A0A2K5NX79_CERAT Loading...

Meprin A subunit

AlphaFold DB , UniProt , Accession A0A2K5NX79, Species CERAT (Cercocebus atys, Sooty mangabey), Gene MEP1A, Length 746 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M34.3Very low29.5Very low249 Ų249160.5 Ų160.5100%1.22787%0.871SS**  0109.10-137.9169-93.100105.9
2A28.4Very low29.2Very low102 Ų102162 Ų16284%0.84386%0.864SS**  trans-95148.7-150.100000113.6
3W32.2Very low29.3Very low247 Ų247158.5 Ų158.594%0.93685%0.853SS**  trans-59.8148.2167.1-77.723.5000113.4
4T31.5Very low29.2Very low150 Ų150156.9 Ų156.992%0.9284%0.842SS**  trans-161.2148.4134.135.70000111.8
5R33.6Very low29Very low241 Ų241159.6 Ų159.691%0.90984%0.844SS**  trans-61.3159-176.4-67171.2163.8-171.2-5.6115.6
6S27Very low28.8Very low117 Ų117160.3 Ų160.382%0.81884%0.838SS**  -164.7124.3120.6-104.10000114
7T28.2Very low28.7Very low127 Ų127155.8 Ų155.878%0.77983%0.83SS**  trans-1.1129.5153.746.60000120.7
8C24.8Very low28.5Very low129 Ų129157.3 Ų157.387%0.87283%0.83SS**  trans-115.1123156.1-137.50000108.8
9I29.2Very low28.5Very low151 Ų151156.6 Ų156.677%0.77483%0.826SS**  trans-80124.6179.4-67.9168000108.1
10L27.8Very low28.4Very low146 Ų146152.7 Ų152.776%0.76482%0.817SS**  trans-76.5115.4166.3-94.6111.3000109F12L10-F12 HydrophobicContact CD2-CD2 4.14Å; L10-F12 HydrophobicContact CD2-CE2 3.91Å
11S27.1Very low28.2Very low106 Ų106149.2 Ų149.274%0.74181%0.809SS**  trans-90.8106.9159-76.20000108.5T13S11-T13 PolarHBondContact O-N 2.72Å
12F26.8Very low27.9Very low179 Ų179142 Ų14279%0.78578%0.779SS**  trans-78.7103.4163.5-104.1-93.7000108.1L10L10-F12 HydrophobicContact CD2-CD2 4.14Å; L10-F12 HydrophobicContact CD2-CE2 3.91Å
13T30.1Very low27.9Very low117 Ų117141.4 Ų141.472%0.71877%0.769SS**  trans-90.5102.5161.641.80000108.2S11 F15S11-T13 PolarHBondContact O-N 2.72Å; T13-F15 PolarHBondContact O-N 3.34Å
14L27.2Very low28Very low135 Ų135133.9 Ų133.971%0.70775%0.746SS**  trans-63.3109.8166.5-92.4132.4000108.9F16L14-F16 HydrophobicContact CB-CD2 4.46Å; L14-F16 HydrophobicContact CB-CE2 4.44Å; L14-F16 PolarHBondContact O-N 3.33Å
15F27.3Very low28.5Very low198 Ų198132.3 Ų132.387%0.86873%0.726SS**  trans-73.8105.3160.3-96.8-93.3000107.7T13 A17T13-F15 PolarHBondContact O-N 3.34Å; F15-A17 PolarHBondContact O-N 3.45Å
16F25.7Very low28.7Very low171 Ų171126.9 Ų126.975%0.7571%0.707SS**  trans-74.4105161.5-87.4-90.7000107.5L14 H18L14-F16 HydrophobicContact CB-CD2 4.46Å; L14-F16 HydrophobicContact CB-CE2 4.44Å; L14-F16 PolarHBondContact O-N 3.33Å; F16-H18 PolarHBondContact O-N 3.26Å
17A26.6Very low29.4Very low84 Ų84123.4 Ų123.469%0.69468%0.679SS**  trans-71110.8162.300000107.5F15 I19F15-A17 PolarHBondContact O-N 3.45Å; A17-I19 VanDerWaalsContact C-N 3.31Å; A17-I19 PolarHBondContact O-N 3.47Å
18H24.9Very low29.7Very low182 Ų182121.5 Ų121.584%0.84367%0.668SS**  trans-73.691.5165.7-85.5-60.3000108F16 A20F16-H18 PolarHBondContact O-N 3.26Å; H18-A20 PolarHBondContact O-N 3.1Å
19I28.2Very low30.2Very low144 Ų144123.1 Ų123.174%0.73866%0.66SS**  trans-71.6118.3161.8-60.3171.6000105.6A17 A21A17-I19 VanDerWaalsContact C-N 3.31Å; A17-I19 PolarHBondContact O-N 3.47Å; I19-A21 PolarHBondContact O-N 3.32Å
20A26.3Very low30.5Very low79 Ų79121.7 Ų121.765%0.65365%0.65SS**  trans-68.483.8165.500000107.6H18 V22H18-A20 PolarHBondContact O-N 3.1Å; A20-V22 PolarHBondContact O-N 2.79Å
21A25.4Very low30.8Very low79 Ų79121.7 Ų121.765%0.65365%0.651SS**  trans-65115.6171.200000108I19 S23I19-A21 PolarHBondContact O-N 3.32Å; A21-S23 PolarHBondContact O-N 2.99Å; A21-S23 VanDerWaalsContact O-N 3.12Å
22V27.8Very low31.6Very low99 Ų99118.5 Ų118.560%0.663%0.627SS**  trans-51.7121.3154.4176.60000105.8A20 I24A20-V22 PolarHBondContact O-N 2.79Å; V22-I24 VanDerWaalsContact C-N 3.31Å; V22-I24 PolarHBondContact O-N 2.93Å
23S28.5Very low33Very low88 Ų88115.7 Ų115.762%0.61562%0.617SS**  trans-68.889.5-172.5-165.80000109.5A21 K25A21-S23 PolarHBondContact O-N 2.99Å; A21-S23 VanDerWaalsContact O-N 3.12Å; S23-K25 VanDerWaalsContact C-N 3.32Å; S23-K25 PolarHBondContact O-N 3.38Å
24I34Very low34.4Very low89 Ų89111.3 Ų111.346%0.45659%0.589SS.*  trans-66.897.3163.1-62.3-179.2000105.7V22 Y26 V444 L454V22-I24 VanDerWaalsContact C-N 3.31Å; V22-I24 PolarHBondContact O-N 2.93Å; I24-Y26 PolarHBondContact O-N 3.47Å; I24-Y26 VanDerWaalsContact O-N 3.13Å; I24-V444 HydrophobicContact CD1-CG2 4.23Å; I24-L454 HydrophobicContact CG2-CD2 3.57Å
25K42.9Very low36Very low117 Ų117105.8 Ų105.851%0.50956%0.563SS.*  trans-8099.5-179.4-73.9-174.6-178.1176.50109.3S23 L27 D556S23-K25 VanDerWaalsContact C-N 3.32Å; S23-K25 PolarHBondContact O-N 3.38Å; K25-L27 PolarHBondContact O-N 2.93Å; K25-D556 HydrophobicContact CD-CB 4.17Å
26Y37.8Very low38Very low128 Ų12899.7 Ų99.750%0.50254%0.539SS..  trans-66.3111.9166.2-179.1-94.8000109.2I24 P28 D452I24-Y26 PolarHBondContact O-N 3.47Å; I24-Y26 VanDerWaalsContact O-N 3.13Å; Y26-P28 HydrophobicContact CE1-CB 4.33Å; Y26-D452 HydrophobicContact CE2-CB 4.14Å; Y26-D452 PolarHBondContact OH-OD1 3.17Å; Y26-D452 PolarHBondContact OH-OD2 2.74Å
27L40.6Very low40.2Very low44 Ų4494 Ų9423%0.2351%0.514CS..BIsolated β-bridgetrans-96.5115.4171-71174.1000108.6K25K25-L27 PolarHBondContact O-N 2.93Å
28P33.9Very low42Very low86 Ų8693 Ų9356%0.55851%0.511SS*.  trans-64.5148.7175.326.6-31.7000110.3Y26 E30Y26-P28 HydrophobicContact CE1-CB 4.33Å; P28-E30 PolarHBondContact O-N 3.33Å
29K35.3Very low44.4Very low163 Ų16392.9 Ų92.971%0.70951%0.511SS*.  trans-30.191.5176.6-163.1177.6-172.8177.90114.8
30E36.4Very low46.9Very low121 Ų12188.7 Ų88.757%0.56549%0.488SS*.  trans-88.3140.7160.3-76.6-174.6158.200108.8P28 V32P28-E30 PolarHBondContact O-N 3.33Å; E30-V32 HydrophobicContact CB-CG2 3.93Å; E30-V32 PolarHBondContact O-N 3.41Å
31N33.8Very low49.9Very low146 Ų14690.1 Ų90.178%0.78148%0.48SS*.  trans-72.967.4171.6-72.7-29.2000109.4
32V44.7Very low53.1Low39 Ų3986.5 Ų86.524%0.23645%0.45CS..  trans-88.9120.6167.7-170.40000106.6E30 D34E30-V32 HydrophobicContact CB-CG2 3.93Å; E30-V32 PolarHBondContact O-N 3.41Å; V32-D34 WeakPolarHBondContact CG1-OD1 3.42Å
33H54.8Low56.3Low121 Ų12181.9 Ų81.956%0.5642%0.422SS*.  trans-92.6121.1179.5-66.7-79.3000108.7V537 I563H33-V537 HydrophobicContact CB-CB 4.03Å; H33-V537 HydrophobicContact CB-CG1 3.72Å; H33-V537 HydrophobicContact CB-CG2 3.1Å; H33-I563 VanDerWaalsContact O-CG2 3.29Å; H33-I563 WeakPolarHBondContact O-CG2 3.41Å
34D59.8Low59.5Low25 Ų2578 Ų7813%0.13439%0.394CS..  trans-115.2162.1-169.1-63.7-22.8000111.2V32 Y472 R476 I563 D564V32-D34 WeakPolarHBondContact CG1-OD1 3.42Å; D34-Y472 PolarHBondContact OD2-OH 2.75Å; D34-R476 IonicContact OD2-CZ 3.87Å; D34-R476 VanDerWaalsContact OD2-CZ 3.23Å; D34-R476 IonicContact OD2-NE 3.69Å; D34-R476 PolarHBondContact OD2-NE 3.49Å; D34-R476 IonicContact OD2-NH2 2.62Å; D34-R476 PolarHBondContact OD2-NH2 3.27Å; D34-I563 HydrophobicContact CB-CG2 4.46Å; D34-D564 HydrophobicContact CB-CB 4.19Å; D34-D564 WeakPolarHBondContact CB-O 3.45Å
35A60.8Low62.3Low19 Ų1977.8 Ų77.816%0.15739%0.391CS..EExtended strand (participates in β ladder)trans-108.8139.4178.700000111.1R483 I543 D564 F565 G566A35-R483 PolarHBondContact O-NH2 3.21Å; A35-R483 VanDerWaalsContact O-NH2 3.16Å; A35-I543 HydrophobicContact CB-CD1 3.81Å; A35-D564 PolarHBondContact N-O 2.9Å; A35-F565 HydrophobicContact CB-CD2 3.54Å; A35-F565 HydrophobicContact CB-CE2 4Å; A35-F565 WeakPolarHBondContact O-CA 3.39Å; A35-G566 PolarHBondContact O-N 2.92Å
36D70.7Confident64.8Low69 Ų6973 Ų7337%0.36937%0.372SS..EExtended strand (participates in β ladder)trans-124.8141.4-170.4-65.32.4000110.4R476 R483 G566 S568D36-R476 VanDerWaalsContact CG-NH1 3.34Å; D36-R476 IonicContact OD1-CZ 2.93Å; D36-R476 IonicContact OD1-NH1 3.66Å; D36-R476 PolarHBondContact OD1-NH1 3.45Å; D36-R476 IonicContact OD1-NH2 3.97Å; D36-R476 PolarHBondContact OD1-NH2 2.9Å; D36-R476 IonicContact OD2-NH1 3.49Å; D36-R476 PolarHBondContact OD2-NH1 2.95Å; D36-R476 VanDerWaalsContact OD2-NH1 3.09Å; D36-R483 IonicContact OD1-CZ 3.11Å; D36-R483 IonicContact OD1-NE 3.46Å; D36-R483 IonicContact OD1-NH1 2.99Å; D36-R483 PolarHBondContact OD1-NH1 2.89Å; D36-R483 IonicContact OD1-NH2 2.8Å; D36-R483 PolarHBondContact OD1-NH2 3.38Å; D36-R483 IonicContact OD2-CZ 2.83Å; D36-R483 IonicContact OD2-NH1 2.7Å; D36-R483 PolarHBondContact OD2-NH1 3.44Å; D36-G566 WeakPolarHBondContact CA-O 3.11Å; D36-S568 PolarHBondContact OD2-OG 3.13Å
37F71.7Confident67.6Low53 Ų5367 Ų6723%0.23235%0.348CS..EExtended strand (participates in β ladder)trans-68.9146.3157.2-70.8-74.8000109.7F527 F565 G566 W567F37-F527 HydrophobicContact CE1-CB 4.41Å; F37-F527 HydrophobicContact CE2-CB 3.86Å; F37-F527 AromaticContact CE2-CD1 3.84Å; F37-F527 HydrophobicContact CE2-CD1 3.84Å; F37-F527 AromaticContact CE2-CG 3.9Å; F37-F527 HydrophobicContact CE2-CG 3.9Å; F37-F527 HydrophobicContact CZ-CB 3.39Å; F37-F527 HydrophobicContact CZ-CD1 4.21Å; F37-F527 HydrophobicContact CZ-CD2 4.4Å; F37-F527 AromaticContact CZ-CG 3.78Å; F37-F527 HydrophobicContact CZ-CG 3.78Å; F37-F565 HydrophobicContact CD1-CZ 4.48Å; F37-F565 HydrophobicContact CD2-CE1 4.18Å; F37-F565 HydrophobicContact CD2-CZ 4.39Å; F37-F565 AromaticContact CE1-CE1 3.96Å; F37-F565 HydrophobicContact CE1-CE1 3.96Å; F37-F565 AromaticContact CE1-CZ 3.85Å; F37-F565 HydrophobicContact CE1-CZ 3.85Å; F37-F565 AromaticContact CE2-CD1 3.75Å; F37-F565 HydrophobicContact CE2-CD1 3.75Å; F37-F565 AromaticContact CE2-CE1 3.21Å; F37-F565 HydrophobicContact CE2-CE1 3.21Å; F37-F565 AromaticContact CE2-CZ 3.75Å; F37-F565 HydrophobicContact CE2-CZ 3.75Å; F37-F565 HydrophobicContact CZ-CD1 4.07Å; F37-F565 AromaticContact CZ-CE1 3.09Å; F37-F565 HydrophobicContact CZ-CE1 3.09Å; F37-F565 AromaticContact CZ-CZ 3.46Å; F37-F565 HydrophobicContact CZ-CZ 3.46Å; F37-F565 VanDerWaalsContact CZ-CZ 3.46Å; F37-G566 PolarHBondContact N-O 3.18Å; F37-W567 HydrophobicContact CB-CG 4.26Å; F37-W567 AromaticContact CD2-CD1 3.96Å; F37-W567 AromaticContact CD2-CD2 3.83Å; F37-W567 HydrophobicContact CD2-CD2 3.83Å; F37-W567 AromaticContact CD2-CE2 3.4Å; F37-W567 HydrophobicContact CD2-CG 4.16Å; F37-W567 AromaticContact CD2-CZ2 3.8Å; F37-W567 HydrophobicContact CD2-CZ2 3.8Å; F37-W567 AromaticContact CD2-NE1 3.47Å; F37-W567 HydrophobicContact CE2-CD2 4.42Å; F37-W567 AromaticContact CE2-CE2 3.81Å; F37-W567 HydrophobicContact CE2-CH2 4.23Å; F37-W567 AromaticContact CE2-CZ2 3.69Å; F37-W567 HydrophobicContact CE2-CZ2 3.69Å; F37-W567 AromaticContact CG-NE1 3.6Å; F37-W567 HydrophobicContact CZ-CZ2 4.4Å
38G64.5Low70.2Confident62 Ų6267.4 Ų67.464%0.63935%0.35SS*.PPolyproline II helixtrans-61.6172171.200000112.1Q40G38-Q40 PolarHBondContact O-N 2.9Å
39E73.9Confident73Confident180 Ų18067.1 Ų67.184%0.84136%0.355SS*.PPolyproline II helixtrans-57.3133.7173-174171.4-159.300110.7K41E39-K41 PolarHBondContact O-N 3.36Å
40Q81.6Confident75.8Confident55 Ų5561.1 Ų61.126%0.25734%0.336SS..  trans-70.8113.3174-179.1-178.21.800108.3G38 Y149G38-Q40 PolarHBondContact O-N 2.9Å; Q40-Y149 HydrophobicContact CB-CE1 4.32Å; Q40-Y149 HydrophobicContact CG-CD1 4.19Å; Q40-Y149 HydrophobicContact CG-CD2 4.18Å; Q40-Y149 HydrophobicContact CG-CE1 3.92Å; Q40-Y149 HydrophobicContact CG-CE2 3.91Å; Q40-Y149 HydrophobicContact CG-CG 4.32Å
41K88.4Confident78.6Confident109 Ų10958.3 Ų58.347%0.47434%0.339SS..  trans-83.6148.9175.3-64.5-173.3177.3-172.40110.6E39 E45 I46E39-K41 PolarHBondContact O-N 3.36Å; K41-E45 HydrophobicContact CB-CB 4.19Å; K41-I46 HydrophobicContact CB-CD1 4.41Å; K41-I46 HydrophobicContact CB-CG1 3.88Å
42D92.9Very high81.4Confident4 Ų452.9 Ų52.92%0.02131%0.31CS..  trans-75161.5172.2-169.230.2000112.1S44 E45 I46 R242D42-S44 VanDerWaalsContact C-N 3.27Å; D42-S44 PolarHBondContact O-N 3.49Å; D42-S44 PolarHBondContact OD2-OG 3.3Å; D42-E45 PolarHBondContact N-OE1 3.02Å; D42-E45 WeakPolarHBondContact O-CB 3.4Å; D42-E45 PolarHBondContact O-N 2.97Å; D42-I46 WeakPolarHBondContact O-CG1 3.4Å; D42-I46 PolarHBondContact O-N 3.41Å; D42-R242 VanDerWaalsContact CG-NH2 3.29Å; D42-R242 IonicContact OD1-CZ 3.52Å; D42-R242 IonicContact OD1-NE 3.09Å; D42-R242 PolarHBondContact OD1-NE 3.01Å; D42-R242 IonicContact OD1-NH2 2.72Å; D42-R242 PolarHBondContact OD1-NH2 3.14Å; D42-R242 IonicContact OD2-NH2 2.79Å; D42-R242 PolarHBondContact OD2-NH2 3.12Å; D42-R242 VanDerWaalsContact OD2-NH2 3.15Å
43I96.1Very high83.7Confident2 Ų256.4 Ų56.41%0.0133%0.328CS..Hα-helixtrans-53.4-46.1-179.7-62.5168000110.9E45 I46 N47 D58 C128 I152 H155I43-E45 VanDerWaalsContact C-N 3.3Å; I43-E45 PolarHBondContact O-N 3.44Å; I43-I46 PolarHBondContact O-N 2.92Å; I43-N47 WeakPolarHBondContact O-CB 3.22Å; I43-N47 PolarHBondContact O-N 3.3Å; I43-D58 HydrophobicContact CG2-CB 3.63Å; I43-D58 VanDerWaalsContact CG2-OD2 3.31Å; I43-D58 WeakPolarHBondContact CG2-OD2 3.24Å; I43-C128 HydrophobicContact CG1-CB 4.37Å; I43-C128 HydrophobicContact CG2-CB 4.01Å; I43-I152 HydrophobicContact CD1-CB 4.44Å; I43-I152 HydrophobicContact CD1-CG1 4.3Å; I43-I152 HydrophobicContact CD1-CG2 3.97Å; I43-I152 HydrophobicContact CG1-CB 4.4Å; I43-I152 HydrophobicContact CG1-CD1 4.2Å; I43-I152 HydrophobicContact CG1-CG1 3.97Å; I43-I152 HydrophobicContact CG1-CG2 3.81Å; I43-H155 HydrophobicContact CD1-CB 4.1Å; I43-H155 VanDerWaalsContact CD1-CD2 3.41Å; I43-H155 WeakPolarHBondContact CD1-CD2 3.44Å
44S94.4Very high85.5Confident6 Ų651.8 Ų51.84%0.04231%0.307CS..Hα-helixtrans-57.5-39.8178.7570000113D42 L48 S218D42-S44 VanDerWaalsContact C-N 3.27Å; D42-S44 PolarHBondContact O-N 3.49Å; D42-S44 PolarHBondContact OD2-OG 3.3Å; S44-L48 WeakPolarHBondContact O-CB 3.3Å; S44-L48 PolarHBondContact O-N 3.31Å; S44-S218 PolarHBondContact OG-OG 3.28Å
45E94Very high87.2Confident84 Ų8451.7 Ų51.739%0.39331%0.305SS..Hα-helixtrans-72.6-40.4176.8-67.1177.4-106.900112.6K41 D42 I43 A49K41-E45 HydrophobicContact CB-CB 4.19Å; D42-E45 PolarHBondContact N-OE1 3.02Å; D42-E45 WeakPolarHBondContact O-CB 3.4Å; D42-E45 PolarHBondContact O-N 2.97Å; I43-E45 VanDerWaalsContact C-N 3.3Å; I43-E45 PolarHBondContact O-N 3.44Å; E45-A49 VanDerWaalsContact O-CB 3.23Å; E45-A49 WeakPolarHBondContact O-CB 3.46Å; E45-A49 PolarHBondContact O-N 3.44Å
46I94.9Very high88.8Confident18 Ų1850.8 Ų50.89%0.09230%0.298CS..Hα-helixtrans-62-48178.7-65.5166.9000109.7K41 D42 I43 A49 A50 G146 I152K41-I46 HydrophobicContact CB-CD1 4.41Å; K41-I46 HydrophobicContact CB-CG1 3.88Å; D42-I46 WeakPolarHBondContact O-CG1 3.4Å; D42-I46 PolarHBondContact O-N 3.41Å; I43-I46 PolarHBondContact O-N 2.92Å; I46-A49 PolarHBondContact O-N 2.95Å; I46-A50 WeakPolarHBondContact O-CB 3.48Å; I46-A50 PolarHBondContact O-N 3.49Å; I46-G146 VanDerWaalsContact CD1-O 3.3Å; I46-G146 WeakPolarHBondContact CD1-O 3.47Å; I46-I152 HydrophobicContact CD1-CD1 4.32Å
47N97Very high90Very high1 Ų147.6 Ų47.61%0.00528%0.281CS..Hα-helixtrans-70.1-40.4-177.6-69.5-6000112.3I43 A50 G51 L52 G57 D58 G127 C128I43-N47 WeakPolarHBondContact O-CB 3.22Å; I43-N47 PolarHBondContact O-N 3.3Å; N47-A50 CarbonylContact O-C 3.5Å; N47-A50 WeakPolarHBondContact O-CB 3.24Å; N47-A50 PolarHBondContact O-N 3.04Å; N47-G51 PolarHBondContact O-N 2.89Å; N47-L52 HydrophobicContact CB-CB 4.33Å; N47-L52 HydrophobicContact CB-CD1 4.29Å; N47-L52 PolarHBondContact O-N 2.76Å; N47-G57 WeakPolarHBondContact CB-O 3.35Å; N47-G57 PolarHBondContact ND2-O 3.12Å; N47-D58 WeakPolarHBondContact ND2-CB 3.49Å; N47-G127 WeakPolarHBondContact OD1-CA 3.29Å; N47-C128 PolarHBondContact ND2-O 3.4Å; N47-C128 PolarHBondContact OD1-N 3.39Å; N47-C128 PolarHBondContact OD1-O 3.14Å
48L94.2Very high91.2Very high53 Ų5345.3 Ų45.328%0.27727%0.271SS..Hα-helixtrans-61.2-45.1173.8-179.865000111.3S44 A50 G51 L184 Y187S44-L48 WeakPolarHBondContact O-CB 3.3Å; S44-L48 PolarHBondContact O-N 3.31Å; L48-A50 PolarHBondContact O-N 2.94Å; L48-G51 PolarHBondContact O-N 3.45Å; L48-L184 HydrophobicContact CD1-CD1 4.28Å; L48-L184 HydrophobicContact CD2-CD1 3.46Å; L48-L184 VanDerWaalsContact CD2-CD1 3.46Å; L48-Y187 HydrophobicContact CD1-CE1 3.81Å; L48-Y187 HydrophobicContact CD1-CE2 3.88Å; L48-Y187 VanDerWaalsContact CD1-OH 3.29Å; L48-Y187 WeakPolarHBondContact CD1-OH 3.36Å
49A93.8Very high92.7Very high80 Ų8042.4 Ų42.466%0.66124%0.241SC*.Hα-helixtrans-65.3-28.6176.800000112.6E45 I46 G51E45-A49 VanDerWaalsContact O-CB 3.23Å; E45-A49 WeakPolarHBondContact O-CB 3.46Å; E45-A49 PolarHBondContact O-N 3.44Å; I46-A49 PolarHBondContact O-N 2.95Å; A49-G51 PolarHBondContact O-N 3.28Å
50A94.1Very high93.6Very high37 Ų3735.3 Ų35.331%0.30621%0.209SC..THydrogen-bonded Turntrans-77.3-5.3172.400000113.7I46 N47 L48 L52 N126I46-A50 WeakPolarHBondContact O-CB 3.48Å; I46-A50 PolarHBondContact O-N 3.49Å; N47-A50 CarbonylContact O-C 3.5Å; N47-A50 WeakPolarHBondContact O-CB 3.24Å; N47-A50 PolarHBondContact O-N 3.04Å; L48-A50 PolarHBondContact O-N 2.94Å; A50-L52 VanDerWaalsContact C-N 3.31Å; A50-L52 HydrophobicContact CB-CD1 4.17Å; A50-L52 HydrophobicContact CB-CG 3.97Å; A50-N126 HydrophobicContact CB-CB 4.19Å
51G93.9Very high93.9Very high61 Ų6136.2 Ų36.263%0.62922%0.215SC*.THydrogen-bonded Turntrans70.826.1-178.500000113.5N47 L48 A49N47-G51 PolarHBondContact O-N 2.89Å; L48-G51 PolarHBondContact O-N 3.45Å; A49-G51 PolarHBondContact O-N 3.28Å
52L93.3Very high93Very high33 Ų3335.9 Ų35.917%0.17322%0.215CC..  trans-85.5135.4177.6-58.4177.1000110.1N47 A50 L54 N126N47-L52 HydrophobicContact CB-CB 4.33Å; N47-L52 HydrophobicContact CB-CD1 4.29Å; N47-L52 PolarHBondContact O-N 2.76Å; A50-L52 VanDerWaalsContact C-N 3.31Å; A50-L52 HydrophobicContact CB-CD1 4.17Å; A50-L52 HydrophobicContact CB-CG 3.97Å; L52-L54 HydrophobicContact CB-CD1 4.29Å; L52-L54 HydrophobicContact CB-CG 4.18Å; L52-L54 HydrophobicContact CD1-CD1 4.16Å; L52-N126 WeakPolarHBondContact CD1-O 3.31Å
53D92.3Very high91.2Very high113 Ų11343.3 Ų43.360%0.60426%0.255SS*.  trans-118.971.1174.9-168.227000108.1H189D53-H189 IonicContact OD1-CE1 2.75Å; D53-H189 PolarHBondContact OD1-CE1 2.87Å; D53-H189 IonicContact OD1-NE2 2.96Å
54L94.1Very high89.4Confident24 Ų2446.4 Ų46.413%0.12628%0.277CS..  trans-93.4157.5-179.1-63.2172.2000110.1L52 Q56 G57 L60 W129L52-L54 HydrophobicContact CB-CD1 4.29Å; L52-L54 HydrophobicContact CB-CG 4.18Å; L52-L54 HydrophobicContact CD1-CD1 4.16Å; L54-Q56 PolarHBondContact O-N 3.02Å; L54-G57 PolarHBondContact O-N 3.11Å; L54-L60 HydrophobicContact CD2-CD1 3.99Å; L54-W129 HydrophobicContact CD1-CB 3.51Å; L54-W129 HydrophobicContact CD1-CD2 4.5Å; L54-W129 HydrophobicContact CD1-CG 3.63Å
55F94.3Very high87.7Confident22 Ų2252.7 Ų52.710%0.09630%0.299CS..BIsolated β-bridgetrans-60.7125.2175.9178.9-109000109.2G57 I59 L61 Y164 Y194F55-G57 PolarHBondContact O-N 2.9Å; F55-G57 VanDerWaalsContact O-N 3.09Å; F55-I59 HydrophobicContact CB-CB 4.23Å; F55-I59 HydrophobicContact CB-CG2 4.49Å; F55-I59 WeakPolarHBondContact CB-O 3.34Å; F55-I59 HydrophobicContact CD1-CB 3.91Å; F55-I59 HydrophobicContact CD1-CD1 4.02Å; F55-I59 HydrophobicContact CD1-CG2 3.91Å; F55-I59 HydrophobicContact CE1-CD1 4.34Å; F55-I59 PolarHBondContact N-O 3.2Å; F55-I59 WeakPolarHBondContact O-CA 3.48Å; F55-I59 VanDerWaalsContact O-CB 3.24Å; F55-I59 WeakPolarHBondContact O-CB 3.48Å; F55-I59 PolarHBondContact O-N 3.5Å; F55-L61 HydrophobicContact CB-CD1 3.58Å; F55-L61 HydrophobicContact CB-CD2 4.44Å; F55-L61 HydrophobicContact CB-CG 3.69Å; F55-L61 HydrophobicContact CD1-CD1 4.15Å; F55-L61 HydrophobicContact CD1-CD2 4.1Å; F55-L61 HydrophobicContact CD1-CG 4.25Å; F55-L61 HydrophobicContact CD2-CD1 3.78Å; F55-L61 HydrophobicContact CE2-CD1 4.47Å; F55-L61 HydrophobicContact CG-CD1 3.58Å; F55-L61 HydrophobicContact CG-CD2 4.33Å; F55-L61 HydrophobicContact CG-CG 3.98Å; F55-Y164 HydrophobicContact CD1-CE1 4.26Å; F55-Y164 HydrophobicContact CE1-CD1 4.02Å; F55-Y164 AromaticContact CE1-CE1 3.65Å; F55-Y164 HydrophobicContact CE1-CE1 3.65Å; F55-Y194 HydrophobicContact CE2-CE1 4.02Å; F55-Y194 AromaticContact CE2-CZ 3.65Å; F55-Y194 WeakPolarHBondContact CE2-OH 3.45Å; F55-Y194 AromaticContact CZ-CE1 3.71Å; F55-Y194 HydrophobicContact CZ-CE1 3.71Å; F55-Y194 AromaticContact CZ-CE2 3.9Å; F55-Y194 HydrophobicContact CZ-CE2 3.9Å; F55-Y194 AromaticContact CZ-CZ 3.31Å; F55-Y194 WeakPolarHBondContact CZ-OH 3.36Å
56Q94.3Very high85.8Confident0 Ų050.4 Ų50.40%029%0.29CS..THydrogen-bonded Turntrans51.633.8-174.1-46.1-158.2-65.900112.9L54 D58 I59 H165 S168 N190 Y214L54-Q56 PolarHBondContact O-N 3.02Å; Q56-D58 VanDerWaalsContact C-N 3.26Å; Q56-D58 PolarHBondContact O-N 3.03Å; Q56-D58 VanDerWaalsContact O-N 3.11Å; Q56-I59 HydrophobicContact CB-CD1 4.29Å; Q56-I59 HydrophobicContact CG-CD1 4.5Å; Q56-H165 WeakPolarHBondContact CB-ND1 3.47Å; Q56-H165 PolarHBondContact O-CE1 2.79Å; Q56-H165 VanDerWaalsContact O-CE1 3.28Å; Q56-H165 PolarHBondContact OE1-ND1 3.14Å; Q56-H165 VanDerWaalsContact OE1-ND1 3.15Å; Q56-S168 VanDerWaalsContact NE2-CB 3.34Å; Q56-S168 PolarHBondContact NE2-OG 3.08Å; Q56-N190 WeakPolarHBondContact CA-OD1 3.16Å; Q56-N190 PolarHBondContact N-OD1 3.34Å; Q56-Y214 WeakPolarHBondContact CA-OH 3.45Å; Q56-Y214 PolarHBondContact O-OH 3.23Å
57G95.7Very high83.9Confident3 Ų349.9 Ų49.93%0.03129%0.289CS..THydrogen-bonded Turntrans82.7-31.6173.400000116.6N47 L54 F55 N190N47-G57 WeakPolarHBondContact CB-O 3.35Å; N47-G57 PolarHBondContact ND2-O 3.12Å; L54-G57 PolarHBondContact O-N 3.11Å; F55-G57 PolarHBondContact O-N 2.9Å; F55-G57 VanDerWaalsContact O-N 3.09Å; G57-N190 PolarHBondContact N-OD1 2.84Å
58D97.3Very high82.1Confident4 Ų450.2 Ų50.22%0.02129%0.291CS..THydrogen-bonded Turntrans-145.85.9-171.955.513.5000114.6I43 N47 Q56 C128 W129 S130 H155 H159 H165I43-D58 HydrophobicContact CG2-CB 3.63Å; I43-D58 VanDerWaalsContact CG2-OD2 3.31Å; I43-D58 WeakPolarHBondContact CG2-OD2 3.24Å; N47-D58 WeakPolarHBondContact ND2-CB 3.49Å; Q56-D58 VanDerWaalsContact C-N 3.26Å; Q56-D58 PolarHBondContact O-N 3.03Å; Q56-D58 VanDerWaalsContact O-N 3.11Å; D58-C128 WeakPolarHBondContact CB-O 3.44Å; D58-W129 HydrophobicContact CB-CB 4.31Å; D58-W129 WeakPolarHBondContact O-CA 3.23Å; D58-W129 WeakPolarHBondContact O-CB 3.28Å; D58-S130 PolarHBondContact O-N 2.73Å; D58-S130 VanDerWaalsContact O-N 3.11Å; D58-H155 IonicContact OD2-CD2 3.84Å; D58-H155 IonicContact OD2-NE2 2.88Å; D58-H155 PolarHBondContact OD2-NE2 2.81Å; D58-H159 IonicContact OD1-NE2 2.88Å; D58-H159 PolarHBondContact OD1-NE2 3.09Å; D58-H159 IonicContact OD2-NE2 3.68Å; D58-H165 IonicContact OD1-CE1 3.76Å; D58-H165 PolarHBondContact OD1-CE1 3.23Å; D58-H165 IonicContact OD1-NE2 3.32Å; D58-H165 IonicContact OD2-CE1 3.13Å; D58-H165 IonicContact OD2-NE2 3.75Å; D58-H165 PolarHBondContact OD2-NE2 3Å
59I96.1Very high80.7Confident1 Ų155 Ų551%0.00531%0.305CS..BIsolated β-bridgetrans-98.8120.8176-60.7169000109.9F55 Q56 L61 S130 V132 Y164F55-I59 HydrophobicContact CB-CB 4.23Å; F55-I59 HydrophobicContact CB-CG2 4.49Å; F55-I59 WeakPolarHBondContact CB-O 3.34Å; F55-I59 HydrophobicContact CD1-CB 3.91Å; F55-I59 HydrophobicContact CD1-CD1 4.02Å; F55-I59 HydrophobicContact CD1-CG2 3.91Å; F55-I59 HydrophobicContact CE1-CD1 4.34Å; F55-I59 PolarHBondContact N-O 3.2Å; F55-I59 WeakPolarHBondContact O-CA 3.48Å; F55-I59 VanDerWaalsContact O-CB 3.24Å; F55-I59 WeakPolarHBondContact O-CB 3.48Å; F55-I59 PolarHBondContact O-N 3.5Å; Q56-I59 HydrophobicContact CB-CD1 4.29Å; Q56-I59 HydrophobicContact CG-CD1 4.5Å; I59-L61 HydrophobicContact CG2-CD2 4.06Å; I59-S130 WeakPolarHBondContact CA-O 3.38Å; I59-V132 HydrophobicContact CB-CG2 4.49Å; I59-V132 HydrophobicContact CD1-CG2 4.05Å; I59-V132 HydrophobicContact CG1-CG2 4.15Å; I59-V132 HydrophobicContact CG2-CG2 3.58Å; I59-Y164 HydrophobicContact CD1-CD1 3.49Å; I59-Y164 VanDerWaalsContact CD1-CD1 3.49Å; I59-Y164 HydrophobicContact CD1-CE1 3.82Å
60L94.2Very high79.9Confident32 Ų3254 Ų5417%0.16829%0.289CS..PPolyproline II helixtrans-83.7119.7170.8-175.165.9000110.2L54 W129 S130 E131 L616L54-L60 HydrophobicContact CD2-CD1 3.99Å; L60-W129 HydrophobicContact CB-CE3 3.92Å; L60-W129 HydrophobicContact CB-CZ3 4.22Å; L60-W129 HydrophobicContact CD2-CE3 4.03Å; L60-W129 HydrophobicContact CD2-CH2 3.99Å; L60-W129 HydrophobicContact CD2-CZ3 3.47Å; L60-W129 VanDerWaalsContact CD2-CZ3 3.47Å; L60-W129 HydrophobicContact CG-CZ3 4.43Å; L60-S130 PolarHBondContact N-O 2.65Å; L60-E131 HydrophobicContact CB-CG 4.01Å; L60-E131 HydrophobicContact CD2-CG 4.18Å; L60-E131 HydrophobicContact CG-CG 4.31Å; L60-L616 HydrophobicContact CD1-CD2 4.39Å
61L86.9Confident79.3Confident73 Ų7356.4 Ų56.438%0.38230%0.301SS..PPolyproline II helixtrans-99123.2175.6-64.2179.1000110.5F55 I59F55-L61 HydrophobicContact CB-CD1 3.58Å; F55-L61 HydrophobicContact CB-CD2 4.44Å; F55-L61 HydrophobicContact CB-CG 3.69Å; F55-L61 HydrophobicContact CD1-CD1 4.15Å; F55-L61 HydrophobicContact CD1-CD2 4.1Å; F55-L61 HydrophobicContact CD1-CG 4.25Å; F55-L61 HydrophobicContact CD2-CD1 3.78Å; F55-L61 HydrophobicContact CE2-CD1 4.47Å; F55-L61 HydrophobicContact CG-CD1 3.58Å; F55-L61 HydrophobicContact CG-CD2 4.33Å; F55-L61 HydrophobicContact CG-CG 3.98Å; I59-L61 HydrophobicContact CG2-CD2 4.06Å
62Q68.8Low78.9Confident103 Ų10358.9 Ų58.948%0.48130%0.3SS..SBendtrans-92.9-55.7176.8-71.5-154.1-0.800114.3E131Q62-E131 VanDerWaalsContact CD-OE1 3.29Å; Q62-E131 WeakPolarHBondContact CG-OE1 3.44Å; Q62-E131 PolarHBondContact NE2-OE1 3.36Å
63N56.4Low78.6Confident160 Ų16057.8 Ų57.886%0.85630%0.295SS*.SBendtrans-151.2-13.3-174.6-74.7-56.2000115.6
64S57.9Low78.6Confident66 Ų6655.6 Ų55.646%0.46228%0.278SS..SBendtrans-155.9156.7175.450.30000110.2N66S64-N66 VanDerWaalsContact C-N 3.31Å; S64-N66 PolarHBondContact O-N 3.4Å; S64-N66 VanDerWaalsContact O-N 3.08Å; S64-N66 PolarHBondContact OG-ND2 3.12Å; S64-N66 PolarHBondContact OG-OD1 3.41Å
65R58.8Low78.7Confident138 Ų13855 Ų5552%0.52127%0.274SS..  trans-81.483.8171.7-61.5-175.7-178.1173.7-4.5108.3Y194 L198R65-Y194 VanDerWaalsContact NH1-CE1 3.3Å; R65-L198 HydrophobicContact CB-CD1 3.56Å; R65-L198 HydrophobicContact CB-CD2 4.03Å; R65-L198 HydrophobicContact CB-CG 4.47Å; R65-L198 HydrophobicContact CG-CD2 4.41Å; R65-L198 WeakPolarHBondContact O-CD1 3.13Å
66N53.9Low78.7Confident36 Ų3662.6 Ų62.619%0.19331%0.307CS..  trans-81.3112.8175.9-69-13.9000107.7S64 T73 V132 Q135 Y164S64-N66 VanDerWaalsContact C-N 3.31Å; S64-N66 PolarHBondContact O-N 3.4Å; S64-N66 VanDerWaalsContact O-N 3.08Å; S64-N66 PolarHBondContact OG-ND2 3.12Å; S64-N66 PolarHBondContact OG-OD1 3.41Å; N66-T73 HydrophobicContact CB-CG2 3.85Å; N66-V132 VanDerWaalsContact O-CG1 3.27Å; N66-V132 WeakPolarHBondContact O-CG1 3.49Å; N66-Q135 PolarHBondContact ND2-OE1 3.01Å; N66-Y164 PolarHBondContact O-OH 3.46Å; N66-Y164 VanDerWaalsContact O-OH 3.07Å
67G54Low78.8Confident7 Ų765.5 Ų65.57%0.07232%0.32CS..  trans-121.9168.1-177.100000113.9R69 D70 Y164G67-R69 PolarHBondContact O-N 3.17Å; G67-D70 PolarHBondContact O-N 3.02Å; G67-Y164 VanDerWaalsContact CA-CE2 3.49Å
68L60.4Low78.9Confident9 Ų967.8 Ų67.85%0.04733%0.334CS..THydrogen-bonded Turntrans-27.6-25176.1-155.879.3000117R74 G162 F163 T200 L202 M256L68-R74 PolarHBondContact O-NH2 3.42Å; L68-G162 WeakPolarHBondContact CA-O 3.49Å; L68-G162 WeakPolarHBondContact CB-O 3.35Å; L68-G162 VanDerWaalsContact CD1-O 3.31Å; L68-G162 WeakPolarHBondContact CD1-O 3.42Å; L68-G162 PolarHBondContact N-O 3.46Å; L68-F163 HydrophobicContact CD1-CD1 4.24Å; L68-F163 HydrophobicContact CD1-CD2 3.84Å; L68-F163 HydrophobicContact CD1-CE1 4.3Å; L68-F163 HydrophobicContact CD1-CE2 3.91Å; L68-F163 HydrophobicContact CD1-CG 3.99Å; L68-F163 HydrophobicContact CD1-CZ 4.13Å; L68-T200 HydrophobicContact CB-CG2 4.03Å; L68-T200 HydrophobicContact CD2-CG2 3.55Å; L68-T200 WeakPolarHBondContact CD2-O 3.48Å; L68-T200 HydrophobicContact CG-CG2 4.01Å; L68-L202 HydrophobicContact CD2-CD1 4.12Å; L68-L202 HydrophobicContact CD2-CG 4.11Å; L68-M256 HydrophobicContact CD1-CE 3.81Å; L68-M256 HydrophobicContact CD1-SD 3.22Å; L68-M256 WeakPolarHBondContact CD1-SD 3.18Å; L68-M256 HydrophobicContact CG-SD 3.62Å
69R64.6Low79Confident152 Ų15267.7 Ų67.757%0.57433%0.334SS*.THydrogen-bonded Turntrans-87.9-31.5-176.2-149.8-180-171.9-163.35.5115.7G67 P71 T200G67-R69 PolarHBondContact O-N 3.17Å; R69-P71 WeakPolarHBondContact O-CD 3.42Å; R69-T200 HydrophobicContact CB-CG2 4.42Å
70D76.5Confident79Confident61 Ų6168.1 Ų68.133%0.32634%0.336SS..  trans-75.5111.4-179.1-172.3-4.2000109.9G67 N72 T73G67-D70 PolarHBondContact O-N 3.02Å; D70-N72 PolarHBondContact O-N 2.85Å; D70-N72 VanDerWaalsContact O-N 3.15Å; D70-N72 VanDerWaalsContact OD1-CB 3.3Å; D70-N72 WeakPolarHBondContact OD1-CB 3.44Å; D70-N72 PolarHBondContact OD1-N 2.96Å; D70-N72 PolarHBondContact OD1-ND2 3.4Å; D70-T73 HydrophobicContact CB-CG2 4.09Å; D70-T73 PolarHBondContact O-N 3.09Å; D70-T73 VanDerWaalsContact O-N 3.16Å; D70-T73 PolarHBondContact O-OG1 3.36Å
71P81.4Confident79.2Confident86 Ų8667.7 Ų67.756%0.55833%0.333SS*.G310 helixtrans-64.1-19.6178.8-19.134.6000112.8R69 T73R69-P71 WeakPolarHBondContact O-CD 3.42Å; P71-T73 VanDerWaalsContact C-N 3.32Å
72N85.6Confident79.7Confident114 Ų11464.8 Ų64.861%0.6132%0.317SS*.G310 helixtrans-70.4-30.9177.9-59.1-56.6000111.5D70 R74 H136D70-N72 PolarHBondContact O-N 2.85Å; D70-N72 VanDerWaalsContact O-N 3.15Å; D70-N72 VanDerWaalsContact OD1-CB 3.3Å; D70-N72 WeakPolarHBondContact OD1-CB 3.44Å; D70-N72 PolarHBondContact OD1-N 2.96Å; D70-N72 PolarHBondContact OD1-ND2 3.4Å; N72-R74 PolarHBondContact O-N 3.25Å; N72-H136 PolarHBondContact O-CE1 2.98Å; N72-H136 PolarHBondContact O-NE2 3.14Å
73T88.1Confident81Confident9 Ų961 Ų616%0.05530%0.3CS..G310 helixtrans-87.617-178.164.50000112.2N66 D70 P71 G133 D134N66-T73 HydrophobicContact CB-CG2 3.85Å; D70-T73 HydrophobicContact CB-CG2 4.09Å; D70-T73 PolarHBondContact O-N 3.09Å; D70-T73 VanDerWaalsContact O-N 3.16Å; D70-T73 PolarHBondContact O-OG1 3.36Å; P71-T73 VanDerWaalsContact C-N 3.32Å; T73-G133 CarbonylContact O-C 3.58Å; T73-G133 WeakPolarHBondContact O-CA 3.34Å; T73-D134 PolarHBondContact O-N 3.11Å
74R91.8Very high82.7Confident68 Ų6853.3 Ų53.326%0.25726%0.259SS..SBendtrans-94.8129.8178.2-65.3-178.1-176.3179.70.4110.4L68 N72 M256 Y257L68-R74 PolarHBondContact O-NH2 3.42Å; N72-R74 PolarHBondContact O-N 3.25Å; R74-M256 PolarHBondContact NH1-O 2.71Å; R74-Y257 HydrophobicContact CB-CE1 4Å
75W95.5Very high84.2Confident11 Ų1154 Ų544%0.04226%0.258CS..PPolyproline II helixtrans-55.4144.1170.8-72.395.4000113.5F77 I79 S118 I120 D134 Q139 A160 Y257W75-F77 HydrophobicContact CB-CD1 4.35Å; W75-F77 HydrophobicContact CB-CE1 3.95Å; W75-I79 HydrophobicContact CB-CD1 3.93Å; W75-I79 HydrophobicContact CB-CG1 3.98Å; W75-I79 HydrophobicContact CD2-CD1 4.2Å; W75-I79 HydrophobicContact CD2-CG1 4.3Å; W75-I79 HydrophobicContact CD2-CG2 4.07Å; W75-I79 HydrophobicContact CE3-CG1 4.36Å; W75-I79 HydrophobicContact CE3-CG2 3.76Å; W75-I79 HydrophobicContact CG-CD1 3.82Å; W75-I79 HydrophobicContact CG-CG1 4.15Å; W75-I79 HydrophobicContact CH2-CG2 4.45Å; W75-I79 HydrophobicContact CZ3-CG2 3.97Å; W75-S118 WeakPolarHBondContact CH2-OG 3.22Å; W75-S118 WeakPolarHBondContact CZ3-OG 3.08Å; W75-I120 HydrophobicContact CH2-CG1 3.75Å; W75-I120 HydrophobicContact CZ2-CD1 3.97Å; W75-I120 HydrophobicContact CZ2-CG1 3.51Å; W75-D134 HydrophobicContact CD2-CB 3.73Å; W75-D134 HydrophobicContact CE3-CB 4.25Å; W75-D134 HydrophobicContact CG-CB 3.92Å; W75-D134 HydrophobicContact CZ2-CB 4.2Å; W75-Q139 HydrophobicContact CH2-CG 4.46Å; W75-Q139 HydrophobicContact CZ2-CG 4.1Å; W75-A160 PolarHBondContact NE1-O 2.85Å; W75-Y257 PolarHBondContact N-OH 3.1Å; W75-Y257 WeakPolarHBondContact O-CE1 3.49Å
76K95.3Very high85.8Confident181 Ų18150.7 Ų50.779%0.78725%0.251SS*.PPolyproline II helixtrans-92.3135.2162.5-65.5-178.6-176.7174.10108.9P78K76-P78 CarbonylContact O-C 3.57Å
77F95.9Very high87.6Confident61 Ų6149.4 Ų49.427%0.26824%0.243SC..SBendtrans-92.7147-179.8-55.3-31.1000112.3W75 I79 C107 V108 L161 Y257W75-F77 HydrophobicContact CB-CD1 4.35Å; W75-F77 HydrophobicContact CB-CE1 3.95Å; F77-I79 HydrophobicContact CD1-CD1 4.17Å; F77-I79 HydrophobicContact CD1-CG1 3.66Å; F77-I79 HydrophobicContact CE1-CD1 3.9Å; F77-I79 HydrophobicContact CE1-CG1 3.91Å; F77-C107 WeakPolarHBondContact CD2-O 3.22Å; F77-V108 HydrophobicContact CE1-CB 4.49Å; F77-V108 HydrophobicContact CE1-CG1 4.06Å; F77-V108 HydrophobicContact CE1-CG2 4.31Å; F77-V108 HydrophobicContact CE2-CB 4.33Å; F77-V108 HydrophobicContact CE2-CG2 3.9Å; F77-V108 HydrophobicContact CZ-CB 4.15Å; F77-V108 HydrophobicContact CZ-CG1 4.18Å; F77-V108 HydrophobicContact CZ-CG2 3.61Å; F77-L161 HydrophobicContact CE1-CD2 3.9Å; F77-L161 HydrophobicContact CZ-CD2 4.07Å; F77-Y257 HydrophobicContact CD2-CD1 4.44Å; F77-Y257 HydrophobicContact CE1-CD1 4.12Å; F77-Y257 AromaticContact CE1-CE1 3.8Å; F77-Y257 HydrophobicContact CE1-CE1 3.8Å; F77-Y257 AromaticContact CE2-CD1 3.42Å; F77-Y257 HydrophobicContact CE2-CD1 3.42Å; F77-Y257 VanDerWaalsContact CE2-CD1 3.42Å; F77-Y257 HydrophobicContact CE2-CD2 4.28Å; F77-Y257 AromaticContact CE2-CE1 3.98Å; F77-Y257 HydrophobicContact CE2-CE1 3.98Å; F77-Y257 AromaticContact CE2-CG 3.58Å; F77-Y257 HydrophobicContact CE2-CG 3.58Å; F77-Y257 AromaticContact CZ-CD1 3.21Å; F77-Y257 HydrophobicContact CZ-CD1 3.21Å; F77-Y257 AromaticContact CZ-CD2 3.81Å; F77-Y257 HydrophobicContact CZ-CD2 3.81Å; F77-Y257 AromaticContact CZ-CE1 3.29Å; F77-Y257 HydrophobicContact CZ-CE1 3.29Å; F77-Y257 AromaticContact CZ-CE2 3.84Å; F77-Y257 HydrophobicContact CZ-CE2 3.84Å; F77-Y257 AromaticContact CZ-CG 3.48Å; F77-Y257 HydrophobicContact CZ-CG 3.48Å; F77-Y257 VanDerWaalsContact CZ-CG 3.48Å; F77-Y257 AromaticContact CZ-CZ 3.59Å
78P97.6Very high89.4Confident52 Ų5250.7 Ų50.734%0.33826%0.257SS..SBendcis-72.7144.1-4.330.7-36.3000113K76 P80 D109 K111K76-P78 CarbonylContact O-C 3.57Å; P78-P80 WeakPolarHBondContact O-CD 3.42Å; P78-D109 CarbonylContact C-O 3.47Å; P78-D109 WeakPolarHBondContact CA-O 3.36Å; P78-D109 HydrophobicContact CB-CB 4.02Å; P78-K111 HydrophobicContact CB-CB 4.13Å; P78-K111 HydrophobicContact CB-CG 4Å; P78-K111 HydrophobicContact CG-CB 4.15Å; P78-K111 HydrophobicContact CG-CD 3.73Å; P78-K111 HydrophobicContact CG-CG 3.78Å
79I98.4Very high91Very high1 Ų151.7 Ų51.71%0.00526%0.262CS..EExtended strand (participates in β ladder)trans-70.9121.4177.5-55.9-175.9000109.2W75 F77 V108 D109 F110 K111 I120 L161W75-I79 HydrophobicContact CB-CD1 3.93Å; W75-I79 HydrophobicContact CB-CG1 3.98Å; W75-I79 HydrophobicContact CD2-CD1 4.2Å; W75-I79 HydrophobicContact CD2-CG1 4.3Å; W75-I79 HydrophobicContact CD2-CG2 4.07Å; W75-I79 HydrophobicContact CE3-CG1 4.36Å; W75-I79 HydrophobicContact CE3-CG2 3.76Å; W75-I79 HydrophobicContact CG-CD1 3.82Å; W75-I79 HydrophobicContact CG-CG1 4.15Å; W75-I79 HydrophobicContact CH2-CG2 4.45Å; W75-I79 HydrophobicContact CZ3-CG2 3.97Å; F77-I79 HydrophobicContact CD1-CD1 4.17Å; F77-I79 HydrophobicContact CD1-CG1 3.66Å; F77-I79 HydrophobicContact CE1-CD1 3.9Å; F77-I79 HydrophobicContact CE1-CG1 3.91Å; I79-V108 HydrophobicContact CD1-CG1 4.31Å; I79-D109 PolarHBondContact N-O 2.97Å; I79-F110 HydrophobicContact CB-CD1 3.89Å; I79-F110 HydrophobicContact CB-CE1 4.12Å; I79-F110 HydrophobicContact CD1-CE1 3.9Å; I79-F110 HydrophobicContact CD1-CZ 4.37Å; I79-F110 HydrophobicContact CG1-CE1 4.42Å; I79-F110 HydrophobicContact CG2-CD1 4.37Å; I79-F110 HydrophobicContact CG2-CE1 4.46Å; I79-F110 CarbonylContact O-C 3.49Å; I79-F110 WeakPolarHBondContact O-CA 3.48Å; I79-K111 PolarHBondContact O-N 2.82Å; I79-I120 HydrophobicContact CG2-CD1 3.85Å; I79-I120 HydrophobicContact CG2-CG1 4.01Å; I79-L161 HydrophobicContact CD1-CD2 3.79Å
80P98.1Very high92.5Very high10 Ų1045.5 Ų45.57%0.06524%0.24CC..EExtended strand (participates in β ladder)trans-70.2133.9173.7-12.728.2000110.5P78 K111 Y113 E116 Y119 I120P78-P80 WeakPolarHBondContact O-CD 3.42Å; P80-K111 CarbonylContact C-O 3.46Å; P80-K111 VanDerWaalsContact CA-O 3.26Å; P80-K111 WeakPolarHBondContact CA-O 3.49Å; P80-Y113 HydrophobicContact CB-CD2 4.25Å; P80-E116 HydrophobicContact CB-CB 4.29Å; P80-E116 HydrophobicContact CB-CG 4.16Å; P80-E116 HydrophobicContact CG-CB 3.81Å; P80-E116 HydrophobicContact CG-CG 3.55Å; P80-Y119 CarbonylContact O-C 3.5Å; P80-Y119 VanDerWaalsContact O-CA 3.28Å; P80-Y119 WeakPolarHBondContact O-CA 3.4Å; P80-Y119 VanDerWaalsContact O-CB 3.31Å; P80-Y119 WeakPolarHBondContact O-CB 3.11Å; P80-I120 PolarHBondContact O-N 3.37Å
81Y97.6Very high93.5Very high24 Ų2442.9 Ų42.99%0.09423%0.227CC..EExtended strand (participates in β ladder)trans-130.6156178.874.4-90.3000113.7L83 L96 F99 F110 K111 Y113 I120Y81-L83 HydrophobicContact CD2-CD2 4.06Å; Y81-L83 HydrophobicContact CD2-CG 3.97Å; Y81-L83 HydrophobicContact CE2-CD1 4.23Å; Y81-L83 HydrophobicContact CE2-CD2 4.28Å; Y81-L83 HydrophobicContact CE2-CG 3.84Å; Y81-L96 HydrophobicContact CE2-CD2 4.37Å; Y81-F99 AromaticContact CD1-CE2 3.66Å; Y81-F99 HydrophobicContact CD1-CE2 3.66Å; Y81-F99 HydrophobicContact CD1-CZ 4.15Å; Y81-F99 AromaticContact CD2-CE2 4Å; Y81-F99 HydrophobicContact CD2-CE2 4Å; Y81-F99 HydrophobicContact CD2-CZ 4.32Å; Y81-F99 HydrophobicContact CE1-CD2 4.26Å; Y81-F99 AromaticContact CE1-CE2 3.64Å; Y81-F99 HydrophobicContact CE1-CE2 3.64Å; Y81-F99 HydrophobicContact CE2-CE2 4.01Å; Y81-F99 AromaticContact CG-CE2 3.85Å; Y81-F99 HydrophobicContact CG-CE2 3.85Å; Y81-F99 HydrophobicContact CG-CZ 4.03Å; Y81-F99 AromaticContact CZ-CE2 3.84Å; Y81-F110 HydrophobicContact CD1-CB 3.79Å; Y81-F110 HydrophobicContact CE1-CB 3.98Å; Y81-K111 WeakPolarHBondContact CD1-O 3.41Å; Y81-K111 WeakPolarHBondContact CE1-O 3.27Å; Y81-K111 PolarHBondContact N-O 3.41Å; Y81-Y113 WeakPolarHBondContact O-CB 3.32Å; Y81-Y113 PolarHBondContact O-N 2.75Å; Y81-I120 CarbonylContact C-O 3.47Å; Y81-I120 WeakPolarHBondContact CA-O 3.43Å
82I96.5Very high94.2Very high11 Ų1139.1 Ų39.16%0.05620%0.202CC..EExtended strand (participates in β ladder)trans-126.4130.8167.9-59.6-179.2000108.4Y113 Y119 I120 I121 F122 V604 T606I82-Y113 HydrophobicContact CD1-CD1 3.79Å; I82-Y113 HydrophobicContact CD1-CE1 4.38Å; I82-Y113 HydrophobicContact CD1-CG 3.89Å; I82-Y113 VanDerWaalsContact CG1-CB 3.49Å; I82-Y113 HydrophobicContact CG1-CD1 4.2Å; I82-Y113 HydrophobicContact CG1-CG 3.91Å; I82-Y119 HydrophobicContact CD1-CD2 3.87Å; I82-Y119 HydrophobicContact CD1-CE2 3.56Å; I82-Y119 HydrophobicContact CG1-CD2 4.13Å; I82-Y119 HydrophobicContact CG1-CE2 4.32Å; I82-I120 PolarHBondContact N-O 3.1Å; I82-I121 HydrophobicContact CB-CG1 4.46Å; I82-I121 HydrophobicContact CB-CG2 4.11Å; I82-I121 HydrophobicContact CD1-CG1 4.46Å; I82-I121 HydrophobicContact CG2-CG2 4.19Å; I82-F122 PolarHBondContact O-N 3.07Å; I82-V604 HydrophobicContact CD1-CB 4.46Å; I82-V604 HydrophobicContact CD1-CG1 4.32Å; I82-T606 HydrophobicContact CG2-CG2 4.23Å
83L96.3Very high94.8Very high23 Ų2333.9 Ų33.912%0.1218%0.175CC..EExtended strand (participates in β ladder)trans-94.7109.5165.1-56.6-179.5000107.8Y81 L87 K92 I95 L96 F122 T602Y81-L83 HydrophobicContact CD2-CD2 4.06Å; Y81-L83 HydrophobicContact CD2-CG 3.97Å; Y81-L83 HydrophobicContact CE2-CD1 4.23Å; Y81-L83 HydrophobicContact CE2-CD2 4.28Å; Y81-L83 HydrophobicContact CE2-CG 3.84Å; L83-L87 HydrophobicContact CB-CD1 4.11Å; L83-L87 HydrophobicContact CD2-CD1 4.26Å; L83-K92 HydrophobicContact CB-CG 4.3Å; L83-K92 HydrophobicContact CD1-CB 4.06Å; L83-K92 HydrophobicContact CD1-CG 4.23Å; L83-I95 HydrophobicContact CD2-CB 4.32Å; L83-I95 HydrophobicContact CD2-CD1 3.93Å; L83-I95 HydrophobicContact CD2-CG2 3.86Å; L83-L96 HydrophobicContact CD1-CD2 4.31Å; L83-L96 HydrophobicContact CD1-CG 4.34Å; L83-F122 HydrophobicContact CD2-CB 3.94Å; L83-F122 HydrophobicContact CD2-CD2 4.03Å; L83-F122 HydrophobicContact CD2-CG 4.11Å; L83-T602 WeakPolarHBondContact O-CG2 3.15Å
84A92.9Very high95.2Very high0 Ų033.4 Ų33.40%017%0.172CC..  trans-72.6160.4-174.900000113.5N86 L87 K92 I121 F122 Q123 T606A84-N86 WeakPolarHBondContact CB-OD1 3.43Å; A84-N86 PolarHBondContact O-N 3.46Å; A84-L87 WeakPolarHBondContact O-CB 3.46Å; A84-L87 PolarHBondContact O-N 3.31Å; A84-L87 VanDerWaalsContact O-N 3.15Å; A84-K92 WeakPolarHBondContact O-CE 3.3Å; A84-I121 HydrophobicContact CB-CG2 4.3Å; A84-F122 WeakPolarHBondContact CB-O 3.48Å; A84-F122 PolarHBondContact N-O 2.85Å; A84-Q123 HydrophobicContact CB-CB 4.32Å; A84-Q123 HydrophobicContact CB-CG 3.69Å; A84-T606 HydrophobicContact CB-CG2 4.36Å
85D88.9Confident95.6Very high80 Ų8030.2 Ų30.243%0.42816%0.16SC..THydrogen-bonded Turntrans-64.8-26.9-177-67.9-57.7000113.1L87 T602 T606D85-L87 VanDerWaalsContact C-N 3.26Å; D85-L87 PolarHBondContact O-N 3.03Å; D85-T602 HydrophobicContact CB-CG2 4.24Å; D85-T602 VanDerWaalsContact CG-OG1 3.28Å; D85-T602 VanDerWaalsContact OD1-CB 3.29Å; D85-T602 WeakPolarHBondContact OD1-CB 3.23Å; D85-T602 WeakPolarHBondContact OD1-CG2 3.39Å; D85-T602 PolarHBondContact OD1-OG1 3.29Å; D85-T602 PolarHBondContact OD2-OG1 2.71Å; D85-T606 PolarHBondContact OD2-OG1 3Å
86N91.9Very high95.7Very high69 Ų6931.7 Ų31.737%0.36917%0.169SC..THydrogen-bonded Turntrans-79.6-4.3179.167.7-35.3000113.5A84 Q124A84-N86 WeakPolarHBondContact CB-OD1 3.43Å; A84-N86 PolarHBondContact O-N 3.46Å; N86-Q124 PolarHBondContact ND2-N 2.78Å; N86-Q124 PolarHBondContact ND2-O 2.99Å; N86-Q124 WeakPolarHBondContact O-CB 3.27Å; N86-Q124 PolarHBondContact O-OE1 3.24Å
87L92.6Very high95.8Very high8 Ų825 Ų254%0.04214%0.139CC..SBendtrans-74.8131.8170.9-74.8171.5000110.8L83 A84 D85 A91 K92 I95 F122 Q124 I143L83-L87 HydrophobicContact CB-CD1 4.11Å; L83-L87 HydrophobicContact CD2-CD1 4.26Å; A84-L87 WeakPolarHBondContact O-CB 3.46Å; A84-L87 PolarHBondContact O-N 3.31Å; A84-L87 VanDerWaalsContact O-N 3.15Å; D85-L87 VanDerWaalsContact C-N 3.26Å; D85-L87 PolarHBondContact O-N 3.03Å; L87-A91 HydrophobicContact CD2-CB 4.22Å; L87-K92 HydrophobicContact CB-CG 3.86Å; L87-K92 HydrophobicContact CD1-CG 4.21Å; L87-I95 HydrophobicContact CD1-CD1 3.93Å; L87-F122 HydrophobicContact CD1-CB 3.75Å; L87-F122 WeakPolarHBondContact CD1-O 3.15Å; L87-Q124 HydrophobicContact CD2-CB 4.25Å; L87-I143 HydrophobicContact CD2-CB 4.11Å
88G91.8Very high95.9Very high34 Ų3422.1 Ų22.135%0.35113%0.126SC..  trans-56.5148.8166.200000112.2N90 A91 K92G88-N90 VanDerWaalsContact C-N 3.25Å; G88-N90 PolarHBondContact O-N 2.93Å; G88-A91 WeakPolarHBondContact O-CB 3.25Å; G88-A91 PolarHBondContact O-N 2.77Å; G88-A91 VanDerWaalsContact O-N 3.12Å; G88-K92 PolarHBondContact O-N 2.81Å; G88-K92 VanDerWaalsContact O-N 3.15Å
89L94.6Very high96Very high31 Ų3119.7 Ų19.716%0.16211%0.11CC..Hα-helixtrans-59.5-37.4-177-169.759.8000112.4K92 G93 N503 T528 I596 L599L89-K92 PolarHBondContact O-N 3.31Å; L89-G93 PolarHBondContact O-N 3.28Å; L89-N503 HydrophobicContact CD2-CB 3.58Å; L89-N503 WeakPolarHBondContact CD2-OD1 3.25Å; L89-T528 HydrophobicContact CD2-CG2 4.17Å; L89-T528 HydrophobicContact CG-CG2 4.43Å; L89-I596 HydrophobicContact CD1-CD1 4.19Å; L89-I596 HydrophobicContact CD1-CG1 4.39Å; L89-I596 HydrophobicContact CD2-CD1 4.35Å; L89-I596 HydrophobicContact CD2-CG1 4.18Å; L89-I596 HydrophobicContact CG-CD1 3.69Å; L89-I596 HydrophobicContact CG-CG1 4.01Å; L89-I596 WeakPolarHBondContact O-CD1 3.37Å; L89-L599 HydrophobicContact CD1-CB 3.74Å
90N95.8Very high95.9Very high22 Ų2221 Ų2112%0.11812%0.117CC..Hα-helixtrans-61-46.9175.2-167.257.4000112.5G88 K92 G93 A94 D148 Q505 V526 F527 T528G88-N90 VanDerWaalsContact C-N 3.25Å; G88-N90 PolarHBondContact O-N 2.93Å; N90-K92 VanDerWaalsContact C-N 3.31Å; N90-K92 PolarHBondContact O-N 3.37Å; N90-G93 PolarHBondContact O-N 2.96Å; N90-A94 WeakPolarHBondContact O-CB 3.48Å; N90-A94 PolarHBondContact O-N 3.31Å; N90-D148 PolarHBondContact ND2-OD2 3.3Å; N90-Q505 PolarHBondContact O-NE2 3.09Å; N90-Q505 VanDerWaalsContact O-NE2 3.13Å; N90-Q505 PolarHBondContact OD1-NE2 2.72Å; N90-V526 PolarHBondContact ND2-O 2.91Å; N90-F527 WeakPolarHBondContact OD1-CA 3.27Å; N90-T528 VanDerWaalsContact CA-OG1 3.26Å; N90-T528 WeakPolarHBondContact CA-OG1 3.46Å; N90-T528 WeakPolarHBondContact CB-OG1 3.15Å; N90-T528 PolarHBondContact OD1-N 3.16Å; N90-T528 VanDerWaalsContact OD1-N 3.14Å; N90-T528 PolarHBondContact OD1-OG1 2.73Å
91A96.6Very high95.9Very high6 Ų621.9 Ų21.95%0.0512%0.12CC..Hα-helixtrans-59.6-42.1178.500000111.4L87 G88 G93 A94 I95 I143 D148L87-A91 HydrophobicContact CD2-CB 4.22Å; G88-A91 WeakPolarHBondContact O-CB 3.25Å; G88-A91 PolarHBondContact O-N 2.77Å; G88-A91 VanDerWaalsContact O-N 3.12Å; A91-G93 PolarHBondContact O-N 3.09Å; A91-A94 PolarHBondContact O-N 3.25Å; A91-I95 WeakPolarHBondContact O-CB 3.31Å; A91-I95 WeakPolarHBondContact O-CD1 3.43Å; A91-I95 WeakPolarHBondContact O-CG1 3.08Å; A91-I95 PolarHBondContact O-N 3.32Å; A91-I143 HydrophobicContact CB-CG2 4.06Å; A91-D148 HydrophobicContact CB-CB 3.85Å
92K97.1Very high95.9Very high6 Ų620.8 Ų20.83%0.02612%0.116CC..Hα-helixtrans-57.9-49.3175.7-66.8-176.8176.7178.50111.8L83 A84 L87 G88 L89 N90 I95 L96 L599L83-K92 HydrophobicContact CB-CG 4.3Å; L83-K92 HydrophobicContact CD1-CB 4.06Å; L83-K92 HydrophobicContact CD1-CG 4.23Å; A84-K92 WeakPolarHBondContact O-CE 3.3Å; L87-K92 HydrophobicContact CB-CG 3.86Å; L87-K92 HydrophobicContact CD1-CG 4.21Å; G88-K92 PolarHBondContact O-N 2.81Å; G88-K92 VanDerWaalsContact O-N 3.15Å; L89-K92 PolarHBondContact O-N 3.31Å; N90-K92 VanDerWaalsContact C-N 3.31Å; N90-K92 PolarHBondContact O-N 3.37Å; K92-I95 PolarHBondContact O-N 2.95Å; K92-L96 WeakPolarHBondContact O-CG 3.34Å; K92-L96 PolarHBondContact O-N 2.76Å; K92-L599 HydrophobicContact CB-CB 4.33Å; K92-L599 HydrophobicContact CB-CD1 4.18Å; K92-L599 HydrophobicContact CD-CB 4.23Å; K92-L599 WeakPolarHBondContact CD-O 3.44Å; K92-L599 PolarHBondContact NZ-O 2.98Å
93G96.8Very high96Very high4 Ų422.1 Ų22.14%0.04112%0.12CC..Hα-helixtrans-64.9-40.7176.900000112.9L89 N90 A91 I95 L96 Y97L89-G93 PolarHBondContact O-N 3.28Å; N90-G93 PolarHBondContact O-N 2.96Å; A91-G93 PolarHBondContact O-N 3.09Å; G93-I95 VanDerWaalsContact C-N 3.35Å; G93-I95 PolarHBondContact O-N 3.44Å; G93-L96 PolarHBondContact O-N 2.78Å; G93-Y97 PolarHBondContact O-N 3.37Å
94A97.9Very high96.1Very high0 Ų021.7 Ų21.70%012%0.118CC..Hα-helixtrans-64.4-36.3177.700000112.7N90 A91 Y97 A98 D148 I153N90-A94 WeakPolarHBondContact O-CB 3.48Å; N90-A94 PolarHBondContact O-N 3.31Å; A91-A94 PolarHBondContact O-N 3.25Å; A94-Y97 WeakPolarHBondContact O-CB 3.35Å; A94-Y97 PolarHBondContact O-N 3.04Å; A94-A98 PolarHBondContact O-N 2.85Å; A94-D148 WeakPolarHBondContact CB-O 3.26Å; A94-I153 HydrophobicContact CB-CD1 3.61Å
95I98.6Very high96.3Very high0 Ų021.9 Ų21.90%012%0.119CC..Hα-helixtrans-64.4-46.3173.9-68.4158.1000110.7L83 L87 A91 K92 G93 Y97 A98 F99 F122 I143 I153L83-I95 HydrophobicContact CD2-CB 4.32Å; L83-I95 HydrophobicContact CD2-CD1 3.93Å; L83-I95 HydrophobicContact CD2-CG2 3.86Å; L87-I95 HydrophobicContact CD1-CD1 3.93Å; A91-I95 WeakPolarHBondContact O-CB 3.31Å; A91-I95 WeakPolarHBondContact O-CD1 3.43Å; A91-I95 WeakPolarHBondContact O-CG1 3.08Å; A91-I95 PolarHBondContact O-N 3.32Å; K92-I95 PolarHBondContact O-N 2.95Å; G93-I95 VanDerWaalsContact C-N 3.35Å; G93-I95 PolarHBondContact O-N 3.44Å; I95-Y97 VanDerWaalsContact C-N 3.26Å; I95-Y97 PolarHBondContact O-N 3.18Å; I95-A98 WeakPolarHBondContact O-CB 3.34Å; I95-A98 PolarHBondContact O-N 2.97Å; I95-F99 HydrophobicContact CG2-CD1 4.29Å; I95-F99 HydrophobicContact CG2-CE1 3.62Å; I95-F99 HydrophobicContact CG2-CE2 3.96Å; I95-F99 HydrophobicContact CG2-CZ 3.43Å; I95-F99 VanDerWaalsContact CG2-CZ 3.43Å; I95-F99 WeakPolarHBondContact O-CD1 2.99Å; I95-F99 WeakPolarHBondContact O-CG 3.32Å; I95-F99 PolarHBondContact O-N 3.22Å; I95-F122 HydrophobicContact CD1-CB 3.8Å; I95-F122 HydrophobicContact CD1-CD1 3.73Å; I95-F122 HydrophobicContact CD1-CG 3.93Å; I95-F122 HydrophobicContact CG1-CD1 4.04Å; I95-F122 HydrophobicContact CG1-CE1 4.47Å; I95-F122 HydrophobicContact CG2-CD1 4.02Å; I95-F122 HydrophobicContact CG2-CD2 4.42Å; I95-F122 HydrophobicContact CG2-CE1 3.95Å; I95-F122 HydrophobicContact CG2-CE2 4.37Å; I95-F122 HydrophobicContact CG2-CG 4.26Å; I95-F122 HydrophobicContact CG2-CZ 4.14Å; I95-I143 HydrophobicContact CD1-CG1 4.1Å; I95-I143 HydrophobicContact CG1-CG1 4.35Å; I95-I153 HydrophobicContact CB-CG2 4.46Å; I95-I153 HydrophobicContact CG1-CD1 3.99Å; I95-I153 HydrophobicContact CG1-CG1 4.34Å; I95-I153 HydrophobicContact CG1-CG2 4Å
96L97.9Very high96.7Very high43 Ų4318.1 Ų18.123%0.22510%0.098CC..Hα-helixtrans-63.8-34.3176.6-64.2-179.9000111.9Y81 L83 K92 G93 F99 E100 L599Y81-L96 HydrophobicContact CE2-CD2 4.37Å; L83-L96 HydrophobicContact CD1-CD2 4.31Å; L83-L96 HydrophobicContact CD1-CG 4.34Å; K92-L96 WeakPolarHBondContact O-CG 3.34Å; K92-L96 PolarHBondContact O-N 2.76Å; G93-L96 PolarHBondContact O-N 2.78Å; L96-F99 HydrophobicContact CD2-CD2 3.81Å; L96-F99 HydrophobicContact CD2-CE2 3.97Å; L96-F99 WeakPolarHBondContact O-CB 3.39Å; L96-F99 PolarHBondContact O-N 3.28Å; L96-E100 PolarHBondContact O-N 3.12Å; L96-L599 HydrophobicContact CD1-CD1 3.77Å; L96-L599 HydrophobicContact CD1-CD2 3.77Å; L96-L599 HydrophobicContact CD1-CG 4.44Å
97Y97.7Very high96.9Very high41 Ų4115.9 Ų15.916%0.1619%0.088CC..Hα-helixtrans-65.3-43.1173-179.5-134.8000112.1G93 A94 I95 F99 E100 M101 K150 I507 S524 V526G93-Y97 PolarHBondContact O-N 3.37Å; A94-Y97 WeakPolarHBondContact O-CB 3.35Å; A94-Y97 PolarHBondContact O-N 3.04Å; I95-Y97 VanDerWaalsContact C-N 3.26Å; I95-Y97 PolarHBondContact O-N 3.18Å; Y97-F99 VanDerWaalsContact C-N 3.32Å; Y97-F99 PolarHBondContact O-N 3.4Å; Y97-E100 WeakPolarHBondContact O-CB 3.16Å; Y97-E100 PolarHBondContact O-N 3.42Å; Y97-E100 VanDerWaalsContact O-N 3.16Å; Y97-M101 HydrophobicContact CD2-CE 4.39Å; Y97-M101 HydrophobicContact CE2-CE 3.87Å; Y97-M101 PolarHBondContact O-N 2.97Å; Y97-K150 HydrophobicContact CD1-CB 4.24Å; Y97-K150 HydrophobicContact CD1-CD 3.94Å; Y97-K150 HydrophobicContact CD1-CG 4.04Å; Y97-K150 HydrophobicContact CE1-CB 4.3Å; Y97-K150 HydrophobicContact CE1-CD 3.47Å; Y97-K150 VanDerWaalsContact CE1-CD 3.47Å; Y97-K150 HydrophobicContact CE1-CG 4.07Å; Y97-I507 HydrophobicContact CD1-CD1 4.43Å; Y97-I507 HydrophobicContact CD2-CD1 4.27Å; Y97-I507 HydrophobicContact CE1-CG2 3.99Å; Y97-I507 HydrophobicContact CG-CD1 4.2Å; Y97-S524 PolarHBondContact OH-OG 2.77Å; Y97-S524 VanDerWaalsContact OH-OG 3.09Å; Y97-V526 HydrophobicContact CD1-CG2 4.09Å; Y97-V526 HydrophobicContact CE1-CG2 4.3Å
98A98.4Very high97.2Very high0 Ų015.5 Ų15.50%09%0.086CC..Hα-helixtrans-61.1-38.6173.200000112.2A94 I95 E100 M101 F102 I153 E154A94-A98 PolarHBondContact O-N 2.85Å; I95-A98 WeakPolarHBondContact O-CB 3.34Å; I95-A98 PolarHBondContact O-N 2.97Å; A98-E100 VanDerWaalsContact C-N 3.26Å; A98-E100 PolarHBondContact O-N 3.39Å; A98-M101 WeakPolarHBondContact O-CB 3.47Å; A98-M101 PolarHBondContact O-N 3.22Å; A98-F102 WeakPolarHBondContact O-CD2 3.36Å; A98-F102 PolarHBondContact O-N 3.1Å; A98-I153 HydrophobicContact CB-CB 4.17Å; A98-I153 HydrophobicContact CB-CG2 3.75Å; A98-E154 HydrophobicContact CB-CG 4.04Å
99F98.6Very high97.5Very high0 Ų015.6 Ų15.60%08%0.078CC..Hα-helixtrans-58.8-37.2174.5-65.9-10.5000112.6Y81 I95 L96 Y97 M101 F102 R103 F110 F122 I157Y81-F99 AromaticContact CD1-CE2 3.66Å; Y81-F99 HydrophobicContact CD1-CE2 3.66Å; Y81-F99 HydrophobicContact CD1-CZ 4.15Å; Y81-F99 AromaticContact CD2-CE2 4Å; Y81-F99 HydrophobicContact CD2-CE2 4Å; Y81-F99 HydrophobicContact CD2-CZ 4.32Å; Y81-F99 HydrophobicContact CE1-CD2 4.26Å; Y81-F99 AromaticContact CE1-CE2 3.64Å; Y81-F99 HydrophobicContact CE1-CE2 3.64Å; Y81-F99 HydrophobicContact CE2-CE2 4.01Å; Y81-F99 AromaticContact CG-CE2 3.85Å; Y81-F99 HydrophobicContact CG-CE2 3.85Å; Y81-F99 HydrophobicContact CG-CZ 4.03Å; Y81-F99 AromaticContact CZ-CE2 3.84Å; I95-F99 HydrophobicContact CG2-CD1 4.29Å; I95-F99 HydrophobicContact CG2-CE1 3.62Å; I95-F99 HydrophobicContact CG2-CE2 3.96Å; I95-F99 HydrophobicContact CG2-CZ 3.43Å; I95-F99 VanDerWaalsContact CG2-CZ 3.43Å; I95-F99 WeakPolarHBondContact O-CD1 2.99Å; I95-F99 WeakPolarHBondContact O-CG 3.32Å; I95-F99 PolarHBondContact O-N 3.22Å; L96-F99 HydrophobicContact CD2-CD2 3.81Å; L96-F99 HydrophobicContact CD2-CE2 3.97Å; L96-F99 WeakPolarHBondContact O-CB 3.39Å; L96-F99 PolarHBondContact O-N 3.28Å; Y97-F99 VanDerWaalsContact C-N 3.32Å; Y97-F99 PolarHBondContact O-N 3.4Å; F99-M101 VanDerWaalsContact C-N 3.29Å; F99-M101 PolarHBondContact O-N 2.73Å; F99-F102 PolarHBondContact O-N 3.23Å; F99-R103 WeakPolarHBondContact O-CG 3.28Å; F99-R103 PolarHBondContact O-N 2.76Å; F99-F110 HydrophobicContact CB-CD2 3.79Å; F99-F110 HydrophobicContact CB-CE2 4.32Å; F99-F110 HydrophobicContact CB-CG 4.4Å; F99-F110 HydrophobicContact CD1-CB 4.44Å; F99-F110 AromaticContact CD1-CD1 3.94Å; F99-F110 HydrophobicContact CD1-CD1 3.94Å; F99-F110 AromaticContact CD1-CD2 3.49Å; F99-F110 HydrophobicContact CD1-CD2 3.49Å; F99-F110 VanDerWaalsContact CD1-CD2 3.49Å; F99-F110 HydrophobicContact CD1-CE1 4.04Å; F99-F110 AromaticContact CD1-CE2 3.61Å; F99-F110 HydrophobicContact CD1-CE2 3.61Å; F99-F110 AromaticContact CD1-CG 3.68Å; F99-F110 HydrophobicContact CD1-CG 3.68Å; F99-F110 AromaticContact CD1-CZ 3.89Å; F99-F110 HydrophobicContact CD1-CZ 3.89Å; F99-F110 HydrophobicContact CD2-CB 3.75Å; F99-F110 HydrophobicContact CD2-CD2 4.15Å; F99-F110 AromaticContact CD2-CG 3.9Å; F99-F110 HydrophobicContact CD2-CG 3.9Å; F99-F110 AromaticContact CE1-CD1 3.6Å; F99-F110 HydrophobicContact CE1-CD1 3.6Å; F99-F110 HydrophobicContact CE1-CD2 4.05Å; F99-F110 AromaticContact CE1-CE1 3.71Å; F99-F110 HydrophobicContact CE1-CE1 3.71Å; F99-F110 HydrophobicContact CE1-CE2 4.16Å; F99-F110 AromaticContact CE1-CG 3.79Å; F99-F110 HydrophobicContact CE1-CG 3.79Å; F99-F110 HydrophobicContact CE1-CZ 4.01Å; F99-F110 HydrophobicContact CE2-CB 3.86Å; F99-F110 HydrophobicContact CE2-CD1 4.26Å; F99-F110 HydrophobicContact CE2-CG 4.01Å; F99-F110 HydrophobicContact CG-CB 4.06Å; F99-F110 HydrophobicContact CG-CD1 4.41Å; F99-F110 AromaticContact CG-CD2 3.55Å; F99-F110 HydrophobicContact CG-CD2 3.55Å; F99-F110 HydrophobicContact CG-CE2 4.1Å; F99-F110 AromaticContact CG-CG 3.74Å; F99-F110 HydrophobicContact CG-CG 3.74Å; F99-F110 HydrophobicContact CZ-CB 4.24Å; F99-F110 AromaticContact CZ-CD1 3.77Å; F99-F110 HydrophobicContact CZ-CD1 3.77Å; F99-F110 HydrophobicContact CZ-CE1 4.3Å; F99-F110 AromaticContact CZ-CG 3.95Å; F99-F110 HydrophobicContact CZ-CG 3.95Å; F99-F122 HydrophobicContact CE1-CE2 4.13Å; F99-F122 AromaticContact CE1-CZ 3.75Å; F99-F122 HydrophobicContact CE1-CZ 3.75Å; F99-F122 AromaticContact CZ-CE2 3.69Å; F99-F122 HydrophobicContact CZ-CE2 3.69Å; F99-F122 AromaticContact CZ-CZ 3.8Å; F99-F122 HydrophobicContact CZ-CZ 3.8Å; F99-I157 HydrophobicContact CD1-CD1 4.03Å; F99-I157 HydrophobicContact CE1-CD1 3.76Å
100E97.4Very high97.6Very high30 Ų3014.3 Ų14.314%0.147%0.071CC..Hα-helixtrans-65.9-31.3176.2-67.4-65.1138.500112.1L96 Y97 A98 R103 L104 R339L96-E100 PolarHBondContact O-N 3.12Å; Y97-E100 WeakPolarHBondContact O-CB 3.16Å; Y97-E100 PolarHBondContact O-N 3.42Å; Y97-E100 VanDerWaalsContact O-N 3.16Å; A98-E100 VanDerWaalsContact C-N 3.26Å; A98-E100 PolarHBondContact O-N 3.39Å; E100-R103 PolarHBondContact O-N 3.32Å; E100-R103 IonicContact OE1-CZ 2.81Å; E100-R103 IonicContact OE1-NH1 3.95Å; E100-R103 PolarHBondContact OE1-NH1 3.4Å; E100-L104 VanDerWaalsContact O-CB 3.26Å; E100-L104 WeakPolarHBondContact O-CB 3.48Å; E100-L104 PolarHBondContact O-N 3.37Å; E100-R339 IonicContact OE1-CZ 2.73Å; E100-R339 IonicContact OE1-NH1 3.42Å; E100-R339 PolarHBondContact OE1-NH1 3.06Å; E100-R339 IonicContact OE1-NH2 3.53Å; E100-R339 PolarHBondContact OE1-NH2 2.84Å; E100-R339 IonicContact OE2-CZ 3.59Å; E100-R339 IonicContact OE2-NH1 3.99Å; E100-R339 PolarHBondContact OE2-NH1 2.85Å; E100-R339 IonicContact OE2-NH2 3.73Å
101M97.9Very high97.7Very high27 Ų2715.8 Ų15.813%0.1338%0.077CC..Hα-helixtrans-68.2-43174.4-62.9-5498.400111.6Y97 A98 F99 R103 L104 K105 K150 E154 F245Y97-M101 HydrophobicContact CD2-CE 4.39Å; Y97-M101 HydrophobicContact CE2-CE 3.87Å; Y97-M101 PolarHBondContact O-N 2.97Å; A98-M101 WeakPolarHBondContact O-CB 3.47Å; A98-M101 PolarHBondContact O-N 3.22Å; F99-M101 VanDerWaalsContact C-N 3.29Å; F99-M101 PolarHBondContact O-N 2.73Å; M101-R103 PolarHBondContact O-N 3.05Å; M101-L104 PolarHBondContact O-N 3.48Å; M101-K105 WeakPolarHBondContact O-CB 3.13Å; M101-K105 WeakPolarHBondContact O-CG 3.44Å; M101-K105 PolarHBondContact O-N 3.02Å; M101-K150 HydrophobicContact CG-CD 3.97Å; M101-E154 VanDerWaalsContact CB-OE1 3.27Å; M101-E154 WeakPolarHBondContact CB-OE1 2.98Å; M101-E154 VanDerWaalsContact CG-OE1 3.23Å; M101-E154 WeakPolarHBondContact CG-OE1 3.43Å; M101-F245 HydrophobicContact CB-CE2 4.18Å
102F98.5Very high97.6Very high1 Ų117.9 Ų17.90%0.0049%0.09CC..Hα-helixtrans-58.9-46.2172.3-82.2-76.8000112A98 F99 L104 K105 S106 V108 F110 E154 I157 L158 L161 F245 L253A98-F102 WeakPolarHBondContact O-CD2 3.36Å; A98-F102 PolarHBondContact O-N 3.1Å; F99-F102 PolarHBondContact O-N 3.23Å; F102-L104 VanDerWaalsContact C-N 3.29Å; F102-L104 PolarHBondContact O-N 3.3Å; F102-K105 PolarHBondContact O-N 3.19Å; F102-S106 CarbonylContact O-C 3.59Å; F102-S106 WeakPolarHBondContact O-CA 3.33Å; F102-S106 WeakPolarHBondContact O-CB 3.34Å; F102-S106 PolarHBondContact O-N 2.81Å; F102-S106 PolarHBondContact O-OG 2.93Å; F102-V108 HydrophobicContact CB-CB 4.18Å; F102-V108 HydrophobicContact CB-CG1 4.38Å; F102-V108 HydrophobicContact CD1-CB 3.97Å; F102-V108 HydrophobicContact CD1-CG1 4.1Å; F102-V108 HydrophobicContact CD1-CG2 4.13Å; F102-V108 HydrophobicContact CG-CB 4.42Å; F102-V108 HydrophobicContact CG-CG1 4.39Å; F102-F110 HydrophobicContact CB-CE2 3.9Å; F102-F110 HydrophobicContact CD2-CE2 4.05Å; F102-F110 HydrophobicContact CD2-CZ 4.28Å; F102-F110 HydrophobicContact CG-CE2 4.04Å; F102-F110 HydrophobicContact CG-CZ 4.45Å; F102-E154 HydrophobicContact CE2-CG 4.32Å; F102-I157 HydrophobicContact CD2-CD1 4.47Å; F102-I157 HydrophobicContact CD2-CG2 4.24Å; F102-I157 HydrophobicContact CE1-CG2 4.08Å; F102-I157 HydrophobicContact CE2-CB 3.72Å; F102-I157 HydrophobicContact CE2-CD1 3.87Å; F102-I157 HydrophobicContact CE2-CG1 4.41Å; F102-I157 HydrophobicContact CE2-CG2 3.41Å; F102-I157 VanDerWaalsContact CE2-CG2 3.41Å; F102-I157 HydrophobicContact CZ-CB 3.74Å; F102-I157 HydrophobicContact CZ-CG2 3.3Å; F102-L158 HydrophobicContact CE1-CD2 4.29Å; F102-L158 HydrophobicContact CZ-CG 4.47Å; F102-L161 HydrophobicContact CD1-CD1 4.25Å; F102-L161 HydrophobicContact CE1-CD1 3.52Å; F102-L161 HydrophobicContact CZ-CD1 4.05Å; F102-F245 HydrophobicContact CD1-CZ 4.03Å; F102-F245 HydrophobicContact CD2-CZ 4.04Å; F102-F245 AromaticContact CE1-CE1 3.96Å; F102-F245 HydrophobicContact CE1-CE1 3.96Å; F102-F245 HydrophobicContact CE1-CE2 4.43Å; F102-F245 AromaticContact CE1-CZ 3.56Å; F102-F245 HydrophobicContact CE1-CZ 3.56Å; F102-F245 HydrophobicContact CE2-CE1 4.36Å; F102-F245 HydrophobicContact CE2-CE2 4.49Å; F102-F245 AromaticContact CE2-CZ 3.57Å; F102-F245 HydrophobicContact CE2-CZ 3.57Å; F102-F245 HydrophobicContact CG-CZ 4.25Å; F102-F245 AromaticContact CZ-CE1 3.72Å; F102-F245 HydrophobicContact CZ-CE1 3.72Å; F102-F245 HydrophobicContact CZ-CE2 4.43Å; F102-F245 AromaticContact CZ-CZ 3.31Å; F102-F245 HydrophobicContact CZ-CZ 3.31Å; F102-L253 HydrophobicContact CD1-CD2 4.09Å; F102-L253 HydrophobicContact CE1-CD2 3.97Å
103R98.1Very high97.6Very high39 Ų3920.4 Ų20.415%0.14710%0.1CC..Hα-helixtrans-62.9-34178-74.1169.5174148.87.4113.1F99 E100 M101 D109 F110 H263 T264F99-R103 WeakPolarHBondContact O-CG 3.28Å; F99-R103 PolarHBondContact O-N 2.76Å; E100-R103 PolarHBondContact O-N 3.32Å; E100-R103 IonicContact OE1-CZ 2.81Å; E100-R103 IonicContact OE1-NH1 3.95Å; E100-R103 PolarHBondContact OE1-NH1 3.4Å; M101-R103 PolarHBondContact O-N 3.05Å; R103-D109 IonicContact CZ-OD1 2.63Å; R103-D109 IonicContact NE-OD1 2.8Å; R103-D109 PolarHBondContact NE-OD1 3.41Å; R103-D109 IonicContact NH2-OD1 2.82Å; R103-D109 PolarHBondContact NH2-OD1 2.79Å; R103-D109 VanDerWaalsContact NH2-OD1 3.16Å; R103-F110 PolarHBondContact NH2-O 2.96Å; R103-H263 HydrophobicContact CB-CB 3.93Å; R103-H263 HydrophobicContact CG-CB 4.18Å; R103-H263 WeakPolarHBondContact O-CA 3.41Å; R103-H263 WeakPolarHBondContact O-CB 3.36Å; R103-H263 PolarHBondContact O-N 3.3Å; R103-T264 HydrophobicContact CB-CG2 3.93Å; R103-T264 PolarHBondContact O-N 3.29Å; R103-T264 PolarHBondContact O-OG1 3.09Å
104L97.5Very high97.4Very high14 Ų1427.5 Ų27.57%0.07313%0.132CC..Hα-helixtrans-75.4-38179.3176.962.3000112.4E100 M101 F102 T262 T264 L265 T427 V517E100-L104 VanDerWaalsContact O-CB 3.26Å; E100-L104 WeakPolarHBondContact O-CB 3.48Å; E100-L104 PolarHBondContact O-N 3.37Å; M101-L104 PolarHBondContact O-N 3.48Å; F102-L104 VanDerWaalsContact C-N 3.29Å; F102-L104 PolarHBondContact O-N 3.3Å; L104-T262 WeakPolarHBondContact O-CB 3.49Å; L104-T262 WeakPolarHBondContact O-CG2 3.24Å; L104-T264 WeakPolarHBondContact CA-OG1 3.29Å; L104-T264 PolarHBondContact N-OG1 2.8Å; L104-L265 HydrophobicContact CD1-CB 4.32Å; L104-T427 HydrophobicContact CD1-CG2 3.59Å; L104-V517 HydrophobicContact CD1-CG1 4.31Å; L104-V517 HydrophobicContact CD1-CG2 4.48Å; L104-V517 HydrophobicContact CD2-CG2 4.13Å
105K97.6Very high97.2Very high5 Ų530 Ų302%0.02216%0.158CC..Hα-helixtrans-106-13.2-167.4-63.3177.6164.8-169.80114.3M101 F102 D244 F245 L250 N254 R518 R520M101-K105 WeakPolarHBondContact O-CB 3.13Å; M101-K105 WeakPolarHBondContact O-CG 3.44Å; M101-K105 PolarHBondContact O-N 3.02Å; F102-K105 PolarHBondContact O-N 3.19Å; K105-D244 IonicContact NZ-OD1 2.88Å; K105-D244 PolarHBondContact NZ-OD1 2.03Å; K105-D244 IonicContact NZ-OD2 3.23Å; K105-D244 PolarHBondContact NZ-OD2 3.39Å; K105-F245 HydrophobicContact CD-CD2 3.92Å; K105-L250 HydrophobicContact CB-CD1 3.94Å; K105-L250 HydrophobicContact CB-CD2 3.62Å; K105-L250 HydrophobicContact CB-CG 4.43Å; K105-L250 HydrophobicContact CD-CD1 4.03Å; K105-L250 HydrophobicContact CD-CD2 4.37Å; K105-L250 HydrophobicContact CG-CD1 4.3Å; K105-N254 PolarHBondContact O-ND2 2.73Å; K105-R518 WeakPolarHBondContact CE-O 3.23Å; K105-R520 PolarHBondContact NZ-O 3.38Å
106S97.3Very high97.1Very high0 Ų032.2 Ų32.20%017%0.168CC..SBendtrans-146.4-179.4-176.677.40000112.4F102 V108 N254 T262F102-S106 CarbonylContact O-C 3.59Å; F102-S106 WeakPolarHBondContact O-CA 3.33Å; F102-S106 WeakPolarHBondContact O-CB 3.34Å; F102-S106 PolarHBondContact O-N 2.81Å; F102-S106 PolarHBondContact O-OG 2.93Å; S106-V108 VanDerWaalsContact C-N 3.34Å; S106-V108 WeakPolarHBondContact OG-CB 3.44Å; S106-V108 WeakPolarHBondContact OG-CG2 3.15Å; S106-V108 PolarHBondContact OG-N 3.02Å; S106-N254 WeakPolarHBondContact CA-OD1 3.29Å; S106-N254 WeakPolarHBondContact CB-OD1 3.49Å; S106-T262 WeakPolarHBondContact O-CA 3.37Å
107C97Very high96.9Very high22 Ų2235.1 Ų35.115%0.14919%0.192CC..SBendtrans-89.95.5169.273.20000113.9F77 C259 T261 H263F77-C107 WeakPolarHBondContact CD2-O 3.22Å; C107-C259 HydrophobicContact CB-CB 3.54Å; C107-C259 WeakPolarHBondContact CB-SG 3.43Å; C107-C259 PolarHBondContact N-SG 3.42Å; C107-C259 WeakPolarHBondContact SG-CA 3.31Å; C107-C259 WeakPolarHBondContact SG-CB 3.45Å; C107-C259 CovalentContact SG-SG 2.04Å; C107-C259 PolarHBondContact SG-SG 2.97Å; C107-T261 WeakPolarHBondContact CB-O 3.19Å; C107-H263 VanDerWaalsContact C-NE2 3.29Å; C107-H263 PolarHBondContact O-CD2 3.42Å; C107-H263 PolarHBondContact O-NE2 3.24Å
108V98.1Very high96.8Very high0 Ų033.8 Ų33.80%019%0.189CC..  trans-67.8132.7173.7-176.20000108.9F77 I79 F102 S106 F110 L161 L253 H263F77-V108 HydrophobicContact CE1-CB 4.49Å; F77-V108 HydrophobicContact CE1-CG1 4.06Å; F77-V108 HydrophobicContact CE1-CG2 4.31Å; F77-V108 HydrophobicContact CE2-CB 4.33Å; F77-V108 HydrophobicContact CE2-CG2 3.9Å; F77-V108 HydrophobicContact CZ-CB 4.15Å; F77-V108 HydrophobicContact CZ-CG1 4.18Å; F77-V108 HydrophobicContact CZ-CG2 3.61Å; I79-V108 HydrophobicContact CD1-CG1 4.31Å; F102-V108 HydrophobicContact CB-CB 4.18Å; F102-V108 HydrophobicContact CB-CG1 4.38Å; F102-V108 HydrophobicContact CD1-CB 3.97Å; F102-V108 HydrophobicContact CD1-CG1 4.1Å; F102-V108 HydrophobicContact CD1-CG2 4.13Å; F102-V108 HydrophobicContact CG-CB 4.42Å; F102-V108 HydrophobicContact CG-CG1 4.39Å; S106-V108 VanDerWaalsContact C-N 3.34Å; S106-V108 WeakPolarHBondContact OG-CB 3.44Å; S106-V108 WeakPolarHBondContact OG-CG2 3.15Å; S106-V108 PolarHBondContact OG-N 3.02Å; V108-F110 HydrophobicContact CG1-CE2 3.7Å; V108-F110 HydrophobicContact CG1-CZ 3.72Å; V108-L161 HydrophobicContact CG1-CD1 4.35Å; V108-L161 HydrophobicContact CG1-CD2 4.2Å; V108-L161 HydrophobicContact CG2-CD1 4.19Å; V108-L161 HydrophobicContact CG2-CD2 4.32Å; V108-L253 HydrophobicContact CG2-CD1 4.09Å; V108-L253 HydrophobicContact CG2-CD2 4.02Å; V108-L253 HydrophobicContact CG2-CG 4.28Å; V108-H263 PolarHBondContact O-CD2 2.86Å
109D97.6Very high96.7Very high36 Ų3636 Ų3619%0.19320%0.198CC..  trans-139.2160176.3-16717.4000110.4P78 I79 R103 H263P78-D109 CarbonylContact C-O 3.47Å; P78-D109 WeakPolarHBondContact CA-O 3.36Å; P78-D109 HydrophobicContact CB-CB 4.02Å; I79-D109 PolarHBondContact N-O 2.97Å; R103-D109 IonicContact CZ-OD1 2.63Å; R103-D109 IonicContact NE-OD1 2.8Å; R103-D109 PolarHBondContact NE-OD1 3.41Å; R103-D109 IonicContact NH2-OD1 2.82Å; R103-D109 PolarHBondContact NH2-OD1 2.79Å; R103-D109 VanDerWaalsContact NH2-OD1 3.16Å; D109-H263 WeakPolarHBondContact CB-NE2 3.25Å
110F98.2Very high96.7Very high4 Ų436.1 Ų36.12%0.01820%0.198CC..EExtended strand (participates in β ladder)trans-130.5142.4-174.7-61.4-89000109.3I79 Y81 F99 F102 R103 V108 I157I79-F110 HydrophobicContact CB-CD1 3.89Å; I79-F110 HydrophobicContact CB-CE1 4.12Å; I79-F110 HydrophobicContact CD1-CE1 3.9Å; I79-F110 HydrophobicContact CD1-CZ 4.37Å; I79-F110 HydrophobicContact CG1-CE1 4.42Å; I79-F110 HydrophobicContact CG2-CD1 4.37Å; I79-F110 HydrophobicContact CG2-CE1 4.46Å; I79-F110 CarbonylContact O-C 3.49Å; I79-F110 WeakPolarHBondContact O-CA 3.48Å; Y81-F110 HydrophobicContact CD1-CB 3.79Å; Y81-F110 HydrophobicContact CE1-CB 3.98Å; F99-F110 HydrophobicContact CB-CD2 3.79Å; F99-F110 HydrophobicContact CB-CE2 4.32Å; F99-F110 HydrophobicContact CB-CG 4.4Å; F99-F110 HydrophobicContact CD1-CB 4.44Å; F99-F110 AromaticContact CD1-CD1 3.94Å; F99-F110 HydrophobicContact CD1-CD1 3.94Å; F99-F110 AromaticContact CD1-CD2 3.49Å; F99-F110 HydrophobicContact CD1-CD2 3.49Å; F99-F110 VanDerWaalsContact CD1-CD2 3.49Å; F99-F110 HydrophobicContact CD1-CE1 4.04Å; F99-F110 AromaticContact CD1-CE2 3.61Å; F99-F110 HydrophobicContact CD1-CE2 3.61Å; F99-F110 AromaticContact CD1-CG 3.68Å; F99-F110 HydrophobicContact CD1-CG 3.68Å; F99-F110 AromaticContact CD1-CZ 3.89Å; F99-F110 HydrophobicContact CD1-CZ 3.89Å; F99-F110 HydrophobicContact CD2-CB 3.75Å; F99-F110 HydrophobicContact CD2-CD2 4.15Å; F99-F110 AromaticContact CD2-CG 3.9Å; F99-F110 HydrophobicContact CD2-CG 3.9Å; F99-F110 AromaticContact CE1-CD1 3.6Å; F99-F110 HydrophobicContact CE1-CD1 3.6Å; F99-F110 HydrophobicContact CE1-CD2 4.05Å; F99-F110 AromaticContact CE1-CE1 3.71Å; F99-F110 HydrophobicContact CE1-CE1 3.71Å; F99-F110 HydrophobicContact CE1-CE2 4.16Å; F99-F110 AromaticContact CE1-CG 3.79Å; F99-F110 HydrophobicContact CE1-CG 3.79Å; F99-F110 HydrophobicContact CE1-CZ 4.01Å; F99-F110 HydrophobicContact CE2-CB 3.86Å; F99-F110 HydrophobicContact CE2-CD1 4.26Å; F99-F110 HydrophobicContact CE2-CG 4.01Å; F99-F110 HydrophobicContact CG-CB 4.06Å; F99-F110 HydrophobicContact CG-CD1 4.41Å; F99-F110 AromaticContact CG-CD2 3.55Å; F99-F110 HydrophobicContact CG-CD2 3.55Å; F99-F110 HydrophobicContact CG-CE2 4.1Å; F99-F110 AromaticContact CG-CG 3.74Å; F99-F110 HydrophobicContact CG-CG 3.74Å; F99-F110 HydrophobicContact CZ-CB 4.24Å; F99-F110 AromaticContact CZ-CD1 3.77Å; F99-F110 HydrophobicContact CZ-CD1 3.77Å; F99-F110 HydrophobicContact CZ-CE1 4.3Å; F99-F110 AromaticContact CZ-CG 3.95Å; F99-F110 HydrophobicContact CZ-CG 3.95Å; F102-F110 HydrophobicContact CB-CE2 3.9Å; F102-F110 HydrophobicContact CD2-CE2 4.05Å; F102-F110 HydrophobicContact CD2-CZ 4.28Å; F102-F110 HydrophobicContact CG-CE2 4.04Å; F102-F110 HydrophobicContact CG-CZ 4.45Å; R103-F110 PolarHBondContact NH2-O 2.96Å; V108-F110 HydrophobicContact CG1-CE2 3.7Å; V108-F110 HydrophobicContact CG1-CZ 3.72Å; F110-I157 HydrophobicContact CE1-CG2 4.3Å; F110-I157 HydrophobicContact CZ-CD1 4.49Å; F110-I157 HydrophobicContact CZ-CG2 3.79Å
111K96.5Very high96.7Very high54 Ų5435.7 Ų35.724%0.23520%0.197CC..EExtended strand (participates in β ladder)trans-136.1152.3171.967.9162.6-168.4152.60111.3P78 I79 P80 Y81 E114 E116P78-K111 HydrophobicContact CB-CB 4.13Å; P78-K111 HydrophobicContact CB-CG 4Å; P78-K111 HydrophobicContact CG-CB 4.15Å; P78-K111 HydrophobicContact CG-CD 3.73Å; P78-K111 HydrophobicContact CG-CG 3.78Å; I79-K111 PolarHBondContact O-N 2.82Å; P80-K111 CarbonylContact C-O 3.46Å; P80-K111 VanDerWaalsContact CA-O 3.26Å; P80-K111 WeakPolarHBondContact CA-O 3.49Å; Y81-K111 WeakPolarHBondContact CD1-O 3.41Å; Y81-K111 WeakPolarHBondContact CE1-O 3.27Å; Y81-K111 PolarHBondContact N-O 3.41Å; K111-E114 IonicContact NZ-OE2 3.75Å; K111-E114 PolarHBondContact NZ-OE2 2.85Å; K111-E116 WeakPolarHBondContact CE-OE1 3.3Å; K111-E116 IonicContact NZ-OE1 3.6Å; K111-E116 PolarHBondContact NZ-OE1 3.3Å
112P96Very high96.7Very high49 Ų4934.4 Ų34.432%0.31819%0.19SC..EExtended strand (participates in β ladder)trans-51.6142.5168.1-29.938.2000112.1E603P112-E603 VanDerWaalsContact CB-OE2 3.25Å; P112-E603 WeakPolarHBondContact CB-OE2 3.47Å; P112-E603 WeakPolarHBondContact CG-OE2 3.4Å
113Y95.4Very high96.5Very high59 Ų5935.9 Ų35.923%0.23120%0.197CC..  trans-64.8131.6174.6175.6-100.1000112.3P80 Y81 I82 G115 E116 Y119 V604P80-Y113 HydrophobicContact CB-CD2 4.25Å; Y81-Y113 WeakPolarHBondContact O-CB 3.32Å; Y81-Y113 PolarHBondContact O-N 2.75Å; I82-Y113 HydrophobicContact CD1-CD1 3.79Å; I82-Y113 HydrophobicContact CD1-CE1 4.38Å; I82-Y113 HydrophobicContact CD1-CG 3.89Å; I82-Y113 VanDerWaalsContact CG1-CB 3.49Å; I82-Y113 HydrophobicContact CG1-CD1 4.2Å; I82-Y113 HydrophobicContact CG1-CG 3.91Å; Y113-G115 VanDerWaalsContact CZ-CA 3.46Å; Y113-G115 WeakPolarHBondContact OH-CA 3.06Å; Y113-E116 HydrophobicContact CD2-CB 4.49Å; Y113-E116 WeakPolarHBondContact CD2-OE2 3.42Å; Y113-E116 HydrophobicContact CE2-CB 4.26Å; Y113-E116 VanDerWaalsContact CE2-N 3.33Å; Y113-E116 WeakPolarHBondContact CE2-O 3.44Å; Y113-E116 PolarHBondContact OH-O 2.87Å; Y113-Y119 AromaticContact CD2-CD1 3.79Å; Y113-Y119 HydrophobicContact CD2-CD1 3.79Å; Y113-Y119 AromaticContact CD2-CD2 3.95Å; Y113-Y119 HydrophobicContact CD2-CD2 3.95Å; Y113-Y119 HydrophobicContact CD2-CE1 4.38Å; Y113-Y119 HydrophobicContact CD2-CE2 4.47Å; Y113-Y119 AromaticContact CD2-CG 3.56Å; Y113-Y119 HydrophobicContact CD2-CG 3.56Å; Y113-Y119 AromaticContact CE2-CD1 3.3Å; Y113-Y119 HydrophobicContact CE2-CD1 3.3Å; Y113-Y119 HydrophobicContact CE2-CD2 4.13Å; Y113-Y119 AromaticContact CE2-CE1 3.62Å; Y113-Y119 HydrophobicContact CE2-CE1 3.62Å; Y113-Y119 HydrophobicContact CE2-CE2 4.34Å; Y113-Y119 AromaticContact CE2-CG 3.61Å; Y113-Y119 HydrophobicContact CE2-CG 3.61Å; Y113-Y119 HydrophobicContact CG-CD2 4.5Å; Y113-V604 HydrophobicContact CD1-CG2 4.3Å
114E94.2Very high96.4Very high153 Ų15337.8 Ų37.872%0.71521%0.208SC*.SBendtrans-125.45.4-177.4-65.3176.3129.900113.1K111 E116K111-E114 IonicContact NZ-OE2 3.75Å; K111-E114 PolarHBondContact NZ-OE2 2.85Å; E114-E116 PolarHBondContact N-OE2 3.42Å
115G92.8Very high96.3Very high54 Ų5439.9 Ų39.956%0.55722%0.216SC*.SBendtrans123.915.2178.900000115Y113Y113-G115 VanDerWaalsContact CZ-CA 3.46Å; Y113-G115 WeakPolarHBondContact OH-CA 3.06Å
116E95.6Very high96.2Very high46 Ų4644.4 Ų44.422%0.21524%0.241CC..  trans-63.9153.2179-63.682.2-179.100112.4P80 K111 Y113 E114P80-E116 HydrophobicContact CB-CB 4.29Å; P80-E116 HydrophobicContact CB-CG 4.16Å; P80-E116 HydrophobicContact CG-CB 3.81Å; P80-E116 HydrophobicContact CG-CG 3.55Å; K111-E116 WeakPolarHBondContact CE-OE1 3.3Å; K111-E116 IonicContact NZ-OE1 3.6Å; K111-E116 PolarHBondContact NZ-OE1 3.3Å; Y113-E116 HydrophobicContact CD2-CB 4.49Å; Y113-E116 WeakPolarHBondContact CD2-OE2 3.42Å; Y113-E116 HydrophobicContact CE2-CB 4.26Å; Y113-E116 VanDerWaalsContact CE2-N 3.33Å; Y113-E116 WeakPolarHBondContact CE2-O 3.44Å; Y113-E116 PolarHBondContact OH-O 2.87Å; E114-E116 PolarHBondContact N-OE2 3.42Å
117S93.9Very high96.1Very high104 Ų10444.6 Ų44.673%0.72724%0.243SC*.SBendtrans-74.2-30.3177.157.40000112.9V137S117-V137 CarbonylContact O-C 3.5Å; S117-V137 WeakPolarHBondContact O-CA 3.46Å
118S95.9Very high96.2Very high13 Ų1343.5 Ų43.59%0.09124%0.236CC..SBendtrans-118.9134.7177.5-169.30000110.9W75 D134 V137W75-S118 WeakPolarHBondContact CH2-OG 3.22Å; W75-S118 WeakPolarHBondContact CZ3-OG 3.08Å; S118-D134 WeakPolarHBondContact CB-OD1 3.41Å; S118-D134 PolarHBondContact OG-OD1 2.9Å; S118-V137 PolarHBondContact OG-O 3.25Å
119Y97.4Very high96.2Very high47 Ų4744.2 Ų44.218%0.18424%0.238CC..EExtended strand (participates in β ladder)trans-167.5160.3-176.159.5-80.7000110.6P80 I82 Y113 I121 G138 Q139P80-Y119 CarbonylContact O-C 3.5Å; P80-Y119 VanDerWaalsContact O-CA 3.28Å; P80-Y119 WeakPolarHBondContact O-CA 3.4Å; P80-Y119 VanDerWaalsContact O-CB 3.31Å; P80-Y119 WeakPolarHBondContact O-CB 3.11Å; I82-Y119 HydrophobicContact CD1-CD2 3.87Å; I82-Y119 HydrophobicContact CD1-CE2 3.56Å; I82-Y119 HydrophobicContact CG1-CD2 4.13Å; I82-Y119 HydrophobicContact CG1-CE2 4.32Å; Y113-Y119 AromaticContact CD2-CD1 3.79Å; Y113-Y119 HydrophobicContact CD2-CD1 3.79Å; Y113-Y119 AromaticContact CD2-CD2 3.95Å; Y113-Y119 HydrophobicContact CD2-CD2 3.95Å; Y113-Y119 HydrophobicContact CD2-CE1 4.38Å; Y113-Y119 HydrophobicContact CD2-CE2 4.47Å; Y113-Y119 AromaticContact CD2-CG 3.56Å; Y113-Y119 HydrophobicContact CD2-CG 3.56Å; Y113-Y119 AromaticContact CE2-CD1 3.3Å; Y113-Y119 HydrophobicContact CE2-CD1 3.3Å; Y113-Y119 HydrophobicContact CE2-CD2 4.13Å; Y113-Y119 AromaticContact CE2-CE1 3.62Å; Y113-Y119 HydrophobicContact CE2-CE1 3.62Å; Y113-Y119 HydrophobicContact CE2-CE2 4.34Å; Y113-Y119 AromaticContact CE2-CG 3.61Å; Y113-Y119 HydrophobicContact CE2-CG 3.61Å; Y113-Y119 HydrophobicContact CG-CD2 4.5Å; Y119-I121 HydrophobicContact CD2-CD1 4.26Å; Y119-I121 HydrophobicContact CD2-CG1 3.59Å; Y119-I121 HydrophobicContact CE2-CD1 3.42Å; Y119-I121 VanDerWaalsContact CE2-CD1 3.42Å; Y119-I121 HydrophobicContact CE2-CG1 3.26Å; Y119-G138 WeakPolarHBondContact O-CA 3.36Å; Y119-Q139 PolarHBondContact O-N 2.87Å
120I98.2Very high96.2Very high1 Ų142.5 Ų42.51%0.00523%0.229CC..EExtended strand (participates in β ladder)trans-101.1128.5174.9-57.7178.2000109.6W75 I79 P80 Y81 I82 F122 Q139 L141 A160W75-I120 HydrophobicContact CH2-CG1 3.75Å; W75-I120 HydrophobicContact CZ2-CD1 3.97Å; W75-I120 HydrophobicContact CZ2-CG1 3.51Å; I79-I120 HydrophobicContact CG2-CD1 3.85Å; I79-I120 HydrophobicContact CG2-CG1 4.01Å; P80-I120 PolarHBondContact O-N 3.37Å; Y81-I120 CarbonylContact C-O 3.47Å; Y81-I120 WeakPolarHBondContact CA-O 3.43Å; I82-I120 PolarHBondContact N-O 3.1Å; I120-F122 HydrophobicContact CB-CE2 4.12Å; I120-F122 HydrophobicContact CG2-CD2 3.98Å; I120-F122 HydrophobicContact CG2-CE2 3.6Å; I120-F122 HydrophobicContact CG2-CZ 3.91Å; I120-Q139 HydrophobicContact CG1-CG 4.35Å; I120-L141 HydrophobicContact CG2-CB 3.75Å; I120-L141 HydrophobicContact CG2-CD1 4.16Å; I120-A160 HydrophobicContact CD1-CB 3.76Å
121I97.3Very high96Very high22 Ų2242.5 Ų42.511%0.11323%0.229CC..EExtended strand (participates in β ladder)trans-103.8111.1170.2-45.4179.3000108.4I82 A84 Y119 Q123 Q139 L141I82-I121 HydrophobicContact CB-CG1 4.46Å; I82-I121 HydrophobicContact CB-CG2 4.11Å; I82-I121 HydrophobicContact CD1-CG1 4.46Å; I82-I121 HydrophobicContact CG2-CG2 4.19Å; A84-I121 HydrophobicContact CB-CG2 4.3Å; Y119-I121 HydrophobicContact CD2-CD1 4.26Å; Y119-I121 HydrophobicContact CD2-CG1 3.59Å; Y119-I121 HydrophobicContact CE2-CD1 3.42Å; Y119-I121 VanDerWaalsContact CE2-CD1 3.42Å; Y119-I121 HydrophobicContact CE2-CG1 3.26Å; I121-Q123 HydrophobicContact CB-CG 4.23Å; I121-Q123 HydrophobicContact CG2-CG 3.47Å; I121-Q123 VanDerWaalsContact CG2-CG 3.47Å; I121-Q139 PolarHBondContact N-O 2.65Å; I121-L141 PolarHBondContact O-N 3.02Å
122F97.8Very high95.9Very high0 Ų040.3 Ų40.30%022%0.22CC..EExtended strand (participates in β ladder)trans-79.3123170.7-64.5-97.5000108.8I82 L83 A84 L87 I95 F99 I120 L141 I143 I157I82-F122 PolarHBondContact O-N 3.07Å; L83-F122 HydrophobicContact CD2-CB 3.94Å; L83-F122 HydrophobicContact CD2-CD2 4.03Å; L83-F122 HydrophobicContact CD2-CG 4.11Å; A84-F122 WeakPolarHBondContact CB-O 3.48Å; A84-F122 PolarHBondContact N-O 2.85Å; L87-F122 HydrophobicContact CD1-CB 3.75Å; L87-F122 WeakPolarHBondContact CD1-O 3.15Å; I95-F122 HydrophobicContact CD1-CB 3.8Å; I95-F122 HydrophobicContact CD1-CD1 3.73Å; I95-F122 HydrophobicContact CD1-CG 3.93Å; I95-F122 HydrophobicContact CG1-CD1 4.04Å; I95-F122 HydrophobicContact CG1-CE1 4.47Å; I95-F122 HydrophobicContact CG2-CD1 4.02Å; I95-F122 HydrophobicContact CG2-CD2 4.42Å; I95-F122 HydrophobicContact CG2-CE1 3.95Å; I95-F122 HydrophobicContact CG2-CE2 4.37Å; I95-F122 HydrophobicContact CG2-CG 4.26Å; I95-F122 HydrophobicContact CG2-CZ 4.14Å; F99-F122 HydrophobicContact CE1-CE2 4.13Å; F99-F122 AromaticContact CE1-CZ 3.75Å; F99-F122 HydrophobicContact CE1-CZ 3.75Å; F99-F122 AromaticContact CZ-CE2 3.69Å; F99-F122 HydrophobicContact CZ-CE2 3.69Å; F99-F122 AromaticContact CZ-CZ 3.8Å; F99-F122 HydrophobicContact CZ-CZ 3.8Å; I120-F122 HydrophobicContact CB-CE2 4.12Å; I120-F122 HydrophobicContact CG2-CD2 3.98Å; I120-F122 HydrophobicContact CG2-CE2 3.6Å; I120-F122 HydrophobicContact CG2-CZ 3.91Å; F122-L141 WeakPolarHBondContact CA-O 3.34Å; F122-L141 HydrophobicContact CD1-CB 4.4Å; F122-L141 HydrophobicContact CD1-CD1 4.34Å; F122-L141 HydrophobicContact CD1-CD2 3.78Å; F122-L141 HydrophobicContact CD1-CG 4.41Å; F122-L141 HydrophobicContact CE1-CD1 3.72Å; F122-L141 HydrophobicContact CE1-CD2 3.87Å; F122-L141 HydrophobicContact CE1-CG 4.26Å; F122-L141 HydrophobicContact CZ-CD1 4.17Å; F122-I143 HydrophobicContact CD1-CG1 4.15Å; F122-I157 HydrophobicContact CE1-CD1 4.17Å; F122-I157 HydrophobicContact CE1-CG1 4.07Å; F122-I157 HydrophobicContact CZ-CD1 4.13Å; F122-I157 HydrophobicContact CZ-CG1 4.09Å
123Q95.1Very high95.8Very high31 Ų3138 Ų3815%0.14521%0.205CC..EExtended strand (participates in β ladder)trans-139.4154.3-177.2-52.4-155.4-90.300111.6A84 I121 F125 N140 L141 S142 I143A84-Q123 HydrophobicContact CB-CB 4.32Å; A84-Q123 HydrophobicContact CB-CG 3.69Å; I121-Q123 HydrophobicContact CB-CG 4.23Å; I121-Q123 HydrophobicContact CG2-CG 3.47Å; I121-Q123 VanDerWaalsContact CG2-CG 3.47Å; Q123-F125 HydrophobicContact CB-CD2 3.97Å; Q123-F125 HydrophobicContact CB-CE2 3.61Å; Q123-F125 HydrophobicContact CB-CZ 4.09Å; Q123-F125 HydrophobicContact CG-CE2 4.09Å; Q123-F125 HydrophobicContact CG-CZ 4.42Å; Q123-F125 PolarHBondContact O-N 3.05Å; Q123-N140 PolarHBondContact OE1-OD1 3Å; Q123-N140 VanDerWaalsContact OE1-OD1 3.06Å; Q123-L141 PolarHBondContact N-O 3.46Å; Q123-S142 WeakPolarHBondContact O-CA 2.95Å; Q123-I143 PolarHBondContact O-N 3.47Å
124Q94.4Very high95.7Very high79 Ų7935.7 Ų35.737%0.36920%0.197SC..  trans-87.892.5170.9-167.8172.3-18.400110.2N86 L87N86-Q124 PolarHBondContact ND2-N 2.78Å; N86-Q124 PolarHBondContact ND2-O 2.99Å; N86-Q124 WeakPolarHBondContact O-CB 3.27Å; N86-Q124 PolarHBondContact O-OE1 3.24Å; L87-Q124 HydrophobicContact CD2-CB 4.25Å
125F96.1Very high95.6Very high58 Ų5830.3 Ų30.325%0.25417%0.172SC..  trans-98.5-173.4163.4-61-66000110.4Q123 W129 N140 S142 G144Q123-F125 HydrophobicContact CB-CD2 3.97Å; Q123-F125 HydrophobicContact CB-CE2 3.61Å; Q123-F125 HydrophobicContact CB-CZ 4.09Å; Q123-F125 HydrophobicContact CG-CE2 4.09Å; Q123-F125 HydrophobicContact CG-CZ 4.42Å; Q123-F125 PolarHBondContact O-N 3.05Å; F125-W129 HydrophobicContact CB-CZ2 4.06Å; F125-W129 AromaticContact CD2-CH2 3.97Å; F125-W129 HydrophobicContact CD2-CH2 3.97Å; F125-W129 AromaticContact CD2-CZ2 3.67Å; F125-W129 HydrophobicContact CD2-CZ2 3.67Å; F125-W129 HydrophobicContact CE2-CH2 4.34Å; F125-W129 HydrophobicContact CE2-CZ2 4.44Å; F125-W129 HydrophobicContact CG-CZ2 4.1Å; F125-N140 HydrophobicContact CE2-CB 4Å; F125-S142 WeakPolarHBondContact CB-OG 3.24Å; F125-S142 PolarHBondContact N-OG 3.08Å; F125-G144 WeakPolarHBondContact O-CA 3.25Å
126N95.5Very high95.6Very high100 Ų10032.7 Ų32.754%0.53517%0.168SC..SBendtrans-72.2137.3167.4-69.7-14.6000108.5A50 L52 W129A50-N126 HydrophobicContact CB-CB 4.19Å; L52-N126 WeakPolarHBondContact CD1-O 3.31Å; N126-W129 PolarHBondContact O-NE1 3.13Å
127G96Very high95.5Very high4 Ų433.8 Ų33.84%0.04118%0.178CC..SBendtrans75.8175.6177.800000115.7N47 S142 G144N47-G127 WeakPolarHBondContact OD1-CA 3.29Å; G127-S142 PolarHBondContact O-OG 3.45Å; G127-G144 WeakPolarHBondContact O-CA 3.46Å; G127-G144 PolarHBondContact O-N 3.15Å; G127-G144 VanDerWaalsContact O-N 3.11Å
128C97.9Very high95.5Very high0 Ų030.3 Ų30.30%016%0.158CC..EExtended strand (participates in β ladder)trans-108.4120.6170.9-28.40000106.9I43 N47 D58 S142 C147 I152 E156I43-C128 HydrophobicContact CG1-CB 4.37Å; I43-C128 HydrophobicContact CG2-CB 4.01Å; N47-C128 PolarHBondContact ND2-O 3.4Å; N47-C128 PolarHBondContact OD1-N 3.39Å; N47-C128 PolarHBondContact OD1-O 3.14Å; D58-C128 WeakPolarHBondContact CB-O 3.44Å; C128-S142 WeakPolarHBondContact CA-O 3.37Å; C128-C147 WeakPolarHBondContact CA-SG 3.26Å; C128-C147 HydrophobicContact CB-CB 3.74Å; C128-C147 WeakPolarHBondContact CB-SG 3.35Å; C128-C147 PolarHBondContact N-SG 2.88Å; C128-C147 WeakPolarHBondContact SG-CB 3.31Å; C128-C147 CovalentContact SG-SG 2.03Å; C128-C147 PolarHBondContact SG-SG 3.23Å; C128-I152 HydrophobicContact CB-CG2 3.91Å; C128-E156 HydrophobicContact CB-CG 4.41Å; C128-E156 WeakPolarHBondContact CB-OE1 3.45Å
129W98.3Very high95.4Very high14 Ų1429.8 Ų29.85%0.05315%0.154CC..EExtended strand (participates in β ladder)trans-164.5160-179.652.2-96.9000112.1L54 D58 L60 F125 N126 N140 S142 E156L54-W129 HydrophobicContact CD1-CB 3.51Å; L54-W129 HydrophobicContact CD1-CD2 4.5Å; L54-W129 HydrophobicContact CD1-CG 3.63Å; D58-W129 HydrophobicContact CB-CB 4.31Å; D58-W129 WeakPolarHBondContact O-CA 3.23Å; D58-W129 WeakPolarHBondContact O-CB 3.28Å; L60-W129 HydrophobicContact CB-CE3 3.92Å; L60-W129 HydrophobicContact CB-CZ3 4.22Å; L60-W129 HydrophobicContact CD2-CE3 4.03Å; L60-W129 HydrophobicContact CD2-CH2 3.99Å; L60-W129 HydrophobicContact CD2-CZ3 3.47Å; L60-W129 VanDerWaalsContact CD2-CZ3 3.47Å; L60-W129 HydrophobicContact CG-CZ3 4.43Å; F125-W129 HydrophobicContact CB-CZ2 4.06Å; F125-W129 AromaticContact CD2-CH2 3.97Å; F125-W129 HydrophobicContact CD2-CH2 3.97Å; F125-W129 AromaticContact CD2-CZ2 3.67Å; F125-W129 HydrophobicContact CD2-CZ2 3.67Å; F125-W129 HydrophobicContact CE2-CH2 4.34Å; F125-W129 HydrophobicContact CE2-CZ2 4.44Å; F125-W129 HydrophobicContact CG-CZ2 4.1Å; N126-W129 PolarHBondContact O-NE1 3.13Å; W129-N140 HydrophobicContact CH2-CB 4.08Å; W129-N140 HydrophobicContact CZ3-CB 4.22Å; W129-S142 PolarHBondContact N-O 3.01Å; W129-S142 VanDerWaalsContact NE1-CB 3.3Å; W129-S142 PolarHBondContact O-N 2.88Å; W129-E156 WeakPolarHBondContact CA-OE2 3.19Å; W129-E156 PolarHBondContact N-OE1 3.09Å; W129-E156 PolarHBondContact N-OE2 2.88Å
130S97.8Very high95.3Very high0 Ų029.8 Ų29.80%016%0.158CC..BIsolated β-bridgetrans-147.7164.4-178.7-165.80000111.4D58 I59 L60 E156D58-S130 PolarHBondContact O-N 2.73Å; D58-S130 VanDerWaalsContact O-N 3.11Å; I59-S130 WeakPolarHBondContact CA-O 3.38Å; L60-S130 PolarHBondContact N-O 2.65Å; S130-E156 WeakPolarHBondContact CB-O 3.32Å; S130-E156 WeakPolarHBondContact CB-OE2 3.43Å; S130-E156 PolarHBondContact N-OE2 3.39Å; S130-E156 VanDerWaalsContact N-OE2 3.07Å; S130-E156 PolarHBondContact OG-O 2.92Å
131E94.9Very high95.4Very high5 Ų529.8 Ų29.82%0.02316%0.157CC..  trans-88.8156.6166.9-66.9175-178.400109.5L60 Q62 Q135 Q139 H159 A160L60-E131 HydrophobicContact CB-CG 4.01Å; L60-E131 HydrophobicContact CD2-CG 4.18Å; L60-E131 HydrophobicContact CG-CG 4.31Å; Q62-E131 VanDerWaalsContact CD-OE1 3.29Å; Q62-E131 WeakPolarHBondContact CG-OE1 3.44Å; Q62-E131 PolarHBondContact NE2-OE1 3.36Å; E131-Q135 HydrophobicContact CB-CG 4.34Å; E131-Q135 WeakPolarHBondContact OE2-CG 3.49Å; E131-Q139 VanDerWaalsContact OE2-CB 3.29Å; E131-Q139 WeakPolarHBondContact OE2-CB 3Å; E131-H159 CarbonylContact O-C 3.6Å; E131-H159 VanDerWaalsContact O-C 3.31Å; E131-A160 VanDerWaalsContact O-CA 3.28Å; E131-A160 WeakPolarHBondContact O-CA 3.46Å; E131-A160 PolarHBondContact O-N 2.78Å
132V93.9Very high95.4Very high7 Ų728.7 Ų28.74%0.04215%0.152CC..SBendtrans-94.9114.2-179.8-177.80000111.6I59 N66 Q135 H159 Y164I59-V132 HydrophobicContact CB-CG2 4.49Å; I59-V132 HydrophobicContact CD1-CG2 4.05Å; I59-V132 HydrophobicContact CG1-CG2 4.15Å; I59-V132 HydrophobicContact CG2-CG2 3.58Å; N66-V132 VanDerWaalsContact O-CG1 3.27Å; N66-V132 WeakPolarHBondContact O-CG1 3.49Å; V132-Q135 PolarHBondContact O-NE2 2.86Å; V132-H159 VanDerWaalsContact CA-O 3.26Å; V132-H159 WeakPolarHBondContact CA-O 3.26Å; V132-H159 HydrophobicContact CG2-CB 4.42Å; V132-Y164 HydrophobicContact CB-CE1 4.35Å; V132-Y164 HydrophobicContact CG1-CD2 4.26Å; V132-Y164 HydrophobicContact CG1-CE1 4.36Å; V132-Y164 HydrophobicContact CG1-CE2 3.83Å; V132-Y164 HydrophobicContact CG2-CD1 4.26Å; V132-Y164 HydrophobicContact CG2-CE1 3.79Å
133G93.6Very high95.4Very high0 Ų028.8 Ų28.80%015%0.152CC..SBendtrans81.9177.5-178.400000114.8T73 Q135 Q139 H159 A160T73-G133 CarbonylContact O-C 3.58Å; T73-G133 WeakPolarHBondContact O-CA 3.34Å; G133-Q135 PolarHBondContact O-N 2.8Å; G133-Q135 PolarHBondContact O-NE2 3.45Å; G133-Q139 PolarHBondContact O-NE2 2.91Å; G133-Q139 PolarHBondContact O-OE1 2.75Å; G133-H159 PolarHBondContact N-O 2.97Å; G133-H159 VanDerWaalsContact N-O 3.13Å; G133-A160 CarbonylContact C-O 3.5Å; G133-A160 VanDerWaalsContact C-O 3.23Å; G133-A160 WeakPolarHBondContact CA-O 3.21Å; G133-A160 PolarHBondContact N-O 2.78Å
134D94Very high95.4Very high12 Ų1227.4 Ų27.46%0.06415%0.147CC..  trans-74113.2173.4179.65.5000110.2T73 W75 S118 H136T73-D134 PolarHBondContact O-N 3.11Å; W75-D134 HydrophobicContact CD2-CB 3.73Å; W75-D134 HydrophobicContact CE3-CB 4.25Å; W75-D134 HydrophobicContact CG-CB 3.92Å; W75-D134 HydrophobicContact CZ2-CB 4.2Å; S118-D134 WeakPolarHBondContact CB-OD1 3.41Å; S118-D134 PolarHBondContact OG-OD1 2.9Å; D134-H136 PolarHBondContact O-N 2.93Å; D134-H136 VanDerWaalsContact OD1-CA 3.28Å; D134-H136 WeakPolarHBondContact OD1-CA 2.82Å; D134-H136 PolarHBondContact OD1-N 2.85Å; D134-H136 IonicContact OD1-ND1 3.7Å; D134-H136 PolarHBondContact OD1-ND1 3.29Å; D134-H136 IonicContact OD2-CE1 3.15Å; D134-H136 IonicContact OD2-ND1 2.74Å; D134-H136 PolarHBondContact OD2-ND1 2.81Å; D134-H136 VanDerWaalsContact OD2-ND1 3.09Å
135Q91.6Very high95.3Very high40 Ų4031.8 Ų31.819%0.18717%0.167CC..  trans-83.14.1175.8-57.1-42.1-66.200113.8N66 E131 V132 G133 V137N66-Q135 PolarHBondContact ND2-OE1 3.01Å; E131-Q135 HydrophobicContact CB-CG 4.34Å; E131-Q135 WeakPolarHBondContact OE2-CG 3.49Å; V132-Q135 PolarHBondContact O-NE2 2.86Å; G133-Q135 PolarHBondContact O-N 2.8Å; G133-Q135 PolarHBondContact O-NE2 3.45Å; Q135-V137 HydrophobicContact CB-CG2 3.92Å; Q135-V137 PolarHBondContact O-N 3.13Å
136H92.5Very high95Very high103 Ų10330.2 Ų30.248%0.47717%0.168SC..SBendtrans60.821-177.4-55.5-44.6000115N72 D134N72-H136 PolarHBondContact O-CE1 2.98Å; N72-H136 PolarHBondContact O-NE2 3.14Å; D134-H136 PolarHBondContact O-N 2.93Å; D134-H136 VanDerWaalsContact OD1-CA 3.28Å; D134-H136 WeakPolarHBondContact OD1-CA 2.82Å; D134-H136 PolarHBondContact OD1-N 2.85Å; D134-H136 IonicContact OD1-ND1 3.7Å; D134-H136 PolarHBondContact OD1-ND1 3.29Å; D134-H136 IonicContact OD2-CE1 3.15Å; D134-H136 IonicContact OD2-ND1 2.74Å; D134-H136 PolarHBondContact OD2-ND1 2.81Å; D134-H136 VanDerWaalsContact OD2-ND1 3.09Å
137V92.7Very high95Very high70 Ų7025.5 Ų25.542%0.42414%0.142SC..SBendtrans-137.7173.1177.1-63.50000109.3S117 S118 Q135 Q139S117-V137 CarbonylContact O-C 3.5Å; S117-V137 WeakPolarHBondContact O-CA 3.46Å; S118-V137 PolarHBondContact OG-O 3.25Å; Q135-V137 HydrophobicContact CB-CG2 3.92Å; Q135-V137 PolarHBondContact O-N 3.13Å; V137-Q139 PolarHBondContact O-N 3.25Å; V137-Q139 VanDerWaalsContact O-N 3.16Å
138G93.8Very high95Very high30 Ų3027.4 Ų27.431%0.30915%0.151SC..EExtended strand (participates in β ladder)trans-65.4112.4165.200000110Y119Y119-G138 WeakPolarHBondContact O-CA 3.36Å
139Q94.9Very high94.8Very high3 Ų329 Ų291%0.01416%0.158CC..EExtended strand (participates in β ladder)trans-109.7145.7179.567.6-169.26500111.8W75 Y119 I120 I121 E131 G133 V137W75-Q139 HydrophobicContact CH2-CG 4.46Å; W75-Q139 HydrophobicContact CZ2-CG 4.1Å; Y119-Q139 PolarHBondContact O-N 2.87Å; I120-Q139 HydrophobicContact CG1-CG 4.35Å; I121-Q139 PolarHBondContact N-O 2.65Å; E131-Q139 VanDerWaalsContact OE2-CB 3.29Å; E131-Q139 WeakPolarHBondContact OE2-CB 3Å; G133-Q139 PolarHBondContact O-NE2 2.91Å; G133-Q139 PolarHBondContact O-OE1 2.75Å; V137-Q139 PolarHBondContact O-N 3.25Å; V137-Q139 VanDerWaalsContact O-N 3.16Å
140N96.1Very high94.8Very high47 Ų4728.5 Ų28.525%0.25116%0.156SC..EExtended strand (participates in β ladder)trans-89.2141.3-179.2-68.5-35.7000110.7Q123 F125 W129Q123-N140 PolarHBondContact OE1-OD1 3Å; Q123-N140 VanDerWaalsContact OE1-OD1 3.06Å; F125-N140 HydrophobicContact CE2-CB 4Å; W129-N140 HydrophobicContact CH2-CB 4.08Å; W129-N140 HydrophobicContact CZ3-CB 4.22Å
141L98.3Very high94.7Very high0 Ų028.7 Ų28.70%016%0.158CC..EExtended strand (participates in β ladder)trans-125.2119.6167.3-170.3163.7000107.6I120 I121 F122 Q123 I143 E156 I157 A160I120-L141 HydrophobicContact CG2-CB 3.75Å; I120-L141 HydrophobicContact CG2-CD1 4.16Å; I121-L141 PolarHBondContact O-N 3.02Å; F122-L141 WeakPolarHBondContact CA-O 3.34Å; F122-L141 HydrophobicContact CD1-CB 4.4Å; F122-L141 HydrophobicContact CD1-CD1 4.34Å; F122-L141 HydrophobicContact CD1-CD2 3.78Å; F122-L141 HydrophobicContact CD1-CG 4.41Å; F122-L141 HydrophobicContact CE1-CD1 3.72Å; F122-L141 HydrophobicContact CE1-CD2 3.87Å; F122-L141 HydrophobicContact CE1-CG 4.26Å; F122-L141 HydrophobicContact CZ-CD1 4.17Å; Q123-L141 PolarHBondContact N-O 3.46Å; L141-I143 HydrophobicContact CD2-CD1 3.43Å; L141-I143 VanDerWaalsContact CD2-CD1 3.43Å; L141-I143 HydrophobicContact CD2-CG1 3.76Å; L141-E156 HydrophobicContact CD1-CB 4.03Å; L141-E156 HydrophobicContact CD2-CB 3.74Å; L141-E156 HydrophobicContact CD2-CG 4.35Å; L141-E156 HydrophobicContact CG-CB 4.02Å; L141-I157 HydrophobicContact CD1-CG1 4.13Å; L141-A160 HydrophobicContact CD1-CB 4.42Å
142S98.4Very high94.9Very high0 Ų028.5 Ų28.50%016%0.157CC..EExtended strand (participates in β ladder)trans-86.1118-177.2-175.40000111.1Q123 F125 G127 C128 W129Q123-S142 WeakPolarHBondContact O-CA 2.95Å; F125-S142 WeakPolarHBondContact CB-OG 3.24Å; F125-S142 PolarHBondContact N-OG 3.08Å; G127-S142 PolarHBondContact O-OG 3.45Å; C128-S142 WeakPolarHBondContact CA-O 3.37Å; W129-S142 PolarHBondContact N-O 3.01Å; W129-S142 VanDerWaalsContact NE1-CB 3.3Å; W129-S142 PolarHBondContact O-N 2.88Å
143I97.9Very high95.1Very high1 Ų128.1 Ų28.11%0.00515%0.154CC..EExtended strand (participates in β ladder)trans-109.582.1162.8-56.1-57.2000106.7L87 A91 I95 F122 Q123 L141 C147 D148 I153 E156L87-I143 HydrophobicContact CD2-CB 4.11Å; A91-I143 HydrophobicContact CB-CG2 4.06Å; I95-I143 HydrophobicContact CD1-CG1 4.1Å; I95-I143 HydrophobicContact CG1-CG1 4.35Å; F122-I143 HydrophobicContact CD1-CG1 4.15Å; Q123-I143 PolarHBondContact O-N 3.47Å; L141-I143 HydrophobicContact CD2-CD1 3.43Å; L141-I143 VanDerWaalsContact CD2-CD1 3.43Å; L141-I143 HydrophobicContact CD2-CG1 3.76Å; I143-C147 HydrophobicContact CG2-CB 3.93Å; I143-D148 HydrophobicContact CG2-CB 4.35Å; I143-I153 HydrophobicContact CD1-CB 4.42Å; I143-I153 HydrophobicContact CD1-CG1 3.8Å; I143-I153 HydrophobicContact CG1-CG1 4.4Å; I143-I153 HydrophobicContact CG2-CG1 4.44Å; I143-E156 HydrophobicContact CD1-CG 4.39Å
144G95Very high95.3Very high3 Ų328.1 Ų28.13%0.03115%0.154CC..  trans-73-174.2179.600000114F125 G127 G146 C147F125-G144 WeakPolarHBondContact O-CA 3.25Å; G127-G144 WeakPolarHBondContact O-CA 3.46Å; G127-G144 PolarHBondContact O-N 3.15Å; G127-G144 VanDerWaalsContact O-N 3.11Å; G144-G146 PolarHBondContact O-N 2.85Å; G144-C147 PolarHBondContact N-SG 3.34Å; G144-C147 VanDerWaalsContact N-SG 3.41Å; G144-C147 WeakPolarHBondContact O-CB 3.13Å; G144-C147 PolarHBondContact O-N 3.48Å; G144-C147 VanDerWaalsContact O-N 3.12Å
145Q91.6Very high95.6Very high170 Ų17027.6 Ų27.679%0.79415%0.152SC*.THydrogen-bonded Turntrans-63124.3173.9-177.9176.3100110.3
146G90.9Very high95.9Very high26 Ų2625.7 Ų25.727%0.26814%0.143SC..THydrogen-bonded Turntrans88.20.8-177.600000114.5I46 G144 Y149I46-G146 VanDerWaalsContact CD1-O 3.3Å; I46-G146 WeakPolarHBondContact CD1-O 3.47Å; G144-G146 PolarHBondContact O-N 2.85Å; G146-Y149 VanDerWaalsContact O-CD2 3.29Å; G146-Y149 WeakPolarHBondContact O-CD2 3.35Å; G146-Y149 WeakPolarHBondContact O-CE2 3.13Å
147C95.9Very high96.2Very high0 Ų020.8 Ų20.80%012%0.12CC..  trans-97.5-4.7-179.9-530000113.4C128 I143 G144 Y149 I152C128-C147 WeakPolarHBondContact CA-SG 3.26Å; C128-C147 HydrophobicContact CB-CB 3.74Å; C128-C147 WeakPolarHBondContact CB-SG 3.35Å; C128-C147 PolarHBondContact N-SG 2.88Å; C128-C147 WeakPolarHBondContact SG-CB 3.31Å; C128-C147 CovalentContact SG-SG 2.03Å; C128-C147 PolarHBondContact SG-SG 3.23Å; I143-C147 HydrophobicContact CG2-CB 3.93Å; G144-C147 PolarHBondContact N-SG 3.34Å; G144-C147 VanDerWaalsContact N-SG 3.41Å; G144-C147 WeakPolarHBondContact O-CB 3.13Å; G144-C147 PolarHBondContact O-N 3.48Å; G144-C147 VanDerWaalsContact O-N 3.12Å; C147-Y149 PolarHBondContact O-N 2.9Å; C147-I152 HydrophobicContact CB-CG2 4.09Å
148D94.9Very high96.5Very high44 Ų4417.5 Ų17.524%0.23510%0.1CC..  trans-79.730.5-173.157.4-37.3000114.1N90 A91 A94 I143N90-D148 PolarHBondContact ND2-OD2 3.3Å; A91-D148 HydrophobicContact CB-CB 3.85Å; A94-D148 WeakPolarHBondContact CB-O 3.26Å; I143-D148 HydrophobicContact CG2-CB 4.35Å
149Y94.8Very high96.7Very high34 Ų3416 Ų1613%0.1339%0.085CC..SBendtrans-96.1138.5171.9-64.4-90000110.1Q40 G146 C147 A151 I152 I153 M525Q40-Y149 HydrophobicContact CB-CE1 4.32Å; Q40-Y149 HydrophobicContact CG-CD1 4.19Å; Q40-Y149 HydrophobicContact CG-CD2 4.18Å; Q40-Y149 HydrophobicContact CG-CE1 3.92Å; Q40-Y149 HydrophobicContact CG-CE2 3.91Å; Q40-Y149 HydrophobicContact CG-CG 4.32Å; G146-Y149 VanDerWaalsContact O-CD2 3.29Å; G146-Y149 WeakPolarHBondContact O-CD2 3.35Å; G146-Y149 WeakPolarHBondContact O-CE2 3.13Å; C147-Y149 PolarHBondContact O-N 2.9Å; Y149-A151 VanDerWaalsContact C-N 3.34Å; Y149-A151 PolarHBondContact O-N 3.29Å; Y149-I152 HydrophobicContact CD2-CD1 4.06Å; Y149-I152 PolarHBondContact O-N 3.01Å; Y149-I153 WeakPolarHBondContact O-CG1 3.33Å; Y149-I153 PolarHBondContact O-N 3.15Å; Y149-M525 HydrophobicContact CD1-SD 3.87Å; Y149-M525 HydrophobicContact CE1-SD 3.87Å
150K96.6Very high96.8Very high4 Ų415.9 Ų15.92%0.0178%0.084CC..Hα-helixtrans-46.8-53.5-178.2-176.4-167.772.5780112.5Y97 M101 I152 I153 E154 L243 D244Y97-K150 HydrophobicContact CD1-CB 4.24Å; Y97-K150 HydrophobicContact CD1-CD 3.94Å; Y97-K150 HydrophobicContact CD1-CG 4.04Å; Y97-K150 HydrophobicContact CE1-CB 4.3Å; Y97-K150 HydrophobicContact CE1-CD 3.47Å; Y97-K150 VanDerWaalsContact CE1-CD 3.47Å; Y97-K150 HydrophobicContact CE1-CG 4.07Å; M101-K150 HydrophobicContact CG-CD 3.97Å; K150-I152 VanDerWaalsContact C-N 3.34Å; K150-I152 PolarHBondContact O-N 3.29Å; K150-I153 PolarHBondContact O-N 2.83Å; K150-E154 HydrophobicContact CG-CG 4.42Å; K150-E154 WeakPolarHBondContact CG-OE1 3.3Å; K150-E154 VanDerWaalsContact NZ-CD 3.26Å; K150-E154 IonicContact NZ-OE1 3.47Å; K150-E154 PolarHBondContact NZ-OE1 2.02Å; K150-E154 IonicContact NZ-OE2 2.87Å; K150-E154 PolarHBondContact NZ-OE2 3.32Å; K150-E154 WeakPolarHBondContact O-CB 3.33Å; K150-E154 VanDerWaalsContact O-CG 3.3Å; K150-E154 WeakPolarHBondContact O-CG 3.27Å; K150-E154 PolarHBondContact O-N 3.11Å; K150-L243 VanDerWaalsContact CE-O 3.26Å; K150-L243 WeakPolarHBondContact CE-O 3.36Å; K150-L243 PolarHBondContact NZ-O 2.84Å; K150-D244 IonicContact NZ-OD1 2.85Å; K150-D244 IonicContact NZ-OD2 3.61Å; K150-D244 PolarHBondContact NZ-OD2 3.26Å
151A96.7Very high96.8Very high4 Ų413.7 Ų13.73%0.0337%0.073CC..Hα-helixtrans-64.7-32.9-177.400000113.8Y149 H155 L211 R242Y149-A151 VanDerWaalsContact C-N 3.34Å; Y149-A151 PolarHBondContact O-N 3.29Å; A151-H155 WeakPolarHBondContact O-CB 3.37Å; A151-H155 PolarHBondContact O-N 2.92Å; A151-L211 HydrophobicContact CB-CD1 3.86Å; A151-R242 HydrophobicContact CB-CB 4.05Å; A151-R242 WeakPolarHBondContact CB-O 3.46Å
152I97.9Very high96.5Very high0 Ų013.9 Ų13.90%07%0.074CC..Hα-helixtrans-69.8-44.1175.1-66.8179.2000109.6I43 I46 C128 C147 Y149 K150 E154 H155 E156I43-I152 HydrophobicContact CD1-CB 4.44Å; I43-I152 HydrophobicContact CD1-CG1 4.3Å; I43-I152 HydrophobicContact CD1-CG2 3.97Å; I43-I152 HydrophobicContact CG1-CB 4.4Å; I43-I152 HydrophobicContact CG1-CD1 4.2Å; I43-I152 HydrophobicContact CG1-CG1 3.97Å; I43-I152 HydrophobicContact CG1-CG2 3.81Å; I46-I152 HydrophobicContact CD1-CD1 4.32Å; C128-I152 HydrophobicContact CB-CG2 3.91Å; C147-I152 HydrophobicContact CB-CG2 4.09Å; Y149-I152 HydrophobicContact CD2-CD1 4.06Å; Y149-I152 PolarHBondContact O-N 3.01Å; K150-I152 VanDerWaalsContact C-N 3.34Å; K150-I152 PolarHBondContact O-N 3.29Å; I152-E154 VanDerWaalsContact C-N 3.33Å; I152-E154 PolarHBondContact O-N 3.47Å; I152-H155 WeakPolarHBondContact O-CB 3.3Å; I152-H155 PolarHBondContact O-N 2.83Å; I152-E156 WeakPolarHBondContact O-CG 3.43Å; I152-E156 PolarHBondContact O-N 2.88Å
153I98.7Very high96.3Very high0 Ų014.1 Ų14.10%08%0.075CC..Hα-helixtrans-63.1-42.4177.4-61.9159000110.9A94 I95 A98 I143 Y149 K150 H155 E156 I157A94-I153 HydrophobicContact CB-CD1 3.61Å; I95-I153 HydrophobicContact CB-CG2 4.46Å; I95-I153 HydrophobicContact CG1-CD1 3.99Å; I95-I153 HydrophobicContact CG1-CG1 4.34Å; I95-I153 HydrophobicContact CG1-CG2 4Å; A98-I153 HydrophobicContact CB-CB 4.17Å; A98-I153 HydrophobicContact CB-CG2 3.75Å; I143-I153 HydrophobicContact CD1-CB 4.42Å; I143-I153 HydrophobicContact CD1-CG1 3.8Å; I143-I153 HydrophobicContact CG1-CG1 4.4Å; I143-I153 HydrophobicContact CG2-CG1 4.44Å; Y149-I153 WeakPolarHBondContact O-CG1 3.33Å; Y149-I153 PolarHBondContact O-N 3.15Å; K150-I153 PolarHBondContact O-N 2.83Å; I153-H155 VanDerWaalsContact C-N 3.31Å; I153-H155 PolarHBondContact O-N 3.01Å; I153-E156 PolarHBondContact O-N 2.78Å; I153-I157 HydrophobicContact CG2-CD1 3.74Å; I153-I157 HydrophobicContact CG2-CG1 4.41Å; I153-I157 WeakPolarHBondContact O-CB 3.48Å; I153-I157 VanDerWaalsContact O-CG1 3.23Å; I153-I157 WeakPolarHBondContact O-CG1 3.45Å; I153-I157 PolarHBondContact O-N 2.95Å
154E98.8Very high96.2Very high0 Ų014.7 Ų14.70%08%0.077CC..Hα-helixtrans-58-42.5174.1-74.6169.6170.600111.9A98 M101 F102 K150 I152 I157 L158 L211 F245A98-E154 HydrophobicContact CB-CG 4.04Å; M101-E154 VanDerWaalsContact CB-OE1 3.27Å; M101-E154 WeakPolarHBondContact CB-OE1 2.98Å; M101-E154 VanDerWaalsContact CG-OE1 3.23Å; M101-E154 WeakPolarHBondContact CG-OE1 3.43Å; F102-E154 HydrophobicContact CE2-CG 4.32Å; K150-E154 HydrophobicContact CG-CG 4.42Å; K150-E154 WeakPolarHBondContact CG-OE1 3.3Å; K150-E154 VanDerWaalsContact NZ-CD 3.26Å; K150-E154 IonicContact NZ-OE1 3.47Å; K150-E154 PolarHBondContact NZ-OE1 2.02Å; K150-E154 IonicContact NZ-OE2 2.87Å; K150-E154 PolarHBondContact NZ-OE2 3.32Å; K150-E154 WeakPolarHBondContact O-CB 3.33Å; K150-E154 VanDerWaalsContact O-CG 3.3Å; K150-E154 WeakPolarHBondContact O-CG 3.27Å; K150-E154 PolarHBondContact O-N 3.11Å; I152-E154 VanDerWaalsContact C-N 3.33Å; I152-E154 PolarHBondContact O-N 3.47Å; E154-I157 PolarHBondContact O-N 2.86Å; E154-L158 WeakPolarHBondContact O-CG 2.89Å; E154-L158 PolarHBondContact O-N 3.38Å; E154-L211 HydrophobicContact CB-CD2 3.6Å; E154-F245 HydrophobicContact CB-CE1 3.73Å; E154-F245 HydrophobicContact CB-CE2 4.45Å; E154-F245 HydrophobicContact CB-CZ 3.62Å; E154-F245 HydrophobicContact CG-CE1 4.17Å; E154-F245 HydrophobicContact CG-CE2 3.99Å; E154-F245 HydrophobicContact CG-CZ 3.52Å
155H98.8Very high96.3Very high1 Ų114.6 Ų14.61%0.0058%0.076CC..Hα-helixtrans-61.1-50.3175.9-179.6106.9000112.2I43 D58 A151 I152 I153 I157 L158 H159 H165 L211 M212I43-H155 HydrophobicContact CD1-CB 4.1Å; I43-H155 VanDerWaalsContact CD1-CD2 3.41Å; I43-H155 WeakPolarHBondContact CD1-CD2 3.44Å; D58-H155 IonicContact OD2-CD2 3.84Å; D58-H155 IonicContact OD2-NE2 2.88Å; D58-H155 PolarHBondContact OD2-NE2 2.81Å; A151-H155 WeakPolarHBondContact O-CB 3.37Å; A151-H155 PolarHBondContact O-N 2.92Å; I152-H155 WeakPolarHBondContact O-CB 3.3Å; I152-H155 PolarHBondContact O-N 2.83Å; I153-H155 VanDerWaalsContact C-N 3.31Å; I153-H155 PolarHBondContact O-N 3.01Å; H155-I157 VanDerWaalsContact C-N 3.27Å; H155-I157 PolarHBondContact O-N 3.02Å; H155-L158 WeakPolarHBondContact O-CB 3.38Å; H155-L158 PolarHBondContact O-N 2.94Å; H155-H159 AromaticContact CD2-CD2 3.66Å; H155-H159 AromaticContact CD2-NE2 3.59Å; H155-H159 AromaticContact CE1-NE2 3.99Å; H155-H159 AromaticContact NE2-CD2 3.65Å; H155-H159 AromaticContact NE2-CE1 3.99Å; H155-H159 AromaticContact NE2-NE2 3.05Å; H155-H159 PolarHBondContact NE2-NE2 2.82Å; H155-H159 PolarHBondContact O-N 2.89Å; H155-H165 AromaticContact CE1-CD2 3.72Å; H155-H165 AromaticContact CE1-NE2 3.59Å; H155-H165 AromaticContact NE2-NE2 3.49Å; H155-H165 PolarHBondContact NE2-NE2 2.75Å; H155-L211 HydrophobicContact CB-CD2 4.28Å; H155-L211 HydrophobicContact CB-CG 4.18Å; H155-L211 PolarHBondContact ND1-O 3.42Å; H155-M212 HydrophobicContact CB-SD 4.38Å; H155-M212 PolarHBondContact ND1-SD 3.39Å
156E98.8Very high96.6Very high0 Ų06.7 Ų6.70%04%0.039CC..Hα-helixtrans-64.6-32.1179-62.3-55.1162.300112.8C128 W129 S130 L141 I143 I152 I153 H159 A160C128-E156 HydrophobicContact CB-CG 4.41Å; C128-E156 WeakPolarHBondContact CB-OE1 3.45Å; W129-E156 WeakPolarHBondContact CA-OE2 3.19Å; W129-E156 PolarHBondContact N-OE1 3.09Å; W129-E156 PolarHBondContact N-OE2 2.88Å; S130-E156 WeakPolarHBondContact CB-O 3.32Å; S130-E156 WeakPolarHBondContact CB-OE2 3.43Å; S130-E156 PolarHBondContact N-OE2 3.39Å; S130-E156 VanDerWaalsContact N-OE2 3.07Å; S130-E156 PolarHBondContact OG-O 2.92Å; L141-E156 HydrophobicContact CD1-CB 4.03Å; L141-E156 HydrophobicContact CD2-CB 3.74Å; L141-E156 HydrophobicContact CD2-CG 4.35Å; L141-E156 HydrophobicContact CG-CB 4.02Å; I143-E156 HydrophobicContact CD1-CG 4.39Å; I152-E156 WeakPolarHBondContact O-CG 3.43Å; I152-E156 PolarHBondContact O-N 2.88Å; I153-E156 PolarHBondContact O-N 2.78Å; E156-H159 WeakPolarHBondContact O-CB 3.25Å; E156-H159 PolarHBondContact O-N 2.94Å; E156-H159 IonicContact OE2-CD2 2.85Å; E156-A160 PolarHBondContact O-N 3.08Å; E156-A160 VanDerWaalsContact O-N 3.08Å
157I98.8Very high96.8Very high0 Ų05.5 Ų5.50%03%0.027CC..Hα-helixtrans-72.1-35.9173.7-67.1168.2000110.8F99 F102 F110 F122 L141 I153 E154 H155 H159 A160 L161F99-I157 HydrophobicContact CD1-CD1 4.03Å; F99-I157 HydrophobicContact CE1-CD1 3.76Å; F102-I157 HydrophobicContact CD2-CD1 4.47Å; F102-I157 HydrophobicContact CD2-CG2 4.24Å; F102-I157 HydrophobicContact CE1-CG2 4.08Å; F102-I157 HydrophobicContact CE2-CB 3.72Å; F102-I157 HydrophobicContact CE2-CD1 3.87Å; F102-I157 HydrophobicContact CE2-CG1 4.41Å; F102-I157 HydrophobicContact CE2-CG2 3.41Å; F102-I157 VanDerWaalsContact CE2-CG2 3.41Å; F102-I157 HydrophobicContact CZ-CB 3.74Å; F102-I157 HydrophobicContact CZ-CG2 3.3Å; F110-I157 HydrophobicContact CE1-CG2 4.3Å; F110-I157 HydrophobicContact CZ-CD1 4.49Å; F110-I157 HydrophobicContact CZ-CG2 3.79Å; F122-I157 HydrophobicContact CE1-CD1 4.17Å; F122-I157 HydrophobicContact CE1-CG1 4.07Å; F122-I157 HydrophobicContact CZ-CD1 4.13Å; F122-I157 HydrophobicContact CZ-CG1 4.09Å; L141-I157 HydrophobicContact CD1-CG1 4.13Å; I153-I157 HydrophobicContact CG2-CD1 3.74Å; I153-I157 HydrophobicContact CG2-CG1 4.41Å; I153-I157 WeakPolarHBondContact O-CB 3.48Å; I153-I157 VanDerWaalsContact O-CG1 3.23Å; I153-I157 WeakPolarHBondContact O-CG1 3.45Å; I153-I157 PolarHBondContact O-N 2.95Å; E154-I157 PolarHBondContact O-N 2.86Å; H155-I157 VanDerWaalsContact C-N 3.27Å; H155-I157 PolarHBondContact O-N 3.02Å; I157-H159 VanDerWaalsContact C-N 3.32Å; I157-H159 PolarHBondContact O-N 2.78Å; I157-A160 CarbonylContact O-C 3.23Å; I157-A160 WeakPolarHBondContact O-CB 3.39Å; I157-A160 PolarHBondContact O-N 2.68Å; I157-A160 VanDerWaalsContact O-N 3.14Å; I157-L161 HydrophobicContact CG2-CD1 3.9Å; I157-L161 HydrophobicContact CG2-CG 4.32Å; I157-L161 WeakPolarHBondContact O-CB 3.46Å; I157-L161 VanDerWaalsContact O-CG 3.27Å; I157-L161 WeakPolarHBondContact O-CG 3.16Å; I157-L161 PolarHBondContact O-N 2.91Å
158L98.4Very high96.8Very high0 Ų05.5 Ų5.50%03%0.027CC..Hα-helixtrans-61.7-40.2172.4-79.5178.2000111.7F102 E154 H155 L161 G162 F163 L211 M212 F245 L253F102-L158 HydrophobicContact CE1-CD2 4.29Å; F102-L158 HydrophobicContact CZ-CG 4.47Å; E154-L158 WeakPolarHBondContact O-CG 2.89Å; E154-L158 PolarHBondContact O-N 3.38Å; H155-L158 WeakPolarHBondContact O-CB 3.38Å; H155-L158 PolarHBondContact O-N 2.94Å; L158-L161 HydrophobicContact CD2-CD1 4.35Å; L158-L161 CarbonylContact O-C 3.56Å; L158-L161 PolarHBondContact O-N 3.13Å; L158-L161 VanDerWaalsContact O-N 3.17Å; L158-G162 PolarHBondContact O-N 3.35Å; L158-G162 VanDerWaalsContact O-N 3.14Å; L158-F163 HydrophobicContact CB-CB 4.15Å; L158-F163 HydrophobicContact CB-CD2 4.42Å; L158-F163 HydrophobicContact CB-CG 4.31Å; L158-F163 HydrophobicContact CD2-CD2 3.98Å; L158-F163 HydrophobicContact CD2-CE2 4.05Å; L158-F163 HydrophobicContact CD2-CG 4.31Å; L158-F163 HydrophobicContact CD2-CZ 4.45Å; L158-F163 WeakPolarHBondContact O-CB 3.38Å; L158-F163 WeakPolarHBondContact O-CD2 3.45Å; L158-F163 PolarHBondContact O-N 2.97Å; L158-L211 HydrophobicContact CD1-CD2 4.26Å; L158-M212 HydrophobicContact CB-CE 4.18Å; L158-M212 HydrophobicContact CB-CG 4.49Å; L158-M212 HydrophobicContact CB-SD 3.55Å; L158-M212 VanDerWaalsContact CB-SD 3.55Å; L158-M212 HydrophobicContact CD1-CG 3.87Å; L158-M212 HydrophobicContact CD1-SD 3.49Å; L158-M212 WeakPolarHBondContact CD1-SD 3.43Å; L158-M212 HydrophobicContact CG-SD 4.19Å; L158-F245 HydrophobicContact CD1-CD1 3.8Å; L158-F245 HydrophobicContact CD1-CE1 3.76Å; L158-F245 HydrophobicContact CD2-CE1 4.2Å; L158-F245 HydrophobicContact CG-CD1 4.35Å; L158-F245 HydrophobicContact CG-CE1 3.85Å; L158-L253 HydrophobicContact CD2-CD1 4.44Å; L158-L253 HydrophobicContact CD2-CD2 4.31Å
159H97.8Very high96.8Very high0 Ų03.7 Ų3.70%02%0.017CC..Hα-helixtrans-55.6-52.7168.2-76.1-42.7000111.1D58 E131 V132 G133 H155 E156 I157 L161 G162 F163 H165 M212D58-H159 IonicContact OD1-NE2 2.88Å; D58-H159 PolarHBondContact OD1-NE2 3.09Å; D58-H159 IonicContact OD2-NE2 3.68Å; E131-H159 CarbonylContact O-C 3.6Å; E131-H159 VanDerWaalsContact O-C 3.31Å; V132-H159 VanDerWaalsContact CA-O 3.26Å; V132-H159 WeakPolarHBondContact CA-O 3.26Å; V132-H159 HydrophobicContact CG2-CB 4.42Å; G133-H159 PolarHBondContact N-O 2.97Å; G133-H159 VanDerWaalsContact N-O 3.13Å; H155-H159 AromaticContact CD2-CD2 3.66Å; H155-H159 AromaticContact CD2-NE2 3.59Å; H155-H159 AromaticContact CE1-NE2 3.99Å; H155-H159 AromaticContact NE2-CD2 3.65Å; H155-H159 AromaticContact NE2-CE1 3.99Å; H155-H159 AromaticContact NE2-NE2 3.05Å; H155-H159 PolarHBondContact NE2-NE2 2.82Å; H155-H159 PolarHBondContact O-N 2.89Å; E156-H159 WeakPolarHBondContact O-CB 3.25Å; E156-H159 PolarHBondContact O-N 2.94Å; E156-H159 IonicContact OE2-CD2 2.85Å; I157-H159 VanDerWaalsContact C-N 3.32Å; I157-H159 PolarHBondContact O-N 2.78Å; H159-L161 PolarHBondContact O-N 2.88Å; H159-L161 VanDerWaalsContact O-N 3.08Å; H159-G162 WeakPolarHBondContact O-CA 3.32Å; H159-G162 PolarHBondContact O-N 3.17Å; H159-F163 PolarHBondContact ND1-O 2.86Å; H159-H165 AromaticContact CE1-CE1 3.83Å; H159-H165 AromaticContact CE1-NE2 3.93Å; H159-H165 AromaticContact NE2-CE1 3.78Å; H159-H165 AromaticContact NE2-NE2 3.69Å; H159-M212 WeakPolarHBondContact CE1-CE 3.32Å; H159-M212 WeakPolarHBondContact ND1-CE 3.31Å; H159-M212 WeakPolarHBondContact NE2-CE 3.45Å
160A97.2Very high96.8Very high0 Ų05.7 Ų5.70%03%0.032CC..Hα-helixtrans-56.9-30.817800000113W75 I120 E131 G133 L141 E156 I157 G162W75-A160 PolarHBondContact NE1-O 2.85Å; I120-A160 HydrophobicContact CD1-CB 3.76Å; E131-A160 VanDerWaalsContact O-CA 3.28Å; E131-A160 WeakPolarHBondContact O-CA 3.46Å; E131-A160 PolarHBondContact O-N 2.78Å; G133-A160 CarbonylContact C-O 3.5Å; G133-A160 VanDerWaalsContact C-O 3.23Å; G133-A160 WeakPolarHBondContact CA-O 3.21Å; G133-A160 PolarHBondContact N-O 2.78Å; L141-A160 HydrophobicContact CD1-CB 4.42Å; E156-A160 PolarHBondContact O-N 3.08Å; E156-A160 VanDerWaalsContact O-N 3.08Å; I157-A160 CarbonylContact O-C 3.23Å; I157-A160 WeakPolarHBondContact O-CB 3.39Å; I157-A160 PolarHBondContact O-N 2.68Å; I157-A160 VanDerWaalsContact O-N 3.14Å; A160-G162 VanDerWaalsContact C-N 3.31Å
161L96.1Very high96.7Very high1 Ų17.2 Ų7.21%0.0054%0.041CC..Hα-helixtrans-78-11.6175.7-71.2165.2000113.8F77 I79 F102 V108 I157 L158 H159 F163 L253 M256 Y257F77-L161 HydrophobicContact CE1-CD2 3.9Å; F77-L161 HydrophobicContact CZ-CD2 4.07Å; I79-L161 HydrophobicContact CD1-CD2 3.79Å; F102-L161 HydrophobicContact CD1-CD1 4.25Å; F102-L161 HydrophobicContact CE1-CD1 3.52Å; F102-L161 HydrophobicContact CZ-CD1 4.05Å; V108-L161 HydrophobicContact CG1-CD1 4.35Å; V108-L161 HydrophobicContact CG1-CD2 4.2Å; V108-L161 HydrophobicContact CG2-CD1 4.19Å; V108-L161 HydrophobicContact CG2-CD2 4.32Å; I157-L161 HydrophobicContact CG2-CD1 3.9Å; I157-L161 HydrophobicContact CG2-CG 4.32Å; I157-L161 WeakPolarHBondContact O-CB 3.46Å; I157-L161 VanDerWaalsContact O-CG 3.27Å; I157-L161 WeakPolarHBondContact O-CG 3.16Å; I157-L161 PolarHBondContact O-N 2.91Å; L158-L161 HydrophobicContact CD2-CD1 4.35Å; L158-L161 CarbonylContact O-C 3.56Å; L158-L161 PolarHBondContact O-N 3.13Å; L158-L161 VanDerWaalsContact O-N 3.17Å; H159-L161 PolarHBondContact O-N 2.88Å; H159-L161 VanDerWaalsContact O-N 3.08Å; L161-F163 HydrophobicContact CB-CD2 4.42Å; L161-L253 HydrophobicContact CB-CD1 4.42Å; L161-L253 HydrophobicContact CD1-CD1 3.85Å; L161-M256 WeakPolarHBondContact O-CE 3.11Å; L161-Y257 HydrophobicContact CB-CE2 4.21Å; L161-Y257 HydrophobicContact CD2-CE2 3.78Å; L161-Y257 WeakPolarHBondContact CD2-OH 3.31Å; L161-Y257 PolarHBondContact O-OH 3.16Å
162G93.6Very high96.8Very high3 Ų37.2 Ų7.23%0.0314%0.04CC..THydrogen-bonded Turntrans1178.9173.800000115.3L68 L158 H159 A160L68-G162 WeakPolarHBondContact CA-O 3.49Å; L68-G162 WeakPolarHBondContact CB-O 3.35Å; L68-G162 VanDerWaalsContact CD1-O 3.31Å; L68-G162 WeakPolarHBondContact CD1-O 3.42Å; L68-G162 PolarHBondContact N-O 3.46Å; L158-G162 PolarHBondContact O-N 3.35Å; L158-G162 VanDerWaalsContact O-N 3.14Å; H159-G162 WeakPolarHBondContact O-CA 3.32Å; H159-G162 PolarHBondContact O-N 3.17Å; A160-G162 VanDerWaalsContact C-N 3.31Å
163F94.3Very high96.8Very high5 Ų511.2 Ų11.22%0.0226%0.061CC..  trans-83.6143-179-73.1-111.1000112L68 L158 H159 L161 M212 R252 L253 M256L68-F163 HydrophobicContact CD1-CD1 4.24Å; L68-F163 HydrophobicContact CD1-CD2 3.84Å; L68-F163 HydrophobicContact CD1-CE1 4.3Å; L68-F163 HydrophobicContact CD1-CE2 3.91Å; L68-F163 HydrophobicContact CD1-CG 3.99Å; L68-F163 HydrophobicContact CD1-CZ 4.13Å; L158-F163 HydrophobicContact CB-CB 4.15Å; L158-F163 HydrophobicContact CB-CD2 4.42Å; L158-F163 HydrophobicContact CB-CG 4.31Å; L158-F163 HydrophobicContact CD2-CD2 3.98Å; L158-F163 HydrophobicContact CD2-CE2 4.05Å; L158-F163 HydrophobicContact CD2-CG 4.31Å; L158-F163 HydrophobicContact CD2-CZ 4.45Å; L158-F163 WeakPolarHBondContact O-CB 3.38Å; L158-F163 WeakPolarHBondContact O-CD2 3.45Å; L158-F163 PolarHBondContact O-N 2.97Å; H159-F163 PolarHBondContact ND1-O 2.86Å; L161-F163 HydrophobicContact CB-CD2 4.42Å; F163-M212 HydrophobicContact CB-CE 4.36Å; F163-M212 HydrophobicContact CB-CG 4.45Å; F163-R252 HydrophobicContact CE1-CB 3.77Å; F163-R252 HydrophobicContact CZ-CB 3.98Å; F163-L253 HydrophobicContact CE2-CB 4.25Å; F163-L253 HydrophobicContact CE2-CD1 3.84Å; F163-L253 HydrophobicContact CZ-CB 3.89Å; F163-L253 HydrophobicContact CZ-CD1 4.34Å; F163-M256 HydrophobicContact CD2-CE 4.03Å; F163-M256 HydrophobicContact CE2-CE 3.44Å; F163-M256 VanDerWaalsContact CE2-CE 3.44Å; F163-M256 HydrophobicContact CZ-CE 4.31Å
164Y94.4Very high96.8Very high13 Ų1317 Ų175%0.0519%0.092CC..  trans-106.5174.6163.6-74.9-79.8000109.5F55 I59 N66 G67 V132 L198 I199F55-Y164 HydrophobicContact CD1-CE1 4.26Å; F55-Y164 HydrophobicContact CE1-CD1 4.02Å; F55-Y164 AromaticContact CE1-CE1 3.65Å; F55-Y164 HydrophobicContact CE1-CE1 3.65Å; I59-Y164 HydrophobicContact CD1-CD1 3.49Å; I59-Y164 VanDerWaalsContact CD1-CD1 3.49Å; I59-Y164 HydrophobicContact CD1-CE1 3.82Å; N66-Y164 PolarHBondContact O-OH 3.46Å; N66-Y164 VanDerWaalsContact O-OH 3.07Å; G67-Y164 VanDerWaalsContact CA-CE2 3.49Å; V132-Y164 HydrophobicContact CB-CE1 4.35Å; V132-Y164 HydrophobicContact CG1-CD2 4.26Å; V132-Y164 HydrophobicContact CG1-CE1 4.36Å; V132-Y164 HydrophobicContact CG1-CE2 3.83Å; V132-Y164 HydrophobicContact CG2-CD1 4.26Å; V132-Y164 HydrophobicContact CG2-CE1 3.79Å; Y164-L198 HydrophobicContact CE2-CD1 3.72Å; Y164-L198 HydrophobicContact CE2-CG 4.09Å; Y164-I199 HydrophobicContact CD2-CD1 4.48Å; Y164-I199 HydrophobicContact CD2-CG1 3.91Å; Y164-I199 HydrophobicContact CG-CD1 4.14Å; Y164-I199 HydrophobicContact CG-CG1 4.07Å
165H96.9Very high96.7Very high2 Ų220.4 Ų20.41%0.00911%0.106CC..  trans-69.4143.8179.6-65.3109.8000114.4Q56 D58 H155 H159 Q167 S168 M212 Y214Q56-H165 WeakPolarHBondContact CB-ND1 3.47Å; Q56-H165 PolarHBondContact O-CE1 2.79Å; Q56-H165 VanDerWaalsContact O-CE1 3.28Å; Q56-H165 PolarHBondContact OE1-ND1 3.14Å; Q56-H165 VanDerWaalsContact OE1-ND1 3.15Å; D58-H165 IonicContact OD1-CE1 3.76Å; D58-H165 PolarHBondContact OD1-CE1 3.23Å; D58-H165 IonicContact OD1-NE2 3.32Å; D58-H165 IonicContact OD2-CE1 3.13Å; D58-H165 IonicContact OD2-NE2 3.75Å; D58-H165 PolarHBondContact OD2-NE2 3Å; H155-H165 AromaticContact CE1-CD2 3.72Å; H155-H165 AromaticContact CE1-NE2 3.59Å; H155-H165 AromaticContact NE2-NE2 3.49Å; H155-H165 PolarHBondContact NE2-NE2 2.75Å; H159-H165 AromaticContact CE1-CE1 3.83Å; H159-H165 AromaticContact CE1-NE2 3.93Å; H159-H165 AromaticContact NE2-CE1 3.78Å; H159-H165 AromaticContact NE2-NE2 3.69Å; H165-Q167 PolarHBondContact O-N 2.67Å; H165-S168 WeakPolarHBondContact CB-OG 3.03Å; H165-S168 WeakPolarHBondContact O-CB 3.47Å; H165-S168 PolarHBondContact O-N 2.61Å; H165-S168 PolarHBondContact O-OG 3.2Å; H165-M212 CarbonylContact C-O 3.56Å; H165-M212 WeakPolarHBondContact CA-O 3.39Å; H165-M212 WeakPolarHBondContact CB-O 3.33Å; H165-M212 PolarHBondContact CD2-O 2.89Å; H165-M212 VanDerWaalsContact CD2-O 3.26Å; H165-Y214 AromaticContact CD2-CD1 3.97Å; H165-Y214 AromaticContact CD2-CE1 3.67Å; H165-Y214 AromaticContact CE1-CE1 3.68Å; H165-Y214 AromaticContact CG-CE1 3.98Å; H165-Y214 AromaticContact NE2-CE1 3.44Å; H165-Y214 WeakPolarHBondContact NE2-CE1 3.37Å
166E97.6Very high96.7Very high4 Ų420.4 Ų20.42%0.01911%0.106CC..G310 helixtrans-63.8-40.3-178.2-172.467.4-179.800112.6S168 R169 Y206 D207 M212 H213 R252E166-S168 PolarHBondContact O-N 3.23Å; E166-R169 VanDerWaalsContact CD-CD 3.46Å; E166-R169 WeakPolarHBondContact O-CG 3.09Å; E166-R169 PolarHBondContact O-N 2.73Å; E166-R169 WeakPolarHBondContact OE1-CD 3.27Å; E166-R169 IonicContact OE1-NE 2.66Å; E166-R169 IonicContact OE1-NH1 3.39Å; E166-Y206 HydrophobicContact CG-CD2 4.47Å; E166-Y206 HydrophobicContact CG-CE1 4.27Å; E166-Y206 HydrophobicContact CG-CE2 4.1Å; E166-Y206 WeakPolarHBondContact O-CE2 3.46Å; E166-D207 WeakPolarHBondContact CG-O 3.2Å; E166-D207 PolarHBondContact OE1-N 2.93Å; E166-M212 PolarHBondContact N-O 2.67Å; E166-H213 HydrophobicContact CB-CB 4.08Å; E166-R252 IonicContact OE1-CZ 3.76Å; E166-R252 IonicContact OE1-NH1 3.72Å; E166-R252 IonicContact OE1-NH2 3.73Å; E166-R252 PolarHBondContact OE1-NH2 3.44Å; E166-R252 IonicContact OE2-CZ 3.32Å; E166-R252 IonicContact OE2-NH1 3.75Å; E166-R252 PolarHBondContact OE2-NH1 2.77Å; E166-R252 IonicContact OE2-NH2 2.66Å; E166-R252 PolarHBondContact OE2-NH2 3.1Å
167Q96.9Very high96.7Very high0 Ų023.4 Ų23.40%012%0.122CC..G310 helixtrans-69.75179.680.1-72.6-19.400114.3H165 R172 Y206 Y214 I228H165-Q167 PolarHBondContact O-N 2.67Å; Q167-R172 WeakPolarHBondContact O-CD 3.24Å; Q167-R172 VanDerWaalsContact O-CG 3.24Å; Q167-R172 WeakPolarHBondContact O-CG 3.44Å; Q167-R172 PolarHBondContact O-NH1 2.81Å; Q167-Y206 WeakPolarHBondContact CA-OH 3.33Å; Q167-Y214 VanDerWaalsContact CD-CG 3.41Å; Q167-Y214 HydrophobicContact CG-CD2 4.08Å; Q167-Y214 HydrophobicContact CG-CG 4.16Å; Q167-Y214 VanDerWaalsContact NE2-CE1 3.27Å; Q167-Y214 VanDerWaalsContact NE2-CE2 3.31Å; Q167-Y214 VanDerWaalsContact NE2-CZ 3.32Å; Q167-I228 HydrophobicContact CB-CD1 3.75Å; Q167-I228 HydrophobicContact CG-CD1 4.24Å
168S95.8Very high96.7Very high0 Ų024.2 Ų24.20%013%0.126CC..G310 helixtrans-110.1-2.1-177.7-37.80000112.5Q56 H165 E166 T193 Y194Q56-S168 VanDerWaalsContact NE2-CB 3.34Å; Q56-S168 PolarHBondContact NE2-OG 3.08Å; H165-S168 WeakPolarHBondContact CB-OG 3.03Å; H165-S168 WeakPolarHBondContact O-CB 3.47Å; H165-S168 PolarHBondContact O-N 2.61Å; H165-S168 PolarHBondContact O-OG 3.2Å; E166-S168 PolarHBondContact O-N 3.23Å; S168-T193 WeakPolarHBondContact O-CA 3.39Å; S168-Y194 PolarHBondContact O-N 3.08Å
169R94.8Very high96.7Very high7 Ų730.3 Ų30.33%0.02615%0.149CC..SBendtrans-53.6149.1172.7-73.2174.654.2133.410111.2E166 D171 R172 I199 D201 T204 P205E166-R169 VanDerWaalsContact CD-CD 3.46Å; E166-R169 WeakPolarHBondContact O-CG 3.09Å; E166-R169 PolarHBondContact O-N 2.73Å; E166-R169 WeakPolarHBondContact OE1-CD 3.27Å; E166-R169 IonicContact OE1-NE 2.66Å; E166-R169 IonicContact OE1-NH1 3.39Å; R169-D171 VanDerWaalsContact CB-OD1 3.24Å; R169-D171 WeakPolarHBondContact CB-OD1 3.21Å; R169-D171 IonicContact CZ-OD1 3.23Å; R169-D171 IonicContact CZ-OD2 2.84Å; R169-D171 IonicContact NE-OD1 2.61Å; R169-D171 PolarHBondContact NE-OD1 3.44Å; R169-D171 IonicContact NE-OD2 3.4Å; R169-D171 IonicContact NH2-OD1 3.41Å; R169-D171 PolarHBondContact NH2-OD1 3Å; R169-D171 IonicContact NH2-OD2 3.38Å; R169-D171 PolarHBondContact NH2-OD2 3.21Å; R169-D171 PolarHBondContact O-N 3.08Å; R169-D171 VanDerWaalsContact O-N 3.17Å; R169-R172 HydrophobicContact CB-CB 4.39Å; R169-R172 WeakPolarHBondContact O-CB 3.47Å; R169-R172 WeakPolarHBondContact O-CG 2.97Å; R169-R172 PolarHBondContact O-N 3.12Å; R169-I199 HydrophobicContact CG-CG2 4.45Å; R169-D201 VanDerWaalsContact CZ-CB 3.47Å; R169-D201 IonicContact NH2-OD2 3.56Å; R169-D201 PolarHBondContact NH2-OD2 3.26Å; R169-T204 PolarHBondContact NH1-O 3.18Å; R169-T204 PolarHBondContact NH2-O 3.4Å; R169-P205 PolarHBondContact NH1-O 2.97Å
170T94.3Very high96.7Very high75 Ų7535.4 Ų35.446%0.4617%0.168SC..THydrogen-bonded Turntrans-59.4-26.7178.3-174.80000113.7Y194 D196T170-Y194 WeakPolarHBondContact CB-O 3.34Å; T170-Y194 PolarHBondContact N-O 3.39Å; T170-D196 WeakPolarHBondContact CG2-OD1 3.44Å
171D95.4Very high96.7Very high37 Ų3742 Ų4220%0.19820%0.203CC..THydrogen-bonded Turntrans-102.55.2-176.262.8-13.4000112.8R169 D173 D174 Y175R169-D171 VanDerWaalsContact CB-OD1 3.24Å; R169-D171 WeakPolarHBondContact CB-OD1 3.21Å; R169-D171 IonicContact CZ-OD1 3.23Å; R169-D171 IonicContact CZ-OD2 2.84Å; R169-D171 IonicContact NE-OD1 2.61Å; R169-D171 PolarHBondContact NE-OD1 3.44Å; R169-D171 IonicContact NE-OD2 3.4Å; R169-D171 IonicContact NH2-OD1 3.41Å; R169-D171 PolarHBondContact NH2-OD1 3Å; R169-D171 IonicContact NH2-OD2 3.38Å; R169-D171 PolarHBondContact NH2-OD2 3.21Å; R169-D171 PolarHBondContact O-N 3.08Å; R169-D171 VanDerWaalsContact O-N 3.17Å; D171-D173 PolarHBondContact O-N 2.95Å; D171-D173 VanDerWaalsContact O-N 3.09Å; D171-D174 WeakPolarHBondContact O-CB 3.31Å; D171-D174 PolarHBondContact O-N 3.43Å; D171-Y175 WeakPolarHBondContact O-CD2 3.41Å
172R97.3Very high96.8Very high3 Ų344.9 Ų44.91%0.01122%0.217CC..G310 helixtrans-57.9-31.5-173.572.498.6-171-99.5-0.7113.5Q167 R169 D174 Y175 V176 F191 T193 Y206Q167-R172 WeakPolarHBondContact O-CD 3.24Å; Q167-R172 VanDerWaalsContact O-CG 3.24Å; Q167-R172 WeakPolarHBondContact O-CG 3.44Å; Q167-R172 PolarHBondContact O-NH1 2.81Å; R169-R172 HydrophobicContact CB-CB 4.39Å; R169-R172 WeakPolarHBondContact O-CB 3.47Å; R169-R172 WeakPolarHBondContact O-CG 2.97Å; R169-R172 PolarHBondContact O-N 3.12Å; R172-D174 PolarHBondContact O-N 3.33Å; R172-D174 VanDerWaalsContact O-N 3.13Å; R172-Y175 PolarHBondContact O-N 2.95Å; R172-V176 HydrophobicContact CB-CG2 4.37Å; R172-V176 VanDerWaalsContact O-CG2 3.31Å; R172-V176 WeakPolarHBondContact O-CG2 3.34Å; R172-V176 PolarHBondContact O-N 2.04Å; R172-F191 PolarHBondContact NH1-O 3.04Å; R172-F191 PolarHBondContact NH2-O 2.98Å; R172-T193 HydrophobicContact CG-CG2 3.53Å; R172-Y206 HydrophobicContact CB-CD2 4.44Å; R172-Y206 HydrophobicContact CB-CE2 3.62Å
173D98Very high97Very high84 Ų8444.8 Ų44.845%0.44922%0.216SC..G310 helixtrans-65.5-12.9178.8-73.4-17.6000112.8D171 Y175 K231D171-D173 PolarHBondContact O-N 2.95Å; D171-D173 VanDerWaalsContact O-N 3.09Å; D173-Y175 VanDerWaalsContact C-N 3.33Å; D173-K231 WeakPolarHBondContact O-CE 3.41Å; D173-K231 PolarHBondContact O-NZ 2.92Å
174D98.2Very high97.1Very high121 Ų12146.7 Ų46.765%0.64723%0.226SC*.G310 helixtrans-79.3-17.5170.8-70.4-32.9000113D171 R172 K231D171-D174 WeakPolarHBondContact O-CB 3.31Å; D171-D174 PolarHBondContact O-N 3.43Å; R172-D174 PolarHBondContact O-N 3.33Å; R172-D174 VanDerWaalsContact O-N 3.13Å; D174-K231 WeakPolarHBondContact O-CD 3.26Å
175Y98.4Very high97.2Very high73 Ų7351.1 Ų51.129%0.28626%0.259SS..THydrogen-bonded Turntrans-114.4-32.6-171-63.3-83.4000113.6D171 R172 D173 Y206 Y208 K231D171-Y175 WeakPolarHBondContact O-CD2 3.41Å; R172-Y175 PolarHBondContact O-N 2.95Å; D173-Y175 VanDerWaalsContact C-N 3.33Å; Y175-Y206 HydrophobicContact CD1-CD1 4.18Å; Y175-Y206 AromaticContact CD1-CG 3.99Å; Y175-Y206 HydrophobicContact CD1-CG 3.99Å; Y175-Y206 HydrophobicContact CD2-CD1 4.35Å; Y175-Y206 AromaticContact CD2-CD2 3.67Å; Y175-Y206 HydrophobicContact CD2-CD2 3.67Å; Y175-Y206 HydrophobicContact CD2-CE2 4.49Å; Y175-Y206 AromaticContact CD2-CG 3.58Å; Y175-Y206 HydrophobicContact CD2-CG 3.58Å; Y175-Y206 HydrophobicContact CE1-CG 4.46Å; Y175-Y206 HydrophobicContact CE2-CD2 4.27Å; Y175-Y206 HydrophobicContact CE2-CG 4.11Å; Y175-Y206 AromaticContact CG-CD1 3.83Å; Y175-Y206 HydrophobicContact CG-CD1 3.83Å; Y175-Y206 AromaticContact CG-CD2 3.99Å; Y175-Y206 HydrophobicContact CG-CD2 3.99Å; Y175-Y206 AromaticContact CG-CG 3.51Å; Y175-Y206 HydrophobicContact CG-CG 3.51Å; Y175-Y208 WeakPolarHBondContact CA-OH 2.99Å; Y175-Y208 WeakPolarHBondContact CB-OH 3.31Å; Y175-Y208 HydrophobicContact CD1-CE2 4.35Å; Y175-Y208 PolarHBondContact O-OH 2.66Å; Y175-K231 PolarHBondContact O-N 2.57Å
176V98.6Very high97Very high1 Ų153.1 Ų53.11%0.00628%0.28CS..EExtended strand (participates in β ladder)trans-130.9158.2-176.8-60.20000111.4R172 I178 Y206 Y208 I228 T229R172-V176 HydrophobicContact CB-CG2 4.37Å; R172-V176 VanDerWaalsContact O-CG2 3.31Å; R172-V176 WeakPolarHBondContact O-CG2 3.34Å; R172-V176 PolarHBondContact O-N 2.04Å; V176-I178 HydrophobicContact CG2-CD1 4.2Å; V176-Y206 HydrophobicContact CG1-CE1 4.29Å; V176-Y208 HydrophobicContact CG1-CE1 4.06Å; V176-I228 HydrophobicContact CB-CD1 4.11Å; V176-I228 HydrophobicContact CB-CG1 4.01Å; V176-I228 HydrophobicContact CG1-CD1 4.22Å; V176-I228 HydrophobicContact CG1-CG1 4.32Å; V176-I228 HydrophobicContact CG2-CD1 3.95Å; V176-I228 HydrophobicContact CG2-CG1 4.27Å; V176-T229 CarbonylContact C-O 3.59Å; V176-T229 VanDerWaalsContact CA-O 3.3Å; V176-T229 WeakPolarHBondContact CA-O 3.39Å; V176-T229 WeakPolarHBondContact CB-O 3.44Å
177N98.4Very high97Very high62 Ų6255 Ų5533%0.33229%0.287SS..EExtended strand (participates in β ladder)trans-109.1131.5167.6-55.8-60.6000108.8I228 T229 K231N177-I228 WeakPolarHBondContact O-CA 3.5Å; N177-T229 PolarHBondContact N-O 2.88Å; N177-T229 PolarHBondContact O-N 2.79Å; N177-K231 VanDerWaalsContact OD1-CE 3.23Å; N177-K231 WeakPolarHBondContact OD1-CE 3.23Å
178I98.6Very high96.9Very high17 Ų1758.1 Ų58.19%0.08730%0.301CS..EExtended strand (participates in β ladder)trans-96.1122.8170.8-54.3-48000109.6V176 W180 I183 F191 I228V176-I178 HydrophobicContact CG2-CD1 4.2Å; I178-W180 HydrophobicContact CB-CZ2 4.25Å; I178-W180 HydrophobicContact CG2-CD2 3.76Å; I178-W180 HydrophobicContact CG2-CE3 4.18Å; I178-W180 HydrophobicContact CG2-CG 4.16Å; I178-W180 HydrophobicContact CG2-CH2 4.36Å; I178-W180 HydrophobicContact CG2-CZ2 3.95Å; I178-W180 HydrophobicContact CG2-CZ3 4.46Å; I178-W180 PolarHBondContact O-N 3.43Å; I178-I183 HydrophobicContact CG2-CD1 3.78Å; I178-F191 HydrophobicContact CD1-CD1 4.02Å; I178-F191 HydrophobicContact CG2-CB 4.07Å; I178-F191 HydrophobicContact CG2-CD1 4.04Å; I178-F191 HydrophobicContact CG2-CG 4.19Å; I178-I228 HydrophobicContact CD1-CB 4.08Å; I178-I228 HydrophobicContact CD1-CD1 3.72Å; I178-I228 HydrophobicContact CD1-CG1 3.77Å
179W98Very high96.8Very high129 Ų12961 Ų6149%0.48932%0.315SS..  trans-90.176.4177.3-62.2103000110.1D181 E182 I183 T227 T229W179-D181 PolarHBondContact O-N 2.83Å; W179-D181 VanDerWaalsContact O-N 3.13Å; W179-E182 HydrophobicContact CB-CB 4.08Å; W179-E182 HydrophobicContact CB-CG 4Å; W179-E182 WeakPolarHBondContact O-CB 3.38Å; W179-E182 PolarHBondContact O-N 2.7Å; W179-I183 PolarHBondContact O-N 2.86Å; W179-T227 PolarHBondContact N-O 2.87Å; W179-T229 PolarHBondContact NE1-OG1 2.88Å
180W98.1Very high96.9Very high106 Ų10660.6 Ų60.640%0.40231%0.313SS..G310 helixtrans-53.7-36-173.4-64.499.9000114.5I178 E182 I183 Q188 F191I178-W180 HydrophobicContact CB-CZ2 4.25Å; I178-W180 HydrophobicContact CG2-CD2 3.76Å; I178-W180 HydrophobicContact CG2-CE3 4.18Å; I178-W180 HydrophobicContact CG2-CG 4.16Å; I178-W180 HydrophobicContact CG2-CH2 4.36Å; I178-W180 HydrophobicContact CG2-CZ2 3.95Å; I178-W180 HydrophobicContact CG2-CZ3 4.46Å; I178-W180 PolarHBondContact O-N 3.43Å; W180-E182 PolarHBondContact O-N 2.04Å; W180-I183 HydrophobicContact CD2-CD1 4.27Å; W180-I183 HydrophobicContact CE3-CD1 3.65Å; W180-I183 HydrophobicContact CZ3-CD1 4.17Å; W180-I183 PolarHBondContact O-N 2.96Å; W180-Q188 HydrophobicContact CE3-CB 4.15Å; W180-Q188 HydrophobicContact CE3-CG 4.24Å; W180-Q188 HydrophobicContact CZ3-CB 4.02Å; W180-Q188 WeakPolarHBondContact CZ3-O 3.39Å; W180-F191 HydrophobicContact CH2-CB 3.88Å; W180-F191 HydrophobicContact CZ3-CB 3.94Å
181D97.8Very high97.1Very high138 Ų13857 Ų5774%0.73829%0.292SS*.G310 helixtrans-69.8-18.3178.8-68.2-34.3000113.2W179 K221W179-D181 PolarHBondContact O-N 2.83Å; W179-D181 VanDerWaalsContact O-N 3.13Å; D181-K221 WeakPolarHBondContact O-CD 3.47Å; D181-K221 PolarHBondContact O-NZ 2.8Å
182E97.9Very high97.1Very high63 Ų6358.6 Ų58.629%0.29430%0.3SS..G310 helixtrans-96.6-8.3-179.2-57-57.5149.900112.9W179 W180 N220 K221 V225 T227W179-E182 HydrophobicContact CB-CB 4.08Å; W179-E182 HydrophobicContact CB-CG 4Å; W179-E182 WeakPolarHBondContact O-CB 3.38Å; W179-E182 PolarHBondContact O-N 2.7Å; W180-E182 PolarHBondContact O-N 2.04Å; E182-N220 CarbonylContact O-C 3.54Å; E182-N220 WeakPolarHBondContact O-CA 3.37Å; E182-K221 WeakPolarHBondContact O-CG 3.4Å; E182-K221 PolarHBondContact O-N 2.99Å; E182-V225 HydrophobicContact CB-CG1 4.29Å; E182-V225 HydrophobicContact CG-CG1 3.69Å; E182-T227 HydrophobicContact CB-CG2 4.49Å
183I97.7Very high96.9Very high0 Ų061.2 Ų61.20%032%0.316CS..BIsolated β-bridgetrans-78137.8176.9-56.9166.8000110.2I178 W179 W180 S185 Q188 F191 F219 K221 T227I178-I183 HydrophobicContact CG2-CD1 3.78Å; W179-I183 PolarHBondContact O-N 2.86Å; W180-I183 HydrophobicContact CD2-CD1 4.27Å; W180-I183 HydrophobicContact CE3-CD1 3.65Å; W180-I183 HydrophobicContact CZ3-CD1 4.17Å; W180-I183 PolarHBondContact O-N 2.96Å; I183-S185 PolarHBondContact O-N 2.82Å; I183-Q188 HydrophobicContact CG2-CG 4.42Å; I183-F191 HydrophobicContact CD1-CB 4.27Å; I183-F191 HydrophobicContact CD1-CD1 4.38Å; I183-F191 HydrophobicContact CD1-CD2 3.51Å; I183-F191 HydrophobicContact CD1-CE2 3.84Å; I183-F191 HydrophobicContact CD1-CG 3.8Å; I183-F191 HydrophobicContact CD1-CZ 4.41Å; I183-F191 HydrophobicContact CG1-CD2 4.12Å; I183-F191 HydrophobicContact CG1-CE2 3.92Å; I183-F191 HydrophobicContact CG1-CZ 4.3Å; I183-F191 HydrophobicContact CG2-CD2 4.09Å; I183-F191 HydrophobicContact CG2-CE2 3.76Å; I183-F219 HydrophobicContact CG2-CB 4.4Å; I183-K221 WeakPolarHBondContact O-CD 3.36Å; I183-K221 WeakPolarHBondContact O-CE 3.45Å; I183-K221 PolarHBondContact O-NZ 2.88Å; I183-T227 HydrophobicContact CB-CG2 4.34Å; I183-T227 HydrophobicContact CG1-CG2 3.76Å
184L96.6Very high96.5Very high46 Ų4658.1 Ų58.124%0.24130%0.299CS..PPolyproline II helixtrans-50.4137.7173.8-74.6167.4000111.7L48 G186 Y187 F219 N220 K221L48-L184 HydrophobicContact CD1-CD1 4.28Å; L48-L184 HydrophobicContact CD2-CD1 3.46Å; L48-L184 VanDerWaalsContact CD2-CD1 3.46Å; L184-G186 PolarHBondContact O-N 2.82Å; L184-Y187 HydrophobicContact CB-CD2 3.75Å; L184-Y187 HydrophobicContact CB-CG 4.29Å; L184-Y187 PolarHBondContact O-N 2.94Å; L184-F219 WeakPolarHBondContact CG-O 3.47Å; L184-F219 PolarHBondContact N-O 3.24Å; L184-N220 WeakPolarHBondContact CG-O 3.03Å; L184-K221 HydrophobicContact CD2-CG 4.09Å; L184-K221 HydrophobicContact CG-CG 4.46Å
185S96.2Very high95.9Very high105 Ų10556.7 Ų56.773%0.73429%0.291SS*.THydrogen-bonded Turntrans-62.3124.9-178.9-173.60000110.4I183I183-S185 PolarHBondContact O-N 2.82Å
186G93.4Very high95Very high44 Ų4457.7 Ų57.745%0.45430%0.301SS..THydrogen-bonded Turntrans101.3-20.9-176.400000113.5L184 H189L184-G186 PolarHBondContact O-N 2.82Å; G186-H189 PolarHBondContact O-CE1 3.12Å; G186-H189 VanDerWaalsContact O-CE1 3.27Å; G186-H189 PolarHBondContact O-ND1 2.92Å
187Y95.9Very high94Very high43 Ų4361.4 Ų61.417%0.16933%0.327CS..  trans-98.36.4-174.7-70.3-91.2000114L48 L184 H189 N190 F219L48-Y187 HydrophobicContact CD1-CE1 3.81Å; L48-Y187 HydrophobicContact CD1-CE2 3.88Å; L48-Y187 VanDerWaalsContact CD1-OH 3.29Å; L48-Y187 WeakPolarHBondContact CD1-OH 3.36Å; L184-Y187 HydrophobicContact CB-CD2 3.75Å; L184-Y187 HydrophobicContact CB-CG 4.29Å; L184-Y187 PolarHBondContact O-N 2.94Å; Y187-H189 PolarHBondContact O-N 2.7Å; Y187-N190 WeakPolarHBondContact O-CB 3.46Å; Y187-N190 PolarHBondContact O-N 3.07Å; Y187-F219 AromaticContact CD1-CD1 3.54Å; Y187-F219 HydrophobicContact CD1-CD1 3.54Å; Y187-F219 AromaticContact CD1-CE1 3.75Å; Y187-F219 HydrophobicContact CD1-CE1 3.75Å; Y187-F219 HydrophobicContact CD1-CG 4.39Å; Y187-F219 HydrophobicContact CE1-CD1 4.15Å; Y187-F219 HydrophobicContact CE1-CE1 4.09Å; Y187-F219 HydrophobicContact CG-CD1 4.04Å
188Q96.6Very high93.1Very high66 Ų6659.1 Ų59.131%0.30832%0.315SS..G310 helixtrans-57.9-34.9179.1-67.988.6-13.100112.4W180 I183 N190 F191W180-Q188 HydrophobicContact CE3-CB 4.15Å; W180-Q188 HydrophobicContact CE3-CG 4.24Å; W180-Q188 HydrophobicContact CZ3-CB 4.02Å; W180-Q188 WeakPolarHBondContact CZ3-O 3.39Å; I183-Q188 HydrophobicContact CG2-CG 4.42Å; Q188-N190 PolarHBondContact O-N 3.49Å; Q188-N190 VanDerWaalsContact O-N 3.11Å; Q188-F191 PolarHBondContact O-N 2.87Å
189H93.3Very high92.4Very high60 Ų6059 Ų5928%0.27831%0.314SS..G310 helixtrans-60.7-22.2-178.868.9-91.3000113.8D53 G186 Y187 F191 D192D53-H189 IonicContact OD1-CE1 2.75Å; D53-H189 PolarHBondContact OD1-CE1 2.87Å; D53-H189 IonicContact OD1-NE2 2.96Å; G186-H189 PolarHBondContact O-CE1 3.12Å; G186-H189 VanDerWaalsContact O-CE1 3.27Å; G186-H189 PolarHBondContact O-ND1 2.92Å; Y187-H189 PolarHBondContact O-N 2.7Å; H189-F191 PolarHBondContact O-N 2.77Å; H189-D192 WeakPolarHBondContact CA-OD2 3.38Å; H189-D192 PolarHBondContact O-N 3.04Å
190N96.3Very high91.6Very high0 Ų054 Ų540%030%0.298CS..G310 helixtrans-67.9-17.7175.2-69.5-21.3000113.1Q56 G57 Y187 Q188 Y214 F219Q56-N190 WeakPolarHBondContact CA-OD1 3.16Å; Q56-N190 PolarHBondContact N-OD1 3.34Å; G57-N190 PolarHBondContact N-OD1 2.84Å; Y187-N190 WeakPolarHBondContact O-CB 3.46Å; Y187-N190 PolarHBondContact O-N 3.07Å; Q188-N190 PolarHBondContact O-N 3.49Å; Q188-N190 VanDerWaalsContact O-N 3.11Å; N190-Y214 HydrophobicContact CB-CE2 4.4Å; N190-F219 HydrophobicContact CB-CD2 4.34Å; N190-F219 HydrophobicContact CB-CE2 4.15Å; N190-F219 WeakPolarHBondContact ND2-CZ 3.39Å
191F97.6Very high90.9Very high0 Ų051.5 Ų51.50%029%0.293CS..G310 helixtrans-104.810.9178.4-61.5-97.7000112R172 I178 W180 I183 Q188 H189 Y214 S218 F219 T227R172-F191 PolarHBondContact NH1-O 3.04Å; R172-F191 PolarHBondContact NH2-O 2.98Å; I178-F191 HydrophobicContact CD1-CD1 4.02Å; I178-F191 HydrophobicContact CG2-CB 4.07Å; I178-F191 HydrophobicContact CG2-CD1 4.04Å; I178-F191 HydrophobicContact CG2-CG 4.19Å; W180-F191 HydrophobicContact CH2-CB 3.88Å; W180-F191 HydrophobicContact CZ3-CB 3.94Å; I183-F191 HydrophobicContact CD1-CB 4.27Å; I183-F191 HydrophobicContact CD1-CD1 4.38Å; I183-F191 HydrophobicContact CD1-CD2 3.51Å; I183-F191 HydrophobicContact CD1-CE2 3.84Å; I183-F191 HydrophobicContact CD1-CG 3.8Å; I183-F191 HydrophobicContact CD1-CZ 4.41Å; I183-F191 HydrophobicContact CG1-CD2 4.12Å; I183-F191 HydrophobicContact CG1-CE2 3.92Å; I183-F191 HydrophobicContact CG1-CZ 4.3Å; I183-F191 HydrophobicContact CG2-CD2 4.09Å; I183-F191 HydrophobicContact CG2-CE2 3.76Å; Q188-F191 PolarHBondContact O-N 2.87Å; H189-F191 PolarHBondContact O-N 2.77Å; F191-Y214 HydrophobicContact CE1-CD2 4.01Å; F191-Y214 HydrophobicContact CE1-CE2 4.4Å; F191-Y214 HydrophobicContact CZ-CD2 4.2Å; F191-Y214 HydrophobicContact CZ-CE2 4.33Å; F191-S218 WeakPolarHBondContact CZ-O 3.29Å; F191-F219 HydrophobicContact CE2-CB 4.09Å; F191-F219 AromaticContact CE2-CD2 3.93Å; F191-F219 HydrophobicContact CE2-CD2 3.93Å; F191-F219 HydrophobicContact CE2-CG 4.41Å; F191-F219 HydrophobicContact CZ-CB 4.4Å; F191-F219 HydrophobicContact CZ-CD2 4.12Å; F191-T227 HydrophobicContact CZ-CG2 4.47Å
192D95.8Very high90.5Very high70 Ų7046.9 Ų46.937%0.37427%0.267SS..  trans-68.1146.3175.4-70.2-21.7000111.1H189 Y194H189-D192 WeakPolarHBondContact CA-OD2 3.38Å; H189-D192 PolarHBondContact O-N 3.04Å; D192-Y194 HydrophobicContact CB-CE2 4.46Å; D192-Y194 WeakPolarHBondContact O-CE2 3.3Å
193T94Very high90.2Very high58 Ų5850.4 Ų50.436%0.35629%0.289SS..  trans-89151.8170.956.90000110.5S168 R172S168-T193 WeakPolarHBondContact O-CA 3.39Å; R172-T193 HydrophobicContact CG-CG2 3.53Å
194Y89.8Confident90.1Very high19 Ų1950.7 Ų50.78%0.07529%0.29CS..  trans-123.6150.7177.1-55.2-84.4000111.6F55 R65 S168 T170 D192 L198 I199F55-Y194 HydrophobicContact CE2-CE1 4.02Å; F55-Y194 AromaticContact CE2-CZ 3.65Å; F55-Y194 WeakPolarHBondContact CE2-OH 3.45Å; F55-Y194 AromaticContact CZ-CE1 3.71Å; F55-Y194 HydrophobicContact CZ-CE1 3.71Å; F55-Y194 AromaticContact CZ-CE2 3.9Å; F55-Y194 HydrophobicContact CZ-CE2 3.9Å; F55-Y194 AromaticContact CZ-CZ 3.31Å; F55-Y194 WeakPolarHBondContact CZ-OH 3.36Å; R65-Y194 VanDerWaalsContact NH1-CE1 3.3Å; S168-Y194 PolarHBondContact O-N 3.08Å; T170-Y194 WeakPolarHBondContact CB-O 3.34Å; T170-Y194 PolarHBondContact N-O 3.39Å; D192-Y194 HydrophobicContact CB-CE2 4.46Å; D192-Y194 WeakPolarHBondContact O-CE2 3.3Å; Y194-L198 HydrophobicContact CD1-CD2 3.66Å; Y194-L198 HydrophobicContact CE1-CD2 4.46Å; Y194-L198 HydrophobicContact CG-CD2 3.83Å; Y194-I199 HydrophobicContact CD2-CD1 3.61Å; Y194-I199 HydrophobicContact CG-CD1 4.07Å
195D86.1Confident90.1Very high90 Ų9052.2 Ų52.248%0.48130%0.303SS..  trans-70.7166.1179.66547.8000112.8S197 L198 I199D195-S197 PolarHBondContact O-N 2.88Å; D195-S197 VanDerWaalsContact OD1-CA 3.26Å; D195-S197 WeakPolarHBondContact OD1-CA 3.32Å; D195-S197 WeakPolarHBondContact OD1-CB 3.33Å; D195-S197 PolarHBondContact OD1-N 2.9Å; D195-S197 PolarHBondContact OD1-OG 3.15Å; D195-L198 PolarHBondContact O-N 2.82Å; D195-L198 PolarHBondContact OD1-N 3.04Å; D195-I199 PolarHBondContact O-N 2.91Å
196D79.3Confident90.2Very high95 Ų9547.8 Ų47.851%0.50827%0.27SS..THydrogen-bonded Turntrans-64.3-9.4178.8-63.6-19.6000114.3T170 I199T170-D196 WeakPolarHBondContact CG2-OD1 3.44Å; D196-I199 VanDerWaalsContact CA-O 3.31Å; D196-I199 WeakPolarHBondContact CA-O 3.28Å
197S77.1Confident90.4Very high79 Ų7946.1 Ų46.155%0.55225%0.251SS*.THydrogen-bonded Turntrans-78.4-25.3173.285.60000111.8D195D195-S197 PolarHBondContact O-N 2.88Å; D195-S197 VanDerWaalsContact OD1-CA 3.26Å; D195-S197 WeakPolarHBondContact OD1-CA 3.32Å; D195-S197 WeakPolarHBondContact OD1-CB 3.33Å; D195-S197 PolarHBondContact OD1-N 2.9Å; D195-S197 PolarHBondContact OD1-OG 3.15Å
198L79.3Confident90.5Very high13 Ų1345.2 Ų45.27%0.06825%0.247CC..THydrogen-bonded Turntrans-101.9-50177.6-17958.1000113.2R65 Y164 Y194 D195R65-L198 HydrophobicContact CB-CD1 3.56Å; R65-L198 HydrophobicContact CB-CD2 4.03Å; R65-L198 HydrophobicContact CB-CG 4.47Å; R65-L198 HydrophobicContact CG-CD2 4.41Å; R65-L198 WeakPolarHBondContact O-CD1 3.13Å; Y164-L198 HydrophobicContact CE2-CD1 3.72Å; Y164-L198 HydrophobicContact CE2-CG 4.09Å; Y194-L198 HydrophobicContact CD1-CD2 3.66Å; Y194-L198 HydrophobicContact CE1-CD2 4.46Å; Y194-L198 HydrophobicContact CG-CD2 3.83Å; D195-L198 PolarHBondContact O-N 2.82Å; D195-L198 PolarHBondContact OD1-N 3.04Å
199I82.9Confident90.5Very high14 Ų1445 Ų457%0.07225%0.247CC..  trans-113.2122.2-178.2-59-176000108Y164 R169 Y194 D195 D196Y164-I199 HydrophobicContact CD2-CD1 4.48Å; Y164-I199 HydrophobicContact CD2-CG1 3.91Å; Y164-I199 HydrophobicContact CG-CD1 4.14Å; Y164-I199 HydrophobicContact CG-CG1 4.07Å; R169-I199 HydrophobicContact CG-CG2 4.45Å; Y194-I199 HydrophobicContact CD2-CD1 3.61Å; Y194-I199 HydrophobicContact CG-CD1 4.07Å; D195-I199 PolarHBondContact O-N 2.91Å; D196-I199 VanDerWaalsContact CA-O 3.31Å; D196-I199 WeakPolarHBondContact CA-O 3.28Å
200T82.7Confident90.7Very high26 Ų2642.2 Ų42.216%0.1623%0.233CC..  trans-111.6139.1172.3176.70000110.5L68 R69 L202L68-T200 HydrophobicContact CB-CG2 4.03Å; L68-T200 HydrophobicContact CD2-CG2 3.55Å; L68-T200 WeakPolarHBondContact CD2-O 3.48Å; L68-T200 HydrophobicContact CG-CG2 4.01Å; R69-T200 HydrophobicContact CB-CG2 4.42Å; T200-L202 HydrophobicContact CG2-CD2 3.78Å; T200-L202 HydrophobicContact CG2-CG 4.11Å; T200-L202 PolarHBondContact O-N 2.91Å; T200-L202 PolarHBondContact OG1-N 3.5Å
201D82.8Confident90.8Very high53 Ų5342.2 Ų42.228%0.28323%0.233SC..  trans-79.2-6.7174.263.91000113R169 N203 T204 R252R169-D201 VanDerWaalsContact CZ-CB 3.47Å; R169-D201 IonicContact NH2-OD2 3.56Å; R169-D201 PolarHBondContact NH2-OD2 3.26Å; D201-N203 PolarHBondContact O-N 3.26Å; D201-N203 VanDerWaalsContact O-N 3.14Å; D201-N203 PolarHBondContact OD1-N 2.81Å; D201-T204 PolarHBondContact O-N 3.11Å; D201-T204 VanDerWaalsContact O-N 3.07Å; D201-T204 PolarHBondContact O-OG1 3.33Å; D201-T204 VanDerWaalsContact O-OG1 3.09Å; D201-R252 PolarHBondContact O-NE 2.85Å; D201-R252 VanDerWaalsContact O-NE 3.08Å
202L88.9Confident90.8Very high40 Ų4042.3 Ų42.321%0.20923%0.234CC..THydrogen-bonded Turntrans47.436.5-171-62.4174.7000112.5L68 T200 R252 R255 M256L68-L202 HydrophobicContact CD2-CD1 4.12Å; L68-L202 HydrophobicContact CD2-CG 4.11Å; T200-L202 HydrophobicContact CG2-CD2 3.78Å; T200-L202 HydrophobicContact CG2-CG 4.11Å; T200-L202 PolarHBondContact O-N 2.91Å; T200-L202 PolarHBondContact OG1-N 3.5Å; L202-R252 HydrophobicContact CB-CG 4.41Å; L202-R252 HydrophobicContact CD1-CB 4.17Å; L202-R252 WeakPolarHBondContact CD1-O 3.07Å; L202-R255 PolarHBondContact O-NH1 3.04Å; L202-M256 HydrophobicContact CD1-CB 3.94Å
203N92.1Very high91Very high138 Ų13839 Ų3974%0.73822%0.216SC*.THydrogen-bonded Turntrans55.549.8-176.8-169.554.1000112.6D201 R255D201-N203 PolarHBondContact O-N 3.26Å; D201-N203 VanDerWaalsContact O-N 3.14Å; D201-N203 PolarHBondContact OD1-N 2.81Å; N203-R255 PolarHBondContact O-NH1 3.14Å
204T95.3Very high91.2Very high5 Ų536.4 Ų36.43%0.03120%0.2CC..  trans-119.4150.816876.10000110.6R169 D201 I248 E251 R252R169-T204 PolarHBondContact NH1-O 3.18Å; R169-T204 PolarHBondContact NH2-O 3.4Å; D201-T204 PolarHBondContact O-N 3.11Å; D201-T204 VanDerWaalsContact O-N 3.07Å; D201-T204 PolarHBondContact O-OG1 3.33Å; D201-T204 VanDerWaalsContact O-OG1 3.09Å; T204-I248 HydrophobicContact CG2-CG2 4.22Å; T204-I248 VanDerWaalsContact OG1-CG2 3.31Å; T204-I248 WeakPolarHBondContact OG1-CG2 3.23Å; T204-E251 HydrophobicContact CG2-CG 4.18Å; T204-R252 HydrophobicContact CG2-CG 3.75Å; T204-R252 VanDerWaalsContact OG1-CZ 3.25Å; T204-R252 PolarHBondContact OG1-NE 2.84Å; T204-R252 PolarHBondContact OG1-NH2 3.19Å
205P97.3Very high91.4Very high79 Ų7938 Ų3851%0.51321%0.208SC..  trans-61.7163.8175.126.8-34.4000111.7R169 D207 I248 R252R169-P205 PolarHBondContact NH1-O 2.97Å; P205-D207 PolarHBondContact O-N 3.03Å; P205-I248 HydrophobicContact CG-CD1 3.95Å; P205-R252 PolarHBondContact O-NH2 3.39Å
206Y97.9Very high91.9Very high11 Ų1134.7 Ų34.74%0.04319%0.191CC..  trans-60.9131.6170.3-169.4-83.9000110.3E166 Q167 R172 Y175 V176 Y208 H213E166-Y206 HydrophobicContact CG-CD2 4.47Å; E166-Y206 HydrophobicContact CG-CE1 4.27Å; E166-Y206 HydrophobicContact CG-CE2 4.1Å; E166-Y206 WeakPolarHBondContact O-CE2 3.46Å; Q167-Y206 WeakPolarHBondContact CA-OH 3.33Å; R172-Y206 HydrophobicContact CB-CD2 4.44Å; R172-Y206 HydrophobicContact CB-CE2 3.62Å; Y175-Y206 HydrophobicContact CD1-CD1 4.18Å; Y175-Y206 AromaticContact CD1-CG 3.99Å; Y175-Y206 HydrophobicContact CD1-CG 3.99Å; Y175-Y206 HydrophobicContact CD2-CD1 4.35Å; Y175-Y206 AromaticContact CD2-CD2 3.67Å; Y175-Y206 HydrophobicContact CD2-CD2 3.67Å; Y175-Y206 HydrophobicContact CD2-CE2 4.49Å; Y175-Y206 AromaticContact CD2-CG 3.58Å; Y175-Y206 HydrophobicContact CD2-CG 3.58Å; Y175-Y206 HydrophobicContact CE1-CG 4.46Å; Y175-Y206 HydrophobicContact CE2-CD2 4.27Å; Y175-Y206 HydrophobicContact CE2-CG 4.11Å; Y175-Y206 AromaticContact CG-CD1 3.83Å; Y175-Y206 HydrophobicContact CG-CD1 3.83Å; Y175-Y206 AromaticContact CG-CD2 3.99Å; Y175-Y206 HydrophobicContact CG-CD2 3.99Å; Y175-Y206 AromaticContact CG-CG 3.51Å; Y175-Y206 HydrophobicContact CG-CG 3.51Å; V176-Y206 HydrophobicContact CG1-CE1 4.29Å; Y206-Y208 HydrophobicContact CD1-CD1 4.16Å; Y206-Y208 HydrophobicContact CD1-CE1 4.11Å; Y206-Y208 HydrophobicContact CD1-CE2 4.5Å; Y206-Y208 HydrophobicContact CD1-CG 4.4Å; Y206-Y208 AromaticContact CE1-CD1 3.89Å; Y206-Y208 HydrophobicContact CE1-CD1 3.89Å; Y206-Y208 AromaticContact CE1-CE1 3.95Å; Y206-Y208 HydrophobicContact CE1-CE1 3.95Å; Y206-Y208 HydrophobicContact CE1-CG 4.47Å; Y206-H213 AromaticContact CE1-CD2 3.84Å; Y206-H213 AromaticContact CE1-NE2 3.63Å; Y206-H213 AromaticContact CZ-CD2 3.87Å; Y206-H213 AromaticContact CZ-NE2 3.58Å; Y206-H213 PolarHBondContact OH-CD2 3.39Å; Y206-H213 VanDerWaalsContact OH-CD2 3.3Å; Y206-H213 PolarHBondContact OH-NE2 2.93Å
207D98Very high92.6Very high10 Ų1034.6 Ų34.65%0.05319%0.187CC..  trans-112.299.9-172-178.118.5000112.8E166 P205 E209 S210 S246 I248E166-D207 WeakPolarHBondContact CG-O 3.2Å; E166-D207 PolarHBondContact OE1-N 2.93Å; P205-D207 PolarHBondContact O-N 3.03Å; D207-E209 PolarHBondContact O-N 3.26Å; D207-E209 WeakPolarHBondContact OD1-CA 3.44Å; D207-E209 WeakPolarHBondContact OD1-CB 3.27Å; D207-E209 PolarHBondContact OD1-N 2.74Å; D207-S210 VanDerWaalsContact CG-N 3.29Å; D207-S210 WeakPolarHBondContact O-CB 3.32Å; D207-S210 PolarHBondContact O-N 2.78Å; D207-S210 PolarHBondContact OD1-N 2.97Å; D207-S210 VanDerWaalsContact OD2-CA 3.25Å; D207-S210 WeakPolarHBondContact OD2-CA 3.5Å; D207-S210 WeakPolarHBondContact OD2-CB 3.48Å; D207-S210 PolarHBondContact OD2-N 3.45Å; D207-S210 VanDerWaalsContact OD2-N 3.16Å; D207-S246 WeakPolarHBondContact OD2-CB 3.37Å; D207-S246 PolarHBondContact OD2-OG 3.05Å; D207-I248 HydrophobicContact CB-CB 4.04Å; D207-I248 HydrophobicContact CB-CD1 3.85Å; D207-I248 HydrophobicContact CB-CG2 4.02Å
208Y97.8Very high93.5Very high23 Ų2330.9 Ų30.99%0.0916%0.161CC..THydrogen-bonded Turntrans-64.6-22.6174.2-62-74.8000113.3Y175 V176 Y206 A230 F235 I239Y175-Y208 WeakPolarHBondContact CA-OH 2.99Å; Y175-Y208 WeakPolarHBondContact CB-OH 3.31Å; Y175-Y208 HydrophobicContact CD1-CE2 4.35Å; Y175-Y208 PolarHBondContact O-OH 2.66Å; V176-Y208 HydrophobicContact CG1-CE1 4.06Å; Y206-Y208 HydrophobicContact CD1-CD1 4.16Å; Y206-Y208 HydrophobicContact CD1-CE1 4.11Å; Y206-Y208 HydrophobicContact CD1-CE2 4.5Å; Y206-Y208 HydrophobicContact CD1-CG 4.4Å; Y206-Y208 AromaticContact CE1-CD1 3.89Å; Y206-Y208 HydrophobicContact CE1-CD1 3.89Å; Y206-Y208 AromaticContact CE1-CE1 3.95Å; Y206-Y208 HydrophobicContact CE1-CE1 3.95Å; Y206-Y208 HydrophobicContact CE1-CG 4.47Å; Y208-A230 HydrophobicContact CD1-CB 4.38Å; Y208-A230 HydrophobicContact CE1-CB 3.91Å; Y208-F235 HydrophobicContact CD1-CB 3.85Å; Y208-F235 HydrophobicContact CD1-CG 4.24Å; Y208-F235 HydrophobicContact CD2-CB 4.18Å; Y208-F235 AromaticContact CD2-CD1 3.68Å; Y208-F235 HydrophobicContact CD2-CD1 3.68Å; Y208-F235 AromaticContact CD2-CD2 3.86Å; Y208-F235 HydrophobicContact CD2-CD2 3.86Å; Y208-F235 HydrophobicContact CD2-CE1 4.01Å; Y208-F235 HydrophobicContact CD2-CE2 4.14Å; Y208-F235 AromaticContact CD2-CG 3.65Å; Y208-F235 HydrophobicContact CD2-CG 3.65Å; Y208-F235 HydrophobicContact CD2-CZ 4.23Å; Y208-F235 HydrophobicContact CE1-CB 4.21Å; Y208-F235 HydrophobicContact CE1-CG 4.49Å; Y208-F235 HydrophobicContact CE2-CD1 4.34Å; Y208-F235 AromaticContact CE2-CD2 3.67Å; Y208-F235 HydrophobicContact CE2-CD2 3.67Å; Y208-F235 AromaticContact CE2-CE2 3.88Å; Y208-F235 HydrophobicContact CE2-CE2 3.88Å; Y208-F235 AromaticContact CE2-CG 3.94Å; Y208-F235 HydrophobicContact CE2-CG 3.94Å; Y208-F235 HydrophobicContact CE2-CZ 4.34Å; Y208-F235 HydrophobicContact CG-CB 3.82Å; Y208-F235 AromaticContact CG-CD1 3.91Å; Y208-F235 HydrophobicContact CG-CD1 3.91Å; Y208-F235 HydrophobicContact CG-CD2 4.36Å; Y208-F235 AromaticContact CG-CG 3.79Å; Y208-F235 HydrophobicContact CG-CG 3.79Å; Y208-I239 HydrophobicContact CD1-CG2 3.68Å; Y208-I239 HydrophobicContact CG-CG2 4.34Å; Y208-I239 VanDerWaalsContact O-CA 3.32Å; Y208-I239 WeakPolarHBondContact O-CA 3.33Å
209E96.4Very high94.3Very high63 Ų6330.6 Ų30.629%0.29416%0.159SC..THydrogen-bonded Turntrans-89.6-1178.2-73.5-169.8165.400112.9D207 L211 I238 Q241 R579D207-E209 PolarHBondContact O-N 3.26Å; D207-E209 WeakPolarHBondContact OD1-CA 3.44Å; D207-E209 WeakPolarHBondContact OD1-CB 3.27Å; D207-E209 PolarHBondContact OD1-N 2.74Å; E209-L211 PolarHBondContact O-N 3.45Å; E209-I238 HydrophobicContact CB-CG2 4.31Å; E209-I238 HydrophobicContact CG-CG2 3.31Å; E209-Q241 VanDerWaalsContact O-CG 3.25Å; E209-Q241 WeakPolarHBondContact O-CG 3.29Å; E209-Q241 PolarHBondContact O-NE2 2.65Å; E209-R579 IonicContact OE1-NH1 3.89Å; E209-R579 PolarHBondContact OE1-NH1 2.85Å; E209-R579 IonicContact OE2-NH1 2.74Å; E209-R579 PolarHBondContact OE2-NH1 3.13Å
210S98.1Very high94.9Very high0 Ų031.5 Ų31.50%016%0.164CC..  trans-57.5132.9-175.8177.70000111D207 M212 H213 D249D207-S210 VanDerWaalsContact CG-N 3.29Å; D207-S210 WeakPolarHBondContact O-CB 3.32Å; D207-S210 PolarHBondContact O-N 2.78Å; D207-S210 PolarHBondContact OD1-N 2.97Å; D207-S210 VanDerWaalsContact OD2-CA 3.25Å; D207-S210 WeakPolarHBondContact OD2-CA 3.5Å; D207-S210 WeakPolarHBondContact OD2-CB 3.48Å; D207-S210 PolarHBondContact OD2-N 3.45Å; D207-S210 VanDerWaalsContact OD2-N 3.16Å; S210-M212 PolarHBondContact O-N 3.06Å; S210-M212 WeakPolarHBondContact OG-CB 3.12Å; S210-M212 PolarHBondContact OG-N 2.95Å; S210-H213 VanDerWaalsContact O-CB 3.32Å; S210-H213 WeakPolarHBondContact O-CB 3.36Å; S210-H213 PolarHBondContact O-N 2.66Å; S210-D249 WeakPolarHBondContact CA-OD2 3.44Å; S210-D249 WeakPolarHBondContact CB-OD1 3.49Å; S210-D249 PolarHBondContact OG-OD1 2.6Å
211L97.8Very high95.4Very high0 Ų035.1 Ų35.10%018%0.178CC..THydrogen-bonded Turntrans-60.7-23.2171.1-17766.4000111.3A151 E154 H155 L158 E209 H213 R242 F245 D249A151-L211 HydrophobicContact CB-CD1 3.86Å; E154-L211 HydrophobicContact CB-CD2 3.6Å; H155-L211 HydrophobicContact CB-CD2 4.28Å; H155-L211 HydrophobicContact CB-CG 4.18Å; H155-L211 PolarHBondContact ND1-O 3.42Å; L158-L211 HydrophobicContact CD1-CD2 4.26Å; E209-L211 PolarHBondContact O-N 3.45Å; L211-H213 VanDerWaalsContact C-N 3.31Å; L211-R242 PolarHBondContact O-NH1 3.01Å; L211-F245 HydrophobicContact CD2-CD1 3.94Å; L211-F245 HydrophobicContact CD2-CE1 4.03Å; L211-D249 WeakPolarHBondContact CB-OD2 3.34Å; L211-D249 PolarHBondContact N-OD2 2.95Å
212M98.1Very high95.9Very high2 Ų236.4 Ų36.41%0.0118%0.184CC..THydrogen-bonded Turntrans-87.89.2176.5-51.6-51.7-64.800113.2H155 L158 H159 F163 H165 E166 S210H155-M212 HydrophobicContact CB-SD 4.38Å; H155-M212 PolarHBondContact ND1-SD 3.39Å; L158-M212 HydrophobicContact CB-CE 4.18Å; L158-M212 HydrophobicContact CB-CG 4.49Å; L158-M212 HydrophobicContact CB-SD 3.55Å; L158-M212 VanDerWaalsContact CB-SD 3.55Å; L158-M212 HydrophobicContact CD1-CG 3.87Å; L158-M212 HydrophobicContact CD1-SD 3.49Å; L158-M212 WeakPolarHBondContact CD1-SD 3.43Å; L158-M212 HydrophobicContact CG-SD 4.19Å; H159-M212 WeakPolarHBondContact CE1-CE 3.32Å; H159-M212 WeakPolarHBondContact ND1-CE 3.31Å; H159-M212 WeakPolarHBondContact NE2-CE 3.45Å; F163-M212 HydrophobicContact CB-CE 4.36Å; F163-M212 HydrophobicContact CB-CG 4.45Å; H165-M212 CarbonylContact C-O 3.56Å; H165-M212 WeakPolarHBondContact CA-O 3.39Å; H165-M212 WeakPolarHBondContact CB-O 3.33Å; H165-M212 PolarHBondContact CD2-O 2.89Å; H165-M212 VanDerWaalsContact CD2-O 3.26Å; E166-M212 PolarHBondContact N-O 2.67Å; S210-M212 PolarHBondContact O-N 3.06Å; S210-M212 WeakPolarHBondContact OG-CB 3.12Å; S210-M212 PolarHBondContact OG-N 2.95Å
213H98.4Very high95.8Very high0 Ų038.3 Ų38.30%021%0.206CC..SBendtrans-92140176-158.9-62.6000111.3E166 Y206 S210 L211 G240 R242E166-H213 HydrophobicContact CB-CB 4.08Å; Y206-H213 AromaticContact CE1-CD2 3.84Å; Y206-H213 AromaticContact CE1-NE2 3.63Å; Y206-H213 AromaticContact CZ-CD2 3.87Å; Y206-H213 AromaticContact CZ-NE2 3.58Å; Y206-H213 PolarHBondContact OH-CD2 3.39Å; Y206-H213 VanDerWaalsContact OH-CD2 3.3Å; Y206-H213 PolarHBondContact OH-NE2 2.93Å; S210-H213 VanDerWaalsContact O-CB 3.32Å; S210-H213 WeakPolarHBondContact O-CB 3.36Å; S210-H213 PolarHBondContact O-N 2.66Å; L211-H213 VanDerWaalsContact C-N 3.31Å; H213-G240 WeakPolarHBondContact O-CA 3.43Å; H213-R242 PolarHBondContact O-NH1 2.89Å; H213-R242 PolarHBondContact O-NH2 3.35Å
214Y98.1Very high95.8Very high4 Ų436.6 Ų36.62%0.01621%0.205CC..PPolyproline II helixtrans-64.7153.3169.6-81.44.4000113.4Q56 H165 Q167 N190 F191 F219 G240Q56-Y214 WeakPolarHBondContact CA-OH 3.45Å; Q56-Y214 PolarHBondContact O-OH 3.23Å; H165-Y214 AromaticContact CD2-CD1 3.97Å; H165-Y214 AromaticContact CD2-CE1 3.67Å; H165-Y214 AromaticContact CE1-CE1 3.68Å; H165-Y214 AromaticContact CG-CE1 3.98Å; H165-Y214 AromaticContact NE2-CE1 3.44Å; H165-Y214 WeakPolarHBondContact NE2-CE1 3.37Å; Q167-Y214 VanDerWaalsContact CD-CG 3.41Å; Q167-Y214 HydrophobicContact CG-CD2 4.08Å; Q167-Y214 HydrophobicContact CG-CG 4.16Å; Q167-Y214 VanDerWaalsContact NE2-CE1 3.27Å; Q167-Y214 VanDerWaalsContact NE2-CE2 3.31Å; Q167-Y214 VanDerWaalsContact NE2-CZ 3.32Å; N190-Y214 HydrophobicContact CB-CE2 4.4Å; F191-Y214 HydrophobicContact CE1-CD2 4.01Å; F191-Y214 HydrophobicContact CE1-CE2 4.4Å; F191-Y214 HydrophobicContact CZ-CD2 4.2Å; F191-Y214 HydrophobicContact CZ-CE2 4.33Å; Y214-F219 HydrophobicContact CE2-CD2 4.1Å; Y214-F219 AromaticContact CE2-CE2 3.78Å; Y214-F219 HydrophobicContact CE2-CE2 3.78Å; Y214-F219 AromaticContact CZ-CE2 3.84Å; Y214-G240 PolarHBondContact O-N 3.07Å
215Q95Very high95.8Very high54 Ų5438.6 Ų38.625%0.25222%0.217SC..PPolyproline II helixtrans-75.2159.6168.6-75.9-171.5-2.300111.8F217 S218 I228 G240Q215-F217 PolarHBondContact O-N 2.66Å; Q215-F217 VanDerWaalsContact O-N 3.09Å; Q215-S218 PolarHBondContact N-OG 2.93Å; Q215-S218 PolarHBondContact O-N 2.91Å; Q215-S218 PolarHBondContact O-OG 3.23Å; Q215-I228 WeakPolarHBondContact O-CG2 3.34Å; Q215-G240 VanDerWaalsContact CG-O 3.26Å; Q215-G240 WeakPolarHBondContact CG-O 3.29Å; Q215-G240 PolarHBondContact NE2-O 2.89Å
216P95.6Very high95.8Very high19 Ų1936.3 Ų36.312%0.12320%0.202CC..THydrogen-bonded Turntrans-54-31.4178.6-26.434.3000114.6P226 T227 I228 N236 I239P216-P226 HydrophobicContact CB-CB 3.94Å; P216-P226 CarbonylContact O-C 3.41Å; P216-P226 WeakPolarHBondContact O-CA 3.42Å; P216-P226 WeakPolarHBondContact O-CB 3.32Å; P216-T227 PolarHBondContact O-N 3.37Å; P216-T227 PolarHBondContact O-OG1 2.83Å; P216-I228 WeakPolarHBondContact CA-O 3.23Å; P216-I228 PolarHBondContact O-N 2.78Å; P216-N236 VanDerWaalsContact CG-O 3.25Å; P216-N236 WeakPolarHBondContact CG-O 2.88Å; P216-I239 HydrophobicContact CG-CD1 3.94Å; P216-I239 HydrophobicContact CG-CG1 3.86Å
217F95.2Very high95.8Very high93 Ų9335.8 Ų35.841%0.40820%0.2SC..THydrogen-bonded Turntrans-103.35.7-171.2-59.9-76.6000114.2Q215 F219 N220 P226Q215-F217 PolarHBondContact O-N 2.66Å; Q215-F217 VanDerWaalsContact O-N 3.09Å; F217-F219 PolarHBondContact O-N 2.89Å; F217-N220 WeakPolarHBondContact O-CB 3.38Å; F217-N220 PolarHBondContact O-N 2.82Å; F217-N220 PolarHBondContact O-OD1 3.2Å; F217-P226 HydrophobicContact CD1-CB 4.27Å; F217-P226 HydrophobicContact CE1-CB 4.16Å
218S95.6Very high95.8Very high2 Ų235.3 Ų35.31%0.01420%0.198CC..THydrogen-bonded Turntrans-55.2128.1-179.6-60.90000111S44 F191 Q215 N220 T227S44-S218 PolarHBondContact OG-OG 3.28Å; F191-S218 WeakPolarHBondContact CZ-O 3.29Å; Q215-S218 PolarHBondContact N-OG 2.93Å; Q215-S218 PolarHBondContact O-N 2.91Å; Q215-S218 PolarHBondContact O-OG 3.23Å; S218-N220 VanDerWaalsContact C-N 3.28Å; S218-N220 PolarHBondContact O-N 2.79Å; S218-T227 WeakPolarHBondContact O-CB 3.35Å; S218-T227 WeakPolarHBondContact O-CG2 3.08Å; S218-T227 PolarHBondContact O-OG1 3.39Å
219F96.1Very high95.8Very high7 Ų735.2 Ų35.23%0.03120%0.199CC..THydrogen-bonded Turntrans55.331-179.9-51.1-76.2000115.9I183 L184 Y187 N190 F191 Y214 F217I183-F219 HydrophobicContact CG2-CB 4.4Å; L184-F219 WeakPolarHBondContact CG-O 3.47Å; L184-F219 PolarHBondContact N-O 3.24Å; Y187-F219 AromaticContact CD1-CD1 3.54Å; Y187-F219 HydrophobicContact CD1-CD1 3.54Å; Y187-F219 AromaticContact CD1-CE1 3.75Å; Y187-F219 HydrophobicContact CD1-CE1 3.75Å; Y187-F219 HydrophobicContact CD1-CG 4.39Å; Y187-F219 HydrophobicContact CE1-CD1 4.15Å; Y187-F219 HydrophobicContact CE1-CE1 4.09Å; Y187-F219 HydrophobicContact CG-CD1 4.04Å; N190-F219 HydrophobicContact CB-CD2 4.34Å; N190-F219 HydrophobicContact CB-CE2 4.15Å; N190-F219 WeakPolarHBondContact ND2-CZ 3.39Å; F191-F219 HydrophobicContact CE2-CB 4.09Å; F191-F219 AromaticContact CE2-CD2 3.93Å; F191-F219 HydrophobicContact CE2-CD2 3.93Å; F191-F219 HydrophobicContact CE2-CG 4.41Å; F191-F219 HydrophobicContact CZ-CB 4.4Å; F191-F219 HydrophobicContact CZ-CD2 4.12Å; Y214-F219 HydrophobicContact CE2-CD2 4.1Å; Y214-F219 AromaticContact CE2-CE2 3.78Å; Y214-F219 HydrophobicContact CE2-CE2 3.78Å; Y214-F219 AromaticContact CZ-CE2 3.84Å; F217-F219 PolarHBondContact O-N 2.89Å
220N95.3Very high95.9Very high32 Ų3232.4 Ų32.417%0.17119%0.187CC..BIsolated β-bridgetrans-74.7144.5178.766.7-10.3000113.7E182 L184 F217 S218 N222 A223 V225 T227E182-N220 CarbonylContact O-C 3.54Å; E182-N220 WeakPolarHBondContact O-CA 3.37Å; L184-N220 WeakPolarHBondContact CG-O 3.03Å; F217-N220 WeakPolarHBondContact O-CB 3.38Å; F217-N220 PolarHBondContact O-N 2.82Å; F217-N220 PolarHBondContact O-OD1 3.2Å; S218-N220 VanDerWaalsContact C-N 3.28Å; S218-N220 PolarHBondContact O-N 2.79Å; N220-N222 PolarHBondContact ND2-O 3.47Å; N220-A223 VanDerWaalsContact ND2-CA 3.32Å; N220-A223 WeakPolarHBondContact ND2-CA 3.36Å; N220-V225 WeakPolarHBondContact CB-O 3.39Å; N220-V225 PolarHBondContact ND2-O 3.03Å; N220-V225 VanDerWaalsContact ND2-O 3.17Å; N220-T227 HydrophobicContact CB-CG2 3.77Å
221K94.3Very high95.9Very high103 Ų10337 Ų3745%0.44821%0.207SC..SBendtrans-71.3-38.6170.7-74.5167.7168.6133.90111.8D181 E182 I183 L184D181-K221 WeakPolarHBondContact O-CD 3.47Å; D181-K221 PolarHBondContact O-NZ 2.8Å; E182-K221 WeakPolarHBondContact O-CG 3.4Å; E182-K221 PolarHBondContact O-N 2.99Å; I183-K221 WeakPolarHBondContact O-CD 3.36Å; I183-K221 WeakPolarHBondContact O-CE 3.45Å; I183-K221 PolarHBondContact O-NZ 2.88Å; L184-K221 HydrophobicContact CD2-CG 4.09Å; L184-K221 HydrophobicContact CG-CG 4.46Å
222N92.1Very high95.9Very high79 Ų7941 Ų4142%0.42223%0.227SC..SBendtrans-118.6118.1-177.8-179.8-17.4000108.9N220 S224 V225N220-N222 PolarHBondContact ND2-O 3.47Å; N222-S224 PolarHBondContact O-N 3.47Å; N222-S224 PolarHBondContact OD1-N 2.96Å; N222-S224 VanDerWaalsContact OD1-N 3.09Å; N222-V225 HydrophobicContact CB-CB 4.23Å; N222-V225 HydrophobicContact CB-CG2 4.03Å; N222-V225 PolarHBondContact O-N 3.21Å
223A88.1Confident95.7Very high81 Ų8145 Ų4567%0.66925%0.254SS*.THydrogen-bonded Turntrans-52.3-22.1-176.700000114.7N220N220-A223 VanDerWaalsContact ND2-CA 3.32Å; N220-A223 WeakPolarHBondContact ND2-CA 3.36Å
224S91.6Very high95.3Very high101 Ų10151.1 Ų51.171%0.70628%0.282SS*.THydrogen-bonded Turntrans-100-1.1179.9-54.60000114.7N222N222-S224 PolarHBondContact O-N 3.47Å; N222-S224 PolarHBondContact OD1-N 2.96Å; N222-S224 VanDerWaalsContact OD1-N 3.09Å
225V95.2Very high95.1Very high47 Ų4754 Ų5429%0.28530%0.295SS..SBendtrans-116.7126.4-178.3-173.40000109.2E182 N220 N222E182-V225 HydrophobicContact CB-CG1 4.29Å; E182-V225 HydrophobicContact CG-CG1 3.69Å; N220-V225 WeakPolarHBondContact CB-O 3.39Å; N220-V225 PolarHBondContact ND2-O 3.03Å; N220-V225 VanDerWaalsContact ND2-O 3.17Å; N222-V225 HydrophobicContact CB-CB 4.23Å; N222-V225 HydrophobicContact CB-CG2 4.03Å; N222-V225 PolarHBondContact O-N 3.21Å
226P97Very high95Very high32 Ų3253.7 Ų53.721%0.20830%0.295CS..  trans-75.8147179.231.4-35000111.6P216 F217 T229P216-P226 HydrophobicContact CB-CB 3.94Å; P216-P226 CarbonylContact O-C 3.41Å; P216-P226 WeakPolarHBondContact O-CA 3.42Å; P216-P226 WeakPolarHBondContact O-CB 3.32Å; F217-P226 HydrophobicContact CD1-CB 4.27Å; F217-P226 HydrophobicContact CE1-CB 4.16Å; P226-T229 HydrophobicContact CB-CG2 4.04Å; P226-T229 HydrophobicContact CG-CG2 3.57Å
227T98.1Very high94.6Very high0 Ų055.1 Ų55.10%031%0.305CS..SBendtrans-86.7-24.7169.8480000112.1W179 E182 I183 F191 P216 S218 N220W179-T227 PolarHBondContact N-O 2.87Å; E182-T227 HydrophobicContact CB-CG2 4.49Å; I183-T227 HydrophobicContact CB-CG2 4.34Å; I183-T227 HydrophobicContact CG1-CG2 3.76Å; F191-T227 HydrophobicContact CZ-CG2 4.47Å; P216-T227 PolarHBondContact O-N 3.37Å; P216-T227 PolarHBondContact O-OG1 2.83Å; S218-T227 WeakPolarHBondContact O-CB 3.35Å; S218-T227 WeakPolarHBondContact O-CG2 3.08Å; S218-T227 PolarHBondContact O-OG1 3.39Å; N220-T227 HydrophobicContact CB-CG2 3.77Å
228I98.2Very high94.5Very high0 Ų051.7 Ų51.70%029%0.291CS..EExtended strand (participates in β ladder)trans-132.1133.6178.4-177167.1000110.1Q167 V176 N177 I178 Q215 P216 I239Q167-I228 HydrophobicContact CB-CD1 3.75Å; Q167-I228 HydrophobicContact CG-CD1 4.24Å; V176-I228 HydrophobicContact CB-CD1 4.11Å; V176-I228 HydrophobicContact CB-CG1 4.01Å; V176-I228 HydrophobicContact CG1-CD1 4.22Å; V176-I228 HydrophobicContact CG1-CG1 4.32Å; V176-I228 HydrophobicContact CG2-CD1 3.95Å; V176-I228 HydrophobicContact CG2-CG1 4.27Å; N177-I228 WeakPolarHBondContact O-CA 3.5Å; I178-I228 HydrophobicContact CD1-CB 4.08Å; I178-I228 HydrophobicContact CD1-CD1 3.72Å; I178-I228 HydrophobicContact CD1-CG1 3.77Å; Q215-I228 WeakPolarHBondContact O-CG2 3.34Å; P216-I228 WeakPolarHBondContact CA-O 3.23Å; P216-I228 PolarHBondContact O-N 2.78Å; I228-I239 HydrophobicContact CG1-CD1 4.36Å; I228-I239 HydrophobicContact CG2-CD1 4.15Å
229T98.1Very high94.5Very high20 Ų2051.9 Ų51.912%0.12329%0.292CS..EExtended strand (participates in β ladder)trans-133.1141173.6540000109.8V176 N177 W179 P226 N236V176-T229 CarbonylContact C-O 3.59Å; V176-T229 VanDerWaalsContact CA-O 3.3Å; V176-T229 WeakPolarHBondContact CA-O 3.39Å; V176-T229 WeakPolarHBondContact CB-O 3.44Å; N177-T229 PolarHBondContact N-O 2.88Å; N177-T229 PolarHBondContact O-N 2.79Å; W179-T229 PolarHBondContact NE1-OG1 2.88Å; P226-T229 HydrophobicContact CB-CG2 4.04Å; P226-T229 HydrophobicContact CG-CG2 3.57Å; T229-N236 WeakPolarHBondContact CA-OD1 3.38Å; T229-N236 WeakPolarHBondContact CB-OD1 3.45Å
230A98Very high94.5Very high5 Ų551.7 Ų51.74%0.04129%0.292CS..EExtended strand (participates in β ladder)trans-66.4141.4169.100000110.4Y208 I232 F235 N236Y208-A230 HydrophobicContact CD1-CB 4.38Å; Y208-A230 HydrophobicContact CE1-CB 3.91Å; A230-I232 VanDerWaalsContact CB-O 3.3Å; A230-I232 WeakPolarHBondContact CB-O 3.27Å; A230-I232 PolarHBondContact O-N 2.95Å; A230-F235 HydrophobicContact CB-CB 3.7Å; A230-N236 PolarHBondContact N-OD1 2.59Å
231K98.3Very high94.4Very high97 Ų9750.8 Ų50.842%0.42229%0.287SS..SBendtrans-65.2-29.1173.8-78.4-179.9167.5-174.40112.4D173 D174 Y175 N177D173-K231 WeakPolarHBondContact O-CE 3.41Å; D173-K231 PolarHBondContact O-NZ 2.92Å; D174-K231 WeakPolarHBondContact O-CD 3.26Å; Y175-K231 PolarHBondContact O-N 2.57Å; N177-K231 VanDerWaalsContact OD1-CE 3.23Å; N177-K231 WeakPolarHBondContact OD1-CE 3.23Å
232I97.3Very high94.4Very high83 Ų8347.6 Ų47.643%0.42627%0.272SS..SBendtrans-97.1107.5169.9-64.3167.3000106.8A230 E234 F235A230-I232 VanDerWaalsContact CB-O 3.3Å; A230-I232 WeakPolarHBondContact CB-O 3.27Å; A230-I232 PolarHBondContact O-N 2.95Å; I232-E234 HydrophobicContact CG2-CB 4.48Å; I232-E234 WeakPolarHBondContact CG2-OE2 3.48Å; I232-E234 PolarHBondContact O-N 2.88Å; I232-F235 HydrophobicContact CB-CD2 3.68Å; I232-F235 HydrophobicContact CB-CE2 3.92Å; I232-F235 HydrophobicContact CD1-CD2 4.5Å; I232-F235 HydrophobicContact CD1-CE2 4.02Å; I232-F235 HydrophobicContact CG2-CD2 3.61Å; I232-F235 HydrophobicContact CG2-CE2 3.59Å; I232-F235 PolarHBondContact O-N 3.32Å; I232-F235 VanDerWaalsContact O-N 3.12Å
233P93.5Very high94.5Very high87 Ų8744.7 Ų44.757%0.56526%0.256SS*.G310 helixtrans-57.7-26.5-166.6-28.636.4000115.7F235 N236P233-F235 PolarHBondContact O-N 3.42Å; P233-N236 WeakPolarHBondContact CA-ND2 3.3Å; P233-N236 WeakPolarHBondContact O-CB 3.42Å; P233-N236 PolarHBondContact O-N 3.39Å; P233-N236 VanDerWaalsContact O-N 3.14Å; P233-N236 PolarHBondContact O-ND2 3.05Å; P233-N236 VanDerWaalsContact O-ND2 3.11Å
234E90.3Very high94.9Very high127 Ų12741 Ų4159%0.59323%0.226SC*.G310 helixtrans-61-27.6180-64.877.5-173.200112.7I232 R578I232-E234 HydrophobicContact CG2-CB 4.48Å; I232-E234 WeakPolarHBondContact CG2-OE2 3.48Å; I232-E234 PolarHBondContact O-N 2.88Å; E234-R578 PolarHBondContact O-NH2 2.82Å
235F94.1Very high95.2Very high65 Ų6536.3 Ų36.329%0.28519%0.192SC..G310 helixtrans-84.9-5.7178.6-60.6-72.3000114.2Y208 A230 I232 P233 S237 I238 I239Y208-F235 HydrophobicContact CD1-CB 3.85Å; Y208-F235 HydrophobicContact CD1-CG 4.24Å; Y208-F235 HydrophobicContact CD2-CB 4.18Å; Y208-F235 AromaticContact CD2-CD1 3.68Å; Y208-F235 HydrophobicContact CD2-CD1 3.68Å; Y208-F235 AromaticContact CD2-CD2 3.86Å; Y208-F235 HydrophobicContact CD2-CD2 3.86Å; Y208-F235 HydrophobicContact CD2-CE1 4.01Å; Y208-F235 HydrophobicContact CD2-CE2 4.14Å; Y208-F235 AromaticContact CD2-CG 3.65Å; Y208-F235 HydrophobicContact CD2-CG 3.65Å; Y208-F235 HydrophobicContact CD2-CZ 4.23Å; Y208-F235 HydrophobicContact CE1-CB 4.21Å; Y208-F235 HydrophobicContact CE1-CG 4.49Å; Y208-F235 HydrophobicContact CE2-CD1 4.34Å; Y208-F235 AromaticContact CE2-CD2 3.67Å; Y208-F235 HydrophobicContact CE2-CD2 3.67Å; Y208-F235 AromaticContact CE2-CE2 3.88Å; Y208-F235 HydrophobicContact CE2-CE2 3.88Å; Y208-F235 AromaticContact CE2-CG 3.94Å; Y208-F235 HydrophobicContact CE2-CG 3.94Å; Y208-F235 HydrophobicContact CE2-CZ 4.34Å; Y208-F235 HydrophobicContact CG-CB 3.82Å; Y208-F235 AromaticContact CG-CD1 3.91Å; Y208-F235 HydrophobicContact CG-CD1 3.91Å; Y208-F235 HydrophobicContact CG-CD2 4.36Å; Y208-F235 AromaticContact CG-CG 3.79Å; Y208-F235 HydrophobicContact CG-CG 3.79Å; A230-F235 HydrophobicContact CB-CB 3.7Å; I232-F235 HydrophobicContact CB-CD2 3.68Å; I232-F235 HydrophobicContact CB-CE2 3.92Å; I232-F235 HydrophobicContact CD1-CD2 4.5Å; I232-F235 HydrophobicContact CD1-CE2 4.02Å; I232-F235 HydrophobicContact CG2-CD2 3.61Å; I232-F235 HydrophobicContact CG2-CE2 3.59Å; I232-F235 PolarHBondContact O-N 3.32Å; I232-F235 VanDerWaalsContact O-N 3.12Å; P233-F235 PolarHBondContact O-N 3.42Å; F235-S237 PolarHBondContact O-N 3.47Å; F235-I238 HydrophobicContact CB-CB 4.49Å; F235-I238 HydrophobicContact CD1-CB 4.43Å; F235-I238 HydrophobicContact CD1-CD1 3.45Å; F235-I238 VanDerWaalsContact CD1-CD1 3.45Å; F235-I238 HydrophobicContact CD1-CG1 4.38Å; F235-I238 HydrophobicContact CE1-CD1 4.03Å; F235-I238 HydrophobicContact CG-CD1 4.37Å; F235-I238 WeakPolarHBondContact O-CB 3.43Å; F235-I238 PolarHBondContact O-N 2.82Å; F235-I239 PolarHBondContact O-N 3.27Å; F235-I239 VanDerWaalsContact O-N 3.17Å
236N92.6Very high95.3Very high47 Ų4734.1 Ų34.125%0.25118%0.179SC..G310 helixtrans-59.6-32.4178.3-78-44000113.3P216 T229 A230 P233 I238P216-N236 VanDerWaalsContact CG-O 3.25Å; P216-N236 WeakPolarHBondContact CG-O 2.88Å; T229-N236 WeakPolarHBondContact CA-OD1 3.38Å; T229-N236 WeakPolarHBondContact CB-OD1 3.45Å; A230-N236 PolarHBondContact N-OD1 2.59Å; P233-N236 WeakPolarHBondContact CA-ND2 3.3Å; P233-N236 WeakPolarHBondContact O-CB 3.42Å; P233-N236 PolarHBondContact O-N 3.39Å; P233-N236 VanDerWaalsContact O-N 3.14Å; P233-N236 PolarHBondContact O-ND2 3.05Å; P233-N236 VanDerWaalsContact O-ND2 3.11Å; N236-I238 VanDerWaalsContact C-N 3.34Å
237S88.4Confident95.3Very high49 Ų4935.2 Ų35.234%0.34319%0.19SC..G310 helixtrans-93.99.9176.157.40000113.3F235 Q574 R578F235-S237 PolarHBondContact O-N 3.47Å; S237-Q574 PolarHBondContact OG-NE2 3.02Å; S237-R578 PolarHBondContact O-NH1 2.96Å; S237-R578 PolarHBondContact OG-NH1 3.08Å; S237-R578 PolarHBondContact OG-NH2 2.9Å
238I92.4Very high95.3Very high21 Ų2136.7 Ų36.711%0.10820%0.198CC..THydrogen-bonded Turntrans-103.2-44.2177.8-64.6179.5000109.7E209 F235 N236 G240 Q241E209-I238 HydrophobicContact CB-CG2 4.31Å; E209-I238 HydrophobicContact CG-CG2 3.31Å; F235-I238 HydrophobicContact CB-CB 4.49Å; F235-I238 HydrophobicContact CD1-CB 4.43Å; F235-I238 HydrophobicContact CD1-CD1 3.45Å; F235-I238 VanDerWaalsContact CD1-CD1 3.45Å; F235-I238 HydrophobicContact CD1-CG1 4.38Å; F235-I238 HydrophobicContact CE1-CD1 4.03Å; F235-I238 HydrophobicContact CG-CD1 4.37Å; F235-I238 WeakPolarHBondContact O-CB 3.43Å; F235-I238 PolarHBondContact O-N 2.82Å; N236-I238 VanDerWaalsContact C-N 3.34Å; I238-G240 PolarHBondContact O-N 3.16Å; I238-Q241 PolarHBondContact O-N 2.82Å
239I95.9Very high95.3Very high6 Ų636.7 Ų36.73%0.03120%0.198CC..THydrogen-bonded Turntrans-58.1137.2-179.658.7168.5000112.5Y208 P216 I228 F235Y208-I239 HydrophobicContact CD1-CG2 3.68Å; Y208-I239 HydrophobicContact CG-CG2 4.34Å; Y208-I239 VanDerWaalsContact O-CA 3.32Å; Y208-I239 WeakPolarHBondContact O-CA 3.33Å; P216-I239 HydrophobicContact CG-CD1 3.94Å; P216-I239 HydrophobicContact CG-CG1 3.86Å; I228-I239 HydrophobicContact CG1-CD1 4.36Å; I228-I239 HydrophobicContact CG2-CD1 4.15Å; F235-I239 PolarHBondContact O-N 3.27Å; F235-I239 VanDerWaalsContact O-N 3.17Å
240G94.9Very high95.3Very high3 Ų336.1 Ų36.13%0.03119%0.194CC..THydrogen-bonded Turntrans74.227179.700000114.8H213 Y214 Q215 I238H213-G240 WeakPolarHBondContact O-CA 3.43Å; Y214-G240 PolarHBondContact O-N 3.07Å; Q215-G240 VanDerWaalsContact CG-O 3.26Å; Q215-G240 WeakPolarHBondContact CG-O 3.29Å; Q215-G240 PolarHBondContact NE2-O 2.89Å; I238-G240 PolarHBondContact O-N 3.16Å
241Q94.1Very high95.2Very high14 Ų1439.6 Ų39.67%0.06521%0.21CC..  trans-56.5147.1168.669.680.51900111.5E209 I238 D244 M521E209-Q241 VanDerWaalsContact O-CG 3.25Å; E209-Q241 WeakPolarHBondContact O-CG 3.29Å; E209-Q241 PolarHBondContact O-NE2 2.65Å; I238-Q241 PolarHBondContact O-N 2.82Å; Q241-D244 PolarHBondContact NE2-O 3.4Å; Q241-M521 VanDerWaalsContact CD-CE 3.49Å; Q241-M521 HydrophobicContact CG-CE 4.3Å; Q241-M521 VanDerWaalsContact NE2-CE 3.32Å
242R93.6Very high95Very high35 Ų3535.5 Ų35.513%0.13219%0.191CC..  trans-130.944.6179.4-61.2-65.9176.8-103.73.9111.3D42 A151 L211 H213D42-R242 VanDerWaalsContact CG-NH2 3.29Å; D42-R242 IonicContact OD1-CZ 3.52Å; D42-R242 IonicContact OD1-NE 3.09Å; D42-R242 PolarHBondContact OD1-NE 3.01Å; D42-R242 IonicContact OD1-NH2 2.72Å; D42-R242 PolarHBondContact OD1-NH2 3.14Å; D42-R242 IonicContact OD2-NH2 2.79Å; D42-R242 PolarHBondContact OD2-NH2 3.12Å; D42-R242 VanDerWaalsContact OD2-NH2 3.15Å; A151-R242 HydrophobicContact CB-CB 4.05Å; A151-R242 WeakPolarHBondContact CB-O 3.46Å; L211-R242 PolarHBondContact O-NH1 3.01Å; H213-R242 PolarHBondContact O-NH1 2.89Å; H213-R242 PolarHBondContact O-NH2 3.35Å
243L94.6Very high95Very high18 Ų1831.5 Ų31.59%0.09417%0.171CC..SBendtrans-92.9-63.3176.9-60.5171.8000110.5K150 M521 M575 F581K150-L243 VanDerWaalsContact CE-O 3.26Å; K150-L243 WeakPolarHBondContact CE-O 3.36Å; K150-L243 PolarHBondContact NZ-O 2.84Å; L243-M521 HydrophobicContact CB-CB 4.31Å; L243-M575 HydrophobicContact CD1-CE 4.35Å; L243-M575 HydrophobicContact CD1-CG 4.2Å; L243-M575 HydrophobicContact CD1-SD 4.07Å; L243-F581 HydrophobicContact CD1-CE2 4.32Å; L243-F581 HydrophobicContact CD1-CZ 4.08Å; L243-F581 HydrophobicContact CD2-CZ 4.48Å
244D96.8Very high95.1Very high5 Ų529.2 Ų29.23%0.02715%0.154CC..SBendtrans-166.9-176.9-173.1-149.1-56.8000110.1K105 K150 Q241 M521K105-D244 IonicContact NZ-OD1 2.88Å; K105-D244 PolarHBondContact NZ-OD1 2.03Å; K105-D244 IonicContact NZ-OD2 3.23Å; K105-D244 PolarHBondContact NZ-OD2 3.39Å; K150-D244 IonicContact NZ-OD1 2.85Å; K150-D244 IonicContact NZ-OD2 3.61Å; K150-D244 PolarHBondContact NZ-OD2 3.26Å; Q241-D244 PolarHBondContact NE2-O 3.4Å; D244-M521 HydrophobicContact CB-CB 4.1Å; D244-M521 HydrophobicContact CB-CG 4.22Å; D244-M521 WeakPolarHBondContact O-CE 3.09Å
245F98.2Very high95.3Very high2 Ų228 Ų281%0.00914%0.144CC..  trans-58.1136.9167.7-51.1-66.8000111.4M101 F102 K105 E154 L158 L211 D249 L250 M521M101-F245 HydrophobicContact CB-CE2 4.18Å; F102-F245 HydrophobicContact CD1-CZ 4.03Å; F102-F245 HydrophobicContact CD2-CZ 4.04Å; F102-F245 AromaticContact CE1-CE1 3.96Å; F102-F245 HydrophobicContact CE1-CE1 3.96Å; F102-F245 HydrophobicContact CE1-CE2 4.43Å; F102-F245 AromaticContact CE1-CZ 3.56Å; F102-F245 HydrophobicContact CE1-CZ 3.56Å; F102-F245 HydrophobicContact CE2-CE1 4.36Å; F102-F245 HydrophobicContact CE2-CE2 4.49Å; F102-F245 AromaticContact CE2-CZ 3.57Å; F102-F245 HydrophobicContact CE2-CZ 3.57Å; F102-F245 HydrophobicContact CG-CZ 4.25Å; F102-F245 AromaticContact CZ-CE1 3.72Å; F102-F245 HydrophobicContact CZ-CE1 3.72Å; F102-F245 HydrophobicContact CZ-CE2 4.43Å; F102-F245 AromaticContact CZ-CZ 3.31Å; F102-F245 HydrophobicContact CZ-CZ 3.31Å; K105-F245 HydrophobicContact CD-CD2 3.92Å; E154-F245 HydrophobicContact CB-CE1 3.73Å; E154-F245 HydrophobicContact CB-CE2 4.45Å; E154-F245 HydrophobicContact CB-CZ 3.62Å; E154-F245 HydrophobicContact CG-CE1 4.17Å; E154-F245 HydrophobicContact CG-CE2 3.99Å; E154-F245 HydrophobicContact CG-CZ 3.52Å; L158-F245 HydrophobicContact CD1-CD1 3.8Å; L158-F245 HydrophobicContact CD1-CE1 3.76Å; L158-F245 HydrophobicContact CD2-CE1 4.2Å; L158-F245 HydrophobicContact CG-CD1 4.35Å; L158-F245 HydrophobicContact CG-CE1 3.85Å; L211-F245 HydrophobicContact CD2-CD1 3.94Å; L211-F245 HydrophobicContact CD2-CE1 4.03Å; F245-D249 HydrophobicContact CB-CB 4.2Å; F245-L250 HydrophobicContact CB-CD1 4.29Å; F245-L250 HydrophobicContact CB-CD2 3.81Å; F245-L250 HydrophobicContact CB-CG 3.74Å; F245-L250 HydrophobicContact CD2-CD2 3.88Å; F245-L250 HydrophobicContact CG-CD2 3.86Å; F245-L250 HydrophobicContact CG-CG 4.36Å; F245-M521 WeakPolarHBondContact O-CG 3.38Å
246S97.7Very high95.2Very high1 Ų125 Ų251%0.00713%0.131CC..  trans-70.3167.1164.485.20000110.8D207 I248 D249 L250D207-S246 WeakPolarHBondContact OD2-CB 3.37Å; D207-S246 PolarHBondContact OD2-OG 3.05Å; S246-I248 PolarHBondContact O-N 2.87Å; S246-I248 PolarHBondContact OG-N 3.46Å; S246-I248 VanDerWaalsContact OG-N 3.12Å; S246-D249 PolarHBondContact N-OD2 2.95Å; S246-D249 PolarHBondContact O-N 3.11Å; S246-D249 VanDerWaalsContact OG-CG 3.29Å; S246-D249 PolarHBondContact OG-N 2.73Å; S246-D249 PolarHBondContact OG-OD2 2.87Å; S246-L250 WeakPolarHBondContact O-CG 3.4Å; S246-L250 PolarHBondContact O-N 2.81Å
247A96.8Very high95.3Very high54 Ų5424.2 Ų24.245%0.44613%0.125SC..Hα-helixtrans-60.6-33.9171.900000112.3E251A247-E251 WeakPolarHBondContact O-CB 3.19Å; A247-E251 PolarHBondContact O-N 3.03Å
248I97.5Very high95.6Very high32 Ų3228.1 Ų28.116%0.16414%0.142CC..Hα-helixtrans-78.9-35-178.2-64.5168.2000111.1T204 P205 D207 S246 L250 E251 R252T204-I248 HydrophobicContact CG2-CG2 4.22Å; T204-I248 VanDerWaalsContact OG1-CG2 3.31Å; T204-I248 WeakPolarHBondContact OG1-CG2 3.23Å; P205-I248 HydrophobicContact CG-CD1 3.95Å; D207-I248 HydrophobicContact CB-CB 4.04Å; D207-I248 HydrophobicContact CB-CD1 3.85Å; D207-I248 HydrophobicContact CB-CG2 4.02Å; S246-I248 PolarHBondContact O-N 2.87Å; S246-I248 PolarHBondContact OG-N 3.46Å; S246-I248 VanDerWaalsContact OG-N 3.12Å; I248-L250 VanDerWaalsContact C-N 3.3Å; I248-L250 PolarHBondContact O-N 3.1Å; I248-E251 PolarHBondContact O-N 3.48Å; I248-R252 HydrophobicContact CG2-CG 4.46Å; I248-R252 WeakPolarHBondContact O-CG 3.41Å; I248-R252 PolarHBondContact O-N 3.11Å
249D98.1Very high95.8Very high0 Ų028.3 Ų28.30%015%0.145CC..Hα-helixtrans-55.7-48.9170.8-68.5-34.6000110S210 L211 F245 S246 R252 L253S210-D249 WeakPolarHBondContact CA-OD2 3.44Å; S210-D249 WeakPolarHBondContact CB-OD1 3.49Å; S210-D249 PolarHBondContact OG-OD1 2.6Å; L211-D249 WeakPolarHBondContact CB-OD2 3.34Å; L211-D249 PolarHBondContact N-OD2 2.95Å; F245-D249 HydrophobicContact CB-CB 4.2Å; S246-D249 PolarHBondContact N-OD2 2.95Å; S246-D249 PolarHBondContact O-N 3.11Å; S246-D249 VanDerWaalsContact OG-CG 3.29Å; S246-D249 PolarHBondContact OG-N 2.73Å; S246-D249 PolarHBondContact OG-OD2 2.87Å; D249-R252 PolarHBondContact O-N 3.04Å; D249-L253 WeakPolarHBondContact O-CB 3.48Å; D249-L253 PolarHBondContact O-N 3.3Å
250L97.4Very high95.7Very high8 Ų834.3 Ų34.34%0.04218%0.182CC..Hα-helixtrans-66.2-40177.7-66.2174.5000112.6K105 F245 S246 I248 L253 N254 R518K105-L250 HydrophobicContact CB-CD1 3.94Å; K105-L250 HydrophobicContact CB-CD2 3.62Å; K105-L250 HydrophobicContact CB-CG 4.43Å; K105-L250 HydrophobicContact CD-CD1 4.03Å; K105-L250 HydrophobicContact CD-CD2 4.37Å; K105-L250 HydrophobicContact CG-CD1 4.3Å; F245-L250 HydrophobicContact CB-CD1 4.29Å; F245-L250 HydrophobicContact CB-CD2 3.81Å; F245-L250 HydrophobicContact CB-CG 3.74Å; F245-L250 HydrophobicContact CD2-CD2 3.88Å; F245-L250 HydrophobicContact CG-CD2 3.86Å; F245-L250 HydrophobicContact CG-CG 4.36Å; S246-L250 WeakPolarHBondContact O-CG 3.4Å; S246-L250 PolarHBondContact O-N 2.81Å; I248-L250 VanDerWaalsContact C-N 3.3Å; I248-L250 PolarHBondContact O-N 3.1Å; L250-L253 PolarHBondContact O-N 2.87Å; L250-N254 WeakPolarHBondContact O-CB 3.34Å; L250-N254 PolarHBondContact O-N 2.99Å; L250-N254 PolarHBondContact O-ND2 3.27Å; L250-R518 VanDerWaalsContact CD1-O 3.24Å; L250-R518 WeakPolarHBondContact CD1-O 3.13Å
251E96.6Very high95.4Very high77 Ų7738.3 Ų38.336%0.3621%0.206SC..Hα-helixtrans-60.2-47176.1177.2163.8-13900111.2T204 A247 I248 R255T204-E251 HydrophobicContact CG2-CG 4.18Å; A247-E251 WeakPolarHBondContact O-CB 3.19Å; A247-E251 PolarHBondContact O-N 3.03Å; I248-E251 PolarHBondContact O-N 3.48Å; E251-R255 HydrophobicContact CG-CG 4.46Å; E251-R255 VanDerWaalsContact O-CB 3.3Å; E251-R255 WeakPolarHBondContact O-CB 3.41Å; E251-R255 WeakPolarHBondContact O-CG 3.19Å; E251-R255 PolarHBondContact O-N 3.09Å; E251-R255 IonicContact OE1-CZ 2.57Å; E251-R255 VanDerWaalsContact OE1-CZ 3.24Å; E251-R255 IonicContact OE1-NE 3.09Å; E251-R255 PolarHBondContact OE1-NE 3.28Å; E251-R255 IonicContact OE1-NH2 2.87Å; E251-R255 PolarHBondContact OE1-NH2 2.81Å; E251-R255 IonicContact OE2-NH2 3.43Å
252R95.1Very high95.4Very high11 Ų1138.7 Ų38.74%0.04221%0.209CC..Hα-helixtrans-63.7-44.7176.1-72.3-168.5-170.4139.813.8111.7F163 E166 D201 L202 T204 P205 I248 D249 N254 R255 M256F163-R252 HydrophobicContact CE1-CB 3.77Å; F163-R252 HydrophobicContact CZ-CB 3.98Å; E166-R252 IonicContact OE1-CZ 3.76Å; E166-R252 IonicContact OE1-NH1 3.72Å; E166-R252 IonicContact OE1-NH2 3.73Å; E166-R252 PolarHBondContact OE1-NH2 3.44Å; E166-R252 IonicContact OE2-CZ 3.32Å; E166-R252 IonicContact OE2-NH1 3.75Å; E166-R252 PolarHBondContact OE2-NH1 2.77Å; E166-R252 IonicContact OE2-NH2 2.66Å; E166-R252 PolarHBondContact OE2-NH2 3.1Å; D201-R252 PolarHBondContact O-NE 2.85Å; D201-R252 VanDerWaalsContact O-NE 3.08Å; L202-R252 HydrophobicContact CB-CG 4.41Å; L202-R252 HydrophobicContact CD1-CB 4.17Å; L202-R252 WeakPolarHBondContact CD1-O 3.07Å; T204-R252 HydrophobicContact CG2-CG 3.75Å; T204-R252 VanDerWaalsContact OG1-CZ 3.25Å; T204-R252 PolarHBondContact OG1-NE 2.84Å; T204-R252 PolarHBondContact OG1-NH2 3.19Å; P205-R252 PolarHBondContact O-NH2 3.39Å; I248-R252 HydrophobicContact CG2-CG 4.46Å; I248-R252 WeakPolarHBondContact O-CG 3.41Å; I248-R252 PolarHBondContact O-N 3.11Å; D249-R252 PolarHBondContact O-N 3.04Å; R252-N254 PolarHBondContact O-N 3.25Å; R252-R255 PolarHBondContact O-N 3.44Å; R252-M256 VanDerWaalsContact O-CB 3.3Å; R252-M256 WeakPolarHBondContact O-CB 3.3Å; R252-M256 PolarHBondContact O-N 2.88Å
253L96Very high95.4Very high0 Ų039.6 Ų39.60%021%0.214CC..Hα-helixtrans-61.3-47.8-179.8176.864.2000111F102 V108 L158 L161 F163 D249 L250 M256 Y257F102-L253 HydrophobicContact CD1-CD2 4.09Å; F102-L253 HydrophobicContact CE1-CD2 3.97Å; V108-L253 HydrophobicContact CG2-CD1 4.09Å; V108-L253 HydrophobicContact CG2-CD2 4.02Å; V108-L253 HydrophobicContact CG2-CG 4.28Å; L158-L253 HydrophobicContact CD2-CD1 4.44Å; L158-L253 HydrophobicContact CD2-CD2 4.31Å; L161-L253 HydrophobicContact CB-CD1 4.42Å; L161-L253 HydrophobicContact CD1-CD1 3.85Å; F163-L253 HydrophobicContact CE2-CB 4.25Å; F163-L253 HydrophobicContact CE2-CD1 3.84Å; F163-L253 HydrophobicContact CZ-CB 3.89Å; F163-L253 HydrophobicContact CZ-CD1 4.34Å; D249-L253 WeakPolarHBondContact O-CB 3.48Å; D249-L253 PolarHBondContact O-N 3.3Å; L250-L253 PolarHBondContact O-N 2.87Å; L253-M256 PolarHBondContact O-N 3.24Å; L253-Y257 HydrophobicContact CD1-CD2 3.73Å; L253-Y257 HydrophobicContact CD1-CE2 3.92Å; L253-Y257 PolarHBondContact O-N 3.41Å
254N96.3Very high95.5Very high38 Ų3838.8 Ų38.820%0.20321%0.21CC..Hα-helixtrans-69-37-179.1-71.3-36.8000112K105 S106 L250 R252 N258 C259K105-N254 PolarHBondContact O-ND2 2.73Å; S106-N254 WeakPolarHBondContact CA-OD1 3.29Å; S106-N254 WeakPolarHBondContact CB-OD1 3.49Å; L250-N254 WeakPolarHBondContact O-CB 3.34Å; L250-N254 PolarHBondContact O-N 2.99Å; L250-N254 PolarHBondContact O-ND2 3.27Å; R252-N254 PolarHBondContact O-N 3.25Å; N254-N258 CarbonylContact O-C 3.53Å; N254-N258 WeakPolarHBondContact O-CA 3.24Å; N254-N258 PolarHBondContact O-N 2.97Å; N254-C259 HydrophobicContact CB-CB 3.85Å; N254-C259 PolarHBondContact O-N 2.55Å; N254-C259 WeakPolarHBondContact OD1-CB 3.41Å; N254-C259 PolarHBondContact OD1-SG 3.48Å
255R94.6Very high95.5Very high101 Ų10139.9 Ų39.938%0.38122%0.216SC..Hα-helixtrans-63.9-42.1171-75.6173.2-176.3-170.72.4111.4L202 N203 E251 R252 Y257 N258L202-R255 PolarHBondContact O-NH1 3.04Å; N203-R255 PolarHBondContact O-NH1 3.14Å; E251-R255 HydrophobicContact CG-CG 4.46Å; E251-R255 VanDerWaalsContact O-CB 3.3Å; E251-R255 WeakPolarHBondContact O-CB 3.41Å; E251-R255 WeakPolarHBondContact O-CG 3.19Å; E251-R255 PolarHBondContact O-N 3.09Å; E251-R255 IonicContact OE1-CZ 2.57Å; E251-R255 VanDerWaalsContact OE1-CZ 3.24Å; E251-R255 IonicContact OE1-NE 3.09Å; E251-R255 PolarHBondContact OE1-NE 3.28Å; E251-R255 IonicContact OE1-NH2 2.87Å; E251-R255 PolarHBondContact OE1-NH2 2.81Å; E251-R255 IonicContact OE2-NH2 3.43Å; R252-R255 PolarHBondContact O-N 3.44Å; R255-Y257 PolarHBondContact O-N 3.05Å; R255-N258 PolarHBondContact O-N 3.32Å; R255-N258 PolarHBondContact O-OD1 3.45Å
256M92.1Very high95.4Very high2 Ų241 Ų411%0.0122%0.222CC..Hα-helixtrans-64.1-41.5-178.7-175.4164.972.100112.4L68 R74 L161 F163 L202 R252 L253L68-M256 HydrophobicContact CD1-CE 3.81Å; L68-M256 HydrophobicContact CD1-SD 3.22Å; L68-M256 WeakPolarHBondContact CD1-SD 3.18Å; L68-M256 HydrophobicContact CG-SD 3.62Å; R74-M256 PolarHBondContact NH1-O 2.71Å; L161-M256 WeakPolarHBondContact O-CE 3.11Å; F163-M256 HydrophobicContact CD2-CE 4.03Å; F163-M256 HydrophobicContact CE2-CE 3.44Å; F163-M256 VanDerWaalsContact CE2-CE 3.44Å; F163-M256 HydrophobicContact CZ-CE 4.31Å; L202-M256 HydrophobicContact CD1-CB 3.94Å; R252-M256 VanDerWaalsContact O-CB 3.3Å; R252-M256 WeakPolarHBondContact O-CB 3.3Å; R252-M256 PolarHBondContact O-N 2.88Å; L253-M256 PolarHBondContact O-N 3.24Å
257Y94.6Very high95.4Very high31 Ų3141.2 Ų41.212%0.12222%0.223CC..THydrogen-bonded Turntrans-98.68.1-178.2-76.5-78.9000114.5R74 W75 F77 L161 L253 R255 C259R74-Y257 HydrophobicContact CB-CE1 4Å; W75-Y257 PolarHBondContact N-OH 3.1Å; W75-Y257 WeakPolarHBondContact O-CE1 3.49Å; F77-Y257 HydrophobicContact CD2-CD1 4.44Å; F77-Y257 HydrophobicContact CE1-CD1 4.12Å; F77-Y257 AromaticContact CE1-CE1 3.8Å; F77-Y257 HydrophobicContact CE1-CE1 3.8Å; F77-Y257 AromaticContact CE2-CD1 3.42Å; F77-Y257 HydrophobicContact CE2-CD1 3.42Å; F77-Y257 VanDerWaalsContact CE2-CD1 3.42Å; F77-Y257 HydrophobicContact CE2-CD2 4.28Å; F77-Y257 AromaticContact CE2-CE1 3.98Å; F77-Y257 HydrophobicContact CE2-CE1 3.98Å; F77-Y257 AromaticContact CE2-CG 3.58Å; F77-Y257 HydrophobicContact CE2-CG 3.58Å; F77-Y257 AromaticContact CZ-CD1 3.21Å; F77-Y257 HydrophobicContact CZ-CD1 3.21Å; F77-Y257 AromaticContact CZ-CD2 3.81Å; F77-Y257 HydrophobicContact CZ-CD2 3.81Å; F77-Y257 AromaticContact CZ-CE1 3.29Å; F77-Y257 HydrophobicContact CZ-CE1 3.29Å; F77-Y257 AromaticContact CZ-CE2 3.84Å; F77-Y257 HydrophobicContact CZ-CE2 3.84Å; F77-Y257 AromaticContact CZ-CG 3.48Å; F77-Y257 HydrophobicContact CZ-CG 3.48Å; F77-Y257 VanDerWaalsContact CZ-CG 3.48Å; F77-Y257 AromaticContact CZ-CZ 3.59Å; L161-Y257 HydrophobicContact CB-CE2 4.21Å; L161-Y257 HydrophobicContact CD2-CE2 3.78Å; L161-Y257 WeakPolarHBondContact CD2-OH 3.31Å; L161-Y257 PolarHBondContact O-OH 3.16Å; L253-Y257 HydrophobicContact CD1-CD2 3.73Å; L253-Y257 HydrophobicContact CD1-CE2 3.92Å; L253-Y257 PolarHBondContact O-N 3.41Å; R255-Y257 PolarHBondContact O-N 3.05Å; Y257-C259 PolarHBondContact O-N 2.91Å
258N95.2Very high95.4Very high131 Ų13140.6 Ų40.670%0.70121%0.211SC*.THydrogen-bonded Turntrans51.542-177-59.9-37.6000112.9N254 R255 T260N254-N258 CarbonylContact O-C 3.53Å; N254-N258 WeakPolarHBondContact O-CA 3.24Å; N254-N258 PolarHBondContact O-N 2.97Å; R255-N258 PolarHBondContact O-N 3.32Å; R255-N258 PolarHBondContact O-OD1 3.45Å; N258-T260 PolarHBondContact O-N 2.92Å
259C95.6Very high95.4Very high25 Ų2539.1 Ų39.117%0.16920%0.204CC..  trans-70.2116.6-179.1-62.80000110.8C107 N254 Y257C107-C259 HydrophobicContact CB-CB 3.54Å; C107-C259 WeakPolarHBondContact CB-SG 3.43Å; C107-C259 PolarHBondContact N-SG 3.42Å; C107-C259 WeakPolarHBondContact SG-CA 3.31Å; C107-C259 WeakPolarHBondContact SG-CB 3.45Å; C107-C259 CovalentContact SG-SG 2.04Å; C107-C259 PolarHBondContact SG-SG 2.97Å; N254-C259 HydrophobicContact CB-CB 3.85Å; N254-C259 PolarHBondContact O-N 2.55Å; N254-C259 WeakPolarHBondContact OD1-CB 3.41Å; N254-C259 PolarHBondContact OD1-SG 3.48Å; Y257-C259 PolarHBondContact O-N 2.91Å
260T93.1Very high95.3Very high132 Ų13240.2 Ų40.281%0.8121%0.21SC*.  trans-100.4-18.2175.456.40000113.3N258N258-T260 PolarHBondContact O-N 2.92Å
261T90.6Very high95.2Very high87 Ų8739.9 Ų39.953%0.53421%0.208SC..SBendtrans-146.2155.7-177.358.60000109.7C107C107-T261 WeakPolarHBondContact CB-O 3.19Å
262T93.9Very high95.1Very high22 Ų2239.1 Ų39.114%0.13521%0.205CC..  trans-92.6166.6170.255.20000110.7L104 S106 L265L104-T262 WeakPolarHBondContact O-CB 3.49Å; L104-T262 WeakPolarHBondContact O-CG2 3.24Å; S106-T262 WeakPolarHBondContact O-CA 3.37Å; T262-L265 VanDerWaalsContact OG1-CB 3.24Å; T262-L265 WeakPolarHBondContact OG1-CB 3.21Å
263H93.6Very high95Very high54 Ų5445.8 Ų45.825%0.2523%0.234CC..SBendtrans-83.4-42.9179.5-74.4-71000113.4R103 C107 V108 D109R103-H263 HydrophobicContact CB-CB 3.93Å; R103-H263 HydrophobicContact CG-CB 4.18Å; R103-H263 WeakPolarHBondContact O-CA 3.41Å; R103-H263 WeakPolarHBondContact O-CB 3.36Å; R103-H263 PolarHBondContact O-N 3.3Å; C107-H263 VanDerWaalsContact C-NE2 3.29Å; C107-H263 PolarHBondContact O-CD2 3.42Å; C107-H263 PolarHBondContact O-NE2 3.24Å; V108-H263 PolarHBondContact O-CD2 2.86Å; D109-H263 WeakPolarHBondContact CB-NE2 3.25Å
264T96.4Very high94.8Very high1 Ų150.3 Ų50.31%0.00627%0.272CS..SBendtrans-108.1-16-171.153.80000114.5R103 L104 L266 T427 E428 T429R103-T264 HydrophobicContact CB-CG2 3.93Å; R103-T264 PolarHBondContact O-N 3.29Å; R103-T264 PolarHBondContact O-OG1 3.09Å; L104-T264 WeakPolarHBondContact CA-OG1 3.29Å; L104-T264 PolarHBondContact N-OG1 2.8Å; T264-L266 PolarHBondContact O-N 3.14Å; T264-T427 CarbonylContact O-C 3.58Å; T264-T427 VanDerWaalsContact O-CA 3.27Å; T264-T427 WeakPolarHBondContact O-CA 3.11Å; T264-E428 HydrophobicContact CG2-CB 4.37Å; T264-E428 PolarHBondContact O-N 3.07Å; T264-T429 HydrophobicContact CG2-CG2 4.48Å
265L96.9Very high94.8Very high28 Ų2853.4 Ų53.415%0.14729%0.288CS..EExtended strand (participates in β ladder)trans-76.7118.8173-172.263.2000110.9L104 T262 D267 H268 T425 T427 V517 R518L104-L265 HydrophobicContact CD1-CB 4.32Å; T262-L265 VanDerWaalsContact OG1-CB 3.24Å; T262-L265 WeakPolarHBondContact OG1-CB 3.21Å; L265-D267 WeakPolarHBondContact CD1-O 3.31Å; L265-H268 HydrophobicContact CD1-CB 4.49Å; L265-T425 HydrophobicContact CD1-CG2 3.94Å; L265-T427 HydrophobicContact CD1-CG2 4.02Å; L265-V517 HydrophobicContact CD1-CG1 3.67Å; L265-V517 HydrophobicContact CD2-CG1 4.25Å; L265-R518 HydrophobicContact CD2-CG 3.94Å
266L96.4Very high94.8Very high25 Ų2549.8 Ų49.813%0.13128%0.276CS..EExtended strand (participates in β ladder)trans-96.9-39.8175.2-72179.3000112.6T264 R333 Y336 P337 Q342 F401 L426 E428T264-L266 PolarHBondContact O-N 3.14Å; L266-R333 PolarHBondContact O-NH2 2.9Å; L266-Y336 WeakPolarHBondContact CD2-O 3.34Å; L266-P337 HydrophobicContact CD1-CB 4.27Å; L266-Q342 HydrophobicContact CD1-CG 3.88Å; L266-F401 HydrophobicContact CD1-CE1 4.48Å; L266-L426 HydrophobicContact CB-CB 4.48Å; L266-L426 HydrophobicContact CB-CD2 3.79Å; L266-L426 HydrophobicContact CB-CG 4.07Å; L266-L426 HydrophobicContact CD1-CD2 3.87Å; L266-L426 HydrophobicContact CD1-CG 4.26Å; L266-L426 HydrophobicContact CG-CD2 4.5Å; L266-L426 PolarHBondContact N-O 2.72Å; L266-E428 HydrophobicContact CD1-CG 3.54Å; L266-E428 HydrophobicContact CD2-CG 4.05Å; L266-E428 HydrophobicContact CG-CG 3.52Å
267D96.8Very high95Very high6 Ų651.1 Ų51.13%0.03229%0.285CS..EExtended strand (participates in β ladder)trans-151.2150.5-178.7-148.94000112.9L265 R333 L335 Y403 L426L265-D267 WeakPolarHBondContact CD1-O 3.31Å; D267-R333 VanDerWaalsContact CG-NH1 3.32Å; D267-R333 IonicContact OD1-CZ 2.7Å; D267-R333 IonicContact OD1-NH1 3.63Å; D267-R333 PolarHBondContact OD1-NH1 2.8Å; D267-R333 IonicContact OD1-NH2 3.13Å; D267-R333 PolarHBondContact OD1-NH2 3.26Å; D267-R333 IonicContact OD2-CZ 3.18Å; D267-R333 IonicContact OD2-NH1 3.49Å; D267-R333 PolarHBondContact OD2-NH1 2.83Å; D267-R333 IonicContact OD2-NH2 3.98Å; D267-L335 HydrophobicContact CB-CD1 4.42Å; D267-L335 HydrophobicContact CB-CD2 3.95Å; D267-Y403 HydrophobicContact CB-CE1 4.39Å; D267-Y403 PolarHBondContact OD2-OH 3.18Å; D267-L426 HydrophobicContact CB-CB 4Å; D267-L426 PolarHBondContact N-O 3.47Å; D267-L426 PolarHBondContact O-N 3.24Å
268H96.6Very high95.2Very high42 Ų4251.2 Ų51.219%0.19430%0.296CS..EExtended strand (participates in β ladder)trans-151.5128.8174.6173.359.2000109.2L265 T270 I424 P515L265-H268 HydrophobicContact CD1-CB 4.49Å; H268-T270 WeakPolarHBondContact CE1-CG2 3.21Å; H268-T270 WeakPolarHBondContact NE2-CG2 3.21Å; H268-I424 CarbonylContact C-O 3.54Å; H268-I424 WeakPolarHBondContact CA-O 3.49Å; H268-I424 PolarHBondContact ND1-O 2.9Å; H268-P515 PolarHBondContact CE1-O 3.39Å
269C97.3Very high95.3Very high1 Ų145.4 Ų45.41%0.00726%0.264CS..EExtended strand (participates in β ladder)trans-148.7116-178.4-162.90000113.2F271 C277 I424C269-F271 VanDerWaalsContact SG-CD1 3.58Å; C269-F271 VanDerWaalsContact SG-CE1 3.6Å; C269-C277 WeakPolarHBondContact CA-SG 3.3Å; C269-C277 HydrophobicContact CB-CB 3.64Å; C269-C277 WeakPolarHBondContact CB-SG 3.38Å; C269-C277 WeakPolarHBondContact SG-CB 3.5Å; C269-C277 CovalentContact SG-SG 2.04Å; C269-C277 PolarHBondContact SG-SG 3.46Å; C269-I424 HydrophobicContact CB-CB 4.4Å; C269-I424 PolarHBondContact N-O 3.08Å; C269-I424 PolarHBondContact O-N 2.94Å
270T95.9Very high95.3Very high23 Ų2347.7 Ų47.714%0.14127%0.274CS..  trans-1055.2174.462.50000112.4H268 E272 D423 P515H268-T270 WeakPolarHBondContact CE1-CG2 3.21Å; H268-T270 WeakPolarHBondContact NE2-CG2 3.21Å; T270-E272 PolarHBondContact O-N 3.49Å; T270-E272 WeakPolarHBondContact OG1-CG 3.24Å; T270-D423 WeakPolarHBondContact CG2-OD1 3.25Å; T270-P515 HydrophobicContact CG2-CB 3.76Å
271F96Very high95.4Very high0 Ų043.7 Ų43.70%025%0.246CC..SBendtrans58.35.9-177.9-53.9-68.7000117.7C269 K273 I276 M279 H291 Y313 M315 L330 I424C269-F271 VanDerWaalsContact SG-CD1 3.58Å; C269-F271 VanDerWaalsContact SG-CE1 3.6Å; F271-K273 PolarHBondContact O-N 3.41Å; F271-I276 HydrophobicContact CD1-CB 4.13Å; F271-I276 HydrophobicContact CD1-CG2 4.19Å; F271-M279 HydrophobicContact CE1-SD 3.7Å; F271-M279 HydrophobicContact CZ-SD 3.97Å; F271-H291 PolarHBondContact O-NE2 2.91Å; F271-Y313 VanDerWaalsContact O-CB 3.29Å; F271-Y313 WeakPolarHBondContact O-CB 3.39Å; F271-M315 HydrophobicContact CD1-CG 3.58Å; F271-M315 HydrophobicContact CD1-SD 3.98Å; F271-M315 HydrophobicContact CD2-CG 4.03Å; F271-M315 HydrophobicContact CE1-CG 3.31Å; F271-M315 HydrophobicContact CE1-SD 4.1Å; F271-M315 HydrophobicContact CE2-CB 4.4Å; F271-M315 HydrophobicContact CE2-CG 3.77Å; F271-M315 HydrophobicContact CG-CG 3.91Å; F271-M315 HydrophobicContact CG-SD 4.5Å; F271-M315 HydrophobicContact CZ-CB 4.28Å; F271-M315 HydrophobicContact CZ-CG 3.38Å; F271-L330 HydrophobicContact CE1-CD2 4.39Å; F271-L330 HydrophobicContact CZ-CD2 4.24Å; F271-I424 HydrophobicContact CE1-CD1 4.4Å; F271-I424 HydrophobicContact CE2-CD1 3.73Å; F271-I424 HydrophobicContact CE2-CG1 4.36Å; F271-I424 HydrophobicContact CZ-CD1 3.35Å; F271-I424 HydrophobicContact CZ-CG1 4.42Å
272E94.3Very high95.3Very high62 Ų6240 Ų4029%0.2923%0.226SC..  trans-61.3-12.6179.4-65-52.5117.300115.3T270 T303 G312 Y313T270-E272 PolarHBondContact O-N 3.49Å; T270-E272 WeakPolarHBondContact OG1-CG 3.24Å; E272-T303 HydrophobicContact CG-CG2 4.3Å; E272-G312 WeakPolarHBondContact OE1-CA 3.2Å; E272-G312 WeakPolarHBondContact OE2-CA 3.41Å; E272-Y313 PolarHBondContact OE1-N 2.89Å
273K93.1Very high95Very high151 Ų15145.4 Ų45.466%0.65726%0.259SS*.SBendtrans-115.1140.4179.1-64.3-178-177.3174.80110.7F271 N275 I276F271-K273 PolarHBondContact O-N 3.41Å; K273-N275 VanDerWaalsContact CB-OD1 3.26Å; K273-N275 WeakPolarHBondContact CB-OD1 3.48Å; K273-N275 PolarHBondContact O-N 3.32Å; K273-I276 PolarHBondContact O-N 3.17Å
274A92.5Very high94.8Very high95 Ų9549 Ų4979%0.78528%0.284SS*.THydrogen-bonded Turntrans-59-19.7-179.600000115I276A274-I276 PolarHBondContact O-N 3.46Å
275N94.9Very high94.5Very high102 Ų10250.5 Ų50.555%0.54529%0.293SS..THydrogen-bonded Turntrans-79.4-0.8174.474.1-32.2000113.2K273 C277 G278K273-N275 VanDerWaalsContact CB-OD1 3.26Å; K273-N275 WeakPolarHBondContact CB-OD1 3.48Å; K273-N275 PolarHBondContact O-N 3.32Å; N275-C277 PolarHBondContact O-N 2.8Å; N275-G278 PolarHBondContact O-N 3.18Å
276I95.9Very high94.4Very high25 Ų2554.5 Ų54.513%0.12831%0.314CS..G310 helixtrans44.342.1178.559.5169.6000112.5F271 K273 A274 G278 M279 H291 M315F271-I276 HydrophobicContact CD1-CB 4.13Å; F271-I276 HydrophobicContact CD1-CG2 4.19Å; K273-I276 PolarHBondContact O-N 3.17Å; A274-I276 PolarHBondContact O-N 3.46Å; I276-G278 PolarHBondContact O-N 3.04Å; I276-M279 HydrophobicContact CD1-CB 4.15Å; I276-M279 WeakPolarHBondContact CD1-O 3.25Å; I276-M279 HydrophobicContact CG1-CB 4.28Å; I276-M279 WeakPolarHBondContact O-CB 3.49Å; I276-M279 VanDerWaalsContact O-CG 3.27Å; I276-M279 WeakPolarHBondContact O-CG 3.34Å; I276-M279 PolarHBondContact O-N 3.31Å; I276-H291 HydrophobicContact CG2-CB 4.41Å; I276-M315 HydrophobicContact CG2-SD 4.24Å
277C96.5Very high94.3Very high31 Ų3155.3 Ų55.321%0.20932%0.32CS..G310 helixtrans59.517.7179.8-38.40000114.8C269 N275 R333C269-C277 WeakPolarHBondContact CA-SG 3.3Å; C269-C277 HydrophobicContact CB-CB 3.64Å; C269-C277 WeakPolarHBondContact CB-SG 3.38Å; C269-C277 WeakPolarHBondContact SG-CB 3.5Å; C269-C277 CovalentContact SG-SG 2.04Å; C269-C277 PolarHBondContact SG-SG 3.46Å; N275-C277 PolarHBondContact O-N 2.8Å; C277-R333 PolarHBondContact O-NH1 2.73Å
278G97.1Very high94.2Very high33 Ų3359.1 Ų59.134%0.3434%0.341SS..G310 helixtrans79.215.3-174.800000114.1N275 I276N275-G278 PolarHBondContact O-N 3.18Å; I276-G278 PolarHBondContact O-N 3.04Å
279M97.8Very high94.2Very high9 Ų957.5 Ų57.54%0.04433%0.333CS..  trans-66.1153.2169.5-60.2-167.784.800110.6F271 I276 L330 E331 Y403 F405 I424F271-M279 HydrophobicContact CE1-SD 3.7Å; F271-M279 HydrophobicContact CZ-SD 3.97Å; I276-M279 HydrophobicContact CD1-CB 4.15Å; I276-M279 WeakPolarHBondContact CD1-O 3.25Å; I276-M279 HydrophobicContact CG1-CB 4.28Å; I276-M279 WeakPolarHBondContact O-CB 3.49Å; I276-M279 VanDerWaalsContact O-CG 3.27Å; I276-M279 WeakPolarHBondContact O-CG 3.34Å; I276-M279 PolarHBondContact O-N 3.31Å; M279-L330 HydrophobicContact CB-CD1 3.98Å; M279-L330 HydrophobicContact CB-CG 4.49Å; M279-L330 HydrophobicContact CE-CD2 4.06Å; M279-L330 HydrophobicContact CE-CG 3.85Å; M279-L330 HydrophobicContact SD-CD2 4.15Å; M279-L330 HydrophobicContact SD-CG 4.3Å; M279-E331 CarbonylContact C-O 3.51Å; M279-E331 WeakPolarHBondContact CA-O 3.32Å; M279-E331 WeakPolarHBondContact CB-O 3.46Å; M279-Y403 HydrophobicContact CE-CE2 3.78Å; M279-F405 HydrophobicContact CE-CD2 4.29Å; M279-F405 HydrophobicContact CE-CE2 4.32Å; M279-I424 HydrophobicContact CE-CD1 4.36Å; M279-I424 HydrophobicContact SD-CD1 4.08Å
280I96.8Very high94.1Very high73 Ų7360.9 Ų60.937%0.37435%0.354SS..EExtended strand (participates in β ladder)trans-128.3148.5-17863.4171.3000110.4E331I280-E331 HydrophobicContact CD1-CB 4.49Å; I280-E331 HydrophobicContact CG1-CB 3.81Å; I280-E331 HydrophobicContact CG1-CG 4.32Å; I280-E331 PolarHBondContact N-O 3.03Å; I280-E331 PolarHBondContact O-N 3.32Å
281Q94.2Very high94Very high47 Ų4762.7 Ų62.722%0.2236%0.36CS..EExtended strand (participates in β ladder)trans-81.7160.1170.5-59.1-75-21.400110.4W289 L329Q281-W289 PolarHBondContact NE2-O 3.46Å; Q281-L329 CarbonylContact C-O 3.44Å; Q281-L329 VanDerWaalsContact CA-O 3.3Å; Q281-L329 WeakPolarHBondContact CA-O 3.34Å; Q281-L329 PolarHBondContact OE1-O 2.88Å
282G88.8Confident93.8Very high10 Ų1064.5 Ų64.510%0.10337%0.368CS..  trans-60.8162.1162.400000111.5D285 L329G282-D285 WeakPolarHBondContact CA-OD1 3.41Å; G282-L329 PolarHBondContact N-O 3.03Å
283T87.7Confident93.5Very high136 Ų13664.2 Ų64.283%0.83437%0.369SS*.SBendtrans-122.10.8175.164.20000112.7D285T283-D285 PolarHBondContact N-OD1 2.73Å
284T88.1Confident93.2Very high128 Ų12857.3 Ų57.379%0.78534%0.34SS*.SBendtrans-134.62.2-171.660.20000112.4
285D91.3Very high92.5Very high33 Ų3355.4 Ų55.418%0.17632%0.324CS..SBendtrans-82.1168.4173.248.3-31.8000111G282 T283 A328 L329G282-D285 WeakPolarHBondContact CA-OD1 3.41Å; T283-D285 PolarHBondContact N-OD1 2.73Å; D285-A328 WeakPolarHBondContact OD2-CA 2.97Å; D285-L329 HydrophobicContact CB-CD1 4.38Å; D285-L329 HydrophobicContact CB-CG 4.19Å; D285-L329 WeakPolarHBondContact OD2-CB 3.34Å; D285-L329 PolarHBondContact OD2-N 3.08Å
286D94.3Very high91.4Very high112 Ų11255.6 Ų55.660%0.59932%0.322SS*.SBendtrans-83.2-26.2-167.9-51.3-64.4000112.4E326 A327D286-E326 HydrophobicContact CB-CB 3.9Å; D286-E326 HydrophobicContact CB-CG 3.82Å; D286-E326 WeakPolarHBondContact OD2-CA 3.28Å; D286-A327 PolarHBondContact N-O 3.49Å; D286-A327 VanDerWaalsContact N-O 3.15Å; D286-A327 PolarHBondContact OD2-N 3.04Å; D286-A327 VanDerWaalsContact OD2-N 3.14Å
287T94.1Very high89.9Confident42 Ų4259.6 Ų59.626%0.25836%0.359SS..SBendtrans-155.4170.4-178.3-1720000110.6L317 E326 A327 A328T287-L317 HydrophobicContact CG2-CD1 3.89Å; T287-E326 HydrophobicContact CG2-CB 4.42Å; T287-A327 PolarHBondContact N-O 3.39Å; T287-A328 HydrophobicContact CG2-CB 4.13Å; T287-A328 WeakPolarHBondContact O-CA 3.32Å; T287-A328 WeakPolarHBondContact O-CB 3.42Å
288D94.7Very high88.4Confident87 Ų8760.8 Ų60.847%0.46538%0.376SS..  trans-118153.1-171.8-70.1-48.8000112.2
289W96.4Very high87.4Confident7 Ų761.3 Ų61.33%0.02737%0.37CS..  trans-73.3140.1163.6-66.280.4000110.3Q281 M315 L317 A328 L330 L358 F405 I419 L421Q281-W289 PolarHBondContact NE2-O 3.46Å; W289-M315 HydrophobicContact CB-CE 3.52Å; W289-M315 HydrophobicContact CE3-CB 3.97Å; W289-L317 HydrophobicContact CD2-CB 4.06Å; W289-L317 HydrophobicContact CE3-CB 3.89Å; W289-L317 HydrophobicContact CH2-CB 4.25Å; W289-L317 HydrophobicContact CZ2-CB 4.42Å; W289-L317 HydrophobicContact CZ3-CB 3.99Å; W289-A328 HydrophobicContact CG-CB 4.31Å; W289-A328 PolarHBondContact NE1-O 3.09Å; W289-A328 VanDerWaalsContact NE1-O 3.09Å; W289-L330 HydrophobicContact CD2-CB 4.5Å; W289-L330 HydrophobicContact CG-CB 4.05Å; W289-L358 HydrophobicContact CH2-CD1 4.14Å; W289-L358 HydrophobicContact CZ2-CD1 4.1Å; W289-F405 HydrophobicContact CZ2-CB 4.38Å; W289-I419 HydrophobicContact CH2-CB 4.11Å; W289-I419 HydrophobicContact CH2-CG2 3.75Å; W289-I419 HydrophobicContact CZ3-CB 4.45Å; W289-I419 HydrophobicContact CZ3-CG2 4.34Å; W289-I419 WeakPolarHBondContact CZ3-O 3.33Å; W289-L421 HydrophobicContact CE3-CD1 4.25Å; W289-L421 HydrophobicContact CH2-CD1 3.37Å; W289-L421 HydrophobicContact CH2-CG 3.67Å; W289-L421 HydrophobicContact CZ2-CD1 3.78Å; W289-L421 HydrophobicContact CZ3-CB 4.4Å; W289-L421 HydrophobicContact CZ3-CD1 3.64Å; W289-L421 HydrophobicContact CZ3-CG 3.74Å
290V95.1Very high86.8Confident73 Ų7362.8 Ų62.844%0.44238%0.379SS..EExtended strand (participates in β ladder)trans-103.9129.7179.2-176.60000109.5Q292 M315 Q316V290-Q292 PolarHBondContact O-N 3.42Å; V290-M315 WeakPolarHBondContact O-CA 3.11Å; V290-Q316 PolarHBondContact N-O 3.18Å; V290-Q316 PolarHBondContact O-N 3.38Å
291H95.2Very high86.4Confident61 Ų6159.3 Ų59.328%0.28236%0.361SS..EExtended strand (participates in β ladder)trans-77.8104168.5-179.5-139.8000108.1F271 I276 Y313 M315F271-H291 PolarHBondContact O-NE2 2.91Å; I276-H291 HydrophobicContact CG2-CB 4.41Å; H291-Y313 AromaticContact CE1-CD1 3.52Å; H291-Y313 AromaticContact CE1-CG 3.92Å; H291-Y313 VanDerWaalsContact NE2-CB 3.28Å; H291-Y313 WeakPolarHBondContact NE2-CB 3.05Å; H291-Y313 AromaticContact NE2-CD1 3.36Å; H291-Y313 WeakPolarHBondContact NE2-CD1 3.39Å; H291-Y313 AromaticContact NE2-CG 3.47Å; H291-M315 HydrophobicContact CB-CE 4.4Å; H291-M315 HydrophobicContact CB-SD 3.82Å
292Q91.6Very high86.3Confident37 Ų3757.1 Ų57.117%0.17335%0.351CS..EExtended strand (participates in β ladder)trans-110.9142.2-169.4-175.357.148.600110V290 Y313 F314 Q316V290-Q292 PolarHBondContact O-N 3.42Å; Q292-Y313 WeakPolarHBondContact O-CA 3.35Å; Q292-F314 HydrophobicContact CB-CD2 4.36Å; Q292-F314 HydrophobicContact CB-CE1 4.46Å; Q292-F314 HydrophobicContact CB-CE2 3.81Å; Q292-F314 HydrophobicContact CB-CZ 3.88Å; Q292-F314 HydrophobicContact CG-CE1 4.36Å; Q292-F314 HydrophobicContact CG-CE2 4Å; Q292-F314 HydrophobicContact CG-CZ 3.65Å; Q292-F314 PolarHBondContact N-O 3.44Å; Q292-F314 PolarHBondContact O-N 3.45Å; Q292-F314 VanDerWaalsContact O-N 3.07Å; Q292-Q316 HydrophobicContact CB-CB 4.34Å
293D88.4Confident86.3Confident56 Ų5657.4 Ų57.430%0.29935%0.351SS..EExtended strand (participates in β ladder)trans-87157172.162.229000111.8A295 Y313D293-A295 PolarHBondContact O-N 3.33Å; D293-A295 WeakPolarHBondContact OD1-CB 3.21Å; D293-A295 PolarHBondContact OD1-N 3.27Å; D293-Y313 HydrophobicContact CB-CD1 4.08Å; D293-Y313 HydrophobicContact CB-CE1 3.74Å
294S86.4Confident86.3Confident6 Ų653.7 Ų53.74%0.04233%0.325CS..THydrogen-bonded Turntrans-77.630.8175-59.60000113.8D301 A311 G312S294-D301 VanDerWaalsContact OG-CB 3.3Å; S294-D301 WeakPolarHBondContact OG-CB 3.47Å; S294-D301 VanDerWaalsContact OG-CG 3.23Å; S294-D301 PolarHBondContact OG-N 3.03Å; S294-D301 PolarHBondContact OG-OD1 2.79Å; S294-A311 WeakPolarHBondContact CB-O 3.48Å; S294-G312 PolarHBondContact N-O 2.78Å; S294-G312 VanDerWaalsContact N-O 3.1Å; S294-G312 PolarHBondContact OG-O 3.07Å
295A76.4Confident86Confident55 Ų5549.2 Ų49.246%0.45530%0.296SS..THydrogen-bonded Turntrans-76.9-23.6-179.200000113.1D293D293-A295 PolarHBondContact O-N 3.33Å; D293-A295 WeakPolarHBondContact OD1-CB 3.21Å; D293-A295 PolarHBondContact OD1-N 3.27Å
296Q72.6Confident84.9Confident107 Ų10748.7 Ų48.750%0.530%0.299SS..SBendtrans-89.6135-177-60.4-168.235.100111.9G298 E299Q296-G298 PolarHBondContact O-N 2.96Å; Q296-E299 HydrophobicContact CB-CB 4.28Å; Q296-E299 PolarHBondContact O-N 3.39Å
297A64.3Low83.9Confident109 Ų10951 Ų5190%0.90131%0.306SS*.THydrogen-bonded Turntrans-65.5122.5179.300000111.1
298G66.1Low83Confident56 Ų5652.5 Ų52.558%0.57732%0.317SS*.THydrogen-bonded Turntrans94.3-11.5-17900000114.9Q296 K349Q296-G298 PolarHBondContact O-N 2.96Å; G298-K349 PolarHBondContact O-NZ 3.38Å
299E75.4Confident81.8Confident44 Ų4454.7 Ų54.721%0.20633%0.334CS..  trans-113.271.3175.2-60.4-171.2173.200109Q296 F314 Q316 Y420Q296-E299 HydrophobicContact CB-CB 4.28Å; Q296-E299 PolarHBondContact O-N 3.39Å; E299-F314 HydrophobicContact CB-CZ 4.13Å; E299-F314 WeakPolarHBondContact O-CE1 3.34Å; E299-Q316 PolarHBondContact OE1-NE2 2.9Å; E299-Q316 PolarHBondContact OE2-NE2 3.27Å; E299-Y420 HydrophobicContact CG-CE1 4.4Å
300V84.3Confident80.6Confident40 Ų4056 Ų5624%0.24235%0.35CS..  trans-103.4137.9179.1-610000110.3W388V300-W388 WeakPolarHBondContact O-CZ2 3.38Å; V300-W388 PolarHBondContact O-NE1 2.88Å
301D88.9Confident79.9Confident0 Ų054.2 Ų54.20%034%0.343CS..  trans-52.6156.3166.569.6-52.3000111.6S294 T303 L304 L305 G306 G312 F314S294-D301 VanDerWaalsContact OG-CB 3.3Å; S294-D301 WeakPolarHBondContact OG-CB 3.47Å; S294-D301 VanDerWaalsContact OG-CG 3.23Å; S294-D301 PolarHBondContact OG-N 3.03Å; S294-D301 PolarHBondContact OG-OD1 2.79Å; D301-T303 VanDerWaalsContact OD2-CB 3.27Å; D301-T303 WeakPolarHBondContact OD2-CB 3.31Å; D301-T303 PolarHBondContact OD2-N 2.83Å; D301-L304 WeakPolarHBondContact OD2-CB 3.48Å; D301-L304 PolarHBondContact OD2-N 2.81Å; D301-L305 VanDerWaalsContact O-CA 3.25Å; D301-L305 WeakPolarHBondContact O-CA 3.41Å; D301-L305 PolarHBondContact O-N 3.41Å; D301-G306 PolarHBondContact OD1-N 2.72Å; D301-G312 WeakPolarHBondContact OD2-CA 3.25Å; D301-F314 HydrophobicContact CB-CB 4.43Å; D301-F314 HydrophobicContact CB-CD1 3.8Å
302H92.9Very high79.7Confident1 Ų151.3 Ų51.31%0.00533%0.33CS..THydrogen-bonded Turntrans-79.7-33.7172.1-174.3-98.6000110.8L304 F347 W388 D422 D423 K583H302-L304 PolarHBondContact O-N 2.86Å; H302-F347 HydrophobicContact CB-CB 4.27Å; H302-F347 AromaticContact CD2-CD1 3.7Å; H302-F347 AromaticContact CE1-CD1 3.45Å; H302-F347 VanDerWaalsContact CE1-CD1 3.45Å; H302-F347 WeakPolarHBondContact CE1-CD1 3.49Å; H302-F347 AromaticContact CE1-CD2 3.7Å; H302-F347 AromaticContact CE1-CE1 3.3Å; H302-F347 WeakPolarHBondContact CE1-CE1 3.37Å; H302-F347 AromaticContact CE1-CE2 3.55Å; H302-F347 AromaticContact CE1-CG 3.63Å; H302-F347 AromaticContact CE1-CZ 3.34Å; H302-F347 WeakPolarHBondContact CE1-CZ 3.25Å; H302-F347 AromaticContact CG-CD1 3.96Å; H302-F347 AromaticContact CG-CG 3.86Å; H302-F347 AromaticContact ND1-CD1 3.82Å; H302-F347 AromaticContact ND1-CD2 3.66Å; H302-F347 AromaticContact ND1-CE2 3.94Å; H302-F347 AromaticContact ND1-CG 3.58Å; H302-F347 AromaticContact NE2-CD1 3.38Å; H302-F347 WeakPolarHBondContact NE2-CD1 3.33Å; H302-F347 AromaticContact NE2-CE1 3.29Å; H302-F347 VanDerWaalsContact NE2-CE1 3.29Å; H302-F347 WeakPolarHBondContact NE2-CE1 3.25Å; H302-F347 AromaticContact NE2-CG 3.97Å; H302-F347 AromaticContact NE2-CZ 3.82Å; H302-W388 HydrophobicContact CB-CD2 3.94Å; H302-W388 HydrophobicContact CB-CE3 4.19Å; H302-W388 HydrophobicContact CB-CG 4.4Å; H302-W388 HydrophobicContact CB-CH2 4.38Å; H302-W388 HydrophobicContact CB-CZ2 4.15Å; H302-W388 HydrophobicContact CB-CZ3 4.39Å; H302-W388 AromaticContact CD2-CG 3.86Å; H302-D422 WeakPolarHBondContact CA-OD2 3.36Å; H302-D422 HydrophobicContact CB-CB 3.97Å; H302-D422 PolarHBondContact N-OD2 3.22Å; H302-D423 IonicContact CE1-OD2 2.83Å; H302-D423 IonicContact CG-OD2 3.75Å; H302-D423 IonicContact ND1-OD2 3.46Å; H302-D423 PolarHBondContact ND1-OD2 2.96Å; H302-K583 WeakPolarHBondContact O-CE 3.48Å; H302-K583 PolarHBondContact O-NZ 3.13Å
303T88.8Confident79.8Confident15 Ų1553.1 Ų53.19%0.09234%0.335CS..THydrogen-bonded Turntrans-50.9-56.6-175.6-58.80000112.4E272 D301 D422 D423 P515 K583E272-T303 HydrophobicContact CG-CG2 4.3Å; D301-T303 VanDerWaalsContact OD2-CB 3.27Å; D301-T303 WeakPolarHBondContact OD2-CB 3.31Å; D301-T303 PolarHBondContact OD2-N 2.83Å; T303-D422 PolarHBondContact N-OD2 2.96Å; T303-D422 PolarHBondContact OG1-OD1 2.97Å; T303-D422 PolarHBondContact OG1-OD2 2.93Å; T303-D422 VanDerWaalsContact OG1-OD2 3.13Å; T303-D423 PolarHBondContact OG1-OD1 3.18Å; T303-P515 HydrophobicContact CG2-CB 4.02Å; T303-P515 HydrophobicContact CG2-CG 3.62Å; T303-K583 VanDerWaalsContact O-CE 3.32Å; T303-K583 WeakPolarHBondContact O-CE 3.33Å; T303-K583 PolarHBondContact O-NZ 3.09Å
304L87.4Confident80.1Confident58 Ų5850.4 Ų50.430%0.30432%0.321SS..THydrogen-bonded Turntrans-111.3-8.6-175.9-57.5-178.4000113.7D301 H302 G306 Q307 A311D301-L304 WeakPolarHBondContact OD2-CB 3.48Å; D301-L304 PolarHBondContact OD2-N 2.81Å; H302-L304 PolarHBondContact O-N 2.86Å; L304-G306 PolarHBondContact O-N 2.91Å; L304-G306 VanDerWaalsContact O-N 3.13Å; L304-Q307 VanDerWaalsContact O-CB 3.27Å; L304-Q307 WeakPolarHBondContact O-CB 3.4Å; L304-Q307 WeakPolarHBondContact O-CG 3.46Å; L304-Q307 PolarHBondContact O-N 3.12Å; L304-A311 HydrophobicContact CD1-CB 4.05Å
305L82.2Confident80.6Confident34 Ų3450.2 Ų50.218%0.17832%0.319CS..THydrogen-bonded Turntrans5232.6-177.5-63.4175.2000113.8D301 Q307 K583 N584D301-L305 VanDerWaalsContact O-CA 3.25Å; D301-L305 WeakPolarHBondContact O-CA 3.41Å; D301-L305 PolarHBondContact O-N 3.41Å; L305-Q307 PolarHBondContact O-N 3.33Å; L305-Q307 VanDerWaalsContact O-N 3.14Å; L305-K583 HydrophobicContact CD1-CG 3.5Å; L305-K583 VanDerWaalsContact CD1-CG 3.5Å; L305-K583 HydrophobicContact CG-CG 4.25Å; L305-N584 HydrophobicContact CD1-CB 3.9Å; L305-N584 HydrophobicContact CD2-CB 4.02Å
306G66.3Low81.5Confident22 Ų2248.5 Ų48.523%0.22730%0.302CS..THydrogen-bonded Turntrans62.218.6-177.300000114.7D301 L304 C308D301-G306 PolarHBondContact OD1-N 2.72Å; L304-G306 PolarHBondContact O-N 2.91Å; L304-G306 VanDerWaalsContact O-N 3.13Å; G306-C308 PolarHBondContact O-N 2.48Å; G306-C308 VanDerWaalsContact O-N 3.13Å
307Q73.4Confident82.6Confident162 Ų16243.5 Ų43.576%0.75728%0.278SS*.SBendtrans-55-28.2172.3-74.317711.600111.9L304 L305L304-Q307 VanDerWaalsContact O-CB 3.27Å; L304-Q307 WeakPolarHBondContact O-CB 3.4Å; L304-Q307 WeakPolarHBondContact O-CG 3.46Å; L304-Q307 PolarHBondContact O-N 3.12Å; L305-Q307 PolarHBondContact O-N 3.33Å; L305-Q307 VanDerWaalsContact O-N 3.14Å
308C75.1Confident84.1Confident72 Ų7240.6 Ų40.649%0.48625%0.251SS..SBendtrans-120.2108.9175.1-71.30000109.2G306 G310 A311G306-C308 PolarHBondContact O-N 2.48Å; G306-C308 VanDerWaalsContact O-N 3.13Å; C308-G310 PolarHBondContact O-N 3.27Å; C308-A311 HydrophobicContact CB-CB 3.63Å; C308-A311 PolarHBondContact O-N 3.16Å
309T70.4Confident85.4Confident133 Ų13337.9 Ų37.982%0.81622%0.224SC*.THydrogen-bonded Turntrans-57.3125.3-178.9-50.10000111.6A311T309-A311 PolarHBondContact O-N 3.24Å
310G70.8Confident86.3Confident36 Ų3638.4 Ų38.437%0.37123%0.232SC..THydrogen-bonded Turntrans71.611.7-178.600000114.6C308C308-G310 PolarHBondContact O-N 3.27Å
311A80.6Confident86.6Confident35 Ų3539.9 Ų39.929%0.28924%0.244SC..  trans-111.5151.8163.500000108.6S294 L304 C308 T309S294-A311 WeakPolarHBondContact CB-O 3.48Å; L304-A311 HydrophobicContact CD1-CB 4.05Å; C308-A311 HydrophobicContact CB-CB 3.63Å; C308-A311 PolarHBondContact O-N 3.16Å; T309-A311 PolarHBondContact O-N 3.24Å
312G90.4Very high86.7Confident0 Ų042 Ų420%027%0.266CS..  trans95.1137.6-171.600000111.4E272 S294 D301E272-G312 WeakPolarHBondContact OE1-CA 3.2Å; E272-G312 WeakPolarHBondContact OE2-CA 3.41Å; S294-G312 PolarHBondContact N-O 2.78Å; S294-G312 VanDerWaalsContact N-O 3.1Å; S294-G312 PolarHBondContact OG-O 3.07Å; D301-G312 WeakPolarHBondContact OD2-CA 3.25Å
313Y93.7Very high86.8Confident74 Ų7445.3 Ų45.329%0.2929%0.289SS..EExtended strand (participates in β ladder)trans-138.8150.6-178.1-69.3-89.8000111.5F271 E272 H291 Q292 D293F271-Y313 VanDerWaalsContact O-CB 3.29Å; F271-Y313 WeakPolarHBondContact O-CB 3.39Å; E272-Y313 PolarHBondContact OE1-N 2.89Å; H291-Y313 AromaticContact CE1-CD1 3.52Å; H291-Y313 AromaticContact CE1-CG 3.92Å; H291-Y313 VanDerWaalsContact NE2-CB 3.28Å; H291-Y313 WeakPolarHBondContact NE2-CB 3.05Å; H291-Y313 AromaticContact NE2-CD1 3.36Å; H291-Y313 WeakPolarHBondContact NE2-CD1 3.39Å; H291-Y313 AromaticContact NE2-CG 3.47Å; Q292-Y313 WeakPolarHBondContact O-CA 3.35Å; D293-Y313 HydrophobicContact CB-CD1 4.08Å; D293-Y313 HydrophobicContact CB-CE1 3.74Å
314F95.1Very high87.1Confident0 Ų047.3 Ų47.30%031%0.307CS..EExtended strand (participates in β ladder)trans-147.5171.3176.256.5-86.4000110.2Q292 E299 D301 Q316 Y420 D422Q292-F314 HydrophobicContact CB-CD2 4.36Å; Q292-F314 HydrophobicContact CB-CE1 4.46Å; Q292-F314 HydrophobicContact CB-CE2 3.81Å; Q292-F314 HydrophobicContact CB-CZ 3.88Å; Q292-F314 HydrophobicContact CG-CE1 4.36Å; Q292-F314 HydrophobicContact CG-CE2 4Å; Q292-F314 HydrophobicContact CG-CZ 3.65Å; Q292-F314 PolarHBondContact N-O 3.44Å; Q292-F314 PolarHBondContact O-N 3.45Å; Q292-F314 VanDerWaalsContact O-N 3.07Å; E299-F314 HydrophobicContact CB-CZ 4.13Å; E299-F314 WeakPolarHBondContact O-CE1 3.34Å; D301-F314 HydrophobicContact CB-CB 4.43Å; D301-F314 HydrophobicContact CB-CD1 3.8Å; F314-Q316 HydrophobicContact CD2-CB 4.14Å; F314-Q316 HydrophobicContact CE2-CB 3.82Å; F314-Q316 HydrophobicContact CE2-CG 4.23Å; F314-Y420 AromaticContact CD2-CD1 3.68Å; F314-Y420 HydrophobicContact CD2-CD1 3.68Å; F314-Y420 HydrophobicContact CD2-CE1 4.45Å; F314-Y420 AromaticContact CE2-CD1 3.34Å; F314-Y420 HydrophobicContact CE2-CD1 3.34Å; F314-Y420 AromaticContact CE2-CE1 3.67Å; F314-Y420 HydrophobicContact CE2-CE1 3.67Å; F314-Y420 HydrophobicContact CZ-CD1 4.2Å; F314-Y420 HydrophobicContact CZ-CE1 4.28Å; F314-D422 HydrophobicContact CB-CB 4.24Å
315M97.2Very high87.4Confident1 Ų149.6 Ų49.61%0.00532%0.316CS..EExtended strand (participates in β ladder)trans-100.3128.1171.3-62.2-61.3-55.300110F271 I276 W289 V290 H291 L330 Y420 L421F271-M315 HydrophobicContact CD1-CG 3.58Å; F271-M315 HydrophobicContact CD1-SD 3.98Å; F271-M315 HydrophobicContact CD2-CG 4.03Å; F271-M315 HydrophobicContact CE1-CG 3.31Å; F271-M315 HydrophobicContact CE1-SD 4.1Å; F271-M315 HydrophobicContact CE2-CB 4.4Å; F271-M315 HydrophobicContact CE2-CG 3.77Å; F271-M315 HydrophobicContact CG-CG 3.91Å; F271-M315 HydrophobicContact CG-SD 4.5Å; F271-M315 HydrophobicContact CZ-CB 4.28Å; F271-M315 HydrophobicContact CZ-CG 3.38Å; I276-M315 HydrophobicContact CG2-SD 4.24Å; W289-M315 HydrophobicContact CB-CE 3.52Å; W289-M315 HydrophobicContact CE3-CB 3.97Å; V290-M315 WeakPolarHBondContact O-CA 3.11Å; H291-M315 HydrophobicContact CB-CE 4.4Å; H291-M315 HydrophobicContact CB-SD 3.82Å; M315-L330 HydrophobicContact CB-CD2 4.12Å; M315-L330 HydrophobicContact CE-CD1 4.23Å; M315-L330 HydrophobicContact CE-CD2 4.33Å; M315-L330 HydrophobicContact CG-CD2 3.77Å; M315-Y420 CarbonylContact O-C 3.55Å; M315-Y420 WeakPolarHBondContact O-CA 3.31Å; M315-L421 HydrophobicContact CB-CB 4.36Å; M315-L421 PolarHBondContact N-O 2.74Å; M315-L421 PolarHBondContact O-N 3.3Å
316Q95.7Very high88.1Confident20 Ų2049.9 Ų49.99%0.09332%0.317CS..EExtended strand (participates in β ladder)trans-121.4134.6-178.5-166.4-173.524.800111.2V290 Q292 E299 F314 I419 Y420V290-Q316 PolarHBondContact N-O 3.18Å; V290-Q316 PolarHBondContact O-N 3.38Å; Q292-Q316 HydrophobicContact CB-CB 4.34Å; E299-Q316 PolarHBondContact OE1-NE2 2.9Å; E299-Q316 PolarHBondContact OE2-NE2 3.27Å; F314-Q316 HydrophobicContact CD2-CB 4.14Å; F314-Q316 HydrophobicContact CE2-CB 3.82Å; F314-Q316 HydrophobicContact CE2-CG 4.23Å; Q316-I419 CarbonylContact C-O 3.56Å; Q316-I419 WeakPolarHBondContact CA-O 2.97Å; Q316-Y420 HydrophobicContact CB-CD1 4.45Å; Q316-Y420 HydrophobicContact CG-CD1 3.95Å; Q316-Y420 HydrophobicContact CG-CE1 3.63Å; Q316-Y420 VanDerWaalsContact NE2-CE1 3.3Å; Q316-Y420 PolarHBondContact NE2-OH 2.81Å
317L95.9Very high89.6Confident1 Ų149.4 Ų49.41%0.00531%0.311CS..EExtended strand (participates in β ladder)trans-110.4111.9162.2173.862.7000108.4T287 W289 T319 A328 G418 I419T287-L317 HydrophobicContact CG2-CD1 3.89Å; W289-L317 HydrophobicContact CD2-CB 4.06Å; W289-L317 HydrophobicContact CE3-CB 3.89Å; W289-L317 HydrophobicContact CH2-CB 4.25Å; W289-L317 HydrophobicContact CZ2-CB 4.42Å; W289-L317 HydrophobicContact CZ3-CB 3.99Å; L317-T319 HydrophobicContact CG-CG2 4.39Å; L317-T319 PolarHBondContact O-N 3.32Å; L317-A328 HydrophobicContact CD1-CB 3.69Å; L317-A328 HydrophobicContact CD2-CB 4.06Å; L317-A328 HydrophobicContact CG-CB 4.42Å; L317-G418 CarbonylContact O-C 3.46Å; L317-G418 WeakPolarHBondContact O-CA 3.3Å; L317-I419 HydrophobicContact CB-CB 4.39Å; L317-I419 HydrophobicContact CD2-CD1 4.33Å; L317-I419 PolarHBondContact N-O 3.13Å; L317-I419 PolarHBondContact O-N 2.95Å
318S95Very high90.7Very high48 Ų4841.7 Ų41.734%0.33628%0.275SS..EExtended strand (participates in β ladder)trans-69.1127.5172.4176.90000110.4S320 K409S318-S320 PolarHBondContact OG-OG 2.75Å; S318-K409 VanDerWaalsContact O-CE 3.3Å; S318-K409 WeakPolarHBondContact O-CE 3.26Å
319T94.8Very high91.8Very high0 Ų039.8 Ų39.80%026%0.26CS..  trans-111.10.1177.466.70000112.9L317 S321 D356 K409 P412 S415 G417 I419L317-T319 HydrophobicContact CG-CG2 4.39Å; L317-T319 PolarHBondContact O-N 3.32Å; T319-S321 VanDerWaalsContact C-N 3.27Å; T319-S321 PolarHBondContact O-N 2.99Å; T319-D356 VanDerWaalsContact CB-OD2 3.26Å; T319-D356 WeakPolarHBondContact CB-OD2 3.48Å; T319-D356 WeakPolarHBondContact CG2-OD2 3.36Å; T319-D356 PolarHBondContact OG1-OD2 3.34Å; T319-K409 HydrophobicContact CG2-CG 4.08Å; T319-P412 WeakPolarHBondContact O-CA 3.37Å; T319-S415 WeakPolarHBondContact O-CB 3.09Å; T319-S415 PolarHBondContact OG1-OG 2.91Å; T319-G417 PolarHBondContact N-O 3.33Å; T319-G417 PolarHBondContact OG1-O 3.06Å; T319-I419 HydrophobicContact CG2-CD1 4.41Å; T319-I419 HydrophobicContact CG2-CG1 4.04Å
320S93Very high93.1Very high54 Ų5433.4 Ų33.438%0.37822%0.221SC..SBendtrans-78.4-2.4179.759.40000115S318 S415 G417S318-S320 PolarHBondContact OG-OG 2.75Å; S320-S415 WeakPolarHBondContact CA-O 3.05Å; S320-S415 WeakPolarHBondContact CB-O 3.19Å; S320-G417 PolarHBondContact N-O 2.83Å
321S90.1Very high94.4Very high71 Ų7132.1 Ų32.150%0.49721%0.205SC..SBendtrans-145.4162.8179.1640000111.6T319 K409T319-S321 VanDerWaalsContact C-N 3.27Å; T319-S321 PolarHBondContact O-N 2.99Å; S321-K409 WeakPolarHBondContact O-CD 3.13Å; S321-K409 WeakPolarHBondContact O-CE 3.46Å; S321-K409 PolarHBondContact O-NZ 3.28Å
322G91.3Very high95.2Very high44 Ų4430.5 Ų30.545%0.45419%0.191SC..SBendtrans89.7-163.1-175.300000113.3
323S94.8Very high95.5Very high71 Ų7134.9 Ų34.950%0.49721%0.208SC..  trans-100.8151.4-175.9-41.20000111.7E326S323-E326 VanDerWaalsContact CB-OE1 3.25Å; S323-E326 WeakPolarHBondContact CB-OE1 3.29Å; S323-E326 PolarHBondContact N-OE1 2.76Å; S323-E326 PolarHBondContact N-OE2 2.76Å; S323-E326 WeakPolarHBondContact O-CB 3.41Å; S323-E326 WeakPolarHBondContact O-CG 3.36Å; S323-E326 PolarHBondContact O-N 2.7Å; S323-E326 PolarHBondContact OG-OE1 2.91Å
324A95.1Very high95.7Very high57 Ų5734 Ų3447%0.47121%0.207SC..THydrogen-bonded Turntrans-58.9146.6169.700000110.2E326 G410A324-E326 PolarHBondContact O-N 2.92Å; A324-G410 WeakPolarHBondContact CB-O 3.39Å
325E95.6Very high95.8Very high106 Ų10634.2 Ų34.250%0.49521%0.209SC..THydrogen-bonded Turntrans69.9-0.4-177.8-56.9-68.5134.500116.1A327 R357 K409E325-A327 PolarHBondContact O-N 3.17Å; E325-R357 IonicContact OE1-CZ 2.68Å; E325-R357 IonicContact OE1-NH1 3.76Å; E325-R357 PolarHBondContact OE1-NH1 2.85Å; E325-R357 IonicContact OE1-NH2 3.95Å; E325-R357 PolarHBondContact OE1-NH2 3.26Å; E325-R357 IonicContact OE2-CZ 3.15Å; E325-R357 IonicContact OE2-NH1 3.27Å; E325-R357 IonicContact OE2-NH2 3.5Å; E325-R357 PolarHBondContact OE2-NH2 2.04Å; E325-K409 WeakPolarHBondContact CA-O 3.22Å; E325-K409 PolarHBondContact N-O 3.43Å
326E96.6Very high95.7Very high40 Ų4041.3 Ų41.319%0.18724%0.236CC..  trans-58.5134.6166.6-74.8175.6-167.900110.1D286 T287 S323 A324 T408 K409D286-E326 HydrophobicContact CB-CB 3.9Å; D286-E326 HydrophobicContact CB-CG 3.82Å; D286-E326 WeakPolarHBondContact OD2-CA 3.28Å; T287-E326 HydrophobicContact CG2-CB 4.42Å; S323-E326 VanDerWaalsContact CB-OE1 3.25Å; S323-E326 WeakPolarHBondContact CB-OE1 3.29Å; S323-E326 PolarHBondContact N-OE1 2.76Å; S323-E326 PolarHBondContact N-OE2 2.76Å; S323-E326 WeakPolarHBondContact O-CB 3.41Å; S323-E326 WeakPolarHBondContact O-CG 3.36Å; S323-E326 PolarHBondContact O-N 2.7Å; S323-E326 PolarHBondContact OG-OE1 2.91Å; A324-E326 PolarHBondContact O-N 2.92Å; E326-T408 WeakPolarHBondContact O-CA 3.47Å; E326-K409 HydrophobicContact CB-CD 4.07Å; E326-K409 HydrophobicContact CB-CG 4.42Å; E326-K409 PolarHBondContact O-N 2.81Å; E326-K409 IonicContact OE2-NZ 2.76Å; E326-K409 PolarHBondContact OE2-NZ 3.45Å
327A96.7Very high95.7Very high12 Ų1241.3 Ų41.310%0.09924%0.238CC..EExtended strand (participates in β ladder)trans-120.1150.6-178.200000112.6D286 T287 E325 Q406 G407D286-A327 PolarHBondContact N-O 3.49Å; D286-A327 VanDerWaalsContact N-O 3.15Å; D286-A327 PolarHBondContact OD2-N 3.04Å; D286-A327 VanDerWaalsContact OD2-N 3.14Å; T287-A327 PolarHBondContact N-O 3.39Å; E325-A327 PolarHBondContact O-N 3.17Å; A327-Q406 HydrophobicContact CB-CG 4.12Å; A327-G407 VanDerWaalsContact CA-O 3.22Å; A327-G407 WeakPolarHBondContact CA-O 3.45Å
328A97.6Very high95.6Very high0 Ų048 Ų480%027%0.267CS..EExtended strand (participates in β ladder)trans-125137.3168.700000110.5D285 T287 W289 L317 Q406 G407D285-A328 WeakPolarHBondContact OD2-CA 2.97Å; T287-A328 HydrophobicContact CG2-CB 4.13Å; T287-A328 WeakPolarHBondContact O-CA 3.32Å; T287-A328 WeakPolarHBondContact O-CB 3.42Å; W289-A328 HydrophobicContact CG-CB 4.31Å; W289-A328 PolarHBondContact NE1-O 3.09Å; W289-A328 VanDerWaalsContact NE1-O 3.09Å; L317-A328 HydrophobicContact CD1-CB 3.69Å; L317-A328 HydrophobicContact CD2-CB 4.06Å; L317-A328 HydrophobicContact CG-CB 4.42Å; A328-Q406 CarbonylContact O-C 3.51Å; A328-Q406 VanDerWaalsContact O-CA 3.3Å; A328-Q406 WeakPolarHBondContact O-CA 3.41Å; A328-G407 PolarHBondContact N-O 2.93Å; A328-G407 PolarHBondContact O-N 3.22Å
329L97.6Very high95.6Very high32 Ų3250.1 Ų50.117%0.16827%0.268CS..EExtended strand (participates in β ladder)trans-112.4127.6-179-61.6179.4000111.1Q281 G282 D285 F405 Q406Q281-L329 CarbonylContact C-O 3.44Å; Q281-L329 VanDerWaalsContact CA-O 3.3Å; Q281-L329 WeakPolarHBondContact CA-O 3.34Å; Q281-L329 PolarHBondContact OE1-O 2.88Å; G282-L329 PolarHBondContact N-O 3.03Å; D285-L329 HydrophobicContact CB-CD1 4.38Å; D285-L329 HydrophobicContact CB-CG 4.19Å; D285-L329 WeakPolarHBondContact OD2-CB 3.34Å; D285-L329 PolarHBondContact OD2-N 3.08Å; L329-F405 WeakPolarHBondContact CA-O 3.49Å; L329-Q406 HydrophobicContact CD2-CB 3.52Å; L329-Q406 HydrophobicContact CD2-CG 3.73Å
330L98.2Very high95.6Very high0 Ų057 Ų570%030%0.298CS..EExtended strand (participates in β ladder)trans-120.2122.8168.4-178.567.8000109F271 M279 W289 M315 L404 F405 L421F271-L330 HydrophobicContact CE1-CD2 4.39Å; F271-L330 HydrophobicContact CZ-CD2 4.24Å; M279-L330 HydrophobicContact CB-CD1 3.98Å; M279-L330 HydrophobicContact CB-CG 4.49Å; M279-L330 HydrophobicContact CE-CD2 4.06Å; M279-L330 HydrophobicContact CE-CG 3.85Å; M279-L330 HydrophobicContact SD-CD2 4.15Å; M279-L330 HydrophobicContact SD-CG 4.3Å; W289-L330 HydrophobicContact CD2-CB 4.5Å; W289-L330 HydrophobicContact CG-CB 4.05Å; M315-L330 HydrophobicContact CB-CD2 4.12Å; M315-L330 HydrophobicContact CE-CD1 4.23Å; M315-L330 HydrophobicContact CE-CD2 4.33Å; M315-L330 HydrophobicContact CG-CD2 3.77Å; L330-L404 CarbonylContact O-C 3.54Å; L330-L404 VanDerWaalsContact O-CA 3.31Å; L330-L404 WeakPolarHBondContact O-CA 3.32Å; L330-F405 PolarHBondContact N-O 3.37Å; L330-F405 PolarHBondContact O-N 2.84Å; L330-L421 HydrophobicContact CD2-CD1 4.48Å
331E97.4Very high95.7Very high9 Ų957.9 Ų57.94%0.04230%0.296CS..EExtended strand (participates in β ladder)trans-119.2138-174.5-42.1-165.7-159.900112.5M279 I280 R363 L404M279-E331 CarbonylContact C-O 3.51Å; M279-E331 WeakPolarHBondContact CA-O 3.32Å; M279-E331 WeakPolarHBondContact CB-O 3.46Å; I280-E331 HydrophobicContact CD1-CB 4.49Å; I280-E331 HydrophobicContact CG1-CB 3.81Å; I280-E331 HydrophobicContact CG1-CG 4.32Å; I280-E331 PolarHBondContact N-O 3.03Å; I280-E331 PolarHBondContact O-N 3.32Å; E331-R363 IonicContact OE1-CZ 3.86Å; E331-R363 IonicContact OE1-NH1 2.67Å; E331-R363 PolarHBondContact OE1-NH1 3.27Å; E331-R363 IonicContact OE1-NH2 2.87Å; E331-R363 PolarHBondContact OE1-NH2 2.94Å; E331-R363 IonicContact OE2-CZ 3.14Å; E331-R363 IonicContact OE2-NE 2.76Å; E331-R363 IonicContact OE2-NH1 2.67Å; E331-R363 PolarHBondContact OE2-NH1 3.31Å; E331-R363 IonicContact OE2-NH2 2.74Å; E331-R363 PolarHBondContact OE2-NH2 2.85Å; E331-L404 HydrophobicContact CB-CD2 4.36Å; E331-L404 HydrophobicContact CB-CG 3.99Å; E331-L404 HydrophobicContact CG-CB 4.26Å; E331-L404 HydrophobicContact CG-CD2 3.51Å; E331-L404 HydrophobicContact CG-CG 3.66Å; E331-L404 WeakPolarHBondContact OE2-CD2 3.33Å
332S98.3Very high96.1Very high0 Ų054.5 Ų54.50%027%0.272CS..PPolyproline II helixtrans-61.9162.4167.854.70000112.5R402 Y403S332-R402 WeakPolarHBondContact O-CD 3.33Å; S332-R402 WeakPolarHBondContact O-CG 3.22Å; S332-R402 PolarHBondContact O-NH1 2.91Å; S332-R402 WeakPolarHBondContact OG-CA 3.44Å; S332-Y403 VanDerWaalsContact CB-CE1 3.46Å; S332-Y403 PolarHBondContact N-O 2.8Å; S332-Y403 WeakPolarHBondContact OG-CD1 3.39Å; S332-Y403 PolarHBondContact OG-N 3.24Å; S332-Y403 PolarHBondContact OG-O 3.24Å
333R96.9Very high96.4Very high92 Ų9252.6 Ų52.635%0.34725%0.252SS..PPolyproline II helixtrans-61.4173.3163.569.3174.7-179.4-74.5-11110.8L266 D267 C277 L335L266-R333 PolarHBondContact O-NH2 2.9Å; D267-R333 VanDerWaalsContact CG-NH1 3.32Å; D267-R333 IonicContact OD1-CZ 2.7Å; D267-R333 IonicContact OD1-NH1 3.63Å; D267-R333 PolarHBondContact OD1-NH1 2.8Å; D267-R333 IonicContact OD1-NH2 3.13Å; D267-R333 PolarHBondContact OD1-NH2 3.26Å; D267-R333 IonicContact OD2-CZ 3.18Å; D267-R333 IonicContact OD2-NH1 3.49Å; D267-R333 PolarHBondContact OD2-NH1 2.83Å; D267-R333 IonicContact OD2-NH2 3.98Å; C277-R333 PolarHBondContact O-NH1 2.73Å; R333-L335 HydrophobicContact CG-CD2 4.15Å; R333-L335 PolarHBondContact O-N 3.27Å
334I96.8Very high96.6Very high55 Ų5549.2 Ų49.228%0.28223%0.228SC..PPolyproline II helixtrans-69.6126.4171.5-61.2175.8000109.1Y336 V371 K400 R402I334-Y336 HydrophobicContact CB-CE2 4.48Å; I334-Y336 HydrophobicContact CG2-CE1 4.44Å; I334-Y336 HydrophobicContact CG2-CE2 3.9Å; I334-V371 HydrophobicContact CD1-CG2 4.46Å; I334-K400 HydrophobicContact CG2-CB 3.85Å; I334-K400 HydrophobicContact CG2-CD 4.19Å; I334-K400 HydrophobicContact CG2-CG 4.3Å; I334-R402 HydrophobicContact CG1-CG 4.34Å
335L97Very high96.7Very high5 Ų547.3 Ų47.33%0.02621%0.21CC..BIsolated β-bridgetrans-110.8151.9-179.5-62.2163.2000109.9D267 R333 K400 F401 Y403 L426D267-L335 HydrophobicContact CB-CD1 4.42Å; D267-L335 HydrophobicContact CB-CD2 3.95Å; R333-L335 HydrophobicContact CG-CD2 4.15Å; R333-L335 PolarHBondContact O-N 3.27Å; L335-K400 CarbonylContact O-C 3.52Å; L335-K400 WeakPolarHBondContact O-CA 3.33Å; L335-K400 WeakPolarHBondContact O-CB 3.27Å; L335-F401 HydrophobicContact CB-CE1 4.3Å; L335-F401 HydrophobicContact CD1-CE2 4.49Å; L335-F401 HydrophobicContact CD1-CZ 4.5Å; L335-F401 PolarHBondContact N-O 2.81Å; L335-F401 PolarHBondContact O-N 3.2Å; L335-F401 VanDerWaalsContact O-N 3.08Å; L335-Y403 HydrophobicContact CD1-CD1 3.66Å; L335-Y403 HydrophobicContact CD1-CE1 3.63Å; L335-L426 HydrophobicContact CD1-CD2 3.55Å
336Y95.5Very high96.8Very high150 Ų15042.3 Ų42.359%0.58819%0.186SC*.  trans-126.289.8-172.6-63-94.2000109.4L266 I334 K400L266-Y336 WeakPolarHBondContact CD2-O 3.34Å; I334-Y336 HydrophobicContact CB-CE2 4.48Å; I334-Y336 HydrophobicContact CG2-CE1 4.44Å; I334-Y336 HydrophobicContact CG2-CE2 3.9Å; Y336-K400 HydrophobicContact CD1-CB 3.85Å; Y336-K400 HydrophobicContact CE1-CB 3.9Å; Y336-K400 HydrophobicContact CE1-CD 4.05Å
337P95.4Very high96.9Very high21 Ų2140.6 Ų40.614%0.13618%0.178CC..  trans-67144.5-179.128.4-33.4000111L266 E397 Q399 F401 E428L266-P337 HydrophobicContact CD1-CB 4.27Å; P337-E397 WeakPolarHBondContact CB-O 3.4Å; P337-E397 HydrophobicContact CG-CB 4.44Å; P337-E397 VanDerWaalsContact CG-O 3.32Å; P337-E397 WeakPolarHBondContact CG-O 3.37Å; P337-Q399 WeakPolarHBondContact CD-O 3.31Å; P337-Q399 VanDerWaalsContact CG-O 3.29Å; P337-Q399 WeakPolarHBondContact CG-O 3.31Å; P337-F401 HydrophobicContact CB-CE1 4.18Å; P337-F401 HydrophobicContact CG-CD1 3.99Å; P337-F401 HydrophobicContact CG-CE1 3.91Å; P337-E428 VanDerWaalsContact CA-OE1 3.22Å; P337-E428 WeakPolarHBondContact CA-OE1 3.34Å; P337-E428 VanDerWaalsContact CB-OE1 3.25Å; P337-E428 WeakPolarHBondContact CB-OE1 3.37Å
338K93.4Very high96.9Very high140 Ų14041 Ų4161%0.60918%0.178SC*.SBendtrans-107.9-16.6173-57.7174.3-176.8169.10111.8E428K338-E428 WeakPolarHBondContact CB-OE2 3.5Å; K338-E428 VanDerWaalsContact N-CD 3.25Å; K338-E428 PolarHBondContact N-OE1 3.09Å; K338-E428 PolarHBondContact N-OE2 3.23Å
339R94.6Very high96.7Very high93 Ų9342.4 Ų42.435%0.35118%0.184SC..SBendtrans-119173.3175.7-53.3176.878.1178.918.5110E100 Q342 E428E100-R339 IonicContact OE1-CZ 2.73Å; E100-R339 IonicContact OE1-NH1 3.42Å; E100-R339 PolarHBondContact OE1-NH1 3.06Å; E100-R339 IonicContact OE1-NH2 3.53Å; E100-R339 PolarHBondContact OE1-NH2 2.84Å; E100-R339 IonicContact OE2-CZ 3.59Å; E100-R339 IonicContact OE2-NH1 3.99Å; E100-R339 PolarHBondContact OE2-NH1 2.85Å; E100-R339 IonicContact OE2-NH2 3.73Å; R339-Q342 PolarHBondContact O-NE2 2.91Å; R339-E428 HydrophobicContact CB-CB 4.07Å; R339-E428 WeakPolarHBondContact CD-O 3.43Å; R339-E428 HydrophobicContact CG-CB 4.15Å; R339-E428 PolarHBondContact N-OE1 3.24Å; R339-E428 PolarHBondContact NH1-O 2.82Å
340K94.8Very high96.6Very high145 Ų14541 Ų4163%0.6318%0.176SC*.SBendtrans-91.1-7.5-171.3-58.8-175.2174-174.40114.4K396 E398K340-K396 VanDerWaalsContact O-CA 3.31Å; K340-K396 WeakPolarHBondContact O-CA 3.43Å; K340-E398 HydrophobicContact CB-CG 4.33Å; K340-E398 WeakPolarHBondContact CD-OE1 3.47Å; K340-E398 HydrophobicContact CG-CG 4.14Å
341Q95.6Very high96.4Very high72 Ų7242.2 Ų42.234%0.33618%0.184SC..  trans-141.8139.9-174.9-178.3172.3-400109V394 L395 E428Q341-V394 HydrophobicContact CG-CG1 4.23Å; Q341-L395 WeakPolarHBondContact CA-O 3.29Å; Q341-E428 CarbonylContact O-C 3.56Å; Q341-E428 WeakPolarHBondContact O-CA 3.33Å
342Q97.9Very high96.2Very high0 Ų042.2 Ų42.20%019%0.186CC..EExtended strand (participates in β ladder)trans-132.9154177-53.777.731.800110.3L266 R339 L395 E397 L426 T427 E428 T429L266-Q342 HydrophobicContact CD1-CG 3.88Å; R339-Q342 PolarHBondContact O-NE2 2.91Å; Q342-L395 HydrophobicContact CB-CB 4.22Å; Q342-L395 PolarHBondContact N-O 3.37Å; Q342-L395 PolarHBondContact O-N 2.77Å; Q342-L395 PolarHBondContact OE1-O 2.88Å; Q342-E397 PolarHBondContact NE2-O 2.7Å; Q342-L426 HydrophobicContact CB-CD1 3.83Å; Q342-T427 CarbonylContact C-O 3.52Å; Q342-T427 WeakPolarHBondContact CA-O 3.15Å; Q342-T427 VanDerWaalsContact CB-O 3.29Å; Q342-T427 WeakPolarHBondContact CB-O 3.49Å; Q342-E428 HydrophobicContact CG-CG 4.12Å; Q342-E428 PolarHBondContact NE2-OE1 3.21Å; Q342-T429 CarbonylContact C-O 3.47Å
343C98.2Very high96Very high4 Ų442.5 Ų42.53%0.02719%0.188CC..EExtended strand (participates in β ladder)trans-114.8113.9168.9-1690000109.5T427 T429 C431C343-T427 PolarHBondContact N-O 3.38Å; C343-T427 PolarHBondContact O-N 2.05Å; C343-T429 WeakPolarHBondContact CB-O 3.47Å; C343-T429 PolarHBondContact N-O 2.78Å; C343-C431 WeakPolarHBondContact CA-SG 3.46Å; C343-C431 HydrophobicContact CB-CB 4Å; C343-C431 WeakPolarHBondContact CB-SG 3.14Å; C343-C431 WeakPolarHBondContact SG-CA 3.46Å; C343-C431 WeakPolarHBondContact SG-CB 3.27Å; C343-C431 CovalentContact SG-SG 2.04Å; C343-C431 PolarHBondContact SG-SG 3.19Å
344L98.6Very high95.8Very high0 Ų040.9 Ų40.90%019%0.189CC..EExtended strand (participates in β ladder)trans-88.7108.9169.3177.464.9000108.2F346 V360 H392 V393 L395 Y403 F405 I424 L426L344-F346 HydrophobicContact CD2-CD1 4.36Å; L344-F346 HydrophobicContact CD2-CE1 4.28Å; L344-F346 HydrophobicContact CG-CD1 3.98Å; L344-F346 HydrophobicContact CG-CE1 4.27Å; L344-V360 HydrophobicContact CD2-CG1 3.88Å; L344-H392 CarbonylContact O-C 3.54Å; L344-H392 WeakPolarHBondContact O-CA 3.25Å; L344-V393 HydrophobicContact CB-CB 4.27Å; L344-V393 PolarHBondContact N-O 2.87Å; L344-V393 PolarHBondContact O-N 2.8Å; L344-L395 HydrophobicContact CB-CD1 4.15Å; L344-L395 HydrophobicContact CB-CG 4.36Å; L344-Y403 HydrophobicContact CD1-CD1 4.28Å; L344-Y403 HydrophobicContact CD1-CD2 4.23Å; L344-Y403 HydrophobicContact CD1-CE1 4.18Å; L344-Y403 HydrophobicContact CD1-CE2 4.16Å; L344-Y403 HydrophobicContact CD1-CG 4.29Å; L344-Y403 HydrophobicContact CD2-CD2 4.04Å; L344-Y403 HydrophobicContact CD2-CG 4.1Å; L344-F405 HydrophobicContact CD2-CE1 4.46Å; L344-F405 HydrophobicContact CD2-CZ 4.24Å; L344-I424 HydrophobicContact CD1-CG2 3.79Å; L344-L426 HydrophobicContact CB-CD1 3.85Å; L344-L426 HydrophobicContact CD1-CB 4.25Å; L344-L426 HydrophobicContact CD1-CD1 4.23Å
345Q98.4Very high95.7Very high18 Ų1841 Ų418%0.08420%0.195CC..EExtended strand (participates in β ladder)trans-102.7139.6172.8-175.3-168.2-52.300109.5I390 A391 H392 I424 T425Q345-I390 HydrophobicContact CG-CD1 3.89Å; Q345-I390 HydrophobicContact CG-CG1 3.94Å; Q345-A391 VanDerWaalsContact CA-O 3.27Å; Q345-A391 WeakPolarHBondContact CA-O 3.4Å; Q345-H392 PolarHBondContact OE1-NE2 2.8Å; Q345-I424 CarbonylContact O-C 3.56Å; Q345-I424 WeakPolarHBondContact O-CA 3.37Å; Q345-T425 PolarHBondContact N-O 3.15Å; Q345-T425 PolarHBondContact O-N 3.45Å
346F98.3Very high95.7Very high0 Ų040.8 Ų40.80%019%0.194CC..EExtended strand (participates in β ladder)trans-158.2157.9170.955.3-83.7000110.4L344 Y348 L358 V360 F380 A391 V393 F405 L421 I424L344-F346 HydrophobicContact CD2-CD1 4.36Å; L344-F346 HydrophobicContact CD2-CE1 4.28Å; L344-F346 HydrophobicContact CG-CD1 3.98Å; L344-F346 HydrophobicContact CG-CE1 4.27Å; F346-Y348 HydrophobicContact CD2-CD1 4.39Å; F346-Y348 AromaticContact CE2-CD1 4Å; F346-Y348 HydrophobicContact CE2-CD1 4Å; F346-Y348 HydrophobicContact CE2-CG 4.26Å; F346-L358 HydrophobicContact CE2-CD2 3.8Å; F346-L358 HydrophobicContact CZ-CD2 4.42Å; F346-V360 HydrophobicContact CE1-CG2 4.09Å; F346-V360 HydrophobicContact CZ-CG2 3.92Å; F346-F380 HydrophobicContact CZ-CD2 4.45Å; F346-F380 AromaticContact CZ-CE2 3.79Å; F346-F380 HydrophobicContact CZ-CE2 3.79Å; F346-F380 HydrophobicContact CZ-CZ 4.14Å; F346-A391 HydrophobicContact CD1-CB 4.28Å; F346-A391 HydrophobicContact CD2-CB 4.15Å; F346-A391 HydrophobicContact CE1-CB 3.79Å; F346-A391 HydrophobicContact CE2-CB 3.63Å; F346-A391 HydrophobicContact CG-CB 4.45Å; F346-A391 HydrophobicContact CZ-CB 3.44Å; F346-A391 VanDerWaalsContact CZ-CB 3.44Å; F346-A391 PolarHBondContact N-O 2.93Å; F346-A391 VanDerWaalsContact N-O 3.16Å; F346-A391 PolarHBondContact O-N 3.42Å; F346-V393 HydrophobicContact CE1-CG2 3.88Å; F346-V393 HydrophobicContact CZ-CG2 4.38Å; F346-F405 HydrophobicContact CB-CZ 4.41Å; F346-F405 AromaticContact CD1-CE1 3.75Å; F346-F405 HydrophobicContact CD1-CE1 3.75Å; F346-F405 AromaticContact CD1-CZ 3.84Å; F346-F405 HydrophobicContact CD1-CZ 3.84Å; F346-F405 AromaticContact CD2-CE1 4Å; F346-F405 HydrophobicContact CD2-CE1 4Å; F346-F405 HydrophobicContact CD2-CZ 4.36Å; F346-F405 AromaticContact CE1-CE1 3.63Å; F346-F405 HydrophobicContact CE1-CE1 3.63Å; F346-F405 HydrophobicContact CE1-CZ 4.17Å; F346-F405 AromaticContact CE2-CE1 3.89Å; F346-F405 HydrophobicContact CE2-CE1 3.89Å; F346-F405 AromaticContact CG-CE1 3.94Å; F346-F405 HydrophobicContact CG-CE1 3.94Å; F346-F405 AromaticContact CG-CZ 3.94Å; F346-F405 HydrophobicContact CG-CZ 3.94Å; F346-F405 AromaticContact CZ-CE1 3.7Å; F346-F405 HydrophobicContact CZ-CE1 3.7Å; F346-L421 HydrophobicContact CD2-CD2 3.88Å; F346-L421 HydrophobicContact CE2-CD2 4.12Å; F346-I424 HydrophobicContact CB-CB 4.3Å; F346-I424 HydrophobicContact CB-CG1 3.81Å; F346-I424 HydrophobicContact CB-CG2 4.45Å
347F97.8Very high95.8Very high4 Ų436.3 Ų36.32%0.01818%0.176CC..EExtended strand (participates in β ladder)trans-94.1137.5168.6-75.2-96.6000109.7H302 W388 K389 I390 D422 D423 I588H302-F347 HydrophobicContact CB-CB 4.27Å; H302-F347 AromaticContact CD2-CD1 3.7Å; H302-F347 AromaticContact CE1-CD1 3.45Å; H302-F347 VanDerWaalsContact CE1-CD1 3.45Å; H302-F347 WeakPolarHBondContact CE1-CD1 3.49Å; H302-F347 AromaticContact CE1-CD2 3.7Å; H302-F347 AromaticContact CE1-CE1 3.3Å; H302-F347 WeakPolarHBondContact CE1-CE1 3.37Å; H302-F347 AromaticContact CE1-CE2 3.55Å; H302-F347 AromaticContact CE1-CG 3.63Å; H302-F347 AromaticContact CE1-CZ 3.34Å; H302-F347 WeakPolarHBondContact CE1-CZ 3.25Å; H302-F347 AromaticContact CG-CD1 3.96Å; H302-F347 AromaticContact CG-CG 3.86Å; H302-F347 AromaticContact ND1-CD1 3.82Å; H302-F347 AromaticContact ND1-CD2 3.66Å; H302-F347 AromaticContact ND1-CE2 3.94Å; H302-F347 AromaticContact ND1-CG 3.58Å; H302-F347 AromaticContact NE2-CD1 3.38Å; H302-F347 WeakPolarHBondContact NE2-CD1 3.33Å; H302-F347 AromaticContact NE2-CE1 3.29Å; H302-F347 VanDerWaalsContact NE2-CE1 3.29Å; H302-F347 WeakPolarHBondContact NE2-CE1 3.25Å; H302-F347 AromaticContact NE2-CG 3.97Å; H302-F347 AromaticContact NE2-CZ 3.82Å; F347-W388 HydrophobicContact CB-CE3 3.9Å; F347-W388 HydrophobicContact CB-CZ3 4.21Å; F347-K389 CarbonylContact C-O 3.57Å; F347-K389 VanDerWaalsContact CA-O 3.28Å; F347-K389 WeakPolarHBondContact CA-O 3.48Å; F347-I390 HydrophobicContact CD1-CB 4.16Å; F347-I390 HydrophobicContact CE1-CB 3.82Å; F347-I390 HydrophobicContact CE1-CD1 4.44Å; F347-I390 HydrophobicContact CE1-CG1 4.35Å; F347-I390 HydrophobicContact CE2-CD1 4.01Å; F347-I390 HydrophobicContact CE2-CG1 4.24Å; F347-I390 HydrophobicContact CZ-CB 4.05Å; F347-I390 HydrophobicContact CZ-CD1 3.8Å; F347-I390 HydrophobicContact CZ-CG1 4.11Å; F347-D422 PolarHBondContact N-O 2.92Å; F347-D422 PolarHBondContact O-N 3.47Å; F347-D423 HydrophobicContact CB-CB 4.48Å; F347-D423 HydrophobicContact CD2-CB 3.68Å; F347-D423 HydrophobicContact CE2-CB 4.41Å; F347-D423 HydrophobicContact CG-CB 4.47Å; F347-I588 HydrophobicContact CE1-CD1 3.86Å; F347-I588 HydrophobicContact CZ-CD1 4.02Å
348Y96.8Very high96Very high22 Ų2235.3 Ų35.39%0.08617%0.169CC..EExtended strand (participates in β ladder)trans-138.4152.717677.3-78.2000111.2F346 M350 L358 F380 W388 K389 A391 Y420F346-Y348 HydrophobicContact CD2-CD1 4.39Å; F346-Y348 AromaticContact CE2-CD1 4Å; F346-Y348 HydrophobicContact CE2-CD1 4Å; F346-Y348 HydrophobicContact CE2-CG 4.26Å; Y348-M350 HydrophobicContact CD2-CE 4.12Å; Y348-M350 HydrophobicContact CD2-CG 4.35Å; Y348-M350 HydrophobicContact CE2-CE 4.21Å; Y348-M350 HydrophobicContact CE2-SD 4.46Å; Y348-L358 HydrophobicContact CD2-CD2 4.24Å; Y348-L358 HydrophobicContact CG-CD2 4.17Å; Y348-F380 HydrophobicContact CE1-CD1 4.19Å; Y348-F380 HydrophobicContact CE2-CB 4.27Å; Y348-F380 AromaticContact CZ-CD1 3.95Å; Y348-W388 VanDerWaalsContact C-CE3 3.43Å; Y348-K389 HydrophobicContact CD1-CB 4.1Å; Y348-K389 WeakPolarHBondContact CD1-O 3.45Å; Y348-K389 HydrophobicContact CE1-CB 3.61Å; Y348-K389 HydrophobicContact CE2-CB 4.49Å; Y348-K389 PolarHBondContact N-O 3.32Å; Y348-K389 PolarHBondContact O-N 3.41Å; Y348-A391 HydrophobicContact CD1-CB 3.91Å; Y348-A391 HydrophobicContact CE1-CB 3.85Å; Y348-Y420 WeakPolarHBondContact CA-O 3.31Å; Y348-Y420 WeakPolarHBondContact CB-O 3.43Å
349K93.8Very high96.2Very high29 Ų2929 Ų2913%0.12614%0.142CC..EExtended strand (participates in β ladder)trans-137.4145.6175.6-179.7-171.8-176-171.70108.4G298 T351 H386 W388 Y420G298-K349 PolarHBondContact O-NZ 3.38Å; K349-T351 HydrophobicContact CD-CG2 4.15Å; K349-T351 HydrophobicContact CG-CG2 4.1Å; K349-H386 WeakPolarHBondContact CE-O 3.13Å; K349-H386 VanDerWaalsContact CG-O 3.25Å; K349-H386 WeakPolarHBondContact CG-O 3.19Å; K349-W388 HydrophobicContact CB-CD2 3.81Å; K349-W388 HydrophobicContact CB-CE3 3.76Å; K349-W388 HydrophobicContact CB-CG 4.32Å; K349-W388 HydrophobicContact CB-CH2 4.49Å; K349-W388 HydrophobicContact CB-CZ3 4.12Å; K349-W388 HydrophobicContact CD-CD2 4.37Å; K349-W388 HydrophobicContact CD-CG 4.48Å; K349-Y420 HydrophobicContact CB-CD2 4.22Å; K349-Y420 HydrophobicContact CB-CG 4.37Å; K349-Y420 HydrophobicContact CD-CD2 4.47Å; K349-Y420 HydrophobicContact CG-CD2 4.36Å; K349-Y420 PolarHBondContact N-O 2.85Å; K349-Y420 VanDerWaalsContact N-O 3.09Å; K349-Y420 WeakPolarHBondContact O-CD2 3.35Å; K349-Y420 PolarHBondContact O-N 3.14Å
350M94.8Very high96.4Very high3 Ų324.6 Ų24.62%0.01513%0.125CC..EExtended strand (participates in β ladder)trans-131.7115.1175.5-68.2179.4179.300109.1Y348 L358 F380 G382 H386 G418 I419Y348-M350 HydrophobicContact CD2-CE 4.12Å; Y348-M350 HydrophobicContact CD2-CG 4.35Å; Y348-M350 HydrophobicContact CE2-CE 4.21Å; Y348-M350 HydrophobicContact CE2-SD 4.46Å; M350-L358 HydrophobicContact CE-CB 3.19Å; M350-L358 HydrophobicContact CE-CD2 4.37Å; M350-L358 HydrophobicContact CE-CG 4.41Å; M350-F380 HydrophobicContact CE-CB 4.27Å; M350-G382 WeakPolarHBondContact SD-CA 3.24Å; M350-H386 PolarHBondContact O-ND1 2.82Å; M350-G418 CarbonylContact C-O 3.59Å; M350-G418 WeakPolarHBondContact CA-O 3.48Å; M350-I419 HydrophobicContact CE-CD1 4.45Å; M350-I419 HydrophobicContact CE-CG2 4.03Å; M350-I419 HydrophobicContact CG-CG1 4.31Å; M350-I419 HydrophobicContact CG-CG2 4.15Å
351T93.9Very high96.5Very high25 Ų2519.9 Ų19.915%0.15310%0.104CC..  trans-112.22178.163.50000112.9K349 H386 G417 G418 Y420K349-T351 HydrophobicContact CD-CG2 4.15Å; K349-T351 HydrophobicContact CG-CG2 4.1Å; T351-H386 HydrophobicContact CG2-CB 4.21Å; T351-G417 VanDerWaalsContact OG1-CA 3.31Å; T351-G417 WeakPolarHBondContact OG1-CA 3.36Å; T351-G418 PolarHBondContact N-O 3.38Å; T351-G418 PolarHBondContact OG1-N 2.93Å; T351-G418 VanDerWaalsContact OG1-N 3.12Å; T351-Y420 HydrophobicContact CG2-CE2 4.09Å; T351-Y420 VanDerWaalsContact OG1-CE2 3.28Å; T351-Y420 WeakPolarHBondContact OG1-CE2 3.48Å; T351-Y420 PolarHBondContact OG1-OH 3.04Å
352G93Very high96.6Very high8 Ų816.5 Ų16.58%0.0829%0.088CC..SBendtrans-84.9-145.1177.100000113.5D356 S415G352-D356 WeakPolarHBondContact CA-OD2 3.4Å; G352-S415 WeakPolarHBondContact CA-OG 3.22Å
353S93.8Very high96.6Very high6 Ų619.3 Ų19.34%0.04210%0.098CC..  trans-75.7146.2179.6173.40000111S355 D356 S415S353-S355 PolarHBondContact O-N 2.87Å; S353-S355 WeakPolarHBondContact OG-CB 3.41Å; S353-S355 PolarHBondContact OG-N 3.36Å; S353-S355 VanDerWaalsContact OG-N 3.08Å; S353-D356 PolarHBondContact N-OD2 3.39Å; S353-D356 WeakPolarHBondContact O-CB 3.2Å; S353-D356 VanDerWaalsContact O-CG 3.31Å; S353-D356 PolarHBondContact O-N 2.82Å; S353-S415 PolarHBondContact N-OG 2.83Å
354P93.9Very high96.4Very high59 Ų5922.7 Ų22.738%0.38311%0.111SC..THydrogen-bonded Turntrans-57.3-17.1167.2-25.835.4000113.7D356 Q381 D384P354-D356 VanDerWaalsContact C-N 3.34Å; P354-Q381 WeakPolarHBondContact O-CG 3.37Å; P354-Q381 PolarHBondContact O-NE2 3.48Å; P354-D384 WeakPolarHBondContact CG-OD1 3.46Å
355S95.1Very high96Very high57 Ų5723.6 Ų23.640%0.39912%0.115SC..THydrogen-bonded Turntrans-80.5-12.3174.2-60.30000113.7S353 Q381 G410S353-S355 PolarHBondContact O-N 2.87Å; S353-S355 WeakPolarHBondContact OG-CB 3.41Å; S353-S355 PolarHBondContact OG-N 3.36Å; S353-S355 VanDerWaalsContact OG-N 3.08Å; S355-Q381 VanDerWaalsContact C-NE2 3.25Å; S355-Q381 PolarHBondContact O-NE2 3.47Å; S355-G410 WeakPolarHBondContact O-CA 3.44Å
356D96.4Very high95.5Very high0 Ų024.8 Ų24.80%012%0.123CC..  trans-65.2149.3176.8-65.1-17.8000110.7T319 G352 S353 P354 Q381 G382 G410 I419T319-D356 VanDerWaalsContact CB-OD2 3.26Å; T319-D356 WeakPolarHBondContact CB-OD2 3.48Å; T319-D356 WeakPolarHBondContact CG2-OD2 3.36Å; T319-D356 PolarHBondContact OG1-OD2 3.34Å; G352-D356 WeakPolarHBondContact CA-OD2 3.4Å; S353-D356 PolarHBondContact N-OD2 3.39Å; S353-D356 WeakPolarHBondContact O-CB 3.2Å; S353-D356 VanDerWaalsContact O-CG 3.31Å; S353-D356 PolarHBondContact O-N 2.82Å; P354-D356 VanDerWaalsContact C-N 3.34Å; D356-Q381 PolarHBondContact O-NE2 2.96Å; D356-Q381 VanDerWaalsContact O-NE2 3.16Å; D356-G382 PolarHBondContact O-N 3.3Å; D356-G410 PolarHBondContact OD1-N 2.87Å; D356-I419 HydrophobicContact CB-CD1 4.29Å; D356-I419 HydrophobicContact CB-CG1 4.46Å
357R97.6Very high94.9Very high57 Ų5729.9 Ų29.922%0.21516%0.158CC..EExtended strand (participates in β ladder)trans-135.8136.4-174.5-57.4-178.5-57.4-104.54.2111.4E325 I359 T379 F380 G407 T408 I419E325-R357 IonicContact OE1-CZ 2.68Å; E325-R357 IonicContact OE1-NH1 3.76Å; E325-R357 PolarHBondContact OE1-NH1 2.85Å; E325-R357 IonicContact OE1-NH2 3.95Å; E325-R357 PolarHBondContact OE1-NH2 3.26Å; E325-R357 IonicContact OE2-CZ 3.15Å; E325-R357 IonicContact OE2-NH1 3.27Å; E325-R357 IonicContact OE2-NH2 3.5Å; E325-R357 PolarHBondContact OE2-NH2 2.04Å; R357-I359 HydrophobicContact CB-CG1 4.5Å; R357-T379 HydrophobicContact CB-CG2 4.36Å; R357-F380 WeakPolarHBondContact CA-O 3.49Å; R357-G407 CarbonylContact O-C 3.55Å; R357-G407 WeakPolarHBondContact O-CA 3.13Å; R357-T408 PolarHBondContact N-O 3.09Å; R357-T408 VanDerWaalsContact NH2-CG2 3.35Å; R357-T408 PolarHBondContact O-N 3.04Å; R357-I419 WeakPolarHBondContact O-CD1 3.46Å
358L98.4Very high94.4Very high0 Ų034.1 Ų34.10%019%0.185CC..EExtended strand (participates in β ladder)trans-110.5122.4165.7173.967.5000108.6W289 F346 Y348 M350 T379 F380 F405 Q406 I419 L421W289-L358 HydrophobicContact CH2-CD1 4.14Å; W289-L358 HydrophobicContact CZ2-CD1 4.1Å; F346-L358 HydrophobicContact CE2-CD2 3.8Å; F346-L358 HydrophobicContact CZ-CD2 4.42Å; Y348-L358 HydrophobicContact CD2-CD2 4.24Å; Y348-L358 HydrophobicContact CG-CD2 4.17Å; M350-L358 HydrophobicContact CE-CB 3.19Å; M350-L358 HydrophobicContact CE-CD2 4.37Å; M350-L358 HydrophobicContact CE-CG 4.41Å; L358-T379 CarbonylContact O-C 3.42Å; L358-T379 WeakPolarHBondContact O-CA 3.47Å; L358-F380 HydrophobicContact CB-CB 4.3Å; L358-F380 HydrophobicContact CD2-CD2 4.39Å; L358-F380 HydrophobicContact CG-CD2 4.45Å; L358-F380 PolarHBondContact N-O 3.49Å; L358-F380 PolarHBondContact O-N 3.17Å; L358-F405 HydrophobicContact CD1-CB 4.06Å; L358-F405 HydrophobicContact CD1-CD1 4.09Å; L358-Q406 CarbonylContact C-O 3.59Å; L358-Q406 WeakPolarHBondContact CA-O 3.45Å; L358-I419 HydrophobicContact CB-CG2 4.28Å; L358-I419 HydrophobicContact CD1-CG2 4.43Å; L358-L421 HydrophobicContact CD1-CD1 4.42Å; L358-L421 HydrophobicContact CD1-CD2 4.26Å; L358-L421 HydrophobicContact CD2-CD2 3.7Å
359I98.4Very high93.8Very high7 Ų734.6 Ų34.64%0.03620%0.196CC..EExtended strand (participates in β ladder)trans-118.4127.3-176.5-53.4163000108.9R357 W361 K376 Q378 T379 Q406R357-I359 HydrophobicContact CB-CG1 4.5Å; I359-W361 HydrophobicContact CG2-CD2 4.31Å; I359-W361 HydrophobicContact CG2-CG 4.38Å; I359-W361 HydrophobicContact CG2-CZ2 4.02Å; I359-K376 HydrophobicContact CG2-CD 4.1Å; I359-K376 VanDerWaalsContact CG2-CE 3.5Å; I359-K376 HydrophobicContact CG2-CG 3.79Å; I359-Q378 CarbonylContact C-O 3.41Å; I359-Q378 WeakPolarHBondContact CA-O 3.41Å; I359-Q378 WeakPolarHBondContact CG2-O 3.35Å; I359-T379 HydrophobicContact CG1-CG2 3.89Å; I359-Q406 HydrophobicContact CB-CB 4.19Å; I359-Q406 PolarHBondContact N-O 3.27Å; I359-Q406 PolarHBondContact O-N 3.04Å
360V98.6Very high93.6Very high0 Ų036.5 Ų36.50%021%0.208CC..EExtended strand (participates in β ladder)trans-92.9127.51721790000109.2L344 F346 V377 Q378 F380 V393 L404 F405L344-V360 HydrophobicContact CD2-CG1 3.88Å; F346-V360 HydrophobicContact CE1-CG2 4.09Å; F346-V360 HydrophobicContact CZ-CG2 3.92Å; V360-V377 HydrophobicContact CG1-CB 4.49Å; V360-V377 WeakPolarHBondContact O-CB 3.26Å; V360-V377 PolarHBondContact O-N 2.85Å; V360-Q378 PolarHBondContact N-O 3.04Å; V360-Q378 PolarHBondContact O-N 2.91Å; V360-F380 HydrophobicContact CG2-CE2 4.03Å; V360-V393 HydrophobicContact CG1-CG1 4.2Å; V360-V393 HydrophobicContact CG2-CG2 4.27Å; V360-L404 WeakPolarHBondContact CA-O 3.12Å; V360-F405 HydrophobicContact CG2-CD1 3.97Å; V360-F405 HydrophobicContact CG2-CE1 3.92Å
361W98.1Very high93.5Very high47 Ų4737.5 Ų37.518%0.17821%0.214CC..EExtended strand (participates in β ladder)trans-120.1158.6175-57.783.6000110.9I359 L374 V375 K376 Y403 L404I359-W361 HydrophobicContact CG2-CD2 4.31Å; I359-W361 HydrophobicContact CG2-CG 4.38Å; I359-W361 HydrophobicContact CG2-CZ2 4.02Å; W361-L374 HydrophobicContact CB-CD1 3.94Å; W361-L374 HydrophobicContact CB-CG 4.37Å; W361-L374 HydrophobicContact CD2-CD2 4.1Å; W361-L374 HydrophobicContact CD2-CG 4.23Å; W361-L374 HydrophobicContact CE3-CD1 4.45Å; W361-L374 HydrophobicContact CE3-CD2 3.7Å; W361-L374 HydrophobicContact CE3-CG 3.64Å; W361-L374 HydrophobicContact CG-CD1 4.49Å; W361-L374 HydrophobicContact CZ3-CD2 4.04Å; W361-L374 HydrophobicContact CZ3-CG 4.26Å; W361-V375 WeakPolarHBondContact CA-O 3.2Å; W361-V375 VanDerWaalsContact CE3-C 3.43Å; W361-K376 HydrophobicContact CD2-CB 4.18Å; W361-K376 HydrophobicContact CD2-CG 4.25Å; W361-K376 HydrophobicContact CE3-CB 3.6Å; W361-K376 HydrophobicContact CE3-CG 4.15Å; W361-K376 HydrophobicContact CH2-CB 3.72Å; W361-K376 HydrophobicContact CH2-CD 3.89Å; W361-K376 HydrophobicContact CH2-CG 3.91Å; W361-K376 HydrophobicContact CZ2-CB 4.28Å; W361-K376 HydrophobicContact CZ2-CD 3.99Å; W361-K376 HydrophobicContact CZ2-CG 4Å; W361-K376 HydrophobicContact CZ3-CB 3.37Å; W361-K376 HydrophobicContact CZ3-CD 4.44Å; W361-K376 HydrophobicContact CZ3-CG 4.01Å; W361-Y403 CarbonylContact O-C 3.6Å; W361-Y403 WeakPolarHBondContact O-CA 3.3Å; W361-L404 HydrophobicContact CB-CB 4.2Å; W361-L404 HydrophobicContact CB-CD1 4.19Å; W361-L404 PolarHBondContact N-O 3.09Å; W361-L404 PolarHBondContact O-N 3.28Å
362V97.7Very high93.4Very high0 Ų044.5 Ų44.50%024%0.238CC..EExtended strand (participates in β ladder)trans-120.1131.5164.5175.30000109.4R364 L374 V375 V377 L395 E397 F401 R402V362-R364 HydrophobicContact CG1-CG 3.61Å; V362-L374 CarbonylContact O-C 3.6Å; V362-L374 WeakPolarHBondContact O-CA 3.33Å; V362-V375 PolarHBondContact N-O 2.04Å; V362-V375 PolarHBondContact O-N 2.81Å; V362-V377 HydrophobicContact CB-CG2 4.26Å; V362-V377 HydrophobicContact CG2-CG2 3.75Å; V362-L395 HydrophobicContact CG2-CD1 4.17Å; V362-L395 HydrophobicContact CG2-CD2 3.8Å; V362-L395 HydrophobicContact CG2-CG 4.49Å; V362-E397 HydrophobicContact CG1-CG 3.98Å; V362-F401 HydrophobicContact CG1-CB 4.14Å; V362-F401 HydrophobicContact CG1-CD2 3.84Å; V362-F401 HydrophobicContact CG1-CG 4.34Å; V362-R402 CarbonylContact C-O 3.54Å; V362-R402 WeakPolarHBondContact CA-O 3.3Å
363R96.4Very high93.4Very high59 Ų5950.1 Ų50.122%0.22326%0.259CS..EExtended strand (participates in β ladder)trans-101.5115166.9-167.7-179.8-67.6156.6-1108.6E331 V371 K373 L374 F401 R402 L404E331-R363 IonicContact OE1-CZ 3.86Å; E331-R363 IonicContact OE1-NH1 2.67Å; E331-R363 PolarHBondContact OE1-NH1 3.27Å; E331-R363 IonicContact OE1-NH2 2.87Å; E331-R363 PolarHBondContact OE1-NH2 2.94Å; E331-R363 IonicContact OE2-CZ 3.14Å; E331-R363 IonicContact OE2-NE 2.76Å; E331-R363 IonicContact OE2-NH1 2.67Å; E331-R363 PolarHBondContact OE2-NH1 3.31Å; E331-R363 IonicContact OE2-NH2 2.74Å; E331-R363 PolarHBondContact OE2-NH2 2.85Å; R363-V371 HydrophobicContact CB-CG1 4.17Å; R363-V371 VanDerWaalsContact CD-O 3.31Å; R363-V371 WeakPolarHBondContact CD-O 3.26Å; R363-V371 HydrophobicContact CG-CG1 3.9Å; R363-V371 WeakPolarHBondContact O-CG1 3.2Å; R363-K373 CarbonylContact C-O 3.59Å; R363-K373 WeakPolarHBondContact CA-O 3.36Å; R363-L374 HydrophobicContact CB-CD1 3.98Å; R363-L374 HydrophobicContact CG-CD1 4.45Å; R363-F401 CarbonylContact O-C 3.42Å; R363-F401 VanDerWaalsContact O-CA 3.31Å; R363-F401 WeakPolarHBondContact O-CA 3.4Å; R363-F401 WeakPolarHBondContact O-CB 3.29Å; R363-R402 HydrophobicContact CB-CB 4.41Å; R363-R402 PolarHBondContact N-O 2.85Å; R363-R402 PolarHBondContact O-N 2.88Å; R363-L404 HydrophobicContact CB-CD1 3.76Å
364R94.6Very high93.4Very high76 Ų7653.7 Ų53.729%0.28728%0.278SS..EExtended strand (participates in β ladder)trans-103.1160.5-172.9-54.9-177175.1161.1-0.1112.1V362 D366 V371 R372 K373 E397V362-R364 HydrophobicContact CG1-CG 3.61Å; R364-D366 PolarHBondContact O-N 2.71Å; R364-V371 CarbonylContact O-C 3.39Å; R364-V371 WeakPolarHBondContact O-CA 3.26Å; R364-R372 PolarHBondContact O-N 3.45Å; R364-K373 HydrophobicContact CB-CB 4.49Å; R364-K373 PolarHBondContact N-O 2.9Å; R364-K373 PolarHBondContact O-N 3Å; R364-K373 VanDerWaalsContact O-N 3.07Å; R364-E397 WeakPolarHBondContact CD-OE2 3.31Å; R364-E397 VanDerWaalsContact CG-OE2 3.25Å; R364-E397 WeakPolarHBondContact CG-OE2 3.09Å; R364-E397 IonicContact CZ-OE1 3.92Å; R364-E397 IonicContact CZ-OE2 3.54Å; R364-E397 IonicContact NE-OE1 3.16Å; R364-E397 PolarHBondContact NE-OE1 2.7Å; R364-E397 IonicContact NE-OE2 2.91Å; R364-E397 PolarHBondContact NE-OE2 2.85Å; R364-E397 IonicContact NH2-OE1 3.8Å; R364-E397 PolarHBondContact NH2-OE1 3.46Å
365D91Very high93.5Very high18 Ų1852.7 Ų52.710%0.09627%0.27CS..EExtended strand (participates in β ladder)trans-56.7131.7163.2-157.9-64.2000110.5S367 T368 G369 N370 Q399 K400D365-S367 PolarHBondContact O-N 2.87Å; D365-S367 WeakPolarHBondContact OD1-CA 3.41Å; D365-S367 PolarHBondContact OD1-N 3.46Å; D365-T368 PolarHBondContact OD1-N 2.62Å; D365-G369 WeakPolarHBondContact OD1-CA 3.23Å; D365-G369 PolarHBondContact OD1-N 3.43Å; D365-G369 WeakPolarHBondContact OD2-CA 3.27Å; D365-N370 CarbonylContact C-O 3.59Å; D365-N370 WeakPolarHBondContact CA-O 3.2Å; D365-N370 PolarHBondContact OD2-N 2.91Å; D365-Q399 HydrophobicContact CB-CB 4.07Å; D365-K400 PolarHBondContact N-O 3.23Å; D365-K400 WeakPolarHBondContact OD2-CE 3.42Å
366D87.4Confident93.6Very high44 Ų4455.1 Ų55.124%0.23527%0.274CS..  trans-87.218.6-18067.11.1000113.3R364 T368 N370R364-D366 PolarHBondContact O-N 2.71Å; D366-T368 PolarHBondContact O-N 3.37Å; D366-T368 WeakPolarHBondContact OD1-CA 3.37Å; D366-T368 VanDerWaalsContact OD1-CB 3.29Å; D366-T368 WeakPolarHBondContact OD1-CB 3.32Å; D366-T368 PolarHBondContact OD1-N 3.05Å; D366-T368 PolarHBondContact OD1-OG1 3.39Å; D366-T368 PolarHBondContact OD2-OG1 2.84Å; D366-N370 PolarHBondContact N-O 3.17Å
367S86.6Confident93.7Very high107 Ų10757.7 Ų57.775%0.74829%0.289SS*.SBendtrans701.7-172.671.70000115.1D365D365-S367 PolarHBondContact O-N 2.87Å; D365-S367 WeakPolarHBondContact OD1-CA 3.41Å; D365-S367 PolarHBondContact OD1-N 3.46Å
368T86.6Confident93.7Very high93 Ų9358.3 Ų58.357%0.57130%0.295SS*.SBendtrans-1002.9172.977.20000112.7D365 D366 N370D365-T368 PolarHBondContact OD1-N 2.62Å; D366-T368 PolarHBondContact O-N 3.37Å; D366-T368 WeakPolarHBondContact OD1-CA 3.37Å; D366-T368 VanDerWaalsContact OD1-CB 3.29Å; D366-T368 WeakPolarHBondContact OD1-CB 3.32Å; D366-T368 PolarHBondContact OD1-N 3.05Å; D366-T368 PolarHBondContact OD1-OG1 3.39Å; D366-T368 PolarHBondContact OD2-OG1 2.84Å; T368-N370 PolarHBondContact OG1-ND2 2.83Å
369G83.3Confident93.6Very high32 Ų3260.9 Ų60.933%0.3331%0.31SS..SBendtrans86.58.6-171.800000112.9D365 K400D365-G369 WeakPolarHBondContact OD1-CA 3.23Å; D365-G369 PolarHBondContact OD1-N 3.43Å; D365-G369 WeakPolarHBondContact OD2-CA 3.27Å; G369-K400 WeakPolarHBondContact O-CE 3.49Å; G369-K400 PolarHBondContact O-NZ 3.01Å
370N90.3Very high93.6Very high69 Ų6961.7 Ų61.737%0.36931%0.314SS..  trans-114129.1-177-67.3-61.9000111.3D365 D366 T368 R372D365-N370 CarbonylContact C-O 3.59Å; D365-N370 WeakPolarHBondContact CA-O 3.2Å; D365-N370 PolarHBondContact OD2-N 2.91Å; D366-N370 PolarHBondContact N-O 3.17Å; T368-N370 PolarHBondContact OG1-ND2 2.83Å; N370-R372 HydrophobicContact CB-CG 4.15Å; N370-R372 PolarHBondContact O-N 2.71Å; N370-R372 VanDerWaalsContact O-N 3.1Å
371V92.7Very high93.5Very high24 Ų2466.1 Ų66.115%0.14534%0.335CS..EExtended strand (participates in β ladder)trans-82.389.6-179.1-175.20000109.9I334 R363 R364 K400 R402I334-V371 HydrophobicContact CD1-CG2 4.46Å; R363-V371 HydrophobicContact CB-CG1 4.17Å; R363-V371 VanDerWaalsContact CD-O 3.31Å; R363-V371 WeakPolarHBondContact CD-O 3.26Å; R363-V371 HydrophobicContact CG-CG1 3.9Å; R363-V371 WeakPolarHBondContact O-CG1 3.2Å; R364-V371 CarbonylContact O-C 3.39Å; R364-V371 WeakPolarHBondContact O-CA 3.26Å; V371-K400 HydrophobicContact CG2-CD 4.16Å; V371-K400 HydrophobicContact CG2-CG 3.83Å; V371-R402 HydrophobicContact CG1-CG 4.31Å
372R91.3Very high93.1Very high172 Ų17264.4 Ų64.465%0.64933%0.331SS*.EExtended strand (participates in β ladder)trans-134.4-27.6-171.3-68.1-179.5178.2174.20.8115.1R364 N370 L374R364-R372 PolarHBondContact O-N 3.45Å; N370-R372 HydrophobicContact CB-CG 4.15Å; N370-R372 PolarHBondContact O-N 2.71Å; N370-R372 VanDerWaalsContact O-N 3.1Å; R372-L374 PolarHBondContact O-N 2.89Å
373K93Very high92.7Very high125 Ų12566.7 Ų66.754%0.54334%0.343SS..EExtended strand (participates in β ladder)trans-78.7109.2-172.8-177.1-179.8179.2179.80110.4R363 R364R363-K373 CarbonylContact C-O 3.59Å; R363-K373 WeakPolarHBondContact CA-O 3.36Å; R364-K373 HydrophobicContact CB-CB 4.49Å; R364-K373 PolarHBondContact N-O 2.9Å; R364-K373 PolarHBondContact O-N 3Å; R364-K373 VanDerWaalsContact O-N 3.07Å
374L94.1Very high92.3Very high82 Ų8269.1 Ų69.143%0.42936%0.361SS..EExtended strand (participates in β ladder)trans-85.5135.8179.8-160.871000111.5W361 V362 R363 R372 L404W361-L374 HydrophobicContact CB-CD1 3.94Å; W361-L374 HydrophobicContact CB-CG 4.37Å; W361-L374 HydrophobicContact CD2-CD2 4.1Å; W361-L374 HydrophobicContact CD2-CG 4.23Å; W361-L374 HydrophobicContact CE3-CD1 4.45Å; W361-L374 HydrophobicContact CE3-CD2 3.7Å; W361-L374 HydrophobicContact CE3-CG 3.64Å; W361-L374 HydrophobicContact CG-CD1 4.49Å; W361-L374 HydrophobicContact CZ3-CD2 4.04Å; W361-L374 HydrophobicContact CZ3-CG 4.26Å; V362-L374 CarbonylContact O-C 3.6Å; V362-L374 WeakPolarHBondContact O-CA 3.33Å; R363-L374 HydrophobicContact CB-CD1 3.98Å; R363-L374 HydrophobicContact CG-CD1 4.45Å; R372-L374 PolarHBondContact O-N 2.89Å; L374-L404 HydrophobicContact CD1-CD1 3.97Å; L374-L404 HydrophobicContact CD1-CD2 3.97Å
375V96Very high91.9Very high37 Ų3767.6 Ų67.622%0.22436%0.358CS..EExtended strand (participates in β ladder)trans-134.9125.7179.2-178.50000109W361 V362W361-V375 WeakPolarHBondContact CA-O 3.2Å; W361-V375 VanDerWaalsContact CE3-C 3.43Å; V362-V375 PolarHBondContact N-O 2.04Å; V362-V375 PolarHBondContact O-N 2.81Å
376K97.2Very high91.8Very high109 Ų10970.2 Ų70.247%0.47437%0.37SS..EExtended strand (participates in β ladder)trans-73.9130175.2-164.6172.1171.41750108.8I359 W361 T379I359-K376 HydrophobicContact CG2-CD 4.1Å; I359-K376 VanDerWaalsContact CG2-CE 3.5Å; I359-K376 HydrophobicContact CG2-CG 3.79Å; W361-K376 HydrophobicContact CD2-CB 4.18Å; W361-K376 HydrophobicContact CD2-CG 4.25Å; W361-K376 HydrophobicContact CE3-CB 3.6Å; W361-K376 HydrophobicContact CE3-CG 4.15Å; W361-K376 HydrophobicContact CH2-CB 3.72Å; W361-K376 HydrophobicContact CH2-CD 3.89Å; W361-K376 HydrophobicContact CH2-CG 3.91Å; W361-K376 HydrophobicContact CZ2-CB 4.28Å; W361-K376 HydrophobicContact CZ2-CD 3.99Å; W361-K376 HydrophobicContact CZ2-CG 4Å; W361-K376 HydrophobicContact CZ3-CB 3.37Å; W361-K376 HydrophobicContact CZ3-CD 4.44Å; W361-K376 HydrophobicContact CZ3-CG 4.01Å; K376-T379 WeakPolarHBondContact CE-OG1 3.23Å; K376-T379 PolarHBondContact NZ-OG1 3.21Å; K376-T379 VanDerWaalsContact NZ-OG1 3.12Å
377V97.6Very high91.9Very high53 Ų5370.8 Ų70.832%0.32137%0.373SS..EExtended strand (participates in β ladder)trans-107.2-57.9-178.4-1760000111.1V360 V362 V393 L395V360-V377 HydrophobicContact CG1-CB 4.49Å; V360-V377 WeakPolarHBondContact O-CB 3.26Å; V360-V377 PolarHBondContact O-N 2.85Å; V362-V377 HydrophobicContact CB-CG2 4.26Å; V362-V377 HydrophobicContact CG2-CG2 3.75Å; V377-V393 HydrophobicContact CB-CG1 4.35Å; V377-V393 HydrophobicContact CG1-CG1 3.45Å; V377-V393 VanDerWaalsContact CG1-CG1 3.45Å; V377-L395 HydrophobicContact CG1-CD2 4.04Å; V377-L395 HydrophobicContact CG2-CD2 4.3Å
378Q97.7Very high92.3Very high71 Ų7166.2 Ų66.233%0.33234%0.339SS..EExtended strand (participates in β ladder)trans-146.2153.6-174.1-168.5157.7-600111.5I359 V360 F380 V393I359-Q378 CarbonylContact C-O 3.41Å; I359-Q378 WeakPolarHBondContact CA-O 3.41Å; I359-Q378 WeakPolarHBondContact CG2-O 3.35Å; V360-Q378 PolarHBondContact N-O 3.04Å; V360-Q378 PolarHBondContact O-N 2.91Å; Q378-F380 HydrophobicContact CB-CE2 4.24Å; Q378-F380 HydrophobicContact CG-CE1 4.45Å; Q378-F380 HydrophobicContact CG-CE2 3.85Å; Q378-F380 HydrophobicContact CG-CZ 3.82Å; Q378-V393 HydrophobicContact CB-CG1 4.18Å; Q378-V393 HydrophobicContact CB-CG2 4.46Å
379T98Very high92.7Very high53 Ų5363.4 Ų63.433%0.32532%0.319SS..EExtended strand (participates in β ladder)trans-130.6128.8174.9-60.30000109.1R357 L358 I359 K376R357-T379 HydrophobicContact CB-CG2 4.36Å; L358-T379 CarbonylContact O-C 3.42Å; L358-T379 WeakPolarHBondContact O-CA 3.47Å; I359-T379 HydrophobicContact CG1-CG2 3.89Å; K376-T379 WeakPolarHBondContact CE-OG1 3.23Å; K376-T379 PolarHBondContact NZ-OG1 3.21Å; K376-T379 VanDerWaalsContact NZ-OG1 3.12Å
380F97.4Very high93.4Very high24 Ų2462.9 Ų62.911%0.10531%0.309CS..EExtended strand (participates in β ladder)trans-106.2134172.5-56.1-90.7000107.8F346 Y348 M350 R357 L358 V360 Q378 A391 V393F346-F380 HydrophobicContact CZ-CD2 4.45Å; F346-F380 AromaticContact CZ-CE2 3.79Å; F346-F380 HydrophobicContact CZ-CE2 3.79Å; F346-F380 HydrophobicContact CZ-CZ 4.14Å; Y348-F380 HydrophobicContact CE1-CD1 4.19Å; Y348-F380 HydrophobicContact CE2-CB 4.27Å; Y348-F380 AromaticContact CZ-CD1 3.95Å; M350-F380 HydrophobicContact CE-CB 4.27Å; R357-F380 WeakPolarHBondContact CA-O 3.49Å; L358-F380 HydrophobicContact CB-CB 4.3Å; L358-F380 HydrophobicContact CD2-CD2 4.39Å; L358-F380 HydrophobicContact CG-CD2 4.45Å; L358-F380 PolarHBondContact N-O 3.49Å; L358-F380 PolarHBondContact O-N 3.17Å; V360-F380 HydrophobicContact CG2-CE2 4.03Å; Q378-F380 HydrophobicContact CB-CE2 4.24Å; Q378-F380 HydrophobicContact CG-CE1 4.45Å; Q378-F380 HydrophobicContact CG-CE2 3.85Å; Q378-F380 HydrophobicContact CG-CZ 3.82Å; F380-A391 HydrophobicContact CE1-CB 3.79Å; F380-A391 HydrophobicContact CE2-CB 4.46Å; F380-A391 HydrophobicContact CZ-CB 3.67Å; F380-V393 HydrophobicContact CE2-CG2 4.1Å; F380-V393 HydrophobicContact CZ-CG2 3.85Å
381Q95.6Very high93.7Very high94 Ų9459.8 Ų59.844%0.43929%0.293SS..EExtended strand (participates in β ladder)trans-102.7146.3-178.6-166.667.449.600109P354 S355 D356P354-Q381 WeakPolarHBondContact O-CG 3.37Å; P354-Q381 PolarHBondContact O-NE2 3.48Å; S355-Q381 VanDerWaalsContact C-NE2 3.25Å; S355-Q381 PolarHBondContact O-NE2 3.47Å; D356-Q381 PolarHBondContact O-NE2 2.96Å; D356-Q381 VanDerWaalsContact O-NE2 3.16Å
382G91.2Very high93.9Very high10 Ų1060.1 Ų60.110%0.10329%0.292CS..  trans-58.9149.8171.500000112.7M350 D356M350-G382 WeakPolarHBondContact SD-CA 3.24Å; D356-G382 PolarHBondContact O-N 3.3Å
383D89.1Confident94.3Very high48 Ų4851.9 Ų51.926%0.25726%0.261SS..  trans-143.2174.2176.561.449.7000110.8D385 H386 K389D383-D385 WeakPolarHBondContact OD1-CB 3.17Å; D383-D385 PolarHBondContact OD1-N 3.43Å; D383-D385 VanDerWaalsContact OD1-N 3.08Å; D383-H386 PolarHBondContact O-ND1 2.99Å; D383-K389 IonicContact OD1-NZ 2.97Å; D383-K389 PolarHBondContact OD1-NZ 2.79Å; D383-K389 WeakPolarHBondContact OD2-CE 3.31Å; D383-K389 IonicContact OD2-NZ 3.38Å; D383-K389 PolarHBondContact OD2-NZ 3.13Å
384D88.2Confident94.5Very high110 Ų11049.1 Ų49.159%0.58825%0.254SS*.SBendtrans-89.1-2.8-176.8-57.6-37000113.4P354 H386P354-D384 WeakPolarHBondContact CG-OD1 3.46Å; D384-H386 VanDerWaalsContact C-N 3.31Å; D384-H386 PolarHBondContact O-CD2 2.92Å
385D84.8Confident94.7Very high44 Ų4445.3 Ų45.324%0.23524%0.235CC..  trans-73-27.8-176.2-179.926.4000110.9D383 N387 K389 Q439D383-D385 WeakPolarHBondContact OD1-CB 3.17Å; D383-D385 PolarHBondContact OD1-N 3.43Å; D383-D385 VanDerWaalsContact OD1-N 3.08Å; D385-N387 PolarHBondContact O-N 2.98Å; D385-N387 PolarHBondContact O-ND2 3.27Å; D385-N387 PolarHBondContact OD1-ND2 2.95Å; D385-K389 WeakPolarHBondContact OD2-CE 3.31Å; D385-K389 IonicContact OD2-NZ 2.86Å; D385-Q439 PolarHBondContact OD1-NE2 3.05Å; D385-Q439 PolarHBondContact OD2-NE2 2.63Å
386H89.1Confident94.7Very high74 Ų7450.5 Ų50.534%0.34325%0.254SS..  trans536.2174.8-60-34.3000116K349 M350 T351 D383 D384K349-H386 WeakPolarHBondContact CE-O 3.13Å; K349-H386 VanDerWaalsContact CG-O 3.25Å; K349-H386 WeakPolarHBondContact CG-O 3.19Å; M350-H386 PolarHBondContact O-ND1 2.82Å; T351-H386 HydrophobicContact CG2-CB 4.21Å; D383-H386 PolarHBondContact O-ND1 2.99Å; D384-H386 VanDerWaalsContact C-N 3.31Å; D384-H386 PolarHBondContact O-CD2 2.92Å
387N91.3Very high94.6Very high55 Ų5545.8 Ų45.829%0.29423%0.234SC..SBendtrans-87.8161.1179.6-72.9-43.8000111.7D385D385-N387 PolarHBondContact O-N 2.98Å; D385-N387 PolarHBondContact O-ND2 3.27Å; D385-N387 PolarHBondContact OD1-ND2 2.95Å
388W93.8Very high94.4Very high11 Ų1149.6 Ų49.64%0.04225%0.248CC..  trans-63.5134.5168.8-78.7111.6000109.7V300 H302 F347 Y348 K349 D422V300-W388 WeakPolarHBondContact O-CZ2 3.38Å; V300-W388 PolarHBondContact O-NE1 2.88Å; H302-W388 HydrophobicContact CB-CD2 3.94Å; H302-W388 HydrophobicContact CB-CE3 4.19Å; H302-W388 HydrophobicContact CB-CG 4.4Å; H302-W388 HydrophobicContact CB-CH2 4.38Å; H302-W388 HydrophobicContact CB-CZ2 4.15Å; H302-W388 HydrophobicContact CB-CZ3 4.39Å; H302-W388 AromaticContact CD2-CG 3.86Å; F347-W388 HydrophobicContact CB-CE3 3.9Å; F347-W388 HydrophobicContact CB-CZ3 4.21Å; Y348-W388 VanDerWaalsContact C-CE3 3.43Å; K349-W388 HydrophobicContact CB-CD2 3.81Å; K349-W388 HydrophobicContact CB-CE3 3.76Å; K349-W388 HydrophobicContact CB-CG 4.32Å; K349-W388 HydrophobicContact CB-CH2 4.49Å; K349-W388 HydrophobicContact CB-CZ3 4.12Å; K349-W388 HydrophobicContact CD-CD2 4.37Å; K349-W388 HydrophobicContact CD-CG 4.48Å; W388-D422 HydrophobicContact CH2-CB 3.72Å; W388-D422 HydrophobicContact CZ2-CB 4.49Å; W388-D422 HydrophobicContact CZ3-CB 4.01Å
389K95Very high94.2Very high35 Ų3551.4 Ų51.415%0.15226%0.257CS..EExtended strand (participates in β ladder)trans-128143.9179.6-58.5-169.6-177.786.40109.3F347 Y348 D383 D385F347-K389 CarbonylContact C-O 3.57Å; F347-K389 VanDerWaalsContact CA-O 3.28Å; F347-K389 WeakPolarHBondContact CA-O 3.48Å; Y348-K389 HydrophobicContact CD1-CB 4.1Å; Y348-K389 WeakPolarHBondContact CD1-O 3.45Å; Y348-K389 HydrophobicContact CE1-CB 3.61Å; Y348-K389 HydrophobicContact CE2-CB 4.49Å; Y348-K389 PolarHBondContact N-O 3.32Å; Y348-K389 PolarHBondContact O-N 3.41Å; D383-K389 IonicContact OD1-NZ 2.97Å; D383-K389 PolarHBondContact OD1-NZ 2.79Å; D383-K389 WeakPolarHBondContact OD2-CE 3.31Å; D383-K389 IonicContact OD2-NZ 3.38Å; D383-K389 PolarHBondContact OD2-NZ 3.13Å; D385-K389 WeakPolarHBondContact OD2-CE 3.31Å; D385-K389 IonicContact OD2-NZ 2.86Å
390I97.2Very high94Very high21 Ų2151.9 Ų51.911%0.10825%0.254CS..EExtended strand (participates in β ladder)trans-91.9130.9172.4-170.2169.2000109.8Q345 F347 V435 L511 I588 F590Q345-I390 HydrophobicContact CG-CD1 3.89Å; Q345-I390 HydrophobicContact CG-CG1 3.94Å; F347-I390 HydrophobicContact CD1-CB 4.16Å; F347-I390 HydrophobicContact CE1-CB 3.82Å; F347-I390 HydrophobicContact CE1-CD1 4.44Å; F347-I390 HydrophobicContact CE1-CG1 4.35Å; F347-I390 HydrophobicContact CE2-CD1 4.01Å; F347-I390 HydrophobicContact CE2-CG1 4.24Å; F347-I390 HydrophobicContact CZ-CB 4.05Å; F347-I390 HydrophobicContact CZ-CD1 3.8Å; F347-I390 HydrophobicContact CZ-CG1 4.11Å; I390-V435 HydrophobicContact CG2-CG1 3.91Å; I390-L511 HydrophobicContact CD1-CD2 3.9Å; I390-I588 HydrophobicContact CB-CD1 4.32Å; I390-I588 HydrophobicContact CG2-CD1 4.02Å; I390-I588 HydrophobicContact CG2-CG2 4.21Å; I390-F590 HydrophobicContact CD1-CE1 4.28Å; I390-F590 HydrophobicContact CD1-CZ 3.88Å
391A97.5Very high94Very high4 Ų450.8 Ų50.83%0.03325%0.249CC..EExtended strand (participates in β ladder)trans-112146.7173.200000110.4Q345 F346 Y348 F380Q345-A391 VanDerWaalsContact CA-O 3.27Å; Q345-A391 WeakPolarHBondContact CA-O 3.4Å; F346-A391 HydrophobicContact CD1-CB 4.28Å; F346-A391 HydrophobicContact CD2-CB 4.15Å; F346-A391 HydrophobicContact CE1-CB 3.79Å; F346-A391 HydrophobicContact CE2-CB 3.63Å; F346-A391 HydrophobicContact CG-CB 4.45Å; F346-A391 HydrophobicContact CZ-CB 3.44Å; F346-A391 VanDerWaalsContact CZ-CB 3.44Å; F346-A391 PolarHBondContact N-O 2.93Å; F346-A391 VanDerWaalsContact N-O 3.16Å; F346-A391 PolarHBondContact O-N 3.42Å; Y348-A391 HydrophobicContact CD1-CB 3.91Å; Y348-A391 HydrophobicContact CE1-CB 3.85Å; F380-A391 HydrophobicContact CE1-CB 3.79Å; F380-A391 HydrophobicContact CE2-CB 4.46Å; F380-A391 HydrophobicContact CZ-CB 3.67Å
392H98Very high94.1Very high30 Ų3048.5 Ų48.514%0.13924%0.237CC..EExtended strand (participates in β ladder)trans-128.8125.2170.5-63.786.1000108.8L344 Q345 C431 P432 F590L344-H392 CarbonylContact O-C 3.54Å; L344-H392 WeakPolarHBondContact O-CA 3.25Å; Q345-H392 PolarHBondContact OE1-NE2 2.8Å; H392-C431 HydrophobicContact CB-CB 4.09Å; H392-P432 VanDerWaalsContact CD2-CD 3.49Å; H392-P432 WeakPolarHBondContact CD2-CD 3.45Å; H392-F590 AromaticContact CE1-CE1 3.55Å; H392-F590 AromaticContact CE1-CZ 3.48Å; H392-F590 VanDerWaalsContact CE1-CZ 3.48Å; H392-F590 WeakPolarHBondContact CE1-CZ 3.47Å; H392-F590 AromaticContact NE2-CZ 3.5Å
393V98.2Very high94.5Very high0 Ų048 Ų480%023%0.232CC..EExtended strand (participates in β ladder)trans-126.1118.3-177.1-174.50000109.2L344 F346 V360 V377 Q378 F380 L395L344-V393 HydrophobicContact CB-CB 4.27Å; L344-V393 PolarHBondContact N-O 2.87Å; L344-V393 PolarHBondContact O-N 2.8Å; F346-V393 HydrophobicContact CE1-CG2 3.88Å; F346-V393 HydrophobicContact CZ-CG2 4.38Å; V360-V393 HydrophobicContact CG1-CG1 4.2Å; V360-V393 HydrophobicContact CG2-CG2 4.27Å; V377-V393 HydrophobicContact CB-CG1 4.35Å; V377-V393 HydrophobicContact CG1-CG1 3.45Å; V377-V393 VanDerWaalsContact CG1-CG1 3.45Å; Q378-V393 HydrophobicContact CB-CG1 4.18Å; Q378-V393 HydrophobicContact CB-CG2 4.46Å; F380-V393 HydrophobicContact CE2-CG2 4.1Å; F380-V393 HydrophobicContact CZ-CG2 3.85Å; V393-L395 HydrophobicContact CG1-CD2 3.91Å; V393-L395 PolarHBondContact O-N 3.18Å
394V97.6Very high94.9Very high66 Ų6645.8 Ų45.840%0.422%0.22SC..EExtended strand (participates in β ladder)trans-76.5121.9178.5179.60000109.9Q341 K396 C431Q341-V394 HydrophobicContact CG-CG1 4.23Å; V394-K396 HydrophobicContact CG1-CG 4.43Å; V394-C431 HydrophobicContact CG2-CB 3.78Å
395L97.6Very high95.4Very high3 Ų340.6 Ų40.62%0.01619%0.192CC..EExtended strand (participates in β ladder)trans-110.6150.4171.5-43.2-178000109.6Q341 Q342 L344 V362 V377 V393 E397 F401 L426Q341-L395 WeakPolarHBondContact CA-O 3.29Å; Q342-L395 HydrophobicContact CB-CB 4.22Å; Q342-L395 PolarHBondContact N-O 3.37Å; Q342-L395 PolarHBondContact O-N 2.77Å; Q342-L395 PolarHBondContact OE1-O 2.88Å; L344-L395 HydrophobicContact CB-CD1 4.15Å; L344-L395 HydrophobicContact CB-CG 4.36Å; V362-L395 HydrophobicContact CG2-CD1 4.17Å; V362-L395 HydrophobicContact CG2-CD2 3.8Å; V362-L395 HydrophobicContact CG2-CG 4.49Å; V377-L395 HydrophobicContact CG1-CD2 4.04Å; V377-L395 HydrophobicContact CG2-CD2 4.3Å; V393-L395 HydrophobicContact CG1-CD2 3.91Å; V393-L395 PolarHBondContact O-N 3.18Å; L395-E397 HydrophobicContact CB-CG 4.36Å; L395-F401 HydrophobicContact CD1-CE2 3.88Å; L395-F401 HydrophobicContact CD1-CZ 4.32Å; L395-L426 HydrophobicContact CD1-CD1 3.92Å
396K96.3Very high96Very high146 Ų14640.2 Ų40.264%0.63519%0.189SC*.  trans-133.161.7-178.9-65.9-174.4179.7-177.70110.1K340 V394K340-K396 VanDerWaalsContact O-CA 3.31Å; K340-K396 WeakPolarHBondContact O-CA 3.43Å; V394-K396 HydrophobicContact CG1-CG 4.43Å
397E95Very high96.4Very high10 Ų1036.7 Ų36.75%0.04717%0.173CC..  trans-102.8126.3-174.9-53-52.1146.500110.6P337 Q342 V362 R364 L395 F401P337-E397 WeakPolarHBondContact CB-O 3.4Å; P337-E397 HydrophobicContact CG-CB 4.44Å; P337-E397 VanDerWaalsContact CG-O 3.32Å; P337-E397 WeakPolarHBondContact CG-O 3.37Å; Q342-E397 PolarHBondContact NE2-O 2.7Å; V362-E397 HydrophobicContact CG1-CG 3.98Å; R364-E397 WeakPolarHBondContact CD-OE2 3.31Å; R364-E397 VanDerWaalsContact CG-OE2 3.25Å; R364-E397 WeakPolarHBondContact CG-OE2 3.09Å; R364-E397 IonicContact CZ-OE1 3.92Å; R364-E397 IonicContact CZ-OE2 3.54Å; R364-E397 IonicContact NE-OE1 3.16Å; R364-E397 PolarHBondContact NE-OE1 2.7Å; R364-E397 IonicContact NE-OE2 2.91Å; R364-E397 PolarHBondContact NE-OE2 2.85Å; R364-E397 IonicContact NH2-OE1 3.8Å; R364-E397 PolarHBondContact NH2-OE1 3.46Å; L395-E397 HydrophobicContact CB-CG 4.36Å; E397-F401 HydrophobicContact CB-CB 4.48Å; E397-F401 HydrophobicContact CB-CD1 3.51Å; E397-F401 HydrophobicContact CB-CD2 4.43Å; E397-F401 HydrophobicContact CB-CE1 3.67Å; E397-F401 HydrophobicContact CB-CG 3.91Å; E397-F401 HydrophobicContact CB-CZ 4.18Å; E397-F401 HydrophobicContact CG-CB 4.38Å; E397-F401 HydrophobicContact CG-CD1 3.93Å; E397-F401 HydrophobicContact CG-CD2 3.91Å; E397-F401 HydrophobicContact CG-CE1 4.09Å; E397-F401 HydrophobicContact CG-CE2 4.07Å; E397-F401 HydrophobicContact CG-CG 3.82Å; E397-F401 HydrophobicContact CG-CZ 4.14Å
398E93.6Very high96.7Very high132 Ų13234.2 Ų34.262%0.61716%0.159SC*.  trans-106.8-9.9178.3-60.1-169.9174.800112.8K340K340-E398 HydrophobicContact CB-CG 4.33Å; K340-E398 WeakPolarHBondContact CD-OE1 3.47Å; K340-E398 HydrophobicContact CG-CG 4.14Å
399Q93.2Very high96.9Very high110 Ų11034 Ų3451%0.51416%0.159SC..SBendtrans-122.7168.5179.4-66-176.454.800109.6P337 D365 F401P337-Q399 WeakPolarHBondContact CD-O 3.31Å; P337-Q399 VanDerWaalsContact CG-O 3.29Å; P337-Q399 WeakPolarHBondContact CG-O 3.31Å; D365-Q399 HydrophobicContact CB-CB 4.07Å; Q399-F401 WeakPolarHBondContact O-CD1 3.5Å; Q399-F401 PolarHBondContact O-N 2.82Å
400K95.1Very high96.9Very high63 Ų6332.9 Ų32.927%0.27416%0.157SC..  trans-56137.3177.767.8-178.5180-177.20111.6I334 L335 Y336 D365 G369 V371I334-K400 HydrophobicContact CG2-CB 3.85Å; I334-K400 HydrophobicContact CG2-CD 4.19Å; I334-K400 HydrophobicContact CG2-CG 4.3Å; L335-K400 CarbonylContact O-C 3.52Å; L335-K400 WeakPolarHBondContact O-CA 3.33Å; L335-K400 WeakPolarHBondContact O-CB 3.27Å; Y336-K400 HydrophobicContact CD1-CB 3.85Å; Y336-K400 HydrophobicContact CE1-CB 3.9Å; Y336-K400 HydrophobicContact CE1-CD 4.05Å; D365-K400 PolarHBondContact N-O 3.23Å; D365-K400 WeakPolarHBondContact OD2-CE 3.42Å; G369-K400 WeakPolarHBondContact O-CE 3.49Å; G369-K400 PolarHBondContact O-NZ 3.01Å; V371-K400 HydrophobicContact CG2-CD 4.16Å; V371-K400 HydrophobicContact CG2-CG 3.83Å
401F97.5Very high96.8Very high0 Ų034.3 Ų34.30%017%0.165CC..EExtended strand (participates in β ladder)trans-150.4174.1-173.673.6-81.1000111.9L266 L335 P337 V362 R363 L395 E397 Q399 L426L266-F401 HydrophobicContact CD1-CE1 4.48Å; L335-F401 HydrophobicContact CB-CE1 4.3Å; L335-F401 HydrophobicContact CD1-CE2 4.49Å; L335-F401 HydrophobicContact CD1-CZ 4.5Å; L335-F401 PolarHBondContact N-O 2.81Å; L335-F401 PolarHBondContact O-N 3.2Å; L335-F401 VanDerWaalsContact O-N 3.08Å; P337-F401 HydrophobicContact CB-CE1 4.18Å; P337-F401 HydrophobicContact CG-CD1 3.99Å; P337-F401 HydrophobicContact CG-CE1 3.91Å; V362-F401 HydrophobicContact CG1-CB 4.14Å; V362-F401 HydrophobicContact CG1-CD2 3.84Å; V362-F401 HydrophobicContact CG1-CG 4.34Å; R363-F401 CarbonylContact O-C 3.42Å; R363-F401 VanDerWaalsContact O-CA 3.31Å; R363-F401 WeakPolarHBondContact O-CA 3.4Å; R363-F401 WeakPolarHBondContact O-CB 3.29Å; L395-F401 HydrophobicContact CD1-CE2 3.88Å; L395-F401 HydrophobicContact CD1-CZ 4.32Å; E397-F401 HydrophobicContact CB-CB 4.48Å; E397-F401 HydrophobicContact CB-CD1 3.51Å; E397-F401 HydrophobicContact CB-CD2 4.43Å; E397-F401 HydrophobicContact CB-CE1 3.67Å; E397-F401 HydrophobicContact CB-CG 3.91Å; E397-F401 HydrophobicContact CB-CZ 4.18Å; E397-F401 HydrophobicContact CG-CB 4.38Å; E397-F401 HydrophobicContact CG-CD1 3.93Å; E397-F401 HydrophobicContact CG-CD2 3.91Å; E397-F401 HydrophobicContact CG-CE1 4.09Å; E397-F401 HydrophobicContact CG-CE2 4.07Å; E397-F401 HydrophobicContact CG-CG 3.82Å; E397-F401 HydrophobicContact CG-CZ 4.14Å; Q399-F401 WeakPolarHBondContact O-CD1 3.5Å; Q399-F401 PolarHBondContact O-N 2.82Å; F401-L426 HydrophobicContact CE2-CD2 4.4Å; F401-L426 HydrophobicContact CZ-CD2 3.9Å
402R97.9Very high96.5Very high46 Ų4634.7 Ų34.717%0.17417%0.167CC..EExtended strand (participates in β ladder)trans-125.1139163.1-63.4-179.3179.5-114.56.4108.7S332 I334 V362 R363 V371 L404S332-R402 WeakPolarHBondContact O-CD 3.33Å; S332-R402 WeakPolarHBondContact O-CG 3.22Å; S332-R402 PolarHBondContact O-NH1 2.91Å; S332-R402 WeakPolarHBondContact OG-CA 3.44Å; I334-R402 HydrophobicContact CG1-CG 4.34Å; V362-R402 CarbonylContact C-O 3.54Å; V362-R402 WeakPolarHBondContact CA-O 3.3Å; R363-R402 HydrophobicContact CB-CB 4.41Å; R363-R402 PolarHBondContact N-O 2.85Å; R363-R402 PolarHBondContact O-N 2.88Å; V371-R402 HydrophobicContact CG1-CG 4.31Å; R402-L404 HydrophobicContact CB-CD1 4.33Å; R402-L404 WeakPolarHBondContact O-CD1 3.14Å
403Y98.1Very high96.2Very high0 Ų041.2 Ų41.20%020%0.198CC..EExtended strand (participates in β ladder)trans-89.6151.3156.868.4-98.1000109.9D267 M279 S332 L335 L344 W361 F405 I424 L426D267-Y403 HydrophobicContact CB-CE1 4.39Å; D267-Y403 PolarHBondContact OD2-OH 3.18Å; M279-Y403 HydrophobicContact CE-CE2 3.78Å; S332-Y403 VanDerWaalsContact CB-CE1 3.46Å; S332-Y403 PolarHBondContact N-O 2.8Å; S332-Y403 WeakPolarHBondContact OG-CD1 3.39Å; S332-Y403 PolarHBondContact OG-N 3.24Å; S332-Y403 PolarHBondContact OG-O 3.24Å; L335-Y403 HydrophobicContact CD1-CD1 3.66Å; L335-Y403 HydrophobicContact CD1-CE1 3.63Å; L344-Y403 HydrophobicContact CD1-CD1 4.28Å; L344-Y403 HydrophobicContact CD1-CD2 4.23Å; L344-Y403 HydrophobicContact CD1-CE1 4.18Å; L344-Y403 HydrophobicContact CD1-CE2 4.16Å; L344-Y403 HydrophobicContact CD1-CG 4.29Å; L344-Y403 HydrophobicContact CD2-CD2 4.04Å; L344-Y403 HydrophobicContact CD2-CG 4.1Å; W361-Y403 CarbonylContact O-C 3.6Å; W361-Y403 WeakPolarHBondContact O-CA 3.3Å; Y403-F405 HydrophobicContact CD2-CD2 4.44Å; Y403-F405 AromaticContact CD2-CE2 3.9Å; Y403-F405 HydrophobicContact CD2-CE2 3.9Å; Y403-F405 HydrophobicContact CD2-CZ 4.28Å; Y403-F405 HydrophobicContact CE2-CD2 4.32Å; Y403-F405 AromaticContact CE2-CE2 3.56Å; Y403-F405 HydrophobicContact CE2-CE2 3.56Å; Y403-F405 HydrophobicContact CE2-CZ 4.14Å; Y403-I424 HydrophobicContact CE2-CG2 4.17Å; Y403-I424 WeakPolarHBondContact OH-CG2 3.36Å; Y403-L426 HydrophobicContact CD1-CD2 4.03Å; Y403-L426 HydrophobicContact CE1-CB 4.4Å; Y403-L426 HydrophobicContact CE1-CD2 4.08Å
404L97.6Very high95.8Very high2 Ų247 Ų471%0.0123%0.229CC..EExtended strand (participates in β ladder)trans-137144.9-177.3-50.777.8000110.3L330 E331 V360 W361 R363 L374 R402L330-L404 CarbonylContact O-C 3.54Å; L330-L404 VanDerWaalsContact O-CA 3.31Å; L330-L404 WeakPolarHBondContact O-CA 3.32Å; E331-L404 HydrophobicContact CB-CD2 4.36Å; E331-L404 HydrophobicContact CB-CG 3.99Å; E331-L404 HydrophobicContact CG-CB 4.26Å; E331-L404 HydrophobicContact CG-CD2 3.51Å; E331-L404 HydrophobicContact CG-CG 3.66Å; E331-L404 WeakPolarHBondContact OE2-CD2 3.33Å; V360-L404 WeakPolarHBondContact CA-O 3.12Å; W361-L404 HydrophobicContact CB-CB 4.2Å; W361-L404 HydrophobicContact CB-CD1 4.19Å; W361-L404 PolarHBondContact N-O 3.09Å; W361-L404 PolarHBondContact O-N 3.28Å; R363-L404 HydrophobicContact CB-CD1 3.76Å; L374-L404 HydrophobicContact CD1-CD1 3.97Å; L374-L404 HydrophobicContact CD1-CD2 3.97Å; R402-L404 HydrophobicContact CB-CD1 4.33Å; R402-L404 WeakPolarHBondContact O-CD1 3.14Å
405F98.6Very high95.5Very high0 Ų044.3 Ų44.30%021%0.213CC..EExtended strand (participates in β ladder)trans-106.6120.4167.1-61.7-74.4000109.3M279 W289 L329 L330 L344 F346 L358 V360 Y403 L421 I424M279-F405 HydrophobicContact CE-CD2 4.29Å; M279-F405 HydrophobicContact CE-CE2 4.32Å; W289-F405 HydrophobicContact CZ2-CB 4.38Å; L329-F405 WeakPolarHBondContact CA-O 3.49Å; L330-F405 PolarHBondContact N-O 3.37Å; L330-F405 PolarHBondContact O-N 2.84Å; L344-F405 HydrophobicContact CD2-CE1 4.46Å; L344-F405 HydrophobicContact CD2-CZ 4.24Å; F346-F405 HydrophobicContact CB-CZ 4.41Å; F346-F405 AromaticContact CD1-CE1 3.75Å; F346-F405 HydrophobicContact CD1-CE1 3.75Å; F346-F405 AromaticContact CD1-CZ 3.84Å; F346-F405 HydrophobicContact CD1-CZ 3.84Å; F346-F405 AromaticContact CD2-CE1 4Å; F346-F405 HydrophobicContact CD2-CE1 4Å; F346-F405 HydrophobicContact CD2-CZ 4.36Å; F346-F405 AromaticContact CE1-CE1 3.63Å; F346-F405 HydrophobicContact CE1-CE1 3.63Å; F346-F405 HydrophobicContact CE1-CZ 4.17Å; F346-F405 AromaticContact CE2-CE1 3.89Å; F346-F405 HydrophobicContact CE2-CE1 3.89Å; F346-F405 AromaticContact CG-CE1 3.94Å; F346-F405 HydrophobicContact CG-CE1 3.94Å; F346-F405 AromaticContact CG-CZ 3.94Å; F346-F405 HydrophobicContact CG-CZ 3.94Å; F346-F405 AromaticContact CZ-CE1 3.7Å; F346-F405 HydrophobicContact CZ-CE1 3.7Å; L358-F405 HydrophobicContact CD1-CB 4.06Å; L358-F405 HydrophobicContact CD1-CD1 4.09Å; V360-F405 HydrophobicContact CG2-CD1 3.97Å; V360-F405 HydrophobicContact CG2-CE1 3.92Å; Y403-F405 HydrophobicContact CD2-CD2 4.44Å; Y403-F405 AromaticContact CD2-CE2 3.9Å; Y403-F405 HydrophobicContact CD2-CE2 3.9Å; Y403-F405 HydrophobicContact CD2-CZ 4.28Å; Y403-F405 HydrophobicContact CE2-CD2 4.32Å; Y403-F405 AromaticContact CE2-CE2 3.56Å; Y403-F405 HydrophobicContact CE2-CE2 3.56Å; Y403-F405 HydrophobicContact CE2-CZ 4.14Å; F405-L421 HydrophobicContact CB-CD1 3.65Å; F405-L421 HydrophobicContact CD1-CD1 4.04Å; F405-L421 HydrophobicContact CD1-CD2 4.22Å; F405-L421 HydrophobicContact CD2-CD1 3.8Å; F405-L421 HydrophobicContact CE1-CD2 4.34Å; F405-L421 HydrophobicContact CE2-CD1 4.41Å; F405-L421 HydrophobicContact CG-CD1 3.56Å; F405-I424 HydrophobicContact CD2-CD1 4.49Å; F405-I424 HydrophobicContact CE2-CD1 3.62Å; F405-I424 HydrophobicContact CE2-CG1 4.16Å; F405-I424 HydrophobicContact CZ-CD1 4.22Å; F405-I424 HydrophobicContact CZ-CG1 4.26Å; F405-I424 HydrophobicContact CZ-CG2 4.49Å
406Q98.1Very high95.1Very high37 Ų3750.5 Ų50.517%0.17325%0.251CS..EExtended strand (participates in β ladder)trans-104.3113.1168.1175.6-175.6-15.700108.5A327 A328 L329 L358 I359 T408A327-Q406 HydrophobicContact CB-CG 4.12Å; A328-Q406 CarbonylContact O-C 3.51Å; A328-Q406 VanDerWaalsContact O-CA 3.3Å; A328-Q406 WeakPolarHBondContact O-CA 3.41Å; L329-Q406 HydrophobicContact CD2-CB 3.52Å; L329-Q406 HydrophobicContact CD2-CG 3.73Å; L358-Q406 CarbonylContact C-O 3.59Å; L358-Q406 WeakPolarHBondContact CA-O 3.45Å; I359-Q406 HydrophobicContact CB-CB 4.19Å; I359-Q406 PolarHBondContact N-O 3.27Å; I359-Q406 PolarHBondContact O-N 3.04Å; Q406-T408 PolarHBondContact NE2-OG1 2.85Å; Q406-T408 VanDerWaalsContact NE2-OG1 3.08Å
407G97.7Very high94.9Very high0 Ų043.9 Ų43.90%022%0.224CC..EExtended strand (participates in β ladder)trans-86.5140.8164.400000109.3A327 A328 R357A327-G407 VanDerWaalsContact CA-O 3.22Å; A327-G407 WeakPolarHBondContact CA-O 3.45Å; A328-G407 PolarHBondContact N-O 2.93Å; A328-G407 PolarHBondContact O-N 3.22Å; R357-G407 CarbonylContact O-C 3.55Å; R357-G407 WeakPolarHBondContact O-CA 3.13Å
408T97.4Very high94.8Very high2 Ų243.4 Ų43.41%0.01222%0.222CC..EExtended strand (participates in β ladder)trans-137.4129.6177.8-57.90000110.4E326 R357 Q406E326-T408 WeakPolarHBondContact O-CA 3.47Å; R357-T408 PolarHBondContact N-O 3.09Å; R357-T408 VanDerWaalsContact NH2-CG2 3.35Å; R357-T408 PolarHBondContact O-N 3.04Å; Q406-T408 PolarHBondContact NE2-OG1 2.85Å; Q406-T408 VanDerWaalsContact NE2-OG1 3.08Å
409K96.9Very high95Very high7 Ų737.1 Ų37.13%0.0319%0.193CC..  trans-73.3128.3179-54.6-175.4-170.9170.40110S318 T319 S321 E325 E326 P412S318-K409 VanDerWaalsContact O-CE 3.3Å; S318-K409 WeakPolarHBondContact O-CE 3.26Å; T319-K409 HydrophobicContact CG2-CG 4.08Å; S321-K409 WeakPolarHBondContact O-CD 3.13Å; S321-K409 WeakPolarHBondContact O-CE 3.46Å; S321-K409 PolarHBondContact O-NZ 3.28Å; E325-K409 WeakPolarHBondContact CA-O 3.22Å; E325-K409 PolarHBondContact N-O 3.43Å; E326-K409 HydrophobicContact CB-CD 4.07Å; E326-K409 HydrophobicContact CB-CG 4.42Å; E326-K409 PolarHBondContact O-N 2.81Å; E326-K409 IonicContact OE2-NZ 2.76Å; E326-K409 PolarHBondContact OE2-NZ 3.45Å; K409-P412 HydrophobicContact CB-CG 4.08Å; K409-P412 HydrophobicContact CD-CG 4.39Å
410G95.4Very high95.1Very high12 Ų1232.1 Ų32.112%0.12417%0.169CC..SBendtrans-92.7-66.5178.900000112.4A324 S355 D356A324-G410 WeakPolarHBondContact CB-O 3.39Å; S355-G410 WeakPolarHBondContact O-CA 3.44Å; D356-G410 PolarHBondContact OD1-N 2.87Å
411D94.3Very high95.2Very high50 Ų5029.1 Ų29.127%0.26716%0.156SC..  trans-133.584.4-180-177.78.2000111Q413 N414 S415D411-Q413 PolarHBondContact O-N 2.93Å; D411-Q413 PolarHBondContact OD1-N 3.17Å; D411-N414 PolarHBondContact O-N 2.9Å; D411-N414 PolarHBondContact OD2-ND2 2.89Å; D411-S415 WeakPolarHBondContact O-CB 3.01Å; D411-S415 PolarHBondContact O-N 2.96Å; D411-S415 VanDerWaalsContact O-N 3.1Å
412P92Very high95.2Very high12 Ų1229.1 Ų29.18%0.07816%0.156CC..THydrogen-bonded Turntrans-61-24.4-178.9-24.834.1000114.5T319 K409 N414 S415T319-P412 WeakPolarHBondContact O-CA 3.37Å; K409-P412 HydrophobicContact CB-CG 4.08Å; K409-P412 HydrophobicContact CD-CG 4.39Å; P412-N414 VanDerWaalsContact C-N 3.26Å; P412-N414 PolarHBondContact O-N 2.91Å; P412-S415 PolarHBondContact O-N 2.85Å
413Q91.2Very high95.2Very high167 Ų16727 Ų2778%0.7815%0.148SC*.THydrogen-bonded Turntrans-70.4-26.7-178.4-63.4-61.7-35.800112.3D411D411-Q413 PolarHBondContact O-N 2.93Å; D411-Q413 PolarHBondContact OD1-N 3.17Å
414N90.3Very high95.2Very high123 Ų12327 Ų2766%0.65815%0.148SC*.SBendtrans-113.98.3178.5-64.1-47.6000112.7D411 P412D411-N414 PolarHBondContact O-N 2.9Å; D411-N414 PolarHBondContact OD2-ND2 2.89Å; P412-N414 VanDerWaalsContact C-N 3.26Å; P412-N414 PolarHBondContact O-N 2.91Å
415S91.7Very high95.2Very high8 Ų827 Ų276%0.05615%0.148CC..  trans-91.7135.7175.4-178.90000110.7T319 S320 G352 S353 D411 P412T319-S415 WeakPolarHBondContact O-CB 3.09Å; T319-S415 PolarHBondContact OG1-OG 2.91Å; S320-S415 WeakPolarHBondContact CA-O 3.05Å; S320-S415 WeakPolarHBondContact CB-O 3.19Å; G352-S415 WeakPolarHBondContact CA-OG 3.22Å; S353-S415 PolarHBondContact N-OG 2.83Å; D411-S415 WeakPolarHBondContact O-CB 3.01Å; D411-S415 PolarHBondContact O-N 2.96Å; D411-S415 VanDerWaalsContact O-N 3.1Å; P412-S415 PolarHBondContact O-N 2.85Å
416T88.9Confident95.2Very high134 Ų13427 Ų2782%0.82215%0.148SC*.  trans-115.9-0.5176.458.30000113.2
417G91.9Very high95.2Very high7 Ų725.8 Ų25.87%0.07214%0.143CC..SBendtrans-139.1-133.1-170.200000113.2T319 S320 T351T319-G417 PolarHBondContact N-O 3.33Å; T319-G417 PolarHBondContact OG1-O 3.06Å; S320-G417 PolarHBondContact N-O 2.83Å; T351-G417 VanDerWaalsContact OG1-CA 3.31Å; T351-G417 WeakPolarHBondContact OG1-CA 3.36Å
418G94.1Very high95.2Very high0 Ų025.9 Ų25.90%014%0.144CC..EExtended strand (participates in β ladder)trans-168.7-168.1-175.700000114.8L317 M350 T351 Y420L317-G418 CarbonylContact O-C 3.46Å; L317-G418 WeakPolarHBondContact O-CA 3.3Å; M350-G418 CarbonylContact C-O 3.59Å; M350-G418 WeakPolarHBondContact CA-O 3.48Å; T351-G418 PolarHBondContact N-O 3.38Å; T351-G418 PolarHBondContact OG1-N 2.93Å; T351-G418 VanDerWaalsContact OG1-N 3.12Å; G418-Y420 VanDerWaalsContact C-CE2 3.48Å; G418-Y420 VanDerWaalsContact O-CE2 3.31Å; G418-Y420 WeakPolarHBondContact O-CE2 3.32Å
419I96.3Very high95Very high0 Ų027.2 Ų27.20%015%0.152CC..EExtended strand (participates in β ladder)trans-110.2134173-49.9178.8000108W289 Q316 L317 T319 M350 D356 R357 L358W289-I419 HydrophobicContact CH2-CB 4.11Å; W289-I419 HydrophobicContact CH2-CG2 3.75Å; W289-I419 HydrophobicContact CZ3-CB 4.45Å; W289-I419 HydrophobicContact CZ3-CG2 4.34Å; W289-I419 WeakPolarHBondContact CZ3-O 3.33Å; Q316-I419 CarbonylContact C-O 3.56Å; Q316-I419 WeakPolarHBondContact CA-O 2.97Å; L317-I419 HydrophobicContact CB-CB 4.39Å; L317-I419 HydrophobicContact CD2-CD1 4.33Å; L317-I419 PolarHBondContact N-O 3.13Å; L317-I419 PolarHBondContact O-N 2.95Å; T319-I419 HydrophobicContact CG2-CD1 4.41Å; T319-I419 HydrophobicContact CG2-CG1 4.04Å; M350-I419 HydrophobicContact CE-CD1 4.45Å; M350-I419 HydrophobicContact CE-CG2 4.03Å; M350-I419 HydrophobicContact CG-CG1 4.31Å; M350-I419 HydrophobicContact CG-CG2 4.15Å; D356-I419 HydrophobicContact CB-CD1 4.29Å; D356-I419 HydrophobicContact CB-CG1 4.46Å; R357-I419 WeakPolarHBondContact O-CD1 3.46Å; L358-I419 HydrophobicContact CB-CG2 4.28Å; L358-I419 HydrophobicContact CD1-CG2 4.43Å
420Y96.1Very high94.9Very high4 Ų431 Ų312%0.01618%0.177CC..EExtended strand (participates in β ladder)trans-125.2142.8-174.6-52.9-111000109.3E299 F314 M315 Q316 Y348 K349 T351 G418E299-Y420 HydrophobicContact CG-CE1 4.4Å; F314-Y420 AromaticContact CD2-CD1 3.68Å; F314-Y420 HydrophobicContact CD2-CD1 3.68Å; F314-Y420 HydrophobicContact CD2-CE1 4.45Å; F314-Y420 AromaticContact CE2-CD1 3.34Å; F314-Y420 HydrophobicContact CE2-CD1 3.34Å; F314-Y420 AromaticContact CE2-CE1 3.67Å; F314-Y420 HydrophobicContact CE2-CE1 3.67Å; F314-Y420 HydrophobicContact CZ-CD1 4.2Å; F314-Y420 HydrophobicContact CZ-CE1 4.28Å; M315-Y420 CarbonylContact O-C 3.55Å; M315-Y420 WeakPolarHBondContact O-CA 3.31Å; Q316-Y420 HydrophobicContact CB-CD1 4.45Å; Q316-Y420 HydrophobicContact CG-CD1 3.95Å; Q316-Y420 HydrophobicContact CG-CE1 3.63Å; Q316-Y420 VanDerWaalsContact NE2-CE1 3.3Å; Q316-Y420 PolarHBondContact NE2-OH 2.81Å; Y348-Y420 WeakPolarHBondContact CA-O 3.31Å; Y348-Y420 WeakPolarHBondContact CB-O 3.43Å; K349-Y420 HydrophobicContact CB-CD2 4.22Å; K349-Y420 HydrophobicContact CB-CG 4.37Å; K349-Y420 HydrophobicContact CD-CD2 4.47Å; K349-Y420 HydrophobicContact CG-CD2 4.36Å; K349-Y420 PolarHBondContact N-O 2.85Å; K349-Y420 VanDerWaalsContact N-O 3.09Å; K349-Y420 WeakPolarHBondContact O-CD2 3.35Å; K349-Y420 PolarHBondContact O-N 3.14Å; T351-Y420 HydrophobicContact CG2-CE2 4.09Å; T351-Y420 VanDerWaalsContact OG1-CE2 3.28Å; T351-Y420 WeakPolarHBondContact OG1-CE2 3.48Å; T351-Y420 PolarHBondContact OG1-OH 3.04Å; G418-Y420 VanDerWaalsContact C-CE2 3.48Å; G418-Y420 VanDerWaalsContact O-CE2 3.31Å; G418-Y420 WeakPolarHBondContact O-CE2 3.32Å
421L97.3Very high95Very high0 Ų031.1 Ų31.10%018%0.176CC..EExtended strand (participates in β ladder)trans-132.8136.2177.1-66.9172.4000110.2W289 M315 L330 F346 L358 F405W289-L421 HydrophobicContact CE3-CD1 4.25Å; W289-L421 HydrophobicContact CH2-CD1 3.37Å; W289-L421 HydrophobicContact CH2-CG 3.67Å; W289-L421 HydrophobicContact CZ2-CD1 3.78Å; W289-L421 HydrophobicContact CZ3-CB 4.4Å; W289-L421 HydrophobicContact CZ3-CD1 3.64Å; W289-L421 HydrophobicContact CZ3-CG 3.74Å; M315-L421 HydrophobicContact CB-CB 4.36Å; M315-L421 PolarHBondContact N-O 2.74Å; M315-L421 PolarHBondContact O-N 3.3Å; L330-L421 HydrophobicContact CD2-CD1 4.48Å; F346-L421 HydrophobicContact CD2-CD2 3.88Å; F346-L421 HydrophobicContact CE2-CD2 4.12Å; L358-L421 HydrophobicContact CD1-CD1 4.42Å; L358-L421 HydrophobicContact CD1-CD2 4.26Å; L358-L421 HydrophobicContact CD2-CD2 3.7Å; F405-L421 HydrophobicContact CB-CD1 3.65Å; F405-L421 HydrophobicContact CD1-CD1 4.04Å; F405-L421 HydrophobicContact CD1-CD2 4.22Å; F405-L421 HydrophobicContact CD2-CD1 3.8Å; F405-L421 HydrophobicContact CE1-CD2 4.34Å; F405-L421 HydrophobicContact CE2-CD1 4.41Å; F405-L421 HydrophobicContact CG-CD1 3.56Å
422D97.3Very high95Very high0 Ų030 Ų300%017%0.172CC..EExtended strand (participates in β ladder)trans-155.4170174.7-159.48.9000111.7H302 T303 F314 F347 W388 I424H302-D422 WeakPolarHBondContact CA-OD2 3.36Å; H302-D422 HydrophobicContact CB-CB 3.97Å; H302-D422 PolarHBondContact N-OD2 3.22Å; T303-D422 PolarHBondContact N-OD2 2.96Å; T303-D422 PolarHBondContact OG1-OD1 2.97Å; T303-D422 PolarHBondContact OG1-OD2 2.93Å; T303-D422 VanDerWaalsContact OG1-OD2 3.13Å; F314-D422 HydrophobicContact CB-CB 4.24Å; F347-D422 PolarHBondContact N-O 2.92Å; F347-D422 PolarHBondContact O-N 3.47Å; W388-D422 HydrophobicContact CH2-CB 3.72Å; W388-D422 HydrophobicContact CZ2-CB 4.49Å; W388-D422 HydrophobicContact CZ3-CB 4.01Å; D422-I424 VanDerWaalsContact C-N 3.34Å; D422-I424 PolarHBondContact O-N 2.68Å
423D97.1Very high95.2Very high1 Ų131.5 Ų31.51%0.00518%0.181CC..EExtended strand (participates in β ladder)trans49.948.1172.7-77-19.6000114T270 H302 T303 F347 P515 K583T270-D423 WeakPolarHBondContact CG2-OD1 3.25Å; H302-D423 IonicContact CE1-OD2 2.83Å; H302-D423 IonicContact CG-OD2 3.75Å; H302-D423 IonicContact ND1-OD2 3.46Å; H302-D423 PolarHBondContact ND1-OD2 2.96Å; T303-D423 PolarHBondContact OG1-OD1 3.18Å; F347-D423 HydrophobicContact CB-CB 4.48Å; F347-D423 HydrophobicContact CD2-CB 3.68Å; F347-D423 HydrophobicContact CE2-CB 4.41Å; F347-D423 HydrophobicContact CG-CB 4.47Å; D423-P515 WeakPolarHBondContact OD1-CB 3.37Å; D423-K583 IonicContact OD2-NZ 3.97Å; D423-K583 PolarHBondContact OD2-NZ 3.17Å
424I98.4Very high95.5Very high0 Ų023.6 Ų23.60%014%0.144CC..EExtended strand (participates in β ladder)trans-73.9133.3179.3-57.4159000109.6H268 C269 F271 M279 L344 Q345 F346 Y403 F405 D422H268-I424 CarbonylContact C-O 3.54Å; H268-I424 WeakPolarHBondContact CA-O 3.49Å; H268-I424 PolarHBondContact ND1-O 2.9Å; C269-I424 HydrophobicContact CB-CB 4.4Å; C269-I424 PolarHBondContact N-O 3.08Å; C269-I424 PolarHBondContact O-N 2.94Å; F271-I424 HydrophobicContact CE1-CD1 4.4Å; F271-I424 HydrophobicContact CE2-CD1 3.73Å; F271-I424 HydrophobicContact CE2-CG1 4.36Å; F271-I424 HydrophobicContact CZ-CD1 3.35Å; F271-I424 HydrophobicContact CZ-CG1 4.42Å; M279-I424 HydrophobicContact CE-CD1 4.36Å; M279-I424 HydrophobicContact SD-CD1 4.08Å; L344-I424 HydrophobicContact CD1-CG2 3.79Å; Q345-I424 CarbonylContact O-C 3.56Å; Q345-I424 WeakPolarHBondContact O-CA 3.37Å; F346-I424 HydrophobicContact CB-CB 4.3Å; F346-I424 HydrophobicContact CB-CG1 3.81Å; F346-I424 HydrophobicContact CB-CG2 4.45Å; Y403-I424 HydrophobicContact CE2-CG2 4.17Å; Y403-I424 WeakPolarHBondContact OH-CG2 3.36Å; F405-I424 HydrophobicContact CD2-CD1 4.49Å; F405-I424 HydrophobicContact CE2-CD1 3.62Å; F405-I424 HydrophobicContact CE2-CG1 4.16Å; F405-I424 HydrophobicContact CZ-CD1 4.22Å; F405-I424 HydrophobicContact CZ-CG1 4.26Å; F405-I424 HydrophobicContact CZ-CG2 4.49Å; D422-I424 VanDerWaalsContact C-N 3.34Å; D422-I424 PolarHBondContact O-N 2.68Å
425T98.2Very high95.9Very high2 Ų219.9 Ų19.91%0.01213%0.125CC..EExtended strand (participates in β ladder)trans-138.8131.8175.1-58.90000109.3L265 Q345 T427 V517L265-T425 HydrophobicContact CD1-CG2 3.94Å; Q345-T425 PolarHBondContact N-O 3.15Å; Q345-T425 PolarHBondContact O-N 3.45Å; T425-T427 HydrophobicContact CG2-CG2 3.96Å; T425-V517 HydrophobicContact CG2-CB 3.89Å; T425-V517 HydrophobicContact CG2-CG1 3.65Å; T425-V517 HydrophobicContact CG2-CG2 4.24Å
426L98.4Very high96.2Very high0 Ų020.5 Ų20.50%013%0.127CC..EExtended strand (participates in β ladder)trans-121.3114.1172.7179.672.7000109.5L266 D267 L335 Q342 L344 L395 F401 Y403L266-L426 HydrophobicContact CB-CB 4.48Å; L266-L426 HydrophobicContact CB-CD2 3.79Å; L266-L426 HydrophobicContact CB-CG 4.07Å; L266-L426 HydrophobicContact CD1-CD2 3.87Å; L266-L426 HydrophobicContact CD1-CG 4.26Å; L266-L426 HydrophobicContact CG-CD2 4.5Å; L266-L426 PolarHBondContact N-O 2.72Å; D267-L426 HydrophobicContact CB-CB 4Å; D267-L426 PolarHBondContact N-O 3.47Å; D267-L426 PolarHBondContact O-N 3.24Å; L335-L426 HydrophobicContact CD1-CD2 3.55Å; Q342-L426 HydrophobicContact CB-CD1 3.83Å; L344-L426 HydrophobicContact CB-CD1 3.85Å; L344-L426 HydrophobicContact CD1-CB 4.25Å; L344-L426 HydrophobicContact CD1-CD1 4.23Å; L395-L426 HydrophobicContact CD1-CD1 3.92Å; F401-L426 HydrophobicContact CE2-CD2 4.4Å; F401-L426 HydrophobicContact CZ-CD2 3.9Å; Y403-L426 HydrophobicContact CD1-CD2 4.03Å; Y403-L426 HydrophobicContact CE1-CB 4.4Å; Y403-L426 HydrophobicContact CE1-CD2 4.08Å
427T97.9Very high96.6Very high13 Ų1316.5 Ų16.58%0.0810%0.102CC..EExtended strand (participates in β ladder)trans-114.4151.9176.257.30000111.3L104 T264 L265 Q342 C343 T425 T429L104-T427 HydrophobicContact CD1-CG2 3.59Å; T264-T427 CarbonylContact O-C 3.58Å; T264-T427 VanDerWaalsContact O-CA 3.27Å; T264-T427 WeakPolarHBondContact O-CA 3.11Å; L265-T427 HydrophobicContact CD1-CG2 4.02Å; Q342-T427 CarbonylContact C-O 3.52Å; Q342-T427 WeakPolarHBondContact CA-O 3.15Å; Q342-T427 VanDerWaalsContact CB-O 3.29Å; Q342-T427 WeakPolarHBondContact CB-O 3.49Å; C343-T427 PolarHBondContact N-O 3.38Å; C343-T427 PolarHBondContact O-N 2.05Å; T425-T427 HydrophobicContact CG2-CG2 3.96Å; T427-T429 PolarHBondContact O-N 2.82Å; T427-T429 VanDerWaalsContact O-N 3.13Å; T427-T429 PolarHBondContact OG1-OG1 3.37Å
428E97.3Very high96.8Very high1 Ų116.4 Ų16.41%0.00510%0.1CC..SBendtrans-86.551.6171.5-53.6-153.386.300111T264 L266 P337 K338 R339 Q341 Q342T264-E428 HydrophobicContact CG2-CB 4.37Å; T264-E428 PolarHBondContact O-N 3.07Å; L266-E428 HydrophobicContact CD1-CG 3.54Å; L266-E428 HydrophobicContact CD2-CG 4.05Å; L266-E428 HydrophobicContact CG-CG 3.52Å; P337-E428 VanDerWaalsContact CA-OE1 3.22Å; P337-E428 WeakPolarHBondContact CA-OE1 3.34Å; P337-E428 VanDerWaalsContact CB-OE1 3.25Å; P337-E428 WeakPolarHBondContact CB-OE1 3.37Å; K338-E428 WeakPolarHBondContact CB-OE2 3.5Å; K338-E428 VanDerWaalsContact N-CD 3.25Å; K338-E428 PolarHBondContact N-OE1 3.09Å; K338-E428 PolarHBondContact N-OE2 3.23Å; R339-E428 HydrophobicContact CB-CB 4.07Å; R339-E428 WeakPolarHBondContact CD-O 3.43Å; R339-E428 HydrophobicContact CG-CB 4.15Å; R339-E428 PolarHBondContact N-OE1 3.24Å; R339-E428 PolarHBondContact NH1-O 2.82Å; Q341-E428 CarbonylContact O-C 3.56Å; Q341-E428 WeakPolarHBondContact O-CA 3.33Å; Q342-E428 HydrophobicContact CG-CG 4.12Å; Q342-E428 PolarHBondContact NE2-OE1 3.21Å
429T94.5Very high96.8Very high30 Ų3018.1 Ų18.118%0.18411%0.108CC..SBendtrans-126.8160.4178.860.40000109.6T264 Q342 C343 T427T264-T429 HydrophobicContact CG2-CG2 4.48Å; Q342-T429 CarbonylContact C-O 3.47Å; C343-T429 WeakPolarHBondContact CB-O 3.47Å; C343-T429 PolarHBondContact N-O 2.78Å; T427-T429 PolarHBondContact O-N 2.82Å; T427-T429 VanDerWaalsContact O-N 3.13Å; T427-T429 PolarHBondContact OG1-OG1 3.37Å
430P94.9Very high96.7Very high87 Ų8722.1 Ų22.157%0.56513%0.129SC*.PPolyproline II helixtrans-56.9149.8165.1-22.634.8000111.2
431C96.1Very high96.7Very high15 Ų1521.9 Ų21.910%0.10113%0.129CC..PPolyproline II helixtrans-80.1152.9167.1-71.90000110.1C343 H392 V394C343-C431 WeakPolarHBondContact CA-SG 3.46Å; C343-C431 HydrophobicContact CB-CB 4Å; C343-C431 WeakPolarHBondContact CB-SG 3.14Å; C343-C431 WeakPolarHBondContact SG-CA 3.46Å; C343-C431 WeakPolarHBondContact SG-CB 3.27Å; C343-C431 CovalentContact SG-SG 2.04Å; C343-C431 PolarHBondContact SG-SG 3.19Å; H392-C431 HydrophobicContact CB-CB 4.09Å; V394-C431 HydrophobicContact CG2-CB 3.78Å
432P96.1Very high96.5Very high26 Ų2624.3 Ų24.317%0.16915%0.145CC..PPolyproline II helixtrans-60.5138.5175.625.5-34.5000111.5H392 V435 F590 D592H392-P432 VanDerWaalsContact CD2-CD 3.49Å; H392-P432 WeakPolarHBondContact CD2-CD 3.45Å; P432-V435 HydrophobicContact CB-CG2 4.25Å; P432-V435 HydrophobicContact CG-CG2 3.74Å; P432-F590 HydrophobicContact CB-CB 3.87Å; P432-F590 HydrophobicContact CB-CD1 4.4Å; P432-F590 HydrophobicContact CB-CD2 4.33Å; P432-F590 HydrophobicContact CB-CG 3.98Å; P432-F590 HydrophobicContact CG-CD1 4.24Å; P432-F590 HydrophobicContact CG-CD2 4.28Å; P432-F590 HydrophobicContact CG-CE1 4.5Å; P432-F590 HydrophobicContact CG-CG 4.13Å; P432-D592 VanDerWaalsContact CA-OD1 3.23Å; P432-D592 WeakPolarHBondContact CA-OD1 3.41Å
433T95.8Very high96.4Very high44 Ų4429.3 Ų29.327%0.2717%0.169SC..SBendtrans-70.3-40.1-178.7-64.30000111.9Y460 N461 F467 D592 E594T433-Y460 WeakPolarHBondContact CG2-O 3.4Å; T433-N461 HydrophobicContact CG2-CB 4.37Å; T433-F467 HydrophobicContact CG2-CE1 4.05Å; T433-F467 HydrophobicContact CG2-CZ 3.72Å; T433-D592 PolarHBondContact N-OD1 2.75Å; T433-E594 PolarHBondContact OG1-OE1 2.82Å; T433-E594 VanDerWaalsContact OG1-OE1 3.08Å
434G96.8Very high96.3Very high1 Ų129.8 Ų29.81%0.0117%0.172CC..EExtended strand (participates in β ladder)trans-125.3139.4174.200000111.8F590 V591G434-F590 CarbonylContact O-C 3.57Å; G434-F590 WeakPolarHBondContact O-CA 3.29Å; G434-V591 PolarHBondContact N-O 3.45Å; G434-V591 PolarHBondContact O-N 3.01Å
435V98Very high96Very high44 Ų4431 Ų3127%0.26718%0.178SC..EExtended strand (participates in β ladder)trans-128.5125.5174.5-179.50000108.4I390 P432 F459 I588 M589 F590I390-V435 HydrophobicContact CG2-CG1 3.91Å; P432-V435 HydrophobicContact CB-CG2 4.25Å; P432-V435 HydrophobicContact CG-CG2 3.74Å; V435-F459 WeakPolarHBondContact O-CZ 3.3Å; V435-I588 HydrophobicContact CG1-CG2 4.25Å; V435-M589 WeakPolarHBondContact CA-O 3.42Å; V435-F590 HydrophobicContact CB-CD1 4.26Å; V435-F590 HydrophobicContact CB-CE1 4.47Å; V435-F590 HydrophobicContact CG1-CD1 3.94Å; V435-F590 HydrophobicContact CG1-CE1 3.79Å; V435-F590 HydrophobicContact CG2-CD1 3.81Å; V435-F590 HydrophobicContact CG2-CE1 4Å
436W98.1Very high95.8Very high22 Ų2238.6 Ų38.68%0.08321%0.213CC..EExtended strand (participates in β ladder)trans-126.7116.9177.9-178.326.9000110.5V438 L454 S456 F459 L469 L471 M589W436-V438 HydrophobicContact CD2-CG2 4.09Å; W436-V438 VanDerWaalsContact CE2-CG2 3.49Å; W436-V438 HydrophobicContact CH2-CG2 4.24Å; W436-V438 HydrophobicContact CZ2-CG2 3.59Å; W436-L454 HydrophobicContact CH2-CB 3.79Å; W436-L454 HydrophobicContact CZ2-CB 3.91Å; W436-S456 VanDerWaalsContact CD2-CB 3.47Å; W436-F459 HydrophobicContact CB-CZ 4.2Å; W436-L469 HydrophobicContact CE3-CB 3.97Å; W436-L469 HydrophobicContact CE3-CD1 4.3Å; W436-L469 HydrophobicContact CZ3-CB 4.02Å; W436-L471 HydrophobicContact CH2-CB 3.61Å; W436-L471 HydrophobicContact CH2-CD2 4.44Å; W436-L471 HydrophobicContact CZ3-CB 3.68Å; W436-M589 HydrophobicContact CD2-CE 3.64Å; W436-M589 HydrophobicContact CE3-CE 3.22Å; W436-M589 HydrophobicContact CE3-SD 3.98Å; W436-M589 HydrophobicContact CG-CE 4.27Å; W436-M589 HydrophobicContact CH2-CE 4.27Å; W436-M589 HydrophobicContact CZ3-CE 3.6Å; W436-M589 HydrophobicContact CZ3-SD 4.19Å; W436-M589 PolarHBondContact N-O 2.85Å; W436-M589 PolarHBondContact O-N 3.23Å
437T97.4Very high95.6Very high50 Ų5043.6 Ų43.631%0.30724%0.24SC..EExtended strand (participates in β ladder)trans-101.3127.6172.7-55.40000109.7Q439 D586 L587 I588T437-Q439 HydrophobicContact CG2-CG 4.21Å; T437-D586 HydrophobicContact CG2-CB 4.12Å; T437-L587 WeakPolarHBondContact CA-O 3.18Å; T437-I588 HydrophobicContact CG2-CG1 4.06Å
438V96.9Very high95.4Very high5 Ų543.6 Ų43.63%0.0324%0.24CC..EExtended strand (participates in β ladder)trans-108.2107.7169.5-174.10000107.9W436 F441 V444 L454 L471 L587 M589W436-V438 HydrophobicContact CD2-CG2 4.09Å; W436-V438 VanDerWaalsContact CE2-CG2 3.49Å; W436-V438 HydrophobicContact CH2-CG2 4.24Å; W436-V438 HydrophobicContact CZ2-CG2 3.59Å; V438-F441 HydrophobicContact CB-CD2 4.12Å; V438-F441 HydrophobicContact CG1-CD2 3.73Å; V438-F441 HydrophobicContact CG1-CE2 4.29Å; V438-V444 HydrophobicContact CG1-CG2 4.1Å; V438-L454 HydrophobicContact CG1-CD2 4.17Å; V438-L471 HydrophobicContact CG2-CD2 4.3Å; V438-L587 HydrophobicContact CB-CB 4.43Å; V438-L587 PolarHBondContact N-O 3.08Å; V438-L587 PolarHBondContact O-N 2.71Å; V438-M589 HydrophobicContact CG2-CE 3.65Å
439Q94.4Very high95.1Very high35 Ų3547.2 Ų47.216%0.16427%0.265CS..SBendtrans-80.4157.5179.7-63171.3-33.400111.7D385 T437 F441 D586D385-Q439 PolarHBondContact OD1-NE2 3.05Å; D385-Q439 PolarHBondContact OD2-NE2 2.63Å; T437-Q439 HydrophobicContact CG2-CG 4.21Å; Q439-F441 VanDerWaalsContact C-N 3.26Å; Q439-F441 PolarHBondContact O-N 3.08Å; Q439-D586 VanDerWaalsContact CA-OD1 3.27Å; Q439-D586 WeakPolarHBondContact CA-OD1 3.41Å; Q439-D586 WeakPolarHBondContact CB-OD1 3.38Å; Q439-D586 WeakPolarHBondContact CG-OD1 3.35Å
440N94.1Very high94.9Very high84 Ų8452.1 Ų52.145%0.44928%0.284SS..SBendtrans51.145.7179.7-60.6-52.1000112.4S442 Q443 V444 D585N440-S442 PolarHBondContact O-N 2.81Å; N440-Q443 HydrophobicContact CB-CB 4.35Å; N440-Q443 WeakPolarHBondContact O-CB 3.48Å; N440-Q443 PolarHBondContact O-N 3.44Å; N440-V444 PolarHBondContact O-N 2.83Å; N440-V444 VanDerWaalsContact O-N 3.11Å; N440-D585 WeakPolarHBondContact CA-OD2 3.36Å; N440-D585 PolarHBondContact N-O 2.79Å; N440-D585 VanDerWaalsContact N-O 3.15Å
441F95.4Very high94.5Very high0 Ų049 Ų490%027%0.268CS..Hα-helixtrans-63.6-29.8-170.3-165.8-103.9000113.1V438 Q439 Q443 V444 L445 L471 P473 L482 L576 L582 D585 L587V438-F441 HydrophobicContact CB-CD2 4.12Å; V438-F441 HydrophobicContact CG1-CD2 3.73Å; V438-F441 HydrophobicContact CG1-CE2 4.29Å; Q439-F441 VanDerWaalsContact C-N 3.26Å; Q439-F441 PolarHBondContact O-N 3.08Å; F441-Q443 VanDerWaalsContact C-N 3.3Å; F441-Q443 PolarHBondContact O-N 2.52Å; F441-V444 HydrophobicContact CD2-CB 4.14Å; F441-V444 HydrophobicContact CD2-CG1 4.34Å; F441-V444 HydrophobicContact CE2-CB 4.34Å; F441-V444 HydrophobicContact CE2-CG1 4.07Å; F441-V444 WeakPolarHBondContact O-CB 3.19Å; F441-V444 PolarHBondContact O-N 2.55Å; F441-V444 VanDerWaalsContact O-N 3.14Å; F441-L445 HydrophobicContact CD1-CD1 3.92Å; F441-L445 HydrophobicContact CD1-CG 4.07Å; F441-L445 HydrophobicContact CE1-CD1 3.74Å; F441-L445 HydrophobicContact CE1-CD2 3.94Å; F441-L445 HydrophobicContact CE1-CG 3.67Å; F441-L445 HydrophobicContact CZ-CD2 4.23Å; F441-L445 HydrophobicContact CZ-CG 4.23Å; F441-L445 PolarHBondContact O-N 3.2Å; F441-L471 HydrophobicContact CE2-CD2 3.63Å; F441-L471 HydrophobicContact CZ-CD2 4.15Å; F441-P473 HydrophobicContact CZ-CB 4.27Å; F441-L482 HydrophobicContact CE1-CD2 3.74Å; F441-L482 HydrophobicContact CZ-CD2 3.42Å; F441-L482 VanDerWaalsContact CZ-CD2 3.42Å; F441-L576 HydrophobicContact CD1-CD1 4.34Å; F441-L576 HydrophobicContact CE1-CD1 3.81Å; F441-L582 HydrophobicContact CB-CD2 3.9Å; F441-L582 HydrophobicContact CD1-CD1 4.09Å; F441-L582 HydrophobicContact CD1-CD2 3.62Å; F441-L582 HydrophobicContact CG-CD2 3.97Å; F441-D585 WeakPolarHBondContact CB-O 3.46Å; F441-D585 PolarHBondContact N-O 3.12Å; F441-D585 PolarHBondContact N-OD2 2.91Å; F441-L587 HydrophobicContact CB-CB 4.19Å; F441-L587 HydrophobicContact CD1-CB 4.45Å; F441-L587 HydrophobicContact CD1-CD2 4.36Å; F441-L587 HydrophobicContact CD2-CB 3.98Å; F441-L587 HydrophobicContact CD2-CD2 3.88Å; F441-L587 HydrophobicContact CE1-CD2 4.12Å; F441-L587 HydrophobicContact CE2-CD2 3.65Å; F441-L587 HydrophobicContact CG-CB 3.91Å; F441-L587 HydrophobicContact CG-CD2 4.25Å; F441-L587 HydrophobicContact CZ-CD2 3.78Å
442S93.4Very high94.4Very high50 Ų5048.9 Ų48.935%0.3527%0.266SS..Hα-helixtrans-60.4-41.8172.6-64.30000111.2N440 V444 L445 E446 D585N440-S442 PolarHBondContact O-N 2.81Å; S442-V444 VanDerWaalsContact C-N 3.34Å; S442-L445 WeakPolarHBondContact O-CB 3.5Å; S442-L445 PolarHBondContact O-N 3.04Å; S442-E446 WeakPolarHBondContact O-CG 3.49Å; S442-E446 PolarHBondContact O-N 3.37Å; S442-D585 VanDerWaalsContact CB-OD1 3.23Å; S442-D585 WeakPolarHBondContact CB-OD1 3.47Å; S442-D585 VanDerWaalsContact CB-OD2 3.32Å; S442-D585 WeakPolarHBondContact CB-OD2 2.95Å; S442-D585 PolarHBondContact N-OD1 3.01Å; S442-D585 PolarHBondContact N-OD2 3.09Å; S442-D585 VanDerWaalsContact N-OD2 3.08Å; S442-D585 PolarHBondContact OG-OD1 3.04Å
443Q94.9Very high94.2Very high106 Ų10648.3 Ų48.350%0.49526%0.261SS..Hα-helixtrans-67.8-35.3174.8-171179.923.200111.9N440 F441 L445 E446 N447N440-Q443 HydrophobicContact CB-CB 4.35Å; N440-Q443 WeakPolarHBondContact O-CB 3.48Å; N440-Q443 PolarHBondContact O-N 3.44Å; F441-Q443 VanDerWaalsContact C-N 3.3Å; F441-Q443 PolarHBondContact O-N 2.52Å; Q443-L445 VanDerWaalsContact C-N 3.32Å; Q443-L445 PolarHBondContact O-N 2.99Å; Q443-E446 PolarHBondContact O-N 3.21Å; Q443-N447 WeakPolarHBondContact CG-ND2 3.43Å; Q443-N447 WeakPolarHBondContact O-CB 3.4Å; Q443-N447 PolarHBondContact O-N 3.49Å
444V95.1Very high94.2Very high11 Ų1146.8 Ų46.87%0.06725%0.251CS..Hα-helixtrans-59.7-45172.4175.40000110.4I24 V438 N440 F441 S442 E446 N447 T448 L454 P473I24-V444 HydrophobicContact CD1-CG2 4.23Å; V438-V444 HydrophobicContact CG1-CG2 4.1Å; N440-V444 PolarHBondContact O-N 2.83Å; N440-V444 VanDerWaalsContact O-N 3.11Å; F441-V444 HydrophobicContact CD2-CB 4.14Å; F441-V444 HydrophobicContact CD2-CG1 4.34Å; F441-V444 HydrophobicContact CE2-CB 4.34Å; F441-V444 HydrophobicContact CE2-CG1 4.07Å; F441-V444 WeakPolarHBondContact O-CB 3.19Å; F441-V444 PolarHBondContact O-N 2.55Å; F441-V444 VanDerWaalsContact O-N 3.14Å; S442-V444 VanDerWaalsContact C-N 3.34Å; V444-E446 VanDerWaalsContact C-N 3.33Å; V444-E446 PolarHBondContact O-N 2.75Å; V444-N447 PolarHBondContact O-N 3.38Å; V444-T448 HydrophobicContact CG1-CG2 4.18Å; V444-T448 WeakPolarHBondContact O-CB 3.4Å; V444-T448 VanDerWaalsContact O-CG2 3.29Å; V444-T448 WeakPolarHBondContact O-CG2 3.45Å; V444-T448 PolarHBondContact O-N 3Å; V444-T448 PolarHBondContact O-OG1 3.06Å; V444-L454 HydrophobicContact CG1-CD1 3.65Å; V444-L454 HydrophobicContact CG1-CD2 4Å; V444-L454 HydrophobicContact CG1-CG 4.45Å; V444-L454 HydrophobicContact CG2-CD2 4.48Å; V444-P473 HydrophobicContact CG1-CB 4.44Å; V444-P473 HydrophobicContact CG1-CG 3.82Å
445L93Very high94Very high25 Ų2548.3 Ų48.313%0.13126%0.258CS..Hα-helixtrans-63.2-36.9176.1-72.3170000112.5F441 S442 Q443 P473 H474F441-L445 HydrophobicContact CD1-CD1 3.92Å; F441-L445 HydrophobicContact CD1-CG 4.07Å; F441-L445 HydrophobicContact CE1-CD1 3.74Å; F441-L445 HydrophobicContact CE1-CD2 3.94Å; F441-L445 HydrophobicContact CE1-CG 3.67Å; F441-L445 HydrophobicContact CZ-CD2 4.23Å; F441-L445 HydrophobicContact CZ-CG 4.23Å; F441-L445 PolarHBondContact O-N 3.2Å; S442-L445 WeakPolarHBondContact O-CB 3.5Å; S442-L445 PolarHBondContact O-N 3.04Å; Q443-L445 VanDerWaalsContact C-N 3.32Å; Q443-L445 PolarHBondContact O-N 2.99Å; L445-P473 HydrophobicContact CD2-CB 3.8Å; L445-H474 PolarHBondContact O-CE1 2.67Å; L445-H474 PolarHBondContact O-NE2 3.17Å
446E93.4Very high94Very high161 Ų16146.5 Ų46.575%0.75225%0.247SC*.Hα-helixtrans-71.4-37.2177.6-71.8178.1179.300113.1S442 Q443 V444S442-E446 WeakPolarHBondContact O-CG 3.49Å; S442-E446 PolarHBondContact O-N 3.37Å; Q443-E446 PolarHBondContact O-N 3.21Å; V444-E446 VanDerWaalsContact C-N 3.33Å; V444-E446 PolarHBondContact O-N 2.75Å
447N94Very high93.8Very high105 Ų10549.2 Ų49.256%0.56127%0.268SS*.Hα-helixtrans-88.6-12.4-174.3-72.6-18.1000114.1Q443 V444Q443-N447 WeakPolarHBondContact CG-ND2 3.43Å; Q443-N447 WeakPolarHBondContact O-CB 3.4Å; Q443-N447 PolarHBondContact O-N 3.49Å; V444-N447 PolarHBondContact O-N 3.38Å
448T92.9Very high93.7Very high14 Ų1451.3 Ų51.39%0.08627%0.27CS..  trans-104.2155178.857.50000111.3V444 D452 P473 H474V444-T448 HydrophobicContact CG1-CG2 4.18Å; V444-T448 WeakPolarHBondContact O-CB 3.4Å; V444-T448 VanDerWaalsContact O-CG2 3.29Å; V444-T448 WeakPolarHBondContact O-CG2 3.45Å; V444-T448 PolarHBondContact O-N 3Å; V444-T448 PolarHBondContact O-OG1 3.06Å; T448-D452 HydrophobicContact CG2-CB 4.17Å; T448-P473 HydrophobicContact CG2-CG 4.31Å; T448-H474 PolarHBondContact O-CD2 3.22Å; T448-H474 PolarHBondContact O-NE2 2.96Å; T448-H474 VanDerWaalsContact O-NE2 3.1Å; T448-H474 PolarHBondContact OG1-CD2 3.26Å
449S91.4Very high93.7Very high76 Ų7652.5 Ų52.553%0.53128%0.275SS..  trans-121.9174.3174.2-69.70000109.9G451 D452S449-G451 PolarHBondContact O-N 2.79Å; S449-D452 PolarHBondContact N-OD2 2.99Å; S449-D452 WeakPolarHBondContact O-CB 3.44Å; S449-D452 PolarHBondContact O-N 2.96Å
450K90Very high93.8Very high134 Ų13454.7 Ų54.758%0.58328%0.282SS*.THydrogen-bonded Turntrans-51131.6175.367.4-175.2-177.7-179.30112D452K450-D452 VanDerWaalsContact C-N 3.25Å; K450-D452 PolarHBondContact O-N 3.14Å
451G87.6Confident93.8Very high21 Ų2151.2 Ų51.222%0.21626%0.263CS..THydrogen-bonded Turntrans81.1-9.2-179.600000115.4S449 G475S449-G451 PolarHBondContact O-N 2.79Å; G451-G475 PolarHBondContact N-O 3.26Å
452D92.6Very high93.8Very high12 Ų1255.9 Ų55.96%0.06430%0.296CS..  trans-69.7146.8169.4-63.4-24.5000109.6Y26 T448 S449 K450 P473Y26-D452 HydrophobicContact CE2-CB 4.14Å; Y26-D452 PolarHBondContact OH-OD1 3.17Å; Y26-D452 PolarHBondContact OH-OD2 2.74Å; T448-D452 HydrophobicContact CG2-CB 4.17Å; S449-D452 PolarHBondContact N-OD2 2.99Å; S449-D452 WeakPolarHBondContact O-CB 3.44Å; S449-D452 PolarHBondContact O-N 2.96Å; K450-D452 VanDerWaalsContact C-N 3.25Å; K450-D452 PolarHBondContact O-N 3.14Å; D452-P473 WeakPolarHBondContact O-CD 3.43Å
453K92.7Very high93.9Very high15 Ų1556.8 Ų56.87%0.06530%0.295CS..BIsolated β-bridgetrans-137.5150.8-173.165.7-173.8-178.9-179.90113.3T470 L471 Y472K453-T470 HydrophobicContact CB-CG2 3.86Å; K453-T470 HydrophobicContact CD-CG2 3.86Å; K453-T470 HydrophobicContact CG-CG2 4.3Å; K453-L471 CarbonylContact C-O 3.25Å; K453-L471 VanDerWaalsContact CA-O 3.25Å; K453-L471 WeakPolarHBondContact CA-O 3.47Å; K453-Y472 HydrophobicContact CB-CD1 3.8Å; K453-Y472 HydrophobicContact CB-CE1 3.64Å; K453-Y472 HydrophobicContact CB-CG 4.29Å; K453-Y472 HydrophobicContact CD-CE1 3.88Å; K453-Y472 WeakPolarHBondContact CD-OH 3.37Å; K453-Y472 HydrophobicContact CG-CE1 4.33Å
454L94.9Very high94Very high12 Ų1252.2 Ų52.26%0.06328%0.276CS..EExtended strand (participates in β ladder)trans-114.3147.6167.5-59.498.4000108.6I24 W436 V438 V444 T470 L471 P473I24-L454 HydrophobicContact CG2-CD2 3.57Å; W436-L454 HydrophobicContact CH2-CB 3.79Å; W436-L454 HydrophobicContact CZ2-CB 3.91Å; V438-L454 HydrophobicContact CG1-CD2 4.17Å; V444-L454 HydrophobicContact CG1-CD1 3.65Å; V444-L454 HydrophobicContact CG1-CD2 4Å; V444-L454 HydrophobicContact CG1-CG 4.45Å; V444-L454 HydrophobicContact CG2-CD2 4.48Å; L454-T470 CarbonylContact O-C 3.52Å; L454-T470 WeakPolarHBondContact O-CA 3.45Å; L454-L471 HydrophobicContact CB-CB 4.42Å; L454-L471 HydrophobicContact CD1-CD2 4.35Å; L454-L471 HydrophobicContact CD1-CG 4.49Å; L454-L471 PolarHBondContact N-O 3.16Å; L454-L471 PolarHBondContact O-N 3.27Å; L454-P473 HydrophobicContact CD1-CG 3.26Å
455Q94.6Very high94.1Very high32 Ų3251.8 Ų51.815%0.1527%0.274CS..EExtended strand (participates in β ladder)trans-120.8138.9178.1-69.9179.7-41.100110L469 T470 R561Q455-L469 WeakPolarHBondContact CA-O 3.5Å; Q455-T470 HydrophobicContact CG-CG2 4.27Å; Q455-R561 VanDerWaalsContact OE1-CZ 3.29Å
456S96.5Very high94.3Very high6 Ų650.6 Ų50.64%0.04227%0.267CS..PPolyproline II helixtrans-69.9164.7174.277.60000111.2W436 F459 G468 L469W436-S456 VanDerWaalsContact CD2-CB 3.47Å; S456-F459 WeakPolarHBondContact OG-CE2 3.34Å; S456-G468 WeakPolarHBondContact OG-CA 3.49Å; S456-L469 PolarHBondContact N-O 3.44Å; S456-L469 PolarHBondContact OG-N 3.44Å
457P94.4Very high94.5Very high80 Ų8043 Ų4352%0.51923%0.231SC..PPolyproline II helixtrans-55.2160.8157.6-21.934.3000111.6F459P457-F459 HydrophobicContact CB-CZ 4.5Å; P457-F459 WeakPolarHBondContact O-CE2 3.34Å
458R95.1Very high94.7Very high94 Ų9438 Ų3836%0.35521%0.205SC..PPolyproline II helixtrans-79125.2172.6-178.1172.561.6-169.2-6.6109.8Y460 F467 C489 S490R458-Y460 HydrophobicContact CG-CE2 4.4Å; R458-Y460 VanDerWaalsContact CZ-OH 3.32Å; R458-Y460 PolarHBondContact NE-OH 3.47Å; R458-F467 WeakPolarHBondContact CA-O 3.38Å; R458-C489 HydrophobicContact CG-CB 3.99Å; R458-S490 PolarHBondContact NH1-O 3.26Å
459F96.4Very high94.9Very high30 Ų3037.3 Ų37.313%0.13220%0.201CC..EExtended strand (participates in β ladder)trans-103167.5173.2-53.1-69000110.7V435 W436 S456 P457 G466 F467 V591V435-F459 WeakPolarHBondContact O-CZ 3.3Å; W436-F459 HydrophobicContact CB-CZ 4.2Å; S456-F459 WeakPolarHBondContact OG-CE2 3.34Å; P457-F459 HydrophobicContact CB-CZ 4.5Å; P457-F459 WeakPolarHBondContact O-CE2 3.34Å; F459-G466 CarbonylContact O-C 3.58Å; F459-G466 VanDerWaalsContact O-CA 3.31Å; F459-G466 WeakPolarHBondContact O-CA 3.39Å; F459-F467 HydrophobicContact CB-CD1 4.42Å; F459-F467 HydrophobicContact CB-CD2 4.19Å; F459-F467 HydrophobicContact CB-CE1 3.99Å; F459-F467 HydrophobicContact CB-CE2 3.75Å; F459-F467 HydrophobicContact CB-CZ 3.65Å; F459-F467 HydrophobicContact CD2-CD2 4.42Å; F459-F467 HydrophobicContact CD2-CE2 4.12Å; F459-F467 HydrophobicContact CG-CE2 4.33Å; F459-F467 PolarHBondContact N-O 2.7Å; F459-F467 PolarHBondContact O-N 3.48Å; F459-V591 HydrophobicContact CD2-CG1 4.01Å; F459-V591 HydrophobicContact CE2-CG1 4.11Å
460Y96.5Very high95.2Very high81 Ų8133.7 Ų33.732%0.31818%0.175SC..EExtended strand (participates in β ladder)trans-134136.8174.8-72.2-82.5000110.2T433 R458 G464 Y465T433-Y460 WeakPolarHBondContact CG2-O 3.4Å; R458-Y460 HydrophobicContact CG-CE2 4.4Å; R458-Y460 VanDerWaalsContact CZ-OH 3.32Å; R458-Y460 PolarHBondContact NE-OH 3.47Å; Y460-G464 WeakPolarHBondContact CD1-O 3.48Å; Y460-Y465 WeakPolarHBondContact CA-O 3.49Å
461N95.8Very high95.5Very high10 Ų1027.3 Ų27.35%0.05315%0.148CC..  trans-85.8177.5174.177.2-14.5000111.1T433 E463 G464 Y465 F467 F593T433-N461 HydrophobicContact CG2-CB 4.37Å; N461-E463 PolarHBondContact O-N 2.92Å; N461-E463 PolarHBondContact OD1-N 3.35Å; N461-G464 PolarHBondContact O-N 3.41Å; N461-G464 PolarHBondContact OD1-N 3.37Å; N461-Y465 PolarHBondContact N-O 3.07Å; N461-Y465 PolarHBondContact OD1-N 3.19Å; N461-F467 HydrophobicContact CB-CE1 3.91Å; N461-F593 HydrophobicContact CB-CB 4.38Å; N461-F593 HydrophobicContact CB-CD1 4.18Å; N461-F593 WeakPolarHBondContact CB-O 3.37Å; N461-F593 PolarHBondContact ND2-O 2.63Å
462S94Very high95.8Very high98 Ų9826.7 Ų26.769%0.68514%0.139SC*.THydrogen-bonded Turntrans-59-27.8-178.860.10000113.9E594S462-E594 PolarHBondContact OG-OE2 3.25Å
463E96.2Very high95.9Very high69 Ų6926.1 Ų26.132%0.32214%0.136SC..THydrogen-bonded Turntrans-82.9-21.3177.6-55.3-177.493.400113.1N461 Y465 L497 R504N461-E463 PolarHBondContact O-N 2.92Å; N461-E463 PolarHBondContact OD1-N 3.35Å; E463-Y465 HydrophobicContact CB-CD2 3.96Å; E463-Y465 HydrophobicContact CB-CE2 4.12Å; E463-L497 WeakPolarHBondContact O-CD2 3.33Å; E463-R504 IonicContact OE1-CZ 3.38Å; E463-R504 IonicContact OE1-NE 2.75Å; E463-R504 IonicContact OE1-NH2 3.45Å; E463-R504 PolarHBondContact OE1-NH2 2.91Å; E463-R504 IonicContact OE2-CZ 3.5Å; E463-R504 IonicContact OE2-NE 3.53Å; E463-R504 PolarHBondContact OE2-NE 2.97Å; E463-R504 IonicContact OE2-NH2 3.49Å
464G96.7Very high95.9Very high10 Ų1027.2 Ų27.210%0.10314%0.141CC..  trans102.610.4178.800000115.4Y460 N461 N493Y460-G464 WeakPolarHBondContact CD1-O 3.48Å; N461-G464 PolarHBondContact O-N 3.41Å; N461-G464 PolarHBondContact OD1-N 3.37Å; G464-N493 PolarHBondContact O-ND2 3.24Å; G464-N493 VanDerWaalsContact O-ND2 3.11Å
465Y97.9Very high95.6Very high3 Ų326.7 Ų26.71%0.01214%0.139CC..  trans-68.4128.7170.6-70.6-79.6000110.3Y460 N461 E463 L497 E498 W499 V501 F593Y460-Y465 WeakPolarHBondContact CA-O 3.49Å; N461-Y465 PolarHBondContact N-O 3.07Å; N461-Y465 PolarHBondContact OD1-N 3.19Å; E463-Y465 HydrophobicContact CB-CD2 3.96Å; E463-Y465 HydrophobicContact CB-CE2 4.12Å; Y465-L497 HydrophobicContact CD1-CB 4.41Å; Y465-L497 HydrophobicContact CD1-CD1 3.63Å; Y465-L497 HydrophobicContact CD1-CG 4.49Å; Y465-L497 HydrophobicContact CD2-CD1 4.43Å; Y465-L497 HydrophobicContact CD2-CD2 4.48Å; Y465-L497 HydrophobicContact CE1-CB 3.72Å; Y465-L497 HydrophobicContact CE1-CD1 3.82Å; Y465-L497 HydrophobicContact CE1-CD2 4.49Å; Y465-L497 HydrophobicContact CE1-CG 4.21Å; Y465-L497 HydrophobicContact CE2-CD2 4.17Å; Y465-L497 HydrophobicContact CG-CD1 3.95Å; Y465-E498 PolarHBondContact OH-N 3.26Å; Y465-E498 PolarHBondContact OH-O 3.43Å; Y465-W499 AromaticContact CD1-CH2 3.67Å; Y465-W499 HydrophobicContact CD1-CH2 3.67Å; Y465-W499 AromaticContact CD1-CZ2 3.85Å; Y465-W499 HydrophobicContact CD1-CZ2 3.85Å; Y465-W499 HydrophobicContact CD1-CZ3 4.25Å; Y465-W499 HydrophobicContact CE1-CD2 4.38Å; Y465-W499 HydrophobicContact CE1-CE3 4.4Å; Y465-W499 AromaticContact CE1-CH2 3.87Å; Y465-W499 HydrophobicContact CE1-CH2 3.87Å; Y465-W499 AromaticContact CE1-CZ2 3.81Å; Y465-W499 HydrophobicContact CE1-CZ2 3.81Å; Y465-W499 HydrophobicContact CE1-CZ3 4.18Å; Y465-V501 HydrophobicContact CD1-CG2 3.69Å; Y465-V501 HydrophobicContact CE1-CB 4.34Å; Y465-V501 HydrophobicContact CE1-CG1 4.21Å; Y465-V501 HydrophobicContact CE1-CG2 3.27Å; Y465-V501 HydrophobicContact CE2-CG1 4.17Å; Y465-F593 HydrophobicContact CD2-CE1 4.44Å; Y465-F593 HydrophobicContact CG-CE1 4.2Å
466G97.3Very high95.1Very high0 Ų028.7 Ų28.70%015%0.145CC..EExtended strand (participates in β ladder)trans-79.6136.8171.800000111F459 V488 C489F459-G466 CarbonylContact O-C 3.58Å; F459-G466 VanDerWaalsContact O-CA 3.31Å; F459-G466 WeakPolarHBondContact O-CA 3.39Å; G466-V488 VanDerWaalsContact O-CG1 3.25Å; G466-V488 WeakPolarHBondContact O-CG1 3.49Å; G466-C489 PolarHBondContact O-N 2.76Å
467F97.6Very high94.1Very high0 Ų035.9 Ų35.90%018%0.178CC..EExtended strand (participates in β ladder)trans-151.8172.717966.7-89.7000112.6T433 R458 F459 N461 F486 H487 V591 F593T433-F467 HydrophobicContact CG2-CE1 4.05Å; T433-F467 HydrophobicContact CG2-CZ 3.72Å; R458-F467 WeakPolarHBondContact CA-O 3.38Å; F459-F467 HydrophobicContact CB-CD1 4.42Å; F459-F467 HydrophobicContact CB-CD2 4.19Å; F459-F467 HydrophobicContact CB-CE1 3.99Å; F459-F467 HydrophobicContact CB-CE2 3.75Å; F459-F467 HydrophobicContact CB-CZ 3.65Å; F459-F467 HydrophobicContact CD2-CD2 4.42Å; F459-F467 HydrophobicContact CD2-CE2 4.12Å; F459-F467 HydrophobicContact CG-CE2 4.33Å; F459-F467 PolarHBondContact N-O 2.7Å; F459-F467 PolarHBondContact O-N 3.48Å; N461-F467 HydrophobicContact CB-CE1 3.91Å; F467-F486 HydrophobicContact CB-CE1 4.47Å; F467-F486 HydrophobicContact CB-CE2 3.75Å; F467-F486 HydrophobicContact CB-CZ 3.57Å; F467-F486 HydrophobicContact CD2-CD2 4.29Å; F467-F486 AromaticContact CD2-CE2 3.42Å; F467-F486 HydrophobicContact CD2-CE2 3.42Å; F467-F486 VanDerWaalsContact CD2-CE2 3.42Å; F467-F486 HydrophobicContact CD2-CZ 4.09Å; F467-F486 HydrophobicContact CE2-CE2 4.2Å; F467-F486 AromaticContact CG-CE2 3.78Å; F467-F486 HydrophobicContact CG-CE2 3.78Å; F467-F486 AromaticContact CG-CZ 3.95Å; F467-F486 HydrophobicContact CG-CZ 3.95Å; F467-H487 CarbonylContact C-O 3.6Å; F467-H487 VanDerWaalsContact CA-O 3.3Å; F467-H487 WeakPolarHBondContact CA-O 3.35Å; F467-H487 WeakPolarHBondContact CB-O 3.42Å; F467-V591 HydrophobicContact CD2-CG1 4.49Å; F467-V591 HydrophobicContact CD2-CG2 4.18Å; F467-V591 HydrophobicContact CE2-CB 4.29Å; F467-V591 HydrophobicContact CE2-CG1 3.71Å; F467-V591 HydrophobicContact CE2-CG2 3.69Å; F467-F593 HydrophobicContact CD1-CB 4.27Å; F467-F593 AromaticContact CD1-CD1 3.85Å; F467-F593 HydrophobicContact CD1-CD1 3.85Å; F467-F593 HydrophobicContact CD1-CG 4.47Å; F467-F593 HydrophobicContact CE1-CB 3.98Å; F467-F593 HydrophobicContact CE1-CD1 4.25Å; F467-F593 HydrophobicContact CE2-CB 4.39Å; F467-F593 HydrophobicContact CG-CD1 4.32Å; F467-F593 HydrophobicContact CZ-CB 4.04Å
468G97.1Very high92.9Very high0 Ų039 Ų390%019%0.19CC..EExtended strand (participates in β ladder)trans-163.5176.4178.400000113S456 H487S456-G468 WeakPolarHBondContact OG-CA 3.49Å; G468-H487 PolarHBondContact N-O 3.05Å; G468-H487 PolarHBondContact O-N 3.31Å
469L97.8Very high91.9Very high0 Ų037.3 Ų37.30%019%0.193CC..EExtended strand (participates in β ladder)trans-113.7147175.9-60.9-177.4000110.9W436 Q455 S456 L484 A485 F486 I508 M589 V591W436-L469 HydrophobicContact CE3-CB 3.97Å; W436-L469 HydrophobicContact CE3-CD1 4.3Å; W436-L469 HydrophobicContact CZ3-CB 4.02Å; Q455-L469 WeakPolarHBondContact CA-O 3.5Å; S456-L469 PolarHBondContact N-O 3.44Å; S456-L469 PolarHBondContact OG-N 3.44Å; L469-L484 HydrophobicContact CB-CD1 4.4Å; L469-A485 CarbonylContact C-O 3.57Å; L469-A485 VanDerWaalsContact CA-O 3.27Å; L469-A485 WeakPolarHBondContact CA-O 3.29Å; L469-F486 HydrophobicContact CD2-CD2 4.32Å; L469-I508 HydrophobicContact CD1-CG2 3.96Å; L469-I508 HydrophobicContact CD2-CD1 3.82Å; L469-I508 HydrophobicContact CD2-CG1 4.14Å; L469-I508 HydrophobicContact CD2-CG2 4.04Å; L469-M589 HydrophobicContact CD1-CB 4.21Å; L469-V591 HydrophobicContact CD1-CB 4.04Å; L469-V591 HydrophobicContact CD1-CG1 4.05Å; L469-V591 HydrophobicContact CD2-CB 4.03Å; L469-V591 HydrophobicContact CD2-CG1 4.4Å; L469-V591 HydrophobicContact CD2-CG2 3.92Å; L469-V591 HydrophobicContact CG-CB 4.16Å; L469-V591 HydrophobicContact CG-CG1 4.05Å; L469-V591 HydrophobicContact CG-CG2 4.49Å
470T96.8Very high91.4Very high0 Ų037.2 Ų37.20%020%0.2CC..EExtended strand (participates in β ladder)trans-118.8119.9167.9-56.30000109.5K453 L454 Q455 Y472 A485 H487 D564K453-T470 HydrophobicContact CB-CG2 3.86Å; K453-T470 HydrophobicContact CD-CG2 3.86Å; K453-T470 HydrophobicContact CG-CG2 4.3Å; L454-T470 CarbonylContact O-C 3.52Å; L454-T470 WeakPolarHBondContact O-CA 3.45Å; Q455-T470 HydrophobicContact CG-CG2 4.27Å; T470-Y472 HydrophobicContact CG2-CD2 4.04Å; T470-Y472 HydrophobicContact CG2-CE2 3.38Å; T470-A485 PolarHBondContact N-O 3.37Å; T470-A485 PolarHBondContact O-N 2.94Å; T470-H487 PolarHBondContact OG1-CE1 3.15Å; T470-H487 PolarHBondContact OG1-ND1 3.32Å; T470-H487 VanDerWaalsContact OG1-ND1 3.14Å; T470-D564 WeakPolarHBondContact CB-OD1 3.34Å; T470-D564 VanDerWaalsContact CB-OD2 3.3Å; T470-D564 WeakPolarHBondContact CB-OD2 3.48Å; T470-D564 VanDerWaalsContact CG2-OD2 3.3Å; T470-D564 WeakPolarHBondContact CG2-OD2 3.22Å; T470-D564 VanDerWaalsContact OG1-CG 3.28Å; T470-D564 PolarHBondContact OG1-OD1 3.39Å; T470-D564 PolarHBondContact OG1-OD2 3.26Å
471L96.4Very high91.2Very high0 Ų038.3 Ų38.30%021%0.205CC..EExtended strand (participates in β ladder)trans-102.1128.9177.617665.7000110.1W436 V438 F441 K453 L454 L482 L484 L587 M589W436-L471 HydrophobicContact CH2-CB 3.61Å; W436-L471 HydrophobicContact CH2-CD2 4.44Å; W436-L471 HydrophobicContact CZ3-CB 3.68Å; V438-L471 HydrophobicContact CG2-CD2 4.3Å; F441-L471 HydrophobicContact CE2-CD2 3.63Å; F441-L471 HydrophobicContact CZ-CD2 4.15Å; K453-L471 CarbonylContact C-O 3.25Å; K453-L471 VanDerWaalsContact CA-O 3.25Å; K453-L471 WeakPolarHBondContact CA-O 3.47Å; L454-L471 HydrophobicContact CB-CB 4.42Å; L454-L471 HydrophobicContact CD1-CD2 4.35Å; L454-L471 HydrophobicContact CD1-CG 4.49Å; L454-L471 PolarHBondContact N-O 3.16Å; L454-L471 PolarHBondContact O-N 3.27Å; L471-L482 HydrophobicContact CD1-CB 4.4Å; L471-L482 HydrophobicContact CD1-CD2 3.91Å; L471-L484 HydrophobicContact CB-CD1 3.96Å; L471-L484 HydrophobicContact CD1-CD1 3.94Å; L471-L587 HydrophobicContact CD2-CD2 3.96Å; L471-M589 HydrophobicContact CD1-SD 4.43Å; L471-M589 HydrophobicContact CD2-CE 4.01Å; L471-M589 HydrophobicContact CD2-SD 4.42Å
472Y95.2Very high91Very high8 Ų837.8 Ų37.83%0.03120%0.202CC..EExtended strand (participates in β ladder)trans-112.8100.2172.4-64.8-98.3000108.2D34 K453 T470 H474 G475 R483 D564D34-Y472 PolarHBondContact OD2-OH 2.75Å; K453-Y472 HydrophobicContact CB-CD1 3.8Å; K453-Y472 HydrophobicContact CB-CE1 3.64Å; K453-Y472 HydrophobicContact CB-CG 4.29Å; K453-Y472 HydrophobicContact CD-CE1 3.88Å; K453-Y472 WeakPolarHBondContact CD-OH 3.37Å; K453-Y472 HydrophobicContact CG-CE1 4.33Å; T470-Y472 HydrophobicContact CG2-CD2 4.04Å; T470-Y472 HydrophobicContact CG2-CE2 3.38Å; Y472-H474 VanDerWaalsContact C-N 3.28Å; Y472-H474 PolarHBondContact O-N 2.75Å; Y472-G475 PolarHBondContact O-N 3.38Å; Y472-R483 HydrophobicContact CD2-CB 4.31Å; Y472-R483 HydrophobicContact CD2-CG 3.76Å; Y472-R483 HydrophobicContact CG-CB 4.45Å; Y472-R483 HydrophobicContact CG-CG 4.32Å; Y472-R483 PolarHBondContact N-O 2.96Å; Y472-R483 PolarHBondContact O-N 3.2Å; Y472-R483 VanDerWaalsContact O-N 3.09Å; Y472-D564 PolarHBondContact OH-OD2 3.2Å
473P94.8Very high91Very high0 Ų033.1 Ų33.10%017%0.169CC..THydrogen-bonded Turntrans-59.8-35.2-171-26.135.3000114F441 V444 L445 T448 D452 L454 H573F441-P473 HydrophobicContact CZ-CB 4.27Å; V444-P473 HydrophobicContact CG1-CB 4.44Å; V444-P473 HydrophobicContact CG1-CG 3.82Å; L445-P473 HydrophobicContact CD2-CB 3.8Å; T448-P473 HydrophobicContact CG2-CG 4.31Å; D452-P473 WeakPolarHBondContact O-CD 3.43Å; L454-P473 HydrophobicContact CD1-CG 3.26Å; P473-H573 PolarHBondContact O-NE2 3.48Å
474H92.3Very high91Very high39 Ų3929.9 Ų29.918%0.18115%0.154CC..THydrogen-bonded Turntrans-107.316.2177.3-68.1-76.3000113.3L445 T448 Y472 E477 Y481 H573L445-H474 PolarHBondContact O-CE1 2.67Å; L445-H474 PolarHBondContact O-NE2 3.17Å; T448-H474 PolarHBondContact O-CD2 3.22Å; T448-H474 PolarHBondContact O-NE2 2.96Å; T448-H474 VanDerWaalsContact O-NE2 3.1Å; T448-H474 PolarHBondContact OG1-CD2 3.26Å; Y472-H474 VanDerWaalsContact C-N 3.28Å; Y472-H474 PolarHBondContact O-N 2.75Å; H474-E477 VanDerWaalsContact O-O 3.08Å; H474-Y481 CarbonylContact C-O 3.58Å; H474-H573 AromaticContact ND1-CE1 3.44Å; H474-H573 PolarHBondContact ND1-CE1 2.74Å
475G89.3Confident90.9Very high1 Ų129.4 Ų29.41%0.0115%0.149CC..THydrogen-bonded Turntrans60.9-166.1-170.100000112.8G451 Y472 Y481G451-G475 PolarHBondContact N-O 3.26Å; Y472-G475 PolarHBondContact O-N 3.38Å; G475-Y481 PolarHBondContact N-O 3.45Å
476R82.8Confident90.9Very high74 Ų7429.2 Ų29.228%0.27915%0.149SC..THydrogen-bonded Turntrans-90.3-29.9173-66.1-160-169.2110.325.7113.2D34 D36 R483D34-R476 IonicContact OD2-CZ 3.87Å; D34-R476 VanDerWaalsContact OD2-CZ 3.23Å; D34-R476 IonicContact OD2-NE 3.69Å; D34-R476 PolarHBondContact OD2-NE 3.49Å; D34-R476 IonicContact OD2-NH2 2.62Å; D34-R476 PolarHBondContact OD2-NH2 3.27Å; D36-R476 VanDerWaalsContact CG-NH1 3.34Å; D36-R476 IonicContact OD1-CZ 2.93Å; D36-R476 IonicContact OD1-NH1 3.66Å; D36-R476 PolarHBondContact OD1-NH1 3.45Å; D36-R476 IonicContact OD1-NH2 3.97Å; D36-R476 PolarHBondContact OD1-NH2 2.9Å; D36-R476 IonicContact OD2-NH1 3.49Å; D36-R476 PolarHBondContact OD2-NH1 2.95Å; D36-R476 VanDerWaalsContact OD2-NH1 3.09Å; R476-R483 VanDerWaalsContact NH2-NH2 3.13Å
477E76.7Confident90.9Very high157 Ų15729.3 Ų29.373%0.73415%0.149SC*.THydrogen-bonded Turntrans-116.3157.7177.4-59.4-169.7170.900108.4H474 S479H474-E477 VanDerWaalsContact O-O 3.08Å; E477-S479 PolarHBondContact O-N 3.37Å
478N67.9Low90.9Very high144 Ų14429.3 Ų29.377%0.7715%0.149SC*.THydrogen-bonded Turntrans-74.978.1-178.6-165.331.9000110
479S74.1Confident90.9Very high59 Ų5929.4 Ų29.441%0.41315%0.149SC..SBendtrans-100.8-19.3-174.261.40000112.9E477 Y481E477-S479 PolarHBondContact O-N 3.37Å; S479-Y481 WeakPolarHBondContact O-CD2 3.33Å; S479-Y481 PolarHBondContact OG-N 3.01Å
480G87.3Confident90.8Very high29 Ų2930.2 Ų30.230%0.29916%0.155SC..SBendtrans74.417.6-168.700000113.2H573G480-H573 PolarHBondContact O-N 3.15Å
481Y91.1Very high90.7Very high103 Ų10331 Ų3140%0.40416%0.164SC..EExtended strand (participates in β ladder)trans-119.7153.5176.7-68.7-102000111.2H474 G475 S479 I571 S572H474-Y481 CarbonylContact C-O 3.58Å; G475-Y481 PolarHBondContact N-O 3.45Å; S479-Y481 WeakPolarHBondContact O-CD2 3.33Å; S479-Y481 PolarHBondContact OG-N 3.01Å; Y481-I571 WeakPolarHBondContact CA-O 3.21Å; Y481-S572 VanDerWaalsContact CE1-CB 3.46Å
482L93Very high90.6Very high0 Ų039 Ų390%020%0.201CC..EExtended strand (participates in β ladder)trans-82.2142.7163.2-61.194.8000109.3F441 L471 F570 I571 L576 L587F441-L482 HydrophobicContact CE1-CD2 3.74Å; F441-L482 HydrophobicContact CZ-CD2 3.42Å; F441-L482 VanDerWaalsContact CZ-CD2 3.42Å; L471-L482 HydrophobicContact CD1-CB 4.4Å; L471-L482 HydrophobicContact CD1-CD2 3.91Å; L482-F570 WeakPolarHBondContact O-CB 3.18Å; L482-F570 PolarHBondContact O-N 2.84Å; L482-I571 HydrophobicContact CB-CG2 4.32Å; L482-I571 HydrophobicContact CD1-CG2 3.62Å; L482-I571 WeakPolarHBondContact CD1-O 3.31Å; L482-I571 HydrophobicContact CG-CG2 4.49Å; L482-I571 PolarHBondContact N-O 3.29Å; L482-L576 HydrophobicContact CD1-CD1 3.24Å; L482-L576 HydrophobicContact CD1-CD2 4.37Å; L482-L576 HydrophobicContact CD1-CG 3.69Å; L482-L576 HydrophobicContact CD2-CD1 3.93Å; L482-L576 HydrophobicContact CG-CD1 4.22Å; L482-L587 HydrophobicContact CD2-CD2 4.45Å
483R93.3Very high90.6Very high0 Ų041 Ų410%021%0.212CC..EExtended strand (participates in β ladder)trans-105.2138.2165.1161.2176.4-176.984.51.9109.6A35 D36 Y472 R476 G566 W567 S568A35-R483 PolarHBondContact O-NH2 3.21Å; A35-R483 VanDerWaalsContact O-NH2 3.16Å; D36-R483 IonicContact OD1-CZ 3.11Å; D36-R483 IonicContact OD1-NE 3.46Å; D36-R483 IonicContact OD1-NH1 2.99Å; D36-R483 PolarHBondContact OD1-NH1 2.89Å; D36-R483 IonicContact OD1-NH2 2.8Å; D36-R483 PolarHBondContact OD1-NH2 3.38Å; D36-R483 IonicContact OD2-CZ 2.83Å; D36-R483 IonicContact OD2-NH1 2.7Å; D36-R483 PolarHBondContact OD2-NH1 3.44Å; Y472-R483 HydrophobicContact CD2-CB 4.31Å; Y472-R483 HydrophobicContact CD2-CG 3.76Å; Y472-R483 HydrophobicContact CG-CB 4.45Å; Y472-R483 HydrophobicContact CG-CG 4.32Å; Y472-R483 PolarHBondContact N-O 2.96Å; Y472-R483 PolarHBondContact O-N 3.2Å; Y472-R483 VanDerWaalsContact O-N 3.09Å; R476-R483 VanDerWaalsContact NH2-NH2 3.13Å; R483-G566 PolarHBondContact NH1-O 3.31Å; R483-G566 VanDerWaalsContact NH1-O 3.08Å; R483-W567 WeakPolarHBondContact CA-O 3.42Å; R483-W567 WeakPolarHBondContact CB-O 3.28Å; R483-W567 VanDerWaalsContact CG-O 3.31Å; R483-W567 WeakPolarHBondContact CG-O 3.18Å; R483-S568 PolarHBondContact NH1-OG 3.25Å
484L95.3Very high90.7Very high0 Ų041.2 Ų41.20%021%0.213CC..EExtended strand (participates in β ladder)trans-130.1134.9174.4-16459.7000109.3L469 L471 I508 I510 W567 F570 M589L469-L484 HydrophobicContact CB-CD1 4.4Å; L471-L484 HydrophobicContact CB-CD1 3.96Å; L471-L484 HydrophobicContact CD1-CD1 3.94Å; L484-I508 HydrophobicContact CD2-CB 4.47Å; L484-I508 HydrophobicContact CD2-CG2 3.27Å; L484-I508 HydrophobicContact CG-CG2 3.98Å; L484-I510 HydrophobicContact CD2-CD1 4.5Å; L484-I510 HydrophobicContact CD2-CG1 4.23Å; L484-W567 PolarHBondContact N-O 2.96Å; L484-W567 PolarHBondContact O-N 3.19Å; L484-F570 HydrophobicContact CB-CB 4.29Å; L484-F570 HydrophobicContact CB-CD2 3.67Å; L484-F570 HydrophobicContact CB-CE2 4.13Å; L484-F570 HydrophobicContact CB-CG 3.99Å; L484-F570 HydrophobicContact CD2-CD2 4.29Å; L484-F570 HydrophobicContact CD2-CE1 4.39Å; L484-F570 HydrophobicContact CD2-CE2 3.99Å; L484-F570 HydrophobicContact CD2-CZ 4.06Å; L484-M589 HydrophobicContact CD1-SD 3.62Å; L484-M589 HydrophobicContact CD2-CG 4.29Å; L484-M589 HydrophobicContact CD2-SD 3.84Å; L484-M589 HydrophobicContact CG-SD 4.43Å
485A95.9Very high90.8Very high0 Ų043.1 Ų43.10%024%0.236CC..EExtended strand (participates in β ladder)trans-137.2154.9-177.100000111.8L469 T470 D564 F565L469-A485 CarbonylContact C-O 3.57Å; L469-A485 VanDerWaalsContact CA-O 3.27Å; L469-A485 WeakPolarHBondContact CA-O 3.29Å; T470-A485 PolarHBondContact N-O 3.37Å; T470-A485 PolarHBondContact O-N 2.94Å; A485-D564 HydrophobicContact CB-CB 3.75Å; A485-F565 WeakPolarHBondContact CA-O 3.38Å
486F97.7Very high91.1Very high0 Ų050.1 Ų50.10%027%0.272CS..EExtended strand (participates in β ladder)trans-107.2144.7177.3177.6-89.6000110.3F467 L469 V488 V506 I508 F527 W544 F565 V591 F593F467-F486 HydrophobicContact CB-CE1 4.47Å; F467-F486 HydrophobicContact CB-CE2 3.75Å; F467-F486 HydrophobicContact CB-CZ 3.57Å; F467-F486 HydrophobicContact CD2-CD2 4.29Å; F467-F486 AromaticContact CD2-CE2 3.42Å; F467-F486 HydrophobicContact CD2-CE2 3.42Å; F467-F486 VanDerWaalsContact CD2-CE2 3.42Å; F467-F486 HydrophobicContact CD2-CZ 4.09Å; F467-F486 HydrophobicContact CE2-CE2 4.2Å; F467-F486 AromaticContact CG-CE2 3.78Å; F467-F486 HydrophobicContact CG-CE2 3.78Å; F467-F486 AromaticContact CG-CZ 3.95Å; F467-F486 HydrophobicContact CG-CZ 3.95Å; L469-F486 HydrophobicContact CD2-CD2 4.32Å; F486-V488 HydrophobicContact CE1-CG2 3.76Å; F486-V488 HydrophobicContact CZ-CG2 4.39Å; F486-V506 HydrophobicContact CB-CG1 4.17Å; F486-V506 HydrophobicContact CD1-CG2 4.05Å; F486-V506 HydrophobicContact CD2-CG1 3.55Å; F486-V506 HydrophobicContact CD2-CG2 4.12Å; F486-V506 HydrophobicContact CE1-CG2 3.89Å; F486-V506 HydrophobicContact CE2-CG1 3.99Å; F486-V506 HydrophobicContact CE2-CG2 3.94Å; F486-V506 HydrophobicContact CG-CG1 3.87Å; F486-V506 HydrophobicContact CG-CG2 4.16Å; F486-V506 HydrophobicContact CZ-CG2 3.83Å; F486-I508 HydrophobicContact CB-CD1 4.06Å; F486-F527 HydrophobicContact CB-CE1 4.08Å; F486-F527 HydrophobicContact CB-CZ 4.03Å; F486-F527 AromaticContact CD1-CZ 3.96Å; F486-F527 HydrophobicContact CD1-CZ 3.96Å; F486-F527 HydrophobicContact CG-CZ 4.17Å; F486-W544 AromaticContact CD1-CH2 3.94Å; F486-W544 HydrophobicContact CD1-CH2 3.94Å; F486-W544 AromaticContact CD1-CZ3 3.77Å; F486-W544 HydrophobicContact CD1-CZ3 3.77Å; F486-W544 HydrophobicContact CE1-CH2 4.46Å; F486-W544 AromaticContact CE1-CZ3 3.97Å; F486-W544 HydrophobicContact CE1-CZ3 3.97Å; F486-F565 PolarHBondContact N-O 3.29Å; F486-F565 PolarHBondContact O-N 3.04Å; F486-V591 HydrophobicContact CD2-CG2 4.01Å; F486-V591 HydrophobicContact CE2-CG2 4.11Å; F486-F593 HydrophobicContact CE1-CE2 4.34Å; F486-F593 HydrophobicContact CE1-CZ 4.49Å; F486-F593 HydrophobicContact CE2-CB 4.38Å; F486-F593 HydrophobicContact CE2-CD2 4.47Å; F486-F593 HydrophobicContact CE2-CG 4.32Å; F486-F593 HydrophobicContact CZ-CB 4.42Å; F486-F593 HydrophobicContact CZ-CD1 4.06Å; F486-F593 AromaticContact CZ-CD2 3.88Å; F486-F593 HydrophobicContact CZ-CD2 3.88Å; F486-F593 HydrophobicContact CZ-CE1 4.23Å; F486-F593 HydrophobicContact CZ-CE2 4.02Å; F486-F593 AromaticContact CZ-CG 3.87Å; F486-F593 HydrophobicContact CZ-CG 3.87Å; F486-F593 HydrophobicContact CZ-CZ 4.2Å
487H96.9Very high91.8Very high1 Ų148 Ų481%0.00527%0.265CS..EExtended strand (participates in β ladder)trans-141.4152.2170.658.2-100.2000111.3F467 G468 T470 C489 R561 S562 D564F467-H487 CarbonylContact C-O 3.6Å; F467-H487 VanDerWaalsContact CA-O 3.3Å; F467-H487 WeakPolarHBondContact CA-O 3.35Å; F467-H487 WeakPolarHBondContact CB-O 3.42Å; G468-H487 PolarHBondContact N-O 3.05Å; G468-H487 PolarHBondContact O-N 3.31Å; T470-H487 PolarHBondContact OG1-CE1 3.15Å; T470-H487 PolarHBondContact OG1-ND1 3.32Å; T470-H487 VanDerWaalsContact OG1-ND1 3.14Å; H487-C489 PolarHBondContact CD2-SG 3.04Å; H487-R561 PolarHBondContact NE2-NE 2.74Å; H487-S562 WeakPolarHBondContact CA-OG 3.35Å; H487-D564 IonicContact CG-OD1 3.34Å; H487-D564 IonicContact ND1-OD1 3.3Å; H487-D564 PolarHBondContact ND1-OD1 3.21Å; H487-D564 VanDerWaalsContact ND1-OD1 3.13Å
488V97.3Very high92.8Very high0 Ų046.7 Ų46.70%026%0.259CS..EExtended strand (participates in β ladder)trans-94.2138.3171.5-174.60000108.7G466 F486 W499 W544 P547 R561 S562G466-V488 VanDerWaalsContact O-CG1 3.25Å; G466-V488 WeakPolarHBondContact O-CG1 3.49Å; F486-V488 HydrophobicContact CE1-CG2 3.76Å; F486-V488 HydrophobicContact CZ-CG2 4.39Å; V488-W499 HydrophobicContact CG1-CH2 3.66Å; V488-W499 HydrophobicContact CG1-CZ3 3.9Å; V488-W544 HydrophobicContact CG2-CE3 3.88Å; V488-W544 HydrophobicContact CG2-CZ3 4.12Å; V488-P547 HydrophobicContact CB-CG 4.15Å; V488-P547 HydrophobicContact CG1-CG 3.86Å; V488-R561 WeakPolarHBondContact O-CA 3.23Å; V488-S562 PolarHBondContact N-OG 3.27Å; V488-S562 PolarHBondContact O-N 3.34Å
489C96.5Very high94.1Very high2 Ų242 Ų421%0.01423%0.231CC..EExtended strand (participates in β ladder)trans-109.6143.4-179.3-65.20000110.3R458 G466 H487 G491 F560R458-C489 HydrophobicContact CG-CB 3.99Å; G466-C489 PolarHBondContact O-N 2.76Å; H487-C489 PolarHBondContact CD2-SG 3.04Å; C489-G491 PolarHBondContact O-N 3.08Å; C489-F560 CarbonylContact C-O 3.31Å; C489-F560 VanDerWaalsContact CA-O 3.32Å; C489-F560 WeakPolarHBondContact CA-O 3.19Å
490S97.4Very high95.2Very high18 Ų1840.3 Ų40.313%0.12622%0.219CC..  trans-64.8134.3169.565.40000110.3R458 D494 F560R458-S490 PolarHBondContact NH1-O 3.26Å; S490-D494 WeakPolarHBondContact CA-OD2 3.32Å; S490-D494 WeakPolarHBondContact CB-OD2 3.4Å; S490-F560 PolarHBondContact N-O 3.03Å; S490-F560 PolarHBondContact OG-N 3.23Å
491G94.1Very high95.7Very high17 Ų1739 Ų3918%0.17521%0.205CC..  trans-133.1178.8178.100000113C489 N493 D494C489-G491 PolarHBondContact O-N 3.08Å; G491-N493 PolarHBondContact O-N 3.49Å; G491-D494 VanDerWaalsContact N-CG 3.25Å; G491-D494 PolarHBondContact N-OD1 2.7Å; G491-D494 PolarHBondContact N-OD2 3.13Å; G491-D494 VanDerWaalsContact O-CG 3.26Å; G491-D494 PolarHBondContact O-N 3.21Å
492E93.4Very high95.9Very high168 Ų16836.1 Ų36.179%0.78520%0.195SC*.THydrogen-bonded Turntrans-66.4-24.7178.762.4-172.116700113.2
493N95.9Very high96.1Very high50 Ų5038.6 Ų38.627%0.26721%0.208SC..THydrogen-bonded Turntrans-85.2-12.4-177.1-56.7-43.6000113.4G464 G491 A495 I496 L497G464-N493 PolarHBondContact O-ND2 3.24Å; G464-N493 VanDerWaalsContact O-ND2 3.11Å; G491-N493 PolarHBondContact O-N 3.49Å; N493-A495 PolarHBondContact O-N 2.8Å; N493-I496 WeakPolarHBondContact O-CG1 3.34Å; N493-I496 PolarHBondContact O-N 2.89Å; N493-L497 HydrophobicContact CB-CD1 3.85Å; N493-L497 HydrophobicContact CB-CG 4.19Å; N493-L497 WeakPolarHBondContact O-CG 3.42Å; N493-L497 PolarHBondContact O-N 2.66Å
494D96.3Very high96.3Very high3 Ų339.6 Ų39.62%0.01621%0.212CC..THydrogen-bonded Turntrans-55-25.2-170.1-71.812.5000114.8S490 G491 I496 W499 R546S490-D494 WeakPolarHBondContact CA-OD2 3.32Å; S490-D494 WeakPolarHBondContact CB-OD2 3.4Å; G491-D494 VanDerWaalsContact N-CG 3.25Å; G491-D494 PolarHBondContact N-OD1 2.7Å; G491-D494 PolarHBondContact N-OD2 3.13Å; G491-D494 VanDerWaalsContact O-CG 3.26Å; G491-D494 PolarHBondContact O-N 3.21Å; D494-I496 VanDerWaalsContact C-N 3.32Å; D494-W499 HydrophobicContact CB-CZ2 4.34Å; D494-W499 PolarHBondContact O-NE1 3.19Å; D494-W499 VanDerWaalsContact O-NE1 3.09Å; D494-R546 IonicContact OD2-NE 2.67Å
495A95Very high96.4Very high80 Ų8040.3 Ų40.366%0.66122%0.215SC*.THydrogen-bonded Turntrans-71.5-24-178.800000113.8N493N493-A495 PolarHBondContact O-N 2.8Å
496I96.1Very high96.5Very high148 Ų14840.3 Ų40.376%0.75922%0.215SC*.THydrogen-bonded Turntrans-106.9-16.2-179.561.9162.8000113.2N493 D494N493-I496 WeakPolarHBondContact O-CG1 3.34Å; N493-I496 PolarHBondContact O-N 2.89Å; D494-I496 VanDerWaalsContact C-N 3.32Å
497L97.3Very high96.5Very high28 Ų2841.2 Ų41.215%0.14722%0.22CC..SBendtrans-74.7153.4-179.5-65.3173.8000112E463 Y465 N493E463-L497 WeakPolarHBondContact O-CD2 3.33Å; Y465-L497 HydrophobicContact CD1-CB 4.41Å; Y465-L497 HydrophobicContact CD1-CD1 3.63Å; Y465-L497 HydrophobicContact CD1-CG 4.49Å; Y465-L497 HydrophobicContact CD2-CD1 4.43Å; Y465-L497 HydrophobicContact CD2-CD2 4.48Å; Y465-L497 HydrophobicContact CE1-CB 3.72Å; Y465-L497 HydrophobicContact CE1-CD1 3.82Å; Y465-L497 HydrophobicContact CE1-CD2 4.49Å; Y465-L497 HydrophobicContact CE1-CG 4.21Å; Y465-L497 HydrophobicContact CE2-CD2 4.17Å; Y465-L497 HydrophobicContact CG-CD1 3.95Å; N493-L497 HydrophobicContact CB-CD1 3.85Å; N493-L497 HydrophobicContact CB-CG 4.19Å; N493-L497 WeakPolarHBondContact O-CG 3.42Å; N493-L497 PolarHBondContact O-N 2.66Å
498E96.8Very high96.6Very high130 Ų13041.1 Ų41.161%0.60722%0.22SC*.  trans-79138.5176-172.3173.4-174.900110.8Y465Y465-E498 PolarHBondContact OH-N 3.26Å; Y465-E498 PolarHBondContact OH-O 3.43Å
499W96.7Very high96.6Very high46 Ų4641.6 Ų41.617%0.17422%0.222CC..SBendtrans-138.7141.7177.9-60.696000110.3Y465 V488 D494 V501 D545 R546 P547Y465-W499 AromaticContact CD1-CH2 3.67Å; Y465-W499 HydrophobicContact CD1-CH2 3.67Å; Y465-W499 AromaticContact CD1-CZ2 3.85Å; Y465-W499 HydrophobicContact CD1-CZ2 3.85Å; Y465-W499 HydrophobicContact CD1-CZ3 4.25Å; Y465-W499 HydrophobicContact CE1-CD2 4.38Å; Y465-W499 HydrophobicContact CE1-CE3 4.4Å; Y465-W499 AromaticContact CE1-CH2 3.87Å; Y465-W499 HydrophobicContact CE1-CH2 3.87Å; Y465-W499 AromaticContact CE1-CZ2 3.81Å; Y465-W499 HydrophobicContact CE1-CZ2 3.81Å; Y465-W499 HydrophobicContact CE1-CZ3 4.18Å; V488-W499 HydrophobicContact CG1-CH2 3.66Å; V488-W499 HydrophobicContact CG1-CZ3 3.9Å; D494-W499 HydrophobicContact CB-CZ2 4.34Å; D494-W499 PolarHBondContact O-NE1 3.19Å; D494-W499 VanDerWaalsContact O-NE1 3.09Å; W499-V501 HydrophobicContact CD2-CG2 4.32Å; W499-V501 HydrophobicContact CE3-CG2 3.44Å; W499-V501 VanDerWaalsContact CE3-CG2 3.44Å; W499-V501 HydrophobicContact CH2-CG2 4.07Å; W499-V501 HydrophobicContact CZ3-CG2 3.29Å; W499-D545 VanDerWaalsContact CE3-C 3.47Å; W499-R546 HydrophobicContact CB-CB 4.43Å; W499-R546 HydrophobicContact CD2-CB 3.79Å; W499-R546 HydrophobicContact CD2-CG 4.25Å; W499-R546 VanDerWaalsContact CE3-CA 3.49Å; W499-R546 HydrophobicContact CE3-CB 4.22Å; W499-R546 HydrophobicContact CG-CB 3.86Å; W499-R546 HydrophobicContact CG-CG 4.47Å; W499-R546 HydrophobicContact CZ2-CG 4.34Å; W499-P547 VanDerWaalsContact CH2-CD 3.41Å; W499-P547 HydrophobicContact CH2-CG 4.22Å; W499-P547 HydrophobicContact CZ3-CG 4.46Å
500P96.6Very high96.7Very high24 Ų2441.5 Ų41.516%0.15622%0.222CC..SBendcis-69.2154.1-3.630.9-35.9000112.5E502 K531 V542 W544 D545P500-E502 PolarHBondContact O-N 3.34Å; P500-K531 HydrophobicContact CG-CD 4.32Å; P500-K531 HydrophobicContact CG-CG 3.79Å; P500-V542 HydrophobicContact CB-CB 4.37Å; P500-V542 HydrophobicContact CB-CG1 3.78Å; P500-V542 HydrophobicContact CG-CG1 4.3Å; P500-W544 CarbonylContact C-O 3.53Å; P500-W544 WeakPolarHBondContact CA-O 3.48Å; P500-W544 HydrophobicContact CB-CB 4.5Å; P500-W544 WeakPolarHBondContact CB-O 3.4Å; P500-D545 HydrophobicContact CB-CB 4.39Å
501V96.7Very high96.8Very high1 Ų140.8 Ų40.81%0.00622%0.216CC..  trans-72.7115.5178.3-164.70000109.2Y465 W499 R504 T529 W544 F593Y465-V501 HydrophobicContact CD1-CG2 3.69Å; Y465-V501 HydrophobicContact CE1-CB 4.34Å; Y465-V501 HydrophobicContact CE1-CG1 4.21Å; Y465-V501 HydrophobicContact CE1-CG2 3.27Å; Y465-V501 HydrophobicContact CE2-CG1 4.17Å; W499-V501 HydrophobicContact CD2-CG2 4.32Å; W499-V501 HydrophobicContact CE3-CG2 3.44Å; W499-V501 VanDerWaalsContact CE3-CG2 3.44Å; W499-V501 HydrophobicContact CH2-CG2 4.07Å; W499-V501 HydrophobicContact CZ3-CG2 3.29Å; V501-R504 HydrophobicContact CG1-CB 4.31Å; V501-R504 HydrophobicContact CG1-CG 4.06Å; V501-T529 WeakPolarHBondContact O-CB 3.01Å; V501-T529 PolarHBondContact O-OG1 3.15Å; V501-W544 HydrophobicContact CB-CB 4.32Å; V501-W544 PolarHBondContact N-O 3.32Å; V501-W544 WeakPolarHBondContact O-CB 3.48Å; V501-F593 HydrophobicContact CG1-CZ 3.8Å
502E96.1Very high96.9Very high43 Ų4340 Ų4020%0.20121%0.208CC..  trans-117.9155.6179.7-68.2-175.7-91.200111.1P500 R504 T529 K531P500-E502 PolarHBondContact O-N 3.34Å; E502-R504 WeakPolarHBondContact O-CD 2.97Å; E502-R504 PolarHBondContact O-N 3.03Å; E502-R504 VanDerWaalsContact O-N 3.08Å; E502-R504 PolarHBondContact O-NH1 2.8Å; E502-T529 VanDerWaalsContact C-OG1 3.32Å; E502-T529 WeakPolarHBondContact CA-OG1 3.24Å; E502-K531 HydrophobicContact CG-CD 4.5Å; E502-K531 HydrophobicContact CG-CG 4.04Å; E502-K531 WeakPolarHBondContact OE1-CE 3.35Å; E502-K531 IonicContact OE1-NZ 2.6Å; E502-K531 PolarHBondContact OE1-NZ 2.95Å; E502-K531 WeakPolarHBondContact OE2-CD 3.32Å; E502-K531 VanDerWaalsContact OE2-CG 3.28Å; E502-K531 WeakPolarHBondContact OE2-CG 3.49Å; E502-K531 IonicContact OE2-NZ 3.62Å
503N96.9Very high97.1Very high51 Ų5132 Ų3227%0.27317%0.171SC..SBendtrans61.817.6169.8-54.2-26.7000115.1L89 T529 I596 T597L89-N503 HydrophobicContact CD2-CB 3.58Å; L89-N503 WeakPolarHBondContact CD2-OD1 3.25Å; N503-T529 PolarHBondContact N-O 3.03Å; N503-T529 PolarHBondContact N-OG1 3.08Å; N503-I596 WeakPolarHBondContact O-CG1 3.35Å; N503-I596 PolarHBondContact O-N 2.87Å; N503-T597 WeakPolarHBondContact CB-OG1 3.3Å; N503-T597 PolarHBondContact ND2-OG1 2.91Å
504R97.8Very high97Very high22 Ų2232.3 Ų32.38%0.08317%0.171CC..EExtended strand (participates in β ladder)trans-94.5125170.4-80.559.7175.8-174.54.2108.3E463 V501 E502 T528 T529 F593 E594 D595E463-R504 IonicContact OE1-CZ 3.38Å; E463-R504 IonicContact OE1-NE 2.75Å; E463-R504 IonicContact OE1-NH2 3.45Å; E463-R504 PolarHBondContact OE1-NH2 2.91Å; E463-R504 IonicContact OE2-CZ 3.5Å; E463-R504 IonicContact OE2-NE 3.53Å; E463-R504 PolarHBondContact OE2-NE 2.97Å; E463-R504 IonicContact OE2-NH2 3.49Å; V501-R504 HydrophobicContact CG1-CB 4.31Å; V501-R504 HydrophobicContact CG1-CG 4.06Å; E502-R504 WeakPolarHBondContact O-CD 2.97Å; E502-R504 PolarHBondContact O-N 3.03Å; E502-R504 VanDerWaalsContact O-N 3.08Å; E502-R504 PolarHBondContact O-NH1 2.8Å; R504-T528 WeakPolarHBondContact O-CA 3.48Å; R504-T529 PolarHBondContact N-OG1 3.19Å; R504-T529 PolarHBondContact O-N 3.24Å; R504-F593 HydrophobicContact CB-CD2 3.7Å; R504-F593 HydrophobicContact CB-CE2 3.2Å; R504-F593 HydrophobicContact CB-CZ 3.73Å; R504-F593 HydrophobicContact CG-CE2 4.06Å; R504-F593 HydrophobicContact CG-CZ 4.15Å; R504-E594 CarbonylContact C-O 3.54Å; R504-E594 VanDerWaalsContact CA-O 3.23Å; R504-E594 WeakPolarHBondContact CA-O 3.34Å; R504-D595 HydrophobicContact CG-CB 4.39Å
505Q97.9Very high96.9Very high14 Ų1432.8 Ų32.87%0.06517%0.174CC..EExtended strand (participates in β ladder)trans-85.2128.1177.5-173.716466.600109.5N90 I507 V526 F527 F593 E594 I596N90-Q505 PolarHBondContact O-NE2 3.09Å; N90-Q505 VanDerWaalsContact O-NE2 3.13Å; N90-Q505 PolarHBondContact OD1-NE2 2.72Å; Q505-I507 HydrophobicContact CG-CG1 4.24Å; Q505-V526 VanDerWaalsContact CD-CG1 3.41Å; Q505-V526 HydrophobicContact CG-CG1 3.5Å; Q505-F527 CarbonylContact C-O 3.59Å; Q505-F527 WeakPolarHBondContact CA-O 3.32Å; Q505-F593 WeakPolarHBondContact O-CA 3.02Å; Q505-E594 PolarHBondContact N-O 3.43Å; Q505-E594 PolarHBondContact O-N 3.11Å; Q505-E594 VanDerWaalsContact O-N 3.08Å; Q505-I596 HydrophobicContact CB-CD1 3.76Å; Q505-I596 HydrophobicContact CB-CG1 4.01Å; Q505-I596 HydrophobicContact CB-CG2 4.04Å; Q505-I596 HydrophobicContact CG-CD1 4.42Å
506V98.3Very high96.8Very high0 Ų030 Ų300%015%0.148CC..EExtended strand (participates in β ladder)trans-100123.9172.1179.10000107.9F486 I508 V526 F527 V591 D592 F593F486-V506 HydrophobicContact CB-CG1 4.17Å; F486-V506 HydrophobicContact CD1-CG2 4.05Å; F486-V506 HydrophobicContact CD2-CG1 3.55Å; F486-V506 HydrophobicContact CD2-CG2 4.12Å; F486-V506 HydrophobicContact CE1-CG2 3.89Å; F486-V506 HydrophobicContact CE2-CG1 3.99Å; F486-V506 HydrophobicContact CE2-CG2 3.94Å; F486-V506 HydrophobicContact CG-CG1 3.87Å; F486-V506 HydrophobicContact CG-CG2 4.16Å; F486-V506 HydrophobicContact CZ-CG2 3.83Å; V506-I508 HydrophobicContact CG1-CD1 4.28Å; V506-I508 HydrophobicContact CG1-CG1 3.77Å; V506-V526 WeakPolarHBondContact O-CA 3.28Å; V506-F527 HydrophobicContact CB-CD1 4Å; V506-F527 HydrophobicContact CB-CE1 3.61Å; V506-F527 HydrophobicContact CB-CE2 4.13Å; V506-F527 HydrophobicContact CB-CG 4.44Å; V506-F527 HydrophobicContact CB-CZ 3.67Å; V506-F527 HydrophobicContact CG1-CD1 4.33Å; V506-F527 HydrophobicContact CG1-CE1 3.67Å; V506-F527 HydrophobicContact CG1-CZ 3.99Å; V506-F527 HydrophobicContact CG2-CE1 4.04Å; V506-F527 HydrophobicContact CG2-CE2 3.84Å; V506-F527 HydrophobicContact CG2-CZ 3.54Å; V506-F527 PolarHBondContact N-O 3.01Å; V506-F527 PolarHBondContact O-N 2.9Å; V506-V591 HydrophobicContact CG1-CG2 4.44Å; V506-D592 VanDerWaalsContact CA-O 3.29Å; V506-D592 WeakPolarHBondContact CA-O 3.05Å; V506-F593 HydrophobicContact CG2-CD2 3.44Å; V506-F593 VanDerWaalsContact CG2-CD2 3.44Å; V506-F593 HydrophobicContact CG2-CE2 3.78Å; V506-F593 HydrophobicContact CG2-CG 4.44Å
507I97.9Very high96.7Very high19 Ų1923.6 Ų23.610%0.09712%0.116CC..EExtended strand (participates in β ladder)trans-116.6118.3170.8-55.3175.7000106.7Y97 Q505 V526 V591 D592Y97-I507 HydrophobicContact CD1-CD1 4.43Å; Y97-I507 HydrophobicContact CD2-CD1 4.27Å; Y97-I507 HydrophobicContact CE1-CG2 3.99Å; Y97-I507 HydrophobicContact CG-CD1 4.2Å; Q505-I507 HydrophobicContact CG-CG1 4.24Å; I507-V526 HydrophobicContact CB-CG2 4.44Å; I507-V526 HydrophobicContact CG1-CG1 4.03Å; I507-V526 HydrophobicContact CG1-CG2 4.02Å; I507-V526 HydrophobicContact CG2-CG2 4.13Å; I507-V591 CarbonylContact O-C 3.57Å; I507-V591 VanDerWaalsContact O-CA 3.29Å; I507-V591 WeakPolarHBondContact O-CA 2.97Å; I507-D592 HydrophobicContact CB-CB 4.25Å; I507-D592 PolarHBondContact N-O 2.54Å; I507-D592 VanDerWaalsContact N-O 3.08Å; I507-D592 PolarHBondContact O-N 3.44Å
508I98.3Very high96.6Very high0 Ų027.1 Ų27.10%013%0.127CC..EExtended strand (participates in β ladder)trans-110.4129.2174.2-43.8178.4000107.8L469 L484 F486 V506 S524 M525 W567 F570 F590L469-I508 HydrophobicContact CD1-CG2 3.96Å; L469-I508 HydrophobicContact CD2-CD1 3.82Å; L469-I508 HydrophobicContact CD2-CG1 4.14Å; L469-I508 HydrophobicContact CD2-CG2 4.04Å; L484-I508 HydrophobicContact CD2-CB 4.47Å; L484-I508 HydrophobicContact CD2-CG2 3.27Å; L484-I508 HydrophobicContact CG-CG2 3.98Å; F486-I508 HydrophobicContact CB-CD1 4.06Å; V506-I508 HydrophobicContact CG1-CD1 4.28Å; V506-I508 HydrophobicContact CG1-CG1 3.77Å; I508-S524 CarbonylContact O-C 3.49Å; I508-S524 VanDerWaalsContact O-CA 3.31Å; I508-S524 WeakPolarHBondContact O-CA 3.43Å; I508-M525 PolarHBondContact N-O 2.87Å; I508-M525 PolarHBondContact O-N 3.08Å; I508-W567 HydrophobicContact CD1-CZ3 3.86Å; I508-W567 HydrophobicContact CG1-CZ3 4.36Å; I508-F570 HydrophobicContact CB-CE2 4.13Å; I508-F570 HydrophobicContact CB-CZ 4.27Å; I508-F570 HydrophobicContact CG2-CE2 4.3Å; I508-F570 HydrophobicContact CG2-CZ 4.29Å; I508-F570 WeakPolarHBondContact O-CZ 3.05Å; I508-F590 WeakPolarHBondContact CA-O 3.45Å
509T98Very high96.5Very high9 Ų923.6 Ų23.66%0.05511%0.112CC..EExtended strand (participates in β ladder)trans-128.5126.8-177.4-57.70000110.6S523 S524 M589 F590T509-S523 CarbonylContact C-O 3.6Å; T509-S523 VanDerWaalsContact CA-O 3.31Å; T509-S523 WeakPolarHBondContact CA-O 3.26Å; T509-S524 WeakPolarHBondContact CG2-OG 3.45Å; T509-S524 PolarHBondContact OG1-OG 2.85Å; T509-S524 VanDerWaalsContact OG1-OG 3.04Å; T509-M589 CarbonylContact O-C 3.54Å; T509-M589 VanDerWaalsContact O-CA 3.25Å; T509-M589 WeakPolarHBondContact O-CA 3.48Å; T509-F590 PolarHBondContact N-O 2.97Å; T509-F590 PolarHBondContact O-N 2.83Å
510I98.1Very high96.5Very high0 Ų022.1 Ų22.10%011%0.107CC..EExtended strand (participates in β ladder)trans-89.9118.1161.5-62.6174.5000107.2L484 D512 S522 S523 F570 I571 F581 L587 M589L484-I510 HydrophobicContact CD2-CD1 4.5Å; L484-I510 HydrophobicContact CD2-CG1 4.23Å; I510-D512 PolarHBondContact O-N 3.27Å; I510-S522 WeakPolarHBondContact O-CA 3.46Å; I510-S522 WeakPolarHBondContact O-CB 3.34Å; I510-S523 PolarHBondContact N-O 3.46Å; I510-S523 PolarHBondContact O-N 2.85Å; I510-F570 HydrophobicContact CB-CE1 4.25Å; I510-F570 HydrophobicContact CD1-CD1 3.44Å; I510-F570 VanDerWaalsContact CD1-CD1 3.44Å; I510-F570 HydrophobicContact CD1-CE1 3.58Å; I510-F570 HydrophobicContact CD1-CG 4.45Å; I510-F570 HydrophobicContact CG1-CD1 4.02Å; I510-F570 HydrophobicContact CG1-CE1 3.59Å; I510-F570 HydrophobicContact CG1-CZ 4.42Å; I510-I571 HydrophobicContact CD1-CB 4.4Å; I510-I571 HydrophobicContact CD1-CG2 3.57Å; I510-F581 HydrophobicContact CG2-CD1 3.8Å; I510-F581 HydrophobicContact CG2-CE1 4.39Å; I510-L587 HydrophobicContact CG2-CD1 3.61Å; I510-M589 HydrophobicContact CG1-CG 3.94Å
511L97.9Very high96.6Very high3 Ų321 Ų212%0.01610%0.1CC..  trans-73124.7-174.1178.666.1000111.1I390 Q513 I588 F590I390-L511 HydrophobicContact CD1-CD2 3.9Å; L511-Q513 HydrophobicContact CD2-CG 3.93Å; L511-Q513 HydrophobicContact CG-CG 4.01Å; L511-Q513 PolarHBondContact O-N 3.49Å; L511-I588 HydrophobicContact CB-CB 4.22Å; L511-I588 HydrophobicContact CB-CG2 4.34Å; L511-I588 HydrophobicContact CD2-CB 4.24Å; L511-I588 HydrophobicContact CD2-CD1 4.4Å; L511-I588 HydrophobicContact CD2-CG2 4.06Å; L511-I588 PolarHBondContact N-O 3.37Å; L511-F590 HydrophobicContact CB-CE2 4.44Å; L511-F590 HydrophobicContact CB-CZ 4.42Å; L511-F590 HydrophobicContact CD1-CE2 3.98Å; L511-F590 HydrophobicContact CD1-CZ 4.3Å; L511-F590 HydrophobicContact CD2-CE1 4.42Å; L511-F590 HydrophobicContact CD2-CE2 4.24Å; L511-F590 HydrophobicContact CD2-CZ 3.71Å; L511-F590 HydrophobicContact CG-CE2 4.45Å; L511-F590 HydrophobicContact CG-CZ 4.37Å
512D97.6Very high96.6Very high1 Ų121.7 Ų21.71%0.00510%0.104CC..  trans-75.9112.4156.7-177.911.4000107.9I510 E514 R520 M521 S522 R579 S580 F581I510-D512 PolarHBondContact O-N 3.27Å; D512-E514 PolarHBondContact O-N 3.44Å; D512-R520 HydrophobicContact CB-CB 4.41Å; D512-R520 VanDerWaalsContact O-CD 3.26Å; D512-R520 WeakPolarHBondContact O-CD 3.35Å; D512-R520 VanDerWaalsContact O-CG 3.23Å; D512-R520 WeakPolarHBondContact O-CG 3.3Å; D512-M521 PolarHBondContact OD2-N 2.85Å; D512-S522 PolarHBondContact N-OG 2.85Å; D512-S522 VanDerWaalsContact N-OG 3.1Å; D512-R579 IonicContact OD2-CZ 2.89Å; D512-R579 IonicContact OD2-NE 3.21Å; D512-R579 PolarHBondContact OD2-NE 3.02Å; D512-R579 IonicContact OD2-NH2 3.95Å; D512-S580 WeakPolarHBondContact OD1-CA 3.26Å; D512-S580 WeakPolarHBondContact OD1-CB 3Å; D512-S580 PolarHBondContact OD1-N 3.22Å; D512-F581 HydrophobicContact CB-CD1 4.23Å; D512-F581 HydrophobicContact CB-CE1 3.92Å; D512-F581 HydrophobicContact CB-CZ 4.31Å
513Q96.6Very high96.6Very high1 Ų119.9 Ų19.91%0.00510%0.097CC..  trans-83.529.7-172.8-53.1173.767.900112.6L511 P515 S580 F581 K583 D586 I588L511-Q513 HydrophobicContact CD2-CG 3.93Å; L511-Q513 HydrophobicContact CG-CG 4.01Å; L511-Q513 PolarHBondContact O-N 3.49Å; Q513-P515 WeakPolarHBondContact O-CD 3.16Å; Q513-S580 VanDerWaalsContact C-CB 3.5Å; Q513-S580 WeakPolarHBondContact CB-O 3.4Å; Q513-S580 VanDerWaalsContact CG-O 3.29Å; Q513-S580 WeakPolarHBondContact CG-O 3.42Å; Q513-S580 PolarHBondContact N-O 3.43Å; Q513-F581 PolarHBondContact NE2-O 2.96Å; Q513-K583 HydrophobicContact CB-CB 3.89Å; Q513-K583 HydrophobicContact CB-CD 3.7Å; Q513-K583 HydrophobicContact CB-CG 4.42Å; Q513-K583 HydrophobicContact CG-CB 4.3Å; Q513-K583 WeakPolarHBondContact O-CD 3.4Å; Q513-K583 PolarHBondContact O-NZ 2.9Å; Q513-D586 PolarHBondContact NE2-O 3.49Å; Q513-I588 HydrophobicContact CG-CD1 4.34Å; Q513-I588 VanDerWaalsContact OE1-CD1 3.23Å
514E95.1Very high96.5Very high56 Ų5618.1 Ų18.126%0.2629%0.088SC..  trans-56.9124.5169.3172.453.9-134.800109.2D512 D516 N519 R520D512-E514 PolarHBondContact O-N 3.44Å; E514-D516 PolarHBondContact O-N 2.78Å; E514-N519 HydrophobicContact CG-CB 3.81Å; E514-R520 HydrophobicContact CB-CG 3.89Å; E514-R520 WeakPolarHBondContact O-CG 3.33Å; E514-R520 PolarHBondContact O-NE 3.02Å
515P93.4Very high96.4Very high13 Ų1317.6 Ų17.68%0.0849%0.087CC..SBendtrans-50.3-51.1-178.4-34.138.3000113.2H268 T270 T303 D423 Q513 V517H268-P515 PolarHBondContact CE1-O 3.39Å; T270-P515 HydrophobicContact CG2-CB 3.76Å; T303-P515 HydrophobicContact CG2-CB 4.02Å; T303-P515 HydrophobicContact CG2-CG 3.62Å; D423-P515 WeakPolarHBondContact OD1-CB 3.37Å; Q513-P515 WeakPolarHBondContact O-CD 3.16Å; P515-V517 PolarHBondContact O-N 3.21Å
516D93.5Very high96.3Very high22 Ų2217.4 Ų17.412%0.1189%0.087CC..SBendtrans-77.6107.8177.4-168.2-21.8000110.4E514 R518 N519 R520E514-D516 PolarHBondContact O-N 2.78Å; D516-R518 PolarHBondContact O-N 2.92Å; D516-R518 WeakPolarHBondContact OD1-CB 3.43Å; D516-R518 WeakPolarHBondContact OD1-CG 3.31Å; D516-R518 IonicContact OD1-CZ 3.69Å; D516-R518 PolarHBondContact OD1-N 2.89Å; D516-R518 IonicContact OD1-NE 3.86Å; D516-R518 PolarHBondContact OD1-NE 3.09Å; D516-R518 IonicContact OD1-NH2 2.6Å; D516-R518 IonicContact OD2-CZ 2.7Å; D516-R518 IonicContact OD2-NE 3.42Å; D516-R518 PolarHBondContact OD2-NE 2.74Å; D516-R518 IonicContact OD2-NH2 3.24Å; D516-R518 PolarHBondContact OD2-NH2 3.16Å; D516-N519 PolarHBondContact O-N 3.41Å; D516-R520 PolarHBondContact O-N 3.43Å
517V94.5Very high96.2Very high12 Ų1217.6 Ų17.67%0.0739%0.087CC..G310 helixtrans-54.7-23.8-179.269.60000113.8L104 L265 T425 P515 N519L104-V517 HydrophobicContact CD1-CG1 4.31Å; L104-V517 HydrophobicContact CD1-CG2 4.48Å; L104-V517 HydrophobicContact CD2-CG2 4.13Å; L265-V517 HydrophobicContact CD1-CG1 3.67Å; L265-V517 HydrophobicContact CD2-CG1 4.25Å; T425-V517 HydrophobicContact CG2-CB 3.89Å; T425-V517 HydrophobicContact CG2-CG1 3.65Å; T425-V517 HydrophobicContact CG2-CG2 4.24Å; P515-V517 PolarHBondContact O-N 3.21Å; V517-N519 VanDerWaalsContact C-N 3.28Å; V517-N519 PolarHBondContact O-N 2.61Å
518R94.2Very high96.2Very high103 Ų10317.4 Ų17.439%0.3899%0.087SC..G310 helixtrans-70.3-27.6177.8-60.9172.7-68173.62.4112.4K105 L250 L265 D516K105-R518 WeakPolarHBondContact CE-O 3.23Å; L250-R518 VanDerWaalsContact CD1-O 3.24Å; L250-R518 WeakPolarHBondContact CD1-O 3.13Å; L265-R518 HydrophobicContact CD2-CG 3.94Å; D516-R518 PolarHBondContact O-N 2.92Å; D516-R518 WeakPolarHBondContact OD1-CB 3.43Å; D516-R518 WeakPolarHBondContact OD1-CG 3.31Å; D516-R518 IonicContact OD1-CZ 3.69Å; D516-R518 PolarHBondContact OD1-N 2.89Å; D516-R518 IonicContact OD1-NE 3.86Å; D516-R518 PolarHBondContact OD1-NE 3.09Å; D516-R518 IonicContact OD1-NH2 2.6Å; D516-R518 IonicContact OD2-CZ 2.7Å; D516-R518 IonicContact OD2-NE 3.42Å; D516-R518 PolarHBondContact OD2-NE 2.74Å; D516-R518 IonicContact OD2-NH2 3.24Å; D516-R518 PolarHBondContact OD2-NH2 3.16Å
519N95.4Very high96.1Very high56 Ų5617.4 Ų17.430%0.2999%0.087SC..G310 helixtrans-99.7-1.3-177-61.5-30.2000113.3E514 D516 V517 M521 R579E514-N519 HydrophobicContact CG-CB 3.81Å; D516-N519 PolarHBondContact O-N 3.41Å; V517-N519 VanDerWaalsContact C-N 3.28Å; V517-N519 PolarHBondContact O-N 2.61Å; N519-M521 PolarHBondContact O-N 2.84Å; N519-R579 PolarHBondContact O-NH2 2.93Å
520R96.4Very high96Very high14 Ų1418.6 Ų18.65%0.05310%0.096CC..  trans-65127.1175.8-68.7-177.6-172.5166.14.3110.5K105 D512 E514 D516K105-R520 PolarHBondContact NZ-O 3.38Å; D512-R520 HydrophobicContact CB-CB 4.41Å; D512-R520 VanDerWaalsContact O-CD 3.26Å; D512-R520 WeakPolarHBondContact O-CD 3.35Å; D512-R520 VanDerWaalsContact O-CG 3.23Å; D512-R520 WeakPolarHBondContact O-CG 3.3Å; E514-R520 HydrophobicContact CB-CG 3.89Å; E514-R520 WeakPolarHBondContact O-CG 3.33Å; E514-R520 PolarHBondContact O-NE 3.02Å; D516-R520 PolarHBondContact O-N 3.43Å
521M97.3Very high95.8Very high2 Ų223.5 Ų23.51%0.0112%0.117CC..  trans-11258.6173.3-60.8178.373.800110.1Q241 L243 D244 F245 D512 N519 R579 F581Q241-M521 VanDerWaalsContact CD-CE 3.49Å; Q241-M521 HydrophobicContact CG-CE 4.3Å; Q241-M521 VanDerWaalsContact NE2-CE 3.32Å; L243-M521 HydrophobicContact CB-CB 4.31Å; D244-M521 HydrophobicContact CB-CB 4.1Å; D244-M521 HydrophobicContact CB-CG 4.22Å; D244-M521 WeakPolarHBondContact O-CE 3.09Å; F245-M521 WeakPolarHBondContact O-CG 3.38Å; D512-M521 PolarHBondContact OD2-N 2.85Å; N519-M521 PolarHBondContact O-N 2.84Å; M521-R579 PolarHBondContact SD-NH1 3.28Å; M521-R579 VanDerWaalsContact SD-NH1 3.42Å; M521-F581 VanDerWaalsContact O-CZ 3.31Å; M521-F581 WeakPolarHBondContact O-CZ 3.27Å
522S97.3Very high95.4Very high15 Ų1530.5 Ų30.511%0.10515%0.154CC..  trans-61.9145.4-178.6-60.70000111.9I510 D512I510-S522 WeakPolarHBondContact O-CA 3.46Å; I510-S522 WeakPolarHBondContact O-CB 3.34Å; D512-S522 PolarHBondContact N-OG 2.85Å; D512-S522 VanDerWaalsContact N-OG 3.1Å
523S96.3Very high95.2Very high5 Ų532.2 Ų32.24%0.03516%0.162CC..EExtended strand (participates in β ladder)trans-88.9113.3177-173.10000109.7T509 I510 F570T509-S523 CarbonylContact C-O 3.6Å; T509-S523 VanDerWaalsContact CA-O 3.31Å; T509-S523 WeakPolarHBondContact CA-O 3.26Å; I510-S523 PolarHBondContact N-O 3.46Å; I510-S523 PolarHBondContact O-N 2.85Å; S523-F570 WeakPolarHBondContact O-CE1 3.41Å; S523-F570 PolarHBondContact OG-O 2.85Å
524S95.8Very high95Very high14 Ų1435.2 Ų35.210%0.09818%0.18CC..EExtended strand (participates in β ladder)trans-123.3131.8-176.6-54.90000112.1Y97 I508 T509Y97-S524 PolarHBondContact OH-OG 2.77Å; Y97-S524 VanDerWaalsContact OH-OG 3.09Å; I508-S524 CarbonylContact O-C 3.49Å; I508-S524 VanDerWaalsContact O-CA 3.31Å; I508-S524 WeakPolarHBondContact O-CA 3.43Å; T509-S524 WeakPolarHBondContact CG2-OG 3.45Å; T509-S524 PolarHBondContact OG1-OG 2.85Å; T509-S524 VanDerWaalsContact OG1-OG 3.04Å
525M94.9Very high94.6Very high10 Ų1032.8 Ų32.85%0.04917%0.169CC..EExtended strand (participates in β ladder)trans-123142175-60.8-67-177.100110.4Y149 I508 W567 F570Y149-M525 HydrophobicContact CD1-SD 3.87Å; Y149-M525 HydrophobicContact CE1-SD 3.87Å; I508-M525 PolarHBondContact N-O 2.87Å; I508-M525 PolarHBondContact O-N 3.08Å; M525-W567 HydrophobicContact CB-CD2 3.71Å; M525-W567 HydrophobicContact CB-CE3 3.61Å; M525-W567 HydrophobicContact CB-CH2 3.31Å; M525-W567 HydrophobicContact CB-CZ2 3.52Å; M525-W567 HydrophobicContact CB-CZ3 3.41Å; M525-W567 VanDerWaalsContact CB-CZ3 3.41Å; M525-W567 HydrophobicContact CG-CD2 3.95Å; M525-W567 HydrophobicContact CG-CE3 4.12Å; M525-W567 HydrophobicContact CG-CG 4.3Å; M525-W567 HydrophobicContact CG-CZ2 4.47Å; M525-W567 HydrophobicContact CG-CZ3 4.39Å; M525-F570 HydrophobicContact CB-CD2 4.29Å; M525-F570 HydrophobicContact CB-CE2 3.61Å; M525-F570 HydrophobicContact CB-CZ 4.1Å; M525-F570 HydrophobicContact CG-CD2 3.69Å; M525-F570 HydrophobicContact CG-CE1 4.39Å; M525-F570 HydrophobicContact CG-CE2 3.36Å; M525-F570 HydrophobicContact CG-CG 4.36Å; M525-F570 HydrophobicContact CG-CZ 3.76Å
526V95.8Very high94.3Very high11 Ų1136.8 Ų36.87%0.06720%0.195CC..EExtended strand (participates in β ladder)trans-132.1132.8-170.1-172.80000110.9N90 Y97 Q505 V506 I507N90-V526 PolarHBondContact ND2-O 2.91Å; Y97-V526 HydrophobicContact CD1-CG2 4.09Å; Y97-V526 HydrophobicContact CE1-CG2 4.3Å; Q505-V526 VanDerWaalsContact CD-CG1 3.41Å; Q505-V526 HydrophobicContact CG-CG1 3.5Å; V506-V526 WeakPolarHBondContact O-CA 3.28Å; I507-V526 HydrophobicContact CB-CG2 4.44Å; I507-V526 HydrophobicContact CG1-CG1 4.03Å; I507-V526 HydrophobicContact CG1-CG2 4.02Å; I507-V526 HydrophobicContact CG2-CG2 4.13Å
527F96.4Very high93.8Very high4 Ų439 Ų392%0.01821%0.21CC..EExtended strand (participates in β ladder)trans-143.1165.6166.674.7-91.7000111.7F37 N90 F486 Q505 V506 T529 W544 F565 W567F37-F527 HydrophobicContact CE1-CB 4.41Å; F37-F527 HydrophobicContact CE2-CB 3.86Å; F37-F527 AromaticContact CE2-CD1 3.84Å; F37-F527 HydrophobicContact CE2-CD1 3.84Å; F37-F527 AromaticContact CE2-CG 3.9Å; F37-F527 HydrophobicContact CE2-CG 3.9Å; F37-F527 HydrophobicContact CZ-CB 3.39Å; F37-F527 HydrophobicContact CZ-CD1 4.21Å; F37-F527 HydrophobicContact CZ-CD2 4.4Å; F37-F527 AromaticContact CZ-CG 3.78Å; F37-F527 HydrophobicContact CZ-CG 3.78Å; N90-F527 WeakPolarHBondContact OD1-CA 3.27Å; F486-F527 HydrophobicContact CB-CE1 4.08Å; F486-F527 HydrophobicContact CB-CZ 4.03Å; F486-F527 AromaticContact CD1-CZ 3.96Å; F486-F527 HydrophobicContact CD1-CZ 3.96Å; F486-F527 HydrophobicContact CG-CZ 4.17Å; Q505-F527 CarbonylContact C-O 3.59Å; Q505-F527 WeakPolarHBondContact CA-O 3.32Å; V506-F527 HydrophobicContact CB-CD1 4Å; V506-F527 HydrophobicContact CB-CE1 3.61Å; V506-F527 HydrophobicContact CB-CE2 4.13Å; V506-F527 HydrophobicContact CB-CG 4.44Å; V506-F527 HydrophobicContact CB-CZ 3.67Å; V506-F527 HydrophobicContact CG1-CD1 4.33Å; V506-F527 HydrophobicContact CG1-CE1 3.67Å; V506-F527 HydrophobicContact CG1-CZ 3.99Å; V506-F527 HydrophobicContact CG2-CE1 4.04Å; V506-F527 HydrophobicContact CG2-CE2 3.84Å; V506-F527 HydrophobicContact CG2-CZ 3.54Å; V506-F527 PolarHBondContact N-O 3.01Å; V506-F527 PolarHBondContact O-N 2.9Å; F527-T529 HydrophobicContact CE2-CG2 4.21Å; F527-W544 HydrophobicContact CD2-CZ2 4.42Å; F527-W544 AromaticContact CE2-CH2 3.72Å; F527-W544 HydrophobicContact CE2-CH2 3.72Å; F527-W544 AromaticContact CE2-CZ2 3.46Å; F527-W544 HydrophobicContact CE2-CZ2 3.46Å; F527-W544 VanDerWaalsContact CE2-CZ2 3.46Å; F527-W544 AromaticContact CZ-CH2 3.75Å; F527-W544 HydrophobicContact CZ-CH2 3.75Å; F527-W544 AromaticContact CZ-CZ2 3.97Å; F527-W544 HydrophobicContact CZ-CZ2 3.97Å; F527-F565 HydrophobicContact CD1-CD1 4.42Å; F527-F565 HydrophobicContact CD2-CD1 4.1Å; F527-F565 AromaticContact CD2-CE1 3.93Å; F527-F565 HydrophobicContact CD2-CE1 3.93Å; F527-F565 HydrophobicContact CE1-CD1 4.14Å; F527-F565 AromaticContact CE2-CD1 3.81Å; F527-F565 HydrophobicContact CE2-CD1 3.81Å; F527-F565 HydrophobicContact CE2-CE1 4.09Å; F527-F565 HydrophobicContact CG-CD1 4.42Å; F527-F565 HydrophobicContact CG-CE1 4.2Å; F527-F565 AromaticContact CZ-CD1 3.83Å; F527-F565 HydrophobicContact CZ-CD1 3.83Å; F527-F565 HydrophobicContact CZ-CE1 4.47Å; F527-W567 HydrophobicContact CB-CH2 4.39Å; F527-W567 HydrophobicContact CB-CZ2 4.33Å; F527-W567 AromaticContact CD1-CH2 3.47Å; F527-W567 HydrophobicContact CD1-CH2 3.47Å; F527-W567 VanDerWaalsContact CD1-CH2 3.47Å; F527-W567 HydrophobicContact CD1-CZ2 4.11Å; F527-W567 HydrophobicContact CD1-CZ3 4.04Å; F527-W567 HydrophobicContact CE1-CH2 4.25Å; F527-W567 HydrophobicContact CE1-CZ3 4.39Å; F527-W567 HydrophobicContact CG-CH2 4.41Å
528T97.2Very high93.5Very high14 Ų1439.7 Ų39.79%0.08621%0.213CC..EExtended strand (participates in β ladder)trans-118.4135175.5-57.70000110.3L89 N90 R504 H533 I596L89-T528 HydrophobicContact CD2-CG2 4.17Å; L89-T528 HydrophobicContact CG-CG2 4.43Å; N90-T528 VanDerWaalsContact CA-OG1 3.26Å; N90-T528 WeakPolarHBondContact CA-OG1 3.46Å; N90-T528 WeakPolarHBondContact CB-OG1 3.15Å; N90-T528 PolarHBondContact OD1-N 3.16Å; N90-T528 VanDerWaalsContact OD1-N 3.14Å; N90-T528 PolarHBondContact OD1-OG1 2.73Å; R504-T528 WeakPolarHBondContact O-CA 3.48Å; T528-H533 PolarHBondContact O-CE1 2.86Å; T528-I596 HydrophobicContact CG2-CD1 4.22Å; T528-I596 HydrophobicContact CG2-CG1 4.4Å
529T97.3Very high93.2Very high1 Ų141.6 Ų41.61%0.00623%0.231CC..  trans-64.3138.4178.5630000111.1V501 E502 N503 R504 F527 W544 F593V501-T529 WeakPolarHBondContact O-CB 3.01Å; V501-T529 PolarHBondContact O-OG1 3.15Å; E502-T529 VanDerWaalsContact C-OG1 3.32Å; E502-T529 WeakPolarHBondContact CA-OG1 3.24Å; N503-T529 PolarHBondContact N-O 3.03Å; N503-T529 PolarHBondContact N-OG1 3.08Å; R504-T529 PolarHBondContact N-OG1 3.19Å; R504-T529 PolarHBondContact O-N 3.24Å; F527-T529 HydrophobicContact CE2-CG2 4.21Å; T529-W544 HydrophobicContact CG2-CD2 3.85Å; T529-W544 HydrophobicContact CG2-CE3 4.28Å; T529-W544 HydrophobicContact CG2-CG 4.12Å; T529-W544 HydrophobicContact CG2-CZ2 4.32Å; T529-F593 HydrophobicContact CG2-CE2 3.79Å; T529-F593 HydrophobicContact CG2-CZ 4.29Å
530S94.7Very high92.7Very high34 Ų3443.8 Ų43.824%0.23824%0.242CC..  trans-150.8146.8-173.9178.10000111.5L532 H533 W544S530-L532 PolarHBondContact O-N 3.23Å; S530-L532 VanDerWaalsContact O-N 3.12Å; S530-L532 PolarHBondContact OG-N 2.82Å; S530-H533 WeakPolarHBondContact O-CB 3.47Å; S530-H533 PolarHBondContact O-N 3.07Å; S530-W544 VanDerWaalsContact O-CD1 3.27Å
531K94.3Very high92.5Very high103 Ų10345.9 Ų45.945%0.44826%0.257SS..THydrogen-bonded Turntrans-58.6-18.2169.6-80.1173.2177.4145.30114.1P500 E502 H533 V542P500-K531 HydrophobicContact CG-CD 4.32Å; P500-K531 HydrophobicContact CG-CG 3.79Å; E502-K531 HydrophobicContact CG-CD 4.5Å; E502-K531 HydrophobicContact CG-CG 4.04Å; E502-K531 WeakPolarHBondContact OE1-CE 3.35Å; E502-K531 IonicContact OE1-NZ 2.6Å; E502-K531 PolarHBondContact OE1-NZ 2.95Å; E502-K531 WeakPolarHBondContact OE2-CD 3.32Å; E502-K531 VanDerWaalsContact OE2-CG 3.28Å; E502-K531 WeakPolarHBondContact OE2-CG 3.49Å; E502-K531 IonicContact OE2-NZ 3.62Å; K531-H533 PolarHBondContact O-N 2.78Å; K531-V542 HydrophobicContact CB-CG2 4.43Å; K531-V542 HydrophobicContact CG-CG2 4.41Å
532L90.6Very high92.3Very high149 Ų14947.1 Ų47.178%0.7826%0.264SS*.THydrogen-bonded Turntrans-74.6-16.4175.9-60.7178.9000112.8S530 T534S530-L532 PolarHBondContact O-N 3.23Å; S530-L532 VanDerWaalsContact O-N 3.12Å; S530-L532 PolarHBondContact OG-N 2.82Å; L532-T534 PolarHBondContact O-N 3.35Å
533H92.5Very high92.2Very high38 Ų3846.5 Ų46.518%0.17626%0.26CS..  trans-80.987.8176-59174.2000108.6T528 S530 K531 I543 W544 F565T528-H533 PolarHBondContact O-CE1 2.86Å; S530-H533 WeakPolarHBondContact O-CB 3.47Å; S530-H533 PolarHBondContact O-N 3.07Å; K531-H533 PolarHBondContact O-N 2.78Å; H533-I543 HydrophobicContact CB-CD1 4.31Å; H533-I543 WeakPolarHBondContact O-CG1 3.2Å; H533-I543 PolarHBondContact O-N 2.8Å; H533-W544 AromaticContact CG-NE1 3.55Å; H533-W544 AromaticContact ND1-CE2 3.75Å; H533-W544 AromaticContact ND1-CZ2 3.84Å; H533-W544 AromaticContact ND1-NE1 3.06Å; H533-W544 PolarHBondContact ND1-NE1 3.08Å; H533-F565 AromaticContact CE1-CE1 3.71Å; H533-F565 AromaticContact CE1-CZ 3.84Å; H533-F565 AromaticContact CG-CZ 3.94Å; H533-F565 AromaticContact ND1-CE1 3.57Å; H533-F565 AromaticContact ND1-CZ 3.68Å
534T91.6Very high92.2Very high63 Ų6346.2 Ų46.239%0.38726%0.258SS..EExtended strand (participates in β ladder)trans-109161.6175.362.40000110.9L532 D540 T541 V542L532-T534 PolarHBondContact O-N 3.35Å; T534-D540 WeakPolarHBondContact CB-O 3.48Å; T534-D540 WeakPolarHBondContact CG2-O 3.39Å; T534-T541 VanDerWaalsContact CA-O 3.25Å; T534-T541 WeakPolarHBondContact CA-O 3.23Å; T534-T541 WeakPolarHBondContact CB-O 3.38Å; T534-V542 HydrophobicContact CG2-CG2 4.4Å
535S87.9Confident92.2Very high5 Ų547.4 Ų47.44%0.03526%0.263CS..EExtended strand (participates in β ladder)trans-137.5132.1175.9174.50000111.9V537 I538 D540 T541 I563S535-V537 PolarHBondContact O-N 3.31Å; S535-V537 VanDerWaalsContact O-N 3.08Å; S535-V537 WeakPolarHBondContact OG-CB 3.45Å; S535-V537 VanDerWaalsContact OG-CG2 3.22Å; S535-V537 WeakPolarHBondContact OG-CG2 3.36Å; S535-V537 PolarHBondContact OG-N 3.08Å; S535-I538 VanDerWaalsContact O-CG1 3.27Å; S535-I538 WeakPolarHBondContact O-CG1 3.4Å; S535-I538 PolarHBondContact O-N 3.14Å; S535-I538 VanDerWaalsContact O-N 3.11Å; S535-D540 VanDerWaalsContact O-CA 3.31Å; S535-D540 WeakPolarHBondContact O-CA 3.47Å; S535-D540 PolarHBondContact O-N 2.78Å; S535-T541 PolarHBondContact N-O 3.26Å; S535-I563 WeakPolarHBondContact OG-CD1 3.29Å
536P85.9Confident92.3Very high97 Ų9750.2 Ų50.263%0.6327%0.273SS*.G310 helixtrans-57.3-25.5175.9-25.433.8000113.5I538 N539 D540P536-I538 PolarHBondContact O-N 3.13Å; P536-N539 PolarHBondContact O-N 3.15Å; P536-D540 VanDerWaalsContact CA-OD1 3.31Å; P536-D540 WeakPolarHBondContact CA-OD1 3.12Å
537V83.5Confident92.3Very high70 Ų7049.7 Ų49.742%0.42427%0.27SS..G310 helixtrans-62.4-32.6-179.3-176.60000111.8H33 S535 I563H33-V537 HydrophobicContact CB-CB 4.03Å; H33-V537 HydrophobicContact CB-CG1 3.72Å; H33-V537 HydrophobicContact CB-CG2 3.1Å; S535-V537 PolarHBondContact O-N 3.31Å; S535-V537 VanDerWaalsContact O-N 3.08Å; S535-V537 WeakPolarHBondContact OG-CB 3.45Å; S535-V537 VanDerWaalsContact OG-CG2 3.22Å; S535-V537 WeakPolarHBondContact OG-CG2 3.36Å; S535-V537 PolarHBondContact OG-N 3.08Å; V537-I563 HydrophobicContact CB-CD1 4.02Å; V537-I563 HydrophobicContact CG1-CD1 4.3Å
538I87.3Confident92.3Very high26 Ų2651.8 Ų51.813%0.13329%0.285CS..G310 helixtrans-10933.5177.352.9173.3000110.1S535 P536 D540 T541 I543 V550 I563S535-I538 VanDerWaalsContact O-CG1 3.27Å; S535-I538 WeakPolarHBondContact O-CG1 3.4Å; S535-I538 PolarHBondContact O-N 3.14Å; S535-I538 VanDerWaalsContact O-N 3.11Å; P536-I538 PolarHBondContact O-N 3.13Å; I538-D540 PolarHBondContact O-N 2.83Å; I538-T541 WeakPolarHBondContact CB-OG1 3.35Å; I538-T541 WeakPolarHBondContact CD1-O 3.09Å; I538-T541 WeakPolarHBondContact CD1-OG1 3.41Å; I538-T541 VanDerWaalsContact CG1-OG1 3.3Å; I538-T541 WeakPolarHBondContact CG1-OG1 3.41Å; I538-T541 WeakPolarHBondContact O-CB 3.31Å; I538-T541 WeakPolarHBondContact O-CG2 3.36Å; I538-T541 PolarHBondContact O-N 3.16Å; I538-T541 PolarHBondContact O-OG1 3.05Å; I538-I543 HydrophobicContact CD1-CG1 4.31Å; I538-V550 HydrophobicContact CD1-CB 4.26Å; I538-V550 WeakPolarHBondContact CG2-O 3.42Å; I538-I563 HydrophobicContact CB-CD1 4.37Å; I538-I563 HydrophobicContact CD1-CD1 3.83Å; I538-I563 HydrophobicContact CG1-CD1 3.82Å; I538-I563 HydrophobicContact CG2-CD1 3.76Å; I538-I563 HydrophobicContact CG2-CG1 4.4Å
539N87.9Confident92.1Very high143 Ų14360 Ų6077%0.76532%0.315SS*.THydrogen-bonded Turntrans57.244.8-179.9-54.7-42.3000113.3P536 T541P536-N539 PolarHBondContact O-N 3.15Å; N539-T541 PolarHBondContact O-N 3.4Å; N539-T541 VanDerWaalsContact O-N 3.13Å
540D86.6Confident91.9Very high102 Ų10260.9 Ų60.955%0.54532%0.32SS..THydrogen-bonded Turntrans57.825-179.2-60-51.9000113.8T534 S535 P536 I538T534-D540 WeakPolarHBondContact CB-O 3.48Å; T534-D540 WeakPolarHBondContact CG2-O 3.39Å; S535-D540 VanDerWaalsContact O-CA 3.31Å; S535-D540 WeakPolarHBondContact O-CA 3.47Å; S535-D540 PolarHBondContact O-N 2.78Å; P536-D540 VanDerWaalsContact CA-OD1 3.31Å; P536-D540 WeakPolarHBondContact CA-OD1 3.12Å; I538-D540 PolarHBondContact O-N 2.83Å
541T90.6Very high91.9Very high58 Ų5860.2 Ų60.236%0.35632%0.318SS..EExtended strand (participates in β ladder)trans-80163.3170.659.70000111.6T534 S535 I538 N539 I543T534-T541 VanDerWaalsContact CA-O 3.25Å; T534-T541 WeakPolarHBondContact CA-O 3.23Å; T534-T541 WeakPolarHBondContact CB-O 3.38Å; S535-T541 PolarHBondContact N-O 3.26Å; I538-T541 WeakPolarHBondContact CB-OG1 3.35Å; I538-T541 WeakPolarHBondContact CD1-O 3.09Å; I538-T541 WeakPolarHBondContact CD1-OG1 3.41Å; I538-T541 VanDerWaalsContact CG1-OG1 3.3Å; I538-T541 WeakPolarHBondContact CG1-OG1 3.41Å; I538-T541 WeakPolarHBondContact O-CB 3.31Å; I538-T541 WeakPolarHBondContact O-CG2 3.36Å; I538-T541 PolarHBondContact O-N 3.16Å; I538-T541 PolarHBondContact O-OG1 3.05Å; N539-T541 PolarHBondContact O-N 3.4Å; N539-T541 VanDerWaalsContact O-N 3.13Å; T541-I543 PolarHBondContact O-N 3.05Å
542V94.1Very high91.9Very high28 Ų2858.6 Ų58.617%0.1732%0.317CS..EExtended strand (participates in β ladder)trans-70.9126.6-176.6-177.70000110P500 K531 T534 W544 D545P500-V542 HydrophobicContact CB-CB 4.37Å; P500-V542 HydrophobicContact CB-CG1 3.78Å; P500-V542 HydrophobicContact CG-CG1 4.3Å; K531-V542 HydrophobicContact CB-CG2 4.43Å; K531-V542 HydrophobicContact CG-CG2 4.41Å; T534-V542 HydrophobicContact CG2-CG2 4.4Å; V542-W544 HydrophobicContact CG1-CB 4.29Å; V542-W544 PolarHBondContact O-N 2.95Å; V542-D545 PolarHBondContact O-N 3.49Å
543I94.4Very high92.1Very high1 Ų157.1 Ų57.11%0.00530%0.302CS..THydrogen-bonded Turntrans-59.2-33.9-179.1-65.6170.8000111.5A35 H533 I538 T541 D545 I563 F565A35-I543 HydrophobicContact CB-CD1 3.81Å; H533-I543 HydrophobicContact CB-CD1 4.31Å; H533-I543 WeakPolarHBondContact O-CG1 3.2Å; H533-I543 PolarHBondContact O-N 2.8Å; I538-I543 HydrophobicContact CD1-CG1 4.31Å; T541-I543 PolarHBondContact O-N 3.05Å; I543-D545 VanDerWaalsContact C-N 3.35Å; I543-D545 PolarHBondContact O-N 3.48Å; I543-I563 HydrophobicContact CG2-CB 4.23Å; I543-F565 HydrophobicContact CD1-CD2 4.1Å
544W96.6Very high92Very high0 Ų055.9 Ų55.90%030%0.296CS..THydrogen-bonded Turntrans-89.813.6-177-43.7118.9000114.6F486 V488 P500 V501 F527 T529 S530 H533 V542 F565F486-W544 AromaticContact CD1-CH2 3.94Å; F486-W544 HydrophobicContact CD1-CH2 3.94Å; F486-W544 AromaticContact CD1-CZ3 3.77Å; F486-W544 HydrophobicContact CD1-CZ3 3.77Å; F486-W544 HydrophobicContact CE1-CH2 4.46Å; F486-W544 AromaticContact CE1-CZ3 3.97Å; F486-W544 HydrophobicContact CE1-CZ3 3.97Å; V488-W544 HydrophobicContact CG2-CE3 3.88Å; V488-W544 HydrophobicContact CG2-CZ3 4.12Å; P500-W544 CarbonylContact C-O 3.53Å; P500-W544 WeakPolarHBondContact CA-O 3.48Å; P500-W544 HydrophobicContact CB-CB 4.5Å; P500-W544 WeakPolarHBondContact CB-O 3.4Å; V501-W544 HydrophobicContact CB-CB 4.32Å; V501-W544 PolarHBondContact N-O 3.32Å; V501-W544 WeakPolarHBondContact O-CB 3.48Å; F527-W544 HydrophobicContact CD2-CZ2 4.42Å; F527-W544 AromaticContact CE2-CH2 3.72Å; F527-W544 HydrophobicContact CE2-CH2 3.72Å; F527-W544 AromaticContact CE2-CZ2 3.46Å; F527-W544 HydrophobicContact CE2-CZ2 3.46Å; F527-W544 VanDerWaalsContact CE2-CZ2 3.46Å; F527-W544 AromaticContact CZ-CH2 3.75Å; F527-W544 HydrophobicContact CZ-CH2 3.75Å; F527-W544 AromaticContact CZ-CZ2 3.97Å; F527-W544 HydrophobicContact CZ-CZ2 3.97Å; T529-W544 HydrophobicContact CG2-CD2 3.85Å; T529-W544 HydrophobicContact CG2-CE3 4.28Å; T529-W544 HydrophobicContact CG2-CG 4.12Å; T529-W544 HydrophobicContact CG2-CZ2 4.32Å; S530-W544 VanDerWaalsContact O-CD1 3.27Å; H533-W544 AromaticContact CG-NE1 3.55Å; H533-W544 AromaticContact ND1-CE2 3.75Å; H533-W544 AromaticContact ND1-CZ2 3.84Å; H533-W544 AromaticContact ND1-NE1 3.06Å; H533-W544 PolarHBondContact ND1-NE1 3.08Å; V542-W544 HydrophobicContact CG1-CB 4.29Å; V542-W544 PolarHBondContact O-N 2.95Å; W544-F565 HydrophobicContact CH2-CB 3.64Å; W544-F565 AromaticContact CH2-CD1 3.93Å; W544-F565 HydrophobicContact CH2-CD1 3.93Å; W544-F565 HydrophobicContact CH2-CG 4.06Å; W544-F565 HydrophobicContact CZ2-CB 3.98Å; W544-F565 AromaticContact CZ2-CD1 3.57Å; W544-F565 HydrophobicContact CZ2-CD1 3.57Å; W544-F565 HydrophobicContact CZ2-CE1 4.16Å; W544-F565 AromaticContact CZ2-CG 3.88Å; W544-F565 HydrophobicContact CZ2-CG 3.88Å
545D96.4Very high91.9Very high38 Ų3858.7 Ų58.720%0.20331%0.313CS..SBendtrans-71.8171.6167.4-158.6-7.7000110.2W499 P500 V542 I543 P547 V550W499-D545 VanDerWaalsContact CE3-C 3.47Å; P500-D545 HydrophobicContact CB-CB 4.39Å; V542-D545 PolarHBondContact O-N 3.49Å; I543-D545 VanDerWaalsContact C-N 3.35Å; I543-D545 PolarHBondContact O-N 3.48Å; D545-P547 WeakPolarHBondContact O-CD 2.89Å; D545-V550 HydrophobicContact CB-CG1 3.85Å; D545-V550 HydrophobicContact CB-CG2 3.99Å; D545-V550 WeakPolarHBondContact O-CG2 3.41Å
546R96.6Very high91.8Very high69 Ų6960.8 Ų60.826%0.2632%0.324SS..  trans-54.7124-174.4-170.9175.4175.6169.81.6110.9D494 W499 S548 R549 V550D494-R546 IonicContact OD2-NE 2.67Å; W499-R546 HydrophobicContact CB-CB 4.43Å; W499-R546 HydrophobicContact CD2-CB 3.79Å; W499-R546 HydrophobicContact CD2-CG 4.25Å; W499-R546 VanDerWaalsContact CE3-CA 3.49Å; W499-R546 HydrophobicContact CE3-CB 4.22Å; W499-R546 HydrophobicContact CG-CB 3.86Å; W499-R546 HydrophobicContact CG-CG 4.47Å; W499-R546 HydrophobicContact CZ2-CG 4.34Å; R546-S548 WeakPolarHBondContact CD-OG 3.37Å; R546-S548 PolarHBondContact NE-OG 3.11Å; R546-S548 PolarHBondContact O-N 2.98Å; R546-R549 HydrophobicContact CB-CG 4.42Å; R546-R549 WeakPolarHBondContact O-CA 3.47Å; R546-R549 WeakPolarHBondContact O-CB 3.49Å; R546-R549 PolarHBondContact O-N 3.01Å; R546-V550 PolarHBondContact O-N 3.23Å
547P96.6Very high91.8Very high0 Ų057.6 Ų57.60%030%0.304CS..Hα-helixtrans-57.7-29.9-176.1-29.435.4000113.9V488 W499 D545 R549 G551 F560V488-P547 HydrophobicContact CB-CG 4.15Å; V488-P547 HydrophobicContact CG1-CG 3.86Å; W499-P547 VanDerWaalsContact CH2-CD 3.41Å; W499-P547 HydrophobicContact CH2-CG 4.22Å; W499-P547 HydrophobicContact CZ3-CG 4.46Å; D545-P547 WeakPolarHBondContact O-CD 2.89Å; P547-R549 PolarHBondContact O-N 3.31Å; P547-R549 VanDerWaalsContact O-N 3.12Å; P547-G551 WeakPolarHBondContact O-CA 3.5Å; P547-G551 PolarHBondContact O-N 3.19Å; P547-F560 HydrophobicContact CB-CB 3.97Å; P547-F560 WeakPolarHBondContact CB-O 3.4Å; P547-F560 VanDerWaalsContact O-CB 3.31Å; P547-F560 WeakPolarHBondContact O-CB 3.09Å
548S95.1Very high92.2Very high49 Ų4959.8 Ų59.834%0.34331%0.313SS..Hα-helixtrans-65.8-11.5174.372.50000114.6R546R546-S548 WeakPolarHBondContact CD-OG 3.37Å; R546-S548 PolarHBondContact NE-OG 3.11Å; R546-S548 PolarHBondContact O-N 2.98Å
549R93.8Very high92.5Very high186 Ų18658.6 Ų58.670%0.70231%0.307SS*.Hα-helixtrans-107.5-44.9178.8-66.3-177.2174.7174.8-0.7112.4R546 P547R546-R549 HydrophobicContact CB-CG 4.42Å; R546-R549 WeakPolarHBondContact O-CA 3.47Å; R546-R549 WeakPolarHBondContact O-CB 3.49Å; R546-R549 PolarHBondContact O-N 3.01Å; P547-R549 PolarHBondContact O-N 3.31Å; P547-R549 VanDerWaalsContact O-N 3.12Å
550V93.6Very high93Very high20 Ų2055.2 Ų55.212%0.12129%0.286CS..Hα-helixtrans-108.7-11.3-173.5-620000113.8I538 D545 R546I538-V550 HydrophobicContact CD1-CB 4.26Å; I538-V550 WeakPolarHBondContact CG2-O 3.42Å; D545-V550 HydrophobicContact CB-CG1 3.85Å; D545-V550 HydrophobicContact CB-CG2 3.99Å; D545-V550 WeakPolarHBondContact O-CG2 3.41Å; R546-V550 PolarHBondContact O-N 3.23Å
551G93.4Very high93.4Very high19 Ų1950.9 Ų50.920%0.19626%0.262CS..SBendtrans-93.1178-176.700000114.1P547 R561P547-G551 WeakPolarHBondContact O-CA 3.5Å; P547-G551 PolarHBondContact O-N 3.19Å; G551-R561 CarbonylContact C-O 3.57Å; G551-R561 WeakPolarHBondContact CA-O 3.38Å
552T94.1Very high93.6Very high69 Ų6948.4 Ų48.442%0.42325%0.247SC..EExtended strand (participates in β ladder)trans-110.9140.1177.553.40000110.2H554 F560 R561T552-H554 PolarHBondContact O-CD2 2.95Å; T552-H554 PolarHBondContact OG1-NE2 3.28Å; T552-F560 CarbonylContact O-C 3.6Å; T552-F560 VanDerWaalsContact O-CA 3.23Å; T552-F560 WeakPolarHBondContact O-CA 3.14Å; T552-R561 PolarHBondContact N-O 2.87Å; T552-R561 PolarHBondContact O-N 3.38Å
553Y94.8Very high93.5Very high119 Ų11947.6 Ų47.647%0.46724%0.241SC..EExtended strand (participates in β ladder)trans-78.2131.3-179.1178.3-101.7000111.1T555 D558 F560Y553-T555 HydrophobicContact CD1-CG2 4.46Å; Y553-T555 HydrophobicContact CE1-CG2 3.86Å; Y553-D558 WeakPolarHBondContact CE2-OD1 3.36Å; Y553-D558 PolarHBondContact OH-OD1 2.54Å; Y553-F560 HydrophobicContact CD2-CD2 4.11Å; Y553-F560 AromaticContact CD2-CE2 3.87Å; Y553-F560 HydrophobicContact CD2-CE2 3.87Å; Y553-F560 HydrophobicContact CD2-CZ 4.1Å; Y553-F560 HydrophobicContact CG-CZ 4.44Å
554H91.5Very high93.4Very high12 Ų1247.9 Ų47.96%0.05624%0.243CC..EExtended strand (participates in β ladder)trans-121.4119.5-176.6-80.4-79.1000110.5T552 D556 D558 C559 R561T552-H554 PolarHBondContact O-CD2 2.95Å; T552-H554 PolarHBondContact OG1-NE2 3.28Å; H554-D556 VanDerWaalsContact C-N 3.29Å; H554-D556 WeakPolarHBondContact CB-OD1 3.38Å; H554-D556 IonicContact CG-OD1 4Å; H554-D556 IonicContact ND1-OD1 3.02Å; H554-D556 PolarHBondContact O-N 3.11Å; H554-D558 WeakPolarHBondContact O-CA 3.3Å; H554-D558 PolarHBondContact O-N 3.38Å; H554-D558 VanDerWaalsContact O-N 3.08Å; H554-C559 WeakPolarHBondContact CB-O 3.48Å; H554-C559 PolarHBondContact N-O 3.09Å; H554-C559 PolarHBondContact O-N 3.38Å; H554-R561 VanDerWaalsContact CB-NH1 3.32Å; H554-R561 VanDerWaalsContact CG-NH1 3.26Å; H554-R561 PolarHBondContact ND1-NH1 3.44Å
555T89.8Confident93.2Very high121 Ų12148.5 Ų48.574%0.74225%0.246SC*.THydrogen-bonded Turntrans-71.4-22.8-176.255.10000113.4Y553Y553-T555 HydrophobicContact CD1-CG2 4.46Å; Y553-T555 HydrophobicContact CE1-CG2 3.86Å
556D85.1Confident93Very high49 Ų4946.7 Ų46.726%0.26224%0.236SC..THydrogen-bonded Turntrans-72.1-33-178.158.3-63.8000113.2K25 H554 R561K25-D556 HydrophobicContact CD-CB 4.17Å; H554-D556 VanDerWaalsContact C-N 3.29Å; H554-D556 WeakPolarHBondContact CB-OD1 3.38Å; H554-D556 IonicContact CG-OD1 4Å; H554-D556 IonicContact ND1-OD1 3.02Å; H554-D556 PolarHBondContact O-N 3.11Å; D556-R561 IonicContact OD1-NH1 3.32Å; D556-R561 PolarHBondContact OD1-NH1 3.44Å; D556-R561 VanDerWaalsContact OD1-NH1 3.15Å; D556-R561 IonicContact OD2-CZ 3.4Å; D556-R561 IonicContact OD2-NH1 3.78Å; D556-R561 PolarHBondContact OD2-NH1 3.22Å; D556-R561 IonicContact OD2-NH2 3.8Å; D556-R561 PolarHBondContact OD2-NH2 2.93Å
557C86.8Confident92.8Very high30 Ų3043.8 Ų43.820%0.20323%0.225CC..THydrogen-bonded Turntrans-105.9-4.4175.763.40000113.4C559C557-C559 HydrophobicContact CB-CB 4Å; C557-C559 WeakPolarHBondContact CB-SG 3.41Å; C557-C559 PolarHBondContact O-N 3.02Å; C557-C559 WeakPolarHBondContact SG-CB 3.29Å; C557-C559 PolarHBondContact SG-N 3.49Å; C557-C559 VanDerWaalsContact SG-N 3.38Å; C557-C559 CovalentContact SG-SG 2.05Å; C557-C559 PolarHBondContact SG-SG 2.99Å
558D91.3Very high92.4Very high117 Ų11745.7 Ų45.763%0.62624%0.238SC*.THydrogen-bonded Turntrans46.550.8-166.7-169.324000111.4Y553 H554Y553-D558 WeakPolarHBondContact CE2-OD1 3.36Å; Y553-D558 PolarHBondContact OH-OD1 2.54Å; H554-D558 WeakPolarHBondContact O-CA 3.3Å; H554-D558 PolarHBondContact O-N 3.38Å; H554-D558 VanDerWaalsContact O-N 3.08Å
559C94.6Very high92Very high1 Ų145.3 Ų45.31%0.00724%0.242CC..EExtended strand (participates in β ladder)trans-149.1154.6-171.181.70000111.8H554 C557H554-C559 WeakPolarHBondContact CB-O 3.48Å; H554-C559 PolarHBondContact N-O 3.09Å; H554-C559 PolarHBondContact O-N 3.38Å; C557-C559 HydrophobicContact CB-CB 4Å; C557-C559 WeakPolarHBondContact CB-SG 3.41Å; C557-C559 PolarHBondContact O-N 3.02Å; C557-C559 WeakPolarHBondContact SG-CB 3.29Å; C557-C559 PolarHBondContact SG-N 3.49Å; C557-C559 VanDerWaalsContact SG-N 3.38Å; C557-C559 CovalentContact SG-SG 2.05Å; C557-C559 PolarHBondContact SG-SG 2.99Å
560F96.7Very high91.9Very high72 Ų7236.8 Ų36.832%0.31621%0.21SC..EExtended strand (participates in β ladder)trans-84.7136.2166.8-67.8-100.6000109.7C489 S490 P547 T552 Y553C489-F560 CarbonylContact C-O 3.31Å; C489-F560 VanDerWaalsContact CA-O 3.32Å; C489-F560 WeakPolarHBondContact CA-O 3.19Å; S490-F560 PolarHBondContact N-O 3.03Å; S490-F560 PolarHBondContact OG-N 3.23Å; P547-F560 HydrophobicContact CB-CB 3.97Å; P547-F560 WeakPolarHBondContact CB-O 3.4Å; P547-F560 VanDerWaalsContact O-CB 3.31Å; P547-F560 WeakPolarHBondContact O-CB 3.09Å; T552-F560 CarbonylContact O-C 3.6Å; T552-F560 VanDerWaalsContact O-CA 3.23Å; T552-F560 WeakPolarHBondContact O-CA 3.14Å; Y553-F560 HydrophobicContact CD2-CD2 4.11Å; Y553-F560 AromaticContact CD2-CE2 3.87Å; Y553-F560 HydrophobicContact CD2-CE2 3.87Å; Y553-F560 HydrophobicContact CD2-CZ 4.1Å; Y553-F560 HydrophobicContact CG-CZ 4.44Å
561R95.6Very high91.8Very high10 Ų1036.2 Ų36.24%0.03821%0.206CC..EExtended strand (participates in β ladder)trans-114138.4173.3-63.6-177171.6119.8-9.1110.5Q455 H487 V488 G551 T552 H554 D556Q455-R561 VanDerWaalsContact OE1-CZ 3.29Å; H487-R561 PolarHBondContact NE2-NE 2.74Å; V488-R561 WeakPolarHBondContact O-CA 3.23Å; G551-R561 CarbonylContact C-O 3.57Å; G551-R561 WeakPolarHBondContact CA-O 3.38Å; T552-R561 PolarHBondContact N-O 2.87Å; T552-R561 PolarHBondContact O-N 3.38Å; H554-R561 VanDerWaalsContact CB-NH1 3.32Å; H554-R561 VanDerWaalsContact CG-NH1 3.26Å; H554-R561 PolarHBondContact ND1-NH1 3.44Å; D556-R561 IonicContact OD1-NH1 3.32Å; D556-R561 PolarHBondContact OD1-NH1 3.44Å; D556-R561 VanDerWaalsContact OD1-NH1 3.15Å; D556-R561 IonicContact OD2-CZ 3.4Å; D556-R561 IonicContact OD2-NH1 3.78Å; D556-R561 PolarHBondContact OD2-NH1 3.22Å; D556-R561 IonicContact OD2-NH2 3.8Å; D556-R561 PolarHBondContact OD2-NH2 2.93Å
562S94.6Very high91.7Very high6 Ų636.4 Ų36.44%0.04221%0.205CC..PPolyproline II helixtrans-63.9171.1169.1720000110.8H487 V488H487-S562 WeakPolarHBondContact CA-OG 3.35Å; V488-S562 PolarHBondContact N-OG 3.27Å; V488-S562 PolarHBondContact O-N 3.34Å
563I91.8Very high91.5Very high11 Ų1135 Ų356%0.05619%0.193CC..PPolyproline II helixtrans-58.7140.1169-63.7177.7000109.5H33 D34 S535 V537 I538 I543 F565H33-I563 VanDerWaalsContact O-CG2 3.29Å; H33-I563 WeakPolarHBondContact O-CG2 3.41Å; D34-I563 HydrophobicContact CB-CG2 4.46Å; S535-I563 WeakPolarHBondContact OG-CD1 3.29Å; V537-I563 HydrophobicContact CB-CD1 4.02Å; V537-I563 HydrophobicContact CG1-CD1 4.3Å; I538-I563 HydrophobicContact CB-CD1 4.37Å; I538-I563 HydrophobicContact CD1-CD1 3.83Å; I538-I563 HydrophobicContact CG1-CD1 3.82Å; I538-I563 HydrophobicContact CG2-CD1 3.76Å; I538-I563 HydrophobicContact CG2-CG1 4.4Å; I543-I563 HydrophobicContact CG2-CB 4.23Å; I563-F565 PolarHBondContact O-N 3.24Å
564D92.3Very high91.2Very high7 Ų734.2 Ų34.24%0.03719%0.194CC..PPolyproline II helixtrans-67.6129.3173.2-77.8-32000109.9D34 A35 T470 Y472 A485 H487D34-D564 HydrophobicContact CB-CB 4.19Å; D34-D564 WeakPolarHBondContact CB-O 3.45Å; A35-D564 PolarHBondContact N-O 2.9Å; T470-D564 WeakPolarHBondContact CB-OD1 3.34Å; T470-D564 VanDerWaalsContact CB-OD2 3.3Å; T470-D564 WeakPolarHBondContact CB-OD2 3.48Å; T470-D564 VanDerWaalsContact CG2-OD2 3.3Å; T470-D564 WeakPolarHBondContact CG2-OD2 3.22Å; T470-D564 VanDerWaalsContact OG1-CG 3.28Å; T470-D564 PolarHBondContact OG1-OD1 3.39Å; T470-D564 PolarHBondContact OG1-OD2 3.26Å; Y472-D564 PolarHBondContact OH-OD2 3.2Å; A485-D564 HydrophobicContact CB-CB 3.75Å; H487-D564 IonicContact CG-OD1 3.34Å; H487-D564 IonicContact ND1-OD1 3.3Å; H487-D564 PolarHBondContact ND1-OD1 3.21Å; H487-D564 VanDerWaalsContact ND1-OD1 3.13Å
565F93.4Very high91Very high14 Ų1435.1 Ų35.16%0.06120%0.199CC..EExtended strand (participates in β ladder)trans-125.7123.4176.7-171.2-106.7000110.6A35 F37 A485 F486 F527 H533 I543 W544 I563A35-F565 HydrophobicContact CB-CD2 3.54Å; A35-F565 HydrophobicContact CB-CE2 4Å; A35-F565 WeakPolarHBondContact O-CA 3.39Å; F37-F565 HydrophobicContact CD1-CZ 4.48Å; F37-F565 HydrophobicContact CD2-CE1 4.18Å; F37-F565 HydrophobicContact CD2-CZ 4.39Å; F37-F565 AromaticContact CE1-CE1 3.96Å; F37-F565 HydrophobicContact CE1-CE1 3.96Å; F37-F565 AromaticContact CE1-CZ 3.85Å; F37-F565 HydrophobicContact CE1-CZ 3.85Å; F37-F565 AromaticContact CE2-CD1 3.75Å; F37-F565 HydrophobicContact CE2-CD1 3.75Å; F37-F565 AromaticContact CE2-CE1 3.21Å; F37-F565 HydrophobicContact CE2-CE1 3.21Å; F37-F565 AromaticContact CE2-CZ 3.75Å; F37-F565 HydrophobicContact CE2-CZ 3.75Å; F37-F565 HydrophobicContact CZ-CD1 4.07Å; F37-F565 AromaticContact CZ-CE1 3.09Å; F37-F565 HydrophobicContact CZ-CE1 3.09Å; F37-F565 AromaticContact CZ-CZ 3.46Å; F37-F565 HydrophobicContact CZ-CZ 3.46Å; F37-F565 VanDerWaalsContact CZ-CZ 3.46Å; A485-F565 WeakPolarHBondContact CA-O 3.38Å; F486-F565 PolarHBondContact N-O 3.29Å; F486-F565 PolarHBondContact O-N 3.04Å; F527-F565 HydrophobicContact CD1-CD1 4.42Å; F527-F565 HydrophobicContact CD2-CD1 4.1Å; F527-F565 AromaticContact CD2-CE1 3.93Å; F527-F565 HydrophobicContact CD2-CE1 3.93Å; F527-F565 HydrophobicContact CE1-CD1 4.14Å; F527-F565 AromaticContact CE2-CD1 3.81Å; F527-F565 HydrophobicContact CE2-CD1 3.81Å; F527-F565 HydrophobicContact CE2-CE1 4.09Å; F527-F565 HydrophobicContact CG-CD1 4.42Å; F527-F565 HydrophobicContact CG-CE1 4.2Å; F527-F565 AromaticContact CZ-CD1 3.83Å; F527-F565 HydrophobicContact CZ-CD1 3.83Å; F527-F565 HydrophobicContact CZ-CE1 4.47Å; H533-F565 AromaticContact CE1-CE1 3.71Å; H533-F565 AromaticContact CE1-CZ 3.84Å; H533-F565 AromaticContact CG-CZ 3.94Å; H533-F565 AromaticContact ND1-CE1 3.57Å; H533-F565 AromaticContact ND1-CZ 3.68Å; I543-F565 HydrophobicContact CD1-CD2 4.1Å; W544-F565 HydrophobicContact CH2-CB 3.64Å; W544-F565 AromaticContact CH2-CD1 3.93Å; W544-F565 HydrophobicContact CH2-CD1 3.93Å; W544-F565 HydrophobicContact CH2-CG 4.06Å; W544-F565 HydrophobicContact CZ2-CB 3.98Å; W544-F565 AromaticContact CZ2-CD1 3.57Å; W544-F565 HydrophobicContact CZ2-CD1 3.57Å; W544-F565 HydrophobicContact CZ2-CE1 4.16Å; W544-F565 AromaticContact CZ2-CG 3.88Å; W544-F565 HydrophobicContact CZ2-CG 3.88Å; I563-F565 PolarHBondContact O-N 3.24Å
566G92.4Very high91Very high0 Ų029.4 Ų29.40%016%0.164CC..EExtended strand (participates in β ladder)trans176-159.5-175.600000115.6A35 D36 F37 R483A35-G566 PolarHBondContact O-N 2.92Å; D36-G566 WeakPolarHBondContact CA-O 3.11Å; F37-G566 PolarHBondContact N-O 3.18Å; R483-G566 PolarHBondContact NH1-O 3.31Å; R483-G566 VanDerWaalsContact NH1-O 3.08Å
567W91.8Very high91.1Very high8 Ų834.6 Ų34.63%0.0318%0.184CC..EExtended strand (participates in β ladder)trans-110.3129.4-168.4-62.1-96.3000112.4F37 R483 L484 I508 M525 F527 F570F37-W567 HydrophobicContact CB-CG 4.26Å; F37-W567 AromaticContact CD2-CD1 3.96Å; F37-W567 AromaticContact CD2-CD2 3.83Å; F37-W567 HydrophobicContact CD2-CD2 3.83Å; F37-W567 AromaticContact CD2-CE2 3.4Å; F37-W567 HydrophobicContact CD2-CG 4.16Å; F37-W567 AromaticContact CD2-CZ2 3.8Å; F37-W567 HydrophobicContact CD2-CZ2 3.8Å; F37-W567 AromaticContact CD2-NE1 3.47Å; F37-W567 HydrophobicContact CE2-CD2 4.42Å; F37-W567 AromaticContact CE2-CE2 3.81Å; F37-W567 HydrophobicContact CE2-CH2 4.23Å; F37-W567 AromaticContact CE2-CZ2 3.69Å; F37-W567 HydrophobicContact CE2-CZ2 3.69Å; F37-W567 AromaticContact CG-NE1 3.6Å; F37-W567 HydrophobicContact CZ-CZ2 4.4Å; R483-W567 WeakPolarHBondContact CA-O 3.42Å; R483-W567 WeakPolarHBondContact CB-O 3.28Å; R483-W567 VanDerWaalsContact CG-O 3.31Å; R483-W567 WeakPolarHBondContact CG-O 3.18Å; L484-W567 PolarHBondContact N-O 2.96Å; L484-W567 PolarHBondContact O-N 3.19Å; I508-W567 HydrophobicContact CD1-CZ3 3.86Å; I508-W567 HydrophobicContact CG1-CZ3 4.36Å; M525-W567 HydrophobicContact CB-CD2 3.71Å; M525-W567 HydrophobicContact CB-CE3 3.61Å; M525-W567 HydrophobicContact CB-CH2 3.31Å; M525-W567 HydrophobicContact CB-CZ2 3.52Å; M525-W567 HydrophobicContact CB-CZ3 3.41Å; M525-W567 VanDerWaalsContact CB-CZ3 3.41Å; M525-W567 HydrophobicContact CG-CD2 3.95Å; M525-W567 HydrophobicContact CG-CE3 4.12Å; M525-W567 HydrophobicContact CG-CG 4.3Å; M525-W567 HydrophobicContact CG-CZ2 4.47Å; M525-W567 HydrophobicContact CG-CZ3 4.39Å; F527-W567 HydrophobicContact CB-CH2 4.39Å; F527-W567 HydrophobicContact CB-CZ2 4.33Å; F527-W567 AromaticContact CD1-CH2 3.47Å; F527-W567 HydrophobicContact CD1-CH2 3.47Å; F527-W567 VanDerWaalsContact CD1-CH2 3.47Å; F527-W567 HydrophobicContact CD1-CZ2 4.11Å; F527-W567 HydrophobicContact CD1-CZ3 4.04Å; F527-W567 HydrophobicContact CE1-CH2 4.25Å; F527-W567 HydrophobicContact CE1-CZ3 4.39Å; F527-W567 HydrophobicContact CG-CH2 4.41Å; W567-F570 HydrophobicContact CB-CD2 4.29Å; W567-F570 HydrophobicContact CE3-CD2 4.07Å; W567-F570 HydrophobicContact CE3-CE2 4.09Å; W567-F570 HydrophobicContact CZ3-CE2 4.41Å
568S88.4Confident91Very high39 Ų3937.1 Ų37.127%0.27319%0.189SC..EExtended strand (participates in β ladder)trans-79-23.6-177.9-70.20000114.1D36 R483D36-S568 PolarHBondContact OD2-OG 3.13Å; R483-S568 PolarHBondContact NH1-OG 3.25Å
569G86.3Confident90.9Very high42 Ų4234.1 Ų34.143%0.43317%0.169SC..EExtended strand (participates in β ladder)trans-118.469.6170.900000110.9
570F91.6Very high90.9Very high6 Ų635.6 Ų35.63%0.02618%0.18CC..EExtended strand (participates in β ladder)trans-74.1-49.6-177.5-164.4-74.8000111.4L482 L484 I508 I510 S523 M525 W567L482-F570 WeakPolarHBondContact O-CB 3.18Å; L482-F570 PolarHBondContact O-N 2.84Å; L484-F570 HydrophobicContact CB-CB 4.29Å; L484-F570 HydrophobicContact CB-CD2 3.67Å; L484-F570 HydrophobicContact CB-CE2 4.13Å; L484-F570 HydrophobicContact CB-CG 3.99Å; L484-F570 HydrophobicContact CD2-CD2 4.29Å; L484-F570 HydrophobicContact CD2-CE1 4.39Å; L484-F570 HydrophobicContact CD2-CE2 3.99Å; L484-F570 HydrophobicContact CD2-CZ 4.06Å; I508-F570 HydrophobicContact CB-CE2 4.13Å; I508-F570 HydrophobicContact CB-CZ 4.27Å; I508-F570 HydrophobicContact CG2-CE2 4.3Å; I508-F570 HydrophobicContact CG2-CZ 4.29Å; I508-F570 WeakPolarHBondContact O-CZ 3.05Å; I510-F570 HydrophobicContact CB-CE1 4.25Å; I510-F570 HydrophobicContact CD1-CD1 3.44Å; I510-F570 VanDerWaalsContact CD1-CD1 3.44Å; I510-F570 HydrophobicContact CD1-CE1 3.58Å; I510-F570 HydrophobicContact CD1-CG 4.45Å; I510-F570 HydrophobicContact CG1-CD1 4.02Å; I510-F570 HydrophobicContact CG1-CE1 3.59Å; I510-F570 HydrophobicContact CG1-CZ 4.42Å; S523-F570 WeakPolarHBondContact O-CE1 3.41Å; S523-F570 PolarHBondContact OG-O 2.85Å; M525-F570 HydrophobicContact CB-CD2 4.29Å; M525-F570 HydrophobicContact CB-CE2 3.61Å; M525-F570 HydrophobicContact CB-CZ 4.1Å; M525-F570 HydrophobicContact CG-CD2 3.69Å; M525-F570 HydrophobicContact CG-CE1 4.39Å; M525-F570 HydrophobicContact CG-CE2 3.36Å; M525-F570 HydrophobicContact CG-CG 4.36Å; M525-F570 HydrophobicContact CG-CZ 3.76Å; W567-F570 HydrophobicContact CB-CD2 4.29Å; W567-F570 HydrophobicContact CE3-CD2 4.07Å; W567-F570 HydrophobicContact CE3-CE2 4.09Å; W567-F570 HydrophobicContact CZ3-CE2 4.41Å
571I91.3Very high90.9Very high8 Ų832.2 Ų32.24%0.04117%0.165CC..EExtended strand (participates in β ladder)trans-151.6145.5173.1-167.8166.2000109.2Y481 L482 I510 M575 L576 F581Y481-I571 WeakPolarHBondContact CA-O 3.21Å; L482-I571 HydrophobicContact CB-CG2 4.32Å; L482-I571 HydrophobicContact CD1-CG2 3.62Å; L482-I571 WeakPolarHBondContact CD1-O 3.31Å; L482-I571 HydrophobicContact CG-CG2 4.49Å; L482-I571 PolarHBondContact N-O 3.29Å; I510-I571 HydrophobicContact CD1-CB 4.4Å; I510-I571 HydrophobicContact CD1-CG2 3.57Å; I571-M575 HydrophobicContact CD1-CB 4.25Å; I571-M575 HydrophobicContact CD1-CG 3.94Å; I571-M575 HydrophobicContact CG1-CB 3.85Å; I571-M575 HydrophobicContact CG1-CG 3.97Å; I571-L576 HydrophobicContact CD1-CD2 4.13Å; I571-L576 HydrophobicContact CG2-CD2 3.84Å; I571-L576 HydrophobicContact CG2-CG 4.11Å; I571-F581 HydrophobicContact CD1-CD1 4.18Å; I571-F581 HydrophobicContact CD1-CD2 3.89Å; I571-F581 HydrophobicContact CD1-CE1 3.95Å; I571-F581 HydrophobicContact CD1-CE2 3.67Å; I571-F581 HydrophobicContact CD1-CG 4.14Å; I571-F581 HydrophobicContact CD1-CZ 3.69Å
572S90.8Very high90.8Very high23 Ų2333.4 Ų33.416%0.16117%0.171CC..EExtended strand (participates in β ladder)trans-79.3151.6178.773.80000111.7Y481 Q574 M575 L576Y481-S572 VanDerWaalsContact CE1-CB 3.46Å; S572-Q574 PolarHBondContact O-N 2.86Å; S572-M575 PolarHBondContact O-N 3.06Å; S572-M575 VanDerWaalsContact O-N 3.09Å; S572-M575 WeakPolarHBondContact OG-CB 3.28Å; S572-M575 PolarHBondContact OG-N 3.32Å; S572-L576 PolarHBondContact O-N 2.77Å
573H90.8Very high90.7Very high39 Ų3933.7 Ų33.718%0.18117%0.172CC..Hα-helixtrans-59-31.2172.7-66.7173.1000112.3P473 H474 G480P473-H573 PolarHBondContact O-NE2 3.48Å; H474-H573 AromaticContact ND1-CE1 3.44Å; H474-H573 PolarHBondContact ND1-CE1 2.74Å; G480-H573 PolarHBondContact O-N 3.15Å
574Q88.4Confident90.5Very high104 Ų10436.2 Ų36.249%0.48619%0.186SC..Hα-helixtrans-67.9-44.2175.2-177.8173.69.700111.1S237 S572 K577S237-Q574 PolarHBondContact OG-NE2 3.02Å; S572-Q574 PolarHBondContact O-N 2.86Å; Q574-K577 PolarHBondContact O-N 3.07Å
575M87.5Confident90.6Very high31 Ų3137.9 Ų37.915%0.15319%0.194CC..Hα-helixtrans-67.6-37.2-179.5-170.66277.100111.9L243 I571 S572 K577 R578 F581L243-M575 HydrophobicContact CD1-CE 4.35Å; L243-M575 HydrophobicContact CD1-CG 4.2Å; L243-M575 HydrophobicContact CD1-SD 4.07Å; I571-M575 HydrophobicContact CD1-CB 4.25Å; I571-M575 HydrophobicContact CD1-CG 3.94Å; I571-M575 HydrophobicContact CG1-CB 3.85Å; I571-M575 HydrophobicContact CG1-CG 3.97Å; S572-M575 PolarHBondContact O-N 3.06Å; S572-M575 VanDerWaalsContact O-N 3.09Å; S572-M575 WeakPolarHBondContact OG-CB 3.28Å; S572-M575 PolarHBondContact OG-N 3.32Å; M575-K577 PolarHBondContact O-N 3.14Å; M575-K577 VanDerWaalsContact O-N 3.11Å; M575-R578 PolarHBondContact O-N 2.77Å; M575-R578 VanDerWaalsContact O-N 3.08Å; M575-R578 HydrophobicContact SD-CB 4.46Å; M575-F581 HydrophobicContact CG-CE2 3.96Å; M575-F581 WeakPolarHBondContact O-CD2 3.34Å
576L89.9Confident90.6Very high1 Ų137.5 Ų37.51%0.00519%0.193CC..Hα-helixtrans-53-33.2174.1-81.6-168.2000113.8F441 L482 I571 S572 F581 L582 L587F441-L576 HydrophobicContact CD1-CD1 4.34Å; F441-L576 HydrophobicContact CE1-CD1 3.81Å; L482-L576 HydrophobicContact CD1-CD1 3.24Å; L482-L576 HydrophobicContact CD1-CD2 4.37Å; L482-L576 HydrophobicContact CD1-CG 3.69Å; L482-L576 HydrophobicContact CD2-CD1 3.93Å; L482-L576 HydrophobicContact CG-CD1 4.22Å; I571-L576 HydrophobicContact CD1-CD2 4.13Å; I571-L576 HydrophobicContact CG2-CD2 3.84Å; I571-L576 HydrophobicContact CG2-CG 4.11Å; S572-L576 PolarHBondContact O-N 2.77Å; L576-F581 HydrophobicContact CD2-CB 3.82Å; L576-F581 HydrophobicContact CD2-CG 4.34Å; L576-L582 HydrophobicContact CB-CD1 4.24Å; L576-L582 HydrophobicContact CB-CG 4.35Å; L576-L582 HydrophobicContact CD1-CD1 4.31Å; L576-L587 HydrophobicContact CD2-CD1 3.94Å
577K87.5Confident90.9Very high158 Ų15837.5 Ų37.569%0.68719%0.193SC*.THydrogen-bonded Turntrans-90.3-4.5-175.9-65-179.6-179.4-176.20113.9Q574 M575Q574-K577 PolarHBondContact O-N 3.07Å; M575-K577 PolarHBondContact O-N 3.14Å; M575-K577 VanDerWaalsContact O-N 3.11Å
578R84.4Confident91.2Very high82 Ų8237.3 Ų37.331%0.30919%0.193SC..THydrogen-bonded Turntrans-93.4-42.4-172.3-83.4-176.3160.6170.6-6.1114E234 S237 M575E234-R578 PolarHBondContact O-NH2 2.82Å; S237-R578 PolarHBondContact O-NH1 2.96Å; S237-R578 PolarHBondContact OG-NH1 3.08Å; S237-R578 PolarHBondContact OG-NH2 2.9Å; M575-R578 PolarHBondContact O-N 2.77Å; M575-R578 VanDerWaalsContact O-N 3.08Å; M575-R578 HydrophobicContact SD-CB 4.46Å
579R89.5Confident91.7Very high54 Ų5435.4 Ų35.420%0.20418%0.18CC..SBendtrans-107.9-169.4177.9-54-167.171.888.1-5.9109.9E209 D512 N519 M521 F581E209-R579 IonicContact OE1-NH1 3.89Å; E209-R579 PolarHBondContact OE1-NH1 2.85Å; E209-R579 IonicContact OE2-NH1 2.74Å; E209-R579 PolarHBondContact OE2-NH1 3.13Å; D512-R579 IonicContact OD2-CZ 2.89Å; D512-R579 IonicContact OD2-NE 3.21Å; D512-R579 PolarHBondContact OD2-NE 3.02Å; D512-R579 IonicContact OD2-NH2 3.95Å; N519-R579 PolarHBondContact O-NH2 2.93Å; M521-R579 PolarHBondContact SD-NH1 3.28Å; M521-R579 VanDerWaalsContact SD-NH1 3.42Å; R579-F581 HydrophobicContact CB-CD2 3.93Å; R579-F581 HydrophobicContact CB-CE2 3.98Å; R579-F581 HydrophobicContact CG-CE2 4.26Å; R579-F581 PolarHBondContact O-N 2.92Å
580S93.9Very high92.2Very high33 Ų3334.4 Ų34.423%0.23116%0.163CC..THydrogen-bonded Turntrans-82.531.8179.8-61.40000112.4D512 Q513 L582D512-S580 WeakPolarHBondContact OD1-CA 3.26Å; D512-S580 WeakPolarHBondContact OD1-CB 3Å; D512-S580 PolarHBondContact OD1-N 3.22Å; Q513-S580 VanDerWaalsContact C-CB 3.5Å; Q513-S580 WeakPolarHBondContact CB-O 3.4Å; Q513-S580 VanDerWaalsContact CG-O 3.29Å; Q513-S580 WeakPolarHBondContact CG-O 3.42Å; Q513-S580 PolarHBondContact N-O 3.43Å; S580-L582 VanDerWaalsContact C-N 3.33Å
581F95.9Very high92.5Very high0 Ų034.1 Ų34.10%016%0.162CC..THydrogen-bonded Turntrans-64.9-40.5174.1-70-64.9000111.5L243 I510 D512 Q513 M521 I571 M575 L576 R579L243-F581 HydrophobicContact CD1-CE2 4.32Å; L243-F581 HydrophobicContact CD1-CZ 4.08Å; L243-F581 HydrophobicContact CD2-CZ 4.48Å; I510-F581 HydrophobicContact CG2-CD1 3.8Å; I510-F581 HydrophobicContact CG2-CE1 4.39Å; D512-F581 HydrophobicContact CB-CD1 4.23Å; D512-F581 HydrophobicContact CB-CE1 3.92Å; D512-F581 HydrophobicContact CB-CZ 4.31Å; Q513-F581 PolarHBondContact NE2-O 2.96Å; M521-F581 VanDerWaalsContact O-CZ 3.31Å; M521-F581 WeakPolarHBondContact O-CZ 3.27Å; I571-F581 HydrophobicContact CD1-CD1 4.18Å; I571-F581 HydrophobicContact CD1-CD2 3.89Å; I571-F581 HydrophobicContact CD1-CE1 3.95Å; I571-F581 HydrophobicContact CD1-CE2 3.67Å; I571-F581 HydrophobicContact CD1-CG 4.14Å; I571-F581 HydrophobicContact CD1-CZ 3.69Å; M575-F581 HydrophobicContact CG-CE2 3.96Å; M575-F581 WeakPolarHBondContact O-CD2 3.34Å; L576-F581 HydrophobicContact CD2-CB 3.82Å; L576-F581 HydrophobicContact CD2-CG 4.34Å; R579-F581 HydrophobicContact CB-CD2 3.93Å; R579-F581 HydrophobicContact CB-CE2 3.98Å; R579-F581 HydrophobicContact CG-CE2 4.26Å; R579-F581 PolarHBondContact O-N 2.92Å
582L94.1Very high92.9Very high35 Ų3535.5 Ų35.518%0.18317%0.169CC..EExtended strand (participates in β ladder)trans-107.594.3170.4-59.6-177000109F441 L576 S580 L587F441-L582 HydrophobicContact CB-CD2 3.9Å; F441-L582 HydrophobicContact CD1-CD1 4.09Å; F441-L582 HydrophobicContact CD1-CD2 3.62Å; F441-L582 HydrophobicContact CG-CD2 3.97Å; L576-L582 HydrophobicContact CB-CD1 4.24Å; L576-L582 HydrophobicContact CB-CG 4.35Å; L576-L582 HydrophobicContact CD1-CD1 4.31Å; S580-L582 VanDerWaalsContact C-N 3.33Å; L582-L587 HydrophobicContact CD2-CB 3.77Å; L582-L587 HydrophobicContact CD2-CD1 3.79Å; L582-L587 HydrophobicContact CD2-CG 4.35Å
583K91.9Very high93.2Very high12 Ų1234.4 Ų34.45%0.05216%0.162CC..EExtended strand (participates in β ladder)trans-113.3128.7176.8-168.2170.3-170.5-166.50107.8H302 T303 L305 D423 Q513 D585 D586H302-K583 WeakPolarHBondContact O-CE 3.48Å; H302-K583 PolarHBondContact O-NZ 3.13Å; T303-K583 VanDerWaalsContact O-CE 3.32Å; T303-K583 WeakPolarHBondContact O-CE 3.33Å; T303-K583 PolarHBondContact O-NZ 3.09Å; L305-K583 HydrophobicContact CD1-CG 3.5Å; L305-K583 VanDerWaalsContact CD1-CG 3.5Å; L305-K583 HydrophobicContact CG-CG 4.25Å; D423-K583 IonicContact OD2-NZ 3.97Å; D423-K583 PolarHBondContact OD2-NZ 3.17Å; Q513-K583 HydrophobicContact CB-CB 3.89Å; Q513-K583 HydrophobicContact CB-CD 3.7Å; Q513-K583 HydrophobicContact CB-CG 4.42Å; Q513-K583 HydrophobicContact CG-CB 4.3Å; Q513-K583 WeakPolarHBondContact O-CD 3.4Å; Q513-K583 PolarHBondContact O-NZ 2.9Å; K583-D585 PolarHBondContact O-N 3.07Å; K583-D586 PolarHBondContact N-O 3.37Å; K583-D586 WeakPolarHBondContact O-CB 3.13Å; K583-D586 PolarHBondContact O-N 3Å
584N89.3Confident93.5Very high64 Ų6435.7 Ų35.734%0.34217%0.168SC..THydrogen-bonded Turntrans5827.2-169.1-170.255000113.1L305 D586L305-N584 HydrophobicContact CD1-CB 3.9Å; L305-N584 HydrophobicContact CD2-CB 4.02Å; N584-D586 PolarHBondContact ND2-OD2 3.49Å; N584-D586 PolarHBondContact O-N 3.35Å
585D92.8Very high93.9Very high42 Ų4233.6 Ų33.623%0.22516%0.16CC..THydrogen-bonded Turntrans57.519.8-169.3-155.932.2000114.3N440 F441 S442 K583N440-D585 WeakPolarHBondContact CA-OD2 3.36Å; N440-D585 PolarHBondContact N-O 2.79Å; N440-D585 VanDerWaalsContact N-O 3.15Å; F441-D585 WeakPolarHBondContact CB-O 3.46Å; F441-D585 PolarHBondContact N-O 3.12Å; F441-D585 PolarHBondContact N-OD2 2.91Å; S442-D585 VanDerWaalsContact CB-OD1 3.23Å; S442-D585 WeakPolarHBondContact CB-OD1 3.47Å; S442-D585 VanDerWaalsContact CB-OD2 3.32Å; S442-D585 WeakPolarHBondContact CB-OD2 2.95Å; S442-D585 PolarHBondContact N-OD1 3.01Å; S442-D585 PolarHBondContact N-OD2 3.09Å; S442-D585 VanDerWaalsContact N-OD2 3.08Å; S442-D585 PolarHBondContact OG-OD1 3.04Å; K583-D585 PolarHBondContact O-N 3.07Å
586D95Very high94.3Very high6 Ų632.8 Ų32.83%0.03216%0.156CC..EExtended strand (participates in β ladder)trans-97.3130.7176.9-59.6-38.4000109.9T437 Q439 Q513 K583 N584T437-D586 HydrophobicContact CG2-CB 4.12Å; Q439-D586 VanDerWaalsContact CA-OD1 3.27Å; Q439-D586 WeakPolarHBondContact CA-OD1 3.41Å; Q439-D586 WeakPolarHBondContact CB-OD1 3.38Å; Q439-D586 WeakPolarHBondContact CG-OD1 3.35Å; Q513-D586 PolarHBondContact NE2-O 3.49Å; K583-D586 PolarHBondContact N-O 3.37Å; K583-D586 WeakPolarHBondContact O-CB 3.13Å; K583-D586 PolarHBondContact O-N 3Å; N584-D586 PolarHBondContact ND2-OD2 3.49Å; N584-D586 PolarHBondContact O-N 3.35Å
587L97.4Very high94.5Very high0 Ų034.9 Ų34.90%017%0.169CC..EExtended strand (participates in β ladder)trans-102.7117.8170.1-178.171.9000109T437 V438 F441 L471 L482 I510 L576 L582 M589T437-L587 WeakPolarHBondContact CA-O 3.18Å; V438-L587 HydrophobicContact CB-CB 4.43Å; V438-L587 PolarHBondContact N-O 3.08Å; V438-L587 PolarHBondContact O-N 2.71Å; F441-L587 HydrophobicContact CB-CB 4.19Å; F441-L587 HydrophobicContact CD1-CB 4.45Å; F441-L587 HydrophobicContact CD1-CD2 4.36Å; F441-L587 HydrophobicContact CD2-CB 3.98Å; F441-L587 HydrophobicContact CD2-CD2 3.88Å; F441-L587 HydrophobicContact CE1-CD2 4.12Å; F441-L587 HydrophobicContact CE2-CD2 3.65Å; F441-L587 HydrophobicContact CG-CB 3.91Å; F441-L587 HydrophobicContact CG-CD2 4.25Å; F441-L587 HydrophobicContact CZ-CD2 3.78Å; L471-L587 HydrophobicContact CD2-CD2 3.96Å; L482-L587 HydrophobicContact CD2-CD2 4.45Å; I510-L587 HydrophobicContact CG2-CD1 3.61Å; L576-L587 HydrophobicContact CD2-CD1 3.94Å; L582-L587 HydrophobicContact CD2-CB 3.77Å; L582-L587 HydrophobicContact CD2-CD1 3.79Å; L582-L587 HydrophobicContact CD2-CG 4.35Å; L587-M589 HydrophobicContact CD2-CE 4.17Å; L587-M589 HydrophobicContact CD2-SD 4.4Å
588I98.3Very high94.8Very high4 Ų433.5 Ų33.52%0.02117%0.165CC..EExtended strand (participates in β ladder)trans-107.7126.3-178.8-57.2179000110.1F347 I390 V435 T437 L511 Q513 F590F347-I588 HydrophobicContact CE1-CD1 3.86Å; F347-I588 HydrophobicContact CZ-CD1 4.02Å; I390-I588 HydrophobicContact CB-CD1 4.32Å; I390-I588 HydrophobicContact CG2-CD1 4.02Å; I390-I588 HydrophobicContact CG2-CG2 4.21Å; V435-I588 HydrophobicContact CG1-CG2 4.25Å; T437-I588 HydrophobicContact CG2-CG1 4.06Å; L511-I588 HydrophobicContact CB-CB 4.22Å; L511-I588 HydrophobicContact CB-CG2 4.34Å; L511-I588 HydrophobicContact CD2-CB 4.24Å; L511-I588 HydrophobicContact CD2-CD1 4.4Å; L511-I588 HydrophobicContact CD2-CG2 4.06Å; L511-I588 PolarHBondContact N-O 3.37Å; Q513-I588 HydrophobicContact CG-CD1 4.34Å; Q513-I588 VanDerWaalsContact OE1-CD1 3.23Å; I588-F590 HydrophobicContact CG2-CD1 4.12Å; I588-F590 HydrophobicContact CG2-CE1 3.5Å; I588-F590 VanDerWaalsContact CG2-CE1 3.5Å; I588-F590 HydrophobicContact CG2-CZ 4.23Å
589M98.4Very high95.2Very high0 Ų030.6 Ų30.60%016%0.155CC..EExtended strand (participates in β ladder)trans-120.4136.4177.9-70165.8-74.400111.1V435 W436 V438 L469 L471 L484 T509 I510 L587V435-M589 WeakPolarHBondContact CA-O 3.42Å; W436-M589 HydrophobicContact CD2-CE 3.64Å; W436-M589 HydrophobicContact CE3-CE 3.22Å; W436-M589 HydrophobicContact CE3-SD 3.98Å; W436-M589 HydrophobicContact CG-CE 4.27Å; W436-M589 HydrophobicContact CH2-CE 4.27Å; W436-M589 HydrophobicContact CZ3-CE 3.6Å; W436-M589 HydrophobicContact CZ3-SD 4.19Å; W436-M589 PolarHBondContact N-O 2.85Å; W436-M589 PolarHBondContact O-N 3.23Å; V438-M589 HydrophobicContact CG2-CE 3.65Å; L469-M589 HydrophobicContact CD1-CB 4.21Å; L471-M589 HydrophobicContact CD1-SD 4.43Å; L471-M589 HydrophobicContact CD2-CE 4.01Å; L471-M589 HydrophobicContact CD2-SD 4.42Å; L484-M589 HydrophobicContact CD1-SD 3.62Å; L484-M589 HydrophobicContact CD2-CG 4.29Å; L484-M589 HydrophobicContact CD2-SD 3.84Å; L484-M589 HydrophobicContact CG-SD 4.43Å; T509-M589 CarbonylContact O-C 3.54Å; T509-M589 VanDerWaalsContact O-CA 3.25Å; T509-M589 WeakPolarHBondContact O-CA 3.48Å; I510-M589 HydrophobicContact CG1-CG 3.94Å; L587-M589 HydrophobicContact CD2-CE 4.17Å; L587-M589 HydrophobicContact CD2-SD 4.4Å
590F98.3Very high95.1Very high21 Ų2131.1 Ų31.19%0.09217%0.167CC..EExtended strand (participates in β ladder)trans-108.5149.8170.7-54.5-26.2000110.6I390 H392 P432 G434 V435 I508 T509 L511 I588I390-F590 HydrophobicContact CD1-CE1 4.28Å; I390-F590 HydrophobicContact CD1-CZ 3.88Å; H392-F590 AromaticContact CE1-CE1 3.55Å; H392-F590 AromaticContact CE1-CZ 3.48Å; H392-F590 VanDerWaalsContact CE1-CZ 3.48Å; H392-F590 WeakPolarHBondContact CE1-CZ 3.47Å; H392-F590 AromaticContact NE2-CZ 3.5Å; P432-F590 HydrophobicContact CB-CB 3.87Å; P432-F590 HydrophobicContact CB-CD1 4.4Å; P432-F590 HydrophobicContact CB-CD2 4.33Å; P432-F590 HydrophobicContact CB-CG 3.98Å; P432-F590 HydrophobicContact CG-CD1 4.24Å; P432-F590 HydrophobicContact CG-CD2 4.28Å; P432-F590 HydrophobicContact CG-CE1 4.5Å; P432-F590 HydrophobicContact CG-CG 4.13Å; G434-F590 CarbonylContact O-C 3.57Å; G434-F590 WeakPolarHBondContact O-CA 3.29Å; V435-F590 HydrophobicContact CB-CD1 4.26Å; V435-F590 HydrophobicContact CB-CE1 4.47Å; V435-F590 HydrophobicContact CG1-CD1 3.94Å; V435-F590 HydrophobicContact CG1-CE1 3.79Å; V435-F590 HydrophobicContact CG2-CD1 3.81Å; V435-F590 HydrophobicContact CG2-CE1 4Å; I508-F590 WeakPolarHBondContact CA-O 3.45Å; T509-F590 PolarHBondContact N-O 2.97Å; T509-F590 PolarHBondContact O-N 2.83Å; L511-F590 HydrophobicContact CB-CE2 4.44Å; L511-F590 HydrophobicContact CB-CZ 4.42Å; L511-F590 HydrophobicContact CD1-CE2 3.98Å; L511-F590 HydrophobicContact CD1-CZ 4.3Å; L511-F590 HydrophobicContact CD2-CE1 4.42Å; L511-F590 HydrophobicContact CD2-CE2 4.24Å; L511-F590 HydrophobicContact CD2-CZ 3.71Å; L511-F590 HydrophobicContact CG-CE2 4.45Å; L511-F590 HydrophobicContact CG-CZ 4.37Å; I588-F590 HydrophobicContact CG2-CD1 4.12Å; I588-F590 HydrophobicContact CG2-CE1 3.5Å; I588-F590 VanDerWaalsContact CG2-CE1 3.5Å; I588-F590 HydrophobicContact CG2-CZ 4.23Å
591V98.1Very high94.4Very high0 Ų037.2 Ų37.20%019%0.192CC..EExtended strand (participates in β ladder)trans-141.7128.4172.851.80000111G434 F459 F467 L469 F486 V506 I507G434-V591 PolarHBondContact N-O 3.45Å; G434-V591 PolarHBondContact O-N 3.01Å; F459-V591 HydrophobicContact CD2-CG1 4.01Å; F459-V591 HydrophobicContact CE2-CG1 4.11Å; F467-V591 HydrophobicContact CD2-CG1 4.49Å; F467-V591 HydrophobicContact CD2-CG2 4.18Å; F467-V591 HydrophobicContact CE2-CB 4.29Å; F467-V591 HydrophobicContact CE2-CG1 3.71Å; F467-V591 HydrophobicContact CE2-CG2 3.69Å; L469-V591 HydrophobicContact CD1-CB 4.04Å; L469-V591 HydrophobicContact CD1-CG1 4.05Å; L469-V591 HydrophobicContact CD2-CB 4.03Å; L469-V591 HydrophobicContact CD2-CG1 4.4Å; L469-V591 HydrophobicContact CD2-CG2 3.92Å; L469-V591 HydrophobicContact CG-CB 4.16Å; L469-V591 HydrophobicContact CG-CG1 4.05Å; L469-V591 HydrophobicContact CG-CG2 4.49Å; F486-V591 HydrophobicContact CD2-CG2 4.01Å; F486-V591 HydrophobicContact CE2-CG2 4.11Å; V506-V591 HydrophobicContact CG1-CG2 4.44Å; I507-V591 CarbonylContact O-C 3.57Å; I507-V591 VanDerWaalsContact O-CA 3.29Å; I507-V591 WeakPolarHBondContact O-CA 2.97Å
592D97.8Very high93Very high36 Ų3638.4 Ų38.419%0.19320%0.2CC..EExtended strand (participates in β ladder)trans-112.9147.5172.1-62.5-54.9000110.1P432 T433 V506 I507P432-D592 VanDerWaalsContact CA-OD1 3.23Å; P432-D592 WeakPolarHBondContact CA-OD1 3.41Å; T433-D592 PolarHBondContact N-OD1 2.75Å; V506-D592 VanDerWaalsContact CA-O 3.29Å; V506-D592 WeakPolarHBondContact CA-O 3.05Å; I507-D592 HydrophobicContact CB-CB 4.25Å; I507-D592 PolarHBondContact N-O 2.54Å; I507-D592 VanDerWaalsContact N-O 3.08Å; I507-D592 PolarHBondContact O-N 3.44Å
593F97.6Very high91.5Very high0 Ų043.3 Ų43.30%022%0.222CC..EExtended strand (participates in β ladder)trans-147.885.5-179.3-175.6-135.4000111N461 Y465 F467 F486 V501 R504 Q505 V506 T529N461-F593 HydrophobicContact CB-CB 4.38Å; N461-F593 HydrophobicContact CB-CD1 4.18Å; N461-F593 WeakPolarHBondContact CB-O 3.37Å; N461-F593 PolarHBondContact ND2-O 2.63Å; Y465-F593 HydrophobicContact CD2-CE1 4.44Å; Y465-F593 HydrophobicContact CG-CE1 4.2Å; F467-F593 HydrophobicContact CD1-CB 4.27Å; F467-F593 AromaticContact CD1-CD1 3.85Å; F467-F593 HydrophobicContact CD1-CD1 3.85Å; F467-F593 HydrophobicContact CD1-CG 4.47Å; F467-F593 HydrophobicContact CE1-CB 3.98Å; F467-F593 HydrophobicContact CE1-CD1 4.25Å; F467-F593 HydrophobicContact CE2-CB 4.39Å; F467-F593 HydrophobicContact CG-CD1 4.32Å; F467-F593 HydrophobicContact CZ-CB 4.04Å; F486-F593 HydrophobicContact CE1-CE2 4.34Å; F486-F593 HydrophobicContact CE1-CZ 4.49Å; F486-F593 HydrophobicContact CE2-CB 4.38Å; F486-F593 HydrophobicContact CE2-CD2 4.47Å; F486-F593 HydrophobicContact CE2-CG 4.32Å; F486-F593 HydrophobicContact CZ-CB 4.42Å; F486-F593 HydrophobicContact CZ-CD1 4.06Å; F486-F593 AromaticContact CZ-CD2 3.88Å; F486-F593 HydrophobicContact CZ-CD2 3.88Å; F486-F593 HydrophobicContact CZ-CE1 4.23Å; F486-F593 HydrophobicContact CZ-CE2 4.02Å; F486-F593 AromaticContact CZ-CG 3.87Å; F486-F593 HydrophobicContact CZ-CG 3.87Å; F486-F593 HydrophobicContact CZ-CZ 4.2Å; V501-F593 HydrophobicContact CG1-CZ 3.8Å; R504-F593 HydrophobicContact CB-CD2 3.7Å; R504-F593 HydrophobicContact CB-CE2 3.2Å; R504-F593 HydrophobicContact CB-CZ 3.73Å; R504-F593 HydrophobicContact CG-CE2 4.06Å; R504-F593 HydrophobicContact CG-CZ 4.15Å; Q505-F593 WeakPolarHBondContact O-CA 3.02Å; V506-F593 HydrophobicContact CG2-CD2 3.44Å; V506-F593 VanDerWaalsContact CG2-CD2 3.44Å; V506-F593 HydrophobicContact CG2-CE2 3.78Å; V506-F593 HydrophobicContact CG2-CG 4.44Å; T529-F593 HydrophobicContact CG2-CE2 3.79Å; T529-F593 HydrophobicContact CG2-CZ 4.29Å
594E96.8Very high90Very high67 Ų6744.8 Ų44.831%0.31323%0.232SC..EExtended strand (participates in β ladder)trans-125148-167-61.2-58.6145.600112.9T433 S462 R504 Q505 I596T433-E594 PolarHBondContact OG1-OE1 2.82Å; T433-E594 VanDerWaalsContact OG1-OE1 3.08Å; S462-E594 PolarHBondContact OG-OE2 3.25Å; R504-E594 CarbonylContact C-O 3.54Å; R504-E594 VanDerWaalsContact CA-O 3.23Å; R504-E594 WeakPolarHBondContact CA-O 3.34Å; Q505-E594 PolarHBondContact N-O 3.43Å; Q505-E594 PolarHBondContact O-N 3.11Å; Q505-E594 VanDerWaalsContact O-N 3.08Å; E594-I596 PolarHBondContact O-N 2.95Å
595D96.9Very high88.4Confident59 Ų5947.1 Ų47.132%0.31625%0.25SS..EExtended strand (participates in β ladder)trans-72.4123.1177.7178.629.5000111.9R504 T597R504-D595 HydrophobicContact CG-CB 4.39Å; D595-T597 WeakPolarHBondContact OD1-CB 3.47Å; D595-T597 PolarHBondContact OD1-N 2.91Å; D595-T597 PolarHBondContact OD1-OG1 2.99Å
596I96.3Very high86.4Confident14 Ų1447.3 Ų47.37%0.07225%0.253CS..  trans-117.217.2175.862.4160.8000112.7L89 N503 Q505 T528 E594 H598 L599L89-I596 HydrophobicContact CD1-CD1 4.19Å; L89-I596 HydrophobicContact CD1-CG1 4.39Å; L89-I596 HydrophobicContact CD2-CD1 4.35Å; L89-I596 HydrophobicContact CD2-CG1 4.18Å; L89-I596 HydrophobicContact CG-CD1 3.69Å; L89-I596 HydrophobicContact CG-CG1 4.01Å; L89-I596 WeakPolarHBondContact O-CD1 3.37Å; N503-I596 WeakPolarHBondContact O-CG1 3.35Å; N503-I596 PolarHBondContact O-N 2.87Å; Q505-I596 HydrophobicContact CB-CD1 3.76Å; Q505-I596 HydrophobicContact CB-CG1 4.01Å; Q505-I596 HydrophobicContact CB-CG2 4.04Å; Q505-I596 HydrophobicContact CG-CD1 4.42Å; T528-I596 HydrophobicContact CG2-CD1 4.22Å; T528-I596 HydrophobicContact CG2-CG1 4.4Å; E594-I596 PolarHBondContact O-N 2.95Å; I596-H598 PolarHBondContact O-N 2.92Å; I596-L599 HydrophobicContact CB-CD1 4.03Å; I596-L599 HydrophobicContact CB-CG 4.41Å; I596-L599 HydrophobicContact CG2-CD1 4.42Å; I596-L599 WeakPolarHBondContact O-CB 3.45Å; I596-L599 PolarHBondContact O-N 3.07Å
597T95.3Very high84Confident46 Ų4656.9 Ų56.928%0.28229%0.294SS..G310 helixtrans-52.6-33.1-180-61.30000112.7N503 D595 L599 S600N503-T597 WeakPolarHBondContact CB-OG1 3.3Å; N503-T597 PolarHBondContact ND2-OG1 2.91Å; D595-T597 WeakPolarHBondContact OD1-CB 3.47Å; D595-T597 PolarHBondContact OD1-N 2.91Å; D595-T597 PolarHBondContact OD1-OG1 2.99Å; T597-L599 PolarHBondContact O-N 3.49Å; T597-S600 VanDerWaalsContact O-CB 3.23Å; T597-S600 WeakPolarHBondContact O-CB 3.21Å; T597-S600 PolarHBondContact O-N 2.85Å; T597-S600 PolarHBondContact O-OG 3.07Å
598H92.9Very high81.3Confident128 Ų12860.6 Ų60.659%0.59333%0.332SS*.G310 helixtrans-59.3-26.9177.666.3-84.1000113.7I596 S600I596-H598 PolarHBondContact O-N 2.92Å; H598-S600 PolarHBondContact O-N 3.11Å
599L92.9Very high78.3Confident21 Ų2169.2 Ų69.211%0.1137%0.369CS..G310 helixtrans-76.1-9.5177.2-57.8-179.5000113.4L89 K92 L96 I596 T597 Q601L89-L599 HydrophobicContact CD1-CB 3.74Å; K92-L599 HydrophobicContact CB-CB 4.33Å; K92-L599 HydrophobicContact CB-CD1 4.18Å; K92-L599 HydrophobicContact CD-CB 4.23Å; K92-L599 WeakPolarHBondContact CD-O 3.44Å; K92-L599 PolarHBondContact NZ-O 2.98Å; L96-L599 HydrophobicContact CD1-CD1 3.77Å; L96-L599 HydrophobicContact CD1-CD2 3.77Å; L96-L599 HydrophobicContact CD1-CG 4.44Å; I596-L599 HydrophobicContact CB-CD1 4.03Å; I596-L599 HydrophobicContact CB-CG 4.41Å; I596-L599 HydrophobicContact CG2-CD1 4.42Å; I596-L599 WeakPolarHBondContact O-CB 3.45Å; I596-L599 PolarHBondContact O-N 3.07Å; T597-L599 PolarHBondContact O-N 3.49Å; L599-Q601 PolarHBondContact O-N 3.27Å
600S87.5Confident75.2Confident66 Ų6681.1 Ų81.146%0.46242%0.415SS..G310 helixtrans-62.2-31.2175.564.50000112.1T597 H598T597-S600 VanDerWaalsContact O-CB 3.23Å; T597-S600 WeakPolarHBondContact O-CB 3.21Å; T597-S600 PolarHBondContact O-N 2.85Å; T597-S600 PolarHBondContact O-OG 3.07Å; H598-S600 PolarHBondContact O-N 3.11Å
601Q78.9Confident72.3Confident160 Ų16085.8 Ų85.875%0.74844%0.44SS*.SBendtrans-93.6124.8175.2-61.7179.14.800108.7L599L599-Q601 PolarHBondContact O-N 3.27Å
602T67Low69.1Low26 Ų2689 Ų8916%0.1646%0.462CS..  trans-76.514117554.90000110.8L83 D85 V604L83-T602 WeakPolarHBondContact O-CG2 3.15Å; D85-T602 HydrophobicContact CB-CG2 4.24Å; D85-T602 VanDerWaalsContact CG-OG1 3.28Å; D85-T602 VanDerWaalsContact OD1-CB 3.29Å; D85-T602 WeakPolarHBondContact OD1-CB 3.23Å; D85-T602 WeakPolarHBondContact OD1-CG2 3.39Å; D85-T602 PolarHBondContact OD1-OG1 3.29Å; D85-T602 PolarHBondContact OD2-OG1 2.71Å; T602-V604 PolarHBondContact O-N 2.78Å; T602-V604 PolarHBondContact OG1-O 3.29Å
603E61.8Low66.2Low138 Ų13892.2 Ų92.265%0.64549%0.485SS*.SBendtrans-67.1-25178.7-63179.9163.300111.6P112P112-E603 VanDerWaalsContact CB-OE2 3.25Å; P112-E603 WeakPolarHBondContact CB-OE2 3.47Å; P112-E603 WeakPolarHBondContact CG-OE2 3.4Å
604V60.5Low63Low43 Ų43100.1 Ų100.126%0.26152%0.522SS..SBendtrans-128.3112.9179.5-174.30000109.9I82 Y113 T602 T606I82-V604 HydrophobicContact CD1-CB 4.46Å; I82-V604 HydrophobicContact CD1-CG1 4.32Å; Y113-V604 HydrophobicContact CD1-CG2 4.3Å; T602-V604 PolarHBondContact O-N 2.78Å; T602-V604 PolarHBondContact OG1-O 3.29Å; V604-T606 PolarHBondContact O-N 2.86Å; V604-T606 VanDerWaalsContact O-N 3.1Å
605P55.9Low59.8Low113 Ų113100.2 Ų100.273%0.73453%0.53SS*.  trans-61.6114.3177.1-22.832.7000111.3
606T50.7Low57Low46 Ų46103.2 Ų103.228%0.28255%0.545SS..  trans-82.6131.2175.862.40000109.9I82 A84 D85 V604 G608I82-T606 HydrophobicContact CG2-CG2 4.23Å; A84-T606 HydrophobicContact CB-CG2 4.36Å; D85-T606 PolarHBondContact OD2-OG1 3Å; V604-T606 PolarHBondContact O-N 2.86Å; V604-T606 VanDerWaalsContact O-N 3.1Å; T606-G608 PolarHBondContact O-N 2.89Å
607K45.9Very low54Low207 Ų207108.7 Ų108.790%0.957%0.573SS**  trans-70.798.4171-76.7-177.4-178.4174.10107.8K609K607-K609 VanDerWaalsContact C-N 3.32Å; K607-K609 PolarHBondContact O-N 3.17Å
608G39.8Very low50.9Low77 Ų77113.7 Ų113.779%0.79460%0.598SS**  trans-5887.1179.100000112.9T606T606-G608 PolarHBondContact O-N 2.89Å
609K34.7Very low47.9Very low185 Ų185117.6 Ų117.680%0.80462%0.616SS**  trans-88.6101.5154.5-84.7-173.5176.1-178.90106.5K607 L611K607-K609 VanDerWaalsContact C-N 3.32Å; K607-K609 PolarHBondContact O-N 3.17Å; K609-L611 VanDerWaalsContact C-N 3.29Å; K609-L611 PolarHBondContact O-N 3.18Å
610R33.3Very low45.2Very low251 Ų251119.6 Ų119.695%0.94764%0.642SS**  trans-58.496162.5-130.2-177.5-173.1-165.91.6106.8S612R610-S612 PolarHBondContact O-N 2.78Å
611L37.8Very low42.3Very low119 Ų119125.3 Ų125.362%0.62366%0.662SS**  trans-72122.4168.5-74.4166.7000106.8K609K609-L611 VanDerWaalsContact C-N 3.29Å; K609-L611 PolarHBondContact O-N 3.18Å
612S30.4Very low39.9Very low66 Ų66126.7 Ų126.746%0.46267%0.668SS.*  trans-73.4153.2174.167.10000109.5R610 Q614 S615R610-S612 PolarHBondContact O-N 2.78Å; S612-Q614 PolarHBondContact O-N 2.03Å; S612-S615 PolarHBondContact O-N 3.33Å; S612-S615 VanDerWaalsContact O-N 3.13Å; S612-S615 PolarHBondContact O-OG 3.11Å
613P37.1Very low37.9Very low105 Ų105133.7 Ų133.768%0.68270%0.703SS**G310 helixtrans-57.6-14.8-177.2-24.833.5000115.1S615P613-S615 VanDerWaalsContact C-N 3.31Å; P613-S615 PolarHBondContact O-N 3.41Å
614Q31.6Very low36.2Very low165 Ų165135.6 Ų135.677%0.77171%0.713SS**G310 helixtrans-80.8-6.4-178.9-73.4172.2-22.600114.1S612S612-Q614 PolarHBondContact O-N 2.03Å
615S29.4Very low34.4Very low69 Ų69140.2 Ų140.248%0.48374%0.741SS.*G310 helixtrans-91.1-3.6-177.448.40000115S612 P613S612-S615 PolarHBondContact O-N 3.33Å; S612-S615 VanDerWaalsContact O-N 3.13Å; S612-S615 PolarHBondContact O-OG 3.11Å; P613-S615 VanDerWaalsContact C-N 3.31Å; P613-S615 PolarHBondContact O-N 3.41Å
616L37Very low32.9Very low122 Ų122140.3 Ų140.364%0.63974%0.744SS**G310 helixtrans-89-1.1170.5-84156.9000113.3L60L60-L616 HydrophobicContact CD1-CD2 4.39Å
617I34.2Very low31.7Very low129 Ų129146.8 Ų146.866%0.66277%0.771SS**SBendtrans-129.399.3179.7-53.7175.5000107.7
618L30.4Very low30.8Very low151 Ų151146.5 Ų146.579%0.79177%0.772SS**  trans134.574.7162.8-75.1156.6000112.7
619Q29.4Very low30.1Very low210 Ų210146.3 Ų146.398%0.98177%0.771SS**  trans-135.375.2141.8-81.6-167.9-7.900108.6
620G36.1Very low29.8Very low64 Ų64144 Ų14466%0.6678%0.777SS**  trans-158.864.1177.800000109.9
621Q26.1Very low29.4Very low186 Ų186135.7 Ų135.787%0.86977%0.77SS**  trans-163.5122.7154.4-116.7168-700111.5
622E29Very low29Very low189 Ų189140.1 Ų140.188%0.88378%0.784SS**  trans-48.9143.6168.8-68.5168.9126.800112.1
623L24.9Very low28.7Very low172 Ų172142 Ų14290%0.90180%0.804SS**  trans-120106.8158.4-96.9158.9000109.4
624Q26.1Very low28.1Very low179 Ų179144.6 Ų144.684%0.83681%0.809SS**  trans-54.7141.5162.2-71.3-170.8-30.200110.8
625V23.6Very low27.7Very low140 Ų140144 Ų14485%0.84881%0.811SS**  trans-73.7128.6171.6175.30000109.6
626S23.4Very low27.6Very low114 Ų114147.7 Ų147.780%0.79782%0.82SS**  trans-136.3132.7154.4680000110
627E26.2Very low27.1Very low182 Ų182150 Ų15085%0.8583%0.828SS**  trans-66.8172.9-177.9-69.5177.2127.100115.3
628E25.7Very low26.6Very low201 Ų201149.7 Ų149.794%0.93983%0.832SS**  trans98.4125.5169.4-63.3-172.816000115.3
629G26.7Very low26.4Very low73 Ų73149.9 Ų149.975%0.75383%0.833SS**  cis170.8150.3-300000110.6
630S27Very low26.6Very low136 Ų136146 Ų14695%0.95183%0.825SS**  trans72.6121154.3-172.40000122
631G26.3Very low26Very low77 Ų77148.9 Ų148.979%0.79483%0.83SS**  trans170.185.3155.700000115.9
632K28Very low25.9Very low212 Ų212145.9 Ų145.992%0.92283%0.83SS**  trans-54.4148.7179-72169.5168.3175.60116.3
633A24.6Very low25.7Very low106 Ų106144.3 Ų144.388%0.87683%0.827SS**  -171.1136.1119.700000112.8
634M24.4Very low25.7Very low160 Ų160141.6 Ų141.679%0.78882%0.822SS**  trans-88.7157.3177-82-178.666.900113.2
635L23.9Very low25.6Very low153 Ų153142.7 Ų142.780%0.80183%0.827SS**  168.9104.3129.9-94.5144.1000109.2
636E26.5Very low25.6Very low146 Ų146140 Ų14068%0.68283%0.828SS**  61.8107.2101.9-103.6175.3173.800115.9
637E26.3Very low25.6Very low170 Ų170143.5 Ų143.579%0.79483%0.832SS**  83.5128.7107.1-110.2-167.4-169.200113.2
638V24.3Very low26Very low123 Ų123140 Ų14075%0.74583%0.825SS**  178.814476.8165.20000109.4
639L26.3Very low25.9Very low155 Ų155135.3 Ų135.381%0.81281%0.814SS**  trans-90.2161.6162.2-79.2164.7000111.5
640P32.3Very low25.8Very low128 Ų128142.2 Ų142.283%0.83182%0.817SS**  -143.1158.6124.729.5-10.9000116.7
641V25.1Very low25.8Very low124 Ų124142.9 Ų142.975%0.75281%0.805SS**  trans-99.7148.3175.5169.40000110.1
642S24.3Very low25.7Very low124 Ų124146.6 Ų146.687%0.86780%0.8SS**  trans-161.2140.6145.762.60000114.2
643L24.3Very low25.5Very low156 Ų156147.4 Ų147.482%0.81780%0.797SS**  trans-95.9155.9-177.3-88.2119.5000114.5
644S24Very low25.5Very low115 Ų115146.7 Ų146.780%0.80479%0.786SS**  trans172.5110.4134.943.40000110.4
645Q25.2Very low25.7Very low202 Ų202145 Ų14594%0.94478%0.784SS**  72.7119.985-89.8-167.4-8.100118.2
646G23.3Very low25.9Very low84 Ų84146 Ų14687%0.86679%0.785SS**  trans162.397.9161.300000115.8
647Q23.6Very low26.1Very low187 Ų187145.8 Ų145.887%0.87479%0.788SS**  trans-94.8173.6177.2-120.7178.6-17.400111.3
648P34.2Very low26.1Very low109 Ų109143.5 Ų143.571%0.70879%0.786SS**  -154.6155.752.639.2-15.9000121.2
649S24.2Very low26.2Very low102 Ų102140.9 Ų140.971%0.71378%0.784SS**  trans65.3136.6144.873.50000119.9
650R24.1Very low27Very low218 Ų218139.5 Ų139.582%0.82378%0.784SS**  -169.8125.356.3-152.5176.9-172.7176.32.4112.4
651Q25.5Very low26.7Very low149 Ų149140.7 Ų140.770%0.69678%0.783SS**  trans44.7140.2143.5-71.2-175.7-22.800121.3
652K26.2Very low26.9Very low156 Ų156143 Ų14368%0.67879%0.785SS**  cis-172.4141.821.6-124.6166.2-175.8175.50110.7
653R23.1Very low27.3Very low228 Ų228144.3 Ų144.386%0.8678%0.783SS**  trans45.4141.9138.1-85.3-171.7173.7172-3.8119.7
654S25.1Very low28.2Very low92 Ų92145.7 Ų145.764%0.64378%0.784SS**  cis164.2146.8651.70000103.9
655V27.7Very low28.6Very low125 Ų125147.5 Ų147.576%0.75879%0.785SS**  177.9133.163.5158.70000105.2
656E28.8Very low28.9Very low173 Ų173148.1 Ų148.181%0.80878%0.779SS**  trans-68.4143.2157.4-73166.8130.100110.1
657N29.6Very low29.4Very low142 Ų142148.6 Ų148.676%0.75977%0.767SS**  -174139.3129-102.3-17.4000115.6
658T27.5Very low30.3Very low121 Ų121148.6 Ų148.674%0.74277%0.767SS**  trans68.5111.6137.257.70000120.2
659G26.5Very low30.8Very low68 Ų68154 Ų15470%0.70177%0.774SS**  trans-77.4-167.2141.600000111.7
660P41.6Very low31.9Very low127 Ų127157.9 Ų157.983%0.82578%0.779SS**  -115.4147.1-85.835.3-28000111.8
661L25.6Very low33.7Very low152 Ų152158 Ų15880%0.79678%0.78SS**  trans-149.5119.5165.9-113.9113.9000111.5
662E31.1Very low36.2Very low172 Ų172155.1 Ų155.180%0.80477%0.769SS**  trans51106.3140.3-62.9-177.516200119.4H664E662-H664 PolarHBondContact O-N 3.12Å
663D32.9Very low38.8Very low153 Ų153149.9 Ų149.982%0.81875%0.751SS**  trans-92.986.9173.3-141.41000110.5
664H41.4Very low41.8Very low184 Ų184140.1 Ų140.185%0.85272%0.717SS**  trans-128.2113.6158.2-83.2-26.5000109E662E662-H664 PolarHBondContact O-N 3.12Å
665N33.5Very low44.6Very low153 Ų153141.8 Ų141.882%0.81872%0.719SS**  147.978.6120.8-152.817.4000111.1
666W30.6Very low47.1Very low216 Ų216141 Ų14182%0.81872%0.717SS**  trans-87135.2165.7-137.4-100.4000109.8Q668W666-Q668 PolarHBondContact O-N 3.27Å
667P34.1Very low50Low94 Ų94136.9 Ų136.961%0.6170%0.7SS**  trans-58.5135.5-177.5-22.731.7000113.1Y669P667-Y669 PolarHBondContact O-N 3.47Å
668Q42.6Very low52.8Low186 Ų186131.9 Ų131.987%0.86968%0.675SS**THydrogen-bonded Turntrans-59.58-175.7-114.8171.8-500116.9W666W666-Q668 PolarHBondContact O-N 3.27Å
669Y44.4Very low55.8Low222 Ų222127 Ų12787%0.87165%0.645SS**THydrogen-bonded Turntrans-995.9-174.5-94.7-90.4000114.9P667P667-Y669 PolarHBondContact O-N 3.47Å
670F47.3Very low58.8Low185 Ų185128.2 Ų128.281%0.81163%0.633SS**SBendtrans-125.315.7-178.6-90.1-77.7000115.4
671R62.3Low61Low221 Ų221125.4 Ų125.483%0.83461%0.611SS**SBendtrans-85.8130.8167.9-74.6-170.9-177.9-173.8-0.5109.6P673R671-P673 WeakPolarHBondContact O-CD 3.02Å
672D78.2Confident63.8Low87 Ų87124.7 Ų124.747%0.46561%0.608SS.*  trans-63.2120.6171.9-171.9-12.9000108.3C674 D675D672-C674 PolarHBondContact O-N 3.12Å; D672-C674 WeakPolarHBondContact OD1-CB 3.42Å; D672-C674 PolarHBondContact OD1-N 3.22Å; D672-D675 HydrophobicContact CB-CB 4.41Å; D672-D675 PolarHBondContact O-N 3.19Å
673P80.5Confident66.5Low47 Ų47116.6 Ų116.631%0.30557%0.57SS.*THydrogen-bonded Turntrans-61-12.7176.826.8-37.2000113.5R671 N687 A692R671-P673 WeakPolarHBondContact O-CD 3.02Å; P673-N687 VanDerWaalsContact CD-ND2 3.33Å; P673-N687 WeakPolarHBondContact CD-ND2 3.41Å; P673-N687 HydrophobicContact CG-CB 4.25Å; P673-N687 WeakPolarHBondContact CG-ND2 3.26Å; P673-A692 HydrophobicContact CB-CB 4.07Å; P673-A692 WeakPolarHBondContact O-CB 3.48Å
674C87Confident69.3Low22 Ų22113.4 Ų113.415%0.14956%0.557CS.*THydrogen-bonded Turntrans-88.93.7172.6-69.20000114.7D672 P676 N677 C685D672-C674 PolarHBondContact O-N 3.12Å; D672-C674 WeakPolarHBondContact OD1-CB 3.42Å; D672-C674 PolarHBondContact OD1-N 3.22Å; C674-P676 CarbonylContact O-C 3.41Å; C674-P676 VanDerWaalsContact O-C 3.25Å; C674-N677 WeakPolarHBondContact O-CA 3.41Å; C674-N677 PolarHBondContact O-N 3.39Å; C674-C685 WeakPolarHBondContact CA-SG 3.36Å; C674-C685 HydrophobicContact CB-CB 3.65Å; C674-C685 WeakPolarHBondContact CB-SG 3.45Å; C674-C685 WeakPolarHBondContact SG-CB 3.19Å; C674-C685 CovalentContact SG-SG 2.04Å; C674-C685 PolarHBondContact SG-SG 2.94Å
675D82.8Confident71.7Confident128 Ų128105.7 Ų105.768%0.68452%0.523SS*.SBendtrans-124.1109.7177.2-171.514.4000112.2D672D672-D675 HydrophobicContact CB-CB 4.41Å; D672-D675 PolarHBondContact O-N 3.19Å
676P80.3Confident74.4Confident109 Ų109100.6 Ų100.671%0.70850%0.497SS*.SBendcis-73.9153.4-0.730.3-34.8000112.8C674 P678C674-P676 CarbonylContact O-C 3.41Å; C674-P676 VanDerWaalsContact O-C 3.25Å; P676-P678 VanDerWaalsContact O-CD 3.24Å; P676-P678 WeakPolarHBondContact O-CD 3.44Å; P676-P678 VanDerWaalsContact O-N 3.14Å
677N89.4Confident77.1Confident86 Ų8694 Ų9446%0.4648%0.478SS..  trans-58.3115.1-177-179.1-0.7000111.1C674 C679 G683 C685C674-N677 WeakPolarHBondContact O-CA 3.41Å; C674-N677 PolarHBondContact O-N 3.39Å; N677-C679 VanDerWaalsContact C-N 3.3Å; N677-C679 PolarHBondContact O-N 3.36Å; N677-C679 VanDerWaalsContact OD1-CB 3.24Å; N677-C679 WeakPolarHBondContact OD1-CB 3.45Å; N677-C679 PolarHBondContact OD1-N 3.15Å; N677-C679 PolarHBondContact OD1-SG 2.92Å; N677-C679 VanDerWaalsContact OD1-SG 3.32Å; N677-G683 PolarHBondContact ND2-O 3.4Å; N677-G683 VanDerWaalsContact ND2-O 3.15Å; N677-C685 VanDerWaalsContact OD1-CB 3.27Å; N677-C685 WeakPolarHBondContact OD1-CB 3.17Å
678P88.9Confident79.5Confident37 Ų3792.9 Ų92.924%0.2447%0.469CS..  trans-82.8-2.4-17733.4-35.2000114.3P676 A692P676-P678 VanDerWaalsContact O-CD 3.24Å; P676-P678 WeakPolarHBondContact O-CD 3.44Å; P676-P678 VanDerWaalsContact O-N 3.14Å; P678-A692 HydrophobicContact CG-CB 3.63Å
679C91.7Very high81.2Confident17 Ų1794 Ų9412%0.11547%0.471CS..  trans-82.3143.8-177.7-54.20000112.2N677 G683 C685 C694N677-C679 VanDerWaalsContact C-N 3.3Å; N677-C679 PolarHBondContact O-N 3.36Å; N677-C679 VanDerWaalsContact OD1-CB 3.24Å; N677-C679 WeakPolarHBondContact OD1-CB 3.45Å; N677-C679 PolarHBondContact OD1-N 3.15Å; N677-C679 PolarHBondContact OD1-SG 2.92Å; N677-C679 VanDerWaalsContact OD1-SG 3.32Å; C679-G683 WeakPolarHBondContact CB-O 3.46Å; C679-C685 VanDerWaalsContact SG-CA 3.57Å; C679-C694 WeakPolarHBondContact CA-SG 3.31Å; C679-C694 HydrophobicContact CB-CB 3.78Å; C679-C694 WeakPolarHBondContact CB-SG 3.31Å; C679-C694 WeakPolarHBondContact SG-CA 3.22Å; C679-C694 WeakPolarHBondContact SG-CB 3.44Å; C679-C694 CovalentContact SG-SG 2.02Å; C679-C694 PolarHBondContact SG-SG 2.74Å
680Q87.9Confident82.9Confident95 Ų9586 Ų8644%0.44446%0.456SS..SBendtrans-100.5165.5177.9-59-178-0.300110.7D682 G683 R708 C709 Q710Q680-D682 VanDerWaalsContact C-N 3.29Å; Q680-D682 PolarHBondContact O-N 2.87Å; Q680-G683 PolarHBondContact O-N 3.05Å; Q680-R708 WeakPolarHBondContact CB-O 3.37Å; Q680-R708 PolarHBondContact N-O 3.12Å; Q680-C709 WeakPolarHBondContact O-CB 3.37Å; Q680-Q710 VanDerWaalsContact OE1-CB 3.32Å
681N88.5Confident84.3Confident67 Ų6784.1 Ų84.136%0.35845%0.452SS..THydrogen-bonded Turntrans51.247.5175.6-54.9-44.2000112.8G683 Y704 C709N681-G683 PolarHBondContact O-N 3Å; N681-G683 VanDerWaalsContact O-N 3.11Å; N681-Y704 HydrophobicContact CB-CD1 3.89Å; N681-Y704 HydrophobicContact CB-CD2 4.19Å; N681-Y704 HydrophobicContact CB-CE1 3.79Å; N681-Y704 HydrophobicContact CB-CE2 4.08Å; N681-Y704 HydrophobicContact CB-CG 4.09Å; N681-C709 PolarHBondContact ND2-O 3.09Å
682D85.1Confident85.6Confident138 Ų13875.5 Ų75.574%0.73843%0.428SS*.THydrogen-bonded Turntrans57.923.5-179-52.7-46.8000114.6Q680 V684 I697Q680-D682 VanDerWaalsContact C-N 3.29Å; Q680-D682 PolarHBondContact O-N 2.87Å; D682-V684 PolarHBondContact O-N 3.46Å; D682-I697 HydrophobicContact CB-CD1 3.57Å; D682-I697 WeakPolarHBondContact O-CD1 3.25Å
683G87.4Confident86.3Confident1 Ų173.6 Ų73.61%0.0142%0.421CS..PPolyproline II helixtrans-59.2136.5172.100000111.8N677 C679 Q680 N681 R695N677-G683 PolarHBondContact ND2-O 3.4Å; N677-G683 VanDerWaalsContact ND2-O 3.15Å; C679-G683 WeakPolarHBondContact CB-O 3.46Å; Q680-G683 PolarHBondContact O-N 3.05Å; N681-G683 PolarHBondContact O-N 3Å; N681-G683 VanDerWaalsContact O-N 3.11Å; G683-R695 WeakPolarHBondContact CA-O 3.27Å
684V90.8Very high86.9Confident87 Ų8772.2 Ų72.253%0.52741%0.412SS..EExtended strand (participates in β ladder)trans-85.6119.3178.3-179.70000109D682 R695D682-V684 PolarHBondContact O-N 3.46Å; V684-R695 HydrophobicContact CB-CB 4.34Å; V684-R695 PolarHBondContact N-O 3.22Å; V684-R695 PolarHBondContact O-N 2.67Å
685C91.8Very high87.1Confident21 Ų2178.7 Ų78.714%0.14243%0.434CS..EExtended strand (participates in β ladder)trans-75.8131.2172.9-1730000110.8C674 N677 C679 A692C674-C685 WeakPolarHBondContact CA-SG 3.36Å; C674-C685 HydrophobicContact CB-CB 3.65Å; C674-C685 WeakPolarHBondContact CB-SG 3.45Å; C674-C685 WeakPolarHBondContact SG-CB 3.19Å; C674-C685 CovalentContact SG-SG 2.04Å; C674-C685 PolarHBondContact SG-SG 2.94Å; N677-C685 VanDerWaalsContact OD1-CB 3.27Å; N677-C685 WeakPolarHBondContact OD1-CB 3.17Å; C679-C685 VanDerWaalsContact SG-CA 3.57Å; C685-A692 VanDerWaalsContact SG-CB 3.52Å
686V91.3Very high87.5Confident47 Ų4774.6 Ų74.629%0.28542%0.415SS..EExtended strand (participates in β ladder)trans-123.9129.9170.2-670000109.3V688 S693 R695V686-V688 HydrophobicContact CG2-CG2 4Å; V686-V688 PolarHBondContact O-N 2.98Å; V686-S693 VanDerWaalsContact CG2-O 3.26Å; V686-S693 WeakPolarHBondContact CG2-O 3.42Å; V686-S693 PolarHBondContact N-O 2.61Å; V686-S693 PolarHBondContact O-N 2.92Å; V686-R695 HydrophobicContact CG1-CG 4.29Å; V686-R695 HydrophobicContact CG2-CG 3.93Å
687N87.5Confident87.6Confident78 Ų7873.1 Ų73.142%0.41740%0.4SS..EExtended strand (participates in β ladder)trans-76.9110175.2-176.7-14.9000109.6P673 G690P673-N687 VanDerWaalsContact CD-ND2 3.33Å; P673-N687 WeakPolarHBondContact CD-ND2 3.41Å; P673-N687 HydrophobicContact CG-CB 4.25Å; P673-N687 WeakPolarHBondContact CG-ND2 3.26Å; N687-G690 WeakPolarHBondContact OD1-CA 3.41Å; N687-G690 PolarHBondContact OD1-N 2.98Å
688V83.7Confident87.3Confident69 Ų6973 Ų7342%0.41841%0.406SS..EExtended strand (participates in β ladder)trans-113106178.4-176.70000108.1V686 G690 M691V686-V688 HydrophobicContact CG2-CG2 4Å; V686-V688 PolarHBondContact O-N 2.98Å; V688-G690 VanDerWaalsContact C-N 3.3Å; V688-G690 PolarHBondContact O-N 3.35Å; V688-M691 PolarHBondContact N-O 3.08Å; V688-M691 PolarHBondContact O-N 3.24Å
689K78.7Confident86.8Confident210 Ų21072.1 Ų72.191%0.91340%0.404SS*.THydrogen-bonded Turntrans56.538.6178.6-58.5178.5176.8178.10113.8
690G79.4Confident85.6Confident54 Ų5477.6 Ų77.656%0.55744%0.439SS*.THydrogen-bonded Turntrans84.19.9177.900000114.4N687 V688N687-G690 WeakPolarHBondContact OD1-CA 3.41Å; N687-G690 PolarHBondContact OD1-N 2.98Å; V688-G690 VanDerWaalsContact C-N 3.3Å; V688-G690 PolarHBondContact O-N 3.35Å
691M77.7Confident84.8Confident145 Ų14575 Ų7571%0.71444%0.435SS*.EExtended strand (participates in β ladder)trans-123.6140.7175.3-59.7-177.881.300110.1V688 S693V688-M691 PolarHBondContact N-O 3.08Å; V688-M691 PolarHBondContact O-N 3.24Å; M691-S693 PolarHBondContact O-N 3.4Å
692A88.7Confident84.5Confident41 Ų4175.4 Ų75.434%0.33943%0.433SS..EExtended strand (participates in β ladder)trans-69.1127.4172.600000110.6P673 P678 C685P673-A692 HydrophobicContact CB-CB 4.07Å; P673-A692 WeakPolarHBondContact O-CB 3.48Å; P678-A692 HydrophobicContact CG-CB 3.63Å; C685-A692 VanDerWaalsContact SG-CB 3.52Å
693S92.9Very high84.6Confident46 Ų4671.8 Ų71.832%0.32241%0.411SS..EExtended strand (participates in β ladder)trans-125131.8172.7179.60000109.1V686 M691V686-S693 VanDerWaalsContact CG2-O 3.26Å; V686-S693 WeakPolarHBondContact CG2-O 3.42Å; V686-S693 PolarHBondContact N-O 2.61Å; V686-S693 PolarHBondContact O-N 2.92Å; M691-S693 PolarHBondContact O-N 3.4Å
694C93.6Very high84.7Confident18 Ų1874.3 Ų74.312%0.12242%0.42CS..EExtended strand (participates in β ladder)trans-91.7135.6-178.5-63.10000112.5C679 E707C679-C694 WeakPolarHBondContact CA-SG 3.31Å; C679-C694 HydrophobicContact CB-CB 3.78Å; C679-C694 WeakPolarHBondContact CB-SG 3.31Å; C679-C694 WeakPolarHBondContact SG-CA 3.22Å; C679-C694 WeakPolarHBondContact SG-CB 3.44Å; C679-C694 CovalentContact SG-SG 2.02Å; C679-C694 PolarHBondContact SG-SG 2.74Å; C694-E707 WeakPolarHBondContact CB-O 3.33Å
695R91.6Very high84.5Confident159 Ų15972.3 Ų72.360%0.641%0.408SS*.EExtended strand (participates in β ladder)trans-103.7113.1169.5-61.9-62.5-175.8174.4-0.6108.5G683 V684 V686G683-R695 WeakPolarHBondContact CA-O 3.27Å; V684-R695 HydrophobicContact CB-CB 4.34Å; V684-R695 PolarHBondContact N-O 3.22Å; V684-R695 PolarHBondContact O-N 2.67Å; V686-R695 HydrophobicContact CG1-CG 4.29Å; V686-R695 HydrophobicContact CG2-CG 3.93Å
696C90.8Very high84.2Confident42 Ų4273.2 Ų73.228%0.28442%0.421SS..  trans-85.1140.4-173.7-50.70000111.7Y704 C709C696-Y704 WeakPolarHBondContact CB-O 3.36Å; C696-C709 WeakPolarHBondContact CA-SG 3.43Å; C696-C709 HydrophobicContact CB-CB 3.69Å; C696-C709 WeakPolarHBondContact CB-SG 3.29Å; C696-C709 PolarHBondContact N-SG 3.26Å; C696-C709 VanDerWaalsContact N-SG 3.39Å; C696-C709 WeakPolarHBondContact SG-CA 2.99Å; C696-C709 WeakPolarHBondContact SG-CB 3.32Å; C696-C709 CovalentContact SG-SG 2.03Å; C696-C709 PolarHBondContact SG-SG 3.49Å
697I83Confident84Confident77 Ų7779.5 Ų79.540%0.39545%0.448SS..  trans-69.8138.5176.6-61.3175.1000109.4D682 Y704D682-I697 HydrophobicContact CB-CD1 3.57Å; D682-I697 WeakPolarHBondContact O-CD1 3.25Å; I697-Y704 PolarHBondContact O-N 3.28Å; I697-Y704 VanDerWaalsContact O-N 3.09Å
698S83Confident84.1Confident83 Ų8382.4 Ų82.458%0.5845%0.453SS*.BIsolated β-bridgetrans-123.9119.3173.7-173.10000108.8F703S698-F703 WeakPolarHBondContact OG-CB 3.3Å
699G77.8Confident84.4Confident20 Ų2079.1 Ų79.121%0.20643%0.433CS..  trans-102.2178.5172.500000112.2A701 F702G699-A701 VanDerWaalsContact C-N 3.27Å; G699-A701 PolarHBondContact O-N 2.91Å; G699-F702 CarbonylContact C-O 3.55Å; G699-F702 WeakPolarHBondContact CA-O 3.38Å; G699-F702 PolarHBondContact N-O 3.27Å
700P67.3Low85Confident131 Ų13173.9 Ų73.985%0.85141%0.412SS*.SBendtrans-65.9-27.3-177.2-19.931.4000114
701A70.4Confident85.3Confident42 Ų4273 Ų7335%0.34740%0.399SS..SBendtrans-108.9-28-175.400000113.6G699 V714 H715 V718G699-A701 VanDerWaalsContact C-N 3.27Å; G699-A701 PolarHBondContact O-N 2.91Å; A701-V714 WeakPolarHBondContact O-CA 3.37Å; A701-V714 WeakPolarHBondContact O-CG1 3.44Å; A701-H715 PolarHBondContact O-N 3.11Å; A701-V718 HydrophobicContact CB-CG2 4.45Å
702F82.6Confident85.7Confident74 Ų7470.9 Ų70.933%0.32539%0.389SS..EExtended strand (participates in β ladder)trans-145.4157.2-176.763.6-92.4000111.5G699 Y704 M712 Q713G699-F702 CarbonylContact C-O 3.55Å; G699-F702 WeakPolarHBondContact CA-O 3.38Å; G699-F702 PolarHBondContact N-O 3.27Å; F702-Y704 HydrophobicContact CD2-CE2 4.07Å; F702-Y704 AromaticContact CE2-CE2 3.7Å; F702-Y704 HydrophobicContact CE2-CE2 3.7Å; F702-M712 HydrophobicContact CB-CE 3.51Å; F702-M712 HydrophobicContact CB-CG 4.31Å; F702-M712 HydrophobicContact CD1-CE 3.78Å; F702-M712 HydrophobicContact CD2-CE 3.67Å; F702-M712 HydrophobicContact CD2-CG 4.35Å; F702-M712 HydrophobicContact CE1-CE 4.41Å; F702-M712 HydrophobicContact CE2-CE 4.33Å; F702-M712 HydrophobicContact CG-CE 3.36Å; F702-Q713 CarbonylContact C-O 3.43Å; F702-Q713 WeakPolarHBondContact CA-O 3.25Å; F702-Q713 WeakPolarHBondContact CB-O 3.36Å
703F86.8Confident85.4Confident62 Ų6273.4 Ų73.427%0.27239%0.393SS..EExtended strand (participates in β ladder)trans-141.6146.9176.560-83.5000110S698 T705 Q713S698-F703 WeakPolarHBondContact OG-CB 3.3Å; F703-T705 HydrophobicContact CD2-CG2 3.47Å; F703-T705 VanDerWaalsContact CD2-CG2 3.47Å; F703-T705 HydrophobicContact CE2-CG2 3.41Å; F703-T705 VanDerWaalsContact CE2-CG2 3.41Å; F703-Q713 HydrophobicContact CD1-CB 4.11Å; F703-Q713 HydrophobicContact CD2-CB 3.95Å; F703-Q713 HydrophobicContact CE1-CB 3.69Å; F703-Q713 HydrophobicContact CE2-CB 3.53Å; F703-Q713 HydrophobicContact CE2-CG 3.93Å; F703-Q713 HydrophobicContact CG-CB 4.22Å; F703-Q713 HydrophobicContact CZ-CB 3.38Å; F703-Q713 HydrophobicContact CZ-CG 4.1Å; F703-Q713 PolarHBondContact N-O 3.23Å; F703-Q713 PolarHBondContact O-N 2.81Å
704Y90.1Very high84.8Confident54 Ų5475 Ų7521%0.21240%0.401CS..EExtended strand (participates in β ladder)trans-92.6146.1175.7-65-78.8000111.1N681 C696 I697 F702 A711 M712N681-Y704 HydrophobicContact CB-CD1 3.89Å; N681-Y704 HydrophobicContact CB-CD2 4.19Å; N681-Y704 HydrophobicContact CB-CE1 3.79Å; N681-Y704 HydrophobicContact CB-CE2 4.08Å; N681-Y704 HydrophobicContact CB-CG 4.09Å; C696-Y704 WeakPolarHBondContact CB-O 3.36Å; I697-Y704 PolarHBondContact O-N 3.28Å; I697-Y704 VanDerWaalsContact O-N 3.09Å; F702-Y704 HydrophobicContact CD2-CE2 4.07Å; F702-Y704 AromaticContact CE2-CE2 3.7Å; F702-Y704 HydrophobicContact CE2-CE2 3.7Å; Y704-A711 CarbonylContact C-O 3.49Å; Y704-A711 WeakPolarHBondContact CA-O 3.39Å; Y704-M712 HydrophobicContact CD1-CB 3.86Å; Y704-M712 HydrophobicContact CD1-CG 4.25Å; Y704-M712 HydrophobicContact CE1-CB 3.66Å; Y704-M712 HydrophobicContact CE1-CG 3.83Å; Y704-M712 HydrophobicContact CE1-SD 4.47Å
705T85.9Confident83.9Confident45 Ų4577.6 Ų77.628%0.27641%0.411SS..EExtended strand (participates in β ladder)trans-138.8164.3-176.660.30000111F703 C709 Q710 A711 Q713F703-T705 HydrophobicContact CD2-CG2 3.47Å; F703-T705 VanDerWaalsContact CD2-CG2 3.47Å; F703-T705 HydrophobicContact CE2-CG2 3.41Å; F703-T705 VanDerWaalsContact CE2-CG2 3.41Å; T705-C709 CarbonylContact O-C 3.44Å; T705-Q710 PolarHBondContact O-N 3.06Å; T705-A711 PolarHBondContact N-O 2.63Å; T705-A711 WeakPolarHBondContact O-CB 3.47Å; T705-A711 PolarHBondContact O-N 2.9Å; T705-A711 PolarHBondContact OG1-O 3.23Å; T705-Q713 HydrophobicContact CG2-CG 3.96Å
706G85.3Confident82.6Confident40 Ų4072.8 Ų72.841%0.41241%0.411SS..SBendtrans102.1161.2-176.700000112.7R708 C709G706-R708 PolarHBondContact O-N 3.03Å; G706-R708 VanDerWaalsContact O-N 3.09Å; G706-C709 PolarHBondContact O-N 2.85Å
707E86.9Confident81.4Confident180 Ų18074.5 Ų74.584%0.84142%0.424SS*.THydrogen-bonded Turntrans-59.4-23.8-173.9-64.7-172.3161.600114.2C694C694-E707 WeakPolarHBondContact CB-O 3.33Å
708R89.8Confident80.4Confident139 Ų13972.9 Ų72.953%0.52542%0.417SS..THydrogen-bonded Turntrans-120.617.1175.7-62.7-174.1178.8-171.2-1.3113Q680 G706 Q710Q680-R708 WeakPolarHBondContact CB-O 3.37Å; Q680-R708 PolarHBondContact N-O 3.12Å; G706-R708 PolarHBondContact O-N 3.03Å; G706-R708 VanDerWaalsContact O-N 3.09Å; R708-Q710 VanDerWaalsContact C-N 3.25Å; R708-Q710 PolarHBondContact O-N 3.19Å
709C91.1Very high79.1Confident0 Ų074 Ų740%042%0.417CS..SBendtrans62.428.1-176.6-49.90000114.8Q680 N681 C696 T705 G706 A711Q680-C709 WeakPolarHBondContact O-CB 3.37Å; N681-C709 PolarHBondContact ND2-O 3.09Å; C696-C709 WeakPolarHBondContact CA-SG 3.43Å; C696-C709 HydrophobicContact CB-CB 3.69Å; C696-C709 WeakPolarHBondContact CB-SG 3.29Å; C696-C709 PolarHBondContact N-SG 3.26Å; C696-C709 VanDerWaalsContact N-SG 3.39Å; C696-C709 WeakPolarHBondContact SG-CA 2.99Å; C696-C709 WeakPolarHBondContact SG-CB 3.32Å; C696-C709 CovalentContact SG-SG 2.03Å; C696-C709 PolarHBondContact SG-SG 3.49Å; T705-C709 CarbonylContact O-C 3.44Å; G706-C709 PolarHBondContact O-N 2.85Å; C709-A711 VanDerWaalsContact C-N 3.35Å; C709-A711 PolarHBondContact O-N 3.19Å
710Q90Very high78.2Confident100 Ų10075.1 Ų75.147%0.46743%0.428SS..  trans-74.3-18.1-173.367.9-86.92100114.9Q680 T705 R708Q680-Q710 VanDerWaalsContact OE1-CB 3.32Å; T705-Q710 PolarHBondContact O-N 3.06Å; R708-Q710 VanDerWaalsContact C-N 3.25Å; R708-Q710 PolarHBondContact O-N 3.19Å
711A86.9Confident77.9Confident36 Ų3675.3 Ų75.330%0.29842%0.419SS..EExtended strand (participates in β ladder)trans-115.5114.1-170.800000112.3Y704 T705 C709Y704-A711 CarbonylContact C-O 3.49Å; Y704-A711 WeakPolarHBondContact CA-O 3.39Å; T705-A711 PolarHBondContact N-O 2.63Å; T705-A711 WeakPolarHBondContact O-CB 3.47Å; T705-A711 PolarHBondContact O-N 2.9Å; T705-A711 PolarHBondContact OG1-O 3.23Å; C709-A711 VanDerWaalsContact C-N 3.35Å; C709-A711 PolarHBondContact O-N 3.19Å
712M85.5Confident77.6Confident100 Ų10077.6 Ų77.649%0.49343%0.428SS..EExtended strand (participates in β ladder)trans-75.9137.5173.3-168.6-175178.800111.2F702 Y704F702-M712 HydrophobicContact CB-CE 3.51Å; F702-M712 HydrophobicContact CB-CG 4.31Å; F702-M712 HydrophobicContact CD1-CE 3.78Å; F702-M712 HydrophobicContact CD2-CE 3.67Å; F702-M712 HydrophobicContact CD2-CG 4.35Å; F702-M712 HydrophobicContact CE1-CE 4.41Å; F702-M712 HydrophobicContact CE2-CE 4.33Å; F702-M712 HydrophobicContact CG-CE 3.36Å; Y704-M712 HydrophobicContact CD1-CB 3.86Å; Y704-M712 HydrophobicContact CD1-CG 4.25Å; Y704-M712 HydrophobicContact CE1-CB 3.66Å; Y704-M712 HydrophobicContact CE1-CG 3.83Å; Y704-M712 HydrophobicContact CE1-SD 4.47Å
713Q82.6Confident76.7Confident93 Ų9379.1 Ų79.144%0.43544%0.439SS..EExtended strand (participates in β ladder)trans-129.4148175.4-64.7-63.9-38.200109.4F702 F703 T705F702-Q713 CarbonylContact C-O 3.43Å; F702-Q713 WeakPolarHBondContact CA-O 3.25Å; F702-Q713 WeakPolarHBondContact CB-O 3.36Å; F703-Q713 HydrophobicContact CD1-CB 4.11Å; F703-Q713 HydrophobicContact CD2-CB 3.95Å; F703-Q713 HydrophobicContact CE1-CB 3.69Å; F703-Q713 HydrophobicContact CE2-CB 3.53Å; F703-Q713 HydrophobicContact CE2-CG 3.93Å; F703-Q713 HydrophobicContact CG-CB 4.22Å; F703-Q713 HydrophobicContact CZ-CB 3.38Å; F703-Q713 HydrophobicContact CZ-CG 4.1Å; F703-Q713 PolarHBondContact N-O 3.23Å; F703-Q713 PolarHBondContact O-N 2.81Å; T705-Q713 HydrophobicContact CG2-CG 3.96Å
714V79.4Confident75.5Confident80 Ų8078.2 Ų78.249%0.48545%0.447SS..EExtended strand (participates in β ladder)trans-109138.9179.6178.40000109.1A701 G716 V718A701-V714 WeakPolarHBondContact O-CA 3.37Å; A701-V714 WeakPolarHBondContact O-CG1 3.44Å; V714-G716 PolarHBondContact O-N 3.08Å; V714-V718 HydrophobicContact CG1-CB 4.22Å; V714-V718 HydrophobicContact CG1-CG1 4.43Å
715H74.9Confident74.4Confident72 Ų7277.6 Ų77.633%0.33346%0.457SS..  trans-60.5130.1177-92.2-73.7000111.1A701 S717 V718 L719A701-H715 PolarHBondContact O-N 3.11Å; H715-S717 PolarHBondContact O-N 3.24Å; H715-S717 VanDerWaalsContact O-N 3.09Å; H715-V718 HydrophobicContact CB-CG2 4.29Å; H715-V718 WeakPolarHBondContact O-CB 3.18Å; H715-V718 PolarHBondContact O-N 3.32Å; H715-L719 PolarHBondContact O-N 3.39Å
716G64.9Low73.4Confident58 Ų5879.2 Ų79.260%0.59847%0.467SS*.Hα-helixtrans-59-24-177.700000114.8V714 L719 G720V714-G716 PolarHBondContact O-N 3.08Å; G716-L719 PolarHBondContact O-N 2.93Å; G716-G720 PolarHBondContact O-N 2.61Å
717S64.8Low72.6Confident79 Ų7980 Ų8055%0.55247%0.47SS*.Hα-helixtrans-66.4-34.7173.550.90000112.9H715 G720 M721H715-S717 PolarHBondContact O-N 3.24Å; H715-S717 VanDerWaalsContact O-N 3.09Å; S717-G720 PolarHBondContact O-N 3.06Å; S717-M721 PolarHBondContact O-N 3.3Å; S717-M721 VanDerWaalsContact O-N 3.12Å
718V61.8Low71.8Confident42 Ų4273 Ų7326%0.25545%0.446SS..Hα-helixtrans-73.5-40.7177.5-1780000110.3A701 V714 H715 G720 M721 V722A701-V718 HydrophobicContact CB-CG2 4.45Å; V714-V718 HydrophobicContact CG1-CB 4.22Å; V714-V718 HydrophobicContact CG1-CG1 4.43Å; H715-V718 HydrophobicContact CB-CG2 4.29Å; H715-V718 WeakPolarHBondContact O-CB 3.18Å; H715-V718 PolarHBondContact O-N 3.32Å; V718-G720 VanDerWaalsContact C-N 3.28Å; V718-G720 PolarHBondContact O-N 3.2Å; V718-M721 HydrophobicContact CG2-CE 4.42Å; V718-M721 PolarHBondContact O-N 3.16Å; V718-V722 WeakPolarHBondContact O-CG2 3.45Å; V718-V722 PolarHBondContact O-N 2.81Å; V718-V722 VanDerWaalsContact O-N 3.11Å
719L56.8Low71.1Confident108 Ų10870.9 Ų70.957%0.56545%0.448SS*.Hα-helixtrans-61.5-39173.4-165.969.8000111.5H715 G716 V722 I723H715-L719 PolarHBondContact O-N 3.39Å; G716-L719 PolarHBondContact O-N 2.93Å; L719-V722 PolarHBondContact O-N 3.46Å; L719-I723 HydrophobicContact CG-CD1 4.16Å; L719-I723 WeakPolarHBondContact O-CG1 3.15Å; L719-I723 PolarHBondContact O-N 2.83Å; L719-I723 VanDerWaalsContact O-N 3.12Å
720G57.4Low70.4Confident43 Ų4375.5 Ų75.544%0.44347%0.472SS..Hα-helixtrans-62.5-39.217400000113.7G716 S717 V718 G724G716-G720 PolarHBondContact O-N 2.61Å; S717-G720 PolarHBondContact O-N 3.06Å; V718-G720 VanDerWaalsContact C-N 3.28Å; V718-G720 PolarHBondContact O-N 3.2Å; G720-G724 PolarHBondContact O-N 2.88Å
721M61.5Low69.7Low134 Ų13478.2 Ų78.266%0.6648%0.483SS*.Hα-helixtrans-68.7-37176.5-77.4-170.9-73.200112.9S717 V718 G725S717-M721 PolarHBondContact O-N 3.3Å; S717-M721 VanDerWaalsContact O-N 3.12Å; V718-M721 HydrophobicContact CG2-CE 4.42Å; V718-M721 PolarHBondContact O-N 3.16Å; M721-G725 PolarHBondContact O-N 2.89Å
722V63.7Low69.2Low91 Ų9181.7 Ų81.755%0.55250%0.496SS*.Hα-helixtrans-68.9-41.2177.8176.30000111.3V718 L719 T726V718-V722 WeakPolarHBondContact O-CG2 3.45Å; V718-V722 PolarHBondContact O-N 2.81Å; V718-V722 VanDerWaalsContact O-N 3.11Å; L719-V722 PolarHBondContact O-N 3.46Å; V722-T726 WeakPolarHBondContact O-CG2 3.34Å; V722-T726 PolarHBondContact O-N 2.67Å; V722-T726 VanDerWaalsContact O-N 3.11Å; V722-T726 PolarHBondContact O-OG1 2.99Å
723I64Low68.9Low105 Ų10580.2 Ų80.254%0.53849%0.492SS..Hα-helixtrans-70.2-40.2176.7-63.2170000110.9L719 T726 A727L719-I723 HydrophobicContact CG-CD1 4.16Å; L719-I723 WeakPolarHBondContact O-CG1 3.15Å; L719-I723 PolarHBondContact O-N 2.83Å; L719-I723 VanDerWaalsContact O-N 3.12Å; I723-T726 WeakPolarHBondContact CA-OG1 3.4Å; I723-T726 PolarHBondContact O-OG1 3Å; I723-A727 WeakPolarHBondContact O-CB 3.32Å; I723-A727 PolarHBondContact O-N 2.98Å; I723-A727 VanDerWaalsContact O-N 3.14Å
724G62.9Low68.8Low44 Ų4482.4 Ų82.445%0.45450%0.5SS..Hα-helixtrans-65.9-41.717600000113.1G720 A727 G728G720-G724 PolarHBondContact O-N 2.88Å; G724-A727 PolarHBondContact O-N 2.96Å; G724-G728 PolarHBondContact O-N 2.97Å
725G66.5Low68.6Low40 Ų4081 Ų8141%0.41249%0.494SS..Hα-helixtrans-65.4-42.5178.100000112.8M721 G728 V729M721-G725 PolarHBondContact O-N 2.89Å; G725-G728 PolarHBondContact O-N 3.27Å; G725-V729 WeakPolarHBondContact O-CG2 3.03Å; G725-V729 PolarHBondContact O-N 2.84Å
726T65.4Low68.8Low79 Ų7981.7 Ų81.749%0.48550%0.499SS..Hα-helixtrans-66.2-41.4176.943.30000112.3V722 I723 G728 V729 I730V722-T726 WeakPolarHBondContact O-CG2 3.34Å; V722-T726 PolarHBondContact O-N 2.67Å; V722-T726 VanDerWaalsContact O-N 3.11Å; V722-T726 PolarHBondContact O-OG1 2.99Å; I723-T726 WeakPolarHBondContact CA-OG1 3.4Å; I723-T726 PolarHBondContact O-OG1 3Å; T726-G728 VanDerWaalsContact C-N 3.35Å; T726-G728 PolarHBondContact O-N 3.15Å; T726-V729 PolarHBondContact O-N 2.7Å; T726-I730 VanDerWaalsContact O-CG1 3.31Å; T726-I730 WeakPolarHBondContact O-CG1 3.16Å; T726-I730 PolarHBondContact O-N 3.41Å; T726-I730 VanDerWaalsContact O-N 3.17Å
727A68.1Low69.4Low57 Ų5783.9 Ų83.947%0.47150%0.496SS..Hα-helixtrans-63-40.2173.300000112.3I723 G724 I730 F731I723-A727 WeakPolarHBondContact O-CB 3.32Å; I723-A727 PolarHBondContact O-N 2.98Å; I723-A727 VanDerWaalsContact O-N 3.14Å; G724-A727 PolarHBondContact O-N 2.96Å; A727-I730 PolarHBondContact O-N 3.31Å; A727-F731 PolarHBondContact O-N 3.31Å
728G70.2Confident69.9Low34 Ų3482.3 Ų82.335%0.35149%0.488SS..Hα-helixtrans-62.6-43.7177.500000113.2G724 G725 T726 F731 L732G724-G728 PolarHBondContact O-N 2.97Å; G725-G728 PolarHBondContact O-N 3.27Å; T726-G728 VanDerWaalsContact C-N 3.35Å; T726-G728 PolarHBondContact O-N 3.15Å; G728-F731 PolarHBondContact O-N 2.81Å; G728-L732 WeakPolarHBondContact O-CB 3.34Å; G728-L732 PolarHBondContact O-N 3.04Å
729V75.6Confident70.5Confident94 Ų9485.7 Ų85.757%0.5750%0.504SS*.Hα-helixtrans-66-39178172.90000111.6G725 T726 L732 T733G725-V729 WeakPolarHBondContact O-CG2 3.03Å; G725-V729 PolarHBondContact O-N 2.84Å; T726-V729 PolarHBondContact O-N 2.7Å; V729-L732 PolarHBondContact O-N 3.27Å; V729-T733 WeakPolarHBondContact O-CB 3.23Å; V729-T733 PolarHBondContact O-N 3.02Å; V729-T733 PolarHBondContact O-OG1 2.65Å
730I75.3Confident71.2Confident96 Ų9685.6 Ų85.649%0.49250%0.503SS..Hα-helixtrans-62.9-44.6174.6-67.4167.8000110.1T726 A727 L732 T733 F734T726-I730 VanDerWaalsContact O-CG1 3.31Å; T726-I730 WeakPolarHBondContact O-CG1 3.16Å; T726-I730 PolarHBondContact O-N 3.41Å; T726-I730 VanDerWaalsContact O-N 3.17Å; A727-I730 PolarHBondContact O-N 3.31Å; I730-L732 PolarHBondContact O-N 3.46Å; I730-T733 WeakPolarHBondContact CA-OG1 3.18Å; I730-T733 PolarHBondContact O-N 3.19Å; I730-T733 PolarHBondContact O-OG1 3.47Å; I730-F734 HydrophobicContact CG2-CD2 3.79Å; I730-F734 HydrophobicContact CG2-CE2 3.82Å; I730-F734 VanDerWaalsContact O-CD2 3.3Å; I730-F734 WeakPolarHBondContact O-CD2 3.34Å; I730-F734 PolarHBondContact O-N 3.43Å
731F75.9Confident71.6Confident158 Ų15888 Ų8869%0.69351%0.513SS*.Hα-helixtrans-65.3-39.8179.7-145.6-86.3000112.6A727 G728 S735A727-F731 PolarHBondContact O-N 3.31Å; G728-F731 PolarHBondContact O-N 2.81Å; F731-S735 WeakPolarHBondContact O-CB 3.17Å; F731-S735 PolarHBondContact O-N 3.35Å; F731-S735 PolarHBondContact O-OG 3.37Å
732L75.5Confident71.9Confident109 Ų10989.1 Ų89.157%0.57152%0.517SS*.Hα-helixtrans-66.3-41.9177.1-116.6143.7000112G728 V729 I730 S735 I736G728-L732 WeakPolarHBondContact O-CB 3.34Å; G728-L732 PolarHBondContact O-N 3.04Å; V729-L732 PolarHBondContact O-N 3.27Å; I730-L732 PolarHBondContact O-N 3.46Å; L732-S735 PolarHBondContact O-N 3.19Å; L732-I736 HydrophobicContact CD2-CD1 3.99Å; L732-I736 WeakPolarHBondContact O-CB 3.28Å; L732-I736 VanDerWaalsContact O-CG1 3.24Å; L732-I736 WeakPolarHBondContact O-CG1 2.93Å; L732-I736 PolarHBondContact O-N 3.05Å
733T79.6Confident71.5Confident69 Ų6994 Ų9442%0.42353%0.525SS..Hα-helixtrans-65.4-43176.740.80000112V729 I730 S735 I736 I737V729-T733 WeakPolarHBondContact O-CB 3.23Å; V729-T733 PolarHBondContact O-N 3.02Å; V729-T733 PolarHBondContact O-OG1 2.65Å; I730-T733 WeakPolarHBondContact CA-OG1 3.18Å; I730-T733 PolarHBondContact O-N 3.19Å; I730-T733 PolarHBondContact O-OG1 3.47Å; T733-S735 VanDerWaalsContact C-N 3.33Å; T733-S735 PolarHBondContact O-N 2.6Å; T733-I736 PolarHBondContact O-N 3.13Å; T733-I737 WeakPolarHBondContact O-CB 3.45Å; T733-I737 VanDerWaalsContact O-CG1 3.23Å; T733-I737 WeakPolarHBondContact O-CG1 3.48Å; T733-I737 PolarHBondContact O-N 3.31Å
734F80.1Confident71.1Confident138 Ų13894.3 Ų94.361%0.60553%0.534SS*.Hα-helixtrans-62.1-39.6173-87.5-72.3000112.7I730 I737 A738I730-F734 HydrophobicContact CG2-CD2 3.79Å; I730-F734 HydrophobicContact CG2-CE2 3.82Å; I730-F734 VanDerWaalsContact O-CD2 3.3Å; I730-F734 WeakPolarHBondContact O-CD2 3.34Å; I730-F734 PolarHBondContact O-N 3.43Å; F734-I737 PolarHBondContact O-N 3.06Å; F734-A738 WeakPolarHBondContact O-CB 3.17Å; F734-A738 PolarHBondContact O-N 3.35Å
735S76.7Confident70.8Confident51 Ų51104.2 Ų104.236%0.35756%0.558SS.*Hα-helixtrans-65.8-41.9177.9-59.70000111.9F731 L732 T733 A738 I739F731-S735 WeakPolarHBondContact O-CB 3.17Å; F731-S735 PolarHBondContact O-N 3.35Å; F731-S735 PolarHBondContact O-OG 3.37Å; L732-S735 PolarHBondContact O-N 3.19Å; T733-S735 VanDerWaalsContact C-N 3.33Å; T733-S735 PolarHBondContact O-N 2.6Å; S735-A738 PolarHBondContact O-N 2.58Å; S735-I739 WeakPolarHBondContact O-CD1 3.17Å; S735-I739 VanDerWaalsContact O-CG1 3.24Å; S735-I739 WeakPolarHBondContact O-CG1 3.17Å; S735-I739 PolarHBondContact O-N 3.49Å
736I78.9Confident69.9Low86 Ų86115.3 Ų115.344%0.44160%0.595SS.*Hα-helixtrans-65.1-43.3176.2-69.8166.2000110.8L732 T733 A738 I739 L740L732-I736 HydrophobicContact CD2-CD1 3.99Å; L732-I736 WeakPolarHBondContact O-CB 3.28Å; L732-I736 VanDerWaalsContact O-CG1 3.24Å; L732-I736 WeakPolarHBondContact O-CG1 2.93Å; L732-I736 PolarHBondContact O-N 3.05Å; T733-I736 PolarHBondContact O-N 3.13Å; I736-A738 VanDerWaalsContact C-N 3.34Å; I736-A738 PolarHBondContact O-N 3.43Å; I736-I739 PolarHBondContact O-N 2.75Å; I736-L740 HydrophobicContact CG2-CD1 3.84Å; I736-L740 HydrophobicContact CG2-CG 4.38Å; I736-L740 WeakPolarHBondContact O-CB 3.47Å; I736-L740 VanDerWaalsContact O-CG 3.29Å; I736-L740 WeakPolarHBondContact O-CG 3.21Å; I736-L740 PolarHBondContact O-N 2.82Å
737I77.4Confident70.1Confident104 Ų104117.1 Ų117.153%0.53360%0.6SS.*Hα-helixtrans-62.8-41.8177-68.9166.6000110.9T733 F734 L740 S741T733-I737 WeakPolarHBondContact O-CB 3.45Å; T733-I737 VanDerWaalsContact O-CG1 3.23Å; T733-I737 WeakPolarHBondContact O-CG1 3.48Å; T733-I737 PolarHBondContact O-N 3.31Å; F734-I737 PolarHBondContact O-N 3.06Å; I737-L740 PolarHBondContact O-N 3.1Å; I737-S741 WeakPolarHBondContact O-CB 2.93Å; I737-S741 PolarHBondContact O-N 3.48Å
738A74.9Confident70.2Confident46 Ų46120.3 Ų120.338%0.3861%0.607SS.*Hα-helixtrans-62-43.8176.200000111.9F734 S735 I736 S741 Q742F734-A738 WeakPolarHBondContact O-CB 3.17Å; F734-A738 PolarHBondContact O-N 3.35Å; S735-A738 PolarHBondContact O-N 2.58Å; I736-A738 VanDerWaalsContact C-N 3.34Å; I736-A738 PolarHBondContact O-N 3.43Å; A738-S741 PolarHBondContact O-N 3Å; A738-S741 PolarHBondContact O-OG 3.13Å; A738-Q742 PolarHBondContact O-N 3.46Å
739I74.9Confident70.2Confident114 Ų114125.1 Ų125.159%0.58562%0.621SS**Hα-helixtrans-64.6-40.8177-68.2165.2000111.3S735 I736 S741 Q742S735-I739 WeakPolarHBondContact O-CD1 3.17Å; S735-I739 VanDerWaalsContact O-CG1 3.24Å; S735-I739 WeakPolarHBondContact O-CG1 3.17Å; S735-I739 PolarHBondContact O-N 3.49Å; I736-I739 PolarHBondContact O-N 2.75Å; I739-S741 VanDerWaalsContact C-N 3.31Å; I739-S741 PolarHBondContact O-N 2.96Å; I739-Q742 PolarHBondContact O-N 2.9Å
740L70.1Confident69.9Low106 Ų106126.9 Ų126.956%0.55562%0.624SS**Hα-helixtrans-68.1-31177.1-70.7171.6000112.4I736 I737 Q742I736-L740 HydrophobicContact CG2-CD1 3.84Å; I736-L740 HydrophobicContact CG2-CG 4.38Å; I736-L740 WeakPolarHBondContact O-CB 3.47Å; I736-L740 VanDerWaalsContact O-CG 3.29Å; I736-L740 WeakPolarHBondContact O-CG 3.21Å; I736-L740 PolarHBondContact O-N 2.82Å; I737-L740 PolarHBondContact O-N 3.1Å; L740-Q742 VanDerWaalsContact C-N 3.29Å; L740-Q742 PolarHBondContact O-N 3.42Å
741S66.8Low69.5Low93 Ų93128.8 Ų128.865%0.6563%0.632SS**Hα-helixtrans-73.8-16.317776.40000114.4I737 A738 I739I737-S741 WeakPolarHBondContact O-CB 2.93Å; I737-S741 PolarHBondContact O-N 3.48Å; A738-S741 PolarHBondContact O-N 3Å; A738-S741 PolarHBondContact O-OG 3.13Å; I739-S741 VanDerWaalsContact C-N 3.31Å; I739-S741 PolarHBondContact O-N 2.96Å
742Q66.8Low69.1Low158 Ų158126.9 Ų126.974%0.73863%0.628SS**THydrogen-bonded Turntrans-96.50.6-179.7-71.8-173.5-1.200114.3A738 I739 L740 P744A738-Q742 PolarHBondContact O-N 3.46Å; I739-Q742 PolarHBondContact O-N 2.9Å; L740-Q742 VanDerWaalsContact C-N 3.29Å; L740-Q742 PolarHBondContact O-N 3.42Å; Q742-P744 VanDerWaalsContact O-CD 3.22Å; Q742-P744 WeakPolarHBondContact O-CD 3.29Å
743R56.7Low68.7Low193 Ų193128.1 Ų128.173%0.72863%0.632SS**  trans-73.4114.8173.8-85.2-174.6174.4178.3-0.6110.2R745R743-R745 PolarHBondContact O-N 2.89Å
744P54.6Low67.8Low111 Ų111132.7 Ų132.772%0.72165%0.649SS**  trans-68.9125.9175.128.6-31.1000108.7Q742 K746Q742-P744 VanDerWaalsContact O-CD 3.22Å; Q742-P744 WeakPolarHBondContact O-CD 3.29Å; P744-K746 PolarHBondContact O-N 3.24Å; P744-K746 VanDerWaalsContact O-N 3.1Å
745R56.8Low66.8Low253 Ų253132.3 Ų132.396%0.95565%0.652SS**  trans-58.7113.5169.9-77-178.8176.2172-1.5108.6R743R743-R745 PolarHBondContact O-N 2.89Å
746K46.9Very low65.9Low272 Ų272139.6 Ų139.6100%1.18368%0.679SS**  trans-132.20162.9-86.5-167.8175.4-1770108.8P744P744-K746 PolarHBondContact O-N 3.24Å; P744-K746 VanDerWaalsContact O-N 3.1Å

Retrieved 746 of 746 residues in 1607.8 ms (Link to these results)