A0A2K5W9G2_MACFA Loading...

Sodium-dependent lysophosphatidylcholine symporter 1

AlphaFold DB , UniProt , Accession A0A2K5W9G2, Species MACFA (Macaca fascicularis, Crab-eating macaque), Gene MFSD2A, Length 543 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35.6	Very low	27.9	Very low	239 Å²	239	137.1 Å²	137.1	100%	1.177	87%	0.871	S	S	*	*				0	100.5	0	-74.3	172.4	166.9	0	0	105.8
2	A	31	Very low	27.8	Very low	101 Å²	101	134.3 Å²	134.3	84%	0.835	87%	0.869	S	S	*	*				55.4	132.2	91	0	0	0	0	0	111.5
3	K	28.7	Very low	27.9	Very low	204 Å²	204	131.2 Å²	131.2	89%	0.887	86%	0.863	S	S	*	*			cis	176.5	153	2.6	180	-179.8	-178.7	-177	0	105.6
4	G	26.9	Very low	27.9	Very low	64 Å²	64	127.4 Å²	127.4	66%	0.66	86%	0.859	S	S	*	*			trans	99.1	115	153.7	0	0	0	0	0	115.4
5	E	28.6	Very low	27.9	Very low	199 Å²	199	130.4 Å²	130.4	93%	0.93	86%	0.862	S	S	*	*				77.6	129	58.4	-75.6	-171.1	131.6	0	0	115.7
6	G	26.8	Very low	28.1	Very low	81 Å²	81	131.8 Å²	131.8	84%	0.835	86%	0.857	S	S	*	*			trans	103.6	137.3	160.7	0	0	0	0	0	115.6
7	A	26	Very low	28.3	Very low	99 Å²	99	129.8 Å²	129.8	82%	0.818	85%	0.845	S	S	*	*			cis	-176.8	136.4	-17.5	0	0	0	0	0	105.9
8	E	28.2	Very low	28.5	Very low	195 Å²	195	128.6 Å²	128.6	91%	0.911	84%	0.835	S	S	*	*			trans	2.6	137	156.4	-62	179.5	152.8	0	0	121.5
9	S	25.5	Very low	28.6	Very low	123 Å²	123	126.6 Å²	126.6	86%	0.86	82%	0.824	S	S	*	*				-158	117.9	122.5	-170.4	0	0	0	0	110.2
10	G	24.8	Very low	28.8	Very low	75 Å²	75	127.8 Å²	127.8	77%	0.773	82%	0.821	S	S	*	*			trans	-85.8	160.6	178.4	0	0	0	0	0	113.4
11	S	25.1	Very low	29	Very low	128 Å²	128	128.9 Å²	128.9	90%	0.895	82%	0.82	S	S	*	*			trans	-146	126.9	152.1	-164.5	0	0	0	0	109.6	A13	S11-A13 PolarHBondContact O-N 2.93Å
12	A	26	Very low	28.7	Very low	103 Å²	103	125.8 Å²	125.8	85%	0.851	80%	0.802	S	S	*	*			trans	-76.5	114.6	-164	0	0	0	0	0	112.5
13	A	29.8	Very low	28.7	Very low	95 Å²	95	125.2 Å²	125.2	79%	0.785	80%	0.798	S	S	*	*			trans	-86.4	114.1	155.7	0	0	0	0	0	107.9	S11 L15	S11-A13 PolarHBondContact O-N 2.93Å; A13-L15 PolarHBondContact O-N 3.06Å
14	G	27	Very low	28.9	Very low	78 Å²	78	121.7 Å²	121.7	80%	0.804	79%	0.793	S	S	*	*	P	Polyproline II helix	trans	-55.5	126.3	-179.3	0	0	0	0	0	112.5	L16	G14-L16 PolarHBondContact O-N 3.17Å
15	L	29.3	Very low	29.1	Very low	172 Å²	172	127.6 Å²	127.6	90%	0.901	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-64.8	117	-177.6	-72.7	142.1	0	0	0	112.2	A13	A13-L15 PolarHBondContact O-N 3.06Å
16	L	30.3	Very low	29	Very low	152 Å²	152	129.1 Å²	129.1	80%	0.796	80%	0.801	S	S	*	*	P	Polyproline II helix	trans	-84.3	131.7	150	-80	162.4	0	0	0	107.4	G14 T18	G14-L16 PolarHBondContact O-N 3.17Å; L16-T18 PolarHBondContact O-N 3.35Å; L16-T18 VanDerWaalsContact O-N 3.13Å
17	P	31.7	Very low	29	Very low	99 Å²	99	131.9 Å²	131.9	64%	0.643	80%	0.804	S	S	*	*			trans	-72.8	109.4	173.2	15.4	-9.4	0	0	0	109.7	S19	P17-S19 PolarHBondContact O-N 2.97Å
18	T	32.5	Very low	29.2	Very low	108 Å²	108	131 Å²	131	66%	0.663	80%	0.797	S	S	*	*	G	3₁₀ helix	trans	-66.2	5.4	175.8	-23.3	0	0	0	0	113.6	L16 I20	L16-T18 PolarHBondContact O-N 3.35Å; L16-T18 VanDerWaalsContact O-N 3.13Å; T18-I20 PolarHBondContact O-N 2.95Å
19	S	29.8	Very low	29.1	Very low	91 Å²	91	131 Å²	131	64%	0.636	80%	0.797	S	S	*	*	G	3₁₀ helix	trans	-77.1	-14.1	-171.6	55.2	0	0	0	0	114.8	P17	P17-S19 PolarHBondContact O-N 2.97Å
20	I	33.3	Very low	29.3	Very low	150 Å²	150	131.5 Å²	131.5	77%	0.769	80%	0.795	S	S	*	*	G	3₁₀ helix	trans	-87.1	-16.8	-177.7	-58.4	178.3	0	0	0	112.4	T18	T18-I20 PolarHBondContact O-N 2.95Å
21	L	32.9	Very low	29.4	Very low	151 Å²	151	137 Å²	137	79%	0.791	80%	0.798	S	S	*	*	S	Bend	trans	-97.5	-5.6	-173.5	-83.6	163.5	0	0	0	115.7
22	Q	28.3	Very low	29.5	Very low	173 Å²	173	140.6 Å²	140.6	81%	0.808	80%	0.797	S	S	*	*	S	Bend	trans	-114.4	5.8	-174.3	-93.8	-178.4	-20.8	0	0	115.9	T24	Q22-T24 VanDerWaalsContact C-N 3.33Å; Q22-T24 PolarHBondContact O-N 2.87Å
23	A	30.6	Very low	29.8	Very low	89 Å²	89	143.6 Å²	143.6	74%	0.736	79%	0.793	S	S	*	*			trans	-85.9	12.5	-177.8	0	0	0	0	0	115.3
24	T	33	Very low	29.8	Very low	130 Å²	130	144.7 Å²	144.7	80%	0.798	79%	0.792	S	S	*	*			trans	-102.6	26.1	-170.2	-30.5	0	0	0	0	115.7	Q22	Q22-T24 VanDerWaalsContact C-N 3.33Å; Q22-T24 PolarHBondContact O-N 2.87Å
25	E	31.8	Very low	30.1	Very low	188 Å²	188	151 Å²	151	88%	0.879	80%	0.798	S	S	*	*			trans	-134.2	73.6	171	-70.8	-170.1	167.3	0	0	112.4
26	R	26.4	Very low	30.6	Very low	232 Å²	232	150.5 Å²	150.5	88%	0.875	79%	0.788	S	S	*	*			trans	-141.1	132.7	151.1	-66.5	-170.1	-152.4	-175.3	8.2	109.4	A28	R26-A28 VanDerWaalsContact C-N 3.31Å; R26-A28 PolarHBondContact O-N 3.13Å
27	P	27.4	Very low	31	Very low	138 Å²	138	152.9 Å²	152.9	90%	0.896	79%	0.792	S	S	*	*			trans	-78.2	84.6	176	31.6	-30.4	0	0	0	108.9
28	A	30.1	Very low	32	Very low	82 Å²	82	155.8 Å²	155.8	68%	0.678	80%	0.795	S	S	*	*			trans	-79.3	125.9	166.4	0	0	0	0	0	108.7	R26 V30	R26-A28 VanDerWaalsContact C-N 3.31Å; R26-A28 PolarHBondContact O-N 3.13Å; A28-V30 PolarHBondContact O-N 3.41Å
29	Q	25.6	Very low	33.2	Very low	195 Å²	195	157.5 Å²	157.5	91%	0.911	80%	0.795	S	S	*	*			trans	-53.5	112.8	176.5	-72	-176	-18.7	0	0	110.5	K31	Q29-K31 PolarHBondContact O-N 2.77Å
30	V	29.7	Very low	35.3	Very low	132 Å²	132	160.2 Å²	160.2	80%	0.8	80%	0.798	S	S	*	*			trans	-72.5	94	175.9	-179.3	0	0	0	0	108.5	A28 K32	A28-V30 PolarHBondContact O-N 3.41Å; V30-K32 PolarHBondContact O-N 3.44Å
31	K	27.1	Very low	37.5	Very low	192 Å²	192	154.4 Å²	154.4	84%	0.835	77%	0.768	S	S	*	*			trans	-59.7	113.3	157.7	-126.1	176.5	-178.7	179.9	0	106	Q29 E33	Q29-K31 PolarHBondContact O-N 2.77Å; K31-E33 VanDerWaalsContact C-N 3.32Å; K31-E33 PolarHBondContact O-N 3.25Å
32	K	27.5	Very low	40.2	Very low	202 Å²	202	150.6 Å²	150.6	88%	0.878	75%	0.754	S	S	*	*			trans	-64.2	94.2	173.4	-83	-179.1	177.7	171.9	0	108.4	V30	V30-K32 PolarHBondContact O-N 3.44Å
33	E	31.4	Very low	43.1	Very low	167 Å²	167	146.7 Å²	146.7	78%	0.78	74%	0.742	S	S	*	*			trans	-60.7	146.3	162.7	-77.4	-171.3	159.3	0	0	110	K31 K35	K31-E33 VanDerWaalsContact C-N 3.32Å; K31-E33 PolarHBondContact O-N 3.25Å; E33-K35 PolarHBondContact O-N 3Å
34	P	30.6	Very low	45.9	Very low	118 Å²	118	146.3 Å²	146.3	77%	0.766	73%	0.733	S	S	*	*			trans	-61.3	124.7	175.3	25.7	-31.5	0	0	0	109	K36	P34-K36 PolarHBondContact O-N 3.47Å
35	K	33.1	Very low	48.6	Very low	210 Å²	210	141.9 Å²	141.9	91%	0.913	71%	0.707	S	S	*	*			trans	-45.6	105.2	175.3	-75.8	177	175.1	175.9	0	109.9	E33 K37	E33-K35 PolarHBondContact O-N 3Å; K35-K37 PolarHBondContact O-N 3.12Å; K35-K37 VanDerWaalsContact O-N 3.12Å
36	K	39.8	Very low	51.6	Low	161 Å²	161	133.9 Å²	133.9	70%	0.7	67%	0.67	S	S	*	*			trans	-48.3	121.3	166.7	-89.1	176.8	177.6	169.4	0	107.3	P34 K38	P34-K36 PolarHBondContact O-N 3.47Å; K36-K38 PolarHBondContact O-N 3.23Å
37	K	38.3	Very low	54.8	Low	203 Å²	203	126.8 Å²	126.8	88%	0.883	65%	0.649	S	S	*	*			trans	-53.9	115.2	174.2	-88.9	178.7	174	176.5	0	107.2	K35 Q39	K35-K37 PolarHBondContact O-N 3.12Å; K35-K37 VanDerWaalsContact O-N 3.12Å; K37-Q39 PolarHBondContact O-N 2.87Å
38	K	52.3	Low	58	Low	160 Å²	160	121.1 Å²	121.1	70%	0.696	61%	0.612	S	S	*	*			trans	-52.4	115.1	168.2	-70.5	-178	176.5	-175.7	0	106.8	K36 Q40	K36-K38 PolarHBondContact O-N 3.23Å; K38-Q40 PolarHBondContact O-N 3.48Å
39	Q	58.6	Low	61.1	Low	144 Å²	144	117.2 Å²	117.2	67%	0.673	58%	0.579	S	S	*	*			trans	-68.8	84.7	176	-82.4	175.6	-22.5	0	0	108.3	K37	K37-Q39 PolarHBondContact O-N 2.87Å
40	Q	73.4	Confident	64.5	Low	147 Å²	147	107.9 Å²	107.9	69%	0.687	54%	0.536	S	S	*	.	P	Polyproline II helix	trans	-74.4	135.4	172.4	-70.7	178.2	-26.3	0	0	108.7	K38	K38-Q40 PolarHBondContact O-N 3.48Å
41	L	80.5	Confident	67.6	Low	29 Å²	29	103.9 Å²	103.9	15%	0.152	51%	0.51	C	S	.	.	P	Polyproline II helix	trans	-71.4	132.6	176.4	-75	172.5	0	0	0	109.4	K46 I185 E191	L41-K46 HydrophobicContact CB-CD 4.48Å; L41-K46 VanDerWaalsContact CB-CE 3.48Å; L41-K46 HydrophobicContact CB-CG 4.1Å; L41-K46 WeakPolarHBondContact O-CE 3.37Å; L41-I185 HydrophobicContact CD1-CD1 4.12Å; L41-I185 HydrophobicContact CD1-CG1 3.89Å; L41-I185 HydrophobicContact CD1-CG2 4.09Å; L41-I185 HydrophobicContact CD2-CG1 4Å; L41-E191 HydrophobicContact CD1-CB 4.25Å; L41-E191 PolarHBondContact N-OE2 3.27Å; L41-E191 VanDerWaalsContact N-OE2 3.16Å
42	S	88.6	Confident	70.8	Confident	71 Å²	71	94.8 Å²	94.8	50%	0.497	47%	0.47	S	S	.	.	P	Polyproline II helix	trans	-61.2	144.6	172.2	-179.5	0	0	0	0	110.4	C44 S45 K46	S42-C44 PolarHBondContact O-N 3.36Å; S42-C44 PolarHBondContact OG-N 3.03Å; S42-S45 PolarHBondContact O-N 3.47Å; S42-K46 PolarHBondContact O-N 3.01Å
43	V	88.8	Confident	73.9	Confident	90 Å²	90	85.1 Å²	85.1	55%	0.545	43%	0.428	S	S	.	.	H	α-helix	trans	-56.1	-36.9	175.2	179	0	0	0	0	110.9	K46 L47	V43-K46 PolarHBondContact O-N 2.93Å; V43-L47 WeakPolarHBondContact O-CB 3.32Å; V43-L47 PolarHBondContact O-N 3.27Å
44	C	90.3	Very high	76.9	Confident	81 Å²	81	77.6 Å²	77.6	55%	0.547	40%	0.395	S	S	.	.	H	α-helix	trans	-60.5	-47.3	175.6	-175	0	0	0	0	111.5	S42 K46 L47 C48	S42-C44 PolarHBondContact O-N 3.36Å; S42-C44 PolarHBondContact OG-N 3.03Å; C44-K46 VanDerWaalsContact C-N 3.32Å; C44-K46 PolarHBondContact O-N 3.24Å; C44-L47 PolarHBondContact O-N 2.96Å; C44-L47 VanDerWaalsContact O-N 3.16Å; C44-C48 PolarHBondContact O-N 2.66Å; C44-C48 PolarHBondContact O-SG 3.27Å
45	S	90.1	Very high	80	Confident	37 Å²	37	72.1 Å²	72.1	26%	0.259	36%	0.359	S	S	.	.	H	α-helix	trans	-63.5	-36.6	177.3	-56.4	0	0	0	0	112.5	S42 Y49	S42-S45 PolarHBondContact O-N 3.47Å; S45-Y49 WeakPolarHBondContact O-CB 3.34Å; S45-Y49 PolarHBondContact O-N 3.07Å
46	K	93.7	Very high	82.8	Confident	21 Å²	21	64.2 Å²	64.2	9%	0.091	32%	0.324	C	S	.	.	H	α-helix	trans	-65.5	-40	174	-65.8	-179.4	-171.8	-177.1	0	111.9	L41 S42 V43 C44 Y49 A50 E191 S194 Y198	L41-K46 HydrophobicContact CB-CD 4.48Å; L41-K46 VanDerWaalsContact CB-CE 3.48Å; L41-K46 HydrophobicContact CB-CG 4.1Å; L41-K46 WeakPolarHBondContact O-CE 3.37Å; S42-K46 PolarHBondContact O-N 3.01Å; V43-K46 PolarHBondContact O-N 2.93Å; C44-K46 VanDerWaalsContact C-N 3.32Å; C44-K46 PolarHBondContact O-N 3.24Å; K46-Y49 PolarHBondContact O-N 3.33Å; K46-A50 WeakPolarHBondContact O-CB 3.48Å; K46-A50 PolarHBondContact O-N 2.88Å; K46-E191 WeakPolarHBondContact CE-OE2 3.27Å; K46-E191 IonicContact NZ-OE1 3.46Å; K46-E191 IonicContact NZ-OE2 2.76Å; K46-E191 PolarHBondContact NZ-OE2 3.03Å; K46-S194 WeakPolarHBondContact CE-OG 3.5Å; K46-S194 PolarHBondContact NZ-OG 3.12Å; K46-Y198 HydrophobicContact CB-CD2 4.27Å; K46-Y198 HydrophobicContact CB-CG 4.36Å; K46-Y198 HydrophobicContact CD-CD2 4.36Å; K46-Y198 HydrophobicContact CD-CE2 4.27Å
47	L	94.6	Very high	85.3	Confident	83 Å²	83	58.4 Å²	58.4	44%	0.435	30%	0.299	S	S	.	.	H	α-helix	trans	-69.1	-42.7	177.1	-173.1	64.3	0	0	0	111.7	V43 C44 Y49 A50 L51	V43-L47 WeakPolarHBondContact O-CB 3.32Å; V43-L47 PolarHBondContact O-N 3.27Å; C44-L47 PolarHBondContact O-N 2.96Å; C44-L47 VanDerWaalsContact O-N 3.16Å; L47-Y49 VanDerWaalsContact C-N 3.3Å; L47-Y49 PolarHBondContact O-N 3.39Å; L47-A50 PolarHBondContact O-N 3.12Å; L47-A50 VanDerWaalsContact O-N 3.16Å; L47-L51 HydrophobicContact CG-CD1 4.41Å; L47-L51 WeakPolarHBondContact O-CG 2.83Å; L47-L51 PolarHBondContact O-N 2.97Å
48	C	94.5	Very high	87.9	Confident	18 Å²	18	48.9 Å²	48.9	12%	0.122	26%	0.258	C	S	.	.	H	α-helix	trans	-60.6	-41.3	173.8	-64.9	0	0	0	0	111.5	C44 I272 V277	C44-C48 PolarHBondContact O-N 2.66Å; C44-C48 PolarHBondContact O-SG 3.27Å; C48-I272 HydrophobicContact CB-CG2 4.01Å; C48-V277 HydrophobicContact CB-CG2 4.2Å
49	Y	95.1	Very high	89.9	Confident	0 Å²	0	41.3 Å²	41.3	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-60.9	-46.9	172	173.9	-110.6	0	0	0	111.6	S45 K46 L47 L51 G52 Y178 L181 T182 I185 A195 R199 L273	S45-Y49 WeakPolarHBondContact O-CB 3.34Å; S45-Y49 PolarHBondContact O-N 3.07Å; K46-Y49 PolarHBondContact O-N 3.33Å; L47-Y49 VanDerWaalsContact C-N 3.3Å; L47-Y49 PolarHBondContact O-N 3.39Å; Y49-L51 PolarHBondContact O-N 3.38Å; Y49-G52 PolarHBondContact O-N 3.39Å; Y49-G52 VanDerWaalsContact O-N 3.14Å; Y49-Y178 AromaticContact CD2-CE2 3.88Å; Y49-Y178 HydrophobicContact CD2-CE2 3.88Å; Y49-Y178 HydrophobicContact CE2-CD2 4.13Å; Y49-Y178 AromaticContact CE2-CE2 3.58Å; Y49-Y178 HydrophobicContact CE2-CE2 3.58Å; Y49-Y178 WeakPolarHBondContact O-CE2 3.48Å; Y49-Y178 PolarHBondContact O-OH 2.76Å; Y49-Y178 PolarHBondContact OH-O 3.33Å; Y49-L181 HydrophobicContact CD2-CD2 3.99Å; Y49-L181 HydrophobicContact CD2-CG 4.44Å; Y49-L181 HydrophobicContact CE2-CB 4.11Å; Y49-L181 HydrophobicContact CE2-CD2 4.03Å; Y49-L181 HydrophobicContact CE2-CG 4.21Å; Y49-T182 PolarHBondContact OH-OG1 3.36Å; Y49-I185 HydrophobicContact CD2-CD1 4.2Å; Y49-I185 HydrophobicContact CG-CD1 3.92Å; Y49-A195 HydrophobicContact CD1-CB 3.88Å; Y49-A195 HydrophobicContact CE1-CB 4.06Å; Y49-R199 HydrophobicContact CE1-CB 4.01Å; Y49-R199 WeakPolarHBondContact OH-CD 3.31Å; Y49-L273 HydrophobicContact CD2-CD1 4.37Å
50	A	95.5	Very high	91.4	Very high	0 Å²	0	36.1 Å²	36.1	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-64.6	-37.9	-178.8	0	0	0	0	0	113.6	K46 L47 G52 G53 Y178 Y198 V202	K46-A50 WeakPolarHBondContact O-CB 3.48Å; K46-A50 PolarHBondContact O-N 2.88Å; L47-A50 PolarHBondContact O-N 3.12Å; L47-A50 VanDerWaalsContact O-N 3.16Å; A50-G52 PolarHBondContact O-N 2.63Å; A50-G53 PolarHBondContact O-N 3.08Å; A50-Y178 PolarHBondContact O-OH 3.25Å; A50-Y198 VanDerWaalsContact CB-C 3.41Å; A50-Y198 WeakPolarHBondContact CB-O 3.22Å; A50-V202 HydrophobicContact CB-CB 4.17Å; A50-V202 HydrophobicContact CB-CG2 3.68Å; A50-V202 VanDerWaalsContact O-CG1 3.29Å; A50-V202 WeakPolarHBondContact O-CG1 3.28Å
51	L	95.8	Very high	92	Very high	48 Å²	48	29.9 Å²	29.9	25%	0.251	18%	0.182	S	C	.	.	H	α-helix	trans	-59.1	-26.9	174.8	-77.2	167.8	0	0	0	112.9	L47 Y49 G53 A54 P55 V202 C269 I272	L47-L51 HydrophobicContact CG-CD1 4.41Å; L47-L51 WeakPolarHBondContact O-CG 2.83Å; L47-L51 PolarHBondContact O-N 2.97Å; Y49-L51 PolarHBondContact O-N 3.38Å; L51-G53 PolarHBondContact O-N 3.37Å; L51-A54 PolarHBondContact O-N 3.23Å; L51-P55 WeakPolarHBondContact O-CD 3.36Å; L51-V202 HydrophobicContact CD2-CG1 4.42Å; L51-C269 WeakPolarHBondContact O-CB 3.29Å; L51-I272 HydrophobicContact CB-CG2 4.36Å; L51-I272 HydrophobicContact CD1-CD1 4.11Å; L51-I272 HydrophobicContact CD1-CG2 3.77Å
52	G	94.1	Very high	92.4	Very high	0 Å²	0	28.5 Å²	28.5	0%	0	18%	0.175	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.7	-21.2	171.9	0	0	0	0	0	114.9	Y49 A50 P55 F174	Y49-G52 PolarHBondContact O-N 3.39Å; Y49-G52 VanDerWaalsContact O-N 3.14Å; A50-G52 PolarHBondContact O-N 2.63Å; G52-P55 WeakPolarHBondContact O-CD 3.45Å; G52-F174 WeakPolarHBondContact O-CE1 3.45Å
53	G	93	Very high	92.4	Very high	0 Å²	0	25.4 Å²	25.4	0%	0	15%	0.153	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.6	-22	-178.5	0	0	0	0	0	114.1	A50 L51 Y56 Y178	A50-G53 PolarHBondContact O-N 3.08Å; L51-G53 PolarHBondContact O-N 3.37Å; G53-Y56 PolarHBondContact O-N 2.83Å; G53-Y178 WeakPolarHBondContact CA-OH 3.1Å; G53-Y178 PolarHBondContact N-OH 3.09Å
54	A	94.8	Very high	92.1	Very high	9 Å²	9	22.9 Å²	22.9	7%	0.074	15%	0.145	C	C	.	.	H	α-helix	trans	-59.8	-44.1	-178.7	0	0	0	0	0	113.9	L51 Y56 Q57 V58 V202	L51-A54 PolarHBondContact O-N 3.23Å; A54-Y56 VanDerWaalsContact C-N 3.32Å; A54-Y56 PolarHBondContact O-N 2.95Å; A54-Q57 PolarHBondContact O-N 3.14Å; A54-V58 WeakPolarHBondContact O-CB 3.41Å; A54-V58 WeakPolarHBondContact O-CG2 3.23Å; A54-V58 PolarHBondContact O-N 3.18Å; A54-V202 HydrophobicContact CB-CG1 3.88Å
55	P	94.7	Very high	91.3	Very high	2 Å²	2	23.1 Å²	23.1	1%	0.013	14%	0.137	C	C	.	.	H	α-helix	trans	-52.6	-45.3	-179.8	-31.2	38.2	0	0	0	114.3	L51 G52 T59 F174 Y266 C269	L51-P55 WeakPolarHBondContact O-CD 3.36Å; G52-P55 WeakPolarHBondContact O-CD 3.45Å; P55-T59 WeakPolarHBondContact O-CB 3.15Å; P55-T59 WeakPolarHBondContact O-CG2 3.48Å; P55-T59 PolarHBondContact O-N 3.35Å; P55-T59 PolarHBondContact O-OG1 2.96Å; P55-F174 HydrophobicContact CB-CE1 4.33Å; P55-F174 HydrophobicContact CB-CZ 4.35Å; P55-F174 HydrophobicContact CG-CE1 4.47Å; P55-F174 HydrophobicContact CG-CZ 4.16Å; P55-Y266 HydrophobicContact CB-CD1 4.04Å; P55-Y266 HydrophobicContact CB-CD2 3.53Å; P55-Y266 HydrophobicContact CB-CE1 4.08Å; P55-Y266 HydrophobicContact CB-CE2 3.6Å; P55-Y266 HydrophobicContact CB-CG 3.73Å; P55-Y266 HydrophobicContact CG-CD1 4.45Å; P55-Y266 HydrophobicContact CG-CG 4.38Å; P55-C269 HydrophobicContact CG-CB 3.5Å; P55-C269 VanDerWaalsContact CG-CB 3.5Å
56	Y	92.6	Very high	91	Very high	45 Å²	45	22.4 Å²	22.4	18%	0.176	13%	0.129	C	C	.	.	H	α-helix	trans	-61.4	-48.8	179.4	176.4	-111	0	0	0	111.3	G53 A54 T59 G60 V171 H175	G53-Y56 PolarHBondContact O-N 2.83Å; A54-Y56 VanDerWaalsContact C-N 3.32Å; A54-Y56 PolarHBondContact O-N 2.95Å; Y56-T59 PolarHBondContact O-OG1 3.43Å; Y56-G60 WeakPolarHBondContact O-CA 3.49Å; Y56-G60 PolarHBondContact O-N 3.07Å; Y56-V171 HydrophobicContact CD2-CG1 3.46Å; Y56-V171 VanDerWaalsContact CD2-CG1 3.46Å; Y56-V171 HydrophobicContact CE2-CG1 3.87Å; Y56-H175 AromaticContact CD1-CD2 3.5Å; Y56-H175 VanDerWaalsContact CD1-CD2 3.5Å; Y56-H175 WeakPolarHBondContact CD1-CD2 3.4Å; Y56-H175 AromaticContact CD1-NE2 3.71Å; Y56-H175 HydrophobicContact CD2-CB 3.87Å; Y56-H175 AromaticContact CD2-CD2 3.92Å; Y56-H175 AromaticContact CD2-CG 3.83Å; Y56-H175 AromaticContact CE1-CD2 3.89Å; Y56-H175 AromaticContact CE1-NE2 3.73Å; Y56-H175 HydrophobicContact CE2-CB 4.27Å; Y56-H175 HydrophobicContact CG-CB 4.25Å; Y56-H175 AromaticContact CG-CD2 3.52Å; Y56-H175 AromaticContact CG-CG 3.93Å
57	Q	92.5	Very high	90.6	Very high	39 Å²	39	21.5 Å²	21.5	18%	0.182	13%	0.126	C	C	.	.	H	α-helix	trans	-72.9	-41.6	-176.5	-62.7	-65.2	2.4	0	0	113.1	A54 C61 E203	A54-Q57 PolarHBondContact O-N 3.14Å; Q57-C61 VanDerWaalsContact O-CB 3.28Å; Q57-C61 WeakPolarHBondContact O-CB 3.39Å; Q57-C61 PolarHBondContact O-N 3.5Å; Q57-C61 PolarHBondContact O-SG 2.9Å; Q57-E203 WeakPolarHBondContact CB-O 3.37Å; Q57-E203 HydrophobicContact CG-CB 3.61Å; Q57-E203 HydrophobicContact CG-CG 3.65Å; Q57-E203 PolarHBondContact NE2-OE2 3.37Å; Q57-E203 VanDerWaalsContact NE2-OE2 3.13Å
58	V	93.1	Very high	89.9	Confident	2 Å²	2	22.7 Å²	22.7	1%	0.012	13%	0.129	C	C	.	.	H	α-helix	trans	-61.4	-49	179.8	174.3	0	0	0	0	110.4	A54 A62 G206 I262	A54-V58 WeakPolarHBondContact O-CB 3.41Å; A54-V58 WeakPolarHBondContact O-CG2 3.23Å; A54-V58 PolarHBondContact O-N 3.18Å; V58-A62 WeakPolarHBondContact O-CB 3.49Å; V58-A62 PolarHBondContact O-N 3.25Å; V58-A62 VanDerWaalsContact O-N 3.16Å; V58-G206 VanDerWaalsContact CG2-O 3.28Å; V58-G206 WeakPolarHBondContact CG2-O 3.48Å; V58-I262 HydrophobicContact CG1-CB 4.33Å; V58-I262 HydrophobicContact CG1-CD1 4.37Å; V58-I262 HydrophobicContact CG1-CG1 3.89Å; V58-I262 HydrophobicContact CG1-CG2 3.74Å
59	T	93.9	Very high	89.1	Confident	1 Å²	1	25.3 Å²	25.3	1%	0.006	14%	0.141	C	C	.	.	H	α-helix	trans	-71.3	-41.8	179.7	55.1	0	0	0	0	112.3	P55 Y56 C61 A62 L63 Y143 F167 I262 Y266	P55-T59 WeakPolarHBondContact O-CB 3.15Å; P55-T59 WeakPolarHBondContact O-CG2 3.48Å; P55-T59 PolarHBondContact O-N 3.35Å; P55-T59 PolarHBondContact O-OG1 2.96Å; Y56-T59 PolarHBondContact O-OG1 3.43Å; T59-C61 PolarHBondContact O-N 3.34Å; T59-A62 PolarHBondContact O-N 3.23Å; T59-L63 WeakPolarHBondContact O-CG 3.45Å; T59-L63 PolarHBondContact O-N 3.43Å; T59-Y143 HydrophobicContact CG2-CD2 3.95Å; T59-Y143 HydrophobicContact CG2-CE2 3.78Å; T59-Y143 HydrophobicContact CG2-CG 4.4Å; T59-F167 HydrophobicContact CG2-CZ 4.1Å; T59-I262 HydrophobicContact CG2-CG2 3.59Å; T59-Y266 HydrophobicContact CG2-CD2 3.88Å; T59-Y266 HydrophobicContact CG2-CE2 4.37Å
60	G	90.3	Very high	88.4	Confident	35 Å²	35	25.3 Å²	25.3	36%	0.361	14%	0.141	S	C	.	.	H	α-helix	trans	-60.6	-42.2	177.6	0	0	0	0	0	112.7	Y56 G64	Y56-G60 WeakPolarHBondContact O-CA 3.49Å; Y56-G60 PolarHBondContact O-N 3.07Å; G60-G64 WeakPolarHBondContact O-CA 3.23Å; G60-G64 PolarHBondContact O-N 3.45Å
61	C	86.6	Confident	87.7	Confident	16 Å²	16	25.4 Å²	25.4	11%	0.108	14%	0.141	C	C	.	.	H	α-helix	trans	-69.6	-41.5	176.9	-64.7	0	0	0	0	111.9	Q57 T59 L63 G64 F65 T207	Q57-C61 VanDerWaalsContact O-CB 3.28Å; Q57-C61 WeakPolarHBondContact O-CB 3.39Å; Q57-C61 PolarHBondContact O-N 3.5Å; Q57-C61 PolarHBondContact O-SG 2.9Å; T59-C61 PolarHBondContact O-N 3.34Å; C61-L63 PolarHBondContact O-N 3.17Å; C61-G64 PolarHBondContact O-N 2.9Å; C61-F65 HydrophobicContact CB-CD2 4.41Å; C61-F65 HydrophobicContact CB-CE2 4.4Å; C61-F65 VanDerWaalsContact O-CD2 3.24Å; C61-F65 WeakPolarHBondContact O-CD2 3.18Å; C61-F65 PolarHBondContact O-N 3.48Å; C61-T207 HydrophobicContact CB-CG2 4.49Å; C61-T207 WeakPolarHBondContact SG-CG2 3Å; C61-T207 PolarHBondContact SG-OG1 3.35Å; C61-T207 VanDerWaalsContact SG-OG1 3.37Å
62	A	88	Confident	86.6	Confident	0 Å²	0	24.8 Å²	24.8	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-60.4	-46.2	176.6	0	0	0	0	0	111.7	V58 T59 F66 Y143 I262	V58-A62 WeakPolarHBondContact O-CB 3.49Å; V58-A62 PolarHBondContact O-N 3.25Å; V58-A62 VanDerWaalsContact O-N 3.16Å; T59-A62 PolarHBondContact O-N 3.23Å; A62-F66 WeakPolarHBondContact O-CB 3.44Å; A62-F66 WeakPolarHBondContact O-CD2 3.17Å; A62-F66 PolarHBondContact O-N 3.29Å; A62-Y143 WeakPolarHBondContact CB-OH 3.5Å; A62-I262 HydrophobicContact CB-CD1 3.89Å
63	L	88.9	Confident	85.5	Confident	7 Å²	7	27.7 Å²	27.7	4%	0.037	15%	0.154	C	C	.	.	H	α-helix	trans	-68.9	-40.9	175.9	-64.7	170.9	0	0	0	111.8	T59 C61 F65 L67 Y143 I146 W147 Y164 F167	T59-L63 WeakPolarHBondContact O-CG 3.45Å; T59-L63 PolarHBondContact O-N 3.43Å; C61-L63 PolarHBondContact O-N 3.17Å; L63-F65 PolarHBondContact O-N 3.47Å; L63-L67 HydrophobicContact CB-CB 4.43Å; L63-L67 HydrophobicContact CD2-CB 4.33Å; L63-L67 HydrophobicContact CD2-CD1 4.23Å; L63-L67 HydrophobicContact CD2-CD2 4.09Å; L63-L67 HydrophobicContact CD2-CG 4.45Å; L63-L67 WeakPolarHBondContact O-CB 3.47Å; L63-L67 PolarHBondContact O-N 3.1Å; L63-L67 VanDerWaalsContact O-N 3.16Å; L63-Y143 HydrophobicContact CD1-CD2 4.28Å; L63-Y143 HydrophobicContact CD1-CE2 4.13Å; L63-Y143 HydrophobicContact CD2-CE2 4.09Å; L63-Y143 HydrophobicContact CG-CE2 3.94Å; L63-I146 HydrophobicContact CD2-CD1 4.4Å; L63-I146 HydrophobicContact CD2-CG2 4.05Å; L63-W147 HydrophobicContact CD2-CZ2 3.79Å; L63-Y164 HydrophobicContact CD1-CE2 4.24Å; L63-F167 HydrophobicContact CD1-CD1 3.57Å; L63-F167 HydrophobicContact CD1-CE1 3.19Å; L63-F167 HydrophobicContact CD1-CZ 4.03Å
64	G	81.3	Confident	84.5	Confident	36 Å²	36	28 Å²	28	37%	0.371	16%	0.155	S	C	.	.	H	α-helix	trans	-59.8	-44.2	-178.4	0	0	0	0	0	113.8	G60 C61	G60-G64 WeakPolarHBondContact O-CA 3.23Å; G60-G64 PolarHBondContact O-N 3.45Å; C61-G64 PolarHBondContact O-N 2.9Å
65	F	75.3	Confident	83.1	Confident	86 Å²	86	27.6 Å²	27.6	38%	0.377	15%	0.152	S	C	.	.	H	α-helix	trans	-89.7	-36.8	-177.9	-68.3	-61.6	0	0	0	113.6	C61 L63 T211 L346	C61-F65 HydrophobicContact CB-CD2 4.41Å; C61-F65 HydrophobicContact CB-CE2 4.4Å; C61-F65 VanDerWaalsContact O-CD2 3.24Å; C61-F65 WeakPolarHBondContact O-CD2 3.18Å; C61-F65 PolarHBondContact O-N 3.48Å; L63-F65 PolarHBondContact O-N 3.47Å; F65-T211 HydrophobicContact CD2-CG2 4.47Å; F65-L346 HydrophobicContact CZ-CD2 4.5Å
66	F	82.5	Confident	81.6	Confident	23 Å²	23	30.7 Å²	30.7	10%	0.101	17%	0.166	C	C	.	.	H	α-helix	trans	-112.5	-16.5	-164.3	-58.5	-89.7	0	0	0	114.7	A62 Q68 I69 Y70 W147 Q214 Y255	A62-F66 WeakPolarHBondContact O-CB 3.44Å; A62-F66 WeakPolarHBondContact O-CD2 3.17Å; A62-F66 PolarHBondContact O-N 3.29Å; F66-Q68 PolarHBondContact O-N 3Å; F66-I69 PolarHBondContact O-N 3.29Å; F66-Y70 WeakPolarHBondContact O-CB 3.3Å; F66-Y70 PolarHBondContact O-N 3.2Å; F66-W147 HydrophobicContact CB-CH2 3.98Å; F66-Q214 HydrophobicContact CB-CG 3.87Å; F66-Q214 HydrophobicContact CD1-CG 3.9Å; F66-Q214 HydrophobicContact CD2-CB 3.63Å; F66-Q214 HydrophobicContact CD2-CG 3.36Å; F66-Q214 HydrophobicContact CE1-CB 4.41Å; F66-Q214 HydrophobicContact CE1-CG 4.26Å; F66-Q214 HydrophobicContact CE2-CB 3.52Å; F66-Q214 HydrophobicContact CE2-CG 3.79Å; F66-Q214 HydrophobicContact CG-CB 4.15Å; F66-Q214 HydrophobicContact CG-CG 3.43Å; F66-Q214 VanDerWaalsContact CG-CG 3.43Å; F66-Q214 HydrophobicContact CZ-CB 3.94Å; F66-Q214 HydrophobicContact CZ-CG 4.21Å; F66-Y255 HydrophobicContact CB-CE1 4.09Å
67	L	85.2	Confident	79.9	Confident	2 Å²	2	32.3 Å²	32.3	1%	0.01	17%	0.174	C	C	.	.	H	α-helix	trans	-64.2	-42.1	-178.2	-177.1	61.2	0	0	0	111.6	L63 I69 Y70 L71 L99 I146 Y164	L63-L67 HydrophobicContact CB-CB 4.43Å; L63-L67 HydrophobicContact CD2-CB 4.33Å; L63-L67 HydrophobicContact CD2-CD1 4.23Å; L63-L67 HydrophobicContact CD2-CD2 4.09Å; L63-L67 HydrophobicContact CD2-CG 4.45Å; L63-L67 WeakPolarHBondContact O-CB 3.47Å; L63-L67 PolarHBondContact O-N 3.1Å; L63-L67 VanDerWaalsContact O-N 3.16Å; L67-I69 PolarHBondContact O-N 2.78Å; L67-Y70 PolarHBondContact O-N 2.99Å; L67-L71 HydrophobicContact CD1-CD1 4.34Å; L67-L71 HydrophobicContact CD1-CG 4.2Å; L67-L71 HydrophobicContact CG-CD1 4.09Å; L67-L71 HydrophobicContact CG-CG 4.38Å; L67-L71 WeakPolarHBondContact O-CB 2.94Å; L67-L71 VanDerWaalsContact O-CG 3.31Å; L67-L71 WeakPolarHBondContact O-CG 3.44Å; L67-L71 PolarHBondContact O-N 2.68Å; L67-L99 HydrophobicContact CB-CD2 4.31Å; L67-L99 HydrophobicContact CD2-CD2 3.54Å; L67-L99 HydrophobicContact CG-CD2 3.86Å; L67-I146 HydrophobicContact CD1-CG2 3.54Å; L67-Y164 HydrophobicContact CD2-CD2 4.12Å; L67-Y164 HydrophobicContact CD2-CE1 4.35Å; L67-Y164 HydrophobicContact CD2-CE2 4Å; L67-Y164 HydrophobicContact CD2-CG 4.44Å
68	Q	81.1	Confident	77.7	Confident	107 Å²	107	36.7 Å²	36.7	50%	0.5	20%	0.199	S	C	.	.	H	α-helix	trans	-61.1	-46.2	177.1	-176.6	176.8	-5.1	0	0	111.5	F66 Y70 L71 L72 L99	F66-Q68 PolarHBondContact O-N 3Å; Q68-Y70 VanDerWaalsContact C-N 3.33Å; Q68-Y70 PolarHBondContact O-N 3.25Å; Q68-L71 PolarHBondContact O-N 2.96Å; Q68-L72 HydrophobicContact CG-CD1 3.95Å; Q68-L72 WeakPolarHBondContact O-CB 3.44Å; Q68-L72 VanDerWaalsContact O-CG 3.29Å; Q68-L72 WeakPolarHBondContact O-CG 3.45Å; Q68-L72 PolarHBondContact O-N 3.21Å; Q68-L72 VanDerWaalsContact O-N 3.13Å; Q68-L99 HydrophobicContact CB-CD1 3.68Å; Q68-L99 HydrophobicContact CG-CD1 3.83Å
69	I	76.9	Confident	75.3	Confident	74 Å²	74	44.1 Å²	44.1	38%	0.379	23%	0.234	S	C	.	.	H	α-helix	trans	-60.4	-46.7	178	-61.5	173.9	0	0	0	109.7	F66 L67 L71 L72 D73	F66-I69 PolarHBondContact O-N 3.29Å; L67-I69 PolarHBondContact O-N 2.78Å; I69-L71 PolarHBondContact O-N 2.99Å; I69-L72 PolarHBondContact O-N 2.68Å; I69-D73 WeakPolarHBondContact O-CB 3.31Å; I69-D73 PolarHBondContact O-N 3.42Å
70	Y	81	Confident	72.7	Confident	0 Å²	0	52.2 Å²	52.2	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-62.6	-44.3	179.2	176	-93.3	0	0	0	113.1	F66 L67 Q68 L72 V74 A75 W147 V149 Y160 Y255	F66-Y70 WeakPolarHBondContact O-CB 3.3Å; F66-Y70 PolarHBondContact O-N 3.2Å; L67-Y70 PolarHBondContact O-N 2.99Å; Q68-Y70 VanDerWaalsContact C-N 3.33Å; Q68-Y70 PolarHBondContact O-N 3.25Å; Y70-L72 VanDerWaalsContact C-N 3.26Å; Y70-L72 PolarHBondContact O-N 3.05Å; Y70-V74 HydrophobicContact CD2-CB 3.71Å; Y70-V74 HydrophobicContact CD2-CG1 3.82Å; Y70-V74 HydrophobicContact CD2-CG2 4.08Å; Y70-V74 HydrophobicContact CE2-CB 3.97Å; Y70-V74 HydrophobicContact CE2-CG1 3.58Å; Y70-V74 HydrophobicContact CG-CB 4.3Å; Y70-V74 WeakPolarHBondContact O-CA 3.36Å; Y70-V74 WeakPolarHBondContact O-CB 3.01Å; Y70-V74 PolarHBondContact O-N 3.03Å; Y70-A75 HydrophobicContact CE1-CB 4.45Å; Y70-A75 PolarHBondContact O-N 3.12Å; Y70-W147 HydrophobicContact CD1-CE3 4.06Å; Y70-W147 HydrophobicContact CD1-CZ3 4.21Å; Y70-W147 AromaticContact CD2-CE3 3.78Å; Y70-W147 HydrophobicContact CD2-CE3 3.78Å; Y70-W147 AromaticContact CD2-CZ3 3.98Å; Y70-W147 HydrophobicContact CD2-CZ3 3.98Å; Y70-W147 HydrophobicContact CE1-CE3 4.37Å; Y70-W147 HydrophobicContact CE2-CE3 4.08Å; Y70-W147 AromaticContact CG-CE3 3.76Å; Y70-W147 HydrophobicContact CG-CE3 3.76Å; Y70-W147 AromaticContact CG-CZ3 3.68Å; Y70-W147 HydrophobicContact CG-CZ3 3.68Å; Y70-W147 PolarHBondContact OH-O 3.15Å; Y70-V149 WeakPolarHBondContact OH-CG2 3.22Å; Y70-Y160 HydrophobicContact CE1-CE1 4.07Å; Y70-Y255 AromaticContact CD2-CD1 3.77Å; Y70-Y255 HydrophobicContact CD2-CD1 3.77Å; Y70-Y255 AromaticContact CD2-CD2 3.69Å; Y70-Y255 HydrophobicContact CD2-CD2 3.69Å; Y70-Y255 HydrophobicContact CD2-CE1 4.03Å; Y70-Y255 AromaticContact CD2-CE2 3.97Å; Y70-Y255 HydrophobicContact CD2-CE2 3.97Å; Y70-Y255 AromaticContact CD2-CG 3.57Å; Y70-Y255 HydrophobicContact CD2-CG 3.57Å; Y70-Y255 HydrophobicContact CE2-CD1 4.44Å; Y70-Y255 HydrophobicContact CE2-CD2 4.2Å; Y70-Y255 AromaticContact CE2-CG 3.96Å; Y70-Y255 HydrophobicContact CE2-CG 3.96Å; Y70-Y255 HydrophobicContact CG-CD1 4.45Å; Y70-Y255 HydrophobicContact CG-CE1 4.43Å
71	L	80.1	Confident	70.4	Confident	1 Å²	1	57.6 Å²	57.6	1%	0.005	30%	0.297	C	S	.	.	H	α-helix	trans	-63.8	-32.6	178.3	-71.4	175.2	0	0	0	112.5	L67 Q68 I69 A75 V90 A95 I98 L99 Y160	L67-L71 HydrophobicContact CD1-CD1 4.34Å; L67-L71 HydrophobicContact CD1-CG 4.2Å; L67-L71 HydrophobicContact CG-CD1 4.09Å; L67-L71 HydrophobicContact CG-CG 4.38Å; L67-L71 WeakPolarHBondContact O-CB 2.94Å; L67-L71 VanDerWaalsContact O-CG 3.31Å; L67-L71 WeakPolarHBondContact O-CG 3.44Å; L67-L71 PolarHBondContact O-N 2.68Å; Q68-L71 PolarHBondContact O-N 2.96Å; I69-L71 PolarHBondContact O-N 2.99Å; L71-A75 HydrophobicContact CD2-CB 4.41Å; L71-V90 HydrophobicContact CB-CG1 4.3Å; L71-V90 HydrophobicContact CD2-CG1 4.33Å; L71-A95 HydrophobicContact CB-CB 3.98Å; L71-A95 HydrophobicContact CD1-CB 4.34Å; L71-I98 HydrophobicContact CD1-CB 4.43Å; L71-I98 HydrophobicContact CD1-CD1 4.49Å; L71-I98 HydrophobicContact CD1-CG2 4.16Å; L71-L99 HydrophobicContact CD1-CD2 4.32Å; L71-L99 HydrophobicContact CD1-CG 4.35Å; L71-Y160 HydrophobicContact CD2-CD1 3.89Å; L71-Y160 HydrophobicContact CD2-CD2 3.88Å; L71-Y160 HydrophobicContact CD2-CE1 4.18Å; L71-Y160 HydrophobicContact CD2-CE2 4.16Å; L71-Y160 HydrophobicContact CD2-CG 3.75Å
72	L	73.8	Confident	68.2	Low	36 Å²	36	62 Å²	62	19%	0.188	32%	0.323	C	S	.	.	H	α-helix	trans	-86.4	-44.5	-178.5	-67.1	174.8	0	0	0	113	Q68 I69 Y70 Q76 P92 A95	Q68-L72 HydrophobicContact CG-CD1 3.95Å; Q68-L72 WeakPolarHBondContact O-CB 3.44Å; Q68-L72 VanDerWaalsContact O-CG 3.29Å; Q68-L72 WeakPolarHBondContact O-CG 3.45Å; Q68-L72 PolarHBondContact O-N 3.21Å; Q68-L72 VanDerWaalsContact O-N 3.13Å; I69-L72 PolarHBondContact O-N 2.68Å; Y70-L72 VanDerWaalsContact C-N 3.26Å; Y70-L72 PolarHBondContact O-N 3.05Å; L72-Q76 VanDerWaalsContact O-CG 3.22Å; L72-Q76 WeakPolarHBondContact O-CG 3.23Å; L72-Q76 PolarHBondContact O-OE1 2.88Å; L72-P92 HydrophobicContact CD2-CB 4.06Å; L72-P92 HydrophobicContact CD2-CG 4.23Å; L72-A95 HydrophobicContact CD2-CB 3.93Å; L72-A95 HydrophobicContact CG-CB 4.46Å
73	D	69.5	Low	65.9	Low	61 Å²	61	69.3 Å²	69.3	33%	0.326	36%	0.355	S	S	.	.	H	α-helix	trans	-100.6	-17.4	-169	-61.8	-26.1	0	0	0	113.2	I69 R471	I69-D73 WeakPolarHBondContact O-CB 3.31Å; I69-D73 PolarHBondContact O-N 3.42Å; D73-R471 IonicContact OD1-NH2 2.81Å; D73-R471 IonicContact OD2-NH2 3.06Å
74	V	71.6	Confident	63.7	Low	6 Å²	6	74.9 Å²	74.9	4%	0.036	39%	0.393	C	S	.	.	T	Hydrogen-bonded Turn	trans	-122	-39.8	-171.5	-175.6	0	0	0	0	113.3	Y70 Q76 Q252 Y255	Y70-V74 HydrophobicContact CD2-CB 3.71Å; Y70-V74 HydrophobicContact CD2-CG1 3.82Å; Y70-V74 HydrophobicContact CD2-CG2 4.08Å; Y70-V74 HydrophobicContact CE2-CB 3.97Å; Y70-V74 HydrophobicContact CE2-CG1 3.58Å; Y70-V74 HydrophobicContact CG-CB 4.3Å; Y70-V74 WeakPolarHBondContact O-CA 3.36Å; Y70-V74 WeakPolarHBondContact O-CB 3.01Å; Y70-V74 PolarHBondContact O-N 3.03Å; V74-Q76 VanDerWaalsContact C-N 3.33Å; V74-Q252 HydrophobicContact CG1-CB 4.3Å; V74-Q252 HydrophobicContact CG1-CG 3.26Å; V74-Q252 PolarHBondContact O-NE2 3.17Å; V74-Y255 HydrophobicContact CG2-CD2 4.29Å; V74-Y255 HydrophobicContact CG2-CE2 3.92Å
75	A	65.9	Low	61.9	Low	0 Å²	0	82.4 Å²	82.4	0%	0	42%	0.416	C	S	.	.	S	Bend	trans	-79	-18.1	178.2	0	0	0	0	0	112.7	Y70 L71 K77 Y160	Y70-A75 HydrophobicContact CE1-CB 4.45Å; Y70-A75 PolarHBondContact O-N 3.12Å; L71-A75 HydrophobicContact CD2-CB 4.41Å; A75-K77 PolarHBondContact O-N 3.48Å; A75-K77 VanDerWaalsContact O-N 3.09Å; A75-Y160 HydrophobicContact CB-CE2 3.97Å
76	Q	64.1	Low	60.3	Low	67 Å²	67	81 Å²	81	31%	0.313	42%	0.417	S	S	.	.			trans	-68.1	105	167.8	-71.7	-167.7	-13.2	0	0	108.9	L72 V74 D78 V90	L72-Q76 VanDerWaalsContact O-CG 3.22Å; L72-Q76 WeakPolarHBondContact O-CG 3.23Å; L72-Q76 PolarHBondContact O-OE1 2.88Å; V74-Q76 VanDerWaalsContact C-N 3.33Å; Q76-D78 PolarHBondContact O-N 3.35Å; Q76-V90 VanDerWaalsContact CG-O 3.24Å; Q76-V90 WeakPolarHBondContact CG-O 3.43Å; Q76-V90 PolarHBondContact NE2-O 3.39Å
77	K	55.7	Low	58.7	Low	80 Å²	80	84.9 Å²	84.9	35%	0.348	45%	0.445	S	S	.	.			trans	-70.7	118.6	161.5	-71.5	-174.5	175.9	178	0	106.7	A75 E79 Q89 D151	A75-K77 PolarHBondContact O-N 3.48Å; A75-K77 VanDerWaalsContact O-N 3.09Å; K77-E79 PolarHBondContact O-N 2.99Å; K77-Q89 PolarHBondContact O-NE2 2.68Å; K77-D151 IonicContact NZ-OD1 3.52Å
78	D	46.4	Very low	57	Low	130 Å²	130	88 Å²	88	70%	0.695	46%	0.458	S	S	*	.			trans	-59.1	83.2	169.8	-70.1	-51.8	0	0	0	109.8	Q76 H248	Q76-D78 PolarHBondContact O-N 3.35Å; D78-H248 IonicContact OD2-CE1 3.01Å; D78-H248 IonicContact OD2-NE2 3.22Å
79	E	42.7	Very low	55.7	Low	159 Å²	159	86 Å²	86	74%	0.743	45%	0.449	S	S	*	.			trans	-108.5	112.1	150.5	-80.6	-173.8	163.4	0	0	105.9	K77	K77-E79 PolarHBondContact O-N 2.99Å
80	E	39	Very low	54.8	Low	171 Å²	171	82.5 Å²	82.5	80%	0.799	43%	0.431	S	S	*	.			trans	-11.1	126.5	177.7	-74.7	176.5	117.8	0	0	117	V82	E80-V82 PolarHBondContact O-N 3.49Å
81	V	42.1	Very low	54.1	Low	147 Å²	147	83.6 Å²	83.6	89%	0.891	44%	0.442	S	S	*	.	T	Hydrogen-bonded Turn	trans	9.1	-5.5	143.4	-175.5	0	0	0	0	121.7
82	V	40.5	Very low	53.7	Low	109 Å²	109	87.6 Å²	87.6	66%	0.661	47%	0.468	S	S	*	.	T	Hydrogen-bonded Turn	trans	-104.6	-8.8	-164.5	-176.2	0	0	0	0	115.1	E80	E80-V82 PolarHBondContact O-N 3.49Å
83	F	41.1	Very low	53.8	Low	154 Å²	154	93.5 Å²	93.5	68%	0.675	49%	0.493	S	S	*	.			trans	-122.3	74.4	177.7	-81.8	-84.4	0	0	0	114.3	F85	F83-F85 PolarHBondContact O-N 3.13Å
84	C	42.8	Very low	54.2	Low	124 Å²	124	91.3 Å²	91.3	84%	0.838	48%	0.482	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.8	9.2	165.8	-71.2	0	0	0	0	114.7
85	F	41.9	Very low	54.5	Low	193 Å²	193	91.1 Å²	91.1	85%	0.846	48%	0.481	S	S	*	.	T	Hydrogen-bonded Turn	trans	-131	10.3	-171.7	-89.3	-82.6	0	0	0	115.4	F83 P87	F83-F85 PolarHBondContact O-N 3.13Å; F85-P87 VanDerWaalsContact O-CD 3.23Å; F85-P87 WeakPolarHBondContact O-CD 3.48Å
86	S	42.9	Very low	55.2	Low	58 Å²	58	94.4 Å²	94.4	41%	0.406	50%	0.504	S	S	.	.			trans	-89	110.4	172.1	-85.7	0	0	0	0	110.6	F88	S86-F88 PolarHBondContact O-N 3.35Å
87	P	49.3	Very low	56.2	Low	104 Å²	104	94.4 Å²	94.4	68%	0.675	51%	0.505	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67	3.1	179.6	27.2	-34.5	0	0	0	114.3	F85	F85-P87 VanDerWaalsContact O-CD 3.23Å; F85-P87 WeakPolarHBondContact O-CD 3.48Å
88	F	48.9	Very low	57.7	Low	68 Å²	68	90.7 Å²	90.7	30%	0.298	49%	0.489	S	S	.	.	T	Hydrogen-bonded Turn	trans	-112.6	-7.6	-168.8	-101.4	-84.8	0	0	0	115.4	S86 H154 Y158	S86-F88 PolarHBondContact O-N 3.35Å; F88-H154 HydrophobicContact CD1-CB 4.25Å; F88-H154 WeakPolarHBondContact CD1-O 3.47Å; F88-H154 VanDerWaalsContact CE1-C 3.45Å; F88-H154 WeakPolarHBondContact CE1-O 3.36Å; F88-Y158 HydrophobicContact CD1-CD2 4.15Å; F88-Y158 HydrophobicContact CD1-CE2 4.08Å; F88-Y158 AromaticContact CE1-CD2 3.46Å; F88-Y158 HydrophobicContact CE1-CD2 3.46Å; F88-Y158 VanDerWaalsContact CE1-CD2 3.46Å; F88-Y158 AromaticContact CE1-CE2 3.34Å; F88-Y158 HydrophobicContact CE1-CE2 3.34Å; F88-Y158 AromaticContact CE2-CE2 3.95Å; F88-Y158 HydrophobicContact CE2-CE2 3.95Å; F88-Y158 AromaticContact CZ-CD2 3.89Å; F88-Y158 HydrophobicContact CZ-CD2 3.89Å; F88-Y158 AromaticContact CZ-CE2 3.29Å; F88-Y158 HydrophobicContact CZ-CE2 3.29Å
89	Q	53.5	Low	59.6	Low	64 Å²	64	86.1 Å²	86.1	30%	0.299	47%	0.465	S	S	.	.	S	Bend	trans	-98.2	149.8	174.4	-159	163.3	5.1	0	0	109.8	K77 G91 S94	K77-Q89 PolarHBondContact O-NE2 2.68Å; Q89-G91 PolarHBondContact O-N 3.46Å; Q89-S94 PolarHBondContact O-OG 2.59Å
90	V	58	Low	61.6	Low	1 Å²	1	86 Å²	86	1%	0.006	46%	0.462	C	S	.	.			trans	-76.8	71.1	-177.4	-167.4	0	0	0	0	110.1	L71 Q76 A95 Q156 Y160	L71-V90 HydrophobicContact CB-CG1 4.3Å; L71-V90 HydrophobicContact CD2-CG1 4.33Å; Q76-V90 VanDerWaalsContact CG-O 3.24Å; Q76-V90 WeakPolarHBondContact CG-O 3.43Å; Q76-V90 PolarHBondContact NE2-O 3.39Å; V90-A95 HydrophobicContact CG1-CB 4.28Å; V90-Q156 HydrophobicContact CG2-CB 3.83Å; V90-Y160 HydrophobicContact CG2-CD2 4.07Å; V90-Y160 HydrophobicContact CG2-CE2 4.06Å
91	G	66.8	Low	64.1	Low	23 Å²	23	80.2 Å²	80.2	24%	0.237	44%	0.438	C	S	.	.			trans	-72.6	169.6	169.5	0	0	0	0	0	111.9	Q89 F93 S94 A95	Q89-G91 PolarHBondContact O-N 3.46Å; G91-F93 PolarHBondContact O-N 3.43Å; G91-F93 VanDerWaalsContact O-N 3.17Å; G91-S94 PolarHBondContact O-N 3.34Å; G91-A95 PolarHBondContact O-N 3.24Å
92	P	72.1	Confident	66.3	Low	84 Å²	84	73.2 Å²	73.2	55%	0.545	40%	0.396	S	S	.	.	H	α-helix	trans	-55.4	-34.5	176.8	-25.8	34.6	0	0	0	113.8	L72 S96	L72-P92 HydrophobicContact CD2-CB 4.06Å; L72-P92 HydrophobicContact CD2-CG 4.23Å; P92-S96 WeakPolarHBondContact O-CB 3.48Å; P92-S96 PolarHBondContact O-N 3.01Å; P92-S96 PolarHBondContact O-OG 3.27Å
93	F	75.6	Confident	68.4	Low	161 Å²	161	73.3 Å²	73.3	71%	0.706	39%	0.385	S	S	*	.	H	α-helix	trans	-65.8	-48.8	174.5	-177.3	-106.5	0	0	0	112.1	G91 A95 S96 I97	G91-F93 PolarHBondContact O-N 3.43Å; G91-F93 VanDerWaalsContact O-N 3.17Å; F93-A95 PolarHBondContact O-N 3.49Å; F93-S96 PolarHBondContact O-N 3.32Å; F93-I97 HydrophobicContact CD1-CD1 3.69Å; F93-I97 HydrophobicContact CE1-CD1 3.26Å; F93-I97 HydrophobicContact CE1-CG1 4.42Å; F93-I97 HydrophobicContact CE2-CD1 4.27Å; F93-I97 HydrophobicContact CG-CD1 4.37Å; F93-I97 HydrophobicContact CZ-CD1 3.59Å; F93-I97 HydrophobicContact CZ-CG1 4.46Å; F93-I97 WeakPolarHBondContact O-CG1 3.32Å; F93-I97 PolarHBondContact O-N 3.07Å
94	S	77.3	Confident	70.6	Confident	14 Å²	14	67.9 Å²	67.9	10%	0.098	37%	0.368	C	S	.	.	H	α-helix	trans	-61.7	-43.3	177.2	-54.3	0	0	0	0	112	Q89 G91 S96 I97 I98	Q89-S94 PolarHBondContact O-OG 2.59Å; G91-S94 PolarHBondContact O-N 3.34Å; S94-S96 VanDerWaalsContact C-N 3.35Å; S94-S96 PolarHBondContact O-N 3.15Å; S94-I97 PolarHBondContact O-N 3.44Å; S94-I98 WeakPolarHBondContact O-CD1 3.47Å; S94-I98 VanDerWaalsContact O-CG1 3.27Å; S94-I98 WeakPolarHBondContact O-CG1 3.45Å; S94-I98 PolarHBondContact O-N 3.34Å
95	A	78.7	Confident	72.9	Confident	2 Å²	2	67.3 Å²	67.3	2%	0.017	35%	0.348	C	S	.	.	H	α-helix	trans	-60.9	-43.2	176.3	0	0	0	0	0	111.8	L71 L72 V90 G91 F93 I97 I98 L99	L71-A95 HydrophobicContact CB-CB 3.98Å; L71-A95 HydrophobicContact CD1-CB 4.34Å; L72-A95 HydrophobicContact CD2-CB 3.93Å; L72-A95 HydrophobicContact CG-CB 4.46Å; V90-A95 HydrophobicContact CG1-CB 4.28Å; G91-A95 PolarHBondContact O-N 3.24Å; F93-A95 PolarHBondContact O-N 3.49Å; A95-I97 VanDerWaalsContact C-N 3.35Å; A95-I97 PolarHBondContact O-N 2.9Å; A95-I98 PolarHBondContact O-N 3.48Å; A95-L99 WeakPolarHBondContact O-CG 3.37Å; A95-L99 PolarHBondContact O-N 3Å; A95-L99 VanDerWaalsContact O-N 3.07Å
96	S	79.9	Confident	75.2	Confident	70 Å²	70	58.6 Å²	58.6	49%	0.49	31%	0.311	S	S	.	.	H	α-helix	trans	-62.9	-40.6	176.1	-57.2	0	0	0	0	111.9	P92 F93 S94 F100	P92-S96 WeakPolarHBondContact O-CB 3.48Å; P92-S96 PolarHBondContact O-N 3.01Å; P92-S96 PolarHBondContact O-OG 3.27Å; F93-S96 PolarHBondContact O-N 3.32Å; S94-S96 VanDerWaalsContact C-N 3.35Å; S94-S96 PolarHBondContact O-N 3.15Å; S96-F100 VanDerWaalsContact O-CB 3.28Å; S96-F100 WeakPolarHBondContact O-CB 3.45Å; S96-F100 PolarHBondContact O-N 2.98Å
97	I	84.9	Confident	77.3	Confident	66 Å²	66	56.6 Å²	56.6	34%	0.338	30%	0.297	S	S	.	.	H	α-helix	trans	-62.7	-46.7	174.6	-70.9	169.8	0	0	0	111.1	F93 S94 A95 L99 F100 V101	F93-I97 HydrophobicContact CD1-CD1 3.69Å; F93-I97 HydrophobicContact CE1-CD1 3.26Å; F93-I97 HydrophobicContact CE1-CG1 4.42Å; F93-I97 HydrophobicContact CE2-CD1 4.27Å; F93-I97 HydrophobicContact CG-CD1 4.37Å; F93-I97 HydrophobicContact CZ-CD1 3.59Å; F93-I97 HydrophobicContact CZ-CG1 4.46Å; F93-I97 WeakPolarHBondContact O-CG1 3.32Å; F93-I97 PolarHBondContact O-N 3.07Å; S94-I97 PolarHBondContact O-N 3.44Å; A95-I97 VanDerWaalsContact C-N 3.35Å; A95-I97 PolarHBondContact O-N 2.9Å; I97-L99 VanDerWaalsContact C-N 3.33Å; I97-L99 PolarHBondContact O-N 3.02Å; I97-F100 PolarHBondContact O-N 2.95Å; I97-V101 HydrophobicContact CG2-CG2 3.94Å; I97-V101 VanDerWaalsContact O-CB 3.3Å; I97-V101 WeakPolarHBondContact O-CB 3.39Å; I97-V101 VanDerWaalsContact O-CG2 3.24Å; I97-V101 WeakPolarHBondContact O-CG2 3.31Å; I97-V101 PolarHBondContact O-N 2.85Å
98	I	87.3	Confident	79.2	Confident	2 Å²	2	56 Å²	56	1%	0.01	29%	0.288	C	S	.	.	H	α-helix	trans	-57.2	-49	179.9	-68.8	158.8	0	0	0	110.2	L71 S94 A95 G102 T157 L161 Y164	L71-I98 HydrophobicContact CD1-CB 4.43Å; L71-I98 HydrophobicContact CD1-CD1 4.49Å; L71-I98 HydrophobicContact CD1-CG2 4.16Å; S94-I98 WeakPolarHBondContact O-CD1 3.47Å; S94-I98 VanDerWaalsContact O-CG1 3.27Å; S94-I98 WeakPolarHBondContact O-CG1 3.45Å; S94-I98 PolarHBondContact O-N 3.34Å; A95-I98 PolarHBondContact O-N 3.48Å; I98-G102 PolarHBondContact O-N 3.31Å; I98-T157 HydrophobicContact CD1-CG2 4.12Å; I98-T157 HydrophobicContact CG1-CG2 4.26Å; I98-L161 HydrophobicContact CG1-CB 4.46Å; I98-Y164 HydrophobicContact CG2-CD1 4.06Å
99	L	85.8	Confident	81.2	Confident	34 Å²	34	53 Å²	53	18%	0.178	28%	0.275	C	S	.	.	H	α-helix	trans	-65.2	-44.9	-179.4	-65.5	172.9	0	0	0	111.9	L67 Q68 L71 A95 I97 R103	L67-L99 HydrophobicContact CB-CD2 4.31Å; L67-L99 HydrophobicContact CD2-CD2 3.54Å; L67-L99 HydrophobicContact CG-CD2 3.86Å; Q68-L99 HydrophobicContact CB-CD1 3.68Å; Q68-L99 HydrophobicContact CG-CD1 3.83Å; L71-L99 HydrophobicContact CD1-CD2 4.32Å; L71-L99 HydrophobicContact CD1-CG 4.35Å; A95-L99 WeakPolarHBondContact O-CG 3.37Å; A95-L99 PolarHBondContact O-N 3Å; A95-L99 VanDerWaalsContact O-N 3.07Å; I97-L99 VanDerWaalsContact C-N 3.33Å; I97-L99 PolarHBondContact O-N 3.02Å; L99-R103 WeakPolarHBondContact O-CB 3.44Å; L99-R103 VanDerWaalsContact O-CG 3.28Å; L99-R103 WeakPolarHBondContact O-CG 3.29Å; L99-R103 PolarHBondContact O-N 2.85Å
100	F	86.1	Confident	83	Confident	156 Å²	156	50 Å²	50	68%	0.684	26%	0.261	S	S	*	.	H	α-helix	trans	-64.1	-48.4	179.1	-179.9	-95.6	0	0	0	112	S96 I97 R103 A104	S96-F100 VanDerWaalsContact O-CB 3.28Å; S96-F100 WeakPolarHBondContact O-CB 3.45Å; S96-F100 PolarHBondContact O-N 2.98Å; I97-F100 PolarHBondContact O-N 2.95Å; F100-R103 PolarHBondContact O-N 3.13Å; F100-A104 WeakPolarHBondContact O-CB 3.2Å; F100-A104 PolarHBondContact O-N 2.87Å
101	V	89.6	Confident	84.5	Confident	51 Å²	51	50.7 Å²	50.7	31%	0.309	27%	0.266	S	S	.	.	H	α-helix	trans	-63.4	-43.8	180	171.8	0	0	0	0	110.5	I97 R103 A104 W105 L161	I97-V101 HydrophobicContact CG2-CG2 3.94Å; I97-V101 VanDerWaalsContact O-CB 3.3Å; I97-V101 WeakPolarHBondContact O-CB 3.39Å; I97-V101 VanDerWaalsContact O-CG2 3.24Å; I97-V101 WeakPolarHBondContact O-CG2 3.31Å; I97-V101 PolarHBondContact O-N 2.85Å; V101-R103 PolarHBondContact O-N 2.83Å; V101-A104 PolarHBondContact O-N 2.91Å; V101-W105 VanDerWaalsContact O-CB 3.24Å; V101-W105 WeakPolarHBondContact O-CB 3.38Å; V101-W105 PolarHBondContact O-N 2.99Å; V101-L161 HydrophobicContact CB-CD1 4.37Å; V101-L161 HydrophobicContact CG1-CD1 4.15Å; V101-L161 HydrophobicContact CG1-CG 4.47Å
102	G	88.3	Confident	85.6	Confident	0 Å²	0	53.7 Å²	53.7	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-65.9	-38.3	178.7	0	0	0	0	0	113.1	I98 W105 D106 Y164	I98-G102 PolarHBondContact O-N 3.31Å; G102-W105 WeakPolarHBondContact O-CB 3.38Å; G102-W105 PolarHBondContact O-N 3.22Å; G102-D106 WeakPolarHBondContact O-CB 3.42Å; G102-D106 PolarHBondContact O-N 3.47Å; G102-Y164 VanDerWaalsContact CA-CE1 3.44Å
103	R	84.7	Confident	86.5	Confident	111 Å²	111	50.1 Å²	50.1	42%	0.419	25%	0.252	S	S	.	.	H	α-helix	trans	-66.9	-39.4	173.3	-69.2	-64.4	-178.7	93.9	2.4	113.1	L99 F100 V101 W105 A107	L99-R103 WeakPolarHBondContact O-CB 3.44Å; L99-R103 VanDerWaalsContact O-CG 3.28Å; L99-R103 WeakPolarHBondContact O-CG 3.29Å; L99-R103 PolarHBondContact O-N 2.85Å; F100-R103 PolarHBondContact O-N 3.13Å; V101-R103 PolarHBondContact O-N 2.83Å; R103-W105 VanDerWaalsContact C-N 3.33Å; R103-A107 PolarHBondContact O-N 3.35Å; R103-A107 VanDerWaalsContact O-N 3.16Å
104	A	87.8	Confident	87.1	Confident	40 Å²	40	42.5 Å²	42.5	33%	0.331	22%	0.219	S	C	.	.	H	α-helix	trans	-64.9	-40.6	174.2	0	0	0	0	0	111.1	F100 V101 A107 I108	F100-A104 WeakPolarHBondContact O-CB 3.2Å; F100-A104 PolarHBondContact O-N 2.87Å; V101-A104 PolarHBondContact O-N 2.91Å; A104-A107 PolarHBondContact O-N 3.32Å; A104-I108 WeakPolarHBondContact O-CD1 3.43Å; A104-I108 VanDerWaalsContact O-CG1 3.3Å; A104-I108 WeakPolarHBondContact O-CG1 3.45Å; A104-I108 PolarHBondContact O-N 3.1Å
105	W	91.9	Very high	87.6	Confident	111 Å²	111	43.9 Å²	43.9	42%	0.42	22%	0.223	S	C	.	.	H	α-helix	trans	-62.2	-47.7	176.1	-172.6	-98.2	0	0	0	111.5	V101 G102 R103 A107 I108 T109 C165 T169	V101-W105 VanDerWaalsContact O-CB 3.24Å; V101-W105 WeakPolarHBondContact O-CB 3.38Å; V101-W105 PolarHBondContact O-N 2.99Å; G102-W105 WeakPolarHBondContact O-CB 3.38Å; G102-W105 PolarHBondContact O-N 3.22Å; R103-W105 VanDerWaalsContact C-N 3.33Å; W105-A107 VanDerWaalsContact C-N 3.29Å; W105-A107 PolarHBondContact O-N 3.01Å; W105-I108 PolarHBondContact O-N 3.31Å; W105-T109 HydrophobicContact CD2-CG2 4.45Å; W105-T109 HydrophobicContact CG-CG2 4.4Å; W105-T109 HydrophobicContact CZ2-CG2 4.4Å; W105-T109 WeakPolarHBondContact O-CG2 2.99Å; W105-T109 PolarHBondContact O-N 3.46Å; W105-T109 PolarHBondContact O-OG1 3.44Å; W105-C165 HydrophobicContact CD2-CB 4.47Å; W105-C165 HydrophobicContact CG-CB 4.09Å; W105-C165 PolarHBondContact NE1-O 3.39Å; W105-T169 PolarHBondContact NE1-OG1 2.81Å
106	D	89.9	Confident	88	Confident	11 Å²	11	46.5 Å²	46.5	6%	0.059	24%	0.241	C	C	.	.	H	α-helix	trans	-58	-39	178	-174.5	35.7	0	0	0	112.7	G102 T109 E168 T172 K449	G102-D106 WeakPolarHBondContact O-CB 3.42Å; G102-D106 PolarHBondContact O-N 3.47Å; D106-T109 WeakPolarHBondContact CA-OG1 3.49Å; D106-T109 PolarHBondContact O-OG1 3.06Å; D106-E168 HydrophobicContact CB-CB 3.98Å; D106-E168 HydrophobicContact CB-CG 4.07Å; D106-T172 PolarHBondContact OD1-OG1 3.35Å; D106-K449 PolarHBondContact O-NZ 3.35Å; D106-K449 IonicContact OD1-NZ 2.83Å; D106-K449 PolarHBondContact OD1-NZ 3.19Å; D106-K449 WeakPolarHBondContact OD2-CD 3.44Å; D106-K449 WeakPolarHBondContact OD2-CE 3.25Å; D106-K449 IonicContact OD2-NZ 3.93Å; D106-K449 PolarHBondContact OD2-NZ 2.81Å
107	A	86.8	Confident	88.4	Confident	15 Å²	15	43.2 Å²	43.2	12%	0.124	22%	0.218	C	C	.	.	H	α-helix	trans	-66.9	-37	173.5	0	0	0	0	0	112.5	R103 A104 W105 P111 F446	R103-A107 PolarHBondContact O-N 3.35Å; R103-A107 VanDerWaalsContact O-N 3.16Å; A104-A107 PolarHBondContact O-N 3.32Å; W105-A107 VanDerWaalsContact C-N 3.29Å; W105-A107 PolarHBondContact O-N 3.01Å; A107-P111 VanDerWaalsContact O-CD 3.28Å; A107-P111 WeakPolarHBondContact O-CD 3.38Å; A107-F446 HydrophobicContact CB-CD2 4.17Å; A107-F446 HydrophobicContact CB-CE2 4.27Å; A107-F446 WeakPolarHBondContact O-CD2 3.48Å
108	I	88.5	Confident	88.2	Confident	92 Å²	92	41.4 Å²	41.4	47%	0.472	21%	0.211	S	C	.	.	H	α-helix	trans	-74.9	-35.4	-179.2	-67.2	165.1	0	0	0	111.4	A104 W105 D110 P111 L112	A104-I108 WeakPolarHBondContact O-CD1 3.43Å; A104-I108 VanDerWaalsContact O-CG1 3.3Å; A104-I108 WeakPolarHBondContact O-CG1 3.45Å; A104-I108 PolarHBondContact O-N 3.1Å; W105-I108 PolarHBondContact O-N 3.31Å; I108-D110 PolarHBondContact O-N 3.13Å; I108-P111 VanDerWaalsContact O-CD 3.31Å; I108-P111 WeakPolarHBondContact O-CD 3.48Å; I108-P111 WeakPolarHBondContact O-CG 3.48Å; I108-L112 HydrophobicContact CG2-CD1 3.89Å; I108-L112 WeakPolarHBondContact O-CG 3.28Å
109	T	92.1	Very high	87.9	Confident	6 Å²	6	49.2 Å²	49.2	4%	0.037	25%	0.245	C	C	.	.	H	α-helix	trans	-68	-33.3	-177.6	45.4	0	0	0	0	112.7	W105 D106 L112 V113 T169 T172	W105-T109 HydrophobicContact CD2-CG2 4.45Å; W105-T109 HydrophobicContact CG-CG2 4.4Å; W105-T109 HydrophobicContact CZ2-CG2 4.4Å; W105-T109 WeakPolarHBondContact O-CG2 2.99Å; W105-T109 PolarHBondContact O-N 3.46Å; W105-T109 PolarHBondContact O-OG1 3.44Å; D106-T109 WeakPolarHBondContact CA-OG1 3.49Å; D106-T109 PolarHBondContact O-OG1 3.06Å; T109-L112 PolarHBondContact O-N 2.97Å; T109-V113 WeakPolarHBondContact O-CB 3.37Å; T109-V113 WeakPolarHBondContact O-CG2 3.35Å; T109-V113 PolarHBondContact O-N 2.99Å; T109-T169 HydrophobicContact CG2-CG2 4.27Å; T109-T172 PolarHBondContact OG1-OG1 3.23Å; T109-T172 VanDerWaalsContact OG1-OG1 3.08Å
110	D	90.4	Very high	87.8	Confident	0 Å²	0	49.2 Å²	49.2	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-51.2	-61.5	-179	-73.6	-34.8	0	0	0	113.3	I108 L112 V113 G114 T172 S442 V445 F446 K449	I108-D110 PolarHBondContact O-N 3.13Å; D110-L112 VanDerWaalsContact C-N 3.31Å; D110-L112 PolarHBondContact O-N 3.08Å; D110-V113 PolarHBondContact O-N 3.01Å; D110-G114 PolarHBondContact O-N 3.38Å; D110-T172 WeakPolarHBondContact OD1-CG2 3.46Å; D110-S442 WeakPolarHBondContact O-CB 3.3Å; D110-V445 WeakPolarHBondContact OD2-CG1 3.34Å; D110-F446 HydrophobicContact CB-CB 4.42Å; D110-K449 IonicContact OD1-NZ 3.13Å; D110-K449 PolarHBondContact OD1-NZ 2.86Å; D110-K449 WeakPolarHBondContact OD2-CD 3.45Å; D110-K449 WeakPolarHBondContact OD2-CE 3.47Å; D110-K449 IonicContact OD2-NZ 3.99Å; D110-K449 PolarHBondContact OD2-NZ 3.46Å
111	P	89.1	Confident	87.5	Confident	16 Å²	16	46 Å²	46	10%	0.104	24%	0.244	C	C	.	.	H	α-helix	trans	-67.3	-31.5	-177.1	29.6	-38.3	0	0	0	112.7	A107 I108 F115 Y294	A107-P111 VanDerWaalsContact O-CD 3.28Å; A107-P111 WeakPolarHBondContact O-CD 3.38Å; I108-P111 VanDerWaalsContact O-CD 3.31Å; I108-P111 WeakPolarHBondContact O-CD 3.48Å; I108-P111 WeakPolarHBondContact O-CG 3.48Å; P111-F115 PolarHBondContact O-N 2.71Å; P111-F115 VanDerWaalsContact O-N 3.09Å; P111-Y294 WeakPolarHBondContact CB-OH 3.46Å
112	L	90.9	Very high	87.2	Confident	85 Å²	85	46.5 Å²	46.5	45%	0.445	24%	0.241	S	C	.	.	H	α-helix	trans	-63.8	-47.6	176.2	-69.1	174.8	0	0	0	111.5	I108 T109 D110 F115 C116	I108-L112 HydrophobicContact CG2-CD1 3.89Å; I108-L112 WeakPolarHBondContact O-CG 3.28Å; T109-L112 PolarHBondContact O-N 2.97Å; D110-L112 VanDerWaalsContact C-N 3.31Å; D110-L112 PolarHBondContact O-N 3.08Å; L112-F115 PolarHBondContact O-N 3.18Å; L112-C116 PolarHBondContact O-N 3.44Å; L112-C116 PolarHBondContact O-SG 3.49Å
113	V	91.8	Very high	87	Confident	10 Å²	10	49.5 Å²	49.5	6%	0.061	26%	0.259	C	S	.	.	H	α-helix	trans	-65.8	-42.9	178.3	168.8	0	0	0	0	110.8	T109 D110 F115 C116 I117 T172 V176	T109-V113 WeakPolarHBondContact O-CB 3.37Å; T109-V113 WeakPolarHBondContact O-CG2 3.35Å; T109-V113 PolarHBondContact O-N 2.99Å; D110-V113 PolarHBondContact O-N 3.01Å; V113-F115 PolarHBondContact O-N 3.44Å; V113-C116 PolarHBondContact O-N 2.97Å; V113-C116 VanDerWaalsContact O-N 3.11Å; V113-I117 HydrophobicContact CG1-CD1 3.63Å; V113-I117 HydrophobicContact CG1-CG1 4.3Å; V113-I117 WeakPolarHBondContact O-CD1 3.49Å; V113-I117 VanDerWaalsContact O-CG1 3.27Å; V113-I117 WeakPolarHBondContact O-CG1 3.47Å; V113-I117 PolarHBondContact O-N 3.25Å; V113-T172 HydrophobicContact CB-CG2 3.82Å; V113-T172 HydrophobicContact CG1-CG2 4.23Å; V113-T172 HydrophobicContact CG2-CG2 3.71Å; V113-V176 HydrophobicContact CG1-CB 4.15Å; V113-V176 HydrophobicContact CG1-CG1 4.42Å
114	G	87.8	Confident	86.9	Confident	0 Å²	0	50.9 Å²	50.9	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-55.7	-39.2	175	0	0	0	0	0	112.6	D110 S118	D110-G114 PolarHBondContact O-N 3.38Å; G114-S118 PolarHBondContact O-N 3.26Å; G114-S118 VanDerWaalsContact O-N 3.11Å
115	F	86.6	Confident	86.6	Confident	43 Å²	43	54.1 Å²	54.1	19%	0.189	30%	0.296	C	S	.	.	H	α-helix	trans	-69.4	-45	173.6	177.7	-111.2	0	0	0	113.5	P111 L112 V113 I117 S118 K119 Y294	P111-F115 PolarHBondContact O-N 2.71Å; P111-F115 VanDerWaalsContact O-N 3.09Å; L112-F115 PolarHBondContact O-N 3.18Å; V113-F115 PolarHBondContact O-N 3.44Å; F115-I117 PolarHBondContact O-N 2.95Å; F115-S118 WeakPolarHBondContact O-CB 3.32Å; F115-S118 PolarHBondContact O-N 2.94Å; F115-S118 PolarHBondContact O-OG 3.33Å; F115-K119 PolarHBondContact O-N 3.21Å; F115-Y294 HydrophobicContact CB-CD2 3.32Å; F115-Y294 HydrophobicContact CB-CE2 3.57Å; F115-Y294 HydrophobicContact CB-CG 4.37Å; F115-Y294 AromaticContact CD1-CD2 3.84Å; F115-Y294 HydrophobicContact CD1-CD2 3.84Å; F115-Y294 HydrophobicContact CD1-CG 4.1Å; F115-Y294 AromaticContact CD2-CD2 3.47Å; F115-Y294 HydrophobicContact CD2-CD2 3.47Å; F115-Y294 VanDerWaalsContact CD2-CD2 3.47Å; F115-Y294 HydrophobicContact CD2-CG 4.07Å; F115-Y294 HydrophobicContact CE1-CG 4.44Å; F115-Y294 HydrophobicContact CE2-CD2 4.23Å; F115-Y294 HydrophobicContact CE2-CG 4.41Å; F115-Y294 VanDerWaalsContact CE2-N 3.28Å; F115-Y294 AromaticContact CG-CD2 3.22Å; F115-Y294 HydrophobicContact CG-CD2 3.22Å; F115-Y294 HydrophobicContact CG-CE2 4.02Å; F115-Y294 AromaticContact CG-CG 3.89Å; F115-Y294 HydrophobicContact CG-CG 3.89Å
116	C	88.9	Confident	86.2	Confident	58 Å²	58	49.1 Å²	49.1	39%	0.392	28%	0.279	S	S	.	.	H	α-helix	trans	-57.5	-37.7	177.5	-70.3	0	0	0	0	111.9	L112 V113 K119 S120 W131	L112-C116 PolarHBondContact O-N 3.44Å; L112-C116 PolarHBondContact O-SG 3.49Å; V113-C116 PolarHBondContact O-N 2.97Å; V113-C116 VanDerWaalsContact O-N 3.11Å; C116-K119 PolarHBondContact O-N 3.49Å; C116-S120 PolarHBondContact O-N 3.04Å; C116-W131 HydrophobicContact CB-CH2 3.55Å; C116-W131 HydrophobicContact CB-CZ2 4.02Å; C116-W131 HydrophobicContact CB-CZ3 4.3Å
117	I	87	Confident	86	Confident	0 Å²	0	49.3 Å²	49.3	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-68.4	-41.2	175.4	-65.4	162	0	0	0	111.2	V113 F115 K119 S120 L128 W131 V176 P177 P438	V113-I117 HydrophobicContact CG1-CD1 3.63Å; V113-I117 HydrophobicContact CG1-CG1 4.3Å; V113-I117 WeakPolarHBondContact O-CD1 3.49Å; V113-I117 VanDerWaalsContact O-CG1 3.27Å; V113-I117 WeakPolarHBondContact O-CG1 3.47Å; V113-I117 PolarHBondContact O-N 3.25Å; F115-I117 PolarHBondContact O-N 2.95Å; I117-K119 PolarHBondContact O-N 3.32Å; I117-S120 VanDerWaalsContact O-CB 3.23Å; I117-S120 WeakPolarHBondContact O-CB 3.37Å; I117-S120 PolarHBondContact O-N 2.89Å; I117-L128 HydrophobicContact CG2-CD2 3.28Å; I117-W131 HydrophobicContact CG1-CD2 3.91Å; I117-W131 HydrophobicContact CG1-CE3 4.4Å; I117-W131 HydrophobicContact CG1-CG 4.1Å; I117-W131 HydrophobicContact CG1-CZ2 4.46Å; I117-V176 HydrophobicContact CD1-CB 4.41Å; I117-V176 HydrophobicContact CD1-CG1 3.98Å; I117-P177 HydrophobicContact CD1-CB 3.79Å; I117-P177 HydrophobicContact CD1-CG 3.64Å; I117-P438 HydrophobicContact CB-CB 4.15Å; I117-P438 HydrophobicContact CB-CG 4.38Å; I117-P438 HydrophobicContact CG2-CB 3.93Å; I117-P438 HydrophobicContact CG2-CG 3.69Å
118	S	81.9	Confident	86.2	Confident	29 Å²	29	48.6 Å²	48.6	20%	0.203	27%	0.273	C	S	.	.	H	α-helix	trans	-60	-30.6	177.9	73.1	0	0	0	0	113	G114 F115 G435	G114-S118 PolarHBondContact O-N 3.26Å; G114-S118 VanDerWaalsContact O-N 3.11Å; F115-S118 WeakPolarHBondContact O-CB 3.32Å; F115-S118 PolarHBondContact O-N 2.94Å; F115-S118 PolarHBondContact O-OG 3.33Å; S118-G435 WeakPolarHBondContact CB-O 3.48Å
119	K	80.3	Confident	86.4	Confident	166 Å²	166	44.4 Å²	44.4	72%	0.722	25%	0.251	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.6	-13.3	176	-167.6	176	177.4	-177.7	0	113.3	F115 C116 I117	F115-K119 PolarHBondContact O-N 3.21Å; C116-K119 PolarHBondContact O-N 3.49Å; I117-K119 PolarHBondContact O-N 3.32Å
120	S	83.2	Confident	86.4	Confident	33 Å²	33	44.8 Å²	44.8	23%	0.231	25%	0.254	C	S	.	.	P	Polyproline II helix	trans	-69.6	135.9	-175.1	-160.9	0	0	0	0	111.1	C116 I117 R127 W131	C116-S120 PolarHBondContact O-N 3.04Å; I117-S120 VanDerWaalsContact O-CB 3.23Å; I117-S120 WeakPolarHBondContact O-CB 3.37Å; I117-S120 PolarHBondContact O-N 2.89Å; S120-R127 WeakPolarHBondContact O-CD 3.46Å; S120-W131 PolarHBondContact OG-NE1 2.88Å; S120-W131 VanDerWaalsContact OG-NE1 3.15Å
121	S	80.3	Confident	86.6	Confident	88 Å²	88	48.2 Å²	48.2	62%	0.615	27%	0.267	S	S	*	.	P	Polyproline II helix	trans	-77.3	155.7	177.3	54.5	0	0	0	0	111.6	T123	S121-T123 PolarHBondContact O-N 3.17Å
122	W	82.4	Confident	86.8	Confident	62 Å²	62	47.4 Å²	47.4	24%	0.235	26%	0.262	C	S	.	.	P	Polyproline II helix	trans	-67.9	123.7	171.9	-77.7	83.4	0	0	0	110.2	R127 F184 E279 R281	W122-R127 HydrophobicContact CD2-CB 4.04Å; W122-R127 HydrophobicContact CE3-CB 4.31Å; W122-R127 HydrophobicContact CG-CB 4.39Å; W122-R127 HydrophobicContact CZ2-CB 4.46Å; W122-F184 HydrophobicContact CH2-CD1 4.02Å; W122-F184 HydrophobicContact CH2-CE1 4.43Å; W122-F184 HydrophobicContact CZ2-CD1 4.19Å; W122-F184 HydrophobicContact CZ2-CE1 4.14Å; W122-E279 HydrophobicContact CZ3-CB 4.33Å; W122-R281 HydrophobicContact CD2-CB 4.47Å; W122-R281 HydrophobicContact CD2-CG 4.06Å; W122-R281 HydrophobicContact CE3-CB 4.08Å; W122-R281 HydrophobicContact CE3-CG 4.18Å; W122-R281 VanDerWaalsContact CH2-CA 3.44Å; W122-R281 HydrophobicContact CH2-CB 3.48Å; W122-R281 VanDerWaalsContact CH2-CB 3.48Å; W122-R281 HydrophobicContact CH2-CG 3.77Å; W122-R281 HydrophobicContact CZ2-CB 3.9Å; W122-R281 HydrophobicContact CZ2-CG 3.6Å; W122-R281 HydrophobicContact CZ3-CB 3.58Å; W122-R281 HydrophobicContact CZ3-CG 4.05Å
123	T	84.9	Confident	87	Confident	63 Å²	63	46.4 Å²	46.4	39%	0.387	26%	0.256	S	S	.	.	B	Isolated β-bridge	trans	-105.3	175.8	173.2	74	0	0	0	0	110.9	S121 L125 G126 P130	S121-T123 PolarHBondContact O-N 3.17Å; T123-L125 PolarHBondContact O-N 3.49Å; T123-L125 PolarHBondContact OG1-N 2.93Å; T123-G126 PolarHBondContact N-O 3.37Å; T123-G126 PolarHBondContact O-N 2.88Å; T123-G126 PolarHBondContact OG1-O 3.35Å; T123-P130 HydrophobicContact CG2-CG 4.22Å; T123-P130 VanDerWaalsContact OG1-CG 3.23Å; T123-P130 WeakPolarHBondContact OG1-CG 3.31Å
124	C	82.1	Confident	87.1	Confident	141 Å²	141	53.7 Å²	53.7	95%	0.953	29%	0.287	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59	-26.9	174.5	-59.8	0	0	0	0	113.5
125	L	81.3	Confident	87.5	Confident	108 Å²	108	53.9 Å²	53.9	57%	0.565	29%	0.289	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.5	-8.3	178.2	-63	172.3	0	0	0	112.5	T123 M129 P130 I133	T123-L125 PolarHBondContact O-N 3.49Å; T123-L125 PolarHBondContact OG1-N 2.93Å; L125-M129 HydrophobicContact CB-CB 4.47Å; L125-M129 WeakPolarHBondContact O-CB 3.33Å; L125-P130 HydrophobicContact CB-CG 4.25Å; L125-I133 HydrophobicContact CD1-CD1 4.06Å
126	G	83.9	Confident	87.9	Confident	6 Å²	6	52.5 Å²	52.5	6%	0.062	28%	0.284	C	S	.	.	B	Isolated β-bridge	trans	112.6	-172	-170.7	0	0	0	0	0	112.5	T123	T123-G126 PolarHBondContact N-O 3.37Å; T123-G126 PolarHBondContact O-N 2.88Å; T123-G126 PolarHBondContact OG1-O 3.35Å
127	R	86.5	Confident	88.3	Confident	14 Å²	14	53.4 Å²	53.4	5%	0.053	29%	0.289	C	S	.	.	S	Bend	trans	-94.1	-33.5	176.2	-173.8	172.2	68.6	169.5	6.8	111.7	S120 W122 E279 E437	S120-R127 WeakPolarHBondContact O-CD 3.46Å; W122-R127 HydrophobicContact CD2-CB 4.04Å; W122-R127 HydrophobicContact CE3-CB 4.31Å; W122-R127 HydrophobicContact CG-CB 4.39Å; W122-R127 HydrophobicContact CZ2-CB 4.46Å; R127-E279 PolarHBondContact N-OE1 3.01Å; R127-E279 PolarHBondContact N-OE2 3.07Å; R127-E437 IonicContact CZ-OE2 3.97Å; R127-E437 IonicContact NH2-OE2 3.53Å; R127-E437 PolarHBondContact NH2-OE2 3.46Å
128	L	91	Very high	88.7	Confident	0 Å²	0	56.8 Å²	56.8	0%	0	31%	0.306	C	S	.	.	S	Bend	trans	-98.3	-38	-172.9	-57	177.9	0	0	0	112.9	I117 P130 W131 I132 P177 A180 L181 F184 E279	I117-L128 HydrophobicContact CG2-CD2 3.28Å; L128-P130 VanDerWaalsContact C-CD 3.49Å; L128-W131 WeakPolarHBondContact O-CB 3.42Å; L128-W131 PolarHBondContact O-N 3.39Å; L128-I132 PolarHBondContact O-N 3.03Å; L128-P177 HydrophobicContact CB-CB 3.96Å; L128-P177 HydrophobicContact CD2-CB 4.01Å; L128-A180 HydrophobicContact CD1-CB 4.17Å; L128-L181 HydrophobicContact CD1-CB 4.14Å; L128-L181 HydrophobicContact CD1-CD1 4.05Å; L128-F184 HydrophobicContact CD1-CB 4.48Å; L128-F184 HydrophobicContact CD1-CD2 3.39Å; L128-F184 HydrophobicContact CD1-CE2 3.96Å; L128-F184 HydrophobicContact CD1-CG 4.04Å; L128-F184 HydrophobicContact CG-CD2 4.44Å; L128-E279 WeakPolarHBondContact CA-OE1 3.3Å; L128-E279 WeakPolarHBondContact CB-OE1 3.31Å; L128-E279 PolarHBondContact N-OE1 2.84Å; L128-E279 PolarHBondContact N-OE2 2.89Å; L128-E279 VanDerWaalsContact N-OE2 3.15Å
129	M	91.9	Very high	89.3	Confident	5 Å²	5	55.4 Å²	55.4	3%	0.025	30%	0.297	C	S	.	.	H	α-helix	trans	-58.7	-39.6	-177.1	-72.6	-63.2	177.4	0	0	114.3	L125 W131 I132 I133 L181 T274 V277 E279	L125-M129 HydrophobicContact CB-CB 4.47Å; L125-M129 WeakPolarHBondContact O-CB 3.33Å; M129-W131 VanDerWaalsContact C-N 3.28Å; M129-W131 PolarHBondContact O-N 3.48Å; M129-I132 PolarHBondContact O-N 3.29Å; M129-I132 HydrophobicContact SD-CD1 4.34Å; M129-I133 WeakPolarHBondContact O-CG1 3.49Å; M129-I133 PolarHBondContact O-N 3.15Å; M129-L181 HydrophobicContact CE-CD1 4.09Å; M129-L181 HydrophobicContact CE-CD2 3.63Å; M129-T274 HydrophobicContact SD-CG2 4.31Å; M129-V277 HydrophobicContact CE-CB 3.8Å; M129-V277 HydrophobicContact CE-CG1 3.87Å; M129-V277 WeakPolarHBondContact CE-O 3.44Å; M129-E279 WeakPolarHBondContact CB-OE1 3.47Å; M129-E279 HydrophobicContact CG-CG 4.2Å; M129-E279 WeakPolarHBondContact CG-OE1 3.46Å; M129-E279 PolarHBondContact N-OE1 3.04Å
130	P	92.1	Very high	90.1	Very high	14 Å²	14	48.4 Å²	48.4	9%	0.091	27%	0.268	C	S	.	.	H	α-helix	trans	-56.2	-42.2	176	-26.2	35.1	0	0	0	112.7	T123 L125 L128 I132 I133 F134	T123-P130 HydrophobicContact CG2-CG 4.22Å; T123-P130 VanDerWaalsContact OG1-CG 3.23Å; T123-P130 WeakPolarHBondContact OG1-CG 3.31Å; L125-P130 HydrophobicContact CB-CG 4.25Å; L128-P130 VanDerWaalsContact C-CD 3.49Å; P130-I132 VanDerWaalsContact C-N 3.32Å; P130-I132 PolarHBondContact O-N 3.05Å; P130-I133 PolarHBondContact O-N 2.9Å; P130-F134 HydrophobicContact CB-CD2 4.25Å; P130-F134 HydrophobicContact CB-CE2 4.29Å; P130-F134 WeakPolarHBondContact O-CB 3.16Å; P130-F134 WeakPolarHBondContact O-CD2 3.5Å; P130-F134 PolarHBondContact O-N 3.1Å
131	W	93.9	Very high	90.7	Very high	71 Å²	71	51.4 Å²	51.4	27%	0.269	28%	0.281	S	S	.	.	H	α-helix	trans	-61.2	-41.8	178.5	-70.9	85.7	0	0	0	112	C116 I117 S120 L128 M129 S135 P177	C116-W131 HydrophobicContact CB-CH2 3.55Å; C116-W131 HydrophobicContact CB-CZ2 4.02Å; C116-W131 HydrophobicContact CB-CZ3 4.3Å; I117-W131 HydrophobicContact CG1-CD2 3.91Å; I117-W131 HydrophobicContact CG1-CE3 4.4Å; I117-W131 HydrophobicContact CG1-CG 4.1Å; I117-W131 HydrophobicContact CG1-CZ2 4.46Å; S120-W131 PolarHBondContact OG-NE1 2.88Å; S120-W131 VanDerWaalsContact OG-NE1 3.15Å; L128-W131 WeakPolarHBondContact O-CB 3.42Å; L128-W131 PolarHBondContact O-N 3.39Å; M129-W131 VanDerWaalsContact C-N 3.28Å; M129-W131 PolarHBondContact O-N 3.48Å; W131-S135 WeakPolarHBondContact O-CB 3.41Å; W131-S135 PolarHBondContact O-N 3.22Å; W131-S135 PolarHBondContact O-OG 3.47Å; W131-P177 HydrophobicContact CB-CB 4.44Å; W131-P177 HydrophobicContact CB-CG 3.9Å
132	I	94.4	Very high	91.5	Very high	0 Å²	0	47.3 Å²	47.3	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-65	-46.4	177.3	-62.2	177.7	0	0	0	110.7	L128 M129 P130 S135 T136 F174 P177 L273 T274	L128-I132 PolarHBondContact O-N 3.03Å; M129-I132 PolarHBondContact O-N 3.29Å; M129-I132 HydrophobicContact SD-CD1 4.34Å; P130-I132 VanDerWaalsContact C-N 3.32Å; P130-I132 PolarHBondContact O-N 3.05Å; I132-S135 PolarHBondContact O-OG 3.36Å; I132-T136 WeakPolarHBondContact O-CB 3.38Å; I132-T136 PolarHBondContact O-N 3.24Å; I132-T136 PolarHBondContact O-OG1 3.25Å; I132-F174 HydrophobicContact CB-CD2 4.43Å; I132-F174 HydrophobicContact CG2-CD2 3.61Å; I132-F174 HydrophobicContact CG2-CE2 3.47Å; I132-F174 VanDerWaalsContact CG2-CE2 3.47Å; I132-F174 HydrophobicContact CG2-CZ 4.27Å; I132-P177 HydrophobicContact CD1-CB 4.48Å; I132-P177 HydrophobicContact CG1-CB 4.23Å; I132-P177 HydrophobicContact CG1-CG 4.09Å; I132-L273 HydrophobicContact CD1-CD2 4.08Å; I132-L273 HydrophobicContact CG2-CD2 4.01Å; I132-T274 HydrophobicContact CG2-CG2 4.3Å
133	I	94.6	Very high	92.1	Very high	64 Å²	64	44.4 Å²	44.4	33%	0.328	24%	0.241	S	C	.	.	H	α-helix	trans	-66.5	-46.2	-177.9	-67.5	164.7	0	0	0	111.2	L125 M129 P130 P137 T274	L125-I133 HydrophobicContact CD1-CD1 4.06Å; M129-I133 WeakPolarHBondContact O-CG1 3.49Å; M129-I133 PolarHBondContact O-N 3.15Å; P130-I133 PolarHBondContact O-N 2.9Å; I133-P137 WeakPolarHBondContact O-CD 3.3Å; I133-T274 HydrophobicContact CD1-CG2 4.04Å; I133-T274 HydrophobicContact CG1-CG2 3.47Å; I133-T274 VanDerWaalsContact CG1-CG2 3.47Å
134	F	94.4	Very high	92.6	Very high	162 Å²	162	45 Å²	45	71%	0.711	24%	0.238	S	C	*	.	H	α-helix	trans	-73.4	-31.8	-177.4	-74.8	-63.6	0	0	0	113.1	P130	P130-F134 HydrophobicContact CB-CD2 4.25Å; P130-F134 HydrophobicContact CB-CE2 4.29Å; P130-F134 WeakPolarHBondContact O-CB 3.16Å; P130-F134 WeakPolarHBondContact O-CD2 3.5Å; P130-F134 PolarHBondContact O-N 3.1Å
135	S	95.4	Very high	93.1	Very high	5 Å²	5	40.1 Å²	40.1	4%	0.035	20%	0.202	C	C	.	.	H	α-helix	trans	-75	-33.8	177.7	57.4	0	0	0	0	113.2	W131 I132 L138 A139 M170	W131-S135 WeakPolarHBondContact O-CB 3.41Å; W131-S135 PolarHBondContact O-N 3.22Å; W131-S135 PolarHBondContact O-OG 3.47Å; I132-S135 PolarHBondContact O-OG 3.36Å; S135-L138 PolarHBondContact O-N 3.02Å; S135-A139 WeakPolarHBondContact O-CB 3.15Å; S135-A139 PolarHBondContact O-N 3.22Å; S135-M170 WeakPolarHBondContact CB-O 3.29Å
136	T	95.8	Very high	93.6	Very high	14 Å²	14	35.1 Å²	35.1	9%	0.086	18%	0.176	C	C	.	.	H	α-helix	trans	-53.1	-52.6	-175.5	-64.2	0	0	0	0	115.1	I132 L138 A139 V140 Y266 A270	I132-T136 WeakPolarHBondContact O-CB 3.38Å; I132-T136 PolarHBondContact O-N 3.24Å; I132-T136 PolarHBondContact O-OG1 3.25Å; T136-L138 VanDerWaalsContact C-N 3.3Å; T136-L138 PolarHBondContact O-N 3.49Å; T136-A139 PolarHBondContact O-N 3.42Å; T136-V140 HydrophobicContact CG2-CG2 4.48Å; T136-V140 WeakPolarHBondContact O-CB 3.35Å; T136-V140 WeakPolarHBondContact O-CG2 3.44Å; T136-V140 PolarHBondContact O-N 3.06Å; T136-Y266 HydrophobicContact CG2-CD1 3.95Å; T136-Y266 HydrophobicContact CG2-CE1 3.8Å; T136-A270 HydrophobicContact CG2-CB 3.77Å
137	P	96.2	Very high	93.9	Very high	76 Å²	76	34.9 Å²	34.9	49%	0.494	17%	0.173	S	C	.	.	H	α-helix	trans	-63.2	-37.3	-178.7	24.1	-33.7	0	0	0	112.2	I133 I141	I133-P137 WeakPolarHBondContact O-CD 3.3Å; P137-I141 WeakPolarHBondContact O-CD1 3.26Å; P137-I141 VanDerWaalsContact O-CG1 3.24Å; P137-I141 WeakPolarHBondContact O-CG1 3.5Å; P137-I141 PolarHBondContact O-N 3.44Å; P137-I141 VanDerWaalsContact O-N 3.12Å
138	L	95.8	Very high	94	Very high	71 Å²	71	38.1 Å²	38.1	37%	0.372	19%	0.188	S	C	.	.	H	α-helix	trans	-74.6	-35.9	-180	-169.2	55.6	0	0	0	111.9	S135 T136 S142 L166 M170	S135-L138 PolarHBondContact O-N 3.02Å; T136-L138 VanDerWaalsContact C-N 3.3Å; T136-L138 PolarHBondContact O-N 3.49Å; L138-S142 WeakPolarHBondContact O-CB 3.35Å; L138-S142 PolarHBondContact O-N 3.5Å; L138-S142 PolarHBondContact O-OG 3.2Å; L138-L166 HydrophobicContact CD1-CD2 4.29Å; L138-L166 HydrophobicContact CD2-CD1 4.27Å; L138-L166 HydrophobicContact CG-CD1 4.47Å; L138-M170 HydrophobicContact CB-CG 3.98Å; L138-M170 HydrophobicContact CB-SD 4.02Å; L138-M170 HydrophobicContact CD2-CE 3.77Å; L138-M170 HydrophobicContact CD2-CG 4.01Å; L138-M170 HydrophobicContact CD2-SD 3.6Å; L138-M170 VanDerWaalsContact CD2-SD 3.6Å; L138-M170 HydrophobicContact CG-CG 3.79Å; L138-M170 HydrophobicContact CG-SD 3.98Å
139	A	95.8	Very high	93.7	Very high	0 Å²	0	39 Å²	39	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-60.7	-46.5	172.1	0	0	0	0	0	111.2	S135 T136 S142 Y143 F167 M170	S135-A139 WeakPolarHBondContact O-CB 3.15Å; S135-A139 PolarHBondContact O-N 3.22Å; T136-A139 PolarHBondContact O-N 3.42Å; A139-S142 WeakPolarHBondContact CA-OG 3.29Å; A139-S142 PolarHBondContact O-N 2.81Å; A139-S142 PolarHBondContact O-OG 3.04Å; A139-Y143 WeakPolarHBondContact O-CB 3.47Å; A139-Y143 PolarHBondContact O-N 3.42Å; A139-F167 WeakPolarHBondContact O-CD2 2.95Å; A139-M170 HydrophobicContact CB-CB 3.7Å
140	V	96.4	Very high	93.3	Very high	19 Å²	19	38.8 Å²	38.8	12%	0.115	19%	0.192	C	C	.	.	H	α-helix	trans	-63.9	-44.9	-179.3	158.9	0	0	0	0	112	T136 F144 V263 Y266 V267	T136-V140 HydrophobicContact CG2-CG2 4.48Å; T136-V140 WeakPolarHBondContact O-CB 3.35Å; T136-V140 WeakPolarHBondContact O-CG2 3.44Å; T136-V140 PolarHBondContact O-N 3.06Å; V140-F144 PolarHBondContact O-N 3.36Å; V140-F144 VanDerWaalsContact O-N 3.1Å; V140-V263 HydrophobicContact CB-CG1 4.41Å; V140-V263 HydrophobicContact CG1-CB 4.13Å; V140-V263 HydrophobicContact CG1-CG1 3.24Å; V140-V263 HydrophobicContact CG1-CG2 3.91Å; V140-V263 HydrophobicContact CG2-CG1 4.47Å; V140-Y266 HydrophobicContact CG2-CD1 3.81Å; V140-Y266 HydrophobicContact CG2-CE1 4.46Å; V140-Y266 HydrophobicContact CG2-CG 3.96Å; V140-V267 HydrophobicContact CG1-CG2 4.35Å; V140-V267 HydrophobicContact CG2-CG2 3.77Å
141	I	96.2	Very high	92.6	Very high	97 Å²	97	44.4 Å²	44.4	50%	0.497	22%	0.222	S	C	.	.	H	α-helix	trans	-64.7	-47.9	178.4	-68.4	165.3	0	0	0	110.3	P137 Y143 F144 L145	P137-I141 WeakPolarHBondContact O-CD1 3.26Å; P137-I141 VanDerWaalsContact O-CG1 3.24Å; P137-I141 WeakPolarHBondContact O-CG1 3.5Å; P137-I141 PolarHBondContact O-N 3.44Å; P137-I141 VanDerWaalsContact O-N 3.12Å; I141-Y143 PolarHBondContact O-N 3.39Å; I141-F144 PolarHBondContact O-N 2.98Å; I141-L145 HydrophobicContact CG2-CD1 3.71Å; I141-L145 HydrophobicContact CG2-CG 4.42Å; I141-L145 VanDerWaalsContact O-CG 3.25Å; I141-L145 WeakPolarHBondContact O-CG 3.48Å; I141-L145 PolarHBondContact O-N 3.24Å; I141-L145 VanDerWaalsContact O-N 3.07Å
142	S	95.9	Very high	91.8	Very high	1 Å²	1	45.2 Å²	45.2	1%	0.007	23%	0.227	C	C	.	.	H	α-helix	trans	-62.1	-41.8	179.2	51.3	0	0	0	0	112.1	L138 A139 F144 L145 I146 F167	L138-S142 WeakPolarHBondContact O-CB 3.35Å; L138-S142 PolarHBondContact O-N 3.5Å; L138-S142 PolarHBondContact O-OG 3.2Å; A139-S142 WeakPolarHBondContact CA-OG 3.29Å; A139-S142 PolarHBondContact O-N 2.81Å; A139-S142 PolarHBondContact O-OG 3.04Å; S142-F144 PolarHBondContact O-N 2.88Å; S142-L145 PolarHBondContact O-N 3.02Å; S142-I146 WeakPolarHBondContact O-CG1 3.38Å; S142-I146 PolarHBondContact O-N 3.4Å; S142-I146 VanDerWaalsContact O-N 3.12Å; S142-F167 WeakPolarHBondContact OG-CA 3.41Å
143	Y	95.7	Very high	90.3	Very high	2 Å²	2	49.3 Å²	49.3	1%	0.008	25%	0.254	C	S	.	.	H	α-helix	trans	-58	-48.2	174.9	-174.2	-99.7	0	0	0	112.3	T59 A62 L63 A139 I141 L145 I146 W147 F167 A259 I262 V263	T59-Y143 HydrophobicContact CG2-CD2 3.95Å; T59-Y143 HydrophobicContact CG2-CE2 3.78Å; T59-Y143 HydrophobicContact CG2-CG 4.4Å; A62-Y143 WeakPolarHBondContact CB-OH 3.5Å; L63-Y143 HydrophobicContact CD1-CD2 4.28Å; L63-Y143 HydrophobicContact CD1-CE2 4.13Å; L63-Y143 HydrophobicContact CD2-CE2 4.09Å; L63-Y143 HydrophobicContact CG-CE2 3.94Å; A139-Y143 WeakPolarHBondContact O-CB 3.47Å; A139-Y143 PolarHBondContact O-N 3.42Å; I141-Y143 PolarHBondContact O-N 3.39Å; Y143-L145 VanDerWaalsContact C-N 3.27Å; Y143-L145 PolarHBondContact O-N 2.99Å; Y143-I146 WeakPolarHBondContact O-CB 3.34Å; Y143-I146 PolarHBondContact O-N 2.99Å; Y143-W147 AromaticContact CE1-CD1 3.88Å; Y143-W147 AromaticContact CE1-NE1 3.57Å; Y143-W147 AromaticContact CE2-NE1 3.6Å; Y143-W147 AromaticContact CZ-NE1 3.25Å; Y143-W147 PolarHBondContact OH-NE1 3.45Å; Y143-F167 HydrophobicContact CD2-CD2 4.13Å; Y143-F167 HydrophobicContact CD2-CE1 4.21Å; Y143-F167 AromaticContact CD2-CE2 3.57Å; Y143-F167 HydrophobicContact CD2-CE2 3.57Å; Y143-F167 AromaticContact CD2-CZ 3.58Å; Y143-F167 HydrophobicContact CD2-CZ 3.58Å; Y143-F167 HydrophobicContact CE2-CZ 4.33Å; Y143-F167 HydrophobicContact CG-CD2 4.39Å; Y143-F167 AromaticContact CG-CE2 3.95Å; Y143-F167 HydrophobicContact CG-CE2 3.95Å; Y143-F167 HydrophobicContact CG-CZ 4.4Å; Y143-A259 HydrophobicContact CD1-CB 4.46Å; Y143-A259 HydrophobicContact CE1-CB 4.01Å; Y143-I262 HydrophobicContact CD1-CG2 4.49Å; Y143-I262 HydrophobicContact CE1-CB 3.99Å; Y143-I262 HydrophobicContact CE1-CG2 3.68Å; Y143-I262 VanDerWaalsContact OH-CD1 3.31Å; Y143-I262 WeakPolarHBondContact OH-CD1 3.35Å; Y143-V263 HydrophobicContact CD1-CG2 3.8Å
144	F	94.9	Very high	88.9	Confident	76 Å²	76	53.3 Å²	53.3	33%	0.333	27%	0.271	S	S	.	.	H	α-helix	trans	-61.8	-37.7	179.4	-171.6	-97.7	0	0	0	112	V140 I141 S142 I146 W147 F148 L256 A259 V263	V140-F144 PolarHBondContact O-N 3.36Å; V140-F144 VanDerWaalsContact O-N 3.1Å; I141-F144 PolarHBondContact O-N 2.98Å; S142-F144 PolarHBondContact O-N 2.88Å; F144-I146 VanDerWaalsContact C-N 3.32Å; F144-I146 PolarHBondContact O-N 3.16Å; F144-W147 PolarHBondContact O-N 3.42Å; F144-F148 PolarHBondContact O-N 3.31Å; F144-L256 HydrophobicContact CD1-CD1 4.48Å; F144-L256 HydrophobicContact CD2-CD1 4.36Å; F144-L256 HydrophobicContact CE1-CD1 3.85Å; F144-L256 HydrophobicContact CE2-CD1 3.7Å; F144-L256 HydrophobicContact CE2-CG 3.98Å; F144-L256 HydrophobicContact CZ-CD1 3.41Å; F144-L256 VanDerWaalsContact CZ-CD1 3.41Å; F144-L256 HydrophobicContact CZ-CD2 4.21Å; F144-L256 HydrophobicContact CZ-CG 3.75Å; F144-A259 HydrophobicContact CD2-CB 4.42Å; F144-V263 HydrophobicContact CB-CG2 4.46Å
145	L	93.1	Very high	88.1	Confident	38 Å²	38	46.1 Å²	46.1	20%	0.199	24%	0.242	C	C	.	.	H	α-helix	trans	-72.3	-20.9	179.7	-66.7	170.4	0	0	0	113.8	I141 S142 Y143 W147 F148 W159 F163	I141-L145 HydrophobicContact CG2-CD1 3.71Å; I141-L145 HydrophobicContact CG2-CG 4.42Å; I141-L145 VanDerWaalsContact O-CG 3.25Å; I141-L145 WeakPolarHBondContact O-CG 3.48Å; I141-L145 PolarHBondContact O-N 3.24Å; I141-L145 VanDerWaalsContact O-N 3.07Å; S142-L145 PolarHBondContact O-N 3.02Å; Y143-L145 VanDerWaalsContact C-N 3.27Å; Y143-L145 PolarHBondContact O-N 2.99Å; L145-W147 VanDerWaalsContact C-N 3.31Å; L145-F148 PolarHBondContact O-N 3.05Å; L145-W159 HydrophobicContact CB-CZ2 4.05Å; L145-W159 HydrophobicContact CD2-CH2 4.19Å; L145-W159 HydrophobicContact CD2-CZ2 3.83Å; L145-W159 HydrophobicContact CG-CZ2 4.38Å; L145-W159 PolarHBondContact O-NE1 3.16Å; L145-W159 VanDerWaalsContact O-NE1 3.09Å; L145-F163 HydrophobicContact CB-CD1 3.84Å; L145-F163 HydrophobicContact CB-CD2 4.27Å; L145-F163 HydrophobicContact CB-CE1 4.11Å; L145-F163 HydrophobicContact CB-CG 3.94Å; L145-F163 HydrophobicContact CB-CZ 4.44Å; L145-F163 HydrophobicContact CD1-CD1 3.77Å; L145-F163 HydrophobicContact CD1-CE1 3.21Å; L145-F163 HydrophobicContact CD1-CE2 4.4Å; L145-F163 HydrophobicContact CD1-CZ 3.59Å; L145-F163 HydrophobicContact CG-CD1 4.47Å; L145-F163 HydrophobicContact CG-CE1 4.28Å
146	I	91.9	Very high	87.4	Confident	2 Å²	2	46.1 Å²	46.1	1%	0.01	24%	0.242	C	C	.	.	H	α-helix	trans	-66	-34.9	170.9	-68.1	166.2	0	0	0	111.1	L63 L67 S142 Y143 F144 F148 Y160 F163 Y164 F167	L63-I146 HydrophobicContact CD2-CD1 4.4Å; L63-I146 HydrophobicContact CD2-CG2 4.05Å; L67-I146 HydrophobicContact CD1-CG2 3.54Å; S142-I146 WeakPolarHBondContact O-CG1 3.38Å; S142-I146 PolarHBondContact O-N 3.4Å; S142-I146 VanDerWaalsContact O-N 3.12Å; Y143-I146 WeakPolarHBondContact O-CB 3.34Å; Y143-I146 PolarHBondContact O-N 2.99Å; F144-I146 VanDerWaalsContact C-N 3.32Å; F144-I146 PolarHBondContact O-N 3.16Å; I146-F148 VanDerWaalsContact C-N 3.33Å; I146-Y160 VanDerWaalsContact O-CE1 3.26Å; I146-Y160 WeakPolarHBondContact O-CE1 3.3Å; I146-F163 HydrophobicContact CG1-CB 4Å; I146-Y164 HydrophobicContact CD1-CD2 4.15Å; I146-F167 HydrophobicContact CD1-CB 3.74Å; I146-F167 HydrophobicContact CD1-CD1 4.25Å; I146-F167 HydrophobicContact CD1-CG 3.98Å
147	W	89.7	Confident	86.7	Confident	2 Å²	2	46.3 Å²	46.3	1%	0.008	24%	0.243	C	C	.	.	T	Hydrogen-bonded Turn	trans	-91.6	2.3	-179.8	-58	102.4	0	0	0	113.3	L63 F66 Y70 Y143 F144 L145 Y255 A259	L63-W147 HydrophobicContact CD2-CZ2 3.79Å; F66-W147 HydrophobicContact CB-CH2 3.98Å; Y70-W147 HydrophobicContact CD1-CE3 4.06Å; Y70-W147 HydrophobicContact CD1-CZ3 4.21Å; Y70-W147 AromaticContact CD2-CE3 3.78Å; Y70-W147 HydrophobicContact CD2-CE3 3.78Å; Y70-W147 AromaticContact CD2-CZ3 3.98Å; Y70-W147 HydrophobicContact CD2-CZ3 3.98Å; Y70-W147 HydrophobicContact CE1-CE3 4.37Å; Y70-W147 HydrophobicContact CE2-CE3 4.08Å; Y70-W147 AromaticContact CG-CE3 3.76Å; Y70-W147 HydrophobicContact CG-CE3 3.76Å; Y70-W147 AromaticContact CG-CZ3 3.68Å; Y70-W147 HydrophobicContact CG-CZ3 3.68Å; Y70-W147 PolarHBondContact OH-O 3.15Å; Y143-W147 AromaticContact CE1-CD1 3.88Å; Y143-W147 AromaticContact CE1-NE1 3.57Å; Y143-W147 AromaticContact CE2-NE1 3.6Å; Y143-W147 AromaticContact CZ-NE1 3.25Å; Y143-W147 PolarHBondContact OH-NE1 3.45Å; F144-W147 PolarHBondContact O-N 3.42Å; L145-W147 VanDerWaalsContact C-N 3.31Å; W147-Y255 HydrophobicContact CD2-CD1 4.34Å; W147-Y255 AromaticContact CE3-CD1 3.34Å; W147-Y255 HydrophobicContact CE3-CD1 3.34Å; W147-Y255 AromaticContact CE3-CE1 3.99Å; W147-Y255 HydrophobicContact CE3-CE1 3.99Å; W147-Y255 HydrophobicContact CE3-CG 4.1Å; W147-Y255 HydrophobicContact CH2-CD1 4.07Å; W147-Y255 HydrophobicContact CH2-CE1 4.02Å; W147-Y255 AromaticContact CZ3-CD1 3.18Å; W147-Y255 HydrophobicContact CZ3-CD1 3.18Å; W147-Y255 AromaticContact CZ3-CE1 3.33Å; W147-Y255 HydrophobicContact CZ3-CE1 3.33Å; W147-Y255 HydrophobicContact CZ3-CG 4.27Å; W147-A259 HydrophobicContact CB-CB 3.86Å; W147-A259 HydrophobicContact CG-CB 3.69Å
148	F	89.4	Confident	86.3	Confident	82 Å²	82	49.7 Å²	49.7	36%	0.36	25%	0.247	S	C	.	.	S	Bend	trans	-91.7	133.1	174.1	-177.7	-100	0	0	0	110.4	F144 L145 I146 P150 W159 Y160	F144-F148 PolarHBondContact O-N 3.31Å; L145-F148 PolarHBondContact O-N 3.05Å; I146-F148 VanDerWaalsContact C-N 3.33Å; F148-P150 VanDerWaalsContact O-CD 3.3Å; F148-P150 WeakPolarHBondContact O-CD 3.13Å; F148-W159 HydrophobicContact CD1-CZ2 4.16Å; F148-Y160 PolarHBondContact O-OH 3.46Å
149	V	84.3	Confident	86	Confident	18 Å²	18	48.8 Å²	48.8	11%	0.109	24%	0.238	C	C	.	.			trans	-91	112.3	175.7	-177.2	0	0	0	0	109	Y70 Q252	Y70-V149 WeakPolarHBondContact OH-CG2 3.22Å; V149-Q252 HydrophobicContact CG2-CG 4.11Å
150	P	82.7	Confident	85.7	Confident	1 Å²	1	48.9 Å²	48.9	1%	0.006	24%	0.239	C	C	.	.			trans	-70.4	144.9	177.7	25.8	-32.4	0	0	0	113.1	F148 F152 Q156 W159	F148-P150 VanDerWaalsContact O-CD 3.3Å; F148-P150 WeakPolarHBondContact O-CD 3.13Å; P150-F152 VanDerWaalsContact C-N 3.34Å; P150-F152 HydrophobicContact CB-CD1 3.86Å; P150-F152 HydrophobicContact CB-CD2 4.23Å; P150-F152 HydrophobicContact CB-CE1 3.28Å; P150-F152 HydrophobicContact CB-CE2 3.69Å; P150-F152 HydrophobicContact CB-CG 4.3Å; P150-F152 HydrophobicContact CB-CZ 3.17Å; P150-F152 HydrophobicContact CG-CE1 4.34Å; P150-F152 HydrophobicContact CG-CE2 3.91Å; P150-F152 HydrophobicContact CG-CZ 3.75Å; P150-F152 PolarHBondContact O-N 2.92Å; P150-Q156 HydrophobicContact CG-CG 4.17Å; P150-Q156 PolarHBondContact O-NE2 3.11Å; P150-W159 HydrophobicContact CB-CD2 4.33Å; P150-W159 HydrophobicContact CB-CG 4.43Å; P150-W159 HydrophobicContact CG-CB 4.23Å; P150-W159 HydrophobicContact CG-CD2 4.28Å; P150-W159 HydrophobicContact CG-CG 3.88Å
151	D	77.4	Confident	85.4	Confident	132 Å²	132	50.6 Å²	50.6	71%	0.706	25%	0.247	S	C	*	.	S	Bend	trans	-81.7	-6.4	-178.4	-76.3	-33.7	0	0	0	114.9	K77	K77-D151 IonicContact NZ-OD1 3.52Å
152	F	77.1	Confident	85.3	Confident	87 Å²	87	51 Å²	51	38%	0.382	25%	0.25	S	C	.	.			trans	-84.9	125.9	178	45	-96	0	0	0	112.2	P150 Q156 W159	P150-F152 VanDerWaalsContact C-N 3.34Å; P150-F152 HydrophobicContact CB-CD1 3.86Å; P150-F152 HydrophobicContact CB-CD2 4.23Å; P150-F152 HydrophobicContact CB-CE1 3.28Å; P150-F152 HydrophobicContact CB-CE2 3.69Å; P150-F152 HydrophobicContact CB-CG 4.3Å; P150-F152 HydrophobicContact CB-CZ 3.17Å; P150-F152 HydrophobicContact CG-CE1 4.34Å; P150-F152 HydrophobicContact CG-CE2 3.91Å; P150-F152 HydrophobicContact CG-CZ 3.75Å; P150-F152 PolarHBondContact O-N 2.92Å; F152-Q156 WeakPolarHBondContact O-CG 3.42Å; F152-W159 AromaticContact CE1-CE3 3.99Å; F152-W159 HydrophobicContact CE1-CE3 3.99Å; F152-W159 HydrophobicContact CE1-CZ3 4.26Å; F152-W159 HydrophobicContact CE2-CB 4.08Å; F152-W159 HydrophobicContact CZ-CB 3.98Å; F152-W159 AromaticContact CZ-CD2 3.85Å; F152-W159 HydrophobicContact CZ-CD2 3.85Å; F152-W159 AromaticContact CZ-CE3 3.42Å; F152-W159 HydrophobicContact CZ-CE3 3.42Å; F152-W159 VanDerWaalsContact CZ-CE3 3.42Å; F152-W159 HydrophobicContact CZ-CG 4.12Å; F152-W159 HydrophobicContact CZ-CZ3 4.15Å
153	P	63.9	Low	85.2	Confident	86 Å²	86	52.3 Å²	52.3	56%	0.558	26%	0.255	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.5	-29.9	-175	24.9	-31.8	0	0	0	114
154	H	65.8	Low	85.1	Confident	149 Å²	149	52.4 Å²	52.4	69%	0.69	26%	0.256	S	S	*	.	T	Hydrogen-bonded Turn	trans	-106.9	49.3	-176.1	-58.7	-52	0	0	0	113	F88	F88-H154 HydrophobicContact CD1-CB 4.25Å; F88-H154 WeakPolarHBondContact CD1-O 3.47Å; F88-H154 VanDerWaalsContact CE1-C 3.45Å; F88-H154 WeakPolarHBondContact CE1-O 3.36Å
155	G	77.1	Confident	85.1	Confident	11 Å²	11	49.5 Å²	49.5	11%	0.113	25%	0.245	C	C	.	.			trans	-166.5	3.4	176.8	0	0	0	0	0	116.8	T157 Y158 W159	G155-T157 PolarHBondContact O-N 3.4Å; G155-Y158 PolarHBondContact O-N 3.13Å; G155-W159 PolarHBondContact O-N 2.97Å
156	Q	80.2	Confident	85.2	Confident	5 Å²	5	50.1 Å²	50.1	2%	0.023	25%	0.248	C	C	.	.	H	α-helix	trans	-63.2	-42.3	-169.2	-58	-170.6	-30.6	0	0	112.1	V90 P150 F152 Y158 W159 Y160	V90-Q156 HydrophobicContact CG2-CB 3.83Å; P150-Q156 HydrophobicContact CG-CG 4.17Å; P150-Q156 PolarHBondContact O-NE2 3.11Å; F152-Q156 WeakPolarHBondContact O-CG 3.42Å; Q156-Y158 VanDerWaalsContact C-N 3.34Å; Q156-Y158 PolarHBondContact O-N 3.36Å; Q156-W159 WeakPolarHBondContact O-CB 2.99Å; Q156-W159 PolarHBondContact O-N 2.89Å; Q156-Y160 HydrophobicContact CB-CE2 4.33Å; Q156-Y160 WeakPolarHBondContact O-CD2 3.24Å; Q156-Y160 PolarHBondContact O-N 3.13Å
157	T	82.1	Confident	85.4	Confident	18 Å²	18	50.1 Å²	50.1	11%	0.11	25%	0.248	C	C	.	.	H	α-helix	trans	-58.1	-44.2	176.3	-53	0	0	0	0	112.2	I98 G155 L161	I98-T157 HydrophobicContact CD1-CG2 4.12Å; I98-T157 HydrophobicContact CG1-CG2 4.26Å; G155-T157 PolarHBondContact O-N 3.4Å; T157-L161 VanDerWaalsContact O-CB 3.29Å; T157-L161 WeakPolarHBondContact O-CB 3.1Å; T157-L161 PolarHBondContact O-N 3.5Å
158	Y	86.8	Confident	85.6	Confident	146 Å²	146	50.7 Å²	50.7	57%	0.573	25%	0.251	S	S	*	.	H	α-helix	trans	-68.5	-36.2	178.5	-68.8	-81.5	0	0	0	112.3	F88 G155 Q156 L162	F88-Y158 HydrophobicContact CD1-CD2 4.15Å; F88-Y158 HydrophobicContact CD1-CE2 4.08Å; F88-Y158 AromaticContact CE1-CD2 3.46Å; F88-Y158 HydrophobicContact CE1-CD2 3.46Å; F88-Y158 VanDerWaalsContact CE1-CD2 3.46Å; F88-Y158 AromaticContact CE1-CE2 3.34Å; F88-Y158 HydrophobicContact CE1-CE2 3.34Å; F88-Y158 AromaticContact CE2-CE2 3.95Å; F88-Y158 HydrophobicContact CE2-CE2 3.95Å; F88-Y158 AromaticContact CZ-CD2 3.89Å; F88-Y158 HydrophobicContact CZ-CD2 3.89Å; F88-Y158 AromaticContact CZ-CE2 3.29Å; F88-Y158 HydrophobicContact CZ-CE2 3.29Å; G155-Y158 PolarHBondContact O-N 3.13Å; Q156-Y158 VanDerWaalsContact C-N 3.34Å; Q156-Y158 PolarHBondContact O-N 3.36Å; Y158-L162 WeakPolarHBondContact O-CB 3.42Å; Y158-L162 PolarHBondContact O-N 3.28Å
159	W	89.4	Confident	85.9	Confident	52 Å²	52	48.3 Å²	48.3	20%	0.197	24%	0.243	C	C	.	.	H	α-helix	trans	-59.2	-54.7	174	176.3	-86.7	0	0	0	111.3	L145 F148 P150 F152 G155 Q156 L161 L162 F163	L145-W159 HydrophobicContact CB-CZ2 4.05Å; L145-W159 HydrophobicContact CD2-CH2 4.19Å; L145-W159 HydrophobicContact CD2-CZ2 3.83Å; L145-W159 HydrophobicContact CG-CZ2 4.38Å; L145-W159 PolarHBondContact O-NE1 3.16Å; L145-W159 VanDerWaalsContact O-NE1 3.09Å; F148-W159 HydrophobicContact CD1-CZ2 4.16Å; P150-W159 HydrophobicContact CB-CD2 4.33Å; P150-W159 HydrophobicContact CB-CG 4.43Å; P150-W159 HydrophobicContact CG-CB 4.23Å; P150-W159 HydrophobicContact CG-CD2 4.28Å; P150-W159 HydrophobicContact CG-CG 3.88Å; F152-W159 AromaticContact CE1-CE3 3.99Å; F152-W159 HydrophobicContact CE1-CE3 3.99Å; F152-W159 HydrophobicContact CE1-CZ3 4.26Å; F152-W159 HydrophobicContact CE2-CB 4.08Å; F152-W159 HydrophobicContact CZ-CB 3.98Å; F152-W159 AromaticContact CZ-CD2 3.85Å; F152-W159 HydrophobicContact CZ-CD2 3.85Å; F152-W159 AromaticContact CZ-CE3 3.42Å; F152-W159 HydrophobicContact CZ-CE3 3.42Å; F152-W159 VanDerWaalsContact CZ-CE3 3.42Å; F152-W159 HydrophobicContact CZ-CG 4.12Å; F152-W159 HydrophobicContact CZ-CZ3 4.15Å; G155-W159 PolarHBondContact O-N 2.97Å; Q156-W159 WeakPolarHBondContact O-CB 2.99Å; Q156-W159 PolarHBondContact O-N 2.89Å; W159-L161 VanDerWaalsContact C-N 3.34Å; W159-L161 PolarHBondContact O-N 3.22Å; W159-L162 PolarHBondContact O-N 3.09Å; W159-F163 AromaticContact CD1-CD2 4Å; W159-F163 AromaticContact CD2-CD2 3.57Å; W159-F163 HydrophobicContact CD2-CD2 3.57Å; W159-F163 AromaticContact CD2-CE2 3.42Å; W159-F163 HydrophobicContact CD2-CE2 3.42Å; W159-F163 VanDerWaalsContact CD2-CE2 3.42Å; W159-F163 AromaticContact CE2-CD2 3.48Å; W159-F163 VanDerWaalsContact CE2-CD2 3.48Å; W159-F163 AromaticContact CE2-CE2 3.45Å; W159-F163 VanDerWaalsContact CE2-CE2 3.45Å; W159-F163 HydrophobicContact CE3-CD2 4.04Å; W159-F163 AromaticContact CE3-CE2 3.38Å; W159-F163 HydrophobicContact CE3-CE2 3.38Å; W159-F163 HydrophobicContact CE3-CZ 4.4Å; W159-F163 AromaticContact CG-CD2 3.93Å; W159-F163 HydrophobicContact CG-CD2 3.93Å; W159-F163 HydrophobicContact CG-CE2 4.21Å; W159-F163 HydrophobicContact CH2-CD2 4.34Å; W159-F163 AromaticContact CH2-CE2 3.5Å; W159-F163 HydrophobicContact CH2-CE2 3.5Å; W159-F163 VanDerWaalsContact CH2-CE2 3.5Å; W159-F163 AromaticContact CH2-CZ 3.94Å; W159-F163 HydrophobicContact CH2-CZ 3.94Å; W159-F163 AromaticContact CZ2-CD2 3.9Å; W159-F163 HydrophobicContact CZ2-CD2 3.9Å; W159-F163 AromaticContact CZ2-CE2 3.51Å; W159-F163 HydrophobicContact CZ2-CE2 3.51Å; W159-F163 HydrophobicContact CZ2-CZ 4.18Å; W159-F163 HydrophobicContact CZ3-CD2 4.41Å; W159-F163 AromaticContact CZ3-CE2 3.44Å; W159-F163 HydrophobicContact CZ3-CE2 3.44Å; W159-F163 VanDerWaalsContact CZ3-CE2 3.44Å; W159-F163 HydrophobicContact CZ3-CZ 4.06Å; W159-F163 AromaticContact NE1-CD2 3.71Å; W159-F163 VanDerWaalsContact O-CD2 3.29Å; W159-F163 WeakPolarHBondContact O-CD2 3.25Å; W159-F163 PolarHBondContact O-N 3.18Å
160	Y	90	Very high	86.4	Confident	3 Å²	3	48.9 Å²	48.9	1%	0.012	25%	0.245	C	C	.	.	H	α-helix	trans	-63.1	-41.1	-179.9	-69.7	-62.8	0	0	0	111.8	Y70 L71 A75 V90 I146 F148 Q156 Y164	Y70-Y160 HydrophobicContact CE1-CE1 4.07Å; L71-Y160 HydrophobicContact CD2-CD1 3.89Å; L71-Y160 HydrophobicContact CD2-CD2 3.88Å; L71-Y160 HydrophobicContact CD2-CE1 4.18Å; L71-Y160 HydrophobicContact CD2-CE2 4.16Å; L71-Y160 HydrophobicContact CD2-CG 3.75Å; A75-Y160 HydrophobicContact CB-CE2 3.97Å; V90-Y160 HydrophobicContact CG2-CD2 4.07Å; V90-Y160 HydrophobicContact CG2-CE2 4.06Å; I146-Y160 VanDerWaalsContact O-CE1 3.26Å; I146-Y160 WeakPolarHBondContact O-CE1 3.3Å; F148-Y160 PolarHBondContact O-OH 3.46Å; Q156-Y160 HydrophobicContact CB-CE2 4.33Å; Q156-Y160 WeakPolarHBondContact O-CD2 3.24Å; Q156-Y160 PolarHBondContact O-N 3.13Å; Y160-Y164 WeakPolarHBondContact O-CB 3.45Å; Y160-Y164 PolarHBondContact O-N 2.96Å
161	L	90.7	Very high	87	Confident	55 Å²	55	49 Å²	49	29%	0.288	25%	0.245	S	C	.	.	H	α-helix	trans	-63.2	-43.9	176.7	-171.1	140.8	0	0	0	112.1	I98 V101 T157 W159 C165	I98-L161 HydrophobicContact CG1-CB 4.46Å; V101-L161 HydrophobicContact CB-CD1 4.37Å; V101-L161 HydrophobicContact CG1-CD1 4.15Å; V101-L161 HydrophobicContact CG1-CG 4.47Å; T157-L161 VanDerWaalsContact O-CB 3.29Å; T157-L161 WeakPolarHBondContact O-CB 3.1Å; T157-L161 PolarHBondContact O-N 3.5Å; W159-L161 VanDerWaalsContact C-N 3.34Å; W159-L161 PolarHBondContact O-N 3.22Å; L161-C165 WeakPolarHBondContact O-CB 3.41Å; L161-C165 PolarHBondContact O-N 3.14Å; L161-C165 PolarHBondContact O-SG 3.36Å
162	L	93.1	Very high	87.8	Confident	106 Å²	106	42.8 Å²	42.8	56%	0.555	21%	0.212	S	C	*	.	H	α-helix	trans	-63.5	-53.3	178.6	178.2	67.9	0	0	0	111.6	Y158 W159 Y164 L166	Y158-L162 WeakPolarHBondContact O-CB 3.42Å; Y158-L162 PolarHBondContact O-N 3.28Å; W159-L162 PolarHBondContact O-N 3.09Å; L162-Y164 VanDerWaalsContact C-N 3.35Å; L162-L166 WeakPolarHBondContact O-CB 3.35Å; L162-L166 PolarHBondContact O-N 3.16Å
163	F	94.1	Very high	88.7	Confident	27 Å²	27	39.2 Å²	39.2	12%	0.118	20%	0.198	C	C	.	.	H	α-helix	trans	-71.1	-32.1	-176.6	-76.2	-68.4	0	0	0	112.5	L145 I146 W159 L166 F167	L145-F163 HydrophobicContact CB-CD1 3.84Å; L145-F163 HydrophobicContact CB-CD2 4.27Å; L145-F163 HydrophobicContact CB-CE1 4.11Å; L145-F163 HydrophobicContact CB-CG 3.94Å; L145-F163 HydrophobicContact CB-CZ 4.44Å; L145-F163 HydrophobicContact CD1-CD1 3.77Å; L145-F163 HydrophobicContact CD1-CE1 3.21Å; L145-F163 HydrophobicContact CD1-CE2 4.4Å; L145-F163 HydrophobicContact CD1-CZ 3.59Å; L145-F163 HydrophobicContact CG-CD1 4.47Å; L145-F163 HydrophobicContact CG-CE1 4.28Å; I146-F163 HydrophobicContact CG1-CB 4Å; W159-F163 AromaticContact CD1-CD2 4Å; W159-F163 AromaticContact CD2-CD2 3.57Å; W159-F163 HydrophobicContact CD2-CD2 3.57Å; W159-F163 AromaticContact CD2-CE2 3.42Å; W159-F163 HydrophobicContact CD2-CE2 3.42Å; W159-F163 VanDerWaalsContact CD2-CE2 3.42Å; W159-F163 AromaticContact CE2-CD2 3.48Å; W159-F163 VanDerWaalsContact CE2-CD2 3.48Å; W159-F163 AromaticContact CE2-CE2 3.45Å; W159-F163 VanDerWaalsContact CE2-CE2 3.45Å; W159-F163 HydrophobicContact CE3-CD2 4.04Å; W159-F163 AromaticContact CE3-CE2 3.38Å; W159-F163 HydrophobicContact CE3-CE2 3.38Å; W159-F163 HydrophobicContact CE3-CZ 4.4Å; W159-F163 AromaticContact CG-CD2 3.93Å; W159-F163 HydrophobicContact CG-CD2 3.93Å; W159-F163 HydrophobicContact CG-CE2 4.21Å; W159-F163 HydrophobicContact CH2-CD2 4.34Å; W159-F163 AromaticContact CH2-CE2 3.5Å; W159-F163 HydrophobicContact CH2-CE2 3.5Å; W159-F163 VanDerWaalsContact CH2-CE2 3.5Å; W159-F163 AromaticContact CH2-CZ 3.94Å; W159-F163 HydrophobicContact CH2-CZ 3.94Å; W159-F163 AromaticContact CZ2-CD2 3.9Å; W159-F163 HydrophobicContact CZ2-CD2 3.9Å; W159-F163 AromaticContact CZ2-CE2 3.51Å; W159-F163 HydrophobicContact CZ2-CE2 3.51Å; W159-F163 HydrophobicContact CZ2-CZ 4.18Å; W159-F163 HydrophobicContact CZ3-CD2 4.41Å; W159-F163 AromaticContact CZ3-CE2 3.44Å; W159-F163 HydrophobicContact CZ3-CE2 3.44Å; W159-F163 VanDerWaalsContact CZ3-CE2 3.44Å; W159-F163 HydrophobicContact CZ3-CZ 4.06Å; W159-F163 AromaticContact NE1-CD2 3.71Å; W159-F163 VanDerWaalsContact O-CD2 3.29Å; W159-F163 WeakPolarHBondContact O-CD2 3.25Å; W159-F163 PolarHBondContact O-N 3.18Å; F163-L166 HydrophobicContact CD1-CD2 4.24Å; F163-L166 HydrophobicContact CE1-CD2 4.34Å; F163-F167 WeakPolarHBondContact O-CB 3.5Å; F163-F167 PolarHBondContact O-N 3.11Å
164	Y	93.3	Very high	90.2	Very high	4 Å²	4	35.1 Å²	35.1	2%	0.016	17%	0.171	C	C	.	.	H	α-helix	trans	-66.6	-50.2	174.1	-171.4	-140.6	0	0	0	111.2	L63 L67 I98 G102 I146 Y160 L162 L166 F167 E168	L63-Y164 HydrophobicContact CD1-CE2 4.24Å; L67-Y164 HydrophobicContact CD2-CD2 4.12Å; L67-Y164 HydrophobicContact CD2-CE1 4.35Å; L67-Y164 HydrophobicContact CD2-CE2 4Å; L67-Y164 HydrophobicContact CD2-CG 4.44Å; I98-Y164 HydrophobicContact CG2-CD1 4.06Å; G102-Y164 VanDerWaalsContact CA-CE1 3.44Å; I146-Y164 HydrophobicContact CD1-CD2 4.15Å; Y160-Y164 WeakPolarHBondContact O-CB 3.45Å; Y160-Y164 PolarHBondContact O-N 2.96Å; L162-Y164 VanDerWaalsContact C-N 3.35Å; Y164-L166 VanDerWaalsContact C-N 3.33Å; Y164-L166 PolarHBondContact O-N 3.47Å; Y164-F167 PolarHBondContact O-N 3.14Å; Y164-E168 HydrophobicContact CD2-CG 4.14Å; Y164-E168 HydrophobicContact CE2-CG 3.79Å; Y164-E168 WeakPolarHBondContact CE2-OE1 3.28Å; Y164-E168 WeakPolarHBondContact O-CG 3.48Å; Y164-E168 PolarHBondContact O-N 3.33Å; Y164-E168 PolarHBondContact OH-OE1 3.35Å
165	C	94.6	Very high	91.5	Very high	16 Å²	16	28.2 Å²	28.2	11%	0.108	14%	0.139	C	C	.	.	H	α-helix	trans	-63.1	-37.9	175.8	-68.7	0	0	0	0	112.7	W105 L161 T169	W105-C165 HydrophobicContact CD2-CB 4.47Å; W105-C165 HydrophobicContact CG-CB 4.09Å; W105-C165 PolarHBondContact NE1-O 3.39Å; L161-C165 WeakPolarHBondContact O-CB 3.41Å; L161-C165 PolarHBondContact O-N 3.14Å; L161-C165 PolarHBondContact O-SG 3.36Å; C165-T169 WeakPolarHBondContact O-CB 3.48Å; C165-T169 PolarHBondContact O-N 3.41Å; C165-T169 PolarHBondContact O-OG1 3.18Å
166	L	95.9	Very high	92.2	Very high	51 Å²	51	27.7 Å²	27.7	27%	0.267	13%	0.134	S	C	.	.	H	α-helix	trans	-63.4	-44.9	176	-178.8	62	0	0	0	111.2	L138 L162 F163 Y164 T169 M170	L138-L166 HydrophobicContact CD1-CD2 4.29Å; L138-L166 HydrophobicContact CD2-CD1 4.27Å; L138-L166 HydrophobicContact CG-CD1 4.47Å; L162-L166 WeakPolarHBondContact O-CB 3.35Å; L162-L166 PolarHBondContact O-N 3.16Å; F163-L166 HydrophobicContact CD1-CD2 4.24Å; F163-L166 HydrophobicContact CE1-CD2 4.34Å; Y164-L166 VanDerWaalsContact C-N 3.33Å; Y164-L166 PolarHBondContact O-N 3.47Å; L166-T169 PolarHBondContact O-N 2.92Å; L166-M170 HydrophobicContact CD1-CE 4.15Å; L166-M170 HydrophobicContact CD1-CG 4.46Å; L166-M170 WeakPolarHBondContact O-CG 3.23Å; L166-M170 PolarHBondContact O-N 3.29Å
167	F	95.9	Very high	92.8	Very high	2 Å²	2	27.5 Å²	27.5	1%	0.009	13%	0.133	C	C	.	.	H	α-helix	trans	-60.6	-51	176.5	175	-101	0	0	0	111.5	T59 L63 A139 S142 Y143 I146 F163 Y164 T169 M170 V171	T59-F167 HydrophobicContact CG2-CZ 4.1Å; L63-F167 HydrophobicContact CD1-CD1 3.57Å; L63-F167 HydrophobicContact CD1-CE1 3.19Å; L63-F167 HydrophobicContact CD1-CZ 4.03Å; A139-F167 WeakPolarHBondContact O-CD2 2.95Å; S142-F167 WeakPolarHBondContact OG-CA 3.41Å; Y143-F167 HydrophobicContact CD2-CD2 4.13Å; Y143-F167 HydrophobicContact CD2-CE1 4.21Å; Y143-F167 AromaticContact CD2-CE2 3.57Å; Y143-F167 HydrophobicContact CD2-CE2 3.57Å; Y143-F167 AromaticContact CD2-CZ 3.58Å; Y143-F167 HydrophobicContact CD2-CZ 3.58Å; Y143-F167 HydrophobicContact CE2-CZ 4.33Å; Y143-F167 HydrophobicContact CG-CD2 4.39Å; Y143-F167 AromaticContact CG-CE2 3.95Å; Y143-F167 HydrophobicContact CG-CE2 3.95Å; Y143-F167 HydrophobicContact CG-CZ 4.4Å; I146-F167 HydrophobicContact CD1-CB 3.74Å; I146-F167 HydrophobicContact CD1-CD1 4.25Å; I146-F167 HydrophobicContact CD1-CG 3.98Å; F163-F167 WeakPolarHBondContact O-CB 3.5Å; F163-F167 PolarHBondContact O-N 3.11Å; Y164-F167 PolarHBondContact O-N 3.14Å; F167-T169 VanDerWaalsContact C-N 3.26Å; F167-T169 PolarHBondContact O-N 3.21Å; F167-M170 PolarHBondContact O-N 2.87Å; F167-M170 VanDerWaalsContact O-N 3.07Å; F167-V171 HydrophobicContact CD1-CG2 4.17Å; F167-V171 HydrophobicContact CD2-CG2 3.93Å; F167-V171 HydrophobicContact CE1-CG2 3.62Å; F167-V171 HydrophobicContact CE2-CG2 3.36Å; F167-V171 HydrophobicContact CG-CG2 4.31Å; F167-V171 HydrophobicContact CZ-CB 4.46Å; F167-V171 HydrophobicContact CZ-CG2 3.21Å; F167-V171 WeakPolarHBondContact O-CB 3.44Å; F167-V171 WeakPolarHBondContact O-CG2 3.46Å; F167-V171 PolarHBondContact O-N 3.42Å
168	E	94.3	Very high	93.4	Very high	14 Å²	14	26.6 Å²	26.6	7%	0.065	13%	0.128	C	C	.	.	H	α-helix	trans	-58.9	-39.2	179.1	-65	-69.2	-166.8	0	0	111.5	D106 Y164 T172	D106-E168 HydrophobicContact CB-CB 3.98Å; D106-E168 HydrophobicContact CB-CG 4.07Å; Y164-E168 HydrophobicContact CD2-CG 4.14Å; Y164-E168 HydrophobicContact CE2-CG 3.79Å; Y164-E168 WeakPolarHBondContact CE2-OE1 3.28Å; Y164-E168 WeakPolarHBondContact O-CG 3.48Å; Y164-E168 PolarHBondContact O-N 3.33Å; Y164-E168 PolarHBondContact OH-OE1 3.35Å; E168-T172 VanDerWaalsContact O-CB 3.3Å; E168-T172 WeakPolarHBondContact O-CB 3.43Å; E168-T172 PolarHBondContact O-N 3.01Å; E168-T172 PolarHBondContact O-OG1 3.18Å
169	T	95.3	Very high	93.6	Very high	31 Å²	31	19.7 Å²	19.7	19%	0.19	10%	0.1	C	C	.	.	H	α-helix	trans	-62.5	-46.3	174.8	-50.2	0	0	0	0	111.8	W105 T109 C165 L166 F167 T172 C173	W105-T169 PolarHBondContact NE1-OG1 2.81Å; T109-T169 HydrophobicContact CG2-CG2 4.27Å; C165-T169 WeakPolarHBondContact O-CB 3.48Å; C165-T169 PolarHBondContact O-N 3.41Å; C165-T169 PolarHBondContact O-OG1 3.18Å; L166-T169 PolarHBondContact O-N 2.92Å; F167-T169 VanDerWaalsContact C-N 3.26Å; F167-T169 PolarHBondContact O-N 3.21Å; T169-T172 WeakPolarHBondContact O-CB 3.46Å; T169-T172 PolarHBondContact O-N 3.46Å; T169-C173 PolarHBondContact O-N 2.92Å; T169-C173 PolarHBondContact O-SG 3.22Å; T169-C173 VanDerWaalsContact O-SG 3.33Å
170	M	95.8	Very high	93.7	Very high	31 Å²	31	17.2 Å²	17.2	15%	0.153	9%	0.091	C	C	.	.	H	α-helix	trans	-71.2	-38	-178	-67.3	-57.5	128	0	0	112.4	S135 L138 A139 L166 F167 T172 C173 F174	S135-M170 WeakPolarHBondContact CB-O 3.29Å; L138-M170 HydrophobicContact CB-CG 3.98Å; L138-M170 HydrophobicContact CB-SD 4.02Å; L138-M170 HydrophobicContact CD2-CE 3.77Å; L138-M170 HydrophobicContact CD2-CG 4.01Å; L138-M170 HydrophobicContact CD2-SD 3.6Å; L138-M170 VanDerWaalsContact CD2-SD 3.6Å; L138-M170 HydrophobicContact CG-CG 3.79Å; L138-M170 HydrophobicContact CG-SD 3.98Å; A139-M170 HydrophobicContact CB-CB 3.7Å; L166-M170 HydrophobicContact CD1-CE 4.15Å; L166-M170 HydrophobicContact CD1-CG 4.46Å; L166-M170 WeakPolarHBondContact O-CG 3.23Å; L166-M170 PolarHBondContact O-N 3.29Å; F167-M170 PolarHBondContact O-N 2.87Å; F167-M170 VanDerWaalsContact O-N 3.07Å; M170-T172 VanDerWaalsContact C-N 3.3Å; M170-C173 CarbonylContact O-C 3.57Å; M170-C173 WeakPolarHBondContact O-CB 3.01Å; M170-C173 PolarHBondContact O-N 3.21Å; M170-F174 PolarHBondContact O-N 2.95Å
171	V	94.3	Very high	93.8	Very high	3 Å²	3	17 Å²	17	2%	0.018	9%	0.09	C	C	.	.	H	α-helix	trans	-63.9	-38.9	172.2	169.1	0	0	0	0	111	Y56 F167 F174 H175	Y56-V171 HydrophobicContact CD2-CG1 3.46Å; Y56-V171 VanDerWaalsContact CD2-CG1 3.46Å; Y56-V171 HydrophobicContact CE2-CG1 3.87Å; F167-V171 HydrophobicContact CD1-CG2 4.17Å; F167-V171 HydrophobicContact CD2-CG2 3.93Å; F167-V171 HydrophobicContact CE1-CG2 3.62Å; F167-V171 HydrophobicContact CE2-CG2 3.36Å; F167-V171 HydrophobicContact CG-CG2 4.31Å; F167-V171 HydrophobicContact CZ-CB 4.46Å; F167-V171 HydrophobicContact CZ-CG2 3.21Å; F167-V171 WeakPolarHBondContact O-CB 3.44Å; F167-V171 WeakPolarHBondContact O-CG2 3.46Å; F167-V171 PolarHBondContact O-N 3.42Å; V171-F174 WeakPolarHBondContact O-CB 3.41Å; V171-F174 PolarHBondContact O-N 3.01Å; V171-F174 VanDerWaalsContact O-N 3.09Å; V171-H175 WeakPolarHBondContact O-CB 3.35Å; V171-H175 PolarHBondContact O-N 2.76Å
172	T	94.1	Very high	93.7	Very high	1 Å²	1	14.5 Å²	14.5	1%	0.006	8%	0.077	C	C	.	.	H	α-helix	trans	-60.1	-46.7	172	-60.5	0	0	0	0	111.2	D106 T109 D110 V113 E168 T169 M170 F174 H175 V176	D106-T172 PolarHBondContact OD1-OG1 3.35Å; T109-T172 PolarHBondContact OG1-OG1 3.23Å; T109-T172 VanDerWaalsContact OG1-OG1 3.08Å; D110-T172 WeakPolarHBondContact OD1-CG2 3.46Å; V113-T172 HydrophobicContact CB-CG2 3.82Å; V113-T172 HydrophobicContact CG1-CG2 4.23Å; V113-T172 HydrophobicContact CG2-CG2 3.71Å; E168-T172 VanDerWaalsContact O-CB 3.3Å; E168-T172 WeakPolarHBondContact O-CB 3.43Å; E168-T172 PolarHBondContact O-N 3.01Å; E168-T172 PolarHBondContact O-OG1 3.18Å; T169-T172 WeakPolarHBondContact O-CB 3.46Å; T169-T172 PolarHBondContact O-N 3.46Å; M170-T172 VanDerWaalsContact C-N 3.3Å; T172-F174 PolarHBondContact O-N 3.32Å; T172-F174 VanDerWaalsContact O-N 3.14Å; T172-H175 PolarHBondContact O-N 2.84Å; T172-V176 HydrophobicContact CG2-CG2 3.77Å; T172-V176 WeakPolarHBondContact O-CB 3.34Å; T172-V176 WeakPolarHBondContact O-CG2 3.44Å; T172-V176 PolarHBondContact O-N 3.31Å
173	C	95.2	Very high	93.5	Very high	13 Å²	13	10.1 Å²	10.1	9%	0.088	5%	0.054	C	C	.	.	H	α-helix	trans	-60.9	-17.1	174.6	-72.4	0	0	0	0	114.1	T169 M170 P177	T169-C173 PolarHBondContact O-N 2.92Å; T169-C173 PolarHBondContact O-SG 3.22Å; T169-C173 VanDerWaalsContact O-SG 3.33Å; M170-C173 CarbonylContact O-C 3.57Å; M170-C173 WeakPolarHBondContact O-CB 3.01Å; M170-C173 PolarHBondContact O-N 3.21Å; C173-P177 WeakPolarHBondContact O-CD 3.1Å; C173-P177 WeakPolarHBondContact O-CG 3.36Å
174	F	95.4	Very high	93.3	Very high	0 Å²	0	9.1 Å²	9.1	0%	0	5%	0.05	C	C	.	.	H	α-helix	trans	-92.9	-53.3	173	-179.3	-80.2	0	0	0	111.4	G52 P55 I132 M170 V171 T172 P177 Y178 Y266 A270 L273	G52-F174 WeakPolarHBondContact O-CE1 3.45Å; P55-F174 HydrophobicContact CB-CE1 4.33Å; P55-F174 HydrophobicContact CB-CZ 4.35Å; P55-F174 HydrophobicContact CG-CE1 4.47Å; P55-F174 HydrophobicContact CG-CZ 4.16Å; I132-F174 HydrophobicContact CB-CD2 4.43Å; I132-F174 HydrophobicContact CG2-CD2 3.61Å; I132-F174 HydrophobicContact CG2-CE2 3.47Å; I132-F174 VanDerWaalsContact CG2-CE2 3.47Å; I132-F174 HydrophobicContact CG2-CZ 4.27Å; M170-F174 PolarHBondContact O-N 2.95Å; V171-F174 WeakPolarHBondContact O-CB 3.41Å; V171-F174 PolarHBondContact O-N 3.01Å; V171-F174 VanDerWaalsContact O-N 3.09Å; T172-F174 PolarHBondContact O-N 3.32Å; T172-F174 VanDerWaalsContact O-N 3.14Å; F174-P177 WeakPolarHBondContact O-CD 3.43Å; F174-Y178 WeakPolarHBondContact O-CB 3.47Å; F174-Y178 PolarHBondContact O-N 3.23Å; F174-Y266 HydrophobicContact CD2-CE1 4.13Å; F174-Y266 WeakPolarHBondContact CD2-OH 3.32Å; F174-Y266 HydrophobicContact CE2-CE1 4.06Å; F174-Y266 WeakPolarHBondContact CG-OH 3.19Å; F174-A270 HydrophobicContact CE2-CB 4Å; F174-L273 HydrophobicContact CZ-CD2 4.21Å
175	H	93.6	Very high	93	Very high	4 Å²	4	9.1 Å²	9.1	2%	0.019	5%	0.05	C	C	.	.	H	α-helix	trans	-72.2	-39.3	-169	176	-102.6	0	0	0	113.6	Y56 V171 T172 Y178 S179	Y56-H175 AromaticContact CD1-CD2 3.5Å; Y56-H175 VanDerWaalsContact CD1-CD2 3.5Å; Y56-H175 WeakPolarHBondContact CD1-CD2 3.4Å; Y56-H175 AromaticContact CD1-NE2 3.71Å; Y56-H175 HydrophobicContact CD2-CB 3.87Å; Y56-H175 AromaticContact CD2-CD2 3.92Å; Y56-H175 AromaticContact CD2-CG 3.83Å; Y56-H175 AromaticContact CE1-CD2 3.89Å; Y56-H175 AromaticContact CE1-NE2 3.73Å; Y56-H175 HydrophobicContact CE2-CB 4.27Å; Y56-H175 HydrophobicContact CG-CB 4.25Å; Y56-H175 AromaticContact CG-CD2 3.52Å; Y56-H175 AromaticContact CG-CG 3.93Å; V171-H175 WeakPolarHBondContact O-CB 3.35Å; V171-H175 PolarHBondContact O-N 2.76Å; T172-H175 PolarHBondContact O-N 2.84Å; H175-Y178 PolarHBondContact O-N 2.99Å; H175-S179 PolarHBondContact CE1-OG 3.07Å; H175-S179 PolarHBondContact NE2-OG 3.41Å; H175-S179 VanDerWaalsContact O-CB 3.3Å; H175-S179 WeakPolarHBondContact O-CB 3.31Å; H175-S179 PolarHBondContact O-N 2.91Å; H175-S179 PolarHBondContact O-OG 3.49Å
176	V	92.4	Very high	92.7	Very high	0 Å²	0	8.5 Å²	8.5	0%	0	5%	0.046	C	C	.	.	H	α-helix	trans	-63.4	-53.1	178.6	174.5	0	0	0	0	111.7	V113 I117 T172 Y178 S179 A180	V113-V176 HydrophobicContact CG1-CB 4.15Å; V113-V176 HydrophobicContact CG1-CG1 4.42Å; I117-V176 HydrophobicContact CD1-CB 4.41Å; I117-V176 HydrophobicContact CD1-CG1 3.98Å; T172-V176 HydrophobicContact CG2-CG2 3.77Å; T172-V176 WeakPolarHBondContact O-CB 3.34Å; T172-V176 WeakPolarHBondContact O-CG2 3.44Å; T172-V176 PolarHBondContact O-N 3.31Å; V176-Y178 VanDerWaalsContact C-N 3.32Å; V176-Y178 PolarHBondContact O-N 2.93Å; V176-S179 PolarHBondContact O-N 3.08Å; V176-A180 PolarHBondContact O-N 2.78Å
177	P	92.8	Very high	92.1	Very high	0 Å²	0	8.1 Å²	8.1	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-65	-35.8	175.5	13.5	-16.1	0	0	0	112.2	I117 L128 W131 I132 C173 F174 S179 A180 L181	I117-P177 HydrophobicContact CD1-CB 3.79Å; I117-P177 HydrophobicContact CD1-CG 3.64Å; L128-P177 HydrophobicContact CB-CB 3.96Å; L128-P177 HydrophobicContact CD2-CB 4.01Å; W131-P177 HydrophobicContact CB-CB 4.44Å; W131-P177 HydrophobicContact CB-CG 3.9Å; I132-P177 HydrophobicContact CD1-CB 4.48Å; I132-P177 HydrophobicContact CG1-CB 4.23Å; I132-P177 HydrophobicContact CG1-CG 4.09Å; C173-P177 WeakPolarHBondContact O-CD 3.1Å; C173-P177 WeakPolarHBondContact O-CG 3.36Å; F174-P177 WeakPolarHBondContact O-CD 3.43Å; P177-S179 VanDerWaalsContact C-N 3.34Å; P177-S179 PolarHBondContact O-N 2.51Å; P177-A180 PolarHBondContact O-N 3.19Å; P177-L181 WeakPolarHBondContact O-CB 3.29Å; P177-L181 PolarHBondContact O-N 3.2Å
178	Y	94.4	Very high	91.6	Very high	0 Å²	0	9.8 Å²	9.8	0%	0	5%	0.053	C	C	.	.	H	α-helix	trans	-60	-41.9	174.3	171.4	-109.8	0	0	0	113.1	Y49 A50 G53 F174 H175 V176 L181 R199 L273	Y49-Y178 AromaticContact CD2-CE2 3.88Å; Y49-Y178 HydrophobicContact CD2-CE2 3.88Å; Y49-Y178 HydrophobicContact CE2-CD2 4.13Å; Y49-Y178 AromaticContact CE2-CE2 3.58Å; Y49-Y178 HydrophobicContact CE2-CE2 3.58Å; Y49-Y178 WeakPolarHBondContact O-CE2 3.48Å; Y49-Y178 PolarHBondContact O-OH 2.76Å; Y49-Y178 PolarHBondContact OH-O 3.33Å; A50-Y178 PolarHBondContact O-OH 3.25Å; G53-Y178 WeakPolarHBondContact CA-OH 3.1Å; G53-Y178 PolarHBondContact N-OH 3.09Å; F174-Y178 WeakPolarHBondContact O-CB 3.47Å; F174-Y178 PolarHBondContact O-N 3.23Å; H175-Y178 PolarHBondContact O-N 2.99Å; V176-Y178 VanDerWaalsContact C-N 3.32Å; V176-Y178 PolarHBondContact O-N 2.93Å; Y178-L181 VanDerWaalsContact O-CB 3.25Å; Y178-L181 WeakPolarHBondContact O-CB 3.47Å; Y178-L181 PolarHBondContact O-N 3Å; Y178-R199 VanDerWaalsContact CE1-CD 3.44Å; Y178-R199 HydrophobicContact CE1-CG 4.11Å; Y178-R199 WeakPolarHBondContact OH-CD 3.34Å; Y178-R199 VanDerWaalsContact OH-CG 3.23Å; Y178-R199 WeakPolarHBondContact OH-CG 3.33Å; Y178-L273 HydrophobicContact CD2-CD1 4.14Å; Y178-L273 HydrophobicContact CD2-CD2 3.73Å; Y178-L273 HydrophobicContact CE2-CD1 3.98Å; Y178-L273 HydrophobicContact CE2-CD2 4.21Å
179	S	91.4	Very high	91.2	Very high	0 Å²	0	10 Å²	10	0%	0	6%	0.055	C	C	.	.	H	α-helix	trans	-66.4	-43.4	175.4	-69.6	0	0	0	0	111.7	H175 V176 P177 L181 T182	H175-S179 PolarHBondContact CE1-OG 3.07Å; H175-S179 PolarHBondContact NE2-OG 3.41Å; H175-S179 VanDerWaalsContact O-CB 3.3Å; H175-S179 WeakPolarHBondContact O-CB 3.31Å; H175-S179 PolarHBondContact O-N 2.91Å; H175-S179 PolarHBondContact O-OG 3.49Å; V176-S179 PolarHBondContact O-N 3.08Å; P177-S179 VanDerWaalsContact C-N 3.34Å; P177-S179 PolarHBondContact O-N 2.51Å; S179-L181 PolarHBondContact O-N 3.29Å; S179-T182 PolarHBondContact O-N 3.07Å; S179-T182 PolarHBondContact O-OG1 3.25Å; S179-T182 VanDerWaalsContact O-OG1 3.12Å
180	A	91	Very high	90.8	Very high	0 Å²	0	12 Å²	12	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-66	-26.6	177.1	0	0	0	0	0	112.9	L128 V176 P177 T182 M183 F184 P438 F441	L128-A180 HydrophobicContact CD1-CB 4.17Å; V176-A180 PolarHBondContact O-N 2.78Å; P177-A180 PolarHBondContact O-N 3.19Å; A180-T182 PolarHBondContact O-N 3.32Å; A180-M183 PolarHBondContact O-N 2.63Å; A180-F184 WeakPolarHBondContact O-CD2 3.46Å; A180-P438 HydrophobicContact CB-CB 4.43Å; A180-P438 HydrophobicContact CB-CG 4.36Å; A180-F441 HydrophobicContact CB-CD2 3.96Å; A180-F441 HydrophobicContact CB-CG 4.45Å
181	L	91.4	Very high	90.6	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-57.2	-22.5	-180	-169.9	65.3	0	0	0	113.1	Y49 L128 M129 P177 Y178 S179 M183 F184 I185 L273 V277 E279	Y49-L181 HydrophobicContact CD2-CD2 3.99Å; Y49-L181 HydrophobicContact CD2-CG 4.44Å; Y49-L181 HydrophobicContact CE2-CB 4.11Å; Y49-L181 HydrophobicContact CE2-CD2 4.03Å; Y49-L181 HydrophobicContact CE2-CG 4.21Å; L128-L181 HydrophobicContact CD1-CB 4.14Å; L128-L181 HydrophobicContact CD1-CD1 4.05Å; M129-L181 HydrophobicContact CE-CD1 4.09Å; M129-L181 HydrophobicContact CE-CD2 3.63Å; P177-L181 WeakPolarHBondContact O-CB 3.29Å; P177-L181 PolarHBondContact O-N 3.2Å; Y178-L181 VanDerWaalsContact O-CB 3.25Å; Y178-L181 WeakPolarHBondContact O-CB 3.47Å; Y178-L181 PolarHBondContact O-N 3Å; S179-L181 PolarHBondContact O-N 3.29Å; L181-M183 PolarHBondContact O-N 3.31Å; L181-F184 HydrophobicContact CD1-CB 4.33Å; L181-F184 PolarHBondContact O-N 3.04Å; L181-I185 PolarHBondContact O-N 3.1Å; L181-L273 HydrophobicContact CD2-CD1 4.15Å; L181-V277 HydrophobicContact CD2-CG1 3.97Å; L181-V277 HydrophobicContact CG-CG1 4.43Å; L181-E279 HydrophobicContact CD1-CG 3.57Å
182	T	90.4	Very high	90.4	Very high	1 Å²	1	11.6 Å²	11.6	1%	0.006	6%	0.064	C	C	.	.	H	α-helix	trans	-54.9	-33.1	171.9	-46.5	0	0	0	0	112.2	Y49 S179 A180 I185 R192	Y49-T182 PolarHBondContact OH-OG1 3.36Å; S179-T182 PolarHBondContact O-N 3.07Å; S179-T182 PolarHBondContact O-OG1 3.25Å; S179-T182 VanDerWaalsContact O-OG1 3.12Å; A180-T182 PolarHBondContact O-N 3.32Å; T182-I185 WeakPolarHBondContact O-CG2 3.23Å; T182-R192 HydrophobicContact CG2-CB 4.07Å; T182-R192 HydrophobicContact CG2-CG 4.49Å; T182-R192 WeakPolarHBondContact O-CG 3.48Å
183	M	88.8	Confident	90.3	Very high	14 Å²	14	12.1 Å²	12.1	7%	0.069	7%	0.067	C	C	.	.	H	α-helix	trans	-77	-27	178.7	-68	-62	-70.4	0	0	113	A180 L181 R192 P420 I423 F441	A180-M183 PolarHBondContact O-N 2.63Å; L181-M183 PolarHBondContact O-N 3.31Å; M183-R192 VanDerWaalsContact CE-NH1 3.28Å; M183-R192 PolarHBondContact O-NH2 2.73Å; M183-P420 HydrophobicContact SD-CB 3.56Å; M183-P420 VanDerWaalsContact SD-CB 3.56Å; M183-P420 HydrophobicContact SD-CG 4Å; M183-I423 HydrophobicContact CE-CB 4.07Å; M183-I423 HydrophobicContact CE-CG2 3.75Å; M183-I423 HydrophobicContact CG-CD1 4.33Å; M183-I423 HydrophobicContact SD-CD1 4.49Å; M183-F441 HydrophobicContact CG-CE2 3.73Å; M183-F441 HydrophobicContact CG-CZ 4.14Å
184	F	87.9	Confident	90.1	Very high	7 Å²	7	12.4 Å²	12.4	3%	0.031	7%	0.069	C	C	.	.	H	α-helix	trans	-97.7	-8.9	-174.3	-64	-83.1	0	0	0	113.8	W122 L128 A180 L181 Q280 E437	W122-F184 HydrophobicContact CH2-CD1 4.02Å; W122-F184 HydrophobicContact CH2-CE1 4.43Å; W122-F184 HydrophobicContact CZ2-CD1 4.19Å; W122-F184 HydrophobicContact CZ2-CE1 4.14Å; L128-F184 HydrophobicContact CD1-CB 4.48Å; L128-F184 HydrophobicContact CD1-CD2 3.39Å; L128-F184 HydrophobicContact CD1-CE2 3.96Å; L128-F184 HydrophobicContact CD1-CG 4.04Å; L128-F184 HydrophobicContact CG-CD2 4.44Å; A180-F184 WeakPolarHBondContact O-CD2 3.46Å; L181-F184 HydrophobicContact CD1-CB 4.33Å; L181-F184 PolarHBondContact O-N 3.04Å; F184-Q280 WeakPolarHBondContact O-CB 3.35Å; F184-Q280 PolarHBondContact O-N 3.46Å; F184-E437 HydrophobicContact CE2-CB 4.35Å; F184-E437 HydrophobicContact CE2-CG 4.46Å; F184-E437 HydrophobicContact CZ-CG 4.2Å
185	I	88.3	Confident	90	Very high	4 Å²	4	12.4 Å²	12.4	2%	0.021	7%	0.069	C	C	.	.	H	α-helix	trans	-82.9	-33.1	-180	-162.7	172.3	0	0	0	112.8	L41 Y49 L181 T182 V277	L41-I185 HydrophobicContact CD1-CD1 4.12Å; L41-I185 HydrophobicContact CD1-CG1 3.89Å; L41-I185 HydrophobicContact CD1-CG2 4.09Å; L41-I185 HydrophobicContact CD2-CG1 4Å; Y49-I185 HydrophobicContact CD2-CD1 4.2Å; Y49-I185 HydrophobicContact CG-CD1 3.92Å; L181-I185 PolarHBondContact O-N 3.1Å; T182-I185 WeakPolarHBondContact O-CG2 3.23Å; I185-V277 HydrophobicContact CD1-CG1 3.85Å; I185-V277 HydrophobicContact CG1-CG1 4.09Å
186	S	88.9	Confident	90	Very high	3 Å²	3	12.2 Å²	12.2	2%	0.021	7%	0.068	C	C	.	.			trans	-153.4	151.8	178.3	-176.6	0	0	0	0	110.5	E188 E191 R192	S186-E188 PolarHBondContact OG-N 3.25Å; S186-E191 WeakPolarHBondContact OG-CB 3.18Å; S186-R192 VanDerWaalsContact O-CZ 3.29Å; S186-R192 PolarHBondContact O-NE 2.91Å; S186-R192 PolarHBondContact O-NH2 3.1Å; S186-R192 VanDerWaalsContact O-NH2 3.1Å
187	T	81.9	Confident	90.1	Very high	42 Å²	42	12.6 Å²	12.6	26%	0.258	7%	0.071	S	C	.	.	S	Bend	trans	-89.3	-11.2	175.7	56.4	0	0	0	0	113.1	E282 R523	T187-E282 HydrophobicContact CG2-CG 4.33Å; T187-E282 VanDerWaalsContact CG2-OE1 3.23Å; T187-E282 WeakPolarHBondContact CG2-OE1 3.27Å; T187-R523 PolarHBondContact O-NH1 2.71Å; T187-R523 PolarHBondContact O-NH2 2.7Å
188	E	86	Confident	90.2	Very high	38 Å²	38	17.1 Å²	17.1	18%	0.178	9%	0.088	C	C	.	.			trans	-95.7	121.1	-177.4	-74.1	-69	159.9	0	0	111.2	S186 T190 E191 R192 K516	S186-E188 PolarHBondContact OG-N 3.25Å; E188-T190 VanDerWaalsContact C-N 3.28Å; E188-T190 PolarHBondContact O-N 3.45Å; E188-E191 HydrophobicContact CB-CB 4.17Å; E188-E191 HydrophobicContact CB-CG 3.92Å; E188-E191 WeakPolarHBondContact O-CB 3.38Å; E188-E191 PolarHBondContact O-N 3.17Å; E188-R192 PolarHBondContact O-N 3.45Å; E188-K516 VanDerWaalsContact OE2-CE 3.23Å; E188-K516 WeakPolarHBondContact OE2-CE 3.19Å; E188-K516 IonicContact OE2-NZ 3.56Å; E188-K516 PolarHBondContact OE2-NZ 3.43Å
189	Q	86.1	Confident	90.2	Very high	19 Å²	19	17.1 Å²	17.1	9%	0.089	9%	0.088	C	C	.	.	H	α-helix	trans	-54.4	-40.7	-179	-70.6	171.7	-12	0	0	113.2	E191 R192 D193 D424	Q189-E191 VanDerWaalsContact C-N 3.31Å; Q189-E191 PolarHBondContact O-N 2.89Å; Q189-R192 PolarHBondContact O-N 2.99Å; Q189-D193 VanDerWaalsContact O-CG 3.25Å; Q189-D193 PolarHBondContact O-N 3.45Å; Q189-D424 PolarHBondContact NE2-OD2 2.7Å
190	T	87.1	Confident	90.3	Very high	72 Å²	72	17.2 Å²	17.2	44%	0.442	9%	0.089	S	C	.	.	H	α-helix	trans	-65.7	-34	179.3	52.6	0	0	0	0	112.7	E188 S194	E188-T190 VanDerWaalsContact C-N 3.28Å; E188-T190 PolarHBondContact O-N 3.45Å; T190-S194 WeakPolarHBondContact O-CB 3.33Å; T190-S194 PolarHBondContact O-N 3.09Å; T190-S194 VanDerWaalsContact O-N 3.1Å; T190-S194 PolarHBondContact O-OG 3.34Å
191	E	90.5	Very high	90.5	Very high	22 Å²	22	18.7 Å²	18.7	10%	0.103	10%	0.098	C	C	.	.	H	α-helix	trans	-72.3	-42.9	176.6	-66.2	-61.7	134.2	0	0	110.3	L41 K46 S186 E188 Q189 S194 A195	L41-E191 HydrophobicContact CD1-CB 4.25Å; L41-E191 PolarHBondContact N-OE2 3.27Å; L41-E191 VanDerWaalsContact N-OE2 3.16Å; K46-E191 WeakPolarHBondContact CE-OE2 3.27Å; K46-E191 IonicContact NZ-OE1 3.46Å; K46-E191 IonicContact NZ-OE2 2.76Å; K46-E191 PolarHBondContact NZ-OE2 3.03Å; S186-E191 WeakPolarHBondContact OG-CB 3.18Å; E188-E191 HydrophobicContact CB-CB 4.17Å; E188-E191 HydrophobicContact CB-CG 3.92Å; E188-E191 WeakPolarHBondContact O-CB 3.38Å; E188-E191 PolarHBondContact O-N 3.17Å; Q189-E191 VanDerWaalsContact C-N 3.31Å; Q189-E191 PolarHBondContact O-N 2.89Å; E191-S194 PolarHBondContact O-N 3.01Å; E191-S194 PolarHBondContact O-OG 3.36Å; E191-A195 WeakPolarHBondContact O-CB 3.42Å; E191-A195 PolarHBondContact O-N 3.36Å
192	R	91.1	Very high	90.7	Very high	4 Å²	4	19.7 Å²	19.7	2%	0.015	10%	0.104	C	C	.	.	H	α-helix	trans	-57.5	-49.8	173.2	-65	-177.3	-179.5	161.1	-4.6	111.7	T182 M183 S186 E188 Q189 S194 A195 T196 D424	T182-R192 HydrophobicContact CG2-CB 4.07Å; T182-R192 HydrophobicContact CG2-CG 4.49Å; T182-R192 WeakPolarHBondContact O-CG 3.48Å; M183-R192 VanDerWaalsContact CE-NH1 3.28Å; M183-R192 PolarHBondContact O-NH2 2.73Å; S186-R192 VanDerWaalsContact O-CZ 3.29Å; S186-R192 PolarHBondContact O-NE 2.91Å; S186-R192 PolarHBondContact O-NH2 3.1Å; S186-R192 VanDerWaalsContact O-NH2 3.1Å; E188-R192 PolarHBondContact O-N 3.45Å; Q189-R192 PolarHBondContact O-N 2.99Å; R192-S194 VanDerWaalsContact C-N 3.3Å; R192-S194 PolarHBondContact O-N 2.97Å; R192-A195 PolarHBondContact O-N 3.46Å; R192-T196 PolarHBondContact O-N 3.37Å; R192-T196 PolarHBondContact O-OG1 2.7Å; R192-T196 VanDerWaalsContact O-OG1 3.09Å; R192-D424 IonicContact NH1-OD1 2.87Å; R192-D424 PolarHBondContact NH1-OD1 2.91Å; R192-D424 VanDerWaalsContact NH1-OD1 3.08Å; R192-D424 IonicContact NH1-OD2 3.91Å
193	D	91.3	Very high	90.8	Very high	12 Å²	12	20 Å²	20	6%	0.064	11%	0.105	C	C	.	.	H	α-helix	trans	-58.9	-43.3	178.1	-70	-29	0	0	0	111.2	Q189 T196 A197 Q361 K369 S417	Q189-D193 VanDerWaalsContact O-CG 3.25Å; Q189-D193 PolarHBondContact O-N 3.45Å; D193-T196 PolarHBondContact O-N 2.8Å; D193-A197 PolarHBondContact O-N 3.33Å; D193-Q361 PolarHBondContact O-NE2 3.06Å; D193-Q361 PolarHBondContact O-OE1 3.29Å; D193-K369 VanDerWaalsContact CG-NZ 3.32Å; D193-K369 WeakPolarHBondContact OD1-CE 3.45Å; D193-K369 IonicContact OD1-NZ 2.68Å; D193-K369 PolarHBondContact OD1-NZ 3.35Å; D193-K369 WeakPolarHBondContact OD2-CE 3.43Å; D193-K369 IonicContact OD2-NZ 3.08Å; D193-K369 PolarHBondContact OD2-NZ 3.38Å; D193-S417 VanDerWaalsContact CG-OG 3.3Å; D193-S417 PolarHBondContact OD1-OG 3.04Å
194	S	92.3	Very high	91	Very high	18 Å²	18	19.9 Å²	19.9	13%	0.126	11%	0.105	C	C	.	.	H	α-helix	trans	-64.3	-44.6	177	74.7	0	0	0	0	111.7	K46 T190 E191 R192 T196 A197 Y198 Q361	K46-S194 WeakPolarHBondContact CE-OG 3.5Å; K46-S194 PolarHBondContact NZ-OG 3.12Å; T190-S194 WeakPolarHBondContact O-CB 3.33Å; T190-S194 PolarHBondContact O-N 3.09Å; T190-S194 VanDerWaalsContact O-N 3.1Å; T190-S194 PolarHBondContact O-OG 3.34Å; E191-S194 PolarHBondContact O-N 3.01Å; E191-S194 PolarHBondContact O-OG 3.36Å; R192-S194 VanDerWaalsContact C-N 3.3Å; R192-S194 PolarHBondContact O-N 2.97Å; S194-T196 VanDerWaalsContact C-N 3.29Å; S194-T196 PolarHBondContact O-N 3.08Å; S194-A197 WeakPolarHBondContact O-CB 3.36Å; S194-A197 PolarHBondContact O-N 3.16Å; S194-A197 VanDerWaalsContact O-N 3.09Å; S194-Y198 VanDerWaalsContact O-CD2 3.29Å; S194-Y198 WeakPolarHBondContact O-CD2 3.43Å; S194-Y198 PolarHBondContact O-N 3.44Å; S194-Y198 VanDerWaalsContact O-N 3.08Å; S194-Q361 VanDerWaalsContact N-NE2 3.19Å
195	A	92.9	Very high	91.2	Very high	0 Å²	0	23.2 Å²	23.2	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-60.7	-39.6	177.6	0	0	0	0	0	111.6	Y49 E191 R192 Y198 R199	Y49-A195 HydrophobicContact CD1-CB 3.88Å; Y49-A195 HydrophobicContact CE1-CB 4.06Å; E191-A195 WeakPolarHBondContact O-CB 3.42Å; E191-A195 PolarHBondContact O-N 3.36Å; R192-A195 PolarHBondContact O-N 3.46Å; A195-Y198 PolarHBondContact O-N 3.14Å; A195-R199 WeakPolarHBondContact O-CB 3.33Å; A195-R199 PolarHBondContact O-N 3.32Å
196	T	93.3	Very high	91.4	Very high	1 Å²	1	23.2 Å²	23.2	1%	0.006	12%	0.124	C	C	.	.	H	α-helix	trans	-61.4	-41.4	173	-60	0	0	0	0	112	R192 D193 S194 R199 M200 L413 W416	R192-T196 PolarHBondContact O-N 3.37Å; R192-T196 PolarHBondContact O-OG1 2.7Å; R192-T196 VanDerWaalsContact O-OG1 3.09Å; D193-T196 PolarHBondContact O-N 2.8Å; S194-T196 VanDerWaalsContact C-N 3.29Å; S194-T196 PolarHBondContact O-N 3.08Å; T196-R199 WeakPolarHBondContact O-CB 3.33Å; T196-R199 PolarHBondContact O-N 2.83Å; T196-M200 HydrophobicContact CG2-CE 4.19Å; T196-M200 HydrophobicContact CG2-CG 4.36Å; T196-M200 VanDerWaalsContact O-CG 3.31Å; T196-M200 WeakPolarHBondContact O-CG 3.22Å; T196-M200 PolarHBondContact O-N 3.25Å; T196-L413 HydrophobicContact CG2-CD1 4.21Å; T196-W416 HydrophobicContact CG2-CB 3.54Å
197	A	93.8	Very high	91.4	Very high	7 Å²	7	24.3 Å²	24.3	6%	0.058	13%	0.131	C	C	.	.	H	α-helix	trans	-63.8	-42.3	176.4	0	0	0	0	0	112.9	D193 S194 M200 T201 I357 Q361 L413	D193-A197 PolarHBondContact O-N 3.33Å; S194-A197 WeakPolarHBondContact O-CB 3.36Å; S194-A197 PolarHBondContact O-N 3.16Å; S194-A197 VanDerWaalsContact O-N 3.09Å; A197-M200 PolarHBondContact O-N 2.9Å; A197-T201 WeakPolarHBondContact O-CB 3.42Å; A197-T201 PolarHBondContact O-N 3.34Å; A197-T201 PolarHBondContact O-OG1 3.29Å; A197-I357 HydrophobicContact CB-CG2 4.17Å; A197-I357 WeakPolarHBondContact O-CG2 3.27Å; A197-Q361 HydrophobicContact CB-CB 3.79Å; A197-Q361 HydrophobicContact CB-CG 3.67Å; A197-L413 HydrophobicContact CB-CD1 4.03Å
198	Y	94.8	Very high	91.7	Very high	95 Å²	95	23.6 Å²	23.6	37%	0.373	13%	0.126	S	C	.	.	H	α-helix	trans	-61	-46.1	173	-82.4	-95.2	0	0	0	110.8	K46 A50 S194 A195 T201 V202	K46-Y198 HydrophobicContact CB-CD2 4.27Å; K46-Y198 HydrophobicContact CB-CG 4.36Å; K46-Y198 HydrophobicContact CD-CD2 4.36Å; K46-Y198 HydrophobicContact CD-CE2 4.27Å; A50-Y198 VanDerWaalsContact CB-C 3.41Å; A50-Y198 WeakPolarHBondContact CB-O 3.22Å; S194-Y198 VanDerWaalsContact O-CD2 3.29Å; S194-Y198 WeakPolarHBondContact O-CD2 3.43Å; S194-Y198 PolarHBondContact O-N 3.44Å; S194-Y198 VanDerWaalsContact O-N 3.08Å; A195-Y198 PolarHBondContact O-N 3.14Å; Y198-T201 WeakPolarHBondContact O-CB 3.25Å; Y198-T201 PolarHBondContact O-N 3.12Å; Y198-V202 PolarHBondContact O-N 2.77Å
199	R	94.7	Very high	91.9	Very high	0 Å²	0	25.4 Å²	25.4	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-55.9	-53	176.3	174.2	173.7	79	91.5	-11.2	112.1	Y49 Y178 A195 T196 T201 V202 E203	Y49-R199 HydrophobicContact CE1-CB 4.01Å; Y49-R199 WeakPolarHBondContact OH-CD 3.31Å; Y178-R199 VanDerWaalsContact CE1-CD 3.44Å; Y178-R199 HydrophobicContact CE1-CG 4.11Å; Y178-R199 WeakPolarHBondContact OH-CD 3.34Å; Y178-R199 VanDerWaalsContact OH-CG 3.23Å; Y178-R199 WeakPolarHBondContact OH-CG 3.33Å; A195-R199 WeakPolarHBondContact O-CB 3.33Å; A195-R199 PolarHBondContact O-N 3.32Å; T196-R199 WeakPolarHBondContact O-CB 3.33Å; T196-R199 PolarHBondContact O-N 2.83Å; R199-T201 VanDerWaalsContact C-N 3.26Å; R199-T201 PolarHBondContact O-N 2.7Å; R199-V202 PolarHBondContact O-N 3.12Å; R199-V202 VanDerWaalsContact O-N 3.15Å; R199-E203 WeakPolarHBondContact CD-OE1 3.29Å; R199-E203 HydrophobicContact CG-CG 4.3Å; R199-E203 WeakPolarHBondContact CG-OE1 3.1Å; R199-E203 IonicContact CZ-OE1 3.53Å; R199-E203 IonicContact NE-OE1 3.71Å; R199-E203 IonicContact NH1-OE1 3.81Å; R199-E203 PolarHBondContact NH1-OE1 3.05Å; R199-E203 IonicContact NH1-OE2 2.85Å; R199-E203 PolarHBondContact NH1-OE2 3.06Å; R199-E203 WeakPolarHBondContact O-CB 3.32Å; R199-E203 WeakPolarHBondContact O-CG 3.35Å; R199-E203 PolarHBondContact O-N 3.12Å
200	M	94.1	Very high	91.9	Very high	2 Å²	2	24.5 Å²	24.5	1%	0.01	13%	0.133	C	C	.	.	H	α-helix	trans	-58.8	-39.4	179.5	-69.2	-62.6	144.5	0	0	112.3	T196 A197 E203 V204 I357 F412 L413 W416	T196-M200 HydrophobicContact CG2-CE 4.19Å; T196-M200 HydrophobicContact CG2-CG 4.36Å; T196-M200 VanDerWaalsContact O-CG 3.31Å; T196-M200 WeakPolarHBondContact O-CG 3.22Å; T196-M200 PolarHBondContact O-N 3.25Å; A197-M200 PolarHBondContact O-N 2.9Å; M200-E203 PolarHBondContact O-N 2.91Å; M200-V204 WeakPolarHBondContact O-CG2 3.27Å; M200-V204 PolarHBondContact O-N 3.35Å; M200-I357 HydrophobicContact CB-CD1 4.02Å; M200-I357 HydrophobicContact CB-CG2 4.42Å; M200-F412 HydrophobicContact SD-CB 4.41Å; M200-L413 HydrophobicContact CB-CD1 4.28Å; M200-L413 HydrophobicContact CG-CD1 3.84Å; M200-W416 HydrophobicContact CE-CB 3.77Å; M200-W416 HydrophobicContact CE-CD2 4.02Å; M200-W416 HydrophobicContact CE-CG 3.35Å
201	T	94.6	Very high	91.6	Very high	32 Å²	32	22.7 Å²	22.7	20%	0.196	12%	0.121	C	C	.	.	H	α-helix	trans	-62.1	-46.2	178.2	-54.5	0	0	0	0	110.7	A197 Y198 R199 L205 T354 I357	A197-T201 WeakPolarHBondContact O-CB 3.42Å; A197-T201 PolarHBondContact O-N 3.34Å; A197-T201 PolarHBondContact O-OG1 3.29Å; Y198-T201 WeakPolarHBondContact O-CB 3.25Å; Y198-T201 PolarHBondContact O-N 3.12Å; R199-T201 VanDerWaalsContact C-N 3.26Å; R199-T201 PolarHBondContact O-N 2.7Å; T201-L205 HydrophobicContact CG2-CD1 4.38Å; T201-L205 WeakPolarHBondContact O-CG 3.12Å; T201-L205 PolarHBondContact O-N 3.33Å; T201-L205 VanDerWaalsContact O-N 3.11Å; T201-T354 HydrophobicContact CG2-CG2 3.71Å; T201-I357 WeakPolarHBondContact OG1-CG2 3.23Å
202	V	95.3	Very high	91.3	Very high	20 Å²	20	23.6 Å²	23.6	12%	0.121	13%	0.133	C	C	.	.	H	α-helix	trans	-68.6	-36.5	178.3	172.4	0	0	0	0	111.8	A50 L51 A54 Y198 R199 L205 G206	A50-V202 HydrophobicContact CB-CB 4.17Å; A50-V202 HydrophobicContact CB-CG2 3.68Å; A50-V202 VanDerWaalsContact O-CG1 3.29Å; A50-V202 WeakPolarHBondContact O-CG1 3.28Å; L51-V202 HydrophobicContact CD2-CG1 4.42Å; A54-V202 HydrophobicContact CB-CG1 3.88Å; Y198-V202 PolarHBondContact O-N 2.77Å; R199-V202 PolarHBondContact O-N 3.12Å; R199-V202 VanDerWaalsContact O-N 3.15Å; V202-L205 PolarHBondContact O-N 3.47Å; V202-G206 PolarHBondContact O-N 3.21Å
203	E	94	Very high	91	Very high	7 Å²	7	24.5 Å²	24.5	3%	0.033	14%	0.138	C	C	.	.	H	α-helix	trans	-61.8	-48.6	176.2	-82.7	-175.5	-155.4	0	0	112.2	Q57 R199 M200 L205 G206 T207	Q57-E203 WeakPolarHBondContact CB-O 3.37Å; Q57-E203 HydrophobicContact CG-CB 3.61Å; Q57-E203 HydrophobicContact CG-CG 3.65Å; Q57-E203 PolarHBondContact NE2-OE2 3.37Å; Q57-E203 VanDerWaalsContact NE2-OE2 3.13Å; R199-E203 WeakPolarHBondContact CD-OE1 3.29Å; R199-E203 HydrophobicContact CG-CG 4.3Å; R199-E203 WeakPolarHBondContact CG-OE1 3.1Å; R199-E203 IonicContact CZ-OE1 3.53Å; R199-E203 IonicContact NE-OE1 3.71Å; R199-E203 IonicContact NH1-OE1 3.81Å; R199-E203 PolarHBondContact NH1-OE1 3.05Å; R199-E203 IonicContact NH1-OE2 2.85Å; R199-E203 PolarHBondContact NH1-OE2 3.06Å; R199-E203 WeakPolarHBondContact O-CB 3.32Å; R199-E203 WeakPolarHBondContact O-CG 3.35Å; R199-E203 PolarHBondContact O-N 3.12Å; M200-E203 PolarHBondContact O-N 2.91Å; E203-L205 VanDerWaalsContact C-N 3.33Å; E203-L205 PolarHBondContact O-N 3.35Å; E203-G206 WeakPolarHBondContact O-CA 3.19Å; E203-G206 PolarHBondContact O-N 3.39Å; E203-G206 VanDerWaalsContact O-N 3.07Å; E203-T207 PolarHBondContact O-N 3.32Å; E203-T207 PolarHBondContact O-OG1 3.09Å
204	V	91.9	Very high	90.3	Very high	12 Å²	12	23.9 Å²	23.9	7%	0.073	14%	0.135	C	C	.	.	H	α-helix	trans	-63.5	-40	176.6	178.3	0	0	0	0	111.2	M200 G206 T207 V208 M350 T354 I357	M200-V204 WeakPolarHBondContact O-CG2 3.27Å; M200-V204 PolarHBondContact O-N 3.35Å; V204-G206 VanDerWaalsContact C-N 3.29Å; V204-G206 PolarHBondContact O-N 3.48Å; V204-T207 WeakPolarHBondContact O-CB 3.31Å; V204-T207 PolarHBondContact O-N 3.29Å; V204-V208 PolarHBondContact O-N 3.14Å; V204-M350 HydrophobicContact CG1-CB 4.25Å; V204-M350 WeakPolarHBondContact CG1-O 3.36Å; V204-M350 HydrophobicContact CG1-SD 4.33Å; V204-T354 WeakPolarHBondContact CG1-OG1 2.99Å; V204-I357 HydrophobicContact CG2-CD1 4.13Å
205	L	92.5	Very high	89.5	Confident	78 Å²	78	23.6 Å²	23.6	41%	0.408	14%	0.135	S	C	.	.	H	α-helix	trans	-63.6	-36	172.7	-73.8	172.1	0	0	0	112.2	T201 V202 E203 V208 L209 T354	T201-L205 HydrophobicContact CG2-CD1 4.38Å; T201-L205 WeakPolarHBondContact O-CG 3.12Å; T201-L205 PolarHBondContact O-N 3.33Å; T201-L205 VanDerWaalsContact O-N 3.11Å; V202-L205 PolarHBondContact O-N 3.47Å; E203-L205 VanDerWaalsContact C-N 3.33Å; E203-L205 PolarHBondContact O-N 3.35Å; L205-V208 PolarHBondContact O-N 3.46Å; L205-L209 WeakPolarHBondContact O-CB 3.25Å; L205-L209 PolarHBondContact O-N 3.24Å; L205-T354 HydrophobicContact CD1-CG2 4.21Å; L205-T354 HydrophobicContact CD2-CG2 3.94Å; L205-T354 HydrophobicContact CG-CG2 3.82Å
206	G	92.4	Very high	88.6	Confident	4 Å²	4	30.8 Å²	30.8	4%	0.041	17%	0.168	C	C	.	.	H	α-helix	trans	-62.2	-42.8	174.4	0	0	0	0	0	112.2	V58 V202 E203 V204 V208 L209 G210	V58-G206 VanDerWaalsContact CG2-O 3.28Å; V58-G206 WeakPolarHBondContact CG2-O 3.48Å; V202-G206 PolarHBondContact O-N 3.21Å; E203-G206 WeakPolarHBondContact O-CA 3.19Å; E203-G206 PolarHBondContact O-N 3.39Å; E203-G206 VanDerWaalsContact O-N 3.07Å; V204-G206 VanDerWaalsContact C-N 3.29Å; V204-G206 PolarHBondContact O-N 3.48Å; G206-V208 PolarHBondContact O-N 3.42Å; G206-L209 PolarHBondContact O-N 3.5Å; G206-G210 PolarHBondContact O-N 3.38Å
207	T	88.7	Confident	87.4	Confident	26 Å²	26	33.3 Å²	33.3	16%	0.16	18%	0.181	C	C	.	.	H	α-helix	trans	-57.8	-46.6	173.1	-64.4	0	0	0	0	112	C61 E203 V204 T211	C61-T207 HydrophobicContact CB-CG2 4.49Å; C61-T207 WeakPolarHBondContact SG-CG2 3Å; C61-T207 PolarHBondContact SG-OG1 3.35Å; C61-T207 VanDerWaalsContact SG-OG1 3.37Å; E203-T207 PolarHBondContact O-N 3.32Å; E203-T207 PolarHBondContact O-OG1 3.09Å; V204-T207 WeakPolarHBondContact O-CB 3.31Å; V204-T207 PolarHBondContact O-N 3.29Å; T207-T211 WeakPolarHBondContact O-CB 3.32Å; T207-T211 PolarHBondContact O-N 3.08Å; T207-T211 PolarHBondContact O-OG1 2.87Å
208	V	87.9	Confident	85.8	Confident	26 Å²	26	34.4 Å²	34.4	16%	0.158	19%	0.187	C	C	.	.	H	α-helix	trans	-62.5	-46.2	176.8	173.6	0	0	0	0	110.7	V204 L205 G206 T211 A212 L347 M350	V204-V208 PolarHBondContact O-N 3.14Å; L205-V208 PolarHBondContact O-N 3.46Å; G206-V208 PolarHBondContact O-N 3.42Å; V208-T211 PolarHBondContact O-N 3.23Å; V208-A212 VanDerWaalsContact O-CB 3.23Å; V208-A212 WeakPolarHBondContact O-CB 3.34Å; V208-A212 PolarHBondContact O-N 3.36Å; V208-L347 HydrophobicContact CG1-CD2 3.78Å; V208-M350 HydrophobicContact CG2-CB 3.58Å; V208-M350 HydrophobicContact CG2-CG 4.35Å
209	L	89.9	Confident	83.9	Confident	77 Å²	77	32.2 Å²	32.2	40%	0.403	19%	0.193	S	C	.	.	H	α-helix	trans	-63.5	-45.3	-179.4	-177.1	62	0	0	0	112.1	L205 G206 A212 I213 I265	L205-L209 WeakPolarHBondContact O-CB 3.25Å; L205-L209 PolarHBondContact O-N 3.24Å; G206-L209 PolarHBondContact O-N 3.5Å; L209-A212 PolarHBondContact O-N 3.45Å; L209-I213 HydrophobicContact CD1-CD1 3.87Å; L209-I213 HydrophobicContact CD1-CG1 4.14Å; L209-I213 HydrophobicContact CG-CD1 3.76Å; L209-I213 HydrophobicContact CG-CG1 4.42Å; L209-I213 WeakPolarHBondContact O-CB 3.47Å; L209-I213 WeakPolarHBondContact O-CG1 3.36Å; L209-I213 PolarHBondContact O-N 3.36Å; L209-I265 HydrophobicContact CD2-CD1 4.18Å
210	G	86.8	Confident	81.8	Confident	0 Å²	0	40.1 Å²	40.1	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-62.2	-44.5	177.9	0	0	0	0	0	112.3	G206 Q214	G206-G210 PolarHBondContact O-N 3.38Å; G210-Q214 WeakPolarHBondContact O-CB 3.43Å; G210-Q214 PolarHBondContact O-N 3.39Å
211	T	80.9	Confident	79.5	Confident	33 Å²	33	42.5 Å²	42.5	20%	0.202	25%	0.25	C	C	.	.	H	α-helix	trans	-66.5	-38.9	177	-50.2	0	0	0	0	111.7	F65 T207 V208 G215	F65-T211 HydrophobicContact CD2-CG2 4.47Å; T207-T211 WeakPolarHBondContact O-CB 3.32Å; T207-T211 PolarHBondContact O-N 3.08Å; T207-T211 PolarHBondContact O-OG1 2.87Å; V208-T211 PolarHBondContact O-N 3.23Å; T211-G215 VanDerWaalsContact O-CA 3.26Å; T211-G215 WeakPolarHBondContact O-CA 3.33Å; T211-G215 PolarHBondContact O-N 2.76Å
212	A	84.1	Confident	77.3	Confident	42 Å²	42	47.7 Å²	47.7	35%	0.347	28%	0.276	S	S	.	.	H	α-helix	trans	-67.8	-44.9	177.5	0	0	0	0	0	112.2	V208 L209 Q216	V208-A212 VanDerWaalsContact O-CB 3.23Å; V208-A212 WeakPolarHBondContact O-CB 3.34Å; V208-A212 PolarHBondContact O-N 3.36Å; L209-A212 PolarHBondContact O-N 3.45Å; A212-Q216 WeakPolarHBondContact O-CB 3.41Å; A212-Q216 VanDerWaalsContact O-CG 3.23Å; A212-Q216 WeakPolarHBondContact O-CG 3.4Å; A212-Q216 PolarHBondContact O-N 2.89Å
213	I	85.2	Confident	75	Confident	22 Å²	22	51.9 Å²	51.9	11%	0.113	30%	0.302	C	S	.	.	H	α-helix	trans	-59.8	-55	177.7	-69.7	166	0	0	0	109.4	L209 I217 A258 V261 I262 I265	L209-I213 HydrophobicContact CD1-CD1 3.87Å; L209-I213 HydrophobicContact CD1-CG1 4.14Å; L209-I213 HydrophobicContact CG-CD1 3.76Å; L209-I213 HydrophobicContact CG-CG1 4.42Å; L209-I213 WeakPolarHBondContact O-CB 3.47Å; L209-I213 WeakPolarHBondContact O-CG1 3.36Å; L209-I213 PolarHBondContact O-N 3.36Å; I213-I217 HydrophobicContact CG2-CD1 3.85Å; I213-I217 VanDerWaalsContact O-CB 3.28Å; I213-I217 WeakPolarHBondContact O-CB 3.3Å; I213-I217 WeakPolarHBondContact O-CD1 3.39Å; I213-I217 WeakPolarHBondContact O-CG1 3.49Å; I213-I217 PolarHBondContact O-N 2.87Å; I213-A258 HydrophobicContact CG2-CB 4.22Å; I213-V261 HydrophobicContact CD1-CG1 4.22Å; I213-I262 HydrophobicContact CD1-CG1 4.44Å; I213-I262 HydrophobicContact CG2-CD1 4.37Å; I213-I262 HydrophobicContact CG2-CG1 4.22Å; I213-I265 HydrophobicContact CD1-CD1 3.68Å
214	Q	77.2	Confident	73.1	Confident	0 Å²	0	57.2 Å²	57.2	0%	0	34%	0.337	C	S	.	.	H	α-helix	trans	-70.8	-39.7	-175.7	-155.2	71.9	40.1	0	0	111.5	F66 G210 V218	F66-Q214 HydrophobicContact CB-CG 3.87Å; F66-Q214 HydrophobicContact CD1-CG 3.9Å; F66-Q214 HydrophobicContact CD2-CB 3.63Å; F66-Q214 HydrophobicContact CD2-CG 3.36Å; F66-Q214 HydrophobicContact CE1-CB 4.41Å; F66-Q214 HydrophobicContact CE1-CG 4.26Å; F66-Q214 HydrophobicContact CE2-CB 3.52Å; F66-Q214 HydrophobicContact CE2-CG 3.79Å; F66-Q214 HydrophobicContact CG-CB 4.15Å; F66-Q214 HydrophobicContact CG-CG 3.43Å; F66-Q214 VanDerWaalsContact CG-CG 3.43Å; F66-Q214 HydrophobicContact CZ-CB 3.94Å; F66-Q214 HydrophobicContact CZ-CG 4.21Å; G210-Q214 WeakPolarHBondContact O-CB 3.43Å; G210-Q214 PolarHBondContact O-N 3.39Å; Q214-V218 HydrophobicContact CG-CG2 4.41Å; Q214-V218 WeakPolarHBondContact O-CB 3.49Å; Q214-V218 WeakPolarHBondContact O-CG2 3.26Å; Q214-V218 PolarHBondContact O-N 3.27Å
215	G	73.6	Confident	71.4	Confident	12 Å²	12	59.1 Å²	59.1	12%	0.124	35%	0.351	C	S	.	.	H	α-helix	trans	-69.6	-40.5	-178.7	0	0	0	0	0	114.3	T211 I217 G219	T211-G215 VanDerWaalsContact O-CA 3.26Å; T211-G215 WeakPolarHBondContact O-CA 3.33Å; T211-G215 PolarHBondContact O-N 2.76Å; G215-I217 VanDerWaalsContact C-N 3.35Å; G215-G219 WeakPolarHBondContact O-CA 3.43Å; G215-G219 PolarHBondContact O-N 3.36Å
216	Q	74.8	Confident	69.5	Low	150 Å²	150	62 Å²	62	70%	0.701	36%	0.36	S	S	*	.	H	α-helix	trans	-72.5	-31.4	176.8	-69.7	-69.8	-51	0	0	112.2	A212	A212-Q216 WeakPolarHBondContact O-CB 3.41Å; A212-Q216 VanDerWaalsContact O-CG 3.23Å; A212-Q216 WeakPolarHBondContact O-CG 3.4Å; A212-Q216 PolarHBondContact O-N 2.89Å
217	I	68.1	Low	67.4	Low	55 Å²	55	69.3 Å²	69.3	28%	0.282	39%	0.393	S	S	.	.	H	α-helix	trans	-79.9	-30.2	-178.8	-65.5	171.8	0	0	0	111.5	I213 G215 A254 A258	I213-I217 HydrophobicContact CG2-CD1 3.85Å; I213-I217 VanDerWaalsContact O-CB 3.28Å; I213-I217 WeakPolarHBondContact O-CB 3.3Å; I213-I217 WeakPolarHBondContact O-CD1 3.39Å; I213-I217 WeakPolarHBondContact O-CG1 3.49Å; I213-I217 PolarHBondContact O-N 2.87Å; G215-I217 VanDerWaalsContact C-N 3.35Å; I217-A254 HydrophobicContact CG2-CB 3.65Å; I217-A254 VanDerWaalsContact CG2-O 3.28Å; I217-A254 WeakPolarHBondContact CG2-O 3.35Å; I217-A258 HydrophobicContact CB-CB 4.42Å; I217-A258 HydrophobicContact CD1-CB 3.73Å; I217-A258 HydrophobicContact CG2-CB 4.18Å
218	V	61	Low	65.1	Low	30 Å²	30	74.3 Å²	74.3	18%	0.182	42%	0.419	C	S	.	.	H	α-helix	trans	-104.8	-33.4	-176.4	177.5	0	0	0	0	113.1	Q214 Q220 A221 Y255	Q214-V218 HydrophobicContact CG-CG2 4.41Å; Q214-V218 WeakPolarHBondContact O-CB 3.49Å; Q214-V218 WeakPolarHBondContact O-CG2 3.26Å; Q214-V218 PolarHBondContact O-N 3.27Å; V218-Q220 PolarHBondContact O-N 3.14Å; V218-A221 PolarHBondContact O-N 3.47Å; V218-Y255 HydrophobicContact CB-CE2 4.38Å; V218-Y255 HydrophobicContact CG1-CE1 4.4Å; V218-Y255 HydrophobicContact CG1-CE2 3.72Å; V218-Y255 VanDerWaalsContact CG1-OH 3.26Å; V218-Y255 WeakPolarHBondContact CG1-OH 3.5Å; V218-Y255 HydrophobicContact CG2-CD1 3.99Å; V218-Y255 HydrophobicContact CG2-CD2 4.04Å; V218-Y255 HydrophobicContact CG2-CE1 3.63Å; V218-Y255 HydrophobicContact CG2-CE2 3.68Å; V218-Y255 HydrophobicContact CG2-CG 4.19Å; V218-Y255 VanDerWaalsContact CG2-CZ 3.5Å
219	G	55	Low	63.2	Low	48 Å²	48	81.1 Å²	81.1	50%	0.495	45%	0.454	S	S	.	.	T	Hydrogen-bonded Turn	trans	-71.3	11.4	-170.5	0	0	0	0	0	116.1	G215 A221	G215-G219 WeakPolarHBondContact O-CA 3.43Å; G215-G219 PolarHBondContact O-N 3.36Å; G219-A221 PolarHBondContact O-N 3.19Å
220	Q	49.7	Very low	61.1	Low	167 Å²	167	85.5 Å²	85.5	78%	0.78	48%	0.478	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.4	-0.7	168.7	-67.5	-167.4	-21.3	0	0	113.1	V218	V218-Q220 PolarHBondContact O-N 3.14Å
221	A	46.2	Very low	58.7	Low	52 Å²	52	88.9 Å²	88.9	43%	0.43	51%	0.513	S	S	.	.			trans	-99.2	85.5	173	0	0	0	0	0	110.8	V218 G219 T223	V218-A221 PolarHBondContact O-N 3.47Å; G219-A221 PolarHBondContact O-N 3.19Å; A221-T223 PolarHBondContact O-N 3.09Å; A221-T223 VanDerWaalsContact O-N 3.09Å
222	D	47.6	Very low	56.9	Low	140 Å²	140	92.5 Å²	92.5	75%	0.749	54%	0.539	S	S	*	.			trans	-60.4	111	164	-83.7	-37.3	0	0	0	108.4	P224	D222-P224 VanDerWaalsContact O-CD 3.25Å; D222-P224 WeakPolarHBondContact O-CD 3.31Å
223	T	48.4	Very low	54.9	Low	108 Å²	108	96.5 Å²	96.5	66%	0.663	56%	0.559	S	S	*	*			trans	-88.8	109.7	172.7	45.8	0	0	0	0	108.8	A221	A221-T223 PolarHBondContact O-N 3.09Å; A221-T223 VanDerWaalsContact O-N 3.09Å
224	P	52.9	Low	52.7	Low	119 Å²	119	102.2 Å²	102.2	77%	0.773	60%	0.595	S	S	*	*			trans	-65.3	143.5	178.5	25.5	-32.2	0	0	0	110.6	D222	D222-P224 VanDerWaalsContact O-CD 3.25Å; D222-P224 WeakPolarHBondContact O-CD 3.31Å
225	C	56.2	Low	50.6	Low	53 Å²	53	105.8 Å²	105.8	36%	0.358	62%	0.624	S	S	.	*			trans	-69.5	153.7	174.4	64.5	0	0	0	0	111.1	Q227 C473	C225-Q227 PolarHBondContact O-N 3.32Å; C225-C473 HydrophobicContact CB-CB 4.11Å; C225-C473 WeakPolarHBondContact CB-SG 3.43Å; C225-C473 WeakPolarHBondContact SG-CB 3.48Å; C225-C473 CovalentContact SG-SG 2.05Å; C225-C473 PolarHBondContact SG-SG 2.92Å
226	F	52	Low	49.1	Very low	137 Å²	137	111.5 Å²	111.5	60%	0.601	66%	0.663	S	S	*	*	B	Isolated β-bridge	trans	-73.8	114.2	172.8	-70.4	-69.9	0	0	0	109.2	R471 C473	F226-R471 HydrophobicContact CD2-CB 3.88Å; F226-R471 HydrophobicContact CE2-CB 4.3Å; F226-R471 PolarHBondContact N-O 2.84Å; F226-C473 VanDerWaalsContact C-SG 3.56Å; F226-C473 PolarHBondContact O-SG 3.11Å
227	Q	49.3	Very low	47	Very low	159 Å²	159	112.4 Å²	112.4	74%	0.743	67%	0.667	S	S	*	*			trans	-77	126.2	165.5	-84.3	-180	-37.2	0	0	108.9	C225 L229	C225-Q227 PolarHBondContact O-N 3.32Å; Q227-L229 PolarHBondContact O-N 3.07Å
228	D	40.4	Very low	45.6	Very low	130 Å²	130	115.3 Å²	115.3	70%	0.695	69%	0.692	S	S	*	*			trans	-63.8	104.7	166.1	-72.1	-38.6	0	0	0	108.6	N230	D228-N230 VanDerWaalsContact C-N 3.28Å; D228-N230 PolarHBondContact O-N 3.49Å
229	L	48.1	Very low	44.2	Very low	169 Å²	169	117.8 Å²	117.8	89%	0.885	72%	0.715	S	S	*	*			trans	-69.4	87.5	170.3	-87.5	109.2	0	0	0	109.2	Q227	Q227-L229 PolarHBondContact O-N 3.07Å
230	N	44.9	Very low	43.1	Very low	170 Å²	170	123.7 Å²	123.7	91%	0.909	74%	0.735	S	S	*	*			trans	-138.9	38	164.6	-116.8	0.9	0	0	0	112.7	D228	D228-N230 VanDerWaalsContact C-N 3.28Å; D228-N230 PolarHBondContact O-N 3.49Å
231	G	37.9	Very low	42.4	Very low	71 Å²	71	122.5 Å²	122.5	73%	0.732	73%	0.73	S	S	*	*	S	Bend	trans	-135	109.6	169	0	0	0	0	0	109.5
232	S	41.6	Very low	41.6	Very low	108 Å²	108	126.8 Å²	126.8	76%	0.755	75%	0.751	S	S	*	*			trans	-51.5	141.3	177.5	35	0	0	0	0	114.6
233	T	42	Very low	41.2	Very low	127 Å²	127	127 Å²	127	78%	0.779	75%	0.747	S	S	*	*			trans	73.1	119.4	148.3	51.8	0	0	0	0	120.8
234	V	39.3	Very low	40.7	Very low	142 Å²	142	124.9 Å²	124.9	86%	0.861	75%	0.747	S	S	*	*			trans	76.9	101.1	141.6	-175	0	0	0	0	117.2
235	A	33	Very low	40.3	Very low	74 Å²	74	125.6 Å²	125.6	61%	0.612	75%	0.749	S	S	*	*				-177.8	110.8	106.3	0	0	0	0	0	110.3	Q237	A235-Q237 PolarHBondContact O-N 3.47Å; A235-Q237 VanDerWaalsContact O-N 3.08Å
236	S	42.5	Very low	40.2	Very low	133 Å²	133	126.1 Å²	126.1	93%	0.93	75%	0.75	S	S	*	*			trans	-60.5	104.6	148.7	-70.2	0	0	0	0	107.4
237	Q	31.8	Very low	40.8	Very low	169 Å²	169	122.5 Å²	122.5	79%	0.79	74%	0.742	S	S	*	*			trans	-124.1	111.4	158.1	-82.1	-174.3	-8.8	0	0	108.6	A235 A239	A235-Q237 PolarHBondContact O-N 3.47Å; A235-Q237 VanDerWaalsContact O-N 3.08Å; Q237-A239 PolarHBondContact O-N 2.95Å
238	S	38.3	Very low	41.7	Very low	116 Å²	116	119.6 Å²	119.6	81%	0.811	73%	0.728	S	S	*	*			trans	-28.1	98.4	160.4	49.6	0	0	0	0	113.5
239	A	30.3	Very low	43.2	Very low	81 Å²	81	121.3 Å²	121.3	67%	0.669	73%	0.725	S	S	*	*			trans	-91.2	101.5	149.3	0	0	0	0	0	106.7	Q237 H241	Q237-A239 PolarHBondContact O-N 2.95Å; A239-H241 PolarHBondContact O-N 3.06Å
240	N	33	Very low	44.6	Very low	172 Å²	172	118.7 Å²	118.7	92%	0.92	71%	0.708	S	S	*	*			trans	-65.6	66.8	156.9	-89.4	-12.9	0	0	0	108.5
241	H	33.7	Very low	46.2	Very low	142 Å²	142	112.2 Å²	112.2	66%	0.657	68%	0.675	S	S	*	*			trans	-95.6	115.1	151.6	-98.3	-81.3	0	0	0	105.4	A239 H243	A239-H241 PolarHBondContact O-N 3.06Å; H241-H243 PolarHBondContact O-N 3.18Å
242	T	30.8	Very low	48.2	Very low	143 Å²	143	111 Å²	111	88%	0.877	65%	0.65	S	S	*	*			trans	-58.9	75.3	153.4	38.5	0	0	0	0	107.8	G244	T242-G244 VanDerWaalsContact C-N 3.29Å; T242-G244 PolarHBondContact O-N 3.26Å
243	H	39.3	Very low	50.2	Low	145 Å²	145	112.1 Å²	112.1	67%	0.671	64%	0.641	S	S	*	*			trans	-65	99.4	159.6	-97.1	-91.5	0	0	0	104.7	H241 T245	H241-H243 PolarHBondContact O-N 3.18Å; H243-T245 VanDerWaalsContact C-N 3.33Å; H243-T245 PolarHBondContact O-N 2.75Å
244	G	37.9	Very low	52.3	Low	63 Å²	63	107 Å²	107	65%	0.649	61%	0.613	S	S	*	*			trans	-58.3	106	163.9	0	0	0	0	0	106.4	T242 T246	T242-G244 VanDerWaalsContact C-N 3.29Å; T242-G244 PolarHBondContact O-N 3.26Å; G244-T246 PolarHBondContact O-N 3Å
245	T	44.2	Very low	54.6	Low	133 Å²	133	100.4 Å²	100.4	82%	0.816	57%	0.572	S	S	*	*			trans	-61.3	86.7	159.3	46.7	0	0	0	0	105.7	H243 S247	H243-T245 VanDerWaalsContact C-N 3.33Å; H243-T245 PolarHBondContact O-N 2.75Å; T245-S247 PolarHBondContact O-N 2.99Å
246	T	54.3	Low	57.3	Low	64 Å²	64	99.4 Å²	99.4	39%	0.393	56%	0.556	S	S	.	*			trans	-53.2	118.5	172.5	41.2	0	0	0	0	106.7	G244	G244-T246 PolarHBondContact O-N 3Å
247	S	64.3	Low	59.6	Low	62 Å²	62	98.6 Å²	98.6	43%	0.434	54%	0.541	S	S	.	.			trans	-61.3	142	-178	-179.8	0	0	0	0	108.8	T245 R249 E250 T251	T245-S247 PolarHBondContact O-N 2.99Å; S247-R249 PolarHBondContact O-N 3.04Å; S247-E250 PolarHBondContact N-OE2 3.21Å; S247-E250 WeakPolarHBondContact O-CA 3.49Å; S247-E250 WeakPolarHBondContact O-CB 3.36Å; S247-E250 PolarHBondContact O-N 3.49Å; S247-T251 PolarHBondContact O-N 2.89Å
248	H	67.4	Low	62.4	Low	97 Å²	97	90.5 Å²	90.5	45%	0.449	50%	0.503	S	S	.	.	H	α-helix	trans	-49.4	-28.5	172.5	-78	-92.8	0	0	0	112.5	D78 T251 Q252	D78-H248 IonicContact OD2-CE1 3.01Å; D78-H248 IonicContact OD2-NE2 3.22Å; H248-T251 PolarHBondContact O-OG1 3.01Å; H248-Q252 WeakPolarHBondContact O-CB 3.48Å; H248-Q252 WeakPolarHBondContact O-CG 3.48Å; H248-Q252 PolarHBondContact O-N 3.47Å; H248-Q252 VanDerWaalsContact O-N 3.1Å
249	R	72.3	Confident	64.9	Low	167 Å²	167	85 Å²	85	63%	0.63	46%	0.464	S	S	*	.	H	α-helix	trans	-75.9	-26.9	176.9	-165.1	163.2	175.8	87.4	-5	113.5	S247 K253	S247-R249 PolarHBondContact O-N 3.04Å; R249-K253 VanDerWaalsContact O-CG 3.25Å; R249-K253 WeakPolarHBondContact O-CG 3.47Å; R249-K253 PolarHBondContact O-N 3.25Å
250	E	78.5	Confident	67.9	Low	113 Å²	113	82.1 Å²	82.1	53%	0.528	44%	0.443	S	S	.	.	H	α-helix	trans	-75.2	-42.1	173.7	-67.9	173.7	158.1	0	0	110.8	S247 K253 A254	S247-E250 PolarHBondContact N-OE2 3.21Å; S247-E250 WeakPolarHBondContact O-CA 3.49Å; S247-E250 WeakPolarHBondContact O-CB 3.36Å; S247-E250 PolarHBondContact O-N 3.49Å; E250-K253 PolarHBondContact O-N 3.21Å; E250-A254 WeakPolarHBondContact O-CB 3.48Å; E250-A254 PolarHBondContact O-N 3.17Å
251	T	77.4	Confident	70.8	Confident	34 Å²	34	76.9 Å²	76.9	21%	0.209	42%	0.417	C	S	.	.	H	α-helix	trans	-63.9	-43.4	175.2	58.4	0	0	0	0	111.3	S247 H248 K253 A254 Y255	S247-T251 PolarHBondContact O-N 2.89Å; H248-T251 PolarHBondContact O-OG1 3.01Å; T251-K253 VanDerWaalsContact C-N 3.34Å; T251-K253 PolarHBondContact O-N 3.2Å; T251-A254 WeakPolarHBondContact O-CB 3.31Å; T251-A254 PolarHBondContact O-N 3.18Å; T251-A254 VanDerWaalsContact O-N 3.13Å; T251-Y255 VanDerWaalsContact O-CD2 3.3Å; T251-Y255 WeakPolarHBondContact O-CD2 3.38Å; T251-Y255 PolarHBondContact O-N 3.08Å
252	Q	80.2	Confident	73.7	Confident	46 Å²	46	70.1 Å²	70.1	22%	0.215	39%	0.386	C	S	.	.	H	α-helix	trans	-54.5	-46.5	172.1	-77	173.3	-3.8	0	0	112.7	V74 V149 H248 A254 Y255 L256	V74-Q252 HydrophobicContact CG1-CB 4.3Å; V74-Q252 HydrophobicContact CG1-CG 3.26Å; V74-Q252 PolarHBondContact O-NE2 3.17Å; V149-Q252 HydrophobicContact CG2-CG 4.11Å; H248-Q252 WeakPolarHBondContact O-CB 3.48Å; H248-Q252 WeakPolarHBondContact O-CG 3.48Å; H248-Q252 PolarHBondContact O-N 3.47Å; H248-Q252 VanDerWaalsContact O-N 3.1Å; Q252-A254 VanDerWaalsContact C-N 3.33Å; Q252-A254 PolarHBondContact O-N 3.47Å; Q252-Y255 PolarHBondContact O-N 3.16Å; Q252-L256 PolarHBondContact O-N 3.27Å; Q252-L256 VanDerWaalsContact O-N 3.07Å
253	K	84.6	Confident	76.8	Confident	131 Å²	131	64.4 Å²	64.4	57%	0.57	35%	0.35	S	S	*	.	H	α-helix	trans	-65.4	-36.7	177.6	-74.5	172.8	-178.7	179.9	0	112.2	R249 E250 T251 L256 L257	R249-K253 VanDerWaalsContact O-CG 3.25Å; R249-K253 WeakPolarHBondContact O-CG 3.47Å; R249-K253 PolarHBondContact O-N 3.25Å; E250-K253 PolarHBondContact O-N 3.21Å; T251-K253 VanDerWaalsContact C-N 3.34Å; T251-K253 PolarHBondContact O-N 3.2Å; K253-L256 PolarHBondContact O-N 2.94Å; K253-L257 WeakPolarHBondContact O-CB 3.43Å; K253-L257 PolarHBondContact O-N 3.29Å
254	A	85.4	Confident	79.5	Confident	21 Å²	21	61 Å²	61	17%	0.174	34%	0.342	C	S	.	.	H	α-helix	trans	-63.1	-47	177.7	0	0	0	0	0	111.1	I217 E250 T251 Q252 L256 L257 A258	I217-A254 HydrophobicContact CG2-CB 3.65Å; I217-A254 VanDerWaalsContact CG2-O 3.28Å; I217-A254 WeakPolarHBondContact CG2-O 3.35Å; E250-A254 WeakPolarHBondContact O-CB 3.48Å; E250-A254 PolarHBondContact O-N 3.17Å; T251-A254 WeakPolarHBondContact O-CB 3.31Å; T251-A254 PolarHBondContact O-N 3.18Å; T251-A254 VanDerWaalsContact O-N 3.13Å; Q252-A254 VanDerWaalsContact C-N 3.33Å; Q252-A254 PolarHBondContact O-N 3.47Å; A254-L256 VanDerWaalsContact C-N 3.34Å; A254-L256 PolarHBondContact O-N 2.86Å; A254-L257 PolarHBondContact O-N 3.16Å; A254-A258 WeakPolarHBondContact O-CB 3.35Å; A254-A258 PolarHBondContact O-N 3.38Å
255	Y	86.6	Confident	82.2	Confident	3 Å²	3	59.9 Å²	59.9	1%	0.012	32%	0.321	C	S	.	.	H	α-helix	trans	-59.8	-42.7	173.8	-86.2	-79.8	0	0	0	112.7	F66 Y70 V74 W147 V218 T251 Q252 A258 A259	F66-Y255 HydrophobicContact CB-CE1 4.09Å; Y70-Y255 AromaticContact CD2-CD1 3.77Å; Y70-Y255 HydrophobicContact CD2-CD1 3.77Å; Y70-Y255 AromaticContact CD2-CD2 3.69Å; Y70-Y255 HydrophobicContact CD2-CD2 3.69Å; Y70-Y255 HydrophobicContact CD2-CE1 4.03Å; Y70-Y255 AromaticContact CD2-CE2 3.97Å; Y70-Y255 HydrophobicContact CD2-CE2 3.97Å; Y70-Y255 AromaticContact CD2-CG 3.57Å; Y70-Y255 HydrophobicContact CD2-CG 3.57Å; Y70-Y255 HydrophobicContact CE2-CD1 4.44Å; Y70-Y255 HydrophobicContact CE2-CD2 4.2Å; Y70-Y255 AromaticContact CE2-CG 3.96Å; Y70-Y255 HydrophobicContact CE2-CG 3.96Å; Y70-Y255 HydrophobicContact CG-CD1 4.45Å; Y70-Y255 HydrophobicContact CG-CE1 4.43Å; V74-Y255 HydrophobicContact CG2-CD2 4.29Å; V74-Y255 HydrophobicContact CG2-CE2 3.92Å; W147-Y255 HydrophobicContact CD2-CD1 4.34Å; W147-Y255 AromaticContact CE3-CD1 3.34Å; W147-Y255 HydrophobicContact CE3-CD1 3.34Å; W147-Y255 AromaticContact CE3-CE1 3.99Å; W147-Y255 HydrophobicContact CE3-CE1 3.99Å; W147-Y255 HydrophobicContact CE3-CG 4.1Å; W147-Y255 HydrophobicContact CH2-CD1 4.07Å; W147-Y255 HydrophobicContact CH2-CE1 4.02Å; W147-Y255 AromaticContact CZ3-CD1 3.18Å; W147-Y255 HydrophobicContact CZ3-CD1 3.18Å; W147-Y255 AromaticContact CZ3-CE1 3.33Å; W147-Y255 HydrophobicContact CZ3-CE1 3.33Å; W147-Y255 HydrophobicContact CZ3-CG 4.27Å; V218-Y255 HydrophobicContact CB-CE2 4.38Å; V218-Y255 HydrophobicContact CG1-CE1 4.4Å; V218-Y255 HydrophobicContact CG1-CE2 3.72Å; V218-Y255 VanDerWaalsContact CG1-OH 3.26Å; V218-Y255 WeakPolarHBondContact CG1-OH 3.5Å; V218-Y255 HydrophobicContact CG2-CD1 3.99Å; V218-Y255 HydrophobicContact CG2-CD2 4.04Å; V218-Y255 HydrophobicContact CG2-CE1 3.63Å; V218-Y255 HydrophobicContact CG2-CE2 3.68Å; V218-Y255 HydrophobicContact CG2-CG 4.19Å; V218-Y255 VanDerWaalsContact CG2-CZ 3.5Å; T251-Y255 VanDerWaalsContact O-CD2 3.3Å; T251-Y255 WeakPolarHBondContact O-CD2 3.38Å; T251-Y255 PolarHBondContact O-N 3.08Å; Q252-Y255 PolarHBondContact O-N 3.16Å; Y255-A258 PolarHBondContact O-N 3.41Å; Y255-A259 WeakPolarHBondContact O-CB 3.09Å; Y255-A259 PolarHBondContact O-N 3.02Å
256	L	90.1	Very high	84.6	Confident	53 Å²	53	53.7 Å²	53.7	28%	0.277	28%	0.282	S	S	.	.	H	α-helix	trans	-66.4	-39.6	178.3	-165.1	70.3	0	0	0	112.3	F144 Q252 K253 A254 A259 G260	F144-L256 HydrophobicContact CD1-CD1 4.48Å; F144-L256 HydrophobicContact CD2-CD1 4.36Å; F144-L256 HydrophobicContact CE1-CD1 3.85Å; F144-L256 HydrophobicContact CE2-CD1 3.7Å; F144-L256 HydrophobicContact CE2-CG 3.98Å; F144-L256 HydrophobicContact CZ-CD1 3.41Å; F144-L256 VanDerWaalsContact CZ-CD1 3.41Å; F144-L256 HydrophobicContact CZ-CD2 4.21Å; F144-L256 HydrophobicContact CZ-CG 3.75Å; Q252-L256 PolarHBondContact O-N 3.27Å; Q252-L256 VanDerWaalsContact O-N 3.07Å; K253-L256 PolarHBondContact O-N 2.94Å; A254-L256 VanDerWaalsContact C-N 3.34Å; A254-L256 PolarHBondContact O-N 2.86Å; L256-A259 PolarHBondContact O-N 3.29Å; L256-G260 PolarHBondContact O-N 3.32Å
257	L	90.8	Very high	86.7	Confident	115 Å²	115	53.5 Å²	53.5	60%	0.602	28%	0.281	S	S	*	.	H	α-helix	trans	-64.1	-47.3	175.3	-179.4	67.8	0	0	0	111	K253 A254 A259 G260 V261	K253-L257 WeakPolarHBondContact O-CB 3.43Å; K253-L257 PolarHBondContact O-N 3.29Å; A254-L257 PolarHBondContact O-N 3.16Å; L257-A259 VanDerWaalsContact C-N 3.3Å; L257-A259 PolarHBondContact O-N 3.49Å; L257-G260 PolarHBondContact O-N 2.8Å; L257-V261 WeakPolarHBondContact O-CG2 3.48Å; L257-V261 PolarHBondContact O-N 3.4Å
258	A	90.1	Very high	88.2	Confident	0 Å²	0	55.3 Å²	55.3	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-58.1	-44.4	175.7	0	0	0	0	0	111.1	I213 I217 A254 Y255 G260 V261 I262	I213-A258 HydrophobicContact CG2-CB 4.22Å; I217-A258 HydrophobicContact CB-CB 4.42Å; I217-A258 HydrophobicContact CD1-CB 3.73Å; I217-A258 HydrophobicContact CG2-CB 4.18Å; A254-A258 WeakPolarHBondContact O-CB 3.35Å; A254-A258 PolarHBondContact O-N 3.38Å; Y255-A258 PolarHBondContact O-N 3.41Å; A258-G260 VanDerWaalsContact C-N 3.34Å; A258-G260 PolarHBondContact O-N 3.47Å; A258-V261 PolarHBondContact O-N 3.34Å; A258-I262 WeakPolarHBondContact O-CG1 3.15Å; A258-I262 PolarHBondContact O-N 3.15Å
259	A	91.8	Very high	89.6	Confident	0 Å²	0	51.1 Å²	51.1	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-61	-42.2	176.2	0	0	0	0	0	112.3	Y143 F144 W147 Y255 L256 L257 I262 V263	Y143-A259 HydrophobicContact CD1-CB 4.46Å; Y143-A259 HydrophobicContact CE1-CB 4.01Å; F144-A259 HydrophobicContact CD2-CB 4.42Å; W147-A259 HydrophobicContact CB-CB 3.86Å; W147-A259 HydrophobicContact CG-CB 3.69Å; Y255-A259 WeakPolarHBondContact O-CB 3.09Å; Y255-A259 PolarHBondContact O-N 3.02Å; L256-A259 PolarHBondContact O-N 3.29Å; L257-A259 VanDerWaalsContact C-N 3.3Å; L257-A259 PolarHBondContact O-N 3.49Å; A259-I262 PolarHBondContact O-N 2.95Å; A259-V263 WeakPolarHBondContact O-CB 3.36Å; A259-V263 WeakPolarHBondContact O-CG2 3.49Å; A259-V263 PolarHBondContact O-N 3.03Å
260	G	93.4	Very high	90.7	Very high	21 Å²	21	43.3 Å²	43.3	22%	0.216	24%	0.238	C	C	.	.	H	α-helix	trans	-60.6	-42.6	174.9	0	0	0	0	0	113.1	L256 L257 A258 V263 C264	L256-G260 PolarHBondContact O-N 3.32Å; L257-G260 PolarHBondContact O-N 2.8Å; A258-G260 VanDerWaalsContact C-N 3.34Å; A258-G260 PolarHBondContact O-N 3.47Å; G260-V263 PolarHBondContact O-N 3.09Å; G260-C264 PolarHBondContact O-N 2.68Å; G260-C264 PolarHBondContact O-SG 3.02Å
261	V	93.9	Very high	91.5	Very high	61 Å²	61	41.3 Å²	41.3	37%	0.37	23%	0.233	S	C	.	.	H	α-helix	trans	-63.9	-46.1	175.9	174.3	0	0	0	0	111.2	I213 L257 A258 V263 C264 I265	I213-V261 HydrophobicContact CD1-CG1 4.22Å; L257-V261 WeakPolarHBondContact O-CG2 3.48Å; L257-V261 PolarHBondContact O-N 3.4Å; A258-V261 PolarHBondContact O-N 3.34Å; V261-V263 VanDerWaalsContact C-N 3.31Å; V261-V263 PolarHBondContact O-N 3.12Å; V261-C264 WeakPolarHBondContact O-CB 3.48Å; V261-C264 PolarHBondContact O-N 3.44Å; V261-I265 HydrophobicContact CG1-CD1 4.03Å; V261-I265 WeakPolarHBondContact O-CG1 3.29Å; V261-I265 PolarHBondContact O-N 2.95Å
262	I	94.1	Very high	92.4	Very high	1 Å²	1	42.4 Å²	42.4	1%	0.005	24%	0.237	C	C	.	.	H	α-helix	trans	-61.4	-41.1	178.4	-70.4	169.6	0	0	0	111	V58 T59 A62 Y143 I213 A258 A259 I265 Y266	V58-I262 HydrophobicContact CG1-CB 4.33Å; V58-I262 HydrophobicContact CG1-CD1 4.37Å; V58-I262 HydrophobicContact CG1-CG1 3.89Å; V58-I262 HydrophobicContact CG1-CG2 3.74Å; T59-I262 HydrophobicContact CG2-CG2 3.59Å; A62-I262 HydrophobicContact CB-CD1 3.89Å; Y143-I262 HydrophobicContact CD1-CG2 4.49Å; Y143-I262 HydrophobicContact CE1-CB 3.99Å; Y143-I262 HydrophobicContact CE1-CG2 3.68Å; Y143-I262 VanDerWaalsContact OH-CD1 3.31Å; Y143-I262 WeakPolarHBondContact OH-CD1 3.35Å; I213-I262 HydrophobicContact CD1-CG1 4.44Å; I213-I262 HydrophobicContact CG2-CD1 4.37Å; I213-I262 HydrophobicContact CG2-CG1 4.22Å; A258-I262 WeakPolarHBondContact O-CG1 3.15Å; A258-I262 PolarHBondContact O-N 3.15Å; A259-I262 PolarHBondContact O-N 2.95Å; I262-I265 PolarHBondContact O-N 3.01Å; I262-Y266 WeakPolarHBondContact O-CB 3.33Å; I262-Y266 PolarHBondContact O-N 3.48Å
263	V	95.3	Very high	93.1	Very high	22 Å²	22	40.2 Å²	40.2	13%	0.133	23%	0.227	C	C	.	.	H	α-helix	trans	-59.7	-45.7	174.3	153.3	0	0	0	0	111.9	V140 Y143 F144 A259 G260 V261 I265 Y266 V267	V140-V263 HydrophobicContact CB-CG1 4.41Å; V140-V263 HydrophobicContact CG1-CB 4.13Å; V140-V263 HydrophobicContact CG1-CG1 3.24Å; V140-V263 HydrophobicContact CG1-CG2 3.91Å; V140-V263 HydrophobicContact CG2-CG1 4.47Å; Y143-V263 HydrophobicContact CD1-CG2 3.8Å; F144-V263 HydrophobicContact CB-CG2 4.46Å; A259-V263 WeakPolarHBondContact O-CB 3.36Å; A259-V263 WeakPolarHBondContact O-CG2 3.49Å; A259-V263 PolarHBondContact O-N 3.03Å; G260-V263 PolarHBondContact O-N 3.09Å; V261-V263 VanDerWaalsContact C-N 3.31Å; V261-V263 PolarHBondContact O-N 3.12Å; V263-I265 VanDerWaalsContact C-N 3.31Å; V263-I265 PolarHBondContact O-N 3.19Å; V263-Y266 WeakPolarHBondContact O-CB 3.25Å; V263-Y266 PolarHBondContact O-N 3.1Å; V263-V267 WeakPolarHBondContact O-CG2 3.23Å; V263-V267 PolarHBondContact O-N 3.33Å
264	C	95.8	Very high	93.4	Very high	75 Å²	75	36 Å²	36	51%	0.507	21%	0.212	S	C	.	.	H	α-helix	trans	-60.2	-43.8	177	-70.4	0	0	0	0	111.3	G260 V261 Y266 V267 I268	G260-C264 PolarHBondContact O-N 2.68Å; G260-C264 PolarHBondContact O-SG 3.02Å; V261-C264 WeakPolarHBondContact O-CB 3.48Å; V261-C264 PolarHBondContact O-N 3.44Å; C264-Y266 VanDerWaalsContact C-N 3.34Å; C264-Y266 PolarHBondContact O-N 3.08Å; C264-V267 PolarHBondContact O-N 2.7Å; C264-I268 WeakPolarHBondContact O-CB 3.49Å; C264-I268 WeakPolarHBondContact O-CD1 3.42Å; C264-I268 WeakPolarHBondContact O-CG1 3.15Å; C264-I268 PolarHBondContact O-N 2.91Å
265	I	95.3	Very high	93.6	Very high	38 Å²	38	41.8 Å²	41.8	20%	0.195	24%	0.239	C	C	.	.	H	α-helix	trans	-61.5	-43.8	175.8	-65.3	165.5	0	0	0	110.5	L209 I213 V261 I262 V263 V267 I268 C269	L209-I265 HydrophobicContact CD2-CD1 4.18Å; I213-I265 HydrophobicContact CD1-CD1 3.68Å; V261-I265 HydrophobicContact CG1-CD1 4.03Å; V261-I265 WeakPolarHBondContact O-CG1 3.29Å; V261-I265 PolarHBondContact O-N 2.95Å; I262-I265 PolarHBondContact O-N 3.01Å; V263-I265 VanDerWaalsContact C-N 3.31Å; V263-I265 PolarHBondContact O-N 3.19Å; I265-V267 PolarHBondContact O-N 3.38Å; I265-I268 PolarHBondContact O-N 3.04Å; I265-C269 WeakPolarHBondContact O-CB 3.2Å; I265-C269 PolarHBondContact O-N 2.97Å; I265-C269 PolarHBondContact O-SG 3.39Å
266	Y	95.9	Very high	93.7	Very high	3 Å²	3	43 Å²	43	1%	0.012	25%	0.252	C	S	.	.	H	α-helix	trans	-55.2	-53.9	176.9	-166.3	-58.2	0	0	0	110.7	P55 T59 T136 V140 F174 I262 V263 C264 I268 C269 A270	P55-Y266 HydrophobicContact CB-CD1 4.04Å; P55-Y266 HydrophobicContact CB-CD2 3.53Å; P55-Y266 HydrophobicContact CB-CE1 4.08Å; P55-Y266 HydrophobicContact CB-CE2 3.6Å; P55-Y266 HydrophobicContact CB-CG 3.73Å; P55-Y266 HydrophobicContact CG-CD1 4.45Å; P55-Y266 HydrophobicContact CG-CG 4.38Å; T59-Y266 HydrophobicContact CG2-CD2 3.88Å; T59-Y266 HydrophobicContact CG2-CE2 4.37Å; T136-Y266 HydrophobicContact CG2-CD1 3.95Å; T136-Y266 HydrophobicContact CG2-CE1 3.8Å; V140-Y266 HydrophobicContact CG2-CD1 3.81Å; V140-Y266 HydrophobicContact CG2-CE1 4.46Å; V140-Y266 HydrophobicContact CG2-CG 3.96Å; F174-Y266 HydrophobicContact CD2-CE1 4.13Å; F174-Y266 WeakPolarHBondContact CD2-OH 3.32Å; F174-Y266 HydrophobicContact CE2-CE1 4.06Å; F174-Y266 WeakPolarHBondContact CG-OH 3.19Å; I262-Y266 WeakPolarHBondContact O-CB 3.33Å; I262-Y266 PolarHBondContact O-N 3.48Å; V263-Y266 WeakPolarHBondContact O-CB 3.25Å; V263-Y266 PolarHBondContact O-N 3.1Å; C264-Y266 VanDerWaalsContact C-N 3.34Å; C264-Y266 PolarHBondContact O-N 3.08Å; Y266-I268 PolarHBondContact O-N 3.26Å; Y266-C269 PolarHBondContact O-N 3.01Å; Y266-A270 WeakPolarHBondContact O-CB 3.22Å; Y266-A270 PolarHBondContact O-N 2.96Å
267	V	96.8	Very high	93.8	Very high	60 Å²	60	40.9 Å²	40.9	36%	0.364	24%	0.241	S	C	.	.	H	α-helix	trans	-62.3	-45.6	-177.9	174.9	0	0	0	0	111.1	V140 V263 C264 I265 C269 A270 V271	V140-V267 HydrophobicContact CG1-CG2 4.35Å; V140-V267 HydrophobicContact CG2-CG2 3.77Å; V263-V267 WeakPolarHBondContact O-CG2 3.23Å; V263-V267 PolarHBondContact O-N 3.33Å; C264-V267 PolarHBondContact O-N 2.7Å; I265-V267 PolarHBondContact O-N 3.38Å; V267-C269 VanDerWaalsContact C-N 3.35Å; V267-C269 PolarHBondContact O-N 3.17Å; V267-A270 PolarHBondContact O-N 3.05Å; V267-V271 HydrophobicContact CG1-CG2 4.31Å; V267-V271 VanDerWaalsContact O-CG2 3.29Å; V267-V271 WeakPolarHBondContact O-CG2 3.22Å; V267-V271 PolarHBondContact O-N 3.46Å
268	I	96.8	Very high	93.5	Very high	100 Å²	100	45.9 Å²	45.9	51%	0.513	25%	0.252	S	S	.	.	H	α-helix	trans	-59.2	-47.1	179	-69.7	165.6	0	0	0	110.5	C264 I265 Y266 A270 V271 I272	C264-I268 WeakPolarHBondContact O-CB 3.49Å; C264-I268 WeakPolarHBondContact O-CD1 3.42Å; C264-I268 WeakPolarHBondContact O-CG1 3.15Å; C264-I268 PolarHBondContact O-N 2.91Å; I265-I268 PolarHBondContact O-N 3.04Å; Y266-I268 PolarHBondContact O-N 3.26Å; I268-A270 PolarHBondContact O-N 2.9Å; I268-V271 PolarHBondContact O-N 3.11Å; I268-I272 HydrophobicContact CG2-CD1 3.74Å; I268-I272 HydrophobicContact CG2-CG1 4.49Å; I268-I272 VanDerWaalsContact O-CG1 3.26Å; I268-I272 WeakPolarHBondContact O-CG1 3.45Å; I268-I272 PolarHBondContact O-N 3.3Å
269	C	96.3	Very high	93.4	Very high	9 Å²	9	46.8 Å²	46.8	6%	0.061	26%	0.257	C	S	.	.	H	α-helix	trans	-64.3	-41.1	179.3	-68	0	0	0	0	112.3	L51 P55 I265 Y266 V267 I272 L273	L51-C269 WeakPolarHBondContact O-CB 3.29Å; P55-C269 HydrophobicContact CG-CB 3.5Å; P55-C269 VanDerWaalsContact CG-CB 3.5Å; I265-C269 WeakPolarHBondContact O-CB 3.2Å; I265-C269 PolarHBondContact O-N 2.97Å; I265-C269 PolarHBondContact O-SG 3.39Å; Y266-C269 PolarHBondContact O-N 3.01Å; V267-C269 VanDerWaalsContact C-N 3.35Å; V267-C269 PolarHBondContact O-N 3.17Å; C269-I272 PolarHBondContact O-N 3.28Å; C269-L273 WeakPolarHBondContact O-CB 3.44Å; C269-L273 PolarHBondContact O-N 3.49Å
270	A	94.9	Very high	93	Very high	4 Å²	4	49.9 Å²	49.9	3%	0.033	27%	0.271	C	S	.	.	H	α-helix	trans	-65.2	-39.3	176.8	0	0	0	0	0	112.3	T136 F174 Y266 V267 I268 L273 T274	T136-A270 HydrophobicContact CG2-CB 3.77Å; F174-A270 HydrophobicContact CE2-CB 4Å; Y266-A270 WeakPolarHBondContact O-CB 3.22Å; Y266-A270 PolarHBondContact O-N 2.96Å; V267-A270 PolarHBondContact O-N 3.05Å; I268-A270 PolarHBondContact O-N 2.9Å; A270-L273 PolarHBondContact O-N 3.47Å; A270-T274 WeakPolarHBondContact O-CB 3.11Å; A270-T274 WeakPolarHBondContact O-CG2 3.46Å; A270-T274 PolarHBondContact O-N 3.28Å; A270-T274 PolarHBondContact O-OG1 3.43Å
271	V	95.8	Very high	92.1	Very high	70 Å²	70	54.8 Å²	54.8	42%	0.424	28%	0.283	S	S	.	.	H	α-helix	trans	-65.1	-43.9	174.5	171.4	0	0	0	0	110.7	V267 I268 L273 T274 L275	V267-V271 HydrophobicContact CG1-CG2 4.31Å; V267-V271 VanDerWaalsContact O-CG2 3.29Å; V267-V271 WeakPolarHBondContact O-CG2 3.22Å; V267-V271 PolarHBondContact O-N 3.46Å; I268-V271 PolarHBondContact O-N 3.11Å; V271-L273 VanDerWaalsContact C-N 3.35Å; V271-L273 PolarHBondContact O-N 2.87Å; V271-T274 WeakPolarHBondContact CA-OG1 3.45Å; V271-T274 PolarHBondContact O-N 3.38Å; V271-T274 PolarHBondContact O-OG1 3.05Å; V271-T274 VanDerWaalsContact O-OG1 3.07Å; V271-L275 HydrophobicContact CG1-CD1 3.63Å; V271-L275 HydrophobicContact CG1-CG 4.25Å; V271-L275 WeakPolarHBondContact O-CB 3.33Å; V271-L275 VanDerWaalsContact O-CG 3.29Å; V271-L275 WeakPolarHBondContact O-CG 3.47Å; V271-L275 PolarHBondContact O-N 2.93Å
272	I	95.9	Very high	90.9	Very high	58 Å²	58	52.9 Å²	52.9	30%	0.297	27%	0.27	S	S	.	.	H	α-helix	trans	-62.7	-42.5	177.4	-68	166.6	0	0	0	111.3	C48 L51 I268 C269 G276	C48-I272 HydrophobicContact CB-CG2 4.01Å; L51-I272 HydrophobicContact CB-CG2 4.36Å; L51-I272 HydrophobicContact CD1-CD1 4.11Å; L51-I272 HydrophobicContact CD1-CG2 3.77Å; I268-I272 HydrophobicContact CG2-CD1 3.74Å; I268-I272 HydrophobicContact CG2-CG1 4.49Å; I268-I272 VanDerWaalsContact O-CG1 3.26Å; I268-I272 WeakPolarHBondContact O-CG1 3.45Å; I268-I272 PolarHBondContact O-N 3.3Å; C269-I272 PolarHBondContact O-N 3.28Å; I272-G276 WeakPolarHBondContact O-CA 3.08Å; I272-G276 PolarHBondContact O-N 3.36Å
273	L	94.8	Very high	89.1	Confident	0 Å²	0	57.2 Å²	57.2	0%	0	30%	0.299	C	S	.	.	H	α-helix	trans	-60.4	-50.2	177	175.1	65.8	0	0	0	111.5	Y49 I132 F174 Y178 L181 C269 A270 V271 G276 V277	Y49-L273 HydrophobicContact CD2-CD1 4.37Å; I132-L273 HydrophobicContact CD1-CD2 4.08Å; I132-L273 HydrophobicContact CG2-CD2 4.01Å; F174-L273 HydrophobicContact CZ-CD2 4.21Å; Y178-L273 HydrophobicContact CD2-CD1 4.14Å; Y178-L273 HydrophobicContact CD2-CD2 3.73Å; Y178-L273 HydrophobicContact CE2-CD1 3.98Å; Y178-L273 HydrophobicContact CE2-CD2 4.21Å; L181-L273 HydrophobicContact CD2-CD1 4.15Å; C269-L273 WeakPolarHBondContact O-CB 3.44Å; C269-L273 PolarHBondContact O-N 3.49Å; A270-L273 PolarHBondContact O-N 3.47Å; V271-L273 VanDerWaalsContact C-N 3.35Å; V271-L273 PolarHBondContact O-N 2.87Å; L273-G276 PolarHBondContact O-N 2.74Å; L273-V277 HydrophobicContact CD1-CB 4.38Å; L273-V277 HydrophobicContact CD1-CG2 3.95Å; L273-V277 WeakPolarHBondContact O-CB 3.33Å; L273-V277 PolarHBondContact O-N 3.09Å; L273-V277 VanDerWaalsContact O-N 3.07Å
274	T	91.2	Very high	87.3	Confident	41 Å²	41	57.8 Å²	57.8	25%	0.252	30%	0.299	S	S	.	.	H	α-helix	trans	-70.9	-32.2	-174.2	53	0	0	0	0	113.1	M129 I132 I133 A270 V271	M129-T274 HydrophobicContact SD-CG2 4.31Å; I132-T274 HydrophobicContact CG2-CG2 4.3Å; I133-T274 HydrophobicContact CD1-CG2 4.04Å; I133-T274 HydrophobicContact CG1-CG2 3.47Å; I133-T274 VanDerWaalsContact CG1-CG2 3.47Å; A270-T274 WeakPolarHBondContact O-CB 3.11Å; A270-T274 WeakPolarHBondContact O-CG2 3.46Å; A270-T274 PolarHBondContact O-N 3.28Å; A270-T274 PolarHBondContact O-OG1 3.43Å; V271-T274 WeakPolarHBondContact CA-OG1 3.45Å; V271-T274 PolarHBondContact O-N 3.38Å; V271-T274 PolarHBondContact O-OG1 3.05Å; V271-T274 VanDerWaalsContact O-OG1 3.07Å
275	L	91.1	Very high	85.6	Confident	144 Å²	144	55 Å²	55	75%	0.754	28%	0.278	S	S	*	.	H	α-helix	trans	-84	-31.9	175.3	-63.6	178.6	0	0	0	113.1	V271	V271-L275 HydrophobicContact CG1-CD1 3.63Å; V271-L275 HydrophobicContact CG1-CG 4.25Å; V271-L275 WeakPolarHBondContact O-CB 3.33Å; V271-L275 VanDerWaalsContact O-CG 3.29Å; V271-L275 WeakPolarHBondContact O-CG 3.47Å; V271-L275 PolarHBondContact O-N 2.93Å
276	G	88.1	Confident	83.8	Confident	27 Å²	27	55.8 Å²	55.8	28%	0.278	29%	0.29	S	S	.	.	H	α-helix	trans	-92.3	-18.4	-171.1	0	0	0	0	0	115.3	I272 L273	I272-G276 WeakPolarHBondContact O-CA 3.08Å; I272-G276 PolarHBondContact O-N 3.36Å; L273-G276 PolarHBondContact O-N 2.74Å
277	V	90.8	Very high	81.6	Confident	9 Å²	9	61.3 Å²	61.3	6%	0.055	32%	0.316	C	S	.	.			trans	-118.9	134.8	-177.3	-177.1	0	0	0	0	110.1	C48 M129 L181 I185 L273	C48-V277 HydrophobicContact CB-CG2 4.2Å; M129-V277 HydrophobicContact CE-CB 3.8Å; M129-V277 HydrophobicContact CE-CG1 3.87Å; M129-V277 WeakPolarHBondContact CE-O 3.44Å; L181-V277 HydrophobicContact CD2-CG1 3.97Å; L181-V277 HydrophobicContact CG-CG1 4.43Å; I185-V277 HydrophobicContact CD1-CG1 3.85Å; I185-V277 HydrophobicContact CG1-CG1 4.09Å; L273-V277 HydrophobicContact CD1-CB 4.38Å; L273-V277 HydrophobicContact CD1-CG2 3.95Å; L273-V277 WeakPolarHBondContact O-CB 3.33Å; L273-V277 PolarHBondContact O-N 3.09Å; L273-V277 VanDerWaalsContact O-N 3.07Å
278	R	85.9	Confident	79.4	Confident	220 Å²	220	63.8 Å²	63.8	83%	0.83	32%	0.324	S	S	*	.			trans	-120.9	130.6	175.4	-169.4	172.7	-178	176	0.8	109.6
279	E	87.6	Confident	77.5	Confident	19 Å²	19	62.4 Å²	62.4	9%	0.089	33%	0.327	C	S	.	.	P	Polyproline II helix	trans	-67.8	135.6	175.6	-70.9	-179.5	-130.3	0	0	111.3	W122 R127 L128 M129 L181	W122-E279 HydrophobicContact CZ3-CB 4.33Å; R127-E279 PolarHBondContact N-OE1 3.01Å; R127-E279 PolarHBondContact N-OE2 3.07Å; L128-E279 WeakPolarHBondContact CA-OE1 3.3Å; L128-E279 WeakPolarHBondContact CB-OE1 3.31Å; L128-E279 PolarHBondContact N-OE1 2.84Å; L128-E279 PolarHBondContact N-OE2 2.89Å; L128-E279 VanDerWaalsContact N-OE2 3.15Å; M129-E279 WeakPolarHBondContact CB-OE1 3.47Å; M129-E279 HydrophobicContact CG-CG 4.2Å; M129-E279 WeakPolarHBondContact CG-OE1 3.46Å; M129-E279 PolarHBondContact N-OE1 3.04Å; L181-E279 HydrophobicContact CD1-CG 3.57Å
280	Q	82.8	Confident	76	Confident	65 Å²	65	68.9 Å²	68.9	30%	0.304	36%	0.357	S	S	.	.	P	Polyproline II helix	trans	-101.1	123.9	170.6	-59.7	-171.9	-17.4	0	0	109.1	F184	F184-Q280 WeakPolarHBondContact O-CB 3.35Å; F184-Q280 PolarHBondContact O-N 3.46Å
281	R	74.1	Confident	74.5	Confident	125 Å²	125	74.8 Å²	74.8	47%	0.472	39%	0.394	S	S	.	.	P	Polyproline II helix	trans	-88.2	127.7	172.1	-171.9	170.8	-175.8	-174.9	0.2	109.3	W122	W122-R281 HydrophobicContact CD2-CB 4.47Å; W122-R281 HydrophobicContact CD2-CG 4.06Å; W122-R281 HydrophobicContact CE3-CB 4.08Å; W122-R281 HydrophobicContact CE3-CG 4.18Å; W122-R281 VanDerWaalsContact CH2-CA 3.44Å; W122-R281 HydrophobicContact CH2-CB 3.48Å; W122-R281 VanDerWaalsContact CH2-CB 3.48Å; W122-R281 HydrophobicContact CH2-CG 3.77Å; W122-R281 HydrophobicContact CZ2-CB 3.9Å; W122-R281 HydrophobicContact CZ2-CG 3.6Å; W122-R281 HydrophobicContact CZ3-CB 3.58Å; W122-R281 HydrophobicContact CZ3-CG 4.05Å
282	E	69	Low	73.3	Confident	20 Å²	20	73 Å²	73	9%	0.093	38%	0.382	C	S	.	.	P	Polyproline II helix	trans	-76.9	132.2	171.9	-69	-158.5	134.3	0	0	110.1	T187 Y284 E285 R523	T187-E282 HydrophobicContact CG2-CG 4.33Å; T187-E282 VanDerWaalsContact CG2-OE1 3.23Å; T187-E282 WeakPolarHBondContact CG2-OE1 3.27Å; E282-Y284 VanDerWaalsContact C-N 3.29Å; E282-Y284 HydrophobicContact CB-CD1 4.08Å; E282-Y284 HydrophobicContact CB-CE1 3.71Å; E282-Y284 HydrophobicContact CG-CE1 4.27Å; E282-Y284 PolarHBondContact O-N 2.94Å; E282-Y284 WeakPolarHBondContact OE2-CE1 3.37Å; E282-Y284 PolarHBondContact OE2-OH 2.93Å; E282-E285 HydrophobicContact CB-CG 4.1Å; E282-E285 WeakPolarHBondContact O-CB 3.15Å; E282-E285 PolarHBondContact O-N 3.38Å; E282-R523 IonicContact OE1-CZ 2.68Å; E282-R523 IonicContact OE1-NE 3.99Å; E282-R523 PolarHBondContact OE1-NE 3.02Å; E282-R523 IonicContact OE1-NH2 3.43Å; E282-R523 PolarHBondContact OE1-NH2 2.9Å
283	P	56.8	Low	72.6	Confident	93 Å²	93	73 Å²	73	60%	0.604	39%	0.391	S	S	*	.	G	3₁₀ helix	trans	-59.1	-34.8	-173.7	-26.7	34.1	0	0	0	114.6	A286	P283-A286 WeakPolarHBondContact O-CB 3.43Å; P283-A286 PolarHBondContact O-N 3.28Å
284	Y	58.4	Low	71.7	Confident	34 Å²	34	75 Å²	75	13%	0.133	40%	0.399	C	S	.	.	G	3₁₀ helix	trans	-74.2	-25.4	-178.1	68.8	-94.2	0	0	0	112.9	E282 A286 Q287 H434	E282-Y284 VanDerWaalsContact C-N 3.29Å; E282-Y284 HydrophobicContact CB-CD1 4.08Å; E282-Y284 HydrophobicContact CB-CE1 3.71Å; E282-Y284 HydrophobicContact CG-CE1 4.27Å; E282-Y284 PolarHBondContact O-N 2.94Å; E282-Y284 WeakPolarHBondContact OE2-CE1 3.37Å; E282-Y284 PolarHBondContact OE2-OH 2.93Å; Y284-A286 PolarHBondContact O-N 3.16Å; Y284-A286 VanDerWaalsContact O-N 3.17Å; Y284-Q287 PolarHBondContact O-N 3.23Å; Y284-H434 AromaticContact CD2-CE1 3.56Å; Y284-H434 AromaticContact CE2-CE1 3.41Å; Y284-H434 VanDerWaalsContact CE2-CE1 3.41Å; Y284-H434 WeakPolarHBondContact CE2-CE1 3.46Å; Y284-H434 AromaticContact CE2-ND1 3.88Å
285	E	59.7	Low	71.2	Confident	16 Å²	16	80.9 Å²	80.9	8%	0.075	42%	0.421	C	S	.	.	G	3₁₀ helix	trans	-63.8	-21.1	175.4	-68.6	-177.3	165.3	0	0	112.4	E282	E282-E285 HydrophobicContact CB-CG 4.1Å; E282-E285 WeakPolarHBondContact O-CB 3.15Å; E282-E285 PolarHBondContact O-N 3.38Å
286	A	56.6	Low	70.8	Confident	55 Å²	55	79.3 Å²	79.3	46%	0.455	41%	0.41	S	S	.	.	G	3₁₀ helix	trans	-77.2	-19.7	179.6	0	0	0	0	0	113.6	P283 Y284	P283-A286 WeakPolarHBondContact O-CB 3.43Å; P283-A286 PolarHBondContact O-N 3.28Å; Y284-A286 PolarHBondContact O-N 3.16Å; Y284-A286 VanDerWaalsContact O-N 3.17Å
287	Q	51.1	Low	70.6	Confident	118 Å²	118	78.1 Å²	78.1	55%	0.551	40%	0.397	S	S	*	.	T	Hydrogen-bonded Turn	trans	-99.3	-14.8	-165.9	-73.7	178.8	-22.8	0	0	114.6	Y284	Y284-Q287 PolarHBondContact O-N 3.23Å
288	Q	50.7	Low	70.3	Confident	112 Å²	112	79.3 Å²	79.3	52%	0.523	40%	0.403	S	S	.	.			trans	-143.3	19.7	-166.2	-62.3	-171	-4.3	0	0	117.3	E290	Q288-E290 PolarHBondContact O-N 2.85Å
289	A	56.7	Low	70.4	Confident	71 Å²	71	78.5 Å²	78.5	59%	0.587	40%	0.4	S	S	*	.			trans	-80.7	103.5	-174.3	0	0	0	0	0	113.7
290	E	63.8	Low	70.3	Confident	146 Å²	146	79 Å²	79	68%	0.682	40%	0.403	S	S	*	.	P	Polyproline II helix	trans	-76.9	136.2	161	-73.5	-167	170.4	0	0	110.8	Q288 I292	Q288-E290 PolarHBondContact O-N 2.85Å; E290-I292 PolarHBondContact O-N 3.46Å
291	P	63.8	Low	70.6	Confident	127 Å²	127	76 Å²	76	83%	0.825	39%	0.389	S	S	*	.	P	Polyproline II helix	trans	-70	117.1	177.1	27.3	-32	0	0	0	110.8
292	I	71.6	Confident	71.4	Confident	33 Å²	33	73 Å²	73	17%	0.169	38%	0.381	C	S	.	.	P	Polyproline II helix	trans	-88	135.2	-179.1	-44.8	172.8	0	0	0	110.3	E290 Q296 F433 T436	E290-I292 PolarHBondContact O-N 3.46Å; I292-Q296 HydrophobicContact CG2-CB 4.16Å; I292-Q296 HydrophobicContact CG2-CG 4.26Å; I292-F433 HydrophobicContact CD1-CB 3.86Å; I292-F433 HydrophobicContact CD1-CD1 3.36Å; I292-F433 HydrophobicContact CD1-CE1 4.24Å; I292-F433 HydrophobicContact CD1-CG 3.99Å; I292-F433 HydrophobicContact CG1-CD1 3.67Å; I292-F433 HydrophobicContact CG1-CE1 4.17Å; I292-T436 HydrophobicContact CD1-CG2 3.77Å
293	A	80.6	Confident	72.4	Confident	57 Å²	57	76 Å²	76	47%	0.471	40%	0.404	S	S	.	.	P	Polyproline II helix	trans	-69.4	145.8	170	0	0	0	0	0	111.6	F295 Q296 G297	A293-F295 PolarHBondContact O-N 3.43Å; A293-Q296 HydrophobicContact CB-CB 4.22Å; A293-Q296 WeakPolarHBondContact O-CB 3.42Å; A293-Q296 PolarHBondContact O-N 3.23Å; A293-G297 PolarHBondContact O-N 3.48Å
294	Y	75.8	Confident	74.1	Confident	44 Å²	44	72.3 Å²	72.3	17%	0.173	38%	0.379	C	S	.	.	H	α-helix	trans	-50.2	-57.1	-174.3	176	-122	0	0	0	114.2	P111 F115 Q296 G297 L298	P111-Y294 WeakPolarHBondContact CB-OH 3.46Å; F115-Y294 HydrophobicContact CB-CD2 3.32Å; F115-Y294 HydrophobicContact CB-CE2 3.57Å; F115-Y294 HydrophobicContact CB-CG 4.37Å; F115-Y294 AromaticContact CD1-CD2 3.84Å; F115-Y294 HydrophobicContact CD1-CD2 3.84Å; F115-Y294 HydrophobicContact CD1-CG 4.1Å; F115-Y294 AromaticContact CD2-CD2 3.47Å; F115-Y294 HydrophobicContact CD2-CD2 3.47Å; F115-Y294 VanDerWaalsContact CD2-CD2 3.47Å; F115-Y294 HydrophobicContact CD2-CG 4.07Å; F115-Y294 HydrophobicContact CE1-CG 4.44Å; F115-Y294 HydrophobicContact CE2-CD2 4.23Å; F115-Y294 HydrophobicContact CE2-CG 4.41Å; F115-Y294 VanDerWaalsContact CE2-N 3.28Å; F115-Y294 AromaticContact CG-CD2 3.22Å; F115-Y294 HydrophobicContact CG-CD2 3.22Å; F115-Y294 HydrophobicContact CG-CE2 4.02Å; F115-Y294 AromaticContact CG-CG 3.89Å; F115-Y294 HydrophobicContact CG-CG 3.89Å; Y294-Q296 PolarHBondContact O-N 2.87Å; Y294-G297 PolarHBondContact O-N 2.96Å; Y294-L298 WeakPolarHBondContact O-CB 3.3Å; Y294-L298 PolarHBondContact O-N 3.48Å
295	F	80.7	Confident	75.8	Confident	164 Å²	164	72.5 Å²	72.5	72%	0.719	39%	0.391	S	S	*	.	H	α-helix	trans	-66.3	-28.7	-177.8	-69.8	-75.4	0	0	0	112.5	A293 R299	A293-F295 PolarHBondContact O-N 3.43Å; F295-R299 WeakPolarHBondContact O-CB 3.37Å; F295-R299 PolarHBondContact O-N 3.42Å
296	Q	83.4	Confident	77.4	Confident	111 Å²	111	72.3 Å²	72.3	52%	0.519	39%	0.391	S	S	.	.	H	α-helix	trans	-71.6	-44.6	175.5	-172.3	175.7	3.9	0	0	110.8	I292 A293 Y294 R299 L300	I292-Q296 HydrophobicContact CG2-CB 4.16Å; I292-Q296 HydrophobicContact CG2-CG 4.26Å; A293-Q296 HydrophobicContact CB-CB 4.22Å; A293-Q296 WeakPolarHBondContact O-CB 3.42Å; A293-Q296 PolarHBondContact O-N 3.23Å; Y294-Q296 PolarHBondContact O-N 2.87Å; Q296-R299 PolarHBondContact O-N 2.99Å; Q296-L300 VanDerWaalsContact O-CB 3.23Å; Q296-L300 WeakPolarHBondContact O-CB 3.42Å; Q296-L300 PolarHBondContact O-N 3.02Å
297	G	82.1	Confident	79.2	Confident	1 Å²	1	69.7 Å²	69.7	1%	0.01	37%	0.37	C	S	.	.	H	α-helix	trans	-61.1	-47.1	174.4	0	0	0	0	0	111.9	A293 Y294 R299 L300 V301	A293-G297 PolarHBondContact O-N 3.48Å; Y294-G297 PolarHBondContact O-N 2.96Å; G297-R299 PolarHBondContact O-N 3.19Å; G297-L300 WeakPolarHBondContact O-CB 3.43Å; G297-L300 PolarHBondContact O-N 3.49Å; G297-V301 WeakPolarHBondContact O-CG2 3.5Å; G297-V301 PolarHBondContact O-N 2.9Å
298	L	84.4	Confident	81.3	Confident	34 Å²	34	66 Å²	66	18%	0.178	36%	0.355	C	S	.	.	H	α-helix	trans	-60.7	-46.6	176.9	-178.6	63	0	0	0	112	Y294 L300 V301 M302 F443	Y294-L298 WeakPolarHBondContact O-CB 3.3Å; Y294-L298 PolarHBondContact O-N 3.48Å; L298-L300 VanDerWaalsContact C-N 3.29Å; L298-L300 PolarHBondContact O-N 3.09Å; L298-V301 PolarHBondContact O-N 3.42Å; L298-M302 HydrophobicContact CD1-CG 4.34Å; L298-M302 WeakPolarHBondContact O-CB 3.43Å; L298-M302 WeakPolarHBondContact O-CG 3.39Å; L298-M302 PolarHBondContact O-N 2.93Å; L298-F443 HydrophobicContact CD1-CD2 3.7Å; L298-F443 HydrophobicContact CD1-CE2 3.71Å; L298-F443 HydrophobicContact CD1-CG 4.18Å; L298-F443 HydrophobicContact CD1-CZ 4.16Å
299	R	87.8	Confident	83.4	Confident	203 Å²	203	64.7 Å²	64.7	77%	0.766	35%	0.348	S	S	*	.	H	α-helix	trans	-62.9	-38.2	177.3	-176.9	176.2	-179	174.9	0.8	111.6	F295 Q296 G297 M302 S303	F295-R299 WeakPolarHBondContact O-CB 3.37Å; F295-R299 PolarHBondContact O-N 3.42Å; Q296-R299 PolarHBondContact O-N 2.99Å; G297-R299 PolarHBondContact O-N 3.19Å; R299-M302 PolarHBondContact O-N 3.46Å; R299-S303 VanDerWaalsContact O-CB 3.31Å; R299-S303 WeakPolarHBondContact O-CB 3.4Å; R299-S303 PolarHBondContact O-N 2.62Å; R299-S303 PolarHBondContact O-OG 3.24Å
300	L	87.2	Confident	85.2	Confident	31 Å²	31	61.4 Å²	61.4	16%	0.162	32%	0.32	C	S	.	.	H	α-helix	trans	-64.6	-50.8	178.2	-174.7	64.6	0	0	0	110.5	Q296 G297 L298 M302 S303 H304 F426 F433	Q296-L300 VanDerWaalsContact O-CB 3.23Å; Q296-L300 WeakPolarHBondContact O-CB 3.42Å; Q296-L300 PolarHBondContact O-N 3.02Å; G297-L300 WeakPolarHBondContact O-CB 3.43Å; G297-L300 PolarHBondContact O-N 3.49Å; L298-L300 VanDerWaalsContact C-N 3.29Å; L298-L300 PolarHBondContact O-N 3.09Å; L300-M302 VanDerWaalsContact C-N 3.32Å; L300-M302 PolarHBondContact O-N 2.9Å; L300-S303 PolarHBondContact O-N 3.04Å; L300-S303 VanDerWaalsContact O-N 3.12Å; L300-S303 PolarHBondContact O-OG 3.2Å; L300-H304 PolarHBondContact O-N 3.5Å; L300-F426 HydrophobicContact CD2-CE2 4.43Å; L300-F426 HydrophobicContact CD2-CZ 3.74Å; L300-F426 HydrophobicContact CG-CE2 4.02Å; L300-F426 HydrophobicContact CG-CZ 3.8Å; L300-F433 HydrophobicContact CD2-CB 4.08Å; L300-F433 HydrophobicContact CD2-CD1 4.25Å; L300-F433 HydrophobicContact CD2-CD2 3.48Å; L300-F433 VanDerWaalsContact CD2-CD2 3.48Å; L300-F433 HydrophobicContact CD2-CE2 3.87Å; L300-F433 HydrophobicContact CD2-CG 3.67Å; L300-F433 HydrophobicContact CD2-CZ 4.39Å
301	V	88.8	Confident	86.6	Confident	0 Å²	0	54.7 Å²	54.7	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-57.1	-46.1	175.7	170.2	0	0	0	0	111	G297 L298 S303 H304 Y307 I439 F440	G297-V301 WeakPolarHBondContact O-CG2 3.5Å; G297-V301 PolarHBondContact O-N 2.9Å; L298-V301 PolarHBondContact O-N 3.42Å; V301-S303 VanDerWaalsContact C-N 3.28Å; V301-S303 PolarHBondContact O-N 2.99Å; V301-H304 WeakPolarHBondContact O-CB 3.34Å; V301-H304 PolarHBondContact O-N 2.86Å; V301-H304 VanDerWaalsContact O-N 3.12Å; V301-Y307 HydrophobicContact CG1-CD1 3.63Å; V301-Y307 HydrophobicContact CG1-CE1 3.27Å; V301-Y307 HydrophobicContact CG1-CG 4.49Å; V301-Y307 WeakPolarHBondContact O-CD1 3.44Å; V301-I439 HydrophobicContact CG2-CG2 4.09Å; V301-F440 HydrophobicContact CB-CE1 4.5Å; V301-F440 HydrophobicContact CB-CZ 4.28Å; V301-F440 HydrophobicContact CG1-CD1 3.87Å; V301-F440 HydrophobicContact CG1-CD2 4.47Å; V301-F440 HydrophobicContact CG1-CE1 3.71Å; V301-F440 HydrophobicContact CG1-CE2 4.35Å; V301-F440 HydrophobicContact CG1-CG 4.22Å; V301-F440 HydrophobicContact CG1-CZ 3.95Å; V301-F440 HydrophobicContact CG2-CD2 4.07Å; V301-F440 HydrophobicContact CG2-CE1 4.43Å; V301-F440 HydrophobicContact CG2-CE2 3.66Å; V301-F440 HydrophobicContact CG2-CZ 3.84Å
302	M	89.9	Confident	88.1	Confident	63 Å²	63	50.7 Å²	50.7	31%	0.31	26%	0.262	S	S	.	.	H	α-helix	trans	-74.6	-12.4	179.5	-75.7	-55.5	-65	0	0	115.5	L298 R299 L300 Y307 V308 F443	L298-M302 HydrophobicContact CD1-CG 4.34Å; L298-M302 WeakPolarHBondContact O-CB 3.43Å; L298-M302 WeakPolarHBondContact O-CG 3.39Å; L298-M302 PolarHBondContact O-N 2.93Å; R299-M302 PolarHBondContact O-N 3.46Å; L300-M302 VanDerWaalsContact C-N 3.32Å; L300-M302 PolarHBondContact O-N 2.9Å; M302-Y307 HydrophobicContact SD-CD1 4.28Å; M302-Y307 HydrophobicContact SD-CE1 4.03Å; M302-V308 HydrophobicContact CE-CG2 3.93Å; M302-V308 WeakPolarHBondContact O-CG2 3.38Å; M302-V308 HydrophobicContact SD-CG2 4.34Å; M302-F443 HydrophobicContact CE-CE1 4.04Å; M302-F443 HydrophobicContact CG-CD1 4.34Å; M302-F443 HydrophobicContact CG-CE1 3.75Å; M302-F443 HydrophobicContact CG-CZ 4.24Å; M302-F443 HydrophobicContact SD-CD1 3.7Å; M302-F443 HydrophobicContact SD-CE1 3.19Å; M302-F443 WeakPolarHBondContact SD-CE1 3.01Å; M302-F443 HydrophobicContact SD-CZ 4.15Å
303	S	90.6	Very high	89.2	Confident	83 Å²	83	49.1 Å²	49.1	58%	0.58	25%	0.254	S	S	*	.	H	α-helix	trans	-86.9	-11.4	170	66.3	0	0	0	0	112.5	R299 L300 V301 G305	R299-S303 VanDerWaalsContact O-CB 3.31Å; R299-S303 WeakPolarHBondContact O-CB 3.4Å; R299-S303 PolarHBondContact O-N 2.62Å; R299-S303 PolarHBondContact O-OG 3.24Å; L300-S303 PolarHBondContact O-N 3.04Å; L300-S303 VanDerWaalsContact O-N 3.12Å; L300-S303 PolarHBondContact O-OG 3.2Å; V301-S303 VanDerWaalsContact C-N 3.28Å; V301-S303 PolarHBondContact O-N 2.99Å; S303-G305 PolarHBondContact O-N 3.28Å
304	H	93.1	Very high	89.9	Confident	16 Å²	16	46.6 Å²	46.6	7%	0.074	23%	0.233	C	C	.	.			trans	-73.6	99.6	176.9	-168.1	-119.2	0	0	0	111	L300 V301 Y307 V308 D425 F426 K429	L300-H304 PolarHBondContact O-N 3.5Å; V301-H304 WeakPolarHBondContact O-CB 3.34Å; V301-H304 PolarHBondContact O-N 2.86Å; V301-H304 VanDerWaalsContact O-N 3.12Å; H304-Y307 WeakPolarHBondContact O-CB 3.43Å; H304-Y307 PolarHBondContact O-N 3.01Å; H304-V308 PolarHBondContact O-N 3.18Å; H304-D425 IonicContact CE1-OD2 2.89Å; H304-D425 IonicContact NE2-OD2 3.97Å; H304-D425 PolarHBondContact NE2-OD2 3.08Å; H304-F426 HydrophobicContact CB-CD2 4.09Å; H304-F426 AromaticContact CD2-CD2 3.96Å; H304-F426 AromaticContact CG-CD2 3.88Å; H304-K429 PolarHBondContact NE2-NZ 2.78Å
305	G	92.9	Very high	90.8	Very high	37 Å²	37	46.1 Å²	46.1	38%	0.381	23%	0.233	S	C	.	.	H	α-helix	trans	-49.3	-45.4	-175.9	0	0	0	0	0	116.2	S303 Y307 K309	S303-G305 PolarHBondContact O-N 3.28Å; G305-Y307 VanDerWaalsContact C-N 3.3Å; G305-Y307 PolarHBondContact O-N 3.3Å; G305-K309 VanDerWaalsContact O-CG 3.31Å; G305-K309 WeakPolarHBondContact O-CG 3.13Å; G305-K309 PolarHBondContact O-N 3.35Å
306	P	94.3	Very high	91.5	Very high	12 Å²	12	41 Å²	41	8%	0.078	21%	0.21	C	C	.	.	H	α-helix	trans	-59.5	-37.8	175.6	-24.3	33.5	0	0	0	113.5	L310 Y505 P506 I507	P306-L310 WeakPolarHBondContact O-CB 3.36Å; P306-L310 PolarHBondContact O-N 3.3Å; P306-L310 VanDerWaalsContact O-N 3.11Å; P306-Y505 HydrophobicContact CB-CE2 4.33Å; P306-Y505 WeakPolarHBondContact O-CE2 3.17Å; P306-P506 HydrophobicContact CB-CG 3.98Å; P306-P506 HydrophobicContact CG-CG 3.85Å; P306-I507 HydrophobicContact CB-CD1 3.84Å; P306-I507 HydrophobicContact CB-CG1 4.38Å
307	Y	94.8	Very high	92.1	Very high	0 Å²	0	35.8 Å²	35.8	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-67.2	-50.2	179.5	179.8	-116.5	0	0	0	112	V301 M302 H304 G305 K309 L310 I311 L419 V422 F440 F443	V301-Y307 HydrophobicContact CG1-CD1 3.63Å; V301-Y307 HydrophobicContact CG1-CE1 3.27Å; V301-Y307 HydrophobicContact CG1-CG 4.49Å; V301-Y307 WeakPolarHBondContact O-CD1 3.44Å; M302-Y307 HydrophobicContact SD-CD1 4.28Å; M302-Y307 HydrophobicContact SD-CE1 4.03Å; H304-Y307 WeakPolarHBondContact O-CB 3.43Å; H304-Y307 PolarHBondContact O-N 3.01Å; G305-Y307 VanDerWaalsContact C-N 3.3Å; G305-Y307 PolarHBondContact O-N 3.3Å; Y307-K309 VanDerWaalsContact C-N 3.31Å; Y307-K309 PolarHBondContact O-N 3.44Å; Y307-L310 WeakPolarHBondContact O-CB 3.43Å; Y307-L310 PolarHBondContact O-N 3.25Å; Y307-L310 VanDerWaalsContact O-N 3.13Å; Y307-I311 HydrophobicContact CD1-CD1 4.34Å; Y307-I311 HydrophobicContact CD2-CD1 4.16Å; Y307-I311 HydrophobicContact CD2-CG1 4.49Å; Y307-I311 HydrophobicContact CE1-CD1 3.56Å; Y307-I311 HydrophobicContact CE2-CD1 3.33Å; Y307-I311 HydrophobicContact CE2-CG1 3.99Å; Y307-I311 PolarHBondContact O-N 3.05Å; Y307-I311 WeakPolarHBondContact OH-CD1 3.5Å; Y307-L419 HydrophobicContact CD2-CD1 4.18Å; Y307-L419 HydrophobicContact CE2-CD1 3.66Å; Y307-V422 HydrophobicContact CD2-CG1 4.03Å; Y307-V422 HydrophobicContact CG-CG1 4.29Å; Y307-F440 HydrophobicContact CD1-CD1 4.31Å; Y307-F440 HydrophobicContact CD1-CE1 4.16Å; Y307-F440 AromaticContact CD2-CD1 3.46Å; Y307-F440 HydrophobicContact CD2-CD1 3.46Å; Y307-F440 VanDerWaalsContact CD2-CD1 3.46Å; Y307-F440 AromaticContact CD2-CE1 3.74Å; Y307-F440 HydrophobicContact CD2-CE1 3.74Å; Y307-F440 HydrophobicContact CE1-CD1 4.23Å; Y307-F440 HydrophobicContact CE1-CE1 4.47Å; Y307-F440 HydrophobicContact CE2-CB 4.4Å; Y307-F440 AromaticContact CE2-CD1 3.38Å; Y307-F440 HydrophobicContact CE2-CD1 3.38Å; Y307-F440 HydrophobicContact CE2-CE1 4.09Å; Y307-F440 HydrophobicContact CE2-CG 4.34Å; Y307-F440 AromaticContact CG-CD1 3.9Å; Y307-F440 HydrophobicContact CG-CD1 3.9Å; Y307-F440 AromaticContact CG-CE1 3.73Å; Y307-F440 HydrophobicContact CG-CE1 3.73Å; Y307-F440 AromaticContact CZ-CD1 3.72Å; Y307-F440 PolarHBondContact OH-O 3.28Å; Y307-F443 HydrophobicContact CE1-CD1 4.25Å
308	V	94.4	Very high	92.7	Very high	42 Å²	42	36.7 Å²	36.7	26%	0.255	19%	0.193	S	C	.	.	H	α-helix	trans	-58	-46.3	179.9	179.5	0	0	0	0	110.7	M302 H304 L310 I311 T312	M302-V308 HydrophobicContact CE-CG2 3.93Å; M302-V308 WeakPolarHBondContact O-CG2 3.38Å; M302-V308 HydrophobicContact SD-CG2 4.34Å; H304-V308 PolarHBondContact O-N 3.18Å; V308-L310 VanDerWaalsContact C-N 3.33Å; V308-L310 PolarHBondContact O-N 2.81Å; V308-I311 PolarHBondContact O-N 3.1Å; V308-T312 WeakPolarHBondContact O-CB 3.23Å; V308-T312 PolarHBondContact O-N 3.22Å; V308-T312 PolarHBondContact O-OG1 3.11Å
309	K	94.3	Very high	93.2	Very high	84 Å²	84	36.1 Å²	36.1	37%	0.365	19%	0.189	S	C	.	.	H	α-helix	trans	-60.9	-41.5	177.8	-68.3	172	177.4	-176	0	112.5	G305 Y307 G313 L504	G305-K309 VanDerWaalsContact O-CG 3.31Å; G305-K309 WeakPolarHBondContact O-CG 3.13Å; G305-K309 PolarHBondContact O-N 3.35Å; Y307-K309 VanDerWaalsContact C-N 3.31Å; Y307-K309 PolarHBondContact O-N 3.44Å; K309-G313 PolarHBondContact O-N 3.06Å; K309-G313 VanDerWaalsContact O-N 3.13Å; K309-L504 HydrophobicContact CD-CB 4.36Å; K309-L504 VanDerWaalsContact CD-O 3.3Å; K309-L504 WeakPolarHBondContact CD-O 3.47Å; K309-L504 PolarHBondContact NZ-O 3.45Å
310	L	94.7	Very high	93.6	Very high	2 Å²	2	26.4 Å²	26.4	1%	0.01	15%	0.153	C	C	.	.	H	α-helix	trans	-64.4	-49.4	178.2	-171.5	71.1	0	0	0	110.9	P306 Y307 V308 G313 F314 M418 V422 F502 Y505	P306-L310 WeakPolarHBondContact O-CB 3.36Å; P306-L310 PolarHBondContact O-N 3.3Å; P306-L310 VanDerWaalsContact O-N 3.11Å; Y307-L310 WeakPolarHBondContact O-CB 3.43Å; Y307-L310 PolarHBondContact O-N 3.25Å; Y307-L310 VanDerWaalsContact O-N 3.13Å; V308-L310 VanDerWaalsContact C-N 3.33Å; V308-L310 PolarHBondContact O-N 2.81Å; L310-G313 PolarHBondContact O-N 2.95Å; L310-F314 HydrophobicContact CD1-CD2 4.08Å; L310-F314 HydrophobicContact CD1-CE2 3.46Å; L310-F314 VanDerWaalsContact CD1-CE2 3.46Å; L310-F314 HydrophobicContact CD1-CZ 4.28Å; L310-F314 HydrophobicContact CD2-CE2 4.17Å; L310-F314 HydrophobicContact CG-CD2 3.83Å; L310-F314 HydrophobicContact CG-CE2 3.61Å; L310-F314 VanDerWaalsContact O-CD2 3.28Å; L310-F314 WeakPolarHBondContact O-CD2 3.15Å; L310-F314 PolarHBondContact O-N 2.89Å; L310-M418 HydrophobicContact CD1-CB 4.22Å; L310-M418 HydrophobicContact CD1-CE 3.65Å; L310-M418 HydrophobicContact CD1-SD 4.17Å; L310-M418 HydrophobicContact CD2-CB 4.12Å; L310-V422 HydrophobicContact CD2-CG2 3.5Å; L310-V422 VanDerWaalsContact CD2-CG2 3.5Å; L310-F502 HydrophobicContact CD1-CD1 4.43Å; L310-F502 HydrophobicContact CD1-CE1 4.08Å; L310-Y505 HydrophobicContact CB-CD2 4Å; L310-Y505 HydrophobicContact CB-CE2 3.8Å; L310-Y505 HydrophobicContact CD1-CD2 4.09Å; L310-Y505 HydrophobicContact CD1-CE1 4.28Å; L310-Y505 HydrophobicContact CD1-CE2 3.84Å; L310-Y505 HydrophobicContact CD1-CG 4.42Å; L310-Y505 HydrophobicContact CD2-CE2 4.42Å; L310-Y505 HydrophobicContact CG-CE2 4.23Å
311	I	94.5	Very high	93.9	Very high	5 Å²	5	26.6 Å²	26.6	3%	0.026	15%	0.152	C	C	.	.	H	α-helix	trans	-65.8	-43	-178.8	-96.3	-177.8	0	0	0	112.3	Y307 V308 G313 F314 L315 F443 Y444 F447	Y307-I311 HydrophobicContact CD1-CD1 4.34Å; Y307-I311 HydrophobicContact CD2-CD1 4.16Å; Y307-I311 HydrophobicContact CD2-CG1 4.49Å; Y307-I311 HydrophobicContact CE1-CD1 3.56Å; Y307-I311 HydrophobicContact CE2-CD1 3.33Å; Y307-I311 HydrophobicContact CE2-CG1 3.99Å; Y307-I311 PolarHBondContact O-N 3.05Å; Y307-I311 WeakPolarHBondContact OH-CD1 3.5Å; V308-I311 PolarHBondContact O-N 3.1Å; I311-G313 VanDerWaalsContact C-N 3.3Å; I311-G313 PolarHBondContact O-N 3.2Å; I311-F314 PolarHBondContact O-N 3.47Å; I311-L315 VanDerWaalsContact O-CB 3.27Å; I311-L315 WeakPolarHBondContact O-CB 3.19Å; I311-L315 PolarHBondContact O-N 2.75Å; I311-F443 HydrophobicContact CD1-CD1 4.48Å; I311-Y444 HydrophobicContact CG1-CD2 4.12Å; I311-F447 HydrophobicContact CD1-CD2 4.01Å; I311-F447 HydrophobicContact CD1-CE2 4.31Å; I311-F447 HydrophobicContact CG2-CD2 3.42Å; I311-F447 VanDerWaalsContact CG2-CD2 3.42Å; I311-F447 HydrophobicContact CG2-CE2 3.43Å; I311-F447 VanDerWaalsContact CG2-CE2 3.43Å; I311-F447 HydrophobicContact CG2-CG 4.17Å; I311-F447 HydrophobicContact CG2-CZ 4.31Å
312	T	94.3	Very high	94.1	Very high	42 Å²	42	28.7 Å²	28.7	26%	0.258	16%	0.163	S	C	.	.	H	α-helix	trans	-65.2	-38.7	178.7	-52.6	0	0	0	0	110.5	V308 L315 F316 L501	V308-T312 WeakPolarHBondContact O-CB 3.23Å; V308-T312 PolarHBondContact O-N 3.22Å; V308-T312 PolarHBondContact O-OG1 3.11Å; T312-L315 PolarHBondContact O-N 2.71Å; T312-F316 HydrophobicContact CG2-CD2 4.01Å; T312-F316 HydrophobicContact CG2-CE2 3.65Å; T312-F316 WeakPolarHBondContact O-CD2 2.99Å; T312-F316 PolarHBondContact O-N 3.46Å; T312-L501 HydrophobicContact CG2-CD1 3.72Å
313	G	95	Very high	94.2	Very high	0 Å²	0	25.9 Å²	25.9	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-58.2	-50.3	172.3	0	0	0	0	0	112	K309 L310 I311 L315 F316 T317 F502	K309-G313 PolarHBondContact O-N 3.06Å; K309-G313 VanDerWaalsContact O-N 3.13Å; L310-G313 PolarHBondContact O-N 2.95Å; I311-G313 VanDerWaalsContact C-N 3.3Å; I311-G313 PolarHBondContact O-N 3.2Å; G313-L315 PolarHBondContact O-N 3.47Å; G313-F316 PolarHBondContact O-N 3.39Å; G313-T317 PolarHBondContact O-N 2.86Å; G313-T317 PolarHBondContact O-OG1 3.2Å; G313-F502 VanDerWaalsContact C-CZ 3.5Å
314	F	94.8	Very high	94.3	Very high	4 Å²	4	23.3 Å²	23.3	2%	0.018	13%	0.13	C	C	.	.	H	α-helix	trans	-66.6	-35.7	177.9	-75.6	-54.7	0	0	0	113.4	L310 I311 F316 T317 S318 L414 P415 M418 Y444 F502	L310-F314 HydrophobicContact CD1-CD2 4.08Å; L310-F314 HydrophobicContact CD1-CE2 3.46Å; L310-F314 VanDerWaalsContact CD1-CE2 3.46Å; L310-F314 HydrophobicContact CD1-CZ 4.28Å; L310-F314 HydrophobicContact CD2-CE2 4.17Å; L310-F314 HydrophobicContact CG-CD2 3.83Å; L310-F314 HydrophobicContact CG-CE2 3.61Å; L310-F314 VanDerWaalsContact O-CD2 3.28Å; L310-F314 WeakPolarHBondContact O-CD2 3.15Å; L310-F314 PolarHBondContact O-N 2.89Å; I311-F314 PolarHBondContact O-N 3.47Å; F314-F316 PolarHBondContact O-N 3.49Å; F314-T317 WeakPolarHBondContact CA-OG1 3.28Å; F314-T317 PolarHBondContact O-N 3.29Å; F314-T317 PolarHBondContact O-OG1 3.3Å; F314-S318 VanDerWaalsContact O-CB 3.25Å; F314-S318 WeakPolarHBondContact O-CB 3.48Å; F314-S318 PolarHBondContact O-N 3.45Å; F314-S318 PolarHBondContact O-OG 2.72Å; F314-L414 HydrophobicContact CE1-CB 4.3Å; F314-L414 HydrophobicContact CZ-CB 4.36Å; F314-P415 HydrophobicContact CD1-CB 3.95Å; F314-P415 HydrophobicContact CD1-CG 3.55Å; F314-P415 HydrophobicContact CD2-CB 3.93Å; F314-P415 HydrophobicContact CD2-CG 4.44Å; F314-P415 HydrophobicContact CE1-CB 3.94Å; F314-P415 HydrophobicContact CE1-CG 3.54Å; F314-P415 VanDerWaalsContact CE2-CA 3.49Å; F314-P415 HydrophobicContact CE2-CB 3.88Å; F314-P415 HydrophobicContact CE2-CG 4.41Å; F314-P415 HydrophobicContact CG-CB 3.98Å; F314-P415 HydrophobicContact CG-CG 4.06Å; F314-P415 HydrophobicContact CZ-CB 3.91Å; F314-P415 HydrophobicContact CZ-CG 4.01Å; F314-M418 HydrophobicContact CE2-CB 4.47Å; F314-M418 HydrophobicContact CE2-SD 4.42Å; F314-M418 HydrophobicContact CZ-SD 3.96Å; F314-Y444 HydrophobicContact CB-CE2 4.22Å; F314-F502 HydrophobicContact CD1-CE1 4.18Å; F314-F502 HydrophobicContact CD1-CE2 4.43Å; F314-F502 AromaticContact CD1-CZ 3.48Å; F314-F502 HydrophobicContact CD1-CZ 3.48Å; F314-F502 VanDerWaalsContact CD1-CZ 3.48Å; F314-F502 HydrophobicContact CD2-CE1 4.1Å; F314-F502 HydrophobicContact CD2-CZ 4.18Å; F314-F502 HydrophobicContact CE1-CE1 4.04Å; F314-F502 HydrophobicContact CE1-CE2 4.39Å; F314-F502 AromaticContact CE1-CZ 3.51Å; F314-F502 HydrophobicContact CE1-CZ 3.51Å; F314-F502 AromaticContact CE2-CE1 3.97Å; F314-F502 HydrophobicContact CE2-CE1 3.97Å; F314-F502 HydrophobicContact CE2-CZ 4.23Å; F314-F502 HydrophobicContact CG-CE1 4.18Å; F314-F502 AromaticContact CG-CZ 3.81Å; F314-F502 HydrophobicContact CG-CZ 3.81Å; F314-F502 AromaticContact CZ-CE1 3.92Å; F314-F502 HydrophobicContact CZ-CE1 3.92Å; F314-F502 AromaticContact CZ-CZ 3.89Å; F314-F502 HydrophobicContact CZ-CZ 3.89Å
315	L	95.1	Very high	94.1	Very high	34 Å²	34	26.7 Å²	26.7	18%	0.178	15%	0.146	C	C	.	.	H	α-helix	trans	-56.9	-48.4	176.9	-179.9	74.7	0	0	0	111.1	I311 T312 G313 L319 F447 F450 A451	I311-L315 VanDerWaalsContact O-CB 3.27Å; I311-L315 WeakPolarHBondContact O-CB 3.19Å; I311-L315 PolarHBondContact O-N 2.75Å; T312-L315 PolarHBondContact O-N 2.71Å; G313-L315 PolarHBondContact O-N 3.47Å; L315-L319 VanDerWaalsContact O-CB 3.29Å; L315-L319 WeakPolarHBondContact O-CB 3.46Å; L315-L319 PolarHBondContact O-N 2.68Å; L315-F447 HydrophobicContact CD1-CB 3.94Å; L315-F447 HydrophobicContact CD1-CD1 4.07Å; L315-F447 HydrophobicContact CD1-CG 4.36Å; L315-F447 VanDerWaalsContact CD1-O 3.25Å; L315-F447 WeakPolarHBondContact CD1-O 3.25Å; L315-F447 HydrophobicContact CD2-CD1 4.5Å; L315-F450 HydrophobicContact CD1-CD1 4.26Å; L315-A451 HydrophobicContact CD1-CB 3.86Å
316	F	96.1	Very high	93.6	Very high	56 Å²	56	27.5 Å²	27.5	25%	0.246	15%	0.154	C	C	.	.	H	α-helix	trans	-65.9	-41.8	178.2	-77	-65.6	0	0	0	112.4	T312 G313 F314 L319 A320 L494 L497 L501	T312-F316 HydrophobicContact CG2-CD2 4.01Å; T312-F316 HydrophobicContact CG2-CE2 3.65Å; T312-F316 WeakPolarHBondContact O-CD2 2.99Å; T312-F316 PolarHBondContact O-N 3.46Å; G313-F316 PolarHBondContact O-N 3.39Å; F314-F316 PolarHBondContact O-N 3.49Å; F316-L319 PolarHBondContact O-N 2.96Å; F316-A320 PolarHBondContact O-N 3Å; F316-A320 VanDerWaalsContact O-N 3.09Å; F316-L494 HydrophobicContact CD1-CD2 3.83Å; F316-L494 HydrophobicContact CE1-CD2 4.43Å; F316-L497 HydrophobicContact CD1-CD2 3.76Å; F316-L497 HydrophobicContact CD2-CD2 4.16Å; F316-L497 HydrophobicContact CD2-CG 4.26Å; F316-L497 HydrophobicContact CE1-CD2 3.52Å; F316-L497 HydrophobicContact CE2-CD2 3.94Å; F316-L497 HydrophobicContact CE2-CG 4.32Å; F316-L497 HydrophobicContact CG-CD2 4.08Å; F316-L497 HydrophobicContact CG-CG 4.36Å; F316-L497 HydrophobicContact CZ-CD2 3.62Å; F316-L497 HydrophobicContact CZ-CG 4.48Å; F316-L501 HydrophobicContact CD2-CD1 3.51Å; F316-L501 HydrophobicContact CE2-CD1 3.76Å
317	T	95.2	Very high	93.4	Very high	3 Å²	3	27 Å²	27	2%	0.018	15%	0.15	C	C	.	.	H	α-helix	trans	-67.9	-41.8	177.4	55.9	0	0	0	0	111.9	G313 F314 A320 F321 I377 F502	G313-T317 PolarHBondContact O-N 2.86Å; G313-T317 PolarHBondContact O-OG1 3.2Å; F314-T317 WeakPolarHBondContact CA-OG1 3.28Å; F314-T317 PolarHBondContact O-N 3.29Å; F314-T317 PolarHBondContact O-OG1 3.3Å; T317-A320 VanDerWaalsContact O-CB 3.31Å; T317-A320 WeakPolarHBondContact O-CB 3.39Å; T317-A320 PolarHBondContact O-N 3.45Å; T317-F321 VanDerWaalsContact O-CD2 3.22Å; T317-F321 WeakPolarHBondContact O-CD2 3.34Å; T317-F321 PolarHBondContact O-N 3.34Å; T317-I377 HydrophobicContact CG2-CD1 4.03Å; T317-I377 HydrophobicContact CG2-CG2 3.9Å; T317-F502 HydrophobicContact CG2-CE2 4.07Å
318	S	94.3	Very high	93	Very high	20 Å²	20	28.4 Å²	28.4	14%	0.14	16%	0.156	C	C	.	.	H	α-helix	trans	-64	-41.9	176.6	-65.7	0	0	0	0	111	F314 A320 F321 M322	F314-S318 VanDerWaalsContact O-CB 3.25Å; F314-S318 WeakPolarHBondContact O-CB 3.48Å; F314-S318 PolarHBondContact O-N 3.45Å; F314-S318 PolarHBondContact O-OG 2.72Å; S318-A320 VanDerWaalsContact C-N 3.27Å; S318-A320 PolarHBondContact O-N 3.45Å; S318-F321 PolarHBondContact O-N 3.37Å; S318-M322 WeakPolarHBondContact O-CB 3.34Å; S318-M322 WeakPolarHBondContact O-CG 3.29Å; S318-M322 PolarHBondContact O-N 3.2Å
319	L	95.4	Very high	92.5	Very high	21 Å²	21	29 Å²	29	11%	0.11	16%	0.16	C	C	.	.	H	α-helix	trans	-57.7	-40.9	173.6	-179.3	63.2	0	0	0	111.6	L315 F316 M322 L323 A451 V454 L494	L315-L319 VanDerWaalsContact O-CB 3.29Å; L315-L319 WeakPolarHBondContact O-CB 3.46Å; L315-L319 PolarHBondContact O-N 2.68Å; F316-L319 PolarHBondContact O-N 2.96Å; L319-M322 PolarHBondContact O-N 3.07Å; L319-L323 WeakPolarHBondContact O-CG 3.41Å; L319-L323 PolarHBondContact O-N 2.84Å; L319-A451 HydrophobicContact CB-CB 4.11Å; L319-A451 WeakPolarHBondContact CD1-O 3.43Å; L319-V454 HydrophobicContact CD1-CB 4.15Å; L319-V454 HydrophobicContact CD1-CG1 3.95Å; L319-V454 HydrophobicContact CD2-CG1 4.45Å; L319-L494 HydrophobicContact CB-CD1 4.46Å; L319-L494 HydrophobicContact CD2-CD1 4.03Å; L319-L494 HydrophobicContact CD2-CD2 4.09Å; L319-L494 HydrophobicContact CG-CD1 3.92Å
320	A	95.7	Very high	92	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-61.8	-50.3	176.1	0	0	0	0	0	112.3	F316 T317 S318 L323 V324 P491 L494 I495	F316-A320 PolarHBondContact O-N 3Å; F316-A320 VanDerWaalsContact O-N 3.09Å; T317-A320 VanDerWaalsContact O-CB 3.31Å; T317-A320 WeakPolarHBondContact O-CB 3.39Å; T317-A320 PolarHBondContact O-N 3.45Å; S318-A320 VanDerWaalsContact C-N 3.27Å; S318-A320 PolarHBondContact O-N 3.45Å; A320-L323 PolarHBondContact O-N 2.91Å; A320-V324 WeakPolarHBondContact O-CG2 3.41Å; A320-V324 PolarHBondContact O-N 2.93Å; A320-P491 HydrophobicContact CB-CB 4.01Å; A320-L494 HydrophobicContact CB-CB 3.76Å; A320-L494 HydrophobicContact CB-CD1 4.28Å; A320-I495 HydrophobicContact CB-CD1 4.17Å; A320-I495 HydrophobicContact CB-CG1 3.7Å
321	F	93.4	Very high	91.7	Very high	34 Å²	34	26.9 Å²	26.9	15%	0.149	15%	0.153	C	C	.	.	H	α-helix	trans	-64.6	-39.4	178.4	-79	-78.2	0	0	0	112.2	T317 S318 L323 V324 E325 A380 V408 A411	T317-F321 VanDerWaalsContact O-CD2 3.22Å; T317-F321 WeakPolarHBondContact O-CD2 3.34Å; T317-F321 PolarHBondContact O-N 3.34Å; S318-F321 PolarHBondContact O-N 3.37Å; F321-L323 VanDerWaalsContact C-N 3.3Å; F321-L323 PolarHBondContact O-N 3.42Å; F321-V324 PolarHBondContact O-N 3.01Å; F321-E325 WeakPolarHBondContact O-CB 3.41Å; F321-E325 PolarHBondContact O-N 3.05Å; F321-A380 HydrophobicContact CZ-CB 4.05Å; F321-V408 HydrophobicContact CD1-CG2 4.16Å; F321-V408 HydrophobicContact CE1-CG2 3.92Å; F321-A411 HydrophobicContact CD2-CB 3.67Å; F321-A411 HydrophobicContact CE1-CB 4.18Å; F321-A411 HydrophobicContact CE2-CB 3.3Å; F321-A411 HydrophobicContact CG-CB 4.3Å; F321-A411 HydrophobicContact CZ-CB 3.58Å
322	M	92.4	Very high	91.2	Very high	45 Å²	45	26.7 Å²	26.7	22%	0.222	15%	0.151	C	C	.	.	H	α-helix	trans	-66.5	-30.4	177.3	-68	-73.1	137.7	0	0	112.5	S318 L319 G326 S455	S318-M322 WeakPolarHBondContact O-CB 3.34Å; S318-M322 WeakPolarHBondContact O-CG 3.29Å; S318-M322 PolarHBondContact O-N 3.2Å; L319-M322 PolarHBondContact O-N 3.07Å; M322-G326 PolarHBondContact O-N 3.45Å; M322-S455 PolarHBondContact O-OG 3.19Å
323	L	93.4	Very high	90.6	Very high	3 Å²	3	25.6 Å²	25.6	2%	0.016	15%	0.145	C	C	.	.	H	α-helix	trans	-68.9	-43.2	173.1	-83.8	171.2	0	0	0	111.4	L319 A320 F321 N327 S455 I458 L486 P491 L494	L319-L323 WeakPolarHBondContact O-CG 3.41Å; L319-L323 PolarHBondContact O-N 2.84Å; A320-L323 PolarHBondContact O-N 2.91Å; F321-L323 VanDerWaalsContact C-N 3.3Å; F321-L323 PolarHBondContact O-N 3.42Å; L323-N327 WeakPolarHBondContact O-CB 3.43Å; L323-N327 PolarHBondContact O-N 3.2Å; L323-N327 PolarHBondContact O-ND2 3.31Å; L323-S455 WeakPolarHBondContact CA-OG 3.42Å; L323-S455 WeakPolarHBondContact CD2-OG 3.5Å; L323-S455 WeakPolarHBondContact CG-OG 3.18Å; L323-S455 PolarHBondContact N-OG 2.95Å; L323-S455 VanDerWaalsContact N-OG 3.1Å; L323-I458 HydrophobicContact CD2-CB 4.39Å; L323-I458 HydrophobicContact CD2-CG2 4.24Å; L323-L486 HydrophobicContact CD2-CD2 4.34Å; L323-P491 HydrophobicContact CB-CG 4.19Å; L323-L494 HydrophobicContact CD1-CD1 3.7Å
324	V	92.4	Very high	90.1	Very high	30 Å²	30	27.6 Å²	27.6	18%	0.182	15%	0.153	C	C	.	.	H	α-helix	trans	-62.1	-52.9	175.2	176.9	0	0	0	0	110	A320 F321 N327 F328 L384 V487 P491	A320-V324 WeakPolarHBondContact O-CG2 3.41Å; A320-V324 PolarHBondContact O-N 2.93Å; F321-V324 PolarHBondContact O-N 3.01Å; V324-N327 PolarHBondContact O-N 3.48Å; V324-F328 WeakPolarHBondContact O-CA 3.35Å; V324-F328 WeakPolarHBondContact O-CB 3.38Å; V324-F328 PolarHBondContact O-N 3.45Å; V324-L384 HydrophobicContact CG2-CD2 3.91Å; V324-V487 HydrophobicContact CG1-CG1 4.4Å; V324-P491 HydrophobicContact CG2-CB 3.82Å; V324-P491 HydrophobicContact CG2-CG 3.6Å
325	E	88.1	Confident	89.6	Confident	87 Å²	87	28.5 Å²	28.5	41%	0.407	16%	0.158	S	C	.	.	H	α-helix	trans	-58.9	-49.9	-178.4	-174.3	-177.9	165.7	0	0	111.9	F321 N327 F328	F321-E325 WeakPolarHBondContact O-CB 3.41Å; F321-E325 PolarHBondContact O-N 3.05Å; E325-N327 VanDerWaalsContact C-N 3.28Å; E325-N327 PolarHBondContact O-N 2.79Å; E325-F328 WeakPolarHBondContact O-CB 3.3Å; E325-F328 PolarHBondContact O-N 3Å
326	G	83.8	Confident	89.1	Confident	54 Å²	54	27.3 Å²	27.3	56%	0.557	15%	0.152	S	C	*	.	H	α-helix	trans	-65.7	-26.4	-177.3	0	0	0	0	0	114.5	M322	M322-G326 PolarHBondContact O-N 3.45Å
327	N	89.6	Confident	88.2	Confident	0 Å²	0	27.2 Å²	27.2	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-103.9	-3	179.5	-65.5	-84.3	0	0	0	113.4	L323 V324 E325 V329 L330 F331 S459 L483 V487	L323-N327 WeakPolarHBondContact O-CB 3.43Å; L323-N327 PolarHBondContact O-N 3.2Å; L323-N327 PolarHBondContact O-ND2 3.31Å; V324-N327 PolarHBondContact O-N 3.48Å; E325-N327 VanDerWaalsContact C-N 3.28Å; E325-N327 PolarHBondContact O-N 2.79Å; N327-V329 VanDerWaalsContact C-N 3.35Å; N327-V329 PolarHBondContact O-N 2.86Å; N327-L330 PolarHBondContact O-N 3.32Å; N327-F331 WeakPolarHBondContact O-CB 3.49Å; N327-F331 PolarHBondContact O-N 2.67Å; N327-S459 PolarHBondContact ND2-OG 3.18Å; N327-S459 PolarHBondContact OD1-OG 2.8Å; N327-L483 HydrophobicContact CB-CD2 4.39Å; N327-V487 HydrophobicContact CB-CG2 3.67Å
328	F	86.8	Confident	87.3	Confident	30 Å²	30	28.4 Å²	28.4	13%	0.132	17%	0.172	C	C	.	.	H	α-helix	trans	-57.5	-44.8	-172.4	-177.5	-109	0	0	0	112.7	V324 E325 F331 C332 L345 L346 I349	V324-F328 WeakPolarHBondContact O-CA 3.35Å; V324-F328 WeakPolarHBondContact O-CB 3.38Å; V324-F328 PolarHBondContact O-N 3.45Å; E325-F328 WeakPolarHBondContact O-CB 3.3Å; E325-F328 PolarHBondContact O-N 3Å; F328-F331 PolarHBondContact O-N 3.47Å; F328-C332 WeakPolarHBondContact O-CB 3.2Å; F328-C332 PolarHBondContact O-N 2.76Å; F328-C332 PolarHBondContact O-SG 3.35Å; F328-C332 VanDerWaalsContact O-SG 3.38Å; F328-L345 HydrophobicContact CE1-CB 4.32Å; F328-L345 HydrophobicContact CZ-CB 4.04Å; F328-L346 HydrophobicContact CD1-CD1 4.27Å; F328-L346 HydrophobicContact CE1-CB 4.23Å; F328-L346 HydrophobicContact CE1-CD1 4.4Å; F328-I349 HydrophobicContact CE1-CD1 4.24Å; F328-I349 HydrophobicContact CE2-CD1 3.89Å; F328-I349 HydrophobicContact CZ-CD1 3.65Å
329	V	82.8	Confident	86.1	Confident	55 Å²	55	31.8 Å²	31.8	33%	0.333	18%	0.182	S	C	.	.	H	α-helix	trans	-65.2	-44.4	-179.2	179.7	0	0	0	0	111.5	N327 F331 C332 T333 F342	N327-V329 VanDerWaalsContact C-N 3.35Å; N327-V329 PolarHBondContact O-N 2.86Å; V329-F331 VanDerWaalsContact C-N 3.34Å; V329-C332 PolarHBondContact O-N 3.13Å; V329-T333 VanDerWaalsContact O-CB 3.28Å; V329-T333 WeakPolarHBondContact O-CB 3.32Å; V329-T333 PolarHBondContact O-N 3.15Å; V329-T333 PolarHBondContact O-OG1 3Å; V329-F342 HydrophobicContact CB-CD2 4.48Å; V329-F342 HydrophobicContact CG1-CD2 3.94Å; V329-F342 HydrophobicContact CG1-CE2 4Å; V329-F342 HydrophobicContact CG1-CG 4.27Å; V329-F342 HydrophobicContact CG1-CZ 4.38Å; V329-F342 HydrophobicContact CG2-CD2 3.98Å; V329-F342 HydrophobicContact CG2-CE2 4.27Å
330	L	84.4	Confident	85	Confident	37 Å²	37	37.3 Å²	37.3	19%	0.194	21%	0.212	C	C	.	.	H	α-helix	trans	-65.3	-39.8	178.2	-63.7	177	0	0	0	111.2	N327 T333 Y334 L463 Y468 L483	N327-L330 PolarHBondContact O-N 3.32Å; L330-T333 PolarHBondContact O-N 3.45Å; L330-Y334 HydrophobicContact CB-CD2 4.32Å; L330-Y334 HydrophobicContact CD2-CD2 4.15Å; L330-Y334 HydrophobicContact CD2-CE2 3.69Å; L330-Y334 WeakPolarHBondContact O-CB 3.45Å; L330-Y334 WeakPolarHBondContact O-CD2 3.48Å; L330-Y334 PolarHBondContact O-N 2.89Å; L330-L463 HydrophobicContact CD1-CD1 3.6Å; L330-Y468 HydrophobicContact CD2-CE2 4.18Å; L330-Y468 WeakPolarHBondContact CD2-OH 3.39Å; L330-L483 HydrophobicContact CB-CD1 4.17Å; L330-L483 HydrophobicContact CB-CD2 3.69Å; L330-L483 HydrophobicContact CD1-CD2 4.33Å
331	F	88.1	Confident	84.1	Confident	5 Å²	5	40.6 Å²	40.6	2%	0.022	23%	0.227	C	C	.	.	H	α-helix	trans	-62.6	-50.9	175.8	-179.5	-91.7	0	0	0	111.9	N327 F328 V329 T333 T335 L336 V387 L483 N484 V487	N327-F331 WeakPolarHBondContact O-CB 3.49Å; N327-F331 PolarHBondContact O-N 2.67Å; F328-F331 PolarHBondContact O-N 3.47Å; V329-F331 VanDerWaalsContact C-N 3.34Å; F331-T333 VanDerWaalsContact C-N 3.29Å; F331-T333 PolarHBondContact O-N 3.15Å; F331-T335 HydrophobicContact CD2-CG2 4.27Å; F331-T335 HydrophobicContact CE2-CG2 3.89Å; F331-T335 HydrophobicContact CZ-CG2 4.21Å; F331-T335 WeakPolarHBondContact O-CA 3.43Å; F331-T335 WeakPolarHBondContact O-CB 3.17Å; F331-T335 PolarHBondContact O-N 3.39Å; F331-L336 HydrophobicContact CD1-CD1 4.16Å; F331-L336 HydrophobicContact CD1-CG 4.26Å; F331-L336 HydrophobicContact CE1-CD1 3.77Å; F331-L336 HydrophobicContact CE1-CD2 4.22Å; F331-L336 HydrophobicContact CE1-CG 3.82Å; F331-L336 PolarHBondContact O-N 2.8Å; F331-V387 HydrophobicContact CE1-CG1 3.6Å; F331-V387 HydrophobicContact CE2-CG1 4.32Å; F331-V387 HydrophobicContact CZ-CG1 3.42Å; F331-V387 VanDerWaalsContact CZ-CG1 3.42Å; F331-L483 HydrophobicContact CD2-CB 4.47Å; F331-N484 WeakPolarHBondContact CE2-OD1 3.24Å; F331-V487 HydrophobicContact CB-CG2 3.97Å; F331-V487 HydrophobicContact CD2-CB 4.02Å; F331-V487 HydrophobicContact CD2-CG1 4.2Å; F331-V487 HydrophobicContact CD2-CG2 4.01Å; F331-V487 HydrophobicContact CE2-CB 4.38Å; F331-V487 HydrophobicContact CE2-CG1 4.39Å; F331-V487 HydrophobicContact CG-CB 4.42Å; F331-V487 HydrophobicContact CG-CG1 4.28Å; F331-V487 HydrophobicContact CG-CG2 4.13Å
332	C	84.3	Confident	83.4	Confident	0 Å²	0	41.2 Å²	41.2	0%	0	23%	0.23	C	C	.	.	I	π-helix	trans	-59.4	-40.9	176.8	-73	0	0	0	0	112.3	F328 V329 G337 F338 F342	F328-C332 WeakPolarHBondContact O-CB 3.2Å; F328-C332 PolarHBondContact O-N 2.76Å; F328-C332 PolarHBondContact O-SG 3.35Å; F328-C332 VanDerWaalsContact O-SG 3.38Å; V329-C332 PolarHBondContact O-N 3.13Å; C332-G337 PolarHBondContact O-N 2.89Å; C332-G337 VanDerWaalsContact O-N 3.07Å; C332-F338 PolarHBondContact O-N 2.98Å; C332-F342 HydrophobicContact CB-CB 3.95Å
333	T	82.1	Confident	82.6	Confident	19 Å²	19	44 Å²	44	12%	0.117	24%	0.242	C	C	.	.	I	π-helix	trans	-72	-50.9	-176.9	-62.1	0	0	0	0	112.7	V329 L330 F331 R339	V329-T333 VanDerWaalsContact O-CB 3.28Å; V329-T333 WeakPolarHBondContact O-CB 3.32Å; V329-T333 PolarHBondContact O-N 3.15Å; V329-T333 PolarHBondContact O-OG1 3Å; L330-T333 PolarHBondContact O-N 3.45Å; F331-T333 VanDerWaalsContact C-N 3.29Å; F331-T333 PolarHBondContact O-N 3.15Å; T333-R339 HydrophobicContact CG2-CG 3.64Å
334	Y	83.8	Confident	82.2	Confident	42 Å²	42	47.1 Å²	47.1	17%	0.165	26%	0.259	C	S	.	.	I	π-helix	trans	-101.5	-20.8	-168.5	-61.1	-63.4	0	0	0	114.2	L330 Y468 Q475	L330-Y334 HydrophobicContact CB-CD2 4.32Å; L330-Y334 HydrophobicContact CD2-CD2 4.15Å; L330-Y334 HydrophobicContact CD2-CE2 3.69Å; L330-Y334 WeakPolarHBondContact O-CB 3.45Å; L330-Y334 WeakPolarHBondContact O-CD2 3.48Å; L330-Y334 PolarHBondContact O-N 2.89Å; Y334-Y468 HydrophobicContact CD2-CE2 4.31Å; Y334-Y468 AromaticContact CE2-CE2 3.75Å; Y334-Y468 HydrophobicContact CE2-CE2 3.75Å; Y334-Y468 PolarHBondContact OH-OH 3.11Å; Y334-Q475 HydrophobicContact CD1-CB 4.29Å; Y334-Q475 HydrophobicContact CD1-CG 3.34Å; Y334-Q475 HydrophobicContact CD2-CG 4.11Å; Y334-Q475 HydrophobicContact CE1-CG 3.48Å; Y334-Q475 VanDerWaalsContact CE1-CG 3.48Å; Y334-Q475 HydrophobicContact CE2-CG 4.23Å; Y334-Q475 HydrophobicContact CG-CG 3.67Å; Y334-Q475 PolarHBondContact OH-NE2 2.98Å
335	T	84.8	Confident	81.9	Confident	23 Å²	23	45.7 Å²	45.7	14%	0.141	25%	0.25	C	S	.	.	I	π-helix	trans	-98.8	-48.6	178.8	-51.9	0	0	0	0	111.4	F331 K480 N484	F331-T335 HydrophobicContact CD2-CG2 4.27Å; F331-T335 HydrophobicContact CE2-CG2 3.89Å; F331-T335 HydrophobicContact CZ-CG2 4.21Å; F331-T335 WeakPolarHBondContact O-CA 3.43Å; F331-T335 WeakPolarHBondContact O-CB 3.17Å; F331-T335 PolarHBondContact O-N 3.39Å; T335-K480 HydrophobicContact CG2-CG 4.02Å; T335-N484 VanDerWaalsContact CG2-OD1 3.29Å; T335-N484 WeakPolarHBondContact CG2-OD1 3.48Å
336	L	83.3	Confident	81.7	Confident	9 Å²	9	43.3 Å²	43.3	5%	0.047	24%	0.24	C	C	.	.	I	π-helix	trans	-89.2	-22.1	-178.3	-61	179.7	0	0	0	113.7	F331 F338 S392 T397	F331-L336 HydrophobicContact CD1-CD1 4.16Å; F331-L336 HydrophobicContact CD1-CG 4.26Å; F331-L336 HydrophobicContact CE1-CD1 3.77Å; F331-L336 HydrophobicContact CE1-CD2 4.22Å; F331-L336 HydrophobicContact CE1-CG 3.82Å; F331-L336 PolarHBondContact O-N 2.8Å; L336-F338 HydrophobicContact CB-CD2 3.64Å; L336-F338 HydrophobicContact CB-CE2 3.86Å; L336-F338 HydrophobicContact CB-CG 4.37Å; L336-F338 HydrophobicContact CD1-CD2 4.14Å; L336-F338 HydrophobicContact CD1-CE2 4.28Å; L336-S392 WeakPolarHBondContact O-CB 3.2Å; L336-S392 PolarHBondContact O-OG 3.19Å; L336-T397 HydrophobicContact CD1-CG2 3.83Å
337	G	78.8	Confident	81.8	Confident	55 Å²	55	43.9 Å²	43.9	57%	0.567	23%	0.23	S	C	*	.			trans	82.9	12.3	-180	0	0	0	0	0	114.9	C332 R339	C332-G337 PolarHBondContact O-N 2.89Å; C332-G337 VanDerWaalsContact O-N 3.07Å; G337-R339 PolarHBondContact O-N 3.44Å
338	F	76.3	Confident	81.8	Confident	27 Å²	27	44.7 Å²	44.7	12%	0.118	24%	0.237	C	C	.	.			trans	-94.5	68	-176.4	-59.8	-40.6	0	0	0	112.4	C332 L336 N340 E341 L345 L394 T397	C332-F338 PolarHBondContact O-N 2.98Å; L336-F338 HydrophobicContact CB-CD2 3.64Å; L336-F338 HydrophobicContact CB-CE2 3.86Å; L336-F338 HydrophobicContact CB-CG 4.37Å; L336-F338 HydrophobicContact CD1-CD2 4.14Å; L336-F338 HydrophobicContact CD1-CE2 4.28Å; F338-N340 VanDerWaalsContact C-N 3.33Å; F338-N340 PolarHBondContact O-N 3.19Å; F338-E341 HydrophobicContact CB-CB 4.32Å; F338-L345 HydrophobicContact CD2-CD1 4.45Å; F338-L394 HydrophobicContact CD1-CD1 3.86Å; F338-L394 HydrophobicContact CE1-CB 4.25Å; F338-L394 HydrophobicContact CE1-CD1 3.85Å; F338-L394 HydrophobicContact CG-CD1 4.25Å; F338-L394 HydrophobicContact CZ-CB 4.12Å; F338-L394 HydrophobicContact CZ-CD1 4.21Å; F338-T397 HydrophobicContact CD2-CG2 4.5Å; F338-T397 HydrophobicContact CE2-CG2 4.33Å; F338-T397 WeakPolarHBondContact CE2-OG1 3.39Å
339	R	68.8	Low	82	Confident	91 Å²	91	44.1 Å²	44.1	34%	0.343	24%	0.235	S	C	.	.	T	Hydrogen-bonded Turn	trans	-61.5	-32.6	-177.9	-82.8	177.8	-176.4	-99.2	2.1	114.9	T333 G337 F342 G472 C473	T333-R339 HydrophobicContact CG2-CG 3.64Å; G337-R339 PolarHBondContact O-N 3.44Å; R339-F342 WeakPolarHBondContact O-CD1 3.32Å; R339-F342 VanDerWaalsContact O-CE1 3.25Å; R339-F342 WeakPolarHBondContact O-CE1 3.43Å; R339-G472 PolarHBondContact NH2-O 3.23Å; R339-C473 VanDerWaalsContact NH2-C 3.3Å; R339-C473 PolarHBondContact NH2-O 3.45Å
340	N	71.7	Confident	82.4	Confident	138 Å²	138	42.8 Å²	42.8	74%	0.738	23%	0.225	S	C	*	.	T	Hydrogen-bonded Turn	trans	-102.4	-14.3	-173.6	-60.8	-7.6	0	0	0	113.2	F338	F338-N340 VanDerWaalsContact C-N 3.33Å; F338-N340 PolarHBondContact O-N 3.19Å
341	E	77.3	Confident	82.7	Confident	68 Å²	68	44.6 Å²	44.6	32%	0.318	24%	0.235	S	C	.	.	T	Hydrogen-bonded Turn	trans	-104.3	-3.9	-170.4	-65.8	-67.6	152.9	0	0	113.5	F338 Q343 N344 L345 L394 Y398	F338-E341 HydrophobicContact CB-CB 4.32Å; E341-Q343 VanDerWaalsContact C-N 3.26Å; E341-Q343 PolarHBondContact O-N 3.44Å; E341-N344 PolarHBondContact O-N 2.87Å; E341-N344 VanDerWaalsContact O-N 3.15Å; E341-N344 PolarHBondContact OE2-ND2 3.16Å; E341-L345 PolarHBondContact O-N 3.31Å; E341-L394 HydrophobicContact CB-CD1 4.26Å; E341-L394 HydrophobicContact CG-CD1 4Å; E341-Y398 PolarHBondContact OE2-OH 3.48Å; E341-Y398 VanDerWaalsContact OE2-OH 3.13Å
342	F	77.5	Confident	83	Confident	48 Å²	48	45 Å²	45	21%	0.211	24%	0.239	C	C	.	.	H	α-helix	trans	-62.4	-32.4	-176.7	72.3	-91.9	0	0	0	113	V329 C332 R339 L345 L346	V329-F342 HydrophobicContact CB-CD2 4.48Å; V329-F342 HydrophobicContact CG1-CD2 3.94Å; V329-F342 HydrophobicContact CG1-CE2 4Å; V329-F342 HydrophobicContact CG1-CG 4.27Å; V329-F342 HydrophobicContact CG1-CZ 4.38Å; V329-F342 HydrophobicContact CG2-CD2 3.98Å; V329-F342 HydrophobicContact CG2-CE2 4.27Å; C332-F342 HydrophobicContact CB-CB 3.95Å; R339-F342 WeakPolarHBondContact O-CD1 3.32Å; R339-F342 VanDerWaalsContact O-CE1 3.25Å; R339-F342 WeakPolarHBondContact O-CE1 3.43Å; F342-L345 PolarHBondContact O-N 3.04Å; F342-L346 WeakPolarHBondContact O-CB 3.48Å; F342-L346 PolarHBondContact O-N 3.14Å
343	Q	76.4	Confident	83.5	Confident	102 Å²	102	45 Å²	45	48%	0.477	24%	0.239	S	C	.	.	H	α-helix	trans	-64.9	-44.5	176	-66.7	-175.3	-11	0	0	110.9	E341 L345 L346 L347	E341-Q343 VanDerWaalsContact C-N 3.26Å; E341-Q343 PolarHBondContact O-N 3.44Å; Q343-L345 VanDerWaalsContact C-N 3.34Å; Q343-L345 PolarHBondContact O-N 3.36Å; Q343-L346 PolarHBondContact O-N 3.02Å; Q343-L347 VanDerWaalsContact O-CG 3.3Å; Q343-L347 WeakPolarHBondContact O-CG 3.45Å; Q343-L347 PolarHBondContact O-N 3.42Å
344	N	84.5	Confident	84	Confident	70 Å²	70	44.6 Å²	44.6	37%	0.374	24%	0.236	S	C	.	.	H	α-helix	trans	-65.5	-38.3	177.9	-64.8	-21.8	0	0	0	111.7	E341 L347 A348 Y398	E341-N344 PolarHBondContact O-N 2.87Å; E341-N344 VanDerWaalsContact O-N 3.15Å; E341-N344 PolarHBondContact OE2-ND2 3.16Å; N344-L347 PolarHBondContact O-N 3.16Å; N344-A348 WeakPolarHBondContact O-CB 3.5Å; N344-A348 PolarHBondContact O-N 3.46Å; N344-Y398 HydrophobicContact CB-CE1 4.38Å; N344-Y398 WeakPolarHBondContact CB-OH 3.46Å
345	L	86.3	Confident	84.4	Confident	0 Å²	0	50 Å²	50	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-63.7	-44.4	173.4	-74	169.7	0	0	0	112.1	F328 F338 E341 F342 Q343 L347 A348 I349 T397 Y398 A401	F328-L345 HydrophobicContact CE1-CB 4.32Å; F328-L345 HydrophobicContact CZ-CB 4.04Å; F338-L345 HydrophobicContact CD2-CD1 4.45Å; E341-L345 PolarHBondContact O-N 3.31Å; F342-L345 PolarHBondContact O-N 3.04Å; Q343-L345 VanDerWaalsContact C-N 3.34Å; Q343-L345 PolarHBondContact O-N 3.36Å; L345-L347 VanDerWaalsContact C-N 3.34Å; L345-L347 PolarHBondContact O-N 3.23Å; L345-A348 WeakPolarHBondContact O-CB 3.17Å; L345-A348 PolarHBondContact O-N 3.3Å; L345-I349 WeakPolarHBondContact O-CG1 3.36Å; L345-I349 PolarHBondContact O-N 3.33Å; L345-I349 VanDerWaalsContact O-N 3.07Å; L345-T397 HydrophobicContact CD1-CG2 3.76Å; L345-T397 HydrophobicContact CD2-CG2 3.79Å; L345-T397 HydrophobicContact CG-CG2 4.46Å; L345-Y398 HydrophobicContact CD2-CD1 3.77Å; L345-Y398 HydrophobicContact CD2-CD2 3.94Å; L345-Y398 HydrophobicContact CD2-CE1 3.87Å; L345-Y398 HydrophobicContact CD2-CE2 4.03Å; L345-Y398 HydrophobicContact CD2-CG 3.81Å; L345-Y398 HydrophobicContact CG-CE1 4.36Å; L345-Y398 HydrophobicContact CG-CE2 4.49Å; L345-A401 HydrophobicContact CD2-CB 4.12Å
346	L	83.6	Confident	84.9	Confident	37 Å²	37	49.7 Å²	49.7	19%	0.194	26%	0.259	C	S	.	.	H	α-helix	trans	-61.7	-43.7	176.5	-174.3	67.4	0	0	0	111.2	F65 F328 F342 Q343 A348 I349 M350	F65-L346 HydrophobicContact CZ-CD2 4.5Å; F328-L346 HydrophobicContact CD1-CD1 4.27Å; F328-L346 HydrophobicContact CE1-CB 4.23Å; F328-L346 HydrophobicContact CE1-CD1 4.4Å; F342-L346 WeakPolarHBondContact O-CB 3.48Å; F342-L346 PolarHBondContact O-N 3.14Å; Q343-L346 PolarHBondContact O-N 3.02Å; L346-A348 VanDerWaalsContact C-N 3.31Å; L346-A348 PolarHBondContact O-N 3.45Å; L346-I349 PolarHBondContact O-N 3.46Å; L346-M350 HydrophobicContact CD1-CE 4.11Å; L346-M350 WeakPolarHBondContact O-CG 3.17Å; L346-M350 PolarHBondContact O-N 2.86Å
347	L	86.1	Confident	85.4	Confident	65 Å²	65	49.4 Å²	49.4	34%	0.34	26%	0.257	S	S	.	.	H	α-helix	trans	-59.6	-41.3	174.4	-72	172.1	0	0	0	111.7	V208 Q343 N344 L345 I349 M350 L351	V208-L347 HydrophobicContact CG1-CD2 3.78Å; Q343-L347 VanDerWaalsContact O-CG 3.3Å; Q343-L347 WeakPolarHBondContact O-CG 3.45Å; Q343-L347 PolarHBondContact O-N 3.42Å; N344-L347 PolarHBondContact O-N 3.16Å; L345-L347 VanDerWaalsContact C-N 3.34Å; L345-L347 PolarHBondContact O-N 3.23Å; L347-I349 VanDerWaalsContact C-N 3.34Å; L347-I349 PolarHBondContact O-N 3.35Å; L347-M350 PolarHBondContact O-N 2.87Å; L347-L351 WeakPolarHBondContact O-CB 3.49Å; L347-L351 VanDerWaalsContact O-CG 3.28Å; L347-L351 WeakPolarHBondContact O-CG 3.34Å; L347-L351 PolarHBondContact O-N 2.98Å
348	A	90.8	Very high	86.1	Confident	18 Å²	18	50.4 Å²	50.4	15%	0.149	25%	0.254	C	S	.	.	H	α-helix	trans	-61.2	-40.8	176.1	0	0	0	0	0	112.3	N344 L345 L346 S352 Y398 V402	N344-A348 WeakPolarHBondContact O-CB 3.5Å; N344-A348 PolarHBondContact O-N 3.46Å; L345-A348 WeakPolarHBondContact O-CB 3.17Å; L345-A348 PolarHBondContact O-N 3.3Å; L346-A348 VanDerWaalsContact C-N 3.31Å; L346-A348 PolarHBondContact O-N 3.45Å; A348-S352 VanDerWaalsContact O-CB 3.26Å; A348-S352 WeakPolarHBondContact O-CB 3.45Å; A348-S352 PolarHBondContact O-N 2.94Å; A348-S352 PolarHBondContact O-OG 2.9Å; A348-Y398 HydrophobicContact CB-CD1 4.12Å; A348-Y398 HydrophobicContact CB-CE1 4.31Å; A348-V402 HydrophobicContact CB-CG2 4.37Å
349	I	91	Very high	86.9	Confident	17 Å²	17	54 Å²	54	9%	0.087	27%	0.273	C	S	.	.	H	α-helix	trans	-63.8	-47.6	175.4	-61.5	168.6	0	0	0	110.6	F328 L345 L346 L347 S352 A353 A401 V408	F328-I349 HydrophobicContact CE1-CD1 4.24Å; F328-I349 HydrophobicContact CE2-CD1 3.89Å; F328-I349 HydrophobicContact CZ-CD1 3.65Å; L345-I349 WeakPolarHBondContact O-CG1 3.36Å; L345-I349 PolarHBondContact O-N 3.33Å; L345-I349 VanDerWaalsContact O-N 3.07Å; L346-I349 PolarHBondContact O-N 3.46Å; L347-I349 VanDerWaalsContact C-N 3.34Å; L347-I349 PolarHBondContact O-N 3.35Å; I349-S352 WeakPolarHBondContact CA-OG 3.35Å; I349-S352 PolarHBondContact O-OG 3.24Å; I349-A353 VanDerWaalsContact O-CB 3.31Å; I349-A353 WeakPolarHBondContact O-CB 3.46Å; I349-A353 PolarHBondContact O-N 2.88Å; I349-A401 HydrophobicContact CD1-CB 4.32Å; I349-A401 HydrophobicContact CG1-CB 3.75Å; I349-A401 WeakPolarHBondContact CG1-O 3.14Å; I349-V408 HydrophobicContact CG2-CG2 4.28Å
350	M	89.7	Confident	88.2	Confident	27 Å²	27	50.5 Å²	50.5	13%	0.133	26%	0.26	C	S	.	.	H	α-helix	trans	-69.7	-39.8	-175.8	-64.4	-59.9	136.5	0	0	112.7	V204 V208 L346 L347 A353 T354	V204-M350 HydrophobicContact CG1-CB 4.25Å; V204-M350 WeakPolarHBondContact CG1-O 3.36Å; V204-M350 HydrophobicContact CG1-SD 4.33Å; V208-M350 HydrophobicContact CG2-CB 3.58Å; V208-M350 HydrophobicContact CG2-CG 4.35Å; L346-M350 HydrophobicContact CD1-CE 4.11Å; L346-M350 WeakPolarHBondContact O-CG 3.17Å; L346-M350 PolarHBondContact O-N 2.86Å; L347-M350 PolarHBondContact O-N 2.87Å; M350-A353 PolarHBondContact O-N 3.34Å; M350-T354 PolarHBondContact O-N 3.41Å; M350-T354 PolarHBondContact O-OG1 2.9Å
351	L	91.6	Very high	89.2	Confident	75 Å²	75	45 Å²	45	39%	0.393	23%	0.23	S	C	.	.	H	α-helix	trans	-66.5	-46.1	175.7	-70.8	173.5	0	0	0	111.2	L347 A353 T354 F355	L347-L351 WeakPolarHBondContact O-CB 3.49Å; L347-L351 VanDerWaalsContact O-CG 3.28Å; L347-L351 WeakPolarHBondContact O-CG 3.34Å; L347-L351 PolarHBondContact O-N 2.98Å; L351-A353 VanDerWaalsContact C-N 3.32Å; L351-A353 PolarHBondContact O-N 3.24Å; L351-T354 WeakPolarHBondContact O-CB 3.47Å; L351-T354 PolarHBondContact O-N 3.27Å; L351-F355 WeakPolarHBondContact O-CD2 3.46Å; L351-F355 PolarHBondContact O-N 3.1Å
352	S	94.8	Very high	90	Very high	14 Å²	14	48.1 Å²	48.1	10%	0.098	24%	0.239	C	C	.	.	H	α-helix	trans	-62.9	-38.3	176.5	57.1	0	0	0	0	112.2	A348 I349 F355 T356 V402 G405	A348-S352 VanDerWaalsContact O-CB 3.26Å; A348-S352 WeakPolarHBondContact O-CB 3.45Å; A348-S352 PolarHBondContact O-N 2.94Å; A348-S352 PolarHBondContact O-OG 2.9Å; I349-S352 WeakPolarHBondContact CA-OG 3.35Å; I349-S352 PolarHBondContact O-OG 3.24Å; S352-F355 PolarHBondContact O-N 3.27Å; S352-T356 WeakPolarHBondContact O-CB 3.47Å; S352-T356 PolarHBondContact O-N 3.44Å; S352-T356 VanDerWaalsContact O-N 3.11Å; S352-T356 PolarHBondContact O-OG1 3.41Å; S352-V402 PolarHBondContact OG-O 3.04Å; S352-G405 WeakPolarHBondContact OG-CA 3.19Å
353	A	93.6	Very high	90.7	Very high	0 Å²	0	47.4 Å²	47.4	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-59.6	-47.3	171.8	0	0	0	0	0	111.6	I349 M350 L351 F355 T356 I357 G405 V408 A409	I349-A353 VanDerWaalsContact O-CB 3.31Å; I349-A353 WeakPolarHBondContact O-CB 3.46Å; I349-A353 PolarHBondContact O-N 2.88Å; M350-A353 PolarHBondContact O-N 3.34Å; L351-A353 VanDerWaalsContact C-N 3.32Å; L351-A353 PolarHBondContact O-N 3.24Å; A353-F355 PolarHBondContact O-N 3Å; A353-T356 PolarHBondContact O-N 2.82Å; A353-I357 WeakPolarHBondContact O-CG1 3.37Å; A353-I357 PolarHBondContact O-N 2.97Å; A353-I357 VanDerWaalsContact O-N 3.09Å; A353-G405 WeakPolarHBondContact CA-O 3.42Å; A353-G405 WeakPolarHBondContact CB-O 3.41Å; A353-V408 HydrophobicContact CB-CG1 4.32Å; A353-A409 HydrophobicContact CB-CB 4.16Å; A353-A409 WeakPolarHBondContact O-CB 3.49Å
354	T	92.5	Very high	91.4	Very high	11 Å²	11	42.8 Å²	42.8	7%	0.067	21%	0.214	C	C	.	.	H	α-helix	trans	-55.8	-48.6	178.2	-56.3	0	0	0	0	112.1	T201 V204 L205 M350 L351 T356 I357 P358	T201-T354 HydrophobicContact CG2-CG2 3.71Å; V204-T354 WeakPolarHBondContact CG1-OG1 2.99Å; L205-T354 HydrophobicContact CD1-CG2 4.21Å; L205-T354 HydrophobicContact CD2-CG2 3.94Å; L205-T354 HydrophobicContact CG-CG2 3.82Å; M350-T354 PolarHBondContact O-N 3.41Å; M350-T354 PolarHBondContact O-OG1 2.9Å; L351-T354 WeakPolarHBondContact O-CB 3.47Å; L351-T354 PolarHBondContact O-N 3.27Å; T354-T356 PolarHBondContact O-N 2.99Å; T354-I357 PolarHBondContact O-N 3.2Å; T354-P358 WeakPolarHBondContact O-CD 3.49Å
355	F	93.6	Very high	91.6	Very high	155 Å²	155	43.4 Å²	43.4	68%	0.68	22%	0.221	S	C	*	.	H	α-helix	trans	-67.6	-23.7	178.9	-72.8	-64.8	0	0	0	113.4	L351 S352 A353	L351-F355 WeakPolarHBondContact O-CD2 3.46Å; L351-F355 PolarHBondContact O-N 3.1Å; S352-F355 PolarHBondContact O-N 3.27Å; A353-F355 PolarHBondContact O-N 3Å
356	T	95.1	Very high	91.8	Very high	17 Å²	17	51.5 Å²	51.5	10%	0.104	25%	0.251	C	S	.	.	H	α-helix	trans	-89.1	-18.6	-177.8	-48.6	0	0	0	0	113.1	S352 A353 T354 I359 W360 I406	S352-T356 WeakPolarHBondContact O-CB 3.47Å; S352-T356 PolarHBondContact O-N 3.44Å; S352-T356 VanDerWaalsContact O-N 3.11Å; S352-T356 PolarHBondContact O-OG1 3.41Å; A353-T356 PolarHBondContact O-N 2.82Å; T354-T356 PolarHBondContact O-N 2.99Å; T356-I359 HydrophobicContact CG2-CB 4.32Å; T356-I359 HydrophobicContact CG2-CD1 4.44Å; T356-I359 WeakPolarHBondContact O-CA 3.5Å; T356-I359 WeakPolarHBondContact O-CB 3.35Å; T356-I359 PolarHBondContact O-N 3.02Å; T356-W360 PolarHBondContact O-N 2.83Å; T356-I406 HydrophobicContact CG2-CB 4.23Å; T356-I406 HydrophobicContact CG2-CG1 4.14Å; T356-I406 HydrophobicContact CG2-CG2 4.03Å
357	I	94.3	Very high	92.1	Very high	2 Å²	2	54.6 Å²	54.6	1%	0.01	26%	0.263	C	S	.	.	H	α-helix	trans	-54.9	-46.9	177.4	-71.1	163.7	0	0	0	112.7	A197 M200 T201 V204 A353 T354 I359 W360 Q361 A409 L413	A197-I357 HydrophobicContact CB-CG2 4.17Å; A197-I357 WeakPolarHBondContact O-CG2 3.27Å; M200-I357 HydrophobicContact CB-CD1 4.02Å; M200-I357 HydrophobicContact CB-CG2 4.42Å; T201-I357 WeakPolarHBondContact OG1-CG2 3.23Å; V204-I357 HydrophobicContact CG2-CD1 4.13Å; A353-I357 WeakPolarHBondContact O-CG1 3.37Å; A353-I357 PolarHBondContact O-N 2.97Å; A353-I357 VanDerWaalsContact O-N 3.09Å; T354-I357 PolarHBondContact O-N 3.2Å; I357-I359 VanDerWaalsContact C-N 3.26Å; I357-I359 PolarHBondContact O-N 3.36Å; I357-W360 PolarHBondContact O-N 3.29Å; I357-Q361 PolarHBondContact O-N 2.99Å; I357-A409 HydrophobicContact CG1-CB 3.95Å; I357-L413 HydrophobicContact CG2-CD1 4.39Å; I357-L413 HydrophobicContact CG2-CD2 4.39Å
358	P	92.1	Very high	92.4	Very high	76 Å²	76	51.8 Å²	51.8	49%	0.494	25%	0.25	S	C	.	.	H	α-helix	trans	-61.3	-33.8	175.9	-24.4	34.5	0	0	0	113.5	T354 Q361 W362	T354-P358 WeakPolarHBondContact O-CD 3.49Å; P358-Q361 PolarHBondContact O-N 3.45Å; P358-W362 PolarHBondContact O-N 3.14Å
359	I	94.4	Very high	92.4	Very high	102 Å²	102	51.2 Å²	51.2	52%	0.523	24%	0.244	S	C	.	.	H	α-helix	trans	-66.5	-45	177.1	-59.2	174.5	0	0	0	109.5	T356 I357 Q361 W362 F363	T356-I359 HydrophobicContact CG2-CB 4.32Å; T356-I359 HydrophobicContact CG2-CD1 4.44Å; T356-I359 WeakPolarHBondContact O-CA 3.5Å; T356-I359 WeakPolarHBondContact O-CB 3.35Å; T356-I359 PolarHBondContact O-N 3.02Å; I357-I359 VanDerWaalsContact C-N 3.26Å; I357-I359 PolarHBondContact O-N 3.36Å; I359-Q361 VanDerWaalsContact C-N 3.34Å; I359-Q361 PolarHBondContact O-N 2.87Å; I359-W362 PolarHBondContact O-N 3.48Å; I359-F363 WeakPolarHBondContact O-CB 3.39Å; I359-F363 PolarHBondContact O-N 3.37Å
360	W	94.6	Very high	92.4	Very high	19 Å²	19	52.5 Å²	52.5	7%	0.072	25%	0.249	C	C	.	.	H	α-helix	trans	-63.9	-38.7	174.1	-78.3	118.9	0	0	0	112.6	T356 I357 W362 F363 L364 I375 G376 I406 A410 L413	T356-W360 PolarHBondContact O-N 2.83Å; I357-W360 PolarHBondContact O-N 3.29Å; W360-W362 PolarHBondContact O-N 2.89Å; W360-F363 HydrophobicContact CE3-CB 4.16Å; W360-F363 HydrophobicContact CE3-CD1 4.13Å; W360-F363 HydrophobicContact CE3-CG 4.28Å; W360-F363 AromaticContact CZ3-CD1 3.88Å; W360-F363 HydrophobicContact CZ3-CD1 3.88Å; W360-F363 HydrophobicContact CZ3-CE1 4.39Å; W360-F363 HydrophobicContact CZ3-CG 4.21Å; W360-F363 WeakPolarHBondContact O-CB 3.13Å; W360-F363 PolarHBondContact O-N 2.67Å; W360-F363 VanDerWaalsContact O-N 3.17Å; W360-L364 WeakPolarHBondContact O-CB 2.99Å; W360-L364 WeakPolarHBondContact O-CG 3.44Å; W360-L364 PolarHBondContact O-N 3.39Å; W360-I375 HydrophobicContact CH2-CG2 4.11Å; W360-G376 VanDerWaalsContact CZ2-CA 3.42Å; W360-I406 HydrophobicContact CZ2-CG2 3.99Å; W360-I406 PolarHBondContact NE1-O 3.03Å; W360-A410 HydrophobicContact CD2-CB 3.99Å; W360-A410 HydrophobicContact CG-CB 4.37Å; W360-A410 HydrophobicContact CZ2-CB 3.95Å; W360-L413 HydrophobicContact CB-CD2 3.71Å
361	Q	93.5	Very high	92.5	Very high	22 Å²	22	54.1 Å²	54.1	10%	0.103	26%	0.26	C	S	.	.	H	α-helix	trans	-62.1	-43.5	175	-179	58.7	14.6	0	0	112.2	D193 S194 A197 I357 P358 I359 F363 L364 T365 L413	D193-Q361 PolarHBondContact O-NE2 3.06Å; D193-Q361 PolarHBondContact O-OE1 3.29Å; S194-Q361 VanDerWaalsContact N-NE2 3.19Å; A197-Q361 HydrophobicContact CB-CB 3.79Å; A197-Q361 HydrophobicContact CB-CG 3.67Å; I357-Q361 PolarHBondContact O-N 2.99Å; P358-Q361 PolarHBondContact O-N 3.45Å; I359-Q361 VanDerWaalsContact C-N 3.34Å; I359-Q361 PolarHBondContact O-N 2.87Å; Q361-F363 VanDerWaalsContact C-N 3.33Å; Q361-L364 PolarHBondContact O-N 3.13Å; Q361-T365 WeakPolarHBondContact O-CG2 3.39Å; Q361-T365 PolarHBondContact O-N 3.26Å; Q361-T365 PolarHBondContact O-OG1 3.26Å; Q361-L413 HydrophobicContact CB-CD2 4.5Å
362	W	93.3	Very high	92.7	Very high	134 Å²	134	50.5 Å²	50.5	51%	0.508	24%	0.242	S	C	.	.	H	α-helix	trans	-61.6	-42.7	172.2	172.5	86	0	0	0	111.6	P358 I359 W360 L364 T365 R366 F367	P358-W362 PolarHBondContact O-N 3.14Å; I359-W362 PolarHBondContact O-N 3.48Å; W360-W362 PolarHBondContact O-N 2.89Å; W362-L364 PolarHBondContact O-N 3.28Å; W362-T365 PolarHBondContact O-N 2.63Å; W362-T365 PolarHBondContact O-OG1 3.17Å; W362-R366 WeakPolarHBondContact O-CB 3.45Å; W362-R366 PolarHBondContact O-N 3.05Å; W362-F367 HydrophobicContact CH2-CE2 4.19Å; W362-F367 HydrophobicContact CZ3-CE2 4.22Å
363	F	93.9	Very high	92.6	Very high	33 Å²	33	50 Å²	50	15%	0.145	24%	0.237	C	C	.	.	H	α-helix	trans	-62.8	-42.7	178.7	-166.8	-90.7	0	0	0	112.1	I359 W360 Q361 T365 R366 F367 T371 A372 I375	I359-F363 WeakPolarHBondContact O-CB 3.39Å; I359-F363 PolarHBondContact O-N 3.37Å; W360-F363 HydrophobicContact CE3-CB 4.16Å; W360-F363 HydrophobicContact CE3-CD1 4.13Å; W360-F363 HydrophobicContact CE3-CG 4.28Å; W360-F363 AromaticContact CZ3-CD1 3.88Å; W360-F363 HydrophobicContact CZ3-CD1 3.88Å; W360-F363 HydrophobicContact CZ3-CE1 4.39Å; W360-F363 HydrophobicContact CZ3-CG 4.21Å; W360-F363 WeakPolarHBondContact O-CB 3.13Å; W360-F363 PolarHBondContact O-N 2.67Å; W360-F363 VanDerWaalsContact O-N 3.17Å; Q361-F363 VanDerWaalsContact C-N 3.33Å; F363-T365 PolarHBondContact O-N 3.01Å; F363-R366 PolarHBondContact O-N 3.3Å; F363-F367 HydrophobicContact CD1-CB 4.39Å; F363-F367 HydrophobicContact CD1-CD2 4.36Å; F363-F367 AromaticContact CD2-CD2 3.44Å; F363-F367 HydrophobicContact CD2-CD2 3.44Å; F363-F367 VanDerWaalsContact CD2-CD2 3.44Å; F363-F367 AromaticContact CD2-CE2 3.79Å; F363-F367 HydrophobicContact CD2-CE2 3.79Å; F363-F367 HydrophobicContact CD2-CG 4.4Å; F363-F367 HydrophobicContact CE1-CB 3.9Å; F363-F367 HydrophobicContact CE1-CD2 4.23Å; F363-F367 HydrophobicContact CE1-CG 4.34Å; F363-F367 HydrophobicContact CE2-CB 4.37Å; F363-F367 AromaticContact CE2-CD2 3.28Å; F363-F367 HydrophobicContact CE2-CD2 3.28Å; F363-F367 AromaticContact CE2-CE2 3.62Å; F363-F367 HydrophobicContact CE2-CE2 3.62Å; F363-F367 AromaticContact CE2-CG 3.91Å; F363-F367 HydrophobicContact CE2-CG 3.91Å; F363-F367 HydrophobicContact CE2-CZ 4.49Å; F363-F367 AromaticContact CG-CD2 3.98Å; F363-F367 HydrophobicContact CG-CD2 3.98Å; F363-F367 HydrophobicContact CZ-CB 3.86Å; F363-F367 AromaticContact CZ-CD2 3.68Å; F363-F367 HydrophobicContact CZ-CD2 3.68Å; F363-F367 HydrophobicContact CZ-CE2 4.39Å; F363-F367 AromaticContact CZ-CG 3.85Å; F363-F367 HydrophobicContact CZ-CG 3.85Å; F363-F367 PolarHBondContact O-N 3.2Å; F363-T371 HydrophobicContact CE1-CG2 4.36Å; F363-T371 HydrophobicContact CZ-CG2 4.44Å; F363-A372 HydrophobicContact CD1-CB 3.7Å; F363-A372 HydrophobicContact CE1-CB 4.06Å; F363-I375 HydrophobicContact CE1-CD1 3.97Å; F363-I375 HydrophobicContact CE2-CD1 4.49Å; F363-I375 HydrophobicContact CZ-CD1 3.48Å; F363-I375 VanDerWaalsContact CZ-CD1 3.48Å
364	L	90.9	Very high	92.6	Very high	4 Å²	4	53.2 Å²	53.2	2%	0.021	25%	0.25	C	S	.	.	H	α-helix	trans	-58.7	-47.1	178.8	-79.6	167.7	0	0	0	112.6	W360 Q361 W362 R366 G368 K369 A372 L413 L414	W360-L364 WeakPolarHBondContact O-CB 2.99Å; W360-L364 WeakPolarHBondContact O-CG 3.44Å; W360-L364 PolarHBondContact O-N 3.39Å; Q361-L364 PolarHBondContact O-N 3.13Å; W362-L364 PolarHBondContact O-N 3.28Å; L364-R366 VanDerWaalsContact C-N 3.32Å; L364-R366 PolarHBondContact O-N 3.09Å; L364-G368 CarbonylContact O-C 3.54Å; L364-G368 VanDerWaalsContact O-CA 3.23Å; L364-G368 WeakPolarHBondContact O-CA 3.3Å; L364-G368 PolarHBondContact O-N 2.88Å; L364-G368 VanDerWaalsContact O-N 3.1Å; L364-K369 HydrophobicContact CD2-CB 3.74Å; L364-K369 HydrophobicContact CD2-CG 3.77Å; L364-A372 HydrophobicContact CD2-CB 3.32Å; L364-A372 HydrophobicContact CG-CB 3.95Å; L364-L413 HydrophobicContact CD1-CD2 3.56Å; L364-L413 HydrophobicContact CD1-CG 4.02Å; L364-L414 HydrophobicContact CD1-CD2 4.28Å; L364-L414 HydrophobicContact CD2-CD2 3.49Å; L364-L414 VanDerWaalsContact CD2-CD2 3.49Å; L364-L414 HydrophobicContact CG-CD2 4.27Å
365	T	88.7	Confident	92.7	Very high	84 Å²	84	56.5 Å²	56.5	52%	0.515	27%	0.266	S	S	.	.	H	α-helix	trans	-72.2	-25.3	-178.5	56.7	0	0	0	0	113.1	Q361 W362 F363	Q361-T365 WeakPolarHBondContact O-CG2 3.39Å; Q361-T365 PolarHBondContact O-N 3.26Å; Q361-T365 PolarHBondContact O-OG1 3.26Å; W362-T365 PolarHBondContact O-N 2.63Å; W362-T365 PolarHBondContact O-OG1 3.17Å; F363-T365 PolarHBondContact O-N 3.01Å
366	R	90.4	Very high	92.7	Very high	170 Å²	170	49.1 Å²	49.1	64%	0.642	23%	0.234	S	C	*	.	H	α-helix	trans	-93.1	-45.1	-176.8	-173.3	171.1	-175.4	142.2	0.1	114.1	W362 F363 L364	W362-R366 WeakPolarHBondContact O-CB 3.45Å; W362-R366 PolarHBondContact O-N 3.05Å; F363-R366 PolarHBondContact O-N 3.3Å; L364-R366 VanDerWaalsContact C-N 3.32Å; L364-R366 PolarHBondContact O-N 3.09Å
367	F	90.1	Very high	92.6	Very high	102 Å²	102	48.3 Å²	48.3	45%	0.447	23%	0.229	S	C	.	.	H	α-helix	trans	-106.9	-5.6	-173.4	-62.9	-79.9	0	0	0	113.4	W362 F363 T371	W362-F367 HydrophobicContact CH2-CE2 4.19Å; W362-F367 HydrophobicContact CZ3-CE2 4.22Å; F363-F367 HydrophobicContact CD1-CB 4.39Å; F363-F367 HydrophobicContact CD1-CD2 4.36Å; F363-F367 AromaticContact CD2-CD2 3.44Å; F363-F367 HydrophobicContact CD2-CD2 3.44Å; F363-F367 VanDerWaalsContact CD2-CD2 3.44Å; F363-F367 AromaticContact CD2-CE2 3.79Å; F363-F367 HydrophobicContact CD2-CE2 3.79Å; F363-F367 HydrophobicContact CD2-CG 4.4Å; F363-F367 HydrophobicContact CE1-CB 3.9Å; F363-F367 HydrophobicContact CE1-CD2 4.23Å; F363-F367 HydrophobicContact CE1-CG 4.34Å; F363-F367 HydrophobicContact CE2-CB 4.37Å; F363-F367 AromaticContact CE2-CD2 3.28Å; F363-F367 HydrophobicContact CE2-CD2 3.28Å; F363-F367 AromaticContact CE2-CE2 3.62Å; F363-F367 HydrophobicContact CE2-CE2 3.62Å; F363-F367 AromaticContact CE2-CG 3.91Å; F363-F367 HydrophobicContact CE2-CG 3.91Å; F363-F367 HydrophobicContact CE2-CZ 4.49Å; F363-F367 AromaticContact CG-CD2 3.98Å; F363-F367 HydrophobicContact CG-CD2 3.98Å; F363-F367 HydrophobicContact CZ-CB 3.86Å; F363-F367 AromaticContact CZ-CD2 3.68Å; F363-F367 HydrophobicContact CZ-CD2 3.68Å; F363-F367 HydrophobicContact CZ-CE2 4.39Å; F363-F367 AromaticContact CZ-CG 3.85Å; F363-F367 HydrophobicContact CZ-CG 3.85Å; F363-F367 PolarHBondContact O-N 3.2Å; F367-T371 HydrophobicContact CB-CG2 4.34Å; F367-T371 WeakPolarHBondContact O-CB 3.42Å; F367-T371 PolarHBondContact O-OG1 3.28Å
368	G	91.1	Very high	92.6	Very high	5 Å²	5	50.6 Å²	50.6	5%	0.052	25%	0.245	C	C	.	.			trans	86.2	152.6	179.1	0	0	0	0	0	113.7	L364 K370 T371 A372 E509	L364-G368 CarbonylContact O-C 3.54Å; L364-G368 VanDerWaalsContact O-CA 3.23Å; L364-G368 WeakPolarHBondContact O-CA 3.3Å; L364-G368 PolarHBondContact O-N 2.88Å; L364-G368 VanDerWaalsContact O-N 3.1Å; G368-K370 PolarHBondContact O-N 3.47Å; G368-T371 PolarHBondContact O-N 2.94Å; G368-A372 PolarHBondContact O-N 2.94Å; G368-A372 VanDerWaalsContact O-N 3.12Å; G368-E509 WeakPolarHBondContact CA-OE2 3.44Å
369	K	91.4	Very high	92.7	Very high	7 Å²	7	48.1 Å²	48.1	3%	0.03	23%	0.23	C	C	.	.	H	α-helix	trans	-64.5	-34.7	-172.9	-41.2	-177.1	-171.1	173.5	0	115.7	D193 L364 A372 V373 S417 M418 D421 R512	D193-K369 VanDerWaalsContact CG-NZ 3.32Å; D193-K369 WeakPolarHBondContact OD1-CE 3.45Å; D193-K369 IonicContact OD1-NZ 2.68Å; D193-K369 PolarHBondContact OD1-NZ 3.35Å; D193-K369 WeakPolarHBondContact OD2-CE 3.43Å; D193-K369 IonicContact OD2-NZ 3.08Å; D193-K369 PolarHBondContact OD2-NZ 3.38Å; L364-K369 HydrophobicContact CD2-CB 3.74Å; L364-K369 HydrophobicContact CD2-CG 3.77Å; K369-A372 WeakPolarHBondContact O-CB 3.18Å; K369-A372 PolarHBondContact O-N 3.37Å; K369-V373 WeakPolarHBondContact O-CG2 3.4Å; K369-V373 PolarHBondContact O-N 2.91Å; K369-S417 VanDerWaalsContact CD-OG 3.29Å; K369-S417 WeakPolarHBondContact CD-OG 3.42Å; K369-S417 VanDerWaalsContact CE-OG 3.25Å; K369-S417 WeakPolarHBondContact CE-OG 3.21Å; K369-S417 PolarHBondContact NZ-O 3.16Å; K369-S417 PolarHBondContact NZ-OG 2.91Å; K369-M418 HydrophobicContact CB-CG 4.01Å; K369-M418 HydrophobicContact CB-SD 4.47Å; K369-M418 HydrophobicContact CD-CG 4.07Å; K369-D421 VanDerWaalsContact CD-OD2 3.31Å; K369-D421 WeakPolarHBondContact CD-OD2 3.26Å; K369-D421 VanDerWaalsContact NZ-CG 3.34Å; K369-D421 IonicContact NZ-OD1 2.68Å; K369-D421 PolarHBondContact NZ-OD1 2.91Å; K369-D421 IonicContact NZ-OD2 3.64Å; K369-D421 PolarHBondContact NZ-OD2 3.27Å; K369-D421 VanDerWaalsContact NZ-OD2 3.13Å; K369-R512 VanDerWaalsContact CB-NH1 3.31Å; K369-R512 VanDerWaalsContact CD-NH1 3.25Å
370	K	91.1	Very high	92.6	Very high	43 Å²	43	43.4 Å²	43.4	19%	0.187	21%	0.206	C	C	.	.	H	α-helix	trans	-66.1	-44.6	178.9	-169.5	169.7	-172.9	174.1	0	111.4	G368 A372 V373 Y374 F502 Y505 D508	G368-K370 PolarHBondContact O-N 3.47Å; K370-A372 VanDerWaalsContact C-N 3.3Å; K370-A372 PolarHBondContact O-N 3.31Å; K370-V373 PolarHBondContact O-N 3.38Å; K370-Y374 HydrophobicContact CG-CD2 4.15Å; K370-Y374 HydrophobicContact CG-CE2 3.88Å; K370-Y374 VanDerWaalsContact O-CD2 3.22Å; K370-Y374 WeakPolarHBondContact O-CD2 3.23Å; K370-Y374 PolarHBondContact O-N 3.23Å; K370-Y374 VanDerWaalsContact O-N 3.15Å; K370-F502 WeakPolarHBondContact CE-O 3.37Å; K370-Y505 PolarHBondContact NZ-O 3.24Å; K370-D508 WeakPolarHBondContact CD-OD1 3.49Å; K370-D508 VanDerWaalsContact CE-OD1 3.32Å; K370-D508 WeakPolarHBondContact CE-OD1 3.43Å; K370-D508 IonicContact NZ-OD1 2.77Å; K370-D508 PolarHBondContact NZ-OD1 3.29Å; K370-D508 IonicContact NZ-OD2 3.25Å
371	T	92.4	Very high	92.6	Very high	61 Å²	61	44 Å²	44	37%	0.374	21%	0.212	S	C	.	.	H	α-helix	trans	-60.1	-42.3	174.6	-44.9	0	0	0	0	111.2	F363 F367 G368 Y374 I375	F363-T371 HydrophobicContact CE1-CG2 4.36Å; F363-T371 HydrophobicContact CZ-CG2 4.44Å; F367-T371 HydrophobicContact CB-CG2 4.34Å; F367-T371 WeakPolarHBondContact O-CB 3.42Å; F367-T371 PolarHBondContact O-OG1 3.28Å; G368-T371 PolarHBondContact O-N 2.94Å; T371-Y374 PolarHBondContact O-N 3.44Å; T371-I375 HydrophobicContact CG2-CD1 3.77Å; T371-I375 WeakPolarHBondContact O-CG1 3.28Å; T371-I375 PolarHBondContact O-N 2.92Å
372	A	93.9	Very high	92.6	Very high	0 Å²	0	46.4 Å²	46.4	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-62.7	-40.6	176.9	0	0	0	0	0	112.9	F363 L364 G368 K369 K370 G376 L414	F363-A372 HydrophobicContact CD1-CB 3.7Å; F363-A372 HydrophobicContact CE1-CB 4.06Å; L364-A372 HydrophobicContact CD2-CB 3.32Å; L364-A372 HydrophobicContact CG-CB 3.95Å; G368-A372 PolarHBondContact O-N 2.94Å; G368-A372 VanDerWaalsContact O-N 3.12Å; K369-A372 WeakPolarHBondContact O-CB 3.18Å; K369-A372 PolarHBondContact O-N 3.37Å; K370-A372 VanDerWaalsContact C-N 3.3Å; K370-A372 PolarHBondContact O-N 3.31Å; A372-G376 PolarHBondContact O-N 3.45Å; A372-L414 HydrophobicContact CB-CD2 3.84Å
373	V	93.9	Very high	92.4	Very high	2 Å²	2	42.1 Å²	42.1	1%	0.012	21%	0.214	C	C	.	.	H	α-helix	trans	-58.3	-50.9	172.7	172.1	0	0	0	0	111.5	K369 K370 I375 I377 L414 M418 F502	K369-V373 WeakPolarHBondContact O-CG2 3.4Å; K369-V373 PolarHBondContact O-N 2.91Å; K370-V373 PolarHBondContact O-N 3.38Å; V373-I375 PolarHBondContact O-N 3.07Å; V373-I377 HydrophobicContact CG1-CD1 3.86Å; V373-I377 HydrophobicContact CG1-CG1 4.49Å; V373-I377 VanDerWaalsContact O-CB 3.29Å; V373-I377 WeakPolarHBondContact O-CB 3.2Å; V373-I377 WeakPolarHBondContact O-CG1 3.38Å; V373-I377 PolarHBondContact O-N 3.11Å; V373-L414 HydrophobicContact CB-CD1 4.26Å; V373-L414 HydrophobicContact CG2-CB 4.16Å; V373-L414 HydrophobicContact CG2-CD1 3.9Å; V373-L414 HydrophobicContact CG2-CD2 3.91Å; V373-L414 HydrophobicContact CG2-CG 4.23Å; V373-M418 HydrophobicContact CG2-CE 4.35Å; V373-M418 HydrophobicContact CG2-SD 3.3Å; V373-M418 WeakPolarHBondContact CG2-SD 3.47Å; V373-F502 HydrophobicContact CG1-CB 4.32Å; V373-F502 HydrophobicContact CG1-CD1 4.3Å; V373-F502 HydrophobicContact CG1-CD2 3.4Å; V373-F502 VanDerWaalsContact CG1-CD2 3.4Å; V373-F502 HydrophobicContact CG1-CE2 3.69Å; V373-F502 HydrophobicContact CG1-CG 3.76Å; V373-F502 HydrophobicContact CG1-CZ 4.26Å
374	Y	93.8	Very high	92.3	Very high	69 Å²	69	41.4 Å²	41.4	27%	0.271	21%	0.212	S	C	.	.	H	α-helix	trans	-60.8	-49.5	-178.7	-82.6	-72	0	0	0	111.9	K370 T371 S378 L499 F502 K503	K370-Y374 HydrophobicContact CG-CD2 4.15Å; K370-Y374 HydrophobicContact CG-CE2 3.88Å; K370-Y374 VanDerWaalsContact O-CD2 3.22Å; K370-Y374 WeakPolarHBondContact O-CD2 3.23Å; K370-Y374 PolarHBondContact O-N 3.23Å; K370-Y374 VanDerWaalsContact O-N 3.15Å; T371-Y374 PolarHBondContact O-N 3.44Å; Y374-S378 WeakPolarHBondContact O-CB 3.4Å; Y374-S378 PolarHBondContact O-N 2.98Å; Y374-S378 PolarHBondContact O-OG 3.37Å; Y374-L499 HydrophobicContact CD1-CD2 3.95Å; Y374-L499 HydrophobicContact CE1-CB 4.47Å; Y374-L499 HydrophobicContact CE1-CD2 4.36Å; Y374-L499 PolarHBondContact OH-O 3.36Å; Y374-F502 VanDerWaalsContact OH-C 3.26Å; Y374-K503 WeakPolarHBondContact OH-CA 3.23Å; Y374-K503 WeakPolarHBondContact OH-CB 3.35Å; Y374-K503 PolarHBondContact OH-N 3.27Å
375	I	94.8	Very high	92.3	Very high	79 Å²	79	44.1 Å²	44.1	41%	0.405	23%	0.229	S	C	.	.	H	α-helix	trans	-71	-44.5	-175.6	-64.5	169.3	0	0	0	110.8	W360 F363 T371 V373 S378 S379	W360-I375 HydrophobicContact CH2-CG2 4.11Å; F363-I375 HydrophobicContact CE1-CD1 3.97Å; F363-I375 HydrophobicContact CE2-CD1 4.49Å; F363-I375 HydrophobicContact CZ-CD1 3.48Å; F363-I375 VanDerWaalsContact CZ-CD1 3.48Å; T371-I375 HydrophobicContact CG2-CD1 3.77Å; T371-I375 WeakPolarHBondContact O-CG1 3.28Å; T371-I375 PolarHBondContact O-N 2.92Å; V373-I375 PolarHBondContact O-N 3.07Å; I375-S378 PolarHBondContact O-OG 3.45Å; I375-S379 WeakPolarHBondContact O-CB 3.41Å; I375-S379 PolarHBondContact O-N 3.02Å; I375-S379 PolarHBondContact O-OG 3.13Å
376	G	93.6	Very high	92.3	Very high	0 Å²	0	43.7 Å²	43.7	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-74.2	-34	-175.2	0	0	0	0	0	114.8	W360 A372 S379	W360-G376 VanDerWaalsContact CZ2-CA 3.42Å; A372-G376 PolarHBondContact O-N 3.45Å; G376-S379 PolarHBondContact O-OG 3.15Å
377	I	92.9	Very high	92.2	Very high	0 Å²	0	37 Å²	37	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-82.3	-36.8	175.2	-61.2	-175.8	0	0	0	110.5	T317 V373 S379 A380 L414 I495 L499 F502	T317-I377 HydrophobicContact CG2-CD1 4.03Å; T317-I377 HydrophobicContact CG2-CG2 3.9Å; V373-I377 HydrophobicContact CG1-CD1 3.86Å; V373-I377 HydrophobicContact CG1-CG1 4.49Å; V373-I377 VanDerWaalsContact O-CB 3.29Å; V373-I377 WeakPolarHBondContact O-CB 3.2Å; V373-I377 WeakPolarHBondContact O-CG1 3.38Å; V373-I377 PolarHBondContact O-N 3.11Å; I377-S379 VanDerWaalsContact C-N 3.29Å; I377-S379 PolarHBondContact O-N 3.43Å; I377-A380 VanDerWaalsContact O-CB 3.3Å; I377-A380 WeakPolarHBondContact O-CB 3.43Å; I377-A380 PolarHBondContact O-N 3.06Å; I377-L414 HydrophobicContact CD1-CD1 4.47Å; I377-L414 HydrophobicContact CG1-CD1 4.2Å; I377-I495 HydrophobicContact CG2-CG2 3.76Å; I377-L499 HydrophobicContact CB-CD2 3.99Å; I377-L499 HydrophobicContact CG2-CD2 3.98Å; I377-L499 HydrophobicContact CG2-CG 4.19Å; I377-F502 HydrophobicContact CD1-CE2 3.88Å
378	S	94	Very high	91.9	Very high	50 Å²	50	34 Å²	34	35%	0.35	19%	0.194	S	C	.	.	H	α-helix	trans	-67.8	-27	176.5	67.4	0	0	0	0	113.3	Y374 I375 A380 V381 P382	Y374-S378 WeakPolarHBondContact O-CB 3.4Å; Y374-S378 PolarHBondContact O-N 2.98Å; Y374-S378 PolarHBondContact O-OG 3.37Å; I375-S378 PolarHBondContact O-OG 3.45Å; S378-A380 PolarHBondContact O-N 3.05Å; S378-A380 VanDerWaalsContact O-N 3.14Å; S378-V381 WeakPolarHBondContact O-CB 3.38Å; S378-V381 PolarHBondContact O-N 2.94Å; S378-V381 VanDerWaalsContact O-N 3.09Å; S378-P382 VanDerWaalsContact O-CD 3.26Å; S378-P382 WeakPolarHBondContact O-CD 3.38Å
379	S	93.9	Very high	91.7	Very high	24 Å²	24	40 Å²	40	17%	0.168	23%	0.225	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.1	-18.4	174.1	59.4	0	0	0	0	113	I375 G376 I377 V381 P382 F383 S407	I375-S379 WeakPolarHBondContact O-CB 3.41Å; I375-S379 PolarHBondContact O-N 3.02Å; I375-S379 PolarHBondContact O-OG 3.13Å; G376-S379 PolarHBondContact O-OG 3.15Å; I377-S379 VanDerWaalsContact C-N 3.29Å; I377-S379 PolarHBondContact O-N 3.43Å; S379-V381 VanDerWaalsContact C-N 3.35Å; S379-P382 WeakPolarHBondContact O-CD 3.4Å; S379-P382 WeakPolarHBondContact O-CG 3.04Å; S379-F383 WeakPolarHBondContact O-CD2 3.45Å; S379-F383 WeakPolarHBondContact O-CE2 3.26Å; S379-F383 WeakPolarHBondContact O-CG 3.32Å; S379-S407 WeakPolarHBondContact CB-OG 3.41Å; S379-S407 PolarHBondContact O-OG 3.49Å; S379-S407 PolarHBondContact OG-OG 3.48Å
380	A	93.3	Very high	91.1	Very high	4 Å²	4	41.1 Å²	41.1	3%	0.033	23%	0.231	C	C	.	.	H	α-helix	trans	-66.9	-34.8	174	0	0	0	0	0	112.6	F321 I377 S378 F383 L384 S407 I495	F321-A380 HydrophobicContact CZ-CB 4.05Å; I377-A380 VanDerWaalsContact O-CB 3.3Å; I377-A380 WeakPolarHBondContact O-CB 3.43Å; I377-A380 PolarHBondContact O-N 3.06Å; S378-A380 PolarHBondContact O-N 3.05Å; S378-A380 VanDerWaalsContact O-N 3.14Å; A380-F383 PolarHBondContact O-N 2.82Å; A380-L384 WeakPolarHBondContact O-CG 3.36Å; A380-L384 PolarHBondContact O-N 2.95Å; A380-S407 WeakPolarHBondContact CA-OG 3.29Å; A380-S407 PolarHBondContact N-OG 3.27Å; A380-I495 HydrophobicContact CB-CD1 3.91Å
381	V	94	Very high	90.4	Very high	30 Å²	30	47.1 Å²	47.1	18%	0.182	26%	0.259	C	S	.	.	H	α-helix	trans	-58.8	-53.5	-174.8	179	0	0	0	0	113	S378 S379 F383 L384 V385 I492 I495	S378-V381 WeakPolarHBondContact O-CB 3.38Å; S378-V381 PolarHBondContact O-N 2.94Å; S378-V381 VanDerWaalsContact O-N 3.09Å; S379-V381 VanDerWaalsContact C-N 3.35Å; V381-F383 PolarHBondContact O-N 3.43Å; V381-L384 PolarHBondContact O-N 3.29Å; V381-V385 HydrophobicContact CG1-CG2 4.46Å; V381-V385 WeakPolarHBondContact O-CG2 3.42Å; V381-V385 PolarHBondContact O-N 3.4Å; V381-I492 HydrophobicContact CG1-CG2 4.19Å; V381-I495 HydrophobicContact CG2-CG2 3.91Å
382	P	92.5	Very high	89.5	Confident	74 Å²	74	48.2 Å²	48.2	48%	0.481	27%	0.27	S	S	.	.	H	α-helix	trans	-62	-31.7	178.5	24.4	-34.7	0	0	0	112.6	S378 S379 V385 L386	S378-P382 VanDerWaalsContact O-CD 3.26Å; S378-P382 WeakPolarHBondContact O-CD 3.38Å; S379-P382 WeakPolarHBondContact O-CD 3.4Å; S379-P382 WeakPolarHBondContact O-CG 3.04Å; P382-V385 PolarHBondContact O-N 3.37Å; P382-L386 WeakPolarHBondContact O-CB 3.42Å; P382-L386 PolarHBondContact O-N 3.45Å
383	F	89.9	Confident	89.1	Confident	43 Å²	43	51.6 Å²	51.6	19%	0.189	29%	0.287	C	S	.	.	H	α-helix	trans	-68.5	-43.9	176.1	-55.1	-33.1	0	0	0	111.6	S379 A380 V381 V385 L386 V387 A403 S407	S379-F383 WeakPolarHBondContact O-CD2 3.45Å; S379-F383 WeakPolarHBondContact O-CE2 3.26Å; S379-F383 WeakPolarHBondContact O-CG 3.32Å; A380-F383 PolarHBondContact O-N 2.82Å; V381-F383 PolarHBondContact O-N 3.43Å; F383-V385 VanDerWaalsContact C-N 3.32Å; F383-V385 PolarHBondContact O-N 2.97Å; F383-L386 WeakPolarHBondContact O-CB 3.37Å; F383-L386 PolarHBondContact O-N 3.48Å; F383-V387 WeakPolarHBondContact O-CG2 3.31Å; F383-V387 PolarHBondContact O-N 3.46Å; F383-A403 HydrophobicContact CD1-CB 3.85Å; F383-A403 WeakPolarHBondContact CD2-O 3.39Å; F383-A403 HydrophobicContact CE1-CB 3.54Å; F383-A403 HydrophobicContact CE2-CB 4.26Å; F383-A403 WeakPolarHBondContact CE2-O 3.28Å; F383-A403 HydrophobicContact CG-CB 4.37Å; F383-A403 HydrophobicContact CZ-CB 3.76Å; F383-A403 WeakPolarHBondContact CZ-O 3.17Å; F383-S407 WeakPolarHBondContact CD2-OG 3.47Å; F383-S407 VanDerWaalsContact CE2-OG 3.24Å; F383-S407 WeakPolarHBondContact CE2-OG 3.5Å
384	L	91.3	Very high	88.6	Confident	18 Å²	18	54.8 Å²	54.8	9%	0.094	30%	0.304	C	S	.	.	H	α-helix	trans	-65	-36.2	175.9	-66	174.4	0	0	0	112.4	V324 A380 V381 V387 A388 V487 P491 I492 I495	V324-L384 HydrophobicContact CG2-CD2 3.91Å; A380-L384 WeakPolarHBondContact O-CG 3.36Å; A380-L384 PolarHBondContact O-N 2.95Å; V381-L384 PolarHBondContact O-N 3.29Å; L384-V387 PolarHBondContact O-N 3.07Å; L384-A388 PolarHBondContact O-N 3.19Å; L384-A388 VanDerWaalsContact O-N 3.07Å; L384-V487 WeakPolarHBondContact CD2-O 3.35Å; L384-P491 HydrophobicContact CD1-CB 3.9Å; L384-I492 HydrophobicContact CB-CD1 3.94Å; L384-I492 HydrophobicContact CB-CG1 3.82Å; L384-I492 HydrophobicContact CD1-CG1 3.88Å; L384-I495 HydrophobicContact CD1-CD1 3.76Å
385	V	91.5	Very high	88.3	Confident	61 Å²	61	57.4 Å²	57.4	37%	0.37	32%	0.321	S	S	.	.	H	α-helix	trans	-64.8	-43.1	172.2	172.3	0	0	0	0	110.6	V381 P382 F383 V387 A388 L389 I492	V381-V385 HydrophobicContact CG1-CG2 4.46Å; V381-V385 WeakPolarHBondContact O-CG2 3.42Å; V381-V385 PolarHBondContact O-N 3.4Å; P382-V385 PolarHBondContact O-N 3.37Å; F383-V385 VanDerWaalsContact C-N 3.32Å; F383-V385 PolarHBondContact O-N 2.97Å; V385-V387 PolarHBondContact O-N 3.07Å; V385-A388 WeakPolarHBondContact O-CB 3.46Å; V385-A388 PolarHBondContact O-N 2.72Å; V385-A388 VanDerWaalsContact O-N 3.11Å; V385-L389 HydrophobicContact CG1-CD1 4.04Å; V385-L389 WeakPolarHBondContact O-CG 3.21Å; V385-L389 PolarHBondContact O-N 3.39Å; V385-L389 VanDerWaalsContact O-N 3.14Å; V385-I492 HydrophobicContact CG2-CD1 3.83Å
386	L	88.9	Confident	88	Confident	76 Å²	76	57.3 Å²	57.3	40%	0.398	32%	0.321	S	S	.	.	H	α-helix	trans	-63.2	-42.5	177.5	-172.7	58.3	0	0	0	111.3	P382 F383 A388 L389 M390 V400	P382-L386 WeakPolarHBondContact O-CB 3.42Å; P382-L386 PolarHBondContact O-N 3.45Å; F383-L386 WeakPolarHBondContact O-CB 3.37Å; F383-L386 PolarHBondContact O-N 3.48Å; L386-A388 PolarHBondContact O-N 2.89Å; L386-L389 PolarHBondContact O-N 2.69Å; L386-L389 VanDerWaalsContact O-N 3.09Å; L386-M390 HydrophobicContact CG-SD 4.5Å; L386-M390 WeakPolarHBondContact O-CG 3.38Å; L386-M390 PolarHBondContact O-N 2.99Å; L386-V400 HydrophobicContact CD2-CG2 3.3Å; L386-V400 HydrophobicContact CG-CG2 3.74Å
387	V	87.2	Confident	87.8	Confident	29 Å²	29	57.8 Å²	57.8	18%	0.176	32%	0.324	C	S	.	.	H	α-helix	trans	-56.8	-38.1	172	172.1	0	0	0	0	111.8	F331 F383 L384 V385 L389 V400 V487 T488	F331-V387 HydrophobicContact CE1-CG1 3.6Å; F331-V387 HydrophobicContact CE2-CG1 4.32Å; F331-V387 HydrophobicContact CZ-CG1 3.42Å; F331-V387 VanDerWaalsContact CZ-CG1 3.42Å; F383-V387 WeakPolarHBondContact O-CG2 3.31Å; F383-V387 PolarHBondContact O-N 3.46Å; L384-V387 PolarHBondContact O-N 3.07Å; V385-V387 PolarHBondContact O-N 3.07Å; V387-L389 VanDerWaalsContact C-N 3.32Å; V387-L389 PolarHBondContact O-N 3.02Å; V387-V400 HydrophobicContact CG2-CG1 3.59Å; V387-V487 HydrophobicContact CG1-CG1 4.32Å; V387-T488 HydrophobicContact CB-CG2 4.34Å; V387-T488 HydrophobicContact CG1-CG2 3.97Å
388	A	85.5	Confident	87.7	Confident	38 Å²	38	60.7 Å²	60.7	31%	0.314	34%	0.336	S	S	.	.	H	α-helix	trans	-68.7	-29	177.9	0	0	0	0	0	113.7	L384 V385 L386 T488 M489	L384-A388 PolarHBondContact O-N 3.19Å; L384-A388 VanDerWaalsContact O-N 3.07Å; V385-A388 WeakPolarHBondContact O-CB 3.46Å; V385-A388 PolarHBondContact O-N 2.72Å; V385-A388 VanDerWaalsContact O-N 3.11Å; L386-A388 PolarHBondContact O-N 2.89Å; A388-T488 HydrophobicContact CB-CG2 3.8Å; A388-M489 HydrophobicContact CB-CE 4.18Å
389	L	85.7	Confident	87.5	Confident	133 Å²	133	63 Å²	63	70%	0.696	35%	0.347	S	S	*	.	H	α-helix	trans	-93.9	-8.3	-177.9	-63.3	174.9	0	0	0	113.2	V385 L386 V387 E391	V385-L389 HydrophobicContact CG1-CD1 4.04Å; V385-L389 WeakPolarHBondContact O-CG 3.21Å; V385-L389 PolarHBondContact O-N 3.39Å; V385-L389 VanDerWaalsContact O-N 3.14Å; L386-L389 PolarHBondContact O-N 2.69Å; L386-L389 VanDerWaalsContact O-N 3.09Å; V387-L389 VanDerWaalsContact C-N 3.32Å; V387-L389 PolarHBondContact O-N 3.02Å; L389-E391 PolarHBondContact O-N 3.32Å
390	M	79.3	Confident	87.4	Confident	30 Å²	30	62.1 Å²	62.1	15%	0.148	34%	0.341	C	S	.	.			trans	-73.1	128.8	-174.4	-87.8	168.3	66.6	0	0	112.4	L386 I396 T397 V400	L386-M390 HydrophobicContact CG-SD 4.5Å; L386-M390 WeakPolarHBondContact O-CG 3.38Å; L386-M390 PolarHBondContact O-N 2.99Å; M390-I396 HydrophobicContact CE-CG2 4.12Å; M390-I396 HydrophobicContact CG-CG2 4.06Å; M390-I396 HydrophobicContact SD-CG2 4.21Å; M390-T397 HydrophobicContact CE-CG2 3.96Å; M390-T397 WeakPolarHBondContact CE-OG1 3.36Å; M390-V400 HydrophobicContact CE-CG2 4.48Å; M390-V400 HydrophobicContact SD-CB 3.96Å; M390-V400 HydrophobicContact SD-CG1 4.14Å; M390-V400 HydrophobicContact SD-CG2 3.58Å; M390-V400 VanDerWaalsContact SD-CG2 3.58Å
391	E	75.7	Confident	87.2	Confident	169 Å²	169	62.3 Å²	62.3	79%	0.79	34%	0.342	S	S	*	.			trans	-85.1	166.6	161	-63.8	-179	177.1	0	0	110.3	L389 N393	L389-E391 PolarHBondContact O-N 3.32Å; E391-N393 VanDerWaalsContact C-N 3.32Å; E391-N393 PolarHBondContact O-N 2.84Å
392	S	74.6	Confident	87.2	Confident	84 Å²	84	64.3 Å²	64.3	59%	0.587	36%	0.355	S	S	*	.	S	Bend	trans	-64.4	86.3	-177	-174.2	0	0	0	0	111.6	L336	L336-S392 WeakPolarHBondContact O-CB 3.2Å; L336-S392 PolarHBondContact O-OG 3.19Å
393	N	84.6	Confident	87.1	Confident	70 Å²	70	61.9 Å²	61.9	37%	0.374	34%	0.34	S	S	.	.			trans	-133.8	117	173	-173.2	-36.3	0	0	0	110	E391 I395 I396 T397	E391-N393 VanDerWaalsContact C-N 3.32Å; E391-N393 PolarHBondContact O-N 2.84Å; N393-I395 PolarHBondContact O-N 2.86Å; N393-I395 PolarHBondContact OD1-N 3.28Å; N393-I395 VanDerWaalsContact OD1-N 3.1Å; N393-I396 HydrophobicContact CB-CB 4.26Å; N393-I396 HydrophobicContact CB-CD1 3.97Å; N393-I396 HydrophobicContact CB-CG1 4.16Å; N393-T397 PolarHBondContact O-N 3.33Å; N393-T397 VanDerWaalsContact O-N 3.08Å; N393-T397 PolarHBondContact O-OG1 3.44Å
394	L	84.6	Confident	87.2	Confident	69 Å²	69	61 Å²	61	36%	0.361	34%	0.341	S	S	.	.	H	α-helix	trans	-60.8	-46.3	-174.2	-166.7	96.9	0	0	0	112.1	F338 E341 I396 T397 Y398	F338-L394 HydrophobicContact CD1-CD1 3.86Å; F338-L394 HydrophobicContact CE1-CB 4.25Å; F338-L394 HydrophobicContact CE1-CD1 3.85Å; F338-L394 HydrophobicContact CG-CD1 4.25Å; F338-L394 HydrophobicContact CZ-CB 4.12Å; F338-L394 HydrophobicContact CZ-CD1 4.21Å; E341-L394 HydrophobicContact CB-CD1 4.26Å; E341-L394 HydrophobicContact CG-CD1 4Å; L394-I396 PolarHBondContact O-N 2.88Å; L394-T397 WeakPolarHBondContact O-CB 3.48Å; L394-T397 PolarHBondContact O-N 3.18Å; L394-T397 VanDerWaalsContact O-N 3.16Å; L394-Y398 HydrophobicContact CD1-CE2 4.31Å; L394-Y398 HydrophobicContact CD2-CD2 4.29Å; L394-Y398 HydrophobicContact CD2-CE2 3.96Å; L394-Y398 HydrophobicContact CG-CD2 4.04Å; L394-Y398 HydrophobicContact CG-CE2 3.87Å; L394-Y398 WeakPolarHBondContact O-CD2 3.31Å; L394-Y398 PolarHBondContact O-N 3.01Å
395	I	87.6	Confident	87.2	Confident	124 Å²	124	60.1 Å²	60.1	64%	0.636	34%	0.337	S	S	*	.	H	α-helix	trans	-65.3	-45.8	-174.4	-60.9	173.7	0	0	0	110.3	N393 T397 Y398 V399	N393-I395 PolarHBondContact O-N 2.86Å; N393-I395 PolarHBondContact OD1-N 3.28Å; N393-I395 VanDerWaalsContact OD1-N 3.1Å; I395-T397 PolarHBondContact O-N 3.4Å; I395-Y398 PolarHBondContact O-N 3.07Å; I395-V399 WeakPolarHBondContact O-CG2 3.36Å; I395-V399 PolarHBondContact O-N 3.16Å; I395-V399 VanDerWaalsContact O-N 3.08Å
396	I	88.2	Confident	87.3	Confident	78 Å²	78	60.3 Å²	60.3	40%	0.4	34%	0.335	S	S	.	.	H	α-helix	trans	-60.5	-41.5	177.2	-59.8	178.1	0	0	0	109.3	M390 N393 L394 Y398 V399 V400	M390-I396 HydrophobicContact CE-CG2 4.12Å; M390-I396 HydrophobicContact CG-CG2 4.06Å; M390-I396 HydrophobicContact SD-CG2 4.21Å; N393-I396 HydrophobicContact CB-CB 4.26Å; N393-I396 HydrophobicContact CB-CD1 3.97Å; N393-I396 HydrophobicContact CB-CG1 4.16Å; L394-I396 PolarHBondContact O-N 2.88Å; I396-Y398 PolarHBondContact O-N 3.47Å; I396-V399 PolarHBondContact O-N 3.34Å; I396-V399 VanDerWaalsContact O-N 3.16Å; I396-V400 HydrophobicContact CG2-CG2 4.31Å; I396-V400 WeakPolarHBondContact O-CG2 3.42Å; I396-V400 PolarHBondContact O-N 2.84Å
397	T	88.3	Confident	87.5	Confident	10 Å²	10	56.8 Å²	56.8	6%	0.061	32%	0.316	C	S	.	.	H	α-helix	trans	-61.4	-41.5	178.6	-50.1	0	0	0	0	112.9	L336 F338 L345 M390 N393 L394 I395 V400 A401	L336-T397 HydrophobicContact CD1-CG2 3.83Å; F338-T397 HydrophobicContact CD2-CG2 4.5Å; F338-T397 HydrophobicContact CE2-CG2 4.33Å; F338-T397 WeakPolarHBondContact CE2-OG1 3.39Å; L345-T397 HydrophobicContact CD1-CG2 3.76Å; L345-T397 HydrophobicContact CD2-CG2 3.79Å; L345-T397 HydrophobicContact CG-CG2 4.46Å; M390-T397 HydrophobicContact CE-CG2 3.96Å; M390-T397 WeakPolarHBondContact CE-OG1 3.36Å; N393-T397 PolarHBondContact O-N 3.33Å; N393-T397 VanDerWaalsContact O-N 3.08Å; N393-T397 PolarHBondContact O-OG1 3.44Å; L394-T397 WeakPolarHBondContact O-CB 3.48Å; L394-T397 PolarHBondContact O-N 3.18Å; L394-T397 VanDerWaalsContact O-N 3.16Å; I395-T397 PolarHBondContact O-N 3.4Å; T397-V400 PolarHBondContact O-N 3.35Å; T397-A401 VanDerWaalsContact O-CB 3.25Å; T397-A401 WeakPolarHBondContact O-CB 3.28Å; T397-A401 PolarHBondContact O-N 3.42Å
398	Y	90.8	Very high	87.7	Confident	61 Å²	61	56.3 Å²	56.3	24%	0.239	31%	0.314	C	S	.	.	H	α-helix	trans	-64.1	-41.5	173.7	-87.6	-78.3	0	0	0	112.8	E341 N344 L345 A348 L394 I395 I396 V400 A401 V402	E341-Y398 PolarHBondContact OE2-OH 3.48Å; E341-Y398 VanDerWaalsContact OE2-OH 3.13Å; N344-Y398 HydrophobicContact CB-CE1 4.38Å; N344-Y398 WeakPolarHBondContact CB-OH 3.46Å; L345-Y398 HydrophobicContact CD2-CD1 3.77Å; L345-Y398 HydrophobicContact CD2-CD2 3.94Å; L345-Y398 HydrophobicContact CD2-CE1 3.87Å; L345-Y398 HydrophobicContact CD2-CE2 4.03Å; L345-Y398 HydrophobicContact CD2-CG 3.81Å; L345-Y398 HydrophobicContact CG-CE1 4.36Å; L345-Y398 HydrophobicContact CG-CE2 4.49Å; A348-Y398 HydrophobicContact CB-CD1 4.12Å; A348-Y398 HydrophobicContact CB-CE1 4.31Å; L394-Y398 HydrophobicContact CD1-CE2 4.31Å; L394-Y398 HydrophobicContact CD2-CD2 4.29Å; L394-Y398 HydrophobicContact CD2-CE2 3.96Å; L394-Y398 HydrophobicContact CG-CD2 4.04Å; L394-Y398 HydrophobicContact CG-CE2 3.87Å; L394-Y398 WeakPolarHBondContact O-CD2 3.31Å; L394-Y398 PolarHBondContact O-N 3.01Å; I395-Y398 PolarHBondContact O-N 3.07Å; I396-Y398 PolarHBondContact O-N 3.47Å; Y398-V400 VanDerWaalsContact C-N 3.33Å; Y398-V400 PolarHBondContact O-N 2.95Å; Y398-A401 PolarHBondContact O-N 3.22Å; Y398-V402 WeakPolarHBondContact O-CG2 3.36Å; Y398-V402 PolarHBondContact O-N 3.18Å
399	V	91.3	Very high	88.1	Confident	97 Å²	97	54.5 Å²	54.5	59%	0.588	30%	0.299	S	S	*	.	H	α-helix	trans	-61.9	-44	177.2	172.9	0	0	0	0	110.7	I395 I396 V402 A403	I395-V399 WeakPolarHBondContact O-CG2 3.36Å; I395-V399 PolarHBondContact O-N 3.16Å; I395-V399 VanDerWaalsContact O-N 3.08Å; I396-V399 PolarHBondContact O-N 3.34Å; I396-V399 VanDerWaalsContact O-N 3.16Å; V399-V402 PolarHBondContact O-N 2.93Å; V399-A403 WeakPolarHBondContact O-CB 3.44Å; V399-A403 PolarHBondContact O-N 3.46Å
400	V	90.7	Very high	88.5	Confident	6 Å²	6	48.2 Å²	48.2	4%	0.036	27%	0.266	C	S	.	.	H	α-helix	trans	-68.1	-38	177.7	179.7	0	0	0	0	111.9	L386 V387 M390 I396 T397 Y398 A403 A404	L386-V400 HydrophobicContact CD2-CG2 3.3Å; L386-V400 HydrophobicContact CG-CG2 3.74Å; V387-V400 HydrophobicContact CG2-CG1 3.59Å; M390-V400 HydrophobicContact CE-CG2 4.48Å; M390-V400 HydrophobicContact SD-CB 3.96Å; M390-V400 HydrophobicContact SD-CG1 4.14Å; M390-V400 HydrophobicContact SD-CG2 3.58Å; M390-V400 VanDerWaalsContact SD-CG2 3.58Å; I396-V400 HydrophobicContact CG2-CG2 4.31Å; I396-V400 WeakPolarHBondContact O-CG2 3.42Å; I396-V400 PolarHBondContact O-N 2.84Å; T397-V400 PolarHBondContact O-N 3.35Å; Y398-V400 VanDerWaalsContact C-N 3.33Å; Y398-V400 PolarHBondContact O-N 2.95Å; V400-A403 PolarHBondContact O-N 3Å; V400-A404 WeakPolarHBondContact O-CB 3.46Å; V400-A404 PolarHBondContact O-N 3.07Å
401	A	90.2	Very high	89.1	Confident	8 Å²	8	47.6 Å²	47.6	7%	0.066	27%	0.265	C	S	.	.	H	α-helix	trans	-60.4	-47.1	174.5	0	0	0	0	0	111.8	L345 I349 T397 Y398 A403 A404 G405	L345-A401 HydrophobicContact CD2-CB 4.12Å; I349-A401 HydrophobicContact CD1-CB 4.32Å; I349-A401 HydrophobicContact CG1-CB 3.75Å; I349-A401 WeakPolarHBondContact CG1-O 3.14Å; T397-A401 VanDerWaalsContact O-CB 3.25Å; T397-A401 WeakPolarHBondContact O-CB 3.28Å; T397-A401 PolarHBondContact O-N 3.42Å; Y398-A401 PolarHBondContact O-N 3.22Å; A401-A403 VanDerWaalsContact C-N 3.33Å; A401-A403 PolarHBondContact O-N 2.66Å; A401-A404 PolarHBondContact O-N 2.9Å; A401-G405 PolarHBondContact O-N 3.34Å; A401-G405 VanDerWaalsContact O-N 3.15Å
402	V	92.6	Very high	89.8	Confident	73 Å²	73	42.9 Å²	42.9	44%	0.442	24%	0.242	S	C	.	.	H	α-helix	trans	-62.7	-41.2	175.7	170.9	0	0	0	0	111.2	A348 S352 Y398 V399 G405	A348-V402 HydrophobicContact CB-CG2 4.37Å; S352-V402 PolarHBondContact OG-O 3.04Å; Y398-V402 WeakPolarHBondContact O-CG2 3.36Å; Y398-V402 PolarHBondContact O-N 3.18Å; V399-V402 PolarHBondContact O-N 2.93Å; V402-G405 PolarHBondContact O-N 2.97Å
403	A	91.6	Very high	90.7	Very high	22 Å²	22	38.9 Å²	38.9	18%	0.182	22%	0.215	C	C	.	.	H	α-helix	trans	-64.9	-42.1	176.9	0	0	0	0	0	111.7	F383 V399 V400 A401 G405 I406	F383-A403 HydrophobicContact CD1-CB 3.85Å; F383-A403 WeakPolarHBondContact CD2-O 3.39Å; F383-A403 HydrophobicContact CE1-CB 3.54Å; F383-A403 HydrophobicContact CE2-CB 4.26Å; F383-A403 WeakPolarHBondContact CE2-O 3.28Å; F383-A403 HydrophobicContact CG-CB 4.37Å; F383-A403 HydrophobicContact CZ-CB 3.76Å; F383-A403 WeakPolarHBondContact CZ-O 3.17Å; V399-A403 WeakPolarHBondContact O-CB 3.44Å; V399-A403 PolarHBondContact O-N 3.46Å; V400-A403 PolarHBondContact O-N 3Å; A401-A403 VanDerWaalsContact C-N 3.33Å; A401-A403 PolarHBondContact O-N 2.66Å; A403-G405 PolarHBondContact O-N 3.09Å; A403-I406 VanDerWaalsContact O-CB 3.28Å; A403-I406 WeakPolarHBondContact O-CB 3.22Å; A403-I406 PolarHBondContact O-N 3.45Å
404	A	91.4	Very high	91.1	Very high	25 Å²	25	35.6 Å²	35.6	21%	0.207	20%	0.197	C	C	.	.	H	α-helix	trans	-59.2	-35.3	176.6	0	0	0	0	0	112.4	V400 A401 I406 S407 V408	V400-A404 WeakPolarHBondContact O-CB 3.46Å; V400-A404 PolarHBondContact O-N 3.07Å; A401-A404 PolarHBondContact O-N 2.9Å; A404-I406 PolarHBondContact O-N 3.31Å; A404-S407 PolarHBondContact O-N 3.48Å; A404-S407 VanDerWaalsContact O-N 3.07Å; A404-V408 WeakPolarHBondContact O-CG2 2.99Å; A404-V408 PolarHBondContact O-N 2.74Å
405	G	91.9	Very high	91.4	Very high	0 Å²	0	32.4 Å²	32.4	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-55.4	-31.6	174.8	0	0	0	0	0	114	S352 A353 A401 V402 A403 S407 V408 A409	S352-G405 WeakPolarHBondContact OG-CA 3.19Å; A353-G405 WeakPolarHBondContact CA-O 3.42Å; A353-G405 WeakPolarHBondContact CB-O 3.41Å; A401-G405 PolarHBondContact O-N 3.34Å; A401-G405 VanDerWaalsContact O-N 3.15Å; V402-G405 PolarHBondContact O-N 2.97Å; A403-G405 PolarHBondContact O-N 3.09Å; G405-S407 PolarHBondContact O-N 2.9Å; G405-V408 PolarHBondContact O-N 3.5Å; G405-A409 WeakPolarHBondContact O-CB 3.3Å; G405-A409 PolarHBondContact O-N 3.41Å
406	I	92.8	Very high	91.7	Very high	65 Å²	65	27.5 Å²	27.5	33%	0.333	15%	0.154	S	C	.	.	H	α-helix	trans	-61.1	-46.8	176	-61.9	171	0	0	0	110.7	T356 W360 A403 A404 A410	T356-I406 HydrophobicContact CG2-CB 4.23Å; T356-I406 HydrophobicContact CG2-CG1 4.14Å; T356-I406 HydrophobicContact CG2-CG2 4.03Å; W360-I406 HydrophobicContact CZ2-CG2 3.99Å; W360-I406 PolarHBondContact NE1-O 3.03Å; A403-I406 VanDerWaalsContact O-CB 3.28Å; A403-I406 WeakPolarHBondContact O-CB 3.22Å; A403-I406 PolarHBondContact O-N 3.45Å; A404-I406 PolarHBondContact O-N 3.31Å; I406-A410 PolarHBondContact O-N 3.47Å
407	S	92.8	Very high	91.9	Very high	1 Å²	1	23.8 Å²	23.8	1%	0.007	14%	0.135	C	C	.	.	H	α-helix	trans	-74.3	-36.4	-179.1	-56.5	0	0	0	0	112.1	S379 A380 F383 A404 G405 A409 A410 A411	S379-S407 WeakPolarHBondContact CB-OG 3.41Å; S379-S407 PolarHBondContact O-OG 3.49Å; S379-S407 PolarHBondContact OG-OG 3.48Å; A380-S407 WeakPolarHBondContact CA-OG 3.29Å; A380-S407 PolarHBondContact N-OG 3.27Å; F383-S407 WeakPolarHBondContact CD2-OG 3.47Å; F383-S407 VanDerWaalsContact CE2-OG 3.24Å; F383-S407 WeakPolarHBondContact CE2-OG 3.5Å; A404-S407 PolarHBondContact O-N 3.48Å; A404-S407 VanDerWaalsContact O-N 3.07Å; G405-S407 PolarHBondContact O-N 2.9Å; S407-A409 VanDerWaalsContact C-N 3.34Å; S407-A409 PolarHBondContact O-N 2.91Å; S407-A410 WeakPolarHBondContact O-CB 3.44Å; S407-A410 PolarHBondContact O-N 2.92Å; S407-A411 PolarHBondContact O-N 2.81Å
408	V	92.5	Very high	92.1	Very high	19 Å²	19	23.4 Å²	23.4	12%	0.115	13%	0.132	C	C	.	.	H	α-helix	trans	-60.3	-44.5	175.1	172.1	0	0	0	0	110.6	F321 I349 A353 A404 G405 A410 A411 F412	F321-V408 HydrophobicContact CD1-CG2 4.16Å; F321-V408 HydrophobicContact CE1-CG2 3.92Å; I349-V408 HydrophobicContact CG2-CG2 4.28Å; A353-V408 HydrophobicContact CB-CG1 4.32Å; A404-V408 WeakPolarHBondContact O-CG2 2.99Å; A404-V408 PolarHBondContact O-N 2.74Å; G405-V408 PolarHBondContact O-N 3.5Å; V408-A410 VanDerWaalsContact C-N 3.32Å; V408-A410 PolarHBondContact O-N 3.05Å; V408-A411 PolarHBondContact O-N 3.48Å; V408-F412 HydrophobicContact CG1-CD2 3.57Å; V408-F412 HydrophobicContact CG1-CE2 3.5Å; V408-F412 VanDerWaalsContact O-CD2 3.3Å; V408-F412 WeakPolarHBondContact O-CD2 3.43Å; V408-F412 PolarHBondContact O-N 3.46Å
409	A	93.9	Very high	92.3	Very high	1 Å²	1	20.6 Å²	20.6	1%	0.008	12%	0.121	C	C	.	.	H	α-helix	trans	-58.4	-41.6	176.1	0	0	0	0	0	112.9	A353 I357 G405 S407 L413	A353-A409 HydrophobicContact CB-CB 4.16Å; A353-A409 WeakPolarHBondContact O-CB 3.49Å; I357-A409 HydrophobicContact CG1-CB 3.95Å; G405-A409 WeakPolarHBondContact O-CB 3.3Å; G405-A409 PolarHBondContact O-N 3.41Å; S407-A409 VanDerWaalsContact C-N 3.34Å; S407-A409 PolarHBondContact O-N 2.91Å; A409-L413 VanDerWaalsContact O-CB 3.29Å; A409-L413 WeakPolarHBondContact O-CB 3.24Å; A409-L413 PolarHBondContact O-N 3.34Å
410	A	93.4	Very high	92.3	Very high	0 Å²	0	16 Å²	16	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-63.1	-48.2	175.6	0	0	0	0	0	111	W360 I406 S407 V408 F412 L413 L414	W360-A410 HydrophobicContact CD2-CB 3.99Å; W360-A410 HydrophobicContact CG-CB 4.37Å; W360-A410 HydrophobicContact CZ2-CB 3.95Å; I406-A410 PolarHBondContact O-N 3.47Å; S407-A410 WeakPolarHBondContact O-CB 3.44Å; S407-A410 PolarHBondContact O-N 2.92Å; V408-A410 VanDerWaalsContact C-N 3.32Å; V408-A410 PolarHBondContact O-N 3.05Å; A410-F412 VanDerWaalsContact C-N 3.28Å; A410-F412 PolarHBondContact O-N 3.43Å; A410-L413 PolarHBondContact O-N 3.3Å; A410-L414 HydrophobicContact CB-CD1 3.92Å; A410-L414 WeakPolarHBondContact O-CB 3.28Å; A410-L414 VanDerWaalsContact O-CD1 3.25Å; A410-L414 WeakPolarHBondContact O-CD1 3.47Å; A410-L414 WeakPolarHBondContact O-CG 3.46Å; A410-L414 PolarHBondContact O-N 2.99Å
411	A	91.8	Very high	92.4	Very high	17 Å²	17	15.9 Å²	15.9	14%	0.14	9%	0.093	C	C	.	.	H	α-helix	trans	-59.9	-37.1	-178.5	0	0	0	0	0	112.9	F321 S407 V408 P415	F321-A411 HydrophobicContact CD2-CB 3.67Å; F321-A411 HydrophobicContact CE1-CB 4.18Å; F321-A411 HydrophobicContact CE2-CB 3.3Å; F321-A411 HydrophobicContact CG-CB 4.3Å; F321-A411 HydrophobicContact CZ-CB 3.58Å; S407-A411 PolarHBondContact O-N 2.81Å; V408-A411 PolarHBondContact O-N 3.48Å; A411-P415 WeakPolarHBondContact O-CD 3.16Å; A411-P415 VanDerWaalsContact O-CG 3.29Å; A411-P415 WeakPolarHBondContact O-CG 3.25Å
412	F	90.1	Very high	92.6	Very high	70 Å²	70	15.5 Å²	15.5	31%	0.307	9%	0.09	S	C	.	.	H	α-helix	trans	-75.6	-37.8	175	-80.2	-68.1	0	0	0	113.2	M200 V408 A410	M200-F412 HydrophobicContact SD-CB 4.41Å; V408-F412 HydrophobicContact CG1-CD2 3.57Å; V408-F412 HydrophobicContact CG1-CE2 3.5Å; V408-F412 VanDerWaalsContact O-CD2 3.3Å; V408-F412 WeakPolarHBondContact O-CD2 3.43Å; V408-F412 PolarHBondContact O-N 3.46Å; A410-F412 VanDerWaalsContact C-N 3.28Å; A410-F412 PolarHBondContact O-N 3.43Å
413	L	93.1	Very high	92.6	Very high	0 Å²	0	12 Å²	12	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-78.5	-44.2	-173.9	-178.2	65.3	0	0	0	113.8	T196 A197 M200 I357 W360 Q361 L364 A409 A410 W416 S417	T196-L413 HydrophobicContact CG2-CD1 4.21Å; A197-L413 HydrophobicContact CB-CD1 4.03Å; M200-L413 HydrophobicContact CB-CD1 4.28Å; M200-L413 HydrophobicContact CG-CD1 3.84Å; I357-L413 HydrophobicContact CG2-CD1 4.39Å; I357-L413 HydrophobicContact CG2-CD2 4.39Å; W360-L413 HydrophobicContact CB-CD2 3.71Å; Q361-L413 HydrophobicContact CB-CD2 4.5Å; L364-L413 HydrophobicContact CD1-CD2 3.56Å; L364-L413 HydrophobicContact CD1-CG 4.02Å; A409-L413 VanDerWaalsContact O-CB 3.29Å; A409-L413 WeakPolarHBondContact O-CB 3.24Å; A409-L413 PolarHBondContact O-N 3.34Å; A410-L413 PolarHBondContact O-N 3.3Å; L413-W416 PolarHBondContact O-N 3.34Å; L413-S417 PolarHBondContact O-N 3.44Å
414	L	92.8	Very high	92.6	Very high	1 Å²	1	11.2 Å²	11.2	1%	0.005	6%	0.062	C	C	.	.	H	α-helix	trans	-62.1	-44	-167.3	-69	164.4	0	0	0	115.2	F314 L364 A372 V373 I377 A410 W416 S417 M418	F314-L414 HydrophobicContact CE1-CB 4.3Å; F314-L414 HydrophobicContact CZ-CB 4.36Å; L364-L414 HydrophobicContact CD1-CD2 4.28Å; L364-L414 HydrophobicContact CD2-CD2 3.49Å; L364-L414 VanDerWaalsContact CD2-CD2 3.49Å; L364-L414 HydrophobicContact CG-CD2 4.27Å; A372-L414 HydrophobicContact CB-CD2 3.84Å; V373-L414 HydrophobicContact CB-CD1 4.26Å; V373-L414 HydrophobicContact CG2-CB 4.16Å; V373-L414 HydrophobicContact CG2-CD1 3.9Å; V373-L414 HydrophobicContact CG2-CD2 3.91Å; V373-L414 HydrophobicContact CG2-CG 4.23Å; I377-L414 HydrophobicContact CD1-CD1 4.47Å; I377-L414 HydrophobicContact CG1-CD1 4.2Å; A410-L414 HydrophobicContact CB-CD1 3.92Å; A410-L414 WeakPolarHBondContact O-CB 3.28Å; A410-L414 VanDerWaalsContact O-CD1 3.25Å; A410-L414 WeakPolarHBondContact O-CD1 3.47Å; A410-L414 WeakPolarHBondContact O-CG 3.46Å; A410-L414 PolarHBondContact O-N 2.99Å; L414-W416 VanDerWaalsContact C-N 3.28Å; L414-W416 PolarHBondContact O-N 3.39Å; L414-S417 PolarHBondContact O-N 2.65Å; L414-M418 WeakPolarHBondContact O-CG 3.42Å; L414-M418 PolarHBondContact O-N 3.02Å
415	P	92.7	Very high	92.7	Very high	2 Å²	2	10.1 Å²	10.1	1%	0.013	5%	0.052	C	C	.	.	H	α-helix	trans	-58.4	-42.9	-178	-17.2	25.2	0	0	0	112.6	F314 A411 S417 M418 L419 Y444	F314-P415 HydrophobicContact CD1-CB 3.95Å; F314-P415 HydrophobicContact CD1-CG 3.55Å; F314-P415 HydrophobicContact CD2-CB 3.93Å; F314-P415 HydrophobicContact CD2-CG 4.44Å; F314-P415 HydrophobicContact CE1-CB 3.94Å; F314-P415 HydrophobicContact CE1-CG 3.54Å; F314-P415 VanDerWaalsContact CE2-CA 3.49Å; F314-P415 HydrophobicContact CE2-CB 3.88Å; F314-P415 HydrophobicContact CE2-CG 4.41Å; F314-P415 HydrophobicContact CG-CB 3.98Å; F314-P415 HydrophobicContact CG-CG 4.06Å; F314-P415 HydrophobicContact CZ-CB 3.91Å; F314-P415 HydrophobicContact CZ-CG 4.01Å; A411-P415 WeakPolarHBondContact O-CD 3.16Å; A411-P415 VanDerWaalsContact O-CG 3.29Å; A411-P415 WeakPolarHBondContact O-CG 3.25Å; P415-S417 VanDerWaalsContact C-N 3.34Å; P415-S417 PolarHBondContact O-N 2.91Å; P415-M418 PolarHBondContact O-N 3.4Å; P415-L419 VanDerWaalsContact O-CB 3.27Å; P415-L419 WeakPolarHBondContact O-CB 3.21Å; P415-L419 PolarHBondContact O-N 3.38Å; P415-Y444 HydrophobicContact CB-CE1 4.38Å; P415-Y444 HydrophobicContact CB-CE2 3.74Å; P415-Y444 VanDerWaalsContact CB-CZ 3.46Å; P415-Y444 WeakPolarHBondContact CB-OH 3.47Å; P415-Y444 VanDerWaalsContact CG-OH 3.31Å; P415-Y444 WeakPolarHBondContact CG-OH 3.36Å
416	W	92	Very high	92.7	Very high	21 Å²	21	10.2 Å²	10.2	8%	0.08	5%	0.053	C	C	.	.	H	α-helix	trans	-76.4	-22.2	-176.6	-59.9	101.1	0	0	0	113.6	T196 M200 L413 L414 P420 F441 Y444 V445	T196-W416 HydrophobicContact CG2-CB 3.54Å; M200-W416 HydrophobicContact CE-CB 3.77Å; M200-W416 HydrophobicContact CE-CD2 4.02Å; M200-W416 HydrophobicContact CE-CG 3.35Å; L413-W416 PolarHBondContact O-N 3.34Å; L414-W416 VanDerWaalsContact C-N 3.28Å; L414-W416 PolarHBondContact O-N 3.39Å; W416-P420 WeakPolarHBondContact O-CD 3.08Å; W416-F441 HydrophobicContact CE3-CD1 4Å; W416-F441 AromaticContact CE3-CE1 3.95Å; W416-F441 HydrophobicContact CE3-CE1 3.95Å; W416-F441 AromaticContact CZ3-CD1 3.72Å; W416-F441 HydrophobicContact CZ3-CD1 3.72Å; W416-F441 HydrophobicContact CZ3-CE1 4.12Å; W416-Y444 HydrophobicContact CD2-CE1 4.05Å; W416-Y444 AromaticContact CE2-CE1 3.66Å; W416-Y444 HydrophobicContact CE3-CD1 4.44Å; W416-Y444 HydrophobicContact CE3-CE1 4.32Å; W416-Y444 HydrophobicContact CH2-CD1 4.05Å; W416-Y444 AromaticContact CH2-CE1 3.98Å; W416-Y444 HydrophobicContact CH2-CE1 3.98Å; W416-Y444 HydrophobicContact CZ2-CD1 4.2Å; W416-Y444 AromaticContact CZ2-CE1 3.65Å; W416-Y444 HydrophobicContact CZ2-CE1 3.65Å; W416-Y444 HydrophobicContact CZ3-CD1 4.16Å; W416-Y444 HydrophobicContact CZ3-CE1 4.28Å; W416-V445 HydrophobicContact CH2-CG2 3.66Å; W416-V445 HydrophobicContact CZ2-CG2 4.46Å; W416-V445 HydrophobicContact CZ3-CG2 4.43Å
417	S	92.8	Very high	92.4	Very high	0 Å²	0	7.8 Å²	7.8	0%	0	4%	0.04	C	C	.	.	H	α-helix	trans	-80.9	-33.4	171.2	177.1	0	0	0	0	111.9	D193 K369 L413 L414 P415	D193-S417 VanDerWaalsContact CG-OG 3.3Å; D193-S417 PolarHBondContact OD1-OG 3.04Å; K369-S417 VanDerWaalsContact CD-OG 3.29Å; K369-S417 WeakPolarHBondContact CD-OG 3.42Å; K369-S417 VanDerWaalsContact CE-OG 3.25Å; K369-S417 WeakPolarHBondContact CE-OG 3.21Å; K369-S417 PolarHBondContact NZ-O 3.16Å; K369-S417 PolarHBondContact NZ-OG 2.91Å; L413-S417 PolarHBondContact O-N 3.44Å; L414-S417 PolarHBondContact O-N 2.65Å; P415-S417 VanDerWaalsContact C-N 3.34Å; P415-S417 PolarHBondContact O-N 2.91Å
418	M	93.9	Very high	92.3	Very high	2 Å²	2	10 Å²	10	1%	0.01	5%	0.051	C	C	.	.	H	α-helix	trans	-85.5	-27	-178.5	-69.3	-175.9	75.5	0	0	114.2	L310 F314 K369 V373 L414 P415 D421 V422 Y505	L310-M418 HydrophobicContact CD1-CB 4.22Å; L310-M418 HydrophobicContact CD1-CE 3.65Å; L310-M418 HydrophobicContact CD1-SD 4.17Å; L310-M418 HydrophobicContact CD2-CB 4.12Å; F314-M418 HydrophobicContact CE2-CB 4.47Å; F314-M418 HydrophobicContact CE2-SD 4.42Å; F314-M418 HydrophobicContact CZ-SD 3.96Å; K369-M418 HydrophobicContact CB-CG 4.01Å; K369-M418 HydrophobicContact CB-SD 4.47Å; K369-M418 HydrophobicContact CD-CG 4.07Å; V373-M418 HydrophobicContact CG2-CE 4.35Å; V373-M418 HydrophobicContact CG2-SD 3.3Å; V373-M418 WeakPolarHBondContact CG2-SD 3.47Å; L414-M418 WeakPolarHBondContact O-CG 3.42Å; L414-M418 PolarHBondContact O-N 3.02Å; P415-M418 PolarHBondContact O-N 3.4Å; M418-D421 WeakPolarHBondContact O-CB 3.45Å; M418-D421 PolarHBondContact O-N 3.02Å; M418-D421 VanDerWaalsContact O-N 3.09Å; M418-V422 PolarHBondContact O-N 2.97Å; M418-Y505 HydrophobicContact CE-CD1 3.87Å; M418-Y505 HydrophobicContact CE-CE1 3.39Å
419	L	93.5	Very high	92	Very high	2 Å²	2	13.5 Å²	13.5	1%	0.01	7%	0.065	C	C	.	.	H	α-helix	trans	-58.5	-45.2	179.8	-178.5	62.9	0	0	0	112.9	Y307 P415 D421 V422 I423 F440 F441 Y444	Y307-L419 HydrophobicContact CD2-CD1 4.18Å; Y307-L419 HydrophobicContact CE2-CD1 3.66Å; P415-L419 VanDerWaalsContact O-CB 3.27Å; P415-L419 WeakPolarHBondContact O-CB 3.21Å; P415-L419 PolarHBondContact O-N 3.38Å; L419-D421 VanDerWaalsContact C-N 3.26Å; L419-D421 PolarHBondContact O-N 3.37Å; L419-V422 PolarHBondContact O-N 3.11Å; L419-V422 VanDerWaalsContact O-N 3.16Å; L419-I423 HydrophobicContact CG-CD1 4.33Å; L419-I423 WeakPolarHBondContact O-CG1 3.36Å; L419-I423 PolarHBondContact O-N 3.45Å; L419-F440 HydrophobicContact CD1-CB 4.44Å; L419-F441 HydrophobicContact CD2-CD1 3.38Å; L419-F441 HydrophobicContact CD2-CE1 3.56Å; L419-F441 HydrophobicContact CD2-CG 3.98Å; L419-F441 HydrophobicContact CD2-CZ 4.23Å; L419-F441 HydrophobicContact CG-CD1 4.43Å; L419-F441 HydrophobicContact CG-CE1 4.26Å; L419-Y444 HydrophobicContact CD2-CD1 4.36Å; L419-Y444 HydrophobicContact CD2-CG 4.19Å
420	P	92.5	Very high	91.6	Very high	2 Å²	2	16.8 Å²	16.8	1%	0.013	8%	0.08	C	C	.	.	H	α-helix	trans	-51.9	-38.1	170	-32.6	38.8	0	0	0	115.1	M183 W416 V422 I423 D424	M183-P420 HydrophobicContact SD-CB 3.56Å; M183-P420 VanDerWaalsContact SD-CB 3.56Å; M183-P420 HydrophobicContact SD-CG 4Å; W416-P420 WeakPolarHBondContact O-CD 3.08Å; P420-V422 VanDerWaalsContact C-N 3.27Å; P420-V422 PolarHBondContact O-N 2.9Å; P420-I423 PolarHBondContact O-N 2.83Å; P420-D424 PolarHBondContact O-N 3.3Å
421	D	93	Very high	90.8	Very high	2 Å²	2	19.6 Å²	19.6	1%	0.011	10%	0.098	C	C	.	.	H	α-helix	trans	-66.1	-33	-177.5	-57.2	-26.5	0	0	0	111.7	K369 M418 L419 D425 R512	K369-D421 VanDerWaalsContact CD-OD2 3.31Å; K369-D421 WeakPolarHBondContact CD-OD2 3.26Å; K369-D421 VanDerWaalsContact NZ-CG 3.34Å; K369-D421 IonicContact NZ-OD1 2.68Å; K369-D421 PolarHBondContact NZ-OD1 2.91Å; K369-D421 IonicContact NZ-OD2 3.64Å; K369-D421 PolarHBondContact NZ-OD2 3.27Å; K369-D421 VanDerWaalsContact NZ-OD2 3.13Å; M418-D421 WeakPolarHBondContact O-CB 3.45Å; M418-D421 PolarHBondContact O-N 3.02Å; M418-D421 VanDerWaalsContact O-N 3.09Å; L419-D421 VanDerWaalsContact C-N 3.26Å; L419-D421 PolarHBondContact O-N 3.37Å; D421-D425 PolarHBondContact O-N 3.48Å; D421-D425 VanDerWaalsContact O-N 3.11Å; D421-R512 HydrophobicContact CB-CG 4.46Å; D421-R512 VanDerWaalsContact OD2-CD 3.32Å; D421-R512 WeakPolarHBondContact OD2-CD 3.44Å; D421-R512 IonicContact OD2-CZ 3.47Å; D421-R512 IonicContact OD2-NE 3.82Å; D421-R512 IonicContact OD2-NH1 3.53Å; D421-R512 PolarHBondContact OD2-NH1 3.07Å
422	V	94.3	Very high	89.9	Confident	0 Å²	0	24.8 Å²	24.8	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-74	-38.1	176.2	179.1	0	0	0	0	111.1	Y307 L310 M418 L419 P420 D425 F426 F440 Y505 I507	Y307-V422 HydrophobicContact CD2-CG1 4.03Å; Y307-V422 HydrophobicContact CG-CG1 4.29Å; L310-V422 HydrophobicContact CD2-CG2 3.5Å; L310-V422 VanDerWaalsContact CD2-CG2 3.5Å; M418-V422 PolarHBondContact O-N 2.97Å; L419-V422 PolarHBondContact O-N 3.11Å; L419-V422 VanDerWaalsContact O-N 3.16Å; P420-V422 VanDerWaalsContact C-N 3.27Å; P420-V422 PolarHBondContact O-N 2.9Å; V422-D425 PolarHBondContact O-N 2.69Å; V422-F426 WeakPolarHBondContact O-CB 3.45Å; V422-F426 PolarHBondContact O-N 2.73Å; V422-F440 HydrophobicContact CG1-CE1 4.35Å; V422-Y505 HydrophobicContact CG2-CE2 3.92Å; V422-Y505 WeakPolarHBondContact CG2-OH 3.27Å; V422-I507 HydrophobicContact CG2-CD1 4.08Å
423	I	91.9	Very high	89.1	Confident	0 Å²	0	23.4 Å²	23.4	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-64.2	-45.2	176.6	-61.8	168.5	0	0	0	109.4	M183 L419 P420 D425 F426 H427 E437 F440 F441	M183-I423 HydrophobicContact CE-CB 4.07Å; M183-I423 HydrophobicContact CE-CG2 3.75Å; M183-I423 HydrophobicContact CG-CD1 4.33Å; M183-I423 HydrophobicContact SD-CD1 4.49Å; L419-I423 HydrophobicContact CG-CD1 4.33Å; L419-I423 WeakPolarHBondContact O-CG1 3.36Å; L419-I423 PolarHBondContact O-N 3.45Å; P420-I423 PolarHBondContact O-N 2.83Å; I423-D425 VanDerWaalsContact C-N 3.35Å; I423-D425 PolarHBondContact O-N 3.41Å; I423-F426 WeakPolarHBondContact O-CB 3.21Å; I423-F426 PolarHBondContact O-N 2.93Å; I423-F426 VanDerWaalsContact O-N 3.14Å; I423-H427 PolarHBondContact O-CD2 2.87Å; I423-H427 PolarHBondContact O-N 2.98Å; I423-E437 HydrophobicContact CG2-CB 4.34Å; I423-E437 HydrophobicContact CG2-CG 3.88Å; I423-F440 HydrophobicContact CD1-CB 3.82Å; I423-F440 HydrophobicContact CD1-CG 4.27Å; I423-F440 HydrophobicContact CG1-CB 3.85Å; I423-F440 HydrophobicContact CG1-CD1 4.08Å; I423-F440 HydrophobicContact CG1-CD2 4.02Å; I423-F440 HydrophobicContact CG1-CG 3.74Å; I423-F441 HydrophobicContact CD1-CD2 4.09Å; I423-F441 HydrophobicContact CD1-CE2 3.58Å; I423-F441 HydrophobicContact CD1-CZ 4.24Å
424	D	91.4	Very high	88.1	Confident	6 Å²	6	24.5 Å²	24.5	3%	0.032	12%	0.119	C	C	.	.	H	α-helix	trans	-58.6	-43.1	174.1	-76	-8.3	0	0	0	111.6	Q189 R192 P420 F426 L428 L519	Q189-D424 PolarHBondContact NE2-OD2 2.7Å; R192-D424 IonicContact NH1-OD1 2.87Å; R192-D424 PolarHBondContact NH1-OD1 2.91Å; R192-D424 VanDerWaalsContact NH1-OD1 3.08Å; R192-D424 IonicContact NH1-OD2 3.91Å; P420-D424 PolarHBondContact O-N 3.3Å; D424-F426 VanDerWaalsContact C-N 3.35Å; D424-L428 WeakPolarHBondContact O-CG 3.22Å; D424-L428 PolarHBondContact O-N 2.76Å; D424-L519 HydrophobicContact CB-CD1 3.73Å
425	D	93.3	Very high	87.2	Confident	2 Å²	2	24.7 Å²	24.7	1%	0.011	12%	0.121	C	C	.	.	H	α-helix	trans	-66.6	-34.8	175.5	-170.6	74	0	0	0	112.6	H304 D421 V422 I423 K429 I507 R511 N515	H304-D425 IonicContact CE1-OD2 2.89Å; H304-D425 IonicContact NE2-OD2 3.97Å; H304-D425 PolarHBondContact NE2-OD2 3.08Å; D421-D425 PolarHBondContact O-N 3.48Å; D421-D425 VanDerWaalsContact O-N 3.11Å; V422-D425 PolarHBondContact O-N 2.69Å; I423-D425 VanDerWaalsContact C-N 3.35Å; I423-D425 PolarHBondContact O-N 3.41Å; D425-K429 PolarHBondContact O-N 3.36Å; D425-K429 IonicContact OD1-NZ 3.69Å; D425-K429 WeakPolarHBondContact OD2-CE 3.23Å; D425-K429 IonicContact OD2-NZ 2.63Å; D425-K429 PolarHBondContact OD2-NZ 3.14Å; D425-I507 HydrophobicContact CB-CD1 3.75Å; D425-R511 IonicContact OD1-NE 2.66Å; D425-R511 IonicContact OD1-NH2 3.12Å; D425-N515 WeakPolarHBondContact CA-ND2 3.26Å; D425-N515 VanDerWaalsContact CB-ND2 3.31Å; D425-N515 WeakPolarHBondContact CB-ND2 3.29Å; D425-N515 PolarHBondContact OD1-ND2 3.01Å
426	F	91.7	Very high	86.7	Confident	2 Å²	2	24.7 Å²	24.7	1%	0.009	12%	0.12	C	C	.	.	H	α-helix	trans	-67.3	-45.7	176.9	178	-99.4	0	0	0	111.3	L300 H304 V422 I423 D424 L428 K429 Q430 T436 F440	L300-F426 HydrophobicContact CD2-CE2 4.43Å; L300-F426 HydrophobicContact CD2-CZ 3.74Å; L300-F426 HydrophobicContact CG-CE2 4.02Å; L300-F426 HydrophobicContact CG-CZ 3.8Å; H304-F426 HydrophobicContact CB-CD2 4.09Å; H304-F426 AromaticContact CD2-CD2 3.96Å; H304-F426 AromaticContact CG-CD2 3.88Å; V422-F426 WeakPolarHBondContact O-CB 3.45Å; V422-F426 PolarHBondContact O-N 2.73Å; I423-F426 WeakPolarHBondContact O-CB 3.21Å; I423-F426 PolarHBondContact O-N 2.93Å; I423-F426 VanDerWaalsContact O-N 3.14Å; D424-F426 VanDerWaalsContact C-N 3.35Å; F426-L428 VanDerWaalsContact C-N 3.26Å; F426-L428 PolarHBondContact O-N 3.29Å; F426-K429 PolarHBondContact O-N 2.82Å; F426-K429 VanDerWaalsContact O-N 3.07Å; F426-Q430 HydrophobicContact CD2-CG 4.43Å; F426-Q430 HydrophobicContact CE1-CB 4.34Å; F426-Q430 HydrophobicContact CE2-CB 4.22Å; F426-Q430 HydrophobicContact CE2-CG 3.95Å; F426-Q430 HydrophobicContact CZ-CB 4.05Å; F426-Q430 HydrophobicContact CZ-CG 4.2Å; F426-Q430 PolarHBondContact O-N 3.09Å; F426-T436 HydrophobicContact CE1-CG2 4.28Å; F426-T436 WeakPolarHBondContact CE1-OG1 3.22Å; F426-F440 HydrophobicContact CB-CE2 4.47Å; F426-F440 HydrophobicContact CB-CZ 3.92Å; F426-F440 AromaticContact CD1-CE2 3.65Å; F426-F440 HydrophobicContact CD1-CE2 3.65Å; F426-F440 AromaticContact CD1-CZ 3.75Å; F426-F440 HydrophobicContact CD1-CZ 3.75Å; F426-F440 AromaticContact CD2-CZ 3.86Å; F426-F440 HydrophobicContact CD2-CZ 3.86Å; F426-F440 AromaticContact CE1-CE2 4Å; F426-F440 HydrophobicContact CE1-CE2 4Å; F426-F440 HydrophobicContact CE1-CZ 4.25Å; F426-F440 HydrophobicContact CE2-CZ 4.31Å; F426-F440 AromaticContact CG-CE2 3.98Å; F426-F440 HydrophobicContact CG-CE2 3.98Å; F426-F440 AromaticContact CG-CZ 3.56Å; F426-F440 HydrophobicContact CG-CZ 3.56Å; F426-F440 HydrophobicContact CZ-CZ 4.49Å
427	H	87.7	Confident	86.5	Confident	13 Å²	13	23.8 Å²	23.8	6%	0.06	12%	0.117	C	C	.	.	H	α-helix	trans	-58	-38.3	177.5	-70.9	-172.9	0	0	0	112.2	I423 K429 Q430 P431 E437	I423-H427 PolarHBondContact O-CD2 2.87Å; I423-H427 PolarHBondContact O-N 2.98Å; H427-K429 VanDerWaalsContact C-N 3.35Å; H427-K429 PolarHBondContact O-N 3.36Å; H427-Q430 CarbonylContact O-C 3.51Å; H427-P431 WeakPolarHBondContact O-CA 3.43Å; H427-E437 IonicContact CE1-OE1 2.69Å; H427-E437 PolarHBondContact CE1-OE1 3.07Å; H427-E437 IonicContact NE2-OE1 2.91Å; H427-E437 PolarHBondContact NE2-OE1 3.49Å
428	L	88.9	Confident	86.2	Confident	47 Å²	47	23.8 Å²	23.8	25%	0.246	12%	0.117	C	C	.	.	H	α-helix	trans	-69.7	-30.2	177.9	-70.5	173.2	0	0	0	113.6	D424 F426 N515 A518 L519 L522	D424-L428 WeakPolarHBondContact O-CG 3.22Å; D424-L428 PolarHBondContact O-N 2.76Å; F426-L428 VanDerWaalsContact C-N 3.26Å; F426-L428 PolarHBondContact O-N 3.29Å; L428-N515 HydrophobicContact CD1-CB 3.55Å; L428-A518 HydrophobicContact CD1-CB 4.01Å; L428-A518 HydrophobicContact CD2-CB 3.75Å; L428-L519 HydrophobicContact CD1-CG 4.28Å; L428-L519 HydrophobicContact CD2-CD2 3.77Å; L428-L519 HydrophobicContact CD2-CG 3.93Å; L428-L519 HydrophobicContact CG-CD2 4.05Å; L428-L519 HydrophobicContact CG-CG 4.11Å; L428-L522 HydrophobicContact CD2-CD1 3.92Å
429	K	88	Confident	85.9	Confident	94 Å²	94	24 Å²	24	41%	0.409	12%	0.119	S	C	.	.	H	α-helix	trans	-87.9	-27.9	180	-74	173.1	177.6	161.4	0	113.1	H304 D425 F426 H427 P431	H304-K429 PolarHBondContact NE2-NZ 2.78Å; D425-K429 PolarHBondContact O-N 3.36Å; D425-K429 IonicContact OD1-NZ 3.69Å; D425-K429 WeakPolarHBondContact OD2-CE 3.23Å; D425-K429 IonicContact OD2-NZ 2.63Å; D425-K429 PolarHBondContact OD2-NZ 3.14Å; F426-K429 PolarHBondContact O-N 2.82Å; F426-K429 VanDerWaalsContact O-N 3.07Å; H427-K429 VanDerWaalsContact C-N 3.35Å; H427-K429 PolarHBondContact O-N 3.36Å; K429-P431 VanDerWaalsContact C-CD 3.48Å
430	Q	84.9	Confident	85.8	Confident	69 Å²	69	24 Å²	24	32%	0.322	12%	0.118	S	C	.	.			trans	-129.3	66.4	-175	-68.3	-70.1	-35.1	0	0	109.5	F426 H427 H432 F433	F426-Q430 HydrophobicContact CD2-CG 4.43Å; F426-Q430 HydrophobicContact CE1-CB 4.34Å; F426-Q430 HydrophobicContact CE2-CB 4.22Å; F426-Q430 HydrophobicContact CE2-CG 3.95Å; F426-Q430 HydrophobicContact CZ-CB 4.05Å; F426-Q430 HydrophobicContact CZ-CG 4.2Å; F426-Q430 PolarHBondContact O-N 3.09Å; H427-Q430 CarbonylContact O-C 3.51Å; Q430-H432 PolarHBondContact O-N 2.87Å; Q430-F433 HydrophobicContact CB-CD2 4.28Å; Q430-F433 PolarHBondContact O-N 3.05Å
431	P	76.2	Confident	85.8	Confident	60 Å²	60	24 Å²	24	39%	0.39	12%	0.118	S	C	.	.	T	Hydrogen-bonded Turn	trans	-65.4	-21.3	-174.3	26.7	-35.2	0	0	0	113.4	H427 K429 F433 H434	H427-P431 WeakPolarHBondContact O-CA 3.43Å; K429-P431 VanDerWaalsContact C-CD 3.48Å; P431-F433 VanDerWaalsContact C-N 3.3Å; P431-F433 PolarHBondContact O-N 3.23Å; P431-H434 PolarHBondContact O-CE1 2.96Å; P431-H434 PolarHBondContact O-NE2 3.34Å
432	H	72.6	Confident	85.6	Confident	125 Å²	125	23.9 Å²	23.9	58%	0.579	12%	0.118	S	C	*	.	T	Hydrogen-bonded Turn	trans	-76.4	-14.9	-179.8	-59.3	-58.3	0	0	0	114.1	Q430	Q430-H432 PolarHBondContact O-N 2.87Å
433	F	73.1	Confident	85.4	Confident	41 Å²	41	25.1 Å²	25.1	18%	0.18	12%	0.123	C	C	.	.			trans	-112.3	97.2	-173.7	-66.4	-65	0	0	0	110.9	I292 L300 Q430 P431	I292-F433 HydrophobicContact CD1-CB 3.86Å; I292-F433 HydrophobicContact CD1-CD1 3.36Å; I292-F433 HydrophobicContact CD1-CE1 4.24Å; I292-F433 HydrophobicContact CD1-CG 3.99Å; I292-F433 HydrophobicContact CG1-CD1 3.67Å; I292-F433 HydrophobicContact CG1-CE1 4.17Å; L300-F433 HydrophobicContact CD2-CB 4.08Å; L300-F433 HydrophobicContact CD2-CD1 4.25Å; L300-F433 HydrophobicContact CD2-CD2 3.48Å; L300-F433 VanDerWaalsContact CD2-CD2 3.48Å; L300-F433 HydrophobicContact CD2-CE2 3.87Å; L300-F433 HydrophobicContact CD2-CG 3.67Å; L300-F433 HydrophobicContact CD2-CZ 4.39Å; Q430-F433 HydrophobicContact CB-CD2 4.28Å; Q430-F433 PolarHBondContact O-N 3.05Å; P431-F433 VanDerWaalsContact C-N 3.3Å; P431-F433 PolarHBondContact O-N 3.23Å
434	H	71.9	Confident	85.4	Confident	24 Å²	24	25.7 Å²	25.7	11%	0.111	13%	0.125	C	C	.	.			trans	-101	160.9	177.1	-66.1	-61.8	0	0	0	112.6	Y284 P431 T436	Y284-H434 AromaticContact CD2-CE1 3.56Å; Y284-H434 AromaticContact CE2-CE1 3.41Å; Y284-H434 VanDerWaalsContact CE2-CE1 3.41Å; Y284-H434 WeakPolarHBondContact CE2-CE1 3.46Å; Y284-H434 AromaticContact CE2-ND1 3.88Å; P431-H434 PolarHBondContact O-CE1 2.96Å; P431-H434 PolarHBondContact O-NE2 3.34Å; H434-T436 VanDerWaalsContact C-N 3.31Å; H434-T436 PolarHBondContact O-N 3.15Å
435	G	74.4	Confident	85.4	Confident	5 Å²	5	25.5 Å²	25.5	5%	0.052	12%	0.124	C	C	.	.	S	Bend	trans	79.2	13.7	175.3	0	0	0	0	0	114.3	S118 E437 P438	S118-G435 WeakPolarHBondContact CB-O 3.48Å; G435-E437 VanDerWaalsContact C-N 3.31Å; G435-E437 VanDerWaalsContact C-OE2 3.23Å; G435-E437 WeakPolarHBondContact CA-OE2 3.4Å; G435-E437 PolarHBondContact N-OE1 2.92Å; G435-P438 WeakPolarHBondContact O-CD 3.46Å
436	T	82.6	Confident	85.3	Confident	1 Å²	1	27.9 Å²	27.9	1%	0.006	14%	0.135	C	C	.	.			trans	-84.3	-8.4	179.6	60	0	0	0	0	112.5	I292 F426 H434 I439 F440	I292-T436 HydrophobicContact CD1-CG2 3.77Å; F426-T436 HydrophobicContact CE1-CG2 4.28Å; F426-T436 WeakPolarHBondContact CE1-OG1 3.22Å; H434-T436 VanDerWaalsContact C-N 3.31Å; H434-T436 PolarHBondContact O-N 3.15Å; T436-I439 WeakPolarHBondContact O-CA 3.29Å; T436-I439 VanDerWaalsContact O-CB 3.3Å; T436-I439 WeakPolarHBondContact O-CB 3.34Å; T436-I439 PolarHBondContact O-N 3.16Å; T436-F440 WeakPolarHBondContact O-CD2 3.48Å; T436-F440 PolarHBondContact O-N 2.89Å
437	E	86.6	Confident	85.2	Confident	2 Å²	2	29.6 Å²	29.6	1%	0.009	14%	0.142	C	C	.	.	H	α-helix	trans	-54.7	-47.6	-175.8	-41.2	74.5	-157	0	0	112	R127 F184 I423 H427 G435 I439 F440 F441	R127-E437 IonicContact CZ-OE2 3.97Å; R127-E437 IonicContact NH2-OE2 3.53Å; R127-E437 PolarHBondContact NH2-OE2 3.46Å; F184-E437 HydrophobicContact CE2-CB 4.35Å; F184-E437 HydrophobicContact CE2-CG 4.46Å; F184-E437 HydrophobicContact CZ-CG 4.2Å; I423-E437 HydrophobicContact CG2-CB 4.34Å; I423-E437 HydrophobicContact CG2-CG 3.88Å; H427-E437 IonicContact CE1-OE1 2.69Å; H427-E437 PolarHBondContact CE1-OE1 3.07Å; H427-E437 IonicContact NE2-OE1 2.91Å; H427-E437 PolarHBondContact NE2-OE1 3.49Å; G435-E437 VanDerWaalsContact C-N 3.31Å; G435-E437 VanDerWaalsContact C-OE2 3.23Å; G435-E437 WeakPolarHBondContact CA-OE2 3.4Å; G435-E437 PolarHBondContact N-OE1 2.92Å; E437-I439 PolarHBondContact O-N 2.92Å; E437-F440 WeakPolarHBondContact O-CB 3.27Å; E437-F440 PolarHBondContact O-N 3.2Å; E437-F440 VanDerWaalsContact O-N 3.11Å; E437-F441 VanDerWaalsContact O-CD2 3.27Å; E437-F441 WeakPolarHBondContact O-CD2 3.48Å; E437-F441 PolarHBondContact O-N 3.15Å
438	P	86.6	Confident	85.4	Confident	0 Å²	0	30.7 Å²	30.7	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-60.3	-29	177.1	-23.1	35	0	0	0	113.8	I117 A180 G435 S442	I117-P438 HydrophobicContact CB-CB 4.15Å; I117-P438 HydrophobicContact CB-CG 4.38Å; I117-P438 HydrophobicContact CG2-CB 3.93Å; I117-P438 HydrophobicContact CG2-CG 3.69Å; A180-P438 HydrophobicContact CB-CB 4.43Å; A180-P438 HydrophobicContact CB-CG 4.36Å; G435-P438 WeakPolarHBondContact O-CD 3.46Å; P438-S442 WeakPolarHBondContact O-CB 3.48Å; P438-S442 PolarHBondContact O-N 2.67Å; P438-S442 PolarHBondContact O-OG 2.95Å; P438-S442 VanDerWaalsContact O-OG 3.13Å
439	I	89.3	Confident	85.3	Confident	8 Å²	8	29.8 Å²	29.8	4%	0.041	14%	0.144	C	C	.	.	H	α-helix	trans	-70.7	-40.6	177	-55.3	175.3	0	0	0	110.3	V301 T436 E437 F441 S442 F443	V301-I439 HydrophobicContact CG2-CG2 4.09Å; T436-I439 WeakPolarHBondContact O-CA 3.29Å; T436-I439 VanDerWaalsContact O-CB 3.3Å; T436-I439 WeakPolarHBondContact O-CB 3.34Å; T436-I439 PolarHBondContact O-N 3.16Å; E437-I439 PolarHBondContact O-N 2.92Å; I439-F441 VanDerWaalsContact C-N 3.34Å; I439-F441 PolarHBondContact O-N 3.31Å; I439-S442 WeakPolarHBondContact CA-OG 3.48Å; I439-S442 PolarHBondContact O-OG 2.69Å; I439-S442 VanDerWaalsContact O-OG 3.1Å; I439-F443 WeakPolarHBondContact O-CB 3.48Å; I439-F443 PolarHBondContact O-N 3.18Å
440	F	91.5	Very high	85.4	Confident	0 Å²	0	30.4 Å²	30.4	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-60.6	-43.7	175.4	-80.7	-89.1	0	0	0	111.9	V301 Y307 L419 V422 I423 F426 T436 E437 Y444	V301-F440 HydrophobicContact CB-CE1 4.5Å; V301-F440 HydrophobicContact CB-CZ 4.28Å; V301-F440 HydrophobicContact CG1-CD1 3.87Å; V301-F440 HydrophobicContact CG1-CD2 4.47Å; V301-F440 HydrophobicContact CG1-CE1 3.71Å; V301-F440 HydrophobicContact CG1-CE2 4.35Å; V301-F440 HydrophobicContact CG1-CG 4.22Å; V301-F440 HydrophobicContact CG1-CZ 3.95Å; V301-F440 HydrophobicContact CG2-CD2 4.07Å; V301-F440 HydrophobicContact CG2-CE1 4.43Å; V301-F440 HydrophobicContact CG2-CE2 3.66Å; V301-F440 HydrophobicContact CG2-CZ 3.84Å; Y307-F440 HydrophobicContact CD1-CD1 4.31Å; Y307-F440 HydrophobicContact CD1-CE1 4.16Å; Y307-F440 AromaticContact CD2-CD1 3.46Å; Y307-F440 HydrophobicContact CD2-CD1 3.46Å; Y307-F440 VanDerWaalsContact CD2-CD1 3.46Å; Y307-F440 AromaticContact CD2-CE1 3.74Å; Y307-F440 HydrophobicContact CD2-CE1 3.74Å; Y307-F440 HydrophobicContact CE1-CD1 4.23Å; Y307-F440 HydrophobicContact CE1-CE1 4.47Å; Y307-F440 HydrophobicContact CE2-CB 4.4Å; Y307-F440 AromaticContact CE2-CD1 3.38Å; Y307-F440 HydrophobicContact CE2-CD1 3.38Å; Y307-F440 HydrophobicContact CE2-CE1 4.09Å; Y307-F440 HydrophobicContact CE2-CG 4.34Å; Y307-F440 AromaticContact CG-CD1 3.9Å; Y307-F440 HydrophobicContact CG-CD1 3.9Å; Y307-F440 AromaticContact CG-CE1 3.73Å; Y307-F440 HydrophobicContact CG-CE1 3.73Å; Y307-F440 AromaticContact CZ-CD1 3.72Å; Y307-F440 PolarHBondContact OH-O 3.28Å; L419-F440 HydrophobicContact CD1-CB 4.44Å; V422-F440 HydrophobicContact CG1-CE1 4.35Å; I423-F440 HydrophobicContact CD1-CB 3.82Å; I423-F440 HydrophobicContact CD1-CG 4.27Å; I423-F440 HydrophobicContact CG1-CB 3.85Å; I423-F440 HydrophobicContact CG1-CD1 4.08Å; I423-F440 HydrophobicContact CG1-CD2 4.02Å; I423-F440 HydrophobicContact CG1-CG 3.74Å; F426-F440 HydrophobicContact CB-CE2 4.47Å; F426-F440 HydrophobicContact CB-CZ 3.92Å; F426-F440 AromaticContact CD1-CE2 3.65Å; F426-F440 HydrophobicContact CD1-CE2 3.65Å; F426-F440 AromaticContact CD1-CZ 3.75Å; F426-F440 HydrophobicContact CD1-CZ 3.75Å; F426-F440 AromaticContact CD2-CZ 3.86Å; F426-F440 HydrophobicContact CD2-CZ 3.86Å; F426-F440 AromaticContact CE1-CE2 4Å; F426-F440 HydrophobicContact CE1-CE2 4Å; F426-F440 HydrophobicContact CE1-CZ 4.25Å; F426-F440 HydrophobicContact CE2-CZ 4.31Å; F426-F440 AromaticContact CG-CE2 3.98Å; F426-F440 HydrophobicContact CG-CE2 3.98Å; F426-F440 AromaticContact CG-CZ 3.56Å; F426-F440 HydrophobicContact CG-CZ 3.56Å; F426-F440 HydrophobicContact CZ-CZ 4.49Å; T436-F440 WeakPolarHBondContact O-CD2 3.48Å; T436-F440 PolarHBondContact O-N 2.89Å; E437-F440 WeakPolarHBondContact O-CB 3.27Å; E437-F440 PolarHBondContact O-N 3.2Å; E437-F440 VanDerWaalsContact O-N 3.11Å; F440-Y444 WeakPolarHBondContact O-CB 3.32Å; F440-Y444 PolarHBondContact O-N 3.18Å
441	F	90.9	Very high	85.7	Confident	2 Å²	2	27.2 Å²	27.2	1%	0.009	13%	0.132	C	C	.	.	H	α-helix	trans	-69.9	-47	178.2	-78.5	-78.6	0	0	0	112.3	A180 M183 W416 L419 I423 E437 I439 F443 Y444 V445	A180-F441 HydrophobicContact CB-CD2 3.96Å; A180-F441 HydrophobicContact CB-CG 4.45Å; M183-F441 HydrophobicContact CG-CE2 3.73Å; M183-F441 HydrophobicContact CG-CZ 4.14Å; W416-F441 HydrophobicContact CE3-CD1 4Å; W416-F441 AromaticContact CE3-CE1 3.95Å; W416-F441 HydrophobicContact CE3-CE1 3.95Å; W416-F441 AromaticContact CZ3-CD1 3.72Å; W416-F441 HydrophobicContact CZ3-CD1 3.72Å; W416-F441 HydrophobicContact CZ3-CE1 4.12Å; L419-F441 HydrophobicContact CD2-CD1 3.38Å; L419-F441 HydrophobicContact CD2-CE1 3.56Å; L419-F441 HydrophobicContact CD2-CG 3.98Å; L419-F441 HydrophobicContact CD2-CZ 4.23Å; L419-F441 HydrophobicContact CG-CD1 4.43Å; L419-F441 HydrophobicContact CG-CE1 4.26Å; I423-F441 HydrophobicContact CD1-CD2 4.09Å; I423-F441 HydrophobicContact CD1-CE2 3.58Å; I423-F441 HydrophobicContact CD1-CZ 4.24Å; E437-F441 VanDerWaalsContact O-CD2 3.27Å; E437-F441 WeakPolarHBondContact O-CD2 3.48Å; E437-F441 PolarHBondContact O-N 3.15Å; I439-F441 VanDerWaalsContact C-N 3.34Å; I439-F441 PolarHBondContact O-N 3.31Å; F441-F443 VanDerWaalsContact C-N 3.32Å; F441-F443 PolarHBondContact O-N 3.3Å; F441-Y444 PolarHBondContact O-N 2.68Å; F441-V445 WeakPolarHBondContact O-CG2 3.38Å; F441-V445 PolarHBondContact O-N 3.31Å
442	S	90.3	Very high	86.3	Confident	1 Å²	1	26.1 Å²	26.1	1%	0.007	13%	0.126	C	C	.	.	H	α-helix	trans	-62.3	-40.4	-179	63.3	0	0	0	0	112.6	D110 P438 I439 V445 F446	D110-S442 WeakPolarHBondContact O-CB 3.3Å; P438-S442 WeakPolarHBondContact O-CB 3.48Å; P438-S442 PolarHBondContact O-N 2.67Å; P438-S442 PolarHBondContact O-OG 2.95Å; P438-S442 VanDerWaalsContact O-OG 3.13Å; I439-S442 WeakPolarHBondContact CA-OG 3.48Å; I439-S442 PolarHBondContact O-OG 2.69Å; I439-S442 VanDerWaalsContact O-OG 3.1Å; S442-V445 PolarHBondContact O-N 2.92Å; S442-F446 WeakPolarHBondContact O-CB 3.41Å; S442-F446 PolarHBondContact O-N 3.33Å
443	F	90	Very high	87	Confident	25 Å²	25	22.3 Å²	22.3	11%	0.11	12%	0.121	C	C	.	.	H	α-helix	trans	-72.6	-32.3	-179.4	-157.1	-112.2	0	0	0	112.5	L298 M302 Y307 I311 I439 F441 F446 F447	L298-F443 HydrophobicContact CD1-CD2 3.7Å; L298-F443 HydrophobicContact CD1-CE2 3.71Å; L298-F443 HydrophobicContact CD1-CG 4.18Å; L298-F443 HydrophobicContact CD1-CZ 4.16Å; M302-F443 HydrophobicContact CE-CE1 4.04Å; M302-F443 HydrophobicContact CG-CD1 4.34Å; M302-F443 HydrophobicContact CG-CE1 3.75Å; M302-F443 HydrophobicContact CG-CZ 4.24Å; M302-F443 HydrophobicContact SD-CD1 3.7Å; M302-F443 HydrophobicContact SD-CE1 3.19Å; M302-F443 WeakPolarHBondContact SD-CE1 3.01Å; M302-F443 HydrophobicContact SD-CZ 4.15Å; Y307-F443 HydrophobicContact CE1-CD1 4.25Å; I311-F443 HydrophobicContact CD1-CD1 4.48Å; I439-F443 WeakPolarHBondContact O-CB 3.48Å; I439-F443 PolarHBondContact O-N 3.18Å; F441-F443 VanDerWaalsContact C-N 3.32Å; F441-F443 PolarHBondContact O-N 3.3Å; F443-F446 HydrophobicContact CD2-CD1 4.12Å; F443-F446 AromaticContact CE2-CD1 3.89Å; F443-F446 HydrophobicContact CE2-CD1 3.89Å; F443-F446 HydrophobicContact CE2-CE1 4.22Å; F443-F446 HydrophobicContact CZ-CD1 4.41Å; F443-F447 AromaticContact CD1-CD2 3.83Å; F443-F447 HydrophobicContact CD1-CD2 3.83Å; F443-F447 AromaticContact CD1-CE2 3.33Å; F443-F447 HydrophobicContact CD1-CE2 3.33Å; F443-F447 HydrophobicContact CD1-CZ 4.2Å; F443-F447 AromaticContact CE1-CD2 3.85Å; F443-F447 HydrophobicContact CE1-CD2 3.85Å; F443-F447 AromaticContact CE1-CE2 2.94Å; F443-F447 HydrophobicContact CE1-CE2 2.94Å; F443-F447 AromaticContact CE1-CZ 3.37Å; F443-F447 HydrophobicContact CE1-CZ 3.37Å; F443-F447 HydrophobicContact CG-CE2 4.33Å; F443-F447 AromaticContact CZ-CE2 3.68Å; F443-F447 HydrophobicContact CZ-CE2 3.68Å; F443-F447 AromaticContact CZ-CZ 3.69Å; F443-F447 HydrophobicContact CZ-CZ 3.69Å; F443-F447 WeakPolarHBondContact O-CD2 3.02Å; F443-F447 PolarHBondContact O-N 2.78Å; F443-F447 VanDerWaalsContact O-N 3.14Å
444	Y	92.1	Very high	87.9	Confident	13 Å²	13	22.7 Å²	22.7	5%	0.051	13%	0.126	C	C	.	.	H	α-helix	trans	-60.9	-49.5	168.3	170.6	-98.8	0	0	0	111.3	I311 F314 P415 W416 L419 F440 F441 F446 F447 T448	I311-Y444 HydrophobicContact CG1-CD2 4.12Å; F314-Y444 HydrophobicContact CB-CE2 4.22Å; P415-Y444 HydrophobicContact CB-CE1 4.38Å; P415-Y444 HydrophobicContact CB-CE2 3.74Å; P415-Y444 VanDerWaalsContact CB-CZ 3.46Å; P415-Y444 WeakPolarHBondContact CB-OH 3.47Å; P415-Y444 VanDerWaalsContact CG-OH 3.31Å; P415-Y444 WeakPolarHBondContact CG-OH 3.36Å; W416-Y444 HydrophobicContact CD2-CE1 4.05Å; W416-Y444 AromaticContact CE2-CE1 3.66Å; W416-Y444 HydrophobicContact CE3-CD1 4.44Å; W416-Y444 HydrophobicContact CE3-CE1 4.32Å; W416-Y444 HydrophobicContact CH2-CD1 4.05Å; W416-Y444 AromaticContact CH2-CE1 3.98Å; W416-Y444 HydrophobicContact CH2-CE1 3.98Å; W416-Y444 HydrophobicContact CZ2-CD1 4.2Å; W416-Y444 AromaticContact CZ2-CE1 3.65Å; W416-Y444 HydrophobicContact CZ2-CE1 3.65Å; W416-Y444 HydrophobicContact CZ3-CD1 4.16Å; W416-Y444 HydrophobicContact CZ3-CE1 4.28Å; L419-Y444 HydrophobicContact CD2-CD1 4.36Å; L419-Y444 HydrophobicContact CD2-CG 4.19Å; F440-Y444 WeakPolarHBondContact O-CB 3.32Å; F440-Y444 PolarHBondContact O-N 3.18Å; F441-Y444 PolarHBondContact O-N 2.68Å; Y444-F446 PolarHBondContact O-N 3.17Å; Y444-F447 PolarHBondContact O-N 3.41Å; Y444-T448 HydrophobicContact CD1-CG2 4.48Å; Y444-T448 HydrophobicContact CE1-CG2 3.88Å; Y444-T448 HydrophobicContact CE2-CG2 3.93Å; Y444-T448 PolarHBondContact O-N 3.05Å
445	V	90.3	Very high	88.9	Confident	2 Å²	2	21.8 Å²	21.8	1%	0.012	12%	0.122	C	C	.	.	H	α-helix	trans	-60.4	-45.5	179	177.4	0	0	0	0	110.9	D110 W416 F441 S442 F447 T448 K449	D110-V445 WeakPolarHBondContact OD2-CG1 3.34Å; W416-V445 HydrophobicContact CH2-CG2 3.66Å; W416-V445 HydrophobicContact CZ2-CG2 4.46Å; W416-V445 HydrophobicContact CZ3-CG2 4.43Å; F441-V445 WeakPolarHBondContact O-CG2 3.38Å; F441-V445 PolarHBondContact O-N 3.31Å; S442-V445 PolarHBondContact O-N 2.92Å; V445-F447 VanDerWaalsContact C-N 3.31Å; V445-F447 PolarHBondContact O-N 3.05Å; V445-T448 WeakPolarHBondContact CA-OG1 3.4Å; V445-T448 PolarHBondContact O-N 3.35Å; V445-T448 PolarHBondContact O-OG1 2.88Å; V445-K449 HydrophobicContact CG1-CD 4.46Å; V445-K449 PolarHBondContact O-N 2.96Å
446	F	90.9	Very high	89.4	Confident	51 Å²	51	26.6 Å²	26.6	22%	0.224	15%	0.146	C	C	.	.	H	α-helix	trans	-50.5	-49.1	173.7	165.7	-106.7	0	0	0	112.3	A107 D110 S442 F443 Y444 T448 K449 F450	A107-F446 HydrophobicContact CB-CD2 4.17Å; A107-F446 HydrophobicContact CB-CE2 4.27Å; A107-F446 WeakPolarHBondContact O-CD2 3.48Å; D110-F446 HydrophobicContact CB-CB 4.42Å; S442-F446 WeakPolarHBondContact O-CB 3.41Å; S442-F446 PolarHBondContact O-N 3.33Å; F443-F446 HydrophobicContact CD2-CD1 4.12Å; F443-F446 AromaticContact CE2-CD1 3.89Å; F443-F446 HydrophobicContact CE2-CD1 3.89Å; F443-F446 HydrophobicContact CE2-CE1 4.22Å; F443-F446 HydrophobicContact CZ-CD1 4.41Å; Y444-F446 PolarHBondContact O-N 3.17Å; F446-T448 PolarHBondContact O-N 3.49Å; F446-K449 PolarHBondContact O-N 3.49Å; F446-F450 WeakPolarHBondContact O-CB 3.42Å; F446-F450 PolarHBondContact O-N 2.87Å
447	F	91.1	Very high	89.6	Confident	38 Å²	38	28 Å²	28	17%	0.167	16%	0.161	C	C	.	.	H	α-helix	trans	-66.5	-35.2	179.2	-83.1	-57.3	0	0	0	113.6	I311 L315 F443 Y444 V445 F450 A451	I311-F447 HydrophobicContact CD1-CD2 4.01Å; I311-F447 HydrophobicContact CD1-CE2 4.31Å; I311-F447 HydrophobicContact CG2-CD2 3.42Å; I311-F447 VanDerWaalsContact CG2-CD2 3.42Å; I311-F447 HydrophobicContact CG2-CE2 3.43Å; I311-F447 VanDerWaalsContact CG2-CE2 3.43Å; I311-F447 HydrophobicContact CG2-CG 4.17Å; I311-F447 HydrophobicContact CG2-CZ 4.31Å; L315-F447 HydrophobicContact CD1-CB 3.94Å; L315-F447 HydrophobicContact CD1-CD1 4.07Å; L315-F447 HydrophobicContact CD1-CG 4.36Å; L315-F447 VanDerWaalsContact CD1-O 3.25Å; L315-F447 WeakPolarHBondContact CD1-O 3.25Å; L315-F447 HydrophobicContact CD2-CD1 4.5Å; F443-F447 AromaticContact CD1-CD2 3.83Å; F443-F447 HydrophobicContact CD1-CD2 3.83Å; F443-F447 AromaticContact CD1-CE2 3.33Å; F443-F447 HydrophobicContact CD1-CE2 3.33Å; F443-F447 HydrophobicContact CD1-CZ 4.2Å; F443-F447 AromaticContact CE1-CD2 3.85Å; F443-F447 HydrophobicContact CE1-CD2 3.85Å; F443-F447 AromaticContact CE1-CE2 2.94Å; F443-F447 HydrophobicContact CE1-CE2 2.94Å; F443-F447 AromaticContact CE1-CZ 3.37Å; F443-F447 HydrophobicContact CE1-CZ 3.37Å; F443-F447 HydrophobicContact CG-CE2 4.33Å; F443-F447 AromaticContact CZ-CE2 3.68Å; F443-F447 HydrophobicContact CZ-CE2 3.68Å; F443-F447 AromaticContact CZ-CZ 3.69Å; F443-F447 HydrophobicContact CZ-CZ 3.69Å; F443-F447 WeakPolarHBondContact O-CD2 3.02Å; F443-F447 PolarHBondContact O-N 2.78Å; F443-F447 VanDerWaalsContact O-N 3.14Å; Y444-F447 PolarHBondContact O-N 3.41Å; V445-F447 VanDerWaalsContact C-N 3.31Å; V445-F447 PolarHBondContact O-N 3.05Å; F447-F450 PolarHBondContact O-N 3.49Å; F447-A451 WeakPolarHBondContact O-CB 3.47Å; F447-A451 PolarHBondContact O-N 3.41Å
448	T	90.1	Very high	89.9	Confident	36 Å²	36	31.1 Å²	31.1	22%	0.221	18%	0.177	C	C	.	.	H	α-helix	trans	-65	-40.6	175	59.9	0	0	0	0	111.7	Y444 V445 F446 A451 S452	Y444-T448 HydrophobicContact CD1-CG2 4.48Å; Y444-T448 HydrophobicContact CE1-CG2 3.88Å; Y444-T448 HydrophobicContact CE2-CG2 3.93Å; Y444-T448 PolarHBondContact O-N 3.05Å; V445-T448 WeakPolarHBondContact CA-OG1 3.4Å; V445-T448 PolarHBondContact O-N 3.35Å; V445-T448 PolarHBondContact O-OG1 2.88Å; F446-T448 PolarHBondContact O-N 3.49Å; T448-A451 PolarHBondContact O-N 3Å; T448-S452 PolarHBondContact O-N 3.35Å
449	K	88.5	Confident	90	Very high	29 Å²	29	31.5 Å²	31.5	13%	0.126	18%	0.18	C	C	.	.	H	α-helix	trans	-67.8	-38.8	173.6	-66.8	-174.5	-173.3	165.1	0	112.2	D106 D110 V445 F446 A451 S452 G453	D106-K449 PolarHBondContact O-NZ 3.35Å; D106-K449 IonicContact OD1-NZ 2.83Å; D106-K449 PolarHBondContact OD1-NZ 3.19Å; D106-K449 WeakPolarHBondContact OD2-CD 3.44Å; D106-K449 WeakPolarHBondContact OD2-CE 3.25Å; D106-K449 IonicContact OD2-NZ 3.93Å; D106-K449 PolarHBondContact OD2-NZ 2.81Å; D110-K449 IonicContact OD1-NZ 3.13Å; D110-K449 PolarHBondContact OD1-NZ 2.86Å; D110-K449 WeakPolarHBondContact OD2-CD 3.45Å; D110-K449 WeakPolarHBondContact OD2-CE 3.47Å; D110-K449 IonicContact OD2-NZ 3.99Å; D110-K449 PolarHBondContact OD2-NZ 3.46Å; V445-K449 HydrophobicContact CG1-CD 4.46Å; V445-K449 PolarHBondContact O-N 2.96Å; F446-K449 PolarHBondContact O-N 3.49Å; K449-A451 VanDerWaalsContact C-N 3.35Å; K449-A451 PolarHBondContact O-N 3.49Å; K449-S452 WeakPolarHBondContact O-CB 3.35Å; K449-S452 PolarHBondContact O-N 2.92Å; K449-G453 PolarHBondContact O-N 3.02Å
450	F	89.7	Confident	89.9	Confident	107 Å²	107	34.9 Å²	34.9	47%	0.469	20%	0.201	S	C	.	.	H	α-helix	trans	-59	-45.6	172.6	178.7	-102.9	0	0	0	111.4	L315 F446 F447 S452 G453 V454	L315-F450 HydrophobicContact CD1-CD1 4.26Å; F446-F450 WeakPolarHBondContact O-CB 3.42Å; F446-F450 PolarHBondContact O-N 2.87Å; F447-F450 PolarHBondContact O-N 3.49Å; F450-S452 VanDerWaalsContact C-N 3.33Å; F450-S452 PolarHBondContact O-N 3.29Å; F450-G453 PolarHBondContact O-N 2.96Å; F450-V454 HydrophobicContact CD1-CG2 4.22Å; F450-V454 HydrophobicContact CD2-CG2 4.39Å; F450-V454 HydrophobicContact CE1-CG2 3.8Å; F450-V454 HydrophobicContact CE2-CG2 3.99Å; F450-V454 HydrophobicContact CG-CG2 4.5Å; F450-V454 HydrophobicContact CZ-CG2 3.67Å; F450-V454 VanDerWaalsContact O-CG2 3.32Å; F450-V454 WeakPolarHBondContact O-CG2 3.32Å; F450-V454 PolarHBondContact O-N 3.43Å
451	A	91.6	Very high	89.8	Confident	2 Å²	2	39.9 Å²	39.9	2%	0.017	23%	0.227	C	C	.	.	H	α-helix	trans	-60.4	-41.1	174.4	0	0	0	0	0	112.3	L315 L319 F447 T448 K449 V454 S455	L315-A451 HydrophobicContact CD1-CB 3.86Å; L319-A451 HydrophobicContact CB-CB 4.11Å; L319-A451 WeakPolarHBondContact CD1-O 3.43Å; F447-A451 WeakPolarHBondContact O-CB 3.47Å; F447-A451 PolarHBondContact O-N 3.41Å; T448-A451 PolarHBondContact O-N 3Å; K449-A451 VanDerWaalsContact C-N 3.35Å; K449-A451 PolarHBondContact O-N 3.49Å; A451-V454 PolarHBondContact O-N 3.36Å; A451-S455 WeakPolarHBondContact O-CB 3.31Å; A451-S455 PolarHBondContact O-N 2.99Å
452	S	89	Confident	89.9	Confident	37 Å²	37	41.7 Å²	41.7	26%	0.259	24%	0.24	S	C	.	.	H	α-helix	trans	-61.5	-45.4	174.8	-174.7	0	0	0	0	112	T448 K449 F450 S455 L456	T448-S452 PolarHBondContact O-N 3.35Å; K449-S452 WeakPolarHBondContact O-CB 3.35Å; K449-S452 PolarHBondContact O-N 2.92Å; F450-S452 VanDerWaalsContact C-N 3.33Å; F450-S452 PolarHBondContact O-N 3.29Å; S452-S455 WeakPolarHBondContact O-CB 3.38Å; S452-S455 PolarHBondContact O-N 3.37Å; S452-L456 PolarHBondContact O-N 2.76Å
453	G	87.4	Confident	89.8	Confident	45 Å²	45	42.1 Å²	42.1	46%	0.464	24%	0.242	S	C	.	.	H	α-helix	trans	-63.8	-42.7	176.2	0	0	0	0	0	113.3	K449 F450 L456 G457	K449-G453 PolarHBondContact O-N 3.02Å; F450-G453 PolarHBondContact O-N 2.96Å; G453-L456 PolarHBondContact O-N 2.92Å; G453-G457 PolarHBondContact O-N 3.33Å
454	V	91.3	Very high	89.7	Confident	49 Å²	49	46.5 Å²	46.5	30%	0.297	27%	0.267	S	S	.	.	H	α-helix	trans	-64	-42.3	175.3	171.8	0	0	0	0	111.1	L319 F450 A451 L456 G457 I458	L319-V454 HydrophobicContact CD1-CB 4.15Å; L319-V454 HydrophobicContact CD1-CG1 3.95Å; L319-V454 HydrophobicContact CD2-CG1 4.45Å; F450-V454 HydrophobicContact CD1-CG2 4.22Å; F450-V454 HydrophobicContact CD2-CG2 4.39Å; F450-V454 HydrophobicContact CE1-CG2 3.8Å; F450-V454 HydrophobicContact CE2-CG2 3.99Å; F450-V454 HydrophobicContact CG-CG2 4.5Å; F450-V454 HydrophobicContact CZ-CG2 3.67Å; F450-V454 VanDerWaalsContact O-CG2 3.32Å; F450-V454 WeakPolarHBondContact O-CG2 3.32Å; F450-V454 PolarHBondContact O-N 3.43Å; A451-V454 PolarHBondContact O-N 3.36Å; V454-L456 PolarHBondContact O-N 3.46Å; V454-G457 PolarHBondContact O-N 2.92Å; V454-I458 HydrophobicContact CG1-CD1 3.69Å; V454-I458 HydrophobicContact CG1-CG1 4.29Å; V454-I458 VanDerWaalsContact O-CG1 3.3Å; V454-I458 WeakPolarHBondContact O-CG1 3.2Å; V454-I458 PolarHBondContact O-N 3.04Å
455	S	92.1	Very high	89.7	Confident	4 Å²	4	53.3 Å²	53.3	3%	0.028	30%	0.297	C	S	.	.	H	α-helix	trans	-55.3	-51.1	174.3	173.3	0	0	0	0	111.5	M322 L323 A451 S452 G457 I458 S459	M322-S455 PolarHBondContact O-OG 3.19Å; L323-S455 WeakPolarHBondContact CA-OG 3.42Å; L323-S455 WeakPolarHBondContact CD2-OG 3.5Å; L323-S455 WeakPolarHBondContact CG-OG 3.18Å; L323-S455 PolarHBondContact N-OG 2.95Å; L323-S455 VanDerWaalsContact N-OG 3.1Å; A451-S455 WeakPolarHBondContact O-CB 3.31Å; A451-S455 PolarHBondContact O-N 2.99Å; S452-S455 WeakPolarHBondContact O-CB 3.38Å; S452-S455 PolarHBondContact O-N 3.37Å; S455-G457 VanDerWaalsContact C-N 3.34Å; S455-G457 PolarHBondContact O-N 3.5Å; S455-I458 PolarHBondContact O-N 2.99Å; S455-S459 WeakPolarHBondContact O-CB 3.38Å; S455-S459 PolarHBondContact O-N 3.18Å
456	L	86.6	Confident	89.7	Confident	106 Å²	106	53.5 Å²	53.5	56%	0.555	30%	0.298	S	S	*	.	H	α-helix	trans	-60.8	-43.3	179.5	-179.9	62.8	0	0	0	111.7	S452 G453 V454 S459 T460	S452-L456 PolarHBondContact O-N 2.76Å; G453-L456 PolarHBondContact O-N 2.92Å; V454-L456 PolarHBondContact O-N 3.46Å; L456-S459 PolarHBondContact O-N 2.87Å; L456-T460 WeakPolarHBondContact O-CB 3.18Å; L456-T460 PolarHBondContact O-N 3.33Å; L456-T460 PolarHBondContact O-OG1 3.48Å
457	G	86.2	Confident	89.6	Confident	30 Å²	30	52.8 Å²	52.8	31%	0.309	31%	0.306	S	S	.	.	H	α-helix	trans	-61.8	-47.6	177.1	0	0	0	0	0	112.7	G453 V454 S455 S459 T460 L461	G453-G457 PolarHBondContact O-N 3.33Å; V454-G457 PolarHBondContact O-N 2.92Å; S455-G457 VanDerWaalsContact C-N 3.34Å; S455-G457 PolarHBondContact O-N 3.5Å; G457-S459 PolarHBondContact O-N 3.17Å; G457-T460 PolarHBondContact O-N 3.37Å; G457-L461 WeakPolarHBondContact O-CB 3.28Å; G457-L461 WeakPolarHBondContact O-CG 3.2Å; G457-L461 PolarHBondContact O-N 3.38Å
458	I	92.9	Very high	89.3	Confident	69 Å²	69	53.9 Å²	53.9	35%	0.354	31%	0.309	S	S	.	.	H	α-helix	trans	-60.4	-46.4	176.6	-69.2	169.2	0	0	0	110.5	L323 V454 S455 S462 L486	L323-I458 HydrophobicContact CD2-CB 4.39Å; L323-I458 HydrophobicContact CD2-CG2 4.24Å; V454-I458 HydrophobicContact CG1-CD1 3.69Å; V454-I458 HydrophobicContact CG1-CG1 4.29Å; V454-I458 VanDerWaalsContact O-CG1 3.3Å; V454-I458 WeakPolarHBondContact O-CG1 3.2Å; V454-I458 PolarHBondContact O-N 3.04Å; S455-I458 PolarHBondContact O-N 2.99Å; I458-S462 WeakPolarHBondContact O-CB 3.09Å; I458-S462 PolarHBondContact O-N 3.47Å; I458-S462 PolarHBondContact O-OG 3.29Å; I458-L486 HydrophobicContact CG2-CD2 4.01Å
459	S	89.4	Confident	88.8	Confident	8 Å²	8	56.6 Å²	56.6	6%	0.056	32%	0.319	C	S	.	.	H	α-helix	trans	-59.3	-53.6	178.5	167.4	0	0	0	0	111.6	N327 S455 L456 G457 L461 S462 L463	N327-S459 PolarHBondContact ND2-OG 3.18Å; N327-S459 PolarHBondContact OD1-OG 2.8Å; S455-S459 WeakPolarHBondContact O-CB 3.38Å; S455-S459 PolarHBondContact O-N 3.18Å; L456-S459 PolarHBondContact O-N 2.87Å; G457-S459 PolarHBondContact O-N 3.17Å; S459-L461 PolarHBondContact O-N 2.9Å; S459-S462 PolarHBondContact O-N 2.69Å; S459-L463 WeakPolarHBondContact O-CB 3.38Å; S459-L463 VanDerWaalsContact O-CG 3.31Å; S459-L463 WeakPolarHBondContact O-CG 3.48Å; S459-L463 PolarHBondContact O-N 3.39Å
460	T	86.4	Confident	88.1	Confident	78 Å²	78	60.7 Å²	60.7	48%	0.479	35%	0.347	S	S	.	.	H	α-helix	trans	-61.9	-48.8	-175.5	-55.2	0	0	0	0	111.6	L456 G457 S462 L463 D464	L456-T460 WeakPolarHBondContact O-CB 3.18Å; L456-T460 PolarHBondContact O-N 3.33Å; L456-T460 PolarHBondContact O-OG1 3.48Å; G457-T460 PolarHBondContact O-N 3.37Å; T460-S462 PolarHBondContact O-N 3.01Å; T460-L463 PolarHBondContact O-N 3.07Å; T460-D464 WeakPolarHBondContact O-CB 3.35Å; T460-D464 PolarHBondContact O-N 3.04Å
461	L	88.9	Confident	87	Confident	105 Å²	105	61.1 Å²	61.1	55%	0.55	35%	0.345	S	S	.	.	H	α-helix	trans	-64	-41.6	179.4	-70.7	171.7	0	0	0	111.7	G457 S459 L463 D464 F465	G457-L461 WeakPolarHBondContact O-CB 3.28Å; G457-L461 WeakPolarHBondContact O-CG 3.2Å; G457-L461 PolarHBondContact O-N 3.38Å; S459-L461 PolarHBondContact O-N 2.9Å; L461-L463 VanDerWaalsContact C-N 3.32Å; L461-L463 PolarHBondContact O-N 2.74Å; L461-D464 PolarHBondContact O-N 3.42Å; L461-F465 HydrophobicContact CB-CE2 4.5Å; L461-F465 WeakPolarHBondContact O-CD2 3.37Å; L461-F465 PolarHBondContact O-N 3.33Å
462	S	92.6	Very high	85.9	Confident	40 Å²	40	61.5 Å²	61.5	28%	0.28	35%	0.349	S	S	.	.	H	α-helix	trans	-64.1	-39.9	179	-58.5	0	0	0	0	111.5	I458 S459 T460 A466	I458-S462 WeakPolarHBondContact O-CB 3.09Å; I458-S462 PolarHBondContact O-N 3.47Å; I458-S462 PolarHBondContact O-OG 3.29Å; S459-S462 PolarHBondContact O-N 2.69Å; T460-S462 PolarHBondContact O-N 3.01Å; S462-A466 WeakPolarHBondContact O-CB 3.44Å; S462-A466 PolarHBondContact O-N 3.16Å
463	L	89.1	Confident	85.2	Confident	11 Å²	11	61.9 Å²	61.9	6%	0.058	35%	0.351	C	S	.	.	H	α-helix	trans	-69.5	-37.9	177.1	-72	172.2	0	0	0	112.5	L330 S459 T460 L461 A466 G467 Y468 V479 T482 L483 L486	L330-L463 HydrophobicContact CD1-CD1 3.6Å; S459-L463 WeakPolarHBondContact O-CB 3.38Å; S459-L463 VanDerWaalsContact O-CG 3.31Å; S459-L463 WeakPolarHBondContact O-CG 3.48Å; S459-L463 PolarHBondContact O-N 3.39Å; T460-L463 PolarHBondContact O-N 3.07Å; L461-L463 VanDerWaalsContact C-N 3.32Å; L461-L463 PolarHBondContact O-N 2.74Å; L463-A466 WeakPolarHBondContact O-CB 3.1Å; L463-A466 PolarHBondContact O-N 2.96Å; L463-G467 PolarHBondContact O-N 3.07Å; L463-Y468 HydrophobicContact CB-CG 4.45Å; L463-Y468 HydrophobicContact CD2-CD2 4.5Å; L463-Y468 VanDerWaalsContact O-CB 3.27Å; L463-Y468 WeakPolarHBondContact O-CB 3.47Å; L463-Y468 PolarHBondContact O-N 3.33Å; L463-V479 HydrophobicContact CD2-CG1 4.1Å; L463-T482 HydrophobicContact CD2-CG2 4.43Å; L463-L483 HydrophobicContact CD2-CD2 3.86Å; L463-L483 HydrophobicContact CD2-CG 4.03Å; L463-L486 HydrophobicContact CG-CD1 4.47Å
464	D	87.3	Confident	84.8	Confident	117 Å²	117	63.7 Å²	63.7	63%	0.626	36%	0.357	S	S	*	.	H	α-helix	trans	-62.4	-48.2	174.6	-172.7	58.3	0	0	0	111.2	T460 L461 A466 G467	T460-D464 WeakPolarHBondContact O-CB 3.35Å; T460-D464 PolarHBondContact O-N 3.04Å; L461-D464 PolarHBondContact O-N 3.42Å; D464-A466 PolarHBondContact O-N 2.82Å; D464-G467 PolarHBondContact O-N 3.44Å
465	F	91.6	Very high	84.5	Confident	156 Å²	156	62.9 Å²	62.9	68%	0.684	35%	0.35	S	S	*	.	H	α-helix	trans	-62.4	-26.6	173.3	-72.9	-56	0	0	0	113.7	L461 R478	L461-F465 HydrophobicContact CB-CE2 4.5Å; L461-F465 WeakPolarHBondContact O-CD2 3.37Å; L461-F465 PolarHBondContact O-N 3.33Å; F465-R478 PolarHBondContact O-NH1 3.29Å
466	A	91.7	Very high	84.4	Confident	5 Å²	5	65 Å²	65	4%	0.041	36%	0.363	C	S	.	.	H	α-helix	trans	-75.9	-13.1	174.4	0	0	0	0	0	113.3	S462 L463 D464 R478 V479 T482	S462-A466 WeakPolarHBondContact O-CB 3.44Å; S462-A466 PolarHBondContact O-N 3.16Å; L463-A466 WeakPolarHBondContact O-CB 3.1Å; L463-A466 PolarHBondContact O-N 2.96Å; D464-A466 PolarHBondContact O-N 2.82Å; A466-R478 HydrophobicContact CB-CG 4.18Å; A466-V479 HydrophobicContact CB-CG2 3.96Å; A466-T482 HydrophobicContact CB-CG2 4.25Å; A466-T482 WeakPolarHBondContact CB-OG1 3.3Å
467	G	87.5	Confident	84.4	Confident	37 Å²	37	67 Å²	67	38%	0.381	37%	0.37	S	S	.	.	T	Hydrogen-bonded Turn	trans	80.8	37.8	-176.7	0	0	0	0	0	113.2	L463 D464 Q469	L463-G467 PolarHBondContact O-N 3.07Å; D464-G467 PolarHBondContact O-N 3.44Å; G467-Q469 PolarHBondContact O-N 3.01Å
468	Y	85.1	Confident	84.7	Confident	61 Å²	61	73.5 Å²	73.5	24%	0.239	39%	0.385	C	S	.	.			trans	-58.7	126.5	178.1	-179.8	-99.9	0	0	0	112	L330 Y334 L463 Q475 V479	L330-Y468 HydrophobicContact CD2-CE2 4.18Å; L330-Y468 WeakPolarHBondContact CD2-OH 3.39Å; Y334-Y468 HydrophobicContact CD2-CE2 4.31Å; Y334-Y468 AromaticContact CE2-CE2 3.75Å; Y334-Y468 HydrophobicContact CE2-CE2 3.75Å; Y334-Y468 PolarHBondContact OH-OH 3.11Å; L463-Y468 HydrophobicContact CB-CG 4.45Å; L463-Y468 HydrophobicContact CD2-CD2 4.5Å; L463-Y468 VanDerWaalsContact O-CB 3.27Å; L463-Y468 WeakPolarHBondContact O-CB 3.47Å; L463-Y468 PolarHBondContact O-N 3.33Å; Y468-Q475 HydrophobicContact CE2-CG 4.48Å; Y468-V479 HydrophobicContact CD2-CG1 3.85Å
469	Q	79.8	Confident	84.7	Confident	93 Å²	93	70.2 Å²	70.2	44%	0.435	37%	0.368	S	S	.	.			trans	-100.5	114.6	178.4	-64.2	-179.4	15.8	0	0	110.3	G467 R471 G472 Q475	G467-Q469 PolarHBondContact O-N 3.01Å; Q469-R471 PolarHBondContact O-N 3.38Å; Q469-G472 PolarHBondContact O-N 2.96Å; Q469-Q475 PolarHBondContact O-NE2 3.3Å
470	T	74.3	Confident	84.7	Confident	114 Å²	114	73.6 Å²	73.6	70%	0.699	38%	0.382	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.4	124.7	-179	-55.9	0	0	0	0	111.2	G472	T470-G472 VanDerWaalsContact C-N 3.26Å; T470-G472 PolarHBondContact O-N 3.32Å
471	R	67	Low	84.9	Confident	117 Å²	117	75.9 Å²	75.9	44%	0.442	39%	0.385	S	S	.	.	T	Hydrogen-bonded Turn	trans	63.8	16.4	179.2	-63.6	177.8	175.5	177.2	-1.8	116	D73 F226 Q469	D73-R471 IonicContact OD1-NH2 2.81Å; D73-R471 IonicContact OD2-NH2 3.06Å; F226-R471 HydrophobicContact CD2-CB 3.88Å; F226-R471 HydrophobicContact CE2-CB 4.3Å; F226-R471 PolarHBondContact N-O 2.84Å; Q469-R471 PolarHBondContact O-N 3.38Å
472	G	68.8	Low	85.2	Confident	9 Å²	9	71.9 Å²	71.9	9%	0.093	37%	0.365	C	S	.	.	B	Isolated β-bridge	trans	-66.6	137.8	173.2	0	0	0	0	0	113.3	R339 Q469 T470 S474	R339-G472 PolarHBondContact NH2-O 3.23Å; Q469-G472 PolarHBondContact O-N 2.96Å; T470-G472 VanDerWaalsContact C-N 3.26Å; T470-G472 PolarHBondContact O-N 3.32Å; G472-S474 PolarHBondContact O-N 2.76Å
473	C	73.2	Confident	85.1	Confident	46 Å²	46	70 Å²	70	31%	0.311	35%	0.352	S	S	.	.	S	Bend	trans	-67.4	-22.8	173.5	-57.4	0	0	0	0	112.2	C225 F226 R339	C225-C473 HydrophobicContact CB-CB 4.11Å; C225-C473 WeakPolarHBondContact CB-SG 3.43Å; C225-C473 WeakPolarHBondContact SG-CB 3.48Å; C225-C473 CovalentContact SG-SG 2.05Å; C225-C473 PolarHBondContact SG-SG 2.92Å; F226-C473 VanDerWaalsContact C-SG 3.56Å; F226-C473 PolarHBondContact O-SG 3.11Å; R339-C473 VanDerWaalsContact NH2-C 3.3Å; R339-C473 PolarHBondContact NH2-O 3.45Å
474	S	78.5	Confident	85.2	Confident	82 Å²	82	71.8 Å²	71.8	57%	0.573	36%	0.361	S	S	*	.	S	Bend	trans	-132.4	153.5	173.2	72.3	0	0	0	0	110.3	G472	G472-S474 PolarHBondContact O-N 2.76Å
475	Q	85.9	Confident	85.6	Confident	33 Å²	33	70.7 Å²	70.7	15%	0.154	35%	0.354	C	S	.	.			trans	-122	151.2	178.8	-66.7	-68.3	-20.7	0	0	109.7	Y334 Y468 Q469 V479	Y334-Q475 HydrophobicContact CD1-CB 4.29Å; Y334-Q475 HydrophobicContact CD1-CG 3.34Å; Y334-Q475 HydrophobicContact CD2-CG 4.11Å; Y334-Q475 HydrophobicContact CE1-CG 3.48Å; Y334-Q475 VanDerWaalsContact CE1-CG 3.48Å; Y334-Q475 HydrophobicContact CE2-CG 4.23Å; Y334-Q475 HydrophobicContact CG-CG 3.67Å; Y334-Q475 PolarHBondContact OH-NE2 2.98Å; Y468-Q475 HydrophobicContact CE2-CG 4.48Å; Q469-Q475 PolarHBondContact O-NE2 3.3Å; Q475-V479 HydrophobicContact CB-CB 4.14Å; Q475-V479 HydrophobicContact CB-CG1 4.13Å; Q475-V479 HydrophobicContact CG-CG1 4.37Å
476	P	88.8	Confident	85.7	Confident	47 Å²	47	63.7 Å²	63.7	31%	0.305	32%	0.324	S	S	.	.			trans	-57.3	147.4	172.1	-22.8	32	0	0	0	112.7	R478 V479 K480	P476-R478 PolarHBondContact O-N 3.42Å; P476-R478 VanDerWaalsContact O-N 3.09Å; P476-V479 HydrophobicContact CB-CG2 4.33Å; P476-V479 HydrophobicContact CG-CG2 4.28Å; P476-V479 VanDerWaalsContact O-CB 3.32Å; P476-V479 WeakPolarHBondContact O-CB 3.22Å; P476-V479 PolarHBondContact O-N 3.25Å; P476-K480 PolarHBondContact O-N 3.44Å
477	E	88.3	Confident	85.7	Confident	148 Å²	148	63.6 Å²	63.6	69%	0.692	32%	0.323	S	S	*	.	H	α-helix	trans	-54.6	-31.8	176.1	-77.3	-67.1	158.3	0	0	113.1	V479 K480 F481	E477-V479 VanDerWaalsContact C-N 3.28Å; E477-V479 PolarHBondContact O-N 2.98Å; E477-K480 PolarHBondContact O-N 2.91Å; E477-F481 PolarHBondContact O-N 3.42Å
478	R	92.5	Very high	86	Confident	168 Å²	168	62 Å²	62	63%	0.634	31%	0.306	S	S	*	.	H	α-helix	trans	-61	-35.9	175.3	-168.6	-171.6	-70.5	-177.6	1.7	112.4	F465 A466 P476 T482	F465-R478 PolarHBondContact O-NH1 3.29Å; A466-R478 HydrophobicContact CB-CG 4.18Å; P476-R478 PolarHBondContact O-N 3.42Å; P476-R478 VanDerWaalsContact O-N 3.09Å; R478-T482 WeakPolarHBondContact O-CB 3.28Å; R478-T482 PolarHBondContact O-N 3.2Å; R478-T482 PolarHBondContact O-OG1 3.04Å
479	V	91.4	Very high	86.4	Confident	0 Å²	0	63.3 Å²	63.3	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-67.4	-44.4	176.8	174.8	0	0	0	0	110.1	L463 A466 Y468 Q475 P476 E477 F481 T482 L483	L463-V479 HydrophobicContact CD2-CG1 4.1Å; A466-V479 HydrophobicContact CB-CG2 3.96Å; Y468-V479 HydrophobicContact CD2-CG1 3.85Å; Q475-V479 HydrophobicContact CB-CB 4.14Å; Q475-V479 HydrophobicContact CB-CG1 4.13Å; Q475-V479 HydrophobicContact CG-CG1 4.37Å; P476-V479 HydrophobicContact CB-CG2 4.33Å; P476-V479 HydrophobicContact CG-CG2 4.28Å; P476-V479 VanDerWaalsContact O-CB 3.32Å; P476-V479 WeakPolarHBondContact O-CB 3.22Å; P476-V479 PolarHBondContact O-N 3.25Å; E477-V479 VanDerWaalsContact C-N 3.28Å; E477-V479 PolarHBondContact O-N 2.98Å; V479-F481 PolarHBondContact O-N 3.05Å; V479-T482 WeakPolarHBondContact O-CB 3.24Å; V479-T482 PolarHBondContact O-N 3.4Å; V479-T482 VanDerWaalsContact O-N 3.16Å; V479-L483 HydrophobicContact CG1-CD1 4.06Å; V479-L483 HydrophobicContact CG1-CG 4.42Å; V479-L483 WeakPolarHBondContact O-CG 3.44Å; V479-L483 PolarHBondContact O-N 3.3Å
480	K	89.8	Confident	87.1	Confident	78 Å²	78	60.7 Å²	60.7	34%	0.339	31%	0.309	S	S	.	.	H	α-helix	trans	-59.2	-45.5	176.5	-172.8	178.4	178	-179.4	0	111.6	T335 P476 E477 T482 L483 N484	T335-K480 HydrophobicContact CG2-CG 4.02Å; P476-K480 PolarHBondContact O-N 3.44Å; E477-K480 PolarHBondContact O-N 2.91Å; K480-T482 VanDerWaalsContact C-N 3.34Å; K480-T482 PolarHBondContact O-N 2.97Å; K480-L483 PolarHBondContact O-N 3.32Å; K480-N484 PolarHBondContact O-N 3.27Å
481	F	91.9	Very high	88.2	Confident	127 Å²	127	55.2 Å²	55.2	56%	0.557	28%	0.276	S	S	*	.	H	α-helix	trans	-60.9	-42.4	174.3	179.6	-96.9	0	0	0	112.5	E477 V479 N484 M485	E477-F481 PolarHBondContact O-N 3.42Å; V479-F481 PolarHBondContact O-N 3.05Å; F481-N484 WeakPolarHBondContact O-CB 3.28Å; F481-N484 PolarHBondContact O-N 3.43Å; F481-M485 HydrophobicContact CD1-CG 4.47Å; F481-M485 HydrophobicContact CE1-CG 3.93Å; F481-M485 HydrophobicContact CE1-SD 3.62Å; F481-M485 HydrophobicContact CZ-CG 4.01Å; F481-M485 HydrophobicContact CZ-SD 3.83Å; F481-M485 PolarHBondContact O-N 3.35Å
482	T	93.6	Very high	89.6	Confident	21 Å²	21	50.6 Å²	50.6	13%	0.129	26%	0.259	C	S	.	.	H	α-helix	trans	-63.9	-44.7	178.9	-57.9	0	0	0	0	111.5	L463 A466 R478 V479 K480 N484 M485 L486	L463-T482 HydrophobicContact CD2-CG2 4.43Å; A466-T482 HydrophobicContact CB-CG2 4.25Å; A466-T482 WeakPolarHBondContact CB-OG1 3.3Å; R478-T482 WeakPolarHBondContact O-CB 3.28Å; R478-T482 PolarHBondContact O-N 3.2Å; R478-T482 PolarHBondContact O-OG1 3.04Å; V479-T482 WeakPolarHBondContact O-CB 3.24Å; V479-T482 PolarHBondContact O-N 3.4Å; V479-T482 VanDerWaalsContact O-N 3.16Å; K480-T482 VanDerWaalsContact C-N 3.34Å; K480-T482 PolarHBondContact O-N 2.97Å; T482-N484 VanDerWaalsContact C-N 3.34Å; T482-N484 PolarHBondContact O-N 3.3Å; T482-M485 PolarHBondContact O-N 2.95Å; T482-L486 HydrophobicContact CG2-CD1 3.98Å; T482-L486 HydrophobicContact CG2-CG 4.4Å; T482-L486 WeakPolarHBondContact O-CG 3.33Å; T482-L486 PolarHBondContact O-N 2.95Å
483	L	91.5	Very high	90.9	Very high	0 Å²	0	54.8 Å²	54.8	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-60.6	-42.1	174.7	-73.7	170.6	0	0	0	111.7	N327 L330 F331 L463 V479 K480 M485 L486 V487	N327-L483 HydrophobicContact CB-CD2 4.39Å; L330-L483 HydrophobicContact CB-CD1 4.17Å; L330-L483 HydrophobicContact CB-CD2 3.69Å; L330-L483 HydrophobicContact CD1-CD2 4.33Å; F331-L483 HydrophobicContact CD2-CB 4.47Å; L463-L483 HydrophobicContact CD2-CD2 3.86Å; L463-L483 HydrophobicContact CD2-CG 4.03Å; V479-L483 HydrophobicContact CG1-CD1 4.06Å; V479-L483 HydrophobicContact CG1-CG 4.42Å; V479-L483 WeakPolarHBondContact O-CG 3.44Å; V479-L483 PolarHBondContact O-N 3.3Å; K480-L483 PolarHBondContact O-N 3.32Å; L483-M485 PolarHBondContact O-N 3.42Å; L483-L486 PolarHBondContact O-N 3.21Å; L483-V487 WeakPolarHBondContact O-CB 3Å; L483-V487 WeakPolarHBondContact O-CG2 3.07Å; L483-V487 PolarHBondContact O-N 3.31Å
484	N	91.6	Very high	92.1	Very high	48 Å²	48	54 Å²	54	26%	0.257	28%	0.275	S	S	.	.	H	α-helix	trans	-57.6	-46.8	173.5	-79.9	-15.2	0	0	0	111.6	F331 T335 K480 F481 T482 T488	F331-N484 WeakPolarHBondContact CE2-OD1 3.24Å; T335-N484 VanDerWaalsContact CG2-OD1 3.29Å; T335-N484 WeakPolarHBondContact CG2-OD1 3.48Å; K480-N484 PolarHBondContact O-N 3.27Å; F481-N484 WeakPolarHBondContact O-CB 3.28Å; F481-N484 PolarHBondContact O-N 3.43Å; T482-N484 VanDerWaalsContact C-N 3.34Å; T482-N484 PolarHBondContact O-N 3.3Å; N484-T488 WeakPolarHBondContact O-CB 3.49Å; N484-T488 PolarHBondContact O-N 3.07Å; N484-T488 PolarHBondContact O-OG1 2.88Å
485	M	94.1	Very high	92.9	Very high	94 Å²	94	50.1 Å²	50.1	46%	0.463	25%	0.248	S	C	.	.	I	π-helix	trans	-64.2	-42.1	178	-75	-155.6	108.7	0	0	112.9	F481 T482 L483 M489 A490	F481-M485 HydrophobicContact CD1-CG 4.47Å; F481-M485 HydrophobicContact CE1-CG 3.93Å; F481-M485 HydrophobicContact CE1-SD 3.62Å; F481-M485 HydrophobicContact CZ-CG 4.01Å; F481-M485 HydrophobicContact CZ-SD 3.83Å; F481-M485 PolarHBondContact O-N 3.35Å; T482-M485 PolarHBondContact O-N 2.95Å; L483-M485 PolarHBondContact O-N 3.42Å; M485-M489 PolarHBondContact O-N 3.39Å; M485-A490 WeakPolarHBondContact O-CB 3.17Å; M485-A490 PolarHBondContact O-N 2.84Å
486	L	94	Very high	93.4	Very high	10 Å²	10	53.1 Å²	53.1	5%	0.052	27%	0.265	C	S	.	.	I	π-helix	trans	-68.6	-33.6	-178	-72.9	172.8	0	0	0	113.1	L323 I458 L463 T482 L483 P491	L323-L486 HydrophobicContact CD2-CD2 4.34Å; I458-L486 HydrophobicContact CG2-CD2 4.01Å; L463-L486 HydrophobicContact CG-CD1 4.47Å; T482-L486 HydrophobicContact CG2-CD1 3.98Å; T482-L486 HydrophobicContact CG2-CG 4.4Å; T482-L486 WeakPolarHBondContact O-CG 3.33Å; T482-L486 PolarHBondContact O-N 2.95Å; L483-L486 PolarHBondContact O-N 3.21Å; L486-P491 WeakPolarHBondContact O-CD 3.34Å; L486-P491 WeakPolarHBondContact O-CG 3.4Å
487	V	93	Very high	93.8	Very high	3 Å²	3	54.2 Å²	54.2	2%	0.018	27%	0.268	C	S	.	.	I	π-helix	trans	-90.5	-24.6	-178.2	174.2	0	0	0	0	112.5	V324 N327 F331 L384 V387 L483	V324-V487 HydrophobicContact CG1-CG1 4.4Å; N327-V487 HydrophobicContact CB-CG2 3.67Å; F331-V487 HydrophobicContact CB-CG2 3.97Å; F331-V487 HydrophobicContact CD2-CB 4.02Å; F331-V487 HydrophobicContact CD2-CG1 4.2Å; F331-V487 HydrophobicContact CD2-CG2 4.01Å; F331-V487 HydrophobicContact CE2-CB 4.38Å; F331-V487 HydrophobicContact CE2-CG1 4.39Å; F331-V487 HydrophobicContact CG-CB 4.42Å; F331-V487 HydrophobicContact CG-CG1 4.28Å; F331-V487 HydrophobicContact CG-CG2 4.13Å; L384-V487 WeakPolarHBondContact CD2-O 3.35Å; V387-V487 HydrophobicContact CG1-CG1 4.32Å; L483-V487 WeakPolarHBondContact O-CB 3Å; L483-V487 WeakPolarHBondContact O-CG2 3.07Å; L483-V487 PolarHBondContact O-N 3.31Å
488	T	92.7	Very high	94.1	Very high	4 Å²	4	47.1 Å²	47.1	3%	0.025	24%	0.235	C	C	.	.	I	π-helix	trans	-116.6	-73.2	-172.6	68.6	0	0	0	0	112.6	V387 A388 N484 P491 I492	V387-T488 HydrophobicContact CB-CG2 4.34Å; V387-T488 HydrophobicContact CG1-CG2 3.97Å; A388-T488 HydrophobicContact CB-CG2 3.8Å; N484-T488 WeakPolarHBondContact O-CB 3.49Å; N484-T488 PolarHBondContact O-N 3.07Å; N484-T488 PolarHBondContact O-OG1 2.88Å; T488-P491 WeakPolarHBondContact O-CD 3.25Å; T488-I492 WeakPolarHBondContact O-CD1 3.26Å; T488-I492 WeakPolarHBondContact O-CG1 3.48Å; T488-I492 PolarHBondContact O-N 3.03Å; T488-I492 VanDerWaalsContact O-N 3.08Å
489	M	93.4	Very high	94.2	Very high	87 Å²	87	40 Å²	40	43%	0.429	21%	0.209	S	C	.	.	I	π-helix	trans	-64.1	-47.2	-170.4	-65.1	-61.2	114.8	0	0	113.1	A388 M485 I492 V493	A388-M489 HydrophobicContact CB-CE 4.18Å; M485-M489 PolarHBondContact O-N 3.39Å; M489-I492 HydrophobicContact CE-CD1 4.05Å; M489-I492 PolarHBondContact O-N 2.83Å; M489-V493 WeakPolarHBondContact O-CG2 3.46Å; M489-V493 PolarHBondContact O-N 2.89Å; M489-V493 VanDerWaalsContact O-N 3.14Å
490	A	95.8	Very high	94.4	Very high	38 Å²	38	44.9 Å²	44.9	31%	0.314	24%	0.235	S	C	.	.	H	α-helix	trans	-63.2	-48.6	-179.2	0	0	0	0	0	112	M485 I492 V493 L494	M485-A490 WeakPolarHBondContact O-CB 3.17Å; M485-A490 PolarHBondContact O-N 2.84Å; A490-I492 VanDerWaalsContact C-N 3.35Å; A490-I492 PolarHBondContact O-N 2.05Å; A490-V493 PolarHBondContact O-N 3.49Å; A490-L494 WeakPolarHBondContact O-CG 3.31Å; A490-L494 PolarHBondContact O-N 3.28Å; A490-L494 VanDerWaalsContact O-N 3.09Å
491	P	96.4	Very high	94.6	Very high	0 Å²	0	42.9 Å²	42.9	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-57.6	-39.6	172.8	-30.3	37.9	0	0	0	114.3	A320 L323 V324 L384 L486 T488 V493 L494 I495	A320-P491 HydrophobicContact CB-CB 4.01Å; L323-P491 HydrophobicContact CB-CG 4.19Å; V324-P491 HydrophobicContact CG2-CB 3.82Å; V324-P491 HydrophobicContact CG2-CG 3.6Å; L384-P491 HydrophobicContact CD1-CB 3.9Å; L486-P491 WeakPolarHBondContact O-CD 3.34Å; L486-P491 WeakPolarHBondContact O-CG 3.4Å; T488-P491 WeakPolarHBondContact O-CD 3.25Å; P491-V493 PolarHBondContact O-N 3.33Å; P491-L494 PolarHBondContact O-N 3.37Å; P491-I495 WeakPolarHBondContact O-CB 3.32Å; P491-I495 WeakPolarHBondContact O-CD1 3.2Å; P491-I495 VanDerWaalsContact O-CG1 3.23Å; P491-I495 WeakPolarHBondContact O-CG1 3.4Å; P491-I495 PolarHBondContact O-N 2.69Å
492	I	96.4	Very high	94.7	Very high	19 Å²	19	37 Å²	37	10%	0.097	20%	0.202	C	C	.	.	H	α-helix	trans	-59.8	-47.6	177.1	-70.1	164	0	0	0	111	V381 L384 V385 T488 M489 A490 L494 I495 L496	V381-I492 HydrophobicContact CG1-CG2 4.19Å; L384-I492 HydrophobicContact CB-CD1 3.94Å; L384-I492 HydrophobicContact CB-CG1 3.82Å; L384-I492 HydrophobicContact CD1-CG1 3.88Å; V385-I492 HydrophobicContact CG2-CD1 3.83Å; T488-I492 WeakPolarHBondContact O-CD1 3.26Å; T488-I492 WeakPolarHBondContact O-CG1 3.48Å; T488-I492 PolarHBondContact O-N 3.03Å; T488-I492 VanDerWaalsContact O-N 3.08Å; M489-I492 HydrophobicContact CE-CD1 4.05Å; M489-I492 PolarHBondContact O-N 2.83Å; A490-I492 VanDerWaalsContact C-N 3.35Å; A490-I492 PolarHBondContact O-N 2.05Å; I492-L494 VanDerWaalsContact C-N 3.35Å; I492-L494 PolarHBondContact O-N 3.49Å; I492-I495 PolarHBondContact O-N 3.33Å; I492-L496 HydrophobicContact CG2-CD1 4.08Å; I492-L496 HydrophobicContact CG2-CG 4.48Å; I492-L496 VanDerWaalsContact O-CG 3.31Å; I492-L496 WeakPolarHBondContact O-CG 3.45Å; I492-L496 PolarHBondContact O-N 3.46Å
493	V	96.7	Very high	94.5	Very high	97 Å²	97	43.2 Å²	43.2	59%	0.588	23%	0.227	S	C	*	.	H	α-helix	trans	-62.1	-44	179.4	174	0	0	0	0	111.1	M489 A490 P491 L496 L497	M489-V493 WeakPolarHBondContact O-CG2 3.46Å; M489-V493 PolarHBondContact O-N 2.89Å; M489-V493 VanDerWaalsContact O-N 3.14Å; A490-V493 PolarHBondContact O-N 3.49Å; P491-V493 PolarHBondContact O-N 3.33Å; V493-L496 PolarHBondContact O-N 2.9Å; V493-L497 WeakPolarHBondContact O-CB 3.34Å; V493-L497 PolarHBondContact O-N 3.09Å
494	L	97.1	Very high	94.5	Very high	29 Å²	29	48.1 Å²	48.1	15%	0.152	25%	0.252	C	S	.	.	H	α-helix	trans	-64.2	-40.1	178.2	-68.9	171.4	0	0	0	112.2	F316 L319 A320 L323 A490 P491 I492 L497 G498	F316-L494 HydrophobicContact CD1-CD2 3.83Å; F316-L494 HydrophobicContact CE1-CD2 4.43Å; L319-L494 HydrophobicContact CB-CD1 4.46Å; L319-L494 HydrophobicContact CD2-CD1 4.03Å; L319-L494 HydrophobicContact CD2-CD2 4.09Å; L319-L494 HydrophobicContact CG-CD1 3.92Å; A320-L494 HydrophobicContact CB-CB 3.76Å; A320-L494 HydrophobicContact CB-CD1 4.28Å; L323-L494 HydrophobicContact CD1-CD1 3.7Å; A490-L494 WeakPolarHBondContact O-CG 3.31Å; A490-L494 PolarHBondContact O-N 3.28Å; A490-L494 VanDerWaalsContact O-N 3.09Å; P491-L494 PolarHBondContact O-N 3.37Å; I492-L494 VanDerWaalsContact C-N 3.35Å; I492-L494 PolarHBondContact O-N 3.49Å; L494-L497 PolarHBondContact O-N 3.31Å; L494-G498 PolarHBondContact O-N 3.46Å
495	I	96.4	Very high	94.6	Very high	2 Å²	2	46 Å²	46	1%	0.01	24%	0.241	C	C	.	.	H	α-helix	trans	-63	-46.5	175.2	-74.6	164	0	0	0	110.8	A320 I377 A380 V381 L384 P491 I492 L497 G498 L499	A320-I495 HydrophobicContact CB-CD1 4.17Å; A320-I495 HydrophobicContact CB-CG1 3.7Å; I377-I495 HydrophobicContact CG2-CG2 3.76Å; A380-I495 HydrophobicContact CB-CD1 3.91Å; V381-I495 HydrophobicContact CG2-CG2 3.91Å; L384-I495 HydrophobicContact CD1-CD1 3.76Å; P491-I495 WeakPolarHBondContact O-CB 3.32Å; P491-I495 WeakPolarHBondContact O-CD1 3.2Å; P491-I495 VanDerWaalsContact O-CG1 3.23Å; P491-I495 WeakPolarHBondContact O-CG1 3.4Å; P491-I495 PolarHBondContact O-N 2.69Å; I492-I495 PolarHBondContact O-N 3.33Å; I495-L497 VanDerWaalsContact C-N 3.31Å; I495-L497 PolarHBondContact O-N 3.1Å; I495-G498 PolarHBondContact O-N 3.13Å; I495-L499 HydrophobicContact CG2-CD1 3.98Å; I495-L499 HydrophobicContact CG2-CG 4.36Å; I495-L499 WeakPolarHBondContact O-CB 3.33Å; I495-L499 WeakPolarHBondContact O-CG 3.37Å; I495-L499 PolarHBondContact O-N 3.41Å
496	L	96.3	Very high	94.5	Very high	95 Å²	95	44.5 Å²	44.5	50%	0.497	24%	0.238	S	C	.	.	H	α-helix	trans	-62.2	-39.4	178.1	-68.8	175.1	0	0	0	111.9	I492 V493 L499 L500	I492-L496 HydrophobicContact CG2-CD1 4.08Å; I492-L496 HydrophobicContact CG2-CG 4.48Å; I492-L496 VanDerWaalsContact O-CG 3.31Å; I492-L496 WeakPolarHBondContact O-CG 3.45Å; I492-L496 PolarHBondContact O-N 3.46Å; V493-L496 PolarHBondContact O-N 2.9Å; L496-L499 PolarHBondContact O-N 3.25Å; L496-L500 PolarHBondContact O-N 2.88Å
497	L	96.3	Very high	94.3	Very high	70 Å²	70	44.1 Å²	44.1	37%	0.366	24%	0.236	S	C	.	.	H	α-helix	trans	-64.9	-43.4	174.9	-174.8	61.8	0	0	0	111.8	F316 V493 L494 I495 L500 L501	F316-L497 HydrophobicContact CD1-CD2 3.76Å; F316-L497 HydrophobicContact CD2-CD2 4.16Å; F316-L497 HydrophobicContact CD2-CG 4.26Å; F316-L497 HydrophobicContact CE1-CD2 3.52Å; F316-L497 HydrophobicContact CE2-CD2 3.94Å; F316-L497 HydrophobicContact CE2-CG 4.32Å; F316-L497 HydrophobicContact CG-CD2 4.08Å; F316-L497 HydrophobicContact CG-CG 4.36Å; F316-L497 HydrophobicContact CZ-CD2 3.62Å; F316-L497 HydrophobicContact CZ-CG 4.48Å; V493-L497 WeakPolarHBondContact O-CB 3.34Å; V493-L497 PolarHBondContact O-N 3.09Å; L494-L497 PolarHBondContact O-N 3.31Å; I495-L497 VanDerWaalsContact C-N 3.31Å; I495-L497 PolarHBondContact O-N 3.1Å; L497-L500 WeakPolarHBondContact O-CB 3.41Å; L497-L500 PolarHBondContact O-N 2.73Å; L497-L501 WeakPolarHBondContact O-CG 3.28Å; L497-L501 PolarHBondContact O-N 3.46Å; L497-L501 VanDerWaalsContact O-N 3.16Å
498	G	95.6	Very high	94.2	Very high	0 Å²	0	47.1 Å²	47.1	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-60.7	-44.9	174.3	0	0	0	0	0	112.7	L494 I495 L500 L501 F502	L494-G498 PolarHBondContact O-N 3.46Å; I495-G498 PolarHBondContact O-N 3.13Å; G498-L500 VanDerWaalsContact C-N 3.33Å; G498-L500 PolarHBondContact O-N 3.12Å; G498-L501 WeakPolarHBondContact O-CB 3.34Å; G498-L501 PolarHBondContact O-N 2.99Å; G498-L501 VanDerWaalsContact O-N 3.16Å; G498-F502 WeakPolarHBondContact O-CD2 3.39Å; G498-F502 PolarHBondContact O-N 3.23Å
499	L	94.9	Very high	94.1	Very high	18 Å²	18	51.5 Å²	51.5	9%	0.094	27%	0.272	C	S	.	.	H	α-helix	trans	-61.4	-38.4	175.6	-72.1	175.5	0	0	0	112.6	Y374 I377 I495 L496 L501 F502 K503	Y374-L499 HydrophobicContact CD1-CD2 3.95Å; Y374-L499 HydrophobicContact CE1-CB 4.47Å; Y374-L499 HydrophobicContact CE1-CD2 4.36Å; Y374-L499 PolarHBondContact OH-O 3.36Å; I377-L499 HydrophobicContact CB-CD2 3.99Å; I377-L499 HydrophobicContact CG2-CD2 3.98Å; I377-L499 HydrophobicContact CG2-CG 4.19Å; I495-L499 HydrophobicContact CG2-CD1 3.98Å; I495-L499 HydrophobicContact CG2-CG 4.36Å; I495-L499 WeakPolarHBondContact O-CB 3.33Å; I495-L499 WeakPolarHBondContact O-CG 3.37Å; I495-L499 PolarHBondContact O-N 3.41Å; L496-L499 PolarHBondContact O-N 3.25Å; L499-L501 VanDerWaalsContact C-N 3.32Å; L499-L501 PolarHBondContact O-N 2.9Å; L499-F502 HydrophobicContact CD2-CD2 4.45Å; L499-F502 PolarHBondContact O-N 3.46Å; L499-K503 PolarHBondContact O-N 2.94Å
500	L	95.1	Very high	94	Very high	103 Å²	103	51.5 Å²	51.5	54%	0.539	27%	0.271	S	S	.	.	H	α-helix	trans	-61.8	-40.9	174.5	-178.5	65.4	0	0	0	111.6	L496 L497 G498 K503	L496-L500 PolarHBondContact O-N 2.88Å; L497-L500 WeakPolarHBondContact O-CB 3.41Å; L497-L500 PolarHBondContact O-N 2.73Å; G498-L500 VanDerWaalsContact C-N 3.33Å; G498-L500 PolarHBondContact O-N 3.12Å; L500-K503 WeakPolarHBondContact O-CB 3.24Å; L500-K503 PolarHBondContact O-N 3.23Å; L500-K503 VanDerWaalsContact O-N 3.15Å
501	L	94.1	Very high	93.7	Very high	36 Å²	36	54.4 Å²	54.4	19%	0.188	27%	0.274	C	S	.	.	H	α-helix	trans	-68	-36.7	177.8	-68.1	170.7	0	0	0	112.4	T312 F316 L497 G498 L499 K503 L504 Y505	T312-L501 HydrophobicContact CG2-CD1 3.72Å; F316-L501 HydrophobicContact CD2-CD1 3.51Å; F316-L501 HydrophobicContact CE2-CD1 3.76Å; L497-L501 WeakPolarHBondContact O-CG 3.28Å; L497-L501 PolarHBondContact O-N 3.46Å; L497-L501 VanDerWaalsContact O-N 3.16Å; G498-L501 WeakPolarHBondContact O-CB 3.34Å; G498-L501 PolarHBondContact O-N 2.99Å; G498-L501 VanDerWaalsContact O-N 3.16Å; L499-L501 VanDerWaalsContact C-N 3.32Å; L499-L501 PolarHBondContact O-N 2.9Å; L501-K503 PolarHBondContact O-N 3Å; L501-K503 VanDerWaalsContact O-N 3.13Å; L501-L504 HydrophobicContact CD2-CD1 4.26Å; L501-L504 WeakPolarHBondContact O-CB 3.43Å; L501-L504 PolarHBondContact O-N 3.36Å; L501-Y505 PolarHBondContact O-N 2.94Å
502	F	93.5	Very high	93.4	Very high	3 Å²	3	54.6 Å²	54.6	1%	0.013	28%	0.275	C	S	.	.	H	α-helix	trans	-63.1	-16.6	172.7	-68	-52.2	0	0	0	113.3	L310 G313 F314 T317 K370 V373 Y374 I377 G498 L499 Y505	L310-F502 HydrophobicContact CD1-CD1 4.43Å; L310-F502 HydrophobicContact CD1-CE1 4.08Å; G313-F502 VanDerWaalsContact C-CZ 3.5Å; F314-F502 HydrophobicContact CD1-CE1 4.18Å; F314-F502 HydrophobicContact CD1-CE2 4.43Å; F314-F502 AromaticContact CD1-CZ 3.48Å; F314-F502 HydrophobicContact CD1-CZ 3.48Å; F314-F502 VanDerWaalsContact CD1-CZ 3.48Å; F314-F502 HydrophobicContact CD2-CE1 4.1Å; F314-F502 HydrophobicContact CD2-CZ 4.18Å; F314-F502 HydrophobicContact CE1-CE1 4.04Å; F314-F502 HydrophobicContact CE1-CE2 4.39Å; F314-F502 AromaticContact CE1-CZ 3.51Å; F314-F502 HydrophobicContact CE1-CZ 3.51Å; F314-F502 AromaticContact CE2-CE1 3.97Å; F314-F502 HydrophobicContact CE2-CE1 3.97Å; F314-F502 HydrophobicContact CE2-CZ 4.23Å; F314-F502 HydrophobicContact CG-CE1 4.18Å; F314-F502 AromaticContact CG-CZ 3.81Å; F314-F502 HydrophobicContact CG-CZ 3.81Å; F314-F502 AromaticContact CZ-CE1 3.92Å; F314-F502 HydrophobicContact CZ-CE1 3.92Å; F314-F502 AromaticContact CZ-CZ 3.89Å; F314-F502 HydrophobicContact CZ-CZ 3.89Å; T317-F502 HydrophobicContact CG2-CE2 4.07Å; K370-F502 WeakPolarHBondContact CE-O 3.37Å; V373-F502 HydrophobicContact CG1-CB 4.32Å; V373-F502 HydrophobicContact CG1-CD1 4.3Å; V373-F502 HydrophobicContact CG1-CD2 3.4Å; V373-F502 VanDerWaalsContact CG1-CD2 3.4Å; V373-F502 HydrophobicContact CG1-CE2 3.69Å; V373-F502 HydrophobicContact CG1-CG 3.76Å; V373-F502 HydrophobicContact CG1-CZ 4.26Å; Y374-F502 VanDerWaalsContact OH-C 3.26Å; I377-F502 HydrophobicContact CD1-CE2 3.88Å; G498-F502 WeakPolarHBondContact O-CD2 3.39Å; G498-F502 PolarHBondContact O-N 3.23Å; L499-F502 HydrophobicContact CD2-CD2 4.45Å; L499-F502 PolarHBondContact O-N 3.46Å; F502-Y505 WeakPolarHBondContact O-CB 3.43Å
503	K	90.9	Very high	93.1	Very high	152 Å²	152	59.8 Å²	59.8	66%	0.661	29%	0.293	S	S	*	.	H	α-helix	trans	-71.8	-35.3	171.6	-161.5	178	176.6	179.6	0	112	Y374 L499 L500 L501 Y505	Y374-K503 WeakPolarHBondContact OH-CA 3.23Å; Y374-K503 WeakPolarHBondContact OH-CB 3.35Å; Y374-K503 PolarHBondContact OH-N 3.27Å; L499-K503 PolarHBondContact O-N 2.94Å; L500-K503 WeakPolarHBondContact O-CB 3.24Å; L500-K503 PolarHBondContact O-N 3.23Å; L500-K503 VanDerWaalsContact O-N 3.15Å; L501-K503 PolarHBondContact O-N 3Å; L501-K503 VanDerWaalsContact O-N 3.13Å; K503-Y505 VanDerWaalsContact C-N 3.26Å; K503-Y505 PolarHBondContact O-N 3.34Å
504	L	91.5	Very high	92.9	Very high	102 Å²	102	59.3 Å²	59.3	53%	0.534	29%	0.285	S	S	.	.	H	α-helix	trans	-78.4	-12.7	179.1	-57.6	173.7	0	0	0	112.6	K309 L501	K309-L504 HydrophobicContact CD-CB 4.36Å; K309-L504 VanDerWaalsContact CD-O 3.3Å; K309-L504 WeakPolarHBondContact CD-O 3.47Å; K309-L504 PolarHBondContact NZ-O 3.45Å; L501-L504 HydrophobicContact CD2-CD1 4.26Å; L501-L504 WeakPolarHBondContact O-CB 3.43Å; L501-L504 PolarHBondContact O-N 3.36Å
505	Y	93.3	Very high	92.7	Very high	3 Å²	3	58.3 Å²	58.3	1%	0.012	28%	0.279	C	S	.	.			trans	-67.5	121.6	177	-178.6	-112	0	0	0	110.9	P306 L310 K370 M418 V422 L501 F502 K503 I507	P306-Y505 HydrophobicContact CB-CE2 4.33Å; P306-Y505 WeakPolarHBondContact O-CE2 3.17Å; L310-Y505 HydrophobicContact CB-CD2 4Å; L310-Y505 HydrophobicContact CB-CE2 3.8Å; L310-Y505 HydrophobicContact CD1-CD2 4.09Å; L310-Y505 HydrophobicContact CD1-CE1 4.28Å; L310-Y505 HydrophobicContact CD1-CE2 3.84Å; L310-Y505 HydrophobicContact CD1-CG 4.42Å; L310-Y505 HydrophobicContact CD2-CE2 4.42Å; L310-Y505 HydrophobicContact CG-CE2 4.23Å; K370-Y505 PolarHBondContact NZ-O 3.24Å; M418-Y505 HydrophobicContact CE-CD1 3.87Å; M418-Y505 HydrophobicContact CE-CE1 3.39Å; V422-Y505 HydrophobicContact CG2-CE2 3.92Å; V422-Y505 WeakPolarHBondContact CG2-OH 3.27Å; L501-Y505 PolarHBondContact O-N 2.94Å; F502-Y505 WeakPolarHBondContact O-CB 3.43Å; K503-Y505 VanDerWaalsContact C-N 3.26Å; K503-Y505 PolarHBondContact O-N 3.34Å; Y505-I507 HydrophobicContact CE1-CB 3.68Å; Y505-I507 VanDerWaalsContact CE1-O 3.23Å; Y505-I507 WeakPolarHBondContact CE1-O 3.29Å; Y505-I507 HydrophobicContact CE2-CB 4.36Å; Y505-I507 HydrophobicContact CE2-CD1 4.2Å; Y505-I507 HydrophobicContact CE2-CG1 4.44Å; Y505-I507 WeakPolarHBondContact OH-CD1 3.29Å
506	P	90.4	Very high	92.4	Very high	63 Å²	63	61 Å²	61	41%	0.409	29%	0.291	S	S	.	.			trans	-88.9	-11.3	-167.3	33.5	-35.7	0	0	0	115.2	P306 D508	P306-P506 HydrophobicContact CB-CG 3.98Å; P306-P506 HydrophobicContact CG-CG 3.85Å; P506-D508 PolarHBondContact O-N 2.9Å
507	I	91.8	Very high	92.2	Very high	2 Å²	2	62.4 Å²	62.4	1%	0.01	29%	0.293	C	S	.	.			trans	-90.6	95.8	-175	-58.6	166.2	0	0	0	109.4	P306 V422 D425 Y505 R511 R512	P306-I507 HydrophobicContact CB-CD1 3.84Å; P306-I507 HydrophobicContact CB-CG1 4.38Å; V422-I507 HydrophobicContact CG2-CD1 4.08Å; D425-I507 HydrophobicContact CB-CD1 3.75Å; Y505-I507 HydrophobicContact CE1-CB 3.68Å; Y505-I507 VanDerWaalsContact CE1-O 3.23Å; Y505-I507 WeakPolarHBondContact CE1-O 3.29Å; Y505-I507 HydrophobicContact CE2-CB 4.36Å; Y505-I507 HydrophobicContact CE2-CD1 4.2Å; Y505-I507 HydrophobicContact CE2-CG1 4.44Å; Y505-I507 WeakPolarHBondContact OH-CD1 3.29Å; I507-R511 HydrophobicContact CG2-CB 4.45Å; I507-R511 HydrophobicContact CG2-CG 4.39Å; I507-R512 HydrophobicContact CG2-CG 3.83Å
508	D	90.6	Very high	91.9	Very high	66 Å²	66	61 Å²	61	35%	0.353	29%	0.291	S	S	.	.			trans	-92.7	174.7	173.1	-65	-29	0	0	0	111.8	K370 P506 E510 R511 R512	K370-D508 WeakPolarHBondContact CD-OD1 3.49Å; K370-D508 VanDerWaalsContact CE-OD1 3.32Å; K370-D508 WeakPolarHBondContact CE-OD1 3.43Å; K370-D508 IonicContact NZ-OD1 2.77Å; K370-D508 PolarHBondContact NZ-OD1 3.29Å; K370-D508 IonicContact NZ-OD2 3.25Å; P506-D508 PolarHBondContact O-N 2.9Å; D508-E510 PolarHBondContact O-N 3.43Å; D508-R511 PolarHBondContact O-N 3.18Å; D508-R512 PolarHBondContact O-N 3.42Å
509	E	89.4	Confident	91.5	Very high	96 Å²	96	61.2 Å²	61.2	45%	0.449	29%	0.293	S	S	.	.	H	α-helix	trans	-56.7	-37.7	179.9	-164.9	63.3	-108.6	0	0	112.7	G368 R512 R513	G368-E509 WeakPolarHBondContact CA-OE2 3.44Å; E509-R512 WeakPolarHBondContact O-CB 3.17Å; E509-R512 PolarHBondContact O-N 3.28Å; E509-R512 IonicContact OE1-CZ 3.27Å; E509-R512 IonicContact OE1-NE 3.17Å; E509-R512 PolarHBondContact OE1-NE 3.44Å; E509-R512 VanDerWaalsContact OE1-NE 3.08Å; E509-R512 IonicContact OE1-NH2 3.69Å; E509-R512 IonicContact OE2-CZ 2.7Å; E509-R512 IonicContact OE2-NE 2.7Å; E509-R512 IonicContact OE2-NH2 3.64Å; E509-R512 PolarHBondContact OE2-NH2 3.48Å; E509-R513 WeakPolarHBondContact O-CB 3.42Å; E509-R513 PolarHBondContact O-N 3.49Å
510	E	90.7	Very high	91.2	Very high	87 Å²	87	64.9 Å²	64.9	41%	0.407	31%	0.309	S	S	.	.	H	α-helix	trans	-66.2	-42.5	177.2	-176.9	53.7	-148.7	0	0	111.5	D508 R512 R513 Q514	D508-E510 PolarHBondContact O-N 3.43Å; E510-R512 VanDerWaalsContact C-N 3.33Å; E510-R512 PolarHBondContact O-N 3.36Å; E510-R513 VanDerWaalsContact CD-NH2 3.26Å; E510-R513 PolarHBondContact O-N 3.12Å; E510-R513 IonicContact OE1-CZ 3.93Å; E510-R513 IonicContact OE1-NE 3.6Å; E510-R513 IonicContact OE1-NH2 3.08Å; E510-R513 PolarHBondContact OE1-NH2 2.93Å; E510-R513 IonicContact OE2-CZ 3.57Å; E510-R513 VanDerWaalsContact OE2-CZ 3.25Å; E510-R513 IonicContact OE2-NE 3.52Å; E510-R513 PolarHBondContact OE2-NE 3.17Å; E510-R513 VanDerWaalsContact OE2-NE 3.12Å; E510-R513 IonicContact OE2-NH2 2.95Å; E510-R513 PolarHBondContact OE2-NH2 2.93Å; E510-Q514 WeakPolarHBondContact O-CG 3.19Å; E510-Q514 PolarHBondContact O-N 3.3Å; E510-Q514 PolarHBondContact OE1-NE2 3Å
511	R	90.8	Very high	90.8	Very high	99 Å²	99	62.1 Å²	62.1	37%	0.374	30%	0.301	S	S	.	.	H	α-helix	trans	-64.2	-39.9	176.7	-173.9	62.9	177.1	-169.7	2.9	111.1	D425 I507 D508 Q514 N515	D425-R511 IonicContact OD1-NE 2.66Å; D425-R511 IonicContact OD1-NH2 3.12Å; I507-R511 HydrophobicContact CG2-CB 4.45Å; I507-R511 HydrophobicContact CG2-CG 4.39Å; D508-R511 PolarHBondContact O-N 3.18Å; R511-Q514 WeakPolarHBondContact O-CB 3.33Å; R511-Q514 PolarHBondContact O-N 2.93Å; R511-N515 VanDerWaalsContact O-CG 3.31Å; R511-N515 PolarHBondContact O-N 2.77Å; R511-N515 PolarHBondContact O-OD1 3.27Å
512	R	90.1	Very high	90.4	Very high	5 Å²	5	64 Å²	64	2%	0.019	31%	0.311	C	S	.	.	H	α-helix	trans	-59.3	-46.6	172.8	-77.3	-160.1	-78.3	-103.8	-7.2	112.6	K369 D421 I507 D508 E509 E510 Q514 N515 K516	K369-R512 VanDerWaalsContact CB-NH1 3.31Å; K369-R512 VanDerWaalsContact CD-NH1 3.25Å; D421-R512 HydrophobicContact CB-CG 4.46Å; D421-R512 VanDerWaalsContact OD2-CD 3.32Å; D421-R512 WeakPolarHBondContact OD2-CD 3.44Å; D421-R512 IonicContact OD2-CZ 3.47Å; D421-R512 IonicContact OD2-NE 3.82Å; D421-R512 IonicContact OD2-NH1 3.53Å; D421-R512 PolarHBondContact OD2-NH1 3.07Å; I507-R512 HydrophobicContact CG2-CG 3.83Å; D508-R512 PolarHBondContact O-N 3.42Å; E509-R512 WeakPolarHBondContact O-CB 3.17Å; E509-R512 PolarHBondContact O-N 3.28Å; E509-R512 IonicContact OE1-CZ 3.27Å; E509-R512 IonicContact OE1-NE 3.17Å; E509-R512 PolarHBondContact OE1-NE 3.44Å; E509-R512 VanDerWaalsContact OE1-NE 3.08Å; E509-R512 IonicContact OE1-NH2 3.69Å; E509-R512 IonicContact OE2-CZ 2.7Å; E509-R512 IonicContact OE2-NE 2.7Å; E509-R512 IonicContact OE2-NH2 3.64Å; E509-R512 PolarHBondContact OE2-NH2 3.48Å; E510-R512 VanDerWaalsContact C-N 3.33Å; E510-R512 PolarHBondContact O-N 3.36Å; R512-Q514 VanDerWaalsContact C-N 3.25Å; R512-Q514 PolarHBondContact O-N 3.3Å; R512-N515 PolarHBondContact O-N 2.9Å; R512-K516 WeakPolarHBondContact O-CB 3.4Å; R512-K516 PolarHBondContact O-N 2.92Å
513	R	90.1	Very high	89.9	Confident	127 Å²	127	66.2 Å²	66.2	48%	0.479	32%	0.319	S	S	.	.	H	α-helix	trans	-60.6	-38.6	178.5	-168.6	-179.2	69.5	145.2	2.7	111.4	E509 E510 K517	E509-R513 WeakPolarHBondContact O-CB 3.42Å; E509-R513 PolarHBondContact O-N 3.49Å; E510-R513 VanDerWaalsContact CD-NH2 3.26Å; E510-R513 PolarHBondContact O-N 3.12Å; E510-R513 IonicContact OE1-CZ 3.93Å; E510-R513 IonicContact OE1-NE 3.6Å; E510-R513 IonicContact OE1-NH2 3.08Å; E510-R513 PolarHBondContact OE1-NH2 2.93Å; E510-R513 IonicContact OE2-CZ 3.57Å; E510-R513 VanDerWaalsContact OE2-CZ 3.25Å; E510-R513 IonicContact OE2-NE 3.52Å; E510-R513 PolarHBondContact OE2-NE 3.17Å; E510-R513 VanDerWaalsContact OE2-NE 3.12Å; E510-R513 IonicContact OE2-NH2 2.95Å; E510-R513 PolarHBondContact OE2-NH2 2.93Å; R513-K517 WeakPolarHBondContact O-CG 3.25Å; R513-K517 PolarHBondContact O-N 2.99Å
514	Q	92.6	Very high	89.6	Confident	88 Å²	88	62.7 Å²	62.7	41%	0.411	31%	0.308	S	S	.	.	H	α-helix	trans	-64.7	-50.3	173.5	-69.4	170.5	5	0	0	111.6	E510 R511 R512 K516 K517 A518	E510-Q514 WeakPolarHBondContact O-CG 3.19Å; E510-Q514 PolarHBondContact O-N 3.3Å; E510-Q514 PolarHBondContact OE1-NE2 3Å; R511-Q514 WeakPolarHBondContact O-CB 3.33Å; R511-Q514 PolarHBondContact O-N 2.93Å; R512-Q514 VanDerWaalsContact C-N 3.25Å; R512-Q514 PolarHBondContact O-N 3.3Å; Q514-K516 VanDerWaalsContact C-N 3.31Å; Q514-K516 PolarHBondContact O-N 2.98Å; Q514-K517 PolarHBondContact O-N 3.25Å; Q514-K517 VanDerWaalsContact O-N 3.14Å; Q514-A518 PolarHBondContact O-N 3.47Å
515	N	92.6	Very high	89.2	Confident	8 Å²	8	63.6 Å²	63.6	4%	0.043	31%	0.309	C	S	.	.	H	α-helix	trans	-60	-42.2	179.7	-71.2	4.3	0	0	0	111.5	D425 L428 R511 R512 K517 A518 L519	D425-N515 WeakPolarHBondContact CA-ND2 3.26Å; D425-N515 VanDerWaalsContact CB-ND2 3.31Å; D425-N515 WeakPolarHBondContact CB-ND2 3.29Å; D425-N515 PolarHBondContact OD1-ND2 3.01Å; L428-N515 HydrophobicContact CD1-CB 3.55Å; R511-N515 VanDerWaalsContact O-CG 3.31Å; R511-N515 PolarHBondContact O-N 2.77Å; R511-N515 PolarHBondContact O-OD1 3.27Å; R512-N515 PolarHBondContact O-N 2.9Å; N515-K517 PolarHBondContact O-N 2.89Å; N515-A518 PolarHBondContact O-N 2.82Å; N515-L519 WeakPolarHBondContact O-CG 3.39Å; N515-L519 PolarHBondContact O-N 3.36Å
516	K	89.8	Confident	88.4	Confident	59 Å²	59	64.5 Å²	64.5	26%	0.257	32%	0.317	S	S	.	.	H	α-helix	trans	-58.7	-45	175.1	-178.5	174.5	-177.8	167.5	0	112.3	E188 R512 Q514 Q520	E188-K516 VanDerWaalsContact OE2-CE 3.23Å; E188-K516 WeakPolarHBondContact OE2-CE 3.19Å; E188-K516 IonicContact OE2-NZ 3.56Å; E188-K516 PolarHBondContact OE2-NZ 3.43Å; R512-K516 WeakPolarHBondContact O-CB 3.4Å; R512-K516 PolarHBondContact O-N 2.92Å; Q514-K516 VanDerWaalsContact C-N 3.31Å; Q514-K516 PolarHBondContact O-N 2.98Å; K516-Q520 WeakPolarHBondContact O-CB 3.44Å; K516-Q520 PolarHBondContact O-N 2.91Å
517	K	91.7	Very high	87.7	Confident	124 Å²	124	64.1 Å²	64.1	54%	0.539	32%	0.316	S	S	.	.	H	α-helix	trans	-64.8	-41.6	177.2	-74.5	176.9	179.1	-177	0	111.9	R513 Q514 N515 Q520 A521	R513-K517 WeakPolarHBondContact O-CG 3.25Å; R513-K517 PolarHBondContact O-N 2.99Å; Q514-K517 PolarHBondContact O-N 3.25Å; Q514-K517 VanDerWaalsContact O-N 3.14Å; N515-K517 PolarHBondContact O-N 2.89Å; K517-Q520 PolarHBondContact O-N 2.87Å; K517-A521 PolarHBondContact O-N 3.29Å
518	A	90.4	Very high	86.7	Confident	39 Å²	39	67.6 Å²	67.6	32%	0.322	34%	0.34	S	S	.	.	H	α-helix	trans	-64.5	-45.3	178.5	0	0	0	0	0	111.9	L428 Q514 N515 Q520 A521 L522	L428-A518 HydrophobicContact CD1-CB 4.01Å; L428-A518 HydrophobicContact CD2-CB 3.75Å; Q514-A518 PolarHBondContact O-N 3.47Å; N515-A518 PolarHBondContact O-N 2.82Å; A518-Q520 VanDerWaalsContact C-N 3.31Å; A518-Q520 PolarHBondContact O-N 3.28Å; A518-A521 WeakPolarHBondContact O-CB 3.39Å; A518-A521 PolarHBondContact O-N 3.49Å; A518-L522 WeakPolarHBondContact O-CG 3.3Å; A518-L522 PolarHBondContact O-N 3.41Å
519	L	87.5	Confident	85.4	Confident	6 Å²	6	66.7 Å²	66.7	3%	0.031	34%	0.339	C	S	.	.	H	α-helix	trans	-63.4	-37.7	175.1	-73.1	171.2	0	0	0	112.1	D424 L428 N515 L522 R523	D424-L519 HydrophobicContact CB-CD1 3.73Å; L428-L519 HydrophobicContact CD1-CG 4.28Å; L428-L519 HydrophobicContact CD2-CD2 3.77Å; L428-L519 HydrophobicContact CD2-CG 3.93Å; L428-L519 HydrophobicContact CG-CD2 4.05Å; L428-L519 HydrophobicContact CG-CG 4.11Å; N515-L519 WeakPolarHBondContact O-CG 3.39Å; N515-L519 PolarHBondContact O-N 3.36Å; L519-L522 PolarHBondContact O-N 3.41Å; L519-R523 VanDerWaalsContact O-CG 3.28Å; L519-R523 WeakPolarHBondContact O-CG 3.37Å; L519-R523 PolarHBondContact O-N 3.09Å; L519-R523 VanDerWaalsContact O-N 3.1Å
520	Q	88	Confident	83.7	Confident	94 Å²	94	63.5 Å²	63.5	44%	0.439	33%	0.332	S	S	.	.	H	α-helix	trans	-64.8	-41.2	175	-171.2	174.1	-5.7	0	0	111.9	K516 K517 A518 L522 R523 D524	K516-Q520 WeakPolarHBondContact O-CB 3.44Å; K516-Q520 PolarHBondContact O-N 2.91Å; K517-Q520 PolarHBondContact O-N 2.87Å; A518-Q520 VanDerWaalsContact C-N 3.31Å; A518-Q520 PolarHBondContact O-N 3.28Å; Q520-L522 PolarHBondContact O-N 3.25Å; Q520-R523 WeakPolarHBondContact O-CB 3.24Å; Q520-R523 PolarHBondContact O-N 2.99Å; Q520-D524 PolarHBondContact O-N 3.17Å
521	A	88.1	Confident	81.7	Confident	45 Å²	45	63.2 Å²	63.2	37%	0.372	34%	0.339	S	S	.	.	H	α-helix	trans	-60.4	-45	175.5	0	0	0	0	0	112	K517 A518 R523 D524 E525	K517-A521 PolarHBondContact O-N 3.29Å; A518-A521 WeakPolarHBondContact O-CB 3.39Å; A518-A521 PolarHBondContact O-N 3.49Å; A521-R523 VanDerWaalsContact C-N 3.28Å; A521-R523 PolarHBondContact O-N 2.96Å; A521-D524 PolarHBondContact O-N 3.08Å; A521-E525 WeakPolarHBondContact O-CG 3.08Å; A521-E525 PolarHBondContact O-N 2.76Å
522	L	84.9	Confident	79.6	Confident	75 Å²	75	61.9 Å²	61.9	39%	0.393	35%	0.345	S	S	.	.	H	α-helix	trans	-60.3	-37.2	175.6	-68.9	173.7	0	0	0	112.6	L428 A518 L519 Q520 A526	L428-L522 HydrophobicContact CD2-CD1 3.92Å; A518-L522 WeakPolarHBondContact O-CG 3.3Å; A518-L522 PolarHBondContact O-N 3.41Å; L519-L522 PolarHBondContact O-N 3.41Å; Q520-L522 PolarHBondContact O-N 3.25Å; L522-A526 WeakPolarHBondContact O-CB 3.22Å; L522-A526 PolarHBondContact O-N 3.45Å
523	R	82.6	Confident	77.6	Confident	50 Å²	50	67.5 Å²	67.5	19%	0.189	37%	0.371	C	S	.	.	H	α-helix	trans	-67.8	-41.5	175.8	-70.3	166.8	-179.5	156.8	4.3	111.9	T187 E282 L519 Q520 A521 S527	T187-R523 PolarHBondContact O-NH1 2.71Å; T187-R523 PolarHBondContact O-NH2 2.7Å; E282-R523 IonicContact OE1-CZ 2.68Å; E282-R523 IonicContact OE1-NE 3.99Å; E282-R523 PolarHBondContact OE1-NE 3.02Å; E282-R523 IonicContact OE1-NH2 3.43Å; E282-R523 PolarHBondContact OE1-NH2 2.9Å; L519-R523 VanDerWaalsContact O-CG 3.28Å; L519-R523 WeakPolarHBondContact O-CG 3.37Å; L519-R523 PolarHBondContact O-N 3.09Å; L519-R523 VanDerWaalsContact O-N 3.1Å; Q520-R523 WeakPolarHBondContact O-CB 3.24Å; Q520-R523 PolarHBondContact O-N 2.99Å; A521-R523 VanDerWaalsContact C-N 3.28Å; A521-R523 PolarHBondContact O-N 2.96Å; R523-S527 WeakPolarHBondContact O-CB 3.3Å; R523-S527 PolarHBondContact O-N 3.13Å; R523-S527 PolarHBondContact O-OG 3.07Å
524	D	85.1	Confident	75.6	Confident	78 Å²	78	65.1 Å²	65.1	42%	0.417	37%	0.371	S	S	.	.	H	α-helix	trans	-66.5	-43	178.8	-69.3	-27.4	0	0	0	110.3	Q520 A521 S527 S528	Q520-D524 PolarHBondContact O-N 3.17Å; A521-D524 PolarHBondContact O-N 3.08Å; D524-S527 PolarHBondContact O-N 3.46Å; D524-S527 PolarHBondContact O-OG 3.01Å; D524-S528 PolarHBondContact O-N 3.37Å
525	E	82.9	Confident	73.3	Confident	122 Å²	122	65.9 Å²	65.9	57%	0.57	38%	0.378	S	S	*	.	H	α-helix	trans	-57.8	-51.8	172.8	-74.1	174	-169.5	0	0	111.9	A521 S527 S528 S529	A521-E525 WeakPolarHBondContact O-CG 3.08Å; A521-E525 PolarHBondContact O-N 2.76Å; E525-S527 VanDerWaalsContact C-N 3.28Å; E525-S527 PolarHBondContact O-N 3.36Å; E525-S528 PolarHBondContact O-N 3.28Å; E525-S528 VanDerWaalsContact O-N 3.08Å; E525-S528 PolarHBondContact O-OG 2.72Å; E525-S529 PolarHBondContact O-N 3.25Å; E525-S529 PolarHBondContact O-OG 3.49Å
526	A	76.1	Confident	71.1	Confident	21 Å²	21	68.8 Å²	68.8	17%	0.174	40%	0.399	C	S	.	.	H	α-helix	trans	-61.7	-34.3	178.5	0	0	0	0	0	113.1	L522 S529 G530	L522-A526 WeakPolarHBondContact O-CB 3.22Å; L522-A526 PolarHBondContact O-N 3.45Å; A526-S529 WeakPolarHBondContact CA-OG 3.43Å; A526-S529 PolarHBondContact O-OG 3.07Å; A526-G530 PolarHBondContact O-N 3.1Å; A526-G530 VanDerWaalsContact O-N 3.13Å
527	S	75.1	Confident	69.2	Low	55 Å²	55	70.3 Å²	70.3	39%	0.385	41%	0.413	S	S	.	.	H	α-helix	trans	-70.7	-33.6	175.5	74.6	0	0	0	0	112.5	R523 D524 E525 C531	R523-S527 WeakPolarHBondContact O-CB 3.3Å; R523-S527 PolarHBondContact O-N 3.13Å; R523-S527 PolarHBondContact O-OG 3.07Å; D524-S527 PolarHBondContact O-N 3.46Å; D524-S527 PolarHBondContact O-OG 3.01Å; E525-S527 VanDerWaalsContact C-N 3.28Å; E525-S527 PolarHBondContact O-N 3.36Å; S527-C531 PolarHBondContact O-N 2.88Å
528	S	71.9	Confident	67.2	Low	75 Å²	75	70.5 Å²	70.5	52%	0.524	42%	0.416	S	S	.	.	H	α-helix	trans	-73.3	-38.5	177.3	72.3	0	0	0	0	112.6	D524 E525 C531 S532	D524-S528 PolarHBondContact O-N 3.37Å; E525-S528 PolarHBondContact O-N 3.28Å; E525-S528 VanDerWaalsContact O-N 3.08Å; E525-S528 PolarHBondContact O-OG 2.72Å; S528-C531 PolarHBondContact O-N 3.44Å; S528-S532 PolarHBondContact O-N 2.81Å
529	S	62.1	Low	65.2	Low	48 Å²	48	74.4 Å²	74.4	34%	0.336	43%	0.431	S	S	.	.	H	α-helix	trans	-68.1	-40.6	175.6	59.4	0	0	0	0	111.7	E525 A526 C531 S532 E533	E525-S529 PolarHBondContact O-N 3.25Å; E525-S529 PolarHBondContact O-OG 3.49Å; A526-S529 WeakPolarHBondContact CA-OG 3.43Å; A526-S529 PolarHBondContact O-OG 3.07Å; S529-C531 PolarHBondContact O-N 2.8Å; S529-S532 PolarHBondContact O-N 3.03Å; S529-S532 PolarHBondContact O-OG 3.16Å; S529-E533 PolarHBondContact O-N 2.97Å
530	G	55.6	Low	63.4	Low	29 Å²	29	77.4 Å²	77.4	30%	0.299	46%	0.456	S	S	.	.	H	α-helix	trans	-62	-38.1	175.8	0	0	0	0	0	113.7	A526 T534	A526-G530 PolarHBondContact O-N 3.1Å; A526-G530 VanDerWaalsContact O-N 3.13Å; G530-T534 PolarHBondContact O-N 2.92Å; G530-T534 PolarHBondContact O-OG1 3.2Å
531	C	47.1	Very low	61.5	Low	80 Å²	80	77.2 Å²	77.2	54%	0.541	47%	0.466	S	S	.	.	H	α-helix	trans	-65.8	-36.8	173.9	-93.9	0	0	0	0	112.7	S527 S528 S529 T534 D535	S527-C531 PolarHBondContact O-N 2.88Å; S528-C531 PolarHBondContact O-N 3.44Å; S529-C531 PolarHBondContact O-N 2.8Å; C531-T534 WeakPolarHBondContact CA-OG1 3.22Å; C531-T534 PolarHBondContact O-N 3.05Å; C531-T534 PolarHBondContact O-OG1 3Å; C531-D535 PolarHBondContact O-N 3.38Å; C531-D535 VanDerWaalsContact O-N 3.15Å
532	S	48.4	Very low	59.7	Low	71 Å²	71	81.9 Å²	81.9	50%	0.497	48%	0.483	S	S	.	.	H	α-helix	trans	-66.8	-36.1	179.9	71.5	0	0	0	0	113	S528 S529 S536	S528-S532 PolarHBondContact O-N 2.81Å; S529-S532 PolarHBondContact O-N 3.03Å; S529-S532 PolarHBondContact O-OG 3.16Å; S532-S536 PolarHBondContact O-N 3.15Å; S532-S536 PolarHBondContact O-OG 3.37Å
533	E	46.7	Very low	57.6	Low	123 Å²	123	87.9 Å²	87.9	58%	0.575	51%	0.514	S	S	*	.	H	α-helix	trans	-70.9	-38.7	177.2	-74.8	-175.1	151.6	0	0	112.5	S529 S536 T537	S529-E533 PolarHBondContact O-N 2.97Å; E533-S536 WeakPolarHBondContact CA-OG 3.49Å; E533-S536 PolarHBondContact O-N 3.38Å; E533-S536 PolarHBondContact O-OG 3.09Å; E533-T537 PolarHBondContact O-N 3.49Å; E533-T537 PolarHBondContact O-OG1 2.93Å
534	T	48.3	Very low	56.4	Low	78 Å²	78	89.8 Å²	89.8	48%	0.479	53%	0.53	S	S	.	.	H	α-helix	trans	-64.2	-40.4	174.3	32.7	0	0	0	0	113.1	G530 C531 S536 T537 E538	G530-T534 PolarHBondContact O-N 2.92Å; G530-T534 PolarHBondContact O-OG1 3.2Å; C531-T534 WeakPolarHBondContact CA-OG1 3.22Å; C531-T534 PolarHBondContact O-N 3.05Å; C531-T534 PolarHBondContact O-OG1 3Å; T534-S536 PolarHBondContact O-N 3.03Å; T534-T537 WeakPolarHBondContact CA-OG1 3.25Å; T534-T537 PolarHBondContact O-N 3.33Å; T534-T537 PolarHBondContact O-OG1 3.06Å; T534-T537 VanDerWaalsContact O-OG1 3.1Å; T534-E538 PolarHBondContact O-N 2.81Å
535	D	44	Very low	54.9	Low	103 Å²	103	90.4 Å²	90.4	55%	0.551	54%	0.536	S	S	*	.	H	α-helix	trans	-66.4	-38.6	176.9	-83.5	-10.6	0	0	0	111.5	C531 L539	C531-D535 PolarHBondContact O-N 3.38Å; C531-D535 VanDerWaalsContact O-N 3.15Å; D535-L539 WeakPolarHBondContact O-CB 2.89Å; D535-L539 PolarHBondContact O-N 3.19Å
536	S	47.8	Very low	53.3	Low	70 Å²	70	88.6 Å²	88.6	49%	0.49	53%	0.534	S	S	.	.	H	α-helix	trans	-71.8	-28	176.3	45.2	0	0	0	0	114.1	S532 E533 T534 A540	S532-S536 PolarHBondContact O-N 3.15Å; S532-S536 PolarHBondContact O-OG 3.37Å; E533-S536 WeakPolarHBondContact CA-OG 3.49Å; E533-S536 PolarHBondContact O-N 3.38Å; E533-S536 PolarHBondContact O-OG 3.09Å; T534-S536 PolarHBondContact O-N 3.03Å; S536-A540 WeakPolarHBondContact O-CB 3.1Å; S536-A540 PolarHBondContact O-N 2.91Å; S536-A540 VanDerWaalsContact O-N 3.12Å
537	T	49.1	Very low	52	Low	90 Å²	90	92.6 Å²	92.6	55%	0.552	56%	0.555	S	S	*	*	H	α-helix	trans	-81.6	-34.6	176.7	40.8	0	0	0	0	112.5	E533 T534 A540 S541	E533-T537 PolarHBondContact O-N 3.49Å; E533-T537 PolarHBondContact O-OG1 2.93Å; T534-T537 WeakPolarHBondContact CA-OG1 3.25Å; T534-T537 PolarHBondContact O-N 3.33Å; T534-T537 PolarHBondContact O-OG1 3.06Å; T534-T537 VanDerWaalsContact O-OG1 3.1Å; T537-A540 PolarHBondContact O-N 3.22Å; T537-S541 PolarHBondContact O-N 2.94Å; T537-S541 VanDerWaalsContact O-N 3.14Å; T537-S541 PolarHBondContact O-OG 2.78Å
538	E	50.2	Low	50.5	Low	129 Å²	129	94.9 Å²	94.9	60%	0.603	57%	0.566	S	S	*	*	H	α-helix	trans	-64.1	-44	168.2	-85.4	-164.9	150.4	0	0	111.2	T534 A540 S541 I542	T534-E538 PolarHBondContact O-N 2.81Å; E538-A540 VanDerWaalsContact C-N 3.31Å; E538-A540 PolarHBondContact O-N 2.8Å; E538-S541 PolarHBondContact O-N 3.3Å; E538-S541 VanDerWaalsContact O-N 3.12Å; E538-S541 PolarHBondContact O-OG 3.47Å; E538-I542 WeakPolarHBondContact O-CD1 3.23Å; E538-I542 WeakPolarHBondContact O-CG1 3.34Å; E538-I542 PolarHBondContact O-N 2.64Å
539	L	47.7	Very low	49.1	Very low	121 Å²	121	96.3 Å²	96.3	63%	0.634	57%	0.569	S	S	*	*	H	α-helix	trans	-62.2	-36	176	-113	101.6	0	0	0	113.2	D535 S541 I542 L543	D535-L539 WeakPolarHBondContact O-CB 2.89Å; D535-L539 PolarHBondContact O-N 3.19Å; L539-S541 VanDerWaalsContact C-N 3.3Å; L539-I542 PolarHBondContact O-N 3.04Å; L539-L543 PolarHBondContact O-N 2.91Å
540	A	49	Very low	48.2	Very low	69 Å²	69	99.7 Å²	99.7	57%	0.57	59%	0.586	S	S	*	*	H	α-helix	trans	-75.2	-16.6	177.1	0	0	0	0	0	113.7	S536 T537 E538	S536-A540 WeakPolarHBondContact O-CB 3.1Å; S536-A540 PolarHBondContact O-N 2.91Å; S536-A540 VanDerWaalsContact O-N 3.12Å; T537-A540 PolarHBondContact O-N 3.22Å; E538-A540 VanDerWaalsContact C-N 3.31Å; E538-A540 PolarHBondContact O-N 2.8Å
541	S	48.1	Very low	47.6	Very low	90 Å²	90	105.2 Å²	105.2	63%	0.629	61%	0.608	S	S	*	*	H	α-helix	trans	-90.6	-9.6	174.2	70.1	0	0	0	0	113.8	T537 E538 L539	T537-S541 PolarHBondContact O-N 2.94Å; T537-S541 VanDerWaalsContact O-N 3.14Å; T537-S541 PolarHBondContact O-OG 2.78Å; E538-S541 PolarHBondContact O-N 3.3Å; E538-S541 VanDerWaalsContact O-N 3.12Å; E538-S541 PolarHBondContact O-OG 3.47Å; L539-S541 VanDerWaalsContact C-N 3.3Å
542	I	51.6	Low	47.7	Very low	142 Å²	142	107.3 Å²	107.3	73%	0.728	61%	0.613	S	S	*	*			trans	-102.9	-7.7	-179.9	-64.5	168.8	0	0	0	111.7	E538 L539	E538-I542 WeakPolarHBondContact O-CD1 3.23Å; E538-I542 WeakPolarHBondContact O-CG1 3.34Å; E538-I542 PolarHBondContact O-N 2.64Å; L539-I542 PolarHBondContact O-N 3.04Å
543	L	41.1	Very low	47.6	Very low	201 Å²	201	110.5 Å²	110.5	100%	1.052	62%	0.624	S	S	*	*			trans	-103.8	0	169.1	-81.1	164.2	0	0	0	110.2	L539	L539-L543 PolarHBondContact O-N 2.91Å

Retrieved 543 of 543 residues in 294.5 ms (Link to these results)

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