; A65-A110 HydrophobicContact CB-CB 4.28Å
66V98.9Very high98.4Very high19 Ų1951.9 Ų51.912%0.11526%0.257CS..Hα-helixtrans-59.3-40.3174.3169.80000111.4A8 E10 V20 V62 S63 I69 N70A8-V66 HydrophobicContact CB-CG1 4.13Å; A8-V66 WeakPolarHBondContact O-CG1 3.33Å; E10-V66 HydrophobicContact CB-CG2 4.47Å; V20-V66 HydrophobicContact CG2-CG2 4.3Å; V62-V66 HydrophobicContact CG2-CG2 4.33Å; V62-V66 WeakPolarHBondContact O-CG2 3.4Å; V62-V66 PolarHBondContact O-N 3.18Å; S63-V66 PolarHBondContact O-N 3.41Å; V66-I69 PolarHBondContact O-N 3.26Å; V66-N70 WeakPolarHBondContact CG1-ND2 3.44Å; V66-N70 WeakPolarHBondContact O-CB 2.82Å; V66-N70 PolarHBondContact O-N 3.5Å; V66-N70 PolarHBondContact O-ND2 3.36Å; V66-N70 VanDerWaalsContact O-ND2 3.13Å
67E98.8Very high98.3Very high90 Ų9048 Ų4842%0.42124%0.243SC..Hα-helixtrans-65.3-44.9176.8-175.5172.3-176.500112.1S63 K64 A65 I69 N70 K71S63-E67 VanDerWaalsContact O-CB 3.31Å; S63-E67 WeakPolarHBondContact O-CB 3.44Å; S63-E67 PolarHBondContact O-N 3.08Å; K64-E67 WeakPolarHBondContact O-CB 3.16Å; K64-E67 PolarHBondContact O-N 2.91Å; A65-E67 VanDerWaalsContact C-N 3.29Å; A65-E67 PolarHBondContact O-N 3.07Å; E67-I69 VanDerWaalsContact C-N 3.27Å; E67-I69 PolarHBondContact O-N 2.79Å; E67-N70 PolarHBondContact O-N 3.14Å; E67-K71 HydrophobicContact CG-CD 3.63Å; E67-K71 HydrophobicContact CG-CG 4.04Å; E67-K71 WeakPolarHBondContact O-CB 3.33Å; E67-K71 PolarHBondContact O-N 3.3Å; E67-K71 WeakPolarHBondContact OE1-CD 3.41Å; E67-K71 WeakPolarHBondContact OE1-CE 3.35Å; E67-K71 IonicContact OE1-NZ 3.63Å; E67-K71 PolarHBondContact OE1-NZ 3.01Å
68H98.9Very high98.3Very high51 Ų5145.8 Ų45.824%0.23624%0.239CC..Hα-helixtrans-57.1-41.3175.1-72.3-52.3000112K64 A65 T72 I73 K105 F106K64-H68 PolarHBondContact O-CD2 2.9Å; K64-H68 PolarHBondContact O-N 2.95Å; A65-H68 PolarHBondContact O-N 3.1Å; H68-T72 WeakPolarHBondContact O-CA 3.1Å; H68-T72 VanDerWaalsContact O-CB 3.27Å; H68-T72 WeakPolarHBondContact O-CB 3.38Å; H68-T72 PolarHBondContact O-N 3.43Å; H68-I73 PolarHBondContact O-N 3.24Å; H68-K105 PolarHBondContact NE2-O 2.82Å; H68-F106 HydrophobicContact CB-CB 4.33Å; H68-F106 HydrophobicContact CB-CD1 4.08Å; H68-F106 HydrophobicContact CB-CG 4.44Å; H68-F106 AromaticContact CG-CD1 3.89Å; H68-F106 AromaticContact ND1-CD1 3.82Å
69I98.9Very high98.3Very high0 Ų041.8 Ų41.80%023%0.228CC..Iπ-helixtrans-64-55.1176-59.2162.2000110.2V6 A8 V20 V22 A65 V66 E67 K71 I73 A74 A110 V114V6-I69 HydrophobicContact CG1-CG2 3.93Å; A8-I69 HydrophobicContact CB-CB 3.68Å; A8-I69 HydrophobicContact CB-CD1 3.45Å; A8-I69 VanDerWaalsContact CB-CD1 3.45Å; A8-I69 HydrophobicContact CB-CG1 4.2Å; A8-I69 HydrophobicContact CB-CG2 3.67Å; V20-I69 HydrophobicContact CG1-CD1 3.5Å; V22-I69 HydrophobicContact CG2-CD1 3.77Å; A65-I69 WeakPolarHBondContact O-CG1 3.26Å; A65-I69 PolarHBondContact O-N 3.44Å; A65-I69 VanDerWaalsContact O-N 3.12Å; V66-I69 PolarHBondContact O-N 3.26Å; E67-I69 VanDerWaalsContact C-N 3.27Å; E67-I69 PolarHBondContact O-N 2.79Å; I69-K71 PolarHBondContact O-N 3.09Å; I69-I73 HydrophobicContact CG1-CD1 4.26Å; I69-I73 PolarHBondContact O-N 2.88Å; I69-A74 WeakPolarHBondContact O-CB 3.36Å; I69-A74 PolarHBondContact O-N 3.35Å; I69-A110 HydrophobicContact CD1-CB 4.18Å; I69-A110 HydrophobicContact CG1-CB 3.8Å; I69-V114 HydrophobicContact CG1-CG2 4.26Å; I69-V114 HydrophobicContact CG2-CG2 3.73Å
70N98.9Very high98.2Very high48 Ų4847.7 Ų47.726%0.25725%0.251SS..Iπ-helixtrans-67.4-38.1-171.9-77-43.5000113.3H7 A8 V66 E67H7-N70 WeakPolarHBondContact CA-OD1 3.28Å; H7-N70 PolarHBondContact ND1-OD1 2.7Å; H7-N70 VanDerWaalsContact ND1-OD1 3.12Å; A8-N70 PolarHBondContact N-OD1 3.33Å; A8-N70 PolarHBondContact O-ND2 3.4Å; V66-N70 WeakPolarHBondContact CG1-ND2 3.44Å; V66-N70 WeakPolarHBondContact O-CB 2.82Å; V66-N70 PolarHBondContact O-N 3.5Å; V66-N70 PolarHBondContact O-ND2 3.36Å; V66-N70 VanDerWaalsContact O-ND2 3.13Å; E67-N70 PolarHBondContact O-N 3.14Å
71K98.7Very high98Very high141 Ų14151.2 Ų51.261%0.61327%0.267SS*.Iπ-helixtrans-99.3-18.5-172.7-62.2-169.1-174.7171.60114.2E67 I69E67-K71 HydrophobicContact CG-CD 3.63Å; E67-K71 HydrophobicContact CG-CG 4.04Å; E67-K71 WeakPolarHBondContact O-CB 3.33Å; E67-K71 PolarHBondContact O-N 3.3Å; E67-K71 WeakPolarHBondContact OE1-CD 3.41Å; E67-K71 WeakPolarHBondContact OE1-CE 3.35Å; E67-K71 IonicContact OE1-NZ 3.63Å; E67-K71 PolarHBondContact OE1-NZ 3.01Å; I69-K71 PolarHBondContact O-N 3.09Å
72T98.6Very high97.8Very high59 Ų5952.9 Ų52.936%0.36228%0.276SS..Iπ-helixtrans-124.2-57.6-174.4-49.80000112.6H68 A76 M97 F106H68-T72 WeakPolarHBondContact O-CA 3.1Å; H68-T72 VanDerWaalsContact O-CB 3.27Å; H68-T72 WeakPolarHBondContact O-CB 3.38Å; H68-T72 PolarHBondContact O-N 3.43Å; T72-A76 WeakPolarHBondContact O-CB 3.27Å; T72-A76 PolarHBondContact O-N 2.93Å; T72-M97 HydrophobicContact CG2-CE 4.12Å; T72-F106 HydrophobicContact CG2-CE1 4.03Å; T72-F106 HydrophobicContact CG2-CZ 3.88Å
73I98.7Very high97.7Very high0 Ų055.1 Ų55.10%029%0.287CS..Iπ-helixtrans-69.2-46.6-175.9-59.6171.6000110.6H68 I69 A76 L77 M94 F106 A110 V114H68-I73 PolarHBondContact O-N 3.24Å; I69-I73 HydrophobicContact CG1-CD1 4.26Å; I69-I73 PolarHBondContact O-N 2.88Å; I73-A76 PolarHBondContact O-N 3.42Å; I73-L77 HydrophobicContact CG2-CD1 3.75Å; I73-L77 HydrophobicContact CG2-CG 4.04Å; I73-L77 WeakPolarHBondContact O-CG 3.48Å; I73-L77 PolarHBondContact O-N 2.98Å; I73-M94 HydrophobicContact CG2-CG 4.06Å; I73-M94 HydrophobicContact CG2-SD 3.84Å; I73-F106 HydrophobicContact CD1-CD2 4.03Å; I73-F106 HydrophobicContact CD1-CG 4.41Å; I73-F106 HydrophobicContact CG1-CD2 4.19Å; I73-F106 HydrophobicContact CG1-CE2 4.22Å; I73-A110 HydrophobicContact CD1-CB 4.34Å; I73-V114 HydrophobicContact CG2-CG1 4.38Å; I73-V114 HydrophobicContact CG2-CG2 4.19Å
74A98.6Very high97.6Very high7 Ų752.6 Ų52.66%0.05827%0.27CS..Hα-helixtrans-59.7-51.2-176.400000113V6 I69 A76 L77 V78V6-A74 HydrophobicContact CB-CB 3.66Å; V6-A74 HydrophobicContact CG1-CB 4.24Å; I69-A74 WeakPolarHBondContact O-CB 3.36Å; I69-A74 PolarHBondContact O-N 3.35Å; A74-A76 VanDerWaalsContact C-N 3.31Å; A74-A76 PolarHBondContact O-N 3.36Å; A74-L77 PolarHBondContact O-N 3.33Å; A74-V78 WeakPolarHBondContact O-CG2 3.34Å; A74-V78 PolarHBondContact O-N 3.45Å; A74-V78 VanDerWaalsContact O-N 3.1Å
75P98.3Very high97.6Very high68 Ų6849.7 Ų49.744%0.44226%0.26SS..Hα-helixtrans-60.6-38.6176.1-24.135000113S79P75-S79 VanDerWaalsContact O-CB 3.31Å; P75-S79 WeakPolarHBondContact O-CB 3.17Å; P75-S79 PolarHBondContact O-N 3.26Å; P75-S79 PolarHBondContact O-OG 3.49Å
76A97.9Very high97.5Very high19 Ų1952.4 Ų52.416%0.15727%0.273CS..Hα-helixtrans-63.6-49.2178.800000111.6T72 I73 A74 V78 S79 K80 M97T72-A76 WeakPolarHBondContact O-CB 3.27Å; T72-A76 PolarHBondContact O-N 2.93Å; I73-A76 PolarHBondContact O-N 3.42Å; A74-A76 VanDerWaalsContact C-N 3.31Å; A74-A76 PolarHBondContact O-N 3.36Å; A76-V78 PolarHBondContact O-N 2.61Å; A76-S79 PolarHBondContact O-N 3.09Å; A76-S79 PolarHBondContact O-OG 2.88Å; A76-K80 VanDerWaalsContact O-CG 3.26Å; A76-K80 WeakPolarHBondContact O-CG 3.43Å; A76-K80 PolarHBondContact O-N 3.39Å; A76-M97 HydrophobicContact CB-CE 3.46Å; A76-M97 VanDerWaalsContact CB-CE 3.46Å; A76-M97 HydrophobicContact CB-SD 3.64Å
77L97.2Very high97.5Very high1 Ų151.6 Ų51.61%0.00527%0.268CS..Hα-helixtrans-63.8-42.5-179.8-68.4-175.9000112.8I3 I73 A74 K80 K81 I90 L93 M94 V114I3-L77 HydrophobicContact CD1-CB 4.05Å; I3-L77 HydrophobicContact CD1-CD1 4.28Å; I73-L77 HydrophobicContact CG2-CD1 3.75Å; I73-L77 HydrophobicContact CG2-CG 4.04Å; I73-L77 WeakPolarHBondContact O-CG 3.48Å; I73-L77 PolarHBondContact O-N 2.98Å; A74-L77 PolarHBondContact O-N 3.33Å; L77-K80 PolarHBondContact O-N 3Å; L77-K81 PolarHBondContact O-N 3.2Å; L77-I90 HydrophobicContact CD1-CG2 4.37Å; L77-I90 HydrophobicContact CD2-CG2 3.94Å; L77-L93 HydrophobicContact CD2-CD2 3.77Å; L77-M94 HydrophobicContact CD1-SD 4.21Å; L77-M94 HydrophobicContact CD2-CG 4.4Å; L77-V114 HydrophobicContact CD1-CG1 3.44Å; L77-V114 VanDerWaalsContact CD1-CG1 3.44Å
78V97.3Very high97.5Very high50 Ų5053.3 Ų53.330%0.30328%0.276SS..Hα-helixtrans-63.4-42.2176.5173.60000110.8I3 A74 A76 K81I3-V78 HydrophobicContact CG2-CG2 4.17Å; A74-V78 WeakPolarHBondContact O-CG2 3.34Å; A74-V78 PolarHBondContact O-N 3.45Å; A74-V78 VanDerWaalsContact O-N 3.1Å; A76-V78 PolarHBondContact O-N 2.61Å; V78-K81 PolarHBondContact O-N 2.88Å
79S96.9Very high97.5Very high82 Ų8256.5 Ų56.557%0.57329%0.289SS*.Hα-helixtrans-68.3-34.7-179.470.70000113.6P75 A76 K81P75-S79 VanDerWaalsContact O-CB 3.31Å; P75-S79 WeakPolarHBondContact O-CB 3.17Å; P75-S79 PolarHBondContact O-N 3.26Å; P75-S79 PolarHBondContact O-OG 3.49Å; A76-S79 PolarHBondContact O-N 3.09Å; A76-S79 PolarHBondContact O-OG 2.88Å; S79-K81 VanDerWaalsContact C-N 3.29Å; S79-K81 PolarHBondContact O-N 3.14Å
80K94.9Very high97.5Very high131 Ų13156.5 Ų56.557%0.5729%0.289SS*.Hα-helixtrans-73.3-19.5-179.7-68.7-73.6-174.5-179.80113.5A76 L77 L82 L93A76-K80 VanDerWaalsContact O-CG 3.26Å; A76-K80 WeakPolarHBondContact O-CG 3.43Å; A76-K80 PolarHBondContact O-N 3.39Å; L77-K80 PolarHBondContact O-N 3Å; K80-L82 HydrophobicContact CB-CD1 4.45Å; K80-L82 HydrophobicContact CB-CG 4.05Å; K80-L82 PolarHBondContact O-N 3.42Å; K80-L82 VanDerWaalsContact O-N 3.14Å; K80-L93 HydrophobicContact CB-CD2 4.32Å; K80-L93 HydrophobicContact CG-CD2 3.83Å
81K93.1Very high97.5Very high158 Ų15854.2 Ų54.269%0.68728%0.277SS*.THydrogen-bonded Turntrans52.732178.8-58.6-178.7180-179.60113.8L77 V78 S79L77-K81 PolarHBondContact O-N 3.2Å; V78-K81 PolarHBondContact O-N 2.88Å; S79-K81 VanDerWaalsContact C-N 3.29Å; S79-K81 PolarHBondContact O-N 3.14Å
82L94.1Very high97.5Very high36 Ų3653.3 Ų53.319%0.18827%0.273CS..  trans-63148.3175.5-64.7175.8000110.6K80 I90 L93K80-L82 HydrophobicContact CB-CD1 4.45Å; K80-L82 HydrophobicContact CB-CG 4.05Å; K80-L82 PolarHBondContact O-N 3.42Å; K80-L82 VanDerWaalsContact O-N 3.14Å; L82-I90 HydrophobicContact CB-CD1 4.24Å; L82-I90 HydrophobicContact CB-CG1 3.86Å; L82-I90 HydrophobicContact CD1-CG1 3.75Å; L82-I90 HydrophobicContact CG-CG1 4.47Å; L82-L93 HydrophobicContact CD1-CD2 3.86Å
83N96.3Very high97.5Very high47 Ų4751.6 Ų51.625%0.25126%0.261SS..BIsolated β-bridgetrans-77.6132.8175.8-174.3-17.8000109.8M1 T85 E86 I90M1-N83 PolarHBondContact N-ND2 3.44Å; M1-N83 PolarHBondContact N-OD1 3.43Å; M1-N83 WeakPolarHBondContact O-CA 3.4Å; M1-N83 PolarHBondContact O-OD1 3.47Å; N83-T85 PolarHBondContact ND2-OG1 2.91Å; N83-T85 PolarHBondContact O-N 3.39Å; N83-T85 PolarHBondContact OD1-N 2.8Å; N83-T85 VanDerWaalsContact OD1-N 3.08Å; N83-T85 PolarHBondContact OD1-OG1 2.76Å; N83-E86 HydrophobicContact CB-CG 4.03Å; N83-E86 WeakPolarHBondContact CB-OE2 3.48Å; N83-E86 PolarHBondContact N-OE2 3.4Å; N83-E86 VanDerWaalsContact O-CB 3.31Å; N83-E86 WeakPolarHBondContact O-CB 3.27Å; N83-E86 PolarHBondContact O-N 2.71Å; N83-I90 WeakPolarHBondContact O-CD1 3.43Å
84V97.6Very high97.5Very high0 Ų051.6 Ų51.60%026%0.261CS..THydrogen-bonded Turntrans-58.1-18.4177.1-66.30000114.1M1 I3 L24 T26 E86 A121 E125M1-V84 PolarHBondContact O-N 3.03Å; M1-V84 VanDerWaalsContact O-N 3.09Å; I3-V84 HydrophobicContact CD1-CG1 4.37Å; I3-V84 HydrophobicContact CG1-CG1 3.61Å; L24-V84 HydrophobicContact CD2-CG1 4.17Å; T26-V84 HydrophobicContact CG2-CG1 3.9Å; V84-E86 VanDerWaalsContact C-N 3.26Å; V84-E86 PolarHBondContact O-N 2.81Å; V84-A121 HydrophobicContact CB-CB 3.98Å; V84-A121 HydrophobicContact CG1-CB 4Å; V84-A121 HydrophobicContact CG2-CB 4.12Å; V84-E125 HydrophobicContact CG2-CB 3.86Å; V84-E125 HydrophobicContact CG2-CG 4.15Å
85T98Very high97.5Very high36 Ų3653.4 Ų53.422%0.22127%0.27CS..THydrogen-bonded Turntrans-76.6-10.5172.262.40000113.8N83 Q87 E125 K126N83-T85 PolarHBondContact ND2-OG1 2.91Å; N83-T85 PolarHBondContact O-N 3.39Å; N83-T85 PolarHBondContact OD1-N 2.8Å; N83-T85 VanDerWaalsContact OD1-N 3.08Å; N83-T85 PolarHBondContact OD1-OG1 2.76Å; T85-Q87 VanDerWaalsContact C-N 3.32Å; T85-Q87 PolarHBondContact O-N 3.06Å; T85-E125 HydrophobicContact CG2-CB 4.01Å; T85-E125 HydrophobicContact CG2-CG 3.64Å; T85-K126 HydrophobicContact CG2-CG 3.91Å
86E98.1Very high97.5Very high58 Ų5856 Ų5627%0.27128%0.276SS..  trans-93.656-179.5-59.7177.7109.500110.9N83 V84 E88 K89 I90N83-E86 HydrophobicContact CB-CG 4.03Å; N83-E86 WeakPolarHBondContact CB-OE2 3.48Å; N83-E86 PolarHBondContact N-OE2 3.4Å; N83-E86 VanDerWaalsContact O-CB 3.31Å; N83-E86 WeakPolarHBondContact O-CB 3.27Å; N83-E86 PolarHBondContact O-N 2.71Å; V84-E86 VanDerWaalsContact C-N 3.26Å; V84-E86 PolarHBondContact O-N 2.81Å; E86-E88 VanDerWaalsContact C-N 3.28Å; E86-E88 PolarHBondContact O-N 3.47Å; E86-K89 HydrophobicContact CB-CB 4.1Å; E86-K89 HydrophobicContact CB-CD 4.15Å; E86-K89 HydrophobicContact CB-CG 4.26Å; E86-K89 HydrophobicContact CG-CD 4.4Å; E86-K89 PolarHBondContact O-N 3.12Å; E86-K89 WeakPolarHBondContact OE1-CD 3.26Å; E86-K89 WeakPolarHBondContact OE1-CE 3.2Å; E86-K89 IonicContact OE1-NZ 2.99Å; E86-K89 PolarHBondContact OE1-NZ 3.33Å; E86-I90 PolarHBondContact O-N 3.12Å; E86-I90 VanDerWaalsContact O-N 3.09Å
87Q98.8Very high97.5Very high2 Ų257.1 Ų57.11%0.00928%0.278CS..Hα-helixtrans-46.2-50.4-176.5-174.26946.700112.4T85 K89 I90 D91 S115 C119 L137 V350T85-Q87 VanDerWaalsContact C-N 3.32Å; T85-Q87 PolarHBondContact O-N 3.06Å; Q87-K89 PolarHBondContact O-N 3.13Å; Q87-I90 PolarHBondContact O-N 3.1Å; Q87-D91 PolarHBondContact NE2-OD1 3Å; Q87-D91 PolarHBondContact NE2-OD2 2.8Å; Q87-D91 WeakPolarHBondContact O-CB 3.31Å; Q87-D91 PolarHBondContact O-N 3.42Å; Q87-S115 PolarHBondContact NE2-O 3.46Å; Q87-S115 PolarHBondContact NE2-OG 2.75Å; Q87-S115 VanDerWaalsContact NE2-OG 3.17Å; Q87-C119 VanDerWaalsContact OE1-N 3.17Å; Q87-L137 HydrophobicContact CB-CD1 3.98Å; Q87-L137 HydrophobicContact CB-CD2 4.02Å; Q87-L137 HydrophobicContact CG-CD1 4.13Å; Q87-V350 HydrophobicContact CG-CB 4.35Å; Q87-V350 HydrophobicContact CG-CG1 4.26Å
88E98.6Very high97.6Very high125 Ų12557.3 Ų57.358%0.58428%0.279SS*.Hα-helixtrans-60.4-41.4-179.2-179.2178.4-177.700112.6E86 K92 T351E86-E88 VanDerWaalsContact C-N 3.28Å; E86-E88 PolarHBondContact O-N 3.47Å; E88-K92 WeakPolarHBondContact O-CB 3.46Å; E88-K92 PolarHBondContact O-N 3.5Å; E88-T351 WeakPolarHBondContact CA-OG1 3.38Å; E88-T351 HydrophobicContact CB-CG2 4.23Å; E88-T351 HydrophobicContact CG-CG2 4.07Å
89K98.4Very high97.7Very high118 Ų11858 Ų5851%0.51330%0.296SS..Hα-helixtrans-68.9-38.5179.9-65.3-173.3-174.5171.60111.6E86 Q87 L93E86-K89 HydrophobicContact CB-CB 4.1Å; E86-K89 HydrophobicContact CB-CD 4.15Å; E86-K89 HydrophobicContact CB-CG 4.26Å; E86-K89 HydrophobicContact CG-CD 4.4Å; E86-K89 PolarHBondContact O-N 3.12Å; E86-K89 WeakPolarHBondContact OE1-CD 3.26Å; E86-K89 WeakPolarHBondContact OE1-CE 3.2Å; E86-K89 IonicContact OE1-NZ 2.99Å; E86-K89 PolarHBondContact OE1-NZ 3.33Å; Q87-K89 PolarHBondContact O-N 3.13Å; K89-L93 WeakPolarHBondContact O-CB 3.32Å; K89-L93 PolarHBondContact O-N 3.49Å
90I98.7Very high97.7Very high0 Ų056.2 Ų56.20%028%0.282CS..Hα-helixtrans-70.7-46.8179.5-67.9166.6000110.5I3 L77 L82 N83 E86 Q87 L93 M94 V118I3-I90 HydrophobicContact CD1-CD1 4.29Å; L77-I90 HydrophobicContact CD1-CG2 4.37Å; L77-I90 HydrophobicContact CD2-CG2 3.94Å; L82-I90 HydrophobicContact CB-CD1 4.24Å; L82-I90 HydrophobicContact CB-CG1 3.86Å; L82-I90 HydrophobicContact CD1-CG1 3.75Å; L82-I90 HydrophobicContact CG-CG1 4.47Å; N83-I90 WeakPolarHBondContact O-CD1 3.43Å; E86-I90 PolarHBondContact O-N 3.12Å; E86-I90 VanDerWaalsContact O-N 3.09Å; Q87-I90 PolarHBondContact O-N 3.1Å; I90-L93 PolarHBondContact O-N 3.16Å; I90-M94 HydrophobicContact CG2-CE 4.11Å; I90-M94 WeakPolarHBondContact O-CG 3.49Å; I90-M94 PolarHBondContact O-N 2.91Å; I90-M94 VanDerWaalsContact O-N 3.09Å; I90-V118 HydrophobicContact CB-CG1 4.38Å; I90-V118 HydrophobicContact CD1-CG1 3.53Å; I90-V118 HydrophobicContact CD1-CG2 4.38Å; I90-V118 HydrophobicContact CG2-CG1 4.26Å; I90-V118 HydrophobicContact CG2-CG2 3.9Å
91D98.8Very high97.7Very high0 Ų057 Ų570%029%0.287CS..Hα-helixtrans-61-46.7176.5-73.5-20.4000111.1Q87 L93 M94 I95 S115 T351Q87-D91 PolarHBondContact NE2-OD1 3Å; Q87-D91 PolarHBondContact NE2-OD2 2.8Å; Q87-D91 WeakPolarHBondContact O-CB 3.31Å; Q87-D91 PolarHBondContact O-N 3.42Å; D91-L93 VanDerWaalsContact C-N 3.33Å; D91-L93 PolarHBondContact O-N 3.16Å; D91-M94 PolarHBondContact O-N 3.02Å; D91-M94 VanDerWaalsContact O-N 3.14Å; D91-M94 WeakPolarHBondContact OD1-CE 3.42Å; D91-I95 WeakPolarHBondContact O-CD1 3.43Å; D91-I95 VanDerWaalsContact O-CG1 3.25Å; D91-I95 WeakPolarHBondContact O-CG1 3.22Å; D91-I95 PolarHBondContact O-N 3.44Å; D91-S115 WeakPolarHBondContact OD1-CB 3.36Å; D91-S115 PolarHBondContact OD1-OG 3.31Å; D91-S115 PolarHBondContact OD2-OG 3.01Å; D91-T351 WeakPolarHBondContact OD2-CB 3.48Å; D91-T351 PolarHBondContact OD2-N 2.82Å; D91-T351 PolarHBondContact OD2-OG1 3.3Å
92K98.6Very high97.8Very high122 Ų12252.7 Ų52.753%0.5327%0.272SS..Hα-helixtrans-57.3-44.4176.7-180171.71761730112.2E88 M94 I95 E96E88-K92 WeakPolarHBondContact O-CB 3.46Å; E88-K92 PolarHBondContact O-N 3.5Å; K92-M94 PolarHBondContact O-N 3.4Å; K92-I95 PolarHBondContact O-N 2.89Å; K92-E96 WeakPolarHBondContact CE-OE1 3.49Å; K92-E96 HydrophobicContact CG-CG 4.35Å; K92-E96 WeakPolarHBondContact CG-OE1 3.4Å; K92-E96 IonicContact NZ-OE1 3.84Å; K92-E96 WeakPolarHBondContact O-CB 3.34Å; K92-E96 VanDerWaalsContact O-CG 3.29Å; K92-E96 WeakPolarHBondContact O-CG 3.41Å; K92-E96 PolarHBondContact O-N 2.98Å
93L98.6Very high98Very high23 Ų2351.1 Ų51.112%0.1226%0.264CS..Hα-helixtrans-59.8-45.3176.3172.963.3000111.8L77 K80 L82 K89 I90 D91 E96 M97L77-L93 HydrophobicContact CD2-CD2 3.77Å; K80-L93 HydrophobicContact CB-CD2 4.32Å; K80-L93 HydrophobicContact CG-CD2 3.83Å; L82-L93 HydrophobicContact CD1-CD2 3.86Å; K89-L93 WeakPolarHBondContact O-CB 3.32Å; K89-L93 PolarHBondContact O-N 3.49Å; I90-L93 PolarHBondContact O-N 3.16Å; D91-L93 VanDerWaalsContact C-N 3.33Å; D91-L93 PolarHBondContact O-N 3.16Å; L93-E96 PolarHBondContact O-N 3.48Å; L93-M97 HydrophobicContact CD1-CG 4.1Å; L93-M97 HydrophobicContact CD1-SD 3.96Å; L93-M97 HydrophobicContact CG-SD 3.96Å; L93-M97 WeakPolarHBondContact O-CB 3.41Å; L93-M97 WeakPolarHBondContact O-CG 3.28Å; L93-M97 PolarHBondContact O-N 3.22Å
94M98.8Very high98.1Very high0 Ų051 Ų510%027%0.267CS..Hα-helixtrans-65.2-40.3179.1-66.9-173.1-65.100112.1I73 L77 I90 D91 K92 M97 D98 I111 V114I73-M94 HydrophobicContact CG2-CG 4.06Å; I73-M94 HydrophobicContact CG2-SD 3.84Å; L77-M94 HydrophobicContact CD1-SD 4.21Å; L77-M94 HydrophobicContact CD2-CG 4.4Å; I90-M94 HydrophobicContact CG2-CE 4.11Å; I90-M94 WeakPolarHBondContact O-CG 3.49Å; I90-M94 PolarHBondContact O-N 2.91Å; I90-M94 VanDerWaalsContact O-N 3.09Å; D91-M94 PolarHBondContact O-N 3.02Å; D91-M94 VanDerWaalsContact O-N 3.14Å; D91-M94 WeakPolarHBondContact OD1-CE 3.42Å; K92-M94 PolarHBondContact O-N 3.4Å; M94-M97 PolarHBondContact O-N 2.81Å; M94-D98 PolarHBondContact O-N 3.38Å; M94-I111 HydrophobicContact CB-CG1 4.49Å; M94-I111 HydrophobicContact CB-CG2 3.99Å; M94-I111 HydrophobicContact CE-CG2 4.01Å; M94-I111 HydrophobicContact SD-CG2 4.4Å; M94-V114 HydrophobicContact CE-CB 4.36Å; M94-V114 HydrophobicContact CE-CG1 4.31Å; M94-V114 HydrophobicContact SD-CB 3.71Å; M94-V114 HydrophobicContact SD-CG1 3.58Å; M94-V114 VanDerWaalsContact SD-CG1 3.58Å; M94-V114 HydrophobicContact SD-CG2 4.49Å
95I98.7Very high98.1Very high46 Ų4656.4 Ų56.424%0.23629%0.29CS..Hα-helixtrans-64.1-44.6176.4-66.8161.9000110.8D91 K92 M97 D98 G99 E352D91-I95 WeakPolarHBondContact O-CD1 3.43Å; D91-I95 VanDerWaalsContact O-CG1 3.25Å; D91-I95 WeakPolarHBondContact O-CG1 3.22Å; D91-I95 PolarHBondContact O-N 3.44Å; K92-I95 PolarHBondContact O-N 2.89Å; I95-M97 VanDerWaalsContact C-N 3.35Å; I95-M97 PolarHBondContact O-N 3.48Å; I95-D98 PolarHBondContact O-N 3.17Å; I95-G99 PolarHBondContact O-N 2.95Å; I95-E352 HydrophobicContact CD1-CG 4.19Å; I95-E352 VanDerWaalsContact CD1-OE2 3.28Å; I95-E352 WeakPolarHBondContact CD1-OE2 3.4Å
96E98.6Very high98.1Very high122 Ų12254.9 Ų54.957%0.5728%0.28SS*.Hα-helixtrans-65.1-37.2176.7-74173.5177.700112.4K92 L93 G99K92-E96 WeakPolarHBondContact CE-OE1 3.49Å; K92-E96 HydrophobicContact CG-CG 4.35Å; K92-E96 WeakPolarHBondContact CG-OE1 3.4Å; K92-E96 IonicContact NZ-OE1 3.84Å; K92-E96 WeakPolarHBondContact O-CB 3.34Å; K92-E96 VanDerWaalsContact O-CG 3.29Å; K92-E96 WeakPolarHBondContact O-CG 3.41Å; K92-E96 PolarHBondContact O-N 2.98Å; L93-E96 PolarHBondContact O-N 3.48Å; E96-G99 PolarHBondContact O-N 3.42Å
97M98.6Very high98.1Very high43 Ų4352.1 Ų52.121%0.21227%0.267CS..Hα-helixtrans-68.3-35.4176.4-75.1174.455.300112.9T72 A76 L93 M94 I95 K105 F106T72-M97 HydrophobicContact CG2-CE 4.12Å; A76-M97 HydrophobicContact CB-CE 3.46Å; A76-M97 VanDerWaalsContact CB-CE 3.46Å; A76-M97 HydrophobicContact CB-SD 3.64Å; L93-M97 HydrophobicContact CD1-CG 4.1Å; L93-M97 HydrophobicContact CD1-SD 3.96Å; L93-M97 HydrophobicContact CG-SD 3.96Å; L93-M97 WeakPolarHBondContact O-CB 3.41Å; L93-M97 WeakPolarHBondContact O-CG 3.28Å; L93-M97 PolarHBondContact O-N 3.22Å; M94-M97 PolarHBondContact O-N 2.81Å; I95-M97 VanDerWaalsContact C-N 3.35Å; I95-M97 PolarHBondContact O-N 3.48Å; M97-K105 PolarHBondContact O-NZ 2.8Å; M97-F106 VanDerWaalsContact C-CE2 3.48Å; M97-F106 HydrophobicContact CB-CE2 3.7Å; M97-F106 HydrophobicContact CB-CZ 4.12Å; M97-F106 HydrophobicContact CE-CE2 4.47Å; M97-F106 HydrophobicContact CE-CZ 4.49Å; M97-F106 WeakPolarHBondContact O-CZ 3.47Å
98D98.7Very high98.1Very high5 Ų552.1 Ų52.13%0.02727%0.268CS..Hα-helixtrans-66-51.9170.9179.7-80.1000109.7M94 I95 T100 K103 K105 F106 I111M94-D98 PolarHBondContact O-N 3.38Å; I95-D98 PolarHBondContact O-N 3.17Å; D98-T100 VanDerWaalsContact C-N 3.26Å; D98-T100 PolarHBondContact O-N 3.13Å; D98-T100 WeakPolarHBondContact OD1-CB 3.01Å; D98-T100 PolarHBondContact OD1-N 2.9Å; D98-T100 PolarHBondContact OD1-OG1 3.25Å; D98-K103 WeakPolarHBondContact OD1-CA 3.36Å; D98-K105 WeakPolarHBondContact O-CD 3.39Å; D98-K105 WeakPolarHBondContact OD2-CB 3.29Å; D98-K105 PolarHBondContact OD2-N 2.99Å; D98-F106 HydrophobicContact CB-CD2 3.67Å; D98-F106 HydrophobicContact CB-CE2 4.02Å; D98-F106 HydrophobicContact CB-CG 4.32Å; D98-F106 VanDerWaalsContact N-CE2 3.33Å; D98-F106 PolarHBondContact OD2-N 3.48Å; D98-I111 HydrophobicContact CB-CD1 3.87Å
99G98.3Very high98.1Very high63 Ų6346.3 Ų46.365%0.64924%0.241SC*.  trans74.29.9172.300000114.9I95 E96I95-G99 PolarHBondContact O-N 2.95Å; E96-G99 PolarHBondContact O-N 3.42Å
100T98.2Very high98.1Very high46 Ų4640.7 Ų40.728%0.28222%0.217SC..SBendtrans-113.4154.517775.10000111.4D98 N102 K103 S104 K105D98-T100 VanDerWaalsContact C-N 3.26Å; D98-T100 PolarHBondContact O-N 3.13Å; D98-T100 WeakPolarHBondContact OD1-CB 3.01Å; D98-T100 PolarHBondContact OD1-N 2.9Å; D98-T100 PolarHBondContact OD1-OG1 3.25Å; T100-N102 PolarHBondContact O-N 3.03Å; T100-K103 VanDerWaalsContact OG1-CA 3.31Å; T100-K103 WeakPolarHBondContact OG1-CA 3.26Å; T100-K103 PolarHBondContact OG1-N 3.04Å; T100-K103 VanDerWaalsContact OG1-N 3.09Å; T100-S104 PolarHBondContact OG1-N 2.85Å; T100-S104 PolarHBondContact OG1-OG 3.4Å; T100-K105 HydrophobicContact CG2-CB 3.96Å
101E94.6Very high98.1Very high146 Ų14640.7 Ų40.768%0.68222%0.217SC*.THydrogen-bonded Turntrans-65-38.2-178.7-179.7168.8-161.700112.9K326E101-K326 IonicContact OE1-NZ 2.71Å; E101-K326 PolarHBondContact OE1-NZ 2.62Å
102N94.9Very high98.1Very high69 Ų6940.7 Ų40.737%0.36922%0.217SC..THydrogen-bonded Turntrans-107.818.8-174.967.5-20.2000113.3L47 T100 S104L47-N102 PolarHBondContact N-O 2.87Å; T100-N102 PolarHBondContact O-N 3.03Å; N102-S104 PolarHBondContact O-N 3Å; N102-S104 WeakPolarHBondContact OD1-CB 3.36Å; N102-S104 PolarHBondContact OD1-OG 3.47Å
103K98.3Very high98.2Very high3 Ų334.9 Ų34.91%0.01319%0.191CC..  trans58.731.4179.5-58.3173.4172.869.70113.4A46 D98 T100 K105 G107 A108 I111 I347 E352A46-K103 HydrophobicContact CB-CD 4.35Å; D98-K103 WeakPolarHBondContact OD1-CA 3.36Å; T100-K103 VanDerWaalsContact OG1-CA 3.31Å; T100-K103 WeakPolarHBondContact OG1-CA 3.26Å; T100-K103 PolarHBondContact OG1-N 3.04Å; T100-K103 VanDerWaalsContact OG1-N 3.09Å; K103-K105 VanDerWaalsContact C-N 3.35Å; K103-K105 PolarHBondContact O-N 3.2Å; K103-G107 CarbonylContact O-C 3.44Å; K103-G107 WeakPolarHBondContact O-CA 3.44Å; K103-G107 PolarHBondContact O-N 3.45Å; K103-A108 HydrophobicContact CB-CB 4.21Å; K103-A108 HydrophobicContact CD-CB 4.18Å; K103-A108 PolarHBondContact O-N 3.05Å; K103-I111 HydrophobicContact CB-CD1 4Å; K103-I111 HydrophobicContact CD-CD1 3.92Å; K103-I111 HydrophobicContact CG-CD1 3.83Å; K103-I347 WeakPolarHBondContact CD-O 3.31Å; K103-I347 WeakPolarHBondContact CE-O 3.48Å; K103-I347 PolarHBondContact NZ-O 3.23Å; K103-E352 WeakPolarHBondContact CE-OE2 3.37Å; K103-E352 IonicContact NZ-OE1 3.43Å; K103-E352 PolarHBondContact NZ-OE1 2.89Å; K103-E352 IonicContact NZ-OE2 3.6Å; K103-E352 PolarHBondContact NZ-OE2 2.94Å
104S97.7Very high98.2Very high45 Ų4533.8 Ų33.832%0.31519%0.186SC..THydrogen-bonded Turntrans-77.1-14.6-172.650.10000114.8T100 N102T100-S104 PolarHBondContact OG1-N 2.85Å; T100-S104 PolarHBondContact OG1-OG 3.4Å; N102-S104 PolarHBondContact O-N 3Å; N102-S104 WeakPolarHBondContact OD1-CB 3.36Å; N102-S104 PolarHBondContact OD1-OG 3.47Å
105K98.1Very high98.2Very high112 Ų11233.8 Ų33.849%0.48719%0.186SC..THydrogen-bonded Turntrans-76.7-47.8178-179.4-172.6177.3-173.40111.7H68 M97 D98 T100 K103H68-K105 PolarHBondContact NE2-O 2.82Å; M97-K105 PolarHBondContact O-NZ 2.8Å; D98-K105 WeakPolarHBondContact O-CD 3.39Å; D98-K105 WeakPolarHBondContact OD2-CB 3.29Å; D98-K105 PolarHBondContact OD2-N 2.99Å; T100-K105 HydrophobicContact CG2-CB 3.96Å; K103-K105 VanDerWaalsContact C-N 3.35Å; K103-K105 PolarHBondContact O-N 3.2Å
106F98.4Very high98.2Very high4 Ų431.8 Ų31.82%0.01818%0.175CC..THydrogen-bonded Turntrans-97.7-24.6178.8-61.9-28.7000113.1L49 H68 T72 I73 M97 D98 A110 I111L49-F106 WeakPolarHBondContact CD2-O 3.46Å; H68-F106 HydrophobicContact CB-CB 4.33Å; H68-F106 HydrophobicContact CB-CD1 4.08Å; H68-F106 HydrophobicContact CB-CG 4.44Å; H68-F106 AromaticContact CG-CD1 3.89Å; H68-F106 AromaticContact ND1-CD1 3.82Å; T72-F106 HydrophobicContact CG2-CE1 4.03Å; T72-F106 HydrophobicContact CG2-CZ 3.88Å; I73-F106 HydrophobicContact CD1-CD2 4.03Å; I73-F106 HydrophobicContact CD1-CG 4.41Å; I73-F106 HydrophobicContact CG1-CD2 4.19Å; I73-F106 HydrophobicContact CG1-CE2 4.22Å; M97-F106 VanDerWaalsContact C-CE2 3.48Å; M97-F106 HydrophobicContact CB-CE2 3.7Å; M97-F106 HydrophobicContact CB-CZ 4.12Å; M97-F106 HydrophobicContact CE-CE2 4.47Å; M97-F106 HydrophobicContact CE-CZ 4.49Å; M97-F106 WeakPolarHBondContact O-CZ 3.47Å; D98-F106 HydrophobicContact CB-CD2 3.67Å; D98-F106 HydrophobicContact CB-CE2 4.02Å; D98-F106 HydrophobicContact CB-CG 4.32Å; D98-F106 VanDerWaalsContact N-CE2 3.33Å; D98-F106 PolarHBondContact OD2-N 3.48Å; F106-A110 HydrophobicContact CB-CB 4.19Å; F106-A110 WeakPolarHBondContact O-CB 3.4Å; F106-I111 HydrophobicContact CB-CG1 4.44Å; F106-I111 HydrophobicContact CD2-CD1 4.49Å; F106-I111 HydrophobicContact CD2-CG1 4.46Å
107G98.4Very high98.2Very high0 Ų026 Ų260%015%0.148CC..  trans89.9135.5-164.900000111.5L47 K103 N109 A110 I111L47-G107 CarbonylContact O-C 3.54Å; L47-G107 WeakPolarHBondContact O-CA 3.23Å; K103-G107 CarbonylContact O-C 3.44Å; K103-G107 WeakPolarHBondContact O-CA 3.44Å; K103-G107 PolarHBondContact O-N 3.45Å; G107-N109 WeakPolarHBondContact CA-OD1 3.24Å; G107-N109 PolarHBondContact O-N 3.07Å; G107-A110 WeakPolarHBondContact O-CB 3.46Å; G107-A110 PolarHBondContact O-N 2.93Å; G107-I111 PolarHBondContact O-N 3.07Å
108A98.4Very high98.2Very high2 Ų224 Ų242%0.01714%0.138CC..Hα-helixtrans-58.1-34.6171.900000111.6A46 L47 K103 A110 I111 L112A46-A108 HydrophobicContact CB-CB 3.59Å; L47-A108 WeakPolarHBondContact O-CB 3.49Å; L47-A108 PolarHBondContact O-N 2.97Å; K103-A108 HydrophobicContact CB-CB 4.21Å; K103-A108 HydrophobicContact CD-CB 4.18Å; K103-A108 PolarHBondContact O-N 3.05Å; A108-A110 VanDerWaalsContact C-N 3.28Å; A108-A110 PolarHBondContact O-N 3.1Å; A108-I111 PolarHBondContact O-N 2.89Å; A108-L112 WeakPolarHBondContact O-CB 3.48Å; A108-L112 PolarHBondContact O-N 3.37Å
109N98.6Very high98.2Very high4 Ų423.7 Ų23.72%0.02114%0.137CC..Hα-helixtrans-63.8-29.517355.5-21.5000113.3V20 V35 E48 L49 G107 G113V20-N109 HydrophobicContact CG2-CB 4.3Å; V35-N109 HydrophobicContact CG1-CB 3.9Å; V35-N109 WeakPolarHBondContact CG2-O 3.39Å; E48-N109 HydrophobicContact CG-CB 4.16Å; L49-N109 PolarHBondContact N-OD1 3.17Å; L49-N109 PolarHBondContact O-ND2 3.18Å; G107-N109 WeakPolarHBondContact CA-OD1 3.24Å; G107-N109 PolarHBondContact O-N 3.07Å; N109-G113 PolarHBondContact O-N 3.02Å
110A98.8Very high98.3Very high0 Ų022.5 Ų22.50%011%0.114CC..Hα-helixtrans-72.3-48.9174.300000112.1A65 I69 I73 F106 G107 A108A65-A110 HydrophobicContact CB-CB 4.28Å; I69-A110 HydrophobicContact CD1-CB 4.18Å; I69-A110 HydrophobicContact CG1-CB 3.8Å; I73-A110 HydrophobicContact CD1-CB 4.34Å; F106-A110 HydrophobicContact CB-CB 4.19Å; F106-A110 WeakPolarHBondContact O-CB 3.4Å; G107-A110 WeakPolarHBondContact O-CB 3.46Å; G107-A110 PolarHBondContact O-N 2.93Å; A108-A110 VanDerWaalsContact C-N 3.28Å; A108-A110 PolarHBondContact O-N 3.1Å
111I98.9Very high98.3Very high0 Ų020.3 Ų20.30%010%0.1CC..Hα-helixtrans-66.4-44.8-177.8-63.2174.9000110.6M94 D98 K103 F106 G107 A108 G113 V114 S115 G348M94-I111 HydrophobicContact CB-CG1 4.49Å; M94-I111 HydrophobicContact CB-CG2 3.99Å; M94-I111 HydrophobicContact CE-CG2 4.01Å; M94-I111 HydrophobicContact SD-CG2 4.4Å; D98-I111 HydrophobicContact CB-CD1 3.87Å; K103-I111 HydrophobicContact CB-CD1 4Å; K103-I111 HydrophobicContact CD-CD1 3.92Å; K103-I111 HydrophobicContact CG-CD1 3.83Å; F106-I111 HydrophobicContact CB-CG1 4.44Å; F106-I111 HydrophobicContact CD2-CD1 4.49Å; F106-I111 HydrophobicContact CD2-CG1 4.46Å; G107-I111 PolarHBondContact O-N 3.07Å; A108-I111 PolarHBondContact O-N 2.89Å; I111-G113 PolarHBondContact O-N 3.26Å; I111-V114 PolarHBondContact O-N 3.03Å; I111-S115 WeakPolarHBondContact O-CB 3.5Å; I111-S115 PolarHBondContact O-N 3.37Å; I111-G348 WeakPolarHBondContact CG2-O 3.48Å
112L98.9Very high98.5Very high0 Ų013.4 Ų13.40%07%0.068CC..Hα-helixtrans-63-45.1-176.3-176.369.6000112.2V35 A108 V114 S115 L116 V344 N345 G348V35-L112 HydrophobicContact CG1-CD2 3.77Å; V35-L112 HydrophobicContact CG2-CB 4.33Å; V35-L112 HydrophobicContact CG2-CD2 4.27Å; V35-L112 HydrophobicContact CG2-CG 4.42Å; A108-L112 WeakPolarHBondContact O-CB 3.48Å; A108-L112 PolarHBondContact O-N 3.37Å; L112-V114 PolarHBondContact O-N 3Å; L112-S115 WeakPolarHBondContact O-CB 3.47Å; L112-S115 PolarHBondContact O-N 2.86Å; L112-S115 VanDerWaalsContact O-N 3.07Å; L112-L116 HydrophobicContact CD1-CD1 4.22Å; L112-L116 HydrophobicContact CD1-CD2 4.21Å; L112-L116 HydrophobicContact CD1-CG 4Å; L112-L116 HydrophobicContact CD2-CD1 4.24Å; L112-L116 HydrophobicContact CG-CD1 3.8Å; L112-L116 HydrophobicContact CG-CG 4.02Å; L112-L116 VanDerWaalsContact O-CG 3.26Å; L112-L116 WeakPolarHBondContact O-CG 3.35Å; L112-L116 PolarHBondContact O-N 3.25Å; L112-V344 HydrophobicContact CD1-CB 4.07Å; L112-V344 HydrophobicContact CD1-CG2 4.21Å; L112-V344 HydrophobicContact CD2-CG2 4.19Å; L112-N345 HydrophobicContact CD2-CB 3.43Å; L112-N345 VanDerWaalsContact CD2-CB 3.43Å; L112-G348 WeakPolarHBondContact CA-O 3.43Å; L112-G348 PolarHBondContact N-O 3.13Å
113G98.9Very high98.7Very high0 Ų010.2 Ų10.20%05%0.051CC..Hα-helixtrans-56.9-41.7-178.700000112V35 N109 I111 A117V35-G113 VanDerWaalsContact CG2-CA 3.49Å; N109-G113 PolarHBondContact O-N 3.02Å; I111-G113 PolarHBondContact O-N 3.26Å; G113-A117 WeakPolarHBondContact O-CB 3.35Å; G113-A117 PolarHBondContact O-N 3.19Å
114V98.9Very high98.7Very high0 Ų013.3 Ų13.30%07%0.07CC..Hα-helixtrans-69.3-45.4174.9-176.70000111.2V6 V22 I69 I73 L77 M94 I111 L112 L116 A117 V118V6-V114 HydrophobicContact CG1-CG2 4.27Å; V22-V114 HydrophobicContact CG1-CG2 4.09Å; V22-V114 HydrophobicContact CG2-CG2 4.22Å; I69-V114 HydrophobicContact CG1-CG2 4.26Å; I69-V114 HydrophobicContact CG2-CG2 3.73Å; I73-V114 HydrophobicContact CG2-CG1 4.38Å; I73-V114 HydrophobicContact CG2-CG2 4.19Å; L77-V114 HydrophobicContact CD1-CG1 3.44Å; L77-V114 VanDerWaalsContact CD1-CG1 3.44Å; M94-V114 HydrophobicContact CE-CB 4.36Å; M94-V114 HydrophobicContact CE-CG1 4.31Å; M94-V114 HydrophobicContact SD-CB 3.71Å; M94-V114 HydrophobicContact SD-CG1 3.58Å; M94-V114 VanDerWaalsContact SD-CG1 3.58Å; M94-V114 HydrophobicContact SD-CG2 4.49Å; I111-V114 PolarHBondContact O-N 3.03Å; L112-V114 PolarHBondContact O-N 3Å; V114-L116 VanDerWaalsContact C-N 3.32Å; V114-L116 PolarHBondContact O-N 2.92Å; V114-A117 PolarHBondContact O-N 3.43Å; V114-V118 HydrophobicContact CG1-CG2 4.22Å; V114-V118 WeakPolarHBondContact O-CB 3.45Å; V114-V118 VanDerWaalsContact O-CG2 3.22Å; V114-V118 WeakPolarHBondContact O-CG2 3.41Å; V114-V118 PolarHBondContact O-N 3.15Å
115S98.9Very high98.7Very high0 Ų013.7 Ų13.70%07%0.067CC..Hα-helixtrans-55.4-44.4179.2-172.20000112.7Q87 D91 I111 L112 C119 V350Q87-S115 PolarHBondContact NE2-O 3.46Å; Q87-S115 PolarHBondContact NE2-OG 2.75Å; Q87-S115 VanDerWaalsContact NE2-OG 3.17Å; D91-S115 WeakPolarHBondContact OD1-CB 3.36Å; D91-S115 PolarHBondContact OD1-OG 3.31Å; D91-S115 PolarHBondContact OD2-OG 3.01Å; I111-S115 WeakPolarHBondContact O-CB 3.5Å; I111-S115 PolarHBondContact O-N 3.37Å; L112-S115 WeakPolarHBondContact O-CB 3.47Å; L112-S115 PolarHBondContact O-N 2.86Å; L112-S115 VanDerWaalsContact O-N 3.07Å; S115-C119 PolarHBondContact O-N 2.6Å; S115-C119 VanDerWaalsContact O-N 3.1Å; S115-V350 WeakPolarHBondContact OG-CG2 3.14Å; S115-V350 PolarHBondContact OG-N 2.78Å
116L98.9Very high98.7Very high4 Ų412.6 Ų12.62%0.0216%0.063CC..Hα-helixtrans-67.2-44.8177.1-63.9173000111.9A33 L112 V114 V118 C119 K120 V350 F380A33-L116 HydrophobicContact CB-CB 3.41Å; A33-L116 VanDerWaalsContact CB-CB 3.41Å; A33-L116 HydrophobicContact CB-CD1 4.32Å; L112-L116 HydrophobicContact CD1-CD1 4.22Å; L112-L116 HydrophobicContact CD1-CD2 4.21Å; L112-L116 HydrophobicContact CD1-CG 4Å; L112-L116 HydrophobicContact CD2-CD1 4.24Å; L112-L116 HydrophobicContact CG-CD1 3.8Å; L112-L116 HydrophobicContact CG-CG 4.02Å; L112-L116 VanDerWaalsContact O-CG 3.26Å; L112-L116 WeakPolarHBondContact O-CG 3.35Å; L112-L116 PolarHBondContact O-N 3.25Å; V114-L116 VanDerWaalsContact C-N 3.32Å; V114-L116 PolarHBondContact O-N 2.92Å; L116-V118 VanDerWaalsContact C-N 3.31Å; L116-V118 PolarHBondContact O-N 3.39Å; L116-C119 WeakPolarHBondContact O-CB 3.22Å; L116-C119 PolarHBondContact O-N 3.13Å; L116-K120 WeakPolarHBondContact O-CG 3.34Å; L116-K120 PolarHBondContact O-N 2.56Å; L116-V350 HydrophobicContact CD2-CG2 3.69Å; L116-V350 HydrophobicContact CG-CG2 4.44Å; L116-F380 HydrophobicContact CB-CD2 4.43Å; L116-F380 HydrophobicContact CD2-CD1 3.45Å; L116-F380 VanDerWaalsContact CD2-CD1 3.45Å; L116-F380 HydrophobicContact CD2-CD2 3.73Å; L116-F380 HydrophobicContact CD2-CE1 3.38Å; L116-F380 HydrophobicContact CD2-CE2 3.68Å; L116-F380 HydrophobicContact CD2-CG 3.63Å; L116-F380 HydrophobicContact CD2-CZ 3.51Å
117A98.9Very high98.7Very high0 Ų015.6 Ų15.60%010%0.095CC..Hα-helixtrans-64.5-36.2178.600000112.1V22 L24 A33 G113 V114 K120 A121V22-A117 HydrophobicContact CG1-CB 4.26Å; L24-A117 HydrophobicContact CB-CB 3.85Å; A33-A117 HydrophobicContact CB-CB 4.12Å; G113-A117 WeakPolarHBondContact O-CB 3.35Å; G113-A117 PolarHBondContact O-N 3.19Å; V114-A117 PolarHBondContact O-N 3.43Å; A117-K120 PolarHBondContact O-N 3.32Å; A117-A121 WeakPolarHBondContact O-CB 3.34Å; A117-A121 PolarHBondContact O-N 3.48Å
118V98.9Very high98.7Very high0 Ų017.6 Ų17.60%011%0.107CC..Hα-helixtrans-61.2-47.2171.6169.50000110.7I3 L24 I90 V114 L116 K120 A121 G122I3-V118 HydrophobicContact CD1-CG2 4.39Å; L24-V118 HydrophobicContact CD1-CB 4.35Å; L24-V118 HydrophobicContact CD1-CG2 3.42Å; L24-V118 VanDerWaalsContact CD1-CG2 3.42Å; I90-V118 HydrophobicContact CB-CG1 4.38Å; I90-V118 HydrophobicContact CD1-CG1 3.53Å; I90-V118 HydrophobicContact CD1-CG2 4.38Å; I90-V118 HydrophobicContact CG2-CG1 4.26Å; I90-V118 HydrophobicContact CG2-CG2 3.9Å; V114-V118 HydrophobicContact CG1-CG2 4.22Å; V114-V118 WeakPolarHBondContact O-CB 3.45Å; V114-V118 VanDerWaalsContact O-CG2 3.22Å; V114-V118 WeakPolarHBondContact O-CG2 3.41Å; V114-V118 PolarHBondContact O-N 3.15Å; L116-V118 VanDerWaalsContact C-N 3.31Å; L116-V118 PolarHBondContact O-N 3.39Å; V118-K120 VanDerWaalsContact C-N 3.33Å; V118-K120 PolarHBondContact O-N 2.94Å; V118-A121 CarbonylContact O-C 3.45Å; V118-A121 WeakPolarHBondContact O-CB 3.31Å; V118-A121 PolarHBondContact O-N 2.93Å; V118-A121 VanDerWaalsContact O-N 3.14Å; V118-G122 PolarHBondContact O-N 3.4Å
119C98.9Very high98.7Very high0 Ų019.5 Ų19.50%012%0.119CC..Hα-helixtrans-60.9-42.5179.7-168.30000111.8Q87 S115 L116 A121 G122 A123 H133 V350 F380Q87-C119 VanDerWaalsContact OE1-N 3.17Å; S115-C119 PolarHBondContact O-N 2.6Å; S115-C119 VanDerWaalsContact O-N 3.1Å; L116-C119 WeakPolarHBondContact O-CB 3.22Å; L116-C119 PolarHBondContact O-N 3.13Å; C119-A121 PolarHBondContact O-N 3.17Å; C119-G122 PolarHBondContact O-N 2.95Å; C119-A123 PolarHBondContact O-N 2.99Å; C119-A123 VanDerWaalsContact O-N 3.08Å; C119-H133 PolarHBondContact O-CD2 2.89Å; C119-V350 HydrophobicContact CB-CG2 4.34Å; C119-F380 HydrophobicContact CB-CE2 3.92Å; C119-F380 HydrophobicContact CB-CZ 4.31Å
120K98.9Very high98.7Very high38 Ų3820.5 Ų20.517%0.16512%0.124CC..Hα-helixtrans-60.6-44.3173.5-68.5-179.6-173.2-173.10112.2F31 R32 L116 A117 V118 A123 V124 L130 D378F31-K120 HydrophobicContact CB-CB 4.22Å; F31-K120 HydrophobicContact CD1-CB 4.39Å; R32-K120 WeakPolarHBondContact O-CD 3.45Å; R32-K120 WeakPolarHBondContact O-CE 3.47Å; R32-K120 PolarHBondContact O-NZ 3.09Å; L116-K120 WeakPolarHBondContact O-CG 3.34Å; L116-K120 PolarHBondContact O-N 2.56Å; A117-K120 PolarHBondContact O-N 3.32Å; V118-K120 VanDerWaalsContact C-N 3.33Å; V118-K120 PolarHBondContact O-N 2.94Å; K120-A123 PolarHBondContact O-N 3.29Å; K120-V124 PolarHBondContact O-N 3.35Å; K120-L130 HydrophobicContact CG-CD1 4.38Å; K120-L130 HydrophobicContact CG-CD2 4.02Å; K120-D378 IonicContact NZ-OD1 3.69Å; K120-D378 PolarHBondContact NZ-OD1 2.98Å; K120-D378 IonicContact NZ-OD2 3.94Å; K120-D378 PolarHBondContact NZ-OD2 3.1Å
121A98.8Very high98.8Very high0 Ų021.2 Ų21.20%013%0.127CC..Hα-helixtrans-65.2-38.6175.800000112.5L24 T26 F31 V84 A117 V118 C119 A123 V124 E125L24-A121 HydrophobicContact CD2-CB 3.78Å; T26-A121 HydrophobicContact CG2-CB 4.18Å; F31-A121 HydrophobicContact CB-CB 4.17Å; F31-A121 HydrophobicContact CD1-CB 4.11Å; F31-A121 HydrophobicContact CD2-CB 3.42Å; F31-A121 VanDerWaalsContact CD2-CB 3.42Å; F31-A121 HydrophobicContact CE1-CB 4.45Å; F31-A121 HydrophobicContact CE2-CB 3.82Å; F31-A121 HydrophobicContact CG-CB 3.59Å; F31-A121 HydrophobicContact CZ-CB 4.31Å; V84-A121 HydrophobicContact CB-CB 3.98Å; V84-A121 HydrophobicContact CG1-CB 4Å; V84-A121 HydrophobicContact CG2-CB 4.12Å; A117-A121 WeakPolarHBondContact O-CB 3.34Å; A117-A121 PolarHBondContact O-N 3.48Å; V118-A121 CarbonylContact O-C 3.45Å; V118-A121 WeakPolarHBondContact O-CB 3.31Å; V118-A121 PolarHBondContact O-N 2.93Å; V118-A121 VanDerWaalsContact O-N 3.14Å; C119-A121 PolarHBondContact O-N 3.17Å; A121-A123 VanDerWaalsContact C-N 3.31Å; A121-A123 PolarHBondContact O-N 3.19Å; A121-V124 PolarHBondContact O-N 2.88Å; A121-E125 WeakPolarHBondContact O-CB 3.19Å; A121-E125 PolarHBondContact O-N 2.93Å
122G98.8Very high98.7Very high0 Ų023.7 Ų23.70%014%0.136CC..Hα-helixtrans-61.2-37.1176.500000113.1V118 C119 K126V118-G122 PolarHBondContact O-N 3.4Å; C119-G122 PolarHBondContact O-N 2.95Å; G122-K126 PolarHBondContact O-N 2.95Å; G122-K126 VanDerWaalsContact O-N 3.13Å
123A98.8Very high98.7Very high3 Ų323.7 Ų23.73%0.02514%0.136CC..Hα-helixtrans-63.8-49.717500000112.2C119 K120 A121 E125 K126 G127 V128 L130 H133C119-A123 PolarHBondContact O-N 2.99Å; C119-A123 VanDerWaalsContact O-N 3.08Å; K120-A123 PolarHBondContact O-N 3.29Å; A121-A123 VanDerWaalsContact C-N 3.31Å; A121-A123 PolarHBondContact O-N 3.19Å; A123-E125 PolarHBondContact O-N 3.39Å; A123-K126 CarbonylContact O-C 3.32Å; A123-K126 PolarHBondContact O-N 3.37Å; A123-G127 PolarHBondContact O-N 3.42Å; A123-V128 CarbonylContact C-O 3.56Å; A123-V128 PolarHBondContact O-N 3.05Å; A123-V128 VanDerWaalsContact O-N 3.09Å; A123-V128 VanDerWaalsContact O-O 3.14Å; A123-L130 HydrophobicContact CB-CB 4.35Å; A123-L130 HydrophobicContact CB-CD1 4.16Å; A123-H133 HydrophobicContact CB-CB 3.52Å
124V98.6Very high98.7Very high68 Ų6823.7 Ų23.741%0.41214%0.136SC..Hα-helixtrans-68.8-34.3179.8173.50000112.2K28 F31 K120 A121 K126 G127K28-V124 HydrophobicContact CB-CG1 4.01Å; K28-V124 HydrophobicContact CG-CG1 4.45Å; F31-V124 HydrophobicContact CD1-CG2 4.43Å; F31-V124 HydrophobicContact CE1-CB 3.54Å; F31-V124 HydrophobicContact CE1-CG1 3.92Å; F31-V124 HydrophobicContact CE1-CG2 3.59Å; F31-V124 HydrophobicContact CZ-CB 3.91Å; F31-V124 HydrophobicContact CZ-CG1 3.94Å; F31-V124 HydrophobicContact CZ-CG2 4.42Å; K120-V124 PolarHBondContact O-N 3.35Å; A121-V124 PolarHBondContact O-N 2.88Å; V124-K126 VanDerWaalsContact C-N 3.28Å; V124-K126 PolarHBondContact O-N 3.47Å; V124-G127 PolarHBondContact O-N 2.82Å
125E98.3Very high98.7Very high53 Ų5323.7 Ų23.725%0.24814%0.136CC..Hα-helixtrans-61-38.3172.217764.5174.100112M1 V84 T85 A121 A123 G127M1-E125 WeakPolarHBondContact CA-OE1 3.33Å; M1-E125 HydrophobicContact CB-CG 4.31Å; M1-E125 WeakPolarHBondContact CB-OE1 3.4Å; M1-E125 VanDerWaalsContact CB-OE2 3.26Å; M1-E125 WeakPolarHBondContact CB-OE2 3.35Å; M1-E125 VanDerWaalsContact CE-OE2 3.28Å; M1-E125 WeakPolarHBondContact CE-OE2 3.19Å; M1-E125 PolarHBondContact N-OE1 3.14Å; V84-E125 HydrophobicContact CG2-CB 3.86Å; V84-E125 HydrophobicContact CG2-CG 4.15Å; T85-E125 HydrophobicContact CG2-CB 4.01Å; T85-E125 HydrophobicContact CG2-CG 3.64Å; A121-E125 WeakPolarHBondContact O-CB 3.19Å; A121-E125 PolarHBondContact O-N 2.93Å; A123-E125 PolarHBondContact O-N 3.39Å; E125-G127 VanDerWaalsContact C-N 3.29Å
126K98.1Very high98.7Very high89 Ų8926.8 Ų26.839%0.38715%0.153SC..Hα-helixtrans-77.9-10.2174-75.2-168.8-178.8-178.70113.9T85 G122 A123 V124 V128 D136T85-K126 HydrophobicContact CG2-CG 3.91Å; G122-K126 PolarHBondContact O-N 2.95Å; G122-K126 VanDerWaalsContact O-N 3.13Å; A123-K126 CarbonylContact O-C 3.32Å; A123-K126 PolarHBondContact O-N 3.37Å; V124-K126 VanDerWaalsContact C-N 3.28Å; V124-K126 PolarHBondContact O-N 3.47Å; K126-V128 VanDerWaalsContact C-N 3.34Å; K126-V128 HydrophobicContact CB-CG2 3.9Å; K126-D136 IonicContact NZ-OD2 3.18Å; K126-D136 PolarHBondContact NZ-OD2 2.89Å
127G98.2Very high98.7Very high67 Ų6728.8 Ų28.869%0.69116%0.163SC*.THydrogen-bonded Turntrans67.731.1-175.500000113.7A123 V124 E125A123-G127 PolarHBondContact O-N 3.42Å; V124-G127 PolarHBondContact O-N 2.82Å; E125-G127 VanDerWaalsContact C-N 3.29Å
128V98.7Very high98.7Very high42 Ų4229.2 Ų29.226%0.25517%0.167SC..SBendtrans-125.6157.4179.6-600000111.5A123 K126 R132 H133A123-V128 CarbonylContact C-O 3.56Å; A123-V128 PolarHBondContact O-N 3.05Å; A123-V128 VanDerWaalsContact O-N 3.09Å; A123-V128 VanDerWaalsContact O-O 3.14Å; K126-V128 VanDerWaalsContact C-N 3.34Å; K126-V128 HydrophobicContact CB-CG2 3.9Å; V128-R132 HydrophobicContact CB-CB 4.17Å; V128-R132 HydrophobicContact CB-CG 4.06Å; V128-R132 HydrophobicContact CG1-CG 4.36Å; V128-R132 HydrophobicContact CG2-CB 4.34Å; V128-R132 HydrophobicContact CG2-CG 4.36Å; V128-H133 HydrophobicContact CG2-CB 3.99Å
129P98.8Very high98.6Very high42 Ų4232.3 Ų32.327%0.27320%0.199SC..  trans-59.3155.6170-24.435.6000112.3Y131 R132 H133 E416P129-Y131 HydrophobicContact CB-CD1 3.65Å; P129-Y131 HydrophobicContact CB-CE1 3.25Å; P129-Y131 HydrophobicContact CB-CE2 4.43Å; P129-Y131 HydrophobicContact CB-CG 4.4Å; P129-Y131 HydrophobicContact CG-CE1 3.88Å; P129-Y131 PolarHBondContact O-N 3.37Å; P129-R132 WeakPolarHBondContact O-CB 3.31Å; P129-R132 PolarHBondContact O-N 3.22Å; P129-R132 VanDerWaalsContact O-N 3.09Å; P129-H133 PolarHBondContact O-N 3.14Å; P129-E416 WeakPolarHBondContact CG-OE1 3.17Å
130L98.9Very high98.6Very high25 Ų2533.6 Ų33.613%0.13121%0.206CC..Hα-helixtrans-60.8-45.3-176.4175.363.4000112.1K120 A123 R132 H133 I134 F380 D383K120-L130 HydrophobicContact CG-CD1 4.38Å; K120-L130 HydrophobicContact CG-CD2 4.02Å; A123-L130 HydrophobicContact CB-CB 4.35Å; A123-L130 HydrophobicContact CB-CD1 4.16Å; L130-R132 PolarHBondContact O-N 2.92Å; L130-H133 WeakPolarHBondContact O-CB 3.32Å; L130-H133 PolarHBondContact O-N 3.5Å; L130-H133 VanDerWaalsContact O-N 3.1Å; L130-I134 HydrophobicContact CD1-CD1 3.97Å; L130-I134 HydrophobicContact CD1-CG1 4.09Å; L130-I134 HydrophobicContact CG-CD1 3.86Å; L130-I134 HydrophobicContact CG-CG1 4.39Å; L130-I134 WeakPolarHBondContact O-CG1 3.47Å; L130-I134 PolarHBondContact O-N 3.18Å; L130-F380 HydrophobicContact CD1-CE2 4.32Å; L130-F380 HydrophobicContact CD2-CD2 3.86Å; L130-F380 HydrophobicContact CD2-CE2 4.2Å; L130-D383 HydrophobicContact CB-CB 4.04Å; L130-D383 WeakPolarHBondContact CB-OD1 3.18Å; L130-D383 HydrophobicContact CD2-CB 3.72Å; L130-D383 HydrophobicContact CG-CB 3.71Å
131Y98.9Very high98.4Very high14 Ų1437.1 Ų37.16%0.05524%0.235CC..Hα-helixtrans-56.1-3517666.8-98.7000112.9P129 A135 V143 D383 V386 G387 I413 L417P129-Y131 HydrophobicContact CB-CD1 3.65Å; P129-Y131 HydrophobicContact CB-CE1 3.25Å; P129-Y131 HydrophobicContact CB-CE2 4.43Å; P129-Y131 HydrophobicContact CB-CG 4.4Å; P129-Y131 HydrophobicContact CG-CE1 3.88Å; P129-Y131 PolarHBondContact O-N 3.37Å; Y131-A135 WeakPolarHBondContact O-CB 3.28Å; Y131-A135 PolarHBondContact O-N 3.42Å; Y131-V143 HydrophobicContact CD2-CG1 4.23Å; Y131-V143 HydrophobicContact CD2-CG2 4.49Å; Y131-V143 HydrophobicContact CE2-CG2 4.43Å; Y131-D383 WeakPolarHBondContact CA-O 3.47Å; Y131-D383 WeakPolarHBondContact CB-O 3.42Å; Y131-D383 PolarHBondContact N-OD1 3.1Å; Y131-V386 HydrophobicContact CD2-CG1 4.05Å; Y131-V386 HydrophobicContact CG-CG1 4.13Å; Y131-G387 VanDerWaalsContact O-CA 3.23Å; Y131-G387 WeakPolarHBondContact O-CA 3.34Å; Y131-I413 HydrophobicContact CD1-CB 4.43Å; Y131-I413 HydrophobicContact CD1-CD1 4.06Å; Y131-I413 HydrophobicContact CD1-CG1 3.8Å; Y131-I413 HydrophobicContact CD1-CG2 3.83Å; Y131-I413 HydrophobicContact CE1-CB 4.48Å; Y131-I413 HydrophobicContact CE1-CG1 4.13Å; Y131-I413 HydrophobicContact CE1-CG2 3.88Å; Y131-I413 HydrophobicContact CG-CG2 4.2Å; Y131-L417 HydrophobicContact CE2-CD2 3.95Å
132R98.8Very high98.3Very high52 Ų5241.8 Ų41.820%0.19626%0.257CS..Hα-helixtrans-73.8-41.2178-175.760.4-95.5166-5.7111.1V128 P129 L130 I134 A135 D136 N140 S141V128-R132 HydrophobicContact CB-CB 4.17Å; V128-R132 HydrophobicContact CB-CG 4.06Å; V128-R132 HydrophobicContact CG1-CG 4.36Å; V128-R132 HydrophobicContact CG2-CB 4.34Å; V128-R132 HydrophobicContact CG2-CG 4.36Å; P129-R132 WeakPolarHBondContact O-CB 3.31Å; P129-R132 PolarHBondContact O-N 3.22Å; P129-R132 VanDerWaalsContact O-N 3.09Å; L130-R132 PolarHBondContact O-N 2.92Å; R132-I134 VanDerWaalsContact C-N 3.33Å; R132-I134 PolarHBondContact O-N 2.89Å; R132-A135 PolarHBondContact O-N 2.98Å; R132-D136 IonicContact CZ-OD1 3.87Å; R132-D136 VanDerWaalsContact CZ-OD1 3.3Å; R132-D136 IonicContact NE-OD1 2.99Å; R132-D136 PolarHBondContact NE-OD1 2.91Å; R132-D136 IonicContact NH2-OD1 3.36Å; R132-D136 PolarHBondContact NH2-OD1 3.45Å; R132-D136 VanDerWaalsContact O-CG 3.29Å; R132-D136 PolarHBondContact O-N 3.13Å; R132-N140 PolarHBondContact NH2-O 3.38Å; R132-S141 PolarHBondContact NH1-O 3.42Å
133H98.9Very high98.2Very high0 Ų042.5 Ų42.50%026%0.261CS..Hα-helixtrans-59.9-44.4173.2-177.958.3000112C119 A123 V128 P129 L130 D136 L137C119-H133 PolarHBondContact O-CD2 2.89Å; A123-H133 HydrophobicContact CB-CB 3.52Å; V128-H133 HydrophobicContact CG2-CB 3.99Å; P129-H133 PolarHBondContact O-N 3.14Å; L130-H133 WeakPolarHBondContact O-CB 3.32Å; L130-H133 PolarHBondContact O-N 3.5Å; L130-H133 VanDerWaalsContact O-N 3.1Å; H133-D136 WeakPolarHBondContact O-CB 3.29Å; H133-D136 PolarHBondContact O-N 2.85Å; H133-L137 WeakPolarHBondContact O-CG 3.48Å; H133-L137 PolarHBondContact O-N 3.11Å
134I98.9Very high98.2Very high0 Ų042.7 Ų42.70%026%0.262CS..Hα-helixtrans-62.4-44.3175.8-68.5172.6000110.6L130 R132 D136 L137 A138 L354 F380 D383 L384 L388L130-I134 HydrophobicContact CD1-CD1 3.97Å; L130-I134 HydrophobicContact CD1-CG1 4.09Å; L130-I134 HydrophobicContact CG-CD1 3.86Å; L130-I134 HydrophobicContact CG-CG1 4.39Å; L130-I134 WeakPolarHBondContact O-CG1 3.47Å; L130-I134 PolarHBondContact O-N 3.18Å; R132-I134 VanDerWaalsContact C-N 3.33Å; R132-I134 PolarHBondContact O-N 2.89Å; I134-D136 VanDerWaalsContact C-N 3.29Å; I134-D136 PolarHBondContact O-N 3.38Å; I134-L137 PolarHBondContact O-N 3.16Å; I134-A138 WeakPolarHBondContact O-CB 3.41Å; I134-A138 PolarHBondContact O-N 2.85Å; I134-L354 HydrophobicContact CG2-CD2 4.19Å; I134-F380 HydrophobicContact CD1-CE1 4.38Å; I134-F380 HydrophobicContact CD1-CE2 4.2Å; I134-F380 HydrophobicContact CD1-CZ 3.92Å; I134-D383 HydrophobicContact CD1-CB 4.22Å; I134-L384 HydrophobicContact CD1-CB 4.28Å; I134-L384 HydrophobicContact CD1-CD1 4.26Å; I134-L384 HydrophobicContact CG2-CD1 3.91Å; I134-L388 HydrophobicContact CG2-CG 4.47Å
135A98.8Very high98.2Very high0 Ų039.5 Ų39.50%024%0.242CC..Hα-helixtrans-59.3-39.5175.600000112.3Y131 R132 A138 G139 N140 V143 G387Y131-A135 WeakPolarHBondContact O-CB 3.28Å; Y131-A135 PolarHBondContact O-N 3.42Å; R132-A135 PolarHBondContact O-N 2.98Å; A135-A138 CarbonylContact O-C 3.56Å; A135-A138 PolarHBondContact O-N 3.23Å; A135-G139 PolarHBondContact O-N 2.75Å; A135-N140 HydrophobicContact CB-CB 4.19Å; A135-N140 PolarHBondContact O-N 3.36Å; A135-V143 HydrophobicContact CB-CG1 3.86Å; A135-G387 VanDerWaalsContact CA-O 3.3Å; A135-G387 WeakPolarHBondContact CA-O 3.39Å; A135-G387 WeakPolarHBondContact CB-O 3.44Å
136D98.6Very high98.3Very high66 Ų6637 Ų3735%0.35323%0.23SC..Hα-helixtrans-63-44.5174.5-62.7-9000112K126 R132 H133 I134 A138 G139K126-D136 IonicContact NZ-OD2 3.18Å; K126-D136 PolarHBondContact NZ-OD2 2.89Å; R132-D136 IonicContact CZ-OD1 3.87Å; R132-D136 VanDerWaalsContact CZ-OD1 3.3Å; R132-D136 IonicContact NE-OD1 2.99Å; R132-D136 PolarHBondContact NE-OD1 2.91Å; R132-D136 IonicContact NH2-OD1 3.36Å; R132-D136 PolarHBondContact NH2-OD1 3.45Å; R132-D136 VanDerWaalsContact O-CG 3.29Å; R132-D136 PolarHBondContact O-N 3.13Å; H133-D136 WeakPolarHBondContact O-CB 3.29Å; H133-D136 PolarHBondContact O-N 2.85Å; I134-D136 VanDerWaalsContact C-N 3.29Å; I134-D136 PolarHBondContact O-N 3.38Å; D136-A138 VanDerWaalsContact C-N 3.27Å; D136-A138 PolarHBondContact O-N 2.92Å; D136-G139 PolarHBondContact O-N 3.48Å; D136-G139 VanDerWaalsContact O-N 3.13Å
137L98.6Very high98.3Very high45 Ų4532.7 Ų32.724%0.23621%0.212CC..Hα-helixtrans-63.6-35.9176.5-66.4173000111.4Q87 H133 I134 G139 L354 K358Q87-L137 HydrophobicContact CB-CD1 3.98Å; Q87-L137 HydrophobicContact CB-CD2 4.02Å; Q87-L137 HydrophobicContact CG-CD1 4.13Å; H133-L137 WeakPolarHBondContact O-CG 3.48Å; H133-L137 PolarHBondContact O-N 3.11Å; I134-L137 PolarHBondContact O-N 3.16Å; L137-G139 VanDerWaalsContact C-N 3.3Å; L137-L354 HydrophobicContact CB-CD1 3.58Å; L137-L354 HydrophobicContact CD1-CD1 4.35Å; L137-K358 PolarHBondContact O-NZ 3.11Å
138A98.1Very high98.3Very high9 Ų929.5 Ų29.57%0.07418%0.179CC..Hα-helixtrans-75.2-17.8175.500000112.9I134 A135 D136 K358 L388I134-A138 WeakPolarHBondContact O-CB 3.41Å; I134-A138 PolarHBondContact O-N 2.85Å; A135-A138 CarbonylContact O-C 3.56Å; A135-A138 PolarHBondContact O-N 3.23Å; D136-A138 VanDerWaalsContact C-N 3.27Å; D136-A138 PolarHBondContact O-N 2.92Å; A138-K358 WeakPolarHBondContact O-CE 3.25Å; A138-K358 PolarHBondContact O-NZ 3.43Å; A138-L388 HydrophobicContact CB-CD2 3.9Å
139G97.8Very high98.3Very high65 Ų6527.5 Ų27.567%0.6717%0.167SC*.THydrogen-bonded Turntrans77.221-174.300000113.7A135 D136 L137A135-G139 PolarHBondContact O-N 2.75Å; D136-G139 PolarHBondContact O-N 3.48Å; D136-G139 VanDerWaalsContact O-N 3.13Å; L137-G139 VanDerWaalsContact C-N 3.3Å
140N97.4Very high98.4Very high28 Ų2825.5 Ų25.515%0.1515%0.154CC..  trans-88.9122.8178.8-69.4-26.7000110R132 A135 G387 L388R132-N140 PolarHBondContact NH2-O 3.38Å; A135-N140 HydrophobicContact CB-CB 4.19Å; A135-N140 PolarHBondContact O-N 3.36Å; N140-G387 PolarHBondContact ND2-O 3.32Å; N140-L388 VanDerWaalsContact ND2-C 3.34Å; N140-L388 PolarHBondContact ND2-O 3.02Å
141S95.9Very high98.3Very high112 Ų11224.4 Ų24.478%0.78315%0.148SC*.SBendtrans-78.8-31.8178.853.20000113.2R132R132-S141 PolarHBondContact NH1-O 3.42Å
142E95.5Very high98.3Very high98 Ų9823.7 Ų23.746%0.45815%0.145SC..SBendtrans-107.1176.3175.5-58.2-166.8132.200110.7C389 K422E142-C389 PolarHBondContact O-SG 3.12Å; E142-K422 IonicContact OE1-NZ 2.76Å; E142-K422 PolarHBondContact OE1-NZ 3.45Å; E142-K422 IonicContact OE2-NZ 2.7Å; E142-K422 PolarHBondContact OE2-NZ 3.28Å
143V98.1Very high98.3Very high14 Ų1421.2 Ų21.29%0.08514%0.136CC..  trans-134.9150.5172.6-66.10000110.3Y131 A135 V386 C389 L417Y131-V143 HydrophobicContact CD2-CG1 4.23Å; Y131-V143 HydrophobicContact CD2-CG2 4.49Å; Y131-V143 HydrophobicContact CE2-CG2 4.43Å; A135-V143 HydrophobicContact CB-CG1 3.86Å; V143-V386 HydrophobicContact CB-CG1 3.71Å; V143-V386 HydrophobicContact CG1-CG1 4.25Å; V143-V386 HydrophobicContact CG2-CG1 4.15Å; V143-C389 VanDerWaalsContact CA-SG 3.57Å; V143-L417 HydrophobicContact CG2-CD1 3.81Å; V143-L417 HydrophobicContact CG2-CD2 3.7Å; V143-L417 HydrophobicContact CG2-CG 4.44Å
144I98.6Very high98.2Very high8 Ų821.2 Ų21.24%0.04114%0.136CC..  trans-129.5134.1-177-57.8-64.5000109.9V386 C389 K422 A424 P431 L432I144-V386 WeakPolarHBondContact O-CA 3.19Å; I144-C389 HydrophobicContact CB-CB 4.4Å; I144-C389 HydrophobicContact CG1-CB 4.12Å; I144-K422 HydrophobicContact CD1-CB 3.68Å; I144-K422 HydrophobicContact CD1-CD 3.94Å; I144-K422 HydrophobicContact CD1-CG 4.44Å; I144-A424 HydrophobicContact CG2-CB 3.89Å; I144-P431 HydrophobicContact CB-CB 4.5Å; I144-P431 HydrophobicContact CG1-CB 4.28Å; I144-P431 HydrophobicContact CG2-CB 3.85Å; I144-P431 HydrophobicContact CG2-CG 4.45Å; I144-L432 HydrophobicContact CD1-CD2 4.18Å; I144-L432 HydrophobicContact CG1-CD2 3.8Å
145L98.9Very high98Very high0 Ų021.2 Ų21.20%014%0.136CC..BIsolated β-bridgetrans-77.8133.9168.1-74164.4000111F178 V386 L410 I413 E414 A421 K422 F423 A424L145-F178 HydrophobicContact CB-CB 4.29Å; L145-F178 HydrophobicContact CD1-CB 4.03Å; L145-F178 HydrophobicContact CD2-CB 4.49Å; L145-V386 HydrophobicContact CD2-CG2 4.03Å; L145-L410 HydrophobicContact CD2-CD2 4.34Å; L145-I413 HydrophobicContact CD2-CG2 4.35Å; L145-E414 HydrophobicContact CD1-CB 3.44Å; L145-E414 VanDerWaalsContact CD1-CB 3.44Å; L145-E414 HydrophobicContact CD1-CG 3.47Å; L145-E414 VanDerWaalsContact CD1-CG 3.47Å; L145-E414 WeakPolarHBondContact CD1-OE1 3.39Å; L145-E414 HydrophobicContact CD2-CB 4.22Å; L145-E414 HydrophobicContact CG-CB 4.47Å; L145-A421 HydrophobicContact CD1-CB 4Å; L145-K422 PolarHBondContact N-O 3.04Å; L145-F423 HydrophobicContact CB-CD2 4.28Å; L145-A424 PolarHBondContact O-N 2.95Å
146P98.9Very high97.8Very high0 Ų021.4 Ų21.40%014%0.137CC..PPolyproline II helixtrans-81.1157-174.335.6-38.9000112.6P148 F178 V385 G391 I393 L410 F423P146-P148 WeakPolarHBondContact O-CD 3.46Å; P146-F178 HydrophobicContact CG-CE2 4.47Å; P146-F178 VanDerWaalsContact O-CD2 3.31Å; P146-F178 WeakPolarHBondContact O-CD2 3.35Å; P146-V385 HydrophobicContact CB-CG1 4.36Å; P146-V385 HydrophobicContact CB-CG2 3.7Å; P146-V385 HydrophobicContact CG-CG1 3.72Å; P146-V385 HydrophobicContact CG-CG2 4.01Å; P146-G391 CarbonylContact C-O 3.43Å; P146-G391 VanDerWaalsContact CA-C 3.47Å; P146-G391 WeakPolarHBondContact CA-O 3.36Å; P146-I393 HydrophobicContact CB-CB 4.24Å; P146-I393 HydrophobicContact CB-CG2 3.88Å; P146-I393 HydrophobicContact CG-CB 4.19Å; P146-I393 HydrophobicContact CG-CG2 3.54Å; P146-L410 HydrophobicContact CG-CD1 4Å; P146-L410 HydrophobicContact CG-CD2 4.06Å; P146-F423 WeakPolarHBondContact O-CE2 3.5Å
147V98.9Very high97.4Very high0 Ų020.6 Ų20.60%014%0.137CC..EExtended strand (participates in β ladder)trans-71.6125.3156.7178.30000108.7L171 V173 G391 Q392 I393 F423 A424 G425 F428V147-L171 HydrophobicContact CG1-CB 3.99Å; V147-L171 HydrophobicContact CG1-CD2 4.45Å; V147-V173 HydrophobicContact CG1-CG1 4.01Å; V147-V173 HydrophobicContact CG2-CG1 4.39Å; V147-G391 PolarHBondContact N-O 3.23Å; V147-Q392 WeakPolarHBondContact O-CA 3.4Å; V147-I393 PolarHBondContact O-N 2.98Å; V147-I393 VanDerWaalsContact O-N 3.1Å; V147-F423 HydrophobicContact CB-CZ 4.45Å; V147-F423 HydrophobicContact CG2-CE1 4.34Å; V147-F423 HydrophobicContact CG2-CE2 4.17Å; V147-F423 HydrophobicContact CG2-CZ 3.75Å; V147-A424 HydrophobicContact CG2-CB 4.42Å; V147-G425 VanDerWaalsContact CG2-O 3.22Å; V147-G425 WeakPolarHBondContact CG2-O 3.18Å; V147-F428 HydrophobicContact CB-CB 4.03Å; V147-F428 HydrophobicContact CG2-CB 3.71Å
148P98.9Very high96.8Very high0 Ų018.9 Ų18.90%013%0.128CC..EExtended strand (participates in β ladder)trans-76129.3171.830.4-33.3000110.9P146 F150 P172 F178 A181 Y407P146-P148 WeakPolarHBondContact O-CD 3.46Å; P148-F150 HydrophobicContact CB-CD1 4.41Å; P148-F150 HydrophobicContact CB-CD2 4.29Å; P148-F150 HydrophobicContact CB-CE1 3.82Å; P148-F150 HydrophobicContact CB-CE2 3.7Å; P148-F150 HydrophobicContact CB-CZ 3.43Å; P148-F150 VanDerWaalsContact CB-CZ 3.43Å; P148-F150 HydrophobicContact CG-CD2 4.29Å; P148-F150 HydrophobicContact CG-CE1 4.22Å; P148-F150 HydrophobicContact CG-CE2 3.37Å; P148-F150 HydrophobicContact CG-CZ 3.32Å; P148-P172 WeakPolarHBondContact O-CD 3.5Å; P148-F178 HydrophobicContact CB-CE2 4.15Å; P148-F178 HydrophobicContact CG-CE2 3.96Å; P148-A181 HydrophobicContact CG-CB 4.03Å; P148-Y407 HydrophobicContact CB-CD1 4.27Å; P148-Y407 HydrophobicContact CB-CE1 3.63Å
149A98.9Very high96.4Very high0 Ų019 Ų190%013%0.129CC..EExtended strand (participates in β ladder)trans-96.298.6167.200000108.9N151 M169 L171 M368 I393 K394A149-N151 PolarHBondContact O-N 3Å; A149-M169 HydrophobicContact CB-CB 4.41Å; A149-M169 HydrophobicContact CB-SD 3.76Å; A149-L171 HydrophobicContact CB-CD1 4.06Å; A149-L171 HydrophobicContact CB-CD2 4.13Å; A149-L171 HydrophobicContact CB-CG 3.82Å; A149-M368 HydrophobicContact CB-CE 4.49Å; A149-M368 HydrophobicContact CB-SD 4.48Å; A149-I393 PolarHBondContact N-O 2.8Å; A149-K394 HydrophobicContact CB-CB 4.09Å
150F98.9Very high95.9Very high0 Ų020.4 Ų20.40%014%0.143CC..EExtended strand (participates in β ladder)trans-85.5114.3-176.2-60.1-74.1000110.7P148 V152 M169 I170 P172 M182 G396 P398 Y407P148-F150 HydrophobicContact CB-CD1 4.41Å; P148-F150 HydrophobicContact CB-CD2 4.29Å; P148-F150 HydrophobicContact CB-CE1 3.82Å; P148-F150 HydrophobicContact CB-CE2 3.7Å; P148-F150 HydrophobicContact CB-CZ 3.43Å; P148-F150 VanDerWaalsContact CB-CZ 3.43Å; P148-F150 HydrophobicContact CG-CD2 4.29Å; P148-F150 HydrophobicContact CG-CE1 4.22Å; P148-F150 HydrophobicContact CG-CE2 3.37Å; P148-F150 HydrophobicContact CG-CZ 3.32Å; F150-V152 HydrophobicContact CB-CG1 3.91Å; F150-V152 WeakPolarHBondContact O-CG1 3.39Å; F150-V152 PolarHBondContact O-N 2.81Å; F150-V152 VanDerWaalsContact O-N 3.12Å; F150-M169 CarbonylContact O-C 3.55Å; F150-M169 WeakPolarHBondContact O-CA 3.43Å; F150-I170 HydrophobicContact CB-CG1 3.86Å; F150-I170 HydrophobicContact CD2-CG1 4.13Å; F150-I170 HydrophobicContact CG-CG1 4.49Å; F150-I170 PolarHBondContact N-O 2.92Å; F150-I170 PolarHBondContact O-N 3.07Å; F150-P172 HydrophobicContact CD2-CG 4.28Å; F150-P172 HydrophobicContact CE2-CG 3.9Å; F150-M182 HydrophobicContact CE1-CE 4.02Å; F150-M182 HydrophobicContact CE1-SD 3.64Å; F150-M182 HydrophobicContact CZ-CE 4.18Å; F150-M182 HydrophobicContact CZ-SD 3.46Å; F150-M182 WeakPolarHBondContact CZ-SD 3.34Å; F150-G396 WeakPolarHBondContact CA-O 3.5Å; F150-P398 HydrophobicContact CD1-CB 4.39Å; F150-P398 HydrophobicContact CD1-CG 4.43Å; F150-P398 HydrophobicContact CE1-CB 4.43Å; F150-Y407 HydrophobicContact CD1-CE1 4.08Å; F150-Y407 AromaticContact CD1-CE2 3.74Å; F150-Y407 HydrophobicContact CD1-CE2 3.74Å; F150-Y407 AromaticContact CD1-CZ 3.48Å; F150-Y407 VanDerWaalsContact CD1-CZ 3.48Å; F150-Y407 WeakPolarHBondContact CD1-OH 3.28Å; F150-Y407 HydrophobicContact CE1-CD1 4.02Å; F150-Y407 HydrophobicContact CE1-CD2 4.09Å; F150-Y407 AromaticContact CE1-CE1 3.62Å; F150-Y407 HydrophobicContact CE1-CE1 3.62Å; F150-Y407 AromaticContact CE1-CE2 3.7Å; F150-Y407 HydrophobicContact CE1-CE2 3.7Å; F150-Y407 HydrophobicContact CE1-CG 4.24Å; F150-Y407 AromaticContact CE1-CZ 3.45Å; F150-Y407 VanDerWaalsContact CE1-CZ 3.45Å; F150-Y407 HydrophobicContact CZ-CE1 4.42Å
151N98.6Very high95.6Very high1 Ų119.5 Ų19.51%0.00514%0.139CC..EExtended strand (participates in β ladder)trans-72.499.2173.7-173.45.2000110.8A149 I153 N154 E167 M169 E210 G212 A397A149-N151 PolarHBondContact O-N 3Å; N151-I153 PolarHBondContact OD1-O 2.94Å; N151-I153 VanDerWaalsContact OD1-O 3.1Å; N151-N154 PolarHBondContact ND2-ND2 2.84Å; N151-N154 PolarHBondContact OD1-ND2 3.5Å; N151-E167 VanDerWaalsContact ND2-CG 3.28Å; N151-E167 WeakPolarHBondContact ND2-CG 3.26Å; N151-E167 WeakPolarHBondContact OD1-CA 3.13Å; N151-E167 WeakPolarHBondContact OD1-CB 3.35Å; N151-M169 HydrophobicContact CB-CG 4.09Å; N151-E210 PolarHBondContact ND2-OE2 2.77Å; N151-G212 WeakPolarHBondContact O-CA 3.42Å; N151-A397 WeakPolarHBondContact O-CA 3.49Å; N151-A397 WeakPolarHBondContact O-CB 3.45Å; N151-A397 PolarHBondContact O-N 3.48Å
152V98.7Very high95.5Very high0 Ų018.4 Ų18.40%012%0.12CC..EExtended strand (participates in β ladder)trans-107.6-14.9-167.9-68.90000114.1F150 F168 I170 Y189 L192 G212 F213 L227F150-V152 HydrophobicContact CB-CG1 3.91Å; F150-V152 WeakPolarHBondContact O-CG1 3.39Å; F150-V152 PolarHBondContact O-N 2.81Å; F150-V152 VanDerWaalsContact O-N 3.12Å; V152-F168 VanDerWaalsContact CG2-O 3.31Å; V152-F168 WeakPolarHBondContact CG2-O 3.12Å; V152-F168 PolarHBondContact N-O 2.83Å; V152-I170 HydrophobicContact CG1-CD1 3.98Å; V152-I170 HydrophobicContact CG1-CG1 3.93Å; V152-I170 HydrophobicContact CG2-CG1 4.21Å; V152-I170 HydrophobicContact CG2-CG2 3.95Å; V152-Y189 HydrophobicContact CB-CD2 4.01Å; V152-Y189 HydrophobicContact CG1-CD2 3.72Å; V152-Y189 HydrophobicContact CG1-CG 4.47Å; V152-L192 HydrophobicContact CB-CD2 3.81Å; V152-L192 HydrophobicContact CG2-CD2 3.92Å; V152-G212 CarbonylContact O-C 3.57Å; V152-G212 WeakPolarHBondContact O-CA 3.47Å; V152-F213 PolarHBondContact O-N 3.1Å; V152-L227 HydrophobicContact CG2-CD1 4.34Å; V152-L227 HydrophobicContact CG2-CD2 3.46Å; V152-L227 VanDerWaalsContact CG2-CD2 3.46Å
153I98.6Very high95.6Very high0 Ų013.8 Ų13.80%010%0.098CC..EExtended strand (participates in β ladder)trans-129.3126.5165.7-55.9174.3000108.1N151 L163 F168 L192 F213 P215 L226 L227N151-I153 PolarHBondContact OD1-O 2.94Å; N151-I153 VanDerWaalsContact OD1-O 3.1Å; I153-L163 HydrophobicContact CG2-CD2 3.99Å; I153-F168 HydrophobicContact CB-CB 4.07Å; I153-F168 HydrophobicContact CB-CD2 4.3Å; I153-F168 HydrophobicContact CB-CG 4.44Å; I153-F168 HydrophobicContact CG2-CD2 4.36Å; I153-F168 PolarHBondContact N-O 2.82Å; I153-F168 PolarHBondContact O-N 3.26Å; I153-L192 HydrophobicContact CD1-CD1 4.27Å; I153-L192 HydrophobicContact CD1-CD2 4.32Å; I153-L192 HydrophobicContact CG1-CD2 3.8Å; I153-F213 CarbonylContact C-O 3.56Å; I153-F213 WeakPolarHBondContact CA-O 3.49Å; I153-P215 HydrophobicContact CG2-CG 4.11Å; I153-L226 HydrophobicContact CD1-CB 4.09Å; I153-L226 HydrophobicContact CD1-CD1 4.31Å; I153-L227 HydrophobicContact CD1-CD2 3.7Å; I153-L227 HydrophobicContact CD1-CG 4.03Å; I153-L227 HydrophobicContact CG1-CD2 3.99Å
154N96.2Very high95.5Very high0 Ų013.1 Ų13.10%09%0.094CC..EExtended strand (participates in β ladder)trans-100133.4176.2-70.9126.1000111.2N151 H158 A159 N161 G212 F213N151-N154 PolarHBondContact ND2-ND2 2.84Å; N151-N154 PolarHBondContact OD1-ND2 3.5Å; N154-H158 HydrophobicContact CB-CB 4.39Å; N154-A159 HydrophobicContact CB-CB 3.95Å; N154-A159 WeakPolarHBondContact O-CB 3.35Å; N154-N161 PolarHBondContact O-ND2 3.2Å; N154-G212 WeakPolarHBondContact OD1-CA 3.46Å; N154-G212 PolarHBondContact OD1-N 3.39Å; N154-G212 PolarHBondContact OD1-O 2.64Å; N154-G212 VanDerWaalsContact OD1-O 3.14Å; N154-F213 PolarHBondContact N-O 3.06Å
155G95.3Very high95.5Very high0 Ų012.8 Ų12.80%09%0.092CC..  trans-130.3-148.2167.600000110.5S157 H158 A159 M165 Q166G155-S157 PolarHBondContact O-N 2.94Å; G155-H158 PolarHBondContact O-N 2.97Å; G155-H158 VanDerWaalsContact O-N 3.09Å; G155-A159 PolarHBondContact O-N 2.92Å; G155-M165 CarbonylContact C-O 3.6Å; G155-M165 VanDerWaalsContact CA-O 3.23Å; G155-M165 WeakPolarHBondContact CA-O 3.44Å; G155-Q166 PolarHBondContact N-O 3.26Å
156G94.1Very high95.4Very high3 Ų312.9 Ų12.93%0.0319%0.093CC..G310 helixtrans50.5-137.3176.600000112.8H158 L163 A164 M165 K262G156-H158 VanDerWaalsContact C-N 3.26Å; G156-H158 PolarHBondContact O-N 3.29Å; G156-L163 PolarHBondContact N-O 2.81Å; G156-A164 WeakPolarHBondContact CA-O 3.28Å; G156-A164 PolarHBondContact N-O 2.77Å; G156-M165 PolarHBondContact N-O 3.02Å; G156-K262 WeakPolarHBondContact O-CD 3.46Å; G156-K262 PolarHBondContact O-NZ 3.21Å
157S90.9Very high95.4Very high50 Ų5013 Ų1335%0.359%0.094SC..G310 helixtrans-78-5.1178.8-64.20000113.7G155 E250G155-S157 PolarHBondContact O-N 2.94Å; S157-E250 PolarHBondContact OG-OE2 2.71Å
158H86.3Confident95.4Very high8 Ų813 Ų134%0.0379%0.094CC..G310 helixtrans-93.4-5.5-178.7-66.8175.4000113.9N154 G155 G156 Q166 E167 D209 E210 S373N154-H158 HydrophobicContact CB-CB 4.39Å; G155-H158 PolarHBondContact O-N 2.97Å; G155-H158 VanDerWaalsContact O-N 3.09Å; G156-H158 VanDerWaalsContact C-N 3.26Å; G156-H158 PolarHBondContact O-N 3.29Å; H158-Q166 HydrophobicContact CB-CG 4.38Å; H158-Q166 PolarHBondContact CE1-NE2 2.93Å; H158-Q166 WeakPolarHBondContact ND1-CG 3.45Å; H158-E167 IonicContact CE1-OE1 3.68Å; H158-E167 IonicContact ND1-OE1 3.3Å; H158-D209 PolarHBondContact O-N 3.08Å; H158-E210 IonicContact CE1-OE1 3.68Å; H158-E210 PolarHBondContact CE1-OE1 3.37Å; H158-E210 VanDerWaalsContact CE1-OE1 3.3Å; H158-E210 IonicContact ND1-OE1 2.78Å; H158-S373 WeakPolarHBondContact NE2-CB 3.32Å
159A88.3Confident95.3Very high13 Ų1313.1 Ų13.111%0.1079%0.094CC..SBendtrans-149.1141.7-17600000113.9N154 G155 N161 A214 K262N154-A159 HydrophobicContact CB-CB 3.95Å; N154-A159 WeakPolarHBondContact O-CB 3.35Å; G155-A159 PolarHBondContact O-N 2.92Å; A159-N161 PolarHBondContact O-N 2.98Å; A159-A214 HydrophobicContact CB-CB 3.75Å; A159-K262 PolarHBondContact O-NZ 2.83Å
160G88.6Confident95.3Very high93 Ų9313.1 Ų13.196%0.9599%0.094SC*.SBendtrans-77.742.6174.700000114.6
161N91.4Very high95.3Very high10 Ų1013.1 Ų13.15%0.0539%0.094CC..SBendtrans-114.1-174.5173.959.415.9000110.9N154 A159 P215 K262N154-N161 PolarHBondContact O-ND2 3.2Å; A159-N161 PolarHBondContact O-N 2.98Å; N161-P215 VanDerWaalsContact CB-O 3.24Å; N161-P215 WeakPolarHBondContact CB-O 3.15Å; N161-P215 PolarHBondContact ND2-O 3.21Å; N161-K262 VanDerWaalsContact O-CD 3.3Å; N161-K262 WeakPolarHBondContact O-CD 3.46Å; N161-K262 WeakPolarHBondContact O-CE 3.48Å; N161-K262 PolarHBondContact O-NZ 3.05Å; N161-K262 PolarHBondContact OD1-NZ 2.76Å
162K93.8Very high95.4Very high89 Ų8913.1 Ų13.139%0.3879%0.094SC..SBendtrans-88.3-21.2176.4-69.9-162.9170.8-150.20115A164 I217 L218 S263K162-A164 PolarHBondContact O-N 2.83Å; K162-I217 CarbonylContact C-O 3.55Å; K162-L218 HydrophobicContact CB-CB 4.08Å; K162-L218 HydrophobicContact CB-CD1 3.86Å; K162-L218 HydrophobicContact CD-CD1 4.46Å; K162-S263 PolarHBondContact NZ-OG 2.94Å
163L95.7Very high95.4Very high0 Ų013.5 Ų13.50%010%0.096CC..  trans-51118.5-177.3-171.462.5000111.5I153 G156 F168 I217 N220 K262I153-L163 HydrophobicContact CG2-CD2 3.99Å; G156-L163 PolarHBondContact N-O 2.81Å; L163-F168 HydrophobicContact CD1-CE2 4.07Å; L163-F168 HydrophobicContact CD1-CZ 3.98Å; L163-F168 HydrophobicContact CD2-CD2 4.07Å; L163-F168 HydrophobicContact CD2-CE2 3.45Å; L163-F168 VanDerWaalsContact CD2-CE2 3.45Å; L163-F168 HydrophobicContact CD2-CZ 4.15Å; L163-F168 HydrophobicContact CG-CE2 3.89Å; L163-F168 HydrophobicContact CG-CZ 4.31Å; L163-I217 WeakPolarHBondContact CA-O 3.47Å; L163-I217 HydrophobicContact CB-CG1 4.31Å; L163-I217 WeakPolarHBondContact CB-O 3.43Å; L163-I217 HydrophobicContact CD1-CD1 4.17Å; L163-I217 HydrophobicContact CD1-CG1 4.13Å; L163-I217 HydrophobicContact CD2-CD1 4.05Å; L163-I217 HydrophobicContact CD2-CG1 4.11Å; L163-I217 HydrophobicContact CG-CG1 4.44Å; L163-I217 PolarHBondContact N-O 2.84Å; L163-N220 HydrophobicContact CD1-CB 4.38Å; L163-N220 VanDerWaalsContact CD1-OD1 3.25Å; L163-N220 WeakPolarHBondContact CD1-OD1 3.46Å; L163-K262 WeakPolarHBondContact O-CE 3.4Å; L163-K262 PolarHBondContact O-NZ 2.78Å
164A96.5Very high95.4Very high1 Ų114 Ų141%0.00810%0.102CC..  trans-76.8-42.8-174.900000113.4G156 K162 F251 L259 F261G156-A164 WeakPolarHBondContact CA-O 3.28Å; G156-A164 PolarHBondContact N-O 2.77Å; K162-A164 PolarHBondContact O-N 2.83Å; A164-F251 HydrophobicContact CB-CD1 4.35Å; A164-F251 HydrophobicContact CB-CE1 4.42Å; A164-L259 HydrophobicContact CB-CB 4.42Å; A164-L259 HydrophobicContact CB-CD2 4.43Å; A164-L259 VanDerWaalsContact CB-O 3.23Å; A164-L259 WeakPolarHBondContact CB-O 3.35Å; A164-F261 HydrophobicContact CB-CD1 4.04Å; A164-F261 HydrophobicContact CB-CE1 4.16Å
165M98.1Very high95.5Very high0 Ų014.5 Ų14.50%011%0.105CC..SBendtrans-69.4139.3179.4-62.7177.7-17300110.6G155 G156 F168 N220 M244 V246 L259 L276 L279 Y280 F283G155-M165 CarbonylContact C-O 3.6Å; G155-M165 VanDerWaalsContact CA-O 3.23Å; G155-M165 WeakPolarHBondContact CA-O 3.44Å; G156-M165 PolarHBondContact N-O 3.02Å; M165-F168 HydrophobicContact CB-CE2 3.94Å; M165-F168 HydrophobicContact CB-CZ 3.89Å; M165-N220 VanDerWaalsContact CB-OD1 3.31Å; M165-N220 WeakPolarHBondContact CB-OD1 3.36Å; M165-N220 HydrophobicContact CE-CB 4.04Å; M165-N220 HydrophobicContact CG-CB 4.32Å; M165-N220 WeakPolarHBondContact CG-OD1 3.27Å; M165-N220 PolarHBondContact N-OD1 3.36Å; M165-N220 HydrophobicContact SD-CB 3.63Å; M165-M244 HydrophobicContact SD-CE 3.32Å; M165-M244 WeakPolarHBondContact SD-CE 3.3Å; M165-V246 HydrophobicContact CE-CG1 4.31Å; M165-V246 HydrophobicContact CG-CB 4.38Å; M165-V246 HydrophobicContact CG-CG1 3.74Å; M165-V246 HydrophobicContact CG-CG2 4.43Å; M165-V246 HydrophobicContact SD-CG1 4.34Å; M165-V246 HydrophobicContact SD-CG2 4.28Å; M165-L259 HydrophobicContact CE-CD2 4.5Å; M165-L276 HydrophobicContact CE-CD1 4.45Å; M165-L279 HydrophobicContact CE-CD2 4.21Å; M165-Y280 HydrophobicContact CE-CD1 4.29Å; M165-Y280 HydrophobicContact CE-CE1 3.55Å; M165-Y280 HydrophobicContact SD-CE1 4.39Å; M165-F283 HydrophobicContact CE-CE2 3.88Å; M165-F283 HydrophobicContact SD-CE2 4.03Å
166Q97.3Very high95.7Very high2 Ų218.1 Ų18.11%0.00914%0.135CC..  trans-79.5-42.1-163.8-172.6162.6-96.900113.8S40 G155 H158 D245 A247S40-Q166 PolarHBondContact OG-NE2 3.06Å; G155-Q166 PolarHBondContact N-O 3.26Å; H158-Q166 HydrophobicContact CB-CG 4.38Å; H158-Q166 PolarHBondContact CE1-NE2 2.93Å; H158-Q166 WeakPolarHBondContact ND1-CG 3.45Å; Q166-D245 PolarHBondContact N-O 3.03Å; Q166-D245 PolarHBondContact NE2-OD2 2.97Å; Q166-A247 HydrophobicContact CB-CB 3.81Å; Q166-A247 HydrophobicContact CG-CB 4.39Å
167E98.4Very high95.9Very high4 Ų421 Ų212%0.01915%0.15CC..EExtended strand (participates in β ladder)trans-137.8132-171.4-43.8-177.5163.800111.4N151 H158 M169 M244 D245 K394N151-E167 VanDerWaalsContact ND2-CG 3.28Å; N151-E167 WeakPolarHBondContact ND2-CG 3.26Å; N151-E167 WeakPolarHBondContact OD1-CA 3.13Å; N151-E167 WeakPolarHBondContact OD1-CB 3.35Å; H158-E167 IonicContact CE1-OE1 3.68Å; H158-E167 IonicContact ND1-OE1 3.3Å; E167-M169 HydrophobicContact CB-CE 4.36Å; E167-M169 HydrophobicContact CB-CG 4.35Å; E167-M244 WeakPolarHBondContact O-CA 3.3Å; E167-D245 HydrophobicContact CB-CB 3.81Å; E167-D245 HydrophobicContact CG-CB 3.72Å; E167-D245 PolarHBondContact N-O 3.32Å; E167-D245 PolarHBondContact O-N 2.81Å; E167-D245 WeakPolarHBondContact OE2-CB 3.16Å; E167-K394 IonicContact OE1-NZ 3.89Å; E167-K394 IonicContact OE2-NZ 2.67Å; E167-K394 PolarHBondContact OE2-NZ 2.95Å
168F98.8Very high96.3Very high0 Ų018.6 Ų18.60%013%0.133CC..EExtended strand (participates in β ladder)trans-117.3110.2168-59.7-109.8000107.8V152 I153 L163 M165 N220 L224 L227 M244V152-F168 VanDerWaalsContact CG2-O 3.31Å; V152-F168 WeakPolarHBondContact CG2-O 3.12Å; V152-F168 PolarHBondContact N-O 2.83Å; I153-F168 HydrophobicContact CB-CB 4.07Å; I153-F168 HydrophobicContact CB-CD2 4.3Å; I153-F168 HydrophobicContact CB-CG 4.44Å; I153-F168 HydrophobicContact CG2-CD2 4.36Å; I153-F168 PolarHBondContact N-O 2.82Å; I153-F168 PolarHBondContact O-N 3.26Å; L163-F168 HydrophobicContact CD1-CE2 4.07Å; L163-F168 HydrophobicContact CD1-CZ 3.98Å; L163-F168 HydrophobicContact CD2-CD2 4.07Å; L163-F168 HydrophobicContact CD2-CE2 3.45Å; L163-F168 VanDerWaalsContact CD2-CE2 3.45Å; L163-F168 HydrophobicContact CD2-CZ 4.15Å; L163-F168 HydrophobicContact CG-CE2 3.89Å; L163-F168 HydrophobicContact CG-CZ 4.31Å; M165-F168 HydrophobicContact CB-CE2 3.94Å; M165-F168 HydrophobicContact CB-CZ 3.89Å; F168-N220 HydrophobicContact CE1-CB 4.43Å; F168-N220 WeakPolarHBondContact CE1-O 3.47Å; F168-N220 HydrophobicContact CZ-CB 4.03Å; F168-L224 HydrophobicContact CD1-CD2 3.94Å; F168-L224 HydrophobicContact CD1-CG 4.18Å; F168-L224 HydrophobicContact CE1-CD2 4.29Å; F168-L224 HydrophobicContact CE1-CG 4.09Å; F168-L227 HydrophobicContact CB-CD1 3.77Å; F168-M244 HydrophobicContact CD1-CE 4.19Å; F168-M244 HydrophobicContact CE1-CE 3.69Å; F168-M244 HydrophobicContact CZ-CE 4.2Å
169M98.9Very high96.9Very high1 Ų126.9 Ų26.91%0.00516%0.164CC..EExtended strand (participates in β ladder)trans-105.9147-170.1-65.4176.3-9000112.2A149 F150 N151 E167 L171 I242 G243 D245 K394A149-M169 HydrophobicContact CB-CB 4.41Å; A149-M169 HydrophobicContact CB-SD 3.76Å; F150-M169 CarbonylContact O-C 3.55Å; F150-M169 WeakPolarHBondContact O-CA 3.43Å; N151-M169 HydrophobicContact CB-CG 4.09Å; E167-M169 HydrophobicContact CB-CE 4.36Å; E167-M169 HydrophobicContact CB-CG 4.35Å; M169-L171 HydrophobicContact CB-CD1 4.2Å; M169-I242 VanDerWaalsContact O-CA 3.31Å; M169-I242 WeakPolarHBondContact O-CA 3.19Å; M169-I242 WeakPolarHBondContact O-CG2 3.34Å; M169-G243 WeakPolarHBondContact CA-O 3.29Å; M169-G243 WeakPolarHBondContact CB-O 3.34Å; M169-G243 PolarHBondContact N-O 3.36Å; M169-G243 PolarHBondContact O-N 2.88Å; M169-D245 HydrophobicContact CE-CB 4.14Å; M169-K394 HydrophobicContact CE-CD 4.5Å; M169-K394 HydrophobicContact SD-CB 4.13Å; M169-K394 HydrophobicContact SD-CD 4.17Å
170I98.9Very high97.4Very high0 Ų027.9 Ų27.90%017%0.167CC..EExtended strand (participates in β ladder)trans-108.9137.9166.460.1172.7000110.3F150 V152 V188 L227 I231 V240F150-I170 HydrophobicContact CB-CG1 3.86Å; F150-I170 HydrophobicContact CD2-CG1 4.13Å; F150-I170 HydrophobicContact CG-CG1 4.49Å; F150-I170 PolarHBondContact N-O 2.92Å; F150-I170 PolarHBondContact O-N 3.07Å; V152-I170 HydrophobicContact CG1-CD1 3.98Å; V152-I170 HydrophobicContact CG1-CG1 3.93Å; V152-I170 HydrophobicContact CG2-CG1 4.21Å; V152-I170 HydrophobicContact CG2-CG2 3.95Å; I170-V188 HydrophobicContact CD1-CB 3.62Å; I170-V188 HydrophobicContact CD1-CG1 3.51Å; I170-V188 HydrophobicContact CD1-CG2 4.43Å; I170-V188 HydrophobicContact CG2-CG1 4.4Å; I170-L227 HydrophobicContact CG2-CD1 4.13Å; I170-L227 HydrophobicContact CG2-CD2 4.36Å; I170-I231 HydrophobicContact CG2-CD1 4.16Å; I170-I231 HydrophobicContact CG2-CG1 4.49Å; I170-V240 HydrophobicContact CB-CG1 3.72Å; I170-V240 HydrophobicContact CG2-CG1 4.11Å
171L98.9Very high97.9Very high1 Ų123.5 Ų23.51%0.00512%0.121CC..EExtended strand (participates in β ladder)trans-123.8107.4-179.4-69.584.3000109.3V147 A149 M169 V173 V240 V241 G243 F428V147-L171 HydrophobicContact CG1-CB 3.99Å; V147-L171 HydrophobicContact CG1-CD2 4.45Å; A149-L171 HydrophobicContact CB-CD1 4.06Å; A149-L171 HydrophobicContact CB-CD2 4.13Å; A149-L171 HydrophobicContact CB-CG 3.82Å; M169-L171 HydrophobicContact CB-CD1 4.2Å; L171-V173 HydrophobicContact CB-CG1 4.09Å; L171-V173 PolarHBondContact O-N 3.36Å; L171-V240 WeakPolarHBondContact O-CA 3.35Å; L171-V241 HydrophobicContact CB-CG2 3.8Å; L171-V241 PolarHBondContact N-O 2.97Å; L171-V241 PolarHBondContact O-N 3.26Å; L171-G243 VanDerWaalsContact CD1-N 3.3Å; L171-F428 HydrophobicContact CD2-CE2 4.37Å
172P98.9Very high98.2Very high0 Ų023.9 Ų23.90%012%0.123CC..  trans-75.157.6177.9-19.134.9000113.8P148 F150 G174 A175 A181 I184 K239 V240P148-P172 WeakPolarHBondContact O-CD 3.5Å; F150-P172 HydrophobicContact CD2-CG 4.28Å; F150-P172 HydrophobicContact CE2-CG 3.9Å; P172-G174 PolarHBondContact O-N 3.26Å; P172-G174 VanDerWaalsContact O-N 3.11Å; P172-A175 HydrophobicContact CB-CB 4.47Å; P172-A175 WeakPolarHBondContact O-CB 3.32Å; P172-A175 PolarHBondContact O-N 3.34Å; P172-A175 VanDerWaalsContact O-N 3.1Å; P172-A181 HydrophobicContact CB-CB 4Å; P172-A181 HydrophobicContact CG-CB 4.41Å; P172-A181 WeakPolarHBondContact CG-O 3.38Å; P172-I184 HydrophobicContact CB-CB 4.12Å; P172-I184 HydrophobicContact CB-CG2 3.88Å; P172-I184 HydrophobicContact CG-CB 4.36Å; P172-I184 HydrophobicContact CG-CG2 4.07Å; P172-K239 CarbonylContact C-O 3.21Å; P172-K239 WeakPolarHBondContact CA-O 3.44Å; P172-V240 HydrophobicContact CB-CG2 4.4Å
173V98.9Very high98.5Very high9 Ų925.1 Ų25.16%0.05513%0.125CC..THydrogen-bonded Turntrans-60.9-21.1-176.4-630000113.9V147 L171 K239 V241 G425 R426 F428V147-V173 HydrophobicContact CG1-CG1 4.01Å; V147-V173 HydrophobicContact CG2-CG1 4.39Å; L171-V173 HydrophobicContact CB-CG1 4.09Å; L171-V173 PolarHBondContact O-N 3.36Å; V173-K239 PolarHBondContact N-O 2.73Å; V173-K239 VanDerWaalsContact N-O 3.16Å; V173-V241 HydrophobicContact CB-CG2 4.37Å; V173-V241 HydrophobicContact CG1-CG2 3.67Å; V173-V241 HydrophobicContact CG2-CB 4.45Å; V173-V241 HydrophobicContact CG2-CG1 3.9Å; V173-V241 HydrophobicContact CG2-CG2 3.74Å; V173-G425 CarbonylContact O-C 3.53Å; V173-G425 VanDerWaalsContact O-CA 3.26Å; V173-G425 WeakPolarHBondContact O-CA 3.21Å; V173-R426 HydrophobicContact CB-CG 4.29Å; V173-R426 HydrophobicContact CG2-CG 4.3Å; V173-R426 PolarHBondContact O-N 3.47Å; V173-R426 VanDerWaalsContact O-N 3.16Å; V173-F428 HydrophobicContact CG1-CD1 3.88Å; V173-F428 HydrophobicContact CG1-CE1 4.17Å
174G98.8Very high98.6Very high11 Ų1125.1 Ų25.111%0.11313%0.125CC..THydrogen-bonded Turntrans-91.85.4178.200000115.4P172 K239P172-G174 PolarHBondContact O-N 3.26Å; P172-G174 VanDerWaalsContact O-N 3.11Å; G174-K239 PolarHBondContact N-O 2.82Å
175A98.8Very high98.7Very high9 Ų925.1 Ų25.17%0.07413%0.125CC..  trans-68.8151170.600000111.4P172 E180 A181 I184 F423P172-A175 HydrophobicContact CB-CB 4.47Å; P172-A175 WeakPolarHBondContact O-CB 3.32Å; P172-A175 PolarHBondContact O-N 3.34Å; P172-A175 VanDerWaalsContact O-N 3.1Å; A175-E180 HydrophobicContact CB-CB 4.14Å; A175-E180 HydrophobicContact CB-CG 4.22Å; A175-A181 HydrophobicContact CB-CB 3.74Å; A175-I184 HydrophobicContact CB-CD1 4.13Å; A175-F423 HydrophobicContact CB-CE1 3.92Å; A175-F423 HydrophobicContact CB-CZ 4.25Å; A175-F423 WeakPolarHBondContact O-CD1 3.18Å; A175-F423 VanDerWaalsContact O-CE1 3.27Å; A175-F423 WeakPolarHBondContact O-CE1 3.48Å
176A98.4Very high98.8Very high76 Ų7626.4 Ų26.463%0.62814%0.136SC*.SBendtrans-79.8-26.1177.600000112.9E180A176-E180 VanDerWaalsContact CB-OE2 3.28Å; A176-E180 WeakPolarHBondContact CB-OE2 3.26Å; A176-E180 PolarHBondContact N-OE2 3.24Å
177N98.8Very high98.8Very high64 Ų6429.4 Ų29.434%0.34215%0.15SC..SBendtrans-155.8171.7-177.658.550.1000110.6R179 E180 A181 E414N177-R179 PolarHBondContact OD1-N 2.88Å; N177-E180 PolarHBondContact O-N 2.99Å; N177-E180 WeakPolarHBondContact OD1-CB 3.44Å; N177-E180 PolarHBondContact OD1-N 3.36Å; N177-A181 PolarHBondContact O-N 2.94Å; N177-E414 WeakPolarHBondContact CB-OE1 3.46Å
178F98.9Very high98.9Very high0 Ų029.2 Ų29.20%015%0.149CC..Hα-helixtrans-65.8-39.8-176.5-176.2-94.4000111.8L145 P146 P148 E180 A181 M182 Y407 L410 L411 E414 F423L145-F178 HydrophobicContact CB-CB 4.29Å; L145-F178 HydrophobicContact CD1-CB 4.03Å; L145-F178 HydrophobicContact CD2-CB 4.49Å; P146-F178 HydrophobicContact CG-CE2 4.47Å; P146-F178 VanDerWaalsContact O-CD2 3.31Å; P146-F178 WeakPolarHBondContact O-CD2 3.35Å; P148-F178 HydrophobicContact CB-CE2 4.15Å; P148-F178 HydrophobicContact CG-CE2 3.96Å; F178-E180 VanDerWaalsContact C-N 3.34Å; F178-E180 PolarHBondContact O-N 3Å; F178-A181 WeakPolarHBondContact O-CB 3.37Å; F178-A181 PolarHBondContact O-N 2.88Å; F178-A181 VanDerWaalsContact O-N 3.11Å; F178-M182 HydrophobicContact CD1-CG 3.94Å; F178-M182 HydrophobicContact CE1-CG 3.34Å; F178-M182 HydrophobicContact CE1-SD 3.93Å; F178-M182 HydrophobicContact CZ-CG 3.69Å; F178-M182 HydrophobicContact CZ-SD 3.71Å; F178-M182 PolarHBondContact O-N 2.81Å; F178-Y407 WeakPolarHBondContact CE1-O 3.48Å; F178-Y407 HydrophobicContact CZ-CD1 4.08Å; F178-L410 HydrophobicContact CD1-CB 3.81Å; F178-L410 HydrophobicContact CD2-CB 4.44Å; F178-L410 HydrophobicContact CE1-CB 3.25Å; F178-L410 HydrophobicContact CE1-CD1 4.27Å; F178-L410 HydrophobicContact CE1-CG 4.38Å; F178-L410 HydrophobicContact CE2-CB 3.95Å; F178-L410 HydrophobicContact CE2-CD1 3.61Å; F178-L410 HydrophobicContact CE2-CG 4.35Å; F178-L410 HydrophobicContact CG-CB 4.39Å; F178-L410 HydrophobicContact CZ-CB 3.34Å; F178-L410 HydrophobicContact CZ-CD1 3.44Å; F178-L410 VanDerWaalsContact CZ-CD1 3.44Å; F178-L410 HydrophobicContact CZ-CG 4.01Å; F178-L411 HydrophobicContact CD1-CD2 3.91Å; F178-L411 HydrophobicContact CD1-CG 4.21Å; F178-L411 HydrophobicContact CE1-CD2 4.15Å; F178-L411 HydrophobicContact CE1-CG 4.03Å; F178-E414 WeakPolarHBondContact CA-OE1 3.49Å; F178-E414 VanDerWaalsContact CB-OE1 3.27Å; F178-E414 WeakPolarHBondContact CB-OE1 3.42Å; F178-E414 PolarHBondContact N-OE1 3.44Å; F178-F423 HydrophobicContact CB-CD2 4.15Å; F178-F423 HydrophobicContact CB-CE2 4.39Å; F178-F423 HydrophobicContact CD2-CE2 4.35Å
179R98.9Very high98.9Very high181 Ų18129.7 Ų29.768%0.68315%0.151SC*.Hα-helixtrans-57.5-43.1174.3179.4178178.9-179.71.1112.9N177 R183 L411 E414N177-R179 PolarHBondContact OD1-N 2.88Å; R179-R183 PolarHBondContact O-N 3.41Å; R179-R183 VanDerWaalsContact O-N 3.13Å; R179-L411 HydrophobicContact CB-CD2 3.85Å; R179-L411 HydrophobicContact CG-CD2 4.17Å; R179-E414 WeakPolarHBondContact CB-OE2 3.5Å; R179-E414 PolarHBondContact N-OE2 2.98Å
180E98.9Very high98.9Very high35 Ų3534.8 Ų34.816%0.16417%0.174CC..Hα-helixtrans-67.2-40.7174.4-171.7-172.3-175.600110.9A175 A176 N177 F178 M182 R183 I184 K239A175-E180 HydrophobicContact CB-CB 4.14Å; A175-E180 HydrophobicContact CB-CG 4.22Å; A176-E180 VanDerWaalsContact CB-OE2 3.28Å; A176-E180 WeakPolarHBondContact CB-OE2 3.26Å; A176-E180 PolarHBondContact N-OE2 3.24Å; N177-E180 PolarHBondContact O-N 2.99Å; N177-E180 WeakPolarHBondContact OD1-CB 3.44Å; N177-E180 PolarHBondContact OD1-N 3.36Å; F178-E180 VanDerWaalsContact C-N 3.34Å; F178-E180 PolarHBondContact O-N 3Å; E180-M182 VanDerWaalsContact C-N 3.33Å; E180-M182 PolarHBondContact O-N 2.99Å; E180-R183 PolarHBondContact O-N 3.27Å; E180-I184 HydrophobicContact CG-CD1 3.9Å; E180-I184 HydrophobicContact CG-CG1 4.28Å; E180-I184 WeakPolarHBondContact O-CG1 3.39Å; E180-I184 PolarHBondContact O-N 2.73Å; E180-K239 IonicContact OE1-NZ 3.72Å; E180-K239 PolarHBondContact OE1-NZ 2.89Å
181A98.9Very high98.9Very high0 Ų036.9 Ų36.90%019%0.185CC..Hα-helixtrans-59-43.5176.100000111.9P148 P172 A175 N177 F178 R183 I184 G185 F423P148-A181 HydrophobicContact CG-CB 4.03Å; P172-A181 HydrophobicContact CB-CB 4Å; P172-A181 HydrophobicContact CG-CB 4.41Å; P172-A181 WeakPolarHBondContact CG-O 3.38Å; A175-A181 HydrophobicContact CB-CB 3.74Å; N177-A181 PolarHBondContact O-N 2.94Å; F178-A181 WeakPolarHBondContact O-CB 3.37Å; F178-A181 PolarHBondContact O-N 2.88Å; F178-A181 VanDerWaalsContact O-N 3.11Å; A181-R183 PolarHBondContact O-N 3.38Å; A181-I184 PolarHBondContact O-N 3.24Å; A181-G185 PolarHBondContact O-N 3.42Å; A181-F423 HydrophobicContact CB-CE2 4.1Å; A181-F423 HydrophobicContact CB-CZ 3.77Å
182M98.9Very high98.9Very high18 Ų1836.8 Ų36.89%0.08919%0.185CC..Hα-helixtrans-59.5-45.2173.8-78.3-57.4-52.300112.5F150 F178 E180 G185 A186 Y407 L411F150-M182 HydrophobicContact CE1-CE 4.02Å; F150-M182 HydrophobicContact CE1-SD 3.64Å; F150-M182 HydrophobicContact CZ-CE 4.18Å; F150-M182 HydrophobicContact CZ-SD 3.46Å; F150-M182 WeakPolarHBondContact CZ-SD 3.34Å; F178-M182 HydrophobicContact CD1-CG 3.94Å; F178-M182 HydrophobicContact CE1-CG 3.34Å; F178-M182 HydrophobicContact CE1-SD 3.93Å; F178-M182 HydrophobicContact CZ-CG 3.69Å; F178-M182 HydrophobicContact CZ-SD 3.71Å; F178-M182 PolarHBondContact O-N 2.81Å; E180-M182 VanDerWaalsContact C-N 3.33Å; E180-M182 PolarHBondContact O-N 2.99Å; M182-G185 PolarHBondContact O-N 3.37Å; M182-A186 WeakPolarHBondContact O-CB 3.38Å; M182-A186 PolarHBondContact O-N 3.18Å; M182-Y407 HydrophobicContact CE-CD2 4.3Å; M182-Y407 HydrophobicContact CE-CG 3.92Å; M182-Y407 HydrophobicContact SD-CD1 3.72Å; M182-Y407 HydrophobicContact SD-CD2 4.48Å; M182-Y407 HydrophobicContact SD-CG 3.69Å; M182-L411 HydrophobicContact CB-CD2 4.4Å; M182-L411 HydrophobicContact CG-CD2 4.1Å; M182-L411 HydrophobicContact CG-CG 4.31Å
183R98.9Very high98.9Very high116 Ų11641.1 Ų41.144%0.43820%0.204SC..Hα-helixtrans-61.9-49.4177.6-178.1-179.871.393.5-0.5111.5R179 E180 A181 G185 A186 E187 Y236R179-R183 PolarHBondContact O-N 3.41Å; R179-R183 VanDerWaalsContact O-N 3.13Å; E180-R183 PolarHBondContact O-N 3.27Å; A181-R183 PolarHBondContact O-N 3.38Å; R183-G185 PolarHBondContact O-N 2.85Å; R183-A186 PolarHBondContact O-N 2.92Å; R183-E187 WeakPolarHBondContact CD-OE1 3.17Å; R183-E187 HydrophobicContact CG-CG 4.41Å; R183-E187 WeakPolarHBondContact CG-OE1 3.36Å; R183-E187 IonicContact CZ-OE1 3.3Å; R183-E187 IonicContact NE-OE1 2.66Å; R183-E187 IonicContact NH1-OE1 2.73Å; R183-E187 PolarHBondContact NH1-OE1 3.1Å; R183-E187 IonicContact NH1-OE2 3.24Å; R183-E187 WeakPolarHBondContact O-CB 3.36Å; R183-E187 WeakPolarHBondContact O-CG 3.36Å; R183-E187 PolarHBondContact O-N 2.99Å; R183-Y236 PolarHBondContact NH1-OH 3.46Å
184I98.9Very high98.8Very high0 Ų045.1 Ų45.10%023%0.225CC..Hα-helixtrans-58.2-48.9178.3-69.8173.4000110.2P172 A175 E180 A181 A186 E187 V188 Y236 K239 V240P172-I184 HydrophobicContact CB-CB 4.12Å; P172-I184 HydrophobicContact CB-CG2 3.88Å; P172-I184 HydrophobicContact CG-CB 4.36Å; P172-I184 HydrophobicContact CG-CG2 4.07Å; A175-I184 HydrophobicContact CB-CD1 4.13Å; E180-I184 HydrophobicContact CG-CD1 3.9Å; E180-I184 HydrophobicContact CG-CG1 4.28Å; E180-I184 WeakPolarHBondContact O-CG1 3.39Å; E180-I184 PolarHBondContact O-N 2.73Å; A181-I184 PolarHBondContact O-N 3.24Å; I184-A186 PolarHBondContact O-N 3.06Å; I184-E187 PolarHBondContact O-N 2.93Å; I184-V188 HydrophobicContact CG2-CG2 4.4Å; I184-V188 VanDerWaalsContact O-CG2 3.32Å; I184-V188 WeakPolarHBondContact O-CG2 3.28Å; I184-V188 PolarHBondContact O-N 2.97Å; I184-Y236 HydrophobicContact CB-CD2 4.44Å; I184-Y236 HydrophobicContact CB-CE2 4.42Å; I184-Y236 HydrophobicContact CD1-CD1 4.16Å; I184-Y236 HydrophobicContact CD1-CE1 4.15Å; I184-Y236 HydrophobicContact CG1-CD1 4.02Å; I184-Y236 HydrophobicContact CG1-CD2 4.4Å; I184-Y236 HydrophobicContact CG1-CE1 3.75Å; I184-Y236 HydrophobicContact CG1-CE2 4.16Å; I184-Y236 HydrophobicContact CG1-CG 4.34Å; I184-Y236 HydrophobicContact CG2-CD1 4.29Å; I184-Y236 HydrophobicContact CG2-CD2 3.8Å; I184-Y236 HydrophobicContact CG2-CE2 4.27Å; I184-Y236 HydrophobicContact CG2-CG 3.82Å; I184-K239 HydrophobicContact CD1-CB 4.43Å; I184-K239 HydrophobicContact CD1-CD 3.77Å; I184-V240 HydrophobicContact CG2-CG2 3.37Å
185G98.9Very high98.8Very high0 Ų045 Ų450%022%0.222CC..Hα-helixtrans-57.8-45.5178.500000112.8A181 M182 R183 Y189A181-G185 PolarHBondContact O-N 3.42Å; M182-G185 PolarHBondContact O-N 3.37Å; R183-G185 PolarHBondContact O-N 2.85Å; G185-Y189 VanDerWaalsContact O-CB 3.32Å; G185-Y189 WeakPolarHBondContact O-CB 3.37Å; G185-Y189 PolarHBondContact O-N 2.76Å
186A98.9Very high98.8Very high27 Ų2744.6 Ų44.622%0.22322%0.219CC..Hα-helixtrans-66.1-42.7178.100000113M182 R183 I184 Y189 H190 P398M182-A186 WeakPolarHBondContact O-CB 3.38Å; M182-A186 PolarHBondContact O-N 3.18Å; R183-A186 PolarHBondContact O-N 2.92Å; I184-A186 PolarHBondContact O-N 3.06Å; A186-Y189 PolarHBondContact O-N 2.86Å; A186-H190 PolarHBondContact O-N 2.69Å; A186-H190 PolarHBondContact O-ND1 2.91Å; A186-P398 HydrophobicContact CB-CB 4.38Å
187E98.9Very high98.8Very high65 Ų6546.5 Ų46.530%0.30421%0.213SC..Hα-helixtrans-65-40.8177.6-73.4175.6-16100111.8R183 I184 N191 Y236R183-E187 WeakPolarHBondContact CD-OE1 3.17Å; R183-E187 HydrophobicContact CG-CG 4.41Å; R183-E187 WeakPolarHBondContact CG-OE1 3.36Å; R183-E187 IonicContact CZ-OE1 3.3Å; R183-E187 IonicContact NE-OE1 2.66Å; R183-E187 IonicContact NH1-OE1 2.73Å; R183-E187 PolarHBondContact NH1-OE1 3.1Å; R183-E187 IonicContact NH1-OE2 3.24Å; R183-E187 WeakPolarHBondContact O-CB 3.36Å; R183-E187 WeakPolarHBondContact O-CG 3.36Å; R183-E187 PolarHBondContact O-N 2.99Å; I184-E187 PolarHBondContact O-N 2.93Å; E187-N191 PolarHBondContact O-N 3.07Å; E187-N191 PolarHBondContact O-ND2 3.1Å; E187-Y236 HydrophobicContact CB-CE2 4.09Å; E187-Y236 WeakPolarHBondContact OE2-CE2 3.4Å; E187-Y236 VanDerWaalsContact OE2-CZ 3.24Å; E187-Y236 PolarHBondContact OE2-OH 3.18Å
188V98.9Very high98.8Very high0 Ų050.5 Ų50.50%023%0.229CC..Hα-helixtrans-64.8-44173.1175.30000110.8I170 I184 H190 N191 L192 A230 I231 A234 Y236 V240I170-V188 HydrophobicContact CD1-CB 3.62Å; I170-V188 HydrophobicContact CD1-CG1 3.51Å; I170-V188 HydrophobicContact CD1-CG2 4.43Å; I170-V188 HydrophobicContact CG2-CG1 4.4Å; I184-V188 HydrophobicContact CG2-CG2 4.4Å; I184-V188 VanDerWaalsContact O-CG2 3.32Å; I184-V188 WeakPolarHBondContact O-CG2 3.28Å; I184-V188 PolarHBondContact O-N 2.97Å; V188-H190 PolarHBondContact O-N 3.01Å; V188-N191 PolarHBondContact O-N 2.94Å; V188-L192 WeakPolarHBondContact O-CB 3.15Å; V188-L192 PolarHBondContact O-N 2.8Å; V188-A230 HydrophobicContact CG1-CB 4.31Å; V188-I231 HydrophobicContact CG1-CG1 3.81Å; V188-I231 HydrophobicContact CG2-CG1 4.46Å; V188-A234 HydrophobicContact CG2-CB 3.8Å; V188-Y236 HydrophobicContact CG2-CD2 3.98Å; V188-V240 HydrophobicContact CG2-CG2 4.45Å
189Y98.9Very high98.7Very high11 Ų1156 Ų564%0.04325%0.253CS..Hα-helixtrans-60.2-42.4177.5177.8-101.8000112.6V152 G185 A186 L192 K193 V207 G211 F213 A397 P398 C399V152-Y189 HydrophobicContact CB-CD2 4.01Å; V152-Y189 HydrophobicContact CG1-CD2 3.72Å; V152-Y189 HydrophobicContact CG1-CG 4.47Å; G185-Y189 VanDerWaalsContact O-CB 3.32Å; G185-Y189 WeakPolarHBondContact O-CB 3.37Å; G185-Y189 PolarHBondContact O-N 2.76Å; A186-Y189 PolarHBondContact O-N 2.86Å; Y189-L192 WeakPolarHBondContact O-CB 3.04Å; Y189-L192 PolarHBondContact O-N 3.49Å; Y189-K193 PolarHBondContact O-N 2.9Å; Y189-V207 WeakPolarHBondContact OH-CG1 3.42Å; Y189-G211 WeakPolarHBondContact CE2-O 3.32Å; Y189-G211 PolarHBondContact OH-O 2.94Å; Y189-F213 HydrophobicContact CD1-CE2 4.48Å; Y189-F213 HydrophobicContact CD1-CZ 4.33Å; Y189-F213 HydrophobicContact CD2-CD2 4.35Å; Y189-F213 AromaticContact CD2-CE2 3.65Å; Y189-F213 HydrophobicContact CD2-CE2 3.65Å; Y189-F213 HydrophobicContact CD2-CZ 4.16Å; Y189-F213 HydrophobicContact CE1-CE2 4.2Å; Y189-F213 AromaticContact CE1-CZ 3.72Å; Y189-F213 HydrophobicContact CE1-CZ 3.72Å; Y189-F213 AromaticContact CE2-CD2 3.92Å; Y189-F213 HydrophobicContact CE2-CD2 3.92Å; Y189-F213 HydrophobicContact CE2-CE1 4.35Å; Y189-F213 AromaticContact CE2-CE2 3.34Å; Y189-F213 HydrophobicContact CE2-CE2 3.34Å; Y189-F213 AromaticContact CE2-CZ 3.57Å; Y189-F213 HydrophobicContact CE2-CZ 3.57Å; Y189-F213 HydrophobicContact CG-CE2 4.23Å; Y189-F213 AromaticContact CZ-CE1 3.95Å; Y189-F213 AromaticContact CZ-CE2 3.65Å; Y189-F213 AromaticContact CZ-CZ 3.31Å; Y189-F213 WeakPolarHBondContact O-CE2 3.41Å; Y189-F213 WeakPolarHBondContact OH-CZ 3.48Å; Y189-A397 HydrophobicContact CE2-CB 4.09Å; Y189-P398 HydrophobicContact CD1-CG 4.05Å; Y189-P398 HydrophobicContact CD2-CG 4.33Å; Y189-P398 HydrophobicContact CG-CG 3.76Å; Y189-C399 HydrophobicContact CE1-CB 3.97Å; Y189-C399 WeakPolarHBondContact OH-CB 3.36Å
190H98.9Very high98.6Very high108 Ų10850.9 Ų50.950%0.523%0.234SC..Hα-helixtrans-68.1-37.3175.6-66150.6000112.9A186 V188 K193 N194A186-H190 PolarHBondContact O-N 2.69Å; A186-H190 PolarHBondContact O-ND1 2.91Å; V188-H190 PolarHBondContact O-N 3.01Å; H190-K193 WeakPolarHBondContact O-CB 3.32Å; H190-K193 PolarHBondContact O-N 2.88Å; H190-N194 PolarHBondContact O-N 3.39Å; H190-N194 PolarHBondContact O-ND2 3.35Å
191N98.9Very high98.5Very high43 Ų4350.8 Ų50.823%0.2324%0.242CC..Hα-helixtrans-63.9-42.2172.1-86.4-79.5000111.5E187 V188 K193 N194 V195 A234E187-N191 PolarHBondContact O-N 3.07Å; E187-N191 PolarHBondContact O-ND2 3.1Å; V188-N191 PolarHBondContact O-N 2.94Å; N191-K193 VanDerWaalsContact C-N 3.3Å; N191-K193 PolarHBondContact O-N 3.39Å; N191-N194 WeakPolarHBondContact O-CB 3.16Å; N191-N194 PolarHBondContact O-N 2.86Å; N191-N194 VanDerWaalsContact O-N 3.08Å; N191-V195 WeakPolarHBondContact O-CG2 3.36Å; N191-V195 PolarHBondContact O-N 3.26Å; N191-A234 HydrophobicContact CB-CB 4.39Å
192L98.9Very high98.4Very high0 Ų057.5 Ų57.50%027%0.272CS..Hα-helixtrans-58.9-42.5175.8179.863.1000111.5V152 I153 V188 Y189 N194 V195 I196 F213 L226 L227 A230V152-L192 HydrophobicContact CB-CD2 3.81Å; V152-L192 HydrophobicContact CG2-CD2 3.92Å; I153-L192 HydrophobicContact CD1-CD1 4.27Å; I153-L192 HydrophobicContact CD1-CD2 4.32Å; I153-L192 HydrophobicContact CG1-CD2 3.8Å; V188-L192 WeakPolarHBondContact O-CB 3.15Å; V188-L192 PolarHBondContact O-N 2.8Å; Y189-L192 WeakPolarHBondContact O-CB 3.04Å; Y189-L192 PolarHBondContact O-N 3.49Å; L192-N194 VanDerWaalsContact C-N 3.27Å; L192-N194 PolarHBondContact O-N 3.48Å; L192-V195 PolarHBondContact O-N 3.49Å; L192-I196 HydrophobicContact CD1-CD1 3.86Å; L192-I196 HydrophobicContact CD1-CG1 4.07Å; L192-I196 HydrophobicContact CD2-CD1 4.45Å; L192-I196 HydrophobicContact CG-CD1 3.8Å; L192-I196 HydrophobicContact CG-CG1 4.38Å; L192-I196 WeakPolarHBondContact O-CB 3.16Å; L192-I196 WeakPolarHBondContact O-CG1 3.36Å; L192-I196 PolarHBondContact O-N 3.04Å; L192-F213 HydrophobicContact CB-CE2 4.34Å; L192-F213 HydrophobicContact CD2-CD2 3.86Å; L192-F213 HydrophobicContact CD2-CE2 4.29Å; L192-F213 HydrophobicContact CG-CD2 3.91Å; L192-F213 HydrophobicContact CG-CE2 4.22Å; L192-L226 HydrophobicContact CD1-CB 3.96Å; L192-L227 HydrophobicContact CD1-CD2 4.1Å; L192-L227 HydrophobicContact CD2-CD2 3.67Å; L192-A230 HydrophobicContact CB-CB 3.68Å; L192-A230 HydrophobicContact CD1-CB 3.95Å; L192-A230 HydrophobicContact CG-CB 4.41Å
193K98.8Very high98.2Very high90 Ų9062.2 Ų62.239%0.39130%0.297SS..Hα-helixtrans-53.7-45.9173.3-165.2172.1-177.9170.60111.9Y189 H190 N191 K197 T205 F213Y189-K193 PolarHBondContact O-N 2.9Å; H190-K193 WeakPolarHBondContact O-CB 3.32Å; H190-K193 PolarHBondContact O-N 2.88Å; N191-K193 VanDerWaalsContact C-N 3.3Å; N191-K193 PolarHBondContact O-N 3.39Å; K193-K197 VanDerWaalsContact O-CB 3.24Å; K193-K197 WeakPolarHBondContact O-CB 3.4Å; K193-K197 PolarHBondContact O-N 3.17Å; K193-T205 HydrophobicContact CG-CG2 3.98Å; K193-T205 WeakPolarHBondContact O-CG2 3.34Å; K193-F213 HydrophobicContact CB-CE1 4Å; K193-F213 HydrophobicContact CB-CE2 3.77Å; K193-F213 HydrophobicContact CB-CZ 3.33Å; K193-F213 HydrophobicContact CD-CE1 3.93Å; K193-F213 HydrophobicContact CD-CZ 3.84Å; K193-F213 HydrophobicContact CG-CE1 3.65Å; K193-F213 HydrophobicContact CG-CE2 4.36Å; K193-F213 HydrophobicContact CG-CZ 3.52Å
194N98.6Very high98Very high94 Ų9457.3 Ų57.350%0.50328%0.281SS..Hα-helixtrans-68.1-43.1-179.4-67.1-26.9000111.5H190 N191 L192 K197 E198H190-N194 PolarHBondContact O-N 3.39Å; H190-N194 PolarHBondContact O-ND2 3.35Å; N191-N194 WeakPolarHBondContact O-CB 3.16Å; N191-N194 PolarHBondContact O-N 2.86Å; N191-N194 VanDerWaalsContact O-N 3.08Å; L192-N194 VanDerWaalsContact C-N 3.27Å; L192-N194 PolarHBondContact O-N 3.48Å; N194-K197 PolarHBondContact O-N 2.52Å; N194-E198 VanDerWaalsContact O-CB 3.28Å; N194-E198 WeakPolarHBondContact O-CB 3.44Å; N194-E198 PolarHBondContact O-N 3.42Å
195V98.6Very high97.9Very high9 Ų958.2 Ų58.26%0.05529%0.287CS..Hα-helixtrans-59.5-47.6176.11730000111N191 L192 E198 K199 L226 T229 K233N191-V195 WeakPolarHBondContact O-CG2 3.36Å; N191-V195 PolarHBondContact O-N 3.26Å; L192-V195 PolarHBondContact O-N 3.49Å; V195-E198 PolarHBondContact O-N 2.91Å; V195-K199 WeakPolarHBondContact O-CB 3.04Å; V195-K199 PolarHBondContact O-N 2.65Å; V195-L226 HydrophobicContact CG1-CD2 3.69Å; V195-T229 HydrophobicContact CG1-CG2 4.1Å; V195-T229 HydrophobicContact CG2-CG2 4.02Å; V195-K233 HydrophobicContact CG2-CD 3.74Å
196I98.5Very high97.8Very high0 Ų063.4 Ų63.40%032%0.315CS..Hα-helixtrans-64.4-44.8178.2-68.7171.7000110.6L192 E198 K199 Y200 A204 T205 F213 P215 L226L192-I196 HydrophobicContact CD1-CD1 3.86Å; L192-I196 HydrophobicContact CD1-CG1 4.07Å; L192-I196 HydrophobicContact CD2-CD1 4.45Å; L192-I196 HydrophobicContact CG-CD1 3.8Å; L192-I196 HydrophobicContact CG-CG1 4.38Å; L192-I196 WeakPolarHBondContact O-CB 3.16Å; L192-I196 WeakPolarHBondContact O-CG1 3.36Å; L192-I196 PolarHBondContact O-N 3.04Å; I196-E198 VanDerWaalsContact C-N 3.3Å; I196-E198 PolarHBondContact O-N 3.05Å; I196-K199 PolarHBondContact O-N 2.96Å; I196-Y200 HydrophobicContact CG2-CD2 4.4Å; I196-Y200 PolarHBondContact O-N 3.41Å; I196-A204 HydrophobicContact CG2-CB 3.69Å; I196-A204 WeakPolarHBondContact CG2-O 3.26Å; I196-T205 HydrophobicContact CB-CG2 4.34Å; I196-T205 HydrophobicContact CG2-CG2 4.01Å; I196-F213 HydrophobicContact CD1-CB 3.51Å; I196-F213 HydrophobicContact CD1-CD2 3.77Å; I196-F213 HydrophobicContact CD1-CG 3.82Å; I196-P215 HydrophobicContact CD1-CG 4.25Å; I196-P215 HydrophobicContact CG2-CB 4.04Å; I196-L226 HydrophobicContact CG1-CD1 4.23Å; I196-L226 HydrophobicContact CG1-CD2 4.36Å
197K98.3Very high97.8Very high115 Ų11564.6 Ų64.650%0.532%0.319SS..Hα-helixtrans-59.2-42.3178.3-173178.3-179.7-171.80112.2K193 N194 G201 K202 T205K193-K197 VanDerWaalsContact O-CB 3.24Å; K193-K197 WeakPolarHBondContact O-CB 3.4Å; K193-K197 PolarHBondContact O-N 3.17Å; N194-K197 PolarHBondContact O-N 2.52Å; K197-G201 CarbonylContact O-C 3.55Å; K197-G201 WeakPolarHBondContact O-CA 3.25Å; K197-G201 PolarHBondContact O-N 3.3Å; K197-K202 HydrophobicContact CG-CB 4.49Å; K197-T205 HydrophobicContact CB-CG2 3.77Å; K197-T205 HydrophobicContact CG-CG2 4.5Å
198E98.1Very high97.5Very high149 Ų14961.9 Ų61.970%0.69631%0.309SS*.Hα-helixtrans-66-42.8179.6-174.5178.3-176.100111.3N194 V195 I196 K233N194-E198 VanDerWaalsContact O-CB 3.28Å; N194-E198 WeakPolarHBondContact O-CB 3.44Å; N194-E198 PolarHBondContact O-N 3.42Å; V195-E198 PolarHBondContact O-N 2.91Å; I196-E198 VanDerWaalsContact C-N 3.3Å; I196-E198 PolarHBondContact O-N 3.05Å; E198-K233 IonicContact OE2-NZ 3.68Å; E198-K233 PolarHBondContact OE2-NZ 3.48Å; E198-K233 VanDerWaalsContact OE2-NZ 3.11Å
199K97.8Very high97.2Very high114 Ų11464.1 Ų64.150%0.49632%0.321SS..Hα-helixtrans-85-38.5-175-169.6170178.8-178.60114.3V195 I196 E222 L226V195-K199 WeakPolarHBondContact O-CB 3.04Å; V195-K199 PolarHBondContact O-N 2.65Å; I196-K199 PolarHBondContact O-N 2.96Å; K199-E222 IonicContact NZ-OE1 3.89Å; K199-E222 PolarHBondContact NZ-OE1 3.17Å; K199-E222 IonicContact NZ-OE2 3.68Å; K199-E222 PolarHBondContact NZ-OE2 3.13Å; K199-L226 HydrophobicContact CD-CD2 4.3Å
200Y96.8Very high97.1Very high75 Ų7563.8 Ų63.829%0.29432%0.319SS..Hα-helixtrans-120.91.3-170.4-61.5-70.8000114.1I196 P215 I217 E222 L226I196-Y200 HydrophobicContact CG2-CD2 4.4Å; I196-Y200 PolarHBondContact O-N 3.41Å; Y200-P215 HydrophobicContact CD2-CB 4.37Å; Y200-I217 HydrophobicContact CE1-CG2 3.9Å; Y200-I217 HydrophobicContact CE2-CG2 3.94Å; Y200-E222 WeakPolarHBondContact OH-CG 3.34Å; Y200-E222 PolarHBondContact OH-OE1 3.25Å; Y200-L226 HydrophobicContact CE2-CD1 4.03Å; Y200-L226 HydrophobicContact CE2-CD2 4.07Å
201G96.9Very high97.1Very high32 Ų3258.6 Ų58.633%0.3330%0.296SS..  trans83.9169.4-178.700000113.7K197 D203 A204K197-G201 CarbonylContact O-C 3.55Å; K197-G201 WeakPolarHBondContact O-CA 3.25Å; K197-G201 PolarHBondContact O-N 3.3Å; G201-D203 VanDerWaalsContact C-N 3.26Å; G201-D203 PolarHBondContact O-N 3Å; G201-A204 PolarHBondContact O-N 3.47Å
202K95.4Very high97Very high141 Ų14156.6 Ų56.661%0.61329%0.285SS*.G310 helixtrans-60.9-33.2-175.267.7179.9-176.8175.20113.4K197 A204 T205K197-K202 HydrophobicContact CG-CB 4.49Å; K202-A204 PolarHBondContact O-N 3.47Å; K202-T205 PolarHBondContact O-N 2.95Å; K202-T205 PolarHBondContact O-OG1 2.92Å
203D94.6Very high97Very high118 Ų11856.6 Ų56.663%0.63129%0.285SS*.G310 helixtrans-71-22.8-173.5-56-38.3000111.5G201 T205 N206G201-D203 VanDerWaalsContact C-N 3.26Å; G201-D203 PolarHBondContact O-N 3Å; D203-T205 PolarHBondContact O-N 3.33Å; D203-N206 PolarHBondContact O-ND2 3.43Å
204A95.6Very high97Very high12 Ų1253.5 Ų53.510%0.09928%0.276CS..G310 helixtrans-74.8-5172.700000113.9I196 G201 K202 P215I196-A204 HydrophobicContact CG2-CB 3.69Å; I196-A204 WeakPolarHBondContact CG2-O 3.26Å; G201-A204 PolarHBondContact O-N 3.47Å; K202-A204 PolarHBondContact O-N 3.47Å; A204-P215 HydrophobicContact CB-CB 4.29Å
205T96.9Very high96.8Very high20 Ų2049 Ų4912%0.12325%0.252CS..G310 helixtrans-98.810.317968.40000114.3K193 I196 K197 K202 D203 F213K193-T205 HydrophobicContact CG-CG2 3.98Å; K193-T205 WeakPolarHBondContact O-CG2 3.34Å; I196-T205 HydrophobicContact CB-CG2 4.34Å; I196-T205 HydrophobicContact CG2-CG2 4.01Å; K197-T205 HydrophobicContact CB-CG2 3.77Å; K197-T205 HydrophobicContact CG-CG2 4.5Å; K202-T205 PolarHBondContact O-N 2.95Å; K202-T205 PolarHBondContact O-OG1 2.92Å; D203-T205 PolarHBondContact O-N 3.33Å; T205-F213 WeakPolarHBondContact O-CD1 3.38Å; T205-F213 WeakPolarHBondContact O-CE1 3.35Å
206N97.1Very high96.5Very high109 Ų10954.2 Ų54.258%0.58328%0.28SS*.  trans-66.7156.5162.9-66.9-45.4000109.8D203 F213 A214D203-N206 PolarHBondContact O-ND2 3.43Å; N206-F213 WeakPolarHBondContact O-CA 3.44Å; N206-A214 PolarHBondContact O-N 3.12Å; N206-A214 VanDerWaalsContact O-N 3.07Å
207V97.4Very high96.3Very high52 Ų5254.7 Ų54.732%0.31528%0.282SS..BIsolated β-bridgetrans-107.8147.3-174.8-60.40000111.5Y189 G211 G212 F213Y189-V207 WeakPolarHBondContact OH-CG1 3.42Å; V207-G211 VanDerWaalsContact CG1-O 3.26Å; V207-G211 WeakPolarHBondContact CG1-O 3.4Å; V207-G212 CarbonylContact C-O 3.5Å; V207-G212 WeakPolarHBondContact CA-O 3.15Å; V207-G212 WeakPolarHBondContact CB-O 3.31Å; V207-F213 HydrophobicContact CG1-CD1 4.16Å; V207-F213 HydrophobicContact CG1-CE1 4.2Å
208G94.2Very high96.1Very high8 Ų852.2 Ų52.28%0.08227%0.274CS..  trans-77.3-167.9170.200000112.7E210 G211 G212G208-E210 PolarHBondContact O-N 3.16Å; G208-E210 VanDerWaalsContact O-N 3.13Å; G208-G211 PolarHBondContact O-N 2.83Å; G208-G212 PolarHBondContact N-O 3.5Å
209D92.6Very high95.9Very high47 Ų4751.2 Ų51.225%0.25127%0.269SS..THydrogen-bonded Turntrans-56.8-31.2-177.3-80.1-7.1000112.8R15 H158 R400 R403R15-D209 WeakPolarHBondContact CD-OD2 3.44Å; H158-D209 PolarHBondContact O-N 3.08Å; D209-R400 PolarHBondContact O-NE 3.08Å; D209-R403 PolarHBondContact O-NH2 3.47Å
210E96.8Very high95.8Very high3 Ų346 Ų461%0.01425%0.247CC..THydrogen-bonded Turntrans-105.78.4-173-54.9-165.5162.600114.5N151 H158 G208 G212 H371 S373 A397N151-E210 PolarHBondContact ND2-OE2 2.77Å; H158-E210 IonicContact CE1-OE1 3.68Å; H158-E210 PolarHBondContact CE1-OE1 3.37Å; H158-E210 VanDerWaalsContact CE1-OE1 3.3Å; H158-E210 IonicContact ND1-OE1 2.78Å; G208-E210 PolarHBondContact O-N 3.16Å; G208-E210 VanDerWaalsContact O-N 3.13Å; E210-G212 VanDerWaalsContact C-N 3.33Å; E210-H371 IonicContact OE1-CE1 2.97Å; E210-H371 PolarHBondContact OE1-CE1 3.19Å; E210-H371 IonicContact OE1-NE2 3.25Å; E210-H371 IonicContact OE2-CE1 2.83Å; E210-H371 PolarHBondContact OE2-CE1 3.5Å; E210-H371 IonicContact OE2-NE2 3.08Å; E210-H371 PolarHBondContact OE2-NE2 2.81Å; E210-S373 WeakPolarHBondContact OE1-CA 3.39Å; E210-S373 WeakPolarHBondContact OE1-CB 3.47Å; E210-A397 WeakPolarHBondContact O-CB 3.24Å; E210-A397 PolarHBondContact O-N 2.99Å
211G97.8Very high95.8Very high0 Ų046.8 Ų46.80%025%0.252CS..SBendtrans86.9-5.1175.800000114.7Y189 V207 G208 A397Y189-G211 WeakPolarHBondContact CE2-O 3.32Å; Y189-G211 PolarHBondContact OH-O 2.94Å; V207-G211 VanDerWaalsContact CG1-O 3.26Å; V207-G211 WeakPolarHBondContact CG1-O 3.4Å; G208-G211 PolarHBondContact O-N 2.83Å; G211-A397 WeakPolarHBondContact O-CB 3.48Å
212G98.3Very high95.9Very high0 Ų047.3 Ų47.30%025%0.245CC..  trans-70.5154.2170.700000111.1N151 V152 N154 V207 G208 E210N151-G212 WeakPolarHBondContact O-CA 3.42Å; V152-G212 CarbonylContact O-C 3.57Å; V152-G212 WeakPolarHBondContact O-CA 3.47Å; N154-G212 WeakPolarHBondContact OD1-CA 3.46Å; N154-G212 PolarHBondContact OD1-N 3.39Å; N154-G212 PolarHBondContact OD1-O 2.64Å; N154-G212 VanDerWaalsContact OD1-O 3.14Å; V207-G212 CarbonylContact C-O 3.5Å; V207-G212 WeakPolarHBondContact CA-O 3.15Å; V207-G212 WeakPolarHBondContact CB-O 3.31Å; G208-G212 PolarHBondContact N-O 3.5Å; E210-G212 VanDerWaalsContact C-N 3.33Å
213F98.6Very high96Very high1 Ų140.6 Ų40.60%0.00422%0.216CC..BIsolated β-bridgetrans-69.4147.9177.3-61.4-64.2000111.2V152 I153 N154 Y189 L192 K193 I196 T205 N206 V207 P215V152-F213 PolarHBondContact O-N 3.1Å; I153-F213 CarbonylContact C-O 3.56Å; I153-F213 WeakPolarHBondContact CA-O 3.49Å; N154-F213 PolarHBondContact N-O 3.06Å; Y189-F213 HydrophobicContact CD1-CE2 4.48Å; Y189-F213 HydrophobicContact CD1-CZ 4.33Å; Y189-F213 HydrophobicContact CD2-CD2 4.35Å; Y189-F213 AromaticContact CD2-CE2 3.65Å; Y189-F213 HydrophobicContact CD2-CE2 3.65Å; Y189-F213 HydrophobicContact CD2-CZ 4.16Å; Y189-F213 HydrophobicContact CE1-CE2 4.2Å; Y189-F213 AromaticContact CE1-CZ 3.72Å; Y189-F213 HydrophobicContact CE1-CZ 3.72Å; Y189-F213 AromaticContact CE2-CD2 3.92Å; Y189-F213 HydrophobicContact CE2-CD2 3.92Å; Y189-F213 HydrophobicContact CE2-CE1 4.35Å; Y189-F213 AromaticContact CE2-CE2 3.34Å; Y189-F213 HydrophobicContact CE2-CE2 3.34Å; Y189-F213 AromaticContact CE2-CZ 3.57Å; Y189-F213 HydrophobicContact CE2-CZ 3.57Å; Y189-F213 HydrophobicContact CG-CE2 4.23Å; Y189-F213 AromaticContact CZ-CE1 3.95Å; Y189-F213 AromaticContact CZ-CE2 3.65Å; Y189-F213 AromaticContact CZ-CZ 3.31Å; Y189-F213 WeakPolarHBondContact O-CE2 3.41Å; Y189-F213 WeakPolarHBondContact OH-CZ 3.48Å; L192-F213 HydrophobicContact CB-CE2 4.34Å; L192-F213 HydrophobicContact CD2-CD2 3.86Å; L192-F213 HydrophobicContact CD2-CE2 4.29Å; L192-F213 HydrophobicContact CG-CD2 3.91Å; L192-F213 HydrophobicContact CG-CE2 4.22Å; K193-F213 HydrophobicContact CB-CE1 4Å; K193-F213 HydrophobicContact CB-CE2 3.77Å; K193-F213 HydrophobicContact CB-CZ 3.33Å; K193-F213 HydrophobicContact CD-CE1 3.93Å; K193-F213 HydrophobicContact CD-CZ 3.84Å; K193-F213 HydrophobicContact CG-CE1 3.65Å; K193-F213 HydrophobicContact CG-CE2 4.36Å; K193-F213 HydrophobicContact CG-CZ 3.52Å; I196-F213 HydrophobicContact CD1-CB 3.51Å; I196-F213 HydrophobicContact CD1-CD2 3.77Å; I196-F213 HydrophobicContact CD1-CG 3.82Å; T205-F213 WeakPolarHBondContact O-CD1 3.38Å; T205-F213 WeakPolarHBondContact O-CE1 3.35Å; N206-F213 WeakPolarHBondContact O-CA 3.44Å; V207-F213 HydrophobicContact CG1-CD1 4.16Å; V207-F213 HydrophobicContact CG1-CE1 4.2Å; F213-P215 WeakPolarHBondContact O-CD 3.47Å
214A97.1Very high96.2Very high25 Ų2535 Ų3521%0.20719%0.186CC..  trans-115.763.2178.700000111.6A159 N206A159-A214 HydrophobicContact CB-CB 3.75Å; N206-A214 PolarHBondContact O-N 3.12Å; N206-A214 VanDerWaalsContact O-N 3.07Å
215P95.9Very high96.3Very high0 Ų037.4 Ų37.40%020%0.195CC..  trans-64.6148.7177.729.9-34.1000110.5I153 N161 I196 Y200 A204 F213 I217 L226I153-P215 HydrophobicContact CG2-CG 4.11Å; N161-P215 VanDerWaalsContact CB-O 3.24Å; N161-P215 WeakPolarHBondContact CB-O 3.15Å; N161-P215 PolarHBondContact ND2-O 3.21Å; I196-P215 HydrophobicContact CD1-CG 4.25Å; I196-P215 HydrophobicContact CG2-CB 4.04Å; Y200-P215 HydrophobicContact CD2-CB 4.37Å; A204-P215 HydrophobicContact CB-CB 4.29Å; F213-P215 WeakPolarHBondContact O-CD 3.47Å; P215-I217 HydrophobicContact CB-CG2 4.31Å; P215-I217 HydrophobicContact CG-CD1 4.08Å; P215-I217 HydrophobicContact CG-CG1 4.12Å; P215-I217 PolarHBondContact O-N 3.5Å; P215-L226 HydrophobicContact CG-CD1 4.4Å
216N91.8Very high96.4Very high118 Ų11836.5 Ų36.563%0.63119%0.19SC*.  trans-80.166179.3-16930000111.5
217I94.2Very high96.5Very high9 Ų931.3 Ų31.35%0.04616%0.162CC..  trans-108.5150.8176.160.7174.6000109.7K162 L163 Y200 P215 E222 L226K162-I217 CarbonylContact C-O 3.55Å; L163-I217 WeakPolarHBondContact CA-O 3.47Å; L163-I217 HydrophobicContact CB-CG1 4.31Å; L163-I217 WeakPolarHBondContact CB-O 3.43Å; L163-I217 HydrophobicContact CD1-CD1 4.17Å; L163-I217 HydrophobicContact CD1-CG1 4.13Å; L163-I217 HydrophobicContact CD2-CD1 4.05Å; L163-I217 HydrophobicContact CD2-CG1 4.11Å; L163-I217 HydrophobicContact CG-CG1 4.44Å; L163-I217 PolarHBondContact N-O 2.84Å; Y200-I217 HydrophobicContact CE1-CG2 3.9Å; Y200-I217 HydrophobicContact CE2-CG2 3.94Å; P215-I217 HydrophobicContact CB-CG2 4.31Å; P215-I217 HydrophobicContact CG-CD1 4.08Å; P215-I217 HydrophobicContact CG-CG1 4.12Å; P215-I217 PolarHBondContact O-N 3.5Å; I217-E222 HydrophobicContact CB-CG 4.22Å; I217-E222 HydrophobicContact CD1-CB 4.39Å; I217-E222 HydrophobicContact CD1-CG 4.22Å; I217-E222 HydrophobicContact CG2-CG 3.79Å; I217-L226 HydrophobicContact CD1-CD1 4.21Å
218L93.6Very high96.5Very high64 Ų6433.6 Ų33.634%0.33517%0.168SC..  trans-103.7-49.3174.8172.963.2000110.5K162 N220 D260K162-L218 HydrophobicContact CB-CB 4.08Å; K162-L218 HydrophobicContact CB-CD1 3.86Å; K162-L218 HydrophobicContact CD-CD1 4.46Å; L218-N220 PolarHBondContact O-N 2.76Å; L218-D260 HydrophobicContact CD1-CB 3.83Å; L218-D260 WeakPolarHBondContact CD1-OD1 3.31Å
219E95.3Very high96.7Very high127 Ų12736 Ų3659%0.59318%0.181SC*.  trans-69.9120.8-175.7-66-63.7161.400112.2K221 E222E219-K221 PolarHBondContact O-N 2.7Å; E219-E222 HydrophobicContact CB-CB 4.21Å; E219-E222 VanDerWaalsContact O-CB 3.32Å; E219-E222 WeakPolarHBondContact O-CB 3.44Å; E219-E222 PolarHBondContact O-N 3.16Å
220N95.6Very high97Very high5 Ų533.8 Ų33.83%0.02717%0.169CC..Hα-helixtrans-61.1-31.5177.3-58.2-68.5000112.4L163 M165 F168 L218 E222 G223 L224 F283L163-N220 HydrophobicContact CD1-CB 4.38Å; L163-N220 VanDerWaalsContact CD1-OD1 3.25Å; L163-N220 WeakPolarHBondContact CD1-OD1 3.46Å; M165-N220 VanDerWaalsContact CB-OD1 3.31Å; M165-N220 WeakPolarHBondContact CB-OD1 3.36Å; M165-N220 HydrophobicContact CE-CB 4.04Å; M165-N220 HydrophobicContact CG-CB 4.32Å; M165-N220 WeakPolarHBondContact CG-OD1 3.27Å; M165-N220 PolarHBondContact N-OD1 3.36Å; M165-N220 HydrophobicContact SD-CB 3.63Å; F168-N220 HydrophobicContact CE1-CB 4.43Å; F168-N220 WeakPolarHBondContact CE1-O 3.47Å; F168-N220 HydrophobicContact CZ-CB 4.03Å; L218-N220 PolarHBondContact O-N 2.76Å; N220-E222 VanDerWaalsContact C-N 3.27Å; N220-E222 PolarHBondContact O-N 3.38Å; N220-G223 PolarHBondContact O-N 2.97Å; N220-G223 VanDerWaalsContact O-N 3.14Å; N220-L224 PolarHBondContact O-N 2.7Å; N220-F283 HydrophobicContact CB-CE2 4.13Å; N220-F283 HydrophobicContact CB-CZ 3.96Å
221K97.1Very high97.1Very high92 Ų9234 Ų3440%0.417%0.17SC..Hα-helixtrans-60.1-36.3174.5-170.5172.5-177164.20112.5E219 G223 L224 E225 F283 D286 Y287E219-K221 PolarHBondContact O-N 2.7Å; K221-G223 VanDerWaalsContact C-N 3.31Å; K221-G223 PolarHBondContact O-N 2.65Å; K221-L224 PolarHBondContact O-N 3.48Å; K221-E225 PolarHBondContact O-N 2.69Å; K221-F283 HydrophobicContact CB-CE1 4.13Å; K221-D286 IonicContact NZ-OD2 2.73Å; K221-Y287 WeakPolarHBondContact CE-OH 3.33Å; K221-Y287 HydrophobicContact CG-CE2 4.14Å; K221-Y287 WeakPolarHBondContact CG-OH 3.39Å
222E97.6Very high97.2Very high42 Ų4235.9 Ų35.920%0.19619%0.189CC..Hα-helixtrans-65-37.2176.9176.959.5-133.600111.1K199 Y200 I217 E219 N220 L224 E225 L226K199-E222 IonicContact NZ-OE1 3.89Å; K199-E222 PolarHBondContact NZ-OE1 3.17Å; K199-E222 IonicContact NZ-OE2 3.68Å; K199-E222 PolarHBondContact NZ-OE2 3.13Å; Y200-E222 WeakPolarHBondContact OH-CG 3.34Å; Y200-E222 PolarHBondContact OH-OE1 3.25Å; I217-E222 HydrophobicContact CB-CG 4.22Å; I217-E222 HydrophobicContact CD1-CB 4.39Å; I217-E222 HydrophobicContact CD1-CG 4.22Å; I217-E222 HydrophobicContact CG2-CG 3.79Å; E219-E222 HydrophobicContact CB-CB 4.21Å; E219-E222 VanDerWaalsContact O-CB 3.32Å; E219-E222 WeakPolarHBondContact O-CB 3.44Å; E219-E222 PolarHBondContact O-N 3.16Å; N220-E222 VanDerWaalsContact C-N 3.27Å; N220-E222 PolarHBondContact O-N 3.38Å; E222-L224 VanDerWaalsContact C-N 3.32Å; E222-L224 PolarHBondContact O-N 2.99Å; E222-E225 PolarHBondContact O-N 2.69Å; E222-L226 VanDerWaalsContact O-CG 3.31Å; E222-L226 WeakPolarHBondContact O-CG 3.13Å; E222-L226 PolarHBondContact O-N 3Å; E222-L226 WeakPolarHBondContact OE1-CG 2.86Å
223G97.8Very high97.2Very high0 Ų041.2 Ų41.20%021%0.213CC..Hα-helixtrans-57.4-44.9171.900000112.3N220 K221 L226 L227N220-G223 PolarHBondContact O-N 2.97Å; N220-G223 VanDerWaalsContact O-N 3.14Å; K221-G223 VanDerWaalsContact C-N 3.31Å; K221-G223 PolarHBondContact O-N 2.65Å; G223-L226 PolarHBondContact O-N 3.37Å; G223-L227 WeakPolarHBondContact O-CG 3.26Å; G223-L227 PolarHBondContact O-N 2.79Å; G223-L227 VanDerWaalsContact O-N 3.14Å
224L98.6Very high97.2Very high0 Ų042 Ų420%022%0.219CC..Hα-helixtrans-67-38.7177.3-65171.9000112.9F168 N220 K221 E222 L227 K228 I242 M244 F283 Y287 V289F168-L224 HydrophobicContact CD1-CD2 3.94Å; F168-L224 HydrophobicContact CD1-CG 4.18Å; F168-L224 HydrophobicContact CE1-CD2 4.29Å; F168-L224 HydrophobicContact CE1-CG 4.09Å; N220-L224 PolarHBondContact O-N 2.7Å; K221-L224 PolarHBondContact O-N 3.48Å; E222-L224 VanDerWaalsContact C-N 3.32Å; E222-L224 PolarHBondContact O-N 2.99Å; L224-L227 PolarHBondContact O-N 2.89Å; L224-K228 WeakPolarHBondContact O-CB 3.29Å; L224-K228 PolarHBondContact O-N 3.03Å; L224-I242 HydrophobicContact CD2-CD1 4.17Å; L224-I242 HydrophobicContact CD2-CG2 3.77Å; L224-M244 HydrophobicContact CD1-SD 4.25Å; L224-M244 HydrophobicContact CD2-CG 4.49Å; L224-M244 HydrophobicContact CD2-SD 3.98Å; L224-F283 HydrophobicContact CD1-CB 3.77Å; L224-F283 HydrophobicContact CD1-CD1 3.76Å; L224-F283 HydrophobicContact CD1-CD2 3.78Å; L224-F283 HydrophobicContact CD1-CE1 4.27Å; L224-F283 HydrophobicContact CD1-CE2 4.27Å; L224-F283 HydrophobicContact CD1-CG 3.5Å; L224-F283 VanDerWaalsContact CD1-CG 3.5Å; L224-Y287 HydrophobicContact CB-CD1 3.78Å; L224-Y287 HydrophobicContact CB-CD2 3.95Å; L224-Y287 HydrophobicContact CB-CE1 3.78Å; L224-Y287 HydrophobicContact CB-CE2 3.94Å; L224-Y287 HydrophobicContact CB-CG 3.89Å; L224-Y287 HydrophobicContact CD1-CD2 3.57Å; L224-Y287 HydrophobicContact CD1-CE2 3.83Å; L224-Y287 HydrophobicContact CD1-CG 4.13Å; L224-Y287 HydrophobicContact CG-CD2 4.33Å; L224-Y287 HydrophobicContact CG-CG 4.47Å; L224-V289 HydrophobicContact CD2-CG2 4.07Å
225E98.5Very high97.3Very high63 Ų6343.7 Ų43.729%0.29424%0.239SC..Hα-helixtrans-64.5-39.1174.9-73.9-59.5159.100112.6K221 E222 K228 T229 Y287K221-E225 PolarHBondContact O-N 2.69Å; E222-E225 PolarHBondContact O-N 2.69Å; E225-K228 PolarHBondContact O-N 3.25Å; E225-T229 WeakPolarHBondContact O-CB 3.49Å; E225-T229 PolarHBondContact O-N 2.95Å; E225-T229 PolarHBondContact O-OG1 2.87Å; E225-Y287 VanDerWaalsContact CD-OH 3.27Å; E225-Y287 HydrophobicContact CG-CE1 4.11Å; E225-Y287 WeakPolarHBondContact CG-OH 3.02Å; E225-Y287 WeakPolarHBondContact OE1-CE1 3.23Å; E225-Y287 PolarHBondContact OE1-OH 2.7Å
226L98.6Very high97.4Very high2 Ų245 Ų451%0.0125%0.245CC..Hα-helixtrans-61.3-44.5173.8-69.6169000111.3I153 L192 V195 I196 K199 Y200 P215 I217 E222 G223 T229 A230I153-L226 HydrophobicContact CD1-CB 4.09Å; I153-L226 HydrophobicContact CD1-CD1 4.31Å; L192-L226 HydrophobicContact CD1-CB 3.96Å; V195-L226 HydrophobicContact CG1-CD2 3.69Å; I196-L226 HydrophobicContact CG1-CD1 4.23Å; I196-L226 HydrophobicContact CG1-CD2 4.36Å; K199-L226 HydrophobicContact CD-CD2 4.3Å; Y200-L226 HydrophobicContact CE2-CD1 4.03Å; Y200-L226 HydrophobicContact CE2-CD2 4.07Å; P215-L226 HydrophobicContact CG-CD1 4.4Å; I217-L226 HydrophobicContact CD1-CD1 4.21Å; E222-L226 VanDerWaalsContact O-CG 3.31Å; E222-L226 WeakPolarHBondContact O-CG 3.13Å; E222-L226 PolarHBondContact O-N 3Å; E222-L226 WeakPolarHBondContact OE1-CG 2.86Å; G223-L226 PolarHBondContact O-N 3.37Å; L226-T229 PolarHBondContact O-N 2.81Å; L226-A230 WeakPolarHBondContact O-CB 3.32Å; L226-A230 PolarHBondContact O-N 3.12Å
227L98.6Very high97.7Very high0 Ų043.8 Ų43.80%024%0.242CC..Hα-helixtrans-63.3-48.7176-66.7-165000112.1V152 I153 F168 I170 L192 G223 L224 T229 A230 I231 I242V152-L227 HydrophobicContact CG2-CD1 4.34Å; V152-L227 HydrophobicContact CG2-CD2 3.46Å; V152-L227 VanDerWaalsContact CG2-CD2 3.46Å; I153-L227 HydrophobicContact CD1-CD2 3.7Å; I153-L227 HydrophobicContact CD1-CG 4.03Å; I153-L227 HydrophobicContact CG1-CD2 3.99Å; F168-L227 HydrophobicContact CB-CD1 3.77Å; I170-L227 HydrophobicContact CG2-CD1 4.13Å; I170-L227 HydrophobicContact CG2-CD2 4.36Å; L192-L227 HydrophobicContact CD1-CD2 4.1Å; L192-L227 HydrophobicContact CD2-CD2 3.67Å; G223-L227 WeakPolarHBondContact O-CG 3.26Å; G223-L227 PolarHBondContact O-N 2.79Å; G223-L227 VanDerWaalsContact O-N 3.14Å; L224-L227 PolarHBondContact O-N 2.89Å; L227-T229 VanDerWaalsContact C-N 3.27Å; L227-T229 PolarHBondContact O-N 2.88Å; L227-A230 PolarHBondContact O-N 2.96Å; L227-A230 VanDerWaalsContact O-N 3.15Å; L227-I231 WeakPolarHBondContact O-CB 3.36Å; L227-I231 WeakPolarHBondContact O-CD1 3.41Å; L227-I231 WeakPolarHBondContact O-CG1 3.24Å; L227-I231 PolarHBondContact O-N 2.88Å; L227-I242 HydrophobicContact CB-CD1 3.93Å; L227-I242 HydrophobicContact CD1-CD1 4.19Å; L227-I242 HydrophobicContact CD1-CG1 4.25Å; L227-I242 HydrophobicContact CD1-CG2 4.21Å
228K98.6Very high97.9Very high100 Ų10050.3 Ų50.344%0.43528%0.276SS..Hα-helixtrans-55.5-44.9177.1-179.2179.4177.1179.20111.4L224 E225 G232 Y287L224-K228 WeakPolarHBondContact O-CB 3.29Å; L224-K228 PolarHBondContact O-N 3.03Å; E225-K228 PolarHBondContact O-N 3.25Å; K228-G232 PolarHBondContact O-N 2.78Å; K228-Y287 HydrophobicContact CB-CD1 4.48Å; K228-Y287 HydrophobicContact CD-CD1 4.1Å; K228-Y287 HydrophobicContact CD-CE1 4.13Å
229T98.7Very high98.1Very high59 Ų5950.4 Ų50.436%0.36227%0.274SS..Hα-helixtrans-63.8-45.6177.1-58.60000111.6V195 E225 L226 L227 G232 K233V195-T229 HydrophobicContact CG1-CG2 4.1Å; V195-T229 HydrophobicContact CG2-CG2 4.02Å; E225-T229 WeakPolarHBondContact O-CB 3.49Å; E225-T229 PolarHBondContact O-N 2.95Å; E225-T229 PolarHBondContact O-OG1 2.87Å; L226-T229 PolarHBondContact O-N 2.81Å; L227-T229 VanDerWaalsContact C-N 3.27Å; L227-T229 PolarHBondContact O-N 2.88Å; T229-G232 PolarHBondContact O-N 2.97Å; T229-K233 WeakPolarHBondContact O-CG 3.28Å; T229-K233 PolarHBondContact O-N 2.86Å
230A98.8Very high98.3Very high0 Ų044.4 Ų44.40%025%0.246CC..Hα-helixtrans-65.2-42.6179.900000112.7V188 L192 L226 L227 G232 K233 A234V188-A230 HydrophobicContact CG1-CB 4.31Å; L192-A230 HydrophobicContact CB-CB 3.68Å; L192-A230 HydrophobicContact CD1-CB 3.95Å; L192-A230 HydrophobicContact CG-CB 4.41Å; L226-A230 WeakPolarHBondContact O-CB 3.32Å; L226-A230 PolarHBondContact O-N 3.12Å; L227-A230 PolarHBondContact O-N 2.96Å; L227-A230 VanDerWaalsContact O-N 3.15Å; A230-G232 VanDerWaalsContact C-N 3.34Å; A230-K233 PolarHBondContact O-N 3.05Å; A230-A234 WeakPolarHBondContact O-CB 3.48Å; A230-A234 PolarHBondContact O-N 3.47Å
231I98.8Very high98.5Very high7 Ų745.4 Ų45.44%0.03625%0.252CS..Hα-helixtrans-60.7-44.9175-68163.4000110.3I170 V188 L227 A234 G235 Y236 V240 I242I170-I231 HydrophobicContact CG2-CD1 4.16Å; I170-I231 HydrophobicContact CG2-CG1 4.49Å; V188-I231 HydrophobicContact CG1-CG1 3.81Å; V188-I231 HydrophobicContact CG2-CG1 4.46Å; L227-I231 WeakPolarHBondContact O-CB 3.36Å; L227-I231 WeakPolarHBondContact O-CD1 3.41Å; L227-I231 WeakPolarHBondContact O-CG1 3.24Å; L227-I231 PolarHBondContact O-N 2.88Å; I231-A234 PolarHBondContact O-N 2.85Å; I231-G235 PolarHBondContact O-N 3.21Å; I231-G235 VanDerWaalsContact O-N 3.17Å; I231-Y236 PolarHBondContact O-N 2.92Å; I231-Y236 VanDerWaalsContact O-N 3.13Å; I231-V240 HydrophobicContact CD1-CB 4.29Å; I231-V240 HydrophobicContact CD1-CG1 3.68Å; I231-V240 HydrophobicContact CG1-CB 4.29Å; I231-V240 HydrophobicContact CG1-CG1 3.9Å; I231-V240 HydrophobicContact CG2-CB 4.08Å; I231-I242 HydrophobicContact CD1-CD1 4.45Å; I231-I242 HydrophobicContact CD1-CG1 4.28Å
232G98.8Very high98.6Very high39 Ų3941 Ų4140%0.40223%0.233SC..Hα-helixtrans-62.5-47.9176.400000112.8K228 T229 A230 A234 G235K228-G232 PolarHBondContact O-N 2.78Å; T229-G232 PolarHBondContact O-N 2.97Å; A230-G232 VanDerWaalsContact C-N 3.34Å; G232-A234 VanDerWaalsContact C-N 3.26Å; G232-A234 PolarHBondContact O-N 2.82Å; G232-G235 PolarHBondContact O-N 3.29Å
233K98.7Very high98.6Very high113 Ų11339 Ų3949%0.49122%0.224SC..Hα-helixtrans-61.5-33.4176.5-76.1-168.3179.8-172.50112.5V195 E198 T229 A230 G235V195-K233 HydrophobicContact CG2-CD 3.74Å; E198-K233 IonicContact OE2-NZ 3.68Å; E198-K233 PolarHBondContact OE2-NZ 3.48Å; E198-K233 VanDerWaalsContact OE2-NZ 3.11Å; T229-K233 WeakPolarHBondContact O-CG 3.28Å; T229-K233 PolarHBondContact O-N 2.86Å; A230-K233 PolarHBondContact O-N 3.05Å; K233-G235 VanDerWaalsContact C-N 3.29Å
234A98.6Very high98.7Very high17 Ų1739 Ų3914%0.1422%0.224CC..Hα-helixtrans-78.2-10.4176.200000113.8V188 N191 A230 I231 G232 Y236V188-A234 HydrophobicContact CG2-CB 3.8Å; N191-A234 HydrophobicContact CB-CB 4.39Å; A230-A234 WeakPolarHBondContact O-CB 3.48Å; A230-A234 PolarHBondContact O-N 3.47Å; I231-A234 PolarHBondContact O-N 2.85Å; G232-A234 VanDerWaalsContact C-N 3.26Å; G232-A234 PolarHBondContact O-N 2.82Å; A234-Y236 HydrophobicContact CB-CD2 3.71Å; A234-Y236 HydrophobicContact CB-CE2 4.19Å; A234-Y236 VanDerWaalsContact O-CD2 3.31Å; A234-Y236 WeakPolarHBondContact O-CD2 3.14Å; A234-Y236 WeakPolarHBondContact O-CE2 3.34Å
235G98.6Very high98.7Very high61 Ų6139 Ų3963%0.62922%0.224SC*.THydrogen-bonded Turntrans77.825.8178.800000114.7I231 G232 K233I231-G235 PolarHBondContact O-N 3.21Å; I231-G235 VanDerWaalsContact O-N 3.17Å; G232-G235 PolarHBondContact O-N 3.29Å; K233-G235 VanDerWaalsContact C-N 3.29Å
236Y98.8Very high98.7Very high27 Ų2736 Ų3611%0.10621%0.21CC..  trans-119.323.1-173.2-63.5-57.8000115.4R183 I184 E187 V188 I231 A234 D238 K239 V240R183-Y236 PolarHBondContact NH1-OH 3.46Å; I184-Y236 HydrophobicContact CB-CD2 4.44Å; I184-Y236 HydrophobicContact CB-CE2 4.42Å; I184-Y236 HydrophobicContact CD1-CD1 4.16Å; I184-Y236 HydrophobicContact CD1-CE1 4.15Å; I184-Y236 HydrophobicContact CG1-CD1 4.02Å; I184-Y236 HydrophobicContact CG1-CD2 4.4Å; I184-Y236 HydrophobicContact CG1-CE1 3.75Å; I184-Y236 HydrophobicContact CG1-CE2 4.16Å; I184-Y236 HydrophobicContact CG1-CG 4.34Å; I184-Y236 HydrophobicContact CG2-CD1 4.29Å; I184-Y236 HydrophobicContact CG2-CD2 3.8Å; I184-Y236 HydrophobicContact CG2-CE2 4.27Å; I184-Y236 HydrophobicContact CG2-CG 3.82Å; E187-Y236 HydrophobicContact CB-CE2 4.09Å; E187-Y236 WeakPolarHBondContact OE2-CE2 3.4Å; E187-Y236 VanDerWaalsContact OE2-CZ 3.24Å; E187-Y236 PolarHBondContact OE2-OH 3.18Å; V188-Y236 HydrophobicContact CG2-CD2 3.98Å; I231-Y236 PolarHBondContact O-N 2.92Å; I231-Y236 VanDerWaalsContact O-N 3.13Å; A234-Y236 HydrophobicContact CB-CD2 3.71Å; A234-Y236 HydrophobicContact CB-CE2 4.19Å; A234-Y236 VanDerWaalsContact O-CD2 3.31Å; A234-Y236 WeakPolarHBondContact O-CD2 3.14Å; A234-Y236 WeakPolarHBondContact O-CE2 3.34Å; Y236-D238 VanDerWaalsContact C-N 3.26Å; Y236-D238 PolarHBondContact O-N 3.09Å; Y236-K239 HydrophobicContact CD1-CD 4.21Å; Y236-K239 PolarHBondContact O-N 2.9Å; Y236-V240 PolarHBondContact O-N 2.94Å
237T98.4Very high98.6Very high93 Ų9336 Ų3657%0.57121%0.21SC*.THydrogen-bonded Turntrans-51.4-40.4-178.7-54.10000113.6K239T237-K239 VanDerWaalsContact C-N 3.31Å; T237-K239 PolarHBondContact O-N 2.94Å
238D97.9Very high98.6Very high145 Ų14536 Ų3678%0.77521%0.21SC*.THydrogen-bonded Turntrans-84.2-4.7-178.1-57.4-39.5000114.1Y236 R426Y236-D238 VanDerWaalsContact C-N 3.26Å; Y236-D238 PolarHBondContact O-N 3.09Å; D238-R426 PolarHBondContact O-NH2 3.19Å; D238-R426 VanDerWaalsContact O-NH2 3.12Å
239K98.6Very high98.6Very high66 Ų6632 Ų3229%0.28720%0.195SC..THydrogen-bonded Turntrans-113.7-22.8-174.7-70.3-168.6172.7-178.60114.1P172 V173 G174 E180 I184 Y236 T237P172-K239 CarbonylContact C-O 3.21Å; P172-K239 WeakPolarHBondContact CA-O 3.44Å; V173-K239 PolarHBondContact N-O 2.73Å; V173-K239 VanDerWaalsContact N-O 3.16Å; G174-K239 PolarHBondContact N-O 2.82Å; E180-K239 IonicContact OE1-NZ 3.72Å; E180-K239 PolarHBondContact OE1-NZ 2.89Å; I184-K239 HydrophobicContact CD1-CB 4.43Å; I184-K239 HydrophobicContact CD1-CD 3.77Å; Y236-K239 HydrophobicContact CD1-CD 4.21Å; Y236-K239 PolarHBondContact O-N 2.9Å; T237-K239 VanDerWaalsContact C-N 3.31Å; T237-K239 PolarHBondContact O-N 2.94Å
240V98.9Very high98.5Very high2 Ų231.8 Ų31.81%0.01219%0.19CC..  trans-115.9128.7-173.2179.80000110.4I170 L171 P172 I184 V188 I231 Y236I170-V240 HydrophobicContact CB-CG1 3.72Å; I170-V240 HydrophobicContact CG2-CG1 4.11Å; L171-V240 WeakPolarHBondContact O-CA 3.35Å; P172-V240 HydrophobicContact CB-CG2 4.4Å; I184-V240 HydrophobicContact CG2-CG2 3.37Å; V188-V240 HydrophobicContact CG2-CG2 4.45Å; I231-V240 HydrophobicContact CD1-CB 4.29Å; I231-V240 HydrophobicContact CD1-CG1 3.68Å; I231-V240 HydrophobicContact CG1-CB 4.29Å; I231-V240 HydrophobicContact CG1-CG1 3.9Å; I231-V240 HydrophobicContact CG2-CB 4.08Å; Y236-V240 PolarHBondContact O-N 2.94Å
241V98.9Very high98.4Very high25 Ų2531.8 Ų31.815%0.15219%0.19CC..EExtended strand (participates in β ladder)trans-114.5170.1171.6-62.10000109.7L171 V173 P288 V290L171-V241 HydrophobicContact CB-CG2 3.8Å; L171-V241 PolarHBondContact N-O 2.97Å; L171-V241 PolarHBondContact O-N 3.26Å; V173-V241 HydrophobicContact CB-CG2 4.37Å; V173-V241 HydrophobicContact CG1-CG2 3.67Å; V173-V241 HydrophobicContact CG2-CB 4.45Å; V173-V241 HydrophobicContact CG2-CG1 3.9Å; V173-V241 HydrophobicContact CG2-CG2 3.74Å; V241-P288 WeakPolarHBondContact CB-O 2.83Å; V241-P288 HydrophobicContact CG1-CB 4.43Å; V241-V290 HydrophobicContact CB-CG1 3.89Å; V241-V290 HydrophobicContact CB-CG2 3.88Å; V241-V290 HydrophobicContact CG1-CG1 4.06Å; V241-V290 HydrophobicContact CG2-CB 4.42Å; V241-V290 HydrophobicContact CG2-CG1 4.17Å; V241-V290 HydrophobicContact CG2-CG2 3.38Å
242I98.9Very high98.4Very high0 Ų034.1 Ų34.10%020%0.2CC..EExtended strand (participates in β ladder)trans-110.1139.4-175.2-64.7172.5000110.5M169 L224 L227 I231 M244 P288 V289 V290M169-I242 VanDerWaalsContact O-CA 3.31Å; M169-I242 WeakPolarHBondContact O-CA 3.19Å; M169-I242 WeakPolarHBondContact O-CG2 3.34Å; L224-I242 HydrophobicContact CD2-CD1 4.17Å; L224-I242 HydrophobicContact CD2-CG2 3.77Å; L227-I242 HydrophobicContact CB-CD1 3.93Å; L227-I242 HydrophobicContact CD1-CD1 4.19Å; L227-I242 HydrophobicContact CD1-CG1 4.25Å; L227-I242 HydrophobicContact CD1-CG2 4.21Å; I231-I242 HydrophobicContact CD1-CD1 4.45Å; I231-I242 HydrophobicContact CD1-CG1 4.28Å; I242-M244 HydrophobicContact CG2-CG 4.3Å; I242-P288 HydrophobicContact CD1-CG 4.22Å; I242-P288 HydrophobicContact CG1-CG 4.31Å; I242-P288 PolarHBondContact N-O 3.36Å; I242-V289 HydrophobicContact CB-CG2 4.1Å; I242-V289 HydrophobicContact CG2-CG2 3.95Å; I242-V289 WeakPolarHBondContact O-CA 3.34Å; I242-V290 PolarHBondContact O-N 2.99Å
243G98.9Very high98.3Very high0 Ų036.1 Ų36.10%020%0.195CC..EExtended strand (participates in β ladder)trans-116.8156.1165.300000109.9M169 L171 S291M169-G243 WeakPolarHBondContact CA-O 3.29Å; M169-G243 WeakPolarHBondContact CB-O 3.34Å; M169-G243 PolarHBondContact N-O 3.36Å; M169-G243 PolarHBondContact O-N 2.88Å; L171-G243 VanDerWaalsContact CD1-N 3.3Å; G243-S291 CarbonylContact C-O 3.53Å; G243-S291 VanDerWaalsContact CA-O 3.28Å; G243-S291 WeakPolarHBondContact CA-O 3.42Å
244M98.8Very high98.1Very high0 Ų036.6 Ų36.60%021%0.213CC..EExtended strand (participates in β ladder)trans-134.1139.6176.4-58.9176.465.700109.4M165 E167 F168 L224 I242 F283 V289 S291 I292 E293M165-M244 HydrophobicContact SD-CE 3.32Å; M165-M244 WeakPolarHBondContact SD-CE 3.3Å; E167-M244 WeakPolarHBondContact O-CA 3.3Å; F168-M244 HydrophobicContact CD1-CE 4.19Å; F168-M244 HydrophobicContact CE1-CE 3.69Å; F168-M244 HydrophobicContact CZ-CE 4.2Å; L224-M244 HydrophobicContact CD1-SD 4.25Å; L224-M244 HydrophobicContact CD2-CG 4.49Å; L224-M244 HydrophobicContact CD2-SD 3.98Å; I242-M244 HydrophobicContact CG2-CG 4.3Å; M244-F283 HydrophobicContact CE-CD2 3.97Å; M244-F283 HydrophobicContact CE-CE2 4.1Å; M244-F283 HydrophobicContact SD-CD2 4.08Å; M244-V289 HydrophobicContact SD-CG1 4.29Å; M244-V289 HydrophobicContact SD-CG2 4.16Å; M244-S291 PolarHBondContact N-O 3.3Å; M244-I292 HydrophobicContact CB-CG1 4.46Å; M244-I292 CarbonylContact O-C 3.48Å; M244-I292 WeakPolarHBondContact O-CA 3.47Å; M244-E293 PolarHBondContact O-N 3.45Å
245D98.7Very high98Very high1 Ų137.7 Ų37.71%0.00523%0.226CC..EExtended strand (participates in β ladder)trans-110.5117.6157.1167.824.8000107.6Q166 E167 M169 A247 E293 K394Q166-D245 PolarHBondContact N-O 3.03Å; Q166-D245 PolarHBondContact NE2-OD2 2.97Å; E167-D245 HydrophobicContact CB-CB 3.81Å; E167-D245 HydrophobicContact CG-CB 3.72Å; E167-D245 PolarHBondContact N-O 3.32Å; E167-D245 PolarHBondContact O-N 2.81Å; E167-D245 WeakPolarHBondContact OE2-CB 3.16Å; M169-D245 HydrophobicContact CE-CB 4.14Å; D245-A247 PolarHBondContact OD1-N 3.47Å; D245-E293 HydrophobicContact CB-CB 3.96Å; D245-E293 HydrophobicContact CB-CG 4.23Å; D245-K394 IonicContact OD2-NZ 3.98Å
246V98.6Very high98Very high0 Ų039.2 Ų39.20%022%0.215CC..  trans-84.9-34.7-177.1-175.40000110M165 A248 F251 Y280 I292 E293M165-V246 HydrophobicContact CE-CG1 4.31Å; M165-V246 HydrophobicContact CG-CB 4.38Å; M165-V246 HydrophobicContact CG-CG1 3.74Å; M165-V246 HydrophobicContact CG-CG2 4.43Å; M165-V246 HydrophobicContact SD-CG1 4.34Å; M165-V246 HydrophobicContact SD-CG2 4.28Å; V246-A248 VanDerWaalsContact C-N 3.31Å; V246-A248 HydrophobicContact CG1-CB 4.15Å; V246-A248 PolarHBondContact O-N 3.42Å; V246-F251 HydrophobicContact CG1-CE1 3.94Å; V246-F251 HydrophobicContact CG1-CZ 3.45Å; V246-F251 VanDerWaalsContact CG1-CZ 3.45Å; V246-F251 WeakPolarHBondContact O-CE1 3.42Å; V246-Y280 HydrophobicContact CG1-CE1 4.22Å; V246-Y280 WeakPolarHBondContact CG1-OH 3.35Å; V246-Y280 HydrophobicContact CG2-CE1 3.81Å; V246-I292 HydrophobicContact CG2-CG2 3.77Å; V246-E293 PolarHBondContact N-O 2.61Å
247A97.6Very high98Very high2 Ų238 Ų382%0.01721%0.21CC..  trans5048.9-171.700000112.6Q166 D245 S249 E250Q166-A247 HydrophobicContact CB-CB 3.81Å; Q166-A247 HydrophobicContact CG-CB 4.39Å; D245-A247 PolarHBondContact OD1-N 3.47Å; A247-S249 PolarHBondContact O-N 3.03Å; A247-S249 VanDerWaalsContact O-N 3.08Å; A247-E250 HydrophobicContact CB-CG 4.24Å; A247-E250 WeakPolarHBondContact O-CB 3.37Å; A247-E250 PolarHBondContact O-N 3.41Å
248A98.3Very high98Very high0 Ų033.6 Ų33.60%018%0.183CC..G310 helixtrans-61.5-23.8-168.200000115V246 E250 F251 F252 Y257 D294 P295V246-A248 VanDerWaalsContact C-N 3.31Å; V246-A248 HydrophobicContact CG1-CB 4.15Å; V246-A248 PolarHBondContact O-N 3.42Å; A248-E250 PolarHBondContact O-N 3.28Å; A248-F251 HydrophobicContact CB-CE1 4.44Å; A248-F251 HydrophobicContact CB-CE2 3.97Å; A248-F251 HydrophobicContact CB-CZ 3.82Å; A248-F251 CarbonylContact O-C 3.54Å; A248-F251 PolarHBondContact O-N 2.96Å; A248-F252 PolarHBondContact O-N 3.3Å; A248-Y257 HydrophobicContact CB-CD1 4.1Å; A248-Y257 HydrophobicContact CB-CE1 3.81Å; A248-D294 WeakPolarHBondContact CB-O 3.4Å; A248-D294 PolarHBondContact N-O 2.93Å; A248-D294 VanDerWaalsContact N-O 3.11Å; A248-P295 WeakPolarHBondContact CB-O 3.22Å
249S97.9Very high97.9Very high15 Ų1528.5 Ų28.511%0.10516%0.156CC..G310 helixtrans-55-34.8173.2-51.70000112.2A247 F251 F252 Q298A247-S249 PolarHBondContact O-N 3.03Å; A247-S249 VanDerWaalsContact O-N 3.08Å; S249-F251 PolarHBondContact O-N 3.25Å; S249-F252 PolarHBondContact O-N 3.01Å; S249-Q298 PolarHBondContact OG-N 3.12Å; S249-Q298 VanDerWaalsContact OG-N 3.1Å
250E96.4Very high97.8Very high54 Ų5426.4 Ų26.425%0.25215%0.148SC..G310 helixtrans-64.4-28.6-177.8-65.7-68.596.300112.6S157 A247 A248 R253 F261S157-E250 PolarHBondContact OG-OE2 2.71Å; A247-E250 HydrophobicContact CB-CG 4.24Å; A247-E250 WeakPolarHBondContact O-CB 3.37Å; A247-E250 PolarHBondContact O-N 3.41Å; A248-E250 PolarHBondContact O-N 3.28Å; E250-R253 PolarHBondContact O-NH1 3.47Å; E250-R253 PolarHBondContact O-NH2 2.82Å; E250-F261 HydrophobicContact CB-CZ 4.49Å
251F97.3Very high97.7Very high0 Ų028.1 Ų28.10%016%0.155CC..G310 helixtrans-119.814.9-178.859.1-104.1000113.9A164 V246 A248 S249 R253 Y257 D258 L259 F261 L276A164-F251 HydrophobicContact CB-CD1 4.35Å; A164-F251 HydrophobicContact CB-CE1 4.42Å; V246-F251 HydrophobicContact CG1-CE1 3.94Å; V246-F251 HydrophobicContact CG1-CZ 3.45Å; V246-F251 VanDerWaalsContact CG1-CZ 3.45Å; V246-F251 WeakPolarHBondContact O-CE1 3.42Å; A248-F251 HydrophobicContact CB-CE1 4.44Å; A248-F251 HydrophobicContact CB-CE2 3.97Å; A248-F251 HydrophobicContact CB-CZ 3.82Å; A248-F251 CarbonylContact O-C 3.54Å; A248-F251 PolarHBondContact O-N 2.96Å; S249-F251 PolarHBondContact O-N 3.25Å; F251-R253 PolarHBondContact O-N 3.34Å; F251-Y257 AromaticContact CD2-CD1 3.86Å; F251-Y257 HydrophobicContact CD2-CD1 3.86Å; F251-Y257 HydrophobicContact CD2-CG 4.37Å; F251-Y257 AromaticContact CE2-CD1 3.72Å; F251-Y257 HydrophobicContact CE2-CD1 3.72Å; F251-Y257 HydrophobicContact CE2-CG 4.22Å; F251-Y257 WeakPolarHBondContact O-CA 3.44Å; F251-D258 VanDerWaalsContact CB-O 3.26Å; F251-D258 WeakPolarHBondContact CB-O 3.44Å; F251-D258 PolarHBondContact O-N 3.41Å; F251-L259 HydrophobicContact CD2-CD2 4.39Å; F251-L259 HydrophobicContact CE2-CD2 3.84Å; F251-L259 HydrophobicContact CZ-CD2 4.09Å; F251-F261 HydrophobicContact CB-CB 3.73Å; F251-F261 HydrophobicContact CB-CD1 3.55Å; F251-F261 HydrophobicContact CB-CD2 4.5Å; F251-F261 HydrophobicContact CB-CE1 4.24Å; F251-F261 HydrophobicContact CB-CG 3.68Å; F251-F261 HydrophobicContact CD1-CD1 4.2Å; F251-F261 HydrophobicContact CD1-CE1 4.19Å; F251-F261 HydrophobicContact CG-CD1 4.27Å; F251-L276 HydrophobicContact CE2-CD2 4.34Å
252F98Very high97.5Very high56 Ų5630.2 Ų30.225%0.24616%0.162CC..EExtended strand (participates in β ladder)trans-72.9125.1169.1-176-116.1000110.4A248 S249 G255 K256 Y257 D297A248-F252 PolarHBondContact O-N 3.3Å; S249-F252 PolarHBondContact O-N 3.01Å; F252-G255 VanDerWaalsContact CZ-CA 3.44Å; F252-K256 CarbonylContact C-O 3.56Å; F252-K256 WeakPolarHBondContact CA-O 3.26Å; F252-K256 WeakPolarHBondContact CD2-O 3.45Å; F252-Y257 HydrophobicContact CB-CD1 4.28Å; F252-Y257 HydrophobicContact CB-CE1 4.08Å; F252-Y257 AromaticContact CD2-CD1 3.99Å; F252-Y257 HydrophobicContact CD2-CD1 3.99Å; F252-Y257 AromaticContact CD2-CE1 3.51Å; F252-Y257 HydrophobicContact CD2-CE1 3.51Å; F252-Y257 HydrophobicContact CD2-CE2 4.13Å; F252-Y257 HydrophobicContact CD2-CG 4.48Å; F252-Y257 AromaticContact CD2-CZ 3.57Å; F252-Y257 HydrophobicContact CE2-CE1 4.36Å; F252-Y257 HydrophobicContact CE2-CE2 4.31Å; F252-Y257 AromaticContact CE2-CZ 3.96Å; F252-Y257 HydrophobicContact CG-CE1 4.22Å; F252-D297 HydrophobicContact CB-CB 3.82Å; F252-D297 HydrophobicContact CD1-CB 3.76Å; F252-D297 VanDerWaalsContact CD1-CG 3.47Å; F252-D297 HydrophobicContact CD2-CB 3.8Å; F252-D297 HydrophobicContact CE1-CB 4.18Å; F252-D297 HydrophobicContact CE2-CB 4.2Å; F252-D297 HydrophobicContact CG-CB 3.53Å; F252-D297 HydrophobicContact CZ-CB 4.37Å
253R97.1Very high97.3Very high82 Ų8231.1 Ų31.131%0.30917%0.168SC..EExtended strand (participates in β ladder)trans-138.8115.6-176.5-60.7-65.2179-86.7-5.7109.1E250 F251 G255 K256 D258 Y270E250-R253 PolarHBondContact O-NH1 3.47Å; E250-R253 PolarHBondContact O-NH2 2.82Å; F251-R253 PolarHBondContact O-N 3.34Å; R253-G255 VanDerWaalsContact C-N 3.31Å; R253-G255 PolarHBondContact O-N 3.42Å; R253-K256 PolarHBondContact N-O 3.23Å; R253-K256 CarbonylContact O-C 3.55Å; R253-K256 WeakPolarHBondContact O-CA 3.48Å; R253-K256 PolarHBondContact O-N 3.12Å; R253-D258 HydrophobicContact CG-CB 4.27Å; R253-Y270 HydrophobicContact CB-CD2 4.06Å; R253-Y270 HydrophobicContact CB-CE1 4.41Å; R253-Y270 HydrophobicContact CB-CE2 3.36Å; R253-Y270 HydrophobicContact CG-CE1 4.47Å; R253-Y270 HydrophobicContact CG-CE2 4.21Å
254S93.9Very high97.2Very high123 Ų12336.7 Ų36.786%0.8620%0.204SC*.THydrogen-bonded Turntrans51.243.5171.5-55.40000114.5K256S254-K256 VanDerWaalsContact C-N 3.32Å
255G96.9Very high97Very high40 Ų4041.8 Ų41.841%0.41223%0.232SC..THydrogen-bonded Turntrans81.66.6-179.700000115.1F252 R253F252-G255 VanDerWaalsContact CZ-CA 3.44Å; R253-G255 VanDerWaalsContact C-N 3.31Å; R253-G255 PolarHBondContact O-N 3.42Å
256K98.5Very high96.9Very high93 Ų9345 Ų4540%0.40425%0.249SC..EExtended strand (participates in β ladder)trans-133.5179.9179.6-64.9-172.3178.2-175.30110.6F252 R253 S254 Y270 I271F252-K256 CarbonylContact C-O 3.56Å; F252-K256 WeakPolarHBondContact CA-O 3.26Å; F252-K256 WeakPolarHBondContact CD2-O 3.45Å; R253-K256 PolarHBondContact N-O 3.23Å; R253-K256 CarbonylContact O-C 3.55Å; R253-K256 WeakPolarHBondContact O-CA 3.48Å; R253-K256 PolarHBondContact O-N 3.12Å; S254-K256 VanDerWaalsContact C-N 3.32Å; K256-Y270 HydrophobicContact CB-CD2 4.22Å; K256-Y270 HydrophobicContact CB-CG 4.45Å; K256-I271 WeakPolarHBondContact CA-O 3.4Å; K256-I271 WeakPolarHBondContact CB-O 3.37Å
257Y98.6Very high96.8Very high0 Ų048.9 Ų48.90%027%0.274CS..EExtended strand (participates in β ladder)trans-125.4133.8-176.4-62.4-85.5000111.8A248 F251 F252 Y270 I271 P273 L276 F296 D297 D300A248-Y257 HydrophobicContact CB-CD1 4.1Å; A248-Y257 HydrophobicContact CB-CE1 3.81Å; F251-Y257 AromaticContact CD2-CD1 3.86Å; F251-Y257 HydrophobicContact CD2-CD1 3.86Å; F251-Y257 HydrophobicContact CD2-CG 4.37Å; F251-Y257 AromaticContact CE2-CD1 3.72Å; F251-Y257 HydrophobicContact CE2-CD1 3.72Å; F251-Y257 HydrophobicContact CE2-CG 4.22Å; F251-Y257 WeakPolarHBondContact O-CA 3.44Å; F252-Y257 HydrophobicContact CB-CD1 4.28Å; F252-Y257 HydrophobicContact CB-CE1 4.08Å; F252-Y257 AromaticContact CD2-CD1 3.99Å; F252-Y257 HydrophobicContact CD2-CD1 3.99Å; F252-Y257 AromaticContact CD2-CE1 3.51Å; F252-Y257 HydrophobicContact CD2-CE1 3.51Å; F252-Y257 HydrophobicContact CD2-CE2 4.13Å; F252-Y257 HydrophobicContact CD2-CG 4.48Å; F252-Y257 AromaticContact CD2-CZ 3.57Å; F252-Y257 HydrophobicContact CE2-CE1 4.36Å; F252-Y257 HydrophobicContact CE2-CE2 4.31Å; F252-Y257 AromaticContact CE2-CZ 3.96Å; F252-Y257 HydrophobicContact CG-CE1 4.22Å; Y257-Y270 WeakPolarHBondContact O-CA 3.14Å; Y257-I271 PolarHBondContact N-O 3.41Å; Y257-I271 PolarHBondContact O-N 2.9Å; Y257-P273 HydrophobicContact CE2-CB 3.98Å; Y257-P273 HydrophobicContact CE2-CG 3.89Å; Y257-L276 HydrophobicContact CD1-CD2 3.74Å; Y257-L276 HydrophobicContact CD2-CB 4.41Å; Y257-L276 HydrophobicContact CD2-CD2 3.57Å; Y257-L276 HydrophobicContact CE1-CD2 4.17Å; Y257-L276 HydrophobicContact CE2-CD2 4.03Å; Y257-L276 HydrophobicContact CG-CD2 3.42Å; Y257-L276 VanDerWaalsContact CG-CD2 3.42Å; Y257-F296 HydrophobicContact CE2-CD1 4.03Å; Y257-F296 AromaticContact CZ-CD1 3.91Å; Y257-F296 WeakPolarHBondContact OH-CA 3.42Å; Y257-F296 VanDerWaalsContact OH-CB 3.31Å; Y257-F296 WeakPolarHBondContact OH-CB 3.42Å; Y257-D297 HydrophobicContact CE1-CB 4.28Å; Y257-D297 PolarHBondContact OH-N 3.47Å; Y257-D300 WeakPolarHBondContact OH-CB 3.48Å; Y257-D300 PolarHBondContact OH-OD2 2.97Å
258D98.2Very high96.8Very high2 Ų253.6 Ų53.61%0.01131%0.307CS..  trans-10598.5179-174.32000112.2F251 R253 D260 F261 R269 Y270F251-D258 VanDerWaalsContact CB-O 3.26Å; F251-D258 WeakPolarHBondContact CB-O 3.44Å; F251-D258 PolarHBondContact O-N 3.41Å; R253-D258 HydrophobicContact CG-CB 4.27Å; D258-D260 PolarHBondContact O-N 2.84Å; D258-D260 PolarHBondContact OD1-N 3.24Å; D258-F261 HydrophobicContact CB-CB 4.11Å; D258-F261 PolarHBondContact O-N 2.62Å; D258-F261 PolarHBondContact OD1-N 3.12Å; D258-F261 WeakPolarHBondContact OD2-CA 3.37Å; D258-R269 WeakPolarHBondContact OD1-CD 3.37Å; D258-R269 IonicContact OD1-CZ 3.42Å; D258-R269 IonicContact OD1-NE 2.69Å; D258-R269 PolarHBondContact OD1-NE 3.48Å; D258-R269 IonicContact OD1-NH2 3.48Å; D258-R269 PolarHBondContact OD1-NH2 3.33Å; D258-R269 IonicContact OD2-CZ 3.45Å; D258-R269 IonicContact OD2-NE 3.34Å; D258-R269 PolarHBondContact OD2-NE 2.8Å; D258-R269 IonicContact OD2-NH2 2.74Å; D258-R269 PolarHBondContact OD2-NH2 2.82Å; D258-Y270 HydrophobicContact CB-CD1 3.69Å; D258-Y270 HydrophobicContact CB-CE1 3.6Å; D258-Y270 WeakPolarHBondContact OD2-CE1 3.45Å
259L97.7Very high96.7Very high37 Ų3756.7 Ų56.719%0.19432%0.319CS..THydrogen-bonded Turntrans-73.45.6179.4-60-175.9000114.7A164 M165 F251 I271 L276 L279A164-L259 HydrophobicContact CB-CB 4.42Å; A164-L259 HydrophobicContact CB-CD2 4.43Å; A164-L259 VanDerWaalsContact CB-O 3.23Å; A164-L259 WeakPolarHBondContact CB-O 3.35Å; M165-L259 HydrophobicContact CE-CD2 4.5Å; F251-L259 HydrophobicContact CD2-CD2 4.39Å; F251-L259 HydrophobicContact CE2-CD2 3.84Å; F251-L259 HydrophobicContact CZ-CD2 4.09Å; L259-I271 HydrophobicContact CD1-CD1 3.57Å; L259-I271 HydrophobicContact CG-CD1 3.92Å; L259-I271 HydrophobicContact CG-CG1 4.49Å; L259-L276 HydrophobicContact CD2-CD1 4.21Å; L259-L279 HydrophobicContact CD1-CD2 3.69Å
260D96.8Very high96.7Very high23 Ų2357 Ų5712%0.12332%0.318CS..THydrogen-bonded Turntrans-133.934.5171.9-173.327.7000110.9L218 D258 K262 S263 R269L218-D260 HydrophobicContact CD1-CB 3.83Å; L218-D260 WeakPolarHBondContact CD1-OD1 3.31Å; D258-D260 PolarHBondContact O-N 2.84Å; D258-D260 PolarHBondContact OD1-N 3.24Å; D260-K262 PolarHBondContact O-N 3.23Å; D260-S263 VanDerWaalsContact CG-CB 3.45Å; D260-S263 WeakPolarHBondContact O-CB 3.24Å; D260-S263 PolarHBondContact O-N 2.85Å; D260-S263 VanDerWaalsContact OD1-CB 3.3Å; D260-S263 WeakPolarHBondContact OD1-CB 3.32Å; D260-S263 PolarHBondContact OD1-OG 2.8Å; D260-S263 VanDerWaalsContact OD2-CB 3.22Å; D260-S263 WeakPolarHBondContact OD2-CB 3.47Å; D260-S263 PolarHBondContact OD2-OG 2.83Å; D260-S263 VanDerWaalsContact OD2-OG 3.07Å; D260-R269 VanDerWaalsContact O-CZ 3.29Å; D260-R269 PolarHBondContact O-NH1 3.48Å; D260-R269 PolarHBondContact O-NH2 2.77Å; D260-R269 IonicContact OD2-CZ 3.81Å; D260-R269 IonicContact OD2-NH1 2.95Å; D260-R269 PolarHBondContact OD2-NH1 3.47Å
261F96.3Very high96.8Very high37 Ų3756 Ų5616%0.16231%0.314CS..THydrogen-bonded Turntrans-57.3-14.1-17580.6-83.3000116.1A164 E250 F251 D258A164-F261 HydrophobicContact CB-CD1 4.04Å; A164-F261 HydrophobicContact CB-CE1 4.16Å; E250-F261 HydrophobicContact CB-CZ 4.49Å; F251-F261 HydrophobicContact CB-CB 3.73Å; F251-F261 HydrophobicContact CB-CD1 3.55Å; F251-F261 HydrophobicContact CB-CD2 4.5Å; F251-F261 HydrophobicContact CB-CE1 4.24Å; F251-F261 HydrophobicContact CB-CG 3.68Å; F251-F261 HydrophobicContact CD1-CD1 4.2Å; F251-F261 HydrophobicContact CD1-CE1 4.19Å; F251-F261 HydrophobicContact CG-CD1 4.27Å; D258-F261 HydrophobicContact CB-CB 4.11Å; D258-F261 PolarHBondContact O-N 2.62Å; D258-F261 PolarHBondContact OD1-N 3.12Å; D258-F261 WeakPolarHBondContact OD2-CA 3.37Å
262K94.6Very high96.9Very high69 Ų6957.6 Ų57.630%0.333%0.325SS..THydrogen-bonded Turntrans-86.4-12.6176.2-69-176-78-174.80113.2G156 A159 N161 L163 D260G156-K262 WeakPolarHBondContact O-CD 3.46Å; G156-K262 PolarHBondContact O-NZ 3.21Å; A159-K262 PolarHBondContact O-NZ 2.83Å; N161-K262 VanDerWaalsContact O-CD 3.3Å; N161-K262 WeakPolarHBondContact O-CD 3.46Å; N161-K262 WeakPolarHBondContact O-CE 3.48Å; N161-K262 PolarHBondContact O-NZ 3.05Å; N161-K262 PolarHBondContact OD1-NZ 2.76Å; L163-K262 WeakPolarHBondContact O-CE 3.4Å; L163-K262 PolarHBondContact O-NZ 2.78Å; D260-K262 PolarHBondContact O-N 3.23Å
263S94.7Very high96.9Very high19 Ų1956.2 Ų56.213%0.13332%0.322CS..SBendtrans-89.2164.6168.6-64.70000110.1K162 D260 D265 R269K162-S263 PolarHBondContact NZ-OG 2.94Å; D260-S263 VanDerWaalsContact CG-CB 3.45Å; D260-S263 WeakPolarHBondContact O-CB 3.24Å; D260-S263 PolarHBondContact O-N 2.85Å; D260-S263 VanDerWaalsContact OD1-CB 3.3Å; D260-S263 WeakPolarHBondContact OD1-CB 3.32Å; D260-S263 PolarHBondContact OD1-OG 2.8Å; D260-S263 VanDerWaalsContact OD2-CB 3.22Å; D260-S263 WeakPolarHBondContact OD2-CB 3.47Å; D260-S263 PolarHBondContact OD2-OG 2.83Å; D260-S263 VanDerWaalsContact OD2-OG 3.07Å; S263-D265 PolarHBondContact O-N 3.09Å; S263-R269 PolarHBondContact O-NH2 3.35Å
264P95.6Very high96.9Very high117 Ų11756.3 Ų56.376%0.7633%0.328SS*.SBendtrans-47.8141.9173.3-28.536.1000112.1R269P264-R269 PolarHBondContact O-NH1 3.34Å; P264-R269 PolarHBondContact O-NH2 2.96Å
265D95.8Very high97.2Very high108 Ų10855.6 Ų55.658%0.57831%0.311SS*.PPolyproline II helixtrans-64.9133.4-171.5-170.237.2000112.4S263 Y270S263-D265 PolarHBondContact O-N 3.09Å; D265-Y270 VanDerWaalsContact CG-OH 3.23Å; D265-Y270 PolarHBondContact OD1-OH 3.32Å; D265-Y270 PolarHBondContact OD2-OH 2.88Å
266D96.5Very high97.3Very high68 Ų6853.7 Ų53.736%0.36429%0.292SS..  trans-145.199.9178.5-178.8-3.6000110.3S268 R269 Y270D266-S268 VanDerWaalsContact CG-OG 3.24Å; D266-S268 PolarHBondContact O-N 2.81Å; D266-S268 VanDerWaalsContact OD1-CB 3.26Å; D266-S268 WeakPolarHBondContact OD1-CB 3.5Å; D266-S268 PolarHBondContact OD1-N 2.55Å; D266-S268 PolarHBondContact OD1-OG 3.25Å; D266-S268 PolarHBondContact OD2-OG 3.46Å; D266-R269 HydrophobicContact CB-CG 4.09Å; D266-R269 WeakPolarHBondContact O-CG 3.4Å; D266-R269 PolarHBondContact O-N 2.97Å; D266-Y270 WeakPolarHBondContact O-CD1 3.43Å; D266-Y270 VanDerWaalsContact O-CE1 3.32Å; D266-Y270 WeakPolarHBondContact O-CE1 3.31Å
267P96.5Very high97.3Very high82 Ų8249.6 Ų49.653%0.53228%0.276SS..G310 helixtrans-62-15.5179.9-26.736.1000115.2Y270P267-Y270 HydrophobicContact CB-CD2 4.24Å; P267-Y270 HydrophobicContact CB-CE2 4.06Å; P267-Y270 HydrophobicContact CG-CE2 4.38Å; P267-Y270 PolarHBondContact O-N 2.87Å
268S96.9Very high97.3Very high101 Ų10154 Ų5471%0.70630%0.299SS*.G310 helixtrans-74.5-24.7-179.176.20000113.3D266D266-S268 VanDerWaalsContact CG-OG 3.24Å; D266-S268 PolarHBondContact O-N 2.81Å; D266-S268 VanDerWaalsContact OD1-CB 3.26Å; D266-S268 WeakPolarHBondContact OD1-CB 3.5Å; D266-S268 PolarHBondContact OD1-N 2.55Å; D266-S268 PolarHBondContact OD1-OG 3.25Å; D266-S268 PolarHBondContact OD2-OG 3.46Å
269R96.1Very high97.3Very high64 Ų6456.2 Ų56.224%0.24231%0.311CS..G310 helixtrans-86.6-6.6175.160.7168.4-168.8-133.2-10.9113.8D258 D260 S263 P264 D266 I271D258-R269 WeakPolarHBondContact OD1-CD 3.37Å; D258-R269 IonicContact OD1-CZ 3.42Å; D258-R269 IonicContact OD1-NE 2.69Å; D258-R269 PolarHBondContact OD1-NE 3.48Å; D258-R269 IonicContact OD1-NH2 3.48Å; D258-R269 PolarHBondContact OD1-NH2 3.33Å; D258-R269 IonicContact OD2-CZ 3.45Å; D258-R269 IonicContact OD2-NE 3.34Å; D258-R269 PolarHBondContact OD2-NE 2.8Å; D258-R269 IonicContact OD2-NH2 2.74Å; D258-R269 PolarHBondContact OD2-NH2 2.82Å; D260-R269 VanDerWaalsContact O-CZ 3.29Å; D260-R269 PolarHBondContact O-NH1 3.48Å; D260-R269 PolarHBondContact O-NH2 2.77Å; D260-R269 IonicContact OD2-CZ 3.81Å; D260-R269 IonicContact OD2-NH1 2.95Å; D260-R269 PolarHBondContact OD2-NH1 3.47Å; S263-R269 PolarHBondContact O-NH2 3.35Å; P264-R269 PolarHBondContact O-NH1 3.34Å; P264-R269 PolarHBondContact O-NH2 2.96Å; D266-R269 HydrophobicContact CB-CG 4.09Å; D266-R269 WeakPolarHBondContact O-CG 3.4Å; D266-R269 PolarHBondContact O-N 2.97Å; R269-I271 PolarHBondContact O-N 3.37Å
270Y98.2Very high97.3Very high22 Ų2254.5 Ų54.59%0.08630%0.301CS..PPolyproline II helixtrans-67.2132.4-178.4-66.21.5000111.4R253 K256 Y257 D258 D265 D266 P267R253-Y270 HydrophobicContact CB-CD2 4.06Å; R253-Y270 HydrophobicContact CB-CE1 4.41Å; R253-Y270 HydrophobicContact CB-CE2 3.36Å; R253-Y270 HydrophobicContact CG-CE1 4.47Å; R253-Y270 HydrophobicContact CG-CE2 4.21Å; K256-Y270 HydrophobicContact CB-CD2 4.22Å; K256-Y270 HydrophobicContact CB-CG 4.45Å; Y257-Y270 WeakPolarHBondContact O-CA 3.14Å; D258-Y270 HydrophobicContact CB-CD1 3.69Å; D258-Y270 HydrophobicContact CB-CE1 3.6Å; D258-Y270 WeakPolarHBondContact OD2-CE1 3.45Å; D265-Y270 VanDerWaalsContact CG-OH 3.23Å; D265-Y270 PolarHBondContact OD1-OH 3.32Å; D265-Y270 PolarHBondContact OD2-OH 2.88Å; D266-Y270 WeakPolarHBondContact O-CD1 3.43Å; D266-Y270 VanDerWaalsContact O-CE1 3.32Å; D266-Y270 WeakPolarHBondContact O-CE1 3.31Å; P267-Y270 HydrophobicContact CB-CD2 4.24Å; P267-Y270 HydrophobicContact CB-CE2 4.06Å; P267-Y270 HydrophobicContact CG-CE2 4.38Å; P267-Y270 PolarHBondContact O-N 2.87Å
271I98.6Very high97.4Very high33 Ų3357.4 Ų57.417%0.16931%0.313CS..BIsolated β-bridgetrans-103.5149.6178.963.5171.9000111.4K256 Y257 L259 R269 Q275 L276K256-I271 WeakPolarHBondContact CA-O 3.4Å; K256-I271 WeakPolarHBondContact CB-O 3.37Å; Y257-I271 PolarHBondContact N-O 3.41Å; Y257-I271 PolarHBondContact O-N 2.9Å; L259-I271 HydrophobicContact CD1-CD1 3.57Å; L259-I271 HydrophobicContact CG-CD1 3.92Å; L259-I271 HydrophobicContact CG-CG1 4.49Å; R269-I271 PolarHBondContact O-N 3.37Å; I271-Q275 HydrophobicContact CB-CB 3.99Å; I271-L276 HydrophobicContact CD1-CB 3.88Å; I271-L276 HydrophobicContact CD1-CD1 3.99Å; I271-L276 HydrophobicContact CD1-CG 4.48Å; I271-L276 HydrophobicContact CG1-CB 4.41Å
272S98.6Very high97.5Very high33 Ų3357.5 Ų57.523%0.23132%0.318CS..PPolyproline II helixtrans-72.2162.917776.10000111.9D274 Q275 L276S272-D274 PolarHBondContact O-N 3.36Å; S272-D274 PolarHBondContact OG-N 3.01Å; S272-Q275 PolarHBondContact O-N 3.44Å; S272-Q275 WeakPolarHBondContact OG-CG 3.42Å; S272-Q275 PolarHBondContact OG-N 2.95Å; S272-Q275 VanDerWaalsContact OG-N 3.15Å; S272-Q275 PolarHBondContact OG-OE1 3.33Å; S272-L276 PolarHBondContact O-N 2.93Å
273P98.6Very high97.7Very high28 Ų2854.3 Ų54.318%0.18230%0.304CS..Hα-helixtrans-55.6-39.1172.3-19.726.7000112.9Y257 L276 A277 F296 D300 A303Y257-P273 HydrophobicContact CE2-CB 3.98Å; Y257-P273 HydrophobicContact CE2-CG 3.89Å; P273-L276 PolarHBondContact O-N 3.23Å; P273-A277 WeakPolarHBondContact O-CB 3.37Å; P273-A277 PolarHBondContact O-N 2.81Å; P273-F296 HydrophobicContact CB-CD1 4.38Å; P273-F296 HydrophobicContact CB-CE1 4.35Å; P273-F296 WeakPolarHBondContact O-CE1 3.46Å; P273-D300 WeakPolarHBondContact CG-OD2 3.22Å; P273-A303 HydrophobicContact CB-CB 3.71Å
274D98.4Very high97.9Very high83 Ų8355.3 Ų55.344%0.44431%0.308SS..Hα-helixtrans-67.8-39.7178.8-66.3-29.9000111.5S272 A277 D278 K306S272-D274 PolarHBondContact O-N 3.36Å; S272-D274 PolarHBondContact OG-N 3.01Å; D274-A277 WeakPolarHBondContact O-CB 3.4Å; D274-A277 PolarHBondContact O-N 3.04Å; D274-D278 PolarHBondContact O-N 3.33Å; D274-K306 IonicContact OD1-NZ 2.63Å; D274-K306 PolarHBondContact OD1-NZ 2.85Å; D274-K306 IonicContact OD2-NZ 3.87Å
275Q98.7Very high98Very high108 Ų10858 Ų5851%0.50531%0.308SS..Hα-helixtrans-64.2-39.9174.7-73.4174.2-53.700112I271 S272 D278 L279I271-Q275 HydrophobicContact CB-CB 3.99Å; S272-Q275 PolarHBondContact O-N 3.44Å; S272-Q275 WeakPolarHBondContact OG-CG 3.42Å; S272-Q275 PolarHBondContact OG-N 2.95Å; S272-Q275 VanDerWaalsContact OG-N 3.15Å; S272-Q275 PolarHBondContact OG-OE1 3.33Å; Q275-D278 PolarHBondContact O-N 2.82Å; Q275-L279 PolarHBondContact O-N 3.38Å
276L98.7Very high98.1Very high0 Ų056.1 Ų56.10%030%0.298CS..Hα-helixtrans-66.9-40.8175.9-177.756.4000111.5M165 F251 Y257 L259 I271 S272 P273 D278 L279 Y280 F296M165-L276 HydrophobicContact CE-CD1 4.45Å; F251-L276 HydrophobicContact CE2-CD2 4.34Å; Y257-L276 HydrophobicContact CD1-CD2 3.74Å; Y257-L276 HydrophobicContact CD2-CB 4.41Å; Y257-L276 HydrophobicContact CD2-CD2 3.57Å; Y257-L276 HydrophobicContact CE1-CD2 4.17Å; Y257-L276 HydrophobicContact CE2-CD2 4.03Å; Y257-L276 HydrophobicContact CG-CD2 3.42Å; Y257-L276 VanDerWaalsContact CG-CD2 3.42Å; L259-L276 HydrophobicContact CD2-CD1 4.21Å; I271-L276 HydrophobicContact CD1-CB 3.88Å; I271-L276 HydrophobicContact CD1-CD1 3.99Å; I271-L276 HydrophobicContact CD1-CG 4.48Å; I271-L276 HydrophobicContact CG1-CB 4.41Å; S272-L276 PolarHBondContact O-N 2.93Å; P273-L276 PolarHBondContact O-N 3.23Å; L276-D278 VanDerWaalsContact C-N 3.33Å; L276-D278 PolarHBondContact O-N 3.24Å; L276-L279 HydrophobicContact CD1-CD2 4.31Å; L276-L279 WeakPolarHBondContact O-CB 3.43Å; L276-L279 PolarHBondContact O-N 2.93Å; L276-Y280 HydrophobicContact CD1-CE1 3.8Å; L276-Y280 HydrophobicContact CD1-CE2 3.99Å; L276-Y280 VanDerWaalsContact CD1-CZ 3.44Å; L276-Y280 WeakPolarHBondContact CD1-OH 3.43Å; L276-Y280 HydrophobicContact CD2-CE2 4.19Å; L276-Y280 WeakPolarHBondContact CD2-OH 3.46Å; L276-Y280 HydrophobicContact CG-CD2 4.41Å; L276-Y280 HydrophobicContact CG-CE1 4.31Å; L276-Y280 HydrophobicContact CG-CE2 3.55Å; L276-Y280 VanDerWaalsContact CG-CZ 3.48Å; L276-Y280 WeakPolarHBondContact CG-OH 3.27Å; L276-Y280 VanDerWaalsContact O-CD2 3.29Å; L276-Y280 WeakPolarHBondContact O-CD2 3.3Å; L276-Y280 PolarHBondContact O-N 2.98Å; L276-F296 HydrophobicContact CB-CE1 4.35Å; L276-F296 HydrophobicContact CD2-CD1 4.27Å; L276-F296 HydrophobicContact CD2-CE1 4.29Å; L276-F296 HydrophobicContact CG-CE1 4.31Å
277A98.7Very high98.2Very high8 Ų853.3 Ų53.37%0.06628%0.282CS..Hα-helixtrans-59.4-42.2173.500000112.3P273 D274 L279 Y280 K281 F296 F307P273-A277 WeakPolarHBondContact O-CB 3.37Å; P273-A277 PolarHBondContact O-N 2.81Å; D274-A277 WeakPolarHBondContact O-CB 3.4Å; D274-A277 PolarHBondContact O-N 3.04Å; A277-L279 VanDerWaalsContact C-N 3.34Å; A277-Y280 PolarHBondContact O-N 2.78Å; A277-K281 WeakPolarHBondContact O-CG 3.44Å; A277-K281 PolarHBondContact O-N 2.98Å; A277-F296 HydrophobicContact CB-CE1 4.42Å; A277-F296 HydrophobicContact CB-CZ 3.88Å; A277-F307 HydrophobicContact CB-CD2 4.12Å
278D98.6Very high98.3Very high92 Ų9252.2 Ų52.249%0.49228%0.275SS..Hα-helixtrans-68-34177.5-72.1-17.6000112.4D274 Q275 L276 K281 S282D274-D278 PolarHBondContact O-N 3.33Å; Q275-D278 PolarHBondContact O-N 2.82Å; L276-D278 VanDerWaalsContact C-N 3.33Å; L276-D278 PolarHBondContact O-N 3.24Å; D278-K281 PolarHBondContact O-N 3.36Å; D278-K281 IonicContact OD1-NZ 3.67Å; D278-K281 PolarHBondContact OD1-NZ 3.09Å; D278-S282 PolarHBondContact O-N 3.43Å
279L98.6Very high98.4Very high49 Ų4947.6 Ų47.626%0.25724%0.242SC..Hα-helixtrans-60.2-47.8170.2-177.564000111M165 L259 Q275 L276 A277 K281 S282 F283M165-L279 HydrophobicContact CE-CD2 4.21Å; L259-L279 HydrophobicContact CD1-CD2 3.69Å; Q275-L279 PolarHBondContact O-N 3.38Å; L276-L279 HydrophobicContact CD1-CD2 4.31Å; L276-L279 WeakPolarHBondContact O-CB 3.43Å; L276-L279 PolarHBondContact O-N 2.93Å; A277-L279 VanDerWaalsContact C-N 3.34Å; L279-K281 PolarHBondContact O-N 3.12Å; L279-S282 WeakPolarHBondContact O-CB 3.2Å; L279-S282 PolarHBondContact O-N 2.93Å; L279-S282 VanDerWaalsContact O-N 3.12Å; L279-S282 PolarHBondContact O-OG 2.8Å; L279-F283 HydrophobicContact CD1-CD1 4.48Å; L279-F283 HydrophobicContact CD1-CE1 3.59Å; L279-F283 HydrophobicContact CD1-CE2 4.45Å; L279-F283 HydrophobicContact CD1-CZ 3.57Å; L279-F283 HydrophobicContact CD2-CE2 4.35Å; L279-F283 HydrophobicContact CD2-CZ 3.99Å; L279-F283 HydrophobicContact CG-CE1 4.01Å; L279-F283 HydrophobicContact CG-CE2 3.98Å; L279-F283 HydrophobicContact CG-CZ 3.57Å; L279-F283 PolarHBondContact O-N 3.12Å; L279-F283 VanDerWaalsContact O-N 3.1Å
280Y98.8Very high98.5Very high0 Ų046.4 Ų46.40%024%0.242CC..Hα-helixtrans-61.9-41.4176.5-58.7-40.2000113.2M165 V246 L276 A277 S282 F283 I284 I292 P295 F296 F307M165-Y280 HydrophobicContact CE-CD1 4.29Å; M165-Y280 HydrophobicContact CE-CE1 3.55Å; M165-Y280 HydrophobicContact SD-CE1 4.39Å; V246-Y280 HydrophobicContact CG1-CE1 4.22Å; V246-Y280 WeakPolarHBondContact CG1-OH 3.35Å; V246-Y280 HydrophobicContact CG2-CE1 3.81Å; L276-Y280 HydrophobicContact CD1-CE1 3.8Å; L276-Y280 HydrophobicContact CD1-CE2 3.99Å; L276-Y280 VanDerWaalsContact CD1-CZ 3.44Å; L276-Y280 WeakPolarHBondContact CD1-OH 3.43Å; L276-Y280 HydrophobicContact CD2-CE2 4.19Å; L276-Y280 WeakPolarHBondContact CD2-OH 3.46Å; L276-Y280 HydrophobicContact CG-CD2 4.41Å; L276-Y280 HydrophobicContact CG-CE1 4.31Å; L276-Y280 HydrophobicContact CG-CE2 3.55Å; L276-Y280 VanDerWaalsContact CG-CZ 3.48Å; L276-Y280 WeakPolarHBondContact CG-OH 3.27Å; L276-Y280 VanDerWaalsContact O-CD2 3.29Å; L276-Y280 WeakPolarHBondContact O-CD2 3.3Å; L276-Y280 PolarHBondContact O-N 2.98Å; A277-Y280 PolarHBondContact O-N 2.78Å; Y280-S282 PolarHBondContact O-N 3Å; Y280-F283 HydrophobicContact CD1-CD2 4.36Å; Y280-F283 WeakPolarHBondContact O-CA 3.31Å; Y280-F283 WeakPolarHBondContact O-CB 3.35Å; Y280-F283 PolarHBondContact O-N 3.47Å; Y280-I284 WeakPolarHBondContact O-CG1 3.06Å; Y280-I284 PolarHBondContact O-N 2.71Å; Y280-I292 HydrophobicContact CD1-CD1 4.39Å; Y280-I292 HydrophobicContact CG-CD1 4.29Å; Y280-P295 HydrophobicContact CD2-CB 3.97Å; Y280-P295 HydrophobicContact CE2-CB 3.4Å; Y280-P295 VanDerWaalsContact CE2-CB 3.4Å; Y280-P295 VanDerWaalsContact CE2-O 3.25Å; Y280-P295 WeakPolarHBondContact CE2-O 3.43Å; Y280-P295 PolarHBondContact OH-O 3.46Å; Y280-F296 HydrophobicContact CD2-CZ 4.28Å; Y280-F296 HydrophobicContact CE2-CE1 4.23Å; Y280-F296 HydrophobicContact CE2-CZ 4.03Å; Y280-F307 HydrophobicContact CD2-CD2 4.45Å; Y280-F307 HydrophobicContact CD2-CE1 4.41Å; Y280-F307 HydrophobicContact CD2-CE2 4.01Å; Y280-F307 AromaticContact CD2-CZ 3.99Å; Y280-F307 HydrophobicContact CD2-CZ 3.99Å; Y280-F307 HydrophobicContact CG-CE2 4.31Å; Y280-F307 HydrophobicContact CG-CZ 4.2Å
281K98.6Very high98.6Very high85 Ų8545.4 Ų45.437%0.3724%0.238SC..Hα-helixtrans-59.9-36.7174.7-69.3172-161.31550111.4A277 D278 L279 F283 I284 K285A277-K281 WeakPolarHBondContact O-CG 3.44Å; A277-K281 PolarHBondContact O-N 2.98Å; D278-K281 PolarHBondContact O-N 3.36Å; D278-K281 IonicContact OD1-NZ 3.67Å; D278-K281 PolarHBondContact OD1-NZ 3.09Å; L279-K281 PolarHBondContact O-N 3.12Å; K281-F283 VanDerWaalsContact C-N 3.31Å; K281-I284 PolarHBondContact O-N 3.46Å; K281-K285 WeakPolarHBondContact O-CB 3.44Å; K281-K285 PolarHBondContact O-N 2.96Å
282S98.4Very high98.6Very high38 Ų3843.9 Ų43.927%0.26623%0.23SC..Hα-helixtrans-63.7-38.2173.583.80000111.8D278 L279 Y280 K285 D286D278-S282 PolarHBondContact O-N 3.43Å; L279-S282 WeakPolarHBondContact O-CB 3.2Å; L279-S282 PolarHBondContact O-N 2.93Å; L279-S282 VanDerWaalsContact O-N 3.12Å; L279-S282 PolarHBondContact O-OG 2.8Å; Y280-S282 PolarHBondContact O-N 3Å; S282-K285 PolarHBondContact O-N 3.39Å; S282-D286 WeakPolarHBondContact O-CB 3.43Å; S282-D286 PolarHBondContact O-N 3.36Å
283F98.6Very high98.6Very high2 Ų242.3 Ų42.31%0.00922%0.22CC..Hα-helixtrans-67.5-43.3176.8-61.5-15000112.3M165 N220 K221 L224 M244 L279 Y280 K281 K285 D286 Y287M165-F283 HydrophobicContact CE-CE2 3.88Å; M165-F283 HydrophobicContact SD-CE2 4.03Å; N220-F283 HydrophobicContact CB-CE2 4.13Å; N220-F283 HydrophobicContact CB-CZ 3.96Å; K221-F283 HydrophobicContact CB-CE1 4.13Å; L224-F283 HydrophobicContact CD1-CB 3.77Å; L224-F283 HydrophobicContact CD1-CD1 3.76Å; L224-F283 HydrophobicContact CD1-CD2 3.78Å; L224-F283 HydrophobicContact CD1-CE1 4.27Å; L224-F283 HydrophobicContact CD1-CE2 4.27Å; L224-F283 HydrophobicContact CD1-CG 3.5Å; L224-F283 VanDerWaalsContact CD1-CG 3.5Å; M244-F283 HydrophobicContact CE-CD2 3.97Å; M244-F283 HydrophobicContact CE-CE2 4.1Å; M244-F283 HydrophobicContact SD-CD2 4.08Å; L279-F283 HydrophobicContact CD1-CD1 4.48Å; L279-F283 HydrophobicContact CD1-CE1 3.59Å; L279-F283 HydrophobicContact CD1-CE2 4.45Å; L279-F283 HydrophobicContact CD1-CZ 3.57Å; L279-F283 HydrophobicContact CD2-CE2 4.35Å; L279-F283 HydrophobicContact CD2-CZ 3.99Å; L279-F283 HydrophobicContact CG-CE1 4.01Å; L279-F283 HydrophobicContact CG-CE2 3.98Å; L279-F283 HydrophobicContact CG-CZ 3.57Å; L279-F283 PolarHBondContact O-N 3.12Å; L279-F283 VanDerWaalsContact O-N 3.1Å; Y280-F283 HydrophobicContact CD1-CD2 4.36Å; Y280-F283 WeakPolarHBondContact O-CA 3.31Å; Y280-F283 WeakPolarHBondContact O-CB 3.35Å; Y280-F283 PolarHBondContact O-N 3.47Å; K281-F283 VanDerWaalsContact C-N 3.31Å; F283-K285 PolarHBondContact O-N 2.97Å; F283-D286 PolarHBondContact O-N 3.35Å; F283-Y287 HydrophobicContact CB-CD2 4.43Å; F283-Y287 HydrophobicContact CD1-CE2 4.43Å; F283-Y287 WeakPolarHBondContact O-CB 3.34Å; F283-Y287 WeakPolarHBondContact O-CD2 3.5Å; F283-Y287 PolarHBondContact O-N 3.03Å
284I98.6Very high98.6Very high40 Ų4041 Ų4121%0.20521%0.211CC..Hα-helixtrans-62-34.8176.4-63.5164000111.2Y280 K281 V289 I292 F307 A311 I313Y280-I284 WeakPolarHBondContact O-CG1 3.06Å; Y280-I284 PolarHBondContact O-N 2.71Å; K281-I284 PolarHBondContact O-N 3.46Å; I284-V289 HydrophobicContact CG1-CB 4.49Å; I284-V289 HydrophobicContact CG1-CG1 4.38Å; I284-I292 HydrophobicContact CD1-CD1 4.18Å; I284-I292 HydrophobicContact CG1-CD1 4.22Å; I284-F307 HydrophobicContact CD1-CE2 4.47Å; I284-F307 HydrophobicContact CD1-CZ 4.13Å; I284-A311 HydrophobicContact CD1-CB 4.49Å; I284-I313 HydrophobicContact CD1-CD1 3.66Å; I284-I313 HydrophobicContact CD1-CG1 3.93Å; I284-I313 HydrophobicContact CG1-CD1 3.88Å; I284-I313 HydrophobicContact CG1-CG1 4.49Å; I284-I313 HydrophobicContact CG2-CG2 3.96Å
285K98.2Very high98.6Very high175 Ų17537.1 Ų37.176%0.76119%0.19SC*.Hα-helixtrans-73.5-43.8178.1-177.9-174.1173.4-171.80112.7K281 S282 F283K281-K285 WeakPolarHBondContact O-CB 3.44Å; K281-K285 PolarHBondContact O-N 2.96Å; S282-K285 PolarHBondContact O-N 3.39Å; F283-K285 PolarHBondContact O-N 2.97Å
286D98.1Very high98.6Very high68 Ų6832 Ų3236%0.36417%0.166SC..Hα-helixtrans-92.6-17.2-168-67.5-8.8000113.3K221 S282 F283K221-D286 IonicContact NZ-OD2 2.73Å; S282-D286 WeakPolarHBondContact O-CB 3.43Å; S282-D286 PolarHBondContact O-N 3.36Å; F283-D286 PolarHBondContact O-N 3.35Å
287Y98.6Very high98.6Very high9 Ų932.8 Ų32.84%0.03517%0.17CC..SBendtrans-134.8158.2-176-54.5-80.6000111.4K221 L224 E225 K228 F283 V289K221-Y287 WeakPolarHBondContact CE-OH 3.33Å; K221-Y287 HydrophobicContact CG-CE2 4.14Å; K221-Y287 WeakPolarHBondContact CG-OH 3.39Å; L224-Y287 HydrophobicContact CB-CD1 3.78Å; L224-Y287 HydrophobicContact CB-CD2 3.95Å; L224-Y287 HydrophobicContact CB-CE1 3.78Å; L224-Y287 HydrophobicContact CB-CE2 3.94Å; L224-Y287 HydrophobicContact CB-CG 3.89Å; L224-Y287 HydrophobicContact CD1-CD2 3.57Å; L224-Y287 HydrophobicContact CD1-CE2 3.83Å; L224-Y287 HydrophobicContact CD1-CG 4.13Å; L224-Y287 HydrophobicContact CG-CD2 4.33Å; L224-Y287 HydrophobicContact CG-CG 4.47Å; E225-Y287 VanDerWaalsContact CD-OH 3.27Å; E225-Y287 HydrophobicContact CG-CE1 4.11Å; E225-Y287 WeakPolarHBondContact CG-OH 3.02Å; E225-Y287 WeakPolarHBondContact OE1-CE1 3.23Å; E225-Y287 PolarHBondContact OE1-OH 2.7Å; K228-Y287 HydrophobicContact CB-CD1 4.48Å; K228-Y287 HydrophobicContact CD-CD1 4.1Å; K228-Y287 HydrophobicContact CD-CE1 4.13Å; F283-Y287 HydrophobicContact CB-CD2 4.43Å; F283-Y287 HydrophobicContact CD1-CE2 4.43Å; F283-Y287 WeakPolarHBondContact O-CB 3.34Å; F283-Y287 WeakPolarHBondContact O-CD2 3.5Å; F283-Y287 PolarHBondContact O-N 3.03Å; Y287-V289 PolarHBondContact O-N 3.02Å
288P98.1Very high98.6Very high58 Ų5833.2 Ų33.238%0.37717%0.171SC..  trans-76.249.5177.934.4-37.8000112.1V241 I242 V290V241-P288 WeakPolarHBondContact CB-O 2.83Å; V241-P288 HydrophobicContact CG1-CB 4.43Å; I242-P288 HydrophobicContact CD1-CG 4.22Å; I242-P288 HydrophobicContact CG1-CG 4.31Å; I242-P288 PolarHBondContact N-O 3.36Å; P288-V290 PolarHBondContact O-N 3.18Å
289V98.8Very high98.5Very high5 Ų531.7 Ų31.73%0.0316%0.163CC..EExtended strand (participates in β ladder)trans-77.6120.2177.3176.20000109.1L224 I242 M244 I284 Y287 I292 I313L224-V289 HydrophobicContact CD2-CG2 4.07Å; I242-V289 HydrophobicContact CB-CG2 4.1Å; I242-V289 HydrophobicContact CG2-CG2 3.95Å; I242-V289 WeakPolarHBondContact O-CA 3.34Å; M244-V289 HydrophobicContact SD-CG1 4.29Å; M244-V289 HydrophobicContact SD-CG2 4.16Å; I284-V289 HydrophobicContact CG1-CB 4.49Å; I284-V289 HydrophobicContact CG1-CG1 4.38Å; Y287-V289 PolarHBondContact O-N 3.02Å; V289-I292 HydrophobicContact CG1-CD1 3.99Å; V289-I292 HydrophobicContact CG1-CG1 3.71Å; V289-I313 HydrophobicContact CG1-CD1 4.28Å
290V98.8Very high98.5Very high38 Ų3830.9 Ų30.923%0.2316%0.159CC..EExtended strand (participates in β ladder)trans-120.1-7.5-177.2-59.60000113.6V241 I242 P288 I313 Q314 F428V241-V290 HydrophobicContact CB-CG1 3.89Å; V241-V290 HydrophobicContact CB-CG2 3.88Å; V241-V290 HydrophobicContact CG1-CG1 4.06Å; V241-V290 HydrophobicContact CG2-CB 4.42Å; V241-V290 HydrophobicContact CG2-CG1 4.17Å; V241-V290 HydrophobicContact CG2-CG2 3.38Å; I242-V290 PolarHBondContact O-N 2.99Å; P288-V290 PolarHBondContact O-N 3.18Å; V290-I313 WeakPolarHBondContact O-CB 3.32Å; V290-Q314 WeakPolarHBondContact O-CB 3.37Å; V290-Q314 PolarHBondContact O-N 3.43Å; V290-F428 HydrophobicContact CG2-CE1 4.49Å; V290-F428 HydrophobicContact CG2-CZ 4.08Å
291S98.9Very high98.5Very high2 Ų232 Ų321%0.01416%0.163CC..EExtended strand (participates in β ladder)trans-146.6128.9179.2-169.50000110.4G243 M244 Q314 V316G243-S291 CarbonylContact C-O 3.53Å; G243-S291 VanDerWaalsContact CA-O 3.28Å; G243-S291 WeakPolarHBondContact CA-O 3.42Å; M244-S291 PolarHBondContact N-O 3.3Å; S291-Q314 CarbonylContact C-O 3.57Å; S291-Q314 VanDerWaalsContact CA-O 3.3Å; S291-Q314 WeakPolarHBondContact CA-O 3.39Å; S291-Q314 PolarHBondContact OG-NE2 2.94Å; S291-V316 WeakPolarHBondContact OG-CG2 3.39Å
292I98.9Very high98.5Very high0 Ų029.7 Ų29.70%016%0.164CC..EExtended strand (participates in β ladder)trans-127.4123.2171-63.3178.2000108.4M244 V246 Y280 I284 V289 P295 F307 I313 Q314 V315 V316M244-I292 HydrophobicContact CB-CG1 4.46Å; M244-I292 CarbonylContact O-C 3.48Å; M244-I292 WeakPolarHBondContact O-CA 3.47Å; V246-I292 HydrophobicContact CG2-CG2 3.77Å; Y280-I292 HydrophobicContact CD1-CD1 4.39Å; Y280-I292 HydrophobicContact CG-CD1 4.29Å; I284-I292 HydrophobicContact CD1-CD1 4.18Å; I284-I292 HydrophobicContact CG1-CD1 4.22Å; V289-I292 HydrophobicContact CG1-CD1 3.99Å; V289-I292 HydrophobicContact CG1-CG1 3.71Å; I292-P295 HydrophobicContact CG2-CB 3.91Å; I292-P295 HydrophobicContact CG2-CG 4.43Å; I292-F307 HydrophobicContact CD1-CZ 4.15Å; I292-I313 HydrophobicContact CB-CD1 4.27Å; I292-I313 HydrophobicContact CD1-CD1 3.93Å; I292-I313 HydrophobicContact CG1-CD1 3.74Å; I292-Q314 PolarHBondContact N-O 3.11Å; I292-V315 CarbonylContact O-C 3.6Å; I292-V315 VanDerWaalsContact O-CA 3.3Å; I292-V315 WeakPolarHBondContact O-CA 3.21Å; I292-V316 PolarHBondContact O-N 2.81Å
293E98.9Very high98.5Very high1 Ų128.2 Ų28.21%0.00515%0.154CC..EExtended strand (participates in β ladder)trans-101.2142.4176-179.6-175.7141.100110.6M244 D245 V246 P295 V316 D318 L341 K394M244-E293 PolarHBondContact O-N 3.45Å; D245-E293 HydrophobicContact CB-CB 3.96Å; D245-E293 HydrophobicContact CB-CG 4.23Å; V246-E293 PolarHBondContact N-O 2.61Å; E293-P295 VanDerWaalsContact C-CD 3.41Å; E293-V316 WeakPolarHBondContact CA-O 3.31Å; E293-V316 HydrophobicContact CB-CB 3.73Å; E293-V316 HydrophobicContact CB-CG1 4.36Å; E293-V316 HydrophobicContact CB-CG2 4.29Å; E293-V316 HydrophobicContact CG-CB 3.9Å; E293-V316 HydrophobicContact CG-CG1 4.05Å; E293-D318 HydrophobicContact CG-CB 3.94Å; E293-D318 WeakPolarHBondContact OE1-CB 3.5Å; E293-L341 WeakPolarHBondContact OE1-CD2 3.45Å; E293-L341 WeakPolarHBondContact OE2-CD1 3.43Å; E293-K394 IonicContact OE1-NZ 2.7Å; E293-K394 PolarHBondContact OE1-NZ 3.36Å; E293-K394 WeakPolarHBondContact OE2-CE 3.46Å; E293-K394 IonicContact OE2-NZ 2.84Å; E293-K394 PolarHBondContact OE2-NZ 2.91Å
294D98.6Very high98.5Very high1 Ų128.1 Ų28.11%0.00515%0.153CC..  trans41.952.8179.9-75.11.8000115A248 F296 W304 V316 D318 D319A248-D294 WeakPolarHBondContact CB-O 3.4Å; A248-D294 PolarHBondContact N-O 2.93Å; A248-D294 VanDerWaalsContact N-O 3.11Å; D294-F296 PolarHBondContact O-N 2.93Å; D294-F296 VanDerWaalsContact O-N 3.13Å; D294-W304 HydrophobicContact CB-CH2 4.42Å; D294-W304 HydrophobicContact CB-CZ2 4.38Å; D294-W304 VanDerWaalsContact OD1-CH2 3.24Å; D294-W304 WeakPolarHBondContact OD1-CH2 3.25Å; D294-V316 PolarHBondContact N-O 2.86Å; D294-V316 VanDerWaalsContact N-O 3.09Å; D294-D318 PolarHBondContact OD1-N 2.67Å; D294-D318 WeakPolarHBondContact OD2-CB 3.37Å; D294-D319 VanDerWaalsContact OD2-CB 3.27Å; D294-D319 WeakPolarHBondContact OD2-CB 3.36Å; D294-D319 PolarHBondContact OD2-N 3.28Å
295P98.8Very high98.5Very high0 Ų029.7 Ų29.70%016%0.16CC..  trans-61.2-21.5179.125.5-35.8000113.8A248 Y280 I292 E293 W304 F307 V315A248-P295 WeakPolarHBondContact CB-O 3.22Å; Y280-P295 HydrophobicContact CD2-CB 3.97Å; Y280-P295 HydrophobicContact CE2-CB 3.4Å; Y280-P295 VanDerWaalsContact CE2-CB 3.4Å; Y280-P295 VanDerWaalsContact CE2-O 3.25Å; Y280-P295 WeakPolarHBondContact CE2-O 3.43Å; Y280-P295 PolarHBondContact OH-O 3.46Å; I292-P295 HydrophobicContact CG2-CB 3.91Å; I292-P295 HydrophobicContact CG2-CG 4.43Å; E293-P295 VanDerWaalsContact C-CD 3.41Å; P295-W304 HydrophobicContact CG-CD2 4.45Å; P295-W304 HydrophobicContact CG-CE3 4.05Å; P295-W304 HydrophobicContact CG-CH2 4.3Å; P295-W304 HydrophobicContact CG-CZ3 4Å; P295-F307 HydrophobicContact CB-CD1 4.16Å; P295-F307 HydrophobicContact CB-CE1 4.11Å; P295-F307 HydrophobicContact CG-CD1 3.98Å; P295-F307 HydrophobicContact CG-CE1 4.15Å; P295-V315 HydrophobicContact CG-CG1 4.04Å
296F98.8Very high98.5Very high2 Ų227.3 Ų27.31%0.00915%0.15CC..SBendtrans-138.4166.1-178.9-55.9-73.1000110.4Y257 P273 L276 A277 Y280 D294 D300 A303 W304 F307Y257-F296 HydrophobicContact CE2-CD1 4.03Å; Y257-F296 AromaticContact CZ-CD1 3.91Å; Y257-F296 WeakPolarHBondContact OH-CA 3.42Å; Y257-F296 VanDerWaalsContact OH-CB 3.31Å; Y257-F296 WeakPolarHBondContact OH-CB 3.42Å; P273-F296 HydrophobicContact CB-CD1 4.38Å; P273-F296 HydrophobicContact CB-CE1 4.35Å; P273-F296 WeakPolarHBondContact O-CE1 3.46Å; L276-F296 HydrophobicContact CB-CE1 4.35Å; L276-F296 HydrophobicContact CD2-CD1 4.27Å; L276-F296 HydrophobicContact CD2-CE1 4.29Å; L276-F296 HydrophobicContact CG-CE1 4.31Å; A277-F296 HydrophobicContact CB-CE1 4.42Å; A277-F296 HydrophobicContact CB-CZ 3.88Å; Y280-F296 HydrophobicContact CD2-CZ 4.28Å; Y280-F296 HydrophobicContact CE2-CE1 4.23Å; Y280-F296 HydrophobicContact CE2-CZ 4.03Å; D294-F296 PolarHBondContact O-N 2.93Å; D294-F296 VanDerWaalsContact O-N 3.13Å; F296-D300 HydrophobicContact CB-CB 4.29Å; F296-A303 HydrophobicContact CB-CB 4.07Å; F296-A303 HydrophobicContact CD1-CB 3.5Å; F296-A303 HydrophobicContact CD2-CB 3.85Å; F296-A303 HydrophobicContact CE1-CB 3.88Å; F296-A303 HydrophobicContact CE2-CB 4.23Å; F296-A303 HydrophobicContact CG-CB 3.49Å; F296-A303 VanDerWaalsContact CG-CB 3.49Å; F296-A303 HydrophobicContact CZ-CB 4.24Å; F296-W304 HydrophobicContact CB-CG 4.34Å; F296-W304 HydrophobicContact CD2-CD2 4.45Å; F296-W304 HydrophobicContact CD2-CG 4.23Å; F296-W304 WeakPolarHBondContact O-CZ2 3.16Å; F296-W304 PolarHBondContact O-NE1 2.94Å; F296-F307 HydrophobicContact CD2-CB 4.46Å; F296-F307 HydrophobicContact CE2-CB 3.35Å; F296-F307 AromaticContact CE2-CD1 3.9Å; F296-F307 HydrophobicContact CE2-CD1 3.9Å; F296-F307 AromaticContact CE2-CG 3.69Å; F296-F307 HydrophobicContact CE2-CG 3.69Å; F296-F307 HydrophobicContact CZ-CB 3.82Å; F296-F307 HydrophobicContact CZ-CG 4.08Å
297D98.6Very high98.5Very high16 Ų1624.2 Ų24.29%0.08613%0.133CC..  trans-55147.6176.6176.178.1000112F252 Y257 D299 D300 W304F252-D297 HydrophobicContact CB-CB 3.82Å; F252-D297 HydrophobicContact CD1-CB 3.76Å; F252-D297 VanDerWaalsContact CD1-CG 3.47Å; F252-D297 HydrophobicContact CD2-CB 3.8Å; F252-D297 HydrophobicContact CE1-CB 4.18Å; F252-D297 HydrophobicContact CE2-CB 4.2Å; F252-D297 HydrophobicContact CG-CB 3.53Å; F252-D297 HydrophobicContact CZ-CB 4.37Å; Y257-D297 HydrophobicContact CE1-CB 4.28Å; Y257-D297 PolarHBondContact OH-N 3.47Å; D297-D299 PolarHBondContact O-N 3.1Å; D297-D299 PolarHBondContact OD2-N 3Å; D297-D300 HydrophobicContact CB-CB 4.07Å; D297-D300 PolarHBondContact O-N 3.01Å; D297-W304 PolarHBondContact O-NE1 3.17Å
298Q97.8Very high98.6Very high17 Ų1724.8 Ų24.88%0.07914%0.137CC..THydrogen-bonded Turntrans-55.8-16.1-179.165.4-163.5-36.800115.3G42 Y44 S249 D319 L320 R327G42-Q298 VanDerWaalsContact CA-OE1 3.3Å; Y44-Q298 HydrophobicContact CE2-CG 4.4Å; S249-Q298 PolarHBondContact OG-N 3.12Å; S249-Q298 VanDerWaalsContact OG-N 3.1Å; Q298-D319 HydrophobicContact CB-CB 3.97Å; Q298-L320 WeakPolarHBondContact O-CD1 3.33Å; Q298-R327 PolarHBondContact O-NH2 3.14Å
299D98.1Very high98.6Very high60 Ų6026.4 Ų26.432%0.32116%0.156SC..THydrogen-bonded Turntrans-1203.4174.1-73.1-43.2000114.7Y44 D297 W301 R327Y44-D299 WeakPolarHBondContact CE2-OD1 3.47Å; Y44-D299 WeakPolarHBondContact CE2-OD2 3.22Å; Y44-D299 VanDerWaalsContact OH-CG 3.26Å; Y44-D299 PolarHBondContact OH-OD1 3.34Å; Y44-D299 PolarHBondContact OH-OD2 3.44Å; D297-D299 PolarHBondContact O-N 3.1Å; D297-D299 PolarHBondContact OD2-N 3Å; D299-W301 PolarHBondContact O-N 3.38Å; D299-R327 IonicContact OD1-CZ 3.41Å; D299-R327 IonicContact OD1-NH1 3.87Å; D299-R327 IonicContact OD1-NH2 3.92Å; D299-R327 PolarHBondContact OD1-NH2 2.77Å
300D98.1Very high98.5Very high32 Ų3229.5 Ų29.517%0.17118%0.177CC..  trans-81.754173.6-168.3-0.1000112.1Y257 P273 F296 D297 G302 A303 W304Y257-D300 WeakPolarHBondContact OH-CB 3.48Å; Y257-D300 PolarHBondContact OH-OD2 2.97Å; P273-D300 WeakPolarHBondContact CG-OD2 3.22Å; F296-D300 HydrophobicContact CB-CB 4.29Å; D297-D300 HydrophobicContact CB-CB 4.07Å; D297-D300 PolarHBondContact O-N 3.01Å; D300-G302 PolarHBondContact O-N 2.99Å; D300-G302 VanDerWaalsContact O-N 3.08Å; D300-A303 HydrophobicContact CB-CB 4.36Å; D300-A303 PolarHBondContact O-N 3Å; D300-A303 WeakPolarHBondContact OD1-CB 3.33Å; D300-A303 PolarHBondContact OD1-N 2.78Å; D300-A303 VanDerWaalsContact OD2-CB 3.29Å; D300-A303 WeakPolarHBondContact OD2-CB 3.46Å; D300-W304 VanDerWaalsContact O-CD1 3.24Å; D300-W304 PolarHBondContact O-N 2.55Å
301W98.5Very high98.4Very high22 Ų2228.1 Ų28.18%0.08317%0.17CC..Hα-helixtrans-50.1-37.9-175.7-69.994.8000113.1D299 W304 Q305 L320 K330 A331 E334 S336D299-W301 PolarHBondContact O-N 3.38Å; W301-W304 PolarHBondContact O-N 3Å; W301-Q305 VanDerWaalsContact O-CG 3.23Å; W301-Q305 WeakPolarHBondContact O-CG 3.4Å; W301-Q305 PolarHBondContact O-N 3.37Å; W301-L320 HydrophobicContact CD2-CD1 4.08Å; W301-L320 HydrophobicContact CE3-CD1 3.92Å; W301-L320 HydrophobicContact CH2-CD1 3.57Å; W301-L320 HydrophobicContact CH2-CG 4.01Å; W301-L320 HydrophobicContact CZ2-CD1 3.75Å; W301-L320 HydrophobicContact CZ3-CD1 3.63Å; W301-L320 HydrophobicContact CZ3-CD2 4.27Å; W301-L320 HydrophobicContact CZ3-CG 4.13Å; W301-K330 HydrophobicContact CD2-CD 4.37Å; W301-K330 VanDerWaalsContact CE2-CE 3.46Å; W301-K330 HydrophobicContact CE3-CG 4.49Å; W301-K330 HydrophobicContact CH2-CB 4.14Å; W301-K330 HydrophobicContact CH2-CD 3.78Å; W301-K330 HydrophobicContact CH2-CG 3.85Å; W301-K330 HydrophobicContact CZ2-CD 3.53Å; W301-K330 HydrophobicContact CZ2-CG 4.15Å; W301-K330 HydrophobicContact CZ3-CD 4.29Å; W301-K330 HydrophobicContact CZ3-CG 4.06Å; W301-A331 HydrophobicContact CH2-CB 3.96Å; W301-A331 HydrophobicContact CZ3-CB 3.63Å; W301-E334 WeakPolarHBondContact CB-OE2 3.42Å; W301-S336 VanDerWaalsContact CE3-OG 3.26Å; W301-S336 WeakPolarHBondContact CZ3-OG 3.29Å
302G98.3Very high98.3Very high38 Ų3831.6 Ų31.639%0.39221%0.206SC..Hα-helixtrans-64-40.6178.900000113.4D300 K306D300-G302 PolarHBondContact O-N 2.99Å; D300-G302 VanDerWaalsContact O-N 3.08Å; G302-K306 WeakPolarHBondContact O-CG 3.5Å; G302-K306 PolarHBondContact O-N 3.13Å
303A98.6Very high98.3Very high6 Ų632.5 Ų32.55%0.0521%0.211CC..Hα-helixtrans-68-43.2176.700000111.8P273 F296 D300 Q305 K306 F307P273-A303 HydrophobicContact CB-CB 3.71Å; F296-A303 HydrophobicContact CB-CB 4.07Å; F296-A303 HydrophobicContact CD1-CB 3.5Å; F296-A303 HydrophobicContact CD2-CB 3.85Å; F296-A303 HydrophobicContact CE1-CB 3.88Å; F296-A303 HydrophobicContact CE2-CB 4.23Å; F296-A303 HydrophobicContact CG-CB 3.49Å; F296-A303 VanDerWaalsContact CG-CB 3.49Å; F296-A303 HydrophobicContact CZ-CB 4.24Å; D300-A303 HydrophobicContact CB-CB 4.36Å; D300-A303 PolarHBondContact O-N 3Å; D300-A303 WeakPolarHBondContact OD1-CB 3.33Å; D300-A303 PolarHBondContact OD1-N 2.78Å; D300-A303 VanDerWaalsContact OD2-CB 3.29Å; D300-A303 WeakPolarHBondContact OD2-CB 3.46Å; A303-Q305 PolarHBondContact O-N 2.89Å; A303-K306 PolarHBondContact O-N 2.65Å; A303-F307 WeakPolarHBondContact O-CB 3.49Å; A303-F307 PolarHBondContact O-N 2.84Å
304W98.8Very high98.3Very high0 Ų032.4 Ų32.40%021%0.211CC..Hα-helixtrans-54.2-51.3174.1-79.295.5000112.3D294 P295 F296 D297 D300 W301 K306 F307 T308 V315 V316 L320 C337D294-W304 HydrophobicContact CB-CH2 4.42Å; D294-W304 HydrophobicContact CB-CZ2 4.38Å; D294-W304 VanDerWaalsContact OD1-CH2 3.24Å; D294-W304 WeakPolarHBondContact OD1-CH2 3.25Å; P295-W304 HydrophobicContact CG-CD2 4.45Å; P295-W304 HydrophobicContact CG-CE3 4.05Å; P295-W304 HydrophobicContact CG-CH2 4.3Å; P295-W304 HydrophobicContact CG-CZ3 4Å; F296-W304 HydrophobicContact CB-CG 4.34Å; F296-W304 HydrophobicContact CD2-CD2 4.45Å; F296-W304 HydrophobicContact CD2-CG 4.23Å; F296-W304 WeakPolarHBondContact O-CZ2 3.16Å; F296-W304 PolarHBondContact O-NE1 2.94Å; D297-W304 PolarHBondContact O-NE1 3.17Å; D300-W304 VanDerWaalsContact O-CD1 3.24Å; D300-W304 PolarHBondContact O-N 2.55Å; W301-W304 PolarHBondContact O-N 3Å; W304-K306 PolarHBondContact O-N 3Å; W304-F307 PolarHBondContact O-N 3.13Å; W304-T308 VanDerWaalsContact O-CB 3.3Å; W304-T308 WeakPolarHBondContact O-CB 3.12Å; W304-T308 PolarHBondContact O-N 2.82Å; W304-T308 PolarHBondContact O-OG1 3.41Å; W304-T308 VanDerWaalsContact O-OG1 3.12Å; W304-V315 HydrophobicContact CE3-CG1 4Å; W304-V315 HydrophobicContact CZ3-CG1 3.8Å; W304-V316 WeakPolarHBondContact CH2-O 3.36Å; W304-L320 HydrophobicContact CD2-CD1 4.43Å; W304-L320 HydrophobicContact CD2-CD2 3.69Å; W304-L320 HydrophobicContact CE3-CD2 3.72Å; W304-L320 HydrophobicContact CG-CD1 4.46Å; W304-L320 HydrophobicContact CG-CD2 4.25Å; W304-L320 HydrophobicContact CH2-CB 3.92Å; W304-L320 HydrophobicContact CH2-CD2 3.91Å; W304-L320 HydrophobicContact CH2-CG 4.49Å; W304-L320 HydrophobicContact CZ2-CB 3.64Å; W304-L320 HydrophobicContact CZ2-CD1 4.48Å; W304-L320 HydrophobicContact CZ2-CD2 3.97Å; W304-L320 HydrophobicContact CZ2-CG 4.23Å; W304-L320 HydrophobicContact CZ3-CD2 3.8Å; W304-C337 HydrophobicContact CE3-CB 4.03Å; W304-C337 HydrophobicContact CZ3-CB 3.8Å
305Q98.5Very high98.3Very high74 Ų7432.4 Ų32.435%0.34621%0.21SC..Hα-helixtrans-59-49.5-179.9-67.8179.230.200112.1W301 A303 F307 A309 E334W301-Q305 VanDerWaalsContact O-CG 3.23Å; W301-Q305 WeakPolarHBondContact O-CG 3.4Å; W301-Q305 PolarHBondContact O-N 3.37Å; A303-Q305 PolarHBondContact O-N 2.89Å; Q305-F307 PolarHBondContact O-N 3.11Å; Q305-A309 WeakPolarHBondContact O-CB 3.47Å; Q305-A309 PolarHBondContact O-N 2.83Å; Q305-A309 VanDerWaalsContact O-N 3.1Å; Q305-E334 HydrophobicContact CG-CB 4.17Å; Q305-E334 VanDerWaalsContact CG-O 3.26Å; Q305-E334 WeakPolarHBondContact CG-O 3.39Å; Q305-E334 PolarHBondContact NE2-OE2 2.9Å
306K98.3Very high98.3Very high125 Ų12532.4 Ų32.454%0.54321%0.21SC..Hα-helixtrans-60.4-45.3-179.8-74.8174.2173.9-1770112D274 G302 A303 W304 S310D274-K306 IonicContact OD1-NZ 2.63Å; D274-K306 PolarHBondContact OD1-NZ 2.85Å; D274-K306 IonicContact OD2-NZ 3.87Å; G302-K306 WeakPolarHBondContact O-CG 3.5Å; G302-K306 PolarHBondContact O-N 3.13Å; A303-K306 PolarHBondContact O-N 2.65Å; W304-K306 PolarHBondContact O-N 3Å; K306-S310 PolarHBondContact O-OG 3.03Å
307F98.8Very high98.3Very high2 Ų232.3 Ų32.31%0.00921%0.21CC..Hα-helixtrans-69.4-49.5-178.6180-113.3000111.4A277 Y280 I284 I292 P295 F296 A303 W304 Q305 A309 S310 A311 V315A277-F307 HydrophobicContact CB-CD2 4.12Å; Y280-F307 HydrophobicContact CD2-CD2 4.45Å; Y280-F307 HydrophobicContact CD2-CE1 4.41Å; Y280-F307 HydrophobicContact CD2-CE2 4.01Å; Y280-F307 AromaticContact CD2-CZ 3.99Å; Y280-F307 HydrophobicContact CD2-CZ 3.99Å; Y280-F307 HydrophobicContact CG-CE2 4.31Å; Y280-F307 HydrophobicContact CG-CZ 4.2Å; I284-F307 HydrophobicContact CD1-CE2 4.47Å; I284-F307 HydrophobicContact CD1-CZ 4.13Å; I292-F307 HydrophobicContact CD1-CZ 4.15Å; P295-F307 HydrophobicContact CB-CD1 4.16Å; P295-F307 HydrophobicContact CB-CE1 4.11Å; P295-F307 HydrophobicContact CG-CD1 3.98Å; P295-F307 HydrophobicContact CG-CE1 4.15Å; F296-F307 HydrophobicContact CD2-CB 4.46Å; F296-F307 HydrophobicContact CE2-CB 3.35Å; F296-F307 AromaticContact CE2-CD1 3.9Å; F296-F307 HydrophobicContact CE2-CD1 3.9Å; F296-F307 AromaticContact CE2-CG 3.69Å; F296-F307 HydrophobicContact CE2-CG 3.69Å; F296-F307 HydrophobicContact CZ-CB 3.82Å; F296-F307 HydrophobicContact CZ-CG 4.08Å; A303-F307 WeakPolarHBondContact O-CB 3.49Å; A303-F307 PolarHBondContact O-N 2.84Å; W304-F307 PolarHBondContact O-N 3.13Å; Q305-F307 PolarHBondContact O-N 3.11Å; F307-A309 PolarHBondContact O-N 2.78Å; F307-S310 CarbonylContact O-C 3.58Å; F307-S310 PolarHBondContact O-N 2.97Å; F307-S310 PolarHBondContact O-OG 3.39Å; F307-A311 HydrophobicContact CD1-CB 4.23Å; F307-A311 HydrophobicContact CD2-CB 4.38Å; F307-A311 HydrophobicContact CE1-CB 3.9Å; F307-A311 HydrophobicContact CE2-CB 4.05Å; F307-A311 HydrophobicContact CG-CB 4.47Å; F307-A311 HydrophobicContact CZ-CB 3.79Å; F307-A311 WeakPolarHBondContact O-CB 3.43Å; F307-A311 PolarHBondContact O-N 3.02Å; F307-V315 HydrophobicContact CD1-CG1 4.49Å; F307-V315 HydrophobicContact CD1-CG2 4.24Å; F307-V315 HydrophobicContact CE1-CG2 4.02Å
308T98.8Very high98.3Very high22 Ų2231.6 Ų31.614%0.13521%0.206CC..Hα-helixtrans-58.5-35.5-179.9-67.50000112.3W304 S310 V315 K335 S336W304-T308 VanDerWaalsContact O-CB 3.3Å; W304-T308 WeakPolarHBondContact O-CB 3.12Å; W304-T308 PolarHBondContact O-N 2.82Å; W304-T308 PolarHBondContact O-OG1 3.41Å; W304-T308 VanDerWaalsContact O-OG1 3.12Å; T308-S310 PolarHBondContact O-N 3.08Å; T308-V315 WeakPolarHBondContact OG1-CG1 3.38Å; T308-K335 WeakPolarHBondContact CG2-O 3.48Å; T308-S336 WeakPolarHBondContact CB-O 3.37Å; T308-S336 PolarHBondContact OG1-O 2.88Å
309A98.3Very high98.3Very high92 Ų9230.9 Ų30.976%0.7620%0.203SC*.Hα-helixtrans-63.8-22.8175.400000114.3Q305 F307Q305-A309 WeakPolarHBondContact O-CB 3.47Å; Q305-A309 PolarHBondContact O-N 2.83Å; Q305-A309 VanDerWaalsContact O-N 3.1Å; F307-A309 PolarHBondContact O-N 2.78Å
310S97.1Very high98.3Very high69 Ų6928 Ų2848%0.48319%0.188SC..Hα-helixtrans-120-11.6-175.161.20000115K306 F307 T308 G312K306-S310 PolarHBondContact O-OG 3.03Å; F307-S310 CarbonylContact O-C 3.58Å; F307-S310 PolarHBondContact O-N 2.97Å; F307-S310 PolarHBondContact O-OG 3.39Å; T308-S310 PolarHBondContact O-N 3.08Å; S310-G312 PolarHBondContact O-N 3.35Å
311A97.1Very high98.3Very high9 Ų926.5 Ų26.57%0.07418%0.18CC..Hα-helixtrans-68.8-33.7-172.400000113.9I284 F307 I313 V315I284-A311 HydrophobicContact CD1-CB 4.49Å; F307-A311 HydrophobicContact CD1-CB 4.23Å; F307-A311 HydrophobicContact CD2-CB 4.38Å; F307-A311 HydrophobicContact CE1-CB 3.9Å; F307-A311 HydrophobicContact CE2-CB 4.05Å; F307-A311 HydrophobicContact CG-CB 4.47Å; F307-A311 HydrophobicContact CZ-CB 3.79Å; F307-A311 WeakPolarHBondContact O-CB 3.43Å; F307-A311 PolarHBondContact O-N 3.02Å; A311-I313 HydrophobicContact CB-CG1 4.05Å; A311-I313 PolarHBondContact O-N 3.46Å; A311-V315 HydrophobicContact CB-CG2 4.01Å
312G97.2Very high98.3Very high76 Ų7625.5 Ų25.578%0.78418%0.176SC*.  trans67.81.5179.700000115.7S310S310-G312 PolarHBondContact O-N 3.35Å
313I98.7Very high98.3Very high18 Ų1823.7 Ų23.79%0.09216%0.157CC..SBendtrans-118.1-173.2-177.662.1156.1000111.5I284 V289 V290 I292 A311 N338 R429I284-I313 HydrophobicContact CD1-CD1 3.66Å; I284-I313 HydrophobicContact CD1-CG1 3.93Å; I284-I313 HydrophobicContact CG1-CD1 3.88Å; I284-I313 HydrophobicContact CG1-CG1 4.49Å; I284-I313 HydrophobicContact CG2-CG2 3.96Å; V289-I313 HydrophobicContact CG1-CD1 4.28Å; V290-I313 WeakPolarHBondContact O-CB 3.32Å; I292-I313 HydrophobicContact CB-CD1 4.27Å; I292-I313 HydrophobicContact CD1-CD1 3.93Å; I292-I313 HydrophobicContact CG1-CD1 3.74Å; A311-I313 HydrophobicContact CB-CG1 4.05Å; A311-I313 PolarHBondContact O-N 3.46Å; I313-N338 PolarHBondContact O-ND2 3.28Å; I313-R429 PolarHBondContact O-NH2 3.39Å
314Q98.9Very high98.2Very high0 Ų025 Ų250%016%0.163CC..EExtended strand (participates in β ladder)trans-73129.2167.5-174.7170-9100109.9V290 S291 I292 V316 N338 C339V290-Q314 WeakPolarHBondContact O-CB 3.37Å; V290-Q314 PolarHBondContact O-N 3.43Å; S291-Q314 CarbonylContact C-O 3.57Å; S291-Q314 VanDerWaalsContact CA-O 3.3Å; S291-Q314 WeakPolarHBondContact CA-O 3.39Å; S291-Q314 PolarHBondContact OG-NE2 2.94Å; I292-Q314 PolarHBondContact N-O 3.11Å; Q314-V316 HydrophobicContact CG-CG2 3.9Å; Q314-N338 WeakPolarHBondContact CA-OD1 3.45Å; Q314-C339 VanDerWaalsContact CD-SG 3.6Å; Q314-C339 HydrophobicContact CG-CB 3.49Å; Q314-C339 VanDerWaalsContact CG-CB 3.49Å
315V98.9Very high98Very high0 Ų027 Ų270%018%0.176CC..EExtended strand (participates in β ladder)trans-118117171.6-177.10000107I292 P295 W304 F307 T308 A311 C337 N338 C339I292-V315 CarbonylContact O-C 3.6Å; I292-V315 VanDerWaalsContact O-CA 3.3Å; I292-V315 WeakPolarHBondContact O-CA 3.21Å; P295-V315 HydrophobicContact CG-CG1 4.04Å; W304-V315 HydrophobicContact CE3-CG1 4Å; W304-V315 HydrophobicContact CZ3-CG1 3.8Å; F307-V315 HydrophobicContact CD1-CG1 4.49Å; F307-V315 HydrophobicContact CD1-CG2 4.24Å; F307-V315 HydrophobicContact CE1-CG2 4.02Å; T308-V315 WeakPolarHBondContact OG1-CG1 3.38Å; A311-V315 HydrophobicContact CB-CG2 4.01Å; V315-C337 HydrophobicContact CB-CB 4.36Å; V315-C337 HydrophobicContact CG1-CB 4.01Å; V315-C337 WeakPolarHBondContact O-CB 3.25Å; V315-N338 PolarHBondContact N-OD1 3.21Å; V315-N338 PolarHBondContact O-N 2.67Å; V315-N338 PolarHBondContact O-OD1 2.51Å; V315-C339 PolarHBondContact O-N 3.29Å
316V98.9Very high97.9Very high0 Ų030 Ų300%019%0.188CC..EExtended strand (participates in β ladder)trans-102.9128.3-171.4-169.40000109.3S291 I292 E293 D294 W304 Q314 C339 L341S291-V316 WeakPolarHBondContact OG-CG2 3.39Å; I292-V316 PolarHBondContact O-N 2.81Å; E293-V316 WeakPolarHBondContact CA-O 3.31Å; E293-V316 HydrophobicContact CB-CB 3.73Å; E293-V316 HydrophobicContact CB-CG1 4.36Å; E293-V316 HydrophobicContact CB-CG2 4.29Å; E293-V316 HydrophobicContact CG-CB 3.9Å; E293-V316 HydrophobicContact CG-CG1 4.05Å; D294-V316 PolarHBondContact N-O 2.86Å; D294-V316 VanDerWaalsContact N-O 3.09Å; W304-V316 WeakPolarHBondContact CH2-O 3.36Å; Q314-V316 HydrophobicContact CG-CG2 3.9Å; V316-C339 CarbonylContact C-O 3.59Å; V316-C339 WeakPolarHBondContact CA-O 3.27Å; V316-C339 HydrophobicContact CB-CB 4.29Å; V316-C339 HydrophobicContact CG1-CB 4.33Å; V316-C339 HydrophobicContact CG2-CB 3.93Å; V316-L341 HydrophobicContact CG1-CB 3.76Å; V316-L341 HydrophobicContact CG1-CD1 4.18Å
317G98.8Very high97.9Very high0 Ų025.5 Ų25.50%017%0.168CC..EExtended strand (participates in β ladder)trans-94.2116.4169.200000111.2T321 C339 L341G317-T321 PolarHBondContact O-OG1 3.06Å; G317-C339 PolarHBondContact N-O 2.96Å; G317-L341 PolarHBondContact O-N 3.42Å
318D98.3Very high97.9Very high2 Ų225.4 Ų25.41%0.01117%0.167CC..SBendtrans-104.5-85.9170.5175.926.6000109.9E293 D294 L320 T321 V322 L341 K343 Q346E293-D318 HydrophobicContact CG-CB 3.94Å; E293-D318 WeakPolarHBondContact OE1-CB 3.5Å; D294-D318 PolarHBondContact OD1-N 2.67Å; D294-D318 WeakPolarHBondContact OD2-CB 3.37Å; D318-L320 PolarHBondContact O-N 3.36Å; D318-T321 PolarHBondContact O-N 3.44Å; D318-V322 WeakPolarHBondContact O-CA 3.44Å; D318-V322 PolarHBondContact O-N 3.24Å; D318-L341 HydrophobicContact CB-CB 3.83Å; D318-L341 HydrophobicContact CB-CD2 3.65Å; D318-L341 HydrophobicContact CB-CG 4.38Å; D318-L341 WeakPolarHBondContact OD1-CD2 3.47Å; D318-K343 WeakPolarHBondContact OD1-CD 3.33Å; D318-K343 IonicContact OD1-NZ 3.48Å; D318-K343 PolarHBondContact OD1-NZ 2.84Å; D318-K343 IonicContact OD2-NZ 3.69Å; D318-K343 PolarHBondContact OD2-NZ 2.91Å; D318-Q346 PolarHBondContact OD1-NE2 3.42Å
319D96.6Very high97.9Very high2 Ų226.2 Ų26.21%0.01118%0.176CC..THydrogen-bonded Turntrans-62.6-27.2178.3-70.9-24.7000112G42 D294 Q298 T321 V322G42-D319 VanDerWaalsContact CA-OD1 3.29Å; G42-D319 WeakPolarHBondContact CA-OD1 3.49Å; G42-D319 PolarHBondContact N-OD1 3.1Å; D294-D319 VanDerWaalsContact OD2-CB 3.27Å; D294-D319 WeakPolarHBondContact OD2-CB 3.36Å; D294-D319 PolarHBondContact OD2-N 3.28Å; Q298-D319 HydrophobicContact CB-CB 3.97Å; D319-T321 PolarHBondContact O-N 3Å; D319-V322 WeakPolarHBondContact O-CG1 3.47Å
320L98.4Very high97.9Very high0 Ų025.6 Ų25.60%016%0.156CC..THydrogen-bonded Turntrans-57.3-39.1172.1-179.669.6000112Q298 W301 W304 D318 R327 A331 C337Q298-L320 WeakPolarHBondContact O-CD1 3.33Å; W301-L320 HydrophobicContact CD2-CD1 4.08Å; W301-L320 HydrophobicContact CE3-CD1 3.92Å; W301-L320 HydrophobicContact CH2-CD1 3.57Å; W301-L320 HydrophobicContact CH2-CG 4.01Å; W301-L320 HydrophobicContact CZ2-CD1 3.75Å; W301-L320 HydrophobicContact CZ3-CD1 3.63Å; W301-L320 HydrophobicContact CZ3-CD2 4.27Å; W301-L320 HydrophobicContact CZ3-CG 4.13Å; W304-L320 HydrophobicContact CD2-CD1 4.43Å; W304-L320 HydrophobicContact CD2-CD2 3.69Å; W304-L320 HydrophobicContact CE3-CD2 3.72Å; W304-L320 HydrophobicContact CG-CD1 4.46Å; W304-L320 HydrophobicContact CG-CD2 4.25Å; W304-L320 HydrophobicContact CH2-CB 3.92Å; W304-L320 HydrophobicContact CH2-CD2 3.91Å; W304-L320 HydrophobicContact CH2-CG 4.49Å; W304-L320 HydrophobicContact CZ2-CB 3.64Å; W304-L320 HydrophobicContact CZ2-CD1 4.48Å; W304-L320 HydrophobicContact CZ2-CD2 3.97Å; W304-L320 HydrophobicContact CZ2-CG 4.23Å; W304-L320 HydrophobicContact CZ3-CD2 3.8Å; D318-L320 PolarHBondContact O-N 3.36Å; L320-R327 WeakPolarHBondContact O-CD 3.42Å; L320-R327 PolarHBondContact O-NE 3Å; L320-A331 HydrophobicContact CD2-CB 4.21Å; L320-C337 HydrophobicContact CD2-CB 4.45Å
321T98.6Very high98Very high0 Ų022.3 Ų22.30%013%0.133CC..THydrogen-bonded Turntrans-114.5-24.7-169.169.80000114.1G317 D318 D319 T323 N324 I328 A331 L340G317-T321 PolarHBondContact O-OG1 3.06Å; D318-T321 PolarHBondContact O-N 3.44Å; D319-T321 PolarHBondContact O-N 3Å; T321-T323 PolarHBondContact O-N 3.19Å; T321-N324 WeakPolarHBondContact O-CB 3.28Å; T321-N324 PolarHBondContact O-N 3.3Å; T321-I328 HydrophobicContact CG2-CG1 4.34Å; T321-A331 HydrophobicContact CG2-CB 4.16Å; T321-L340 WeakPolarHBondContact OG1-CD1 3.29Å
322V97.6Very high98Very high0 Ų023 Ų230%014%0.136CC..THydrogen-bonded Turntrans42.836.7179.3-66.90000113.8E45 D318 D319 N324 Q346E45-V322 HydrophobicContact CG-CB 4.07Å; E45-V322 HydrophobicContact CG-CG1 3.68Å; D318-V322 WeakPolarHBondContact O-CA 3.44Å; D318-V322 PolarHBondContact O-N 3.24Å; D319-V322 WeakPolarHBondContact O-CG1 3.47Å; V322-N324 HydrophobicContact CG2-CB 3.78Å; V322-N324 PolarHBondContact O-N 3.36Å; V322-Q346 VanDerWaalsContact C-OE1 3.25Å; V322-Q346 HydrophobicContact CB-CB 4.44Å; V322-Q346 VanDerWaalsContact O-CB 3.31Å; V322-Q346 WeakPolarHBondContact O-CB 3.29Å
323T98.4Very high98.1Very high0 Ų025.8 Ų25.80%013%0.133CC..THydrogen-bonded Turntrans52.522.3-174.1-47.20000113.4T321 L341 L342 K343 Q346 I347 A356T321-T323 PolarHBondContact O-N 3.19Å; T323-L341 PolarHBondContact OG1-O 3.2Å; T323-L342 HydrophobicContact CG2-CG 4Å; T323-K343 PolarHBondContact OG1-N 3.31Å; T323-K343 PolarHBondContact OG1-O 3.24Å; T323-Q346 PolarHBondContact OG1-OE1 3.34Å; T323-I347 HydrophobicContact CG2-CB 4.21Å; T323-I347 HydrophobicContact CG2-CG2 3.91Å; T323-A356 HydrophobicContact CG2-CB 3.93Å
324N96.9Very high98.1Very high34 Ų3427.6 Ų27.618%0.18214%0.142CC..  trans-99.7119.6-174.4-176.4-45.9000111T321 V322 K326 R327 I328 I347T321-N324 WeakPolarHBondContact O-CB 3.28Å; T321-N324 PolarHBondContact O-N 3.3Å; V322-N324 HydrophobicContact CG2-CB 3.78Å; V322-N324 PolarHBondContact O-N 3.36Å; N324-K326 PolarHBondContact O-N 3Å; N324-K326 VanDerWaalsContact O-N 3.07Å; N324-K326 WeakPolarHBondContact OD1-CB 3.47Å; N324-K326 PolarHBondContact OD1-N 2.89Å; N324-R327 PolarHBondContact O-N 3.08Å; N324-I328 VanDerWaalsContact O-CG1 3.32Å; N324-I328 WeakPolarHBondContact O-CG1 3.37Å; N324-I328 PolarHBondContact O-N 3.45Å; N324-I347 HydrophobicContact CB-CD1 4.27Å
325P95.4Very high98Very high41 Ų4135.1 Ų35.127%0.26617%0.174SC..Hα-helixtrans-53-33-178.6-29.936.4000115.3A329 L359P325-A329 VanDerWaalsContact O-CB 3.28Å; P325-A329 WeakPolarHBondContact O-CB 3.45Å; P325-A329 PolarHBondContact O-N 2.93Å; P325-L359 HydrophobicContact CB-CD2 4.11Å; P325-L359 WeakPolarHBondContact O-CD2 3.34Å
326K96.5Very high98Very high138 Ų13835.1 Ų35.160%0.617%0.174SC*.Hα-helixtrans-67.9-44.7178.4-63.7-178-178177.90111.6E101 N324 A329 K330E101-K326 IonicContact OE1-NZ 2.71Å; E101-K326 PolarHBondContact OE1-NZ 2.62Å; N324-K326 PolarHBondContact O-N 3Å; N324-K326 VanDerWaalsContact O-N 3.07Å; N324-K326 WeakPolarHBondContact OD1-CB 3.47Å; N324-K326 PolarHBondContact OD1-N 2.89Å; K326-A329 PolarHBondContact O-N 2.92Å; K326-K330 PolarHBondContact O-N 3.37Å; K326-K330 VanDerWaalsContact O-N 3.1Å
327R98.1Very high98Very high31 Ų3135.2 Ų35.212%0.11718%0.175CC..Hα-helixtrans-73.3-37178.4-65.7-159.674.6100.7-11.5111.7Y44 Q298 D299 L320 N324 A329 K330 A331Y44-R327 VanDerWaalsContact CD2-CZ 3.46Å; Y44-R327 VanDerWaalsContact CD2-NH1 3.32Å; Y44-R327 VanDerWaalsContact CE2-CZ 3.41Å; Q298-R327 PolarHBondContact O-NH2 3.14Å; D299-R327 IonicContact OD1-CZ 3.41Å; D299-R327 IonicContact OD1-NH1 3.87Å; D299-R327 IonicContact OD1-NH2 3.92Å; D299-R327 PolarHBondContact OD1-NH2 2.77Å; L320-R327 WeakPolarHBondContact O-CD 3.42Å; L320-R327 PolarHBondContact O-NE 3Å; N324-R327 PolarHBondContact O-N 3.08Å; R327-A329 VanDerWaalsContact C-N 3.35Å; R327-A329 PolarHBondContact O-N 3.08Å; R327-K330 PolarHBondContact O-N 2.98Å; R327-A331 WeakPolarHBondContact O-CB 3.4Å; R327-A331 PolarHBondContact O-N 3.27Å
328I98.8Very high98Very high0 Ų037 Ų370%019%0.185CC..Hα-helixtrans-57.9-49171.3-64.6165.1000110.1T321 N324 K330 A331 V332 L340 A356 L359 W365T321-I328 HydrophobicContact CG2-CG1 4.34Å; N324-I328 VanDerWaalsContact O-CG1 3.32Å; N324-I328 WeakPolarHBondContact O-CG1 3.37Å; N324-I328 PolarHBondContact O-N 3.45Å; I328-K330 VanDerWaalsContact C-N 3.32Å; I328-K330 PolarHBondContact O-N 3.15Å; I328-A331 PolarHBondContact O-N 2.92Å; I328-V332 HydrophobicContact CG2-CG2 4.31Å; I328-V332 WeakPolarHBondContact O-CB 3.34Å; I328-V332 VanDerWaalsContact O-CG2 3.32Å; I328-V332 WeakPolarHBondContact O-CG2 3.42Å; I328-V332 PolarHBondContact O-N 3.33Å; I328-L340 HydrophobicContact CD1-CD1 3.87Å; I328-L340 HydrophobicContact CD1-CD2 3.86Å; I328-L340 HydrophobicContact CD1-CG 4.49Å; I328-L340 HydrophobicContact CG1-CD1 4.07Å; I328-A356 HydrophobicContact CD1-CB 3.65Å; I328-L359 HydrophobicContact CB-CD2 3.91Å; I328-L359 HydrophobicContact CG2-CD2 3.63Å; I328-L359 HydrophobicContact CG2-CG 3.83Å; I328-W365 HydrophobicContact CG2-CZ3 4.42Å
329A98.4Very high98.1Very high38 Ų3837 Ų3731%0.31418%0.184SC..Hα-helixtrans-59.9-41.2178.200000112.4P325 K326 R327 N333P325-A329 VanDerWaalsContact O-CB 3.28Å; P325-A329 WeakPolarHBondContact O-CB 3.45Å; P325-A329 PolarHBondContact O-N 2.93Å; K326-A329 PolarHBondContact O-N 2.92Å; R327-A329 VanDerWaalsContact C-N 3.35Å; R327-A329 PolarHBondContact O-N 3.08Å; A329-N333 WeakPolarHBondContact O-CB 3.49Å; A329-N333 PolarHBondContact O-N 2.89Å; A329-N333 PolarHBondContact O-ND2 3.41Å
330K98.5Very high98.2Very high79 Ų7936.9 Ų36.934%0.34318%0.184SC..Hα-helixtrans-60.6-50173.2-177.3178.2173.9-169.50111.5W301 K326 R327 I328 V332 N333 E334W301-K330 HydrophobicContact CD2-CD 4.37Å; W301-K330 VanDerWaalsContact CE2-CE 3.46Å; W301-K330 HydrophobicContact CE3-CG 4.49Å; W301-K330 HydrophobicContact CH2-CB 4.14Å; W301-K330 HydrophobicContact CH2-CD 3.78Å; W301-K330 HydrophobicContact CH2-CG 3.85Å; W301-K330 HydrophobicContact CZ2-CD 3.53Å; W301-K330 HydrophobicContact CZ2-CG 4.15Å; W301-K330 HydrophobicContact CZ3-CD 4.29Å; W301-K330 HydrophobicContact CZ3-CG 4.06Å; K326-K330 PolarHBondContact O-N 3.37Å; K326-K330 VanDerWaalsContact O-N 3.1Å; R327-K330 PolarHBondContact O-N 2.98Å; I328-K330 VanDerWaalsContact C-N 3.32Å; I328-K330 PolarHBondContact O-N 3.15Å; K330-V332 VanDerWaalsContact C-N 3.32Å; K330-V332 PolarHBondContact O-N 2.91Å; K330-N333 PolarHBondContact O-N 2.98Å; K330-N333 VanDerWaalsContact O-N 3.14Å; K330-E334 WeakPolarHBondContact CE-OE1 3.22Å; K330-E334 HydrophobicContact CG-CG 4.48Å; K330-E334 IonicContact NZ-OE1 2.82Å; K330-E334 WeakPolarHBondContact O-CB 3.4Å; K330-E334 PolarHBondContact O-N 3.4Å
331A98.7Very high98.2Very high0 Ų036.9 Ų36.90%018%0.184CC..Hα-helixtrans-65.6-32.6-178.300000113.4W301 L320 T321 R327 I328 K335 S336 W365W301-A331 HydrophobicContact CH2-CB 3.96Å; W301-A331 HydrophobicContact CZ3-CB 3.63Å; L320-A331 HydrophobicContact CD2-CB 4.21Å; T321-A331 HydrophobicContact CG2-CB 4.16Å; R327-A331 WeakPolarHBondContact O-CB 3.4Å; R327-A331 PolarHBondContact O-N 3.27Å; I328-A331 PolarHBondContact O-N 2.92Å; A331-K335 WeakPolarHBondContact O-CA 3.36Å; A331-K335 PolarHBondContact O-N 2.81Å; A331-S336 PolarHBondContact O-N 3.14Å; A331-W365 HydrophobicContact CB-CH2 3.6Å; A331-W365 HydrophobicContact CB-CZ2 4.4Å
332V98.5Very high98.2Very high23 Ų2336.9 Ų36.914%0.13918%0.184CC..Hα-helixtrans-62.2-52.4168.6165.30000110.8I328 K330 E334 K335 N363 W365I328-V332 HydrophobicContact CG2-CG2 4.31Å; I328-V332 WeakPolarHBondContact O-CB 3.34Å; I328-V332 VanDerWaalsContact O-CG2 3.32Å; I328-V332 WeakPolarHBondContact O-CG2 3.42Å; I328-V332 PolarHBondContact O-N 3.33Å; K330-V332 VanDerWaalsContact C-N 3.32Å; K330-V332 PolarHBondContact O-N 2.91Å; V332-E334 VanDerWaalsContact C-N 3.29Å; V332-E334 PolarHBondContact O-N 3.44Å; V332-K335 PolarHBondContact O-N 3.44Å; V332-K335 VanDerWaalsContact O-N 3.1Å; V332-N363 HydrophobicContact CG1-CB 3.88Å; V332-N363 WeakPolarHBondContact CG1-OD1 3.41Å; V332-N363 HydrophobicContact CG2-CB 3.87Å; V332-W365 HydrophobicContact CB-CZ2 4.22Å; V332-W365 HydrophobicContact CG2-CD2 4.23Å; V332-W365 HydrophobicContact CG2-CH2 3.94Å; V332-W365 HydrophobicContact CG2-CZ2 3.57Å; V332-W365 HydrophobicContact CG2-CZ3 4.42Å
333N98.3Very high98.3Very high135 Ų13537.3 Ų37.372%0.72219%0.186SC*.Hα-helixtrans-61.8-39.2-177.6-71.8-23.6000112.2A329 K330 K335A329-N333 WeakPolarHBondContact O-CB 3.49Å; A329-N333 PolarHBondContact O-N 2.89Å; A329-N333 PolarHBondContact O-ND2 3.41Å; K330-N333 PolarHBondContact O-N 2.98Å; K330-N333 VanDerWaalsContact O-N 3.14Å; N333-K335 VanDerWaalsContact C-N 3.33Å
334E98.1Very high98.3Very high57 Ų5737.7 Ų37.727%0.26619%0.188SC..Hα-helixtrans-81.5-12.2178.9-71.6-171.3-160.400113W301 Q305 K330 V332 S336W301-E334 WeakPolarHBondContact CB-OE2 3.42Å; Q305-E334 HydrophobicContact CG-CB 4.17Å; Q305-E334 VanDerWaalsContact CG-O 3.26Å; Q305-E334 WeakPolarHBondContact CG-O 3.39Å; Q305-E334 PolarHBondContact NE2-OE2 2.9Å; K330-E334 WeakPolarHBondContact CE-OE1 3.22Å; K330-E334 HydrophobicContact CG-CG 4.48Å; K330-E334 IonicContact NZ-OE1 2.82Å; K330-E334 WeakPolarHBondContact O-CB 3.4Å; K330-E334 PolarHBondContact O-N 3.4Å; V332-E334 VanDerWaalsContact C-N 3.29Å; V332-E334 PolarHBondContact O-N 3.44Å; E334-S336 VanDerWaalsContact CB-OG 3.25Å; E334-S336 WeakPolarHBondContact CB-OG 3.4Å; E334-S336 PolarHBondContact O-N 3.31Å
335K98.4Very high98.3Very high158 Ų15836.5 Ų36.569%0.68718%0.181SC*.THydrogen-bonded Turntrans57.739-172.8-52.4179180-179.80112.3T308 A331 V332 N333T308-K335 WeakPolarHBondContact CG2-O 3.48Å; A331-K335 WeakPolarHBondContact O-CA 3.36Å; A331-K335 PolarHBondContact O-N 2.81Å; V332-K335 PolarHBondContact O-N 3.44Å; V332-K335 VanDerWaalsContact O-N 3.1Å; N333-K335 VanDerWaalsContact C-N 3.33Å
336S98.6Very high98.4Very high0 Ų034.7 Ų34.70%017%0.169CC..  trans-74-32.2-173.9-55.40000112.8W301 T308 A331 E334W301-S336 VanDerWaalsContact CE3-OG 3.26Å; W301-S336 WeakPolarHBondContact CZ3-OG 3.29Å; T308-S336 WeakPolarHBondContact CB-O 3.37Å; T308-S336 PolarHBondContact OG1-O 2.88Å; A331-S336 PolarHBondContact O-N 3.14Å; E334-S336 VanDerWaalsContact CB-OG 3.25Å; E334-S336 WeakPolarHBondContact CB-OG 3.4Å; E334-S336 PolarHBondContact O-N 3.31Å
337C98.8Very high98.5Very high2 Ų228.6 Ų28.61%0.01414%0.143CC..  trans-147.9-179.4174.265.10000110W304 V315 L320 W365W304-C337 HydrophobicContact CE3-CB 4.03Å; W304-C337 HydrophobicContact CZ3-CB 3.8Å; V315-C337 HydrophobicContact CB-CB 4.36Å; V315-C337 HydrophobicContact CG1-CB 4.01Å; V315-C337 WeakPolarHBondContact O-CB 3.25Å; L320-C337 HydrophobicContact CD2-CB 4.45Å; C337-W365 WeakPolarHBondContact O-CZ2 3.21Å; C337-W365 PolarHBondContact O-NE1 3.22Å; C337-W365 WeakPolarHBondContact SG-CH2 3.47Å; C337-W365 WeakPolarHBondContact SG-CZ3 3.33Å
338N98.8Very high98.5Very high38 Ų3827.1 Ų27.120%0.20314%0.138CC..SBendtrans-137.615.2-179.566.127.2000113.4I313 Q314 V315 W365 G366 R429I313-N338 PolarHBondContact O-ND2 3.28Å; Q314-N338 WeakPolarHBondContact CA-OD1 3.45Å; V315-N338 PolarHBondContact N-OD1 3.21Å; V315-N338 PolarHBondContact O-N 2.67Å; V315-N338 PolarHBondContact O-OD1 2.51Å; N338-W365 VanDerWaalsContact O-CA 3.31Å; N338-W365 WeakPolarHBondContact O-CA 3.13Å; N338-W365 WeakPolarHBondContact O-CB 2.99Å; N338-G366 PolarHBondContact O-N 3.4Å; N338-R429 PolarHBondContact ND2-NH2 2.64Å
339C98.9Very high98.5Very high0 Ų027.1 Ų27.10%014%0.138CC..EExtended strand (participates in β ladder)trans-149.5140172.7-178.30000109.6Q314 V315 V316 G317 G366Q314-C339 VanDerWaalsContact CD-SG 3.6Å; Q314-C339 HydrophobicContact CG-CB 3.49Å; Q314-C339 VanDerWaalsContact CG-CB 3.49Å; V315-C339 PolarHBondContact O-N 3.29Å; V316-C339 CarbonylContact C-O 3.59Å; V316-C339 WeakPolarHBondContact CA-O 3.27Å; V316-C339 HydrophobicContact CB-CB 4.29Å; V316-C339 HydrophobicContact CG1-CB 4.33Å; V316-C339 HydrophobicContact CG2-CB 3.93Å; G317-C339 PolarHBondContact N-O 2.96Å; C339-G366 CarbonylContact C-O 3.19Å; C339-G366 VanDerWaalsContact CA-O 3.24Å; C339-G366 WeakPolarHBondContact CA-O 3.14Å; C339-G366 VanDerWaalsContact SG-C 3.51Å; C339-G366 PolarHBondContact SG-O 3Å
340L98.9Very high98.6Very high0 Ų025.3 Ų25.30%012%0.123CC..EExtended strand (participates in β ladder)trans-91.9133.2170.9168.264.6000109.3T321 I328 L342 A356 A360 W365 G366 V367 M368T321-L340 WeakPolarHBondContact OG1-CD1 3.29Å; I328-L340 HydrophobicContact CD1-CD1 3.87Å; I328-L340 HydrophobicContact CD1-CD2 3.86Å; I328-L340 HydrophobicContact CD1-CG 4.49Å; I328-L340 HydrophobicContact CG1-CD1 4.07Å; L340-L342 HydrophobicContact CD2-CB 4.36Å; L340-L342 HydrophobicContact CD2-CD1 4.46Å; L340-L342 HydrophobicContact CG-CB 4.4Å; L340-A356 HydrophobicContact CD2-CB 4.18Å; L340-A360 HydrophobicContact CB-CB 3.88Å; L340-A360 HydrophobicContact CD2-CB 4.02Å; L340-W365 HydrophobicContact CB-CE3 4.48Å; L340-G366 PolarHBondContact N-O 3.42Å; L340-V367 HydrophobicContact CB-CG1 4.5Å; L340-V367 HydrophobicContact CB-CG2 4.32Å; L340-V367 HydrophobicContact CD2-CG1 4.32Å; L340-V367 HydrophobicContact CG-CG1 4.47Å; L340-V367 CarbonylContact O-C 3.56Å; L340-V367 WeakPolarHBondContact O-CA 3.5Å; L340-M368 PolarHBondContact O-N 2.88Å
341L98.9Very high98.6Very high0 Ų022.3 Ų22.30%011%0.111CC..EExtended strand (participates in β ladder)trans-84.8120.1156.9-161.880.9000109.2E293 V316 G317 D318 T323 K343 M368 K394E293-L341 WeakPolarHBondContact OE1-CD2 3.45Å; E293-L341 WeakPolarHBondContact OE2-CD1 3.43Å; V316-L341 HydrophobicContact CG1-CB 3.76Å; V316-L341 HydrophobicContact CG1-CD1 4.18Å; G317-L341 PolarHBondContact O-N 3.42Å; D318-L341 HydrophobicContact CB-CB 3.83Å; D318-L341 HydrophobicContact CB-CD2 3.65Å; D318-L341 HydrophobicContact CB-CG 4.38Å; D318-L341 WeakPolarHBondContact OD1-CD2 3.47Å; T323-L341 PolarHBondContact OG1-O 3.2Å; L341-K343 HydrophobicContact CD2-CD 3.91Å; L341-K343 VanDerWaalsContact CD2-CE 3.42Å; L341-K343 HydrophobicContact CD2-CG 4.13Å; L341-M368 WeakPolarHBondContact CA-O 3.43Å; L341-M368 HydrophobicContact CD1-CB 3.94Å; L341-M368 HydrophobicContact CD1-CG 3.92Å; L341-M368 HydrophobicContact CD1-SD 3.9Å; L341-K394 HydrophobicContact CD1-CD 3.78Å; L341-K394 HydrophobicContact CD1-CG 4.13Å
342L98.9Very high98.6Very high0 Ų024 Ų240%012%0.119CC..EExtended strand (participates in β ladder)trans-102.4106.5-176.5-171.2157.9000110T323 L340 V344 S353 C357 V367 M368 S370 L384 L388T323-L342 HydrophobicContact CG2-CG 4Å; L340-L342 HydrophobicContact CD2-CB 4.36Å; L340-L342 HydrophobicContact CD2-CD1 4.46Å; L340-L342 HydrophobicContact CG-CB 4.4Å; L342-V344 HydrophobicContact CD2-CG1 3.93Å; L342-S353 WeakPolarHBondContact CD1-O 3.31Å; L342-C357 HydrophobicContact CD1-CB 3.6Å; L342-V367 HydrophobicContact CB-CG1 3.74Å; L342-V367 HydrophobicContact CD1-CG1 3.89Å; L342-V367 HydrophobicContact CG-CG1 4.5Å; L342-M368 PolarHBondContact N-O 3.34Å; L342-S370 PolarHBondContact O-N 3.08Å; L342-L384 HydrophobicContact CD2-CD2 3.9Å; L342-L388 HydrophobicContact CD1-CD1 3.97Å
343K98.8Very high98.6Very high10 Ų1022.9 Ų22.94%0.04311%0.112CC..  trans-115.1108.9173-72167.2167.3164.10108.7D318 T323 L341 N345 Q346D318-K343 WeakPolarHBondContact OD1-CD 3.33Å; D318-K343 IonicContact OD1-NZ 3.48Å; D318-K343 PolarHBondContact OD1-NZ 2.84Å; D318-K343 IonicContact OD2-NZ 3.69Å; D318-K343 PolarHBondContact OD2-NZ 2.91Å; T323-K343 PolarHBondContact OG1-N 3.31Å; T323-K343 PolarHBondContact OG1-O 3.24Å; L341-K343 HydrophobicContact CD2-CD 3.91Å; L341-K343 VanDerWaalsContact CD2-CE 3.42Å; L341-K343 HydrophobicContact CD2-CG 4.13Å; K343-N345 PolarHBondContact O-N 3.1Å; K343-Q346 HydrophobicContact CB-CB 4.27Å; K343-Q346 HydrophobicContact CB-CG 3.59Å; K343-Q346 HydrophobicContact CD-CG 3.99Å; K343-Q346 HydrophobicContact CG-CG 4.45Å; K343-Q346 WeakPolarHBondContact O-CB 3.38Å; K343-Q346 PolarHBondContact O-N 3.43Å
344V98.4Very high98.6Very high7 Ų717 Ų174%0.0428%0.081CC..Hα-helixtrans-57.1-29.5-174-65.60000113.8L112 L342 G348 S353 L384L112-V344 HydrophobicContact CD1-CB 4.07Å; L112-V344 HydrophobicContact CD1-CG2 4.21Å; L112-V344 HydrophobicContact CD2-CG2 4.19Å; L342-V344 HydrophobicContact CD2-CG1 3.93Å; V344-G348 PolarHBondContact O-N 3.05Å; V344-S353 WeakPolarHBondContact CA-OG 3.39Å; V344-L384 HydrophobicContact CG1-CD2 3.46Å; V344-L384 VanDerWaalsContact CG1-CD2 3.46Å
345N98Very high98.6Very high10 Ų1018.6 Ų18.65%0.0539%0.088CC..Hα-helixtrans-80.7-17.1179.778.9-44000114.2V35 P36 L112 K343 I347 R372V35-N345 HydrophobicContact CG1-CB 4.5Å; P36-N345 HydrophobicContact CG-CB 4.35Å; P36-N345 PolarHBondContact O-ND2 3.14Å; P36-N345 VanDerWaalsContact O-ND2 3.17Å; L112-N345 HydrophobicContact CD2-CB 3.43Å; L112-N345 VanDerWaalsContact CD2-CB 3.43Å; K343-N345 PolarHBondContact O-N 3.1Å; N345-I347 VanDerWaalsContact C-N 3.26Å; N345-I347 PolarHBondContact O-N 2.72Å; N345-R372 PolarHBondContact ND2-NH1 2.86Å; N345-R372 VanDerWaalsContact OD1-CD 3.26Å; N345-R372 WeakPolarHBondContact OD1-CD 3.49Å; N345-R372 WeakPolarHBondContact OD1-CG 3.42Å; N345-R372 PolarHBondContact OD1-NH1 2.92Å
346Q97.9Very high98.6Very high2 Ų211.1 Ų11.11%0.0096%0.056CC..Hα-helixtrans-68.8-27.9173.2-67.7-174-41.600112E45 A46 D318 V322 T323 K343E45-Q346 VanDerWaalsContact CD-CG 3.47Å; E45-Q346 HydrophobicContact CG-CB 4.1Å; E45-Q346 HydrophobicContact CG-CG 3.77Å; E45-Q346 PolarHBondContact OE1-NE2 2.76Å; A46-Q346 WeakPolarHBondContact CB-O 3.42Å; A46-Q346 PolarHBondContact N-O 2.82Å; D318-Q346 PolarHBondContact OD1-NE2 3.42Å; V322-Q346 VanDerWaalsContact C-OE1 3.25Å; V322-Q346 HydrophobicContact CB-CB 4.44Å; V322-Q346 VanDerWaalsContact O-CB 3.31Å; V322-Q346 WeakPolarHBondContact O-CB 3.29Å; T323-Q346 PolarHBondContact OG1-OE1 3.34Å; K343-Q346 HydrophobicContact CB-CB 4.27Å; K343-Q346 HydrophobicContact CB-CG 3.59Å; K343-Q346 HydrophobicContact CD-CG 3.99Å; K343-Q346 HydrophobicContact CG-CG 4.45Å; K343-Q346 WeakPolarHBondContact O-CB 3.38Å; K343-Q346 PolarHBondContact O-N 3.43Å
347I98.3Very high98.6Very high10 Ų1011.1 Ų11.15%0.0516%0.056CC..Hα-helixtrans-106.1-29.9176.9-161.156.5000112.9K103 T323 N324 N345 E352 S353K103-I347 WeakPolarHBondContact CD-O 3.31Å; K103-I347 WeakPolarHBondContact CE-O 3.48Å; K103-I347 PolarHBondContact NZ-O 3.23Å; T323-I347 HydrophobicContact CG2-CB 4.21Å; T323-I347 HydrophobicContact CG2-CG2 3.91Å; N324-I347 HydrophobicContact CB-CD1 4.27Å; N345-I347 VanDerWaalsContact C-N 3.26Å; N345-I347 PolarHBondContact O-N 2.72Å; I347-E352 HydrophobicContact CB-CB 4.44Å; I347-E352 HydrophobicContact CG1-CB 3.51Å; I347-E352 HydrophobicContact CG1-CG 4.31Å; I347-E352 HydrophobicContact CG2-CB 4.04Å; I347-S353 VanDerWaalsContact CG2-OG 3.28Å; I347-S353 WeakPolarHBondContact CG2-OG 3.49Å
348G98.1Very high98.6Very high0 Ų015.3 Ų15.30%07%0.074CC..  trans93.45.9166.300000116.6I111 L112 V344I111-G348 WeakPolarHBondContact CG2-O 3.48Å; L112-G348 WeakPolarHBondContact CA-O 3.43Å; L112-G348 PolarHBondContact N-O 3.13Å; V344-G348 PolarHBondContact O-N 3.05Å
349S98.9Very high98.6Very high0 Ų016 Ų160%08%0.077CC..SBendtrans-148.2154.8169.375.50000112.2E352 S353S349-E352 WeakPolarHBondContact CB-OE2 3.36Å; S349-E352 WeakPolarHBondContact OG-CB 3.36Å; S349-E352 WeakPolarHBondContact OG-CG 3.48Å; S349-E352 PolarHBondContact OG-N 3.03Å; S349-E352 VanDerWaalsContact OG-N 3.15Å; S349-E352 PolarHBondContact OG-OE2 3.37Å; S349-S353 WeakPolarHBondContact O-CB 3.42Å; S349-S353 PolarHBondContact O-N 2.88Å; S349-S353 PolarHBondContact O-OG 2.88Å
350V98.9Very high98.6Very high1 Ų116 Ų161%0.0068%0.077CC..Hα-helixtrans-62.3-46.9174.2174.80000109.9Q87 S115 L116 C119 E352 S353 L354 F380Q87-V350 HydrophobicContact CG-CB 4.35Å; Q87-V350 HydrophobicContact CG-CG1 4.26Å; S115-V350 WeakPolarHBondContact OG-CG2 3.14Å; S115-V350 PolarHBondContact OG-N 2.78Å; L116-V350 HydrophobicContact CD2-CG2 3.69Å; L116-V350 HydrophobicContact CG-CG2 4.44Å; C119-V350 HydrophobicContact CB-CG2 4.34Å; V350-E352 PolarHBondContact O-N 3.07Å; V350-S353 WeakPolarHBondContact O-CB 3.45Å; V350-S353 PolarHBondContact O-N 2.9Å; V350-S353 VanDerWaalsContact O-N 3.13Å; V350-L354 HydrophobicContact CG1-CD1 4.24Å; V350-L354 HydrophobicContact CG1-CG 4.22Å; V350-L354 WeakPolarHBondContact O-CG 3.34Å; V350-L354 PolarHBondContact O-N 2.83Å; V350-F380 HydrophobicContact CG1-CZ 4.33Å; V350-F380 HydrophobicContact CG2-CE1 4.28Å; V350-F380 HydrophobicContact CG2-CE2 4.48Å; V350-F380 HydrophobicContact CG2-CZ 3.73Å
351T98.8Very high98.5Very high16 Ų1618.9 Ų18.910%0.0989%0.09CC..Hα-helixtrans-57.2-49.7-178.2-64.50000112.7E88 D91 S353 L354 Q355E88-T351 WeakPolarHBondContact CA-OG1 3.38Å; E88-T351 HydrophobicContact CB-CG2 4.23Å; E88-T351 HydrophobicContact CG-CG2 4.07Å; D91-T351 WeakPolarHBondContact OD2-CB 3.48Å; D91-T351 PolarHBondContact OD2-N 2.82Å; D91-T351 PolarHBondContact OD2-OG1 3.3Å; T351-S353 VanDerWaalsContact C-N 3.27Å; T351-S353 PolarHBondContact O-N 3.43Å; T351-L354 PolarHBondContact O-N 2.8Å; T351-Q355 WeakPolarHBondContact O-CG 3.35Å; T351-Q355 PolarHBondContact O-N 3.16Å
352E98.7Very high98.5Very high34 Ų3423 Ų2316%0.15913%0.125CC..Hα-helixtrans-66.5-32.1179.3-67.7163.2107.800111.6I95 K103 I347 S349 V350 Q355 A356I95-E352 HydrophobicContact CD1-CG 4.19Å; I95-E352 VanDerWaalsContact CD1-OE2 3.28Å; I95-E352 WeakPolarHBondContact CD1-OE2 3.4Å; K103-E352 WeakPolarHBondContact CE-OE2 3.37Å; K103-E352 IonicContact NZ-OE1 3.43Å; K103-E352 PolarHBondContact NZ-OE1 2.89Å; K103-E352 IonicContact NZ-OE2 3.6Å; K103-E352 PolarHBondContact NZ-OE2 2.94Å; I347-E352 HydrophobicContact CB-CB 4.44Å; I347-E352 HydrophobicContact CG1-CB 3.51Å; I347-E352 HydrophobicContact CG1-CG 4.31Å; I347-E352 HydrophobicContact CG2-CB 4.04Å; S349-E352 WeakPolarHBondContact CB-OE2 3.36Å; S349-E352 WeakPolarHBondContact OG-CB 3.36Å; S349-E352 WeakPolarHBondContact OG-CG 3.48Å; S349-E352 PolarHBondContact OG-N 3.03Å; S349-E352 VanDerWaalsContact OG-N 3.15Å; S349-E352 PolarHBondContact OG-OE2 3.37Å; V350-E352 PolarHBondContact O-N 3.07Å; E352-Q355 PolarHBondContact O-N 2.61Å; E352-A356 WeakPolarHBondContact O-CB 3.34Å; E352-A356 PolarHBondContact O-N 3.05Å
353S98.8Very high98.4Very high0 Ų026.7 Ų26.70%014%0.144CC..Hα-helixtrans-64.6-43.7173.7-56.80000112L342 V344 I347 S349 V350 T351 Q355 A356 C357L342-S353 WeakPolarHBondContact CD1-O 3.31Å; V344-S353 WeakPolarHBondContact CA-OG 3.39Å; I347-S353 VanDerWaalsContact CG2-OG 3.28Å; I347-S353 WeakPolarHBondContact CG2-OG 3.49Å; S349-S353 WeakPolarHBondContact O-CB 3.42Å; S349-S353 PolarHBondContact O-N 2.88Å; S349-S353 PolarHBondContact O-OG 2.88Å; V350-S353 WeakPolarHBondContact O-CB 3.45Å; V350-S353 PolarHBondContact O-N 2.9Å; V350-S353 VanDerWaalsContact O-N 3.13Å; T351-S353 VanDerWaalsContact C-N 3.27Å; T351-S353 PolarHBondContact O-N 3.43Å; S353-Q355 VanDerWaalsContact C-N 3.3Å; S353-Q355 PolarHBondContact O-N 2.84Å; S353-A356 PolarHBondContact O-N 3.29Å; S353-C357 PolarHBondContact O-N 3.48Å
354L98.7Very high98.4Very high11 Ų1129.5 Ų29.56%0.05818%0.177CC..Hα-helixtrans-62.6-39.7174.7-60.6-178.2000111I134 L137 V350 T351 C357 K358 L384 L388I134-L354 HydrophobicContact CG2-CD2 4.19Å; L137-L354 HydrophobicContact CB-CD1 3.58Å; L137-L354 HydrophobicContact CD1-CD1 4.35Å; V350-L354 HydrophobicContact CG1-CD1 4.24Å; V350-L354 HydrophobicContact CG1-CG 4.22Å; V350-L354 WeakPolarHBondContact O-CG 3.34Å; V350-L354 PolarHBondContact O-N 2.83Å; T351-L354 PolarHBondContact O-N 2.8Å; L354-C357 PolarHBondContact O-N 2.63Å; L354-K358 WeakPolarHBondContact O-CG 3.26Å; L354-K358 PolarHBondContact O-N 3.03Å; L354-L384 HydrophobicContact CD2-CD1 4.15Å; L354-L388 HydrophobicContact CD2-CD1 4.42Å; L354-L388 HydrophobicContact CD2-CD2 3.4Å; L354-L388 VanDerWaalsContact CD2-CD2 3.4Å; L354-L388 HydrophobicContact CD2-CG 4.09Å
355Q98.6Very high98.4Very high92 Ų9230.3 Ų30.343%0.4318%0.179SC..Hα-helixtrans-65.8-42.8177.1-70.5170.2-600112T351 E352 S353 K358 L359T351-Q355 WeakPolarHBondContact O-CG 3.35Å; T351-Q355 PolarHBondContact O-N 3.16Å; E352-Q355 PolarHBondContact O-N 2.61Å; S353-Q355 VanDerWaalsContact C-N 3.3Å; S353-Q355 PolarHBondContact O-N 2.84Å; Q355-K358 PolarHBondContact O-N 3.39Å; Q355-L359 WeakPolarHBondContact O-CB 3.38Å; Q355-L359 PolarHBondContact O-N 3.04Å
356A98.8Very high98.4Very high0 Ų030.1 Ų30.10%018%0.179CC..Hα-helixtrans-60.3-44.9174.500000111.7T323 I328 L340 E352 S353 L359 A360T323-A356 HydrophobicContact CG2-CB 3.93Å; I328-A356 HydrophobicContact CD1-CB 3.65Å; L340-A356 HydrophobicContact CD2-CB 4.18Å; E352-A356 WeakPolarHBondContact O-CB 3.34Å; E352-A356 PolarHBondContact O-N 3.05Å; S353-A356 PolarHBondContact O-N 3.29Å; A356-L359 PolarHBondContact O-N 2.84Å; A356-A360 PolarHBondContact O-N 2.62Å
357C98.6Very high98.4Very high0 Ų030.1 Ų30.10%018%0.179CC..Hα-helixtrans-58.1-50.2174.2-173.50000111.9L342 S353 L354 L359 A360 Q361 L388L342-C357 HydrophobicContact CD1-CB 3.6Å; S353-C357 PolarHBondContact O-N 3.48Å; L354-C357 PolarHBondContact O-N 2.63Å; C357-L359 VanDerWaalsContact C-N 3.32Å; C357-L359 PolarHBondContact O-N 3.4Å; C357-A360 PolarHBondContact O-N 3.02Å; C357-Q361 WeakPolarHBondContact O-CG 3.3Å; C357-Q361 PolarHBondContact O-N 3.09Å; C357-Q361 VanDerWaalsContact SG-CD 3.59Å; C357-Q361 PolarHBondContact SG-OE1 2.94Å; C357-Q361 VanDerWaalsContact SG-OE1 3.36Å; C357-L388 HydrophobicContact CB-CD1 4.03Å; C357-L388 HydrophobicContact CB-CD2 4.04Å
358K98Very high98.5Very high91 Ų9129.7 Ų29.740%0.39618%0.177SC..Hα-helixtrans-61.1-41.4179.4-73.5-178.5-166.1-1650111.8L137 A138 L354 Q355 Q361 A362L137-K358 PolarHBondContact O-NZ 3.11Å; A138-K358 WeakPolarHBondContact O-CE 3.25Å; A138-K358 PolarHBondContact O-NZ 3.43Å; L354-K358 WeakPolarHBondContact O-CG 3.26Å; L354-K358 PolarHBondContact O-N 3.03Å; Q355-K358 PolarHBondContact O-N 3.39Å; K358-Q361 PolarHBondContact O-N 2.69Å; K358-A362 WeakPolarHBondContact O-CB 3.41Å; K358-A362 PolarHBondContact O-N 3.02Å
359L98.5Very high98.5Very high51 Ų5129.7 Ų29.727%0.26718%0.177SC..Hα-helixtrans-61.3-45.6177.2177.561.9000111.3P325 I328 Q355 A356 C357 N363P325-L359 HydrophobicContact CB-CD2 4.11Å; P325-L359 WeakPolarHBondContact O-CD2 3.34Å; I328-L359 HydrophobicContact CB-CD2 3.91Å; I328-L359 HydrophobicContact CG2-CD2 3.63Å; I328-L359 HydrophobicContact CG2-CG 3.83Å; Q355-L359 WeakPolarHBondContact O-CB 3.38Å; Q355-L359 PolarHBondContact O-N 3.04Å; A356-L359 PolarHBondContact O-N 2.84Å; C357-L359 VanDerWaalsContact C-N 3.32Å; C357-L359 PolarHBondContact O-N 3.4Å; L359-N363 PolarHBondContact O-N 3.01Å; L359-N363 PolarHBondContact O-ND2 3.18Å
360A98.6Very high98.5Very high0 Ų029.9 Ų29.90%018%0.178CC..Hα-helixtrans-62.6-52.7176.700000111.3L340 A356 C357 A362 N363 G364 W365 V367L340-A360 HydrophobicContact CB-CB 3.88Å; L340-A360 HydrophobicContact CD2-CB 4.02Å; A356-A360 PolarHBondContact O-N 2.62Å; C357-A360 PolarHBondContact O-N 3.02Å; A360-A362 VanDerWaalsContact C-N 3.34Å; A360-A362 PolarHBondContact O-N 3.3Å; A360-N363 CarbonylContact O-C 3.59Å; A360-N363 PolarHBondContact O-N 2.73Å; A360-G364 PolarHBondContact O-N 2.87Å; A360-W365 HydrophobicContact CB-CB 4.11Å; A360-W365 HydrophobicContact CB-CE3 4.32Å; A360-W365 WeakPolarHBondContact O-CB 3.16Å; A360-W365 PolarHBondContact O-N 2.84Å; A360-V367 HydrophobicContact CB-CG2 3.72Å
361Q97.9Very high98.5Very high61 Ų6130 Ų3029%0.28518%0.178SC..Hα-helixtrans-61.8-38.8-178.4-72173.8-40.600112.7C357 K358 N363 G364 V367 L388C357-Q361 WeakPolarHBondContact O-CG 3.3Å; C357-Q361 PolarHBondContact O-N 3.09Å; C357-Q361 VanDerWaalsContact SG-CD 3.59Å; C357-Q361 PolarHBondContact SG-OE1 2.94Å; C357-Q361 VanDerWaalsContact SG-OE1 3.36Å; K358-Q361 PolarHBondContact O-N 2.69Å; Q361-N363 PolarHBondContact O-N 2.68Å; Q361-G364 PolarHBondContact O-N 3.28Å; Q361-V367 HydrophobicContact CG-CG2 3.91Å; Q361-L388 PolarHBondContact NE2-O 2.68Å
362A97.4Very high98.4Very high87 Ų8729.4 Ų29.472%0.71918%0.175SC*.Hα-helixtrans-63.7-23.3176.300000113.1K358 A360K358-A362 WeakPolarHBondContact O-CB 3.41Å; K358-A362 PolarHBondContact O-N 3.02Å; A360-A362 VanDerWaalsContact C-N 3.34Å; A360-A362 PolarHBondContact O-N 3.3Å
363N98.1Very high98.1Very high77 Ų7728 Ų2841%0.41217%0.168SC..THydrogen-bonded Turntrans-9716.7174.8-72-77000112.9V332 L359 A360 Q361 W365V332-N363 HydrophobicContact CG1-CB 3.88Å; V332-N363 WeakPolarHBondContact CG1-OD1 3.41Å; V332-N363 HydrophobicContact CG2-CB 3.87Å; L359-N363 PolarHBondContact O-N 3.01Å; L359-N363 PolarHBondContact O-ND2 3.18Å; A360-N363 CarbonylContact O-C 3.59Å; A360-N363 PolarHBondContact O-N 2.73Å; Q361-N363 PolarHBondContact O-N 2.68Å; N363-W365 VanDerWaalsContact C-N 3.26Å; N363-W365 PolarHBondContact O-N 3.05Å
364G97.4Very high98Very high70 Ų7028 Ų2872%0.72217%0.168SC*.THydrogen-bonded Turntrans73.514.3176.700000114.3A360 Q361A360-G364 PolarHBondContact O-N 2.87Å; Q361-G364 PolarHBondContact O-N 3.28Å
365W98.6Very high98Very high24 Ų2427.7 Ų27.79%0.09117%0.167CC..  trans-83.3150.7177-69.613.8000111.9I328 A331 V332 C337 N338 L340 A360 N363I328-W365 HydrophobicContact CG2-CZ3 4.42Å; A331-W365 HydrophobicContact CB-CH2 3.6Å; A331-W365 HydrophobicContact CB-CZ2 4.4Å; V332-W365 HydrophobicContact CB-CZ2 4.22Å; V332-W365 HydrophobicContact CG2-CD2 4.23Å; V332-W365 HydrophobicContact CG2-CH2 3.94Å; V332-W365 HydrophobicContact CG2-CZ2 3.57Å; V332-W365 HydrophobicContact CG2-CZ3 4.42Å; C337-W365 WeakPolarHBondContact O-CZ2 3.21Å; C337-W365 PolarHBondContact O-NE1 3.22Å; C337-W365 WeakPolarHBondContact SG-CH2 3.47Å; C337-W365 WeakPolarHBondContact SG-CZ3 3.33Å; N338-W365 VanDerWaalsContact O-CA 3.31Å; N338-W365 WeakPolarHBondContact O-CA 3.13Å; N338-W365 WeakPolarHBondContact O-CB 2.99Å; L340-W365 HydrophobicContact CB-CE3 4.48Å; A360-W365 HydrophobicContact CB-CB 4.11Å; A360-W365 HydrophobicContact CB-CE3 4.32Å; A360-W365 WeakPolarHBondContact O-CB 3.16Å; A360-W365 PolarHBondContact O-N 2.84Å; N363-W365 VanDerWaalsContact C-N 3.26Å; N363-W365 PolarHBondContact O-N 3.05Å
366G98.8Very high98Very high6 Ų623.5 Ų23.56%0.06215%0.147CC..EExtended strand (participates in β ladder)trans-68.8163.2160.700000111.3N338 C339 L340 R429N338-G366 PolarHBondContact O-N 3.4Å; C339-G366 CarbonylContact C-O 3.19Å; C339-G366 VanDerWaalsContact CA-O 3.24Å; C339-G366 WeakPolarHBondContact CA-O 3.14Å; C339-G366 VanDerWaalsContact SG-C 3.51Å; C339-G366 PolarHBondContact SG-O 3Å; L340-G366 PolarHBondContact N-O 3.42Å; G366-R429 WeakPolarHBondContact CA-O 3.33Å
367V98.9Very high98Very high1 Ų129.5 Ų29.51%0.00618%0.175CC..EExtended strand (participates in β ladder)trans-134.5124.8169.7-178.30000108.2L340 L342 A360 Q361 T390 Q392L340-V367 HydrophobicContact CB-CG1 4.5Å; L340-V367 HydrophobicContact CB-CG2 4.32Å; L340-V367 HydrophobicContact CD2-CG1 4.32Å; L340-V367 HydrophobicContact CG-CG1 4.47Å; L340-V367 CarbonylContact O-C 3.56Å; L340-V367 WeakPolarHBondContact O-CA 3.5Å; L342-V367 HydrophobicContact CB-CG1 3.74Å; L342-V367 HydrophobicContact CD1-CG1 3.89Å; L342-V367 HydrophobicContact CG-CG1 4.5Å; A360-V367 HydrophobicContact CB-CG2 3.72Å; Q361-V367 HydrophobicContact CG-CG2 3.91Å; V367-T390 HydrophobicContact CB-CG2 3.92Å; V367-T390 HydrophobicContact CG1-CG2 3.99Å; V367-T390 WeakPolarHBondContact O-CB 3.36Å; V367-T390 PolarHBondContact O-OG1 3.34Å; V367-Q392 WeakPolarHBondContact O-CG 3.39Å
368M98.9Very high98Very high2 Ų230.4 Ų30.41%0.0118%0.18CC..EExtended strand (participates in β ladder)trans-106.5109172.9-176.9-176.9-61.600108.7A149 L340 L341 L342 Q392 K394A149-M368 HydrophobicContact CB-CE 4.49Å; A149-M368 HydrophobicContact CB-SD 4.48Å; L340-M368 PolarHBondContact O-N 2.88Å; L341-M368 WeakPolarHBondContact CA-O 3.43Å; L341-M368 HydrophobicContact CD1-CB 3.94Å; L341-M368 HydrophobicContact CD1-CG 3.92Å; L341-M368 HydrophobicContact CD1-SD 3.9Å; L342-M368 PolarHBondContact N-O 3.34Å; M368-Q392 HydrophobicContact CB-CG 4.01Å; M368-Q392 HydrophobicContact CG-CG 4.35Å; M368-K394 HydrophobicContact CG-CB 4.39Å; M368-K394 HydrophobicContact CG-CG 4.41Å; M368-K394 HydrophobicContact SD-CB 3.75Å; M368-K394 HydrophobicContact SD-CD 3.91Å; M368-K394 HydrophobicContact SD-CG 3.91Å
369V98.9Very high98.1Very high0 Ų027.8 Ų27.80%017%0.172CC..EExtended strand (participates in β ladder)trans-66.7137.1172.4174.30000108.2I381 L384 V385 L388 T390 Q392 I393 K394V369-I381 HydrophobicContact CG1-CB 3.85Å; V369-I381 HydrophobicContact CG1-CG2 4.31Å; V369-L384 HydrophobicContact CG1-CD2 4.08Å; V369-V385 HydrophobicContact CB-CB 3.83Å; V369-V385 HydrophobicContact CB-CG2 4Å; V369-V385 HydrophobicContact CG1-CB 4.23Å; V369-V385 HydrophobicContact CG2-CB 3.78Å; V369-V385 HydrophobicContact CG2-CG2 3.91Å; V369-L388 HydrophobicContact CG2-CD1 4.34Å; V369-T390 HydrophobicContact CG2-CG2 4.01Å; V369-Q392 PolarHBondContact N-O 3.28Å; V369-I393 CarbonylContact O-C 3.57Å; V369-I393 VanDerWaalsContact O-CA 3.32Å; V369-I393 WeakPolarHBondContact O-CA 3.34Å; V369-I393 WeakPolarHBondContact O-CG1 3.41Å; V369-K394 PolarHBondContact O-N 2.68Å
370S98.8Very high98.1Very high3 Ų325.7 Ų25.72%0.02116%0.161CC..EExtended strand (participates in β ladder)trans-131.3142.9-172.2-176.90000113L342 K394L342-S370 PolarHBondContact O-N 3.08Å; S370-K394 WeakPolarHBondContact CA-O 3.48Å; S370-K394 WeakPolarHBondContact OG-CE 3.46Å; S370-K394 WeakPolarHBondContact OG-CG 3.15Å
371H98.4Very high98.1Very high3 Ų326.2 Ų26.21%0.01416%0.163CC..  trans-68.6-176158.270.8159.9000112.7E210 E375 I381 K394 G396 R403E210-H371 IonicContact OE1-CE1 2.97Å; E210-H371 PolarHBondContact OE1-CE1 3.19Å; E210-H371 IonicContact OE1-NE2 3.25Å; E210-H371 IonicContact OE2-CE1 2.83Å; E210-H371 PolarHBondContact OE2-CE1 3.5Å; E210-H371 IonicContact OE2-NE2 3.08Å; E210-H371 PolarHBondContact OE2-NE2 2.81Å; H371-E375 HydrophobicContact CB-CG 3.82Å; H371-I381 HydrophobicContact CB-CD1 3.82Å; H371-K394 PolarHBondContact CD2-O 3.41Å; H371-K394 VanDerWaalsContact CD2-O 3.25Å; H371-K394 PolarHBondContact N-O 2.79Å; H371-G396 VanDerWaalsContact CE1-CA 3.45Å; H371-G396 WeakPolarHBondContact CE1-CA 3.37Å; H371-G396 PolarHBondContact CE1-N 3.43Å; H371-G396 PolarHBondContact ND1-N 3.09Å; H371-R403 PolarHBondContact ND1-NH1 2.89Å
372R97.3Very high98.2Very high5 Ų523.3 Ų23.32%0.01915%0.15CC..  trans-118164.4159.1-53-61.6-66.1-102.611.4110.4P36 S37 S40 E45 N345 G374 E375 R403P36-R372 HydrophobicContact CB-CB 4.01Å; P36-R372 HydrophobicContact CB-CG 3.84Å; P36-R372 HydrophobicContact CG-CG 3.99Å; S37-R372 WeakPolarHBondContact O-CB 3.35Å; S40-R372 PolarHBondContact O-NH2 3.02Å; E45-R372 IonicContact OE1-CZ 2.99Å; E45-R372 IonicContact OE1-NH1 3.3Å; E45-R372 IonicContact OE1-NH2 3.66Å; E45-R372 PolarHBondContact OE1-NH2 2.78Å; E45-R372 IonicContact OE2-CZ 3.89Å; E45-R372 IonicContact OE2-NH1 2.69Å; E45-R372 PolarHBondContact OE2-NH1 3.26Å; E45-R372 IonicContact OE2-NH2 3.98Å; E45-R372 PolarHBondContact OE2-NH2 3.29Å; E45-R372 VanDerWaalsContact OE2-NH2 3.08Å; N345-R372 PolarHBondContact ND2-NH1 2.86Å; N345-R372 VanDerWaalsContact OD1-CD 3.26Å; N345-R372 WeakPolarHBondContact OD1-CD 3.49Å; N345-R372 WeakPolarHBondContact OD1-CG 3.42Å; N345-R372 PolarHBondContact OD1-NH1 2.92Å; R372-G374 VanDerWaalsContact C-N 3.34Å; R372-G374 PolarHBondContact O-N 2.99Å; R372-E375 WeakPolarHBondContact O-CG 3.25Å; R372-R403 PolarHBondContact O-NH1 2.91Å
373S93.1Very high98.2Very high3 Ų319.4 Ų19.42%0.02112%0.117CC..SBendtrans-64-34.717649.70000113.2S14 A39 H158 E210 R403S14-S373 PolarHBondContact OG-O 3.32Å; A39-S373 WeakPolarHBondContact CB-OG 3.4Å; A39-S373 PolarHBondContact N-OG 2.79Å; H158-S373 WeakPolarHBondContact NE2-CB 3.32Å; E210-S373 WeakPolarHBondContact OE1-CA 3.39Å; E210-S373 WeakPolarHBondContact OE1-CB 3.47Å; S373-R403 PolarHBondContact O-NH2 3.28Å
374G96.3Very high98.3Very high0 Ų015.8 Ų15.80%010%0.098CC..BIsolated β-bridgetrans-90.793.3162.300000110.9P36 S37 R372P36-G374 CarbonylContact C-O 3.57Å; P36-G374 WeakPolarHBondContact CA-O 3.18Å; P36-G374 WeakPolarHBondContact CB-O 3.21Å; S37-G374 PolarHBondContact N-O 2.63Å; S37-G374 CarbonylContact O-C 3.46Å; S37-G374 WeakPolarHBondContact O-CA 3.4Å; S37-G374 PolarHBondContact O-N 2.94Å; R372-G374 VanDerWaalsContact C-N 3.34Å; R372-G374 PolarHBondContact O-N 2.99Å
375E98.4Very high98.4Very high6 Ų612.5 Ų12.53%0.0286%0.063CC..  trans-101.3175.2176.2-106.1-71.2-170.900112.2D13 S14 H371 R372 E402 R403 K406D13-E375 CarbonylContact C-O 3.54Å; D13-E375 WeakPolarHBondContact CA-O 3.36Å; S14-E375 WeakPolarHBondContact CB-O 3.44Å; S14-E375 PolarHBondContact N-O 3.1Å; S14-E375 PolarHBondContact OG-N 3.2Å; S14-E375 PolarHBondContact OG-O 3.15Å; H371-E375 HydrophobicContact CB-CG 3.82Å; R372-E375 WeakPolarHBondContact O-CG 3.25Å; E375-E402 HydrophobicContact CB-CB 3.91Å; E375-E402 HydrophobicContact CB-CG 3.66Å; E375-R403 VanDerWaalsContact CB-NH1 3.31Å; E375-K406 VanDerWaalsContact CD-CE 3.4Å; E375-K406 WeakPolarHBondContact OE1-CE 3.43Å; E375-K406 IonicContact OE1-NZ 2.89Å; E375-K406 PolarHBondContact OE1-NZ 3.49Å; E375-K406 IonicContact OE2-NZ 3.77Å; E375-K406 PolarHBondContact OE2-NZ 3.35Å
376T98.8Very high98.4Very high4 Ų411.3 Ų11.33%0.0256%0.059CC..  trans-124.7-178.5175.667.50000109.4I11 T19 A34 D378 E402 K406I11-T376 HydrophobicContact CD1-CG2 4.46Å; T19-T376 HydrophobicContact CG2-CG2 3.92Å; A34-T376 HydrophobicContact CB-CG2 3.87Å; T376-D378 PolarHBondContact O-N 3.19Å; T376-D378 VanDerWaalsContact OG1-CB 3.26Å; T376-D378 WeakPolarHBondContact OG1-CB 3.38Å; T376-D378 PolarHBondContact OG1-N 3.36Å; T376-D378 VanDerWaalsContact OG1-N 3.16Å; T376-E402 WeakPolarHBondContact O-CB 3.31Å; T376-K406 PolarHBondContact O-NZ 2.86Å
377E98.7Very high98.4Very high126 Ų12611 Ų1159%0.5896%0.056SC*.SBendtrans-71.9-8.6169.766.1-92.4-124.800113.7T379E377-T379 PolarHBondContact O-N 3.48Å
378D98.9Very high98.4Very high19 Ų1911 Ų1110%0.1026%0.056CC..  trans-60.5136.5-179.7-161.9-50.8000110.9A33 A34 K120 T376 F380 K406A33-D378 WeakPolarHBondContact CA-OD2 3.38Å; A34-D378 HydrophobicContact CB-CB 4.32Å; A34-D378 PolarHBondContact N-OD2 3.31Å; K120-D378 IonicContact NZ-OD1 3.69Å; K120-D378 PolarHBondContact NZ-OD1 2.98Å; K120-D378 IonicContact NZ-OD2 3.94Å; K120-D378 PolarHBondContact NZ-OD2 3.1Å; T376-D378 PolarHBondContact O-N 3.19Å; T376-D378 VanDerWaalsContact OG1-CB 3.26Å; T376-D378 WeakPolarHBondContact OG1-CB 3.38Å; T376-D378 PolarHBondContact OG1-N 3.36Å; T376-D378 VanDerWaalsContact OG1-N 3.16Å; D378-F380 VanDerWaalsContact OD1-CB 3.26Å; D378-F380 WeakPolarHBondContact OD1-CB 3.37Å; D378-F380 PolarHBondContact OD1-N 3.01Å; D378-K406 WeakPolarHBondContact O-CD 3.21Å; D378-K406 WeakPolarHBondContact O-CE 3.49Å; D378-K406 PolarHBondContact O-NZ 2.91Å
379T98.9Very high98.3Very high36 Ų3611 Ų1122%0.2216%0.056CC..  trans-107.29.6-175.752.10000113.6E377 I381 A382 A405 Q409E377-T379 PolarHBondContact O-N 3.48Å; T379-I381 VanDerWaalsContact C-N 3.25Å; T379-I381 PolarHBondContact O-N 2.73Å; T379-A382 VanDerWaalsContact O-CB 3.27Å; T379-A382 WeakPolarHBondContact O-CB 3.06Å; T379-A382 PolarHBondContact O-N 3.46Å; T379-A405 HydrophobicContact CG2-CB 3.78Å; T379-A405 VanDerWaalsContact CG2-O 3.28Å; T379-A405 WeakPolarHBondContact CG2-O 3.33Å; T379-Q409 HydrophobicContact CG2-CB 4.1Å
380F98.9Very high98.3Very high6 Ų611.1 Ų11.13%0.0266%0.056CC..Hα-helixtrans-48.5-42.8-173-174.2-89.4000114L116 C119 L130 I134 V350 D378 A382 D383 L384L116-F380 HydrophobicContact CB-CD2 4.43Å; L116-F380 HydrophobicContact CD2-CD1 3.45Å; L116-F380 VanDerWaalsContact CD2-CD1 3.45Å; L116-F380 HydrophobicContact CD2-CD2 3.73Å; L116-F380 HydrophobicContact CD2-CE1 3.38Å; L116-F380 HydrophobicContact CD2-CE2 3.68Å; L116-F380 HydrophobicContact CD2-CG 3.63Å; L116-F380 HydrophobicContact CD2-CZ 3.51Å; C119-F380 HydrophobicContact CB-CE2 3.92Å; C119-F380 HydrophobicContact CB-CZ 4.31Å; L130-F380 HydrophobicContact CD1-CE2 4.32Å; L130-F380 HydrophobicContact CD2-CD2 3.86Å; L130-F380 HydrophobicContact CD2-CE2 4.2Å; I134-F380 HydrophobicContact CD1-CE1 4.38Å; I134-F380 HydrophobicContact CD1-CE2 4.2Å; I134-F380 HydrophobicContact CD1-CZ 3.92Å; V350-F380 HydrophobicContact CG1-CZ 4.33Å; V350-F380 HydrophobicContact CG2-CE1 4.28Å; V350-F380 HydrophobicContact CG2-CE2 4.48Å; V350-F380 HydrophobicContact CG2-CZ 3.73Å; D378-F380 VanDerWaalsContact OD1-CB 3.26Å; D378-F380 WeakPolarHBondContact OD1-CB 3.37Å; D378-F380 PolarHBondContact OD1-N 3.01Å; F380-A382 PolarHBondContact O-N 3.11Å; F380-D383 PolarHBondContact O-N 3.34Å; F380-L384 HydrophobicContact CD1-CB 4.19Å; F380-L384 HydrophobicContact CD1-CD2 4.42Å; F380-L384 HydrophobicContact CE1-CB 4.08Å; F380-L384 HydrophobicContact CE1-CD1 4.02Å; F380-L384 HydrophobicContact CE1-CD2 4.13Å; F380-L384 HydrophobicContact CE1-CG 4.3Å; F380-L384 WeakPolarHBondContact O-CB 3.31Å; F380-L384 PolarHBondContact O-N 2.91Å
381I98.9Very high98.3Very high11 Ų1111 Ų116%0.0566%0.055CC..Hα-helixtrans-68-21-176.463.6171.3000113.8V369 H371 T379 L384 V385 I393 K406V369-I381 HydrophobicContact CG1-CB 3.85Å; V369-I381 HydrophobicContact CG1-CG2 4.31Å; H371-I381 HydrophobicContact CB-CD1 3.82Å; T379-I381 VanDerWaalsContact C-N 3.25Å; T379-I381 PolarHBondContact O-N 2.73Å; I381-L384 HydrophobicContact CG2-CD2 4.47Å; I381-V385 WeakPolarHBondContact O-CG1 3.43Å; I381-V385 PolarHBondContact O-N 2.88Å; I381-I393 HydrophobicContact CD1-CD1 4.46Å; I381-I393 HydrophobicContact CG1-CD1 4.39Å; I381-K406 HydrophobicContact CD1-CG 3.99Å; I381-K406 HydrophobicContact CG1-CG 3.57Å
382A98.9Very high98.4Very high0 Ų010.8 Ų10.80%06%0.055CC..Hα-helixtrans-68.8-44.1172.100000111.3T379 F380 V385 V386 K406 Q409 L410T379-A382 VanDerWaalsContact O-CB 3.27Å; T379-A382 WeakPolarHBondContact O-CB 3.06Å; T379-A382 PolarHBondContact O-N 3.46Å; F380-A382 PolarHBondContact O-N 3.11Å; A382-V385 VanDerWaalsContact O-CG1 3.28Å; A382-V385 WeakPolarHBondContact O-CG1 3.46Å; A382-V386 WeakPolarHBondContact O-CG2 3.37Å; A382-K406 HydrophobicContact CB-CB 4.21Å; A382-K406 WeakPolarHBondContact CB-O 3.25Å; A382-Q409 HydrophobicContact CB-CB 3.74Å; A382-Q409 HydrophobicContact CB-CG 3.66Å; A382-L410 HydrophobicContact CB-CD2 4.14Å; A382-L410 HydrophobicContact CB-CG 3.88Å; A382-L410 WeakPolarHBondContact O-CD2 3.26Å
383D98.9Very high98.4Very high6 Ų610.6 Ų10.63%0.0325%0.054CC..Hα-helixtrans-70.2-35.5173.2-75.3-99.2000111.7L130 Y131 I134 F380 V386 G387 Q409L130-D383 HydrophobicContact CB-CB 4.04Å; L130-D383 WeakPolarHBondContact CB-OD1 3.18Å; L130-D383 HydrophobicContact CD2-CB 3.72Å; L130-D383 HydrophobicContact CG-CB 3.71Å; Y131-D383 WeakPolarHBondContact CA-O 3.47Å; Y131-D383 WeakPolarHBondContact CB-O 3.42Å; Y131-D383 PolarHBondContact N-OD1 3.1Å; I134-D383 HydrophobicContact CD1-CB 4.22Å; F380-D383 PolarHBondContact O-N 3.34Å; D383-V386 PolarHBondContact O-N 3.06Å; D383-G387 PolarHBondContact O-N 3.23Å; D383-Q409 WeakPolarHBondContact OD2-CG 3.48Å; D383-Q409 PolarHBondContact OD2-NE2 3.34Å
384L98.9Very high98.7Very high1 Ų110.6 Ų10.61%0.0055%0.053CC..Hα-helixtrans-61-50.7178.5-175.665.5000112.2I134 L342 V344 L354 V369 F380 I381 V386 G387 L388I134-L384 HydrophobicContact CD1-CB 4.28Å; I134-L384 HydrophobicContact CD1-CD1 4.26Å; I134-L384 HydrophobicContact CG2-CD1 3.91Å; L342-L384 HydrophobicContact CD2-CD2 3.9Å; V344-L384 HydrophobicContact CG1-CD2 3.46Å; V344-L384 VanDerWaalsContact CG1-CD2 3.46Å; L354-L384 HydrophobicContact CD2-CD1 4.15Å; V369-L384 HydrophobicContact CG1-CD2 4.08Å; F380-L384 HydrophobicContact CD1-CB 4.19Å; F380-L384 HydrophobicContact CD1-CD2 4.42Å; F380-L384 HydrophobicContact CE1-CB 4.08Å; F380-L384 HydrophobicContact CE1-CD1 4.02Å; F380-L384 HydrophobicContact CE1-CD2 4.13Å; F380-L384 HydrophobicContact CE1-CG 4.3Å; F380-L384 WeakPolarHBondContact O-CB 3.31Å; F380-L384 PolarHBondContact O-N 2.91Å; I381-L384 HydrophobicContact CG2-CD2 4.47Å; L384-V386 VanDerWaalsContact C-N 3.28Å; L384-V386 PolarHBondContact O-N 3.4Å; L384-G387 PolarHBondContact O-N 2.91Å; L384-L388 HydrophobicContact CD1-CD1 3.69Å; L384-L388 HydrophobicContact CD1-CG 3.99Å; L384-L388 HydrophobicContact CD2-CD1 4.45Å; L384-L388 HydrophobicContact CG-CD1 3.76Å; L384-L388 HydrophobicContact CG-CG 4.33Å; L384-L388 VanDerWaalsContact O-CB 3.26Å; L384-L388 WeakPolarHBondContact O-CB 3.37Å; L384-L388 WeakPolarHBondContact O-CG 3.2Å; L384-L388 PolarHBondContact O-N 3.07Å
385V98.9Very high98.8Very high0 Ų010.6 Ų10.60%05%0.053CC..Hα-helixtrans-62.9-37.7-177.866.80000112.1P146 V369 I381 A382 C389 T390 Q392 I393 L410P146-V385 HydrophobicContact CB-CG1 4.36Å; P146-V385 HydrophobicContact CB-CG2 3.7Å; P146-V385 HydrophobicContact CG-CG1 3.72Å; P146-V385 HydrophobicContact CG-CG2 4.01Å; V369-V385 HydrophobicContact CB-CB 3.83Å; V369-V385 HydrophobicContact CB-CG2 4Å; V369-V385 HydrophobicContact CG1-CB 4.23Å; V369-V385 HydrophobicContact CG2-CB 3.78Å; V369-V385 HydrophobicContact CG2-CG2 3.91Å; I381-V385 WeakPolarHBondContact O-CG1 3.43Å; I381-V385 PolarHBondContact O-N 2.88Å; A382-V385 VanDerWaalsContact O-CG1 3.28Å; A382-V385 WeakPolarHBondContact O-CG1 3.46Å; V385-C389 PolarHBondContact O-N 3.37Å; V385-C389 VanDerWaalsContact O-N 3.17Å; V385-T390 VanDerWaalsContact CG2-OG1 3.29Å; V385-T390 WeakPolarHBondContact CG2-OG1 3.49Å; V385-T390 PolarHBondContact O-N 2.89Å; V385-Q392 WeakPolarHBondContact CG2-O 3.42Å; V385-I393 HydrophobicContact CB-CB 4.38Å; V385-I393 HydrophobicContact CB-CD1 4.36Å; V385-I393 HydrophobicContact CG1-CB 4.25Å; V385-I393 HydrophobicContact CG1-CD1 3.88Å; V385-I393 HydrophobicContact CG2-CB 4.06Å; V385-L410 HydrophobicContact CG1-CD2 3.95Å
386V98.9Very high98.8Very high0 Ų010.3 Ų10.30%05%0.052CC..Hα-helixtrans-68.5-47.3177174.30000110.4Y131 V143 I144 L145 A382 D383 L384 L388 C389 L410 I413Y131-V386 HydrophobicContact CD2-CG1 4.05Å; Y131-V386 HydrophobicContact CG-CG1 4.13Å; V143-V386 HydrophobicContact CB-CG1 3.71Å; V143-V386 HydrophobicContact CG1-CG1 4.25Å; V143-V386 HydrophobicContact CG2-CG1 4.15Å; I144-V386 WeakPolarHBondContact O-CA 3.19Å; L145-V386 HydrophobicContact CD2-CG2 4.03Å; A382-V386 WeakPolarHBondContact O-CG2 3.37Å; D383-V386 PolarHBondContact O-N 3.06Å; L384-V386 VanDerWaalsContact C-N 3.28Å; L384-V386 PolarHBondContact O-N 3.4Å; V386-L388 VanDerWaalsContact C-N 3.34Å; V386-L388 PolarHBondContact O-N 2.97Å; V386-C389 PolarHBondContact O-N 3.47Å; V386-L410 HydrophobicContact CG2-CD2 3.56Å; V386-I413 HydrophobicContact CG1-CG2 4.01Å; V386-I413 HydrophobicContact CG2-CD1 4.31Å; V386-I413 HydrophobicContact CG2-CG2 4.17Å
387G98.8Very high98.8Very high0 Ų010.1 Ų10.10%05%0.051CC..Hα-helixtrans-64.6-37.5-179.900000113.2Y131 A135 N140 D383 L384 C389Y131-G387 VanDerWaalsContact O-CA 3.23Å; Y131-G387 WeakPolarHBondContact O-CA 3.34Å; A135-G387 VanDerWaalsContact CA-O 3.3Å; A135-G387 WeakPolarHBondContact CA-O 3.39Å; A135-G387 WeakPolarHBondContact CB-O 3.44Å; N140-G387 PolarHBondContact ND2-O 3.32Å; D383-G387 PolarHBondContact O-N 3.23Å; L384-G387 PolarHBondContact O-N 2.91Å; G387-C389 VanDerWaalsContact C-N 3.28Å; G387-C389 PolarHBondContact O-N 3.14Å
388L98.8Very high98.8Very high1 Ų14.9 Ų4.91%0.0053%0.028CC..Hα-helixtrans-77.5-9.8176.6-75.1-179.3000114.1I134 A138 N140 L342 L354 C357 Q361 V369 L384 V386 T390I134-L388 HydrophobicContact CG2-CG 4.47Å; A138-L388 HydrophobicContact CB-CD2 3.9Å; N140-L388 VanDerWaalsContact ND2-C 3.34Å; N140-L388 PolarHBondContact ND2-O 3.02Å; L342-L388 HydrophobicContact CD1-CD1 3.97Å; L354-L388 HydrophobicContact CD2-CD1 4.42Å; L354-L388 HydrophobicContact CD2-CD2 3.4Å; L354-L388 VanDerWaalsContact CD2-CD2 3.4Å; L354-L388 HydrophobicContact CD2-CG 4.09Å; C357-L388 HydrophobicContact CB-CD1 4.03Å; C357-L388 HydrophobicContact CB-CD2 4.04Å; Q361-L388 PolarHBondContact NE2-O 2.68Å; V369-L388 HydrophobicContact CG2-CD1 4.34Å; L384-L388 HydrophobicContact CD1-CD1 3.69Å; L384-L388 HydrophobicContact CD1-CG 3.99Å; L384-L388 HydrophobicContact CD2-CD1 4.45Å; L384-L388 HydrophobicContact CG-CD1 3.76Å; L384-L388 HydrophobicContact CG-CG 4.33Å; L384-L388 VanDerWaalsContact O-CB 3.26Å; L384-L388 WeakPolarHBondContact O-CB 3.37Å; L384-L388 WeakPolarHBondContact O-CG 3.2Å; L384-L388 PolarHBondContact O-N 3.07Å; V386-L388 VanDerWaalsContact C-N 3.34Å; V386-L388 PolarHBondContact O-N 2.97Å; L388-T390 HydrophobicContact CB-CG2 3.41Å; L388-T390 VanDerWaalsContact CB-CG2 3.41Å; L388-T390 HydrophobicContact CD1-CG2 4.24Å; L388-T390 HydrophobicContact CG-CG2 4.47Å; L388-T390 PolarHBondContact O-N 3.02Å
389C98.6Very high98.8Very high1 Ų15.5 Ų5.51%0.0073%0.034CC..THydrogen-bonded Turntrans5338.3-177.9-60.10000113E142 V143 I144 V385 V386 G387 G391 P431 L432E142-C389 PolarHBondContact O-SG 3.12Å; V143-C389 VanDerWaalsContact CA-SG 3.57Å; I144-C389 HydrophobicContact CB-CB 4.4Å; I144-C389 HydrophobicContact CG1-CB 4.12Å; V385-C389 PolarHBondContact O-N 3.37Å; V385-C389 VanDerWaalsContact O-N 3.17Å; V386-C389 PolarHBondContact O-N 3.47Å; G387-C389 VanDerWaalsContact C-N 3.28Å; G387-C389 PolarHBondContact O-N 3.14Å; C389-G391 VanDerWaalsContact C-N 3.33Å; C389-P431 WeakPolarHBondContact O-CG 3.42Å; C389-L432 HydrophobicContact CB-CD1 3.75Å; C389-L432 HydrophobicContact CB-CD2 4.17Å; C389-L432 HydrophobicContact CB-CG 4.08Å
390T98.8Very high98.8Very high2 Ų27.6 Ų7.61%0.0124%0.037CC..  trans-79.3-21.2-172.882.90000113.2V367 V369 V385 L388 Q392V367-T390 HydrophobicContact CB-CG2 3.92Å; V367-T390 HydrophobicContact CG1-CG2 3.99Å; V367-T390 WeakPolarHBondContact O-CB 3.36Å; V367-T390 PolarHBondContact O-OG1 3.34Å; V369-T390 HydrophobicContact CG2-CG2 4.01Å; V385-T390 VanDerWaalsContact CG2-OG1 3.29Å; V385-T390 WeakPolarHBondContact CG2-OG1 3.49Å; V385-T390 PolarHBondContact O-N 2.89Å; L388-T390 HydrophobicContact CB-CG2 3.41Å; L388-T390 VanDerWaalsContact CB-CG2 3.41Å; L388-T390 HydrophobicContact CD1-CG2 4.24Å; L388-T390 HydrophobicContact CG-CG2 4.47Å; L388-T390 PolarHBondContact O-N 3.02Å; T390-Q392 VanDerWaalsContact C-N 3.29Å; T390-Q392 PolarHBondContact O-N 3.38Å; T390-Q392 PolarHBondContact OG1-O 3.08Å; T390-Q392 VanDerWaalsContact OG1-O 3.13Å
391G98.8Very high98.8Very high0 Ų011.6 Ų11.60%07%0.066CC..SBendtrans82.2-1174.300000115.1P146 V147 C389 A424 F428P146-G391 CarbonylContact C-O 3.43Å; P146-G391 VanDerWaalsContact CA-C 3.47Å; P146-G391 WeakPolarHBondContact CA-O 3.36Å; V147-G391 PolarHBondContact N-O 3.23Å; C389-G391 VanDerWaalsContact C-N 3.33Å; G391-A424 WeakPolarHBondContact O-CB 3.33Å; G391-F428 WeakPolarHBondContact O-CB 3.39Å
392Q98.9Very high98.8Very high0 Ų012 Ų120%07%0.068CC..EExtended strand (participates in β ladder)trans-155.3140.2-178.849.3-176.9-55.200112.2V147 V367 M368 V369 V385 T390 F428V147-Q392 WeakPolarHBondContact O-CA 3.4Å; V367-Q392 WeakPolarHBondContact O-CG 3.39Å; M368-Q392 HydrophobicContact CB-CG 4.01Å; M368-Q392 HydrophobicContact CG-CG 4.35Å; V369-Q392 PolarHBondContact N-O 3.28Å; V385-Q392 WeakPolarHBondContact CG2-O 3.42Å; T390-Q392 VanDerWaalsContact C-N 3.29Å; T390-Q392 PolarHBondContact O-N 3.38Å; T390-Q392 PolarHBondContact OG1-O 3.08Å; T390-Q392 VanDerWaalsContact OG1-O 3.13Å; Q392-F428 HydrophobicContact CB-CB 4.36Å; Q392-F428 HydrophobicContact CB-CD2 4.06Å; Q392-F428 HydrophobicContact CG-CD2 4.27Å; Q392-F428 PolarHBondContact NE2-O 3.29Å
393I98.9Very high98.7Very high0 Ų012 Ų120%07%0.068CC..EExtended strand (participates in β ladder)trans-136.6136.1177.8-174.6168.6000109.9P146 V147 A149 V369 I381 V385 T395 L410P146-I393 HydrophobicContact CB-CB 4.24Å; P146-I393 HydrophobicContact CB-CG2 3.88Å; P146-I393 HydrophobicContact CG-CB 4.19Å; P146-I393 HydrophobicContact CG-CG2 3.54Å; V147-I393 PolarHBondContact O-N 2.98Å; V147-I393 VanDerWaalsContact O-N 3.1Å; A149-I393 PolarHBondContact N-O 2.8Å; V369-I393 CarbonylContact O-C 3.57Å; V369-I393 VanDerWaalsContact O-CA 3.32Å; V369-I393 WeakPolarHBondContact O-CA 3.34Å; V369-I393 WeakPolarHBondContact O-CG1 3.41Å; I381-I393 HydrophobicContact CD1-CD1 4.46Å; I381-I393 HydrophobicContact CG1-CD1 4.39Å; V385-I393 HydrophobicContact CB-CB 4.38Å; V385-I393 HydrophobicContact CB-CD1 4.36Å; V385-I393 HydrophobicContact CG1-CB 4.25Å; V385-I393 HydrophobicContact CG1-CD1 3.88Å; V385-I393 HydrophobicContact CG2-CB 4.06Å; I393-T395 HydrophobicContact CD1-CG2 3.85Å; I393-T395 HydrophobicContact CG1-CG2 4.04Å; I393-L410 HydrophobicContact CD1-CD1 4.35Å; I393-L410 HydrophobicContact CG2-CD1 4.02Å
394K98.8Very high98.7Very high3 Ų313.9 Ų13.91%0.0138%0.078CC..EExtended strand (participates in β ladder)trans-107.8117.1160.877.6176.6-162.4172.80109.7A149 E167 M169 D245 E293 L341 M368 V369 S370 H371A149-K394 HydrophobicContact CB-CB 4.09Å; E167-K394 IonicContact OE1-NZ 3.89Å; E167-K394 IonicContact OE2-NZ 2.67Å; E167-K394 PolarHBondContact OE2-NZ 2.95Å; M169-K394 HydrophobicContact CE-CD 4.5Å; M169-K394 HydrophobicContact SD-CB 4.13Å; M169-K394 HydrophobicContact SD-CD 4.17Å; D245-K394 IonicContact OD2-NZ 3.98Å; E293-K394 IonicContact OE1-NZ 2.7Å; E293-K394 PolarHBondContact OE1-NZ 3.36Å; E293-K394 WeakPolarHBondContact OE2-CE 3.46Å; E293-K394 IonicContact OE2-NZ 2.84Å; E293-K394 PolarHBondContact OE2-NZ 2.91Å; L341-K394 HydrophobicContact CD1-CD 3.78Å; L341-K394 HydrophobicContact CD1-CG 4.13Å; M368-K394 HydrophobicContact CG-CB 4.39Å; M368-K394 HydrophobicContact CG-CG 4.41Å; M368-K394 HydrophobicContact SD-CB 3.75Å; M368-K394 HydrophobicContact SD-CD 3.91Å; M368-K394 HydrophobicContact SD-CG 3.91Å; V369-K394 PolarHBondContact O-N 2.68Å; S370-K394 WeakPolarHBondContact CA-O 3.48Å; S370-K394 WeakPolarHBondContact OG-CE 3.46Å; S370-K394 WeakPolarHBondContact OG-CG 3.15Å; H371-K394 PolarHBondContact CD2-O 3.41Å; H371-K394 VanDerWaalsContact CD2-O 3.25Å; H371-K394 PolarHBondContact N-O 2.79Å
395T98.7Very high98.7Very high0 Ų014.8 Ų14.80%09%0.085CC..  trans-14135.8179.5-1750000112.4I393 R403 K406 Y407I393-T395 HydrophobicContact CD1-CG2 3.85Å; I393-T395 HydrophobicContact CG1-CG2 4.04Å; T395-R403 WeakPolarHBondContact O-CA 3.49Å; T395-R403 WeakPolarHBondContact O-CB 3.14Å; T395-R403 WeakPolarHBondContact O-CD 3.47Å; T395-K406 HydrophobicContact CG2-CB 3.81Å; T395-Y407 HydrophobicContact CG2-CD1 3.72Å; T395-Y407 HydrophobicContact CG2-CD2 4.24Å; T395-Y407 HydrophobicContact CG2-CE1 3.22Å; T395-Y407 HydrophobicContact CG2-CE2 3.8Å; T395-Y407 HydrophobicContact CG2-CG 4.21Å; T395-Y407 PolarHBondContact N-OH 3.39Å
396G98.4Very high98.7Very high0 Ų014.8 Ų14.80%09%0.085CC..  trans91.2-174.3173.500000114.9F150 H371 Y407F150-G396 WeakPolarHBondContact CA-O 3.5Å; H371-G396 VanDerWaalsContact CE1-CA 3.45Å; H371-G396 WeakPolarHBondContact CE1-CA 3.37Å; H371-G396 PolarHBondContact CE1-N 3.43Å; H371-G396 PolarHBondContact ND1-N 3.09Å; G396-Y407 PolarHBondContact N-OH 3.31Å; G396-Y407 WeakPolarHBondContact O-CE2 3.5Å; G396-Y407 PolarHBondContact O-OH 3.28Å
397A98.8Very high98.7Very high0 Ų014.8 Ų14.80%09%0.085CC..  trans-65165.2174.400000111.8N151 Y189 E210 G211 C399 R403N151-A397 WeakPolarHBondContact O-CA 3.49Å; N151-A397 WeakPolarHBondContact O-CB 3.45Å; N151-A397 PolarHBondContact O-N 3.48Å; Y189-A397 HydrophobicContact CE2-CB 4.09Å; E210-A397 WeakPolarHBondContact O-CB 3.24Å; E210-A397 PolarHBondContact O-N 2.99Å; G211-A397 WeakPolarHBondContact O-CB 3.48Å; A397-C399 HydrophobicContact CB-CB 3.96Å; A397-C399 PolarHBondContact O-N 3.23Å; A397-R403 WeakPolarHBondContact O-CB 3.44Å
398P98.6Very high98.7Very high16 Ų1617.8 Ų17.810%0.10410%0.101CC..SBendtrans-72.346.8160.634.3-36.5000111.2F150 A186 Y189 L404F150-P398 HydrophobicContact CD1-CB 4.39Å; F150-P398 HydrophobicContact CD1-CG 4.43Å; F150-P398 HydrophobicContact CE1-CB 4.43Å; A186-P398 HydrophobicContact CB-CB 4.38Å; Y189-P398 HydrophobicContact CD1-CG 4.05Å; Y189-P398 HydrophobicContact CD2-CG 4.33Å; Y189-P398 HydrophobicContact CG-CG 3.76Å; P398-L404 HydrophobicContact CB-CD2 4.45Å
399C98.5Very high98.8Very high33 Ų3319.5 Ų19.522%0.22311%0.109CC..  trans-150150.6-177.9-174.70000108.8Y189 A397 R403Y189-C399 HydrophobicContact CE1-CB 3.97Å; Y189-C399 WeakPolarHBondContact OH-CB 3.36Å; A397-C399 HydrophobicContact CB-CB 3.96Å; A397-C399 PolarHBondContact O-N 3.23Å; C399-R403 WeakPolarHBondContact O-CB 3.19Å; C399-R403 VanDerWaalsContact O-CG 3.25Å; C399-R403 WeakPolarHBondContact O-CG 3.35Å
400R98.3Very high98.8Very high79 Ų7919.5 Ų19.530%0.29811%0.109SC..SBendtrans66132.3-173.4-45.6174.555.3104.45.6113.2S14 D209 E402 R403 L404S14-R400 PolarHBondContact O-NH2 3.19Å; D209-R400 PolarHBondContact O-NE 3.08Å; R400-E402 VanDerWaalsContact CB-OE1 3.3Å; R400-E402 WeakPolarHBondContact CB-OE1 3.49Å; R400-E402 WeakPolarHBondContact CB-OE2 3.4Å; R400-E402 IonicContact CZ-OE1 3.16Å; R400-E402 IonicContact NE-OE1 2.62Å; R400-E402 PolarHBondContact NE-OE1 3.48Å; R400-E402 IonicContact NE-OE2 3.62Å; R400-E402 IonicContact NH2-OE1 2.91Å; R400-E402 PolarHBondContact O-N 2.67Å; R400-R403 HydrophobicContact CB-CG 4.26Å; R400-R403 WeakPolarHBondContact O-CB 3.32Å; R400-R403 PolarHBondContact O-N 2.95Å; R400-R403 VanDerWaalsContact O-N 3.09Å; R400-L404 PolarHBondContact O-N 3.47Å; R400-L404 VanDerWaalsContact O-N 3.08Å
401S98.8Very high98.8Very high91 Ų9121.8 Ų21.864%0.63612%0.121SC*.Hα-helixtrans-74-24-164.3-65.50000114.2R403 L404 A405S401-R403 PolarHBondContact O-N 3.2Å; S401-L404 PolarHBondContact O-N 2.88Å; S401-A405 WeakPolarHBondContact O-CB 3.18Å; S401-A405 PolarHBondContact O-N 2.89Å
402E98.7Very high98.8Very high20 Ų2028.1 Ų28.19%0.09315%0.145CC..Hα-helixtrans-63.1-22.6171.478-78.5-172.900112.1S14 E375 T376 R400 K406S14-E402 VanDerWaalsContact CB-CG 3.48Å; E375-E402 HydrophobicContact CB-CB 3.91Å; E375-E402 HydrophobicContact CB-CG 3.66Å; T376-E402 WeakPolarHBondContact O-CB 3.31Å; R400-E402 VanDerWaalsContact CB-OE1 3.3Å; R400-E402 WeakPolarHBondContact CB-OE1 3.49Å; R400-E402 WeakPolarHBondContact CB-OE2 3.4Å; R400-E402 IonicContact CZ-OE1 3.16Å; R400-E402 IonicContact NE-OE1 2.62Å; R400-E402 PolarHBondContact NE-OE1 3.48Å; R400-E402 IonicContact NE-OE2 3.62Å; R400-E402 IonicContact NH2-OE1 2.91Å; R400-E402 PolarHBondContact O-N 2.67Å; E402-K406 VanDerWaalsContact O-CD 3.24Å; E402-K406 WeakPolarHBondContact O-CD 3.45Å; E402-K406 WeakPolarHBondContact O-CE 3.11Å; E402-K406 PolarHBondContact O-NZ 3.17Å
403R98.8Very high98.8Very high0 Ų028.1 Ų28.10%015%0.145CC..Hα-helixtrans-87.4-54.8173.9-43.5-51.7166.6-179.97.6109.9D209 H371 R372 S373 E375 T395 A397 C399 R400 S401 A405 K406 Y407D209-R403 PolarHBondContact O-NH2 3.47Å; H371-R403 PolarHBondContact ND1-NH1 2.89Å; R372-R403 PolarHBondContact O-NH1 2.91Å; S373-R403 PolarHBondContact O-NH2 3.28Å; E375-R403 VanDerWaalsContact CB-NH1 3.31Å; T395-R403 WeakPolarHBondContact O-CA 3.49Å; T395-R403 WeakPolarHBondContact O-CB 3.14Å; T395-R403 WeakPolarHBondContact O-CD 3.47Å; A397-R403 WeakPolarHBondContact O-CB 3.44Å; C399-R403 WeakPolarHBondContact O-CB 3.19Å; C399-R403 VanDerWaalsContact O-CG 3.25Å; C399-R403 WeakPolarHBondContact O-CG 3.35Å; R400-R403 HydrophobicContact CB-CG 4.26Å; R400-R403 WeakPolarHBondContact O-CB 3.32Å; R400-R403 PolarHBondContact O-N 2.95Å; R400-R403 VanDerWaalsContact O-N 3.09Å; S401-R403 PolarHBondContact O-N 3.2Å; R403-A405 PolarHBondContact O-N 3.23Å; R403-A405 VanDerWaalsContact O-N 3.16Å; R403-K406 PolarHBondContact O-N 2.9Å; R403-K406 VanDerWaalsContact O-N 3.08Å; R403-Y407 HydrophobicContact CB-CE2 4.46Å; R403-Y407 WeakPolarHBondContact O-CD2 3.35Å; R403-Y407 PolarHBondContact O-N 3.03Å
404L98.9Very high98.8Very high44 Ų4429.3 Ų29.323%0.2315%0.15CC..Hα-helixtrans-61-26.1-179.5-66.6171.4000112.7P398 R400 S401 K406 Y407 N408P398-L404 HydrophobicContact CB-CD2 4.45Å; R400-L404 PolarHBondContact O-N 3.47Å; R400-L404 VanDerWaalsContact O-N 3.08Å; S401-L404 PolarHBondContact O-N 2.88Å; L404-K406 VanDerWaalsContact C-N 3.28Å; L404-K406 PolarHBondContact O-N 2.93Å; L404-Y407 HydrophobicContact CD2-CD2 4.5Å; L404-Y407 PolarHBondContact O-N 2.8Å; L404-N408 WeakPolarHBondContact O-CB 3.17Å; L404-N408 PolarHBondContact O-N 2.68Å; L404-N408 PolarHBondContact O-ND2 2.87Å; L404-N408 VanDerWaalsContact O-ND2 3.12Å
405A98.9Very high98.8Very high20 Ų2037 Ų3717%0.16519%0.186CC..Hα-helixtrans-56.8-43.4174.800000111.5T379 S401 R403 Q409T379-A405 HydrophobicContact CG2-CB 3.78Å; T379-A405 VanDerWaalsContact CG2-O 3.28Å; T379-A405 WeakPolarHBondContact CG2-O 3.33Å; S401-A405 WeakPolarHBondContact O-CB 3.18Å; S401-A405 PolarHBondContact O-N 2.89Å; R403-A405 PolarHBondContact O-N 3.23Å; R403-A405 VanDerWaalsContact O-N 3.16Å; A405-Q409 WeakPolarHBondContact O-CB 3.23Å; A405-Q409 PolarHBondContact O-N 2.61Å
406K98.9Very high98.8Very high0 Ų042.5 Ų42.50%021%0.212CC..Hα-helixtrans-72.3-46.1178.9-72.865159173.10111E375 T376 D378 I381 A382 T395 E402 R403 L404 N408 Q409 L410E375-K406 VanDerWaalsContact CD-CE 3.4Å; E375-K406 WeakPolarHBondContact OE1-CE 3.43Å; E375-K406 IonicContact OE1-NZ 2.89Å; E375-K406 PolarHBondContact OE1-NZ 3.49Å; E375-K406 IonicContact OE2-NZ 3.77Å; E375-K406 PolarHBondContact OE2-NZ 3.35Å; T376-K406 PolarHBondContact O-NZ 2.86Å; D378-K406 WeakPolarHBondContact O-CD 3.21Å; D378-K406 WeakPolarHBondContact O-CE 3.49Å; D378-K406 PolarHBondContact O-NZ 2.91Å; I381-K406 HydrophobicContact CD1-CG 3.99Å; I381-K406 HydrophobicContact CG1-CG 3.57Å; A382-K406 HydrophobicContact CB-CB 4.21Å; A382-K406 WeakPolarHBondContact CB-O 3.25Å; T395-K406 HydrophobicContact CG2-CB 3.81Å; E402-K406 VanDerWaalsContact O-CD 3.24Å; E402-K406 WeakPolarHBondContact O-CD 3.45Å; E402-K406 WeakPolarHBondContact O-CE 3.11Å; E402-K406 PolarHBondContact O-NZ 3.17Å; R403-K406 PolarHBondContact O-N 2.9Å; R403-K406 VanDerWaalsContact O-N 3.08Å; L404-K406 VanDerWaalsContact C-N 3.28Å; L404-K406 PolarHBondContact O-N 2.93Å; K406-N408 VanDerWaalsContact C-N 3.34Å; K406-N408 PolarHBondContact O-N 3.04Å; K406-Q409 WeakPolarHBondContact O-CB 3.23Å; K406-Q409 PolarHBondContact O-N 2.78Å; K406-Q409 VanDerWaalsContact O-N 3.12Å; K406-L410 WeakPolarHBondContact O-CG 3.3Å; K406-L410 PolarHBondContact O-N 3.02Å
407Y98.9Very high98.8Very high0 Ų043.5 Ų43.50%022%0.218CC..Hα-helixtrans-61.6-41.3177-68-48000112.7P148 F150 F178 M182 T395 G396 R403 L404 Q409 L410 L411P148-Y407 HydrophobicContact CB-CD1 4.27Å; P148-Y407 HydrophobicContact CB-CE1 3.63Å; F150-Y407 HydrophobicContact CD1-CE1 4.08Å; F150-Y407 AromaticContact CD1-CE2 3.74Å; F150-Y407 HydrophobicContact CD1-CE2 3.74Å; F150-Y407 AromaticContact CD1-CZ 3.48Å; F150-Y407 VanDerWaalsContact CD1-CZ 3.48Å; F150-Y407 WeakPolarHBondContact CD1-OH 3.28Å; F150-Y407 HydrophobicContact CE1-CD1 4.02Å; F150-Y407 HydrophobicContact CE1-CD2 4.09Å; F150-Y407 AromaticContact CE1-CE1 3.62Å; F150-Y407 HydrophobicContact CE1-CE1 3.62Å; F150-Y407 AromaticContact CE1-CE2 3.7Å; F150-Y407 HydrophobicContact CE1-CE2 3.7Å; F150-Y407 HydrophobicContact CE1-CG 4.24Å; F150-Y407 AromaticContact CE1-CZ 3.45Å; F150-Y407 VanDerWaalsContact CE1-CZ 3.45Å; F150-Y407 HydrophobicContact CZ-CE1 4.42Å; F178-Y407 WeakPolarHBondContact CE1-O 3.48Å; F178-Y407 HydrophobicContact CZ-CD1 4.08Å; M182-Y407 HydrophobicContact CE-CD2 4.3Å; M182-Y407 HydrophobicContact CE-CG 3.92Å; M182-Y407 HydrophobicContact SD-CD1 3.72Å; M182-Y407 HydrophobicContact SD-CD2 4.48Å; M182-Y407 HydrophobicContact SD-CG 3.69Å; T395-Y407 HydrophobicContact CG2-CD1 3.72Å; T395-Y407 HydrophobicContact CG2-CD2 4.24Å; T395-Y407 HydrophobicContact CG2-CE1 3.22Å; T395-Y407 HydrophobicContact CG2-CE2 3.8Å; T395-Y407 HydrophobicContact CG2-CG 4.21Å; T395-Y407 PolarHBondContact N-OH 3.39Å; G396-Y407 PolarHBondContact N-OH 3.31Å; G396-Y407 WeakPolarHBondContact O-CE2 3.5Å; G396-Y407 PolarHBondContact O-OH 3.28Å; R403-Y407 HydrophobicContact CB-CE2 4.46Å; R403-Y407 WeakPolarHBondContact O-CD2 3.35Å; R403-Y407 PolarHBondContact O-N 3.03Å; L404-Y407 HydrophobicContact CD2-CD2 4.5Å; L404-Y407 PolarHBondContact O-N 2.8Å; Y407-Q409 VanDerWaalsContact C-N 3.31Å; Y407-Q409 PolarHBondContact O-N 3.3Å; Y407-L410 HydrophobicContact CD1-CD1 4.42Å; Y407-L410 WeakPolarHBondContact O-CB 3.22Å; Y407-L410 PolarHBondContact O-N 2.88Å; Y407-L411 PolarHBondContact O-N 2.86Å
408N98.9Very high98.8Very high63 Ų6345.6 Ų45.634%0.33724%0.239SC..Hα-helixtrans-67.6-33.5174.7-70.7-27.4000111.7L404 K406 L411 R412L404-N408 WeakPolarHBondContact O-CB 3.17Å; L404-N408 PolarHBondContact O-N 2.68Å; L404-N408 PolarHBondContact O-ND2 2.87Å; L404-N408 VanDerWaalsContact O-ND2 3.12Å; K406-N408 VanDerWaalsContact C-N 3.34Å; K406-N408 PolarHBondContact O-N 3.04Å; N408-L411 PolarHBondContact O-N 3.31Å; N408-R412 WeakPolarHBondContact O-CG 3.41Å; N408-R412 PolarHBondContact O-N 3.3Å; N408-R412 VanDerWaalsContact O-N 3.12Å
409Q98.9Very high98.7Very high38 Ų3851 Ų5118%0.17828%0.277CS..Hα-helixtrans-64.5-41.1171.9-179.1626.400111.5T379 A382 D383 A405 K406 Y407 L411 R412 I413T379-Q409 HydrophobicContact CG2-CB 4.1Å; A382-Q409 HydrophobicContact CB-CB 3.74Å; A382-Q409 HydrophobicContact CB-CG 3.66Å; D383-Q409 WeakPolarHBondContact OD2-CG 3.48Å; D383-Q409 PolarHBondContact OD2-NE2 3.34Å; A405-Q409 WeakPolarHBondContact O-CB 3.23Å; A405-Q409 PolarHBondContact O-N 2.61Å; K406-Q409 WeakPolarHBondContact O-CB 3.23Å; K406-Q409 PolarHBondContact O-N 2.78Å; K406-Q409 VanDerWaalsContact O-N 3.12Å; Y407-Q409 VanDerWaalsContact C-N 3.31Å; Y407-Q409 PolarHBondContact O-N 3.3Å; Q409-L411 VanDerWaalsContact C-N 3.34Å; Q409-L411 PolarHBondContact O-N 2.76Å; Q409-R412 WeakPolarHBondContact O-CB 3.27Å; Q409-R412 PolarHBondContact O-N 2.97Å; Q409-R412 VanDerWaalsContact O-N 3.13Å; Q409-R412 VanDerWaalsContact OE1-NH1 3.13Å; Q409-I413 HydrophobicContact CG-CD1 4.01Å; Q409-I413 HydrophobicContact CG-CG1 4.48Å; Q409-I413 WeakPolarHBondContact O-CG1 3.32Å; Q409-I413 PolarHBondContact O-N 3Å
410L98.9Very high98.6Very high0 Ų057.3 Ų57.30%030%0.301CS..Hα-helixtrans-63.3-36.8174.6-70.4168.1000112.7L145 P146 F178 A382 V385 V386 I393 K406 Y407 R412 I413 E414L145-L410 HydrophobicContact CD2-CD2 4.34Å; P146-L410 HydrophobicContact CG-CD1 4Å; P146-L410 HydrophobicContact CG-CD2 4.06Å; F178-L410 HydrophobicContact CD1-CB 3.81Å; F178-L410 HydrophobicContact CD2-CB 4.44Å; F178-L410 HydrophobicContact CE1-CB 3.25Å; F178-L410 HydrophobicContact CE1-CD1 4.27Å; F178-L410 HydrophobicContact CE1-CG 4.38Å; F178-L410 HydrophobicContact CE2-CB 3.95Å; F178-L410 HydrophobicContact CE2-CD1 3.61Å; F178-L410 HydrophobicContact CE2-CG 4.35Å; F178-L410 HydrophobicContact CG-CB 4.39Å; F178-L410 HydrophobicContact CZ-CB 3.34Å; F178-L410 HydrophobicContact CZ-CD1 3.44Å; F178-L410 VanDerWaalsContact CZ-CD1 3.44Å; F178-L410 HydrophobicContact CZ-CG 4.01Å; A382-L410 HydrophobicContact CB-CD2 4.14Å; A382-L410 HydrophobicContact CB-CG 3.88Å; A382-L410 WeakPolarHBondContact O-CD2 3.26Å; V385-L410 HydrophobicContact CG1-CD2 3.95Å; V386-L410 HydrophobicContact CG2-CD2 3.56Å; I393-L410 HydrophobicContact CD1-CD1 4.35Å; I393-L410 HydrophobicContact CG2-CD1 4.02Å; K406-L410 WeakPolarHBondContact O-CG 3.3Å; K406-L410 PolarHBondContact O-N 3.02Å; Y407-L410 HydrophobicContact CD1-CD1 4.42Å; Y407-L410 WeakPolarHBondContact O-CB 3.22Å; Y407-L410 PolarHBondContact O-N 2.88Å; L410-R412 VanDerWaalsContact C-N 3.33Å; L410-R412 PolarHBondContact O-N 2.91Å; L410-I413 PolarHBondContact O-N 2.85Å; L410-E414 WeakPolarHBondContact O-CB 3.45Å; L410-E414 PolarHBondContact O-N 2.99Å
411L98.9Very high98.6Very high50 Ų5055 Ų5526%0.26230%0.299SS..Hα-helixtrans-61-41.3171.3-70.6170.7000111.9F178 R179 M182 Y407 N408 Q409 E414 E415F178-L411 HydrophobicContact CD1-CD2 3.91Å; F178-L411 HydrophobicContact CD1-CG 4.21Å; F178-L411 HydrophobicContact CE1-CD2 4.15Å; F178-L411 HydrophobicContact CE1-CG 4.03Å; R179-L411 HydrophobicContact CB-CD2 3.85Å; R179-L411 HydrophobicContact CG-CD2 4.17Å; M182-L411 HydrophobicContact CB-CD2 4.4Å; M182-L411 HydrophobicContact CG-CD2 4.1Å; M182-L411 HydrophobicContact CG-CG 4.31Å; Y407-L411 PolarHBondContact O-N 2.86Å; N408-L411 PolarHBondContact O-N 3.31Å; Q409-L411 VanDerWaalsContact C-N 3.34Å; Q409-L411 PolarHBondContact O-N 2.76Å; L411-E414 PolarHBondContact O-N 2.9Å; L411-E415 PolarHBondContact O-N 3.07Å
412R98.9Very high98.5Very high133 Ų13355 Ų5550%0.50229%0.287SS..Hα-helixtrans-67.8-41.9176.9-66.5178.8-157109.63.2112.1N408 Q409 L410 E414 E415 E416N408-R412 WeakPolarHBondContact O-CG 3.41Å; N408-R412 PolarHBondContact O-N 3.3Å; N408-R412 VanDerWaalsContact O-N 3.12Å; Q409-R412 WeakPolarHBondContact O-CB 3.27Å; Q409-R412 PolarHBondContact O-N 2.97Å; Q409-R412 VanDerWaalsContact O-N 3.13Å; Q409-R412 VanDerWaalsContact OE1-NH1 3.13Å; L410-R412 VanDerWaalsContact C-N 3.33Å; L410-R412 PolarHBondContact O-N 2.91Å; R412-E414 VanDerWaalsContact C-N 3.32Å; R412-E414 PolarHBondContact O-N 3.1Å; R412-E415 PolarHBondContact O-N 2.69Å; R412-E416 WeakPolarHBondContact O-CB 3.28Å; R412-E416 PolarHBondContact O-N 3.48Å
413I98.9Very high98.5Very high1 Ų155.7 Ų55.71%0.00529%0.29CS..Hα-helixtrans-62.9-41.9176.4-66.6167.1000110.3Y131 L145 V386 Q409 L410 E416 L417Y131-I413 HydrophobicContact CD1-CB 4.43Å; Y131-I413 HydrophobicContact CD1-CD1 4.06Å; Y131-I413 HydrophobicContact CD1-CG1 3.8Å; Y131-I413 HydrophobicContact CD1-CG2 3.83Å; Y131-I413 HydrophobicContact CE1-CB 4.48Å; Y131-I413 HydrophobicContact CE1-CG1 4.13Å; Y131-I413 HydrophobicContact CE1-CG2 3.88Å; Y131-I413 HydrophobicContact CG-CG2 4.2Å; L145-I413 HydrophobicContact CD2-CG2 4.35Å; V386-I413 HydrophobicContact CG1-CG2 4.01Å; V386-I413 HydrophobicContact CG2-CD1 4.31Å; V386-I413 HydrophobicContact CG2-CG2 4.17Å; Q409-I413 HydrophobicContact CG-CD1 4.01Å; Q409-I413 HydrophobicContact CG-CG1 4.48Å; Q409-I413 WeakPolarHBondContact O-CG1 3.32Å; Q409-I413 PolarHBondContact O-N 3Å; L410-I413 PolarHBondContact O-N 2.85Å; I413-E416 PolarHBondContact O-N 3.44Å; I413-L417 HydrophobicContact CG2-CD1 3.83Å; I413-L417 HydrophobicContact CG2-CG 4.32Å; I413-L417 WeakPolarHBondContact O-CB 3.24Å; I413-L417 VanDerWaalsContact O-CG 3.25Å; I413-L417 WeakPolarHBondContact O-CG 3.3Å; I413-L417 PolarHBondContact O-N 3.25Å
414E98.9Very high98.5Very high24 Ų2456.1 Ų56.111%0.11229%0.294CS..Hα-helixtrans-58.9-46.8174.3-179.3168-113.600112.2L145 N177 F178 R179 L410 L411 R412 L417 G418 A421L145-E414 HydrophobicContact CD1-CB 3.44Å; L145-E414 VanDerWaalsContact CD1-CB 3.44Å; L145-E414 HydrophobicContact CD1-CG 3.47Å; L145-E414 VanDerWaalsContact CD1-CG 3.47Å; L145-E414 WeakPolarHBondContact CD1-OE1 3.39Å; L145-E414 HydrophobicContact CD2-CB 4.22Å; L145-E414 HydrophobicContact CG-CB 4.47Å; N177-E414 WeakPolarHBondContact CB-OE1 3.46Å; F178-E414 WeakPolarHBondContact CA-OE1 3.49Å; F178-E414 VanDerWaalsContact CB-OE1 3.27Å; F178-E414 WeakPolarHBondContact CB-OE1 3.42Å; F178-E414 PolarHBondContact N-OE1 3.44Å; R179-E414 WeakPolarHBondContact CB-OE2 3.5Å; R179-E414 PolarHBondContact N-OE2 2.98Å; L410-E414 WeakPolarHBondContact O-CB 3.45Å; L410-E414 PolarHBondContact O-N 2.99Å; L411-E414 PolarHBondContact O-N 2.9Å; R412-E414 VanDerWaalsContact C-N 3.32Å; R412-E414 PolarHBondContact O-N 3.1Å; E414-L417 PolarHBondContact O-N 3.02Å; E414-G418 PolarHBondContact O-N 2.74Å; E414-G418 VanDerWaalsContact O-N 3.11Å; E414-A421 HydrophobicContact CG-CB 4.24Å
415E98.8Very high98.5Very high164 Ų16454.4 Ų54.477%0.76629%0.287SS*.Hα-helixtrans-61.4-44.7176.9-174.6177.792.600111.9L411 R412 L417 G418L411-E415 PolarHBondContact O-N 3.07Å; R412-E415 PolarHBondContact O-N 2.69Å; E415-L417 VanDerWaalsContact C-N 3.35Å; E415-L417 PolarHBondContact O-N 3.5Å; E415-G418 PolarHBondContact O-N 3.34Å
416E98.8Very high98.5Very high116 Ų11661 Ų6154%0.54231%0.307SS..Hα-helixtrans-63.1-38.6178.6-177.3175-172.200112.5P129 R412 I413 G418P129-E416 WeakPolarHBondContact CG-OE1 3.17Å; R412-E416 WeakPolarHBondContact O-CB 3.28Å; R412-E416 PolarHBondContact O-N 3.48Å; I413-E416 PolarHBondContact O-N 3.44Å; E416-G418 VanDerWaalsContact C-N 3.31Å
417L98.5Very high98.5Very high22 Ų2265.6 Ų65.612%0.11533%0.332CS..Hα-helixtrans-70.9-27.2176.4-71.4170.6000112.5Y131 V143 I413 E414 E415 S419 K420 A421Y131-L417 HydrophobicContact CE2-CD2 3.95Å; V143-L417 HydrophobicContact CG2-CD1 3.81Å; V143-L417 HydrophobicContact CG2-CD2 3.7Å; V143-L417 HydrophobicContact CG2-CG 4.44Å; I413-L417 HydrophobicContact CG2-CD1 3.83Å; I413-L417 HydrophobicContact CG2-CG 4.32Å; I413-L417 WeakPolarHBondContact O-CB 3.24Å; I413-L417 VanDerWaalsContact O-CG 3.25Å; I413-L417 WeakPolarHBondContact O-CG 3.3Å; I413-L417 PolarHBondContact O-N 3.25Å; E414-L417 PolarHBondContact O-N 3.02Å; E415-L417 VanDerWaalsContact C-N 3.35Å; E415-L417 PolarHBondContact O-N 3.5Å; L417-S419 PolarHBondContact O-N 3.39Å; L417-K420 WeakPolarHBondContact O-CB 2.91Å; L417-K420 PolarHBondContact O-N 3.19Å; L417-A421 HydrophobicContact CB-CB 3.89Å
418G98.2Very high98.5Very high43 Ų4366.2 Ų66.244%0.44333%0.334SS..G310 helixtrans52.7-126.617900000112.1E414 E415 E416 K420 A421E414-G418 PolarHBondContact O-N 2.74Å; E414-G418 VanDerWaalsContact O-N 3.11Å; E415-G418 PolarHBondContact O-N 3.34Å; E416-G418 VanDerWaalsContact C-N 3.31Å; G418-K420 PolarHBondContact O-N 2.69Å; G418-K420 VanDerWaalsContact O-N 3.08Å; G418-A421 VanDerWaalsContact O-CB 3.26Å; G418-A421 WeakPolarHBondContact O-CB 3.46Å; G418-A421 PolarHBondContact O-N 3.07Å
419S97.2Very high98.4Very high131 Ų13167.4 Ų67.492%0.91633%0.334SS*.G310 helixtrans-66.2-9.8179.667.40000114.7L417L417-S419 PolarHBondContact O-N 3.39Å
420K97.1Very high98.3Very high164 Ų16469.7 Ų69.771%0.71335%0.347SS*.G310 helixtrans-88.6-9.2175-58.6177.6-179173.70112.5L417 G418 K422L417-K420 WeakPolarHBondContact O-CB 2.91Å; L417-K420 PolarHBondContact O-N 3.19Å; G418-K420 PolarHBondContact O-N 2.69Å; G418-K420 VanDerWaalsContact O-N 3.08Å; K420-K422 PolarHBondContact O-N 2.92Å
421A97.3Very high98.2Very high31 Ų3170.9 Ų70.926%0.25636%0.355SS..  trans-63.4124.3178.500000110.3L145 E414 L417 G418L145-A421 HydrophobicContact CD1-CB 4Å; E414-A421 HydrophobicContact CG-CB 4.24Å; L417-A421 HydrophobicContact CB-CB 3.89Å; G418-A421 VanDerWaalsContact O-CB 3.26Å; G418-A421 WeakPolarHBondContact O-CB 3.46Å; G418-A421 PolarHBondContact O-N 3.07Å
422K98.2Very high97.9Very high90 Ų9072.5 Ų72.539%0.39136%0.364SS..  trans-116.3122.7172.6-63.5-177.4-170.1179.30108.1E142 I144 L145 K420E142-K422 IonicContact OE1-NZ 2.76Å; E142-K422 PolarHBondContact OE1-NZ 3.45Å; E142-K422 IonicContact OE2-NZ 2.7Å; E142-K422 PolarHBondContact OE2-NZ 3.28Å; I144-K422 HydrophobicContact CD1-CB 3.68Å; I144-K422 HydrophobicContact CD1-CD 3.94Å; I144-K422 HydrophobicContact CD1-CG 4.44Å; L145-K422 PolarHBondContact N-O 3.04Å; K420-K422 PolarHBondContact O-N 2.92Å
423F98.7Very high97.1Very high36 Ų3669 Ų6916%0.15836%0.363CS..BIsolated β-bridgetrans-96.5133.1176.2176.9-114000110.2L145 P146 V147 A175 F178 A181 G425L145-F423 HydrophobicContact CB-CD2 4.28Å; P146-F423 WeakPolarHBondContact O-CE2 3.5Å; V147-F423 HydrophobicContact CB-CZ 4.45Å; V147-F423 HydrophobicContact CG2-CE1 4.34Å; V147-F423 HydrophobicContact CG2-CE2 4.17Å; V147-F423 HydrophobicContact CG2-CZ 3.75Å; A175-F423 HydrophobicContact CB-CE1 3.92Å; A175-F423 HydrophobicContact CB-CZ 4.25Å; A175-F423 WeakPolarHBondContact O-CD1 3.18Å; A175-F423 VanDerWaalsContact O-CE1 3.27Å; A175-F423 WeakPolarHBondContact O-CE1 3.48Å; F178-F423 HydrophobicContact CB-CD2 4.15Å; F178-F423 HydrophobicContact CB-CE2 4.39Å; F178-F423 HydrophobicContact CD2-CE2 4.35Å; A181-F423 HydrophobicContact CB-CE2 4.1Å; A181-F423 HydrophobicContact CB-CZ 3.77Å; F423-G425 VanDerWaalsContact C-N 3.34Å; F423-G425 VanDerWaalsContact CE1-CA 3.48Å; F423-G425 PolarHBondContact O-N 2.49Å
424A98.7Very high95.2Very high9 Ų982.1 Ų82.17%0.07442%0.42CS..  trans-64-36.3-17500000113.5I144 L145 V147 G391 R426 N427 P431I144-A424 HydrophobicContact CG2-CB 3.89Å; L145-A424 PolarHBondContact O-N 2.95Å; V147-A424 HydrophobicContact CG2-CB 4.42Å; G391-A424 WeakPolarHBondContact O-CB 3.33Å; A424-R426 PolarHBondContact O-N 3.07Å; A424-N427 WeakPolarHBondContact O-CA 3.48Å; A424-N427 WeakPolarHBondContact O-CB 3.32Å; A424-N427 PolarHBondContact O-N 2.62Å; A424-P431 HydrophobicContact CB-CB 4Å
425G98.6Very high95Very high8 Ų885 Ų858%0.08244%0.435CS..G310 helixtrans50.2-129.5178.900000113V147 V173 F423 N427 F428V147-G425 VanDerWaalsContact CG2-O 3.22Å; V147-G425 WeakPolarHBondContact CG2-O 3.18Å; V173-G425 CarbonylContact O-C 3.53Å; V173-G425 VanDerWaalsContact O-CA 3.26Å; V173-G425 WeakPolarHBondContact O-CA 3.21Å; F423-G425 VanDerWaalsContact C-N 3.34Å; F423-G425 VanDerWaalsContact CE1-CA 3.48Å; F423-G425 PolarHBondContact O-N 2.49Å; G425-N427 PolarHBondContact O-N 3.02Å; G425-N427 VanDerWaalsContact O-N 3.16Å; G425-F428 WeakPolarHBondContact O-CB 3.41Å; G425-F428 PolarHBondContact O-N 3.2Å
426R98.3Very high94.8Very high159 Ų15980.8 Ų80.860%0.642%0.418SS*.G310 helixtrans-65.9-15.4179.5-67.4-175.1176.376.81.4114.1V173 D238 A424 F428V173-R426 HydrophobicContact CB-CG 4.29Å; V173-R426 HydrophobicContact CG2-CG 4.3Å; V173-R426 PolarHBondContact O-N 3.47Å; V173-R426 VanDerWaalsContact O-N 3.16Å; D238-R426 PolarHBondContact O-NH2 3.19Å; D238-R426 VanDerWaalsContact O-NH2 3.12Å; A424-R426 PolarHBondContact O-N 3.07Å; R426-F428 VanDerWaalsContact C-N 3.3Å; R426-F428 PolarHBondContact O-N 2.88Å
427N98.2Very high94.6Very high96 Ų9678.9 Ų78.951%0.51341%0.411SS..G310 helixtrans-91.819.3177.1-60.9-28.4000112.7A424 G425 R429 N430 P431A424-N427 WeakPolarHBondContact O-CA 3.48Å; A424-N427 WeakPolarHBondContact O-CB 3.32Å; A424-N427 PolarHBondContact O-N 2.62Å; G425-N427 PolarHBondContact O-N 3.02Å; G425-N427 VanDerWaalsContact O-N 3.16Å; N427-R429 PolarHBondContact O-N 3.49Å; N427-N430 CarbonylContact O-C 3.53Å; N427-N430 PolarHBondContact O-N 3.45Å; N427-P431 WeakPolarHBondContact O-CA 3.3Å; N427-P431 WeakPolarHBondContact O-CD 3.06Å
428F98.7Very high94.4Very high12 Ų1282.2 Ų82.25%0.05343%0.428CS..THydrogen-bonded Turntrans-52.8-27-176.776.5-84000115V147 L171 V173 V290 G391 Q392 G425 R426V147-F428 HydrophobicContact CB-CB 4.03Å; V147-F428 HydrophobicContact CG2-CB 3.71Å; L171-F428 HydrophobicContact CD2-CE2 4.37Å; V173-F428 HydrophobicContact CG1-CD1 3.88Å; V173-F428 HydrophobicContact CG1-CE1 4.17Å; V290-F428 HydrophobicContact CG2-CE1 4.49Å; V290-F428 HydrophobicContact CG2-CZ 4.08Å; G391-F428 WeakPolarHBondContact O-CB 3.39Å; Q392-F428 HydrophobicContact CB-CB 4.36Å; Q392-F428 HydrophobicContact CB-CD2 4.06Å; Q392-F428 HydrophobicContact CG-CD2 4.27Å; Q392-F428 PolarHBondContact NE2-O 3.29Å; G425-F428 WeakPolarHBondContact O-CB 3.41Å; G425-F428 PolarHBondContact O-N 3.2Å; R426-F428 VanDerWaalsContact C-N 3.3Å; R426-F428 PolarHBondContact O-N 2.88Å
429R98.4Very high94.1Very high89 Ų8984.7 Ų84.734%0.33643%0.428SS..THydrogen-bonded Turntrans-74.1-28177.8-58.3-179.664.4-179.42.8113I313 N338 G366 N427I313-R429 PolarHBondContact O-NH2 3.39Å; N338-R429 PolarHBondContact ND2-NH2 2.64Å; G366-R429 WeakPolarHBondContact CA-O 3.33Å; N427-R429 PolarHBondContact O-N 3.49Å
430N96.8Very high93.9Very high85 Ų8581.6 Ų81.646%0.45540%0.395SS..  trans-155.559.2-168.160.7-30.2000111.2N427 L432 A433N427-N430 CarbonylContact O-C 3.53Å; N427-N430 PolarHBondContact O-N 3.45Å; N430-L432 PolarHBondContact O-N 2.94Å; N430-A433 HydrophobicContact CB-CB 4.06Å; N430-A433 WeakPolarHBondContact ND2-CB 3.26Å; N430-A433 WeakPolarHBondContact O-CB 3.22Å; N430-A433 PolarHBondContact O-N 3.06Å
431P96.3Very high93.7Very high26 Ų2675.7 Ų75.717%0.16937%0.372CS..THydrogen-bonded Turntrans-66.8-16.5-168.428.8-39.4000114.9I144 C389 A424 N427I144-P431 HydrophobicContact CB-CB 4.5Å; I144-P431 HydrophobicContact CG1-CB 4.28Å; I144-P431 HydrophobicContact CG2-CB 3.85Å; I144-P431 HydrophobicContact CG2-CG 4.45Å; C389-P431 WeakPolarHBondContact O-CG 3.42Å; A424-P431 HydrophobicContact CB-CB 4Å; N427-P431 WeakPolarHBondContact O-CA 3.3Å; N427-P431 WeakPolarHBondContact O-CD 3.06Å
432L91.6Very high93.4Very high84 Ų8479.2 Ų79.244%0.4438%0.381SS..THydrogen-bonded Turntrans-98.6-1.8178.2-60.4-179.2000113.1I144 C389 N430 K434I144-L432 HydrophobicContact CD1-CD2 4.18Å; I144-L432 HydrophobicContact CG1-CD2 3.8Å; C389-L432 HydrophobicContact CB-CD1 3.75Å; C389-L432 HydrophobicContact CB-CD2 4.17Å; C389-L432 HydrophobicContact CB-CG 4.08Å; N430-L432 PolarHBondContact O-N 2.94Å; L432-K434 PolarHBondContact O-N 3.19Å
433A83.9Confident93Very high58 Ų5878.3 Ų78.348%0.47938%0.38SS..  trans-64.8135.5174.200000109.7N430N430-A433 HydrophobicContact CB-CB 4.06Å; N430-A433 WeakPolarHBondContact ND2-CB 3.26Å; N430-A433 WeakPolarHBondContact O-CB 3.22Å; N430-A433 PolarHBondContact O-N 3.06Å
434K58.1Low92.5Very high277 Ų27782.1 Ų82.1100%1.20440%0.401SS*.  trans-79.60179.7-69.8-171.8179-179.70112.4L432L432-K434 PolarHBondContact O-N 3.19Å

Retrieved 434 of 434 residues in 149.6 ms (Link to these results)